data_9EWJ
# 
_entry.id   9EWJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EWJ         pdb_00009ewj 10.2210/pdb9ewj/pdb 
WWPDB D_1292137694 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-16 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EWJ 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              jworrall@essex.ac.uk 
_pdbx_contact_author.name_first         Jonathan 
_pdbx_contact_author.name_last          Worrall 
_pdbx_contact_author.name_mi            A.R. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1863-834X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lucic, M.'       1 ? 
'Worrall, J.A.R.' 2 ? 
'Hough, M.A.'     3 ? 
'Owen, R.L.'      4 ? 
'Strange, R.W.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Dye-decolourising peroxidase DtpB (224 kGy)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lucic, M.'       1 ? 
primary 'Worrall, J.A.R.' 2 ? 
primary 'Hough, M.A.'     3 ? 
primary 'Owen, R.L.'      4 ? 
primary 'Strange, R.W.'   5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Putative dye-decolorizing peroxidase (DyP), encapsulated subgroup' 33759.758 6   ? ? ? ? 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE'                                   616.487   6   ? ? ? ? 
3 non-polymer syn 'MAGNESIUM ION'                                                     24.305    2   ? ? ? ? 
4 non-polymer syn 'OXYGEN ATOM'                                                       15.999    2   ? ? ? ? 
5 non-polymer syn 'TETRAETHYLENE GLYCOL'                                              194.226   1   ? ? ? ? 
6 water       nat water                                                               18.015    243 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGGEVEEPEPQMVLSPLTSAAIFLVVTIDSGGEDTVRDLLSDVASLERAVGFRAQPDGRLSCVTGIGSEAWDRLFSGARP
AGLHPFRELDGPVHRAVATPGDLLFHIRASRLDLCFALATEIMGRLRGAVTPQDEVHGFKYFDERDMLGFVDGTENPTGA
AARRAVLVGAEDPAFAGGSYAVVQKYLHDIDAWEGLSVEAQERVIGRRKMTDVELSDDVKPADSHVALTSVTGPDGSDLE
ILRDNMPFGSVGREEFGTYFIGYARTPEVTETMLERMFLGTASAPHDRILDFSTAVTGSLFFTPAADFLEDL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGGEVEEPEPQMVLSPLTSAAIFLVVTIDSGGEDTVRDLLSDVASLERAVGFRAQPDGRLSCVTGIGSEAWDRLFSGARP
AGLHPFRELDGPVHRAVATPGDLLFHIRASRLDLCFALATEIMGRLRGAVTPQDEVHGFKYFDERDMLGFVDGTENPTGA
AARRAVLVGAEDPAFAGGSYAVVQKYLHDIDAWEGLSVEAQERVIGRRKMTDVELSDDVKPADSHVALTSVTGPDGSDLE
ILRDNMPFGSVGREEFGTYFIGYARTPEVTETMLERMFLGTASAPHDRILDFSTAVTGSLFFTPAADFLEDL
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PROTOPORPHYRIN IX CONTAINING FE' HEM 
3 'MAGNESIUM ION'                   MG  
4 'OXYGEN ATOM'                     O   
5 'TETRAETHYLENE GLYCOL'            PG4 
6 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   GLY n 
1 4   GLU n 
1 5   VAL n 
1 6   GLU n 
1 7   GLU n 
1 8   PRO n 
1 9   GLU n 
1 10  PRO n 
1 11  GLN n 
1 12  MET n 
1 13  VAL n 
1 14  LEU n 
1 15  SER n 
1 16  PRO n 
1 17  LEU n 
1 18  THR n 
1 19  SER n 
1 20  ALA n 
1 21  ALA n 
1 22  ILE n 
1 23  PHE n 
1 24  LEU n 
1 25  VAL n 
1 26  VAL n 
1 27  THR n 
1 28  ILE n 
1 29  ASP n 
1 30  SER n 
1 31  GLY n 
1 32  GLY n 
1 33  GLU n 
1 34  ASP n 
1 35  THR n 
1 36  VAL n 
1 37  ARG n 
1 38  ASP n 
1 39  LEU n 
1 40  LEU n 
1 41  SER n 
1 42  ASP n 
1 43  VAL n 
1 44  ALA n 
1 45  SER n 
1 46  LEU n 
1 47  GLU n 
1 48  ARG n 
1 49  ALA n 
1 50  VAL n 
1 51  GLY n 
1 52  PHE n 
1 53  ARG n 
1 54  ALA n 
1 55  GLN n 
1 56  PRO n 
1 57  ASP n 
1 58  GLY n 
1 59  ARG n 
1 60  LEU n 
1 61  SER n 
1 62  CYS n 
1 63  VAL n 
1 64  THR n 
1 65  GLY n 
1 66  ILE n 
1 67  GLY n 
1 68  SER n 
1 69  GLU n 
1 70  ALA n 
1 71  TRP n 
1 72  ASP n 
1 73  ARG n 
1 74  LEU n 
1 75  PHE n 
1 76  SER n 
1 77  GLY n 
1 78  ALA n 
1 79  ARG n 
1 80  PRO n 
1 81  ALA n 
1 82  GLY n 
1 83  LEU n 
1 84  HIS n 
1 85  PRO n 
1 86  PHE n 
1 87  ARG n 
1 88  GLU n 
1 89  LEU n 
1 90  ASP n 
1 91  GLY n 
1 92  PRO n 
1 93  VAL n 
1 94  HIS n 
1 95  ARG n 
1 96  ALA n 
1 97  VAL n 
1 98  ALA n 
1 99  THR n 
1 100 PRO n 
1 101 GLY n 
1 102 ASP n 
1 103 LEU n 
1 104 LEU n 
1 105 PHE n 
1 106 HIS n 
1 107 ILE n 
1 108 ARG n 
1 109 ALA n 
1 110 SER n 
1 111 ARG n 
1 112 LEU n 
1 113 ASP n 
1 114 LEU n 
1 115 CYS n 
1 116 PHE n 
1 117 ALA n 
1 118 LEU n 
1 119 ALA n 
1 120 THR n 
1 121 GLU n 
1 122 ILE n 
1 123 MET n 
1 124 GLY n 
1 125 ARG n 
1 126 LEU n 
1 127 ARG n 
1 128 GLY n 
1 129 ALA n 
1 130 VAL n 
1 131 THR n 
1 132 PRO n 
1 133 GLN n 
1 134 ASP n 
1 135 GLU n 
1 136 VAL n 
1 137 HIS n 
1 138 GLY n 
1 139 PHE n 
1 140 LYS n 
1 141 TYR n 
1 142 PHE n 
1 143 ASP n 
1 144 GLU n 
1 145 ARG n 
1 146 ASP n 
1 147 MET n 
1 148 LEU n 
1 149 GLY n 
1 150 PHE n 
1 151 VAL n 
1 152 ASP n 
1 153 GLY n 
1 154 THR n 
1 155 GLU n 
1 156 ASN n 
1 157 PRO n 
1 158 THR n 
1 159 GLY n 
1 160 ALA n 
1 161 ALA n 
1 162 ALA n 
1 163 ARG n 
1 164 ARG n 
1 165 ALA n 
1 166 VAL n 
1 167 LEU n 
1 168 VAL n 
1 169 GLY n 
1 170 ALA n 
1 171 GLU n 
1 172 ASP n 
1 173 PRO n 
1 174 ALA n 
1 175 PHE n 
1 176 ALA n 
1 177 GLY n 
1 178 GLY n 
1 179 SER n 
1 180 TYR n 
1 181 ALA n 
1 182 VAL n 
1 183 VAL n 
1 184 GLN n 
1 185 LYS n 
1 186 TYR n 
1 187 LEU n 
1 188 HIS n 
1 189 ASP n 
1 190 ILE n 
1 191 ASP n 
1 192 ALA n 
1 193 TRP n 
1 194 GLU n 
1 195 GLY n 
1 196 LEU n 
1 197 SER n 
1 198 VAL n 
1 199 GLU n 
1 200 ALA n 
1 201 GLN n 
1 202 GLU n 
1 203 ARG n 
1 204 VAL n 
1 205 ILE n 
1 206 GLY n 
1 207 ARG n 
1 208 ARG n 
1 209 LYS n 
1 210 MET n 
1 211 THR n 
1 212 ASP n 
1 213 VAL n 
1 214 GLU n 
1 215 LEU n 
1 216 SER n 
1 217 ASP n 
1 218 ASP n 
1 219 VAL n 
1 220 LYS n 
1 221 PRO n 
1 222 ALA n 
1 223 ASP n 
1 224 SER n 
1 225 HIS n 
1 226 VAL n 
1 227 ALA n 
1 228 LEU n 
1 229 THR n 
1 230 SER n 
1 231 VAL n 
1 232 THR n 
1 233 GLY n 
1 234 PRO n 
1 235 ASP n 
1 236 GLY n 
1 237 SER n 
1 238 ASP n 
1 239 LEU n 
1 240 GLU n 
1 241 ILE n 
1 242 LEU n 
1 243 ARG n 
1 244 ASP n 
1 245 ASN n 
1 246 MET n 
1 247 PRO n 
1 248 PHE n 
1 249 GLY n 
1 250 SER n 
1 251 VAL n 
1 252 GLY n 
1 253 ARG n 
1 254 GLU n 
1 255 GLU n 
1 256 PHE n 
1 257 GLY n 
1 258 THR n 
1 259 TYR n 
1 260 PHE n 
1 261 ILE n 
1 262 GLY n 
1 263 TYR n 
1 264 ALA n 
1 265 ARG n 
1 266 THR n 
1 267 PRO n 
1 268 GLU n 
1 269 VAL n 
1 270 THR n 
1 271 GLU n 
1 272 THR n 
1 273 MET n 
1 274 LEU n 
1 275 GLU n 
1 276 ARG n 
1 277 MET n 
1 278 PHE n 
1 279 LEU n 
1 280 GLY n 
1 281 THR n 
1 282 ALA n 
1 283 SER n 
1 284 ALA n 
1 285 PRO n 
1 286 HIS n 
1 287 ASP n 
1 288 ARG n 
1 289 ILE n 
1 290 LEU n 
1 291 ASP n 
1 292 PHE n 
1 293 SER n 
1 294 THR n 
1 295 ALA n 
1 296 VAL n 
1 297 THR n 
1 298 GLY n 
1 299 SER n 
1 300 LEU n 
1 301 PHE n 
1 302 PHE n 
1 303 THR n 
1 304 PRO n 
1 305 ALA n 
1 306 ALA n 
1 307 ASP n 
1 308 PHE n 
1 309 LEU n 
1 310 GLU n 
1 311 ASP n 
1 312 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   312 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLI_7409 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces lividans 1326' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1200984 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?    'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE                          ?    'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?    'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                             ?    'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                        ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?    'C5 H11 N O2 S'    149.211 
MG  non-polymer         . 'MAGNESIUM ION'                   ?    'Mg 2'             24.305  
O   non-polymer         . 'OXYGEN ATOM'                     ?    O                  15.999  
PG4 non-polymer         . 'TETRAETHYLENE GLYCOL'            ?    'C8 H18 O5'        194.226 
PHE 'L-peptide linking' y PHENYLALANINE                     ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLY 2   2   ?   ?   ?   A . n 
A 1 3   GLY 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   VAL 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   8   PRO PRO A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  PRO 10  10  10  PRO PRO A . n 
A 1 11  GLN 11  11  11  GLN GLN A . n 
A 1 12  MET 12  12  12  MET MET A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  PRO 16  16  16  PRO PRO A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  THR 18  18  18  THR THR A . n 
A 1 19  SER 19  19  19  SER SER A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  ILE 22  22  22  ILE ILE A . n 
A 1 23  PHE 23  23  23  PHE PHE A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  VAL 26  26  26  VAL VAL A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  ASP 29  29  29  ASP ASP A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  ARG 37  37  37  ARG ARG A . n 
A 1 38  ASP 38  38  38  ASP ASP A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  ALA 44  44  44  ALA ALA A . n 
A 1 45  SER 45  45  45  SER SER A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  GLU 47  47  47  GLU GLU A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  GLN 55  55  55  GLN GLN A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  ASP 57  57  57  ASP ASP A . n 
A 1 58  GLY 58  58  58  GLY GLY A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  SER 61  61  61  SER SER A . n 
A 1 62  CYS 62  62  62  CYS CYS A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  ILE 66  66  66  ILE ILE A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  SER 68  68  68  SER SER A . n 
A 1 69  GLU 69  69  69  GLU GLU A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  TRP 71  71  71  TRP TRP A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  SER 76  76  76  SER SER A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  HIS 84  84  84  HIS HIS A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  PHE 86  86  86  PHE PHE A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  GLU 88  88  88  GLU GLU A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ASP 90  90  90  ASP ASP A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  PRO 92  92  92  PRO PRO A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  HIS 94  94  94  HIS HIS A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  THR 99  99  99  THR THR A . n 
A 1 100 PRO 100 100 100 PRO PRO A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 ASP 102 102 102 ASP ASP A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 HIS 106 106 106 HIS HIS A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 SER 110 110 110 SER SER A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 CYS 115 115 115 CYS CYS A . n 
A 1 116 PHE 116 116 116 PHE PHE A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 ILE 122 122 122 ILE ILE A . n 
A 1 123 MET 123 123 123 MET MET A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 PRO 132 132 132 PRO PRO A . n 
A 1 133 GLN 133 133 133 GLN GLN A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 GLU 135 135 135 GLU GLU A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 HIS 137 137 137 HIS HIS A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 TYR 141 141 141 TYR TYR A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 ARG 145 145 145 ARG ARG A . n 
A 1 146 ASP 146 146 146 ASP ASP A . n 
A 1 147 MET 147 147 147 MET MET A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 ASP 152 152 152 ASP ASP A . n 
A 1 153 GLY 153 153 153 GLY GLY A . n 
A 1 154 THR 154 154 154 THR THR A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 PRO 157 157 157 PRO PRO A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 GLY 159 159 159 GLY GLY A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 ALA 162 162 162 ALA ALA A . n 
A 1 163 ARG 163 163 163 ARG ARG A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 GLY 169 169 169 GLY GLY A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 GLU 171 171 171 GLU GLU A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 PRO 173 173 173 PRO PRO A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 PHE 175 175 175 PHE PHE A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 TYR 180 180 180 TYR TYR A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 GLN 184 184 184 GLN GLN A . n 
A 1 185 LYS 185 185 185 LYS LYS A . n 
A 1 186 TYR 186 186 186 TYR TYR A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 HIS 188 188 188 HIS HIS A . n 
A 1 189 ASP 189 189 189 ASP ASP A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 ASP 191 191 191 ASP ASP A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 TRP 193 193 193 TRP TRP A . n 
A 1 194 GLU 194 194 194 GLU GLU A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 GLU 199 199 199 GLU GLU A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 GLN 201 201 201 GLN GLN A . n 
A 1 202 GLU 202 202 202 GLU GLU A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 ILE 205 205 205 ILE ILE A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 ARG 208 208 208 ARG ARG A . n 
A 1 209 LYS 209 209 209 LYS LYS A . n 
A 1 210 MET 210 210 210 MET MET A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 ASP 212 212 212 ASP ASP A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 PRO 221 221 221 PRO PRO A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 ASP 223 223 223 ASP ASP A . n 
A 1 224 SER 224 224 224 SER SER A . n 
A 1 225 HIS 225 225 225 HIS HIS A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 ALA 227 227 227 ALA ALA A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 THR 229 229 229 THR THR A . n 
A 1 230 SER 230 230 230 SER SER A . n 
A 1 231 VAL 231 231 231 VAL VAL A . n 
A 1 232 THR 232 232 232 THR THR A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 PRO 234 234 234 PRO PRO A . n 
A 1 235 ASP 235 235 235 ASP ASP A . n 
A 1 236 GLY 236 236 236 GLY GLY A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 ASP 238 238 238 ASP ASP A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 ASP 244 244 244 ASP ASP A . n 
A 1 245 ASN 245 245 245 ASN ASN A . n 
A 1 246 MET 246 246 246 MET MET A . n 
A 1 247 PRO 247 247 247 PRO PRO A . n 
A 1 248 PHE 248 248 248 PHE PHE A . n 
A 1 249 GLY 249 249 249 GLY GLY A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 GLY 252 252 252 GLY GLY A . n 
A 1 253 ARG 253 253 253 ARG ARG A . n 
A 1 254 GLU 254 254 254 GLU GLU A . n 
A 1 255 GLU 255 255 255 GLU GLU A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 GLY 257 257 257 GLY GLY A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 TYR 259 259 259 TYR TYR A . n 
A 1 260 PHE 260 260 260 PHE PHE A . n 
A 1 261 ILE 261 261 261 ILE ILE A . n 
A 1 262 GLY 262 262 262 GLY GLY A . n 
A 1 263 TYR 263 263 263 TYR TYR A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ARG 265 265 265 ARG ARG A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 VAL 269 269 269 VAL VAL A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 GLU 271 271 271 GLU GLU A . n 
A 1 272 THR 272 272 272 THR THR A . n 
A 1 273 MET 273 273 273 MET MET A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 MET 277 277 277 MET MET A . n 
A 1 278 PHE 278 278 278 PHE PHE A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 ALA 284 284 284 ALA ALA A . n 
A 1 285 PRO 285 285 285 PRO PRO A . n 
A 1 286 HIS 286 286 286 HIS HIS A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 ARG 288 288 288 ARG ARG A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 ASP 291 291 291 ASP ASP A . n 
A 1 292 PHE 292 292 292 PHE PHE A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 THR 294 294 294 THR THR A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 GLY 298 298 298 GLY GLY A . n 
A 1 299 SER 299 299 299 SER SER A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 PHE 301 301 301 PHE PHE A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 PHE 308 308 308 PHE PHE A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 GLU 310 310 310 GLU GLU A . n 
A 1 311 ASP 311 311 311 ASP ASP A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLY 2   2   ?   ?   ?   B . n 
B 1 3   GLY 3   3   ?   ?   ?   B . n 
B 1 4   GLU 4   4   ?   ?   ?   B . n 
B 1 5   VAL 5   5   ?   ?   ?   B . n 
B 1 6   GLU 6   6   ?   ?   ?   B . n 
B 1 7   GLU 7   7   7   GLU GLU B . n 
B 1 8   PRO 8   8   8   PRO PRO B . n 
B 1 9   GLU 9   9   9   GLU GLU B . n 
B 1 10  PRO 10  10  10  PRO PRO B . n 
B 1 11  GLN 11  11  11  GLN GLN B . n 
B 1 12  MET 12  12  12  MET MET B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  PRO 16  16  16  PRO PRO B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  THR 18  18  18  THR THR B . n 
B 1 19  SER 19  19  19  SER SER B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  ILE 22  22  22  ILE ILE B . n 
B 1 23  PHE 23  23  23  PHE PHE B . n 
B 1 24  LEU 24  24  24  LEU LEU B . n 
B 1 25  VAL 25  25  25  VAL VAL B . n 
B 1 26  VAL 26  26  26  VAL VAL B . n 
B 1 27  THR 27  27  27  THR THR B . n 
B 1 28  ILE 28  28  28  ILE ILE B . n 
B 1 29  ASP 29  29  29  ASP ASP B . n 
B 1 30  SER 30  30  30  SER SER B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  THR 35  35  35  THR THR B . n 
B 1 36  VAL 36  36  36  VAL VAL B . n 
B 1 37  ARG 37  37  37  ARG ARG B . n 
B 1 38  ASP 38  38  38  ASP ASP B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  LEU 40  40  40  LEU LEU B . n 
B 1 41  SER 41  41  41  SER SER B . n 
B 1 42  ASP 42  42  42  ASP ASP B . n 
B 1 43  VAL 43  43  43  VAL VAL B . n 
B 1 44  ALA 44  44  44  ALA ALA B . n 
B 1 45  SER 45  45  45  SER SER B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  GLU 47  47  47  GLU GLU B . n 
B 1 48  ARG 48  48  48  ARG ARG B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  VAL 50  50  50  VAL VAL B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  ARG 53  53  53  ARG ARG B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  GLN 55  55  55  GLN GLN B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  ASP 57  57  57  ASP ASP B . n 
B 1 58  GLY 58  58  58  GLY GLY B . n 
B 1 59  ARG 59  59  59  ARG ARG B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  SER 61  61  61  SER SER B . n 
B 1 62  CYS 62  62  62  CYS CYS B . n 
B 1 63  VAL 63  63  63  VAL VAL B . n 
B 1 64  THR 64  64  64  THR THR B . n 
B 1 65  GLY 65  65  65  GLY GLY B . n 
B 1 66  ILE 66  66  66  ILE ILE B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  SER 68  68  68  SER SER B . n 
B 1 69  GLU 69  69  69  GLU GLU B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  TRP 71  71  71  TRP TRP B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  PHE 75  75  75  PHE PHE B . n 
B 1 76  SER 76  76  76  SER SER B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  PRO 80  80  80  PRO PRO B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  GLY 82  82  82  GLY GLY B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  HIS 84  84  84  HIS HIS B . n 
B 1 85  PRO 85  85  85  PRO PRO B . n 
B 1 86  PHE 86  86  86  PHE PHE B . n 
B 1 87  ARG 87  87  87  ARG ARG B . n 
B 1 88  GLU 88  88  88  GLU GLU B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  ASP 90  90  90  ASP ASP B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  PRO 92  92  92  PRO PRO B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  HIS 94  94  94  HIS HIS B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  ALA 96  96  96  ALA ALA B . n 
B 1 97  VAL 97  97  97  VAL VAL B . n 
B 1 98  ALA 98  98  98  ALA ALA B . n 
B 1 99  THR 99  99  99  THR THR B . n 
B 1 100 PRO 100 100 100 PRO PRO B . n 
B 1 101 GLY 101 101 101 GLY GLY B . n 
B 1 102 ASP 102 102 102 ASP ASP B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 HIS 106 106 106 HIS HIS B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 ARG 108 108 108 ARG ARG B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 SER 110 110 110 SER SER B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 LEU 112 112 112 LEU LEU B . n 
B 1 113 ASP 113 113 113 ASP ASP B . n 
B 1 114 LEU 114 114 114 LEU LEU B . n 
B 1 115 CYS 115 115 115 CYS CYS B . n 
B 1 116 PHE 116 116 116 PHE PHE B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 GLU 121 121 121 GLU GLU B . n 
B 1 122 ILE 122 122 122 ILE ILE B . n 
B 1 123 MET 123 123 123 MET MET B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 ARG 125 125 125 ARG ARG B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 ARG 127 127 127 ARG ARG B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 PRO 132 132 132 PRO PRO B . n 
B 1 133 GLN 133 133 133 GLN GLN B . n 
B 1 134 ASP 134 134 134 ASP ASP B . n 
B 1 135 GLU 135 135 135 GLU GLU B . n 
B 1 136 VAL 136 136 136 VAL VAL B . n 
B 1 137 HIS 137 137 137 HIS HIS B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 TYR 141 141 141 TYR TYR B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ASP 143 143 143 ASP ASP B . n 
B 1 144 GLU 144 144 144 GLU GLU B . n 
B 1 145 ARG 145 145 145 ARG ARG B . n 
B 1 146 ASP 146 146 146 ASP ASP B . n 
B 1 147 MET 147 147 147 MET MET B . n 
B 1 148 LEU 148 148 148 LEU LEU B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 VAL 151 151 151 VAL VAL B . n 
B 1 152 ASP 152 152 152 ASP ASP B . n 
B 1 153 GLY 153 153 153 GLY GLY B . n 
B 1 154 THR 154 154 154 THR THR B . n 
B 1 155 GLU 155 155 155 GLU GLU B . n 
B 1 156 ASN 156 156 156 ASN ASN B . n 
B 1 157 PRO 157 157 157 PRO PRO B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 GLY 159 159 159 GLY GLY B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 ALA 161 161 161 ALA ALA B . n 
B 1 162 ALA 162 162 162 ALA ALA B . n 
B 1 163 ARG 163 163 163 ARG ARG B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 ALA 165 165 165 ALA ALA B . n 
B 1 166 VAL 166 166 166 VAL VAL B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 VAL 168 168 168 VAL VAL B . n 
B 1 169 GLY 169 169 169 GLY GLY B . n 
B 1 170 ALA 170 170 170 ALA ALA B . n 
B 1 171 GLU 171 171 171 GLU GLU B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 PRO 173 173 173 PRO PRO B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 PHE 175 175 175 PHE PHE B . n 
B 1 176 ALA 176 176 176 ALA ALA B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 SER 179 179 179 SER SER B . n 
B 1 180 TYR 180 180 180 TYR TYR B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 VAL 183 183 183 VAL VAL B . n 
B 1 184 GLN 184 184 184 GLN GLN B . n 
B 1 185 LYS 185 185 185 LYS LYS B . n 
B 1 186 TYR 186 186 186 TYR TYR B . n 
B 1 187 LEU 187 187 187 LEU LEU B . n 
B 1 188 HIS 188 188 188 HIS HIS B . n 
B 1 189 ASP 189 189 189 ASP ASP B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 ASP 191 191 191 ASP ASP B . n 
B 1 192 ALA 192 192 192 ALA ALA B . n 
B 1 193 TRP 193 193 193 TRP TRP B . n 
B 1 194 GLU 194 194 194 GLU GLU B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 LEU 196 196 196 LEU LEU B . n 
B 1 197 SER 197 197 197 SER SER B . n 
B 1 198 VAL 198 198 198 VAL VAL B . n 
B 1 199 GLU 199 199 199 GLU GLU B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 GLN 201 201 201 GLN GLN B . n 
B 1 202 GLU 202 202 202 GLU GLU B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 ILE 205 205 205 ILE ILE B . n 
B 1 206 GLY 206 206 206 GLY GLY B . n 
B 1 207 ARG 207 207 207 ARG ARG B . n 
B 1 208 ARG 208 208 208 ARG ARG B . n 
B 1 209 LYS 209 209 209 LYS LYS B . n 
B 1 210 MET 210 210 210 MET MET B . n 
B 1 211 THR 211 211 211 THR THR B . n 
B 1 212 ASP 212 212 212 ASP ASP B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 GLU 214 214 214 GLU GLU B . n 
B 1 215 LEU 215 215 215 LEU LEU B . n 
B 1 216 SER 216 216 216 SER SER B . n 
B 1 217 ASP 217 217 217 ASP ASP B . n 
B 1 218 ASP 218 218 218 ASP ASP B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 LYS 220 220 220 LYS LYS B . n 
B 1 221 PRO 221 221 221 PRO PRO B . n 
B 1 222 ALA 222 222 222 ALA ALA B . n 
B 1 223 ASP 223 223 223 ASP ASP B . n 
B 1 224 SER 224 224 224 SER SER B . n 
B 1 225 HIS 225 225 225 HIS HIS B . n 
B 1 226 VAL 226 226 226 VAL VAL B . n 
B 1 227 ALA 227 227 227 ALA ALA B . n 
B 1 228 LEU 228 228 228 LEU LEU B . n 
B 1 229 THR 229 229 229 THR THR B . n 
B 1 230 SER 230 230 230 SER SER B . n 
B 1 231 VAL 231 231 231 VAL VAL B . n 
B 1 232 THR 232 232 232 THR THR B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 PRO 234 234 234 PRO PRO B . n 
B 1 235 ASP 235 235 235 ASP ASP B . n 
B 1 236 GLY 236 236 236 GLY GLY B . n 
B 1 237 SER 237 237 237 SER SER B . n 
B 1 238 ASP 238 238 238 ASP ASP B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 ARG 243 243 243 ARG ARG B . n 
B 1 244 ASP 244 244 244 ASP ASP B . n 
B 1 245 ASN 245 245 245 ASN ASN B . n 
B 1 246 MET 246 246 246 MET MET B . n 
B 1 247 PRO 247 247 247 PRO PRO B . n 
B 1 248 PHE 248 248 248 PHE PHE B . n 
B 1 249 GLY 249 249 249 GLY GLY B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 VAL 251 251 251 VAL VAL B . n 
B 1 252 GLY 252 252 252 GLY GLY B . n 
B 1 253 ARG 253 253 253 ARG ARG B . n 
B 1 254 GLU 254 254 254 GLU GLU B . n 
B 1 255 GLU 255 255 255 GLU GLU B . n 
B 1 256 PHE 256 256 256 PHE PHE B . n 
B 1 257 GLY 257 257 257 GLY GLY B . n 
B 1 258 THR 258 258 258 THR THR B . n 
B 1 259 TYR 259 259 259 TYR TYR B . n 
B 1 260 PHE 260 260 260 PHE PHE B . n 
B 1 261 ILE 261 261 261 ILE ILE B . n 
B 1 262 GLY 262 262 262 GLY GLY B . n 
B 1 263 TYR 263 263 263 TYR TYR B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ARG 265 265 265 ARG ARG B . n 
B 1 266 THR 266 266 266 THR THR B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 GLU 268 268 268 GLU GLU B . n 
B 1 269 VAL 269 269 269 VAL VAL B . n 
B 1 270 THR 270 270 270 THR THR B . n 
B 1 271 GLU 271 271 271 GLU GLU B . n 
B 1 272 THR 272 272 272 THR THR B . n 
B 1 273 MET 273 273 273 MET MET B . n 
B 1 274 LEU 274 274 274 LEU LEU B . n 
B 1 275 GLU 275 275 275 GLU GLU B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 MET 277 277 277 MET MET B . n 
B 1 278 PHE 278 278 278 PHE PHE B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 GLY 280 280 280 GLY GLY B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 ALA 284 284 284 ALA ALA B . n 
B 1 285 PRO 285 285 285 PRO PRO B . n 
B 1 286 HIS 286 286 286 HIS HIS B . n 
B 1 287 ASP 287 287 287 ASP ASP B . n 
B 1 288 ARG 288 288 288 ARG ARG B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 LEU 290 290 290 LEU LEU B . n 
B 1 291 ASP 291 291 291 ASP ASP B . n 
B 1 292 PHE 292 292 292 PHE PHE B . n 
B 1 293 SER 293 293 293 SER SER B . n 
B 1 294 THR 294 294 294 THR THR B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 GLY 298 298 298 GLY GLY B . n 
B 1 299 SER 299 299 299 SER SER B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 PHE 301 301 301 PHE PHE B . n 
B 1 302 PHE 302 302 302 PHE PHE B . n 
B 1 303 THR 303 303 303 THR THR B . n 
B 1 304 PRO 304 304 304 PRO PRO B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 PHE 308 308 308 PHE PHE B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 GLU 310 310 310 GLU GLU B . n 
B 1 311 ASP 311 311 311 ASP ASP B . n 
B 1 312 LEU 312 312 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   GLY 2   2   ?   ?   ?   C . n 
C 1 3   GLY 3   3   ?   ?   ?   C . n 
C 1 4   GLU 4   4   ?   ?   ?   C . n 
C 1 5   VAL 5   5   ?   ?   ?   C . n 
C 1 6   GLU 6   6   ?   ?   ?   C . n 
C 1 7   GLU 7   7   7   GLU GLU C . n 
C 1 8   PRO 8   8   8   PRO PRO C . n 
C 1 9   GLU 9   9   9   GLU GLU C . n 
C 1 10  PRO 10  10  10  PRO PRO C . n 
C 1 11  GLN 11  11  11  GLN GLN C . n 
C 1 12  MET 12  12  12  MET MET C . n 
C 1 13  VAL 13  13  13  VAL VAL C . n 
C 1 14  LEU 14  14  14  LEU LEU C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  PRO 16  16  16  PRO PRO C . n 
C 1 17  LEU 17  17  17  LEU LEU C . n 
C 1 18  THR 18  18  18  THR THR C . n 
C 1 19  SER 19  19  19  SER SER C . n 
C 1 20  ALA 20  20  20  ALA ALA C . n 
C 1 21  ALA 21  21  21  ALA ALA C . n 
C 1 22  ILE 22  22  22  ILE ILE C . n 
C 1 23  PHE 23  23  23  PHE PHE C . n 
C 1 24  LEU 24  24  24  LEU LEU C . n 
C 1 25  VAL 25  25  25  VAL VAL C . n 
C 1 26  VAL 26  26  26  VAL VAL C . n 
C 1 27  THR 27  27  27  THR THR C . n 
C 1 28  ILE 28  28  28  ILE ILE C . n 
C 1 29  ASP 29  29  29  ASP ASP C . n 
C 1 30  SER 30  30  30  SER SER C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  GLY 32  32  32  GLY GLY C . n 
C 1 33  GLU 33  33  33  GLU GLU C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  THR 35  35  35  THR THR C . n 
C 1 36  VAL 36  36  36  VAL VAL C . n 
C 1 37  ARG 37  37  37  ARG ARG C . n 
C 1 38  ASP 38  38  38  ASP ASP C . n 
C 1 39  LEU 39  39  39  LEU LEU C . n 
C 1 40  LEU 40  40  40  LEU LEU C . n 
C 1 41  SER 41  41  41  SER SER C . n 
C 1 42  ASP 42  42  42  ASP ASP C . n 
C 1 43  VAL 43  43  43  VAL VAL C . n 
C 1 44  ALA 44  44  44  ALA ALA C . n 
C 1 45  SER 45  45  45  SER SER C . n 
C 1 46  LEU 46  46  46  LEU LEU C . n 
C 1 47  GLU 47  47  47  GLU GLU C . n 
C 1 48  ARG 48  48  48  ARG ARG C . n 
C 1 49  ALA 49  49  49  ALA ALA C . n 
C 1 50  VAL 50  50  50  VAL VAL C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  ARG 53  53  53  ARG ARG C . n 
C 1 54  ALA 54  54  54  ALA ALA C . n 
C 1 55  GLN 55  55  55  GLN GLN C . n 
C 1 56  PRO 56  56  56  PRO PRO C . n 
C 1 57  ASP 57  57  57  ASP ASP C . n 
C 1 58  GLY 58  58  58  GLY GLY C . n 
C 1 59  ARG 59  59  59  ARG ARG C . n 
C 1 60  LEU 60  60  60  LEU LEU C . n 
C 1 61  SER 61  61  61  SER SER C . n 
C 1 62  CYS 62  62  62  CYS CYS C . n 
C 1 63  VAL 63  63  63  VAL VAL C . n 
C 1 64  THR 64  64  64  THR THR C . n 
C 1 65  GLY 65  65  65  GLY GLY C . n 
C 1 66  ILE 66  66  66  ILE ILE C . n 
C 1 67  GLY 67  67  67  GLY GLY C . n 
C 1 68  SER 68  68  68  SER SER C . n 
C 1 69  GLU 69  69  69  GLU GLU C . n 
C 1 70  ALA 70  70  70  ALA ALA C . n 
C 1 71  TRP 71  71  71  TRP TRP C . n 
C 1 72  ASP 72  72  72  ASP ASP C . n 
C 1 73  ARG 73  73  73  ARG ARG C . n 
C 1 74  LEU 74  74  74  LEU LEU C . n 
C 1 75  PHE 75  75  75  PHE PHE C . n 
C 1 76  SER 76  76  76  SER SER C . n 
C 1 77  GLY 77  77  77  GLY GLY C . n 
C 1 78  ALA 78  78  78  ALA ALA C . n 
C 1 79  ARG 79  79  79  ARG ARG C . n 
C 1 80  PRO 80  80  80  PRO PRO C . n 
C 1 81  ALA 81  81  81  ALA ALA C . n 
C 1 82  GLY 82  82  82  GLY GLY C . n 
C 1 83  LEU 83  83  83  LEU LEU C . n 
C 1 84  HIS 84  84  84  HIS HIS C . n 
C 1 85  PRO 85  85  85  PRO PRO C . n 
C 1 86  PHE 86  86  86  PHE PHE C . n 
C 1 87  ARG 87  87  87  ARG ARG C . n 
C 1 88  GLU 88  88  88  GLU GLU C . n 
C 1 89  LEU 89  89  89  LEU LEU C . n 
C 1 90  ASP 90  90  90  ASP ASP C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  PRO 92  92  92  PRO PRO C . n 
C 1 93  VAL 93  93  93  VAL VAL C . n 
C 1 94  HIS 94  94  94  HIS HIS C . n 
C 1 95  ARG 95  95  95  ARG ARG C . n 
C 1 96  ALA 96  96  96  ALA ALA C . n 
C 1 97  VAL 97  97  97  VAL VAL C . n 
C 1 98  ALA 98  98  98  ALA ALA C . n 
C 1 99  THR 99  99  99  THR THR C . n 
C 1 100 PRO 100 100 100 PRO PRO C . n 
C 1 101 GLY 101 101 101 GLY GLY C . n 
C 1 102 ASP 102 102 102 ASP ASP C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 LEU 104 104 104 LEU LEU C . n 
C 1 105 PHE 105 105 105 PHE PHE C . n 
C 1 106 HIS 106 106 106 HIS HIS C . n 
C 1 107 ILE 107 107 107 ILE ILE C . n 
C 1 108 ARG 108 108 108 ARG ARG C . n 
C 1 109 ALA 109 109 109 ALA ALA C . n 
C 1 110 SER 110 110 110 SER SER C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 LEU 112 112 112 LEU LEU C . n 
C 1 113 ASP 113 113 113 ASP ASP C . n 
C 1 114 LEU 114 114 114 LEU LEU C . n 
C 1 115 CYS 115 115 115 CYS CYS C . n 
C 1 116 PHE 116 116 116 PHE PHE C . n 
C 1 117 ALA 117 117 117 ALA ALA C . n 
C 1 118 LEU 118 118 118 LEU LEU C . n 
C 1 119 ALA 119 119 119 ALA ALA C . n 
C 1 120 THR 120 120 120 THR THR C . n 
C 1 121 GLU 121 121 121 GLU GLU C . n 
C 1 122 ILE 122 122 122 ILE ILE C . n 
C 1 123 MET 123 123 123 MET MET C . n 
C 1 124 GLY 124 124 124 GLY GLY C . n 
C 1 125 ARG 125 125 125 ARG ARG C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 ARG 127 127 127 ARG ARG C . n 
C 1 128 GLY 128 128 128 GLY GLY C . n 
C 1 129 ALA 129 129 129 ALA ALA C . n 
C 1 130 VAL 130 130 130 VAL VAL C . n 
C 1 131 THR 131 131 131 THR THR C . n 
C 1 132 PRO 132 132 132 PRO PRO C . n 
C 1 133 GLN 133 133 133 GLN GLN C . n 
C 1 134 ASP 134 134 134 ASP ASP C . n 
C 1 135 GLU 135 135 135 GLU GLU C . n 
C 1 136 VAL 136 136 136 VAL VAL C . n 
C 1 137 HIS 137 137 137 HIS HIS C . n 
C 1 138 GLY 138 138 138 GLY GLY C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 LYS 140 140 140 LYS LYS C . n 
C 1 141 TYR 141 141 141 TYR TYR C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 ASP 143 143 143 ASP ASP C . n 
C 1 144 GLU 144 144 144 GLU GLU C . n 
C 1 145 ARG 145 145 145 ARG ARG C . n 
C 1 146 ASP 146 146 146 ASP ASP C . n 
C 1 147 MET 147 147 147 MET MET C . n 
C 1 148 LEU 148 148 148 LEU LEU C . n 
C 1 149 GLY 149 149 149 GLY GLY C . n 
C 1 150 PHE 150 150 150 PHE PHE C . n 
C 1 151 VAL 151 151 151 VAL VAL C . n 
C 1 152 ASP 152 152 152 ASP ASP C . n 
C 1 153 GLY 153 153 153 GLY GLY C . n 
C 1 154 THR 154 154 154 THR THR C . n 
C 1 155 GLU 155 155 155 GLU GLU C . n 
C 1 156 ASN 156 156 156 ASN ASN C . n 
C 1 157 PRO 157 157 157 PRO PRO C . n 
C 1 158 THR 158 158 158 THR THR C . n 
C 1 159 GLY 159 159 159 GLY GLY C . n 
C 1 160 ALA 160 160 160 ALA ALA C . n 
C 1 161 ALA 161 161 161 ALA ALA C . n 
C 1 162 ALA 162 162 162 ALA ALA C . n 
C 1 163 ARG 163 163 163 ARG ARG C . n 
C 1 164 ARG 164 164 164 ARG ARG C . n 
C 1 165 ALA 165 165 165 ALA ALA C . n 
C 1 166 VAL 166 166 166 VAL VAL C . n 
C 1 167 LEU 167 167 167 LEU LEU C . n 
C 1 168 VAL 168 168 168 VAL VAL C . n 
C 1 169 GLY 169 169 169 GLY GLY C . n 
C 1 170 ALA 170 170 170 ALA ALA C . n 
C 1 171 GLU 171 171 171 GLU GLU C . n 
C 1 172 ASP 172 172 172 ASP ASP C . n 
C 1 173 PRO 173 173 173 PRO PRO C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 PHE 175 175 175 PHE PHE C . n 
C 1 176 ALA 176 176 176 ALA ALA C . n 
C 1 177 GLY 177 177 177 GLY GLY C . n 
C 1 178 GLY 178 178 178 GLY GLY C . n 
C 1 179 SER 179 179 179 SER SER C . n 
C 1 180 TYR 180 180 180 TYR TYR C . n 
C 1 181 ALA 181 181 181 ALA ALA C . n 
C 1 182 VAL 182 182 182 VAL VAL C . n 
C 1 183 VAL 183 183 183 VAL VAL C . n 
C 1 184 GLN 184 184 184 GLN GLN C . n 
C 1 185 LYS 185 185 185 LYS LYS C . n 
C 1 186 TYR 186 186 186 TYR TYR C . n 
C 1 187 LEU 187 187 187 LEU LEU C . n 
C 1 188 HIS 188 188 188 HIS HIS C . n 
C 1 189 ASP 189 189 189 ASP ASP C . n 
C 1 190 ILE 190 190 190 ILE ILE C . n 
C 1 191 ASP 191 191 191 ASP ASP C . n 
C 1 192 ALA 192 192 192 ALA ALA C . n 
C 1 193 TRP 193 193 193 TRP TRP C . n 
C 1 194 GLU 194 194 194 GLU GLU C . n 
C 1 195 GLY 195 195 195 GLY GLY C . n 
C 1 196 LEU 196 196 196 LEU LEU C . n 
C 1 197 SER 197 197 197 SER SER C . n 
C 1 198 VAL 198 198 198 VAL VAL C . n 
C 1 199 GLU 199 199 199 GLU GLU C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 GLN 201 201 201 GLN GLN C . n 
C 1 202 GLU 202 202 202 GLU GLU C . n 
C 1 203 ARG 203 203 203 ARG ARG C . n 
C 1 204 VAL 204 204 204 VAL VAL C . n 
C 1 205 ILE 205 205 205 ILE ILE C . n 
C 1 206 GLY 206 206 206 GLY GLY C . n 
C 1 207 ARG 207 207 207 ARG ARG C . n 
C 1 208 ARG 208 208 208 ARG ARG C . n 
C 1 209 LYS 209 209 209 LYS LYS C . n 
C 1 210 MET 210 210 210 MET MET C . n 
C 1 211 THR 211 211 211 THR THR C . n 
C 1 212 ASP 212 212 212 ASP ASP C . n 
C 1 213 VAL 213 213 213 VAL VAL C . n 
C 1 214 GLU 214 214 214 GLU GLU C . n 
C 1 215 LEU 215 215 215 LEU LEU C . n 
C 1 216 SER 216 216 216 SER SER C . n 
C 1 217 ASP 217 217 217 ASP ASP C . n 
C 1 218 ASP 218 218 218 ASP ASP C . n 
C 1 219 VAL 219 219 219 VAL VAL C . n 
C 1 220 LYS 220 220 220 LYS LYS C . n 
C 1 221 PRO 221 221 221 PRO PRO C . n 
C 1 222 ALA 222 222 222 ALA ALA C . n 
C 1 223 ASP 223 223 223 ASP ASP C . n 
C 1 224 SER 224 224 224 SER SER C . n 
C 1 225 HIS 225 225 225 HIS HIS C . n 
C 1 226 VAL 226 226 226 VAL VAL C . n 
C 1 227 ALA 227 227 227 ALA ALA C . n 
C 1 228 LEU 228 228 228 LEU LEU C . n 
C 1 229 THR 229 229 229 THR THR C . n 
C 1 230 SER 230 230 230 SER SER C . n 
C 1 231 VAL 231 231 231 VAL VAL C . n 
C 1 232 THR 232 232 232 THR THR C . n 
C 1 233 GLY 233 233 233 GLY GLY C . n 
C 1 234 PRO 234 234 234 PRO PRO C . n 
C 1 235 ASP 235 235 235 ASP ASP C . n 
C 1 236 GLY 236 236 236 GLY GLY C . n 
C 1 237 SER 237 237 237 SER SER C . n 
C 1 238 ASP 238 238 238 ASP ASP C . n 
C 1 239 LEU 239 239 239 LEU LEU C . n 
C 1 240 GLU 240 240 240 GLU GLU C . n 
C 1 241 ILE 241 241 241 ILE ILE C . n 
C 1 242 LEU 242 242 242 LEU LEU C . n 
C 1 243 ARG 243 243 243 ARG ARG C . n 
C 1 244 ASP 244 244 244 ASP ASP C . n 
C 1 245 ASN 245 245 245 ASN ASN C . n 
C 1 246 MET 246 246 246 MET MET C . n 
C 1 247 PRO 247 247 247 PRO PRO C . n 
C 1 248 PHE 248 248 248 PHE PHE C . n 
C 1 249 GLY 249 249 249 GLY GLY C . n 
C 1 250 SER 250 250 250 SER SER C . n 
C 1 251 VAL 251 251 251 VAL VAL C . n 
C 1 252 GLY 252 252 252 GLY GLY C . n 
C 1 253 ARG 253 253 253 ARG ARG C . n 
C 1 254 GLU 254 254 254 GLU GLU C . n 
C 1 255 GLU 255 255 255 GLU GLU C . n 
C 1 256 PHE 256 256 256 PHE PHE C . n 
C 1 257 GLY 257 257 257 GLY GLY C . n 
C 1 258 THR 258 258 258 THR THR C . n 
C 1 259 TYR 259 259 259 TYR TYR C . n 
C 1 260 PHE 260 260 260 PHE PHE C . n 
C 1 261 ILE 261 261 261 ILE ILE C . n 
C 1 262 GLY 262 262 262 GLY GLY C . n 
C 1 263 TYR 263 263 263 TYR TYR C . n 
C 1 264 ALA 264 264 264 ALA ALA C . n 
C 1 265 ARG 265 265 265 ARG ARG C . n 
C 1 266 THR 266 266 266 THR THR C . n 
C 1 267 PRO 267 267 267 PRO PRO C . n 
C 1 268 GLU 268 268 268 GLU GLU C . n 
C 1 269 VAL 269 269 269 VAL VAL C . n 
C 1 270 THR 270 270 270 THR THR C . n 
C 1 271 GLU 271 271 271 GLU GLU C . n 
C 1 272 THR 272 272 272 THR THR C . n 
C 1 273 MET 273 273 273 MET MET C . n 
C 1 274 LEU 274 274 274 LEU LEU C . n 
C 1 275 GLU 275 275 275 GLU GLU C . n 
C 1 276 ARG 276 276 276 ARG ARG C . n 
C 1 277 MET 277 277 277 MET MET C . n 
C 1 278 PHE 278 278 278 PHE PHE C . n 
C 1 279 LEU 279 279 279 LEU LEU C . n 
C 1 280 GLY 280 280 280 GLY GLY C . n 
C 1 281 THR 281 281 281 THR THR C . n 
C 1 282 ALA 282 282 282 ALA ALA C . n 
C 1 283 SER 283 283 283 SER SER C . n 
C 1 284 ALA 284 284 284 ALA ALA C . n 
C 1 285 PRO 285 285 285 PRO PRO C . n 
C 1 286 HIS 286 286 286 HIS HIS C . n 
C 1 287 ASP 287 287 287 ASP ASP C . n 
C 1 288 ARG 288 288 288 ARG ARG C . n 
C 1 289 ILE 289 289 289 ILE ILE C . n 
C 1 290 LEU 290 290 290 LEU LEU C . n 
C 1 291 ASP 291 291 291 ASP ASP C . n 
C 1 292 PHE 292 292 292 PHE PHE C . n 
C 1 293 SER 293 293 293 SER SER C . n 
C 1 294 THR 294 294 294 THR THR C . n 
C 1 295 ALA 295 295 295 ALA ALA C . n 
C 1 296 VAL 296 296 296 VAL VAL C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 GLY 298 298 298 GLY GLY C . n 
C 1 299 SER 299 299 299 SER SER C . n 
C 1 300 LEU 300 300 300 LEU LEU C . n 
C 1 301 PHE 301 301 301 PHE PHE C . n 
C 1 302 PHE 302 302 302 PHE PHE C . n 
C 1 303 THR 303 303 303 THR THR C . n 
C 1 304 PRO 304 304 304 PRO PRO C . n 
C 1 305 ALA 305 305 305 ALA ALA C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 ASP 307 307 307 ASP ASP C . n 
C 1 308 PHE 308 308 308 PHE PHE C . n 
C 1 309 LEU 309 309 309 LEU LEU C . n 
C 1 310 GLU 310 310 310 GLU GLU C . n 
C 1 311 ASP 311 311 311 ASP ASP C . n 
C 1 312 LEU 312 312 312 LEU LEU C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   GLY 2   2   ?   ?   ?   D . n 
D 1 3   GLY 3   3   ?   ?   ?   D . n 
D 1 4   GLU 4   4   ?   ?   ?   D . n 
D 1 5   VAL 5   5   ?   ?   ?   D . n 
D 1 6   GLU 6   6   ?   ?   ?   D . n 
D 1 7   GLU 7   7   7   GLU GLU D . n 
D 1 8   PRO 8   8   8   PRO PRO D . n 
D 1 9   GLU 9   9   9   GLU GLU D . n 
D 1 10  PRO 10  10  10  PRO PRO D . n 
D 1 11  GLN 11  11  11  GLN GLN D . n 
D 1 12  MET 12  12  12  MET MET D . n 
D 1 13  VAL 13  13  13  VAL VAL D . n 
D 1 14  LEU 14  14  14  LEU LEU D . n 
D 1 15  SER 15  15  15  SER SER D . n 
D 1 16  PRO 16  16  16  PRO PRO D . n 
D 1 17  LEU 17  17  17  LEU LEU D . n 
D 1 18  THR 18  18  18  THR THR D . n 
D 1 19  SER 19  19  19  SER SER D . n 
D 1 20  ALA 20  20  20  ALA ALA D . n 
D 1 21  ALA 21  21  21  ALA ALA D . n 
D 1 22  ILE 22  22  22  ILE ILE D . n 
D 1 23  PHE 23  23  23  PHE PHE D . n 
D 1 24  LEU 24  24  24  LEU LEU D . n 
D 1 25  VAL 25  25  25  VAL VAL D . n 
D 1 26  VAL 26  26  26  VAL VAL D . n 
D 1 27  THR 27  27  27  THR THR D . n 
D 1 28  ILE 28  28  28  ILE ILE D . n 
D 1 29  ASP 29  29  29  ASP ASP D . n 
D 1 30  SER 30  30  30  SER SER D . n 
D 1 31  GLY 31  31  31  GLY GLY D . n 
D 1 32  GLY 32  32  32  GLY GLY D . n 
D 1 33  GLU 33  33  33  GLU GLU D . n 
D 1 34  ASP 34  34  34  ASP ASP D . n 
D 1 35  THR 35  35  35  THR THR D . n 
D 1 36  VAL 36  36  36  VAL VAL D . n 
D 1 37  ARG 37  37  37  ARG ARG D . n 
D 1 38  ASP 38  38  38  ASP ASP D . n 
D 1 39  LEU 39  39  39  LEU LEU D . n 
D 1 40  LEU 40  40  40  LEU LEU D . n 
D 1 41  SER 41  41  41  SER SER D . n 
D 1 42  ASP 42  42  42  ASP ASP D . n 
D 1 43  VAL 43  43  43  VAL VAL D . n 
D 1 44  ALA 44  44  44  ALA ALA D . n 
D 1 45  SER 45  45  45  SER SER D . n 
D 1 46  LEU 46  46  46  LEU LEU D . n 
D 1 47  GLU 47  47  47  GLU GLU D . n 
D 1 48  ARG 48  48  48  ARG ARG D . n 
D 1 49  ALA 49  49  49  ALA ALA D . n 
D 1 50  VAL 50  50  50  VAL VAL D . n 
D 1 51  GLY 51  51  51  GLY GLY D . n 
D 1 52  PHE 52  52  52  PHE PHE D . n 
D 1 53  ARG 53  53  53  ARG ARG D . n 
D 1 54  ALA 54  54  54  ALA ALA D . n 
D 1 55  GLN 55  55  55  GLN GLN D . n 
D 1 56  PRO 56  56  56  PRO PRO D . n 
D 1 57  ASP 57  57  57  ASP ASP D . n 
D 1 58  GLY 58  58  58  GLY GLY D . n 
D 1 59  ARG 59  59  59  ARG ARG D . n 
D 1 60  LEU 60  60  60  LEU LEU D . n 
D 1 61  SER 61  61  61  SER SER D . n 
D 1 62  CYS 62  62  62  CYS CYS D . n 
D 1 63  VAL 63  63  63  VAL VAL D . n 
D 1 64  THR 64  64  64  THR THR D . n 
D 1 65  GLY 65  65  65  GLY GLY D . n 
D 1 66  ILE 66  66  66  ILE ILE D . n 
D 1 67  GLY 67  67  67  GLY GLY D . n 
D 1 68  SER 68  68  68  SER SER D . n 
D 1 69  GLU 69  69  69  GLU GLU D . n 
D 1 70  ALA 70  70  70  ALA ALA D . n 
D 1 71  TRP 71  71  71  TRP TRP D . n 
D 1 72  ASP 72  72  72  ASP ASP D . n 
D 1 73  ARG 73  73  73  ARG ARG D . n 
D 1 74  LEU 74  74  74  LEU LEU D . n 
D 1 75  PHE 75  75  75  PHE PHE D . n 
D 1 76  SER 76  76  76  SER SER D . n 
D 1 77  GLY 77  77  77  GLY GLY D . n 
D 1 78  ALA 78  78  78  ALA ALA D . n 
D 1 79  ARG 79  79  79  ARG ARG D . n 
D 1 80  PRO 80  80  80  PRO PRO D . n 
D 1 81  ALA 81  81  81  ALA ALA D . n 
D 1 82  GLY 82  82  82  GLY GLY D . n 
D 1 83  LEU 83  83  83  LEU LEU D . n 
D 1 84  HIS 84  84  84  HIS HIS D . n 
D 1 85  PRO 85  85  85  PRO PRO D . n 
D 1 86  PHE 86  86  86  PHE PHE D . n 
D 1 87  ARG 87  87  87  ARG ARG D . n 
D 1 88  GLU 88  88  88  GLU GLU D . n 
D 1 89  LEU 89  89  89  LEU LEU D . n 
D 1 90  ASP 90  90  90  ASP ASP D . n 
D 1 91  GLY 91  91  91  GLY GLY D . n 
D 1 92  PRO 92  92  92  PRO PRO D . n 
D 1 93  VAL 93  93  93  VAL VAL D . n 
D 1 94  HIS 94  94  94  HIS HIS D . n 
D 1 95  ARG 95  95  95  ARG ARG D . n 
D 1 96  ALA 96  96  96  ALA ALA D . n 
D 1 97  VAL 97  97  97  VAL VAL D . n 
D 1 98  ALA 98  98  98  ALA ALA D . n 
D 1 99  THR 99  99  99  THR THR D . n 
D 1 100 PRO 100 100 100 PRO PRO D . n 
D 1 101 GLY 101 101 101 GLY GLY D . n 
D 1 102 ASP 102 102 102 ASP ASP D . n 
D 1 103 LEU 103 103 103 LEU LEU D . n 
D 1 104 LEU 104 104 104 LEU LEU D . n 
D 1 105 PHE 105 105 105 PHE PHE D . n 
D 1 106 HIS 106 106 106 HIS HIS D . n 
D 1 107 ILE 107 107 107 ILE ILE D . n 
D 1 108 ARG 108 108 108 ARG ARG D . n 
D 1 109 ALA 109 109 109 ALA ALA D . n 
D 1 110 SER 110 110 110 SER SER D . n 
D 1 111 ARG 111 111 111 ARG ARG D . n 
D 1 112 LEU 112 112 112 LEU LEU D . n 
D 1 113 ASP 113 113 113 ASP ASP D . n 
D 1 114 LEU 114 114 114 LEU LEU D . n 
D 1 115 CYS 115 115 115 CYS CYS D . n 
D 1 116 PHE 116 116 116 PHE PHE D . n 
D 1 117 ALA 117 117 117 ALA ALA D . n 
D 1 118 LEU 118 118 118 LEU LEU D . n 
D 1 119 ALA 119 119 119 ALA ALA D . n 
D 1 120 THR 120 120 120 THR THR D . n 
D 1 121 GLU 121 121 121 GLU GLU D . n 
D 1 122 ILE 122 122 122 ILE ILE D . n 
D 1 123 MET 123 123 123 MET MET D . n 
D 1 124 GLY 124 124 124 GLY GLY D . n 
D 1 125 ARG 125 125 125 ARG ARG D . n 
D 1 126 LEU 126 126 126 LEU LEU D . n 
D 1 127 ARG 127 127 127 ARG ARG D . n 
D 1 128 GLY 128 128 128 GLY GLY D . n 
D 1 129 ALA 129 129 129 ALA ALA D . n 
D 1 130 VAL 130 130 130 VAL VAL D . n 
D 1 131 THR 131 131 131 THR THR D . n 
D 1 132 PRO 132 132 132 PRO PRO D . n 
D 1 133 GLN 133 133 133 GLN GLN D . n 
D 1 134 ASP 134 134 134 ASP ASP D . n 
D 1 135 GLU 135 135 135 GLU GLU D . n 
D 1 136 VAL 136 136 136 VAL VAL D . n 
D 1 137 HIS 137 137 137 HIS HIS D . n 
D 1 138 GLY 138 138 138 GLY GLY D . n 
D 1 139 PHE 139 139 139 PHE PHE D . n 
D 1 140 LYS 140 140 140 LYS LYS D . n 
D 1 141 TYR 141 141 141 TYR TYR D . n 
D 1 142 PHE 142 142 142 PHE PHE D . n 
D 1 143 ASP 143 143 143 ASP ASP D . n 
D 1 144 GLU 144 144 144 GLU GLU D . n 
D 1 145 ARG 145 145 145 ARG ARG D . n 
D 1 146 ASP 146 146 146 ASP ASP D . n 
D 1 147 MET 147 147 147 MET MET D . n 
D 1 148 LEU 148 148 148 LEU LEU D . n 
D 1 149 GLY 149 149 149 GLY GLY D . n 
D 1 150 PHE 150 150 150 PHE PHE D . n 
D 1 151 VAL 151 151 151 VAL VAL D . n 
D 1 152 ASP 152 152 152 ASP ASP D . n 
D 1 153 GLY 153 153 153 GLY GLY D . n 
D 1 154 THR 154 154 154 THR THR D . n 
D 1 155 GLU 155 155 155 GLU GLU D . n 
D 1 156 ASN 156 156 156 ASN ASN D . n 
D 1 157 PRO 157 157 157 PRO PRO D . n 
D 1 158 THR 158 158 158 THR THR D . n 
D 1 159 GLY 159 159 159 GLY GLY D . n 
D 1 160 ALA 160 160 160 ALA ALA D . n 
D 1 161 ALA 161 161 161 ALA ALA D . n 
D 1 162 ALA 162 162 162 ALA ALA D . n 
D 1 163 ARG 163 163 163 ARG ARG D . n 
D 1 164 ARG 164 164 164 ARG ARG D . n 
D 1 165 ALA 165 165 165 ALA ALA D . n 
D 1 166 VAL 166 166 166 VAL VAL D . n 
D 1 167 LEU 167 167 167 LEU LEU D . n 
D 1 168 VAL 168 168 168 VAL VAL D . n 
D 1 169 GLY 169 169 169 GLY GLY D . n 
D 1 170 ALA 170 170 170 ALA ALA D . n 
D 1 171 GLU 171 171 171 GLU GLU D . n 
D 1 172 ASP 172 172 172 ASP ASP D . n 
D 1 173 PRO 173 173 173 PRO PRO D . n 
D 1 174 ALA 174 174 174 ALA ALA D . n 
D 1 175 PHE 175 175 175 PHE PHE D . n 
D 1 176 ALA 176 176 176 ALA ALA D . n 
D 1 177 GLY 177 177 177 GLY GLY D . n 
D 1 178 GLY 178 178 178 GLY GLY D . n 
D 1 179 SER 179 179 179 SER SER D . n 
D 1 180 TYR 180 180 180 TYR TYR D . n 
D 1 181 ALA 181 181 181 ALA ALA D . n 
D 1 182 VAL 182 182 182 VAL VAL D . n 
D 1 183 VAL 183 183 183 VAL VAL D . n 
D 1 184 GLN 184 184 184 GLN GLN D . n 
D 1 185 LYS 185 185 185 LYS LYS D . n 
D 1 186 TYR 186 186 186 TYR TYR D . n 
D 1 187 LEU 187 187 187 LEU LEU D . n 
D 1 188 HIS 188 188 188 HIS HIS D . n 
D 1 189 ASP 189 189 189 ASP ASP D . n 
D 1 190 ILE 190 190 190 ILE ILE D . n 
D 1 191 ASP 191 191 191 ASP ASP D . n 
D 1 192 ALA 192 192 192 ALA ALA D . n 
D 1 193 TRP 193 193 193 TRP TRP D . n 
D 1 194 GLU 194 194 194 GLU GLU D . n 
D 1 195 GLY 195 195 195 GLY GLY D . n 
D 1 196 LEU 196 196 196 LEU LEU D . n 
D 1 197 SER 197 197 197 SER SER D . n 
D 1 198 VAL 198 198 198 VAL VAL D . n 
D 1 199 GLU 199 199 199 GLU GLU D . n 
D 1 200 ALA 200 200 200 ALA ALA D . n 
D 1 201 GLN 201 201 201 GLN GLN D . n 
D 1 202 GLU 202 202 202 GLU GLU D . n 
D 1 203 ARG 203 203 203 ARG ARG D . n 
D 1 204 VAL 204 204 204 VAL VAL D . n 
D 1 205 ILE 205 205 205 ILE ILE D . n 
D 1 206 GLY 206 206 206 GLY GLY D . n 
D 1 207 ARG 207 207 207 ARG ARG D . n 
D 1 208 ARG 208 208 208 ARG ARG D . n 
D 1 209 LYS 209 209 209 LYS LYS D . n 
D 1 210 MET 210 210 210 MET MET D . n 
D 1 211 THR 211 211 211 THR THR D . n 
D 1 212 ASP 212 212 212 ASP ASP D . n 
D 1 213 VAL 213 213 213 VAL VAL D . n 
D 1 214 GLU 214 214 214 GLU GLU D . n 
D 1 215 LEU 215 215 215 LEU LEU D . n 
D 1 216 SER 216 216 216 SER SER D . n 
D 1 217 ASP 217 217 217 ASP ASP D . n 
D 1 218 ASP 218 218 218 ASP ASP D . n 
D 1 219 VAL 219 219 219 VAL VAL D . n 
D 1 220 LYS 220 220 220 LYS LYS D . n 
D 1 221 PRO 221 221 221 PRO PRO D . n 
D 1 222 ALA 222 222 222 ALA ALA D . n 
D 1 223 ASP 223 223 223 ASP ASP D . n 
D 1 224 SER 224 224 224 SER SER D . n 
D 1 225 HIS 225 225 225 HIS HIS D . n 
D 1 226 VAL 226 226 226 VAL VAL D . n 
D 1 227 ALA 227 227 227 ALA ALA D . n 
D 1 228 LEU 228 228 228 LEU LEU D . n 
D 1 229 THR 229 229 229 THR THR D . n 
D 1 230 SER 230 230 230 SER SER D . n 
D 1 231 VAL 231 231 231 VAL VAL D . n 
D 1 232 THR 232 232 232 THR THR D . n 
D 1 233 GLY 233 233 233 GLY GLY D . n 
D 1 234 PRO 234 234 234 PRO PRO D . n 
D 1 235 ASP 235 235 235 ASP ASP D . n 
D 1 236 GLY 236 236 236 GLY GLY D . n 
D 1 237 SER 237 237 237 SER SER D . n 
D 1 238 ASP 238 238 238 ASP ASP D . n 
D 1 239 LEU 239 239 239 LEU LEU D . n 
D 1 240 GLU 240 240 240 GLU GLU D . n 
D 1 241 ILE 241 241 241 ILE ILE D . n 
D 1 242 LEU 242 242 242 LEU LEU D . n 
D 1 243 ARG 243 243 243 ARG ARG D . n 
D 1 244 ASP 244 244 244 ASP ASP D . n 
D 1 245 ASN 245 245 245 ASN ASN D . n 
D 1 246 MET 246 246 246 MET MET D . n 
D 1 247 PRO 247 247 247 PRO PRO D . n 
D 1 248 PHE 248 248 248 PHE PHE D . n 
D 1 249 GLY 249 249 249 GLY GLY D . n 
D 1 250 SER 250 250 250 SER SER D . n 
D 1 251 VAL 251 251 251 VAL VAL D . n 
D 1 252 GLY 252 252 252 GLY GLY D . n 
D 1 253 ARG 253 253 253 ARG ARG D . n 
D 1 254 GLU 254 254 254 GLU GLU D . n 
D 1 255 GLU 255 255 255 GLU GLU D . n 
D 1 256 PHE 256 256 256 PHE PHE D . n 
D 1 257 GLY 257 257 257 GLY GLY D . n 
D 1 258 THR 258 258 258 THR THR D . n 
D 1 259 TYR 259 259 259 TYR TYR D . n 
D 1 260 PHE 260 260 260 PHE PHE D . n 
D 1 261 ILE 261 261 261 ILE ILE D . n 
D 1 262 GLY 262 262 262 GLY GLY D . n 
D 1 263 TYR 263 263 263 TYR TYR D . n 
D 1 264 ALA 264 264 264 ALA ALA D . n 
D 1 265 ARG 265 265 265 ARG ARG D . n 
D 1 266 THR 266 266 266 THR THR D . n 
D 1 267 PRO 267 267 267 PRO PRO D . n 
D 1 268 GLU 268 268 268 GLU GLU D . n 
D 1 269 VAL 269 269 269 VAL VAL D . n 
D 1 270 THR 270 270 270 THR THR D . n 
D 1 271 GLU 271 271 271 GLU GLU D . n 
D 1 272 THR 272 272 272 THR THR D . n 
D 1 273 MET 273 273 273 MET MET D . n 
D 1 274 LEU 274 274 274 LEU LEU D . n 
D 1 275 GLU 275 275 275 GLU GLU D . n 
D 1 276 ARG 276 276 276 ARG ARG D . n 
D 1 277 MET 277 277 277 MET MET D . n 
D 1 278 PHE 278 278 278 PHE PHE D . n 
D 1 279 LEU 279 279 279 LEU LEU D . n 
D 1 280 GLY 280 280 280 GLY GLY D . n 
D 1 281 THR 281 281 281 THR THR D . n 
D 1 282 ALA 282 282 282 ALA ALA D . n 
D 1 283 SER 283 283 283 SER SER D . n 
D 1 284 ALA 284 284 284 ALA ALA D . n 
D 1 285 PRO 285 285 285 PRO PRO D . n 
D 1 286 HIS 286 286 286 HIS HIS D . n 
D 1 287 ASP 287 287 287 ASP ASP D . n 
D 1 288 ARG 288 288 288 ARG ARG D . n 
D 1 289 ILE 289 289 289 ILE ILE D . n 
D 1 290 LEU 290 290 290 LEU LEU D . n 
D 1 291 ASP 291 291 291 ASP ASP D . n 
D 1 292 PHE 292 292 292 PHE PHE D . n 
D 1 293 SER 293 293 293 SER SER D . n 
D 1 294 THR 294 294 294 THR THR D . n 
D 1 295 ALA 295 295 295 ALA ALA D . n 
D 1 296 VAL 296 296 296 VAL VAL D . n 
D 1 297 THR 297 297 297 THR THR D . n 
D 1 298 GLY 298 298 298 GLY GLY D . n 
D 1 299 SER 299 299 299 SER SER D . n 
D 1 300 LEU 300 300 300 LEU LEU D . n 
D 1 301 PHE 301 301 301 PHE PHE D . n 
D 1 302 PHE 302 302 302 PHE PHE D . n 
D 1 303 THR 303 303 303 THR THR D . n 
D 1 304 PRO 304 304 304 PRO PRO D . n 
D 1 305 ALA 305 305 305 ALA ALA D . n 
D 1 306 ALA 306 306 306 ALA ALA D . n 
D 1 307 ASP 307 307 307 ASP ASP D . n 
D 1 308 PHE 308 308 308 PHE PHE D . n 
D 1 309 LEU 309 309 309 LEU LEU D . n 
D 1 310 GLU 310 310 310 GLU GLU D . n 
D 1 311 ASP 311 311 311 ASP ASP D . n 
D 1 312 LEU 312 312 312 LEU LEU D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   GLY 2   2   ?   ?   ?   E . n 
E 1 3   GLY 3   3   ?   ?   ?   E . n 
E 1 4   GLU 4   4   ?   ?   ?   E . n 
E 1 5   VAL 5   5   ?   ?   ?   E . n 
E 1 6   GLU 6   6   ?   ?   ?   E . n 
E 1 7   GLU 7   7   7   GLU GLU E . n 
E 1 8   PRO 8   8   8   PRO PRO E . n 
E 1 9   GLU 9   9   9   GLU GLU E . n 
E 1 10  PRO 10  10  10  PRO PRO E . n 
E 1 11  GLN 11  11  11  GLN GLN E . n 
E 1 12  MET 12  12  12  MET MET E . n 
E 1 13  VAL 13  13  13  VAL VAL E . n 
E 1 14  LEU 14  14  14  LEU LEU E . n 
E 1 15  SER 15  15  15  SER SER E . n 
E 1 16  PRO 16  16  16  PRO PRO E . n 
E 1 17  LEU 17  17  17  LEU LEU E . n 
E 1 18  THR 18  18  18  THR THR E . n 
E 1 19  SER 19  19  19  SER SER E . n 
E 1 20  ALA 20  20  20  ALA ALA E . n 
E 1 21  ALA 21  21  21  ALA ALA E . n 
E 1 22  ILE 22  22  22  ILE ILE E . n 
E 1 23  PHE 23  23  23  PHE PHE E . n 
E 1 24  LEU 24  24  24  LEU LEU E . n 
E 1 25  VAL 25  25  25  VAL VAL E . n 
E 1 26  VAL 26  26  26  VAL VAL E . n 
E 1 27  THR 27  27  27  THR THR E . n 
E 1 28  ILE 28  28  28  ILE ILE E . n 
E 1 29  ASP 29  29  29  ASP ASP E . n 
E 1 30  SER 30  30  30  SER SER E . n 
E 1 31  GLY 31  31  31  GLY GLY E . n 
E 1 32  GLY 32  32  32  GLY GLY E . n 
E 1 33  GLU 33  33  33  GLU GLU E . n 
E 1 34  ASP 34  34  34  ASP ASP E . n 
E 1 35  THR 35  35  35  THR THR E . n 
E 1 36  VAL 36  36  36  VAL VAL E . n 
E 1 37  ARG 37  37  37  ARG ARG E . n 
E 1 38  ASP 38  38  38  ASP ASP E . n 
E 1 39  LEU 39  39  39  LEU LEU E . n 
E 1 40  LEU 40  40  40  LEU LEU E . n 
E 1 41  SER 41  41  41  SER SER E . n 
E 1 42  ASP 42  42  42  ASP ASP E . n 
E 1 43  VAL 43  43  43  VAL VAL E . n 
E 1 44  ALA 44  44  44  ALA ALA E . n 
E 1 45  SER 45  45  45  SER SER E . n 
E 1 46  LEU 46  46  46  LEU LEU E . n 
E 1 47  GLU 47  47  47  GLU GLU E . n 
E 1 48  ARG 48  48  48  ARG ARG E . n 
E 1 49  ALA 49  49  49  ALA ALA E . n 
E 1 50  VAL 50  50  50  VAL VAL E . n 
E 1 51  GLY 51  51  51  GLY GLY E . n 
E 1 52  PHE 52  52  52  PHE PHE E . n 
E 1 53  ARG 53  53  53  ARG ARG E . n 
E 1 54  ALA 54  54  54  ALA ALA E . n 
E 1 55  GLN 55  55  55  GLN GLN E . n 
E 1 56  PRO 56  56  56  PRO PRO E . n 
E 1 57  ASP 57  57  57  ASP ASP E . n 
E 1 58  GLY 58  58  58  GLY GLY E . n 
E 1 59  ARG 59  59  59  ARG ARG E . n 
E 1 60  LEU 60  60  60  LEU LEU E . n 
E 1 61  SER 61  61  61  SER SER E . n 
E 1 62  CYS 62  62  62  CYS CYS E . n 
E 1 63  VAL 63  63  63  VAL VAL E . n 
E 1 64  THR 64  64  64  THR THR E . n 
E 1 65  GLY 65  65  65  GLY GLY E . n 
E 1 66  ILE 66  66  66  ILE ILE E . n 
E 1 67  GLY 67  67  67  GLY GLY E . n 
E 1 68  SER 68  68  68  SER SER E . n 
E 1 69  GLU 69  69  69  GLU GLU E . n 
E 1 70  ALA 70  70  70  ALA ALA E . n 
E 1 71  TRP 71  71  71  TRP TRP E . n 
E 1 72  ASP 72  72  72  ASP ASP E . n 
E 1 73  ARG 73  73  73  ARG ARG E . n 
E 1 74  LEU 74  74  74  LEU LEU E . n 
E 1 75  PHE 75  75  75  PHE PHE E . n 
E 1 76  SER 76  76  76  SER SER E . n 
E 1 77  GLY 77  77  77  GLY GLY E . n 
E 1 78  ALA 78  78  78  ALA ALA E . n 
E 1 79  ARG 79  79  79  ARG ARG E . n 
E 1 80  PRO 80  80  80  PRO PRO E . n 
E 1 81  ALA 81  81  81  ALA ALA E . n 
E 1 82  GLY 82  82  82  GLY GLY E . n 
E 1 83  LEU 83  83  83  LEU LEU E . n 
E 1 84  HIS 84  84  84  HIS HIS E . n 
E 1 85  PRO 85  85  85  PRO PRO E . n 
E 1 86  PHE 86  86  86  PHE PHE E . n 
E 1 87  ARG 87  87  87  ARG ARG E . n 
E 1 88  GLU 88  88  88  GLU GLU E . n 
E 1 89  LEU 89  89  89  LEU LEU E . n 
E 1 90  ASP 90  90  90  ASP ASP E . n 
E 1 91  GLY 91  91  91  GLY GLY E . n 
E 1 92  PRO 92  92  92  PRO PRO E . n 
E 1 93  VAL 93  93  93  VAL VAL E . n 
E 1 94  HIS 94  94  94  HIS HIS E . n 
E 1 95  ARG 95  95  95  ARG ARG E . n 
E 1 96  ALA 96  96  96  ALA ALA E . n 
E 1 97  VAL 97  97  97  VAL VAL E . n 
E 1 98  ALA 98  98  98  ALA ALA E . n 
E 1 99  THR 99  99  99  THR THR E . n 
E 1 100 PRO 100 100 100 PRO PRO E . n 
E 1 101 GLY 101 101 101 GLY GLY E . n 
E 1 102 ASP 102 102 102 ASP ASP E . n 
E 1 103 LEU 103 103 103 LEU LEU E . n 
E 1 104 LEU 104 104 104 LEU LEU E . n 
E 1 105 PHE 105 105 105 PHE PHE E . n 
E 1 106 HIS 106 106 106 HIS HIS E . n 
E 1 107 ILE 107 107 107 ILE ILE E . n 
E 1 108 ARG 108 108 108 ARG ARG E . n 
E 1 109 ALA 109 109 109 ALA ALA E . n 
E 1 110 SER 110 110 110 SER SER E . n 
E 1 111 ARG 111 111 111 ARG ARG E . n 
E 1 112 LEU 112 112 112 LEU LEU E . n 
E 1 113 ASP 113 113 113 ASP ASP E . n 
E 1 114 LEU 114 114 114 LEU LEU E . n 
E 1 115 CYS 115 115 115 CYS CYS E . n 
E 1 116 PHE 116 116 116 PHE PHE E . n 
E 1 117 ALA 117 117 117 ALA ALA E . n 
E 1 118 LEU 118 118 118 LEU LEU E . n 
E 1 119 ALA 119 119 119 ALA ALA E . n 
E 1 120 THR 120 120 120 THR THR E . n 
E 1 121 GLU 121 121 121 GLU GLU E . n 
E 1 122 ILE 122 122 122 ILE ILE E . n 
E 1 123 MET 123 123 123 MET MET E . n 
E 1 124 GLY 124 124 124 GLY GLY E . n 
E 1 125 ARG 125 125 125 ARG ARG E . n 
E 1 126 LEU 126 126 126 LEU LEU E . n 
E 1 127 ARG 127 127 127 ARG ARG E . n 
E 1 128 GLY 128 128 128 GLY GLY E . n 
E 1 129 ALA 129 129 129 ALA ALA E . n 
E 1 130 VAL 130 130 130 VAL VAL E . n 
E 1 131 THR 131 131 131 THR THR E . n 
E 1 132 PRO 132 132 132 PRO PRO E . n 
E 1 133 GLN 133 133 133 GLN GLN E . n 
E 1 134 ASP 134 134 134 ASP ASP E . n 
E 1 135 GLU 135 135 135 GLU GLU E . n 
E 1 136 VAL 136 136 136 VAL VAL E . n 
E 1 137 HIS 137 137 137 HIS HIS E . n 
E 1 138 GLY 138 138 138 GLY GLY E . n 
E 1 139 PHE 139 139 139 PHE PHE E . n 
E 1 140 LYS 140 140 140 LYS LYS E . n 
E 1 141 TYR 141 141 141 TYR TYR E . n 
E 1 142 PHE 142 142 142 PHE PHE E . n 
E 1 143 ASP 143 143 143 ASP ASP E . n 
E 1 144 GLU 144 144 144 GLU GLU E . n 
E 1 145 ARG 145 145 145 ARG ARG E . n 
E 1 146 ASP 146 146 146 ASP ASP E . n 
E 1 147 MET 147 147 147 MET MET E . n 
E 1 148 LEU 148 148 148 LEU LEU E . n 
E 1 149 GLY 149 149 149 GLY GLY E . n 
E 1 150 PHE 150 150 150 PHE PHE E . n 
E 1 151 VAL 151 151 151 VAL VAL E . n 
E 1 152 ASP 152 152 152 ASP ASP E . n 
E 1 153 GLY 153 153 153 GLY GLY E . n 
E 1 154 THR 154 154 154 THR THR E . n 
E 1 155 GLU 155 155 155 GLU GLU E . n 
E 1 156 ASN 156 156 156 ASN ASN E . n 
E 1 157 PRO 157 157 157 PRO PRO E . n 
E 1 158 THR 158 158 158 THR THR E . n 
E 1 159 GLY 159 159 159 GLY GLY E . n 
E 1 160 ALA 160 160 160 ALA ALA E . n 
E 1 161 ALA 161 161 161 ALA ALA E . n 
E 1 162 ALA 162 162 162 ALA ALA E . n 
E 1 163 ARG 163 163 163 ARG ARG E . n 
E 1 164 ARG 164 164 164 ARG ARG E . n 
E 1 165 ALA 165 165 165 ALA ALA E . n 
E 1 166 VAL 166 166 166 VAL VAL E . n 
E 1 167 LEU 167 167 167 LEU LEU E . n 
E 1 168 VAL 168 168 168 VAL VAL E . n 
E 1 169 GLY 169 169 169 GLY GLY E . n 
E 1 170 ALA 170 170 170 ALA ALA E . n 
E 1 171 GLU 171 171 171 GLU GLU E . n 
E 1 172 ASP 172 172 172 ASP ASP E . n 
E 1 173 PRO 173 173 173 PRO PRO E . n 
E 1 174 ALA 174 174 174 ALA ALA E . n 
E 1 175 PHE 175 175 175 PHE PHE E . n 
E 1 176 ALA 176 176 176 ALA ALA E . n 
E 1 177 GLY 177 177 177 GLY GLY E . n 
E 1 178 GLY 178 178 178 GLY GLY E . n 
E 1 179 SER 179 179 179 SER SER E . n 
E 1 180 TYR 180 180 180 TYR TYR E . n 
E 1 181 ALA 181 181 181 ALA ALA E . n 
E 1 182 VAL 182 182 182 VAL VAL E . n 
E 1 183 VAL 183 183 183 VAL VAL E . n 
E 1 184 GLN 184 184 184 GLN GLN E . n 
E 1 185 LYS 185 185 185 LYS LYS E . n 
E 1 186 TYR 186 186 186 TYR TYR E . n 
E 1 187 LEU 187 187 187 LEU LEU E . n 
E 1 188 HIS 188 188 188 HIS HIS E . n 
E 1 189 ASP 189 189 189 ASP ASP E . n 
E 1 190 ILE 190 190 190 ILE ILE E . n 
E 1 191 ASP 191 191 191 ASP ASP E . n 
E 1 192 ALA 192 192 192 ALA ALA E . n 
E 1 193 TRP 193 193 193 TRP TRP E . n 
E 1 194 GLU 194 194 194 GLU GLU E . n 
E 1 195 GLY 195 195 195 GLY GLY E . n 
E 1 196 LEU 196 196 196 LEU LEU E . n 
E 1 197 SER 197 197 197 SER SER E . n 
E 1 198 VAL 198 198 198 VAL VAL E . n 
E 1 199 GLU 199 199 199 GLU GLU E . n 
E 1 200 ALA 200 200 200 ALA ALA E . n 
E 1 201 GLN 201 201 201 GLN GLN E . n 
E 1 202 GLU 202 202 202 GLU GLU E . n 
E 1 203 ARG 203 203 203 ARG ARG E . n 
E 1 204 VAL 204 204 204 VAL VAL E . n 
E 1 205 ILE 205 205 205 ILE ILE E . n 
E 1 206 GLY 206 206 206 GLY GLY E . n 
E 1 207 ARG 207 207 207 ARG ARG E . n 
E 1 208 ARG 208 208 208 ARG ARG E . n 
E 1 209 LYS 209 209 209 LYS LYS E . n 
E 1 210 MET 210 210 210 MET MET E . n 
E 1 211 THR 211 211 211 THR THR E . n 
E 1 212 ASP 212 212 212 ASP ASP E . n 
E 1 213 VAL 213 213 213 VAL VAL E . n 
E 1 214 GLU 214 214 214 GLU GLU E . n 
E 1 215 LEU 215 215 215 LEU LEU E . n 
E 1 216 SER 216 216 216 SER SER E . n 
E 1 217 ASP 217 217 217 ASP ASP E . n 
E 1 218 ASP 218 218 218 ASP ASP E . n 
E 1 219 VAL 219 219 219 VAL VAL E . n 
E 1 220 LYS 220 220 220 LYS LYS E . n 
E 1 221 PRO 221 221 221 PRO PRO E . n 
E 1 222 ALA 222 222 222 ALA ALA E . n 
E 1 223 ASP 223 223 223 ASP ASP E . n 
E 1 224 SER 224 224 224 SER SER E . n 
E 1 225 HIS 225 225 225 HIS HIS E . n 
E 1 226 VAL 226 226 226 VAL VAL E . n 
E 1 227 ALA 227 227 227 ALA ALA E . n 
E 1 228 LEU 228 228 228 LEU LEU E . n 
E 1 229 THR 229 229 229 THR THR E . n 
E 1 230 SER 230 230 230 SER SER E . n 
E 1 231 VAL 231 231 231 VAL VAL E . n 
E 1 232 THR 232 232 232 THR THR E . n 
E 1 233 GLY 233 233 233 GLY GLY E . n 
E 1 234 PRO 234 234 234 PRO PRO E . n 
E 1 235 ASP 235 235 235 ASP ASP E . n 
E 1 236 GLY 236 236 236 GLY GLY E . n 
E 1 237 SER 237 237 237 SER SER E . n 
E 1 238 ASP 238 238 238 ASP ASP E . n 
E 1 239 LEU 239 239 239 LEU LEU E . n 
E 1 240 GLU 240 240 240 GLU GLU E . n 
E 1 241 ILE 241 241 241 ILE ILE E . n 
E 1 242 LEU 242 242 242 LEU LEU E . n 
E 1 243 ARG 243 243 243 ARG ARG E . n 
E 1 244 ASP 244 244 244 ASP ASP E . n 
E 1 245 ASN 245 245 245 ASN ASN E . n 
E 1 246 MET 246 246 246 MET MET E . n 
E 1 247 PRO 247 247 247 PRO PRO E . n 
E 1 248 PHE 248 248 248 PHE PHE E . n 
E 1 249 GLY 249 249 249 GLY GLY E . n 
E 1 250 SER 250 250 250 SER SER E . n 
E 1 251 VAL 251 251 251 VAL VAL E . n 
E 1 252 GLY 252 252 252 GLY GLY E . n 
E 1 253 ARG 253 253 253 ARG ARG E . n 
E 1 254 GLU 254 254 254 GLU GLU E . n 
E 1 255 GLU 255 255 255 GLU GLU E . n 
E 1 256 PHE 256 256 256 PHE PHE E . n 
E 1 257 GLY 257 257 257 GLY GLY E . n 
E 1 258 THR 258 258 258 THR THR E . n 
E 1 259 TYR 259 259 259 TYR TYR E . n 
E 1 260 PHE 260 260 260 PHE PHE E . n 
E 1 261 ILE 261 261 261 ILE ILE E . n 
E 1 262 GLY 262 262 262 GLY GLY E . n 
E 1 263 TYR 263 263 263 TYR TYR E . n 
E 1 264 ALA 264 264 264 ALA ALA E . n 
E 1 265 ARG 265 265 265 ARG ARG E . n 
E 1 266 THR 266 266 266 THR THR E . n 
E 1 267 PRO 267 267 267 PRO PRO E . n 
E 1 268 GLU 268 268 268 GLU GLU E . n 
E 1 269 VAL 269 269 269 VAL VAL E . n 
E 1 270 THR 270 270 270 THR THR E . n 
E 1 271 GLU 271 271 271 GLU GLU E . n 
E 1 272 THR 272 272 272 THR THR E . n 
E 1 273 MET 273 273 273 MET MET E . n 
E 1 274 LEU 274 274 274 LEU LEU E . n 
E 1 275 GLU 275 275 275 GLU GLU E . n 
E 1 276 ARG 276 276 276 ARG ARG E . n 
E 1 277 MET 277 277 277 MET MET E . n 
E 1 278 PHE 278 278 278 PHE PHE E . n 
E 1 279 LEU 279 279 279 LEU LEU E . n 
E 1 280 GLY 280 280 280 GLY GLY E . n 
E 1 281 THR 281 281 281 THR THR E . n 
E 1 282 ALA 282 282 282 ALA ALA E . n 
E 1 283 SER 283 283 283 SER SER E . n 
E 1 284 ALA 284 284 284 ALA ALA E . n 
E 1 285 PRO 285 285 285 PRO PRO E . n 
E 1 286 HIS 286 286 286 HIS HIS E . n 
E 1 287 ASP 287 287 287 ASP ASP E . n 
E 1 288 ARG 288 288 288 ARG ARG E . n 
E 1 289 ILE 289 289 289 ILE ILE E . n 
E 1 290 LEU 290 290 290 LEU LEU E . n 
E 1 291 ASP 291 291 291 ASP ASP E . n 
E 1 292 PHE 292 292 292 PHE PHE E . n 
E 1 293 SER 293 293 293 SER SER E . n 
E 1 294 THR 294 294 294 THR THR E . n 
E 1 295 ALA 295 295 295 ALA ALA E . n 
E 1 296 VAL 296 296 296 VAL VAL E . n 
E 1 297 THR 297 297 297 THR THR E . n 
E 1 298 GLY 298 298 298 GLY GLY E . n 
E 1 299 SER 299 299 299 SER SER E . n 
E 1 300 LEU 300 300 300 LEU LEU E . n 
E 1 301 PHE 301 301 301 PHE PHE E . n 
E 1 302 PHE 302 302 302 PHE PHE E . n 
E 1 303 THR 303 303 303 THR THR E . n 
E 1 304 PRO 304 304 304 PRO PRO E . n 
E 1 305 ALA 305 305 305 ALA ALA E . n 
E 1 306 ALA 306 306 306 ALA ALA E . n 
E 1 307 ASP 307 307 307 ASP ASP E . n 
E 1 308 PHE 308 308 308 PHE PHE E . n 
E 1 309 LEU 309 309 309 LEU LEU E . n 
E 1 310 GLU 310 310 310 GLU GLU E . n 
E 1 311 ASP 311 311 311 ASP ASP E . n 
E 1 312 LEU 312 312 312 LEU LEU E . n 
F 1 1   MET 1   1   ?   ?   ?   F . n 
F 1 2   GLY 2   2   ?   ?   ?   F . n 
F 1 3   GLY 3   3   ?   ?   ?   F . n 
F 1 4   GLU 4   4   ?   ?   ?   F . n 
F 1 5   VAL 5   5   ?   ?   ?   F . n 
F 1 6   GLU 6   6   ?   ?   ?   F . n 
F 1 7   GLU 7   7   7   GLU GLU F . n 
F 1 8   PRO 8   8   8   PRO PRO F . n 
F 1 9   GLU 9   9   9   GLU GLU F . n 
F 1 10  PRO 10  10  10  PRO PRO F . n 
F 1 11  GLN 11  11  11  GLN GLN F . n 
F 1 12  MET 12  12  12  MET MET F . n 
F 1 13  VAL 13  13  13  VAL VAL F . n 
F 1 14  LEU 14  14  14  LEU LEU F . n 
F 1 15  SER 15  15  15  SER SER F . n 
F 1 16  PRO 16  16  16  PRO PRO F . n 
F 1 17  LEU 17  17  17  LEU LEU F . n 
F 1 18  THR 18  18  18  THR THR F . n 
F 1 19  SER 19  19  19  SER SER F . n 
F 1 20  ALA 20  20  20  ALA ALA F . n 
F 1 21  ALA 21  21  21  ALA ALA F . n 
F 1 22  ILE 22  22  22  ILE ILE F . n 
F 1 23  PHE 23  23  23  PHE PHE F . n 
F 1 24  LEU 24  24  24  LEU LEU F . n 
F 1 25  VAL 25  25  25  VAL VAL F . n 
F 1 26  VAL 26  26  26  VAL VAL F . n 
F 1 27  THR 27  27  27  THR THR F . n 
F 1 28  ILE 28  28  28  ILE ILE F . n 
F 1 29  ASP 29  29  29  ASP ASP F . n 
F 1 30  SER 30  30  30  SER SER F . n 
F 1 31  GLY 31  31  31  GLY GLY F . n 
F 1 32  GLY 32  32  32  GLY GLY F . n 
F 1 33  GLU 33  33  33  GLU GLU F . n 
F 1 34  ASP 34  34  34  ASP ASP F . n 
F 1 35  THR 35  35  35  THR THR F . n 
F 1 36  VAL 36  36  36  VAL VAL F . n 
F 1 37  ARG 37  37  37  ARG ARG F . n 
F 1 38  ASP 38  38  38  ASP ASP F . n 
F 1 39  LEU 39  39  39  LEU LEU F . n 
F 1 40  LEU 40  40  40  LEU LEU F . n 
F 1 41  SER 41  41  41  SER SER F . n 
F 1 42  ASP 42  42  42  ASP ASP F . n 
F 1 43  VAL 43  43  43  VAL VAL F . n 
F 1 44  ALA 44  44  44  ALA ALA F . n 
F 1 45  SER 45  45  45  SER SER F . n 
F 1 46  LEU 46  46  46  LEU LEU F . n 
F 1 47  GLU 47  47  47  GLU GLU F . n 
F 1 48  ARG 48  48  48  ARG ARG F . n 
F 1 49  ALA 49  49  49  ALA ALA F . n 
F 1 50  VAL 50  50  50  VAL VAL F . n 
F 1 51  GLY 51  51  51  GLY GLY F . n 
F 1 52  PHE 52  52  52  PHE PHE F . n 
F 1 53  ARG 53  53  53  ARG ARG F . n 
F 1 54  ALA 54  54  54  ALA ALA F . n 
F 1 55  GLN 55  55  55  GLN GLN F . n 
F 1 56  PRO 56  56  56  PRO PRO F . n 
F 1 57  ASP 57  57  57  ASP ASP F . n 
F 1 58  GLY 58  58  58  GLY GLY F . n 
F 1 59  ARG 59  59  59  ARG ARG F . n 
F 1 60  LEU 60  60  60  LEU LEU F . n 
F 1 61  SER 61  61  61  SER SER F . n 
F 1 62  CYS 62  62  62  CYS CYS F . n 
F 1 63  VAL 63  63  63  VAL VAL F . n 
F 1 64  THR 64  64  64  THR THR F . n 
F 1 65  GLY 65  65  65  GLY GLY F . n 
F 1 66  ILE 66  66  66  ILE ILE F . n 
F 1 67  GLY 67  67  67  GLY GLY F . n 
F 1 68  SER 68  68  68  SER SER F . n 
F 1 69  GLU 69  69  69  GLU GLU F . n 
F 1 70  ALA 70  70  70  ALA ALA F . n 
F 1 71  TRP 71  71  71  TRP TRP F . n 
F 1 72  ASP 72  72  72  ASP ASP F . n 
F 1 73  ARG 73  73  73  ARG ARG F . n 
F 1 74  LEU 74  74  74  LEU LEU F . n 
F 1 75  PHE 75  75  75  PHE PHE F . n 
F 1 76  SER 76  76  76  SER SER F . n 
F 1 77  GLY 77  77  77  GLY GLY F . n 
F 1 78  ALA 78  78  78  ALA ALA F . n 
F 1 79  ARG 79  79  79  ARG ARG F . n 
F 1 80  PRO 80  80  80  PRO PRO F . n 
F 1 81  ALA 81  81  81  ALA ALA F . n 
F 1 82  GLY 82  82  82  GLY GLY F . n 
F 1 83  LEU 83  83  83  LEU LEU F . n 
F 1 84  HIS 84  84  84  HIS HIS F . n 
F 1 85  PRO 85  85  85  PRO PRO F . n 
F 1 86  PHE 86  86  86  PHE PHE F . n 
F 1 87  ARG 87  87  87  ARG ARG F . n 
F 1 88  GLU 88  88  88  GLU GLU F . n 
F 1 89  LEU 89  89  89  LEU LEU F . n 
F 1 90  ASP 90  90  90  ASP ASP F . n 
F 1 91  GLY 91  91  91  GLY GLY F . n 
F 1 92  PRO 92  92  92  PRO PRO F . n 
F 1 93  VAL 93  93  93  VAL VAL F . n 
F 1 94  HIS 94  94  94  HIS HIS F . n 
F 1 95  ARG 95  95  95  ARG ARG F . n 
F 1 96  ALA 96  96  96  ALA ALA F . n 
F 1 97  VAL 97  97  97  VAL VAL F . n 
F 1 98  ALA 98  98  98  ALA ALA F . n 
F 1 99  THR 99  99  99  THR THR F . n 
F 1 100 PRO 100 100 100 PRO PRO F . n 
F 1 101 GLY 101 101 101 GLY GLY F . n 
F 1 102 ASP 102 102 102 ASP ASP F . n 
F 1 103 LEU 103 103 103 LEU LEU F . n 
F 1 104 LEU 104 104 104 LEU LEU F . n 
F 1 105 PHE 105 105 105 PHE PHE F . n 
F 1 106 HIS 106 106 106 HIS HIS F . n 
F 1 107 ILE 107 107 107 ILE ILE F . n 
F 1 108 ARG 108 108 108 ARG ARG F . n 
F 1 109 ALA 109 109 109 ALA ALA F . n 
F 1 110 SER 110 110 110 SER SER F . n 
F 1 111 ARG 111 111 111 ARG ARG F . n 
F 1 112 LEU 112 112 112 LEU LEU F . n 
F 1 113 ASP 113 113 113 ASP ASP F . n 
F 1 114 LEU 114 114 114 LEU LEU F . n 
F 1 115 CYS 115 115 115 CYS CYS F . n 
F 1 116 PHE 116 116 116 PHE PHE F . n 
F 1 117 ALA 117 117 117 ALA ALA F . n 
F 1 118 LEU 118 118 118 LEU LEU F . n 
F 1 119 ALA 119 119 119 ALA ALA F . n 
F 1 120 THR 120 120 120 THR THR F . n 
F 1 121 GLU 121 121 121 GLU GLU F . n 
F 1 122 ILE 122 122 122 ILE ILE F . n 
F 1 123 MET 123 123 123 MET MET F . n 
F 1 124 GLY 124 124 124 GLY GLY F . n 
F 1 125 ARG 125 125 125 ARG ARG F . n 
F 1 126 LEU 126 126 126 LEU LEU F . n 
F 1 127 ARG 127 127 127 ARG ARG F . n 
F 1 128 GLY 128 128 128 GLY GLY F . n 
F 1 129 ALA 129 129 129 ALA ALA F . n 
F 1 130 VAL 130 130 130 VAL VAL F . n 
F 1 131 THR 131 131 131 THR THR F . n 
F 1 132 PRO 132 132 132 PRO PRO F . n 
F 1 133 GLN 133 133 133 GLN GLN F . n 
F 1 134 ASP 134 134 134 ASP ASP F . n 
F 1 135 GLU 135 135 135 GLU GLU F . n 
F 1 136 VAL 136 136 136 VAL VAL F . n 
F 1 137 HIS 137 137 137 HIS HIS F . n 
F 1 138 GLY 138 138 138 GLY GLY F . n 
F 1 139 PHE 139 139 139 PHE PHE F . n 
F 1 140 LYS 140 140 140 LYS LYS F . n 
F 1 141 TYR 141 141 141 TYR TYR F . n 
F 1 142 PHE 142 142 142 PHE PHE F . n 
F 1 143 ASP 143 143 143 ASP ASP F . n 
F 1 144 GLU 144 144 144 GLU GLU F . n 
F 1 145 ARG 145 145 145 ARG ARG F . n 
F 1 146 ASP 146 146 146 ASP ASP F . n 
F 1 147 MET 147 147 147 MET MET F . n 
F 1 148 LEU 148 148 148 LEU LEU F . n 
F 1 149 GLY 149 149 149 GLY GLY F . n 
F 1 150 PHE 150 150 150 PHE PHE F . n 
F 1 151 VAL 151 151 151 VAL VAL F . n 
F 1 152 ASP 152 152 152 ASP ASP F . n 
F 1 153 GLY 153 153 153 GLY GLY F . n 
F 1 154 THR 154 154 154 THR THR F . n 
F 1 155 GLU 155 155 155 GLU GLU F . n 
F 1 156 ASN 156 156 156 ASN ASN F . n 
F 1 157 PRO 157 157 157 PRO PRO F . n 
F 1 158 THR 158 158 158 THR THR F . n 
F 1 159 GLY 159 159 159 GLY GLY F . n 
F 1 160 ALA 160 160 160 ALA ALA F . n 
F 1 161 ALA 161 161 161 ALA ALA F . n 
F 1 162 ALA 162 162 162 ALA ALA F . n 
F 1 163 ARG 163 163 163 ARG ARG F . n 
F 1 164 ARG 164 164 164 ARG ARG F . n 
F 1 165 ALA 165 165 165 ALA ALA F . n 
F 1 166 VAL 166 166 166 VAL VAL F . n 
F 1 167 LEU 167 167 167 LEU LEU F . n 
F 1 168 VAL 168 168 168 VAL VAL F . n 
F 1 169 GLY 169 169 169 GLY GLY F . n 
F 1 170 ALA 170 170 170 ALA ALA F . n 
F 1 171 GLU 171 171 171 GLU GLU F . n 
F 1 172 ASP 172 172 172 ASP ASP F . n 
F 1 173 PRO 173 173 173 PRO PRO F . n 
F 1 174 ALA 174 174 174 ALA ALA F . n 
F 1 175 PHE 175 175 175 PHE PHE F . n 
F 1 176 ALA 176 176 176 ALA ALA F . n 
F 1 177 GLY 177 177 177 GLY GLY F . n 
F 1 178 GLY 178 178 178 GLY GLY F . n 
F 1 179 SER 179 179 179 SER SER F . n 
F 1 180 TYR 180 180 180 TYR TYR F . n 
F 1 181 ALA 181 181 181 ALA ALA F . n 
F 1 182 VAL 182 182 182 VAL VAL F . n 
F 1 183 VAL 183 183 183 VAL VAL F . n 
F 1 184 GLN 184 184 184 GLN GLN F . n 
F 1 185 LYS 185 185 185 LYS LYS F . n 
F 1 186 TYR 186 186 186 TYR TYR F . n 
F 1 187 LEU 187 187 187 LEU LEU F . n 
F 1 188 HIS 188 188 188 HIS HIS F . n 
F 1 189 ASP 189 189 189 ASP ASP F . n 
F 1 190 ILE 190 190 190 ILE ILE F . n 
F 1 191 ASP 191 191 191 ASP ASP F . n 
F 1 192 ALA 192 192 192 ALA ALA F . n 
F 1 193 TRP 193 193 193 TRP TRP F . n 
F 1 194 GLU 194 194 194 GLU GLU F . n 
F 1 195 GLY 195 195 195 GLY GLY F . n 
F 1 196 LEU 196 196 196 LEU LEU F . n 
F 1 197 SER 197 197 197 SER SER F . n 
F 1 198 VAL 198 198 198 VAL VAL F . n 
F 1 199 GLU 199 199 199 GLU GLU F . n 
F 1 200 ALA 200 200 200 ALA ALA F . n 
F 1 201 GLN 201 201 201 GLN GLN F . n 
F 1 202 GLU 202 202 202 GLU GLU F . n 
F 1 203 ARG 203 203 203 ARG ARG F . n 
F 1 204 VAL 204 204 204 VAL VAL F . n 
F 1 205 ILE 205 205 205 ILE ILE F . n 
F 1 206 GLY 206 206 206 GLY GLY F . n 
F 1 207 ARG 207 207 207 ARG ARG F . n 
F 1 208 ARG 208 208 208 ARG ARG F . n 
F 1 209 LYS 209 209 209 LYS LYS F . n 
F 1 210 MET 210 210 210 MET MET F . n 
F 1 211 THR 211 211 211 THR THR F . n 
F 1 212 ASP 212 212 212 ASP ASP F . n 
F 1 213 VAL 213 213 213 VAL VAL F . n 
F 1 214 GLU 214 214 214 GLU GLU F . n 
F 1 215 LEU 215 215 215 LEU LEU F . n 
F 1 216 SER 216 216 216 SER SER F . n 
F 1 217 ASP 217 217 217 ASP ASP F . n 
F 1 218 ASP 218 218 218 ASP ASP F . n 
F 1 219 VAL 219 219 219 VAL VAL F . n 
F 1 220 LYS 220 220 220 LYS LYS F . n 
F 1 221 PRO 221 221 221 PRO PRO F . n 
F 1 222 ALA 222 222 222 ALA ALA F . n 
F 1 223 ASP 223 223 223 ASP ASP F . n 
F 1 224 SER 224 224 224 SER SER F . n 
F 1 225 HIS 225 225 225 HIS HIS F . n 
F 1 226 VAL 226 226 226 VAL VAL F . n 
F 1 227 ALA 227 227 227 ALA ALA F . n 
F 1 228 LEU 228 228 228 LEU LEU F . n 
F 1 229 THR 229 229 229 THR THR F . n 
F 1 230 SER 230 230 230 SER SER F . n 
F 1 231 VAL 231 231 231 VAL VAL F . n 
F 1 232 THR 232 232 232 THR THR F . n 
F 1 233 GLY 233 233 233 GLY GLY F . n 
F 1 234 PRO 234 234 234 PRO PRO F . n 
F 1 235 ASP 235 235 235 ASP ASP F . n 
F 1 236 GLY 236 236 236 GLY GLY F . n 
F 1 237 SER 237 237 237 SER SER F . n 
F 1 238 ASP 238 238 238 ASP ASP F . n 
F 1 239 LEU 239 239 239 LEU LEU F . n 
F 1 240 GLU 240 240 240 GLU GLU F . n 
F 1 241 ILE 241 241 241 ILE ILE F . n 
F 1 242 LEU 242 242 242 LEU LEU F . n 
F 1 243 ARG 243 243 243 ARG ARG F . n 
F 1 244 ASP 244 244 244 ASP ASP F . n 
F 1 245 ASN 245 245 245 ASN ASN F . n 
F 1 246 MET 246 246 246 MET MET F . n 
F 1 247 PRO 247 247 247 PRO PRO F . n 
F 1 248 PHE 248 248 248 PHE PHE F . n 
F 1 249 GLY 249 249 249 GLY GLY F . n 
F 1 250 SER 250 250 250 SER SER F . n 
F 1 251 VAL 251 251 251 VAL VAL F . n 
F 1 252 GLY 252 252 252 GLY GLY F . n 
F 1 253 ARG 253 253 253 ARG ARG F . n 
F 1 254 GLU 254 254 254 GLU GLU F . n 
F 1 255 GLU 255 255 255 GLU GLU F . n 
F 1 256 PHE 256 256 256 PHE PHE F . n 
F 1 257 GLY 257 257 257 GLY GLY F . n 
F 1 258 THR 258 258 258 THR THR F . n 
F 1 259 TYR 259 259 259 TYR TYR F . n 
F 1 260 PHE 260 260 260 PHE PHE F . n 
F 1 261 ILE 261 261 261 ILE ILE F . n 
F 1 262 GLY 262 262 262 GLY GLY F . n 
F 1 263 TYR 263 263 263 TYR TYR F . n 
F 1 264 ALA 264 264 264 ALA ALA F . n 
F 1 265 ARG 265 265 265 ARG ARG F . n 
F 1 266 THR 266 266 266 THR THR F . n 
F 1 267 PRO 267 267 267 PRO PRO F . n 
F 1 268 GLU 268 268 268 GLU GLU F . n 
F 1 269 VAL 269 269 269 VAL VAL F . n 
F 1 270 THR 270 270 270 THR THR F . n 
F 1 271 GLU 271 271 271 GLU GLU F . n 
F 1 272 THR 272 272 272 THR THR F . n 
F 1 273 MET 273 273 273 MET MET F . n 
F 1 274 LEU 274 274 274 LEU LEU F . n 
F 1 275 GLU 275 275 275 GLU GLU F . n 
F 1 276 ARG 276 276 276 ARG ARG F . n 
F 1 277 MET 277 277 277 MET MET F . n 
F 1 278 PHE 278 278 278 PHE PHE F . n 
F 1 279 LEU 279 279 279 LEU LEU F . n 
F 1 280 GLY 280 280 280 GLY GLY F . n 
F 1 281 THR 281 281 281 THR THR F . n 
F 1 282 ALA 282 282 282 ALA ALA F . n 
F 1 283 SER 283 283 283 SER SER F . n 
F 1 284 ALA 284 284 284 ALA ALA F . n 
F 1 285 PRO 285 285 285 PRO PRO F . n 
F 1 286 HIS 286 286 286 HIS HIS F . n 
F 1 287 ASP 287 287 287 ASP ASP F . n 
F 1 288 ARG 288 288 288 ARG ARG F . n 
F 1 289 ILE 289 289 289 ILE ILE F . n 
F 1 290 LEU 290 290 290 LEU LEU F . n 
F 1 291 ASP 291 291 291 ASP ASP F . n 
F 1 292 PHE 292 292 292 PHE PHE F . n 
F 1 293 SER 293 293 293 SER SER F . n 
F 1 294 THR 294 294 294 THR THR F . n 
F 1 295 ALA 295 295 295 ALA ALA F . n 
F 1 296 VAL 296 296 296 VAL VAL F . n 
F 1 297 THR 297 297 297 THR THR F . n 
F 1 298 GLY 298 298 298 GLY GLY F . n 
F 1 299 SER 299 299 299 SER SER F . n 
F 1 300 LEU 300 300 300 LEU LEU F . n 
F 1 301 PHE 301 301 301 PHE PHE F . n 
F 1 302 PHE 302 302 302 PHE PHE F . n 
F 1 303 THR 303 303 303 THR THR F . n 
F 1 304 PRO 304 304 304 PRO PRO F . n 
F 1 305 ALA 305 305 305 ALA ALA F . n 
F 1 306 ALA 306 306 306 ALA ALA F . n 
F 1 307 ASP 307 307 307 ASP ASP F . n 
F 1 308 PHE 308 308 308 PHE PHE F . n 
F 1 309 LEU 309 309 309 LEU LEU F . n 
F 1 310 GLU 310 310 310 GLU GLU F . n 
F 1 311 ASP 311 311 311 ASP ASP F . n 
F 1 312 LEU 312 312 312 LEU LEU F . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 HEM ? ? HEM ? ? 'SUBJECT OF INVESTIGATION' ? 
2 O   ? ? O   ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 HEM 1  401 401 HEM HEM A . 
H 3 MG  1  402 402 MG  MG  A . 
I 4 O   1  403 403 O   O   A . 
J 2 HEM 1  501 401 HEM HEM B . 
K 2 HEM 1  401 401 HEM HEM C . 
L 2 HEM 1  401 401 HEM HEM D . 
M 3 MG  1  402 1   MG  MG  D . 
N 5 PG4 1  403 402 PG4 PG4 D . 
O 4 O   1  404 403 O   O   D . 
P 2 HEM 1  401 401 HEM HEM E . 
Q 2 HEM 1  401 401 HEM HEM F . 
R 6 HOH 1  501 71  HOH HOH A . 
R 6 HOH 2  502 83  HOH HOH A . 
R 6 HOH 3  503 4   HOH HOH A . 
R 6 HOH 4  504 111 HOH HOH A . 
R 6 HOH 5  505 146 HOH HOH A . 
R 6 HOH 6  506 75  HOH HOH A . 
R 6 HOH 7  507 247 HOH HOH A . 
R 6 HOH 8  508 54  HOH HOH A . 
R 6 HOH 9  509 135 HOH HOH A . 
R 6 HOH 10 510 175 HOH HOH A . 
R 6 HOH 11 511 14  HOH HOH A . 
R 6 HOH 12 512 56  HOH HOH A . 
R 6 HOH 13 513 201 HOH HOH A . 
R 6 HOH 14 514 49  HOH HOH A . 
R 6 HOH 15 515 23  HOH HOH A . 
R 6 HOH 16 516 29  HOH HOH A . 
R 6 HOH 17 517 42  HOH HOH A . 
R 6 HOH 18 518 41  HOH HOH A . 
R 6 HOH 19 519 70  HOH HOH A . 
R 6 HOH 20 520 157 HOH HOH A . 
R 6 HOH 21 521 65  HOH HOH A . 
R 6 HOH 22 522 139 HOH HOH A . 
R 6 HOH 23 523 254 HOH HOH A . 
R 6 HOH 24 524 92  HOH HOH A . 
R 6 HOH 25 525 127 HOH HOH A . 
R 6 HOH 26 526 207 HOH HOH A . 
R 6 HOH 27 527 66  HOH HOH A . 
R 6 HOH 28 528 101 HOH HOH A . 
R 6 HOH 29 529 47  HOH HOH A . 
R 6 HOH 30 530 246 HOH HOH A . 
R 6 HOH 31 531 38  HOH HOH A . 
R 6 HOH 32 532 25  HOH HOH A . 
R 6 HOH 33 533 36  HOH HOH A . 
R 6 HOH 34 534 89  HOH HOH A . 
R 6 HOH 35 535 109 HOH HOH A . 
R 6 HOH 36 536 86  HOH HOH A . 
R 6 HOH 37 537 209 HOH HOH A . 
R 6 HOH 38 538 208 HOH HOH A . 
R 6 HOH 39 539 99  HOH HOH A . 
R 6 HOH 40 540 138 HOH HOH A . 
R 6 HOH 41 541 22  HOH HOH A . 
R 6 HOH 42 542 174 HOH HOH A . 
R 6 HOH 43 543 95  HOH HOH A . 
R 6 HOH 44 544 192 HOH HOH A . 
R 6 HOH 45 545 187 HOH HOH A . 
R 6 HOH 46 546 60  HOH HOH A . 
R 6 HOH 47 547 27  HOH HOH A . 
R 6 HOH 48 548 237 HOH HOH A . 
R 6 HOH 49 549 122 HOH HOH A . 
R 6 HOH 50 550 13  HOH HOH A . 
R 6 HOH 51 551 190 HOH HOH A . 
R 6 HOH 52 552 145 HOH HOH A . 
R 6 HOH 53 553 154 HOH HOH A . 
R 6 HOH 54 554 217 HOH HOH A . 
R 6 HOH 55 555 230 HOH HOH A . 
R 6 HOH 56 556 142 HOH HOH A . 
R 6 HOH 57 557 18  HOH HOH A . 
R 6 HOH 58 558 236 HOH HOH A . 
S 6 HOH 1  601 173 HOH HOH B . 
S 6 HOH 2  602 158 HOH HOH B . 
S 6 HOH 3  603 166 HOH HOH B . 
S 6 HOH 4  604 115 HOH HOH B . 
S 6 HOH 5  605 232 HOH HOH B . 
S 6 HOH 6  606 136 HOH HOH B . 
S 6 HOH 7  607 218 HOH HOH B . 
S 6 HOH 8  608 189 HOH HOH B . 
S 6 HOH 9  609 222 HOH HOH B . 
S 6 HOH 10 610 191 HOH HOH B . 
S 6 HOH 11 611 250 HOH HOH B . 
S 6 HOH 12 612 55  HOH HOH B . 
S 6 HOH 13 613 133 HOH HOH B . 
S 6 HOH 14 614 152 HOH HOH B . 
S 6 HOH 15 615 205 HOH HOH B . 
S 6 HOH 16 616 9   HOH HOH B . 
S 6 HOH 17 617 62  HOH HOH B . 
S 6 HOH 18 618 76  HOH HOH B . 
S 6 HOH 19 619 227 HOH HOH B . 
S 6 HOH 20 620 159 HOH HOH B . 
S 6 HOH 21 621 31  HOH HOH B . 
S 6 HOH 22 622 212 HOH HOH B . 
S 6 HOH 23 623 177 HOH HOH B . 
S 6 HOH 24 624 120 HOH HOH B . 
S 6 HOH 25 625 118 HOH HOH B . 
S 6 HOH 26 626 59  HOH HOH B . 
S 6 HOH 27 627 69  HOH HOH B . 
S 6 HOH 28 628 160 HOH HOH B . 
S 6 HOH 29 629 79  HOH HOH B . 
T 6 HOH 1  501 98  HOH HOH C . 
T 6 HOH 2  502 224 HOH HOH C . 
T 6 HOH 3  503 248 HOH HOH C . 
T 6 HOH 4  504 198 HOH HOH C . 
T 6 HOH 5  505 258 HOH HOH C . 
T 6 HOH 6  506 129 HOH HOH C . 
T 6 HOH 7  507 161 HOH HOH C . 
T 6 HOH 8  508 61  HOH HOH C . 
T 6 HOH 9  509 112 HOH HOH C . 
T 6 HOH 10 510 28  HOH HOH C . 
T 6 HOH 11 511 105 HOH HOH C . 
T 6 HOH 12 512 255 HOH HOH C . 
T 6 HOH 13 513 241 HOH HOH C . 
T 6 HOH 14 514 249 HOH HOH C . 
T 6 HOH 15 515 72  HOH HOH C . 
T 6 HOH 16 516 110 HOH HOH C . 
T 6 HOH 17 517 94  HOH HOH C . 
T 6 HOH 18 518 78  HOH HOH C . 
T 6 HOH 19 519 121 HOH HOH C . 
T 6 HOH 20 520 229 HOH HOH C . 
T 6 HOH 21 521 12  HOH HOH C . 
T 6 HOH 22 522 155 HOH HOH C . 
T 6 HOH 23 523 17  HOH HOH C . 
T 6 HOH 24 524 184 HOH HOH C . 
T 6 HOH 25 525 40  HOH HOH C . 
T 6 HOH 26 526 81  HOH HOH C . 
T 6 HOH 27 527 170 HOH HOH C . 
T 6 HOH 28 528 53  HOH HOH C . 
T 6 HOH 29 529 231 HOH HOH C . 
T 6 HOH 30 530 221 HOH HOH C . 
T 6 HOH 31 531 220 HOH HOH C . 
T 6 HOH 32 532 67  HOH HOH C . 
T 6 HOH 33 533 58  HOH HOH C . 
T 6 HOH 34 534 50  HOH HOH C . 
T 6 HOH 35 535 197 HOH HOH C . 
T 6 HOH 36 536 257 HOH HOH C . 
T 6 HOH 37 537 130 HOH HOH C . 
T 6 HOH 38 538 140 HOH HOH C . 
T 6 HOH 39 539 188 HOH HOH C . 
T 6 HOH 40 540 163 HOH HOH C . 
T 6 HOH 41 541 240 HOH HOH C . 
U 6 HOH 1  501 186 HOH HOH D . 
U 6 HOH 2  502 137 HOH HOH D . 
U 6 HOH 3  503 104 HOH HOH D . 
U 6 HOH 4  504 16  HOH HOH D . 
U 6 HOH 5  505 74  HOH HOH D . 
U 6 HOH 6  506 215 HOH HOH D . 
U 6 HOH 7  507 106 HOH HOH D . 
U 6 HOH 8  508 228 HOH HOH D . 
U 6 HOH 9  509 48  HOH HOH D . 
U 6 HOH 10 510 162 HOH HOH D . 
U 6 HOH 11 511 90  HOH HOH D . 
U 6 HOH 12 512 167 HOH HOH D . 
U 6 HOH 13 513 10  HOH HOH D . 
U 6 HOH 14 514 93  HOH HOH D . 
U 6 HOH 15 515 51  HOH HOH D . 
U 6 HOH 16 516 37  HOH HOH D . 
U 6 HOH 17 517 30  HOH HOH D . 
U 6 HOH 18 518 8   HOH HOH D . 
U 6 HOH 19 519 124 HOH HOH D . 
U 6 HOH 20 520 176 HOH HOH D . 
U 6 HOH 21 521 144 HOH HOH D . 
U 6 HOH 22 522 147 HOH HOH D . 
U 6 HOH 23 523 6   HOH HOH D . 
U 6 HOH 24 524 131 HOH HOH D . 
U 6 HOH 25 525 87  HOH HOH D . 
U 6 HOH 26 526 35  HOH HOH D . 
U 6 HOH 27 527 203 HOH HOH D . 
U 6 HOH 28 528 134 HOH HOH D . 
U 6 HOH 29 529 242 HOH HOH D . 
U 6 HOH 30 530 20  HOH HOH D . 
U 6 HOH 31 531 211 HOH HOH D . 
U 6 HOH 32 532 82  HOH HOH D . 
U 6 HOH 33 533 179 HOH HOH D . 
U 6 HOH 34 534 11  HOH HOH D . 
U 6 HOH 35 535 238 HOH HOH D . 
U 6 HOH 36 536 226 HOH HOH D . 
U 6 HOH 37 537 85  HOH HOH D . 
U 6 HOH 38 538 15  HOH HOH D . 
U 6 HOH 39 539 185 HOH HOH D . 
U 6 HOH 40 540 43  HOH HOH D . 
U 6 HOH 41 541 125 HOH HOH D . 
U 6 HOH 42 542 165 HOH HOH D . 
U 6 HOH 43 543 100 HOH HOH D . 
U 6 HOH 44 544 196 HOH HOH D . 
U 6 HOH 45 545 150 HOH HOH D . 
U 6 HOH 46 546 64  HOH HOH D . 
