data_9F09
# 
_entry.id   9F09 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9F09         pdb_00009f09 10.2210/pdb9f09/pdb 
WWPDB D_1292137935 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_database_PDB_caveat.id     1 
_database_PDB_caveat.text   '2DR B 201 HAS WRONG CHIRALITY AT ATOM C1' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9F09 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gideon.grogan@york.ac.uk 
_pdbx_contact_author.name_first         Gideon 
_pdbx_contact_author.name_last          Grogan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1383-7056 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ascham, A.'    1 ?                   
'Salihovic, A.' 2 ?                   
'Burley, G.'    3 0000-0002-4896-113X 
'Grogan, G.'    4 0000-0003-1383-7056 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Chem Sci' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-6520 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                15399 
_citation.page_last                 15407 
_citation.title                     
;Gram-scale enzymatic synthesis of 2'-deoxyribonucleoside analogues using nucleoside transglycosylase-2.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1039/d4sc04938a 
_citation.pdbx_database_id_PubMed   39234214 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Salihovic, A.'       1 0009-0004-4710-0145 
primary 'Ascham, A.'          2 0000-0002-1930-4667 
primary 'Taladriz-Sender, A.' 3 0000-0002-8274-4761 
primary 'Bryson, S.'          4 ?                   
primary 'Withers, J.M.'       5 ?                   
primary 'McKean, I.J.W.'      6 ?                   
primary 'Hoskisson, P.A.'     7 0000-0003-4332-1640 
primary 'Grogan, G.'          8 0000-0003-1383-7056 
primary 'Burley, G.A.'        9 0000-0002-4896-113X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Nucleoside deoxyribosyltransferase'      18098.354 2  ? ? ? ? 
2 non-polymer syn "2'-DEOXYCYTIDINE"                        227.217   1  ? ? ? ? 
3 non-polymer syn '7-bromanyl-3~{H}-imidazo[4,5-b]pyridine' 198.020   2  ? ? ? ? 
4 non-polymer syn 2-deoxy-beta-D-erythro-pentofuranose      134.130   1  ? ? ? ? 
5 water       nat water                                     18.015    56 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTND
IMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTND
IMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 "2'-DEOXYCYTIDINE"                        DCZ   
3 '7-bromanyl-3~{H}-imidazo[4,5-b]pyridine' A1H8P 
4 2-deoxy-beta-D-erythro-pentofuranose      2DR   
5 water                                     HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   LYS n 
1 4   LYS n 
1 5   THR n 
1 6   ILE n 
1 7   TYR n 
1 8   PHE n 
1 9   GLY n 
1 10  ALA n 
1 11  GLY n 
1 12  TRP n 
1 13  PHE n 
1 14  THR n 
1 15  ASP n 
1 16  ARG n 
1 17  GLN n 
1 18  ASN n 
1 19  LYS n 
1 20  ALA n 
1 21  TYR n 
1 22  LYS n 
1 23  GLU n 
1 24  ALA n 
1 25  MET n 
1 26  GLU n 
1 27  ALA n 
1 28  LEU n 
1 29  LYS n 
1 30  GLU n 
1 31  ASN n 
1 32  PRO n 
1 33  THR n 
1 34  ILE n 
1 35  ASP n 
1 36  LEU n 
1 37  GLU n 
1 38  ASN n 
1 39  SER n 
1 40  TYR n 
1 41  VAL n 
1 42  PRO n 
1 43  LEU n 
1 44  ASP n 
1 45  ASN n 
1 46  GLN n 
1 47  TYR n 
1 48  LYS n 
1 49  GLY n 
1 50  ILE n 
1 51  ARG n 
1 52  VAL n 
1 53  ASP n 
1 54  GLU n 
1 55  HIS n 
1 56  PRO n 
1 57  GLU n 
1 58  TYR n 
1 59  LEU n 
1 60  HIS n 
1 61  ASP n 
1 62  LYS n 
1 63  VAL n 
1 64  TRP n 
1 65  ALA n 
1 66  THR n 
1 67  ALA n 
1 68  THR n 
1 69  TYR n 
1 70  ASN n 
1 71  ASN n 
1 72  ASP n 
1 73  LEU n 
1 74  ASN n 
1 75  GLY n 
1 76  ILE n 
1 77  LYS n 
1 78  THR n 
1 79  ASN n 
1 80  ASP n 
1 81  ILE n 
1 82  MET n 
1 83  LEU n 
1 84  GLY n 
1 85  VAL n 
1 86  TYR n 
1 87  ILE n 
1 88  PRO n 
1 89  ASP n 
1 90  GLU n 
1 91  GLU n 
1 92  ASP n 
1 93  VAL n 
1 94  GLY n 
1 95  LEU n 
1 96  GLY n 
1 97  MET n 
1 98  GLU n 
1 99  LEU n 
1 100 GLY n 
1 101 TYR n 
1 102 ALA n 
1 103 LEU n 
1 104 SER n 
1 105 GLN n 
1 106 GLY n 
1 107 LYS n 
1 108 TYR n 
1 109 VAL n 
1 110 LEU n 
1 111 LEU n 
1 112 VAL n 
1 113 ILE n 
1 114 PRO n 
1 115 ASP n 
1 116 GLU n 
1 117 ASP n 
1 118 TYR n 
1 119 GLY n 
1 120 LYS n 
1 121 PRO n 
1 122 ILE n 
1 123 ASN n 
1 124 LEU n 
1 125 MET n 
1 126 SER n 
1 127 TRP n 
1 128 GLY n 
1 129 VAL n 
1 130 SER n 
1 131 ASP n 
1 132 ASN n 
1 133 VAL n 
1 134 ILE n 
1 135 LYS n 
1 136 MET n 
1 137 SER n 
1 138 GLN n 
1 139 LEU n 
1 140 LYS n 
1 141 ASP n 
1 142 PHE n 
1 143 ASN n 
1 144 PHE n 
1 145 ASN n 
1 146 LYS n 
1 147 PRO n 
1 148 ARG n 
1 149 PHE n 
1 150 ASP n 
1 151 PHE n 
1 152 TYR n 
1 153 GLU n 
1 154 GLY n 
1 155 ALA n 
1 156 VAL n 
1 157 TYR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   157 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ntd 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Lactobacillus leichmannii' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     28039 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
2DR   'D-saccharide, beta linking' . 2-deoxy-beta-D-erythro-pentofuranose      
'2-deoxy-beta-D-ribofuranose; 2-deoxy-beta-D-erythro-pentose; 2-deoxy-D-erythro-pentose; 2-deoxy-erythro-pentose' 'C5 H10 O4'      
134.130 
A1H8P non-polymer                  . '7-bromanyl-3~{H}-imidazo[4,5-b]pyridine' ? 'C6 H4 Br N3'    198.020 
ALA   'L-peptide linking'          y ALANINE                                   ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking'          y ARGININE                                  ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking'          y ASPARAGINE                                ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking'          y 'ASPARTIC ACID'                           ? 'C4 H7 N O4'     133.103 
DCZ   'DNA OH 5 prime terminus'    . "2'-DEOXYCYTIDINE"                        ? 'C9 H13 N3 O4'   227.217 
GLN   'L-peptide linking'          y GLUTAMINE                                 ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking'          y 'GLUTAMIC ACID'                           ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'            y GLYCINE                                   ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking'          y HISTIDINE                                 ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer                  . WATER                                     ? 'H2 O'           18.015  
ILE   'L-peptide linking'          y ISOLEUCINE                                ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking'          y LEUCINE                                   ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking'          y LYSINE                                    ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking'          y METHIONINE                                ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking'          y PHENYLALANINE                             ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking'          y PROLINE                                   ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking'          y SERINE                                    ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking'          y THREONINE                                 ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking'          y TRYPTOPHAN                                ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking'          y TYROSINE                                  ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking'          y VALINE                                    ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   PRO 2   2   2   PRO PRO A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   LYS 4   4   4   LYS LYS A . n 
A 1 5   THR 5   5   5   THR THR A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   TYR 7   7   7   TYR TYR A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   GLY 9   9   9   GLY GLY A . n 
A 1 10  ALA 10  10  10  ALA ALA A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  TRP 12  12  12  TRP TRP A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  THR 14  14  14  THR THR A . n 
A 1 15  ASP 15  15  15  ASP ASP A . n 
A 1 16  ARG 16  16  16  ARG ARG A . n 
A 1 17  GLN 17  17  17  GLN GLN A . n 
A 1 18  ASN 18  18  18  ASN ASN A . n 
A 1 19  LYS 19  19  19  LYS LYS A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  TYR 21  21  21  TYR TYR A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  GLU 23  23  23  GLU GLU A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  MET 25  25  25  MET MET A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  LEU 28  28  28  LEU LEU A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  ILE 34  34  34  ILE ILE A . n 
A 1 35  ASP 35  35  35  ASP ASP A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  GLU 37  37  37  GLU GLU A . n 
A 1 38  ASN 38  38  38  ASN ASN A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  TYR 40  40  40  TYR TYR A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  ASP 44  44  44  ASP ASP A . n 
A 1 45  ASN 45  45  45  ASN ASN A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  TYR 47  47  47  TYR TYR A . n 
A 1 48  LYS 48  48  48  LYS LYS A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  ILE 50  50  50  ILE ILE A . n 
A 1 51  ARG 51  51  51  ARG ARG A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  ASP 53  53  53  ASP ASP A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  HIS 55  55  55  HIS HIS A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  GLU 57  57  57  GLU GLU A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  TRP 64  64  64  TRP TRP A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  ASN 70  70  70  ASN ASN A . n 
A 1 71  ASN 71  71  71  ASN ASN A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  GLY 75  75  75  GLY GLY A . n 
A 1 76  ILE 76  76  76  ILE ILE A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  ASP 80  80  80  ASP ASP A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  MET 82  82  82  MET MET A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  TYR 86  86  86  TYR TYR A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  PRO 88  88  88  PRO PRO A . n 
A 1 89  ASP 89  89  89  ASP ASP A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  ASP 92  92  92  ASP ASP A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  MET 97  97  97  MET MET A . n 
A 1 98  GLU 98  98  98  GLU GLU A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 SER 104 104 104 SER SER A . n 
A 1 105 GLN 105 105 105 GLN GLN A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 LYS 107 107 107 LYS LYS A . n 
A 1 108 TYR 108 108 108 TYR TYR A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 VAL 112 112 112 VAL VAL A . n 
A 1 113 ILE 113 113 113 ILE ILE A . n 
A 1 114 PRO 114 114 114 PRO PRO A . n 
A 1 115 ASP 115 115 115 ASP ASP A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 LYS 120 120 120 LYS LYS A . n 
A 1 121 PRO 121 121 121 PRO PRO A . n 
A 1 122 ILE 122 122 122 ILE ILE A . n 
A 1 123 ASN 123 123 123 ASN ASN A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 MET 125 125 125 MET MET A . n 
A 1 126 SER 126 126 126 SER SER A . n 
A 1 127 TRP 127 127 127 TRP TRP A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 VAL 129 129 129 VAL VAL A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 ASP 131 131 131 ASP ASP A . n 
A 1 132 ASN 132 132 132 ASN ASN A . n 
A 1 133 VAL 133 133 133 VAL VAL A . n 
A 1 134 ILE 134 134 134 ILE ILE A . n 
A 1 135 LYS 135 135 135 LYS LYS A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 ASP 141 141 141 ASP ASP A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 PHE 144 144 144 PHE PHE A . n 
A 1 145 ASN 145 145 145 ASN ASN A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 PRO 147 147 147 PRO PRO A . n 
A 1 148 ARG 148 148 148 ARG ARG A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 PHE 151 151 151 PHE PHE A . n 
A 1 152 TYR 152 152 152 TYR TYR A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 ALA 155 155 155 ALA ALA A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 TYR 157 157 157 TYR TYR A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   PRO 2   2   2   PRO PRO B . n 
B 1 3   LYS 3   3   3   LYS LYS B . n 
B 1 4   LYS 4   4   4   LYS LYS B . n 
B 1 5   THR 5   5   5   THR THR B . n 
B 1 6   ILE 6   6   6   ILE ILE B . n 
B 1 7   TYR 7   7   7   TYR TYR B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   GLY 9   9   9   GLY GLY B . n 
B 1 10  ALA 10  10  10  ALA ALA B . n 
B 1 11  GLY 11  11  11  GLY GLY B . n 
B 1 12  TRP 12  12  12  TRP TRP B . n 
B 1 13  PHE 13  13  13  PHE PHE B . n 
B 1 14  THR 14  14  14  THR THR B . n 
B 1 15  ASP 15  15  15  ASP ASP B . n 
B 1 16  ARG 16  16  16  ARG ARG B . n 
B 1 17  GLN 17  17  17  GLN GLN B . n 
B 1 18  ASN 18  18  18  ASN ASN B . n 
B 1 19  LYS 19  19  19  LYS LYS B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  TYR 21  21  21  TYR TYR B . n 
B 1 22  LYS 22  22  22  LYS LYS B . n 
B 1 23  GLU 23  23  23  GLU GLU B . n 
B 1 24  ALA 24  24  24  ALA ALA B . n 
B 1 25  MET 25  25  25  MET MET B . n 
B 1 26  GLU 26  26  26  GLU GLU B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  LEU 28  28  28  LEU LEU B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  ASN 31  31  31  ASN ASN B . n 
B 1 32  PRO 32  32  32  PRO PRO B . n 
B 1 33  THR 33  33  33  THR THR B . n 
B 1 34  ILE 34  34  34  ILE ILE B . n 
B 1 35  ASP 35  35  35  ASP ASP B . n 
B 1 36  LEU 36  36  36  LEU LEU B . n 
B 1 37  GLU 37  37  37  GLU GLU B . n 
B 1 38  ASN 38  38  38  ASN ASN B . n 
B 1 39  SER 39  39  39  SER SER B . n 
B 1 40  TYR 40  40  40  TYR TYR B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  LEU 43  43  43  LEU LEU B . n 
B 1 44  ASP 44  44  44  ASP ASP B . n 
B 1 45  ASN 45  45  45  ASN ASN B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  TYR 47  47  47  TYR TYR B . n 
B 1 48  LYS 48  48  48  LYS LYS B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  ILE 50  50  50  ILE ILE B . n 
B 1 51  ARG 51  51  51  ARG ARG B . n 
B 1 52  VAL 52  52  52  VAL VAL B . n 
B 1 53  ASP 53  53  53  ASP ASP B . n 
B 1 54  GLU 54  54  54  GLU GLU B . n 
B 1 55  HIS 55  55  55  HIS HIS B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  GLU 57  57  57  GLU GLU B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  LEU 59  59  59  LEU LEU B . n 
B 1 60  HIS 60  60  60  HIS HIS B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  LYS 62  62  62  LYS LYS B . n 
B 1 63  VAL 63  63  63  VAL VAL B . n 
B 1 64  TRP 64  64  64  TRP TRP B . n 
B 1 65  ALA 65  65  65  ALA ALA B . n 
B 1 66  THR 66  66  66  THR THR B . n 
B 1 67  ALA 67  67  67  ALA ALA B . n 
B 1 68  THR 68  68  68  THR THR B . n 
B 1 69  TYR 69  69  69  TYR TYR B . n 
B 1 70  ASN 70  70  70  ASN ASN B . n 
B 1 71  ASN 71  71  71  ASN ASN B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  GLY 75  75  75  GLY GLY B . n 
B 1 76  ILE 76  76  76  ILE ILE B . n 
B 1 77  LYS 77  77  77  LYS LYS B . n 
B 1 78  THR 78  78  78  THR THR B . n 
B 1 79  ASN 79  79  79  ASN ASN B . n 
B 1 80  ASP 80  80  80  ASP ASP B . n 
B 1 81  ILE 81  81  81  ILE ILE B . n 
B 1 82  MET 82  82  82  MET MET B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  GLY 84  84  84  GLY GLY B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  TYR 86  86  86  TYR TYR B . n 
B 1 87  ILE 87  87  87  ILE ILE B . n 
B 1 88  PRO 88  88  88  PRO PRO B . n 
B 1 89  ASP 89  89  89  ASP ASP B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  ASP 92  92  92  ASP ASP B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  GLY 96  96  96  GLY GLY B . n 
B 1 97  MET 97  97  97  MET MET B . n 
B 1 98  GLU 98  98  98  GLU GLU B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 ALA 102 102 102 ALA ALA B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 SER 104 104 104 SER SER B . n 
B 1 105 GLN 105 105 105 GLN GLN B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 LYS 107 107 107 LYS LYS B . n 
B 1 108 TYR 108 108 108 TYR TYR B . n 
B 1 109 VAL 109 109 109 VAL VAL B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 LEU 111 111 111 LEU LEU B . n 
B 1 112 VAL 112 112 112 VAL VAL B . n 
B 1 113 ILE 113 113 113 ILE ILE B . n 
B 1 114 PRO 114 114 114 PRO PRO B . n 
B 1 115 ASP 115 115 115 ASP ASP B . n 
B 1 116 GLU 116 116 116 GLU GLU B . n 
B 1 117 ASP 117 117 117 ASP ASP B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 GLY 119 119 119 GLY GLY B . n 
B 1 120 LYS 120 120 120 LYS LYS B . n 
B 1 121 PRO 121 121 121 PRO PRO B . n 
B 1 122 ILE 122 122 122 ILE ILE B . n 
B 1 123 ASN 123 123 123 ASN ASN B . n 
B 1 124 LEU 124 124 124 LEU LEU B . n 
B 1 125 MET 125 125 125 MET MET B . n 
B 1 126 SER 126 126 126 SER SER B . n 
B 1 127 TRP 127 127 127 TRP TRP B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 VAL 129 129 129 VAL VAL B . n 
B 1 130 SER 130 130 130 SER SER B . n 
B 1 131 ASP 131 131 131 ASP ASP B . n 
B 1 132 ASN 132 132 132 ASN ASN B . n 
B 1 133 VAL 133 133 133 VAL VAL B . n 
B 1 134 ILE 134 134 134 ILE ILE B . n 
B 1 135 LYS 135 135 135 LYS LYS B . n 
B 1 136 MET 136 136 136 MET MET B . n 
B 1 137 SER 137 137 137 SER SER B . n 
B 1 138 GLN 138 138 138 GLN GLN B . n 
B 1 139 LEU 139 139 139 LEU LEU B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 ASP 141 141 141 ASP ASP B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 PHE 144 144 144 PHE PHE B . n 
B 1 145 ASN 145 145 145 ASN ASN B . n 
B 1 146 LYS 146 146 146 LYS LYS B . n 
B 1 147 PRO 147 147 147 PRO PRO B . n 
B 1 148 ARG 148 148 148 ARG ARG B . n 
B 1 149 PHE 149 149 149 PHE PHE B . n 
B 1 150 ASP 150 150 150 ASP ASP B . n 
B 1 151 PHE 151 151 151 PHE PHE B . n 
B 1 152 TYR 152 152 152 TYR TYR B . n 
B 1 153 GLU 153 153 153 GLU GLU B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 ALA 155 155 155 ALA ALA B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 TYR 157 157 157 TYR TYR B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 2DR   ? ? 2DR   ? ? 'SUBJECT OF INVESTIGATION' ? 
2 DCZ   ? ? DCZ   ? ? 'SUBJECT OF INVESTIGATION' ? 
3 A1H8P ? ? A1H8P ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 DCZ   1  201 201 DCZ   UNX A . 
D 3 A1H8P 1  202 202 A1H8P UNY A . 
E 4 2DR   1  201 201 2DR   UNL B . 
F 3 A1H8P 1  202 203 A1H8P UNY B . 
G 5 HOH   1  301 56  HOH   HOH A . 
G 5 HOH   2  302 22  HOH   HOH A . 
G 5 HOH   3  303 14  HOH   HOH A . 
G 5 HOH   4  304 26  HOH   HOH A . 
G 5 HOH   5  305 23  HOH   HOH A . 
G 5 HOH   6  306 28  HOH   HOH A . 
G 5 HOH   7  307 17  HOH   HOH A . 
G 5 HOH   8  308 21  HOH   HOH A . 
G 5 HOH   9  309 15  HOH   HOH A . 
G 5 HOH   10 310 19  HOH   HOH A . 
G 5 HOH   11 311 2   HOH   HOH A . 
G 5 HOH   12 312 58  HOH   HOH A . 
G 5 HOH   13 313 50  HOH   HOH A . 
G 5 HOH   14 314 47  HOH   HOH A . 
G 5 HOH   15 315 8   HOH   HOH A . 
G 5 HOH   16 316 44  HOH   HOH A . 
G 5 HOH   17 317 24  HOH   HOH A . 
G 5 HOH   18 318 20  HOH   HOH A . 
G 5 HOH   19 319 12  HOH   HOH A . 
G 5 HOH   20 320 53  HOH   HOH A . 
G 5 HOH   21 321 49  HOH   HOH A . 
G 5 HOH   22 322 4   HOH   HOH A . 
G 5 HOH   23 323 13  HOH   HOH A . 
G 5 HOH   24 324 29  HOH   HOH A . 
G 5 HOH   25 325 5   HOH   HOH A . 
G 5 HOH   26 326 39  HOH   HOH A . 
G 5 HOH   27 327 34  HOH   HOH A . 
G 5 HOH   28 328 31  HOH   HOH A . 
G 5 HOH   29 329 46  HOH   HOH A . 
G 5 HOH   30 330 57  HOH   HOH A . 
H 5 HOH   1  301 7   HOH   HOH B . 
H 5 HOH   2  302 32  HOH   HOH B . 
H 5 HOH   3  303 52  HOH   HOH B . 
H 5 HOH   4  304 40  HOH   HOH B . 
H 5 HOH   5  305 3   HOH   HOH B . 
H 5 HOH   6  306 48  HOH   HOH B . 
H 5 HOH   7  307 54  HOH   HOH B . 
H 5 HOH   8  308 10  HOH   HOH B . 
H 5 HOH   9  309 36  HOH   HOH B . 
H 5 HOH   10 310 11  HOH   HOH B . 
H 5 HOH   11 311 51  HOH   HOH B . 
H 5 HOH   12 312 18  HOH   HOH B . 
H 5 HOH   13 313 37  HOH   HOH B . 
H 5 HOH   14 314 55  HOH   HOH B . 
H 5 HOH   15 315 25  HOH   HOH B . 
H 5 HOH   16 316 6   HOH   HOH B . 
H 5 HOH   17 317 38  HOH   HOH B . 
H 5 HOH   18 318 16  HOH   HOH B . 
H 5 HOH   19 319 41  HOH   HOH B . 
H 5 HOH   20 320 30  HOH   HOH B . 
H 5 HOH   21 321 35  HOH   HOH B . 
H 5 HOH   22 322 33  HOH   HOH B . 
H 5 HOH   23 323 45  HOH   HOH B . 
H 5 HOH   24 324 42  HOH   HOH B . 
H 5 HOH   25 325 43  HOH   HOH B . 
H 5 HOH   26 326 27  HOH   HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 B MET 1   ? CG  ? B MET 1   CG  
2  1 Y 1 B MET 1   ? SD  ? B MET 1   SD  
3  1 Y 1 B MET 1   ? CE  ? B MET 1   CE  
4  1 Y 1 B LYS 22  ? CE  ? B LYS 22  CE  
5  1 Y 1 B LYS 22  ? NZ  ? B LYS 22  NZ  
6  1 Y 1 B LYS 29  ? CD  ? B LYS 29  CD  
7  1 Y 1 B LYS 29  ? CE  ? B LYS 29  CE  
8  1 Y 1 B LYS 29  ? NZ  ? B LYS 29  NZ  
9  1 Y 1 B GLU 30  ? CD  ? B GLU 30  CD  
10 1 Y 1 B GLU 30  ? OE1 ? B GLU 30  OE1 
11 1 Y 1 B GLU 30  ? OE2 ? B GLU 30  OE2 
12 1 Y 1 B LYS 48  ? CE  ? B LYS 48  CE  
13 1 Y 1 B LYS 48  ? NZ  ? B LYS 48  NZ  
14 1 Y 1 B ARG 51  ? CG  ? B ARG 51  CG  
15 1 Y 1 B ARG 51  ? CD  ? B ARG 51  CD  
16 1 Y 1 B ARG 51  ? NE  ? B ARG 51  NE  
17 1 Y 1 B ARG 51  ? CZ  ? B ARG 51  CZ  
18 1 Y 1 B ARG 51  ? NH1 ? B ARG 51  NH1 
19 1 Y 1 B ARG 51  ? NH2 ? B ARG 51  NH2 
20 1 Y 1 B GLU 54  ? CG  ? B GLU 54  CG  
21 1 Y 1 B GLU 54  ? CD  ? B GLU 54  CD  
22 1 Y 1 B GLU 54  ? OE1 ? B GLU 54  OE1 
23 1 Y 1 B GLU 54  ? OE2 ? B GLU 54  OE2 
24 1 Y 1 B LYS 140 ? NZ  ? B LYS 140 NZ  
25 1 Y 1 B GLU 153 ? CG  ? B GLU 153 CG  
26 1 Y 1 B GLU 153 ? CD  ? B GLU 153 CD  
27 1 Y 1 B GLU 153 ? OE1 ? B GLU 153 OE1 
28 1 Y 1 B GLU 153 ? OE2 ? B GLU 153 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALA  ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9F09 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     148.885 
_cell.length_a_esd                 ? 
_cell.length_b                     148.885 
_cell.length_b_esd                 ? 
_cell.length_c                     148.885 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        48 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9F09 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                199 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 21 3' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9F09 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.80 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          67.62 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M sodium citrate; 20% PEG 3350 pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     120 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-01-20 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976277 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976277 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          56 
_reflns.entry_id                                       9F09 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.37 
_reflns.d_resolution_low                               60.856 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     22441 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                41.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          33.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.02 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.00 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.09 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.37 
_reflns_shell.d_res_low                                     2.46 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           3.6 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2337 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               43.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.32 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.91 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.48 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.000 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.000 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.000 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               59.782 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.964 
_refine.correlation_coeff_Fo_to_Fc_free          0.951 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9F09 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.370 
_refine.ls_d_res_low                             60.856 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     22439 
_refine.ls_number_reflns_R_free                  1133 
_refine.ls_number_reflns_R_work                  21306 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.982 
_refine.ls_percent_reflns_R_free                 5.049 
_refine.ls_R_factor_all                          0.185 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2110 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1840 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.219 
_refine.pdbx_overall_ESU_R_Free                  0.179 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             6.086 
_refine.overall_SU_ML                            0.141 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        2524 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         44 
_refine_hist.number_atoms_solvent             56 
_refine_hist.number_atoms_total               2624 
_refine_hist.d_res_high                       2.370 
_refine_hist.d_res_low                        60.856 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  2638 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  2384 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.695  1.823  3582 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.605  1.765  5502 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.401  5.000  312  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 9.986  5.000  5    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 19.764 20.000 2    ? r_dihedral_angle_other_2_deg   ? ? 
'X-RAY DIFFRACTION' ? 14.849 10.000 418  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.034 10.000 130  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.094  0.200  371  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  3082 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  597  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.227  0.200  538  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.197  0.200  2167 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.191  0.200  1285 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.087  0.200  1349 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.243  0.200  67   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.442  0.200  2    ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.154  0.200  13   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.241  0.200  77   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.187  0.200  3    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 5.514  5.903  1254 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.494  5.902  1254 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 7.317  10.596 1564 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.315  10.596 1565 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 6.420  6.444  1384 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.419  6.444  1384 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 8.795  11.641 2018 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.793  11.641 2019 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 10.629 57.823 2971 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 10.628 57.825 2972 ? r_lrange_other                 ? ? 
'X-RAY DIFFRACTION' ? 0.082  0.050  5164 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.08194 ? 0.05009 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.08194 ? 0.05009 2 'Local ncs' ? A ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.370  2.432  1659 . 77 1580 99.8794  . 0.243 . . 0.240 . . . . . 0.209 . 20 . 0.969 0.941 0.315 
'X-RAY DIFFRACTION' 2.432  2.498  1605 . 80 1525 100.0000 . 0.232 . . 0.230 . . . . . 0.197 . 20 . 0.971 0.959 0.276 
'X-RAY DIFFRACTION' 2.498  2.570  1541 . 83 1458 100.0000 . 0.251 . . 0.247 . . . . . 0.211 . 20 . 0.969 0.946 0.311 
'X-RAY DIFFRACTION' 2.570  2.649  1514 . 53 1461 100.0000 . 0.227 . . 0.226 . . . . . 0.191 . 20 . 0.973 0.968 0.246 
'X-RAY DIFFRACTION' 2.649  2.736  1467 . 63 1404 100.0000 . 0.239 . . 0.235 . . . . . 0.200 . 20 . 0.971 0.936 0.338 
'X-RAY DIFFRACTION' 2.736  2.832  1410 . 65 1345 100.0000 . 0.214 . . 0.212 . . . . . 0.182 . 20 . 0.974 0.956 0.263 
'X-RAY DIFFRACTION' 2.832  2.939  1384 . 79 1305 100.0000 . 0.194 . . 0.193 . . . . . 0.168 . 20 . 0.976 0.972 0.212 
'X-RAY DIFFRACTION' 2.939  3.058  1328 . 60 1268 100.0000 . 0.205 . . 0.203 . . . . . 0.181 . 20 . 0.973 0.960 0.230 
'X-RAY DIFFRACTION' 3.058  3.194  1267 . 79 1188 100.0000 . 0.230 . . 0.228 . . . . . 0.207 . 20 . 0.968 0.957 0.262 
'X-RAY DIFFRACTION' 3.194  3.349  1193 . 63 1130 100.0000 . 0.214 . . 0.210 . . . . . 0.196 . 20 . 0.972 0.956 0.264 
'X-RAY DIFFRACTION' 3.349  3.530  1164 . 54 1110 100.0000 . 0.208 . . 0.207 . . . . . 0.194 . 20 . 0.977 0.971 0.236 
'X-RAY DIFFRACTION' 3.530  3.743  1102 . 48 1054 100.0000 . 0.192 . . 0.190 . . . . . 0.183 . 20 . 0.979 0.980 0.230 
'X-RAY DIFFRACTION' 3.743  4.001  1030 . 63 967  100.0000 . 0.178 . . 0.177 . . . . . 0.172 . 20 . 0.986 0.978 0.199 
'X-RAY DIFFRACTION' 4.001  4.320  970  . 53 917  100.0000 . 0.146 . . 0.145 . . . . . 0.142 . 20 . 0.989 0.987 0.152 
'X-RAY DIFFRACTION' 4.320  4.730  873  . 51 822  100.0000 . 0.131 . . 0.129 . . . . . 0.128 . 20 . 0.990 0.985 0.170 
'X-RAY DIFFRACTION' 4.730  5.284  828  . 47 781  100.0000 . 0.150 . . 0.152 . . . . . 0.150 . 20 . 0.987 0.991 0.132 
'X-RAY DIFFRACTION' 5.284  6.094  704  . 35 669  100.0000 . 0.182 . . 0.179 . . . . . 0.178 . 20 . 0.983 0.967 0.242 
'X-RAY DIFFRACTION' 6.094  7.444  624  . 31 593  100.0000 . 0.168 . . 0.167 . . . . . 0.168 . 20 . 0.984 0.976 0.196 
'X-RAY DIFFRACTION' 7.444  10.450 483  . 33 450  100.0000 . 0.147 . . 0.145 . . . . . 0.153 . 20 . 0.988 0.978 0.179 
'X-RAY DIFFRACTION' 10.450 60.856 295  . 16 279  100.0000 . 0.242 . . 0.242 . . . . . 0.252 . 20 . 0.962 0.969 0.238 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 A 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A MET 1 . A TYR 157 . A MET 1 A TYR 157 ? ? 
1 2 1 A MET 1 . A TYR 157 . A MET 1 A TYR 157 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9F09 
_struct.title                        
;Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Complex with 2-deoxyribose, 7-Bromo-1H-imidazo[4,5-b]pyridine and 2'-deoxycytidine
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9F09 
_struct_keywords.text            
;Nucleoside-2'-deoxyribosyltransferase, TRANSFERASE
;
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 3 ? 
G N N 5 ? 
H N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    NTD_LACLE 
_struct_ref.pdbx_db_accession          Q9R5V5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTND
IMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9F09 A 1 ? 157 ? Q9R5V5 1 ? 157 ? 1 157 
2 1 9F09 B 1 ? 157 ? Q9R5V5 1 ? 157 ? 1 157 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,C,D,E,F,G,H 
1 2 A,B,C,D,E,F,G,H 
1 3 A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
2 'crystal symmetry operation' 5_555 z,x,y 0.0000000000 0.0000000000 1.0000000000 0.0000000000 1.0000000000 0.0000000000 
0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 
3 'crystal symmetry operation' 9_555 y,z,x 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 
1.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 14  ? ASN A 31  ? THR A 14  ASN A 31  1 ? 18 
HELX_P HELX_P2  AA2 VAL A 41  ? ASN A 45  ? VAL A 41  ASN A 45  5 ? 5  
HELX_P HELX_P3  AA3 GLN A 46  ? ILE A 50  ? GLN A 46  ILE A 50  5 ? 5  
HELX_P HELX_P4  AA4 HIS A 55  ? HIS A 60  ? HIS A 55  HIS A 60  5 ? 6  
HELX_P HELX_P5  AA5 ASP A 61  ? THR A 78  ? ASP A 61  THR A 78  1 ? 18 
HELX_P HELX_P6  AA6 ASP A 92  ? GLN A 105 ? ASP A 92  GLN A 105 1 ? 14 
HELX_P HELX_P7  AA7 PRO A 114 ? TYR A 118 ? PRO A 114 TYR A 118 5 ? 5  
HELX_P HELX_P8  AA8 ASN A 123 ? SER A 130 ? ASN A 123 SER A 130 1 ? 8  
HELX_P HELX_P9  AA9 SER A 137 ? PHE A 142 ? SER A 137 PHE A 142 5 ? 6  
HELX_P HELX_P10 AB1 THR B 14  ? ASN B 31  ? THR B 14  ASN B 31  1 ? 18 
HELX_P HELX_P11 AB2 VAL B 41  ? ASN B 45  ? VAL B 41  ASN B 45  5 ? 5  
HELX_P HELX_P12 AB3 GLN B 46  ? ILE B 50  ? GLN B 46  ILE B 50  5 ? 5  
HELX_P HELX_P13 AB4 HIS B 55  ? HIS B 60  ? HIS B 55  HIS B 60  5 ? 6  
HELX_P HELX_P14 AB5 ASP B 61  ? THR B 78  ? ASP B 61  THR B 78  1 ? 18 
HELX_P HELX_P15 AB6 ASP B 92  ? GLN B 105 ? ASP B 92  GLN B 105 1 ? 14 
HELX_P HELX_P16 AB7 PRO B 114 ? TYR B 118 ? PRO B 114 TYR B 118 5 ? 5  
HELX_P HELX_P17 AB8 ASN B 123 ? SER B 130 ? ASN B 123 SER B 130 1 ? 8  
HELX_P HELX_P18 AB9 SER B 137 ? PHE B 142 ? SER B 137 PHE B 142 5 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        one 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           GLU 
_struct_conn.ptnr1_label_seq_id            98 
_struct_conn.ptnr1_label_atom_id           OE1 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           E 
_struct_conn.ptnr2_label_comp_id           2DR 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           C1 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            B 
_struct_conn.ptnr1_auth_comp_id            GLU 
_struct_conn.ptnr1_auth_seq_id             98 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            2DR 
_struct_conn.ptnr2_auth_seq_id             201 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.486 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      2DR 
_pdbx_modification_feature.label_asym_id                      E 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     GLU 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      98 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       2DR 
_pdbx_modification_feature.auth_asym_id                       B 
_pdbx_modification_feature.auth_seq_id                        201 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      GLU 
_pdbx_modification_feature.modified_residue_auth_asym_id      B 
_pdbx_modification_feature.modified_residue_auth_seq_id       98 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               C1 
_pdbx_modification_feature.modified_residue_id_linking_atom   OE1 
_pdbx_modification_feature.modified_residue_id                GLU 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        2DR 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           Carbohydrate 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 6   ? ALA A 10  ? ILE A 6   ALA A 10  
AA1 2 ILE A 81  ? VAL A 85  ? ILE A 81  VAL A 85  
AA1 3 TYR A 108 ? ILE A 113 ? TYR A 108 ILE A 113 
AA1 4 ASN A 132 ? LYS A 135 ? ASN A 132 LYS A 135 
AA2 1 ILE B 6   ? GLY B 9   ? ILE B 6   GLY B 9   
AA2 2 ILE B 81  ? VAL B 85  ? ILE B 81  VAL B 85  
AA2 3 TYR B 108 ? ILE B 113 ? TYR B 108 ILE B 113 
AA2 4 ASN B 132 ? LYS B 135 ? ASN B 132 LYS B 135 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 9   ? N GLY A 9   O VAL A 85  ? O VAL A 85  
AA1 2 3 N MET A 82  ? N MET A 82  O LEU A 110 ? O LEU A 110 
AA1 3 4 N LEU A 111 ? N LEU A 111 O ILE A 134 ? O ILE A 134 
AA2 1 2 N GLY B 9   ? N GLY B 9   O VAL B 85  ? O VAL B 85  
AA2 2 3 N MET B 82  ? N MET B 82  O LEU B 110 ? O LEU B 110 
AA2 3 4 N LEU B 111 ? N LEU B 111 O ILE B 134 ? O ILE B 134 
# 
_pdbx_entry_details.entry_id                   9F09 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OH 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   TYR 
_pdbx_validate_close_contact.auth_seq_id_1    58 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    301 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.00 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ALA A 10 ? ? -170.39 135.73 
2 1 PRO A 56 ? ? -63.69  0.76   
# 
_pdbx_validate_chiral.id              1 
_pdbx_validate_chiral.PDB_model_num   1 
_pdbx_validate_chiral.auth_atom_id    C1 
_pdbx_validate_chiral.label_alt_id    ? 
_pdbx_validate_chiral.auth_asym_id    B 
_pdbx_validate_chiral.auth_comp_id    2DR 
_pdbx_validate_chiral.auth_seq_id     201 
_pdbx_validate_chiral.PDB_ins_code    ? 
_pdbx_validate_chiral.details         'WRONG HAND' 
_pdbx_validate_chiral.omega           . 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    B 
_pdbx_validate_planes.auth_seq_id     148 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.088 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
2DR   C2     C  N N 1   
2DR   C3     C  N S 2   
2DR   C4     C  N R 3   
2DR   C5     C  N N 4   
2DR   O1     O  N N 5   
2DR   O3     O  N N 6   
2DR   O4     O  N N 7   
2DR   O5     O  N N 8   
2DR   C1     C  N R 9   
2DR   H2     H  N N 10  
2DR   H22C   H  N N 11  
2DR   H3     H  N N 12  
2DR   H1     H  N N 13  
2DR   H4     H  N N 14  
2DR   HO3    H  N N 15  
2DR   H51    H  N N 16  
2DR   H52    H  N N 17  
2DR   HO5    H  N N 18  
2DR   HO1    H  N N 19  
A1H8P C1     C  Y N 20  
A1H8P C2     C  Y N 21  
A1H8P C3     C  Y N 22  
A1H8P N1     N  Y N 23  
A1H8P C4     C  Y N 24  
A1H8P C5     C  Y N 25  
A1H8P C6     C  Y N 26  
A1H8P BR1    BR N N 27  
A1H8P N2     N  Y N 28  
A1H8P N3     N  Y N 29  
A1H8P H1     H  N N 30  
A1H8P H2     H  N N 31  
A1H8P H4     H  N N 32  
A1H8P H3     H  N N 33  
ALA   N      N  N N 34  
ALA   CA     C  N S 35  
ALA   C      C  N N 36  
ALA   O      O  N N 37  
ALA   CB     C  N N 38  
ALA   OXT    O  N N 39  
ALA   H      H  N N 40  
ALA   H2     H  N N 41  
ALA   HA     H  N N 42  
ALA   HB1    H  N N 43  
ALA   HB2    H  N N 44  
ALA   HB3    H  N N 45  
ALA   HXT    H  N N 46  
ARG   N      N  N N 47  
ARG   CA     C  N S 48  
ARG   C      C  N N 49  
ARG   O      O  N N 50  
ARG   CB     C  N N 51  
ARG   CG     C  N N 52  
ARG   CD     C  N N 53  
ARG   NE     N  N N 54  
ARG   CZ     C  N N 55  
ARG   NH1    N  N N 56  
ARG   NH2    N  N N 57  
ARG   OXT    O  N N 58  
ARG   H      H  N N 59  
ARG   H2     H  N N 60  
ARG   HA     H  N N 61  
ARG   HB2    H  N N 62  
ARG   HB3    H  N N 63  
ARG   HG2    H  N N 64  
ARG   HG3    H  N N 65  
ARG   HD2    H  N N 66  
ARG   HD3    H  N N 67  
ARG   HE     H  N N 68  
ARG   HH11   H  N N 69  
ARG   HH12   H  N N 70  
ARG   HH21   H  N N 71  
ARG   HH22   H  N N 72  
ARG   HXT    H  N N 73  
ASN   N      N  N N 74  
ASN   CA     C  N S 75  
ASN   C      C  N N 76  
ASN   O      O  N N 77  
ASN   CB     C  N N 78  
ASN   CG     C  N N 79  
ASN   OD1    O  N N 80  
ASN   ND2    N  N N 81  
ASN   OXT    O  N N 82  
ASN   H      H  N N 83  
ASN   H2     H  N N 84  
ASN   HA     H  N N 85  
ASN   HB2    H  N N 86  
ASN   HB3    H  N N 87  
ASN   HD21   H  N N 88  
ASN   HD22   H  N N 89  
ASN   HXT    H  N N 90  
ASP   N      N  N N 91  
ASP   CA     C  N S 92  
ASP   C      C  N N 93  
ASP   O      O  N N 94  
ASP   CB     C  N N 95  
ASP   CG     C  N N 96  
ASP   OD1    O  N N 97  
ASP   OD2    O  N N 98  
ASP   OXT    O  N N 99  
ASP   H      H  N N 100 
ASP   H2     H  N N 101 
ASP   HA     H  N N 102 
ASP   HB2    H  N N 103 
ASP   HB3    H  N N 104 
ASP   HD2    H  N N 105 
ASP   HXT    H  N N 106 
DCZ   N1     N  N N 107 
DCZ   C2     C  N N 108 
DCZ   N3     N  N N 109 
DCZ   C4     C  N N 110 
DCZ   C5     C  N N 111 
DCZ   C6     C  N N 112 
DCZ   O2     O  N N 113 
DCZ   N4     N  N N 114 
DCZ   "C1'"  C  N R 115 
DCZ   "C2'"  C  N N 116 
DCZ   "C3'"  C  N S 117 
DCZ   "C4'"  C  N R 118 
DCZ   "O4'"  O  N N 119 
DCZ   "O3'"  O  N N 120 
DCZ   "C5'"  C  N N 121 
DCZ   "O5'"  O  N N 122 
DCZ   H5     H  N N 123 
DCZ   H6     H  N N 124 
DCZ   HN41   H  N N 125 
DCZ   HN42   H  N N 126 
DCZ   "H1'"  H  N N 127 
DCZ   "H2'1" H  N N 128 
DCZ   "H2'2" H  N N 129 
DCZ   "H3'"  H  N N 130 
DCZ   "H4'"  H  N N 131 
DCZ   "HO3'" H  N N 132 
DCZ   "H5'1" H  N N 133 
DCZ   "H5'2" H  N N 134 
DCZ   HO51   H  N N 135 
GLN   N      N  N N 136 
GLN   CA     C  N S 137 
GLN   C      C  N N 138 
GLN   O      O  N N 139 
GLN   CB     C  N N 140 
GLN   CG     C  N N 141 
GLN   CD     C  N N 142 
GLN   OE1    O  N N 143 
GLN   NE2    N  N N 144 
GLN   OXT    O  N N 145 
GLN   H      H  N N 146 
GLN   H2     H  N N 147 
GLN   HA     H  N N 148 
GLN   HB2    H  N N 149 
GLN   HB3    H  N N 150 
GLN   HG2    H  N N 151 
GLN   HG3    H  N N 152 
GLN   HE21   H  N N 153 
GLN   HE22   H  N N 154 
GLN   HXT    H  N N 155 
GLU   N      N  N N 156 
GLU   CA     C  N S 157 
GLU   C      C  N N 158 
GLU   O      O  N N 159 
GLU   CB     C  N N 160 
GLU   CG     C  N N 161 
GLU   CD     C  N N 162 
GLU   OE1    O  N N 163 
GLU   OE2    O  N N 164 
GLU   OXT    O  N N 165 
GLU   H      H  N N 166 
GLU   H2     H  N N 167 
GLU   HA     H  N N 168 
GLU   HB2    H  N N 169 
GLU   HB3    H  N N 170 
GLU   HG2    H  N N 171 
GLU   HG3    H  N N 172 
GLU   HE2    H  N N 173 
GLU   HXT    H  N N 174 
GLY   N      N  N N 175 
GLY   CA     C  N N 176 
GLY   C      C  N N 177 
GLY   O      O  N N 178 
GLY   OXT    O  N N 179 
GLY   H      H  N N 180 
GLY   H2     H  N N 181 
GLY   HA2    H  N N 182 
GLY   HA3    H  N N 183 
GLY   HXT    H  N N 184 
HIS   N      N  N N 185 
HIS   CA     C  N S 186 
HIS   C      C  N N 187 
HIS   O      O  N N 188 
HIS   CB     C  N N 189 
HIS   CG     C  Y N 190 
HIS   ND1    N  Y N 191 
HIS   CD2    C  Y N 192 
HIS   CE1    C  Y N 193 
HIS   NE2    N  Y N 194 
HIS   OXT    O  N N 195 
HIS   H      H  N N 196 
HIS   H2     H  N N 197 
HIS   HA     H  N N 198 
HIS   HB2    H  N N 199 
HIS   HB3    H  N N 200 
HIS   HD1    H  N N 201 
HIS   HD2    H  N N 202 
HIS   HE1    H  N N 203 
HIS   HE2    H  N N 204 
HIS   HXT    H  N N 205 
HOH   O      O  N N 206 
HOH   H1     H  N N 207 
HOH   H2     H  N N 208 
ILE   N      N  N N 209 
ILE   CA     C  N S 210 
ILE   C      C  N N 211 
ILE   O      O  N N 212 
ILE   CB     C  N S 213 
ILE   CG1    C  N N 214 
ILE   CG2    C  N N 215 
ILE   CD1    C  N N 216 
ILE   OXT    O  N N 217 
ILE   H      H  N N 218 
ILE   H2     H  N N 219 
ILE   HA     H  N N 220 
ILE   HB     H  N N 221 
ILE   HG12   H  N N 222 
ILE   HG13   H  N N 223 
ILE   HG21   H  N N 224 
ILE   HG22   H  N N 225 
ILE   HG23   H  N N 226 
ILE   HD11   H  N N 227 
ILE   HD12   H  N N 228 
ILE   HD13   H  N N 229 
ILE   HXT    H  N N 230 
LEU   N      N  N N 231 
LEU   CA     C  N S 232 
LEU   C      C  N N 233 
LEU   O      O  N N 234 
LEU   CB     C  N N 235 
LEU   CG     C  N N 236 
LEU   CD1    C  N N 237 
LEU   CD2    C  N N 238 
LEU   OXT    O  N N 239 
LEU   H      H  N N 240 
LEU   H2     H  N N 241 
LEU   HA     H  N N 242 
LEU   HB2    H  N N 243 
LEU   HB3    H  N N 244 
LEU   HG     H  N N 245 
LEU   HD11   H  N N 246 
LEU   HD12   H  N N 247 
LEU   HD13   H  N N 248 
LEU   HD21   H  N N 249 
LEU   HD22   H  N N 250 
LEU   HD23   H  N N 251 
LEU   HXT    H  N N 252 
LYS   N      N  N N 253 
LYS   CA     C  N S 254 
LYS   C      C  N N 255 
LYS   O      O  N N 256 
LYS   CB     C  N N 257 
LYS   CG     C  N N 258 
LYS   CD     C  N N 259 
LYS   CE     C  N N 260 
LYS   NZ     N  N N 261 
LYS   OXT    O  N N 262 
LYS   H      H  N N 263 
LYS   H2     H  N N 264 
LYS   HA     H  N N 265 
LYS   HB2    H  N N 266 
LYS   HB3    H  N N 267 
LYS   HG2    H  N N 268 
LYS   HG3    H  N N 269 
LYS   HD2    H  N N 270 
LYS   HD3    H  N N 271 
LYS   HE2    H  N N 272 
LYS   HE3    H  N N 273 
LYS   HZ1    H  N N 274 
LYS   HZ2    H  N N 275 
LYS   HZ3    H  N N 276 
LYS   HXT    H  N N 277 
MET   N      N  N N 278 
MET   CA     C  N S 279 
MET   C      C  N N 280 
MET   O      O  N N 281 
MET   CB     C  N N 282 
MET   CG     C  N N 283 
MET   SD     S  N N 284 
MET   CE     C  N N 285 
MET   OXT    O  N N 286 
MET   H      H  N N 287 
MET   H2     H  N N 288 
MET   HA     H  N N 289 
MET   HB2    H  N N 290 
MET   HB3    H  N N 291 
MET   HG2    H  N N 292 
MET   HG3    H  N N 293 
MET   HE1    H  N N 294 
MET   HE2    H  N N 295 
MET   HE3    H  N N 296 
MET   HXT    H  N N 297 
PHE   N      N  N N 298 
PHE   CA     C  N S 299 
PHE   C      C  N N 300 
PHE   O      O  N N 301 
PHE   CB     C  N N 302 
PHE   CG     C  Y N 303 
PHE   CD1    C  Y N 304 
PHE   CD2    C  Y N 305 
PHE   CE1    C  Y N 306 
PHE   CE2    C  Y N 307 
PHE   CZ     C  Y N 308 
PHE   OXT    O  N N 309 
PHE   H      H  N N 310 
PHE   H2     H  N N 311 
PHE   HA     H  N N 312 
PHE   HB2    H  N N 313 
PHE   HB3    H  N N 314 
PHE   HD1    H  N N 315 
PHE   HD2    H  N N 316 
PHE   HE1    H  N N 317 
PHE   HE2    H  N N 318 
PHE   HZ     H  N N 319 
PHE   HXT    H  N N 320 
PRO   N      N  N N 321 
PRO   CA     C  N S 322 
PRO   C      C  N N 323 
PRO   O      O  N N 324 
PRO   CB     C  N N 325 
PRO   CG     C  N N 326 
PRO   CD     C  N N 327 
PRO   OXT    O  N N 328 
PRO   H      H  N N 329 
PRO   HA     H  N N 330 
PRO   HB2    H  N N 331 
PRO   HB3    H  N N 332 
PRO   HG2    H  N N 333 
PRO   HG3    H  N N 334 
PRO   HD2    H  N N 335 
PRO   HD3    H  N N 336 
PRO   HXT    H  N N 337 
SER   N      N  N N 338 
SER   CA     C  N S 339 
SER   C      C  N N 340 
SER   O      O  N N 341 
SER   CB     C  N N 342 
SER   OG     O  N N 343 
SER   OXT    O  N N 344 
SER   H      H  N N 345 
SER   H2     H  N N 346 
SER   HA     H  N N 347 
SER   HB2    H  N N 348 
SER   HB3    H  N N 349 
SER   HG     H  N N 350 
SER   HXT    H  N N 351 
THR   N      N  N N 352 
THR   CA     C  N S 353 
THR   C      C  N N 354 
THR   O      O  N N 355 
THR   CB     C  N R 356 
THR   OG1    O  N N 357 
THR   CG2    C  N N 358 
THR   OXT    O  N N 359 
THR   H      H  N N 360 
THR   H2     H  N N 361 
THR   HA     H  N N 362 
THR   HB     H  N N 363 
THR   HG1    H  N N 364 
THR   HG21   H  N N 365 
THR   HG22   H  N N 366 
THR   HG23   H  N N 367 
THR   HXT    H  N N 368 
TRP   N      N  N N 369 
TRP   CA     C  N S 370 
TRP   C      C  N N 371 
TRP   O      O  N N 372 
TRP   CB     C  N N 373 
TRP   CG     C  Y N 374 
TRP   CD1    C  Y N 375 
TRP   CD2    C  Y N 376 
TRP   NE1    N  Y N 377 
TRP   CE2    C  Y N 378 
TRP   CE3    C  Y N 379 
TRP   CZ2    C  Y N 380 
TRP   CZ3    C  Y N 381 
TRP   CH2    C  Y N 382 
TRP   OXT    O  N N 383 
TRP   H      H  N N 384 
TRP   H2     H  N N 385 
TRP   HA     H  N N 386 
TRP   HB2    H  N N 387 
TRP   HB3    H  N N 388 
TRP   HD1    H  N N 389 
TRP   HE1    H  N N 390 
TRP   HE3    H  N N 391 
TRP   HZ2    H  N N 392 
TRP   HZ3    H  N N 393 
TRP   HH2    H  N N 394 
TRP   HXT    H  N N 395 
TYR   N      N  N N 396 
TYR   CA     C  N S 397 
TYR   C      C  N N 398 
TYR   O      O  N N 399 
TYR   CB     C  N N 400 
TYR   CG     C  Y N 401 
TYR   CD1    C  Y N 402 
TYR   CD2    C  Y N 403 
TYR   CE1    C  Y N 404 
TYR   CE2    C  Y N 405 
TYR   CZ     C  Y N 406 
TYR   OH     O  N N 407 
TYR   OXT    O  N N 408 
TYR   H      H  N N 409 
TYR   H2     H  N N 410 
TYR   HA     H  N N 411 
TYR   HB2    H  N N 412 
TYR   HB3    H  N N 413 
TYR   HD1    H  N N 414 
TYR   HD2    H  N N 415 
TYR   HE1    H  N N 416 
TYR   HE2    H  N N 417 
TYR   HH     H  N N 418 
TYR   HXT    H  N N 419 
VAL   N      N  N N 420 
VAL   CA     C  N S 421 
VAL   C      C  N N 422 
VAL   O      O  N N 423 
VAL   CB     C  N N 424 
VAL   CG1    C  N N 425 
VAL   CG2    C  N N 426 
VAL   OXT    O  N N 427 
VAL   H      H  N N 428 
VAL   H2     H  N N 429 
VAL   HA     H  N N 430 
VAL   HB     H  N N 431 
VAL   HG11   H  N N 432 
VAL   HG12   H  N N 433 
VAL   HG13   H  N N 434 
VAL   HG21   H  N N 435 
VAL   HG22   H  N N 436 
VAL   HG23   H  N N 437 
VAL   HXT    H  N N 438 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
2DR   C2    C3     sing N N 1   
2DR   C2    C1     sing N N 2   
2DR   C3    C4     sing N N 3   
2DR   C3    O3     sing N N 4   
2DR   C4    C5     sing N N 5   
2DR   C4    O4     sing N N 6   
2DR   C5    O5     sing N N 7   
2DR   O1    C1     sing N N 8   
2DR   O4    C1     sing N N 9   
2DR   C2    H2     sing N N 10  
2DR   C2    H22C   sing N N 11  
2DR   C3    H3     sing N N 12  
2DR   C1    H1     sing N N 13  
2DR   C4    H4     sing N N 14  
2DR   O3    HO3    sing N N 15  
2DR   C5    H51    sing N N 16  
2DR   C5    H52    sing N N 17  
2DR   O5    HO5    sing N N 18  
2DR   O1    HO1    sing N N 19  
A1H8P BR1   C1     sing N N 20  
A1H8P C1    C2     doub Y N 21  
A1H8P C2    C3     sing Y N 22  
A1H8P C3    N1     doub Y N 23  
A1H8P N1    C4     sing Y N 24  
A1H8P C4    N2     sing Y N 25  
A1H8P N2    C5     sing Y N 26  
A1H8P C5    N3     doub Y N 27  
A1H8P N3    C6     sing Y N 28  
A1H8P C1    C6     sing Y N 29  
A1H8P C4    C6     doub Y N 30  
A1H8P C2    H1     sing N N 31  
A1H8P C3    H2     sing N N 32  
A1H8P C5    H4     sing N N 33  
A1H8P N2    H3     sing N N 34  
ALA   N     CA     sing N N 35  
ALA   N     H      sing N N 36  
ALA   N     H2     sing N N 37  
ALA   CA    C      sing N N 38  
ALA   CA    CB     sing N N 39  
ALA   CA    HA     sing N N 40  
ALA   C     O      doub N N 41  
ALA   C     OXT    sing N N 42  
ALA   CB    HB1    sing N N 43  
ALA   CB    HB2    sing N N 44  
ALA   CB    HB3    sing N N 45  
ALA   OXT   HXT    sing N N 46  
ARG   N     CA     sing N N 47  
ARG   N     H      sing N N 48  
ARG   N     H2     sing N N 49  
ARG   CA    C      sing N N 50  
ARG   CA    CB     sing N N 51  
ARG   CA    HA     sing N N 52  
ARG   C     O      doub N N 53  
ARG   C     OXT    sing N N 54  
ARG   CB    CG     sing N N 55  
ARG   CB    HB2    sing N N 56  
ARG   CB    HB3    sing N N 57  
ARG   CG    CD     sing N N 58  
ARG   CG    HG2    sing N N 59  
ARG   CG    HG3    sing N N 60  
ARG   CD    NE     sing N N 61  
ARG   CD    HD2    sing N N 62  
ARG   CD    HD3    sing N N 63  
ARG   NE    CZ     sing N N 64  
ARG   NE    HE     sing N N 65  
ARG   CZ    NH1    sing N N 66  
ARG   CZ    NH2    doub N N 67  
ARG   NH1   HH11   sing N N 68  
ARG   NH1   HH12   sing N N 69  
ARG   NH2   HH21   sing N N 70  
ARG   NH2   HH22   sing N N 71  
ARG   OXT   HXT    sing N N 72  
ASN   N     CA     sing N N 73  
ASN   N     H      sing N N 74  
ASN   N     H2     sing N N 75  
ASN   CA    C      sing N N 76  
ASN   CA    CB     sing N N 77  
ASN   CA    HA     sing N N 78  
ASN   C     O      doub N N 79  
ASN   C     OXT    sing N N 80  
ASN   CB    CG     sing N N 81  
ASN   CB    HB2    sing N N 82  
ASN   CB    HB3    sing N N 83  
ASN   CG    OD1    doub N N 84  
ASN   CG    ND2    sing N N 85  
ASN   ND2   HD21   sing N N 86  
ASN   ND2   HD22   sing N N 87  
ASN   OXT   HXT    sing N N 88  
ASP   N     CA     sing N N 89  
ASP   N     H      sing N N 90  
ASP   N     H2     sing N N 91  
ASP   CA    C      sing N N 92  
ASP   CA    CB     sing N N 93  
ASP   CA    HA     sing N N 94  
ASP   C     O      doub N N 95  
ASP   C     OXT    sing N N 96  
ASP   CB    CG     sing N N 97  
ASP   CB    HB2    sing N N 98  
ASP   CB    HB3    sing N N 99  
ASP   CG    OD1    doub N N 100 
ASP   CG    OD2    sing N N 101 
ASP   OD2   HD2    sing N N 102 
ASP   OXT   HXT    sing N N 103 
DCZ   N1    C2     sing N N 104 
DCZ   N1    C6     sing N N 105 
DCZ   N1    "C1'"  sing N N 106 
DCZ   C2    N3     sing N N 107 
DCZ   C2    O2     doub N N 108 
DCZ   N3    C4     doub N N 109 
DCZ   C4    C5     sing N N 110 
DCZ   C4    N4     sing N N 111 
DCZ   C5    C6     doub N N 112 
DCZ   C5    H5     sing N N 113 
DCZ   C6    H6     sing N N 114 
DCZ   N4    HN41   sing N N 115 
DCZ   N4    HN42   sing N N 116 
DCZ   "C1'" "C2'"  sing N N 117 
DCZ   "C1'" "O4'"  sing N N 118 
DCZ   "C1'" "H1'"  sing N N 119 
DCZ   "C2'" "C3'"  sing N N 120 
DCZ   "C2'" "H2'1" sing N N 121 
DCZ   "C2'" "H2'2" sing N N 122 
DCZ   "C3'" "C4'"  sing N N 123 
DCZ   "C3'" "O3'"  sing N N 124 
DCZ   "C3'" "H3'"  sing N N 125 
DCZ   "C4'" "O4'"  sing N N 126 
DCZ   "C4'" "C5'"  sing N N 127 
DCZ   "C4'" "H4'"  sing N N 128 
DCZ   "O3'" "HO3'" sing N N 129 
DCZ   "C5'" "O5'"  sing N N 130 
DCZ   "C5'" "H5'1" sing N N 131 
DCZ   "C5'" "H5'2" sing N N 132 
DCZ   "O5'" HO51   sing N N 133 
GLN   N     CA     sing N N 134 
GLN   N     H      sing N N 135 
GLN   N     H2     sing N N 136 
GLN   CA    C      sing N N 137 
GLN   CA    CB     sing N N 138 
GLN   CA    HA     sing N N 139 
GLN   C     O      doub N N 140 
GLN   C     OXT    sing N N 141 
GLN   CB    CG     sing N N 142 
GLN   CB    HB2    sing N N 143 
GLN   CB    HB3    sing N N 144 
GLN   CG    CD     sing N N 145 
GLN   CG    HG2    sing N N 146 
GLN   CG    HG3    sing N N 147 
GLN   CD    OE1    doub N N 148 
GLN   CD    NE2    sing N N 149 
GLN   NE2   HE21   sing N N 150 
GLN   NE2   HE22   sing N N 151 
GLN   OXT   HXT    sing N N 152 
GLU   N     CA     sing N N 153 
GLU   N     H      sing N N 154 
GLU   N     H2     sing N N 155 
GLU   CA    C      sing N N 156 
GLU   CA    CB     sing N N 157 
GLU   CA    HA     sing N N 158 
GLU   C     O      doub N N 159 
GLU   C     OXT    sing N N 160 
GLU   CB    CG     sing N N 161 
GLU   CB    HB2    sing N N 162 
GLU   CB    HB3    sing N N 163 
GLU   CG    CD     sing N N 164 
GLU   CG    HG2    sing N N 165 
GLU   CG    HG3    sing N N 166 
GLU   CD    OE1    doub N N 167 
GLU   CD    OE2    sing N N 168 
GLU   OE2   HE2    sing N N 169 
GLU   OXT   HXT    sing N N 170 
GLY   N     CA     sing N N 171 
GLY   N     H      sing N N 172 
GLY   N     H2     sing N N 173 
GLY   CA    C      sing N N 174 
GLY   CA    HA2    sing N N 175 
GLY   CA    HA3    sing N N 176 
GLY   C     O      doub N N 177 
GLY   C     OXT    sing N N 178 
GLY   OXT   HXT    sing N N 179 
HIS   N     CA     sing N N 180 
HIS   N     H      sing N N 181 
HIS   N     H2     sing N N 182 
HIS   CA    C      sing N N 183 
HIS   CA    CB     sing N N 184 
HIS   CA    HA     sing N N 185 
HIS   C     O      doub N N 186 
HIS   C     OXT    sing N N 187 
HIS   CB    CG     sing N N 188 
HIS   CB    HB2    sing N N 189 
HIS   CB    HB3    sing N N 190 
HIS   CG    ND1    sing Y N 191 
HIS   CG    CD2    doub Y N 192 
HIS   ND1   CE1    doub Y N 193 
HIS   ND1   HD1    sing N N 194 
HIS   CD2   NE2    sing Y N 195 
HIS   CD2   HD2    sing N N 196 
HIS   CE1   NE2    sing Y N 197 
HIS   CE1   HE1    sing N N 198 
HIS   NE2   HE2    sing N N 199 
HIS   OXT   HXT    sing N N 200 
HOH   O     H1     sing N N 201 
HOH   O     H2     sing N N 202 
ILE   N     CA     sing N N 203 
ILE   N     H      sing N N 204 
ILE   N     H2     sing N N 205 
ILE   CA    C      sing N N 206 
ILE   CA    CB     sing N N 207 
ILE   CA    HA     sing N N 208 
ILE   C     O      doub N N 209 
ILE   C     OXT    sing N N 210 
ILE   CB    CG1    sing N N 211 
ILE   CB    CG2    sing N N 212 
ILE   CB    HB     sing N N 213 
ILE   CG1   CD1    sing N N 214 
ILE   CG1   HG12   sing N N 215 
ILE   CG1   HG13   sing N N 216 
ILE   CG2   HG21   sing N N 217 
ILE   CG2   HG22   sing N N 218 
ILE   CG2   HG23   sing N N 219 
ILE   CD1   HD11   sing N N 220 
ILE   CD1   HD12   sing N N 221 
ILE   CD1   HD13   sing N N 222 
ILE   OXT   HXT    sing N N 223 
LEU   N     CA     sing N N 224 
LEU   N     H      sing N N 225 
LEU   N     H2     sing N N 226 
LEU   CA    C      sing N N 227 
LEU   CA    CB     sing N N 228 
LEU   CA    HA     sing N N 229 
LEU   C     O      doub N N 230 
LEU   C     OXT    sing N N 231 
LEU   CB    CG     sing N N 232 
LEU   CB    HB2    sing N N 233 
LEU   CB    HB3    sing N N 234 
LEU   CG    CD1    sing N N 235 
LEU   CG    CD2    sing N N 236 
LEU   CG    HG     sing N N 237 
LEU   CD1   HD11   sing N N 238 
LEU   CD1   HD12   sing N N 239 
LEU   CD1   HD13   sing N N 240 
LEU   CD2   HD21   sing N N 241 
LEU   CD2   HD22   sing N N 242 
LEU   CD2   HD23   sing N N 243 
LEU   OXT   HXT    sing N N 244 
LYS   N     CA     sing N N 245 
LYS   N     H      sing N N 246 
LYS   N     H2     sing N N 247 
LYS   CA    C      sing N N 248 
LYS   CA    CB     sing N N 249 
LYS   CA    HA     sing N N 250 
LYS   C     O      doub N N 251 
LYS   C     OXT    sing N N 252 
LYS   CB    CG     sing N N 253 
LYS   CB    HB2    sing N N 254 
LYS   CB    HB3    sing N N 255 
LYS   CG    CD     sing N N 256 
LYS   CG    HG2    sing N N 257 
LYS   CG    HG3    sing N N 258 
LYS   CD    CE     sing N N 259 
LYS   CD    HD2    sing N N 260 
LYS   CD    HD3    sing N N 261 
LYS   CE    NZ     sing N N 262 
LYS   CE    HE2    sing N N 263 
LYS   CE    HE3    sing N N 264 
LYS   NZ    HZ1    sing N N 265 
LYS   NZ    HZ2    sing N N 266 
LYS   NZ    HZ3    sing N N 267 
LYS   OXT   HXT    sing N N 268 
MET   N     CA     sing N N 269 
MET   N     H      sing N N 270 
MET   N     H2     sing N N 271 
MET   CA    C      sing N N 272 
MET   CA    CB     sing N N 273 
MET   CA    HA     sing N N 274 
MET   C     O      doub N N 275 
MET   C     OXT    sing N N 276 
MET   CB    CG     sing N N 277 
MET   CB    HB2    sing N N 278 
MET   CB    HB3    sing N N 279 
MET   CG    SD     sing N N 280 
MET   CG    HG2    sing N N 281 
MET   CG    HG3    sing N N 282 
MET   SD    CE     sing N N 283 
MET   CE    HE1    sing N N 284 
MET   CE    HE2    sing N N 285 
MET   CE    HE3    sing N N 286 
MET   OXT   HXT    sing N N 287 
PHE   N     CA     sing N N 288 
PHE   N     H      sing N N 289 
PHE   N     H2     sing N N 290 
PHE   CA    C      sing N N 291 
PHE   CA    CB     sing N N 292 
PHE   CA    HA     sing N N 293 
PHE   C     O      doub N N 294 
PHE   C     OXT    sing N N 295 
PHE   CB    CG     sing N N 296 
PHE   CB    HB2    sing N N 297 
PHE   CB    HB3    sing N N 298 
PHE   CG    CD1    doub Y N 299 
PHE   CG    CD2    sing Y N 300 
PHE   CD1   CE1    sing Y N 301 
PHE   CD1   HD1    sing N N 302 
PHE   CD2   CE2    doub Y N 303 
PHE   CD2   HD2    sing N N 304 
PHE   CE1   CZ     doub Y N 305 
PHE   CE1   HE1    sing N N 306 
PHE   CE2   CZ     sing Y N 307 
PHE   CE2   HE2    sing N N 308 
PHE   CZ    HZ     sing N N 309 
PHE   OXT   HXT    sing N N 310 
PRO   N     CA     sing N N 311 
PRO   N     CD     sing N N 312 
PRO   N     H      sing N N 313 
PRO   CA    C      sing N N 314 
PRO   CA    CB     sing N N 315 
PRO   CA    HA     sing N N 316 
PRO   C     O      doub N N 317 
PRO   C     OXT    sing N N 318 
PRO   CB    CG     sing N N 319 
PRO   CB    HB2    sing N N 320 
PRO   CB    HB3    sing N N 321 
PRO   CG    CD     sing N N 322 
PRO   CG    HG2    sing N N 323 
PRO   CG    HG3    sing N N 324 
PRO   CD    HD2    sing N N 325 
PRO   CD    HD3    sing N N 326 
PRO   OXT   HXT    sing N N 327 
SER   N     CA     sing N N 328 
SER   N     H      sing N N 329 
SER   N     H2     sing N N 330 
SER   CA    C      sing N N 331 
SER   CA    CB     sing N N 332 
SER   CA    HA     sing N N 333 
SER   C     O      doub N N 334 
SER   C     OXT    sing N N 335 
SER   CB    OG     sing N N 336 
SER   CB    HB2    sing N N 337 
SER   CB    HB3    sing N N 338 
SER   OG    HG     sing N N 339 
SER   OXT   HXT    sing N N 340 
THR   N     CA     sing N N 341 
THR   N     H      sing N N 342 
THR   N     H2     sing N N 343 
THR   CA    C      sing N N 344 
THR   CA    CB     sing N N 345 
THR   CA    HA     sing N N 346 
THR   C     O      doub N N 347 
THR   C     OXT    sing N N 348 
THR   CB    OG1    sing N N 349 
THR   CB    CG2    sing N N 350 
THR   CB    HB     sing N N 351 
THR   OG1   HG1    sing N N 352 
THR   CG2   HG21   sing N N 353 
THR   CG2   HG22   sing N N 354 
THR   CG2   HG23   sing N N 355 
THR   OXT   HXT    sing N N 356 
TRP   N     CA     sing N N 357 
TRP   N     H      sing N N 358 
TRP   N     H2     sing N N 359 
TRP   CA    C      sing N N 360 
TRP   CA    CB     sing N N 361 
TRP   CA    HA     sing N N 362 
TRP   C     O      doub N N 363 
TRP   C     OXT    sing N N 364 
TRP   CB    CG     sing N N 365 
TRP   CB    HB2    sing N N 366 
TRP   CB    HB3    sing N N 367 
TRP   CG    CD1    doub Y N 368 
TRP   CG    CD2    sing Y N 369 
TRP   CD1   NE1    sing Y N 370 
TRP   CD1   HD1    sing N N 371 
TRP   CD2   CE2    doub Y N 372 
TRP   CD2   CE3    sing Y N 373 
TRP   NE1   CE2    sing Y N 374 
TRP   NE1   HE1    sing N N 375 
TRP   CE2   CZ2    sing Y N 376 
TRP   CE3   CZ3    doub Y N 377 
TRP   CE3   HE3    sing N N 378 
TRP   CZ2   CH2    doub Y N 379 
TRP   CZ2   HZ2    sing N N 380 
TRP   CZ3   CH2    sing Y N 381 
TRP   CZ3   HZ3    sing N N 382 
TRP   CH2   HH2    sing N N 383 
TRP   OXT   HXT    sing N N 384 
TYR   N     CA     sing N N 385 
TYR   N     H      sing N N 386 
TYR   N     H2     sing N N 387 
TYR   CA    C      sing N N 388 
TYR   CA    CB     sing N N 389 
TYR   CA    HA     sing N N 390 
TYR   C     O      doub N N 391 
TYR   C     OXT    sing N N 392 
TYR   CB    CG     sing N N 393 
TYR   CB    HB2    sing N N 394 
TYR   CB    HB3    sing N N 395 
TYR   CG    CD1    doub Y N 396 
TYR   CG    CD2    sing Y N 397 
TYR   CD1   CE1    sing Y N 398 
TYR   CD1   HD1    sing N N 399 
TYR   CD2   CE2    doub Y N 400 
TYR   CD2   HD2    sing N N 401 
TYR   CE1   CZ     doub Y N 402 
TYR   CE1   HE1    sing N N 403 
TYR   CE2   CZ     sing Y N 404 
TYR   CE2   HE2    sing N N 405 
TYR   CZ    OH     sing N N 406 
TYR   OH    HH     sing N N 407 
TYR   OXT   HXT    sing N N 408 
VAL   N     CA     sing N N 409 
VAL   N     H      sing N N 410 
VAL   N     H2     sing N N 411 
VAL   CA    C      sing N N 412 
VAL   CA    CB     sing N N 413 
VAL   CA    HA     sing N N 414 
VAL   C     O      doub N N 415 
VAL   C     OXT    sing N N 416 
VAL   CB    CG1    sing N N 417 
VAL   CB    CG2    sing N N 418 
VAL   CB    HB     sing N N 419 
VAL   CG1   HG11   sing N N 420 
VAL   CG1   HG12   sing N N 421 
VAL   CG1   HG13   sing N N 422 
VAL   CG2   HG21   sing N N 423 
VAL   CG2   HG22   sing N N 424 
VAL   CG2   HG23   sing N N 425 
VAL   OXT   HXT    sing N N 426 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1F8Y 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9F09 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006717 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006717 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006717 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 0.4386   
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H  1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0487   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N  N     . MET   A 1 1   ? 21.206  31.907  20.103  1.000 97.366  0 1   MET   A N     1 ? 
