data_9F08
# 
_entry.id   9F08 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9F08         pdb_00009f08 10.2210/pdb9f08/pdb 
WWPDB D_1292137912 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_database_PDB_caveat.id 
_database_PDB_caveat.text 
1 '2DR A 201 HAS WRONG CHIRALITY AT ATOM C1' 
2 '2DR B 201 HAS WRONG CHIRALITY AT ATOM C1' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9F08 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gideon.grogan@york.ac.uk 
_pdbx_contact_author.name_first         Gideon 
_pdbx_contact_author.name_last          Grogan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1383-7056 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ascham, A.'    1 ?                   
'Salihovic, A.' 2 ?                   
'Burley, G.'    3 0000-0002-4896-113X 
'Grogan, G.'    4 0000-0003-1383-7056 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Chem Sci' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-6520 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                15399 
_citation.page_last                 15407 
_citation.title                     
;Gram-scale enzymatic synthesis of 2'-deoxyribonucleoside analogues using nucleoside transglycosylase-2.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1039/d4sc04938a 
_citation.pdbx_database_id_PubMed   39234214 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Salihovic, A.'       1 0009-0004-4710-0145 
primary 'Ascham, A.'          2 0000-0002-1930-4667 
primary 'Taladriz-Sender, A.' 3 0000-0002-8274-4761 
primary 'Bryson, S.'          4 ?                   
primary 'Withers, J.M.'       5 ?                   
primary 'McKean, I.J.W.'      6 ?                   
primary 'Hoskisson, P.A.'     7 0000-0003-4332-1640 
primary 'Grogan, G.'          8 0000-0003-1383-7056 
primary 'Burley, G.A.'        9 0000-0002-4896-113X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Nucleoside deoxyribosyltransferase' 18098.354 2  ? ? ? ? 
2 non-polymer syn 2-deoxy-beta-D-erythro-pentofuranose 134.130   2  ? ? ? ? 
3 water       nat water                                18.015    36 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTND
IMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTND
IMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 2-deoxy-beta-D-erythro-pentofuranose 2DR 
3 water                                HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   LYS n 
1 4   LYS n 
1 5   THR n 
1 6   ILE n 
1 7   TYR n 
1 8   PHE n 
1 9   GLY n 
1 10  ALA n 
1 11  GLY n 
1 12  TRP n 
1 13  PHE n 
1 14  THR n 
1 15  ASP n 
1 16  ARG n 
1 17  GLN n 
1 18  ASN n 
1 19  LYS n 
1 20  ALA n 
1 21  TYR n 
1 22  LYS n 
1 23  GLU n 
1 24  ALA n 
1 25  MET n 
1 26  GLU n 
1 27  ALA n 
1 28  LEU n 
1 29  LYS n 
1 30  GLU n 
1 31  ASN n 
1 32  PRO n 
1 33  THR n 
1 34  ILE n 
1 35  ASP n 
1 36  LEU n 
1 37  GLU n 
1 38  ASN n 
1 39  SER n 
1 40  TYR n 
1 41  VAL n 
1 42  PRO n 
1 43  LEU n 
1 44  ASP n 
1 45  ASN n 
1 46  GLN n 
1 47  TYR n 
1 48  LYS n 
1 49  GLY n 
1 50  ILE n 
1 51  ARG n 
1 52  VAL n 
1 53  ASP n 
1 54  GLU n 
1 55  HIS n 
1 56  PRO n 
1 57  GLU n 
1 58  TYR n 
1 59  LEU n 
1 60  HIS n 
1 61  ASP n 
1 62  LYS n 
1 63  VAL n 
1 64  TRP n 
1 65  ALA n 
1 66  THR n 
1 67  ALA n 
1 68  THR n 
1 69  TYR n 
1 70  ASN n 
1 71  ASN n 
1 72  ASP n 
1 73  LEU n 
1 74  ASN n 
1 75  GLY n 
1 76  ILE n 
1 77  LYS n 
1 78  THR n 
1 79  ASN n 
1 80  ASP n 
1 81  ILE n 
1 82  MET n 
1 83  LEU n 
1 84  GLY n 
1 85  VAL n 
1 86  TYR n 
1 87  ILE n 
1 88  PRO n 
1 89  ASP n 
1 90  GLU n 
1 91  GLU n 
1 92  ASP n 
1 93  VAL n 
1 94  GLY n 
1 95  LEU n 
1 96  GLY n 
1 97  MET n 
1 98  GLU n 
1 99  LEU n 
1 100 GLY n 
1 101 TYR n 
1 102 ALA n 
1 103 LEU n 
1 104 SER n 
1 105 GLN n 
1 106 GLY n 
1 107 LYS n 
1 108 TYR n 
1 109 VAL n 
1 110 LEU n 
1 111 LEU n 
1 112 VAL n 
1 113 ILE n 
1 114 PRO n 
1 115 ASP n 
1 116 GLU n 
1 117 ASP n 
1 118 TYR n 
1 119 GLY n 
1 120 LYS n 
1 121 PRO n 
1 122 ILE n 
1 123 ASN n 
1 124 LEU n 
1 125 MET n 
1 126 SER n 
1 127 TRP n 
1 128 GLY n 
1 129 VAL n 
1 130 SER n 
1 131 ASP n 
1 132 ASN n 
1 133 VAL n 
1 134 ILE n 
1 135 LYS n 
1 136 MET n 
1 137 SER n 
1 138 GLN n 
1 139 LEU n 
1 140 LYS n 
1 141 ASP n 
1 142 PHE n 
1 143 ASN n 
1 144 PHE n 
1 145 ASN n 
1 146 LYS n 
1 147 PRO n 
1 148 ARG n 
1 149 PHE n 
1 150 ASP n 
1 151 PHE n 
1 152 TYR n 
1 153 GLU n 
1 154 GLY n 
1 155 ALA n 
1 156 VAL n 
1 157 TYR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   157 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ntd 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Lactobacillus leichmannii' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     28039 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
2DR 'D-saccharide, beta linking' . 2-deoxy-beta-D-erythro-pentofuranose 
'2-deoxy-beta-D-ribofuranose; 2-deoxy-beta-D-erythro-pentose; 2-deoxy-D-erythro-pentose; 2-deoxy-erythro-pentose' 'C5 H10 O4'      
134.130 
ALA 'L-peptide linking'          y ALANINE                              ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                             ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                           ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'     133.103 
GLN 'L-peptide linking'          y GLUTAMINE                            ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                              ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                            ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                  . WATER                                ? 'H2 O'           18.015  
ILE 'L-peptide linking'          y ISOLEUCINE                           ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                              ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                               ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                           ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking'          y PHENYLALANINE                        ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                              ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                               ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                            ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                           ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                             ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                               ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   PRO 2   2   2   PRO PRO A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   LYS 4   4   4   LYS LYS A . n 
A 1 5   THR 5   5   5   THR THR A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   TYR 7   7   7   TYR TYR A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   GLY 9   9   9   GLY GLY A . n 
A 1 10  ALA 10  10  10  ALA ALA A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  TRP 12  12  12  TRP TRP A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  THR 14  14  14  THR THR A . n 
A 1 15  ASP 15  15  15  ASP ASP A . n 
A 1 16  ARG 16  16  16  ARG ARG A . n 
A 1 17  GLN 17  17  17  GLN GLN A . n 
A 1 18  ASN 18  18  18  ASN ASN A . n 
A 1 19  LYS 19  19  19  LYS LYS A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  TYR 21  21  21  TYR TYR A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  GLU 23  23  23  GLU GLU A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  MET 25  25  25  MET MET A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  LEU 28  28  28  LEU LEU A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  ILE 34  34  34  ILE ILE A . n 
A 1 35  ASP 35  35  35  ASP ASP A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  GLU 37  37  37  GLU GLU A . n 
A 1 38  ASN 38  38  38  ASN ASN A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  TYR 40  40  40  TYR TYR A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  ASP 44  44  44  ASP ASP A . n 
A 1 45  ASN 45  45  45  ASN ASN A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  TYR 47  47  47  TYR TYR A . n 
A 1 48  LYS 48  48  48  LYS LYS A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  ILE 50  50  50  ILE ILE A . n 
A 1 51  ARG 51  51  51  ARG ARG A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  ASP 53  53  53  ASP ASP A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  HIS 55  55  55  HIS HIS A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  GLU 57  57  57  GLU GLU A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  TRP 64  64  64  TRP TRP A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  ASN 70  70  70  ASN ASN A . n 
A 1 71  ASN 71  71  71  ASN ASN A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  GLY 75  75  75  GLY GLY A . n 
A 1 76  ILE 76  76  76  ILE ILE A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  ASP 80  80  80  ASP ASP A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  MET 82  82  82  MET MET A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  TYR 86  86  86  TYR TYR A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  PRO 88  88  88  PRO PRO A . n 
A 1 89  ASP 89  89  89  ASP ASP A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  ASP 92  92  92  ASP ASP A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  MET 97  97  97  MET MET A . n 
A 1 98  GLU 98  98  98  GLU GLU A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 SER 104 104 104 SER SER A . n 
A 1 105 GLN 105 105 105 GLN GLN A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 LYS 107 107 107 LYS LYS A . n 
A 1 108 TYR 108 108 108 TYR TYR A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 VAL 112 112 112 VAL VAL A . n 
A 1 113 ILE 113 113 113 ILE ILE A . n 
A 1 114 PRO 114 114 114 PRO PRO A . n 
A 1 115 ASP 115 115 115 ASP ASP A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 LYS 120 120 120 LYS LYS A . n 
A 1 121 PRO 121 121 121 PRO PRO A . n 
A 1 122 ILE 122 122 122 ILE ILE A . n 
A 1 123 ASN 123 123 123 ASN ASN A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 MET 125 125 125 MET MET A . n 
A 1 126 SER 126 126 126 SER SER A . n 
A 1 127 TRP 127 127 127 TRP TRP A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 VAL 129 129 129 VAL VAL A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 ASP 131 131 131 ASP ASP A . n 
A 1 132 ASN 132 132 132 ASN ASN A . n 
A 1 133 VAL 133 133 133 VAL VAL A . n 
A 1 134 ILE 134 134 134 ILE ILE A . n 
A 1 135 LYS 135 135 135 LYS LYS A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 ASP 141 141 141 ASP ASP A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 PHE 144 144 144 PHE PHE A . n 
A 1 145 ASN 145 145 145 ASN ASN A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 PRO 147 147 147 PRO PRO A . n 
A 1 148 ARG 148 148 148 ARG ARG A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 PHE 151 151 151 PHE PHE A . n 
A 1 152 TYR 152 152 152 TYR TYR A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 ALA 155 155 155 ALA ALA A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 TYR 157 157 157 TYR TYR A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   PRO 2   2   2   PRO PRO B . n 
B 1 3   LYS 3   3   3   LYS LYS B . n 
B 1 4   LYS 4   4   4   LYS LYS B . n 
B 1 5   THR 5   5   5   THR THR B . n 
B 1 6   ILE 6   6   6   ILE ILE B . n 
B 1 7   TYR 7   7   7   TYR TYR B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   GLY 9   9   9   GLY GLY B . n 
B 1 10  ALA 10  10  10  ALA ALA B . n 
B 1 11  GLY 11  11  11  GLY GLY B . n 
B 1 12  TRP 12  12  12  TRP TRP B . n 
B 1 13  PHE 13  13  13  PHE PHE B . n 
B 1 14  THR 14  14  14  THR THR B . n 
B 1 15  ASP 15  15  15  ASP ASP B . n 
B 1 16  ARG 16  16  16  ARG ARG B . n 
B 1 17  GLN 17  17  17  GLN GLN B . n 
B 1 18  ASN 18  18  18  ASN ASN B . n 
B 1 19  LYS 19  19  19  LYS LYS B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  TYR 21  21  21  TYR TYR B . n 
B 1 22  LYS 22  22  22  LYS LYS B . n 
B 1 23  GLU 23  23  23  GLU GLU B . n 
B 1 24  ALA 24  24  24  ALA ALA B . n 
B 1 25  MET 25  25  25  MET MET B . n 
B 1 26  GLU 26  26  26  GLU GLU B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  LEU 28  28  28  LEU LEU B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  ASN 31  31  31  ASN ASN B . n 
B 1 32  PRO 32  32  32  PRO PRO B . n 
B 1 33  THR 33  33  33  THR THR B . n 
B 1 34  ILE 34  34  34  ILE ILE B . n 
B 1 35  ASP 35  35  35  ASP ASP B . n 
B 1 36  LEU 36  36  36  LEU LEU B . n 
B 1 37  GLU 37  37  37  GLU GLU B . n 
B 1 38  ASN 38  38  38  ASN ASN B . n 
B 1 39  SER 39  39  39  SER SER B . n 
B 1 40  TYR 40  40  40  TYR TYR B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  LEU 43  43  43  LEU LEU B . n 
B 1 44  ASP 44  44  44  ASP ASP B . n 
B 1 45  ASN 45  45  45  ASN ASN B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  TYR 47  47  47  TYR TYR B . n 
B 1 48  LYS 48  48  48  LYS LYS B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  ILE 50  50  50  ILE ILE B . n 
B 1 51  ARG 51  51  51  ARG ARG B . n 
B 1 52  VAL 52  52  52  VAL VAL B . n 
B 1 53  ASP 53  53  53  ASP ASP B . n 
B 1 54  GLU 54  54  54  GLU GLU B . n 
B 1 55  HIS 55  55  55  HIS HIS B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  GLU 57  57  57  GLU GLU B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  LEU 59  59  59  LEU LEU B . n 
B 1 60  HIS 60  60  60  HIS HIS B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  LYS 62  62  62  LYS LYS B . n 
B 1 63  VAL 63  63  63  VAL VAL B . n 
B 1 64  TRP 64  64  64  TRP TRP B . n 
B 1 65  ALA 65  65  65  ALA ALA B . n 
B 1 66  THR 66  66  66  THR THR B . n 
B 1 67  ALA 67  67  67  ALA ALA B . n 
B 1 68  THR 68  68  68  THR THR B . n 
B 1 69  TYR 69  69  69  TYR TYR B . n 
B 1 70  ASN 70  70  70  ASN ASN B . n 
B 1 71  ASN 71  71  71  ASN ASN B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  GLY 75  75  75  GLY GLY B . n 
B 1 76  ILE 76  76  76  ILE ILE B . n 
B 1 77  LYS 77  77  77  LYS LYS B . n 
B 1 78  THR 78  78  78  THR THR B . n 
B 1 79  ASN 79  79  79  ASN ASN B . n 
B 1 80  ASP 80  80  80  ASP ASP B . n 
B 1 81  ILE 81  81  81  ILE ILE B . n 
B 1 82  MET 82  82  82  MET MET B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  GLY 84  84  84  GLY GLY B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  TYR 86  86  86  TYR TYR B . n 
B 1 87  ILE 87  87  87  ILE ILE B . n 
B 1 88  PRO 88  88  88  PRO PRO B . n 
B 1 89  ASP 89  89  89  ASP ASP B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  ASP 92  92  92  ASP ASP B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  GLY 96  96  96  GLY GLY B . n 
B 1 97  MET 97  97  97  MET MET B . n 
B 1 98  GLU 98  98  98  GLU GLU B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 ALA 102 102 102 ALA ALA B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 SER 104 104 104 SER SER B . n 
B 1 105 GLN 105 105 105 GLN GLN B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 LYS 107 107 107 LYS LYS B . n 
B 1 108 TYR 108 108 108 TYR TYR B . n 
B 1 109 VAL 109 109 109 VAL VAL B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 LEU 111 111 111 LEU LEU B . n 
B 1 112 VAL 112 112 112 VAL VAL B . n 
B 1 113 ILE 113 113 113 ILE ILE B . n 
B 1 114 PRO 114 114 114 PRO PRO B . n 
B 1 115 ASP 115 115 115 ASP ASP B . n 
B 1 116 GLU 116 116 116 GLU GLU B . n 
B 1 117 ASP 117 117 117 ASP ASP B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 GLY 119 119 119 GLY GLY B . n 
B 1 120 LYS 120 120 120 LYS LYS B . n 
B 1 121 PRO 121 121 121 PRO PRO B . n 
B 1 122 ILE 122 122 122 ILE ILE B . n 
B 1 123 ASN 123 123 123 ASN ASN B . n 
B 1 124 LEU 124 124 124 LEU LEU B . n 
B 1 125 MET 125 125 125 MET MET B . n 
B 1 126 SER 126 126 126 SER SER B . n 
B 1 127 TRP 127 127 127 TRP TRP B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 VAL 129 129 129 VAL VAL B . n 
B 1 130 SER 130 130 130 SER SER B . n 
B 1 131 ASP 131 131 131 ASP ASP B . n 
B 1 132 ASN 132 132 132 ASN ASN B . n 
B 1 133 VAL 133 133 133 VAL VAL B . n 
B 1 134 ILE 134 134 134 ILE ILE B . n 
B 1 135 LYS 135 135 135 LYS LYS B . n 
B 1 136 MET 136 136 136 MET MET B . n 
B 1 137 SER 137 137 137 SER SER B . n 
B 1 138 GLN 138 138 138 GLN GLN B . n 
B 1 139 LEU 139 139 139 LEU LEU B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 ASP 141 141 141 ASP ASP B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 PHE 144 144 144 PHE PHE B . n 
B 1 145 ASN 145 145 145 ASN ASN B . n 
B 1 146 LYS 146 146 146 LYS LYS B . n 
B 1 147 PRO 147 147 147 PRO PRO B . n 
B 1 148 ARG 148 148 148 ARG ARG B . n 
B 1 149 PHE 149 149 149 PHE PHE B . n 
B 1 150 ASP 150 150 150 ASP ASP B . n 
B 1 151 PHE 151 151 151 PHE PHE B . n 
B 1 152 TYR 152 152 152 TYR TYR B . n 
B 1 153 GLU 153 153 153 GLU GLU B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 ALA 155 155 155 ALA ALA B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 TYR 157 157 157 TYR TYR B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        2DR 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   2DR 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 2DR 1  201 201 2DR UNL A . 
D 2 2DR 1  201 201 2DR UNL B . 
E 3 HOH 1  301 38  HOH HOH A . 
E 3 HOH 2  302 32  HOH HOH A . 
E 3 HOH 3  303 5   HOH HOH A . 
E 3 HOH 4  304 9   HOH HOH A . 
E 3 HOH 5  305 17  HOH HOH A . 
E 3 HOH 6  306 13  HOH HOH A . 
E 3 HOH 7  307 37  HOH HOH A . 
E 3 HOH 8  308 2   HOH HOH A . 
E 3 HOH 9  309 12  HOH HOH A . 
E 3 HOH 10 310 28  HOH HOH A . 
E 3 HOH 11 311 8   HOH HOH A . 
E 3 HOH 12 312 3   HOH HOH A . 
E 3 HOH 13 313 15  HOH HOH A . 
E 3 HOH 14 314 6   HOH HOH A . 
E 3 HOH 15 315 11  HOH HOH A . 
E 3 HOH 16 316 16  HOH HOH A . 
E 3 HOH 17 317 23  HOH HOH A . 
E 3 HOH 18 318 33  HOH HOH A . 
E 3 HOH 19 319 19  HOH HOH A . 
E 3 HOH 20 320 34  HOH HOH A . 
F 3 HOH 1  301 20  HOH HOH B . 
F 3 HOH 2  302 29  HOH HOH B . 
F 3 HOH 3  303 7   HOH HOH B . 
F 3 HOH 4  304 36  HOH HOH B . 
F 3 HOH 5  305 27  HOH HOH B . 
F 3 HOH 6  306 31  HOH HOH B . 
F 3 HOH 7  307 26  HOH HOH B . 
F 3 HOH 8  308 4   HOH HOH B . 
F 3 HOH 9  309 10  HOH HOH B . 
F 3 HOH 10 310 14  HOH HOH B . 
F 3 HOH 11 311 18  HOH HOH B . 
F 3 HOH 12 312 35  HOH HOH B . 
F 3 HOH 13 313 25  HOH HOH B . 
F 3 HOH 14 314 22  HOH HOH B . 
F 3 HOH 15 315 21  HOH HOH B . 
F 3 HOH 16 316 24  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ILE 50  ? CG1 ? A ILE 50  CG1 
2  1 Y 1 A ILE 50  ? CG2 ? A ILE 50  CG2 
3  1 Y 1 A ILE 50  ? CD1 ? A ILE 50  CD1 
4  1 Y 1 B MET 1   ? CG  ? B MET 1   CG  
5  1 Y 1 B MET 1   ? SD  ? B MET 1   SD  
6  1 Y 1 B MET 1   ? CE  ? B MET 1   CE  
7  1 Y 1 B LYS 22  ? CG  ? B LYS 22  CG  
8  1 Y 1 B LYS 22  ? CD  ? B LYS 22  CD  
9  1 Y 1 B LYS 22  ? CE  ? B LYS 22  CE  
10 1 Y 1 B LYS 22  ? NZ  ? B LYS 22  NZ  
11 1 Y 1 B GLU 30  ? CD  ? B GLU 30  CD  
12 1 Y 1 B GLU 30  ? OE1 ? B GLU 30  OE1 
13 1 Y 1 B GLU 30  ? OE2 ? B GLU 30  OE2 
14 1 Y 1 B LYS 48  ? CE  ? B LYS 48  CE  
15 1 Y 1 B LYS 48  ? NZ  ? B LYS 48  NZ  
16 1 Y 1 B ARG 51  ? CG  ? B ARG 51  CG  
17 1 Y 1 B ARG 51  ? CD  ? B ARG 51  CD  
18 1 Y 1 B ARG 51  ? NE  ? B ARG 51  NE  
19 1 Y 1 B ARG 51  ? CZ  ? B ARG 51  CZ  
20 1 Y 1 B ARG 51  ? NH1 ? B ARG 51  NH1 
21 1 Y 1 B ARG 51  ? NH2 ? B ARG 51  NH2 
22 1 Y 1 B LYS 140 ? CG  ? B LYS 140 CG  
23 1 Y 1 B LYS 140 ? CD  ? B LYS 140 CD  
24 1 Y 1 B LYS 140 ? CE  ? B LYS 140 CE  
25 1 Y 1 B LYS 140 ? NZ  ? B LYS 140 NZ  
26 1 Y 1 B GLU 153 ? CG  ? B GLU 153 CG  
27 1 Y 1 B GLU 153 ? CD  ? B GLU 153 CD  
28 1 Y 1 B GLU 153 ? OE1 ? B GLU 153 OE1 
29 1 Y 1 B GLU 153 ? OE2 ? B GLU 153 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALA  ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9F08 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     148.461 
_cell.length_a_esd                 ? 
_cell.length_b                     148.461 
_cell.length_b_esd                 ? 
_cell.length_c                     148.461 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        48 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9F08 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                199 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 21 3' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9F08 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.77 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          67.35 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '35% tascimate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     120 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-01-20 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976277 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976277 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9F08 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.37 
_reflns.d_resolution_low                               60.61 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     22224 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                41.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          42.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.01 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.00 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.06 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.37 
_reflns_shell.d_res_low                                     2.46 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           5.1 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2312 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.22 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.95 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.96 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.000 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.000 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.000 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               63.329 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.959 
_refine.correlation_coeff_Fo_to_Fc_free          0.944 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9F08 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.371 
_refine.ls_d_res_low                             60.61 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     22212 
_refine.ls_number_reflns_R_free                  1115 
_refine.ls_number_reflns_R_work                  21097 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.982 
_refine.ls_percent_reflns_R_free                 5.020 
_refine.ls_R_factor_all                          0.201 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2284 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1990 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.234 
_refine.pdbx_overall_ESU_R_Free                  0.192 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             6.410 
_refine.overall_SU_ML                            0.150 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        2523 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         16 
_refine_hist.number_atoms_solvent             37 
_refine_hist.number_atoms_total               2576 
_refine_hist.d_res_high                       2.371 
_refine_hist.d_res_low                        60.61 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  2607 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  2365 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.661  1.827  3537 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.578  1.767  5463 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.670  5.000  312  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 9.856  5.000  5    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.146 10.000 422  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.764 10.000 131  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.093  0.200  369  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  3043 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  585  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.220  0.200  516  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200  2147 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.187  0.200  1286 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.091  0.200  1304 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.190  0.200  70   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.114  0.200  15   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.252  0.200  73   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.129  0.200  5    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 5.788  6.323  1254 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.783  6.322  1254 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 7.331  11.359 1564 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.329  11.358 1565 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 6.247  6.740  1353 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.245  6.739  1354 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 8.360  12.242 1973 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.358  12.241 1974 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 9.610  61.251 2914 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 9.613  61.258 2912 ? r_lrange_other                 ? ? 
'X-RAY DIFFRACTION' ? 0.075  0.050  5103 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.07536 ? 0.05009 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.07536 ? 0.05009 2 'Local ncs' ? A ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.37  60.61  . . 16 275  100.0000 . . . . 0.241 . . . . . . . . . . . 0.252 
'X-RAY DIFFRACTION' 2.371 2.432  . . 67 1532 99.8751  . . . . 0.250 . . . . . . . . . . . 0.370 
'X-RAY DIFFRACTION' 2.432 2.499  . . 78 1500 100.0000 . . . . 0.254 . . . . . . . . . . . 0.281 
'X-RAY DIFFRACTION' 2.499 2.571  . . 89 1472 100.0000 . . . . 0.272 . . . . . . . . . . . 0.350 
'X-RAY DIFFRACTION' 2.571 2.650  . . 46 1452 100.0000 . . . . 0.268 . . . . . . . . . . . 0.329 
'X-RAY DIFFRACTION' 2.650 2.737  . . 59 1393 100.0000 . . . . 0.261 . . . . . . . . . . . 0.384 
'X-RAY DIFFRACTION' 2.737 2.832  . . 72 1335 100.0000 . . . . 0.233 . . . . . . . . . . . 0.289 
'X-RAY DIFFRACTION' 2.832 2.939  . . 77 1279 100.0000 . . . . 0.220 . . . . . . . . . . . 0.223 
'X-RAY DIFFRACTION' 2.939 3.059  . . 58 1245 100.0000 . . . . 0.214 . . . . . . . . . . . 0.281 
'X-RAY DIFFRACTION' 3.059 3.195  . . 77 1190 100.0000 . . . . 0.230 . . . . . . . . . . . 0.254 
'X-RAY DIFFRACTION' 3.195 3.350  . . 69 1130 100.0000 . . . . 0.226 . . . . . . . . . . . 0.244 
'X-RAY DIFFRACTION' 3.350 3.531  . . 48 1090 100.0000 . . . . 0.213 . . . . . . . . . . . 0.228 
'X-RAY DIFFRACTION' 3.531 3.744  . . 54 1042 100.0000 . . . . 0.199 . . . . . . . . . . . 0.230 
'X-RAY DIFFRACTION' 3.744 4.001  . . 58 964  100.0000 . . . . 0.180 . . . . . . . . . . . 0.184 
'X-RAY DIFFRACTION' 4.001 4.320  . . 50 908  100.0000 . . . . 0.172 . . . . . . . . . . . 0.194 
'X-RAY DIFFRACTION' 4.320 4.730  . . 55 831  100.0000 . . . . 0.156 . . . . . . . . . . . 0.208 
'X-RAY DIFFRACTION' 4.730 5.285  . . 46 753  100.0000 . . . . 0.177 . . . . . . . . . . . 0.199 
'X-RAY DIFFRACTION' 5.285 6.095  . . 32 683  100.0000 . . . . 0.196 . . . . . . . . . . . 0.246 
'X-RAY DIFFRACTION' 6.095 7.446  . . 31 579  100.0000 . . . . 0.182 . . . . . . . . . . . 0.238 
'X-RAY DIFFRACTION' 7.446 10.451 . . 33 444  100.0000 . . . . 0.159 . . . . . . . . . . . 0.177 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 A 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A MET 1 . A TYR 157 . A MET 1 A TYR 157 ? ? 
1 2 1 A MET 1 . A TYR 157 . A MET 1 A TYR 157 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9F08 
_struct.title                        
;Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Covalent complex with 2-deoxyribose.
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9F08 
_struct_keywords.text            
;Nucleoside-2'-deoxyribosyltransferase, TRANSFERASE
;
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    NTD_LACLE 
_struct_ref.pdbx_db_accession          Q9R5V5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTND
IMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9F08 A 1 ? 157 ? Q9R5V5 1 ? 157 ? 1 157 
2 1 9F08 B 1 ? 157 ? Q9R5V5 1 ? 157 ? 1 157 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 17310 ? 
1 MORE         -132  ? 
1 'SSA (A^2)'  32640 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2,3 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555  x,y,z           1.0000000000 0.0000000000  0.0000000000  0.0000000000  0.0000000000  
1.0000000000 0.0000000000 0.0000000000   0.0000000000  0.0000000000 1.0000000000 0.0000000000  
2 'crystal symmetry operation' 7_555  -z+1/2,-x,y+1/2 0.0000000000 0.0000000000  -1.0000000000 74.2305000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000   0.0000000000  1.0000000000 0.0000000000 74.2305000000 
3 'crystal symmetry operation' 10_545 -y,z-1/2,-x+1/2 0.0000000000 -1.0000000000 0.0000000000  0.0000000000  0.0000000000  
0.0000000000 1.0000000000 -74.2305000000 -1.0000000000 0.0000000000 0.0000000000 74.2305000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 14  ? GLU A 30  ? THR A 14  GLU A 30  1 ? 17 
HELX_P HELX_P2  AA2 ASP A 35  ? SER A 39  ? ASP A 35  SER A 39  5 ? 5  
HELX_P HELX_P3  AA3 VAL A 41  ? ASN A 45  ? VAL A 41  ASN A 45  5 ? 5  
HELX_P HELX_P4  AA4 GLN A 46  ? ILE A 50  ? GLN A 46  ILE A 50  5 ? 5  
HELX_P HELX_P5  AA5 HIS A 55  ? HIS A 60  ? HIS A 55  HIS A 60  5 ? 6  
HELX_P HELX_P6  AA6 ASP A 61  ? THR A 78  ? ASP A 61  THR A 78  1 ? 18 
HELX_P HELX_P7  AA7 ASP A 92  ? GLN A 105 ? ASP A 92  GLN A 105 1 ? 14 
HELX_P HELX_P8  AA8 ASN A 123 ? SER A 130 ? ASN A 123 SER A 130 1 ? 8  
HELX_P HELX_P9  AA9 SER A 137 ? PHE A 142 ? SER A 137 PHE A 142 5 ? 6  
HELX_P HELX_P10 AB1 THR B 14  ? GLU B 30  ? THR B 14  GLU B 30  1 ? 17 
HELX_P HELX_P11 AB2 ASP B 35  ? SER B 39  ? ASP B 35  SER B 39  5 ? 5  
HELX_P HELX_P12 AB3 VAL B 41  ? ASN B 45  ? VAL B 41  ASN B 45  5 ? 5  
HELX_P HELX_P13 AB4 GLN B 46  ? ILE B 50  ? GLN B 46  ILE B 50  5 ? 5  
HELX_P HELX_P14 AB5 HIS B 55  ? HIS B 60  ? HIS B 55  HIS B 60  5 ? 6  
HELX_P HELX_P15 AB6 ASP B 61  ? THR B 78  ? ASP B 61  THR B 78  1 ? 18 
HELX_P HELX_P16 AB7 ASP B 92  ? GLN B 105 ? ASP B 92  GLN B 105 1 ? 14 
HELX_P HELX_P17 AB8 ASN B 123 ? SER B 130 ? ASN B 123 SER B 130 1 ? 8  
HELX_P HELX_P18 AB9 SER B 137 ? PHE B 142 ? SER B 137 PHE B 142 5 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale one ? A GLU 98 OE2 ? ? ? 1_555 C 2DR . C1 ? ? A GLU 98 A 2DR 201 1_555 ? ? ? ? ? ? ? 1.469 ? ? 
covale2 covale one ? B GLU 98 OE2 ? ? ? 1_555 D 2DR . C1 ? ? B GLU 98 B 2DR 201 1_555 ? ? ? ? ? ? ? 1.477 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 2DR C . ? GLU A 98 ? 2DR A 201 ? 1_555 GLU A 98 ? 1_555 C1 OE2 GLU 2 2DR None Carbohydrate 
2 2DR D . ? GLU B 98 ? 2DR B 201 ? 1_555 GLU B 98 ? 1_555 C1 OE2 GLU 2 2DR None Carbohydrate 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 6   ? ALA A 10  ? ILE A 6   ALA A 10  
AA1 2 ILE A 81  ? VAL A 85  ? ILE A 81  VAL A 85  
AA1 3 TYR A 108 ? ILE A 113 ? TYR A 108 ILE A 113 
AA1 4 ASN A 132 ? LYS A 135 ? ASN A 132 LYS A 135 
AA2 1 ILE B 6   ? ALA B 10  ? ILE B 6   ALA B 10  
AA2 2 ILE B 81  ? VAL B 85  ? ILE B 81  VAL B 85  
AA2 3 TYR B 108 ? ILE B 113 ? TYR B 108 ILE B 113 
AA2 4 ASN B 132 ? LYS B 135 ? ASN B 132 LYS B 135 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 9   ? N GLY A 9   O VAL A 85  ? O VAL A 85  
AA1 2 3 N MET A 82  ? N MET A 82  O LEU A 110 ? O LEU A 110 
AA1 3 4 N LEU A 111 ? N LEU A 111 O ILE A 134 ? O ILE A 134 
AA2 1 2 N GLY B 9   ? N GLY B 9   O VAL B 85  ? O VAL B 85  
AA2 2 3 N MET B 82  ? N MET B 82  O LEU B 110 ? O LEU B 110 
AA2 3 4 N ILE B 113 ? N ILE B 113 O ILE B 134 ? O ILE B 134 
# 
_pdbx_entry_details.entry_id                   9F08 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   ASN 
_pdbx_validate_close_contact.auth_seq_id_1    38 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    301 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.15 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PRO A 56 ? ? -55.46  -5.20  
2 1 ALA B 10 ? ? -170.74 133.00 
3 1 TRP B 12 ? ? -140.94 33.52  
4 1 PRO B 56 ? ? -59.66  -6.02  
# 
loop_
_pdbx_validate_chiral.id 
_pdbx_validate_chiral.PDB_model_num 
_pdbx_validate_chiral.auth_atom_id 
_pdbx_validate_chiral.label_alt_id 
_pdbx_validate_chiral.auth_asym_id 
_pdbx_validate_chiral.auth_comp_id 
_pdbx_validate_chiral.auth_seq_id 
_pdbx_validate_chiral.PDB_ins_code 
_pdbx_validate_chiral.details 
_pdbx_validate_chiral.omega 
1 1 C1 ? A 2DR 201 ? 'WRONG HAND' . 
2 1 C1 ? B 2DR 201 ? 'WRONG HAND' . 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    B 
_pdbx_validate_planes.auth_seq_id     148 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.083 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
2DR C2   C N N 1   
2DR C3   C N S 2   
2DR C4   C N R 3   
2DR C5   C N N 4   
2DR O1   O N N 5   
2DR O3   O N N 6   
2DR O4   O N N 7   
2DR O5   O N N 8   
2DR C1   C N R 9   
2DR H2   H N N 10  
2DR H22C H N N 11  
2DR H3   H N N 12  
2DR H1   H N N 13  
2DR H4   H N N 14  
2DR HO3  H N N 15  
2DR H51  H N N 16  
2DR H52  H N N 17  
2DR HO5  H N N 18  
2DR HO1  H N N 19  
ALA N    N N N 20  
ALA CA   C N S 21  
ALA C    C N N 22  
ALA O    O N N 23  
ALA CB   C N N 24  
ALA OXT  O N N 25  
ALA H    H N N 26  
ALA H2   H N N 27  
ALA HA   H N N 28  
ALA HB1  H N N 29  
ALA HB2  H N N 30  
ALA HB3  H N N 31  
ALA HXT  H N N 32  
ARG N    N N N 33  
ARG CA   C N S 34  
ARG C    C N N 35  
ARG O    O N N 36  
ARG CB   C N N 37  
ARG CG   C N N 38  
ARG CD   C N N 39  
ARG NE   N N N 40  
ARG CZ   C N N 41  
ARG NH1  N N N 42  
ARG NH2  N N N 43  
ARG OXT  O N N 44  
ARG H    H N N 45  
ARG H2   H N N 46  
ARG HA   H N N 47  
ARG HB2  H N N 48  
ARG HB3  H N N 49  
ARG HG2  H N N 50  
ARG HG3  H N N 51  
ARG HD2  H N N 52  
ARG HD3  H N N 53  
ARG HE   H N N 54  
ARG HH11 H N N 55  
ARG HH12 H N N 56  
ARG HH21 H N N 57  
ARG HH22 H N N 58  
ARG HXT  H N N 59  
ASN N    N N N 60  
ASN CA   C N S 61  
ASN C    C N N 62  
ASN O    O N N 63  
ASN CB   C N N 64  
ASN CG   C N N 65  
ASN OD1  O N N 66  
ASN ND2  N N N 67  
ASN OXT  O N N 68  
ASN H    H N N 69  
ASN H2   H N N 70  
ASN HA   H N N 71  
ASN HB2  H N N 72  
ASN HB3  H N N 73  
ASN HD21 H N N 74  
ASN HD22 H N N 75  
ASN HXT  H N N 76  
ASP N    N N N 77  
ASP CA   C N S 78  
ASP C    C N N 79  
ASP O    O N N 80  
ASP CB   C N N 81  
ASP CG   C N N 82  
ASP OD1  O N N 83  
ASP OD2  O N N 84  
ASP OXT  O N N 85  
ASP H    H N N 86  
ASP H2   H N N 87  
ASP HA   H N N 88  
ASP HB2  H N N 89  
ASP HB3  H N N 90  
ASP HD2  H N N 91  
ASP HXT  H N N 92  
GLN N    N N N 93  
GLN CA   C N S 94  
GLN C    C N N 95  
GLN O    O N N 96  
GLN CB   C N N 97  
GLN CG   C N N 98  
GLN CD   C N N 99  
GLN OE1  O N N 100 
GLN NE2  N N N 101 
GLN OXT  O N N 102 
GLN H    H N N 103 
GLN H2   H N N 104 
GLN HA   H N N 105 
GLN HB2  H N N 106 
GLN HB3  H N N 107 
GLN HG2  H N N 108 
GLN HG3  H N N 109 
GLN HE21 H N N 110 
GLN HE22 H N N 111 
GLN HXT  H N N 112 
GLU N    N N N 113 
GLU CA   C N S 114 
GLU C    C N N 115 
GLU O    O N N 116 
GLU CB   C N N 117 
GLU CG   C N N 118 
GLU CD   C N N 119 
GLU OE1  O N N 120 
GLU OE2  O N N 121 
GLU OXT  O N N 122 
GLU H    H N N 123 
GLU H2   H N N 124 
GLU HA   H N N 125 
GLU HB2  H N N 126 
GLU HB3  H N N 127 
GLU HG2  H N N 128 
GLU HG3  H N N 129 
GLU HE2  H N N 130 
GLU HXT  H N N 131 
GLY N    N N N 132 
GLY CA   C N N 133 
GLY C    C N N 134 
GLY O    O N N 135 
GLY OXT  O N N 136 
GLY H    H N N 137 
GLY H2   H N N 138 
GLY HA2  H N N 139 
GLY HA3  H N N 140 
GLY HXT  H N N 141 
HIS N    N N N 142 
HIS CA   C N S 143 
HIS C    C N N 144 
HIS O    O N N 145 
HIS CB   C N N 146 
HIS CG   C Y N 147 
HIS ND1  N Y N 148 
HIS CD2  C Y N 149 
HIS CE1  C Y N 150 
HIS NE2  N Y N 151 
HIS OXT  O N N 152 
HIS H    H N N 153 
HIS H2   H N N 154 
HIS HA   H N N 155 
HIS HB2  H N N 156 
HIS HB3  H N N 157 
HIS HD1  H N N 158 
HIS HD2  H N N 159 
HIS HE1  H N N 160 
HIS HE2  H N N 161 
HIS HXT  H N N 162 
HOH O    O N N 163 
HOH H1   H N N 164 
HOH H2   H N N 165 
ILE N    N N N 166 
ILE CA   C N S 167 
ILE C    C N N 168 
ILE O    O N N 169 
ILE CB   C N S 170 
ILE CG1  C N N 171 
ILE CG2  C N N 172 
ILE CD1  C N N 173 
ILE OXT  O N N 174 
ILE H    H N N 175 
ILE H2   H N N 176 
ILE HA   H N N 177 
ILE HB   H N N 178 
ILE HG12 H N N 179 
ILE HG13 H N N 180 
ILE HG21 H N N 181 
ILE HG22 H N N 182 
ILE HG23 H N N 183 
ILE HD11 H N N 184 
ILE HD12 H N N 185 
ILE HD13 H N N 186 
ILE HXT  H N N 187 
LEU N    N N N 188 
LEU CA   C N S 189 
LEU C    C N N 190 
LEU O    O N N 191 
LEU CB   C N N 192 
LEU CG   C N N 193 
LEU CD1  C N N 194 
LEU CD2  C N N 195 
LEU OXT  O N N 196 
LEU H    H N N 197 
LEU H2   H N N 198 
LEU HA   H N N 199 
LEU HB2  H N N 200 
LEU HB3  H N N 201 
LEU HG   H N N 202 
LEU HD11 H N N 203 
LEU HD12 H N N 204 
LEU HD13 H N N 205 
LEU HD21 H N N 206 
LEU HD22 H N N 207 
LEU HD23 H N N 208 
LEU HXT  H N N 209 
LYS N    N N N 210 
LYS CA   C N S 211 
LYS C    C N N 212 
LYS O    O N N 213 
LYS CB   C N N 214 
LYS CG   C N N 215 
LYS CD   C N N 216 
LYS CE   C N N 217 
LYS NZ   N N N 218 
LYS OXT  O N N 219 
LYS H    H N N 220 
LYS H2   H N N 221 
LYS HA   H N N 222 
LYS HB2  H N N 223 
LYS HB3  H N N 224 
LYS HG2  H N N 225 
LYS HG3  H N N 226 
LYS HD2  H N N 227 
LYS HD3  H N N 228 
LYS HE2  H N N 229 
LYS HE3  H N N 230 
LYS HZ1  H N N 231 
LYS HZ2  H N N 232 
LYS HZ3  H N N 233 
LYS HXT  H N N 234 
MET N    N N N 235 
MET CA   C N S 236 
MET C    C N N 237 
MET O    O N N 238 
MET CB   C N N 239 
MET CG   C N N 240 
MET SD   S N N 241 
MET CE   C N N 242 
MET OXT  O N N 243 
MET H    H N N 244 
MET H2   H N N 245 
MET HA   H N N 246 
MET HB2  H N N 247 
MET HB3  H N N 248 
MET HG2  H N N 249 
MET HG3  H N N 250 
MET HE1  H N N 251 
MET HE2  H N N 252 
MET HE3  H N N 253 
MET HXT  H N N 254 
PHE N    N N N 255 
PHE CA   C N S 256 
PHE C    C N N 257 
PHE O    O N N 258 
PHE CB   C N N 259 
PHE CG   C Y N 260 
PHE CD1  C Y N 261 
PHE CD2  C Y N 262 
PHE CE1  C Y N 263 
PHE CE2  C Y N 264 
PHE CZ   C Y N 265 
PHE OXT  O N N 266 
PHE H    H N N 267 
PHE H2   H N N 268 
PHE HA   H N N 269 
PHE HB2  H N N 270 
PHE HB3  H N N 271 
PHE HD1  H N N 272 
PHE HD2  H N N 273 
PHE HE1  H N N 274 
PHE HE2  H N N 275 
PHE HZ   H N N 276 
PHE HXT  H N N 277 
PRO N    N N N 278 
PRO CA   C N S 279 
PRO C    C N N 280 
PRO O    O N N 281 
PRO CB   C N N 282 
PRO CG   C N N 283 
PRO CD   C N N 284 
PRO OXT  O N N 285 
PRO H    H N N 286 
PRO HA   H N N 287 
PRO HB2  H N N 288 
PRO HB3  H N N 289 
PRO HG2  H N N 290 
PRO HG3  H N N 291 
PRO HD2  H N N 292 
PRO HD3  H N N 293 
PRO HXT  H N N 294 
SER N    N N N 295 
SER CA   C N S 296 
SER C    C N N 297 
SER O    O N N 298 
SER CB   C N N 299 
SER OG   O N N 300 
SER OXT  O N N 301 
SER H    H N N 302 
SER H2   H N N 303 
SER HA   H N N 304 
SER HB2  H N N 305 
SER HB3  H N N 306 
SER HG   H N N 307 
SER HXT  H N N 308 
THR N    N N N 309 
THR CA   C N S 310 
THR C    C N N 311 
THR O    O N N 312 
THR CB   C N R 313 
THR OG1  O N N 314 
THR CG2  C N N 315 
THR OXT  O N N 316 
THR H    H N N 317 
THR H2   H N N 318 
THR HA   H N N 319 
THR HB   H N N 320 
THR HG1  H N N 321 
THR HG21 H N N 322 
THR HG22 H N N 323 
THR HG23 H N N 324 
THR HXT  H N N 325 
TRP N    N N N 326 
TRP CA   C N S 327 
TRP C    C N N 328 
TRP O    O N N 329 
TRP CB   C N N 330 
TRP CG   C Y N 331 
TRP CD1  C Y N 332 
TRP CD2  C Y N 333 
TRP NE1  N Y N 334 
TRP CE2  C Y N 335 
TRP CE3  C Y N 336 
TRP CZ2  C Y N 337 
TRP CZ3  C Y N 338 
TRP CH2  C Y N 339 
TRP OXT  O N N 340 
TRP H    H N N 341 
TRP H2   H N N 342 
TRP HA   H N N 343 
TRP HB2  H N N 344 
TRP HB3  H N N 345 
TRP HD1  H N N 346 
TRP HE1  H N N 347 
TRP HE3  H N N 348 
TRP HZ2  H N N 349 
TRP HZ3  H N N 350 
TRP HH2  H N N 351 
TRP HXT  H N N 352 
TYR N    N N N 353 
TYR CA   C N S 354 
TYR C    C N N 355 
TYR O    O N N 356 
TYR CB   C N N 357 
TYR CG   C Y N 358 
TYR CD1  C Y N 359 
TYR CD2  C Y N 360 
TYR CE1  C Y N 361 
TYR CE2  C Y N 362 
TYR CZ   C Y N 363 
TYR OH   O N N 364 
TYR OXT  O N N 365 
TYR H    H N N 366 
TYR H2   H N N 367 
TYR HA   H N N 368 
TYR HB2  H N N 369 
TYR HB3  H N N 370 
TYR HD1  H N N 371 
TYR HD2  H N N 372 
TYR HE1  H N N 373 
TYR HE2  H N N 374 
TYR HH   H N N 375 
TYR HXT  H N N 376 
VAL N    N N N 377 
VAL CA   C N S 378 
VAL C    C N N 379 
VAL O    O N N 380 
VAL CB   C N N 381 
VAL CG1  C N N 382 
VAL CG2  C N N 383 
VAL OXT  O N N 384 
VAL H    H N N 385 
VAL H2   H N N 386 
VAL HA   H N N 387 
VAL HB   H N N 388 
VAL HG11 H N N 389 
VAL HG12 H N N 390 
VAL HG13 H N N 391 
VAL HG21 H N N 392 
VAL HG22 H N N 393 
VAL HG23 H N N 394 
VAL HXT  H N N 395 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
2DR C2  C3   sing N N 1   
2DR C2  C1   sing N N 2   
2DR C3  C4   sing N N 3   
2DR C3  O3   sing N N 4   
2DR C4  C5   sing N N 5   
2DR C4  O4   sing N N 6   
2DR C5  O5   sing N N 7   
2DR O1  C1   sing N N 8   
2DR O4  C1   sing N N 9   
2DR C2  H2   sing N N 10  
2DR C2  H22C sing N N 11  
2DR C3  H3   sing N N 12  
2DR C1  H1   sing N N 13  
2DR C4  H4   sing N N 14  
2DR O3  HO3  sing N N 15  
2DR C5  H51  sing N N 16  
2DR C5  H52  sing N N 17  
2DR O5  HO5  sing N N 18  
2DR O1  HO1  sing N N 19  
ALA N   CA   sing N N 20  
ALA N   H    sing N N 21  
ALA N   H2   sing N N 22  
ALA CA  C    sing N N 23  
ALA CA  CB   sing N N 24  
ALA CA  HA   sing N N 25  
ALA C   O    doub N N 26  
ALA C   OXT  sing N N 27  
ALA CB  HB1  sing N N 28  
ALA CB  HB2  sing N N 29  
ALA CB  HB3  sing N N 30  
ALA OXT HXT  sing N N 31  
ARG N   CA   sing N N 32  
ARG N   H    sing N N 33  
ARG N   H2   sing N N 34  
ARG CA  C    sing N N 35  
ARG CA  CB   sing N N 36  
ARG CA  HA   sing N N 37  
ARG C   O    doub N N 38  
ARG C   OXT  sing N N 39  
ARG CB  CG   sing N N 40  
ARG CB  HB2  sing N N 41  
ARG CB  HB3  sing N N 42  
ARG CG  CD   sing N N 43  
ARG CG  HG2  sing N N 44  
ARG CG  HG3  sing N N 45  
ARG CD  NE   sing N N 46  
ARG CD  HD2  sing N N 47  
ARG CD  HD3  sing N N 48  
ARG NE  CZ   sing N N 49  
ARG NE  HE   sing N N 50  
ARG CZ  NH1  sing N N 51  
ARG CZ  NH2  doub N N 52  
ARG NH1 HH11 sing N N 53  
ARG NH1 HH12 sing N N 54  
ARG NH2 HH21 sing N N 55  
ARG NH2 HH22 sing N N 56  
ARG OXT HXT  sing N N 57  
ASN N   CA   sing N N 58  
ASN N   H    sing N N 59  
ASN N   H2   sing N N 60  
ASN CA  C    sing N N 61  
ASN CA  CB   sing N N 62  
ASN CA  HA   sing N N 63  
ASN C   O    doub N N 64  
ASN C   OXT  sing N N 65  
ASN CB  CG   sing N N 66  
ASN CB  HB2  sing N N 67  
ASN CB  HB3  sing N N 68  
ASN CG  OD1  doub N N 69  
ASN CG  ND2  sing N N 70  
ASN ND2 HD21 sing N N 71  
ASN ND2 HD22 sing N N 72  
ASN OXT HXT  sing N N 73  
ASP N   CA   sing N N 74  
ASP N   H    sing N N 75  
ASP N   H2   sing N N 76  
ASP CA  C    sing N N 77  
ASP CA  CB   sing N N 78  
ASP CA  HA   sing N N 79  
ASP C   O    doub N N 80  
ASP C   OXT  sing N N 81  
ASP CB  CG   sing N N 82  
ASP CB  HB2  sing N N 83  
ASP CB  HB3  sing N N 84  
ASP CG  OD1  doub N N 85  
ASP CG  OD2  sing N N 86  
ASP OD2 HD2  sing N N 87  
ASP OXT HXT  sing N N 88  
GLN N   CA   sing N N 89  
GLN N   H    sing N N 90  
GLN N   H2   sing N N 91  
GLN CA  C    sing N N 92  
GLN CA  CB   sing N N 93  
GLN CA  HA   sing N N 94  
GLN C   O    doub N N 95  
GLN C   OXT  sing N N 96  
GLN CB  CG   sing N N 97  
GLN CB  HB2  sing N N 98  
GLN CB  HB3  sing N N 99  
GLN CG  CD   sing N N 100 
GLN CG  HG2  sing N N 101 
GLN CG  HG3  sing N N 102 
GLN CD  OE1  doub N N 103 
GLN CD  NE2  sing N N 104 
GLN NE2 HE21 sing N N 105 
GLN NE2 HE22 sing N N 106 
GLN OXT HXT  sing N N 107 
GLU N   CA   sing N N 108 
GLU N   H    sing N N 109 
GLU N   H2   sing N N 110 
GLU CA  C    sing N N 111 
GLU CA  CB   sing N N 112 
GLU CA  HA   sing N N 113 
GLU C   O    doub N N 114 
GLU C   OXT  sing N N 115 
GLU CB  CG   sing N N 116 
GLU CB  HB2  sing N N 117 
GLU CB  HB3  sing N N 118 
GLU CG  CD   sing N N 119 
GLU CG  HG2  sing N N 120 
GLU CG  HG3  sing N N 121 
GLU CD  OE1  doub N N 122 
GLU CD  OE2  sing N N 123 
GLU OE2 HE2  sing N N 124 
GLU OXT HXT  sing N N 125 
GLY N   CA   sing N N 126 
GLY N   H    sing N N 127 
GLY N   H2   sing N N 128 
GLY CA  C    sing N N 129 
GLY CA  HA2  sing N N 130 
GLY CA  HA3  sing N N 131 
GLY C   O    doub N N 132 
GLY C   OXT  sing N N 133 
GLY OXT HXT  sing N N 134 
HIS N   CA   sing N N 135 
HIS N   H    sing N N 136 
HIS N   H2   sing N N 137 
HIS CA  C    sing N N 138 
HIS CA  CB   sing N N 139 
HIS CA  HA   sing N N 140 
HIS C   O    doub N N 141 
HIS C   OXT  sing N N 142 
HIS CB  CG   sing N N 143 
HIS CB  HB2  sing N N 144 
HIS CB  HB3  sing N N 145 
HIS CG  ND1  sing Y N 146 
HIS CG  CD2  doub Y N 147 
HIS ND1 CE1  doub Y N 148 
HIS ND1 HD1  sing N N 149 
HIS CD2 NE2  sing Y N 150 
HIS CD2 HD2  sing N N 151 
HIS CE1 NE2  sing Y N 152 
HIS CE1 HE1  sing N N 153 
HIS NE2 HE2  sing N N 154 
HIS OXT HXT  sing N N 155 
HOH O   H1   sing N N 156 
HOH O   H2   sing N N 157 
ILE N   CA   sing N N 158 
ILE N   H    sing N N 159 
ILE N   H2   sing N N 160 
ILE CA  C    sing N N 161 
ILE CA  CB   sing N N 162 
ILE CA  HA   sing N N 163 
ILE C   O    doub N N 164 
ILE C   OXT  sing N N 165 
ILE CB  CG1  sing N N 166 
ILE CB  CG2  sing N N 167 
ILE CB  HB   sing N N 168 
ILE CG1 CD1  sing N N 169 
ILE CG1 HG12 sing N N 170 
ILE CG1 HG13 sing N N 171 
ILE CG2 HG21 sing N N 172 
ILE CG2 HG22 sing N N 173 
ILE CG2 HG23 sing N N 174 
ILE CD1 HD11 sing N N 175 
ILE CD1 HD12 sing N N 176 
ILE CD1 HD13 sing N N 177 
ILE OXT HXT  sing N N 178 
LEU N   CA   sing N N 179 
LEU N   H    sing N N 180 
LEU N   H2   sing N N 181 
LEU CA  C    sing N N 182 
LEU CA  CB   sing N N 183 
LEU CA  HA   sing N N 184 
LEU C   O    doub N N 185 
LEU C   OXT  sing N N 186 
LEU CB  CG   sing N N 187 
LEU CB  HB2  sing N N 188 
LEU CB  HB3  sing N N 189 
LEU CG  CD1  sing N N 190 
LEU CG  CD2  sing N N 191 
LEU CG  HG   sing N N 192 
LEU CD1 HD11 sing N N 193 
LEU CD1 HD12 sing N N 194 
LEU CD1 HD13 sing N N 195 
LEU CD2 HD21 sing N N 196 
LEU CD2 HD22 sing N N 197 
LEU CD2 HD23 sing N N 198 
LEU OXT HXT  sing N N 199 
LYS N   CA   sing N N 200 
LYS N   H    sing N N 201 
LYS N   H2   sing N N 202 
LYS CA  C    sing N N 203 
LYS CA  CB   sing N N 204 
LYS CA  HA   sing N N 205 
LYS C   O    doub N N 206 
LYS C   OXT  sing N N 207 
LYS CB  CG   sing N N 208 
LYS CB  HB2  sing N N 209 
LYS CB  HB3  sing N N 210 
LYS CG  CD   sing N N 211 
LYS CG  HG2  sing N N 212 
LYS CG  HG3  sing N N 213 
LYS CD  CE   sing N N 214 
LYS CD  HD2  sing N N 215 
LYS CD  HD3  sing N N 216 
LYS CE  NZ   sing N N 217 
LYS CE  HE2  sing N N 218 
LYS CE  HE3  sing N N 219 
LYS NZ  HZ1  sing N N 220 
LYS NZ  HZ2  sing N N 221 
LYS NZ  HZ3  sing N N 222 
LYS OXT HXT  sing N N 223 
MET N   CA   sing N N 224 
MET N   H    sing N N 225 
MET N   H2   sing N N 226 
MET CA  C    sing N N 227 
MET CA  CB   sing N N 228 
MET CA  HA   sing N N 229 
MET C   O    doub N N 230 
MET C   OXT  sing N N 231 
MET CB  CG   sing N N 232 
MET CB  HB2  sing N N 233 
MET CB  HB3  sing N N 234 
MET CG  SD   sing N N 235 
MET CG  HG2  sing N N 236 
MET CG  HG3  sing N N 237 
MET SD  CE   sing N N 238 
MET CE  HE1  sing N N 239 
MET CE  HE2  sing N N 240 
MET CE  HE3  sing N N 241 
MET OXT HXT  sing N N 242 
PHE N   CA   sing N N 243 
PHE N   H    sing N N 244 
PHE N   H2   sing N N 245 
PHE CA  C    sing N N 246 
PHE CA  CB   sing N N 247 
PHE CA  HA   sing N N 248 
PHE C   O    doub N N 249 
PHE C   OXT  sing N N 250 
PHE CB  CG   sing N N 251 
PHE CB  HB2  sing N N 252 
PHE CB  HB3  sing N N 253 
PHE CG  CD1  doub Y N 254 
PHE CG  CD2  sing Y N 255 
PHE CD1 CE1  sing Y N 256 
PHE CD1 HD1  sing N N 257 
PHE CD2 CE2  doub Y N 258 
PHE CD2 HD2  sing N N 259 
PHE CE1 CZ   doub Y N 260 
PHE CE1 HE1  sing N N 261 
PHE CE2 CZ   sing Y N 262 
PHE CE2 HE2  sing N N 263 
PHE CZ  HZ   sing N N 264 
PHE OXT HXT  sing N N 265 
PRO N   CA   sing N N 266 
PRO N   CD   sing N N 267 
PRO N   H    sing N N 268 
PRO CA  C    sing N N 269 
PRO CA  CB   sing N N 270 
PRO CA  HA   sing N N 271 
PRO C   O    doub N N 272 
PRO C   OXT  sing N N 273 
PRO CB  CG   sing N N 274 
PRO CB  HB2  sing N N 275 
PRO CB  HB3  sing N N 276 
PRO CG  CD   sing N N 277 
PRO CG  HG2  sing N N 278 
PRO CG  HG3  sing N N 279 
PRO CD  HD2  sing N N 280 
PRO CD  HD3  sing N N 281 
PRO OXT HXT  sing N N 282 
SER N   CA   sing N N 283 
SER N   H    sing N N 284 
SER N   H2   sing N N 285 
SER CA  C    sing N N 286 
SER CA  CB   sing N N 287 
SER CA  HA   sing N N 288 
SER C   O    doub N N 289 
SER C   OXT  sing N N 290 
SER CB  OG   sing N N 291 
SER CB  HB2  sing N N 292 
SER CB  HB3  sing N N 293 
SER OG  HG   sing N N 294 
SER OXT HXT  sing N N 295 
THR N   CA   sing N N 296 
THR N   H    sing N N 297 
THR N   H2   sing N N 298 
THR CA  C    sing N N 299 
THR CA  CB   sing N N 300 
THR CA  HA   sing N N 301 
THR C   O    doub N N 302 
THR C   OXT  sing N N 303 
THR CB  OG1  sing N N 304 
THR CB  CG2  sing N N 305 
THR CB  HB   sing N N 306 
THR OG1 HG1  sing N N 307 
THR CG2 HG21 sing N N 308 
THR CG2 HG22 sing N N 309 
THR CG2 HG23 sing N N 310 
THR OXT HXT  sing N N 311 
TRP N   CA   sing N N 312 
TRP N   H    sing N N 313 
TRP N   H2   sing N N 314 
TRP CA  C    sing N N 315 
TRP CA  CB   sing N N 316 
TRP CA  HA   sing N N 317 
TRP C   O    doub N N 318 
TRP C   OXT  sing N N 319 
TRP CB  CG   sing N N 320 
TRP CB  HB2  sing N N 321 
TRP CB  HB3  sing N N 322 
TRP CG  CD1  doub Y N 323 
TRP CG  CD2  sing Y N 324 
TRP CD1 NE1  sing Y N 325 
TRP CD1 HD1  sing N N 326 
TRP CD2 CE2  doub Y N 327 
TRP CD2 CE3  sing Y N 328 
TRP NE1 CE2  sing Y N 329 
TRP NE1 HE1  sing N N 330 
TRP CE2 CZ2  sing Y N 331 
TRP CE3 CZ3  doub Y N 332 
TRP CE3 HE3  sing N N 333 
TRP CZ2 CH2  doub Y N 334 
TRP CZ2 HZ2  sing N N 335 
TRP CZ3 CH2  sing Y N 336 
TRP CZ3 HZ3  sing N N 337 
TRP CH2 HH2  sing N N 338 
TRP OXT HXT  sing N N 339 
TYR N   CA   sing N N 340 
TYR N   H    sing N N 341 
TYR N   H2   sing N N 342 
TYR CA  C    sing N N 343 
TYR CA  CB   sing N N 344 
TYR CA  HA   sing N N 345 
TYR C   O    doub N N 346 
TYR C   OXT  sing N N 347 
TYR CB  CG   sing N N 348 
TYR CB  HB2  sing N N 349 
TYR CB  HB3  sing N N 350 
TYR CG  CD1  doub Y N 351 
TYR CG  CD2  sing Y N 352 
TYR CD1 CE1  sing Y N 353 
TYR CD1 HD1  sing N N 354 
TYR CD2 CE2  doub Y N 355 
TYR CD2 HD2  sing N N 356 
TYR CE1 CZ   doub Y N 357 
TYR CE1 HE1  sing N N 358 
TYR CE2 CZ   sing Y N 359 
TYR CE2 HE2  sing N N 360 
TYR CZ  OH   sing N N 361 
TYR OH  HH   sing N N 362 
TYR OXT HXT  sing N N 363 
VAL N   CA   sing N N 364 
VAL N   H    sing N N 365 
VAL N   H2   sing N N 366 
VAL CA  C    sing N N 367 
VAL CA  CB   sing N N 368 
VAL CA  HA   sing N N 369 
VAL C   O    doub N N 370 
VAL C   OXT  sing N N 371 
VAL CB  CG1  sing N N 372 
VAL CB  CG2  sing N N 373 
VAL CB  HB   sing N N 374 
VAL CG1 HG11 sing N N 375 
VAL CG1 HG12 sing N N 376 
VAL CG1 HG13 sing N N 377 
VAL CG2 HG21 sing N N 378 
VAL CG2 HG22 sing N N 379 
VAL CG2 HG23 sing N N 380 
VAL OXT HXT  sing N N 381 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1F8Y 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9F08 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006736 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006736 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006736 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0487   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . MET A 1 1   ? 5.794  -14.916 59.601 1.000 80.937  0 1   MET A N   1 ? 