U 6 HOH 47 547 219 HOH HOH D . 
U 6 HOH 48 548 171 HOH HOH D . 
U 6 HOH 49 549 253 HOH HOH D . 
V 6 HOH 1  501 123 HOH HOH E . 
V 6 HOH 2  502 46  HOH HOH E . 
V 6 HOH 3  503 80  HOH HOH E . 
V 6 HOH 4  504 57  HOH HOH E . 
V 6 HOH 5  505 259 HOH HOH E . 
V 6 HOH 6  506 88  HOH HOH E . 
V 6 HOH 7  507 199 HOH HOH E . 
V 6 HOH 8  508 178 HOH HOH E . 
V 6 HOH 9  509 68  HOH HOH E . 
V 6 HOH 10 510 39  HOH HOH E . 
V 6 HOH 11 511 97  HOH HOH E . 
V 6 HOH 12 512 193 HOH HOH E . 
V 6 HOH 13 513 91  HOH HOH E . 
V 6 HOH 14 514 96  HOH HOH E . 
V 6 HOH 15 515 153 HOH HOH E . 
V 6 HOH 16 516 24  HOH HOH E . 
V 6 HOH 17 517 148 HOH HOH E . 
V 6 HOH 18 518 73  HOH HOH E . 
V 6 HOH 19 519 180 HOH HOH E . 
V 6 HOH 20 520 128 HOH HOH E . 
V 6 HOH 21 521 44  HOH HOH E . 
V 6 HOH 22 522 108 HOH HOH E . 
V 6 HOH 23 523 233 HOH HOH E . 
V 6 HOH 24 524 216 HOH HOH E . 
V 6 HOH 25 525 19  HOH HOH E . 
V 6 HOH 26 526 103 HOH HOH E . 
V 6 HOH 27 527 204 HOH HOH E . 
V 6 HOH 28 528 206 HOH HOH E . 
V 6 HOH 29 529 77  HOH HOH E . 
V 6 HOH 30 530 235 HOH HOH E . 
W 6 HOH 1  501 107 HOH HOH F . 
W 6 HOH 2  502 251 HOH HOH F . 
W 6 HOH 3  503 141 HOH HOH F . 
W 6 HOH 4  504 183 HOH HOH F . 
W 6 HOH 5  505 202 HOH HOH F . 
W 6 HOH 6  506 116 HOH HOH F . 
W 6 HOH 7  507 117 HOH HOH F . 
W 6 HOH 8  508 213 HOH HOH F . 
W 6 HOH 9  509 195 HOH HOH F . 
W 6 HOH 10 510 151 HOH HOH F . 
W 6 HOH 11 511 225 HOH HOH F . 
W 6 HOH 12 512 113 HOH HOH F . 
W 6 HOH 13 513 26  HOH HOH F . 
W 6 HOH 14 514 214 HOH HOH F . 
W 6 HOH 15 515 260 HOH HOH F . 
W 6 HOH 16 516 256 HOH HOH F . 
W 6 HOH 17 517 210 HOH HOH F . 
W 6 HOH 18 518 143 HOH HOH F . 
W 6 HOH 19 519 52  HOH HOH F . 
W 6 HOH 20 520 32  HOH HOH F . 
W 6 HOH 21 521 132 HOH HOH F . 
W 6 HOH 22 522 181 HOH HOH F . 
W 6 HOH 23 523 33  HOH HOH F . 
W 6 HOH 24 524 164 HOH HOH F . 
W 6 HOH 25 525 84  HOH HOH F . 
W 6 HOH 26 526 102 HOH HOH F . 
W 6 HOH 27 527 156 HOH HOH F . 
W 6 HOH 28 528 252 HOH HOH F . 
W 6 HOH 29 529 119 HOH HOH F . 
W 6 HOH 30 530 21  HOH HOH F . 
W 6 HOH 31 531 168 HOH HOH F . 
W 6 HOH 32 532 126 HOH HOH F . 
W 6 HOH 33 533 182 HOH HOH F . 
W 6 HOH 34 534 169 HOH HOH F . 
W 6 HOH 35 535 234 HOH HOH F . 
W 6 HOH 36 536 114 HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 9   ? CD  ? A GLU 9   CD  
2   1 Y 1 A GLU 9   ? OE1 ? A GLU 9   OE1 
3   1 Y 1 A GLU 9   ? OE2 ? A GLU 9   OE2 
4   1 Y 1 A ARG 59  ? CZ  ? A ARG 59  CZ  
5   1 Y 1 A ARG 59  ? NH1 ? A ARG 59  NH1 
6   1 Y 1 A ARG 59  ? NH2 ? A ARG 59  NH2 
7   1 Y 1 A LYS 140 ? NZ  ? A LYS 140 NZ  
8   1 Y 1 A ARG 203 ? CZ  ? A ARG 203 CZ  
9   1 Y 1 A ARG 203 ? NH1 ? A ARG 203 NH1 
10  1 Y 1 A ARG 203 ? NH2 ? A ARG 203 NH2 
11  1 Y 1 B GLU 7   ? CG  ? B GLU 7   CG  
12  1 Y 1 B GLU 7   ? CD  ? B GLU 7   CD  
13  1 Y 1 B GLU 7   ? OE1 ? B GLU 7   OE1 
14  1 Y 1 B GLU 7   ? OE2 ? B GLU 7   OE2 
15  1 Y 1 B GLU 9   ? CG  ? B GLU 9   CG  
16  1 Y 1 B GLU 9   ? CD  ? B GLU 9   CD  
17  1 Y 1 B GLU 9   ? OE1 ? B GLU 9   OE1 
18  1 Y 1 B GLU 9   ? OE2 ? B GLU 9   OE2 
19  1 Y 1 B ARG 37  ? CZ  ? B ARG 37  CZ  
20  1 Y 1 B ARG 37  ? NH1 ? B ARG 37  NH1 
21  1 Y 1 B ARG 37  ? NH2 ? B ARG 37  NH2 
22  1 Y 1 B ARG 87  ? NE  ? B ARG 87  NE  
23  1 Y 1 B ARG 87  ? CZ  ? B ARG 87  CZ  
24  1 Y 1 B ARG 87  ? NH1 ? B ARG 87  NH1 
25  1 Y 1 B ARG 87  ? NH2 ? B ARG 87  NH2 
26  1 Y 1 B ARG 95  ? CZ  ? B ARG 95  CZ  
27  1 Y 1 B ARG 95  ? NH1 ? B ARG 95  NH1 
28  1 Y 1 B ARG 95  ? NH2 ? B ARG 95  NH2 
29  1 Y 1 B ARG 163 ? CZ  ? B ARG 163 CZ  
30  1 Y 1 B ARG 163 ? NH1 ? B ARG 163 NH1 
31  1 Y 1 B ARG 163 ? NH2 ? B ARG 163 NH2 
32  1 Y 1 B ARG 164 ? CG  ? B ARG 164 CG  
33  1 Y 1 B ARG 164 ? CD  ? B ARG 164 CD  
34  1 Y 1 B ARG 164 ? NE  ? B ARG 164 NE  
35  1 Y 1 B ARG 164 ? CZ  ? B ARG 164 CZ  
36  1 Y 1 B ARG 164 ? NH1 ? B ARG 164 NH1 
37  1 Y 1 B ARG 164 ? NH2 ? B ARG 164 NH2 
38  1 Y 1 B GLU 268 ? CD  ? B GLU 268 CD  
39  1 Y 1 B GLU 268 ? OE1 ? B GLU 268 OE1 
40  1 Y 1 B GLU 268 ? OE2 ? B GLU 268 OE2 
41  1 Y 1 B GLU 310 ? CD  ? B GLU 310 CD  
42  1 Y 1 B GLU 310 ? OE1 ? B GLU 310 OE1 
43  1 Y 1 B GLU 310 ? OE2 ? B GLU 310 OE2 
44  1 Y 1 C GLU 7   ? CG  ? C GLU 7   CG  
45  1 Y 1 C GLU 7   ? CD  ? C GLU 7   CD  
46  1 Y 1 C GLU 7   ? OE1 ? C GLU 7   OE1 
47  1 Y 1 C GLU 7   ? OE2 ? C GLU 7   OE2 
48  1 Y 1 C GLU 9   ? CD  ? C GLU 9   CD  
49  1 Y 1 C GLU 9   ? OE1 ? C GLU 9   OE1 
50  1 Y 1 C GLU 9   ? OE2 ? C GLU 9   OE2 
51  1 Y 1 C ARG 163 ? NE  ? C ARG 163 NE  
52  1 Y 1 C ARG 163 ? CZ  ? C ARG 163 CZ  
53  1 Y 1 C ARG 163 ? NH1 ? C ARG 163 NH1 
54  1 Y 1 C ARG 163 ? NH2 ? C ARG 163 NH2 
55  1 Y 1 C ASP 218 ? CG  ? C ASP 218 CG  
56  1 Y 1 C ASP 218 ? OD1 ? C ASP 218 OD1 
57  1 Y 1 C ASP 218 ? OD2 ? C ASP 218 OD2 
58  1 Y 1 C SER 237 ? OG  ? C SER 237 OG  
59  1 Y 1 C ARG 253 ? CZ  ? C ARG 253 CZ  
60  1 Y 1 C ARG 253 ? NH1 ? C ARG 253 NH1 
61  1 Y 1 C ARG 253 ? NH2 ? C ARG 253 NH2 
62  1 Y 1 C GLU 268 ? CD  ? C GLU 268 CD  
63  1 Y 1 C GLU 268 ? OE1 ? C GLU 268 OE1 
64  1 Y 1 C GLU 268 ? OE2 ? C GLU 268 OE2 
65  1 Y 1 D GLU 7   ? CG  ? D GLU 7   CG  
66  1 Y 1 D GLU 7   ? CD  ? D GLU 7   CD  
67  1 Y 1 D GLU 7   ? OE1 ? D GLU 7   OE1 
68  1 Y 1 D GLU 7   ? OE2 ? D GLU 7   OE2 
69  1 Y 1 D GLU 9   ? CD  ? D GLU 9   CD  
70  1 Y 1 D GLU 9   ? OE1 ? D GLU 9   OE1 
71  1 Y 1 D GLU 9   ? OE2 ? D GLU 9   OE2 
72  1 Y 1 D LEU 17  ? CG  ? D LEU 17  CG  
73  1 Y 1 D LEU 17  ? CD1 ? D LEU 17  CD1 
74  1 Y 1 D LEU 17  ? CD2 ? D LEU 17  CD2 
75  1 Y 1 D GLN 55  ? CD  ? D GLN 55  CD  
76  1 Y 1 D GLN 55  ? OE1 ? D GLN 55  OE1 
77  1 Y 1 D GLN 55  ? NE2 ? D GLN 55  NE2 
78  1 Y 1 D ASP 57  ? CG  ? D ASP 57  CG  
79  1 Y 1 D ASP 57  ? OD1 ? D ASP 57  OD1 
80  1 Y 1 D ASP 57  ? OD2 ? D ASP 57  OD2 
81  1 Y 1 D ARG 163 ? CZ  ? D ARG 163 CZ  
82  1 Y 1 D ARG 163 ? NH1 ? D ARG 163 NH1 
83  1 Y 1 D ARG 163 ? NH2 ? D ARG 163 NH2 
84  1 Y 1 D ARG 164 ? CD  ? D ARG 164 CD  
85  1 Y 1 D ARG 164 ? NE  ? D ARG 164 NE  
86  1 Y 1 D ARG 164 ? CZ  ? D ARG 164 CZ  
87  1 Y 1 D ARG 164 ? NH1 ? D ARG 164 NH1 
88  1 Y 1 D ARG 164 ? NH2 ? D ARG 164 NH2 
89  1 Y 1 D GLU 268 ? CD  ? D GLU 268 CD  
90  1 Y 1 D GLU 268 ? OE1 ? D GLU 268 OE1 
91  1 Y 1 D GLU 268 ? OE2 ? D GLU 268 OE2 
92  1 Y 1 D GLU 310 ? CG  ? D GLU 310 CG  
93  1 Y 1 D GLU 310 ? CD  ? D GLU 310 CD  
94  1 Y 1 D GLU 310 ? OE1 ? D GLU 310 OE1 
95  1 Y 1 D GLU 310 ? OE2 ? D GLU 310 OE2 
96  1 Y 1 E GLU 7   ? CG  ? E GLU 7   CG  
97  1 Y 1 E GLU 7   ? CD  ? E GLU 7   CD  
98  1 Y 1 E GLU 7   ? OE1 ? E GLU 7   OE1 
99  1 Y 1 E GLU 7   ? OE2 ? E GLU 7   OE2 
100 1 Y 1 E GLU 9   ? CG  ? E GLU 9   CG  
101 1 Y 1 E GLU 9   ? CD  ? E GLU 9   CD  
102 1 Y 1 E GLU 9   ? OE1 ? E GLU 9   OE1 
103 1 Y 1 E GLU 9   ? OE2 ? E GLU 9   OE2 
104 1 Y 1 E ARG 163 ? NE  ? E ARG 163 NE  
105 1 Y 1 E ARG 163 ? CZ  ? E ARG 163 CZ  
106 1 Y 1 E ARG 163 ? NH1 ? E ARG 163 NH1 
107 1 Y 1 E ARG 163 ? NH2 ? E ARG 163 NH2 
108 1 Y 1 E ARG 164 ? CD  ? E ARG 164 CD  
109 1 Y 1 E ARG 164 ? NE  ? E ARG 164 NE  
110 1 Y 1 E ARG 164 ? CZ  ? E ARG 164 CZ  
111 1 Y 1 E ARG 164 ? NH1 ? E ARG 164 NH1 
112 1 Y 1 E ARG 164 ? NH2 ? E ARG 164 NH2 
113 1 Y 1 E ASP 218 ? CG  ? E ASP 218 CG  
114 1 Y 1 E ASP 218 ? OD1 ? E ASP 218 OD1 
115 1 Y 1 E ASP 218 ? OD2 ? E ASP 218 OD2 
116 1 Y 1 E ASP 235 ? CG  ? E ASP 235 CG  
117 1 Y 1 E ASP 235 ? OD1 ? E ASP 235 OD1 
118 1 Y 1 E ASP 235 ? OD2 ? E ASP 235 OD2 
119 1 Y 1 E SER 237 ? OG  ? E SER 237 OG  
120 1 Y 1 E GLU 268 ? CD  ? E GLU 268 CD  
121 1 Y 1 E GLU 268 ? OE1 ? E GLU 268 OE1 
122 1 Y 1 E GLU 268 ? OE2 ? E GLU 268 OE2 
123 1 Y 1 F GLU 7   ? CG  ? F GLU 7   CG  
124 1 Y 1 F GLU 7   ? CD  ? F GLU 7   CD  
125 1 Y 1 F GLU 7   ? OE1 ? F GLU 7   OE1 
126 1 Y 1 F GLU 7   ? OE2 ? F GLU 7   OE2 
127 1 Y 1 F GLU 9   ? CG  ? F GLU 9   CG  
128 1 Y 1 F GLU 9   ? CD  ? F GLU 9   CD  
129 1 Y 1 F GLU 9   ? OE1 ? F GLU 9   OE1 
130 1 Y 1 F GLU 9   ? OE2 ? F GLU 9   OE2 
131 1 Y 1 F ARG 59  ? CZ  ? F ARG 59  CZ  
132 1 Y 1 F ARG 59  ? NH1 ? F ARG 59  NH1 
133 1 Y 1 F ARG 59  ? NH2 ? F ARG 59  NH2 
134 1 Y 1 F SER 76  ? OG  ? F SER 76  OG  
135 1 Y 1 F ARG 95  ? CZ  ? F ARG 95  CZ  
136 1 Y 1 F ARG 95  ? NH1 ? F ARG 95  NH1 
137 1 Y 1 F ARG 95  ? NH2 ? F ARG 95  NH2 
138 1 Y 1 F ARG 127 ? CG  ? F ARG 127 CG  
139 1 Y 1 F ARG 127 ? CD  ? F ARG 127 CD  
140 1 Y 1 F ARG 127 ? NE  ? F ARG 127 NE  
141 1 Y 1 F ARG 127 ? CZ  ? F ARG 127 CZ  
142 1 Y 1 F ARG 127 ? NH1 ? F ARG 127 NH1 
143 1 Y 1 F ARG 127 ? NH2 ? F ARG 127 NH2 
144 1 Y 1 F ARG 163 ? CD  ? F ARG 163 CD  
145 1 Y 1 F ARG 163 ? NE  ? F ARG 163 NE  
146 1 Y 1 F ARG 163 ? CZ  ? F ARG 163 CZ  
147 1 Y 1 F ARG 163 ? NH1 ? F ARG 163 NH1 
148 1 Y 1 F ARG 163 ? NH2 ? F ARG 163 NH2 
149 1 Y 1 F ASP 235 ? CG  ? F ASP 235 CG  
150 1 Y 1 F ASP 235 ? OD1 ? F ASP 235 OD1 
151 1 Y 1 F ASP 235 ? OD2 ? F ASP 235 OD2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EWJ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     86.850 
_cell.length_a_esd                 ? 
_cell.length_b                     121.896 
_cell.length_b_esd                 ? 
_cell.length_c                     199.551 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EWJ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EWJ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.58 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.39 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'6.2 mg/mL of protein in 20 mM NaPi, 150 mM NaCl pH 7 was mixed with 125 mM MgCl2, 125 mM HEPES, 18% PEG 4000 pH 7.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-09-19 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9686 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I24' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9686 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I24 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9EWJ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.92 
_reflns.d_resolution_low                               40.11 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     161825 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                78.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          1.83 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.98 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   0.124 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.92 
_reflns_shell.d_res_low                                     1.97 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             11231 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               12.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.57 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  0.705 
_reflns_shell.percent_possible_all                          99.8 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.02 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            -0.04 
_refine.aniso_B[2][3]                            0.00 
_refine.aniso_B[3][3]                            0.01 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               33.594 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.961 
_refine.correlation_coeff_Fo_to_Fc_free          0.938 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9EWJ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.92 
_refine.ls_d_res_low                             40.11 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     153678 
_refine.ls_number_reflns_R_free                  8044 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.97 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.20980 
_refine.ls_R_factor_R_free                       0.24509 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.20799 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.157 
_refine.pdbx_overall_ESU_R_Free                  0.146 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             9.821 
_refine.overall_SU_ML                            0.232 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.92 
_refine_hist.d_res_low                        40.11 
_refine_hist.number_atoms_solvent             243 
_refine_hist.number_atoms_total               14342 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        13926 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         173 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.016  0.012  14436 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  13219 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 2.570  1.851  19703 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.890  1.753  30418 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.684  5.000  1828  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 15.156 5.000  121   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 15.194 10.000 2145  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.113  0.200  2168  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.011  0.020  17382 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020  3350  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 4.351  3.144  7330  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.351  3.144  7330  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 6.324  5.627  9152  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 6.324  5.627  9153  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.958  3.558  7106  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.958  3.558  7105  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 8.518  6.309  10552 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 9.324  28.50  15230 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 9.323  28.50  15210 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       1.920 
_refine_ls_shell.d_res_low                        1.970 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             558 
_refine_ls_shell.number_reflns_R_work             11231 
_refine_ls_shell.percent_reflns_obs               99.86 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.372 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.388 
# 
_struct.entry_id                     9EWJ 
_struct.title                        'Dye-decolourising peroxidase DtpB (224 kGy)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EWJ 
_struct_keywords.text            'Dye-decolourising peroxidase, heme peroxidase, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 3 ? 
I N N 4 ? 
J N N 2 ? 
K N N 2 ? 
L N N 2 ? 
M N N 3 ? 
N N N 5 ? 
O N N 4 ? 
P N N 2 ? 
Q N N 2 ? 
R N N 6 ? 
S N N 6 ? 
T N N 6 ? 
U N N 6 ? 
V N N 6 ? 
W N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A7U9HFU5_STRLI 
_struct_ref.pdbx_db_accession          A0A7U9HFU5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MGGEVEEPEPQMVLSPLTSAAIFLVVTIDSGGEDTVRDLLSDVASLERAVGFRAQPDGRLSCVTGIGSEAWDRLFSGARP
AGLHPFRELDGPVHRAVATPGDLLFHIRASRLDLCFALATEIMGRLRGAVTPQDEVHGFKYFDERDMLGFVDGTENPTGA
AARRAVLVGAEDPAFAGGSYAVVQKYLHDIDAWEGLSVEAQERVIGRRKMTDVELSDDVKPADSHVALTSVTGPDGSDLE
ILRDNMPFGSVGREEFGTYFIGYARTPEVTETMLERMFLGTASAPHDRILDFSTAVTGSLFFTPAADFLEDL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9EWJ A 1 ? 312 ? A0A7U9HFU5 1 ? 312 ? 1 312 
2 1 9EWJ B 1 ? 312 ? A0A7U9HFU5 1 ? 312 ? 1 312 
3 1 9EWJ C 1 ? 312 ? A0A7U9HFU5 1 ? 312 ? 1 312 
4 1 9EWJ D 1 ? 312 ? A0A7U9HFU5 1 ? 312 ? 1 312 
5 1 9EWJ E 1 ? 312 ? A0A7U9HFU5 1 ? 312 ? 1 312 
6 1 9EWJ F 1 ? 312 ? A0A7U9HFU5 1 ? 312 ? 1 312 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 22840 ? 
1 MORE         -244  ? 
1 'SSA (A^2)'  66350 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'equilibrium centrifugation' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 32  ? SER A 41  ? GLY A 32  SER A 41  1 ? 10 
HELX_P HELX_P2  AA2 ASP A 42  ? ARG A 53  ? ASP A 42  ARG A 53  1 ? 12 
HELX_P HELX_P3  AA3 GLY A 67  ? PHE A 75  ? GLY A 67  PHE A 75  1 ? 9  
HELX_P HELX_P4  AA4 ARG A 111 ? ARG A 127 ? ARG A 111 ARG A 127 1 ? 17 
HELX_P HELX_P5  AA5 THR A 158 ? LEU A 167 ? THR A 158 LEU A 167 1 ? 10 
HELX_P HELX_P6  AA6 ASP A 172 ? ALA A 176 ? ASP A 172 ALA A 176 5 ? 5  
HELX_P HELX_P7  AA7 ASP A 189 ? GLY A 195 ? ASP A 189 GLY A 195 1 ? 7  
HELX_P HELX_P8  AA8 SER A 197 ? GLY A 206 ? SER A 197 GLY A 206 1 ? 10 
HELX_P HELX_P9  AA9 SER A 224 ? THR A 229 ? SER A 224 THR A 229 1 ? 6  
HELX_P HELX_P10 AB1 THR A 266 ? GLY A 280 ? THR A 266 GLY A 280 1 ? 15 
HELX_P HELX_P11 AB2 ASP A 287 ? ASP A 291 ? ASP A 287 ASP A 291 5 ? 5  
HELX_P HELX_P12 AB3 ALA A 305 ? ASP A 311 ? ALA A 305 ASP A 311 1 ? 7  
HELX_P HELX_P13 AB4 GLY B 32  ? ARG B 53  ? GLY B 32  ARG B 53  1 ? 22 
HELX_P HELX_P14 AB5 GLY B 67  ? PHE B 75  ? GLY B 67  PHE B 75  1 ? 9  
HELX_P HELX_P15 AB6 ARG B 111 ? ARG B 127 ? ARG B 111 ARG B 127 1 ? 17 
HELX_P HELX_P16 AB7 THR B 158 ? LEU B 167 ? THR B 158 LEU B 167 1 ? 10 
HELX_P HELX_P17 AB8 ASP B 172 ? ALA B 176 ? ASP B 172 ALA B 176 5 ? 5  
HELX_P HELX_P18 AB9 ASP B 189 ? GLY B 195 ? ASP B 189 GLY B 195 1 ? 7  
HELX_P HELX_P19 AC1 SER B 197 ? GLY B 206 ? SER B 197 GLY B 206 1 ? 10 
HELX_P HELX_P20 AC2 SER B 224 ? SER B 230 ? SER B 224 SER B 230 1 ? 7  
HELX_P HELX_P21 AC3 THR B 266 ? GLY B 280 ? THR B 266 GLY B 280 1 ? 15 
HELX_P HELX_P22 AC4 ASP B 287 ? ASP B 291 ? ASP B 287 ASP B 291 5 ? 5  
HELX_P HELX_P23 AC5 ALA B 305 ? ASP B 311 ? ALA B 305 ASP B 311 1 ? 7  
HELX_P HELX_P24 AC6 GLY C 32  ? PHE C 52  ? GLY C 32  PHE C 52  1 ? 21 
HELX_P HELX_P25 AC7 ARG C 53  ? GLN C 55  ? ARG C 53  GLN C 55  5 ? 3  
HELX_P HELX_P26 AC8 GLY C 67  ? PHE C 75  ? GLY C 67  PHE C 75  1 ? 9  
HELX_P HELX_P27 AC9 ARG C 111 ? ARG C 127 ? ARG C 111 ARG C 127 1 ? 17 
HELX_P HELX_P28 AD1 THR C 158 ? LEU C 167 ? THR C 158 LEU C 167 1 ? 10 
HELX_P HELX_P29 AD2 ASP C 172 ? ALA C 176 ? ASP C 172 ALA C 176 5 ? 5  
HELX_P HELX_P30 AD3 ASP C 189 ? GLY C 195 ? ASP C 189 GLY C 195 1 ? 7  
HELX_P HELX_P31 AD4 SER C 197 ? GLY C 206 ? SER C 197 GLY C 206 1 ? 10 
HELX_P HELX_P32 AD5 SER C 224 ? THR C 229 ? SER C 224 THR C 229 1 ? 6  
HELX_P HELX_P33 AD6 THR C 266 ? GLY C 280 ? THR C 266 GLY C 280 1 ? 15 
HELX_P HELX_P34 AD7 ASP C 287 ? ASP C 291 ? ASP C 287 ASP C 291 5 ? 5  
HELX_P HELX_P35 AD8 ALA C 305 ? ASP C 311 ? ALA C 305 ASP C 311 1 ? 7  
HELX_P HELX_P36 AD9 GLY D 32  ? SER D 41  ? GLY D 32  SER D 41  1 ? 10 
HELX_P HELX_P37 AE1 ASP D 42  ? ARG D 53  ? ASP D 42  ARG D 53  1 ? 12 
HELX_P HELX_P38 AE2 GLY D 67  ? PHE D 75  ? GLY D 67  PHE D 75  1 ? 9  
HELX_P HELX_P39 AE3 ARG D 111 ? ARG D 127 ? ARG D 111 ARG D 127 1 ? 17 
HELX_P HELX_P40 AE4 THR D 158 ? LEU D 167 ? THR D 158 LEU D 167 1 ? 10 
HELX_P HELX_P41 AE5 ASP D 172 ? ALA D 176 ? ASP D 172 ALA D 176 5 ? 5  
HELX_P HELX_P42 AE6 ASP D 189 ? GLY D 195 ? ASP D 189 GLY D 195 1 ? 7  
HELX_P HELX_P43 AE7 SER D 197 ? GLY D 206 ? SER D 197 GLY D 206 1 ? 10 
HELX_P HELX_P44 AE8 SER D 224 ? SER D 230 ? SER D 224 SER D 230 1 ? 7  
HELX_P HELX_P45 AE9 THR D 266 ? GLY D 280 ? THR D 266 GLY D 280 1 ? 15 
HELX_P HELX_P46 AF1 ASP D 287 ? ASP D 291 ? ASP D 287 ASP D 291 5 ? 5  
HELX_P HELX_P47 AF2 ALA D 305 ? ASP D 311 ? ALA D 305 ASP D 311 1 ? 7  
HELX_P HELX_P48 AF3 GLY E 32  ? PHE E 52  ? GLY E 32  PHE E 52  1 ? 21 
HELX_P HELX_P49 AF4 ARG E 53  ? GLN E 55  ? ARG E 53  GLN E 55  5 ? 3  
HELX_P HELX_P50 AF5 GLY E 67  ? PHE E 75  ? GLY E 67  PHE E 75  1 ? 9  
HELX_P HELX_P51 AF6 ARG E 111 ? ARG E 127 ? ARG E 111 ARG E 127 1 ? 17 
HELX_P HELX_P52 AF7 THR E 158 ? LEU E 167 ? THR E 158 LEU E 167 1 ? 10 
HELX_P HELX_P53 AF8 ASP E 172 ? ALA E 176 ? ASP E 172 ALA E 176 5 ? 5  
HELX_P HELX_P54 AF9 ASP E 189 ? GLY E 195 ? ASP E 189 GLY E 195 1 ? 7  
HELX_P HELX_P55 AG1 SER E 197 ? GLY E 206 ? SER E 197 GLY E 206 1 ? 10 
HELX_P HELX_P56 AG2 SER E 224 ? THR E 229 ? SER E 224 THR E 229 1 ? 6  
HELX_P HELX_P57 AG3 THR E 266 ? GLY E 280 ? THR E 266 GLY E 280 1 ? 15 
HELX_P HELX_P58 AG4 ASP E 287 ? ASP E 291 ? ASP E 287 ASP E 291 5 ? 5  
HELX_P HELX_P59 AG5 ALA E 305 ? ASP E 311 ? ALA E 305 ASP E 311 1 ? 7  
HELX_P HELX_P60 AG6 GLY F 32  ? PHE F 52  ? GLY F 32  PHE F 52  1 ? 21 
HELX_P HELX_P61 AG7 ARG F 53  ? GLN F 55  ? ARG F 53  GLN F 55  5 ? 3  
HELX_P HELX_P62 AG8 GLY F 67  ? PHE F 75  ? GLY F 67  PHE F 75  1 ? 9  
HELX_P HELX_P63 AG9 ARG F 111 ? ARG F 127 ? ARG F 111 ARG F 127 1 ? 17 
HELX_P HELX_P64 AH1 THR F 158 ? LEU F 167 ? THR F 158 LEU F 167 1 ? 10 
HELX_P HELX_P65 AH2 ASP F 172 ? ALA F 176 ? ASP F 172 ALA F 176 5 ? 5  
HELX_P HELX_P66 AH3 ASP F 189 ? GLY F 195 ? ASP F 189 GLY F 195 1 ? 7  
HELX_P HELX_P67 AH4 SER F 197 ? GLY F 206 ? SER F 197 GLY F 206 1 ? 10 
HELX_P HELX_P68 AH5 SER F 224 ? THR F 229 ? SER F 224 THR F 229 1 ? 6  
HELX_P HELX_P69 AH6 THR F 266 ? GLY F 280 ? THR F 266 GLY F 280 1 ? 15 
HELX_P HELX_P70 AH7 ASP F 287 ? ASP F 291 ? ASP F 287 ASP F 291 5 ? 5  
HELX_P HELX_P71 AH8 ALA F 305 ? ASP F 311 ? ALA F 305 ASP F 311 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 191 OD2 ? ? ? 1_555 H MG  . MG ? ? A ASP 191 A MG  402 1_555 ? ? ? ? ? ? ? 2.113 ? ? 
metalc2  metalc ? ? A HIS 225 NE2 ? ? ? 1_555 G HEM . FE ? ? A HIS 225 A HEM 401 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
metalc3  metalc ? ? G HEM .   FE  ? ? ? 1_555 I O   . O  ? ? A HEM 401 A O   403 1_555 ? ? ? ? ? ? ? 1.868 ? ? 
metalc4  metalc ? ? H MG  .   MG  ? ? ? 1_555 R HOH . O  ? ? A MG  402 A HOH 501 1_555 ? ? ? ? ? ? ? 2.063 ? ? 
metalc5  metalc ? ? H MG  .   MG  ? ? ? 1_555 R HOH . O  ? ? A MG  402 A HOH 518 1_555 ? ? ? ? ? ? ? 2.197 ? ? 
metalc6  metalc ? ? H MG  .   MG  ? ? ? 1_555 R HOH . O  ? ? A MG  402 A HOH 522 1_555 ? ? ? ? ? ? ? 2.095 ? ? 
metalc7  metalc ? ? H MG  .   MG  ? ? ? 1_555 R HOH . O  ? ? A MG  402 A HOH 548 1_555 ? ? ? ? ? ? ? 2.128 ? ? 
metalc8  metalc ? ? H MG  .   MG  ? ? ? 1_555 U HOH . O  ? ? A MG  402 D HOH 535 4_455 ? ? ? ? ? ? ? 1.815 ? ? 
metalc9  metalc ? ? B HIS 225 NE2 ? ? ? 1_555 J HEM . FE ? ? B HIS 225 B HEM 501 1_555 ? ? ? ? ? ? ? 2.099 ? ? 
metalc10 metalc ? ? C HIS 225 NE2 ? ? ? 1_555 K HEM . FE ? ? C HIS 225 C HEM 401 1_555 ? ? ? ? ? ? ? 2.164 ? ? 
metalc11 metalc ? ? K HEM .   FE  ? ? ? 1_555 T HOH . O  ? ? C HEM 401 C HOH 505 1_555 ? ? ? ? ? ? ? 2.486 ? ? 
metalc12 metalc ? ? T HOH .   O   ? ? ? 4_555 M MG  . MG ? ? C HOH 513 D MG  402 1_555 ? ? ? ? ? ? ? 2.305 ? ? 
metalc13 metalc ? ? T HOH .   O   ? ? ? 4_555 M MG  . MG ? ? C HOH 541 D MG  402 1_555 ? ? ? ? ? ? ? 1.862 ? ? 
metalc14 metalc ? ? D HIS 225 NE2 ? ? ? 1_555 L HEM . FE ? ? D HIS 225 D HEM 401 1_555 ? ? ? ? ? ? ? 2.080 ? ? 
metalc15 metalc ? ? L HEM .   FE  ? ? ? 1_555 O O   . O  ? ? D HEM 401 D O   404 1_555 ? ? ? ? ? ? ? 2.088 ? ? 
metalc16 metalc ? ? M MG  .   MG  ? ? ? 1_555 U HOH . O  ? ? D MG  402 D HOH 519 1_555 ? ? ? ? ? ? ? 2.417 ? ? 
metalc17 metalc ? ? M MG  .   MG  ? ? ? 1_555 U HOH . O  ? ? D MG  402 D HOH 529 1_555 ? ? ? ? ? ? ? 2.222 ? ? 
metalc18 metalc ? ? E HIS 225 NE2 ? ? ? 1_555 P HEM . FE ? ? E HIS 225 E HEM 401 1_555 ? ? ? ? ? ? ? 2.141 ? ? 
metalc19 metalc ? ? P HEM .   FE  ? ? ? 1_555 V HOH . O  ? ? E HEM 401 E HOH 505 1_555 ? ? ? ? ? ? ? 2.300 ? ? 
metalc20 metalc ? ? F HIS 225 NE2 ? ? ? 1_555 Q HEM . FE ? ? F HIS 225 F HEM 401 1_555 ? ? ? ? ? ? ? 2.107 ? ? 
metalc21 metalc ? ? Q HEM .   FE  ? ? ? 1_555 W HOH . O  ? ? F HEM 401 F HOH 515 1_555 ? ? ? ? ? ? ? 2.226 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1   OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 501 ? 1_555 90.3  ? 
2   OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 518 ? 1_555 90.0  ? 
3   O   ? R HOH .   ? A HOH 501 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 518 ? 1_555 91.6  ? 
4   OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 522 ? 1_555 79.5  ? 
5   O   ? R HOH .   ? A HOH 501 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 522 ? 1_555 97.6  ? 
6   O   ? R HOH .   ? A HOH 518 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 522 ? 1_555 166.1 ? 
7   OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 548 ? 1_555 100.6 ? 
8   O   ? R HOH .   ? A HOH 501 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 548 ? 1_555 167.0 ? 
9   O   ? R HOH .   ? A HOH 518 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 548 ? 1_555 81.6  ? 
10  O   ? R HOH .   ? A HOH 522 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? R HOH . ? A HOH 548 ? 1_555 91.3  ? 
11  OD2 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? U HOH . ? D HOH 535 ? 4_455 174.3 ? 
12  O   ? R HOH .   ? A HOH 501 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? U HOH . ? D HOH 535 ? 4_455 84.3  ? 
13  O   ? R HOH .   ? A HOH 518 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? U HOH . ? D HOH 535 ? 4_455 92.0  ? 
14  O   ? R HOH .   ? A HOH 522 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? U HOH . ? D HOH 535 ? 4_455 99.3  ? 
15  O   ? R HOH .   ? A HOH 548 ? 1_555 MG ? H MG  . ? A MG  402 ? 1_555 O  ? U HOH . ? D HOH 535 ? 4_455 84.9  ? 
16  NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NA ? G HEM . ? A HEM 401 ? 1_555 92.3  ? 
17  NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NB ? G HEM . ? A HEM 401 ? 1_555 89.8  ? 
18  NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NB ? G HEM . ? A HEM 401 ? 1_555 87.4  ? 
19  NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NC ? G HEM . ? A HEM 401 ? 1_555 94.6  ? 
20  NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NC ? G HEM . ? A HEM 401 ? 1_555 169.7 ? 
21  NB  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 NC ? G HEM . ? A HEM 401 ? 1_555 85.0  ? 
22  NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 97.2  ? 
23  NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 94.2  ? 
24  NB  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 172.8 ? 
25  NC  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 ND ? G HEM . ? A HEM 401 ? 1_555 92.5  ? 
26  NE2 ? A HIS 225 ? A HIS 225 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? I O   . ? A O   403 ? 1_555 167.5 ? 
27  NA  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? I O   . ? A O   403 ? 1_555 90.0  ? 
28  NB  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? I O   . ? A O   403 ? 1_555 78.1  ? 
29  NC  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? I O   . ? A O   403 ? 1_555 81.7  ? 
30  ND  ? G HEM .   ? A HEM 401 ? 1_555 FE ? G HEM . ? A HEM 401 ? 1_555 O  ? I O   . ? A O   403 ? 1_555 94.9  ? 
31  NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 NA ? J HEM . ? B HEM 501 ? 1_555 90.2  ? 
32  NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 NB ? J HEM . ? B HEM 501 ? 1_555 89.5  ? 
33  NA  ? J HEM .   ? B HEM 501 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 NB ? J HEM . ? B HEM 501 ? 1_555 89.9  ? 
34  NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 NC ? J HEM . ? B HEM 501 ? 1_555 91.8  ? 
35  NA  ? J HEM .   ? B HEM 501 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 NC ? J HEM . ? B HEM 501 ? 1_555 174.8 ? 
36  NB  ? J HEM .   ? B HEM 501 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 NC ? J HEM . ? B HEM 501 ? 1_555 85.3  ? 
37  NE2 ? B HIS 225 ? B HIS 225 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 ND ? J HEM . ? B HEM 501 ? 1_555 93.9  ? 
38  NA  ? J HEM .   ? B HEM 501 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 ND ? J HEM . ? B HEM 501 ? 1_555 87.3  ? 
39  NB  ? J HEM .   ? B HEM 501 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 ND ? J HEM . ? B HEM 501 ? 1_555 175.6 ? 
40  NC  ? J HEM .   ? B HEM 501 ? 1_555 FE ? J HEM . ? B HEM 501 ? 1_555 ND ? J HEM . ? B HEM 501 ? 1_555 97.3  ? 
41  NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 NA ? K HEM . ? C HEM 401 ? 1_555 91.8  ? 
42  NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 NB ? K HEM . ? C HEM 401 ? 1_555 92.4  ? 
43  NA  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 NB ? K HEM . ? C HEM 401 ? 1_555 86.3  ? 
44  NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 NC ? K HEM . ? C HEM 401 ? 1_555 93.6  ? 
45  NA  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 NC ? K HEM . ? C HEM 401 ? 1_555 172.5 ? 
46  NB  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 NC ? K HEM . ? C HEM 401 ? 1_555 88.2  ? 
47  NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 ND ? K HEM . ? C HEM 401 ? 1_555 93.3  ? 
48  NA  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 ND ? K HEM . ? C HEM 401 ? 1_555 92.3  ? 
49  NB  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 ND ? K HEM . ? C HEM 401 ? 1_555 174.1 ? 
50  NC  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 ND ? K HEM . ? C HEM 401 ? 1_555 92.6  ? 
51  NE2 ? C HIS 225 ? C HIS 225 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 O  ? T HOH . ? C HOH 505 ? 1_555 174.6 ? 
52  NA  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 O  ? T HOH . ? C HOH 505 ? 1_555 90.5  ? 
53  NB  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 O  ? T HOH . ? C HOH 505 ? 1_555 82.8  ? 
54  NC  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 O  ? T HOH . ? C HOH 505 ? 1_555 83.7  ? 
55  ND  ? K HEM .   ? C HEM 401 ? 1_555 FE ? K HEM . ? C HEM 401 ? 1_555 O  ? T HOH . ? C HOH 505 ? 1_555 91.5  ? 
56  O   ? T HOH .   ? C HOH 513 ? 4_555 MG ? M MG  . ? D MG  402 ? 1_555 O  ? T HOH . ? C HOH 541 ? 4_555 72.2  ? 
57  O   ? T HOH .   ? C HOH 513 ? 4_555 MG ? M MG  . ? D MG  402 ? 1_555 O  ? U HOH . ? D HOH 519 ? 1_555 146.1 ? 
58  O   ? T HOH .   ? C HOH 541 ? 4_555 MG ? M MG  . ? D MG  402 ? 1_555 O  ? U HOH . ? D HOH 519 ? 1_555 77.8  ? 
59  O   ? T HOH .   ? C HOH 513 ? 4_555 MG ? M MG  . ? D MG  402 ? 1_555 O  ? U HOH . ? D HOH 529 ? 1_555 95.9  ? 
60  O   ? T HOH .   ? C HOH 541 ? 4_555 MG ? M MG  . ? D MG  402 ? 1_555 O  ? U HOH . ? D HOH 529 ? 1_555 129.4 ? 
61  O   ? U HOH .   ? D HOH 519 ? 1_555 MG ? M MG  . ? D MG  402 ? 1_555 O  ? U HOH . ? D HOH 529 ? 1_555 91.1  ? 
62  NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 NA ? L HEM . ? D HEM 401 ? 1_555 90.2  ? 
63  NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 NB ? L HEM . ? D HEM 401 ? 1_555 89.4  ? 
64  NA  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 NB ? L HEM . ? D HEM 401 ? 1_555 88.1  ? 
65  NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 NC ? L HEM . ? D HEM 401 ? 1_555 97.7  ? 
66  NA  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 NC ? L HEM . ? D HEM 401 ? 1_555 171.8 ? 
67  NB  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 NC ? L HEM . ? D HEM 401 ? 1_555 89.9  ? 
68  NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 ND ? L HEM . ? D HEM 401 ? 1_555 95.1  ? 
69  NA  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 ND ? L HEM . ? D HEM 401 ? 1_555 89.2  ? 
70  NB  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 ND ? L HEM . ? D HEM 401 ? 1_555 174.8 ? 
71  NC  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 ND ? L HEM . ? D HEM 401 ? 1_555 92.1  ? 
72  NE2 ? D HIS 225 ? D HIS 225 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 O  ? O O   . ? D O   404 ? 1_555 172.1 ? 
73  NA  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 O  ? O O   . ? D O   404 ? 1_555 85.1  ? 
74  NB  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 O  ? O O   . ? D O   404 ? 1_555 84.1  ? 
75  NC  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 O  ? O O   . ? D O   404 ? 1_555 86.8  ? 
76  ND  ? L HEM .   ? D HEM 401 ? 1_555 FE ? L HEM . ? D HEM 401 ? 1_555 O  ? O O   . ? D O   404 ? 1_555 91.2  ? 
77  NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 NA ? P HEM . ? E HEM 401 ? 1_555 93.4  ? 
78  NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 NB ? P HEM . ? E HEM 401 ? 1_555 93.5  ? 
79  NA  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 NB ? P HEM . ? E HEM 401 ? 1_555 93.8  ? 
80  NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 NC ? P HEM . ? E HEM 401 ? 1_555 93.0  ? 
81  NA  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 NC ? P HEM . ? E HEM 401 ? 1_555 173.4 ? 
82  NB  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 NC ? P HEM . ? E HEM 401 ? 1_555 87.5  ? 
83  NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 ND ? P HEM . ? E HEM 401 ? 1_555 89.1  ? 
84  NA  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 ND ? P HEM . ? E HEM 401 ? 1_555 87.3  ? 
85  NB  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 ND ? P HEM . ? E HEM 401 ? 1_555 177.1 ? 
86  NC  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 ND ? P HEM . ? E HEM 401 ? 1_555 91.1  ? 
87  NE2 ? E HIS 225 ? E HIS 225 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 O  ? V HOH . ? E HOH 505 ? 1_555 176.3 ? 
88  NA  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 O  ? V HOH . ? E HOH 505 ? 1_555 82.9  ? 
89  NB  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 O  ? V HOH . ? E HOH 505 ? 1_555 86.9  ? 
90  NC  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 O  ? V HOH . ? E HOH 505 ? 1_555 90.7  ? 
91  ND  ? P HEM .   ? E HEM 401 ? 1_555 FE ? P HEM . ? E HEM 401 ? 1_555 O  ? V HOH . ? E HOH 505 ? 1_555 90.6  ? 
92  NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 NA ? Q HEM . ? F HEM 401 ? 1_555 93.2  ? 
93  NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 NB ? Q HEM . ? F HEM 401 ? 1_555 90.3  ? 
94  NA  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 NB ? Q HEM . ? F HEM 401 ? 1_555 88.5  ? 
95  NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 NC ? Q HEM . ? F HEM 401 ? 1_555 94.5  ? 
96  NA  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 NC ? Q HEM . ? F HEM 401 ? 1_555 172.2 ? 
97  NB  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 NC ? Q HEM . ? F HEM 401 ? 1_555 90.3  ? 
98  NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 ND ? Q HEM . ? F HEM 401 ? 1_555 92.4  ? 
99  NA  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 ND ? Q HEM . ? F HEM 401 ? 1_555 91.0  ? 
100 NB  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 ND ? Q HEM . ? F HEM 401 ? 1_555 177.4 ? 
101 NC  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 ND ? Q HEM . ? F HEM 401 ? 1_555 89.9  ? 
102 NE2 ? F HIS 225 ? F HIS 225 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 O  ? W HOH . ? F HOH 515 ? 1_555 175.0 ? 
103 NA  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 O  ? W HOH . ? F HOH 515 ? 1_555 88.4  ? 
104 NB  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 O  ? W HOH . ? F HOH 515 ? 1_555 85.1  ? 
105 NC  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 O  ? W HOH . ? F HOH 515 ? 1_555 83.8  ? 
106 ND  ? Q HEM .   ? F HEM 401 ? 1_555 FE ? Q HEM . ? F HEM 401 ? 1_555 O  ? W HOH . ? F HOH 515 ? 1_555 92.3  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 55 A . ? GLN 55 A PRO 56 A ? PRO 56 A 1 -1.04 
2 GLN 55 B . ? GLN 55 B PRO 56 B ? PRO 56 B 1 -2.78 
3 GLN 55 C . ? GLN 55 C PRO 56 C ? PRO 56 C 1 -1.33 
4 GLN 55 D . ? GLN 55 D PRO 56 D ? PRO 56 D 1 -7.20 
5 GLN 55 E . ? GLN 55 E PRO 56 E ? PRO 56 E 1 -5.81 
6 GLN 55 F . ? GLN 55 F PRO 56 F ? PRO 56 F 1 -3.17 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 2 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 2 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
AC1 ? 4 ? 
AC2 ? 2 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
AC5 ? 4 ? 
AC6 ? 2 ? 
AC7 ? 4 ? 
AC8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? anti-parallel 
AC8 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 61  ? ILE A 66  ? SER A 61  ILE A 66  
AA1 2 LEU A 103 ? ALA A 109 ? LEU A 103 ALA A 109 
AA1 3 ALA A 20  ? ILE A 28  ? ALA A 20  ILE A 28  
AA1 4 VAL A 130 ? PHE A 139 ? VAL A 130 PHE A 139 
AA2 1 LEU A 89  ? ASP A 90  ? LEU A 89  ASP A 90  
AA2 2 ARG A 95  ? ALA A 96  ? ARG A 95  ALA A 96  
AA3 1 LEU A 242 ? ARG A 243 ? LEU A 242 ARG A 243 
AA3 2 GLU A 255 ? ALA A 264 ? GLU A 255 ALA A 264 
AA3 3 SER A 179 ? HIS A 188 ? SER A 179 HIS A 188 
AA3 4 SER A 293 ? ALA A 295 ? SER A 293 ALA A 295 
AA4 1 MET A 246 ? SER A 250 ? MET A 246 SER A 250 
AA4 2 GLU A 255 ? ALA A 264 ? GLU A 255 ALA A 264 
AA4 3 SER A 179 ? HIS A 188 ? SER A 179 HIS A 188 
AA4 4 SER A 299 ? THR A 303 ? SER A 299 THR A 303 
AA5 1 VAL A 231 ? THR A 232 ? VAL A 231 THR A 232 
AA5 2 ASP A 238 ? LEU A 239 ? ASP A 238 LEU A 239 
AA6 1 SER B 61  ? ILE B 66  ? SER B 61  ILE B 66  
AA6 2 LEU B 103 ? ALA B 109 ? LEU B 103 ALA B 109 
AA6 3 ALA B 20  ? ILE B 28  ? ALA B 20  ILE B 28  
AA6 4 VAL B 130 ? PHE B 139 ? VAL B 130 PHE B 139 
AA7 1 LEU B 89  ? ASP B 90  ? LEU B 89  ASP B 90  
AA7 2 ARG B 95  ? ALA B 96  ? ARG B 95  ALA B 96  
AA8 1 LEU B 242 ? ARG B 243 ? LEU B 242 ARG B 243 
AA8 2 GLU B 255 ? ALA B 264 ? GLU B 255 ALA B 264 
AA8 3 SER B 179 ? HIS B 188 ? SER B 179 HIS B 188 
AA8 4 SER B 293 ? ALA B 295 ? SER B 293 ALA B 295 
AA9 1 MET B 246 ? SER B 250 ? MET B 246 SER B 250 
AA9 2 GLU B 255 ? ALA B 264 ? GLU B 255 ALA B 264 
AA9 3 SER B 179 ? HIS B 188 ? SER B 179 HIS B 188 
AA9 4 SER B 299 ? THR B 303 ? SER B 299 THR B 303 
AB1 1 VAL B 231 ? THR B 232 ? VAL B 231 THR B 232 
AB1 2 ASP B 238 ? LEU B 239 ? ASP B 238 LEU B 239 
AB2 1 SER C 61  ? ILE C 66  ? SER C 61  ILE C 66  
AB2 2 LEU C 103 ? ALA C 109 ? LEU C 103 ALA C 109 
AB2 3 ALA C 20  ? ILE C 28  ? ALA C 20  ILE C 28  
AB2 4 VAL C 130 ? PHE C 139 ? VAL C 130 PHE C 139 
AB3 1 LEU C 89  ? ASP C 90  ? LEU C 89  ASP C 90  
AB3 2 ARG C 95  ? ALA C 96  ? ARG C 95  ALA C 96  
AB4 1 LEU C 242 ? ARG C 243 ? LEU C 242 ARG C 243 
AB4 2 GLU C 255 ? ALA C 264 ? GLU C 255 ALA C 264 
AB4 3 SER C 179 ? HIS C 188 ? SER C 179 HIS C 188 
AB4 4 SER C 293 ? ALA C 295 ? SER C 293 ALA C 295 
AB5 1 MET C 246 ? SER C 250 ? MET C 246 SER C 250 
AB5 2 GLU C 255 ? ALA C 264 ? GLU C 255 ALA C 264 
AB5 3 SER C 179 ? HIS C 188 ? SER C 179 HIS C 188 
AB5 4 SER C 299 ? THR C 303 ? SER C 299 THR C 303 
AB6 1 SER D 61  ? ILE D 66  ? SER D 61  ILE D 66  
AB6 2 LEU D 103 ? ALA D 109 ? LEU D 103 ALA D 109 
AB6 3 ALA D 20  ? ILE D 28  ? ALA D 20  ILE D 28  
AB6 4 VAL D 130 ? PHE D 139 ? VAL D 130 PHE D 139 
AB7 1 LEU D 89  ? ASP D 90  ? LEU D 89  ASP D 90  
AB7 2 ARG D 95  ? ALA D 96  ? ARG D 95  ALA D 96  
AB8 1 LEU D 242 ? ARG D 243 ? LEU D 242 ARG D 243 
AB8 2 GLU D 255 ? ALA D 264 ? GLU D 255 ALA D 264 
AB8 3 SER D 179 ? HIS D 188 ? SER D 179 HIS D 188 
AB8 4 SER D 293 ? ALA D 295 ? SER D 293 ALA D 295 
AB9 1 MET D 246 ? SER D 250 ? MET D 246 SER D 250 
AB9 2 GLU D 255 ? ALA D 264 ? GLU D 255 ALA D 264 
AB9 3 SER D 179 ? HIS D 188 ? SER D 179 HIS D 188 
AB9 4 SER D 299 ? THR D 303 ? SER D 299 THR D 303 
AC1 1 SER E 61  ? ILE E 66  ? SER E 61  ILE E 66  
AC1 2 LEU E 103 ? ALA E 109 ? LEU E 103 ALA E 109 
AC1 3 ALA E 20  ? ILE E 28  ? ALA E 20  ILE E 28  
AC1 4 VAL E 130 ? PHE E 139 ? VAL E 130 PHE E 139 
AC2 1 LEU E 89  ? ASP E 90  ? LEU E 89  ASP E 90  
AC2 2 ARG E 95  ? ALA E 96  ? ARG E 95  ALA E 96  
AC3 1 LEU E 242 ? ARG E 243 ? LEU E 242 ARG E 243 
AC3 2 GLU E 255 ? ALA E 264 ? GLU E 255 ALA E 264 
AC3 3 SER E 179 ? HIS E 188 ? SER E 179 HIS E 188 
AC3 4 SER E 293 ? ALA E 295 ? SER E 293 ALA E 295 
AC4 1 MET E 246 ? SER E 250 ? MET E 246 SER E 250 
AC4 2 GLU E 255 ? ALA E 264 ? GLU E 255 ALA E 264 
AC4 3 SER E 179 ? HIS E 188 ? SER E 179 HIS E 188 
AC4 4 SER E 299 ? THR E 303 ? SER E 299 THR E 303 
AC5 1 SER F 61  ? ILE F 66  ? SER F 61  ILE F 66  
AC5 2 LEU F 103 ? ALA F 109 ? LEU F 103 ALA F 109 
AC5 3 ALA F 20  ? ILE F 28  ? ALA F 20  ILE F 28  
AC5 4 VAL F 130 ? PHE F 139 ? VAL F 130 PHE F 139 
AC6 1 LEU F 89  ? ASP F 90  ? LEU F 89  ASP F 90  
AC6 2 ARG F 95  ? ALA F 96  ? ARG F 95  ALA F 96  
AC7 1 LEU F 242 ? ARG F 243 ? LEU F 242 ARG F 243 
AC7 2 GLU F 255 ? ALA F 264 ? GLU F 255 ALA F 264 
AC7 3 SER F 179 ? HIS F 188 ? SER F 179 HIS F 188 
AC7 4 SER F 293 ? ALA F 295 ? SER F 293 ALA F 295 
AC8 1 MET F 246 ? SER F 250 ? MET F 246 SER F 250 
AC8 2 GLU F 255 ? ALA F 264 ? GLU F 255 ALA F 264 
AC8 3 SER F 179 ? HIS F 188 ? SER F 179 HIS F 188 
AC8 4 SER F 299 ? THR F 303 ? SER F 299 THR F 303 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 61  ? N SER A 61  O ARG A 108 ? O ARG A 108 
AA1 2 3 O ILE A 107 ? O ILE A 107 N ILE A 22  ? N ILE A 22  
AA1 3 4 N VAL A 25  ? N VAL A 25  O GLN A 133 ? O GLN A 133 
AA2 1 2 N LEU A 89  ? N LEU A 89  O ALA A 96  ? O ALA A 96  
AA3 1 2 N LEU A 242 ? N LEU A 242 O TYR A 263 ? O TYR A 263 
AA3 2 3 O PHE A 256 ? O PHE A 256 N HIS A 188 ? N HIS A 188 
AA3 3 4 N LEU A 187 ? N LEU A 187 O THR A 294 ? O THR A 294 
AA4 1 2 N MET A 246 ? N MET A 246 O TYR A 259 ? O TYR A 259 
AA4 2 3 O PHE A 256 ? O PHE A 256 N HIS A 188 ? N HIS A 188 
AA4 3 4 N SER A 179 ? N SER A 179 O THR A 303 ? O THR A 303 
AA5 1 2 N VAL A 231 ? N VAL A 231 O LEU A 239 ? O LEU A 239 
AA6 1 2 N VAL B 63  ? N VAL B 63  O HIS B 106 ? O HIS B 106 
AA6 2 3 O ILE B 107 ? O ILE B 107 N ILE B 22  ? N ILE B 22  
AA6 3 4 N ALA B 21  ? N ALA B 21  O GLY B 138 ? O GLY B 138 
AA7 1 2 N LEU B 89  ? N LEU B 89  O ALA B 96  ? O ALA B 96  
AA8 1 2 N LEU B 242 ? N LEU B 242 O TYR B 263 ? O TYR B 263 
AA8 2 3 O PHE B 256 ? O PHE B 256 N HIS B 188 ? N HIS B 188 
AA8 3 4 N LEU B 187 ? N LEU B 187 O THR B 294 ? O THR B 294 
AA9 1 2 N MET B 246 ? N MET B 246 O TYR B 259 ? O TYR B 259 
AA9 2 3 O PHE B 256 ? O PHE B 256 N HIS B 188 ? N HIS B 188 
AA9 3 4 N SER B 179 ? N SER B 179 O THR B 303 ? O THR B 303 
AB1 1 2 N VAL B 231 ? N VAL B 231 O LEU B 239 ? O LEU B 239 
AB2 1 2 N VAL C 63  ? N VAL C 63  O HIS C 106 ? O HIS C 106 
AB2 2 3 O ILE C 107 ? O ILE C 107 N ILE C 22  ? N ILE C 22  
AB2 3 4 N VAL C 25  ? N VAL C 25  O GLN C 133 ? O GLN C 133 
AB3 1 2 N LEU C 89  ? N LEU C 89  O ALA C 96  ? O ALA C 96  
AB4 1 2 N LEU C 242 ? N LEU C 242 O TYR C 263 ? O TYR C 263 
AB4 2 3 O PHE C 256 ? O PHE C 256 N HIS C 188 ? N HIS C 188 
AB4 3 4 N LEU C 187 ? N LEU C 187 O THR C 294 ? O THR C 294 
AB5 1 2 N PHE C 248 ? N PHE C 248 O GLY C 257 ? O GLY C 257 
AB5 2 3 O PHE C 256 ? O PHE C 256 N HIS C 188 ? N HIS C 188 
AB5 3 4 N ALA C 181 ? N ALA C 181 O PHE C 301 ? O PHE C 301 
AB6 1 2 N VAL D 63  ? N VAL D 63  O HIS D 106 ? O HIS D 106 
AB6 2 3 O ILE D 107 ? O ILE D 107 N ILE D 22  ? N ILE D 22  
AB6 3 4 N VAL D 25  ? N VAL D 25  O GLN D 133 ? O GLN D 133 
AB7 1 2 N LEU D 89  ? N LEU D 89  O ALA D 96  ? O ALA D 96  
AB8 1 2 N LEU D 242 ? N LEU D 242 O TYR D 263 ? O TYR D 263 
AB8 2 3 O PHE D 256 ? O PHE D 256 N HIS D 188 ? N HIS D 188 
AB8 3 4 N LEU D 187 ? N LEU D 187 O THR D 294 ? O THR D 294 
AB9 1 2 N MET D 246 ? N MET D 246 O TYR D 259 ? O TYR D 259 
AB9 2 3 O PHE D 256 ? O PHE D 256 N HIS D 188 ? N HIS D 188 
AB9 3 4 N SER D 179 ? N SER D 179 O THR D 303 ? O THR D 303 
AC1 1 2 N VAL E 63  ? N VAL E 63  O HIS E 106 ? O HIS E 106 
AC1 2 3 O ILE E 107 ? O ILE E 107 N ILE E 22  ? N ILE E 22  
AC1 3 4 N VAL E 25  ? N VAL E 25  O GLN E 133 ? O GLN E 133 
AC2 1 2 N LEU E 89  ? N LEU E 89  O ALA E 96  ? O ALA E 96  
AC3 1 2 N LEU E 242 ? N LEU E 242 O TYR E 263 ? O TYR E 263 
AC3 2 3 O PHE E 256 ? O PHE E 256 N HIS E 188 ? N HIS E 188 
AC3 3 4 N LEU E 187 ? N LEU E 187 O THR E 294 ? O THR E 294 
AC4 1 2 N MET E 246 ? N MET E 246 O TYR E 259 ? O TYR E 259 
AC4 2 3 O PHE E 256 ? O PHE E 256 N HIS E 188 ? N HIS E 188 
AC4 3 4 N ALA E 181 ? N ALA E 181 O PHE E 301 ? O PHE E 301 
AC5 1 2 N VAL F 63  ? N VAL F 63  O HIS F 106 ? O HIS F 106 
AC5 2 3 O ILE F 107 ? O ILE F 107 N ILE F 22  ? N ILE F 22  
AC5 3 4 N VAL F 25  ? N VAL F 25  O GLN F 133 ? O GLN F 133 
AC6 1 2 N LEU F 89  ? N LEU F 89  O ALA F 96  ? O ALA F 96  
AC7 1 2 N LEU F 242 ? N LEU F 242 O TYR F 263 ? O TYR F 263 
AC7 2 3 O PHE F 256 ? O PHE F 256 N HIS F 188 ? N HIS F 188 
AC7 3 4 N LEU F 187 ? N LEU F 187 O THR F 294 ? O THR F 294 
AC8 1 2 N PHE F 248 ? N PHE F 248 O GLY F 257 ? O GLY F 257 
AC8 2 3 O PHE F 256 ? O PHE F 256 N HIS F 188 ? N HIS F 188 
AC8 3 4 N ALA F 181 ? N ALA F 181 O PHE F 301 ? O PHE F 301 
# 
_pdbx_entry_details.entry_id                   9EWJ 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CD A GLU 47  ? ? OE1 A GLU 47  ? ? 1.183 1.252 -0.069 0.011 N 
2 1 CD A GLU 47  ? ? OE2 A GLU 47  ? ? 1.183 1.252 -0.069 0.011 N 
3 1 CD A GLU 199 ? ? OE1 A GLU 199 ? ? 1.321 1.252 0.069  0.011 N 
4 1 CD C GLU 199 ? ? OE1 C GLU 199 ? ? 1.354 1.252 0.102  0.011 N 
5 1 CD C GLU 199 ? ? OE2 C GLU 199 ? ? 1.352 1.252 0.100  0.011 N 
6 1 CD D GLU 199 ? ? OE2 D GLU 199 ? ? 1.347 1.252 0.095  0.011 N 
7 1 CD D GLU 214 ? ? OE1 D GLU 214 ? ? 1.320 1.252 0.068  0.011 N 
8 1 CD E GLU 199 ? ? OE1 E GLU 199 ? ? 1.334 1.252 0.082  0.011 N 
9 1 NE F ARG 243 ? ? CZ  F ARG 243 ? ? 1.406 1.326 0.080  0.013 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE  A ARG 37  ? ? CZ A ARG 37  ? ? NH2 A ARG 37  ? ? 124.32 120.30 4.02   0.50 N 
2  1 OE1 A GLU 47  ? ? CD A GLU 47  ? ? OE2 A GLU 47  ? ? 115.99 123.30 -7.31  1.20 N 
3  1 NE  A ARG 73  ? ? CZ A ARG 73  ? ? NH1 A ARG 73  ? ? 117.14 120.30 -3.16  0.50 N 
4  1 NE  A ARG 79  ? ? CZ A ARG 79  ? ? NH2 A ARG 79  ? ? 117.08 120.30 -3.22  0.50 N 
5  1 CG  A ARG 87  ? ? CD A ARG 87  ? ? NE  A ARG 87  ? ? 98.87  111.80 -12.93 2.10 N 
6  1 NE  A ARG 125 ? ? CZ A ARG 125 ? ? NH2 A ARG 125 ? ? 125.26 120.30 4.96   0.50 N 
7  1 CA  A ARG 127 ? ? CB A ARG 127 ? ? CG  A ARG 127 ? ? 127.99 113.40 14.59  2.20 N 
8  1 N   A PHE 142 ? ? CA A PHE 142 ? ? CB  A PHE 142 ? ? 122.32 110.60 11.72  1.80 N 
9  1 NE  A ARG 145 ? ? CZ A ARG 145 ? ? NH2 A ARG 145 ? ? 115.81 120.30 -4.49  0.50 N 
10 1 N   A MET 210 ? ? CA A MET 210 ? ? CB  A MET 210 ? ? 121.57 110.60 10.97  1.80 N 
11 1 CB  A MET 210 ? ? CG A MET 210 ? ? SD  A MET 210 ? ? 136.54 112.40 24.14  3.00 N 
12 1 CA  A THR 232 ? ? CB A THR 232 ? ? OG1 A THR 232 ? ? 88.18  109.00 -20.82 2.10 N 
13 1 NE  A ARG 253 ? ? CZ A ARG 253 ? ? NH2 A ARG 253 ? ? 125.11 120.30 4.81   0.50 N 
14 1 CB  A ARG 265 ? ? CG A ARG 265 ? ? CD  A ARG 265 ? ? 128.93 111.60 17.33  2.60 N 
15 1 NE  A ARG 265 ? ? CZ A ARG 265 ? ? NH2 A ARG 265 ? ? 123.40 120.30 3.10   0.50 N 
16 1 CB  A LEU 309 ? ? CG A LEU 309 ? ? CD1 A LEU 309 ? ? 100.34 111.00 -10.66 1.70 N 
17 1 CB  B GLU 7   ? ? CA B GLU 7   ? ? C   B GLU 7   ? ? 126.75 110.40 16.35  2.00 N 
18 1 N   B PRO 8   ? ? CA B PRO 8   ? ? CB  B PRO 8   ? ? 95.54  103.30 -7.76  1.20 N 
19 1 CG  B MET 12  ? ? SD B MET 12  ? ? CE  B MET 12  ? ? 112.84 100.20 12.64  1.60 N 
20 1 NE  B ARG 48  ? ? CZ B ARG 48  ? ? NH1 B ARG 48  ? ? 124.36 120.30 4.06   0.50 N 
21 1 CB  B ASP 113 ? ? CG B ASP 113 ? ? OD1 B ASP 113 ? ? 111.85 118.30 -6.45  0.90 N 
22 1 NE  B ARG 207 ? ? CZ B ARG 207 ? ? NH1 B ARG 207 ? ? 116.61 120.30 -3.69  0.50 N 
23 1 CA  B MET 210 ? ? CB B MET 210 ? ? CG  B MET 210 ? ? 102.40 113.30 -10.90 1.70 N 
24 1 CA  B THR 232 ? ? CB B THR 232 ? ? OG1 B THR 232 ? ? 90.82  109.00 -18.18 2.10 N 
25 1 CB  C GLU 7   ? ? CA C GLU 7   ? ? C   C GLU 7   ? ? 126.58 110.40 16.18  2.00 N 
26 1 CG  C MET 12  ? ? SD C MET 12  ? ? CE  C MET 12  ? ? 87.08  100.20 -13.12 1.60 N 
27 1 CB  C LEU 24  ? ? CG C LEU 24  ? ? CD2 C LEU 24  ? ? 100.51 111.00 -10.49 1.70 N 
28 1 CG1 C VAL 43  ? ? CB C VAL 43  ? ? CG2 C VAL 43  ? ? 100.34 110.90 -10.56 1.60 N 
29 1 NE  C ARG 53  ? ? CZ C ARG 53  ? ? NH2 C ARG 53  ? ? 123.68 120.30 3.38   0.50 N 
30 1 CB  C ASP 57  ? ? CA C ASP 57  ? ? C   C ASP 57  ? ? 97.87  110.40 -12.53 2.00 N 
31 1 N   C ARG 95  ? ? CA C ARG 95  ? ? CB  C ARG 95  ? ? 99.28  110.60 -11.32 1.80 N 
32 1 CB  C ARG 127 ? ? CG C ARG 127 ? ? CD  C ARG 127 ? ? 88.67  111.60 -22.93 2.60 N 
33 1 NE  C ARG 127 ? ? CZ C ARG 127 ? ? NH1 C ARG 127 ? ? 123.82 120.30 3.52   0.50 N 
34 1 NE  C ARG 127 ? ? CZ C ARG 127 ? ? NH2 C ARG 127 ? ? 116.83 120.30 -3.47  0.50 N 
35 1 NE  C ARG 145 ? ? CZ C ARG 145 ? ? NH2 C ARG 145 ? ? 117.29 120.30 -3.01  0.50 N 
36 1 CA  C ARG 163 ? ? CB C ARG 163 ? ? CG  C ARG 163 ? ? 130.51 113.40 17.11  2.20 N 
37 1 NE  C ARG 207 ? ? CZ C ARG 207 ? ? NH2 C ARG 207 ? ? 117.17 120.30 -3.13  0.50 N 
38 1 CA  C THR 232 ? ? CB C THR 232 ? ? OG1 C THR 232 ? ? 95.74  109.00 -13.26 2.10 N 
39 1 NE  C ARG 265 ? ? CZ C ARG 265 ? ? NH1 C ARG 265 ? ? 123.55 120.30 3.25   0.50 N 
40 1 CB  D GLU 7   ? ? CA D GLU 7   ? ? C   D GLU 7   ? ? 123.63 110.40 13.23  2.00 N 
41 1 CD  D ARG 53  ? ? NE D ARG 53  ? ? CZ  D ARG 53  ? ? 115.09 123.60 -8.51  1.40 N 
42 1 NE  D ARG 53  ? ? CZ D ARG 53  ? ? NH1 D ARG 53  ? ? 123.39 120.30 3.09   0.50 N 
43 1 CB  D ASP 57  ? ? CA D ASP 57  ? ? C   D ASP 57  ? ? 123.75 110.40 13.35  2.00 N 
44 1 NE  D ARG 79  ? ? CZ D ARG 79  ? ? NH1 D ARG 79  ? ? 123.41 120.30 3.11   0.50 N 
45 1 CG  D ARG 87  ? ? CD D ARG 87  ? ? NE  D ARG 87  ? ? 94.39  111.80 -17.41 2.10 N 
46 1 N   D ARG 95  ? ? CA D ARG 95  ? ? CB  D ARG 95  ? ? 96.18  110.60 -14.42 1.80 N 
47 1 CG  D ARG 95  ? ? CD D ARG 95  ? ? NE  D ARG 95  ? ? 97.74  111.80 -14.06 2.10 N 
48 1 NE  D ARG 108 ? ? CZ D ARG 108 ? ? NH2 D ARG 108 ? ? 123.44 120.30 3.14   0.50 N 
49 1 CD  D ARG 111 ? ? NE D ARG 111 ? ? CZ  D ARG 111 ? ? 136.28 123.60 12.68  1.40 N 
50 1 NE  D ARG 111 ? ? CZ D ARG 111 ? ? NH2 D ARG 111 ? ? 123.94 120.30 3.64   0.50 N 
51 1 CB  D ASP 113 ? ? CG D ASP 113 ? ? OD1 D ASP 113 ? ? 111.39 118.30 -6.91  0.90 N 
52 1 NE  D ARG 125 ? ? CZ D ARG 125 ? ? NH1 D ARG 125 ? ? 124.72 120.30 4.42   0.50 N 
53 1 CA  D ARG 164 ? ? CB D ARG 164 ? ? CG  D ARG 164 ? ? 130.11 113.40 16.71  2.20 N 
54 1 NE  D ARG 207 ? ? CZ D ARG 207 ? ? NH2 D ARG 207 ? ? 124.74 120.30 4.44   0.50 N 
55 1 CA  D THR 232 ? ? CB D THR 232 ? ? OG1 D THR 232 ? ? 93.56  109.00 -15.44 2.10 N 
56 1 NE  D ARG 276 ? ? CZ D ARG 276 ? ? NH1 D ARG 276 ? ? 115.02 120.30 -5.28  0.50 N 
57 1 CB  E ASP 57  ? ? CA E ASP 57  ? ? C   E ASP 57  ? ? 93.97  110.40 -16.43 2.00 N 
58 1 CG  E ARG 87  ? ? CD E ARG 87  ? ? NE  E ARG 87  ? ? 88.23  111.80 -23.57 2.10 N 
59 1 N   E ARG 95  ? ? CA E ARG 95  ? ? CB  E ARG 95  ? ? 99.03  110.60 -11.57 1.80 N 
60 1 CD  E ARG 111 ? ? NE E ARG 111 ? ? CZ  E ARG 111 ? ? 133.44 123.60 9.84   1.40 N 
61 1 CB  E ASP 113 ? ? CG E ASP 113 ? ? OD1 E ASP 113 ? ? 111.65 118.30 -6.65  0.90 N 
62 1 NE  E ARG 125 ? ? CZ E ARG 125 ? ? NH1 E ARG 125 ? ? 116.84 120.30 -3.46  0.50 N 
63 1 CA  E ARG 163 ? ? CB E ARG 163 ? ? CG  E ARG 163 ? ? 128.72 113.40 15.32  2.20 N 
64 1 CA  E ARG 164 ? ? CB E ARG 164 ? ? CG  E ARG 164 ? ? 131.42 113.40 18.02  2.20 N 
65 1 NE  E ARG 207 ? ? CZ E ARG 207 ? ? NH1 E ARG 207 ? ? 123.76 120.30 3.46   0.50 N 
66 1 CB  E ASP 212 ? ? CG E ASP 212 ? ? OD2 E ASP 212 ? ? 112.49 118.30 -5.81  0.90 N 
67 1 CA  E THR 232 ? ? CB E THR 232 ? ? OG1 E THR 232 ? ? 93.29  109.00 -15.71 2.10 N 
68 1 CG  E MET 273 ? ? SD E MET 273 ? ? CE  E MET 273 ? ? 109.81 100.20 9.61   1.60 N 
69 1 NE  E ARG 276 ? ? CZ E ARG 276 ? ? NH2 E ARG 276 ? ? 116.75 120.30 -3.55  0.50 N 
70 1 CB  F LEU 24  ? ? CG F LEU 24  ? ? CD2 F LEU 24  ? ? 99.95  111.00 -11.05 1.70 N 
71 1 NE  F ARG 53  ? ? CZ F ARG 53  ? ? NH2 F ARG 53  ? ? 126.77 120.30 6.47   0.50 N 
72 1 CB  F ASP 57  ? ? CA F ASP 57  ? ? C   F ASP 57  ? ? 97.23  110.40 -13.17 2.00 N 
73 1 CG  F ARG 87  ? ? CD F ARG 87  ? ? NE  F ARG 87  ? ? 95.69  111.80 -16.11 2.10 N 
74 1 NE  F ARG 87  ? ? CZ F ARG 87  ? ? NH2 F ARG 87  ? ? 116.54 120.30 -3.76  0.50 N 
75 1 NE  F ARG 108 ? ? CZ F ARG 108 ? ? NH2 F ARG 108 ? ? 123.57 120.30 3.27   0.50 N 
76 1 CD  F ARG 111 ? ? NE F ARG 111 ? ? CZ  F ARG 111 ? ? 133.19 123.60 9.59   1.40 N 
77 1 NE  F ARG 111 ? ? CZ F ARG 111 ? ? NH2 F ARG 111 ? ? 123.47 120.30 3.17   0.50 N 
78 1 CB  F ASP 113 ? ? CG F ASP 113 ? ? OD1 F ASP 113 ? ? 112.13 118.30 -6.17  0.90 N 
79 1 CB  F ASP 152 ? ? CG F ASP 152 ? ? OD1 F ASP 152 ? ? 112.83 118.30 -5.47  0.90 N 
80 1 CA  F THR 158 ? ? CB F THR 158 ? ? OG1 F THR 158 ? ? 94.51  109.00 -14.49 2.10 N 
81 1 CA  F ARG 163 ? ? CB F ARG 163 ? ? CG  F ARG 163 ? ? 131.23 113.40 17.83  2.20 N 
82 1 NE  F ARG 208 ? ? CZ F ARG 208 ? ? NH2 F ARG 208 ? ? 124.21 120.30 3.91   0.50 N 
83 1 CG  F MET 210 ? ? SD F MET 210 ? ? CE  F MET 210 ? ? 87.27  100.20 -12.93 1.60 N 
84 1 OE1 F GLU 240 ? ? CD F GLU 240 ? ? OE2 F GLU 240 ? ? 130.81 123.30 7.51   1.20 N 
85 1 NE  F ARG 265 ? ? CZ F ARG 265 ? ? NH1 F ARG 265 ? ? 123.36 120.30 3.06   0.50 N 
86 1 CB  F GLU 268 ? ? CG F GLU 268 ? ? CD  F GLU 268 ? ? 95.60  114.20 -18.60 2.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 16  ? ? -41.20  158.01  
2  1 PHE A 142 ? ? 85.94   -122.41 
3  1 ASP A 143 ? ? -112.03 64.89   
4  1 ASP A 172 ? ? -152.36 72.20   
5  1 ASP A 244 ? ? -142.05 59.71   
6  1 PRO B 16  ? ? -39.37  157.47  
7  1 ASP B 172 ? ? -154.36 68.27   
8  1 ASP B 244 ? ? -144.76 54.51   
9  1 PRO C 16  ? ? -44.70  163.94  
10 1 PHE C 142 ? ? 83.37   -133.09 
11 1 ASP C 172 ? ? -152.79 67.14   
12 1 ASP C 218 ? ? -38.56  -35.63  
13 1 PRO D 16  ? ? -37.62  159.40  
14 1 GLU D 144 ? ? 49.56   28.04   
15 1 ASP D 172 ? ? -154.99 68.60   
16 1 ASP D 244 ? ? -145.90 58.77   
17 1 PRO E 16  ? ? -45.28  164.82  
18 1 ASP E 172 ? ? -154.64 69.00   
19 1 ASP E 244 ? ? -144.21 59.36   
20 1 PRO F 16  ? ? -41.11  161.20  
21 1 ASP F 172 ? ? -154.06 67.59   
22 1 PRO F 234 ? ? -27.98  -46.57  
23 1 ASP F 235 ? ? -38.70  -26.28  
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 GLU B 7   ? ? PRO B 8   ? ? -127.92 
2 1 GLU D 7   ? ? PRO D 8   ? ? 132.15  
3 1 TYR D 141 ? ? PHE D 142 ? ? -147.44 
4 1 GLU E 7   ? ? PRO E 8   ? ? 141.25  
5 1 GLU F 7   ? ? PRO F 8   ? ? 124.46  
6 1 GLY F 233 ? ? PRO F 234 ? ? 146.56  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 37  ? ? 0.079 'SIDE CHAIN' 
2  1 ARG A 95  ? ? 0.245 'SIDE CHAIN' 
3  1 ARG A 125 ? ? 0.091 'SIDE CHAIN' 
4  1 ARG A 127 ? ? 0.083 'SIDE CHAIN' 
5  1 ARG A 208 ? ? 0.095 'SIDE CHAIN' 
6  1 ARG A 253 ? ? 0.090 'SIDE CHAIN' 
7  1 ARG A 265 ? ? 0.098 'SIDE CHAIN' 
8  1 ARG B 59  ? ? 0.109 'SIDE CHAIN' 
9  1 ARG B 125 ? ? 0.090 'SIDE CHAIN' 
10 1 ARG B 207 ? ? 0.107 'SIDE CHAIN' 
11 1 ARG B 253 ? ? 0.080 'SIDE CHAIN' 
12 1 ARG C 37  ? ? 0.108 'SIDE CHAIN' 
13 1 ARG C 59  ? ? 0.142 'SIDE CHAIN' 
14 1 ARG C 87  ? ? 0.160 'SIDE CHAIN' 
15 1 ARG C 95  ? ? 0.112 'SIDE CHAIN' 
16 1 ARG C 111 ? ? 0.082 'SIDE CHAIN' 
17 1 ARG C 125 ? ? 0.079 'SIDE CHAIN' 
18 1 ARG C 127 ? ? 0.103 'SIDE CHAIN' 
19 1 ARG C 164 ? ? 0.098 'SIDE CHAIN' 
20 1 ARG D 37  ? ? 0.140 'SIDE CHAIN' 
21 1 ARG D 87  ? ? 0.146 'SIDE CHAIN' 
22 1 ARG D 95  ? ? 0.221 'SIDE CHAIN' 
23 1 ARG D 203 ? ? 0.117 'SIDE CHAIN' 
24 1 ARG D 253 ? ? 0.088 'SIDE CHAIN' 
25 1 ARG E 37  ? ? 0.118 'SIDE CHAIN' 
26 1 ARG E 59  ? ? 0.076 'SIDE CHAIN' 
27 1 ARG E 87  ? ? 0.195 'SIDE CHAIN' 
28 1 ARG E 95  ? ? 0.187 'SIDE CHAIN' 
29 1 ARG E 125 ? ? 0.131 'SIDE CHAIN' 
30 1 ARG E 203 ? ? 0.114 'SIDE CHAIN' 
31 1 ARG E 253 ? ? 0.089 'SIDE CHAIN' 
32 1 ARG F 37  ? ? 0.073 'SIDE CHAIN' 
33 1 ARG F 125 ? ? 0.099 'SIDE CHAIN' 
34 1 ARG F 145 ? ? 0.082 'SIDE CHAIN' 
35 1 ARG F 203 ? ? 0.168 'SIDE CHAIN' 
36 1 ARG F 207 ? ? 0.082 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A GLY 2   ? A GLY 2   
3  1 Y 1 A GLY 3   ? A GLY 3   
4  1 Y 1 A GLU 4   ? A GLU 4   
5  1 Y 1 A VAL 5   ? A VAL 5   
6  1 Y 1 A GLU 6   ? A GLU 6   
7  1 Y 1 A GLU 7   ? A GLU 7   
8  1 Y 1 B MET 1   ? B MET 1   
9  1 Y 1 B GLY 2   ? B GLY 2   
10 1 Y 1 B GLY 3   ? B GLY 3   
11 1 Y 1 B GLU 4   ? B GLU 4   
12 1 Y 1 B VAL 5   ? B VAL 5   
13 1 Y 1 B GLU 6   ? B GLU 6   
14 1 Y 1 B LEU 312 ? B LEU 312 
15 1 Y 1 C MET 1   ? C MET 1   
16 1 Y 1 C GLY 2   ? C GLY 2   
17 1 Y 1 C GLY 3   ? C GLY 3   
18 1 Y 1 C GLU 4   ? C GLU 4   
19 1 Y 1 C VAL 5   ? C VAL 5   
20 1 Y 1 C GLU 6   ? C GLU 6   
21 1 Y 1 D MET 1   ? D MET 1   
22 1 Y 1 D GLY 2   ? D GLY 2   
23 1 Y 1 D GLY 3   ? D GLY 3   
24 1 Y 1 D GLU 4   ? D GLU 4   
25 1 Y 1 D VAL 5   ? D VAL 5   
26 1 Y 1 D GLU 6   ? D GLU 6   
27 1 Y 1 E MET 1   ? E MET 1   
28 1 Y 1 E GLY 2   ? E GLY 2   
29 1 Y 1 E GLY 3   ? E GLY 3   
30 1 Y 1 E GLU 4   ? E GLU 4   
31 1 Y 1 E VAL 5   ? E VAL 5   
32 1 Y 1 E GLU 6   ? E GLU 6   
33 1 Y 1 F MET 1   ? F MET 1   
34 1 Y 1 F GLY 2   ? F GLY 2   
35 1 Y 1 F GLY 3   ? F GLY 3   
36 1 Y 1 F GLU 4   ? F GLU 4   
37 1 Y 1 F VAL 5   ? F VAL 5   
38 1 Y 1 F GLU 6   ? F GLU 6   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HEM CHA  C  N N 137 
HEM CHB  C  N N 138 
HEM CHC  C  N N 139 
HEM CHD  C  N N 140 
HEM C1A  C  Y N 141 
HEM C2A  C  Y N 142 
HEM C3A  C  Y N 143 
HEM C4A  C  Y N 144 
HEM CMA  C  N N 145 
HEM CAA  C  N N 146 
HEM CBA  C  N N 147 
HEM CGA  C  N N 148 
HEM O1A  O  N N 149 
HEM O2A  O  N N 150 
HEM C1B  C  N N 151 
HEM C2B  C  N N 152 
HEM C3B  C  N N 153 
HEM C4B  C  N N 154 
HEM CMB  C  N N 155 
HEM CAB  C  N N 156 
HEM CBB  C  N N 157 
HEM C1C  C  Y N 158 
HEM C2C  C  Y N 159 
HEM C3C  C  Y N 160 
HEM C4C  C  Y N 161 
HEM CMC  C  N N 162 
HEM CAC  C  N N 163 
HEM CBC  C  N N 164 
HEM C1D  C  N N 165 
HEM C2D  C  N N 166 
HEM C3D  C  N N 167 
HEM C4D  C  N N 168 
HEM CMD  C  N N 169 
HEM CAD  C  N N 170 
HEM CBD  C  N N 171 
HEM CGD  C  N N 172 
HEM O1D  O  N N 173 
HEM O2D  O  N N 174 
HEM NA   N  Y N 175 
HEM NB   N  N N 176 
HEM NC   N  Y N 177 
HEM ND   N  N N 178 
HEM FE   FE N N 179 
HEM HHB  H  N N 180 
HEM HHC  H  N N 181 
HEM HHD  H  N N 182 
HEM HMA  H  N N 183 
HEM HMAA H  N N 184 
HEM HMAB H  N N 185 
HEM HAA  H  N N 186 
HEM HAAA H  N N 187 
HEM HBA  H  N N 188 
HEM HBAA H  N N 189 
HEM HMB  H  N N 190 
HEM HMBA H  N N 191 
HEM HMBB H  N N 192 
HEM HAB  H  N N 193 
HEM HBB  H  N N 194 
HEM HBBA H  N N 195 
HEM HMC  H  N N 196 
HEM HMCA H  N N 197 
HEM HMCB H  N N 198 
HEM HAC  H  N N 199 
HEM HBC  H  N N 200 
HEM HBCA H  N N 201 
HEM HMD  H  N N 202 
HEM HMDA H  N N 203 
HEM HMDB H  N N 204 
HEM HAD  H  N N 205 
HEM HADA H  N N 206 
HEM HBD  H  N N 207 
HEM HBDA H  N N 208 
HEM H2A  H  N N 209 
HEM H2D  H  N N 210 
HEM HHA  H  N N 211 
HIS N    N  N N 212 
HIS CA   C  N S 213 
HIS C    C  N N 214 
HIS O    O  N N 215 
HIS CB   C  N N 216 
HIS CG   C  Y N 217 
HIS ND1  N  Y N 218 
HIS CD2  C  Y N 219 
HIS CE1  C  Y N 220 
HIS NE2  N  Y N 221 
HIS OXT  O  N N 222 
HIS H    H  N N 223 
HIS H2   H  N N 224 
HIS HA   H  N N 225 
HIS HB2  H  N N 226 
HIS HB3  H  N N 227 
HIS HD1  H  N N 228 
HIS HD2  H  N N 229 
HIS HE1  H  N N 230 
HIS HE2  H  N N 231 
HIS HXT  H  N N 232 
HOH O    O  N N 233 
HOH H1   H  N N 234 
HOH H2   H  N N 235 
ILE N    N  N N 236 
ILE CA   C  N S 237 
ILE C    C  N N 238 
ILE O    O  N N 239 
ILE CB   C  N S 240 
ILE CG1  C  N N 241 
ILE CG2  C  N N 242 
ILE CD1  C  N N 243 
ILE OXT  O  N N 244 
ILE H    H  N N 245 
ILE H2   H  N N 246 
ILE HA   H  N N 247 
ILE HB   H  N N 248 
ILE HG12 H  N N 249 
ILE HG13 H  N N 250 
ILE HG21 H  N N 251 
ILE HG22 H  N N 252 
ILE HG23 H  N N 253 
ILE HD11 H  N N 254 
ILE HD12 H  N N 255 
ILE HD13 H  N N 256 
ILE HXT  H  N N 257 
LEU N    N  N N 258 
LEU CA   C  N S 259 
LEU C    C  N N 260 
LEU O    O  N N 261 
LEU CB   C  N N 262 
LEU CG   C  N N 263 
LEU CD1  C  N N 264 
LEU CD2  C  N N 265 
LEU OXT  O  N N 266 
LEU H    H  N N 267 
LEU H2   H  N N 268 
LEU HA   H  N N 269 
LEU HB2  H  N N 270 
LEU HB3  H  N N 271 
LEU HG   H  N N 272 
LEU HD11 H  N N 273 
LEU HD12 H  N N 274 
LEU HD13 H  N N 275 
LEU HD21 H  N N 276 
LEU HD22 H  N N 277 
LEU HD23 H  N N 278 
LEU HXT  H  N N 279 
LYS N    N  N N 280 
LYS CA   C  N S 281 
LYS C    C  N N 282 
LYS O    O  N N 283 
LYS CB   C  N N 284 
LYS CG   C  N N 285 
LYS CD   C  N N 286 
LYS CE   C  N N 287 
LYS NZ   N  N N 288 
LYS OXT  O  N N 289 
LYS H    H  N N 290 
LYS H2   H  N N 291 
LYS HA   H  N N 292 
LYS HB2  H  N N 293 
LYS HB3  H  N N 294 
LYS HG2  H  N N 295 
LYS HG3  H  N N 296 
LYS HD2  H  N N 297 
LYS HD3  H  N N 298 
LYS HE2  H  N N 299 
LYS HE3  H  N N 300 
LYS HZ1  H  N N 301 
LYS HZ2  H  N N 302 
LYS HZ3  H  N N 303 
LYS HXT  H  N N 304 
MET N    N  N N 305 
MET CA   C  N S 306 
MET C    C  N N 307 
MET O    O  N N 308 
MET CB   C  N N 309 
MET CG   C  N N 310 
MET SD   S  N N 311 
MET CE   C  N N 312 
MET OXT  O  N N 313 
MET H    H  N N 314 
MET H2   H  N N 315 
MET HA   H  N N 316 
MET HB2  H  N N 317 
MET HB3  H  N N 318 
MET HG2  H  N N 319 
MET HG3  H  N N 320 
MET HE1  H  N N 321 
MET HE2  H  N N 322 
MET HE3  H  N N 323 
MET HXT  H  N N 324 
MG  MG   MG N N 325 
O   O    O  N N 326 
PG4 O1   O  N N 327 
PG4 C1   C  N N 328 
PG4 C2   C  N N 329 
PG4 O2   O  N N 330 
PG4 C3   C  N N 331 
PG4 C4   C  N N 332 
PG4 O3   O  N N 333 
PG4 C5   C  N N 334 
PG4 C6   C  N N 335 
PG4 O4   O  N N 336 
PG4 C7   C  N N 337 
PG4 C8   C  N N 338 
PG4 O5   O  N N 339 
PG4 HO1  H  N N 340 
PG4 H11  H  N N 341 
PG4 H12  H  N N 342 
PG4 H21  H  N N 343 
PG4 H22  H  N N 344 
PG4 H31  H  N N 345 
PG4 H32  H  N N 346 
PG4 H41  H  N N 347 
PG4 H42  H  N N 348 
PG4 H51  H  N N 349 
PG4 H52  H  N N 350 
PG4 H61  H  N N 351 
PG4 H62  H  N N 352 
PG4 H71  H  N N 353 
PG4 H72  H  N N 354 
PG4 H81  H  N N 355 
PG4 H82  H  N N 356 
PG4 HO5  H  N N 357 
PHE N    N  N N 358 
PHE CA   C  N S 359 
PHE C    C  N N 360 
PHE O    O  N N 361 
PHE CB   C  N N 362 
PHE CG   C  Y N 363 
PHE CD1  C  Y N 364 
PHE CD2  C  Y N 365 
PHE CE1  C  Y N 366 
PHE CE2  C  Y N 367 
PHE CZ   C  Y N 368 
PHE OXT  O  N N 369 
PHE H    H  N N 370 
PHE H2   H  N N 371 
PHE HA   H  N N 372 
PHE HB2  H  N N 373 
PHE HB3  H  N N 374 
PHE HD1  H  N N 375 
PHE HD2  H  N N 376 
PHE HE1  H  N N 377 
PHE HE2  H  N N 378 
PHE HZ   H  N N 379 
PHE HXT  H  N N 380 
PRO N    N  N N 381 
PRO CA   C  N S 382 
PRO C    C  N N 383 
PRO O    O  N N 384 
PRO CB   C  N N 385 
PRO CG   C  N N 386 
PRO CD   C  N N 387 
PRO OXT  O  N N 388 
PRO H    H  N N 389 
PRO HA   H  N N 390 
PRO HB2  H  N N 391 
PRO HB3  H  N N 392 
PRO HG2  H  N N 393 
PRO HG3  H  N N 394 
PRO HD2  H  N N 395 
PRO HD3  H  N N 396 
PRO HXT  H  N N 397 
SER N    N  N N 398 
SER CA   C  N S 399 
SER C    C  N N 400 
SER O    O  N N 401 
SER CB   C  N N 402 
SER OG   O  N N 403 
SER OXT  O  N N 404 
SER H    H  N N 405 
SER H2   H  N N 406 
SER HA   H  N N 407 
SER HB2  H  N N 408 
SER HB3  H  N N 409 
SER HG   H  N N 410 
SER HXT  H  N N 411 
THR N    N  N N 412 
THR CA   C  N S 413 
THR C    C  N N 414 
THR O    O  N N 415 
THR CB   C  N R 416 
THR OG1  O  N N 417 
THR CG2  C  N N 418 
THR OXT  O  N N 419 
THR H    H  N N 420 
THR H2   H  N N 421 
THR HA   H  N N 422 
THR HB   H  N N 423 
THR HG1  H  N N 424 
THR HG21 H  N N 425 
THR HG22 H  N N 426 
THR HG23 H  N N 427 
THR HXT  H  N N 428 
TRP N    N  N N 429 
TRP CA   C  N S 430 
TRP C    C  N N 431 
TRP O    O  N N 432 
TRP CB   C  N N 433 
TRP CG   C  Y N 434 
TRP CD1  C  Y N 435 
TRP CD2  C  Y N 436 
TRP NE1  N  Y N 437 
TRP CE2  C  Y N 438 
TRP CE3  C  Y N 439 
TRP CZ2  C  Y N 440 
TRP CZ3  C  Y N 441 
TRP CH2  C  Y N 442 
TRP OXT  O  N N 443 
TRP H    H  N N 444 
TRP H2   H  N N 445 
TRP HA   H  N N 446 
TRP HB2  H  N N 447 
TRP HB3  H  N N 448 
TRP HD1  H  N N 449 
TRP HE1  H  N N 450 
TRP HE3  H  N N 451 
TRP HZ2  H  N N 452 
TRP HZ3  H  N N 453 
TRP HH2  H  N N 454 
TRP HXT  H  N N 455 
TYR N    N  N N 456 
TYR CA   C  N S 457 
TYR C    C  N N 458 
TYR O    O  N N 459 
TYR CB   C  N N 460 
TYR CG   C  Y N 461 
TYR CD1  C  Y N 462 
TYR CD2  C  Y N 463 
TYR CE1  C  Y N 464 
TYR CE2  C  Y N 465 
TYR CZ   C  Y N 466 
TYR OH   O  N N 467 
TYR OXT  O  N N 468 
TYR H    H  N N 469 
TYR H2   H  N N 470 
TYR HA   H  N N 471 
TYR HB2  H  N N 472 
TYR HB3  H  N N 473 
TYR HD1  H  N N 474 
TYR HD2  H  N N 475 
TYR HE1  H  N N 476 
TYR HE2  H  N N 477 
TYR HH   H  N N 478 
TYR HXT  H  N N 479 
VAL N    N  N N 480 
VAL CA   C  N S 481 
VAL C    C  N N 482 
VAL O    O  N N 483 
VAL CB   C  N N 484 
VAL CG1  C  N N 485 
VAL CG2  C  N N 486 
VAL OXT  O  N N 487 
VAL H    H  N N 488 
VAL H2   H  N N 489 
VAL HA   H  N N 490 
VAL HB   H  N N 491 
VAL HG11 H  N N 492 
VAL HG12 H  N N 493 
VAL HG13 H  N N 494 
VAL HG21 H  N N 495 
VAL HG22 H  N N 496 
VAL HG23 H  N N 497 
VAL HXT  H  N N 498 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HEM CHA C1A  sing N N 129 
HEM CHA C4D  doub N N 130 
HEM CHA HHA  sing N N 131 
HEM CHB C4A  sing N N 132 
HEM CHB C1B  doub N N 133 
HEM CHB HHB  sing N N 134 
HEM CHC C4B  sing N N 135 
HEM CHC C1C  doub N N 136 
HEM CHC HHC  sing N N 137 
HEM CHD C4C  doub N N 138 
HEM CHD C1D  sing N N 139 
HEM CHD HHD  sing N N 140 
HEM C1A C2A  doub Y N 141 
HEM C1A NA   sing Y N 142 
HEM C2A C3A  sing Y N 143 
HEM C2A CAA  sing N N 144 
HEM C3A C4A  doub Y N 145 
HEM C3A CMA  sing N N 146 
HEM C4A NA   sing Y N 147 
HEM CMA HMA  sing N N 148 
HEM CMA HMAA sing N N 149 
HEM CMA HMAB sing N N 150 
HEM CAA CBA  sing N N 151 
HEM CAA HAA  sing N N 152 
HEM CAA HAAA sing N N 153 
HEM CBA CGA  sing N N 154 
HEM CBA HBA  sing N N 155 
HEM CBA HBAA sing N N 156 
HEM CGA O1A  doub N N 157 
HEM CGA O2A  sing N N 158 
HEM C1B C2B  sing N N 159 
HEM C1B NB   sing N N 160 
HEM C2B C3B  doub N N 161 
HEM C2B CMB  sing N N 162 
HEM C3B C4B  sing N N 163 
HEM C3B CAB  sing N N 164 
HEM C4B NB   doub N N 165 
HEM CMB HMB  sing N N 166 
HEM CMB HMBA sing N N 167 
HEM CMB HMBB sing N N 168 
HEM CAB CBB  doub N N 169 
HEM CAB HAB  sing N N 170 
HEM CBB HBB  sing N N 171 
HEM CBB HBBA sing N N 172 
HEM C1C C2C  sing Y N 173 
HEM C1C NC   sing Y N 174 
HEM C2C C3C  doub Y N 175 
HEM C2C CMC  sing N N 176 
HEM C3C C4C  sing Y N 177 
HEM C3C CAC  sing N N 178 
HEM C4C NC   sing Y N 179 
HEM CMC HMC  sing N N 180 
HEM CMC HMCA sing N N 181 
HEM CMC HMCB sing N N 182 
HEM CAC CBC  doub N N 183 
HEM CAC HAC  sing N N 184 
HEM CBC HBC  sing N N 185 
HEM CBC HBCA sing N N 186 
HEM C1D C2D  sing N N 187 
HEM C1D ND   doub N N 188 
HEM C2D C3D  doub N N 189 
HEM C2D CMD  sing N N 190 
HEM C3D C4D  sing N N 191 
HEM C3D CAD  sing N N 192 
HEM C4D ND   sing N N 193 
HEM CMD HMD  sing N N 194 
HEM CMD HMDA sing N N 195 
HEM CMD HMDB sing N N 196 
HEM CAD CBD  sing N N 197 
HEM CAD HAD  sing N N 198 
HEM CAD HADA sing N N 199 
HEM CBD CGD  sing N N 200 
HEM CBD HBD  sing N N 201 
HEM CBD HBDA sing N N 202 
HEM CGD O1D  doub N N 203 
HEM CGD O2D  sing N N 204 
HEM O2A H2A  sing N N 205 
HEM O2D H2D  sing N N 206 
HEM FE  NA   sing N N 207 
HEM FE  NB   sing N N 208 
HEM FE  NC   sing N N 209 
HEM FE  ND   sing N N 210 
HIS N   CA   sing N N 211 
HIS N   H    sing N N 212 
HIS N   H2   sing N N 213 
HIS CA  C    sing N N 214 
HIS CA  CB   sing N N 215 
HIS CA  HA   sing N N 216 
HIS C   O    doub N N 217 
HIS C   OXT  sing N N 218 
HIS CB  CG   sing N N 219 
HIS CB  HB2  sing N N 220 
HIS CB  HB3  sing N N 221 
HIS CG  ND1  sing Y N 222 
HIS CG  CD2  doub Y N 223 
HIS ND1 CE1  doub Y N 224 
HIS ND1 HD1  sing N N 225 
HIS CD2 NE2  sing Y N 226 
HIS CD2 HD2  sing N N 227 
HIS CE1 NE2  sing Y N 228 
HIS CE1 HE1  sing N N 229 
HIS NE2 HE2  sing N N 230 
HIS OXT HXT  sing N N 231 
HOH O   H1   sing N N 232 
HOH O   H2   sing N N 233 
ILE N   CA   sing N N 234 
ILE N   H    sing N N 235 
ILE N   H2   sing N N 236 
ILE CA  C    sing N N 237 
ILE CA  CB   sing N N 238 
ILE CA  HA   sing N N 239 
ILE C   O    doub N N 240 
ILE C   OXT  sing N N 241 
ILE CB  CG1  sing N N 242 
ILE CB  CG2  sing N N 243 
ILE CB  HB   sing N N 244 
ILE CG1 CD1  sing N N 245 
ILE CG1 HG12 sing N N 246 
ILE CG1 HG13 sing N N 247 
ILE CG2 HG21 sing N N 248 
ILE CG2 HG22 sing N N 249 
ILE CG2 HG23 sing N N 250 
ILE CD1 HD11 sing N N 251 
ILE CD1 HD12 sing N N 252 
ILE CD1 HD13 sing N N 253 
ILE OXT HXT  sing N N 254 
LEU N   CA   sing N N 255 
LEU N   H    sing N N 256 
LEU N   H2   sing N N 257 
LEU CA  C    sing N N 258 
LEU CA  CB   sing N N 259 
LEU CA  HA   sing N N 260 
LEU C   O    doub N N 261 
LEU C   OXT  sing N N 262 
LEU CB  CG   sing N N 263 
LEU CB  HB2  sing N N 264 
LEU CB  HB3  sing N N 265 
LEU CG  CD1  sing N N 266 
LEU CG  CD2  sing N N 267 
LEU CG  HG   sing N N 268 
LEU CD1 HD11 sing N N 269 
LEU CD1 HD12 sing N N 270 
LEU CD1 HD13 sing N N 271 
LEU CD2 HD21 sing N N 272 
LEU CD2 HD22 sing N N 273 
LEU CD2 HD23 sing N N 274 
LEU OXT HXT  sing N N 275 
LYS N   CA   sing N N 276 
LYS N   H    sing N N 277 
LYS N   H2   sing N N 278 
LYS CA  C    sing N N 279 
LYS CA  CB   sing N N 280 
LYS CA  HA   sing N N 281 
LYS C   O    doub N N 282 
LYS C   OXT  sing N N 283 
LYS CB  CG   sing N N 284 
LYS CB  HB2  sing N N 285 
LYS CB  HB3  sing N N 286 
LYS CG  CD   sing N N 287 
LYS CG  HG2  sing N N 288 
LYS CG  HG3  sing N N 289 
LYS CD  CE   sing N N 290 
LYS CD  HD2  sing N N 291 
LYS CD  HD3  sing N N 292 
LYS CE  NZ   sing N N 293 
LYS CE  HE2  sing N N 294 
LYS CE  HE3  sing N N 295 
LYS NZ  HZ1  sing N N 296 
LYS NZ  HZ2  sing N N 297 
LYS NZ  HZ3  sing N N 298 
LYS OXT HXT  sing N N 299 
MET N   CA   sing N N 300 
MET N   H    sing N N 301 
MET N   H2   sing N N 302 
MET CA  C    sing N N 303 
MET CA  CB   sing N N 304 
MET CA  HA   sing N N 305 
MET C   O    doub N N 306 
MET C   OXT  sing N N 307 
MET CB  CG   sing N N 308 
MET CB  HB2  sing N N 309 
MET CB  HB3  sing N N 310 
MET CG  SD   sing N N 311 
MET CG  HG2  sing N N 312 
MET CG  HG3  sing N N 313 
MET SD  CE   sing N N 314 
MET CE  HE1  sing N N 315 
MET CE  HE2  sing N N 316 
MET CE  HE3  sing N N 317 
MET OXT HXT  sing N N 318 
PG4 O1  C1   sing N N 319 
PG4 O1  HO1  sing N N 320 
PG4 C1  C2   sing N N 321 
PG4 C1  H11  sing N N 322 
PG4 C1  H12  sing N N 323 
PG4 C2  O2   sing N N 324 
PG4 C2  H21  sing N N 325 
PG4 C2  H22  sing N N 326 
PG4 O2  C3   sing N N 327 
PG4 C3  C4   sing N N 328 
PG4 C3  H31  sing N N 329 
PG4 C3  H32  sing N N 330 
PG4 C4  O3   sing N N 331 
PG4 C4  H41  sing N N 332 
PG4 C4  H42  sing N N 333 
PG4 O3  C5   sing N N 334 
PG4 C5  C6   sing N N 335 
PG4 C5  H51  sing N N 336 
PG4 C5  H52  sing N N 337 
PG4 C6  O4   sing N N 338 
PG4 C6  H61  sing N N 339 
PG4 C6  H62  sing N N 340 
PG4 O4  C7   sing N N 341 
PG4 C7  C8   sing N N 342 
PG4 C7  H71  sing N N 343 
PG4 C7  H72  sing N N 344 
PG4 C8  O5   sing N N 345 
PG4 C8  H81  sing N N 346 
PG4 C8  H82  sing N N 347 
PG4 O5  HO5  sing N N 348 
PHE N   CA   sing N N 349 
PHE N   H    sing N N 350 
PHE N   H2   sing N N 351 
PHE CA  C    sing N N 352 
PHE CA  CB   sing N N 353 
PHE CA  HA   sing N N 354 
PHE C   O    doub N N 355 
PHE C   OXT  sing N N 356 
PHE CB  CG   sing N N 357 
PHE CB  HB2  sing N N 358 
PHE CB  HB3  sing N N 359 
PHE CG  CD1  doub Y N 360 
PHE CG  CD2  sing Y N 361 
PHE CD1 CE1  sing Y N 362 
PHE CD1 HD1  sing N N 363 
PHE CD2 CE2  doub Y N 364 
PHE CD2 HD2  sing N N 365 
PHE CE1 CZ   doub Y N 366 
PHE CE1 HE1  sing N N 367 
PHE CE2 CZ   sing Y N 368 
PHE CE2 HE2  sing N N 369 
PHE CZ  HZ   sing N N 370 
PHE OXT HXT  sing N N 371 
PRO N   CA   sing N N 372 
PRO N   CD   sing N N 373 
PRO N   H    sing N N 374 
PRO CA  C    sing N N 375 
PRO CA  CB   sing N N 376 
PRO CA  HA   sing N N 377 
PRO C   O    doub N N 378 
PRO C   OXT  sing N N 379 
PRO CB  CG   sing N N 380 
PRO CB  HB2  sing N N 381 
PRO CB  HB3  sing N N 382 
PRO CG  CD   sing N N 383 
PRO CG  HG2  sing N N 384 
PRO CG  HG3  sing N N 385 
PRO CD  HD2  sing N N 386 
PRO CD  HD3  sing N N 387 
PRO OXT HXT  sing N N 388 
SER N   CA   sing N N 389 
SER N   H    sing N N 390 
SER N   H2   sing N N 391 
SER CA  C    sing N N 392 
SER CA  CB   sing N N 393 
SER CA  HA   sing N N 394 
SER C   O    doub N N 395 
SER C   OXT  sing N N 396 
SER CB  OG   sing N N 397 
SER CB  HB2  sing N N 398 
SER CB  HB3  sing N N 399 
SER OG  HG   sing N N 400 
SER OXT HXT  sing N N 401 
THR N   CA   sing N N 402 
THR N   H    sing N N 403 
THR N   H2   sing N N 404 
THR CA  C    sing N N 405 
THR CA  CB   sing N N 406 
THR CA  HA   sing N N 407 
THR C   O    doub N N 408 
THR C   OXT  sing N N 409 
THR CB  OG1  sing N N 410 
THR CB  CG2  sing N N 411 
THR CB  HB   sing N N 412 
THR OG1 HG1  sing N N 413 
THR CG2 HG21 sing N N 414 
THR CG2 HG22 sing N N 415 
THR CG2 HG23 sing N N 416 
THR OXT HXT  sing N N 417 
TRP N   CA   sing N N 418 
TRP N   H    sing N N 419 
TRP N   H2   sing N N 420 
TRP CA  C    sing N N 421 
TRP CA  CB   sing N N 422 
TRP CA  HA   sing N N 423 
TRP C   O    doub N N 424 
TRP C   OXT  sing N N 425 
TRP CB  CG   sing N N 426 
TRP CB  HB2  sing N N 427 
TRP CB  HB3  sing N N 428 
TRP CG  CD1  doub Y N 429 
TRP CG  CD2  sing Y N 430 
TRP CD1 NE1  sing Y N 431 
TRP CD1 HD1  sing N N 432 
TRP CD2 CE2  doub Y N 433 
TRP CD2 CE3  sing Y N 434 
TRP NE1 CE2  sing Y N 435 
TRP NE1 HE1  sing N N 436 
TRP CE2 CZ2  sing Y N 437 
TRP CE3 CZ3  doub Y N 438 
TRP CE3 HE3  sing N N 439 
TRP CZ2 CH2  doub Y N 440 
TRP CZ2 HZ2  sing N N 441 
TRP CZ3 CH2  sing Y N 442 
TRP CZ3 HZ3  sing N N 443 
TRP CH2 HH2  sing N N 444 
TRP OXT HXT  sing N N 445 
TYR N   CA   sing N N 446 
TYR N   H    sing N N 447 
TYR N   H2   sing N N 448 
TYR CA  C    sing N N 449 
TYR CA  CB   sing N N 450 
TYR CA  HA   sing N N 451 
TYR C   O    doub N N 452 
TYR C   OXT  sing N N 453 
TYR CB  CG   sing N N 454 
TYR CB  HB2  sing N N 455 
TYR CB  HB3  sing N N 456 
TYR CG  CD1  doub Y N 457 
TYR CG  CD2  sing Y N 458 
TYR CD1 CE1  sing Y N 459 
TYR CD1 HD1  sing N N 460 
TYR CD2 CE2  doub Y N 461 
TYR CD2 HD2  sing N N 462 
TYR CE1 CZ   doub Y N 463 
TYR CE1 HE1  sing N N 464 
TYR CE2 CZ   sing Y N 465 
TYR CE2 HE2  sing N N 466 
TYR CZ  OH   sing N N 467 
TYR OH  HH   sing N N 468 
TYR OXT HXT  sing N N 469 
VAL N   CA   sing N N 470 
VAL N   H    sing N N 471 
VAL N   H2   sing N N 472 
VAL CA  C    sing N N 473 
VAL CA  CB   sing N N 474 
VAL CA  HA   sing N N 475 
VAL C   O    doub N N 476 
VAL C   OXT  sing N N 477 
VAL CB  CG1  sing N N 478 
VAL CB  CG2  sing N N 479 
VAL CB  HB   sing N N 480 
VAL CG1 HG11 sing N N 481 
VAL CG1 HG12 sing N N 482 
VAL CG1 HG13 sing N N 483 
VAL CG2 HG21 sing N N 484 
VAL CG2 HG22 sing N N 485 
VAL CG2 HG23 sing N N 486 
VAL OXT HXT  sing N N 487 
# 
_pdbx_audit_support.funding_organization   'Biotechnology and Biological Sciences Research Council (BBSRC)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           BB/R021015/1 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6YRD 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_serial_crystallography_data_reduction.crystal_hits          21858 
_pdbx_serial_crystallography_data_reduction.diffrn_id             1 
_pdbx_serial_crystallography_data_reduction.droplet_hits          ? 
_pdbx_serial_crystallography_data_reduction.frame_hits            ? 
_pdbx_serial_crystallography_data_reduction.frames_failed_index   ? 
_pdbx_serial_crystallography_data_reduction.frames_indexed        ? 
_pdbx_serial_crystallography_data_reduction.frames_total          ? 
_pdbx_serial_crystallography_data_reduction.lattices_indexed      ? 
_pdbx_serial_crystallography_data_reduction.lattices_merged       ? 
_pdbx_serial_crystallography_data_reduction.xfel_pulse_events     ? 
_pdbx_serial_crystallography_data_reduction.xfel_run_numbers      ? 
# 
_pdbx_serial_crystallography_measurement.collection_time_total        ? 
_pdbx_serial_crystallography_measurement.collimation                  ? 
_pdbx_serial_crystallography_measurement.diffrn_id                    1 
_pdbx_serial_crystallography_measurement.focal_spot_size              ? 
_pdbx_serial_crystallography_measurement.photons_per_pulse            ? 
_pdbx_serial_crystallography_measurement.pulse_duration               ? 
_pdbx_serial_crystallography_measurement.pulse_energy                 2.05e-9 
_pdbx_serial_crystallography_measurement.pulse_photon_energy          ? 
_pdbx_serial_crystallography_measurement.source_distance              ? 
_pdbx_serial_crystallography_measurement.source_size                  64 
_pdbx_serial_crystallography_measurement.xfel_pulse_repetition_rate   ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   'silicon chip' 
_pdbx_serial_crystallography_sample_delivery.method        'fixed target' 
# 
_pdbx_serial_crystallography_sample_delivery_fixed_target.crystals_per_unit               25600 
_pdbx_serial_crystallography_sample_delivery_fixed_target.description                     ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.details                         ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.diffrn_id                       1 
_pdbx_serial_crystallography_sample_delivery_fixed_target.motion_control                  ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_dehydration_prevention   mylar 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_holding                  'silicone chip' 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_solvent                  ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_unit_size                ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.support_base                    ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.velocity_horizontal             ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.velocity_vertical               ? 