ATOM   2    C  CA    . MET   A 1 1   ? 22.169  31.138  20.944  1.000 91.982  0 1   MET   A CA    1 ? 
ATOM   3    C  C     . MET   A 1 1   ? 22.006  29.631  20.698  1.000 79.890  0 1   MET   A C     1 ? 
ATOM   4    O  O     . MET   A 1 1   ? 23.006  28.924  20.605  1.000 75.868  0 1   MET   A O     1 ? 
ATOM   5    C  CB    . MET   A 1 1   ? 22.039  31.504  22.433  1.000 91.480  0 1   MET   A CB    1 ? 
ATOM   6    C  CG    . MET   A 1 1   ? 23.023  30.773  23.338  1.000 102.815 0 1   MET   A CG    1 ? 
ATOM   7    S  SD    . MET   A 1 1   ? 22.698  30.974  25.104  1.000 130.664 0 1   MET   A SD    1 ? 
ATOM   8    C  CE    . MET   A 1 1   ? 23.027  32.701  25.496  1.000 117.799 0 1   MET   A CE    1 ? 
ATOM   9    N  N     . PRO   A 1 2   ? 20.780  29.052  20.638  1.000 63.989  0 2   PRO   A N     1 ? 
ATOM   10   C  CA    . PRO   A 1 2   ? 20.602  27.734  20.025  1.000 58.879  0 2   PRO   A CA    1 ? 
ATOM   11   C  C     . PRO   A 1 2   ? 20.894  27.840  18.526  1.000 53.785  0 2   PRO   A C     1 ? 
ATOM   12   O  O     . PRO   A 1 2   ? 20.585  28.850  17.891  1.000 50.502  0 2   PRO   A O     1 ? 
ATOM   13   C  CB    . PRO   A 1 2   ? 19.145  27.305  20.322  1.000 52.630  0 2   PRO   A CB    1 ? 
ATOM   14   C  CG    . PRO   A 1 2   ? 18.651  28.310  21.347  1.000 58.482  0 2   PRO   A CG    1 ? 
ATOM   15   C  CD    . PRO   A 1 2   ? 19.529  29.570  21.215  1.000 59.150  0 2   PRO   A CD    1 ? 
ATOM   16   N  N     . LYS   A 1 3   ? 21.517  26.797  17.978  1.000 51.897  0 3   LYS   A N     1 ? 
ATOM   17   C  CA    . LYS   A 1 3   ? 21.926  26.757  16.586  1.000 59.425  0 3   LYS   A CA    1 ? 
ATOM   18   C  C     . LYS   A 1 3   ? 21.392  25.481  15.940  1.000 58.437  0 3   LYS   A C     1 ? 
ATOM   19   O  O     . LYS   A 1 3   ? 21.314  24.441  16.580  1.000 48.715  0 3   LYS   A O     1 ? 
ATOM   20   C  CB    . LYS   A 1 3   ? 23.453  26.803  16.502  1.000 58.690  0 3   LYS   A CB    1 ? 
ATOM   21   C  CG    . LYS   A 1 3   ? 24.094  28.164  16.764  1.000 63.620  0 3   LYS   A CG    1 ? 
ATOM   22   C  CD    . LYS   A 1 3   ? 25.591  28.066  17.057  1.000 73.545  0 3   LYS   A CD    1 ? 
ATOM   23   C  CE    . LYS   A 1 3   ? 26.344  29.361  17.124  1.000 74.372  0 3   LYS   A CE    1 ? 
ATOM   24   N  NZ    . LYS   A 1 3   ? 26.751  29.737  15.769  1.000 84.302  0 3   LYS   A NZ    1 ? 
ATOM   25   N  N     . LYS   A 1 4   ? 21.065  25.560  14.646  1.000 56.287  0 4   LYS   A N     1 ? 
ATOM   26   C  CA    . LYS   A 1 4   ? 20.617  24.409  13.883  1.000 51.000  0 4   LYS   A CA    1 ? 
ATOM   27   C  C     . LYS   A 1 4   ? 21.644  24.079  12.802  1.000 49.672  0 4   LYS   A C     1 ? 
ATOM   28   O  O     . LYS   A 1 4   ? 22.313  24.983  12.304  1.000 51.763  0 4   LYS   A O     1 ? 
ATOM   29   C  CB    . LYS   A 1 4   ? 19.305  24.776  13.189  1.000 50.244  0 4   LYS   A CB    1 ? 
ATOM   30   C  CG    . LYS   A 1 4   ? 18.140  25.124  14.105  1.000 53.093  0 4   LYS   A CG    1 ? 
ATOM   31   C  CD    . LYS   A 1 4   ? 17.482  23.907  14.731  1.000 53.699  0 4   LYS   A CD    1 ? 
ATOM   32   C  CE    . LYS   A 1 4   ? 16.301  24.140  15.600  1.000 61.677  0 4   LYS   A CE    1 ? 
ATOM   33   N  NZ    . LYS   A 1 4   ? 16.816  24.549  16.907  1.000 71.501  0 4   LYS   A NZ    1 ? 
ATOM   34   N  N     . THR   A 1 5   ? 21.677  22.815  12.367  1.000 41.347  0 5   THR   A N     1 ? 
ATOM   35   C  CA    . THR   A 1 5   ? 22.506  22.420  11.242  1.000 45.013  0 5   THR   A CA    1 ? 
ATOM   36   C  C     . THR   A 1 5   ? 21.629  22.310  10.012  1.000 46.003  0 5   THR   A C     1 ? 
ATOM   37   O  O     . THR   A 1 5   ? 20.414  22.135  10.126  1.000 45.106  0 5   THR   A O     1 ? 
ATOM   38   C  CB    . THR   A 1 5   ? 23.227  21.095  11.526  1.000 47.536  0 5   THR   A CB    1 ? 
ATOM   39   O  OG1   . THR   A 1 5   ? 22.230  20.094  11.726  1.000 45.400  0 5   THR   A OG1   1 ? 
ATOM   40   C  CG2   . THR   A 1 5   ? 24.096  21.178  12.767  1.000 44.687  0 5   THR   A CG2   1 ? 
ATOM   41   N  N     . ILE   A 1 6   ? 22.271  22.381  8.843   1.000 46.974  0 6   ILE   A N     1 ? 
ATOM   42   C  CA    . ILE   A 1 6   ? 21.526  22.296  7.594   1.000 45.192  0 6   ILE   A CA    1 ? 
ATOM   43   C  C     . ILE   A 1 6   ? 22.193  21.315  6.640   1.000 43.827  0 6   ILE   A C     1 ? 
ATOM   44   O  O     . ILE   A 1 6   ? 23.331  20.896  6.828   1.000 48.090  0 6   ILE   A O     1 ? 
ATOM   45   C  CB    . ILE   A 1 6   ? 21.338  23.672  6.929   1.000 50.732  0 6   ILE   A CB    1 ? 
ATOM   46   C  CG1   . ILE   A 1 6   ? 22.640  24.382  6.683   1.000 52.430  0 6   ILE   A CG1   1 ? 
ATOM   47   C  CG2   . ILE   A 1 6   ? 20.395  24.550  7.736   1.000 54.762  0 6   ILE   A CG2   1 ? 
ATOM   48   C  CD1   . ILE   A 1 6   ? 23.207  24.131  5.315   1.000 53.723  0 6   ILE   A CD1   1 ? 
ATOM   49   N  N     . TYR   A 1 7   ? 21.396  20.897  5.659   1.000 45.767  0 7   TYR   A N     1 ? 
ATOM   50   C  CA    . TYR   A 1 7   ? 21.881  20.280  4.441   1.000 49.481  0 7   TYR   A CA    1 ? 
ATOM   51   C  C     . TYR   A 1 7   ? 21.872  21.351  3.361   1.000 40.045  0 7   TYR   A C     1 ? 
ATOM   52   O  O     . TYR   A 1 7   ? 20.833  21.946  3.110   1.000 46.723  0 7   TYR   A O     1 ? 
ATOM   53   C  CB    . TYR   A 1 7   ? 20.977  19.094  4.067   1.000 46.736  0 7   TYR   A CB    1 ? 
ATOM   54   C  CG    . TYR   A 1 7   ? 21.347  18.385  2.774   1.000 47.308  0 7   TYR   A CG    1 ? 
ATOM   55   C  CD1   . TYR   A 1 7   ? 20.850  18.804  1.545   1.000 44.548  0 7   TYR   A CD1   1 ? 
ATOM   56   C  CD2   . TYR   A 1 7   ? 22.166  17.263  2.786   1.000 43.819  0 7   TYR   A CD2   1 ? 
ATOM   57   C  CE1   . TYR   A 1 7   ? 21.189  18.148  0.374   1.000 45.148  0 7   TYR   A CE1   1 ? 
ATOM   58   C  CE2   . TYR   A 1 7   ? 22.485  16.588  1.616   1.000 48.384  0 7   TYR   A CE2   1 ? 
ATOM   59   C  CZ    . TYR   A 1 7   ? 22.008  17.033  0.405   1.000 48.724  0 7   TYR   A CZ    1 ? 
ATOM   60   O  OH    . TYR   A 1 7   ? 22.368  16.336  -0.715  1.000 55.552  0 7   TYR   A OH    1 ? 
ATOM   61   N  N     . PHE   A 1 8   ? 23.027  21.553  2.727   1.000 47.352  0 8   PHE   A N     1 ? 
ATOM   62   C  CA    . PHE   A 1 8   ? 23.215  22.576  1.716   1.000 46.022  0 8   PHE   A CA    1 ? 
ATOM   63   C  C     . PHE   A 1 8   ? 22.788  22.049  0.359   1.000 48.646  0 8   PHE   A C     1 ? 
ATOM   64   O  O     . PHE   A 1 8   ? 23.628  21.628  -0.440  1.000 49.624  0 8   PHE   A O     1 ? 
ATOM   65   C  CB    . PHE   A 1 8   ? 24.679  23.012  1.693   1.000 48.879  0 8   PHE   A CB    1 ? 
ATOM   66   C  CG    . PHE   A 1 8   ? 24.874  24.332  0.971   1.000 48.640  0 8   PHE   A CG    1 ? 
ATOM   67   C  CD1   . PHE   A 1 8   ? 24.620  25.529  1.620   1.000 51.275  0 8   PHE   A CD1   1 ? 
ATOM   68   C  CD2   . PHE   A 1 8   ? 25.284  24.364  -0.359  1.000 49.402  0 8   PHE   A CD2   1 ? 
ATOM   69   C  CE1   . PHE   A 1 8   ? 24.779  26.730  0.955   1.000 56.156  0 8   PHE   A CE1   1 ? 
ATOM   70   C  CE2   . PHE   A 1 8   ? 25.447  25.567  -1.017  1.000 53.091  0 8   PHE   A CE2   1 ? 
ATOM   71   C  CZ    . PHE   A 1 8   ? 25.194  26.746  -0.361  1.000 53.386  0 8   PHE   A CZ    1 ? 
ATOM   72   N  N     . GLY   A 1 9   ? 21.483  22.105  0.096   1.000 44.096  0 9   GLY   A N     1 ? 
ATOM   73   C  CA    . GLY   A 1 9   ? 20.981  21.671  -1.195  1.000 45.675  0 9   GLY   A CA    1 ? 
ATOM   74   C  C     . GLY   A 1 9   ? 21.169  22.772  -2.236  1.000 48.026  0 9   GLY   A C     1 ? 
ATOM   75   O  O     . GLY   A 1 9   ? 20.675  23.896  -2.073  1.000 46.768  0 9   GLY   A O     1 ? 
ATOM   76   N  N     . ALA   A 1 10  ? 21.898  22.443  -3.299  1.000 49.079  0 10  ALA   A N     1 ? 
ATOM   77   C  CA    . ALA   A 1 10  ? 22.204  23.414  -4.343  1.000 44.459  0 10  ALA   A CA    1 ? 
ATOM   78   C  C     . ALA   A 1 10  ? 22.837  22.715  -5.530  1.000 53.565  0 10  ALA   A C     1 ? 
ATOM   79   O  O     . ALA   A 1 10  ? 23.740  21.908  -5.352  1.000 48.597  0 10  ALA   A O     1 ? 
ATOM   80   C  CB    . ALA   A 1 10  ? 23.173  24.448  -3.852  1.000 44.958  0 10  ALA   A CB    1 ? 
ATOM   81   N  N     . GLY   A 1 11  ? 22.395  23.067  -6.734  1.000 54.915  0 11  GLY   A N     1 ? 
ATOM   82   C  CA    . GLY   A 1 11  ? 23.141  22.699  -7.919  1.000 54.775  0 11  GLY   A CA    1 ? 
ATOM   83   C  C     . GLY   A 1 11  ? 24.472  23.449  -8.003  1.000 55.386  0 11  GLY   A C     1 ? 
ATOM   84   O  O     . GLY   A 1 11  ? 24.627  24.526  -7.420  1.000 50.685  0 11  GLY   A O     1 ? 
ATOM   85   N  N     . TRP   A 1 12  ? 25.409  22.879  -8.782  1.000 51.552  0 12  TRP   A N     1 ? 
ATOM   86   C  CA    . TRP   A 1 12  ? 26.684  23.510  -9.041  1.000 54.626  0 12  TRP   A CA    1 ? 
ATOM   87   C  C     . TRP   A 1 12  ? 27.064  23.356  -10.507 1.000 59.054  0 12  TRP   A C     1 ? 
ATOM   88   O  O     . TRP   A 1 12  ? 28.254  23.210  -10.801 1.000 53.963  0 12  TRP   A O     1 ? 
ATOM   89   C  CB    . TRP   A 1 12  ? 27.760  22.941  -8.114  1.000 52.255  0 12  TRP   A CB    1 ? 
ATOM   90   C  CG    . TRP   A 1 12  ? 27.919  21.449  -8.192  1.000 61.588  0 12  TRP   A CG    1 ? 
ATOM   91   C  CD1   . TRP   A 1 12  ? 28.621  20.750  -9.126  1.000 59.867  0 12  TRP   A CD1   1 ? 
ATOM   92   C  CD2   . TRP   A 1 12  ? 27.434  20.481  -7.239  1.000 60.355  0 12  TRP   A CD2   1 ? 
ATOM   93   N  NE1   . TRP   A 1 12  ? 28.550  19.414  -8.856  1.000 65.045  0 12  TRP   A NE1   1 ? 
ATOM   94   C  CE2   . TRP   A 1 12  ? 27.866  19.218  -7.689  1.000 58.269  0 12  TRP   A CE2   1 ? 
ATOM   95   C  CE3   . TRP   A 1 12  ? 26.693  20.563  -6.056  1.000 54.954  0 12  TRP   A CE3   1 ? 
ATOM   96   C  CZ2   . TRP   A 1 12  ? 27.566  18.047  -7.003  1.000 64.923  0 12  TRP   A CZ2   1 ? 
ATOM   97   C  CZ3   . TRP   A 1 12  ? 26.432  19.413  -5.354  1.000 62.055  0 12  TRP   A CZ3   1 ? 
ATOM   98   C  CH2   . TRP   A 1 12  ? 26.860  18.168  -5.824  1.000 66.273  0 12  TRP   A CH2   1 ? 
ATOM   99   N  N     . PHE   A 1 13  ? 26.053  23.448  -11.397 1.000 56.346  0 13  PHE   A N     1 ? 
ATOM   100  C  CA    . PHE   A 1 13  ? 26.198  23.036  -12.789 1.000 62.100  0 13  PHE   A CA    1 ? 
ATOM   101  C  C     . PHE   A 1 13  ? 26.078  24.194  -13.782 1.000 69.044  0 13  PHE   A C     1 ? 
ATOM   102  O  O     . PHE   A 1 13  ? 26.159  23.933  -14.980 1.000 65.766  0 13  PHE   A O     1 ? 
ATOM   103  C  CB    . PHE   A 1 13  ? 25.130  22.005  -13.173 1.000 56.757  0 13  PHE   A CB    1 ? 
ATOM   104  C  CG    . PHE   A 1 13  ? 25.017  20.873  -12.166 1.000 63.366  0 13  PHE   A CG    1 ? 
ATOM   105  C  CD1   . PHE   A 1 13  ? 26.072  19.974  -11.984 1.000 60.076  0 13  PHE   A CD1   1 ? 
ATOM   106  C  CD2   . PHE   A 1 13  ? 23.861  20.715  -11.406 1.000 57.943  0 13  PHE   A CD2   1 ? 
ATOM   107  C  CE1   . PHE   A 1 13  ? 25.991  18.986  -11.026 1.000 59.231  0 13  PHE   A CE1   1 ? 
ATOM   108  C  CE2   . PHE   A 1 13  ? 23.787  19.715  -10.454 1.000 58.159  0 13  PHE   A CE2   1 ? 
ATOM   109  C  CZ    . PHE   A 1 13  ? 24.847  18.856  -10.265 1.000 60.294  0 13  PHE   A CZ    1 ? 
ATOM   110  N  N     . THR   A 1 14  ? 25.834  25.428  -13.304 1.000 68.609  0 14  THR   A N     1 ? 
ATOM   111  C  CA    . THR   A 1 14  ? 25.742  26.619  -14.146 1.000 59.474  0 14  THR   A CA    1 ? 
ATOM   112  C  C     . THR   A 1 14  ? 26.371  27.797  -13.410 1.000 65.151  0 14  THR   A C     1 ? 
ATOM   113  O  O     . THR   A 1 14  ? 26.652  27.711  -12.215 1.000 64.441  0 14  THR   A O     1 ? 
ATOM   114  C  CB    . THR   A 1 14  ? 24.301  26.974  -14.530 1.000 58.141  0 14  THR   A CB    1 ? 
ATOM   115  O  OG1   . THR   A 1 14  ? 23.686  27.419  -13.333 1.000 57.427  0 14  THR   A OG1   1 ? 
ATOM   116  C  CG2   . THR   A 1 14  ? 23.465  25.824  -15.060 1.000 61.220  0 14  THR   A CG2   1 ? 
ATOM   117  N  N     . ASP   A 1 15  ? 26.581  28.906  -14.134 1.000 63.422  0 15  ASP   A N     1 ? 
ATOM   118  C  CA    . ASP   A 1 15  ? 27.207  30.085  -13.555 1.000 64.333  0 15  ASP   A CA    1 ? 
ATOM   119  C  C     . ASP   A 1 15  ? 26.268  30.722  -12.533 1.000 60.737  0 15  ASP   A C     1 ? 
ATOM   120  O  O     . ASP   A 1 15  ? 26.736  31.199  -11.508 1.000 58.645  0 15  ASP   A O     1 ? 
ATOM   121  C  CB    . ASP   A 1 15  ? 27.639  31.102  -14.606 1.000 69.084  0 15  ASP   A CB    1 ? 
ATOM   122  C  CG    . ASP   A 1 15  ? 28.713  30.617  -15.575 1.000 75.937  0 15  ASP   A CG    1 ? 
ATOM   123  O  OD1   . ASP   A 1 15  ? 29.592  29.830  -15.158 1.000 74.585  0 15  ASP   A OD1   1 ? 
ATOM   124  O  OD2   . ASP   A 1 15  ? 28.679  31.054  -16.737 1.000 75.703  0 15  ASP   A OD2   1 ? 
ATOM   125  N  N     . ARG   A 1 16  ? 24.955  30.721  -12.804 1.000 54.651  0 16  ARG   A N     1 ? 
ATOM   126  C  CA    . ARG   A 1 16  ? 24.010  31.291  -11.861 1.000 58.032  0 16  ARG   A CA    1 ? 
ATOM   127  C  C     . ARG   A 1 16  ? 23.903  30.406  -10.625 1.000 54.925  0 16  ARG   A C     1 ? 
ATOM   128  O  O     . ARG   A 1 16  ? 23.876  30.927  -9.511  1.000 56.742  0 16  ARG   A O     1 ? 
ATOM   129  C  CB    . ARG   A 1 16  ? 22.660  31.563  -12.516 1.000 63.269  0 16  ARG   A CB    1 ? 
ATOM   130  C  CG    . ARG   A 1 16  ? 22.839  32.616  -13.596 1.000 65.747  0 16  ARG   A CG    1 ? 
ATOM   131  C  CD    . ARG   A 1 16  ? 21.660  32.593  -14.549 1.000 63.950  0 16  ARG   A CD    1 ? 
ATOM   132  N  NE    . ARG   A 1 16  ? 20.526  33.136  -13.812 1.000 62.074  0 16  ARG   A NE    1 ? 
ATOM   133  C  CZ    . ARG   A 1 16  ? 19.302  33.120  -14.260 1.000 63.148  0 16  ARG   A CZ    1 ? 
ATOM   134  N  NH1   . ARG   A 1 16  ? 19.056  32.572  -15.438 1.000 66.004  0 16  ARG   A NH1   1 ? 
ATOM   135  N  NH2   . ARG   A 1 16  ? 18.350  33.641  -13.507 1.000 65.183  0 16  ARG   A NH2   1 ? 
ATOM   136  N  N     . GLN   A 1 17  ? 23.952  29.085  -10.822 1.000 50.410  0 17  GLN   A N     1 ? 
ATOM   137  C  CA    . GLN   A 1 17  ? 23.934  28.145  -9.713  1.000 53.459  0 17  GLN   A CA    1 ? 
ATOM   138  C  C     . GLN   A 1 17  ? 25.137  28.396  -8.809  1.000 52.976  0 17  GLN   A C     1 ? 
ATOM   139  O  O     . GLN   A 1 17  ? 24.977  28.489  -7.598  1.000 53.873  0 17  GLN   A O     1 ? 
ATOM   140  C  CB    . GLN   A 1 17  ? 23.856  26.686  -10.163 1.000 53.408  0 17  GLN   A CB    1 ? 
ATOM   141  C  CG    . GLN   A 1 17  ? 22.453  26.291  -10.610 1.000 49.931  0 17  GLN   A CG    1 ? 
ATOM   142  C  CD    . GLN   A 1 17  ? 22.358  24.872  -11.123 1.000 52.811  0 17  GLN   A CD    1 ? 
ATOM   143  O  OE1   . GLN   A 1 17  ? 23.313  24.094  -11.049 1.000 60.709  0 17  GLN   A OE1   1 ? 
ATOM   144  N  NE2   . GLN   A 1 17  ? 21.194  24.523  -11.663 1.000 55.934  0 17  GLN   A NE2   1 ? 
ATOM   145  N  N     . ASN   A 1 18  ? 26.317  28.552  -9.406  1.000 53.898  0 18  ASN   A N     1 ? 
ATOM   146  C  CA    . ASN   A 1 18  ? 27.539  28.677  -8.631  1.000 55.873  0 18  ASN   A CA    1 ? 
ATOM   147  C  C     . ASN   A 1 18  ? 27.563  30.031  -7.927  1.000 56.427  0 18  ASN   A C     1 ? 
ATOM   148  O  O     . ASN   A 1 18  ? 28.024  30.148  -6.791  1.000 53.734  0 18  ASN   A O     1 ? 
ATOM   149  C  CB    . ASN   A 1 18  ? 28.787  28.457  -9.488  1.000 58.825  0 18  ASN   A CB    1 ? 
ATOM   150  C  CG    . ASN   A 1 18  ? 28.986  27.004  -9.818  1.000 59.945  0 18  ASN   A CG    1 ? 
ATOM   151  O  OD1   . ASN   A 1 18  ? 28.892  26.156  -8.932  1.000 61.521  0 18  ASN   A OD1   1 ? 
ATOM   152  N  ND2   . ASN   A 1 18  ? 29.209  26.694  -11.080 1.000 63.422  0 18  ASN   A ND2   1 ? 
ATOM   153  N  N     . LYS   A 1 19  ? 27.032  31.059  -8.586  1.000 57.263  0 19  LYS   A N     1 ? 
ATOM   154  C  CA    . LYS   A 1 19  ? 26.973  32.367  -7.960  1.000 60.173  0 19  LYS   A CA    1 ? 
ATOM   155  C  C     . LYS   A 1 19  ? 26.085  32.287  -6.708  1.000 57.417  0 19  LYS   A C     1 ? 
ATOM   156  O  O     . LYS   A 1 19  ? 26.474  32.749  -5.627  1.000 56.431  0 19  LYS   A O     1 ? 
ATOM   157  C  CB    . LYS   A 1 19  ? 26.500  33.427  -8.961  1.000 63.326  0 19  LYS   A CB    1 ? 
ATOM   158  C  CG    . LYS   A 1 19  ? 26.536  34.850  -8.379  1.000 69.855  0 19  LYS   A CG    1 ? 
ATOM   159  C  CD    . LYS   A 1 19  ? 26.056  35.980  -9.277  1.000 76.693  0 19  LYS   A CD    1 ? 
ATOM   160  C  CE    . LYS   A 1 19  ? 26.494  37.295  -8.686  1.000 84.163  0 19  LYS   A CE    1 ? 
ATOM   161  N  NZ    . LYS   A 1 19  ? 25.852  38.438  -9.340  1.000 87.593  0 19  LYS   A NZ    1 ? 
ATOM   162  N  N     . ALA   A 1 20  ? 24.888  31.706  -6.863  1.000 53.449  0 20  ALA   A N     1 ? 
ATOM   163  C  CA    . ALA   A 1 20  ? 23.922  31.641  -5.775  1.000 51.413  0 20  ALA   A CA    1 ? 
ATOM   164  C  C     . ALA   A 1 20  ? 24.464  30.783  -4.634  1.000 46.232  0 20  ALA   A C     1 ? 
ATOM   165  O  O     . ALA   A 1 20  ? 24.294  31.108  -3.464  1.000 50.430  0 20  ALA   A O     1 ? 
ATOM   166  C  CB    . ALA   A 1 20  ? 22.610  31.124  -6.299  1.000 54.542  0 20  ALA   A CB    1 ? 
ATOM   167  N  N     . TYR   A 1 21  ? 25.182  29.726  -5.000  1.000 47.102  0 21  TYR   A N     1 ? 
ATOM   168  C  CA    . TYR   A 1 21  ? 25.805  28.832  -4.048  1.000 49.147  0 21  TYR   A CA    1 ? 
ATOM   169  C  C     . TYR   A 1 21  ? 26.759  29.633  -3.163  1.000 54.341  0 21  TYR   A C     1 ? 
ATOM   170  O  O     . TYR   A 1 21  ? 26.726  29.478  -1.942  1.000 51.303  0 21  TYR   A O     1 ? 
ATOM   171  C  CB    . TYR   A 1 21  ? 26.448  27.736  -4.911  1.000 49.968  0 21  TYR   A CB    1 ? 
ATOM   172  C  CG    . TYR   A 1 21  ? 27.185  26.625  -4.179  1.000 54.533  0 21  TYR   A CG    1 ? 
ATOM   173  C  CD1   . TYR   A 1 21  ? 28.189  26.887  -3.258  1.000 51.688  0 21  TYR   A CD1   1 ? 
ATOM   174  C  CD2   . TYR   A 1 21  ? 26.851  25.293  -4.400  1.000 56.477  0 21  TYR   A CD2   1 ? 
ATOM   175  C  CE1   . TYR   A 1 21  ? 28.822  25.862  -2.564  1.000 53.830  0 21  TYR   A CE1   1 ? 
ATOM   176  C  CE2   . TYR   A 1 21  ? 27.479  24.260  -3.721  1.000 51.752  0 21  TYR   A CE2   1 ? 
ATOM   177  C  CZ    . TYR   A 1 21  ? 28.472  24.545  -2.805  1.000 53.610  0 21  TYR   A CZ    1 ? 
ATOM   178  O  OH    . TYR   A 1 21  ? 29.092  23.509  -2.169  1.000 49.512  0 21  TYR   A OH    1 ? 
ATOM   179  N  N     . LYS   A 1 22  ? 27.628  30.453  -3.785  1.000 56.830  0 22  LYS   A N     1 ? 
ATOM   180  C  CA    . LYS   A 1 22  ? 28.665  31.178  -3.057  1.000 56.700  0 22  LYS   A CA    1 ? 
ATOM   181  C  C     . LYS   A 1 22  ? 27.992  32.171  -2.117  1.000 52.297  0 22  LYS   A C     1 ? 
ATOM   182  O  O     . LYS   A 1 22  ? 28.362  32.268  -0.942  1.000 52.387  0 22  LYS   A O     1 ? 
ATOM   183  C  CB    . LYS   A 1 22  ? 29.684  31.922  -3.930  1.000 69.643  0 22  LYS   A CB    1 ? 
ATOM   184  C  CG    . LYS   A 1 22  ? 31.020  31.242  -4.226  1.000 93.155  0 22  LYS   A CG    1 ? 
ATOM   185  C  CD    . LYS   A 1 22  ? 32.013  32.090  -5.027  1.000 110.359 0 22  LYS   A CD    1 ? 
ATOM   186  C  CE    . LYS   A 1 22  ? 31.643  32.285  -6.478  1.000 113.842 0 22  LYS   A CE    1 ? 
ATOM   187  N  NZ    . LYS   A 1 22  ? 31.545  31.018  -7.217  1.000 105.239 0 22  LYS   A NZ    1 ? 
ATOM   188  N  N     . GLU   A 1 23  ? 26.959  32.850  -2.634  1.000 54.426  0 23  GLU   A N     1 ? 
ATOM   189  C  CA    . GLU   A 1 23  ? 26.205  33.823  -1.855  1.000 53.356  0 23  GLU   A CA    1 ? 
ATOM   190  C  C     . GLU   A 1 23  ? 25.537  33.172  -0.638  1.000 57.255  0 23  GLU   A C     1 ? 
ATOM   191  O  O     . GLU   A 1 23  ? 25.586  33.707  0.464   1.000 54.022  0 23  GLU   A O     1 ? 
ATOM   192  C  CB    . GLU   A 1 23  ? 25.168  34.492  -2.751  1.000 54.458  0 23  GLU   A CB    1 ? 
ATOM   193  C  CG    . GLU   A 1 23  ? 25.764  35.487  -3.744  1.000 59.253  0 23  GLU   A CG    1 ? 
ATOM   194  C  CD    . GLU   A 1 23  ? 24.726  36.199  -4.621  1.000 71.660  0 23  GLU   A CD    1 ? 
ATOM   195  O  OE1   . GLU   A 1 23  ? 25.137  37.284  -5.106  1.000 69.746  0 23  GLU   A OE1   1 ? 
ATOM   196  O  OE2   . GLU   A 1 23  ? 23.560  35.723  -4.849  1.000 65.037  0 23  GLU   A OE2   1 ? 
ATOM   197  N  N     . ALA   A 1 24  ? 24.900  32.013  -0.844  1.000 53.641  0 24  ALA   A N     1 ? 
ATOM   198  C  CA    . ALA   A 1 24  ? 24.175  31.348  0.226   1.000 55.114  0 24  ALA   A CA    1 ? 
ATOM   199  C  C     . ALA   A 1 24  ? 25.135  30.881  1.316   1.000 48.852  0 24  ALA   A C     1 ? 
ATOM   200  O  O     . ALA   A 1 24  ? 24.838  30.973  2.510   1.000 53.174  0 24  ALA   A O     1 ? 
ATOM   201  C  CB    . ALA   A 1 24  ? 23.371  30.193  -0.329  1.000 58.509  0 24  ALA   A CB    1 ? 
ATOM   202  N  N     . MET   A 1 25  ? 26.301  30.391  0.906   1.000 50.709  0 25  MET   A N     1 ? 
ATOM   203  C  CA    . MET   A 1 25  ? 27.289  29.924  1.867   1.000 52.336  0 25  MET   A CA    1 ? 
ATOM   204  C  C     . MET   A 1 25  ? 27.756  31.105  2.722   1.000 57.325  0 25  MET   A C     1 ? 
ATOM   205  O  O     . MET   A 1 25  ? 27.829  30.982  3.939   1.000 63.411  0 25  MET   A O     1 ? 
ATOM   206  C  CB    . MET   A 1 25  ? 28.459  29.234  1.163   1.000 50.167  0 25  MET   A CB    1 ? 
ATOM   207  C  CG    . MET   A 1 25  ? 29.250  28.300  2.060   1.000 65.225  0 25  MET   A CG    1 ? 
ATOM   208  S  SD    . MET   A 1 25  ? 28.357  26.846  2.656   1.000 61.012  0 25  MET   A SD    1 ? 
ATOM   209  C  CE    . MET   A 1 25  ? 28.359  25.729  1.252   1.000 61.082  0 25  MET   A CE    1 ? 
ATOM   210  N  N     . GLU   A 1 26  ? 28.016  32.265  2.104   1.000 60.918  0 26  GLU   A N     1 ? 
ATOM   211  C  CA    . GLU   A 1 26  ? 28.419  33.461  2.846   1.000 65.576  0 26  GLU   A CA    1 ? 
ATOM   212  C  C     . GLU   A 1 26  ? 27.320  33.907  3.816   1.000 56.482  0 26  GLU   A C     1 ? 
ATOM   213  O  O     . GLU   A 1 26  ? 27.615  34.277  4.951   1.000 58.478  0 26  GLU   A O     1 ? 
ATOM   214  C  CB    . GLU   A 1 26  ? 28.844  34.615  1.930   1.000 72.039  0 26  GLU   A CB    1 ? 
ATOM   215  C  CG    . GLU   A 1 26  ? 30.287  34.480  1.435   1.000 83.969  0 26  GLU   A CG    1 ? 
ATOM   216  C  CD    . GLU   A 1 26  ? 30.664  35.243  0.162   1.000 106.628 0 26  GLU   A CD    1 ? 
ATOM   217  O  OE1   . GLU   A 1 26  ? 29.796  35.562  -0.689  1.000 101.035 0 26  GLU   A OE1   1 ? 
ATOM   218  O  OE2   . GLU   A 1 26  ? 31.873  35.539  0.018   1.000 122.134 0 26  GLU   A OE2   1 ? 
ATOM   219  N  N     . ALA   A 1 27  ? 26.050  33.871  3.380   1.000 53.608  0 27  ALA   A N     1 ? 
ATOM   220  C  CA    . ALA   A 1 27  ? 24.950  34.209  4.267   1.000 51.191  0 27  ALA   A CA    1 ? 
ATOM   221  C  C     . ALA   A 1 27  ? 24.921  33.290  5.492   1.000 56.105  0 27  ALA   A C     1 ? 
ATOM   222  O  O     . ALA   A 1 27  ? 24.779  33.773  6.622   1.000 50.047  0 27  ALA   A O     1 ? 
ATOM   223  C  CB    . ALA   A 1 27  ? 23.637  34.164  3.536   1.000 52.894  0 27  ALA   A CB    1 ? 
ATOM   224  N  N     . LEU   A 1 28  ? 25.108  31.978  5.271   1.000 52.810  0 28  LEU   A N     1 ? 
ATOM   225  C  CA    . LEU   A 1 28  ? 25.091  31.022  6.364   1.000 51.857  0 28  LEU   A CA    1 ? 
ATOM   226  C  C     . LEU   A 1 28  ? 26.219  31.285  7.364   1.000 53.729  0 28  LEU   A C     1 ? 
ATOM   227  O  O     . LEU   A 1 28  ? 25.994  31.144  8.567   1.000 57.297  0 28  LEU   A O     1 ? 
ATOM   228  C  CB    . LEU   A 1 28  ? 25.118  29.582  5.858   1.000 51.511  0 28  LEU   A CB    1 ? 
ATOM   229  C  CG    . LEU   A 1 28  ? 23.865  29.137  5.107   1.000 48.931  0 28  LEU   A CG    1 ? 
ATOM   230  C  CD1   . LEU   A 1 28  ? 24.152  27.818  4.456   1.000 52.018  0 28  LEU   A CD1   1 ? 
ATOM   231  C  CD2   . LEU   A 1 28  ? 22.636  29.047  5.998   1.000 50.860  0 28  LEU   A CD2   1 ? 
ATOM   232  N  N     . LYS   A 1 29  ? 27.418  31.651  6.890   1.000 54.859  0 29  LYS   A N     1 ? 
ATOM   233  C  CA    . LYS   A 1 29  ? 28.520  31.947  7.792   1.000 57.916  0 29  LYS   A CA    1 ? 
ATOM   234  C  C     . LYS   A 1 29  ? 28.159  33.065  8.779   1.000 62.635  0 29  LYS   A C     1 ? 
ATOM   235  O  O     . LYS   A 1 29  ? 28.616  33.042  9.910   1.000 53.600  0 29  LYS   A O     1 ? 
ATOM   236  C  CB    . LYS   A 1 29  ? 29.774  32.361  7.019   1.000 69.681  0 29  LYS   A CB    1 ? 
ATOM   237  C  CG    . LYS   A 1 29  ? 30.627  31.217  6.517   1.000 79.471  0 29  LYS   A CG    1 ? 
ATOM   238  C  CD    . LYS   A 1 29  ? 31.690  31.626  5.506   1.000 88.510  0 29  LYS   A CD    1 ? 
ATOM   239  C  CE    . LYS   A 1 29  ? 32.215  30.442  4.741   1.000 91.858  0 29  LYS   A CE    1 ? 
ATOM   240  N  NZ    . LYS   A 1 29  ? 32.383  30.780  3.327   1.000 85.927  0 29  LYS   A NZ    1 ? 
ATOM   241  N  N     . GLU   A 1 30  ? 27.343  34.035  8.342   1.000 63.674  0 30  GLU   A N     1 ? 
ATOM   242  C  CA    . GLU   A 1 30  ? 26.985  35.211  9.128   1.000 69.652  0 30  GLU   A CA    1 ? 
ATOM   243  C  C     . GLU   A 1 30  ? 25.718  34.965  9.955   1.000 61.238  0 30  GLU   A C     1 ? 
ATOM   244  O  O     . GLU   A 1 30  ? 25.327  35.824  10.733  1.000 63.786  0 30  GLU   A O     1 ? 
ATOM   245  C  CB    . GLU   A 1 30  ? 26.834  36.438  8.205   1.000 74.558  0 30  GLU   A CB    1 ? 
ATOM   246  C  CG    . GLU   A 1 30  ? 27.994  37.442  8.182   1.000 91.578  0 30  GLU   A CG    1 ? 
ATOM   247  C  CD    . GLU   A 1 30  ? 29.398  36.968  7.819   1.000 108.952 0 30  GLU   A CD    1 ? 
ATOM   248  O  OE1   . GLU   A 1 30  ? 29.665  36.668  6.630   1.000 116.514 0 30  GLU   A OE1   1 ? 
ATOM   249  O  OE2   . GLU   A 1 30  ? 30.243  36.906  8.743   1.000 107.277 0 30  GLU   A OE2   1 ? 
ATOM   250  N  N     . ASN   A 1 31  ? 25.023  33.834  9.781   1.000 55.758  0 31  ASN   A N     1 ? 
ATOM   251  C  CA    . ASN   A 1 31  ? 23.747  33.656  10.458  1.000 52.418  0 31  ASN   A CA    1 ? 
ATOM   252  C  C     . ASN   A 1 31  ? 23.992  33.050  11.837  1.000 53.302  0 31  ASN   A C     1 ? 
ATOM   253  O  O     . ASN   A 1 31  ? 24.486  31.947  11.940  1.000 53.845  0 31  ASN   A O     1 ? 
ATOM   254  C  CB    . ASN   A 1 31  ? 22.788  32.788  9.657   1.000 50.497  0 31  ASN   A CB    1 ? 
ATOM   255  C  CG    . ASN   A 1 31  ? 21.391  32.771  10.229  1.000 52.035  0 31  ASN   A CG    1 ? 
ATOM   256  O  OD1   . ASN   A 1 31  ? 21.200  32.516  11.422  1.000 55.198  0 31  ASN   A OD1   1 ? 
ATOM   257  N  ND2   . ASN   A 1 31  ? 20.387  32.999  9.392   1.000 51.044  0 31  ASN   A ND2   1 ? 
ATOM   258  N  N     . PRO   A 1 32  ? 23.630  33.730  12.942  1.000 56.945  0 32  PRO   A N     1 ? 
ATOM   259  C  CA    . PRO   A 1 32  ? 23.937  33.220  14.269  1.000 56.296  0 32  PRO   A CA    1 ? 
ATOM   260  C  C     . PRO   A 1 32  ? 23.033  32.107  14.785  1.000 51.238  0 32  PRO   A C     1 ? 
ATOM   261  O  O     . PRO   A 1 32  ? 23.298  31.597  15.862  1.000 50.742  0 32  PRO   A O     1 ? 
ATOM   262  C  CB    . PRO   A 1 32  ? 23.828  34.495  15.147  1.000 61.170  0 32  PRO   A CB    1 ? 
ATOM   263  C  CG    . PRO   A 1 32  ? 22.763  35.349  14.447  1.000 60.221  0 32  PRO   A CG    1 ? 
ATOM   264  C  CD    . PRO   A 1 32  ? 22.972  35.055  12.970  1.000 60.336  0 32  PRO   A CD    1 ? 
ATOM   265  N  N     . THR   A 1 33  ? 21.995  31.697  14.044  1.000 51.923  0 33  THR   A N     1 ? 
ATOM   266  C  CA    . THR   A 1 33  ? 21.217  30.517  14.441  1.000 47.437  0 33  THR   A CA    1 ? 
ATOM   267  C  C     . THR   A 1 33  ? 21.657  29.252  13.681  1.000 50.364  0 33  THR   A C     1 ? 
ATOM   268  O  O     . THR   A 1 33  ? 21.043  28.202  13.840  1.000 51.734  0 33  THR   A O     1 ? 
ATOM   269  C  CB    . THR   A 1 33  ? 19.717  30.771  14.269  1.000 53.159  0 33  THR   A CB    1 ? 
ATOM   270  O  OG1   . THR   A 1 33  ? 19.407  30.943  12.890  1.000 47.295  0 33  THR   A OG1   1 ? 
ATOM   271  C  CG2   . THR   A 1 33  ? 19.260  31.966  15.092  1.000 57.211  0 33  THR   A CG2   1 ? 
ATOM   272  N  N     . ILE   A 1 34  ? 22.742  29.339  12.903  1.000 47.776  0 34  ILE   A N     1 ? 
ATOM   273  C  CA    . ILE   A 1 34  ? 23.236  28.236  12.098  1.000 50.605  0 34  ILE   A CA    1 ? 
ATOM   274  C  C     . ILE   A 1 34  ? 24.610  27.800  12.602  1.000 50.660  0 34  ILE   A C     1 ? 
ATOM   275  O  O     . ILE   A 1 34  ? 25.494  28.627  12.819  1.000 51.286  0 34  ILE   A O     1 ? 
ATOM   276  C  CB    . ILE   A 1 34  ? 23.314  28.654  10.624  1.000 49.717  0 34  ILE   A CB    1 ? 
ATOM   277  C  CG1   . ILE   A 1 34  ? 21.941  28.733  9.965   1.000 58.065  0 34  ILE   A CG1   1 ? 
ATOM   278  C  CG2   . ILE   A 1 34  ? 24.247  27.734  9.854   1.000 56.147  0 34  ILE   A CG2   1 ? 
ATOM   279  C  CD1   . ILE   A 1 34  ? 21.136  27.446  9.978   1.000 64.812  0 34  ILE   A CD1   1 ? 
ATOM   280  N  N     . ASP   A 1 35  ? 24.765  26.489  12.800  1.000 48.973  0 35  ASP   A N     1 ? 
ATOM   281  C  CA    . ASP   A 1 35  ? 26.061  25.865  12.997  1.000 50.778  0 35  ASP   A CA    1 ? 
ATOM   282  C  C     . ASP   A 1 35  ? 26.510  25.284  11.659  1.000 50.390  0 35  ASP   A C     1 ? 
ATOM   283  O  O     . ASP   A 1 35  ? 26.165  24.142  11.316  1.000 55.207  0 35  ASP   A O     1 ? 
ATOM   284  C  CB    . ASP   A 1 35  ? 25.995  24.801  14.087  1.000 52.834  0 35  ASP   A CB    1 ? 
ATOM   285  C  CG    . ASP   A 1 35  ? 27.260  23.959  14.268  1.000 56.993  0 35  ASP   A CG    1 ? 
ATOM   286  O  OD1   . ASP   A 1 35  ? 28.201  24.102  13.452  1.000 58.900  0 35  ASP   A OD1   1 ? 
ATOM   287  O  OD2   . ASP   A 1 35  ? 27.309  23.175  15.232  1.000 57.037  0 35  ASP   A OD2   1 ? 
ATOM   288  N  N     . LEU   A 1 36  ? 27.268  26.086  10.917  1.000 50.958  0 36  LEU   A N     1 ? 
ATOM   289  C  CA    . LEU   A 1 36  ? 27.701  25.715  9.580   1.000 52.410  0 36  LEU   A CA    1 ? 
ATOM   290  C  C     . LEU   A 1 36  ? 28.797  24.662  9.618   1.000 49.573  0 36  LEU   A C     1 ? 
ATOM   291  O  O     . LEU   A 1 36  ? 28.912  23.838  8.716   1.000 49.879  0 36  LEU   A O     1 ? 
ATOM   292  C  CB    . LEU   A 1 36  ? 28.187  26.930  8.801   1.000 54.851  0 36  LEU   A CB    1 ? 
ATOM   293  C  CG    . LEU   A 1 36  ? 28.533  26.656  7.330   1.000 58.437  0 36  LEU   A CG    1 ? 
ATOM   294  C  CD1   . LEU   A 1 36  ? 27.331  26.069  6.598   1.000 50.320  0 36  LEU   A CD1   1 ? 
ATOM   295  C  CD2   . LEU   A 1 36  ? 29.015  27.941  6.663   1.000 59.256  0 36  LEU   A CD2   1 ? 
ATOM   296  N  N     . GLU   A 1 37  ? 29.619  24.696  10.653  1.000 52.662  0 37  GLU   A N     1 ? 
ATOM   297  C  CA    . GLU   A 1 37  ? 30.708  23.744  10.754  1.000 52.459  0 37  GLU   A CA    1 ? 
ATOM   298  C  C     . GLU   A 1 37  ? 30.170  22.308  10.827  1.000 53.932  0 37  GLU   A C     1 ? 
ATOM   299  O  O     . GLU   A 1 37  ? 30.822  21.413  10.318  1.000 45.569  0 37  GLU   A O     1 ? 
ATOM   300  C  CB    . GLU   A 1 37  ? 31.550  24.076  11.978  1.000 61.951  0 37  GLU   A CB    1 ? 
ATOM   301  C  CG    . GLU   A 1 37  ? 32.778  23.185  12.157  1.000 87.030  0 37  GLU   A CG    1 ? 
ATOM   302  C  CD    . GLU   A 1 37  ? 33.363  23.382  13.547  1.000 104.130 0 37  GLU   A CD    1 ? 
ATOM   303  O  OE1   . GLU   A 1 37  ? 33.666  24.562  13.865  1.000 106.325 0 37  GLU   A OE1   1 ? 
ATOM   304  O  OE2   . GLU   A 1 37  ? 33.488  22.392  14.317  1.000 104.144 0 37  GLU   A OE2   1 ? 
ATOM   305  N  N     . ASN   A 1 38  ? 29.024  22.073  11.493  1.000 46.402  0 38  ASN   A N     1 ? 
ATOM   306  C  CA    . ASN   A 1 38  ? 28.508  20.717  11.674  1.000 52.470  0 38  ASN   A CA    1 ? 
ATOM   307  C  C     . ASN   A 1 38  ? 27.419  20.384  10.641  1.000 49.319  0 38  ASN   A C     1 ? 
ATOM   308  O  O     . ASN   A 1 38  ? 26.740  19.365  10.752  1.000 53.823  0 38  ASN   A O     1 ? 
ATOM   309  C  CB    . ASN   A 1 38  ? 28.100  20.473  13.121  1.000 47.728  0 38  ASN   A CB    1 ? 