ATOM   2    C CA  . MET A 1 1   ? 5.901  -15.542 58.250 1.000 93.136  0 1   MET A CA  1 ? 
ATOM   3    C C   . MET A 1 1   ? 7.353  -15.463 57.775 1.000 75.422  0 1   MET A C   1 ? 
ATOM   4    O O   . MET A 1 1   ? 7.851  -14.374 57.544 1.000 67.253  0 1   MET A O   1 ? 
ATOM   5    C CB  . MET A 1 1   ? 4.990  -14.816 57.245 1.000 104.299 0 1   MET A CB  1 ? 
ATOM   6    C CG  . MET A 1 1   ? 4.959  -15.397 55.822 1.000 102.051 0 1   MET A CG  1 ? 
ATOM   7    S SD  . MET A 1 1   ? 3.518  -16.405 55.402 1.000 102.084 0 1   MET A SD  1 ? 
ATOM   8    C CE  . MET A 1 1   ? 3.822  -17.924 56.317 1.000 110.479 0 1   MET A CE  1 ? 
ATOM   9    N N   . PRO A 1 2   ? 8.111  -16.581 57.692 1.000 66.865  0 2   PRO A N   1 ? 
ATOM   10   C CA  . PRO A 1 2   ? 9.437  -16.557 57.068 1.000 63.195  0 2   PRO A CA  1 ? 
ATOM   11   C C   . PRO A 1 2   ? 9.337  -16.230 55.575 1.000 57.226  0 2   PRO A C   1 ? 
ATOM   12   O O   . PRO A 1 2   ? 8.326  -16.525 54.939 1.000 56.245  0 2   PRO A O   1 ? 
ATOM   13   C CB  . PRO A 1 2   ? 10.022 -17.967 57.317 1.000 60.840  0 2   PRO A CB  1 ? 
ATOM   14   C CG  . PRO A 1 2   ? 9.133  -18.579 58.379 1.000 61.945  0 2   PRO A CG  1 ? 
ATOM   15   C CD  . PRO A 1 2   ? 7.767  -17.909 58.236 1.000 62.834  0 2   PRO A CD  1 ? 
ATOM   16   N N   . LYS A 1 3   ? 10.389 -15.611 55.031 1.000 57.850  0 3   LYS A N   1 ? 
ATOM   17   C CA  . LYS A 1 3   ? 10.414 -15.171 53.642 1.000 62.287  0 3   LYS A CA  1 ? 
ATOM   18   C C   . LYS A 1 3   ? 11.692 -15.680 52.968 1.000 63.391  0 3   LYS A C   1 ? 
ATOM   19   O O   . LYS A 1 3   ? 12.739 -15.733 53.591 1.000 54.656  0 3   LYS A O   1 ? 
ATOM   20   C CB  . LYS A 1 3   ? 10.336 -13.642 53.587 1.000 63.565  0 3   LYS A CB  1 ? 
ATOM   21   C CG  . LYS A 1 3   ? 8.986  -13.019 53.855 1.000 68.839  0 3   LYS A CG  1 ? 
ATOM   22   C CD  . LYS A 1 3   ? 9.088  -11.494 53.951 1.000 71.982  0 3   LYS A CD  1 ? 
ATOM   23   C CE  . LYS A 1 3   ? 7.799  -10.717 53.984 1.000 72.574  0 3   LYS A CE  1 ? 
ATOM   24   N NZ  . LYS A 1 3   ? 7.408  -10.359 52.618 1.000 83.811  0 3   LYS A NZ  1 ? 
ATOM   25   N N   . LYS A 1 4   ? 11.609 -16.040 51.679 1.000 59.693  0 4   LYS A N   1 ? 
ATOM   26   C CA  . LYS A 1 4   ? 12.747 -16.543 50.944 1.000 57.691  0 4   LYS A CA  1 ? 
ATOM   27   C C   . LYS A 1 4   ? 13.098 -15.544 49.841 1.000 55.163  0 4   LYS A C   1 ? 
ATOM   28   O O   . LYS A 1 4   ? 12.215 -14.891 49.308 1.000 61.218  0 4   LYS A O   1 ? 
ATOM   29   C CB  . LYS A 1 4   ? 12.458 -17.923 50.340 1.000 57.813  0 4   LYS A CB  1 ? 
ATOM   30   C CG  . LYS A 1 4   ? 12.002 -19.049 51.271 1.000 63.756  0 4   LYS A CG  1 ? 
ATOM   31   C CD  . LYS A 1 4   ? 12.909 -19.580 52.381 1.000 65.298  0 4   LYS A CD  1 ? 
ATOM   32   C CE  . LYS A 1 4   ? 13.448 -20.948 52.246 1.000 77.672  0 4   LYS A CE  1 ? 
ATOM   33   N NZ  . LYS A 1 4   ? 12.472 -22.033 52.075 1.000 82.616  0 4   LYS A NZ  1 ? 
ATOM   34   N N   . THR A 1 5   ? 14.381 -15.463 49.465 1.000 49.807  0 5   THR A N   1 ? 
ATOM   35   C CA  . THR A 1 5   ? 14.781 -14.665 48.317 1.000 48.994  0 5   THR A CA  1 ? 
ATOM   36   C C   . THR A 1 5   ? 14.863 -15.571 47.094 1.000 52.061  0 5   THR A C   1 ? 
ATOM   37   O O   . THR A 1 5   ? 15.003 -16.785 47.231 1.000 49.068  0 5   THR A O   1 ? 
ATOM   38   C CB  . THR A 1 5   ? 16.112 -13.965 48.581 1.000 53.354  0 5   THR A CB  1 ? 
ATOM   39   O OG1 . THR A 1 5   ? 17.074 -14.989 48.825 1.000 51.593  0 5   THR A OG1 1 ? 
ATOM   40   C CG2 . THR A 1 5   ? 16.039 -13.009 49.761 1.000 48.516  0 5   THR A CG2 1 ? 
ATOM   41   N N   . ILE A 1 6   ? 14.800 -14.955 45.913 1.000 51.333  0 6   ILE A N   1 ? 
ATOM   42   C CA  . ILE A 1 6   ? 14.829 -15.690 44.656 1.000 56.608  0 6   ILE A CA  1 ? 
ATOM   43   C C   . ILE A 1 6   ? 15.809 -15.043 43.681 1.000 52.819  0 6   ILE A C   1 ? 
ATOM   44   O O   . ILE A 1 6   ? 16.217 -13.896 43.849 1.000 53.805  0 6   ILE A O   1 ? 
ATOM   45   C CB  . ILE A 1 6   ? 13.440 -15.821 43.992 1.000 59.580  0 6   ILE A CB  1 ? 
ATOM   46   C CG1 . ILE A 1 6   ? 12.789 -14.487 43.719 1.000 58.538  0 6   ILE A CG1 1 ? 
ATOM   47   C CG2 . ILE A 1 6   ? 12.525 -16.727 44.793 1.000 66.831  0 6   ILE A CG2 1 ? 
ATOM   48   C CD1 . ILE A 1 6   ? 13.083 -13.938 42.336 1.000 60.556  0 6   ILE A CD1 1 ? 
ATOM   49   N N   . TYR A 1 7   ? 16.207 -15.853 42.684 1.000 51.516  0 7   TYR A N   1 ? 
ATOM   50   C CA  . TYR A 1 7   ? 16.871 -15.367 41.488 1.000 54.488  0 7   TYR A CA  1 ? 
ATOM   51   C C   . TYR A 1 7   ? 15.828 -15.372 40.385 1.000 51.245  0 7   TYR A C   1 ? 
ATOM   52   O O   . TYR A 1 7   ? 15.233 -16.423 40.137 1.000 49.938  0 7   TYR A O   1 ? 
ATOM   53   C CB  . TYR A 1 7   ? 18.066 -16.247 41.106 1.000 50.910  0 7   TYR A CB  1 ? 
ATOM   54   C CG  . TYR A 1 7   ? 18.743 -15.921 39.785 1.000 49.964  0 7   TYR A CG  1 ? 
ATOM   55   C CD1 . TYR A 1 7   ? 18.291 -16.472 38.596 1.000 51.573  0 7   TYR A CD1 1 ? 
ATOM   56   C CD2 . TYR A 1 7   ? 19.872 -15.109 39.725 1.000 51.405  0 7   TYR A CD2 1 ? 
ATOM   57   C CE1 . TYR A 1 7   ? 18.916 -16.191 37.392 1.000 57.637  0 7   TYR A CE1 1 ? 
ATOM   58   C CE2 . TYR A 1 7   ? 20.507 -14.828 38.521 1.000 55.622  0 7   TYR A CE2 1 ? 
ATOM   59   C CZ  . TYR A 1 7   ? 20.037 -15.384 37.351 1.000 54.565  0 7   TYR A CZ  1 ? 
ATOM   60   O OH  . TYR A 1 7   ? 20.664 -15.148 36.151 1.000 60.350  0 7   TYR A OH  1 ? 
ATOM   61   N N   . PHE A 1 8   ? 15.635 -14.187 39.763 1.000 51.551  0 8   PHE A N   1 ? 
ATOM   62   C CA  . PHE A 1 8   ? 14.594 -13.976 38.777 1.000 49.381  0 8   PHE A CA  1 ? 
ATOM   63   C C   . PHE A 1 8   ? 15.103 -14.430 37.419 1.000 53.713  0 8   PHE A C   1 ? 
ATOM   64   O O   . PHE A 1 8   ? 15.537 -13.603 36.621 1.000 53.904  0 8   PHE A O   1 ? 
ATOM   65   C CB  . PHE A 1 8   ? 14.127 -12.520 38.743 1.000 51.237  0 8   PHE A CB  1 ? 
ATOM   66   C CG  . PHE A 1 8   ? 12.827 -12.326 37.977 1.000 52.422  0 8   PHE A CG  1 ? 
ATOM   67   C CD1 . PHE A 1 8   ? 11.595 -12.557 38.591 1.000 53.080  0 8   PHE A CD1 1 ? 
ATOM   68   C CD2 . PHE A 1 8   ? 12.842 -11.945 36.638 1.000 56.403  0 8   PHE A CD2 1 ? 
ATOM   69   C CE1 . PHE A 1 8   ? 10.411 -12.405 37.885 1.000 58.077  0 8   PHE A CE1 1 ? 
ATOM   70   C CE2 . PHE A 1 8   ? 11.658 -11.784 35.933 1.000 59.302  0 8   PHE A CE2 1 ? 
ATOM   71   C CZ  . PHE A 1 8   ? 10.442 -12.020 36.558 1.000 57.843  0 8   PHE A CZ  1 ? 
ATOM   72   N N   . GLY A 1 9   ? 15.044 -15.745 37.164 1.000 49.690  0 9   GLY A N   1 ? 
ATOM   73   C CA  . GLY A 1 9   ? 15.416 -16.253 35.848 1.000 52.615  0 9   GLY A CA  1 ? 
ATOM   74   C C   . GLY A 1 9   ? 14.296 -16.064 34.822 1.000 56.326  0 9   GLY A C   1 ? 
ATOM   75   O O   . GLY A 1 9   ? 13.174 -16.558 35.011 1.000 56.926  0 9   GLY A O   1 ? 
ATOM   76   N N   . ALA A 1 10  ? 14.629 -15.359 33.734 1.000 55.794  0 10  ALA A N   1 ? 
ATOM   77   C CA  . ALA A 1 10  ? 13.685 -15.027 32.675 1.000 50.265  0 10  ALA A CA  1 ? 
ATOM   78   C C   . ALA A 1 10  ? 14.415 -14.447 31.477 1.000 58.993  0 10  ALA A C   1 ? 
ATOM   79   O O   . ALA A 1 10  ? 15.195 -13.521 31.651 1.000 52.201  0 10  ALA A O   1 ? 
ATOM   80   C CB  . ALA A 1 10  ? 12.723 -13.964 33.154 1.000 47.976  0 10  ALA A CB  1 ? 
ATOM   81   N N   . GLY A 1 11  ? 14.058 -14.901 30.269 1.000 57.973  0 11  GLY A N   1 ? 
ATOM   82   C CA  . GLY A 1 11  ? 14.440 -14.181 29.066 1.000 56.507  0 11  GLY A CA  1 ? 
ATOM   83   C C   . GLY A 1 11  ? 13.762 -12.814 28.989 1.000 52.960  0 11  GLY A C   1 ? 
ATOM   84   O O   . GLY A 1 11  ? 12.712 -12.594 29.591 1.000 59.686  0 11  GLY A O   1 ? 
ATOM   85   N N   . TRP A 1 12  ? 14.352 -11.908 28.197 1.000 55.459  0 12  TRP A N   1 ? 
ATOM   86   C CA  . TRP A 1 12  ? 13.789 -10.585 27.985 1.000 55.506  0 12  TRP A CA  1 ? 
ATOM   87   C C   . TRP A 1 12  ? 13.929 -10.163 26.525 1.000 59.187  0 12  TRP A C   1 ? 
ATOM   88   O O   . TRP A 1 12  ? 14.042 -8.969  26.262 1.000 60.278  0 12  TRP A O   1 ? 
ATOM   89   C CB  . TRP A 1 12  ? 14.429 -9.565  28.930 1.000 55.094  0 12  TRP A CB  1 ? 
ATOM   90   C CG  . TRP A 1 12  ? 15.920 -9.402  28.802 1.000 66.986  0 12  TRP A CG  1 ? 
ATOM   91   C CD1 . TRP A 1 12  ? 16.602 -8.694  27.850 1.000 64.880  0 12  TRP A CD1 1 ? 
ATOM   92   C CD2 . TRP A 1 12  ? 16.916 -9.895  29.726 1.000 58.017  0 12  TRP A CD2 1 ? 
ATOM   93   N NE1 . TRP A 1 12  ? 17.947 -8.759  28.089 1.000 62.606  0 12  TRP A NE1 1 ? 
ATOM   94   C CE2 . TRP A 1 12  ? 18.171 -9.469  29.241 1.000 64.302  0 12  TRP A CE2 1 ? 
ATOM   95   C CE3 . TRP A 1 12  ? 16.865 -10.648 30.906 1.000 53.659  0 12  TRP A CE3 1 ? 
ATOM   96   C CZ2 . TRP A 1 12  ? 19.369 -9.793  29.889 1.000 65.927  0 12  TRP A CZ2 1 ? 
ATOM   97   C CZ3 . TRP A 1 12  ? 18.039 -10.938 31.567 1.000 64.508  0 12  TRP A CZ3 1 ? 
ATOM   98   C CH2 . TRP A 1 12  ? 19.283 -10.530 31.054 1.000 65.042  0 12  TRP A CH2 1 ? 
ATOM   99   N N   . PHE A 1 13  ? 13.845 -11.146 25.601 1.000 60.644  0 13  PHE A N   1 ? 
ATOM   100  C CA  . PHE A 1 13  ? 14.276 -10.976 24.213 1.000 66.094  0 13  PHE A CA  1 ? 
ATOM   101  C C   . PHE A 1 13  ? 13.139 -11.105 23.194 1.000 66.552  0 13  PHE A C   1 ? 
ATOM   102  O O   . PHE A 1 13  ? 13.417 -11.049 22.003 1.000 71.631  0 13  PHE A O   1 ? 
ATOM   103  C CB  . PHE A 1 13  ? 15.300 -12.052 23.840 1.000 55.857  0 13  PHE A CB  1 ? 
ATOM   104  C CG  . PHE A 1 13  ? 16.453 -12.113 24.825 1.000 64.488  0 13  PHE A CG  1 ? 
ATOM   105  C CD1 . PHE A 1 13  ? 17.343 -11.039 24.933 1.000 68.064  0 13  PHE A CD1 1 ? 
ATOM   106  C CD2 . PHE A 1 13  ? 16.647 -13.234 25.631 1.000 60.653  0 13  PHE A CD2 1 ? 
ATOM   107  C CE1 . PHE A 1 13  ? 18.370 -11.069 25.858 1.000 64.506  0 13  PHE A CE1 1 ? 
ATOM   108  C CE2 . PHE A 1 13  ? 17.690 -13.262 26.545 1.000 61.577  0 13  PHE A CE2 1 ? 
ATOM   109  C CZ  . PHE A 1 13  ? 18.539 -12.184 26.666 1.000 64.156  0 13  PHE A CZ  1 ? 
ATOM   110  N N   . THR A 1 14  ? 11.900 -11.343 23.648 1.000 71.770  0 14  THR A N   1 ? 
ATOM   111  C CA  . THR A 1 14  ? 10.723 -11.429 22.786 1.000 71.301  0 14  THR A CA  1 ? 
ATOM   112  C C   . THR A 1 14  ? 9.547  -10.783 23.517 1.000 69.322  0 14  THR A C   1 ? 
ATOM   113  O O   . THR A 1 14  ? 9.677  -10.391 24.675 1.000 69.972  0 14  THR A O   1 ? 
ATOM   114  C CB  . THR A 1 14  ? 10.365 -12.874 22.416 1.000 66.346  0 14  THR A CB  1 ? 
ATOM   115  O OG1 . THR A 1 14  ? 9.822  -13.434 23.600 1.000 67.294  0 14  THR A OG1 1 ? 
ATOM   116  C CG2 . THR A 1 14  ? 11.527 -13.744 21.989 1.000 67.042  0 14  THR A CG2 1 ? 
ATOM   117  N N   . ASP A 1 15  ? 8.397  -10.688 22.837 1.000 74.036  0 15  ASP A N   1 ? 
ATOM   118  C CA  . ASP A 1 15  ? 7.211  -10.057 23.399 1.000 64.876  0 15  ASP A CA  1 ? 
ATOM   119  C C   . ASP A 1 15  ? 6.557  -10.983 24.414 1.000 63.542  0 15  ASP A C   1 ? 
ATOM   120  O O   . ASP A 1 15  ? 6.117  -10.531 25.472 1.000 59.189  0 15  ASP A O   1 ? 
ATOM   121  C CB  . ASP A 1 15  ? 6.214  -9.671  22.320 1.000 74.440  0 15  ASP A CB  1 ? 
ATOM   122  C CG  . ASP A 1 15  ? 6.684  -8.542  21.409 1.000 81.364  0 15  ASP A CG  1 ? 
ATOM   123  O OD1 . ASP A 1 15  ? 7.542  -7.741  21.844 1.000 77.214  0 15  ASP A OD1 1 ? 
ATOM   124  O OD2 . ASP A 1 15  ? 6.221  -8.498  20.257 1.000 81.887  0 15  ASP A OD2 1 ? 
ATOM   125  N N   . ARG A 1 16  ? 6.479  -12.277 24.081 1.000 55.628  0 16  ARG A N   1 ? 
ATOM   126  C CA  . ARG A 1 16  ? 5.918  -13.231 25.023 1.000 63.645  0 16  ARG A CA  1 ? 
ATOM   127  C C   . ARG A 1 16  ? 6.783  -13.280 26.279 1.000 57.117  0 16  ARG A C   1 ? 
ATOM   128  O O   . ARG A 1 16  ? 6.235  -13.241 27.376 1.000 67.907  0 16  ARG A O   1 ? 
ATOM   129  C CB  . ARG A 1 16  ? 5.660  -14.561 24.321 1.000 62.048  0 16  ARG A CB  1 ? 
ATOM   130  C CG  . ARG A 1 16  ? 4.612  -14.384 23.230 1.000 64.875  0 16  ARG A CG  1 ? 
ATOM   131  C CD  . ARG A 1 16  ? 4.646  -15.563 22.253 1.000 68.250  0 16  ARG A CD  1 ? 
ATOM   132  N NE  . ARG A 1 16  ? 4.173  -16.722 23.004 1.000 57.833  0 16  ARG A NE  1 ? 
ATOM   133  C CZ  . ARG A 1 16  ? 4.298  -17.972 22.632 1.000 71.378  0 16  ARG A CZ  1 ? 
ATOM   134  N NH1 . ARG A 1 16  ? 4.759  -18.237 21.422 1.000 75.737  0 16  ARG A NH1 1 ? 
ATOM   135  N NH2 . ARG A 1 16  ? 3.939  -18.932 23.480 1.000 69.356  0 16  ARG A NH2 1 ? 
ATOM   136  N N   . GLN A 1 17  ? 8.117  -13.226 26.112 1.000 64.494  0 17  GLN A N   1 ? 
ATOM   137  C CA  . GLN A 1 17  ? 9.056  -13.284 27.226 1.000 56.000  0 17  GLN A CA  1 ? 
ATOM   138  C C   . GLN A 1 17  ? 8.823  -12.083 28.136 1.000 62.457  0 17  GLN A C   1 ? 
ATOM   139  O O   . GLN A 1 17  ? 8.778  -12.224 29.357 1.000 55.558  0 17  GLN A O   1 ? 
ATOM   140  C CB  . GLN A 1 17  ? 10.528 -13.353 26.796 1.000 55.595  0 17  GLN A CB  1 ? 
ATOM   141  C CG  . GLN A 1 17  ? 10.946 -14.737 26.319 1.000 54.890  0 17  GLN A CG  1 ? 
ATOM   142  C CD  . GLN A 1 17  ? 12.377 -14.842 25.830 1.000 58.421  0 17  GLN A CD  1 ? 
ATOM   143  O OE1 . GLN A 1 17  ? 13.179 -13.906 25.923 1.000 60.848  0 17  GLN A OE1 1 ? 
ATOM   144  N NE2 . GLN A 1 17  ? 12.715 -16.027 25.334 1.000 56.101  0 17  GLN A NE2 1 ? 
ATOM   145  N N   . ASN A 1 18  ? 8.660  -10.908 27.531 1.000 63.047  0 18  ASN A N   1 ? 
ATOM   146  C CA  . ASN A 1 18  ? 8.526  -9.678  28.288 1.000 64.438  0 18  ASN A CA  1 ? 
ATOM   147  C C   . ASN A 1 18  ? 7.175  -9.648  29.002 1.000 63.138  0 18  ASN A C   1 ? 
ATOM   148  O O   . ASN A 1 18  ? 7.066  -9.136  30.115 1.000 62.095  0 18  ASN A O   1 ? 
ATOM   149  C CB  . ASN A 1 18  ? 8.758  -8.453  27.406 1.000 62.945  0 18  ASN A CB  1 ? 
ATOM   150  C CG  . ASN A 1 18  ? 10.222 -8.229  27.133 1.000 66.795  0 18  ASN A CG  1 ? 
ATOM   151  O OD1 . ASN A 1 18  ? 11.045 -8.332  28.041 1.000 64.712  0 18  ASN A OD1 1 ? 
ATOM   152  N ND2 . ASN A 1 18  ? 10.569 -7.931  25.896 1.000 67.912  0 18  ASN A ND2 1 ? 
ATOM   153  N N   . LYS A 1 19  ? 6.140  -10.187 28.359 1.000 68.197  0 19  LYS A N   1 ? 
ATOM   154  C CA  . LYS A 1 19  ? 4.828  -10.199 28.978 1.000 66.050  0 19  LYS A CA  1 ? 
ATOM   155  C C   . LYS A 1 19  ? 4.891  -11.070 30.240 1.000 61.287  0 19  LYS A C   1 ? 
ATOM   156  O O   . LYS A 1 19  ? 4.485  -10.638 31.320 1.000 66.772  0 19  LYS A O   1 ? 
ATOM   157  C CB  . LYS A 1 19  ? 3.765  -10.677 27.982 1.000 68.996  0 19  LYS A CB  1 ? 
ATOM   158  C CG  . LYS A 1 19  ? 2.328  -10.544 28.506 1.000 75.241  0 19  LYS A CG  1 ? 
ATOM   159  C CD  . LYS A 1 19  ? 1.245  -11.088 27.582 1.000 83.863  0 19  LYS A CD  1 ? 
ATOM   160  C CE  . LYS A 1 19  ? -0.117 -10.830 28.167 1.000 87.822  0 19  LYS A CE  1 ? 
ATOM   161  N NZ  . LYS A 1 19  ? -1.117 -11.742 27.603 1.000 90.587  0 19  LYS A NZ  1 ? 
ATOM   162  N N   . ALA A 1 20  ? 5.405  -12.298 30.078 1.000 60.802  0 20  ALA A N   1 ? 
ATOM   163  C CA  . ALA A 1 20  ? 5.531  -13.253 31.165 1.000 55.362  0 20  ALA A CA  1 ? 
ATOM   164  C C   . ALA A 1 20  ? 6.426  -12.705 32.284 1.000 54.203  0 20  ALA A C   1 ? 
ATOM   165  O O   . ALA A 1 20  ? 6.121  -12.845 33.467 1.000 53.731  0 20  ALA A O   1 ? 
ATOM   166  C CB  . ALA A 1 20  ? 6.063  -14.533 30.600 1.000 64.059  0 20  ALA A CB  1 ? 
ATOM   167  N N   . TYR A 1 21  ? 7.515  -12.044 31.901 1.000 53.306  0 21  TYR A N   1 ? 
ATOM   168  C CA  . TYR A 1 21  ? 8.402  -11.387 32.843 1.000 53.665  0 21  TYR A CA  1 ? 
ATOM   169  C C   . TYR A 1 21  ? 7.602  -10.445 33.747 1.000 56.404  0 21  TYR A C   1 ? 
ATOM   170  O O   . TYR A 1 21  ? 7.715  -10.513 34.977 1.000 58.177  0 21  TYR A O   1 ? 
ATOM   171  C CB  . TYR A 1 21  ? 9.487  -10.711 31.992 1.000 52.050  0 21  TYR A CB  1 ? 
ATOM   172  C CG  . TYR A 1 21  ? 10.578 -9.998  32.770 1.000 60.519  0 21  TYR A CG  1 ? 
ATOM   173  C CD1 . TYR A 1 21  ? 10.288 -8.939  33.632 1.000 54.489  0 21  TYR A CD1 1 ? 
ATOM   174  C CD2 . TYR A 1 21  ? 11.912 -10.362 32.617 1.000 58.136  0 21  TYR A CD2 1 ? 
ATOM   175  C CE1 . TYR A 1 21  ? 11.284 -8.304  34.358 1.000 56.276  0 21  TYR A CE1 1 ? 
ATOM   176  C CE2 . TYR A 1 21  ? 12.919 -9.729  33.334 1.000 57.293  0 21  TYR A CE2 1 ? 
ATOM   177  C CZ  . TYR A 1 21  ? 12.603 -8.696  34.198 1.000 60.345  0 21  TYR A CZ  1 ? 
ATOM   178  O OH  . TYR A 1 21  ? 13.603 -8.069  34.870 1.000 56.257  0 21  TYR A OH  1 ? 
ATOM   179  N N   . LYS A 1 22  ? 6.808  -9.552  33.132 1.000 63.447  0 22  LYS A N   1 ? 
ATOM   180  C CA  . LYS A 1 22  ? 6.084  -8.521  33.867 1.000 64.309  0 22  LYS A CA  1 ? 
ATOM   181  C C   . LYS A 1 22  ? 5.077  -9.168  34.808 1.000 62.765  0 22  LYS A C   1 ? 
ATOM   182  O O   . LYS A 1 22  ? 4.963  -8.755  35.971 1.000 59.438  0 22  LYS A O   1 ? 
ATOM   183  C CB  . LYS A 1 22  ? 5.388  -7.496  32.963 1.000 75.039  0 22  LYS A CB  1 ? 
ATOM   184  C CG  . LYS A 1 22  ? 6.319  -6.458  32.381 1.000 94.665  0 22  LYS A CG  1 ? 
ATOM   185  C CD  . LYS A 1 22  ? 5.778  -5.692  31.181 1.000 100.340 0 22  LYS A CD  1 ? 
ATOM   186  C CE  . LYS A 1 22  ? 6.929  -5.399  30.271 1.000 104.075 0 22  LYS A CE  1 ? 
ATOM   187  N NZ  . LYS A 1 22  ? 6.556  -4.460  29.221 1.000 115.320 0 22  LYS A NZ  1 ? 
ATOM   188  N N   . GLU A 1 23  ? 4.375  -10.192 34.292 1.000 58.300  0 23  GLU A N   1 ? 
ATOM   189  C CA  . GLU A 1 23  ? 3.365  -10.917 35.050 1.000 58.236  0 23  GLU A CA  1 ? 
ATOM   190  C C   . GLU A 1 23  ? 3.998  -11.581 36.272 1.000 64.957  0 23  GLU A C   1 ? 
ATOM   191  O O   . GLU A 1 23  ? 3.459  -11.531 37.379 1.000 64.682  0 23  GLU A O   1 ? 
ATOM   192  C CB  . GLU A 1 23  ? 2.673  -11.949 34.166 1.000 59.070  0 23  GLU A CB  1 ? 
ATOM   193  C CG  . GLU A 1 23  ? 1.626  -11.358 33.216 1.000 63.859  0 23  GLU A CG  1 ? 
ATOM   194  C CD  . GLU A 1 23  ? 0.913  -12.347 32.269 1.000 65.735  0 23  GLU A CD  1 ? 
ATOM   195  O OE1 . GLU A 1 23  ? -0.070 -11.902 31.633 1.000 72.374  0 23  GLU A OE1 1 ? 
ATOM   196  O OE2 . GLU A 1 23  ? 1.328  -13.531 32.102 1.000 58.827  0 23  GLU A OE2 1 ? 
ATOM   197  N N   . ALA A 1 24  ? 5.179  -12.178 36.067 1.000 65.039  0 24  ALA A N   1 ? 
ATOM   198  C CA  . ALA A 1 24  ? 5.834  -12.922 37.127 1.000 60.442  0 24  ALA A CA  1 ? 
ATOM   199  C C   . ALA A 1 24  ? 6.310  -11.985 38.232 1.000 58.415  0 24  ALA A C   1 ? 
ATOM   200  O O   . ALA A 1 24  ? 6.263  -12.325 39.418 1.000 61.897  0 24  ALA A O   1 ? 
ATOM   201  C CB  . ALA A 1 24  ? 6.967  -13.742 36.562 1.000 65.205  0 24  ALA A CB  1 ? 
ATOM   202  N N   . MET A 1 25  ? 6.763  -10.795 37.836 1.000 55.080  0 25  MET A N   1 ? 
ATOM   203  C CA  . MET A 1 25  ? 7.243  -9.826  38.797 1.000 55.591  0 25  MET A CA  1 ? 
ATOM   204  C C   . MET A 1 25  ? 6.068  -9.377  39.665 1.000 63.878  0 25  MET A C   1 ? 
ATOM   205  O O   . MET A 1 25  ? 6.204  -9.293  40.885 1.000 64.069  0 25  MET A O   1 ? 
ATOM   206  C CB  . MET A 1 25  ? 7.928  -8.651  38.087 1.000 50.401  0 25  MET A CB  1 ? 
ATOM   207  C CG  . MET A 1 25  ? 8.831  -7.829  38.988 1.000 61.501  0 25  MET A CG  1 ? 
ATOM   208  S SD  . MET A 1 25  ? 10.256 -8.710  39.675 1.000 63.958  0 25  MET A SD  1 ? 
ATOM   209  C CE  . MET A 1 25  ? 11.225 -8.732  38.161 1.000 61.516  0 25  MET A CE  1 ? 
ATOM   210  N N   . GLU A 1 26  ? 4.912  -9.099  39.045 1.000 69.322  0 26  GLU A N   1 ? 
ATOM   211  C CA  . GLU A 1 26  ? 3.749  -8.625  39.792 1.000 68.924  0 26  GLU A CA  1 ? 
ATOM   212  C C   . GLU A 1 26  ? 3.262  -9.710  40.750 1.000 65.388  0 26  GLU A C   1 ? 
ATOM   213  O O   . GLU A 1 26  ? 2.914  -9.426  41.900 1.000 65.404  0 26  GLU A O   1 ? 
ATOM   214  C CB  . GLU A 1 26  ? 2.587  -8.190  38.899 1.000 71.398  0 26  GLU A CB  1 ? 
ATOM   215  C CG  . GLU A 1 26  ? 2.690  -6.734  38.450 1.000 80.828  0 26  GLU A CG  1 ? 
ATOM   216  C CD  . GLU A 1 26  ? 1.941  -6.456  37.147 1.000 101.613 0 26  GLU A CD  1 ? 
ATOM   217  O OE1 . GLU A 1 26  ? 1.416  -7.402  36.504 1.000 100.204 0 26  GLU A OE1 1 ? 
ATOM   218  O OE2 . GLU A 1 26  ? 1.879  -5.268  36.761 1.000 108.939 0 26  GLU A OE2 1 ? 
ATOM   219  N N   . ALA A 1 27  ? 3.246  -10.957 40.261 1.000 61.168  0 27  ALA A N   1 ? 
ATOM   220  C CA  . ALA A 1 27  ? 2.888  -12.076 41.102 1.000 53.690  0 27  ALA A CA  1 ? 
ATOM   221  C C   . ALA A 1 27  ? 3.789  -12.144 42.341 1.000 64.927  0 27  ALA A C   1 ? 
ATOM   222  O O   . ALA A 1 27  ? 3.298  -12.338 43.461 1.000 55.655  0 27  ALA A O   1 ? 
ATOM   223  C CB  . ALA A 1 27  ? 2.938  -13.323 40.284 1.000 53.844  0 27  ALA A CB  1 ? 
ATOM   224  N N   . LEU A 1 28  ? 5.100  -11.914 42.157 1.000 61.300  0 28  LEU A N   1 ? 
ATOM   225  C CA  . LEU A 1 28  ? 6.053  -12.032 43.256 1.000 58.323  0 28  LEU A CA  1 ? 
ATOM   226  C C   . LEU A 1 28  ? 5.826  -10.973 44.331 1.000 55.807  0 28  LEU A C   1 ? 
ATOM   227  O O   . LEU A 1 28  ? 5.986  -11.256 45.526 1.000 59.249  0 28  LEU A O   1 ? 
ATOM   228  C CB  . LEU A 1 28  ? 7.494  -11.997 42.746 1.000 59.503  0 28  LEU A CB  1 ? 
ATOM   229  C CG  . LEU A 1 28  ? 7.968  -13.280 42.058 1.000 56.158  0 28  LEU A CG  1 ? 
ATOM   230  C CD1 . LEU A 1 28  ? 9.327  -13.011 41.500 1.000 62.129  0 28  LEU A CD1 1 ? 
ATOM   231  C CD2 . LEU A 1 28  ? 8.002  -14.482 42.992 1.000 58.263  0 28  LEU A CD2 1 ? 
ATOM   232  N N   . LYS A 1 29  ? 5.472  -9.757  43.918 1.000 56.006  0 29  LYS A N   1 ? 
ATOM   233  C CA  . LYS A 1 29  ? 5.248  -8.669  44.862 1.000 61.202  0 29  LYS A CA  1 ? 
ATOM   234  C C   . LYS A 1 29  ? 4.086  -8.980  45.812 1.000 60.617  0 29  LYS A C   1 ? 
ATOM   235  O O   . LYS A 1 29  ? 4.053  -8.462  46.918 1.000 63.841  0 29  LYS A O   1 ? 
ATOM   236  C CB  . LYS A 1 29  ? 4.912  -7.365  44.129 1.000 63.370  0 29  LYS A CB  1 ? 
ATOM   237  C CG  . LYS A 1 29  ? 6.038  -6.749  43.326 1.000 72.697  0 29  LYS A CG  1 ? 
ATOM   238  C CD  . LYS A 1 29  ? 5.663  -5.596  42.407 1.000 70.139  0 29  LYS A CD  1 ? 
ATOM   239  C CE  . LYS A 1 29  ? 6.886  -5.065  41.721 1.000 77.558  0 29  LYS A CE  1 ? 
ATOM   240  N NZ  . LYS A 1 29  ? 6.588  -4.475  40.414 1.000 77.320  0 29  LYS A NZ  1 ? 
ATOM   241  N N   . GLU A 1 30  ? 3.137  -9.822  45.373 1.000 64.555  0 30  GLU A N   1 ? 
ATOM   242  C CA  . GLU A 1 30  ? 1.958  -10.145 46.169 1.000 70.268  0 30  GLU A CA  1 ? 
ATOM   243  C C   . GLU A 1 30  ? 2.135  -11.436 46.961 1.000 66.445  0 30  GLU A C   1 ? 
ATOM   244  O O   . GLU A 1 30  ? 1.252  -11.794 47.737 1.000 67.698  0 30  GLU A O   1 ? 
ATOM   245  C CB  . GLU A 1 30  ? 0.699  -10.231 45.304 1.000 73.659  0 30  GLU A CB  1 ? 
ATOM   246  C CG  . GLU A 1 30  ? 0.524  -9.023  44.390 1.000 91.057  0 30  GLU A CG  1 ? 
ATOM   247  C CD  . GLU A 1 30  ? -0.853 -8.426  44.404 1.000 103.638 0 30  GLU A CD  1 ? 
ATOM   248  O OE1 . GLU A 1 30  ? -1.108 -7.616  45.322 1.000 107.264 0 30  GLU A OE1 1 ? 
ATOM   249  O OE2 . GLU A 1 30  ? -1.643 -8.802  43.515 1.000 112.101 0 30  GLU A OE2 1 ? 
ATOM   250  N N   . ASN A 1 31  ? 3.272  -12.128 46.786 1.000 59.222  0 31  ASN A N   1 ? 
ATOM   251  C CA  . ASN A 1 31  ? 3.489  -13.391 47.466 1.000 56.300  0 31  ASN A CA  1 ? 
ATOM   252  C C   . ASN A 1 31  ? 4.086  -13.137 48.848 1.000 60.079  0 31  ASN A C   1 ? 
ATOM   253  O O   . ASN A 1 31  ? 5.200  -12.675 48.953 1.000 58.014  0 31  ASN A O   1 ? 
ATOM   254  C CB  . ASN A 1 31  ? 4.400  -14.312 46.674 1.000 53.843  0 31  ASN A CB  1 ? 
ATOM   255  C CG  . ASN A 1 31  ? 4.430  -15.695 47.269 1.000 58.408  0 31  ASN A CG  1 ? 
ATOM   256  O OD1 . ASN A 1 31  ? 4.741  -15.855 48.452 1.000 67.031  0 31  ASN A OD1 1 ? 
ATOM   257  N ND2 . ASN A 1 31  ? 4.142  -16.711 46.472 1.000 63.483  0 31  ASN A ND2 1 ? 
ATOM   258  N N   . PRO A 1 32  ? 3.404  -13.470 49.962 1.000 66.381  0 32  PRO A N   1 ? 
ATOM   259  C CA  . PRO A 1 32  ? 3.939  -13.124 51.280 1.000 60.662  0 32  PRO A CA  1 ? 
ATOM   260  C C   . PRO A 1 32  ? 5.098  -13.993 51.773 1.000 56.294  0 32  PRO A C   1 ? 
ATOM   261  O O   . PRO A 1 32  ? 5.626  -13.720 52.841 1.000 59.089  0 32  PRO A O   1 ? 
ATOM   262  C CB  . PRO A 1 32  ? 2.674  -13.253 52.178 1.000 61.902  0 32  PRO A CB  1 ? 
ATOM   263  C CG  . PRO A 1 32  ? 1.872  -14.379 51.523 1.000 64.099  0 32  PRO A CG  1 ? 
ATOM   264  C CD  . PRO A 1 32  ? 2.095  -14.165 50.016 1.000 66.080  0 32  PRO A CD  1 ? 
ATOM   265  N N   . THR A 1 33  ? 5.505  -15.032 51.020 1.000 62.122  0 33  THR A N   1 ? 
ATOM   266  C CA  . THR A 1 33  ? 6.672  -15.832 51.399 1.000 64.021  0 33  THR A CA  1 ? 
ATOM   267  C C   . THR A 1 33  ? 7.932  -15.371 50.653 1.000 57.307  0 33  THR A C   1 ? 
ATOM   268  O O   . THR A 1 33  ? 8.980  -15.970 50.816 1.000 57.167  0 33  THR A O   1 ? 
ATOM   269  C CB  . THR A 1 33  ? 6.432  -17.334 51.211 1.000 66.322  0 33  THR A CB  1 ? 
ATOM   270  O OG1 . THR A 1 33  ? 6.214  -17.598 49.830 1.000 58.351  0 33  THR A OG1 1 ? 
ATOM   271  C CG2 . THR A 1 33  ? 5.254  -17.838 52.030 1.000 70.548  0 33  THR A CG2 1 ? 
ATOM   272  N N   . ILE A 1 34  ? 7.855  -14.276 49.891 1.000 55.519  0 34  ILE A N   1 ? 
ATOM   273  C CA  . ILE A 1 34  ? 8.964  -13.804 49.082 1.000 58.944  0 34  ILE A CA  1 ? 
ATOM   274  C C   . ILE A 1 34  ? 9.438  -12.445 49.586 1.000 57.731  0 34  ILE A C   1 ? 
ATOM   275  O O   . ILE A 1 34  ? 8.653  -11.527 49.779 1.000 54.728  0 34  ILE A O   1 ? 
ATOM   276  C CB  . ILE A 1 34  ? 8.528  -13.712 47.614 1.000 59.937  0 34  ILE A CB  1 ? 
ATOM   277  C CG1 . ILE A 1 34  ? 8.439  -15.089 46.960 1.000 67.212  0 34  ILE A CG1 1 ? 
ATOM   278  C CG2 . ILE A 1 34  ? 9.441  -12.777 46.835 1.000 65.062  0 34  ILE A CG2 1 ? 
ATOM   279  C CD1 . ILE A 1 34  ? 9.727  -15.889 46.994 1.000 74.108  0 34  ILE A CD1 1 ? 
ATOM   280  N N   . ASP A 1 35  ? 10.746 -12.340 49.809 1.000 52.895  0 35  ASP A N   1 ? 
ATOM   281  C CA  . ASP A 1 35  ? 11.394 -11.067 50.028 1.000 52.973  0 35  ASP A CA  1 ? 
ATOM   282  C C   . ASP A 1 35  ? 11.962 -10.629 48.690 1.000 54.904  0 35  ASP A C   1 ? 
ATOM   283  O O   . ASP A 1 35  ? 13.112 -10.944 48.364 1.000 58.830  0 35  ASP A O   1 ? 
ATOM   284  C CB  . ASP A 1 35  ? 12.391 -11.153 51.176 1.000 58.527  0 35  ASP A CB  1 ? 
ATOM   285  C CG  . ASP A 1 35  ? 13.260 -9.914  51.378 1.000 62.668  0 35  ASP A CG  1 ? 
ATOM   286  O OD1 . ASP A 1 35  ? 13.163 -8.987  50.550 1.000 61.284  0 35  ASP A OD1 1 ? 
ATOM   287  O OD2 . ASP A 1 35  ? 14.048 -9.887  52.351 1.000 65.986  0 35  ASP A OD2 1 ? 
ATOM   288  N N   . LEU A 1 36  ? 11.136 -9.894  47.933 1.000 54.378  0 36  LEU A N   1 ? 
ATOM   289  C CA  . LEU A 1 36  ? 11.509 -9.449  46.601 1.000 57.113  0 36  LEU A CA  1 ? 
ATOM   290  C C   . LEU A 1 36  ? 12.588 -8.377  46.636 1.000 54.594  0 36  LEU A C   1 ? 
ATOM   291  O O   . LEU A 1 36  ? 13.361 -8.243  45.699 1.000 54.525  0 36  LEU A O   1 ? 
ATOM   292  C CB  . LEU A 1 36  ? 10.305 -8.945  45.821 1.000 57.698  0 36  LEU A CB  1 ? 
ATOM   293  C CG  . LEU A 1 36  ? 10.577 -8.600  44.348 1.000 57.661  0 36  LEU A CG  1 ? 
ATOM   294  C CD1 . LEU A 1 36  ? 11.182 -9.806  43.631 1.000 54.829  0 36  LEU A CD1 1 ? 
ATOM   295  C CD2 . LEU A 1 36  ? 9.291  -8.145  43.647 1.000 62.919  0 36  LEU A CD2 1 ? 
ATOM   296  N N   . GLU A 1 37  ? 12.637 -7.594  47.699 1.000 55.605  0 37  GLU A N   1 ? 
ATOM   297  C CA  . GLU A 1 37  ? 13.550 -6.469  47.718 1.000 62.428  0 37  GLU A CA  1 ? 
ATOM   298  C C   . GLU A 1 37  ? 14.992 -6.956  47.897 1.000 61.704  0 37  GLU A C   1 ? 
ATOM   299  O O   . GLU A 1 37  ? 15.905 -6.245  47.524 1.000 53.002  0 37  GLU A O   1 ? 
ATOM   300  C CB  . GLU A 1 37  ? 13.207 -5.477  48.828 1.000 70.022  0 37  GLU A CB  1 ? 
ATOM   301  C CG  . GLU A 1 37  ? 13.362 -4.036  48.348 1.000 98.404  0 37  GLU A CG  1 ? 
ATOM   302  C CD  . GLU A 1 37  ? 14.036 -3.143  49.361 1.000 112.623 0 37  GLU A CD  1 ? 
ATOM   303  O OE1 . GLU A 1 37  ? 13.551 -3.114  50.520 1.000 114.025 0 37  GLU A OE1 1 ? 
ATOM   304  O OE2 . GLU A 1 37  ? 15.044 -2.497  48.974 1.000 99.687  0 37  GLU A OE2 1 ? 
ATOM   305  N N   . ASN A 1 38  ? 15.196 -8.140  48.506 1.000 54.358  0 38  ASN A N   1 ? 
ATOM   306  C CA  . ASN A 1 38  ? 16.532 -8.677  48.721 1.000 55.214  0 38  ASN A CA  1 ? 
ATOM   307  C C   . ASN A 1 38  ? 16.861 -9.750  47.682 1.000 48.709  0 38  ASN A C   1 ? 
ATOM   308  O O   . ASN A 1 38  ? 17.880 -10.433 47.783 1.000 62.111  0 38  ASN A O   1 ? 
ATOM   309  C CB  . ASN A 1 38  ? 16.701 -9.114  50.171 1.000 53.711  0 38  ASN A CB  1 ? 
ATOM   310  C CG  . ASN A 1 38  ? 16.687 -7.923  51.112 1.000 53.727  0 38  ASN A CG  1 ? 
ATOM   311  O OD1 . ASN A 1 38  ? 15.989 -7.944  52.121 1.000 58.970  0 38  ASN A OD1 1 ? 
ATOM   312  N ND2 . ASN A 1 38  ? 17.467 -6.885  50.837 1.000 49.092  0 38  ASN A ND2 1 ? 
ATOM   313  N N   . SER A 1 39  ? 15.991 -9.866  46.669 1.000 55.842  0 39  SER A N   1 ? 
ATOM   314  C CA  . SER A 1 39  ? 16.114 -10.878 45.643 1.000 49.682  0 39  SER A CA  1 ? 
ATOM   315  C C   . SER A 1 39  ? 17.018 -10.335 44.558 1.000 52.658  0 39  SER A C   1 ? 
ATOM   316  O O   . SER A 1 39  ? 17.318 -9.145  44.555 1.000 52.604  0 39  SER A O   1 ? 
ATOM   317  C CB  . SER A 1 39  ? 14.767 -11.278 45.104 1.000 54.592  0 39  SER A CB  1 ? 
ATOM   318  O OG  . SER A 1 39  ? 14.056 -12.053 46.059 1.000 49.066  0 39  SER A OG  1 ? 
ATOM   319  N N   . TYR A 1 40  ? 17.440 -11.218 43.646 1.000 49.931  0 40  TYR A N   1 ? 
ATOM   320  C CA  . TYR A 1 40  ? 18.337 -10.812 42.581 1.000 45.967  0 40  TYR A CA  1 ? 
ATOM   321  C C   . TYR A 1 40  ? 17.596 -10.854 41.250 1.000 46.283  0 40  TYR A C   1 ? 
ATOM   322  O O   . TYR A 1 40  ? 17.128 -11.911 40.823 1.000 50.122  0 40  TYR A O   1 ? 
ATOM   323  C CB  . TYR A 1 40  ? 19.589 -11.690 42.533 1.000 47.676  0 40  TYR A CB  1 ? 
ATOM   324  C CG  . TYR A 1 40  ? 20.606 -11.283 41.468 1.000 50.413  0 40  TYR A CG  1 ? 
ATOM   325  C CD1 . TYR A 1 40  ? 20.478 -11.734 40.165 1.000 46.933  0 40  TYR A CD1 1 ? 
ATOM   326  C CD2 . TYR A 1 40  ? 21.727 -10.529 41.788 1.000 48.579  0 40  TYR A CD2 1 ? 
ATOM   327  C CE1 . TYR A 1 40  ? 21.397 -11.383 39.198 1.000 56.288  0 40  TYR A CE1 1 ? 
ATOM   328  C CE2 . TYR A 1 40  ? 22.674 -10.198 40.832 1.000 59.184  0 40  TYR A CE2 1 ? 
ATOM   329  C CZ  . TYR A 1 40  ? 22.504 -10.631 39.530 1.000 58.163  0 40  TYR A CZ  1 ? 
ATOM   330  O OH  . TYR A 1 40  ? 23.367 -10.351 38.506 1.000 56.964  0 40  TYR A OH  1 ? 
ATOM   331  N N   . VAL A 1 41  ? 17.550 -9.684  40.600 1.000 54.173  0 41  VAL A N   1 ? 