# 
_atom_sites.entry_id                    9EWJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011514 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008204 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005011 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
FE 
MG 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . PRO A 1 8   ? -0.625  16.532  47.554  1.00 67.61  ? 8   PRO A N   1 
ATOM   2     C  CA  . PRO A 1 8   ? -1.211  16.614  46.191  1.00 61.79  ? 8   PRO A CA  1 
ATOM   3     C  C   . PRO A 1 8   ? -0.222  16.307  45.051  1.00 50.80  ? 8   PRO A C   1 
ATOM   4     O  O   . PRO A 1 8   ? 0.751   17.037  44.985  1.00 53.45  ? 8   PRO A O   1 
ATOM   5     C  CB  . PRO A 1 8   ? -1.777  18.087  46.126  1.00 58.36  ? 8   PRO A CB  1 
ATOM   6     C  CG  . PRO A 1 8   ? -1.329  18.741  47.471  1.00 58.71  ? 8   PRO A CG  1 
ATOM   7     C  CD  . PRO A 1 8   ? -0.219  17.846  48.074  1.00 60.63  ? 8   PRO A CD  1 
ATOM   8     N  N   . GLU A 1 9   ? -0.403  15.197  44.263  1.00 50.42  ? 9   GLU A N   1 
ATOM   9     C  CA  . GLU A 1 9   ? 0.517   14.667  43.222  1.00 48.45  ? 9   GLU A CA  1 
ATOM   10    C  C   . GLU A 1 9   ? 0.355   15.607  42.004  1.00 43.32  ? 9   GLU A C   1 
ATOM   11    O  O   . GLU A 1 9   ? -0.761  15.870  41.489  1.00 33.43  ? 9   GLU A O   1 
ATOM   12    C  CB  . GLU A 1 9   ? 0.395   13.118  42.965  1.00 54.61  ? 9   GLU A CB  1 
ATOM   13    C  CG  . GLU A 1 9   ? 1.017   12.402  41.734  1.00 42.73  ? 9   GLU A CG  1 
ATOM   14    N  N   . PRO A 1 10  ? 1.415   16.290  41.533  1.00 33.56  ? 10  PRO A N   1 
ATOM   15    C  CA  . PRO A 1 10  ? 1.340   17.030  40.258  1.00 34.33  ? 10  PRO A CA  1 
ATOM   16    C  C   . PRO A 1 10  ? 1.347   16.078  39.050  1.00 32.17  ? 10  PRO A C   1 
ATOM   17    O  O   . PRO A 1 10  ? 1.753   14.908  39.184  1.00 26.76  ? 10  PRO A O   1 
ATOM   18    C  CB  . PRO A 1 10  ? 2.584   17.917  40.290  1.00 34.30  ? 10  PRO A CB  1 
ATOM   19    C  CG  . PRO A 1 10  ? 3.577   17.046  41.012  1.00 36.70  ? 10  PRO A CG  1 
ATOM   20    C  CD  . PRO A 1 10  ? 2.701   16.467  42.174  1.00 35.01  ? 10  PRO A CD  1 
ATOM   21    N  N   . GLN A 1 11  ? 0.862   16.595  37.903  1.00 28.98  ? 11  GLN A N   1 
ATOM   22    C  CA  . GLN A 1 11  ? 1.033   15.934  36.632  1.00 29.42  ? 11  GLN A CA  1 
ATOM   23    C  C   . GLN A 1 11  ? 2.533   15.949  36.307  1.00 27.18  ? 11  GLN A C   1 
ATOM   24    O  O   . GLN A 1 11  ? 3.264   16.621  36.996  1.00 24.51  ? 11  GLN A O   1 
ATOM   25    C  CB  . GLN A 1 11  ? 0.201   16.629  35.548  1.00 28.23  ? 11  GLN A CB  1 
ATOM   26    C  CG  . GLN A 1 11  ? -1.292  16.412  35.627  1.00 24.44  ? 11  GLN A CG  1 
ATOM   27    C  CD  . GLN A 1 11  ? -1.928  17.035  34.420  1.00 24.16  ? 11  GLN A CD  1 
ATOM   28    O  OE1 . GLN A 1 11  ? -1.864  16.509  33.307  1.00 23.14  ? 11  GLN A OE1 1 
ATOM   29    N  NE2 . GLN A 1 11  ? -2.578  18.168  34.617  1.00 23.95  ? 11  GLN A NE2 1 
ATOM   30    N  N   . MET A 1 12  ? 2.932   15.300  35.201  1.00 28.27  ? 12  MET A N   1 
ATOM   31    C  CA  . MET A 1 12  ? 4.310   15.151  34.856  1.00 28.91  ? 12  MET A CA  1 
ATOM   32    C  C   . MET A 1 12  ? 4.838   16.423  34.189  1.00 31.10  ? 12  MET A C   1 
ATOM   33    O  O   . MET A 1 12  ? 5.417   16.393  33.086  1.00 33.12  ? 12  MET A O   1 
ATOM   34    C  CB  . MET A 1 12  ? 4.469   13.944  33.929  1.00 41.88  ? 12  MET A CB  1 
ATOM   35    C  CG  . MET A 1 12  ? 5.955   13.438  33.801  1.00 55.15  ? 12  MET A CG  1 
ATOM   36    S  SD  . MET A 1 12  ? 6.392   12.744  35.408  1.00 57.69  ? 12  MET A SD  1 
ATOM   37    C  CE  . MET A 1 12  ? 5.095   11.510  35.592  1.00 43.67  ? 12  MET A CE  1 
ATOM   38    N  N   . VAL A 1 13  ? 4.774   17.534  34.913  1.00 24.74  ? 13  VAL A N   1 
ATOM   39    C  CA  . VAL A 1 13  ? 5.287   18.755  34.346  1.00 27.04  ? 13  VAL A CA  1 
ATOM   40    C  C   . VAL A 1 13  ? 6.813   18.657  34.248  1.00 32.93  ? 13  VAL A C   1 
ATOM   41    O  O   . VAL A 1 13  ? 7.397   19.034  33.213  1.00 34.58  ? 13  VAL A O   1 
ATOM   42    C  CB  . VAL A 1 13  ? 4.819   19.972  35.133  1.00 25.90  ? 13  VAL A CB  1 
ATOM   43    C  CG1 . VAL A 1 13  ? 5.445   21.226  34.644  1.00 26.71  ? 13  VAL A CG1 1 
ATOM   44    C  CG2 . VAL A 1 13  ? 3.347   20.140  35.028  1.00 27.35  ? 13  VAL A CG2 1 
ATOM   45    N  N   . LEU A 1 14  ? 7.451   18.127  35.304  1.00 34.22  ? 14  LEU A N   1 
ATOM   46    C  CA  . LEU A 1 14  ? 8.909   17.965  35.312  1.00 38.26  ? 14  LEU A CA  1 
ATOM   47    C  C   . LEU A 1 14  ? 9.215   16.639  34.665  1.00 37.22  ? 14  LEU A C   1 
ATOM   48    O  O   . LEU A 1 14  ? 9.124   15.625  35.309  1.00 58.00  ? 14  LEU A O   1 
ATOM   49    C  CB  . LEU A 1 14  ? 9.502   18.013  36.711  1.00 39.31  ? 14  LEU A CB  1 
ATOM   50    C  CG  . LEU A 1 14  ? 8.926   19.156  37.546  1.00 51.11  ? 14  LEU A CG  1 
ATOM   51    C  CD1 . LEU A 1 14  ? 8.777   18.937  39.059  1.00 55.04  ? 14  LEU A CD1 1 
ATOM   52    C  CD2 . LEU A 1 14  ? 9.798   20.344  37.245  1.00 48.14  ? 14  LEU A CD2 1 
ATOM   53    N  N   . SER A 1 15  ? 9.457   16.628  33.375  1.00 38.16  ? 15  SER A N   1 
ATOM   54    C  CA  . SER A 1 15  ? 9.678   15.358  32.736  1.00 44.37  ? 15  SER A CA  1 
ATOM   55    C  C   . SER A 1 15  ? 11.186  15.205  32.496  1.00 40.11  ? 15  SER A C   1 
ATOM   56    O  O   . SER A 1 15  ? 11.912  16.167  32.369  1.00 44.40  ? 15  SER A O   1 
ATOM   57    C  CB  . SER A 1 15  ? 8.796   15.253  31.511  1.00 44.91  ? 15  SER A CB  1 
ATOM   58    O  OG  . SER A 1 15  ? 9.381   14.492  30.463  1.00 62.99  ? 15  SER A OG  1 
ATOM   59    N  N   . PRO A 1 16  ? 11.747  13.991  32.535  1.00 44.17  ? 16  PRO A N   1 
ATOM   60    C  CA  . PRO A 1 16  ? 12.993  13.728  31.818  1.00 51.50  ? 16  PRO A CA  1 
ATOM   61    C  C   . PRO A 1 16  ? 13.013  14.380  30.444  1.00 45.39  ? 16  PRO A C   1 
ATOM   62    O  O   . PRO A 1 16  ? 11.956  14.644  29.879  1.00 47.60  ? 16  PRO A O   1 
ATOM   63    C  CB  . PRO A 1 16  ? 12.991  12.186  31.658  1.00 62.59  ? 16  PRO A CB  1 
ATOM   64    C  CG  . PRO A 1 16  ? 11.675  11.674  32.303  1.00 61.11  ? 16  PRO A CG  1 
ATOM   65    C  CD  . PRO A 1 16  ? 11.182  12.793  33.200  1.00 56.94  ? 16  PRO A CD  1 
ATOM   66    N  N   . LEU A 1 17  ? 14.222  14.586  29.924  1.00 52.09  ? 17  LEU A N   1 
ATOM   67    C  CA  . LEU A 1 17  ? 14.469  14.978  28.536  1.00 52.90  ? 17  LEU A CA  1 
ATOM   68    C  C   . LEU A 1 17  ? 13.906  13.873  27.622  1.00 44.88  ? 17  LEU A C   1 
ATOM   69    O  O   . LEU A 1 17  ? 14.027  12.674  27.917  1.00 42.41  ? 17  LEU A O   1 
ATOM   70    C  CB  . LEU A 1 17  ? 15.964  15.281  28.323  1.00 63.43  ? 17  LEU A CB  1 
ATOM   71    C  CG  . LEU A 1 17  ? 16.563  16.499  29.072  1.00 78.28  ? 17  LEU A CG  1 
ATOM   72    C  CD1 . LEU A 1 17  ? 17.021  16.259  30.554  1.00 83.62  ? 17  LEU A CD1 1 
ATOM   73    C  CD2 . LEU A 1 17  ? 17.742  17.111  28.281  1.00 80.18  ? 17  LEU A CD2 1 
ATOM   74    N  N   . THR A 1 18  ? 13.110  14.299  26.626  1.00 37.44  ? 18  THR A N   1 
ATOM   75    C  CA  . THR A 1 18  ? 12.364  13.420  25.721  1.00 31.78  ? 18  THR A CA  1 
ATOM   76    C  C   . THR A 1 18  ? 12.660  13.925  24.317  1.00 28.84  ? 18  THR A C   1 
ATOM   77    O  O   . THR A 1 18  ? 12.840  15.110  24.121  1.00 33.69  ? 18  THR A O   1 
ATOM   78    C  CB  . THR A 1 18  ? 10.859  13.458  25.978  1.00 29.88  ? 18  THR A CB  1 
ATOM   79    O  OG1 . THR A 1 18  ? 10.427  14.817  26.029  1.00 33.98  ? 18  THR A OG1 1 
ATOM   80    C  CG2 . THR A 1 18  ? 10.480  12.771  27.265  1.00 32.13  ? 18  THR A CG2 1 
ATOM   81    N  N   . SER A 1 19  ? 12.732  13.041  23.333  1.00 29.71  ? 19  SER A N   1 
ATOM   82    C  CA  . SER A 1 19  ? 13.118  13.476  22.001  1.00 31.21  ? 19  SER A CA  1 
ATOM   83    C  C   . SER A 1 19  ? 11.910  13.684  21.052  1.00 29.67  ? 19  SER A C   1 
ATOM   84    O  O   . SER A 1 19  ? 12.040  14.191  19.946  1.00 23.88  ? 19  SER A O   1 
ATOM   85    C  CB  . SER A 1 19  ? 14.153  12.495  21.482  1.00 29.82  ? 19  SER A CB  1 
ATOM   86    O  OG  . SER A 1 19  ? 13.799  11.224  21.971  1.00 30.45  ? 19  SER A OG  1 
ATOM   87    N  N   . ALA A 1 20  ? 10.696  13.323  21.483  1.00 25.66  ? 20  ALA A N   1 
ATOM   88    C  CA  . ALA A 1 20  ? 9.530   13.474  20.633  1.00 25.28  ? 20  ALA A CA  1 
ATOM   89    C  C   . ALA A 1 20  ? 8.374   14.042  21.441  1.00 18.85  ? 20  ALA A C   1 
ATOM   90    O  O   . ALA A 1 20  ? 8.303   13.778  22.606  1.00 17.80  ? 20  ALA A O   1 
ATOM   91    C  CB  . ALA A 1 20  ? 9.181   12.145  20.048  1.00 24.24  ? 20  ALA A CB  1 
ATOM   92    N  N   . ALA A 1 21  ? 7.529   14.833  20.785  1.00 20.28  ? 21  ALA A N   1 
ATOM   93    C  CA  . ALA A 1 21  ? 6.367   15.431  21.404  1.00 19.72  ? 21  ALA A CA  1 
ATOM   94    C  C   . ALA A 1 21  ? 5.246   15.580  20.388  1.00 18.81  ? 21  ALA A C   1 
ATOM   95    O  O   . ALA A 1 21  ? 5.504   15.752  19.221  1.00 23.14  ? 21  ALA A O   1 
ATOM   96    C  CB  . ALA A 1 21  ? 6.726   16.748  21.995  1.00 17.46  ? 21  ALA A CB  1 
ATOM   97    N  N   . ILE A 1 22  ? 4.017   15.486  20.879  1.00 19.61  ? 22  ILE A N   1 
ATOM   98    C  CA  . ILE A 1 22  ? 2.847   15.956  20.158  1.00 18.04  ? 22  ILE A CA  1 
ATOM   99    C  C   . ILE A 1 22  ? 2.157   17.005  21.024  1.00 17.12  ? 22  ILE A C   1 
ATOM   100   O  O   . ILE A 1 22  ? 1.934   16.809  22.203  1.00 17.46  ? 22  ILE A O   1 
ATOM   101   C  CB  . ILE A 1 22  ? 1.891   14.820  19.793  1.00 20.88  ? 22  ILE A CB  1 
ATOM   102   C  CG1 . ILE A 1 22  ? 2.504   13.913  18.721  1.00 23.87  ? 22  ILE A CG1 1 
ATOM   103   C  CG2 . ILE A 1 22  ? 0.575   15.385  19.316  1.00 20.16  ? 22  ILE A CG2 1 
ATOM   104   C  CD1 . ILE A 1 22  ? 1.661   12.709  18.382  1.00 23.57  ? 22  ILE A CD1 1 
ATOM   105   N  N   . PHE A 1 23  ? 1.920   18.165  20.432  1.00 17.35  ? 23  PHE A N   1 
ATOM   106   C  CA  . PHE A 1 23  ? 1.124   19.201  21.046  1.00 19.00  ? 23  PHE A CA  1 
ATOM   107   C  C   . PHE A 1 23  ? -0.205  19.255  20.330  1.00 22.14  ? 23  PHE A C   1 
ATOM   108   O  O   . PHE A 1 23  ? -0.226  19.547  19.139  1.00 22.23  ? 23  PHE A O   1 
ATOM   109   C  CB  . PHE A 1 23  ? 1.775   20.562  20.900  1.00 18.54  ? 23  PHE A CB  1 
ATOM   110   C  CG  . PHE A 1 23  ? 3.169   20.633  21.476  1.00 20.53  ? 23  PHE A CG  1 
ATOM   111   C  CD1 . PHE A 1 23  ? 4.275   20.322  20.667  1.00 27.03  ? 23  PHE A CD1 1 
ATOM   112   C  CD2 . PHE A 1 23  ? 3.380   20.995  22.792  1.00 21.07  ? 23  PHE A CD2 1 
ATOM   113   C  CE1 . PHE A 1 23  ? 5.586   20.492  21.140  1.00 27.08  ? 23  PHE A CE1 1 
ATOM   114   C  CE2 . PHE A 1 23  ? 4.680   21.149  23.274  1.00 24.58  ? 23  PHE A CE2 1 
ATOM   115   C  CZ  . PHE A 1 23  ? 5.777   20.888  22.466  1.00 25.61  ? 23  PHE A CZ  1 
ATOM   116   N  N   . LEU A 1 24  ? -1.295  19.016  21.075  1.00 22.78  ? 24  LEU A N   1 
ATOM   117   C  CA  . LEU A 1 24  ? -2.653  19.033  20.577  1.00 22.34  ? 24  LEU A CA  1 
ATOM   118   C  C   . LEU A 1 24  ? -3.456  20.092  21.323  1.00 22.36  ? 24  LEU A C   1 
ATOM   119   O  O   . LEU A 1 24  ? -3.523  20.098  22.557  1.00 23.13  ? 24  LEU A O   1 
ATOM   120   C  CB  . LEU A 1 24  ? -3.043  17.628  20.927  1.00 24.91  ? 24  LEU A CB  1 
ATOM   121   C  CG  . LEU A 1 24  ? -4.183  17.008  20.142  1.00 37.11  ? 24  LEU A CG  1 
ATOM   122   C  CD1 . LEU A 1 24  ? -4.235  17.429  18.673  1.00 41.88  ? 24  LEU A CD1 1 
ATOM   123   C  CD2 . LEU A 1 24  ? -4.034  15.462  20.335  1.00 34.89  ? 24  LEU A CD2 1 
ATOM   124   N  N   . VAL A 1 25  ? -3.981  21.050  20.580  1.00 21.88  ? 25  VAL A N   1 
ATOM   125   C  CA  . VAL A 1 25  ? -4.855  22.089  21.098  1.00 22.70  ? 25  VAL A CA  1 
ATOM   126   C  C   . VAL A 1 25  ? -6.222  21.966  20.450  1.00 23.58  ? 25  VAL A C   1 
ATOM   127   O  O   . VAL A 1 25  ? -6.340  21.934  19.269  1.00 23.17  ? 25  VAL A O   1 
ATOM   128   C  CB  . VAL A 1 25  ? -4.296  23.487  20.866  1.00 25.18  ? 25  VAL A CB  1 
ATOM   129   C  CG1 . VAL A 1 25  ? -5.226  24.564  21.312  1.00 24.99  ? 25  VAL A CG1 1 
ATOM   130   C  CG2 . VAL A 1 25  ? -3.045  23.718  21.675  1.00 26.57  ? 25  VAL A CG2 1 
ATOM   131   N  N   . VAL A 1 26  ? -7.256  21.876  21.262  1.00 29.53  ? 26  VAL A N   1 
ATOM   132   C  CA  . VAL A 1 26  ? -8.627  21.719  20.802  1.00 25.35  ? 26  VAL A CA  1 
ATOM   133   C  C   . VAL A 1 26  ? -9.543  22.723  21.507  1.00 21.83  ? 26  VAL A C   1 
ATOM   134   O  O   . VAL A 1 26  ? -9.249  23.227  22.580  1.00 22.43  ? 26  VAL A O   1 
ATOM   135   C  CB  . VAL A 1 26  ? -9.120  20.274  21.027  1.00 27.40  ? 26  VAL A CB  1 
ATOM   136   C  CG1 . VAL A 1 26  ? -8.149  19.290  20.405  1.00 33.33  ? 26  VAL A CG1 1 
ATOM   137   C  CG2 . VAL A 1 26  ? -9.336  19.903  22.487  1.00 24.38  ? 26  VAL A CG2 1 
ATOM   138   N  N   . THR A 1 27  ? -10.669 23.025  20.854  1.00 24.27  ? 27  THR A N   1 
ATOM   139   C  CA  . THR A 1 27  ? -11.800 23.735  21.435  1.00 19.90  ? 27  THR A CA  1 
ATOM   140   C  C   . THR A 1 27  ? -12.946 22.763  21.671  1.00 20.62  ? 27  THR A C   1 
ATOM   141   O  O   . THR A 1 27  ? -13.078 21.709  21.027  1.00 20.63  ? 27  THR A O   1 
ATOM   142   C  CB  . THR A 1 27  ? -12.240 24.913  20.598  1.00 18.09  ? 27  THR A CB  1 
ATOM   143   O  OG1 . THR A 1 27  ? -12.514 24.406  19.302  1.00 18.20  ? 27  THR A OG1 1 
ATOM   144   C  CG2 . THR A 1 27  ? -11.234 26.034  20.639  1.00 18.28  ? 27  THR A CG2 1 
ATOM   145   N  N   . ILE A 1 28  ? -13.735 23.111  22.686  1.00 22.02  ? 28  ILE A N   1 
ATOM   146   C  CA  . ILE A 1 28  ? -14.808 22.225  23.150  1.00 26.28  ? 28  ILE A CA  1 
ATOM   147   C  C   . ILE A 1 28  ? -16.090 22.687  22.488  1.00 26.43  ? 28  ILE A C   1 
ATOM   148   O  O   . ILE A 1 28  ? -16.441 23.853  22.577  1.00 27.73  ? 28  ILE A O   1 
ATOM   149   C  CB  . ILE A 1 28  ? -14.951 22.228  24.688  1.00 29.36  ? 28  ILE A CB  1 
ATOM   150   C  CG1 . ILE A 1 28  ? -13.630 21.795  25.380  1.00 28.70  ? 28  ILE A CG1 1 
ATOM   151   C  CG2 . ILE A 1 28  ? -16.132 21.343  25.105  1.00 29.96  ? 28  ILE A CG2 1 
ATOM   152   C  CD1 . ILE A 1 28  ? -13.656 21.956  26.890  1.00 31.26  ? 28  ILE A CD1 1 
ATOM   153   N  N   . ASP A 1 29  ? -16.751 21.790  21.772  1.00 28.18  ? 29  ASP A N   1 
ATOM   154   C  CA  . ASP A 1 29  ? -17.949 22.164  21.048  1.00 33.90  ? 29  ASP A CA  1 
ATOM   155   C  C   . ASP A 1 29  ? -19.084 22.325  22.070  1.00 32.44  ? 29  ASP A C   1 
ATOM   156   O  O   . ASP A 1 29  ? -18.978 21.788  23.193  1.00 24.03  ? 29  ASP A O   1 
ATOM   157   C  CB  . ASP A 1 29  ? -18.247 21.079  20.017  1.00 39.28  ? 29  ASP A CB  1 
ATOM   158   C  CG  . ASP A 1 29  ? -17.242 20.846  18.895  1.00 36.81  ? 29  ASP A CG  1 
ATOM   159   O  OD1 . ASP A 1 29  ? -16.260 21.622  18.800  1.00 35.19  ? 29  ASP A OD1 1 
ATOM   160   O  OD2 . ASP A 1 29  ? -17.500 19.895  18.120  1.00 45.10  ? 29  ASP A OD2 1 
ATOM   161   N  N   . SER A 1 30  ? -20.154 23.036  21.653  1.00 32.07  ? 30  SER A N   1 
ATOM   162   C  CA  . SER A 1 30  ? -21.348 23.140  22.492  1.00 39.59  ? 30  SER A CA  1 
ATOM   163   C  C   . SER A 1 30  ? -21.899 21.763  22.786  1.00 31.89  ? 30  SER A C   1 
ATOM   164   O  O   . SER A 1 30  ? -22.099 21.001  21.856  1.00 37.43  ? 30  SER A O   1 
ATOM   165   C  CB  . SER A 1 30  ? -22.445 23.901  21.852  1.00 44.78  ? 30  SER A CB  1 
ATOM   166   O  OG  . SER A 1 30  ? -22.019 25.215  21.588  1.00 57.62  ? 30  SER A OG  1 
ATOM   167   N  N   . GLY A 1 31  ? -22.120 21.428  24.056  1.00 31.13  ? 31  GLY A N   1 
ATOM   168   C  CA  . GLY A 1 31  ? -22.631 20.093  24.354  1.00 30.66  ? 31  GLY A CA  1 
ATOM   169   C  C   . GLY A 1 31  ? -21.521 19.101  24.694  1.00 34.76  ? 31  GLY A C   1 
ATOM   170   O  O   . GLY A 1 31  ? -21.779 18.020  25.222  1.00 36.49  ? 31  GLY A O   1 
ATOM   171   N  N   . GLY A 1 32  ? -20.265 19.491  24.448  1.00 36.48  ? 32  GLY A N   1 
ATOM   172   C  CA  . GLY A 1 32  ? -19.140 18.583  24.596  1.00 41.64  ? 32  GLY A CA  1 
ATOM   173   C  C   . GLY A 1 32  ? -18.638 18.415  26.036  1.00 41.24  ? 32  GLY A C   1 
ATOM   174   O  O   . GLY A 1 32  ? -17.870 17.482  26.293  1.00 37.86  ? 32  GLY A O   1 
ATOM   175   N  N   . GLU A 1 33  ? -19.174 19.207  26.977  1.00 34.60  ? 33  GLU A N   1 
ATOM   176   C  CA  . GLU A 1 33  ? -18.627 19.298  28.314  1.00 27.52  ? 33  GLU A CA  1 
ATOM   177   C  C   . GLU A 1 33  ? -18.611 17.958  29.038  1.00 27.54  ? 33  GLU A C   1 
ATOM   178   O  O   . GLU A 1 33  ? -17.631 17.655  29.748  1.00 29.82  ? 33  GLU A O   1 
ATOM   179   C  CB  . GLU A 1 33  ? -19.343 20.365  29.117  1.00 26.76  ? 33  GLU A CB  1 
ATOM   180   C  CG  . GLU A 1 33  ? -19.152 21.805  28.610  1.00 30.69  ? 33  GLU A CG  1 
ATOM   181   C  CD  . GLU A 1 33  ? -20.038 22.300  27.456  1.00 31.81  ? 33  GLU A CD  1 
ATOM   182   O  OE1 . GLU A 1 33  ? -20.868 21.578  26.883  1.00 34.81  ? 33  GLU A OE1 1 
ATOM   183   O  OE2 . GLU A 1 33  ? -19.841 23.486  27.134  1.00 37.33  ? 33  GLU A OE2 1 
ATOM   184   N  N   . ASP A 1 34  ? -19.665 17.151  28.902  1.00 30.30  ? 34  ASP A N   1 
ATOM   185   C  CA  . ASP A 1 34  ? -19.681 15.910  29.675  1.00 31.62  ? 34  ASP A CA  1 
ATOM   186   C  C   . ASP A 1 34  ? -18.677 14.928  29.103  1.00 30.38  ? 34  ASP A C   1 
ATOM   187   O  O   . ASP A 1 34  ? -18.001 14.202  29.856  1.00 36.97  ? 34  ASP A O   1 
ATOM   188   C  CB  . ASP A 1 34  ? -21.019 15.195  29.778  1.00 37.94  ? 34  ASP A CB  1 
ATOM   189   C  CG  . ASP A 1 34  ? -22.101 15.957  30.518  1.00 51.85  ? 34  ASP A CG  1 
ATOM   190   O  OD1 . ASP A 1 34  ? -21.728 16.735  31.402  1.00 46.69  ? 34  ASP A OD1 1 
ATOM   191   O  OD2 . ASP A 1 34  ? -23.299 15.845  30.141  1.00 59.40  ? 34  ASP A OD2 1 
ATOM   192   N  N   . THR A 1 35  ? -18.588 14.882  27.778  1.00 29.25  ? 35  THR A N   1 
ATOM   193   C  CA  . THR A 1 35  ? -17.631 13.947  27.195  1.00 32.89  ? 35  THR A CA  1 
ATOM   194   C  C   . THR A 1 35  ? -16.223 14.281  27.685  1.00 31.97  ? 35  THR A C   1 
ATOM   195   O  O   . THR A 1 35  ? -15.443 13.399  28.043  1.00 27.27  ? 35  THR A O   1 
ATOM   196   C  CB  . THR A 1 35  ? -17.674 14.027  25.680  1.00 32.78  ? 35  THR A CB  1 
ATOM   197   O  OG1 . THR A 1 35  ? -18.954 13.522  25.385  1.00 34.39  ? 35  THR A OG1 1 
ATOM   198   C  CG2 . THR A 1 35  ? -16.675 13.091  25.039  1.00 33.55  ? 35  THR A CG2 1 
ATOM   199   N  N   . VAL A 1 36  ? -15.937 15.590  27.676  1.00 29.66  ? 36  VAL A N   1 
ATOM   200   C  CA  . VAL A 1 36  ? -14.649 16.092  28.100  1.00 26.54  ? 36  VAL A CA  1 
ATOM   201   C  C   . VAL A 1 36  ? -14.370 15.671  29.533  1.00 24.25  ? 36  VAL A C   1 
ATOM   202   O  O   . VAL A 1 36  ? -13.322 15.139  29.804  1.00 25.05  ? 36  VAL A O   1 
ATOM   203   C  CB  . VAL A 1 36  ? -14.516 17.608  27.885  1.00 23.36  ? 36  VAL A CB  1 
ATOM   204   C  CG1 . VAL A 1 36  ? -13.234 18.137  28.538  1.00 25.73  ? 36  VAL A CG1 1 
ATOM   205   C  CG2 . VAL A 1 36  ? -14.526 17.925  26.402  1.00 23.27  ? 36  VAL A CG2 1 
ATOM   206   N  N   . ARG A 1 37  ? -15.292 15.912  30.446  1.00 27.79  ? 37  ARG A N   1 
ATOM   207   C  CA  . ARG A 1 37  ? -15.060 15.577  31.842  1.00 28.85  ? 37  ARG A CA  1 
ATOM   208   C  C   . ARG A 1 37  ? -14.756 14.106  32.039  1.00 28.84  ? 37  ARG A C   1 
ATOM   209   O  O   . ARG A 1 37  ? -13.918 13.767  32.870  1.00 31.34  ? 37  ARG A O   1 
ATOM   210   C  CB  . ARG A 1 37  ? -16.292 15.866  32.692  1.00 38.13  ? 37  ARG A CB  1 
ATOM   211   C  CG  . ARG A 1 37  ? -16.411 17.270  33.238  1.00 49.25  ? 37  ARG A CG  1 
ATOM   212   C  CD  . ARG A 1 37  ? -17.472 17.299  34.354  1.00 51.49  ? 37  ARG A CD  1 
ATOM   213   N  NE  . ARG A 1 37  ? -18.088 18.605  34.113  1.00 55.74  ? 37  ARG A NE  1 
ATOM   214   C  CZ  . ARG A 1 37  ? -19.009 18.990  33.227  1.00 45.95  ? 37  ARG A CZ  1 
ATOM   215   N  NH1 . ARG A 1 37  ? -19.135 20.276  32.978  1.00 60.26  ? 37  ARG A NH1 1 
ATOM   216   N  NH2 . ARG A 1 37  ? -19.814 18.175  32.601  1.00 47.86  ? 37  ARG A NH2 1 
ATOM   217   N  N   . ASP A 1 38  ? -15.444 13.225  31.309  1.00 33.82  ? 38  ASP A N   1 
ATOM   218   C  CA  . ASP A 1 38  ? -15.171 11.792  31.446  1.00 36.84  ? 38  ASP A CA  1 
ATOM   219   C  C   . ASP A 1 38  ? -13.751 11.450  31.009  1.00 34.54  ? 38  ASP A C   1 
ATOM   220   O  O   . ASP A 1 38  ? -13.069 10.663  31.643  1.00 32.88  ? 38  ASP A O   1 
ATOM   221   C  CB  . ASP A 1 38  ? -16.088 10.890  30.636  1.00 50.07  ? 38  ASP A CB  1 
ATOM   222   C  CG  . ASP A 1 38  ? -17.485 10.700  31.237  1.00 61.99  ? 38  ASP A CG  1 
ATOM   223   O  OD1 . ASP A 1 38  ? -17.661 10.898  32.477  1.00 54.83  ? 38  ASP A OD1 1 
ATOM   224   O  OD2 . ASP A 1 38  ? -18.439 10.462  30.448  1.00 69.47  ? 38  ASP A OD2 1 
ATOM   225   N  N   . LEU A 1 39  ? -13.322 12.031  29.890  1.00 30.67  ? 39  LEU A N   1 
ATOM   226   C  CA  . LEU A 1 39  ? -11.969 11.847  29.385  1.00 27.35  ? 39  LEU A CA  1 
ATOM   227   C  C   . LEU A 1 39  ? -10.958 12.327  30.413  1.00 28.61  ? 39  LEU A C   1 
ATOM   228   O  O   . LEU A 1 39  ? -9.978  11.611  30.639  1.00 26.75  ? 39  LEU A O   1 
ATOM   229   C  CB  . LEU A 1 39  ? -11.835 12.559  28.036  1.00 28.22  ? 39  LEU A CB  1 
ATOM   230   C  CG  . LEU A 1 39  ? -10.574 12.428  27.190  1.00 26.49  ? 39  LEU A CG  1 
ATOM   231   C  CD1 . LEU A 1 39  ? -9.616  13.439  27.696  1.00 31.10  ? 39  LEU A CD1 1 
ATOM   232   C  CD2 . LEU A 1 39  ? -9.986  11.020  27.196  1.00 27.01  ? 39  LEU A CD2 1 
ATOM   233   N  N   . LEU A 1 40  ? -11.148 13.522  31.018  1.00 25.98  ? 40  LEU A N   1 
ATOM   234   C  CA  . LEU A 1 40  ? -10.139 14.037  31.935  1.00 25.63  ? 40  LEU A CA  1 
ATOM   235   C  C   . LEU A 1 40  ? -9.908  13.039  33.073  1.00 29.82  ? 40  LEU A C   1 
ATOM   236   O  O   . LEU A 1 40  ? -8.828  12.910  33.629  1.00 29.61  ? 40  LEU A O   1 
ATOM   237   C  CB  . LEU A 1 40  ? -10.587 15.385  32.459  1.00 27.26  ? 40  LEU A CB  1 
ATOM   238   C  CG  . LEU A 1 40  ? -10.620 16.535  31.448  1.00 32.74  ? 40  LEU A CG  1 
ATOM   239   C  CD1 . LEU A 1 40  ? -11.083 17.849  32.052  1.00 31.55  ? 40  LEU A CD1 1 
ATOM   240   C  CD2 . LEU A 1 40  ? -9.267  16.741  30.867  1.00 37.21  ? 40  LEU A CD2 1 
ATOM   241   N  N   . SER A 1 41  ? -10.953 12.328  33.473  1.00 31.07  ? 41  SER A N   1 
ATOM   242   C  CA  . SER A 1 41  ? -10.819 11.469  34.626  1.00 31.67  ? 41  SER A CA  1 
ATOM   243   C  C   . SER A 1 41  ? -10.150 10.158  34.217  1.00 30.78  ? 41  SER A C   1 
ATOM   244   O  O   . SER A 1 41  ? -9.796  9.339   35.047  1.00 29.69  ? 41  SER A O   1 
ATOM   245   C  CB  . SER A 1 41  ? -12.179 11.226  35.295  1.00 34.04  ? 41  SER A CB  1 
ATOM   246   O  OG  . SER A 1 41  ? -13.010 10.424  34.470  1.00 39.29  ? 41  SER A OG  1 
ATOM   247   N  N   . ASP A 1 42  ? -9.962  9.935   32.926  1.00 35.50  ? 42  ASP A N   1 
ATOM   248   C  CA  . ASP A 1 42  ? -9.358  8.702   32.450  1.00 34.71  ? 42  ASP A CA  1 
ATOM   249   C  C   . ASP A 1 42  ? -7.970  8.902   31.857  1.00 27.92  ? 42  ASP A C   1 
ATOM   250   O  O   . ASP A 1 42  ? -7.330  7.920   31.501  1.00 30.53  ? 42  ASP A O   1 
ATOM   251   C  CB  . ASP A 1 42  ? -10.231 8.054   31.394  1.00 40.22  ? 42  ASP A CB  1 
ATOM   252   C  CG  . ASP A 1 42  ? -11.321 7.148   31.948  1.00 42.03  ? 42  ASP A CG  1 
ATOM   253   O  OD1 . ASP A 1 42  ? -11.176 6.685   33.092  1.00 45.08  ? 42  ASP A OD1 1 
ATOM   254   O  OD2 . ASP A 1 42  ? -12.326 6.980   31.242  1.00 42.76  ? 42  ASP A OD2 1 
ATOM   255   N  N   . VAL A 1 43  ? -7.525  10.146  31.694  1.00 25.46  ? 43  VAL A N   1 
ATOM   256   C  CA  . VAL A 1 43  ? -6.354  10.395  30.882  1.00 26.18  ? 43  VAL A CA  1 
ATOM   257   C  C   . VAL A 1 43  ? -5.105  9.727   31.497  1.00 25.86  ? 43  VAL A C   1 
ATOM   258   O  O   . VAL A 1 43  ? -4.325  9.097   30.785  1.00 23.86  ? 43  VAL A O   1 
ATOM   259   C  CB  . VAL A 1 43  ? -6.218  11.887  30.608  1.00 27.72  ? 43  VAL A CB  1 
ATOM   260   C  CG1 . VAL A 1 43  ? -5.715  12.557  31.828  1.00 35.89  ? 43  VAL A CG1 1 
ATOM   261   C  CG2 . VAL A 1 43  ? -5.207  12.182  29.553  1.00 35.25  ? 43  VAL A CG2 1 
ATOM   262   N  N   . ALA A 1 44  ? -4.995  9.700   32.836  1.00 26.89  ? 44  ALA A N   1 
ATOM   263   C  CA  . ALA A 1 44  ? -3.871  9.036   33.497  1.00 23.57  ? 44  ALA A CA  1 
ATOM   264   C  C   . ALA A 1 44  ? -3.879  7.542   33.241  1.00 27.72  ? 44  ALA A C   1 
ATOM   265   O  O   . ALA A 1 44  ? -2.799  6.955   33.092  1.00 30.02  ? 44  ALA A O   1 
ATOM   266   C  CB  . ALA A 1 44  ? -3.922  9.307   34.963  1.00 22.61  ? 44  ALA A CB  1 
ATOM   267   N  N   . SER A 1 45  ? -5.075  6.926   33.172  1.00 28.84  ? 45  SER A N   1 
ATOM   268   C  CA  . SER A 1 45  ? -5.080  5.487   32.980  1.00 30.29  ? 45  SER A CA  1 
ATOM   269   C  C   . SER A 1 45  ? -4.758  5.121   31.532  1.00 27.11  ? 45  SER A C   1 
ATOM   270   O  O   . SER A 1 45  ? -4.092  4.088   31.319  1.00 25.94  ? 45  SER A O   1 
ATOM   271   C  CB  . SER A 1 45  ? -6.319  4.829   33.513  1.00 32.23  ? 45  SER A CB  1 
ATOM   272   O  OG  . SER A 1 45  ? -7.394  5.268   32.718  1.00 38.74  ? 45  SER A OG  1 
ATOM   273   N  N   . LEU A 1 46  ? -5.119  6.004   30.578  1.00 23.31  ? 46  LEU A N   1 
ATOM   274   C  CA  . LEU A 1 46  ? -4.721  5.772   29.210  1.00 25.49  ? 46  LEU A CA  1 
ATOM   275   C  C   . LEU A 1 46  ? -3.194  5.893   29.062  1.00 24.85  ? 46  LEU A C   1 
ATOM   276   O  O   . LEU A 1 46  ? -2.582  5.130   28.324  1.00 26.05  ? 46  LEU A O   1 
ATOM   277   C  CB  . LEU A 1 46  ? -5.468  6.731   28.298  1.00 25.50  ? 46  LEU A CB  1 
ATOM   278   C  CG  . LEU A 1 46  ? -6.959  6.517   28.191  1.00 27.16  ? 46  LEU A CG  1 
ATOM   279   C  CD1 . LEU A 1 46  ? -7.619  7.646   27.457  1.00 31.87  ? 46  LEU A CD1 1 
ATOM   280   C  CD2 . LEU A 1 46  ? -7.158  5.246   27.434  1.00 27.57  ? 46  LEU A CD2 1 
ATOM   281   N  N   . GLU A 1 47  ? -2.604  6.870   29.753  1.00 27.17  ? 47  GLU A N   1 
ATOM   282   C  CA  . GLU A 1 47  ? -1.181  7.087   29.729  1.00 27.88  ? 47  GLU A CA  1 
ATOM   283   C  C   . GLU A 1 47  ? -0.481  5.807   30.166  1.00 27.81  ? 47  GLU A C   1 
ATOM   284   O  O   . GLU A 1 47  ? 0.420   5.337   29.478  1.00 23.83  ? 47  GLU A O   1 
ATOM   285   C  CB  . GLU A 1 47  ? -0.927  8.332   30.579  1.00 31.52  ? 47  GLU A CB  1 
ATOM   286   C  CG  . GLU A 1 47  ? 0.548   8.667   30.730  1.00 34.67  ? 47  GLU A CG  1 
ATOM   287   C  CD  . GLU A 1 47  ? 0.833   9.692   31.807  1.00 30.42  ? 47  GLU A CD  1 
ATOM   288   O  OE1 . GLU A 1 47  ? 0.775   10.868  31.693  1.00 33.67  ? 47  GLU A OE1 1 
ATOM   289   O  OE2 . GLU A 1 47  ? 1.130   9.289   32.879  1.00 48.41  ? 47  GLU A OE2 1 
ATOM   290   N  N   . ARG A 1 48  ? -0.932  5.179   31.257  1.00 29.42  ? 48  ARG A N   1 
ATOM   291   C  CA  . ARG A 1 48  ? -0.354  3.890   31.685  1.00 29.77  ? 48  ARG A CA  1 
ATOM   292   C  C   . ARG A 1 48  ? -0.558  2.774   30.658  1.00 27.25  ? 48  ARG A C   1 
ATOM   293   O  O   . ARG A 1 48  ? 0.336   2.000   30.403  1.00 27.52  ? 48  ARG A O   1 
ATOM   294   C  CB  . ARG A 1 48  ? -0.941  3.368   33.015  1.00 31.51  ? 48  ARG A CB  1 
ATOM   295   C  CG  . ARG A 1 48  ? -0.533  4.331   34.118  1.00 42.04  ? 48  ARG A CG  1 
ATOM   296   C  CD  . ARG A 1 48  ? -0.605  3.812   35.541  1.00 52.24  ? 48  ARG A CD  1 
ATOM   297   N  NE  . ARG A 1 48  ? -1.979  3.368   35.821  1.00 58.30  ? 48  ARG A NE  1 
ATOM   298   C  CZ  . ARG A 1 48  ? -3.021  4.169   36.167  1.00 52.51  ? 48  ARG A CZ  1 
ATOM   299   N  NH1 . ARG A 1 48  ? -2.874  5.475   36.365  1.00 43.50  ? 48  ARG A NH1 1 
ATOM   300   N  NH2 . ARG A 1 48  ? -4.250  3.669   36.218  1.00 54.46  ? 48  ARG A NH2 1 
ATOM   301   N  N   . ALA A 1 49  ? -1.758  2.631   30.107  1.00 27.17  ? 49  ALA A N   1 
ATOM   302   C  CA  . ALA A 1 49  ? -2.020  1.533   29.202  1.00 29.22  ? 49  ALA A CA  1 
ATOM   303   C  C   . ALA A 1 49  ? -1.099  1.575   27.990  1.00 31.02  ? 49  ALA A C   1 
ATOM   304   O  O   . ALA A 1 49  ? -0.523  0.539   27.623  1.00 34.30  ? 49  ALA A O   1 
ATOM   305   C  CB  . ALA A 1 49  ? -3.447  1.579   28.770  1.00 29.85  ? 49  ALA A CB  1 
ATOM   306   N  N   . VAL A 1 50  ? -0.972  2.777   27.378  1.00 29.25  ? 50  VAL A N   1 
ATOM   307   C  CA  . VAL A 1 50  ? -0.126  2.939   26.206  1.00 25.67  ? 50  VAL A CA  1 
ATOM   308   C  C   . VAL A 1 50  ? 1.344   2.849   26.589  1.00 27.41  ? 50  VAL A C   1 
ATOM   309   O  O   . VAL A 1 50  ? 2.133   2.219   25.875  1.00 31.74  ? 50  VAL A O   1 
ATOM   310   C  CB  . VAL A 1 50  ? -0.379  4.247   25.470  1.00 27.82  ? 50  VAL A CB  1 
ATOM   311   C  CG1 . VAL A 1 50  ? 0.590   4.463   24.317  1.00 31.69  ? 50  VAL A CG1 1 
ATOM   312   C  CG2 . VAL A 1 50  ? -1.807  4.339   24.943  1.00 30.75  ? 50  VAL A CG2 1 
ATOM   313   N  N   . GLY A 1 51  ? 1.709   3.407   27.743  1.00 28.01  ? 51  GLY A N   1 
ATOM   314   C  CA  . GLY A 1 51  ? 3.107   3.569   28.111  1.00 30.53  ? 51  GLY A CA  1 
ATOM   315   C  C   . GLY A 1 51  ? 3.744   2.339   28.777  1.00 35.44  ? 51  GLY A C   1 
ATOM   316   O  O   . GLY A 1 51  ? 4.924   2.091   28.583  1.00 32.43  ? 51  GLY A O   1 
ATOM   317   N  N   . PHE A 1 52  ? 2.998   1.590   29.593  1.00 36.58  ? 52  PHE A N   1 
ATOM   318   C  CA  . PHE A 1 52  ? 3.615   0.601   30.475  1.00 36.62  ? 52  PHE A CA  1 
ATOM   319   C  C   . PHE A 1 52  ? 4.400   -0.446  29.674  1.00 36.07  ? 52  PHE A C   1 
ATOM   320   O  O   . PHE A 1 52  ? 5.506   -0.784  30.070  1.00 38.69  ? 52  PHE A O   1 
ATOM   321   C  CB  . PHE A 1 52  ? 2.597   -0.065  31.402  1.00 32.49  ? 52  PHE A CB  1 
ATOM   322   C  CG  . PHE A 1 52  ? 3.318   -1.081  32.261  1.00 28.80  ? 52  PHE A CG  1 
ATOM   323   C  CD1 . PHE A 1 52  ? 3.998   -0.665  33.378  1.00 31.63  ? 52  PHE A CD1 1 
ATOM   324   C  CD2 . PHE A 1 52  ? 3.350   -2.430  31.911  1.00 27.03  ? 52  PHE A CD2 1 
ATOM   325   C  CE1 . PHE A 1 52  ? 4.702   -1.585  34.126  1.00 36.23  ? 52  PHE A CE1 1 
ATOM   326   C  CE2 . PHE A 1 52  ? 4.001   -3.379  32.670  1.00 30.23  ? 52  PHE A CE2 1 
ATOM   327   C  CZ  . PHE A 1 52  ? 4.677   -2.957  33.778  1.00 36.79  ? 52  PHE A CZ  1 
ATOM   328   N  N   . ARG A 1 53  ? 3.885   -0.928  28.540  1.00 42.19  ? 53  ARG A N   1 
ATOM   329   C  CA  . ARG A 1 53  ? 4.586   -1.967  27.806  1.00 43.12  ? 53  ARG A CA  1 
ATOM   330   C  C   . ARG A 1 53  ? 5.902   -1.515  27.171  1.00 41.82  ? 53  ARG A C   1 
ATOM   331   O  O   . ARG A 1 53  ? 6.650   -2.357  26.709  1.00 47.04  ? 53  ARG A O   1 
ATOM   332   C  CB  . ARG A 1 53  ? 3.668   -2.554  26.732  1.00 50.36  ? 53  ARG A CB  1 
ATOM   333   C  CG  . ARG A 1 53  ? 3.114   -1.742  25.577  1.00 51.34  ? 53  ARG A CG  1 
ATOM   334   C  CD  . ARG A 1 53  ? 2.473   -2.805  24.605  1.00 50.58  ? 53  ARG A CD  1 
ATOM   335   N  NE  . ARG A 1 53  ? 1.578   -2.213  23.601  1.00 49.50  ? 53  ARG A NE  1 
ATOM   336   C  CZ  . ARG A 1 53  ? 0.659   -1.362  24.000  1.00 57.10  ? 53  ARG A CZ  1 
ATOM   337   N  NH1 . ARG A 1 53  ? 0.511   -1.099  25.293  1.00 66.22  ? 53  ARG A NH1 1 
ATOM   338   N  NH2 . ARG A 1 53  ? -0.117  -0.778  23.125  1.00 57.71  ? 53  ARG A NH2 1 
ATOM   339   N  N   . ALA A 1 54  ? 6.184   -0.209  27.114  1.00 41.14  ? 54  ALA A N   1 
ATOM   340   C  CA  . ALA A 1 54  ? 7.478   0.282   26.641  1.00 37.39  ? 54  ALA A CA  1 
ATOM   341   C  C   . ALA A 1 54  ? 8.372   0.798   27.778  1.00 45.30  ? 54  ALA A C   1 
ATOM   342   O  O   . ALA A 1 54  ? 9.252   1.578   27.495  1.00 45.87  ? 54  ALA A O   1 
ATOM   343   C  CB  . ALA A 1 54  ? 7.229   1.395   25.654  1.00 39.10  ? 54  ALA A CB  1 
ATOM   344   N  N   . GLN A 1 55  ? 8.160   0.422   29.056  1.00 61.89  ? 55  GLN A N   1 
ATOM   345   C  CA  . GLN A 1 55  ? 8.969   0.896   30.194  1.00 69.55  ? 55  GLN A CA  1 
ATOM   346   C  C   . GLN A 1 55  ? 10.286  0.133   30.212  1.00 67.30  ? 55  GLN A C   1 
ATOM   347   O  O   . GLN A 1 55  ? 10.265  -0.966  29.689  1.00 62.11  ? 55  GLN A O   1 
ATOM   348   C  CB  . GLN A 1 55  ? 8.347   0.740   31.589  1.00 79.69  ? 55  GLN A CB  1 
ATOM   349   C  CG  . GLN A 1 55  ? 7.276   1.787   31.910  1.00 83.36  ? 55  GLN A CG  1 
ATOM   350   C  CD  . GLN A 1 55  ? 7.730   3.245   31.834  1.00 90.96  ? 55  GLN A CD  1 
ATOM   351   O  OE1 . GLN A 1 55  ? 8.484   3.733   30.965  1.00 77.17  ? 55  GLN A OE1 1 
ATOM   352   N  NE2 . GLN A 1 55  ? 7.230   4.002   32.793  1.00 96.10  ? 55  GLN A NE2 1 
ATOM   353   N  N   . PRO A 1 56  ? 11.442  0.687   30.688  1.00 78.46  ? 56  PRO A N   1 
ATOM   354   C  CA  . PRO A 1 56  ? 11.553  2.060   31.206  1.00 77.71  ? 56  PRO A CA  1 
ATOM   355   C  C   . PRO A 1 56  ? 12.030  3.157   30.211  1.00 68.54  ? 56  PRO A C   1 
ATOM   356   O  O   . PRO A 1 56  ? 11.978  4.361   30.494  1.00 60.38  ? 56  PRO A O   1 
ATOM   357   C  CB  . PRO A 1 56  ? 12.561  1.806   32.386  1.00 62.86  ? 56  PRO A CB  1 
ATOM   358   C  CG  . PRO A 1 56  ? 13.373  0.582   31.987  1.00 63.91  ? 56  PRO A CG  1 
ATOM   359   C  CD  . PRO A 1 56  ? 12.768  0.034   30.695  1.00 75.20  ? 56  PRO A CD  1 
ATOM   360   N  N   . ASP A 1 57  ? 12.382  2.751   28.986  1.00 51.86  ? 57  ASP A N   1 
ATOM   361   C  CA  . ASP A 1 57  ? 12.855  3.652   27.939  1.00 65.62  ? 57  ASP A CA  1 
ATOM   362   C  C   . ASP A 1 57  ? 11.813  4.648   27.429  1.00 58.01  ? 57  ASP A C   1 
ATOM   363   O  O   . ASP A 1 57  ? 12.178  5.720   26.958  1.00 47.83  ? 57  ASP A O   1 
ATOM   364   C  CB  . ASP A 1 57  ? 13.238  2.846   26.710  1.00 78.06  ? 57  ASP A CB  1 
ATOM   365   C  CG  . ASP A 1 57  ? 14.087  1.659   27.105  1.00 86.57  ? 57  ASP A CG  1 
ATOM   366   O  OD1 . ASP A 1 57  ? 15.049  1.925   27.891  1.00 69.56  ? 57  ASP A OD1 1 
ATOM   367   O  OD2 . ASP A 1 57  ? 13.705  0.523   26.715  1.00 84.11  ? 57  ASP A OD2 1 
ATOM   368   N  N   . GLY A 1 58  ? 10.529  4.268   27.432  1.00 45.93  ? 58  GLY A N   1 
ATOM   369   C  CA  . GLY A 1 58  ? 9.534   5.023   26.686  1.00 38.56  ? 58  GLY A CA  1 
ATOM   370   C  C   . GLY A 1 58  ? 9.315   6.446   27.218  1.00 29.58  ? 58  GLY A C   1 
ATOM   371   O  O   . GLY A 1 58  ? 9.114   7.346   26.416  1.00 28.32  ? 58  GLY A O   1 
ATOM   372   N  N   . ARG A 1 59  ? 9.347   6.631   28.549  1.00 27.93  ? 59  ARG A N   1 
ATOM   373   C  CA  . ARG A 1 59  ? 9.153   7.911   29.192  1.00 30.22  ? 59  ARG A CA  1 
ATOM   374   C  C   . ARG A 1 59  ? 7.963   8.700   28.627  1.00 29.48  ? 59  ARG A C   1 
ATOM   375   O  O   . ARG A 1 59  ? 8.031   9.914   28.455  1.00 29.69  ? 59  ARG A O   1 
ATOM   376   C  CB  . ARG A 1 59  ? 10.422  8.702   28.960  1.00 37.18  ? 59  ARG A CB  1 
ATOM   377   C  CG  . ARG A 1 59  ? 11.739  8.248   29.550  1.00 48.93  ? 59  ARG A CG  1 
ATOM   378   C  CD  . ARG A 1 59  ? 12.718  9.344   29.034  1.00 56.60  ? 59  ARG A CD  1 
ATOM   379   N  NE  . ARG A 1 59  ? 14.062  9.329   29.609  1.00 60.28  ? 59  ARG A NE  1 
ATOM   380   N  N   . LEU A 1 60  ? 6.846   8.010   28.345  1.00 27.43  ? 60  LEU A N   1 
ATOM   381   C  CA  . LEU A 1 60  ? 5.599   8.614   27.885  1.00 24.89  ? 60  LEU A CA  1 
ATOM   382   C  C   . LEU A 1 60  ? 4.904   9.376   29.008  1.00 28.07  ? 60  LEU A C   1 
ATOM   383   O  O   . LEU A 1 60  ? 4.760   8.874   30.110  1.00 33.06  ? 60  LEU A O   1 
ATOM   384   C  CB  . LEU A 1 60  ? 4.670   7.526   27.380  1.00 24.98  ? 60  LEU A CB  1 
ATOM   385   C  CG  . LEU A 1 60  ? 3.284   8.016   26.948  1.00 27.66  ? 60  LEU A CG  1 
ATOM   386   C  CD1 . LEU A 1 60  ? 3.310   8.988   25.700  1.00 27.51  ? 60  LEU A CD1 1 
ATOM   387   C  CD2 . LEU A 1 60  ? 2.440   6.786   26.664  1.00 28.48  ? 60  LEU A CD2 1 
ATOM   388   N  N   . SER A 1 61  ? 4.515   10.601  28.747  1.00 24.03  ? 61  SER A N   1 
ATOM   389   C  CA  . SER A 1 61  ? 3.730   11.367  29.700  1.00 26.67  ? 61  SER A CA  1 
ATOM   390   C  C   . SER A 1 61  ? 2.837   12.311  28.913  1.00 24.85  ? 61  SER A C   1 
ATOM   391   O  O   . SER A 1 61  ? 3.134   12.670  27.775  1.00 24.92  ? 61  SER A O   1 
ATOM   392   C  CB  . SER A 1 61  ? 4.586   12.170  30.692  1.00 27.67  ? 61  SER A CB  1 
ATOM   393   O  OG  . SER A 1 61  ? 5.365   13.179  30.057  1.00 31.41  ? 61  SER A OG  1 
ATOM   394   N  N   . CYS A 1 62  ? 1.773   12.745  29.572  1.00 23.17  ? 62  CYS A N   1 
ATOM   395   C  CA  . CYS A 1 62  ? 0.766   13.588  28.957  1.00 22.11  ? 62  CYS A CA  1 
ATOM   396   C  C   . CYS A 1 62  ? 0.420   14.619  29.995  1.00 23.08  ? 62  CYS A C   1 
ATOM   397   O  O   . CYS A 1 62  ? 0.049   14.253  31.097  1.00 24.35  ? 62  CYS A O   1 
ATOM   398   C  CB  . CYS A 1 62  ? -0.518  12.855  28.589  1.00 23.57  ? 62  CYS A CB  1 
ATOM   399   S  SG  . CYS A 1 62  ? -1.760  13.986  27.916  1.00 25.86  ? 62  CYS A SG  1 
ATOM   400   N  N   . VAL A 1 63  ? 0.607   15.893  29.697  1.00 20.46  ? 63  VAL A N   1 
ATOM   401   C  CA  . VAL A 1 63  ? 0.140   16.890  30.610  1.00 18.07  ? 63  VAL A CA  1 
ATOM   402   C  C   . VAL A 1 63  ? -1.065  17.537  29.968  1.00 20.71  ? 63  VAL A C   1 
ATOM   403   O  O   . VAL A 1 63  ? -1.007  17.975  28.812  1.00 21.96  ? 63  VAL A O   1 
ATOM   404   C  CB  . VAL A 1 63  ? 1.232   17.897  30.917  1.00 19.81  ? 63  VAL A CB  1 
ATOM   405   C  CG1 . VAL A 1 63  ? 0.702   19.039  31.758  1.00 21.45  ? 63  VAL A CG1 1 
ATOM   406   C  CG2 . VAL A 1 63  ? 2.388   17.252  31.667  1.00 23.53  ? 63  VAL A CG2 1 
ATOM   407   N  N   . THR A 1 64  ? -2.145  17.611  30.745  1.00 23.38  ? 64  THR A N   1 
ATOM   408   C  CA  . THR A 1 64  ? -3.405  18.143  30.271  1.00 22.99  ? 64  THR A CA  1 
ATOM   409   C  C   . THR A 1 64  ? -3.627  19.520  30.913  1.00 22.50  ? 64  THR A C   1 
ATOM   410   O  O   . THR A 1 64  ? -3.501  19.705  32.110  1.00 21.33  ? 64  THR A O   1 
ATOM   411   C  CB  . THR A 1 64  ? -4.532  17.203  30.688  1.00 24.35  ? 64  THR A CB  1 
ATOM   412   O  OG1 . THR A 1 64  ? -4.233  15.944  30.137  1.00 22.78  ? 64  THR A OG1 1 
ATOM   413   C  CG2 . THR A 1 64  ? -5.864  17.669  30.143  1.00 25.49  ? 64  THR A CG2 1 
ATOM   414   N  N   . GLY A 1 65  ? -3.980  20.464  30.073  1.00 22.20  ? 65  GLY A N   1 
ATOM   415   C  CA  . GLY A 1 65  ? -4.267  21.815  30.500  1.00 25.16  ? 65  GLY A CA  1 
ATOM   416   C  C   . GLY A 1 65  ? -5.643  22.309  29.989  1.00 22.69  ? 65  GLY A C   1 
ATOM   417   O  O   . GLY A 1 65  ? -6.159  21.903  28.945  1.00 19.74  ? 65  GLY A O   1 
ATOM   418   N  N   . ILE A 1 66  ? -6.191  23.268  30.764  1.00 23.88  ? 66  ILE A N   1 
ATOM   419   C  CA  . ILE A 1 66  ? -7.527  23.767  30.595  1.00 22.30  ? 66  ILE A CA  1 
ATOM   420   C  C   . ILE A 1 66  ? -7.455  25.282  30.516  1.00 23.75  ? 66  ILE A C   1 
ATOM   421   O  O   . ILE A 1 66  ? -6.811  25.903  31.356  1.00 24.50  ? 66  ILE A O   1 
ATOM   422   C  CB  . ILE A 1 66  ? -8.409  23.232  31.742  1.00 24.16  ? 66  ILE A CB  1 
ATOM   423   C  CG1 . ILE A 1 66  ? -8.479  21.705  31.674  1.00 24.87  ? 66  ILE A CG1 1 
ATOM   424   C  CG2 . ILE A 1 66  ? -9.808  23.812  31.649  1.00 22.92  ? 66  ILE A CG2 1 
ATOM   425   C  CD1 . ILE A 1 66  ? -8.765  21.056  32.978  1.00 27.24  ? 66  ILE A CD1 1 
ATOM   426   N  N   . GLY A 1 67  ? -8.085  25.846  29.478  1.00 21.76  ? 67  GLY A N   1 
ATOM   427   C  CA  . GLY A 1 67  ? -8.119  27.275  29.321  1.00 21.54  ? 67  GLY A CA  1 
ATOM   428   C  C   . GLY A 1 67  ? -9.156  27.936  30.220  1.00 23.45  ? 67  GLY A C   1 
ATOM   429   O  O   . GLY A 1 67  ? -10.008 27.280  30.822  1.00 23.65  ? 67  GLY A O   1 
ATOM   430   N  N   . SER A 1 68  ? -9.043  29.272  30.273  1.00 25.53  ? 68  SER A N   1 
ATOM   431   C  CA  . SER A 1 68  ? -9.861  30.113  31.123  1.00 24.17  ? 68  SER A CA  1 
ATOM   432   C  C   . SER A 1 68  ? -11.351 29.978  30.811  1.00 26.31  ? 68  SER A C   1 
ATOM   433   O  O   . SER A 1 68  ? -12.130 29.654  31.695  1.00 28.76  ? 68  SER A O   1 
ATOM   434   C  CB  . SER A 1 68  ? -9.433  31.524  30.966  1.00 29.40  ? 68  SER A CB  1 
ATOM   435   O  OG  . SER A 1 68  ? -9.991  32.329  31.977  1.00 27.63  ? 68  SER A OG  1 
ATOM   436   N  N   . GLU A 1 69  ? -11.777 30.210  29.573  1.00 27.13  ? 69  GLU A N   1 
ATOM   437   C  CA  . GLU A 1 69  ? -13.186 30.156  29.247  1.00 26.46  ? 69  GLU A CA  1 
ATOM   438   C  C   . GLU A 1 69  ? -13.724 28.742  29.432  1.00 30.71  ? 69  GLU A C   1 
ATOM   439   O  O   . GLU A 1 69  ? -14.842 28.567  29.885  1.00 32.32  ? 69  GLU A O   1 
ATOM   440   C  CB  . GLU A 1 69  ? -13.367 30.541  27.793  1.00 32.74  ? 69  GLU A CB  1 
ATOM   441   C  CG  . GLU A 1 69  ? -12.828 31.931  27.477  1.00 41.48  ? 69  GLU A CG  1 
ATOM   442   C  CD  . GLU A 1 69  ? -13.238 32.392  26.068  1.00 61.39  ? 69  GLU A CD  1 
ATOM   443   O  OE1 . GLU A 1 69  ? -12.697 33.485  25.748  1.00 76.80  ? 69  GLU A OE1 1 
ATOM   444   O  OE2 . GLU A 1 69  ? -14.022 31.703  25.288  1.00 52.45  ? 69  GLU A OE2 1 
ATOM   445   N  N   . ALA A 1 70  ? -12.931 27.733  29.075  1.00 30.78  ? 70  ALA A N   1 
ATOM   446   C  CA  . ALA A 1 70  ? -13.284 26.326  29.256  1.00 27.50  ? 70  ALA A CA  1 
ATOM   447   C  C   . ALA A 1 70  ? -13.418 25.961  30.729  1.00 24.73  ? 70  ALA A C   1 
ATOM   448   O  O   . ALA A 1 70  ? -14.297 25.197  31.108  1.00 22.89  ? 70  ALA A O   1 
ATOM   449   C  CB  . ALA A 1 70  ? -12.255 25.431  28.571  1.00 25.37  ? 70  ALA A CB  1 
ATOM   450   N  N   . TRP A 1 71  ? -12.537 26.493  31.567  1.00 24.24  ? 71  TRP A N   1 
ATOM   451   C  CA  . TRP A 1 71  ? -12.622 26.159  32.976  1.00 25.18  ? 71  TRP A CA  1 
ATOM   452   C  C   . TRP A 1 71  ? -14.029 26.477  33.527  1.00 28.33  ? 71  TRP A C   1 
ATOM   453   O  O   . TRP A 1 71  ? -14.621 25.689  34.251  1.00 25.55  ? 71  TRP A O   1 
ATOM   454   C  CB  . TRP A 1 71  ? -11.520 26.925  33.701  1.00 22.50  ? 71  TRP A CB  1 
ATOM   455   C  CG  . TRP A 1 71  ? -11.552 26.583  35.155  1.00 23.98  ? 71  TRP A CG  1 
ATOM   456   C  CD1 . TRP A 1 71  ? -12.411 27.043  36.096  1.00 23.99  ? 71  TRP A CD1 1 
ATOM   457   C  CD2 . TRP A 1 71  ? -10.714 25.631  35.800  1.00 26.33  ? 71  TRP A CD2 1 
ATOM   458   N  NE1 . TRP A 1 71  ? -12.161 26.448  37.287  1.00 28.67  ? 71  TRP A NE1 1 
ATOM   459   C  CE2 . TRP A 1 71  ? -11.139 25.549  37.143  1.00 27.55  ? 71  TRP A CE2 1 
ATOM   460   C  CE3 . TRP A 1 71  ? -9.651  24.836  35.381  1.00 27.98  ? 71  TRP A CE3 1 
ATOM   461   C  CZ2 . TRP A 1 71  ? -10.523 24.705  38.076  1.00 29.27  ? 71  TRP A CZ2 1 
ATOM   462   C  CZ3 . TRP A 1 71  ? -9.070  23.961  36.286  1.00 28.88  ? 71  TRP A CZ3 1 
ATOM   463   C  CH2 . TRP A 1 71  ? -9.506  23.896  37.610  1.00 28.95  ? 71  TRP A CH2 1 
ATOM   464   N  N   . ASP A 1 72  ? -14.563 27.658  33.134  1.00 30.27  ? 72  ASP A N   1 
ATOM   465   C  CA  . ASP A 1 72  ? -15.854 28.175  33.540  1.00 27.87  ? 72  ASP A CA  1 
ATOM   466   C  C   . ASP A 1 72  ? -16.984 27.339  32.917  1.00 31.79  ? 72  ASP A C   1 
ATOM   467   O  O   . ASP A 1 72  ? -18.011 27.166  33.516  1.00 33.07  ? 72  ASP A O   1 
ATOM   468   C  CB  . ASP A 1 72  ? -15.951 29.643  33.223  1.00 24.95  ? 72  ASP A CB  1 
ATOM   469   C  CG  . ASP A 1 72  ? -15.006 30.562  33.980  1.00 24.49  ? 72  ASP A CG  1 
ATOM   470   O  OD1 . ASP A 1 72  ? -14.409 30.146  34.978  1.00 25.75  ? 72  ASP A OD1 1 
ATOM   471   O  OD2 . ASP A 1 72  ? -14.763 31.659  33.465  1.00 24.29  ? 72  ASP A OD2 1 
ATOM   472   N  N   . ARG A 1 73  ? -16.832 26.744  31.747  1.00 28.77  ? 73  ARG A N   1 
ATOM   473   C  CA  . ARG A 1 73  ? -17.868 25.845  31.242  1.00 26.16  ? 73  ARG A CA  1 
ATOM   474   C  C   . ARG A 1 73  ? -17.826 24.485  31.918  1.00 26.76  ? 73  ARG A C   1 
ATOM   475   O  O   . ARG A 1 73  ? -18.774 23.769  31.865  1.00 34.02  ? 73  ARG A O   1 
ATOM   476   C  CB  . ARG A 1 73  ? -17.756 25.685  29.719  1.00 26.55  ? 73  ARG A CB  1 
ATOM   477   C  CG  . ARG A 1 73  ? -17.740 27.011  28.953  1.00 28.16  ? 73  ARG A CG  1 
ATOM   478   C  CD  . ARG A 1 73  ? -17.200 26.812  27.533  1.00 25.78  ? 73  ARG A CD  1 
ATOM   479   N  NE  . ARG A 1 73  ? -17.843 25.683  26.831  1.00 26.13  ? 73  ARG A NE  1 
ATOM   480   C  CZ  . ARG A 1 73  ? -17.522 25.255  25.620  1.00 23.93  ? 73  ARG A CZ  1 
ATOM   481   N  NH1 . ARG A 1 73  ? -16.398 25.722  25.091  1.00 26.44  ? 73  ARG A NH1 1 
ATOM   482   N  NH2 . ARG A 1 73  ? -18.278 24.375  24.972  1.00 23.88  ? 73  ARG A NH2 1 
ATOM   483   N  N   . LEU A 1 74  ? -16.724 24.032  32.461  1.00 27.99  ? 74  LEU A N   1 
ATOM   484   C  CA  . LEU A 1 74  ? -16.641 22.651  32.877  1.00 26.11  ? 74  LEU A CA  1 
ATOM   485   C  C   . LEU A 1 74  ? -16.911 22.487  34.369  1.00 25.17  ? 74  LEU A C   1 
ATOM   486   O  O   . LEU A 1 74  ? -17.183 21.406  34.816  1.00 23.88  ? 74  LEU A O   1 
ATOM   487   C  CB  . LEU A 1 74  ? -15.211 22.193  32.603  1.00 29.53  ? 74  LEU A CB  1 
ATOM   488   C  CG  . LEU A 1 74  ? -14.857 21.942  31.135  1.00 31.84  ? 74  LEU A CG  1 
ATOM   489   C  CD1 . LEU A 1 74  ? -13.374 21.672  30.959  1.00 32.34  ? 74  LEU A CD1 1 
ATOM   490   C  CD2 . LEU A 1 74  ? -15.646 20.757  30.651  1.00 33.10  ? 74  LEU A CD2 1 
ATOM   491   N  N   . PHE A 1 75  ? -16.566 23.487  35.157  1.00 24.26  ? 75  PHE A N   1 
ATOM   492   C  CA  . PHE A 1 75  ? -16.448 23.360  36.601  1.00 30.34  ? 75  PHE A CA  1 
ATOM   493   C  C   . PHE A 1 75  ? -17.147 24.545  37.244  1.00 35.39  ? 75  PHE A C   1 
ATOM   494   O  O   . PHE A 1 75  ? -17.340 25.576  36.589  1.00 36.99  ? 75  PHE A O   1 
ATOM   495   C  CB  . PHE A 1 75  ? -14.994 23.551  37.033  1.00 30.52  ? 75  PHE A CB  1 
ATOM   496   C  CG  . PHE A 1 75  ? -14.066 22.524  36.425  1.00 31.27  ? 75  PHE A CG  1 
ATOM   497   C  CD1 . PHE A 1 75  ? -14.355 21.187  36.512  1.00 34.89  ? 75  PHE A CD1 1 
ATOM   498   C  CD2 . PHE A 1 75  ? -12.977 22.919  35.676  1.00 34.67  ? 75  PHE A CD2 1 
ATOM   499   C  CE1 . PHE A 1 75  ? -13.532 20.256  35.924  1.00 40.71  ? 75  PHE A CE1 1 
ATOM   500   C  CE2 . PHE A 1 75  ? -12.176 21.985  35.072  1.00 35.13  ? 75  PHE A CE2 1 
ATOM   501   C  CZ  . PHE A 1 75  ? -12.459 20.661  35.204  1.00 39.02  ? 75  PHE A CZ  1 
ATOM   502   N  N   . SER A 1 76  ? -17.518 24.462  38.526  1.00 40.70  ? 76  SER A N   1 
ATOM   503   C  CA  . SER A 1 76  ? -18.051 25.694  39.111  1.00 41.43  ? 76  SER A CA  1 
ATOM   504   C  C   . SER A 1 76  ? -17.470 25.892  40.487  1.00 30.99  ? 76  SER A C   1 
ATOM   505   O  O   . SER A 1 76  ? -16.843 25.000  41.025  1.00 25.04  ? 76  SER A O   1 
ATOM   506   C  CB  . SER A 1 76  ? -19.551 25.719  39.132  1.00 50.76  ? 76  SER A CB  1 
ATOM   507   O  OG  . SER A 1 76  ? -19.927 24.577  39.871  1.00 40.86  ? 76  SER A OG  1 
ATOM   508   N  N   . GLY A 1 77  ? -17.613 27.082  41.037  1.00 28.71  ? 77  GLY A N   1 
ATOM   509   C  CA  . GLY A 1 77  ? -16.928 27.294  42.303  1.00 26.51  ? 77  GLY A CA  1 
ATOM   510   C  C   . GLY A 1 77  ? -15.631 28.042  42.037  1.00 26.45  ? 77  GLY A C   1 
ATOM   511   O  O   . GLY A 1 77  ? -15.581 28.878  41.152  1.00 26.59  ? 77  GLY A O   1 
ATOM   512   N  N   . ALA A 1 78  ? -14.611 27.763  42.833  1.00 26.38  ? 78  ALA A N   1 
ATOM   513   C  CA  . ALA A 1 78  ? -13.394 28.553  42.873  1.00 29.30  ? 78  ALA A CA  1 
ATOM   514   C  C   . ALA A 1 78  ? -12.528 28.218  41.658  1.00 28.95  ? 78  ALA A C   1 
ATOM   515   O  O   . ALA A 1 78  ? -12.565 27.072  41.156  1.00 32.59  ? 78  ALA A O   1 
ATOM   516   C  CB  . ALA A 1 78  ? -12.669 28.265  44.193  1.00 28.07  ? 78  ALA A CB  1 
ATOM   517   N  N   . ARG A 1 79  ? -11.833 29.248  41.159  1.00 24.11  ? 79  ARG A N   1 
ATOM   518   C  CA  . ARG A 1 79  ? -11.000 29.122  39.962  1.00 27.45  ? 79  ARG A CA  1 
ATOM   519   C  C   . ARG A 1 79  ? -9.551  29.319  40.380  1.00 30.88  ? 79  ARG A C   1 
ATOM   520   O  O   . ARG A 1 79  ? -9.281  29.998  41.373  1.00 27.28  ? 79  ARG A O   1 
ATOM   521   C  CB  . ARG A 1 79  ? -11.139 30.246  38.931  1.00 25.29  ? 79  ARG A CB  1 
ATOM   522   C  CG  . ARG A 1 79  ? -12.533 30.265  38.395  1.00 27.73  ? 79  ARG A CG  1 
ATOM   523   C  CD  . ARG A 1 79  ? -12.750 31.598  37.714  1.00 27.63  ? 79  ARG A CD  1 
ATOM   524   N  NE  . ARG A 1 79  ? -12.510 31.372  36.300  1.00 27.92  ? 79  ARG A NE  1 
ATOM   525   C  CZ  . ARG A 1 79  ? -11.450 31.814  35.703  1.00 27.62  ? 79  ARG A CZ  1 
ATOM   526   N  NH1 . ARG A 1 79  ? -10.464 32.395  36.366  1.00 26.65  ? 79  ARG A NH1 1 
ATOM   527   N  NH2 . ARG A 1 79  ? -11.368 31.618  34.415  1.00 28.08  ? 79  ARG A NH2 1 
ATOM   528   N  N   . PRO A 1 80  ? -8.568  28.765  39.640  1.00 26.33  ? 80  PRO A N   1 
ATOM   529   C  CA  . PRO A 1 80  ? -7.173  29.153  39.859  1.00 28.77  ? 80  PRO A CA  1 
ATOM   530   C  C   . PRO A 1 80  ? -6.999  30.674  39.809  1.00 23.86  ? 80  PRO A C   1 
ATOM   531   O  O   . PRO A 1 80  ? -7.486  31.329  38.914  1.00 25.52  ? 80  PRO A O   1 
ATOM   532   C  CB  . PRO A 1 80  ? -6.418  28.456  38.691  1.00 27.71  ? 80  PRO A CB  1 
ATOM   533   C  CG  . PRO A 1 80  ? -7.330  27.286  38.350  1.00 26.60  ? 80  PRO A CG  1 
ATOM   534   C  CD  . PRO A 1 80  ? -8.747  27.835  38.525  1.00 26.02  ? 80  PRO A CD  1 
ATOM   535   N  N   . ALA A 1 81  ? -6.245  31.200  40.755  1.00 22.20  ? 81  ALA A N   1 
ATOM   536   C  CA  . ALA A 1 81  ? -6.085  32.632  40.933  1.00 23.04  ? 81  ALA A CA  1 
ATOM   537   C  C   . ALA A 1 81  ? -5.570  33.346  39.690  1.00 23.26  ? 81  ALA A C   1 
ATOM   538   O  O   . ALA A 1 81  ? -5.917  34.490  39.450  1.00 27.23  ? 81  ALA A O   1 
ATOM   539   C  CB  . ALA A 1 81  ? -5.180  32.860  42.135  1.00 21.42  ? 81  ALA A CB  1 
ATOM   540   N  N   . GLY A 1 82  ? -4.697  32.717  38.906  1.00 28.64  ? 82  GLY A N   1 
ATOM   541   C  CA  . GLY A 1 82  ? -4.032  33.431  37.820  1.00 27.88  ? 82  GLY A CA  1 
ATOM   542   C  C   . GLY A 1 82  ? -4.580  33.092  36.422  1.00 23.09  ? 82  GLY A C   1 
ATOM   543   O  O   . GLY A 1 82  ? -4.005  33.505  35.395  1.00 24.53  ? 82  GLY A O   1 
ATOM   544   N  N   . LEU A 1 83  ? -5.691  32.352  36.386  1.00 20.98  ? 83  LEU A N   1 
ATOM   545   C  CA  . LEU A 1 83  ? -6.184  31.812  35.127  1.00 20.88  ? 83  LEU A CA  1 
ATOM   546   C  C   . LEU A 1 83  ? -6.945  32.880  34.364  1.00 21.32  ? 83  LEU A C   1 
ATOM   547   O  O   . LEU A 1 83  ? -7.979  33.235  34.783  1.00 28.09  ? 83  LEU A O   1 
ATOM   548   C  CB  . LEU A 1 83  ? -7.023  30.556  35.356  1.00 20.41  ? 83  LEU A CB  1 
ATOM   549   C  CG  . LEU A 1 83  ? -7.575  29.859  34.110  1.00 23.36  ? 83  LEU A CG  1 
ATOM   550   C  CD1 . LEU A 1 83  ? -6.509  29.473  33.095  1.00 24.80  ? 83  LEU A CD1 1 
ATOM   551   C  CD2 . LEU A 1 83  ? -8.242  28.609  34.467  1.00 24.27  ? 83  LEU A CD2 1 
ATOM   552   N  N   . HIS A 1 84  ? -6.508  33.300  33.197  1.00 21.90  ? 84  HIS A N   1 
ATOM   553   C  CA  . HIS A 1 84  ? -7.154  34.252  32.312  1.00 22.33  ? 84  HIS A CA  1 
ATOM   554   C  C   . HIS A 1 84  ? -6.771  33.873  30.873  1.00 23.82  ? 84  HIS A C   1 
ATOM   555   O  O   . HIS A 1 84  ? -5.885  33.033  30.631  1.00 24.91  ? 84  HIS A O   1 
ATOM   556   C  CB  . HIS A 1 84  ? -6.692  35.682  32.640  1.00 19.26  ? 84  HIS A CB  1 
ATOM   557   C  CG  . HIS A 1 84  ? -5.228  35.869  32.781  1.00 22.70  ? 84  HIS A CG  1 
ATOM   558   N  ND1 . HIS A 1 84  ? -4.601  35.922  34.027  1.00 28.74  ? 84  HIS A ND1 1 
ATOM   559   C  CD2 . HIS A 1 84  ? -4.218  35.947  31.862  1.00 21.96  ? 84  HIS A CD2 1 
ATOM   560   C  CE1 . HIS A 1 84  ? -3.285  36.059  33.887  1.00 24.34  ? 84  HIS A CE1 1 
ATOM   561   N  NE2 . HIS A 1 84  ? -3.018  36.035  32.569  1.00 23.48  ? 84  HIS A NE2 1 
ATOM   562   N  N   . PRO A 1 85  ? -7.428  34.458  29.861  1.00 26.53  ? 85  PRO A N   1 
ATOM   563   C  CA  . PRO A 1 85  ? -7.056  34.234  28.465  1.00 25.42  ? 85  PRO A CA  1 
ATOM   564   C  C   . PRO A 1 85  ? -5.707  34.863  28.222  1.00 25.31  ? 85  PRO A C   1 
ATOM   565   O  O   . PRO A 1 85  ? -5.311  35.790  28.933  1.00 26.00  ? 85  PRO A O   1 
ATOM   566   C  CB  . PRO A 1 85  ? -8.146  34.975  27.719  1.00 27.32  ? 85  PRO A CB  1 
ATOM   567   C  CG  . PRO A 1 85  ? -9.277  34.923  28.699  1.00 26.89  ? 85  PRO A CG  1 
ATOM   568   C  CD  . PRO A 1 85  ? -8.608  35.319  29.975  1.00 28.41  ? 85  PRO A CD  1 
ATOM   569   N  N   . PHE A 1 86  ? -4.952  34.276  27.299  1.00 25.14  ? 86  PHE A N   1 
ATOM   570   C  CA  . PHE A 1 86  ? -3.667  34.849  26.916  1.00 26.17  ? 86  PHE A CA  1 
ATOM   571   C  C   . PHE A 1 86  ? -3.873  36.310  26.550  1.00 22.76  ? 86  PHE A C   1 
ATOM   572   O  O   . PHE A 1 86  ? -4.801  36.636  25.832  1.00 21.86  ? 86  PHE A O   1 
ATOM   573   C  CB  . PHE A 1 86  ? -3.115  33.994  25.766  1.00 27.25  ? 86  PHE A CB  1 
ATOM   574   C  CG  . PHE A 1 86  ? -1.782  34.426  25.205  1.00 25.75  ? 86  PHE A CG  1 
ATOM   575   C  CD1 . PHE A 1 86  ? -1.709  35.456  24.271  1.00 27.44  ? 86  PHE A CD1 1 
ATOM   576   C  CD2 . PHE A 1 86  ? -0.625  33.820  25.606  1.00 27.97  ? 86  PHE A CD2 1 
ATOM   577   C  CE1 . PHE A 1 86  ? -0.488  35.888  23.788  1.00 27.60  ? 86  PHE A CE1 1 
ATOM   578   C  CE2 . PHE A 1 86  ? 0.610   34.245  25.104  1.00 29.49  ? 86  PHE A CE2 1 
ATOM   579   C  CZ  . PHE A 1 86  ? 0.671   35.253  24.184  1.00 27.69  ? 86  PHE A CZ  1 
ATOM   580   N  N   . ARG A 1 87  ? -2.976  37.163  27.034  1.00 24.57  ? 87  ARG A N   1 
ATOM   581   C  CA  . ARG A 1 87  ? -3.051  38.590  26.752  1.00 27.85  ? 87  ARG A CA  1 
ATOM   582   C  C   . ARG A 1 87  ? -2.224  38.943  25.507  1.00 29.16  ? 87  ARG A C   1 
ATOM   583   O  O   . ARG A 1 87  ? -1.006  38.744  25.533  1.00 27.56  ? 87  ARG A O   1 
ATOM   584   C  CB  . ARG A 1 87  ? -2.401  39.455  27.835  1.00 33.99  ? 87  ARG A CB  1 
ATOM   585   C  CG  . ARG A 1 87  ? -2.778  39.160  29.273  1.00 52.78  ? 87  ARG A CG  1 
ATOM   586   C  CD  . ARG A 1 87  ? -2.542  40.322  30.248  1.00 65.92  ? 87  ARG A CD  1 
ATOM   587   N  NE  . ARG A 1 87  ? -3.691  40.103  31.145  1.00 90.74  ? 87  ARG A NE  1 
ATOM   588   C  CZ  . ARG A 1 87  ? -3.733  39.664  32.419  1.00 86.13  ? 87  ARG A CZ  1 
ATOM   589   N  NH1 . ARG A 1 87  ? -2.609  39.648  33.116  1.00 71.71  ? 87  ARG A NH1 1 
ATOM   590   N  NH2 . ARG A 1 87  ? -4.893  39.300  33.004  1.00 71.95  ? 87  ARG A NH2 1 
ATOM   591   N  N   . GLU A 1 88  ? -2.906  39.428  24.434  1.00 31.39  ? 88  GLU A N   1 
ATOM   592   C  CA  . GLU A 1 88  ? -2.304  39.870  23.197  1.00 26.77  ? 88  GLU A CA  1 
ATOM   593   C  C   . GLU A 1 88  ? -1.313  40.968  23.502  1.00 28.52  ? 88  GLU A C   1 
ATOM   594   O  O   . GLU A 1 88  ? -1.550  41.707  24.409  1.00 32.29  ? 88  GLU A O   1 
ATOM   595   C  CB  . GLU A 1 88  ? -3.281  40.515  22.246  1.00 31.91  ? 88  GLU A CB  1 
ATOM   596   C  CG  . GLU A 1 88  ? -4.067  39.488  21.440  1.00 42.83  ? 88  GLU A CG  1 
ATOM   597   C  CD  . GLU A 1 88  ? -4.495  40.000  20.079  1.00 54.76  ? 88  GLU A CD  1 
ATOM   598   O  OE1 . GLU A 1 88  ? -4.332  39.229  19.095  1.00 59.28  ? 88  GLU A OE1 1 
ATOM   599   O  OE2 . GLU A 1 88  ? -4.921  41.184  20.006  1.00 65.77  ? 88  GLU A OE2 1 
ATOM   600   N  N   . LEU A 1 89  ? -0.174  41.024  22.812  1.00 28.00  ? 89  LEU A N   1 
ATOM   601   C  CA  . LEU A 1 89  ? 0.785   42.093  22.999  1.00 30.02  ? 89  LEU A CA  1 
ATOM   602   C  C   . LEU A 1 89  ? 0.995   42.792  21.660  1.00 32.28  ? 89  LEU A C   1 
ATOM   603   O  O   . LEU A 1 89  ? 1.341   42.130  20.688  1.00 32.51  ? 89  LEU A O   1 
ATOM   604   C  CB  . LEU A 1 89  ? 2.106   41.587  23.554  1.00 31.60  ? 89  LEU A CB  1 
ATOM   605   C  CG  . LEU A 1 89  ? 2.047   40.910  24.913  1.00 31.33  ? 89  LEU A CG  1 
ATOM   606   C  CD1 . LEU A 1 89  ? 3.459   40.437  25.342  1.00 32.58  ? 89  LEU A CD1 1 
ATOM   607   C  CD2 . LEU A 1 89  ? 1.470   41.865  25.961  1.00 35.64  ? 89  LEU A CD2 1 
ATOM   608   N  N   . ASP A 1 90  ? 0.658   44.090  21.610  1.00 34.61  ? 90  ASP A N   1 
ATOM   609   C  CA  . ASP A 1 90  ? 0.701   44.890  20.397  1.00 36.77  ? 90  ASP A CA  1 
ATOM   610   C  C   . ASP A 1 90  ? 1.901   45.803  20.507  1.00 35.75  ? 90  ASP A C   1 
ATOM   611   O  O   . ASP A 1 90  ? 1.798   46.917  20.999  1.00 37.29  ? 90  ASP A O   1 
ATOM   612   C  CB  . ASP A 1 90  ? -0.581  45.661  20.146  1.00 41.71  ? 90  ASP A CB  1 
ATOM   613   C  CG  . ASP A 1 90  ? -1.652  44.878  19.393  1.00 58.31  ? 90  ASP A CG  1 
ATOM   614   O  OD1 . ASP A 1 90  ? -1.390  44.465  18.246  1.00 68.31  ? 90  ASP A OD1 1 
ATOM   615   O  OD2 . ASP A 1 90  ? -2.749  44.667  19.947  1.00 83.44  ? 90  ASP A OD2 1 
ATOM   616   N  N   . GLY A 1 91  ? 3.080   45.311  20.135  1.00 35.02  ? 91  GLY A N   1 
ATOM   617   C  CA  . GLY A 1 91  ? 4.271   46.136  20.233  1.00 31.73  ? 91  GLY A CA  1 
ATOM   618   C  C   . GLY A 1 91  ? 4.365   47.029  19.004  1.00 34.35  ? 91  GLY A C   1 
ATOM   619   O  O   . GLY A 1 91  ? 3.678   46.798  18.005  1.00 37.75  ? 91  GLY A O   1 
ATOM   620   N  N   . PRO A 1 92  ? 5.264   48.027  19.016  1.00 35.36  ? 92  PRO A N   1 
ATOM   621   C  CA  . PRO A 1 92  ? 5.486   48.884  17.852  1.00 36.06  ? 92  PRO A CA  1 
ATOM   622   C  C   . PRO A 1 92  ? 5.781   48.067  16.592  1.00 41.99  ? 92  PRO A C   1 
ATOM   623   O  O   . PRO A 1 92  ? 5.275   48.402  15.551  1.00 41.12  ? 92  PRO A O   1 
ATOM   624   C  CB  . PRO A 1 92  ? 6.674   49.737  18.196  1.00 39.94  ? 92  PRO A CB  1 
ATOM   625   C  CG  . PRO A 1 92  ? 7.119   49.359  19.601  1.00 40.97  ? 92  PRO A CG  1 
ATOM   626   C  CD  . PRO A 1 92  ? 6.177   48.288  20.122  1.00 42.41  ? 92  PRO A CD  1 
ATOM   627   N  N   . VAL A 1 93  ? 6.575   46.978  16.687  1.00 37.25  ? 93  VAL A N   1 
ATOM   628   C  CA  . VAL A 1 93  ? 7.002   46.202  15.530  1.00 28.17  ? 93  VAL A CA  1 
ATOM   629   C  C   . VAL A 1 93  ? 6.412   44.792  15.558  1.00 27.03  ? 93  VAL A C   1 
ATOM   630   O  O   . VAL A 1 93  ? 6.008   44.293  14.527  1.00 28.65  ? 93  VAL A O   1 
ATOM   631   C  CB  . VAL A 1 93  ? 8.540   46.098  15.536  1.00 30.29  ? 93  VAL A CB  1 
ATOM   632   C  CG1 . VAL A 1 93  ? 9.022   45.177  14.444  1.00 33.64  ? 93  VAL A CG1 1 
ATOM   633   C  CG2 . VAL A 1 93  ? 9.246   47.418  15.414  1.00 28.19  ? 93  VAL A CG2 1 
ATOM   634   N  N   . HIS A 1 94  ? 6.454   44.110  16.716  1.00 28.45  ? 94  HIS A N   1 
ATOM   635   C  CA  . HIS A 1 94  ? 6.082   42.701  16.814  1.00 30.23  ? 94  HIS A CA  1 
ATOM   636   C  C   . HIS A 1 94  ? 4.828   42.533  17.673  1.00 32.25  ? 94  HIS A C   1 
ATOM   637   O  O   . HIS A 1 94  ? 4.667   43.216  18.676  1.00 33.92  ? 94  HIS A O   1 
ATOM   638   C  CB  . HIS A 1 94  ? 7.261   41.880  17.368  1.00 29.32  ? 94  HIS A CB  1 
ATOM   639   C  CG  . HIS A 1 94  ? 8.507   41.920  16.558  1.00 28.81  ? 94  HIS A CG  1 
ATOM   640   N  ND1 . HIS A 1 94  ? 8.553   41.459  15.256  1.00 28.47  ? 94  HIS A ND1 1 
ATOM   641   C  CD2 . HIS A 1 94  ? 9.710   42.428  16.815  1.00 29.86  ? 94  HIS A CD2 1 
ATOM   642   C  CE1 . HIS A 1 94  ? 9.752   41.679  14.755  1.00 27.46  ? 94  HIS A CE1 1 
ATOM   643   N  NE2 . HIS A 1 94  ? 10.467  42.266  15.679  1.00 29.65  ? 94  HIS A NE2 1 
ATOM   644   N  N   . ARG A 1 95  ? 3.996   41.536  17.340  1.00 35.39  ? 95  ARG A N   1 
ATOM   645   C  CA  . ARG A 1 95  ? 2.730   41.316  18.031  1.00 35.90  ? 95  ARG A CA  1 
ATOM   646   C  C   . ARG A 1 95  ? 2.636   39.865  18.475  1.00 28.87  ? 95  ARG A C   1 
ATOM   647   O  O   . ARG A 1 95  ? 3.044   38.942  17.785  1.00 30.75  ? 95  ARG A O   1 
ATOM   648   C  CB  . ARG A 1 95  ? 1.628   41.856  17.121  1.00 46.14  ? 95  ARG A CB  1 
ATOM   649   C  CG  . ARG A 1 95  ? 2.038   43.237  16.536  1.00 92.06  ? 95  ARG A CG  1 
ATOM   650   C  CD  . ARG A 1 95  ? 1.363   43.900  15.231  1.00 95.19  ? 95  ARG A CD  1 
ATOM   651   N  NE  . ARG A 1 95  ? -0.043  43.488  15.365  1.00 115.28 ? 95  ARG A NE  1 
ATOM   652   C  CZ  . ARG A 1 95  ? -0.457  42.247  15.042  1.00 99.66  ? 95  ARG A CZ  1 
ATOM   653   N  NH1 . ARG A 1 95  ? -0.208  41.822  13.815  1.00 107.15 ? 95  ARG A NH1 1 
ATOM   654   N  NH2 . ARG A 1 95  ? -1.160  41.477  15.884  1.00 62.48  ? 95  ARG A NH2 1 
ATOM   655   N  N   . ALA A 1 96  ? 2.160   39.654  19.686  1.00 28.69  ? 96  ALA A N   1 
ATOM   656   C  CA  . ALA A 1 96  ? 1.898   38.316  20.169  1.00 28.38  ? 96  ALA A CA  1 
ATOM   657   C  C   . ALA A 1 96  ? 0.403   38.104  20.161  1.00 25.62  ? 96  ALA A C   1 
ATOM   658   O  O   . ALA A 1 96  ? -0.286  38.672  20.973  1.00 29.07  ? 96  ALA A O   1 
ATOM   659   C  CB  . ALA A 1 96  ? 2.516   38.118  21.557  1.00 32.45  ? 96  ALA A CB  1 
ATOM   660   N  N   . VAL A 1 97  ? -0.073  37.325  19.208  1.00 26.06  ? 97  VAL A N   1 
ATOM   661   C  CA  . VAL A 1 97  ? -1.500  37.107  18.994  1.00 27.58  ? 97  VAL A CA  1 
ATOM   662   C  C   . VAL A 1 97  ? -1.999  36.077  19.993  1.00 26.03  ? 97  VAL A C   1 
ATOM   663   O  O   . VAL A 1 97  ? -1.234  35.205  20.452  1.00 25.02  ? 97  VAL A O   1 
ATOM   664   C  CB  . VAL A 1 97  ? -1.756  36.547  17.575  1.00 29.37  ? 97  VAL A CB  1 
ATOM   665   C  CG1 . VAL A 1 97  ? -1.297  37.518  16.557  1.00 32.61  ? 97  VAL A CG1 1 
ATOM   666   C  CG2 . VAL A 1 97  ? -1.073  35.207  17.279  1.00 33.24  ? 97  VAL A CG2 1 
ATOM   667   N  N   . ALA A 1 98  ? -3.301  36.127  20.225  1.00 20.54  ? 98  ALA A N   1 
ATOM   668   C  CA  . ALA A 1 98  ? -3.965  35.118  21.021  1.00 21.02  ? 98  ALA A CA  1 
ATOM   669   C  C   . ALA A 1 98  ? -4.860  34.260  20.158  1.00 23.43  ? 98  ALA A C   1 
ATOM   670   O  O   . ALA A 1 98  ? -5.609  34.790  19.364  1.00 25.28  ? 98  ALA A O   1 
ATOM   671   C  CB  . ALA A 1 98  ? -4.758  35.787  22.087  1.00 22.48  ? 98  ALA A CB  1 
ATOM   672   N  N   . THR A 1 99  ? -4.841  32.947  20.314  1.00 20.25  ? 99  THR A N   1 
ATOM   673   C  CA  . THR A 1 99  ? -5.580  32.104  19.411  1.00 23.17  ? 99  THR A CA  1 
ATOM   674   C  C   . THR A 1 99  ? -6.374  31.157  20.281  1.00 24.96  ? 99  THR A C   1 
ATOM   675   O  O   . THR A 1 99  ? -6.103  30.968  21.432  1.00 24.60  ? 99  THR A O   1 
ATOM   676   C  CB  . THR A 1 99  ? -4.713  31.357  18.392  1.00 22.87  ? 99  THR A CB  1 
ATOM   677   O  OG1 . THR A 1 99  ? -3.812  30.528  19.123  1.00 23.15  ? 99  THR A OG1 1 
ATOM   678   C  CG2 . THR A 1 99  ? -4.036  32.349  17.461  1.00 21.56  ? 99  THR A CG2 1 
ATOM   679   N  N   . PRO A 1 100 ? -7.453  30.592  19.756  1.00 27.16  ? 100 PRO A N   1 
ATOM   680   C  CA  . PRO A 1 100 ? -8.291  29.705  20.525  1.00 29.98  ? 100 PRO A CA  1 
ATOM   681   C  C   . PRO A 1 100 ? -7.605  28.405  20.917  1.00 30.45  ? 100 PRO A C   1 
ATOM   682   O  O   . PRO A 1 100 ? -6.763  27.857  20.222  1.00 32.52  ? 100 PRO A O   1 
ATOM   683   C  CB  . PRO A 1 100 ? -9.455  29.416  19.534  1.00 29.12  ? 100 PRO A CB  1 
ATOM   684   C  CG  . PRO A 1 100 ? -9.408  30.514  18.526  1.00 29.64  ? 100 PRO A CG  1 
ATOM   685   C  CD  . PRO A 1 100 ? -7.928  30.752  18.364  1.00 31.29  ? 100 PRO A CD  1 
ATOM   686   N  N   . GLY A 1 101 ? -8.100  27.924  22.033  1.00 28.32  ? 101 GLY A N   1 
ATOM   687   C  CA  . GLY A 1 101 ? -7.575  26.794  22.731  1.00 29.27  ? 101 GLY A CA  1 
ATOM   688   C  C   . GLY A 1 101 ? -8.330  26.621  24.039  1.00 26.71  ? 101 GLY A C   1 
ATOM   689   O  O   . GLY A 1 101 ? -8.109  27.385  24.955  1.00 25.50  ? 101 GLY A O   1 
ATOM   690   N  N   . ASP A 1 102 ? -9.073  25.524  24.171  1.00 25.86  ? 102 ASP A N   1 
ATOM   691   C  CA  . ASP A 1 102 ? -9.695  25.209  25.436  1.00 23.14  ? 102 ASP A CA  1 
ATOM   692   C  C   . ASP A 1 102 ? -8.909  24.138  26.173  1.00 22.43  ? 102 ASP A C   1 
ATOM   693   O  O   . ASP A 1 102 ? -8.852  24.147  27.395  1.00 21.69  ? 102 ASP A O   1 
ATOM   694   C  CB  . ASP A 1 102 ? -11.143 24.774  25.240  1.00 22.11  ? 102 ASP A CB  1 
ATOM   695   C  CG  . ASP A 1 102 ? -12.031 25.871  24.672  1.00 25.03  ? 102 ASP A CG  1 
ATOM   696   O  OD1 . ASP A 1 102 ? -11.750 27.055  24.998  1.00 23.90  ? 102 ASP A OD1 1 
ATOM   697   O  OD2 . ASP A 1 102 ? -12.986 25.511  23.910  1.00 26.80  ? 102 ASP A OD2 1 
ATOM   698   N  N   . LEU A 1 103 ? -8.422  23.143  25.452  1.00 19.47  ? 103 LEU A N   1 
ATOM   699   C  CA  . LEU A 1 103 ? -7.683  22.065  26.077  1.00 22.47  ? 103 LEU A CA  1 
ATOM   700   C  C   . LEU A 1 103 ? -6.350  21.919  25.362  1.00 23.78  ? 103 LEU A C   1 
ATOM   701   O  O   . LEU A 1 103 ? -6.253  22.106  24.138  1.00 22.04  ? 103 LEU A O   1 
ATOM   702   C  CB  . LEU A 1 103 ? -8.441  20.754  25.957  1.00 23.51  ? 103 LEU A CB  1 
ATOM   703   C  CG  . LEU A 1 103 ? -9.770  20.680  26.701  1.00 26.18  ? 103 LEU A CG  1 
ATOM   704   C  CD1 . LEU A 1 103 ? -10.403 19.353  26.383  1.00 34.55  ? 103 LEU A CD1 1 
ATOM   705   C  CD2 . LEU A 1 103 ? -9.582  20.771  28.153  1.00 28.42  ? 103 LEU A CD2 1 
ATOM   706   N  N   . LEU A 1 104 ? -5.344  21.577  26.171  1.00 25.71  ? 104 LEU A N   1 
ATOM   707   C  CA  . LEU A 1 104 ? -3.982  21.303  25.736  1.00 22.22  ? 104 LEU A CA  1 
ATOM   708   C  C   . LEU A 1 104 ? -3.660  19.877  26.166  1.00 21.21  ? 104 LEU A C   1 
ATOM   709   O  O   . LEU A 1 104 ? -3.827  19.516  27.319  1.00 17.46  ? 104 LEU A O   1 
ATOM   710   C  CB  . LEU A 1 104 ? -3.050  22.298  26.420  1.00 23.54  ? 104 LEU A CB  1 
ATOM   711   C  CG  . LEU A 1 104 ? -1.552  21.972  26.312  1.00 24.94  ? 104 LEU A CG  1 
ATOM   712   C  CD1 . LEU A 1 104 ? -1.018  22.131  24.895  1.00 23.71  ? 104 LEU A CD1 1 
ATOM   713   C  CD2 . LEU A 1 104 ? -0.819  22.894  27.219  1.00 25.54  ? 104 LEU A CD2 1 
ATOM   714   N  N   . PHE A 1 105 ? -3.159  19.071  25.227  1.00 21.94  ? 105 PHE A N   1 
ATOM   715   C  CA  . PHE A 1 105 ? -2.471  17.841  25.544  1.00 20.84  ? 105 PHE A CA  1 
ATOM   716   C  C   . PHE A 1 105 ? -1.002  17.992  25.106  1.00 21.62  ? 105 PHE A C   1 
ATOM   717   O  O   . PHE A 1 105 ? -0.705  18.195  23.942  1.00 21.88  ? 105 PHE A O   1 
ATOM   718   C  CB  . PHE A 1 105 ? -3.203  16.687  24.878  1.00 20.18  ? 105 PHE A CB  1 
ATOM   719   C  CG  . PHE A 1 105 ? -4.651  16.531  25.294  1.00 23.51  ? 105 PHE A CG  1 
ATOM   720   C  CD1 . PHE A 1 105 ? -4.987  15.918  26.499  1.00 25.80  ? 105 PHE A CD1 1 
ATOM   721   C  CD2 . PHE A 1 105 ? -5.671  17.034  24.506  1.00 24.53  ? 105 PHE A CD2 1 
ATOM   722   C  CE1 . PHE A 1 105 ? -6.309  15.796  26.903  1.00 27.40  ? 105 PHE A CE1 1 
ATOM   723   C  CE2 . PHE A 1 105 ? -6.985  16.942  24.932  1.00 27.73  ? 105 PHE A CE2 1 
ATOM   724   C  CZ  . PHE A 1 105 ? -7.300  16.318  26.123  1.00 25.80  ? 105 PHE A CZ  1 
ATOM   725   N  N   . HIS A 1 106 ? -0.083  17.990  26.082  1.00 21.54  ? 106 HIS A N   1 
ATOM   726   C  CA  . HIS A 1 106 ? 1.344   18.065  25.850  1.00 20.34  ? 106 HIS A CA  1 
ATOM   727   C  C   . HIS A 1 106 ? 1.866   16.669  26.091  1.00 20.32  ? 106 HIS A C   1 
ATOM   728   O  O   . HIS A 1 106 ? 1.963   16.263  27.233  1.00 24.60  ? 106 HIS A O   1 
ATOM   729   C  CB  . HIS A 1 106 ? 1.992   19.011  26.855  1.00 21.81  ? 106 HIS A CB  1 
ATOM   730   C  CG  . HIS A 1 106 ? 3.478   19.206  26.667  1.00 21.34  ? 106 HIS A CG  1 
ATOM   731   N  ND1 . HIS A 1 106 ? 4.278   19.758  27.644  1.00 19.50  ? 106 HIS A ND1 1 
ATOM   732   C  CD2 . HIS A 1 106 ? 4.270   18.967  25.576  1.00 22.12  ? 106 HIS A CD2 1 
ATOM   733   C  CE1 . HIS A 1 106 ? 5.513   19.816  27.199  1.00 21.74  ? 106 HIS A CE1 1 
ATOM   734   N  NE2 . HIS A 1 106 ? 5.532   19.361  25.931  1.00 25.01  ? 106 HIS A NE2 1 
ATOM   735   N  N   . ILE A 1 107 ? 2.103   15.932  25.003  1.00 20.77  ? 107 ILE A N   1 
ATOM   736   C  CA  . ILE A 1 107 ? 2.408   14.511  25.038  1.00 19.38  ? 107 ILE A CA  1 
ATOM   737   C  C   . ILE A 1 107 ? 3.888   14.314  24.650  1.00 18.64  ? 107 ILE A C   1 
ATOM   738   O  O   . ILE A 1 107 ? 4.326   14.800  23.611  1.00 18.96  ? 107 ILE A O   1 
ATOM   739   C  CB  . ILE A 1 107 ? 1.503   13.729  24.086  1.00 20.02  ? 107 ILE A CB  1 
ATOM   740   C  CG1 . ILE A 1 107 ? 0.028   14.051  24.302  1.00 25.54  ? 107 ILE A CG1 1 
ATOM   741   C  CG2 . ILE A 1 107 ? 1.828   12.232  24.188  1.00 20.39  ? 107 ILE A CG2 1 
ATOM   742   C  CD1 . ILE A 1 107 ? -0.918  13.329  23.360  1.00 26.11  ? 107 ILE A CD1 1 
ATOM   743   N  N   . ARG A 1 108 ? 4.650   13.620  25.503  1.00 18.03  ? 108 ARG A N   1 
ATOM   744   C  CA  . ARG A 1 108 ? 6.078   13.560  25.323  1.00 18.26  ? 108 ARG A CA  1 
ATOM   745   C  C   . ARG A 1 108 ? 6.492   12.132  25.543  1.00 19.66  ? 108 ARG A C   1 
ATOM   746   O  O   . ARG A 1 108 ? 5.959   11.434  26.407  1.00 21.11  ? 108 ARG A O   1 
ATOM   747   C  CB  . ARG A 1 108 ? 6.843   14.427  26.318  1.00 20.02  ? 108 ARG A CB  1 
ATOM   748   C  CG  . ARG A 1 108 ? 6.779   15.906  26.016  1.00 22.01  ? 108 ARG A CG  1 
ATOM   749   C  CD  . ARG A 1 108 ? 7.456   16.714  27.127  1.00 24.77  ? 108 ARG A CD  1 
ATOM   750   N  NE  . ARG A 1 108 ? 6.759   16.726  28.419  1.00 24.25  ? 108 ARG A NE  1 
ATOM   751   C  CZ  . ARG A 1 108 ? 7.008   17.602  29.387  1.00 26.61  ? 108 ARG A CZ  1 
ATOM   752   N  NH1 . ARG A 1 108 ? 8.020   18.460  29.282  1.00 28.80  ? 108 ARG A NH1 1 
ATOM   753   N  NH2 . ARG A 1 108 ? 6.255   17.628  30.493  1.00 27.70  ? 108 ARG A NH2 1 
ATOM   754   N  N   . ALA A 1 109 ? 7.520   11.737  24.811  1.00 20.99  ? 109 ALA A N   1 
ATOM   755   C  CA  . ALA A 1 109 ? 8.132   10.445  25.033  1.00 22.96  ? 109 ALA A CA  1 
ATOM   756   C  C   . ALA A 1 109 ? 9.474   10.372  24.332  1.00 22.95  ? 109 ALA A C   1 
ATOM   757   O  O   . ALA A 1 109 ? 9.806   11.224  23.528  1.00 24.33  ? 109 ALA A O   1 
ATOM   758   C  CB  . ALA A 1 109 ? 7.203   9.407   24.442  1.00 25.92  ? 109 ALA A CB  1 
ATOM   759   N  N   . SER A 1 110 ? 10.120  9.226   24.468  1.00 25.79  ? 110 SER A N   1 
ATOM   760   C  CA  . SER A 1 110 ? 11.369  8.991   23.790  1.00 26.01  ? 110 SER A CA  1 
ATOM   761   C  C   . SER A 1 110 ? 11.163  8.580   22.341  1.00 30.24  ? 110 SER A C   1 
ATOM   762   O  O   . SER A 1 110 ? 12.166  8.500   21.650  1.00 31.97  ? 110 SER A O   1 
ATOM   763   C  CB  . SER A 1 110 ? 12.120  7.955   24.514  1.00 28.09  ? 110 SER A CB  1 
ATOM   764   O  OG  . SER A 1 110 ? 11.482  6.701   24.353  1.00 34.81  ? 110 SER A OG  1 
ATOM   765   N  N   . ARG A 1 111 ? 9.921   8.321   21.899  1.00 30.80  ? 111 ARG A N   1 
ATOM   766   C  CA  . ARG A 1 111 ? 9.614   7.909   20.536  1.00 37.64  ? 111 ARG A CA  1 
ATOM   767   C  C   . ARG A 1 111 ? 8.277   8.493   20.098  1.00 31.96  ? 111 ARG A C   1 
ATOM   768   O  O   . ARG A 1 111 ? 7.341   8.493   20.887  1.00 26.53  ? 111 ARG A O   1 
ATOM   769   C  CB  . ARG A 1 111 ? 9.345   6.396   20.539  1.00 41.71  ? 111 ARG A CB  1 
ATOM   770   C  CG  . ARG A 1 111 ? 10.525  5.439   20.647  1.00 45.81  ? 111 ARG A CG  1 
ATOM   771   C  CD  . ARG A 1 111 ? 10.150  4.110   21.309  1.00 54.24  ? 111 ARG A CD  1 
ATOM   772   N  NE  . ARG A 1 111 ? 8.961   3.329   20.904  1.00 59.36  ? 111 ARG A NE  1 
ATOM   773   C  CZ  . ARG A 1 111 ? 8.533   2.158   21.488  1.00 54.19  ? 111 ARG A CZ  1 
ATOM   774   N  NH1 . ARG A 1 111 ? 9.042   1.802   22.675  1.00 51.43  ? 111 ARG A NH1 1 
ATOM   775   N  NH2 . ARG A 1 111 ? 7.591   1.359   20.922  1.00 52.83  ? 111 ARG A NH2 1 
ATOM   776   N  N   . LEU A 1 112 ? 8.140   8.863   18.823  1.00 27.59  ? 112 LEU A N   1 
ATOM   777   C  CA  . LEU A 1 112 ? 6.908   9.462   18.363  1.00 25.85  ? 112 LEU A CA  1 
ATOM   778   C  C   . LEU A 1 112 ? 5.695   8.524   18.416  1.00 25.49  ? 112 LEU A C   1 
ATOM   779   O  O   . LEU A 1 112 ? 4.592   8.931   18.649  1.00 30.45  ? 112 LEU A O   1 
ATOM   780   C  CB  . LEU A 1 112 ? 7.173   9.952   16.968  1.00 23.91  ? 112 LEU A CB  1 
ATOM   781   C  CG  . LEU A 1 112 ? 6.045   10.807  16.390  1.00 28.79  ? 112 LEU A CG  1 
ATOM   782   C  CD1 . LEU A 1 112 ? 5.860   12.000  17.246  1.00 29.81  ? 112 LEU A CD1 1 
ATOM   783   C  CD2 . LEU A 1 112 ? 6.382   11.281  15.004  1.00 34.02  ? 112 LEU A CD2 1 
ATOM   784   N  N   . ASP A 1 113 ? 5.875   7.247   18.192  1.00 23.42  ? 113 ASP A N   1 
ATOM   785   C  CA  . ASP A 1 113 ? 4.808   6.306   18.083  1.00 23.30  ? 113 ASP A CA  1 
ATOM   786   C  C   . ASP A 1 113 ? 4.080   6.196   19.411  1.00 25.01  ? 113 ASP A C   1 
ATOM   787   O  O   . ASP A 1 113 ? 2.865   6.038   19.401  1.00 26.56  ? 113 ASP A O   1 
ATOM   788   C  CB  . ASP A 1 113 ? 5.336   4.922   17.712  1.00 32.22  ? 113 ASP A CB  1 
ATOM   789   C  CG  . ASP A 1 113 ? 6.221   4.146   18.698  1.00 29.80  ? 113 ASP A CG  1 
ATOM   790   O  OD1 . ASP A 1 113 ? 6.967   4.732   19.438  1.00 36.22  ? 113 ASP A OD1 1 
ATOM   791   O  OD2 . ASP A 1 113 ? 6.057   2.961   18.861  1.00 31.32  ? 113 ASP A OD2 1 
ATOM   792   N  N   . LEU A 1 114 ? 4.772   6.292   20.553  1.00 20.85  ? 114 LEU A N   1 
ATOM   793   C  CA  . LEU A 1 114 ? 4.058   6.319   21.819  1.00 23.82  ? 114 LEU A CA  1 
ATOM   794   C  C   . LEU A 1 114 ? 3.155   7.566   21.933  1.00 23.89  ? 114 LEU A C   1 
ATOM   795   O  O   . LEU A 1 114 ? 2.053   7.496   22.478  1.00 25.59  ? 114 LEU A O   1 
ATOM   796   C  CB  . LEU A 1 114 ? 5.011   6.279   23.000  1.00 23.94  ? 114 LEU A CB  1 
ATOM   797   C  CG  . LEU A 1 114 ? 5.871   5.022   23.088  1.00 27.49  ? 114 LEU A CG  1 
ATOM   798   C  CD1 . LEU A 1 114 ? 6.942   5.135   24.135  1.00 27.38  ? 114 LEU A CD1 1 
ATOM   799   C  CD2 . LEU A 1 114 ? 4.987   3.841   23.356  1.00 31.31  ? 114 LEU A CD2 1 
ATOM   800   N  N   . CYS A 1 115 ? 3.687   8.701   21.488  1.00 21.79  ? 115 CYS A N   1 
ATOM   801   C  CA  . CYS A 1 115 ? 2.942   9.937   21.469  1.00 22.00  ? 115 CYS A CA  1 
ATOM   802   C  C   . CYS A 1 115 ? 1.712   9.760   20.612  1.00 20.83  ? 115 CYS A C   1 
ATOM   803   O  O   . CYS A 1 115 ? 0.619   10.181  20.984  1.00 23.23  ? 115 CYS A O   1 
ATOM   804   C  CB  . CYS A 1 115 ? 3.791   11.114  20.990  1.00 23.58  ? 115 CYS A CB  1 
ATOM   805   S  SG  . CYS A 1 115 ? 5.222   11.413  22.086  1.00 25.52  ? 115 CYS A SG  1 
ATOM   806   N  N   . PHE A 1 116 ? 1.900   9.180   19.456  1.00 22.16  ? 116 PHE A N   1 
ATOM   807   C  CA  . PHE A 1 116 ? 0.830   9.110   18.475  1.00 23.88  ? 116 PHE A CA  1 
ATOM   808   C  C   . PHE A 1 116 ? -0.225  8.128   18.968  1.00 23.19  ? 116 PHE A C   1 
ATOM   809   O  O   . PHE A 1 116 ? -1.422  8.394   18.812  1.00 26.78  ? 116 PHE A O   1 
ATOM   810   C  CB  . PHE A 1 116 ? 1.411   8.676   17.134  1.00 22.87  ? 116 PHE A CB  1 
ATOM   811   C  CG  . PHE A 1 116 ? 0.420   8.829   16.002  1.00 25.46  ? 116 PHE A CG  1 
ATOM   812   C  CD1 . PHE A 1 116 ? 0.320   10.025  15.337  1.00 25.19  ? 116 PHE A CD1 1 
ATOM   813   C  CD2 . PHE A 1 116 ? -0.335  7.749   15.553  1.00 27.30  ? 116 PHE A CD2 1 
ATOM   814   C  CE1 . PHE A 1 116 ? -0.608  10.182  14.325  1.00 28.49  ? 116 PHE A CE1 1 
ATOM   815   C  CE2 . PHE A 1 116 ? -1.281  7.899   14.552  1.00 27.76  ? 116 PHE A CE2 1 
ATOM   816   C  CZ  . PHE A 1 116 ? -1.402  9.118   13.924  1.00 29.55  ? 116 PHE A CZ  1 
ATOM   817   N  N   . ALA A 1 117 ? 0.209   7.026   19.588  1.00 21.25  ? 117 ALA A N   1 
ATOM   818   C  CA  . ALA A 1 117 ? -0.767  6.066   20.108  1.00 22.45  ? 117 ALA A CA  1 
ATOM   819   C  C   . ALA A 1 117 ? -1.661  6.686   21.204  1.00 26.13  ? 117 ALA A C   1 
ATOM   820   O  O   . ALA A 1 117 ? -2.876  6.456   21.230  1.00 27.18  ? 117 ALA A O   1 
ATOM   821   C  CB  . ALA A 1 117 ? -0.128  4.802   20.626  1.00 22.46  ? 117 ALA A CB  1 