ATOM   310  C  CG    . ASN   A 1 38  ? 29.293  20.536  14.055  1.000 50.228  0 38  ASN   A CG    1 ? 
ATOM   311  O  OD1   . ASN   A 1 38  ? 29.250  21.261  15.050  1.000 52.681  0 38  ASN   A OD1   1 ? 
ATOM   312  N  ND2   . ASN   A 1 38  ? 30.346  19.767  13.805  1.000 44.422  0 38  ASN   A ND2   1 ? 
ATOM   313  N  N     . SER   A 1 39  ? 27.281  21.252  9.624   1.000 47.312  0 39  SER   A N     1 ? 
ATOM   314  C  CA    . SER   A 1 39  ? 26.308  21.082  8.569   1.000 45.316  0 39  SER   A CA    1 ? 
ATOM   315  C  C     . SER   A 1 39  ? 26.896  20.230  7.455   1.000 45.548  0 39  SER   A C     1 ? 
ATOM   316  O  O     . SER   A 1 39  ? 28.105  20.091  7.352   1.000 51.213  0 39  SER   A O     1 ? 
ATOM   317  C  CB    . SER   A 1 39  ? 25.853  22.417  8.038   1.000 47.969  0 39  SER   A CB    1 ? 
ATOM   318  O  OG    . SER   A 1 39  ? 25.144  23.130  9.030   1.000 47.860  0 39  SER   A OG    1 ? 
ATOM   319  N  N     . TYR   A 1 40  ? 26.028  19.717  6.575   1.000 50.808  0 40  TYR   A N     1 ? 
ATOM   320  C  CA    . TYR   A 1 40  ? 26.451  18.823  5.511   1.000 43.648  0 40  TYR   A CA    1 ? 
ATOM   321  C  C     . TYR   A 1 40  ? 26.422  19.584  4.192   1.000 49.202  0 40  TYR   A C     1 ? 
ATOM   322  O  O     . TYR   A 1 40  ? 25.372  20.049  3.757   1.000 46.884  0 40  TYR   A O     1 ? 
ATOM   323  C  CB    . TYR   A 1 40  ? 25.575  17.569  5.452   1.000 42.878  0 40  TYR   A CB    1 ? 
ATOM   324  C  CG    . TYR   A 1 40  ? 25.980  16.528  4.416   1.000 51.805  0 40  TYR   A CG    1 ? 
ATOM   325  C  CD1   . TYR   A 1 40  ? 25.562  16.632  3.090   1.000 43.181  0 40  TYR   A CD1   1 ? 
ATOM   326  C  CD2   . TYR   A 1 40  ? 26.717  15.401  4.780   1.000 47.058  0 40  TYR   A CD2   1 ? 
ATOM   327  C  CE1   . TYR   A 1 40  ? 25.881  15.662  2.155   1.000 55.280  0 40  TYR   A CE1   1 ? 
ATOM   328  C  CE2   . TYR   A 1 40  ? 27.028  14.418  3.849   1.000 52.829  0 40  TYR   A CE2   1 ? 
ATOM   329  C  CZ    . TYR   A 1 40  ? 26.580  14.530  2.541   1.000 53.750  0 40  TYR   A CZ    1 ? 
ATOM   330  O  OH    . TYR   A 1 40  ? 26.912  13.626  1.566   1.000 58.458  0 40  TYR   A OH    1 ? 
ATOM   331  N  N     . VAL   A 1 41  ? 27.597  19.644  3.560   1.000 48.778  0 41  VAL   A N     1 ? 
ATOM   332  C  CA    . VAL   A 1 41  ? 27.779  20.219  2.240   1.000 51.203  0 41  VAL   A CA    1 ? 
ATOM   333  C  C     . VAL   A 1 41  ? 28.066  19.088  1.258   1.000 46.120  0 41  VAL   A C     1 ? 
ATOM   334  O  O     . VAL   A 1 41  ? 29.116  18.476  1.288   1.000 45.520  0 41  VAL   A O     1 ? 
ATOM   335  C  CB    . VAL   A 1 41  ? 28.945  21.232  2.274   1.000 47.172  0 41  VAL   A CB    1 ? 
ATOM   336  C  CG1   . VAL   A 1 41  ? 29.176  21.867  0.917   1.000 56.595  0 41  VAL   A CG1   1 ? 
ATOM   337  C  CG2   . VAL   A 1 41  ? 28.715  22.321  3.315   1.000 50.935  0 41  VAL   A CG2   1 ? 
ATOM   338  N  N     . PRO   A 1 42  ? 27.146  18.752  0.352   1.000 43.885  0 42  PRO   A N     1 ? 
ATOM   339  C  CA    . PRO   A 1 42  ? 27.364  17.640  -0.581  1.000 48.480  0 42  PRO   A CA    1 ? 
ATOM   340  C  C     . PRO   A 1 42  ? 28.710  17.659  -1.295  1.000 51.373  0 42  PRO   A C     1 ? 
ATOM   341  O  O     . PRO   A 1 42  ? 29.418  16.640  -1.332  1.000 51.197  0 42  PRO   A O     1 ? 
ATOM   342  C  CB    . PRO   A 1 42  ? 26.200  17.800  -1.557  1.000 47.825  0 42  PRO   A CB    1 ? 
ATOM   343  C  CG    . PRO   A 1 42  ? 25.121  18.383  -0.686  1.000 46.946  0 42  PRO   A CG    1 ? 
ATOM   344  C  CD    . PRO   A 1 42  ? 25.839  19.383  0.197   1.000 47.005  0 42  PRO   A CD    1 ? 
ATOM   345  N  N     . LEU   A 1 43  ? 29.090  18.837  -1.791  1.000 50.840  0 43  LEU   A N     1 ? 
ATOM   346  C  CA    . LEU   A 1 43  ? 30.273  18.941  -2.632  1.000 57.011  0 43  LEU   A CA    1 ? 
ATOM   347  C  C     . LEU   A 1 43  ? 31.531  18.525  -1.870  1.000 49.505  0 43  LEU   A C     1 ? 
ATOM   348  O  O     . LEU   A 1 43  ? 32.467  18.056  -2.485  1.000 57.565  0 43  LEU   A O     1 ? 
ATOM   349  C  CB    . LEU   A 1 43  ? 30.363  20.355  -3.203  1.000 56.168  0 43  LEU   A CB    1 ? 
ATOM   350  C  CG    . LEU   A 1 43  ? 30.833  20.507  -4.654  1.000 67.792  0 43  LEU   A CG    1 ? 
ATOM   351  C  CD1   . LEU   A 1 43  ? 30.353  19.430  -5.603  1.000 62.354  0 43  LEU   A CD1   1 ? 
ATOM   352  C  CD2   . LEU   A 1 43  ? 30.378  21.854  -5.192  1.000 70.525  0 43  LEU   A CD2   1 ? 
ATOM   353  N  N     . ASP   A 1 44  ? 31.524  18.615  -0.536  1.000 52.353  0 44  ASP   A N     1 ? 
ATOM   354  C  CA    . ASP   A 1 44  ? 32.655  18.193  0.289   1.000 51.960  0 44  ASP   A CA    1 ? 
ATOM   355  C  C     . ASP   A 1 44  ? 32.439  16.802  0.888   1.000 45.147  0 44  ASP   A C     1 ? 
ATOM   356  O  O     . ASP   A 1 44  ? 33.201  16.382  1.738   1.000 54.245  0 44  ASP   A O     1 ? 
ATOM   357  C  CB    . ASP   A 1 44  ? 32.863  19.087  1.514   1.000 63.270  0 44  ASP   A CB    1 ? 
ATOM   358  C  CG    . ASP   A 1 44  ? 32.924  20.589  1.283   1.000 60.302  0 44  ASP   A CG    1 ? 
ATOM   359  O  OD1   . ASP   A 1 44  ? 33.292  20.998  0.140   1.000 67.489  0 44  ASP   A OD1   1 ? 
ATOM   360  O  OD2   . ASP   A 1 44  ? 32.560  21.325  2.236   1.000 73.207  0 44  ASP   A OD2   1 ? 
ATOM   361  N  N     . ASN   A 1 45  ? 31.408  16.072  0.476   1.000 46.412  0 45  ASN   A N     1 ? 
ATOM   362  C  CA    . ASN   A 1 45  ? 31.128  14.775  1.076   1.000 52.621  0 45  ASN   A CA    1 ? 
ATOM   363  C  C     . ASN   A 1 45  ? 30.992  13.703  -0.003  1.000 51.078  0 45  ASN   A C     1 ? 
ATOM   364  O  O     . ASN   A 1 45  ? 30.360  12.682  0.244   1.000 55.267  0 45  ASN   A O     1 ? 
ATOM   365  C  CB    . ASN   A 1 45  ? 29.878  14.882  1.952   1.000 55.783  0 45  ASN   A CB    1 ? 
ATOM   366  C  CG    . ASN   A 1 45  ? 30.191  15.591  3.245   1.000 61.020  0 45  ASN   A CG    1 ? 
ATOM   367  O  OD1   . ASN   A 1 45  ? 30.034  16.820  3.350   1.000 64.580  0 45  ASN   A OD1   1 ? 
ATOM   368  N  ND2   . ASN   A 1 45  ? 30.658  14.828  4.222   1.000 63.072  0 45  ASN   A ND2   1 ? 
ATOM   369  N  N     . GLN   A 1 46  ? 31.545  13.948  -1.201  1.000 57.520  0 46  GLN   A N     1 ? 
ATOM   370  C  CA    . GLN   A 1 46  ? 31.386  12.994  -2.289  1.000 50.793  0 46  GLN   A CA    1 ? 
ATOM   371  C  C     . GLN   A 1 46  ? 32.287  11.827  -1.915  1.000 47.963  0 46  GLN   A C     1 ? 
ATOM   372  O  O     . GLN   A 1 46  ? 33.267  12.001  -1.180  1.000 44.122  0 46  GLN   A O     1 ? 
ATOM   373  C  CB    . GLN   A 1 46  ? 31.617  13.547  -3.703  1.000 55.461  0 46  GLN   A CB    1 ? 
ATOM   374  C  CG    . GLN   A 1 46  ? 30.794  14.767  -4.137  1.000 57.859  0 46  GLN   A CG    1 ? 
ATOM   375  C  CD    . GLN   A 1 46  ? 29.288  14.562  -4.289  1.000 80.302  0 46  GLN   A CD    1 ? 
ATOM   376  O  OE1   . GLN   A 1 46  ? 28.737  14.395  -5.400  1.000 67.079  0 46  GLN   A OE1   1 ? 
ATOM   377  N  NE2   . GLN   A 1 46  ? 28.580  14.625  -3.161  1.000 89.229  0 46  GLN   A NE2   1 ? 
ATOM   378  N  N     . TYR   A 1 47  ? 31.902  10.611  -2.304  1.000 49.770  0 47  TYR   A N     1 ? 
ATOM   379  C  CA    . TYR   A 1 47  ? 32.689  9.442   -1.930  1.000 55.004  0 47  TYR   A CA    1 ? 
ATOM   380  C  C     . TYR   A 1 47  ? 34.137  9.610   -2.392  1.000 51.756  0 47  TYR   A C     1 ? 
ATOM   381  O  O     . TYR   A 1 47  ? 34.375  9.930   -3.569  1.000 53.398  0 47  TYR   A O     1 ? 
ATOM   382  C  CB    . TYR   A 1 47  ? 32.149  8.147   -2.551  1.000 51.735  0 47  TYR   A CB    1 ? 
ATOM   383  C  CG    . TYR   A 1 47  ? 32.760  6.854   -2.001  1.000 57.556  0 47  TYR   A CG    1 ? 
ATOM   384  C  CD1   . TYR   A 1 47  ? 32.840  6.611   -0.630  1.000 60.270  0 47  TYR   A CD1   1 ? 
ATOM   385  C  CD2   . TYR   A 1 47  ? 33.212  5.852   -2.861  1.000 61.990  0 47  TYR   A CD2   1 ? 
ATOM   386  C  CE1   . TYR   A 1 47  ? 33.359  5.420   -0.134  1.000 59.642  0 47  TYR   A CE1   1 ? 
ATOM   387  C  CE2   . TYR   A 1 47  ? 33.740  4.662   -2.379  1.000 64.950  0 47  TYR   A CE2   1 ? 
ATOM   388  C  CZ    . TYR   A 1 47  ? 33.820  4.452   -1.011  1.000 68.258  0 47  TYR   A CZ    1 ? 
ATOM   389  O  OH    . TYR   A 1 47  ? 34.352  3.289   -0.525  1.000 69.379  0 47  TYR   A OH    1 ? 
ATOM   390  N  N     . LYS   A 1 48  ? 35.064  9.432   -1.445  1.000 58.742  0 48  LYS   A N     1 ? 
ATOM   391  C  CA    . LYS   A 1 48  ? 36.510  9.457   -1.670  1.000 68.364  0 48  LYS   A CA    1 ? 
ATOM   392  C  C     . LYS   A 1 48  ? 37.052  10.833  -2.089  1.000 82.209  0 48  LYS   A C     1 ? 
ATOM   393  O  O     . LYS   A 1 48  ? 38.212  10.914  -2.472  1.000 89.022  0 48  LYS   A O     1 ? 
ATOM   394  C  CB    . LYS   A 1 48  ? 36.919  8.370   -2.690  1.000 65.686  0 48  LYS   A CB    1 ? 
ATOM   395  C  CG    . LYS   A 1 48  ? 37.347  6.998   -2.140  1.000 55.257  0 48  LYS   A CG    1 ? 
ATOM   396  C  CD    . LYS   A 1 48  ? 37.150  5.892   -3.165  1.000 56.370  0 48  LYS   A CD    1 ? 
ATOM   397  C  CE    . LYS   A 1 48  ? 37.559  4.577   -2.595  1.000 63.106  0 48  LYS   A CE    1 ? 
ATOM   398  N  NZ    . LYS   A 1 48  ? 37.673  3.610   -3.677  1.000 62.619  0 48  LYS   A NZ    1 ? 
ATOM   399  N  N     . GLY   A 1 49  ? 36.275  11.927  -1.993  1.000 83.434  0 49  GLY   A N     1 ? 
ATOM   400  C  CA    . GLY   A 1 49  ? 36.742  13.249  -2.417  1.000 61.165  0 49  GLY   A CA    1 ? 
ATOM   401  C  C     . GLY   A 1 49  ? 36.480  13.517  -3.908  1.000 81.258  0 49  GLY   A C     1 ? 
ATOM   402  O  O     . GLY   A 1 49  ? 36.610  14.644  -4.396  1.000 76.219  0 49  GLY   A O     1 ? 
ATOM   403  N  N     . ILE   A 1 50  ? 36.037  12.504  -4.656  1.000 88.066  0 50  ILE   A N     1 ? 
ATOM   404  C  CA    . ILE   A 1 50  ? 36.032  12.625  -6.104  1.000 94.398  0 50  ILE   A CA    1 ? 
ATOM   405  C  C     . ILE   A 1 50  ? 34.761  13.344  -6.573  1.000 100.638 0 50  ILE   A C     1 ? 
ATOM   406  O  O     . ILE   A 1 50  ? 33.677  13.142  -6.028  1.000 104.971 0 50  ILE   A O     1 ? 
ATOM   407  C  CB    . ILE   A 1 50  ? 36.254  11.255  -6.787  1.000 107.270 0 50  ILE   A CB    1 ? 
ATOM   408  C  CG1   . ILE   A 1 50  ? 34.967  10.484  -7.029  1.000 118.081 0 50  ILE   A CG1   1 ? 
ATOM   409  C  CG2   . ILE   A 1 50  ? 37.291  10.414  -6.037  1.000 102.290 0 50  ILE   A CG2   1 ? 
ATOM   410  C  CD1   . ILE   A 1 50  ? 34.213  10.879  -8.294  1.000 129.133 0 50  ILE   A CD1   1 ? 
ATOM   411  N  N     . ARG   A 1 51  ? 34.909  14.182  -7.613  1.000 87.810  0 51  ARG   A N     1 ? 
ATOM   412  C  CA    . ARG   A 1 51  ? 33.785  14.832  -8.255  1.000 74.563  0 51  ARG   A CA    1 ? 
ATOM   413  C  C     . ARG   A 1 51  ? 33.738  14.385  -9.712  1.000 74.328  0 51  ARG   A C     1 ? 
ATOM   414  O  O     . ARG   A 1 51  ? 34.704  14.545  -10.448 1.000 72.964  0 51  ARG   A O     1 ? 
ATOM   415  C  CB    . ARG   A 1 51  ? 33.985  16.351  -8.135  1.000 105.464 0 51  ARG   A CB    1 ? 
ATOM   416  C  CG    . ARG   A 1 51  ? 34.807  16.768  -6.920  1.000 109.633 0 51  ARG   A CG    1 ? 
ATOM   417  C  CD    . ARG   A 1 51  ? 34.837  18.284  -6.776  1.000 116.826 0 51  ARG   A CD    1 ? 
ATOM   418  N  NE    . ARG   A 1 51  ? 35.221  18.737  -5.433  1.000 103.651 0 51  ARG   A NE    1 ? 
ATOM   419  C  CZ    . ARG   A 1 51  ? 34.994  19.968  -4.962  1.000 109.570 0 51  ARG   A CZ    1 ? 
ATOM   420  N  NH1   . ARG   A 1 51  ? 34.485  20.909  -5.746  1.000 98.835  0 51  ARG   A NH1   1 ? 
ATOM   421  N  NH2   . ARG   A 1 51  ? 35.267  20.253  -3.699  1.000 105.782 0 51  ARG   A NH2   1 ? 
ATOM   422  N  N     . VAL   A 1 52  ? 32.616  13.830  -10.158 1.000 88.076  0 52  VAL   A N     1 ? 
ATOM   423  C  CA    . VAL   A 1 52  ? 32.516  13.341  -11.532 1.000 111.360 0 52  VAL   A CA    1 ? 
ATOM   424  C  C     . VAL   A 1 52  ? 32.937  14.404  -12.573 1.000 104.224 0 52  VAL   A C     1 ? 
ATOM   425  O  O     . VAL   A 1 52  ? 33.101  14.093  -13.762 1.000 76.810  0 52  VAL   A O     1 ? 
ATOM   426  C  CB    . VAL   A 1 52  ? 31.087  12.809  -11.783 1.000 117.076 0 52  VAL   A CB    1 ? 
ATOM   427  C  CG1   . VAL   A 1 52  ? 30.152  13.886  -12.343 1.000 129.361 0 52  VAL   A CG1   1 ? 
ATOM   428  C  CG2   . VAL   A 1 52  ? 31.086  11.575  -12.687 1.000 100.796 0 52  VAL   A CG2   1 ? 
ATOM   429  N  N     . ASP   A 1 53  ? 33.075  15.677  -12.161 1.000 98.636  0 53  ASP   A N     1 ? 
ATOM   430  C  CA    . ASP   A 1 53  ? 33.560  16.722  -13.061 1.000 95.008  0 53  ASP   A CA    1 ? 
ATOM   431  C  C     . ASP   A 1 53  ? 35.094  16.698  -13.096 1.000 74.491  0 53  ASP   A C     1 ? 
ATOM   432  O  O     . ASP   A 1 53  ? 35.667  16.854  -14.159 1.000 71.101  0 53  ASP   A O     1 ? 
ATOM   433  C  CB    . ASP   A 1 53  ? 32.942  18.095  -12.772 1.000 82.052  0 53  ASP   A CB    1 ? 
ATOM   434  C  CG    . ASP   A 1 53  ? 32.932  18.581  -11.329 1.000 80.270  0 53  ASP   A CG    1 ? 
ATOM   435  O  OD1   . ASP   A 1 53  ? 34.003  18.946  -10.792 1.000 84.702  0 53  ASP   A OD1   1 ? 
ATOM   436  O  OD2   . ASP   A 1 53  ? 31.839  18.622  -10.744 1.000 110.712 0 53  ASP   A OD2   1 ? 
ATOM   437  N  N     . GLU   A 1 54  ? 35.734  16.525  -11.931 1.000 68.212  0 54  GLU   A N     1 ? 
ATOM   438  C  CA    . GLU   A 1 54  ? 37.183  16.553  -11.790 1.000 67.277  0 54  GLU   A CA    1 ? 
ATOM   439  C  C     . GLU   A 1 54  ? 37.821  15.189  -12.076 1.000 80.821  0 54  GLU   A C     1 ? 
ATOM   440  O  O     . GLU   A 1 54  ? 39.013  15.144  -12.379 1.000 82.707  0 54  GLU   A O     1 ? 
ATOM   441  C  CB    . GLU   A 1 54  ? 37.605  17.056  -10.410 1.000 72.517  0 54  GLU   A CB    1 ? 
ATOM   442  C  CG    . GLU   A 1 54  ? 37.322  18.544  -10.190 1.000 83.438  0 54  GLU   A CG    1 ? 
ATOM   443  C  CD    . GLU   A 1 54  ? 37.962  19.177  -8.966  1.000 93.574  0 54  GLU   A CD    1 ? 
ATOM   444  O  OE1   . GLU   A 1 54  ? 38.555  18.460  -8.135  1.000 92.699  0 54  GLU   A OE1   1 ? 
ATOM   445  O  OE2   . GLU   A 1 54  ? 37.882  20.416  -8.852  1.000 100.096 0 54  GLU   A OE2   1 ? 
ATOM   446  N  N     . HIS   A 1 55  ? 37.052  14.089  -11.977 1.000 78.747  0 55  HIS   A N     1 ? 
ATOM   447  C  CA    . HIS   A 1 55  ? 37.551  12.733  -12.219 1.000 62.561  0 55  HIS   A CA    1 ? 
ATOM   448  C  C     . HIS   A 1 55  ? 36.460  11.897  -12.877 1.000 57.494  0 55  HIS   A C     1 ? 
ATOM   449  O  O     . HIS   A 1 55  ? 35.875  11.046  -12.220 1.000 73.009  0 55  HIS   A O     1 ? 
ATOM   450  C  CB    . HIS   A 1 55  ? 38.003  12.051  -10.927 1.000 60.954  0 55  HIS   A CB    1 ? 
ATOM   451  C  CG    . HIS   A 1 55  ? 39.084  12.743  -10.149 1.000 56.060  0 55  HIS   A CG    1 ? 
ATOM   452  N  ND1   . HIS   A 1 55  ? 40.427  12.604  -10.406 1.000 70.325  0 55  HIS   A ND1   1 ? 
ATOM   453  C  CD2   . HIS   A 1 55  ? 39.010  13.532  -9.067  1.000 61.758  0 55  HIS   A CD2   1 ? 
ATOM   454  C  CE1   . HIS   A 1 55  ? 41.119  13.336  -9.525  1.000 61.046  0 55  HIS   A CE1   1 ? 
ATOM   455  N  NE2   . HIS   A 1 55  ? 40.276  13.921  -8.703  1.000 54.765  0 55  HIS   A NE2   1 ? 
ATOM   456  N  N     . PRO   A 1 56  ? 36.181  12.109  -14.185 1.000 57.277  0 56  PRO   A N     1 ? 
ATOM   457  C  CA    . PRO   A 1 56  ? 35.097  11.461  -14.922 1.000 63.672  0 56  PRO   A CA    1 ? 
ATOM   458  C  C     . PRO   A 1 56  ? 35.129  9.950   -15.109 1.000 80.571  0 56  PRO   A C     1 ? 
ATOM   459  O  O     . PRO   A 1 56  ? 34.270  9.389   -15.820 1.000 72.214  0 56  PRO   A O     1 ? 
ATOM   460  C  CB    . PRO   A 1 56  ? 35.152  12.093  -16.339 1.000 63.210  0 56  PRO   A CB    1 ? 
ATOM   461  C  CG    . PRO   A 1 56  ? 36.038  13.305  -16.212 1.000 74.842  0 56  PRO   A CG    1 ? 
ATOM   462  C  CD    . PRO   A 1 56  ? 36.959  13.011  -15.043 1.000 69.845  0 56  PRO   A CD    1 ? 
ATOM   463  N  N     . GLU   A 1 57  ? 36.174  9.327   -14.550 1.000 70.291  0 57  GLU   A N     1 ? 
ATOM   464  C  CA    . GLU   A 1 57  ? 36.271  7.883   -14.554 1.000 73.025  0 57  GLU   A CA    1 ? 
ATOM   465  C  C     . GLU   A 1 57  ? 35.242  7.311   -13.580 1.000 65.290  0 57  GLU   A C     1 ? 
ATOM   466  O  O     . GLU   A 1 57  ? 34.842  6.179   -13.758 1.000 71.830  0 57  GLU   A O     1 ? 
ATOM   467  C  CB    . GLU   A 1 57  ? 37.703  7.395   -14.299 1.000 65.210  0 57  GLU   A CB    1 ? 
ATOM   468  C  CG    . GLU   A 1 57  ? 38.319  7.731   -12.943 1.000 59.245  0 57  GLU   A CG    1 ? 
ATOM   469  C  CD    . GLU   A 1 57  ? 39.123  9.025   -12.870 1.000 59.130  0 57  GLU   A CD    1 ? 
ATOM   470  O  OE1   . GLU   A 1 57  ? 38.905  9.914   -13.738 1.000 51.106  0 57  GLU   A OE1   1 ? 
ATOM   471  O  OE2   . GLU   A 1 57  ? 39.965  9.140   -11.948 1.000 55.149  0 57  GLU   A OE2   1 ? 
ATOM   472  N  N     . TYR   A 1 58  ? 34.777  8.099   -12.597 1.000 73.908  0 58  TYR   A N     1 ? 
ATOM   473  C  CA    . TYR   A 1 58  ? 33.823  7.600   -11.613 1.000 78.755  0 58  TYR   A CA    1 ? 
ATOM   474  C  C     . TYR   A 1 58  ? 32.362  7.782   -12.029 1.000 73.601  0 58  TYR   A C     1 ? 
ATOM   475  O  O     . TYR   A 1 58  ? 31.475  7.534   -11.229 1.000 89.639  0 58  TYR   A O     1 ? 
ATOM   476  C  CB    . TYR   A 1 58  ? 34.043  8.279   -10.275 1.000 68.699  0 58  TYR   A CB    1 ? 
ATOM   477  C  CG    . TYR   A 1 58  ? 35.337  7.936   -9.558  1.000 76.134  0 58  TYR   A CG    1 ? 
ATOM   478  C  CD1   . TYR   A 1 58  ? 36.494  8.674   -9.767  1.000 80.491  0 58  TYR   A CD1   1 ? 
ATOM   479  C  CD2   . TYR   A 1 58  ? 35.381  6.905   -8.629  1.000 81.306  0 58  TYR   A CD2   1 ? 
ATOM   480  C  CE1   . TYR   A 1 58  ? 37.660  8.394   -9.070  1.000 76.346  0 58  TYR   A CE1   1 ? 
ATOM   481  C  CE2   . TYR   A 1 58  ? 36.539  6.607   -7.931  1.000 76.308  0 58  TYR   A CE2   1 ? 
ATOM   482  C  CZ    . TYR   A 1 58  ? 37.687  7.348   -8.162  1.000 80.975  0 58  TYR   A CZ    1 ? 
ATOM   483  O  OH    . TYR   A 1 58  ? 38.835  7.076   -7.469  1.000 74.368  0 58  TYR   A OH    1 ? 
ATOM   484  N  N     . LEU   A 1 59  ? 32.118  8.079   -13.304 1.000 81.719  0 59  LEU   A N     1 ? 
ATOM   485  C  CA    . LEU   A 1 59  ? 30.805  8.389   -13.868 1.000 99.226  0 59  LEU   A CA    1 ? 
ATOM   486  C  C     . LEU   A 1 59  ? 30.027  7.109   -14.204 1.000 95.653  0 59  LEU   A C     1 ? 
ATOM   487  O  O     . LEU   A 1 59  ? 28.898  7.155   -14.736 1.000 66.515  0 59  LEU   A O     1 ? 
ATOM   488  C  CB    . LEU   A 1 59  ? 31.167  9.215   -15.118 1.000 112.557 0 59  LEU   A CB    1 ? 
ATOM   489  C  CG    . LEU   A 1 59  ? 30.078  9.740   -16.073 1.000 114.052 0 59  LEU   A CG    1 ? 
ATOM   490  C  CD1   . LEU   A 1 59  ? 29.258  10.911  -15.549 1.000 112.022 0 59  LEU   A CD1   1 ? 
ATOM   491  C  CD2   . LEU   A 1 59  ? 30.730  10.168  -17.384 1.000 101.957 0 59  LEU   A CD2   1 ? 
ATOM   492  N  N     . HIS   A 1 60  ? 30.706  5.970   -14.009 1.000 90.805  0 60  HIS   A N     1 ? 
ATOM   493  C  CA    . HIS   A 1 60  ? 30.140  4.659   -14.272 1.000 94.237  0 60  HIS   A CA    1 ? 
ATOM   494  C  C     . HIS   A 1 60  ? 30.445  3.731   -13.093 1.000 85.171  0 60  HIS   A C     1 ? 
ATOM   495  O  O     . HIS   A 1 60  ? 29.907  2.630   -13.098 1.000 84.206  0 60  HIS   A O     1 ? 
ATOM   496  C  CB    . HIS   A 1 60  ? 30.602  4.100   -15.636 1.000 106.085 0 60  HIS   A CB    1 ? 
ATOM   497  C  CG    . HIS   A 1 60  ? 29.880  4.611   -16.867 1.000 94.951  0 60  HIS   A CG    1 ? 
ATOM   498  N  ND1   . HIS   A 1 60  ? 30.381  5.624   -17.672 1.000 87.367  0 60  HIS   A ND1   1 ? 
ATOM   499  C  CD2   . HIS   A 1 60  ? 28.720  4.231   -17.456 1.000 82.331  0 60  HIS   A CD2   1 ? 
ATOM   500  C  CE1   . HIS   A 1 60  ? 29.551  5.848   -18.700 1.000 76.148  0 60  HIS   A CE1   1 ? 
ATOM   501  N  NE2   . HIS   A 1 60  ? 28.536  5.015   -18.590 1.000 70.418  0 60  HIS   A NE2   1 ? 
ATOM   502  N  N     . ASP   A 1 61  ? 31.269  4.164   -12.105 1.000 59.680  0 61  ASP   A N     1 ? 
ATOM   503  C  CA    . ASP   A 1 61  ? 31.469  3.440   -10.853 1.000 59.665  0 61  ASP   A CA    1 ? 
ATOM   504  C  C     . ASP   A 1 61  ? 30.191  3.487   -9.986  1.000 69.528  0 61  ASP   A C     1 ? 
ATOM   505  O  O     . ASP   A 1 61  ? 29.740  4.548   -9.552  1.000 75.168  0 61  ASP   A O     1 ? 
ATOM   506  C  CB    . ASP   A 1 61  ? 32.706  3.944   -10.118 1.000 55.909  0 61  ASP   A CB    1 ? 
ATOM   507  C  CG    . ASP   A 1 61  ? 33.045  3.248   -8.808  1.000 64.749  0 61  ASP   A CG    1 ? 
ATOM   508  O  OD1   . ASP   A 1 61  ? 32.294  2.336   -8.447  1.000 83.716  0 61  ASP   A OD1   1 ? 
ATOM   509  O  OD2   . ASP   A 1 61  ? 34.054  3.611   -8.145  1.000 64.452  0 61  ASP   A OD2   1 ? 
ATOM   510  N  N     . LYS   A 1 62  ? 29.594  2.311   -9.757  1.000 64.243  0 62  LYS   A N     1 ? 
ATOM   511  C  CA    . LYS   A 1 62  ? 28.339  2.173   -9.035  1.000 65.469  0 62  LYS   A CA    1 ? 
ATOM   512  C  C     . LYS   A 1 62  ? 28.588  2.230   -7.529  1.000 53.907  0 62  LYS   A C     1 ? 
ATOM   513  O  O     . LYS   A 1 62  ? 27.688  2.523   -6.766  1.000 51.874  0 62  LYS   A O     1 ? 
ATOM   514  C  CB    . LYS   A 1 62  ? 27.650  0.847   -9.377  1.000 60.601  0 62  LYS   A CB    1 ? 
ATOM   515  C  CG    . LYS   A 1 62  ? 27.094  0.778   -10.799 1.000 60.428  0 62  LYS   A CG    1 ? 
ATOM   516  C  CD    . LYS   A 1 62  ? 26.581  -0.623  -11.101 1.000 60.003  0 62  LYS   A CD    1 ? 
ATOM   517  C  CE    . LYS   A 1 62  ? 25.732  -0.768  -12.316 1.000 67.814  0 62  LYS   A CE    1 ? 
ATOM   518  N  NZ    . LYS   A 1 62  ? 26.491  -0.692  -13.566 1.000 69.552  0 62  LYS   A NZ    1 ? 
ATOM   519  N  N     . VAL   A 1 63  ? 29.807  1.928   -7.099  1.000 45.620  0 63  VAL   A N     1 ? 
ATOM   520  C  CA    . VAL   A 1 63  ? 30.181  2.046   -5.703  1.000 46.440  0 63  VAL   A CA    1 ? 
ATOM   521  C  C     . VAL   A 1 63  ? 30.239  3.526   -5.324  1.000 56.560  0 63  VAL   A C     1 ? 
ATOM   522  O  O     . VAL   A 1 63  ? 29.656  3.939   -4.324  1.000 64.911  0 63  VAL   A O     1 ? 
ATOM   523  C  CB    . VAL   A 1 63  ? 31.527  1.330   -5.476  1.000 49.543  0 63  VAL   A CB    1 ? 
ATOM   524  C  CG1   . VAL   A 1 63  ? 32.107  1.533   -4.075  1.000 50.617  0 63  VAL   A CG1   1 ? 
ATOM   525  C  CG2   . VAL   A 1 63  ? 31.434  -0.165  -5.786  1.000 57.914  0 63  VAL   A CG2   1 ? 
ATOM   526  N  N     . TRP   A 1 64  ? 30.955  4.324   -6.124  1.000 59.478  0 64  TRP   A N     1 ? 
ATOM   527  C  CA    . TRP   A 1 64  ? 31.013  5.755   -5.892  1.000 60.704  0 64  TRP   A CA    1 ? 
ATOM   528  C  C     . TRP   A 1 64  ? 29.597  6.325   -5.811  1.000 56.500  0 64  TRP   A C     1 ? 
ATOM   529  O  O     . TRP   A 1 64  ? 29.320  7.075   -4.890  1.000 52.342  0 64  TRP   A O     1 ? 
ATOM   530  C  CB    . TRP   A 1 64  ? 31.847  6.489   -6.960  1.000 61.072  0 64  TRP   A CB    1 ? 
ATOM   531  C  CG    . TRP   A 1 64  ? 31.790  7.982   -6.782  1.000 52.414  0 64  TRP   A CG    1 ? 
ATOM   532  C  CD1   . TRP   A 1 64  ? 32.552  8.749   -5.947  1.000 49.762  0 64  TRP   A CD1   1 ? 
ATOM   533  C  CD2   . TRP   A 1 64  ? 30.821  8.865   -7.381  1.000 42.587  0 64  TRP   A CD2   1 ? 
ATOM   534  N  NE1   . TRP   A 1 64  ? 32.144  10.060  -6.018  1.000 53.371  0 64  TRP   A NE1   1 ? 
ATOM   535  C  CE2   . TRP   A 1 64  ? 31.082  10.157  -6.881  1.000 47.991  0 64  TRP   A CE2   1 ? 
ATOM   536  C  CE3   . TRP   A 1 64  ? 29.768  8.689   -8.280  1.000 53.885  0 64  TRP   A CE3   1 ? 
ATOM   537  C  CZ2   . TRP   A 1 64  ? 30.328  11.259  -7.267  1.000 52.006  0 64  TRP   A CZ2   1 ? 
ATOM   538  C  CZ3   . TRP   A 1 64  ? 29.003  9.774   -8.647  1.000 56.741  0 64  TRP   A CZ3   1 ? 
ATOM   539  C  CH2   . TRP   A 1 64  ? 29.295  11.047  -8.159  1.000 54.599  0 64  TRP   A CH2   1 ? 
ATOM   540  N  N     . ALA   A 1 65  ? 28.729  5.957   -6.763  1.000 46.784  0 65  ALA   A N     1 ? 
ATOM   541  C  CA    . ALA   A 1 65  ? 27.375  6.465   -6.839  1.000 52.699  0 65  ALA   A CA    1 ? 
ATOM   542  C  C     . ALA   A 1 65  ? 26.556  6.041   -5.620  1.000 51.477  0 65  ALA   A C     1 ? 
ATOM   543  O  O     . ALA   A 1 65  ? 25.835  6.858   -5.056  1.000 52.871  0 65  ALA   A O     1 ? 
ATOM   544  C  CB    . ALA   A 1 65  ? 26.707  6.000   -8.127  1.000 50.443  0 65  ALA   A CB    1 ? 
ATOM   545  N  N     . THR   A 1 66  ? 26.649  4.760   -5.239  1.000 48.038  0 66  THR   A N     1 ? 
ATOM   546  C  CA    . THR   A 1 66  ? 25.914  4.235   -4.100  1.000 47.965  0 66  THR   A CA    1 ? 
ATOM   547  C  C     . THR   A 1 66  ? 26.285  5.024   -2.851  1.000 44.346  0 66  THR   A C     1 ? 
ATOM   548  O  O     . THR   A 1 66  ? 25.410  5.505   -2.148  1.000 47.875  0 66  THR   A O     1 ? 
ATOM   549  C  CB    . THR   A 1 66  ? 26.179  2.745   -3.893  1.000 50.026  0 66  THR   A CB    1 ? 
ATOM   550  O  OG1   . THR   A 1 66  ? 25.630  2.061   -5.006  1.000 44.330  0 66  THR   A OG1   1 ? 
ATOM   551  C  CG2   . THR   A 1 66  ? 25.425  2.195   -2.697  1.000 52.799  0 66  THR   A CG2   1 ? 
ATOM   552  N  N     . ALA   A 1 67  ? 27.591  5.160   -2.606  1.000 46.546  0 67  ALA   A N     1 ? 
ATOM   553  C  CA    . ALA   A 1 67  ? 28.087  5.796   -1.397  1.000 47.475  0 67  ALA   A CA    1 ? 
ATOM   554  C  C     . ALA   A 1 67  ? 27.755  7.278   -1.377  1.000 50.331  0 67  ALA   A C     1 ? 
ATOM   555  O  O     . ALA   A 1 67  ? 27.407  7.802   -0.329  1.000 48.173  0 67  ALA   A O     1 ? 
ATOM   556  C  CB    . ALA   A 1 67  ? 29.569  5.594   -1.248  1.000 42.215  0 67  ALA   A CB    1 ? 
ATOM   557  N  N     . THR   A 1 68  ? 27.845  7.940   -2.528  1.000 44.433  0 68  THR   A N     1 ? 
ATOM   558  C  CA    . THR   A 1 68  ? 27.591  9.367   -2.576  1.000 49.312  0 68  THR   A CA    1 ? 
ATOM   559  C  C     . THR   A 1 68  ? 26.086  9.620   -2.390  1.000 50.126  0 68  THR   A C     1 ? 
ATOM   560  O  O     . THR   A 1 68  ? 25.692  10.482  -1.617  1.000 52.599  0 68  THR   A O     1 ? 
ATOM   561  C  CB    . THR   A 1 68  ? 28.123  9.967   -3.876  1.000 44.961  0 68  THR   A CB    1 ? 
ATOM   562  O  OG1   . THR   A 1 68  ? 29.529  9.734   -3.873  1.000 49.921  0 68  THR   A OG1   1 ? 
ATOM   563  C  CG2   . THR   A 1 68  ? 27.943  11.468  -3.936  1.000 44.932  0 68  THR   A CG2   1 ? 
ATOM   564  N  N     . TYR   A 1 69  ? 25.240  8.882   -3.100  1.000 44.094  0 69  TYR   A N     1 ? 
ATOM   565  C  CA    . TYR   A 1 69  ? 23.805  9.005   -2.916  1.000 47.663  0 69  TYR   A CA    1 ? 
ATOM   566  C  C     . TYR   A 1 69  ? 23.460  8.804   -1.439  1.000 47.047  0 69  TYR   A C     1 ? 
ATOM   567  O  O     . TYR   A 1 69  ? 22.784  9.645   -0.847  1.000 48.752  0 69  TYR   A O     1 ? 
ATOM   568  C  CB    . TYR   A 1 69  ? 23.050  8.054   -3.847  1.000 43.556  0 69  TYR   A CB    1 ? 
ATOM   569  C  CG    . TYR   A 1 69  ? 21.545  7.984   -3.623  1.000 42.038  0 69  TYR   A CG    1 ? 
ATOM   570  C  CD1   . TYR   A 1 69  ? 20.712  9.008   -4.033  1.000 47.563  0 69  TYR   A CD1   1 ? 
ATOM   571  C  CD2   . TYR   A 1 69  ? 20.953  6.871   -3.024  1.000 45.021  0 69  TYR   A CD2   1 ? 
ATOM   572  C  CE1   . TYR   A 1 69  ? 19.332  8.932   -3.870  1.000 46.463  0 69  TYR   A CE1   1 ? 
ATOM   573  C  CE2   . TYR   A 1 69  ? 19.586  6.804   -2.815  1.000 53.525  0 69  TYR   A CE2   1 ? 
ATOM   574  C  CZ    . TYR   A 1 69  ? 18.766  7.843   -3.237  1.000 51.565  0 69  TYR   A CZ    1 ? 
ATOM   575  O  OH    . TYR   A 1 69  ? 17.407  7.788   -3.029  1.000 51.660  0 69  TYR   A OH    1 ? 
ATOM   576  N  N     . ASN   A 1 70  ? 23.967  7.731   -0.834  1.000 44.147  0 70  ASN   A N     1 ? 
ATOM   577  C  CA    . ASN   A 1 70  ? 23.607  7.402   0.538   1.000 45.385  0 70  ASN   A CA    1 ? 
ATOM   578  C  C     . ASN   A 1 70  ? 24.113  8.452   1.524   1.000 49.035  0 70  ASN   A C     1 ? 
ATOM   579  O  O     . ASN   A 1 70  ? 23.442  8.769   2.505   1.000 55.946  0 70  ASN   A O     1 ? 
ATOM   580  C  CB    . ASN   A 1 70  ? 24.010  5.967   0.851   1.000 44.882  0 70  ASN   A CB    1 ? 
ATOM   581  C  CG    . ASN   A 1 70  ? 22.977  5.022   0.271   1.000 51.581  0 70  ASN   A CG    1 ? 
ATOM   582  O  OD1   . ASN   A 1 70  ? 21.797  5.086   0.627   1.000 65.616  0 70  ASN   A OD1   1 ? 
ATOM   583  N  ND2   . ASN   A 1 70  ? 23.346  4.183   -0.670  1.000 53.546  0 70  ASN   A ND2   1 ? 
ATOM   584  N  N     . ASN   A 1 71  ? 25.286  9.013   1.250   1.000 51.046  0 71  ASN   A N     1 ? 
ATOM   585  C  CA    . ASN   A 1 71  ? 25.851  10.026  2.129   1.000 51.271  0 71  ASN   A CA    1 ? 
ATOM   586  C  C     . ASN   A 1 71  ? 24.973  11.283  2.123   1.000 47.990  0 71  ASN   A C     1 ? 
ATOM   587  O  O     . ASN   A 1 71  ? 24.749  11.879  3.167   1.000 45.619  0 71  ASN   A O     1 ? 
ATOM   588  C  CB    . ASN   A 1 71  ? 27.291  10.329  1.752   1.000 47.410  0 71  ASN   A CB    1 ? 
ATOM   589  C  CG    . ASN   A 1 71  ? 28.136  10.771  2.914   1.000 49.408  0 71  ASN   A CG    1 ? 
ATOM   590  O  OD1   . ASN   A 1 71  ? 29.196  11.359  2.701   1.000 48.367  0 71  ASN   A OD1   1 ? 
ATOM   591  N  ND2   . ASN   A 1 71  ? 27.670  10.607  4.135   1.000 55.190  0 71  ASN   A ND2   1 ? 
ATOM   592  N  N     . ASP   A 1 72  ? 24.459  11.671  0.958   1.000 41.819  0 72  ASP   A N     1 ? 
ATOM   593  C  CA    . ASP   A 1 72  ? 23.574  12.817  0.842   1.000 42.470  0 72  ASP   A CA    1 ? 
ATOM   594  C  C     . ASP   A 1 72  ? 22.277  12.577  1.609   1.000 44.995  0 72  ASP   A C     1 ? 
ATOM   595  O  O     . ASP   A 1 72  ? 21.839  13.435  2.372   1.000 49.809  0 72  ASP   A O     1 ? 
ATOM   596  C  CB    . ASP   A 1 72  ? 23.283  13.139  -0.603  1.000 47.945  0 72  ASP   A CB    1 ? 
ATOM   597  C  CG    . ASP   A 1 72  ? 24.422  13.800  -1.361  1.000 52.723  0 72  ASP   A CG    1 ? 
ATOM   598  O  OD1   . ASP   A 1 72  ? 25.571  13.861  -0.831  1.000 48.288  0 72  ASP   A OD1   1 ? 
ATOM   599  O  OD2   . ASP   A 1 72  ? 24.140  14.253  -2.479  1.000 57.803  0 72  ASP   A OD2   1 ? 
ATOM   600  N  N     . LEU   A 1 73  ? 21.670  11.400  1.458   1.000 44.888  0 73  LEU   A N     1 ? 
ATOM   601  C  CA    . LEU   A 1 73  ? 20.452  11.111  2.196   1.000 44.511  0 73  LEU   A CA    1 ? 
ATOM   602  C  C     . LEU   A 1 73  ? 20.746  11.213  3.692   1.000 45.399  0 73  LEU   A C     1 ? 
ATOM   603  O  O     . LEU   A 1 73  ? 20.010  11.818  4.466   1.000 43.262  0 73  LEU   A O     1 ? 
ATOM   604  C  CB    . LEU   A 1 73  ? 19.894  9.741   1.853   1.000 48.529  0 73  LEU   A CB    1 ? 
ATOM   605  C  CG    . LEU   A 1 73  ? 19.477  9.496   0.399   1.000 53.013  0 73  LEU   A CG    1 ? 
ATOM   606  C  CD1   . LEU   A 1 73  ? 18.593  8.216   0.335   1.000 59.083  0 73  LEU   A CD1   1 ? 
ATOM   607  C  CD2   . LEU   A 1 73  ? 18.796  10.657  -0.240  1.000 53.958  0 73  LEU   A CD2   1 ? 
ATOM   608  N  N     . ASN   A 1 74  ? 21.862  10.636  4.104   1.000 47.804  0 74  ASN   A N     1 ? 
ATOM   609  C  CA    . ASN   A 1 74  ? 22.298  10.696  5.485   1.000 49.859  0 74  ASN   A CA    1 ? 
ATOM   610  C  C     . ASN   A 1 74  ? 22.515  12.147  5.955   1.000 51.900  0 74  ASN   A C     1 ? 
ATOM   611  O  O     . ASN   A 1 74  ? 22.172  12.531  7.072   1.000 51.703  0 74  ASN   A O     1 ? 
ATOM   612  C  CB    . ASN   A 1 74  ? 23.572  9.888   5.582   1.000 54.128  0 74  ASN   A CB    1 ? 
ATOM   613  C  CG    . ASN   A 1 74  ? 24.131  9.907   6.967   1.000 62.866  0 74  ASN   A CG    1 ? 
ATOM   614  O  OD1   . ASN   A 1 74  ? 25.153  10.559  7.210   1.000 65.897  0 74  ASN   A OD1   1 ? 
ATOM   615  N  ND2   . ASN   A 1 74  ? 23.462  9.186   7.852   1.000 64.710  0 74  ASN   A ND2   1 ? 
ATOM   616  N  N     . GLY   A 1 75  ? 23.107  12.965  5.095   1.000 48.402  0 75  GLY   A N     1 ? 
ATOM   617  C  CA    . GLY   A 1 75  ? 23.308  14.372  5.400   1.000 48.260  0 75  GLY   A CA    1 ? 
ATOM   618  C  C     . GLY   A 1 75  ? 21.980  15.102  5.582   1.000 46.154  0 75  GLY   A C     1 ? 
ATOM   619  O  O     . GLY   A 1 75  ? 21.874  16.009  6.394   1.000 45.889  0 75  GLY   A O     1 ? 
ATOM   620  N  N     . ILE   A 1 76  ? 20.952  14.714  4.824   1.000 48.281  0 76  ILE   A N     1 ? 
ATOM   621  C  CA    . ILE   A 1 76  ? 19.648  15.337  5.014   1.000 48.275  0 76  ILE   A CA    1 ? 
ATOM   622  C  C     . ILE   A 1 76  ? 19.036  14.870  6.328   1.000 47.590  0 76  ILE   A C     1 ? 
ATOM   623  O  O     . ILE   A 1 76  ? 18.578  15.681  7.144   1.000 46.153  0 76  ILE   A O     1 ? 
ATOM   624  C  CB    . ILE   A 1 76  ? 18.712  15.042  3.838   1.000 50.207  0 76  ILE   A CB    1 ? 
ATOM   625  C  CG1   . ILE   A 1 76  ? 19.221  15.679  2.546   1.000 52.688  0 76  ILE   A CG1   1 ? 
ATOM   626  C  CG2   . ILE   A 1 76  ? 17.305  15.496  4.189   1.000 50.562  0 76  ILE   A CG2   1 ? 
ATOM   627  C  CD1   . ILE   A 1 76  ? 18.576  15.164  1.267   1.000 51.165  0 76  ILE   A CD1   1 ? 
ATOM   628  N  N     . LYS   A 1 77  ? 19.046  13.548  6.538   1.000 47.693  0 77  LYS   A N     1 ? 
ATOM   629  C  CA    . LYS   A 1 77  ? 18.294  12.988  7.649   1.000 46.972  0 77  LYS   A CA    1 ? 
ATOM   630  C  C     . LYS   A 1 77  ? 18.948  13.345  8.987   1.000 42.228  0 77  LYS   A C     1 ? 
ATOM   631  O  O     . LYS   A 1 77  ? 18.245  13.514  9.935   1.000 37.410  0 77  LYS   A O     1 ? 
ATOM   632  C  CB    . LYS   A 1 77  ? 18.054  11.483  7.497   1.000 51.758  0 77  LYS   A CB    1 ? 
ATOM   633  C  CG    . LYS   A 1 77  ? 19.143  10.578  7.963   1.000 52.311  0 77  LYS   A CG    1 ? 
ATOM   634  C  CD    . LYS   A 1 77  ? 18.984  9.122   7.505   1.000 53.812  0 77  LYS   A CD    1 ? 
ATOM   635  C  CE    . LYS   A 1 77  ? 20.139  8.390   8.115   1.000 50.604  0 77  LYS   A CE    1 ? 
ATOM   636  N  NZ    . LYS   A 1 77  ? 20.275  6.980   7.821   1.000 56.115  0 77  LYS   A NZ    1 ? 
ATOM   637  N  N     . THR   A 1 78  ? 20.271  13.525  9.082   1.000 46.414  0 78  THR   A N     1 ? 
ATOM   638  C  CA    . THR   A 1 78  ? 20.885  13.801  10.380  1.000 45.977  0 78  THR   A CA    1 ? 
ATOM   639  C  C     . THR   A 1 78  ? 21.067  15.309  10.657  1.000 48.932  0 78  THR   A C     1 ? 
ATOM   640  O  O     . THR   A 1 78  ? 21.649  15.678  11.652  1.000 48.997  0 78  THR   A O     1 ? 
ATOM   641  C  CB    . THR   A 1 78  ? 22.229  13.076  10.433  1.000 48.573  0 78  THR   A CB    1 ? 
ATOM   642  O  OG1   . THR   A 1 78  ? 23.034  13.640  9.394   1.000 48.449  0 78  THR   A OG1   1 ? 
ATOM   643  C  CG2   . THR   A 1 78  ? 22.064  11.579  10.257  1.000 46.077  0 78  THR   A CG2   1 ? 
ATOM   644  N  N     . ASN   A 1 79  ? 20.578  16.207  9.805   1.000 46.901  0 79  ASN   A N     1 ? 
ATOM   645  C  CA    . ASN   A 1 79  ? 20.657  17.634  10.070  1.000 48.610  0 79  ASN   A CA    1 ? 
ATOM   646  C  C     . ASN   A 1 79  ? 19.262  18.231  10.303  1.000 52.676  0 79  ASN   A C     1 ? 
ATOM   647  O  O     . ASN   A 1 79  ? 18.221  17.656  9.962   1.000 50.641  0 79  ASN   A O     1 ? 
ATOM   648  C  CB    . ASN   A 1 79  ? 21.517  18.295  9.000   1.000 53.896  0 79  ASN   A CB    1 ? 
ATOM   649  C  CG    . ASN   A 1 79  ? 22.988  17.953  9.218   1.000 47.784  0 79  ASN   A CG    1 ? 
ATOM   650  O  OD1   . ASN   A 1 79  ? 23.575  18.269  10.261  1.000 58.123  0 79  ASN   A OD1   1 ? 
ATOM   651  N  ND2   . ASN   A 1 79  ? 23.610  17.268  8.275   1.000 48.988  0 79  ASN   A ND2   1 ? 
ATOM   652  N  N     . ASP   A 1 80  ? 19.235  19.397  10.948  1.000 50.244  0 80  ASP   A N     1 ? 
ATOM   653  C  CA    . ASP   A 1 80  ? 17.971  19.922  11.452  1.000 50.023  0 80  ASP   A CA    1 ? 
ATOM   654  C  C     . ASP   A 1 80  ? 17.117  20.439  10.310  1.000 45.058  0 80  ASP   A C     1 ? 
ATOM   655  O  O     . ASP   A 1 80  ? 15.913  20.287  10.333  1.000 54.701  0 80  ASP   A O     1 ? 
ATOM   656  C  CB    . ASP   A 1 80  ? 18.213  20.993  12.498  1.000 56.966  0 80  ASP   A CB    1 ? 
ATOM   657  C  CG    . ASP   A 1 80  ? 19.001  20.505  13.704  1.000 49.394  0 80  ASP   A CG    1 ? 
ATOM   658  O  OD1   . ASP   A 1 80  ? 18.492  19.602  14.384  1.000 53.086  0 80  ASP   A OD1   1 ? 
ATOM   659  O  OD2   . ASP   A 1 80  ? 20.137  20.984  13.903  1.000 50.563  0 80  ASP   A OD2   1 ? 
ATOM   660  N  N     . ILE   A 1 81  ? 17.745  21.035  9.302   1.000 48.996  0 81  ILE   A N     1 ? 
ATOM   661  C  CA    . ILE   A 1 81  ? 17.002  21.818  8.343   1.000 48.967  0 81  ILE   A CA    1 ? 
ATOM   662  C  C     . ILE   A 1 81  ? 17.483  21.552  6.911   1.000 41.738  0 81  ILE   A C     1 ? 
ATOM   663  O  O     . ILE   A 1 81  ? 18.664  21.366  6.669   1.000 43.230  0 81  ILE   A O     1 ? 
ATOM   664  C  CB    . ILE   A 1 81  ? 17.076  23.298  8.773   1.000 50.168  0 81  ILE   A CB    1 ? 
ATOM   665  C  CG1   . ILE   A 1 81  ? 16.180  23.454  10.009  1.000 51.955  0 81  ILE   A CG1   1 ? 
ATOM   666  C  CG2   . ILE   A 1 81  ? 16.674  24.222  7.610   1.000 46.088  0 81  ILE   A CG2   1 ? 
ATOM   667  C  CD1   . ILE   A 1 81  ? 15.924  24.862  10.472  1.000 54.190  0 81  ILE   A CD1   1 ? 
ATOM   668  N  N     . MET   A 1 82  ? 16.528  21.522  5.974   1.000 37.142  0 82  MET   A N     1 ? 
ATOM   669  C  CA    . MET   A 1 82  ? 16.790  21.367  4.552   1.000 44.053  0 82  MET   A CA    1 ? 
ATOM   670  C  C     . MET   A 1 82  ? 16.752  22.723  3.842   1.000 43.820  0 82  MET   A C     1 ? 
ATOM   671  O  O     . MET   A 1 82  ? 15.700  23.377  3.783   1.000 45.334  0 82  MET   A O     1 ? 
ATOM   672  C  CB    . MET   A 1 82  ? 15.710  20.506  3.885   1.000 45.600  0 82  MET   A CB    1 ? 
ATOM   673  C  CG    . MET   A 1 82  ? 15.889  20.356  2.370   1.000 45.703  0 82  MET   A CG    1 ? 
ATOM   674  S  SD    . MET   A 1 82  ? 17.367  19.398  1.994   1.000 49.126  0 82  MET   A SD    1 ? 
ATOM   675  C  CE    . MET   A 1 82  ? 17.395  19.789  0.242   1.000 52.949  0 82  MET   A CE    1 ? 
ATOM   676  N  N     . LEU   A 1 83  ? 17.887  23.064  3.225   1.000 42.388  0 83  LEU   A N     1 ? 
ATOM   677  C  CA    . LEU   A 1 83  ? 18.045  24.289  2.466   1.000 49.082  0 83  LEU   A CA    1 ? 
ATOM   678  C  C     . LEU   A 1 83  ? 18.134  23.934  0.983   1.000 50.652  0 83  LEU   A C     1 ? 
ATOM   679  O  O     . LEU   A 1 83  ? 18.861  23.022  0.590   1.000 45.838  0 83  LEU   A O     1 ? 
ATOM   680  C  CB    . LEU   A 1 83  ? 19.314  25.006  2.910   1.000 50.088  0 83  LEU   A CB    1 ? 
ATOM   681  C  CG    . LEU   A 1 83  ? 19.446  26.447  2.419   1.000 63.987  0 83  LEU   A CG    1 ? 
ATOM   682  C  CD1   . LEU   A 1 83  ? 18.397  27.315  3.112   1.000 70.018  0 83  LEU   A CD1   1 ? 
ATOM   683  C  CD2   . LEU   A 1 83  ? 20.839  26.981  2.648   1.000 65.399  0 83  LEU   A CD2   1 ? 
ATOM   684  N  N     . GLY   A 1 84  ? 17.391  24.678  0.176   1.000 44.787  0 84  GLY   A N     1 ? 
ATOM   685  C  CA    . GLY   A 1 84  ? 17.456  24.549  -1.264  1.000 46.546  0 84  GLY   A CA    1 ? 
ATOM   686  C  C     . GLY   A 1 84  ? 17.777  25.883  -1.927  1.000 47.519  0 84  GLY   A C     1 ? 
ATOM   687  O  O     . GLY   A 1 84  ? 16.902  26.736  -2.075  1.000 50.316  0 84  GLY   A O     1 ? 
ATOM   688  N  N     . VAL   A 1 85  ? 19.021  26.018  -2.386  1.000 44.466  0 85  VAL   A N     1 ? 
ATOM   689  C  CA    . VAL   A 1 85  ? 19.396  27.140  -3.214  1.000 46.642  0 85  VAL   A CA    1 ? 
ATOM   690  C  C     . VAL   A 1 85  ? 18.790  26.915  -4.593  1.000 46.308  0 85  VAL   A C     1 ? 
ATOM   691  O  O     . VAL   A 1 85  ? 19.075  25.928  -5.243  1.000 50.452  0 85  VAL   A O     1 ? 
ATOM   692  C  CB    . VAL   A 1 85  ? 20.920  27.323  -3.278  1.000 49.707  0 85  VAL   A CB    1 ? 
ATOM   693  C  CG1   . VAL   A 1 85  ? 21.292  28.532  -4.131  1.000 47.026  0 85  VAL   A CG1   1 ? 
ATOM   694  C  CG2   . VAL   A 1 85  ? 21.519  27.417  -1.874  1.000 50.266  0 85  VAL   A CG2   1 ? 
ATOM   695  N  N     . TYR   A 1 86  ? 17.982  27.870  -5.034  1.000 43.825  0 86  TYR   A N     1 ? 
ATOM   696  C  CA    . TYR   A 1 86  ? 16.996  27.601  -6.063  1.000 51.681  0 86  TYR   A CA    1 ? 
ATOM   697  C  C     . TYR   A 1 86  ? 16.993  28.711  -7.116  1.000 56.691  0 86  TYR   A C     1 ? 
ATOM   698  O  O     . TYR   A 1 86  ? 16.698  29.860  -6.800  1.000 54.446  0 86  TYR   A O     1 ? 
ATOM   699  C  CB    . TYR   A 1 86  ? 15.654  27.484  -5.339  1.000 44.011  0 86  TYR   A CB    1 ? 
ATOM   700  C  CG    . TYR   A 1 86  ? 14.625  26.757  -6.174  1.000 49.382  0 86  TYR   A CG    1 ? 
ATOM   701  C  CD1   . TYR   A 1 86  ? 13.893  27.429  -7.144  1.000 47.930  0 86  TYR   A CD1   1 ? 