ATOM   332  C CA  . VAL A 1 41  ? 16.962 -9.530  39.281 1.000 57.559  0 41  VAL A CA  1 ? 
ATOM   333  C C   . VAL A 1 41  ? 18.099 -9.241  38.309 1.000 47.016  0 41  VAL A C   1 ? 
ATOM   334  O O   . VAL A 1 41  ? 18.736 -8.190  38.373 1.000 51.101  0 41  VAL A O   1 ? 
ATOM   335  C CB  . VAL A 1 41  ? 15.920 -8.382  39.283 1.000 54.925  0 41  VAL A CB  1 ? 
ATOM   336  C CG1 . VAL A 1 41  ? 15.242 -8.227  37.929 1.000 60.674  0 41  VAL A CG1 1 ? 
ATOM   337  C CG2 . VAL A 1 41  ? 14.856 -8.568  40.360 1.000 54.045  0 41  VAL A CG2 1 ? 
ATOM   338  N N   . PRO A 1 42  ? 18.404 -10.133 37.357 1.000 47.056  0 42  PRO A N   1 ? 
ATOM   339  C CA  . PRO A 1 42  ? 19.492 -9.880  36.405 1.000 51.849  0 42  PRO A CA  1 ? 
ATOM   340  C C   . PRO A 1 42  ? 19.478 -8.472  35.820 1.000 56.700  0 42  PRO A C   1 ? 
ATOM   341  O O   . PRO A 1 42  ? 20.475 -7.736  35.931 1.000 58.806  0 42  PRO A O   1 ? 
ATOM   342  C CB  . PRO A 1 42  ? 19.264 -10.984 35.351 1.000 52.817  0 42  PRO A CB  1 ? 
ATOM   343  C CG  . PRO A 1 42  ? 18.762 -12.129 36.208 1.000 51.569  0 42  PRO A CG  1 ? 
ATOM   344  C CD  . PRO A 1 42  ? 17.784 -11.444 37.165 1.000 51.269  0 42  PRO A CD  1 ? 
ATOM   345  N N   . LEU A 1 43  ? 18.326 -8.079  35.258 1.000 58.068  0 43  LEU A N   1 ? 
ATOM   346  C CA  . LEU A 1 43  ? 18.241 -6.837  34.494 1.000 59.692  0 43  LEU A CA  1 ? 
ATOM   347  C C   . LEU A 1 43  ? 18.584 -5.620  35.352 1.000 53.293  0 43  LEU A C   1 ? 
ATOM   348  O O   . LEU A 1 43  ? 19.021 -4.620  34.805 1.000 70.294  0 43  LEU A O   1 ? 
ATOM   349  C CB  . LEU A 1 43  ? 16.864 -6.704  33.851 1.000 54.094  0 43  LEU A CB  1 ? 
ATOM   350  C CG  . LEU A 1 43  ? 16.794 -6.552  32.330 1.000 60.924  0 43  LEU A CG  1 ? 
ATOM   351  C CD1 . LEU A 1 43  ? 17.879 -7.258  31.612 1.000 59.063  0 43  LEU A CD1 1 ? 
ATOM   352  C CD2 . LEU A 1 43  ? 15.438 -7.034  31.793 1.000 58.801  0 43  LEU A CD2 1 ? 
ATOM   353  N N   . ASP A 1 44  ? 18.458 -5.714  36.682 1.000 58.157  0 44  ASP A N   1 ? 
ATOM   354  C CA  . ASP A 1 44  ? 18.853 -4.621  37.577 1.000 62.810  0 44  ASP A CA  1 ? 
ATOM   355  C C   . ASP A 1 44  ? 20.293 -4.731  38.089 1.000 50.193  0 44  ASP A C   1 ? 
ATOM   356  O O   . ASP A 1 44  ? 20.664 -3.984  38.975 1.000 58.173  0 44  ASP A O   1 ? 
ATOM   357  C CB  . ASP A 1 44  ? 18.004 -4.583  38.843 1.000 66.201  0 44  ASP A CB  1 ? 
ATOM   358  C CG  . ASP A 1 44  ? 16.510 -4.478  38.616 1.000 70.188  0 44  ASP A CG  1 ? 
ATOM   359  O OD1 . ASP A 1 44  ? 16.119 -4.100  37.480 1.000 80.861  0 44  ASP A OD1 1 ? 
ATOM   360  O OD2 . ASP A 1 44  ? 15.772 -4.852  39.545 1.000 77.958  0 44  ASP A OD2 1 ? 
ATOM   361  N N   . ASN A 1 45  ? 21.084 -5.693  37.602 1.000 54.356  0 45  ASN A N   1 ? 
ATOM   362  C CA  . ASN A 1 45  ? 22.372 -5.992  38.211 1.000 56.812  0 45  ASN A CA  1 ? 
ATOM   363  C C   . ASN A 1 45  ? 23.447 -6.209  37.143 1.000 51.743  0 45  ASN A C   1 ? 
ATOM   364  O O   . ASN A 1 45  ? 24.471 -6.809  37.421 1.000 51.051  0 45  ASN A O   1 ? 
ATOM   365  C CB  . ASN A 1 45  ? 22.221 -7.213  39.109 1.000 51.896  0 45  ASN A CB  1 ? 
ATOM   366  C CG  . ASN A 1 45  ? 21.485 -6.879  40.380 1.000 59.168  0 45  ASN A CG  1 ? 
ATOM   367  O OD1 . ASN A 1 45  ? 20.272 -7.142  40.505 1.000 60.593  0 45  ASN A OD1 1 ? 
ATOM   368  N ND2 . ASN A 1 45  ? 22.215 -6.276  41.305 1.000 51.131  0 45  ASN A ND2 1 ? 
ATOM   369  N N   . GLN A 1 46  ? 23.199 -5.777  35.907 1.000 59.171  0 46  GLN A N   1 ? 
ATOM   370  C CA  . GLN A 1 46  ? 24.187 -5.925  34.856 1.000 58.939  0 46  GLN A CA  1 ? 
ATOM   371  C C   . GLN A 1 46  ? 25.291 -4.939  35.200 1.000 53.778  0 46  GLN A C   1 ? 
ATOM   372  O O   . GLN A 1 46  ? 25.057 -3.954  35.902 1.000 48.765  0 46  GLN A O   1 ? 
ATOM   373  C CB  . GLN A 1 46  ? 23.580 -5.760  33.457 1.000 61.983  0 46  GLN A CB  1 ? 
ATOM   374  C CG  . GLN A 1 46  ? 22.353 -6.631  33.188 1.000 60.048  0 46  GLN A CG  1 ? 
ATOM   375  C CD  . GLN A 1 46  ? 22.617 -8.111  32.971 1.000 68.062  0 46  GLN A CD  1 ? 
ATOM   376  O OE1 . GLN A 1 46  ? 22.874 -8.534  31.838 1.000 68.424  0 46  GLN A OE1 1 ? 
ATOM   377  N NE2 . GLN A 1 46  ? 22.443 -8.941  34.006 1.000 64.571  0 46  GLN A NE2 1 ? 
ATOM   378  N N   . TYR A 1 47  ? 26.531 -5.267  34.843 1.000 55.803  0 47  TYR A N   1 ? 
ATOM   379  C CA  . TYR A 1 47  ? 27.644 -4.406  35.223 1.000 61.504  0 47  TYR A CA  1 ? 
ATOM   380  C C   . TYR A 1 47  ? 27.458 -3.021  34.604 1.000 60.747  0 47  TYR A C   1 ? 
ATOM   381  O O   . TYR A 1 47  ? 27.233 -2.935  33.390 1.000 63.261  0 47  TYR A O   1 ? 
ATOM   382  C CB  . TYR A 1 47  ? 28.944 -5.047  34.747 1.000 60.443  0 47  TYR A CB  1 ? 
ATOM   383  C CG  . TYR A 1 47  ? 30.217 -4.396  35.276 1.000 53.471  0 47  TYR A CG  1 ? 
ATOM   384  C CD1 . TYR A 1 47  ? 30.523 -4.424  36.632 1.000 55.222  0 47  TYR A CD1 1 ? 
ATOM   385  C CD2 . TYR A 1 47  ? 31.166 -3.870  34.409 1.000 58.853  0 47  TYR A CD2 1 ? 
ATOM   386  C CE1 . TYR A 1 47  ? 31.708 -3.888  37.120 1.000 55.962  0 47  TYR A CE1 1 ? 
ATOM   387  C CE2 . TYR A 1 47  ? 32.361 -3.346  34.876 1.000 58.775  0 47  TYR A CE2 1 ? 
ATOM   388  C CZ  . TYR A 1 47  ? 32.619 -3.332  36.235 1.000 64.256  0 47  TYR A CZ  1 ? 
ATOM   389  O OH  . TYR A 1 47  ? 33.794 -2.786  36.663 1.000 67.758  0 47  TYR A OH  1 ? 
ATOM   390  N N   . LYS A 1 48  ? 27.501 -1.983  35.454 1.000 68.417  0 48  LYS A N   1 ? 
ATOM   391  C CA  . LYS A 1 48  ? 27.187 -0.595  35.093 1.000 84.500  0 48  LYS A CA  1 ? 
ATOM   392  C C   . LYS A 1 48  ? 25.911 -0.421  34.223 1.000 81.071  0 48  LYS A C   1 ? 
ATOM   393  O O   . LYS A 1 48  ? 25.911 0.290   33.218 1.000 76.744  0 48  LYS A O   1 ? 
ATOM   394  C CB  . LYS A 1 48  ? 28.454 -0.088  34.379 1.000 80.471  0 48  LYS A CB  1 ? 
ATOM   395  C CG  . LYS A 1 48  ? 29.779 0.020   35.163 1.000 73.009  0 48  LYS A CG  1 ? 
ATOM   396  C CD  . LYS A 1 48  ? 30.974 0.234   34.235 1.000 63.182  0 48  LYS A CD  1 ? 
ATOM   397  C CE  . LYS A 1 48  ? 32.305 0.490   34.918 1.000 63.760  0 48  LYS A CE  1 ? 
ATOM   398  N NZ  . LYS A 1 48  ? 33.368 0.595   33.911 1.000 55.255  0 48  LYS A NZ  1 ? 
ATOM   399  N N   . GLY A 1 49  ? 24.782 -1.041  34.581 1.000 73.072  0 49  GLY A N   1 ? 
ATOM   400  C CA  . GLY A 1 49  ? 23.526 -0.837  33.859 1.000 74.340  0 49  GLY A CA  1 ? 
ATOM   401  C C   . GLY A 1 49  ? 23.503 -1.322  32.388 1.000 73.185  0 49  GLY A C   1 ? 
ATOM   402  O O   . GLY A 1 49  ? 22.508 -1.146  31.683 1.000 60.991  0 49  GLY A O   1 ? 
ATOM   403  N N   . ILE A 1 50  ? 24.565 -1.969  31.901 1.000 70.474  0 50  ILE A N   1 ? 
ATOM   404  C CA  . ILE A 1 50  ? 24.722 -2.162  30.467 1.000 85.662  0 50  ILE A CA  1 ? 
ATOM   405  C C   . ILE A 1 50  ? 23.866 -3.349  29.990 1.000 93.713  0 50  ILE A C   1 ? 
ATOM   406  O O   . ILE A 1 50  ? 23.822 -4.426  30.607 1.000 80.836  0 50  ILE A O   1 ? 
ATOM   407  C CB  . ILE A 1 50  ? 26.213 -2.301  30.085 1.000 82.234  0 50  ILE A CB  1 ? 
ATOM   408  N N   . ARG A 1 51  ? 23.143 -3.129  28.882 1.000 65.092  0 51  ARG A N   1 ? 
ATOM   409  C CA  . ARG A 1 51  ? 22.583 -4.217  28.103 1.000 77.752  0 51  ARG A CA  1 ? 
ATOM   410  C C   . ARG A 1 51  ? 22.846 -3.937  26.635 1.000 73.279  0 51  ARG A C   1 ? 
ATOM   411  O O   . ARG A 1 51  ? 22.687 -2.829  26.164 1.000 58.549  0 51  ARG A O   1 ? 
ATOM   412  C CB  . ARG A 1 51  ? 21.089 -4.475  28.345 1.000 90.001  0 51  ARG A CB  1 ? 
ATOM   413  C CG  . ARG A 1 51  ? 20.325 -3.224  28.751 1.000 102.860 0 51  ARG A CG  1 ? 
ATOM   414  C CD  . ARG A 1 51  ? 18.903 -3.564  29.110 1.000 96.903  0 51  ARG A CD  1 ? 
ATOM   415  N NE  . ARG A 1 51  ? 18.155 -4.165  28.000 1.000 83.792  0 51  ARG A NE  1 ? 
ATOM   416  C CZ  . ARG A 1 51  ? 16.882 -4.568  28.086 1.000 80.218  0 51  ARG A CZ  1 ? 
ATOM   417  N NH1 . ARG A 1 51  ? 16.167 -4.301  29.167 1.000 83.401  0 51  ARG A NH1 1 ? 
ATOM   418  N NH2 . ARG A 1 51  ? 16.322 -5.231  27.088 1.000 63.764  0 51  ARG A NH2 1 ? 
ATOM   419  N N   . VAL A 1 52  ? 23.260 -4.980  25.922 1.000 96.986  0 52  VAL A N   1 ? 
ATOM   420  C CA  . VAL A 1 52  ? 23.796 -4.868  24.571 1.000 98.296  0 52  VAL A CA  1 ? 
ATOM   421  C C   . VAL A 1 52  ? 22.753 -4.319  23.590 1.000 94.328  0 52  VAL A C   1 ? 
ATOM   422  O O   . VAL A 1 52  ? 23.093 -4.047  22.441 1.000 74.628  0 52  VAL A O   1 ? 
ATOM   423  C CB  . VAL A 1 52  ? 24.380 -6.246  24.164 1.000 108.221 0 52  VAL A CB  1 ? 
ATOM   424  C CG1 . VAL A 1 52  ? 23.892 -6.768  22.809 1.000 113.862 0 52  VAL A CG1 1 ? 
ATOM   425  C CG2 . VAL A 1 52  ? 25.907 -6.255  24.259 1.000 91.491  0 52  VAL A CG2 1 ? 
ATOM   426  N N   . ASP A 1 53  ? 21.492 -4.148  24.024 1.000 100.329 0 53  ASP A N   1 ? 
ATOM   427  C CA  . ASP A 1 53  ? 20.491 -3.487  23.193 1.000 94.731  0 53  ASP A CA  1 ? 
ATOM   428  C C   . ASP A 1 53  ? 20.535 -1.974  23.444 1.000 74.180  0 53  ASP A C   1 ? 
ATOM   429  O O   . ASP A 1 53  ? 20.387 -1.225  22.490 1.000 81.745  0 53  ASP A O   1 ? 
ATOM   430  C CB  . ASP A 1 53  ? 19.117 -4.154  23.289 1.000 99.085  0 53  ASP A CB  1 ? 
ATOM   431  C CG  . ASP A 1 53  ? 18.368 -4.001  24.606 1.000 94.731  0 53  ASP A CG  1 ? 
ATOM   432  O OD1 . ASP A 1 53  ? 19.010 -4.168  25.666 1.000 72.187  0 53  ASP A OD1 1 ? 
ATOM   433  O OD2 . ASP A 1 53  ? 17.151 -3.691  24.560 1.000 104.714 0 53  ASP A OD2 1 ? 
ATOM   434  N N   . GLU A 1 54  ? 20.731 -1.526  24.699 1.000 68.503  0 54  GLU A N   1 ? 
ATOM   435  C CA  . GLU A 1 54  ? 20.765 -0.103  25.032 1.000 75.747  0 54  GLU A CA  1 ? 
ATOM   436  C C   . GLU A 1 54  ? 22.136 0.566   24.864 1.000 83.926  0 54  GLU A C   1 ? 
ATOM   437  O O   . GLU A 1 54  ? 22.183 1.755   24.574 1.000 77.675  0 54  GLU A O   1 ? 
ATOM   438  C CB  . GLU A 1 54  ? 20.297 0.180   26.451 1.000 71.100  0 54  GLU A CB  1 ? 
ATOM   439  C CG  . GLU A 1 54  ? 18.797 0.439   26.464 1.000 87.829  0 54  GLU A CG  1 ? 
ATOM   440  C CD  . GLU A 1 54  ? 18.107 0.031   27.733 1.000 86.737  0 54  GLU A CD  1 ? 
ATOM   441  O OE1 . GLU A 1 54  ? 17.048 -0.643  27.636 1.000 85.595  0 54  GLU A OE1 1 ? 
ATOM   442  O OE2 . GLU A 1 54  ? 18.655 0.404   28.795 1.000 82.086  0 54  GLU A OE2 1 ? 
ATOM   443  N N   . HIS A 1 55  ? 23.235 -0.159  25.110 1.000 78.773  0 55  HIS A N   1 ? 
ATOM   444  C CA  . HIS A 1 55  ? 24.586 0.348   24.888 1.000 62.795  0 55  HIS A CA  1 ? 
ATOM   445  C C   . HIS A 1 55  ? 25.393 -0.729  24.169 1.000 55.149  0 55  HIS A C   1 ? 
ATOM   446  O O   . HIS A 1 55  ? 26.214 -1.380  24.783 1.000 75.533  0 55  HIS A O   1 ? 
ATOM   447  C CB  . HIS A 1 55  ? 25.223 0.793   26.204 1.000 56.904  0 55  HIS A CB  1 ? 
ATOM   448  C CG  . HIS A 1 55  ? 24.420 1.785   27.024 1.000 59.836  0 55  HIS A CG  1 ? 
ATOM   449  N ND1 . HIS A 1 55  ? 24.434 3.143   26.795 1.000 65.942  0 55  HIS A ND1 1 ? 
ATOM   450  C CD2 . HIS A 1 55  ? 23.633 1.630   28.115 1.000 70.979  0 55  HIS A CD2 1 ? 
ATOM   451  C CE1 . HIS A 1 55  ? 23.665 3.773   27.697 1.000 61.325  0 55  HIS A CE1 1 ? 
ATOM   452  N NE2 . HIS A 1 55  ? 23.157 2.875   28.516 1.000 60.525  0 55  HIS A NE2 1 ? 
ATOM   453  N N   . PRO A 1 56  ? 25.129 -0.989  22.868 1.000 54.228  0 56  PRO A N   1 ? 
ATOM   454  C CA  . PRO A 1 56  ? 25.800 -2.022  22.081 1.000 58.101  0 56  PRO A CA  1 ? 
ATOM   455  C C   . PRO A 1 56  ? 27.324 -1.989  21.997 1.000 75.410  0 56  PRO A C   1 ? 
ATOM   456  O O   . PRO A 1 56  ? 27.930 -2.849  21.338 1.000 69.061  0 56  PRO A O   1 ? 
ATOM   457  C CB  . PRO A 1 56  ? 25.238 -1.826  20.638 1.000 55.630  0 56  PRO A CB  1 ? 
ATOM   458  C CG  . PRO A 1 56  ? 23.909 -1.152  20.839 1.000 66.462  0 56  PRO A CG  1 ? 
ATOM   459  C CD  . PRO A 1 56  ? 24.094 -0.297  22.085 1.000 67.411  0 56  PRO A CD  1 ? 
ATOM   460  N N   . GLU A 1 57  ? 27.929 -0.942  22.570 1.000 72.611  0 57  GLU A N   1 ? 
ATOM   461  C CA  . GLU A 1 57  ? 29.376 -0.817  22.562 1.000 74.173  0 57  GLU A CA  1 ? 
ATOM   462  C C   . GLU A 1 57  ? 29.968 -1.919  23.441 1.000 66.812  0 57  GLU A C   1 ? 
ATOM   463  O O   . GLU A 1 57  ? 31.120 -2.249  23.265 1.000 61.779  0 57  GLU A O   1 ? 
ATOM   464  C CB  . GLU A 1 57  ? 29.888 0.579   22.945 1.000 59.803  0 57  GLU A CB  1 ? 
ATOM   465  C CG  . GLU A 1 57  ? 29.400 1.119   24.288 1.000 61.796  0 57  GLU A CG  1 ? 
ATOM   466  C CD  . GLU A 1 57  ? 28.151 1.991   24.212 1.000 61.650  0 57  GLU A CD  1 ? 
ATOM   467  O OE1 . GLU A 1 57  ? 27.282 1.754   23.315 1.000 52.901  0 57  GLU A OE1 1 ? 
ATOM   468  O OE2 . GLU A 1 57  ? 28.035 2.898   25.070 1.000 54.629  0 57  GLU A OE2 1 ? 
ATOM   469  N N   . TYR A 1 58  ? 29.176 -2.510  24.351 1.000 77.496  0 58  TYR A N   1 ? 
ATOM   470  C CA  . TYR A 1 58  ? 29.666 -3.550  25.250 1.000 75.636  0 58  TYR A CA  1 ? 
ATOM   471  C C   . TYR A 1 58  ? 29.515 -4.960  24.654 1.000 67.745  0 58  TYR A C   1 ? 
ATOM   472  O O   . TYR A 1 58  ? 29.853 -5.941  25.303 1.000 79.540  0 58  TYR A O   1 ? 
ATOM   473  C CB  . TYR A 1 58  ? 28.978 -3.354  26.597 1.000 68.080  0 58  TYR A CB  1 ? 
ATOM   474  C CG  . TYR A 1 58  ? 29.246 -2.036  27.314 1.000 80.906  0 58  TYR A CG  1 ? 
ATOM   475  C CD1 . TYR A 1 58  ? 30.368 -1.865  28.121 1.000 94.603  0 58  TYR A CD1 1 ? 
ATOM   476  C CD2 . TYR A 1 58  ? 28.356 -0.975  27.228 1.000 85.423  0 58  TYR A CD2 1 ? 
ATOM   477  C CE1 . TYR A 1 58  ? 30.607 -0.676  28.795 1.000 97.149  0 58  TYR A CE1 1 ? 
ATOM   478  C CE2 . TYR A 1 58  ? 28.583 0.221   27.895 1.000 81.245  0 58  TYR A CE2 1 ? 
ATOM   479  C CZ  . TYR A 1 58  ? 29.716 0.378   28.674 1.000 86.765  0 58  TYR A CZ  1 ? 
ATOM   480  O OH  . TYR A 1 58  ? 29.932 1.556   29.342 1.000 75.353  0 58  TYR A OH  1 ? 
ATOM   481  N N   . LEU A 1 59  ? 29.150 -5.081  23.373 1.000 81.411  0 59  LEU A N   1 ? 
ATOM   482  C CA  . LEU A 1 59  ? 28.985 -6.371  22.697 1.000 89.648  0 59  LEU A CA  1 ? 
ATOM   483  C C   . LEU A 1 59  ? 30.282 -7.190  22.708 1.000 90.652  0 59  LEU A C   1 ? 
ATOM   484  O O   . LEU A 1 59  ? 30.234 -8.391  22.427 1.000 75.949  0 59  LEU A O   1 ? 
ATOM   485  C CB  . LEU A 1 59  ? 28.536 -6.211  21.235 1.000 89.383  0 59  LEU A CB  1 ? 
ATOM   486  C CG  . LEU A 1 59  ? 27.038 -6.221  20.891 1.000 94.646  0 59  LEU A CG  1 ? 
ATOM   487  C CD1 . LEU A 1 59  ? 26.781 -5.593  19.530 1.000 93.236  0 59  LEU A CD1 1 ? 
ATOM   488  C CD2 . LEU A 1 59  ? 26.459 -7.625  20.887 1.000 89.092  0 59  LEU A CD2 1 ? 
ATOM   489  N N   . HIS A 1 60  ? 31.428 -6.507  22.823 1.000 95.798  0 60  HIS A N   1 ? 
ATOM   490  C CA  . HIS A 1 60  ? 32.726 -7.132  22.623 1.000 100.208 0 60  HIS A CA  1 ? 
ATOM   491  C C   . HIS A 1 60  ? 33.621 -6.809  23.817 1.000 92.625  0 60  HIS A C   1 ? 
ATOM   492  O O   . HIS A 1 60  ? 34.798 -7.158  23.777 1.000 88.933  0 60  HIS A O   1 ? 
ATOM   493  C CB  . HIS A 1 60  ? 33.375 -6.710  21.282 1.000 104.819 0 60  HIS A CB  1 ? 
ATOM   494  C CG  . HIS A 1 60  ? 32.750 -7.225  20.003 1.000 90.595  0 60  HIS A CG  1 ? 
ATOM   495  N ND1 . HIS A 1 60  ? 31.885 -6.458  19.237 1.000 88.057  0 60  HIS A ND1 1 ? 
ATOM   496  C CD2 . HIS A 1 60  ? 32.877 -8.404  19.334 1.000 74.618  0 60  HIS A CD2 1 ? 
ATOM   497  C CE1 . HIS A 1 60  ? 31.497 -7.157  18.156 1.000 81.430  0 60  HIS A CE1 1 ? 
ATOM   498  N NE2 . HIS A 1 60  ? 32.081 -8.345  18.194 1.000 64.844  0 60  HIS A NE2 1 ? 
ATOM   499  N N   . ASP A 1 61  ? 33.067 -6.154  24.859 1.000 72.017  0 61  ASP A N   1 ? 
ATOM   500  C CA  . ASP A 1 61  ? 33.799 -5.852  26.084 1.000 69.344  0 61  ASP A CA  1 ? 
ATOM   501  C C   . ASP A 1 61  ? 33.824 -7.067  27.038 1.000 74.147  0 61  ASP A C   1 ? 
ATOM   502  O O   . ASP A 1 61  ? 32.800 -7.470  27.579 1.000 74.557  0 61  ASP A O   1 ? 
ATOM   503  C CB  . ASP A 1 61  ? 33.237 -4.620  26.778 1.000 59.561  0 61  ASP A CB  1 ? 
ATOM   504  C CG  . ASP A 1 61  ? 33.939 -4.284  28.083 1.000 67.626  0 61  ASP A CG  1 ? 
ATOM   505  O OD1 . ASP A 1 61  ? 34.826 -5.058  28.460 1.000 82.845  0 61  ASP A OD1 1 ? 
ATOM   506  O OD2 . ASP A 1 61  ? 33.595 -3.279  28.746 1.000 66.141  0 61  ASP A OD2 1 ? 
ATOM   507  N N   . LYS A 1 62  ? 35.020 -7.629  27.268 1.000 60.811  0 62  LYS A N   1 ? 
ATOM   508  C CA  . LYS A 1 62  ? 35.192 -8.829  28.068 1.000 59.736  0 62  LYS A CA  1 ? 
ATOM   509  C C   . LYS A 1 62  ? 35.065 -8.526  29.567 1.000 53.561  0 62  LYS A C   1 ? 
ATOM   510  O O   . LYS A 1 62  ? 34.761 -9.406  30.365 1.000 55.408  0 62  LYS A O   1 ? 
ATOM   511  C CB  . LYS A 1 62  ? 36.553 -9.459  27.749 1.000 59.966  0 62  LYS A CB  1 ? 
ATOM   512  C CG  . LYS A 1 62  ? 36.681 -9.986  26.320 1.000 62.930  0 62  LYS A CG  1 ? 
ATOM   513  C CD  . LYS A 1 62  ? 38.085 -10.509 26.039 1.000 68.215  0 62  LYS A CD  1 ? 
ATOM   514  C CE  . LYS A 1 62  ? 38.188 -11.394 24.836 1.000 70.253  0 62  LYS A CE  1 ? 
ATOM   515  N NZ  . LYS A 1 62  ? 38.198 -10.593 23.610 1.000 74.894  0 62  LYS A NZ  1 ? 
ATOM   516  N N   . VAL A 1 63  ? 35.340 -7.290  29.965 1.000 54.634  0 63  VAL A N   1 ? 
ATOM   517  C CA  . VAL A 1 63  ? 35.236 -6.881  31.358 1.000 58.087  0 63  VAL A CA  1 ? 
ATOM   518  C C   . VAL A 1 63  ? 33.759 -6.834  31.770 1.000 64.746  0 63  VAL A C   1 ? 
ATOM   519  O O   . VAL A 1 63  ? 33.360 -7.418  32.780 1.000 71.227  0 63  VAL A O   1 ? 
ATOM   520  C CB  . VAL A 1 63  ? 35.950 -5.526  31.560 1.000 56.909  0 63  VAL A CB  1 ? 
ATOM   521  C CG1 . VAL A 1 63  ? 35.773 -4.948  32.963 1.000 54.748  0 63  VAL A CG1 1 ? 
ATOM   522  C CG2 . VAL A 1 63  ? 37.439 -5.597  31.207 1.000 63.193  0 63  VAL A CG2 1 ? 
ATOM   523  N N   . TRP A 1 64  ? 32.935 -6.149  30.972 1.000 64.770  0 64  TRP A N   1 ? 
ATOM   524  C CA  . TRP A 1 64  ? 31.508 -6.125  31.222 1.000 68.542  0 64  TRP A CA  1 ? 
ATOM   525  C C   . TRP A 1 64  ? 30.967 -7.559  31.263 1.000 60.694  0 64  TRP A C   1 ? 
ATOM   526  O O   . TRP A 1 64  ? 30.227 -7.889  32.173 1.000 57.787  0 64  TRP A O   1 ? 
ATOM   527  C CB  . TRP A 1 64  ? 30.773 -5.250  30.188 1.000 69.901  0 64  TRP A CB  1 ? 
ATOM   528  C CG  . TRP A 1 64  ? 29.277 -5.412  30.266 1.000 63.392  0 64  TRP A CG  1 ? 
ATOM   529  C CD1 . TRP A 1 64  ? 28.402 -4.768  31.098 1.000 54.054  0 64  TRP A CD1 1 ? 
ATOM   530  C CD2 . TRP A 1 64  ? 28.515 -6.394  29.541 1.000 54.521  0 64  TRP A CD2 1 ? 
ATOM   531  N NE1 . TRP A 1 64  ? 27.141 -5.270  30.907 1.000 62.242  0 64  TRP A NE1 1 ? 
ATOM   532  C CE2 . TRP A 1 64  ? 27.182 -6.270  29.970 1.000 55.021  0 64  TRP A CE2 1 ? 
ATOM   533  C CE3 . TRP A 1 64  ? 28.834 -7.354  28.573 1.000 69.692  0 64  TRP A CE3 1 ? 
ATOM   534  C CZ2 . TRP A 1 64  ? 26.169 -7.065  29.451 1.000 56.792  0 64  TRP A CZ2 1 ? 
ATOM   535  C CZ3 . TRP A 1 64  ? 27.830 -8.148  28.064 1.000 72.529  0 64  TRP A CZ3 1 ? 
ATOM   536  C CH2 . TRP A 1 64  ? 26.516 -8.020  28.521 1.000 61.435  0 64  TRP A CH2 1 ? 
ATOM   537  N N   . ALA A 1 65  ? 31.361 -8.400  30.304 1.000 51.482  0 65  ALA A N   1 ? 
ATOM   538  C CA  . ALA A 1 65  ? 30.866 -9.755  30.213 1.000 53.542  0 65  ALA A CA  1 ? 
ATOM   539  C C   . ALA A 1 65  ? 31.272 -10.581 31.436 1.000 56.677  0 65  ALA A C   1 ? 
ATOM   540  O O   . ALA A 1 65  ? 30.439 -11.278 32.002 1.000 52.672  0 65  ALA A O   1 ? 
ATOM   541  C CB  . ALA A 1 65  ? 31.347 -10.388 28.936 1.000 51.329  0 65  ALA A CB  1 ? 
ATOM   542  N N   . THR A 1 66  ? 32.539 -10.480 31.853 1.000 55.183  0 66  THR A N   1 ? 
ATOM   543  C CA  . THR A 1 66  ? 33.031 -11.214 33.011 1.000 56.561  0 66  THR A CA  1 ? 
ATOM   544  C C   . THR A 1 66  ? 32.217 -10.854 34.254 1.000 54.093  0 66  THR A C   1 ? 
ATOM   545  O O   . THR A 1 66  ? 31.744 -11.737 34.968 1.000 51.218  0 66  THR A O   1 ? 
ATOM   546  C CB  . THR A 1 66  ? 34.516 -10.954 33.253 1.000 52.949  0 66  THR A CB  1 ? 
ATOM   547  O OG1 . THR A 1 66  ? 35.225 -11.457 32.130 1.000 48.239  0 66  THR A OG1 1 ? 
ATOM   548  C CG2 . THR A 1 66  ? 35.044 -11.714 34.453 1.000 57.361  0 66  THR A CG2 1 ? 
ATOM   549  N N   . ALA A 1 67  ? 32.088 -9.556  34.526 1.000 53.799  0 67  ALA A N   1 ? 
ATOM   550  C CA  . ALA A 1 67  ? 31.457 -9.097  35.758 1.000 53.803  0 67  ALA A CA  1 ? 
ATOM   551  C C   . ALA A 1 67  ? 29.967 -9.437  35.771 1.000 53.970  0 67  ALA A C   1 ? 
ATOM   552  O O   . ALA A 1 67  ? 29.444 -9.878  36.783 1.000 50.877  0 67  ALA A O   1 ? 
ATOM   553  C CB  . ALA A 1 67  ? 31.658 -7.622  35.920 1.000 49.965  0 67  ALA A CB  1 ? 
ATOM   554  N N   . THR A 1 68  ? 29.287 -9.259  34.638 1.000 49.708  0 68  THR A N   1 ? 
ATOM   555  C CA  . THR A 1 68  ? 27.864 -9.549  34.559 1.000 54.891  0 68  THR A CA  1 ? 
ATOM   556  C C   . THR A 1 68  ? 27.643 -11.052 34.746 1.000 52.087  0 68  THR A C   1 ? 
ATOM   557  O O   . THR A 1 68  ? 26.758 -11.462 35.485 1.000 56.943  0 68  THR A O   1 ? 
ATOM   558  C CB  . THR A 1 68  ? 27.291 -9.052  33.229 1.000 49.224  0 68  THR A CB  1 ? 
ATOM   559  O OG1 . THR A 1 68  ? 27.609 -7.663  33.167 1.000 50.641  0 68  THR A OG1 1 ? 
ATOM   560  C CG2 . THR A 1 68  ? 25.780 -9.160  33.125 1.000 50.901  0 68  THR A CG2 1 ? 
ATOM   561  N N   . TYR A 1 69  ? 28.440 -11.874 34.067 1.000 56.474  0 69  TYR A N   1 ? 
ATOM   562  C CA  . TYR A 1 69  ? 28.311 -13.316 34.192 1.000 52.772  0 69  TYR A CA  1 ? 
ATOM   563  C C   . TYR A 1 69  ? 28.459 -13.711 35.658 1.000 51.026  0 69  TYR A C   1 ? 
ATOM   564  O O   . TYR A 1 69  ? 27.602 -14.405 36.201 1.000 47.788  0 69  TYR A O   1 ? 
ATOM   565  C CB  . TYR A 1 69  ? 29.326 -14.024 33.302 1.000 49.830  0 69  TYR A CB  1 ? 
ATOM   566  C CG  . TYR A 1 69  ? 29.379 -15.532 33.509 1.000 49.219  0 69  TYR A CG  1 ? 
ATOM   567  C CD1 . TYR A 1 69  ? 28.320 -16.351 33.136 1.000 49.862  0 69  TYR A CD1 1 ? 
ATOM   568  C CD2 . TYR A 1 69  ? 30.510 -16.135 34.051 1.000 47.459  0 69  TYR A CD2 1 ? 
ATOM   569  C CE1 . TYR A 1 69  ? 28.396 -17.731 33.256 1.000 48.989  0 69  TYR A CE1 1 ? 
ATOM   570  C CE2 . TYR A 1 69  ? 30.588 -17.512 34.204 1.000 54.957  0 69  TYR A CE2 1 ? 
ATOM   571  C CZ  . TYR A 1 69  ? 29.533 -18.313 33.794 1.000 53.157  0 69  TYR A CZ  1 ? 
ATOM   572  O OH  . TYR A 1 69  ? 29.588 -19.670 33.983 1.000 51.852  0 69  TYR A OH  1 ? 
ATOM   573  N N   . ASN A 1 70  ? 29.529 -13.228 36.291 1.000 44.928  0 70  ASN A N   1 ? 
ATOM   574  C CA  . ASN A 1 70  ? 29.823 -13.555 37.676 1.000 52.833  0 70  ASN A CA  1 ? 
ATOM   575  C C   . ASN A 1 70  ? 28.694 -13.097 38.598 1.000 59.774  0 70  ASN A C   1 ? 
ATOM   576  O O   . ASN A 1 70  ? 28.355 -13.788 39.561 1.000 61.816  0 70  ASN A O   1 ? 
ATOM   577  C CB  . ASN A 1 70  ? 31.186 -13.001 38.079 1.000 54.589  0 70  ASN A CB  1 ? 
ATOM   578  C CG  . ASN A 1 70  ? 32.304 -13.954 37.723 1.000 55.488  0 70  ASN A CG  1 ? 
ATOM   579  O OD1 . ASN A 1 70  ? 32.616 -14.855 38.494 1.000 77.454  0 70  ASN A OD1 1 ? 
ATOM   580  N ND2 . ASN A 1 70  ? 32.957 -13.768 36.595 1.000 58.441  0 70  ASN A ND2 1 ? 
ATOM   581  N N   . ASN A 1 71  ? 28.096 -11.946 38.273 1.000 62.436  0 71  ASN A N   1 ? 
ATOM   582  C CA  . ASN A 1 71  ? 27.072 -11.348 39.116 1.000 62.105  0 71  ASN A CA  1 ? 
ATOM   583  C C   . ASN A 1 71  ? 25.807 -12.203 39.100 1.000 52.605  0 71  ASN A C   1 ? 
ATOM   584  O O   . ASN A 1 71  ? 25.222 -12.453 40.142 1.000 54.381  0 71  ASN A O   1 ? 
ATOM   585  C CB  . ASN A 1 71  ? 26.773 -9.903  38.725 1.000 57.166  0 71  ASN A CB  1 ? 
ATOM   586  C CG  . ASN A 1 71  ? 26.450 -9.035  39.916 1.000 55.493  0 71  ASN A CG  1 ? 
ATOM   587  O OD1 . ASN A 1 71  ? 25.923 -7.935  39.756 1.000 62.751  0 71  ASN A OD1 1 ? 
ATOM   588  N ND2 . ASN A 1 71  ? 26.622 -9.539  41.125 1.000 64.690  0 71  ASN A ND2 1 ? 
ATOM   589  N N   . ASP A 1 72  ? 25.426 -12.669 37.921 1.000 46.946  0 72  ASP A N   1 ? 
ATOM   590  C CA  . ASP A 1 72  ? 24.322 -13.590 37.743 1.000 53.538  0 72  ASP A CA  1 ? 
ATOM   591  C C   . ASP A 1 72  ? 24.567 -14.892 38.514 1.000 60.470  0 72  ASP A C   1 ? 
ATOM   592  O O   . ASP A 1 72  ? 23.701 -15.368 39.248 1.000 69.865  0 72  ASP A O   1 ? 
ATOM   593  C CB  . ASP A 1 72  ? 24.007 -13.746 36.266 1.000 53.262  0 72  ASP A CB  1 ? 
ATOM   594  C CG  . ASP A 1 72  ? 23.213 -12.602 35.631 1.000 57.561  0 72  ASP A CG  1 ? 
ATOM   595  O OD1 . ASP A 1 72  ? 23.214 -11.461 36.140 1.000 56.065  0 72  ASP A OD1 1 ? 
ATOM   596  O OD2 . ASP A 1 72  ? 22.598 -12.848 34.602 1.000 62.337  0 72  ASP A OD2 1 ? 
ATOM   597  N N   . LEU A 1 73  ? 25.774 -15.452 38.419 1.000 55.007  0 73  LEU A N   1 ? 
ATOM   598  C CA  . LEU A 1 73  ? 26.054 -16.683 39.141 1.000 52.725  0 73  LEU A CA  1 ? 
ATOM   599  C C   . LEU A 1 73  ? 25.935 -16.401 40.635 1.000 50.707  0 73  LEU A C   1 ? 
ATOM   600  O O   . LEU A 1 73  ? 25.359 -17.168 41.394 1.000 46.915  0 73  LEU A O   1 ? 
ATOM   601  C CB  . LEU A 1 73  ? 27.424 -17.246 38.768 1.000 53.705  0 73  LEU A CB  1 ? 
ATOM   602  C CG  . LEU A 1 73  ? 27.585 -17.742 37.323 1.000 63.083  0 73  LEU A CG  1 ? 
ATOM   603  C CD1 . LEU A 1 73  ? 28.770 -18.718 37.259 1.000 71.981  0 73  LEU A CD1 1 ? 
ATOM   604  C CD2 . LEU A 1 73  ? 26.339 -18.368 36.731 1.000 68.153  0 73  LEU A CD2 1 ? 
ATOM   605  N N   . ASN A 1 74  ? 26.496 -15.280 41.055 1.000 49.711  0 74  ASN A N   1 ? 
ATOM   606  C CA  . ASN A 1 74  ? 26.445 -14.866 42.441 1.000 51.566  0 74  ASN A CA  1 ? 
ATOM   607  C C   . ASN A 1 74  ? 25.006 -14.689 42.950 1.000 52.378  0 74  ASN A C   1 ? 
ATOM   608  O O   . ASN A 1 74  ? 24.671 -15.027 44.098 1.000 52.198  0 74  ASN A O   1 ? 
ATOM   609  C CB  . ASN A 1 74  ? 27.218 -13.573 42.554 1.000 51.998  0 74  ASN A CB  1 ? 
ATOM   610  C CG  . ASN A 1 74  ? 27.275 -13.116 43.977 1.000 59.725  0 74  ASN A CG  1 ? 
ATOM   611  O OD1 . ASN A 1 74  ? 26.614 -12.124 44.317 1.000 62.766  0 74  ASN A OD1 1 ? 
ATOM   612  N ND2 . ASN A 1 74  ? 28.035 -13.848 44.786 1.000 57.181  0 74  ASN A ND2 1 ? 
ATOM   613  N N   . GLY A 1 75  ? 24.157 -14.138 42.089 1.000 53.793  0 75  GLY A N   1 ? 
ATOM   614  C CA  . GLY A 1 75  ? 22.755 -13.933 42.405 1.000 51.371  0 75  GLY A CA  1 ? 
ATOM   615  C C   . GLY A 1 75  ? 22.023 -15.256 42.611 1.000 53.451  0 75  GLY A C   1 ? 
ATOM   616  O O   . GLY A 1 75  ? 21.099 -15.341 43.410 1.000 49.385  0 75  GLY A O   1 ? 
ATOM   617  N N   . ILE A 1 76  ? 22.440 -16.308 41.899 1.000 49.700  0 76  ILE A N   1 ? 
ATOM   618  C CA  . ILE A 1 76  ? 21.835 -17.613 42.121 1.000 49.993  0 76  ILE A CA  1 ? 
ATOM   619  C C   . ILE A 1 76  ? 22.331 -18.207 43.426 1.000 51.475  0 76  ILE A C   1 ? 
ATOM   620  O O   . ILE A 1 76  ? 21.536 -18.630 44.279 1.000 47.971  0 76  ILE A O   1 ? 
ATOM   621  C CB  . ILE A 1 76  ? 22.097 -18.561 40.950 1.000 52.628  0 76  ILE A CB  1 ? 
ATOM   622  C CG1 . ILE A 1 76  ? 21.445 -18.027 39.664 1.000 52.667  0 76  ILE A CG1 1 ? 
ATOM   623  C CG2 . ILE A 1 76  ? 21.614 -19.962 41.311 1.000 48.773  0 76  ILE A CG2 1 ? 
ATOM   624  C CD1 . ILE A 1 76  ? 21.918 -18.707 38.390 1.000 54.755  0 76  ILE A CD1 1 ? 
ATOM   625  N N   . LYS A 1 77  ? 23.657 -18.217 43.592 1.000 52.685  0 77  LYS A N   1 ? 
ATOM   626  C CA  . LYS A 1 77  ? 24.234 -18.941 44.711 1.000 51.251  0 77  LYS A CA  1 ? 
ATOM   627  C C   . LYS A 1 77  ? 23.873 -18.276 46.047 1.000 46.174  0 77  LYS A C   1 ? 
ATOM   628  O O   . LYS A 1 77  ? 23.737 -18.986 47.009 1.000 40.686  0 77  LYS A O   1 ? 
ATOM   629  C CB  . LYS A 1 77  ? 25.742 -19.146 44.521 1.000 54.195  0 77  LYS A CB  1 ? 
ATOM   630  C CG  . LYS A 1 77  ? 26.659 -18.059 45.028 1.000 52.867  0 77  LYS A CG  1 ? 
ATOM   631  C CD  . LYS A 1 77  ? 28.066 -18.045 44.423 1.000 56.338  0 77  LYS A CD  1 ? 
ATOM   632  C CE  . LYS A 1 77  ? 28.898 -17.156 45.296 1.000 51.316  0 77  LYS A CE  1 ? 
ATOM   633  N NZ  . LYS A 1 77  ? 30.168 -16.706 44.775 1.000 56.229  0 77  LYS A NZ  1 ? 
ATOM   634  N N   . THR A 1 78  ? 23.640 -16.953 46.118 1.000 50.176  0 78  THR A N   1 ? 
ATOM   635  C CA  . THR A 1 78  ? 23.378 -16.313 47.412 1.000 49.244  0 78  THR A CA  1 ? 
ATOM   636  C C   . THR A 1 78  ? 21.878 -16.141 47.706 1.000 51.135  0 78  THR A C   1 ? 
ATOM   637  O O   . THR A 1 78  ? 21.514 -15.522 48.680 1.000 47.649  0 78  THR A O   1 ? 
ATOM   638  C CB  . THR A 1 78  ? 24.047 -14.945 47.440 1.000 53.168  0 78  THR A CB  1 ? 
ATOM   639  O OG1 . THR A 1 78  ? 23.428 -14.204 46.383 1.000 54.013  0 78  THR A OG1 1 ? 
ATOM   640  C CG2 . THR A 1 78  ? 25.549 -15.054 47.251 1.000 53.370  0 78  THR A CG2 1 ? 
ATOM   641  N N   . ASN A 1 79  ? 20.982 -16.638 46.866 1.000 51.693  0 79  ASN A N   1 ? 
ATOM   642  C CA  . ASN A 1 79  ? 19.552 -16.534 47.124 1.000 48.608  0 79  ASN A CA  1 ? 
ATOM   643  C C   . ASN A 1 79  ? 18.963 -17.929 47.329 1.000 50.724  0 79  ASN A C   1 ? 
ATOM   644  O O   . ASN A 1 79  ? 19.571 -18.952 47.000 1.000 49.139  0 79  ASN A O   1 ? 
ATOM   645  C CB  . ASN A 1 79  ? 18.864 -15.702 46.041 1.000 53.474  0 79  ASN A CB  1 ? 
ATOM   646  C CG  . ASN A 1 79  ? 19.153 -14.226 46.260 1.000 46.591  0 79  ASN A CG  1 ? 
ATOM   647  O OD1 . ASN A 1 79  ? 18.824 -13.690 47.317 1.000 57.353  0 79  ASN A OD1 1 ? 
ATOM   648  N ND2 . ASN A 1 79  ? 19.802 -13.550 45.332 1.000 50.148  0 79  ASN A ND2 1 ? 
ATOM   649  N N   . ASP A 1 80  ? 17.782 -17.972 47.947 1.000 52.040  0 80  ASP A N   1 ? 
ATOM   650  C CA  . ASP A 1 80  ? 17.251 -19.239 48.432 1.000 54.028  0 80  ASP A CA  1 ? 
ATOM   651  C C   . ASP A 1 80  ? 16.759 -20.091 47.268 1.000 47.922  0 80  ASP A C   1 ? 
ATOM   652  O O   . ASP A 1 80  ? 16.909 -21.301 47.286 1.000 55.421  0 80  ASP A O   1 ? 
ATOM   653  C CB  . ASP A 1 80  ? 16.168 -19.020 49.475 1.000 63.717  0 80  ASP A CB  1 ? 
ATOM   654  C CG  . ASP A 1 80  ? 16.615 -18.194 50.674 1.000 56.792  0 80  ASP A CG  1 ? 
ATOM   655  O OD1 . ASP A 1 80  ? 17.528 -18.650 51.374 1.000 55.043  0 80  ASP A OD1 1 ? 
ATOM   656  O OD2 . ASP A 1 80  ? 16.105 -17.064 50.835 1.000 51.503  0 80  ASP A OD2 1 ? 
ATOM   657  N N   . ILE A 1 81  ? 16.126 -19.461 46.280 1.000 49.435  0 81  ILE A N   1 ? 
ATOM   658  C CA  . ILE A 1 81  ? 15.305 -20.198 45.340 1.000 49.309  0 81  ILE A CA  1 ? 
ATOM   659  C C   . ILE A 1 81  ? 15.563 -19.699 43.922 1.000 44.063  0 81  ILE A C   1 ? 
ATOM   660  O O   . ILE A 1 81  ? 15.756 -18.514 43.713 1.000 46.282  0 81  ILE A O   1 ? 
ATOM   661  C CB  . ILE A 1 81  ? 13.828 -20.128 45.771 1.000 53.377  0 81  ILE A CB  1 ? 
ATOM   662  C CG1 . ILE A 1 81  ? 13.634 -21.126 46.923 1.000 60.010  0 81  ILE A CG1 1 ? 
ATOM   663  C CG2 . ILE A 1 81  ? 12.883 -20.439 44.600 1.000 53.262  0 81  ILE A CG2 1 ? 
ATOM   664  C CD1 . ILE A 1 81  ? 12.314 -21.035 47.613 1.000 56.247  0 81  ILE A CD1 1 ? 
ATOM   665  N N   . MET A 1 82  ? 15.623 -20.654 42.992 1.000 40.236  0 82  MET A N   1 ? 
ATOM   666  C CA  . MET A 1 82  ? 15.832 -20.398 41.579 1.000 49.732  0 82  MET A CA  1 ? 
ATOM   667  C C   . MET A 1 82  ? 14.495 -20.449 40.856 1.000 47.302  0 82  MET A C   1 ? 
ATOM   668  O O   . MET A 1 82  ? 13.827 -21.482 40.845 1.000 49.450  0 82  MET A O   1 ? 
ATOM   669  C CB  . MET A 1 82  ? 16.706 -21.484 40.943 1.000 48.293  0 82  MET A CB  1 ? 
ATOM   670  C CG  . MET A 1 82  ? 16.848 -21.368 39.427 1.000 49.716  0 82  MET A CG  1 ? 
ATOM   671  S SD  . MET A 1 82  ? 17.833 -19.927 38.990 1.000 53.434  0 82  MET A SD  1 ? 
ATOM   672  C CE  . MET A 1 82  ? 17.405 -19.797 37.260 1.000 55.413  0 82  MET A CE  1 ? 
ATOM   673  N N   . LEU A 1 83  ? 14.164 -19.329 40.227 1.000 51.869  0 83  LEU A N   1 ? 
ATOM   674  C CA  . LEU A 1 83  ? 12.938 -19.190 39.473 1.000 57.423  0 83  LEU A CA  1 ? 
ATOM   675  C C   . LEU A 1 83  ? 13.292 -19.110 37.994 1.000 55.351  0 83  LEU A C   1 ? 
ATOM   676  O O   . LEU A 1 83  ? 14.239 -18.415 37.623 1.000 50.397  0 83  LEU A O   1 ? 
ATOM   677  C CB  . LEU A 1 83  ? 12.235 -17.912 39.926 1.000 60.372  0 83  LEU A CB  1 ? 
ATOM   678  C CG  . LEU A 1 83  ? 10.805 -17.743 39.417 1.000 75.908  0 83  LEU A CG  1 ? 
ATOM   679  C CD1 . LEU A 1 83  ? 9.925  -18.832 40.050 1.000 81.832  0 83  LEU A CD1 1 ? 
ATOM   680  C CD2 . LEU A 1 83  ? 10.265 -16.348 39.695 1.000 68.596  0 83  LEU A CD2 1 ? 
ATOM   681  N N   . GLY A 1 84  ? 12.501 -19.802 37.176 1.000 47.972  0 84  GLY A N   1 ? 
ATOM   682  C CA  . GLY A 1 84  ? 12.629 -19.739 35.736 1.000 53.280  0 84  GLY A CA  1 ? 
ATOM   683  C C   . GLY A 1 84  ? 11.297 -19.461 35.046 1.000 51.764  0 84  GLY A C   1 ? 
ATOM   684  O O   . GLY A 1 84  ? 10.505 -20.383 34.823 1.000 52.562  0 84  GLY A O   1 ? 
ATOM   685  N N   . VAL A 1 85  ? 11.082 -18.195 34.681 1.000 49.926  0 85  VAL A N   1 ? 
ATOM   686  C CA  . VAL A 1 85  ? 9.981  -17.822 33.812 1.000 53.867  0 85  VAL A CA  1 ? 
ATOM   687  C C   . VAL A 1 85  ? 10.252 -18.396 32.428 1.000 55.327  0 85  VAL A C   1 ? 
ATOM   688  O O   . VAL A 1 85  ? 11.264 -18.058 31.835 1.000 56.865  0 85  VAL A O   1 ? 
ATOM   689  C CB  . VAL A 1 85  ? 9.817  -16.297 33.752 1.000 54.433  0 85  VAL A CB  1 ? 
ATOM   690  C CG1 . VAL A 1 85  ? 8.629  -15.906 32.873 1.000 55.669  0 85  VAL A CG1 1 ? 
ATOM   691  C CG2 . VAL A 1 85  ? 9.681  -15.701 35.148 1.000 54.379  0 85  VAL A CG2 1 ? 
ATOM   692  N N   . TYR A 1 86  ? 9.350  -19.255 31.938 1.000 49.723  0 86  TYR A N   1 ? 
ATOM   693  C CA  . TYR A 1 86  ? 9.651  -20.174 30.852 1.000 57.090  0 86  TYR A CA  1 ? 
ATOM   694  C C   . TYR A 1 86  ? 8.547  -20.159 29.781 1.000 60.192  0 86  TYR A C   1 ? 
ATOM   695  O O   . TYR A 1 86  ? 7.386  -20.471 30.066 1.000 59.179  0 86  TYR A O   1 ? 
ATOM   696  C CB  . TYR A 1 86  ? 9.757  -21.559 31.505 1.000 53.905  0 86  TYR A CB  1 ? 
ATOM   697  C CG  . TYR A 1 86  ? 10.513 -22.586 30.683 1.000 54.921  0 86  TYR A CG  1 ? 
ATOM   698  C CD1 . TYR A 1 86  ? 9.877  -23.341 29.710 1.000 57.814  0 86  TYR A CD1 1 ? 
ATOM   699  C CD2 . TYR A 1 86  ? 11.864 -22.816 30.906 1.000 53.577  0 86  TYR A CD2 1 ? 
ATOM   700  C CE1 . TYR A 1 86  ? 10.580 -24.254 28.938 1.000 56.569  0 86  TYR A CE1 1 ? 
ATOM   701  C CE2 . TYR A 1 86  ? 12.579 -23.716 30.136 1.000 58.586  0 86  TYR A CE2 1 ? 
ATOM   702  C CZ  . TYR A 1 86  ? 11.933 -24.441 29.153 1.000 58.439  0 86  TYR A CZ  1 ? 
ATOM   703  O OH  . TYR A 1 86  ? 12.663 -25.365 28.471 1.000 52.280  0 86  TYR A OH  1 ? 
ATOM   704  N N   . ILE A 1 87  ? 8.930  -19.834 28.538 1.000 54.206  0 87  ILE A N   1 ? 
ATOM   705  C CA  . ILE A 1 87  ? 8.041  -19.887 27.386 1.000 53.904  0 87  ILE A CA  1 ? 
ATOM   706  C C   . ILE A 1 87  ? 8.367  -21.137 26.585 1.000 54.499  0 87  ILE A C   1 ? 
ATOM   707  O O   . ILE A 1 87  ? 9.427  -21.226 25.974 1.000 63.424  0 87  ILE A O   1 ? 
ATOM   708  C CB  . ILE A 1 87  ? 8.125  -18.605 26.537 1.000 61.613  0 87  ILE A CB  1 ? 
ATOM   709  C CG1 . ILE A 1 87  ? 7.575  -17.384 27.257 1.000 68.625  0 87  ILE A CG1 1 ? 