ATOM   822   N  N   . LEU A 1 118 ? -1.070  7.466   22.112  1.00 23.92  ? 118 LEU A N   1 
ATOM   823   C  CA  . LEU A 1 118 ? -1.815  8.098   23.194  1.00 24.77  ? 118 LEU A CA  1 
ATOM   824   C  C   . LEU A 1 118 ? -2.740  9.176   22.613  1.00 21.64  ? 118 LEU A C   1 
ATOM   825   O  O   . LEU A 1 118 ? -3.912  9.260   22.954  1.00 23.18  ? 118 LEU A O   1 
ATOM   826   C  CB  . LEU A 1 118 ? -0.867  8.649   24.278  1.00 22.89  ? 118 LEU A CB  1 
ATOM   827   C  CG  . LEU A 1 118 ? -1.563  9.271   25.486  1.00 25.32  ? 118 LEU A CG  1 
ATOM   828   C  CD1 . LEU A 1 118 ? -2.481  8.279   26.163  1.00 27.21  ? 118 LEU A CD1 1 
ATOM   829   C  CD2 . LEU A 1 118 ? -0.652  9.800   26.549  1.00 28.11  ? 118 LEU A CD2 1 
ATOM   830   N  N   . ALA A 1 119 ? -2.239  10.014  21.711  1.00 22.63  ? 119 ALA A N   1 
ATOM   831   C  CA  . ALA A 1 119 ? -3.098  11.033  21.073  1.00 23.64  ? 119 ALA A CA  1 
ATOM   832   C  C   . ALA A 1 119 ? -4.294  10.408  20.368  1.00 24.17  ? 119 ALA A C   1 
ATOM   833   O  O   . ALA A 1 119 ? -5.372  10.943  20.409  1.00 25.34  ? 119 ALA A O   1 
ATOM   834   C  CB  . ALA A 1 119 ? -2.292  11.842  20.067  1.00 22.52  ? 119 ALA A CB  1 
ATOM   835   N  N   . THR A 1 120 ? -4.079  9.284   19.698  1.00 22.46  ? 120 THR A N   1 
ATOM   836   C  CA  . THR A 1 120 ? -5.124  8.580   19.012  1.00 26.03  ? 120 THR A CA  1 
ATOM   837   C  C   . THR A 1 120 ? -6.203  8.186   20.018  1.00 28.43  ? 120 THR A C   1 
ATOM   838   O  O   . THR A 1 120 ? -7.373  8.339   19.726  1.00 30.38  ? 120 THR A O   1 
ATOM   839   C  CB  . THR A 1 120 ? -4.535  7.327   18.351  1.00 30.02  ? 120 THR A CB  1 
ATOM   840   O  OG1 . THR A 1 120 ? -3.778  7.808   17.251  1.00 28.98  ? 120 THR A OG1 1 
ATOM   841   C  CG2 . THR A 1 120 ? -5.570  6.441   17.698  1.00 29.71  ? 120 THR A CG2 1 
ATOM   842   N  N   . GLU A 1 121 ? -5.822  7.584   21.136  1.00 24.08  ? 121 GLU A N   1 
ATOM   843   C  CA  . GLU A 1 121 ? -6.800  7.162   22.122  1.00 27.54  ? 121 GLU A CA  1 
ATOM   844   C  C   . GLU A 1 121 ? -7.575  8.349   22.696  1.00 26.76  ? 121 GLU A C   1 
ATOM   845   O  O   . GLU A 1 121 ? -8.759  8.234   22.947  1.00 28.55  ? 121 GLU A O   1 
ATOM   846   C  CB  . GLU A 1 121 ? -6.179  6.413   23.304  1.00 32.08  ? 121 GLU A CB  1 
ATOM   847   C  CG  . GLU A 1 121 ? -5.744  5.002   22.948  1.00 37.51  ? 121 GLU A CG  1 
ATOM   848   C  CD  . GLU A 1 121 ? -6.964  4.090   22.857  1.00 42.97  ? 121 GLU A CD  1 
ATOM   849   O  OE1 . GLU A 1 121 ? -8.136  4.516   23.205  1.00 56.95  ? 121 GLU A OE1 1 
ATOM   850   O  OE2 . GLU A 1 121 ? -6.661  2.937   22.444  1.00 41.63  ? 121 GLU A OE2 1 
ATOM   851   N  N   . ILE A 1 122 ? -6.894  9.444   22.996  1.00 26.57  ? 122 ILE A N   1 
ATOM   852   C  CA  . ILE A 1 122 ? -7.543  10.597  23.593  1.00 27.39  ? 122 ILE A CA  1 
ATOM   853   C  C   . ILE A 1 122 ? -8.559  11.146  22.573  1.00 29.77  ? 122 ILE A C   1 
ATOM   854   O  O   . ILE A 1 122 ? -9.719  11.344  22.897  1.00 27.45  ? 122 ILE A O   1 
ATOM   855   C  CB  . ILE A 1 122 ? -6.468  11.632  23.997  1.00 25.98  ? 122 ILE A CB  1 
ATOM   856   C  CG1 . ILE A 1 122 ? -5.742  11.206  25.192  1.00 26.72  ? 122 ILE A CG1 1 
ATOM   857   C  CG2 . ILE A 1 122 ? -7.031  13.038  24.187  1.00 23.60  ? 122 ILE A CG2 1 
ATOM   858   C  CD1 . ILE A 1 122 ? -4.457  11.969  25.381  1.00 29.49  ? 122 ILE A CD1 1 
ATOM   859   N  N   . MET A 1 123 ? -8.162  11.384  21.315  1.00 29.31  ? 123 MET A N   1 
ATOM   860   C  CA  . MET A 1 123 ? -9.057  12.008  20.365  1.00 25.56  ? 123 MET A CA  1 
ATOM   861   C  C   . MET A 1 123 ? -10.183 11.041  19.977  1.00 28.44  ? 123 MET A C   1 
ATOM   862   O  O   . MET A 1 123 ? -11.254 11.459  19.574  1.00 37.64  ? 123 MET A O   1 
ATOM   863   C  CB  . MET A 1 123 ? -8.270  12.433  19.143  1.00 30.30  ? 123 MET A CB  1 
ATOM   864   C  CG  . MET A 1 123 ? -7.388  13.568  19.461  1.00 38.94  ? 123 MET A CG  1 
ATOM   865   S  SD  . MET A 1 123 ? -8.287  15.120  19.653  1.00 44.21  ? 123 MET A SD  1 
ATOM   866   C  CE  . MET A 1 123 ? -9.183  15.145  18.103  1.00 45.10  ? 123 MET A CE  1 
ATOM   867   N  N   . GLY A 1 124 ? -9.961  9.744   20.103  1.00 27.28  ? 124 GLY A N   1 
ATOM   868   C  CA  . GLY A 1 124 ? -10.993 8.763   19.861  1.00 26.22  ? 124 GLY A CA  1 
ATOM   869   C  C   . GLY A 1 124 ? -12.123 8.902   20.852  1.00 28.71  ? 124 GLY A C   1 
ATOM   870   O  O   . GLY A 1 124 ? -13.246 8.718   20.461  1.00 31.12  ? 124 GLY A O   1 
ATOM   871   N  N   . ARG A 1 125 ? -11.805 9.221   22.111  1.00 35.08  ? 125 ARG A N   1 
ATOM   872   C  CA  . ARG A 1 125 ? -12.780 9.409   23.176  1.00 30.54  ? 125 ARG A CA  1 
ATOM   873   C  C   . ARG A 1 125 ? -13.452 10.764  23.019  1.00 26.84  ? 125 ARG A C   1 
ATOM   874   O  O   . ARG A 1 125 ? -14.493 10.973  23.592  1.00 34.62  ? 125 ARG A O   1 
ATOM   875   C  CB  . ARG A 1 125 ? -12.162 9.167   24.556  1.00 32.56  ? 125 ARG A CB  1 
ATOM   876   C  CG  . ARG A 1 125 ? -11.445 7.824   24.789  1.00 45.54  ? 125 ARG A CG  1 
ATOM   877   C  CD  . ARG A 1 125 ? -11.882 6.694   25.830  1.00 57.34  ? 125 ARG A CD  1 
ATOM   878   N  NE  . ARG A 1 125 ? -12.992 7.291   26.615  1.00 71.57  ? 125 ARG A NE  1 
ATOM   879   C  CZ  . ARG A 1 125 ? -13.022 7.687   27.917  1.00 61.91  ? 125 ARG A CZ  1 
ATOM   880   N  NH1 . ARG A 1 125 ? -12.150 7.183   28.742  1.00 54.55  ? 125 ARG A NH1 1 
ATOM   881   N  NH2 . ARG A 1 125 ? -13.915 8.526   28.447  1.00 60.32  ? 125 ARG A NH2 1 
ATOM   882   N  N   . LEU A 1 126 ? -12.883 11.691  22.292  1.00 24.65  ? 126 LEU A N   1 
ATOM   883   C  CA  . LEU A 1 126 ? -13.388 13.057  22.271  1.00 26.78  ? 126 LEU A CA  1 
ATOM   884   C  C   . LEU A 1 126 ? -14.060 13.367  20.957  1.00 31.64  ? 126 LEU A C   1 
ATOM   885   O  O   . LEU A 1 126 ? -14.505 14.496  20.848  1.00 28.28  ? 126 LEU A O   1 
ATOM   886   C  CB  . LEU A 1 126 ? -12.274 14.096  22.445  1.00 28.00  ? 126 LEU A CB  1 
ATOM   887   C  CG  . LEU A 1 126 ? -11.640 14.196  23.843  1.00 29.73  ? 126 LEU A CG  1 
ATOM   888   C  CD1 . LEU A 1 126 ? -10.516 15.206  23.858  1.00 31.16  ? 126 LEU A CD1 1 
ATOM   889   C  CD2 . LEU A 1 126 ? -12.642 14.518  24.941  1.00 31.35  ? 126 LEU A CD2 1 
ATOM   890   N  N   . ARG A 1 127 ? -14.032 12.430  19.974  1.00 42.19  ? 127 ARG A N   1 
ATOM   891   C  CA  . ARG A 1 127 ? -14.537 12.615  18.615  1.00 47.45  ? 127 ARG A CA  1 
ATOM   892   C  C   . ARG A 1 127 ? -15.946 13.166  18.773  1.00 44.17  ? 127 ARG A C   1 
ATOM   893   O  O   . ARG A 1 127 ? -16.701 12.687  19.601  1.00 42.82  ? 127 ARG A O   1 
ATOM   894   C  CB  . ARG A 1 127 ? -14.526 11.239  17.905  1.00 65.19  ? 127 ARG A CB  1 
ATOM   895   C  CG  . ARG A 1 127 ? -14.833 10.932  16.426  1.00 80.97  ? 127 ARG A CG  1 
ATOM   896   C  CD  . ARG A 1 127 ? -13.998 9.822   15.675  1.00 78.65  ? 127 ARG A CD  1 
ATOM   897   N  NE  . ARG A 1 127 ? -12.688 10.461  15.401  1.00 112.41 ? 127 ARG A NE  1 
ATOM   898   C  CZ  . ARG A 1 127 ? -11.421 10.153  15.826  1.00 101.29 ? 127 ARG A CZ  1 
ATOM   899   N  NH1 . ARG A 1 127 ? -11.169 8.921   16.243  1.00 79.21  ? 127 ARG A NH1 1 
ATOM   900   N  NH2 . ARG A 1 127 ? -10.391 11.028  15.765  1.00 74.72  ? 127 ARG A NH2 1 
ATOM   901   N  N   . GLY A 1 128 ? -16.292 14.241  18.076  1.00 43.63  ? 128 GLY A N   1 
ATOM   902   C  CA  . GLY A 1 128 ? -17.654 14.718  18.173  1.00 34.11  ? 128 GLY A CA  1 
ATOM   903   C  C   . GLY A 1 128 ? -17.899 15.638  19.362  1.00 34.50  ? 128 GLY A C   1 
ATOM   904   O  O   . GLY A 1 128 ? -18.921 16.241  19.403  1.00 36.12  ? 128 GLY A O   1 
ATOM   905   N  N   . ALA A 1 129 ? -16.964 15.848  20.280  1.00 33.10  ? 129 ALA A N   1 
ATOM   906   C  CA  . ALA A 1 129 ? -17.120 16.852  21.336  1.00 28.09  ? 129 ALA A CA  1 
ATOM   907   C  C   . ALA A 1 129 ? -16.168 18.026  21.233  1.00 25.13  ? 129 ALA A C   1 
ATOM   908   O  O   . ALA A 1 129 ? -16.334 18.982  21.967  1.00 25.89  ? 129 ALA A O   1 
ATOM   909   C  CB  . ALA A 1 129 ? -16.852 16.194  22.670  1.00 31.69  ? 129 ALA A CB  1 
ATOM   910   N  N   . VAL A 1 130 ? -15.115 17.900  20.416  1.00 26.98  ? 130 VAL A N   1 
ATOM   911   C  CA  . VAL A 1 130 ? -14.074 18.903  20.309  1.00 30.03  ? 130 VAL A CA  1 
ATOM   912   C  C   . VAL A 1 130 ? -13.727 19.145  18.847  1.00 26.32  ? 130 VAL A C   1 
ATOM   913   O  O   . VAL A 1 130 ? -14.009 18.342  18.005  1.00 26.51  ? 130 VAL A O   1 
ATOM   914   C  CB  . VAL A 1 130 ? -12.818 18.505  21.112  1.00 31.24  ? 130 VAL A CB  1 
ATOM   915   C  CG1 . VAL A 1 130 ? -13.081 18.093  22.555  1.00 31.44  ? 130 VAL A CG1 1 
ATOM   916   C  CG2 . VAL A 1 130 ? -12.088 17.369  20.435  1.00 37.94  ? 130 VAL A CG2 1 
ATOM   917   N  N   . THR A 1 131 ? -13.065 20.247  18.567  1.00 24.48  ? 131 THR A N   1 
ATOM   918   C  CA  . THR A 1 131 ? -12.628 20.594  17.238  1.00 25.80  ? 131 THR A CA  1 
ATOM   919   C  C   . THR A 1 131 ? -11.121 20.862  17.331  1.00 26.49  ? 131 THR A C   1 
ATOM   920   O  O   . THR A 1 131 ? -10.684 21.668  18.144  1.00 24.25  ? 131 THR A O   1 
ATOM   921   C  CB  . THR A 1 131 ? -13.399 21.828  16.756  1.00 26.56  ? 131 THR A CB  1 
ATOM   922   O  OG1 . THR A 1 131 ? -14.679 21.226  16.620  1.00 27.85  ? 131 THR A OG1 1 
ATOM   923   C  CG2 . THR A 1 131 ? -12.884 22.379  15.444  1.00 25.64  ? 131 THR A CG2 1 
ATOM   924   N  N   . PRO A 1 132 ? -10.286 20.252  16.474  1.00 28.97  ? 132 PRO A N   1 
ATOM   925   C  CA  . PRO A 1 132 ? -8.848  20.466  16.563  1.00 30.64  ? 132 PRO A CA  1 
ATOM   926   C  C   . PRO A 1 132 ? -8.513  21.887  16.131  1.00 30.20  ? 132 PRO A C   1 
ATOM   927   O  O   . PRO A 1 132 ? -9.054  22.359  15.155  1.00 28.03  ? 132 PRO A O   1 
ATOM   928   C  CB  . PRO A 1 132 ? -8.298  19.432  15.610  1.00 34.71  ? 132 PRO A CB  1 
ATOM   929   C  CG  . PRO A 1 132 ? -9.460  18.465  15.398  1.00 34.69  ? 132 PRO A CG  1 
ATOM   930   C  CD  . PRO A 1 132 ? -10.668 19.332  15.402  1.00 31.96  ? 132 PRO A CD  1 
ATOM   931   N  N   . GLN A 1 133 ? -7.667  22.583  16.882  1.00 25.76  ? 133 GLN A N   1 
ATOM   932   C  CA  . GLN A 1 133 ? -7.167  23.863  16.453  1.00 23.55  ? 133 GLN A CA  1 
ATOM   933   C  C   . GLN A 1 133 ? -5.711  23.781  16.034  1.00 22.33  ? 133 GLN A C   1 
ATOM   934   O  O   . GLN A 1 133 ? -5.312  24.581  15.226  1.00 25.96  ? 133 GLN A O   1 
ATOM   935   C  CB  . GLN A 1 133 ? -7.081  24.865  17.601  1.00 31.13  ? 133 GLN A CB  1 
ATOM   936   C  CG  . GLN A 1 133 ? -8.429  25.239  18.184  1.00 39.91  ? 133 GLN A CG  1 
ATOM   937   C  CD  . GLN A 1 133 ? -9.301  25.936  17.163  1.00 44.90  ? 133 GLN A CD  1 
ATOM   938   O  OE1 . GLN A 1 133 ? -8.839  26.856  16.460  1.00 41.48  ? 133 GLN A OE1 1 
ATOM   939   N  NE2 . GLN A 1 133 ? -10.518 25.408  17.013  1.00 49.76  ? 133 GLN A NE2 1 
ATOM   940   N  N   . ASP A 1 134 ? -4.882  22.953  16.688  1.00 23.38  ? 134 ASP A N   1 
ATOM   941   C  CA  . ASP A 1 134 ? -3.463  22.884  16.379  1.00 23.62  ? 134 ASP A CA  1 
ATOM   942   C  C   . ASP A 1 134 ? -2.959  21.480  16.699  1.00 21.66  ? 134 ASP A C   1 
ATOM   943   O  O   . ASP A 1 134 ? -3.411  20.847  17.652  1.00 22.78  ? 134 ASP A O   1 
ATOM   944   C  CB  . ASP A 1 134 ? -2.700  23.990  17.082  1.00 25.76  ? 134 ASP A CB  1 
ATOM   945   C  CG  . ASP A 1 134 ? -1.366  24.324  16.430  1.00 30.59  ? 134 ASP A CG  1 
ATOM   946   O  OD1 . ASP A 1 134 ? -1.225  23.957  15.264  1.00 28.93  ? 134 ASP A OD1 1 
ATOM   947   O  OD2 . ASP A 1 134 ? -0.473  24.926  17.087  1.00 32.75  ? 134 ASP A OD2 1 
ATOM   948   N  N   . GLU A 1 135 ? -2.103  20.941  15.839  1.00 20.27  ? 135 GLU A N   1 
ATOM   949   C  CA  . GLU A 1 135 ? -1.468  19.653  16.070  1.00 19.33  ? 135 GLU A CA  1 
ATOM   950   C  C   . GLU A 1 135 ? -0.028  19.756  15.589  1.00 22.88  ? 135 GLU A C   1 
ATOM   951   O  O   . GLU A 1 135 ? 0.162   20.092  14.468  1.00 24.89  ? 135 GLU A O   1 
ATOM   952   C  CB  . GLU A 1 135 ? -2.150  18.545  15.297  1.00 20.11  ? 135 GLU A CB  1 
ATOM   953   C  CG  . GLU A 1 135 ? -1.511  17.193  15.592  1.00 22.86  ? 135 GLU A CG  1 
ATOM   954   C  CD  . GLU A 1 135 ? -2.198  16.002  14.917  1.00 26.55  ? 135 GLU A CD  1 
ATOM   955   O  OE1 . GLU A 1 135 ? -3.175  16.277  14.188  1.00 30.62  ? 135 GLU A OE1 1 
ATOM   956   O  OE2 . GLU A 1 135 ? -1.791  14.840  15.091  1.00 26.26  ? 135 GLU A OE2 1 
ATOM   957   N  N   . VAL A 1 136 ? 0.988   19.648  16.440  1.00 22.33  ? 136 VAL A N   1 
ATOM   958   C  CA  . VAL A 1 136 ? 2.377   19.755  16.041  1.00 19.91  ? 136 VAL A CA  1 
ATOM   959   C  C   . VAL A 1 136 ? 3.114   18.508  16.516  1.00 20.78  ? 136 VAL A C   1 
ATOM   960   O  O   . VAL A 1 136 ? 2.957   18.092  17.675  1.00 22.16  ? 136 VAL A O   1 
ATOM   961   C  CB  . VAL A 1 136 ? 2.999   21.036  16.594  1.00 24.19  ? 136 VAL A CB  1 
ATOM   962   C  CG1 . VAL A 1 136 ? 4.467   21.103  16.315  1.00 28.78  ? 136 VAL A CG1 1 
ATOM   963   C  CG2 . VAL A 1 136 ? 2.382   22.278  15.989  1.00 29.33  ? 136 VAL A CG2 1 
ATOM   964   N  N   . HIS A 1 137 ? 3.854   17.886  15.575  1.00 20.35  ? 137 HIS A N   1 
ATOM   965   C  CA  . HIS A 1 137 ? 4.708   16.756  15.859  1.00 20.61  ? 137 HIS A CA  1 
ATOM   966   C  C   . HIS A 1 137 ? 6.153   17.234  15.933  1.00 22.25  ? 137 HIS A C   1 
ATOM   967   O  O   . HIS A 1 137 ? 6.727   17.751  14.976  1.00 23.43  ? 137 HIS A O   1 
ATOM   968   C  CB  . HIS A 1 137 ? 4.518   15.690  14.805  1.00 21.88  ? 137 HIS A CB  1 
ATOM   969   C  CG  . HIS A 1 137 ? 3.148   15.107  14.701  1.00 23.96  ? 137 HIS A CG  1 
ATOM   970   N  ND1 . HIS A 1 137 ? 2.885   14.061  13.829  1.00 28.42  ? 137 HIS A ND1 1 
ATOM   971   C  CD2 . HIS A 1 137 ? 1.998   15.426  15.269  1.00 26.99  ? 137 HIS A CD2 1 
ATOM   972   C  CE1 . HIS A 1 137 ? 1.608   13.737  13.909  1.00 27.83  ? 137 HIS A CE1 1 
ATOM   973   N  NE2 . HIS A 1 137 ? 1.056   14.554  14.784  1.00 28.50  ? 137 HIS A NE2 1 
ATOM   974   N  N   . GLY A 1 138 ? 6.705   17.218  17.128  1.00 22.16  ? 138 GLY A N   1 
ATOM   975   C  CA  . GLY A 1 138 ? 7.990   17.827  17.369  1.00 19.54  ? 138 GLY A CA  1 
ATOM   976   C  C   . GLY A 1 138 ? 9.063   16.759  17.536  1.00 21.19  ? 138 GLY A C   1 
ATOM   977   O  O   . GLY A 1 138 ? 8.786   15.622  18.003  1.00 20.01  ? 138 GLY A O   1 
ATOM   978   N  N   . PHE A 1 139 ? 10.298  17.179  17.185  1.00 21.73  ? 139 PHE A N   1 
ATOM   979   C  CA  . PHE A 1 139 ? 11.458  16.304  17.278  1.00 23.43  ? 139 PHE A CA  1 
ATOM   980   C  C   . PHE A 1 139 ? 12.683  17.084  17.780  1.00 21.57  ? 139 PHE A C   1 
ATOM   981   O  O   . PHE A 1 139 ? 12.926  18.174  17.367  1.00 22.95  ? 139 PHE A O   1 
ATOM   982   C  CB  . PHE A 1 139 ? 11.580  15.637  15.903  1.00 23.45  ? 139 PHE A CB  1 
ATOM   983   C  CG  . PHE A 1 139 ? 11.725  16.595  14.748  1.00 23.72  ? 139 PHE A CG  1 
ATOM   984   C  CD1 . PHE A 1 139 ? 12.968  17.127  14.426  1.00 32.58  ? 139 PHE A CD1 1 
ATOM   985   C  CD2 . PHE A 1 139 ? 10.636  16.923  13.965  1.00 27.32  ? 139 PHE A CD2 1 
ATOM   986   C  CE1 . PHE A 1 139 ? 13.097  18.016  13.371  1.00 33.10  ? 139 PHE A CE1 1 
ATOM   987   C  CE2 . PHE A 1 139 ? 10.772  17.759  12.862  1.00 31.15  ? 139 PHE A CE2 1 
ATOM   988   C  CZ  . PHE A 1 139 ? 11.996  18.328  12.586  1.00 31.07  ? 139 PHE A CZ  1 
ATOM   989   N  N   . LYS A 1 140 ? 13.504  16.487  18.644  1.00 27.24  ? 140 LYS A N   1 
ATOM   990   C  CA  . LYS A 1 140 ? 14.825  16.979  19.015  1.00 33.41  ? 140 LYS A CA  1 
ATOM   991   C  C   . LYS A 1 140 ? 15.753  16.892  17.812  1.00 29.42  ? 140 LYS A C   1 
ATOM   992   O  O   . LYS A 1 140 ? 15.689  15.971  16.967  1.00 35.05  ? 140 LYS A O   1 
ATOM   993   C  CB  . LYS A 1 140 ? 15.465  16.164  20.155  1.00 51.57  ? 140 LYS A CB  1 
ATOM   994   C  CG  . LYS A 1 140 ? 16.962  15.538  20.122  1.00 66.87  ? 140 LYS A CG  1 
ATOM   995   C  CD  . LYS A 1 140 ? 17.408  14.591  21.287  1.00 56.93  ? 140 LYS A CD  1 
ATOM   996   C  CE  . LYS A 1 140 ? 18.841  14.662  21.872  1.00 49.79  ? 140 LYS A CE  1 
ATOM   997   N  N   . TYR A 1 141 ? 16.589  17.910  17.720  1.00 27.39  ? 141 TYR A N   1 
ATOM   998   C  CA  . TYR A 1 141 ? 17.326  18.129  16.494  1.00 31.17  ? 141 TYR A CA  1 
ATOM   999   C  C   . TYR A 1 141 ? 18.724  17.987  16.923  1.00 28.68  ? 141 TYR A C   1 
ATOM   1000  O  O   . TYR A 1 141 ? 19.135  18.936  17.473  1.00 34.82  ? 141 TYR A O   1 
ATOM   1001  C  CB  . TYR A 1 141 ? 17.000  19.530  15.982  1.00 33.29  ? 141 TYR A CB  1 
ATOM   1002  C  CG  . TYR A 1 141 ? 17.406  19.893  14.588  1.00 33.52  ? 141 TYR A CG  1 
ATOM   1003  C  CD1 . TYR A 1 141 ? 17.097  19.122  13.515  1.00 37.24  ? 141 TYR A CD1 1 
ATOM   1004  C  CD2 . TYR A 1 141 ? 18.034  21.089  14.375  1.00 50.25  ? 141 TYR A CD2 1 
ATOM   1005  C  CE1 . TYR A 1 141 ? 17.412  19.530  12.248  1.00 49.88  ? 141 TYR A CE1 1 
ATOM   1006  C  CE2 . TYR A 1 141 ? 18.466  21.477  13.133  1.00 54.26  ? 141 TYR A CE2 1 
ATOM   1007  C  CZ  . TYR A 1 141 ? 18.151  20.683  12.053  1.00 66.06  ? 141 TYR A CZ  1 
ATOM   1008  O  OH  . TYR A 1 141 ? 18.590  21.061  10.810  1.00 66.92  ? 141 TYR A OH  1 
ATOM   1009  N  N   . PHE A 1 142 ? 19.347  16.812  16.894  1.00 41.87  ? 142 PHE A N   1 
ATOM   1010  C  CA  . PHE A 1 142 ? 20.802  16.768  17.007  1.00 50.27  ? 142 PHE A CA  1 
ATOM   1011  C  C   . PHE A 1 142 ? 21.029  16.764  18.506  1.00 40.10  ? 142 PHE A C   1 
ATOM   1012  O  O   . PHE A 1 142 ? 20.450  15.910  19.151  1.00 47.52  ? 142 PHE A O   1 
ATOM   1013  C  CB  . PHE A 1 142 ? 21.731  17.817  16.299  1.00 49.05  ? 142 PHE A CB  1 
ATOM   1014  C  CG  . PHE A 1 142 ? 21.848  17.592  14.787  1.00 55.74  ? 142 PHE A CG  1 
ATOM   1015  C  CD1 . PHE A 1 142 ? 22.641  16.535  14.277  1.00 57.72  ? 142 PHE A CD1 1 
ATOM   1016  C  CD2 . PHE A 1 142 ? 21.108  18.386  13.885  1.00 50.36  ? 142 PHE A CD2 1 
ATOM   1017  C  CE1 . PHE A 1 142 ? 22.673  16.290  12.909  1.00 65.96  ? 142 PHE A CE1 1 
ATOM   1018  C  CE2 . PHE A 1 142 ? 21.151  18.147  12.520  1.00 48.14  ? 142 PHE A CE2 1 
ATOM   1019  C  CZ  . PHE A 1 142 ? 21.902  17.080  12.035  1.00 59.79  ? 142 PHE A CZ  1 
ATOM   1020  N  N   . ASP A 1 143 ? 21.792  17.771  18.976  1.00 29.76  ? 143 ASP A N   1 
ATOM   1021  C  CA  . ASP A 1 143 ? 22.334  17.832  20.306  1.00 29.01  ? 143 ASP A CA  1 
ATOM   1022  C  C   . ASP A 1 143 ? 21.640  18.965  21.036  1.00 26.47  ? 143 ASP A C   1 
ATOM   1023  O  O   . ASP A 1 143 ? 22.236  19.962  21.458  1.00 25.15  ? 143 ASP A O   1 
ATOM   1024  C  CB  . ASP A 1 143 ? 23.849  17.950  20.260  1.00 37.01  ? 143 ASP A CB  1 
ATOM   1025  C  CG  . ASP A 1 143 ? 24.422  19.153  19.509  1.00 50.02  ? 143 ASP A CG  1 
ATOM   1026  O  OD1 . ASP A 1 143 ? 23.941  19.424  18.353  1.00 44.83  ? 143 ASP A OD1 1 
ATOM   1027  O  OD2 . ASP A 1 143 ? 25.348  19.798  20.096  1.00 44.36  ? 143 ASP A OD2 1 
ATOM   1028  N  N   . GLU A 1 144 ? 20.354  18.752  21.210  1.00 29.49  ? 144 GLU A N   1 
ATOM   1029  C  CA  . GLU A 1 144 ? 19.426  19.694  21.834  1.00 29.89  ? 144 GLU A CA  1 
ATOM   1030  C  C   . GLU A 1 144 ? 19.411  21.060  21.156  1.00 25.38  ? 144 GLU A C   1 
ATOM   1031  O  O   . GLU A 1 144 ? 19.006  22.025  21.781  1.00 26.45  ? 144 GLU A O   1 
ATOM   1032  C  CB  . GLU A 1 144 ? 19.682  19.821  23.344  1.00 31.79  ? 144 GLU A CB  1 
ATOM   1033  C  CG  . GLU A 1 144 ? 19.548  18.502  24.088  1.00 31.21  ? 144 GLU A CG  1 
ATOM   1034  C  CD  . GLU A 1 144 ? 18.131  17.984  24.072  1.00 30.99  ? 144 GLU A CD  1 
ATOM   1035  O  OE1 . GLU A 1 144 ? 17.150  18.790  24.078  1.00 37.63  ? 144 GLU A OE1 1 
ATOM   1036  O  OE2 . GLU A 1 144 ? 18.085  16.721  24.010  1.00 37.10  ? 144 GLU A OE2 1 
ATOM   1037  N  N   . ARG A 1 145 ? 19.699  21.120  19.854  1.00 25.59  ? 145 ARG A N   1 
ATOM   1038  C  CA  . ARG A 1 145 ? 19.571  22.360  19.088  1.00 25.52  ? 145 ARG A CA  1 
ATOM   1039  C  C   . ARG A 1 145 ? 18.129  22.638  18.644  1.00 24.28  ? 145 ARG A C   1 
ATOM   1040  O  O   . ARG A 1 145 ? 17.284  21.772  18.565  1.00 25.31  ? 145 ARG A O   1 
ATOM   1041  C  CB  . ARG A 1 145 ? 20.633  22.364  17.988  1.00 24.44  ? 145 ARG A CB  1 
ATOM   1042  C  CG  . ARG A 1 145 ? 21.980  22.387  18.700  1.00 25.56  ? 145 ARG A CG  1 
ATOM   1043  C  CD  . ARG A 1 145 ? 23.086  22.586  17.776  1.00 27.95  ? 145 ARG A CD  1 
ATOM   1044  N  NE  . ARG A 1 145 ? 24.399  22.418  18.373  1.00 25.25  ? 145 ARG A NE  1 
ATOM   1045  C  CZ  . ARG A 1 145 ? 25.147  23.365  18.853  1.00 23.78  ? 145 ARG A CZ  1 
ATOM   1046  N  NH1 . ARG A 1 145 ? 24.802  24.640  18.771  1.00 24.30  ? 145 ARG A NH1 1 
ATOM   1047  N  NH2 . ARG A 1 145 ? 26.208  22.971  19.532  1.00 22.43  ? 145 ARG A NH2 1 
ATOM   1048  N  N   . ASP A 1 146 ? 17.854  23.910  18.437  1.00 24.84  ? 146 ASP A N   1 
ATOM   1049  C  CA  . ASP A 1 146 ? 16.644  24.352  17.791  1.00 23.54  ? 146 ASP A CA  1 
ATOM   1050  C  C   . ASP A 1 146 ? 16.974  24.628  16.341  1.00 22.91  ? 146 ASP A C   1 
ATOM   1051  O  O   . ASP A 1 146 ? 18.074  24.422  15.860  1.00 22.90  ? 146 ASP A O   1 
ATOM   1052  C  CB  . ASP A 1 146 ? 16.002  25.501  18.556  1.00 24.02  ? 146 ASP A CB  1 
ATOM   1053  C  CG  . ASP A 1 146 ? 16.851  26.747  18.705  1.00 24.26  ? 146 ASP A CG  1 
ATOM   1054  O  OD1 . ASP A 1 146 ? 17.688  26.937  17.809  1.00 19.09  ? 146 ASP A OD1 1 
ATOM   1055  O  OD2 . ASP A 1 146 ? 16.730  27.413  19.782  1.00 26.66  ? 146 ASP A OD2 1 
ATOM   1056  N  N   . MET A 1 147 ? 15.956  25.103  15.660  1.00 26.17  ? 147 MET A N   1 
ATOM   1057  C  CA  . MET A 1 147 ? 15.956  25.396  14.242  1.00 27.41  ? 147 MET A CA  1 
ATOM   1058  C  C   . MET A 1 147 ? 16.868  26.572  13.934  1.00 23.41  ? 147 MET A C   1 
ATOM   1059  O  O   . MET A 1 147 ? 17.300  26.738  12.833  1.00 22.69  ? 147 MET A O   1 
ATOM   1060  C  CB  . MET A 1 147 ? 14.526  25.772  13.817  1.00 35.13  ? 147 MET A CB  1 
ATOM   1061  C  CG  . MET A 1 147 ? 14.168  25.260  12.496  1.00 42.54  ? 147 MET A CG  1 
ATOM   1062  S  SD  . MET A 1 147 ? 14.474  23.506  12.199  1.00 41.49  ? 147 MET A SD  1 
ATOM   1063  C  CE  . MET A 1 147 ? 12.800  22.897  12.220  1.00 35.98  ? 147 MET A CE  1 
ATOM   1064  N  N   . LEU A 1 148 ? 17.213  27.428  14.883  1.00 21.13  ? 148 LEU A N   1 
ATOM   1065  C  CA  . LEU A 1 148 ? 18.207  28.463  14.621  1.00 19.26  ? 148 LEU A CA  1 
ATOM   1066  C  C   . LEU A 1 148 ? 19.622  27.956  14.830  1.00 16.07  ? 148 LEU A C   1 
ATOM   1067  O  O   . LEU A 1 148 ? 20.566  28.688  14.674  1.00 18.72  ? 148 LEU A O   1 
ATOM   1068  C  CB  . LEU A 1 148 ? 17.902  29.592  15.590  1.00 21.39  ? 148 LEU A CB  1 
ATOM   1069  C  CG  . LEU A 1 148 ? 16.488  30.192  15.543  1.00 25.13  ? 148 LEU A CG  1 
ATOM   1070  C  CD1 . LEU A 1 148 ? 16.362  31.265  16.619  1.00 25.82  ? 148 LEU A CD1 1 
ATOM   1071  C  CD2 . LEU A 1 148 ? 16.217  30.766  14.153  1.00 25.02  ? 148 LEU A CD2 1 
ATOM   1072  N  N   . GLY A 1 149 ? 19.790  26.736  15.272  1.00 16.74  ? 149 GLY A N   1 
ATOM   1073  C  CA  . GLY A 1 149 ? 21.084  26.106  15.402  1.00 20.31  ? 149 GLY A CA  1 
ATOM   1074  C  C   . GLY A 1 149 ? 21.745  26.294  16.777  1.00 23.87  ? 149 GLY A C   1 
ATOM   1075  O  O   . GLY A 1 149 ? 22.919  25.955  16.934  1.00 23.53  ? 149 GLY A O   1 
ATOM   1076  N  N   . PHE A 1 150 ? 20.992  26.835  17.755  1.00 23.88  ? 150 PHE A N   1 
ATOM   1077  C  CA  . PHE A 1 150 ? 21.475  27.031  19.110  1.00 22.22  ? 150 PHE A CA  1 
ATOM   1078  C  C   . PHE A 1 150 ? 20.945  25.943  20.036  1.00 23.83  ? 150 PHE A C   1 
ATOM   1079  O  O   . PHE A 1 150 ? 19.845  25.448  19.826  1.00 22.34  ? 150 PHE A O   1 
ATOM   1080  C  CB  . PHE A 1 150 ? 21.111  28.426  19.584  1.00 20.97  ? 150 PHE A CB  1 
ATOM   1081  C  CG  . PHE A 1 150 ? 22.073  29.471  19.035  1.00 17.23  ? 150 PHE A CG  1 
ATOM   1082  C  CD1 . PHE A 1 150 ? 21.970  29.888  17.741  1.00 18.18  ? 150 PHE A CD1 1 
ATOM   1083  C  CD2 . PHE A 1 150 ? 22.972  30.114  19.837  1.00 17.11  ? 150 PHE A CD2 1 
ATOM   1084  C  CE1 . PHE A 1 150 ? 22.784  30.893  17.260  1.00 21.96  ? 150 PHE A CE1 1 
ATOM   1085  C  CE2 . PHE A 1 150 ? 23.792  31.110  19.351  1.00 19.81  ? 150 PHE A CE2 1 
ATOM   1086  C  CZ  . PHE A 1 150 ? 23.709  31.485  18.060  1.00 20.83  ? 150 PHE A CZ  1 
ATOM   1087  N  N   . VAL A 1 151 ? 21.754  25.558  21.036  1.00 23.29  ? 151 VAL A N   1 
ATOM   1088  C  CA  . VAL A 1 151 ? 21.311  24.628  22.079  1.00 21.68  ? 151 VAL A CA  1 
ATOM   1089  C  C   . VAL A 1 151 ? 20.194  25.320  22.862  1.00 23.14  ? 151 VAL A C   1 
ATOM   1090  O  O   . VAL A 1 151 ? 20.319  26.494  23.264  1.00 23.57  ? 151 VAL A O   1 
ATOM   1091  C  CB  . VAL A 1 151 ? 22.455  24.188  23.040  1.00 21.11  ? 151 VAL A CB  1 
ATOM   1092  C  CG1 . VAL A 1 151 ? 21.934  23.233  24.096  1.00 23.36  ? 151 VAL A CG1 1 
ATOM   1093  C  CG2 . VAL A 1 151 ? 23.678  23.639  22.312  1.00 19.93  ? 151 VAL A CG2 1 
ATOM   1094  N  N   . ASP A 1 152 ? 19.130  24.556  23.140  1.00 24.37  ? 152 ASP A N   1 
ATOM   1095  C  CA  . ASP A 1 152 ? 17.889  25.087  23.660  1.00 27.24  ? 152 ASP A CA  1 
ATOM   1096  C  C   . ASP A 1 152 ? 17.519  24.216  24.854  1.00 24.18  ? 152 ASP A C   1 
ATOM   1097  O  O   . ASP A 1 152 ? 17.261  23.014  24.691  1.00 24.63  ? 152 ASP A O   1 
ATOM   1098  C  CB  . ASP A 1 152 ? 16.851  25.117  22.525  1.00 36.88  ? 152 ASP A CB  1 
ATOM   1099  C  CG  . ASP A 1 152 ? 15.559  25.914  22.737  1.00 36.69  ? 152 ASP A CG  1 
ATOM   1100  O  OD1 . ASP A 1 152 ? 15.012  25.727  23.871  1.00 34.04  ? 152 ASP A OD1 1 
ATOM   1101  O  OD2 . ASP A 1 152 ? 15.073  26.650  21.744  1.00 32.60  ? 152 ASP A OD2 1 
ATOM   1102  N  N   . GLY A 1 153 ? 17.475  24.844  26.029  1.00 26.53  ? 153 GLY A N   1 
ATOM   1103  C  CA  . GLY A 1 153 ? 17.201  24.139  27.280  1.00 26.92  ? 153 GLY A CA  1 
ATOM   1104  C  C   . GLY A 1 153 ? 18.218  24.410  28.409  1.00 24.49  ? 153 GLY A C   1 
ATOM   1105  O  O   . GLY A 1 153 ? 17.901  24.120  29.525  1.00 25.60  ? 153 GLY A O   1 
ATOM   1106  N  N   . THR A 1 154 ? 19.385  25.006  28.149  1.00 22.51  ? 154 THR A N   1 
ATOM   1107  C  CA  . THR A 1 154 ? 20.570  24.902  28.978  1.00 20.31  ? 154 THR A CA  1 
ATOM   1108  C  C   . THR A 1 154 ? 20.335  25.501  30.354  1.00 21.50  ? 154 THR A C   1 
ATOM   1109  O  O   . THR A 1 154 ? 20.700  24.931  31.365  1.00 18.82  ? 154 THR A O   1 
ATOM   1110  C  CB  . THR A 1 154 ? 21.682  25.667  28.291  1.00 22.81  ? 154 THR A CB  1 
ATOM   1111  O  OG1 . THR A 1 154 ? 21.792  25.174  26.954  1.00 23.01  ? 154 THR A OG1 1 
ATOM   1112  C  CG2 . THR A 1 154 ? 22.998  25.542  29.048  1.00 26.87  ? 154 THR A CG2 1 
ATOM   1113  N  N   . GLU A 1 155 ? 19.697  26.664  30.386  1.00 22.94  ? 155 GLU A N   1 
ATOM   1114  C  CA  . GLU A 1 155 ? 19.422  27.348  31.645  1.00 24.63  ? 155 GLU A CA  1 
ATOM   1115  C  C   . GLU A 1 155 ? 18.084  27.015  32.284  1.00 21.80  ? 155 GLU A C   1 
ATOM   1116  O  O   . GLU A 1 155 ? 17.705  27.650  33.242  1.00 20.92  ? 155 GLU A O   1 
ATOM   1117  C  CB  . GLU A 1 155 ? 19.630  28.850  31.472  1.00 26.65  ? 155 GLU A CB  1 
ATOM   1118  C  CG  . GLU A 1 155 ? 21.127  29.207  31.356  1.00 28.67  ? 155 GLU A CG  1 
ATOM   1119  C  CD  . GLU A 1 155 ? 21.980  28.841  32.561  1.00 29.69  ? 155 GLU A CD  1 
ATOM   1120  O  OE1 . GLU A 1 155 ? 21.573  29.312  33.599  1.00 39.83  ? 155 GLU A OE1 1 
ATOM   1121  O  OE2 . GLU A 1 155 ? 22.944  28.102  32.522  1.00 34.63  ? 155 GLU A OE2 1 
ATOM   1122  N  N   . ASN A 1 156 ? 17.430  25.934  31.874  1.00 20.67  ? 156 ASN A N   1 
ATOM   1123  C  CA  . ASN A 1 156 ? 16.233  25.522  32.575  1.00 20.72  ? 156 ASN A CA  1 
ATOM   1124  C  C   . ASN A 1 156 ? 16.545  25.176  34.013  1.00 24.46  ? 156 ASN A C   1 
ATOM   1125  O  O   . ASN A 1 156 ? 17.564  24.573  34.271  1.00 26.98  ? 156 ASN A O   1 
ATOM   1126  C  CB  . ASN A 1 156 ? 15.587  24.295  31.986  1.00 21.64  ? 156 ASN A CB  1 
ATOM   1127  C  CG  . ASN A 1 156 ? 14.513  24.647  30.993  1.00 22.95  ? 156 ASN A CG  1 
ATOM   1128  O  OD1 . ASN A 1 156 ? 13.817  25.678  31.146  1.00 26.12  ? 156 ASN A OD1 1 
ATOM   1129  N  ND2 . ASN A 1 156 ? 14.417  23.840  29.948  1.00 22.46  ? 156 ASN A ND2 1 
ATOM   1130  N  N   . PRO A 1 157 ? 15.673  25.476  34.983  1.00 25.68  ? 157 PRO A N   1 
ATOM   1131  C  CA  . PRO A 1 157 ? 15.930  25.045  36.352  1.00 25.80  ? 157 PRO A CA  1 
ATOM   1132  C  C   . PRO A 1 157 ? 15.824  23.538  36.455  1.00 25.18  ? 157 PRO A C   1 
ATOM   1133  O  O   . PRO A 1 157 ? 15.174  22.897  35.631  1.00 28.98  ? 157 PRO A O   1 
ATOM   1134  C  CB  . PRO A 1 157 ? 14.837  25.793  37.119  1.00 27.94  ? 157 PRO A CB  1 
ATOM   1135  C  CG  . PRO A 1 157 ? 13.695  25.837  36.133  1.00 29.92  ? 157 PRO A CG  1 
ATOM   1136  C  CD  . PRO A 1 157 ? 14.417  26.212  34.834  1.00 28.94  ? 157 PRO A CD  1 
ATOM   1137  N  N   . THR A 1 158 ? 16.499  22.987  37.463  1.00 28.05  ? 158 THR A N   1 
ATOM   1138  C  CA  . THR A 1 158 ? 16.414  21.556  37.734  1.00 31.63  ? 158 THR A CA  1 
ATOM   1139  C  C   . THR A 1 158 ? 16.132  21.295  39.224  1.00 33.01  ? 158 THR A C   1 
ATOM   1140  O  O   . THR A 1 158 ? 16.331  22.144  40.105  1.00 28.14  ? 158 THR A O   1 
ATOM   1141  C  CB  . THR A 1 158 ? 17.672  20.810  37.265  1.00 28.44  ? 158 THR A CB  1 
ATOM   1142  O  OG1 . THR A 1 158 ? 18.661  21.340  38.122  1.00 25.35  ? 158 THR A OG1 1 
ATOM   1143  C  CG2 . THR A 1 158 ? 17.983  21.005  35.786  1.00 33.04  ? 158 THR A CG2 1 
ATOM   1144  N  N   . GLY A 1 159 ? 15.640  20.078  39.457  1.00 37.40  ? 159 GLY A N   1 
ATOM   1145  C  CA  . GLY A 1 159 ? 15.361  19.559  40.779  1.00 41.35  ? 159 GLY A CA  1 
ATOM   1146  C  C   . GLY A 1 159 ? 14.460  20.493  41.561  1.00 40.50  ? 159 GLY A C   1 
ATOM   1147  O  O   . GLY A 1 159 ? 13.396  20.789  41.099  1.00 38.79  ? 159 GLY A O   1 
ATOM   1148  N  N   . ALA A 1 160 ? 14.899  20.934  42.747  1.00 43.57  ? 160 ALA A N   1 
ATOM   1149  C  CA  . ALA A 1 160 ? 14.037  21.597  43.705  1.00 42.25  ? 160 ALA A CA  1 
ATOM   1150  C  C   . ALA A 1 160 ? 13.804  22.993  43.187  1.00 36.18  ? 160 ALA A C   1 
ATOM   1151  O  O   . ALA A 1 160 ? 12.748  23.549  43.457  1.00 33.88  ? 160 ALA A O   1 
ATOM   1152  C  CB  . ALA A 1 160 ? 14.618  21.659  45.117  1.00 43.07  ? 160 ALA A CB  1 
ATOM   1153  N  N   . ALA A 1 161 ? 14.778  23.543  42.446  1.00 29.03  ? 161 ALA A N   1 
ATOM   1154  C  CA  . ALA A 1 161 ? 14.570  24.889  41.921  1.00 34.90  ? 161 ALA A CA  1 
ATOM   1155  C  C   . ALA A 1 161 ? 13.427  24.861  40.889  1.00 32.57  ? 161 ALA A C   1 
ATOM   1156  O  O   . ALA A 1 161 ? 12.612  25.773  40.820  1.00 31.94  ? 161 ALA A O   1 
ATOM   1157  C  CB  . ALA A 1 161 ? 15.835  25.447  41.346  1.00 30.25  ? 161 ALA A CB  1 
ATOM   1158  N  N   . ALA A 1 162 ? 13.356  23.772  40.127  1.00 29.50  ? 162 ALA A N   1 
ATOM   1159  C  CA  . ALA A 1 162 ? 12.300  23.584  39.155  1.00 31.34  ? 162 ALA A CA  1 
ATOM   1160  C  C   . ALA A 1 162 ? 10.936  23.403  39.840  1.00 32.80  ? 162 ALA A C   1 
ATOM   1161  O  O   . ALA A 1 162 ? 10.032  24.120  39.431  1.00 29.44  ? 162 ALA A O   1 
ATOM   1162  C  CB  . ALA A 1 162 ? 12.685  22.460  38.182  1.00 28.52  ? 162 ALA A CB  1 
ATOM   1163  N  N   . ARG A 1 163 ? 10.816  22.526  40.871  1.00 30.09  ? 163 ARG A N   1 
ATOM   1164  C  CA  . ARG A 1 163 ? 9.566   22.326  41.604  1.00 31.26  ? 163 ARG A CA  1 
ATOM   1165  C  C   . ARG A 1 163 ? 9.137   23.691  42.130  1.00 30.15  ? 163 ARG A C   1 
ATOM   1166  O  O   . ARG A 1 163 ? 7.984   24.062  41.941  1.00 29.91  ? 163 ARG A O   1 
ATOM   1167  C  CB  . ARG A 1 163 ? 9.524   21.336  42.784  1.00 44.81  ? 163 ARG A CB  1 
ATOM   1168  C  CG  . ARG A 1 163 ? 10.676  20.342  42.994  1.00 73.71  ? 163 ARG A CG  1 
ATOM   1169  C  CD  . ARG A 1 163 ? 10.625  19.404  44.229  1.00 78.52  ? 163 ARG A CD  1 
ATOM   1170  N  NE  . ARG A 1 163 ? 9.287   18.793  44.167  1.00 98.76  ? 163 ARG A NE  1 
ATOM   1171  C  CZ  . ARG A 1 163 ? 8.776   18.027  43.152  1.00 96.31  ? 163 ARG A CZ  1 
ATOM   1172  N  NH1 . ARG A 1 163 ? 9.541   17.617  42.125  1.00 77.50  ? 163 ARG A NH1 1 
ATOM   1173  N  NH2 . ARG A 1 163 ? 7.492   17.640  43.190  1.00 76.30  ? 163 ARG A NH2 1 
ATOM   1174  N  N   . ARG A 1 164 ? 10.050  24.497  42.694  1.00 29.36  ? 164 ARG A N   1 
ATOM   1175  C  CA  . ARG A 1 164 ? 9.651   25.753  43.305  1.00 33.51  ? 164 ARG A CA  1 
ATOM   1176  C  C   . ARG A 1 164 ? 9.255   26.746  42.228  1.00 29.19  ? 164 ARG A C   1 
ATOM   1177  O  O   . ARG A 1 164 ? 8.437   27.593  42.457  1.00 29.84  ? 164 ARG A O   1 
ATOM   1178  C  CB  . ARG A 1 164 ? 10.670  26.275  44.331  1.00 46.24  ? 164 ARG A CB  1 
ATOM   1179  C  CG  . ARG A 1 164 ? 9.958   26.921  45.530  1.00 72.82  ? 164 ARG A CG  1 
ATOM   1180  C  CD  . ARG A 1 164 ? 10.835  27.598  46.589  1.00 92.16  ? 164 ARG A CD  1 
ATOM   1181  N  NE  . ARG A 1 164 ? 12.187  27.734  46.019  1.00 120.30 ? 164 ARG A NE  1 
ATOM   1182  C  CZ  . ARG A 1 164 ? 13.103  26.748  45.762  1.00 104.52 ? 164 ARG A CZ  1 
ATOM   1183  N  NH1 . ARG A 1 164 ? 13.012  25.521  46.281  1.00 87.57  ? 164 ARG A NH1 1 
ATOM   1184  N  NH2 . ARG A 1 164 ? 14.151  27.018  44.992  1.00 85.94  ? 164 ARG A NH2 1 
ATOM   1185  N  N   . ALA A 1 165 ? 9.772   26.660  41.007  1.00 29.95  ? 165 ALA A N   1 
ATOM   1186  C  CA  . ALA A 1 165 ? 9.453   27.662  39.984  1.00 26.90  ? 165 ALA A CA  1 
ATOM   1187  C  C   . ALA A 1 165 ? 8.118   27.351  39.277  1.00 28.13  ? 165 ALA A C   1 
ATOM   1188  O  O   . ALA A 1 165 ? 7.495   28.265  38.705  1.00 22.77  ? 165 ALA A O   1 
ATOM   1189  C  CB  . ALA A 1 165 ? 10.567  27.727  38.969  1.00 25.61  ? 165 ALA A CB  1 
ATOM   1190  N  N   . VAL A 1 166 ? 7.697   26.075  39.263  1.00 23.17  ? 166 VAL A N   1 
ATOM   1191  C  CA  . VAL A 1 166 ? 6.627   25.684  38.363  1.00 25.01  ? 166 VAL A CA  1 
ATOM   1192  C  C   . VAL A 1 166 ? 5.332   25.276  39.090  1.00 25.35  ? 166 VAL A C   1 
ATOM   1193  O  O   . VAL A 1 166 ? 4.268   25.431  38.498  1.00 22.43  ? 166 VAL A O   1 
ATOM   1194  C  CB  . VAL A 1 166 ? 7.023   24.657  37.273  1.00 28.13  ? 166 VAL A CB  1 
ATOM   1195  C  CG1 . VAL A 1 166 ? 8.419   24.856  36.717  1.00 27.94  ? 166 VAL A CG1 1 
ATOM   1196  C  CG2 . VAL A 1 166 ? 6.813   23.248  37.693  1.00 31.82  ? 166 VAL A CG2 1 
ATOM   1197  N  N   . LEU A 1 167 ? 5.405   24.785  40.350  1.00 23.63  ? 167 LEU A N   1 
ATOM   1198  C  CA  . LEU A 1 167 ? 4.229   24.254  41.034  1.00 25.22  ? 167 LEU A CA  1 
ATOM   1199  C  C   . LEU A 1 167 ? 3.550   25.276  41.961  1.00 26.75  ? 167 LEU A C   1 
ATOM   1200  O  O   . LEU A 1 167 ? 4.192   25.985  42.736  1.00 25.31  ? 167 LEU A O   1 
ATOM   1201  C  CB  . LEU A 1 167 ? 4.618   23.020  41.806  1.00 25.02  ? 167 LEU A CB  1 
ATOM   1202  C  CG  . LEU A 1 167 ? 5.152   21.873  40.943  1.00 31.05  ? 167 LEU A CG  1 
ATOM   1203  C  CD1 . LEU A 1 167 ? 5.349   20.618  41.807  1.00 33.97  ? 167 LEU A CD1 1 
ATOM   1204  C  CD2 . LEU A 1 167 ? 4.243   21.528  39.747  1.00 33.16  ? 167 LEU A CD2 1 
ATOM   1205  N  N   . VAL A 1 168 ? 2.227   25.408  41.798  1.00 25.66  ? 168 VAL A N   1 
ATOM   1206  C  CA  . VAL A 1 168 ? 1.453   26.285  42.638  1.00 27.42  ? 168 VAL A CA  1 
ATOM   1207  C  C   . VAL A 1 168 ? 1.570   25.725  44.063  1.00 28.90  ? 168 VAL A C   1 
ATOM   1208  O  O   . VAL A 1 168 ? 1.482   24.518  44.268  1.00 23.20  ? 168 VAL A O   1 
ATOM   1209  C  CB  . VAL A 1 168 ? -0.009  26.280  42.177  1.00 27.40  ? 168 VAL A CB  1 
ATOM   1210  C  CG1 . VAL A 1 168 ? -0.911  26.930  43.200  1.00 27.95  ? 168 VAL A CG1 1 
ATOM   1211  C  CG2 . VAL A 1 168 ? -0.162  26.937  40.815  1.00 29.59  ? 168 VAL A CG2 1 
ATOM   1212  N  N   . GLY A 1 169 ? 1.762   26.611  45.042  1.00 27.18  ? 169 GLY A N   1 
ATOM   1213  C  CA  . GLY A 1 169 ? 1.829   26.200  46.425  1.00 29.93  ? 169 GLY A CA  1 
ATOM   1214  C  C   . GLY A 1 169 ? 0.802   26.927  47.294  1.00 34.66  ? 169 GLY A C   1 
ATOM   1215  O  O   . GLY A 1 169 ? -0.367  27.095  46.922  1.00 33.12  ? 169 GLY A O   1 
ATOM   1216  N  N   . ALA A 1 170 ? 1.276   27.273  48.495  1.00 37.27  ? 170 ALA A N   1 
ATOM   1217  C  CA  . ALA A 1 170 ? 0.574   27.980  49.556  1.00 35.36  ? 170 ALA A CA  1 
ATOM   1218  C  C   . ALA A 1 170 ? -0.170  29.237  49.111  1.00 32.54  ? 170 ALA A C   1 
ATOM   1219  O  O   . ALA A 1 170 ? -1.164  29.611  49.700  1.00 29.82  ? 170 ALA A O   1 
ATOM   1220  C  CB  . ALA A 1 170 ? 1.667   28.444  50.493  1.00 38.66  ? 170 ALA A CB  1 
ATOM   1221  N  N   . GLU A 1 171 ? 0.336   29.910  48.078  1.00 31.50  ? 171 GLU A N   1 
ATOM   1222  C  CA  . GLU A 1 171 ? -0.265  31.146  47.587  1.00 27.42  ? 171 GLU A CA  1 
ATOM   1223  C  C   . GLU A 1 171 ? -1.628  30.909  46.945  1.00 27.51  ? 171 GLU A C   1 
ATOM   1224  O  O   . GLU A 1 171 ? -2.321  31.891  46.691  1.00 25.42  ? 171 GLU A O   1 
ATOM   1225  C  CB  . GLU A 1 171 ? 0.656   31.922  46.629  1.00 26.17  ? 171 GLU A CB  1 
ATOM   1226  C  CG  . GLU A 1 171 ? 0.826   31.384  45.205  1.00 25.63  ? 171 GLU A CG  1 
ATOM   1227  C  CD  . GLU A 1 171 ? 1.606   30.085  45.007  1.00 30.99  ? 171 GLU A CD  1 
ATOM   1228  O  OE1 . GLU A 1 171 ? 2.163   29.480  45.957  1.00 26.24  ? 171 GLU A OE1 1 
ATOM   1229  O  OE2 . GLU A 1 171 ? 1.635   29.680  43.845  1.00 36.99  ? 171 GLU A OE2 1 
ATOM   1230  N  N   . ASP A 1 172 ? -1.980  29.648  46.600  1.00 24.69  ? 172 ASP A N   1 
ATOM   1231  C  CA  . ASP A 1 172 ? -3.279  29.374  46.032  1.00 24.23  ? 172 ASP A CA  1 
ATOM   1232  C  C   . ASP A 1 172 ? -3.610  27.940  46.405  1.00 26.64  ? 172 ASP A C   1 
ATOM   1233  O  O   . ASP A 1 172 ? -3.708  27.043  45.564  1.00 28.76  ? 172 ASP A O   1 
ATOM   1234  C  CB  . ASP A 1 172 ? -3.389  29.682  44.547  1.00 26.92  ? 172 ASP A CB  1 
ATOM   1235  C  CG  . ASP A 1 172 ? -4.772  29.570  43.894  1.00 28.11  ? 172 ASP A CG  1 
ATOM   1236  O  OD1 . ASP A 1 172 ? -5.741  29.508  44.659  1.00 27.21  ? 172 ASP A OD1 1 
ATOM   1237  O  OD2 . ASP A 1 172 ? -4.881  29.604  42.632  1.00 25.23  ? 172 ASP A OD2 1 
ATOM   1238  N  N   . PRO A 1 173 ? -3.919  27.710  47.696  1.00 30.82  ? 173 PRO A N   1 
ATOM   1239  C  CA  . PRO A 1 173 ? -3.870  26.358  48.292  1.00 27.94  ? 173 PRO A CA  1 
ATOM   1240  C  C   . PRO A 1 173 ? -4.838  25.346  47.698  1.00 23.50  ? 173 PRO A C   1 
ATOM   1241  O  O   . PRO A 1 173 ? -4.572  24.160  47.650  1.00 23.03  ? 173 PRO A O   1 
ATOM   1242  C  CB  . PRO A 1 173 ? -4.261  26.570  49.743  1.00 27.04  ? 173 PRO A CB  1 
ATOM   1243  C  CG  . PRO A 1 173 ? -4.354  28.053  49.936  1.00 28.10  ? 173 PRO A CG  1 
ATOM   1244  C  CD  . PRO A 1 173 ? -4.409  28.758  48.609  1.00 30.84  ? 173 PRO A CD  1 
ATOM   1245  N  N   . ALA A 1 174 ? -5.982  25.836  47.249  1.00 22.15  ? 174 ALA A N   1 
ATOM   1246  C  CA  . ALA A 1 174 ? -6.933  24.923  46.666  1.00 24.89  ? 174 ALA A CA  1 
ATOM   1247  C  C   . ALA A 1 174 ? -6.395  24.322  45.382  1.00 25.72  ? 174 ALA A C   1 
ATOM   1248  O  O   . ALA A 1 174 ? -6.973  23.352  44.957  1.00 26.04  ? 174 ALA A O   1 
ATOM   1249  C  CB  . ALA A 1 174 ? -8.256  25.602  46.362  1.00 27.12  ? 174 ALA A CB  1 
ATOM   1250  N  N   . PHE A 1 175 ? -5.422  24.960  44.716  1.00 25.93  ? 175 PHE A N   1 
ATOM   1251  C  CA  . PHE A 1 175 ? -4.908  24.469  43.438  1.00 26.00  ? 175 PHE A CA  1 
ATOM   1252  C  C   . PHE A 1 175 ? -3.420  24.087  43.502  1.00 26.94  ? 175 PHE A C   1 
ATOM   1253  O  O   . PHE A 1 175 ? -2.753  23.988  42.484  1.00 26.20  ? 175 PHE A O   1 
ATOM   1254  C  CB  . PHE A 1 175 ? -5.191  25.584  42.433  1.00 25.71  ? 175 PHE A CB  1 
ATOM   1255  C  CG  . PHE A 1 175 ? -6.686  25.738  42.179  1.00 23.36  ? 175 PHE A CG  1 
ATOM   1256  C  CD1 . PHE A 1 175 ? -7.383  24.747  41.514  1.00 26.94  ? 175 PHE A CD1 1 
ATOM   1257  C  CD2 . PHE A 1 175 ? -7.397  26.803  42.697  1.00 25.51  ? 175 PHE A CD2 1 
ATOM   1258  C  CE1 . PHE A 1 175 ? -8.750  24.828  41.339  1.00 26.61  ? 175 PHE A CE1 1 
ATOM   1259  C  CE2 . PHE A 1 175 ? -8.758  26.861  42.546  1.00 26.29  ? 175 PHE A CE2 1 
ATOM   1260  C  CZ  . PHE A 1 175 ? -9.434  25.866  41.881  1.00 25.36  ? 175 PHE A CZ  1 
ATOM   1261  N  N   . ALA A 1 176 ? -2.897  23.910  44.716  1.00 27.67  ? 176 ALA A N   1 
ATOM   1262  C  CA  . ALA A 1 176 ? -1.521  23.497  44.903  1.00 28.24  ? 176 ALA A CA  1 
ATOM   1263  C  C   . ALA A 1 176 ? -1.237  22.244  44.069  1.00 25.35  ? 176 ALA A C   1 
ATOM   1264  O  O   . ALA A 1 176 ? -2.037  21.330  44.004  1.00 24.70  ? 176 ALA A O   1 
ATOM   1265  C  CB  . ALA A 1 176 ? -1.256  23.299  46.385  1.00 27.35  ? 176 ALA A CB  1 
ATOM   1266  N  N   . GLY A 1 177 ? -0.106  22.248  43.348  1.00 24.28  ? 177 GLY A N   1 
ATOM   1267  C  CA  . GLY A 1 177 ? 0.319   21.075  42.586  1.00 22.10  ? 177 GLY A CA  1 
ATOM   1268  C  C   . GLY A 1 177 ? 0.056   21.257  41.108  1.00 21.71  ? 177 GLY A C   1 
ATOM   1269  O  O   . GLY A 1 177 ? 0.542   20.467  40.291  1.00 26.51  ? 177 GLY A O   1 
ATOM   1270  N  N   . GLY A 1 178 ? -0.676  22.335  40.818  1.00 19.33  ? 178 GLY A N   1 
ATOM   1271  C  CA  . GLY A 1 178 ? -0.932  22.770  39.458  1.00 20.69  ? 178 GLY A CA  1 
ATOM   1272  C  C   . GLY A 1 178 ? 0.177   23.671  38.927  1.00 20.67  ? 178 GLY A C   1 
ATOM   1273  O  O   . GLY A 1 178 ? 1.198   23.883  39.621  1.00 21.57  ? 178 GLY A O   1 
ATOM   1274  N  N   . SER A 1 179 ? 0.014   24.045  37.638  1.00 22.97  ? 179 SER A N   1 
ATOM   1275  C  CA  . SER A 1 179 ? 0.977   24.886  36.956  1.00 21.44  ? 179 SER A CA  1 
ATOM   1276  C  C   . SER A 1 179 ? 0.258   25.646  35.860  1.00 19.93  ? 179 SER A C   1 
ATOM   1277  O  O   . SER A 1 179 ? -0.875  25.312  35.545  1.00 20.33  ? 179 SER A O   1 
ATOM   1278  C  CB  . SER A 1 179 ? 2.193   24.116  36.439  1.00 20.68  ? 179 SER A CB  1 
ATOM   1279  O  OG  . SER A 1 179 ? 3.244   25.031  36.083  1.00 20.29  ? 179 SER A OG  1 
ATOM   1280  N  N   . TYR A 1 180 ? 0.918   26.685  35.345  1.00 21.38  ? 180 TYR A N   1 
ATOM   1281  C  CA  . TYR A 1 180 ? 0.418   27.467  34.237  1.00 21.51  ? 180 TYR A CA  1 
ATOM   1282  C  C   . TYR A 1 180 ? 1.339   27.257  33.036  1.00 21.61  ? 180 TYR A C   1 
ATOM   1283  O  O   . TYR A 1 180 ? 2.517   27.537  33.123  1.00 23.48  ? 180 TYR A O   1 
ATOM   1284  C  CB  . TYR A 1 180 ? 0.369   28.963  34.577  1.00 22.82  ? 180 TYR A CB  1 
ATOM   1285  C  CG  . TYR A 1 180 ? -0.654  29.297  35.665  1.00 26.60  ? 180 TYR A CG  1 
ATOM   1286  C  CD1 . TYR A 1 180 ? -0.315  29.228  37.018  1.00 25.38  ? 180 TYR A CD1 1 
ATOM   1287  C  CD2 . TYR A 1 180 ? -1.984  29.634  35.357  1.00 27.82  ? 180 TYR A CD2 1 
ATOM   1288  C  CE1 . TYR A 1 180 ? -1.250  29.508  38.014  1.00 24.58  ? 180 TYR A CE1 1 
ATOM   1289  C  CE2 . TYR A 1 180 ? -2.916  29.915  36.355  1.00 29.80  ? 180 TYR A CE2 1 
ATOM   1290  C  CZ  . TYR A 1 180 ? -2.558  29.873  37.699  1.00 25.80  ? 180 TYR A CZ  1 
ATOM   1291  O  OH  . TYR A 1 180 ? -3.482  30.168  38.680  1.00 22.19  ? 180 TYR A OH  1 
ATOM   1292  N  N   . ALA A 1 181 ? 0.763   26.842  31.909  1.00 21.02  ? 181 ALA A N   1 
ATOM   1293  C  CA  . ALA A 1 181 ? 1.482   26.662  30.671  1.00 19.20  ? 181 ALA A CA  1 
ATOM   1294  C  C   . ALA A 1 181 ? 1.053   27.720  29.672  1.00 22.84  ? 181 ALA A C   1 
ATOM   1295  O  O   . ALA A 1 181 ? -0.141  27.901  29.389  1.00 25.59  ? 181 ALA A O   1 
ATOM   1296  C  CB  . ALA A 1 181 ? 1.159   25.313  30.123  1.00 20.23  ? 181 ALA A CB  1 
ATOM   1297  N  N   . VAL A 1 182 ? 2.068   28.370  29.096  1.00 22.58  ? 182 VAL A N   1 
ATOM   1298  C  CA  . VAL A 1 182 ? 1.897   29.240  27.947  1.00 25.04  ? 182 VAL A CA  1 
ATOM   1299  C  C   . VAL A 1 182 ? 2.496   28.564  26.698  1.00 21.38  ? 182 VAL A C   1 
ATOM   1300  O  O   . VAL A 1 182 ? 3.604   28.071  26.782  1.00 17.75  ? 182 VAL A O   1 
ATOM   1301  C  CB  . VAL A 1 182 ? 2.566   30.579  28.247  1.00 24.86  ? 182 VAL A CB  1 
ATOM   1302  C  CG1 . VAL A 1 182 ? 2.516   31.452  27.031  1.00 27.50  ? 182 VAL A CG1 1 
ATOM   1303  C  CG2 . VAL A 1 182 ? 1.920   31.260  29.430  1.00 28.33  ? 182 VAL A CG2 1 
ATOM   1304  N  N   . VAL A 1 183 ? 1.747   28.571  25.587  1.00 19.98  ? 183 VAL A N   1 
ATOM   1305  C  CA  . VAL A 1 183 ? 2.183   27.988  24.337  1.00 20.39  ? 183 VAL A CA  1 
ATOM   1306  C  C   . VAL A 1 183 ? 2.171   29.088  23.288  1.00 21.84  ? 183 VAL A C   1 
ATOM   1307  O  O   . VAL A 1 183 ? 1.272   29.923  23.269  1.00 19.53  ? 183 VAL A O   1 
ATOM   1308  C  CB  . VAL A 1 183 ? 1.394   26.765  23.859  1.00 23.57  ? 183 VAL A CB  1 
ATOM   1309  C  CG1 . VAL A 1 183 ? 1.465   25.626  24.883  1.00 30.87  ? 183 VAL A CG1 1 
ATOM   1310  C  CG2 . VAL A 1 183 ? -0.045  27.067  23.574  1.00 24.35  ? 183 VAL A CG2 1 
ATOM   1311  N  N   . GLN A 1 184 ? 3.222   29.086  22.470  1.00 17.61  ? 184 GLN A N   1 
ATOM   1312  C  CA  . GLN A 1 184 ? 3.255   29.858  21.256  1.00 19.79  ? 184 GLN A CA  1 
ATOM   1313  C  C   . GLN A 1 184 ? 3.929   29.052  20.138  1.00 20.76  ? 184 GLN A C   1 
ATOM   1314  O  O   . GLN A 1 184 ? 5.036   28.551  20.297  1.00 23.10  ? 184 GLN A O   1 
ATOM   1315  C  CB  . GLN A 1 184 ? 4.061   31.125  21.467  1.00 20.29  ? 184 GLN A CB  1 
ATOM   1316  C  CG  . GLN A 1 184 ? 3.483   32.122  22.436  1.00 19.42  ? 184 GLN A CG  1 
ATOM   1317  C  CD  . GLN A 1 184 ? 4.387   33.307  22.490  1.00 20.72  ? 184 GLN A CD  1 
ATOM   1318  O  OE1 . GLN A 1 184 ? 5.537   33.175  22.906  1.00 21.53  ? 184 GLN A OE1 1 
ATOM   1319  N  NE2 . GLN A 1 184 ? 3.919   34.397  21.902  1.00 23.83  ? 184 GLN A NE2 1 
ATOM   1320  N  N   . LYS A 1 185 ? 3.274   28.932  18.983  1.00 19.47  ? 185 LYS A N   1 
ATOM   1321  C  CA  . LYS A 1 185 ? 3.940   28.391  17.826  1.00 21.59  ? 185 LYS A CA  1 
ATOM   1322  C  C   . LYS A 1 185 ? 4.657   29.511  17.080  1.00 20.11  ? 185 LYS A C   1 
ATOM   1323  O  O   . LYS A 1 185 ? 4.012   30.445  16.649  1.00 23.37  ? 185 LYS A O   1 
ATOM   1324  C  CB  . LYS A 1 185 ? 2.892   27.720  16.947  1.00 23.82  ? 185 LYS A CB  1 
ATOM   1325  C  CG  . LYS A 1 185 ? 3.506   27.210  15.616  1.00 26.99  ? 185 LYS A CG  1 
ATOM   1326  C  CD  . LYS A 1 185 ? 2.749   26.038  15.035  1.00 29.82  ? 185 LYS A CD  1 
ATOM   1327  C  CE  . LYS A 1 185 ? 1.496   26.516  14.478  1.00 31.32  ? 185 LYS A CE  1 
ATOM   1328  N  NZ  . LYS A 1 185 ? 0.819   25.317  13.974  1.00 37.85  ? 185 LYS A NZ  1 
ATOM   1329  N  N   . TYR A 1 186 ? 5.967   29.359  16.881  1.00 19.28  ? 186 TYR A N   1 
ATOM   1330  C  CA  . TYR A 1 186 ? 6.766   30.336  16.159  1.00 21.22  ? 186 TYR A CA  1 
ATOM   1331  C  C   . TYR A 1 186 ? 7.251   29.755  14.839  1.00 21.20  ? 186 TYR A C   1 
ATOM   1332  O  O   . TYR A 1 186 ? 7.712   28.616  14.802  1.00 21.52  ? 186 TYR A O   1 
ATOM   1333  C  CB  . TYR A 1 186 ? 8.042   30.715  16.894  1.00 19.65  ? 186 TYR A CB  1 
ATOM   1334  C  CG  . TYR A 1 186 ? 7.790   31.697  18.015  1.00 20.69  ? 186 TYR A CG  1 
ATOM   1335  C  CD1 . TYR A 1 186 ? 7.792   33.052  17.770  1.00 16.87  ? 186 TYR A CD1 1 
ATOM   1336  C  CD2 . TYR A 1 186 ? 7.550   31.223  19.308  1.00 21.08  ? 186 TYR A CD2 1 
ATOM   1337  C  CE1 . TYR A 1 186 ? 7.634   33.933  18.808  1.00 18.38  ? 186 TYR A CE1 1 
ATOM   1338  C  CE2 . TYR A 1 186 ? 7.293   32.096  20.344  1.00 23.47  ? 186 TYR A CE2 1 
ATOM   1339  C  CZ  . TYR A 1 186 ? 7.364   33.469  20.099  1.00 25.29  ? 186 TYR A CZ  1 
ATOM   1340  O  OH  . TYR A 1 186 ? 7.184   34.334  21.165  1.00 20.34  ? 186 TYR A OH  1 
ATOM   1341  N  N   . LEU A 1 187 ? 7.196   30.584  13.789  1.00 22.94  ? 187 LEU A N   1 
ATOM   1342  C  CA  . LEU A 1 187 ? 7.849   30.231  12.543  1.00 20.84  ? 187 LEU A CA  1 
ATOM   1343  C  C   . LEU A 1 187 ? 9.073   31.118  12.364  1.00 20.41  ? 187 LEU A C   1 
ATOM   1344  O  O   . LEU A 1 187 ? 9.025   32.300  12.667  1.00 21.43  ? 187 LEU A O   1 
ATOM   1345  C  CB  . LEU A 1 187 ? 6.873   30.376  11.384  1.00 22.08  ? 187 LEU A CB  1 
ATOM   1346  C  CG  . LEU A 1 187 ? 5.661   29.442  11.418  1.00 27.32  ? 187 LEU A CG  1 
ATOM   1347  C  CD1 . LEU A 1 187 ? 4.819   29.819  10.248  1.00 26.13  ? 187 LEU A CD1 1 
ATOM   1348  C  CD2 . LEU A 1 187 ? 6.038   27.977  11.324  1.00 28.38  ? 187 LEU A CD2 1 
ATOM   1349  N  N   . HIS A 1 188 ? 10.154  30.549  11.834  1.00 19.70  ? 188 HIS A N   1 
ATOM   1350  C  CA  . HIS A 1 188 ? 11.370  31.297  11.618  1.00 20.49  ? 188 HIS A CA  1 
ATOM   1351  C  C   . HIS A 1 188 ? 11.576  31.577  10.140  1.00 20.43  ? 188 HIS A C   1 
ATOM   1352  O  O   . HIS A 1 188 ? 11.266  30.738  9.299   1.00 21.80  ? 188 HIS A O   1 
ATOM   1353  C  CB  . HIS A 1 188 ? 12.547  30.496  12.119  1.00 18.64  ? 188 HIS A CB  1 
ATOM   1354  C  CG  . HIS A 1 188 ? 12.442  30.210  13.573  1.00 18.00  ? 188 HIS A CG  1 
ATOM   1355  N  ND1 . HIS A 1 188 ? 12.554  31.224  14.482  1.00 17.48  ? 188 HIS A ND1 1 
ATOM   1356  C  CD2 . HIS A 1 188 ? 12.302  29.068  14.272  1.00 18.86  ? 188 HIS A CD2 1 
ATOM   1357  C  CE1 . HIS A 1 188 ? 12.489  30.698  15.713  1.00 18.22  ? 188 HIS A CE1 1 
ATOM   1358  N  NE2 . HIS A 1 188 ? 12.338  29.381  15.612  1.00 17.64  ? 188 HIS A NE2 1 
ATOM   1359  N  N   . ASP A 1 189 ? 12.061  32.788  9.856   1.00 19.69  ? 189 ASP A N   1 
ATOM   1360  C  CA  . ASP A 1 189 ? 12.576  33.170  8.554   1.00 19.35  ? 189 ASP A CA  1 
ATOM   1361  C  C   . ASP A 1 189 ? 14.054  32.778  8.451   1.00 17.07  ? 189 ASP A C   1 
ATOM   1362  O  O   . ASP A 1 189 ? 14.958  33.541  8.732   1.00 17.00  ? 189 ASP A O   1 
ATOM   1363  C  CB  . ASP A 1 189 ? 12.394  34.664  8.360   1.00 21.09  ? 189 ASP A CB  1 
ATOM   1364  C  CG  . ASP A 1 189 ? 12.774  35.161  6.972   1.00 23.53  ? 189 ASP A CG  1 
ATOM   1365  O  OD1 . ASP A 1 189 ? 13.223  34.293  6.155   1.00 24.03  ? 189 ASP A OD1 1 
ATOM   1366  O  OD2 . ASP A 1 189 ? 12.513  36.377  6.688   1.00 22.62  ? 189 ASP A OD2 1 
ATOM   1367  N  N   . ILE A 1 190 ? 14.275  31.548  8.024   1.00 19.89  ? 190 ILE A N   1 
ATOM   1368  C  CA  . ILE A 1 190 ? 15.589  30.929  8.018   1.00 20.40  ? 190 ILE A CA  1 
ATOM   1369  C  C   . ILE A 1 190 ? 16.482  31.608  7.013   1.00 19.67  ? 190 ILE A C   1 
ATOM   1370  O  O   . ILE A 1 190 ? 17.659  31.745  7.293   1.00 21.97  ? 190 ILE A O   1 
ATOM   1371  C  CB  . ILE A 1 190 ? 15.465  29.428  7.772   1.00 22.47  ? 190 ILE A CB  1 
ATOM   1372  C  CG1 . ILE A 1 190 ? 14.802  28.738  8.962   1.00 22.29  ? 190 ILE A CG1 1 
ATOM   1373  C  CG2 . ILE A 1 190 ? 16.850  28.872  7.482   1.00 25.17  ? 190 ILE A CG2 1 
ATOM   1374  C  CD1 . ILE A 1 190 ? 15.594  28.752  10.255  1.00 19.58  ? 190 ILE A CD1 1 
ATOM   1375  N  N   . ASP A 1 191 ? 15.926  32.106  5.893   1.00 20.64  ? 191 ASP A N   1 
ATOM   1376  C  CA  . ASP A 1 191 ? 16.720  32.811  4.889   1.00 19.26  ? 191 ASP A CA  1 
ATOM   1377  C  C   . ASP A 1 191 ? 17.410  34.020  5.498   1.00 17.09  ? 191 ASP A C   1 
ATOM   1378  O  O   . ASP A 1 191 ? 18.576  34.253  5.363   1.00 18.43  ? 191 ASP A O   1 
ATOM   1379  C  CB  . ASP A 1 191 ? 15.913  33.095  3.624   1.00 19.19  ? 191 ASP A CB  1 
ATOM   1380  C  CG  . ASP A 1 191 ? 15.530  31.856  2.842   1.00 21.14  ? 191 ASP A CG  1 
ATOM   1381  O  OD1 . ASP A 1 191 ? 16.361  31.004  2.766   1.00 22.29  ? 191 ASP A OD1 1 
ATOM   1382  O  OD2 . ASP A 1 191 ? 14.368  31.672  2.434   1.00 23.65  ? 191 ASP A OD2 1 
ATOM   1383  N  N   . ALA A 1 192 ? 16.663  34.788  6.223   1.00 18.92  ? 192 ALA A N   1 
ATOM   1384  C  CA  . ALA A 1 192 ? 17.192  35.987  6.816   1.00 18.31  ? 192 ALA A CA  1 
ATOM   1385  C  C   . ALA A 1 192 ? 18.215  35.628  7.874   1.00 20.81  ? 192 ALA A C   1 
ATOM   1386  O  O   . ALA A 1 192 ? 19.245  36.270  7.995   1.00 26.18  ? 192 ALA A O   1 
ATOM   1387  C  CB  . ALA A 1 192 ? 16.033  36.788  7.381   1.00 19.76  ? 192 ALA A CB  1 
ATOM   1388  N  N   . TRP A 1 193 ? 17.910  34.621  8.707   1.00 20.83  ? 193 TRP A N   1 
ATOM   1389  C  CA  . TRP A 1 193 ? 18.766  34.227  9.813   1.00 20.37  ? 193 TRP A CA  1 
ATOM   1390  C  C   . TRP A 1 193 ? 20.135  33.790  9.300   1.00 22.72  ? 193 TRP A C   1 
ATOM   1391  O  O   . TRP A 1 193 ? 21.149  34.177  9.835   1.00 25.67  ? 193 TRP A O   1 
ATOM   1392  C  CB  . TRP A 1 193 ? 18.037  33.111  10.581  1.00 18.70  ? 193 TRP A CB  1 
ATOM   1393  C  CG  . TRP A 1 193 ? 18.819  32.540  11.728  1.00 17.23  ? 193 TRP A CG  1 
ATOM   1394  C  CD1 . TRP A 1 193 ? 19.296  31.279  11.868  1.00 18.48  ? 193 TRP A CD1 1 
ATOM   1395  C  CD2 . TRP A 1 193 ? 19.149  33.205  12.939  1.00 18.94  ? 193 TRP A CD2 1 
ATOM   1396  N  NE1 . TRP A 1 193 ? 19.909  31.098  13.063  1.00 18.80  ? 193 TRP A NE1 1 
ATOM   1397  C  CE2 . TRP A 1 193 ? 19.843  32.274  13.746  1.00 21.73  ? 193 TRP A CE2 1 
ATOM   1398  C  CE3 . TRP A 1 193 ? 18.963  34.511  13.404  1.00 20.61  ? 193 TRP A CE3 1 
ATOM   1399  C  CZ2 . TRP A 1 193 ? 20.304  32.604  15.021  1.00 22.08  ? 193 TRP A CZ2 1 
ATOM   1400  C  CZ3 . TRP A 1 193 ? 19.417  34.825  14.653  1.00 20.68  ? 193 TRP A CZ3 1 
ATOM   1401  C  CH2 . TRP A 1 193 ? 20.067  33.892  15.440  1.00 21.75  ? 193 TRP A CH2 1 
ATOM   1402  N  N   . GLU A 1 194 ? 20.133  32.995  8.241   1.00 26.54  ? 194 GLU A N   1 
ATOM   1403  C  CA  . GLU A 1 194 ? 21.323  32.411  7.681   1.00 25.46  ? 194 GLU A CA  1 
ATOM   1404  C  C   . GLU A 1 194 ? 22.110  33.442  6.919   1.00 23.72  ? 194 GLU A C   1 
ATOM   1405  O  O   . GLU A 1 194 ? 23.231  33.199  6.580   1.00 26.27  ? 194 GLU A O   1 
ATOM   1406  C  CB  . GLU A 1 194 ? 20.975  31.184  6.852   1.00 33.70  ? 194 GLU A CB  1 
ATOM   1407  C  CG  . GLU A 1 194 ? 21.149  29.917  7.697   1.00 48.98  ? 194 GLU A CG  1 
ATOM   1408  C  CD  . GLU A 1 194 ? 20.693  28.671  6.963   1.00 57.53  ? 194 GLU A CD  1 
ATOM   1409  O  OE1 . GLU A 1 194 ? 20.487  28.710  5.734   1.00 61.07  ? 194 GLU A OE1 1 
ATOM   1410  O  OE2 . GLU A 1 194 ? 20.477  27.650  7.643   1.00 70.20  ? 194 GLU A OE2 1 
ATOM   1411  N  N   . GLY A 1 195 ? 21.604  34.637  6.748   1.00 24.20  ? 195 GLY A N   1 
ATOM   1412  C  CA  . GLY A 1 195 ? 22.433  35.659  6.157   1.00 25.06  ? 195 GLY A CA  1 
ATOM   1413  C  C   . GLY A 1 195 ? 23.263  36.412  7.185   1.00 29.30  ? 195 GLY A C   1 
ATOM   1414  O  O   . GLY A 1 195 ? 23.978  37.313  6.829   1.00 32.49  ? 195 GLY A O   1 
ATOM   1415  N  N   . LEU A 1 196 ? 23.034  36.201  8.482   1.00 29.39  ? 196 LEU A N   1 
ATOM   1416  C  CA  . LEU A 1 196 ? 23.869  36.772  9.525   1.00 25.93  ? 196 LEU A CA  1 
ATOM   1417  C  C   . LEU A 1 196 ? 25.125  35.932  9.633   1.00 25.03  ? 196 LEU A C   1 
ATOM   1418  O  O   . LEU A 1 196 ? 25.054  34.735  9.421   1.00 24.24  ? 196 LEU A O   1 
ATOM   1419  C  CB  . LEU A 1 196 ? 23.075  36.753  10.832  1.00 27.73  ? 196 LEU A CB  1 
ATOM   1420  C  CG  . LEU A 1 196 ? 22.298  38.023  11.203  1.00 32.63  ? 196 LEU A CG  1 
ATOM   1421  C  CD1 . LEU A 1 196 ? 21.535  38.651  10.110  1.00 35.90  ? 196 LEU A CD1 1 
ATOM   1422  C  CD2 . LEU A 1 196 ? 21.352  37.772  12.321  1.00 34.40  ? 196 LEU A CD2 1 
ATOM   1423  N  N   . SER A 1 197 ? 26.247  36.547  10.027  1.00 25.63  ? 197 SER A N   1 
ATOM   1424  C  CA  . SER A 1 197 ? 27.422  35.789  10.448  1.00 21.62  ? 197 SER A CA  1 
ATOM   1425  C  C   . SER A 1 197 ? 27.116  35.076  11.756  1.00 23.03  ? 197 SER A C   1 
ATOM   1426  O  O   . SER A 1 197 ? 26.217  35.459  12.501  1.00 22.46  ? 197 SER A O   1 
ATOM   1427  C  CB  . SER A 1 197 ? 28.581  36.698  10.667  1.00 20.89  ? 197 SER A CB  1 
ATOM   1428  O  OG  . SER A 1 197 ? 28.308  37.578  11.777  1.00 24.26  ? 197 SER A OG  1 
ATOM   1429  N  N   . VAL A 1 198 ? 27.925  34.078  12.085  1.00 22.50  ? 198 VAL A N   1 
ATOM   1430  C  CA  . VAL A 1 198 ? 27.743  33.415  13.367  1.00 24.67  ? 198 VAL A CA  1 
ATOM   1431  C  C   . VAL A 1 198 ? 27.848  34.440  14.510  1.00 25.28  ? 198 VAL A C   1 
ATOM   1432  O  O   . VAL A 1 198 ? 27.118  34.308  15.507  1.00 26.82  ? 198 VAL A O   1 
ATOM   1433  C  CB  . VAL A 1 198 ? 28.748  32.263  13.528  1.00 22.98  ? 198 VAL A CB  1 
ATOM   1434  C  CG1 . VAL A 1 198 ? 28.782  31.736  14.962  1.00 26.92  ? 198 VAL A CG1 1 
ATOM   1435  C  CG2 . VAL A 1 198 ? 28.429  31.124  12.613  1.00 22.92  ? 198 VAL A CG2 1 
ATOM   1436  N  N   . GLU A 1 199 ? 28.755  35.432  14.396  1.00 24.47  ? 199 GLU A N   1 
ATOM   1437  C  CA  . GLU A 1 199 ? 29.032  36.339  15.523  1.00 26.75  ? 199 GLU A CA  1 
ATOM   1438  C  C   . GLU A 1 199 ? 27.801  37.206  15.751  1.00 26.07  ? 199 GLU A C   1 
ATOM   1439  O  O   . GLU A 1 199 ? 27.470  37.474  16.896  1.00 28.76  ? 199 GLU A O   1 
ATOM   1440  C  CB  . GLU A 1 199 ? 30.280  37.234  15.429  1.00 33.01  ? 199 GLU A CB  1 
ATOM   1441  C  CG  . GLU A 1 199 ? 31.586  36.422  15.231  1.00 42.56  ? 199 GLU A CG  1 
ATOM   1442  C  CD  . GLU A 1 199 ? 31.831  35.356  14.087  1.00 36.35  ? 199 GLU A CD  1 
ATOM   1443  O  OE1 . GLU A 1 199 ? 31.278  35.507  12.897  1.00 27.84  ? 199 GLU A OE1 1 
ATOM   1444  O  OE2 . GLU A 1 199 ? 32.588  34.351  14.422  1.00 30.65  ? 199 GLU A OE2 1 
ATOM   1445  N  N   . ALA A 1 200 ? 27.089  37.526  14.673  1.00 22.23  ? 200 ALA A N   1 
ATOM   1446  C  CA  . ALA A 1 200 ? 25.877  38.323  14.735  1.00 23.14  ? 200 ALA A CA  1 
ATOM   1447  C  C   . ALA A 1 200 ? 24.745  37.497  15.327  1.00 24.49  ? 200 ALA A C   1 
ATOM   1448  O  O   . ALA A 1 200 ? 23.896  38.032  16.042  1.00 29.82  ? 200 ALA A O   1 
ATOM   1449  C  CB  . ALA A 1 200 ? 25.472  38.827  13.325  1.00 24.25  ? 200 ALA A CB  1 
ATOM   1450  N  N   . GLN A 1 201 ? 24.710  36.211  15.004  1.00 21.12  ? 201 GLN A N   1 
ATOM   1451  C  CA  . GLN A 1 201 ? 23.689  35.358  15.569  1.00 24.24  ? 201 GLN A CA  1 
ATOM   1452  C  C   . GLN A 1 201 ? 23.880  35.245  17.074  1.00 22.52  ? 201 GLN A C   1 
ATOM   1453  O  O   . GLN A 1 201 ? 22.903  35.253  17.827  1.00 25.72  ? 201 GLN A O   1 
ATOM   1454  C  CB  . GLN A 1 201 ? 23.727  33.976  14.920  1.00 26.35  ? 201 GLN A CB  1 
ATOM   1455  C  CG  . GLN A 1 201 ? 23.395  33.947  13.431  1.00 24.19  ? 201 GLN A CG  1 
ATOM   1456  C  CD  . GLN A 1 201 ? 23.359  32.541  12.913  1.00 23.04  ? 201 GLN A CD  1 
ATOM   1457  O  OE1 . GLN A 1 201 ? 23.701  31.559  13.573  1.00 24.65  ? 201 GLN A OE1 1 
ATOM   1458  N  NE2 . GLN A 1 201 ? 22.763  32.405  11.762  1.00 24.76  ? 201 GLN A NE2 1 
ATOM   1459  N  N   . GLU A 1 202 ? 25.124  35.126  17.489  1.00 21.54  ? 202 GLU A N   1 
ATOM   1460  C  CA  . GLU A 1 202 ? 25.410  35.001  18.916  1.00 22.73  ? 202 GLU A CA  1 
ATOM   1461  C  C   . GLU A 1 202 ? 24.970  36.261  19.687  1.00 24.98  ? 202 GLU A C   1 
ATOM   1462  O  O   . GLU A 1 202 ? 24.594  36.189  20.854  1.00 20.29  ? 202 GLU A O   1 
ATOM   1463  C  CB  . GLU A 1 202 ? 26.908  34.741  19.090  1.00 24.02  ? 202 GLU A CB  1 
ATOM   1464  C  CG  . GLU A 1 202 ? 27.363  33.326  18.721  1.00 24.94  ? 202 GLU A CG  1 
ATOM   1465  C  CD  . GLU A 1 202 ? 28.843  33.128  18.654  1.00 24.25  ? 202 GLU A CD  1 
ATOM   1466  O  OE1 . GLU A 1 202 ? 29.575  34.139  18.611  1.00 24.74  ? 202 GLU A OE1 1 
ATOM   1467  O  OE2 . GLU A 1 202 ? 29.216  31.964  18.735  1.00 23.82  ? 202 GLU A OE2 1 
ATOM   1468  N  N   . ARG A 1 203 ? 25.025  37.425  19.019  1.00 24.41  ? 203 ARG A N   1 
ATOM   1469  C  CA  . ARG A 1 203 ? 24.625  38.692  19.600  1.00 27.47  ? 203 ARG A CA  1 
ATOM   1470  C  C   . ARG A 1 203 ? 23.112  38.790  19.683  1.00 23.94  ? 203 ARG A C   1 
ATOM   1471  O  O   . ARG A 1 203 ? 22.573  39.472  20.531  1.00 22.11  ? 203 ARG A O   1 
ATOM   1472  C  CB  . ARG A 1 203 ? 25.340  39.832  18.847  1.00 32.83  ? 203 ARG A CB  1 
ATOM   1473  C  CG  . ARG A 1 203 ? 26.709  40.010  19.544  1.00 41.16  ? 203 ARG A CG  1 
ATOM   1474  C  CD  . ARG A 1 203 ? 27.862  40.895  18.990  1.00 46.18  ? 203 ARG A CD  1 
ATOM   1475  N  NE  . ARG A 1 203 ? 27.276  41.732  17.933  1.00 48.67  ? 203 ARG A NE  1 
ATOM   1476  N  N   . VAL A 1 204 ? 22.415  38.084  18.825  1.00 20.90  ? 204 VAL A N   1 
ATOM   1477  C  CA  . VAL A 1 204 ? 20.964  37.974  18.943  1.00 23.07  ? 204 VAL A CA  1 
ATOM   1478  C  C   . VAL A 1 204 ? 20.556  37.085  20.130  1.00 22.64  ? 204 VAL A C   1 
ATOM   1479  O  O   . VAL A 1 204 ? 19.654  37.414  20.884  1.00 22.03  ? 204 VAL A O   1 
ATOM   1480  C  CB  . VAL A 1 204 ? 20.413  37.482  17.600  1.00 20.79  ? 204 VAL A CB  1 
ATOM   1481  C  CG1 . VAL A 1 204 ? 18.928  37.166  17.705  1.00 22.20  ? 204 VAL A CG1 1 
ATOM   1482  C  CG2 . VAL A 1 204 ? 20.695  38.558  16.568  1.00 22.59  ? 204 VAL A CG2 1 
ATOM   1483  N  N   . ILE A 1 205 ? 21.197  35.933  20.291  1.00 20.77  ? 205 ILE A N   1 
ATOM   1484  C  CA  . ILE A 1 205 ? 20.761  35.000  21.303  1.00 22.34  ? 205 ILE A CA  1 
ATOM   1485  C  C   . ILE A 1 205 ? 21.365  35.393  22.658  1.00 22.59  ? 205 ILE A C   1 
ATOM   1486  O  O   . ILE A 1 205 ? 20.650  35.379  23.648  1.00 24.70  ? 205 ILE A O   1 
ATOM   1487  C  CB  . ILE A 1 205 ? 21.167  33.570  20.901  1.00 25.12  ? 205 ILE A CB  1 
ATOM   1488  C  CG1 . ILE A 1 205 ? 20.532  33.144  19.625  1.00 23.96  ? 205 ILE A CG1 1 
ATOM   1489  C  CG2 . ILE A 1 205 ? 20.910  32.539  22.010  1.00 27.53  ? 205 ILE A CG2 1 
ATOM   1490  C  CD1 . ILE A 1 205 ? 19.038  33.028  19.728  1.00 24.65  ? 205 ILE A CD1 1 
ATOM   1491  N  N   . GLY A 1 206 ? 22.685  35.656  22.706  1.00 20.96  ? 206 GLY A N   1 
ATOM   1492  C  CA  . GLY A 1 206 ? 23.396  35.996  23.919  1.00 20.78  ? 206 GLY A CA  1 
ATOM   1493  C  C   . GLY A 1 206 ? 24.272  34.861  24.426  1.00 22.67  ? 206 GLY A C   1 
ATOM   1494  O  O   . GLY A 1 206 ? 24.815  34.946  25.511  1.00 31.66  ? 206 GLY A O   1 
ATOM   1495  N  N   . ARG A 1 207 ? 24.466  33.826  23.630  1.00 23.09  ? 207 ARG A N   1 
ATOM   1496  C  CA  . ARG A 1 207 ? 25.372  32.749  23.975  1.00 22.53  ? 207 ARG A CA  1 
ATOM   1497  C  C   . ARG A 1 207 ? 26.173  32.372  22.738  1.00 23.11  ? 207 ARG A C   1 
ATOM   1498  O  O   . ARG A 1 207 ? 25.821  32.710  21.636  1.00 23.77  ? 207 ARG A O   1 
ATOM   1499  C  CB  . ARG A 1 207 ? 24.553  31.526  24.407  1.00 23.82  ? 207 ARG A CB  1 
ATOM   1500  C  CG  . ARG A 1 207 ? 23.515  31.834  25.478  1.00 22.45  ? 207 ARG A CG  1 
ATOM   1501  C  CD  . ARG A 1 207 ? 22.817  30.575  25.948  1.00 22.32  ? 207 ARG A CD  1 
ATOM   1502  N  NE  . ARG A 1 207 ? 23.658  29.596  26.657  1.00 26.21  ? 207 ARG A NE  1 
ATOM   1503  C  CZ  . ARG A 1 207 ? 23.922  29.571  27.963  1.00 29.19  ? 207 ARG A CZ  1 
ATOM   1504  N  NH1 . ARG A 1 207 ? 23.361  30.397  28.790  1.00 32.57  ? 207 ARG A NH1 1 
ATOM   1505  N  NH2 . ARG A 1 207 ? 24.657  28.646  28.505  1.00 28.81  ? 207 ARG A NH2 1 
ATOM   1506  N  N   . ARG A 1 208 ? 27.219  31.588  22.912  1.00 23.45  ? 208 ARG A N   1 
ATOM   1507  C  CA  . ARG A 1 208 ? 28.054  31.158  21.808  1.00 25.77  ? 208 ARG A CA  1 
ATOM   1508  C  C   . ARG A 1 208 ? 27.367  30.000  21.112  1.00 24.23  ? 208 ARG A C   1 
ATOM   1509  O  O   . ARG A 1 208 ? 26.744  29.163  21.762  1.00 27.55  ? 208 ARG A O   1 
ATOM   1510  C  CB  . ARG A 1 208 ? 29.405  30.623  22.322  1.00 28.79  ? 208 ARG A CB  1 
ATOM   1511  C  CG  . ARG A 1 208 ? 30.286  31.646  23.016  1.00 27.17  ? 208 ARG A CG  1 
ATOM   1512  C  CD  . ARG A 1 208 ? 30.597  32.900  22.220  1.00 34.37  ? 208 ARG A CD  1 
ATOM   1513  N  NE  . ARG A 1 208 ? 31.331  32.652  20.981  1.00 45.33  ? 208 ARG A NE  1 
ATOM   1514  C  CZ  . ARG A 1 208 ? 32.600  32.226  20.927  1.00 49.61  ? 208 ARG A CZ  1 
ATOM   1515  N  NH1 . ARG A 1 208 ? 33.067  31.657  19.828  1.00 43.08  ? 208 ARG A NH1 1 
ATOM   1516  N  NH2 . ARG A 1 208 ? 33.365  32.305  22.012  1.00 54.73  ? 208 ARG A NH2 1 
ATOM   1517  N  N   . LYS A 1 209 ? 27.552  29.912  19.792  1.00 23.03  ? 209 LYS A N   1 
ATOM   1518  C  CA  . LYS A 1 209 ? 26.787  28.919  19.031  1.00 23.02  ? 209 LYS A CA  1 
ATOM   1519  C  C   . LYS A 1 209 ? 27.324  27.508  19.278  1.00 23.05  ? 209 LYS A C   1 
ATOM   1520  O  O   . LYS A 1 209 ? 26.533  26.639  19.651  1.00 24.52  ? 209 LYS A O   1 
ATOM   1521  C  CB  . LYS A 1 209 ? 26.694  29.340  17.558  1.00 24.40  ? 209 LYS A CB  1 
ATOM   1522  C  CG  . LYS A 1 209 ? 25.715  28.553  16.790  1.00 24.98  ? 209 LYS A CG  1 
ATOM   1523  C  CD  . LYS A 1 209 ? 25.507  29.106  15.383  1.00 27.45  ? 209 LYS A CD  1 
ATOM   1524  C  CE  . LYS A 1 209 ? 24.261  28.442  14.827  1.00 29.82  ? 209 LYS A CE  1 
ATOM   1525  N  NZ  . LYS A 1 209 ? 24.035  28.815  13.427  1.00 29.61  ? 209 LYS A NZ  1 
ATOM   1526  N  N   . MET A 1 210 ? 28.635  27.272  19.046  1.00 24.87  ? 210 MET A N   1 
ATOM   1527  C  CA  . MET A 1 210 ? 29.084  25.874  19.030  1.00 27.07  ? 210 MET A CA  1 
ATOM   1528  C  C   . MET A 1 210 ? 29.199  25.398  20.467  1.00 25.93  ? 210 MET A C   1 
ATOM   1529  O  O   . MET A 1 210 ? 28.644  24.369  20.773  1.00 32.75  ? 210 MET A O   1 
ATOM   1530  C  CB  . MET A 1 210 ? 30.315  25.428  18.206  1.00 31.34  ? 210 MET A CB  1 
ATOM   1531  C  CG  . MET A 1 210 ? 30.431  25.892  16.638  1.00 44.68  ? 210 MET A CG  1 
ATOM   1532  S  SD  . MET A 1 210 ? 29.283  26.033  15.186  1.00 57.75  ? 210 MET A SD  1 
ATOM   1533  C  CE  . MET A 1 210 ? 28.597  24.372  15.090  1.00 62.45  ? 210 MET A CE  1 
ATOM   1534  N  N   . THR A 1 211 ? 29.730  26.188  21.389  1.00 25.64  ? 211 THR A N   1 
ATOM   1535  C  CA  . THR A 1 211 ? 30.028  25.743  22.745  1.00 26.38  ? 211 THR A CA  1 
ATOM   1536  C  C   . THR A 1 211 ? 28.912  26.025  23.755  1.00 26.91  ? 211 THR A C   1 
ATOM   1537  O  O   . THR A 1 211 ? 28.983  25.548  24.875  1.00 26.31  ? 211 THR A O   1 
ATOM   1538  C  CB  . THR A 1 211 ? 31.323  26.416  23.202  1.00 28.88  ? 211 THR A CB  1 
ATOM   1539  O  OG1 . THR A 1 211 ? 31.107  27.821  23.297  1.00 29.92  ? 211 THR A OG1 1 
ATOM   1540  C  CG2 . THR A 1 211 ? 32.468  26.145  22.246  1.00 34.38  ? 211 THR A CG2 1 
ATOM   1541  N  N   . ASP A 1 212 ? 27.905  26.828  23.410  1.00 24.07  ? 212 ASP A N   1 
ATOM   1542  C  CA  . ASP A 1 212 ? 26.825  27.144  24.336  1.00 24.29  ? 212 ASP A CA  1 
ATOM   1543  C  C   . ASP A 1 212 ? 27.318  27.833  25.611  1.00 23.44  ? 212 ASP A C   1 
ATOM   1544  O  O   . ASP A 1 212 ? 26.686  27.760  26.638  1.00 26.45  ? 212 ASP A O   1 
ATOM   1545  C  CB  . ASP A 1 212 ? 26.011  25.929  24.738  1.00 24.23  ? 212 ASP A CB  1 
ATOM   1546  C  CG  . ASP A 1 212 ? 24.602  26.204  25.274  1.00 24.88  ? 212 ASP A CG  1 
ATOM   1547  O  OD1 . ASP A 1 212 ? 24.024  27.335  25.007  1.00 22.08  ? 212 ASP A OD1 1 
ATOM   1548  O  OD2 . ASP A 1 212 ? 24.080  25.248  25.897  1.00 27.41  ? 212 ASP A OD2 1 
ATOM   1549  N  N   . VAL A 1 213 ? 28.395  28.574  25.555  1.00 25.04  ? 213 VAL A N   1 
ATOM   1550  C  CA  . VAL A 1 213 ? 28.800  29.336  26.713  1.00 24.17  ? 213 VAL A CA  1 
ATOM   1551  C  C   . VAL A 1 213 ? 28.162  30.709  26.635  1.00 27.90  ? 213 VAL A C   1 
ATOM   1552  O  O   . VAL A 1 213 ? 28.218  31.363  25.598  1.00 25.81  ? 213 VAL A O   1 
ATOM   1553  C  CB  . VAL A 1 213 ? 30.331  29.435  26.784  1.00 26.73  ? 213 VAL A CB  1 
ATOM   1554  C  CG1 . VAL A 1 213 ? 30.774  30.367  27.911  1.00 24.95  ? 213 VAL A CG1 1 
ATOM   1555  C  CG2 . VAL A 1 213 ? 30.947  28.031  26.929  1.00 26.99  ? 213 VAL A CG2 1 
ATOM   1556  N  N   . GLU A 1 214 ? 27.609  31.194  27.760  1.00 24.99  ? 214 GLU A N   1 
ATOM   1557  C  CA  . GLU A 1 214 ? 26.999  32.509  27.783  1.00 26.63  ? 214 GLU A CA  1 
ATOM   1558  C  C   . GLU A 1 214 ? 28.019  33.595  27.445  1.00 24.12  ? 214 GLU A C   1 
ATOM   1559  O  O   . GLU A 1 214 ? 29.150  33.497  27.821  1.00 26.45  ? 214 GLU A O   1 
ATOM   1560  C  CB  . GLU A 1 214 ? 26.413  32.663  29.184  1.00 32.71  ? 214 GLU A CB  1 
ATOM   1561  C  CG  . GLU A 1 214 ? 25.663  33.969  29.410  1.00 36.00  ? 214 GLU A CG  1 
ATOM   1562  C  CD  . GLU A 1 214 ? 24.782  33.893  30.644  1.00 38.53  ? 214 GLU A CD  1 
ATOM   1563  O  OE1 . GLU A 1 214 ? 24.618  32.893  31.368  1.00 46.86  ? 214 GLU A OE1 1 
ATOM   1564  O  OE2 . GLU A 1 214 ? 24.156  34.904  30.793  1.00 34.76  ? 214 GLU A OE2 1 
ATOM   1565  N  N   . LEU A 1 215 ? 27.639  34.610  26.696  1.00 24.37  ? 215 LEU A N   1 
ATOM   1566  C  CA  . LEU A 1 215 ? 28.485  35.756  26.477  1.00 26.37  ? 215 LEU A CA  1 
ATOM   1567  C  C   . LEU A 1 215 ? 28.655  36.457  27.823  1.00 35.01  ? 215 LEU A C   1 
ATOM   1568  O  O   . LEU A 1 215 ? 27.758  36.494  28.671  1.00 34.54  ? 215 LEU A O   1 
ATOM   1569  C  CB  . LEU A 1 215 ? 27.886  36.701  25.428  1.00 29.10  ? 215 LEU A CB  1 
ATOM   1570  C  CG  . LEU A 1 215 ? 27.748  36.194  23.975  1.00 27.37  ? 215 LEU A CG  1 
ATOM   1571  C  CD1 . LEU A 1 215 ? 27.317  37.304  23.047  1.00 26.90  ? 215 LEU A CD1 1 
ATOM   1572  C  CD2 . LEU A 1 215 ? 29.019  35.677  23.462  1.00 27.85  ? 215 LEU A CD2 1 
ATOM   1573  N  N   . SER A 1 216 ? 29.816  37.086  28.024  1.00 35.45  ? 216 SER A N   1 
ATOM   1574  C  CA  . SER A 1 216 ? 30.062  37.772  29.273  1.00 33.98  ? 216 SER A CA  1 
ATOM   1575  C  C   . SER A 1 216 ? 29.258  39.058  29.293  1.00 37.73  ? 216 SER A C   1 
ATOM   1576  O  O   . SER A 1 216 ? 28.926  39.614  28.247  1.00 39.91  ? 216 SER A O   1 
ATOM   1577  C  CB  . SER A 1 216 ? 31.506  38.036  29.419  1.00 39.43  ? 216 SER A CB  1 
ATOM   1578  O  OG  . SER A 1 216 ? 31.935  38.802  28.310  1.00 46.00  ? 216 SER A OG  1 
ATOM   1579  N  N   . ASP A 1 217 ? 29.027  39.560  30.510  1.00 62.52  ? 217 ASP A N   1 
ATOM   1580  C  CA  . ASP A 1 217 ? 28.117  40.676  30.779  1.00 57.24  ? 217 ASP A CA  1 
ATOM   1581  C  C   . ASP A 1 217 ? 28.595  41.928  30.080  1.00 53.52  ? 217 ASP A C   1 
ATOM   1582  O  O   . ASP A 1 217 ? 27.775  42.719  29.665  1.00 57.10  ? 217 ASP A O   1 
ATOM   1583  C  CB  . ASP A 1 217 ? 27.838  40.829  32.262  1.00 60.81  ? 217 ASP A CB  1 
ATOM   1584  C  CG  . ASP A 1 217 ? 27.054  39.627  32.816  1.00 77.26  ? 217 ASP A CG  1 
ATOM   1585  O  OD1 . ASP A 1 217 ? 25.998  39.245  32.230  1.00 66.89  ? 217 ASP A OD1 1 
ATOM   1586  O  OD2 . ASP A 1 217 ? 27.517  39.000  33.800  1.00 92.10  ? 217 ASP A OD2 1 
ATOM   1587  N  N   . ASP A 1 218 ? 29.895  42.062  29.846  1.00 56.68  ? 218 ASP A N   1 
ATOM   1588  C  CA  . ASP A 1 218 ? 30.372  43.247  29.161  1.00 59.78  ? 218 ASP A CA  1 
ATOM   1589  C  C   . ASP A 1 218 ? 30.236  43.108  27.637  1.00 63.94  ? 218 ASP A C   1 
ATOM   1590  O  O   . ASP A 1 218 ? 30.510  44.060  26.923  1.00 64.10  ? 218 ASP A O   1 
ATOM   1591  C  CB  . ASP A 1 218 ? 31.755  43.654  29.650  1.00 64.10  ? 218 ASP A CB  1 
ATOM   1592  C  CG  . ASP A 1 218 ? 32.692  42.480  29.635  1.00 71.27  ? 218 ASP A CG  1 
ATOM   1593  O  OD1 . ASP A 1 218 ? 32.464  41.614  30.499  1.00 97.88  ? 218 ASP A OD1 1 
ATOM   1594  O  OD2 . ASP A 1 218 ? 33.492  42.379  28.680  1.00 79.68  ? 218 ASP A OD2 1 
ATOM   1595  N  N   . VAL A 1 219 ? 29.844  41.972  27.046  1.00 65.18  ? 219 VAL A N   1 
ATOM   1596  C  CA  . VAL A 1 219 ? 29.641  42.012  25.591  1.00 52.37  ? 219 VAL A CA  1 
ATOM   1597  C  C   . VAL A 1 219 ? 28.205  41.641  25.231  1.00 46.56  ? 219 VAL A C   1 
ATOM   1598  O  O   . VAL A 1 219 ? 27.798  41.841  24.104  1.00 46.94  ? 219 VAL A O   1 
ATOM   1599  C  CB  . VAL A 1 219 ? 30.656  41.181  24.774  1.00 52.14  ? 219 VAL A CB  1 
ATOM   1600  C  CG1 . VAL A 1 219 ? 32.036  41.324  25.398  1.00 60.94  ? 219 VAL A CG1 1 
ATOM   1601  C  CG2 . VAL A 1 219 ? 30.313  39.698  24.691  1.00 51.83  ? 219 VAL A CG2 1 
ATOM   1602  N  N   . LYS A 1 220 ? 27.429  41.110  26.163  1.00 39.90  ? 220 LYS A N   1 
ATOM   1603  C  CA  . LYS A 1 220 ? 26.130  40.602  25.793  1.00 35.66  ? 220 LYS A CA  1 
ATOM   1604  C  C   . LYS A 1 220 ? 25.188  41.754  25.583  1.00 30.40  ? 220 LYS A C   1 
ATOM   1605  O  O   . LYS A 1 220 ? 24.956  42.503  26.505  1.00 35.54  ? 220 LYS A O   1 
ATOM   1606  C  CB  . LYS A 1 220 ? 25.610  39.796  26.977  1.00 40.79  ? 220 LYS A CB  1 
ATOM   1607  C  CG  . LYS A 1 220 ? 24.262  39.130  26.718  1.00 43.01  ? 220 LYS A CG  1 
ATOM   1608  C  CD  . LYS A 1 220 ? 23.681  38.436  27.933  1.00 43.43  ? 220 LYS A CD  1 
ATOM   1609  C  CE  . LYS A 1 220 ? 24.746  37.887  28.751  1.00 45.38  ? 220 LYS A CE  1 
ATOM   1610  N  NZ  . LYS A 1 220 ? 24.089  37.323  29.911  1.00 50.83  ? 220 LYS A NZ  1 
ATOM   1611  N  N   . PRO A 1 221 ? 24.607  41.958  24.402  1.00 29.53  ? 221 PRO A N   1 
ATOM   1612  C  CA  . PRO A 1 221 ? 23.707  43.092  24.190  1.00 29.59  ? 221 PRO A CA  1 
ATOM   1613  C  C   . PRO A 1 221 ? 22.440  43.058  25.046  1.00 36.53  ? 221 PRO A C   1 
ATOM   1614  O  O   . PRO A 1 221 ? 21.902  41.981  25.381  1.00 37.00  ? 221 PRO A O   1 
ATOM   1615  C  CB  . PRO A 1 221 ? 23.340  43.027  22.724  1.00 29.01  ? 221 PRO A CB  1 
ATOM   1616  C  CG  . PRO A 1 221 ? 24.389  42.132  22.112  1.00 31.44  ? 221 PRO A CG  1 
ATOM   1617  C  CD  . PRO A 1 221 ? 24.824  41.168  23.195  1.00 32.48  ? 221 PRO A CD  1 
ATOM   1618  N  N   . ALA A 1 222 ? 21.946  44.273  25.320  1.00 35.91  ? 222 ALA A N   1 
ATOM   1619  C  CA  . ALA A 1 222 ? 20.725  44.486  26.069  1.00 35.68  ? 222 ALA A CA  1 
ATOM   1620  C  C   . ALA A 1 222 ? 19.506  43.938  25.342  1.00 31.72  ? 222 ALA A C   1 
ATOM   1621  O  O   . ALA A 1 222 ? 18.508  43.682  26.008  1.00 30.14  ? 222 ALA A O   1 
ATOM   1622  C  CB  . ALA A 1 222 ? 20.547  45.975  26.240  1.00 36.56  ? 222 ALA A CB  1 
ATOM   1623  N  N   . ASP A 1 223 ? 19.556  43.850  23.998  1.00 32.19  ? 223 ASP A N   1 
ATOM   1624  C  CA  . ASP A 1 223 ? 18.411  43.364  23.231  1.00 31.16  ? 223 ASP A CA  1 
ATOM   1625  C  C   . ASP A 1 223 ? 18.598  41.892  22.777  1.00 26.00  ? 223 ASP A C   1 
ATOM   1626  O  O   . ASP A 1 223 ? 17.818  41.382  21.941  1.00 24.65  ? 223 ASP A O   1 
ATOM   1627  C  CB  . ASP A 1 223 ? 18.054  44.288  22.079  1.00 33.12  ? 223 ASP A CB  1 
ATOM   1628  C  CG  . ASP A 1 223 ? 19.119  44.428  21.001  1.00 30.72  ? 223 ASP A CG  1 
ATOM   1629  O  OD1 . ASP A 1 223 ? 20.282  43.975  21.248  1.00 29.26  ? 223 ASP A OD1 1 
ATOM   1630  O  OD2 . ASP A 1 223 ? 18.762  45.035  19.968  1.00 33.97  ? 223 ASP A OD2 1 
ATOM   1631  N  N   . SER A 1 224 ? 19.557  41.195  23.393  1.00 20.13  ? 224 SER A N   1 
ATOM   1632  C  CA  . SER A 1 224 ? 19.674  39.777  23.141  1.00 21.76  ? 224 SER A CA  1 
ATOM   1633  C  C   . SER A 1 224 ? 18.605  39.036  23.931  1.00 24.27  ? 224 SER A C   1 
ATOM   1634  O  O   . SER A 1 224 ? 18.110  39.528  24.942  1.00 24.85  ? 224 SER A O   1 
ATOM   1635  C  CB  . SER A 1 224 ? 21.025  39.286  23.524  1.00 24.45  ? 224 SER A CB  1 
ATOM   1636  O  OG  . SER A 1 224 ? 21.179  39.345  24.943  1.00 24.49  ? 224 SER A OG  1 
ATOM   1637  N  N   . HIS A 1 225 ? 18.301  37.824  23.480  1.00 21.64  ? 225 HIS A N   1 
ATOM   1638  C  CA  . HIS A 1 225 ? 17.207  37.035  24.010  1.00 22.74  ? 225 HIS A CA  1 
ATOM   1639  C  C   . HIS A 1 225 ? 17.441  36.699  25.484  1.00 24.92  ? 225 HIS A C   1 
ATOM   1640  O  O   . HIS A 1 225 ? 16.510  36.782  26.316  1.00 23.00  ? 225 HIS A O   1 
ATOM   1641  C  CB  . HIS A 1 225 ? 17.006  35.799  23.137  1.00 22.86  ? 225 HIS A CB  1 
ATOM   1642  C  CG  . HIS A 1 225 ? 15.943  34.895  23.609  1.00 20.41  ? 225 HIS A CG  1 
ATOM   1643  N  ND1 . HIS A 1 225 ? 14.645  35.300  23.677  1.00 20.08  ? 225 HIS A ND1 1 
ATOM   1644  C  CD2 . HIS A 1 225 ? 15.971  33.595  23.923  1.00 20.72  ? 225 HIS A CD2 1 
ATOM   1645  C  CE1 . HIS A 1 225 ? 13.904  34.254  24.060  1.00 19.90  ? 225 HIS A CE1 1 
ATOM   1646  N  NE2 . HIS A 1 225 ? 14.699  33.206  24.224  1.00 19.09  ? 225 HIS A NE2 1 