ATOM   702  C  CD2   . TYR   A 1 86  ? 14.388  25.402  -5.985  1.000 44.441  0 86  TYR   A CD2   1 ? 
ATOM   703  C  CE1   . TYR   A 1 86  ? 12.981  26.747  -7.931  1.000 46.407  0 86  TYR   A CE1   1 ? 
ATOM   704  C  CE2   . TYR   A 1 86  ? 13.504  24.713  -6.794  1.000 45.408  0 86  TYR   A CE2   1 ? 
ATOM   705  C  CZ    . TYR   A 1 86  ? 12.787  25.387  -7.756  1.000 46.488  0 86  TYR   A CZ    1 ? 
ATOM   706  O  OH    . TYR   A 1 86  ? 11.884  24.678  -8.506  1.000 44.361  0 86  TYR   A OH    1 ? 
ATOM   707  N  N     . ILE   A 1 87  ? 17.320  28.341  -8.364  1.000 47.923  0 87  ILE   A N     1 ? 
ATOM   708  C  CA    . ILE   A 1 87  ? 17.287  29.236  -9.507  1.000 51.230  0 87  ILE   A CA    1 ? 
ATOM   709  C  C     . ILE   A 1 87  ? 16.055  28.912  -10.336 1.000 49.351  0 87  ILE   A C     1 ? 
ATOM   710  O  O     . ILE   A 1 87  ? 16.002  27.858  -10.966 1.000 54.274  0 87  ILE   A O     1 ? 
ATOM   711  C  CB    . ILE   A 1 87  ? 18.561  29.118  -10.361 1.000 56.977  0 87  ILE   A CB    1 ? 
ATOM   712  C  CG1   . ILE   A 1 87  ? 19.804  29.630  -9.636  1.000 61.491  0 87  ILE   A CG1   1 ? 
ATOM   713  C  CG2   . ILE   A 1 87  ? 18.362  29.914  -11.643 1.000 63.807  0 87  ILE   A CG2   1 ? 
ATOM   714  C  CD1   . ILE   A 1 87  ? 20.173  28.854  -8.400  1.000 79.713  0 87  ILE   A CD1   1 ? 
ATOM   715  N  N     . PRO   A 1 88  ? 15.027  29.787  -10.346 1.000 45.722  0 88  PRO   A N     1 ? 
ATOM   716  C  CA    . PRO   A 1 88  ? 13.768  29.512  -11.054 1.000 49.987  0 88  PRO   A CA    1 ? 
ATOM   717  C  C     . PRO   A 1 88  ? 13.907  29.159  -12.541 1.000 55.144  0 88  PRO   A C     1 ? 
ATOM   718  O  O     . PRO   A 1 88  ? 13.137  28.355  -13.051 1.000 56.441  0 88  PRO   A O     1 ? 
ATOM   719  C  CB    . PRO   A 1 88  ? 13.026  30.837  -10.864 1.000 52.365  0 88  PRO   A CB    1 ? 
ATOM   720  C  CG    . PRO   A 1 88  ? 13.562  31.354  -9.545  1.000 52.885  0 88  PRO   A CG    1 ? 
ATOM   721  C  CD    . PRO   A 1 88  ? 15.031  31.077  -9.647  1.000 49.104  0 88  PRO   A CD    1 ? 
ATOM   722  N  N     . ASP   A 1 89  ? 14.900  29.749  -13.218 1.000 56.092  0 89  ASP   A N     1 ? 
ATOM   723  C  CA    . ASP   A 1 89  ? 15.146  29.482  -14.627 1.000 63.537  0 89  ASP   A CA    1 ? 
ATOM   724  C  C     . ASP   A 1 89  ? 16.034  28.258  -14.826 1.000 55.534  0 89  ASP   A C     1 ? 
ATOM   725  O  O     . ASP   A 1 89  ? 16.201  27.847  -15.957 1.000 53.577  0 89  ASP   A O     1 ? 
ATOM   726  C  CB    . ASP   A 1 89  ? 15.917  30.617  -15.302 1.000 70.921  0 89  ASP   A CB    1 ? 
ATOM   727  C  CG    . ASP   A 1 89  ? 15.314  32.005  -15.208 1.000 70.747  0 89  ASP   A CG    1 ? 
ATOM   728  O  OD1   . ASP   A 1 89  ? 14.285  32.215  -15.857 1.000 81.214  0 89  ASP   A OD1   1 ? 
ATOM   729  O  OD2   . ASP   A 1 89  ? 15.858  32.846  -14.467 1.000 77.242  0 89  ASP   A OD2   1 ? 
ATOM   730  N  N     . GLU   A 1 90  ? 16.668  27.739  -13.769 1.000 56.796  0 90  GLU   A N     1 ? 
ATOM   731  C  CA    . GLU   A 1 90  ? 17.599  26.627  -13.892 1.000 53.680  0 90  GLU   A CA    1 ? 
ATOM   732  C  C     . GLU   A 1 90  ? 17.345  25.646  -12.751 1.000 58.799  0 90  GLU   A C     1 ? 
ATOM   733  O  O     . GLU   A 1 90  ? 18.182  25.408  -11.877 1.000 56.748  0 90  GLU   A O     1 ? 
ATOM   734  C  CB    . GLU   A 1 90  ? 19.042  27.128  -13.848 1.000 58.319  0 90  GLU   A CB    1 ? 
ATOM   735  C  CG    . GLU   A 1 90  ? 19.417  28.138  -14.934 1.000 61.455  0 90  GLU   A CG    1 ? 
ATOM   736  C  CD    . GLU   A 1 90  ? 20.879  28.572  -14.858 1.000 62.934  0 90  GLU   A CD    1 ? 
ATOM   737  O  OE1   . GLU   A 1 90  ? 21.364  29.204  -15.808 1.000 75.947  0 90  GLU   A OE1   1 ? 
ATOM   738  O  OE2   . GLU   A 1 90  ? 21.572  28.253  -13.875 1.000 63.685  0 90  GLU   A OE2   1 ? 
ATOM   739  N  N     . GLU   A 1 91  ? 16.144  25.081  -12.748 1.000 54.014  0 91  GLU   A N     1 ? 
ATOM   740  C  CA    . GLU   A 1 91  ? 15.735  24.222  -11.659 1.000 53.546  0 91  GLU   A CA    1 ? 
ATOM   741  C  C     . GLU   A 1 91  ? 16.474  22.899  -11.783 1.000 53.283  0 91  GLU   A C     1 ? 
ATOM   742  O  O     . GLU   A 1 91  ? 16.810  22.486  -12.881 1.000 54.997  0 91  GLU   A O     1 ? 
ATOM   743  C  CB    . GLU   A 1 91  ? 14.215  24.136  -11.713 1.000 56.671  0 91  GLU   A CB    1 ? 
ATOM   744  C  CG    . GLU   A 1 91  ? 13.515  25.452  -11.381 1.000 56.741  0 91  GLU   A CG    1 ? 
ATOM   745  C  CD    . GLU   A 1 91  ? 12.018  25.459  -11.607 1.000 58.461  0 91  GLU   A CD    1 ? 
ATOM   746  O  OE1   . GLU   A 1 91  ? 11.687  25.181  -12.775 1.000 58.238  0 91  GLU   A OE1   1 ? 
ATOM   747  O  OE2   . GLU   A 1 91  ? 11.200  25.663  -10.659 1.000 60.568  0 91  GLU   A OE2   1 ? 
ATOM   748  N  N     . ASP   A 1 92  ? 16.701  22.228  -10.654 1.000 55.327  0 92  ASP   A N     1 ? 
ATOM   749  C  CA    . ASP   A 1 92  ? 17.555  21.049  -10.620 1.000 48.757  0 92  ASP   A CA    1 ? 
ATOM   750  C  C     . ASP   A 1 92  ? 16.791  19.827  -10.125 1.000 51.106  0 92  ASP   A C     1 ? 
ATOM   751  O  O     . ASP   A 1 92  ? 16.213  19.818  -9.034  1.000 48.566  0 92  ASP   A O     1 ? 
ATOM   752  C  CB    . ASP   A 1 92  ? 18.774  21.271  -9.751  1.000 49.343  0 92  ASP   A CB    1 ? 
ATOM   753  C  CG    . ASP   A 1 92  ? 19.761  20.117  -9.742  1.000 56.721  0 92  ASP   A CG    1 ? 
ATOM   754  O  OD1   . ASP   A 1 92  ? 20.485  19.952  -10.744 1.000 74.205  0 92  ASP   A OD1   1 ? 
ATOM   755  O  OD2   . ASP   A 1 92  ? 19.803  19.410  -8.724  1.000 61.389  0 92  ASP   A OD2   1 ? 
ATOM   756  N  N     . VAL   A 1 93  ? 16.836  18.771  -10.938 1.000 45.511  0 93  VAL   A N     1 ? 
ATOM   757  C  CA    . VAL   A 1 93  ? 16.138  17.537  -10.630 1.000 50.823  0 93  VAL   A CA    1 ? 
ATOM   758  C  C     . VAL   A 1 93  ? 16.679  16.912  -9.340  1.000 46.852  0 93  VAL   A C     1 ? 
ATOM   759  O  O     . VAL   A 1 93  ? 15.915  16.340  -8.580  1.000 46.397  0 93  VAL   A O     1 ? 
ATOM   760  C  CB    . VAL   A 1 93  ? 16.228  16.545  -11.807 1.000 53.225  0 93  VAL   A CB    1 ? 
ATOM   761  C  CG1   . VAL   A 1 93  ? 17.656  16.068  -12.033 1.000 53.537  0 93  VAL   A CG1   1 ? 
ATOM   762  C  CG2   . VAL   A 1 93  ? 15.303  15.355  -11.614 1.000 55.023  0 93  VAL   A CG2   1 ? 
ATOM   763  N  N     . GLY   A 1 94  ? 17.998  16.961  -9.124  1.000 48.667  0 94  GLY   A N     1 ? 
ATOM   764  C  CA    . GLY   A 1 94  ? 18.614  16.359  -7.945  1.000 53.308  0 94  GLY   A CA    1 ? 
ATOM   765  C  C     . GLY   A 1 94  ? 18.087  16.994  -6.663  1.000 52.652  0 94  GLY   A C     1 ? 
ATOM   766  O  O     . GLY   A 1 94  ? 17.670  16.310  -5.737  1.000 44.219  0 94  GLY   A O     1 ? 
ATOM   767  N  N     . LEU   A 1 95  ? 18.062  18.323  -6.659  1.000 48.039  0 95  LEU   A N     1 ? 
ATOM   768  C  CA    . LEU   A 1 95  ? 17.534  19.062  -5.537  1.000 48.286  0 95  LEU   A CA    1 ? 
ATOM   769  C  C     . LEU   A 1 95  ? 16.067  18.721  -5.351  1.000 50.401  0 95  LEU   A C     1 ? 
ATOM   770  O  O     . LEU   A 1 95  ? 15.605  18.603  -4.228  1.000 51.642  0 95  LEU   A O     1 ? 
ATOM   771  C  CB    . LEU   A 1 95  ? 17.709  20.556  -5.787  1.000 48.759  0 95  LEU   A CB    1 ? 
ATOM   772  C  CG    . LEU   A 1 95  ? 17.152  21.476  -4.706  1.000 48.352  0 95  LEU   A CG    1 ? 
ATOM   773  C  CD1   . LEU   A 1 95  ? 17.711  21.083  -3.355  1.000 44.630  0 95  LEU   A CD1   1 ? 
ATOM   774  C  CD2   . LEU   A 1 95  ? 17.443  22.944  -5.035  1.000 52.057  0 95  LEU   A CD2   1 ? 
ATOM   775  N  N     . GLY   A 1 96  ? 15.323  18.628  -6.451  1.000 48.574  0 96  GLY   A N     1 ? 
ATOM   776  C  CA    . GLY   A 1 96  ? 13.924  18.261  -6.356  1.000 49.077  0 96  GLY   A CA    1 ? 
ATOM   777  C  C     . GLY   A 1 96  ? 13.749  16.980  -5.544  1.000 52.695  0 96  GLY   A C     1 ? 
ATOM   778  O  O     . GLY   A 1 96  ? 12.958  16.948  -4.603  1.000 45.189  0 96  GLY   A O     1 ? 
ATOM   779  N  N     . MET   A 1 97  ? 14.532  15.949  -5.897  1.000 50.381  0 97  MET   A N     1 ? 
ATOM   780  C  CA    . MET   A 1 97  ? 14.468  14.676  -5.202  1.000 49.203  0 97  MET   A CA    1 ? 
ATOM   781  C  C     . MET   A 1 97  ? 14.748  14.873  -3.706  1.000 47.680  0 97  MET   A C     1 ? 
ATOM   782  O  O     . MET   A 1 97  ? 14.032  14.371  -2.849  1.000 43.727  0 97  MET   A O     1 ? 
ATOM   783  C  CB    . MET   A 1 97  ? 15.459  13.703  -5.833  1.000 46.510  0 97  MET   A CB    1 ? 
ATOM   784  C  CG    . MET   A 1 97  ? 15.442  12.302  -5.191  1.000 52.842  0 97  MET   A CG    1 ? 
ATOM   785  S  SD    . MET   A 1 97  ? 16.511  12.317  -3.744  1.000 50.981  0 97  MET   A SD    1 ? 
ATOM   786  C  CE    . MET   A 1 97  ? 15.923  10.859  -2.880  1.000 51.441  0 97  MET   A CE    1 ? 
ATOM   787  N  N     . GLU   A 1 98  ? 15.804  15.619  -3.403  1.000 45.970  0 98  GLU   A N     1 ? 
ATOM   788  C  CA    . GLU   A 1 98  ? 16.238  15.854  -2.037  1.000 44.499  0 98  GLU   A CA    1 ? 
ATOM   789  C  C     . GLU   A 1 98  ? 15.185  16.610  -1.232  1.000 45.093  0 98  GLU   A C     1 ? 
ATOM   790  O  O     . GLU   A 1 98  ? 15.030  16.355  -0.038  1.000 48.452  0 98  GLU   A O     1 ? 
ATOM   791  C  CB    . GLU   A 1 98  ? 17.508  16.695  -2.045  1.000 41.889  0 98  GLU   A CB    1 ? 
ATOM   792  C  CG    . GLU   A 1 98  ? 18.731  15.947  -2.556  1.000 51.364  0 98  GLU   A CG    1 ? 
ATOM   793  C  CD    . GLU   A 1 98  ? 19.885  16.859  -2.932  1.000 60.308  0 98  GLU   A CD    1 ? 
ATOM   794  O  OE1   . GLU   A 1 98  ? 19.783  18.124  -3.017  1.000 52.747  0 98  GLU   A OE1   1 ? 
ATOM   795  O  OE2   . GLU   A 1 98  ? 20.926  16.223  -3.124  1.000 59.651  0 98  GLU   A OE2   1 ? 
ATOM   796  N  N     . LEU   A 1 99  ? 14.457  17.528  -1.885  1.000 48.595  0 99  LEU   A N     1 ? 
ATOM   797  C  CA    . LEU   A 1 99  ? 13.342  18.216  -1.235  1.000 48.698  0 99  LEU   A CA    1 ? 
ATOM   798  C  C     . LEU   A 1 99  ? 12.290  17.204  -0.789  1.000 51.330  0 99  LEU   A C     1 ? 
ATOM   799  O  O     . LEU   A 1 99  ? 11.801  17.248  0.336   1.000 50.761  0 99  LEU   A O     1 ? 
ATOM   800  C  CB    . LEU   A 1 99  ? 12.735  19.265  -2.156  1.000 46.154  0 99  LEU   A CB    1 ? 
ATOM   801  C  CG    . LEU   A 1 99  ? 13.644  20.428  -2.566  1.000 47.242  0 99  LEU   A CG    1 ? 
ATOM   802  C  CD1   . LEU   A 1 99  ? 12.962  21.316  -3.587  1.000 51.845  0 99  LEU   A CD1   1 ? 
ATOM   803  C  CD2   . LEU   A 1 99  ? 14.057  21.261  -1.360  1.000 50.324  0 99  LEU   A CD2   1 ? 
ATOM   804  N  N     . GLY   A 1 100 ? 11.967  16.266  -1.679  1.000 52.692  0 100 GLY   A N     1 ? 
ATOM   805  C  CA    . GLY   A 1 100 ? 10.996  15.227  -1.384  1.000 52.042  0 100 GLY   A CA    1 ? 
ATOM   806  C  C     . GLY   A 1 100 ? 11.480  14.307  -0.267  1.000 47.044  0 100 GLY   A C     1 ? 
ATOM   807  O  O     . GLY   A 1 100 ? 10.699  13.931  0.576   1.000 46.288  0 100 GLY   A O     1 ? 
ATOM   808  N  N     . TYR   A 1 101 ? 12.781  13.996  -0.229  1.000 42.802  0 101 TYR   A N     1 ? 
ATOM   809  C  CA    . TYR   A 1 101 ? 13.303  13.165  0.836   1.000 48.991  0 101 TYR   A CA    1 ? 
ATOM   810  C  C     . TYR   A 1 101 ? 13.216  13.939  2.155   1.000 49.951  0 101 TYR   A C     1 ? 
ATOM   811  O  O     . TYR   A 1 101 ? 12.770  13.387  3.161   1.000 48.365  0 101 TYR   A O     1 ? 
ATOM   812  C  CB    . TYR   A 1 101 ? 14.675  12.626  0.423   1.000 47.520  0 101 TYR   A CB    1 ? 
ATOM   813  C  CG    . TYR   A 1 101 ? 15.276  11.695  1.461   1.000 48.772  0 101 TYR   A CG    1 ? 
ATOM   814  C  CD1   . TYR   A 1 101 ? 14.907  10.354  1.585   1.000 53.831  0 101 TYR   A CD1   1 ? 
ATOM   815  C  CD2   . TYR   A 1 101 ? 16.192  12.193  2.370   1.000 51.740  0 101 TYR   A CD2   1 ? 
ATOM   816  C  CE1   . TYR   A 1 101 ? 15.474  9.531   2.556   1.000 47.678  0 101 TYR   A CE1   1 ? 
ATOM   817  C  CE2   . TYR   A 1 101 ? 16.736  11.400  3.363   1.000 50.115  0 101 TYR   A CE2   1 ? 
ATOM   818  C  CZ    . TYR   A 1 101 ? 16.385  10.069  3.458   1.000 53.434  0 101 TYR   A CZ    1 ? 
ATOM   819  O  OH    . TYR   A 1 101 ? 17.016  9.393   4.465   1.000 55.057  0 101 TYR   A OH    1 ? 
ATOM   820  N  N     . ALA   A 1 102 ? 13.609  15.219  2.134   1.000 46.496  0 102 ALA   A N     1 ? 
ATOM   821  C  CA    . ALA   A 1 102 ? 13.569  16.057  3.326   1.000 44.280  0 102 ALA   A CA    1 ? 
ATOM   822  C  C     . ALA   A 1 102 ? 12.161  16.112  3.911   1.000 45.126  0 102 ALA   A C     1 ? 
ATOM   823  O  O     . ALA   A 1 102 ? 11.993  15.976  5.116   1.000 47.278  0 102 ALA   A O     1 ? 
ATOM   824  C  CB    . ALA   A 1 102 ? 14.059  17.450  3.003   1.000 49.553  0 102 ALA   A CB    1 ? 
ATOM   825  N  N     . LEU   A 1 103 ? 11.154  16.304  3.051   1.000 53.436  0 103 LEU   A N     1 ? 
ATOM   826  C  CA    . LEU   A 1 103 ? 9.761   16.280  3.459   1.000 54.077  0 103 LEU   A CA    1 ? 
ATOM   827  C  C     . LEU   A 1 103 ? 9.475   14.971  4.183   1.000 52.678  0 103 LEU   A C     1 ? 
ATOM   828  O  O     . LEU   A 1 103 ? 8.929   14.961  5.274   1.000 53.497  0 103 LEU   A O     1 ? 
ATOM   829  C  CB    . LEU   A 1 103 ? 8.819   16.416  2.273   1.000 53.977  0 103 LEU   A CB    1 ? 
ATOM   830  C  CG    . LEU   A 1 103 ? 7.334   16.170  2.578   1.000 66.880  0 103 LEU   A CG    1 ? 
ATOM   831  C  CD1   . LEU   A 1 103 ? 6.771   17.331  3.395   1.000 63.861  0 103 LEU   A CD1   1 ? 
ATOM   832  C  CD2   . LEU   A 1 103 ? 6.504   15.926  1.308   1.000 64.917  0 103 LEU   A CD2   1 ? 
ATOM   833  N  N     . SER   A 1 104 ? 9.883   13.869  3.575   1.000 53.922  0 104 SER   A N     1 ? 
ATOM   834  C  CA    . SER   A 1 104 ? 9.612   12.566  4.154   1.000 56.540  0 104 SER   A CA    1 ? 
ATOM   835  C  C     . SER   A 1 104 ? 10.321  12.405  5.498   1.000 53.973  0 104 SER   A C     1 ? 
ATOM   836  O  O     . SER   A 1 104 ? 9.942   11.547  6.285   1.000 47.381  0 104 SER   A O     1 ? 
ATOM   837  C  CB    . SER   A 1 104 ? 10.026  11.470  3.217   1.000 56.541  0 104 SER   A CB    1 ? 
ATOM   838  O  OG    . SER   A 1 104 ? 11.418  11.183  3.325   1.000 62.550  0 104 SER   A OG    1 ? 
ATOM   839  N  N     . GLN   A 1 105 ? 11.407  13.159  5.733   1.000 47.348  0 105 GLN   A N     1 ? 
ATOM   840  C  CA    . GLN   A 1 105 ? 12.130  12.980  6.980   1.000 48.783  0 105 GLN   A CA    1 ? 
ATOM   841  C  C     . GLN   A 1 105 ? 11.707  14.016  8.014   1.000 46.302  0 105 GLN   A C     1 ? 
ATOM   842  O  O     . GLN   A 1 105 ? 12.347  14.123  9.056   1.000 49.571  0 105 GLN   A O     1 ? 
ATOM   843  C  CB    . GLN   A 1 105 ? 13.643  13.069  6.757   1.000 53.885  0 105 GLN   A CB    1 ? 
ATOM   844  C  CG    . GLN   A 1 105 ? 14.205  11.927  5.929   1.000 47.311  0 105 GLN   A CG    1 ? 
ATOM   845  C  CD    . GLN   A 1 105 ? 14.079  10.598  6.631   1.000 53.764  0 105 GLN   A CD    1 ? 
ATOM   846  O  OE1   . GLN   A 1 105 ? 14.419  10.472  7.803   1.000 48.686  0 105 GLN   A OE1   1 ? 
ATOM   847  N  NE2   . GLN   A 1 105 ? 13.630  9.587   5.914   1.000 52.456  0 105 GLN   A NE2   1 ? 
ATOM   848  N  N     . GLY   A 1 106 ? 10.634  14.765  7.747   1.000 42.715  0 106 GLY   A N     1 ? 
ATOM   849  C  CA    . GLY   A 1 106 ? 10.105  15.722  8.703   1.000 46.230  0 106 GLY   A CA    1 ? 
ATOM   850  C  C     . GLY   A 1 106 ? 10.937  16.993  8.867   1.000 46.081  0 106 GLY   A C     1 ? 
ATOM   851  O  O     . GLY   A 1 106 ? 10.884  17.613  9.917   1.000 53.816  0 106 GLY   A O     1 ? 
ATOM   852  N  N     . LYS   A 1 107 ? 11.686  17.397  7.839   1.000 49.085  0 107 LYS   A N     1 ? 
ATOM   853  C  CA    . LYS   A 1 107 ? 12.559  18.561  7.943   1.000 46.378  0 107 LYS   A CA    1 ? 
ATOM   854  C  C     . LYS   A 1 107 ? 11.839  19.803  7.449   1.000 47.188  0 107 LYS   A C     1 ? 
ATOM   855  O  O     . LYS   A 1 107 ? 11.088  19.743  6.480   1.000 44.567  0 107 LYS   A O     1 ? 
ATOM   856  C  CB    . LYS   A 1 107 ? 13.793  18.415  7.039   1.000 48.167  0 107 LYS   A CB    1 ? 
ATOM   857  C  CG    . LYS   A 1 107 ? 14.632  17.164  7.301   1.000 45.624  0 107 LYS   A CG    1 ? 
ATOM   858  C  CD    . LYS   A 1 107 ? 15.109  17.063  8.743   1.000 43.536  0 107 LYS   A CD    1 ? 
ATOM   859  C  CE    . LYS   A 1 107 ? 15.631  15.677  9.023   1.000 45.380  0 107 LYS   A CE    1 ? 
ATOM   860  N  NZ    . LYS   A 1 107 ? 16.337  15.632  10.304  1.000 45.288  0 107 LYS   A NZ    1 ? 
ATOM   861  N  N     . TYR   A 1 108 ? 12.135  20.935  8.086   1.000 47.307  0 108 TYR   A N     1 ? 
ATOM   862  C  CA    . TYR   A 1 108 ? 11.787  22.233  7.555   1.000 46.254  0 108 TYR   A CA    1 ? 
ATOM   863  C  C     . TYR   A 1 108 ? 12.496  22.387  6.218   1.000 49.443  0 108 TYR   A C     1 ? 
ATOM   864  O  O     . TYR   A 1 108 ? 13.683  22.107  6.100   1.000 49.626  0 108 TYR   A O     1 ? 
ATOM   865  C  CB    . TYR   A 1 108 ? 12.194  23.370  8.490   1.000 48.642  0 108 TYR   A CB    1 ? 
ATOM   866  C  CG    . TYR   A 1 108 ? 11.699  24.757  8.080   1.000 44.909  0 108 TYR   A CG    1 ? 
ATOM   867  C  CD1   . TYR   A 1 108 ? 10.352  25.068  8.152   1.000 46.198  0 108 TYR   A CD1   1 ? 
ATOM   868  C  CD2   . TYR   A 1 108 ? 12.569  25.768  7.688   1.000 43.966  0 108 TYR   A CD2   1 ? 
ATOM   869  C  CE1   . TYR   A 1 108 ? 9.880   26.331  7.831   1.000 48.096  0 108 TYR   A CE1   1 ? 
ATOM   870  C  CE2   . TYR   A 1 108 ? 12.109  27.051  7.387   1.000 44.547  0 108 TYR   A CE2   1 ? 
ATOM   871  C  CZ    . TYR   A 1 108 ? 10.761  27.338  7.479   1.000 41.683  0 108 TYR   A CZ    1 ? 
ATOM   872  O  OH    . TYR   A 1 108 ? 10.262  28.588  7.215   1.000 44.122  0 108 TYR   A OH    1 ? 
ATOM   873  N  N     . VAL   A 1 109 ? 11.725  22.766  5.206   1.000 47.806  0 109 VAL   A N     1 ? 
ATOM   874  C  CA    . VAL   A 1 109 ? 12.218  22.864  3.848   1.000 45.257  0 109 VAL   A CA    1 ? 
ATOM   875  C  C     . VAL   A 1 109 ? 12.156  24.333  3.427   1.000 42.969  0 109 VAL   A C     1 ? 
ATOM   876  O  O     . VAL   A 1 109 ? 11.081  24.861  3.164   1.000 45.998  0 109 VAL   A O     1 ? 
ATOM   877  C  CB    . VAL   A 1 109 ? 11.450  21.963  2.865   1.000 44.810  0 109 VAL   A CB    1 ? 
ATOM   878  C  CG1   . VAL   A 1 109 ? 12.008  22.116  1.472   1.000 44.019  0 109 VAL   A CG1   1 ? 
ATOM   879  C  CG2   . VAL   A 1 109 ? 11.483  20.504  3.272   1.000 46.256  0 109 VAL   A CG2   1 ? 
ATOM   880  N  N     . LEU   A 1 110 ? 13.334  24.952  3.330   1.000 43.566  0 110 LEU   A N     1 ? 
ATOM   881  C  CA    . LEU   A 1 110 ? 13.475  26.363  3.031   1.000 50.844  0 110 LEU   A CA    1 ? 
ATOM   882  C  C     . LEU   A 1 110 ? 14.150  26.509  1.675   1.000 46.286  0 110 LEU   A C     1 ? 
ATOM   883  O  O     . LEU   A 1 110 ? 15.293  26.064  1.502   1.000 53.813  0 110 LEU   A O     1 ? 
ATOM   884  C  CB    . LEU   A 1 110 ? 14.364  26.978  4.108   1.000 49.715  0 110 LEU   A CB    1 ? 
ATOM   885  C  CG    . LEU   A 1 110 ? 14.187  28.465  4.421   1.000 50.822  0 110 LEU   A CG    1 ? 
ATOM   886  C  CD1   . LEU   A 1 110 ? 15.518  29.128  4.539   1.000 49.648  0 110 LEU   A CD1   1 ? 
ATOM   887  C  CD2   . LEU   A 1 110 ? 13.272  29.259  3.571   1.000 54.234  0 110 LEU   A CD2   1 ? 
ATOM   888  N  N     . LEU   A 1 111 ? 13.452  27.140  0.727   1.000 42.776  0 111 LEU   A N     1 ? 
ATOM   889  C  CA    . LEU   A 1 111 ? 14.104  27.555  -0.515  1.000 46.525  0 111 LEU   A CA    1 ? 
ATOM   890  C  C     . LEU   A 1 111 ? 14.646  28.990  -0.376  1.000 46.513  0 111 LEU   A C     1 ? 
ATOM   891  O  O     . LEU   A 1 111 ? 14.016  29.854  0.204   1.000 47.244  0 111 LEU   A O     1 ? 
ATOM   892  C  CB    . LEU   A 1 111 ? 13.152  27.431  -1.696  1.000 48.706  0 111 LEU   A CB    1 ? 
ATOM   893  C  CG    . LEU   A 1 111 ? 12.409  26.098  -1.869  1.000 47.262  0 111 LEU   A CG    1 ? 
ATOM   894  C  CD1   . LEU   A 1 111 ? 11.517  26.219  -3.098  1.000 45.976  0 111 LEU   A CD1   1 ? 
ATOM   895  C  CD2   . LEU   A 1 111 ? 13.359  24.914  -1.985  1.000 53.739  0 111 LEU   A CD2   1 ? 
ATOM   896  N  N     . VAL   A 1 112 ? 15.816  29.233  -0.948  1.000 44.835  0 112 VAL   A N     1 ? 
ATOM   897  C  CA    . VAL   A 1 112 ? 16.415  30.542  -1.085  1.000 50.297  0 112 VAL   A CA    1 ? 
ATOM   898  C  C     . VAL   A 1 112 ? 16.664  30.840  -2.572  1.000 53.025  0 112 VAL   A C     1 ? 
ATOM   899  O  O     . VAL   A 1 112 ? 17.418  30.131  -3.241  1.000 48.410  0 112 VAL   A O     1 ? 
ATOM   900  C  CB    . VAL   A 1 112 ? 17.764  30.621  -0.353  1.000 54.021  0 112 VAL   A CB    1 ? 
ATOM   901  C  CG1   . VAL   A 1 112 ? 18.172  32.076  -0.184  1.000 56.526  0 112 VAL   A CG1   1 ? 
ATOM   902  C  CG2   . VAL   A 1 112 ? 17.741  29.932  0.985   1.000 66.375  0 112 VAL   A CG2   1 ? 
ATOM   903  N  N     . ILE   A 1 113 ? 16.165  31.986  -3.019  1.000 49.580  0 113 ILE   A N     1 ? 
ATOM   904  C  CA    . ILE   A 1 113 ? 16.256  32.432  -4.396  1.000 44.626  0 113 ILE   A CA    1 ? 
ATOM   905  C  C     . ILE   A 1 113 ? 17.014  33.749  -4.440  1.000 50.273  0 113 ILE   A C     1 ? 
ATOM   906  O  O     . ILE   A 1 113 ? 16.726  34.664  -3.655  1.000 47.501  0 113 ILE   A O     1 ? 
ATOM   907  C  CB    . ILE   A 1 113 ? 14.845  32.578  -4.966  1.000 49.919  0 113 ILE   A CB    1 ? 
ATOM   908  C  CG1   . ILE   A 1 113 ? 14.109  31.231  -4.946  1.000 46.038  0 113 ILE   A CG1   1 ? 
ATOM   909  C  CG2   . ILE   A 1 113 ? 14.879  33.211  -6.360  1.000 51.543  0 113 ILE   A CG2   1 ? 
ATOM   910  C  CD1   . ILE   A 1 113 ? 12.658  31.309  -5.382  1.000 47.522  0 113 ILE   A CD1   1 ? 
ATOM   911  N  N     . PRO   A 1 114 ? 18.016  33.880  -5.342  1.000 51.199  0 114 PRO   A N     1 ? 
ATOM   912  C  CA    . PRO   A 1 114 ? 18.691  35.151  -5.587  1.000 49.050  0 114 PRO   A CA    1 ? 
ATOM   913  C  C     . PRO   A 1 114 ? 17.688  36.289  -5.683  1.000 48.657  0 114 PRO   A C     1 ? 
ATOM   914  O  O     . PRO   A 1 114 ? 16.620  36.117  -6.283  1.000 46.705  0 114 PRO   A O     1 ? 
ATOM   915  C  CB    . PRO   A 1 114 ? 19.420  34.940  -6.914  1.000 52.864  0 114 PRO   A CB    1 ? 
ATOM   916  C  CG    . PRO   A 1 114 ? 19.651  33.451  -6.971  1.000 55.779  0 114 PRO   A CG    1 ? 
ATOM   917  C  CD    . PRO   A 1 114 ? 18.533  32.811  -6.195  1.000 53.205  0 114 PRO   A CD    1 ? 
ATOM   918  N  N     . ASP   A 1 115 ? 18.046  37.431  -5.073  1.000 53.788  0 115 ASP   A N     1 ? 
ATOM   919  C  CA    . ASP   A 1 115 ? 17.148  38.581  -5.016  1.000 57.919  0 115 ASP   A CA    1 ? 
ATOM   920  C  C     . ASP   A 1 115 ? 16.735  38.971  -6.432  1.000 52.038  0 115 ASP   A C     1 ? 
ATOM   921  O  O     . ASP   A 1 115 ? 15.578  39.296  -6.663  1.000 50.249  0 115 ASP   A O     1 ? 
ATOM   922  C  CB    . ASP   A 1 115 ? 17.746  39.767  -4.269  1.000 57.101  0 115 ASP   A CB    1 ? 
ATOM   923  C  CG    . ASP   A 1 115 ? 17.956  39.575  -2.770  1.000 55.634  0 115 ASP   A CG    1 ? 
ATOM   924  O  OD1   . ASP   A 1 115 ? 18.709  38.675  -2.390  1.000 64.545  0 115 ASP   A OD1   1 ? 
ATOM   925  O  OD2   . ASP   A 1 115 ? 17.344  40.316  -1.980  1.000 66.485  0 115 ASP   A OD2   1 ? 
ATOM   926  N  N     . GLU   A 1 116 ? 17.667  38.888  -7.387  1.000 60.120  0 116 GLU   A N     1 ? 
ATOM   927  C  CA    . GLU   A 1 116 ? 17.393  39.283  -8.768  1.000 64.896  0 116 GLU   A CA    1 ? 
ATOM   928  C  C     . GLU   A 1 116 ? 16.335  38.370  -9.407  1.000 59.346  0 116 GLU   A C     1 ? 
ATOM   929  O  O     . GLU   A 1 116 ? 15.699  38.764  -10.383 1.000 53.485  0 116 GLU   A O     1 ? 
ATOM   930  C  CB    . GLU   A 1 116 ? 18.682  39.376  -9.596  1.000 66.541  0 116 GLU   A CB    1 ? 
ATOM   931  C  CG    . GLU   A 1 116 ? 19.618  38.169  -9.471  1.000 79.267  0 116 GLU   A CG    1 ? 
ATOM   932  C  CD    . GLU   A 1 116 ? 20.645  38.171  -8.324  1.000 86.056  0 116 GLU   A CD    1 ? 
ATOM   933  O  OE1   . GLU   A 1 116 ? 20.352  38.559  -7.145  1.000 62.688  0 116 GLU   A OE1   1 ? 
ATOM   934  O  OE2   . GLU   A 1 116 ? 21.789  37.726  -8.620  1.000 73.388  0 116 GLU   A OE2   1 ? 
ATOM   935  N  N     . ASP   A 1 117 ? 16.109  37.169  -8.851  1.000 55.337  0 117 ASP   A N     1 ? 
ATOM   936  C  CA    . ASP   A 1 117 ? 15.138  36.240  -9.421  1.000 57.897  0 117 ASP   A CA    1 ? 
ATOM   937  C  C     . ASP   A 1 117 ? 13.889  36.072  -8.553  1.000 54.659  0 117 ASP   A C     1 ? 
ATOM   938  O  O     . ASP   A 1 117 ? 12.918  35.424  -8.983  1.000 52.911  0 117 ASP   A O     1 ? 
ATOM   939  C  CB    . ASP   A 1 117 ? 15.772  34.883  -9.702  1.000 59.843  0 117 ASP   A CB    1 ? 
ATOM   940  C  CG    . ASP   A 1 117 ? 17.004  34.910  -10.604 1.000 59.286  0 117 ASP   A CG    1 ? 
ATOM   941  O  OD1   . ASP   A 1 117 ? 17.031  35.736  -11.548 1.000 58.484  0 117 ASP   A OD1   1 ? 
ATOM   942  O  OD2   . ASP   A 1 117 ? 17.933  34.095  -10.378 1.000 63.967  0 117 ASP   A OD2   1 ? 
ATOM   943  N  N     . TYR   A 1 118 ? 13.903  36.610  -7.324  1.000 58.430  0 118 TYR   A N     1 ? 
ATOM   944  C  CA    . TYR   A 1 118 ? 12.810  36.341  -6.391  1.000 58.639  0 118 TYR   A CA    1 ? 
ATOM   945  C  C     . TYR   A 1 118 ? 11.530  36.891  -7.005  1.000 55.837  0 118 TYR   A C     1 ? 
ATOM   946  O  O     . TYR   A 1 118 ? 11.511  38.060  -7.385  1.000 54.472  0 118 TYR   A O     1 ? 
ATOM   947  C  CB    . TYR   A 1 118 ? 12.999  36.939  -4.988  1.000 59.572  0 118 TYR   A CB    1 ? 
ATOM   948  C  CG    . TYR   A 1 118 ? 12.001  36.444  -3.948  1.000 63.783  0 118 TYR   A CG    1 ? 
ATOM   949  C  CD1   . TYR   A 1 118 ? 10.767  37.070  -3.756  1.000 61.935  0 118 TYR   A CD1   1 ? 
ATOM   950  C  CD2   . TYR   A 1 118 ? 12.273  35.321  -3.178  1.000 55.846  0 118 TYR   A CD2   1 ? 
ATOM   951  C  CE1   . TYR   A 1 118 ? 9.842   36.583  -2.842  1.000 67.775  0 118 TYR   A CE1   1 ? 
ATOM   952  C  CE2   . TYR   A 1 118 ? 11.357  34.837  -2.251  1.000 54.790  0 118 TYR   A CE2   1 ? 
ATOM   953  C  CZ    . TYR   A 1 118 ? 10.141  35.468  -2.069  1.000 67.455  0 118 TYR   A CZ    1 ? 
ATOM   954  O  OH    . TYR   A 1 118 ? 9.259   34.944  -1.149  1.000 73.033  0 118 TYR   A OH    1 ? 
ATOM   955  N  N     . GLY   A 1 119 ? 10.492  36.046  -7.104  1.000 58.512  0 119 GLY   A N     1 ? 
ATOM   956  C  CA    . GLY   A 1 119 ? 9.222   36.431  -7.718  1.000 56.905  0 119 GLY   A CA    1 ? 
ATOM   957  C  C     . GLY   A 1 119 ? 8.938   35.699  -9.033  1.000 50.874  0 119 GLY   A C     1 ? 
ATOM   958  O  O     . GLY   A 1 119 ? 7.778   35.567  -9.426  1.000 51.548  0 119 GLY   A O     1 ? 
ATOM   959  N  N     . LYS   A 1 120 ? 9.999   35.251  -9.727  1.000 53.495  0 120 LYS   A N     1 ? 
ATOM   960  C  CA    . LYS   A 1 120 ? 9.852   34.493  -10.952 1.000 60.310  0 120 LYS   A CA    1 ? 
ATOM   961  C  C     . LYS   A 1 120 ? 9.124   33.178  -10.670 1.000 57.458  0 120 LYS   A C     1 ? 
ATOM   962  O  O     . LYS   A 1 120 ? 9.139   32.670  -9.559  1.000 53.238  0 120 LYS   A O     1 ? 
ATOM   963  C  CB    . LYS   A 1 120 ? 11.177  34.178  -11.651 1.000 60.772  0 120 LYS   A CB    1 ? 
ATOM   964  C  CG    . LYS   A 1 120 ? 12.006  35.371  -12.122 1.000 73.419  0 120 LYS   A CG    1 ? 
ATOM   965  C  CD    . LYS   A 1 120 ? 12.834  35.099  -13.383 1.000 86.074  0 120 LYS   A CD    1 ? 
ATOM   966  C  CE    . LYS   A 1 120 ? 14.315  35.402  -13.429 1.000 81.692  0 120 LYS   A CE    1 ? 
ATOM   967  N  NZ    . LYS   A 1 120 ? 14.747  36.741  -13.057 1.000 70.975  0 120 LYS   A NZ    1 ? 
ATOM   968  N  N     . PRO   A 1 121 ? 8.399   32.614  -11.656 1.000 55.581  0 121 PRO   A N     1 ? 
ATOM   969  C  CA    . PRO   A 1 121 ? 7.601   31.423  -11.403 1.000 51.299  0 121 PRO   A CA    1 ? 
ATOM   970  C  C     . PRO   A 1 121 ? 8.502   30.254  -11.037 1.000 49.256  0 121 PRO   A C     1 ? 
ATOM   971  O  O     . PRO   A 1 121 ? 9.591   30.123  -11.584 1.000 57.164  0 121 PRO   A O     1 ? 
ATOM   972  C  CB    . PRO   A 1 121 ? 6.846   31.182  -12.746 1.000 56.861  0 121 PRO   A CB    1 ? 
ATOM   973  C  CG    . PRO   A 1 121 ? 6.982   32.477  -13.535 1.000 55.234  0 121 PRO   A CG    1 ? 
ATOM   974  C  CD    . PRO   A 1 121 ? 8.237   33.155  -13.021 1.000 51.063  0 121 PRO   A CD    1 ? 
ATOM   975  N  N     . ILE   A 1 122 ? 8.027   29.388  -10.130 1.000 50.766  0 122 ILE   A N     1 ? 
ATOM   976  C  CA    . ILE   A 1 122 ? 8.725   28.148  -9.798  1.000 49.150  0 122 ILE   A CA    1 ? 
ATOM   977  C  C     . ILE   A 1 122 ? 7.784   26.983  -9.986  1.000 42.805  0 122 ILE   A C     1 ? 
ATOM   978  O  O     . ILE   A 1 122 ? 6.576   27.160  -9.980  1.000 47.886  0 122 ILE   A O     1 ? 
ATOM   979  C  CB    . ILE   A 1 122 ? 9.302   28.169  -8.376  1.000 49.771  0 122 ILE   A CB    1 ? 
ATOM   980  C  CG1   . ILE   A 1 122 ? 8.200   28.131  -7.328  1.000 54.135  0 122 ILE   A CG1   1 ? 
ATOM   981  C  CG2   . ILE   A 1 122 ? 10.223  29.370  -8.197  1.000 49.978  0 122 ILE   A CG2   1 ? 
ATOM   982  C  CD1   . ILE   A 1 122 ? 8.719   28.180  -5.902  1.000 54.880  0 122 ILE   A CD1   1 ? 
ATOM   983  N  N     . ASN   A 1 123 ? 8.359   25.800  -10.210 1.000 50.357  0 123 ASN   A N     1 ? 
ATOM   984  C  CA    . ASN   A 1 123 ? 7.565   24.592  -10.378 1.000 45.822  0 123 ASN   A CA    1 ? 
ATOM   985  C  C     . ASN   A 1 123 ? 6.596   24.457  -9.217  1.000 47.998  0 123 ASN   A C     1 ? 
ATOM   986  O  O     . ASN   A 1 123 ? 6.964   24.675  -8.064  1.000 51.877  0 123 ASN   A O     1 ? 
ATOM   987  C  CB    . ASN   A 1 123 ? 8.472   23.375  -10.427 1.000 51.533  0 123 ASN   A CB    1 ? 
ATOM   988  C  CG    . ASN   A 1 123 ? 7.763   22.164  -10.953 1.000 54.042  0 123 ASN   A CG    1 ? 
ATOM   989  O  OD1   . ASN   A 1 123 ? 6.966   21.554  -10.233 1.000 53.234  0 123 ASN   A OD1   1 ? 
ATOM   990  N  ND2   . ASN   A 1 123 ? 8.047   21.809  -12.199 1.000 52.768  0 123 ASN   A ND2   1 ? 
ATOM   991  N  N     . LEU   A 1 124 ? 5.360   24.094  -9.542  1.000 52.802  0 124 LEU   A N     1 ? 
ATOM   992  C  CA    . LEU   A 1 124 ? 4.316   23.852  -8.562  1.000 47.341  0 124 LEU   A CA    1 ? 
ATOM   993  C  C     . LEU   A 1 124 ? 4.801   22.914  -7.462  1.000 50.986  0 124 LEU   A C     1 ? 
ATOM   994  O  O     . LEU   A 1 124 ? 4.488   23.150  -6.299  1.000 49.069  0 124 LEU   A O     1 ? 
ATOM   995  C  CB    . LEU   A 1 124 ? 3.089   23.268  -9.262  1.000 50.337  0 124 LEU   A CB    1 ? 
ATOM   996  C  CG    . LEU   A 1 124 ? 1.947   22.850  -8.331  1.000 52.616  0 124 LEU   A CG    1 ? 
ATOM   997  C  CD1   . LEU   A 1 124 ? 1.344   24.091  -7.654  1.000 49.609  0 124 LEU   A CD1   1 ? 
ATOM   998  C  CD2   . LEU   A 1 124 ? 0.876   22.040  -9.039  1.000 55.419  0 124 LEU   A CD2   1 ? 
ATOM   999  N  N     . MET   A 1 125 ? 5.488   21.825  -7.836  1.000 46.598  0 125 MET   A N     1 ? 
ATOM   1000 C  CA    . MET   A 1 125 ? 5.864   20.813  -6.863  1.000 47.154  0 125 MET   A CA    1 ? 
ATOM   1001 C  C     . MET   A 1 125 ? 6.956   21.366  -5.946  1.000 51.669  0 125 MET   A C     1 ? 
ATOM   1002 O  O     . MET   A 1 125 ? 7.020   20.973  -4.789  1.000 52.325  0 125 MET   A O     1 ? 
ATOM   1003 C  CB    . MET   A 1 125 ? 6.341   19.504  -7.496  1.000 47.165  0 125 MET   A CB    1 ? 
ATOM   1004 C  CG    . MET   A 1 125 ? 5.457   18.993  -8.611  1.000 48.777  0 125 MET   A CG    1 ? 
ATOM   1005 S  SD    . MET   A 1 125 ? 3.712   19.022  -8.167  1.000 52.006  0 125 MET   A SD    1 ? 
ATOM   1006 C  CE    . MET   A 1 125 ? 3.673   17.495  -7.226  1.000 50.699  0 125 MET   A CE    1 ? 
ATOM   1007 N  N     . SER   A 1 126 ? 7.781   22.297  -6.437  1.000 52.799  0 126 SER   A N     1 ? 
ATOM   1008 C  CA    . SER   A 1 126 ? 8.743   22.967  -5.582  1.000 47.062  0 126 SER   A CA    1 ? 
ATOM   1009 C  C     . SER   A 1 126 ? 8.015   23.914  -4.620  1.000 52.854  0 126 SER   A C     1 ? 
ATOM   1010 O  O     . SER   A 1 126 ? 8.308   23.966  -3.436  1.000 49.446  0 126 SER   A O     1 ? 
ATOM   1011 C  CB    . SER   A 1 126 ? 9.739   23.699  -6.386  1.000 47.372  0 126 SER   A CB    1 ? 
ATOM   1012 O  OG    . SER   A 1 126 ? 10.544  22.827  -7.154  1.000 51.596  0 126 SER   A OG    1 ? 
ATOM   1013 N  N     . TRP   A 1 127 ? 7.049   24.656  -5.153  1.000 50.549  0 127 TRP   A N     1 ? 
ATOM   1014 C  CA    . TRP   A 1 127 ? 6.207   25.542  -4.375  1.000 54.618  0 127 TRP   A CA    1 ? 
ATOM   1015 C  C     . TRP   A 1 127 ? 5.561   24.770  -3.233  1.000 52.638  0 127 TRP   A C     1 ? 
ATOM   1016 O  O     . TRP   A 1 127 ? 5.537   25.231  -2.097  1.000 47.364  0 127 TRP   A O     1 ? 
ATOM   1017 C  CB    . TRP   A 1 127 ? 5.158   26.159  -5.310  1.000 57.530  0 127 TRP   A CB    1 ? 
ATOM   1018 C  CG    . TRP   A 1 127 ? 4.111   26.991  -4.627  1.000 52.627  0 127 TRP   A CG    1 ? 
ATOM   1019 C  CD1   . TRP   A 1 127 ? 4.158   28.336  -4.419  1.000 60.060  0 127 TRP   A CD1   1 ? 
ATOM   1020 C  CD2   . TRP   A 1 127 ? 2.856   26.550  -4.081  1.000 54.087  0 127 TRP   A CD2   1 ? 
ATOM   1021 N  NE1   . TRP   A 1 127 ? 3.017   28.763  -3.800  1.000 54.873  0 127 TRP   A NE1   1 ? 
ATOM   1022 C  CE2   . TRP   A 1 127 ? 2.205   27.692  -3.569  1.000 55.028  0 127 TRP   A CE2   1 ? 
ATOM   1023 C  CE3   . TRP   A 1 127 ? 2.212   25.318  -3.982  1.000 50.706  0 127 TRP   A CE3   1 ? 
ATOM   1024 C  CZ2   . TRP   A 1 127 ? 0.969   27.626  -2.943  1.000 48.987  0 127 TRP   A CZ2   1 ? 
ATOM   1025 C  CZ3   . TRP   A 1 127 ? 0.970   25.262  -3.394  1.000 47.577  0 127 TRP   A CZ3   1 ? 
ATOM   1026 C  CH2   . TRP   A 1 127 ? 0.363   26.396  -2.881  1.000 52.484  0 127 TRP   A CH2   1 ? 
ATOM   1027 N  N     . GLY   A 1 128 ? 5.079   23.568  -3.552  1.000 48.313  0 128 GLY   A N     1 ? 
ATOM   1028 C  CA    . GLY   A 1 128 ? 4.325   22.761  -2.615  1.000 51.663  0 128 GLY   A CA    1 ? 
ATOM   1029 C  C     . GLY   A 1 128 ? 5.202   22.050  -1.583  1.000 50.740  0 128 GLY   A C     1 ? 
ATOM   1030 O  O     . GLY   A 1 128 ? 4.807   21.964  -0.429  1.000 46.872  0 128 GLY   A O     1 ? 
ATOM   1031 N  N     . VAL   A 1 129 ? 6.347   21.481  -1.975  1.000 49.884  0 129 VAL   A N     1 ? 
ATOM   1032 C  CA    . VAL   A 1 129 ? 7.167   20.783  -0.988  1.000 55.282  0 129 VAL   A CA    1 ? 
ATOM   1033 C  C     . VAL   A 1 129 ? 7.680   21.766  0.055   1.000 43.934  0 129 VAL   A C     1 ? 
ATOM   1034 O  O     . VAL   A 1 129 ? 8.030   21.366  1.151   1.000 50.791  0 129 VAL   A O     1 ? 
ATOM   1035 C  CB    . VAL   A 1 129 ? 8.466   20.075  -1.392  1.000 51.527  0 129 VAL   A CB    1 ? 
ATOM   1036 C  CG1   . VAL   A 1 129 ? 8.392   18.575  -1.330  1.000 52.704  0 129 VAL   A CG1   1 ? 
ATOM   1037 C  CG2   . VAL   A 1 129 ? 9.098   20.694  -2.600  1.000 51.044  0 129 VAL   A CG2   1 ? 
ATOM   1038 N  N     . SER   A 1 130 ? 7.979   22.977  -0.394  1.000 49.897  0 130 SER   A N     1 ? 
ATOM   1039 C  CA    . SER   A 1 130 ? 8.653   23.942  0.439   1.000 49.667  0 130 SER   A CA    1 ? 
ATOM   1040 C  C     . SER   A 1 130 ? 7.735   24.326  1.594   1.000 44.111  0 130 SER   A C     1 ? 
ATOM   1041 O  O     . SER   A 1 130 ? 6.517   24.386  1.454   1.000 48.590  0 130 SER   A O     1 ? 
ATOM   1042 C  CB    . SER   A 1 130 ? 9.045   25.126  -0.376  1.000 50.504  0 130 SER   A CB    1 ? 
ATOM   1043 O  OG    . SER   A 1 130 ? 7.892   25.903  -0.683  1.000 53.241  0 130 SER   A OG    1 ? 
ATOM   1044 N  N     . ASP   A 1 131 ? 8.335   24.564  2.750   1.000 52.303  0 131 ASP   A N     1 ? 
ATOM   1045 C  CA    . ASP   A 1 131 ? 7.603   25.155  3.859   1.000 49.810  0 131 ASP   A CA    1 ? 
ATOM   1046 C  C     . ASP   A 1 131 ? 7.632   26.675  3.760   1.000 44.348  0 131 ASP   A C     1 ? 
ATOM   1047 O  O     . ASP   A 1 131 ? 6.786   27.368  4.325   1.000 53.979  0 131 ASP   A O     1 ? 
ATOM   1048 C  CB    . ASP   A 1 131 ? 8.162   24.634  5.171   1.000 47.679  0 131 ASP   A CB    1 ? 
ATOM   1049 C  CG    . ASP   A 1 131 ? 7.874   23.164  5.391   1.000 48.460  0 131 ASP   A CG    1 ? 
ATOM   1050 O  OD1   . ASP   A 1 131 ? 6.665   22.803  5.306   1.000 51.356  0 131 ASP   A OD1   1 ? 
ATOM   1051 O  OD2   . ASP   A 1 131 ? 8.848   22.410  5.629   1.000 45.510  0 131 ASP   A OD2   1 ? 
ATOM   1052 N  N     . ASN   A 1 132 ? 8.630   27.202  3.058   1.000 43.618  0 132 ASN   A N     1 ? 
ATOM   1053 C  CA    . ASN   A 1 132 ? 8.812   28.644  2.991   1.000 45.353  0 132 ASN   A CA    1 ? 
ATOM   1054 C  C     . ASN   A 1 132 ? 9.830   28.908  1.887   1.000 47.557  0 132 ASN   A C     1 ? 
ATOM   1055 O  O     . ASN   A 1 132 ? 10.633  28.021  1.576   1.000 48.115  0 132 ASN   A O     1 ? 
ATOM   1056 C  CB    . ASN   A 1 132 ? 9.236   29.158  4.369   1.000 44.769  0 132 ASN   A CB    1 ? 
ATOM   1057 C  CG    . ASN   A 1 132 ? 9.345   30.661  4.493   1.000 46.376  0 132 ASN   A CG    1 ? 
ATOM   1058 O  OD1   . ASN   A 1 132 ? 10.088  31.173  5.345   1.000 56.349  0 132 ASN   A OD1   1 ? 
ATOM   1059 N  ND2   . ASN   A 1 132 ? 8.667   31.389  3.640   1.000 47.440  0 132 ASN   A ND2   1 ? 
ATOM   1060 N  N     . VAL   A 1 133 ? 9.808   30.126  1.328   1.000 48.820  0 133 VAL   A N     1 ? 
ATOM   1061 C  CA    . VAL   A 1 133 ? 10.799  30.539  0.358   1.000 45.735  0 133 VAL   A CA    1 ? 
ATOM   1062 C  C     . VAL   A 1 133 ? 11.130  32.024  0.522   1.000 47.902  0 133 VAL   A C     1 ? 
ATOM   1063 O  O     . VAL   A 1 133 ? 10.270  32.872  0.604   1.000 56.870  0 133 VAL   A O     1 ? 
ATOM   1064 C  CB    . VAL   A 1 133 ? 10.439  30.118  -1.084  1.000 55.906  0 133 VAL   A CB    1 ? 
ATOM   1065 C  CG1   . VAL   A 1 133 ? 9.057   29.513  -1.246  1.000 57.600  0 133 VAL   A CG1   1 ? 
ATOM   1066 C  CG2   . VAL   A 1 133 ? 10.756  31.172  -2.126  1.000 57.783  0 133 VAL   A CG2   1 ? 
ATOM   1067 N  N     . ILE   A 1 134 ? 12.437  32.307  0.596   1.000 50.818  0 134 ILE   A N     1 ? 
ATOM   1068 C  CA    . ILE   A 1 134 ? 12.966  33.604  0.955   1.000 47.890  0 134 ILE   A CA    1 ? 
ATOM   1069 C  C     . ILE   A 1 134 ? 13.970  34.048  -0.102  1.000 50.731  0 134 ILE   A C     1 ? 
ATOM   1070 O  O     . ILE   A 1 134 ? 14.370  33.263  -0.948  1.000 50.699  0 134 ILE   A O     1 ? 
ATOM   1071 C  CB    . ILE   A 1 134 ? 13.635  33.529  2.333   1.000 48.492  0 134 ILE   A CB    1 ? 
ATOM   1072 C  CG1   . ILE   A 1 134 ? 14.807  32.548  2.336   1.000 44.889  0 134 ILE   A CG1   1 ? 
ATOM   1073 C  CG2   . ILE   A 1 134 ? 12.592  33.191  3.403   1.000 54.253  0 134 ILE   A CG2   1 ? 
ATOM   1074 C  CD1   . ILE   A 1 134 ? 15.810  32.809  3.430   1.000 44.981  0 134 ILE   A CD1   1 ? 
ATOM   1075 N  N     . LYS   A 1 135 ? 14.426  35.297  -0.010  1.000 54.892  0 135 LYS   A N     1 ? 
ATOM   1076 C  CA    . LYS   A 1 135 ? 15.418  35.797  -0.939  1.000 55.030  0 135 LYS   A CA    1 ? 
ATOM   1077 C  C     . LYS   A 1 135 ? 16.801  35.629  -0.320  1.000 52.132  0 135 LYS   A C     1 ? 
ATOM   1078 O  O     . LYS   A 1 135 ? 16.948  35.538  0.885   1.000 55.439  0 135 LYS   A O     1 ? 
ATOM   1079 C  CB    . LYS   A 1 135 ? 15.043  37.199  -1.432  1.000 59.133  0 135 LYS   A CB    1 ? 
ATOM   1080 C  CG    . LYS   A 1 135 ? 14.885  38.289  -0.412  1.000 69.058  0 135 LYS   A CG    1 ? 
ATOM   1081 C  CD    . LYS   A 1 135 ? 14.351  39.568  -1.051  1.000 68.959  0 135 LYS   A CD    1 ? 
ATOM   1082 C  CE    . LYS   A 1 135 ? 12.906  39.559  -1.450  1.000 91.323  0 135 LYS   A CE    1 ? 
ATOM   1083 N  NZ    . LYS   A 1 135 ? 12.348  40.914  -1.345  1.000 97.496  0 135 LYS   A NZ    1 ? 
ATOM   1084 N  N     . MET   A 1 136 ? 17.820  35.560  -1.174  1.000 47.415  0 136 MET   A N     1 ? 
ATOM   1085 C  CA    . MET   A 1 136 ? 19.181  35.382  -0.723  1.000 52.251  0 136 MET   A CA    1 ? 
ATOM   1086 C  C     . MET   A 1 136 ? 19.542  36.366  0.389   1.000 58.466  0 136 MET   A C     1 ? 
ATOM   1087 O  O     . MET   A 1 136 ? 20.242  35.995  1.338   1.000 59.073  0 136 MET   A O     1 ? 
ATOM   1088 C  CB    . MET   A 1 136 ? 20.154  35.531  -1.893  1.000 53.869  0 136 MET   A CB    1 ? 
ATOM   1089 C  CG    . MET   A 1 136 ? 21.590  35.199  -1.538  1.000 54.146  0 136 MET   A CG    1 ? 
ATOM   1090 S  SD    . MET   A 1 136 ? 21.761  33.434  -1.199  1.000 53.717  0 136 MET   A SD    1 ? 
ATOM   1091 C  CE    . MET   A 1 136 ? 21.429  32.795  -2.857  1.000 51.679  0 136 MET   A CE    1 ? 