ATOM   710  C CG2 . ILE A 1 87  ? 7.329  -18.797 25.254 1.000 67.308  0 87  ILE A CG2 1 ? 
ATOM   711  C CD1 . ILE A 1 87  ? 8.262  -17.031 28.551 1.000 90.620  0 87  ILE A CD1 1 ? 
ATOM   712  N N   . PRO A 1 88  ? 7.495  -22.170 26.593 1.000 52.415  0 88  PRO A N   1 ? 
ATOM   713  C CA  . PRO A 1 88  ? 7.747  -23.419 25.861 1.000 59.772  0 88  PRO A CA  1 ? 
ATOM   714  C C   . PRO A 1 88  ? 8.166  -23.330 24.390 1.000 58.091  0 88  PRO A C   1 ? 
ATOM   715  O O   . PRO A 1 88  ? 8.879  -24.205 23.920 1.000 61.947  0 88  PRO A O   1 ? 
ATOM   716  C CB  . PRO A 1 88  ? 6.380  -24.131 25.993 1.000 59.194  0 88  PRO A CB  1 ? 
ATOM   717  C CG  . PRO A 1 88  ? 5.873  -23.662 27.316 1.000 60.060  0 88  PRO A CG  1 ? 
ATOM   718  C CD  . PRO A 1 88  ? 6.234  -22.190 27.340 1.000 54.152  0 88  PRO A CD  1 ? 
ATOM   719  N N   . ASP A 1 89  ? 7.688  -22.298 23.684 1.000 62.312  0 89  ASP A N   1 ? 
ATOM   720  C CA  . ASP A 1 89  ? 7.941  -22.101 22.266 1.000 70.787  0 89  ASP A CA  1 ? 
ATOM   721  C C   . ASP A 1 89  ? 9.149  -21.195 22.057 1.000 65.322  0 89  ASP A C   1 ? 
ATOM   722  O O   . ASP A 1 89  ? 9.612  -21.078 20.933 1.000 56.833  0 89  ASP A O   1 ? 
ATOM   723  C CB  . ASP A 1 89  ? 6.839  -21.305 21.570 1.000 78.309  0 89  ASP A CB  1 ? 
ATOM   724  C CG  . ASP A 1 89  ? 5.411  -21.819 21.675 1.000 79.149  0 89  ASP A CG  1 ? 
ATOM   725  O OD1 . ASP A 1 89  ? 5.093  -22.787 20.971 1.000 87.121  0 89  ASP A OD1 1 ? 
ATOM   726  O OD2 . ASP A 1 89  ? 4.622  -21.234 22.450 1.000 87.276  0 89  ASP A OD2 1 ? 
ATOM   727  N N   . GLU A 1 90  ? 9.604  -20.520 23.118 1.000 61.504  0 90  GLU A N   1 ? 
ATOM   728  C CA  . GLU A 1 90  ? 10.696 -19.562 23.039 1.000 60.844  0 90  GLU A CA  1 ? 
ATOM   729  C C   . GLU A 1 90  ? 11.661 -19.800 24.203 1.000 61.893  0 90  GLU A C   1 ? 
ATOM   730  O O   . GLU A 1 90  ? 11.927 -18.934 25.043 1.000 59.945  0 90  GLU A O   1 ? 
ATOM   731  C CB  . GLU A 1 90  ? 10.149 -18.134 23.066 1.000 62.172  0 90  GLU A CB  1 ? 
ATOM   732  C CG  . GLU A 1 90  ? 9.181  -17.774 21.938 1.000 63.625  0 90  GLU A CG  1 ? 
ATOM   733  C CD  . GLU A 1 90  ? 8.679  -16.326 22.026 1.000 64.099  0 90  GLU A CD  1 ? 
ATOM   734  O OE1 . GLU A 1 90  ? 8.023  -15.870 21.069 1.000 74.906  0 90  GLU A OE1 1 ? 
ATOM   735  O OE2 . GLU A 1 90  ? 8.943  -15.628 23.026 1.000 64.784  0 90  GLU A OE2 1 ? 
ATOM   736  N N   . GLU A 1 91  ? 12.200 -21.011 24.253 1.000 57.919  0 91  GLU A N   1 ? 
ATOM   737  C CA  . GLU A 1 91  ? 13.097 -21.382 25.334 1.000 56.482  0 91  GLU A CA  1 ? 
ATOM   738  C C   . GLU A 1 91  ? 14.417 -20.621 25.222 1.000 58.821  0 91  GLU A C   1 ? 
ATOM   739  O O   . GLU A 1 91  ? 14.840 -20.253 24.129 1.000 57.692  0 91  GLU A O   1 ? 
ATOM   740  C CB  . GLU A 1 91  ? 13.210 -22.896 25.246 1.000 58.775  0 91  GLU A CB  1 ? 
ATOM   741  C CG  . GLU A 1 91  ? 11.873 -23.593 25.493 1.000 59.455  0 91  GLU A CG  1 ? 
ATOM   742  C CD  . GLU A 1 91  ? 11.913 -25.082 25.272 1.000 62.374  0 91  GLU A CD  1 ? 
ATOM   743  O OE1 . GLU A 1 91  ? 12.184 -25.414 24.103 1.000 56.919  0 91  GLU A OE1 1 ? 
ATOM   744  O OE2 . GLU A 1 91  ? 11.674 -25.887 26.214 1.000 58.021  0 91  GLU A OE2 1 ? 
ATOM   745  N N   . ASP A 1 92  ? 15.080 -20.406 26.360 1.000 61.218  0 92  ASP A N   1 ? 
ATOM   746  C CA  . ASP A 1 92  ? 16.272 -19.569 26.426 1.000 54.864  0 92  ASP A CA  1 ? 
ATOM   747  C C   . ASP A 1 92  ? 17.491 -20.335 26.946 1.000 56.627  0 92  ASP A C   1 ? 
ATOM   748  O O   . ASP A 1 92  ? 17.489 -20.904 28.047 1.000 55.434  0 92  ASP A O   1 ? 
ATOM   749  C CB  . ASP A 1 92  ? 16.022 -18.367 27.311 1.000 54.839  0 92  ASP A CB  1 ? 
ATOM   750  C CG  . ASP A 1 92  ? 17.130 -17.326 27.303 1.000 62.565  0 92  ASP A CG  1 ? 
ATOM   751  O OD1 . ASP A 1 92  ? 17.109 -16.454 26.405 1.000 69.244  0 92  ASP A OD1 1 ? 
ATOM   752  O OD2 . ASP A 1 92  ? 17.977 -17.379 28.220 1.000 64.273  0 92  ASP A OD2 1 ? 
ATOM   753  N N   . VAL A 1 93  ? 18.564 -20.290 26.153 1.000 48.034  0 93  VAL A N   1 ? 
ATOM   754  C CA  . VAL A 1 93  ? 19.818 -20.961 26.444 1.000 53.505  0 93  VAL A CA  1 ? 
ATOM   755  C C   . VAL A 1 93  ? 20.435 -20.452 27.749 1.000 48.834  0 93  VAL A C   1 ? 
ATOM   756  O O   . VAL A 1 93  ? 21.053 -21.226 28.479 1.000 49.660  0 93  VAL A O   1 ? 
ATOM   757  C CB  . VAL A 1 93  ? 20.823 -20.789 25.283 1.000 58.764  0 93  VAL A CB  1 ? 
ATOM   758  C CG1 . VAL A 1 93  ? 21.222 -19.332 25.086 1.000 61.291  0 93  VAL A CG1 1 ? 
ATOM   759  C CG2 . VAL A 1 93  ? 22.065 -21.653 25.479 1.000 60.123  0 93  VAL A CG2 1 ? 
ATOM   760  N N   . GLY A 1 94  ? 20.314 -19.150 28.012 1.000 52.629  0 94  GLY A N   1 ? 
ATOM   761  C CA  . GLY A 1 94  ? 20.901 -18.532 29.198 1.000 56.957  0 94  GLY A CA  1 ? 
ATOM   762  C C   . GLY A 1 94  ? 20.249 -19.061 30.469 1.000 58.999  0 94  GLY A C   1 ? 
ATOM   763  O O   . GLY A 1 94  ? 20.943 -19.446 31.411 1.000 49.792  0 94  GLY A O   1 ? 
ATOM   764  N N   . LEU A 1 95  ? 18.912 -19.136 30.433 1.000 54.186  0 95  LEU A N   1 ? 
ATOM   765  C CA  . LEU A 1 95  ? 18.138 -19.702 31.524 1.000 52.650  0 95  LEU A CA  1 ? 
ATOM   766  C C   . LEU A 1 95  ? 18.509 -21.169 31.717 1.000 48.272  0 95  LEU A C   1 ? 
ATOM   767  O O   . LEU A 1 95  ? 18.681 -21.625 32.837 1.000 56.863  0 95  LEU A O   1 ? 
ATOM   768  C CB  . LEU A 1 95  ? 16.640 -19.558 31.230 1.000 53.828  0 95  LEU A CB  1 ? 
ATOM   769  C CG  . LEU A 1 95  ? 15.695 -20.030 32.339 1.000 57.012  0 95  LEU A CG  1 ? 
ATOM   770  C CD1 . LEU A 1 95  ? 16.109 -19.423 33.690 1.000 51.197  0 95  LEU A CD1 1 ? 
ATOM   771  C CD2 . LEU A 1 95  ? 14.223 -19.738 32.016 1.000 55.909  0 95  LEU A CD2 1 ? 
ATOM   772  N N   . GLY A 1 96  ? 18.584 -21.922 30.624 1.000 50.300  0 96  GLY A N   1 ? 
ATOM   773  C CA  . GLY A 1 96  ? 19.030 -23.304 30.681 1.000 51.586  0 96  GLY A CA  1 ? 
ATOM   774  C C   . GLY A 1 96  ? 20.317 -23.433 31.496 1.000 57.667  0 96  GLY A C   1 ? 
ATOM   775  O O   . GLY A 1 96  ? 20.372 -24.234 32.430 1.000 47.231  0 96  GLY A O   1 ? 
ATOM   776  N N   . MET A 1 97  ? 21.331 -22.619 31.152 1.000 54.991  0 97  MET A N   1 ? 
ATOM   777  C CA  . MET A 1 97  ? 22.609 -22.673 31.843 1.000 49.741  0 97  MET A CA  1 ? 
ATOM   778  C C   . MET A 1 97  ? 22.380 -22.385 33.329 1.000 50.952  0 97  MET A C   1 ? 
ATOM   779  O O   . MET A 1 97  ? 22.866 -23.107 34.193 1.000 49.638  0 97  MET A O   1 ? 
ATOM   780  C CB  . MET A 1 97  ? 23.605 -21.686 31.214 1.000 47.326  0 97  MET A CB  1 ? 
ATOM   781  C CG  . MET A 1 97  ? 25.001 -21.672 31.855 1.000 52.247  0 97  MET A CG  1 ? 
ATOM   782  S SD  . MET A 1 97  ? 25.047 -20.674 33.358 1.000 51.967  0 97  MET A SD  1 ? 
ATOM   783  C CE  . MET A 1 97  ? 26.418 -21.343 34.300 1.000 54.547  0 97  MET A CE  1 ? 
ATOM   784  N N   . GLU A 1 98  ? 21.604 -21.339 33.620 1.000 53.723  0 98  GLU A N   1 ? 
ATOM   785  C CA  . GLU A 1 98  ? 21.349 -20.904 34.983 1.000 49.644  0 98  GLU A CA  1 ? 
ATOM   786  C C   . GLU A 1 98  ? 20.632 -21.997 35.765 1.000 49.544  0 98  GLU A C   1 ? 
ATOM   787  O O   . GLU A 1 98  ? 20.927 -22.211 36.951 1.000 50.581  0 98  GLU A O   1 ? 
ATOM   788  C CB  . GLU A 1 98  ? 20.548 -19.604 34.992 1.000 48.554  0 98  GLU A CB  1 ? 
ATOM   789  C CG  . GLU A 1 98  ? 21.348 -18.389 34.520 1.000 53.735  0 98  GLU A CG  1 ? 
ATOM   790  C CD  . GLU A 1 98  ? 20.531 -17.291 33.850 1.000 59.863  0 98  GLU A CD  1 ? 
ATOM   791  O OE1 . GLU A 1 98  ? 19.280 -17.419 33.812 1.000 53.736  0 98  GLU A OE1 1 ? 
ATOM   792  O OE2 . GLU A 1 98  ? 21.135 -16.308 33.338 1.000 57.303  0 98  GLU A OE2 1 ? 
ATOM   793  N N   . LEU A 1 99  ? 19.705 -22.705 35.107 1.000 54.114  0 99  LEU A N   1 ? 
ATOM   794  C CA  . LEU A 1 99  ? 19.031 -23.823 35.767 1.000 50.692  0 99  LEU A CA  1 ? 
ATOM   795  C C   . LEU A 1 99  ? 20.068 -24.853 36.214 1.000 56.584  0 99  LEU A C   1 ? 
ATOM   796  O O   . LEU A 1 99  ? 20.051 -25.313 37.354 1.000 56.971  0 99  LEU A O   1 ? 
ATOM   797  C CB  . LEU A 1 99  ? 17.968 -24.436 34.865 1.000 48.048  0 99  LEU A CB  1 ? 
ATOM   798  C CG  . LEU A 1 99  ? 16.796 -23.513 34.499 1.000 50.715  0 99  LEU A CG  1 ? 
ATOM   799  C CD1 . LEU A 1 99  ? 15.856 -24.159 33.495 1.000 53.401  0 99  LEU A CD1 1 ? 
ATOM   800  C CD2 . LEU A 1 99  ? 15.996 -23.106 35.712 1.000 50.055  0 99  LEU A CD2 1 ? 
ATOM   801  N N   . GLY A 1 100 ? 20.985 -25.202 35.304 1.000 54.300  0 100 GLY A N   1 ? 
ATOM   802  C CA  . GLY A 1 100 ? 22.041 -26.165 35.576 1.000 53.703  0 100 GLY A CA  1 ? 
ATOM   803  C C   . GLY A 1 100 ? 22.954 -25.707 36.713 1.000 46.958  0 100 GLY A C   1 ? 
ATOM   804  O O   . GLY A 1 100 ? 23.329 -26.504 37.539 1.000 44.821  0 100 GLY A O   1 ? 
ATOM   805  N N   . TYR A 1 101 ? 23.236 -24.404 36.795 1.000 44.913  0 101 TYR A N   1 ? 
ATOM   806  C CA  . TYR A 1 101 ? 24.054 -23.870 37.863 1.000 49.769  0 101 TYR A CA  1 ? 
ATOM   807  C C   . TYR A 1 101 ? 23.291 -23.961 39.182 1.000 52.113  0 101 TYR A C   1 ? 
ATOM   808  O O   . TYR A 1 101 ? 23.849 -24.402 40.189 1.000 52.276  0 101 TYR A O   1 ? 
ATOM   809  C CB  . TYR A 1 101 ? 24.527 -22.467 37.466 1.000 49.724  0 101 TYR A CB  1 ? 
ATOM   810  C CG  . TYR A 1 101 ? 25.438 -21.862 38.517 1.000 49.773  0 101 TYR A CG  1 ? 
ATOM   811  C CD1 . TYR A 1 101 ? 26.778 -22.228 38.635 1.000 56.971  0 101 TYR A CD1 1 ? 
ATOM   812  C CD2 . TYR A 1 101 ? 24.925 -20.982 39.449 1.000 54.435  0 101 TYR A CD2 1 ? 
ATOM   813  C CE1 . TYR A 1 101 ? 27.594 -21.686 39.619 1.000 47.888  0 101 TYR A CE1 1 ? 
ATOM   814  C CE2 . TYR A 1 101 ? 25.712 -20.478 40.467 1.000 52.930  0 101 TYR A CE2 1 ? 
ATOM   815  C CZ  . TYR A 1 101 ? 27.046 -20.820 40.552 1.000 52.967  0 101 TYR A CZ  1 ? 
ATOM   816  O OH  . TYR A 1 101 ? 27.741 -20.236 41.575 1.000 57.460  0 101 TYR A OH  1 ? 
ATOM   817  N N   . ALA A 1 102 ? 22.012 -23.565 39.152 1.000 51.176  0 102 ALA A N   1 ? 
ATOM   818  C CA  . ALA A 1 102 ? 21.151 -23.641 40.327 1.000 52.615  0 102 ALA A CA  1 ? 
ATOM   819  C C   . ALA A 1 102 ? 21.109 -25.066 40.892 1.000 52.180  0 102 ALA A C   1 ? 
ATOM   820  O O   . ALA A 1 102 ? 21.177 -25.235 42.094 1.000 49.741  0 102 ALA A O   1 ? 
ATOM   821  C CB  . ALA A 1 102 ? 19.761 -23.143 39.991 1.000 53.922  0 102 ALA A CB  1 ? 
ATOM   822  N N   . LEU A 1 103 ? 21.003 -26.088 40.038 1.000 55.519  0 103 LEU A N   1 ? 
ATOM   823  C CA  . LEU A 1 103 ? 21.063 -27.476 40.468 1.000 56.122  0 103 LEU A CA  1 ? 
ATOM   824  C C   . LEU A 1 103 ? 22.394 -27.735 41.162 1.000 52.183  0 103 LEU A C   1 ? 
ATOM   825  O O   . LEU A 1 103 ? 22.442 -28.311 42.238 1.000 57.565  0 103 LEU A O   1 ? 
ATOM   826  C CB  . LEU A 1 103 ? 20.908 -28.459 39.312 1.000 58.802  0 103 LEU A CB  1 ? 
ATOM   827  C CG  . LEU A 1 103 ? 21.119 -29.948 39.646 1.000 62.462  0 103 LEU A CG  1 ? 
ATOM   828  C CD1 . LEU A 1 103 ? 20.000 -30.598 40.482 1.000 56.755  0 103 LEU A CD1 1 ? 
ATOM   829  C CD2 . LEU A 1 103 ? 21.281 -30.736 38.338 1.000 58.079  0 103 LEU A CD2 1 ? 
ATOM   830  N N   . SER A 1 104 ? 23.485 -27.315 40.544 1.000 57.453  0 104 SER A N   1 ? 
ATOM   831  C CA  . SER A 1 104 ? 24.799 -27.547 41.128 1.000 60.137  0 104 SER A CA  1 ? 
ATOM   832  C C   . SER A 1 104 ? 24.906 -26.896 42.513 1.000 58.202  0 104 SER A C   1 ? 
ATOM   833  O O   . SER A 1 104 ? 25.710 -27.311 43.329 1.000 52.009  0 104 SER A O   1 ? 
ATOM   834  C CB  . SER A 1 104 ? 25.893 -27.035 40.219 1.000 55.773  0 104 SER A CB  1 ? 
ATOM   835  O OG  . SER A 1 104 ? 26.171 -25.646 40.408 1.000 59.975  0 104 SER A OG  1 ? 
ATOM   836  N N   . GLN A 1 105 ? 24.145 -25.819 42.760 1.000 55.143  0 105 GLN A N   1 ? 
ATOM   837  C CA  . GLN A 1 105 ? 24.246 -25.102 44.024 1.000 51.310  0 105 GLN A CA  1 ? 
ATOM   838  C C   . GLN A 1 105 ? 23.173 -25.538 45.012 1.000 51.739  0 105 GLN A C   1 ? 
ATOM   839  O O   . GLN A 1 105 ? 23.004 -24.888 46.030 1.000 47.560  0 105 GLN A O   1 ? 
ATOM   840  C CB  . GLN A 1 105 ? 24.093 -23.593 43.815 1.000 57.590  0 105 GLN A CB  1 ? 
ATOM   841  C CG  . GLN A 1 105 ? 25.223 -22.967 43.017 1.000 50.985  0 105 GLN A CG  1 ? 
ATOM   842  C CD  . GLN A 1 105 ? 26.563 -23.125 43.699 1.000 56.631  0 105 GLN A CD  1 ? 
ATOM   843  O OE1 . GLN A 1 105 ? 26.724 -22.744 44.849 1.000 53.640  0 105 GLN A OE1 1 ? 
ATOM   844  N NE2 . GLN A 1 105 ? 27.544 -23.662 42.995 1.000 59.826  0 105 GLN A NE2 1 ? 
ATOM   845  N N   . GLY A 1 106 ? 22.415 -26.605 44.722 1.000 46.888  0 106 GLY A N   1 ? 
ATOM   846  C CA  . GLY A 1 106 ? 21.506 -27.127 45.726 1.000 50.065  0 106 GLY A CA  1 ? 
ATOM   847  C C   . GLY A 1 106 ? 20.209 -26.332 45.879 1.000 48.245  0 106 GLY A C   1 ? 
ATOM   848  O O   . GLY A 1 106 ? 19.545 -26.468 46.889 1.000 51.833  0 106 GLY A O   1 ? 
ATOM   849  N N   . LYS A 1 107 ? 19.830 -25.532 44.877 1.000 48.127  0 107 LYS A N   1 ? 
ATOM   850  C CA  . LYS A 1 107 ? 18.658 -24.677 44.957 1.000 46.190  0 107 LYS A CA  1 ? 
ATOM   851  C C   . LYS A 1 107 ? 17.412 -25.353 44.410 1.000 49.228  0 107 LYS A C   1 ? 
ATOM   852  O O   . LYS A 1 107 ? 17.460 -26.063 43.407 1.000 50.077  0 107 LYS A O   1 ? 
ATOM   853  C CB  . LYS A 1 107 ? 18.811 -23.423 44.092 1.000 49.843  0 107 LYS A CB  1 ? 
ATOM   854  C CG  . LYS A 1 107 ? 20.059 -22.613 44.379 1.000 47.049  0 107 LYS A CG  1 ? 
ATOM   855  C CD  . LYS A 1 107 ? 20.127 -22.122 45.810 1.000 47.052  0 107 LYS A CD  1 ? 
ATOM   856  C CE  . LYS A 1 107 ? 21.457 -21.470 46.053 1.000 49.151  0 107 LYS A CE  1 ? 
ATOM   857  N NZ  . LYS A 1 107 ? 21.507 -20.857 47.376 1.000 47.806  0 107 LYS A NZ  1 ? 
ATOM   858  N N   . TYR A 1 108 ? 16.278 -25.070 45.060 1.000 53.031  0 108 TYR A N   1 ? 
ATOM   859  C CA  . TYR A 1 108 ? 14.976 -25.449 44.539 1.000 52.533  0 108 TYR A CA  1 ? 
ATOM   860  C C   . TYR A 1 108 ? 14.778 -24.729 43.212 1.000 50.367  0 108 TYR A C   1 ? 
ATOM   861  O O   . TYR A 1 108 ? 15.004 -23.529 43.117 1.000 49.542  0 108 TYR A O   1 ? 
ATOM   862  C CB  . TYR A 1 108 ? 13.844 -25.071 45.500 1.000 51.929  0 108 TYR A CB  1 ? 
ATOM   863  C CG  . TYR A 1 108 ? 12.449 -25.541 45.102 1.000 48.990  0 108 TYR A CG  1 ? 
ATOM   864  C CD1 . TYR A 1 108 ? 12.110 -26.884 45.158 1.000 50.603  0 108 TYR A CD1 1 ? 
ATOM   865  C CD2 . TYR A 1 108 ? 11.459 -24.638 44.714 1.000 49.685  0 108 TYR A CD2 1 ? 
ATOM   866  C CE1 . TYR A 1 108 ? 10.824 -27.316 44.873 1.000 54.962  0 108 TYR A CE1 1 ? 
ATOM   867  C CE2 . TYR A 1 108 ? 10.171 -25.064 44.397 1.000 52.336  0 108 TYR A CE2 1 ? 
ATOM   868  C CZ  . TYR A 1 108 ? 9.849  -26.405 44.493 1.000 45.374  0 108 TYR A CZ  1 ? 
ATOM   869  O OH  . TYR A 1 108 ? 8.598  -26.860 44.207 1.000 47.103  0 108 TYR A OH  1 ? 
ATOM   870  N N   . VAL A 1 109 ? 14.417 -25.493 42.184 1.000 50.921  0 109 VAL A N   1 ? 
ATOM   871  C CA  . VAL A 1 109 ? 14.302 -24.959 40.839 1.000 51.559  0 109 VAL A CA  1 ? 
ATOM   872  C C   . VAL A 1 109 ? 12.831 -25.025 40.448 1.000 47.476  0 109 VAL A C   1 ? 
ATOM   873  O O   . VAL A 1 109 ? 12.312 -26.111 40.243 1.000 49.570  0 109 VAL A O   1 ? 
ATOM   874  C CB  . VAL A 1 109 ? 15.170 -25.735 39.833 1.000 47.056  0 109 VAL A CB  1 ? 
ATOM   875  C CG1 . VAL A 1 109 ? 14.960 -25.245 38.417 1.000 48.240  0 109 VAL A CG1 1 ? 
ATOM   876  C CG2 . VAL A 1 109 ? 16.645 -25.682 40.181 1.000 49.074  0 109 VAL A CG2 1 ? 
ATOM   877  N N   . LEU A 1 110 ? 12.202 -23.857 40.312 1.000 49.622  0 110 LEU A N   1 ? 
ATOM   878  C CA  . LEU A 1 110 ? 10.783 -23.736 40.021 1.000 53.344  0 110 LEU A CA  1 ? 
ATOM   879  C C   . LEU A 1 110 ? 10.647 -23.042 38.670 1.000 48.889  0 110 LEU A C   1 ? 
ATOM   880  O O   . LEU A 1 110 ? 11.117 -21.910 38.504 1.000 52.286  0 110 LEU A O   1 ? 
ATOM   881  C CB  . LEU A 1 110 ? 10.153 -22.870 41.114 1.000 48.076  0 110 LEU A CB  1 ? 
ATOM   882  C CG  . LEU A 1 110 ? 8.659  -23.028 41.422 1.000 56.667  0 110 LEU A CG  1 ? 
ATOM   883  C CD1 . LEU A 1 110 ? 8.063  -21.661 41.622 1.000 50.698  0 110 LEU A CD1 1 ? 
ATOM   884  C CD2 . LEU A 1 110 ? 7.788  -23.849 40.517 1.000 55.017  0 110 LEU A CD2 1 ? 
ATOM   885  N N   . LEU A 1 111 ? 10.020 -23.726 37.713 1.000 50.385  0 111 LEU A N   1 ? 
ATOM   886  C CA  . LEU A 1 111 ? 9.617  -23.081 36.468 1.000 58.304  0 111 LEU A CA  1 ? 
ATOM   887  C C   . LEU A 1 111 ? 8.189  -22.542 36.582 1.000 52.928  0 111 LEU A C   1 ? 
ATOM   888  O O   . LEU A 1 111 ? 7.323  -23.174 37.162 1.000 50.377  0 111 LEU A O   1 ? 
ATOM   889  C CB  . LEU A 1 111 ? 9.735  -24.059 35.306 1.000 56.472  0 111 LEU A CB  1 ? 
ATOM   890  C CG  . LEU A 1 111 ? 11.086 -24.760 35.106 1.000 55.881  0 111 LEU A CG  1 ? 
ATOM   891  C CD1 . LEU A 1 111 ? 10.991 -25.658 33.871 1.000 54.665  0 111 LEU A CD1 1 ? 
ATOM   892  C CD2 . LEU A 1 111 ? 12.231 -23.755 34.970 1.000 59.668  0 111 LEU A CD2 1 ? 
ATOM   893  N N   . VAL A 1 112 ? 7.953  -21.405 35.935 1.000 57.436  0 112 VAL A N   1 ? 
ATOM   894  C CA  . VAL A 1 112 ? 6.660  -20.745 35.855 1.000 59.581  0 112 VAL A CA  1 ? 
ATOM   895  C C   . VAL A 1 112 ? 6.353  -20.475 34.379 1.000 59.099  0 112 VAL A C   1 ? 
ATOM   896  O O   . VAL A 1 112 ? 7.052  -19.701 33.735 1.000 59.000  0 112 VAL A O   1 ? 
ATOM   897  C CB  . VAL A 1 112 ? 6.640  -19.405 36.623 1.000 61.049  0 112 VAL A CB  1 ? 
ATOM   898  C CG1 . VAL A 1 112 ? 5.217  -18.880 36.738 1.000 64.261  0 112 VAL A CG1 1 ? 
ATOM   899  C CG2 . VAL A 1 112 ? 7.253  -19.546 38.000 1.000 72.956  0 112 VAL A CG2 1 ? 
ATOM   900  N N   . ILE A 1 113 ? 5.245  -21.037 33.898 1.000 56.987  0 113 ILE A N   1 ? 
ATOM   901  C CA  . ILE A 1 113 ? 4.791  -20.939 32.526 1.000 47.565  0 113 ILE A CA  1 ? 
ATOM   902  C C   . ILE A 1 113 ? 3.478  -20.162 32.503 1.000 54.880  0 113 ILE A C   1 ? 
ATOM   903  O O   . ILE A 1 113 ? 2.567  -20.431 33.294 1.000 57.005  0 113 ILE A O   1 ? 
ATOM   904  C CB  . ILE A 1 113 ? 4.632  -22.355 31.960 1.000 53.362  0 113 ILE A CB  1 ? 
ATOM   905  C CG1 . ILE A 1 113 ? 5.959  -23.113 31.987 1.000 50.382  0 113 ILE A CG1 1 ? 
ATOM   906  C CG2 . ILE A 1 113 ? 4.025  -22.345 30.555 1.000 56.960  0 113 ILE A CG2 1 ? 
ATOM   907  C CD1 . ILE A 1 113 ? 5.809  -24.587 31.710 1.000 53.495  0 113 ILE A CD1 1 ? 
ATOM   908  N N   . PRO A 1 114 ? 3.324  -19.176 31.599 1.000 54.603  0 114 PRO A N   1 ? 
ATOM   909  C CA  . PRO A 1 114 ? 2.037  -18.507 31.392 1.000 55.386  0 114 PRO A CA  1 ? 
ATOM   910  C C   . PRO A 1 114 ? 0.893  -19.502 31.300 1.000 52.421  0 114 PRO A C   1 ? 
ATOM   911  O O   . PRO A 1 114 ? 1.063  -20.585 30.716 1.000 54.527  0 114 PRO A O   1 ? 
ATOM   912  C CB  . PRO A 1 114 ? 2.246  -17.750 30.067 1.000 59.498  0 114 PRO A CB  1 ? 
ATOM   913  C CG  . PRO A 1 114 ? 3.727  -17.421 30.112 1.000 58.351  0 114 PRO A CG  1 ? 
ATOM   914  C CD  . PRO A 1 114 ? 4.364  -18.678 30.688 1.000 57.391  0 114 PRO A CD  1 ? 
ATOM   915  N N   . ASP A 1 115 ? -0.262 -19.140 31.900 1.000 58.561  0 115 ASP A N   1 ? 
ATOM   916  C CA  . ASP A 1 115 ? -1.408 -20.044 31.946 1.000 67.381  0 115 ASP A CA  1 ? 
ATOM   917  C C   . ASP A 1 115 ? -1.774 -20.481 30.528 1.000 60.205  0 115 ASP A C   1 ? 
ATOM   918  O O   . ASP A 1 115 ? -2.093 -21.646 30.305 1.000 55.226  0 115 ASP A O   1 ? 
ATOM   919  C CB  . ASP A 1 115 ? -2.607 -19.452 32.676 1.000 63.563  0 115 ASP A CB  1 ? 
ATOM   920  C CG  . ASP A 1 115 ? -2.405 -19.156 34.156 1.000 68.227  0 115 ASP A CG  1 ? 
ATOM   921  O OD1 . ASP A 1 115 ? -1.461 -18.425 34.495 1.000 78.647  0 115 ASP A OD1 1 ? 
ATOM   922  O OD2 . ASP A 1 115 ? -3.195 -19.647 34.969 1.000 69.804  0 115 ASP A OD2 1 ? 
ATOM   923  N N   . GLU A 1 116 ? -1.699 -19.535 29.577 1.000 65.631  0 116 GLU A N   1 ? 
ATOM   924  C CA  . GLU A 1 116 ? -2.068 -19.801 28.190 1.000 67.886  0 116 GLU A CA  1 ? 
ATOM   925  C C   . GLU A 1 116 ? -1.129 -20.818 27.535 1.000 61.530  0 116 GLU A C   1 ? 
ATOM   926  O O   . GLU A 1 116 ? -1.502 -21.392 26.515 1.000 63.573  0 116 GLU A O   1 ? 
ATOM   927  C CB  . GLU A 1 116 ? -2.170 -18.539 27.323 1.000 69.128  0 116 GLU A CB  1 ? 
ATOM   928  C CG  . GLU A 1 116 ? -0.963 -17.600 27.389 1.000 80.727  0 116 GLU A CG  1 ? 
ATOM   929  C CD  . GLU A 1 116 ? -0.944 -16.567 28.523 1.000 84.865  0 116 GLU A CD  1 ? 
ATOM   930  O OE1 . GLU A 1 116 ? -1.297 -16.902 29.697 1.000 61.392  0 116 GLU A OE1 1 ? 
ATOM   931  O OE2 . GLU A 1 116 ? -0.547 -15.407 28.232 1.000 81.153  0 116 GLU A OE2 1 ? 
ATOM   932  N N   . ASP A 1 117 ? 0.076  -21.051 28.091 1.000 59.647  0 117 ASP A N   1 ? 
ATOM   933  C CA  . ASP A 1 117 ? 1.023  -22.005 27.509 1.000 58.595  0 117 ASP A CA  1 ? 
ATOM   934  C C   . ASP A 1 117 ? 1.195  -23.275 28.349 1.000 54.536  0 117 ASP A C   1 ? 
ATOM   935  O O   . ASP A 1 117 ? 1.817  -24.240 27.881 1.000 53.455  0 117 ASP A O   1 ? 
ATOM   936  C CB  . ASP A 1 117 ? 2.378  -21.362 27.244 1.000 65.066  0 117 ASP A CB  1 ? 
ATOM   937  C CG  . ASP A 1 117 ? 2.379  -20.168 26.297 1.000 66.211  0 117 ASP A CG  1 ? 
ATOM   938  O OD1 . ASP A 1 117 ? 1.638  -20.212 25.291 1.000 67.514  0 117 ASP A OD1 1 ? 
ATOM   939  O OD2 . ASP A 1 117 ? 3.142  -19.211 26.546 1.000 63.454  0 117 ASP A OD2 1 ? 
ATOM   940  N N   . TYR A 1 118 ? 0.683  -23.287 29.592 1.000 55.576  0 118 TYR A N   1 ? 
ATOM   941  C CA  . TYR A 1 118 ? 0.906  -24.415 30.490 1.000 56.121  0 118 TYR A CA  1 ? 
ATOM   942  C C   . TYR A 1 118 ? 0.302  -25.673 29.870 1.000 61.901  0 118 TYR A C   1 ? 
ATOM   943  O O   . TYR A 1 118 ? -0.874 -25.673 29.502 1.000 58.834  0 118 TYR A O   1 ? 
ATOM   944  C CB  . TYR A 1 118 ? 0.298  -24.216 31.896 1.000 64.260  0 118 TYR A CB  1 ? 
ATOM   945  C CG  . TYR A 1 118 ? 0.734  -25.261 32.920 1.000 63.279  0 118 TYR A CG  1 ? 
ATOM   946  C CD1 . TYR A 1 118 ? 0.156  -26.524 32.973 1.000 63.392  0 118 TYR A CD1 1 ? 
ATOM   947  C CD2 . TYR A 1 118 ? 1.792  -25.006 33.779 1.000 64.306  0 118 TYR A CD2 1 ? 
ATOM   948  C CE1 . TYR A 1 118 ? 0.590  -27.487 33.878 1.000 65.846  0 118 TYR A CE1 1 ? 
ATOM   949  C CE2 . TYR A 1 118 ? 2.226  -25.953 34.693 1.000 62.806  0 118 TYR A CE2 1 ? 
ATOM   950  C CZ  . TYR A 1 118 ? 1.628  -27.195 34.747 1.000 67.762  0 118 TYR A CZ  1 ? 
ATOM   951  O OH  . TYR A 1 118 ? 2.127  -28.098 35.640 1.000 74.606  0 118 TYR A OH  1 ? 
ATOM   952  N N   . GLY A 1 119 ? 1.103  -26.746 29.798 1.000 62.258  0 119 GLY A N   1 ? 
ATOM   953  C CA  . GLY A 1 119 ? 0.707  -27.984 29.137 1.000 64.663  0 119 GLY A CA  1 ? 
ATOM   954  C C   . GLY A 1 119 ? 1.516  -28.246 27.867 1.000 58.573  0 119 GLY A C   1 ? 
ATOM   955  O O   . GLY A 1 119 ? 1.692  -29.399 27.472 1.000 60.141  0 119 GLY A O   1 ? 
ATOM   956  N N   . LYS A 1 120 ? 2.017  -27.176 27.241 1.000 61.229  0 120 LYS A N   1 ? 
ATOM   957  C CA  . LYS A 1 120 ? 2.753  -27.302 25.995 1.000 64.920  0 120 LYS A CA  1 ? 
ATOM   958  C C   . LYS A 1 120 ? 4.099  -27.986 26.240 1.000 70.730  0 120 LYS A C   1 ? 
ATOM   959  O O   . LYS A 1 120 ? 4.650  -27.951 27.344 1.000 59.149  0 120 LYS A O   1 ? 
ATOM   960  C CB  . LYS A 1 120 ? 2.937  -25.968 25.270 1.000 64.025  0 120 LYS A CB  1 ? 
ATOM   961  C CG  . LYS A 1 120 ? 1.630  -25.374 24.750 1.000 80.202  0 120 LYS A CG  1 ? 
ATOM   962  C CD  . LYS A 1 120 ? 1.786  -24.517 23.501 1.000 93.214  0 120 LYS A CD  1 ? 
ATOM   963  C CE  . LYS A 1 120 ? 2.142  -23.109 23.751 1.000 92.194  0 120 LYS A CE  1 ? 
ATOM   964  N NZ  . LYS A 1 120 ? 0.940  -22.277 23.725 1.000 82.280  0 120 LYS A NZ  1 ? 
ATOM   965  N N   . PRO A 1 121 ? 4.643  -28.694 25.223 1.000 62.515  0 121 PRO A N   1 ? 
ATOM   966  C CA  . PRO A 1 121 ? 5.870  -29.472 25.399 1.000 57.639  0 121 PRO A CA  1 ? 
ATOM   967  C C   . PRO A 1 121 ? 7.034  -28.594 25.837 1.000 60.159  0 121 PRO A C   1 ? 
ATOM   968  O O   . PRO A 1 121 ? 7.169  -27.474 25.344 1.000 60.191  0 121 PRO A O   1 ? 
ATOM   969  C CB  . PRO A 1 121 ? 6.091  -30.084 23.998 1.000 66.455  0 121 PRO A CB  1 ? 
ATOM   970  C CG  . PRO A 1 121 ? 4.698  -30.160 23.406 1.000 62.991  0 121 PRO A CG  1 ? 
ATOM   971  C CD  . PRO A 1 121 ? 4.044  -28.866 23.887 1.000 58.321  0 121 PRO A CD  1 ? 
ATOM   972  N N   . ILE A 1 122 ? 7.873  -29.102 26.766 1.000 52.686  0 122 ILE A N   1 ? 
ATOM   973  C CA  . ILE A 1 122 ? 9.110  -28.407 27.112 1.000 52.948  0 122 ILE A CA  1 ? 
ATOM   974  C C   . ILE A 1 122 ? 10.288 -29.339 26.909 1.000 48.441  0 122 ILE A C   1 ? 
ATOM   975  O O   . ILE A 1 122 ? 10.124 -30.551 26.938 1.000 52.683  0 122 ILE A O   1 ? 
ATOM   976  C CB  . ILE A 1 122 ? 9.077  -27.843 28.548 1.000 56.219  0 122 ILE A CB  1 ? 
ATOM   977  C CG1 . ILE A 1 122 ? 9.111  -28.952 29.599 1.000 52.060  0 122 ILE A CG1 1 ? 
ATOM   978  C CG2 . ILE A 1 122 ? 7.887  -26.896 28.751 1.000 51.609  0 122 ILE A CG2 1 ? 
ATOM   979  C CD1 . ILE A 1 122 ? 9.003  -28.443 31.021 1.000 57.651  0 122 ILE A CD1 1 ? 
ATOM   980  N N   . ASN A 1 123 ? 11.473 -28.760 26.704 1.000 52.632  0 123 ASN A N   1 ? 
ATOM   981  C CA  . ASN A 1 123 ? 12.692 -29.547 26.552 1.000 53.597  0 123 ASN A CA  1 ? 
ATOM   982  C C   . ASN A 1 123 ? 12.859 -30.496 27.724 1.000 53.754  0 123 ASN A C   1 ? 
ATOM   983  O O   . ASN A 1 123 ? 12.710 -30.102 28.875 1.000 57.262  0 123 ASN A O   1 ? 
ATOM   984  C CB  . ASN A 1 123 ? 13.929 -28.660 26.489 1.000 57.982  0 123 ASN A CB  1 ? 
ATOM   985  C CG  . ASN A 1 123 ? 15.130 -29.414 25.993 1.000 61.465  0 123 ASN A CG  1 ? 
ATOM   986  O OD1 . ASN A 1 123 ? 15.717 -30.195 26.751 1.000 61.397  0 123 ASN A OD1 1 ? 
ATOM   987  N ND2 . ASN A 1 123 ? 15.499 -29.193 24.737 1.000 65.380  0 123 ASN A ND2 1 ? 
ATOM   988  N N   . LEU A 1 124 ? 13.198 -31.744 27.400 1.000 57.057  0 124 LEU A N   1 ? 
ATOM   989  C CA  . LEU A 1 124 ? 13.433 -32.785 28.381 1.000 54.177  0 124 LEU A CA  1 ? 
ATOM   990  C C   . LEU A 1 124 ? 14.396 -32.340 29.486 1.000 57.984  0 124 LEU A C   1 ? 
ATOM   991  O O   . LEU A 1 124 ? 14.218 -32.727 30.633 1.000 56.272  0 124 LEU A O   1 ? 
ATOM   992  C CB  . LEU A 1 124 ? 13.969 -34.020 27.673 1.000 52.777  0 124 LEU A CB  1 ? 
ATOM   993  C CG  . LEU A 1 124 ? 14.357 -35.164 28.613 1.000 57.987  0 124 LEU A CG  1 ? 
ATOM   994  C CD1 . LEU A 1 124 ? 13.108 -35.713 29.313 1.000 52.354  0 124 LEU A CD1 1 ? 
ATOM   995  C CD2 . LEU A 1 124 ? 15.126 -36.253 27.911 1.000 57.762  0 124 LEU A CD2 1 ? 
ATOM   996  N N   . MET A 1 125 ? 15.445 -31.593 29.142 1.000 56.083  0 125 MET A N   1 ? 
ATOM   997  C CA  . MET A 1 125 ? 16.459 -31.274 30.126 1.000 51.959  0 125 MET A CA  1 ? 
ATOM   998  C C   . MET A 1 125 ? 15.905 -30.211 31.078 1.000 53.222  0 125 MET A C   1 ? 
ATOM   999  O O   . MET A 1 125 ? 16.302 -30.180 32.235 1.000 56.633  0 125 MET A O   1 ? 
ATOM   1000 C CB  . MET A 1 125 ? 17.771 -30.787 29.492 1.000 54.090  0 125 MET A CB  1 ? 
ATOM   1001 C CG  . MET A 1 125 ? 18.312 -31.655 28.403 1.000 47.866  0 125 MET A CG  1 ? 
ATOM   1002 S SD  . MET A 1 125 ? 18.287 -33.406 28.787 1.000 57.540  0 125 MET A SD  1 ? 
ATOM   1003 C CE  . MET A 1 125 ? 19.775 -33.460 29.799 1.000 57.993  0 125 MET A CE  1 ? 
ATOM   1004 N N   . SER A 1 126 ? 15.003 -29.356 30.585 1.000 53.155  0 126 SER A N   1 ? 
ATOM   1005 C CA  . SER A 1 126 ? 14.332 -28.377 31.416 1.000 48.647  0 126 SER A CA  1 ? 
ATOM   1006 C C   . SER A 1 126 ? 13.383 -29.071 32.407 1.000 57.192  0 126 SER A C   1 ? 
ATOM   1007 O O   . SER A 1 126 ? 13.364 -28.770 33.599 1.000 46.583  0 126 SER A O   1 ? 
ATOM   1008 C CB  . SER A 1 126 ? 13.597 -27.430 30.559 1.000 54.992  0 126 SER A CB  1 ? 
ATOM   1009 O OG  . SER A 1 126 ? 14.470 -26.571 29.845 1.000 53.467  0 126 SER A OG  1 ? 
ATOM   1010 N N   . TRP A 1 127 ? 12.605 -30.025 31.896 1.000 52.892  0 127 TRP A N   1 ? 
ATOM   1011 C CA  . TRP A 1 127 ? 11.738 -30.857 32.703 1.000 59.767  0 127 TRP A CA  1 ? 
ATOM   1012 C C   . TRP A 1 127 ? 12.518 -31.517 33.837 1.000 56.513  0 127 TRP A C   1 ? 
ATOM   1013 O O   . TRP A 1 127 ? 12.052 -31.564 34.977 1.000 54.941  0 127 TRP A O   1 ? 
ATOM   1014 C CB  . TRP A 1 127 ? 11.099 -31.902 31.781 1.000 61.440  0 127 TRP A CB  1 ? 
ATOM   1015 C CG  . TRP A 1 127 ? 10.277 -32.947 32.481 1.000 49.879  0 127 TRP A CG  1 ? 
ATOM   1016 C CD1 . TRP A 1 127 ? 8.944  -32.880 32.752 1.000 58.023  0 127 TRP A CD1 1 ? 
ATOM   1017 C CD2 . TRP A 1 127 ? 10.720 -34.231 32.944 1.000 50.984  0 127 TRP A CD2 1 ? 
ATOM   1018 N NE1 . TRP A 1 127 ? 8.525  -34.035 33.347 1.000 53.539  0 127 TRP A NE1 1 ? 
ATOM   1019 C CE2 . TRP A 1 127 ? 9.590  -34.878 33.487 1.000 57.435  0 127 TRP A CE2 1 ? 
ATOM   1020 C CE3 . TRP A 1 127 ? 11.947 -34.903 32.951 1.000 59.174  0 127 TRP A CE3 1 ? 
ATOM   1021 C CZ2 . TRP A 1 127 ? 9.658  -36.146 34.046 1.000 51.454  0 127 TRP A CZ2 1 ? 
ATOM   1022 C CZ3 . TRP A 1 127 ? 12.004 -36.174 33.483 1.000 55.880  0 127 TRP A CZ3 1 ? 
ATOM   1023 C CH2 . TRP A 1 127 ? 10.877 -36.784 34.017 1.000 55.010  0 127 TRP A CH2 1 ? 
ATOM   1024 N N   . GLY A 1 128 ? 13.719 -32.002 33.513 1.000 54.902  0 128 GLY A N   1 ? 
ATOM   1025 C CA  . GLY A 1 128 ? 14.520 -32.793 34.431 1.000 58.899  0 128 GLY A CA  1 ? 
ATOM   1026 C C   . GLY A 1 128 ? 15.253 -31.950 35.474 1.000 57.055  0 128 GLY A C   1 ? 
ATOM   1027 O O   . GLY A 1 128 ? 15.314 -32.374 36.623 1.000 52.318  0 128 GLY A O   1 ? 
ATOM   1028 N N   . VAL A 1 129 ? 15.829 -30.797 35.087 1.000 58.186  0 129 VAL A N   1 ? 
ATOM   1029 C CA  . VAL A 1 129 ? 16.507 -29.970 36.079 1.000 61.940  0 129 VAL A CA  1 ? 
ATOM   1030 C C   . VAL A 1 129 ? 15.502 -29.445 37.101 1.000 47.459  0 129 VAL A C   1 ? 
ATOM   1031 O O   . VAL A 1 129 ? 15.899 -29.054 38.183 1.000 58.668  0 129 VAL A O   1 ? 
ATOM   1032 C CB  . VAL A 1 129 ? 17.231 -28.682 35.660 1.000 54.285  0 129 VAL A CB  1 ? 
ATOM   1033 C CG1 . VAL A 1 129 ? 18.729 -28.798 35.598 1.000 57.966  0 129 VAL A CG1 1 ? 
ATOM   1034 C CG2 . VAL A 1 129 ? 16.553 -27.985 34.510 1.000 52.386  0 129 VAL A CG2 1 ? 
ATOM   1035 N N   . SER A 1 130 ? 14.274 -29.201 36.656 1.000 52.873  0 130 SER A N   1 ? 
ATOM   1036 C CA  . SER A 1 130 ? 13.289 -28.542 37.482 1.000 51.227  0 130 SER A CA  1 ? 
ATOM   1037 C C   . SER A 1 130 ? 12.858 -29.511 38.576 1.000 44.475  0 130 SER A C   1 ? 
ATOM   1038 O O   . SER A 1 130 ? 12.864 -30.727 38.392 1.000 56.247  0 130 SER A O   1 ? 
ATOM   1039 C CB  . SER A 1 130 ? 12.135 -28.059 36.669 1.000 52.333  0 130 SER A CB  1 ? 
ATOM   1040 O OG  . SER A 1 130 ? 11.332 -29.168 36.267 1.000 53.632  0 130 SER A OG  1 ? 
ATOM   1041 N N   . ASP A 1 131 ? 12.551 -28.947 39.735 1.000 56.841  0 131 ASP A N   1 ? 
ATOM   1042 C CA  . ASP A 1 131 ? 11.930 -29.689 40.821 1.000 54.814  0 131 ASP A CA  1 ? 
ATOM   1043 C C   . ASP A 1 131 ? 10.405 -29.617 40.746 1.000 48.661  0 131 ASP A C   1 ? 
ATOM   1044 O O   . ASP A 1 131 ? 9.713  -30.445 41.320 1.000 57.267  0 131 ASP A O   1 ? 
ATOM   1045 C CB  . ASP A 1 131 ? 12.440 -29.173 42.154 1.000 56.934  0 131 ASP A CB  1 ? 
ATOM   1046 C CG  . ASP A 1 131 ? 13.911 -29.450 42.380 1.000 54.462  0 131 ASP A CG  1 ? 
ATOM   1047 O OD1 . ASP A 1 131 ? 14.286 -30.630 42.255 1.000 55.016  0 131 ASP A OD1 1 ? 
ATOM   1048 O OD2 . ASP A 1 131 ? 14.658 -28.475 42.651 1.000 48.402  0 131 ASP A OD2 1 ? 
ATOM   1049 N N   . ASN A 1 132 ? 9.875  -28.611 40.048 1.000 50.907  0 132 ASN A N   1 ? 
ATOM   1050 C CA  . ASN A 1 132 ? 8.442  -28.390 40.000 1.000 52.268  0 132 ASN A CA  1 ? 
ATOM   1051 C C   . ASN A 1 132 ? 8.187  -27.379 38.889 1.000 53.027  0 132 ASN A C   1 ? 
ATOM   1052 O O   . ASN A 1 132 ? 9.080  -26.581 38.564 1.000 49.975  0 132 ASN A O   1 ? 
ATOM   1053 C CB  . ASN A 1 132 ? 7.971  -27.923 41.380 1.000 53.592  0 132 ASN A CB  1 ? 
ATOM   1054 C CG  . ASN A 1 132 ? 6.482  -27.695 41.537 1.000 52.928  0 132 ASN A CG  1 ? 
ATOM   1055 O OD1 . ASN A 1 132 ? 6.064  -26.971 42.454 1.000 62.873  0 132 ASN A OD1 1 ? 
ATOM   1056 N ND2 . ASN A 1 132 ? 5.678  -28.245 40.655 1.000 50.734  0 132 ASN A ND2 1 ? 
ATOM   1057 N N   . VAL A 1 133 ? 6.969  -27.403 38.329 1.000 47.862  0 133 VAL A N   1 ? 
ATOM   1058 C CA  . VAL A 1 133 ? 6.562  -26.408 37.351 1.000 52.716  0 133 VAL A CA  1 ? 
ATOM   1059 C C   . VAL A 1 133 ? 5.073  -26.073 37.484 1.000 52.566  0 133 VAL A C   1 ? 
ATOM   1060 O O   . VAL A 1 133 ? 4.203  -26.936 37.517 1.000 63.014  0 133 VAL A O   1 ? 
ATOM   1061 C CB  . VAL A 1 133 ? 7.015  -26.755 35.904 1.000 60.432  0 133 VAL A CB  1 ? 
ATOM   1062 C CG1 . VAL A 1 133 ? 7.507  -28.184 35.710 1.000 63.226  0 133 VAL A CG1 1 ? 
ATOM   1063 C CG2 . VAL A 1 133 ? 6.026  -26.344 34.829 1.000 59.807  0 133 VAL A CG2 1 ? 
ATOM   1064 N N   . ILE A 1 134 ? 4.804  -24.761 37.527 1.000 54.515  0 134 ILE A N   1 ? 
ATOM   1065 C CA  . ILE A 1 134 ? 3.511  -24.206 37.882 1.000 58.553  0 134 ILE A CA  1 ? 
ATOM   1066 C C   . ILE A 1 134 ? 3.092  -23.180 36.834 1.000 58.707  0 134 ILE A C   1 ? 
ATOM   1067 O O   . ILE A 1 134 ? 3.892  -22.777 35.995 1.000 51.326  0 134 ILE A O   1 ? 
ATOM   1068 C CB  . ILE A 1 134 ? 3.587  -23.550 39.273 1.000 59.856  0 134 ILE A CB  1 ? 
ATOM   1069 C CG1 . ILE A 1 134 ? 4.550  -22.347 39.281 1.000 54.900  0 134 ILE A CG1 1 ? 
ATOM   1070 C CG2 . ILE A 1 134 ? 3.943  -24.604 40.330 1.000 61.405  0 134 ILE A CG2 1 ? 
ATOM   1071 C CD1 . ILE A 1 134 ? 4.386  -21.444 40.478 1.000 54.729  0 134 ILE A CD1 1 ? 
ATOM   1072 N N   . LYS A 1 135 ? 1.841  -22.719 36.933 1.000 60.872  0 135 LYS A N   1 ? 
ATOM   1073 C CA  . LYS A 1 135 ? 1.306  -21.743 35.999 1.000 57.008  0 135 LYS A CA  1 ? 
ATOM   1074 C C   . LYS A 1 135 ? 1.507  -20.363 36.607 1.000 53.437  0 135 LYS A C   1 ? 
ATOM   1075 O O   . LYS A 1 135 ? 1.635  -20.248 37.815 1.000 59.664  0 135 LYS A O   1 ? 
ATOM   1076 C CB  . LYS A 1 135 ? -0.136 -22.051 35.568 1.000 58.305  0 135 LYS A CB  1 ? 
ATOM   1077 C CG  . LYS A 1 135 ? -1.112 -22.463 36.651 1.000 71.476  0 135 LYS A CG  1 ? 
ATOM   1078 C CD  . LYS A 1 135 ? -2.511 -22.851 36.187 1.000 73.732  0 135 LYS A CD  1 ? 
ATOM   1079 C CE  . LYS A 1 135 ? -2.584 -23.812 35.056 1.000 82.772  0 135 LYS A CE  1 ? 
ATOM   1080 N NZ  . LYS A 1 135 ? -3.983 -24.211 34.889 1.000 96.616  0 135 LYS A NZ  1 ? 
ATOM   1081 N N   . MET A 1 136 ? 1.587  -19.331 35.752 1.000 51.705  0 136 MET A N   1 ? 
ATOM   1082 C CA  . MET A 1 136 ? 1.786  -17.971 36.212 1.000 56.048  0 136 MET A CA  1 ? 
ATOM   1083 C C   . MET A 1 136 ? 0.801  -17.592 37.326 1.000 62.069  0 136 MET A C   1 ? 
ATOM   1084 O O   . MET A 1 136 ? 1.172  -16.899 38.274 1.000 61.460  0 136 MET A O   1 ? 
ATOM   1085 C CB  . MET A 1 136 ? 1.659  -17.013 35.031 1.000 56.594  0 136 MET A CB  1 ? 
ATOM   1086 C CG  . MET A 1 136 ? 1.985  -15.579 35.346 1.000 60.846  0 136 MET A CG  1 ? 
ATOM   1087 S SD  . MET A 1 136 ? 3.739  -15.391 35.721 1.000 60.621  0 136 MET A SD  1 ? 