ATOM   1647  N  N   . VAL A 1 226 ? 18.683  36.327  25.783  1.00 21.77  ? 226 VAL A N   1 
ATOM   1648  C  CA  . VAL A 1 226 ? 19.033  35.946  27.124  1.00 25.80  ? 226 VAL A CA  1 
ATOM   1649  C  C   . VAL A 1 226 ? 18.987  37.160  28.050  1.00 26.59  ? 226 VAL A C   1 
ATOM   1650  O  O   . VAL A 1 226 ? 18.691  37.055  29.230  1.00 26.09  ? 226 VAL A O   1 
ATOM   1651  C  CB  . VAL A 1 226 ? 20.415  35.268  27.102  1.00 31.77  ? 226 VAL A CB  1 
ATOM   1652  C  CG1 . VAL A 1 226 ? 21.084  35.368  28.457  1.00 37.54  ? 226 VAL A CG1 1 
ATOM   1653  C  CG2 . VAL A 1 226 ? 20.282  33.813  26.633  1.00 27.38  ? 226 VAL A CG2 1 
ATOM   1654  N  N   . ALA A 1 227 ? 19.358  38.311  27.542  1.00 26.72  ? 227 ALA A N   1 
ATOM   1655  C  CA  . ALA A 1 227 ? 19.279  39.513  28.358  1.00 26.99  ? 227 ALA A CA  1 
ATOM   1656  C  C   . ALA A 1 227 ? 17.823  39.816  28.720  1.00 25.21  ? 227 ALA A C   1 
ATOM   1657  O  O   . ALA A 1 227 ? 17.519  40.047  29.866  1.00 25.09  ? 227 ALA A O   1 
ATOM   1658  C  CB  . ALA A 1 227 ? 19.911  40.688  27.621  1.00 27.85  ? 227 ALA A CB  1 
ATOM   1659  N  N   . LEU A 1 228 ? 16.912  39.784  27.753  1.00 22.25  ? 228 LEU A N   1 
ATOM   1660  C  CA  . LEU A 1 228 ? 15.560  40.216  27.999  1.00 21.43  ? 228 LEU A CA  1 
ATOM   1661  C  C   . LEU A 1 228 ? 14.775  39.171  28.771  1.00 23.09  ? 228 LEU A C   1 
ATOM   1662  O  O   . LEU A 1 228 ? 13.810  39.548  29.404  1.00 25.66  ? 228 LEU A O   1 
ATOM   1663  C  CB  . LEU A 1 228 ? 14.881  40.568  26.702  1.00 23.29  ? 228 LEU A CB  1 
ATOM   1664  C  CG  . LEU A 1 228 ? 15.377  41.845  26.039  1.00 34.37  ? 228 LEU A CG  1 
ATOM   1665  C  CD1 . LEU A 1 228 ? 14.835  41.922  24.622  1.00 38.05  ? 228 LEU A CD1 1 
ATOM   1666  C  CD2 . LEU A 1 228 ? 14.900  43.075  26.793  1.00 36.36  ? 228 LEU A CD2 1 
ATOM   1667  N  N   . THR A 1 229 ? 15.140  37.887  28.750  1.00 22.74  ? 229 THR A N   1 
ATOM   1668  C  CA  . THR A 1 229 ? 14.377  36.870  29.460  1.00 24.93  ? 229 THR A CA  1 
ATOM   1669  C  C   . THR A 1 229 ? 15.028  36.533  30.812  1.00 27.61  ? 229 THR A C   1 
ATOM   1670  O  O   . THR A 1 229 ? 14.631  35.586  31.448  1.00 27.92  ? 229 THR A O   1 
ATOM   1671  C  CB  . THR A 1 229 ? 14.227  35.627  28.598  1.00 25.95  ? 229 THR A CB  1 
ATOM   1672  O  OG1 . THR A 1 229 ? 15.511  35.081  28.296  1.00 23.44  ? 229 THR A OG1 1 
ATOM   1673  C  CG2 . THR A 1 229 ? 13.427  35.914  27.329  1.00 25.37  ? 229 THR A CG2 1 
ATOM   1674  N  N   . SER A 1 230 ? 16.040  37.275  31.238  1.00 29.58  ? 230 SER A N   1 
ATOM   1675  C  CA  . SER A 1 230 ? 16.553  37.223  32.594  1.00 34.78  ? 230 SER A CA  1 
ATOM   1676  C  C   . SER A 1 230 ? 15.831  38.267  33.428  1.00 36.84  ? 230 SER A C   1 
ATOM   1677  O  O   . SER A 1 230 ? 15.836  39.444  33.100  1.00 40.74  ? 230 SER A O   1 
ATOM   1678  C  CB  . SER A 1 230 ? 18.023  37.502  32.627  1.00 38.73  ? 230 SER A CB  1 
ATOM   1679  O  OG  . SER A 1 230 ? 18.661  36.421  31.983  1.00 35.39  ? 230 SER A OG  1 
ATOM   1680  N  N   . VAL A 1 231 ? 15.143  37.835  34.472  1.00 34.42  ? 231 VAL A N   1 
ATOM   1681  C  CA  . VAL A 1 231 ? 14.299  38.745  35.226  1.00 38.24  ? 231 VAL A CA  1 
ATOM   1682  C  C   . VAL A 1 231 ? 14.592  38.441  36.674  1.00 33.88  ? 231 VAL A C   1 
ATOM   1683  O  O   . VAL A 1 231 ? 14.580  37.288  37.035  1.00 33.26  ? 231 VAL A O   1 
ATOM   1684  C  CB  . VAL A 1 231 ? 12.797  38.520  34.987  1.00 45.63  ? 231 VAL A CB  1 
ATOM   1685  C  CG1 . VAL A 1 231 ? 11.969  39.548  35.743  1.00 54.39  ? 231 VAL A CG1 1 
ATOM   1686  C  CG2 . VAL A 1 231 ? 12.442  38.479  33.514  1.00 38.02  ? 231 VAL A CG2 1 
ATOM   1687  N  N   . THR A 1 232 ? 14.922  39.458  37.486  1.00 43.19  ? 232 THR A N   1 
ATOM   1688  C  CA  . THR A 1 232 ? 15.045  39.244  38.928  1.00 47.67  ? 232 THR A CA  1 
ATOM   1689  C  C   . THR A 1 232 ? 13.843  39.893  39.633  1.00 43.46  ? 232 THR A C   1 
ATOM   1690  O  O   . THR A 1 232 ? 13.248  40.853  39.126  1.00 36.41  ? 232 THR A O   1 
ATOM   1691  C  CB  . THR A 1 232 ? 16.398  39.735  39.433  1.00 47.71  ? 232 THR A CB  1 
ATOM   1692  O  OG1 . THR A 1 232 ? 16.060  41.027  38.946  1.00 43.33  ? 232 THR A OG1 1 
ATOM   1693  C  CG2 . THR A 1 232 ? 17.565  38.952  38.845  1.00 50.35  ? 232 THR A CG2 1 
ATOM   1694  N  N   . GLY A 1 233 ? 13.438  39.284  40.758  1.00 45.12  ? 233 GLY A N   1 
ATOM   1695  C  CA  . GLY A 1 233 ? 12.250  39.698  41.504  1.00 52.80  ? 233 GLY A CA  1 
ATOM   1696  C  C   . GLY A 1 233 ? 12.605  40.771  42.536  1.00 58.02  ? 233 GLY A C   1 
ATOM   1697  O  O   . GLY A 1 233 ? 13.787  41.133  42.682  1.00 41.04  ? 233 GLY A O   1 
ATOM   1698  N  N   . PRO A 1 234 ? 11.614  41.349  43.274  1.00 54.74  ? 234 PRO A N   1 
ATOM   1699  C  CA  . PRO A 1 234 ? 11.916  42.517  44.111  1.00 49.30  ? 234 PRO A CA  1 
ATOM   1700  C  C   . PRO A 1 234 ? 12.944  42.104  45.164  1.00 45.02  ? 234 PRO A C   1 
ATOM   1701  O  O   . PRO A 1 234 ? 13.856  42.848  45.448  1.00 46.33  ? 234 PRO A O   1 
ATOM   1702  C  CB  . PRO A 1 234 ? 10.579  43.013  44.620  1.00 60.02  ? 234 PRO A CB  1 
ATOM   1703  C  CG  . PRO A 1 234 ? 9.583   42.423  43.574  1.00 72.14  ? 234 PRO A CG  1 
ATOM   1704  C  CD  . PRO A 1 234 ? 10.180  41.027  43.231  1.00 57.42  ? 234 PRO A CD  1 
ATOM   1705  N  N   . ASP A 1 235 ? 12.975  40.854  45.614  1.00 48.54  ? 235 ASP A N   1 
ATOM   1706  C  CA  . ASP A 1 235 ? 14.042  40.459  46.540  1.00 54.72  ? 235 ASP A CA  1 
ATOM   1707  C  C   . ASP A 1 235 ? 15.373  40.038  45.917  1.00 52.56  ? 235 ASP A C   1 
ATOM   1708  O  O   . ASP A 1 235 ? 16.221  39.535  46.638  1.00 52.14  ? 235 ASP A O   1 
ATOM   1709  C  CB  . ASP A 1 235 ? 13.617  39.299  47.422  1.00 76.04  ? 235 ASP A CB  1 
ATOM   1710  C  CG  . ASP A 1 235 ? 13.117  38.078  46.673  1.00 82.81  ? 235 ASP A CG  1 
ATOM   1711  O  OD1 . ASP A 1 235 ? 13.995  37.365  46.060  1.00 74.99  ? 235 ASP A OD1 1 
ATOM   1712  O  OD2 . ASP A 1 235 ? 11.854  37.891  46.748  1.00 49.65  ? 235 ASP A OD2 1 
ATOM   1713  N  N   . GLY A 1 236 ? 15.573  40.164  44.595  1.00 55.35  ? 236 GLY A N   1 
ATOM   1714  C  CA  . GLY A 1 236 ? 16.858  39.837  43.992  1.00 45.32  ? 236 GLY A CA  1 
ATOM   1715  C  C   . GLY A 1 236 ? 16.963  38.390  43.479  1.00 48.34  ? 236 GLY A C   1 
ATOM   1716  O  O   . GLY A 1 236 ? 17.889  38.092  42.715  1.00 53.96  ? 236 GLY A O   1 
ATOM   1717  N  N   . SER A 1 237 ? 16.037  37.469  43.822  1.00 54.73  ? 237 SER A N   1 
ATOM   1718  C  CA  . SER A 1 237 ? 16.110  36.102  43.295  1.00 53.18  ? 237 SER A CA  1 
ATOM   1719  C  C   . SER A 1 237 ? 15.692  36.038  41.809  1.00 42.80  ? 237 SER A C   1 
ATOM   1720  O  O   . SER A 1 237 ? 14.968  36.869  41.268  1.00 32.93  ? 237 SER A O   1 
ATOM   1721  C  CB  . SER A 1 237 ? 15.365  35.093  44.159  1.00 55.69  ? 237 SER A CB  1 
ATOM   1722  O  OG  . SER A 1 237 ? 13.979  35.384  44.247  1.00 55.27  ? 237 SER A OG  1 
ATOM   1723  N  N   . ASP A 1 238 ? 16.245  35.073  41.080  1.00 48.06  ? 238 ASP A N   1 
ATOM   1724  C  CA  . ASP A 1 238 ? 15.883  34.870  39.690  1.00 45.14  ? 238 ASP A CA  1 
ATOM   1725  C  C   . ASP A 1 238 ? 14.447  34.356  39.603  1.00 36.33  ? 238 ASP A C   1 
ATOM   1726  O  O   . ASP A 1 238 ? 14.004  33.538  40.392  1.00 33.25  ? 238 ASP A O   1 
ATOM   1727  C  CB  . ASP A 1 238 ? 16.869  33.931  39.027  1.00 59.11  ? 238 ASP A CB  1 
ATOM   1728  C  CG  . ASP A 1 238 ? 18.275  34.484  38.985  1.00 63.23  ? 238 ASP A CG  1 
ATOM   1729  O  OD1 . ASP A 1 238 ? 18.440  35.638  38.491  1.00 67.94  ? 238 ASP A OD1 1 
ATOM   1730  O  OD2 . ASP A 1 238 ? 19.136  33.762  39.514  1.00 74.40  ? 238 ASP A OD2 1 
ATOM   1731  N  N   . LEU A 1 239 ? 13.681  34.920  38.661  1.00 33.73  ? 239 LEU A N   1 
ATOM   1732  C  CA  . LEU A 1 239 ? 12.370  34.446  38.313  1.00 30.31  ? 239 LEU A CA  1 
ATOM   1733  C  C   . LEU A 1 239 ? 12.561  33.511  37.139  1.00 31.56  ? 239 LEU A C   1 
ATOM   1734  O  O   . LEU A 1 239 ? 13.127  33.916  36.149  1.00 43.74  ? 239 LEU A O   1 
ATOM   1735  C  CB  . LEU A 1 239 ? 11.506  35.646  37.935  1.00 45.21  ? 239 LEU A CB  1 
ATOM   1736  C  CG  . LEU A 1 239 ? 11.145  36.652  39.060  1.00 45.76  ? 239 LEU A CG  1 
ATOM   1737  C  CD1 . LEU A 1 239 ? 10.276  37.743  38.365  1.00 44.68  ? 239 LEU A CD1 1 
ATOM   1738  C  CD2 . LEU A 1 239 ? 10.504  36.019  40.340  1.00 35.15  ? 239 LEU A CD2 1 
ATOM   1739  N  N   . GLU A 1 240 ? 12.135  32.253  37.271  1.00 31.27  ? 240 GLU A N   1 
ATOM   1740  C  CA  . GLU A 1 240 ? 12.483  31.199  36.342  1.00 25.79  ? 240 GLU A CA  1 
ATOM   1741  C  C   . GLU A 1 240 ? 11.221  30.538  35.838  1.00 21.23  ? 240 GLU A C   1 
ATOM   1742  O  O   . GLU A 1 240 ? 10.198  30.513  36.503  1.00 22.48  ? 240 GLU A O   1 
ATOM   1743  C  CB  . GLU A 1 240 ? 13.320  30.208  37.139  1.00 27.72  ? 240 GLU A CB  1 
ATOM   1744  C  CG  . GLU A 1 240 ? 14.629  30.769  37.734  1.00 30.23  ? 240 GLU A CG  1 
ATOM   1745  C  CD  . GLU A 1 240 ? 15.484  29.629  38.283  1.00 37.68  ? 240 GLU A CD  1 
ATOM   1746  O  OE1 . GLU A 1 240 ? 15.189  28.891  39.291  1.00 47.62  ? 240 GLU A OE1 1 
ATOM   1747  O  OE2 . GLU A 1 240 ? 16.456  29.381  37.568  1.00 45.42  ? 240 GLU A OE2 1 
ATOM   1748  N  N   . ILE A 1 241 ? 11.296  30.022  34.644  1.00 20.29  ? 241 ILE A N   1 
ATOM   1749  C  CA  . ILE A 1 241 ? 10.298  29.127  34.081  1.00 20.44  ? 241 ILE A CA  1 
ATOM   1750  C  C   . ILE A 1 241 ? 10.944  27.844  33.581  1.00 20.73  ? 241 ILE A C   1 
ATOM   1751  O  O   . ILE A 1 241 ? 12.145  27.752  33.429  1.00 23.33  ? 241 ILE A O   1 
ATOM   1752  C  CB  . ILE A 1 241 ? 9.494   29.788  32.953  1.00 20.50  ? 241 ILE A CB  1 
ATOM   1753  C  CG1 . ILE A 1 241 ? 10.271  29.996  31.710  1.00 22.78  ? 241 ILE A CG1 1 
ATOM   1754  C  CG2 . ILE A 1 241 ? 8.900   31.103  33.439  1.00 22.81  ? 241 ILE A CG2 1 
ATOM   1755  C  CD1 . ILE A 1 241 ? 9.412   30.543  30.581  1.00 26.44  ? 241 ILE A CD1 1 
ATOM   1756  N  N   . LEU A 1 242 ? 10.108  26.853  33.302  1.00 19.90  ? 242 LEU A N   1 
ATOM   1757  C  CA  . LEU A 1 242 ? 10.568  25.632  32.710  1.00 20.18  ? 242 LEU A CA  1 
ATOM   1758  C  C   . LEU A 1 242 ? 10.083  25.559  31.284  1.00 19.05  ? 242 LEU A C   1 
ATOM   1759  O  O   . LEU A 1 242 ? 8.887   25.528  31.072  1.00 20.99  ? 242 LEU A O   1 
ATOM   1760  C  CB  . LEU A 1 242 ? 10.024  24.467  33.507  1.00 21.09  ? 242 LEU A CB  1 
ATOM   1761  C  CG  . LEU A 1 242 ? 10.574  23.114  33.019  1.00 23.52  ? 242 LEU A CG  1 
ATOM   1762  C  CD1 . LEU A 1 242 ? 12.066  22.967  33.251  1.00 23.89  ? 242 LEU A CD1 1 
ATOM   1763  C  CD2 . LEU A 1 242 ? 9.870   22.042  33.797  1.00 24.85  ? 242 LEU A CD2 1 
ATOM   1764  N  N   . ARG A 1 243 ? 10.987  25.433  30.342  1.00 17.48  ? 243 ARG A N   1 
ATOM   1765  C  CA  . ARG A 1 243 ? 10.670  25.413  28.944  1.00 18.46  ? 243 ARG A CA  1 
ATOM   1766  C  C   . ARG A 1 243 ? 10.935  24.022  28.378  1.00 19.36  ? 243 ARG A C   1 
ATOM   1767  O  O   . ARG A 1 243 ? 11.808  23.336  28.865  1.00 18.49  ? 243 ARG A O   1 
ATOM   1768  C  CB  . ARG A 1 243 ? 11.504  26.395  28.126  1.00 20.13  ? 243 ARG A CB  1 
ATOM   1769  C  CG  . ARG A 1 243 ? 11.289  27.824  28.554  1.00 19.83  ? 243 ARG A CG  1 
ATOM   1770  C  CD  . ARG A 1 243 ? 12.297  28.726  27.928  1.00 22.97  ? 243 ARG A CD  1 
ATOM   1771  N  NE  . ARG A 1 243 ? 13.530  28.592  28.688  1.00 27.36  ? 243 ARG A NE  1 
ATOM   1772  C  CZ  . ARG A 1 243 ? 14.694  28.168  28.157  1.00 29.11  ? 243 ARG A CZ  1 
ATOM   1773  N  NH1 . ARG A 1 243 ? 14.800  28.064  26.841  1.00 25.96  ? 243 ARG A NH1 1 
ATOM   1774  N  NH2 . ARG A 1 243 ? 15.750  27.899  28.943  1.00 30.90  ? 243 ARG A NH2 1 
ATOM   1775  N  N   . ASP A 1 244 ? 10.181  23.619  27.355  1.00 20.15  ? 244 ASP A N   1 
ATOM   1776  C  CA  . ASP A 1 244 ? 10.485  22.412  26.616  1.00 23.73  ? 244 ASP A CA  1 
ATOM   1777  C  C   . ASP A 1 244 ? 10.194  22.642  25.137  1.00 20.39  ? 244 ASP A C   1 
ATOM   1778  O  O   . ASP A 1 244 ? 9.444   21.898  24.525  1.00 23.41  ? 244 ASP A O   1 
ATOM   1779  C  CB  . ASP A 1 244 ? 9.820   21.194  27.235  1.00 24.95  ? 244 ASP A CB  1 
ATOM   1780  C  CG  . ASP A 1 244 ? 10.521  19.880  26.892  1.00 28.12  ? 244 ASP A CG  1 
ATOM   1781  O  OD1 . ASP A 1 244 ? 11.569  19.910  26.248  1.00 32.00  ? 244 ASP A OD1 1 
ATOM   1782  O  OD2 . ASP A 1 244 ? 9.998   18.850  27.247  1.00 29.56  ? 244 ASP A OD2 1 
ATOM   1783  N  N   . ASN A 1 245 ? 10.888  23.626  24.580  1.00 21.92  ? 245 ASN A N   1 
ATOM   1784  C  CA  . ASN A 1 245 ? 10.733  23.980  23.170  1.00 24.70  ? 245 ASN A CA  1 
ATOM   1785  C  C   . ASN A 1 245 ? 11.062  22.788  22.256  1.00 22.89  ? 245 ASN A C   1 
ATOM   1786  O  O   . ASN A 1 245 ? 12.025  22.060  22.508  1.00 25.54  ? 245 ASN A O   1 
ATOM   1787  C  CB  . ASN A 1 245 ? 11.653  25.137  22.779  1.00 26.28  ? 245 ASN A CB  1 
ATOM   1788  C  CG  . ASN A 1 245 ? 11.365  26.385  23.594  1.00 31.59  ? 245 ASN A CG  1 
ATOM   1789  O  OD1 . ASN A 1 245 ? 10.353  26.477  24.336  1.00 31.51  ? 245 ASN A OD1 1 
ATOM   1790  N  ND2 . ASN A 1 245 ? 12.277  27.349  23.491  1.00 34.15  ? 245 ASN A ND2 1 
ATOM   1791  N  N   . MET A 1 246 ? 10.252  22.615  21.211  1.00 19.52  ? 246 MET A N   1 
ATOM   1792  C  CA  . MET A 1 246 ? 10.459  21.580  20.213  1.00 20.86  ? 246 MET A CA  1 
ATOM   1793  C  C   . MET A 1 246 ? 10.471  22.178  18.815  1.00 22.94  ? 246 MET A C   1 
ATOM   1794  O  O   . MET A 1 246 ? 9.516   22.852  18.435  1.00 24.40  ? 246 MET A O   1 
ATOM   1795  C  CB  . MET A 1 246 ? 9.385   20.497  20.251  1.00 23.22  ? 246 MET A CB  1 
ATOM   1796  C  CG  . MET A 1 246 ? 9.398   19.760  21.530  1.00 29.09  ? 246 MET A CG  1 
ATOM   1797  S  SD  . MET A 1 246 ? 10.886  18.777  21.750  1.00 27.70  ? 246 MET A SD  1 
ATOM   1798  C  CE  . MET A 1 246 ? 10.536  17.320  20.772  1.00 27.67  ? 246 MET A CE  1 
ATOM   1799  N  N   . PRO A 1 247 ? 11.502  21.868  18.003  1.00 21.02  ? 247 PRO A N   1 
ATOM   1800  C  CA  . PRO A 1 247 ? 11.452  22.078  16.567  1.00 21.81  ? 247 PRO A CA  1 
ATOM   1801  C  C   . PRO A 1 247 ? 10.337  21.274  15.878  1.00 18.91  ? 247 PRO A C   1 
ATOM   1802  O  O   . PRO A 1 247 ? 9.961   20.165  16.301  1.00 17.26  ? 247 PRO A O   1 
ATOM   1803  C  CB  . PRO A 1 247 ? 12.796  21.554  16.069  1.00 23.55  ? 247 PRO A CB  1 
ATOM   1804  C  CG  . PRO A 1 247 ? 13.621  21.401  17.296  1.00 26.82  ? 247 PRO A CG  1 
ATOM   1805  C  CD  . PRO A 1 247 ? 12.674  21.114  18.417  1.00 24.55  ? 247 PRO A CD  1 
ATOM   1806  N  N   . PHE A 1 248 ? 9.885   21.824  14.765  1.00 16.29  ? 248 PHE A N   1 
ATOM   1807  C  CA  . PHE A 1 248 ? 8.947   21.104  13.916  1.00 17.98  ? 248 PHE A CA  1 
ATOM   1808  C  C   . PHE A 1 248 ? 9.119   21.714  12.538  1.00 17.96  ? 248 PHE A C   1 
ATOM   1809  O  O   . PHE A 1 248 ? 9.663   22.810  12.365  1.00 18.38  ? 248 PHE A O   1 
ATOM   1810  C  CB  . PHE A 1 248 ? 7.459   21.176  14.335  1.00 18.07  ? 248 PHE A CB  1 
ATOM   1811  C  CG  . PHE A 1 248 ? 6.915   22.604  14.257  1.00 18.44  ? 248 PHE A CG  1 
ATOM   1812  C  CD1 . PHE A 1 248 ? 7.141   23.570  15.270  1.00 21.49  ? 248 PHE A CD1 1 
ATOM   1813  C  CD2 . PHE A 1 248 ? 6.231   23.022  13.137  1.00 18.65  ? 248 PHE A CD2 1 
ATOM   1814  C  CE1 . PHE A 1 248 ? 6.660   24.887  15.126  1.00 19.94  ? 248 PHE A CE1 1 
ATOM   1815  C  CE2 . PHE A 1 248 ? 5.782   24.329  13.020  1.00 19.93  ? 248 PHE A CE2 1 
ATOM   1816  C  CZ  . PHE A 1 248 ? 6.000   25.268  13.982  1.00 18.47  ? 248 PHE A CZ  1 
ATOM   1817  N  N   . GLY A 1 249 ? 8.603   21.030  11.545  1.00 21.06  ? 249 GLY A N   1 
ATOM   1818  C  CA  . GLY A 1 249 ? 8.532   21.689  10.261  1.00 23.40  ? 249 GLY A CA  1 
ATOM   1819  C  C   . GLY A 1 249 ? 8.046   20.811  9.103   1.00 22.57  ? 249 GLY A C   1 
ATOM   1820  O  O   . GLY A 1 249 ? 7.778   19.604  9.225   1.00 21.00  ? 249 GLY A O   1 
ATOM   1821  N  N   . SER A 1 250 ? 8.105   21.473  7.937   1.00 23.92  ? 250 SER A N   1 
ATOM   1822  C  CA  . SER A 1 250 ? 7.808   20.822  6.693   1.00 25.28  ? 250 SER A CA  1 
ATOM   1823  C  C   . SER A 1 250 ? 8.721   21.428  5.617   1.00 28.19  ? 250 SER A C   1 
ATOM   1824  O  O   . SER A 1 250 ? 8.761   22.613  5.396   1.00 28.69  ? 250 SER A O   1 
ATOM   1825  C  CB  . SER A 1 250 ? 6.309   20.892  6.437   1.00 25.33  ? 250 SER A CB  1 
ATOM   1826  O  OG  . SER A 1 250 ? 6.026   20.937  5.034   1.00 34.80  ? 250 SER A OG  1 
ATOM   1827  N  N   . VAL A 1 251 ? 9.547   20.605  4.983   1.00 27.39  ? 251 VAL A N   1 
ATOM   1828  C  CA  . VAL A 1 251 ? 10.538  21.077  4.044   1.00 25.29  ? 251 VAL A CA  1 
ATOM   1829  C  C   . VAL A 1 251 ? 9.891   21.567  2.752   1.00 22.01  ? 251 VAL A C   1 
ATOM   1830  O  O   . VAL A 1 251 ? 10.322  22.540  2.175   1.00 21.14  ? 251 VAL A O   1 
ATOM   1831  C  CB  . VAL A 1 251 ? 11.364  19.801  3.892   1.00 33.91  ? 251 VAL A CB  1 
ATOM   1832  C  CG1 . VAL A 1 251 ? 11.865  19.596  2.512   1.00 38.19  ? 251 VAL A CG1 1 
ATOM   1833  C  CG2 . VAL A 1 251 ? 12.526  19.779  4.854   1.00 40.77  ? 251 VAL A CG2 1 
ATOM   1834  N  N   . GLY A 1 252 ? 8.803   20.932  2.355   1.00 23.47  ? 252 GLY A N   1 
ATOM   1835  C  CA  . GLY A 1 252 ? 8.096   21.271  1.140   1.00 24.73  ? 252 GLY A CA  1 
ATOM   1836  C  C   . GLY A 1 252 ? 7.504   22.681  1.207   1.00 28.74  ? 252 GLY A C   1 
ATOM   1837  O  O   . GLY A 1 252 ? 7.520   23.386  0.262   1.00 32.33  ? 252 GLY A O   1 
ATOM   1838  N  N   . ARG A 1 253 ? 6.999   23.113  2.345   1.00 27.98  ? 253 ARG A N   1 
ATOM   1839  C  CA  . ARG A 1 253 ? 6.355   24.379  2.523   1.00 26.04  ? 253 ARG A CA  1 
ATOM   1840  C  C   . ARG A 1 253 ? 7.338   25.399  3.057   1.00 27.12  ? 253 ARG A C   1 
ATOM   1841  O  O   . ARG A 1 253 ? 6.949   26.522  3.372   1.00 29.79  ? 253 ARG A O   1 
ATOM   1842  C  CB  . ARG A 1 253 ? 5.185   24.179  3.504   1.00 32.40  ? 253 ARG A CB  1 
ATOM   1843  C  CG  . ARG A 1 253 ? 4.044   23.417  2.833   1.00 42.84  ? 253 ARG A CG  1 
ATOM   1844  C  CD  . ARG A 1 253 ? 2.609   23.817  3.221   1.00 48.82  ? 253 ARG A CD  1 
ATOM   1845  N  NE  . ARG A 1 253 ? 2.631   23.754  4.683   1.00 70.75  ? 253 ARG A NE  1 
ATOM   1846  C  CZ  . ARG A 1 253 ? 2.916   22.709  5.519   1.00 75.48  ? 253 ARG A CZ  1 
ATOM   1847  N  NH1 . ARG A 1 253 ? 3.267   22.988  6.762   1.00 75.56  ? 253 ARG A NH1 1 
ATOM   1848  N  NH2 . ARG A 1 253 ? 2.904   21.416  5.168   1.00 59.45  ? 253 ARG A NH2 1 
ATOM   1849  N  N   . GLU A 1 254 ? 8.606   25.044  3.156   1.00 25.38  ? 254 GLU A N   1 
ATOM   1850  C  CA  . GLU A 1 254 ? 9.593   25.943  3.754   1.00 27.83  ? 254 GLU A CA  1 
ATOM   1851  C  C   . GLU A 1 254 ? 9.156   26.448  5.119   1.00 25.23  ? 254 GLU A C   1 
ATOM   1852  O  O   . GLU A 1 254 ? 9.421   27.596  5.420   1.00 25.56  ? 254 GLU A O   1 
ATOM   1853  C  CB  . GLU A 1 254 ? 9.925   27.163  2.913   1.00 31.45  ? 254 GLU A CB  1 
ATOM   1854  C  CG  . GLU A 1 254 ? 10.651  26.699  1.658   1.00 40.18  ? 254 GLU A CG  1 
ATOM   1855  C  CD  . GLU A 1 254 ? 10.906  27.764  0.590   1.00 47.87  ? 254 GLU A CD  1 
ATOM   1856  O  OE1 . GLU A 1 254 ? 11.318  28.912  1.020   1.00 37.33  ? 254 GLU A OE1 1 
ATOM   1857  O  OE2 . GLU A 1 254 ? 10.722  27.419  -0.632  1.00 36.46  ? 254 GLU A OE2 1 
ATOM   1858  N  N   . GLU A 1 255 ? 8.635   25.568  5.956   1.00 21.23  ? 255 GLU A N   1 
ATOM   1859  C  CA  . GLU A 1 255 ? 8.180   25.904  7.286   1.00 22.63  ? 255 GLU A CA  1 
ATOM   1860  C  C   . GLU A 1 255 ? 9.139   25.301  8.300   1.00 23.07  ? 255 GLU A C   1 
ATOM   1861  O  O   . GLU A 1 255 ? 9.340   24.067  8.383   1.00 22.35  ? 255 GLU A O   1 
ATOM   1862  C  CB  . GLU A 1 255 ? 6.798   25.296  7.280   1.00 28.79  ? 255 GLU A CB  1 
ATOM   1863  C  CG  . GLU A 1 255 ? 6.060   25.506  8.584   1.00 46.25  ? 255 GLU A CG  1 
ATOM   1864  C  CD  . GLU A 1 255 ? 4.602   25.109  8.446   1.00 50.93  ? 255 GLU A CD  1 
ATOM   1865  O  OE1 . GLU A 1 255 ? 4.009   25.410  7.368   1.00 48.79  ? 255 GLU A OE1 1 
ATOM   1866  O  OE2 . GLU A 1 255 ? 4.126   24.487  9.420   1.00 49.10  ? 255 GLU A OE2 1 
ATOM   1867  N  N   . PHE A 1 256 ? 9.825   26.216  9.013   1.00 22.10  ? 256 PHE A N   1 
ATOM   1868  C  CA  . PHE A 1 256 ? 10.763  25.817  10.044  1.00 20.97  ? 256 PHE A CA  1 
ATOM   1869  C  C   . PHE A 1 256 ? 10.360  26.520  11.320  1.00 22.66  ? 256 PHE A C   1 
ATOM   1870  O  O   . PHE A 1 256 ? 10.271  27.736  11.330  1.00 19.57  ? 256 PHE A O   1 
ATOM   1871  C  CB  . PHE A 1 256 ? 12.159  26.203  9.587   1.00 21.85  ? 256 PHE A CB  1 
ATOM   1872  C  CG  . PHE A 1 256 ? 12.564  25.527  8.293   1.00 28.04  ? 256 PHE A CG  1 
ATOM   1873  C  CD1 . PHE A 1 256 ? 12.943  24.190  8.246   1.00 34.20  ? 256 PHE A CD1 1 
ATOM   1874  C  CD2 . PHE A 1 256 ? 12.547  26.253  7.116   1.00 29.83  ? 256 PHE A CD2 1 
ATOM   1875  C  CE1 . PHE A 1 256 ? 13.189  23.579  7.033   1.00 40.63  ? 256 PHE A CE1 1 
ATOM   1876  C  CE2 . PHE A 1 256 ? 12.872  25.660  5.910   1.00 31.46  ? 256 PHE A CE2 1 
ATOM   1877  C  CZ  . PHE A 1 256 ? 13.190  24.323  5.869   1.00 35.53  ? 256 PHE A CZ  1 
ATOM   1878  N  N   . GLY A 1 257 ? 10.083  25.751  12.375  1.00 24.73  ? 257 GLY A N   1 
ATOM   1879  C  CA  . GLY A 1 257 ? 9.430   26.293  13.542  1.00 22.53  ? 257 GLY A CA  1 
ATOM   1880  C  C   . GLY A 1 257 ? 10.075  25.883  14.867  1.00 20.91  ? 257 GLY A C   1 
ATOM   1881  O  O   . GLY A 1 257 ? 10.814  24.939  14.942  1.00 17.63  ? 257 GLY A O   1 
ATOM   1882  N  N   . THR A 1 258 ? 9.716   26.647  15.905  1.00 25.69  ? 258 THR A N   1 
ATOM   1883  C  CA  . THR A 1 258 ? 9.952   26.296  17.302  1.00 24.21  ? 258 THR A CA  1 
ATOM   1884  C  C   . THR A 1 258 ? 8.586   26.339  17.964  1.00 18.16  ? 258 THR A C   1 
ATOM   1885  O  O   . THR A 1 258 ? 7.896   27.330  17.872  1.00 19.76  ? 258 THR A O   1 
ATOM   1886  C  CB  . THR A 1 258 ? 10.962  27.275  17.935  1.00 25.84  ? 258 THR A CB  1 
ATOM   1887  O  OG1 . THR A 1 258 ? 12.286  27.159  17.384  1.00 21.95  ? 258 THR A OG1 1 
ATOM   1888  C  CG2 . THR A 1 258 ? 10.971  27.137  19.458  1.00 22.81  ? 258 THR A CG2 1 
ATOM   1889  N  N   . TYR A 1 259 ? 8.179   25.267  18.607  1.00 18.25  ? 259 TYR A N   1 
ATOM   1890  C  CA  . TYR A 1 259 ? 6.973   25.280  19.427  1.00 19.07  ? 259 TYR A CA  1 
ATOM   1891  C  C   . TYR A 1 259 ? 7.407   25.588  20.856  1.00 18.46  ? 259 TYR A C   1 
ATOM   1892  O  O   . TYR A 1 259 ? 8.072   24.827  21.498  1.00 19.37  ? 259 TYR A O   1 
ATOM   1893  C  CB  . TYR A 1 259 ? 6.142   23.993  19.328  1.00 21.54  ? 259 TYR A CB  1 
ATOM   1894  C  CG  . TYR A 1 259 ? 4.694   24.129  19.744  1.00 23.27  ? 259 TYR A CG  1 
ATOM   1895  C  CD1 . TYR A 1 259 ? 4.348   24.051  21.080  1.00 26.55  ? 259 TYR A CD1 1 
ATOM   1896  C  CD2 . TYR A 1 259 ? 3.661   24.328  18.826  1.00 25.11  ? 259 TYR A CD2 1 
ATOM   1897  C  CE1 . TYR A 1 259 ? 3.036   24.210  21.497  1.00 24.18  ? 259 TYR A CE1 1 
ATOM   1898  C  CE2 . TYR A 1 259 ? 2.346   24.449  19.226  1.00 20.60  ? 259 TYR A CE2 1 
ATOM   1899  C  CZ  . TYR A 1 259 ? 2.043   24.389  20.556  1.00 25.29  ? 259 TYR A CZ  1 
ATOM   1900  O  OH  . TYR A 1 259 ? 0.782   24.543  20.986  1.00 27.93  ? 259 TYR A OH  1 
ATOM   1901  N  N   . PHE A 1 260 ? 7.038   26.758  21.341  1.00 17.62  ? 260 PHE A N   1 
ATOM   1902  C  CA  . PHE A 1 260 ? 7.416   27.205  22.650  1.00 19.68  ? 260 PHE A CA  1 
ATOM   1903  C  C   . PHE A 1 260 ? 6.360   26.733  23.647  1.00 22.24  ? 260 PHE A C   1 
ATOM   1904  O  O   . PHE A 1 260 ? 5.160   26.924  23.406  1.00 19.77  ? 260 PHE A O   1 
ATOM   1905  C  CB  . PHE A 1 260 ? 7.511   28.721  22.685  1.00 19.84  ? 260 PHE A CB  1 
ATOM   1906  C  CG  . PHE A 1 260 ? 7.631   29.242  24.097  1.00 22.95  ? 260 PHE A CG  1 
ATOM   1907  C  CD1 . PHE A 1 260 ? 8.850   29.255  24.724  1.00 27.63  ? 260 PHE A CD1 1 
ATOM   1908  C  CD2 . PHE A 1 260 ? 6.542   29.690  24.787  1.00 25.15  ? 260 PHE A CD2 1 
ATOM   1909  C  CE1 . PHE A 1 260 ? 8.980   29.731  26.010  1.00 27.38  ? 260 PHE A CE1 1 
ATOM   1910  C  CE2 . PHE A 1 260 ? 6.682   30.124  26.075  1.00 27.17  ? 260 PHE A CE2 1 
ATOM   1911  C  CZ  . PHE A 1 260 ? 7.899   30.159  26.681  1.00 22.66  ? 260 PHE A CZ  1 
ATOM   1912  N  N   . ILE A 1 261 ? 6.826   26.135  24.759  1.00 19.69  ? 261 ILE A N   1 
ATOM   1913  C  CA  . ILE A 1 261 ? 5.956   25.881  25.895  1.00 21.46  ? 261 ILE A CA  1 
ATOM   1914  C  C   . ILE A 1 261 ? 6.751   26.230  27.151  1.00 20.44  ? 261 ILE A C   1 
ATOM   1915  O  O   . ILE A 1 261 ? 7.880   25.802  27.269  1.00 19.53  ? 261 ILE A O   1 
ATOM   1916  C  CB  . ILE A 1 261 ? 5.338   24.466  25.909  1.00 19.65  ? 261 ILE A CB  1 
ATOM   1917  C  CG1 . ILE A 1 261 ? 4.363   24.321  27.018  1.00 21.26  ? 261 ILE A CG1 1 
ATOM   1918  C  CG2 . ILE A 1 261 ? 6.399   23.386  26.036  1.00 21.06  ? 261 ILE A CG2 1 
ATOM   1919  C  CD1 . ILE A 1 261 ? 3.467   23.083  26.848  1.00 23.12  ? 261 ILE A CD1 1 
ATOM   1920  N  N   . GLY A 1 262 ? 6.189   27.114  27.982  1.00 21.04  ? 262 GLY A N   1 
ATOM   1921  C  CA  . GLY A 1 262 ? 6.794   27.550  29.222  1.00 19.67  ? 262 GLY A CA  1 
ATOM   1922  C  C   . GLY A 1 262 ? 5.837   27.293  30.395  1.00 20.26  ? 262 GLY A C   1 
ATOM   1923  O  O   . GLY A 1 262 ? 4.727   27.818  30.390  1.00 20.69  ? 262 GLY A O   1 
ATOM   1924  N  N   . TYR A 1 263 ? 6.308   26.535  31.409  1.00 18.55  ? 263 TYR A N   1 
ATOM   1925  C  CA  . TYR A 1 263 ? 5.571   26.322  32.615  1.00 18.84  ? 263 TYR A CA  1 
ATOM   1926  C  C   . TYR A 1 263 ? 6.078   27.220  33.746  1.00 21.61  ? 263 TYR A C   1 
ATOM   1927  O  O   . TYR A 1 263 ? 7.271   27.336  33.885  1.00 19.19  ? 263 TYR A O   1 
ATOM   1928  C  CB  . TYR A 1 263 ? 5.699   24.870  32.988  1.00 19.28  ? 263 TYR A CB  1 
ATOM   1929  C  CG  . TYR A 1 263 ? 4.963   23.868  32.141  1.00 19.54  ? 263 TYR A CG  1 
ATOM   1930  C  CD1 . TYR A 1 263 ? 3.681   23.475  32.450  1.00 20.65  ? 263 TYR A CD1 1 
ATOM   1931  C  CD2 . TYR A 1 263 ? 5.605   23.237  31.101  1.00 20.20  ? 263 TYR A CD2 1 
ATOM   1932  C  CE1 . TYR A 1 263 ? 3.028   22.514  31.676  1.00 22.98  ? 263 TYR A CE1 1 
ATOM   1933  C  CE2 . TYR A 1 263 ? 4.983   22.267  30.345  1.00 19.36  ? 263 TYR A CE2 1 
ATOM   1934  C  CZ  . TYR A 1 263 ? 3.693   21.872  30.635  1.00 19.86  ? 263 TYR A CZ  1 
ATOM   1935  O  OH  . TYR A 1 263 ? 3.074   20.948  29.867  1.00 18.68  ? 263 TYR A OH  1 
ATOM   1936  N  N   . ALA A 1 264 ? 5.157   27.742  34.597  1.00 22.67  ? 264 ALA A N   1 
ATOM   1937  C  CA  . ALA A 1 264 ? 5.500   28.553  35.751  1.00 20.71  ? 264 ALA A CA  1 
ATOM   1938  C  C   . ALA A 1 264 ? 4.385   28.484  36.771  1.00 23.87  ? 264 ALA A C   1 
ATOM   1939  O  O   . ALA A 1 264 ? 3.238   28.208  36.400  1.00 20.27  ? 264 ALA A O   1 
ATOM   1940  C  CB  . ALA A 1 264 ? 5.680   29.995  35.352  1.00 22.13  ? 264 ALA A CB  1 
ATOM   1941  N  N   . ARG A 1 265 ? 4.743   28.777  38.044  1.00 25.56  ? 265 ARG A N   1 
ATOM   1942  C  CA  . ARG A 1 265 ? 3.817   28.695  39.193  1.00 25.05  ? 265 ARG A CA  1 
ATOM   1943  C  C   . ARG A 1 265 ? 2.752   29.804  39.093  1.00 24.13  ? 265 ARG A C   1 
ATOM   1944  O  O   . ARG A 1 265 ? 1.692   29.686  39.676  1.00 22.08  ? 265 ARG A O   1 
ATOM   1945  C  CB  . ARG A 1 265 ? 4.464   28.670  40.596  1.00 25.07  ? 265 ARG A CB  1 
ATOM   1946  C  CG  . ARG A 1 265 ? 5.087   30.039  40.946  1.00 36.45  ? 265 ARG A CG  1 
ATOM   1947  C  CD  . ARG A 1 265 ? 5.832   30.468  42.233  1.00 47.42  ? 265 ARG A CD  1 
ATOM   1948  N  NE  . ARG A 1 265 ? 5.068   30.052  43.406  1.00 67.13  ? 265 ARG A NE  1 
ATOM   1949  C  CZ  . ARG A 1 265 ? 5.345   28.958  44.171  1.00 79.30  ? 265 ARG A CZ  1 
ATOM   1950  N  NH1 . ARG A 1 265 ? 6.559   28.468  44.249  1.00 89.53  ? 265 ARG A NH1 1 
ATOM   1951  N  NH2 . ARG A 1 265 ? 4.475   28.411  44.998  1.00 69.55  ? 265 ARG A NH2 1 
ATOM   1952  N  N   . THR A 1 266 ? 3.034   30.882  38.365  1.00 22.22  ? 266 THR A N   1 
ATOM   1953  C  CA  . THR A 1 266 ? 2.050   31.930  38.132  1.00 24.87  ? 266 THR A CA  1 
ATOM   1954  C  C   . THR A 1 266 ? 2.314   32.491  36.734  1.00 26.61  ? 266 THR A C   1 
ATOM   1955  O  O   . THR A 1 266 ? 3.469   32.606  36.309  1.00 23.04  ? 266 THR A O   1 
ATOM   1956  C  CB  . THR A 1 266 ? 2.212   33.038  39.187  1.00 23.60  ? 266 THR A CB  1 
ATOM   1957  O  OG1 . THR A 1 266 ? 1.520   34.156  38.685  1.00 25.36  ? 266 THR A OG1 1 
ATOM   1958  C  CG2 . THR A 1 266 ? 3.623   33.578  39.285  1.00 21.99  ? 266 THR A CG2 1 
ATOM   1959  N  N   . PRO A 1 267 ? 1.285   32.908  35.977  1.00 24.67  ? 267 PRO A N   1 
ATOM   1960  C  CA  . PRO A 1 267 ? 1.524   33.439  34.645  1.00 25.51  ? 267 PRO A CA  1 
ATOM   1961  C  C   . PRO A 1 267 ? 2.227   34.780  34.635  1.00 24.97  ? 267 PRO A C   1 
ATOM   1962  O  O   . PRO A 1 267 ? 2.777   35.119  33.618  1.00 24.71  ? 267 PRO A O   1 
ATOM   1963  C  CB  . PRO A 1 267 ? 0.174   33.488  33.996  1.00 26.30  ? 267 PRO A CB  1 
ATOM   1964  C  CG  . PRO A 1 267 ? -0.812  33.416  35.102  1.00 27.87  ? 267 PRO A CG  1 
ATOM   1965  C  CD  . PRO A 1 267 ? -0.126  32.800  36.297  1.00 25.61  ? 267 PRO A CD  1 
ATOM   1966  N  N   . GLU A 1 268 ? 2.344   35.444  35.793  1.00 26.44  ? 268 GLU A N   1 
ATOM   1967  C  CA  . GLU A 1 268 ? 3.008   36.743  35.905  1.00 29.29  ? 268 GLU A CA  1 
ATOM   1968  C  C   . GLU A 1 268 ? 4.462   36.685  35.450  1.00 24.34  ? 268 GLU A C   1 
ATOM   1969  O  O   . GLU A 1 268 ? 4.959   37.586  34.775  1.00 21.01  ? 268 GLU A O   1 
ATOM   1970  C  CB  . GLU A 1 268 ? 2.830   37.293  37.318  1.00 34.22  ? 268 GLU A CB  1 
ATOM   1971  C  CG  . GLU A 1 268 ? 3.628   38.568  37.501  1.00 44.08  ? 268 GLU A CG  1 
ATOM   1972  C  CD  . GLU A 1 268 ? 2.730   39.562  38.181  1.00 52.55  ? 268 GLU A CD  1 
ATOM   1973  O  OE1 . GLU A 1 268 ? 2.540   39.462  39.404  1.00 61.42  ? 268 GLU A OE1 1 
ATOM   1974  O  OE2 . GLU A 1 268 ? 2.118   40.335  37.425  1.00 62.43  ? 268 GLU A OE2 1 
ATOM   1975  N  N   . VAL A 1 269 ? 5.130   35.575  35.776  1.00 24.56  ? 269 VAL A N   1 
ATOM   1976  C  CA  . VAL A 1 269 ? 6.525   35.393  35.413  1.00 25.86  ? 269 VAL A CA  1 
ATOM   1977  C  C   . VAL A 1 269 ? 6.680   35.334  33.890  1.00 21.90  ? 269 VAL A C   1 
ATOM   1978  O  O   . VAL A 1 269 ? 7.415   36.125  33.302  1.00 19.04  ? 269 VAL A O   1 
ATOM   1979  C  CB  . VAL A 1 269 ? 7.146   34.147  36.080  1.00 29.35  ? 269 VAL A CB  1 
ATOM   1980  C  CG1 . VAL A 1 269 ? 8.582   33.943  35.608  1.00 36.18  ? 269 VAL A CG1 1 
ATOM   1981  C  CG2 . VAL A 1 269 ? 7.157   34.316  37.597  1.00 28.26  ? 269 VAL A CG2 1 
ATOM   1982  N  N   . THR A 1 270 ? 5.962   34.398  33.284  1.00 19.94  ? 270 THR A N   1 
ATOM   1983  C  CA  . THR A 1 270 ? 5.990   34.206  31.834  1.00 21.19  ? 270 THR A CA  1 
ATOM   1984  C  C   . THR A 1 270 ? 5.564   35.459  31.099  1.00 21.78  ? 270 THR A C   1 
ATOM   1985  O  O   . THR A 1 270 ? 6.171   35.820  30.100  1.00 23.12  ? 270 THR A O   1 
ATOM   1986  C  CB  . THR A 1 270 ? 5.108   33.027  31.448  1.00 21.66  ? 270 THR A CB  1 
ATOM   1987  O  OG1 . THR A 1 270 ? 5.434   31.855  32.196  1.00 26.31  ? 270 THR A OG1 1 
ATOM   1988  C  CG2 . THR A 1 270 ? 5.388   32.603  30.040  1.00 22.73  ? 270 THR A CG2 1 
ATOM   1989  N  N   . GLU A 1 271 ? 4.514   36.135  31.603  1.00 25.00  ? 271 GLU A N   1 
ATOM   1990  C  CA  . GLU A 1 271 ? 3.975   37.321  30.969  1.00 22.32  ? 271 GLU A CA  1 
ATOM   1991  C  C   . GLU A 1 271 ? 4.961   38.468  31.042  1.00 19.48  ? 271 GLU A C   1 
ATOM   1992  O  O   . GLU A 1 271 ? 4.988   39.274  30.149  1.00 19.26  ? 271 GLU A O   1 
ATOM   1993  C  CB  . GLU A 1 271 ? 2.638   37.644  31.593  1.00 24.12  ? 271 GLU A CB  1 
ATOM   1994  C  CG  . GLU A 1 271 ? 1.560   36.719  31.068  1.00 30.53  ? 271 GLU A CG  1 
ATOM   1995  C  CD  . GLU A 1 271 ? 0.153   36.854  31.649  1.00 33.66  ? 271 GLU A CD  1 
ATOM   1996  O  OE1 . GLU A 1 271 ? -0.094  37.820  32.366  1.00 35.31  ? 271 GLU A OE1 1 
ATOM   1997  O  OE2 . GLU A 1 271 ? -0.714  36.035  31.270  1.00 31.06  ? 271 GLU A OE2 1 
ATOM   1998  N  N   . THR A 1 272 ? 5.776   38.529  32.092  1.00 21.90  ? 272 THR A N   1 
ATOM   1999  C  CA  . THR A 1 272 ? 6.733   39.620  32.199  1.00 23.87  ? 272 THR A CA  1 
ATOM   2000  C  C   . THR A 1 272 ? 7.795   39.465  31.119  1.00 23.52  ? 272 THR A C   1 
ATOM   2001  O  O   . THR A 1 272 ? 8.180   40.432  30.447  1.00 25.20  ? 272 THR A O   1 
ATOM   2002  C  CB  . THR A 1 272 ? 7.359   39.627  33.598  1.00 24.88  ? 272 THR A CB  1 
ATOM   2003  O  OG1 . THR A 1 272 ? 6.304   39.917  34.486  1.00 21.89  ? 272 THR A OG1 1 
ATOM   2004  C  CG2 . THR A 1 272 ? 8.442   40.676  33.776  1.00 22.47  ? 272 THR A CG2 1 
ATOM   2005  N  N   . MET A 1 273 ? 8.268   38.227  30.969  1.00 22.56  ? 273 MET A N   1 
ATOM   2006  C  CA  . MET A 1 273 ? 9.257   37.902  29.962  1.00 22.61  ? 273 MET A CA  1 
ATOM   2007  C  C   . MET A 1 273 ? 8.702   38.267  28.584  1.00 23.14  ? 273 MET A C   1 
ATOM   2008  O  O   . MET A 1 273 ? 9.382   38.868  27.735  1.00 23.08  ? 273 MET A O   1 
ATOM   2009  C  CB  . MET A 1 273 ? 9.579   36.410  30.042  1.00 23.12  ? 273 MET A CB  1 
ATOM   2010  C  CG  . MET A 1 273 ? 10.444  36.014  31.212  1.00 25.33  ? 273 MET A CG  1 
ATOM   2011  S  SD  . MET A 1 273 ? 10.569  34.208  31.341  1.00 30.21  ? 273 MET A SD  1 
ATOM   2012  C  CE  . MET A 1 273 ? 11.583  34.051  32.816  1.00 34.31  ? 273 MET A CE  1 
ATOM   2013  N  N   . LEU A 1 274 ? 7.455   37.879  28.339  1.00 22.73  ? 274 LEU A N   1 
ATOM   2014  C  CA  . LEU A 1 274 ? 6.844   38.182  27.059  1.00 23.89  ? 274 LEU A CA  1 
ATOM   2015  C  C   . LEU A 1 274 ? 6.764   39.688  26.791  1.00 26.81  ? 274 LEU A C   1 
ATOM   2016  O  O   . LEU A 1 274 ? 6.952   40.122  25.654  1.00 26.72  ? 274 LEU A O   1 
ATOM   2017  C  CB  . LEU A 1 274 ? 5.457   37.553  27.024  1.00 24.56  ? 274 LEU A CB  1 
ATOM   2018  C  CG  . LEU A 1 274 ? 5.390   36.067  26.670  1.00 23.26  ? 274 LEU A CG  1 
ATOM   2019  C  CD1 . LEU A 1 274 ? 4.000   35.452  26.835  1.00 23.24  ? 274 LEU A CD1 1 
ATOM   2020  C  CD2 . LEU A 1 274 ? 5.792   35.930  25.223  1.00 24.17  ? 274 LEU A CD2 1 
ATOM   2021  N  N   . GLU A 1 275 ? 6.399   40.486  27.796  1.00 27.31  ? 275 GLU A N   1 
ATOM   2022  C  CA  . GLU A 1 275 ? 6.276   41.923  27.628  1.00 28.82  ? 275 GLU A CA  1 
ATOM   2023  C  C   . GLU A 1 275 ? 7.614   42.504  27.271  1.00 25.31  ? 275 GLU A C   1 
ATOM   2024  O  O   . GLU A 1 275 ? 7.658   43.341  26.392  1.00 22.83  ? 275 GLU A O   1 
ATOM   2025  C  CB  . GLU A 1 275 ? 5.855   42.689  28.877  1.00 37.70  ? 275 GLU A CB  1 
ATOM   2026  C  CG  . GLU A 1 275 ? 4.354   42.596  29.092  1.00 45.13  ? 275 GLU A CG  1 
ATOM   2027  C  CD  . GLU A 1 275 ? 3.946   43.236  30.383  1.00 52.90  ? 275 GLU A CD  1 
ATOM   2028  O  OE1 . GLU A 1 275 ? 4.677   44.183  30.798  1.00 59.71  ? 275 GLU A OE1 1 
ATOM   2029  O  OE2 . GLU A 1 275 ? 2.929   42.750  30.917  1.00 42.78  ? 275 GLU A OE2 1 
ATOM   2030  N  N   . ARG A 1 276 ? 8.666   42.036  27.959  1.00 27.21  ? 276 ARG A N   1 
ATOM   2031  C  CA  . ARG A 1 276 ? 10.001  42.533  27.672  1.00 29.88  ? 276 ARG A CA  1 
ATOM   2032  C  C   . ARG A 1 276 ? 10.426  42.173  26.257  1.00 30.34  ? 276 ARG A C   1 
ATOM   2033  O  O   . ARG A 1 276 ? 11.113  42.986  25.604  1.00 29.11  ? 276 ARG A O   1 
ATOM   2034  C  CB  . ARG A 1 276 ? 11.044  42.011  28.659  1.00 29.04  ? 276 ARG A CB  1 
ATOM   2035  C  CG  . ARG A 1 276 ? 10.843  42.710  29.996  1.00 32.73  ? 276 ARG A CG  1 
ATOM   2036  C  CD  . ARG A 1 276 ? 11.202  41.971  31.227  1.00 34.88  ? 276 ARG A CD  1 
ATOM   2037  N  NE  . ARG A 1 276 ? 12.631  41.666  31.142  1.00 43.39  ? 276 ARG A NE  1 
ATOM   2038  C  CZ  . ARG A 1 276 ? 13.628  42.437  31.495  1.00 40.97  ? 276 ARG A CZ  1 
ATOM   2039  N  NH1 . ARG A 1 276 ? 13.374  43.608  32.000  1.00 48.17  ? 276 ARG A NH1 1 
ATOM   2040  N  NH2 . ARG A 1 276 ? 14.858  42.044  31.325  1.00 36.00  ? 276 ARG A NH2 1 
ATOM   2041  N  N   . MET A 1 277 ? 10.005  40.987  25.787  1.00 23.72  ? 277 MET A N   1 
ATOM   2042  C  CA  . MET A 1 277 ? 10.416  40.572  24.470  1.00 25.71  ? 277 MET A CA  1 
ATOM   2043  C  C   . MET A 1 277 ? 9.678   41.410  23.438  1.00 22.76  ? 277 MET A C   1 
ATOM   2044  O  O   . MET A 1 277 ? 10.278  41.864  22.474  1.00 27.03  ? 277 MET A O   1 
ATOM   2045  C  CB  . MET A 1 277 ? 10.141  39.085  24.229  1.00 25.99  ? 277 MET A CB  1 
ATOM   2046  C  CG  . MET A 1 277 ? 11.045  38.106  24.998  1.00 24.30  ? 277 MET A CG  1 
ATOM   2047  S  SD  . MET A 1 277 ? 10.411  36.415  24.801  1.00 24.99  ? 277 MET A SD  1 
ATOM   2048  C  CE  . MET A 1 277 ? 10.671  36.223  23.037  1.00 27.36  ? 277 MET A CE  1 
ATOM   2049  N  N   . PHE A 1 278 ? 8.382   41.578  23.604  1.00 20.36  ? 278 PHE A N   1 
ATOM   2050  C  CA  . PHE A 1 278 ? 7.573   42.157  22.540  1.00 24.37  ? 278 PHE A CA  1 
ATOM   2051  C  C   . PHE A 1 278 ? 7.522   43.676  22.579  1.00 25.00  ? 278 PHE A C   1 
ATOM   2052  O  O   . PHE A 1 278 ? 7.367   44.314  21.521  1.00 24.00  ? 278 PHE A O   1 
ATOM   2053  C  CB  . PHE A 1 278 ? 6.168   41.565  22.578  1.00 23.15  ? 278 PHE A CB  1 
ATOM   2054  C  CG  . PHE A 1 278 ? 6.165   40.221  21.854  1.00 22.39  ? 278 PHE A CG  1 
ATOM   2055  C  CD1 . PHE A 1 278 ? 6.475   39.055  22.519  1.00 22.07  ? 278 PHE A CD1 1 
ATOM   2056  C  CD2 . PHE A 1 278 ? 5.850   40.137  20.526  1.00 23.18  ? 278 PHE A CD2 1 
ATOM   2057  C  CE1 . PHE A 1 278 ? 6.497   37.843  21.856  1.00 20.99  ? 278 PHE A CE1 1 
ATOM   2058  C  CE2 . PHE A 1 278 ? 5.844   38.905  19.890  1.00 24.27  ? 278 PHE A CE2 1 
ATOM   2059  C  CZ  . PHE A 1 278 ? 6.210   37.775  20.546  1.00 22.37  ? 278 PHE A CZ  1 
ATOM   2060  N  N   . LEU A 1 279 ? 7.504   44.205  23.806  1.00 28.98  ? 279 LEU A N   1 
ATOM   2061  C  CA  . LEU A 1 279 ? 7.258   45.627  24.002  1.00 33.50  ? 279 LEU A CA  1 
ATOM   2062  C  C   . LEU A 1 279 ? 8.535   46.338  24.372  1.00 31.32  ? 279 LEU A C   1 
ATOM   2063  O  O   . LEU A 1 279 ? 8.595   47.523  24.182  1.00 35.77  ? 279 LEU A O   1 
ATOM   2064  C  CB  . LEU A 1 279 ? 6.215   45.953  25.050  1.00 33.11  ? 279 LEU A CB  1 
ATOM   2065  C  CG  . LEU A 1 279 ? 4.885   45.225  24.884  1.00 38.35  ? 279 LEU A CG  1 
ATOM   2066  C  CD1 . LEU A 1 279 ? 3.992   45.582  26.046  1.00 43.72  ? 279 LEU A CD1 1 
ATOM   2067  C  CD2 . LEU A 1 279 ? 4.223   45.478  23.585  1.00 38.23  ? 279 LEU A CD2 1 
ATOM   2068  N  N   . GLY A 1 280 ? 9.566   45.648  24.810  1.00 32.33  ? 280 GLY A N   1 
ATOM   2069  C  CA  . GLY A 1 280 ? 10.853  46.315  24.986  1.00 36.89  ? 280 GLY A CA  1 
ATOM   2070  C  C   . GLY A 1 280 ? 11.039  46.835  26.410  1.00 36.59  ? 280 GLY A C   1 
ATOM   2071  O  O   . GLY A 1 280 ? 10.179  46.623  27.238  1.00 38.03  ? 280 GLY A O   1 
ATOM   2072  N  N   . THR A 1 281 ? 12.208  47.422  26.658  1.00 36.30  ? 281 THR A N   1 
ATOM   2073  C  CA  . THR A 1 281 ? 12.585  48.038  27.909  1.00 37.04  ? 281 THR A CA  1 
ATOM   2074  C  C   . THR A 1 281 ? 13.130  49.425  27.625  1.00 43.20  ? 281 THR A C   1 
ATOM   2075  O  O   . THR A 1 281 ? 13.143  49.865  26.478  1.00 42.77  ? 281 THR A O   1 
ATOM   2076  C  CB  . THR A 1 281 ? 13.601  47.201  28.697  1.00 35.90  ? 281 THR A CB  1 
ATOM   2077  O  OG1 . THR A 1 281 ? 14.806  47.185  27.936  1.00 47.51  ? 281 THR A OG1 1 
ATOM   2078  C  CG2 . THR A 1 281 ? 13.030  45.839  29.025  1.00 35.79  ? 281 THR A CG2 1 
ATOM   2079  N  N   . ALA A 1 282 ? 13.577  50.101  28.702  1.00 56.44  ? 282 ALA A N   1 
ATOM   2080  C  CA  . ALA A 1 282 ? 14.264  51.368  28.612  1.00 51.73  ? 282 ALA A CA  1 
ATOM   2081  C  C   . ALA A 1 282 ? 15.416  51.238  27.622  1.00 54.13  ? 282 ALA A C   1 
ATOM   2082  O  O   . ALA A 1 282 ? 15.559  52.102  26.775  1.00 50.82  ? 282 ALA A O   1 
ATOM   2083  C  CB  . ALA A 1 282 ? 14.758  51.754  29.978  1.00 49.82  ? 282 ALA A CB  1 
ATOM   2084  N  N   . SER A 1 283 ? 16.201  50.155  27.683  1.00 52.92  ? 283 SER A N   1 
ATOM   2085  C  CA  . SER A 1 283 ? 17.366  50.090  26.811  1.00 52.86  ? 283 SER A CA  1 
ATOM   2086  C  C   . SER A 1 283 ? 17.201  49.227  25.566  1.00 52.32  ? 283 SER A C   1 
ATOM   2087  O  O   . SER A 1 283 ? 18.171  49.133  24.836  1.00 50.47  ? 283 SER A O   1 
ATOM   2088  C  CB  . SER A 1 283 ? 18.602  49.675  27.537  1.00 54.34  ? 283 SER A CB  1 
ATOM   2089  O  OG  . SER A 1 283 ? 18.326  48.574  28.357  1.00 53.17  ? 283 SER A OG  1 
ATOM   2090  N  N   . ALA A 1 284 ? 16.032  48.643  25.265  1.00 47.72  ? 284 ALA A N   1 
ATOM   2091  C  CA  . ALA A 1 284 ? 15.971  47.673  24.177  1.00 39.65  ? 284 ALA A CA  1 
ATOM   2092  C  C   . ALA A 1 284 ? 14.624  47.746  23.477  1.00 41.17  ? 284 ALA A C   1 
ATOM   2093  O  O   . ALA A 1 284 ? 13.596  47.546  24.111  1.00 42.28  ? 284 ALA A O   1 
ATOM   2094  C  CB  . ALA A 1 284 ? 16.209  46.264  24.697  1.00 41.21  ? 284 ALA A CB  1 
ATOM   2095  N  N   . PRO A 1 285 ? 14.540  48.001  22.161  1.00 37.96  ? 285 PRO A N   1 
ATOM   2096  C  CA  . PRO A 1 285 ? 13.234  48.147  21.505  1.00 34.35  ? 285 PRO A CA  1 
ATOM   2097  C  C   . PRO A 1 285 ? 12.389  46.879  21.562  1.00 33.62  ? 285 PRO A C   1 
ATOM   2098  O  O   . PRO A 1 285 ? 11.187  46.997  21.648  1.00 34.52  ? 285 PRO A O   1 
ATOM   2099  C  CB  . PRO A 1 285 ? 13.484  48.633  20.074  1.00 30.79  ? 285 PRO A CB  1 
ATOM   2100  C  CG  . PRO A 1 285 ? 14.916  48.329  19.876  1.00 38.76  ? 285 PRO A CG  1 
ATOM   2101  C  CD  . PRO A 1 285 ? 15.647  48.273  21.259  1.00 42.47  ? 285 PRO A CD  1 
ATOM   2102  N  N   . HIS A 1 286 ? 13.037  45.694  21.496  1.00 30.02  ? 286 HIS A N   1 
ATOM   2103  C  CA  . HIS A 1 286 ? 12.394  44.395  21.496  1.00 28.69  ? 286 HIS A CA  1 
ATOM   2104  C  C   . HIS A 1 286 ? 13.488  43.348  21.432  1.00 29.27  ? 286 HIS A C   1 
ATOM   2105  O  O   . HIS A 1 286 ? 14.639  43.692  21.227  1.00 29.82  ? 286 HIS A O   1 
ATOM   2106  C  CB  . HIS A 1 286 ? 11.402  44.216  20.346  1.00 31.54  ? 286 HIS A CB  1 
ATOM   2107  C  CG  . HIS A 1 286 ? 11.991  44.397  18.990  1.00 36.47  ? 286 HIS A CG  1 
ATOM   2108  N  ND1 . HIS A 1 286 ? 11.847  45.552  18.242  1.00 35.59  ? 286 HIS A ND1 1 
ATOM   2109  C  CD2 . HIS A 1 286 ? 12.732  43.555  18.237  1.00 36.38  ? 286 HIS A CD2 1 
ATOM   2110  C  CE1 . HIS A 1 286 ? 12.488  45.393  17.089  1.00 33.70  ? 286 HIS A CE1 1 
ATOM   2111  N  NE2 . HIS A 1 286 ? 13.022  44.185  17.054  1.00 27.40  ? 286 HIS A NE2 1 
ATOM   2112  N  N   . ASP A 1 287 ? 13.115  42.088  21.647  1.00 28.13  ? 287 ASP A N   1 
ATOM   2113  C  CA  . ASP A 1 287 ? 14.022  40.954  21.567  1.00 28.36  ? 287 ASP A CA  1 
ATOM   2114  C  C   . ASP A 1 287 ? 14.386  40.723  20.102  1.00 24.07  ? 287 ASP A C   1 
ATOM   2115  O  O   . ASP A 1 287 ? 13.525  40.523  19.264  1.00 20.58  ? 287 ASP A O   1 
ATOM   2116  C  CB  . ASP A 1 287 ? 13.339  39.756  22.197  1.00 28.08  ? 287 ASP A CB  1 
ATOM   2117  C  CG  . ASP A 1 287 ? 14.202  38.516  22.392  1.00 31.00  ? 287 ASP A CG  1 
ATOM   2118  O  OD1 . ASP A 1 287 ? 15.193  38.360  21.654  1.00 28.61  ? 287 ASP A OD1 1 
ATOM   2119  O  OD2 . ASP A 1 287 ? 13.824  37.676  23.268  1.00 29.42  ? 287 ASP A OD2 1 
ATOM   2120  N  N   . ARG A 1 288 ? 15.680  40.757  19.810  1.00 23.88  ? 288 ARG A N   1 
ATOM   2121  C  CA  . ARG A 1 288 ? 16.141  40.530  18.458  1.00 26.49  ? 288 ARG A CA  1 
ATOM   2122  C  C   . ARG A 1 288 ? 15.714  39.178  17.877  1.00 24.80  ? 288 ARG A C   1 
ATOM   2123  O  O   . ARG A 1 288 ? 15.644  39.034  16.670  1.00 22.92  ? 288 ARG A O   1 
ATOM   2124  C  CB  . ARG A 1 288 ? 17.661  40.684  18.424  1.00 31.00  ? 288 ARG A CB  1 
ATOM   2125  C  CG  . ARG A 1 288 ? 18.102  42.135  18.509  1.00 43.24  ? 288 ARG A CG  1 
ATOM   2126  C  CD  . ARG A 1 288 ? 17.902  42.789  17.121  1.00 43.11  ? 288 ARG A CD  1 
ATOM   2127  N  NE  . ARG A 1 288 ? 18.969  42.351  16.214  1.00 42.24  ? 288 ARG A NE  1 
ATOM   2128  C  CZ  . ARG A 1 288 ? 18.916  42.190  14.899  1.00 38.69  ? 288 ARG A CZ  1 
ATOM   2129  N  NH1 . ARG A 1 288 ? 17.787  42.206  14.231  1.00 39.89  ? 288 ARG A NH1 1 
ATOM   2130  N  NH2 . ARG A 1 288 ? 20.015  41.886  14.259  1.00 34.75  ? 288 ARG A NH2 1 
ATOM   2131  N  N   . ILE A 1 289 ? 15.423  38.176  18.699  1.00 22.00  ? 289 ILE A N   1 
ATOM   2132  C  CA  . ILE A 1 289 ? 15.038  36.905  18.143  1.00 23.30  ? 289 ILE A CA  1 
ATOM   2133  C  C   . ILE A 1 289 ? 13.722  37.050  17.360  1.00 21.54  ? 289 ILE A C   1 
ATOM   2134  O  O   . ILE A 1 289 ? 13.451  36.246  16.473  1.00 19.54  ? 289 ILE A O   1 
ATOM   2135  C  CB  . ILE A 1 289 ? 14.953  35.862  19.276  1.00 26.07  ? 289 ILE A CB  1 
ATOM   2136  C  CG1 . ILE A 1 289 ? 15.164  34.467  18.778  1.00 28.71  ? 289 ILE A CG1 1 
ATOM   2137  C  CG2 . ILE A 1 289 ? 13.606  35.907  19.990  1.00 25.57  ? 289 ILE A CG2 1 
ATOM   2138  C  CD1 . ILE A 1 289 ? 15.148  33.375  19.854  1.00 29.49  ? 289 ILE A CD1 1 
ATOM   2139  N  N   . LEU A 1 290 ? 12.863  38.039  17.719  1.00 20.96  ? 290 LEU A N   1 
ATOM   2140  C  CA  . LEU A 1 290 ? 11.590  38.251  17.041  1.00 20.42  ? 290 LEU A CA  1 
ATOM   2141  C  C   . LEU A 1 290 ? 11.757  38.856  15.631  1.00 19.67  ? 290 LEU A C   1 
ATOM   2142  O  O   . LEU A 1 290 ? 10.868  38.819  14.807  1.00 17.61  ? 290 LEU A O   1 
ATOM   2143  C  CB  . LEU A 1 290 ? 10.694  39.126  17.896  1.00 19.47  ? 290 LEU A CB  1 
ATOM   2144  C  CG  . LEU A 1 290 ? 10.334  38.534  19.246  1.00 19.47  ? 290 LEU A CG  1 
ATOM   2145  C  CD1 . LEU A 1 290 ? 9.502   39.603  19.963  1.00 23.95  ? 290 LEU A CD1 1 
ATOM   2146  C  CD2 . LEU A 1 290 ? 9.557   37.296  19.128  1.00 20.05  ? 290 LEU A CD2 1 
ATOM   2147  N  N   . ASP A 1 291 ? 12.945  39.350  15.311  1.00 21.15  ? 291 ASP A N   1 
ATOM   2148  C  CA  . ASP A 1 291 ? 13.202  39.786  13.945  1.00 20.24  ? 291 ASP A CA  1 
ATOM   2149  C  C   . ASP A 1 291 ? 13.384  38.581  13.051  1.00 22.41  ? 291 ASP A C   1 
ATOM   2150  O  O   . ASP A 1 291 ? 13.484  38.774  11.855  1.00 23.38  ? 291 ASP A O   1 
ATOM   2151  C  CB  . ASP A 1 291 ? 14.391  40.727  13.844  1.00 20.17  ? 291 ASP A CB  1 
ATOM   2152  C  CG  . ASP A 1 291 ? 14.181  42.094  14.503  1.00 23.59  ? 291 ASP A CG  1 
ATOM   2153  O  OD1 . ASP A 1 291 ? 13.043  42.604  14.478  1.00 30.33  ? 291 ASP A OD1 1 
ATOM   2154  O  OD2 . ASP A 1 291 ? 15.117  42.631  15.043  1.00 22.88  ? 291 ASP A OD2 1 
ATOM   2155  N  N   . PHE A 1 292 ? 13.405  37.348  13.595  1.00 21.44  ? 292 PHE A N   1 
ATOM   2156  C  CA  . PHE A 1 292 ? 13.508  36.149  12.773  1.00 20.31  ? 292 PHE A CA  1 
ATOM   2157  C  C   . PHE A 1 292 ? 12.459  35.106  13.153  1.00 20.49  ? 292 PHE A C   1 
ATOM   2158  O  O   . PHE A 1 292 ? 12.525  33.948  12.739  1.00 21.22  ? 292 PHE A O   1 
ATOM   2159  C  CB  . PHE A 1 292 ? 14.897  35.527  12.948  1.00 21.66  ? 292 PHE A CB  1 
ATOM   2160  C  CG  . PHE A 1 292 ? 15.983  36.540  12.672  1.00 21.91  ? 292 PHE A CG  1 
ATOM   2161  C  CD1 . PHE A 1 292 ? 16.387  36.779  11.390  1.00 24.45  ? 292 PHE A CD1 1 
ATOM   2162  C  CD2 . PHE A 1 292 ? 16.524  37.318  13.680  1.00 24.50  ? 292 PHE A CD2 1 
ATOM   2163  C  CE1 . PHE A 1 292 ? 17.342  37.740  11.109  1.00 25.54  ? 292 PHE A CE1 1 
ATOM   2164  C  CE2 . PHE A 1 292 ? 17.484  38.291  13.404  1.00 25.50  ? 292 PHE A CE2 1 
ATOM   2165  C  CZ  . PHE A 1 292 ? 17.866  38.505  12.114  1.00 27.31  ? 292 PHE A CZ  1 
ATOM   2166  N  N   . SER A 1 293 ? 11.481  35.499  13.957  1.00 21.48  ? 293 SER A N   1 
ATOM   2167  C  CA  . SER A 1 293 ? 10.547  34.549  14.526  1.00 21.71  ? 293 SER A CA  1 
ATOM   2168  C  C   . SER A 1 293 ? 9.191   35.264  14.605  1.00 25.49  ? 293 SER A C   1 
ATOM   2169  O  O   . SER A 1 293 ? 9.074   36.345  15.207  1.00 28.00  ? 293 SER A O   1 
ATOM   2170  C  CB  . SER A 1 293 ? 11.001  34.045  15.905  1.00 20.82  ? 293 SER A CB  1 
ATOM   2171  O  OG  . SER A 1 293 ? 12.393  33.780  15.959  1.00 22.39  ? 293 SER A OG  1 
ATOM   2172  N  N   . THR A 1 294 ? 8.164   34.642  14.008  1.00 23.82  ? 294 THR A N   1 
ATOM   2173  C  CA  . THR A 1 294 ? 6.804   35.130  14.036  1.00 24.33  ? 294 THR A CA  1 
ATOM   2174  C  C   . THR A 1 294 ? 5.937   34.146  14.820  1.00 22.84  ? 294 THR A C   1 
ATOM   2175  O  O   . THR A 1 294 ? 5.888   32.976  14.475  1.00 20.77  ? 294 THR A O   1 
ATOM   2176  C  CB  . THR A 1 294 ? 6.277   35.230  12.617  1.00 23.92  ? 294 THR A CB  1 
ATOM   2177  O  OG1 . THR A 1 294 ? 7.078   36.254  12.099  1.00 28.55  ? 294 THR A OG1 1 
ATOM   2178  C  CG2 . THR A 1 294 ? 4.891   35.824  12.558  1.00 27.08  ? 294 THR A CG2 1 
ATOM   2179  N  N   . ALA A 1 295 ? 5.253   34.665  15.848  1.00 25.20  ? 295 ALA A N   1 
ATOM   2180  C  CA  . ALA A 1 295 ? 4.292   33.894  16.598  1.00 26.88  ? 295 ALA A CA  1 
ATOM   2181  C  C   . ALA A 1 295 ? 2.992   33.818  15.819  1.00 24.28  ? 295 ALA A C   1 
ATOM   2182  O  O   . ALA A 1 295 ? 2.453   34.828  15.447  1.00 22.95  ? 295 ALA A O   1 
ATOM   2183  C  CB  . ALA A 1 295 ? 4.085   34.578  17.904  1.00 33.55  ? 295 ALA A CB  1 
ATOM   2184  N  N   . VAL A 1 296 ? 2.484   32.612  15.592  1.00 25.09  ? 296 VAL A N   1 
ATOM   2185  C  CA  . VAL A 1 296 ? 1.204   32.458  14.925  1.00 24.83  ? 296 VAL A CA  1 
ATOM   2186  C  C   . VAL A 1 296 ? 0.135   31.816  15.822  1.00 27.28  ? 296 VAL A C   1 
ATOM   2187  O  O   . VAL A 1 296 ? -1.008  31.764  15.404  1.00 27.37  ? 296 VAL A O   1 
ATOM   2188  C  CB  . VAL A 1 296 ? 1.415   31.688  13.623  1.00 24.22  ? 296 VAL A CB  1 
ATOM   2189  C  CG1 . VAL A 1 296 ? 2.531   32.324  12.836  1.00 24.27  ? 296 VAL A CG1 1 
ATOM   2190  C  CG2 . VAL A 1 296 ? 1.699   30.236  13.851  1.00 25.17  ? 296 VAL A CG2 1 
ATOM   2191  N  N   . THR A 1 297 ? 0.466   31.374  17.045  1.00 23.98  ? 297 THR A N   1 
ATOM   2192  C  CA  . THR A 1 297 ? -0.523  31.027  18.042  1.00 21.38  ? 297 THR A CA  1 
ATOM   2193  C  C   . THR A 1 297 ? -0.099  31.597  19.382  1.00 21.03  ? 297 THR A C   1 
ATOM   2194  O  O   . THR A 1 297 ? 1.017   31.994  19.593  1.00 19.39  ? 297 THR A O   1 
ATOM   2195  C  CB  . THR A 1 297 ? -0.725  29.527  18.198  1.00 21.59  ? 297 THR A CB  1 
ATOM   2196  O  OG1 . THR A 1 297 ? 0.426   28.932  18.801  1.00 20.43  ? 297 THR A OG1 1 
ATOM   2197  C  CG2 . THR A 1 297 ? -1.077  28.869  16.896  1.00 21.26  ? 297 THR A CG2 1 
ATOM   2198  N  N   . GLY A 1 298 ? -1.054  31.632  20.299  1.00 25.37  ? 298 GLY A N   1 
ATOM   2199  C  CA  . GLY A 1 298 ? -0.835  32.098  21.663  1.00 27.25  ? 298 GLY A CA  1 
ATOM   2200  C  C   . GLY A 1 298 ? -1.966  31.632  22.562  1.00 23.77  ? 298 GLY A C   1 
ATOM   2201  O  O   . GLY A 1 298 ? -3.086  31.991  22.331  1.00 24.92  ? 298 GLY A O   1 
ATOM   2202  N  N   . SER A 1 299 ? -1.699  30.795  23.560  1.00 26.64  ? 299 SER A N   1 
ATOM   2203  C  CA  . SER A 1 299 ? -2.729  30.328  24.475  1.00 21.39  ? 299 SER A CA  1 
ATOM   2204  C  C   . SER A 1 299 ? -2.121  30.116  25.867  1.00 24.07  ? 299 SER A C   1 
ATOM   2205  O  O   . SER A 1 299 ? -0.911  29.870  25.980  1.00 18.99  ? 299 SER A O   1 
ATOM   2206  C  CB  . SER A 1 299 ? -3.360  29.056  24.008  1.00 19.68  ? 299 SER A CB  1 
ATOM   2207  O  OG  . SER A 1 299 ? -3.809  29.155  22.677  1.00 21.26  ? 299 SER A OG  1 
ATOM   2208  N  N   . LEU A 1 300 ? -3.001  30.190  26.890  1.00 21.05  ? 300 LEU A N   1 
ATOM   2209  C  CA  . LEU A 1 300 ? -2.650  29.977  28.272  1.00 19.33  ? 300 LEU A CA  1 
ATOM   2210  C  C   . LEU A 1 300 ? -3.540  28.918  28.868  1.00 19.07  ? 300 LEU A C   1 
ATOM   2211  O  O   . LEU A 1 300 ? -4.732  28.946  28.659  1.00 22.41  ? 300 LEU A O   1 
ATOM   2212  C  CB  . LEU A 1 300 ? -2.752  31.286  29.017  1.00 21.09  ? 300 LEU A CB  1 
ATOM   2213  C  CG  . LEU A 1 300 ? -2.129  31.331  30.426  1.00 21.60  ? 300 LEU A CG  1 
ATOM   2214  C  CD1 . LEU A 1 300 ? -1.991  32.747  30.808  1.00 22.63  ? 300 LEU A CD1 1 
ATOM   2215  C  CD2 . LEU A 1 300 ? -3.007  30.691  31.450  1.00 24.47  ? 300 LEU A CD2 1 
ATOM   2216  N  N   . PHE A 1 301 ? -2.951  27.996  29.620  1.00 17.71  ? 301 PHE A N   1 
ATOM   2217  C  CA  . PHE A 1 301 ? -3.672  26.896  30.194  1.00 19.33  ? 301 PHE A CA  1 
ATOM   2218  C  C   . PHE A 1 301 ? -3.217  26.699  31.623  1.00 19.85  ? 301 PHE A C   1 
ATOM   2219  O  O   . PHE A 1 301 ? -2.098  27.025  32.006  1.00 21.90  ? 301 PHE A O   1 
ATOM   2220  C  CB  . PHE A 1 301 ? -3.428  25.568  29.482  1.00 20.49  ? 301 PHE A CB  1 
ATOM   2221  C  CG  . PHE A 1 301 ? -3.719  25.634  28.008  1.00 19.47  ? 301 PHE A CG  1 
ATOM   2222  C  CD1 . PHE A 1 301 ? -2.797  26.114  27.106  1.00 18.81  ? 301 PHE A CD1 1 
ATOM   2223  C  CD2 . PHE A 1 301 ? -4.968  25.315  27.536  1.00 24.46  ? 301 PHE A CD2 1 
ATOM   2224  C  CE1 . PHE A 1 301 ? -3.096  26.192  25.775  1.00 21.31  ? 301 PHE A CE1 1 
ATOM   2225  C  CE2 . PHE A 1 301 ? -5.271  25.399  26.175  1.00 21.58  ? 301 PHE A CE2 1 
ATOM   2226  C  CZ  . PHE A 1 301 ? -4.336  25.824  25.318  1.00 21.07  ? 301 PHE A CZ  1 
ATOM   2227  N  N   . PHE A 1 302 ? -4.178  26.228  32.432  1.00 23.97  ? 302 PHE A N   1 
ATOM   2228  C  CA  . PHE A 1 302 ? -3.880  25.749  33.782  1.00 22.76  ? 302 PHE A CA  1 
ATOM   2229  C  C   . PHE A 1 302 ? -3.810  24.225  33.760  1.00 21.26  ? 302 PHE A C   1 
ATOM   2230  O  O   . PHE A 1 302 ? -4.702  23.566  33.233  1.00 24.04  ? 302 PHE A O   1 
ATOM   2231  C  CB  . PHE A 1 302 ? -4.923  26.275  34.788  1.00 23.91  ? 302 PHE A CB  1 
ATOM   2232  C  CG  . PHE A 1 302 ? -4.640  25.833  36.209  1.00 20.16  ? 302 PHE A CG  1 
ATOM   2233  C  CD1 . PHE A 1 302 ? -3.627  26.477  36.914  1.00 23.02  ? 302 PHE A CD1 1 
ATOM   2234  C  CD2 . PHE A 1 302 ? -5.307  24.745  36.780  1.00 18.22  ? 302 PHE A CD2 1 
ATOM   2235  C  CE1 . PHE A 1 302 ? -3.308  26.060  38.223  1.00 24.13  ? 302 PHE A CE1 1 
ATOM   2236  C  CE2 . PHE A 1 302 ? -4.964  24.307  38.041  1.00 19.26  ? 302 PHE A CE2 1 
ATOM   2237  C  CZ  . PHE A 1 302 ? -3.996  24.992  38.786  1.00 19.60  ? 302 PHE A CZ  1 
ATOM   2238  N  N   . THR A 1 303 ? -2.734  23.675  34.280  1.00 20.11  ? 303 THR A N   1 
ATOM   2239  C  CA  . THR A 1 303 ? -2.542  22.235  34.308  1.00 22.78  ? 303 THR A CA  1 
ATOM   2240  C  C   . THR A 1 303 ? -2.730  21.795  35.755  1.00 22.91  ? 303 THR A C   1 
ATOM   2241  O  O   . THR A 1 303 ? -1.848  21.988  36.586  1.00 20.97  ? 303 THR A O   1 
ATOM   2242  C  CB  . THR A 1 303 ? -1.156  21.813  33.758  1.00 25.36  ? 303 THR A CB  1 
ATOM   2243  O  OG1 . THR A 1 303 ? -0.070  22.383  34.489  1.00 23.31  ? 303 THR A OG1 1 
ATOM   2244  C  CG2 . THR A 1 303 ? -0.929  22.294  32.333  1.00 23.01  ? 303 THR A CG2 1 
ATOM   2245  N  N   . PRO A 1 304 ? -3.891  21.215  36.095  1.00 22.07  ? 304 PRO A N   1 
ATOM   2246  C  CA  . PRO A 1 304 ? -4.182  20.854  37.458  1.00 25.74  ? 304 PRO A CA  1 
ATOM   2247  C  C   . PRO A 1 304 ? -3.310  19.744  37.982  1.00 23.92  ? 304 PRO A C   1 
ATOM   2248  O  O   . PRO A 1 304 ? -2.774  18.973  37.196  1.00 23.18  ? 304 PRO A O   1 
ATOM   2249  C  CB  . PRO A 1 304 ? -5.651  20.387  37.443  1.00 28.08  ? 304 PRO A CB  1 
ATOM   2250  C  CG  . PRO A 1 304 ? -6.162  20.710  36.083  1.00 26.75  ? 304 PRO A CG  1 
ATOM   2251  C  CD  . PRO A 1 304 ? -5.003  20.926  35.194  1.00 24.10  ? 304 PRO A CD  1 
ATOM   2252  N  N   . ALA A 1 305 ? -3.305  19.636  39.315  1.00 22.01  ? 305 ALA A N   1 
ATOM   2253  C  CA  . ALA A 1 305 ? -2.811  18.468  39.992  1.00 20.68  ? 305 ALA A CA  1 
ATOM   2254  C  C   . ALA A 1 305 ? -3.529  17.230  39.488  1.00 24.22  ? 305 ALA A C   1 
ATOM   2255  O  O   . ALA A 1 305 ? -4.686  17.284  39.082  1.00 30.13  ? 305 ALA A O   1 
ATOM   2256  C  CB  . ALA A 1 305 ? -2.961  18.616  41.454  1.00 22.13  ? 305 ALA A CB  1 
ATOM   2257  N  N   . ALA A 1 306 ? -2.774  16.130  39.414  1.00 25.50  ? 306 ALA A N   1 
ATOM   2258  C  CA  . ALA A 1 306 ? -3.275  14.857  38.932  1.00 28.99  ? 306 ALA A CA  1 
ATOM   2259  C  C   . ALA A 1 306 ? -4.545  14.438  39.678  1.00 31.36  ? 306 ALA A C   1 
ATOM   2260  O  O   . ALA A 1 306 ? -5.461  13.936  39.035  1.00 33.16  ? 306 ALA A O   1 
ATOM   2261  C  CB  . ALA A 1 306 ? -2.185  13.793  39.049  1.00 25.99  ? 306 ALA A CB  1 
ATOM   2262  N  N   . ASP A 1 307 ? -4.576  14.630  41.006  1.00 39.00  ? 307 ASP A N   1 
ATOM   2263  C  CA  . ASP A 1 307 ? -5.706  14.200  41.831  1.00 42.68  ? 307 ASP A CA  1 
ATOM   2264  C  C   . ASP A 1 307 ? -6.957  14.975  41.464  1.00 42.49  ? 307 ASP A C   1 
ATOM   2265  O  O   . ASP A 1 307 ? -8.030  14.368  41.469  1.00 48.67  ? 307 ASP A O   1 
ATOM   2266  C  CB  . ASP A 1 307 ? -5.494  14.189  43.344  1.00 51.78  ? 307 ASP A CB  1 
ATOM   2267  C  CG  . ASP A 1 307 ? -4.205  14.796  43.879  1.00 60.30  ? 307 ASP A CG  1 
ATOM   2268  O  OD1 . ASP A 1 307 ? -4.119  16.042  43.941  1.00 72.14  ? 307 ASP A OD1 1 
ATOM   2269  O  OD2 . ASP A 1 307 ? -3.284  14.012  44.190  1.00 73.64  ? 307 ASP A OD2 1 
ATOM   2270  N  N   . PHE A 1 308 ? -6.830  16.266  41.093  1.00 40.13  ? 308 PHE A N   1 
ATOM   2271  C  CA  . PHE A 1 308 ? -7.998  17.047  40.691  1.00 31.87  ? 308 PHE A CA  1 
ATOM   2272  C  C   . PHE A 1 308 ? -8.673  16.357  39.500  1.00 35.59  ? 308 PHE A C   1 
ATOM   2273  O  O   . PHE A 1 308 ? -9.883  16.239  39.471  1.00 35.74  ? 308 PHE A O   1 
ATOM   2274  C  CB  . PHE A 1 308 ? -7.621  18.503  40.446  1.00 29.84  ? 308 PHE A CB  1 
ATOM   2275  C  CG  . PHE A 1 308 ? -8.770  19.342  39.931  1.00 31.90  ? 308 PHE A CG  1 
ATOM   2276  C  CD1 . PHE A 1 308 ? -9.118  19.334  38.595  1.00 35.28  ? 308 PHE A CD1 1 
ATOM   2277  C  CD2 . PHE A 1 308 ? -9.512  20.135  40.781  1.00 41.46  ? 308 PHE A CD2 1 
ATOM   2278  C  CE1 . PHE A 1 308 ? -10.185 20.106  38.129  1.00 41.52  ? 308 PHE A CE1 1 
ATOM   2279  C  CE2 . PHE A 1 308 ? -10.566 20.921  40.314  1.00 41.72  ? 308 PHE A CE2 1 
ATOM   2280  C  CZ  . PHE A 1 308 ? -10.874 20.928  38.989  1.00 40.98  ? 308 PHE A CZ  1 
ATOM   2281  N  N   . LEU A 1 309 ? -7.906  15.827  38.539  1.00 33.37  ? 309 LEU A N   1 
ATOM   2282  C  CA  . LEU A 1 309 ? -8.506  15.193  37.380  1.00 38.41  ? 309 LEU A CA  1 
ATOM   2283  C  C   . LEU A 1 309 ? -9.068  13.805  37.722  1.00 39.93  ? 309 LEU A C   1 
ATOM   2284  O  O   . LEU A 1 309 ? -10.063 13.427  37.119  1.00 41.75  ? 309 LEU A O   1 
ATOM   2285  C  CB  . LEU A 1 309 ? -7.522  15.093  36.217  1.00 34.83  ? 309 LEU A CB  1 
ATOM   2286  C  CG  . LEU A 1 309 ? -6.823  16.380  35.777  1.00 33.14  ? 309 LEU A CG  1 
ATOM   2287  C  CD1 . LEU A 1 309 ? -5.728  15.812  34.917  1.00 46.54  ? 309 LEU A CD1 1 
ATOM   2288  C  CD2 . LEU A 1 309 ? -7.583  17.348  34.991  1.00 30.22  ? 309 LEU A CD2 1 
ATOM   2289  N  N   . GLU A 1 310 ? -8.413  13.029  38.611  1.00 48.08  ? 310 GLU A N   1 
ATOM   2290  C  CA  . GLU A 1 310 ? -8.838  11.668  38.958  1.00 50.14  ? 310 GLU A CA  1 
ATOM   2291  C  C   . GLU A 1 310 ? -10.248 11.780  39.531  1.00 48.43  ? 310 GLU A C   1 
ATOM   2292  O  O   . GLU A 1 310 ? -11.100 11.031  39.104  1.00 56.05  ? 310 GLU A O   1 
ATOM   2293  C  CB  . GLU A 1 310 ? -7.828  10.926  39.853  1.00 64.10  ? 310 GLU A CB  1 
ATOM   2294  C  CG  . GLU A 1 310 ? -8.009  9.411   39.979  1.00 76.11  ? 310 GLU A CG  1 
ATOM   2295  C  CD  . GLU A 1 310 ? -6.919  8.717   40.805  1.00 92.96  ? 310 GLU A CD  1 
ATOM   2296  O  OE1 . GLU A 1 310 ? -6.317  7.778   40.256  1.00 94.07  ? 310 GLU A OE1 1 
ATOM   2297  O  OE2 . GLU A 1 310 ? -6.643  9.078   41.983  1.00 113.21 ? 310 GLU A OE2 1 
ATOM   2298  N  N   . ASP A 1 311 ? -10.544 12.812  40.345  1.00 54.45  ? 311 ASP A N   1 
ATOM   2299  C  CA  . ASP A 1 311 ? -11.758 12.850  41.155  1.00 60.39  ? 311 ASP A CA  1 
ATOM   2300  C  C   . ASP A 1 311 ? -12.908 13.512  40.401  1.00 58.87  ? 311 ASP A C   1 
ATOM   2301  O  O   . ASP A 1 311 ? -13.382 14.505  40.906  1.00 64.17  ? 311 ASP A O   1 
ATOM   2302  C  CB  . ASP A 1 311 ? -11.602 13.658  42.451  1.00 64.44  ? 311 ASP A CB  1 
ATOM   2303  C  CG  . ASP A 1 311 ? -10.589 13.217  43.514  1.00 78.00  ? 311 ASP A CG  1 
ATOM   2304  O  OD1 . ASP A 1 311 ? -9.977  12.115  43.420  1.00 82.59  ? 311 ASP A OD1 1 
ATOM   2305  O  OD2 . ASP A 1 311 ? -10.380 14.007  44.454  1.00 69.96  ? 311 ASP A OD2 1 
ATOM   2306  N  N   . LEU A 1 312 ? -13.417 13.001  39.265  1.00 68.54  ? 312 LEU A N   1 
ATOM   2307  C  CA  . LEU A 1 312 ? -14.431 13.773  38.532  1.00 78.60  ? 312 LEU A CA  1 
ATOM   2308  C  C   . LEU A 1 312 ? -15.704 12.928  38.306  1.00 68.48  ? 312 LEU A C   1 
ATOM   2309  O  O   . LEU A 1 312 ? -15.509 11.789  37.858  1.00 59.35  ? 312 LEU A O   1 
ATOM   2310  C  CB  . LEU A 1 312 ? -13.889 14.411  37.234  1.00 72.07  ? 312 LEU A CB  1 
ATOM   2311  C  CG  . LEU A 1 312 ? -12.958 15.634  37.367  1.00 57.47  ? 312 LEU A CG  1 
ATOM   2312  C  CD1 . LEU A 1 312 ? -12.590 16.259  36.047  1.00 53.45  ? 312 LEU A CD1 1 
ATOM   2313  C  CD2 . LEU A 1 312 ? -13.547 16.763  38.176  1.00 53.87  ? 312 LEU A CD2 1 
ATOM   2314  N  N   . GLU B 1 7   ? 24.662  -20.463 -5.539  1.00 77.11  ? 7   GLU B N   1 
ATOM   2315  C  CA  . GLU B 1 7   ? 23.828  -21.533 -4.908  1.00 91.26  ? 7   GLU B CA  1 
ATOM   2316  C  C   . GLU B 1 7   ? 23.748  -21.147 -3.402  1.00 95.46  ? 7   GLU B C   1 
ATOM   2317  O  O   . GLU B 1 7   ? 23.373  -20.018 -3.103  1.00 62.10  ? 7   GLU B O   1 
ATOM   2318  C  CB  . GLU B 1 7   ? 24.168  -22.936 -5.494  1.00 58.85  ? 7   GLU B CB  1 
ATOM   2319  N  N   . PRO B 1 8   ? 24.181  -21.934 -2.373  1.00 86.30  ? 8   PRO B N   1 
ATOM   2320  C  CA  . PRO B 1 8   ? 23.270  -22.223 -1.251  1.00 72.52  ? 8   PRO B CA  1 
ATOM   2321  C  C   . PRO B 1 8   ? 23.320  -21.284 -0.018  1.00 68.66  ? 8   PRO B C   1 
ATOM   2322  O  O   . PRO B 1 8   ? 24.422  -20.914 0.379   1.00 57.20  ? 8   PRO B O   1 
ATOM   2323  C  CB  . PRO B 1 8   ? 23.750  -23.699 -1.043  1.00 67.83  ? 8   PRO B CB  1 
ATOM   2324  C  CG  . PRO B 1 8   ? 25.276  -23.604 -1.236  1.00 72.26  ? 8   PRO B CG  1 
ATOM   2325  C  CD  . PRO B 1 8   ? 25.568  -22.405 -2.150  1.00 68.52  ? 8   PRO B CD  1 
ATOM   2326  N  N   . GLU B 1 9   ? 22.143  -20.831 0.532   1.00 60.95  ? 9   GLU B N   1 
ATOM   2327  C  CA  . GLU B 1 9   ? 22.030  -20.022 1.764   1.00 55.20  ? 9   GLU B CA  1 
ATOM   2328  C  C   . GLU B 1 9   ? 22.205  -21.056 2.894   1.00 57.66  ? 9   GLU B C   1 
ATOM   2329  O  O   . GLU B 1 9   ? 21.461  -22.059 2.987   1.00 45.51  ? 9   GLU B O   1 
ATOM   2330  C  CB  . GLU B 1 9   ? 20.896  -18.960 1.909   1.00 42.18  ? 9   GLU B CB  1 
ATOM   2331  N  N   . PRO B 1 10  ? 23.284  -20.957 3.729   1.00 51.37  ? 10  PRO B N   1 
ATOM   2332  C  CA  . PRO B 1 10  ? 23.417  -21.806 4.919   1.00 51.84  ? 10  PRO B CA  1 
ATOM   2333  C  C   . PRO B 1 10  ? 22.439  -21.403 6.014   1.00 46.66  ? 10  PRO B C   1 
ATOM   2334  O  O   . PRO B 1 10  ? 21.905  -20.278 5.948   1.00 29.47  ? 10  PRO B O   1 
ATOM   2335  C  CB  . PRO B 1 10  ? 24.867  -21.573 5.352   1.00 47.45  ? 10  PRO B CB  1 
ATOM   2336  C  CG  . PRO B 1 10  ? 25.132  -20.176 4.934   1.00 40.30  ? 10  PRO B CG  1 
ATOM   2337  C  CD  . PRO B 1 10  ? 24.451  -20.083 3.576   1.00 38.88  ? 10  PRO B CD  1 
ATOM   2338  N  N   . GLN B 1 11  ? 22.240  -22.322 6.998   1.00 43.24  ? 11  GLN B N   1 
ATOM   2339  C  CA  . GLN B 1 11  ? 21.504  -21.933 8.199   1.00 31.83  ? 11  GLN B CA  1 
ATOM   2340  C  C   . GLN B 1 11  ? 22.348  -20.933 8.994   1.00 32.65  ? 11  GLN B C   1 
ATOM   2341  O  O   . GLN B 1 11  ? 23.486  -20.641 8.579   1.00 28.00  ? 11  GLN B O   1 
ATOM   2342  C  CB  . GLN B 1 11  ? 21.096  -23.133 9.017   1.00 29.08  ? 11  GLN B CB  1 
ATOM   2343  C  CG  . GLN B 1 11  ? 20.036  -23.969 8.351   1.00 27.68  ? 11  GLN B CG  1 
ATOM   2344  C  CD  . GLN B 1 11  ? 19.602  -25.038 9.301   1.00 29.91  ? 11  GLN B CD  1 
ATOM   2345  O  OE1 . GLN B 1 11  ? 19.047  -24.757 10.356  1.00 27.79  ? 11  GLN B OE1 1 
ATOM   2346  N  NE2 . GLN B 1 11  ? 19.894  -26.267 8.948   1.00 37.38  ? 11  GLN B NE2 1 
ATOM   2347  N  N   . MET B 1 12  ? 21.824  -20.447 10.128  1.00 31.07  ? 12  MET B N   1 
ATOM   2348  C  CA  . MET B 1 12  ? 22.499  -19.361 10.839  1.00 40.44  ? 12  MET B CA  1 
ATOM   2349  C  C   . MET B 1 12  ? 23.575  -19.948 11.771  1.00 35.23  ? 12  MET B C   1 
ATOM   2350  O  O   . MET B 1 12  ? 23.647  -19.675 12.961  1.00 26.21  ? 12  MET B O   1 
ATOM   2351  C  CB  . MET B 1 12  ? 21.462  -18.464 11.548  1.00 52.72  ? 12  MET B CB  1 
ATOM   2352  C  CG  . MET B 1 12  ? 22.033  -17.225 12.258  1.00 65.00  ? 12  MET B CG  1 
ATOM   2353  S  SD  . MET B 1 12  ? 22.509  -15.981 11.059  1.00 69.53  ? 12  MET B SD  1 
ATOM   2354  C  CE  . MET B 1 12  ? 22.271  -16.525 9.351   1.00 61.24  ? 12  MET B CE  1 
ATOM   2355  N  N   . VAL B 1 13  ? 24.473  -20.723 11.195  1.00 40.73  ? 13  VAL B N   1 
ATOM   2356  C  CA  . VAL B 1 13  ? 25.504  -21.366 11.972  1.00 35.18  ? 13  VAL B CA  1 
ATOM   2357  C  C   . VAL B 1 13  ? 26.447  -20.327 12.549  1.00 33.40  ? 13  VAL B C   1 
ATOM   2358  O  O   . VAL B 1 13  ? 26.758  -20.435 13.717  1.00 34.84  ? 13  VAL B O   1 
ATOM   2359  C  CB  . VAL B 1 13  ? 26.220  -22.444 11.151  1.00 38.07  ? 13  VAL B CB  1 
ATOM   2360  C  CG1 . VAL B 1 13  ? 27.364  -23.016 11.958  1.00 46.33  ? 13  VAL B CG1 1 
ATOM   2361  C  CG2 . VAL B 1 13  ? 25.267  -23.588 10.793  1.00 40.91  ? 13  VAL B CG2 1 
ATOM   2362  N  N   . LEU B 1 14  ? 26.873  -19.343 11.748  1.00 33.24  ? 14  LEU B N   1 
ATOM   2363  C  CA  . LEU B 1 14  ? 27.743  -18.269 12.213  1.00 40.59  ? 14  LEU B CA  1 
ATOM   2364  C  C   . LEU B 1 14  ? 26.866  -17.174 12.776  1.00 45.60  ? 14  LEU B C   1 
ATOM   2365  O  O   . LEU B 1 14  ? 26.315  -16.392 12.037  1.00 59.10  ? 14  LEU B O   1 
ATOM   2366  C  CB  . LEU B 1 14  ? 28.571  -17.710 11.066  1.00 46.01  ? 14  LEU B CB  1 
ATOM   2367  C  CG  . LEU B 1 14  ? 29.197  -18.776 10.166  1.00 51.06  ? 14  LEU B CG  1 
ATOM   2368  C  CD1 . LEU B 1 14  ? 29.606  -18.262 8.840   1.00 53.55  ? 14  LEU B CD1 1 
ATOM   2369  C  CD2 . LEU B 1 14  ? 30.427  -19.355 10.829  1.00 72.09  ? 14  LEU B CD2 1 
ATOM   2370  N  N   . SER B 1 15  ? 26.599  -17.206 14.063  1.00 50.31  ? 15  SER B N   1 
ATOM   2371  C  CA  . SER B 1 15  ? 25.617  -16.287 14.589  1.00 48.88  ? 15  SER B CA  1 
ATOM   2372  C  C   . SER B 1 15  ? 26.409  -15.236 15.349  1.00 47.70  ? 15  SER B C   1 
ATOM   2373  O  O   . SER B 1 15  ? 27.487  -15.515 15.856  1.00 44.77  ? 15  SER B O   1 
ATOM   2374  C  CB  . SER B 1 15  ? 24.567  -17.029 15.423  1.00 52.14  ? 15  SER B CB  1 
ATOM   2375  O  OG  . SER B 1 15  ? 24.008  -16.177 16.412  1.00 55.70  ? 15  SER B OG  1 
ATOM   2376  N  N   . PRO B 1 16  ? 25.970  -13.964 15.390  1.00 61.20  ? 16  PRO B N   1 
ATOM   2377  C  CA  . PRO B 1 16  ? 26.392  -13.059 16.461  1.00 59.11  ? 16  PRO B CA  1 
ATOM   2378  C  C   . PRO B 1 16  ? 26.455  -13.768 17.804  1.00 54.41  ? 16  PRO B C   1 
ATOM   2379  O  O   . PRO B 1 16  ? 25.799  -14.785 17.996  1.00 57.78  ? 16  PRO B O   1 
ATOM   2380  C  CB  . PRO B 1 16  ? 25.297  -11.988 16.491  1.00 59.97  ? 16  PRO B CB  1 
ATOM   2381  C  CG  . PRO B 1 16  ? 24.378  -12.302 15.310  1.00 57.88  ? 16  PRO B CG  1 
ATOM   2382  C  CD  . PRO B 1 16  ? 25.068  -13.324 14.419  1.00 60.73  ? 16  PRO B CD  1 
ATOM   2383  N  N   . LEU B 1 17  ? 27.248  -13.195 18.711  1.00 52.82  ? 17  LEU B N   1 
ATOM   2384  C  CA  . LEU B 1 17  ? 27.256  -13.526 20.122  1.00 59.32  ? 17  LEU B CA  1 
ATOM   2385  C  C   . LEU B 1 17  ? 25.813  -13.378 20.655  1.00 55.56  ? 17  LEU B C   1 
ATOM   2386  O  O   . LEU B 1 17  ? 25.118  -12.399 20.334  1.00 44.54  ? 17  LEU B O   1 
ATOM   2387  C  CB  . LEU B 1 17  ? 28.245  -12.595 20.851  1.00 66.14  ? 17  LEU B CB  1 
ATOM   2388  C  CG  . LEU B 1 17  ? 29.751  -12.806 20.640  1.00 71.74  ? 17  LEU B CG  1 
ATOM   2389  C  CD1 . LEU B 1 17  ? 30.533  -11.967 21.713  1.00 66.19  ? 17  LEU B CD1 1 
ATOM   2390  C  CD2 . LEU B 1 17  ? 30.146  -14.317 20.616  1.00 63.38  ? 17  LEU B CD2 1 
ATOM   2391  N  N   . THR B 1 18  ? 25.342  -14.424 21.363  1.00 43.25  ? 18  THR B N   1 
ATOM   2392  C  CA  . THR B 1 18  ? 24.010  -14.483 21.931  1.00 40.61  ? 18  THR B CA  1 
ATOM   2393  C  C   . THR B 1 18  ? 24.194  -14.914 23.380  1.00 34.36  ? 18  THR B C   1 
ATOM   2394  O  O   . THR B 1 18  ? 25.072  -15.692 23.689  1.00 34.45  ? 18  THR B O   1 
ATOM   2395  C  CB  . THR B 1 18  ? 23.090  -15.458 21.178  1.00 39.75  ? 18  THR B CB  1 
ATOM   2396  O  OG1 . THR B 1 18  ? 23.767  -16.719 21.103  1.00 46.58  ? 18  THR B OG1 1 
ATOM   2397  C  CG2 . THR B 1 18  ? 22.703  -14.948 19.794  1.00 36.99  ? 18  THR B CG2 1 
ATOM   2398  N  N   . SER B 1 19  ? 23.371  -14.403 24.289  1.00 29.90  ? 19  SER B N   1 
ATOM   2399  C  CA  . SER B 1 19  ? 23.523  -14.717 25.688  1.00 28.09  ? 19  SER B CA  1 
ATOM   2400  C  C   . SER B 1 19  ? 22.515  -15.781 26.138  1.00 29.88  ? 19  SER B C   1 
ATOM   2401  O  O   . SER B 1 19  ? 22.622  -16.229 27.274  1.00 24.25  ? 19  SER B O   1 
ATOM   2402  C  CB  . SER B 1 19  ? 23.474  -13.474 26.477  1.00 31.15  ? 19  SER B CB  1 
ATOM   2403  O  OG  . SER B 1 19  ? 22.579  -12.637 25.790  1.00 38.58  ? 19  SER B OG  1 
ATOM   2404  N  N   . ALA B 1 20  ? 21.591  -16.246 25.263  1.00 24.29  ? 20  ALA B N   1 
ATOM   2405  C  CA  . ALA B 1 20  ? 20.637  -17.255 25.693  1.00 24.68  ? 20  ALA B CA  1 
ATOM   2406  C  C   . ALA B 1 20  ? 20.478  -18.310 24.621  1.00 24.69  ? 20  ALA B C   1 
ATOM   2407  O  O   . ALA B 1 20  ? 20.593  -17.968 23.442  1.00 25.69  ? 20  ALA B O   1 
ATOM   2408  C  CB  . ALA B 1 20  ? 19.313  -16.611 25.965  1.00 26.24  ? 20  ALA B CB  1 
ATOM   2409  N  N   . ALA B 1 21  ? 20.193  -19.545 25.043  1.00 19.74  ? 21  ALA B N   1 
ATOM   2410  C  CA  . ALA B 1 21  ? 20.004  -20.595 24.069  1.00 22.28  ? 21  ALA B CA  1 
ATOM   2411  C  C   . ALA B 1 21  ? 19.096  -21.652 24.648  1.00 25.45  ? 21  ALA B C   1 
ATOM   2412  O  O   . ALA B 1 21  ? 19.080  -21.808 25.867  1.00 26.43  ? 21  ALA B O   1 
ATOM   2413  C  CB  . ALA B 1 21  ? 21.278  -21.242 23.661  1.00 21.22  ? 21  ALA B CB  1 
ATOM   2414  N  N   . ILE B 1 22  ? 18.323  -22.285 23.743  1.00 24.94  ? 22  ILE B N   1 
ATOM   2415  C  CA  . ILE B 1 22  ? 17.636  -23.510 24.060  1.00 22.40  ? 22  ILE B CA  1 
ATOM   2416  C  C   . ILE B 1 22  ? 18.144  -24.582 23.126  1.00 21.36  ? 22  ILE B C   1 
ATOM   2417  O  O   . ILE B 1 22  ? 18.122  -24.397 21.929  1.00 22.69  ? 22  ILE B O   1 
ATOM   2418  C  CB  . ILE B 1 22  ? 16.122  -23.366 24.010  1.00 25.48  ? 22  ILE B CB  1 
ATOM   2419  C  CG1 . ILE B 1 22  ? 15.614  -22.521 25.179  1.00 22.97  ? 22  ILE B CG1 1 
ATOM   2420  C  CG2 . ILE B 1 22  ? 15.473  -24.759 24.008  1.00 29.44  ? 22  ILE B CG2 1 
ATOM   2421  C  CD1 . ILE B 1 22  ? 14.102  -22.306 25.171  1.00 21.95  ? 22  ILE B CD1 1 
ATOM   2422  N  N   . PHE B 1 23  ? 18.565  -25.699 23.717  1.00 22.46  ? 23  PHE B N   1 
ATOM   2423  C  CA  . PHE B 1 23  ? 18.919  -26.890 22.974  1.00 24.23  ? 23  PHE B CA  1 
ATOM   2424  C  C   . PHE B 1 23  ? 17.814  -27.913 23.165  1.00 24.39  ? 23  PHE B C   1 
ATOM   2425  O  O   . PHE B 1 23  ? 17.575  -28.289 24.273  1.00 22.65  ? 23  PHE B O   1 
ATOM   2426  C  CB  . PHE B 1 23  ? 20.225  -27.506 23.477  1.00 25.62  ? 23  PHE B CB  1 
ATOM   2427  C  CG  . PHE B 1 23  ? 21.381  -26.534 23.405  1.00 26.22  ? 23  PHE B CG  1 
ATOM   2428  C  CD1 . PHE B 1 23  ? 22.178  -26.459 22.269  1.00 23.25  ? 23  PHE B CD1 1 
ATOM   2429  C  CD2 . PHE B 1 23  ? 21.667  -25.720 24.514  1.00 28.17  ? 23  PHE B CD2 1 
ATOM   2430  C  CE1 . PHE B 1 23  ? 23.249  -25.585 22.236  1.00 24.94  ? 23  PHE B CE1 1 
ATOM   2431  C  CE2 . PHE B 1 23  ? 22.771  -24.871 24.496  1.00 26.58  ? 23  PHE B CE2 1 
ATOM   2432  C  CZ  . PHE B 1 23  ? 23.538  -24.787 23.351  1.00 25.02  ? 23  PHE B CZ  1 
ATOM   2433  N  N   . LEU B 1 24  ? 17.246  -28.399 22.064  1.00 26.00  ? 24  LEU B N   1 
ATOM   2434  C  CA  . LEU B 1 24  ? 16.162  -29.361 22.074  1.00 28.94  ? 24  LEU B CA  1 
ATOM   2435  C  C   . LEU B 1 24  ? 16.576  -30.548 21.213  1.00 27.93  ? 24  LEU B C   1 
ATOM   2436  O  O   . LEU B 1 24  ? 16.905  -30.385 20.041  1.00 27.08  ? 24  LEU B O   1 
ATOM   2437  C  CB  . LEU B 1 24  ? 15.003  -28.608 21.442  1.00 35.22  ? 24  LEU B CB  1 
ATOM   2438  C  CG  . LEU B 1 24  ? 13.686  -28.520 22.193  1.00 40.47  ? 24  LEU B CG  1 
ATOM   2439  C  CD1 . LEU B 1 24  ? 12.735  -27.934 21.150  1.00 42.75  ? 24  LEU B CD1 1 
ATOM   2440  C  CD2 . LEU B 1 24  ? 13.293  -29.876 22.712  1.00 42.03  ? 24  LEU B CD2 1 
ATOM   2441  N  N   . VAL B 1 25  ? 16.619  -31.742 21.813  1.00 31.56  ? 25  VAL B N   1 
ATOM   2442  C  CA  . VAL B 1 25  ? 16.941  -32.983 21.108  1.00 29.29  ? 25  VAL B CA  1 
ATOM   2443  C  C   . VAL B 1 25  ? 15.777  -33.937 21.236  1.00 26.88  ? 25  VAL B C   1 
ATOM   2444  O  O   . VAL B 1 25  ? 15.299  -34.165 22.342  1.00 30.06  ? 25  VAL B O   1 
ATOM   2445  C  CB  . VAL B 1 25  ? 18.183  -33.692 21.640  1.00 31.12  ? 25  VAL B CB  1 
ATOM   2446  C  CG1 . VAL B 1 25  ? 18.404  -34.988 20.842  1.00 31.01  ? 25  VAL B CG1 1 
ATOM   2447  C  CG2 . VAL B 1 25  ? 19.399  -32.753 21.607  1.00 30.90  ? 25  VAL B CG2 1 
ATOM   2448  N  N   . VAL B 1 26  ? 15.266  -34.390 20.093  1.00 26.28  ? 26  VAL B N   1 
ATOM   2449  C  CA  . VAL B 1 26  ? 14.103  -35.262 20.098  1.00 26.90  ? 26  VAL B CA  1 
ATOM   2450  C  C   . VAL B 1 26  ? 14.360  -36.480 19.198  1.00 27.69  ? 26  VAL B C   1 
ATOM   2451  O  O   . VAL B 1 26  ? 15.191  -36.469 18.286  1.00 26.17  ? 26  VAL B O   1 
ATOM   2452  C  CB  . VAL B 1 26  ? 12.845  -34.515 19.654  1.00 27.67  ? 26  VAL B CB  1 
ATOM   2453  C  CG1 . VAL B 1 26  ? 12.620  -33.303 20.513  1.00 31.28  ? 26  VAL B CG1 1 
ATOM   2454  C  CG2 . VAL B 1 26  ? 12.891  -34.115 18.177  1.00 28.04  ? 26  VAL B CG2 1 
ATOM   2455  N  N   . THR B 1 27  ? 13.622  -37.551 19.502  1.00 29.96  ? 27  THR B N   1 
ATOM   2456  C  CA  . THR B 1 27  ? 13.546  -38.704 18.614  1.00 31.46  ? 27  THR B CA  1 
ATOM   2457  C  C   . THR B 1 27  ? 12.190  -38.717 17.937  1.00 28.76  ? 27  THR B C   1 
ATOM   2458  O  O   . THR B 1 27  ? 11.210  -38.222 18.473  1.00 29.21  ? 27  THR B O   1 
ATOM   2459  C  CB  . THR B 1 27  ? 13.808  -40.028 19.318  1.00 27.14  ? 27  THR B CB  1 
ATOM   2460  O  OG1 . THR B 1 27  ? 12.950  -40.068 20.445  1.00 30.02  ? 27  THR B OG1 1 
ATOM   2461  C  CG2 . THR B 1 27  ? 15.264  -40.176 19.689  1.00 30.73  ? 27  THR B CG2 1 
ATOM   2462  N  N   . ILE B 1 28  ? 12.201  -39.243 16.719  1.00 32.81  ? 28  ILE B N   1 
ATOM   2463  C  CA  . ILE B 1 28  ? 11.005  -39.305 15.892  1.00 36.53  ? 28  ILE B CA  1 
ATOM   2464  C  C   . ILE B 1 28  ? 10.300  -40.639 16.151  1.00 36.85  ? 28  ILE B C   1 
ATOM   2465  O  O   . ILE B 1 28  ? 10.873  -41.713 16.041  1.00 38.77  ? 28  ILE B O   1 
ATOM   2466  C  CB  . ILE B 1 28  ? 11.374  -39.143 14.406  1.00 37.96  ? 28  ILE B CB  1 
ATOM   2467  C  CG1 . ILE B 1 28  ? 12.167  -37.860 14.110  1.00 33.22  ? 28  ILE B CG1 1 
ATOM   2468  C  CG2 . ILE B 1 28  ? 10.100  -39.214 13.587  1.00 38.53  ? 28  ILE B CG2 1 
ATOM   2469  C  CD1 . ILE B 1 28  ? 12.755  -37.822 12.716  1.00 33.03  ? 28  ILE B CD1 1 
ATOM   2470  N  N   . ASP B 1 29  ? 9.034   -40.558 16.536  1.00 39.30  ? 29  ASP B N   1 