ATOM   1092 N  N     . SER   A 1 137 ? 19.066  37.612  0.284   1.000 56.933  0 137 SER   A N     1 ? 
ATOM   1093 C  CA    . SER   A 1 137 ? 19.498  38.655  1.196   1.000 57.681  0 137 SER   A CA    1 ? 
ATOM   1094 C  C     . SER   A 1 137 ? 18.831  38.507  2.562   1.000 62.027  0 137 SER   A C     1 ? 
ATOM   1095 O  O     . SER   A 1 137 ? 19.244  39.182  3.508   1.000 66.989  0 137 SER   A O     1 ? 
ATOM   1096 C  CB    . SER   A 1 137 ? 19.286  40.034  0.618   1.000 57.422  0 137 SER   A CB    1 ? 
ATOM   1097 O  OG    . SER   A 1 137 ? 17.903  40.344  0.591   1.000 57.968  0 137 SER   A OG    1 ? 
ATOM   1098 N  N     . GLN   A 1 138 ? 17.846  37.606  2.676   1.000 59.686  0 138 GLN   A N     1 ? 
ATOM   1099 C  CA    . GLN   A 1 138 ? 17.219  37.312  3.955   1.000 57.310  0 138 GLN   A CA    1 ? 
ATOM   1100 C  C     . GLN   A 1 138 ? 17.928  36.174  4.698   1.000 56.799  0 138 GLN   A C     1 ? 
ATOM   1101 O  O     . GLN   A 1 138 ? 17.688  35.983  5.885   1.000 57.182  0 138 GLN   A O     1 ? 
ATOM   1102 C  CB    . GLN   A 1 138 ? 15.740  36.958  3.793   1.000 58.537  0 138 GLN   A CB    1 ? 
ATOM   1103 C  CG    . GLN   A 1 138 ? 14.825  38.134  3.454   1.000 53.373  0 138 GLN   A CG    1 ? 
ATOM   1104 C  CD    . GLN   A 1 138 ? 13.412  37.689  3.127   1.000 51.729  0 138 GLN   A CD    1 ? 
ATOM   1105 O  OE1   . GLN   A 1 138 ? 13.155  37.016  2.130   1.000 46.629  0 138 GLN   A OE1   1 ? 
ATOM   1106 N  NE2   . GLN   A 1 138 ? 12.454  38.019  3.967   1.000 55.548  0 138 GLN   A NE2   1 ? 
ATOM   1107 N  N     . LEU   A 1 139 ? 18.839  35.454  4.051   1.000 56.711  0 139 LEU   A N     1 ? 
ATOM   1108 C  CA    . LEU   A 1 139 ? 19.302  34.187  4.600   1.000 52.237  0 139 LEU   A CA    1 ? 
ATOM   1109 C  C     . LEU   A 1 139 ? 20.187  34.404  5.835   1.000 51.156  0 139 LEU   A C     1 ? 
ATOM   1110 O  O     . LEU   A 1 139 ? 20.096  33.645  6.802   1.000 50.293  0 139 LEU   A O     1 ? 
ATOM   1111 C  CB    . LEU   A 1 139 ? 20.007  33.380  3.514   1.000 53.611  0 139 LEU   A CB    1 ? 
ATOM   1112 C  CG    . LEU   A 1 139 ? 20.548  32.002  3.917   1.000 50.053  0 139 LEU   A CG    1 ? 
ATOM   1113 C  CD1   . LEU   A 1 139 ? 19.445  31.148  4.486   1.000 53.047  0 139 LEU   A CD1   1 ? 
ATOM   1114 C  CD2   . LEU   A 1 139 ? 21.174  31.299  2.753   1.000 50.518  0 139 LEU   A CD2   1 ? 
ATOM   1115 N  N     . LYS   A 1 140 ? 21.018  35.451  5.836   1.000 51.709  0 140 LYS   A N     1 ? 
ATOM   1116 C  CA    . LYS   A 1 140 ? 21.912  35.750  6.959   1.000 56.350  0 140 LYS   A CA    1 ? 
ATOM   1117 C  C     . LYS   A 1 140 ? 21.153  36.036  8.255   1.000 48.834  0 140 LYS   A C     1 ? 
ATOM   1118 O  O     . LYS   A 1 140 ? 21.702  35.825  9.320   1.000 47.387  0 140 LYS   A O     1 ? 
ATOM   1119 C  CB    . LYS   A 1 140 ? 22.871  36.922  6.681   1.000 72.172  0 140 LYS   A CB    1 ? 
ATOM   1120 C  CG    . LYS   A 1 140 ? 22.240  38.323  6.523   1.000 74.731  0 140 LYS   A CG    1 ? 
ATOM   1121 C  CD    . LYS   A 1 140 ? 23.078  39.334  5.734   1.000 81.247  0 140 LYS   A CD    1 ? 
ATOM   1122 C  CE    . LYS   A 1 140 ? 24.055  40.083  6.583   1.000 96.134  0 140 LYS   A CE    1 ? 
ATOM   1123 N  NZ    . LYS   A 1 140 ? 23.377  41.084  7.415   1.000 101.001 0 140 LYS   A NZ    1 ? 
ATOM   1124 N  N     . ASP   A 1 141 ? 19.883  36.441  8.182   1.000 49.668  0 141 ASP   A N     1 ? 
ATOM   1125 C  CA    . ASP   A 1 141 ? 19.154  36.888  9.359   1.000 58.195  0 141 ASP   A CA    1 ? 
ATOM   1126 C  C     . ASP   A 1 141 ? 17.990  35.973  9.694   1.000 56.083  0 141 ASP   A C     1 ? 
ATOM   1127 O  O     . ASP   A 1 141 ? 17.274  36.194  10.675  1.000 55.922  0 141 ASP   A O     1 ? 
ATOM   1128 C  CB    . ASP   A 1 141 ? 18.619  38.299  9.146   1.000 63.334  0 141 ASP   A CB    1 ? 
ATOM   1129 C  CG    . ASP   A 1 141 ? 19.704  39.360  8.999   1.000 67.582  0 141 ASP   A CG    1 ? 
ATOM   1130 O  OD1   . ASP   A 1 141 ? 20.696  39.300  9.769   1.000 69.741  0 141 ASP   A OD1   1 ? 
ATOM   1131 O  OD2   . ASP   A 1 141 ? 19.532  40.231  8.128   1.000 67.183  0 141 ASP   A OD2   1 ? 
ATOM   1132 N  N     . PHE   A 1 142 ? 17.776  34.967  8.853   1.000 54.609  0 142 PHE   A N     1 ? 
ATOM   1133 C  CA    . PHE   A 1 142 ? 16.670  34.054  9.073   1.000 55.017  0 142 PHE   A CA    1 ? 
ATOM   1134 C  C     . PHE   A 1 142 ? 16.843  33.354  10.430  1.000 49.802  0 142 PHE   A C     1 ? 
ATOM   1135 O  O     . PHE   A 1 142 ? 17.918  32.822  10.732  1.000 48.006  0 142 PHE   A O     1 ? 
ATOM   1136 C  CB    . PHE   A 1 142 ? 16.619  33.073  7.894   1.000 47.737  0 142 PHE   A CB    1 ? 
ATOM   1137 C  CG    . PHE   A 1 142 ? 15.359  32.232  7.926   1.000 46.562  0 142 PHE   A CG    1 ? 
ATOM   1138 C  CD1   . PHE   A 1 142 ? 15.324  31.060  8.669   1.000 45.139  0 142 PHE   A CD1   1 ? 
ATOM   1139 C  CD2   . PHE   A 1 142 ? 14.196  32.645  7.286   1.000 49.211  0 142 PHE   A CD2   1 ? 
ATOM   1140 C  CE1   . PHE   A 1 142 ? 14.183  30.275  8.696   1.000 44.602  0 142 PHE   A CE1   1 ? 
ATOM   1141 C  CE2   . PHE   A 1 142 ? 13.057  31.857  7.314   1.000 45.918  0 142 PHE   A CE2   1 ? 
ATOM   1142 C  CZ    . PHE   A 1 142 ? 13.035  30.694  8.039   1.000 50.651  0 142 PHE   A CZ    1 ? 
ATOM   1143 N  N     . ASN   A 1 143 ? 15.771  33.336  11.225  1.000 48.475  0 143 ASN   A N     1 ? 
ATOM   1144 C  CA    . ASN   A 1 143 ? 15.788  32.670  12.513  1.000 48.969  0 143 ASN   A CA    1 ? 
ATOM   1145 C  C     . ASN   A 1 143 ? 15.382  31.209  12.364  1.000 46.678  0 143 ASN   A C     1 ? 
ATOM   1146 O  O     . ASN   A 1 143 ? 14.206  30.883  12.312  1.000 47.105  0 143 ASN   A O     1 ? 
ATOM   1147 C  CB    . ASN   A 1 143 ? 14.871  33.327  13.522  1.000 48.037  0 143 ASN   A CB    1 ? 
ATOM   1148 C  CG    . ASN   A 1 143 ? 15.081  32.749  14.900  1.000 52.901  0 143 ASN   A CG    1 ? 
ATOM   1149 O  OD1   . ASN   A 1 143 ? 15.817  31.772  15.057  1.000 51.300  0 143 ASN   A OD1   1 ? 
ATOM   1150 N  ND2   . ASN   A 1 143 ? 14.392  33.285  15.898  1.000 54.849  0 143 ASN   A ND2   1 ? 
ATOM   1151 N  N     . PHE   A 1 144 ? 16.388  30.336  12.359  1.000 54.140  0 144 PHE   A N     1 ? 
ATOM   1152 C  CA    . PHE   A 1 144 ? 16.164  28.921  12.132  1.000 52.138  0 144 PHE   A CA    1 ? 
ATOM   1153 C  C     . PHE   A 1 144 ? 15.625  28.243  13.383  1.000 48.804  0 144 PHE   A C     1 ? 
ATOM   1154 O  O     . PHE   A 1 144 ? 15.202  27.107  13.295  1.000 53.344  0 144 PHE   A O     1 ? 
ATOM   1155 C  CB    . PHE   A 1 144 ? 17.468  28.287  11.656  1.000 49.267  0 144 PHE   A CB    1 ? 
ATOM   1156 C  CG    . PHE   A 1 144 ? 17.737  28.590  10.198  1.000 48.072  0 144 PHE   A CG    1 ? 
ATOM   1157 C  CD1   . PHE   A 1 144 ? 17.076  27.877  9.202   1.000 48.793  0 144 PHE   A CD1   1 ? 
ATOM   1158 C  CD2   . PHE   A 1 144 ? 18.626  29.584  9.829   1.000 46.065  0 144 PHE   A CD2   1 ? 
ATOM   1159 C  CE1   . PHE   A 1 144 ? 17.325  28.129  7.875   1.000 50.318  0 144 PHE   A CE1   1 ? 
ATOM   1160 C  CE2   . PHE   A 1 144 ? 18.872  29.837  8.495   1.000 50.179  0 144 PHE   A CE2   1 ? 
ATOM   1161 C  CZ    . PHE   A 1 144 ? 18.228  29.107  7.521   1.000 53.854  0 144 PHE   A CZ    1 ? 
ATOM   1162 N  N     . ASN   A 1 145 ? 15.586  28.948  14.519  1.000 51.018  0 145 ASN   A N     1 ? 
ATOM   1163 C  CA    . ASN   A 1 145 ? 14.997  28.369  15.722  1.000 52.462  0 145 ASN   A CA    1 ? 
ATOM   1164 C  C     . ASN   A 1 145 ? 13.473  28.478  15.721  1.000 46.311  0 145 ASN   A C     1 ? 
ATOM   1165 O  O     . ASN   A 1 145 ? 12.819  27.737  16.470  1.000 45.829  0 145 ASN   A O     1 ? 
ATOM   1166 C  CB    . ASN   A 1 145 ? 15.544  28.989  17.009  1.000 54.072  0 145 ASN   A CB    1 ? 
ATOM   1167 C  CG    . ASN   A 1 145 ? 17.011  28.705  17.162  1.000 49.016  0 145 ASN   A CG    1 ? 
ATOM   1168 O  OD1   . ASN   A 1 145 ? 17.426  27.541  17.168  1.000 53.396  0 145 ASN   A OD1   1 ? 
ATOM   1169 N  ND2   . ASN   A 1 145 ? 17.802  29.754  17.228  1.000 56.651  0 145 ASN   A ND2   1 ? 
ATOM   1170 N  N     . LYS   A 1 146 ? 12.919  29.390  14.909  1.000 54.395  0 146 LYS   A N     1 ? 
ATOM   1171 C  CA    . LYS   A 1 146 ? 11.473  29.603  14.867  1.000 60.886  0 146 LYS   A CA    1 ? 
ATOM   1172 C  C     . LYS   A 1 146 ? 10.985  29.553  13.412  1.000 62.020  0 146 LYS   A C     1 ? 
ATOM   1173 O  O     . LYS   A 1 146 ? 10.383  30.476  12.872  1.000 59.382  0 146 LYS   A O     1 ? 
ATOM   1174 C  CB    . LYS   A 1 146 ? 11.117  30.917  15.574  1.000 66.261  0 146 LYS   A CB    1 ? 
ATOM   1175 C  CG    . LYS   A 1 146 ? 11.794  31.222  16.914  1.000 73.087  0 146 LYS   A CG    1 ? 
ATOM   1176 C  CD    . LYS   A 1 146 ? 10.927  31.933  17.954  1.000 78.893  0 146 LYS   A CD    1 ? 
ATOM   1177 C  CE    . LYS   A 1 146 ? 9.886   30.926  18.395  1.000 88.470  0 146 LYS   A CE    1 ? 
ATOM   1178 N  NZ    . LYS   A 1 146 ? 8.693   31.467  19.038  1.000 73.117  0 146 LYS   A NZ    1 ? 
ATOM   1179 N  N     . PRO   A 1 147 ? 11.231  28.446  12.696  1.000 57.700  0 147 PRO   A N     1 ? 
ATOM   1180 C  CA    . PRO   A 1 147 ? 10.857  28.374  11.288  1.000 54.175  0 147 PRO   A CA    1 ? 
ATOM   1181 C  C     . PRO   A 1 147 ? 9.343   28.225  11.156  1.000 48.923  0 147 PRO   A C     1 ? 
ATOM   1182 O  O     . PRO   A 1 147 ? 8.743   27.404  11.858  1.000 46.576  0 147 PRO   A O     1 ? 
ATOM   1183 C  CB    . PRO   A 1 147 ? 11.624  27.129  10.848  1.000 50.800  0 147 PRO   A CB    1 ? 
ATOM   1184 C  CG    . PRO   A 1 147 ? 11.589  26.251  12.074  1.000 51.321  0 147 PRO   A CG    1 ? 
ATOM   1185 C  CD    . PRO   A 1 147 ? 11.788  27.201  13.229  1.000 51.465  0 147 PRO   A CD    1 ? 
ATOM   1186 N  N     . ARG   A 1 148 ? 8.741   29.005  10.251  1.000 54.497  0 148 ARG   A N     1 ? 
ATOM   1187 C  CA    . ARG   A 1 148 ? 7.299   28.985  10.044  1.000 54.655  0 148 ARG   A CA    1 ? 
ATOM   1188 C  C     . ARG   A 1 148 ? 6.971   28.730  8.570   1.000 50.649  0 148 ARG   A C     1 ? 
ATOM   1189 O  O     . ARG   A 1 148 ? 7.797   28.897  7.668   1.000 44.647  0 148 ARG   A O     1 ? 
ATOM   1190 C  CB    . ARG   A 1 148 ? 6.649   30.303  10.475  1.000 64.741  0 148 ARG   A CB    1 ? 
ATOM   1191 C  CG    . ARG   A 1 148 ? 6.765   30.697  11.952  1.000 68.237  0 148 ARG   A CG    1 ? 
ATOM   1192 C  CD    . ARG   A 1 148 ? 6.307   32.167  12.188  1.000 85.716  0 148 ARG   A CD    1 ? 
ATOM   1193 N  NE    . ARG   A 1 148 ? 4.918   32.544  12.521  1.000 80.950  0 148 ARG   A NE    1 ? 
ATOM   1194 C  CZ    . ARG   A 1 148 ? 3.842   32.625  11.738  1.000 79.065  0 148 ARG   A CZ    1 ? 
ATOM   1195 N  NH1   . ARG   A 1 148 ? 3.851   32.175  10.493  1.000 91.571  0 148 ARG   A NH1   1 ? 
ATOM   1196 N  NH2   . ARG   A 1 148 ? 2.728   33.148  12.218  1.000 80.230  0 148 ARG   A NH2   1 ? 
ATOM   1197 N  N     . PHE   A 1 149 ? 5.742   28.256  8.355   1.000 49.505  0 149 PHE   A N     1 ? 
ATOM   1198 C  CA    . PHE   A 1 149 ? 5.167   28.077  7.043   1.000 48.247  0 149 PHE   A CA    1 ? 
ATOM   1199 C  C     . PHE   A 1 149 ? 4.793   29.431  6.444   1.000 58.186  0 149 PHE   A C     1 ? 
ATOM   1200 O  O     . PHE   A 1 149 ? 4.114   30.221  7.088   1.000 55.386  0 149 PHE   A O     1 ? 
ATOM   1201 C  CB    . PHE   A 1 149 ? 3.894   27.243  7.101   1.000 49.371  0 149 PHE   A CB    1 ? 
ATOM   1202 C  CG    . PHE   A 1 149 ? 3.293   27.083  5.710   1.000 52.589  0 149 PHE   A CG    1 ? 
ATOM   1203 C  CD1   . PHE   A 1 149 ? 3.726   26.064  4.876   1.000 56.482  0 149 PHE   A CD1   1 ? 
ATOM   1204 C  CD2   . PHE   A 1 149 ? 2.384   28.002  5.207   1.000 52.971  0 149 PHE   A CD2   1 ? 
ATOM   1205 C  CE1   . PHE   A 1 149 ? 3.258   25.963  3.581   1.000 49.414  0 149 PHE   A CE1   1 ? 
ATOM   1206 C  CE2   . PHE   A 1 149 ? 1.875   27.863  3.930   1.000 55.836  0 149 PHE   A CE2   1 ? 
ATOM   1207 C  CZ    . PHE   A 1 149 ? 2.312   26.837  3.126   1.000 53.770  0 149 PHE   A CZ    1 ? 
ATOM   1208 N  N     . ASP   A 1 150 ? 5.196   29.683  5.193   1.000 57.737  0 150 ASP   A N     1 ? 
ATOM   1209 C  CA    . ASP   A 1 150 ? 4.706   30.849  4.484   1.000 56.265  0 150 ASP   A CA    1 ? 
ATOM   1210 C  C     . ASP   A 1 150 ? 4.657   30.533  2.996   1.000 53.631  0 150 ASP   A C     1 ? 
ATOM   1211 O  O     . ASP   A 1 150 ? 5.334   29.621  2.552   1.000 48.926  0 150 ASP   A O     1 ? 
ATOM   1212 C  CB    . ASP   A 1 150 ? 5.563   32.063  4.777   1.000 58.750  0 150 ASP   A CB    1 ? 
ATOM   1213 C  CG    . ASP   A 1 150 ? 4.910   33.424  4.585   1.000 67.157  0 150 ASP   A CG    1 ? 
ATOM   1214 O  OD1   . ASP   A 1 150 ? 3.741   33.491  4.152   1.000 56.484  0 150 ASP   A OD1   1 ? 
ATOM   1215 O  OD2   . ASP   A 1 150 ? 5.599   34.414  4.870   1.000 78.232  0 150 ASP   A OD2   1 ? 
ATOM   1216 N  N     . PHE   A 1 151 ? 3.863   31.305  2.249   1.000 58.973  0 151 PHE   A N     1 ? 
ATOM   1217 C  CA    . PHE   A 1 151 ? 3.749   31.096  0.813   1.000 55.924  0 151 PHE   A CA    1 ? 
ATOM   1218 C  C     . PHE   A 1 151 ? 4.733   31.985  0.067   1.000 56.225  0 151 PHE   A C     1 ? 
ATOM   1219 O  O     . PHE   A 1 151 ? 4.980   33.129  0.479   1.000 54.070  0 151 PHE   A O     1 ? 
ATOM   1220 C  CB    . PHE   A 1 151 ? 2.372   31.511  0.306   1.000 56.090  0 151 PHE   A CB    1 ? 
ATOM   1221 C  CG    . PHE   A 1 151 ? 1.219   30.628  0.746   1.000 48.038  0 151 PHE   A CG    1 ? 
ATOM   1222 C  CD1   . PHE   A 1 151 ? 1.025   29.373  0.186   1.000 55.044  0 151 PHE   A CD1   1 ? 
ATOM   1223 C  CD2   . PHE   A 1 151 ? 0.262   31.102  1.625   1.000 44.401  0 151 PHE   A CD2   1 ? 
ATOM   1224 C  CE1   . PHE   A 1 151 ? -0.062  28.592  0.568   1.000 55.367  0 151 PHE   A CE1   1 ? 
ATOM   1225 C  CE2   . PHE   A 1 151 ? -0.847  30.330  1.951   1.000 48.844  0 151 PHE   A CE2   1 ? 
ATOM   1226 C  CZ    . PHE   A 1 151 ? -0.997  29.079  1.447   1.000 43.255  0 151 PHE   A CZ    1 ? 
ATOM   1227 N  N     . TYR   A 1 152 ? 5.290   31.448  -1.028  1.000 58.165  0 152 TYR   A N     1 ? 
ATOM   1228 C  CA    . TYR   A 1 152 ? 6.120   32.245  -1.926  1.000 60.818  0 152 TYR   A CA    1 ? 
ATOM   1229 C  C     . TYR   A 1 152 ? 5.319   33.465  -2.404  1.000 57.515  0 152 TYR   A C     1 ? 
ATOM   1230 O  O     . TYR   A 1 152 ? 4.159   33.332  -2.768  1.000 59.055  0 152 TYR   A O     1 ? 
ATOM   1231 C  CB    . TYR   A 1 152 ? 6.537   31.356  -3.094  1.000 52.092  0 152 TYR   A CB    1 ? 
ATOM   1232 C  CG    . TYR   A 1 152 ? 7.445   31.936  -4.175  1.000 54.523  0 152 TYR   A CG    1 ? 
ATOM   1233 C  CD1   . TYR   A 1 152 ? 8.541   32.736  -3.887  1.000 53.373  0 152 TYR   A CD1   1 ? 
ATOM   1234 C  CD2   . TYR   A 1 152 ? 7.222   31.611  -5.508  1.000 52.421  0 152 TYR   A CD2   1 ? 
ATOM   1235 C  CE1   . TYR   A 1 152 ? 9.401   33.170  -4.884  1.000 52.920  0 152 TYR   A CE1   1 ? 
ATOM   1236 C  CE2   . TYR   A 1 152 ? 8.062   32.046  -6.511  1.000 54.195  0 152 TYR   A CE2   1 ? 
ATOM   1237 C  CZ    . TYR   A 1 152 ? 9.133   32.858  -6.203  1.000 53.895  0 152 TYR   A CZ    1 ? 
ATOM   1238 O  OH    . TYR   A 1 152 ? 9.907   33.303  -7.234  1.000 51.016  0 152 TYR   A OH    1 ? 
ATOM   1239 N  N     . GLU   A 1 153 ? 5.949   34.640  -2.353  1.000 57.463  0 153 GLU   A N     1 ? 
ATOM   1240 C  CA    . GLU   A 1 153 ? 5.426   35.863  -2.942  1.000 69.377  0 153 GLU   A CA    1 ? 
ATOM   1241 C  C     . GLU   A 1 153 ? 5.930   35.915  -4.385  1.000 64.594  0 153 GLU   A C     1 ? 
ATOM   1242 O  O     . GLU   A 1 153 ? 6.937   36.575  -4.677  1.000 62.109  0 153 GLU   A O     1 ? 
ATOM   1243 C  CB    . GLU   A 1 153 ? 5.896   37.014  -2.034  1.000 73.625  0 153 GLU   A CB    1 ? 
ATOM   1244 C  CG    . GLU   A 1 153 ? 5.155   38.340  -2.202  1.000 76.188  0 153 GLU   A CG    1 ? 
ATOM   1245 C  CD    . GLU   A 1 153 ? 3.689   38.323  -1.770  1.000 85.593  0 153 GLU   A CD    1 ? 
ATOM   1246 O  OE1   . GLU   A 1 153 ? 3.170   37.275  -1.299  1.000 72.071  0 153 GLU   A OE1   1 ? 
ATOM   1247 O  OE2   . GLU   A 1 153 ? 3.051   39.388  -1.934  1.000 74.196  0 153 GLU   A OE2   1 ? 
ATOM   1248 N  N     . GLY   A 1 154 ? 5.281   35.116  -5.246  1.000 62.260  0 154 GLY   A N     1 ? 
ATOM   1249 C  CA    . GLY   A 1 154 ? 5.735   34.880  -6.609  1.000 55.679  0 154 GLY   A CA    1 ? 
ATOM   1250 C  C     . GLY   A 1 154 ? 4.853   33.848  -7.308  1.000 56.792  0 154 GLY   A C     1 ? 
ATOM   1251 O  O     . GLY   A 1 154 ? 3.938   33.292  -6.708  1.000 58.799  0 154 GLY   A O     1 ? 
ATOM   1252 N  N     . ALA   A 1 155 ? 5.106   33.593  -8.592  1.000 60.178  0 155 ALA   A N     1 ? 
ATOM   1253 C  CA    . ALA   A 1 155 ? 4.227   32.717  -9.359  1.000 67.486  0 155 ALA   A CA    1 ? 
ATOM   1254 C  C     . ALA   A 1 155 ? 4.660   31.249  -9.254  1.000 56.907  0 155 ALA   A C     1 ? 
ATOM   1255 O  O     . ALA   A 1 155 ? 5.787   30.940  -8.873  1.000 62.660  0 155 ALA   A O     1 ? 
ATOM   1256 C  CB    . ALA   A 1 155 ? 4.231   33.159  -10.808 1.000 79.779  0 155 ALA   A CB    1 ? 
ATOM   1257 N  N     . VAL   A 1 156 ? 3.753   30.347  -9.634  1.000 54.075  0 156 VAL   A N     1 ? 
ATOM   1258 C  CA    . VAL   A 1 156 ? 4.116   28.999  -10.035 1.000 59.673  0 156 VAL   A CA    1 ? 
ATOM   1259 C  C     . VAL   A 1 156 ? 3.783   28.780  -11.509 1.000 59.041  0 156 VAL   A C     1 ? 
ATOM   1260 O  O     . VAL   A 1 156 ? 3.053   29.551  -12.108 1.000 63.339  0 156 VAL   A O     1 ? 
ATOM   1261 C  CB    . VAL   A 1 156 ? 3.386   27.928  -9.219  1.000 64.947  0 156 VAL   A CB    1 ? 
ATOM   1262 C  CG1   . VAL   A 1 156 ? 3.492   28.210  -7.732  1.000 68.959  0 156 VAL   A CG1   1 ? 
ATOM   1263 C  CG2   . VAL   A 1 156 ? 1.943   27.812  -9.673  1.000 68.390  0 156 VAL   A CG2   1 ? 
ATOM   1264 N  N     . TYR   A 1 157 ? 4.345   27.716  -12.071 1.000 62.017  0 157 TYR   A N     1 ? 
ATOM   1265 C  CA    . TYR   A 1 157 ? 3.863   27.125  -13.311 1.000 68.264  0 157 TYR   A CA    1 ? 
ATOM   1266 C  C     . TYR   A 1 157 ? 3.601   25.601  -13.072 1.000 77.303  0 157 TYR   A C     1 ? 
ATOM   1267 O  O     . TYR   A 1 157 ? 2.703   25.066  -13.778 1.000 81.985  0 157 TYR   A O     1 ? 
ATOM   1268 C  CB    . TYR   A 1 157 ? 4.896   27.426  -14.396 1.000 56.754  0 157 TYR   A CB    1 ? 
ATOM   1269 C  CG    . TYR   A 1 157 ? 6.182   26.627  -14.229 1.000 58.681  0 157 TYR   A CG    1 ? 
ATOM   1270 C  CD1   . TYR   A 1 157 ? 6.287   25.318  -14.700 1.000 61.794  0 157 TYR   A CD1   1 ? 
ATOM   1271 C  CD2   . TYR   A 1 157 ? 7.296   27.178  -13.593 1.000 67.941  0 157 TYR   A CD2   1 ? 
ATOM   1272 C  CE1   . TYR   A 1 157 ? 7.457   24.586  -14.540 1.000 59.287  0 157 TYR   A CE1   1 ? 
ATOM   1273 C  CE2   . TYR   A 1 157 ? 8.472   26.459  -13.431 1.000 57.630  0 157 TYR   A CE2   1 ? 
ATOM   1274 C  CZ    . TYR   A 1 157 ? 8.553   25.158  -13.906 1.000 61.854  0 157 TYR   A CZ    1 ? 
ATOM   1275 O  OH    . TYR   A 1 157 ? 9.703   24.418  -13.730 1.000 56.184  0 157 TYR   A OH    1 ? 
ATOM   1276 O  OXT   . TYR   A 1 157 ? 4.276   24.974  -12.205 1.000 72.517  0 157 TYR   A OXT   1 ? 
ATOM   1277 N  N     . MET   B 1 1   ? -4.340  -11.891 -15.760 1.000 94.985  0 1   MET   B N     1 ? 
ATOM   1278 C  CA    . MET   B 1 1   ? -3.232  -11.363 -14.911 1.000 103.742 0 1   MET   B CA    1 ? 
ATOM   1279 C  C     . MET   B 1 1   ? -3.789  -10.397 -13.844 1.000 97.385  0 1   MET   B C     1 ? 
ATOM   1280 O  O     . MET   B 1 1   ? -4.823  -9.754  -14.028 1.000 82.617  0 1   MET   B O     1 ? 
ATOM   1281 C  CB    . MET   B 1 1   ? -2.148  -10.684 -15.771 1.000 86.196  0 1   MET   B CB    1 ? 
ATOM   1282 N  N     . PRO   B 1 2   ? -3.160  -10.277 -12.650 1.000 90.570  0 2   PRO   B N     1 ? 
ATOM   1283 C  CA    . PRO   B 1 2   ? -3.381  -9.111  -11.786 1.000 84.551  0 2   PRO   B CA    1 ? 
ATOM   1284 C  C     . PRO   B 1 2   ? -2.869  -7.850  -12.481 1.000 75.346  0 2   PRO   B C     1 ? 
ATOM   1285 O  O     . PRO   B 1 2   ? -1.932  -7.905  -13.278 1.000 68.228  0 2   PRO   B O     1 ? 
ATOM   1286 C  CB    . PRO   B 1 2   ? -2.599  -9.405  -10.483 1.000 83.559  0 2   PRO   B CB    1 ? 
ATOM   1287 C  CG    . PRO   B 1 2   ? -2.184  -10.867 -10.582 1.000 87.120  0 2   PRO   B CG    1 ? 
ATOM   1288 C  CD    . PRO   B 1 2   ? -2.250  -11.265 -12.050 1.000 88.324  0 2   PRO   B CD    1 ? 
ATOM   1289 N  N     . LYS   B 1 3   ? -3.487  -6.709  -12.169 1.000 77.389  0 3   LYS   B N     1 ? 
ATOM   1290 C  CA    . LYS   B 1 3   ? -3.090  -5.431  -12.748 1.000 77.514  0 3   LYS   B CA    1 ? 
ATOM   1291 C  C     . LYS   B 1 3   ? -2.752  -4.424  -11.644 1.000 68.551  0 3   LYS   B C     1 ? 
ATOM   1292 O  O     . LYS   B 1 3   ? -3.354  -4.440  -10.580 1.000 68.119  0 3   LYS   B O     1 ? 
ATOM   1293 C  CB    . LYS   B 1 3   ? -4.239  -4.881  -13.593 1.000 86.910  0 3   LYS   B CB    1 ? 
ATOM   1294 C  CG    . LYS   B 1 3   ? -4.803  -5.727  -14.728 1.000 96.279  0 3   LYS   B CG    1 ? 
ATOM   1295 C  CD    . LYS   B 1 3   ? -6.166  -5.195  -15.182 1.000 99.955  0 3   LYS   B CD    1 ? 
ATOM   1296 C  CE    . LYS   B 1 3   ? -6.849  -5.954  -16.292 1.000 104.608 0 3   LYS   B CE    1 ? 
ATOM   1297 N  NZ    . LYS   B 1 3   ? -6.137  -5.865  -17.570 1.000 99.403  0 3   LYS   B NZ    1 ? 
ATOM   1298 N  N     . LYS   B 1 4   ? -1.798  -3.530  -11.915 1.000 71.270  0 4   LYS   B N     1 ? 
ATOM   1299 C  CA    . LYS   B 1 4   ? -1.411  -2.481  -10.985 1.000 60.824  0 4   LYS   B CA    1 ? 
ATOM   1300 C  C     . LYS   B 1 4   ? -1.717  -1.123  -11.607 1.000 61.954  0 4   LYS   B C     1 ? 
ATOM   1301 O  O     . LYS   B 1 4   ? -1.710  -0.993  -12.827 1.000 58.309  0 4   LYS   B O     1 ? 
ATOM   1302 C  CB    . LYS   B 1 4   ? 0.100   -2.538  -10.769 1.000 62.030  0 4   LYS   B CB    1 ? 
ATOM   1303 C  CG    . LYS   B 1 4   ? 0.640   -3.819  -10.141 1.000 63.755  0 4   LYS   B CG    1 ? 
ATOM   1304 C  CD    . LYS   B 1 4   ? 0.293   -4.084  -8.677  1.000 67.043  0 4   LYS   B CD    1 ? 
ATOM   1305 C  CE    . LYS   B 1 4   ? 1.089   -5.272  -8.101  1.000 76.825  0 4   LYS   B CE    1 ? 
ATOM   1306 N  NZ    . LYS   B 1 4   ? 2.577   -5.256  -8.172  1.000 75.211  0 4   LYS   B NZ    1 ? 
ATOM   1307 N  N     . THR   B 1 5   ? -1.949  -0.102  -10.774 1.000 59.743  0 5   THR   B N     1 ? 
ATOM   1308 C  CA    . THR   B 1 5   ? -2.164  1.253   -11.264 1.000 54.126  0 5   THR   B CA    1 ? 
ATOM   1309 C  C     . THR   B 1 5   ? -0.868  2.036   -11.112 1.000 61.445  0 5   THR   B C     1 ? 
ATOM   1310 O  O     . THR   B 1 5   ? -0.005  1.674   -10.305 1.000 55.834  0 5   THR   B O     1 ? 
ATOM   1311 C  CB    . THR   B 1 5   ? -3.305  1.921   -10.498 1.000 61.819  0 5   THR   B CB    1 ? 
ATOM   1312 O  OG1   . THR   B 1 5   ? -2.935  1.980   -9.122  1.000 62.741  0 5   THR   B OG1   1 ? 
ATOM   1313 C  CG2   . THR   B 1 5   ? -4.597  1.125   -10.577 1.000 60.540  0 5   THR   B CG2   1 ? 
ATOM   1314 N  N     . ILE   B 1 6   ? -0.758  3.131   -11.871 1.000 58.668  0 6   ILE   B N     1 ? 
ATOM   1315 C  CA    . ILE   B 1 6   ? 0.428   3.964   -11.809 1.000 55.628  0 6   ILE   B CA    1 ? 
ATOM   1316 C  C     . ILE   B 1 6   ? 0.045   5.434   -11.674 1.000 54.580  0 6   ILE   B C     1 ? 
ATOM   1317 O  O     . ILE   B 1 6   ? -1.097  5.819   -11.870 1.000 50.629  0 6   ILE   B O     1 ? 
ATOM   1318 C  CB    . ILE   B 1 6   ? 1.369   3.743   -13.008 1.000 60.114  0 6   ILE   B CB    1 ? 
ATOM   1319 C  CG1   . ILE   B 1 6   ? 0.670   3.948   -14.338 1.000 64.805  0 6   ILE   B CG1   1 ? 
ATOM   1320 C  CG2   . ILE   B 1 6   ? 2.012   2.372   -12.955 1.000 67.510  0 6   ILE   B CG2   1 ? 
ATOM   1321 C  CD1   . ILE   B 1 6   ? 0.776   5.349   -14.888 1.000 65.226  0 6   ILE   B CD1   1 ? 
ATOM   1322 N  N     . TYR   B 1 7   ? 1.048   6.238   -11.301 1.000 51.435  0 7   TYR   B N     1 ? 
ATOM   1323 C  CA    . TYR   B 1 7   ? 1.009   7.672   -11.471 1.000 54.755  0 7   TYR   B CA    1 ? 
ATOM   1324 C  C     . TYR   B 1 7   ? 1.894   7.983   -12.667 1.000 48.682  0 7   TYR   B C     1 ? 
ATOM   1325 O  O     . TYR   B 1 7   ? 3.055   7.584   -12.685 1.000 53.286  0 7   TYR   B O     1 ? 
ATOM   1326 C  CB    . TYR   B 1 7   ? 1.510   8.384   -10.207 1.000 53.094  0 7   TYR   B CB    1 ? 
ATOM   1327 C  CG    . TYR   B 1 7   ? 1.635   9.903   -10.290 1.000 48.786  0 7   TYR   B CG    1 ? 
ATOM   1328 C  CD1   . TYR   B 1 7   ? 2.799   10.511  -10.750 1.000 50.275  0 7   TYR   B CD1   1 ? 
ATOM   1329 C  CD2   . TYR   B 1 7   ? 0.614   10.731  -9.852  1.000 52.731  0 7   TYR   B CD2   1 ? 
ATOM   1330 C  CE1   . TYR   B 1 7   ? 2.931   11.896  -10.795 1.000 56.854  0 7   TYR   B CE1   1 ? 
ATOM   1331 C  CE2   . TYR   B 1 7   ? 0.730   12.116  -9.907  1.000 48.549  0 7   TYR   B CE2   1 ? 
ATOM   1332 C  CZ    . TYR   B 1 7   ? 1.897   12.703  -10.355 1.000 48.623  0 7   TYR   B CZ    1 ? 
ATOM   1333 O  OH    . TYR   B 1 7   ? 2.002   14.071  -10.431 1.000 56.774  0 7   TYR   B OH    1 ? 
ATOM   1334 N  N     . PHE   B 1 8   ? 1.331   8.734   -13.620 1.000 57.650  0 8   PHE   B N     1 ? 
ATOM   1335 C  CA    . PHE   B 1 8   ? 2.011   9.084   -14.853 1.000 55.952  0 8   PHE   B CA    1 ? 
ATOM   1336 C  C     . PHE   B 1 8   ? 2.833   10.350  -14.645 1.000 53.047  0 8   PHE   B C     1 ? 
ATOM   1337 O  O     . PHE   B 1 8   ? 2.412   11.455  -14.998 1.000 56.055  0 8   PHE   B O     1 ? 
ATOM   1338 C  CB    . PHE   B 1 8   ? 0.982   9.258   -15.977 1.000 61.197  0 8   PHE   B CB    1 ? 
ATOM   1339 C  CG    . PHE   B 1 8   ? 1.610   9.237   -17.365 1.000 60.154  0 8   PHE   B CG    1 ? 
ATOM   1340 C  CD1   . PHE   B 1 8   ? 1.960   8.038   -17.960 1.000 57.616  0 8   PHE   B CD1   1 ? 
ATOM   1341 C  CD2   . PHE   B 1 8   ? 1.890   10.411  -18.051 1.000 72.935  0 8   PHE   B CD2   1 ? 
ATOM   1342 C  CE1   . PHE   B 1 8   ? 2.560   8.004   -19.210 1.000 63.159  0 8   PHE   B CE1   1 ? 
ATOM   1343 C  CE2   . PHE   B 1 8   ? 2.475   10.369  -19.314 1.000 79.244  0 8   PHE   B CE2   1 ? 
ATOM   1344 C  CZ    . PHE   B 1 8   ? 2.822   9.168   -19.886 1.000 65.166  0 8   PHE   B CZ    1 ? 
ATOM   1345 N  N     . GLY   B 1 9   ? 4.043   10.159  -14.132 1.000 53.200  0 9   GLY   B N     1 ? 
ATOM   1346 C  CA    . GLY   B 1 9   ? 4.983   11.262  -13.952 1.000 59.746  0 9   GLY   B CA    1 ? 
ATOM   1347 C  C     . GLY   B 1 9   ? 5.746   11.604  -15.228 1.000 60.133  0 9   GLY   B C     1 ? 
ATOM   1348 O  O     . GLY   B 1 9   ? 6.682   10.908  -15.593 1.000 64.505  0 9   GLY   B O     1 ? 
ATOM   1349 N  N     . ALA   B 1 10  ? 5.366   12.706  -15.879 1.000 70.842  0 10  ALA   B N     1 ? 
ATOM   1350 C  CA    . ALA   B 1 10  ? 5.904   13.082  -17.175 1.000 68.168  0 10  ALA   B CA    1 ? 
ATOM   1351 C  C     . ALA   B 1 10  ? 5.683   14.569  -17.406 1.000 76.585  0 10  ALA   B C     1 ? 
ATOM   1352 O  O     . ALA   B 1 10  ? 4.559   15.030  -17.239 1.000 82.059  0 10  ALA   B O     1 ? 
ATOM   1353 C  CB    . ALA   B 1 10  ? 5.199   12.292  -18.227 1.000 68.087  0 10  ALA   B CB    1 ? 
ATOM   1354 N  N     . GLY   B 1 11  ? 6.748   15.294  -17.776 1.000 75.271  0 11  GLY   B N     1 ? 
ATOM   1355 C  CA    . GLY   B 1 11  ? 6.624   16.682  -18.204 1.000 78.268  0 11  GLY   B CA    1 ? 
ATOM   1356 C  C     . GLY   B 1 11  ? 5.871   16.795  -19.532 1.000 76.616  0 11  GLY   B C     1 ? 
ATOM   1357 O  O     . GLY   B 1 11  ? 5.778   15.828  -20.290 1.000 76.936  0 11  GLY   B O     1 ? 
ATOM   1358 N  N     . TRP   B 1 12  ? 5.339   17.992  -19.807 1.000 82.308  0 12  TRP   B N     1 ? 
ATOM   1359 C  CA    . TRP   B 1 12  ? 4.624   18.251  -21.048 1.000 76.934  0 12  TRP   B CA    1 ? 
ATOM   1360 C  C     . TRP   B 1 12  ? 4.988   19.630  -21.593 1.000 81.722  0 12  TRP   B C     1 ? 
ATOM   1361 O  O     . TRP   B 1 12  ? 4.149   20.275  -22.209 1.000 71.938  0 12  TRP   B O     1 ? 
ATOM   1362 C  CB    . TRP   B 1 12  ? 3.109   18.108  -20.834 1.000 81.533  0 12  TRP   B CB    1 ? 
ATOM   1363 C  CG    . TRP   B 1 12  ? 2.541   18.966  -19.739 1.000 92.590  0 12  TRP   B CG    1 ? 
ATOM   1364 C  CD1   . TRP   B 1 12  ? 2.229   20.290  -19.824 1.000 102.563 0 12  TRP   B CD1   1 ? 
ATOM   1365 C  CD2   . TRP   B 1 12  ? 2.210   18.563  -18.392 1.000 99.970  0 12  TRP   B CD2   1 ? 
ATOM   1366 N  NE1   . TRP   B 1 12  ? 1.739   20.738  -18.629 1.000 97.397  0 12  TRP   B NE1   1 ? 
ATOM   1367 C  CE2   . TRP   B 1 12  ? 1.713   19.705  -17.733 1.000 98.084  0 12  TRP   B CE2   1 ? 
ATOM   1368 C  CE3   . TRP   B 1 12  ? 2.285   17.363  -17.679 1.000 96.989  0 12  TRP   B CE3   1 ? 
ATOM   1369 C  CZ2   . TRP   B 1 12  ? 1.300   19.682  -16.405 1.000 94.874  0 12  TRP   B CZ2   1 ? 
ATOM   1370 C  CZ3   . TRP   B 1 12  ? 1.875   17.340  -16.364 1.000 108.313 0 12  TRP   B CZ3   1 ? 
ATOM   1371 C  CH2   . TRP   B 1 12  ? 1.393   18.487  -15.738 1.000 99.548  0 12  TRP   B CH2   1 ? 
ATOM   1372 N  N     . PHE   B 1 13  ? 6.264   20.023  -21.434 1.000 86.665  0 13  PHE   B N     1 ? 
ATOM   1373 C  CA    . PHE   B 1 13  ? 6.698   21.402  -21.636 1.000 98.672  0 13  PHE   B CA    1 ? 
ATOM   1374 C  C     . PHE   B 1 13  ? 7.634   21.559  -22.837 1.000 98.230  0 13  PHE   B C     1 ? 
ATOM   1375 O  O     . PHE   B 1 13  ? 7.999   22.686  -23.139 1.000 116.768 0 13  PHE   B O     1 ? 
ATOM   1376 C  CB    . PHE   B 1 13  ? 7.422   21.947  -20.394 1.000 102.112 0 13  PHE   B CB    1 ? 
ATOM   1377 C  CG    . PHE   B 1 13  ? 6.671   21.679  -19.094 1.000 122.580 0 13  PHE   B CG    1 ? 
ATOM   1378 C  CD1   . PHE   B 1 13  ? 5.444   22.293  -18.845 1.000 119.428 0 13  PHE   B CD1   1 ? 
ATOM   1379 C  CD2   . PHE   B 1 13  ? 7.176   20.796  -18.136 1.000 115.495 0 13  PHE   B CD2   1 ? 
ATOM   1380 C  CE1   . PHE   B 1 13  ? 4.748   22.038  -17.670 1.000 122.337 0 13  PHE   B CE1   1 ? 
ATOM   1381 C  CE2   . PHE   B 1 13  ? 6.472   20.536  -16.970 1.000 117.589 0 13  PHE   B CE2   1 ? 
ATOM   1382 C  CZ    . PHE   B 1 13  ? 5.266   21.168  -16.731 1.000 116.294 0 13  PHE   B CZ    1 ? 
ATOM   1383 N  N     . THR   B 1 14  ? 8.042   20.454  -23.487 1.000 90.617  0 14  THR   B N     1 ? 
ATOM   1384 C  CA    . THR   B 1 14  ? 8.963   20.479  -24.619 1.000 85.076  0 14  THR   B CA    1 ? 
ATOM   1385 C  C     . THR   B 1 14  ? 8.524   19.424  -25.633 1.000 78.221  0 14  THR   B C     1 ? 
ATOM   1386 O  O     . THR   B 1 14  ? 7.667   18.588  -25.342 1.000 79.931  0 14  THR   B O     1 ? 
ATOM   1387 C  CB    . THR   B 1 14  ? 10.417  20.229  -24.207 1.000 76.147  0 14  THR   B CB    1 ? 
ATOM   1388 O  OG1   . THR   B 1 14  ? 10.475  18.853  -23.847 1.000 71.706  0 14  THR   B OG1   1 ? 
ATOM   1389 C  CG2   . THR   B 1 14  ? 10.894  21.099  -23.056 1.000 81.991  0 14  THR   B CG2   1 ? 
ATOM   1390 N  N     . ASP   B 1 15  ? 9.151   19.466  -26.815 1.000 79.950  0 15  ASP   B N     1 ? 
ATOM   1391 C  CA    . ASP   B 1 15  ? 8.820   18.550  -27.895 1.000 74.972  0 15  ASP   B CA    1 ? 
ATOM   1392 C  C     . ASP   B 1 15  ? 9.237   17.137  -27.506 1.000 66.900  0 15  ASP   B C     1 ? 
ATOM   1393 O  O     . ASP   B 1 15  ? 8.510   16.183  -27.782 1.000 69.033  0 15  ASP   B O     1 ? 
ATOM   1394 C  CB    . ASP   B 1 15  ? 9.418   18.976  -29.231 1.000 77.822  0 15  ASP   B CB    1 ? 
ATOM   1395 C  CG    . ASP   B 1 15  ? 8.933   20.319  -29.771 1.000 87.180  0 15  ASP   B CG    1 ? 
ATOM   1396 O  OD1   . ASP   B 1 15  ? 7.719   20.613  -29.601 1.000 72.929  0 15  ASP   B OD1   1 ? 
ATOM   1397 O  OD2   . ASP   B 1 15  ? 9.764   21.057  -30.368 1.000 78.952  0 15  ASP   B OD2   1 ? 
ATOM   1398 N  N     . ARG   B 1 16  ? 10.407  17.015  -26.863 1.000 62.810  0 16  ARG   B N     1 ? 
ATOM   1399 C  CA    . ARG   B 1 16  ? 10.917  15.704  -26.484 1.000 64.599  0 16  ARG   B CA    1 ? 
ATOM   1400 C  C     . ARG   B 1 16  ? 10.039  15.132  -25.373 1.000 68.801  0 16  ARG   B C     1 ? 
ATOM   1401 O  O     . ARG   B 1 16  ? 9.686   13.948  -25.401 1.000 72.354  0 16  ARG   B O     1 ? 
ATOM   1402 C  CB    . ARG   B 1 16  ? 12.390  15.772  -26.078 1.000 68.082  0 16  ARG   B CB    1 ? 
ATOM   1403 C  CG    . ARG   B 1 16  ? 13.163  16.668  -27.026 1.000 71.067  0 16  ARG   B CG    1 ? 
ATOM   1404 C  CD    . ARG   B 1 16  ? 14.584  16.895  -26.611 1.000 72.549  0 16  ARG   B CD    1 ? 
ATOM   1405 N  NE    . ARG   B 1 16  ? 15.267  15.603  -26.612 1.000 76.646  0 16  ARG   B NE    1 ? 
ATOM   1406 C  CZ    . ARG   B 1 16  ? 16.539  15.478  -26.380 1.000 71.486  0 16  ARG   B CZ    1 ? 
ATOM   1407 N  NH1   . ARG   B 1 16  ? 17.302  16.552  -26.384 1.000 76.455  0 16  ARG   B NH1   1 ? 
ATOM   1408 N  NH2   . ARG   B 1 16  ? 17.048  14.281  -26.165 1.000 83.806  0 16  ARG   B NH2   1 ? 
ATOM   1409 N  N     . GLN   B 1 17  ? 9.629   16.001  -24.438 1.000 67.942  0 17  GLN   B N     1 ? 
ATOM   1410 C  CA    . GLN   B 1 17  ? 8.726   15.588  -23.375 1.000 65.102  0 17  GLN   B CA    1 ? 
ATOM   1411 C  C     . GLN   B 1 17  ? 7.428   15.041  -23.946 1.000 62.470  0 17  GLN   B C     1 ? 
ATOM   1412 O  O     . GLN   B 1 17  ? 6.990   13.966  -23.531 1.000 64.962  0 17  GLN   B O     1 ? 
ATOM   1413 C  CB    . GLN   B 1 17  ? 8.507   16.706  -22.361 1.000 61.496  0 17  GLN   B CB    1 ? 
ATOM   1414 C  CG    . GLN   B 1 17  ? 9.671   16.832  -21.383 1.000 66.229  0 17  GLN   B CG    1 ? 
ATOM   1415 C  CD    . GLN   B 1 17  ? 9.560   18.036  -20.478 1.000 72.945  0 17  GLN   B CD    1 ? 
ATOM   1416 O  OE1   . GLN   B 1 17  ? 8.496   18.647  -20.369 1.000 72.801  0 17  GLN   B OE1   1 ? 
ATOM   1417 N  NE2   . GLN   B 1 17  ? 10.659  18.378  -19.822 1.000 81.809  0 17  GLN   B NE2   1 ? 
ATOM   1418 N  N     . ASN   B 1 18  ? 6.824   15.778  -24.886 1.000 72.268  0 18  ASN   B N     1 ? 
ATOM   1419 C  CA    . ASN   B 1 18  ? 5.515   15.410  -25.409 1.000 74.775  0 18  ASN   B CA    1 ? 
ATOM   1420 C  C     . ASN   B 1 18  ? 5.643   14.138  -26.247 1.000 72.820  0 18  ASN   B C     1 ? 
ATOM   1421 O  O     . ASN   B 1 18  ? 4.763   13.283  -26.221 1.000 71.143  0 18  ASN   B O     1 ? 
ATOM   1422 C  CB    . ASN   B 1 18  ? 4.862   16.563  -26.160 1.000 85.110  0 18  ASN   B CB    1 ? 
ATOM   1423 C  CG    . ASN   B 1 18  ? 4.345   17.647  -25.237 1.000 87.521  0 18  ASN   B CG    1 ? 
ATOM   1424 O  OD1   . ASN   B 1 18  ? 3.564   17.376  -24.316 1.000 85.548  0 18  ASN   B OD1   1 ? 
ATOM   1425 N  ND2   . ASN   B 1 18  ? 4.734   18.890  -25.481 1.000 87.001  0 18  ASN   B ND2   1 ? 
ATOM   1426 N  N     . LYS   B 1 19  ? 6.767   13.976  -26.949 1.000 69.629  0 19  LYS   B N     1 ? 
ATOM   1427 C  CA    . LYS   B 1 19  ? 6.977   12.757  -27.711 1.000 76.637  0 19  LYS   B CA    1 ? 
ATOM   1428 C  C     . LYS   B 1 19  ? 7.032   11.552  -26.770 1.000 70.319  0 19  LYS   B C     1 ? 
ATOM   1429 O  O     . LYS   B 1 19  ? 6.345   10.555  -26.996 1.000 66.645  0 19  LYS   B O     1 ? 
ATOM   1430 C  CB    . LYS   B 1 19  ? 8.251   12.894  -28.550 1.000 80.027  0 19  LYS   B CB    1 ? 
ATOM   1431 C  CG    . LYS   B 1 19  ? 8.575   11.745  -29.486 1.000 92.030  0 19  LYS   B CG    1 ? 
ATOM   1432 C  CD    . LYS   B 1 19  ? 9.709   12.124  -30.440 1.000 98.575  0 19  LYS   B CD    1 ? 
ATOM   1433 C  CE    . LYS   B 1 19  ? 9.992   11.120  -31.514 1.000 104.048 0 19  LYS   B CE    1 ? 
ATOM   1434 N  NZ    . LYS   B 1 19  ? 10.946  10.101  -31.070 1.000 99.697  0 19  LYS   B NZ    1 ? 
ATOM   1435 N  N     . ALA   B 1 20  ? 7.867   11.645  -25.721 1.000 68.848  0 20  ALA   B N     1 ? 
ATOM   1436 C  CA    . ALA   B 1 20  ? 8.057   10.541  -24.779 1.000 57.294  0 20  ALA   B CA    1 ? 
ATOM   1437 C  C     . ALA   B 1 20  ? 6.756   10.238  -24.037 1.000 56.069  0 20  ALA   B C     1 ? 
ATOM   1438 O  O     . ALA   B 1 20  ? 6.403   9.089   -23.826 1.000 56.584  0 20  ALA   B O     1 ? 
ATOM   1439 C  CB    . ALA   B 1 20  ? 9.167   10.867  -23.814 1.000 60.349  0 20  ALA   B CB    1 ? 
ATOM   1440 N  N     . TYR   B 1 21  ? 6.008   11.291  -23.719 1.000 58.434  0 21  TYR   B N     1 ? 
ATOM   1441 C  CA    . TYR   B 1 21  ? 4.712   11.163  -23.093 1.000 61.263  0 21  TYR   B CA    1 ? 
ATOM   1442 C  C     . TYR   B 1 21  ? 3.802   10.287  -23.944 1.000 69.845  0 21  TYR   B C     1 ? 
ATOM   1443 O  O     . TYR   B 1 21  ? 3.180   9.367   -23.405 1.000 62.039  0 21  TYR   B O     1 ? 
ATOM   1444 C  CB    . TYR   B 1 21  ? 4.223   12.605  -22.887 1.000 66.688  0 21  TYR   B CB    1 ? 
ATOM   1445 C  CG    . TYR   B 1 21  ? 2.907   12.772  -22.138 1.000 59.566  0 21  TYR   B CG    1 ? 
ATOM   1446 C  CD1   . TYR   B 1 21  ? 1.743   12.150  -22.559 1.000 63.606  0 21  TYR   B CD1   1 ? 
ATOM   1447 C  CD2   . TYR   B 1 21  ? 2.835   13.560  -20.997 1.000 65.139  0 21  TYR   B CD2   1 ? 
ATOM   1448 C  CE1   . TYR   B 1 21  ? 0.547   12.312  -21.874 1.000 73.053  0 21  TYR   B CE1   1 ? 
ATOM   1449 C  CE2   . TYR   B 1 21  ? 1.647   13.736  -20.304 1.000 53.598  0 21  TYR   B CE2   1 ? 
ATOM   1450 C  CZ    . TYR   B 1 21  ? 0.497   13.107  -20.739 1.000 66.430  0 21  TYR   B CZ    1 ? 
ATOM   1451 O  OH    . TYR   B 1 21  ? -0.679  13.280  -20.068 1.000 69.438  0 21  TYR   B OH    1 ? 
ATOM   1452 N  N     . LYS   B 1 22  ? 3.703   10.596  -25.254 1.000 77.877  0 22  LYS   B N     1 ? 
ATOM   1453 C  CA    . LYS   B 1 22  ? 2.770   9.910   -26.147 1.000 71.038  0 22  LYS   B CA    1 ? 
ATOM   1454 C  C     . LYS   B 1 22  ? 3.187   8.450   -26.234 1.000 61.605  0 22  LYS   B C     1 ? 
ATOM   1455 O  O     . LYS   B 1 22  ? 2.349   7.566   -26.110 1.000 63.543  0 22  LYS   B O     1 ? 
ATOM   1456 C  CB    . LYS   B 1 22  ? 2.663   10.495  -27.568 1.000 88.316  0 22  LYS   B CB    1 ? 
ATOM   1457 C  CG    . LYS   B 1 22  ? 1.499   11.469  -27.863 1.000 97.471  0 22  LYS   B CG    1 ? 
ATOM   1458 C  CD    . LYS   B 1 22  ? 1.728   12.469  -29.003 1.000 94.473  0 22  LYS   B CD    1 ? 
ATOM   1459 N  N     . GLU   B 1 23  ? 4.502   8.223   -26.382 1.000 66.183  0 23  GLU   B N     1 ? 
ATOM   1460 C  CA    . GLU   B 1 23  ? 5.054   6.882   -26.482 1.000 62.069  0 23  GLU   B CA    1 ? 
ATOM   1461 C  C     . GLU   B 1 23  ? 4.784   6.076   -25.217 1.000 68.624  0 23  GLU   B C     1 ? 
ATOM   1462 O  O     . GLU   B 1 23  ? 4.394   4.917   -25.296 1.000 67.495  0 23  GLU   B O     1 ? 
ATOM   1463 C  CB    . GLU   B 1 23  ? 6.560   6.941   -26.731 1.000 71.773  0 23  GLU   B CB    1 ? 
ATOM   1464 C  CG    . GLU   B 1 23  ? 6.919   7.390   -28.143 1.000 78.862  0 23  GLU   B CG    1 ? 
ATOM   1465 C  CD    . GLU   B 1 23  ? 8.390   7.669   -28.393 1.000 80.205  0 23  GLU   B CD    1 ? 
ATOM   1466 O  OE1   . GLU   B 1 23  ? 8.588   8.092   -29.548 1.000 85.246  0 23  GLU   B OE1   1 ? 
ATOM   1467 O  OE2   . GLU   B 1 23  ? 9.288   7.527   -27.507 1.000 85.548  0 23  GLU   B OE2   1 ? 
ATOM   1468 N  N     . ALA   B 1 24  ? 5.007   6.686   -24.049 1.000 67.434  0 24  ALA   B N     1 ? 
ATOM   1469 C  CA    . ALA   B 1 24  ? 4.864   5.972   -22.786 1.000 67.972  0 24  ALA   B CA    1 ? 
ATOM   1470 C  C     . ALA   B 1 24  ? 3.405   5.598   -22.559 1.000 57.543  0 24  ALA   B C     1 ? 
ATOM   1471 O  O     . ALA   B 1 24  ? 3.100   4.511   -22.083 1.000 60.443  0 24  ALA   B O     1 ? 
ATOM   1472 C  CB    . ALA   B 1 24  ? 5.408   6.811   -21.632 1.000 59.875  0 24  ALA   B CB    1 ? 
ATOM   1473 N  N     . MET   B 1 25  ? 2.503   6.520   -22.897 1.000 59.690  0 25  MET   B N     1 ? 
ATOM   1474 C  CA    . MET   B 1 25  ? 1.083   6.287   -22.739 1.000 65.423  0 25  MET   B CA    1 ? 
ATOM   1475 C  C     . MET   B 1 25  ? 0.676   5.127   -23.647 1.000 72.980  0 25  MET   B C     1 ? 
ATOM   1476 O  O     . MET   B 1 25  ? -0.028  4.241   -23.185 1.000 76.861  0 25  MET   B O     1 ? 