ATOM   1088 C CE  . MET A 1 136 ? 4.364  -15.822 34.078 1.000 56.044  0 136 MET A CE  1 ? 
ATOM   1089 N N   . SER A 1 137 ? -0.444 -18.069 37.244 1.000 64.089  0 137 SER A N   1 ? 
ATOM   1090 C CA  . SER A 1 137 ? -1.479 -17.642 38.176 1.000 68.866  0 137 SER A CA  1 ? 
ATOM   1091 C C   . SER A 1 137 ? -1.328 -18.321 39.537 1.000 67.073  0 137 SER A C   1 ? 
ATOM   1092 O O   . SER A 1 137 ? -2.030 -17.935 40.476 1.000 62.101  0 137 SER A O   1 ? 
ATOM   1093 C CB  . SER A 1 137 ? -2.883 -17.843 37.609 1.000 62.820  0 137 SER A CB  1 ? 
ATOM   1094 O OG  . SER A 1 137 ? -3.201 -19.226 37.571 1.000 64.912  0 137 SER A OG  1 ? 
ATOM   1095 N N   . GLN A 1 138 ? -0.414 -19.297 39.658 1.000 61.251  0 138 GLN A N   1 ? 
ATOM   1096 C CA  . GLN A 1 138 ? -0.126 -19.925 40.941 1.000 57.248  0 138 GLN A CA  1 ? 
ATOM   1097 C C   . GLN A 1 138 ? 1.003  -19.223 41.707 1.000 57.991  0 138 GLN A C   1 ? 
ATOM   1098 O O   . GLN A 1 138 ? 1.246  -19.541 42.865 1.000 67.753  0 138 GLN A O   1 ? 
ATOM   1099 C CB  . GLN A 1 138 ? 0.249  -21.391 40.764 1.000 60.197  0 138 GLN A CB  1 ? 
ATOM   1100 C CG  . GLN A 1 138 ? -0.914 -22.300 40.390 1.000 59.681  0 138 GLN A CG  1 ? 
ATOM   1101 C CD  . GLN A 1 138 ? -0.449 -23.703 40.064 1.000 56.702  0 138 GLN A CD  1 ? 
ATOM   1102 O OE1 . GLN A 1 138 ? 0.279  -23.915 39.098 1.000 55.311  0 138 GLN A OE1 1 ? 
ATOM   1103 N NE2 . GLN A 1 138 ? -0.834 -24.693 40.848 1.000 59.893  0 138 GLN A NE2 1 ? 
ATOM   1104 N N   . LEU A 1 139 ? 1.687  -18.269 41.085 1.000 63.369  0 139 LEU A N   1 ? 
ATOM   1105 C CA  . LEU A 1 139 ? 2.964  -17.817 41.608 1.000 62.426  0 139 LEU A CA  1 ? 
ATOM   1106 C C   . LEU A 1 139 ? 2.762  -16.895 42.814 1.000 63.037  0 139 LEU A C   1 ? 
ATOM   1107 O O   . LEU A 1 139 ? 3.532  -16.983 43.782 1.000 54.829  0 139 LEU A O   1 ? 
ATOM   1108 C CB  . LEU A 1 139 ? 3.796  -17.140 40.523 1.000 59.151  0 139 LEU A CB  1 ? 
ATOM   1109 C CG  . LEU A 1 139 ? 5.175  -16.610 40.950 1.000 55.313  0 139 LEU A CG  1 ? 
ATOM   1110 C CD1 . LEU A 1 139 ? 5.993  -17.697 41.607 1.000 56.902  0 139 LEU A CD1 1 ? 
ATOM   1111 C CD2 . LEU A 1 139 ? 5.904  -16.064 39.748 1.000 57.148  0 139 LEU A CD2 1 ? 
ATOM   1112 N N   . LYS A 1 140 ? 1.743  -16.023 42.756 1.000 60.140  0 140 LYS A N   1 ? 
ATOM   1113 C CA  . LYS A 1 140 ? 1.416  -15.124 43.868 1.000 64.062  0 140 LYS A CA  1 ? 
ATOM   1114 C C   . LYS A 1 140 ? 1.133  -15.898 45.158 1.000 53.429  0 140 LYS A C   1 ? 
ATOM   1115 O O   . LYS A 1 140 ? 1.350  -15.361 46.231 1.000 54.894  0 140 LYS A O   1 ? 
ATOM   1116 C CB  . LYS A 1 140 ? 0.251  -14.169 43.554 1.000 74.052  0 140 LYS A CB  1 ? 
ATOM   1117 C CG  . LYS A 1 140 ? -1.164 -14.735 43.618 1.000 72.526  0 140 LYS A CG  1 ? 
ATOM   1118 C CD  . LYS A 1 140 ? -2.250 -13.963 42.867 1.000 77.769  0 140 LYS A CD  1 ? 
ATOM   1119 C CE  . LYS A 1 140 ? -2.378 -12.502 43.209 1.000 102.435 0 140 LYS A CE  1 ? 
ATOM   1120 N NZ  . LYS A 1 140 ? -2.835 -12.188 44.570 1.000 105.066 0 140 LYS A NZ  1 ? 
ATOM   1121 N N   . ASP A 1 141 ? 0.747  -17.181 45.074 1.000 51.990  0 141 ASP A N   1 ? 
ATOM   1122 C CA  . ASP A 1 141 ? 0.281  -17.906 46.253 1.000 62.029  0 141 ASP A CA  1 ? 
ATOM   1123 C C   . ASP A 1 141 ? 1.180  -19.081 46.603 1.000 66.651  0 141 ASP A C   1 ? 
ATOM   1124 O O   . ASP A 1 141 ? 0.920  -19.783 47.580 1.000 60.833  0 141 ASP A O   1 ? 
ATOM   1125 C CB  . ASP A 1 141 ? -1.142 -18.418 46.033 1.000 67.894  0 141 ASP A CB  1 ? 
ATOM   1126 C CG  . ASP A 1 141 ? -2.200 -17.335 45.824 1.000 62.659  0 141 ASP A CG  1 ? 
ATOM   1127 O OD1 . ASP A 1 141 ? -2.114 -16.280 46.486 1.000 72.057  0 141 ASP A OD1 1 ? 
ATOM   1128 O OD2 . ASP A 1 141 ? -3.101 -17.556 45.015 1.000 68.187  0 141 ASP A OD2 1 ? 
ATOM   1129 N N   . PHE A 1 142 ? 2.209  -19.312 45.778 1.000 60.690  0 142 PHE A N   1 ? 
ATOM   1130 C CA  . PHE A 1 142 ? 3.108  -20.428 46.018 1.000 60.754  0 142 PHE A CA  1 ? 
ATOM   1131 C C   . PHE A 1 142 ? 3.762  -20.270 47.396 1.000 53.977  0 142 PHE A C   1 ? 
ATOM   1132 O O   . PHE A 1 142 ? 4.255  -19.199 47.720 1.000 50.000  0 142 PHE A O   1 ? 
ATOM   1133 C CB  . PHE A 1 142 ? 4.135  -20.473 44.884 1.000 54.708  0 142 PHE A CB  1 ? 
ATOM   1134 C CG  . PHE A 1 142 ? 4.969  -21.731 44.916 1.000 51.783  0 142 PHE A CG  1 ? 
ATOM   1135 C CD1 . PHE A 1 142 ? 6.136  -21.779 45.653 1.000 50.179  0 142 PHE A CD1 1 ? 
ATOM   1136 C CD2 . PHE A 1 142 ? 4.557  -22.873 44.239 1.000 52.222  0 142 PHE A CD2 1 ? 
ATOM   1137 C CE1 . PHE A 1 142 ? 6.885  -22.936 45.676 1.000 50.715  0 142 PHE A CE1 1 ? 
ATOM   1138 C CE2 . PHE A 1 142 ? 5.312  -24.017 44.269 1.000 51.473  0 142 PHE A CE2 1 ? 
ATOM   1139 C CZ  . PHE A 1 142 ? 6.473  -24.054 44.987 1.000 56.823  0 142 PHE A CZ  1 ? 
ATOM   1140 N N   . ASN A 1 143 ? 3.760  -21.333 48.203 1.000 51.546  0 143 ASN A N   1 ? 
ATOM   1141 C CA  . ASN A 1 143 ? 4.416  -21.304 49.498 1.000 53.399  0 143 ASN A CA  1 ? 
ATOM   1142 C C   . ASN A 1 143 ? 5.881  -21.720 49.355 1.000 49.852  0 143 ASN A C   1 ? 
ATOM   1143 O O   . ASN A 1 143 ? 6.189  -22.896 49.372 1.000 51.054  0 143 ASN A O   1 ? 
ATOM   1144 C CB  . ASN A 1 143 ? 3.726  -22.196 50.519 1.000 55.947  0 143 ASN A CB  1 ? 
ATOM   1145 C CG  . ASN A 1 143 ? 4.352  -22.073 51.892 1.000 59.778  0 143 ASN A CG  1 ? 
ATOM   1146 O OD1 . ASN A 1 143 ? 5.287  -21.297 52.085 1.000 50.303  0 143 ASN A OD1 1 ? 
ATOM   1147 N ND2 . ASN A 1 143 ? 3.886  -22.845 52.858 1.000 63.606  0 143 ASN A ND2 1 ? 
ATOM   1148 N N   . PHE A 1 144 ? 6.774  -20.731 49.279 1.000 54.411  0 144 PHE A N   1 ? 
ATOM   1149 C CA  . PHE A 1 144 ? 8.197  -20.969 49.107 1.000 53.925  0 144 PHE A CA  1 ? 
ATOM   1150 C C   . PHE A 1 144 ? 8.864  -21.479 50.383 1.000 59.959  0 144 PHE A C   1 ? 
ATOM   1151 O O   . PHE A 1 144 ? 10.038 -21.845 50.335 1.000 53.258  0 144 PHE A O   1 ? 
ATOM   1152 C CB  . PHE A 1 144 ? 8.885  -19.689 48.621 1.000 49.582  0 144 PHE A CB  1 ? 
ATOM   1153 C CG  . PHE A 1 144 ? 8.560  -19.364 47.177 1.000 51.502  0 144 PHE A CG  1 ? 
ATOM   1154 C CD1 . PHE A 1 144 ? 9.233  -20.012 46.142 1.000 56.761  0 144 PHE A CD1 1 ? 
ATOM   1155 C CD2 . PHE A 1 144 ? 7.591  -18.422 46.850 1.000 51.688  0 144 PHE A CD2 1 ? 
ATOM   1156 C CE1 . PHE A 1 144 ? 8.959  -19.716 44.812 1.000 54.121  0 144 PHE A CE1 1 ? 
ATOM   1157 C CE2 . PHE A 1 144 ? 7.318  -18.129 45.519 1.000 54.752  0 144 PHE A CE2 1 ? 
ATOM   1158 C CZ  . PHE A 1 144 ? 7.993  -18.792 44.503 1.000 60.540  0 144 PHE A CZ  1 ? 
ATOM   1159 N N   . ASN A 1 145 ? 8.136  -21.549 51.506 1.000 61.437  0 145 ASN A N   1 ? 
ATOM   1160 C CA  . ASN A 1 145 ? 8.720  -22.082 52.729 1.000 53.481  0 145 ASN A CA  1 ? 
ATOM   1161 C C   . ASN A 1 145 ? 8.649  -23.600 52.761 1.000 52.847  0 145 ASN A C   1 ? 
ATOM   1162 O O   . ASN A 1 145 ? 9.392  -24.222 53.546 1.000 50.074  0 145 ASN A O   1 ? 
ATOM   1163 C CB  . ASN A 1 145 ? 8.072  -21.498 53.988 1.000 57.739  0 145 ASN A CB  1 ? 
ATOM   1164 C CG  . ASN A 1 145 ? 8.416  -20.043 54.162 1.000 52.276  0 145 ASN A CG  1 ? 
ATOM   1165 O OD1 . ASN A 1 145 ? 9.603  -19.685 54.180 1.000 55.655  0 145 ASN A OD1 1 ? 
ATOM   1166 N ND2 . ASN A 1 145 ? 7.407  -19.193 54.283 1.000 58.736  0 145 ASN A ND2 1 ? 
ATOM   1167 N N   . LYS A 1 146 ? 7.756  -24.183 51.938 1.000 55.312  0 146 LYS A N   1 ? 
ATOM   1168 C CA  . LYS A 1 146 ? 7.587  -25.634 51.890 1.000 63.508  0 146 LYS A CA  1 ? 
ATOM   1169 C C   . LYS A 1 146 ? 7.612  -26.107 50.430 1.000 67.254  0 146 LYS A C   1 ? 
ATOM   1170 O O   . LYS A 1 146 ? 6.661  -26.687 49.906 1.000 60.273  0 146 LYS A O   1 ? 
ATOM   1171 C CB  . LYS A 1 146 ? 6.313  -26.062 52.621 1.000 71.277  0 146 LYS A CB  1 ? 
ATOM   1172 C CG  . LYS A 1 146 ? 6.056  -25.350 53.952 1.000 85.591  0 146 LYS A CG  1 ? 
ATOM   1173 C CD  . LYS A 1 146 ? 4.979  -25.954 54.853 1.000 90.340  0 146 LYS A CD  1 ? 
ATOM   1174 C CE  . LYS A 1 146 ? 5.473  -27.231 55.478 1.000 91.024  0 146 LYS A CE  1 ? 
ATOM   1175 N NZ  . LYS A 1 146 ? 4.372  -28.096 55.903 1.000 93.972  0 146 LYS A NZ  1 ? 
ATOM   1176 N N   . PRO A 1 147 ? 8.725  -25.880 49.706 1.000 60.046  0 147 PRO A N   1 ? 
ATOM   1177 C CA  . PRO A 1 147 ? 8.782  -26.221 48.289 1.000 55.891  0 147 PRO A CA  1 ? 
ATOM   1178 C C   . PRO A 1 147 ? 8.963  -27.727 48.147 1.000 49.403  0 147 PRO A C   1 ? 
ATOM   1179 O O   . PRO A 1 147 ? 9.789  -28.327 48.831 1.000 47.980  0 147 PRO A O   1 ? 
ATOM   1180 C CB  . PRO A 1 147 ? 9.986  -25.404 47.824 1.000 52.064  0 147 PRO A CB  1 ? 
ATOM   1181 C CG  . PRO A 1 147 ? 10.893 -25.422 49.024 1.000 55.902  0 147 PRO A CG  1 ? 
ATOM   1182 C CD  . PRO A 1 147 ? 9.980  -25.309 50.216 1.000 57.325  0 147 PRO A CD  1 ? 
ATOM   1183 N N   . ARG A 1 148 ? 8.160  -28.340 47.284 1.000 53.537  0 148 ARG A N   1 ? 
ATOM   1184 C CA  . ARG A 1 148 ? 8.165  -29.788 47.110 1.000 59.489  0 148 ARG A CA  1 ? 
ATOM   1185 C C   . ARG A 1 148 ? 8.402  -30.146 45.641 1.000 54.634  0 148 ARG A C   1 ? 
ATOM   1186 O O   . ARG A 1 148 ? 8.188  -29.321 44.748 1.000 49.652  0 148 ARG A O   1 ? 
ATOM   1187 C CB  . ARG A 1 148 ? 6.824  -30.382 47.554 1.000 61.572  0 148 ARG A CB  1 ? 
ATOM   1188 C CG  . ARG A 1 148 ? 6.401  -30.063 48.988 1.000 70.597  0 148 ARG A CG  1 ? 
ATOM   1189 C CD  . ARG A 1 148 ? 7.293  -30.669 50.048 1.000 78.635  0 148 ARG A CD  1 ? 
ATOM   1190 N NE  . ARG A 1 148 ? 7.068  -30.147 51.407 1.000 95.027  0 148 ARG A NE  1 ? 
ATOM   1191 C CZ  . ARG A 1 148 ? 7.951  -29.458 52.147 1.000 86.694  0 148 ARG A CZ  1 ? 
ATOM   1192 N NH1 . ARG A 1 148 ? 7.763  -29.296 53.441 1.000 88.095  0 148 ARG A NH1 1 ? 
ATOM   1193 N NH2 . ARG A 1 148 ? 9.057  -28.967 51.612 1.000 88.656  0 148 ARG A NH2 1 ? 
ATOM   1194 N N   . PHE A 1 149 ? 8.829  -31.398 45.413 1.000 57.254  0 149 PHE A N   1 ? 
ATOM   1195 C CA  . PHE A 1 149 ? 8.997  -31.965 44.087 1.000 54.848  0 149 PHE A CA  1 ? 
ATOM   1196 C C   . PHE A 1 149 ? 7.646  -32.383 43.504 1.000 65.551  0 149 PHE A C   1 ? 
ATOM   1197 O O   . PHE A 1 149 ? 6.893  -33.087 44.166 1.000 61.851  0 149 PHE A O   1 ? 
ATOM   1198 C CB  . PHE A 1 149 ? 9.865  -33.217 44.080 1.000 55.476  0 149 PHE A CB  1 ? 
ATOM   1199 C CG  . PHE A 1 149 ? 9.988  -33.792 42.673 1.000 59.503  0 149 PHE A CG  1 ? 
ATOM   1200 C CD1 . PHE A 1 149 ? 9.050  -34.692 42.181 1.000 60.059  0 149 PHE A CD1 1 ? 
ATOM   1201 C CD2 . PHE A 1 149 ? 10.991 -33.350 41.814 1.000 56.900  0 149 PHE A CD2 1 ? 
ATOM   1202 C CE1 . PHE A 1 149 ? 9.141  -35.162 40.876 1.000 63.971  0 149 PHE A CE1 1 ? 
ATOM   1203 C CE2 . PHE A 1 149 ? 11.065 -33.803 40.505 1.000 54.425  0 149 PHE A CE2 1 ? 
ATOM   1204 C CZ  . PHE A 1 149 ? 10.142 -34.714 40.042 1.000 62.445  0 149 PHE A CZ  1 ? 
ATOM   1205 N N   . ASP A 1 150 ? 7.366  -31.972 42.262 1.000 60.685  0 150 ASP A N   1 ? 
ATOM   1206 C CA  . ASP A 1 150 ? 6.171  -32.415 41.554 1.000 59.889  0 150 ASP A CA  1 ? 
ATOM   1207 C C   . ASP A 1 150 ? 6.453  -32.415 40.052 1.000 59.863  0 150 ASP A C   1 ? 
ATOM   1208 O O   . ASP A 1 150 ? 7.300  -31.653 39.592 1.000 54.333  0 150 ASP A O   1 ? 
ATOM   1209 C CB  . ASP A 1 150 ? 4.978  -31.534 41.875 1.000 61.633  0 150 ASP A CB  1 ? 
ATOM   1210 C CG  . ASP A 1 150 ? 3.595  -32.149 41.651 1.000 64.363  0 150 ASP A CG  1 ? 
ATOM   1211 O OD1 . ASP A 1 150 ? 3.503  -33.338 41.288 1.000 56.679  0 150 ASP A OD1 1 ? 
ATOM   1212 O OD2 . ASP A 1 150 ? 2.601  -31.424 41.812 1.000 68.545  0 150 ASP A OD2 1 ? 
ATOM   1213 N N   . PHE A 1 151 ? 5.716  -33.241 39.306 1.000 58.687  0 151 PHE A N   1 ? 
ATOM   1214 C CA  . PHE A 1 151 ? 5.895  -33.348 37.861 1.000 59.218  0 151 PHE A CA  1 ? 
ATOM   1215 C C   . PHE A 1 151 ? 5.040  -32.339 37.107 1.000 57.747  0 151 PHE A C   1 ? 
ATOM   1216 O O   . PHE A 1 151 ? 3.902  -32.117 37.492 1.000 58.220  0 151 PHE A O   1 ? 
ATOM   1217 C CB  . PHE A 1 151 ? 5.408  -34.702 37.343 1.000 51.481  0 151 PHE A CB  1 ? 
ATOM   1218 C CG  . PHE A 1 151 ? 6.283  -35.877 37.755 1.000 50.887  0 151 PHE A CG  1 ? 
ATOM   1219 C CD1 . PHE A 1 151 ? 7.539  -36.069 37.196 1.000 55.964  0 151 PHE A CD1 1 ? 
ATOM   1220 C CD2 . PHE A 1 151 ? 5.826  -36.820 38.645 1.000 48.595  0 151 PHE A CD2 1 ? 
ATOM   1221 C CE1 . PHE A 1 151 ? 8.298  -37.170 37.542 1.000 53.683  0 151 PHE A CE1 1 ? 
ATOM   1222 C CE2 . PHE A 1 151 ? 6.606  -37.897 39.000 1.000 54.345  0 151 PHE A CE2 1 ? 
ATOM   1223 C CZ  . PHE A 1 151 ? 7.831  -38.077 38.444 1.000 44.588  0 151 PHE A CZ  1 ? 
ATOM   1224 N N   . TYR A 1 152 ? 5.598  -31.755 36.033 1.000 61.269  0 152 TYR A N   1 ? 
ATOM   1225 C CA  . TYR A 1 152 ? 4.820  -30.972 35.079 1.000 62.638  0 152 TYR A CA  1 ? 
ATOM   1226 C C   . TYR A 1 152 ? 3.635  -31.793 34.571 1.000 64.231  0 152 TYR A C   1 ? 
ATOM   1227 O O   . TYR A 1 152 ? 3.799  -32.967 34.211 1.000 56.452  0 152 TYR A O   1 ? 
ATOM   1228 C CB  . TYR A 1 152 ? 5.716  -30.641 33.888 1.000 58.745  0 152 TYR A CB  1 ? 
ATOM   1229 C CG  . TYR A 1 152 ? 5.186  -29.725 32.789 1.000 57.662  0 152 TYR A CG  1 ? 
ATOM   1230 C CD1 . TYR A 1 152 ? 4.399  -28.609 33.053 1.000 52.631  0 152 TYR A CD1 1 ? 
ATOM   1231 C CD2 . TYR A 1 152 ? 5.546  -29.967 31.468 1.000 55.652  0 152 TYR A CD2 1 ? 
ATOM   1232 C CE1 . TYR A 1 152 ? 3.980  -27.770 32.034 1.000 59.642  0 152 TYR A CE1 1 ? 
ATOM   1233 C CE2 . TYR A 1 152 ? 5.137  -29.138 30.444 1.000 56.859  0 152 TYR A CE2 1 ? 
ATOM   1234 C CZ  . TYR A 1 152 ? 4.338  -28.051 30.725 1.000 55.059  0 152 TYR A CZ  1 ? 
ATOM   1235 O OH  . TYR A 1 152 ? 3.963  -27.256 29.688 1.000 54.495  0 152 TYR A OH  1 ? 
ATOM   1236 N N   . GLU A 1 153 ? 2.460  -31.153 34.545 1.000 59.360  0 153 GLU A N   1 ? 
ATOM   1237 C CA  . GLU A 1 153 ? 1.260  -31.704 33.925 1.000 62.579  0 153 GLU A CA  1 ? 
ATOM   1238 C C   . GLU A 1 153 ? 1.246  -31.241 32.468 1.000 60.424  0 153 GLU A C   1 ? 
ATOM   1239 O O   . GLU A 1 153 ? 0.623  -30.246 32.123 1.000 63.089  0 153 GLU A O   1 ? 
ATOM   1240 C CB  . GLU A 1 153 ? 0.096  -31.178 34.775 1.000 70.823  0 153 GLU A CB  1 ? 
ATOM   1241 C CG  . GLU A 1 153 ? -1.244 -31.881 34.565 1.000 72.127  0 153 GLU A CG  1 ? 
ATOM   1242 C CD  . GLU A 1 153 ? -1.233 -33.349 34.964 1.000 75.391  0 153 GLU A CD  1 ? 
ATOM   1243 O OE1 . GLU A 1 153 ? -0.381 -33.736 35.788 1.000 70.276  0 153 GLU A OE1 1 ? 
ATOM   1244 O OE2 . GLU A 1 153 ? -2.044 -34.116 34.409 1.000 68.042  0 153 GLU A OE2 1 ? 
ATOM   1245 N N   . GLY A 1 154 ? 2.033  -31.923 31.632 1.000 65.492  0 154 GLY A N   1 ? 
ATOM   1246 C CA  . GLY A 1 154 ? 2.333  -31.476 30.285 1.000 57.663  0 154 GLY A CA  1 ? 
ATOM   1247 C C   . GLY A 1 154 ? 3.421  -32.339 29.658 1.000 61.974  0 154 GLY A C   1 ? 
ATOM   1248 O O   . GLY A 1 154 ? 3.993  -33.233 30.305 1.000 59.013  0 154 GLY A O   1 ? 
ATOM   1249 N N   . ALA A 1 155 ? 3.715  -32.042 28.391 1.000 65.145  0 155 ALA A N   1 ? 
ATOM   1250 C CA  . ALA A 1 155 ? 4.590  -32.900 27.609 1.000 65.677  0 155 ALA A CA  1 ? 
ATOM   1251 C C   . ALA A 1 155 ? 6.034  -32.390 27.647 1.000 59.347  0 155 ALA A C   1 ? 
ATOM   1252 O O   . ALA A 1 155 ? 6.323  -31.212 27.896 1.000 55.669  0 155 ALA A O   1 ? 
ATOM   1253 C CB  . ALA A 1 155 ? 4.086  -32.958 26.183 1.000 76.212  0 155 ALA A CB  1 ? 
ATOM   1254 N N   . VAL A 1 156 ? 6.935  -33.295 27.288 1.000 50.963  0 156 VAL A N   1 ? 
ATOM   1255 C CA  . VAL A 1 156 ? 8.288  -32.942 26.915 1.000 60.846  0 156 VAL A CA  1 ? 
ATOM   1256 C C   . VAL A 1 156 ? 8.537  -33.288 25.449 1.000 62.371  0 156 VAL A C   1 ? 
ATOM   1257 O O   . VAL A 1 156 ? 7.829  -34.097 24.862 1.000 65.444  0 156 VAL A O   1 ? 
ATOM   1258 C CB  . VAL A 1 156 ? 9.248  -33.712 27.826 1.000 66.062  0 156 VAL A CB  1 ? 
ATOM   1259 C CG1 . VAL A 1 156 ? 8.922  -33.491 29.303 1.000 73.755  0 156 VAL A CG1 1 ? 
ATOM   1260 C CG2 . VAL A 1 156 ? 9.252  -35.184 27.451 1.000 70.466  0 156 VAL A CG2 1 ? 
ATOM   1261 N N   . TYR A 1 157 ? 9.581  -32.691 24.874 1.000 67.010  0 157 TYR A N   1 ? 
ATOM   1262 C CA  . TYR A 1 157 ? 10.199 -33.214 23.663 1.000 69.446  0 157 TYR A CA  1 ? 
ATOM   1263 C C   . TYR A 1 157 ? 11.698 -33.496 23.950 1.000 72.421  0 157 TYR A C   1 ? 
ATOM   1264 O O   . TYR A 1 157 ? 12.202 -34.419 23.275 1.000 74.773  0 157 TYR A O   1 ? 
ATOM   1265 C CB  . TYR A 1 157 ? 9.953  -32.202 22.548 1.000 57.576  0 157 TYR A CB  1 ? 
ATOM   1266 C CG  . TYR A 1 157 ? 10.766 -30.930 22.718 1.000 56.821  0 157 TYR A CG  1 ? 
ATOM   1267 C CD1 . TYR A 1 157 ? 12.080 -30.842 22.266 1.000 56.911  0 157 TYR A CD1 1 ? 
ATOM   1268 C CD2 . TYR A 1 157 ? 10.203 -29.808 23.315 1.000 61.974  0 157 TYR A CD2 1 ? 
ATOM   1269 C CE1 . TYR A 1 157 ? 12.810 -29.669 22.421 1.000 55.480  0 157 TYR A CE1 1 ? 
ATOM   1270 C CE2 . TYR A 1 157 ? 10.911 -28.633 23.452 1.000 56.569  0 157 TYR A CE2 1 ? 
ATOM   1271 C CZ  . TYR A 1 157 ? 12.222 -28.568 23.015 1.000 59.051  0 157 TYR A CZ  1 ? 
ATOM   1272 O OH  . TYR A 1 157 ? 12.906 -27.400 23.219 1.000 56.926  0 157 TYR A OH  1 ? 
ATOM   1273 O OXT . TYR A 1 157 ? 12.318 -32.825 24.820 1.000 75.628  0 157 TYR A OXT 1 ? 
ATOM   1274 N N   . MET B 1 1   ? 49.536 -41.083 21.470 1.000 106.788 0 1   MET B N   1 ? 
ATOM   1275 C CA  . MET B 1 1   ? 48.485 -40.130 21.921 1.000 102.632 0 1   MET B CA  1 ? 
ATOM   1276 C C   . MET B 1 1   ? 47.591 -40.840 22.946 1.000 96.954  0 1   MET B C   1 ? 
ATOM   1277 O O   . MET B 1 1   ? 46.951 -41.846 22.645 1.000 93.398  0 1   MET B O   1 ? 
ATOM   1278 C CB  . MET B 1 1   ? 47.655 -39.586 20.742 1.000 91.333  0 1   MET B CB  1 ? 
ATOM   1279 N N   . PRO B 1 2   ? 47.517 -40.363 24.210 1.000 91.930  0 2   PRO B N   1 ? 
ATOM   1280 C CA  . PRO B 1 2   ? 46.352 -40.639 25.062 1.000 85.077  0 2   PRO B CA  1 ? 
ATOM   1281 C C   . PRO B 1 2   ? 45.084 -40.100 24.395 1.000 77.140  0 2   PRO B C   1 ? 
ATOM   1282 O O   . PRO B 1 2   ? 45.149 -39.172 23.590 1.000 76.486  0 2   PRO B O   1 ? 
ATOM   1283 C CB  . PRO B 1 2   ? 46.643 -39.916 26.398 1.000 88.353  0 2   PRO B CB  1 ? 
ATOM   1284 C CG  . PRO B 1 2   ? 48.116 -39.508 26.333 1.000 91.983  0 2   PRO B CG  1 ? 
ATOM   1285 C CD  . PRO B 1 2   ? 48.547 -39.545 24.873 1.000 91.378  0 2   PRO B CD  1 ? 
ATOM   1286 N N   . LYS B 1 3   ? 43.929 -40.687 24.728 1.000 71.894  0 3   LYS B N   1 ? 
ATOM   1287 C CA  . LYS B 1 3   ? 42.654 -40.295 24.136 1.000 76.261  0 3   LYS B CA  1 ? 
ATOM   1288 C C   . LYS B 1 3   ? 41.644 -39.940 25.232 1.000 68.638  0 3   LYS B C   1 ? 
ATOM   1289 O O   . LYS B 1 3   ? 41.655 -40.546 26.295 1.000 62.858  0 3   LYS B O   1 ? 
ATOM   1290 C CB  . LYS B 1 3   ? 42.171 -41.465 23.273 1.000 82.091  0 3   LYS B CB  1 ? 
ATOM   1291 C CG  . LYS B 1 3   ? 42.910 -41.637 21.945 1.000 86.873  0 3   LYS B CG  1 ? 
ATOM   1292 C CD  . LYS B 1 3   ? 42.751 -42.981 21.244 1.000 88.462  0 3   LYS B CD  1 ? 
ATOM   1293 C CE  . LYS B 1 3   ? 43.672 -43.023 20.068 1.000 87.850  0 3   LYS B CE  1 ? 
ATOM   1294 N NZ  . LYS B 1 3   ? 43.542 -44.275 19.335 1.000 91.411  0 3   LYS B NZ  1 ? 
ATOM   1295 N N   . LYS B 1 4   ? 40.760 -38.973 24.969 1.000 72.537  0 4   LYS B N   1 ? 
ATOM   1296 C CA  . LYS B 1 4   ? 39.750 -38.573 25.944 1.000 70.187  0 4   LYS B CA  1 ? 
ATOM   1297 C C   . LYS B 1 4   ? 38.377 -38.858 25.352 1.000 67.792  0 4   LYS B C   1 ? 
ATOM   1298 O O   . LYS B 1 4   ? 38.214 -38.779 24.134 1.000 60.508  0 4   LYS B O   1 ? 
ATOM   1299 C CB  . LYS B 1 4   ? 39.840 -37.076 26.285 1.000 70.554  0 4   LYS B CB  1 ? 
ATOM   1300 C CG  . LYS B 1 4   ? 41.177 -36.518 26.794 1.000 74.466  0 4   LYS B CG  1 ? 
ATOM   1301 C CD  . LYS B 1 4   ? 41.761 -36.998 28.130 1.000 70.781  0 4   LYS B CD  1 ? 
ATOM   1302 C CE  . LYS B 1 4   ? 41.798 -35.955 29.223 1.000 89.430  0 4   LYS B CE  1 ? 
ATOM   1303 N NZ  . LYS B 1 4   ? 42.489 -34.678 28.945 1.000 84.647  0 4   LYS B NZ  1 ? 
ATOM   1304 N N   . THR B 1 5   ? 37.382 -39.147 26.206 1.000 65.390  0 5   THR B N   1 ? 
ATOM   1305 C CA  . THR B 1 5   ? 36.015 -39.322 25.735 1.000 60.443  0 5   THR B CA  1 ? 
ATOM   1306 C C   . THR B 1 5   ? 35.264 -38.009 25.898 1.000 67.375  0 5   THR B C   1 ? 
ATOM   1307 O O   . THR B 1 5   ? 35.677 -37.164 26.693 1.000 58.411  0 5   THR B O   1 ? 
ATOM   1308 C CB  . THR B 1 5   ? 35.326 -40.445 26.504 1.000 66.587  0 5   THR B CB  1 ? 
ATOM   1309 O OG1 . THR B 1 5   ? 35.318 -40.080 27.884 1.000 64.781  0 5   THR B OG1 1 ? 
ATOM   1310 C CG2 . THR B 1 5   ? 36.029 -41.776 26.299 1.000 68.166  0 5   THR B CG2 1 ? 
ATOM   1311 N N   . ILE B 1 6   ? 34.157 -37.873 25.154 1.000 64.589  0 6   ILE B N   1 ? 
ATOM   1312 C CA  . ILE B 1 6   ? 33.334 -36.673 25.184 1.000 62.569  0 6   ILE B CA  1 ? 
ATOM   1313 C C   . ILE B 1 6   ? 31.845 -37.029 25.311 1.000 61.859  0 6   ILE B C   1 ? 
ATOM   1314 O O   . ILE B 1 6   ? 31.418 -38.160 25.082 1.000 54.679  0 6   ILE B O   1 ? 
ATOM   1315 C CB  . ILE B 1 6   ? 33.562 -35.768 23.957 1.000 66.035  0 6   ILE B CB  1 ? 
ATOM   1316 C CG1 . ILE B 1 6   ? 33.281 -36.486 22.648 1.000 71.028  0 6   ILE B CG1 1 ? 
ATOM   1317 C CG2 . ILE B 1 6   ? 34.955 -35.163 23.960 1.000 74.004  0 6   ILE B CG2 1 ? 
ATOM   1318 C CD1 . ILE B 1 6   ? 31.870 -36.319 22.130 1.000 67.589  0 6   ILE B CD1 1 ? 
ATOM   1319 N N   . TYR B 1 7   ? 31.058 -36.021 25.718 1.000 56.783  0 7   TYR B N   1 ? 
ATOM   1320 C CA  . TYR B 1 7   ? 29.619 -36.020 25.525 1.000 58.784  0 7   TYR B CA  1 ? 
ATOM   1321 C C   . TYR B 1 7   ? 29.295 -35.103 24.348 1.000 52.615  0 7   TYR B C   1 ? 
ATOM   1322 O O   . TYR B 1 7   ? 29.708 -33.942 24.345 1.000 56.394  0 7   TYR B O   1 ? 
ATOM   1323 C CB  . TYR B 1 7   ? 28.905 -35.529 26.791 1.000 64.496  0 7   TYR B CB  1 ? 
ATOM   1324 C CG  . TYR B 1 7   ? 27.397 -35.332 26.698 1.000 55.620  0 7   TYR B CG  1 ? 
ATOM   1325 C CD1 . TYR B 1 7   ? 26.862 -34.132 26.243 1.000 50.867  0 7   TYR B CD1 1 ? 
ATOM   1326 C CD2 . TYR B 1 7   ? 26.516 -36.322 27.132 1.000 59.986  0 7   TYR B CD2 1 ? 
ATOM   1327 C CE1 . TYR B 1 7   ? 25.489 -33.938 26.196 1.000 60.092  0 7   TYR B CE1 1 ? 
ATOM   1328 C CE2 . TYR B 1 7   ? 25.138 -36.131 27.102 1.000 52.866  0 7   TYR B CE2 1 ? 
ATOM   1329 C CZ  . TYR B 1 7   ? 24.624 -34.932 26.637 1.000 55.666  0 7   TYR B CZ  1 ? 
ATOM   1330 O OH  . TYR B 1 7   ? 23.266 -34.752 26.560 1.000 63.387  0 7   TYR B OH  1 ? 
ATOM   1331 N N   . PHE B 1 8   ? 28.548 -35.652 23.375 1.000 66.095  0 8   PHE B N   1 ? 
ATOM   1332 C CA  . PHE B 1 8   ? 28.231 -34.963 22.132 1.000 64.253  0 8   PHE B CA  1 ? 
ATOM   1333 C C   . PHE B 1 8   ? 26.994 -34.090 22.328 1.000 63.510  0 8   PHE B C   1 ? 
ATOM   1334 O O   . PHE B 1 8   ? 25.860 -34.465 21.996 1.000 61.665  0 8   PHE B O   1 ? 
ATOM   1335 C CB  . PHE B 1 8   ? 28.050 -35.967 20.982 1.000 74.456  0 8   PHE B CB  1 ? 
ATOM   1336 C CG  . PHE B 1 8   ? 28.058 -35.306 19.608 1.000 69.516  0 8   PHE B CG  1 ? 
ATOM   1337 C CD1 . PHE B 1 8   ? 29.260 -35.030 18.960 1.000 71.347  0 8   PHE B CD1 1 ? 
ATOM   1338 C CD2 . PHE B 1 8   ? 26.873 -34.922 18.988 1.000 71.577  0 8   PHE B CD2 1 ? 
ATOM   1339 C CE1 . PHE B 1 8   ? 29.275 -34.385 17.727 1.000 74.583  0 8   PHE B CE1 1 ? 
ATOM   1340 C CE2 . PHE B 1 8   ? 26.896 -34.298 17.743 1.000 81.480  0 8   PHE B CE2 1 ? 
ATOM   1341 C CZ  . PHE B 1 8   ? 28.093 -34.021 17.119 1.000 73.577  0 8   PHE B CZ  1 ? 
ATOM   1342 N N   . GLY B 1 9   ? 27.227 -32.901 22.863 1.000 61.779  0 9   GLY B N   1 ? 
ATOM   1343 C CA  . GLY B 1 9   ? 26.157 -31.927 23.006 1.000 69.491  0 9   GLY B CA  1 ? 
ATOM   1344 C C   . GLY B 1 9   ? 25.895 -31.171 21.706 1.000 69.230  0 9   GLY B C   1 ? 
ATOM   1345 O O   . GLY B 1 9   ? 26.779 -30.485 21.201 1.000 71.052  0 9   GLY B O   1 ? 
ATOM   1346 N N   . ALA B 1 10  ? 24.662 -31.282 21.198 1.000 78.305  0 10  ALA B N   1 ? 
ATOM   1347 C CA  . ALA B 1 10  ? 24.257 -30.693 19.928 1.000 78.488  0 10  ALA B CA  1 ? 
ATOM   1348 C C   . ALA B 1 10  ? 22.752 -30.816 19.771 1.000 76.688  0 10  ALA B C   1 ? 
ATOM   1349 O O   . ALA B 1 10  ? 22.230 -31.919 19.937 1.000 76.089  0 10  ALA B O   1 ? 
ATOM   1350 C CB  . ALA B 1 10  ? 24.898 -31.425 18.778 1.000 75.412  0 10  ALA B CB  1 ? 
ATOM   1351 N N   . GLY B 1 11  ? 22.097 -29.716 19.377 1.000 74.143  0 11  GLY B N   1 ? 
ATOM   1352 C CA  . GLY B 1 11  ? 20.713 -29.769 18.929 1.000 87.548  0 11  GLY B CA  1 ? 
ATOM   1353 C C   . GLY B 1 11  ? 20.551 -30.604 17.656 1.000 89.863  0 11  GLY B C   1 ? 
ATOM   1354 O O   . GLY B 1 11  ? 21.512 -30.810 16.907 1.000 86.442  0 11  GLY B O   1 ? 
ATOM   1355 N N   . TRP B 1 12  ? 19.314 -31.054 17.400 1.000 86.950  0 12  TRP B N   1 ? 
ATOM   1356 C CA  . TRP B 1 12  ? 19.023 -31.844 16.210 1.000 85.803  0 12  TRP B CA  1 ? 
ATOM   1357 C C   . TRP B 1 12  ? 17.669 -31.460 15.605 1.000 85.191  0 12  TRP B C   1 ? 
ATOM   1358 O O   . TRP B 1 12  ? 17.034 -32.309 14.980 1.000 68.424  0 12  TRP B O   1 ? 
ATOM   1359 C CB  . TRP B 1 12  ? 19.088 -33.344 16.526 1.000 81.434  0 12  TRP B CB  1 ? 
ATOM   1360 C CG  . TRP B 1 12  ? 18.152 -33.824 17.605 1.000 98.275  0 12  TRP B CG  1 ? 
ATOM   1361 C CD1 . TRP B 1 12  ? 16.812 -34.058 17.489 1.000 98.975  0 12  TRP B CD1 1 ? 
ATOM   1362 C CD2 . TRP B 1 12  ? 18.498 -34.152 18.971 1.000 103.002 0 12  TRP B CD2 1 ? 
ATOM   1363 N NE1 . TRP B 1 12  ? 16.304 -34.509 18.678 1.000 101.349 0 12  TRP B NE1 1 ? 
ATOM   1364 C CE2 . TRP B 1 12  ? 17.308 -34.573 19.608 1.000 104.128 0 12  TRP B CE2 1 ? 
ATOM   1365 C CE3 . TRP B 1 12  ? 19.679 -34.117 19.721 1.000 95.714  0 12  TRP B CE3 1 ? 
ATOM   1366 C CZ2 . TRP B 1 12  ? 17.275 -34.968 20.947 1.000 96.788  0 12  TRP B CZ2 1 ? 
ATOM   1367 C CZ3 . TRP B 1 12  ? 19.641 -34.493 21.049 1.000 104.524 0 12  TRP B CZ3 1 ? 
ATOM   1368 C CH2 . TRP B 1 12  ? 18.457 -34.922 21.650 1.000 95.047  0 12  TRP B CH2 1 ? 
ATOM   1369 N N   . PHE B 1 13  ? 17.296 -30.169 15.710 1.000 74.724  0 13  PHE B N   1 ? 
ATOM   1370 C CA  . PHE B 1 13  ? 15.920 -29.712 15.511 1.000 84.219  0 13  PHE B CA  1 ? 
ATOM   1371 C C   . PHE B 1 13  ? 15.762 -28.792 14.301 1.000 90.937  0 13  PHE B C   1 ? 
ATOM   1372 O O   . PHE B 1 13  ? 14.646 -28.367 14.028 1.000 110.358 0 13  PHE B O   1 ? 
ATOM   1373 C CB  . PHE B 1 13  ? 15.390 -28.920 16.719 1.000 78.365  0 13  PHE B CB  1 ? 
ATOM   1374 C CG  . PHE B 1 13  ? 15.539 -29.692 18.023 1.000 80.057  0 13  PHE B CG  1 ? 
ATOM   1375 C CD1 . PHE B 1 13  ? 14.821 -30.874 18.230 1.000 81.921  0 13  PHE B CD1 1 ? 
ATOM   1376 C CD2 . PHE B 1 13  ? 16.432 -29.268 19.011 1.000 78.898  0 13  PHE B CD2 1 ? 
ATOM   1377 C CE1 . PHE B 1 13  ? 14.986 -31.614 19.396 1.000 85.922  0 13  PHE B CE1 1 ? 
ATOM   1378 C CE2 . PHE B 1 13  ? 16.597 -30.007 20.174 1.000 86.276  0 13  PHE B CE2 1 ? 
ATOM   1379 C CZ  . PHE B 1 13  ? 15.871 -31.178 20.370 1.000 88.825  0 13  PHE B CZ  1 ? 
ATOM   1380 N N   . THR B 1 14  ? 16.866 -28.447 13.621 1.000 93.570  0 14  THR B N   1 ? 
ATOM   1381 C CA  . THR B 1 14  ? 16.849 -27.599 12.439 1.000 83.558  0 14  THR B CA  1 ? 
ATOM   1382 C C   . THR B 1 14  ? 17.869 -28.133 11.433 1.000 85.281  0 14  THR B C   1 ? 
ATOM   1383 O O   . THR B 1 14  ? 18.599 -29.090 11.713 1.000 79.010  0 14  THR B O   1 ? 
ATOM   1384 C CB  . THR B 1 14  ? 17.170 -26.147 12.800 1.000 79.292  0 14  THR B CB  1 ? 
ATOM   1385 O OG1 . THR B 1 14  ? 18.552 -26.127 13.130 1.000 74.361  0 14  THR B OG1 1 ? 
ATOM   1386 C CG2 . THR B 1 14  ? 16.352 -25.599 13.955 1.000 88.411  0 14  THR B CG2 1 ? 
ATOM   1387 N N   . ASP B 1 15  ? 17.928 -27.464 10.272 1.000 83.777  0 15  ASP B N   1 ? 
ATOM   1388 C CA  . ASP B 1 15  ? 18.832 -27.821 9.192  1.000 71.518  0 15  ASP B CA  1 ? 
ATOM   1389 C C   . ASP B 1 15  ? 20.252 -27.423 9.570  1.000 73.697  0 15  ASP B C   1 ? 
ATOM   1390 O O   . ASP B 1 15  ? 21.185 -28.197 9.359  1.000 71.269  0 15  ASP B O   1 ? 
ATOM   1391 C CB  . ASP B 1 15  ? 18.445 -27.143 7.885  1.000 69.591  0 15  ASP B CB  1 ? 
ATOM   1392 C CG  . ASP B 1 15  ? 17.178 -27.680 7.240  1.000 75.589  0 15  ASP B CG  1 ? 
ATOM   1393 O OD1 . ASP B 1 15  ? 16.958 -28.897 7.358  1.000 71.145  0 15  ASP B OD1 1 ? 
ATOM   1394 O OD2 . ASP B 1 15  ? 16.466 -26.897 6.581  1.000 66.350  0 15  ASP B OD2 1 ? 
ATOM   1395 N N   . ARG B 1 16  ? 20.401 -26.203 10.102 1.000 65.555  0 16  ARG B N   1 ? 
ATOM   1396 C CA  . ARG B 1 16  ? 21.719 -25.721 10.476 1.000 73.621  0 16  ARG B CA  1 ? 
ATOM   1397 C C   . ARG B 1 16  ? 22.265 -26.640 11.571 1.000 71.781  0 16  ARG B C   1 ? 
ATOM   1398 O O   . ARG B 1 16  ? 23.422 -27.049 11.503 1.000 76.727  0 16  ARG B O   1 ? 
ATOM   1399 C CB  . ARG B 1 16  ? 21.662 -24.224 10.820 1.000 73.295  0 16  ARG B CB  1 ? 
ATOM   1400 C CG  . ARG B 1 16  ? 21.111 -23.420 9.655  1.000 82.183  0 16  ARG B CG  1 ? 
ATOM   1401 C CD  . ARG B 1 16  ? 20.716 -22.009 10.005 1.000 80.369  0 16  ARG B CD  1 ? 
ATOM   1402 N NE  . ARG B 1 16  ? 21.919 -21.249 10.342 1.000 80.385  0 16  ARG B NE  1 ? 
ATOM   1403 C CZ  . ARG B 1 16  ? 21.897 -20.054 10.879 1.000 78.071  0 16  ARG B CZ  1 ? 
ATOM   1404 N NH1 . ARG B 1 16  ? 20.743 -19.441 11.042 1.000 84.313  0 16  ARG B NH1 1 ? 
ATOM   1405 N NH2 . ARG B 1 16  ? 23.022 -19.476 11.259 1.000 85.182  0 16  ARG B NH2 1 ? 
ATOM   1406 N N   . GLN B 1 17  ? 21.404 -27.021 12.533 1.000 75.993  0 17  GLN B N   1 ? 
ATOM   1407 C CA  . GLN B 1 17  ? 21.813 -27.865 13.650 1.000 77.143  0 17  GLN B CA  1 ? 
ATOM   1408 C C   . GLN B 1 17  ? 22.309 -29.210 13.133 1.000 74.167  0 17  GLN B C   1 ? 
ATOM   1409 O O   . GLN B 1 17  ? 23.347 -29.706 13.583 1.000 74.136  0 17  GLN B O   1 ? 
ATOM   1410 C CB  . GLN B 1 17  ? 20.702 -28.038 14.692 1.000 71.431  0 17  GLN B CB  1 ? 
ATOM   1411 C CG  . GLN B 1 17  ? 20.568 -26.829 15.617 1.000 71.992  0 17  GLN B CG  1 ? 
ATOM   1412 C CD  . GLN B 1 17  ? 19.432 -26.930 16.614 1.000 81.846  0 17  GLN B CD  1 ? 
ATOM   1413 O OE1 . GLN B 1 17  ? 18.775 -27.973 16.747 1.000 78.642  0 17  GLN B OE1 1 ? 
ATOM   1414 N NE2 . GLN B 1 17  ? 19.219 -25.846 17.351 1.000 73.148  0 17  GLN B NE2 1 ? 
ATOM   1415 N N   . ASN B 1 18  ? 21.568 -29.784 12.176 1.000 79.035  0 18  ASN B N   1 ? 
ATOM   1416 C CA  . ASN B 1 18  ? 21.898 -31.107 11.669 1.000 82.300  0 18  ASN B CA  1 ? 
ATOM   1417 C C   . ASN B 1 18  ? 23.165 -31.049 10.819 1.000 77.493  0 18  ASN B C   1 ? 
ATOM   1418 O O   . ASN B 1 18  ? 23.962 -31.986 10.814 1.000 68.926  0 18  ASN B O   1 ? 
ATOM   1419 C CB  . ASN B 1 18  ? 20.717 -31.749 10.955 1.000 88.286  0 18  ASN B CB  1 ? 
ATOM   1420 C CG  . ASN B 1 18  ? 19.681 -32.255 11.933 1.000 88.509  0 18  ASN B CG  1 ? 
ATOM   1421 O OD1 . ASN B 1 18  ? 20.020 -32.904 12.934 1.000 81.455  0 18  ASN B OD1 1 ? 
ATOM   1422 N ND2 . ASN B 1 18  ? 18.418 -31.965 11.656 1.000 85.191  0 18  ASN B ND2 1 ? 
ATOM   1423 N N   . LYS B 1 19  ? 23.367 -29.937 10.115 1.000 76.766  0 19  LYS B N   1 ? 
ATOM   1424 C CA  . LYS B 1 19  ? 24.558 -29.798 9.298  1.000 83.613  0 19  LYS B CA  1 ? 
ATOM   1425 C C   . LYS B 1 19  ? 25.775 -29.786 10.219 1.000 80.560  0 19  LYS B C   1 ? 
ATOM   1426 O O   . LYS B 1 19  ? 26.706 -30.560 10.017 1.000 73.909  0 19  LYS B O   1 ? 
ATOM   1427 C CB  . LYS B 1 19  ? 24.449 -28.542 8.428  1.000 87.022  0 19  LYS B CB  1 ? 
ATOM   1428 C CG  . LYS B 1 19  ? 25.552 -28.370 7.408  1.000 94.111  0 19  LYS B CG  1 ? 
ATOM   1429 C CD  . LYS B 1 19  ? 25.507 -27.045 6.658  1.000 90.713  0 19  LYS B CD  1 ? 
ATOM   1430 C CE  . LYS B 1 19  ? 26.696 -26.933 5.755  1.000 98.243  0 19  LYS B CE  1 ? 
ATOM   1431 N NZ  . LYS B 1 19  ? 26.722 -25.651 5.055  1.000 99.252  0 19  LYS B NZ  1 ? 
ATOM   1432 N N   . ALA B 1 20  ? 25.742 -28.905 11.229 1.000 75.641  0 20  ALA B N   1 ? 
ATOM   1433 C CA  . ALA B 1 20  ? 26.831 -28.752 12.187 1.000 64.234  0 20  ALA B CA  1 ? 
ATOM   1434 C C   . ALA B 1 20  ? 27.073 -30.047 12.959 1.000 63.113  0 20  ALA B C   1 ? 
ATOM   1435 O O   . ALA B 1 20  ? 28.204 -30.453 13.178 1.000 64.823  0 20  ALA B O   1 ? 
ATOM   1436 C CB  . ALA B 1 20  ? 26.513 -27.616 13.118 1.000 64.785  0 20  ALA B CB  1 ? 
ATOM   1437 N N   . TYR B 1 21  ? 25.993 -30.731 13.329 1.000 68.672  0 21  TYR B N   1 ? 
ATOM   1438 C CA  . TYR B 1 21  ? 26.083 -32.034 13.963 1.000 64.991  0 21  TYR B CA  1 ? 
ATOM   1439 C C   . TYR B 1 21  ? 26.948 -32.976 13.128 1.000 71.046  0 21  TYR B C   1 ? 
ATOM   1440 O O   . TYR B 1 21  ? 27.891 -33.587 13.661 1.000 58.453  0 21  TYR B O   1 ? 
ATOM   1441 C CB  . TYR B 1 21  ? 24.634 -32.502 14.152 1.000 71.842  0 21  TYR B CB  1 ? 
ATOM   1442 C CG  . TYR B 1 21  ? 24.464 -33.812 14.905 1.000 67.609  0 21  TYR B CG  1 ? 
ATOM   1443 C CD1 . TYR B 1 21  ? 24.998 -35.004 14.422 1.000 66.162  0 21  TYR B CD1 1 ? 
ATOM   1444 C CD2 . TYR B 1 21  ? 23.731 -33.857 16.087 1.000 75.290  0 21  TYR B CD2 1 ? 
ATOM   1445 C CE1 . TYR B 1 21  ? 24.844 -36.195 15.116 1.000 75.732  0 21  TYR B CE1 1 ? 
ATOM   1446 C CE2 . TYR B 1 21  ? 23.562 -35.048 16.783 1.000 61.084  0 21  TYR B CE2 1 ? 
ATOM   1447 C CZ  . TYR B 1 21  ? 24.118 -36.216 16.302 1.000 74.049  0 21  TYR B CZ  1 ? 
ATOM   1448 O OH  . TYR B 1 21  ? 23.931 -37.364 17.019 1.000 75.392  0 21  TYR B OH  1 ? 
ATOM   1449 N N   . LYS B 1 22  ? 26.596 -33.122 11.830 1.000 80.350  0 22  LYS B N   1 ? 
ATOM   1450 C CA  . LYS B 1 22  ? 27.243 -34.100 10.955 1.000 75.085  0 22  LYS B CA  1 ? 
ATOM   1451 C C   . LYS B 1 22  ? 28.712 -33.714 10.783 1.000 71.582  0 22  LYS B C   1 ? 
ATOM   1452 O O   . LYS B 1 22  ? 29.567 -34.593 10.851 1.000 74.477  0 22  LYS B O   1 ? 
ATOM   1453 C CB  . LYS B 1 22  ? 26.539 -34.302 9.603  1.000 69.741  0 22  LYS B CB  1 ? 
ATOM   1454 N N   . GLU B 1 23  ? 28.972 -32.403 10.597 1.000 61.323  0 23  GLU B N   1 ? 
ATOM   1455 C CA  . GLU B 1 23  ? 30.316 -31.867 10.452 1.000 64.856  0 23  GLU B CA  1 ? 
ATOM   1456 C C   . GLU B 1 23  ? 31.152 -32.159 11.692 1.000 69.700  0 23  GLU B C   1 ? 
ATOM   1457 O O   . GLU B 1 23  ? 32.313 -32.542 11.596 1.000 72.226  0 23  GLU B O   1 ? 
ATOM   1458 C CB  . GLU B 1 23  ? 30.309 -30.349 10.255 1.000 72.262  0 23  GLU B CB  1 ? 