ATOM   2471  C  CA  . ASP B 1 29  ? 8.296   -41.753 16.866  1.00 39.22  ? 29  ASP B CA  1 
ATOM   2472  C  C   . ASP B 1 29  ? 7.968   -42.453 15.544  1.00 52.65  ? 29  ASP B C   1 
ATOM   2473  O  O   . ASP B 1 29  ? 8.027   -41.869 14.444  1.00 50.13  ? 29  ASP B O   1 
ATOM   2474  C  CB  . ASP B 1 29  ? 7.045   -41.359 17.640  1.00 41.29  ? 29  ASP B CB  1 
ATOM   2475  C  CG  . ASP B 1 29  ? 7.241   -40.702 19.006  1.00 38.37  ? 29  ASP B CG  1 
ATOM   2476  O  OD1 . ASP B 1 29  ? 8.404   -40.604 19.467  1.00 39.45  ? 29  ASP B OD1 1 
ATOM   2477  O  OD2 . ASP B 1 29  ? 6.227   -40.354 19.617  1.00 36.46  ? 29  ASP B OD2 1 
ATOM   2478  N  N   . SER B 1 30  ? 7.598   -43.727 15.673  1.00 54.35  ? 30  SER B N   1 
ATOM   2479  C  CA  . SER B 1 30  ? 7.062   -44.479 14.569  1.00 44.95  ? 30  SER B CA  1 
ATOM   2480  C  C   . SER B 1 30  ? 5.862   -43.759 13.969  1.00 46.14  ? 30  SER B C   1 
ATOM   2481  O  O   . SER B 1 30  ? 4.916   -43.421 14.708  1.00 44.29  ? 30  SER B O   1 
ATOM   2482  C  CB  . SER B 1 30  ? 6.654   -45.774 15.125  1.00 45.51  ? 30  SER B CB  1 
ATOM   2483  O  OG  . SER B 1 30  ? 7.029   -46.685 14.120  1.00 57.08  ? 30  SER B OG  1 
ATOM   2484  N  N   . GLY B 1 31  ? 5.914   -43.493 12.663  1.00 39.17  ? 31  GLY B N   1 
ATOM   2485  C  CA  . GLY B 1 31  ? 4.777   -42.841 12.042  1.00 38.99  ? 31  GLY B CA  1 
ATOM   2486  C  C   . GLY B 1 31  ? 4.924   -41.325 11.988  1.00 49.10  ? 31  GLY B C   1 
ATOM   2487  O  O   . GLY B 1 31  ? 4.163   -40.678 11.276  1.00 46.23  ? 31  GLY B O   1 
ATOM   2488  N  N   . GLY B 1 32  ? 5.954   -40.777 12.667  1.00 48.91  ? 32  GLY B N   1 
ATOM   2489  C  CA  . GLY B 1 32  ? 6.062   -39.332 12.848  1.00 43.61  ? 32  GLY B CA  1 
ATOM   2490  C  C   . GLY B 1 32  ? 6.712   -38.618 11.661  1.00 41.67  ? 32  GLY B C   1 
ATOM   2491  O  O   . GLY B 1 32  ? 6.817   -37.385 11.632  1.00 44.89  ? 32  GLY B O   1 
ATOM   2492  N  N   . GLU B 1 33  ? 7.151   -39.382 10.658  1.00 44.89  ? 33  GLU B N   1 
ATOM   2493  C  CA  . GLU B 1 33  ? 8.085   -38.867 9.658   1.00 44.76  ? 33  GLU B CA  1 
ATOM   2494  C  C   . GLU B 1 33  ? 7.446   -37.739 8.860   1.00 41.39  ? 33  GLU B C   1 
ATOM   2495  O  O   . GLU B 1 33  ? 8.114   -36.786 8.507   1.00 44.64  ? 33  GLU B O   1 
ATOM   2496  C  CB  . GLU B 1 33  ? 8.565   -39.983 8.719   1.00 44.64  ? 33  GLU B CB  1 
ATOM   2497  C  CG  . GLU B 1 33  ? 9.418   -41.088 9.351   1.00 41.83  ? 33  GLU B CG  1 
ATOM   2498  C  CD  . GLU B 1 33  ? 8.712   -42.172 10.159  1.00 44.88  ? 33  GLU B CD  1 
ATOM   2499  O  OE1 . GLU B 1 33  ? 7.479   -42.237 10.265  1.00 44.89  ? 33  GLU B OE1 1 
ATOM   2500  O  OE2 . GLU B 1 33  ? 9.416   -42.949 10.795  1.00 58.57  ? 33  GLU B OE2 1 
ATOM   2501  N  N   . ASP B 1 34  ? 6.169   -37.869 8.502   1.00 40.82  ? 34  ASP B N   1 
ATOM   2502  C  CA  . ASP B 1 34  ? 5.517   -36.868 7.676   1.00 45.44  ? 34  ASP B CA  1 
ATOM   2503  C  C   . ASP B 1 34  ? 5.358   -35.556 8.445   1.00 39.10  ? 34  ASP B C   1 
ATOM   2504  O  O   . ASP B 1 34  ? 5.528   -34.473 7.903   1.00 37.80  ? 34  ASP B O   1 
ATOM   2505  C  CB  . ASP B 1 34  ? 4.137   -37.338 7.214   1.00 54.64  ? 34  ASP B CB  1 
ATOM   2506  C  CG  . ASP B 1 34  ? 4.145   -38.315 6.043   1.00 61.85  ? 34  ASP B CG  1 
ATOM   2507  O  OD1 . ASP B 1 34  ? 5.155   -38.376 5.306   1.00 57.49  ? 34  ASP B OD1 1 
ATOM   2508  O  OD2 . ASP B 1 34  ? 3.149   -39.035 5.889   1.00 73.98  ? 34  ASP B OD2 1 
ATOM   2509  N  N   . THR B 1 35  ? 4.963   -35.647 9.705   1.00 35.47  ? 35  THR B N   1 
ATOM   2510  C  CA  . THR B 1 35  ? 4.811   -34.434 10.481  1.00 34.36  ? 35  THR B CA  1 
ATOM   2511  C  C   . THR B 1 35  ? 6.144   -33.703 10.550  1.00 37.02  ? 35  THR B C   1 
ATOM   2512  O  O   . THR B 1 35  ? 6.194   -32.502 10.428  1.00 34.94  ? 35  THR B O   1 
ATOM   2513  C  CB  . THR B 1 35  ? 4.344   -34.752 11.884  1.00 33.91  ? 35  THR B CB  1 
ATOM   2514  O  OG1 . THR B 1 35  ? 3.072   -35.310 11.666  1.00 32.38  ? 35  THR B OG1 1 
ATOM   2515  C  CG2 . THR B 1 35  ? 4.113   -33.495 12.691  1.00 35.39  ? 35  THR B CG2 1 
ATOM   2516  N  N   . VAL B 1 36  ? 7.218   -34.448 10.751  1.00 35.02  ? 36  VAL B N   1 
ATOM   2517  C  CA  . VAL B 1 36  ? 8.541   -33.874 10.837  1.00 34.47  ? 36  VAL B CA  1 
ATOM   2518  C  C   . VAL B 1 36  ? 8.871   -33.166 9.540   1.00 37.81  ? 36  VAL B C   1 
ATOM   2519  O  O   . VAL B 1 36  ? 9.305   -32.027 9.584   1.00 30.83  ? 36  VAL B O   1 
ATOM   2520  C  CB  . VAL B 1 36  ? 9.612   -34.930 11.195  1.00 36.96  ? 36  VAL B CB  1 
ATOM   2521  C  CG1 . VAL B 1 36  ? 11.052  -34.424 10.963  1.00 37.94  ? 36  VAL B CG1 1 
ATOM   2522  C  CG2 . VAL B 1 36  ? 9.386   -35.411 12.621  1.00 36.20  ? 36  VAL B CG2 1 
ATOM   2523  N  N   . ARG B 1 37  ? 8.696   -33.841 8.397   1.00 43.95  ? 37  ARG B N   1 
ATOM   2524  C  CA  . ARG B 1 37  ? 8.992   -33.251 7.104   1.00 38.35  ? 37  ARG B CA  1 
ATOM   2525  C  C   . ARG B 1 37  ? 8.261   -31.916 6.932   1.00 34.37  ? 37  ARG B C   1 
ATOM   2526  O  O   . ARG B 1 37  ? 8.849   -30.978 6.389   1.00 32.18  ? 37  ARG B O   1 
ATOM   2527  C  CB  . ARG B 1 37  ? 8.565   -34.190 5.978   1.00 39.83  ? 37  ARG B CB  1 
ATOM   2528  C  CG  . ARG B 1 37  ? 9.597   -35.192 5.489   1.00 53.71  ? 37  ARG B CG  1 
ATOM   2529  C  CD  . ARG B 1 37  ? 9.442   -35.622 3.990   1.00 50.67  ? 37  ARG B CD  1 
ATOM   2530  N  NE  . ARG B 1 37  ? 9.349   -37.084 4.092   1.00 47.00  ? 37  ARG B NE  1 
ATOM   2531  N  N   . ASP B 1 38  ? 6.966   -31.849 7.296   1.00 34.37  ? 38  ASP B N   1 
ATOM   2532  C  CA  . ASP B 1 38  ? 6.208   -30.611 7.144   1.00 37.24  ? 38  ASP B CA  1 
ATOM   2533  C  C   . ASP B 1 38  ? 6.798   -29.482 7.983   1.00 36.25  ? 38  ASP B C   1 
ATOM   2534  O  O   . ASP B 1 38  ? 6.923   -28.350 7.501   1.00 37.77  ? 38  ASP B O   1 
ATOM   2535  C  CB  . ASP B 1 38  ? 4.806   -30.675 7.724   1.00 56.25  ? 38  ASP B CB  1 
ATOM   2536  C  CG  . ASP B 1 38  ? 3.725   -30.820 6.680   1.00 68.69  ? 38  ASP B CG  1 
ATOM   2537  O  OD1 . ASP B 1 38  ? 3.675   -31.909 6.107   1.00 66.95  ? 38  ASP B OD1 1 
ATOM   2538  O  OD2 . ASP B 1 38  ? 3.035   -29.801 6.410   1.00 75.38  ? 38  ASP B OD2 1 
ATOM   2539  N  N   . LEU B 1 39  ? 7.135   -29.801 9.240   1.00 30.11  ? 39  LEU B N   1 
ATOM   2540  C  CA  . LEU B 1 39  ? 7.793   -28.838 10.109  1.00 32.25  ? 39  LEU B CA  1 
ATOM   2541  C  C   . LEU B 1 39  ? 9.143   -28.379 9.529   1.00 30.52  ? 39  LEU B C   1 
ATOM   2542  O  O   . LEU B 1 39  ? 9.419   -27.199 9.531   1.00 31.56  ? 39  LEU B O   1 
ATOM   2543  C  CB  . LEU B 1 39  ? 7.869   -29.449 11.508  1.00 35.21  ? 39  LEU B CB  1 
ATOM   2544  C  CG  . LEU B 1 39  ? 8.440   -28.614 12.652  1.00 32.94  ? 39  LEU B CG  1 
ATOM   2545  C  CD1 . LEU B 1 39  ? 9.954   -28.633 12.610  1.00 34.01  ? 39  LEU B CD1 1 
ATOM   2546  C  CD2 . LEU B 1 39  ? 7.865   -27.190 12.614  1.00 38.05  ? 39  LEU B CD2 1 
ATOM   2547  N  N   . LEU B 1 40  ? 9.971   -29.267 8.998   1.00 28.40  ? 40  LEU B N   1 
ATOM   2548  C  CA  . LEU B 1 40  ? 11.264  -28.842 8.519   1.00 30.50  ? 40  LEU B CA  1 
ATOM   2549  C  C   . LEU B 1 40  ? 11.108  -27.806 7.431   1.00 31.63  ? 40  LEU B C   1 
ATOM   2550  O  O   . LEU B 1 40  ? 11.924  -26.899 7.295   1.00 31.52  ? 40  LEU B O   1 
ATOM   2551  C  CB  . LEU B 1 40  ? 12.076  -30.027 8.008   1.00 35.55  ? 40  LEU B CB  1 
ATOM   2552  C  CG  . LEU B 1 40  ? 12.508  -30.981 9.125   1.00 46.74  ? 40  LEU B CG  1 
ATOM   2553  C  CD1 . LEU B 1 40  ? 13.342  -32.071 8.469   1.00 51.55  ? 40  LEU B CD1 1 
ATOM   2554  C  CD2 . LEU B 1 40  ? 13.285  -30.313 10.272  1.00 44.97  ? 40  LEU B CD2 1 
ATOM   2555  N  N   . SER B 1 41  ? 10.060  -27.951 6.632   1.00 35.09  ? 41  SER B N   1 
ATOM   2556  C  CA  . SER B 1 41  ? 9.910   -27.061 5.496   1.00 38.29  ? 41  SER B CA  1 
ATOM   2557  C  C   . SER B 1 41  ? 9.416   -25.708 5.976   1.00 33.83  ? 41  SER B C   1 
ATOM   2558  O  O   . SER B 1 41  ? 9.458   -24.766 5.248   1.00 32.18  ? 41  SER B O   1 
ATOM   2559  C  CB  . SER B 1 41  ? 8.987   -27.630 4.425   1.00 42.29  ? 41  SER B CB  1 
ATOM   2560  O  OG  . SER B 1 41  ? 7.661   -27.615 4.929   1.00 41.48  ? 41  SER B OG  1 
ATOM   2561  N  N   . ASP B 1 42  ? 8.959   -25.590 7.212   1.00 34.50  ? 42  ASP B N   1 
ATOM   2562  C  CA  . ASP B 1 42  ? 8.416   -24.326 7.670   1.00 34.48  ? 42  ASP B CA  1 
ATOM   2563  C  C   . ASP B 1 42  ? 9.275   -23.640 8.729   1.00 33.14  ? 42  ASP B C   1 
ATOM   2564  O  O   . ASP B 1 42  ? 8.944   -22.559 9.163   1.00 30.16  ? 42  ASP B O   1 
ATOM   2565  C  CB  . ASP B 1 42  ? 7.048   -24.573 8.286   1.00 38.81  ? 42  ASP B CB  1 
ATOM   2566  C  CG  . ASP B 1 42  ? 5.882   -24.632 7.326   1.00 37.95  ? 42  ASP B CG  1 
ATOM   2567  O  OD1 . ASP B 1 42  ? 6.007   -24.149 6.199   1.00 44.96  ? 42  ASP B OD1 1 
ATOM   2568  O  OD2 . ASP B 1 42  ? 4.857   -25.135 7.769   1.00 44.49  ? 42  ASP B OD2 1 
ATOM   2569  N  N   . VAL B 1 43  ? 10.319  -24.287 9.236   1.00 36.47  ? 43  VAL B N   1 
ATOM   2570  C  CA  . VAL B 1 43  ? 10.971  -23.803 10.444  1.00 34.95  ? 43  VAL B CA  1 
ATOM   2571  C  C   . VAL B 1 43  ? 11.631  -22.448 10.170  1.00 32.17  ? 43  VAL B C   1 
ATOM   2572  O  O   . VAL B 1 43  ? 11.622  -21.612 11.027  1.00 31.60  ? 43  VAL B O   1 
ATOM   2573  C  CB  . VAL B 1 43  ? 12.014  -24.825 10.918  1.00 38.41  ? 43  VAL B CB  1 
ATOM   2574  C  CG1 . VAL B 1 43  ? 13.232  -24.845 9.966   1.00 37.93  ? 43  VAL B CG1 1 
ATOM   2575  C  CG2 . VAL B 1 43  ? 12.387  -24.546 12.356  1.00 40.31  ? 43  VAL B CG2 1 
ATOM   2576  N  N   . ALA B 1 44  ? 12.155  -22.173 8.965   1.00 29.98  ? 44  ALA B N   1 
ATOM   2577  C  CA  . ALA B 1 44  ? 12.654  -20.840 8.649   1.00 29.11  ? 44  ALA B CA  1 
ATOM   2578  C  C   . ALA B 1 44  ? 11.568  -19.766 8.809   1.00 28.69  ? 44  ALA B C   1 
ATOM   2579  O  O   . ALA B 1 44  ? 11.846  -18.641 9.247   1.00 26.33  ? 44  ALA B O   1 
ATOM   2580  C  CB  . ALA B 1 44  ? 13.139  -20.828 7.217   1.00 31.65  ? 44  ALA B CB  1 
ATOM   2581  N  N   . SER B 1 45  ? 10.318  -20.108 8.442   1.00 27.57  ? 45  SER B N   1 
ATOM   2582  C  CA  . SER B 1 45  ? 9.310   -19.064 8.445   1.00 32.79  ? 45  SER B CA  1 
ATOM   2583  C  C   . SER B 1 45  ? 8.794   -18.879 9.872   1.00 29.14  ? 45  SER B C   1 
ATOM   2584  O  O   . SER B 1 45  ? 8.433   -17.768 10.225  1.00 28.15  ? 45  SER B O   1 
ATOM   2585  C  CB  . SER B 1 45  ? 8.247   -19.250 7.388   1.00 28.41  ? 45  SER B CB  1 
ATOM   2586  O  OG  . SER B 1 45  ? 7.591   -20.432 7.710   1.00 36.05  ? 45  SER B OG  1 
ATOM   2587  N  N   . LEU B 1 46  ? 8.914   -19.906 10.719  1.00 25.84  ? 46  LEU B N   1 
ATOM   2588  C  CA  . LEU B 1 46  ? 8.631   -19.753 12.122  1.00 23.99  ? 46  LEU B CA  1 
ATOM   2589  C  C   . LEU B 1 46  ? 9.679   -18.856 12.764  1.00 28.62  ? 46  LEU B C   1 
ATOM   2590  O  O   . LEU B 1 46  ? 9.357   -18.006 13.624  1.00 27.61  ? 46  LEU B O   1 
ATOM   2591  C  CB  . LEU B 1 46  ? 8.563   -21.130 12.769  1.00 24.30  ? 46  LEU B CB  1 
ATOM   2592  C  CG  . LEU B 1 46  ? 7.365   -21.961 12.310  1.00 27.12  ? 46  LEU B CG  1 
ATOM   2593  C  CD1 . LEU B 1 46  ? 7.404   -23.337 12.950  1.00 31.49  ? 46  LEU B CD1 1 
ATOM   2594  C  CD2 . LEU B 1 46  ? 6.029   -21.267 12.617  1.00 27.81  ? 46  LEU B CD2 1 
ATOM   2595  N  N   . GLU B 1 47  ? 10.948  -19.059 12.379  1.00 28.07  ? 47  GLU B N   1 
ATOM   2596  C  CA  . GLU B 1 47  ? 12.049  -18.281 12.919  1.00 27.29  ? 47  GLU B CA  1 
ATOM   2597  C  C   . GLU B 1 47  ? 11.748  -16.805 12.644  1.00 26.08  ? 47  GLU B C   1 
ATOM   2598  O  O   . GLU B 1 47  ? 11.789  -16.009 13.578  1.00 26.13  ? 47  GLU B O   1 
ATOM   2599  C  CB  . GLU B 1 47  ? 13.326  -18.828 12.302  1.00 29.47  ? 47  GLU B CB  1 
ATOM   2600  C  CG  . GLU B 1 47  ? 14.540  -17.980 12.636  1.00 38.85  ? 47  GLU B CG  1 
ATOM   2601  C  CD  . GLU B 1 47  ? 15.764  -18.250 11.822  1.00 41.27  ? 47  GLU B CD  1 
ATOM   2602  O  OE1 . GLU B 1 47  ? 16.488  -19.255 11.906  1.00 39.49  ? 47  GLU B OE1 1 
ATOM   2603  O  OE2 . GLU B 1 47  ? 15.906  -17.296 11.071  1.00 56.76  ? 47  GLU B OE2 1 
ATOM   2604  N  N   . ARG B 1 48  ? 11.348  -16.458 11.408  1.00 23.67  ? 48  ARG B N   1 
ATOM   2605  C  CA  . ARG B 1 48  ? 11.004  -15.075 11.107  1.00 26.33  ? 48  ARG B CA  1 
ATOM   2606  C  C   . ARG B 1 48  ? 9.752   -14.589 11.835  1.00 24.43  ? 48  ARG B C   1 
ATOM   2607  O  O   . ARG B 1 48  ? 9.716   -13.484 12.312  1.00 22.40  ? 48  ARG B O   1 
ATOM   2608  C  CB  . ARG B 1 48  ? 10.762  -14.858 9.610   1.00 29.02  ? 48  ARG B CB  1 
ATOM   2609  C  CG  . ARG B 1 48  ? 12.092  -14.974 8.905   1.00 31.04  ? 48  ARG B CG  1 
ATOM   2610  C  CD  . ARG B 1 48  ? 12.001  -14.386 7.522   1.00 36.27  ? 48  ARG B CD  1 
ATOM   2611  N  NE  . ARG B 1 48  ? 11.117  -15.169 6.661   1.00 34.91  ? 48  ARG B NE  1 
ATOM   2612  C  CZ  . ARG B 1 48  ? 11.337  -16.397 6.123   1.00 42.01  ? 48  ARG B CZ  1 
ATOM   2613  N  NH1 . ARG B 1 48  ? 12.499  -17.044 6.178   1.00 45.21  ? 48  ARG B NH1 1 
ATOM   2614  N  NH2 . ARG B 1 48  ? 10.352  -17.033 5.522   1.00 39.96  ? 48  ARG B NH2 1 
ATOM   2615  N  N   . ALA B 1 49  ? 8.702   -15.394 11.911  1.00 25.66  ? 49  ALA B N   1 
ATOM   2616  C  CA  . ALA B 1 49  ? 7.489   -14.997 12.604  1.00 24.75  ? 49  ALA B CA  1 
ATOM   2617  C  C   . ALA B 1 49  ? 7.752   -14.552 14.034  1.00 23.47  ? 49  ALA B C   1 
ATOM   2618  O  O   . ALA B 1 49  ? 7.350   -13.444 14.426  1.00 23.29  ? 49  ALA B O   1 
ATOM   2619  C  CB  . ALA B 1 49  ? 6.571   -16.152 12.589  1.00 23.88  ? 49  ALA B CB  1 
ATOM   2620  N  N   . VAL B 1 50  ? 8.476   -15.405 14.788  1.00 23.24  ? 50  VAL B N   1 
ATOM   2621  C  CA  . VAL B 1 50  ? 8.776   -15.104 16.170  1.00 22.88  ? 50  VAL B CA  1 
ATOM   2622  C  C   . VAL B 1 50  ? 9.801   -13.990 16.279  1.00 25.55  ? 50  VAL B C   1 
ATOM   2623  O  O   . VAL B 1 50  ? 9.722   -13.183 17.176  1.00 30.06  ? 50  VAL B O   1 
ATOM   2624  C  CB  . VAL B 1 50  ? 9.281   -16.316 16.954  1.00 29.53  ? 50  VAL B CB  1 
ATOM   2625  C  CG1 . VAL B 1 50  ? 9.674   -15.973 18.388  1.00 31.81  ? 50  VAL B CG1 1 
ATOM   2626  C  CG2 . VAL B 1 50  ? 8.232   -17.412 16.969  1.00 33.67  ? 50  VAL B CG2 1 
ATOM   2627  N  N   . GLY B 1 51  ? 10.746  -13.915 15.364  1.00 26.34  ? 51  GLY B N   1 
ATOM   2628  C  CA  . GLY B 1 51  ? 11.917  -13.093 15.561  1.00 24.82  ? 51  GLY B CA  1 
ATOM   2629  C  C   . GLY B 1 51  ? 11.859  -11.738 14.902  1.00 25.84  ? 51  GLY B C   1 
ATOM   2630  O  O   . GLY B 1 51  ? 12.440  -10.793 15.435  1.00 24.57  ? 51  GLY B O   1 
ATOM   2631  N  N   . PHE B 1 52  ? 11.139  -11.597 13.796  1.00 27.44  ? 52  PHE B N   1 
ATOM   2632  C  CA  . PHE B 1 52  ? 11.182  -10.333 13.071  1.00 28.83  ? 52  PHE B CA  1 
ATOM   2633  C  C   . PHE B 1 52  ? 10.704  -9.159  13.949  1.00 31.60  ? 52  PHE B C   1 
ATOM   2634  O  O   . PHE B 1 52  ? 11.352  -8.107  13.977  1.00 31.51  ? 52  PHE B O   1 
ATOM   2635  C  CB  . PHE B 1 52  ? 10.420  -10.409 11.760  1.00 30.51  ? 52  PHE B CB  1 
ATOM   2636  C  CG  . PHE B 1 52  ? 10.400  -9.072  11.069  1.00 30.39  ? 52  PHE B CG  1 
ATOM   2637  C  CD1 . PHE B 1 52  ? 11.504  -8.653  10.359  1.00 30.07  ? 52  PHE B CD1 1 
ATOM   2638  C  CD2 . PHE B 1 52  ? 9.340   -8.190  11.249  1.00 32.54  ? 52  PHE B CD2 1 
ATOM   2639  C  CE1 . PHE B 1 52  ? 11.481  -7.414  9.747   1.00 35.48  ? 52  PHE B CE1 1 
ATOM   2640  C  CE2 . PHE B 1 52  ? 9.348   -6.932  10.660  1.00 33.79  ? 52  PHE B CE2 1 
ATOM   2641  C  CZ  . PHE B 1 52  ? 10.382  -6.570  9.857   1.00 34.06  ? 52  PHE B CZ  1 
ATOM   2642  N  N   . ARG B 1 53  ? 9.645   -9.323  14.742  1.00 30.95  ? 53  ARG B N   1 
ATOM   2643  C  CA  . ARG B 1 53  ? 9.113   -8.167  15.436  1.00 29.07  ? 53  ARG B CA  1 
ATOM   2644  C  C   . ARG B 1 53  ? 10.030  -7.719  16.574  1.00 29.75  ? 53  ARG B C   1 
ATOM   2645  O  O   . ARG B 1 53  ? 9.791   -6.660  17.189  1.00 29.60  ? 53  ARG B O   1 
ATOM   2646  C  CB  . ARG B 1 53  ? 7.682   -8.433  15.905  1.00 34.44  ? 53  ARG B CB  1 
ATOM   2647  C  CG  . ARG B 1 53  ? 7.446   -9.568  16.881  1.00 36.67  ? 53  ARG B CG  1 
ATOM   2648  C  CD  . ARG B 1 53  ? 6.122   -9.489  17.664  1.00 44.76  ? 53  ARG B CD  1 
ATOM   2649  N  NE  . ARG B 1 53  ? 5.878   -10.793 18.289  1.00 46.74  ? 53  ARG B NE  1 
ATOM   2650  C  CZ  . ARG B 1 53  ? 5.881   -11.885 17.536  1.00 53.63  ? 53  ARG B CZ  1 
ATOM   2651  N  NH1 . ARG B 1 53  ? 5.986   -11.729 16.223  1.00 62.80  ? 53  ARG B NH1 1 
ATOM   2652  N  NH2 . ARG B 1 53  ? 5.734   -13.088 18.060  1.00 55.37  ? 53  ARG B NH2 1 
ATOM   2653  N  N   . ALA B 1 54  ? 11.025  -8.554  16.923  1.00 29.24  ? 54  ALA B N   1 
ATOM   2654  C  CA  . ALA B 1 54  ? 11.942  -8.244  18.020  1.00 31.68  ? 54  ALA B CA  1 
ATOM   2655  C  C   . ALA B 1 54  ? 13.254  -7.669  17.519  1.00 32.11  ? 54  ALA B C   1 
ATOM   2656  O  O   . ALA B 1 54  ? 14.144  -7.557  18.360  1.00 34.73  ? 54  ALA B O   1 
ATOM   2657  C  CB  . ALA B 1 54  ? 12.222  -9.470  18.871  1.00 31.07  ? 54  ALA B CB  1 
ATOM   2658  N  N   . GLN B 1 55  ? 13.341  -7.321  16.209  1.00 42.29  ? 55  GLN B N   1 
ATOM   2659  C  CA  . GLN B 1 55  ? 14.494  -6.679  15.596  1.00 52.72  ? 55  GLN B CA  1 
ATOM   2660  C  C   . GLN B 1 55  ? 14.733  -5.286  16.186  1.00 58.40  ? 55  GLN B C   1 
ATOM   2661  O  O   . GLN B 1 55  ? 13.768  -4.635  16.597  1.00 50.62  ? 55  GLN B O   1 
ATOM   2662  C  CB  . GLN B 1 55  ? 14.391  -6.468  14.087  1.00 56.99  ? 55  GLN B CB  1 
ATOM   2663  C  CG  . GLN B 1 55  ? 14.601  -7.704  13.212  1.00 64.22  ? 55  GLN B CG  1 
ATOM   2664  C  CD  . GLN B 1 55  ? 15.707  -8.686  13.576  1.00 64.48  ? 55  GLN B CD  1 
ATOM   2665  O  OE1 . GLN B 1 55  ? 16.310  -8.731  14.662  1.00 71.69  ? 55  GLN B OE1 1 
ATOM   2666  N  NE2 . GLN B 1 55  ? 15.913  -9.590  12.633  1.00 67.83  ? 55  GLN B NE2 1 
ATOM   2667  N  N   . PRO B 1 56  ? 16.018  -4.817  16.274  1.00 74.15  ? 56  PRO B N   1 
ATOM   2668  C  CA  . PRO B 1 56  ? 17.209  -5.615  15.880  1.00 70.13  ? 56  PRO B CA  1 
ATOM   2669  C  C   . PRO B 1 56  ? 17.965  -6.331  17.021  1.00 55.14  ? 56  PRO B C   1 
ATOM   2670  O  O   . PRO B 1 56  ? 18.753  -7.236  16.783  1.00 54.93  ? 56  PRO B O   1 
ATOM   2671  C  CB  . PRO B 1 56  ? 18.056  -4.555  15.139  1.00 68.80  ? 56  PRO B CB  1 
ATOM   2672  C  CG  . PRO B 1 56  ? 17.565  -3.209  15.715  1.00 76.58  ? 56  PRO B CG  1 
ATOM   2673  C  CD  . PRO B 1 56  ? 16.402  -3.466  16.720  1.00 69.22  ? 56  PRO B CD  1 
ATOM   2674  N  N   . ASP B 1 57  ? 17.553  -6.060  18.263  1.00 51.95  ? 57  ASP B N   1 
ATOM   2675  C  CA  . ASP B 1 57  ? 18.110  -6.617  19.484  1.00 52.60  ? 57  ASP B CA  1 
ATOM   2676  C  C   . ASP B 1 57  ? 17.937  -8.124  19.614  1.00 44.87  ? 57  ASP B C   1 
ATOM   2677  O  O   . ASP B 1 57  ? 18.707  -8.734  20.334  1.00 42.70  ? 57  ASP B O   1 
ATOM   2678  C  CB  . ASP B 1 57  ? 17.389  -6.057  20.706  1.00 60.22  ? 57  ASP B CB  1 
ATOM   2679  C  CG  . ASP B 1 57  ? 17.501  -4.538  20.855  1.00 73.16  ? 57  ASP B CG  1 
ATOM   2680  O  OD1 . ASP B 1 57  ? 18.426  -3.923  20.225  1.00 56.85  ? 57  ASP B OD1 1 
ATOM   2681  O  OD2 . ASP B 1 57  ? 16.649  -3.966  21.576  1.00 71.49  ? 57  ASP B OD2 1 
ATOM   2682  N  N   . GLY B 1 58  ? 16.899  -8.735  19.032  1.00 35.41  ? 58  GLY B N   1 
ATOM   2683  C  CA  . GLY B 1 58  ? 16.482  -10.054 19.471  1.00 32.03  ? 58  GLY B CA  1 
ATOM   2684  C  C   . GLY B 1 58  ? 17.503  -11.118 19.075  1.00 31.82  ? 58  GLY B C   1 
ATOM   2685  O  O   . GLY B 1 58  ? 17.798  -12.038 19.828  1.00 28.91  ? 58  GLY B O   1 
ATOM   2686  N  N   . ARG B 1 59  ? 18.047  -10.984 17.873  1.00 34.74  ? 59  ARG B N   1 
ATOM   2687  C  CA  . ARG B 1 59  ? 19.086  -11.876 17.364  1.00 36.38  ? 59  ARG B CA  1 
ATOM   2688  C  C   . ARG B 1 59  ? 18.680  -13.337 17.452  1.00 31.05  ? 59  ARG B C   1 
ATOM   2689  O  O   . ARG B 1 59  ? 19.518  -14.177 17.734  1.00 35.51  ? 59  ARG B O   1 
ATOM   2690  C  CB  . ARG B 1 59  ? 20.435  -11.556 18.016  1.00 41.96  ? 59  ARG B CB  1 
ATOM   2691  C  CG  . ARG B 1 59  ? 20.801  -10.215 17.383  1.00 52.79  ? 59  ARG B CG  1 
ATOM   2692  C  CD  . ARG B 1 59  ? 22.202  -9.718  17.175  1.00 69.53  ? 59  ARG B CD  1 
ATOM   2693  N  NE  . ARG B 1 59  ? 22.492  -8.923  18.374  1.00 84.95  ? 59  ARG B NE  1 
ATOM   2694  C  CZ  . ARG B 1 59  ? 22.825  -9.425  19.557  1.00 78.48  ? 59  ARG B CZ  1 
ATOM   2695  N  NH1 . ARG B 1 59  ? 23.397  -10.615 19.639  1.00 87.19  ? 59  ARG B NH1 1 
ATOM   2696  N  NH2 . ARG B 1 59  ? 22.647  -8.697  20.640  1.00 65.03  ? 59  ARG B NH2 1 
ATOM   2697  N  N   . LEU B 1 60  ? 17.410  -13.617 17.159  1.00 28.05  ? 60  LEU B N   1 
ATOM   2698  C  CA  . LEU B 1 60  ? 16.851  -14.964 17.245  1.00 28.24  ? 60  LEU B CA  1 
ATOM   2699  C  C   . LEU B 1 60  ? 17.253  -15.784 16.032  1.00 26.13  ? 60  LEU B C   1 
ATOM   2700  O  O   . LEU B 1 60  ? 17.082  -15.315 14.948  1.00 24.91  ? 60  LEU B O   1 
ATOM   2701  C  CB  . LEU B 1 60  ? 15.330  -14.919 17.370  1.00 23.47  ? 60  LEU B CB  1 
ATOM   2702  C  CG  . LEU B 1 60  ? 14.675  -16.284 17.367  1.00 25.38  ? 60  LEU B CG  1 
ATOM   2703  C  CD1 . LEU B 1 60  ? 14.960  -17.145 18.613  1.00 27.94  ? 60  LEU B CD1 1 
ATOM   2704  C  CD2 . LEU B 1 60  ? 13.212  -16.020 17.156  1.00 27.51  ? 60  LEU B CD2 1 
ATOM   2705  N  N   . SER B 1 61  ? 17.759  -17.001 16.218  1.00 27.72  ? 61  SER B N   1 
ATOM   2706  C  CA  . SER B 1 61  ? 17.991  -17.922 15.107  1.00 30.67  ? 61  SER B CA  1 
ATOM   2707  C  C   . SER B 1 61  ? 17.757  -19.336 15.593  1.00 28.38  ? 61  SER B C   1 
ATOM   2708  O  O   . SER B 1 61  ? 17.861  -19.613 16.781  1.00 30.88  ? 61  SER B O   1 
ATOM   2709  C  CB  . SER B 1 61  ? 19.394  -17.842 14.531  1.00 29.98  ? 61  SER B CB  1 
ATOM   2710  O  OG  . SER B 1 61  ? 20.385  -18.217 15.484  1.00 29.66  ? 61  SER B OG  1 
ATOM   2711  N  N   . CYS B 1 62  ? 17.483  -20.224 14.647  1.00 25.54  ? 62  CYS B N   1 
ATOM   2712  C  CA  . CYS B 1 62  ? 17.306  -21.623 14.936  1.00 23.76  ? 62  CYS B CA  1 
ATOM   2713  C  C   . CYS B 1 62  ? 18.154  -22.415 13.954  1.00 25.51  ? 62  CYS B C   1 
ATOM   2714  O  O   . CYS B 1 62  ? 18.067  -22.194 12.771  1.00 25.73  ? 62  CYS B O   1 
ATOM   2715  C  CB  . CYS B 1 62  ? 15.862  -22.007 14.771  1.00 24.45  ? 62  CYS B CB  1 
ATOM   2716  S  SG  . CYS B 1 62  ? 15.663  -23.759 15.134  1.00 30.30  ? 62  CYS B SG  1 
ATOM   2717  N  N   . VAL B 1 63  ? 19.051  -23.263 14.419  1.00 23.54  ? 63  VAL B N   1 
ATOM   2718  C  CA  . VAL B 1 63  ? 19.706  -24.169 13.498  1.00 25.71  ? 63  VAL B CA  1 
ATOM   2719  C  C   . VAL B 1 63  ? 19.142  -25.586 13.737  1.00 26.26  ? 63  VAL B C   1 
ATOM   2720  O  O   . VAL B 1 63  ? 19.028  -26.052 14.858  1.00 27.55  ? 63  VAL B O   1 
ATOM   2721  C  CB  . VAL B 1 63  ? 21.221  -24.102 13.665  1.00 26.58  ? 63  VAL B CB  1 
ATOM   2722  C  CG1 . VAL B 1 63  ? 21.929  -25.134 12.806  1.00 27.71  ? 63  VAL B CG1 1 
ATOM   2723  C  CG2 . VAL B 1 63  ? 21.762  -22.697 13.430  1.00 28.32  ? 63  VAL B CG2 1 
ATOM   2724  N  N   . THR B 1 64  ? 18.746  -26.247 12.653  1.00 23.17  ? 64  THR B N   1 
ATOM   2725  C  CA  . THR B 1 64  ? 18.096  -27.527 12.697  1.00 26.99  ? 64  THR B CA  1 
ATOM   2726  C  C   . THR B 1 64  ? 19.056  -28.587 12.168  1.00 29.57  ? 64  THR B C   1 
ATOM   2727  O  O   . THR B 1 64  ? 19.640  -28.442 11.099  1.00 28.06  ? 64  THR B O   1 
ATOM   2728  C  CB  . THR B 1 64  ? 16.841  -27.502 11.851  1.00 28.40  ? 64  THR B CB  1 
ATOM   2729  O  OG1 . THR B 1 64  ? 16.045  -26.451 12.394  1.00 29.92  ? 64  THR B OG1 1 
ATOM   2730  C  CG2 . THR B 1 64  ? 16.117  -28.827 12.016  1.00 34.19  ? 64  THR B CG2 1 
ATOM   2731  N  N   . GLY B 1 65  ? 19.175  -29.680 12.921  1.00 27.69  ? 65  GLY B N   1 
ATOM   2732  C  CA  . GLY B 1 65  ? 20.046  -30.750 12.523  1.00 27.67  ? 65  GLY B CA  1 
ATOM   2733  C  C   . GLY B 1 65  ? 19.345  -32.096 12.601  1.00 29.96  ? 65  GLY B C   1 
ATOM   2734  O  O   . GLY B 1 65  ? 18.437  -32.286 13.401  1.00 27.43  ? 65  GLY B O   1 
ATOM   2735  N  N   . ILE B 1 66  ? 19.859  -33.025 11.770  1.00 36.72  ? 66  ILE B N   1 
ATOM   2736  C  CA  . ILE B 1 66  ? 19.248  -34.329 11.546  1.00 31.28  ? 66  ILE B CA  1 
ATOM   2737  C  C   . ILE B 1 66  ? 20.333  -35.382 11.693  1.00 28.58  ? 66  ILE B C   1 
ATOM   2738  O  O   . ILE B 1 66  ? 21.434  -35.237 11.173  1.00 24.71  ? 66  ILE B O   1 
ATOM   2739  C  CB  . ILE B 1 66  ? 18.621  -34.339 10.149  1.00 31.46  ? 66  ILE B CB  1 
ATOM   2740  C  CG1 . ILE B 1 66  ? 17.541  -33.249 10.018  1.00 28.95  ? 66  ILE B CG1 1 
ATOM   2741  C  CG2 . ILE B 1 66  ? 18.121  -35.737 9.796   1.00 30.91  ? 66  ILE B CG2 1 
ATOM   2742  C  CD1 . ILE B 1 66  ? 17.390  -32.815 8.597   1.00 31.16  ? 66  ILE B CD1 1 
ATOM   2743  N  N   . GLY B 1 67  ? 20.015  -36.420 12.451  1.00 30.79  ? 67  GLY B N   1 
ATOM   2744  C  CA  . GLY B 1 67  ? 20.972  -37.490 12.720  1.00 32.07  ? 67  GLY B CA  1 
ATOM   2745  C  C   . GLY B 1 67  ? 20.976  -38.544 11.604  1.00 35.09  ? 67  GLY B C   1 
ATOM   2746  O  O   . GLY B 1 67  ? 20.070  -38.604 10.768  1.00 35.53  ? 67  GLY B O   1 
ATOM   2747  N  N   . SER B 1 68  ? 21.995  -39.404 11.649  1.00 33.97  ? 68  SER B N   1 
ATOM   2748  C  CA  . SER B 1 68  ? 22.231  -40.452 10.655  1.00 36.97  ? 68  SER B CA  1 
ATOM   2749  C  C   . SER B 1 68  ? 21.031  -41.413 10.470  1.00 33.74  ? 68  SER B C   1 
ATOM   2750  O  O   . SER B 1 68  ? 20.549  -41.585 9.376   1.00 31.21  ? 68  SER B O   1 
ATOM   2751  C  CB  . SER B 1 68  ? 23.462  -41.185 11.088  1.00 35.55  ? 68  SER B CB  1 
ATOM   2752  O  OG  . SER B 1 68  ? 23.947  -42.007 10.060  1.00 36.49  ? 68  SER B OG  1 
ATOM   2753  N  N   . GLU B 1 69  ? 20.519  -42.031 11.530  1.00 30.68  ? 69  GLU B N   1 
ATOM   2754  C  CA  . GLU B 1 69  ? 19.436  -42.971 11.375  1.00 34.56  ? 69  GLU B CA  1 
ATOM   2755  C  C   . GLU B 1 69  ? 18.172  -42.279 10.911  1.00 35.13  ? 69  GLU B C   1 
ATOM   2756  O  O   . GLU B 1 69  ? 17.393  -42.846 10.144  1.00 34.63  ? 69  GLU B O   1 
ATOM   2757  C  CB  . GLU B 1 69  ? 19.062  -43.667 12.679  1.00 47.53  ? 69  GLU B CB  1 
ATOM   2758  C  CG  . GLU B 1 69  ? 19.822  -44.958 13.010  1.00 58.85  ? 69  GLU B CG  1 
ATOM   2759  C  CD  . GLU B 1 69  ? 19.340  -45.468 14.365  1.00 71.16  ? 69  GLU B CD  1 
ATOM   2760  O  OE1 . GLU B 1 69  ? 18.094  -45.587 14.632  1.00 83.11  ? 69  GLU B OE1 1 
ATOM   2761  O  OE2 . GLU B 1 69  ? 20.252  -45.703 15.188  1.00 72.09  ? 69  GLU B OE2 1 
ATOM   2762  N  N   . ALA B 1 70  ? 17.938  -41.064 11.403  1.00 37.67  ? 70  ALA B N   1 
ATOM   2763  C  CA  . ALA B 1 70  ? 16.746  -40.322 10.994  1.00 39.48  ? 70  ALA B CA  1 
ATOM   2764  C  C   . ALA B 1 70  ? 16.869  -39.869 9.540   1.00 33.81  ? 70  ALA B C   1 
ATOM   2765  O  O   . ALA B 1 70  ? 15.876  -39.811 8.829   1.00 28.80  ? 70  ALA B O   1 
ATOM   2766  C  CB  . ALA B 1 70  ? 16.555  -39.146 11.893  1.00 42.69  ? 70  ALA B CB  1 
ATOM   2767  N  N   . TRP B 1 71  ? 18.086  -39.549 9.088   1.00 34.52  ? 71  TRP B N   1 
ATOM   2768  C  CA  . TRP B 1 71  ? 18.247  -39.163 7.696   1.00 35.61  ? 71  TRP B CA  1 
ATOM   2769  C  C   . TRP B 1 71  ? 17.668  -40.218 6.743   1.00 44.54  ? 71  TRP B C   1 
ATOM   2770  O  O   . TRP B 1 71  ? 16.946  -39.859 5.803   1.00 41.56  ? 71  TRP B O   1 
ATOM   2771  C  CB  . TRP B 1 71  ? 19.721  -38.932 7.378   1.00 33.92  ? 71  TRP B CB  1 
ATOM   2772  C  CG  . TRP B 1 71  ? 19.868  -38.371 6.006   1.00 39.88  ? 71  TRP B CG  1 
ATOM   2773  C  CD1 . TRP B 1 71  ? 19.826  -39.057 4.825   1.00 46.29  ? 71  TRP B CD1 1 
ATOM   2774  C  CD2 . TRP B 1 71  ? 19.981  -36.974 5.670   1.00 40.41  ? 71  TRP B CD2 1 
ATOM   2775  N  NE1 . TRP B 1 71  ? 19.965  -38.174 3.782   1.00 45.90  ? 71  TRP B NE1 1 
ATOM   2776  C  CE2 . TRP B 1 71  ? 20.036  -36.889 4.268   1.00 41.22  ? 71  TRP B CE2 1 
ATOM   2777  C  CE3 . TRP B 1 71  ? 20.066  -35.805 6.410   1.00 39.24  ? 71  TRP B CE3 1 
ATOM   2778  C  CZ2 . TRP B 1 71  ? 20.179  -35.677 3.610   1.00 43.32  ? 71  TRP B CZ2 1 
ATOM   2779  C  CZ3 . TRP B 1 71  ? 20.214  -34.610 5.747   1.00 40.81  ? 71  TRP B CZ3 1 
ATOM   2780  C  CH2 . TRP B 1 71  ? 20.238  -34.539 4.371   1.00 43.40  ? 71  TRP B CH2 1 
ATOM   2781  N  N   . ASP B 1 72  ? 17.958  -41.509 7.036   1.00 52.25  ? 72  ASP B N   1 
ATOM   2782  C  CA  . ASP B 1 72  ? 17.471  -42.688 6.313   1.00 53.72  ? 72  ASP B CA  1 
ATOM   2783  C  C   . ASP B 1 72  ? 15.952  -42.814 6.384   1.00 47.33  ? 72  ASP B C   1 
ATOM   2784  O  O   . ASP B 1 72  ? 15.322  -43.220 5.440   1.00 55.81  ? 72  ASP B O   1 
ATOM   2785  C  CB  . ASP B 1 72  ? 18.190  -43.967 6.745   1.00 51.94  ? 72  ASP B CB  1 
ATOM   2786  C  CG  . ASP B 1 72  ? 19.678  -43.984 6.343   1.00 58.11  ? 72  ASP B CG  1 
ATOM   2787  O  OD1 . ASP B 1 72  ? 20.063  -43.266 5.335   1.00 42.02  ? 72  ASP B OD1 1 
ATOM   2788  O  OD2 . ASP B 1 72  ? 20.480  -44.660 7.067   1.00 52.26  ? 72  ASP B OD2 1 
ATOM   2789  N  N   . ARG B 1 73  ? 15.321  -42.462 7.489   1.00 44.03  ? 73  ARG B N   1 
ATOM   2790  C  CA  . ARG B 1 73  ? 13.873  -42.511 7.546   1.00 39.27  ? 73  ARG B CA  1 
ATOM   2791  C  C   . ARG B 1 73  ? 13.220  -41.356 6.768   1.00 44.81  ? 73  ARG B C   1 
ATOM   2792  O  O   . ARG B 1 73  ? 12.080  -41.436 6.390   1.00 44.90  ? 73  ARG B O   1 
ATOM   2793  C  CB  . ARG B 1 73  ? 13.399  -42.548 9.000   1.00 36.53  ? 73  ARG B CB  1 
ATOM   2794  C  CG  . ARG B 1 73  ? 14.058  -43.646 9.813   1.00 37.03  ? 73  ARG B CG  1 
ATOM   2795  C  CD  . ARG B 1 73  ? 13.776  -43.465 11.293  1.00 44.71  ? 73  ARG B CD  1 
ATOM   2796  N  NE  . ARG B 1 73  ? 12.353  -43.306 11.653  1.00 42.29  ? 73  ARG B NE  1 
ATOM   2797  C  CZ  . ARG B 1 73  ? 11.937  -42.948 12.873  1.00 47.23  ? 73  ARG B CZ  1 
ATOM   2798  N  NH1 . ARG B 1 73  ? 12.852  -42.540 13.752  1.00 61.38  ? 73  ARG B NH1 1 
ATOM   2799  N  NH2 . ARG B 1 73  ? 10.646  -42.921 13.205  1.00 42.81  ? 73  ARG B NH2 1 
ATOM   2800  N  N   . LEU B 1 74  ? 13.876  -40.237 6.551   1.00 46.27  ? 74  LEU B N   1 
ATOM   2801  C  CA  . LEU B 1 74  ? 13.139  -39.056 6.151   1.00 42.94  ? 74  LEU B CA  1 
ATOM   2802  C  C   . LEU B 1 74  ? 13.265  -38.808 4.664   1.00 43.95  ? 74  LEU B C   1 
ATOM   2803  O  O   . LEU B 1 74  ? 12.436  -38.087 4.091   1.00 39.76  ? 74  LEU B O   1 
ATOM   2804  C  CB  . LEU B 1 74  ? 13.706  -37.835 6.870   1.00 40.30  ? 74  LEU B CB  1 
ATOM   2805  C  CG  . LEU B 1 74  ? 13.324  -37.724 8.339   1.00 41.64  ? 74  LEU B CG  1 
ATOM   2806  C  CD1 . LEU B 1 74  ? 14.048  -36.471 8.844   1.00 44.99  ? 74  LEU B CD1 1 
ATOM   2807  C  CD2 . LEU B 1 74  ? 11.816  -37.666 8.547   1.00 40.87  ? 74  LEU B CD2 1 
ATOM   2808  N  N   . PHE B 1 75  ? 14.416  -39.224 4.131   1.00 47.70  ? 75  PHE B N   1 
ATOM   2809  C  CA  . PHE B 1 75  ? 14.878  -38.813 2.812   1.00 53.50  ? 75  PHE B CA  1 
ATOM   2810  C  C   . PHE B 1 75  ? 15.323  -40.060 2.066   1.00 57.00  ? 75  PHE B C   1 
ATOM   2811  O  O   . PHE B 1 75  ? 15.687  -41.024 2.696   1.00 57.76  ? 75  PHE B O   1 
ATOM   2812  C  CB  . PHE B 1 75  ? 16.089  -37.882 2.877   1.00 44.79  ? 75  PHE B CB  1 
ATOM   2813  C  CG  . PHE B 1 75  ? 15.843  -36.636 3.713   1.00 47.66  ? 75  PHE B CG  1 
ATOM   2814  C  CD1 . PHE B 1 75  ? 14.755  -35.808 3.476   1.00 42.38  ? 75  PHE B CD1 1 
ATOM   2815  C  CD2 . PHE B 1 75  ? 16.644  -36.348 4.798   1.00 47.56  ? 75  PHE B CD2 1 
ATOM   2816  C  CE1 . PHE B 1 75  ? 14.503  -34.705 4.290   1.00 43.50  ? 75  PHE B CE1 1 
ATOM   2817  C  CE2 . PHE B 1 75  ? 16.378  -35.264 5.618   1.00 50.38  ? 75  PHE B CE2 1 
ATOM   2818  C  CZ  . PHE B 1 75  ? 15.304  -34.443 5.364   1.00 45.82  ? 75  PHE B CZ  1 
ATOM   2819  N  N   . SER B 1 76  ? 15.311  -40.112 0.738   1.00 72.72  ? 76  SER B N   1 
ATOM   2820  C  CA  . SER B 1 76  ? 16.179  -41.110 0.124   1.00 74.93  ? 76  SER B CA  1 
ATOM   2821  C  C   . SER B 1 76  ? 17.032  -40.397 -0.916  1.00 71.12  ? 76  SER B C   1 
ATOM   2822  O  O   . SER B 1 76  ? 16.999  -39.173 -1.018  1.00 61.21  ? 76  SER B O   1 
ATOM   2823  C  CB  . SER B 1 76  ? 15.434  -42.341 -0.363  1.00 67.95  ? 76  SER B CB  1 
ATOM   2824  O  OG  . SER B 1 76  ? 14.331  -41.920 -1.130  1.00 72.00  ? 76  SER B OG  1 
ATOM   2825  N  N   . GLY B 1 77  ? 17.910  -41.129 -1.592  1.00 61.21  ? 77  GLY B N   1 
ATOM   2826  C  CA  . GLY B 1 77  ? 18.851  -40.429 -2.438  1.00 62.11  ? 77  GLY B CA  1 
ATOM   2827  C  C   . GLY B 1 77  ? 20.159  -40.258 -1.683  1.00 51.89  ? 77  GLY B C   1 
ATOM   2828  O  O   . GLY B 1 77  ? 20.519  -41.154 -0.937  1.00 46.85  ? 77  GLY B O   1 
ATOM   2829  N  N   . ALA B 1 78  ? 20.850  -39.133 -1.897  1.00 52.36  ? 78  ALA B N   1 
ATOM   2830  C  CA  . ALA B 1 78  ? 22.190  -38.957 -1.363  1.00 53.49  ? 78  ALA B CA  1 
ATOM   2831  C  C   . ALA B 1 78  ? 22.112  -38.681 0.149   1.00 52.96  ? 78  ALA B C   1 
ATOM   2832  O  O   . ALA B 1 78  ? 21.183  -38.049 0.637   1.00 48.62  ? 78  ALA B O   1 
ATOM   2833  C  CB  . ALA B 1 78  ? 22.944  -37.860 -2.130  1.00 45.75  ? 78  ALA B CB  1 
ATOM   2834  N  N   . ARG B 1 79  ? 23.108  -39.212 0.873   1.00 48.01  ? 79  ARG B N   1 
ATOM   2835  C  CA  . ARG B 1 79  ? 23.442  -38.889 2.243   1.00 39.89  ? 79  ARG B CA  1 
ATOM   2836  C  C   . ARG B 1 79  ? 24.645  -37.956 2.264   1.00 39.76  ? 79  ARG B C   1 
ATOM   2837  O  O   . ARG B 1 79  ? 25.558  -38.040 1.431   1.00 37.53  ? 79  ARG B O   1 
ATOM   2838  C  CB  . ARG B 1 79  ? 23.845  -40.130 3.039   1.00 38.65  ? 79  ARG B CB  1 
ATOM   2839  C  CG  . ARG B 1 79  ? 22.636  -41.032 3.216   1.00 39.69  ? 79  ARG B CG  1 
ATOM   2840  C  CD  . ARG B 1 79  ? 23.080  -42.277 3.894   1.00 48.20  ? 79  ARG B CD  1 
ATOM   2841  N  NE  . ARG B 1 79  ? 23.866  -41.855 5.055   1.00 57.62  ? 79  ARG B NE  1 
ATOM   2842  C  CZ  . ARG B 1 79  ? 23.443  -41.871 6.302   1.00 53.58  ? 79  ARG B CZ  1 
ATOM   2843  N  NH1 . ARG B 1 79  ? 22.270  -42.393 6.620   1.00 53.38  ? 79  ARG B NH1 1 
ATOM   2844  N  NH2 . ARG B 1 79  ? 24.243  -41.385 7.215   1.00 52.60  ? 79  ARG B NH2 1 
ATOM   2845  N  N   . PRO B 1 80  ? 24.717  -37.021 3.242   1.00 40.70  ? 80  PRO B N   1 
ATOM   2846  C  CA  . PRO B 1 80  ? 25.963  -36.303 3.484   1.00 35.72  ? 80  PRO B CA  1 
ATOM   2847  C  C   . PRO B 1 80  ? 27.070  -37.320 3.717   1.00 37.57  ? 80  PRO B C   1 
ATOM   2848  O  O   . PRO B 1 80  ? 26.908  -38.305 4.448   1.00 43.39  ? 80  PRO B O   1 
ATOM   2849  C  CB  . PRO B 1 80  ? 25.659  -35.459 4.718   1.00 39.81  ? 80  PRO B CB  1 
ATOM   2850  C  CG  . PRO B 1 80  ? 24.155  -35.301 4.641   1.00 48.59  ? 80  PRO B CG  1 
ATOM   2851  C  CD  . PRO B 1 80  ? 23.640  -36.652 4.180   1.00 43.38  ? 80  PRO B CD  1 
ATOM   2852  N  N   . ALA B 1 81  ? 28.217  -37.042 3.102   1.00 46.18  ? 81  ALA B N   1 
ATOM   2853  C  CA  . ALA B 1 81  ? 29.380  -37.914 3.153   1.00 40.41  ? 81  ALA B CA  1 
ATOM   2854  C  C   . ALA B 1 81  ? 29.786  -38.241 4.598   1.00 39.82  ? 81  ALA B C   1 
ATOM   2855  O  O   . ALA B 1 81  ? 30.268  -39.326 4.873   1.00 34.03  ? 81  ALA B O   1 
ATOM   2856  C  CB  . ALA B 1 81  ? 30.520  -37.190 2.413   1.00 37.10  ? 81  ALA B CB  1 
ATOM   2857  N  N   . GLY B 1 82  ? 29.671  -37.290 5.531   1.00 38.53  ? 82  GLY B N   1 
ATOM   2858  C  CA  . GLY B 1 82  ? 30.305  -37.442 6.841   1.00 34.34  ? 82  GLY B CA  1 
ATOM   2859  C  C   . GLY B 1 82  ? 29.320  -37.903 7.904   1.00 31.86  ? 82  GLY B C   1 
ATOM   2860  O  O   . GLY B 1 82  ? 29.686  -38.075 9.067   1.00 30.25  ? 82  GLY B O   1 
ATOM   2861  N  N   . LEU B 1 83  ? 28.059  -38.128 7.507   1.00 32.90  ? 83  LEU B N   1 
ATOM   2862  C  CA  . LEU B 1 83  ? 27.009  -38.352 8.486   1.00 36.31  ? 83  LEU B CA  1 
ATOM   2863  C  C   . LEU B 1 83  ? 27.010  -39.814 8.929   1.00 33.94  ? 83  LEU B C   1 
ATOM   2864  O  O   . LEU B 1 83  ? 26.792  -40.665 8.117   1.00 39.19  ? 83  LEU B O   1 
ATOM   2865  C  CB  . LEU B 1 83  ? 25.671  -37.911 7.892   1.00 36.59  ? 83  LEU B CB  1 
ATOM   2866  C  CG  . LEU B 1 83  ? 24.476  -38.059 8.828   1.00 38.01  ? 83  LEU B CG  1 
ATOM   2867  C  CD1 . LEU B 1 83  ? 24.698  -37.337 10.152  1.00 36.40  ? 83  LEU B CD1 1 
ATOM   2868  C  CD2 . LEU B 1 83  ? 23.193  -37.607 8.115   1.00 42.28  ? 83  LEU B CD2 1 
ATOM   2869  N  N   . HIS B 1 84  ? 27.242  -40.068 10.215  1.00 36.21  ? 84  HIS B N   1 
ATOM   2870  C  CA  . HIS B 1 84  ? 27.177  -41.364 10.887  1.00 33.28  ? 84  HIS B CA  1 
ATOM   2871  C  C   . HIS B 1 84  ? 26.795  -41.131 12.361  1.00 37.99  ? 84  HIS B C   1 
ATOM   2872  O  O   . HIS B 1 84  ? 26.761  -39.988 12.858  1.00 38.51  ? 84  HIS B O   1 
ATOM   2873  C  CB  . HIS B 1 84  ? 28.542  -42.036 10.812  1.00 31.31  ? 84  HIS B CB  1 
ATOM   2874  C  CG  . HIS B 1 84  ? 29.718  -41.188 11.107  1.00 29.73  ? 84  HIS B CG  1 
ATOM   2875  N  ND1 . HIS B 1 84  ? 30.509  -40.597 10.131  1.00 32.60  ? 84  HIS B ND1 1 
ATOM   2876  C  CD2 . HIS B 1 84  ? 30.252  -40.831 12.314  1.00 28.73  ? 84  HIS B CD2 1 
ATOM   2877  C  CE1 . HIS B 1 84  ? 31.523  -39.915 10.738  1.00 32.99  ? 84  HIS B CE1 1 
ATOM   2878  N  NE2 . HIS B 1 84  ? 31.386  -40.034 12.072  1.00 28.23  ? 84  HIS B NE2 1 
ATOM   2879  N  N   . PRO B 1 85  ? 26.425  -42.164 13.126  1.00 38.21  ? 85  PRO B N   1 
ATOM   2880  C  CA  . PRO B 1 85  ? 26.076  -41.981 14.544  1.00 30.84  ? 85  PRO B CA  1 
ATOM   2881  C  C   . PRO B 1 85  ? 27.333  -41.619 15.302  1.00 32.39  ? 85  PRO B C   1 
ATOM   2882  O  O   . PRO B 1 85  ? 28.420  -41.946 14.878  1.00 41.32  ? 85  PRO B O   1 
ATOM   2883  C  CB  . PRO B 1 85  ? 25.531  -43.337 14.960  1.00 32.62  ? 85  PRO B CB  1 
ATOM   2884  C  CG  . PRO B 1 85  ? 25.137  -43.951 13.628  1.00 34.15  ? 85  PRO B CG  1 
ATOM   2885  C  CD  . PRO B 1 85  ? 26.255  -43.550 12.673  1.00 37.21  ? 85  PRO B CD  1 
ATOM   2886  N  N   . PHE B 1 86  ? 27.171  -40.826 16.344  1.00 34.14  ? 86  PHE B N   1 
ATOM   2887  C  CA  . PHE B 1 86  ? 28.239  -40.465 17.257  1.00 32.90  ? 86  PHE B CA  1 
ATOM   2888  C  C   . PHE B 1 86  ? 28.913  -41.749 17.730  1.00 34.64  ? 86  PHE B C   1 
ATOM   2889  O  O   . PHE B 1 86  ? 28.208  -42.715 18.068  1.00 30.47  ? 86  PHE B O   1 
ATOM   2890  C  CB  . PHE B 1 86  ? 27.591  -39.735 18.448  1.00 31.45  ? 86  PHE B CB  1 
ATOM   2891  C  CG  . PHE B 1 86  ? 28.594  -39.217 19.437  1.00 30.46  ? 86  PHE B CG  1 
ATOM   2892  C  CD1 . PHE B 1 86  ? 29.225  -38.014 19.230  1.00 35.30  ? 86  PHE B CD1 1 
ATOM   2893  C  CD2 . PHE B 1 86  ? 28.934  -39.961 20.544  1.00 35.53  ? 86  PHE B CD2 1 
ATOM   2894  C  CE1 . PHE B 1 86  ? 30.117  -37.513 20.165  1.00 37.50  ? 86  PHE B CE1 1 
ATOM   2895  C  CE2 . PHE B 1 86  ? 29.855  -39.476 21.462  1.00 34.91  ? 86  PHE B CE2 1 
ATOM   2896  C  CZ  . PHE B 1 86  ? 30.448  -38.249 21.265  1.00 36.62  ? 86  PHE B CZ  1 
ATOM   2897  N  N   . ARG B 1 87  ? 30.251  -41.731 17.714  1.00 38.07  ? 87  ARG B N   1 
ATOM   2898  C  CA  . ARG B 1 87  ? 31.063  -42.879 18.111  1.00 41.51  ? 87  ARG B CA  1 
ATOM   2899  C  C   . ARG B 1 87  ? 31.477  -42.703 19.580  1.00 38.34  ? 87  ARG B C   1 
ATOM   2900  O  O   . ARG B 1 87  ? 32.214  -41.711 19.881  1.00 31.30  ? 87  ARG B O   1 
ATOM   2901  C  CB  . ARG B 1 87  ? 32.398  -42.987 17.353  1.00 46.14  ? 87  ARG B CB  1 
ATOM   2902  C  CG  . ARG B 1 87  ? 32.498  -42.994 15.829  1.00 49.84  ? 87  ARG B CG  1 
ATOM   2903  C  CD  . ARG B 1 87  ? 33.956  -42.945 15.246  1.00 43.94  ? 87  ARG B CD  1 
ATOM   2904  N  N   . GLU B 1 88  ? 31.003  -43.652 20.457  1.00 35.40  ? 88  GLU B N   1 
ATOM   2905  C  CA  . GLU B 1 88  ? 31.373  -43.737 21.860  1.00 33.34  ? 88  GLU B CA  1 
ATOM   2906  C  C   . GLU B 1 88  ? 32.902  -43.793 21.962  1.00 34.97  ? 88  GLU B C   1 
ATOM   2907  O  O   . GLU B 1 88  ? 33.559  -44.365 21.112  1.00 31.32  ? 88  GLU B O   1 
ATOM   2908  C  CB  . GLU B 1 88  ? 30.962  -45.048 22.508  1.00 36.56  ? 88  GLU B CB  1 
ATOM   2909  C  CG  . GLU B 1 88  ? 29.508  -45.118 22.922  1.00 50.19  ? 88  GLU B CG  1 
ATOM   2910  C  CD  . GLU B 1 88  ? 29.263  -45.843 24.263  1.00 67.57  ? 88  GLU B CD  1 
ATOM   2911  O  OE1 . GLU B 1 88  ? 29.952  -46.890 24.400  1.00 62.64  ? 88  GLU B OE1 1 
ATOM   2912  O  OE2 . GLU B 1 88  ? 28.434  -45.424 25.168  1.00 52.47  ? 88  GLU B OE2 1 
ATOM   2913  N  N   . LEU B 1 89  ? 33.496  -43.160 22.969  1.00 33.32  ? 89  LEU B N   1 
ATOM   2914  C  CA  . LEU B 1 89  ? 34.900  -43.342 23.265  1.00 33.13  ? 89  LEU B CA  1 
ATOM   2915  C  C   . LEU B 1 89  ? 35.000  -43.918 24.681  1.00 41.02  ? 89  LEU B C   1 
ATOM   2916  O  O   . LEU B 1 89  ? 34.519  -43.330 25.652  1.00 35.74  ? 89  LEU B O   1 
ATOM   2917  C  CB  . LEU B 1 89  ? 35.687  -42.059 23.128  1.00 32.82  ? 89  LEU B CB  1 
ATOM   2918  C  CG  . LEU B 1 89  ? 35.620  -41.385 21.760  1.00 37.73  ? 89  LEU B CG  1 
ATOM   2919  C  CD1 . LEU B 1 89  ? 36.269  -40.003 21.750  1.00 37.15  ? 89  LEU B CD1 1 
ATOM   2920  C  CD2 . LEU B 1 89  ? 36.276  -42.282 20.757  1.00 42.35  ? 89  LEU B CD2 1 
ATOM   2921  N  N   . ASP B 1 90  ? 35.601  -45.124 24.773  1.00 49.86  ? 90  ASP B N   1 
ATOM   2922  C  CA  . ASP B 1 90  ? 35.775  -45.846 26.028  1.00 48.90  ? 90  ASP B CA  1 
ATOM   2923  C  C   . ASP B 1 90  ? 37.247  -45.691 26.353  1.00 41.16  ? 90  ASP B C   1 
ATOM   2924  O  O   . ASP B 1 90  ? 38.078  -46.416 25.852  1.00 46.71  ? 90  ASP B O   1 
ATOM   2925  C  CB  . ASP B 1 90  ? 35.237  -47.275 25.948  1.00 48.94  ? 90  ASP B CB  1 
ATOM   2926  C  CG  . ASP B 1 90  ? 34.677  -47.777 27.277  1.00 67.03  ? 90  ASP B CG  1 
ATOM   2927  O  OD1 . ASP B 1 90  ? 33.698  -47.189 27.771  1.00 82.19  ? 90  ASP B OD1 1 
ATOM   2928  O  OD2 . ASP B 1 90  ? 35.211  -48.740 27.849  1.00 73.20  ? 90  ASP B OD2 1 
ATOM   2929  N  N   . GLY B 1 91  ? 37.590  -44.652 27.088  1.00 40.99  ? 91  GLY B N   1 
ATOM   2930  C  CA  . GLY B 1 91  ? 38.992  -44.365 27.318  1.00 39.70  ? 91  GLY B CA  1 
ATOM   2931  C  C   . GLY B 1 91  ? 39.415  -45.128 28.571  1.00 40.67  ? 91  GLY B C   1 
ATOM   2932  O  O   . GLY B 1 91  ? 38.560  -45.663 29.287  1.00 36.98  ? 91  GLY B O   1 
ATOM   2933  N  N   . PRO B 1 92  ? 40.719  -45.103 28.927  1.00 38.38  ? 92  PRO B N   1 
ATOM   2934  C  CA  . PRO B 1 92  ? 41.201  -45.831 30.095  1.00 33.42  ? 92  PRO B CA  1 
ATOM   2935  C  C   . PRO B 1 92  ? 40.457  -45.324 31.322  1.00 37.90  ? 92  PRO B C   1 
ATOM   2936  O  O   . PRO B 1 92  ? 40.085  -46.118 32.150  1.00 35.63  ? 92  PRO B O   1 
ATOM   2937  C  CB  . PRO B 1 92  ? 42.691  -45.508 30.224  1.00 32.95  ? 92  PRO B CB  1 
ATOM   2938  C  CG  . PRO B 1 92  ? 43.078  -44.755 28.947  1.00 38.53  ? 92  PRO B CG  1 
ATOM   2939  C  CD  . PRO B 1 92  ? 41.752  -44.247 28.311  1.00 44.77  ? 92  PRO B CD  1 
ATOM   2940  N  N   . VAL B 1 93  ? 40.265  -43.992 31.428  1.00 35.58  ? 93  VAL B N   1 
ATOM   2941  C  CA  . VAL B 1 93  ? 39.651  -43.378 32.587  1.00 36.62  ? 93  VAL B CA  1 
ATOM   2942  C  C   . VAL B 1 93  ? 38.271  -42.810 32.255  1.00 35.59  ? 93  VAL B C   1 
ATOM   2943  O  O   . VAL B 1 93  ? 37.334  -43.037 32.999  1.00 32.97  ? 93  VAL B O   1 
ATOM   2944  C  CB  . VAL B 1 93  ? 40.549  -42.293 33.183  1.00 38.94  ? 93  VAL B CB  1 
ATOM   2945  C  CG1 . VAL B 1 93  ? 39.820  -41.560 34.309  1.00 34.46  ? 93  VAL B CG1 1 
ATOM   2946  C  CG2 . VAL B 1 93  ? 41.863  -42.898 33.696  1.00 36.10  ? 93  VAL B CG2 1 
ATOM   2947  N  N   . HIS B 1 94  ? 38.157  -42.039 31.170  1.00 36.41  ? 94  HIS B N   1 
ATOM   2948  C  CA  . HIS B 1 94  ? 36.929  -41.290 30.908  1.00 33.35  ? 94  HIS B CA  1 
ATOM   2949  C  C   . HIS B 1 94  ? 36.233  -41.826 29.646  1.00 33.46  ? 94  HIS B C   1 
ATOM   2950  O  O   . HIS B 1 94  ? 36.889  -42.284 28.688  1.00 35.93  ? 94  HIS B O   1 
ATOM   2951  C  CB  . HIS B 1 94  ? 37.253  -39.800 30.771  1.00 29.33  ? 94  HIS B CB  1 
ATOM   2952  C  CG  . HIS B 1 94  ? 37.910  -39.157 31.918  1.00 28.60  ? 94  HIS B CG  1 
ATOM   2953  N  ND1 . HIS B 1 94  ? 37.253  -38.997 33.115  1.00 28.45  ? 94  HIS B ND1 1 
ATOM   2954  C  CD2 . HIS B 1 94  ? 39.154  -38.645 32.095  1.00 31.67  ? 94  HIS B CD2 1 
ATOM   2955  C  CE1 . HIS B 1 94  ? 38.056  -38.352 33.979  1.00 24.90  ? 94  HIS B CE1 1 
ATOM   2956  N  NE2 . HIS B 1 94  ? 39.208  -38.140 33.395  1.00 28.91  ? 94  HIS B NE2 1 
ATOM   2957  N  N   . ARG B 1 95  ? 34.910  -41.670 29.612  1.00 31.17  ? 95  ARG B N   1 
ATOM   2958  C  CA  . ARG B 1 95  ? 34.104  -42.226 28.532  1.00 40.28  ? 95  ARG B CA  1 
ATOM   2959  C  C   . ARG B 1 95  ? 33.220  -41.120 27.934  1.00 34.90  ? 95  ARG B C   1 
ATOM   2960  O  O   . ARG B 1 95  ? 32.623  -40.317 28.618  1.00 33.14  ? 95  ARG B O   1 
ATOM   2961  C  CB  . ARG B 1 95  ? 33.378  -43.387 29.227  1.00 44.06  ? 95  ARG B CB  1 
ATOM   2962  C  CG  . ARG B 1 95  ? 32.183  -44.091 28.625  1.00 47.39  ? 95  ARG B CG  1 
ATOM   2963  C  CD  . ARG B 1 95  ? 31.652  -45.080 29.668  1.00 53.50  ? 95  ARG B CD  1 
ATOM   2964  N  NE  . ARG B 1 95  ? 30.312  -45.484 29.214  1.00 61.49  ? 95  ARG B NE  1 
ATOM   2965  N  N   . ALA B 1 96  ? 33.164  -41.068 26.625  1.00 34.55  ? 96  ALA B N   1 
ATOM   2966  C  CA  . ALA B 1 96  ? 32.220  -40.243 25.902  1.00 35.50  ? 96  ALA B CA  1 
ATOM   2967  C  C   . ALA B 1 96  ? 31.073  -41.142 25.428  1.00 32.76  ? 96  ALA B C   1 
ATOM   2968  O  O   . ALA B 1 96  ? 31.250  -41.965 24.534  1.00 35.16  ? 96  ALA B O   1 
ATOM   2969  C  CB  . ALA B 1 96  ? 32.969  -39.542 24.756  1.00 33.51  ? 96  ALA B CB  1 
ATOM   2970  N  N   . VAL B 1 97  ? 29.917  -41.011 26.070  1.00 32.79  ? 97  VAL B N   1 
ATOM   2971  C  CA  . VAL B 1 97  ? 28.763  -41.826 25.739  1.00 33.89  ? 97  VAL B CA  1 
ATOM   2972  C  C   . VAL B 1 97  ? 28.099  -41.333 24.466  1.00 32.58  ? 97  VAL B C   1 
ATOM   2973  O  O   . VAL B 1 97  ? 28.202  -40.162 24.156  1.00 30.88  ? 97  VAL B O   1 
ATOM   2974  C  CB  . VAL B 1 97  ? 27.735  -41.855 26.872  1.00 37.85  ? 97  VAL B CB  1 
ATOM   2975  C  CG1 . VAL B 1 97  ? 28.387  -42.466 28.108  1.00 39.46  ? 97  VAL B CG1 1 
ATOM   2976  C  CG2 . VAL B 1 97  ? 27.168  -40.478 27.163  1.00 43.37  ? 97  VAL B CG2 1 
ATOM   2977  N  N   . ALA B 1 98  ? 27.414  -42.243 23.782  1.00 27.83  ? 98  ALA B N   1 
ATOM   2978  C  CA  . ALA B 1 98  ? 26.509  -41.887 22.716  1.00 32.92  ? 98  ALA B CA  1 
ATOM   2979  C  C   . ALA B 1 98  ? 25.065  -42.020 23.162  1.00 33.15  ? 98  ALA B C   1 
ATOM   2980  O  O   . ALA B 1 98  ? 24.698  -43.058 23.607  1.00 38.70  ? 98  ALA B O   1 
ATOM   2981  C  CB  . ALA B 1 98  ? 26.756  -42.828 21.584  1.00 37.97  ? 98  ALA B CB  1 
ATOM   2982  N  N   . THR B 1 99  ? 24.205  -41.036 22.971  1.00 38.65  ? 99  THR B N   1 
ATOM   2983  C  CA  . THR B 1 99  ? 22.825  -41.147 23.422  1.00 34.59  ? 99  THR B CA  1 
ATOM   2984  C  C   . THR B 1 99  ? 21.924  -40.825 22.233  1.00 33.92  ? 99  THR B C   1 
ATOM   2985  O  O   . THR B 1 99  ? 22.350  -40.217 21.269  1.00 23.71  ? 99  THR B O   1 
ATOM   2986  C  CB  . THR B 1 99  ? 22.551  -40.217 24.608  1.00 31.97  ? 99  THR B CB  1 
ATOM   2987  O  OG1 . THR B 1 99  ? 22.877  -38.904 24.174  1.00 30.89  ? 99  THR B OG1 1 
ATOM   2988  C  CG2 . THR B 1 99  ? 23.373  -40.589 25.818  1.00 34.22  ? 99  THR B CG2 1 
ATOM   2989  N  N   . PRO B 1 100 ? 20.654  -41.249 22.283  1.00 43.69  ? 100 PRO B N   1 
ATOM   2990  C  CA  . PRO B 1 100 ? 19.742  -41.115 21.146  1.00 39.61  ? 100 PRO B CA  1 
ATOM   2991  C  C   . PRO B 1 100 ? 19.352  -39.680 20.827  1.00 35.68  ? 100 PRO B C   1 
ATOM   2992  O  O   . PRO B 1 100 ? 19.148  -38.869 21.746  1.00 33.98  ? 100 PRO B O   1 
ATOM   2993  C  CB  . PRO B 1 100 ? 18.481  -41.869 21.628  1.00 39.74  ? 100 PRO B CB  1 
ATOM   2994  C  CG  . PRO B 1 100 ? 18.891  -42.665 22.826  1.00 37.71  ? 100 PRO B CG  1 
ATOM   2995  C  CD  . PRO B 1 100 ? 20.010  -41.873 23.457  1.00 44.61  ? 100 PRO B CD  1 
ATOM   2996  N  N   . GLY B 1 101 ? 19.164  -39.440 19.524  1.00 32.43  ? 101 GLY B N   1 
ATOM   2997  C  CA  . GLY B 1 101 ? 18.683  -38.159 19.055  1.00 30.31  ? 101 GLY B CA  1 
ATOM   2998  C  C   . GLY B 1 101 ? 18.535  -38.119 17.545  1.00 28.63  ? 101 GLY B C   1 
ATOM   2999  O  O   . GLY B 1 101 ? 19.475  -38.267 16.826  1.00 28.10  ? 101 GLY B O   1 
ATOM   3000  N  N   . ASP B 1 102 ? 17.350  -37.811 17.062  1.00 30.41  ? 102 ASP B N   1 
ATOM   3001  C  CA  . ASP B 1 102 ? 17.119  -37.720 15.633  1.00 33.25  ? 102 ASP B CA  1 
ATOM   3002  C  C   . ASP B 1 102 ? 17.122  -36.277 15.103  1.00 30.19  ? 102 ASP B C   1 
ATOM   3003  O  O   . ASP B 1 102 ? 17.539  -36.032 14.003  1.00 30.21  ? 102 ASP B O   1 
ATOM   3004  C  CB  . ASP B 1 102 ? 15.799  -38.398 15.332  1.00 36.46  ? 102 ASP B CB  1 
ATOM   3005  C  CG  . ASP B 1 102 ? 15.765  -39.898 15.608  1.00 35.28  ? 102 ASP B CG  1 
ATOM   3006  O  OD1 . ASP B 1 102 ? 16.833  -40.494 15.490  1.00 32.97  ? 102 ASP B OD1 1 
ATOM   3007  O  OD2 . ASP B 1 102 ? 14.689  -40.418 15.958  1.00 38.89  ? 102 ASP B OD2 1 
ATOM   3008  N  N   . LEU B 1 103 ? 16.610  -35.336 15.880  1.00 29.34  ? 103 LEU B N   1 
ATOM   3009  C  CA  . LEU B 1 103 ? 16.600  -33.933 15.503  1.00 30.94  ? 103 LEU B CA  1 
ATOM   3010  C  C   . LEU B 1 103 ? 17.198  -33.097 16.635  1.00 26.36  ? 103 LEU B C   1 
ATOM   3011  O  O   . LEU B 1 103 ? 16.955  -33.374 17.800  1.00 22.90  ? 103 LEU B O   1 
ATOM   3012  C  CB  . LEU B 1 103 ? 15.179  -33.420 15.243  1.00 34.44  ? 103 LEU B CB  1 
ATOM   3013  C  CG  . LEU B 1 103 ? 14.415  -34.125 14.131  1.00 38.96  ? 103 LEU B CG  1 
ATOM   3014  C  CD1 . LEU B 1 103 ? 12.953  -33.771 14.166  1.00 43.90  ? 103 LEU B CD1 1 
ATOM   3015  C  CD2 . LEU B 1 103 ? 15.057  -33.693 12.856  1.00 47.90  ? 103 LEU B CD2 1 
ATOM   3016  N  N   . LEU B 1 104 ? 17.908  -32.043 16.221  1.00 24.03  ? 104 LEU B N   1 
ATOM   3017  C  CA  . LEU B 1 104 ? 18.438  -31.020 17.081  1.00 22.77  ? 104 LEU B CA  1 
ATOM   3018  C  C   . LEU B 1 104 ? 17.840  -29.683 16.660  1.00 21.59  ? 104 LEU B C   1 
ATOM   3019  O  O   . LEU B 1 104 ? 17.881  -29.350 15.488  1.00 24.10  ? 104 LEU B O   1 
ATOM   3020  C  CB  . LEU B 1 104 ? 19.957  -31.005 16.957  1.00 24.60  ? 104 LEU B CB  1 
ATOM   3021  C  CG  . LEU B 1 104 ? 20.651  -29.771 17.557  1.00 24.77  ? 104 LEU B CG  1 
ATOM   3022  C  CD1 . LEU B 1 104 ? 20.656  -29.812 19.072  1.00 24.02  ? 104 LEU B CD1 1 
ATOM   3023  C  CD2 . LEU B 1 104 ? 21.997  -29.625 16.960  1.00 27.54  ? 104 LEU B CD2 1 
ATOM   3024  N  N   . PHE B 1 105 ? 17.326  -28.908 17.625  1.00 21.75  ? 105 PHE B N   1 
ATOM   3025  C  CA  . PHE B 1 105 ? 17.049  -27.495 17.403  1.00 21.78  ? 105 PHE B CA  1 
ATOM   3026  C  C   . PHE B 1 105 ? 17.965  -26.698 18.317  1.00 24.70  ? 105 PHE B C   1 
ATOM   3027  O  O   . PHE B 1 105 ? 17.905  -26.844 19.549  1.00 23.24  ? 105 PHE B O   1 
ATOM   3028  C  CB  . PHE B 1 105 ? 15.591  -27.157 17.666  1.00 23.94  ? 105 PHE B CB  1 
ATOM   3029  C  CG  . PHE B 1 105 ? 14.642  -27.984 16.814  1.00 26.78  ? 105 PHE B CG  1 
ATOM   3030  C  CD1 . PHE B 1 105 ? 14.340  -27.579 15.519  1.00 25.25  ? 105 PHE B CD1 1 
ATOM   3031  C  CD2 . PHE B 1 105 ? 14.035  -29.143 17.319  1.00 26.85  ? 105 PHE B CD2 1 
ATOM   3032  C  CE1 . PHE B 1 105 ? 13.489  -28.348 14.743  1.00 25.52  ? 105 PHE B CE1 1 
ATOM   3033  C  CE2 . PHE B 1 105 ? 13.167  -29.906 16.537  1.00 24.57  ? 105 PHE B CE2 1 
ATOM   3034  C  CZ  . PHE B 1 105 ? 12.884  -29.502 15.262  1.00 21.68  ? 105 PHE B CZ  1 
ATOM   3035  N  N   . HIS B 1 106 ? 18.874  -25.937 17.686  1.00 24.75  ? 106 HIS B N   1 
ATOM   3036  C  CA  . HIS B 1 106 ? 19.815  -25.078 18.391  1.00 25.19  ? 106 HIS B CA  1 
ATOM   3037  C  C   . HIS B 1 106 ? 19.302  -23.658 18.249  1.00 22.20  ? 106 HIS B C   1 
ATOM   3038  O  O   . HIS B 1 106 ? 19.434  -23.093 17.192  1.00 24.26  ? 106 HIS B O   1 
ATOM   3039  C  CB  . HIS B 1 106 ? 21.225  -25.241 17.825  1.00 22.19  ? 106 HIS B CB  1 
ATOM   3040  C  CG  . HIS B 1 106 ? 22.258  -24.397 18.533  1.00 23.99  ? 106 HIS B CG  1 
ATOM   3041  N  ND1 . HIS B 1 106 ? 23.432  -24.031 17.936  1.00 20.09  ? 106 HIS B ND1 1 
ATOM   3042  C  CD2 . HIS B 1 106 ? 22.260  -23.802 19.773  1.00 27.20  ? 106 HIS B CD2 1 
ATOM   3043  C  CE1 . HIS B 1 106 ? 24.117  -23.290 18.787  1.00 22.08  ? 106 HIS B CE1 1 
ATOM   3044  N  NE2 . HIS B 1 106 ? 23.430  -23.129 19.914  1.00 24.87  ? 106 HIS B NE2 1 
ATOM   3045  N  N   . ILE B 1 107 ? 18.628  -23.170 19.282  1.00 21.80  ? 107 ILE B N   1 
ATOM   3046  C  CA  . ILE B 1 107 ? 17.886  -21.933 19.246  1.00 21.00  ? 107 ILE B CA  1 
ATOM   3047  C  C   . ILE B 1 107 ? 18.640  -20.901 20.065  1.00 23.90  ? 107 ILE B C   1 
ATOM   3048  O  O   . ILE B 1 107 ? 18.968  -21.157 21.220  1.00 22.71  ? 107 ILE B O   1 
ATOM   3049  C  CB  . ILE B 1 107 ? 16.479  -22.172 19.794  1.00 23.24  ? 107 ILE B CB  1 
ATOM   3050  C  CG1 . ILE B 1 107 ? 15.752  -23.294 18.982  1.00 22.42  ? 107 ILE B CG1 1 
ATOM   3051  C  CG2 . ILE B 1 107 ? 15.697  -20.870 19.821  1.00 26.25  ? 107 ILE B CG2 1 
ATOM   3052  C  CD1 . ILE B 1 107 ? 14.458  -23.750 19.618  1.00 24.20  ? 107 ILE B CD1 1 
ATOM   3053  N  N   . ARG B 1 108 ? 18.919  -19.736 19.455  1.00 21.11  ? 108 ARG B N   1 
ATOM   3054  C  CA  . ARG B 1 108 ? 19.748  -18.750 20.102  1.00 22.26  ? 108 ARG B CA  1 
ATOM   3055  C  C   . ARG B 1 108 ? 19.089  -17.397 20.015  1.00 22.28  ? 108 ARG B C   1 
ATOM   3056  O  O   . ARG B 1 108 ? 18.474  -17.090 19.029  1.00 26.20  ? 108 ARG B O   1 
ATOM   3057  C  CB  . ARG B 1 108 ? 21.120  -18.684 19.446  1.00 24.25  ? 108 ARG B CB  1 
ATOM   3058  C  CG  . ARG B 1 108 ? 22.047  -19.814 19.844  1.00 29.09  ? 108 ARG B CG  1 
ATOM   3059  C  CD  . ARG B 1 108 ? 23.374  -19.779 19.126  1.00 30.12  ? 108 ARG B CD  1 
ATOM   3060  N  NE  . ARG B 1 108 ? 23.251  -20.141 17.707  1.00 36.52  ? 108 ARG B NE  1 
ATOM   3061  C  CZ  . ARG B 1 108 ? 24.324  -20.424 16.977  1.00 33.78  ? 108 ARG B CZ  1 
ATOM   3062  N  NH1 . ARG B 1 108 ? 25.515  -20.324 17.530  1.00 32.53  ? 108 ARG B NH1 1 
ATOM   3063  N  NH2 . ARG B 1 108 ? 24.227  -20.831 15.733  1.00 37.34  ? 108 ARG B NH2 1 
ATOM   3064  N  N   . ALA B 1 109 ? 19.292  -16.580 21.029  1.00 25.20  ? 109 ALA B N   1 
ATOM   3065  C  CA  . ALA B 1 109 ? 18.881  -15.191 20.948  1.00 26.59  ? 109 ALA B CA  1 
ATOM   3066  C  C   . ALA B 1 109 ? 19.545  -14.359 22.035  1.00 25.54  ? 109 ALA B C   1 
ATOM   3067  O  O   . ALA B 1 109 ? 20.235  -14.884 22.898  1.00 25.40  ? 109 ALA B O   1 
ATOM   3068  C  CB  . ALA B 1 109 ? 17.404  -15.151 21.127  1.00 26.92  ? 109 ALA B CB  1 
ATOM   3069  N  N   . SER B 1 110 ? 19.197  -13.074 22.055  1.00 26.77  ? 110 SER B N   1 
ATOM   3070  C  CA  . SER B 1 110 ? 19.704  -12.218 23.106  1.00 31.45  ? 110 SER B CA  1 
ATOM   3071  C  C   . SER B 1 110 ? 18.916  -12.414 24.390  1.00 31.83  ? 110 SER B C   1 
ATOM   3072  O  O   . SER B 1 110 ? 19.395  -12.027 25.428  1.00 39.86  ? 110 SER B O   1 
ATOM   3073  C  CB  . SER B 1 110 ? 19.678  -10.793 22.680  1.00 35.83  ? 110 SER B CB  1 
ATOM   3074  O  OG  . SER B 1 110 ? 18.343  -10.350 22.511  1.00 39.07  ? 110 SER B OG  1 
ATOM   3075  N  N   . ARG B 1 111 ? 17.744  -13.069 24.358  1.00 33.19  ? 111 ARG B N   1 
ATOM   3076  C  CA  . ARG B 1 111 ? 16.903  -13.215 25.547  1.00 29.65  ? 111 ARG B CA  1 
ATOM   3077  C  C   . ARG B 1 111 ? 16.190  -14.556 25.511  1.00 26.41  ? 111 ARG B C   1 
ATOM   3078  O  O   . ARG B 1 111 ? 15.738  -14.965 24.468  1.00 25.34  ? 111 ARG B O   1 
ATOM   3079  C  CB  . ARG B 1 111 ? 15.712  -12.258 25.473  1.00 32.96  ? 111 ARG B CB  1 
ATOM   3080  C  CG  . ARG B 1 111 ? 15.938  -10.758 25.403  1.00 41.23  ? 111 ARG B CG  1 
ATOM   3081  C  CD  . ARG B 1 111 ? 14.712  -10.156 24.741  1.00 50.01  ? 111 ARG B CD  1 
ATOM   3082  N  NE  . ARG B 1 111 ? 13.625  -10.201 25.732  1.00 48.67  ? 111 ARG B NE  1 
ATOM   3083  C  CZ  . ARG B 1 111 ? 13.454  -9.446  26.816  1.00 44.34  ? 111 ARG B CZ  1 
ATOM   3084  N  NH1 . ARG B 1 111 ? 14.125  -8.323  26.939  1.00 49.40  ? 111 ARG B NH1 1 
ATOM   3085  N  NH2 . ARG B 1 111 ? 12.547  -9.735  27.743  1.00 40.88  ? 111 ARG B NH2 1 
ATOM   3086  N  N   . LEU B 1 112 ? 16.046  -15.191 26.659  1.00 25.53  ? 112 LEU B N   1 
ATOM   3087  C  CA  . LEU B 1 112 ? 15.499  -16.531 26.748  1.00 28.36  ? 112 LEU B CA  1 
ATOM   3088  C  C   . LEU B 1 112 ? 14.061  -16.650 26.239  1.00 29.23  ? 112 LEU B C   1 
ATOM   3089  O  O   . LEU B 1 112 ? 13.665  -17.673 25.698  1.00 28.88  ? 112 LEU B O   1 
ATOM   3090  C  CB  . LEU B 1 112 ? 15.638  -16.912 28.222  1.00 28.59  ? 112 LEU B CB  1 
ATOM   3091  C  CG  . LEU B 1 112 ? 15.430  -18.383 28.525  1.00 36.96  ? 112 LEU B CG  1 
ATOM   3092  C  CD1 . LEU B 1 112 ? 16.326  -19.288 27.666  1.00 36.19  ? 112 LEU B CD1 1 
ATOM   3093  C  CD2 . LEU B 1 112 ? 15.725  -18.586 29.993  1.00 53.24  ? 112 LEU B CD2 1 
ATOM   3094  N  N   . ASP B 1 113 ? 13.258  -15.594 26.382  1.00 30.33  ? 113 ASP B N   1 
ATOM   3095  C  CA  . ASP B 1 113 ? 11.840  -15.673 26.077  1.00 27.02  ? 113 ASP B CA  1 
ATOM   3096  C  C   . ASP B 1 113 ? 11.631  -15.870 24.600  1.00 24.39  ? 113 ASP B C   1 
ATOM   3097  O  O   . ASP B 1 113 ? 10.731  -16.574 24.251  1.00 26.32  ? 113 ASP B O   1 
ATOM   3098  C  CB  . ASP B 1 113 ? 11.085  -14.424 26.490  1.00 30.32  ? 113 ASP B CB  1 
ATOM   3099  C  CG  . ASP B 1 113 ? 11.622  -13.096 25.953  1.00 30.41  ? 113 ASP B CG  1 
ATOM   3100  O  OD1 . ASP B 1 113 ? 12.697  -12.746 26.542  1.00 31.38  ? 113 ASP B OD1 1 
ATOM   3101  O  OD2 . ASP B 1 113 ? 10.943  -12.450 25.018  1.00 34.95  ? 113 ASP B OD2 1 
ATOM   3102  N  N   . LEU B 1 114 ? 12.451  -15.260 23.754  1.00 28.48  ? 114 LEU B N   1 
ATOM   3103  C  CA  . LEU B 1 114 ? 12.393  -15.457 22.315  1.00 28.13  ? 114 LEU B CA  1 
ATOM   3104  C  C   . LEU B 1 114 ? 12.743  -16.889 21.962  1.00 27.54  ? 114 LEU B C   1 
ATOM   3105  O  O   . LEU B 1 114 ? 12.128  -17.437 21.030  1.00 25.86  ? 114 LEU B O   1 
ATOM   3106  C  CB  . LEU B 1 114 ? 13.369  -14.549 21.565  1.00 28.48  ? 114 LEU B CB  1 
ATOM   3107  C  CG  . LEU B 1 114 ? 13.067  -13.065 21.653  1.00 34.62  ? 114 LEU B CG  1 
ATOM   3108  C  CD1 . LEU B 1 114 ? 14.153  -12.222 21.064  1.00 41.96  ? 114 LEU B CD1 1 
ATOM   3109  C  CD2 . LEU B 1 114 ? 11.819  -12.830 20.846  1.00 37.36  ? 114 LEU B CD2 1 
ATOM   3110  N  N   . CYS B 1 115 ? 13.770  -17.432 22.645  1.00 24.67  ? 115 CYS B N   1 
ATOM   3111  C  CA  . CYS B 1 115 ? 14.105  -18.825 22.476  1.00 22.51  ? 115 CYS B CA  1 
ATOM   3112  C  C   . CYS B 1 115 ? 12.903  -19.695 22.807  1.00 23.29  ? 115 CYS B C   1 
ATOM   3113  O  O   . CYS B 1 115 ? 12.568  -20.620 22.059  1.00 24.05  ? 115 CYS B O   1 
ATOM   3114  C  CB  . CYS B 1 115 ? 15.270  -19.228 23.337  1.00 25.06  ? 115 CYS B CB  1 
ATOM   3115  S  SG  . CYS B 1 115 ? 16.790  -18.411 22.818  1.00 27.05  ? 115 CYS B SG  1 
ATOM   3116  N  N   . PHE B 1 116 ? 12.247  -19.372 23.911  1.00 25.60  ? 116 PHE B N   1 
ATOM   3117  C  CA  . PHE B 1 116 ? 11.144  -20.165 24.402  1.00 23.64  ? 116 PHE B CA  1 
ATOM   3118  C  C   . PHE B 1 116 ? 9.973   -20.039 23.452  1.00 25.00  ? 116 PHE B C   1 
ATOM   3119  O  O   . PHE B 1 116 ? 9.291   -21.018 23.173  1.00 26.77  ? 116 PHE B O   1 
ATOM   3120  C  CB  . PHE B 1 116 ? 10.736  -19.666 25.781  1.00 27.26  ? 116 PHE B CB  1 
ATOM   3121  C  CG  . PHE B 1 116 ? 9.835   -20.664 26.486  1.00 23.84  ? 116 PHE B CG  1 
ATOM   3122  C  CD1 . PHE B 1 116 ? 10.367  -21.753 27.174  1.00 27.34  ? 116 PHE B CD1 1 
ATOM   3123  C  CD2 . PHE B 1 116 ? 8.466   -20.451 26.521  1.00 26.64  ? 116 PHE B CD2 1 
ATOM   3124  C  CE1 . PHE B 1 116 ? 9.541   -22.699 27.748  1.00 29.89  ? 116 PHE B CE1 1 
ATOM   3125  C  CE2 . PHE B 1 116 ? 7.633   -21.358 27.171  1.00 31.14  ? 116 PHE B CE2 1 
ATOM   3126  C  CZ  . PHE B 1 116 ? 8.173   -22.495 27.772  1.00 29.67  ? 116 PHE B CZ  1 
ATOM   3127  N  N   . ALA B 1 117 ? 9.736   -18.842 22.918  1.00 22.33  ? 117 ALA B N   1 
ATOM   3128  C  CA  . ALA B 1 117 ? 8.577   -18.660 22.059  1.00 22.82  ? 117 ALA B CA  1 
ATOM   3129  C  C   . ALA B 1 117 ? 8.703   -19.496 20.794  1.00 22.37  ? 117 ALA B C   1 
ATOM   3130  O  O   . ALA B 1 117 ? 7.748   -20.134 20.369  1.00 22.70  ? 117 ALA B O   1 
ATOM   3131  C  CB  . ALA B 1 117 ? 8.400   -17.189 21.776  1.00 23.76  ? 117 ALA B CB  1 
ATOM   3132  N  N   . LEU B 1 118 ? 9.916   -19.514 20.216  1.00 26.41  ? 118 LEU B N   1 
ATOM   3133  C  CA  . LEU B 1 118 ? 10.172  -20.296 19.015  1.00 25.84  ? 118 LEU B CA  1 
ATOM   3134  C  C   . LEU B 1 118 ? 10.112  -21.797 19.346  1.00 24.29  ? 118 LEU B C   1 
ATOM   3135  O  O   . LEU B 1 118 ? 9.513   -22.594 18.615  1.00 22.76  ? 118 LEU B O   1 
ATOM   3136  C  CB  . LEU B 1 118 ? 11.496  -19.856 18.387  1.00 26.54  ? 118 LEU B CB  1 
ATOM   3137  C  CG  . LEU B 1 118 ? 11.883  -20.641 17.123  1.00 31.53  ? 118 LEU B CG  1 
ATOM   3138  C  CD1 . LEU B 1 118 ? 10.790  -20.595 16.009  1.00 34.23  ? 118 LEU B CD1 1 
ATOM   3139  C  CD2 . LEU B 1 118 ? 13.212  -20.237 16.543  1.00 32.82  ? 118 LEU B CD2 1 
ATOM   3140  N  N   . ALA B 1 119 ? 10.731  -22.219 20.453  1.00 22.08  ? 119 ALA B N   1 
ATOM   3141  C  CA  . ALA B 1 119 ? 10.671  -23.631 20.826  1.00 26.47  ? 119 ALA B CA  1 
ATOM   3142  C  C   . ALA B 1 119 ? 9.227   -24.108 21.002  1.00 26.93  ? 119 ALA B C   1 
ATOM   3143  O  O   . ALA B 1 119 ? 8.882   -25.195 20.631  1.00 23.77  ? 119 ALA B O   1 
ATOM   3144  C  CB  . ALA B 1 119 ? 11.463  -23.887 22.092  1.00 24.42  ? 119 ALA B CB  1 
ATOM   3145  N  N   . THR B 1 120 ? 8.393   -23.287 21.620  1.00 29.12  ? 120 THR B N   1 
ATOM   3146  C  CA  . THR B 1 120 ? 6.995   -23.595 21.812  1.00 29.70  ? 120 THR B CA  1 
ATOM   3147  C  C   . THR B 1 120 ? 6.317   -23.808 20.463  1.00 32.76  ? 120 THR B C   1 
ATOM   3148  O  O   . THR B 1 120 ? 5.567   -24.758 20.333  1.00 23.81  ? 120 THR B O   1 
ATOM   3149  C  CB  . THR B 1 120 ? 6.339   -22.418 22.531  1.00 32.03  ? 120 THR B CB  1 
ATOM   3150  O  OG1 . THR B 1 120 ? 6.800   -22.422 23.872  1.00 28.97  ? 120 THR B OG1 1 
ATOM   3151  C  CG2 . THR B 1 120 ? 4.858   -22.647 22.721  1.00 37.87  ? 120 THR B CG2 1 
ATOM   3152  N  N   . GLU B 1 121 ? 6.515   -22.891 19.496  1.00 31.24  ? 121 GLU B N   1 
ATOM   3153  C  CA  . GLU B 1 121 ? 5.922   -23.084 18.178  1.00 31.99  ? 121 GLU B CA  1 
ATOM   3154  C  C   . GLU B 1 121 ? 6.392   -24.395 17.514  1.00 33.86  ? 121 GLU B C   1 
ATOM   3155  O  O   . GLU B 1 121 ? 5.615   -25.092 16.860  1.00 27.85  ? 121 GLU B O   1 
ATOM   3156  C  CB  . GLU B 1 121 ? 6.209   -21.982 17.164  1.00 29.41  ? 121 GLU B CB  1 
ATOM   3157  C  CG  . GLU B 1 121 ? 5.601   -20.647 17.567  1.00 35.48  ? 121 GLU B CG  1 
ATOM   3158  C  CD  . GLU B 1 121 ? 4.102   -20.592 17.500  1.00 35.96  ? 121 GLU B CD  1 
ATOM   3159  O  OE1 . GLU B 1 121 ? 3.498   -21.442 16.811  1.00 33.50  ? 121 GLU B OE1 1 
ATOM   3160  O  OE2 . GLU B 1 121 ? 3.609   -19.663 18.153  1.00 39.72  ? 121 GLU B OE2 1 
ATOM   3161  N  N   . ILE B 1 122 ? 7.680   -24.719 17.651  1.00 28.10  ? 122 ILE B N   1 
ATOM   3162  C  CA  . ILE B 1 122 ? 8.201   -25.877 16.986  1.00 28.57  ? 122 ILE B CA  1 
ATOM   3163  C  C   . ILE B 1 122 ? 7.581   -27.131 17.586  1.00 30.48  ? 122 ILE B C   1 
ATOM   3164  O  O   . ILE B 1 122 ? 7.034   -27.976 16.879  1.00 29.24  ? 122 ILE B O   1 
ATOM   3165  C  CB  . ILE B 1 122 ? 9.731   -25.844 16.996  1.00 27.37  ? 122 ILE B CB  1 
ATOM   3166  C  CG1 . ILE B 1 122 ? 10.232  -24.812 16.006  1.00 24.97  ? 122 ILE B CG1 1 
ATOM   3167  C  CG2 . ILE B 1 122 ? 10.291  -27.225 16.641  1.00 29.12  ? 122 ILE B CG2 1 
ATOM   3168  C  CD1 . ILE B 1 122 ? 11.671  -24.488 16.246  1.00 27.63  ? 122 ILE B CD1 1 
ATOM   3169  N  N   . MET B 1 123 ? 7.636   -27.242 18.905  1.00 32.31  ? 123 MET B N   1 
ATOM   3170  C  CA  . MET B 1 123 ? 7.125   -28.427 19.576  1.00 34.55  ? 123 MET B CA  1 
ATOM   3171  C  C   . MET B 1 123 ? 5.616   -28.536 19.423  1.00 33.30  ? 123 MET B C   1 
ATOM   3172  O  O   . MET B 1 123 ? 5.096   -29.626 19.448  1.00 33.06  ? 123 MET B O   1 
ATOM   3173  C  CB  . MET B 1 123 ? 7.463   -28.425 21.075  1.00 37.54  ? 123 MET B CB  1 
ATOM   3174  C  CG  . MET B 1 123 ? 8.918   -28.704 21.334  1.00 48.48  ? 123 MET B CG  1 
ATOM   3175  S  SD  . MET B 1 123 ? 9.434   -30.352 20.813  1.00 48.40  ? 123 MET B SD  1 
ATOM   3176  C  CE  . MET B 1 123 ? 8.129   -31.340 21.595  1.00 39.51  ? 123 MET B CE  1 
ATOM   3177  N  N   . GLY B 1 124 ? 4.918   -27.409 19.272  1.00 28.61  ? 124 GLY B N   1 
ATOM   3178  C  CA  . GLY B 1 124 ? 3.489   -27.393 19.024  1.00 29.17  ? 124 GLY B CA  1 
ATOM   3179  C  C   . GLY B 1 124 ? 3.135   -28.146 17.759  1.00 32.18  ? 124 GLY B C   1 
ATOM   3180  O  O   . GLY B 1 124 ? 2.186   -28.918 17.770  1.00 38.24  ? 124 GLY B O   1 
ATOM   3181  N  N   . ARG B 1 125 ? 3.929   -27.940 16.703  1.00 30.44  ? 125 ARG B N   1 
ATOM   3182  C  CA  . ARG B 1 125 ? 3.705   -28.583 15.422  1.00 32.35  ? 125 ARG B CA  1 
ATOM   3183  C  C   . ARG B 1 125 ? 4.163   -30.047 15.461  1.00 34.21  ? 125 ARG B C   1 
ATOM   3184  O  O   . ARG B 1 125 ? 3.808   -30.835 14.610  1.00 34.20  ? 125 ARG B O   1 
ATOM   3185  C  CB  . ARG B 1 125 ? 4.389   -27.734 14.343  1.00 32.21  ? 125 ARG B CB  1 
ATOM   3186  C  CG  . ARG B 1 125 ? 3.950   -26.256 14.296  1.00 42.82  ? 125 ARG B CG  1 
ATOM   3187  C  CD  . ARG B 1 125 ? 3.219   -25.568 13.101  1.00 51.56  ? 125 ARG B CD  1 
ATOM   3188  N  NE  . ARG B 1 125 ? 3.236   -26.564 12.009  1.00 64.44  ? 125 ARG B NE  1 
ATOM   3189  C  CZ  . ARG B 1 125 ? 3.906   -26.566 10.831  1.00 63.21  ? 125 ARG B CZ  1 
ATOM   3190  N  NH1 . ARG B 1 125 ? 4.321   -25.435 10.306  1.00 72.69  ? 125 ARG B NH1 1 
ATOM   3191  N  NH2 . ARG B 1 125 ? 4.107   -27.683 10.145  1.00 55.38  ? 125 ARG B NH2 1 
ATOM   3192  N  N   . LEU B 1 126 ? 4.997   -30.431 16.426  1.00 34.58  ? 126 LEU B N   1 
ATOM   3193  C  CA  . LEU B 1 126 ? 5.529   -31.777 16.459  1.00 32.29  ? 126 LEU B CA  1 
ATOM   3194  C  C   . LEU B 1 126 ? 4.842   -32.658 17.511  1.00 31.61  ? 126 LEU B C   1 
ATOM   3195  O  O   . LEU B 1 126 ? 5.251   -33.798 17.649  1.00 32.27  ? 126 LEU B O   1 
ATOM   3196  C  CB  . LEU B 1 126 ? 7.037   -31.726 16.714  1.00 28.92  ? 126 LEU B CB  1 
ATOM   3197  C  CG  . LEU B 1 126 ? 7.880   -31.183 15.565  1.00 32.83  ? 126 LEU B CG  1 
ATOM   3198  C  CD1 . LEU B 1 126 ? 9.354   -31.183 15.893  1.00 35.68  ? 126 LEU B CD1 1 
ATOM   3199  C  CD2 . LEU B 1 126 ? 7.688   -31.999 14.304  1.00 35.27  ? 126 LEU B CD2 1 
ATOM   3200  N  N   . ARG B 1 127 ? 3.926   -32.117 18.323  1.00 36.11  ? 127 ARG B N   1 
ATOM   3201  C  CA  . ARG B 1 127 ? 3.274   -32.855 19.394  1.00 40.27  ? 127 ARG B CA  1 
ATOM   3202  C  C   . ARG B 1 127 ? 2.729   -34.151 18.762  1.00 44.09  ? 127 ARG B C   1 
ATOM   3203  O  O   . ARG B 1 127 ? 2.143   -34.160 17.669  1.00 38.70  ? 127 ARG B O   1 
ATOM   3204  C  CB  . ARG B 1 127 ? 2.011   -32.207 19.985  1.00 46.03  ? 127 ARG B CB  1 
ATOM   3205  C  CG  . ARG B 1 127 ? 1.970   -31.064 20.970  1.00 62.85  ? 127 ARG B CG  1 
ATOM   3206  C  CD  . ARG B 1 127 ? 2.508   -31.342 22.337  1.00 89.67  ? 127 ARG B CD  1 
ATOM   3207  N  NE  . ARG B 1 127 ? 3.016   -30.093 22.945  1.00 105.92 ? 127 ARG B NE  1 
ATOM   3208  C  CZ  . ARG B 1 127 ? 4.283   -29.801 23.346  1.00 94.57  ? 127 ARG B CZ  1 
ATOM   3209  N  NH1 . ARG B 1 127 ? 4.518   -28.642 23.980  1.00 68.67  ? 127 ARG B NH1 1 
ATOM   3210  N  NH2 . ARG B 1 127 ? 5.283   -30.680 23.182  1.00 94.50  ? 127 ARG B NH2 1 
ATOM   3211  N  N   . GLY B 1 128 ? 2.960   -35.284 19.408  1.00 40.76  ? 128 GLY B N   1 
ATOM   3212  C  CA  . GLY B 1 128 ? 2.397   -36.512 18.889  1.00 35.81  ? 128 GLY B CA  1 
ATOM   3213  C  C   . GLY B 1 128 ? 3.318   -37.202 17.895  1.00 36.49  ? 128 GLY B C   1 
ATOM   3214  O  O   . GLY B 1 128 ? 3.084   -38.339 17.585  1.00 47.44  ? 128 GLY B O   1 
ATOM   3215  N  N   . ALA B 1 129 ? 4.345   -36.558 17.354  1.00 37.02  ? 129 ALA B N   1 
ATOM   3216  C  CA  . ALA B 1 129 ? 5.218   -37.198 16.380  1.00 34.96  ? 129 ALA B CA  1 
ATOM   3217  C  C   . ALA B 1 129 ? 6.628   -37.512 16.911  1.00 34.55  ? 129 ALA B C   1 
ATOM   3218  O  O   . ALA B 1 129 ? 7.384   -38.264 16.260  1.00 30.79  ? 129 ALA B O   1 
ATOM   3219  C  CB  . ALA B 1 129 ? 5.309   -36.290 15.168  1.00 36.68  ? 129 ALA B CB  1 
ATOM   3220  N  N   . VAL B 1 130 ? 7.017   -36.834 18.012  1.00 33.43  ? 130 VAL B N   1 
ATOM   3221  C  CA  . VAL B 1 130 ? 8.372   -36.931 18.524  1.00 34.53  ? 130 VAL B CA  1 
ATOM   3222  C  C   . VAL B 1 130 ? 8.333   -37.143 20.044  1.00 35.07  ? 130 VAL B C   1 
ATOM   3223  O  O   . VAL B 1 130 ? 7.354   -36.893 20.708  1.00 35.58  ? 130 VAL B O   1 
ATOM   3224  C  CB  . VAL B 1 130 ? 9.216   -35.697 18.144  1.00 32.70  ? 130 VAL B CB  1 
ATOM   3225  C  CG1 . VAL B 1 130 ? 9.226   -35.412 16.656  1.00 38.52  ? 130 VAL B CG1 1 
ATOM   3226  C  CG2 . VAL B 1 130 ? 8.744   -34.448 18.859  1.00 33.12  ? 130 VAL B CG2 1 
ATOM   3227  N  N   . THR B 1 131 ? 9.457   -37.542 20.610  1.00 35.35  ? 131 THR B N   1 
ATOM   3228  C  CA  . THR B 1 131 ? 9.604   -37.685 22.043  1.00 37.11  ? 131 THR B CA  1 
ATOM   3229  C  C   . THR B 1 131 ? 10.804  -36.849 22.437  1.00 36.69  ? 131 THR B C   1 
ATOM   3230  O  O   . THR B 1 131 ? 11.896  -37.021 21.889  1.00 40.70  ? 131 THR B O   1 
ATOM   3231  C  CB  . THR B 1 131 ? 9.831   -39.162 22.380  1.00 38.98  ? 131 THR B CB  1 
ATOM   3232  O  OG1 . THR B 1 131 ? 8.619   -39.777 21.966  1.00 42.83  ? 131 THR B OG1 1 
ATOM   3233  C  CG2 . THR B 1 131 ? 10.093  -39.366 23.852  1.00 32.90  ? 131 THR B CG2 1 
ATOM   3234  N  N   . PRO B 1 132 ? 10.679  -35.965 23.431  1.00 41.49  ? 132 PRO B N   1 
ATOM   3235  C  CA  . PRO B 1 132 ? 11.818  -35.181 23.878  1.00 40.77  ? 132 PRO B CA  1 
ATOM   3236  C  C   . PRO B 1 132 ? 12.887  -36.089 24.473  1.00 40.22  ? 132 PRO B C   1 
ATOM   3237  O  O   . PRO B 1 132 ? 12.557  -36.928 25.247  1.00 38.70  ? 132 PRO B O   1 
ATOM   3238  C  CB  . PRO B 1 132 ? 11.200  -34.251 24.899  1.00 38.66  ? 132 PRO B CB  1 
ATOM   3239  C  CG  . PRO B 1 132 ? 9.761   -34.268 24.596  1.00 43.68  ? 132 PRO B CG  1 
ATOM   3240  C  CD  . PRO B 1 132 ? 9.468   -35.688 24.185  1.00 41.95  ? 132 PRO B CD  1 
ATOM   3241  N  N   . GLN B 1 133 ? 14.159  -35.910 24.144  1.00 34.14  ? 133 GLN B N   1 
ATOM   3242  C  CA  . GLN B 1 133 ? 15.234  -36.590 24.847  1.00 34.17  ? 133 GLN B CA  1 
ATOM   3243  C  C   . GLN B 1 133 ? 16.013  -35.621 25.747  1.00 34.57  ? 133 GLN B C   1 
ATOM   3244  O  O   . GLN B 1 133 ? 16.688  -36.064 26.672  1.00 28.89  ? 133 GLN B O   1 
ATOM   3245  C  CB  . GLN B 1 133 ? 16.335  -37.102 23.922  1.00 33.51  ? 133 GLN B CB  1 
ATOM   3246  C  CG  . GLN B 1 133 ? 15.841  -38.134 22.928  1.00 46.29  ? 133 GLN B CG  1 
ATOM   3247  C  CD  . GLN B 1 133 ? 15.356  -39.392 23.627  1.00 51.05  ? 133 GLN B CD  1 
ATOM   3248  O  OE1 . GLN B 1 133 ? 16.038  -39.918 24.518  1.00 42.61  ? 133 GLN B OE1 1 
ATOM   3249  N  NE2 . GLN B 1 133 ? 14.152  -39.825 23.262  1.00 40.10  ? 133 GLN B NE2 1 
ATOM   3250  N  N   . ASP B 1 134 ? 16.095  -34.328 25.399  1.00 34.24  ? 134 ASP B N   1 
ATOM   3251  C  CA  . ASP B 1 134 ? 16.902  -33.410 26.195  1.00 31.99  ? 134 ASP B CA  1 
ATOM   3252  C  C   . ASP B 1 134 ? 16.419  -31.999 25.859  1.00 31.46  ? 134 ASP B C   1 
ATOM   3253  O  O   . ASP B 1 134 ? 16.017  -31.716 24.707  1.00 30.94  ? 134 ASP B O   1 
ATOM   3254  C  CB  . ASP B 1 134 ? 18.387  -33.625 25.947  1.00 32.50  ? 134 ASP B CB  1 
ATOM   3255  C  CG  . ASP B 1 134 ? 19.330  -33.025 26.962  1.00 33.52  ? 134 ASP B CG  1 
ATOM   3256  O  OD1 . ASP B 1 134 ? 18.832  -32.814 28.018  1.00 31.08  ? 134 ASP B OD1 1 
ATOM   3257  O  OD2 . ASP B 1 134 ? 20.540  -32.792 26.672  1.00 35.17  ? 134 ASP B OD2 1 
ATOM   3258  N  N   . GLU B 1 135 ? 16.396  -31.150 26.890  1.00 28.03  ? 135 GLU B N   1 
ATOM   3259  C  CA  . GLU B 1 135 ? 15.994  -29.761 26.759  1.00 24.56  ? 135 GLU B CA  1 
ATOM   3260  C  C   . GLU B 1 135 ? 16.855  -28.972 27.731  1.00 25.68  ? 135 GLU B C   1 
ATOM   3261  O  O   . GLU B 1 135 ? 16.819  -29.255 28.914  1.00 27.20  ? 135 GLU B O   1 
ATOM   3262  C  CB  . GLU B 1 135 ? 14.520  -29.588 27.116  1.00 24.03  ? 135 GLU B CB  1 
ATOM   3263  C  CG  . GLU B 1 135 ? 14.080  -28.134 27.066  1.00 26.98  ? 135 GLU B CG  1 
ATOM   3264  C  CD  . GLU B 1 135 ? 12.641  -27.866 27.435  1.00 31.19  ? 135 GLU B CD  1 
ATOM   3265  O  OE1 . GLU B 1 135 ? 11.966  -28.858 27.741  1.00 32.69  ? 135 GLU B OE1 1 
ATOM   3266  O  OE2 . GLU B 1 135 ? 12.208  -26.701 27.457  1.00 30.78  ? 135 GLU B OE2 1 
ATOM   3267  N  N   . VAL B 1 136 ? 17.669  -28.043 27.251  1.00 23.50  ? 136 VAL B N   1 
ATOM   3268  C  CA  . VAL B 1 136 ? 18.558  -27.295 28.107  1.00 25.57  ? 136 VAL B CA  1 
ATOM   3269  C  C   . VAL B 1 136 ? 18.348  -25.806 27.806  1.00 26.55  ? 136 VAL B C   1 
ATOM   3270  O  O   . VAL B 1 136 ? 18.311  -25.400 26.655  1.00 28.14  ? 136 VAL B O   1 
ATOM   3271  C  CB  . VAL B 1 136 ? 20.019  -27.709 27.890  1.00 30.50  ? 136 VAL B CB  1 
ATOM   3272  C  CG1 . VAL B 1 136 ? 20.992  -26.812 28.611  1.00 33.03  ? 136 VAL B CG1 1 
ATOM   3273  C  CG2 . VAL B 1 136 ? 20.276  -29.090 28.364  1.00 29.23  ? 136 VAL B CG2 1 
ATOM   3274  N  N   . HIS B 1 137 ? 18.221  -25.012 28.880  1.00 25.76  ? 137 HIS B N   1 
ATOM   3275  C  CA  . HIS B 1 137 ? 18.061  -23.571 28.816  1.00 25.46  ? 137 HIS B CA  1 
ATOM   3276  C  C   . HIS B 1 137 ? 19.392  -23.007 29.266  1.00 25.72  ? 137 HIS B C   1 
ATOM   3277  O  O   . HIS B 1 137 ? 19.789  -23.225 30.388  1.00 21.89  ? 137 HIS B O   1 
ATOM   3278  C  CB  . HIS B 1 137 ? 16.903  -23.060 29.673  1.00 23.99  ? 137 HIS B CB  1 
ATOM   3279  C  CG  . HIS B 1 137 ? 15.573  -23.592 29.295  1.00 25.96  ? 137 HIS B CG  1 
ATOM   3280  N  ND1 . HIS B 1 137 ? 14.426  -23.052 29.832  1.00 26.60  ? 137 HIS B ND1 1 
ATOM   3281  C  CD2 . HIS B 1 137 ? 15.176  -24.572 28.454  1.00 24.84  ? 137 HIS B CD2 1 
ATOM   3282  C  CE1 . HIS B 1 137 ? 13.386  -23.714 29.330  1.00 29.12  ? 137 HIS B CE1 1 
ATOM   3283  N  NE2 . HIS B 1 137 ? 13.805  -24.653 28.512  1.00 24.33  ? 137 HIS B NE2 1 
ATOM   3284  N  N   . GLY B 1 138 ? 20.117  -22.410 28.310  1.00 26.60  ? 138 GLY B N   1 
ATOM   3285  C  CA  . GLY B 1 138 ? 21.470  -21.958 28.549  1.00 24.35  ? 138 GLY B CA  1 
ATOM   3286  C  C   . GLY B 1 138 ? 21.488  -20.449 28.763  1.00 22.52  ? 138 GLY B C   1 
ATOM   3287  O  O   . GLY B 1 138 ? 20.674  -19.730 28.157  1.00 23.21  ? 138 GLY B O   1 
ATOM   3288  N  N   . PHE B 1 139 ? 22.491  -19.989 29.510  1.00 21.73  ? 139 PHE B N   1 
ATOM   3289  C  CA  . PHE B 1 139 ? 22.710  -18.567 29.754  1.00 24.01  ? 139 PHE B CA  1 
ATOM   3290  C  C   . PHE B 1 139 ? 24.209  -18.284 29.769  1.00 25.16  ? 139 PHE B C   1 
ATOM   3291  O  O   . PHE B 1 139 ? 24.902  -19.006 30.454  1.00 31.36  ? 139 PHE B O   1 
ATOM   3292  C  CB  . PHE B 1 139 ? 22.098  -18.127 31.093  1.00 27.47  ? 139 PHE B CB  1 
ATOM   3293  C  CG  . PHE B 1 139 ? 22.317  -19.091 32.263  1.00 33.50  ? 139 PHE B CG  1 
ATOM   3294  C  CD1 . PHE B 1 139 ? 21.442  -20.150 32.482  1.00 32.52  ? 139 PHE B CD1 1 
ATOM   3295  C  CD2 . PHE B 1 139 ? 23.417  -18.968 33.107  1.00 38.20  ? 139 PHE B CD2 1 