ATOM   1477 C  CB    . MET   B 1 25  ? 0.305   7.574   -23.032 1.000 66.470  0 25  MET   B CB    1 ? 
ATOM   1478 C  CG    . MET   B 1 25  ? -1.101  7.594   -22.481 1.000 71.879  0 25  MET   B CG    1 ? 
ATOM   1479 S  SD    . MET   B 1 25  ? -1.274  7.473   -20.684 1.000 75.559  0 25  MET   B SD    1 ? 
ATOM   1480 C  CE    . MET   B 1 25  ? -0.862  9.162   -20.227 1.000 85.004  0 25  MET   B CE    1 ? 
ATOM   1481 N  N     . GLU   B 1 26  ? 1.171   5.091   -24.898 1.000 73.473  0 26  GLU   B N     1 ? 
ATOM   1482 C  CA    . GLU   B 1 26  ? 0.881   3.997   -25.827 1.000 78.277  0 26  GLU   B CA    1 ? 
ATOM   1483 C  C     . GLU   B 1 26  ? 1.399   2.670   -25.266 1.000 78.131  0 26  GLU   B C     1 ? 
ATOM   1484 O  O     . GLU   B 1 26  ? 0.704   1.659   -25.342 1.000 70.034  0 26  GLU   B O     1 ? 
ATOM   1485 C  CB    . GLU   B 1 26  ? 1.465   4.195   -27.237 1.000 81.425  0 26  GLU   B CB    1 ? 
ATOM   1486 C  CG    . GLU   B 1 26  ? 0.757   5.251   -28.090 1.000 104.324 0 26  GLU   B CG    1 ? 
ATOM   1487 C  CD    . GLU   B 1 26  ? 1.606   5.983   -29.142 1.000 121.692 0 26  GLU   B CD    1 ? 
ATOM   1488 O  OE1   . GLU   B 1 26  ? 2.532   5.365   -29.729 1.000 102.584 0 26  GLU   B OE1   1 ? 
ATOM   1489 O  OE2   . GLU   B 1 26  ? 1.340   7.188   -29.404 1.000 115.853 0 26  GLU   B OE2   1 ? 
ATOM   1490 N  N     . ALA   B 1 27  ? 2.624   2.659   -24.713 1.000 64.744  0 27  ALA   B N     1 ? 
ATOM   1491 C  CA    . ALA   B 1 27  ? 3.177   1.435   -24.146 1.000 64.818  0 27  ALA   B CA    1 ? 
ATOM   1492 C  C     . ALA   B 1 27  ? 2.310   0.937   -22.992 1.000 68.414  0 27  ALA   B C     1 ? 
ATOM   1493 O  O     . ALA   B 1 27  ? 2.022   -0.252  -22.910 1.000 65.728  0 27  ALA   B O     1 ? 
ATOM   1494 C  CB    . ALA   B 1 27  ? 4.613   1.636   -23.713 1.000 63.658  0 27  ALA   B CB    1 ? 
ATOM   1495 N  N     . LEU   B 1 28  ? 1.852   1.849   -22.129 1.000 63.894  0 28  LEU   B N     1 ? 
ATOM   1496 C  CA    . LEU   B 1 28  ? 1.001   1.464   -21.010 1.000 72.491  0 28  LEU   B CA    1 ? 
ATOM   1497 C  C     . LEU   B 1 28  ? -0.328  0.875   -21.489 1.000 70.353  0 28  LEU   B C     1 ? 
ATOM   1498 O  O     . LEU   B 1 28  ? -0.815  -0.080  -20.885 1.000 74.902  0 28  LEU   B O     1 ? 
ATOM   1499 C  CB    . LEU   B 1 28  ? 0.757   2.630   -20.055 1.000 76.224  0 28  LEU   B CB    1 ? 
ATOM   1500 C  CG    . LEU   B 1 28  ? 1.986   3.148   -19.302 1.000 76.074  0 28  LEU   B CG    1 ? 
ATOM   1501 C  CD1   . LEU   B 1 28  ? 1.641   4.456   -18.609 1.000 74.815  0 28  LEU   B CD1   1 ? 
ATOM   1502 C  CD2   . LEU   B 1 28  ? 2.491   2.110   -18.314 1.000 73.661  0 28  LEU   B CD2   1 ? 
ATOM   1503 N  N     . LYS   B 1 29  ? -0.932  1.447   -22.538 1.000 71.808  0 29  LYS   B N     1 ? 
ATOM   1504 C  CA    . LYS   B 1 29  ? -2.184  0.922   -23.079 1.000 74.455  0 29  LYS   B CA    1 ? 
ATOM   1505 C  C     . LYS   B 1 29  ? -2.020  -0.553  -23.483 1.000 77.340  0 29  LYS   B C     1 ? 
ATOM   1506 O  O     . LYS   B 1 29  ? -2.957  -1.331  -23.337 1.000 71.027  0 29  LYS   B O     1 ? 
ATOM   1507 C  CB    . LYS   B 1 29  ? -2.681  1.713   -24.298 1.000 75.961  0 29  LYS   B CB    1 ? 
ATOM   1508 C  CG    . LYS   B 1 29  ? -3.099  3.176   -24.123 1.000 76.835  0 29  LYS   B CG    1 ? 
ATOM   1509 N  N     . GLU   B 1 30  ? -0.823  -0.937  -23.962 1.000 75.018  0 30  GLU   B N     1 ? 
ATOM   1510 C  CA    . GLU   B 1 30  ? -0.546  -2.281  -24.455 1.000 83.149  0 30  GLU   B CA    1 ? 
ATOM   1511 C  C     . GLU   B 1 30  ? -0.031  -3.209  -23.344 1.000 78.580  0 30  GLU   B C     1 ? 
ATOM   1512 O  O     . GLU   B 1 30  ? 0.121   -4.400  -23.562 1.000 73.150  0 30  GLU   B O     1 ? 
ATOM   1513 C  CB    . GLU   B 1 30  ? 0.422   -2.223  -25.652 1.000 87.320  0 30  GLU   B CB    1 ? 
ATOM   1514 C  CG    . GLU   B 1 30  ? -0.256  -2.034  -27.013 1.000 81.753  0 30  GLU   B CG    1 ? 
ATOM   1515 N  N     . ASN   B 1 31  ? 0.255   -2.701  -22.142 1.000 86.099  0 31  ASN   B N     1 ? 
ATOM   1516 C  CA    . ASN   B 1 31  ? 0.860   -3.541  -21.115 1.000 69.647  0 31  ASN   B CA    1 ? 
ATOM   1517 C  C     . ASN   B 1 31  ? -0.243  -4.214  -20.305 1.000 69.078  0 31  ASN   B C     1 ? 
ATOM   1518 O  O     . ASN   B 1 31  ? -1.050  -3.548  -19.658 1.000 75.867  0 31  ASN   B O     1 ? 
ATOM   1519 C  CB    . ASN   B 1 31  ? 1.788   -2.749  -20.203 1.000 64.737  0 31  ASN   B CB    1 ? 
ATOM   1520 C  CG    . ASN   B 1 31  ? 2.585   -3.637  -19.276 1.000 59.636  0 31  ASN   B CG    1 ? 
ATOM   1521 O  OD1   . ASN   B 1 31  ? 2.020   -4.498  -18.584 1.000 62.700  0 31  ASN   B OD1   1 ? 
ATOM   1522 N  ND2   . ASN   B 1 31  ? 3.894   -3.429  -19.232 1.000 56.949  0 31  ASN   B ND2   1 ? 
ATOM   1523 N  N     . PRO   B 1 32  ? -0.324  -5.561  -20.304 1.000 66.467  0 32  PRO   B N     1 ? 
ATOM   1524 C  CA    . PRO   B 1 32  ? -1.434  -6.238  -19.630 1.000 70.299  0 32  PRO   B CA    1 ? 
ATOM   1525 C  C     . PRO   B 1 32  ? -1.363  -6.317  -18.108 1.000 70.603  0 32  PRO   B C     1 ? 
ATOM   1526 O  O     . PRO   B 1 32  ? -2.308  -6.819  -17.507 1.000 63.522  0 32  PRO   B O     1 ? 
ATOM   1527 C  CB    . PRO   B 1 32  ? -1.383  -7.654  -20.269 1.000 71.207  0 32  PRO   B CB    1 ? 
ATOM   1528 C  CG    . PRO   B 1 32  ? 0.089   -7.876  -20.628 1.000 63.450  0 32  PRO   B CG    1 ? 
ATOM   1529 C  CD    . PRO   B 1 32  ? 0.592   -6.489  -20.996 1.000 62.923  0 32  PRO   B CD    1 ? 
ATOM   1530 N  N     . THR   B 1 33  ? -0.260  -5.844  -17.488 1.000 66.944  0 33  THR   B N     1 ? 
ATOM   1531 C  CA    . THR   B 1 33  ? -0.172  -5.824  -16.026 1.000 65.729  0 33  THR   B CA    1 ? 
ATOM   1532 C  C     . THR   B 1 33  ? -0.560  -4.449  -15.466 1.000 63.582  0 33  THR   B C     1 ? 
ATOM   1533 O  O     . THR   B 1 33  ? -0.494  -4.240  -14.258 1.000 68.383  0 33  THR   B O     1 ? 
ATOM   1534 C  CB    . THR   B 1 33  ? 1.216   -6.272  -15.542 1.000 65.893  0 33  THR   B CB    1 ? 
ATOM   1535 O  OG1   . THR   B 1 33  ? 2.242   -5.408  -16.039 1.000 52.552  0 33  THR   B OG1   1 ? 
ATOM   1536 C  CG2   . THR   B 1 33  ? 1.566   -7.684  -15.985 1.000 66.229  0 33  THR   B CG2   1 ? 
ATOM   1537 N  N     . ILE   B 1 34  ? -1.007  -3.531  -16.334 1.000 58.520  0 34  ILE   B N     1 ? 
ATOM   1538 C  CA    . ILE   B 1 34  ? -1.336  -2.167  -15.955 1.000 66.175  0 34  ILE   B CA    1 ? 
ATOM   1539 C  C     . ILE   B 1 34  ? -2.833  -1.917  -16.131 1.000 67.947  0 34  ILE   B C     1 ? 
ATOM   1540 O  O     . ILE   B 1 34  ? -3.392  -2.217  -17.172 1.000 62.526  0 34  ILE   B O     1 ? 
ATOM   1541 C  CB    . ILE   B 1 34  ? -0.523  -1.169  -16.796 1.000 59.744  0 34  ILE   B CB    1 ? 
ATOM   1542 C  CG1   . ILE   B 1 34  ? 0.945   -1.123  -16.385 1.000 66.910  0 34  ILE   B CG1   1 ? 
ATOM   1543 C  CG2   . ILE   B 1 34  ? -1.161  0.219   -16.771 1.000 68.166  0 34  ILE   B CG2   1 ? 
ATOM   1544 C  CD1   . ILE   B 1 34  ? 1.176   -0.719  -14.939 1.000 67.237  0 34  ILE   B CD1   1 ? 
ATOM   1545 N  N     . ASP   B 1 35  ? -3.462  -1.343  -15.103 1.000 66.255  0 35  ASP   B N     1 ? 
ATOM   1546 C  CA    . ASP   B 1 35  ? -4.819  -0.825  -15.199 1.000 64.826  0 35  ASP   B CA    1 ? 
ATOM   1547 C  C     . ASP   B 1 35  ? -4.715  0.674   -15.412 1.000 63.719  0 35  ASP   B C     1 ? 
ATOM   1548 O  O     . ASP   B 1 35  ? -4.625  1.425   -14.447 1.000 62.651  0 35  ASP   B O     1 ? 
ATOM   1549 C  CB    . ASP   B 1 35  ? -5.664  -1.180  -13.984 1.000 62.655  0 35  ASP   B CB    1 ? 
ATOM   1550 C  CG    . ASP   B 1 35  ? -7.028  -0.504  -13.868 1.000 67.363  0 35  ASP   B CG    1 ? 
ATOM   1551 O  OD1   . ASP   B 1 35  ? -7.338  0.347   -14.736 1.000 66.205  0 35  ASP   B OD1   1 ? 
ATOM   1552 O  OD2   . ASP   B 1 35  ? -7.762  -0.827  -12.898 1.000 61.289  0 35  ASP   B OD2   1 ? 
ATOM   1553 N  N     . LEU   B 1 36  ? -4.703  1.074   -16.685 1.000 57.278  0 36  LEU   B N     1 ? 
ATOM   1554 C  CA    . LEU   B 1 36  ? -4.483  2.455   -17.062 1.000 62.262  0 36  LEU   B CA    1 ? 
ATOM   1555 C  C     . LEU   B 1 36  ? -5.713  3.295   -16.749 1.000 65.697  0 36  LEU   B C     1 ? 
ATOM   1556 O  O     . LEU   B 1 36  ? -5.582  4.481   -16.461 1.000 66.936  0 36  LEU   B O     1 ? 
ATOM   1557 C  CB    . LEU   B 1 36  ? -4.132  2.549   -18.546 1.000 68.999  0 36  LEU   B CB    1 ? 
ATOM   1558 C  CG    . LEU   B 1 36  ? -3.904  3.964   -19.095 1.000 72.259  0 36  LEU   B CG    1 ? 
ATOM   1559 C  CD1   . LEU   B 1 36  ? -2.765  4.661   -18.362 1.000 74.457  0 36  LEU   B CD1   1 ? 
ATOM   1560 C  CD2   . LEU   B 1 36  ? -3.635  3.923   -20.583 1.000 80.094  0 36  LEU   B CD2   1 ? 
ATOM   1561 N  N     . GLU   B 1 37  ? -6.902  2.694   -16.833 1.000 68.954  0 37  GLU   B N     1 ? 
ATOM   1562 C  CA    . GLU   B 1 37  ? -8.128  3.442   -16.632 1.000 62.318  0 37  GLU   B CA    1 ? 
ATOM   1563 C  C     . GLU   B 1 37  ? -8.146  4.008   -15.214 1.000 64.993  0 37  GLU   B C     1 ? 
ATOM   1564 O  O     . GLU   B 1 37  ? -8.637  5.116   -15.015 1.000 62.626  0 37  GLU   B O     1 ? 
ATOM   1565 C  CB    . GLU   B 1 37  ? -9.333  2.542   -16.912 1.000 72.953  0 37  GLU   B CB    1 ? 
ATOM   1566 C  CG    . GLU   B 1 37  ? -10.703 3.132   -16.573 1.000 79.166  0 37  GLU   B CG    1 ? 
ATOM   1567 C  CD    . GLU   B 1 37  ? -11.157 4.327   -17.399 1.000 85.183  0 37  GLU   B CD    1 ? 
ATOM   1568 O  OE1   . GLU   B 1 37  ? -10.419 4.847   -18.266 1.000 86.695  0 37  GLU   B OE1   1 ? 
ATOM   1569 O  OE2   . GLU   B 1 37  ? -12.298 4.749   -17.148 1.000 87.761  0 37  GLU   B OE2   1 ? 
ATOM   1570 N  N     . ASN   B 1 38  ? -7.669  3.228   -14.227 1.000 56.212  0 38  ASN   B N     1 ? 
ATOM   1571 C  CA    . ASN   B 1 38  ? -7.777  3.633   -12.831 1.000 64.693  0 38  ASN   B CA    1 ? 
ATOM   1572 C  C     . ASN   B 1 38  ? -6.445  4.204   -12.317 1.000 68.598  0 38  ASN   B C     1 ? 
ATOM   1573 O  O     . ASN   B 1 38  ? -6.281  4.433   -11.109 1.000 69.304  0 38  ASN   B O     1 ? 
ATOM   1574 C  CB    . ASN   B 1 38  ? -8.314  2.496   -11.967 1.000 67.483  0 38  ASN   B CB    1 ? 
ATOM   1575 C  CG    . ASN   B 1 38  ? -9.708  2.061   -12.368 1.000 73.089  0 38  ASN   B CG    1 ? 
ATOM   1576 O  OD1   . ASN   B 1 38  ? -9.922  0.856   -12.554 1.000 73.422  0 38  ASN   B OD1   1 ? 
ATOM   1577 N  ND2   . ASN   B 1 38  ? -10.667 2.978   -12.465 1.000 66.149  0 38  ASN   B ND2   1 ? 
ATOM   1578 N  N     . SER   B 1 39  ? -5.501  4.441   -13.245 1.000 59.179  0 39  SER   B N     1 ? 
ATOM   1579 C  CA    . SER   B 1 39  ? -4.265  5.148   -12.962 1.000 56.060  0 39  SER   B CA    1 ? 
ATOM   1580 C  C     . SER   B 1 39  ? -4.506  6.653   -12.923 1.000 60.718  0 39  SER   B C     1 ? 
ATOM   1581 O  O     . SER   B 1 39  ? -5.524  7.141   -13.406 1.000 60.421  0 39  SER   B O     1 ? 
ATOM   1582 C  CB    . SER   B 1 39  ? -3.244  4.812   -13.984 1.000 49.848  0 39  SER   B CB    1 ? 
ATOM   1583 O  OG    . SER   B 1 39  ? -2.878  3.438   -13.919 1.000 56.138  0 39  SER   B OG    1 ? 
ATOM   1584 N  N     . TYR   B 1 40  ? -3.536  7.388   -12.375 1.000 60.842  0 40  TYR   B N     1 ? 
ATOM   1585 C  CA    . TYR   B 1 40  ? -3.663  8.830   -12.230 1.000 56.259  0 40  TYR   B CA    1 ? 
ATOM   1586 C  C     . TYR   B 1 40  ? -2.786  9.488   -13.290 1.000 54.283  0 40  TYR   B C     1 ? 
ATOM   1587 O  O     . TYR   B 1 40  ? -1.567  9.328   -13.293 1.000 60.737  0 40  TYR   B O     1 ? 
ATOM   1588 C  CB    . TYR   B 1 40  ? -3.317  9.358   -10.829 1.000 52.863  0 40  TYR   B CB    1 ? 
ATOM   1589 C  CG    . TYR   B 1 40  ? -3.541  10.859  -10.633 1.000 54.645  0 40  TYR   B CG    1 ? 
ATOM   1590 C  CD1   . TYR   B 1 40  ? -2.542  11.781  -10.944 1.000 55.552  0 40  TYR   B CD1   1 ? 
ATOM   1591 C  CD2   . TYR   B 1 40  ? -4.742  11.360  -10.128 1.000 53.612  0 40  TYR   B CD2   1 ? 
ATOM   1592 C  CE1   . TYR   B 1 40  ? -2.732  13.146  -10.763 1.000 54.666  0 40  TYR   B CE1   1 ? 
ATOM   1593 C  CE2   . TYR   B 1 40  ? -4.948  12.724  -9.955  1.000 56.567  0 40  TYR   B CE2   1 ? 
ATOM   1594 C  CZ    . TYR   B 1 40  ? -3.943  13.623  -10.274 1.000 64.869  0 40  TYR   B CZ    1 ? 
ATOM   1595 O  OH    . TYR   B 1 40  ? -4.151  14.973  -10.109 1.000 71.985  0 40  TYR   B OH    1 ? 
ATOM   1596 N  N     . VAL   B 1 41  ? -3.459  10.233  -14.167 1.000 66.365  0 41  VAL   B N     1 ? 
ATOM   1597 C  CA    . VAL   B 1 41  ? -2.836  10.995  -15.222 1.000 69.013  0 41  VAL   B CA    1 ? 
ATOM   1598 C  C     . VAL   B 1 41  ? -3.011  12.462  -14.861 1.000 64.509  0 41  VAL   B C     1 ? 
ATOM   1599 O  O     . VAL   B 1 41  ? -4.111  13.002  -14.964 1.000 70.464  0 41  VAL   B O     1 ? 
ATOM   1600 C  CB    . VAL   B 1 41  ? -3.463  10.688  -16.595 1.000 67.112  0 41  VAL   B CB    1 ? 
ATOM   1601 C  CG1   . VAL   B 1 41  ? -2.713  11.444  -17.687 1.000 69.578  0 41  VAL   B CG1   1 ? 
ATOM   1602 C  CG2   . VAL   B 1 41  ? -3.504  9.194   -16.877 1.000 63.846  0 41  VAL   B CG2   1 ? 
ATOM   1603 N  N     . PRO   B 1 42  ? -1.940  13.168  -14.454 1.000 59.584  0 42  PRO   B N     1 ? 
ATOM   1604 C  CA    . PRO   B 1 42  ? -2.083  14.572  -14.071 1.000 70.078  0 42  PRO   B CA    1 ? 
ATOM   1605 C  C     . PRO   B 1 42  ? -2.891  15.417  -15.054 1.000 75.164  0 42  PRO   B C     1 ? 
ATOM   1606 O  O     . PRO   B 1 42  ? -3.822  16.139  -14.672 1.000 74.362  0 42  PRO   B O     1 ? 
ATOM   1607 C  CB    . PRO   B 1 42  ? -0.625  15.003  -13.985 1.000 64.338  0 42  PRO   B CB    1 ? 
ATOM   1608 C  CG    . PRO   B 1 42  ? 0.080   13.746  -13.521 1.000 59.095  0 42  PRO   B CG    1 ? 
ATOM   1609 C  CD    . PRO   B 1 42  ? -0.564  12.658  -14.344 1.000 56.039  0 42  PRO   B CD    1 ? 
ATOM   1610 N  N     . LEU   B 1 43  ? -2.556  15.280  -16.335 1.000 81.190  0 43  LEU   B N     1 ? 
ATOM   1611 C  CA    . LEU   B 1 43  ? -3.050  16.239  -17.308 1.000 88.868  0 43  LEU   B CA    1 ? 
ATOM   1612 C  C     . LEU   B 1 43  ? -4.563  16.095  -17.481 1.000 84.619  0 43  LEU   B C     1 ? 
ATOM   1613 O  O     . LEU   B 1 43  ? -5.214  17.046  -17.885 1.000 98.851  0 43  LEU   B O     1 ? 
ATOM   1614 C  CB    . LEU   B 1 43  ? -2.278  16.092  -18.613 1.000 87.906  0 43  LEU   B CB    1 ? 
ATOM   1615 C  CG    . LEU   B 1 43  ? -1.824  17.392  -19.284 1.000 93.441  0 43  LEU   B CG    1 ? 
ATOM   1616 C  CD1   . LEU   B 1 43  ? -1.287  18.478  -18.350 1.000 88.727  0 43  LEU   B CD1   1 ? 
ATOM   1617 C  CD2   . LEU   B 1 43  ? -0.746  16.987  -20.294 1.000 93.911  0 43  LEU   B CD2   1 ? 
ATOM   1618 N  N     . ASP   B 1 44  ? -5.136  14.943  -17.102 1.000 79.348  0 44  ASP   B N     1 ? 
ATOM   1619 C  CA    . ASP   B 1 44  ? -6.575  14.730  -17.137 1.000 79.326  0 44  ASP   B CA    1 ? 
ATOM   1620 C  C     . ASP   B 1 44  ? -7.229  14.947  -15.770 1.000 85.012  0 44  ASP   B C     1 ? 
ATOM   1621 O  O     . ASP   B 1 44  ? -8.401  14.619  -15.599 1.000 78.180  0 44  ASP   B O     1 ? 
ATOM   1622 C  CB    . ASP   B 1 44  ? -6.924  13.294  -17.508 1.000 92.710  0 44  ASP   B CB    1 ? 
ATOM   1623 C  CG    . ASP   B 1 44  ? -6.306  12.726  -18.780 1.000 89.327  0 44  ASP   B CG    1 ? 
ATOM   1624 O  OD1   . ASP   B 1 44  ? -5.904  13.514  -19.658 1.000 91.607  0 44  ASP   B OD1   1 ? 
ATOM   1625 O  OD2   . ASP   B 1 44  ? -6.198  11.490  -18.866 1.000 89.312  0 44  ASP   B OD2   1 ? 
ATOM   1626 N  N     . ASN   B 1 45  ? -6.493  15.479  -14.790 1.000 84.974  0 45  ASN   B N     1 ? 
ATOM   1627 C  CA    . ASN   B 1 45  ? -7.021  15.647  -13.440 1.000 88.665  0 45  ASN   B CA    1 ? 
ATOM   1628 C  C     . ASN   B 1 45  ? -6.792  17.092  -12.996 1.000 102.279 0 45  ASN   B C     1 ? 
ATOM   1629 O  O     . ASN   B 1 45  ? -6.368  17.368  -11.867 1.000 97.448  0 45  ASN   B O     1 ? 
ATOM   1630 C  CB    . ASN   B 1 45  ? -6.419  14.621  -12.485 1.000 89.119  0 45  ASN   B CB    1 ? 
ATOM   1631 C  CG    . ASN   B 1 45  ? -6.968  13.239  -12.747 1.000 88.304  0 45  ASN   B CG    1 ? 
ATOM   1632 O  OD1   . ASN   B 1 45  ? -6.376  12.455  -13.497 1.000 85.137  0 45  ASN   B OD1   1 ? 
ATOM   1633 N  ND2   . ASN   B 1 45  ? -8.155  12.950  -12.236 1.000 92.049  0 45  ASN   B ND2   1 ? 
ATOM   1634 N  N     . GLN   B 1 46  ? -7.079  18.016  -13.923 1.000 101.888 0 46  GLN   B N     1 ? 
ATOM   1635 C  CA    . GLN   B 1 46  ? -6.848  19.437  -13.731 1.000 94.842  0 46  GLN   B CA    1 ? 
ATOM   1636 C  C     . GLN   B 1 46  ? -7.928  19.968  -12.794 1.000 77.066  0 46  GLN   B C     1 ? 
ATOM   1637 O  O     . GLN   B 1 46  ? -9.094  19.657  -13.001 1.000 85.551  0 46  GLN   B O     1 ? 
ATOM   1638 C  CB    . GLN   B 1 46  ? -6.926  20.176  -15.070 1.000 108.733 0 46  GLN   B CB    1 ? 
ATOM   1639 C  CG    . GLN   B 1 46  ? -6.154  19.537  -16.229 1.000 111.496 0 46  GLN   B CG    1 ? 
ATOM   1640 C  CD    . GLN   B 1 46  ? -6.105  20.394  -17.482 1.000 118.914 0 46  GLN   B CD    1 ? 
ATOM   1641 O  OE1   . GLN   B 1 46  ? -6.898  20.208  -18.410 1.000 117.150 0 46  GLN   B OE1   1 ? 
ATOM   1642 N  NE2   . GLN   B 1 46  ? -5.189  21.355  -17.534 1.000 120.636 0 46  GLN   B NE2   1 ? 
ATOM   1643 N  N     . TYR   B 1 47  ? -7.550  20.763  -11.783 1.000 76.530  0 47  TYR   B N     1 ? 
ATOM   1644 C  CA    . TYR   B 1 47  ? -8.482  21.071  -10.706 1.000 77.268  0 47  TYR   B CA    1 ? 
ATOM   1645 C  C     . TYR   B 1 47  ? -9.682  21.813  -11.296 1.000 78.527  0 47  TYR   B C     1 ? 
ATOM   1646 O  O     . TYR   B 1 47  ? -9.490  22.839  -11.947 1.000 71.011  0 47  TYR   B O     1 ? 
ATOM   1647 C  CB    . TYR   B 1 47  ? -7.890  21.916  -9.564  1.000 73.096  0 47  TYR   B CB    1 ? 
ATOM   1648 C  CG    . TYR   B 1 47  ? -8.834  22.185  -8.386  1.000 65.944  0 47  TYR   B CG    1 ? 
ATOM   1649 C  CD1   . TYR   B 1 47  ? -9.469  21.129  -7.711  1.000 75.373  0 47  TYR   B CD1   1 ? 
ATOM   1650 C  CD2   . TYR   B 1 47  ? -9.116  23.488  -7.967  1.000 59.611  0 47  TYR   B CD2   1 ? 
ATOM   1651 C  CE1   . TYR   B 1 47  ? -10.350 21.366  -6.663  1.000 68.339  0 47  TYR   B CE1   1 ? 
ATOM   1652 C  CE2   . TYR   B 1 47  ? -9.986  23.733  -6.910  1.000 69.817  0 47  TYR   B CE2   1 ? 
ATOM   1653 C  CZ    . TYR   B 1 47  ? -10.594 22.670  -6.251  1.000 66.256  0 47  TYR   B CZ    1 ? 
ATOM   1654 O  OH    . TYR   B 1 47  ? -11.468 22.911  -5.225  1.000 86.687  0 47  TYR   B OH    1 ? 
ATOM   1655 N  N     . LYS   B 1 48  ? -10.888 21.277  -11.036 1.000 80.895  0 48  LYS   B N     1 ? 
ATOM   1656 C  CA    . LYS   B 1 48  ? -12.170 21.911  -11.331 1.000 97.989  0 48  LYS   B CA    1 ? 
ATOM   1657 C  C     . LYS   B 1 48  ? -12.410 22.052  -12.842 1.000 109.144 0 48  LYS   B C     1 ? 
ATOM   1658 O  O     . LYS   B 1 48  ? -13.306 22.792  -13.234 1.000 111.508 0 48  LYS   B O     1 ? 
ATOM   1659 C  CB    . LYS   B 1 48  ? -12.324 23.246  -10.579 1.000 94.315  0 48  LYS   B CB    1 ? 
ATOM   1660 C  CG    . LYS   B 1 48  ? -13.056 23.118  -9.222  1.000 102.711 0 48  LYS   B CG    1 ? 
ATOM   1661 C  CD    . LYS   B 1 48  ? -13.321 24.405  -8.443  1.000 100.650 0 48  LYS   B CD    1 ? 
ATOM   1662 N  N     . GLY   B 1 49  ? -11.633 21.351  -13.688 1.000 118.966 0 49  GLY   B N     1 ? 
ATOM   1663 C  CA    . GLY   B 1 49  ? -11.783 21.424  -15.134 1.000 115.781 0 49  GLY   B CA    1 ? 
ATOM   1664 C  C     . GLY   B 1 49  ? -11.133 22.662  -15.759 1.000 120.463 0 49  GLY   B C     1 ? 
ATOM   1665 O  O     . GLY   B 1 49  ? -11.221 22.860  -16.967 1.000 132.443 0 49  GLY   B O     1 ? 
ATOM   1666 N  N     . ILE   B 1 50  ? -10.450 23.495  -14.964 1.000 120.534 0 50  ILE   B N     1 ? 
ATOM   1667 C  CA    . ILE   B 1 50  ? -9.957  24.766  -15.481 1.000 124.376 0 50  ILE   B CA    1 ? 
ATOM   1668 C  C     . ILE   B 1 50  ? -8.637  24.523  -16.225 1.000 113.867 0 50  ILE   B C     1 ? 
ATOM   1669 O  O     . ILE   B 1 50  ? -7.814  23.714  -15.803 1.000 86.478  0 50  ILE   B O     1 ? 
ATOM   1670 C  CB    . ILE   B 1 50  ? -9.858  25.839  -14.371 1.000 118.890 0 50  ILE   B CB    1 ? 
ATOM   1671 C  CG1   . ILE   B 1 50  ? -8.514  25.837  -13.643 1.000 122.626 0 50  ILE   B CG1   1 ? 
ATOM   1672 C  CG2   . ILE   B 1 50  ? -11.025 25.735  -13.383 1.000 118.392 0 50  ILE   B CG2   1 ? 
ATOM   1673 C  CD1   . ILE   B 1 50  ? -7.423  26.628  -14.348 1.000 125.447 0 50  ILE   B CD1   1 ? 
ATOM   1674 N  N     . ARG   B 1 51  ? -8.430  25.237  -17.339 1.000 117.724 0 51  ARG   B N     1 ? 
ATOM   1675 C  CA    . ARG   B 1 51  ? -7.290  24.971  -18.202 1.000 118.146 0 51  ARG   B CA    1 ? 
ATOM   1676 C  C     . ARG   B 1 51  ? -6.234  26.064  -18.009 1.000 127.445 0 51  ARG   B C     1 ? 
ATOM   1677 O  O     . ARG   B 1 51  ? -6.316  27.155  -18.566 1.000 123.735 0 51  ARG   B O     1 ? 
ATOM   1678 C  CB    . ARG   B 1 51  ? -7.798  24.741  -19.629 1.000 106.732 0 51  ARG   B CB    1 ? 
ATOM   1679 N  N     . VAL   B 1 52  ? -5.212  25.725  -17.215 1.000 129.884 0 52  VAL   B N     1 ? 
ATOM   1680 C  CA    . VAL   B 1 52  ? -4.076  26.591  -16.933 1.000 125.488 0 52  VAL   B CA    1 ? 
ATOM   1681 C  C     . VAL   B 1 52  ? -3.526  27.271  -18.195 1.000 121.413 0 52  VAL   B C     1 ? 
ATOM   1682 O  O     . VAL   B 1 52  ? -2.827  28.284  -18.100 1.000 108.614 0 52  VAL   B O     1 ? 
ATOM   1683 C  CB    . VAL   B 1 52  ? -3.016  25.701  -16.251 1.000 125.193 0 52  VAL   B CB    1 ? 
ATOM   1684 C  CG1   . VAL   B 1 52  ? -2.765  24.403  -17.025 1.000 115.563 0 52  VAL   B CG1   1 ? 
ATOM   1685 C  CG2   . VAL   B 1 52  ? -1.713  26.451  -16.013 1.000 129.317 0 52  VAL   B CG2   1 ? 
ATOM   1686 N  N     . ASP   B 1 53  ? -3.795  26.695  -19.377 1.000 133.833 0 53  ASP   B N     1 ? 
ATOM   1687 C  CA    . ASP   B 1 53  ? -3.322  27.259  -20.636 1.000 120.284 0 53  ASP   B CA    1 ? 
ATOM   1688 C  C     . ASP   B 1 53  ? -4.275  28.357  -21.109 1.000 108.136 0 53  ASP   B C     1 ? 
ATOM   1689 O  O     . ASP   B 1 53  ? -3.817  29.416  -21.548 1.000 89.452  0 53  ASP   B O     1 ? 
ATOM   1690 C  CB    . ASP   B 1 53  ? -3.021  26.221  -21.718 1.000 116.715 0 53  ASP   B CB    1 ? 
ATOM   1691 C  CG    . ASP   B 1 53  ? -3.656  24.837  -21.603 1.000 121.273 0 53  ASP   B CG    1 ? 
ATOM   1692 O  OD1   . ASP   B 1 53  ? -3.099  23.998  -20.852 1.000 136.319 0 53  ASP   B OD1   1 ? 
ATOM   1693 O  OD2   . ASP   B 1 53  ? -4.703  24.598  -22.252 1.000 93.805  0 53  ASP   B OD2   1 ? 
ATOM   1694 N  N     . GLU   B 1 54  ? -5.592  28.106  -20.989 1.000 107.920 0 54  GLU   B N     1 ? 
ATOM   1695 C  CA    . GLU   B 1 54  ? -6.620  29.035  -21.442 1.000 118.197 0 54  GLU   B CA    1 ? 
ATOM   1696 C  C     . GLU   B 1 54  ? -6.891  30.138  -20.408 1.000 130.578 0 54  GLU   B C     1 ? 
ATOM   1697 O  O     . GLU   B 1 54  ? -7.521  31.137  -20.758 1.000 110.025 0 54  GLU   B O     1 ? 
ATOM   1698 C  CB    . GLU   B 1 54  ? -7.891  28.256  -21.798 1.000 110.338 0 54  GLU   B CB    1 ? 
ATOM   1699 N  N     . HIS   B 1 55  ? -6.433  29.963  -19.148 1.000 133.829 0 55  HIS   B N     1 ? 
ATOM   1700 C  CA    . HIS   B 1 55  ? -6.615  30.967  -18.107 1.000 111.653 0 55  HIS   B CA    1 ? 
ATOM   1701 C  C     . HIS   B 1 55  ? -5.389  31.050  -17.192 1.000 106.192 0 55  HIS   B C     1 ? 
ATOM   1702 O  O     . HIS   B 1 55  ? -5.459  30.669  -16.026 1.000 96.293  0 55  HIS   B O     1 ? 
ATOM   1703 C  CB    . HIS   B 1 55  ? -7.853  30.672  -17.247 1.000 124.241 0 55  HIS   B CB    1 ? 
ATOM   1704 C  CG    . HIS   B 1 55  ? -9.168  30.513  -17.957 1.000 137.786 0 55  HIS   B CG    1 ? 
ATOM   1705 N  ND1   . HIS   B 1 55  ? -9.990  31.573  -18.285 1.000 127.344 0 55  HIS   B ND1   1 ? 
ATOM   1706 C  CD2   . HIS   B 1 55  ? -9.817  29.403  -18.356 1.000 129.728 0 55  HIS   B CD2   1 ? 
ATOM   1707 C  CE1   . HIS   B 1 55  ? -11.082 31.116  -18.877 1.000 125.669 0 55  HIS   B CE1   1 ? 
ATOM   1708 N  NE2   . HIS   B 1 55  ? -11.001 29.800  -18.925 1.000 131.325 0 55  HIS   B NE2   1 ? 
ATOM   1709 N  N     . PRO   B 1 56  ? -4.242  31.600  -17.656 1.000 101.415 0 56  PRO   B N     1 ? 
ATOM   1710 C  CA    . PRO   B 1 56  ? -2.997  31.613  -16.866 1.000 97.068  0 56  PRO   B CA    1 ? 
ATOM   1711 C  C     . PRO   B 1 56  ? -2.934  32.544  -15.651 1.000 99.765  0 56  PRO   B C     1 ? 
ATOM   1712 O  O     . PRO   B 1 56  ? -1.865  32.730  -15.053 1.000 82.554  0 56  PRO   B O     1 ? 
ATOM   1713 C  CB    . PRO   B 1 56  ? -1.948  32.038  -17.908 1.000 99.197  0 56  PRO   B CB    1 ? 
ATOM   1714 C  CG    . PRO   B 1 56  ? -2.730  32.928  -18.848 1.000 105.093 0 56  PRO   B CG    1 ? 
ATOM   1715 C  CD    . PRO   B 1 56  ? -4.091  32.242  -18.971 1.000 108.966 0 56  PRO   B CD    1 ? 
ATOM   1716 N  N     . GLU   B 1 57  ? -4.071  33.176  -15.339 1.000 96.424  0 57  GLU   B N     1 ? 
ATOM   1717 C  CA    . GLU   B 1 57  ? -4.196  33.957  -14.122 1.000 93.467  0 57  GLU   B CA    1 ? 
ATOM   1718 C  C     . GLU   B 1 57  ? -4.230  33.013  -12.917 1.000 82.220  0 57  GLU   B C     1 ? 
ATOM   1719 O  O     . GLU   B 1 57  ? -3.844  33.421  -11.831 1.000 74.750  0 57  GLU   B O     1 ? 
ATOM   1720 C  CB    . GLU   B 1 57  ? -5.372  34.943  -14.150 1.000 100.802 0 57  GLU   B CB    1 ? 
ATOM   1721 C  CG    . GLU   B 1 57  ? -6.770  34.319  -14.220 1.000 111.696 0 57  GLU   B CG    1 ? 
ATOM   1722 C  CD    . GLU   B 1 57  ? -7.345  34.045  -15.607 1.000 109.258 0 57  GLU   B CD    1 ? 
ATOM   1723 O  OE1   . GLU   B 1 57  ? -6.573  34.024  -16.594 1.000 88.655  0 57  GLU   B OE1   1 ? 
ATOM   1724 O  OE2   . GLU   B 1 57  ? -8.582  33.869  -15.691 1.000 103.358 0 57  GLU   B OE2   1 ? 
ATOM   1725 N  N     . TYR   B 1 58  ? -4.606  31.740  -13.108 1.000 80.191  0 58  TYR   B N     1 ? 
ATOM   1726 C  CA    . TYR   B 1 58  ? -4.727  30.801  -12.000 1.000 73.366  0 58  TYR   B CA    1 ? 
ATOM   1727 C  C     . TYR   B 1 58  ? -3.363  30.392  -11.427 1.000 74.522  0 58  TYR   B C     1 ? 
ATOM   1728 O  O     . TYR   B 1 58  ? -3.324  29.761  -10.371 1.000 70.707  0 58  TYR   B O     1 ? 
ATOM   1729 C  CB    . TYR   B 1 58  ? -5.602  29.617  -12.422 1.000 74.768  0 58  TYR   B CB    1 ? 
ATOM   1730 C  CG    . TYR   B 1 58  ? -7.093  29.938  -12.369 1.000 92.038  0 58  TYR   B CG    1 ? 
ATOM   1731 C  CD1   . TYR   B 1 58  ? -7.726  30.612  -13.409 1.000 101.131 0 58  TYR   B CD1   1 ? 
ATOM   1732 C  CD2   . TYR   B 1 58  ? -7.868  29.589  -11.265 1.000 106.049 0 58  TYR   B CD2   1 ? 
ATOM   1733 C  CE1   . TYR   B 1 58  ? -9.072  30.934  -13.353 1.000 102.716 0 58  TYR   B CE1   1 ? 
ATOM   1734 C  CE2   . TYR   B 1 58  ? -9.220  29.888  -11.205 1.000 109.850 0 58  TYR   B CE2   1 ? 
ATOM   1735 C  CZ    . TYR   B 1 58  ? -9.822  30.566  -12.251 1.000 111.395 0 58  TYR   B CZ    1 ? 
ATOM   1736 O  OH    . TYR   B 1 58  ? -11.148 30.878  -12.184 1.000 103.195 0 58  TYR   B OH    1 ? 
ATOM   1737 N  N     . LEU   B 1 59  ? -2.264  30.864  -12.036 1.000 67.935  0 59  LEU   B N     1 ? 
ATOM   1738 C  CA    . LEU   B 1 59  ? -0.911  30.577  -11.589 1.000 79.245  0 59  LEU   B CA    1 ? 
ATOM   1739 C  C     . LEU   B 1 59  ? -0.452  31.564  -10.508 1.000 90.056  0 59  LEU   B C     1 ? 
ATOM   1740 O  O     . LEU   B 1 59  ? 0.714   31.559  -10.077 1.000 79.251  0 59  LEU   B O     1 ? 
ATOM   1741 C  CB    . LEU   B 1 59  ? -0.040  30.631  -12.843 1.000 83.617  0 59  LEU   B CB    1 ? 
ATOM   1742 C  CG    . LEU   B 1 59  ? -0.374  29.615  -13.951 1.000 89.527  0 59  LEU   B CG    1 ? 
ATOM   1743 C  CD1   . LEU   B 1 59  ? 0.542   29.833  -15.166 1.000 87.298  0 59  LEU   B CD1   1 ? 
ATOM   1744 C  CD2   . LEU   B 1 59  ? -0.304  28.157  -13.477 1.000 82.847  0 59  LEU   B CD2   1 ? 
ATOM   1745 N  N     . HIS   B 1 60  ? -1.380  32.425  -10.079 1.000 75.340  0 60  HIS   B N     1 ? 
ATOM   1746 C  CA    . HIS   B 1 60  ? -1.184  33.257  -8.897  1.000 78.374  0 60  HIS   B CA    1 ? 
ATOM   1747 C  C     . HIS   B 1 60  ? -2.198  32.875  -7.807  1.000 66.004  0 60  HIS   B C     1 ? 
ATOM   1748 O  O     . HIS   B 1 60  ? -2.071  33.319  -6.676  1.000 69.739  0 60  HIS   B O     1 ? 
ATOM   1749 C  CB    . HIS   B 1 60  ? -1.192  34.752  -9.281  1.000 84.057  0 60  HIS   B CB    1 ? 
ATOM   1750 C  CG    . HIS   B 1 60  ? 0.045   35.282  -9.980  1.000 76.663  0 60  HIS   B CG    1 ? 
ATOM   1751 N  ND1   . HIS   B 1 60  ? 1.122   35.859  -9.324  1.000 86.336  0 60  HIS   B ND1   1 ? 
ATOM   1752 C  CD2   . HIS   B 1 60  ? 0.358   35.337  -11.294 1.000 78.571  0 60  HIS   B CD2   1 ? 
ATOM   1753 C  CE1   . HIS   B 1 60  ? 2.057   36.219  -10.206 1.000 71.128  0 60  HIS   B CE1   1 ? 
ATOM   1754 N  NE2   . HIS   B 1 60  ? 1.615   35.902  -11.411 1.000 78.180  0 60  HIS   B NE2   1 ? 
ATOM   1755 N  N     . ASP   B 1 61  ? -3.185  32.025  -8.152  1.000 60.778  0 61  ASP   B N     1 ? 
ATOM   1756 C  CA    . ASP   B 1 61  ? -4.201  31.540  -7.232  1.000 60.652  0 61  ASP   B CA    1 ? 
ATOM   1757 C  C     . ASP   B 1 61  ? -3.574  30.433  -6.377  1.000 66.106  0 61  ASP   B C     1 ? 
ATOM   1758 O  O     . ASP   B 1 61  ? -3.117  29.420  -6.894  1.000 62.924  0 61  ASP   B O     1 ? 
ATOM   1759 C  CB    . ASP   B 1 61  ? -5.471  31.156  -7.978  1.000 58.710  0 61  ASP   B CB    1 ? 
ATOM   1760 C  CG    . ASP   B 1 61  ? -6.599  30.564  -7.145  1.000 59.818  0 61  ASP   B CG    1 ? 
ATOM   1761 O  OD1   . ASP   B 1 61  ? -6.423  30.388  -5.938  1.000 73.252  0 61  ASP   B OD1   1 ? 
ATOM   1762 O  OD2   . ASP   B 1 61  ? -7.647  30.250  -7.716  1.000 72.725  0 61  ASP   B OD2   1 ? 
ATOM   1763 N  N     . LYS   B 1 62  ? -3.548  30.650  -5.055  1.000 58.018  0 62  LYS   B N     1 ? 
ATOM   1764 C  CA    . LYS   B 1 62  ? -2.934  29.726  -4.107  1.000 58.938  0 62  LYS   B CA    1 ? 
ATOM   1765 C  C     . LYS   B 1 62  ? -3.829  28.522  -3.835  1.000 53.122  0 62  LYS   B C     1 ? 
ATOM   1766 O  O     . LYS   B 1 62  ? -3.340  27.461  -3.459  1.000 57.187  0 62  LYS   B O     1 ? 
ATOM   1767 C  CB    . LYS   B 1 62  ? -2.630  30.444  -2.791  1.000 53.216  0 62  LYS   B CB    1 ? 
ATOM   1768 C  CG    . LYS   B 1 62  ? -1.594  31.553  -2.933  1.000 54.778  0 62  LYS   B CG    1 ? 
ATOM   1769 C  CD    . LYS   B 1 62  ? -1.394  32.282  -1.607  1.000 57.141  0 62  LYS   B CD    1 ? 
ATOM   1770 C  CE    . LYS   B 1 62  ? -0.156  33.113  -1.559  1.000 58.694  0 62  LYS   B CE    1 ? 
ATOM   1771 N  NZ    . LYS   B 1 62  ? -0.282  34.399  -2.239  1.000 60.754  0 62  LYS   B NZ    1 ? 
ATOM   1772 N  N     . VAL   B 1 63  ? -5.140  28.699  -4.024  1.000 55.682  0 63  VAL   B N     1 ? 
ATOM   1773 C  CA    . VAL   B 1 63  ? -6.085  27.608  -3.871  1.000 51.403  0 63  VAL   B CA    1 ? 
ATOM   1774 C  C     . VAL   B 1 63  ? -5.931  26.640  -5.044  1.000 56.798  0 63  VAL   B C     1 ? 
ATOM   1775 O  O     . VAL   B 1 63  ? -5.873  25.431  -4.850  1.000 61.575  0 63  VAL   B O     1 ? 
ATOM   1776 C  CB    . VAL   B 1 63  ? -7.511  28.165  -3.772  1.000 55.320  0 63  VAL   B CB    1 ? 
ATOM   1777 C  CG1   . VAL   B 1 63  ? -8.564  27.060  -3.752  1.000 61.176  0 63  VAL   B CG1   1 ? 
ATOM   1778 C  CG2   . VAL   B 1 63  ? -7.665  29.085  -2.570  1.000 61.344  0 63  VAL   B CG2   1 ? 
ATOM   1779 N  N     . TRP   B 1 64  ? -5.888  27.167  -6.269  1.000 59.337  0 64  TRP   B N     1 ? 
ATOM   1780 C  CA    . TRP   B 1 64  ? -5.638  26.325  -7.429  1.000 57.913  0 64  TRP   B CA    1 ? 
ATOM   1781 C  C     . TRP   B 1 64  ? -4.366  25.505  -7.209  1.000 55.472  0 64  TRP   B C     1 ? 
ATOM   1782 O  O     . TRP   B 1 64  ? -4.382  24.295  -7.420  1.000 48.255  0 64  TRP   B O     1 ? 
ATOM   1783 C  CB    . TRP   B 1 64  ? -5.542  27.137  -8.736  1.000 57.838  0 64  TRP   B CB    1 ? 
ATOM   1784 C  CG    . TRP   B 1 64  ? -5.232  26.262  -9.922  1.000 57.735  0 64  TRP   B CG    1 ? 
ATOM   1785 C  CD1   . TRP   B 1 64  ? -6.132  25.552  -10.671 1.000 55.558  0 64  TRP   B CD1   1 ? 
ATOM   1786 C  CD2   . TRP   B 1 64  ? -3.925  25.883  -10.401 1.000 55.545  0 64  TRP   B CD2   1 ? 
ATOM   1787 N  NE1   . TRP   B 1 64  ? -5.484  24.806  -11.616 1.000 57.583  0 64  TRP   B NE1   1 ? 
ATOM   1788 C  CE2   . TRP   B 1 64  ? -4.132  24.979  -11.465 1.000 59.768  0 64  TRP   B CE2   1 ? 
ATOM   1789 C  CE3   . TRP   B 1 64  ? -2.620  26.218  -10.040 1.000 60.548  0 64  TRP   B CE3   1 ? 
ATOM   1790 C  CZ2   . TRP   B 1 64  ? -3.073  24.415  -12.162 1.000 56.906  0 64  TRP   B CZ2   1 ? 
ATOM   1791 C  CZ3   . TRP   B 1 64  ? -1.572  25.634  -10.709 1.000 58.947  0 64  TRP   B CZ3   1 ? 
ATOM   1792 C  CH2   . TRP   B 1 64  ? -1.801  24.728  -11.740 1.000 58.024  0 64  TRP   B CH2   1 ? 
ATOM   1793 N  N     . ALA   B 1 65  ? -3.274  26.175  -6.789  1.000 48.095  0 65  ALA   B N     1 ? 
ATOM   1794 C  CA    . ALA   B 1 65  ? -1.977  25.526  -6.605  1.000 47.890  0 65  ALA   B CA    1 ? 
ATOM   1795 C  C     . ALA   B 1 65  ? -2.021  24.472  -5.497  1.000 54.484  0 65  ALA   B C     1 ? 
ATOM   1796 O  O     . ALA   B 1 65  ? -1.496  23.376  -5.682  1.000 49.721  0 65  ALA   B O     1 ? 
ATOM   1797 C  CB    . ALA   B 1 65  ? -0.932  26.577  -6.312  1.000 46.451  0 65  ALA   B CB    1 ? 
ATOM   1798 N  N     . THR   B 1 66  ? -2.687  24.806  -4.372  1.000 51.648  0 66  THR   B N     1 ? 
ATOM   1799 C  CA    . THR   B 1 66  ? -2.849  23.885  -3.263  1.000 51.644  0 66  THR   B CA    1 ? 
ATOM   1800 C  C     . THR   B 1 66  ? -3.548  22.621  -3.751  1.000 52.297  0 66  THR   B C     1 ? 
ATOM   1801 O  O     . THR   B 1 66  ? -3.052  21.522  -3.512  1.000 51.297  0 66  THR   B O     1 ? 
ATOM   1802 C  CB    . THR   B 1 66  ? -3.592  24.531  -2.089  1.000 49.688  0 66  THR   B CB    1 ? 
ATOM   1803 O  OG1   . THR   B 1 66  ? -2.737  25.529  -1.552  1.000 45.099  0 66  THR   B OG1   1 ? 
ATOM   1804 C  CG2   . THR   B 1 66  ? -3.848  23.559  -0.951  1.000 48.273  0 66  THR   B CG2   1 ? 
ATOM   1805 N  N     . ALA   B 1 67  ? -4.690  22.781  -4.427  1.000 51.301  0 67  ALA   B N     1 ? 
ATOM   1806 C  CA    . ALA   B 1 67  ? -5.504  21.646  -4.851  1.000 53.362  0 67  ALA   B CA    1 ? 
ATOM   1807 C  C     . ALA   B 1 67  ? -4.776  20.794  -5.886  1.000 48.578  0 67  ALA   B C     1 ? 
ATOM   1808 O  O     . ALA   B 1 67  ? -4.886  19.571  -5.870  1.000 52.818  0 67  ALA   B O     1 ? 
ATOM   1809 C  CB    . ALA   B 1 67  ? -6.833  22.116  -5.415  1.000 54.886  0 67  ALA   B CB    1 ? 
ATOM   1810 N  N     . THR   B 1 68  ? -4.038  21.441  -6.779  1.000 48.946  0 68  THR   B N     1 ? 
ATOM   1811 C  CA    . THR   B 1 68  ? -3.370  20.713  -7.848  1.000 55.779  0 68  THR   B CA    1 ? 
ATOM   1812 C  C     . THR   B 1 68  ? -2.184  19.945  -7.275  1.000 48.151  0 68  THR   B C     1 ? 
ATOM   1813 O  O     . THR   B 1 68  ? -1.976  18.780  -7.597  1.000 54.727  0 68  THR   B O     1 ? 
ATOM   1814 C  CB    . THR   B 1 68  ? -2.935  21.663  -8.971  1.000 51.526  0 68  THR   B CB    1 ? 
ATOM   1815 O  OG1   . THR   B 1 68  ? -4.098  22.349  -9.399  1.000 45.737  0 68  THR   B OG1   1 ? 
ATOM   1816 C  CG2   . THR   B 1 68  ? -2.390  20.920  -10.172 1.000 51.746  0 68  THR   B CG2   1 ? 
ATOM   1817 N  N     . TYR   B 1 69  ? -1.380  20.608  -6.444  1.000 57.096  0 69  TYR   B N     1 ? 
ATOM   1818 C  CA    . TYR   B 1 69  ? -0.275  19.937  -5.768  1.000 52.835  0 69  TYR   B CA    1 ? 
ATOM   1819 C  C     . TYR   B 1 69  ? -0.810  18.734  -5.005  1.000 50.906  0 69  TYR   B C     1 ? 
ATOM   1820 O  O     . TYR   B 1 69  ? -0.309  17.638  -5.173  1.000 55.078  0 69  TYR   B O     1 ? 
ATOM   1821 C  CB    . TYR   B 1 69  ? 0.485   20.910  -4.860  1.000 51.574  0 69  TYR   B CB    1 ? 
ATOM   1822 C  CG    . TYR   B 1 69  ? 1.554   20.291  -3.964  1.000 48.799  0 69  TYR   B CG    1 ? 
ATOM   1823 C  CD1   . TYR   B 1 69  ? 2.774   19.895  -4.481  1.000 49.834  0 69  TYR   B CD1   1 ? 
ATOM   1824 C  CD2   . TYR   B 1 69  ? 1.365   20.158  -2.586  1.000 51.782  0 69  TYR   B CD2   1 ? 
ATOM   1825 C  CE1   . TYR   B 1 69  ? 3.776   19.382  -3.672  1.000 47.052  0 69  TYR   B CE1   1 ? 
ATOM   1826 C  CE2   . TYR   B 1 69  ? 2.348   19.628  -1.768  1.000 51.032  0 69  TYR   B CE2   1 ? 
ATOM   1827 C  CZ    . TYR   B 1 69  ? 3.550   19.222  -2.317  1.000 49.706  0 69  TYR   B CZ    1 ? 
ATOM   1828 O  OH    . TYR   B 1 69  ? 4.537   18.712  -1.536  1.000 46.885  0 69  TYR   B OH    1 ? 
ATOM   1829 N  N     . ASN   B 1 70  ? -1.875  18.924  -4.223  1.000 51.310  0 70  ASN   B N     1 ? 
ATOM   1830 C  CA    . ASN   B 1 70  ? -2.393  17.851  -3.394  1.000 46.943  0 70  ASN   B CA    1 ? 
ATOM   1831 C  C     . ASN   B 1 70  ? -2.976  16.721  -4.238  1.000 53.940  0 70  ASN   B C     1 ? 
ATOM   1832 O  O     . ASN   B 1 70  ? -2.887  15.554  -3.850  1.000 50.750  0 70  ASN   B O     1 ? 
ATOM   1833 C  CB    . ASN   B 1 70  ? -3.346  18.419  -2.350  1.000 53.290  0 70  ASN   B CB    1 ? 
ATOM   1834 C  CG    . ASN   B 1 70  ? -2.548  19.034  -1.226  1.000 56.196  0 70  ASN   B CG    1 ? 
ATOM   1835 O  OD1   . ASN   B 1 70  ? -1.764  18.355  -0.569  1.000 67.445  0 70  ASN   B OD1   1 ? 
ATOM   1836 N  ND2   . ASN   B 1 70  ? -2.696  20.315  -0.994  1.000 61.249  0 70  ASN   B ND2   1 ? 
ATOM   1837 N  N     . ASN   B 1 71  ? -3.577  17.048  -5.386  1.000 53.737  0 71  ASN   B N     1 ? 
ATOM   1838 C  CA    . ASN   B 1 71  ? -4.115  16.019  -6.269  1.000 57.827  0 71  ASN   B CA    1 ? 
ATOM   1839 C  C     . ASN   B 1 71  ? -2.998  15.107  -6.769  1.000 48.731  0 71  ASN   B C     1 ? 
ATOM   1840 O  O     . ASN   B 1 71  ? -3.164  13.893  -6.821  1.000 53.472  0 71  ASN   B O     1 ? 
ATOM   1841 C  CB    . ASN   B 1 71  ? -4.924  16.627  -7.411  1.000 61.143  0 71  ASN   B CB    1 ? 
ATOM   1842 C  CG    . ASN   B 1 71  ? -6.398  16.492  -7.161  1.000 63.349  0 71  ASN   B CG    1 ? 
ATOM   1843 O  OD1   . ASN   B 1 71  ? -7.079  17.496  -6.915  1.000 73.850  0 71  ASN   B OD1   1 ? 
ATOM   1844 N  ND2   . ASN   B 1 71  ? -6.858  15.251  -7.103  1.000 58.739  0 71  ASN   B ND2   1 ? 
ATOM   1845 N  N     . ASP   B 1 72  ? -1.861  15.703  -7.138  1.000 52.369  0 72  ASP   B N     1 ? 
ATOM   1846 C  CA    . ASP   B 1 72  ? -0.723  14.944  -7.617  1.000 45.097  0 72  ASP   B CA    1 ? 
ATOM   1847 C  C     . ASP   B 1 72  ? -0.188  14.045  -6.512  1.000 51.079  0 72  ASP   B C     1 ? 
ATOM   1848 O  O     . ASP   B 1 72  ? 0.038   12.861  -6.741  1.000 50.604  0 72  ASP   B O     1 ? 
ATOM   1849 C  CB    . ASP   B 1 72  ? 0.336   15.874  -8.162  1.000 51.702  0 72  ASP   B CB    1 ? 
ATOM   1850 C  CG    . ASP   B 1 72  ? 0.028   16.457  -9.533  1.000 60.800  0 72  ASP   B CG    1 ? 
ATOM   1851 O  OD1   . ASP   B 1 72  ? -1.067  16.160  -10.083 1.000 68.375  0 72  ASP   B OD1   1 ? 
ATOM   1852 O  OD2   . ASP   B 1 72  ? 0.920   17.152  -10.059 1.000 75.557  0 72  ASP   B OD2   1 ? 
ATOM   1853 N  N     . LEU   B 1 73  ? -0.002  14.603  -5.297  1.000 48.278  0 73  LEU   B N     1 ? 
ATOM   1854 C  CA    . LEU   B 1 73  ? 0.495   13.798  -4.201  1.000 50.021  0 73  LEU   B CA    1 ? 
ATOM   1855 C  C     . LEU   B 1 73  ? -0.469  12.636  -3.979  1.000 52.327  0 73  LEU   B C     1 ? 
ATOM   1856 O  O     . LEU   B 1 73  ? -0.056  11.487  -3.821  1.000 45.095  0 73  LEU   B O     1 ? 
ATOM   1857 C  CB    . LEU   B 1 73  ? 0.672   14.598  -2.914  1.000 54.256  0 73  LEU   B CB    1 ? 
ATOM   1858 C  CG    . LEU   B 1 73  ? 1.731   15.703  -2.935  1.000 53.813  0 73  LEU   B CG    1 ? 
ATOM   1859 C  CD1   . LEU   B 1 73  ? 2.142   16.045  -1.508  1.000 58.978  0 73  LEU   B CD1   1 ? 