ATOM   1459 C CG  . GLU B 1 23  ? 29.871 -29.873 8.870  1.000 77.606  0 23  GLU B CG  1 ? 
ATOM   1460 C CD  . GLU B 1 23  ? 29.888 -28.358 8.663  1.000 89.863  0 23  GLU B CD  1 ? 
ATOM   1461 O OE1 . GLU B 1 23  ? 29.655 -27.986 7.493  1.000 99.615  0 23  GLU B OE1 1 ? 
ATOM   1462 O OE2 . GLU B 1 23  ? 30.130 -27.541 9.602  1.000 93.740  0 23  GLU B OE2 1 ? 
ATOM   1463 N N   . ALA B 1 24  ? 30.557 -31.971 12.871 1.000 70.344  0 24  ALA B N   1 ? 
ATOM   1464 C CA  . ALA B 1 24  ? 31.291 -32.108 14.117 1.000 68.483  0 24  ALA B CA  1 ? 
ATOM   1465 C C   . ALA B 1 24  ? 31.658 -33.568 14.340 1.000 59.194  0 24  ALA B C   1 ? 
ATOM   1466 O O   . ALA B 1 24  ? 32.743 -33.861 14.830 1.000 62.186  0 24  ALA B O   1 ? 
ATOM   1467 C CB  . ALA B 1 24  ? 30.478 -31.550 15.285 1.000 69.579  0 24  ALA B CB  1 ? 
ATOM   1468 N N   . MET B 1 25  ? 30.746 -34.475 13.981 1.000 65.979  0 25  MET B N   1 ? 
ATOM   1469 C CA  . MET B 1 25  ? 30.998 -35.897 14.123 1.000 70.315  0 25  MET B CA  1 ? 
ATOM   1470 C C   . MET B 1 25  ? 32.153 -36.294 13.199 1.000 84.362  0 25  MET B C   1 ? 
ATOM   1471 O O   . MET B 1 25  ? 33.040 -37.020 13.629 1.000 80.259  0 25  MET B O   1 ? 
ATOM   1472 C CB  . MET B 1 25  ? 29.728 -36.702 13.828 1.000 76.306  0 25  MET B CB  1 ? 
ATOM   1473 C CG  . MET B 1 25  ? 29.741 -38.107 14.412 1.000 87.239  0 25  MET B CG  1 ? 
ATOM   1474 S SD  . MET B 1 25  ? 29.738 -38.174 16.219 1.000 82.376  0 25  MET B SD  1 ? 
ATOM   1475 C CE  . MET B 1 25  ? 28.018 -37.719 16.478 1.000 93.305  0 25  MET B CE  1 ? 
ATOM   1476 N N   . GLU B 1 26  ? 32.159 -35.797 11.951 1.000 82.910  0 26  GLU B N   1 ? 
ATOM   1477 C CA  . GLU B 1 26  ? 33.206 -36.123 10.986 1.000 80.306  0 26  GLU B CA  1 ? 
ATOM   1478 C C   . GLU B 1 26  ? 34.548 -35.599 11.487 1.000 83.919  0 26  GLU B C   1 ? 
ATOM   1479 O O   . GLU B 1 26  ? 35.556 -36.300 11.414 1.000 81.051  0 26  GLU B O   1 ? 
ATOM   1480 C CB  . GLU B 1 26  ? 32.991 -35.493 9.608  1.000 82.842  0 26  GLU B CB  1 ? 
ATOM   1481 C CG  . GLU B 1 26  ? 31.955 -36.186 8.723  1.000 102.303 0 26  GLU B CG  1 ? 
ATOM   1482 C CD  . GLU B 1 26  ? 31.539 -35.349 7.513  1.000 106.427 0 26  GLU B CD  1 ? 
ATOM   1483 O OE1 . GLU B 1 26  ? 31.592 -34.104 7.597  1.000 88.908  0 26  GLU B OE1 1 ? 
ATOM   1484 O OE2 . GLU B 1 26  ? 31.171 -35.920 6.463  1.000 113.633 0 26  GLU B OE2 1 ? 
ATOM   1485 N N   . ALA B 1 27  ? 34.549 -34.359 12.000 1.000 75.874  0 27  ALA B N   1 ? 
ATOM   1486 C CA  . ALA B 1 27  ? 35.758 -33.775 12.552 1.000 71.467  0 27  ALA B CA  1 ? 
ATOM   1487 C C   . ALA B 1 27  ? 36.299 -34.654 13.676 1.000 69.837  0 27  ALA B C   1 ? 
ATOM   1488 O O   . ALA B 1 27  ? 37.496 -34.905 13.738 1.000 76.808  0 27  ALA B O   1 ? 
ATOM   1489 C CB  . ALA B 1 27  ? 35.512 -32.353 13.014 1.000 74.849  0 27  ALA B CB  1 ? 
ATOM   1490 N N   . LEU B 1 28  ? 35.412 -35.168 14.534 1.000 68.209  0 28  LEU B N   1 ? 
ATOM   1491 C CA  . LEU B 1 28  ? 35.843 -35.937 15.696 1.000 75.938  0 28  LEU B CA  1 ? 
ATOM   1492 C C   . LEU B 1 28  ? 36.493 -37.259 15.282 1.000 75.411  0 28  LEU B C   1 ? 
ATOM   1493 O O   . LEU B 1 28  ? 37.425 -37.721 15.946 1.000 78.924  0 28  LEU B O   1 ? 
ATOM   1494 C CB  . LEU B 1 28  ? 34.677 -36.179 16.659 1.000 73.482  0 28  LEU B CB  1 ? 
ATOM   1495 C CG  . LEU B 1 28  ? 34.206 -34.971 17.482 1.000 77.306  0 28  LEU B CG  1 ? 
ATOM   1496 C CD1 . LEU B 1 28  ? 32.935 -35.340 18.254 1.000 77.896  0 28  LEU B CD1 1 ? 
ATOM   1497 C CD2 . LEU B 1 28  ? 35.286 -34.459 18.425 1.000 69.166  0 28  LEU B CD2 1 ? 
ATOM   1498 N N   . LYS B 1 29  ? 35.973 -37.900 14.225 1.000 83.242  0 29  LYS B N   1 ? 
ATOM   1499 C CA  . LYS B 1 29  ? 36.510 -39.176 13.770 1.000 88.403  0 29  LYS B CA  1 ? 
ATOM   1500 C C   . LYS B 1 29  ? 37.955 -39.036 13.291 1.000 76.825  0 29  LYS B C   1 ? 
ATOM   1501 O O   . LYS B 1 29  ? 38.708 -40.004 13.360 1.000 77.752  0 29  LYS B O   1 ? 
ATOM   1502 C CB  . LYS B 1 29  ? 35.668 -39.759 12.634 1.000 92.412  0 29  LYS B CB  1 ? 
ATOM   1503 C CG  . LYS B 1 29  ? 34.289 -40.267 13.044 1.000 92.224  0 29  LYS B CG  1 ? 
ATOM   1504 C CD  . LYS B 1 29  ? 33.419 -40.665 11.857 1.000 98.988  0 29  LYS B CD  1 ? 
ATOM   1505 C CE  . LYS B 1 29  ? 31.958 -40.676 12.146 1.000 92.310  0 29  LYS B CE  1 ? 
ATOM   1506 N NZ  . LYS B 1 29  ? 31.215 -40.657 10.889 1.000 94.475  0 29  LYS B NZ  1 ? 
ATOM   1507 N N   . GLU B 1 30  ? 38.340 -37.830 12.849 1.000 75.975  0 30  GLU B N   1 ? 
ATOM   1508 C CA  . GLU B 1 30  ? 39.684 -37.574 12.347 1.000 89.105  0 30  GLU B CA  1 ? 
ATOM   1509 C C   . GLU B 1 30  ? 40.590 -37.004 13.437 1.000 83.336  0 30  GLU B C   1 ? 
ATOM   1510 O O   . GLU B 1 30  ? 41.771 -36.830 13.196 1.000 87.102  0 30  GLU B O   1 ? 
ATOM   1511 C CB  . GLU B 1 30  ? 39.631 -36.660 11.116 1.000 94.918  0 30  GLU B CB  1 ? 
ATOM   1512 C CG  . GLU B 1 30  ? 38.952 -37.298 9.902  1.000 83.718  0 30  GLU B CG  1 ? 
ATOM   1513 N N   . ASN B 1 31  ? 40.059 -36.731 14.635 1.000 92.494  0 31  ASN B N   1 ? 
ATOM   1514 C CA  . ASN B 1 31  ? 40.851 -36.167 15.722 1.000 76.834  0 31  ASN B CA  1 ? 
ATOM   1515 C C   . ASN B 1 31  ? 41.501 -37.294 16.513 1.000 72.326  0 31  ASN B C   1 ? 
ATOM   1516 O O   . ASN B 1 31  ? 40.824 -38.072 17.180 1.000 76.978  0 31  ASN B O   1 ? 
ATOM   1517 C CB  . ASN B 1 31  ? 40.019 -35.313 16.675 1.000 71.727  0 31  ASN B CB  1 ? 
ATOM   1518 C CG  . ASN B 1 31  ? 40.887 -34.577 17.667 1.000 64.204  0 31  ASN B CG  1 ? 
ATOM   1519 O OD1 . ASN B 1 31  ? 41.686 -35.203 18.380 1.000 67.332  0 31  ASN B OD1 1 ? 
ATOM   1520 N ND2 . ASN B 1 31  ? 40.756 -33.258 17.719 1.000 59.161  0 31  ASN B ND2 1 ? 
ATOM   1521 N N   . PRO B 1 32  ? 42.846 -37.408 16.511 1.000 72.584  0 32  PRO B N   1 ? 
ATOM   1522 C CA  . PRO B 1 32  ? 43.482 -38.555 17.157 1.000 77.980  0 32  PRO B CA  1 ? 
ATOM   1523 C C   . PRO B 1 32  ? 43.517 -38.543 18.685 1.000 73.043  0 32  PRO B C   1 ? 
ATOM   1524 O O   . PRO B 1 32  ? 43.995 -39.509 19.263 1.000 68.128  0 32  PRO B O   1 ? 
ATOM   1525 C CB  . PRO B 1 32  ? 44.908 -38.504 16.528 1.000 77.635  0 32  PRO B CB  1 ? 
ATOM   1526 C CG  . PRO B 1 32  ? 45.165 -37.025 16.280 1.000 67.931  0 32  PRO B CG  1 ? 
ATOM   1527 C CD  . PRO B 1 32  ? 43.809 -36.497 15.863 1.000 60.767  0 32  PRO B CD  1 ? 
ATOM   1528 N N   . THR B 1 33  ? 43.035 -37.468 19.335 1.000 76.059  0 33  THR B N   1 ? 
ATOM   1529 C CA  . THR B 1 33  ? 43.000 -37.420 20.797 1.000 75.828  0 33  THR B CA  1 ? 
ATOM   1530 C C   . THR B 1 33  ? 41.615 -37.803 21.336 1.000 71.445  0 33  THR B C   1 ? 
ATOM   1531 O O   . THR B 1 33  ? 41.387 -37.742 22.541 1.000 72.955  0 33  THR B O   1 ? 
ATOM   1532 C CB  . THR B 1 33  ? 43.435 -36.050 21.340 1.000 73.022  0 33  THR B CB  1 ? 
ATOM   1533 O OG1 . THR B 1 33  ? 42.565 -35.030 20.858 1.000 62.802  0 33  THR B OG1 1 ? 
ATOM   1534 C CG2 . THR B 1 33  ? 44.858 -35.670 20.965 1.000 70.657  0 33  THR B CG2 1 ? 
ATOM   1535 N N   . ILE B 1 34  ? 40.705 -38.241 20.460 1.000 71.437  0 34  ILE B N   1 ? 
ATOM   1536 C CA  . ILE B 1 34  ? 39.337 -38.534 20.854 1.000 77.460  0 34  ILE B CA  1 ? 
ATOM   1537 C C   . ILE B 1 34  ? 39.059 -40.029 20.723 1.000 74.174  0 34  ILE B C   1 ? 
ATOM   1538 O O   . ILE B 1 34  ? 39.308 -40.623 19.678 1.000 69.205  0 34  ILE B O   1 ? 
ATOM   1539 C CB  . ILE B 1 34  ? 38.363 -37.710 19.994 1.000 77.778  0 34  ILE B CB  1 ? 
ATOM   1540 C CG1 . ILE B 1 34  ? 38.334 -36.236 20.434 1.000 73.089  0 34  ILE B CG1 1 ? 
ATOM   1541 C CG2 . ILE B 1 34  ? 36.973 -38.347 19.983 1.000 84.303  0 34  ILE B CG2 1 ? 
ATOM   1542 C CD1 . ILE B 1 34  ? 37.915 -36.035 21.877 1.000 72.777  0 34  ILE B CD1 1 ? 
ATOM   1543 N N   . ASP B 1 35  ? 38.530 -40.620 21.795 1.000 72.323  0 35  ASP B N   1 ? 
ATOM   1544 C CA  . ASP B 1 35  ? 37.990 -41.964 21.737 1.000 70.443  0 35  ASP B CA  1 ? 
ATOM   1545 C C   . ASP B 1 35  ? 36.490 -41.834 21.536 1.000 71.933  0 35  ASP B C   1 ? 
ATOM   1546 O O   . ASP B 1 35  ? 35.733 -41.788 22.494 1.000 75.700  0 35  ASP B O   1 ? 
ATOM   1547 C CB  . ASP B 1 35  ? 38.420 -42.794 22.934 1.000 67.045  0 35  ASP B CB  1 ? 
ATOM   1548 C CG  . ASP B 1 35  ? 37.750 -44.156 23.083 1.000 71.155  0 35  ASP B CG  1 ? 
ATOM   1549 O OD1 . ASP B 1 35  ? 36.878 -44.477 22.240 1.000 67.708  0 35  ASP B OD1 1 ? 
ATOM   1550 O OD2 . ASP B 1 35  ? 38.081 -44.872 24.067 1.000 66.643  0 35  ASP B OD2 1 ? 
ATOM   1551 N N   . LEU B 1 36  ? 36.090 -41.774 20.269 1.000 66.985  0 36  LEU B N   1 ? 
ATOM   1552 C CA  . LEU B 1 36  ? 34.705 -41.562 19.897 1.000 72.039  0 36  LEU B CA  1 ? 
ATOM   1553 C C   . LEU B 1 36  ? 33.847 -42.780 20.201 1.000 75.150  0 36  LEU B C   1 ? 
ATOM   1554 O O   . LEU B 1 36  ? 32.650 -42.642 20.412 1.000 76.907  0 36  LEU B O   1 ? 
ATOM   1555 C CB  . LEU B 1 36  ? 34.609 -41.226 18.412 1.000 81.515  0 36  LEU B CB  1 ? 
ATOM   1556 C CG  . LEU B 1 36  ? 33.212 -40.833 17.924 1.000 81.036  0 36  LEU B CG  1 ? 
ATOM   1557 C CD1 . LEU B 1 36  ? 32.753 -39.623 18.732 1.000 76.750  0 36  LEU B CD1 1 ? 
ATOM   1558 C CD2 . LEU B 1 36  ? 33.202 -40.546 16.430 1.000 89.029  0 36  LEU B CD2 1 ? 
ATOM   1559 N N   . GLU B 1 37  ? 34.438 -43.975 20.188 1.000 75.785  0 37  GLU B N   1 ? 
ATOM   1560 C CA  . GLU B 1 37  ? 33.633 -45.169 20.324 1.000 77.970  0 37  GLU B CA  1 ? 
ATOM   1561 C C   . GLU B 1 37  ? 33.162 -45.326 21.765 1.000 74.225  0 37  GLU B C   1 ? 
ATOM   1562 O O   . GLU B 1 37  ? 32.152 -45.978 21.998 1.000 68.254  0 37  GLU B O   1 ? 
ATOM   1563 C CB  . GLU B 1 37  ? 34.368 -46.427 19.862 1.000 86.201  0 37  GLU B CB  1 ? 
ATOM   1564 C CG  . GLU B 1 37  ? 33.454 -47.399 19.116 1.000 95.917  0 37  GLU B CG  1 ? 
ATOM   1565 C CD  . GLU B 1 37  ? 33.014 -48.651 19.858 1.000 101.098 0 37  GLU B CD  1 ? 
ATOM   1566 O OE1 . GLU B 1 37  ? 33.685 -49.102 20.816 1.000 112.217 0 37  GLU B OE1 1 ? 
ATOM   1567 O OE2 . GLU B 1 37  ? 31.963 -49.173 19.448 1.000 95.212  0 37  GLU B OE2 1 ? 
ATOM   1568 N N   . ASN B 1 38  ? 33.920 -44.785 22.726 1.000 67.892  0 38  ASN B N   1 ? 
ATOM   1569 C CA  . ASN B 1 38  ? 33.558 -44.898 24.131 1.000 67.998  0 38  ASN B CA  1 ? 
ATOM   1570 C C   . ASN B 1 38  ? 32.946 -43.579 24.626 1.000 68.900  0 38  ASN B C   1 ? 
ATOM   1571 O O   . ASN B 1 38  ? 32.726 -43.401 25.826 1.000 65.382  0 38  ASN B O   1 ? 
ATOM   1572 C CB  . ASN B 1 38  ? 34.748 -45.357 24.962 1.000 69.739  0 38  ASN B CB  1 ? 
ATOM   1573 C CG  . ASN B 1 38  ? 35.191 -46.763 24.617 1.000 86.544  0 38  ASN B CG  1 ? 
ATOM   1574 O OD1 . ASN B 1 38  ? 36.402 -46.996 24.499 1.000 81.341  0 38  ASN B OD1 1 ? 
ATOM   1575 N ND2 . ASN B 1 38  ? 34.273 -47.717 24.509 1.000 71.677  0 38  ASN B ND2 1 ? 
ATOM   1576 N N   . SER B 1 39  ? 32.677 -42.663 23.685 1.000 63.197  0 39  SER B N   1 ? 
ATOM   1577 C CA  . SER B 1 39  ? 32.014 -41.408 23.962 1.000 65.996  0 39  SER B CA  1 ? 
ATOM   1578 C C   . SER B 1 39  ? 30.508 -41.613 24.035 1.000 66.898  0 39  SER B C   1 ? 
ATOM   1579 O O   . SER B 1 39  ? 30.000 -42.676 23.697 1.000 68.401  0 39  SER B O   1 ? 
ATOM   1580 C CB  . SER B 1 39  ? 32.376 -40.389 22.934 1.000 61.630  0 39  SER B CB  1 ? 
ATOM   1581 O OG  . SER B 1 39  ? 33.738 -39.990 23.082 1.000 63.791  0 39  SER B OG  1 ? 
ATOM   1582 N N   . TYR B 1 40  ? 29.804 -40.574 24.482 1.000 70.929  0 40  TYR B N   1 ? 
ATOM   1583 C CA  . TYR B 1 40  ? 28.366 -40.656 24.663 1.000 59.534  0 40  TYR B CA  1 ? 
ATOM   1584 C C   . TYR B 1 40  ? 27.717 -39.704 23.671 1.000 57.654  0 40  TYR B C   1 ? 
ATOM   1585 O O   . TYR B 1 40  ? 27.910 -38.486 23.725 1.000 61.316  0 40  TYR B O   1 ? 
ATOM   1586 C CB  . TYR B 1 40  ? 27.899 -40.333 26.092 1.000 60.077  0 40  TYR B CB  1 ? 
ATOM   1587 C CG  . TYR B 1 40  ? 26.397 -40.473 26.322 1.000 55.959  0 40  TYR B CG  1 ? 
ATOM   1588 C CD1 . TYR B 1 40  ? 25.531 -39.434 26.014 1.000 56.684  0 40  TYR B CD1 1 ? 
ATOM   1589 C CD2 . TYR B 1 40  ? 25.845 -41.638 26.868 1.000 57.610  0 40  TYR B CD2 1 ? 
ATOM   1590 C CE1 . TYR B 1 40  ? 24.161 -39.544 26.231 1.000 64.894  0 40  TYR B CE1 1 ? 
ATOM   1591 C CE2 . TYR B 1 40  ? 24.477 -41.761 27.090 1.000 60.110  0 40  TYR B CE2 1 ? 
ATOM   1592 C CZ  . TYR B 1 40  ? 23.637 -40.693 26.810 1.000 64.641  0 40  TYR B CZ  1 ? 
ATOM   1593 O OH  . TYR B 1 40  ? 22.293 -40.813 27.030 1.000 69.279  0 40  TYR B OH  1 ? 
ATOM   1594 N N   . VAL B 1 41  ? 26.934 -40.303 22.776 1.000 64.739  0 41  VAL B N   1 ? 
ATOM   1595 C CA  . VAL B 1 41  ? 26.179 -39.583 21.770 1.000 76.980  0 41  VAL B CA  1 ? 
ATOM   1596 C C   . VAL B 1 41  ? 24.711 -39.730 22.147 1.000 65.836  0 41  VAL B C   1 ? 
ATOM   1597 O O   . VAL B 1 41  ? 24.166 -40.834 22.073 1.000 69.479  0 41  VAL B O   1 ? 
ATOM   1598 C CB  . VAL B 1 41  ? 26.438 -40.139 20.351 1.000 77.488  0 41  VAL B CB  1 ? 
ATOM   1599 C CG1 . VAL B 1 41  ? 25.689 -39.325 19.295 1.000 69.644  0 41  VAL B CG1 1 ? 
ATOM   1600 C CG2 . VAL B 1 41  ? 27.927 -40.251 20.043 1.000 70.002  0 41  VAL B CG2 1 ? 
ATOM   1601 N N   . PRO B 1 42  ? 24.017 -38.651 22.554 1.000 58.929  0 42  PRO B N   1 ? 
ATOM   1602 C CA  . PRO B 1 42  ? 22.615 -38.793 22.948 1.000 71.603  0 42  PRO B CA  1 ? 
ATOM   1603 C C   . PRO B 1 42  ? 21.785 -39.622 21.966 1.000 76.174  0 42  PRO B C   1 ? 
ATOM   1604 O O   . PRO B 1 42  ? 21.167 -40.625 22.346 1.000 76.287  0 42  PRO B O   1 ? 
ATOM   1605 C CB  . PRO B 1 42  ? 22.164 -37.332 23.071 1.000 68.659  0 42  PRO B CB  1 ? 
ATOM   1606 C CG  . PRO B 1 42  ? 23.438 -36.621 23.532 1.000 67.230  0 42  PRO B CG  1 ? 
ATOM   1607 C CD  . PRO B 1 42  ? 24.546 -37.291 22.734 1.000 59.889  0 42  PRO B CD  1 ? 
ATOM   1608 N N   . LEU B 1 43  ? 21.824 -39.243 20.687 1.000 92.799  0 43  LEU B N   1 ? 
ATOM   1609 C CA  . LEU B 1 43  ? 20.900 -39.820 19.716 1.000 93.980  0 43  LEU B CA  1 ? 
ATOM   1610 C C   . LEU B 1 43  ? 21.123 -41.331 19.548 1.000 86.372  0 43  LEU B C   1 ? 
ATOM   1611 O O   . LEU B 1 43  ? 20.199 -42.028 19.149 1.000 90.317  0 43  LEU B O   1 ? 
ATOM   1612 C CB  . LEU B 1 43  ? 20.935 -39.056 18.390 1.000 97.756  0 43  LEU B CB  1 ? 
ATOM   1613 C CG  . LEU B 1 43  ? 19.713 -38.188 18.029 1.000 94.587  0 43  LEU B CG  1 ? 
ATOM   1614 C CD1 . LEU B 1 43  ? 18.896 -37.523 19.146 1.000 93.804  0 43  LEU B CD1 1 ? 
ATOM   1615 C CD2 . LEU B 1 43  ? 20.177 -37.079 17.085 1.000 89.252  0 43  LEU B CD2 1 ? 
ATOM   1616 N N   . ASP B 1 44  ? 22.297 -41.860 19.924 1.000 75.958  0 44  ASP B N   1 ? 
ATOM   1617 C CA  . ASP B 1 44  ? 22.551 -43.300 19.896 1.000 79.801  0 44  ASP B CA  1 ? 
ATOM   1618 C C   . ASP B 1 44  ? 22.296 -43.996 21.239 1.000 85.366  0 44  ASP B C   1 ? 
ATOM   1619 O O   . ASP B 1 44  ? 22.686 -45.150 21.422 1.000 74.340  0 44  ASP B O   1 ? 
ATOM   1620 C CB  . ASP B 1 44  ? 24.010 -43.607 19.600 1.000 90.701  0 44  ASP B CB  1 ? 
ATOM   1621 C CG  . ASP B 1 44  ? 24.557 -43.017 18.312 1.000 90.967  0 44  ASP B CG  1 ? 
ATOM   1622 O OD1 . ASP B 1 44  ? 23.750 -42.600 17.471 1.000 96.523  0 44  ASP B OD1 1 ? 
ATOM   1623 O OD2 . ASP B 1 44  ? 25.785 -42.930 18.191 1.000 100.993 0 44  ASP B OD2 1 ? 
ATOM   1624 N N   . ASN B 1 45  ? 21.668 -43.302 22.192 1.000 89.719  0 45  ASN B N   1 ? 
ATOM   1625 C CA  . ASN B 1 45  ? 21.509 -43.808 23.551 1.000 89.793  0 45  ASN B CA  1 ? 
ATOM   1626 C C   . ASN B 1 45  ? 20.074 -43.542 24.011 1.000 96.119  0 45  ASN B C   1 ? 
ATOM   1627 O O   . ASN B 1 45  ? 19.814 -43.142 25.149 1.000 91.739  0 45  ASN B O   1 ? 
ATOM   1628 C CB  . ASN B 1 45  ? 22.564 -43.187 24.461 1.000 82.317  0 45  ASN B CB  1 ? 
ATOM   1629 C CG  . ASN B 1 45  ? 23.926 -43.783 24.200 1.000 81.634  0 45  ASN B CG  1 ? 
ATOM   1630 O OD1 . ASN B 1 45  ? 24.754 -43.205 23.482 1.000 68.357  0 45  ASN B OD1 1 ? 
ATOM   1631 N ND2 . ASN B 1 45  ? 24.150 -44.974 24.727 1.000 68.124  0 45  ASN B ND2 1 ? 
ATOM   1632 N N   . GLN B 1 46  ? 19.137 -43.715 23.078 1.000 100.000 0 46  GLN B N   1 ? 
ATOM   1633 C CA  . GLN B 1 46  ? 17.731 -43.531 23.379 1.000 103.543 0 46  GLN B CA  1 ? 
ATOM   1634 C C   . GLN B 1 46  ? 17.304 -44.735 24.207 1.000 81.179  0 46  GLN B C   1 ? 
ATOM   1635 O O   . GLN B 1 46  ? 17.762 -45.835 23.940 1.000 74.822  0 46  GLN B O   1 ? 
ATOM   1636 C CB  . GLN B 1 46  ? 16.943 -43.415 22.078 1.000 114.203 0 46  GLN B CB  1 ? 
ATOM   1637 C CG  . GLN B 1 46  ? 17.358 -42.243 21.196 1.000 120.983 0 46  GLN B CG  1 ? 
ATOM   1638 C CD  . GLN B 1 46  ? 16.885 -42.409 19.769 1.000 123.780 0 46  GLN B CD  1 ? 
ATOM   1639 O OE1 . GLN B 1 46  ? 17.382 -43.272 19.033 1.000 119.905 0 46  GLN B OE1 1 ? 
ATOM   1640 N NE2 . GLN B 1 46  ? 15.911 -41.597 19.372 1.000 109.815 0 46  GLN B NE2 1 ? 
ATOM   1641 N N   . TYR B 1 47  ? 16.456 -44.502 25.206 1.000 73.802  0 47  TYR B N   1 ? 
ATOM   1642 C CA  . TYR B 1 47  ? 16.228 -45.500 26.236 1.000 79.045  0 47  TYR B CA  1 ? 
ATOM   1643 C C   . TYR B 1 47  ? 15.539 -46.710 25.609 1.000 75.323  0 47  TYR B C   1 ? 
ATOM   1644 O O   . TYR B 1 47  ? 14.511 -46.542 24.958 1.000 73.012  0 47  TYR B O   1 ? 
ATOM   1645 C CB  . TYR B 1 47  ? 15.379 -44.912 27.370 1.000 73.480  0 47  TYR B CB  1 ? 
ATOM   1646 C CG  . TYR B 1 47  ? 15.147 -45.847 28.554 1.000 71.335  0 47  TYR B CG  1 ? 
ATOM   1647 C CD1 . TYR B 1 47  ? 16.219 -46.413 29.248 1.000 74.407  0 47  TYR B CD1 1 ? 
ATOM   1648 C CD2 . TYR B 1 47  ? 13.853 -46.178 28.961 1.000 68.051  0 47  TYR B CD2 1 ? 
ATOM   1649 C CE1 . TYR B 1 47  ? 16.009 -47.274 30.314 1.000 70.826  0 47  TYR B CE1 1 ? 
ATOM   1650 C CE2 . TYR B 1 47  ? 13.634 -47.036 30.029 1.000 69.039  0 47  TYR B CE2 1 ? 
ATOM   1651 C CZ  . TYR B 1 47  ? 14.715 -47.564 30.719 1.000 61.510  0 47  TYR B CZ  1 ? 
ATOM   1652 O OH  . TYR B 1 47  ? 14.483 -48.422 31.755 1.000 80.470  0 47  TYR B OH  1 ? 
ATOM   1653 N N   . LYS B 1 48  ? 16.120 -47.900 25.829 1.000 81.707  0 48  LYS B N   1 ? 
ATOM   1654 C CA  . LYS B 1 48  ? 15.566 -49.178 25.388 1.000 91.062  0 48  LYS B CA  1 ? 
ATOM   1655 C C   . LYS B 1 48  ? 15.345 -49.146 23.871 1.000 94.462  0 48  LYS B C   1 ? 
ATOM   1656 O O   . LYS B 1 48  ? 14.380 -49.708 23.374 1.000 94.238  0 48  LYS B O   1 ? 
ATOM   1657 C CB  . LYS B 1 48  ? 14.322 -49.548 26.219 1.000 86.228  0 48  LYS B CB  1 ? 
ATOM   1658 C CG  . LYS B 1 48  ? 14.616 -49.873 27.705 1.000 96.037  0 48  LYS B CG  1 ? 
ATOM   1659 C CD  . LYS B 1 48  ? 13.630 -50.748 28.489 1.000 86.890  0 48  LYS B CD  1 ? 
ATOM   1660 N N   . GLY B 1 49  ? 16.219 -48.446 23.135 1.000 97.746  0 49  GLY B N   1 ? 
ATOM   1661 C CA  . GLY B 1 49  ? 16.152 -48.388 21.684 1.000 102.161 0 49  GLY B CA  1 ? 
ATOM   1662 C C   . GLY B 1 49  ? 14.885 -47.741 21.113 1.000 103.141 0 49  GLY B C   1 ? 
ATOM   1663 O O   . GLY B 1 49  ? 14.745 -47.675 19.895 1.000 109.966 0 49  GLY B O   1 ? 
ATOM   1664 N N   . ILE B 1 50  ? 13.970 -47.226 21.948 1.000 102.276 0 50  ILE B N   1 ? 
ATOM   1665 C CA  . ILE B 1 50  ? 12.660 -46.815 21.454 1.000 103.764 0 50  ILE B CA  1 ? 
ATOM   1666 C C   . ILE B 1 50  ? 12.797 -45.437 20.804 1.000 95.440  0 50  ILE B C   1 ? 
ATOM   1667 O O   . ILE B 1 50  ? 13.383 -44.531 21.389 1.000 91.853  0 50  ILE B O   1 ? 
ATOM   1668 C CB  . ILE B 1 50  ? 11.556 -46.881 22.541 1.000 106.591 0 50  ILE B CB  1 ? 
ATOM   1669 C CG1 . ILE B 1 50  ? 11.370 -45.584 23.333 1.000 111.851 0 50  ILE B CG1 1 ? 
ATOM   1670 C CG2 . ILE B 1 50  ? 11.740 -48.075 23.481 1.000 101.459 0 50  ILE B CG2 1 ? 
ATOM   1671 C CD1 . ILE B 1 50  ? 10.399 -44.600 22.699 1.000 113.950 0 50  ILE B CD1 1 ? 
ATOM   1672 N N   . ARG B 1 51  ? 12.251 -45.274 19.590 1.000 99.836  0 51  ARG B N   1 ? 
ATOM   1673 C CA  . ARG B 1 51  ? 12.511 -44.067 18.818 1.000 96.183  0 51  ARG B CA  1 ? 
ATOM   1674 C C   . ARG B 1 51  ? 11.313 -43.116 18.928 1.000 96.098  0 51  ARG B C   1 ? 
ATOM   1675 O O   . ARG B 1 51  ? 10.207 -43.405 18.457 1.000 94.442  0 51  ARG B O   1 ? 
ATOM   1676 C CB  . ARG B 1 51  ? 12.977 -44.419 17.398 1.000 96.418  0 51  ARG B CB  1 ? 
ATOM   1677 N N   . VAL B 1 52  ? 11.579 -41.954 19.538 1.000 102.332 0 52  VAL B N   1 ? 
ATOM   1678 C CA  . VAL B 1 52  ? 10.556 -41.002 19.948 1.000 107.627 0 52  VAL B CA  1 ? 
ATOM   1679 C C   . VAL B 1 52  ? 9.795  -40.459 18.738 1.000 104.727 0 52  VAL B C   1 ? 
ATOM   1680 O O   . VAL B 1 52  ? 8.680  -39.951 18.890 1.000 111.163 0 52  VAL B O   1 ? 
ATOM   1681 C CB  . VAL B 1 52  ? 11.166 -39.850 20.779 1.000 117.292 0 52  VAL B CB  1 ? 
ATOM   1682 C CG1 . VAL B 1 52  ? 12.676 -39.703 20.603 1.000 113.699 0 52  VAL B CG1 1 ? 
ATOM   1683 C CG2 . VAL B 1 52  ? 10.493 -38.510 20.496 1.000 121.930 0 52  VAL B CG2 1 ? 
ATOM   1684 N N   . ASP B 1 53  ? 10.426 -40.513 17.557 1.000 113.377 0 53  ASP B N   1 ? 
ATOM   1685 C CA  . ASP B 1 53  ? 9.812  -40.058 16.313 1.000 112.629 0 53  ASP B CA  1 ? 
ATOM   1686 C C   . ASP B 1 53  ? 8.767  -41.067 15.822 1.000 102.225 0 53  ASP B C   1 ? 
ATOM   1687 O O   . ASP B 1 53  ? 7.730  -40.672 15.289 1.000 90.213  0 53  ASP B O   1 ? 
ATOM   1688 C CB  . ASP B 1 53  ? 10.856 -39.700 15.259 1.000 111.444 0 53  ASP B CB  1 ? 
ATOM   1689 C CG  . ASP B 1 53  ? 12.115 -40.560 15.185 1.000 101.053 0 53  ASP B CG  1 ? 
ATOM   1690 O OD1 . ASP B 1 53  ? 12.016 -41.801 15.275 1.000 98.279  0 53  ASP B OD1 1 ? 
ATOM   1691 O OD2 . ASP B 1 53  ? 13.203 -39.978 15.043 1.000 104.644 0 53  ASP B OD2 1 ? 
ATOM   1692 N N   . GLU B 1 54  ? 9.011  -42.363 16.077 1.000 105.479 0 54  GLU B N   1 ? 
ATOM   1693 C CA  . GLU B 1 54  ? 8.141  -43.435 15.608 1.000 111.266 0 54  GLU B CA  1 ? 
ATOM   1694 C C   . GLU B 1 54  ? 7.005  -43.679 16.609 1.000 117.723 0 54  GLU B C   1 ? 
ATOM   1695 O O   . GLU B 1 54  ? 5.965  -44.222 16.222 1.000 88.881  0 54  GLU B O   1 ? 
ATOM   1696 C CB  . GLU B 1 54  ? 8.827  -44.799 15.440 1.000 119.876 0 54  GLU B CB  1 ? 
ATOM   1697 C CG  . GLU B 1 54  ? 10.358 -44.840 15.430 1.000 129.331 0 54  GLU B CG  1 ? 
ATOM   1698 C CD  . GLU B 1 54  ? 11.085 -45.130 14.122 1.000 127.341 0 54  GLU B CD  1 ? 
ATOM   1699 O OE1 . GLU B 1 54  ? 10.440 -45.036 13.054 1.000 102.466 0 54  GLU B OE1 1 ? 
ATOM   1700 O OE2 . GLU B 1 54  ? 12.294 -45.471 14.188 1.000 119.628 0 54  GLU B OE2 1 ? 
ATOM   1701 N N   . HIS B 1 55  ? 7.225  -43.349 17.899 1.000 116.683 0 55  HIS B N   1 ? 
ATOM   1702 C CA  . HIS B 1 55  ? 6.221  -43.573 18.929 1.000 96.768  0 55  HIS B CA  1 ? 
ATOM   1703 C C   . HIS B 1 55  ? 6.132  -42.343 19.832 1.000 96.435  0 55  HIS B C   1 ? 
ATOM   1704 O O   . HIS B 1 55  ? 6.541  -42.401 20.986 1.000 90.817  0 55  HIS B O   1 ? 
ATOM   1705 C CB  . HIS B 1 55  ? 6.523  -44.856 19.720 1.000 104.635 0 55  HIS B CB  1 ? 
ATOM   1706 C CG  . HIS B 1 55  ? 6.792  -46.101 18.913 1.000 115.760 0 55  HIS B CG  1 ? 
ATOM   1707 N ND1 . HIS B 1 55  ? 5.815  -46.907 18.360 1.000 108.590 0 55  HIS B ND1 1 ? 
ATOM   1708 C CD2 . HIS B 1 55  ? 7.969  -46.689 18.606 1.000 109.008 0 55  HIS B CD2 1 ? 
ATOM   1709 C CE1 . HIS B 1 55  ? 6.391  -47.917 17.720 1.000 113.457 0 55  HIS B CE1 1 ? 
ATOM   1710 N NE2 . HIS B 1 55  ? 7.700  -47.808 17.864 1.000 109.851 0 55  HIS B NE2 1 ? 
ATOM   1711 N N   . PRO B 1 56  ? 5.588  -41.200 19.345 1.000 93.398  0 56  PRO B N   1 ? 
ATOM   1712 C CA  . PRO B 1 56  ? 5.493  -39.967 20.142 1.000 94.630  0 56  PRO B CA  1 ? 
ATOM   1713 C C   . PRO B 1 56  ? 4.694  -40.019 21.448 1.000 100.681 0 56  PRO B C   1 ? 
ATOM   1714 O O   . PRO B 1 56  ? 4.614  -39.010 22.162 1.000 86.944  0 56  PRO B O   1 ? 
ATOM   1715 C CB  . PRO B 1 56  ? 4.827  -38.945 19.187 1.000 90.372  0 56  PRO B CB  1 ? 
ATOM   1716 C CG  . PRO B 1 56  ? 4.977  -39.530 17.807 1.000 102.034 0 56  PRO B CG  1 ? 
ATOM   1717 C CD  . PRO B 1 56  ? 5.050  -41.040 17.985 1.000 99.126  0 56  PRO B CD  1 ? 
ATOM   1718 N N   . GLU B 1 57  ? 4.035  -41.159 21.704 1.000 91.652  0 57  GLU B N   1 ? 
ATOM   1719 C CA  . GLU B 1 57  ? 3.248  -41.311 22.915 1.000 94.876  0 57  GLU B CA  1 ? 
ATOM   1720 C C   . GLU B 1 57  ? 4.183  -41.352 24.127 1.000 87.023  0 57  GLU B C   1 ? 
ATOM   1721 O O   . GLU B 1 57  ? 3.747  -41.033 25.220 1.000 75.492  0 57  GLU B O   1 ? 
ATOM   1722 C CB  . GLU B 1 57  ? 2.253  -42.475 22.883 1.000 90.582  0 57  GLU B CB  1 ? 
ATOM   1723 C CG  . GLU B 1 57  ? 2.870  -43.863 22.708 1.000 97.534  0 57  GLU B CG  1 ? 
ATOM   1724 C CD  . GLU B 1 57  ? 3.124  -44.349 21.289 1.000 86.027  0 57  GLU B CD  1 ? 
ATOM   1725 O OE1 . GLU B 1 57  ? 3.152  -43.541 20.343 1.000 73.285  0 57  GLU B OE1 1 ? 
ATOM   1726 O OE2 . GLU B 1 57  ? 3.261  -45.574 21.156 1.000 88.945  0 57  GLU B OE2 1 ? 
ATOM   1727 N N   . TYR B 1 58  ? 5.477  -41.639 23.932 1.000 83.060  0 58  TYR B N   1 ? 
ATOM   1728 C CA  . TYR B 1 58  ? 6.420  -41.679 25.038 1.000 81.424  0 58  TYR B CA  1 ? 
ATOM   1729 C C   . TYR B 1 58  ? 6.813  -40.280 25.548 1.000 76.423  0 58  TYR B C   1 ? 
ATOM   1730 O O   . TYR B 1 58  ? 7.458  -40.203 26.585 1.000 76.314  0 58  TYR B O   1 ? 
ATOM   1731 C CB  . TYR B 1 58  ? 7.586  -42.579 24.613 1.000 77.853  0 58  TYR B CB  1 ? 
ATOM   1732 C CG  . TYR B 1 58  ? 7.234  -44.062 24.570 1.000 84.467  0 58  TYR B CG  1 ? 
ATOM   1733 C CD1 . TYR B 1 58  ? 7.344  -44.848 25.712 1.000 93.042  0 58  TYR B CD1 1 ? 
ATOM   1734 C CD2 . TYR B 1 58  ? 6.791  -44.689 23.403 1.000 92.446  0 58  TYR B CD2 1 ? 
ATOM   1735 C CE1 . TYR B 1 58  ? 7.016  -46.195 25.704 1.000 94.712  0 58  TYR B CE1 1 ? 
ATOM   1736 C CE2 . TYR B 1 58  ? 6.466  -46.038 23.380 1.000 83.044  0 58  TYR B CE2 1 ? 
ATOM   1737 C CZ  . TYR B 1 58  ? 6.565  -46.791 24.538 1.000 91.590  0 58  TYR B CZ  1 ? 
ATOM   1738 O OH  . TYR B 1 58  ? 6.256  -48.123 24.586 1.000 78.506  0 58  TYR B OH  1 ? 
ATOM   1739 N N   . LEU B 1 59  ? 6.361  -39.196 24.898 1.000 67.064  0 59  LEU B N   1 ? 
ATOM   1740 C CA  . LEU B 1 59  ? 6.593  -37.835 25.367 1.000 79.830  0 59  LEU B CA  1 ? 
ATOM   1741 C C   . LEU B 1 59  ? 5.608  -37.409 26.467 1.000 92.594  0 59  LEU B C   1 ? 
ATOM   1742 O O   . LEU B 1 59  ? 5.562  -36.232 26.876 1.000 75.809  0 59  LEU B O   1 ? 
ATOM   1743 C CB  . LEU B 1 59  ? 6.477  -36.913 24.151 1.000 78.848  0 59  LEU B CB  1 ? 
ATOM   1744 C CG  . LEU B 1 59  ? 7.486  -37.155 23.020 1.000 88.143  0 59  LEU B CG  1 ? 
ATOM   1745 C CD1 . LEU B 1 59  ? 7.330  -36.075 21.939 1.000 84.405  0 59  LEU B CD1 1 ? 
ATOM   1746 C CD2 . LEU B 1 59  ? 8.939  -37.249 23.507 1.000 75.366  0 59  LEU B CD2 1 ? 
ATOM   1747 N N   . HIS B 1 60  ? 4.779  -38.360 26.917 1.000 77.752  0 60  HIS B N   1 ? 
ATOM   1748 C CA  . HIS B 1 60  ? 3.919  -38.160 28.076 1.000 76.124  0 60  HIS B CA  1 ? 
ATOM   1749 C C   . HIS B 1 60  ? 4.234  -39.230 29.123 1.000 68.306  0 60  HIS B C   1 ? 
ATOM   1750 O O   . HIS B 1 60  ? 3.567  -39.310 30.141 1.000 67.934  0 60  HIS B O   1 ? 
ATOM   1751 C CB  . HIS B 1 60  ? 2.432  -38.181 27.673 1.000 79.152  0 60  HIS B CB  1 ? 
ATOM   1752 C CG  . HIS B 1 60  ? 1.933  -37.075 26.768 1.000 77.309  0 60  HIS B CG  1 ? 
ATOM   1753 N ND1 . HIS B 1 60  ? 1.359  -35.901 27.230 1.000 71.998  0 60  HIS B ND1 1 ? 
ATOM   1754 C CD2 . HIS B 1 60  ? 1.849  -37.020 25.413 1.000 73.491  0 60  HIS B CD2 1 ? 
ATOM   1755 C CE1 . HIS B 1 60  ? 1.014  -35.136 26.198 1.000 71.292  0 60  HIS B CE1 1 ? 
ATOM   1756 N NE2 . HIS B 1 60  ? 1.304  -35.798 25.077 1.000 79.314  0 60  HIS B NE2 1 ? 
ATOM   1757 N N   . ASP B 1 61  ? 5.220  -40.086 28.835 1.000 60.176  0 61  ASP B N   1 ? 
ATOM   1758 C CA  . ASP B 1 61  ? 5.625  -41.152 29.732 1.000 65.570  0 61  ASP B CA  1 ? 
ATOM   1759 C C   . ASP B 1 61  ? 6.767  -40.633 30.602 1.000 71.492  0 61  ASP B C   1 ? 
ATOM   1760 O O   . ASP B 1 61  ? 7.833  -40.311 30.099 1.000 63.941  0 61  ASP B O   1 ? 
ATOM   1761 C CB  . ASP B 1 61  ? 6.014  -42.397 28.959 1.000 66.716  0 61  ASP B CB  1 ? 
ATOM   1762 C CG  . ASP B 1 61  ? 6.562  -43.523 29.810 1.000 66.058  0 61  ASP B CG  1 ? 
ATOM   1763 O OD1 . ASP B 1 61  ? 6.784  -43.303 31.011 1.000 82.043  0 61  ASP B OD1 1 ? 
ATOM   1764 O OD2 . ASP B 1 61  ? 6.760  -44.596 29.254 1.000 69.116  0 61  ASP B OD2 1 ? 
ATOM   1765 N N   . LYS B 1 62  ? 6.544  -40.595 31.919 1.000 64.345  0 62  LYS B N   1 ? 
ATOM   1766 C CA  . LYS B 1 62  ? 7.492  -40.033 32.873 1.000 59.957  0 62  LYS B CA  1 ? 
ATOM   1767 C C   . LYS B 1 62  ? 8.696  -40.951 33.084 1.000 55.480  0 62  LYS B C   1 ? 
ATOM   1768 O O   . LYS B 1 62  ? 9.775  -40.481 33.447 1.000 57.100  0 62  LYS B O   1 ? 
ATOM   1769 C CB  . LYS B 1 62  ? 6.751  -39.799 34.196 1.000 54.964  0 62  LYS B CB  1 ? 
ATOM   1770 C CG  . LYS B 1 62  ? 5.707  -38.721 34.105 1.000 56.490  0 62  LYS B CG  1 ? 
ATOM   1771 C CD  . LYS B 1 62  ? 4.877  -38.543 35.371 1.000 61.180  0 62  LYS B CD  1 ? 
ATOM   1772 C CE  . LYS B 1 62  ? 3.959  -37.359 35.272 1.000 63.302  0 62  LYS B CE  1 ? 
ATOM   1773 N NZ  . LYS B 1 62  ? 2.788  -37.595 34.431 1.000 61.982  0 62  LYS B NZ  1 ? 
ATOM   1774 N N   . VAL B 1 63  ? 8.497  -42.261 32.881 1.000 56.550  0 63  VAL B N   1 ? 
ATOM   1775 C CA  . VAL B 1 63  ? 9.566  -43.234 33.020 1.000 55.749  0 63  VAL B CA  1 ? 
ATOM   1776 C C   . VAL B 1 63  ? 10.555 -43.082 31.860 1.000 60.424  0 63  VAL B C   1 ? 
ATOM   1777 O O   . VAL B 1 63  ? 11.753 -43.004 32.075 1.000 60.423  0 63  VAL B O   1 ? 
ATOM   1778 C CB  . VAL B 1 63  ? 8.989  -44.655 33.136 1.000 60.439  0 63  VAL B CB  1 ? 
ATOM   1779 C CG1 . VAL B 1 63  ? 10.064 -45.738 33.142 1.000 61.946  0 63  VAL B CG1 1 ? 
ATOM   1780 C CG2 . VAL B 1 63  ? 8.105  -44.794 34.369 1.000 65.235  0 63  VAL B CG2 1 ? 
ATOM   1781 N N   . TRP B 1 64  ? 10.060 -43.020 30.628 1.000 64.355  0 64  TRP B N   1 ? 
ATOM   1782 C CA  . TRP B 1 64  ? 10.921 -42.758 29.485 1.000 59.308  0 64  TRP B CA  1 ? 
ATOM   1783 C C   . TRP B 1 64  ? 11.712 -41.471 29.716 1.000 57.295  0 64  TRP B C   1 ? 
ATOM   1784 O O   . TRP B 1 64  ? 12.920 -41.433 29.516 1.000 57.669  0 64  TRP B O   1 ? 
ATOM   1785 C CB  . TRP B 1 64  ? 10.109 -42.670 28.174 1.000 64.070  0 64  TRP B CB  1 ? 
ATOM   1786 C CG  . TRP B 1 64  ? 10.991 -42.338 27.003 1.000 69.642  0 64  TRP B CG  1 ? 
ATOM   1787 C CD1 . TRP B 1 64  ? 11.701 -43.220 26.240 1.000 60.299  0 64  TRP B CD1 1 ? 
ATOM   1788 C CD2 . TRP B 1 64  ? 11.350 -41.019 26.541 1.000 69.647  0 64  TRP B CD2 1 ? 
ATOM   1789 N NE1 . TRP B 1 64  ? 12.460 -42.542 25.324 1.000 69.350  0 64  TRP B NE1 1 ? 
ATOM   1790 C CE2 . TRP B 1 64  ? 12.271 -41.195 25.485 1.000 64.025  0 64  TRP B CE2 1 ? 
ATOM   1791 C CE3 . TRP B 1 64  ? 10.988 -39.724 26.915 1.000 66.275  0 64  TRP B CE3 1 ? 
ATOM   1792 C CZ2 . TRP B 1 64  ? 12.828 -40.120 24.809 1.000 60.726  0 64  TRP B CZ2 1 ? 
ATOM   1793 C CZ3 . TRP B 1 64  ? 11.533 -38.661 26.233 1.000 65.453  0 64  TRP B CZ3 1 ? 
ATOM   1794 C CH2 . TRP B 1 64  ? 12.465 -38.859 25.220 1.000 61.001  0 64  TRP B CH2 1 ? 
ATOM   1795 N N   . ALA B 1 65  ? 11.017 -40.404 30.137 1.000 54.681  0 65  ALA B N   1 ? 
ATOM   1796 C CA  . ALA B 1 65  ? 11.640 -39.106 30.329 1.000 49.635  0 65  ALA B CA  1 ? 
ATOM   1797 C C   . ALA B 1 65  ? 12.719 -39.155 31.411 1.000 59.005  0 65  ALA B C   1 ? 
ATOM   1798 O O   . ALA B 1 65  ? 13.820 -38.643 31.200 1.000 55.474  0 65  ALA B O   1 ? 
ATOM   1799 C CB  . ALA B 1 65  ? 10.568 -38.108 30.663 1.000 53.788  0 65  ALA B CB  1 ? 
ATOM   1800 N N   . THR B 1 66  ? 12.411 -39.817 32.547 1.000 56.535  0 66  THR B N   1 ? 
ATOM   1801 C CA  . THR B 1 66  ? 13.341 -39.934 33.658 1.000 54.003  0 66  THR B CA  1 ? 
ATOM   1802 C C   . THR B 1 66  ? 14.608 -40.646 33.206 1.000 59.033  0 66  THR B C   1 ? 
ATOM   1803 O O   . THR B 1 66  ? 15.712 -40.159 33.468 1.000 55.422  0 66  THR B O   1 ? 
ATOM   1804 C CB  . THR B 1 66  ? 12.691 -40.660 34.842 1.000 57.682  0 66  THR B CB  1 ? 
ATOM   1805 O OG1 . THR B 1 66  ? 11.683 -39.794 35.347 1.000 50.332  0 66  THR B OG1 1 ? 
ATOM   1806 C CG2 . THR B 1 66  ? 13.642 -40.901 36.000 1.000 56.176  0 66  THR B CG2 1 ? 
ATOM   1807 N N   . ALA B 1 67  ? 14.449 -41.813 32.565 1.000 53.238  0 67  ALA B N   1 ? 
ATOM   1808 C CA  . ALA B 1 67  ? 15.593 -42.636 32.183 1.000 57.929  0 67  ALA B CA  1 ? 
ATOM   1809 C C   . ALA B 1 67  ? 16.469 -41.921 31.154 1.000 53.074  0 67  ALA B C   1 ? 
ATOM   1810 O O   . ALA B 1 67  ? 17.697 -41.961 31.253 1.000 57.824  0 67  ALA B O   1 ? 
ATOM   1811 C CB  . ALA B 1 67  ? 15.137 -43.981 31.643 1.000 58.430  0 67  ALA B CB  1 ? 
ATOM   1812 N N   . THR B 1 68  ? 15.843 -41.245 30.194 1.000 52.625  0 68  THR B N   1 ? 
ATOM   1813 C CA  . THR B 1 68  ? 16.611 -40.571 29.154 1.000 63.364  0 68  THR B CA  1 ? 
ATOM   1814 C C   . THR B 1 68  ? 17.378 -39.409 29.771 1.000 56.128  0 68  THR B C   1 ? 
ATOM   1815 O O   . THR B 1 68  ? 18.549 -39.202 29.471 1.000 60.241  0 68  THR B O   1 ? 
ATOM   1816 C CB  . THR B 1 68  ? 15.736 -40.089 27.988 1.000 55.820  0 68  THR B CB  1 ? 
ATOM   1817 O OG1 . THR B 1 68  ? 14.859 -41.148 27.649 1.000 54.342  0 68  THR B OG1 1 ? 
ATOM   1818 C CG2 . THR B 1 68  ? 16.562 -39.749 26.761 1.000 56.393  0 68  THR B CG2 1 ? 
ATOM   1819 N N   . TYR B 1 69  ? 16.693 -38.622 30.602 1.000 65.801  0 69  TYR B N   1 ? 
ATOM   1820 C CA  . TYR B 1 69  ? 17.316 -37.473 31.245 1.000 55.039  0 69  TYR B CA  1 ? 
ATOM   1821 C C   . TYR B 1 69  ? 18.522 -37.952 32.036 1.000 57.733  0 69  TYR B C   1 ? 
ATOM   1822 O O   . TYR B 1 69  ? 19.605 -37.419 31.879 1.000 63.747  0 69  TYR B O   1 ? 
ATOM   1823 C CB  . TYR B 1 69  ? 16.294 -36.760 32.140 1.000 62.802  0 69  TYR B CB  1 ? 
ATOM   1824 C CG  . TYR B 1 69  ? 16.890 -35.671 33.021 1.000 53.674  0 69  TYR B CG  1 ? 
ATOM   1825 C CD1 . TYR B 1 69  ? 17.329 -34.475 32.468 1.000 57.091  0 69  TYR B CD1 1 ? 
ATOM   1826 C CD2 . TYR B 1 69  ? 17.017 -35.832 34.401 1.000 57.804  0 69  TYR B CD2 1 ? 
ATOM   1827 C CE1 . TYR B 1 69  ? 17.841 -33.454 33.255 1.000 55.099  0 69  TYR B CE1 1 ? 
ATOM   1828 C CE2 . TYR B 1 69  ? 17.586 -34.853 35.194 1.000 50.118  0 69  TYR B CE2 1 ? 
ATOM   1829 C CZ  . TYR B 1 69  ? 17.985 -33.654 34.619 1.000 53.361  0 69  TYR B CZ  1 ? 
ATOM   1830 O OH  . TYR B 1 69  ? 18.534 -32.686 35.389 1.000 50.913  0 69  TYR B OH  1 ? 