ATOM   3296  C  CE1 . PHE B 1 139 ? 21.623  -21.025 33.517  1.00 33.98  ? 139 PHE B CE1 1 
ATOM   3297  C  CE2 . PHE B 1 139 ? 23.595  -19.846 34.173  1.00 37.03  ? 139 PHE B CE2 1 
ATOM   3298  C  CZ  . PHE B 1 139 ? 22.707  -20.877 34.358  1.00 38.28  ? 139 PHE B CZ  1 
ATOM   3299  N  N   . LYS B 1 140 ? 24.703  -17.259 29.044  1.00 29.24  ? 140 LYS B N   1 
ATOM   3300  C  CA  . LYS B 1 140 ? 26.129  -16.945 29.044  1.00 34.65  ? 140 LYS B CA  1 
ATOM   3301  C  C   . LYS B 1 140 ? 26.328  -16.010 30.218  1.00 29.85  ? 140 LYS B C   1 
ATOM   3302  O  O   . LYS B 1 140 ? 25.468  -15.206 30.461  1.00 25.63  ? 140 LYS B O   1 
ATOM   3303  C  CB  . LYS B 1 140 ? 26.576  -16.421 27.670  1.00 51.31  ? 140 LYS B CB  1 
ATOM   3304  C  CG  . LYS B 1 140 ? 28.020  -16.732 27.180  1.00 70.57  ? 140 LYS B CG  1 
ATOM   3305  C  CD  . LYS B 1 140 ? 28.667  -18.088 27.504  1.00 70.39  ? 140 LYS B CD  1 
ATOM   3306  C  CE  . LYS B 1 140 ? 30.134  -18.284 27.122  1.00 62.13  ? 140 LYS B CE  1 
ATOM   3307  N  NZ  . LYS B 1 140 ? 30.568  -17.709 25.830  1.00 51.47  ? 140 LYS B NZ  1 
ATOM   3308  N  N   . TYR B 1 141 ? 27.428  -16.153 30.963  1.00 31.77  ? 141 TYR B N   1 
ATOM   3309  C  CA  . TYR B 1 141 ? 27.793  -15.209 32.012  1.00 29.50  ? 141 TYR B CA  1 
ATOM   3310  C  C   . TYR B 1 141 ? 28.322  -13.926 31.404  1.00 36.90  ? 141 TYR B C   1 
ATOM   3311  O  O   . TYR B 1 141 ? 28.601  -13.843 30.226  1.00 30.85  ? 141 TYR B O   1 
ATOM   3312  C  CB  . TYR B 1 141 ? 28.835  -15.742 32.959  1.00 29.12  ? 141 TYR B CB  1 
ATOM   3313  C  CG  . TYR B 1 141 ? 28.304  -16.772 33.944  1.00 29.89  ? 141 TYR B CG  1 
ATOM   3314  C  CD1 . TYR B 1 141 ? 27.749  -16.441 35.134  1.00 32.96  ? 141 TYR B CD1 1 
ATOM   3315  C  CD2 . TYR B 1 141 ? 28.461  -18.097 33.694  1.00 36.97  ? 141 TYR B CD2 1 
ATOM   3316  C  CE1 . TYR B 1 141 ? 27.329  -17.398 36.036  1.00 36.33  ? 141 TYR B CE1 1 
ATOM   3317  C  CE2 . TYR B 1 141 ? 28.056  -19.073 34.569  1.00 39.20  ? 141 TYR B CE2 1 
ATOM   3318  C  CZ  . TYR B 1 141 ? 27.475  -18.725 35.752  1.00 38.15  ? 141 TYR B CZ  1 
ATOM   3319  O  OH  . TYR B 1 141 ? 27.057  -19.771 36.504  1.00 40.63  ? 141 TYR B OH  1 
ATOM   3320  N  N   . PHE B 1 142 ? 28.350  -12.862 32.188  1.00 55.49  ? 142 PHE B N   1 
ATOM   3321  C  CA  . PHE B 1 142 ? 28.255  -11.538 31.589  1.00 55.36  ? 142 PHE B CA  1 
ATOM   3322  C  C   . PHE B 1 142 ? 29.606  -11.199 30.950  1.00 46.38  ? 142 PHE B C   1 
ATOM   3323  O  O   . PHE B 1 142 ? 29.598  -10.304 30.107  1.00 43.16  ? 142 PHE B O   1 
ATOM   3324  C  CB  . PHE B 1 142 ? 27.711  -10.446 32.552  1.00 66.81  ? 142 PHE B CB  1 
ATOM   3325  C  CG  . PHE B 1 142 ? 28.775  -9.832  33.461  1.00 74.10  ? 142 PHE B CG  1 
ATOM   3326  C  CD1 . PHE B 1 142 ? 29.133  -10.479 34.653  1.00 87.02  ? 142 PHE B CD1 1 
ATOM   3327  C  CD2 . PHE B 1 142 ? 29.489  -8.684  33.062  1.00 68.72  ? 142 PHE B CD2 1 
ATOM   3328  C  CE1 . PHE B 1 142 ? 30.164  -9.964  35.438  1.00 97.24  ? 142 PHE B CE1 1 
ATOM   3329  C  CE2 . PHE B 1 142 ? 30.528  -8.184  33.834  1.00 76.14  ? 142 PHE B CE2 1 
ATOM   3330  C  CZ  . PHE B 1 142 ? 30.854  -8.814  35.028  1.00 91.23  ? 142 PHE B CZ  1 
ATOM   3331  N  N   . ASP B 1 143 ? 30.733  -11.873 31.295  1.00 35.14  ? 143 ASP B N   1 
ATOM   3332  C  CA  . ASP B 1 143 ? 31.970  -11.544 30.591  1.00 37.99  ? 143 ASP B CA  1 
ATOM   3333  C  C   . ASP B 1 143 ? 32.443  -12.695 29.733  1.00 34.88  ? 143 ASP B C   1 
ATOM   3334  O  O   . ASP B 1 143 ? 33.624  -12.936 29.669  1.00 37.04  ? 143 ASP B O   1 
ATOM   3335  C  CB  . ASP B 1 143 ? 33.107  -11.122 31.488  1.00 42.98  ? 143 ASP B CB  1 
ATOM   3336  C  CG  . ASP B 1 143 ? 32.976  -11.734 32.878  1.00 64.54  ? 143 ASP B CG  1 
ATOM   3337  O  OD1 . ASP B 1 143 ? 31.974  -12.576 33.124  1.00 47.37  ? 143 ASP B OD1 1 
ATOM   3338  O  OD2 . ASP B 1 143 ? 33.834  -11.306 33.715  1.00 85.36  ? 143 ASP B OD2 1 
ATOM   3339  N  N   . GLU B 1 144 ? 31.509  -13.309 29.019  1.00 27.83  ? 144 GLU B N   1 
ATOM   3340  C  CA  . GLU B 1 144 ? 31.720  -14.510 28.234  1.00 29.47  ? 144 GLU B CA  1 
ATOM   3341  C  C   . GLU B 1 144 ? 32.385  -15.667 29.007  1.00 26.48  ? 144 GLU B C   1 
ATOM   3342  O  O   . GLU B 1 144 ? 32.913  -16.570 28.365  1.00 24.49  ? 144 GLU B O   1 
ATOM   3343  C  CB  . GLU B 1 144 ? 32.414  -14.100 26.945  1.00 32.19  ? 144 GLU B CB  1 
ATOM   3344  C  CG  . GLU B 1 144 ? 31.606  -13.022 26.218  1.00 35.24  ? 144 GLU B CG  1 
ATOM   3345  C  CD  . GLU B 1 144 ? 30.388  -13.596 25.537  1.00 36.52  ? 144 GLU B CD  1 
ATOM   3346  O  OE1 . GLU B 1 144 ? 30.265  -14.840 25.294  1.00 35.14  ? 144 GLU B OE1 1 
ATOM   3347  O  OE2 . GLU B 1 144 ? 29.540  -12.715 25.349  1.00 38.63  ? 144 GLU B OE2 1 
ATOM   3348  N  N   . ARG B 1 145 ? 32.241  -15.701 30.346  1.00 23.72  ? 145 ARG B N   1 
ATOM   3349  C  CA  . ARG B 1 145 ? 32.738  -16.804 31.144  1.00 25.83  ? 145 ARG B CA  1 
ATOM   3350  C  C   . ARG B 1 145 ? 31.776  -17.988 31.172  1.00 25.51  ? 145 ARG B C   1 
ATOM   3351  O  O   . ARG B 1 145 ? 30.588  -17.875 30.831  1.00 23.18  ? 145 ARG B O   1 
ATOM   3352  C  CB  . ARG B 1 145 ? 33.142  -16.348 32.538  1.00 28.88  ? 145 ARG B CB  1 
ATOM   3353  C  CG  . ARG B 1 145 ? 34.334  -15.420 32.370  1.00 26.64  ? 145 ARG B CG  1 
ATOM   3354  C  CD  . ARG B 1 145 ? 34.813  -14.847 33.673  1.00 27.86  ? 145 ARG B CD  1 
ATOM   3355  N  NE  . ARG B 1 145 ? 35.808  -13.772 33.496  1.00 32.17  ? 145 ARG B NE  1 
ATOM   3356  C  CZ  . ARG B 1 145 ? 37.122  -13.985 33.402  1.00 33.78  ? 145 ARG B CZ  1 
ATOM   3357  N  NH1 . ARG B 1 145 ? 38.002  -13.041 33.502  1.00 34.99  ? 145 ARG B NH1 1 
ATOM   3358  N  NH2 . ARG B 1 145 ? 37.616  -15.197 33.359  1.00 36.34  ? 145 ARG B NH2 1 
ATOM   3359  N  N   . ASP B 1 146 ? 32.391  -19.168 31.364  1.00 23.18  ? 146 ASP B N   1 
ATOM   3360  C  CA  . ASP B 1 146 ? 31.657  -20.406 31.507  1.00 28.70  ? 146 ASP B CA  1 
ATOM   3361  C  C   . ASP B 1 146 ? 31.535  -20.753 32.982  1.00 25.20  ? 146 ASP B C   1 
ATOM   3362  O  O   . ASP B 1 146 ? 31.916  -19.966 33.838  1.00 24.69  ? 146 ASP B O   1 
ATOM   3363  C  CB  . ASP B 1 146 ? 32.214  -21.504 30.609  1.00 30.98  ? 146 ASP B CB  1 
ATOM   3364  C  CG  . ASP B 1 146 ? 33.638  -21.878 30.882  1.00 25.82  ? 146 ASP B CG  1 
ATOM   3365  O  OD1 . ASP B 1 146 ? 34.051  -21.682 32.038  1.00 24.87  ? 146 ASP B OD1 1 
ATOM   3366  O  OD2 . ASP B 1 146 ? 34.279  -22.368 29.934  1.00 26.58  ? 146 ASP B OD2 1 
ATOM   3367  N  N   . MET B 1 147 ? 30.998  -21.944 33.221  1.00 26.77  ? 147 MET B N   1 
ATOM   3368  C  CA  . MET B 1 147 ? 30.708  -22.427 34.559  1.00 32.32  ? 147 MET B CA  1 
ATOM   3369  C  C   . MET B 1 147 ? 32.021  -22.608 35.350  1.00 34.37  ? 147 MET B C   1 
ATOM   3370  O  O   . MET B 1 147 ? 32.014  -22.553 36.551  1.00 27.27  ? 147 MET B O   1 
ATOM   3371  C  CB  . MET B 1 147 ? 29.877  -23.725 34.415  1.00 29.83  ? 147 MET B CB  1 
ATOM   3372  C  CG  . MET B 1 147 ? 29.139  -24.152 35.657  1.00 31.79  ? 147 MET B CG  1 
ATOM   3373  S  SD  . MET B 1 147 ? 27.955  -22.966 36.332  1.00 33.43  ? 147 MET B SD  1 
ATOM   3374  C  CE  . MET B 1 147 ? 26.438  -23.285 35.421  1.00 37.97  ? 147 MET B CE  1 
ATOM   3375  N  N   . LEU B 1 148 ? 33.155  -22.859 34.690  1.00 26.56  ? 148 LEU B N   1 
ATOM   3376  C  CA  . LEU B 1 148 ? 34.402  -22.995 35.395  1.00 26.02  ? 148 LEU B CA  1 
ATOM   3377  C  C   . LEU B 1 148 ? 35.058  -21.639 35.620  1.00 23.36  ? 148 LEU B C   1 
ATOM   3378  O  O   . LEU B 1 148 ? 36.126  -21.559 36.211  1.00 24.38  ? 148 LEU B O   1 
ATOM   3379  C  CB  . LEU B 1 148 ? 35.294  -23.870 34.512  1.00 28.89  ? 148 LEU B CB  1 
ATOM   3380  C  CG  . LEU B 1 148 ? 34.801  -25.292 34.211  1.00 30.92  ? 148 LEU B CG  1 
ATOM   3381  C  CD1 . LEU B 1 148 ? 35.824  -26.042 33.406  1.00 29.67  ? 148 LEU B CD1 1 
ATOM   3382  C  CD2 . LEU B 1 148 ? 34.505  -26.068 35.462  1.00 35.25  ? 148 LEU B CD2 1 
ATOM   3383  N  N   . GLY B 1 149 ? 34.475  -20.553 35.118  1.00 24.60  ? 149 GLY B N   1 
ATOM   3384  C  CA  . GLY B 1 149 ? 34.991  -19.202 35.394  1.00 22.39  ? 149 GLY B CA  1 
ATOM   3385  C  C   . GLY B 1 149 ? 35.991  -18.681 34.362  1.00 23.15  ? 149 GLY B C   1 
ATOM   3386  O  O   . GLY B 1 149 ? 36.626  -17.663 34.608  1.00 23.59  ? 149 GLY B O   1 
ATOM   3387  N  N   . PHE B 1 150 ? 36.150  -19.415 33.248  1.00 22.77  ? 150 PHE B N   1 
ATOM   3388  C  CA  . PHE B 1 150 ? 37.083  -19.089 32.185  1.00 25.98  ? 150 PHE B CA  1 
ATOM   3389  C  C   . PHE B 1 150 ? 36.330  -18.474 31.025  1.00 23.78  ? 150 PHE B C   1 
ATOM   3390  O  O   . PHE B 1 150 ? 35.232  -18.903 30.748  1.00 25.42  ? 150 PHE B O   1 
ATOM   3391  C  CB  . PHE B 1 150 ? 37.895  -20.315 31.720  1.00 26.73  ? 150 PHE B CB  1 
ATOM   3392  C  CG  . PHE B 1 150 ? 39.071  -20.589 32.624  1.00 25.20  ? 150 PHE B CG  1 
ATOM   3393  C  CD1 . PHE B 1 150 ? 38.871  -21.059 33.905  1.00 26.54  ? 150 PHE B CD1 1 
ATOM   3394  C  CD2 . PHE B 1 150 ? 40.364  -20.269 32.238  1.00 28.45  ? 150 PHE B CD2 1 
ATOM   3395  C  CE1 . PHE B 1 150 ? 39.935  -21.271 34.767  1.00 25.46  ? 150 PHE B CE1 1 
ATOM   3396  C  CE2 . PHE B 1 150 ? 41.449  -20.489 33.093  1.00 28.12  ? 150 PHE B CE2 1 
ATOM   3397  C  CZ  . PHE B 1 150 ? 41.231  -21.002 34.360  1.00 27.44  ? 150 PHE B CZ  1 
ATOM   3398  N  N   . VAL B 1 151 ? 36.925  -17.473 30.344  1.00 24.19  ? 151 VAL B N   1 
ATOM   3399  C  CA  . VAL B 1 151 ? 36.334  -16.936 29.113  1.00 21.69  ? 151 VAL B CA  1 
ATOM   3400  C  C   . VAL B 1 151 ? 36.266  -18.074 28.103  1.00 22.96  ? 151 VAL B C   1 
ATOM   3401  O  O   . VAL B 1 151 ? 37.211  -18.862 27.999  1.00 26.11  ? 151 VAL B O   1 
ATOM   3402  C  CB  . VAL B 1 151 ? 37.163  -15.761 28.586  1.00 21.67  ? 151 VAL B CB  1 
ATOM   3403  C  CG1 . VAL B 1 151 ? 36.584  -15.237 27.329  1.00 21.82  ? 151 VAL B CG1 1 
ATOM   3404  C  CG2 . VAL B 1 151 ? 37.355  -14.640 29.603  1.00 24.09  ? 151 VAL B CG2 1 
ATOM   3405  N  N   . ASP B 1 152 ? 35.151  -18.180 27.384  1.00 23.62  ? 152 ASP B N   1 
ATOM   3406  C  CA  . ASP B 1 152 ? 34.872  -19.340 26.549  1.00 23.74  ? 152 ASP B CA  1 
ATOM   3407  C  C   . ASP B 1 152 ? 34.418  -18.824 25.196  1.00 24.84  ? 152 ASP B C   1 
ATOM   3408  O  O   . ASP B 1 152 ? 33.382  -18.181 25.094  1.00 24.33  ? 152 ASP B O   1 
ATOM   3409  C  CB  . ASP B 1 152 ? 33.821  -20.209 27.197  1.00 27.32  ? 152 ASP B CB  1 
ATOM   3410  C  CG  . ASP B 1 152 ? 33.676  -21.654 26.720  1.00 36.67  ? 152 ASP B CG  1 
ATOM   3411  O  OD1 . ASP B 1 152 ? 33.798  -21.827 25.504  1.00 31.65  ? 152 ASP B OD1 1 
ATOM   3412  O  OD2 . ASP B 1 152 ? 33.355  -22.603 27.579  1.00 40.96  ? 152 ASP B OD2 1 
ATOM   3413  N  N   . GLY B 1 153 ? 35.252  -19.089 24.188  1.00 23.83  ? 153 GLY B N   1 
ATOM   3414  C  CA  . GLY B 1 153 ? 34.979  -18.751 22.802  1.00 27.56  ? 153 GLY B CA  1 
ATOM   3415  C  C   . GLY B 1 153 ? 36.099  -17.955 22.115  1.00 24.97  ? 153 GLY B C   1 
ATOM   3416  O  O   . GLY B 1 153 ? 36.009  -17.712 20.931  1.00 25.80  ? 153 GLY B O   1 
ATOM   3417  N  N   . THR B 1 154 ? 37.144  -17.570 22.850  1.00 28.23  ? 154 THR B N   1 
ATOM   3418  C  CA  . THR B 1 154 ? 38.189  -16.642 22.446  1.00 29.22  ? 154 THR B CA  1 
ATOM   3419  C  C   . THR B 1 154 ? 38.842  -17.043 21.124  1.00 28.75  ? 154 THR B C   1 
ATOM   3420  O  O   . THR B 1 154 ? 39.037  -16.222 20.257  1.00 26.63  ? 154 THR B O   1 
ATOM   3421  C  CB  . THR B 1 154 ? 39.239  -16.644 23.547  1.00 31.21  ? 154 THR B CB  1 
ATOM   3422  O  OG1 . THR B 1 154 ? 38.615  -16.438 24.800  1.00 27.88  ? 154 THR B OG1 1 
ATOM   3423  C  CG2 . THR B 1 154 ? 40.247  -15.552 23.295  1.00 35.97  ? 154 THR B CG2 1 
ATOM   3424  N  N   . GLU B 1 155 ? 39.183  -18.318 20.965  1.00 25.89  ? 155 GLU B N   1 
ATOM   3425  C  CA  . GLU B 1 155 ? 39.909  -18.733 19.775  1.00 29.03  ? 155 GLU B CA  1 
ATOM   3426  C  C   . GLU B 1 155 ? 38.963  -19.338 18.739  1.00 32.83  ? 155 GLU B C   1 
ATOM   3427  O  O   . GLU B 1 155 ? 39.404  -20.025 17.816  1.00 31.91  ? 155 GLU B O   1 
ATOM   3428  C  CB  . GLU B 1 155 ? 41.071  -19.706 20.044  1.00 31.46  ? 155 GLU B CB  1 
ATOM   3429  C  CG  . GLU B 1 155 ? 42.201  -19.046 20.840  1.00 35.13  ? 155 GLU B CG  1 
ATOM   3430  C  CD  . GLU B 1 155 ? 42.946  -17.897 20.170  1.00 31.76  ? 155 GLU B CD  1 
ATOM   3431  O  OE1 . GLU B 1 155 ? 43.280  -18.189 19.060  1.00 29.44  ? 155 GLU B OE1 1 
ATOM   3432  O  OE2 . GLU B 1 155 ? 43.268  -16.836 20.692  1.00 38.54  ? 155 GLU B OE2 1 
ATOM   3433  N  N   . ASN B 1 156 ? 37.661  -19.074 18.810  1.00 28.65  ? 156 ASN B N   1 
ATOM   3434  C  CA  . ASN B 1 156 ? 36.832  -19.474 17.689  1.00 30.14  ? 156 ASN B CA  1 
ATOM   3435  C  C   . ASN B 1 156 ? 37.289  -18.741 16.419  1.00 33.79  ? 156 ASN B C   1 
ATOM   3436  O  O   . ASN B 1 156 ? 37.553  -17.539 16.450  1.00 29.46  ? 156 ASN B O   1 
ATOM   3437  C  CB  . ASN B 1 156 ? 35.363  -19.099 17.879  1.00 26.74  ? 156 ASN B CB  1 
ATOM   3438  C  CG  . ASN B 1 156 ? 34.591  -20.200 18.533  1.00 29.69  ? 156 ASN B CG  1 
ATOM   3439  O  OD1 . ASN B 1 156 ? 34.832  -21.393 18.335  1.00 32.25  ? 156 ASN B OD1 1 
ATOM   3440  N  ND2 . ASN B 1 156 ? 33.671  -19.821 19.376  1.00 31.09  ? 156 ASN B ND2 1 
ATOM   3441  N  N   . PRO B 1 157 ? 37.268  -19.371 15.230  1.00 32.17  ? 157 PRO B N   1 
ATOM   3442  C  CA  . PRO B 1 157 ? 37.493  -18.630 14.001  1.00 34.28  ? 157 PRO B CA  1 
ATOM   3443  C  C   . PRO B 1 157 ? 36.391  -17.623 13.717  1.00 35.31  ? 157 PRO B C   1 
ATOM   3444  O  O   . PRO B 1 157 ? 35.278  -17.778 14.210  1.00 37.83  ? 157 PRO B O   1 
ATOM   3445  C  CB  . PRO B 1 157 ? 37.531  -19.730 13.002  1.00 33.99  ? 157 PRO B CB  1 
ATOM   3446  C  CG  . PRO B 1 157 ? 36.623  -20.744 13.557  1.00 33.84  ? 157 PRO B CG  1 
ATOM   3447  C  CD  . PRO B 1 157 ? 36.898  -20.767 15.020  1.00 35.24  ? 157 PRO B CD  1 
ATOM   3448  N  N   . THR B 1 158 ? 36.727  -16.592 12.948  1.00 36.79  ? 158 THR B N   1 
ATOM   3449  C  CA  . THR B 1 158 ? 35.743  -15.600 12.528  1.00 40.83  ? 158 THR B CA  1 
ATOM   3450  C  C   . THR B 1 158 ? 35.844  -15.293 11.020  1.00 41.20  ? 158 THR B C   1 
ATOM   3451  O  O   . THR B 1 158 ? 36.798  -15.658 10.342  1.00 33.08  ? 158 THR B O   1 
ATOM   3452  C  CB  . THR B 1 158 ? 35.876  -14.313 13.346  1.00 39.46  ? 158 THR B CB  1 
ATOM   3453  O  OG1 . THR B 1 158 ? 37.132  -13.765 12.987  1.00 37.07  ? 158 THR B OG1 1 
ATOM   3454  C  CG2 . THR B 1 158 ? 35.743  -14.494 14.850  1.00 40.95  ? 158 THR B CG2 1 
ATOM   3455  N  N   . GLY B 1 159 ? 34.805  -14.633 10.485  1.00 43.11  ? 159 GLY B N   1 
ATOM   3456  C  CA  . GLY B 1 159 ? 34.747  -14.270 9.085   1.00 40.04  ? 159 GLY B CA  1 
ATOM   3457  C  C   . GLY B 1 159 ? 35.031  -15.451 8.162   1.00 42.74  ? 159 GLY B C   1 
ATOM   3458  O  O   . GLY B 1 159 ? 34.357  -16.474 8.208   1.00 50.11  ? 159 GLY B O   1 
ATOM   3459  N  N   . ALA B 1 160 ? 36.004  -15.273 7.277   1.00 41.22  ? 160 ALA B N   1 
ATOM   3460  C  CA  . ALA B 1 160 ? 36.189  -16.193 6.178   1.00 42.33  ? 160 ALA B CA  1 
ATOM   3461  C  C   . ALA B 1 160 ? 36.849  -17.451 6.716   1.00 40.21  ? 160 ALA B C   1 
ATOM   3462  O  O   . ALA B 1 160 ? 36.673  -18.519 6.156   1.00 40.24  ? 160 ALA B O   1 
ATOM   3463  C  CB  . ALA B 1 160 ? 37.038  -15.566 5.102   1.00 49.54  ? 160 ALA B CB  1 
ATOM   3464  N  N   . ALA B 1 161 ? 37.607  -17.322 7.813   1.00 47.11  ? 161 ALA B N   1 
ATOM   3465  C  CA  . ALA B 1 161 ? 38.221  -18.503 8.419   1.00 48.02  ? 161 ALA B CA  1 
ATOM   3466  C  C   . ALA B 1 161 ? 37.116  -19.434 8.930   1.00 44.85  ? 161 ALA B C   1 
ATOM   3467  O  O   . ALA B 1 161 ? 37.208  -20.673 8.829   1.00 42.58  ? 161 ALA B O   1 
ATOM   3468  C  CB  . ALA B 1 161 ? 39.194  -18.129 9.538   1.00 47.54  ? 161 ALA B CB  1 
ATOM   3469  N  N   . ALA B 1 162 ? 36.071  -18.808 9.495   1.00 40.77  ? 162 ALA B N   1 
ATOM   3470  C  CA  . ALA B 1 162 ? 34.943  -19.556 10.016  1.00 39.86  ? 162 ALA B CA  1 
ATOM   3471  C  C   . ALA B 1 162 ? 34.155  -20.229 8.879   1.00 35.92  ? 162 ALA B C   1 
ATOM   3472  O  O   . ALA B 1 162 ? 33.887  -21.417 9.020   1.00 29.05  ? 162 ALA B O   1 
ATOM   3473  C  CB  . ALA B 1 162 ? 34.118  -18.628 10.896  1.00 39.25  ? 162 ALA B CB  1 
ATOM   3474  N  N   . ARG B 1 163 ? 33.810  -19.499 7.786   1.00 36.45  ? 163 ARG B N   1 
ATOM   3475  C  CA  . ARG B 1 163 ? 33.156  -20.103 6.612   1.00 43.96  ? 163 ARG B CA  1 
ATOM   3476  C  C   . ARG B 1 163 ? 33.978  -21.311 6.133   1.00 34.75  ? 163 ARG B C   1 
ATOM   3477  O  O   . ARG B 1 163 ? 33.401  -22.356 5.859   1.00 27.73  ? 163 ARG B O   1 
ATOM   3478  C  CB  . ARG B 1 163 ? 32.834  -19.144 5.437   1.00 51.46  ? 163 ARG B CB  1 
ATOM   3479  C  CG  . ARG B 1 163 ? 32.124  -17.829 5.783   1.00 62.85  ? 163 ARG B CG  1 
ATOM   3480  C  CD  . ARG B 1 163 ? 31.819  -16.777 4.679   1.00 63.15  ? 163 ARG B CD  1 
ATOM   3481  N  NE  . ARG B 1 163 ? 30.732  -17.273 3.817   1.00 54.41  ? 163 ARG B NE  1 
ATOM   3482  N  N   . ARG B 1 164 ? 35.316  -21.187 6.053   1.00 33.27  ? 164 ARG B N   1 
ATOM   3483  C  CA  . ARG B 1 164 ? 36.192  -22.256 5.552   1.00 39.87  ? 164 ARG B CA  1 
ATOM   3484  C  C   . ARG B 1 164 ? 36.089  -23.455 6.522   1.00 40.93  ? 164 ARG B C   1 
ATOM   3485  O  O   . ARG B 1 164 ? 36.031  -24.627 6.118   1.00 44.10  ? 164 ARG B O   1 
ATOM   3486  C  CB  . ARG B 1 164 ? 37.624  -21.817 5.106   1.00 27.24  ? 164 ARG B CB  1 
ATOM   3487  N  N   . ALA B 1 165 ? 35.992  -23.189 7.832   1.00 40.86  ? 165 ALA B N   1 
ATOM   3488  C  CA  . ALA B 1 165 ? 36.096  -24.271 8.805   1.00 39.78  ? 165 ALA B CA  1 
ATOM   3489  C  C   . ALA B 1 165 ? 34.779  -25.041 9.010   1.00 36.03  ? 165 ALA B C   1 
ATOM   3490  O  O   . ALA B 1 165 ? 34.770  -26.208 9.426   1.00 35.26  ? 165 ALA B O   1 
ATOM   3491  C  CB  . ALA B 1 165 ? 36.593  -23.669 10.107  1.00 40.70  ? 165 ALA B CB  1 
ATOM   3492  N  N   . VAL B 1 166 ? 33.643  -24.368 8.772   1.00 33.30  ? 166 VAL B N   1 
ATOM   3493  C  CA  . VAL B 1 166 ? 32.359  -24.907 9.204   1.00 40.54  ? 166 VAL B CA  1 
ATOM   3494  C  C   . VAL B 1 166 ? 31.469  -25.369 8.032   1.00 38.37  ? 166 VAL B C   1 
ATOM   3495  O  O   . VAL B 1 166 ? 30.667  -26.292 8.240   1.00 38.22  ? 166 VAL B O   1 
ATOM   3496  C  CB  . VAL B 1 166 ? 31.688  -23.774 10.008  1.00 41.96  ? 166 VAL B CB  1 
ATOM   3497  C  CG1 . VAL B 1 166 ? 30.224  -24.058 10.287  1.00 43.75  ? 166 VAL B CG1 1 
ATOM   3498  C  CG2 . VAL B 1 166 ? 32.425  -23.461 11.300  1.00 40.07  ? 166 VAL B CG2 1 
ATOM   3499  N  N   . LEU B 1 167 ? 31.570  -24.763 6.823   1.00 28.82  ? 167 LEU B N   1 
ATOM   3500  C  CA  . LEU B 1 167 ? 30.595  -25.051 5.780   1.00 29.96  ? 167 LEU B CA  1 
ATOM   3501  C  C   . LEU B 1 167 ? 31.103  -26.070 4.759   1.00 32.67  ? 167 LEU B C   1 
ATOM   3502  O  O   . LEU B 1 167 ? 32.215  -25.958 4.258   1.00 27.77  ? 167 LEU B O   1 
ATOM   3503  C  CB  . LEU B 1 167 ? 30.172  -23.755 5.107   1.00 32.98  ? 167 LEU B CB  1 
ATOM   3504  C  CG  . LEU B 1 167 ? 29.560  -22.729 6.067   1.00 36.87  ? 167 LEU B CG  1 
ATOM   3505  C  CD1 . LEU B 1 167 ? 29.249  -21.411 5.430   1.00 40.84  ? 167 LEU B CD1 1 
ATOM   3506  C  CD2 . LEU B 1 167 ? 28.311  -23.327 6.692   1.00 36.85  ? 167 LEU B CD2 1 
ATOM   3507  N  N   . VAL B 1 168 ? 30.250  -27.080 4.479   1.00 30.63  ? 168 VAL B N   1 
ATOM   3508  C  CA  . VAL B 1 168 ? 30.521  -28.065 3.474   1.00 28.84  ? 168 VAL B CA  1 
ATOM   3509  C  C   . VAL B 1 168 ? 30.664  -27.320 2.161   1.00 38.46  ? 168 VAL B C   1 
ATOM   3510  O  O   . VAL B 1 168 ? 29.854  -26.443 1.876   1.00 41.54  ? 168 VAL B O   1 
ATOM   3511  C  CB  . VAL B 1 168 ? 29.381  -29.071 3.378   1.00 31.66  ? 168 VAL B CB  1 
ATOM   3512  C  CG1 . VAL B 1 168 ? 29.551  -30.007 2.183   1.00 32.73  ? 168 VAL B CG1 1 
ATOM   3513  C  CG2 . VAL B 1 168 ? 29.244  -29.887 4.639   1.00 36.26  ? 168 VAL B CG2 1 
ATOM   3514  N  N   . GLY B 1 169 ? 31.686  -27.674 1.372   1.00 40.92  ? 169 GLY B N   1 
ATOM   3515  C  CA  . GLY B 1 169 ? 31.895  -27.048 0.072   1.00 40.98  ? 169 GLY B CA  1 
ATOM   3516  C  C   . GLY B 1 169 ? 31.835  -28.085 -1.053  1.00 41.00  ? 169 GLY B C   1 
ATOM   3517  O  O   . GLY B 1 169 ? 31.024  -29.053 -1.096  1.00 37.79  ? 169 GLY B O   1 
ATOM   3518  N  N   . ALA B 1 170 ? 32.763  -27.857 -1.975  1.00 54.13  ? 170 ALA B N   1 
ATOM   3519  C  CA  . ALA B 1 170 ? 32.822  -28.585 -3.230  1.00 51.52  ? 170 ALA B CA  1 
ATOM   3520  C  C   . ALA B 1 170 ? 33.183  -30.051 -2.990  1.00 48.99  ? 170 ALA B C   1 
ATOM   3521  O  O   . ALA B 1 170 ? 32.915  -30.889 -3.839  1.00 59.64  ? 170 ALA B O   1 
ATOM   3522  C  CB  . ALA B 1 170 ? 33.829  -27.854 -4.088  1.00 49.25  ? 170 ALA B CB  1 
ATOM   3523  N  N   . GLU B 1 171 ? 33.694  -30.397 -1.795  1.00 42.78  ? 171 GLU B N   1 
ATOM   3524  C  CA  . GLU B 1 171 ? 34.033  -31.791 -1.510  1.00 40.28  ? 171 GLU B CA  1 
ATOM   3525  C  C   . GLU B 1 171 ? 32.786  -32.653 -1.391  1.00 40.43  ? 171 GLU B C   1 
ATOM   3526  O  O   . GLU B 1 171 ? 32.915  -33.866 -1.321  1.00 47.41  ? 171 GLU B O   1 
ATOM   3527  C  CB  . GLU B 1 171 ? 34.949  -31.935 -0.285  1.00 40.43  ? 171 GLU B CB  1 
ATOM   3528  C  CG  . GLU B 1 171 ? 34.288  -31.705 1.074   1.00 40.30  ? 171 GLU B CG  1 
ATOM   3529  C  CD  . GLU B 1 171 ? 33.898  -30.303 1.514   1.00 44.11  ? 171 GLU B CD  1 
ATOM   3530  O  OE1 . GLU B 1 171 ? 34.175  -29.352 0.735   1.00 36.09  ? 171 GLU B OE1 1 
ATOM   3531  O  OE2 . GLU B 1 171 ? 33.337  -30.138 2.653   1.00 44.43  ? 171 GLU B OE2 1 
ATOM   3532  N  N   . ASP B 1 172 ? 31.592  -32.056 -1.269  1.00 43.23  ? 172 ASP B N   1 
ATOM   3533  C  CA  . ASP B 1 172 ? 30.356  -32.843 -1.141  1.00 48.71  ? 172 ASP B CA  1 
ATOM   3534  C  C   . ASP B 1 172 ? 29.232  -31.967 -1.659  1.00 50.00  ? 172 ASP B C   1 
ATOM   3535  O  O   . ASP B 1 172 ? 28.370  -31.489 -0.923  1.00 39.18  ? 172 ASP B O   1 
ATOM   3536  C  CB  . ASP B 1 172 ? 30.076  -33.420 0.252   1.00 45.73  ? 172 ASP B CB  1 
ATOM   3537  C  CG  . ASP B 1 172 ? 28.940  -34.441 0.327   1.00 45.10  ? 172 ASP B CG  1 
ATOM   3538  O  OD1 . ASP B 1 172 ? 28.393  -34.810 -0.717  1.00 45.57  ? 172 ASP B OD1 1 
ATOM   3539  O  OD2 . ASP B 1 172 ? 28.560  -34.867 1.417   1.00 40.78  ? 172 ASP B OD2 1 
ATOM   3540  N  N   . PRO B 1 173 ? 29.250  -31.716 -2.979  1.00 54.89  ? 173 PRO B N   1 
ATOM   3541  C  CA  . PRO B 1 173 ? 28.640  -30.479 -3.493  1.00 50.86  ? 173 PRO B CA  1 
ATOM   3542  C  C   . PRO B 1 173 ? 27.121  -30.526 -3.450  1.00 38.27  ? 173 PRO B C   1 
ATOM   3543  O  O   . PRO B 1 173 ? 26.471  -29.487 -3.446  1.00 38.02  ? 173 PRO B O   1 
ATOM   3544  C  CB  . PRO B 1 173 ? 29.250  -30.298 -4.877  1.00 48.97  ? 173 PRO B CB  1 
ATOM   3545  C  CG  . PRO B 1 173 ? 30.104  -31.561 -5.120  1.00 45.40  ? 173 PRO B CG  1 
ATOM   3546  C  CD  . PRO B 1 173 ? 29.914  -32.564 -3.987  1.00 47.43  ? 173 PRO B CD  1 
ATOM   3547  N  N   . ALA B 1 174 ? 26.546  -31.726 -3.384  1.00 35.07  ? 174 ALA B N   1 
ATOM   3548  C  CA  . ALA B 1 174 ? 25.110  -31.784 -3.198  1.00 41.72  ? 174 ALA B CA  1 
ATOM   3549  C  C   . ALA B 1 174 ? 24.686  -31.129 -1.885  1.00 41.44  ? 174 ALA B C   1 
ATOM   3550  O  O   . ALA B 1 174 ? 23.526  -30.849 -1.728  1.00 38.80  ? 174 ALA B O   1 
ATOM   3551  C  CB  . ALA B 1 174 ? 24.677  -33.233 -3.199  1.00 48.91  ? 174 ALA B CB  1 
ATOM   3552  N  N   . PHE B 1 175 ? 25.580  -31.053 -0.882  1.00 41.72  ? 175 PHE B N   1 
ATOM   3553  C  CA  . PHE B 1 175 ? 25.226  -30.622 0.469   1.00 39.88  ? 175 PHE B CA  1 
ATOM   3554  C  C   . PHE B 1 175 ? 26.005  -29.381 0.875   1.00 43.08  ? 175 PHE B C   1 
ATOM   3555  O  O   . PHE B 1 175 ? 26.087  -29.055 2.045   1.00 47.56  ? 175 PHE B O   1 
ATOM   3556  C  CB  . PHE B 1 175 ? 25.496  -31.796 1.398   1.00 34.07  ? 175 PHE B CB  1 
ATOM   3557  C  CG  . PHE B 1 175 ? 24.520  -32.933 1.152   1.00 36.54  ? 175 PHE B CG  1 
ATOM   3558  C  CD1 . PHE B 1 175 ? 23.179  -32.779 1.469   1.00 41.91  ? 175 PHE B CD1 1 
ATOM   3559  C  CD2 . PHE B 1 175 ? 24.953  -34.137 0.599   1.00 41.42  ? 175 PHE B CD2 1 
ATOM   3560  C  CE1 . PHE B 1 175 ? 22.294  -33.810 1.266   1.00 45.31  ? 175 PHE B CE1 1 
ATOM   3561  C  CE2 . PHE B 1 175 ? 24.063  -35.154 0.353   1.00 42.86  ? 175 PHE B CE2 1 
ATOM   3562  C  CZ  . PHE B 1 175 ? 22.741  -35.002 0.721   1.00 49.68  ? 175 PHE B CZ  1 
ATOM   3563  N  N   . ALA B 1 176 ? 26.598  -28.696 -0.098  1.00 41.52  ? 176 ALA B N   1 
ATOM   3564  C  CA  . ALA B 1 176 ? 27.307  -27.479 0.208   1.00 43.67  ? 176 ALA B CA  1 
ATOM   3565  C  C   . ALA B 1 176 ? 26.345  -26.541 0.944   1.00 44.66  ? 176 ALA B C   1 
ATOM   3566  O  O   . ALA B 1 176 ? 25.141  -26.462 0.592   1.00 37.88  ? 176 ALA B O   1 
ATOM   3567  C  CB  . ALA B 1 176 ? 27.830  -26.878 -1.067  1.00 41.25  ? 176 ALA B CB  1 
ATOM   3568  N  N   . GLY B 1 177 ? 26.935  -25.857 1.958   1.00 38.98  ? 177 GLY B N   1 
ATOM   3569  C  CA  . GLY B 1 177 ? 26.257  -24.874 2.794   1.00 43.39  ? 177 GLY B CA  1 
ATOM   3570  C  C   . GLY B 1 177 ? 25.769  -25.483 4.114   1.00 39.15  ? 177 GLY B C   1 
ATOM   3571  O  O   . GLY B 1 177 ? 25.202  -24.807 4.996   1.00 40.38  ? 177 GLY B O   1 
ATOM   3572  N  N   . GLY B 1 178 ? 25.921  -26.805 4.193   1.00 31.97  ? 178 GLY B N   1 
ATOM   3573  C  CA  . GLY B 1 178 ? 25.636  -27.547 5.413   1.00 34.32  ? 178 GLY B CA  1 
ATOM   3574  C  C   . GLY B 1 178 ? 26.819  -27.534 6.388   1.00 30.81  ? 178 GLY B C   1 
ATOM   3575  O  O   . GLY B 1 178 ? 27.869  -26.959 6.102   1.00 29.69  ? 178 GLY B O   1 
ATOM   3576  N  N   . SER B 1 179 ? 26.602  -28.165 7.545   1.00 30.55  ? 179 SER B N   1 
ATOM   3577  C  CA  . SER B 1 179 ? 27.626  -28.288 8.568   1.00 25.48  ? 179 SER B CA  1 
ATOM   3578  C  C   . SER B 1 179 ? 27.282  -29.500 9.411   1.00 27.23  ? 179 SER B C   1 
ATOM   3579  O  O   . SER B 1 179 ? 26.221  -30.116 9.237   1.00 26.33  ? 179 SER B O   1 
ATOM   3580  C  CB  . SER B 1 179 ? 27.763  -27.046 9.394   1.00 25.65  ? 179 SER B CB  1 
ATOM   3581  O  OG  . SER B 1 179 ? 28.952  -27.049 10.176  1.00 24.61  ? 179 SER B OG  1 
ATOM   3582  N  N   . TYR B 1 180 ? 28.278  -29.933 10.202  1.00 32.47  ? 180 TYR B N   1 
ATOM   3583  C  CA  . TYR B 1 180 ? 28.090  -31.068 11.104  1.00 31.47  ? 180 TYR B CA  1 
ATOM   3584  C  C   . TYR B 1 180 ? 28.187  -30.532 12.534  1.00 31.85  ? 180 TYR B C   1 
ATOM   3585  O  O   . TYR B 1 180 ? 29.209  -29.879 12.893  1.00 34.15  ? 180 TYR B O   1 
ATOM   3586  C  CB  . TYR B 1 180 ? 29.167  -32.136 10.866  1.00 32.49  ? 180 TYR B CB  1 
ATOM   3587  C  CG  . TYR B 1 180 ? 29.058  -32.826 9.526   1.00 27.72  ? 180 TYR B CG  1 
ATOM   3588  C  CD1 . TYR B 1 180 ? 29.665  -32.298 8.397   1.00 30.82  ? 180 TYR B CD1 1 
ATOM   3589  C  CD2 . TYR B 1 180 ? 28.323  -33.983 9.391   1.00 30.23  ? 180 TYR B CD2 1 
ATOM   3590  C  CE1 . TYR B 1 180 ? 29.488  -32.890 7.150   1.00 31.59  ? 180 TYR B CE1 1 
ATOM   3591  C  CE2 . TYR B 1 180 ? 28.156  -34.590 8.158   1.00 32.50  ? 180 TYR B CE2 1 
ATOM   3592  C  CZ  . TYR B 1 180 ? 28.728  -34.047 7.021   1.00 29.89  ? 180 TYR B CZ  1 
ATOM   3593  O  OH  . TYR B 1 180 ? 28.522  -34.698 5.817   1.00 26.48  ? 180 TYR B OH  1 
ATOM   3594  N  N   . ALA B 1 181 ? 27.141  -30.850 13.331  1.00 27.10  ? 181 ALA B N   1 
ATOM   3595  C  CA  . ALA B 1 181 ? 27.120  -30.458 14.724  1.00 28.07  ? 181 ALA B CA  1 
ATOM   3596  C  C   . ALA B 1 181 ? 27.328  -31.671 15.621  1.00 25.58  ? 181 ALA B C   1 
ATOM   3597  O  O   . ALA B 1 181 ? 26.637  -32.682 15.456  1.00 23.55  ? 181 ALA B O   1 
ATOM   3598  C  CB  . ALA B 1 181 ? 25.826  -29.752 15.024  1.00 26.89  ? 181 ALA B CB  1 
ATOM   3599  N  N   . VAL B 1 182 ? 28.219  -31.506 16.608  1.00 24.59  ? 182 VAL B N   1 
ATOM   3600  C  CA  . VAL B 1 182 ? 28.371  -32.470 17.692  1.00 26.70  ? 182 VAL B CA  1 
ATOM   3601  C  C   . VAL B 1 182 ? 27.950  -31.780 18.976  1.00 25.72  ? 182 VAL B C   1 
ATOM   3602  O  O   . VAL B 1 182 ? 28.443  -30.714 19.255  1.00 24.03  ? 182 VAL B O   1 
ATOM   3603  C  CB  . VAL B 1 182 ? 29.823  -33.002 17.813  1.00 30.83  ? 182 VAL B CB  1 
ATOM   3604  C  CG1 . VAL B 1 182 ? 29.995  -33.895 19.009  1.00 30.97  ? 182 VAL B CG1 1 
ATOM   3605  C  CG2 . VAL B 1 182 ? 30.286  -33.767 16.573  1.00 31.87  ? 182 VAL B CG2 1 
ATOM   3606  N  N   . VAL B 1 183 ? 27.113  -32.456 19.772  1.00 26.10  ? 183 VAL B N   1 
ATOM   3607  C  CA  . VAL B 1 183 ? 26.694  -31.981 21.060  1.00 23.81  ? 183 VAL B CA  1 
ATOM   3608  C  C   . VAL B 1 183 ? 27.127  -32.985 22.116  1.00 23.89  ? 183 VAL B C   1 
ATOM   3609  O  O   . VAL B 1 183 ? 27.100  -34.194 21.899  1.00 28.36  ? 183 VAL B O   1 
ATOM   3610  C  CB  . VAL B 1 183 ? 25.184  -31.699 21.113  1.00 23.52  ? 183 VAL B CB  1 
ATOM   3611  C  CG1 . VAL B 1 183 ? 24.799  -30.599 20.152  1.00 24.84  ? 183 VAL B CG1 1 
ATOM   3612  C  CG2 . VAL B 1 183 ? 24.336  -32.926 20.859  1.00 25.34  ? 183 VAL B CG2 1 
ATOM   3613  N  N   . GLN B 1 184 ? 27.512  -32.441 23.255  1.00 23.09  ? 184 GLN B N   1 
ATOM   3614  C  CA  . GLN B 1 184 ? 27.653  -33.176 24.487  1.00 24.13  ? 184 GLN B CA  1 
ATOM   3615  C  C   . GLN B 1 184 ? 27.171  -32.296 25.660  1.00 27.02  ? 184 GLN B C   1 
ATOM   3616  O  O   . GLN B 1 184 ? 27.677  -31.200 25.869  1.00 22.04  ? 184 GLN B O   1 
ATOM   3617  C  CB  . GLN B 1 184 ? 29.116  -33.513 24.739  1.00 21.97  ? 184 GLN B CB  1 
ATOM   3618  C  CG  . GLN B 1 184 ? 29.686  -34.518 23.778  1.00 23.60  ? 184 GLN B CG  1 
ATOM   3619  C  CD  . GLN B 1 184 ? 31.147  -34.695 24.081  1.00 29.11  ? 184 GLN B CD  1 
ATOM   3620  O  OE1 . GLN B 1 184 ? 31.937  -33.747 24.062  1.00 30.20  ? 184 GLN B OE1 1 
ATOM   3621  N  NE2 . GLN B 1 184 ? 31.471  -35.898 24.526  1.00 30.22  ? 184 GLN B NE2 1 
ATOM   3622  N  N   . LYS B 1 185 ? 26.310  -32.854 26.521  1.00 27.76  ? 185 LYS B N   1 
ATOM   3623  C  CA  . LYS B 1 185 ? 26.038  -32.224 27.788  1.00 27.81  ? 185 LYS B CA  1 
ATOM   3624  C  C   . LYS B 1 185 ? 27.059  -32.668 28.822  1.00 27.26  ? 185 LYS B C   1 
ATOM   3625  O  O   . LYS B 1 185 ? 27.203  -33.853 29.062  1.00 28.63  ? 185 LYS B O   1 
ATOM   3626  C  CB  . LYS B 1 185 ? 24.633  -32.662 28.185  1.00 26.25  ? 185 LYS B CB  1 
ATOM   3627  C  CG  . LYS B 1 185 ? 24.212  -31.986 29.461  1.00 27.16  ? 185 LYS B CG  1 
ATOM   3628  C  CD  . LYS B 1 185 ? 22.717  -31.756 29.688  1.00 25.94  ? 185 LYS B CD  1 
ATOM   3629  C  CE  . LYS B 1 185 ? 22.135  -33.076 29.844  1.00 30.55  ? 185 LYS B CE  1 
ATOM   3630  N  NZ  . LYS B 1 185 ? 20.709  -33.019 30.038  1.00 35.59  ? 185 LYS B NZ  1 
ATOM   3631  N  N   . TYR B 1 186 ? 27.741  -31.719 29.461  1.00 26.35  ? 186 TYR B N   1 
ATOM   3632  C  CA  . TYR B 1 186 ? 28.721  -32.019 30.500  1.00 27.05  ? 186 TYR B CA  1 
ATOM   3633  C  C   . TYR B 1 186 ? 28.169  -31.553 31.833  1.00 26.75  ? 186 TYR B C   1 
ATOM   3634  O  O   . TYR B 1 186 ? 27.655  -30.451 31.917  1.00 27.51  ? 186 TYR B O   1 
ATOM   3635  C  CB  . TYR B 1 186 ? 30.070  -31.327 30.298  1.00 24.37  ? 186 TYR B CB  1 
ATOM   3636  C  CG  . TYR B 1 186 ? 30.927  -31.973 29.233  1.00 25.03  ? 186 TYR B CG  1 
ATOM   3637  C  CD1 . TYR B 1 186 ? 31.797  -32.989 29.565  1.00 28.36  ? 186 TYR B CD1 1 
ATOM   3638  C  CD2 . TYR B 1 186 ? 30.881  -31.567 27.911  1.00 24.37  ? 186 TYR B CD2 1 
ATOM   3639  C  CE1 . TYR B 1 186 ? 32.555  -33.616 28.597  1.00 27.00  ? 186 TYR B CE1 1 
ATOM   3640  C  CE2 . TYR B 1 186 ? 31.664  -32.157 26.933  1.00 25.45  ? 186 TYR B CE2 1 
ATOM   3641  C  CZ  . TYR B 1 186 ? 32.489  -33.199 27.285  1.00 28.32  ? 186 TYR B CZ  1 
ATOM   3642  O  OH  . TYR B 1 186 ? 33.261  -33.806 26.355  1.00 28.38  ? 186 TYR B OH  1 
ATOM   3643  N  N   . LEU B 1 187 ? 28.359  -32.365 32.863  1.00 28.19  ? 187 LEU B N   1 
ATOM   3644  C  CA  . LEU B 1 187 ? 28.172  -31.894 34.231  1.00 26.60  ? 187 LEU B CA  1 
ATOM   3645  C  C   . LEU B 1 187 ? 29.523  -31.769 34.936  1.00 25.43  ? 187 LEU B C   1 
ATOM   3646  O  O   . LEU B 1 187 ? 30.390  -32.621 34.800  1.00 25.27  ? 187 LEU B O   1 
ATOM   3647  C  CB  . LEU B 1 187 ? 27.247  -32.890 34.933  1.00 26.71  ? 187 LEU B CB  1 
ATOM   3648  C  CG  . LEU B 1 187 ? 25.791  -32.921 34.467  1.00 29.94  ? 187 LEU B CG  1 
ATOM   3649  C  CD1 . LEU B 1 187 ? 25.056  -34.048 35.160  1.00 27.23  ? 187 LEU B CD1 1 
ATOM   3650  C  CD2 . LEU B 1 187 ? 25.137  -31.566 34.837  1.00 36.46  ? 187 LEU B CD2 1 
ATOM   3651  N  N   . HIS B 1 188 ? 29.671  -30.739 35.769  1.00 25.24  ? 188 HIS B N   1 
ATOM   3652  C  CA  . HIS B 1 188 ? 30.928  -30.462 36.408  1.00 23.47  ? 188 HIS B CA  1 
ATOM   3653  C  C   . HIS B 1 188 ? 30.863  -30.801 37.896  1.00 23.95  ? 188 HIS B C   1 
ATOM   3654  O  O   . HIS B 1 188 ? 29.844  -30.691 38.500  1.00 22.55  ? 188 HIS B O   1 
ATOM   3655  C  CB  . HIS B 1 188 ? 31.259  -28.971 36.295  1.00 24.39  ? 188 HIS B CB  1 
ATOM   3656  C  CG  . HIS B 1 188 ? 31.529  -28.546 34.923  1.00 24.43  ? 188 HIS B CG  1 
ATOM   3657  N  ND1 . HIS B 1 188 ? 32.620  -28.995 34.214  1.00 25.48  ? 188 HIS B ND1 1 
ATOM   3658  C  CD2 . HIS B 1 188 ? 30.816  -27.768 34.113  1.00 25.45  ? 188 HIS B CD2 1 
ATOM   3659  C  CE1 . HIS B 1 188 ? 32.558  -28.490 32.991  1.00 27.66  ? 188 HIS B CE1 1 
ATOM   3660  N  NE2 . HIS B 1 188 ? 31.460  -27.737 32.909  1.00 25.76  ? 188 HIS B NE2 1 
ATOM   3661  N  N   . ASP B 1 189 ? 31.981  -31.211 38.454  1.00 27.08  ? 189 ASP B N   1 
ATOM   3662  C  CA  . ASP B 1 189 ? 32.209  -31.278 39.884  1.00 28.19  ? 189 ASP B CA  1 
ATOM   3663  C  C   . ASP B 1 189 ? 32.811  -29.950 40.354  1.00 26.53  ? 189 ASP B C   1 
ATOM   3664  O  O   . ASP B 1 189 ? 34.030  -29.781 40.426  1.00 23.52  ? 189 ASP B O   1 
ATOM   3665  C  CB  . ASP B 1 189 ? 33.123  -32.449 40.170  1.00 27.41  ? 189 ASP B CB  1 
ATOM   3666  C  CG  . ASP B 1 189 ? 33.338  -32.689 41.641  1.00 30.06  ? 189 ASP B CG  1 
ATOM   3667  O  OD1 . ASP B 1 189 ? 32.951  -31.830 42.462  1.00 28.39  ? 189 ASP B OD1 1 
ATOM   3668  O  OD2 . ASP B 1 189 ? 33.890  -33.751 41.922  1.00 36.92  ? 189 ASP B OD2 1 
ATOM   3669  N  N   . ILE B 1 190 ? 31.916  -29.023 40.692  1.00 26.69  ? 190 ILE B N   1 
ATOM   3670  C  CA  . ILE B 1 190 ? 32.307  -27.687 41.067  1.00 27.65  ? 190 ILE B CA  1 
ATOM   3671  C  C   . ILE B 1 190 ? 33.115  -27.668 42.355  1.00 27.51  ? 190 ILE B C   1 
ATOM   3672  O  O   . ILE B 1 190 ? 34.027  -26.855 42.475  1.00 26.47  ? 190 ILE B O   1 
ATOM   3673  C  CB  . ILE B 1 190 ? 31.055  -26.798 41.113  1.00 28.70  ? 190 ILE B CB  1 
ATOM   3674  C  CG1 . ILE B 1 190 ? 30.671  -26.483 39.665  1.00 31.85  ? 190 ILE B CG1 1 
ATOM   3675  C  CG2 . ILE B 1 190 ? 31.294  -25.493 41.855  1.00 28.36  ? 190 ILE B CG2 1 
ATOM   3676  C  CD1 . ILE B 1 190 ? 31.697  -25.705 38.790  1.00 24.58  ? 190 ILE B CD1 1 
ATOM   3677  N  N   . ASP B 1 191 ? 32.800  -28.523 43.321  1.00 27.14  ? 191 ASP B N   1 
ATOM   3678  C  CA  . ASP B 1 191 ? 33.520  -28.442 44.588  1.00 29.33  ? 191 ASP B CA  1 
ATOM   3679  C  C   . ASP B 1 191 ? 34.958  -28.865 44.360  1.00 25.66  ? 191 ASP B C   1 
ATOM   3680  O  O   . ASP B 1 191 ? 35.847  -28.268 44.888  1.00 23.41  ? 191 ASP B O   1 
ATOM   3681  C  CB  . ASP B 1 191 ? 33.051  -29.462 45.608  1.00 41.18  ? 191 ASP B CB  1 
ATOM   3682  C  CG  . ASP B 1 191 ? 31.749  -29.178 46.318  1.00 45.46  ? 191 ASP B CG  1 
ATOM   3683  O  OD1 . ASP B 1 191 ? 31.111  -28.154 45.994  1.00 38.31  ? 191 ASP B OD1 1 
ATOM   3684  O  OD2 . ASP B 1 191 ? 31.482  -29.975 47.244  1.00 65.52  ? 191 ASP B OD2 1 
ATOM   3685  N  N   . ALA B 1 192 ? 35.185  -29.932 43.589  1.00 24.14  ? 192 ALA B N   1 
ATOM   3686  C  CA  . ALA B 1 192 ? 36.545  -30.301 43.272  1.00 24.86  ? 192 ALA B CA  1 
ATOM   3687  C  C   . ALA B 1 192 ? 37.261  -29.149 42.557  1.00 31.68  ? 192 ALA B C   1 
ATOM   3688  O  O   . ALA B 1 192 ? 38.385  -28.842 42.899  1.00 32.03  ? 192 ALA B O   1 
ATOM   3689  C  CB  . ALA B 1 192 ? 36.557  -31.539 42.450  1.00 22.72  ? 192 ALA B CB  1 
ATOM   3690  N  N   . TRP B 1 193 ? 36.621  -28.544 41.523  1.00 32.29  ? 193 TRP B N   1 
ATOM   3691  C  CA  . TRP B 1 193 ? 37.207  -27.477 40.730  1.00 26.64  ? 193 TRP B CA  1 
ATOM   3692  C  C   . TRP B 1 193 ? 37.613  -26.290 41.598  1.00 25.32  ? 193 TRP B C   1 
ATOM   3693  O  O   . TRP B 1 193 ? 38.711  -25.777 41.440  1.00 26.60  ? 193 TRP B O   1 
ATOM   3694  C  CB  . TRP B 1 193 ? 36.197  -27.043 39.660  1.00 30.67  ? 193 TRP B CB  1 
ATOM   3695  C  CG  . TRP B 1 193 ? 36.691  -25.938 38.749  1.00 24.86  ? 193 TRP B CG  1 
ATOM   3696  C  CD1 . TRP B 1 193 ? 36.209  -24.677 38.646  1.00 23.20  ? 193 TRP B CD1 1 
ATOM   3697  C  CD2 . TRP B 1 193 ? 37.739  -26.051 37.769  1.00 25.00  ? 193 TRP B CD2 1 
ATOM   3698  N  NE1 . TRP B 1 193 ? 36.870  -24.005 37.665  1.00 23.43  ? 193 TRP B NE1 1 
ATOM   3699  C  CE2 . TRP B 1 193 ? 37.832  -24.806 37.133  1.00 24.49  ? 193 TRP B CE2 1 
ATOM   3700  C  CE3 . TRP B 1 193 ? 38.622  -27.077 37.410  1.00 23.95  ? 193 TRP B CE3 1 
ATOM   3701  C  CZ2 . TRP B 1 193 ? 38.772  -24.558 36.151  1.00 26.27  ? 193 TRP B CZ2 1 
ATOM   3702  C  CZ3 . TRP B 1 193 ? 39.579  -26.814 36.461  1.00 29.70  ? 193 TRP B CZ3 1 
ATOM   3703  C  CH2 . TRP B 1 193 ? 39.653  -25.564 35.842  1.00 27.87  ? 193 TRP B CH2 1 
ATOM   3704  N  N   . GLU B 1 194 ? 36.744  -25.910 42.531  1.00 25.35  ? 194 GLU B N   1 
ATOM   3705  C  CA  . GLU B 1 194 ? 36.959  -24.749 43.367  1.00 27.87  ? 194 GLU B CA  1 
ATOM   3706  C  C   . GLU B 1 194 ? 37.997  -25.041 44.423  1.00 30.21  ? 194 GLU B C   1 
ATOM   3707  O  O   . GLU B 1 194 ? 38.512  -24.131 45.018  1.00 29.90  ? 194 GLU B O   1 
ATOM   3708  C  CB  . GLU B 1 194 ? 35.652  -24.175 43.890  1.00 31.02  ? 194 GLU B CB  1 
ATOM   3709  C  CG  . GLU B 1 194 ? 35.195  -23.087 42.897  1.00 44.76  ? 194 GLU B CG  1 
ATOM   3710  C  CD  . GLU B 1 194 ? 33.740  -22.679 42.963  1.00 60.13  ? 194 GLU B CD  1 
ATOM   3711  O  OE1 . GLU B 1 194 ? 33.087  -22.765 44.037  1.00 67.63  ? 194 GLU B OE1 1 
ATOM   3712  O  OE2 . GLU B 1 194 ? 33.248  -22.282 41.898  1.00 65.46  ? 194 GLU B OE2 1 
ATOM   3713  N  N   . GLY B 1 195 ? 38.409  -26.296 44.572  1.00 28.90  ? 195 GLY B N   1 
ATOM   3714  C  CA  . GLY B 1 195 ? 39.503  -26.530 45.485  1.00 29.07  ? 195 GLY B CA  1 
ATOM   3715  C  C   . GLY B 1 195 ? 40.880  -26.316 44.870  1.00 33.16  ? 195 GLY B C   1 
ATOM   3716  O  O   . GLY B 1 195 ? 41.830  -26.200 45.647  1.00 34.48  ? 195 GLY B O   1 
ATOM   3717  N  N   . LEU B 1 196 ? 40.981  -26.205 43.533  1.00 27.62  ? 196 LEU B N   1 
ATOM   3718  C  CA  . LEU B 1 196 ? 42.233  -25.852 42.868  1.00 25.83  ? 196 LEU B CA  1 
ATOM   3719  C  C   . LEU B 1 196 ? 42.540  -24.377 43.071  1.00 27.37  ? 196 LEU B C   1 
ATOM   3720  O  O   . LEU B 1 196 ? 41.624  -23.579 43.134  1.00 28.42  ? 196 LEU B O   1 
ATOM   3721  C  CB  . LEU B 1 196 ? 42.074  -26.143 41.388  1.00 28.33  ? 196 LEU B CB  1 
ATOM   3722  C  CG  . LEU B 1 196 ? 42.483  -27.518 40.875  1.00 31.03  ? 196 LEU B CG  1 
ATOM   3723  C  CD1 . LEU B 1 196 ? 41.688  -28.603 41.514  1.00 38.10  ? 196 LEU B CD1 1 
ATOM   3724  C  CD2 . LEU B 1 196 ? 42.270  -27.532 39.428  1.00 35.39  ? 196 LEU B CD2 1 
ATOM   3725  N  N   . SER B 1 197 ? 43.812  -24.017 43.197  1.00 27.56  ? 197 SER B N   1 
ATOM   3726  C  CA  . SER B 1 197 ? 44.218  -22.628 43.126  1.00 27.20  ? 197 SER B CA  1 
ATOM   3727  C  C   . SER B 1 197 ? 43.986  -22.139 41.690  1.00 30.46  ? 197 SER B C   1 
ATOM   3728  O  O   . SER B 1 197 ? 43.885  -22.920 40.746  1.00 23.37  ? 197 SER B O   1 
ATOM   3729  C  CB  . SER B 1 197 ? 45.683  -22.469 43.441  1.00 28.94  ? 197 SER B CB  1 
ATOM   3730  O  OG  . SER B 1 197 ? 46.442  -23.174 42.453  1.00 25.32  ? 197 SER B OG  1 
ATOM   3731  N  N   . VAL B 1 198 ? 43.960  -20.822 41.499  1.00 27.32  ? 198 VAL B N   1 
ATOM   3732  C  CA  . VAL B 1 198 ? 43.823  -20.281 40.155  1.00 27.26  ? 198 VAL B CA  1 
ATOM   3733  C  C   . VAL B 1 198 ? 44.960  -20.803 39.273  1.00 25.57  ? 198 VAL B C   1 
ATOM   3734  O  O   . VAL B 1 198 ? 44.706  -21.129 38.119  1.00 26.45  ? 198 VAL B O   1 
ATOM   3735  C  CB  . VAL B 1 198 ? 43.763  -18.732 40.220  1.00 23.60  ? 198 VAL B CB  1 
ATOM   3736  C  CG1 . VAL B 1 198 ? 44.011  -18.056 38.870  1.00 24.83  ? 198 VAL B CG1 1 
ATOM   3737  C  CG2 . VAL B 1 198 ? 42.449  -18.253 40.849  1.00 24.85  ? 198 VAL B CG2 1 
ATOM   3738  N  N   . GLU B 1 199 ? 46.185  -20.890 39.802  1.00 25.25  ? 199 GLU B N   1 
ATOM   3739  C  CA  . GLU B 1 199 ? 47.338  -21.298 38.997  1.00 28.83  ? 199 GLU B CA  1 
ATOM   3740  C  C   . GLU B 1 199 ? 47.151  -22.729 38.502  1.00 27.11  ? 199 GLU B C   1 
ATOM   3741  O  O   . GLU B 1 199 ? 47.491  -22.992 37.353  1.00 28.02  ? 199 GLU B O   1 
ATOM   3742  C  CB  . GLU B 1 199 ? 48.738  -21.093 39.622  1.00 35.75  ? 199 GLU B CB  1 
ATOM   3743  C  CG  . GLU B 1 199 ? 48.954  -19.626 40.084  1.00 43.60  ? 199 GLU B CG  1 
ATOM   3744  C  CD  . GLU B 1 199 ? 48.101  -18.929 41.217  1.00 38.61  ? 199 GLU B CD  1 
ATOM   3745  O  OE1 . GLU B 1 199 ? 47.431  -19.554 42.094  1.00 30.94  ? 199 GLU B OE1 1 
ATOM   3746  O  OE2 . GLU B 1 199 ? 48.154  -17.640 41.237  1.00 35.17  ? 199 GLU B OE2 1 
ATOM   3747  N  N   . ALA B 1 200 ? 46.577  -23.595 39.355  1.00 23.76  ? 200 ALA B N   1 
ATOM   3748  C  CA  . ALA B 1 200 ? 46.265  -24.978 38.996  1.00 25.37  ? 200 ALA B CA  1 
ATOM   3749  C  C   . ALA B 1 200 ? 45.143  -25.078 37.943  1.00 23.97  ? 200 ALA B C   1 
ATOM   3750  O  O   . ALA B 1 200 ? 45.167  -25.941 37.053  1.00 24.31  ? 200 ALA B O   1 
ATOM   3751  C  CB  . ALA B 1 200 ? 45.898  -25.751 40.257  1.00 24.97  ? 200 ALA B CB  1 
ATOM   3752  N  N   . GLN B 1 201 ? 44.157  -24.169 38.041  1.00 24.79  ? 201 GLN B N   1 
ATOM   3753  C  CA  . GLN B 1 201 ? 43.095  -24.140 37.062  1.00 22.70  ? 201 GLN B CA  1 
ATOM   3754  C  C   . GLN B 1 201 ? 43.639  -23.730 35.699  1.00 21.72  ? 201 GLN B C   1 
ATOM   3755  O  O   . GLN B 1 201 ? 43.254  -24.303 34.668  1.00 22.78  ? 201 GLN B O   1 
ATOM   3756  C  CB  . GLN B 1 201 ? 42.009  -23.201 37.531  1.00 22.66  ? 201 GLN B CB  1 
ATOM   3757  C  CG  . GLN B 1 201 ? 41.262  -23.650 38.763  1.00 25.24  ? 201 GLN B CG  1 
ATOM   3758  C  CD  . GLN B 1 201 ? 40.106  -22.744 39.096  1.00 26.40  ? 201 GLN B CD  1 
ATOM   3759  O  OE1 . GLN B 1 201 ? 39.993  -21.636 38.598  1.00 24.71  ? 201 GLN B OE1 1 
ATOM   3760  N  NE2 . GLN B 1 201 ? 39.213  -23.202 39.946  1.00 24.52  ? 201 GLN B NE2 1 
ATOM   3761  N  N   . GLU B 1 202 ? 44.537  -22.752 35.707  1.00 20.82  ? 202 GLU B N   1 
ATOM   3762  C  CA  . GLU B 1 202 ? 45.119  -22.277 34.467  1.00 22.84  ? 202 GLU B CA  1 
ATOM   3763  C  C   . GLU B 1 202 ? 45.926  -23.381 33.791  1.00 27.58  ? 202 GLU B C   1 
ATOM   3764  O  O   . GLU B 1 202 ? 46.039  -23.417 32.572  1.00 29.48  ? 202 GLU B O   1 
ATOM   3765  C  CB  . GLU B 1 202 ? 46.022  -21.083 34.730  1.00 25.41  ? 202 GLU B CB  1 
ATOM   3766  C  CG  . GLU B 1 202 ? 45.236  -19.826 35.085  1.00 25.51  ? 202 GLU B CG  1 
ATOM   3767  C  CD  . GLU B 1 202 ? 46.058  -18.704 35.660  1.00 26.15  ? 202 GLU B CD  1 
ATOM   3768  O  OE1 . GLU B 1 202 ? 47.164  -18.916 36.095  1.00 27.03  ? 202 GLU B OE1 1 
ATOM   3769  O  OE2 . GLU B 1 202 ? 45.561  -17.582 35.659  1.00 27.40  ? 202 GLU B OE2 1 
ATOM   3770  N  N   . ARG B 1 203 ? 46.471  -24.305 34.599  1.00 30.51  ? 203 ARG B N   1 
ATOM   3771  C  CA  . ARG B 1 203 ? 47.241  -25.439 34.094  1.00 31.27  ? 203 ARG B CA  1 
ATOM   3772  C  C   . ARG B 1 203 ? 46.319  -26.484 33.488  1.00 29.82  ? 203 ARG B C   1 
ATOM   3773  O  O   . ARG B 1 203 ? 46.711  -27.209 32.589  1.00 28.18  ? 203 ARG B O   1 
ATOM   3774  C  CB  . ARG B 1 203 ? 48.206  -25.961 35.172  1.00 38.04  ? 203 ARG B CB  1 
ATOM   3775  C  CG  . ARG B 1 203 ? 49.549  -25.220 35.116  1.00 48.89  ? 203 ARG B CG  1 
ATOM   3776  C  CD  . ARG B 1 203 ? 50.824  -25.911 35.647  1.00 58.99  ? 203 ARG B CD  1 
ATOM   3777  N  NE  . ARG B 1 203 ? 50.528  -26.157 37.061  1.00 58.66  ? 203 ARG B NE  1 
ATOM   3778  C  CZ  . ARG B 1 203 ? 50.486  -25.187 37.994  1.00 71.12  ? 203 ARG B CZ  1 
ATOM   3779  N  NH1 . ARG B 1 203 ? 50.860  -23.933 37.716  1.00 90.28  ? 203 ARG B NH1 1 
ATOM   3780  N  NH2 . ARG B 1 203 ? 50.066  -25.468 39.218  1.00 51.85  ? 203 ARG B NH2 1 
ATOM   3781  N  N   . VAL B 1 204 ? 45.080  -26.535 33.953  1.00 28.88  ? 204 VAL B N   1 
ATOM   3782  C  CA  . VAL B 1 204 ? 44.118  -27.436 33.344  1.00 29.24  ? 204 VAL B CA  1 
ATOM   3783  C  C   . VAL B 1 204 ? 43.648  -26.906 31.973  1.00 28.81  ? 204 VAL B C   1 
ATOM   3784  O  O   . VAL B 1 204 ? 43.501  -27.664 31.002  1.00 26.30  ? 204 VAL B O   1 
ATOM   3785  C  CB  . VAL B 1 204 ? 42.957  -27.647 34.311  1.00 28.35  ? 204 VAL B CB  1 
ATOM   3786  C  CG1 . VAL B 1 204 ? 41.828  -28.432 33.630  1.00 27.45  ? 204 VAL B CG1 1 
ATOM   3787  C  CG2 . VAL B 1 204 ? 43.449  -28.357 35.538  1.00 27.15  ? 204 VAL B CG2 1 
ATOM   3788  N  N   . ILE B 1 205 ? 43.400  -25.605 31.891  1.00 25.84  ? 205 ILE B N   1 
ATOM   3789  C  CA  . ILE B 1 205 ? 42.777  -25.051 30.700  1.00 25.33  ? 205 ILE B CA  1 
ATOM   3790  C  C   . ILE B 1 205 ? 43.865  -24.744 29.671  1.00 23.40  ? 205 ILE B C   1 
ATOM   3791  O  O   . ILE B 1 205 ? 43.722  -25.068 28.507  1.00 24.92  ? 205 ILE B O   1 
ATOM   3792  C  CB  . ILE B 1 205 ? 41.976  -23.796 31.098  1.00 24.70  ? 205 ILE B CB  1 
ATOM   3793  C  CG1 . ILE B 1 205 ? 40.900  -24.080 32.089  1.00 24.09  ? 205 ILE B CG1 1 
ATOM   3794  C  CG2 . ILE B 1 205 ? 41.431  -23.089 29.874  1.00 27.56  ? 205 ILE B CG2 1 
ATOM   3795  C  CD1 . ILE B 1 205 ? 39.789  -24.923 31.572  1.00 26.46  ? 205 ILE B CD1 1 
ATOM   3796  N  N   . GLY B 1 206 ? 44.919  -24.062 30.086  1.00 21.75  ? 206 GLY B N   1 
ATOM   3797  C  CA  . GLY B 1 206 ? 45.945  -23.637 29.157  1.00 24.06  ? 206 GLY B CA  1 
ATOM   3798  C  C   . GLY B 1 206 ? 45.993  -22.139 28.957  1.00 23.18  ? 206 GLY B C   1 
ATOM   3799  O  O   . GLY B 1 206 ? 46.792  -21.689 28.174  1.00 27.65  ? 206 GLY B O   1 
ATOM   3800  N  N   . ARG B 1 207 ? 45.179  -21.371 29.673  1.00 22.12  ? 207 ARG B N   1 
ATOM   3801  C  CA  . ARG B 1 207 ? 45.179  -19.921 29.536  1.00 22.54  ? 207 ARG B CA  1 
ATOM   3802  C  C   . ARG B 1 207 ? 45.034  -19.309 30.907  1.00 23.12  ? 207 ARG B C   1 
ATOM   3803  O  O   . ARG B 1 207 ? 44.591  -20.000 31.842  1.00 24.25  ? 207 ARG B O   1 
ATOM   3804  C  CB  . ARG B 1 207 ? 43.958  -19.481 28.727  1.00 22.72  ? 207 ARG B CB  1 
ATOM   3805  C  CG  . ARG B 1 207 ? 43.683  -20.340 27.500  1.00 23.40  ? 207 ARG B CG  1 
ATOM   3806  C  CD  . ARG B 1 207 ? 42.534  -19.790 26.700  1.00 28.11  ? 207 ARG B CD  1 
ATOM   3807  N  NE  . ARG B 1 207 ? 42.679  -18.410 26.158  1.00 31.18  ? 207 ARG B NE  1 
ATOM   3808  C  CZ  . ARG B 1 207 ? 43.228  -17.995 24.998  1.00 33.32  ? 207 ARG B CZ  1 
ATOM   3809  N  NH1 . ARG B 1 207 ? 43.675  -16.752 24.966  1.00 27.43  ? 207 ARG B NH1 1 
ATOM   3810  N  NH2 . ARG B 1 207 ? 43.445  -18.814 23.954  1.00 31.67  ? 207 ARG B NH2 1 
ATOM   3811  N  N   . ARG B 1 208 ? 45.368  -18.027 31.022  1.00 22.38  ? 208 ARG B N   1 
ATOM   3812  C  CA  . ARG B 1 208 ? 45.267  -17.319 32.302  1.00 24.63  ? 208 ARG B CA  1 
ATOM   3813  C  C   . ARG B 1 208 ? 43.809  -16.992 32.602  1.00 25.28  ? 208 ARG B C   1 
ATOM   3814  O  O   . ARG B 1 208 ? 43.045  -16.687 31.708  1.00 28.30  ? 208 ARG B O   1 
ATOM   3815  C  CB  . ARG B 1 208 ? 45.925  -15.945 32.258  1.00 30.80  ? 208 ARG B CB  1 
ATOM   3816  C  CG  . ARG B 1 208 ? 47.417  -15.988 31.951  1.00 36.78  ? 208 ARG B CG  1 
ATOM   3817  C  CD  . ARG B 1 208 ? 48.250  -16.763 32.961  1.00 38.15  ? 208 ARG B CD  1 
ATOM   3818  N  NE  . ARG B 1 208 ? 48.150  -16.242 34.330  1.00 49.09  ? 208 ARG B NE  1 
ATOM   3819  C  CZ  . ARG B 1 208 ? 48.630  -15.075 34.762  1.00 52.52  ? 208 ARG B CZ  1 
ATOM   3820  N  NH1 . ARG B 1 208 ? 49.357  -14.326 33.964  1.00 82.88  ? 208 ARG B NH1 1 
ATOM   3821  N  NH2 . ARG B 1 208 ? 48.438  -14.663 36.000  1.00 46.13  ? 208 ARG B NH2 1 
ATOM   3822  N  N   . LYS B 1 209 ? 43.394  -17.075 33.849  1.00 27.86  ? 209 LYS B N   1 
ATOM   3823  C  CA  . LYS B 1 209 ? 41.962  -17.009 34.169  1.00 25.19  ? 209 LYS B CA  1 
ATOM   3824  C  C   . LYS B 1 209 ? 41.442  -15.577 34.071  1.00 24.40  ? 209 LYS B C   1 
ATOM   3825  O  O   . LYS B 1 209 ? 40.478  -15.313 33.339  1.00 26.50  ? 209 LYS B O   1 
ATOM   3826  C  CB  . LYS B 1 209 ? 41.693  -17.605 35.550  1.00 25.52  ? 209 LYS B CB  1 
ATOM   3827  C  CG  . LYS B 1 209 ? 40.268  -17.736 35.878  1.00 24.47  ? 209 LYS B CG  1 
ATOM   3828  C  CD  . LYS B 1 209 ? 40.005  -18.416 37.201  1.00 25.03  ? 209 LYS B CD  1 
ATOM   3829  C  CE  . LYS B 1 209 ? 38.583  -18.881 37.181  1.00 28.94  ? 209 LYS B CE  1 
ATOM   3830  N  NZ  . LYS B 1 209 ? 38.212  -19.468 38.448  1.00 31.60  ? 209 LYS B NZ  1 
ATOM   3831  N  N   . MET B 1 210 ? 42.068  -14.648 34.778  1.00 24.31  ? 210 MET B N   1 
ATOM   3832  C  CA  . MET B 1 210 ? 41.572  -13.291 34.701  1.00 32.39  ? 210 MET B CA  1 
ATOM   3833  C  C   . MET B 1 210 ? 41.766  -12.636 33.324  1.00 32.77  ? 210 MET B C   1 
ATOM   3834  O  O   . MET B 1 210 ? 40.783  -12.119 32.858  1.00 32.36  ? 210 MET B O   1 
ATOM   3835  C  CB  . MET B 1 210 ? 42.085  -12.351 35.769  1.00 38.91  ? 210 MET B CB  1 
ATOM   3836  C  CG  . MET B 1 210 ? 41.166  -11.154 35.618  1.00 59.61  ? 210 MET B CG  1 
ATOM   3837  S  SD  . MET B 1 210 ? 41.530  -9.890  36.822  1.00 93.33  ? 210 MET B SD  1 
ATOM   3838  C  CE  . MET B 1 210 ? 43.270  -9.462  36.486  1.00 77.61  ? 210 MET B CE  1 
ATOM   3839  N  N   . THR B 1 211 ? 42.929  -12.729 32.647  1.00 29.14  ? 211 THR B N   1 
ATOM   3840  C  CA  . THR B 1 211 ? 43.227  -11.940 31.455  1.00 25.02  ? 211 THR B CA  1 
ATOM   3841  C  C   . THR B 1 211 ? 43.024  -12.755 30.180  1.00 23.92  ? 211 THR B C   1 
ATOM   3842  O  O   . THR B 1 211 ? 43.089  -12.222 29.087  1.00 23.69  ? 211 THR B O   1 
ATOM   3843  C  CB  . THR B 1 211 ? 44.662  -11.414 31.475  1.00 25.06  ? 211 THR B CB  1 
ATOM   3844  O  OG1 . THR B 1 211 ? 45.532  -12.540 31.557  1.00 27.56  ? 211 THR B OG1 1 
ATOM   3845  C  CG2 . THR B 1 211 ? 44.861  -10.434 32.603  1.00 23.98  ? 211 THR B CG2 1 
ATOM   3846  N  N   . ASP B 1 212 ? 42.794  -14.061 30.276  1.00 21.28  ? 212 ASP B N   1 
ATOM   3847  C  CA  . ASP B 1 212 ? 42.547  -14.890 29.108  1.00 23.07  ? 212 ASP B CA  1 
ATOM   3848  C  C   . ASP B 1 212 ? 43.734  -14.863 28.141  1.00 23.75  ? 212 ASP B C   1 
ATOM   3849  O  O   . ASP B 1 212 ? 43.581  -15.181 26.989  1.00 22.54  ? 212 ASP B O   1 
ATOM   3850  C  CB  . ASP B 1 212 ? 41.270  -14.504 28.371  1.00 23.69  ? 212 ASP B CB  1 
ATOM   3851  C  CG  . ASP B 1 212 ? 40.661  -15.552 27.444  1.00 25.52  ? 212 ASP B CG  1 
ATOM   3852  O  OD1 . ASP B 1 212 ? 40.900  -16.776 27.631  1.00 24.91  ? 212 ASP B OD1 1 
ATOM   3853  O  OD2 . ASP B 1 212 ? 39.917  -15.150 26.532  1.00 26.94  ? 212 ASP B OD2 1 
ATOM   3854  N  N   . VAL B 1 213 ? 44.944  -14.619 28.615  1.00 27.17  ? 213 VAL B N   1 
ATOM   3855  C  CA  . VAL B 1 213 ? 46.121  -14.757 27.754  1.00 31.12  ? 213 VAL B CA  1 
ATOM   3856  C  C   . VAL B 1 213 ? 46.589  -16.214 27.748  1.00 29.63  ? 213 VAL B C   1 
ATOM   3857  O  O   . VAL B 1 213 ? 46.720  -16.831 28.815  1.00 31.72  ? 213 VAL B O   1 
ATOM   3858  C  CB  . VAL B 1 213 ? 47.264  -13.837 28.265  1.00 30.00  ? 213 VAL B CB  1 
ATOM   3859  C  CG1 . VAL B 1 213 ? 48.598  -14.076 27.543  1.00 29.49  ? 213 VAL B CG1 1 
ATOM   3860  C  CG2 . VAL B 1 213 ? 46.869  -12.370 28.197  1.00 29.90  ? 213 VAL B CG2 1 
ATOM   3861  N  N   . GLU B 1 214 ? 46.869  -16.758 26.567  1.00 30.42  ? 214 GLU B N   1 
ATOM   3862  C  CA  . GLU B 1 214 ? 47.351  -18.138 26.486  1.00 32.75  ? 214 GLU B CA  1 
ATOM   3863  C  C   . GLU B 1 214 ? 48.693  -18.328 27.231  1.00 31.05  ? 214 GLU B C   1 
ATOM   3864  O  O   . GLU B 1 214 ? 49.512  -17.441 27.286  1.00 30.70  ? 214 GLU B O   1 
ATOM   3865  C  CB  . GLU B 1 214 ? 47.357  -18.456 24.998  1.00 35.51  ? 214 GLU B CB  1 
ATOM   3866  C  CG  . GLU B 1 214 ? 47.922  -19.820 24.653  1.00 40.09  ? 214 GLU B CG  1 
ATOM   3867  C  CD  . GLU B 1 214 ? 47.578  -20.163 23.217  1.00 46.76  ? 214 GLU B CD  1 
ATOM   3868  O  OE1 . GLU B 1 214 ? 46.909  -19.450 22.410  1.00 57.10  ? 214 GLU B OE1 1 
ATOM   3869  O  OE2 . GLU B 1 214 ? 47.922  -21.305 22.970  1.00 47.18  ? 214 GLU B OE2 1 
ATOM   3870  N  N   . LEU B 1 215 ? 48.861  -19.432 27.939  1.00 25.89  ? 215 LEU B N   1 
ATOM   3871  C  CA  . LEU B 1 215 ? 50.123  -19.720 28.590  1.00 30.38  ? 215 LEU B CA  1 
ATOM   3872  C  C   . LEU B 1 215 ? 51.131  -19.970 27.461  1.00 34.45  ? 215 LEU B C   1 
ATOM   3873  O  O   . LEU B 1 215 ? 50.788  -20.593 26.455  1.00 30.81  ? 215 LEU B O   1 
ATOM   3874  C  CB  . LEU B 1 215 ? 50.025  -20.991 29.450  1.00 32.69  ? 215 LEU B CB  1 
ATOM   3875  C  CG  . LEU B 1 215 ? 49.107  -21.034 30.682  1.00 32.43  ? 215 LEU B CG  1 
ATOM   3876  C  CD1 . LEU B 1 215 ? 49.336  -22.343 31.423  1.00 34.61  ? 215 LEU B CD1 1 
ATOM   3877  C  CD2 . LEU B 1 215 ? 49.286  -19.857 31.574  1.00 33.06  ? 215 LEU B CD2 1 
ATOM   3878  N  N   . SER B 1 216 ? 52.401  -19.616 27.666  1.00 47.49  ? 216 SER B N   1 
ATOM   3879  C  CA  . SER B 1 216 ? 53.394  -19.796 26.599  1.00 58.64  ? 216 SER B CA  1 
ATOM   3880  C  C   . SER B 1 216 ? 53.732  -21.269 26.420  1.00 51.10  ? 216 SER B C   1 
ATOM   3881  O  O   . SER B 1 216 ? 53.553  -22.038 27.368  1.00 42.17  ? 216 SER B O   1 
ATOM   3882  C  CB  . SER B 1 216 ? 54.628  -19.011 26.867  1.00 55.15  ? 216 SER B CB  1 
ATOM   3883  O  OG  . SER B 1 216 ? 55.164  -19.446 28.101  1.00 57.13  ? 216 SER B OG  1 
ATOM   3884  N  N   . ASP B 1 217 ? 54.228  -21.610 25.216  1.00 56.26  ? 217 ASP B N   1 
ATOM   3885  C  CA  . ASP B 1 217 ? 54.485  -22.992 24.796  1.00 68.94  ? 217 ASP B CA  1 
ATOM   3886  C  C   . ASP B 1 217 ? 55.375  -23.730 25.796  1.00 52.96  ? 217 ASP B C   1 
ATOM   3887  O  O   . ASP B 1 217 ? 55.220  -24.926 26.016  1.00 45.49  ? 217 ASP B O   1 
ATOM   3888  C  CB  . ASP B 1 217 ? 55.171  -23.088 23.438  1.00 72.81  ? 217 ASP B CB  1 
ATOM   3889  C  CG  . ASP B 1 217 ? 54.396  -22.484 22.289  1.00 76.83  ? 217 ASP B CG  1 
ATOM   3890  O  OD1 . ASP B 1 217 ? 53.219  -22.870 22.124  1.00 73.76  ? 217 ASP B OD1 1 
ATOM   3891  O  OD2 . ASP B 1 217 ? 54.984  -21.643 21.601  1.00 81.85  ? 217 ASP B OD2 1 
ATOM   3892  N  N   . ASP B 1 218 ? 56.288  -22.996 26.416  1.00 51.07  ? 218 ASP B N   1 
ATOM   3893  C  CA  . ASP B 1 218 ? 57.190  -23.615 27.361  1.00 68.53  ? 218 ASP B CA  1 
ATOM   3894  C  C   . ASP B 1 218 ? 56.525  -23.903 28.713  1.00 59.97  ? 218 ASP B C   1 
ATOM   3895  O  O   . ASP B 1 218 ? 57.049  -24.689 29.470  1.00 62.89  ? 218 ASP B O   1 
ATOM   3896  C  CB  . ASP B 1 218 ? 58.518  -22.859 27.399  1.00 83.74  ? 218 ASP B CB  1 
ATOM   3897  C  CG  . ASP B 1 218 ? 58.555  -21.460 28.003  1.00 76.03  ? 218 ASP B CG  1 
ATOM   3898  O  OD1 . ASP B 1 218 ? 57.531  -20.993 28.535  1.00 65.70  ? 218 ASP B OD1 1 
ATOM   3899  O  OD2 . ASP B 1 218 ? 59.608  -20.815 27.883  1.00 84.78  ? 218 ASP B OD2 1 
ATOM   3900  N  N   . VAL B 1 219 ? 55.369  -23.335 29.061  1.00 56.13  ? 219 VAL B N   1 
ATOM   3901  C  CA  . VAL B 1 219 ? 54.811  -23.628 30.388  1.00 49.32  ? 219 VAL B CA  1 
ATOM   3902  C  C   . VAL B 1 219 ? 53.421  -24.277 30.274  1.00 44.06  ? 219 VAL B C   1 
ATOM   3903  O  O   . VAL B 1 219 ? 52.793  -24.679 31.247  1.00 49.86  ? 219 VAL B O   1 
ATOM   3904  C  CB  . VAL B 1 219 ? 54.783  -22.384 31.306  1.00 46.29  ? 219 VAL B CB  1 
ATOM   3905  C  CG1 . VAL B 1 219 ? 54.409  -21.126 30.556  1.00 52.29  ? 219 VAL B CG1 1 
ATOM   3906  C  CG2 . VAL B 1 219 ? 53.816  -22.509 32.476  1.00 43.59  ? 219 VAL B CG2 1 
ATOM   3907  N  N   . LYS B 1 220 ? 52.884  -24.369 29.072  1.00 40.88  ? 220 LYS B N   1 
ATOM   3908  C  CA  . LYS B 1 220 ? 51.572  -24.938 28.954  1.00 43.97  ? 220 LYS B CA  1 
ATOM   3909  C  C   . LYS B 1 220 ? 51.725  -26.435 29.066  1.00 34.39  ? 220 LYS B C   1 
ATOM   3910  O  O   . LYS B 1 220 ? 52.409  -27.037 28.275  1.00 45.23  ? 220 LYS B O   1 
ATOM   3911  C  CB  . LYS B 1 220 ? 51.034  -24.534 27.588  1.00 55.42  ? 220 LYS B CB  1 
ATOM   3912  C  CG  . LYS B 1 220 ? 49.691  -25.148 27.211  1.00 57.78  ? 220 LYS B CG  1 
ATOM   3913  C  CD  . LYS B 1 220 ? 49.383  -24.960 25.730  1.00 54.48  ? 220 LYS B CD  1 
ATOM   3914  C  CE  . LYS B 1 220 ? 49.583  -23.495 25.473  1.00 55.31  ? 220 LYS B CE  1 
ATOM   3915  N  NZ  . LYS B 1 220 ? 49.227  -23.258 24.092  1.00 59.79  ? 220 LYS B NZ  1 
ATOM   3916  N  N   . PRO B 1 221 ? 51.042  -27.111 29.987  1.00 29.90  ? 221 PRO B N   1 
ATOM   3917  C  CA  . PRO B 1 221 ? 51.024  -28.559 30.025  1.00 27.04  ? 221 PRO B CA  1 
ATOM   3918  C  C   . PRO B 1 221 ? 50.479  -29.234 28.777  1.00 29.15  ? 221 PRO B C   1 
ATOM   3919  O  O   . PRO B 1 221 ? 49.563  -28.752 28.095  1.00 29.44  ? 221 PRO B O   1 
ATOM   3920  C  CB  . PRO B 1 221 ? 50.140  -28.893 31.233  1.00 27.01  ? 221 PRO B CB  1 
ATOM   3921  C  CG  . PRO B 1 221 ? 50.254  -27.686 32.073  1.00 27.64  ? 221 PRO B CG  1 
ATOM   3922  C  CD  . PRO B 1 221 ? 50.253  -26.544 31.075  1.00 32.96  ? 221 PRO B CD  1 
ATOM   3923  N  N   . ALA B 1 222 ? 51.021  -30.429 28.570  1.00 28.97  ? 222 ALA B N   1 
ATOM   3924  C  CA  . ALA B 1 222 ? 50.698  -31.251 27.433  1.00 33.16  ? 222 ALA B CA  1 
ATOM   3925  C  C   . ALA B 1 222 ? 49.275  -31.781 27.562  1.00 29.96  ? 222 ALA B C   1 
ATOM   3926  O  O   . ALA B 1 222 ? 48.701  -32.201 26.579  1.00 37.61  ? 222 ALA B O   1 
ATOM   3927  C  CB  . ALA B 1 222 ? 51.719  -32.375 27.400  1.00 33.71  ? 222 ALA B CB  1 
ATOM   3928  N  N   . ASP B 1 223 ? 48.764  -31.897 28.793  1.00 29.20  ? 223 ASP B N   1 
ATOM   3929  C  CA  . ASP B 1 223 ? 47.452  -32.482 29.047  1.00 28.17  ? 223 ASP B CA  1 
ATOM   3930  C  C   . ASP B 1 223 ? 46.442  -31.361 29.383  1.00 31.75  ? 223 ASP B C   1 
ATOM   3931  O  O   . ASP B 1 223 ? 45.343  -31.621 29.889  1.00 27.59  ? 223 ASP B O   1 
ATOM   3932  C  CB  . ASP B 1 223 ? 47.548  -33.568 30.102  1.00 31.64  ? 223 ASP B CB  1 
ATOM   3933  C  CG  . ASP B 1 223 ? 48.008  -33.111 31.492  1.00 34.66  ? 223 ASP B CG  1 
ATOM   3934  O  OD1 . ASP B 1 223 ? 48.550  -31.967 31.603  1.00 31.70  ? 223 ASP B OD1 1 
ATOM   3935  O  OD2 . ASP B 1 223 ? 47.805  -33.886 32.457  1.00 36.60  ? 223 ASP B OD2 1 
ATOM   3936  N  N   . SER B 1 224 ? 46.801  -30.093 29.088  1.00 30.56  ? 224 SER B N   1 
ATOM   3937  C  CA  . SER B 1 224 ? 45.871  -28.979 29.211  1.00 28.70  ? 224 SER B CA  1 
ATOM   3938  C  C   . SER B 1 224 ? 44.919  -29.036 28.028  1.00 26.51  ? 224 SER B C   1 
ATOM   3939  O  O   . SER B 1 224 ? 45.233  -29.584 26.992  1.00 24.31  ? 224 SER B O   1 
ATOM   3940  C  CB  . SER B 1 224 ? 46.556  -27.663 29.289  1.00 27.23  ? 224 SER B CB  1 
ATOM   3941  O  OG  . SER B 1 224 ? 47.145  -27.339 28.041  1.00 28.30  ? 224 SER B OG  1 
ATOM   3942  N  N   . HIS B 1 225 ? 43.732  -28.467 28.230  1.00 29.97  ? 225 HIS B N   1 
ATOM   3943  C  CA  . HIS B 1 225 ? 42.626  -28.539 27.282  1.00 31.99  ? 225 HIS B CA  1 
ATOM   3944  C  C   . HIS B 1 225 ? 43.020  -27.939 25.928  1.00 31.51  ? 225 HIS B C   1 
ATOM   3945  O  O   . HIS B 1 225 ? 42.737  -28.479 24.853  1.00 29.87  ? 225 HIS B O   1 
ATOM   3946  C  CB  . HIS B 1 225 ? 41.392  -27.875 27.927  1.00 28.16  ? 225 HIS B CB  1 
ATOM   3947  C  CG  . HIS B 1 225 ? 40.203  -27.848 27.074  1.00 22.76  ? 225 HIS B CG  1 
ATOM   3948  N  ND1 . HIS B 1 225 ? 39.664  -29.003 26.581  1.00 24.72  ? 225 HIS B ND1 1 
ATOM   3949  C  CD2 . HIS B 1 225 ? 39.475  -26.842 26.570  1.00 22.16  ? 225 HIS B CD2 1 
ATOM   3950  C  CE1 . HIS B 1 225 ? 38.609  -28.700 25.814  1.00 24.39  ? 225 HIS B CE1 1 
ATOM   3951  N  NE2 . HIS B 1 225 ? 38.440  -27.395 25.843  1.00 22.65  ? 225 HIS B NE2 1 
ATOM   3952  N  N   . VAL B 1 226 ? 43.655  -26.779 25.995  1.00 30.83  ? 226 VAL B N   1 
ATOM   3953  C  CA  . VAL B 1 226 ? 44.044  -26.067 24.790  1.00 29.97  ? 226 VAL B CA  1 
ATOM   3954  C  C   . VAL B 1 226 ? 45.152  -26.819 24.062  1.00 30.18  ? 226 VAL B C   1 
ATOM   3955  O  O   . VAL B 1 226 ? 45.218  -26.767 22.828  1.00 27.11  ? 226 VAL B O   1 
ATOM   3956  C  CB  . VAL B 1 226 ? 44.463  -24.639 25.173  1.00 34.56  ? 226 VAL B CB  1 
ATOM   3957  C  CG1 . VAL B 1 226 ? 45.517  -24.049 24.233  1.00 35.96  ? 226 VAL B CG1 1 
ATOM   3958  C  CG2 . VAL B 1 226 ? 43.225  -23.767 25.365  1.00 34.56  ? 226 VAL B CG2 1 
ATOM   3959  N  N   . ALA B 1 227 ? 46.045  -27.457 24.813  1.00 30.32  ? 227 ALA B N   1 
ATOM   3960  C  CA  . ALA B 1 227 ? 47.076  -28.279 24.213  1.00 35.05  ? 227 ALA B CA  1 
ATOM   3961  C  C   . ALA B 1 227 ? 46.433  -29.402 23.413  1.00 33.94  ? 227 ALA B C   1 
ATOM   3962  O  O   . ALA B 1 227 ? 46.786  -29.597 22.247  1.00 29.86  ? 227 ALA B O   1 
ATOM   3963  C  CB  . ALA B 1 227 ? 48.034  -28.813 25.272  1.00 37.42  ? 227 ALA B CB  1 
ATOM   3964  N  N   . LEU B 1 228 ? 45.466  -30.106 24.011  1.00 30.49  ? 228 LEU B N   1 
ATOM   3965  C  CA  . LEU B 1 228 ? 44.972  -31.296 23.366  1.00 29.82  ? 228 LEU B CA  1 
ATOM   3966  C  C   . LEU B 1 228 ? 43.986  -30.970 22.263  1.00 35.93  ? 228 LEU B C   1 
ATOM   3967  O  O   . LEU B 1 228 ? 43.814  -31.828 21.410  1.00 33.56  ? 228 LEU B O   1 
ATOM   3968  C  CB  . LEU B 1 228 ? 44.353  -32.225 24.380  1.00 30.40  ? 228 LEU B CB  1 
ATOM   3969  C  CG  . LEU B 1 228 ? 45.336  -32.927 25.314  1.00 35.22  ? 228 LEU B CG  1 
ATOM   3970  C  CD1 . LEU B 1 228 ? 44.562  -33.587 26.420  1.00 35.98  ? 228 LEU B CD1 1 
ATOM   3971  C  CD2 . LEU B 1 228 ? 46.025  -33.985 24.540  1.00 37.15  ? 228 LEU B CD2 1 
ATOM   3972  N  N   . THR B 1 229 ? 43.320  -29.789 22.281  1.00 34.30  ? 229 THR B N   1 
ATOM   3973  C  CA  . THR B 1 229 ? 42.316  -29.498 21.260  1.00 32.56  ? 229 THR B CA  1 
ATOM   3974  C  C   . THR B 1 229 ? 42.923  -28.680 20.135  1.00 33.75  ? 229 THR B C   1 
ATOM   3975  O  O   . THR B 1 229 ? 42.185  -28.362 19.236  1.00 42.27  ? 229 THR B O   1 
ATOM   3976  C  CB  . THR B 1 229 ? 41.104  -28.768 21.857  1.00 27.82  ? 229 THR B CB  1 
ATOM   3977  O  OG1 . THR B 1 229 ? 41.468  -27.562 22.541  1.00 22.85  ? 229 THR B OG1 1 
ATOM   3978  C  CG2 . THR B 1 229 ? 40.310  -29.675 22.763  1.00 29.14  ? 229 THR B CG2 1 
ATOM   3979  N  N   . SER B 1 230 ? 44.229  -28.376 20.165  1.00 40.70  ? 230 SER B N   1 
ATOM   3980  C  CA  . SER B 1 230 ? 44.949  -27.826 19.015  1.00 43.50  ? 230 SER B CA  1 
ATOM   3981  C  C   . SER B 1 230 ? 45.424  -28.960 18.123  1.00 43.02  ? 230 SER B C   1 
ATOM   3982  O  O   . SER B 1 230 ? 46.154  -29.814 18.582  1.00 51.06  ? 230 SER B O   1 
ATOM   3983  C  CB  . SER B 1 230 ? 46.099  -27.005 19.440  1.00 40.13  ? 230 SER B CB  1 
ATOM   3984  O  OG  . SER B 1 230 ? 45.644  -25.905 20.206  1.00 44.90  ? 230 SER B OG  1 
ATOM   3985  N  N   . VAL B 1 231 ? 44.960  -29.018 16.880  1.00 46.16  ? 231 VAL B N   1 
ATOM   3986  C  CA  . VAL B 1 231 ? 45.365  -30.098 15.997  1.00 48.12  ? 231 VAL B CA  1 
ATOM   3987  C  C   . VAL B 1 231 ? 45.863  -29.421 14.745  1.00 49.72  ? 231 VAL B C   1 
ATOM   3988  O  O   . VAL B 1 231 ? 45.245  -28.433 14.352  1.00 48.63  ? 231 VAL B O   1 
ATOM   3989  C  CB  . VAL B 1 231 ? 44.268  -31.083 15.600  1.00 51.18  ? 231 VAL B CB  1 
ATOM   3990  C  CG1 . VAL B 1 231 ? 44.943  -32.359 15.161  1.00 57.91  ? 231 VAL B CG1 1 
ATOM   3991  C  CG2 . VAL B 1 231 ? 43.310  -31.381 16.726  1.00 54.04  ? 231 VAL B CG2 1 
ATOM   3992  N  N   . THR B 1 232 ? 46.986  -29.868 14.165  1.00 55.81  ? 232 THR B N   1 
ATOM   3993  C  CA  . THR B 1 232 ? 47.301  -29.424 12.807  1.00 64.10  ? 232 THR B CA  1 
ATOM   3994  C  C   . THR B 1 232 ? 47.039  -30.595 11.843  1.00 70.52  ? 232 THR B C   1 
ATOM   3995  O  O   . THR B 1 232 ? 47.198  -31.769 12.216  1.00 64.62  ? 232 THR B O   1 
ATOM   3996  C  CB  . THR B 1 232 ? 48.702  -28.817 12.693  1.00 52.02  ? 232 THR B CB  1 
ATOM   3997  O  OG1 . THR B 1 232 ? 49.292  -30.077 12.961  1.00 51.75  ? 232 THR B OG1 1 
ATOM   3998  C  CG2 . THR B 1 232 ? 48.935  -27.638 13.625  1.00 50.44  ? 232 THR B CG2 1 
ATOM   3999  N  N   . GLY B 1 233 ? 46.572  -30.258 10.617  1.00 74.40  ? 233 GLY B N   1 
ATOM   4000  C  CA  . GLY B 1 233 ? 46.289  -31.251 9.581   1.00 76.85  ? 233 GLY B CA  1 
ATOM   4001  C  C   . GLY B 1 233 ? 47.546  -31.627 8.785   1.00 85.13  ? 233 GLY B C   1 
ATOM   4002  O  O   . GLY B 1 233 ? 48.621  -31.076 9.049   1.00 78.49  ? 233 GLY B O   1 
ATOM   4003  N  N   . PRO B 1 234 ? 47.492  -32.598 7.837   1.00 87.99  ? 234 PRO B N   1 
ATOM   4004  C  CA  . PRO B 1 234 ? 48.679  -32.930 7.025   1.00 86.09  ? 234 PRO B CA  1 
ATOM   4005  C  C   . PRO B 1 234 ? 49.588  -31.762 6.588   1.00 72.00  ? 234 PRO B C   1 
ATOM   4006  O  O   . PRO B 1 234 ? 50.785  -31.818 6.827   1.00 60.10  ? 234 PRO B O   1 
ATOM   4007  C  CB  . PRO B 1 234 ? 48.082  -33.780 5.860   1.00 91.95  ? 234 PRO B CB  1 
ATOM   4008  C  CG  . PRO B 1 234 ? 46.832  -34.461 6.487   1.00 81.07  ? 234 PRO B CG  1 
ATOM   4009  C  CD  . PRO B 1 234 ? 46.347  -33.504 7.587   1.00 80.74  ? 234 PRO B CD  1 
ATOM   4010  N  N   . ASP B 1 235 ? 49.079  -30.620 6.104   1.00 70.67  ? 235 ASP B N   1 
ATOM   4011  C  CA  . ASP B 1 235 ? 49.982  -29.533 5.714   1.00 86.50  ? 235 ASP B CA  1 
ATOM   4012  C  C   . ASP B 1 235 ? 50.467  -28.591 6.836   1.00 103.06 ? 235 ASP B C   1 
ATOM   4013  O  O   . ASP B 1 235 ? 51.115  -27.587 6.527   1.00 103.71 ? 235 ASP B O   1 
ATOM   4014  C  CB  . ASP B 1 235 ? 49.376  -28.646 4.640   1.00 82.35  ? 235 ASP B CB  1 
ATOM   4015  C  CG  . ASP B 1 235 ? 48.043  -28.023 5.003   1.00 89.24  ? 235 ASP B CG  1 
ATOM   4016  O  OD1 . ASP B 1 235 ? 48.031  -27.103 5.866   1.00 93.91  ? 235 ASP B OD1 1 
ATOM   4017  O  OD2 . ASP B 1 235 ? 47.034  -28.499 4.435   1.00 100.28 ? 235 ASP B OD2 1 
ATOM   4018  N  N   . GLY B 1 236 ? 50.144  -28.813 8.117   1.00 88.95  ? 236 GLY B N   1 
ATOM   4019  C  CA  . GLY B 1 236 ? 50.651  -27.916 9.153   1.00 79.73  ? 236 GLY B CA  1 
ATOM   4020  C  C   . GLY B 1 236 ? 49.760  -26.696 9.452   1.00 80.93  ? 236 GLY B C   1 
ATOM   4021  O  O   . GLY B 1 236 ? 50.076  -25.937 10.353  1.00 78.01  ? 236 GLY B O   1 
ATOM   4022  N  N   . SER B 1 237 ? 48.643  -26.480 8.731   1.00 84.66  ? 237 SER B N   1 
ATOM   4023  C  CA  . SER B 1 237 ? 47.605  -25.544 9.185   1.00 86.81  ? 237 SER B CA  1 
ATOM   4024  C  C   . SER B 1 237 ? 46.763  -26.126 10.340  1.00 75.74  ? 237 SER B C   1 
ATOM   4025  O  O   . SER B 1 237 ? 46.424  -27.328 10.384  1.00 52.29  ? 237 SER B O   1 
ATOM   4026  C  CB  . SER B 1 237 ? 46.680  -25.086 8.048   1.00 68.53  ? 237 SER B CB  1 
ATOM   4027  O  OG  . SER B 1 237 ? 45.956  -26.185 7.503   1.00 56.25  ? 237 SER B OG  1 
ATOM   4028  N  N   . ASP B 1 238 ? 46.357  -25.206 11.227  1.00 66.63  ? 238 ASP B N   1 
ATOM   4029  C  CA  . ASP B 1 238 ? 45.396  -25.470 12.281  1.00 62.85  ? 238 ASP B CA  1 
ATOM   4030  C  C   . ASP B 1 238 ? 44.054  -25.995 11.751  1.00 59.49  ? 238 ASP B C   1 
ATOM   4031  O  O   . ASP B 1 238 ? 43.484  -25.449 10.818  1.00 53.66  ? 238 ASP B O   1 
ATOM   4032  C  CB  . ASP B 1 238 ? 45.309  -24.207 13.112  1.00 62.54  ? 238 ASP B CB  1 
ATOM   4033  C  CG  . ASP B 1 238 ? 46.578  -23.999 13.906  1.00 70.50  ? 238 ASP B CG  1 
ATOM   4034  O  OD1 . ASP B 1 238 ? 46.957  -24.952 14.616  1.00 91.61  ? 238 ASP B OD1 1 
ATOM   4035  O  OD2 . ASP B 1 238 ? 47.195  -22.941 13.763  1.00 69.68  ? 238 ASP B OD2 1 
ATOM   4036  N  N   . LEU B 1 239 ? 43.569  -27.079 12.360  1.00 57.12  ? 239 LEU B N   1 
ATOM   4037  C  CA  . LEU B 1 239 ? 42.222  -27.598 12.182  1.00 53.31  ? 239 LEU B CA  1 
ATOM   4038  C  C   . LEU B 1 239 ? 41.307  -26.977 13.244  1.00 55.26  ? 239 LEU B C   1 
ATOM   4039  O  O   . LEU B 1 239 ? 41.629  -27.019 14.425  1.00 52.90  ? 239 LEU B O   1 
ATOM   4040  C  CB  . LEU B 1 239 ? 42.271  -29.114 12.368  1.00 59.89  ? 239 LEU B CB  1 
ATOM   4041  C  CG  . LEU B 1 239 ? 42.910  -29.936 11.239  1.00 58.76  ? 239 LEU B CG  1 
ATOM   4042  C  CD1 . LEU B 1 239 ? 42.593  -31.382 11.587  1.00 60.15  ? 239 LEU B CD1 1 
ATOM   4043  C  CD2 . LEU B 1 239 ? 42.470  -29.692 9.803   1.00 50.20  ? 239 LEU B CD2 1 
ATOM   4044  N  N   . GLU B 1 240 ? 40.191  -26.393 12.813  1.00 46.34  ? 240 GLU B N   1 
ATOM   4045  C  CA  . GLU B 1 240 ? 39.401  -25.480 13.607  1.00 36.74  ? 240 GLU B CA  1 
ATOM   4046  C  C   . GLU B 1 240 ? 37.944  -25.905 13.567  1.00 33.38  ? 240 GLU B C   1 
ATOM   4047  O  O   . GLU B 1 240 ? 37.463  -26.503 12.607  1.00 25.76  ? 240 GLU B O   1 
ATOM   4048  C  CB  . GLU B 1 240 ? 39.499  -24.055 13.071  1.00 37.22  ? 240 GLU B CB  1 
ATOM   4049  C  CG  . GLU B 1 240 ? 40.915  -23.497 13.050  1.00 39.61  ? 240 GLU B CG  1 
ATOM   4050  C  CD  . GLU B 1 240 ? 40.853  -21.999 13.257  1.00 43.59  ? 240 GLU B CD  1 
ATOM   4051  O  OE1 . GLU B 1 240 ? 40.921  -21.324 12.242  1.00 38.59  ? 240 GLU B OE1 1 
ATOM   4052  O  OE2 . GLU B 1 240 ? 40.638  -21.563 14.414  1.00 61.91  ? 240 GLU B OE2 1 
ATOM   4053  N  N   . ILE B 1 241 ? 37.266  -25.606 14.675  1.00 33.11  ? 241 ILE B N   1 
ATOM   4054  C  CA  . ILE B 1 241 ? 35.831  -25.755 14.770  1.00 29.87  ? 241 ILE B CA  1 
ATOM   4055  C  C   . ILE B 1 241 ? 35.248  -24.467 15.334  1.00 28.47  ? 241 ILE B C   1 
ATOM   4056  O  O   . ILE B 1 241 ? 35.944  -23.594 15.863  1.00 26.29  ? 241 ILE B O   1 
ATOM   4057  C  CB  . ILE B 1 241 ? 35.417  -26.954 15.642  1.00 31.24  ? 241 ILE B CB  1 
ATOM   4058  C  CG1 . ILE B 1 241 ? 35.711  -26.741 17.115  1.00 30.45  ? 241 ILE B CG1 1 
ATOM   4059  C  CG2 . ILE B 1 241 ? 36.052  -28.246 15.129  1.00 36.01  ? 241 ILE B CG2 1 
ATOM   4060  C  CD1 . ILE B 1 241 ? 35.172  -27.896 17.950  1.00 32.59  ? 241 ILE B CD1 1 
ATOM   4061  N  N   . LEU B 1 242 ? 33.917  -24.390 15.238  1.00 29.18  ? 242 LEU B N   1 
ATOM   4062  C  CA  . LEU B 1 242 ? 33.233  -23.260 15.814  1.00 31.80  ? 242 LEU B CA  1 
ATOM   4063  C  C   . LEU B 1 242 ? 32.414  -23.774 16.987  1.00 25.28  ? 242 LEU B C   1 
ATOM   4064  O  O   . LEU B 1 242 ? 31.620  -24.649 16.767  1.00 20.60  ? 242 LEU B O   1 
ATOM   4065  C  CB  . LEU B 1 242 ? 32.339  -22.635 14.765  1.00 36.28  ? 242 LEU B CB  1 
ATOM   4066  C  CG  . LEU B 1 242 ? 31.611  -21.377 15.255  1.00 36.63  ? 242 LEU B CG  1 
ATOM   4067  C  CD1 . LEU B 1 242 ? 32.589  -20.302 15.287  1.00 38.95  ? 242 LEU B CD1 1 
ATOM   4068  C  CD2 . LEU B 1 242 ? 30.512  -20.937 14.384  1.00 35.42  ? 242 LEU B CD2 1 
ATOM   4069  N  N   . ARG B 1 243 ? 32.623  -23.207 18.173  1.00 24.26  ? 243 ARG B N   1 
ATOM   4070  C  CA  . ARG B 1 243 ? 31.938  -23.669 19.381  1.00 28.34  ? 243 ARG B CA  1 
ATOM   4071  C  C   . ARG B 1 243 ? 31.018  -22.599 19.925  1.00 24.21  ? 243 ARG B C   1 
ATOM   4072  O  O   . ARG B 1 243 ? 31.266  -21.451 19.688  1.00 23.59  ? 243 ARG B O   1 
ATOM   4073  C  CB  . ARG B 1 243 ? 32.930  -23.997 20.501  1.00 29.42  ? 243 ARG B CB  1 
ATOM   4074  C  CG  . ARG B 1 243 ? 33.883  -25.146 20.172  1.00 26.45  ? 243 ARG B CG  1 
ATOM   4075  C  CD  . ARG B 1 243 ? 34.999  -25.175 21.216  1.00 28.11  ? 243 ARG B CD  1 
ATOM   4076  N  NE  . ARG B 1 243 ? 35.950  -24.109 20.902  1.00 28.11  ? 243 ARG B NE  1 
ATOM   4077  C  CZ  . ARG B 1 243 ? 36.247  -23.088 21.686  1.00 33.03  ? 243 ARG B CZ  1 
ATOM   4078  N  NH1 . ARG B 1 243 ? 35.789  -23.079 22.928  1.00 33.35  ? 243 ARG B NH1 1 
ATOM   4079  N  NH2 . ARG B 1 243 ? 37.031  -22.099 21.216  1.00 37.65  ? 243 ARG B NH2 1 
ATOM   4080  N  N   . ASP B 1 244 ? 29.963  -22.988 20.625  1.00 27.22  ? 244 ASP B N   1 
ATOM   4081  C  CA  . ASP B 1 244 ? 29.063  -22.035 21.269  1.00 30.87  ? 244 ASP B CA  1 
ATOM   4082  C  C   . ASP B 1 244 ? 28.567  -22.625 22.590  1.00 26.66  ? 244 ASP B C   1 
ATOM   4083  O  O   . ASP B 1 244 ? 27.387  -22.686 22.834  1.00 27.03  ? 244 ASP B O   1 
ATOM   4084  C  CB  . ASP B 1 244 ? 27.971  -21.526 20.342  1.00 27.15  ? 244 ASP B CB  1 
ATOM   4085  C  CG  . ASP B 1 244 ? 27.420  -20.170 20.752  1.00 33.21  ? 244 ASP B CG  1 
ATOM   4086  O  OD1 . ASP B 1 244 ? 27.900  -19.586 21.760  1.00 30.70  ? 244 ASP B OD1 1 
ATOM   4087  O  OD2 . ASP B 1 244 ? 26.486  -19.691 20.069  1.00 39.50  ? 244 ASP B OD2 1 
ATOM   4088  N  N   . ASN B 1 245 ? 29.508  -23.016 23.429  1.00 22.33  ? 245 ASN B N   1 
ATOM   4089  C  CA  . ASN B 1 245 ? 29.243  -23.652 24.696  1.00 25.42  ? 245 ASN B CA  1 
ATOM   4090  C  C   . ASN B 1 245 ? 28.400  -22.722 25.570  1.00 23.62  ? 245 ASN B C   1 
ATOM   4091  O  O   . ASN B 1 245 ? 28.703  -21.530 25.668  1.00 24.56  ? 245 ASN B O   1 
ATOM   4092  C  CB  . ASN B 1 245 ? 30.533  -23.944 25.478  1.00 26.79  ? 245 ASN B CB  1 
ATOM   4093  C  CG  . ASN B 1 245 ? 31.462  -24.851 24.725  1.00 32.24  ? 245 ASN B CG  1 
ATOM   4094  O  OD1 . ASN B 1 245 ? 31.031  -25.498 23.741  1.00 33.04  ? 245 ASN B OD1 1 
ATOM   4095  N  ND2 . ASN B 1 245 ? 32.741  -24.793 25.106  1.00 36.32  ? 245 ASN B ND2 1 
ATOM   4096  N  N   . MET B 1 246 ? 27.407  -23.304 26.251  1.00 25.21  ? 246 MET B N   1 
ATOM   4097  C  CA  . MET B 1 246 ? 26.531  -22.577 27.157  1.00 25.06  ? 246 MET B CA  1 
ATOM   4098  C  C   . MET B 1 246 ? 26.491  -23.237 28.525  1.00 23.85  ? 246 MET B C   1 
ATOM   4099  O  O   . MET B 1 246 ? 26.220  -24.419 28.658  1.00 22.74  ? 246 MET B O   1 
ATOM   4100  C  CB  . MET B 1 246 ? 25.101  -22.523 26.626  1.00 28.13  ? 246 MET B CB  1 
ATOM   4101  C  CG  . MET B 1 246 ? 24.960  -21.708 25.377  1.00 31.57  ? 246 MET B CG  1 
ATOM   4102  S  SD  . MET B 1 246 ? 25.405  -19.973 25.556  1.00 31.55  ? 246 MET B SD  1 
ATOM   4103  C  CE  . MET B 1 246 ? 23.840  -19.453 26.197  1.00 34.97  ? 246 MET B CE  1 
ATOM   4104  N  N   . PRO B 1 247 ? 26.678  -22.457 29.599  1.00 22.51  ? 247 PRO B N   1 
ATOM   4105  C  CA  . PRO B 1 247 ? 26.321  -22.869 30.951  1.00 22.46  ? 247 PRO B CA  1 
ATOM   4106  C  C   . PRO B 1 247 ? 24.850  -23.148 31.092  1.00 22.95  ? 247 PRO B C   1 
ATOM   4107  O  O   . PRO B 1 247 ? 24.012  -22.517 30.423  1.00 24.57  ? 247 PRO B O   1 
ATOM   4108  C  CB  . PRO B 1 247 ? 26.642  -21.671 31.811  1.00 22.69  ? 247 PRO B CB  1 
ATOM   4109  C  CG  . PRO B 1 247 ? 27.605  -20.899 30.972  1.00 22.25  ? 247 PRO B CG  1 
ATOM   4110  C  CD  . PRO B 1 247 ? 27.160  -21.085 29.552  1.00 23.36  ? 247 PRO B CD  1 
ATOM   4111  N  N   . PHE B 1 248 ? 24.556  -24.063 32.000  1.00 23.86  ? 248 PHE B N   1 
ATOM   4112  C  CA  . PHE B 1 248 ? 23.179  -24.301 32.388  1.00 23.32  ? 248 PHE B CA  1 
ATOM   4113  C  C   . PHE B 1 248 ? 23.247  -24.871 33.787  1.00 25.44  ? 248 PHE B C   1 
ATOM   4114  O  O   . PHE B 1 248 ? 24.298  -25.355 34.235  1.00 25.64  ? 248 PHE B O   1 
ATOM   4115  C  CB  . PHE B 1 248 ? 22.442  -25.270 31.469  1.00 22.59  ? 248 PHE B CB  1 
ATOM   4116  C  CG  . PHE B 1 248 ? 22.987  -26.682 31.529  1.00 23.10  ? 248 PHE B CG  1 
ATOM   4117  C  CD1 . PHE B 1 248 ? 24.087  -27.069 30.763  1.00 25.57  ? 248 PHE B CD1 1 
ATOM   4118  C  CD2 . PHE B 1 248 ? 22.405  -27.628 32.363  1.00 25.48  ? 248 PHE B CD2 1 
ATOM   4119  C  CE1 . PHE B 1 248 ? 24.608  -28.353 30.872  1.00 24.36  ? 248 PHE B CE1 1 
ATOM   4120  C  CE2 . PHE B 1 248 ? 22.961  -28.897 32.505  1.00 23.47  ? 248 PHE B CE2 1 