ATOM   1860 C  CD2   . LEU   B 1 73  ? 2.941   15.416  -3.734  1.000 55.682  0 73  LEU   B CD2   1 ? 
ATOM   1861 N  N     . ASN   B 1 74  ? -1.761  12.956  -3.968  1.000 50.987  0 74  ASN   B N     1 ? 
ATOM   1862 C  CA    . ASN   B 1 74  ? -2.799  11.955  -3.797  1.000 50.444  0 74  ASN   B CA    1 ? 
ATOM   1863 C  C     . ASN   B 1 74  ? -2.761  10.891  -4.897  1.000 47.659  0 74  ASN   B C     1 ? 
ATOM   1864 O  O     . ASN   B 1 74  ? -2.925  9.694   -4.640  1.000 48.634  0 74  ASN   B O     1 ? 
ATOM   1865 C  CB    . ASN   B 1 74  ? -4.139  12.660  -3.806  1.000 54.561  0 74  ASN   B CB    1 ? 
ATOM   1866 C  CG    . ASN   B 1 74  ? -5.234  11.690  -3.490  1.000 59.343  0 74  ASN   B CG    1 ? 
ATOM   1867 O  OD1   . ASN   B 1 74  ? -6.056  11.404  -4.363  1.000 69.602  0 74  ASN   B OD1   1 ? 
ATOM   1868 N  ND2   . ASN   B 1 74  ? -5.252  11.197  -2.264  1.000 54.179  0 74  ASN   B ND2   1 ? 
ATOM   1869 N  N     . GLY   B 1 75  ? -2.540  11.327  -6.135  1.000 46.631  0 75  GLY   B N     1 ? 
ATOM   1870 C  CA    . GLY   B 1 75  ? -2.413  10.400  -7.254  1.000 48.082  0 75  GLY   B CA    1 ? 
ATOM   1871 C  C     . GLY   B 1 75  ? -1.221  9.471   -7.068  1.000 51.386  0 75  GLY   B C     1 ? 
ATOM   1872 O  O     . GLY   B 1 75  ? -1.268  8.300   -7.444  1.000 53.282  0 75  GLY   B O     1 ? 
ATOM   1873 N  N     . ILE   B 1 76  ? -0.133  9.970   -6.464  1.000 56.333  0 76  ILE   B N     1 ? 
ATOM   1874 C  CA    . ILE   B 1 76  ? 1.004   9.093   -6.226  1.000 53.187  0 76  ILE   B CA    1 ? 
ATOM   1875 C  C     . ILE   B 1 76  ? 0.686   8.111   -5.107  1.000 45.417  0 76  ILE   B C     1 ? 
ATOM   1876 O  O     . ILE   B 1 76  ? 0.878   6.895   -5.250  1.000 45.945  0 76  ILE   B O     1 ? 
ATOM   1877 C  CB    . ILE   B 1 76  ? 2.279   9.881   -5.924  1.000 57.117  0 76  ILE   B CB    1 ? 
ATOM   1878 C  CG1   . ILE   B 1 76  ? 2.678   10.742  -7.112  1.000 56.727  0 76  ILE   B CG1   1 ? 
ATOM   1879 C  CG2   . ILE   B 1 76  ? 3.371   8.902   -5.482  1.000 52.583  0 76  ILE   B CG2   1 ? 
ATOM   1880 C  CD1   . ILE   B 1 76  ? 3.733   11.775  -6.792  1.000 61.665  0 76  ILE   B CD1   1 ? 
ATOM   1881 N  N     . LYS   B 1 77  ? 0.159   8.647   -4.008  1.000 47.954  0 77  LYS   B N     1 ? 
ATOM   1882 C  CA    . LYS   B 1 77  ? -0.008  7.840   -2.808  1.000 47.410  0 77  LYS   B CA    1 ? 
ATOM   1883 C  C     . LYS   B 1 77  ? -1.103  6.790   -2.969  1.000 46.493  0 77  LYS   B C     1 ? 
ATOM   1884 O  O     . LYS   B 1 77  ? -0.963  5.727   -2.386  1.000 46.231  0 77  LYS   B O     1 ? 
ATOM   1885 C  CB    . LYS   B 1 77  ? -0.232  8.650   -1.528  1.000 48.785  0 77  LYS   B CB    1 ? 
ATOM   1886 C  CG    . LYS   B 1 77  ? -1.618  9.105   -1.245  1.000 52.290  0 77  LYS   B CG    1 ? 
ATOM   1887 C  CD    . LYS   B 1 77  ? -1.707  9.927   0.026   1.000 54.060  0 77  LYS   B CD    1 ? 
ATOM   1888 C  CE    . LYS   B 1 77  ? -3.161  10.149  0.265   1.000 54.194  0 77  LYS   B CE    1 ? 
ATOM   1889 N  NZ    . LYS   B 1 77  ? -3.415  11.256  1.190   1.000 60.227  0 77  LYS   B NZ    1 ? 
ATOM   1890 N  N     . THR   B 1 78  ? -2.151  7.020   -3.777  1.000 51.702  0 78  THR   B N     1 ? 
ATOM   1891 C  CA    . THR   B 1 78  ? -3.231  6.038   -3.859  1.000 55.252  0 78  THR   B CA    1 ? 
ATOM   1892 C  C     . THR   B 1 78  ? -3.037  5.034   -5.005  1.000 56.133  0 78  THR   B C     1 ? 
ATOM   1893 O  O     . THR   B 1 78  ? -3.903  4.211   -5.197  1.000 51.220  0 78  THR   B O     1 ? 
ATOM   1894 C  CB    . THR   B 1 78  ? -4.566  6.761   -3.987  1.000 56.224  0 78  THR   B CB    1 ? 
ATOM   1895 O  OG1   . THR   B 1 78  ? -4.503  7.518   -5.190  1.000 52.049  0 78  THR   B OG1   1 ? 
ATOM   1896 C  CG2   . THR   B 1 78  ? -4.822  7.640   -2.785  1.000 56.941  0 78  THR   B CG2   1 ? 
ATOM   1897 N  N     . ASN   B 1 79  ? -1.921  5.066   -5.743  1.000 56.669  0 79  ASN   B N     1 ? 
ATOM   1898 C  CA    . ASN   B 1 79  ? -1.684  4.112   -6.822  1.000 57.667  0 79  ASN   B CA    1 ? 
ATOM   1899 C  C     . ASN   B 1 79  ? -0.464  3.229   -6.537  1.000 62.800  0 79  ASN   B C     1 ? 
ATOM   1900 O  O     . ASN   B 1 79  ? 0.355   3.519   -5.663  1.000 56.674  0 79  ASN   B O     1 ? 
ATOM   1901 C  CB    . ASN   B 1 79  ? -1.619  4.853   -8.153  1.000 57.981  0 79  ASN   B CB    1 ? 
ATOM   1902 C  CG    . ASN   B 1 79  ? -3.007  5.307   -8.548  1.000 58.601  0 79  ASN   B CG    1 ? 
ATOM   1903 O  OD1   . ASN   B 1 79  ? -3.924  4.480   -8.696  1.000 53.325  0 79  ASN   B OD1   1 ? 
ATOM   1904 N  ND2   . ASN   B 1 79  ? -3.187  6.611   -8.691  1.000 53.757  0 79  ASN   B ND2   1 ? 
ATOM   1905 N  N     . ASP   B 1 80  ? -0.348  2.119   -7.274  1.000 55.557  0 80  ASP   B N     1 ? 
ATOM   1906 C  CA    . ASP   B 1 80  ? 0.582   1.075   -6.875  1.000 50.943  0 80  ASP   B CA    1 ? 
ATOM   1907 C  C     . ASP   B 1 80  ? 2.007   1.488   -7.200  1.000 49.343  0 80  ASP   B C     1 ? 
ATOM   1908 O  O     . ASP   B 1 80  ? 2.937   1.174   -6.478  1.000 56.290  0 80  ASP   B O     1 ? 
ATOM   1909 C  CB    . ASP   B 1 80  ? 0.230   -0.257  -7.511  1.000 58.361  0 80  ASP   B CB    1 ? 
ATOM   1910 C  CG    . ASP   B 1 80  ? -1.156  -0.756  -7.122  1.000 65.009  0 80  ASP   B CG    1 ? 
ATOM   1911 O  OD1   . ASP   B 1 80  ? -1.349  -1.027  -5.930  1.000 68.718  0 80  ASP   B OD1   1 ? 
ATOM   1912 O  OD2   . ASP   B 1 80  ? -2.036  -0.820  -8.003  1.000 67.855  0 80  ASP   B OD2   1 ? 
ATOM   1913 N  N     . ILE   B 1 81  ? 2.188   2.193   -8.307  1.000 51.867  0 81  ILE   B N     1 ? 
ATOM   1914 C  CA    . ILE   B 1 81  ? 3.514   2.316   -8.863  1.000 52.931  0 81  ILE   B CA    1 ? 
ATOM   1915 C  C     . ILE   B 1 81  ? 3.748   3.738   -9.348  1.000 55.269  0 81  ILE   B C     1 ? 
ATOM   1916 O  O     . ILE   B 1 81  ? 2.833   4.407   -9.825  1.000 55.404  0 81  ILE   B O     1 ? 
ATOM   1917 C  CB    . ILE   B 1 81  ? 3.702   1.223   -9.934  1.000 61.287  0 81  ILE   B CB    1 ? 
ATOM   1918 C  CG1   . ILE   B 1 81  ? 3.874   -0.116  -9.220  1.000 65.165  0 81  ILE   B CG1   1 ? 
ATOM   1919 C  CG2   . ILE   B 1 81  ? 4.854   1.532   -10.876 1.000 54.253  0 81  ILE   B CG2   1 ? 
ATOM   1920 C  CD1   . ILE   B 1 81  ? 4.052   -1.307  -10.119 1.000 72.466  0 81  ILE   B CD1   1 ? 
ATOM   1921 N  N     . MET   B 1 82  ? 4.994   4.200   -9.158  1.000 53.817  0 82  MET   B N     1 ? 
ATOM   1922 C  CA    . MET   B 1 82  ? 5.420   5.511   -9.626  1.000 49.431  0 82  MET   B CA    1 ? 
ATOM   1923 C  C     . MET   B 1 82  ? 6.229   5.363   -10.914 1.000 51.035  0 82  MET   B C     1 ? 
ATOM   1924 O  O     . MET   B 1 82  ? 7.294   4.738   -10.897 1.000 49.075  0 82  MET   B O     1 ? 
ATOM   1925 C  CB    . MET   B 1 82  ? 6.346   6.176   -8.605  1.000 48.047  0 82  MET   B CB    1 ? 
ATOM   1926 C  CG    . MET   B 1 82  ? 6.936   7.494   -9.068  1.000 51.702  0 82  MET   B CG    1 ? 
ATOM   1927 S  SD    . MET   B 1 82  ? 5.655   8.747   -9.228  1.000 53.588  0 82  MET   B SD    1 ? 
ATOM   1928 C  CE    . MET   B 1 82  ? 6.574   9.962   -10.169 1.000 48.709  0 82  MET   B CE    1 ? 
ATOM   1929 N  N     . LEU   B 1 83  ? 5.733   6.021   -11.970 1.000 51.785  0 83  LEU   B N     1 ? 
ATOM   1930 C  CA    . LEU   B 1 83  ? 6.337   6.008   -13.287 1.000 52.588  0 83  LEU   B CA    1 ? 
ATOM   1931 C  C     . LEU   B 1 83  ? 6.873   7.398   -13.575 1.000 49.688  0 83  LEU   B C     1 ? 
ATOM   1932 O  O     . LEU   B 1 83  ? 6.134   8.371   -13.520 1.000 55.888  0 83  LEU   B O     1 ? 
ATOM   1933 C  CB    . LEU   B 1 83  ? 5.323   5.628   -14.363 1.000 57.317  0 83  LEU   B CB    1 ? 
ATOM   1934 C  CG    . LEU   B 1 83  ? 5.924   5.385   -15.752 1.000 65.953  0 83  LEU   B CG    1 ? 
ATOM   1935 C  CD1   . LEU   B 1 83  ? 6.701   4.085   -15.734 1.000 66.602  0 83  LEU   B CD1   1 ? 
ATOM   1936 C  CD2   . LEU   B 1 83  ? 4.902   5.358   -16.853 1.000 67.627  0 83  LEU   B CD2   1 ? 
ATOM   1937 N  N     . GLY   B 1 84  ? 8.152   7.458   -13.923 1.000 45.080  0 84  GLY   B N     1 ? 
ATOM   1938 C  CA    . GLY   B 1 84  ? 8.775   8.702   -14.298 1.000 51.640  0 84  GLY   B CA    1 ? 
ATOM   1939 C  C     . GLY   B 1 84  ? 9.288   8.635   -15.730 1.000 53.164  0 84  GLY   B C     1 ? 
ATOM   1940 O  O     . GLY   B 1 84  ? 10.328  8.048   -15.992 1.000 57.790  0 84  GLY   B O     1 ? 
ATOM   1941 N  N     . VAL   B 1 85  ? 8.575   9.292   -16.641 1.000 56.062  0 85  VAL   B N     1 ? 
ATOM   1942 C  CA    . VAL   B 1 85  ? 9.071   9.483   -17.994 1.000 55.135  0 85  VAL   B CA    1 ? 
ATOM   1943 C  C     . VAL   B 1 85  ? 10.165  10.536  -17.913 1.000 50.001  0 85  VAL   B C     1 ? 
ATOM   1944 O  O     . VAL   B 1 85  ? 9.905   11.668  -17.526 1.000 57.431  0 85  VAL   B O     1 ? 
ATOM   1945 C  CB    . VAL   B 1 85  ? 7.896   9.881   -18.913 1.000 55.766  0 85  VAL   B CB    1 ? 
ATOM   1946 C  CG1   . VAL   B 1 85  ? 8.314   10.169  -20.352 1.000 58.790  0 85  VAL   B CG1   1 ? 
ATOM   1947 C  CG2   . VAL   B 1 85  ? 6.816   8.800   -18.901 1.000 53.514  0 85  VAL   B CG2   1 ? 
ATOM   1948 N  N     . TYR   B 1 86  ? 11.389  10.158  -18.281 1.000 53.005  0 86  TYR   B N     1 ? 
ATOM   1949 C  CA    . TYR   B 1 86  ? 12.581  10.894  -17.924 1.000 48.399  0 86  TYR   B CA    1 ? 
ATOM   1950 C  C     . TYR   B 1 86  ? 13.433  11.206  -19.158 1.000 51.578  0 86  TYR   B C     1 ? 
ATOM   1951 O  O     . TYR   B 1 86  ? 13.917  10.282  -19.819 1.000 49.851  0 86  TYR   B O     1 ? 
ATOM   1952 C  CB    . TYR   B 1 86  ? 13.332  10.001  -16.928 1.000 52.629  0 86  TYR   B CB    1 ? 
ATOM   1953 C  CG    . TYR   B 1 86  ? 14.376  10.764  -16.115 1.000 57.758  0 86  TYR   B CG    1 ? 
ATOM   1954 C  CD1   . TYR   B 1 86  ? 15.627  11.078  -16.635 1.000 56.064  0 86  TYR   B CD1   1 ? 
ATOM   1955 C  CD2   . TYR   B 1 86  ? 14.085  11.211  -14.828 1.000 57.843  0 86  TYR   B CD2   1 ? 
ATOM   1956 C  CE1   . TYR   B 1 86  ? 16.553  11.813  -15.904 1.000 54.373  0 86  TYR   B CE1   1 ? 
ATOM   1957 C  CE2   . TYR   B 1 86  ? 14.999  11.934  -14.088 1.000 49.031  0 86  TYR   B CE2   1 ? 
ATOM   1958 C  CZ    . TYR   B 1 86  ? 16.243  12.235  -14.621 1.000 51.723  0 86  TYR   B CZ    1 ? 
ATOM   1959 O  OH    . TYR   B 1 86  ? 17.141  12.944  -13.874 1.000 50.356  0 86  TYR   B OH    1 ? 
ATOM   1960 N  N     . ILE   B 1 87  ? 13.654  12.506  -19.412 1.000 52.472  0 87  ILE   B N     1 ? 
ATOM   1961 C  CA    . ILE   B 1 87  ? 14.479  12.973  -20.513 1.000 54.175  0 87  ILE   B CA    1 ? 
ATOM   1962 C  C     . ILE   B 1 87  ? 15.802  13.481  -19.956 1.000 54.096  0 87  ILE   B C     1 ? 
ATOM   1963 O  O     . ILE   B 1 87  ? 15.824  14.531  -19.315 1.000 58.489  0 87  ILE   B O     1 ? 
ATOM   1964 C  CB    . ILE   B 1 87  ? 13.785  14.078  -21.329 1.000 62.911  0 87  ILE   B CB    1 ? 
ATOM   1965 C  CG1   . ILE   B 1 87  ? 12.526  13.584  -22.053 1.000 78.794  0 87  ILE   B CG1   1 ? 
ATOM   1966 C  CG2   . ILE   B 1 87  ? 14.771  14.665  -22.335 1.000 63.611  0 87  ILE   B CG2   1 ? 
ATOM   1967 C  CD1   . ILE   B 1 87  ? 11.412  13.130  -21.141 1.000 79.203  0 87  ILE   B CD1   1 ? 
ATOM   1968 N  N     . PRO   B 1 88  ? 16.930  12.773  -20.189 1.000 52.628  0 88  PRO   B N     1 ? 
ATOM   1969 C  CA    . PRO   B 1 88  ? 18.221  13.143  -19.602 1.000 54.610  0 88  PRO   B CA    1 ? 
ATOM   1970 C  C     . PRO   B 1 88  ? 18.711  14.551  -19.900 1.000 61.966  0 88  PRO   B C     1 ? 
ATOM   1971 O  O     . PRO   B 1 88  ? 19.383  15.169  -19.074 1.000 77.424  0 88  PRO   B O     1 ? 
ATOM   1972 C  CB    . PRO   B 1 88  ? 19.182  12.068  -20.135 1.000 54.028  0 88  PRO   B CB    1 ? 
ATOM   1973 C  CG    . PRO   B 1 88  ? 18.262  10.871  -20.363 1.000 52.150  0 88  PRO   B CG    1 ? 
ATOM   1974 C  CD    . PRO   B 1 88  ? 16.999  11.520  -20.955 1.000 57.147  0 88  PRO   B CD    1 ? 
ATOM   1975 N  N     . ASP   B 1 89  ? 18.351  15.062  -21.078 1.000 65.266  0 89  ASP   B N     1 ? 
ATOM   1976 C  CA    . ASP   B 1 89  ? 18.728  16.416  -21.465 1.000 69.151  0 89  ASP   B CA    1 ? 
ATOM   1977 C  C     . ASP   B 1 89  ? 17.738  17.457  -20.947 1.000 62.339  0 89  ASP   B C     1 ? 
ATOM   1978 O  O     . ASP   B 1 89  ? 17.991  18.637  -21.072 1.000 63.476  0 89  ASP   B O     1 ? 
ATOM   1979 C  CB    . ASP   B 1 89  ? 18.782  16.576  -22.979 1.000 74.587  0 89  ASP   B CB    1 ? 
ATOM   1980 C  CG    . ASP   B 1 89  ? 19.688  15.585  -23.697 1.000 77.878  0 89  ASP   B CG    1 ? 
ATOM   1981 O  OD1   . ASP   B 1 89  ? 20.927  15.699  -23.541 1.000 67.650  0 89  ASP   B OD1   1 ? 
ATOM   1982 O  OD2   . ASP   B 1 89  ? 19.132  14.673  -24.359 1.000 82.133  0 89  ASP   B OD2   1 ? 
ATOM   1983 N  N     . GLU   B 1 90  ? 16.575  17.036  -20.440 1.000 63.282  0 90  GLU   B N     1 ? 
ATOM   1984 C  CA    . GLU   B 1 90  ? 15.538  17.957  -20.004 1.000 67.956  0 90  GLU   B CA    1 ? 
ATOM   1985 C  C     . GLU   B 1 90  ? 15.031  17.516  -18.627 1.000 62.519  0 90  GLU   B C     1 ? 
ATOM   1986 O  O     . GLU   B 1 90  ? 13.863  17.168  -18.449 1.000 55.638  0 90  GLU   B O     1 ? 
ATOM   1987 C  CB    . GLU   B 1 90  ? 14.450  18.020  -21.081 1.000 73.965  0 90  GLU   B CB    1 ? 
ATOM   1988 C  CG    . GLU   B 1 90  ? 14.936  18.561  -22.433 1.000 75.903  0 90  GLU   B CG    1 ? 
ATOM   1989 C  CD    . GLU   B 1 90  ? 13.861  18.782  -23.496 1.000 76.328  0 90  GLU   B CD    1 ? 
ATOM   1990 O  OE1   . GLU   B 1 90  ? 14.230  19.407  -24.508 1.000 81.486  0 90  GLU   B OE1   1 ? 
ATOM   1991 O  OE2   . GLU   B 1 90  ? 12.689  18.338  -23.350 1.000 63.113  0 90  GLU   B OE2   1 ? 
ATOM   1992 N  N     . GLU   B 1 91  ? 15.934  17.480  -17.648 1.000 56.320  0 91  GLU   B N     1 ? 
ATOM   1993 C  CA    . GLU   B 1 91  ? 15.580  16.881  -16.369 1.000 60.810  0 91  GLU   B CA    1 ? 
ATOM   1994 C  C     . GLU   B 1 91  ? 14.637  17.836  -15.642 1.000 57.222  0 91  GLU   B C     1 ? 
ATOM   1995 O  O     . GLU   B 1 91  ? 14.758  19.041  -15.807 1.000 55.948  0 91  GLU   B O     1 ? 
ATOM   1996 C  CB    . GLU   B 1 91  ? 16.852  16.545  -15.607 1.000 62.287  0 91  GLU   B CB    1 ? 
ATOM   1997 C  CG    . GLU   B 1 91  ? 17.630  15.372  -16.206 1.000 63.976  0 91  GLU   B CG    1 ? 
ATOM   1998 C  CD    . GLU   B 1 91  ? 18.915  15.067  -15.438 1.000 55.338  0 91  GLU   B CD    1 ? 
ATOM   1999 O  OE1   . GLU   B 1 91  ? 19.769  15.958  -15.466 1.000 53.830  0 91  GLU   B OE1   1 ? 
ATOM   2000 O  OE2   . GLU   B 1 91  ? 19.085  13.984  -14.825 1.000 51.767  0 91  GLU   B OE2   1 ? 
ATOM   2001 N  N     . ASP   B 1 92  ? 13.660  17.287  -14.921 1.000 54.640  0 92  ASP   B N     1 ? 
ATOM   2002 C  CA    . ASP   B 1 92  ? 12.561  18.077  -14.397 1.000 54.588  0 92  ASP   B CA    1 ? 
ATOM   2003 C  C     . ASP   B 1 92  ? 12.542  18.060  -12.865 1.000 55.562  0 92  ASP   B C     1 ? 
ATOM   2004 O  O     . ASP   B 1 92  ? 12.441  17.000  -12.241 1.000 52.597  0 92  ASP   B O     1 ? 
ATOM   2005 C  CB    . ASP   B 1 92  ? 11.221  17.628  -14.962 1.000 55.146  0 92  ASP   B CB    1 ? 
ATOM   2006 C  CG    . ASP   B 1 92  ? 10.069  18.535  -14.547 1.000 61.162  0 92  ASP   B CG    1 ? 
ATOM   2007 O  OD1   . ASP   B 1 92  ? 10.010  19.705  -15.030 1.000 78.134  0 92  ASP   B OD1   1 ? 
ATOM   2008 O  OD2   . ASP   B 1 92  ? 9.280   18.106  -13.694 1.000 63.240  0 92  ASP   B OD2   1 ? 
ATOM   2009 N  N     . VAL   B 1 93  ? 12.593  19.260  -12.276 1.000 45.121  0 93  VAL   B N     1 ? 
ATOM   2010 C  CA    . VAL   B 1 93  ? 12.600  19.422  -10.834 1.000 49.179  0 93  VAL   B CA    1 ? 
ATOM   2011 C  C     . VAL   B 1 93  ? 11.306  18.873  -10.229 1.000 47.586  0 93  VAL   B C     1 ? 
ATOM   2012 O  O     . VAL   B 1 93  ? 11.346  18.286  -9.155  1.000 57.220  0 93  VAL   B O     1 ? 
ATOM   2013 C  CB    . VAL   B 1 93  ? 12.822  20.878  -10.387 1.000 45.903  0 93  VAL   B CB    1 ? 
ATOM   2014 C  CG1   . VAL   B 1 93  ? 11.682  21.781  -10.824 1.000 47.983  0 93  VAL   B CG1   1 ? 
ATOM   2015 C  CG2   . VAL   B 1 93  ? 13.036  20.980  -8.881  1.000 44.494  0 93  VAL   B CG2   1 ? 
ATOM   2016 N  N     . GLY   B 1 94  ? 10.167  19.096  -10.883 1.000 47.731  0 94  GLY   B N     1 ? 
ATOM   2017 C  CA    . GLY   B 1 94  ? 8.883   18.645  -10.366 1.000 49.680  0 94  GLY   B CA    1 ? 
ATOM   2018 C  C     . GLY   B 1 94  ? 8.845   17.121  -10.258 1.000 54.841  0 94  GLY   B C     1 ? 
ATOM   2019 O  O     . GLY   B 1 94  ? 8.445   16.569  -9.233  1.000 50.070  0 94  GLY   B O     1 ? 
ATOM   2020 N  N     . LEU   B 1 95  ? 9.293   16.448  -11.323 1.000 48.333  0 95  LEU   B N     1 ? 
ATOM   2021 C  CA    . LEU   B 1 95  ? 9.364   14.999  -11.323 1.000 52.754  0 95  LEU   B CA    1 ? 
ATOM   2022 C  C     . LEU   B 1 95  ? 10.292  14.552  -10.204 1.000 48.860  0 95  LEU   B C     1 ? 
ATOM   2023 O  O     . LEU   B 1 95  ? 10.014  13.573  -9.528  1.000 45.139  0 95  LEU   B O     1 ? 
ATOM   2024 C  CB    . LEU   B 1 95  ? 9.866   14.476  -12.665 1.000 51.587  0 95  LEU   B CB    1 ? 
ATOM   2025 C  CG    . LEU   B 1 95  ? 9.965   12.952  -12.784 1.000 54.540  0 95  LEU   B CG    1 ? 
ATOM   2026 C  CD1   . LEU   B 1 95  ? 8.645   12.304  -12.418 1.000 46.814  0 95  LEU   B CD1   1 ? 
ATOM   2027 C  CD2   . LEU   B 1 95  ? 10.350  12.508  -14.196 1.000 57.438  0 95  LEU   B CD2   1 ? 
ATOM   2028 N  N     . GLY   B 1 96  ? 11.433  15.240  -10.068 1.000 42.921  0 96  GLY   B N     1 ? 
ATOM   2029 C  CA    . GLY   B 1 96  ? 12.383  14.870  -9.040  1.000 52.039  0 96  GLY   B CA    1 ? 
ATOM   2030 C  C     . GLY   B 1 96  ? 11.697  14.825  -7.669  1.000 51.763  0 96  GLY   B C     1 ? 
ATOM   2031 O  O     . GLY   B 1 96  ? 11.813  13.846  -6.950  1.000 47.905  0 96  GLY   B O     1 ? 
ATOM   2032 N  N     . MET   B 1 97  ? 10.948  15.879  -7.349  1.000 46.581  0 97  MET   B N     1 ? 
ATOM   2033 C  CA    . MET   B 1 97  ? 10.226  15.979  -6.097  1.000 48.070  0 97  MET   B CA    1 ? 
ATOM   2034 C  C     . MET   B 1 97  ? 9.279   14.790  -5.938  1.000 51.157  0 97  MET   B C     1 ? 
ATOM   2035 O  O     . MET   B 1 97  ? 9.261   14.125  -4.886  1.000 46.111  0 97  MET   B O     1 ? 
ATOM   2036 C  CB    . MET   B 1 97  ? 9.482   17.318  -6.063  1.000 47.434  0 97  MET   B CB    1 ? 
ATOM   2037 C  CG    . MET   B 1 97  ? 8.692   17.552  -4.797  1.000 50.562  0 97  MET   B CG    1 ? 
ATOM   2038 S  SD    . MET   B 1 97  ? 7.095   16.749  -4.934  1.000 53.395  0 97  MET   B SD    1 ? 
ATOM   2039 C  CE    . MET   B 1 97  ? 6.610   16.578  -3.211  1.000 51.090  0 97  MET   B CE    1 ? 
ATOM   2040 N  N     . GLU   B 1 98  ? 8.512   14.512  -6.996  1.000 52.297  0 98  GLU   B N     1 ? 
ATOM   2041 C  CA    . GLU   B 1 98  ? 7.518   13.438  -6.974  1.000 49.911  0 98  GLU   B CA    1 ? 
ATOM   2042 C  C     . GLU   B 1 98  ? 8.186   12.078  -6.749  1.000 45.502  0 98  GLU   B C     1 ? 
ATOM   2043 O  O     . GLU   B 1 98  ? 7.617   11.195  -6.115  1.000 48.974  0 98  GLU   B O     1 ? 
ATOM   2044 C  CB    . GLU   B 1 98  ? 6.773   13.395  -8.308  1.000 48.861  0 98  GLU   B CB    1 ? 
ATOM   2045 C  CG    . GLU   B 1 98  ? 5.823   14.568  -8.521  1.000 59.426  0 98  GLU   B CG    1 ? 
ATOM   2046 C  CD    . GLU   B 1 98  ? 5.342   14.775  -9.960  1.000 57.677  0 98  GLU   B CD    1 ? 
ATOM   2047 O  OE1   . GLU   B 1 98  ? 4.407   15.594  -10.138 1.000 62.822  0 98  GLU   B OE1   1 ? 
ATOM   2048 O  OE2   . GLU   B 1 98  ? 5.934   14.198  -10.914 1.000 54.327  0 98  GLU   B OE2   1 ? 
ATOM   2049 N  N     . LEU   B 1 99  ? 9.370   11.882  -7.336  1.000 49.749  0 99  LEU   B N     1 ? 
ATOM   2050 C  CA    . LEU   B 1 99  ? 10.132  10.659  -7.129  1.000 46.746  0 99  LEU   B CA    1 ? 
ATOM   2051 C  C     . LEU   B 1 99  ? 10.462  10.492  -5.643  1.000 50.825  0 99  LEU   B C     1 ? 
ATOM   2052 O  O     . LEU   B 1 99  ? 10.297  9.413   -5.074  1.000 47.630  0 99  LEU   B O     1 ? 
ATOM   2053 C  CB    . LEU   B 1 99  ? 11.402  10.708  -7.970  1.000 45.868  0 99  LEU   B CB    1 ? 
ATOM   2054 C  CG    . LEU   B 1 99  ? 11.223  10.686  -9.495  1.000 52.686  0 99  LEU   B CG    1 ? 
ATOM   2055 C  CD1   . LEU   B 1 99  ? 12.583  10.805  -10.163 1.000 51.845  0 99  LEU   B CD1   1 ? 
ATOM   2056 C  CD2   . LEU   B 1 99  ? 10.519  9.424   -10.007 1.000 56.916  0 99  LEU   B CD2   1 ? 
ATOM   2057 N  N     . GLY   B 1 100 ? 10.914  11.580  -5.012  1.000 45.604  0 100 GLY   B N     1 ? 
ATOM   2058 C  CA    . GLY   B 1 100 ? 11.198  11.571  -3.586  1.000 47.581  0 100 GLY   B CA    1 ? 
ATOM   2059 C  C     . GLY   B 1 100 ? 9.959   11.266  -2.745  1.000 47.867  0 100 GLY   B C     1 ? 
ATOM   2060 O  O     . GLY   B 1 100 ? 10.024  10.485  -1.814  1.000 50.401  0 100 GLY   B O     1 ? 
ATOM   2061 N  N     . TYR   B 1 101 ? 8.811   11.823  -3.126  1.000 48.338  0 101 TYR   B N     1 ? 
ATOM   2062 C  CA    . TYR   B 1 101 ? 7.582   11.532  -2.419  1.000 45.141  0 101 TYR   B CA    1 ? 
ATOM   2063 C  C     . TYR   B 1 101 ? 7.210   10.056  -2.610  1.000 47.624  0 101 TYR   B C     1 ? 
ATOM   2064 O  O     . TYR   B 1 101 ? 6.865   9.387   -1.646  1.000 46.742  0 101 TYR   B O     1 ? 
ATOM   2065 C  CB    . TYR   B 1 101 ? 6.544   12.582  -2.842  1.000 45.433  0 101 TYR   B CB    1 ? 
ATOM   2066 C  CG    . TYR   B 1 101 ? 5.202   12.406  -2.156  1.000 48.126  0 101 TYR   B CG    1 ? 
ATOM   2067 C  CD1   . TYR   B 1 101 ? 4.995   12.833  -0.848  1.000 52.212  0 101 TYR   B CD1   1 ? 
ATOM   2068 C  CD2   . TYR   B 1 101 ? 4.177   11.722  -2.790  1.000 50.164  0 101 TYR   B CD2   1 ? 
ATOM   2069 C  CE1   . TYR   B 1 101 ? 3.783   12.622  -0.206  1.000 51.635  0 101 TYR   B CE1   1 ? 
ATOM   2070 C  CE2   . TYR   B 1 101 ? 2.954   11.539  -2.176  1.000 55.247  0 101 TYR   B CE2   1 ? 
ATOM   2071 C  CZ    . TYR   B 1 101 ? 2.755   11.987  -0.883  1.000 56.468  0 101 TYR   B CZ    1 ? 
ATOM   2072 O  OH    . TYR   B 1 101 ? 1.532   11.759  -0.334  1.000 59.396  0 101 TYR   B OH    1 ? 
ATOM   2073 N  N     . ALA   B 1 102 ? 7.310   9.538   -3.837  1.000 48.193  0 102 ALA   B N     1 ? 
ATOM   2074 C  CA    . ALA   B 1 102 ? 6.976   8.150   -4.127  1.000 52.015  0 102 ALA   B CA    1 ? 
ATOM   2075 C  C     . ALA   B 1 102 ? 7.813   7.194   -3.272  1.000 42.434  0 102 ALA   B C     1 ? 
ATOM   2076 O  O     . ALA   B 1 102 ? 7.282   6.246   -2.705  1.000 47.631  0 102 ALA   B O     1 ? 
ATOM   2077 C  CB    . ALA   B 1 102 ? 7.188   7.865   -5.598  1.000 54.733  0 102 ALA   B CB    1 ? 
ATOM   2078 N  N     . LEU   B 1 103 ? 9.120   7.457   -3.179  1.000 50.665  0 103 LEU   B N     1 ? 
ATOM   2079 C  CA    . LEU   B 1 103 ? 10.008  6.703   -2.312  1.000 49.541  0 103 LEU   B CA    1 ? 
ATOM   2080 C  C     . LEU   B 1 103 ? 9.458   6.712   -0.892  1.000 51.231  0 103 LEU   B C     1 ? 
ATOM   2081 O  O     . LEU   B 1 103 ? 9.307   5.673   -0.261  1.000 49.461  0 103 LEU   B O     1 ? 
ATOM   2082 C  CB    . LEU   B 1 103 ? 11.410  7.302   -2.312  1.000 54.873  0 103 LEU   B CB    1 ? 
ATOM   2083 C  CG    . LEU   B 1 103 ? 12.377  6.729   -1.268  1.000 65.125  0 103 LEU   B CG    1 ? 
ATOM   2084 C  CD1   . LEU   B 1 103 ? 12.744  5.255   -1.562  1.000 56.908  0 103 LEU   B CD1   1 ? 
ATOM   2085 C  CD2   . LEU   B 1 103 ? 13.616  7.623   -1.165  1.000 65.282  0 103 LEU   B CD2   1 ? 
ATOM   2086 N  N     . SER   B 1 104 ? 9.110   7.899   -0.410  1.000 55.622  0 104 SER   B N     1 ? 
ATOM   2087 C  CA    . SER   B 1 104 ? 8.621   8.028   0.947   1.000 56.281  0 104 SER   B CA    1 ? 
ATOM   2088 C  C     . SER   B 1 104 ? 7.307   7.267   1.137   1.000 61.140  0 104 SER   B C     1 ? 
ATOM   2089 O  O     . SER   B 1 104 ? 6.933   6.924   2.267   1.000 52.543  0 104 SER   B O     1 ? 
ATOM   2090 C  CB    . SER   B 1 104 ? 8.448   9.478   1.307   1.000 54.913  0 104 SER   B CB    1 ? 
ATOM   2091 O  OG    . SER   B 1 104 ? 7.181   9.996   0.910   1.000 56.415  0 104 SER   B OG    1 ? 
ATOM   2092 N  N     . GLN   B 1 105 ? 6.547   7.064   0.050   1.000 51.631  0 105 GLN   B N     1 ? 
ATOM   2093 C  CA    . GLN   B 1 105 ? 5.265   6.389   0.210   1.000 53.388  0 105 GLN   B CA    1 ? 
ATOM   2094 C  C     . GLN   B 1 105 ? 5.403   4.892   -0.038  1.000 49.872  0 105 GLN   B C     1 ? 
ATOM   2095 O  O     . GLN   B 1 105 ? 4.416   4.187   -0.036  1.000 52.131  0 105 GLN   B O     1 ? 
ATOM   2096 C  CB    . GLN   B 1 105 ? 4.203   6.976   -0.706  1.000 54.628  0 105 GLN   B CB    1 ? 
ATOM   2097 C  CG    . GLN   B 1 105 ? 3.838   8.405   -0.347  1.000 49.231  0 105 GLN   B CG    1 ? 
ATOM   2098 C  CD    . GLN   B 1 105 ? 3.126   8.504   0.978   1.000 53.824  0 105 GLN   B CD    1 ? 
ATOM   2099 O  OE1   . GLN   B 1 105 ? 2.236   7.718   1.312   1.000 53.907  0 105 GLN   B OE1   1 ? 
ATOM   2100 N  NE2   . GLN   B 1 105 ? 3.511   9.489   1.759   1.000 55.993  0 105 GLN   B NE2   1 ? 
ATOM   2101 N  N     . GLY   B 1 106 ? 6.629   4.391   -0.210  1.000 51.869  0 106 GLY   B N     1 ? 
ATOM   2102 C  CA    . GLY   B 1 106 ? 6.832   2.956   -0.329  1.000 57.490  0 106 GLY   B CA    1 ? 
ATOM   2103 C  C     . GLY   B 1 106 ? 6.494   2.403   -1.720  1.000 62.394  0 106 GLY   B C     1 ? 
ATOM   2104 O  O     . GLY   B 1 106 ? 6.215   1.224   -1.834  1.000 56.996  0 106 GLY   B O     1 ? 
ATOM   2105 N  N     . LYS   B 1 107 ? 6.532   3.236   -2.772  1.000 50.664  0 107 LYS   B N     1 ? 
ATOM   2106 C  CA    . LYS   B 1 107 ? 6.166   2.796   -4.104  1.000 58.323  0 107 LYS   B CA    1 ? 
ATOM   2107 C  C     . LYS   B 1 107 ? 7.399   2.311   -4.861  1.000 54.412  0 107 LYS   B C     1 ? 
ATOM   2108 O  O     . LYS   B 1 107 ? 8.478   2.874   -4.713  1.000 50.467  0 107 LYS   B O     1 ? 
ATOM   2109 C  CB    . LYS   B 1 107 ? 5.596   3.963   -4.920  1.000 57.809  0 107 LYS   B CB    1 ? 
ATOM   2110 C  CG    . LYS   B 1 107 ? 4.398   4.663   -4.286  1.000 61.211  0 107 LYS   B CG    1 ? 
ATOM   2111 C  CD    . LYS   B 1 107 ? 3.241   3.742   -3.899  1.000 56.773  0 107 LYS   B CD    1 ? 
ATOM   2112 C  CE    . LYS   B 1 107 ? 2.229   4.529   -3.171  1.000 59.917  0 107 LYS   B CE    1 ? 
ATOM   2113 N  NZ    . LYS   B 1 107 ? 0.997   3.771   -2.945  1.000 56.611  0 107 LYS   B NZ    1 ? 
ATOM   2114 N  N     . TYR   B 1 108 ? 7.206   1.315   -5.728  1.000 53.401  0 108 TYR   B N     1 ? 
ATOM   2115 C  CA    . TYR   B 1 108 ? 8.174   1.017   -6.770  1.000 52.336  0 108 TYR   B CA    1 ? 
ATOM   2116 C  C     . TYR   B 1 108 ? 8.329   2.244   -7.663  1.000 50.948  0 108 TYR   B C     1 ? 
ATOM   2117 O  O     . TYR   B 1 108 ? 7.346   2.849   -8.089  1.000 55.009  0 108 TYR   B O     1 ? 
ATOM   2118 C  CB    . TYR   B 1 108 ? 7.740   -0.173  -7.618  1.000 53.060  0 108 TYR   B CB    1 ? 
ATOM   2119 C  CG    . TYR   B 1 108 ? 8.790   -0.678  -8.590  1.000 48.442  0 108 TYR   B CG    1 ? 
ATOM   2120 C  CD1   . TYR   B 1 108 ? 9.931   -1.323  -8.122  1.000 55.503  0 108 TYR   B CD1   1 ? 
ATOM   2121 C  CD2   . TYR   B 1 108 ? 8.590   -0.624  -9.966  1.000 47.094  0 108 TYR   B CD2   1 ? 
ATOM   2122 C  CE1   . TYR   B 1 108 ? 10.907  -1.807  -8.983  1.000 53.245  0 108 TYR   B CE1   1 ? 
ATOM   2123 C  CE2   . TYR   B 1 108 ? 9.530   -1.156  -10.840 1.000 48.241  0 108 TYR   B CE2   1 ? 
ATOM   2124 C  CZ    . TYR   B 1 108 ? 10.700  -1.716  -10.348 1.000 48.842  0 108 TYR   B CZ    1 ? 
ATOM   2125 O  OH    . TYR   B 1 108 ? 11.659  -2.232  -11.158 1.000 51.397  0 108 TYR   B OH    1 ? 
ATOM   2126 N  N     . VAL   B 1 109 ? 9.587   2.627   -7.893  1.000 49.090  0 109 VAL   B N     1 ? 
ATOM   2127 C  CA    . VAL   B 1 109 ? 9.893   3.814   -8.668  1.000 55.341  0 109 VAL   B CA    1 ? 
ATOM   2128 C  C     . VAL   B 1 109 ? 10.609  3.396   -9.949  1.000 49.109  0 109 VAL   B C     1 ? 
ATOM   2129 O  O     . VAL   B 1 109 ? 11.787  3.042   -9.914  1.000 50.817  0 109 VAL   B O     1 ? 
ATOM   2130 C  CB    . VAL   B 1 109 ? 10.737  4.834   -7.872  1.000 49.438  0 109 VAL   B CB    1 ? 
ATOM   2131 C  CG1   . VAL   B 1 109 ? 11.012  6.063   -8.716  1.000 45.112  0 109 VAL   B CG1   1 ? 
ATOM   2132 C  CG2   . VAL   B 1 109 ? 10.076  5.237   -6.551  1.000 50.975  0 109 VAL   B CG2   1 ? 
ATOM   2133 N  N     . LEU   B 1 110 ? 9.886   3.512   -11.065 1.000 49.548  0 110 LEU   B N     1 ? 
ATOM   2134 C  CA    . LEU   B 1 110 ? 10.374  3.114   -12.375 1.000 52.426  0 110 LEU   B CA    1 ? 
ATOM   2135 C  C     . LEU   B 1 110 ? 10.569  4.343   -13.246 1.000 46.471  0 110 LEU   B C     1 ? 
ATOM   2136 O  O     . LEU   B 1 110 ? 9.601   5.042   -13.537 1.000 52.087  0 110 LEU   B O     1 ? 
ATOM   2137 C  CB    . LEU   B 1 110 ? 9.287   2.227   -12.981 1.000 54.272  0 110 LEU   B CB    1 ? 
ATOM   2138 C  CG    . LEU   B 1 110 ? 9.718   1.156   -13.994 1.000 61.425  0 110 LEU   B CG    1 ? 
ATOM   2139 C  CD1   . LEU   B 1 110 ? 8.823   1.230   -15.211 1.000 61.175  0 110 LEU   B CD1   1 ? 
ATOM   2140 C  CD2   . LEU   B 1 110 ? 11.159  1.139   -14.414 1.000 59.408  0 110 LEU   B CD2   1 ? 
ATOM   2141 N  N     . LEU   B 1 111 ? 11.800  4.579   -13.682 1.000 48.621  0 111 LEU   B N     1 ? 
ATOM   2142 C  CA    . LEU   B 1 111 ? 12.056  5.565   -14.719 1.000 51.828  0 111 LEU   B CA    1 ? 
ATOM   2143 C  C     . LEU   B 1 111 ? 12.048  4.897   -16.095 1.000 54.577  0 111 LEU   B C     1 ? 
ATOM   2144 O  O     . LEU   B 1 111 ? 12.539  3.781   -16.275 1.000 49.910  0 111 LEU   B O     1 ? 
ATOM   2145 C  CB    . LEU   B 1 111 ? 13.393  6.268   -14.491 1.000 54.443  0 111 LEU   B CB    1 ? 
ATOM   2146 C  CG    . LEU   B 1 111 ? 13.619  6.922   -13.132 1.000 53.846  0 111 LEU   B CG    1 ? 
ATOM   2147 C  CD1   . LEU   B 1 111 ? 14.979  7.596   -13.144 1.000 53.350  0 111 LEU   B CD1   1 ? 
ATOM   2148 C  CD2   . LEU   B 1 111 ? 12.522  7.921   -12.845 1.000 57.816  0 111 LEU   B CD2   1 ? 
ATOM   2149 N  N     . VAL   B 1 112 ? 11.535  5.647   -17.080 1.000 61.589  0 112 VAL   B N     1 ? 
ATOM   2150 C  CA    . VAL   B 1 112 ? 11.510  5.241   -18.474 1.000 58.817  0 112 VAL   B CA    1 ? 
ATOM   2151 C  C     . VAL   B 1 112 ? 12.167  6.328   -19.313 1.000 50.649  0 112 VAL   B C     1 ? 
ATOM   2152 O  O     . VAL   B 1 112 ? 11.689  7.454   -19.340 1.000 52.166  0 112 VAL   B O     1 ? 
ATOM   2153 C  CB    . VAL   B 1 112 ? 10.098  4.998   -19.033 1.000 65.705  0 112 VAL   B CB    1 ? 
ATOM   2154 C  CG1   . VAL   B 1 112 ? 10.176  4.195   -20.330 1.000 70.061  0 112 VAL   B CG1   1 ? 
ATOM   2155 C  CG2   . VAL   B 1 112 ? 9.201   4.313   -18.028 1.000 76.227  0 112 VAL   B CG2   1 ? 
ATOM   2156 N  N     . ILE   B 1 113 ? 13.185  5.943   -20.079 1.000 50.887  0 113 ILE   B N     1 ? 
ATOM   2157 C  CA    . ILE   B 1 113 ? 13.931  6.860   -20.919 1.000 57.976  0 113 ILE   B CA    1 ? 
ATOM   2158 C  C     . ILE   B 1 113 ? 13.751  6.455   -22.388 1.000 58.705  0 113 ILE   B C     1 ? 
ATOM   2159 O  O     . ILE   B 1 113 ? 13.850  5.281   -22.741 1.000 53.463  0 113 ILE   B O     1 ? 
ATOM   2160 C  CB    . ILE   B 1 113 ? 15.399  6.845   -20.487 1.000 52.993  0 113 ILE   B CB    1 ? 
ATOM   2161 C  CG1   . ILE   B 1 113 ? 15.544  7.294   -19.031 1.000 53.726  0 113 ILE   B CG1   1 ? 
ATOM   2162 C  CG2   . ILE   B 1 113 ? 16.260  7.666   -21.442 1.000 57.012  0 113 ILE   B CG2   1 ? 
ATOM   2163 C  CD1   . ILE   B 1 113 ? 16.967  7.340   -18.509 1.000 51.936  0 113 ILE   B CD1   1 ? 
ATOM   2164 N  N     . PRO   B 1 114 ? 13.475  7.419   -23.287 1.000 63.463  0 114 PRO   B N     1 ? 
ATOM   2165 C  CA    . PRO   B 1 114 ? 13.429  7.129   -24.724 1.000 64.038  0 114 PRO   B CA    1 ? 
ATOM   2166 C  C     . PRO   B 1 114 ? 14.678  6.369   -25.143 1.000 62.132  0 114 PRO   B C     1 ? 
ATOM   2167 O  O     . PRO   B 1 114 ? 15.768  6.646   -24.645 1.000 56.778  0 114 PRO   B O     1 ? 
ATOM   2168 C  CB    . PRO   B 1 114 ? 13.326  8.500   -25.385 1.000 63.715  0 114 PRO   B CB    1 ? 
ATOM   2169 C  CG    . PRO   B 1 114 ? 12.637  9.359   -24.314 1.000 70.083  0 114 PRO   B CG    1 ? 
ATOM   2170 C  CD    . PRO   B 1 114 ? 13.169  8.830   -22.974 1.000 63.046  0 114 PRO   B CD    1 ? 
ATOM   2171 N  N     . ASP   B 1 115 ? 14.483  5.394   -26.036 1.000 61.678  0 115 ASP   B N     1 ? 
ATOM   2172 C  CA    . ASP   B 1 115 ? 15.561  4.532   -26.490 1.000 69.957  0 115 ASP   B CA    1 ? 
ATOM   2173 C  C     . ASP   B 1 115 ? 16.699  5.374   -27.043 1.000 58.475  0 115 ASP   B C     1 ? 
ATOM   2174 O  O     . ASP   B 1 115 ? 17.854  5.062   -26.791 1.000 60.884  0 115 ASP   B O     1 ? 
ATOM   2175 C  CB    . ASP   B 1 115 ? 15.092  3.489   -27.501 1.000 69.783  0 115 ASP   B CB    1 ? 
ATOM   2176 C  CG    . ASP   B 1 115 ? 14.184  2.405   -26.931 1.000 76.062  0 115 ASP   B CG    1 ? 
ATOM   2177 O  OD1   . ASP   B 1 115 ? 13.054  2.764   -26.506 1.000 66.984  0 115 ASP   B OD1   1 ? 
ATOM   2178 O  OD2   . ASP   B 1 115 ? 14.622  1.216   -26.903 1.000 68.839  0 115 ASP   B OD2   1 ? 
ATOM   2179 N  N     . GLU   B 1 116 ? 16.371  6.452   -27.761 1.000 56.417  0 116 GLU   B N     1 ? 
ATOM   2180 C  CA    . GLU   B 1 116 ? 17.399  7.302   -28.365 1.000 68.560  0 116 GLU   B CA    1 ? 
ATOM   2181 C  C     . GLU   B 1 116 ? 18.288  7.968   -27.295 1.000 70.439  0 116 GLU   B C     1 ? 
ATOM   2182 O  O     . GLU   B 1 116 ? 19.405  8.408   -27.582 1.000 63.286  0 116 GLU   B O     1 ? 
ATOM   2183 C  CB    . GLU   B 1 116 ? 16.798  8.332   -29.341 1.000 67.509  0 116 GLU   B CB    1 ? 
ATOM   2184 C  CG    . GLU   B 1 116 ? 15.582  9.100   -28.814 1.000 72.416  0 116 GLU   B CG    1 ? 
ATOM   2185 C  CD    . GLU   B 1 116 ? 14.194  8.460   -28.982 1.000 86.922  0 116 GLU   B CD    1 ? 
ATOM   2186 O  OE1   . GLU   B 1 116 ? 13.956  7.215   -28.784 1.000 73.658  0 116 GLU   B OE1   1 ? 
ATOM   2187 O  OE2   . GLU   B 1 116 ? 13.298  9.293   -29.264 1.000 74.476  0 116 GLU   B OE2   1 ? 
ATOM   2188 N  N     . ASP   B 1 117 ? 17.799  8.049   -26.049 1.000 71.165  0 117 ASP   B N     1 ? 
ATOM   2189 C  CA    . ASP   B 1 117 ? 18.528  8.729   -24.992 1.000 64.988  0 117 ASP   B CA    1 ? 
ATOM   2190 C  C     . ASP   B 1 117 ? 19.048  7.760   -23.937 1.000 61.063  0 117 ASP   B C     1 ? 
ATOM   2191 O  O     . ASP   B 1 117 ? 19.835  8.171   -23.090 1.000 60.389  0 117 ASP   B O     1 ? 
ATOM   2192 C  CB    . ASP   B 1 117 ? 17.673  9.801   -24.334 1.000 69.686  0 117 ASP   B CB    1 ? 
ATOM   2193 C  CG    . ASP   B 1 117 ? 17.099  10.857  -25.258 1.000 64.991  0 117 ASP   B CG    1 ? 
ATOM   2194 O  OD1   . ASP   B 1 117 ? 17.842  11.257  -26.175 1.000 65.347  0 117 ASP   B OD1   1 ? 
ATOM   2195 O  OD2   . ASP   B 1 117 ? 15.931  11.275  -25.024 1.000 65.040  0 117 ASP   B OD2   1 ? 
ATOM   2196 N  N     . TYR   B 1 118 ? 18.622  6.489   -23.972 1.000 62.353  0 118 TYR   B N     1 ? 
ATOM   2197 C  CA    . TYR   B 1 118 ? 19.015  5.562   -22.923 1.000 61.740  0 118 TYR   B CA    1 ? 
ATOM   2198 C  C     . TYR   B 1 118 ? 20.534  5.424   -22.954 1.000 60.558  0 118 TYR   B C     1 ? 
ATOM   2199 O  O     . TYR   B 1 118 ? 21.100  5.116   -23.990 1.000 61.040  0 118 TYR   B O     1 ? 
ATOM   2200 C  CB    . TYR   B 1 118 ? 18.345  4.190   -23.037 1.000 59.472  0 118 TYR   B CB    1 ? 
ATOM   2201 C  CG    . TYR   B 1 118 ? 18.478  3.325   -21.788 1.000 66.405  0 118 TYR   B CG    1 ? 
ATOM   2202 C  CD1   . TYR   B 1 118 ? 19.585  2.507   -21.584 1.000 70.056  0 118 TYR   B CD1   1 ? 
ATOM   2203 C  CD2   . TYR   B 1 118 ? 17.472  3.293   -20.821 1.000 70.851  0 118 TYR   B CD2   1 ? 
ATOM   2204 C  CE1   . TYR   B 1 118 ? 19.694  1.701   -20.456 1.000 62.963  0 118 TYR   B CE1   1 ? 
ATOM   2205 C  CE2   . TYR   B 1 118 ? 17.584  2.510   -19.680 1.000 68.693  0 118 TYR   B CE2   1 ? 
ATOM   2206 C  CZ    . TYR   B 1 118 ? 18.705  1.716   -19.487 1.000 59.169  0 118 TYR   B CZ    1 ? 
ATOM   2207 O  OH    . TYR   B 1 118 ? 18.804  0.941   -18.345 1.000 58.929  0 118 TYR   B OH    1 ? 
ATOM   2208 N  N     . GLY   B 1 119 ? 21.185  5.659   -21.814 1.000 61.418  0 119 GLY   B N     1 ? 
ATOM   2209 C  CA    . GLY   B 1 119 ? 22.639  5.655   -21.692 1.000 59.260  0 119 GLY   B CA    1 ? 
ATOM   2210 C  C     . GLY   B 1 119 ? 23.222  7.039   -21.360 1.000 56.838  0 119 GLY   B C     1 ? 
ATOM   2211 O  O     . GLY   B 1 119 ? 24.323  7.144   -20.829 1.000 58.637  0 119 GLY   B O     1 ? 
ATOM   2212 N  N     . LYS   B 1 120 ? 22.504  8.111   -21.714 1.000 54.483  0 120 LYS   B N     1 ? 
ATOM   2213 C  CA    . LYS   B 1 120 ? 22.978  9.462   -21.456 1.000 60.805  0 120 LYS   B CA    1 ? 
ATOM   2214 C  C     . LYS   B 1 120 ? 22.984  9.724   -19.948 1.000 56.945  0 120 LYS   B C     1 ? 
ATOM   2215 O  O     . LYS   B 1 120 ? 22.250  9.100   -19.199 1.000 52.516  0 120 LYS   B O     1 ? 
ATOM   2216 C  CB    . LYS   B 1 120 ? 22.107  10.514  -22.151 1.000 68.035  0 120 LYS   B CB    1 ? 
ATOM   2217 C  CG    . LYS   B 1 120 ? 22.130  10.474  -23.667 1.000 76.251  0 120 LYS   B CG    1 ? 
ATOM   2218 C  CD    . LYS   B 1 120 ? 21.522  11.722  -24.291 1.000 75.878  0 120 LYS   B CD    1 ? 
ATOM   2219 C  CE    . LYS   B 1 120 ? 21.105  11.505  -25.715 1.000 76.198  0 120 LYS   B CE    1 ? 
ATOM   2220 N  NZ    . LYS   B 1 120 ? 20.322  12.626  -26.247 1.000 73.671  0 120 LYS   B NZ    1 ? 
ATOM   2221 N  N     . PRO   B 1 121 ? 23.821  10.654  -19.456 1.000 53.855  0 121 PRO   B N     1 ? 
ATOM   2222 C  CA    . PRO   B 1 121 ? 23.992  10.813  -18.015 1.000 58.330  0 121 PRO   B CA    1 ? 
ATOM   2223 C  C     . PRO   B 1 121 ? 22.731  11.365  -17.368 1.000 54.261  0 121 PRO   B C     1 ? 
ATOM   2224 O  O     . PRO   B 1 121 ? 22.045  12.179  -17.965 1.000 53.726  0 121 PRO   B O     1 ? 
ATOM   2225 C  CB    . PRO   B 1 121 ? 25.215  11.746  -17.849 1.000 62.295  0 121 PRO   B CB    1 ? 
ATOM   2226 C  CG    . PRO   B 1 121 ? 25.819  11.874  -19.261 1.000 65.162  0 121 PRO   B CG    1 ? 
ATOM   2227 C  CD    . PRO   B 1 121 ? 24.698  11.546  -20.246 1.000 57.491  0 121 PRO   B CD    1 ? 
ATOM   2228 N  N     . ILE   B 1 122 ? 22.440  10.881  -16.159 1.000 56.089  0 122 ILE   B N     1 ? 
ATOM   2229 C  CA    . ILE   B 1 122 ? 21.330  11.372  -15.358 1.000 51.479  0 122 ILE   B CA    1 ? 
ATOM   2230 C  C     . ILE   B 1 122 ? 21.858  11.735  -13.976 1.000 47.548  0 122 ILE   B C     1 ? 
ATOM   2231 O  O     . ILE   B 1 122 ? 22.866  11.224  -13.493 1.000 50.200  0 122 ILE   B O     1 ? 
ATOM   2232 C  CB    . ILE   B 1 122 ? 20.211  10.325  -15.253 1.000 51.168  0 122 ILE   B CB    1 ? 
ATOM   2233 C  CG1   . ILE   B 1 122 ? 20.618  9.137   -14.369 1.000 50.691  0 122 ILE   B CG1   1 ? 
ATOM   2234 C  CG2   . ILE   B 1 122 ? 19.755  9.856   -16.641 1.000 59.345  0 122 ILE   B CG2   1 ? 
ATOM   2235 C  CD1   . ILE   B 1 122 ? 19.512  8.110   -14.187 1.000 51.576  0 122 ILE   B CD1   1 ? 
ATOM   2236 N  N     . ASN   B 1 123 ? 21.152  12.653  -13.347 1.000 49.145  0 123 ASN   B N     1 ? 
ATOM   2237 C  CA    . ASN   B 1 123 ? 21.456  13.076  -12.002 1.000 46.473  0 123 ASN   B CA    1 ? 
ATOM   2238 C  C     . ASN   B 1 123 ? 21.565  11.869  -11.060 1.000 46.188  0 123 ASN   B C     1 ? 
ATOM   2239 O  O     . ASN   B 1 123 ? 20.779  10.941  -11.118 1.000 47.751  0 123 ASN   B O     1 ? 
ATOM   2240 C  CB    . ASN   B 1 123 ? 20.388  14.034  -11.519 1.000 51.891  0 123 ASN   B CB    1 ? 
ATOM   2241 C  CG    . ASN   B 1 123 ? 20.849  14.785  -10.299 1.000 55.484  0 123 ASN   B CG    1 ? 
ATOM   2242 O  OD1   . ASN   B 1 123 ? 20.875  14.203  -9.211  1.000 53.263  0 123 ASN   B OD1   1 ? 
ATOM   2243 N  ND2   . ASN   B 1 123 ? 21.241  16.043  -10.481 1.000 51.219  0 123 ASN   B ND2   1 ? 