ATOM   1831 N N   . ASN B 1 70  ? 18.328 -38.992 32.850 1.000 52.566  0 70  ASN B N   1 ? 
ATOM   1832 C CA  . ASN B 1 70  ? 19.391 -39.534 33.671 1.000 55.605  0 70  ASN B CA  1 ? 
ATOM   1833 C C   . ASN B 1 70  ? 20.545 -40.068 32.829 1.000 65.608  0 70  ASN B C   1 ? 
ATOM   1834 O O   . ASN B 1 70  ? 21.709 -39.980 33.249 1.000 52.301  0 70  ASN B O   1 ? 
ATOM   1835 C CB  . ASN B 1 70  ? 18.844 -40.581 34.638 1.000 61.887  0 70  ASN B CB  1 ? 
ATOM   1836 C CG  . ASN B 1 70  ? 18.352 -39.915 35.901 1.000 62.827  0 70  ASN B CG  1 ? 
ATOM   1837 O OD1 . ASN B 1 70  ? 19.165 -39.576 36.762 1.000 79.687  0 70  ASN B OD1 1 ? 
ATOM   1838 N ND2 . ASN B 1 70  ? 17.054 -39.697 36.024 1.000 63.027  0 70  ASN B ND2 1 ? 
ATOM   1839 N N   . ASN B 1 71  ? 20.225 -40.637 31.660 1.000 64.107  0 71  ASN B N   1 ? 
ATOM   1840 C CA  . ASN B 1 71  ? 21.239 -41.244 30.803 1.000 61.089  0 71  ASN B CA  1 ? 
ATOM   1841 C C   . ASN B 1 71  ? 22.131 -40.155 30.208 1.000 54.243  0 71  ASN B C   1 ? 
ATOM   1842 O O   . ASN B 1 71  ? 23.341 -40.310 30.157 1.000 56.141  0 71  ASN B O   1 ? 
ATOM   1843 C CB  . ASN B 1 71  ? 20.586 -42.108 29.734 1.000 68.894  0 71  ASN B CB  1 ? 
ATOM   1844 C CG  . ASN B 1 71  ? 21.382 -43.334 29.383 1.000 71.614  0 71  ASN B CG  1 ? 
ATOM   1845 O OD1 . ASN B 1 71  ? 20.988 -44.031 28.450 1.000 83.542  0 71  ASN B OD1 1 ? 
ATOM   1846 N ND2 . ASN B 1 71  ? 22.511 -43.577 30.028 1.000 78.901  0 71  ASN B ND2 1 ? 
ATOM   1847 N N   . ASP B 1 72  ? 21.521 -39.039 29.792 1.000 51.124  0 72  ASP B N   1 ? 
ATOM   1848 C CA  . ASP B 1 72  ? 22.247 -37.860 29.362 1.000 46.715  0 72  ASP B CA  1 ? 
ATOM   1849 C C   . ASP B 1 72  ? 23.143 -37.327 30.480 1.000 64.158  0 72  ASP B C   1 ? 
ATOM   1850 O O   . ASP B 1 72  ? 24.317 -37.054 30.245 1.000 60.199  0 72  ASP B O   1 ? 
ATOM   1851 C CB  . ASP B 1 72  ? 21.290 -36.846 28.762 1.000 58.461  0 72  ASP B CB  1 ? 
ATOM   1852 C CG  . ASP B 1 72  ? 20.999 -37.065 27.279 1.000 68.976  0 72  ASP B CG  1 ? 
ATOM   1853 O OD1 . ASP B 1 72  ? 20.863 -38.253 26.857 1.000 80.064  0 72  ASP B OD1 1 ? 
ATOM   1854 O OD2 . ASP B 1 72  ? 20.959 -36.051 26.553 1.000 83.434  0 72  ASP B OD2 1 ? 
ATOM   1855 N N   . LEU B 1 73  ? 22.603 -37.191 31.704 1.000 55.820  0 73  LEU B N   1 ? 
ATOM   1856 C CA  . LEU B 1 73  ? 23.401 -36.681 32.793 1.000 55.413  0 73  LEU B CA  1 ? 
ATOM   1857 C C   . LEU B 1 73  ? 24.557 -37.650 33.018 1.000 54.144  0 73  LEU B C   1 ? 
ATOM   1858 O O   . LEU B 1 73  ? 25.697 -37.244 33.232 1.000 50.553  0 73  LEU B O   1 ? 
ATOM   1859 C CB  . LEU B 1 73  ? 22.578 -36.499 34.070 1.000 60.675  0 73  LEU B CB  1 ? 
ATOM   1860 C CG  . LEU B 1 73  ? 21.527 -35.381 34.068 1.000 58.400  0 73  LEU B CG  1 ? 
ATOM   1861 C CD1 . LEU B 1 73  ? 21.235 -34.940 35.493 1.000 61.793  0 73  LEU B CD1 1 ? 
ATOM   1862 C CD2 . LEU B 1 73  ? 21.862 -34.175 33.258 1.000 63.971  0 73  LEU B CD2 1 ? 
ATOM   1863 N N   . ASN B 1 74  ? 24.251 -38.938 32.980 1.000 53.420  0 74  ASN B N   1 ? 
ATOM   1864 C CA  . ASN B 1 74  ? 25.268 -39.961 33.167 1.000 54.714  0 74  ASN B CA  1 ? 
ATOM   1865 C C   . ASN B 1 74  ? 26.365 -39.905 32.097 1.000 47.925  0 74  ASN B C   1 ? 
ATOM   1866 O O   . ASN B 1 74  ? 27.557 -40.084 32.385 1.000 55.145  0 74  ASN B O   1 ? 
ATOM   1867 C CB  . ASN B 1 74  ? 24.601 -41.322 33.140 1.000 60.299  0 74  ASN B CB  1 ? 
ATOM   1868 C CG  . ASN B 1 74  ? 25.551 -42.356 33.667 1.000 66.191  0 74  ASN B CG  1 ? 
ATOM   1869 O OD1 . ASN B 1 74  ? 26.054 -43.182 32.902 1.000 76.781  0 74  ASN B OD1 1 ? 
ATOM   1870 N ND2 . ASN B 1 74  ? 25.846 -42.289 34.952 1.000 64.541  0 74  ASN B ND2 1 ? 
ATOM   1871 N N   . GLY B 1 75  ? 25.949 -39.651 30.858 1.000 50.739  0 75  GLY B N   1 ? 
ATOM   1872 C CA  . GLY B 1 75  ? 26.850 -39.500 29.719 1.000 54.199  0 75  GLY B CA  1 ? 
ATOM   1873 C C   . GLY B 1 75  ? 27.787 -38.310 29.906 1.000 58.803  0 75  GLY B C   1 ? 
ATOM   1874 O O   . GLY B 1 75  ? 28.941 -38.340 29.475 1.000 62.874  0 75  GLY B O   1 ? 
ATOM   1875 N N   . ILE B 1 76  ? 27.309 -37.243 30.562 1.000 61.670  0 76  ILE B N   1 ? 
ATOM   1876 C CA  . ILE B 1 76  ? 28.181 -36.108 30.817 1.000 52.864  0 76  ILE B CA  1 ? 
ATOM   1877 C C   . ILE B 1 76  ? 29.167 -36.431 31.928 1.000 50.474  0 76  ILE B C   1 ? 
ATOM   1878 O O   . ILE B 1 76  ? 30.382 -36.248 31.770 1.000 51.095  0 76  ILE B O   1 ? 
ATOM   1879 C CB  . ILE B 1 76  ? 27.401 -34.828 31.115 1.000 60.970  0 76  ILE B CB  1 ? 
ATOM   1880 C CG1 . ILE B 1 76  ? 26.547 -34.430 29.899 1.000 59.519  0 76  ILE B CG1 1 ? 
ATOM   1881 C CG2 . ILE B 1 76  ? 28.374 -33.722 31.546 1.000 55.037  0 76  ILE B CG2 1 ? 
ATOM   1882 C CD1 . ILE B 1 76  ? 25.489 -33.383 30.206 1.000 60.957  0 76  ILE B CD1 1 ? 
ATOM   1883 N N   . LYS B 1 77  ? 28.641 -36.965 33.031 1.000 52.056  0 77  LYS B N   1 ? 
ATOM   1884 C CA  . LYS B 1 77  ? 29.474 -37.135 34.211 1.000 53.397  0 77  LYS B CA  1 ? 
ATOM   1885 C C   . LYS B 1 77  ? 30.526 -38.224 34.004 1.000 55.165  0 77  LYS B C   1 ? 
ATOM   1886 O O   . LYS B 1 77  ? 31.603 -38.094 34.568 1.000 54.436  0 77  LYS B O   1 ? 
ATOM   1887 C CB  . LYS B 1 77  ? 28.673 -37.306 35.507 1.000 55.260  0 77  LYS B CB  1 ? 
ATOM   1888 C CG  . LYS B 1 77  ? 28.262 -38.723 35.847 1.000 55.301  0 77  LYS B CG  1 ? 
ATOM   1889 C CD  . LYS B 1 77  ? 27.188 -38.780 36.926 1.000 59.342  0 77  LYS B CD  1 ? 
ATOM   1890 C CE  . LYS B 1 77  ? 27.067 -40.188 37.389 1.000 57.017  0 77  LYS B CE  1 ? 
ATOM   1891 N NZ  . LYS B 1 77  ? 25.809 -40.446 38.087 1.000 64.620  0 77  LYS B NZ  1 ? 
ATOM   1892 N N   . THR B 1 78  ? 30.278 -39.248 33.173 1.000 64.882  0 78  THR B N   1 ? 
ATOM   1893 C CA  . THR B 1 78  ? 31.232 -40.351 33.060 1.000 60.102  0 78  THR B CA  1 ? 
ATOM   1894 C C   . THR B 1 78  ? 32.222 -40.144 31.919 1.000 60.679  0 78  THR B C   1 ? 
ATOM   1895 O O   . THR B 1 78  ? 33.027 -41.019 31.698 1.000 55.588  0 78  THR B O   1 ? 
ATOM   1896 C CB  . THR B 1 78  ? 30.511 -41.677 32.884 1.000 60.224  0 78  THR B CB  1 ? 
ATOM   1897 O OG1 . THR B 1 78  ? 29.798 -41.535 31.655 1.000 56.307  0 78  THR B OG1 1 ? 
ATOM   1898 C CG2 . THR B 1 78  ? 29.646 -41.975 34.089 1.000 60.481  0 78  THR B CG2 1 ? 
ATOM   1899 N N   . ASN B 1 79  ? 32.168 -39.018 31.196 1.000 60.953  0 79  ASN B N   1 ? 
ATOM   1900 C CA  . ASN B 1 79  ? 33.110 -38.792 30.113 1.000 59.603  0 79  ASN B CA  1 ? 
ATOM   1901 C C   . ASN B 1 79  ? 33.995 -37.591 30.434 1.000 65.484  0 79  ASN B C   1 ? 
ATOM   1902 O O   . ASN B 1 79  ? 33.668 -36.783 31.300 1.000 56.752  0 79  ASN B O   1 ? 
ATOM   1903 C CB  . ASN B 1 79  ? 32.381 -38.701 28.781 1.000 58.196  0 79  ASN B CB  1 ? 
ATOM   1904 C CG  . ASN B 1 79  ? 31.930 -40.073 28.328 1.000 60.825  0 79  ASN B CG  1 ? 
ATOM   1905 O OD1 . ASN B 1 79  ? 32.739 -41.011 28.201 1.000 59.759  0 79  ASN B OD1 1 ? 
ATOM   1906 N ND2 . ASN B 1 79  ? 30.633 -40.207 28.093 1.000 59.836  0 79  ASN B ND2 1 ? 
ATOM   1907 N N   . ASP B 1 80  ? 35.132 -37.488 29.738 1.000 60.335  0 80  ASP B N   1 ? 
ATOM   1908 C CA  . ASP B 1 80  ? 36.174 -36.557 30.138 1.000 62.217  0 80  ASP B CA  1 ? 
ATOM   1909 C C   . ASP B 1 80  ? 35.756 -35.122 29.835 1.000 57.686  0 80  ASP B C   1 ? 
ATOM   1910 O O   . ASP B 1 80  ? 36.057 -34.208 30.589 1.000 62.087  0 80  ASP B O   1 ? 
ATOM   1911 C CB  . ASP B 1 80  ? 37.500 -36.895 29.471 1.000 61.261  0 80  ASP B CB  1 ? 
ATOM   1912 C CG  . ASP B 1 80  ? 38.011 -38.289 29.805 1.000 70.630  0 80  ASP B CG  1 ? 
ATOM   1913 O OD1 . ASP B 1 80  ? 38.331 -38.501 30.995 1.000 75.393  0 80  ASP B OD1 1 ? 
ATOM   1914 O OD2 . ASP B 1 80  ? 38.045 -39.151 28.893 1.000 69.264  0 80  ASP B OD2 1 ? 
ATOM   1915 N N   . ILE B 1 81  ? 35.095 -34.917 28.701 1.000 53.389  0 81  ILE B N   1 ? 
ATOM   1916 C CA  . ILE B 1 81  ? 35.003 -33.587 28.143 1.000 58.919  0 81  ILE B CA  1 ? 
ATOM   1917 C C   . ILE B 1 81  ? 33.593 -33.367 27.615 1.000 59.470  0 81  ILE B C   1 ? 
ATOM   1918 O O   . ILE B 1 81  ? 32.933 -34.283 27.116 1.000 64.008  0 81  ILE B O   1 ? 
ATOM   1919 C CB  . ILE B 1 81  ? 36.113 -33.391 27.086 1.000 71.284  0 81  ILE B CB  1 ? 
ATOM   1920 C CG1 . ILE B 1 81  ? 37.438 -33.118 27.785 1.000 73.333  0 81  ILE B CG1 1 ? 
ATOM   1921 C CG2 . ILE B 1 81  ? 35.784 -32.299 26.067 1.000 57.842  0 81  ILE B CG2 1 ? 
ATOM   1922 C CD1 . ILE B 1 81  ? 38.656 -33.176 26.889 1.000 79.201  0 81  ILE B CD1 1 ? 
ATOM   1923 N N   . MET B 1 82  ? 33.136 -32.127 27.797 1.000 56.974  0 82  MET B N   1 ? 
ATOM   1924 C CA  . MET B 1 82  ? 31.812 -31.716 27.383 1.000 56.866  0 82  MET B CA  1 ? 
ATOM   1925 C C   . MET B 1 82  ? 31.954 -30.902 26.110 1.000 61.531  0 82  MET B C   1 ? 
ATOM   1926 O O   . MET B 1 82  ? 32.604 -29.855 26.140 1.000 60.285  0 82  MET B O   1 ? 
ATOM   1927 C CB  . MET B 1 82  ? 31.174 -30.784 28.419 1.000 55.867  0 82  MET B CB  1 ? 
ATOM   1928 C CG  . MET B 1 82  ? 29.854 -30.178 27.966 1.000 52.283  0 82  MET B CG  1 ? 
ATOM   1929 S SD  . MET B 1 82  ? 28.595 -31.466 27.843 1.000 57.961  0 82  MET B SD  1 ? 
ATOM   1930 C CE  . MET B 1 82  ? 27.440 -30.516 26.846 1.000 48.855  0 82  MET B CE  1 ? 
ATOM   1931 N N   . LEU B 1 83  ? 31.296 -31.382 25.051 1.000 55.829  0 83  LEU B N   1 ? 
ATOM   1932 C CA  . LEU B 1 83  ? 31.298 -30.713 23.771 1.000 63.513  0 83  LEU B CA  1 ? 
ATOM   1933 C C   . LEU B 1 83  ? 29.908 -30.142 23.547 1.000 53.146  0 83  LEU B C   1 ? 
ATOM   1934 O O   . LEU B 1 83  ? 28.920 -30.847 23.738 1.000 58.132  0 83  LEU B O   1 ? 
ATOM   1935 C CB  . LEU B 1 83  ? 31.656 -31.711 22.664 1.000 69.200  0 83  LEU B CB  1 ? 
ATOM   1936 C CG  . LEU B 1 83  ? 31.829 -31.097 21.267 1.000 73.115  0 83  LEU B CG  1 ? 
ATOM   1937 C CD1 . LEU B 1 83  ? 33.081 -30.242 21.272 1.000 81.937  0 83  LEU B CD1 1 ? 
ATOM   1938 C CD2 . LEU B 1 83  ? 31.892 -32.103 20.139 1.000 76.900  0 83  LEU B CD2 1 ? 
ATOM   1939 N N   . GLY B 1 84  ? 29.867 -28.888 23.103 1.000 47.023  0 84  GLY B N   1 ? 
ATOM   1940 C CA  . GLY B 1 84  ? 28.628 -28.235 22.718 1.000 52.077  0 84  GLY B CA  1 ? 
ATOM   1941 C C   . GLY B 1 84  ? 28.718 -27.662 21.305 1.000 58.791  0 84  GLY B C   1 ? 
ATOM   1942 O O   . GLY B 1 84  ? 29.265 -26.590 21.083 1.000 58.529  0 84  GLY B O   1 ? 
ATOM   1943 N N   . VAL B 1 85  ? 28.157 -28.392 20.335 1.000 60.713  0 85  VAL B N   1 ? 
ATOM   1944 C CA  . VAL B 1 85  ? 27.985 -27.853 18.995 1.000 59.916  0 85  VAL B CA  1 ? 
ATOM   1945 C C   . VAL B 1 85  ? 26.907 -26.778 19.068 1.000 57.002  0 85  VAL B C   1 ? 
ATOM   1946 O O   . VAL B 1 85  ? 25.790 -27.075 19.455 1.000 62.396  0 85  VAL B O   1 ? 
ATOM   1947 C CB  . VAL B 1 85  ? 27.600 -28.994 18.036 1.000 67.350  0 85  VAL B CB  1 ? 
ATOM   1948 C CG1 . VAL B 1 85  ? 27.347 -28.514 16.607 1.000 71.500  0 85  VAL B CG1 1 ? 
ATOM   1949 C CG2 . VAL B 1 85  ? 28.633 -30.118 18.073 1.000 63.456  0 85  VAL B CG2 1 ? 
ATOM   1950 N N   . TYR B 1 86  ? 27.242 -25.540 18.697 1.000 61.432  0 86  TYR B N   1 ? 
ATOM   1951 C CA  . TYR B 1 86  ? 26.451 -24.367 19.041 1.000 56.867  0 86  TYR B CA  1 ? 
ATOM   1952 C C   . TYR B 1 86  ? 26.162 -23.488 17.819 1.000 59.671  0 86  TYR B C   1 ? 
ATOM   1953 O O   . TYR B 1 86  ? 27.091 -22.989 17.182 1.000 69.321  0 86  TYR B O   1 ? 
ATOM   1954 C CB  . TYR B 1 86  ? 27.294 -23.615 20.083 1.000 56.232  0 86  TYR B CB  1 ? 
ATOM   1955 C CG  . TYR B 1 86  ? 26.531 -22.593 20.921 1.000 60.489  0 86  TYR B CG  1 ? 
ATOM   1956 C CD1 . TYR B 1 86  ? 26.275 -21.298 20.476 1.000 65.599  0 86  TYR B CD1 1 ? 
ATOM   1957 C CD2 . TYR B 1 86  ? 26.070 -22.934 22.186 1.000 67.820  0 86  TYR B CD2 1 ? 
ATOM   1958 C CE1 . TYR B 1 86  ? 25.553 -20.392 21.246 1.000 62.828  0 86  TYR B CE1 1 ? 
ATOM   1959 C CE2 . TYR B 1 86  ? 25.363 -22.041 22.966 1.000 58.640  0 86  TYR B CE2 1 ? 
ATOM   1960 C CZ  . TYR B 1 86  ? 25.097 -20.768 22.501 1.000 61.134  0 86  TYR B CZ  1 ? 
ATOM   1961 O OH  . TYR B 1 86  ? 24.415 -19.925 23.333 1.000 62.605  0 86  TYR B OH  1 ? 
ATOM   1962 N N   . ILE B 1 87  ? 24.875 -23.260 17.531 1.000 56.305  0 87  ILE B N   1 ? 
ATOM   1963 C CA  . ILE B 1 87  ? 24.437 -22.370 16.468 1.000 64.061  0 87  ILE B CA  1 ? 
ATOM   1964 C C   . ILE B 1 87  ? 23.944 -21.064 17.096 1.000 62.023  0 87  ILE B C   1 ? 
ATOM   1965 O O   . ILE B 1 87  ? 22.887 -21.040 17.718 1.000 67.629  0 87  ILE B O   1 ? 
ATOM   1966 C CB  . ILE B 1 87  ? 23.358 -23.027 15.577 1.000 66.903  0 87  ILE B CB  1 ? 
ATOM   1967 C CG1 . ILE B 1 87  ? 23.927 -24.171 14.745 1.000 82.756  0 87  ILE B CG1 1 ? 
ATOM   1968 C CG2 . ILE B 1 87  ? 22.717 -21.987 14.659 1.000 72.861  0 87  ILE B CG2 1 ? 
ATOM   1969 C CD1 . ILE B 1 87  ? 24.446 -25.336 15.556 1.000 86.644  0 87  ILE B CD1 1 ? 
ATOM   1970 N N   . PRO B 1 88  ? 24.687 -19.946 16.942 1.000 63.551  0 88  PRO B N   1 ? 
ATOM   1971 C CA  . PRO B 1 88  ? 24.323 -18.657 17.548 1.000 64.470  0 88  PRO B CA  1 ? 
ATOM   1972 C C   . PRO B 1 88  ? 22.912 -18.119 17.331 1.000 71.185  0 88  PRO B C   1 ? 
ATOM   1973 O O   . PRO B 1 88  ? 22.403 -17.385 18.179 1.000 87.026  0 88  PRO B O   1 ? 
ATOM   1974 C CB  . PRO B 1 88  ? 25.366 -17.693 16.955 1.000 61.528  0 88  PRO B CB  1 ? 
ATOM   1975 C CG  . PRO B 1 88  ? 26.579 -18.589 16.730 1.000 63.121  0 88  PRO B CG  1 ? 
ATOM   1976 C CD  . PRO B 1 88  ? 25.977 -19.896 16.236 1.000 67.142  0 88  PRO B CD  1 ? 
ATOM   1977 N N   . ASP B 1 89  ? 22.302 -18.444 16.189 1.000 69.512  0 89  ASP B N   1 ? 
ATOM   1978 C CA  . ASP B 1 89  ? 20.960 -17.968 15.879 1.000 78.386  0 89  ASP B CA  1 ? 
ATOM   1979 C C   . ASP B 1 89  ? 19.900 -18.988 16.280 1.000 70.798  0 89  ASP B C   1 ? 
ATOM   1980 O O   . ASP B 1 89  ? 18.718 -18.698 16.186 1.000 75.626  0 89  ASP B O   1 ? 
ATOM   1981 C CB  . ASP B 1 89  ? 20.704 -17.820 14.385 1.000 91.409  0 89  ASP B CB  1 ? 
ATOM   1982 C CG  . ASP B 1 89  ? 21.648 -16.932 13.596 1.000 79.210  0 89  ASP B CG  1 ? 
ATOM   1983 O OD1 . ASP B 1 89  ? 21.570 -15.704 13.760 1.000 74.164  0 89  ASP B OD1 1 ? 
ATOM   1984 O OD2 . ASP B 1 89  ? 22.466 -17.492 12.848 1.000 91.887  0 89  ASP B OD2 1 ? 
ATOM   1985 N N   . GLU B 1 90  ? 20.322 -20.199 16.655 1.000 69.933  0 90  GLU B N   1 ? 
ATOM   1986 C CA  . GLU B 1 90  ? 19.412 -21.274 17.011 1.000 74.333  0 90  GLU B CA  1 ? 
ATOM   1987 C C   . GLU B 1 90  ? 19.883 -21.910 18.326 1.000 72.722  0 90  GLU B C   1 ? 
ATOM   1988 O O   . GLU B 1 90  ? 20.113 -23.121 18.434 1.000 64.963  0 90  GLU B O   1 ? 
ATOM   1989 C CB  . GLU B 1 90  ? 19.333 -22.258 15.836 1.000 85.231  0 90  GLU B CB  1 ? 
ATOM   1990 C CG  . GLU B 1 90  ? 18.778 -21.667 14.535 1.000 83.781  0 90  GLU B CG  1 ? 
ATOM   1991 C CD  . GLU B 1 90  ? 18.650 -22.645 13.372 1.000 86.433  0 90  GLU B CD  1 ? 
ATOM   1992 O OE1 . GLU B 1 90  ? 18.067 -22.232 12.342 1.000 85.523  0 90  GLU B OE1 1 ? 
ATOM   1993 O OE2 . GLU B 1 90  ? 19.133 -23.807 13.472 1.000 66.339  0 90  GLU B OE2 1 ? 
ATOM   1994 N N   . GLU B 1 91  ? 20.024 -21.068 19.344 1.000 65.212  0 91  GLU B N   1 ? 
ATOM   1995 C CA  . GLU B 1 91  ? 20.524 -21.512 20.639 1.000 69.629  0 91  GLU B CA  1 ? 
ATOM   1996 C C   . GLU B 1 91  ? 19.529 -22.473 21.299 1.000 66.141  0 91  GLU B C   1 ? 
ATOM   1997 O O   . GLU B 1 91  ? 18.328 -22.326 21.115 1.000 64.491  0 91  GLU B O   1 ? 
ATOM   1998 C CB  . GLU B 1 91  ? 20.779 -20.231 21.425 1.000 68.322  0 91  GLU B CB  1 ? 
ATOM   1999 C CG  . GLU B 1 91  ? 21.943 -19.434 20.844 1.000 67.138  0 91  GLU B CG  1 ? 
ATOM   2000 C CD  . GLU B 1 91  ? 22.244 -18.147 21.588 1.000 60.644  0 91  GLU B CD  1 ? 
ATOM   2001 O OE1 . GLU B 1 91  ? 21.352 -17.284 21.519 1.000 63.348  0 91  GLU B OE1 1 ? 
ATOM   2002 O OE2 . GLU B 1 91  ? 23.330 -17.988 22.196 1.000 56.399  0 91  GLU B OE2 1 ? 
ATOM   2003 N N   . ASP B 1 92  ? 20.029 -23.466 22.044 1.000 57.471  0 92  ASP B N   1 ? 
ATOM   2004 C CA  . ASP B 1 92  ? 19.196 -24.534 22.575 1.000 59.815  0 92  ASP B CA  1 ? 
ATOM   2005 C C   . ASP B 1 92  ? 19.211 -24.572 24.109 1.000 59.617  0 92  ASP B C   1 ? 
ATOM   2006 O O   . ASP B 1 92  ? 20.269 -24.724 24.724 1.000 60.598  0 92  ASP B O   1 ? 
ATOM   2007 C CB  . ASP B 1 92  ? 19.623 -25.870 22.004 1.000 54.606  0 92  ASP B CB  1 ? 
ATOM   2008 C CG  . ASP B 1 92  ? 18.699 -27.025 22.362 1.000 60.173  0 92  ASP B CG  1 ? 
ATOM   2009 O OD1 . ASP B 1 92  ? 17.682 -27.211 21.658 1.000 81.404  0 92  ASP B OD1 1 ? 
ATOM   2010 O OD2 . ASP B 1 92  ? 19.014 -27.748 23.332 1.000 68.438  0 92  ASP B OD2 1 ? 
ATOM   2011 N N   . VAL B 1 93  ? 18.013 -24.496 24.714 1.000 54.174  0 93  VAL B N   1 ? 
ATOM   2012 C CA  . VAL B 1 93  ? 17.865 -24.485 26.162 1.000 50.505  0 93  VAL B CA  1 ? 
ATOM   2013 C C   . VAL B 1 93  ? 18.409 -25.782 26.783 1.000 51.668  0 93  VAL B C   1 ? 
ATOM   2014 O O   . VAL B 1 93  ? 18.969 -25.752 27.874 1.000 59.087  0 93  VAL B O   1 ? 
ATOM   2015 C CB  . VAL B 1 93  ? 16.417 -24.249 26.620 1.000 47.688  0 93  VAL B CB  1 ? 
ATOM   2016 C CG1 . VAL B 1 93  ? 15.485 -25.388 26.221 1.000 50.210  0 93  VAL B CG1 1 ? 
ATOM   2017 C CG2 . VAL B 1 93  ? 16.341 -24.026 28.121 1.000 52.079  0 93  VAL B CG2 1 ? 
ATOM   2018 N N   . GLY B 1 94  ? 18.215 -26.918 26.114 1.000 49.199  0 94  GLY B N   1 ? 
ATOM   2019 C CA  . GLY B 1 94  ? 18.674 -28.210 26.607 1.000 56.559  0 94  GLY B CA  1 ? 
ATOM   2020 C C   . GLY B 1 94  ? 20.199 -28.281 26.695 1.000 62.586  0 94  GLY B C   1 ? 
ATOM   2021 O O   . GLY B 1 94  ? 20.749 -28.733 27.702 1.000 57.449  0 94  GLY B O   1 ? 
ATOM   2022 N N   . LEU B 1 95  ? 20.866 -27.776 25.649 1.000 57.688  0 95  LEU B N   1 ? 
ATOM   2023 C CA  . LEU B 1 95  ? 22.317 -27.695 25.623 1.000 58.972  0 95  LEU B CA  1 ? 
ATOM   2024 C C   . LEU B 1 95  ? 22.789 -26.786 26.752 1.000 51.957  0 95  LEU B C   1 ? 
ATOM   2025 O O   . LEU B 1 95  ? 23.739 -27.113 27.465 1.000 49.661  0 95  LEU B O   1 ? 
ATOM   2026 C CB  . LEU B 1 95  ? 22.825 -27.193 24.266 1.000 55.402  0 95  LEU B CB  1 ? 
ATOM   2027 C CG  . LEU B 1 95  ? 24.352 -27.154 24.104 1.000 60.065  0 95  LEU B CG  1 ? 
ATOM   2028 C CD1 . LEU B 1 95  ? 24.962 -28.499 24.479 1.000 56.977  0 95  LEU B CD1 1 ? 
ATOM   2029 C CD2 . LEU B 1 95  ? 24.807 -26.746 22.704 1.000 64.250  0 95  LEU B CD2 1 ? 
ATOM   2030 N N   . GLY B 1 96  ? 22.161 -25.609 26.861 1.000 44.047  0 96  GLY B N   1 ? 
ATOM   2031 C CA  . GLY B 1 96  ? 22.470 -24.697 27.941 1.000 50.673  0 96  GLY B CA  1 ? 
ATOM   2032 C C   . GLY B 1 96  ? 22.483 -25.432 29.288 1.000 49.774  0 96  GLY B C   1 ? 
ATOM   2033 O O   . GLY B 1 96  ? 23.451 -25.335 30.025 1.000 46.054  0 96  GLY B O   1 ? 
ATOM   2034 N N   . MET B 1 97  ? 21.416 -26.188 29.580 1.000 49.682  0 97  MET B N   1 ? 
ATOM   2035 C CA  . MET B 1 97  ? 21.305 -26.924 30.826 1.000 50.215  0 97  MET B CA  1 ? 
ATOM   2036 C C   . MET B 1 97  ? 22.491 -27.874 30.962 1.000 52.032  0 97  MET B C   1 ? 
ATOM   2037 O O   . MET B 1 97  ? 23.142 -27.912 32.013 1.000 55.010  0 97  MET B O   1 ? 
ATOM   2038 C CB  . MET B 1 97  ? 19.949 -27.637 30.895 1.000 49.980  0 97  MET B CB  1 ? 
ATOM   2039 C CG  . MET B 1 97  ? 19.721 -28.397 32.200 1.000 52.834  0 97  MET B CG  1 ? 
ATOM   2040 S SD  . MET B 1 97  ? 20.484 -30.020 32.124 1.000 57.795  0 97  MET B SD  1 ? 
ATOM   2041 C CE  . MET B 1 97  ? 20.798 -30.541 33.819 1.000 53.306  0 97  MET B CE  1 ? 
ATOM   2042 N N   . GLU B 1 98  ? 22.788 -28.607 29.885 1.000 54.942  0 98  GLU B N   1 ? 
ATOM   2043 C CA  . GLU B 1 98  ? 23.853 -29.608 29.886 1.000 50.249  0 98  GLU B CA  1 ? 
ATOM   2044 C C   . GLU B 1 98  ? 25.205 -28.950 30.147 1.000 50.252  0 98  GLU B C   1 ? 
ATOM   2045 O O   . GLU B 1 98  ? 26.056 -29.510 30.858 1.000 53.379  0 98  GLU B O   1 ? 
ATOM   2046 C CB  . GLU B 1 98  ? 23.890 -30.370 28.557 1.000 53.161  0 98  GLU B CB  1 ? 
ATOM   2047 C CG  . GLU B 1 98  ? 22.691 -31.302 28.380 1.000 61.606  0 98  GLU B CG  1 ? 
ATOM   2048 C CD  . GLU B 1 98  ? 22.265 -31.609 26.954 1.000 61.898  0 98  GLU B CD  1 ? 
ATOM   2049 O OE1 . GLU B 1 98  ? 22.928 -31.083 26.020 1.000 54.717  0 98  GLU B OE1 1 ? 
ATOM   2050 O OE2 . GLU B 1 98  ? 21.278 -32.398 26.791 1.000 58.216  0 98  GLU B OE2 1 ? 
ATOM   2051 N N   . LEU B 1 99  ? 25.412 -27.770 29.543 1.000 52.264  0 99  LEU B N   1 ? 
ATOM   2052 C CA  . LEU B 1 99  ? 26.616 -26.994 29.791 1.000 49.271  0 99  LEU B CA  1 ? 
ATOM   2053 C C   . LEU B 1 99  ? 26.761 -26.705 31.286 1.000 52.649  0 99  LEU B C   1 ? 
ATOM   2054 O O   . LEU B 1 99  ? 27.826 -26.923 31.855 1.000 52.396  0 99  LEU B O   1 ? 
ATOM   2055 C CB  . LEU B 1 99  ? 26.583 -25.710 28.964 1.000 51.469  0 99  LEU B CB  1 ? 
ATOM   2056 C CG  . LEU B 1 99  ? 26.670 -25.895 27.442 1.000 59.955  0 99  LEU B CG  1 ? 
ATOM   2057 C CD1 . LEU B 1 99  ? 26.548 -24.566 26.751 1.000 53.401  0 99  LEU B CD1 1 ? 
ATOM   2058 C CD2 . LEU B 1 99  ? 27.977 -26.566 27.042 1.000 62.376  0 99  LEU B CD2 1 ? 
ATOM   2059 N N   . GLY B 1 100 ? 25.671 -26.234 31.912 1.000 52.927  0 100 GLY B N   1 ? 
ATOM   2060 C CA  . GLY B 1 100 ? 25.640 -25.929 33.337 1.000 53.139  0 100 GLY B CA  1 ? 
ATOM   2061 C C   . GLY B 1 100 ? 25.950 -27.167 34.179 1.000 52.351  0 100 GLY B C   1 ? 
ATOM   2062 O O   . GLY B 1 100 ? 26.716 -27.094 35.120 1.000 56.001  0 100 GLY B O   1 ? 
ATOM   2063 N N   . TYR B 1 101 ? 25.433 -28.328 33.780 1.000 51.566  0 101 TYR B N   1 ? 
ATOM   2064 C CA  . TYR B 1 101 ? 25.709 -29.558 34.493 1.000 47.577  0 101 TYR B CA  1 ? 
ATOM   2065 C C   . TYR B 1 101 ? 27.175 -29.953 34.332 1.000 53.426  0 101 TYR B C   1 ? 
ATOM   2066 O O   . TYR B 1 101 ? 27.833 -30.305 35.318 1.000 55.611  0 101 TYR B O   1 ? 
ATOM   2067 C CB  . TYR B 1 101 ? 24.691 -30.614 34.046 1.000 50.251  0 101 TYR B CB  1 ? 
ATOM   2068 C CG  . TYR B 1 101 ? 24.878 -31.934 34.777 1.000 53.304  0 101 TYR B CG  1 ? 
ATOM   2069 C CD1 . TYR B 1 101 ? 24.402 -32.127 36.066 1.000 55.086  0 101 TYR B CD1 1 ? 
ATOM   2070 C CD2 . TYR B 1 101 ? 25.593 -32.968 34.184 1.000 61.715  0 101 TYR B CD2 1 ? 
ATOM   2071 C CE1 . TYR B 1 101 ? 24.603 -33.326 36.739 1.000 57.876  0 101 TYR B CE1 1 ? 
ATOM   2072 C CE2 . TYR B 1 101 ? 25.780 -34.177 34.833 1.000 63.343  0 101 TYR B CE2 1 ? 
ATOM   2073 C CZ  . TYR B 1 101 ? 25.274 -34.360 36.107 1.000 64.839  0 101 TYR B CZ  1 ? 
ATOM   2074 O OH  . TYR B 1 101 ? 25.516 -35.560 36.702 1.000 58.181  0 101 TYR B OH  1 ? 
ATOM   2075 N N   . ALA B 1 102 ? 27.691 -29.859 33.105 1.000 54.114  0 102 ALA B N   1 ? 
ATOM   2076 C CA  . ALA B 1 102 ? 29.096 -30.144 32.840 1.000 60.110  0 102 ALA B CA  1 ? 
ATOM   2077 C C   . ALA B 1 102 ? 30.023 -29.294 33.720 1.000 49.919  0 102 ALA B C   1 ? 
ATOM   2078 O O   . ALA B 1 102 ? 30.984 -29.813 34.286 1.000 56.396  0 102 ALA B O   1 ? 
ATOM   2079 C CB  . ALA B 1 102 ? 29.403 -29.937 31.374 1.000 57.979  0 102 ALA B CB  1 ? 
ATOM   2080 N N   . LEU B 1 103 ? 29.743 -27.996 33.847 1.000 54.825  0 103 LEU B N   1 ? 
ATOM   2081 C CA  . LEU B 1 103 ? 30.488 -27.144 34.768 1.000 55.408  0 103 LEU B CA  1 ? 
ATOM   2082 C C   . LEU B 1 103 ? 30.423 -27.700 36.189 1.000 54.693  0 103 LEU B C   1 ? 
ATOM   2083 O O   . LEU B 1 103 ? 31.434 -27.856 36.856 1.000 56.656  0 103 LEU B O   1 ? 
ATOM   2084 C CB  . LEU B 1 103 ? 29.951 -25.725 34.780 1.000 54.005  0 103 LEU B CB  1 ? 
ATOM   2085 C CG  . LEU B 1 103 ? 30.602 -24.755 35.776 1.000 65.152  0 103 LEU B CG  1 ? 
ATOM   2086 C CD1 . LEU B 1 103 ? 32.024 -24.352 35.406 1.000 56.671  0 103 LEU B CD1 1 ? 
ATOM   2087 C CD2 . LEU B 1 103 ? 29.725 -23.519 35.960 1.000 63.566  0 103 LEU B CD2 1 ? 
ATOM   2088 N N   . SER B 1 104 ? 29.222 -28.036 36.642 1.000 58.929  0 104 SER B N   1 ? 
ATOM   2089 C CA  . SER B 1 104 ? 29.049 -28.545 37.987 1.000 49.354  0 104 SER B CA  1 ? 
ATOM   2090 C C   . SER B 1 104 ? 29.856 -29.822 38.206 1.000 60.781  0 104 SER B C   1 ? 
ATOM   2091 O O   . SER B 1 104 ? 30.207 -30.131 39.342 1.000 58.194  0 104 SER B O   1 ? 
ATOM   2092 C CB  . SER B 1 104 ? 27.572 -28.786 38.271 1.000 50.135  0 104 SER B CB  1 ? 
ATOM   2093 O OG  . SER B 1 104 ? 27.124 -30.110 37.945 1.000 54.090  0 104 SER B OG  1 ? 
ATOM   2094 N N   . GLN B 1 105 ? 30.091 -30.607 37.140 1.000 63.587  0 105 GLN B N   1 ? 
ATOM   2095 C CA  . GLN B 1 105 ? 30.800 -31.871 37.290 1.000 60.601  0 105 GLN B CA  1 ? 
ATOM   2096 C C   . GLN B 1 105 ? 32.288 -31.733 37.006 1.000 53.456  0 105 GLN B C   1 ? 
ATOM   2097 O O   . GLN B 1 105 ? 32.975 -32.735 36.940 1.000 59.338  0 105 GLN B O   1 ? 
ATOM   2098 C CB  . GLN B 1 105 ? 30.265 -32.942 36.347 1.000 59.615  0 105 GLN B CB  1 ? 
ATOM   2099 C CG  . GLN B 1 105 ? 28.836 -33.348 36.662 1.000 52.895  0 105 GLN B CG  1 ? 
ATOM   2100 C CD  . GLN B 1 105 ? 28.723 -34.018 38.009 1.000 56.713  0 105 GLN B CD  1 ? 
ATOM   2101 O OE1 . GLN B 1 105 ? 29.511 -34.895 38.393 1.000 54.105  0 105 GLN B OE1 1 ? 
ATOM   2102 N NE2 . GLN B 1 105 ? 27.763 -33.553 38.780 1.000 59.772  0 105 GLN B NE2 1 ? 
ATOM   2103 N N   . GLY B 1 106 ? 32.803 -30.519 36.839 1.000 55.589  0 106 GLY B N   1 ? 
ATOM   2104 C CA  . GLY B 1 106 ? 34.249 -30.364 36.769 1.000 60.382  0 106 GLY B CA  1 ? 
ATOM   2105 C C   . GLY B 1 106 ? 34.831 -30.671 35.385 1.000 66.909  0 106 GLY B C   1 ? 
ATOM   2106 O O   . GLY B 1 106 ? 36.025 -30.925 35.269 1.000 63.318  0 106 GLY B O   1 ? 
ATOM   2107 N N   . LYS B 1 107 ? 34.009 -30.599 34.331 1.000 59.573  0 107 LYS B N   1 ? 
ATOM   2108 C CA  . LYS B 1 107 ? 34.456 -30.957 32.991 1.000 61.718  0 107 LYS B CA  1 ? 
ATOM   2109 C C   . LYS B 1 107 ? 34.927 -29.732 32.216 1.000 59.862  0 107 LYS B C   1 ? 
ATOM   2110 O O   . LYS B 1 107 ? 34.331 -28.659 32.312 1.000 53.412  0 107 LYS B O   1 ? 
ATOM   2111 C CB  . LYS B 1 107 ? 33.300 -31.505 32.151 1.000 61.227  0 107 LYS B CB  1 ? 
ATOM   2112 C CG  . LYS B 1 107 ? 32.558 -32.674 32.765 1.000 56.945  0 107 LYS B CG  1 ? 
ATOM   2113 C CD  . LYS B 1 107 ? 33.474 -33.841 33.088 1.000 58.569  0 107 LYS B CD  1 ? 
ATOM   2114 C CE  . LYS B 1 107 ? 32.680 -34.918 33.713 1.000 61.923  0 107 LYS B CE  1 ? 
ATOM   2115 N NZ  . LYS B 1 107 ? 33.561 -36.062 33.956 1.000 59.630  0 107 LYS B NZ  1 ? 
ATOM   2116 N N   . TYR B 1 108 ? 35.937 -29.933 31.363 1.000 58.717  0 108 TYR B N   1 ? 
ATOM   2117 C CA  . TYR B 1 108 ? 36.262 -28.956 30.332 1.000 60.422  0 108 TYR B CA  1 ? 
ATOM   2118 C C   . TYR B 1 108 ? 35.064 -28.797 29.396 1.000 53.815  0 108 TYR B C   1 ? 
ATOM   2119 O O   . TYR B 1 108 ? 34.479 -29.771 28.932 1.000 54.773  0 108 TYR B O   1 ? 
ATOM   2120 C CB  . TYR B 1 108 ? 37.494 -29.374 29.529 1.000 63.132  0 108 TYR B CB  1 ? 
ATOM   2121 C CG  . TYR B 1 108 ? 38.006 -28.340 28.535 1.000 56.323  0 108 TYR B CG  1 ? 
ATOM   2122 C CD1 . TYR B 1 108 ? 38.637 -27.184 28.983 1.000 56.566  0 108 TYR B CD1 1 ? 
ATOM   2123 C CD2 . TYR B 1 108 ? 37.927 -28.549 27.158 1.000 57.028  0 108 TYR B CD2 1 ? 
ATOM   2124 C CE1 . TYR B 1 108 ? 39.136 -26.227 28.108 1.000 58.189  0 108 TYR B CE1 1 ? 
ATOM   2125 C CE2 . TYR B 1 108 ? 38.455 -27.615 26.272 1.000 60.343  0 108 TYR B CE2 1 ? 
ATOM   2126 C CZ  . TYR B 1 108 ? 39.061 -26.460 26.748 1.000 56.405  0 108 TYR B CZ  1 ? 
ATOM   2127 O OH  . TYR B 1 108 ? 39.571 -25.528 25.919 1.000 60.473  0 108 TYR B OH  1 ? 
ATOM   2128 N N   . VAL B 1 109 ? 34.663 -27.549 29.174 1.000 55.119  0 109 VAL B N   1 ? 
ATOM   2129 C CA  . VAL B 1 109 ? 33.489 -27.260 28.381 1.000 55.368  0 109 VAL B CA  1 ? 
ATOM   2130 C C   . VAL B 1 109 ? 33.950 -26.554 27.114 1.000 54.184  0 109 VAL B C   1 ? 
ATOM   2131 O O   . VAL B 1 109 ? 34.408 -25.417 27.201 1.000 54.138  0 109 VAL B O   1 ? 
ATOM   2132 C CB  . VAL B 1 109 ? 32.482 -26.376 29.156 1.000 55.679  0 109 VAL B CB  1 ? 
ATOM   2133 C CG1 . VAL B 1 109 ? 31.305 -25.998 28.272 1.000 49.610  0 109 VAL B CG1 1 ? 
ATOM   2134 C CG2 . VAL B 1 109 ? 32.006 -27.012 30.466 1.000 54.893  0 109 VAL B CG2 1 ? 
ATOM   2135 N N   . LEU B 1 110 ? 33.782 -27.226 25.965 1.000 57.375  0 110 LEU B N   1 ? 
ATOM   2136 C CA  . LEU B 1 110 ? 34.220 -26.705 24.676 1.000 57.707  0 110 LEU B CA  1 ? 
ATOM   2137 C C   . LEU B 1 110 ? 32.994 -26.494 23.795 1.000 54.079  0 110 LEU B C   1 ? 
ATOM   2138 O O   . LEU B 1 110 ? 32.279 -27.453 23.520 1.000 57.124  0 110 LEU B O   1 ? 
ATOM   2139 C CB  . LEU B 1 110 ? 35.128 -27.777 24.071 1.000 64.492  0 110 LEU B CB  1 ? 
ATOM   2140 C CG  . LEU B 1 110 ? 36.219 -27.352 23.074 1.000 68.120  0 110 LEU B CG  1 ? 
ATOM   2141 C CD1 . LEU B 1 110 ? 36.168 -28.300 21.906 1.000 67.470  0 110 LEU B CD1 1 ? 
ATOM   2142 C CD2 . LEU B 1 110 ? 36.229 -25.929 22.576 1.000 68.843  0 110 LEU B CD2 1 ? 
ATOM   2143 N N   . LEU B 1 111 ? 32.766 -25.259 23.354 1.000 55.584  0 111 LEU B N   1 ? 
ATOM   2144 C CA  . LEU B 1 111 ? 31.805 -24.987 22.299 1.000 61.646  0 111 LEU B CA  1 ? 
ATOM   2145 C C   . LEU B 1 111 ? 32.511 -24.976 20.944 1.000 67.205  0 111 LEU B C   1 ? 
ATOM   2146 O O   . LEU B 1 111 ? 33.631 -24.482 20.810 1.000 58.171  0 111 LEU B O   1 ? 
ATOM   2147 C CB  . LEU B 1 111 ? 31.077 -23.658 22.486 1.000 64.775  0 111 LEU B CB  1 ? 
ATOM   2148 C CG  . LEU B 1 111 ? 30.419 -23.406 23.842 1.000 64.810  0 111 LEU B CG  1 ? 
ATOM   2149 C CD1 . LEU B 1 111 ? 29.798 -22.021 23.868 1.000 56.367  0 111 LEU B CD1 1 ? 
ATOM   2150 C CD2 . LEU B 1 111 ? 29.405 -24.483 24.116 1.000 68.263  0 111 LEU B CD2 1 ? 
ATOM   2151 N N   . VAL B 1 112 ? 31.773 -25.464 19.935 1.000 74.643  0 112 VAL B N   1 ? 
ATOM   2152 C CA  . VAL B 1 112 ? 32.197 -25.492 18.545 1.000 65.972  0 112 VAL B CA  1 ? 
ATOM   2153 C C   . VAL B 1 112 ? 31.108 -24.846 17.695 1.000 59.690  0 112 VAL B C   1 ? 
ATOM   2154 O O   . VAL B 1 112 ? 29.996 -25.359 17.644 1.000 55.687  0 112 VAL B O   1 ? 
ATOM   2155 C CB  . VAL B 1 112 ? 32.447 -26.929 18.053 1.000 73.905  0 112 VAL B CB  1 ? 
ATOM   2156 C CG1 . VAL B 1 112 ? 33.084 -26.942 16.668 1.000 74.387  0 112 VAL B CG1 1 ? 
ATOM   2157 C CG2 . VAL B 1 112 ? 33.310 -27.706 19.024 1.000 81.523  0 112 VAL B CG2 1 ? 
ATOM   2158 N N   . ILE B 1 113 ? 31.462 -23.763 16.994 1.000 67.188  0 113 ILE B N   1 ? 
ATOM   2159 C CA  . ILE B 1 113 ? 30.557 -22.991 16.160 1.000 70.365  0 113 ILE B CA  1 ? 
ATOM   2160 C C   . ILE B 1 113 ? 30.979 -23.148 14.694 1.000 72.030  0 113 ILE B C   1 ? 
ATOM   2161 O O   . ILE B 1 113 ? 32.155 -23.018 14.358 1.000 77.162  0 113 ILE B O   1 ? 
ATOM   2162 C CB  . ILE B 1 113 ? 30.594 -21.523 16.612 1.000 65.136  0 113 ILE B CB  1 ? 
ATOM   2163 C CG1 . ILE B 1 113 ? 30.125 -21.405 18.062 1.000 70.107  0 113 ILE B CG1 1 ? 
ATOM   2164 C CG2 . ILE B 1 113 ? 29.819 -20.595 15.662 1.000 65.549  0 113 ILE B CG2 1 ? 
ATOM   2165 C CD1 . ILE B 1 113 ? 30.246 -20.013 18.655 1.000 65.380  0 113 ILE B CD1 1 ? 
ATOM   2166 N N   . PRO B 1 114 ? 30.038 -23.407 13.765 1.000 70.572  0 114 PRO B N   1 ? 
ATOM   2167 C CA  . PRO B 1 114 ? 30.360 -23.426 12.333 1.000 72.364  0 114 PRO B CA  1 ? 
ATOM   2168 C C   . PRO B 1 114 ? 31.114 -22.164 11.915 1.000 70.559  0 114 PRO B C   1 ? 
ATOM   2169 O O   . PRO B 1 114 ? 30.823 -21.081 12.406 1.000 66.911  0 114 PRO B O   1 ? 
ATOM   2170 C CB  . PRO B 1 114 ? 28.990 -23.536 11.664 1.000 71.638  0 114 PRO B CB  1 ? 
ATOM   2171 C CG  . PRO B 1 114 ? 28.139 -24.251 12.710 1.000 82.149  0 114 PRO B CG  1 ? 
ATOM   2172 C CD  . PRO B 1 114 ? 28.624 -23.692 14.046 1.000 68.941  0 114 PRO B CD  1 ? 
ATOM   2173 N N   . ASP B 1 115 ? 32.105 -22.328 11.031 1.000 71.240  0 115 ASP B N   1 ? 
ATOM   2174 C CA  . ASP B 1 115 ? 32.989 -21.237 10.644 1.000 75.243  0 115 ASP B CA  1 ? 
ATOM   2175 C C   . ASP B 1 115 ? 32.174 -20.086 10.069 1.000 62.492  0 115 ASP B C   1 ? 
ATOM   2176 O O   . ASP B 1 115 ? 32.489 -18.923 10.317 1.000 58.089  0 115 ASP B O   1 ? 
ATOM   2177 C CB  . ASP B 1 115 ? 34.053 -21.679 9.647  1.000 72.019  0 115 ASP B CB  1 ? 
ATOM   2178 C CG  . ASP B 1 115 ? 35.058 -22.703 10.156 1.000 72.823  0 115 ASP B CG  1 ? 
ATOM   2179 O OD1 . ASP B 1 115 ? 34.617 -23.809 10.570 1.000 70.987  0 115 ASP B OD1 1 ? 
ATOM   2180 O OD2 . ASP B 1 115 ? 36.279 -22.388 10.129 1.000 76.344  0 115 ASP B OD2 1 ? 
ATOM   2181 N N   . GLU B 1 116 ? 31.110 -20.417 9.324  1.000 61.080  0 116 GLU B N   1 ? 
ATOM   2182 C CA  . GLU B 1 116 ? 30.254 -19.403 8.711  1.000 74.911  0 116 GLU B CA  1 ? 
ATOM   2183 C C   . GLU B 1 116 ? 29.533 -18.547 9.762  1.000 78.832  0 116 GLU B C   1 ? 
ATOM   2184 O O   . GLU B 1 116 ? 29.030 -17.481 9.427  1.000 80.580  0 116 GLU B O   1 ? 
ATOM   2185 C CB  . GLU B 1 116 ? 29.227 -19.993 7.727  1.000 75.458  0 116 GLU B CB  1 ? 
ATOM   2186 C CG  . GLU B 1 116 ? 28.412 -21.181 8.248  1.000 78.433  0 116 GLU B CG  1 ? 
ATOM   2187 C CD  . GLU B 1 116 ? 29.042 -22.563 8.055  1.000 89.120  0 116 GLU B CD  1 ? 
ATOM   2188 O OE1 . GLU B 1 116 ? 30.271 -22.767 8.319  1.000 76.321  0 116 GLU B OE1 1 ? 
ATOM   2189 O OE2 . GLU B 1 116 ? 28.260 -23.467 7.661  1.000 84.299  0 116 GLU B OE2 1 ? 
ATOM   2190 N N   . ASP B 1 117 ? 29.431 -19.024 11.015 1.000 84.601  0 117 ASP B N   1 ? 
ATOM   2191 C CA  . ASP B 1 117 ? 28.712 -18.318 12.066 1.000 73.263  0 117 ASP B CA  1 ? 
ATOM   2192 C C   . ASP B 1 117 ? 29.657 -17.797 13.144 1.000 73.188  0 117 ASP B C   1 ? 
ATOM   2193 O O   . ASP B 1 117 ? 29.222 -16.999 13.972 1.000 72.304  0 117 ASP B O   1 ? 
ATOM   2194 C CB  . ASP B 1 117 ? 27.641 -19.185 12.714 1.000 73.769  0 117 ASP B CB  1 ? 
ATOM   2195 C CG  . ASP B 1 117 ? 26.557 -19.715 11.788 1.000 68.154  0 117 ASP B CG  1 ? 
ATOM   2196 O OD1 . ASP B 1 117 ? 26.096 -18.935 10.934 1.000 74.227  0 117 ASP B OD1 1 ? 
ATOM   2197 O OD2 . ASP B 1 117 ? 26.169 -20.895 11.948 1.000 70.913  0 117 ASP B OD2 1 ? 
ATOM   2198 N N   . TYR B 1 118 ? 30.932 -18.224 13.142 1.000 65.224  0 118 TYR B N   1 ? 
ATOM   2199 C CA  . TYR B 1 118 ? 31.847 -17.819 14.199 1.000 73.579  0 118 TYR B CA  1 ? 
ATOM   2200 C C   . TYR B 1 118 ? 32.014 -16.298 14.192 1.000 65.090  0 118 TYR B C   1 ? 
ATOM   2201 O O   . TYR B 1 118 ? 32.300 -15.718 13.167 1.000 67.655  0 118 TYR B O   1 ? 
ATOM   2202 C CB  . TYR B 1 118 ? 33.203 -18.517 14.088 1.000 74.789  0 118 TYR B CB  1 ? 
ATOM   2203 C CG  . TYR B 1 118 ? 34.074 -18.358 15.331 1.000 76.825  0 118 TYR B CG  1 ? 
ATOM   2204 C CD1 . TYR B 1 118 ? 34.775 -17.176 15.585 1.000 72.590  0 118 TYR B CD1 1 ? 
ATOM   2205 C CD2 . TYR B 1 118 ? 34.187 -19.398 16.260 1.000 81.083  0 118 TYR B CD2 1 ? 
ATOM   2206 C CE1 . TYR B 1 118 ? 35.559 -17.038 16.719 1.000 68.598  0 118 TYR B CE1 1 ? 
ATOM   2207 C CE2 . TYR B 1 118 ? 34.965 -19.270 17.400 1.000 71.467  0 118 TYR B CE2 1 ? 
ATOM   2208 C CZ  . TYR B 1 118 ? 35.652 -18.088 17.621 1.000 66.781  0 118 TYR B CZ  1 ? 
ATOM   2209 O OH  . TYR B 1 118 ? 36.397 -18.003 18.759 1.000 64.644  0 118 TYR B OH  1 ? 
ATOM   2210 N N   . GLY B 1 119 ? 31.844 -15.663 15.352 1.000 67.043  0 119 GLY B N   1 ? 
ATOM   2211 C CA  . GLY B 1 119 ? 31.826 -14.209 15.491 1.000 62.276  0 119 GLY B CA  1 ? 
ATOM   2212 C C   . GLY B 1 119 ? 30.424 -13.655 15.810 1.000 62.489  0 119 GLY B C   1 ? 
ATOM   2213 O O   . GLY B 1 119 ? 30.283 -12.552 16.347 1.000 64.219  0 119 GLY B O   1 ? 
ATOM   2214 N N   . LYS B 1 120 ? 29.370 -14.395 15.442 1.000 61.502  0 120 LYS B N   1 ? 
ATOM   2215 C CA  . LYS B 1 120 ? 28.007 -13.935 15.680 1.000 73.083  0 120 LYS B CA  1 ? 
ATOM   2216 C C   . LYS B 1 120 ? 27.683 -13.959 17.178 1.000 67.452  0 120 LYS B C   1 ? 
ATOM   2217 O O   . LYS B 1 120 ? 28.262 -14.740 17.933 1.000 63.329  0 120 LYS B O   1 ? 
ATOM   2218 C CB  . LYS B 1 120 ? 27.001 -14.753 14.862 1.000 77.427  0 120 LYS B CB  1 ? 
ATOM   2219 C CG  . LYS B 1 120 ? 27.049 -14.474 13.366 1.000 84.667  0 120 LYS B CG  1 ? 
ATOM   2220 C CD  . LYS B 1 120 ? 25.705 -14.611 12.661 1.000 90.524  0 120 LYS B CD  1 ? 
ATOM   2221 C CE  . LYS B 1 120 ? 25.375 -16.018 12.304 1.000 89.776  0 120 LYS B CE  1 ? 
ATOM   2222 N NZ  . LYS B 1 120 ? 25.709 -16.305 10.913 1.000 77.939  0 120 LYS B NZ  1 ? 
ATOM   2223 N N   . PRO B 1 121 ? 26.741 -13.112 17.640 1.000 70.382  0 121 PRO B N   1 ? 
ATOM   2224 C CA  . PRO B 1 121 ? 26.523 -12.928 19.078 1.000 73.595  0 121 PRO B CA  1 ? 
ATOM   2225 C C   . PRO B 1 121 ? 26.024 -14.204 19.755 1.000 72.409  0 121 PRO B C   1 ? 
ATOM   2226 O O   . PRO B 1 121 ? 25.216 -14.912 19.162 1.000 61.124  0 121 PRO B O   1 ? 
ATOM   2227 C CB  . PRO B 1 121 ? 25.504 -11.765 19.163 1.000 74.459  0 121 PRO B CB  1 ? 
ATOM   2228 C CG  . PRO B 1 121 ? 25.487 -11.141 17.763 1.000 75.182  0 121 PRO B CG  1 ? 
ATOM   2229 C CD  . PRO B 1 121 ? 25.842 -12.278 16.812 1.000 70.457  0 121 PRO B CD  1 ? 
ATOM   2230 N N   . ILE B 1 122 ? 26.550 -14.506 20.957 1.000 69.532  0 122 ILE B N   1 ? 
ATOM   2231 C CA  . ILE B 1 122 ? 26.072 -15.636 21.744 1.000 65.191  0 122 ILE B CA  1 ? 
ATOM   2232 C C   . ILE B 1 122 ? 25.662 -15.155 23.136 1.000 60.612  0 122 ILE B C   1 ? 
ATOM   2233 O O   . ILE B 1 122 ? 26.184 -14.166 23.677 1.000 59.029  0 122 ILE B O   1 ? 
ATOM   2234 C CB  . ILE B 1 122 ? 27.104 -16.777 21.849 1.000 58.856  0 122 ILE B CB  1 ? 
ATOM   2235 C CG1 . ILE B 1 122 ? 28.293 -16.400 22.705 1.000 54.630  0 122 ILE B CG1 1 ? 
ATOM   2236 C CG2 . ILE B 1 122 ? 27.532 -17.281 20.470 1.000 68.431  0 122 ILE B CG2 1 ? 
ATOM   2237 C CD1 . ILE B 1 122 ? 29.292 -17.530 22.880 1.000 57.720  0 122 ILE B CD1 1 ? 
ATOM   2238 N N   . ASN B 1 123 ? 24.746 -15.920 23.735 1.000 57.848  0 123 ASN B N   1 ? 
ATOM   2239 C CA  . ASN B 1 123 ? 24.302 -15.646 25.090 1.000 62.126  0 123 ASN B CA  1 ? 
ATOM   2240 C C   . ASN B 1 123 ? 25.488 -15.554 26.056 1.000 52.680  0 123 ASN B C   1 ? 
ATOM   2241 O O   . ASN B 1 123 ? 26.377 -16.386 26.040 1.000 56.971  0 123 ASN B O   1 ? 
ATOM   2242 C CB  . ASN B 1 123 ? 23.333 -16.708 25.574 1.000 62.217  0 123 ASN B CB  1 ? 
ATOM   2243 C CG  . ASN B 1 123 ? 22.606 -16.236 26.806 1.000 60.572  0 123 ASN B CG  1 ? 
ATOM   2244 O OD1 . ASN B 1 123 ? 23.198 -16.187 27.896 1.000 52.854  0 123 ASN B OD1 1 ? 
ATOM   2245 N ND2 . ASN B 1 123 ? 21.345 -15.839 26.640 1.000 58.663  0 123 ASN B ND2 1 ? 
ATOM   2246 N N   . LEU B 1 124 ? 25.466 -14.524 26.898 1.000 56.591  0 124 LEU B N   1 ? 
ATOM   2247 C CA  . LEU B 1 124 ? 26.444 -14.285 27.946 1.000 57.897  0 124 LEU B CA  1 ? 
ATOM   2248 C C   . LEU B 1 124 ? 26.715 -15.536 28.771 1.000 56.420  0 124 LEU B C   1 ? 
ATOM   2249 O O   . LEU B 1 124 ? 27.846 -15.763 29.165 1.000 60.011  0 124 LEU B O   1 ? 
ATOM   2250 C CB  . LEU B 1 124 ? 25.961 -13.162 28.863 1.000 55.555  0 124 LEU B CB  1 ? 
ATOM   2251 C CG  . LEU B 1 124 ? 26.855 -12.902 30.079 1.000 59.464  0 124 LEU B CG  1 ? 
ATOM   2252 C CD1 . LEU B 1 124 ? 28.206 -12.406 29.665 1.000 56.147  0 124 LEU B CD1 1 ? 
ATOM   2253 C CD2 . LEU B 1 124 ? 26.201 -11.923 31.009 1.000 59.495  0 124 LEU B CD2 1 ? 
ATOM   2254 N N   . MET B 1 125 ? 25.676 -16.302 29.104 1.000 51.646  0 125 MET B N   1 ? 
ATOM   2255 C CA  . MET B 1 125 ? 25.869 -17.423 30.002 1.000 51.741  0 125 MET B CA  1 ? 
ATOM   2256 C C   . MET B 1 125 ? 26.577 -18.539 29.256 1.000 52.463  0 125 MET B C   1 ? 
ATOM   2257 O O   . MET B 1 125 ? 27.292 -19.307 29.879 1.000 50.984  0 125 MET B O   1 ? 
ATOM   2258 C CB  . MET B 1 125 ? 24.563 -17.920 30.629 1.000 52.017  0 125 MET B CB  1 ? 
ATOM   2259 C CG  . MET B 1 125 ? 23.706 -16.818 31.228 1.000 48.973  0 125 MET B CG  1 ? 
ATOM   2260 S SD  . MET B 1 125 ? 24.604 -15.610 32.221 1.000 51.589  0 125 MET B SD  1 ? 
ATOM   2261 C CE  . MET B 1 125 ? 24.765 -16.562 33.744 1.000 52.739  0 125 MET B CE  1 ? 
ATOM   2262 N N   . SER B 1 126 ? 26.400 -18.609 27.930 1.000 52.626  0 126 SER B N   1 ? 
ATOM   2263 C CA  . SER B 1 126 ? 27.133 -19.574 27.129 1.000 53.277  0 126 SER B CA  1 ? 
ATOM   2264 C C   . SER B 1 126 ? 28.617 -19.204 27.058 1.000 55.385  0 126 SER B C   1 ? 
ATOM   2265 O O   . SER B 1 126 ? 29.499 -20.043 27.220 1.000 52.853  0 126 SER B O   1 ? 
ATOM   2266 C CB  . SER B 1 126 ? 26.539 -19.669 25.775 1.000 61.298  0 126 SER B CB  1 ? 
ATOM   2267 O OG  . SER B 1 126 ? 25.250 -20.242 25.850 1.000 49.135  0 126 SER B OG  1 ? 
ATOM   2268 N N   . TRP B 1 127 ? 28.873 -17.927 26.803 1.000 52.954  0 127 TRP B N   1 ? 
ATOM   2269 C CA  . TRP B 1 127 ? 30.210 -17.370 26.802 1.000 55.895  0 127 TRP B CA  1 ? 
ATOM   2270 C C   . TRP B 1 127 ? 30.927 -17.713 28.109 1.000 59.577  0 127 TRP B C   1 ? 
ATOM   2271 O O   . TRP B 1 127 ? 32.104 -18.073 28.107 1.000 62.096  0 127 TRP B O   1 ? 
ATOM   2272 C CB  . TRP B 1 127 ? 30.083 -15.849 26.574 1.000 61.729  0 127 TRP B CB  1 ? 
ATOM   2273 C CG  . TRP B 1 127 ? 31.353 -15.061 26.753 1.000 62.925  0 127 TRP B CG  1 ? 
ATOM   2274 C CD1 . TRP B 1 127 ? 32.268 -14.788 25.778 1.000 66.329  0 127 TRP B CD1 1 ? 
ATOM   2275 C CD2 . TRP B 1 127 ? 31.883 -14.489 27.966 1.000 62.828  0 127 TRP B CD2 1 ? 
ATOM   2276 N NE1 . TRP B 1 127 ? 33.311 -14.074 26.292 1.000 68.063  0 127 TRP B NE1 1 ? 
ATOM   2277 C CE2 . TRP B 1 127 ? 33.109 -13.884 27.631 1.000 64.681  0 127 TRP B CE2 1 ? 
ATOM   2278 C CE3 . TRP B 1 127 ? 31.456 -14.426 29.292 1.000 61.967  0 127 TRP B CE3 1 ? 
ATOM   2279 C CZ2 . TRP B 1 127 ? 33.895 -13.225 28.572 1.000 58.755  0 127 TRP B CZ2 1 ? 
ATOM   2280 C CZ3 . TRP B 1 127 ? 32.250 -13.804 30.228 1.000 62.191  0 127 TRP B CZ3 1 ? 
ATOM   2281 C CH2 . TRP B 1 127 ? 33.458 -13.211 29.872 1.000 58.682  0 127 TRP B CH2 1 ? 
ATOM   2282 N N   . GLY B 1 128 ? 30.202 -17.598 29.228 1.000 60.470  0 128 GLY B N   1 ? 
ATOM   2283 C CA  . GLY B 1 128 ? 30.772 -17.770 30.556 1.000 53.791  0 128 GLY B CA  1 ? 
ATOM   2284 C C   . GLY B 1 128 ? 30.938 -19.235 30.972 1.000 51.125  0 128 GLY B C   1 ? 
ATOM   2285 O O   . GLY B 1 128 ? 31.931 -19.576 31.591 1.000 51.855  0 128 GLY B O   1 ? 
ATOM   2286 N N   . VAL B 1 129 ? 29.975 -20.120 30.685 1.000 59.170  0 129 VAL B N   1 ? 
ATOM   2287 C CA  . VAL B 1 129 ? 30.143 -21.519 31.083 1.000 62.783  0 129 VAL B CA  1 ? 
ATOM   2288 C C   . VAL B 1 129 ? 31.318 -22.119 30.327 1.000 55.294  0 129 VAL B C   1 ? 
ATOM   2289 O O   . VAL B 1 129 ? 31.827 -23.130 30.780 1.000 52.327  0 129 VAL B O   1 ? 
ATOM   2290 C CB  . VAL B 1 129 ? 29.048 -22.571 30.830 1.000 51.954  0 129 VAL B CB  1 ? 
ATOM   2291 C CG1 . VAL B 1 129 ? 28.215 -22.863 32.045 1.000 63.274  0 129 VAL B CG1 1 ? 
ATOM   2292 C CG2 . VAL B 1 129 ? 28.288 -22.305 29.544 1.000 50.883  0 129 VAL B CG2 1 ? 
ATOM   2293 N N   . SER B 1 130 ? 31.557 -21.629 29.102 1.000 51.290  0 130 SER B N   1 ? 
ATOM   2294 C CA  . SER B 1 130 ? 32.587 -22.181 28.241 1.000 60.511  0 130 SER B CA  1 ? 
ATOM   2295 C C   . SER B 1 130 ? 33.946 -21.959 28.879 1.000 48.685  0 130 SER B C   1 ? 
ATOM   2296 O O   . SER B 1 130 ? 34.181 -20.898 29.456 1.000 55.860  0 130 SER B O   1 ? 
ATOM   2297 C CB  . SER B 1 130 ? 32.546 -21.539 26.903 1.000 56.894  0 130 SER B CB  1 ? 
ATOM   2298 O OG  . SER B 1 130 ? 31.275 -21.797 26.350 1.000 71.643  0 130 SER B OG  1 ? 
ATOM   2299 N N   . ASP B 1 131 ? 34.815 -22.962 28.734 1.000 54.960  0 131 ASP B N   1 ? 
ATOM   2300 C CA  . ASP B 1 131 ? 36.241 -22.760 28.931 1.000 56.583  0 131 ASP B CA  1 ? 
ATOM   2301 C C   . ASP B 1 131 ? 36.941 -22.341 27.635 1.000 61.086  0 131 ASP B C   1 ? 
ATOM   2302 O O   . ASP B 1 131 ? 38.016 -21.750 27.686 1.000 59.131  0 131 ASP B O   1 ? 
ATOM   2303 C CB  . ASP B 1 131 ? 36.857 -24.001 29.519 1.000 57.928  0 131 ASP B CB  1 ? 
ATOM   2304 C CG  . ASP B 1 131 ? 36.358 -24.332 30.911 1.000 56.012  0 131 ASP B CG  1 ? 
ATOM   2305 O OD1 . ASP B 1 131 ? 36.509 -23.445 31.775 1.000 63.397  0 131 ASP B OD1 1 ? 
ATOM   2306 O OD2 . ASP B 1 131 ? 35.833 -25.475 31.089 1.000 57.827  0 131 ASP B OD2 1 ? 
ATOM   2307 N N   . ASN B 1 132 ? 36.306 -22.584 26.484 1.000 57.050  0 132 ASN B N   1 ? 
ATOM   2308 C CA  . ASN B 1 132 ? 36.864 -22.168 25.212 1.000 62.785  0 132 ASN B CA  1 ? 
ATOM   2309 C C   . ASN B 1 132 ? 35.782 -22.287 24.144 1.000 63.085  0 132 ASN B C   1 ? 
ATOM   2310 O O   . ASN B 1 132 ? 34.877 -23.124 24.269 1.000 63.855  0 132 ASN B O   1 ? 
ATOM   2311 C CB  . ASN B 1 132 ? 38.075 -23.046 24.895 1.000 66.830  0 132 ASN B CB  1 ? 
ATOM   2312 C CG  . ASN B 1 132 ? 38.928 -22.578 23.736 1.000 66.796  0 132 ASN B CG  1 ? 
ATOM   2313 O OD1 . ASN B 1 132 ? 39.870 -23.283 23.367 1.000 77.938  0 132 ASN B OD1 1 ? 
ATOM   2314 N ND2 . ASN B 1 132 ? 38.685 -21.404 23.169 1.000 64.228  0 132 ASN B ND2 1 ? 
ATOM   2315 N N   . VAL B 1 133 ? 35.880 -21.461 23.096 1.000 64.475  0 133 VAL B N   1 ? 
ATOM   2316 C CA  . VAL B 1 133 ? 35.031 -21.666 21.932 1.000 64.480  0 133 VAL B CA  1 ? 
ATOM   2317 C C   . VAL B 1 133 ? 35.806 -21.478 20.624 1.000 65.892  0 133 VAL B C   1 ? 
ATOM   2318 O O   . VAL B 1 133 ? 36.472 -20.476 20.396 1.000 67.205  0 133 VAL B O   1 ? 
ATOM   2319 C CB  . VAL B 1 133 ? 33.702 -20.878 22.009 1.000 74.321  0 133 VAL B CB  1 ? 
ATOM   2320 C CG1 . VAL B 1 133 ? 33.666 -19.851 23.128 1.000 66.754  0 133 VAL B CG1 1 ? 
ATOM   2321 C CG2 . VAL B 1 133 ? 33.222 -20.319 20.671 1.000 72.460  0 133 VAL B CG2 1 ? 
ATOM   2322 N N   . ILE B 1 134 ? 35.661 -22.496 19.769 1.000 67.201  0 134 ILE B N   1 ? 
ATOM   2323 C CA  . ILE B 1 134 ? 36.466 -22.695 18.578 1.000 64.906  0 134 ILE B CA  1 ? 
ATOM   2324 C C   . ILE B 1 134 ? 35.533 -22.837 17.380 1.000 73.154  0 134 ILE B C   1 ? 
ATOM   2325 O O   . ILE B 1 134 ? 34.320 -22.995 17.537 1.000 63.379  0 134 ILE B O   1 ? 
ATOM   2326 C CB  . ILE B 1 134 ? 37.352 -23.946 18.726 1.000 55.739  0 134 ILE B CB  1 ? 
ATOM   2327 C CG1 . ILE B 1 134 ? 36.520 -25.218 18.813 1.000 58.548  0 134 ILE B CG1 1 ? 
ATOM   2328 C CG2 . ILE B 1 134 ? 38.278 -23.803 19.929 1.000 63.118  0 134 ILE B CG2 1 ? 
ATOM   2329 C CD1 . ILE B 1 134 ? 37.303 -26.509 18.658 1.000 60.632  0 134 ILE B CD1 1 ? 
ATOM   2330 N N   . LYS B 1 135 ? 36.134 -22.825 16.185 1.000 67.290  0 135 LYS B N   1 ? 
ATOM   2331 C CA  . LYS B 1 135 ? 35.363 -22.937 14.963 1.000 70.645  0 135 LYS B CA  1 ? 
ATOM   2332 C C   . LYS B 1 135 ? 35.364 -24.406 14.565 1.000 67.380  0 135 LYS B C   1 ? 
ATOM   2333 O O   . LYS B 1 135 ? 36.240 -25.164 14.986 1.000 63.231  0 135 LYS B O   1 ? 
ATOM   2334 C CB  . LYS B 1 135 ? 35.816 -21.930 13.902 1.000 83.088  0 135 LYS B CB  1 ? 
ATOM   2335 C CG  . LYS B 1 135 ? 37.288 -21.682 13.746 1.000 96.697  0 135 LYS B CG  1 ? 
ATOM   2336 C CD  . LYS B 1 135 ? 37.584 -20.485 12.846 1.000 108.016 0 135 LYS B CD  1 ? 
ATOM   2337 C CE  . LYS B 1 135 ? 37.191 -19.192 13.497 1.000 103.927 0 135 LYS B CE  1 ? 
ATOM   2338 N NZ  . LYS B 1 135 ? 37.934 -18.057 12.945 1.000 98.244  0 135 LYS B NZ  1 ? 
ATOM   2339 N N   . MET B 1 136 ? 34.337 -24.811 13.809 1.000 60.666  0 136 MET B N   1 ? 
ATOM   2340 C CA  . MET B 1 136 ? 34.211 -26.195 13.385 1.000 67.362  0 136 MET B CA  1 ? 
ATOM   2341 C C   . MET B 1 136 ? 35.509 -26.702 12.748 1.000 69.292  0 136 MET B C   1 ? 
ATOM   2342 O O   . MET B 1 136 ? 35.886 -27.848 12.972 1.000 69.356  0 136 MET B O   1 ? 
ATOM   2343 C CB  . MET B 1 136 ? 33.046 -26.348 12.415 1.000 67.786  0 136 MET B CB  1 ? 
ATOM   2344 C CG  . MET B 1 136 ? 32.749 -27.787 12.048 1.000 73.713  0 136 MET B CG  1 ? 
ATOM   2345 S SD  . MET B 1 136 ? 32.007 -28.758 13.375 1.000 69.747  0 136 MET B SD  1 ? 
ATOM   2346 C CE  . MET B 1 136 ? 30.511 -27.771 13.471 1.000 63.641  0 136 MET B CE  1 ? 
ATOM   2347 N N   . SER B 1 137 ? 36.215 -25.836 12.005 1.000 71.022  0 137 SER B N   1 ? 
ATOM   2348 C CA  . SER B 1 137 ? 37.384 -26.252 11.242 1.000 75.878  0 137 SER B CA  1 ? 
ATOM   2349 C C   . SER B 1 137 ? 38.585 -26.522 12.146 1.000 76.078  0 137 SER B C   1 ? 
ATOM   2350 O O   . SER B 1 137 ? 39.590 -27.022 11.654 1.000 76.465  0 137 SER B O   1 ? 
ATOM   2351 C CB  . SER B 1 137 ? 37.746 -25.225 10.169 1.000 69.785  0 137 SER B CB  1 ? 
ATOM   2352 O OG  . SER B 1 137 ? 38.240 -24.013 10.747 1.000 68.399  0 137 SER B OG  1 ? 
ATOM   2353 N N   . GLN B 1 138 ? 38.520 -26.143 13.438 1.000 75.668  0 138 GLN B N   1 ? 
ATOM   2354 C CA  . GLN B 1 138 ? 39.627 -26.377 14.366 1.000 65.479  0 138 GLN B CA  1 ? 
ATOM   2355 C C   . GLN B 1 138 ? 39.446 -27.673 15.174 1.000 65.853  0 138 GLN B C   1 ? 
ATOM   2356 O O   . GLN B 1 138 ? 40.328 -28.089 15.941 1.000 66.191  0 138 GLN B O   1 ? 
ATOM   2357 C CB  . GLN B 1 138 ? 39.791 -25.220 15.344 1.000 63.746  0 138 GLN B CB  1 ? 
ATOM   2358 C CG  . GLN B 1 138 ? 40.202 -23.900 14.708 1.000 66.945  0 138 GLN B CG  1 ? 
ATOM   2359 C CD  . GLN B 1 138 ? 40.092 -22.738 15.672 1.000 69.974  0 138 GLN B CD  1 ? 
ATOM   2360 O OE1 . GLN B 1 138 ? 39.034 -22.480 16.247 1.000 68.090  0 138 GLN B OE1 1 ? 
ATOM   2361 N NE2 . GLN B 1 138 ? 41.177 -22.018 15.878 1.000 75.134  0 138 GLN B NE2 1 ? 
ATOM   2362 N N   . LEU B 1 139 ? 38.296 -28.332 15.006 1.000 56.711  0 139 LEU B N   1 ? 
ATOM   2363 C CA  . LEU B 1 139 ? 37.921 -29.416 15.895 1.000 64.385  0 139 LEU B CA  1 ? 
ATOM   2364 C C   . LEU B 1 139 ? 38.740 -30.664 15.581 1.000 66.331  0 139 LEU B C   1 ? 
ATOM   2365 O O   . LEU B 1 139 ? 39.109 -31.372 16.517 1.000 71.738  0 139 LEU B O   1 ? 
ATOM   2366 C CB  . LEU B 1 139 ? 36.413 -29.675 15.810 1.000 66.078  0 139 LEU B CB  1 ? 
ATOM   2367 C CG  . LEU B 1 139 ? 35.856 -30.809 16.686 1.000 68.821  0 139 LEU B CG  1 ? 
ATOM   2368 C CD1 . LEU B 1 139 ? 36.265 -30.697 18.153 1.000 67.668  0 139 LEU B CD1 1 ? 
ATOM   2369 C CD2 . LEU B 1 139 ? 34.337 -30.882 16.585 1.000 63.071  0 139 LEU B CD2 1 ? 
ATOM   2370 N N   . LYS B 1 140 ? 39.013 -30.937 14.285 1.000 72.750  0 140 LYS B N   1 ? 
ATOM   2371 C CA  . LYS B 1 140 ? 39.779 -32.111 13.863 1.000 75.956  0 140 LYS B CA  1 ? 
ATOM   2372 C C   . LYS B 1 140 ? 41.135 -32.164 14.568 1.000 65.165  0 140 LYS B C   1 ? 
ATOM   2373 O O   . LYS B 1 140 ? 41.662 -33.253 14.803 1.000 74.759  0 140 LYS B O   1 ? 
ATOM   2374 C CB  . LYS B 1 140 ? 40.084 -32.193 12.355 1.000 79.391  0 140 LYS B CB  1 ? 
ATOM   2375 N N   . ASP B 1 141 ? 41.702 -30.993 14.909 1.000 64.042  0 141 ASP B N   1 ? 
ATOM   2376 C CA  . ASP B 1 141 ? 43.090 -30.953 15.355 1.000 69.200  0 141 ASP B CA  1 ? 
ATOM   2377 C C   . ASP B 1 141 ? 43.201 -30.433 16.782 1.000 79.417  0 141 ASP B C   1 ? 
ATOM   2378 O O   . ASP B 1 141 ? 44.311 -30.211 17.277 1.000 65.805  0 141 ASP B O   1 ? 
ATOM   2379 C CB  . ASP B 1 141 ? 43.975 -30.088 14.460 1.000 79.679  0 141 ASP B CB  1 ? 
ATOM   2380 C CG  . ASP B 1 141 ? 43.932 -30.378 12.965 1.000 85.254  0 141 ASP B CG  1 ? 
ATOM   2381 O OD1 . ASP B 1 141 ? 43.885 -31.565 12.572 1.000 83.026  0 141 ASP B OD1 1 ? 
ATOM   2382 O OD2 . ASP B 1 141 ? 43.953 -29.409 12.200 1.000 88.963  0 141 ASP B OD2 1 ? 
ATOM   2383 N N   . PHE B 1 142 ? 42.058 -30.196 17.434 1.000 82.964  0 142 PHE B N   1 ? 
ATOM   2384 C CA  . PHE B 1 142 ? 42.072 -29.748 18.814 1.000 76.021  0 142 PHE B CA  1 ? 
ATOM   2385 C C   . PHE B 1 142 ? 42.767 -30.810 19.662 1.000 59.791  0 142 PHE B C   1 ? 
ATOM   2386 O O   . PHE B 1 142 ? 42.436 -31.996 19.564 1.000 64.430  0 142 PHE B O   1 ? 
ATOM   2387 C CB  . PHE B 1 142 ? 40.643 -29.483 19.296 1.000 83.281  0 142 PHE B CB  1 ? 
ATOM   2388 C CG  . PHE B 1 142 ? 40.608 -28.771 20.638 1.000 71.868  0 142 PHE B CG  1 ? 
ATOM   2389 C CD1 . PHE B 1 142 ? 40.674 -27.388 20.708 1.000 69.997  0 142 PHE B CD1 1 ? 
ATOM   2390 C CD2 . PHE B 1 142 ? 40.536 -29.491 21.818 1.000 70.905  0 142 PHE B CD2 1 ? 
ATOM   2391 C CE1 . PHE B 1 142 ? 40.658 -26.744 21.926 1.000 74.221  0 142 PHE B CE1 1 ? 
ATOM   2392 C CE2 . PHE B 1 142 ? 40.529 -28.835 23.037 1.000 69.709  0 142 PHE B CE2 1 ? 
ATOM   2393 C CZ  . PHE B 1 142 ? 40.600 -27.473 23.086 1.000 69.908  0 142 PHE B CZ  1 ? 
ATOM   2394 N N   . ASN B 1 143 ? 43.713 -30.377 20.506 1.000 58.367  0 143 ASN B N   1 ? 
ATOM   2395 C CA  . ASN B 1 143 ? 44.399 -31.310 21.382 1.000 64.850  0 143 ASN B CA  1 ? 
ATOM   2396 C C   . ASN B 1 143 ? 43.633 -31.429 22.702 1.000 68.381  0 143 ASN B C   1 ? 
ATOM   2397 O O   . ASN B 1 143 ? 43.808 -30.602 23.584 1.000 64.536  0 143 ASN B O   1 ? 
ATOM   2398 C CB  . ASN B 1 143 ? 45.830 -30.872 21.666 1.000 62.991  0 143 ASN B CB  1 ? 
ATOM   2399 C CG  . ASN B 1 143 ? 46.575 -31.924 22.466 1.000 66.395  0 143 ASN B CG  1 ? 
ATOM   2400 O OD1 . ASN B 1 143 ? 46.011 -32.963 22.838 1.000 60.900  0 143 ASN B OD1 1 ? 
ATOM   2401 N ND2 . ASN B 1 143 ? 47.842 -31.675 22.754 1.000 66.905  0 143 ASN B ND2 1 ? 
ATOM   2402 N N   . PHE B 1 144 ? 42.827 -32.485 22.848 1.000 62.813  0 144 PHE B N   1 ? 
ATOM   2403 C CA  . PHE B 1 144 ? 42.015 -32.675 24.037 1.000 68.515  0 144 PHE B CA  1 ? 
ATOM   2404 C C   . PHE B 1 144 ? 42.838 -33.113 25.250 1.000 74.764  0 144 PHE B C   1 ? 
ATOM   2405 O O   . PHE B 1 144 ? 42.299 -33.188 26.358 1.000 76.422  0 144 PHE B O   1 ? 
ATOM   2406 C CB  . PHE B 1 144 ? 40.886 -33.675 23.762 1.000 62.261  0 144 PHE B CB  1 ? 
ATOM   2407 C CG  . PHE B 1 144 ? 39.801 -33.064 22.898 1.000 72.831  0 144 PHE B CG  1 ? 
ATOM   2408 C CD1 . PHE B 1 144 ? 38.829 -32.232 23.463 1.000 73.444  0 144 PHE B CD1 1 ? 
ATOM   2409 C CD2 . PHE B 1 144 ? 39.766 -33.290 21.525 1.000 77.741  0 144 PHE B CD2 1 ? 
ATOM   2410 C CE1 . PHE B 1 144 ? 37.841 -31.665 22.679 1.000 72.614  0 144 PHE B CE1 1 ? 
ATOM   2411 C CE2 . PHE B 1 144 ? 38.770 -32.719 20.746 1.000 85.528  0 144 PHE B CE2 1 ? 
ATOM   2412 C CZ  . PHE B 1 144 ? 37.807 -31.914 21.323 1.000 75.227  0 144 PHE B CZ  1 ? 
ATOM   2413 N N   . ASN B 1 145 ? 44.135 -33.376 25.074 1.000 73.732  0 145 ASN B N   1 ? 
ATOM   2414 C CA  . ASN B 1 145 ? 44.960 -33.796 26.197 1.000 64.204  0 145 ASN B CA  1 ? 
ATOM   2415 C C   . ASN B 1 145 ? 45.508 -32.577 26.929 1.000 57.321  0 145 ASN B C   1 ? 
ATOM   2416 O O   . ASN B 1 145 ? 45.958 -32.710 28.066 1.000 61.614  0 145 ASN B O   1 ? 
ATOM   2417 C CB  . ASN B 1 145 ? 46.100 -34.718 25.766 1.000 76.581  0 145 ASN B CB  1 ? 
ATOM   2418 C CG  . ASN B 1 145 ? 45.599 -36.071 25.319 1.000 81.551  0 145 ASN B CG  1 ? 
ATOM   2419 O OD1 . ASN B 1 145 ? 44.915 -36.763 26.084 1.000 81.258  0 145 ASN B OD1 1 ? 
ATOM   2420 N ND2 . ASN B 1 145 ? 45.901 -36.462 24.088 1.000 81.743  0 145 ASN B ND2 1 ? 
ATOM   2421 N N   . LYS B 1 146 ? 45.511 -31.414 26.265 1.000 62.079  0 146 LYS B N   1 ? 
ATOM   2422 C CA  . LYS B 1 146 ? 45.997 -30.169 26.856 1.000 72.307  0 146 LYS B CA  1 ? 
ATOM   2423 C C   . LYS B 1 146 ? 44.973 -29.061 26.603 1.000 71.366  0 146 LYS B C   1 ? 
ATOM   2424 O O   . LYS B 1 146 ? 45.287 -28.017 26.023 1.000 74.153  0 146 LYS B O   1 ? 
ATOM   2425 C CB  . LYS B 1 146 ? 47.373 -29.783 26.290 1.000 79.908  0 146 LYS B CB  1 ? 
ATOM   2426 C CG  . LYS B 1 146 ? 48.419 -30.883 26.359 1.000 92.446  0 146 LYS B CG  1 ? 
ATOM   2427 C CD  . LYS B 1 146 ? 49.797 -30.468 25.853 1.000 98.800  0 146 LYS B CD  1 ? 
ATOM   2428 C CE  . LYS B 1 146 ? 50.518 -29.641 26.868 1.000 102.139 0 146 LYS B CE  1 ? 
ATOM   2429 N NZ  . LYS B 1 146 ? 51.841 -29.254 26.383 1.000 95.349  0 146 LYS B NZ  1 ? 
ATOM   2430 N N   . PRO B 1 147 ? 43.715 -29.229 27.076 1.000 71.063  0 147 PRO B N   1 ? 
ATOM   2431 C CA  . PRO B 1 147 ? 42.656 -28.247 26.818 1.000 62.425  0 147 PRO B CA  1 ? 
ATOM   2432 C C   . PRO B 1 147 ? 42.922 -27.015 27.672 1.000 56.906  0 147 PRO B C   1 ? 
ATOM   2433 O O   . PRO B 1 147 ? 43.218 -27.150 28.852 1.000 61.756  0 147 PRO B O   1 ? 
ATOM   2434 C CB  . PRO B 1 147 ? 41.400 -29.000 27.262 1.000 64.292  0 147 PRO B CB  1 ? 
ATOM   2435 C CG  . PRO B 1 147 ? 41.891 -29.905 28.376 1.000 63.153  0 147 PRO B CG  1 ? 
ATOM   2436 C CD  . PRO B 1 147 ? 43.287 -30.320 27.970 1.000 62.293  0 147 PRO B CD  1 ? 
ATOM   2437 N N   . ARG B 1 148 ? 42.833 -25.831 27.079 1.000 58.516  0 148 ARG B N   1 ? 
ATOM   2438 C CA  . ARG B 1 148 ? 43.145 -24.601 27.796 1.000 58.251  0 148 ARG B CA  1 ? 
ATOM   2439 C C   . ARG B 1 148 ? 41.981 -23.621 27.715 1.000 56.733  0 148 ARG B C   1 ? 
ATOM   2440 O O   . ARG B 1 148 ? 41.073 -23.781 26.908 1.000 55.584  0 148 ARG B O   1 ? 
ATOM   2441 C CB  . ARG B 1 148 ? 44.368 -23.884 27.206 1.000 66.460  0 148 ARG B CB  1 ? 
ATOM   2442 C CG  . ARG B 1 148 ? 45.648 -24.711 27.203 1.000 74.872  0 148 ARG B CG  1 ? 
ATOM   2443 C CD  . ARG B 1 148 ? 46.148 -25.040 28.606 1.000 79.235  0 148 ARG B CD  1 ? 
ATOM   2444 N NE  . ARG B 1 148 ? 47.275 -25.981 28.605 1.000 94.268  0 148 ARG B NE  1 ? 
ATOM   2445 C CZ  . ARG B 1 148 ? 47.302 -27.218 29.100 1.000 103.483 0 148 ARG B CZ  1 ? 
ATOM   2446 N NH1 . ARG B 1 148 ? 48.482 -27.783 29.344 1.000 97.509  0 148 ARG B NH1 1 ? 
ATOM   2447 N NH2 . ARG B 1 148 ? 46.172 -27.839 29.423 1.000 102.653 0 148 ARG B NH2 1 ? 
ATOM   2448 N N   . PHE B 1 149 ? 42.062 -22.595 28.558 1.000 56.157  0 149 PHE B N   1 ? 
ATOM   2449 C CA  . PHE B 1 149 ? 41.056 -21.563 28.668 1.000 63.224  0 149 PHE B CA  1 ? 
ATOM   2450 C C   . PHE B 1 149 ? 41.340 -20.493 27.626 1.000 60.879  0 149 PHE B C   1 ? 
ATOM   2451 O O   . PHE B 1 149 ? 42.439 -19.978 27.590 1.000 65.525  0 149 PHE B O   1 ? 
ATOM   2452 C CB  . PHE B 1 149 ? 41.029 -20.871 30.043 1.000 60.046  0 149 PHE B CB  1 ? 
ATOM   2453 C CG  . PHE B 1 149 ? 39.986 -19.764 30.051 1.000 63.867  0 149 PHE B CG  1 ? 
ATOM   2454 C CD1 . PHE B 1 149 ? 38.658 -20.036 30.390 1.000 74.720  0 149 PHE B CD1 1 ? 
ATOM   2455 C CD2 . PHE B 1 149 ? 40.320 -18.467 29.652 1.000 62.291  0 149 PHE B CD2 1 ? 
ATOM   2456 C CE1 . PHE B 1 149 ? 37.699 -19.023 30.365 1.000 68.778  0 149 PHE B CE1 1 ? 
ATOM   2457 C CE2 . PHE B 1 149 ? 39.367 -17.460 29.629 1.000 61.199  0 149 PHE B CE2 1 ? 
ATOM   2458 C CZ  . PHE B 1 149 ? 38.057 -17.744 29.984 1.000 67.559  0 149 PHE B CZ  1 ? 
ATOM   2459 N N   . ASP B 1 150 ? 40.312 -20.089 26.870 1.000 62.772  0 150 ASP B N   1 ? 
ATOM   2460 C CA  . ASP B 1 150 ? 40.393 -18.898 26.050 1.000 63.653  0 150 ASP B CA  1 ? 
ATOM   2461 C C   . ASP B 1 150 ? 38.995 -18.319 25.846 1.000 64.229  0 150 ASP B C   1 ? 
ATOM   2462 O O   . ASP B 1 150 ? 38.000 -18.997 26.032 1.000 57.687  0 150 ASP B O   1 ? 
ATOM   2463 C CB  . ASP B 1 150 ? 41.027 -19.224 24.704 1.000 70.935  0 150 ASP B CB  1 ? 
ATOM   2464 C CG  . ASP B 1 150 ? 41.767 -18.096 24.002 1.000 73.425  0 150 ASP B CG  1 ? 
ATOM   2465 O OD1 . ASP B 1 150 ? 41.667 -16.922 24.453 1.000 72.840  0 150 ASP B OD1 1 ? 
ATOM   2466 O OD2 . ASP B 1 150 ? 42.448 -18.410 23.009 1.000 90.318  0 150 ASP B OD2 1 ? 
ATOM   2467 N N   . PHE B 1 151 ? 38.935 -17.060 25.414 1.000 61.865  0 151 PHE B N   1 ? 
ATOM   2468 C CA  . PHE B 1 151 ? 37.684 -16.373 25.156 1.000 60.394  0 151 PHE B CA  1 ? 
ATOM   2469 C C   . PHE B 1 151 ? 37.252 -16.545 23.703 1.000 60.834  0 151 PHE B C   1 ? 
ATOM   2470 O O   . PHE B 1 151 ? 38.081 -16.515 22.808 1.000 62.589  0 151 PHE B O   1 ? 
ATOM   2471 C CB  . PHE B 1 151 ? 37.877 -14.880 25.385 1.000 54.813  0 151 PHE B CB  1 ? 
ATOM   2472 C CG  . PHE B 1 151 ? 38.177 -14.426 26.806 1.000 62.040  0 151 PHE B CG  1 ? 
ATOM   2473 C CD1 . PHE B 1 151 ? 37.187 -14.426 27.788 1.000 64.409  0 151 PHE B CD1 1 ? 
ATOM   2474 C CD2 . PHE B 1 151 ? 39.427 -13.917 27.143 1.000 61.896  0 151 PHE B CD2 1 ? 
ATOM   2475 C CE1 . PHE B 1 151 ? 37.459 -13.971 29.077 1.000 60.793  0 151 PHE B CE1 1 ? 
ATOM   2476 C CE2 . PHE B 1 151 ? 39.691 -13.468 28.430 1.000 63.933  0 151 PHE B CE2 1 ? 
ATOM   2477 C CZ  . PHE B 1 151 ? 38.703 -13.482 29.391 1.000 61.124  0 151 PHE B CZ  1 ? 
ATOM   2478 N N   . TYR B 1 152 ? 35.941 -16.663 23.473 1.000 63.849  0 152 TYR B N   1 ? 
ATOM   2479 C CA  . TYR B 1 152 ? 35.322 -16.425 22.171 1.000 69.943  0 152 TYR B CA  1 ? 
ATOM   2480 C C   . TYR B 1 152 ? 35.781 -15.090 21.582 1.000 70.843  0 152 TYR B C   1 ? 
ATOM   2481 O O   . TYR B 1 152 ? 35.756 -14.068 22.262 1.000 67.783  0 152 TYR B O   1 ? 
ATOM   2482 C CB  . TYR B 1 152 ? 33.802 -16.363 22.325 1.000 59.796  0 152 TYR B CB  1 ? 
ATOM   2483 C CG  . TYR B 1 152 ? 32.931 -16.324 21.078 1.000 59.587  0 152 TYR B CG  1 ? 
ATOM   2484 C CD1 . TYR B 1 152 ? 33.218 -17.079 19.947 1.000 67.093  0 152 TYR B CD1 1 ? 
ATOM   2485 C CD2 . TYR B 1 152 ? 31.775 -15.556 21.057 1.000 65.268  0 152 TYR B CD2 1 ? 
ATOM   2486 C CE1 . TYR B 1 152 ? 32.380 -17.068 18.839 1.000 58.075  0 152 TYR B CE1 1 ? 
ATOM   2487 C CE2 . TYR B 1 152 ? 30.931 -15.538 19.963 1.000 64.471  0 152 TYR B CE2 1 ? 
ATOM   2488 C CZ  . TYR B 1 152 ? 31.244 -16.272 18.837 1.000 64.445  0 152 TYR B CZ  1 ? 
ATOM   2489 O OH  . TYR B 1 152 ? 30.339 -16.205 17.811 1.000 55.779  0 152 TYR B OH  1 ? 
ATOM   2490 N N   . GLU B 1 153 ? 36.200 -15.126 20.314 1.000 79.996  0 153 GLU B N   1 ? 
ATOM   2491 C CA  . GLU B 1 153 ? 36.545 -13.928 19.560 1.000 78.288  0 153 GLU B CA  1 ? 
ATOM   2492 C C   . GLU B 1 153 ? 35.297 -13.556 18.761 1.000 73.418  0 153 GLU B C   1 ? 
ATOM   2493 O O   . GLU B 1 153 ? 35.187 -13.857 17.571 1.000 83.204  0 153 GLU B O   1 ? 
ATOM   2494 C CB  . GLU B 1 153 ? 37.805 -14.134 18.704 1.000 66.679  0 153 GLU B CB  1 ? 
ATOM   2495 N N   . GLY B 1 154 ? 34.340 -12.934 19.450 1.000 75.609  0 154 GLY B N   1 ? 
ATOM   2496 C CA  . GLY B 1 154 ? 33.010 -12.751 18.906 1.000 65.890  0 154 GLY B CA  1 ? 
ATOM   2497 C C   . GLY B 1 154 ? 32.110 -12.028 19.893 1.000 58.452  0 154 GLY B C   1 ? 
ATOM   2498 O O   . GLY B 1 154 ? 32.551 -11.583 20.944 1.000 75.434  0 154 GLY B O   1 ? 
ATOM   2499 N N   . ALA B 1 155 ? 30.851 -11.858 19.490 1.000 60.798  0 155 ALA B N   1 ? 
ATOM   2500 C CA  . ALA B 1 155 ? 29.915 -11.008 20.203 1.000 72.084  0 155 ALA B CA  1 ? 
ATOM   2501 C C   . ALA B 1 155 ? 29.153 -11.803 21.265 1.000 61.740  0 155 ALA B C   1 ? 
ATOM   2502 O O   . ALA B 1 155 ? 28.897 -12.984 21.075 1.000 61.945  0 155 ALA B O   1 ? 
ATOM   2503 C CB  . ALA B 1 155 ? 28.973 -10.388 19.201 1.000 67.178  0 155 ALA B CB  1 ? 
ATOM   2504 N N   . VAL B 1 156 ? 28.784 -11.138 22.364 1.000 62.139  0 156 VAL B N   1 ? 
ATOM   2505 C CA  . VAL B 1 156 ? 27.902 -11.698 23.385 1.000 74.929  0 156 VAL B CA  1 ? 
ATOM   2506 C C   . VAL B 1 156 ? 26.757 -10.726 23.668 1.000 72.103  0 156 VAL B C   1 ? 
ATOM   2507 O O   . VAL B 1 156 ? 26.984 -9.525  23.720 1.000 71.188  0 156 VAL B O   1 ? 
ATOM   2508 C CB  . VAL B 1 156 ? 28.681 -11.923 24.692 1.000 71.825  0 156 VAL B CB  1 ? 
ATOM   2509 C CG1 . VAL B 1 156 ? 29.899 -12.813 24.480 1.000 69.123  0 156 VAL B CG1 1 ? 
ATOM   2510 C CG2 . VAL B 1 156 ? 29.106 -10.585 25.292 1.000 73.557  0 156 VAL B CG2 1 ? 
ATOM   2511 N N   . TYR B 1 157 ? 25.569 -11.249 23.986 1.000 69.511  0 157 TYR B N   1 ? 
ATOM   2512 C CA  . TYR B 1 157 ? 24.445 -10.426 24.425 1.000 59.473  0 157 TYR B CA  1 ? 
ATOM   2513 C C   . TYR B 1 157 ? 23.966 -10.894 25.823 1.000 63.189  0 157 TYR B C   1 ? 
ATOM   2514 O O   . TYR B 1 157 ? 23.440 -10.029 26.561 1.000 72.236  0 157 TYR B O   1 ? 
ATOM   2515 C CB  . TYR B 1 157 ? 23.358 -10.505 23.346 1.000 55.441  0 157 TYR B CB  1 ? 
ATOM   2516 C CG  . TYR B 1 157 ? 22.677 -11.862 23.289 1.000 51.809  0 157 TYR B CG  1 ? 
ATOM   2517 C CD1 . TYR B 1 157 ? 21.630 -12.177 24.135 1.000 62.268  0 157 TYR B CD1 1 ? 
ATOM   2518 C CD2 . TYR B 1 157 ? 23.067 -12.820 22.371 1.000 52.113  0 157 TYR B CD2 1 ? 
ATOM   2519 C CE1 . TYR B 1 157 ? 20.999 -13.412 24.070 1.000 60.655  0 157 TYR B CE1 1 ? 
ATOM   2520 C CE2 . TYR B 1 157 ? 22.446 -14.055 22.283 1.000 60.094  0 157 TYR B CE2 1 ? 
ATOM   2521 C CZ  . TYR B 1 157 ? 21.417 -14.359 23.153 1.000 61.201  0 157 TYR B CZ  1 ? 
ATOM   2522 O OH  . TYR B 1 157 ? 20.862 -15.604 23.104 1.000 54.980  0 157 TYR B OH  1 ? 
ATOM   2523 O OXT . TYR B 1 157 ? 24.145 -12.096 26.156 1.000 66.383  0 157 TYR B OXT 1 ? 
HETATM 2524 C C2  . 2DR C 2 .   ? 19.739 -14.100 33.030 1.000 53.011  0 201 2DR A C2  1 ? 
HETATM 2525 C C3  . 2DR C 2 .   ? 18.453 -14.531 32.326 1.000 57.692  0 201 2DR A C3  1 ? 
HETATM 2526 C C4  . 2DR C 2 .   ? 18.972 -15.265 31.083 1.000 53.577  0 201 2DR A C4  1 ? 
HETATM 2527 C C5  . 2DR C 2 .   ? 18.880 -14.536 29.766 1.000 56.441  0 201 2DR A C5  1 ? 
HETATM 2528 O O3  . 2DR C 2 .   ? 17.666 -15.374 33.182 1.000 56.465  0 201 2DR A O3  1 ? 
HETATM 2529 O O4  . 2DR C 2 .   ? 20.364 -15.549 31.314 1.000 58.225  0 201 2DR A O4  1 ? 
HETATM 2530 O O5  . 2DR C 2 .   ? 19.236 -15.422 28.713 1.000 58.625  0 201 2DR A O5  1 ? 
HETATM 2531 C C1  . 2DR C 2 .   ? 20.801 -15.090 32.587 1.000 52.949  0 201 2DR A C1  1 ? 
HETATM 2532 C C2  . 2DR D 2 .   ? 21.130 -33.185 24.341 1.000 71.373  0 201 2DR B C2  1 ? 
HETATM 2533 C C3  . 2DR D 2 .   ? 21.269 -32.025 23.338 1.000 66.850  0 201 2DR B C3  1 ? 
HETATM 2534 C C4  . 2DR D 2 .   ? 20.232 -30.999 23.818 1.000 66.640  0 201 2DR B C4  1 ? 
HETATM 2535 C C5  . 2DR D 2 .   ? 18.925 -30.972 23.063 1.000 68.703  0 201 2DR B C5  1 ? 
HETATM 2536 O O3  . 2DR D 2 .   ? 22.601 -31.496 23.367 1.000 62.432  0 201 2DR B O3  1 ? 
HETATM 2537 O O4  . 2DR D 2 .   ? 19.944 -31.320 25.192 1.000 64.627  0 201 2DR B O4  1 ? 
HETATM 2538 O O5  . 2DR D 2 .   ? 18.098 -29.904 23.501 1.000 58.454  0 201 2DR B O5  1 ? 
HETATM 2539 C C1  . 2DR D 2 .   ? 20.455 -32.610 25.583 1.000 75.970  0 201 2DR B C1  1 ? 
HETATM 2540 O O   . HOH E 3 .   ? 33.288 -1.864  30.544 1.000 72.756  0 301 HOH A O   1 ? 
HETATM 2541 O O   . HOH E 3 .   ? 21.202 -3.695  34.989 1.000 58.277  0 302 HOH A O   1 ? 
HETATM 2542 O O   . HOH E 3 .   ? 13.189 -5.873  35.987 1.000 58.958  0 303 HOH A O   1 ? 
HETATM 2543 O O   . HOH E 3 .   ? 18.586 -4.752  51.704 1.000 57.982  0 304 HOH A O   1 ? 
HETATM 2544 O O   . HOH E 3 .   ? 7.019  -13.460 21.406 1.000 61.093  0 305 HOH A O   1 ? 
HETATM 2545 O O   . HOH E 3 .   ? 15.485 -11.996 53.269 1.000 53.787  0 306 HOH A O   1 ? 
HETATM 2546 O O   . HOH E 3 .   ? 5.733  -27.220 46.743 1.000 56.629  0 307 HOH A O   1 ? 
HETATM 2547 O O   . HOH E 3 .   ? 11.895 -23.881 54.663 1.000 54.154  0 308 HOH A O   1 ? 
HETATM 2548 O O   . HOH E 3 .   ? 17.823 -7.482  42.312 1.000 50.714  0 309 HOH A O   1 ? 
HETATM 2549 O O   . HOH E 3 .   ? 5.008  -25.138 48.149 1.000 58.290  0 310 HOH A O   1 ? 
HETATM 2550 O O   . HOH E 3 .   ? 11.823 -16.627 29.449 1.000 53.697  0 311 HOH A O   1 ? 
HETATM 2551 O O   . HOH E 3 .   ? 16.029 -9.753  34.954 1.000 43.860  0 312 HOH A O   1 ? 
HETATM 2552 O O   . HOH E 3 .   ? 11.175 -6.751  30.446 1.000 59.286  0 313 HOH A O   1 ? 
HETATM 2553 O O   . HOH E 3 .   ? 0.159  -15.291 40.456 1.000 54.998  0 314 HOH A O   1 ? 
HETATM 2554 O O   . HOH E 3 .   ? 11.650 -18.871 27.995 1.000 56.849  0 315 HOH A O   1 ? 
HETATM 2555 O O   . HOH E 3 .   ? 25.160 -5.154  41.296 1.000 56.665  0 316 HOH A O   1 ? 
HETATM 2556 O O   . HOH E 3 .   ? 5.618  -35.974 30.828 1.000 55.262  0 317 HOH A O   1 ? 
HETATM 2557 O O   . HOH E 3 .   ? 18.917 -2.432  32.234 1.000 62.941  0 318 HOH A O   1 ? 
HETATM 2558 O O   . HOH E 3 .   ? 8.786  -11.124 19.502 1.000 61.908  0 319 HOH A O   1 ? 
HETATM 2559 O O   . HOH E 3 .   ? 16.393 1.604   32.095 1.000 69.719  0 320 HOH A O   1 ? 
HETATM 2560 O O   . HOH F 3 .   ? 33.134 -43.665 27.922 1.000 67.401  0 301 HOH B O   1 ? 
HETATM 2561 O O   . HOH F 3 .   ? 25.217 -25.793 10.545 1.000 66.290  0 302 HOH B O   1 ? 
HETATM 2562 O O   . HOH F 3 .   ? 33.596 -50.158 24.488 1.000 63.592  0 303 HOH B O   1 ? 
HETATM 2563 O O   . HOH F 3 .   ? 30.071 -47.612 18.479 1.000 69.675  0 304 HOH B O   1 ? 
HETATM 2564 O O   . HOH F 3 .   ? 34.976 -12.777 24.490 1.000 58.879  0 305 HOH B O   1 ? 
HETATM 2565 O O   . HOH F 3 .   ? 23.391 -34.260 20.873 1.000 68.326  0 306 HOH B O   1 ? 
HETATM 2566 O O   . HOH F 3 .   ? 22.700 -23.932 21.730 1.000 57.637  0 307 HOH B O   1 ? 
HETATM 2567 O O   . HOH F 3 .   ? 21.244 -35.385 12.362 1.000 66.619  0 308 HOH B O   1 ? 
HETATM 2568 O O   . HOH F 3 .   ? 35.343 -19.118 27.181 1.000 60.932  0 309 HOH B O   1 ? 
HETATM 2569 O O   . HOH F 3 .   ? 23.380 -38.851 38.155 1.000 53.492  0 310 HOH B O   1 ? 
HETATM 2570 O O   . HOH F 3 .   ? 19.328 -18.193 19.300 1.000 62.637  0 311 HOH B O   1 ? 
HETATM 2571 O O   . HOH F 3 .   ? 34.319 -17.274 25.937 1.000 58.343  0 312 HOH B O   1 ? 
HETATM 2572 O O   . HOH F 3 .   ? 30.387 -14.713 10.929 1.000 62.657  0 313 HOH B O   1 ? 
HETATM 2573 O O   . HOH F 3 .   ? 42.052 -40.982 14.497 1.000 70.229  0 314 HOH B O   1 ? 
HETATM 2574 O O   . HOH F 3 .   ? 46.700 -33.650 18.461 1.000 71.245  0 315 HOH B O   1 ? 
HETATM 2575 O O   . HOH F 3 .   ? 18.727 -11.928 21.280 1.000 67.909  0 316 HOH B O   1 ? 
# 