ATOM   2244 N  N     . LEU   B 1 124 ? 22.588  11.902  -10.213 1.000 49.268  0 124 LEU   B N     1 ? 
ATOM   2245 C  CA    . LEU   B 1 124 ? 22.846  10.915  -9.179  1.000 55.074  0 124 LEU   B CA    1 ? 
ATOM   2246 C  C     . LEU   B 1 124 ? 21.602  10.629  -8.365  1.000 50.845  0 124 LEU   B C     1 ? 
ATOM   2247 O  O     . LEU   B 1 124 ? 21.346  9.470   -8.065  1.000 51.784  0 124 LEU   B O     1 ? 
ATOM   2248 C  CB    . LEU   B 1 124 ? 23.968  11.390  -8.257  1.000 50.012  0 124 LEU   B CB    1 ? 
ATOM   2249 C  CG    . LEU   B 1 124 ? 24.267  10.485  -7.064  1.000 52.494  0 124 LEU   B CG    1 ? 
ATOM   2250 C  CD1   . LEU   B 1 124 ? 24.856  9.197   -7.537  1.000 52.901  0 124 LEU   B CD1   1 ? 
ATOM   2251 C  CD2   . LEU   B 1 124 ? 25.211  11.169  -6.082  1.000 54.884  0 124 LEU   B CD2   1 ? 
ATOM   2252 N  N     . MET   B 1 125 ? 20.885  11.687  -7.963  1.000 49.701  0 125 MET   B N     1 ? 
ATOM   2253 C  CA    . MET   B 1 125 ? 19.742  11.504  -7.089  1.000 47.257  0 125 MET   B CA    1 ? 
ATOM   2254 C  C     . MET   B 1 125 ? 18.612  10.808  -7.836  1.000 50.040  0 125 MET   B C     1 ? 
ATOM   2255 O  O     . MET   B 1 125 ? 17.846  10.082  -7.217  1.000 46.645  0 125 MET   B O     1 ? 
ATOM   2256 C  CB    . MET   B 1 125 ? 19.252  12.800  -6.442  1.000 47.135  0 125 MET   B CB    1 ? 
ATOM   2257 C  CG    . MET   B 1 125 ? 20.370  13.654  -5.866  1.000 46.730  0 125 MET   B CG    1 ? 
ATOM   2258 S  SD    . MET   B 1 125 ? 21.519  12.722  -4.832  1.000 49.755  0 125 MET   B SD    1 ? 
ATOM   2259 C  CE    . MET   B 1 125 ? 20.538  12.549  -3.338  1.000 48.844  0 125 MET   B CE    1 ? 
ATOM   2260 N  N     . SER   B 1 126 ? 18.524  11.002  -9.154  1.000 46.777  0 126 SER   B N     1 ? 
ATOM   2261 C  CA    . SER   B 1 126 ? 17.560  10.277  -9.965  1.000 48.303  0 126 SER   B CA    1 ? 
ATOM   2262 C  C     . SER   B 1 126 ? 17.941  8.798   -10.055 1.000 47.691  0 126 SER   B C     1 ? 
ATOM   2263 O  O     . SER   B 1 126 ? 17.128  7.894   -9.894  1.000 47.840  0 126 SER   B O     1 ? 
ATOM   2264 C  CB    . SER   B 1 126 ? 17.489  10.895  -11.316 1.000 49.187  0 126 SER   B CB    1 ? 
ATOM   2265 O  OG    . SER   B 1 126 ? 16.906  12.179  -11.233 1.000 44.846  0 126 SER   B OG    1 ? 
ATOM   2266 N  N     . TRP   B 1 127 ? 19.218  8.572   -10.288 1.000 49.304  0 127 TRP   B N     1 ? 
ATOM   2267 C  CA    . TRP   B 1 127 ? 19.779  7.243   -10.326 1.000 53.915  0 127 TRP   B CA    1 ? 
ATOM   2268 C  C     . TRP   B 1 127 ? 19.469  6.499   -9.029  1.000 55.423  0 127 TRP   B C     1 ? 
ATOM   2269 O  O     . TRP   B 1 127 ? 19.088  5.331   -9.045  1.000 53.763  0 127 TRP   B O     1 ? 
ATOM   2270 C  CB    . TRP   B 1 127 ? 21.286  7.399   -10.578 1.000 54.238  0 127 TRP   B CB    1 ? 
ATOM   2271 C  CG    . TRP   B 1 127 ? 22.055  6.112   -10.482 1.000 59.030  0 127 TRP   B CG    1 ? 
ATOM   2272 C  CD1   . TRP   B 1 127 ? 22.331  5.248   -11.496 1.000 63.350  0 127 TRP   B CD1   1 ? 
ATOM   2273 C  CD2   . TRP   B 1 127 ? 22.653  5.554   -9.297  1.000 56.349  0 127 TRP   B CD2   1 ? 
ATOM   2274 N  NE1   . TRP   B 1 127 ? 23.053  4.189   -11.026 1.000 64.704  0 127 TRP   B NE1   1 ? 
ATOM   2275 C  CE2   . TRP   B 1 127 ? 23.262  4.348   -9.682  1.000 61.679  0 127 TRP   B CE2   1 ? 
ATOM   2276 C  CE3   . TRP   B 1 127 ? 22.721  5.940   -7.960  1.000 55.981  0 127 TRP   B CE3   1 ? 
ATOM   2277 C  CZ2   . TRP   B 1 127 ? 23.923  3.535   -8.770  1.000 53.742  0 127 TRP   B CZ2   1 ? 
ATOM   2278 C  CZ3   . TRP   B 1 127 ? 23.382  5.140   -7.061  1.000 54.765  0 127 TRP   B CZ3   1 ? 
ATOM   2279 C  CH2   . TRP   B 1 127 ? 23.975  3.949   -7.463  1.000 58.246  0 127 TRP   B CH2   1 ? 
ATOM   2280 N  N     . GLY   B 1 128 ? 19.623  7.206   -7.906  1.000 52.833  0 128 GLY   B N     1 ? 
ATOM   2281 C  CA    . GLY   B 1 128 ? 19.486  6.625   -6.583  1.000 50.646  0 128 GLY   B CA    1 ? 
ATOM   2282 C  C     . GLY   B 1 128 ? 18.026  6.431   -6.159  1.000 49.408  0 128 GLY   B C     1 ? 
ATOM   2283 O  O     . GLY   B 1 128 ? 17.704  5.405   -5.579  1.000 53.384  0 128 GLY   B O     1 ? 
ATOM   2284 N  N     . VAL   B 1 129 ? 17.126  7.389   -6.427  1.000 52.104  0 129 VAL   B N     1 ? 
ATOM   2285 C  CA    . VAL   B 1 129 ? 15.739  7.218   -5.993  1.000 56.441  0 129 VAL   B CA    1 ? 
ATOM   2286 C  C     . VAL   B 1 129 ? 15.129  6.023   -6.712  1.000 49.803  0 129 VAL   B C     1 ? 
ATOM   2287 O  O     . VAL   B 1 129 ? 14.133  5.495   -6.242  1.000 48.832  0 129 VAL   B O     1 ? 
ATOM   2288 C  CB    . VAL   B 1 129 ? 14.666  8.293   -6.260  1.000 48.508  0 129 VAL   B CB    1 ? 
ATOM   2289 C  CG1   . VAL   B 1 129 ? 14.286  9.068   -5.037  1.000 55.518  0 129 VAL   B CG1   1 ? 
ATOM   2290 C  CG2   . VAL   B 1 129 ? 14.942  9.090   -7.513  1.000 50.299  0 129 VAL   B CG2   1 ? 
ATOM   2291 N  N     . SER   B 1 130 ? 15.532  5.831   -7.966  1.000 46.245  0 130 SER   B N     1 ? 
ATOM   2292 C  CA    . SER   B 1 130 ? 14.868  4.887   -8.835  1.000 52.899  0 130 SER   B CA    1 ? 
ATOM   2293 C  C     . SER   B 1 130 ? 15.124  3.486   -8.285  1.000 45.889  0 130 SER   B C     1 ? 
ATOM   2294 O  O     . SER   B 1 130 ? 16.204  3.194   -7.780  1.000 49.099  0 130 SER   B O     1 ? 
ATOM   2295 C  CB    . SER   B 1 130 ? 15.348  5.048   -10.250 1.000 49.063  0 130 SER   B CB    1 ? 
ATOM   2296 O  OG    . SER   B 1 130 ? 16.684  4.561   -10.352 1.000 56.566  0 130 SER   B OG    1 ? 
ATOM   2297 N  N     . ASP   B 1 131 ? 14.109  2.631   -8.384  1.000 50.608  0 131 ASP   B N     1 ? 
ATOM   2298 C  CA    . ASP   B 1 131 ? 14.321  1.209   -8.173  1.000 53.719  0 131 ASP   B CA    1 ? 
ATOM   2299 C  C     . ASP   B 1 131 ? 14.790  0.517   -9.457  1.000 55.621  0 131 ASP   B C     1 ? 
ATOM   2300 O  O     . ASP   B 1 131 ? 15.428  -0.531  -9.415  1.000 58.636  0 131 ASP   B O     1 ? 
ATOM   2301 C  CB    . ASP   B 1 131 ? 13.060  0.585   -7.624  1.000 55.318  0 131 ASP   B CB    1 ? 
ATOM   2302 C  CG    . ASP   B 1 131 ? 12.700  1.045   -6.226  1.000 50.156  0 131 ASP   B CG    1 ? 
ATOM   2303 O  OD1   . ASP   B 1 131 ? 13.553  0.891   -5.340  1.000 51.901  0 131 ASP   B OD1   1 ? 
ATOM   2304 O  OD2   . ASP   B 1 131 ? 11.556  1.546   -6.052  1.000 58.826  0 131 ASP   B OD2   1 ? 
ATOM   2305 N  N     . ASN   B 1 132 ? 14.529  1.138   -10.605 1.000 52.648  0 132 ASN   B N     1 ? 
ATOM   2306 C  CA    . ASN   B 1 132 ? 14.926  0.565   -11.872 1.000 54.625  0 132 ASN   B CA    1 ? 
ATOM   2307 C  C     . ASN   B 1 132 ? 14.784  1.642   -12.938 1.000 54.578  0 132 ASN   B C     1 ? 
ATOM   2308 O  O     . ASN   B 1 132 ? 13.960  2.553   -12.795 1.000 57.475  0 132 ASN   B O     1 ? 
ATOM   2309 C  CB    . ASN   B 1 132 ? 14.061  -0.664  -12.149 1.000 55.375  0 132 ASN   B CB    1 ? 
ATOM   2310 C  CG    . ASN   B 1 132 ? 14.511  -1.519  -13.310 1.000 57.709  0 132 ASN   B CG    1 ? 
ATOM   2311 O  OD1   . ASN   B 1 132 ? 13.760  -2.410  -13.731 1.000 63.392  0 132 ASN   B OD1   1 ? 
ATOM   2312 N  ND2   . ASN   B 1 132 ? 15.724  -1.335  -13.803 1.000 50.016  0 132 ASN   B ND2   1 ? 
ATOM   2313 N  N     . VAL   B 1 133 ? 15.574  1.532   -14.010 1.000 56.485  0 133 VAL   B N     1 ? 
ATOM   2314 C  CA    . VAL   B 1 133 ? 15.368  2.406   -15.151 1.000 57.716  0 133 VAL   B CA    1 ? 
ATOM   2315 C  C     . VAL   B 1 133 ? 15.522  1.628   -16.455 1.000 56.689  0 133 VAL   B C     1 ? 
ATOM   2316 O  O     . VAL   B 1 133 ? 16.503  0.932   -16.680 1.000 58.973  0 133 VAL   B O     1 ? 
ATOM   2317 C  CB    . VAL   B 1 133 ? 16.198  3.710   -15.056 1.000 61.152  0 133 VAL   B CB    1 ? 
ATOM   2318 C  CG1   . VAL   B 1 133 ? 17.189  3.711   -13.907 1.000 57.793  0 133 VAL   B CG1   1 ? 
ATOM   2319 C  CG2   . VAL   B 1 133 ? 16.822  4.172   -16.365 1.000 59.942  0 133 VAL   B CG2   1 ? 
ATOM   2320 N  N     . ILE   B 1 134 ? 14.494  1.761   -17.291 1.000 56.897  0 134 ILE   B N     1 ? 
ATOM   2321 C  CA    . ILE   B 1 134 ? 14.327  0.959   -18.490 1.000 59.872  0 134 ILE   B CA    1 ? 
ATOM   2322 C  C     . ILE   B 1 134 ? 14.175  1.890   -19.692 1.000 62.750  0 134 ILE   B C     1 ? 
ATOM   2323 O  O     . ILE   B 1 134 ? 13.989  3.101   -19.541 1.000 54.774  0 134 ILE   B O     1 ? 
ATOM   2324 C  CB    . ILE   B 1 134 ? 13.093  0.052   -18.349 1.000 54.522  0 134 ILE   B CB    1 ? 
ATOM   2325 C  CG1   . ILE   B 1 134 ? 11.822  0.881   -18.207 1.000 55.986  0 134 ILE   B CG1   1 ? 
ATOM   2326 C  CG2   . ILE   B 1 134 ? 13.262  -0.911  -17.180 1.000 56.734  0 134 ILE   B CG2   1 ? 
ATOM   2327 C  CD1   . ILE   B 1 134 ? 10.543  0.116   -18.514 1.000 59.592  0 134 ILE   B CD1   1 ? 
ATOM   2328 N  N     . LYS   B 1 135 ? 14.189  1.302   -20.888 1.000 63.156  0 135 LYS   B N     1 ? 
ATOM   2329 C  CA    . LYS   B 1 135 ? 14.007  2.097   -22.087 1.000 70.525  0 135 LYS   B CA    1 ? 
ATOM   2330 C  C     . LYS   B 1 135 ? 12.542  2.038   -22.493 1.000 57.666  0 135 LYS   B C     1 ? 
ATOM   2331 O  O     . LYS   B 1 135 ? 11.809  1.138   -22.101 1.000 63.008  0 135 LYS   B O     1 ? 
ATOM   2332 C  CB    . LYS   B 1 135 ? 15.050  1.734   -23.144 1.000 83.676  0 135 LYS   B CB    1 ? 
ATOM   2333 C  CG    . LYS   B 1 135 ? 15.138  0.313   -23.587 1.000 91.977  0 135 LYS   B CG    1 ? 
ATOM   2334 C  CD    . LYS   B 1 135 ? 16.362  0.076   -24.467 1.000 89.937  0 135 LYS   B CD    1 ? 
ATOM   2335 C  CE    . LYS   B 1 135 ? 17.583  -0.191  -23.659 1.000 94.325  0 135 LYS   B CE    1 ? 
ATOM   2336 N  NZ    . LYS   B 1 135 ? 18.662  -0.723  -24.491 1.000 96.837  0 135 LYS   B NZ    1 ? 
ATOM   2337 N  N     . MET   B 1 136 ? 12.105  3.063   -23.219 1.000 56.282  0 136 MET   B N     1 ? 
ATOM   2338 C  CA    . MET   B 1 136 ? 10.715  3.176   -23.630 1.000 57.942  0 136 MET   B CA    1 ? 
ATOM   2339 C  C     . MET   B 1 136 ? 10.221  1.882   -24.273 1.000 54.136  0 136 MET   B C     1 ? 
ATOM   2340 O  O     . MET   B 1 136 ? 9.084   1.496   -24.038 1.000 54.732  0 136 MET   B O     1 ? 
ATOM   2341 C  CB    . MET   B 1 136 ? 10.544  4.335   -24.612 1.000 58.880  0 136 MET   B CB    1 ? 
ATOM   2342 C  CG    . MET   B 1 136 ? 9.101   4.629   -24.958 1.000 69.317  0 136 MET   B CG    1 ? 
ATOM   2343 S  SD    . MET   B 1 136 ? 8.154   5.308   -23.588 1.000 64.382  0 136 MET   B SD    1 ? 
ATOM   2344 C  CE    . MET   B 1 136 ? 9.039   6.871   -23.484 1.000 66.897  0 136 MET   B CE    1 ? 
ATOM   2345 N  N     . SER   B 1 137 ? 11.087  1.211   -25.040 1.000 56.501  0 137 SER   B N     1 ? 
ATOM   2346 C  CA    . SER   B 1 137 ? 10.695  0.045   -25.814 1.000 66.960  0 137 SER   B CA    1 ? 
ATOM   2347 C  C     . SER   B 1 137 ? 10.443  -1.160  -24.915 1.000 66.187  0 137 SER   B C     1 ? 
ATOM   2348 O  O     . SER   B 1 137 ? 9.870   -2.132  -25.387 1.000 73.141  0 137 SER   B O     1 ? 
ATOM   2349 C  CB    . SER   B 1 137 ? 11.722  -0.287  -26.887 1.000 62.400  0 137 SER   B CB    1 ? 
ATOM   2350 O  OG    . SER   B 1 137 ? 12.939  -0.753  -26.312 1.000 66.244  0 137 SER   B OG    1 ? 
ATOM   2351 N  N     . GLN   B 1 138 ? 10.849  -1.093  -23.634 1.000 67.811  0 138 GLN   B N     1 ? 
ATOM   2352 C  CA    . GLN   B 1 138 ? 10.635  -2.196  -22.701 1.000 61.091  0 138 GLN   B CA    1 ? 
ATOM   2353 C  C     . GLN   B 1 138 ? 9.348   -1.999  -21.884 1.000 55.448  0 138 GLN   B C     1 ? 
ATOM   2354 O  O     . GLN   B 1 138 ? 8.919   -2.895  -21.153 1.000 59.531  0 138 GLN   B O     1 ? 
ATOM   2355 C  CB    . GLN   B 1 138 ? 11.825  -2.418  -21.766 1.000 59.111  0 138 GLN   B CB    1 ? 
ATOM   2356 C  CG    . GLN   B 1 138 ? 13.140  -2.791  -22.440 1.000 61.717  0 138 GLN   B CG    1 ? 
ATOM   2357 C  CD    . GLN   B 1 138 ? 14.334  -2.729  -21.502 1.000 71.041  0 138 GLN   B CD    1 ? 
ATOM   2358 O  OE1   . GLN   B 1 138 ? 14.712  -1.672  -20.982 1.000 60.608  0 138 GLN   B OE1   1 ? 
ATOM   2359 N  NE2   . GLN   B 1 138 ? 14.958  -3.871  -21.264 1.000 75.761  0 138 GLN   B NE2   1 ? 
ATOM   2360 N  N     . LEU   B 1 139 ? 8.705   -0.837  -22.000 1.000 51.532  0 139 LEU   B N     1 ? 
ATOM   2361 C  CA    . LEU   B 1 139 ? 7.610   -0.491  -21.102 1.000 54.804  0 139 LEU   B CA    1 ? 
ATOM   2362 C  C     . LEU   B 1 139 ? 6.377   -1.355  -21.363 1.000 63.453  0 139 LEU   B C     1 ? 
ATOM   2363 O  O     . LEU   B 1 139 ? 5.701   -1.747  -20.401 1.000 63.375  0 139 LEU   B O     1 ? 
ATOM   2364 C  CB    . LEU   B 1 139 ? 7.291   1.002   -21.227 1.000 56.486  0 139 LEU   B CB    1 ? 
ATOM   2365 C  CG    . LEU   B 1 139 ? 6.197   1.564   -20.306 1.000 58.188  0 139 LEU   B CG    1 ? 
ATOM   2366 C  CD1   . LEU   B 1 139 ? 6.384   1.192   -18.841 1.000 55.152  0 139 LEU   B CD1   1 ? 
ATOM   2367 C  CD2   . LEU   B 1 139 ? 6.142   3.076   -20.458 1.000 57.713  0 139 LEU   B CD2   1 ? 
ATOM   2368 N  N     . LYS   B 1 140 ? 6.073   -1.669  -22.641 1.000 67.885  0 140 LYS   B N     1 ? 
ATOM   2369 C  CA    . LYS   B 1 140 ? 4.842   -2.399  -22.970 1.000 73.023  0 140 LYS   B CA    1 ? 
ATOM   2370 C  C     . LYS   B 1 140 ? 4.851   -3.811  -22.370 1.000 59.683  0 140 LYS   B C     1 ? 
ATOM   2371 O  O     . LYS   B 1 140 ? 3.790   -4.376  -22.104 1.000 62.124  0 140 LYS   B O     1 ? 
ATOM   2372 C  CB    . LYS   B 1 140 ? 4.530   -2.495  -24.472 1.000 86.976  0 140 LYS   B CB    1 ? 
ATOM   2373 C  CG    . LYS   B 1 140 ? 5.514   -3.300  -25.338 1.000 101.712 0 140 LYS   B CG    1 ? 
ATOM   2374 C  CD    . LYS   B 1 140 ? 5.243   -3.327  -26.846 1.000 103.490 0 140 LYS   B CD    1 ? 
ATOM   2375 C  CE    . LYS   B 1 140 ? 5.902   -4.456  -27.611 1.000 90.077  0 140 LYS   B CE    1 ? 
ATOM   2376 N  N     . ASP   B 1 141 ? 6.047   -4.358  -22.108 1.000 58.080  0 141 ASP   B N     1 ? 
ATOM   2377 C  CA    . ASP   B 1 141 ? 6.180   -5.742  -21.691 1.000 65.920  0 141 ASP   B CA    1 ? 
ATOM   2378 C  C     . ASP   B 1 141 ? 6.678   -5.860  -20.257 1.000 69.155  0 141 ASP   B C     1 ? 
ATOM   2379 O  O     . ASP   B 1 141 ? 6.848   -6.969  -19.758 1.000 63.359  0 141 ASP   B O     1 ? 
ATOM   2380 C  CB    . ASP   B 1 141 ? 7.087   -6.504  -22.650 1.000 78.152  0 141 ASP   B CB    1 ? 
ATOM   2381 C  CG    . ASP   B 1 141 ? 6.569   -6.594  -24.084 1.000 87.725  0 141 ASP   B CG    1 ? 
ATOM   2382 O  OD1   . ASP   B 1 141 ? 5.344   -6.825  -24.270 1.000 73.609  0 141 ASP   B OD1   1 ? 
ATOM   2383 O  OD2   . ASP   B 1 141 ? 7.381   -6.418  -25.010 1.000 87.301  0 141 ASP   B OD2   1 ? 
ATOM   2384 N  N     . PHE   B 1 142 ? 6.915   -4.727  -19.594 1.000 72.160  0 142 PHE   B N     1 ? 
ATOM   2385 C  CA    . PHE   B 1 142 ? 7.371   -4.749  -18.212 1.000 74.565  0 142 PHE   B CA    1 ? 
ATOM   2386 C  C     . PHE   B 1 142 ? 6.336   -5.459  -17.341 1.000 60.699  0 142 PHE   B C     1 ? 
ATOM   2387 O  O     . PHE   B 1 142 ? 5.139   -5.135  -17.385 1.000 60.800  0 142 PHE   B O     1 ? 
ATOM   2388 C  CB    . PHE   B 1 142 ? 7.625   -3.322  -17.711 1.000 76.999  0 142 PHE   B CB    1 ? 
ATOM   2389 C  CG    . PHE   B 1 142 ? 8.391   -3.293  -16.401 1.000 66.921  0 142 PHE   B CG    1 ? 
ATOM   2390 C  CD1   . PHE   B 1 142 ? 9.779   -3.412  -16.387 1.000 63.264  0 142 PHE   B CD1   1 ? 
ATOM   2391 C  CD2   . PHE   B 1 142 ? 7.729   -3.174  -15.194 1.000 65.685  0 142 PHE   B CD2   1 ? 
ATOM   2392 C  CE1   . PHE   B 1 142 ? 10.482  -3.416  -15.200 1.000 66.796  0 142 PHE   B CE1   1 ? 
ATOM   2393 C  CE2   . PHE   B 1 142 ? 8.443   -3.185  -13.999 1.000 68.887  0 142 PHE   B CE2   1 ? 
ATOM   2394 C  CZ    . PHE   B 1 142 ? 9.814   -3.306  -14.003 1.000 67.524  0 142 PHE   B CZ    1 ? 
ATOM   2395 N  N     . ASN   B 1 143 ? 6.808   -6.414  -16.531 1.000 52.730  0 143 ASN   B N     1 ? 
ATOM   2396 C  CA    . ASN   B 1 143 ? 5.914   -7.122  -15.630 1.000 62.450  0 143 ASN   B CA    1 ? 
ATOM   2397 C  C     . ASN   B 1 143 ? 5.799   -6.362  -14.307 1.000 61.437  0 143 ASN   B C     1 ? 
ATOM   2398 O  O     . ASN   B 1 143 ? 6.657   -6.489  -13.451 1.000 56.074  0 143 ASN   B O     1 ? 
ATOM   2399 C  CB    . ASN   B 1 143 ? 6.387   -8.541  -15.348 1.000 54.098  0 143 ASN   B CB    1 ? 
ATOM   2400 C  CG    . ASN   B 1 143 ? 5.324   -9.307  -14.588 1.000 58.705  0 143 ASN   B CG    1 ? 
ATOM   2401 O  OD1   . ASN   B 1 143 ? 4.309   -8.726  -14.168 1.000 56.173  0 143 ASN   B OD1   1 ? 
ATOM   2402 N  ND2   . ASN   B 1 143 ? 5.539   -10.603 -14.387 1.000 62.108  0 143 ASN   B ND2   1 ? 
ATOM   2403 N  N     . PHE   B 1 144 ? 4.714   -5.610  -14.139 1.000 57.724  0 144 PHE   B N     1 ? 
ATOM   2404 C  CA    . PHE   B 1 144 ? 4.532   -4.780  -12.968 1.000 62.621  0 144 PHE   B CA    1 ? 
ATOM   2405 C  C     . PHE   B 1 144 ? 4.105   -5.602  -11.760 1.000 66.925  0 144 PHE   B C     1 ? 
ATOM   2406 O  O     . PHE   B 1 144 ? 4.070   -5.063  -10.649 1.000 64.015  0 144 PHE   B O     1 ? 
ATOM   2407 C  CB    . PHE   B 1 144 ? 3.517   -3.671  -13.240 1.000 56.685  0 144 PHE   B CB    1 ? 
ATOM   2408 C  CG    . PHE   B 1 144 ? 4.126   -2.559  -14.064 1.000 61.746  0 144 PHE   B CG    1 ? 
ATOM   2409 C  CD1   . PHE   B 1 144 ? 4.914   -1.589  -13.458 1.000 63.924  0 144 PHE   B CD1   1 ? 
ATOM   2410 C  CD2   . PHE   B 1 144 ? 3.923   -2.492  -15.428 1.000 61.965  0 144 PHE   B CD2   1 ? 
ATOM   2411 C  CE1   . PHE   B 1 144 ? 5.474   -0.571  -14.199 1.000 67.322  0 144 PHE   B CE1   1 ? 
ATOM   2412 C  CE2   . PHE   B 1 144 ? 4.482   -1.466  -16.163 1.000 71.006  0 144 PHE   B CE2   1 ? 
ATOM   2413 C  CZ    . PHE   B 1 144 ? 5.239   -0.496  -15.544 1.000 66.800  0 144 PHE   B CZ    1 ? 
ATOM   2414 N  N     . ASN   B 1 145 ? 3.810   -6.891  -11.957 1.000 64.407  0 145 ASN   B N     1 ? 
ATOM   2415 C  CA    . ASN   B 1 145 ? 3.481   -7.744  -10.820 1.000 63.392  0 145 ASN   B CA    1 ? 
ATOM   2416 C  C     . ASN   B 1 145 ? 4.747   -8.235  -10.125 1.000 57.397  0 145 ASN   B C     1 ? 
ATOM   2417 O  O     . ASN   B 1 145 ? 4.676   -8.632  -8.961  1.000 58.624  0 145 ASN   B O     1 ? 
ATOM   2418 C  CB    . ASN   B 1 145 ? 2.595   -8.927  -11.195 1.000 67.624  0 145 ASN   B CB    1 ? 
ATOM   2419 C  CG    . ASN   B 1 145 ? 1.245   -8.470  -11.688 1.000 69.900  0 145 ASN   B CG    1 ? 
ATOM   2420 O  OD1   . ASN   B 1 145 ? 0.550   -7.717  -10.997 1.000 68.389  0 145 ASN   B OD1   1 ? 
ATOM   2421 N  ND2   . ASN   B 1 145 ? 0.880   -8.862  -12.898 1.000 78.263  0 145 ASN   B ND2   1 ? 
ATOM   2422 N  N     . LYS   B 1 146 ? 5.882   -8.215  -10.841 1.000 56.485  0 146 LYS   B N     1 ? 
ATOM   2423 C  CA    . LYS   B 1 146 ? 7.167   -8.667  -10.325 1.000 64.333  0 146 LYS   B CA    1 ? 
ATOM   2424 C  C     . LYS   B 1 146 ? 8.224   -7.586  -10.574 1.000 64.270  0 146 LYS   B C     1 ? 
ATOM   2425 O  O     . LYS   B 1 146 ? 9.260   -7.811  -11.197 1.000 68.072  0 146 LYS   B O     1 ? 
ATOM   2426 C  CB    . LYS   B 1 146 ? 7.510   -10.036 -10.929 1.000 72.582  0 146 LYS   B CB    1 ? 
ATOM   2427 C  CG    . LYS   B 1 146 ? 6.614   -11.125 -10.340 1.000 86.143  0 146 LYS   B CG    1 ? 
ATOM   2428 C  CD    . LYS   B 1 146 ? 7.059   -12.567 -10.542 1.000 94.593  0 146 LYS   B CD    1 ? 
ATOM   2429 C  CE    . LYS   B 1 146 ? 6.704   -13.078 -11.892 1.000 99.808  0 146 LYS   B CE    1 ? 
ATOM   2430 N  NZ    . LYS   B 1 146 ? 6.544   -14.535 -11.848 1.000 106.420 0 146 LYS   B NZ    1 ? 
ATOM   2431 N  N     . PRO   B 1 147 ? 8.034   -6.371  -10.034 1.000 61.573  0 147 PRO   B N     1 ? 
ATOM   2432 C  CA    . PRO   B 1 147 ? 9.017   -5.306  -10.231 1.000 61.088  0 147 PRO   B CA    1 ? 
ATOM   2433 C  C     . PRO   B 1 147 ? 10.263  -5.608  -9.407  1.000 56.278  0 147 PRO   B C     1 ? 
ATOM   2434 O  O     . PRO   B 1 147 ? 10.148  -5.997  -8.254  1.000 59.994  0 147 PRO   B O     1 ? 
ATOM   2435 C  CB    . PRO   B 1 147 ? 8.237   -4.106  -9.719  1.000 66.625  0 147 PRO   B CB    1 ? 
ATOM   2436 C  CG    . PRO   B 1 147 ? 7.370   -4.670  -8.619  1.000 68.322  0 147 PRO   B CG    1 ? 
ATOM   2437 C  CD    . PRO   B 1 147 ? 6.927   -6.004  -9.139  1.000 61.235  0 147 PRO   B CD    1 ? 
ATOM   2438 N  N     . ARG   B 1 148 ? 11.440  -5.433  -10.007 1.000 54.438  0 148 ARG   B N     1 ? 
ATOM   2439 C  CA    . ARG   B 1 148 ? 12.707  -5.771  -9.373  1.000 58.376  0 148 ARG   B CA    1 ? 
ATOM   2440 C  C     . ARG   B 1 148 ? 13.639  -4.561  -9.381  1.000 52.717  0 148 ARG   B C     1 ? 
ATOM   2441 O  O     . ARG   B 1 148 ? 13.466  -3.637  -10.173 1.000 52.365  0 148 ARG   B O     1 ? 
ATOM   2442 C  CB    . ARG   B 1 148 ? 13.424  -6.909  -10.116 1.000 67.015  0 148 ARG   B CB    1 ? 
ATOM   2443 C  CG    . ARG   B 1 148 ? 12.716  -8.258  -10.204 1.000 76.065  0 148 ARG   B CG    1 ? 
ATOM   2444 C  CD    . ARG   B 1 148 ? 12.512  -8.956  -8.875  1.000 78.745  0 148 ARG   B CD    1 ? 
ATOM   2445 N  NE    . ARG   B 1 148 ? 11.520  -10.038 -8.966  1.000 89.798  0 148 ARG   B NE    1 ? 
ATOM   2446 C  CZ    . ARG   B 1 148 ? 10.324  -10.090 -8.362  1.000 103.216 0 148 ARG   B CZ    1 ? 
ATOM   2447 N  NH1   . ARG   B 1 148 ? 9.702   -11.255 -8.219  1.000 111.255 0 148 ARG   B NH1   1 ? 
ATOM   2448 N  NH2   . ARG   B 1 148 ? 9.773   -8.999  -7.841  1.000 98.383  0 148 ARG   B NH2   1 ? 
ATOM   2449 N  N     . PHE   B 1 149 ? 14.605  -4.577  -8.467  1.000 52.467  0 149 PHE   B N     1 ? 
ATOM   2450 C  CA    . PHE   B 1 149 ? 15.653  -3.580  -8.386  1.000 53.597  0 149 PHE   B CA    1 ? 
ATOM   2451 C  C     . PHE   B 1 149 ? 16.700  -3.833  -9.468  1.000 54.682  0 149 PHE   B C     1 ? 
ATOM   2452 O  O     . PHE   B 1 149 ? 17.225  -4.932  -9.538  1.000 61.978  0 149 PHE   B O     1 ? 
ATOM   2453 C  CB    . PHE   B 1 149 ? 16.380  -3.652  -7.031  1.000 54.530  0 149 PHE   B CB    1 ? 
ATOM   2454 C  CG    . PHE   B 1 149 ? 17.459  -2.585  -6.974  1.000 62.220  0 149 PHE   B CG    1 ? 
ATOM   2455 C  CD1   . PHE   B 1 149 ? 17.148  -1.278  -6.610  1.000 70.263  0 149 PHE   B CD1   1 ? 
ATOM   2456 C  CD2   . PHE   B 1 149 ? 18.759  -2.868  -7.392  1.000 66.340  0 149 PHE   B CD2   1 ? 
ATOM   2457 C  CE1   . PHE   B 1 149 ? 18.127  -0.293  -6.633  1.000 71.482  0 149 PHE   B CE1   1 ? 
ATOM   2458 C  CE2   . PHE   B 1 149 ? 19.738  -1.892  -7.392  1.000 67.233  0 149 PHE   B CE2   1 ? 
ATOM   2459 C  CZ    . PHE   B 1 149 ? 19.418  -0.606  -7.010  1.000 73.167  0 149 PHE   B CZ    1 ? 
ATOM   2460 N  N     . ASP   B 1 150 ? 17.082  -2.805  -10.233 1.000 53.097  0 150 ASP   B N     1 ? 
ATOM   2461 C  CA    . ASP   B 1 150 ? 18.267  -2.916  -11.069 1.000 59.853  0 150 ASP   B CA    1 ? 
ATOM   2462 C  C     . ASP   B 1 150 ? 18.911  -1.544  -11.255 1.000 58.484  0 150 ASP   B C     1 ? 
ATOM   2463 O  O     . ASP   B 1 150 ? 18.280  -0.532  -10.982 1.000 53.894  0 150 ASP   B O     1 ? 
ATOM   2464 C  CB    . ASP   B 1 150 ? 17.919  -3.536  -12.411 1.000 64.052  0 150 ASP   B CB    1 ? 
ATOM   2465 C  CG    . ASP   B 1 150 ? 19.040  -4.267  -13.137 1.000 61.097  0 150 ASP   B CG    1 ? 
ATOM   2466 O  OD1   . ASP   B 1 150 ? 20.202  -4.231  -12.649 1.000 62.011  0 150 ASP   B OD1   1 ? 
ATOM   2467 O  OD2   . ASP   B 1 150 ? 18.730  -4.872  -14.192 1.000 74.351  0 150 ASP   B OD2   1 ? 
ATOM   2468 N  N     . PHE   B 1 151 ? 20.148  -1.520  -11.774 1.000 54.292  0 151 PHE   B N     1 ? 
ATOM   2469 C  CA    . PHE   B 1 151 ? 20.856  -0.275  -12.001 1.000 52.932  0 151 PHE   B CA    1 ? 
ATOM   2470 C  C     . PHE   B 1 151 ? 20.685  0.171   -13.452 1.000 55.790  0 151 PHE   B C     1 ? 
ATOM   2471 O  O     . PHE   B 1 151 ? 20.668  -0.656  -14.357 1.000 60.187  0 151 PHE   B O     1 ? 
ATOM   2472 C  CB    . PHE   B 1 151 ? 22.352  -0.413  -11.725 1.000 52.675  0 151 PHE   B CB    1 ? 
ATOM   2473 C  CG    . PHE   B 1 151 ? 22.779  -0.737  -10.303 1.000 56.142  0 151 PHE   B CG    1 ? 
ATOM   2474 C  CD1   . PHE   B 1 151 ? 22.737  0.226   -9.301  1.000 60.403  0 151 PHE   B CD1   1 ? 
ATOM   2475 C  CD2   . PHE   B 1 151 ? 23.293  -1.990  -9.979  1.000 60.876  0 151 PHE   B CD2   1 ? 
ATOM   2476 C  CE1   . PHE   B 1 151 ? 23.151  -0.068  -8.008  1.000 60.307  0 151 PHE   B CE1   1 ? 
ATOM   2477 C  CE2   . PHE   B 1 151 ? 23.690  -2.283  -8.679  1.000 62.290  0 151 PHE   B CE2   1 ? 
ATOM   2478 C  CZ    . PHE   B 1 151 ? 23.627  -1.319  -7.700  1.000 62.846  0 151 PHE   B CZ    1 ? 
ATOM   2479 N  N     . TYR   B 1 152 ? 20.584  1.487   -13.663 1.000 57.534  0 152 TYR   B N     1 ? 
ATOM   2480 C  CA    . TYR   B 1 152 ? 20.709  2.102   -14.979 1.000 62.443  0 152 TYR   B CA    1 ? 
ATOM   2481 C  C     . TYR   B 1 152 ? 21.996  1.643   -15.658 1.000 61.986  0 152 TYR   B C     1 ? 
ATOM   2482 O  O     . TYR   B 1 152 ? 23.057  1.646   -15.044 1.000 61.723  0 152 TYR   B O     1 ? 
ATOM   2483 C  CB    . TYR   B 1 152 ? 20.728  3.623   -14.827 1.000 53.325  0 152 TYR   B CB    1 ? 
ATOM   2484 C  CG    . TYR   B 1 152 ? 20.730  4.492   -16.078 1.000 55.553  0 152 TYR   B CG    1 ? 
ATOM   2485 C  CD1   . TYR   B 1 152 ? 19.976  4.180   -17.204 1.000 58.897  0 152 TYR   B CD1   1 ? 
ATOM   2486 C  CD2   . TYR   B 1 152 ? 21.465  5.666   -16.113 1.000 58.483  0 152 TYR   B CD2   1 ? 
ATOM   2487 C  CE1   . TYR   B 1 152 ? 19.960  5.007   -18.320 1.000 54.594  0 152 TYR   B CE1   1 ? 
ATOM   2488 C  CE2   . TYR   B 1 152 ? 21.442  6.510   -17.208 1.000 57.759  0 152 TYR   B CE2   1 ? 
ATOM   2489 C  CZ    . TYR   B 1 152 ? 20.715  6.168   -18.329 1.000 56.376  0 152 TYR   B CZ    1 ? 
ATOM   2490 O  OH    . TYR   B 1 152 ? 20.765  7.041   -19.375 1.000 48.648  0 152 TYR   B OH    1 ? 
ATOM   2491 N  N     . GLU   B 1 153 ? 21.862  1.216   -16.918 1.000 67.432  0 153 GLU   B N     1 ? 
ATOM   2492 C  CA    . GLU   B 1 153 ? 22.992  0.872   -17.770 1.000 70.375  0 153 GLU   B CA    1 ? 
ATOM   2493 C  C     . GLU   B 1 153 ? 23.324  2.149   -18.540 1.000 68.293  0 153 GLU   B C     1 ? 
ATOM   2494 O  O     . GLU   B 1 153 ? 22.927  2.313   -19.693 1.000 80.186  0 153 GLU   B O     1 ? 
ATOM   2495 C  CB    . GLU   B 1 153 ? 22.675  -0.366  -18.626 1.000 57.392  0 153 GLU   B CB    1 ? 
ATOM   2496 N  N     . GLY   B 1 154 ? 23.988  3.081   -17.844 1.000 61.937  0 154 GLY   B N     1 ? 
ATOM   2497 C  CA    . GLY   B 1 154 ? 24.215  4.413   -18.365 1.000 53.215  0 154 GLY   B CA    1 ? 
ATOM   2498 C  C     . GLY   B 1 154 ? 24.968  5.279   -17.375 1.000 51.301  0 154 GLY   B C     1 ? 
ATOM   2499 O  O     . GLY   B 1 154 ? 25.305  4.838   -16.296 1.000 60.374  0 154 GLY   B O     1 ? 
ATOM   2500 N  N     . ALA   B 1 155 ? 25.219  6.526   -17.765 1.000 54.653  0 155 ALA   B N     1 ? 
ATOM   2501 C  CA    . ALA   B 1 155 ? 26.070  7.396   -16.979 1.000 66.750  0 155 ALA   B CA    1 ? 
ATOM   2502 C  C     . ALA   B 1 155 ? 25.252  8.151   -15.929 1.000 61.313  0 155 ALA   B C     1 ? 
ATOM   2503 O  O     . ALA   B 1 155 ? 24.033  8.323   -16.060 1.000 58.076  0 155 ALA   B O     1 ? 
ATOM   2504 C  CB    . ALA   B 1 155 ? 26.815  8.335   -17.901 1.000 59.349  0 155 ALA   B CB    1 ? 
ATOM   2505 N  N     . VAL   B 1 156 ? 25.952  8.610   -14.892 1.000 57.785  0 156 VAL   B N     1 ? 
ATOM   2506 C  CA    . VAL   B 1 156 ? 25.337  9.432   -13.860 1.000 70.446  0 156 VAL   B CA    1 ? 
ATOM   2507 C  C     . VAL   B 1 156 ? 26.336  10.495  -13.408 1.000 67.849  0 156 VAL   B C     1 ? 
ATOM   2508 O  O     . VAL   B 1 156 ? 27.467  10.149  -13.071 1.000 77.115  0 156 VAL   B O     1 ? 
ATOM   2509 C  CB    . VAL   B 1 156 ? 24.788  8.556   -12.712 1.000 70.618  0 156 VAL   B CB    1 ? 
ATOM   2510 C  CG1   . VAL   B 1 156 ? 25.255  7.105   -12.769 1.000 82.187  0 156 VAL   B CG1   1 ? 
ATOM   2511 C  CG2   . VAL   B 1 156 ? 25.078  9.141   -11.343 1.000 81.949  0 156 VAL   B CG2   1 ? 
ATOM   2512 N  N     . TYR   B 1 157 ? 25.890  11.770  -13.351 1.000 69.132  0 157 TYR   B N     1 ? 
ATOM   2513 C  CA    . TYR   B 1 157 ? 26.721  12.895  -12.913 1.000 67.539  0 157 TYR   B CA    1 ? 
ATOM   2514 C  C     . TYR   B 1 157 ? 26.323  13.380  -11.468 1.000 71.063  0 157 TYR   B C     1 ? 
ATOM   2515 O  O     . TYR   B 1 157 ? 27.237  13.913  -10.758 1.000 87.341  0 157 TYR   B O     1 ? 
ATOM   2516 C  CB    . TYR   B 1 157 ? 26.622  14.010  -13.965 1.000 60.942  0 157 TYR   B CB    1 ? 
ATOM   2517 C  CG    . TYR   B 1 157 ? 25.260  14.699  -13.959 1.000 61.877  0 157 TYR   B CG    1 ? 
ATOM   2518 C  CD1   . TYR   B 1 157 ? 24.982  15.742  -13.086 1.000 65.006  0 157 TYR   B CD1   1 ? 
ATOM   2519 C  CD2   . TYR   B 1 157 ? 24.245  14.319  -14.824 1.000 54.788  0 157 TYR   B CD2   1 ? 
ATOM   2520 C  CE1   . TYR   B 1 157 ? 23.748  16.384  -13.083 1.000 64.070  0 157 TYR   B CE1   1 ? 
ATOM   2521 C  CE2   . TYR   B 1 157 ? 23.000  14.939  -14.822 1.000 60.365  0 157 TYR   B CE2   1 ? 
ATOM   2522 C  CZ    . TYR   B 1 157 ? 22.744  15.978  -13.947 1.000 61.806  0 157 TYR   B CZ    1 ? 
ATOM   2523 O  OH    . TYR   B 1 157 ? 21.502  16.558  -13.912 1.000 49.618  0 157 TYR   B OH    1 ? 
ATOM   2524 O  OXT   . TYR   B 1 157 ? 25.124  13.241  -11.073 1.000 73.528  0 157 TYR   B OXT   1 ? 
HETATM 2525 N  N1    . DCZ   C 2 .   ? 24.111  15.554  -5.972  0.500 51.690  0 201 DCZ   A N1    1 ? 
HETATM 2526 C  C2    . DCZ   C 2 .   ? 25.355  15.102  -5.510  1.000 59.510  0 201 DCZ   A C2    1 ? 
HETATM 2527 N  N3    . DCZ   C 2 .   ? 26.315  14.691  -6.397  1.000 54.445  0 201 DCZ   A N3    1 ? 
HETATM 2528 C  C4    . DCZ   C 2 .   ? 26.099  14.640  -7.718  1.000 53.992  0 201 DCZ   A C4    1 ? 
HETATM 2529 C  C5    . DCZ   C 2 .   ? 24.824  15.036  -8.206  1.000 48.392  0 201 DCZ   A C5    1 ? 
HETATM 2530 C  C6    . DCZ   C 2 .   ? 23.894  15.473  -7.320  1.000 55.846  0 201 DCZ   A C6    1 ? 
HETATM 2531 O  O2    . DCZ   C 2 .   ? 25.592  15.142  -4.284  1.000 58.036  0 201 DCZ   A O2    1 ? 
HETATM 2532 N  N4    . DCZ   C 2 .   ? 27.106  14.226  -8.534  1.000 50.056  0 201 DCZ   A N4    1 ? 
HETATM 2533 C  "C1'" . DCZ   C 2 .   ? 23.063  16.096  -4.968  0.500 51.172  0 201 DCZ   A "C1'" 1 ? 
HETATM 2534 C  "C2'" . DCZ   C 2 .   ? 23.455  17.327  -4.110  1.000 52.200  0 201 DCZ   A "C2'" 1 ? 
HETATM 2535 C  "C3'" . DCZ   C 2 .   ? 22.735  18.571  -4.646  1.000 53.700  0 201 DCZ   A "C3'" 1 ? 
HETATM 2536 C  "C4'" . DCZ   C 2 .   ? 21.880  17.996  -5.772  1.000 51.317  0 201 DCZ   A "C4'" 1 ? 
HETATM 2537 O  "O4'" . DCZ   C 2 .   ? 21.885  16.554  -5.606  1.000 52.643  0 201 DCZ   A "O4'" 1 ? 
HETATM 2538 O  "O3'" . DCZ   C 2 .   ? 21.874  19.355  -3.795  1.000 51.614  0 201 DCZ   A "O3'" 1 ? 
HETATM 2539 C  "C5'" . DCZ   C 2 .   ? 22.460  18.430  -7.111  1.000 55.402  0 201 DCZ   A "C5'" 1 ? 
HETATM 2540 O  "O5'" . DCZ   C 2 .   ? 21.783  18.022  -8.295  1.000 52.233  0 201 DCZ   A "O5'" 1 ? 
HETATM 2541 C  C1    A A1H8P D 3 .   ? 1.101   21.602  -13.337 0.500 78.220  0 202 A1H8P A C1    1 ? 
HETATM 2542 C  C2    A A1H8P D 3 .   ? 0.233   20.585  -13.032 0.500 74.630  0 202 A1H8P A C2    1 ? 
HETATM 2543 C  C3    A A1H8P D 3 .   ? 0.697   19.460  -12.343 0.500 71.590  0 202 A1H8P A C3    1 ? 
HETATM 2544 N  N1    A A1H8P D 3 .   ? 1.966   19.270  -11.955 0.500 69.360  0 202 A1H8P A N1    1 ? 
HETATM 2545 C  C4    A A1H8P D 3 .   ? 2.777   20.270  -12.270 0.500 61.540  0 202 A1H8P A C4    1 ? 
HETATM 2546 C  C5    A A1H8P D 3 .   ? 4.505   21.569  -12.548 0.500 69.874  0 202 A1H8P A C5    1 ? 
HETATM 2547 C  C6    A A1H8P D 3 .   ? 2.422   21.433  -12.940 0.500 66.472  0 202 A1H8P A C6    1 ? 
HETATM 2548 BR BR1   A A1H8P D 3 .   ? 0.579   23.155  -14.297 0.500 103.828 0 202 A1H8P A BR1   1 ? 
HETATM 2549 N  N2    A A1H8P D 3 .   ? 4.106   20.377  -12.031 0.500 63.594  0 202 A1H8P A N2    1 ? 
HETATM 2550 N  N3    A A1H8P D 3 .   ? 3.538   22.243  -13.110 0.500 79.684  0 202 A1H8P A N3    1 ? 
HETATM 2551 C  C2    . 2DR   E 4 .   ? 3.512   16.250  -12.493 1.000 83.483  0 201 2DR   B C2    1 ? 
HETATM 2552 C  C3    . 2DR   E 4 .   ? 4.634   16.131  -13.533 1.000 86.667  0 201 2DR   B C3    1 ? 
HETATM 2553 C  C4    . 2DR   E 4 .   ? 5.747   17.058  -13.003 1.000 83.140  0 201 2DR   B C4    1 ? 
HETATM 2554 C  C5    . 2DR   E 4 .   ? 6.022   18.265  -13.882 1.000 81.768  0 201 2DR   B C5    1 ? 
HETATM 2555 O  O3    . 2DR   E 4 .   ? 5.038   14.770  -13.594 1.000 64.378  0 201 2DR   B O3    1 ? 
HETATM 2556 O  O4    . 2DR   E 4 .   ? 5.305   17.476  -11.692 1.000 80.500  0 201 2DR   B O4    1 ? 
HETATM 2557 O  O5    . 2DR   E 4 .   ? 7.095   19.127  -13.500 1.000 68.266  0 201 2DR   B O5    1 ? 
HETATM 2558 C  C1    . 2DR   E 4 .   ? 4.267   16.599  -11.224 0.500 82.054  0 201 2DR   B C1    1 ? 
HETATM 2559 C  C1    B A1H8P F 3 .   ? -2.397  20.200  -13.803 0.500 80.761  0 202 A1H8P B C1    1 ? 
HETATM 2560 C  C2    B A1H8P F 3 .   ? -2.820  18.987  -13.325 0.500 80.900  0 202 A1H8P B C2    1 ? 
HETATM 2561 C  C3    B A1H8P F 3 .   ? -1.951  18.242  -12.537 0.500 81.683  0 202 A1H8P B C3    1 ? 
HETATM 2562 N  N1    B A1H8P F 3 .   ? -0.702  18.640  -12.211 0.500 82.504  0 202 A1H8P B N1    1 ? 
HETATM 2563 C  C4    B A1H8P F 3 .   ? -0.330  19.833  -12.684 0.500 79.533  0 202 A1H8P B C4    1 ? 
HETATM 2564 C  C5    B A1H8P F 3 .   ? 0.697   21.691  -13.210 0.500 77.632  0 202 A1H8P B C5    1 ? 
HETATM 2565 C  C6    B A1H8P F 3 .   ? -1.128  20.637  -13.473 0.500 73.594  0 202 A1H8P B C6    1 ? 
HETATM 2566 BR BR1   B A1H8P F 3 .   ? -3.428  21.334  -14.861 0.600 103.522 0 202 A1H8P B BR1   1 ? 
HETATM 2567 N  N2    B A1H8P F 3 .   ? 0.844   20.524  -12.526 0.500 74.949  0 202 A1H8P B N2    1 ? 
HETATM 2568 N  N3    B A1H8P F 3 .   ? -0.466  21.808  -13.807 0.500 77.734  0 202 A1H8P B N3    1 ? 
HETATM 2569 O  O     . HOH   G 5 .   ? 40.299  8.312   -6.887  1.000 58.601  0 301 HOH   A O     1 ? 
HETATM 2570 O  O     . HOH   G 5 .   ? 32.513  18.710  14.588  1.000 51.534  0 302 HOH   A O     1 ? 
HETATM 2571 O  O     . HOH   G 5 .   ? 15.792  25.614  19.073  1.000 55.737  0 303 HOH   A O     1 ? 
HETATM 2572 O  O     . HOH   G 5 .   ? 23.760  30.274  -15.524 1.000 57.647  0 304 HOH   A O     1 ? 
HETATM 2573 O  O     . HOH   G 5 .   ? 31.399  24.027  -0.988  1.000 52.808  0 305 HOH   A O     1 ? 
HETATM 2574 O  O     . HOH   G 5 .   ? 24.777  21.222  -3.009  1.000 48.031  0 306 HOH   A O     1 ? 
HETATM 2575 O  O     . HOH   G 5 .   ? 29.704  19.479  5.291   1.000 47.692  0 307 HOH   A O     1 ? 
HETATM 2576 O  O     . HOH   G 5 .   ? 10.010  31.307  9.649   1.000 50.618  0 308 HOH   A O     1 ? 
HETATM 2577 O  O     . HOH   G 5 .   ? 16.752  5.731   -1.400  1.000 59.016  0 309 HOH   A O     1 ? 
HETATM 2578 O  O     . HOH   G 5 .   ? 22.976  26.577  -6.651  1.000 49.886  0 310 HOH   A O     1 ? 
HETATM 2579 O  O     . HOH   G 5 .   ? 32.419  20.812  -9.181  1.000 55.356  0 311 HOH   A O     1 ? 
HETATM 2580 O  O     . HOH   G 5 .   ? 22.439  33.269  -9.341  1.000 58.073  0 312 HOH   A O     1 ? 
HETATM 2581 O  O     . HOH   G 5 .   ? 20.674  25.459  -7.441  1.000 58.332  0 313 HOH   A O     1 ? 
HETATM 2582 O  O     . HOH   G 5 .   ? 25.112  36.434  0.591   1.000 63.465  0 314 HOH   A O     1 ? 
HETATM 2583 O  O     . HOH   G 5 .   ? 29.548  17.066  -10.540 1.000 57.735  0 315 HOH   A O     1 ? 
HETATM 2584 O  O     . HOH   G 5 .   ? 4.207   40.963  -3.953  1.000 58.992  0 316 HOH   A O     1 ? 
HETATM 2585 O  O     . HOH   G 5 .   ? 18.011  19.210  -13.463 1.000 56.436  0 317 HOH   A O     1 ? 
HETATM 2586 O  O     . HOH   G 5 .   ? 20.753  21.973  -12.791 1.000 55.740  0 318 HOH   A O     1 ? 
HETATM 2587 O  O     . HOH   G 5 .   ? 21.857  37.025  3.412   1.000 52.498  0 319 HOH   A O     1 ? 
HETATM 2588 O  O     . HOH   G 5 .   ? 22.940  35.343  -7.579  1.000 55.901  0 320 HOH   A O     1 ? 
HETATM 2589 O  O     . HOH   G 5 .   ? 21.136  37.306  -4.703  1.000 60.102  0 321 HOH   A O     1 ? 
HETATM 2590 O  O     . HOH   G 5 .   ? 18.242  25.530  -8.995  1.000 48.442  0 322 HOH   A O     1 ? 
HETATM 2591 O  O     . HOH   G 5 .   ? 27.389  21.178  -2.013  1.000 44.248  0 323 HOH   A O     1 ? 
HETATM 2592 O  O     . HOH   G 5 .   ? 16.202  23.852  -8.256  1.000 51.528  0 324 HOH   A O     1 ? 
HETATM 2593 O  O     . HOH   G 5 .   ? 16.085  6.585   4.688   1.000 53.893  0 325 HOH   A O     1 ? 
HETATM 2594 O  O     . HOH   G 5 .   ? 18.862  35.725  13.151  1.000 61.438  0 326 HOH   A O     1 ? 
HETATM 2595 O  O     . HOH   G 5 .   ? 26.266  28.534  -17.496 1.000 58.205  0 327 HOH   A O     1 ? 
HETATM 2596 O  O     . HOH   G 5 .   ? 29.444  16.088  7.532   1.000 52.504  0 328 HOH   A O     1 ? 
HETATM 2597 O  O     . HOH   G 5 .   ? 24.462  37.447  2.967   1.000 56.120  0 329 HOH   A O     1 ? 
HETATM 2598 O  O     . HOH   G 5 .   ? 31.291  25.408  4.161   1.000 59.547  0 330 HOH   A O     1 ? 
HETATM 2599 O  O     . HOH   H 5 .   ? -6.567  4.275   -8.787  1.000 63.616  0 301 HOH   B O     1 ? 
HETATM 2600 O  O     . HOH   H 5 .   ? -5.782  12.987  -6.763  1.000 60.572  0 302 HOH   B O     1 ? 
HETATM 2601 O  O     . HOH   H 5 .   ? 4.784   -0.349  -5.522  1.000 55.777  0 303 HOH   B O     1 ? 
HETATM 2602 O  O     . HOH   H 5 .   ? 24.253  2.332   -12.855 1.000 55.392  0 304 HOH   B O     1 ? 
HETATM 2603 O  O     . HOH   H 5 .   ? 1.677   36.503  -6.867  1.000 67.142  0 305 HOH   B O     1 ? 
HETATM 2604 O  O     . HOH   H 5 .   ? 3.634   18.340  0.905   1.000 50.658  0 306 HOH   B O     1 ? 
HETATM 2605 O  O     . HOH   H 5 .   ? 12.836  14.769  -18.062 1.000 52.256  0 307 HOH   B O     1 ? 
HETATM 2606 O  O     . HOH   H 5 .   ? 11.316  12.108  -26.467 1.000 58.597  0 308 HOH   B O     1 ? 
HETATM 2607 O  O     . HOH   H 5 .   ? 22.096  15.022  -18.990 1.000 66.102  0 309 HOH   B O     1 ? 
HETATM 2608 O  O     . HOH   H 5 .   ? 18.188  2.042   -9.900  1.000 54.700  0 310 HOH   B O     1 ? 
HETATM 2609 O  O     . HOH   H 5 .   ? 11.725  6.017   -27.591 1.000 60.709  0 311 HOH   B O     1 ? 
HETATM 2610 O  O     . HOH   H 5 .   ? 18.695  18.182  -17.990 1.000 58.721  0 312 HOH   B O     1 ? 
HETATM 2611 O  O     . HOH   H 5 .   ? 8.692   13.803  -19.330 1.000 62.684  0 313 HOH   B O     1 ? 
HETATM 2612 O  O     . HOH   H 5 .   ? 1.047   15.873  -24.407 1.000 65.936  0 314 HOH   B O     1 ? 
HETATM 2613 O  O     . HOH   H 5 .   ? -6.233  6.899   -9.428  1.000 65.380  0 315 HOH   B O     1 ? 
HETATM 2614 O  O     . HOH   H 5 .   ? 22.058  7.216   -26.029 1.000 66.076  0 316 HOH   B O     1 ? 
HETATM 2615 O  O     . HOH   H 5 .   ? 19.836  3.105   -11.136 1.000 53.432  0 317 HOH   B O     1 ? 
HETATM 2616 O  O     . HOH   H 5 .   ? 2.543   -11.343 -13.852 1.000 58.503  0 318 HOH   B O     1 ? 
HETATM 2617 O  O     . HOH   H 5 .   ? 19.097  -1.957  -16.766 1.000 62.974  0 319 HOH   B O     1 ? 
HETATM 2618 O  O     . HOH   H 5 .   ? -12.668 -0.069  -13.935 1.000 55.392  0 320 HOH   B O     1 ? 
HETATM 2619 O  O     . HOH   H 5 .   ? -1.999  14.021  0.114   1.000 55.423  0 321 HOH   B O     1 ? 
HETATM 2620 O  O     . HOH   H 5 .   ? 10.700  22.366  -27.348 1.000 61.373  0 322 HOH   B O     1 ? 
HETATM 2621 O  O     . HOH   H 5 .   ? -9.651  27.230  -7.875  1.000 72.572  0 323 HOH   B O     1 ? 
HETATM 2622 O  O     . HOH   H 5 .   ? 18.208  -8.709  -15.878 1.000 68.361  0 324 HOH   B O     1 ? 
HETATM 2623 O  O     . HOH   H 5 .   ? 11.933  -5.452  -17.996 1.000 62.988  0 325 HOH   B O     1 ? 
HETATM 2624 O  O     . HOH   H 5 .   ? 25.238  18.825  -15.851 1.000 69.367  0 326 HOH   B O     1 ? 
# 