ATOM   4121  C  CZ  . PHE B 1 248 ? 24.031  -29.260 31.727  1.00 26.66  ? 248 PHE B CZ  1 
ATOM   4122  N  N   . GLY B 1 249 ? 22.107  -24.857 34.457  1.00 23.35  ? 249 GLY B N   1 
ATOM   4123  C  CA  . GLY B 1 249 ? 22.053  -25.622 35.675  1.00 24.38  ? 249 GLY B CA  1 
ATOM   4124  C  C   . GLY B 1 249 ? 20.848  -25.380 36.544  1.00 22.12  ? 249 GLY B C   1 
ATOM   4125  O  O   . GLY B 1 249 ? 19.915  -24.651 36.223  1.00 21.67  ? 249 GLY B O   1 
ATOM   4126  N  N   . SER B 1 250 ? 20.957  -25.984 37.720  1.00 27.04  ? 250 SER B N   1 
ATOM   4127  C  CA  . SER B 1 250 ? 19.921  -25.834 38.733  1.00 31.33  ? 250 SER B CA  1 
ATOM   4128  C  C   . SER B 1 250 ? 20.591  -25.875 40.108  1.00 28.41  ? 250 SER B C   1 
ATOM   4129  O  O   . SER B 1 250 ? 21.339  -26.796 40.444  1.00 26.49  ? 250 SER B O   1 
ATOM   4130  C  CB  . SER B 1 250 ? 18.886  -26.922 38.476  1.00 36.52  ? 250 SER B CB  1 
ATOM   4131  O  OG  . SER B 1 250 ? 18.387  -27.450 39.680  1.00 47.30  ? 250 SER B OG  1 
ATOM   4132  N  N   . VAL B 1 251 ? 20.384  -24.842 40.907  1.00 28.87  ? 251 VAL B N   1 
ATOM   4133  C  CA  . VAL B 1 251 ? 21.089  -24.712 42.184  1.00 28.75  ? 251 VAL B CA  1 
ATOM   4134  C  C   . VAL B 1 251 ? 20.560  -25.721 43.197  1.00 30.45  ? 251 VAL B C   1 
ATOM   4135  O  O   . VAL B 1 251 ? 21.328  -26.261 43.975  1.00 33.41  ? 251 VAL B O   1 
ATOM   4136  C  CB  . VAL B 1 251 ? 20.726  -23.263 42.506  1.00 35.50  ? 251 VAL B CB  1 
ATOM   4137  C  CG1 . VAL B 1 251 ? 20.688  -22.981 43.960  1.00 38.87  ? 251 VAL B CG1 1 
ATOM   4138  C  CG2 . VAL B 1 251 ? 21.610  -22.282 41.782  1.00 41.60  ? 251 VAL B CG2 1 
ATOM   4139  N  N   . GLY B 1 252 ? 19.233  -25.979 43.115  1.00 29.34  ? 252 GLY B N   1 
ATOM   4140  C  CA  . GLY B 1 252 ? 18.489  -26.883 43.965  1.00 30.18  ? 252 GLY B CA  1 
ATOM   4141  C  C   . GLY B 1 252 ? 18.994  -28.302 43.817  1.00 32.23  ? 252 GLY B C   1 
ATOM   4142  O  O   . GLY B 1 252 ? 19.237  -28.965 44.787  1.00 35.43  ? 252 GLY B O   1 
ATOM   4143  N  N   . ARG B 1 253 ? 19.208  -28.771 42.605  1.00 35.42  ? 253 ARG B N   1 
ATOM   4144  C  CA  . ARG B 1 253 ? 19.679  -30.146 42.385  1.00 36.35  ? 253 ARG B CA  1 
ATOM   4145  C  C   . ARG B 1 253 ? 21.205  -30.207 42.267  1.00 36.56  ? 253 ARG B C   1 
ATOM   4146  O  O   . ARG B 1 253 ? 21.746  -31.239 41.940  1.00 33.50  ? 253 ARG B O   1 
ATOM   4147  C  CB  . ARG B 1 253 ? 19.084  -30.758 41.116  1.00 33.55  ? 253 ARG B CB  1 
ATOM   4148  C  CG  . ARG B 1 253 ? 17.567  -30.797 41.171  1.00 43.80  ? 253 ARG B CG  1 
ATOM   4149  C  CD  . ARG B 1 253 ? 17.064  -31.908 40.293  1.00 56.75  ? 253 ARG B CD  1 
ATOM   4150  N  NE  . ARG B 1 253 ? 17.639  -31.699 38.964  1.00 71.61  ? 253 ARG B NE  1 
ATOM   4151  C  CZ  . ARG B 1 253 ? 17.476  -30.615 38.203  1.00 77.27  ? 253 ARG B CZ  1 
ATOM   4152  N  NH1 . ARG B 1 253 ? 16.482  -29.741 38.418  1.00 73.90  ? 253 ARG B NH1 1 
ATOM   4153  N  NH2 . ARG B 1 253 ? 18.319  -30.447 37.197  1.00 79.42  ? 253 ARG B NH2 1 
ATOM   4154  N  N   . GLU B 1 254 ? 21.916  -29.118 42.586  1.00 41.56  ? 254 GLU B N   1 
ATOM   4155  C  CA  . GLU B 1 254 ? 23.357  -29.038 42.417  1.00 45.69  ? 254 GLU B CA  1 
ATOM   4156  C  C   . GLU B 1 254 ? 23.838  -29.543 41.056  1.00 42.84  ? 254 GLU B C   1 
ATOM   4157  O  O   . GLU B 1 254 ? 24.852  -30.225 41.019  1.00 33.77  ? 254 GLU B O   1 
ATOM   4158  C  CB  . GLU B 1 254 ? 24.050  -29.882 43.465  1.00 49.80  ? 254 GLU B CB  1 
ATOM   4159  C  CG  . GLU B 1 254 ? 23.854  -29.326 44.865  1.00 64.16  ? 254 GLU B CG  1 
ATOM   4160  C  CD  . GLU B 1 254 ? 24.576  -30.191 45.861  1.00 69.14  ? 254 GLU B CD  1 
ATOM   4161  O  OE1 . GLU B 1 254 ? 25.827  -30.173 45.744  1.00 61.88  ? 254 GLU B OE1 1 
ATOM   4162  O  OE2 . GLU B 1 254 ? 23.878  -30.880 46.649  1.00 66.90  ? 254 GLU B OE2 1 
ATOM   4163  N  N   . GLU B 1 255 ? 23.122  -29.194 39.954  1.00 34.69  ? 255 GLU B N   1 
ATOM   4164  C  CA  . GLU B 1 255 ? 23.624  -29.393 38.618  1.00 33.11  ? 255 GLU B CA  1 
ATOM   4165  C  C   . GLU B 1 255 ? 24.262  -28.121 38.082  1.00 29.10  ? 255 GLU B C   1 
ATOM   4166  O  O   . GLU B 1 255 ? 23.602  -27.088 37.984  1.00 28.87  ? 255 GLU B O   1 
ATOM   4167  C  CB  . GLU B 1 255 ? 22.512  -29.771 37.676  1.00 40.72  ? 255 GLU B CB  1 
ATOM   4168  C  CG  . GLU B 1 255 ? 22.101  -31.221 37.864  1.00 52.71  ? 255 GLU B CG  1 
ATOM   4169  C  CD  . GLU B 1 255 ? 21.083  -31.627 36.807  1.00 63.52  ? 255 GLU B CD  1 
ATOM   4170  O  OE1 . GLU B 1 255 ? 20.812  -30.791 35.856  1.00 53.21  ? 255 GLU B OE1 1 
ATOM   4171  O  OE2 . GLU B 1 255 ? 20.565  -32.766 36.993  1.00 58.03  ? 255 GLU B OE2 1 
ATOM   4172  N  N   . PHE B 1 256 ? 25.549  -28.213 37.757  1.00 25.06  ? 256 PHE B N   1 
ATOM   4173  C  CA  . PHE B 1 256 ? 26.238  -27.108 37.114  1.00 26.83  ? 256 PHE B CA  1 
ATOM   4174  C  C   . PHE B 1 256 ? 26.928  -27.674 35.885  1.00 25.71  ? 256 PHE B C   1 
ATOM   4175  O  O   . PHE B 1 256 ? 27.696  -28.613 36.016  1.00 28.11  ? 256 PHE B O   1 
ATOM   4176  C  CB  . PHE B 1 256 ? 27.256  -26.432 38.027  1.00 28.01  ? 256 PHE B CB  1 
ATOM   4177  C  CG  . PHE B 1 256 ? 26.657  -26.027 39.354  1.00 30.70  ? 256 PHE B CG  1 
ATOM   4178  C  CD1 . PHE B 1 256 ? 25.980  -24.831 39.471  1.00 34.19  ? 256 PHE B CD1 1 
ATOM   4179  C  CD2 . PHE B 1 256 ? 26.787  -26.851 40.477  1.00 34.37  ? 256 PHE B CD2 1 
ATOM   4180  C  CE1 . PHE B 1 256 ? 25.490  -24.430 40.698  1.00 36.19  ? 256 PHE B CE1 1 
ATOM   4181  C  CE2 . PHE B 1 256 ? 26.226  -26.475 41.688  1.00 35.27  ? 256 PHE B CE2 1 
ATOM   4182  C  CZ  . PHE B 1 256 ? 25.623  -25.259 41.799  1.00 37.39  ? 256 PHE B CZ  1 
ATOM   4183  N  N   . GLY B 1 257 ? 26.578  -27.148 34.713  1.00 27.85  ? 257 GLY B N   1 
ATOM   4184  C  CA  . GLY B 1 257 ? 26.865  -27.830 33.465  1.00 28.28  ? 257 GLY B CA  1 
ATOM   4185  C  C   . GLY B 1 257 ? 27.431  -26.885 32.404  1.00 24.99  ? 257 GLY B C   1 
ATOM   4186  O  O   . GLY B 1 257 ? 27.361  -25.661 32.502  1.00 22.32  ? 257 GLY B O   1 
ATOM   4187  N  N   . THR B 1 258 ? 28.037  -27.513 31.399  1.00 25.57  ? 258 THR B N   1 
ATOM   4188  C  CA  . THR B 1 258 ? 28.406  -26.835 30.180  1.00 24.07  ? 258 THR B CA  1 
ATOM   4189  C  C   . THR B 1 258 ? 27.791  -27.637 29.052  1.00 22.47  ? 258 THR B C   1 
ATOM   4190  O  O   . THR B 1 258 ? 27.968  -28.817 29.002  1.00 23.47  ? 258 THR B O   1 
ATOM   4191  C  CB  . THR B 1 258 ? 29.917  -26.684 30.078  1.00 27.08  ? 258 THR B CB  1 
ATOM   4192  O  OG1 . THR B 1 258 ? 30.349  -25.637 30.974  1.00 32.73  ? 258 THR B OG1 1 
ATOM   4193  C  CG2 . THR B 1 258 ? 30.284  -26.293 28.648  1.00 36.05  ? 258 THR B CG2 1 
ATOM   4194  N  N   . TYR B 1 259 ? 26.991  -27.013 28.207  1.00 22.51  ? 259 TYR B N   1 
ATOM   4195  C  CA  . TYR B 1 259 ? 26.462  -27.679 27.041  1.00 22.95  ? 259 TYR B CA  1 
ATOM   4196  C  C   . TYR B 1 259 ? 27.407  -27.352 25.876  1.00 23.17  ? 259 TYR B C   1 
ATOM   4197  O  O   . TYR B 1 259 ? 27.450  -26.221 25.402  1.00 25.51  ? 259 TYR B O   1 
ATOM   4198  C  CB  . TYR B 1 259 ? 24.991  -27.319 26.784  1.00 23.08  ? 259 TYR B CB  1 
ATOM   4199  C  CG  . TYR B 1 259 ? 24.269  -28.309 25.876  1.00 25.91  ? 259 TYR B CG  1 
ATOM   4200  C  CD1 . TYR B 1 259 ? 24.411  -28.250 24.494  1.00 29.97  ? 259 TYR B CD1 1 
ATOM   4201  C  CD2 . TYR B 1 259 ? 23.442  -29.294 26.383  1.00 27.63  ? 259 TYR B CD2 1 
ATOM   4202  C  CE1 . TYR B 1 259 ? 23.773  -29.145 23.652  1.00 29.53  ? 259 TYR B CE1 1 
ATOM   4203  C  CE2 . TYR B 1 259 ? 22.797  -30.196 25.551  1.00 31.56  ? 259 TYR B CE2 1 
ATOM   4204  C  CZ  . TYR B 1 259 ? 22.969  -30.117 24.183  1.00 28.06  ? 259 TYR B CZ  1 
ATOM   4205  O  OH  . TYR B 1 259 ? 22.430  -31.008 23.343  1.00 26.41  ? 259 TYR B OH  1 
ATOM   4206  N  N   . PHE B 1 260 ? 28.155  -28.363 25.415  1.00 25.17  ? 260 PHE B N   1 
ATOM   4207  C  CA  . PHE B 1 260 ? 29.099  -28.249 24.312  1.00 24.32  ? 260 PHE B CA  1 
ATOM   4208  C  C   . PHE B 1 260 ? 28.383  -28.451 22.989  1.00 23.13  ? 260 PHE B C   1 
ATOM   4209  O  O   . PHE B 1 260 ? 27.662  -29.413 22.825  1.00 20.60  ? 260 PHE B O   1 
ATOM   4210  C  CB  . PHE B 1 260 ? 30.165  -29.337 24.404  1.00 27.35  ? 260 PHE B CB  1 
ATOM   4211  C  CG  . PHE B 1 260 ? 31.078  -29.343 23.201  1.00 25.79  ? 260 PHE B CG  1 
ATOM   4212  C  CD1 . PHE B 1 260 ? 32.110  -28.418 23.090  1.00 27.42  ? 260 PHE B CD1 1 
ATOM   4213  C  CD2 . PHE B 1 260 ? 30.869  -30.279 22.188  1.00 27.32  ? 260 PHE B CD2 1 
ATOM   4214  C  CE1 . PHE B 1 260 ? 32.938  -28.450 21.974  1.00 26.89  ? 260 PHE B CE1 1 
ATOM   4215  C  CE2 . PHE B 1 260 ? 31.650  -30.263 21.028  1.00 25.54  ? 260 PHE B CE2 1 
ATOM   4216  C  CZ  . PHE B 1 260 ? 32.696  -29.361 20.934  1.00 27.65  ? 260 PHE B CZ  1 
ATOM   4217  N  N   . ILE B 1 261 ? 28.576  -27.529 22.060  1.00 21.10  ? 261 ILE B N   1 
ATOM   4218  C  CA  . ILE B 1 261 ? 28.184  -27.714 20.673  1.00 23.54  ? 261 ILE B CA  1 
ATOM   4219  C  C   . ILE B 1 261 ? 29.322  -27.180 19.803  1.00 23.51  ? 261 ILE B C   1 
ATOM   4220  O  O   . ILE B 1 261 ? 29.842  -26.083 20.023  1.00 24.04  ? 261 ILE B O   1 
ATOM   4221  C  CB  . ILE B 1 261 ? 26.831  -27.054 20.330  1.00 28.94  ? 261 ILE B CB  1 
ATOM   4222  C  CG1 . ILE B 1 261 ? 26.417  -27.433 18.921  1.00 27.53  ? 261 ILE B CG1 1 
ATOM   4223  C  CG2 . ILE B 1 261 ? 26.830  -25.521 20.551  1.00 31.37  ? 261 ILE B CG2 1 
ATOM   4224  C  CD1 . ILE B 1 261 ? 24.948  -27.185 18.654  1.00 29.46  ? 261 ILE B CD1 1 
ATOM   4225  N  N   . GLY B 1 262 ? 29.756  -28.045 18.897  1.00 24.63  ? 262 GLY B N   1 
ATOM   4226  C  CA  . GLY B 1 262 ? 30.804  -27.746 17.962  1.00 25.58  ? 262 GLY B CA  1 
ATOM   4227  C  C   . GLY B 1 262 ? 30.353  -28.010 16.531  1.00 26.29  ? 262 GLY B C   1 
ATOM   4228  O  O   . GLY B 1 262 ? 29.908  -29.112 16.217  1.00 27.33  ? 262 GLY B O   1 
ATOM   4229  N  N   . TYR B 1 263 ? 30.584  -26.996 15.665  1.00 30.17  ? 263 TYR B N   1 
ATOM   4230  C  CA  . TYR B 1 263 ? 30.306  -27.097 14.238  1.00 28.94  ? 263 TYR B CA  1 
ATOM   4231  C  C   . TYR B 1 263 ? 31.597  -27.197 13.445  1.00 27.54  ? 263 TYR B C   1 
ATOM   4232  O  O   . TYR B 1 263 ? 32.551  -26.507 13.769  1.00 25.67  ? 263 TYR B O   1 
ATOM   4233  C  CB  . TYR B 1 263 ? 29.542  -25.868 13.791  1.00 26.08  ? 263 TYR B CB  1 
ATOM   4234  C  CG  . TYR B 1 263 ? 28.118  -25.783 14.291  1.00 23.29  ? 263 TYR B CG  1 
ATOM   4235  C  CD1 . TYR B 1 263 ? 27.088  -26.358 13.570  1.00 23.18  ? 263 TYR B CD1 1 
ATOM   4236  C  CD2 . TYR B 1 263 ? 27.824  -25.059 15.431  1.00 21.39  ? 263 TYR B CD2 1 
ATOM   4237  C  CE1 . TYR B 1 263 ? 25.779  -26.213 13.960  1.00 26.19  ? 263 TYR B CE1 1 
ATOM   4238  C  CE2 . TYR B 1 263 ? 26.522  -24.919 15.851  1.00 26.29  ? 263 TYR B CE2 1 
ATOM   4239  C  CZ  . TYR B 1 263 ? 25.492  -25.518 15.132  1.00 29.42  ? 263 TYR B CZ  1 
ATOM   4240  O  OH  . TYR B 1 263 ? 24.201  -25.354 15.585  1.00 27.84  ? 263 TYR B OH  1 
ATOM   4241  N  N   . ALA B 1 264 ? 31.594  -28.072 12.434  1.00 27.73  ? 264 ALA B N   1 
ATOM   4242  C  CA  . ALA B 1 264 ? 32.752  -28.275 11.561  1.00 33.80  ? 264 ALA B CA  1 
ATOM   4243  C  C   . ALA B 1 264 ? 32.274  -28.761 10.193  1.00 29.18  ? 264 ALA B C   1 
ATOM   4244  O  O   . ALA B 1 264 ? 31.212  -29.425 10.146  1.00 24.67  ? 264 ALA B O   1 
ATOM   4245  C  CB  . ALA B 1 264 ? 33.670  -29.304 12.180  1.00 36.09  ? 264 ALA B CB  1 
ATOM   4246  N  N   . ARG B 1 265 ? 33.076  -28.476 9.137   1.00 27.80  ? 265 ARG B N   1 
ATOM   4247  C  CA  . ARG B 1 265 ? 32.700  -28.888 7.780   1.00 32.77  ? 265 ARG B CA  1 
ATOM   4248  C  C   . ARG B 1 265 ? 32.787  -30.410 7.586   1.00 30.00  ? 265 ARG B C   1 
ATOM   4249  O  O   . ARG B 1 265 ? 32.192  -30.964 6.687   1.00 26.01  ? 265 ARG B O   1 
ATOM   4250  C  CB  . ARG B 1 265 ? 33.521  -28.185 6.692   1.00 41.59  ? 265 ARG B CB  1 
ATOM   4251  C  CG  . ARG B 1 265 ? 34.973  -28.594 6.589   1.00 52.38  ? 265 ARG B CG  1 
ATOM   4252  C  CD  . ARG B 1 265 ? 35.682  -27.705 5.583   1.00 56.48  ? 265 ARG B CD  1 
ATOM   4253  N  NE  . ARG B 1 265 ? 35.133  -27.850 4.218   1.00 63.96  ? 265 ARG B NE  1 
ATOM   4254  C  CZ  . ARG B 1 265 ? 35.309  -26.955 3.232   1.00 57.93  ? 265 ARG B CZ  1 
ATOM   4255  N  NH1 . ARG B 1 265 ? 35.886  -25.777 3.439   1.00 52.77  ? 265 ARG B NH1 1 
ATOM   4256  N  NH2 . ARG B 1 265 ? 34.832  -27.196 2.040   1.00 58.57  ? 265 ARG B NH2 1 
ATOM   4257  N  N   . THR B 1 266 ? 33.540  -31.110 8.434   1.00 32.30  ? 266 THR B N   1 
ATOM   4258  C  CA  . THR B 1 266 ? 33.493  -32.570 8.475   1.00 34.22  ? 266 THR B CA  1 
ATOM   4259  C  C   . THR B 1 266 ? 33.627  -33.009 9.935   1.00 32.08  ? 266 THR B C   1 
ATOM   4260  O  O   . THR B 1 266 ? 34.381  -32.421 10.719  1.00 32.35  ? 266 THR B O   1 
ATOM   4261  C  CB  . THR B 1 266 ? 34.628  -33.160 7.635   1.00 35.12  ? 266 THR B CB  1 
ATOM   4262  O  OG1 . THR B 1 266 ? 34.741  -34.533 8.008   1.00 39.65  ? 266 THR B OG1 1 
ATOM   4263  C  CG2 . THR B 1 266 ? 35.970  -32.533 7.972   1.00 34.59  ? 266 THR B CG2 1 
ATOM   4264  N  N   . PRO B 1 267 ? 32.955  -34.087 10.346  1.00 29.96  ? 267 PRO B N   1 
ATOM   4265  C  CA  . PRO B 1 267 ? 33.086  -34.535 11.721  1.00 34.43  ? 267 PRO B CA  1 
ATOM   4266  C  C   . PRO B 1 267 ? 34.459  -35.064 12.098  1.00 35.11  ? 267 PRO B C   1 
ATOM   4267  O  O   . PRO B 1 267 ? 34.726  -35.154 13.293  1.00 37.93  ? 267 PRO B O   1 
ATOM   4268  C  CB  . PRO B 1 267 ? 32.012  -35.581 11.910  1.00 33.30  ? 267 PRO B CB  1 
ATOM   4269  C  CG  . PRO B 1 267 ? 31.642  -35.979 10.501  1.00 33.58  ? 267 PRO B CG  1 
ATOM   4270  C  CD  . PRO B 1 267 ? 32.031  -34.891 9.532   1.00 34.01  ? 267 PRO B CD  1 
ATOM   4271  N  N   . GLU B 1 268 ? 35.329  -35.341 11.108  1.00 41.20  ? 268 GLU B N   1 
ATOM   4272  C  CA  . GLU B 1 268 ? 36.653  -35.943 11.351  1.00 44.72  ? 268 GLU B CA  1 
ATOM   4273  C  C   . GLU B 1 268 ? 37.462  -35.017 12.295  1.00 34.44  ? 268 GLU B C   1 
ATOM   4274  O  O   . GLU B 1 268 ? 38.153  -35.461 13.215  1.00 34.03  ? 268 GLU B O   1 
ATOM   4275  C  CB  . GLU B 1 268 ? 37.357  -36.510 10.084  1.00 47.38  ? 268 GLU B CB  1 
ATOM   4276  C  CG  . GLU B 1 268 ? 37.574  -38.041 10.007  1.00 39.56  ? 268 GLU B CG  1 
ATOM   4277  N  N   . VAL B 1 269 ? 37.313  -33.704 12.105  1.00 33.07  ? 269 VAL B N   1 
ATOM   4278  C  CA  . VAL B 1 269 ? 38.046  -32.732 12.904  1.00 35.94  ? 269 VAL B CA  1 
ATOM   4279  C  C   . VAL B 1 269 ? 37.603  -32.815 14.363  1.00 33.87  ? 269 VAL B C   1 
ATOM   4280  O  O   . VAL B 1 269 ? 38.446  -32.958 15.236  1.00 37.03  ? 269 VAL B O   1 
ATOM   4281  C  CB  . VAL B 1 269 ? 37.821  -31.299 12.385  1.00 42.55  ? 269 VAL B CB  1 
ATOM   4282  C  CG1 . VAL B 1 269 ? 38.486  -30.256 13.274  1.00 33.45  ? 269 VAL B CG1 1 
ATOM   4283  C  CG2 . VAL B 1 269 ? 38.233  -31.177 10.915  1.00 49.35  ? 269 VAL B CG2 1 
ATOM   4284  N  N   . THR B 1 270 ? 36.291  -32.703 14.605  1.00 35.39  ? 270 THR B N   1 
ATOM   4285  C  CA  . THR B 1 270 ? 35.727  -32.754 15.946  1.00 32.96  ? 270 THR B CA  1 
ATOM   4286  C  C   . THR B 1 270 ? 36.054  -34.091 16.614  1.00 33.74  ? 270 THR B C   1 
ATOM   4287  O  O   . THR B 1 270 ? 36.412  -34.102 17.808  1.00 31.63  ? 270 THR B O   1 
ATOM   4288  C  CB  . THR B 1 270 ? 34.223  -32.547 15.887  1.00 31.16  ? 270 THR B CB  1 
ATOM   4289  O  OG1 . THR B 1 270 ? 33.937  -31.362 15.158  1.00 34.46  ? 270 THR B OG1 1 
ATOM   4290  C  CG2 . THR B 1 270 ? 33.650  -32.352 17.269  1.00 34.08  ? 270 THR B CG2 1 
ATOM   4291  N  N   . GLU B 1 271 ? 35.931  -35.199 15.855  1.00 32.44  ? 271 GLU B N   1 
ATOM   4292  C  CA  . GLU B 1 271 ? 36.152  -36.532 16.420  1.00 30.26  ? 271 GLU B CA  1 
ATOM   4293  C  C   . GLU B 1 271 ? 37.619  -36.698 16.805  1.00 35.98  ? 271 GLU B C   1 
ATOM   4294  O  O   . GLU B 1 271 ? 37.915  -37.405 17.760  1.00 33.07  ? 271 GLU B O   1 
ATOM   4295  C  CB  . GLU B 1 271 ? 35.735  -37.618 15.440  1.00 29.54  ? 271 GLU B CB  1 
ATOM   4296  C  CG  . GLU B 1 271 ? 34.220  -37.739 15.345  1.00 36.13  ? 271 GLU B CG  1 
ATOM   4297  C  CD  . GLU B 1 271 ? 33.571  -38.559 14.245  1.00 39.15  ? 271 GLU B CD  1 
ATOM   4298  O  OE1 . GLU B 1 271 ? 34.246  -38.749 13.239  1.00 51.26  ? 271 GLU B OE1 1 
ATOM   4299  O  OE2 . GLU B 1 271 ? 32.398  -38.939 14.352  1.00 39.94  ? 271 GLU B OE2 1 
ATOM   4300  N  N   . THR B 1 272 ? 38.550  -36.040 16.079  1.00 32.93  ? 272 THR B N   1 
ATOM   4301  C  CA  . THR B 1 272 ? 39.954  -36.232 16.390  1.00 27.33  ? 272 THR B CA  1 
ATOM   4302  C  C   . THR B 1 272 ? 40.241  -35.544 17.703  1.00 32.54  ? 272 THR B C   1 
ATOM   4303  O  O   . THR B 1 272 ? 40.983  -36.073 18.526  1.00 39.48  ? 272 THR B O   1 
ATOM   4304  C  CB  . THR B 1 272 ? 40.787  -35.637 15.272  1.00 29.44  ? 272 THR B CB  1 
ATOM   4305  O  OG1 . THR B 1 272 ? 40.578  -36.501 14.169  1.00 26.37  ? 272 THR B OG1 1 
ATOM   4306  C  CG2 . THR B 1 272 ? 42.260  -35.605 15.549  1.00 28.52  ? 272 THR B CG2 1 
ATOM   4307  N  N   . MET B 1 273 ? 39.677  -34.350 17.888  1.00 32.37  ? 273 MET B N   1 
ATOM   4308  C  CA  . MET B 1 273 ? 39.837  -33.599 19.131  1.00 29.93  ? 273 MET B CA  1 
ATOM   4309  C  C   . MET B 1 273 ? 39.290  -34.427 20.292  1.00 30.54  ? 273 MET B C   1 
ATOM   4310  O  O   . MET B 1 273 ? 39.886  -34.509 21.372  1.00 33.96  ? 273 MET B O   1 
ATOM   4311  C  CB  . MET B 1 273 ? 39.076  -32.266 19.045  1.00 31.97  ? 273 MET B CB  1 
ATOM   4312  C  CG  . MET B 1 273 ? 39.722  -31.216 18.135  1.00 33.61  ? 273 MET B CG  1 
ATOM   4313  S  SD  . MET B 1 273 ? 38.652  -29.784 17.905  1.00 34.26  ? 273 MET B SD  1 
ATOM   4314  C  CE  . MET B 1 273 ? 39.650  -28.806 16.811  1.00 31.84  ? 273 MET B CE  1 
ATOM   4315  N  N   . LEU B 1 274 ? 38.116  -35.029 20.080  1.00 28.10  ? 274 LEU B N   1 
ATOM   4316  C  CA  . LEU B 1 274 ? 37.534  -35.887 21.100  1.00 29.73  ? 274 LEU B CA  1 
ATOM   4317  C  C   . LEU B 1 274 ? 38.427  -37.088 21.469  1.00 29.04  ? 274 LEU B C   1 
ATOM   4318  O  O   . LEU B 1 274 ? 38.528  -37.454 22.630  1.00 28.19  ? 274 LEU B O   1 
ATOM   4319  C  CB  . LEU B 1 274 ? 36.160  -36.359 20.643  1.00 31.33  ? 274 LEU B CB  1 
ATOM   4320  C  CG  . LEU B 1 274 ? 35.006  -35.359 20.777  1.00 30.83  ? 274 LEU B CG  1 
ATOM   4321  C  CD1 . LEU B 1 274 ? 33.726  -35.946 20.133  1.00 31.22  ? 274 LEU B CD1 1 
ATOM   4322  C  CD2 . LEU B 1 274 ? 34.765  -35.033 22.240  1.00 31.54  ? 274 LEU B CD2 1 
ATOM   4323  N  N   . GLU B 1 275 ? 39.025  -37.750 20.482  1.00 31.63  ? 275 GLU B N   1 
ATOM   4324  C  CA  . GLU B 1 275 ? 39.894  -38.888 20.751  1.00 32.75  ? 275 GLU B CA  1 
ATOM   4325  C  C   . GLU B 1 275 ? 41.122  -38.452 21.552  1.00 29.42  ? 275 GLU B C   1 
ATOM   4326  O  O   . GLU B 1 275 ? 41.522  -39.106 22.517  1.00 28.56  ? 275 GLU B O   1 
ATOM   4327  C  CB  . GLU B 1 275 ? 40.511  -39.517 19.527  1.00 35.83  ? 275 GLU B CB  1 
ATOM   4328  C  CG  . GLU B 1 275 ? 39.576  -40.423 18.740  1.00 43.58  ? 275 GLU B CG  1 
ATOM   4329  C  CD  . GLU B 1 275 ? 40.419  -40.982 17.553  1.00 55.18  ? 275 GLU B CD  1 
ATOM   4330  O  OE1 . GLU B 1 275 ? 41.713  -41.059 17.536  1.00 63.44  ? 275 GLU B OE1 1 
ATOM   4331  O  OE2 . GLU B 1 275 ? 39.767  -41.310 16.556  1.00 43.98  ? 275 GLU B OE2 1 
ATOM   4332  N  N   . ARG B 1 276 ? 41.679  -37.308 21.209  1.00 24.86  ? 276 ARG B N   1 
ATOM   4333  C  CA  . ARG B 1 276 ? 42.784  -36.780 21.976  1.00 30.75  ? 276 ARG B CA  1 
ATOM   4334  C  C   . ARG B 1 276 ? 42.389  -36.494 23.427  1.00 33.96  ? 276 ARG B C   1 
ATOM   4335  O  O   . ARG B 1 276 ? 43.180  -36.719 24.329  1.00 33.87  ? 276 ARG B O   1 
ATOM   4336  C  CB  . ARG B 1 276 ? 43.382  -35.539 21.312  1.00 33.77  ? 276 ARG B CB  1 
ATOM   4337  C  CG  . ARG B 1 276 ? 44.140  -35.994 20.076  1.00 37.16  ? 276 ARG B CG  1 
ATOM   4338  C  CD  . ARG B 1 276 ? 44.263  -34.951 18.986  1.00 45.12  ? 276 ARG B CD  1 
ATOM   4339  N  NE  . ARG B 1 276 ? 44.973  -33.756 19.463  1.00 55.32  ? 276 ARG B NE  1 
ATOM   4340  C  CZ  . ARG B 1 276 ? 46.283  -33.662 19.638  1.00 60.61  ? 276 ARG B CZ  1 
ATOM   4341  N  NH1 . ARG B 1 276 ? 47.089  -34.634 19.283  1.00 76.74  ? 276 ARG B NH1 1 
ATOM   4342  N  NH2 . ARG B 1 276 ? 46.800  -32.612 20.204  1.00 50.73  ? 276 ARG B NH2 1 
ATOM   4343  N  N   . MET B 1 277 ? 41.186  -35.953 23.633  1.00 34.26  ? 277 MET B N   1 
ATOM   4344  C  CA  . MET B 1 277 ? 40.744  -35.589 24.966  1.00 33.88  ? 277 MET B CA  1 
ATOM   4345  C  C   . MET B 1 277 ? 40.487  -36.852 25.788  1.00 28.52  ? 277 MET B C   1 
ATOM   4346  O  O   . MET B 1 277 ? 40.874  -36.933 26.936  1.00 23.71  ? 277 MET B O   1 
ATOM   4347  C  CB  . MET B 1 277 ? 39.461  -34.745 24.898  1.00 34.23  ? 277 MET B CB  1 
ATOM   4348  C  CG  . MET B 1 277 ? 39.668  -33.311 24.368  1.00 31.59  ? 277 MET B CG  1 
ATOM   4349  S  SD  . MET B 1 277 ? 38.045  -32.487 24.329  1.00 31.11  ? 277 MET B SD  1 
ATOM   4350  C  CE  . MET B 1 277 ? 37.482  -32.469 26.035  1.00 29.86  ? 277 MET B CE  1 
ATOM   4351  N  N   . PHE B 1 278 ? 39.801  -37.829 25.200  1.00 28.35  ? 278 PHE B N   1 
ATOM   4352  C  CA  . PHE B 1 278 ? 39.334  -38.955 25.975  1.00 29.34  ? 278 PHE B CA  1 
ATOM   4353  C  C   . PHE B 1 278 ? 40.334  -40.110 26.015  1.00 39.66  ? 278 PHE B C   1 
ATOM   4354  O  O   . PHE B 1 278 ? 40.362  -40.861 27.022  1.00 37.18  ? 278 PHE B O   1 
ATOM   4355  C  CB  . PHE B 1 278 ? 38.016  -39.449 25.410  1.00 27.75  ? 278 PHE B CB  1 
ATOM   4356  C  CG  . PHE B 1 278 ? 36.864  -38.605 25.911  1.00 27.64  ? 278 PHE B CG  1 
ATOM   4357  C  CD1 . PHE B 1 278 ? 36.503  -37.438 25.250  1.00 27.71  ? 278 PHE B CD1 1 
ATOM   4358  C  CD2 . PHE B 1 278 ? 36.188  -38.943 27.059  1.00 28.23  ? 278 PHE B CD2 1 
ATOM   4359  C  CE1 . PHE B 1 278 ? 35.501  -36.626 25.733  1.00 24.40  ? 278 PHE B CE1 1 
ATOM   4360  C  CE2 . PHE B 1 278 ? 35.161  -38.139 27.505  1.00 26.68  ? 278 PHE B CE2 1 
ATOM   4361  C  CZ  . PHE B 1 278 ? 34.825  -36.983 26.854  1.00 25.05  ? 278 PHE B CZ  1 
ATOM   4362  N  N   . LEU B 1 279 ? 41.066  -40.316 24.904  1.00 36.87  ? 279 LEU B N   1 
ATOM   4363  C  CA  . LEU B 1 279 ? 41.911  -41.498 24.808  1.00 37.70  ? 279 LEU B CA  1 
ATOM   4364  C  C   . LEU B 1 279 ? 43.353  -41.128 25.049  1.00 39.27  ? 279 LEU B C   1 
ATOM   4365  O  O   . LEU B 1 279 ? 44.111  -41.993 25.413  1.00 49.31  ? 279 LEU B O   1 
ATOM   4366  C  CB  . LEU B 1 279 ? 41.799  -42.154 23.448  1.00 34.94  ? 279 LEU B CB  1 
ATOM   4367  C  CG  . LEU B 1 279 ? 40.398  -42.611 23.044  1.00 39.03  ? 279 LEU B CG  1 
ATOM   4368  C  CD1 . LEU B 1 279 ? 40.514  -43.308 21.697  1.00 38.96  ? 279 LEU B CD1 1 
ATOM   4369  C  CD2 . LEU B 1 279 ? 39.749  -43.522 24.055  1.00 40.54  ? 279 LEU B CD2 1 
ATOM   4370  N  N   . GLY B 1 280 ? 43.732  -39.875 24.865  1.00 36.92  ? 280 GLY B N   1 
ATOM   4371  C  CA  . GLY B 1 280 ? 45.109  -39.528 25.170  1.00 44.91  ? 280 GLY B CA  1 
ATOM   4372  C  C   . GLY B 1 280 ? 46.005  -39.451 23.942  1.00 43.97  ? 280 GLY B C   1 
ATOM   4373  O  O   . GLY B 1 280 ? 45.570  -39.657 22.830  1.00 46.24  ? 280 GLY B O   1 
ATOM   4374  N  N   . THR B 1 281 ? 47.238  -39.000 24.182  1.00 44.91  ? 281 THR B N   1 
ATOM   4375  C  CA  . THR B 1 281 ? 48.333  -38.994 23.226  1.00 46.17  ? 281 THR B CA  1 
ATOM   4376  C  C   . THR B 1 281 ? 49.552  -39.675 23.865  1.00 45.80  ? 281 THR B C   1 
ATOM   4377  O  O   . THR B 1 281 ? 49.504  -40.201 24.983  1.00 40.03  ? 281 THR B O   1 
ATOM   4378  C  CB  . THR B 1 281 ? 48.628  -37.544 22.829  1.00 44.85  ? 281 THR B CB  1 
ATOM   4379  O  OG1 . THR B 1 281 ? 49.103  -36.809 23.959  1.00 45.74  ? 281 THR B OG1 1 
ATOM   4380  C  CG2 . THR B 1 281 ? 47.393  -36.885 22.260  1.00 41.98  ? 281 THR B CG2 1 
ATOM   4381  N  N   . ALA B 1 282 ? 50.683  -39.649 23.171  1.00 49.46  ? 282 ALA B N   1 
ATOM   4382  C  CA  . ALA B 1 282 ? 51.905  -40.173 23.767  1.00 51.45  ? 282 ALA B CA  1 
ATOM   4383  C  C   . ALA B 1 282 ? 52.241  -39.361 25.010  1.00 57.05  ? 282 ALA B C   1 
ATOM   4384  O  O   . ALA B 1 282 ? 52.632  -39.904 26.023  1.00 53.94  ? 282 ALA B O   1 
ATOM   4385  C  CB  . ALA B 1 282 ? 53.045  -40.089 22.778  1.00 57.27  ? 282 ALA B CB  1 
ATOM   4386  N  N   . SER B 1 283 ? 52.058  -38.038 24.949  1.00 61.53  ? 283 SER B N   1 
ATOM   4387  C  CA  . SER B 1 283 ? 52.434  -37.163 26.050  1.00 61.57  ? 283 SER B CA  1 
ATOM   4388  C  C   . SER B 1 283 ? 51.398  -37.081 27.174  1.00 63.55  ? 283 SER B C   1 
ATOM   4389  O  O   . SER B 1 283 ? 51.712  -36.530 28.209  1.00 63.37  ? 283 SER B O   1 
ATOM   4390  C  CB  . SER B 1 283 ? 52.580  -35.756 25.592  1.00 61.07  ? 283 SER B CB  1 
ATOM   4391  O  OG  . SER B 1 283 ? 53.174  -35.615 24.319  1.00 61.65  ? 283 SER B OG  1 
ATOM   4392  N  N   . ALA B 1 284 ? 50.135  -37.447 26.943  1.00 63.50  ? 284 ALA B N   1 
ATOM   4393  C  CA  . ALA B 1 284 ? 49.085  -37.010 27.841  1.00 51.13  ? 284 ALA B CA  1 
ATOM   4394  C  C   . ALA B 1 284 ? 48.095  -38.145 28.032  1.00 43.32  ? 284 ALA B C   1 
ATOM   4395  O  O   . ALA B 1 284 ? 47.478  -38.641 27.086  1.00 44.70  ? 284 ALA B O   1 
ATOM   4396  C  CB  . ALA B 1 284 ? 48.410  -35.791 27.240  1.00 57.07  ? 284 ALA B CB  1 
ATOM   4397  N  N   . PRO B 1 285 ? 47.845  -38.570 29.275  1.00 29.03  ? 285 PRO B N   1 
ATOM   4398  C  CA  . PRO B 1 285 ? 46.885  -39.648 29.437  1.00 30.30  ? 285 PRO B CA  1 
ATOM   4399  C  C   . PRO B 1 285 ? 45.489  -39.277 28.930  1.00 32.44  ? 285 PRO B C   1 
ATOM   4400  O  O   . PRO B 1 285 ? 44.792  -40.175 28.479  1.00 31.17  ? 285 PRO B O   1 
ATOM   4401  C  CB  . PRO B 1 285 ? 46.945  -39.975 30.922  1.00 25.60  ? 285 PRO B CB  1 
ATOM   4402  C  CG  . PRO B 1 285 ? 47.659  -38.796 31.516  1.00 29.38  ? 285 PRO B CG  1 
ATOM   4403  C  CD  . PRO B 1 285 ? 48.503  -38.097 30.499  1.00 27.97  ? 285 PRO B CD  1 
ATOM   4404  N  N   . HIS B 1 286 ? 45.077  -37.999 29.119  1.00 31.85  ? 286 HIS B N   1 
ATOM   4405  C  CA  . HIS B 1 286 ? 43.754  -37.493 28.774  1.00 29.93  ? 286 HIS B CA  1 
ATOM   4406  C  C   . HIS B 1 286 ? 43.707  -36.003 29.113  1.00 31.96  ? 286 HIS B C   1 
ATOM   4407  O  O   . HIS B 1 286 ? 44.640  -35.494 29.742  1.00 28.47  ? 286 HIS B O   1 
ATOM   4408  C  CB  . HIS B 1 286 ? 42.625  -38.222 29.494  1.00 29.80  ? 286 HIS B CB  1 
ATOM   4409  C  CG  . HIS B 1 286 ? 42.741  -38.209 30.976  1.00 41.81  ? 286 HIS B CG  1 
ATOM   4410  N  ND1 . HIS B 1 286 ? 43.138  -39.333 31.690  1.00 39.59  ? 286 HIS B ND1 1 
ATOM   4411  C  CD2 . HIS B 1 286 ? 42.453  -37.203 31.882  1.00 41.01  ? 286 HIS B CD2 1 
ATOM   4412  C  CE1 . HIS B 1 286 ? 43.082  -39.003 32.987  1.00 39.84  ? 286 HIS B CE1 1 
ATOM   4413  N  NE2 . HIS B 1 286 ? 42.655  -37.716 33.136  1.00 35.08  ? 286 HIS B NE2 1 
ATOM   4414  N  N   . ASP B 1 287 ? 42.624  -35.328 28.669  1.00 33.64  ? 287 ASP B N   1 
ATOM   4415  C  CA  . ASP B 1 287 ? 42.407  -33.909 28.921  1.00 31.24  ? 287 ASP B CA  1 
ATOM   4416  C  C   . ASP B 1 287 ? 42.029  -33.722 30.381  1.00 27.00  ? 287 ASP B C   1 
ATOM   4417  O  O   . ASP B 1 287 ? 41.075  -34.314 30.873  1.00 23.42  ? 287 ASP B O   1 
ATOM   4418  C  CB  . ASP B 1 287 ? 41.323  -33.391 27.985  1.00 31.95  ? 287 ASP B CB  1 
ATOM   4419  C  CG  . ASP B 1 287 ? 41.132  -31.883 27.962  1.00 29.17  ? 287 ASP B CG  1 
ATOM   4420  O  OD1 . ASP B 1 287 ? 41.449  -31.236 28.952  1.00 27.73  ? 287 ASP B OD1 1 
ATOM   4421  O  OD2 . ASP B 1 287 ? 40.686  -31.376 26.928  1.00 33.24  ? 287 ASP B OD2 1 
ATOM   4422  N  N   . ARG B 1 288 ? 42.836  -32.931 31.089  1.00 27.78  ? 288 ARG B N   1 
ATOM   4423  C  CA  . ARG B 1 288 ? 42.589  -32.649 32.486  1.00 31.49  ? 288 ARG B CA  1 
ATOM   4424  C  C   . ARG B 1 288 ? 41.204  -32.061 32.767  1.00 31.39  ? 288 ARG B C   1 
ATOM   4425  O  O   . ARG B 1 288 ? 40.693  -32.168 33.874  1.00 27.92  ? 288 ARG B O   1 
ATOM   4426  C  CB  . ARG B 1 288 ? 43.717  -31.728 32.967  1.00 35.89  ? 288 ARG B CB  1 
ATOM   4427  C  CG  . ARG B 1 288 ? 45.017  -32.475 33.261  1.00 35.50  ? 288 ARG B CG  1 
ATOM   4428  C  CD  . ARG B 1 288 ? 44.928  -33.165 34.604  1.00 34.78  ? 288 ARG B CD  1 
ATOM   4429  N  NE  . ARG B 1 288 ? 44.978  -32.221 35.739  1.00 37.94  ? 288 ARG B NE  1 
ATOM   4430  C  CZ  . ARG B 1 288 ? 44.370  -32.326 36.921  1.00 30.23  ? 288 ARG B CZ  1 
ATOM   4431  N  NH1 . ARG B 1 288 ? 43.492  -33.291 37.160  1.00 29.17  ? 288 ARG B NH1 1 
ATOM   4432  N  NH2 . ARG B 1 288 ? 44.664  -31.463 37.882  1.00 27.88  ? 288 ARG B NH2 1 
ATOM   4433  N  N   . ILE B 1 289 ? 40.569  -31.446 31.787  1.00 27.97  ? 289 ILE B N   1 
ATOM   4434  C  CA  . ILE B 1 289 ? 39.261  -30.890 32.067  1.00 30.56  ? 289 ILE B CA  1 
ATOM   4435  C  C   . ILE B 1 289 ? 38.253  -32.000 32.369  1.00 26.62  ? 289 ILE B C   1 
ATOM   4436  O  O   . ILE B 1 289 ? 37.260  -31.757 33.042  1.00 25.57  ? 289 ILE B O   1 
ATOM   4437  C  CB  . ILE B 1 289 ? 38.806  -29.994 30.906  1.00 31.52  ? 289 ILE B CB  1 
ATOM   4438  C  CG1 . ILE B 1 289 ? 37.895  -28.899 31.404  1.00 29.90  ? 289 ILE B CG1 1 
ATOM   4439  C  CG2 . ILE B 1 289 ? 38.232  -30.825 29.755  1.00 29.71  ? 289 ILE B CG2 1 
ATOM   4440  C  CD1 . ILE B 1 289 ? 37.589  -27.917 30.291  1.00 35.40  ? 289 ILE B CD1 1 
ATOM   4441  N  N   . LEU B 1 290 ? 38.482  -33.212 31.848  1.00 23.80  ? 290 LEU B N   1 
ATOM   4442  C  CA  . LEU B 1 290 ? 37.586  -34.337 32.108  1.00 24.54  ? 290 LEU B CA  1 
ATOM   4443  C  C   . LEU B 1 290 ? 37.698  -34.848 33.551  1.00 23.04  ? 290 LEU B C   1 
ATOM   4444  O  O   . LEU B 1 290 ? 36.819  -35.531 34.055  1.00 27.38  ? 290 LEU B O   1 
ATOM   4445  C  CB  . LEU B 1 290 ? 37.869  -35.431 31.095  1.00 24.15  ? 290 LEU B CB  1 
ATOM   4446  C  CG  . LEU B 1 290 ? 37.615  -35.071 29.643  1.00 26.86  ? 290 LEU B CG  1 
ATOM   4447  C  CD1 . LEU B 1 290 ? 38.012  -36.236 28.760  1.00 28.52  ? 290 LEU B CD1 1 
ATOM   4448  C  CD2 . LEU B 1 290 ? 36.195  -34.638 29.394  1.00 28.50  ? 290 LEU B CD2 1 
ATOM   4449  N  N   . ASP B 1 291 ? 38.725  -34.424 34.283  1.00 25.34  ? 291 ASP B N   1 
ATOM   4450  C  CA  . ASP B 1 291 ? 38.791  -34.773 35.696  1.00 27.37  ? 291 ASP B CA  1 
ATOM   4451  C  C   . ASP B 1 291 ? 37.809  -33.923 36.480  1.00 26.76  ? 291 ASP B C   1 
ATOM   4452  O  O   . ASP B 1 291 ? 37.644  -34.146 37.654  1.00 27.73  ? 291 ASP B O   1 
ATOM   4453  C  CB  . ASP B 1 291 ? 40.193  -34.697 36.275  1.00 26.89  ? 291 ASP B CB  1 
ATOM   4454  C  CG  . ASP B 1 291 ? 41.199  -35.687 35.668  1.00 30.04  ? 291 ASP B CG  1 
ATOM   4455  O  OD1 . ASP B 1 291 ? 40.814  -36.791 35.230  1.00 29.78  ? 291 ASP B OD1 1 
ATOM   4456  O  OD2 . ASP B 1 291 ? 42.372  -35.326 35.593  1.00 28.43  ? 291 ASP B OD2 1 
ATOM   4457  N  N   . PHE B 1 292 ? 37.149  -32.942 35.850  1.00 29.68  ? 292 PHE B N   1 
ATOM   4458  C  CA  . PHE B 1 292 ? 36.135  -32.119 36.503  1.00 24.43  ? 292 PHE B CA  1 
ATOM   4459  C  C   . PHE B 1 292 ? 34.841  -32.072 35.698  1.00 23.78  ? 292 PHE B C   1 
ATOM   4460  O  O   . PHE B 1 292 ? 33.958  -31.294 36.010  1.00 25.03  ? 292 PHE B O   1 
ATOM   4461  C  CB  . PHE B 1 292 ? 36.682  -30.698 36.652  1.00 22.68  ? 292 PHE B CB  1 
ATOM   4462  C  CG  . PHE B 1 292 ? 37.983  -30.720 37.404  1.00 25.48  ? 292 PHE B CG  1 
ATOM   4463  C  CD1 . PHE B 1 292 ? 37.999  -30.764 38.783  1.00 22.79  ? 292 PHE B CD1 1 
ATOM   4464  C  CD2 . PHE B 1 292 ? 39.200  -30.776 36.723  1.00 28.85  ? 292 PHE B CD2 1 
ATOM   4465  C  CE1 . PHE B 1 292 ? 39.199  -30.747 39.470  1.00 23.79  ? 292 PHE B CE1 1 
ATOM   4466  C  CE2 . PHE B 1 292 ? 40.391  -30.807 37.435  1.00 28.26  ? 292 PHE B CE2 1 
ATOM   4467  C  CZ  . PHE B 1 292 ? 40.386  -30.807 38.798  1.00 23.46  ? 292 PHE B CZ  1 
ATOM   4468  N  N   . SER B 1 293 ? 34.742  -32.853 34.634  1.00 24.46  ? 293 SER B N   1 
ATOM   4469  C  CA  . SER B 1 293 ? 33.628  -32.728 33.718  1.00 26.03  ? 293 SER B CA  1 
ATOM   4470  C  C   . SER B 1 293 ? 33.253  -34.131 33.234  1.00 30.60  ? 293 SER B C   1 
ATOM   4471  O  O   . SER B 1 293 ? 34.150  -34.849 32.800  1.00 32.79  ? 293 SER B O   1 
ATOM   4472  C  CB  . SER B 1 293 ? 33.968  -31.827 32.528  1.00 25.23  ? 293 SER B CB  1 
ATOM   4473  O  OG  . SER B 1 293 ? 34.705  -30.675 32.910  1.00 26.11  ? 293 SER B OG  1 
ATOM   4474  N  N   . THR B 1 294 ? 31.966  -34.502 33.345  1.00 27.11  ? 294 THR B N   1 
ATOM   4475  C  CA  . THR B 1 294 ? 31.453  -35.777 32.875  1.00 28.59  ? 294 THR B CA  1 
ATOM   4476  C  C   . THR B 1 294 ? 30.442  -35.518 31.758  1.00 27.55  ? 294 THR B C   1 
ATOM   4477  O  O   . THR B 1 294 ? 29.496  -34.761 31.946  1.00 23.07  ? 294 THR B O   1 
ATOM   4478  C  CB  . THR B 1 294 ? 30.786  -36.491 34.078  1.00 29.49  ? 294 THR B CB  1 
ATOM   4479  O  OG1 . THR B 1 294 ? 31.718  -36.667 35.141  1.00 27.07  ? 294 THR B OG1 1 
ATOM   4480  C  CG2 . THR B 1 294 ? 30.157  -37.819 33.726  1.00 27.00  ? 294 THR B CG2 1 
ATOM   4481  N  N   . ALA B 1 295 ? 30.611  -36.224 30.637  1.00 26.14  ? 295 ALA B N   1 
ATOM   4482  C  CA  . ALA B 1 295 ? 29.704  -36.152 29.507  1.00 26.56  ? 295 ALA B CA  1 
ATOM   4483  C  C   . ALA B 1 295 ? 28.541  -37.063 29.783  1.00 28.03  ? 295 ALA B C   1 
ATOM   4484  O  O   . ALA B 1 295 ? 28.771  -38.220 30.032  1.00 32.10  ? 295 ALA B O   1 
ATOM   4485  C  CB  . ALA B 1 295 ? 30.403  -36.599 28.256  1.00 28.15  ? 295 ALA B CB  1 
ATOM   4486  N  N   . VAL B 1 296 ? 27.308  -36.581 29.704  1.00 27.85  ? 296 VAL B N   1 
ATOM   4487  C  CA  . VAL B 1 296 ? 26.158  -37.455 29.926  1.00 28.57  ? 296 VAL B CA  1 
ATOM   4488  C  C   . VAL B 1 296 ? 25.261  -37.584 28.693  1.00 28.98  ? 296 VAL B C   1 
ATOM   4489  O  O   . VAL B 1 296 ? 24.383  -38.424 28.706  1.00 26.04  ? 296 VAL B O   1 
ATOM   4490  C  CB  . VAL B 1 296 ? 25.367  -37.006 31.162  1.00 29.95  ? 296 VAL B CB  1 
ATOM   4491  C  CG1 . VAL B 1 296 ? 26.289  -36.986 32.355  1.00 29.26  ? 296 VAL B CG1 1 
ATOM   4492  C  CG2 . VAL B 1 296 ? 24.664  -35.671 30.950  1.00 28.62  ? 296 VAL B CG2 1 
ATOM   4493  N  N   . THR B 1 297 ? 25.555  -36.857 27.592  1.00 29.99  ? 297 THR B N   1 
ATOM   4494  C  CA  . THR B 1 297 ? 24.952  -37.119 26.292  1.00 26.47  ? 297 THR B CA  1 
ATOM   4495  C  C   . THR B 1 297 ? 26.056  -37.031 25.268  1.00 26.89  ? 297 THR B C   1 
ATOM   4496  O  O   . THR B 1 297 ? 27.127  -36.485 25.514  1.00 27.56  ? 297 THR B O   1 
ATOM   4497  C  CB  . THR B 1 297 ? 23.818  -36.161 25.912  1.00 24.66  ? 297 THR B CB  1 
ATOM   4498  O  OG1 . THR B 1 297 ? 24.338  -34.840 25.709  1.00 25.39  ? 297 THR B OG1 1 
ATOM   4499  C  CG2 . THR B 1 297 ? 22.737  -36.171 26.965  1.00 23.63  ? 297 THR B CG2 1 
ATOM   4500  N  N   . GLY B 1 298 ? 25.742  -37.555 24.090  1.00 27.70  ? 298 GLY B N   1 
ATOM   4501  C  CA  . GLY B 1 298 ? 26.628  -37.412 22.958  1.00 26.64  ? 298 GLY B CA  1 
ATOM   4502  C  C   . GLY B 1 298 ? 25.827  -37.707 21.699  1.00 28.39  ? 298 GLY B C   1 
ATOM   4503  O  O   . GLY B 1 298 ? 25.244  -38.767 21.588  1.00 27.66  ? 298 GLY B O   1 
ATOM   4504  N  N   . SER B 1 299 ? 25.777  -36.757 20.759  1.00 31.23  ? 299 SER B N   1 
ATOM   4505  C  CA  . SER B 1 299 ? 25.065  -36.981 19.505  1.00 25.39  ? 299 SER B CA  1 
ATOM   4506  C  C   . SER B 1 299 ? 25.726  -36.179 18.421  1.00 23.33  ? 299 SER B C   1 
ATOM   4507  O  O   . SER B 1 299 ? 26.380  -35.177 18.708  1.00 22.53  ? 299 SER B O   1 
ATOM   4508  C  CB  . SER B 1 299 ? 23.612  -36.637 19.588  1.00 24.99  ? 299 SER B CB  1 
ATOM   4509  O  OG  . SER B 1 299 ? 22.970  -37.405 20.599  1.00 27.06  ? 299 SER B OG  1 
ATOM   4510  N  N   . LEU B 1 300 ? 25.489  -36.639 17.178  1.00 27.28  ? 300 LEU B N   1 
ATOM   4511  C  CA  . LEU B 1 300 ? 26.021  -36.003 15.979  1.00 30.82  ? 300 LEU B CA  1 
ATOM   4512  C  C   . LEU B 1 300 ? 24.874  -35.744 15.022  1.00 26.85  ? 300 LEU B C   1 
ATOM   4513  O  O   . LEU B 1 300 ? 24.036  -36.606 14.855  1.00 27.77  ? 300 LEU B O   1 
ATOM   4514  C  CB  . LEU B 1 300 ? 27.087  -36.908 15.371  1.00 33.31  ? 300 LEU B CB  1 
ATOM   4515  C  CG  . LEU B 1 300 ? 27.981  -36.321 14.288  1.00 38.05  ? 300 LEU B CG  1 
ATOM   4516  C  CD1 . LEU B 1 300 ? 29.192  -37.179 13.997  1.00 47.80  ? 300 LEU B CD1 1 
ATOM   4517  C  CD2 . LEU B 1 300 ? 27.266  -36.273 13.023  1.00 46.13  ? 300 LEU B CD2 1 
ATOM   4518  N  N   . PHE B 1 301 ? 24.877  -34.560 14.406  1.00 27.05  ? 301 PHE B N   1 
ATOM   4519  C  CA  . PHE B 1 301 ? 23.836  -34.139 13.473  1.00 28.35  ? 301 PHE B CA  1 
ATOM   4520  C  C   . PHE B 1 301 ? 24.440  -33.463 12.258  1.00 26.53  ? 301 PHE B C   1 
ATOM   4521  O  O   . PHE B 1 301 ? 25.488  -32.861 12.342  1.00 27.19  ? 301 PHE B O   1 
ATOM   4522  C  CB  . PHE B 1 301 ? 22.901  -33.089 14.087  1.00 28.04  ? 301 PHE B CB  1 
ATOM   4523  C  CG  . PHE B 1 301 ? 22.254  -33.633 15.323  1.00 23.59  ? 301 PHE B CG  1 
ATOM   4524  C  CD1 . PHE B 1 301 ? 21.096  -34.355 15.248  1.00 26.51  ? 301 PHE B CD1 1 
ATOM   4525  C  CD2 . PHE B 1 301 ? 22.834  -33.431 16.535  1.00 24.39  ? 301 PHE B CD2 1 
ATOM   4526  C  CE1 . PHE B 1 301 ? 20.532  -34.889 16.412  1.00 32.33  ? 301 PHE B CE1 1 
ATOM   4527  C  CE2 . PHE B 1 301 ? 22.254  -33.920 17.667  1.00 27.34  ? 301 PHE B CE2 1 
ATOM   4528  C  CZ  . PHE B 1 301 ? 21.115  -34.679 17.616  1.00 27.58  ? 301 PHE B CZ  1 
ATOM   4529  N  N   . PHE B 1 302 ? 23.736  -33.549 11.128  1.00 29.77  ? 302 PHE B N   1 
ATOM   4530  C  CA  . PHE B 1 302 ? 24.037  -32.750 9.940   1.00 28.74  ? 302 PHE B CA  1 
ATOM   4531  C  C   . PHE B 1 302 ? 23.002  -31.626 9.869   1.00 26.64  ? 302 PHE B C   1 
ATOM   4532  O  O   . PHE B 1 302 ? 21.776  -31.861 9.971   1.00 30.55  ? 302 PHE B O   1 
ATOM   4533  C  CB  . PHE B 1 302 ? 23.983  -33.657 8.690   1.00 28.00  ? 302 PHE B CB  1 
ATOM   4534  C  CG  . PHE B 1 302 ? 24.238  -32.867 7.425   1.00 25.87  ? 302 PHE B CG  1 
ATOM   4535  C  CD1 . PHE B 1 302 ? 25.502  -32.371 7.162   1.00 30.67  ? 302 PHE B CD1 1 
ATOM   4536  C  CD2 . PHE B 1 302 ? 23.215  -32.565 6.566   1.00 26.73  ? 302 PHE B CD2 1 
ATOM   4537  C  CE1 . PHE B 1 302 ? 25.764  -31.631 6.019   1.00 35.02  ? 302 PHE B CE1 1 
ATOM   4538  C  CE2 . PHE B 1 302 ? 23.486  -31.886 5.382   1.00 33.93  ? 302 PHE B CE2 1 
ATOM   4539  C  CZ  . PHE B 1 302 ? 24.759  -31.372 5.133   1.00 35.18  ? 302 PHE B CZ  1 
ATOM   4540  N  N   . THR B 1 303 ? 23.511  -30.414 9.726   1.00 25.99  ? 303 THR B N   1 
ATOM   4541  C  CA  . THR B 1 303 ? 22.656  -29.242 9.620   1.00 28.10  ? 303 THR B CA  1 
ATOM   4542  C  C   . THR B 1 303 ? 22.672  -28.816 8.150   1.00 30.18  ? 303 THR B C   1 
ATOM   4543  O  O   . THR B 1 303 ? 23.634  -28.205 7.682   1.00 33.61  ? 303 THR B O   1 
ATOM   4544  C  CB  . THR B 1 303 ? 23.104  -28.089 10.536  1.00 27.74  ? 303 THR B CB  1 
ATOM   4545  O  OG1 . THR B 1 303 ? 24.410  -27.597 10.273  1.00 23.47  ? 303 THR B OG1 1 
ATOM   4546  C  CG2 . THR B 1 303 ? 23.143  -28.506 11.992  1.00 32.50  ? 303 THR B CG2 1 
ATOM   4547  N  N   . PRO B 1 304 ? 21.621  -29.124 7.370   1.00 27.71  ? 304 PRO B N   1 
ATOM   4548  C  CA  . PRO B 1 304 ? 21.630  -28.812 5.944   1.00 28.99  ? 304 PRO B CA  1 
ATOM   4549  C  C   . PRO B 1 304 ? 21.625  -27.325 5.655   1.00 34.18  ? 304 PRO B C   1 
ATOM   4550  O  O   . PRO B 1 304 ? 21.297  -26.488 6.534   1.00 28.19  ? 304 PRO B O   1 
ATOM   4551  C  CB  . PRO B 1 304 ? 20.368  -29.430 5.404   1.00 29.49  ? 304 PRO B CB  1 
ATOM   4552  C  CG  . PRO B 1 304 ? 19.731  -30.160 6.562   1.00 29.55  ? 304 PRO B CG  1 
ATOM   4553  C  CD  . PRO B 1 304 ? 20.397  -29.778 7.834   1.00 26.03  ? 304 PRO B CD  1 
ATOM   4554  N  N   . ALA B 1 305 ? 21.942  -27.027 4.373   1.00 33.71  ? 305 ALA B N   1 
ATOM   4555  C  CA  . ALA B 1 305 ? 21.696  -25.677 3.877   1.00 36.39  ? 305 ALA B CA  1 
ATOM   4556  C  C   . ALA B 1 305 ? 20.197  -25.365 4.014   1.00 35.62  ? 305 ALA B C   1 
ATOM   4557  O  O   . ALA B 1 305 ? 19.362  -26.290 3.944   1.00 30.70  ? 305 ALA B O   1 
ATOM   4558  C  CB  . ALA B 1 305 ? 22.208  -25.489 2.472   1.00 34.39  ? 305 ALA B CB  1 
ATOM   4559  N  N   . ALA B 1 306 ? 19.875  -24.083 4.302   1.00 33.03  ? 306 ALA B N   1 
ATOM   4560  C  CA  . ALA B 1 306 ? 18.475  -23.711 4.533   1.00 35.19  ? 306 ALA B CA  1 
ATOM   4561  C  C   . ALA B 1 306 ? 17.607  -24.026 3.331   1.00 38.98  ? 306 ALA B C   1 
ATOM   4562  O  O   . ALA B 1 306 ? 16.490  -24.426 3.587   1.00 36.74  ? 306 ALA B O   1 
ATOM   4563  C  CB  . ALA B 1 306 ? 18.317  -22.289 4.852   1.00 35.92  ? 306 ALA B CB  1 
ATOM   4564  N  N   . ASP B 1 307 ? 18.129  -23.871 2.081   1.00 41.74  ? 307 ASP B N   1 
ATOM   4565  C  CA  . ASP B 1 307 ? 17.389  -24.182 0.850   1.00 40.98  ? 307 ASP B CA  1 
ATOM   4566  C  C   . ASP B 1 307 ? 16.941  -25.640 0.824   1.00 40.33  ? 307 ASP B C   1 
ATOM   4567  O  O   . ASP B 1 307 ? 15.834  -25.954 0.373   1.00 39.47  ? 307 ASP B O   1 
ATOM   4568  C  CB  . ASP B 1 307 ? 18.227  -24.185 -0.407  1.00 47.50  ? 307 ASP B CB  1 
ATOM   4569  C  CG  . ASP B 1 307 ? 19.157  -23.014 -0.487  1.00 67.49  ? 307 ASP B CG  1 
ATOM   4570  O  OD1 . ASP B 1 307 ? 18.611  -21.891 -0.466  1.00 104.94 ? 307 ASP B OD1 1 
ATOM   4571  O  OD2 . ASP B 1 307 ? 20.388  -23.254 -0.504  1.00 86.43  ? 307 ASP B OD2 1 
ATOM   4572  N  N   . PHE B 1 308 ? 17.797  -26.548 1.323   1.00 43.01  ? 308 PHE B N   1 
ATOM   4573  C  CA  . PHE B 1 308 ? 17.438  -27.964 1.370   1.00 40.09  ? 308 PHE B CA  1 
ATOM   4574  C  C   . PHE B 1 308 ? 16.131  -28.134 2.166   1.00 37.24  ? 308 PHE B C   1 
ATOM   4575  O  O   . PHE B 1 308 ? 15.265  -28.868 1.740   1.00 41.78  ? 308 PHE B O   1 
ATOM   4576  C  CB  . PHE B 1 308 ? 18.654  -28.781 1.827   1.00 32.42  ? 308 PHE B CB  1 
ATOM   4577  C  CG  . PHE B 1 308 ? 18.322  -30.254 2.017   1.00 36.65  ? 308 PHE B CG  1 
ATOM   4578  C  CD1 . PHE B 1 308 ? 17.639  -30.716 3.152   1.00 36.97  ? 308 PHE B CD1 1 
ATOM   4579  C  CD2 . PHE B 1 308 ? 18.714  -31.183 1.071   1.00 36.77  ? 308 PHE B CD2 1 
ATOM   4580  C  CE1 . PHE B 1 308 ? 17.342  -32.047 3.329   1.00 38.52  ? 308 PHE B CE1 1 
ATOM   4581  C  CE2 . PHE B 1 308 ? 18.386  -32.535 1.232   1.00 37.62  ? 308 PHE B CE2 1 
ATOM   4582  C  CZ  . PHE B 1 308 ? 17.700  -32.967 2.351   1.00 43.35  ? 308 PHE B CZ  1 
ATOM   4583  N  N   . LEU B 1 309 ? 15.950  -27.416 3.290   1.00 40.86  ? 309 LEU B N   1 
ATOM   4584  C  CA  . LEU B 1 309 ? 14.722  -27.543 4.066   1.00 35.16  ? 309 LEU B CA  1 
ATOM   4585  C  C   . LEU B 1 309 ? 13.534  -26.800 3.427   1.00 37.67  ? 309 LEU B C   1 
ATOM   4586  O  O   . LEU B 1 309 ? 12.405  -27.283 3.576   1.00 37.54  ? 309 LEU B O   1 
ATOM   4587  C  CB  . LEU B 1 309 ? 14.933  -27.064 5.494   1.00 38.37  ? 309 LEU B CB  1 
ATOM   4588  C  CG  . LEU B 1 309 ? 16.072  -27.669 6.306   1.00 37.05  ? 309 LEU B CG  1 
ATOM   4589  C  CD1 . LEU B 1 309 ? 16.309  -26.782 7.472   1.00 35.21  ? 309 LEU B CD1 1 
ATOM   4590  C  CD2 . LEU B 1 309 ? 15.769  -29.059 6.795   1.00 41.44  ? 309 LEU B CD2 1 
ATOM   4591  N  N   . GLU B 1 310 ? 13.748  -25.636 2.760   1.00 44.27  ? 310 GLU B N   1 
ATOM   4592  C  CA  . GLU B 1 310 ? 12.701  -24.854 2.072   1.00 49.45  ? 310 GLU B CA  1 
ATOM   4593  C  C   . GLU B 1 310 ? 11.973  -25.829 1.123   1.00 53.86  ? 310 GLU B C   1 
ATOM   4594  O  O   . GLU B 1 310 ? 10.758  -25.833 1.180   1.00 60.27  ? 310 GLU B O   1 
ATOM   4595  C  CB  . GLU B 1 310 ? 13.228  -23.539 1.421   1.00 59.29  ? 310 GLU B CB  1 
ATOM   4596  C  CG  . GLU B 1 310 ? 12.454  -22.199 1.466   1.00 47.77  ? 310 GLU B CG  1 
ATOM   4597  N  N   . ASP B 1 311 ? 12.654  -26.794 0.427   1.00 61.56  ? 311 ASP B N   1 
ATOM   4598  C  CA  . ASP B 1 311 ? 11.993  -28.006 -0.142  1.00 58.75  ? 311 ASP B CA  1 
ATOM   4599  C  C   . ASP B 1 311 ? 12.039  -29.284 0.732   1.00 51.51  ? 311 ASP B C   1 
ATOM   4600  O  O   . ASP B 1 311 ? 10.969  -29.862 1.075   1.00 53.60  ? 311 ASP B O   1 
ATOM   4601  C  CB  . ASP B 1 311 ? 12.704  -28.499 -1.389  1.00 61.81  ? 311 ASP B CB  1 
ATOM   4602  C  CG  . ASP B 1 311 ? 13.468  -27.463 -2.229  1.00 73.67  ? 311 ASP B CG  1 
ATOM   4603  O  OD1 . ASP B 1 311 ? 13.390  -26.237 -1.946  1.00 53.91  ? 311 ASP B OD1 1 
ATOM   4604  O  OD2 . ASP B 1 311 ? 14.189  -27.892 -3.166  1.00 88.43  ? 311 ASP B OD2 1 
ATOM   4605  N  N   . GLU C 1 7   ? 31.961  -4.374  -10.471 1.00 96.63  ? 7   GLU C N   1 
ATOM   4606  C  CA  . GLU C 1 7   ? 32.445  -2.964  -10.350 1.00 94.92  ? 7   GLU C CA  1 
ATOM   4607  C  C   . GLU C 1 7   ? 31.317  -2.063  -9.719  1.00 112.13 ? 7   GLU C C   1 
ATOM   4608  O  O   . GLU C 1 7   ? 31.644  -1.272  -8.835  1.00 86.81  ? 7   GLU C O   1 
ATOM   4609  C  CB  . GLU C 1 7   ? 33.350  -2.604  -11.574 1.00 54.95  ? 7   GLU C CB  1 
ATOM   4610  N  N   . PRO C 1 8   ? 29.953  -2.122  -9.932  1.00 105.89 ? 8   PRO C N   1 
ATOM   4611  C  CA  . PRO C 1 8   ? 29.078  -0.944  -9.650  1.00 81.61  ? 8   PRO C CA  1 
ATOM   4612  C  C   . PRO C 1 8   ? 28.441  -0.801  -8.246  1.00 59.21  ? 8   PRO C C   1 
ATOM   4613  O  O   . PRO C 1 8   ? 27.905  -1.772  -7.718  1.00 53.94  ? 8   PRO C O   1 
ATOM   4614  C  CB  . PRO C 1 8   ? 28.019  -1.120  -10.767 1.00 80.93  ? 8   PRO C CB  1 
ATOM   4615  C  CG  . PRO C 1 8   ? 27.894  -2.663  -10.906 1.00 87.43  ? 8   PRO C CG  1 
ATOM   4616  C  CD  . PRO C 1 8   ? 29.154  -3.309  -10.299 1.00 91.26  ? 8   PRO C CD  1 
ATOM   4617  N  N   . GLU C 1 9   ? 28.579  0.383   -7.589  1.00 50.24  ? 9   GLU C N   1 
ATOM   4618  C  CA  . GLU C 1 9   ? 28.154  0.619   -6.192  1.00 48.56  ? 9   GLU C CA  1 
ATOM   4619  C  C   . GLU C 1 9   ? 26.652  0.972   -6.301  1.00 43.31  ? 9   GLU C C   1 
ATOM   4620  O  O   . GLU C 1 9   ? 26.282  1.953   -6.948  1.00 33.90  ? 9   GLU C O   1 
ATOM   4621  C  CB  . GLU C 1 9   ? 29.019  1.592   -5.311  1.00 49.70  ? 9   GLU C CB  1 
ATOM   4622  C  CG  . GLU C 1 9   ? 29.851  1.011   -4.137  1.00 45.31  ? 9   GLU C CG  1 
ATOM   4623  N  N   . PRO C 1 10  ? 25.692  0.176   -5.756  1.00 39.13  ? 10  PRO C N   1 
ATOM   4624  C  CA  . PRO C 1 10  ? 24.291  0.612   -5.654  1.00 37.59  ? 10  PRO C CA  1 
ATOM   4625  C  C   . PRO C 1 10  ? 24.110  1.722   -4.631  1.00 31.75  ? 10  PRO C C   1 
ATOM   4626  O  O   . PRO C 1 10  ? 24.935  1.877   -3.757  1.00 24.72  ? 10  PRO C O   1 
ATOM   4627  C  CB  . PRO C 1 10  ? 23.528  -0.648  -5.210  1.00 36.46  ? 10  PRO C CB  1 
ATOM   4628  C  CG  . PRO C 1 10  ? 24.573  -1.395  -4.419  1.00 35.11  ? 10  PRO C CG  1 
ATOM   4629  C  CD  . PRO C 1 10  ? 25.851  -1.190  -5.244  1.00 36.66  ? 10  PRO C CD  1 
ATOM   4630  N  N   . GLN C 1 11  ? 22.999  2.459   -4.731  1.00 32.45  ? 11  GLN C N   1 
ATOM   4631  C  CA  . GLN C 1 11  ? 22.539  3.277   -3.600  1.00 36.96  ? 11  GLN C CA  1 
ATOM   4632  C  C   . GLN C 1 11  ? 22.182  2.363   -2.408  1.00 30.42  ? 11  GLN C C   1 
ATOM   4633  O  O   . GLN C 1 11  ? 22.167  1.144   -2.533  1.00 28.83  ? 11  GLN C O   1 
ATOM   4634  C  CB  . GLN C 1 11  ? 21.378  4.193   -4.016  1.00 28.11  ? 11  GLN C CB  1 
ATOM   4635  C  CG  . GLN C 1 11  ? 21.801  5.195   -5.065  1.00 27.17  ? 11  GLN C CG  1 
ATOM   4636  C  CD  . GLN C 1 11  ? 20.654  6.107   -5.383  1.00 28.03  ? 11  GLN C CD  1 
ATOM   4637  O  OE1 . GLN C 1 11  ? 20.255  6.904   -4.556  1.00 31.00  ? 11  GLN C OE1 1 
ATOM   4638  N  NE2 . GLN C 1 11  ? 20.066  5.988   -6.549  1.00 26.62  ? 11  GLN C NE2 1 
ATOM   4639  N  N   . MET C 1 12  ? 21.815  2.953   -1.281  1.00 28.24  ? 12  MET C N   1 
ATOM   4640  C  CA  . MET C 1 12  ? 21.497  2.176   -0.090  1.00 34.26  ? 12  MET C CA  1 
ATOM   4641  C  C   . MET C 1 12  ? 20.053  1.671   -0.111  1.00 31.88  ? 12  MET C C   1 
ATOM   4642  O  O   . MET C 1 12  ? 19.256  1.864   0.792   1.00 31.72  ? 12  MET C O   1 
ATOM   4643  C  CB  . MET C 1 12  ? 21.717  2.980   1.191   1.00 41.86  ? 12  MET C CB  1 
ATOM   4644  C  CG  . MET C 1 12  ? 21.903  2.114   2.413   1.00 53.13  ? 12  MET C CG  1 
ATOM   4645  S  SD  . MET C 1 12  ? 23.623  1.583   2.319   1.00 65.22  ? 12  MET C SD  1 
ATOM   4646  C  CE  . MET C 1 12  ? 23.236  0.409   3.637   1.00 68.43  ? 12  MET C CE  1 
ATOM   4647  N  N   . VAL C 1 13  ? 19.755  0.894   -1.125  1.00 30.21  ? 13  VAL C N   1 
ATOM   4648  C  CA  . VAL C 1 13  ? 18.451  0.328   -1.237  1.00 30.87  ? 13  VAL C CA  1 
ATOM   4649  C  C   . VAL C 1 13  ? 18.248  -0.661  -0.102  1.00 35.94  ? 13  VAL C C   1 
ATOM   4650  O  O   . VAL C 1 13  ? 17.158  -0.629  0.484   1.00 35.80  ? 13  VAL C O   1 
ATOM   4651  C  CB  . VAL C 1 13  ? 18.299  -0.320  -2.602  1.00 30.07  ? 13  VAL C CB  1 
ATOM   4652  C  CG1 . VAL C 1 13  ? 16.976  -1.035  -2.643  1.00 37.29  ? 13  VAL C CG1 1 
ATOM   4653  C  CG2 . VAL C 1 13  ? 18.380  0.725   -3.693  1.00 35.07  ? 13  VAL C CG2 1 
ATOM   4654  N  N   . LEU C 1 14  ? 19.261  -1.532  0.141   1.00 37.85  ? 14  LEU C N   1 
ATOM   4655  C  CA  . LEU C 1 14  ? 19.199  -2.527  1.211   1.00 37.08  ? 14  LEU C CA  1 
ATOM   4656  C  C   . LEU C 1 14  ? 19.630  -1.842  2.497   1.00 39.04  ? 14  LEU C C   1 
ATOM   4657  O  O   . LEU C 1 14  ? 20.788  -1.690  2.782   1.00 45.78  ? 14  LEU C O   1 
ATOM   4658  C  CB  . LEU C 1 14  ? 20.025  -3.777  0.928   1.00 34.57  ? 14  LEU C CB  1 
ATOM   4659  C  CG  . LEU C 1 14  ? 19.957  -4.281  -0.520  1.00 47.25  ? 14  LEU C CG  1 
ATOM   4660  C  CD1 . LEU C 1 14  ? 21.207  -5.117  -0.867  1.00 64.47  ? 14  LEU C CD1 1 
ATOM   4661  C  CD2 . LEU C 1 14  ? 18.761  -5.136  -0.839  1.00 46.57  ? 14  LEU C CD2 1 
ATOM   4662  N  N   . SER C 1 15  ? 18.705  -1.264  3.210   1.00 39.20  ? 15  SER C N   1 
ATOM   4663  C  CA  . SER C 1 15  ? 19.096  -0.544  4.392   1.00 42.47  ? 15  SER C CA  1 
ATOM   4664  C  C   . SER C 1 15  ? 18.790  -1.451  5.584   1.00 43.61  ? 15  SER C C   1 
ATOM   4665  O  O   . SER C 1 15  ? 17.798  -2.178  5.622   1.00 45.54  ? 15  SER C O   1 
ATOM   4666  C  CB  . SER C 1 15  ? 18.474  0.856   4.430   1.00 37.49  ? 15  SER C CB  1 
ATOM   4667  O  OG  . SER C 1 15  ? 18.363  1.405   5.734   1.00 45.31  ? 15  SER C OG  1 
ATOM   4668  N  N   . PRO C 1 16  ? 19.634  -1.431  6.639   1.00 59.05  ? 16  PRO C N   1 
ATOM   4669  C  CA  . PRO C 1 16  ? 19.174  -1.888  7.946   1.00 50.25  ? 16  PRO C CA  1 
ATOM   4670  C  C   . PRO C 1 16  ? 17.797  -1.302  8.212   1.00 44.64  ? 16  PRO C C   1 
ATOM   4671  O  O   . PRO C 1 16  ? 17.400  -0.279  7.630   1.00 44.70  ? 16  PRO C O   1 
ATOM   4672  C  CB  . PRO C 1 16  ? 20.221  -1.270  8.913   1.00 56.95  ? 16  PRO C CB  1 
ATOM   4673  C  CG  . PRO C 1 16  ? 21.116  -0.299  8.077   1.00 54.58  ? 16  PRO C CG  1 
ATOM   4674  C  CD  . PRO C 1 16  ? 21.004  -0.848  6.667   1.00 62.26  ? 16  PRO C CD  1 
ATOM   4675  N  N   . LEU C 1 17  ? 17.137  -1.898  9.194   1.00 49.86  ? 17  LEU C N   1 
ATOM   4676  C  CA  . LEU C 1 17  ? 15.939  -1.335  9.813   1.00 50.16  ? 17  LEU C CA  1 
ATOM   4677  C  C   . LEU C 1 17  ? 16.279  0.056   10.379  1.00 40.28  ? 17  LEU C C   1 
ATOM   4678  O  O   . LEU C 1 17  ? 17.338  0.302   10.993  1.00 37.62  ? 17  LEU C O   1 
ATOM   4679  C  CB  . LEU C 1 17  ? 15.336  -2.264  10.884  1.00 47.74  ? 17  LEU C CB  1 
ATOM   4680  C  CG  . LEU C 1 17  ? 14.999  -3.718  10.503  1.00 53.47  ? 17  LEU C CG  1 
ATOM   4681  C  CD1 . LEU C 1 17  ? 14.338  -4.355  11.762  1.00 62.13  ? 17  LEU C CD1 1 
ATOM   4682  C  CD2 . LEU C 1 17  ? 14.164  -3.905  9.166   1.00 43.88  ? 17  LEU C CD2 1 
ATOM   4683  N  N   . THR C 1 18  ? 15.387  0.989   10.047  1.00 30.93  ? 18  THR C N   1 
ATOM   4684  C  CA  . THR C 1 18  ? 15.484  2.383   10.438  1.00 34.01  ? 18  THR C CA  1 
ATOM   4685  C  C   . THR C 1 18  ? 14.102  2.735   10.997  1.00 31.60  ? 18  THR C C   1 
ATOM   4686  O  O   . THR C 1 18  ? 13.084  2.170   10.667  1.00 31.92  ? 18  THR C O   1 
ATOM   4687  C  CB  . THR C 1 18  ? 15.872  3.250   9.232   1.00 36.93  ? 18  THR C CB  1 
ATOM   4688  O  OG1 . THR C 1 18  ? 15.112  2.829   8.100   1.00 49.01  ? 18  THR C OG1 1 
ATOM   4689  C  CG2 . THR C 1 18  ? 17.308  3.110   8.765   1.00 40.03  ? 18  THR C CG2 1 
ATOM   4690  N  N   . SER C 1 19  ? 14.020  3.684   11.885  1.00 31.68  ? 19  SER C N   1 
ATOM   4691  C  CA  . SER C 1 19  ? 12.776  3.933   12.570  1.00 28.90  ? 19  SER C CA  1 
ATOM   4692  C  C   . SER C 1 19  ? 12.173  5.275   12.157  1.00 23.31  ? 19  SER C C   1 
ATOM   4693  O  O   . SER C 1 19  ? 11.075  5.579   12.565  1.00 27.85  ? 19  SER C O   1 
ATOM   4694  C  CB  . SER C 1 19  ? 13.002  3.792   14.052  1.00 34.17  ? 19  SER C CB  1 
ATOM   4695  O  OG  . SER C 1 19  ? 14.270  4.335   14.297  1.00 39.46  ? 19  SER C OG  1 
ATOM   4696  N  N   . ALA C 1 20  ? 12.819  6.021   11.274  1.00 21.02  ? 20  ALA C N   1 
ATOM   4697  C  CA  . ALA C 1 20  ? 12.228  7.240   10.742  1.00 21.51  ? 20  ALA C CA  1 
ATOM   4698  C  C   . ALA C 1 20  ? 12.519  7.349   9.259   1.00 20.64  ? 20  ALA C C   1 
ATOM   4699  O  O   . ALA C 1 20  ? 13.554  6.885   8.811   1.00 20.42  ? 20  ALA C O   1 
ATOM   4700  C  CB  . ALA C 1 20  ? 12.780  8.441   11.384  1.00 21.15  ? 20  ALA C CB  1 
ATOM   4701  N  N   . ALA C 1 21  ? 11.578  7.913   8.513   1.00 21.56  ? 21  ALA C N   1 
ATOM   4702  C  CA  . ALA C 1 21  ? 11.800  8.158   7.104   1.00 21.64  ? 21  ALA C CA  1 
ATOM   4703  C  C   . ALA C 1 21  ? 11.120  9.465   6.693   1.00 20.64  ? 21  ALA C C   1 
ATOM   4704  O  O   . ALA C 1 21  ? 10.108  9.851   7.272   1.00 21.85  ? 21  ALA C O   1 
ATOM   4705  C  CB  . ALA C 1 21  ? 11.275  7.006   6.321   1.00 21.19  ? 21  ALA C CB  1 
ATOM   4706  N  N   . ILE C 1 22  ? 11.715  10.124  5.691   1.00 19.88  ? 22  ILE C N   1 
ATOM   4707  C  CA  . ILE C 1 22  ? 11.022  11.138  4.934   1.00 20.50  ? 22  ILE C CA  1 
ATOM   4708  C  C   . ILE C 1 22  ? 10.942  10.715  3.476   1.00 20.02  ? 22  ILE C C   1 
ATOM   4709  O  O   . ILE C 1 22  ? 11.935  10.328  2.902   1.00 21.53  ? 22  ILE C O   1 
ATOM   4710  C  CB  . ILE C 1 22  ? 11.688  12.496  5.108   1.00 20.84  ? 22  ILE C CB  1 
ATOM   4711  C  CG1 . ILE C 1 22  ? 11.518  12.979  6.507   1.00 25.27  ? 22  ILE C CG1 1 
ATOM   4712  C  CG2 . ILE C 1 22  ? 11.146  13.492  4.077   1.00 22.00  ? 22  ILE C CG2 1 
ATOM   4713  C  CD1 . ILE C 1 22  ? 12.096  14.372  6.770   1.00 27.55  ? 22  ILE C CD1 1 
ATOM   4714  N  N   . PHE C 1 23  ? 9.746   10.794  2.902   1.00 19.51  ? 23  PHE C N   1 
ATOM   4715  C  CA  . PHE C 1 23  ? 9.539   10.566  1.486   1.00 19.62  ? 23  PHE C CA  1 
ATOM   4716  C  C   . PHE C 1 23  ? 9.196   11.899  0.856   1.00 19.84  ? 23  PHE C C   1 
ATOM   4717  O  O   . PHE C 1 23  ? 8.248   12.555  1.256   1.00 20.61  ? 23  PHE C O   1 
ATOM   4718  C  CB  . PHE C 1 23  ? 8.357   9.627   1.237   1.00 20.41  ? 23  PHE C CB  1 
ATOM   4719  C  CG  . PHE C 1 23  ? 8.457   8.293   1.910   1.00 21.59  ? 23  PHE C CG  1 
ATOM   4720  C  CD1 . PHE C 1 23  ? 9.125   7.247   1.298   1.00 22.47  ? 23  PHE C CD1 1 
ATOM   4721  C  CD2 . PHE C 1 23  ? 7.936   8.104   3.183   1.00 23.82  ? 23  PHE C CD2 1 
ATOM   4722  C  CE1 . PHE C 1 23  ? 9.232   6.009   1.928   1.00 22.79  ? 23  PHE C CE1 1 
ATOM   4723  C  CE2 . PHE C 1 23  ? 8.083   6.859   3.822   1.00 24.69  ? 23  PHE C CE2 1 
ATOM   4724  C  CZ  . PHE C 1 23  ? 8.730   5.823   3.194   1.00 20.89  ? 23  PHE C CZ  1 
ATOM   4725  N  N   . LEU C 1 24  ? 9.967   12.278  -0.130  1.00 21.05  ? 24  LEU C N   1 
ATOM   4726  C  CA  . LEU C 1 24  ? 9.793   13.534  -0.832  1.00 21.95  ? 24  LEU C CA  1 
ATOM   4727  C  C   . LEU C 1 24  ? 9.645   13.271  -2.333  1.00 20.00  ? 24  LEU C C   1 
ATOM   4728  O  O   . LEU C 1 24  ? 10.468  12.640  -2.944  1.00 20.34  ? 24  LEU C O   1 
ATOM   4729  C  CB  . LEU C 1 24  ? 11.037  14.325  -0.497  1.00 25.66  ? 24  LEU C CB  1 
ATOM   4730  C  CG  . LEU C 1 24  ? 10.994  15.827  -0.656  1.00 31.45  ? 24  LEU C CG  1 
ATOM   4731  C  CD1 . LEU C 1 24  ? 9.806   16.526  -0.030  1.00 37.28  ? 24  LEU C CD1 1 
ATOM   4732  C  CD2 . LEU C 1 24  ? 12.283  16.213  0.027   1.00 37.16  ? 24  LEU C CD2 1 
ATOM   4733  N  N   . VAL C 1 25  ? 8.549   13.735  -2.915  1.00 20.19  ? 25  VAL C N   1 
ATOM   4734  C  CA  . VAL C 1 25  ? 8.267   13.539  -4.318  1.00 19.83  ? 25  VAL C CA  1 
ATOM   4735  C  C   . VAL C 1 25  ? 8.049   14.899  -4.919  1.00 18.12  ? 25  VAL C C   1 
ATOM   4736  O  O   . VAL C 1 25  ? 7.226   15.631  -4.407  1.00 19.10  ? 25  VAL C O   1 
ATOM   4737  C  CB  . VAL C 1 25  ? 7.064   12.622  -4.610  1.00 22.28  ? 25  VAL C CB  1 
ATOM   4738  C  CG1 . VAL C 1 25  ? 6.762   12.502  -6.091  1.00 22.53  ? 25  VAL C CG1 1 
ATOM   4739  C  CG2 . VAL C 1 25  ? 7.292   11.227  -4.062  1.00 22.01  ? 25  VAL C CG2 1 
ATOM   4740  N  N   . VAL C 1 26  ? 8.835   15.208  -5.943  1.00 17.74  ? 26  VAL C N   1 
ATOM   4741  C  CA  . VAL C 1 26  ? 8.749   16.507  -6.566  1.00 19.75  ? 26  VAL C CA  1 
ATOM   4742  C  C   . VAL C 1 26  ? 8.605   16.338  -8.069  1.00 20.44  ? 26  VAL C C   1 
ATOM   4743  O  O   . VAL C 1 26  ? 9.053   15.326  -8.634  1.00 18.18  ? 26  VAL C O   1 
ATOM   4744  C  CB  . VAL C 1 26  ? 9.974   17.381  -6.242  1.00 21.42  ? 26  VAL C CB  1 
ATOM   4745  C  CG1 . VAL C 1 26  ? 10.249  17.487  -4.756  1.00 23.15  ? 26  VAL C CG1 1 
ATOM   4746  C  CG2 . VAL C 1 26  ? 11.233  16.830  -6.871  1.00 26.88  ? 26  VAL C CG2 1 
ATOM   4747  N  N   . THR C 1 27  ? 8.096   17.411  -8.712  1.00 22.84  ? 27  THR C N   1 
ATOM   4748  C  CA  . THR C 1 27  ? 8.217   17.574  -10.162 1.00 22.84  ? 27  THR C CA  1 
ATOM   4749  C  C   . THR C 1 27  ? 9.243   18.648  -10.493 1.00 20.64  ? 27  THR C C   1 
ATOM   4750  O  O   . THR C 1 27  ? 9.418   19.603  -9.758  1.00 22.82  ? 27  THR C O   1 
ATOM   4751  C  CB  . THR C 1 27  ? 6.860   17.853  -10.809 1.00 21.25  ? 27  THR C CB  1 
ATOM   4752  O  OG1 . THR C 1 27  ? 6.309   19.007  -10.176 1.00 23.23  ? 27  THR C OG1 1 
ATOM   4753  C  CG2 . THR C 1 27  ? 5.969   16.640  -10.664 1.00 22.95  ? 27  THR C CG2 1 
ATOM   4754  N  N   . ILE C 1 28  ? 9.913   18.426  -11.613 1.00 21.11  ? 28  ILE C N   1 
ATOM   4755  C  CA  . ILE C 1 28  ? 10.858  19.344  -12.202 1.00 25.38  ? 28  ILE C CA  1 
ATOM   4756  C  C   . ILE C 1 28  ? 10.125  20.409  -13.063 1.00 28.17  ? 28  ILE C C   1 
ATOM   4757  O  O   . ILE C 1 28  ? 9.460   20.118  -14.063 1.00 29.79  ? 28  ILE C O   1 
ATOM   4758  C  CB  . ILE C 1 28  ? 11.931  18.592  -13.019 1.00 24.59  ? 28  ILE C CB  1 
ATOM   4759  C  CG1 . ILE C 1 28  ? 12.600  17.486  -12.205 1.00 24.26  ? 28  ILE C CG1 1 
ATOM   4760  C  CG2 . ILE C 1 28  ? 12.961  19.611  -13.524 1.00 25.18  ? 28  ILE C CG2 1 
ATOM   4761  C  CD1 . ILE C 1 28  ? 13.531  16.613  -13.020 1.00 24.59  ? 28  ILE C CD1 1 
ATOM   4762  N  N   . ASP C 1 29  ? 10.274  21.675  -12.671 1.00 24.50  ? 29  ASP C N   1 
ATOM   4763  C  CA  . ASP C 1 29  ? 9.709   22.774  -13.415 1.00 26.87  ? 29  ASP C CA  1 
ATOM   4764  C  C   . ASP C 1 29  ? 10.421  22.885  -14.766 1.00 25.98  ? 29  ASP C C   1 
ATOM   4765  O  O   . ASP C 1 29  ? 11.538  22.437  -14.906 1.00 27.81  ? 29  ASP C O   1 
ATOM   4766  C  CB  . ASP C 1 29  ? 9.879   24.070  -12.629 1.00 30.11  ? 29  ASP C CB  1 
ATOM   4767  C  CG  . ASP C 1 29  ? 9.203   24.092  -11.272 1.00 27.24  ? 29  ASP C CG  1 
ATOM   4768  O  OD1 . ASP C 1 29  ? 8.501   23.151  -10.929 1.00 27.10  ? 29  ASP C OD1 1 
ATOM   4769  O  OD2 . ASP C 1 29  ? 9.428   25.061  -10.601 1.00 31.78  ? 29  ASP C OD2 1 
ATOM   4770  N  N   . SER C 1 30  ? 9.795   23.514  -15.749 1.00 30.55  ? 30  SER C N   1 
ATOM   4771  C  CA  . SER C 1 30  ? 10.441  23.935  -16.982 1.00 32.72  ? 30  SER C CA  1 
ATOM   4772  C  C   . SER C 1 30  ? 11.683  24.729  -16.653 1.00 31.29  ? 30  SER C C   1 
ATOM   4773  O  O   . SER C 1 30  ? 11.623  25.693  -15.888 1.00 34.62  ? 30  SER C O   1 
ATOM   4774  C  CB  . SER C 1 30  ? 9.561   24.897  -17.792 1.00 45.23  ? 30  SER C CB  1 
ATOM   4775  O  OG  . SER C 1 30  ? 8.646   24.243  -18.674 1.00 61.13  ? 30  SER C OG  1 
ATOM   4776  N  N   . GLY C 1 31  ? 12.809  24.364  -17.256 1.00 29.60  ? 31  GLY C N   1 
ATOM   4777  C  CA  . GLY C 1 31  ? 13.992  25.158  -17.025 1.00 27.08  ? 31  GLY C CA  1 
ATOM   4778  C  C   . GLY C 1 31  ? 14.797  24.652  -15.824 1.00 32.92  ? 31  GLY C C   1 
ATOM   4779  O  O   . GLY C 1 31  ? 15.915  25.123  -15.630 1.00 33.09  ? 31  GLY C O   1 
ATOM   4780  N  N   . GLY C 1 32  ? 14.295  23.656  -15.069 1.00 27.10  ? 32  GLY C N   1 
ATOM   4781  C  CA  . GLY C 1 32  ? 14.967  23.248  -13.843 1.00 29.43  ? 32  GLY C CA  1 
ATOM   4782  C  C   . GLY C 1 32  ? 16.058  22.203  -14.026 1.00 27.64  ? 32  GLY C C   1 
ATOM   4783  O  O   . GLY C 1 32  ? 16.738  21.849  -13.063 1.00 28.57  ? 32  GLY C O   1 
ATOM   4784  N  N   . GLU C 1 33  ? 16.211  21.681  -15.250 1.00 28.50  ? 33  GLU C N   1 
ATOM   4785  C  CA  . GLU C 1 33  ? 16.961  20.448  -15.439 1.00 28.56  ? 33  GLU C CA  1 
ATOM   4786  C  C   . GLU C 1 33  ? 18.427  20.577  -14.999 1.00 29.86  ? 33  GLU C C   1 
ATOM   4787  O  O   . GLU C 1 33  ? 19.034  19.616  -14.503 1.00 29.97  ? 33  GLU C O   1 
ATOM   4788  C  CB  . GLU C 1 33  ? 16.841  19.973  -16.889 1.00 28.01  ? 33  GLU C CB  1 
ATOM   4789  C  CG  . GLU C 1 33  ? 15.468  19.526  -17.359 1.00 29.37  ? 33  GLU C CG  1 
ATOM   4790  C  CD  . GLU C 1 33  ? 14.494  20.602  -17.834 1.00 32.32  ? 33  GLU C CD  1 
ATOM   4791  O  OE1 . GLU C 1 33  ? 14.764  21.803  -17.709 1.00 34.51  ? 33  GLU C OE1 1 
ATOM   4792  O  OE2 . GLU C 1 33  ? 13.420  20.200  -18.365 1.00 41.34  ? 33  GLU C OE2 1 
ATOM   4793  N  N   . ASP C 1 34  ? 19.064  21.714  -15.274 1.00 30.91  ? 34  ASP C N   1 
ATOM   4794  C  CA  . ASP C 1 34  ? 20.477  21.865  -14.932 1.00 34.88  ? 34  ASP C CA  1 
ATOM   4795  C  C   . ASP C 1 34  ? 20.681  21.892  -13.417 1.00 35.34  ? 34  ASP C C   1 
ATOM   4796  O  O   . ASP C 1 34  ? 21.616  21.272  -12.904 1.00 29.07  ? 34  ASP C O   1 
ATOM   4797  C  CB  . ASP C 1 34  ? 21.090  23.162  -15.430 1.00 42.28  ? 34  ASP C CB  1 
ATOM   4798  C  CG  . ASP C 1 34  ? 21.281  23.210  -16.944 1.00 56.77  ? 34  ASP C CG  1 
ATOM   4799  O  OD1 . ASP C 1 34  ? 21.663  22.160  -17.514 1.00 45.67  ? 34  ASP C OD1 1 
ATOM   4800  O  OD2 . ASP C 1 34  ? 21.017  24.283  -17.536 1.00 67.42  ? 34  ASP C OD2 1 
ATOM   4801  N  N   . THR C 1 35  ? 19.831  22.651  -12.709 1.00 27.24  ? 35  THR C N   1 
ATOM   4802  C  CA  . THR C 1 35  ? 19.896  22.669  -11.267 1.00 27.17  ? 35  THR C CA  1 
ATOM   4803  C  C   . THR C 1 35  ? 19.771  21.256  -10.697 1.00 27.41  ? 35  THR C C   1 
ATOM   4804  O  O   . THR C 1 35  ? 20.489  20.906  -9.777  1.00 23.65  ? 35  THR C O   1 
ATOM   4805  C  CB  . THR C 1 35  ? 18.760  23.533  -10.742 1.00 27.33  ? 35  THR C CB  1 
ATOM   4806  O  OG1 . THR C 1 35  ? 19.061  24.826  -11.193 1.00 27.30  ? 35  THR C OG1 1 
ATOM   4807  C  CG2 . THR C 1 35  ? 18.787  23.635  -9.236  1.00 26.36  ? 35  THR C CG2 1 
ATOM   4808  N  N   . VAL C 1 36  ? 18.832  20.469  -11.237 1.00 27.69  ? 36  VAL C N   1 
ATOM   4809  C  CA  . VAL C 1 36  ? 18.636  19.114  -10.774 1.00 26.77  ? 36  VAL C CA  1 
ATOM   4810  C  C   . VAL C 1 36  ? 19.872  18.281  -11.052 1.00 26.56  ? 36  VAL C C   1 
ATOM   4811  O  O   . VAL C 1 36  ? 20.344  17.544  -10.196 1.00 25.76  ? 36  VAL C O   1 
ATOM   4812  C  CB  . VAL C 1 36  ? 17.391  18.486  -11.405 1.00 32.21  ? 36  VAL C CB  1 
ATOM   4813  C  CG1 . VAL C 1 36  ? 17.311  16.969  -11.153 1.00 33.70  ? 36  VAL C CG1 1 
ATOM   4814  C  CG2 . VAL C 1 36  ? 16.098  19.160  -10.933 1.00 30.84  ? 36  VAL C CG2 1 
ATOM   4815  N  N   . ARG C 1 37  ? 20.435  18.378  -12.238 1.00 29.36  ? 37  ARG C N   1 
ATOM   4816  C  CA  . ARG C 1 37  ? 21.603  17.554  -12.529 1.00 34.30  ? 37  ARG C CA  1 
ATOM   4817  C  C   . ARG C 1 37  ? 22.797  17.851  -11.615 1.00 31.98  ? 37  ARG C C   1 
ATOM   4818  O  O   . ARG C 1 37  ? 23.537  16.911  -11.230 1.00 32.94  ? 37  ARG C O   1 
ATOM   4819  C  CB  . ARG C 1 37  ? 22.151  17.733  -13.941 1.00 39.56  ? 37  ARG C CB  1 
ATOM   4820  C  CG  . ARG C 1 37  ? 21.545  16.879  -15.035 1.00 46.64  ? 37  ARG C CG  1 
ATOM   4821  C  CD  . ARG C 1 37  ? 22.504  16.813  -16.274 1.00 52.86  ? 37  ARG C CD  1 
ATOM   4822  N  NE  . ARG C 1 37  ? 21.605  16.976  -17.416 1.00 55.20  ? 37  ARG C NE  1 
ATOM   4823  C  CZ  . ARG C 1 37  ? 20.885  18.083  -17.744 1.00 55.47  ? 37  ARG C CZ  1 
ATOM   4824  N  NH1 . ARG C 1 37  ? 21.264  19.309  -17.415 1.00 55.57  ? 37  ARG C NH1 1 
ATOM   4825  N  NH2 . ARG C 1 37  ? 19.810  17.956  -18.519 1.00 62.49  ? 37  ARG C NH2 1 
ATOM   4826  N  N   . ASP C 1 38  ? 23.017  19.134  -11.268 1.00 29.16  ? 38  ASP C N   1 
ATOM   4827  C  CA  . ASP C 1 38  ? 24.078  19.454  -10.310 1.00 31.86  ? 38  ASP C CA  1 
ATOM   4828  C  C   . ASP C 1 38  ? 23.796  18.783  -8.960  1.00 31.02  ? 38  ASP C C   1 
ATOM   4829  O  O   . ASP C 1 38  ? 24.701  18.232  -8.345  1.00 31.81  ? 38  ASP C O   1 
ATOM   4830  C  CB  . ASP C 1 38  ? 24.157  20.911  -9.894  1.00 38.36  ? 38  ASP C CB  1 
ATOM   4831  C  CG  . ASP C 1 38  ? 24.810  21.876  -10.841 1.00 53.26  ? 38  ASP C CG  1 
ATOM   4832  O  OD1 . ASP C 1 38  ? 25.523  21.413  -11.752 1.00 56.78  ? 38  ASP C OD1 1 
ATOM   4833  O  OD2 . ASP C 1 38  ? 24.559  23.081  -10.638 1.00 81.85  ? 38  ASP C OD2 1 
ATOM   4834  N  N   . LEU C 1 39  ? 22.541  18.868  -8.495  1.00 29.12  ? 39  LEU C N   1 
ATOM   4835  C  CA  . LEU C 1 39  ? 22.196  18.308  -7.220  1.00 26.43  ? 39  LEU C CA  1 
ATOM   4836  C  C   . LEU C 1 39  ? 22.396  16.779  -7.218  1.00 29.69  ? 39  LEU C C   1 
ATOM   4837  O  O   . LEU C 1 39  ? 22.839  16.199  -6.201  1.00 26.18  ? 39  LEU C O   1 
ATOM   4838  C  CB  . LEU C 1 39  ? 20.770  18.696  -6.857  1.00 27.07  ? 39  LEU C CB  1 
ATOM   4839  C  CG  . LEU C 1 39  ? 20.439  17.866  -5.623  1.00 33.67  ? 39  LEU C CG  1 
ATOM   4840  C  CD1 . LEU C 1 39  ? 20.574  18.655  -4.364  1.00 37.58  ? 39  LEU C CD1 1 
ATOM   4841  C  CD2 . LEU C 1 39  ? 19.265  17.033  -5.776  1.00 33.36  ? 39  LEU C CD2 1 
ATOM   4842  N  N   . LEU C 1 40  ? 22.013  16.089  -8.318  1.00 25.27  ? 40  LEU C N   1 
ATOM   4843  C  CA  . LEU C 1 40  ? 22.151  14.646  -8.320  1.00 25.10  ? 40  LEU C CA  1 
ATOM   4844  C  C   . LEU C 1 40  ? 23.626  14.253  -8.083  1.00 30.25  ? 40  LEU C C   1 
ATOM   4845  O  O   . LEU C 1 40  ? 23.997  13.205  -7.509  1.00 25.99  ? 40  LEU C O   1 
ATOM   4846  C  CB  . LEU C 1 40  ? 21.627  14.129  -9.651  1.00 25.94  ? 40  LEU C CB  1 
ATOM   4847  C  CG  . LEU C 1 40  ? 20.136  14.268  -9.902  1.00 30.60  ? 40  LEU C CG  1 
ATOM   4848  C  CD1 . LEU C 1 40  ? 19.751  13.788  -11.280 1.00 28.65  ? 40  LEU C CD1 1 
ATOM   4849  C  CD2 . LEU C 1 40  ? 19.360  13.458  -8.862  1.00 35.98  ? 40  LEU C CD2 1 
ATOM   4850  N  N   . SER C 1 41  ? 24.535  15.043  -8.649  1.00 33.42  ? 41  SER C N   1 
ATOM   4851  C  CA  . SER C 1 41  ? 25.925  14.627  -8.568  1.00 40.55  ? 41  SER C CA  1 
ATOM   4852  C  C   . SER C 1 41  ? 26.479  14.886  -7.157  1.00 40.86  ? 41  SER C C   1 
ATOM   4853  O  O   . SER C 1 41  ? 27.499  14.324  -6.785  1.00 44.01  ? 41  SER C O   1 
ATOM   4854  C  CB  . SER C 1 41  ? 26.778  15.285  -9.628  1.00 41.67  ? 41  SER C CB  1 
ATOM   4855  O  OG  . SER C 1 41  ? 26.917  16.652  -9.295  1.00 40.19  ? 41  SER C OG  1 
ATOM   4856  N  N   . ASP C 1 42  ? 25.786  15.689  -6.345  1.00 33.55  ? 42  ASP C N   1 
ATOM   4857  C  CA  . ASP C 1 42  ? 26.239  16.008  -5.008  1.00 36.12  ? 42  ASP C CA  1 
ATOM   4858  C  C   . ASP C 1 42  ? 25.469  15.337  -3.873  1.00 29.33  ? 42  ASP C C   1 
ATOM   4859  O  O   . ASP C 1 42  ? 25.791  15.556  -2.706  1.00 24.07  ? 42  ASP C O   1 
ATOM   4860  C  CB  . ASP C 1 42  ? 26.001  17.485  -4.830  1.00 34.95  ? 42  ASP C CB  1 
ATOM   4861  C  CG  . ASP C 1 42  ? 27.102  18.339  -5.387  1.00 40.04  ? 42  ASP C CG  1 
ATOM   4862  O  OD1 . ASP C 1 42  ? 28.226  17.795  -5.476  1.00 47.91  ? 42  ASP C OD1 1 
ATOM   4863  O  OD2 . ASP C 1 42  ? 26.807  19.519  -5.586  1.00 40.96  ? 42  ASP C OD2 1 
ATOM   4864  N  N   . VAL C 1 43  ? 24.408  14.591  -4.202  1.00 29.79  ? 43  VAL C N   1 
ATOM   4865  C  CA  . VAL C 1 43  ? 23.503  14.147  -3.149  1.00 28.91  ? 43  VAL C CA  1 
ATOM   4866  C  C   . VAL C 1 43  ? 24.255  13.179  -2.216  1.00 27.01  ? 43  VAL C C   1 
ATOM   4867  O  O   . VAL C 1 43  ? 24.036  13.240  -1.021  1.00 21.79  ? 43  VAL C O   1 
ATOM   4868  C  CB  . VAL C 1 43  ? 22.178  13.607  -3.758  1.00 28.44  ? 43  VAL C CB  1 
ATOM   4869  C  CG1 . VAL C 1 43  ? 22.384  12.271  -4.377  1.00 34.50  ? 43  VAL C CG1 1 
ATOM   4870  C  CG2 . VAL C 1 43  ? 21.124  13.275  -2.746  1.00 35.24  ? 43  VAL C CG2 1 
ATOM   4871  N  N   . ALA C 1 44  ? 25.196  12.346  -2.728  1.00 25.46  ? 44  ALA C N   1 
ATOM   4872  C  CA  . ALA C 1 44  ? 25.979  11.476  -1.854  1.00 24.55  ? 44  ALA C CA  1 
ATOM   4873  C  C   . ALA C 1 44  ? 26.849  12.284  -0.903  1.00 26.43  ? 44  ALA C C   1 
ATOM   4874  O  O   . ALA C 1 44  ? 27.029  11.946  0.274   1.00 26.66  ? 44  ALA C O   1 
ATOM   4875  C  CB  . ALA C 1 44  ? 26.834  10.567  -2.669  1.00 23.34  ? 44  ALA C CB  1 
ATOM   4876  N  N   . SER C 1 45  ? 27.398  13.409  -1.379  1.00 25.75  ? 45  SER C N   1 
ATOM   4877  C  CA  . SER C 1 45  ? 28.226  14.242  -0.531  1.00 25.59  ? 45  SER C CA  1 
ATOM   4878  C  C   . SER C 1 45  ? 27.395  14.797  0.595   1.00 25.14  ? 45  SER C C   1 
ATOM   4879  O  O   . SER C 1 45  ? 27.931  15.028  1.678   1.00 21.94  ? 45  SER C O   1 
ATOM   4880  C  CB  . SER C 1 45  ? 28.733  15.483  -1.111  1.00 26.34  ? 45  SER C CB  1 
ATOM   4881  O  OG  . SER C 1 45  ? 29.201  15.298  -2.376  1.00 34.62  ? 45  SER C OG  1 
ATOM   4882  N  N   . LEU C 1 46  ? 26.160  15.224  0.243   1.00 23.56  ? 46  LEU C N   1 
ATOM   4883  C  CA  . LEU C 1 46  ? 25.324  15.841  1.263   1.00 24.09  ? 46  LEU C CA  1 
ATOM   4884  C  C   . LEU C 1 46  ? 24.905  14.811  2.325   1.00 22.94  ? 46  LEU C C   1 
ATOM   4885  O  O   . LEU C 1 46  ? 24.767  15.111  3.493   1.00 22.27  ? 46  LEU C O   1 
ATOM   4886  C  CB  . LEU C 1 46  ? 24.140  16.473  0.549   1.00 24.79  ? 46  LEU C CB  1 
ATOM   4887  C  CG  . LEU C 1 46  ? 24.445  17.664  -0.321  1.00 24.71  ? 46  LEU C CG  1 
ATOM   4888  C  CD1 . LEU C 1 46  ? 23.186  18.054  -1.021  1.00 26.51  ? 46  LEU C CD1 1 
ATOM   4889  C  CD2 . LEU C 1 46  ? 24.995  18.776  0.532   1.00 27.97  ? 46  LEU C CD2 1 
ATOM   4890  N  N   . GLU C 1 47  ? 24.696  13.572  1.908   1.00 22.50  ? 47  GLU C N   1 
ATOM   4891  C  CA  . GLU C 1 47  ? 24.350  12.501  2.816   1.00 23.13  ? 47  GLU C CA  1 
ATOM   4892  C  C   . GLU C 1 47  ? 25.504  12.338  3.795   1.00 23.41  ? 47  GLU C C   1 
ATOM   4893  O  O   . GLU C 1 47  ? 25.283  12.185  4.968   1.00 20.27  ? 47  GLU C O   1 
ATOM   4894  C  CB  . GLU C 1 47  ? 24.055  11.300  1.905   1.00 28.39  ? 47  GLU C CB  1 
ATOM   4895  C  CG  . GLU C 1 47  ? 23.692  10.062  2.674   1.00 32.10  ? 47  GLU C CG  1 
ATOM   4896  C  CD  . GLU C 1 47  ? 23.720  8.855   1.799   1.00 37.23  ? 47  GLU C CD  1 
ATOM   4897  O  OE1 . GLU C 1 47  ? 22.780  8.526   1.140   1.00 36.86  ? 47  GLU C OE1 1 
ATOM   4898  O  OE2 . GLU C 1 47  ? 24.725  8.203   1.860   1.00 49.51  ? 47  GLU C OE2 1 
ATOM   4899  N  N   . ARG C 1 48  ? 26.753  12.374  3.334   1.00 26.88  ? 48  ARG C N   1 
ATOM   4900  C  CA  . ARG C 1 48  ? 27.898  12.297  4.244   1.00 27.06  ? 48  ARG C CA  1 
ATOM   4901  C  C   . ARG C 1 48  ? 28.018  13.534  5.131   1.00 24.71  ? 48  ARG C C   1 
ATOM   4902  O  O   . ARG C 1 48  ? 28.297  13.437  6.321   1.00 25.73  ? 48  ARG C O   1 
ATOM   4903  C  CB  . ARG C 1 48  ? 29.260  12.130  3.561   1.00 24.64  ? 48  ARG C CB  1 
ATOM   4904  C  CG  . ARG C 1 48  ? 29.308  10.780  2.891   1.00 26.44  ? 48  ARG C CG  1 
ATOM   4905  C  CD  . ARG C 1 48  ? 30.644  10.379  2.434   1.00 29.28  ? 48  ARG C CD  1 
ATOM   4906  N  NE  . ARG C 1 48  ? 31.177  11.343  1.469   1.00 35.30  ? 48  ARG C NE  1 
ATOM   4907  C  CZ  . ARG C 1 48  ? 30.980  11.353  0.128   1.00 41.39  ? 48  ARG C CZ  1 
ATOM   4908  N  NH1 . ARG C 1 48  ? 30.236  10.436  -0.492  1.00 36.46  ? 48  ARG C NH1 1 
ATOM   4909  N  NH2 . ARG C 1 48  ? 31.484  12.343  -0.600  1.00 41.96  ? 48  ARG C NH2 1 
ATOM   4910  N  N   . ALA C 1 49  ? 27.821  14.726  4.588   1.00 21.69  ? 49  ALA C N   1 
ATOM   4911  C  CA  . ALA C 1 49  ? 27.982  15.915  5.386   1.00 21.10  ? 49  ALA C CA  1 
ATOM   4912  C  C   . ALA C 1 49  ? 27.015  15.862  6.549   1.00 24.19  ? 49  ALA C C   1 
ATOM   4913  O  O   . ALA C 1 49  ? 27.410  16.175  7.650   1.00 28.41  ? 49  ALA C O   1 
ATOM   4914  C  CB  . ALA C 1 49  ? 27.741  17.132  4.528   1.00 23.17  ? 49  ALA C CB  1 
ATOM   4915  N  N   . VAL C 1 50  ? 25.739  15.517  6.300   1.00 22.27  ? 50  VAL C N   1 
ATOM   4916  C  CA  . VAL C 1 50  ? 24.749  15.530  7.362   1.00 25.63  ? 50  VAL C CA  1 
ATOM   4917  C  C   . VAL C 1 50  ? 24.968  14.337  8.274   1.00 24.17  ? 50  VAL C C   1 
ATOM   4918  O  O   . VAL C 1 50  ? 24.807  14.469  9.479   1.00 25.71  ? 50  VAL C O   1 
ATOM   4919  C  CB  . VAL C 1 50  ? 23.301  15.567  6.838   1.00 27.94  ? 50  VAL C CB  1 
ATOM   4920  C  CG1 . VAL C 1 50  ? 22.270  15.376  7.942   1.00 30.02  ? 50  VAL C CG1 1 
ATOM   4921  C  CG2 . VAL C 1 50  ? 23.050  16.865  6.091   1.00 28.79  ? 50  VAL C CG2 1 
ATOM   4922  N  N   . GLY C 1 51  ? 25.300  13.192  7.687   1.00 23.25  ? 51  GLY C N   1 
ATOM   4923  C  CA  . GLY C 1 51  ? 25.195  11.956  8.436   1.00 28.44  ? 51  GLY C CA  1 
ATOM   4924  C  C   . GLY C 1 51  ? 26.472  11.589  9.198   1.00 31.89  ? 51  GLY C C   1 
ATOM   4925  O  O   . GLY C 1 51  ? 26.398  10.941  10.211  1.00 27.98  ? 51  GLY C O   1 
ATOM   4926  N  N   . PHE C 1 52  ? 27.660  11.876  8.656   1.00 43.69  ? 52  PHE C N   1 
ATOM   4927  C  CA  . PHE C 1 52  ? 28.903  11.339  9.206   1.00 33.19  ? 52  PHE C CA  1 
ATOM   4928  C  C   . PHE C 1 52  ? 29.060  11.726  10.671  1.00 34.60  ? 52  PHE C C   1 
ATOM   4929  O  O   . PHE C 1 52  ? 29.370  10.846  11.442  1.00 34.50  ? 52  PHE C O   1 
ATOM   4930  C  CB  . PHE C 1 52  ? 30.099  11.815  8.406   1.00 31.97  ? 52  PHE C CB  1 
ATOM   4931  C  CG  . PHE C 1 52  ? 31.355  11.253  9.016   1.00 29.32  ? 52  PHE C CG  1 
ATOM   4932  C  CD1 . PHE C 1 52  ? 31.727  9.969   8.694   1.00 27.81  ? 52  PHE C CD1 1 
ATOM   4933  C  CD2 . PHE C 1 52  ? 32.146  11.989  9.896   1.00 30.52  ? 52  PHE C CD2 1 
ATOM   4934  C  CE1 . PHE C 1 52  ? 32.891  9.412   9.223   1.00 31.15  ? 52  PHE C CE1 1 
ATOM   4935  C  CE2 . PHE C 1 52  ? 33.277  11.409  10.457  1.00 34.17  ? 52  PHE C CE2 1 
ATOM   4936  C  CZ  . PHE C 1 52  ? 33.634  10.117  10.142  1.00 31.44  ? 52  PHE C CZ  1 
ATOM   4937  N  N   . ARG C 1 53  ? 28.764  12.967  11.073  1.00 35.79  ? 53  ARG C N   1 
ATOM   4938  C  CA  . ARG C 1 53  ? 28.910  13.368  12.462  1.00 31.51  ? 53  ARG C CA  1 
ATOM   4939  C  C   . ARG C 1 53  ? 28.008  12.574  13.406  1.00 39.00  ? 53  ARG C C   1 
ATOM   4940  O  O   . ARG C 1 53  ? 28.173  12.690  14.608  1.00 38.40  ? 53  ARG C O   1 
ATOM   4941  C  CB  . ARG C 1 53  ? 28.672  14.861  12.750  1.00 36.91  ? 53  ARG C CB  1 
ATOM   4942  C  CG  . ARG C 1 53  ? 27.354  15.544  12.431  1.00 38.62  ? 53  ARG C CG  1 
ATOM   4943  C  CD  . ARG C 1 53  ? 27.183  16.964  13.019  1.00 46.80  ? 53  ARG C CD  1 
ATOM   4944  N  NE  . ARG C 1 53  ? 26.292  17.808  12.202  1.00 48.99  ? 53  ARG C NE  1 
ATOM   4945  C  CZ  . ARG C 1 53  ? 26.463  17.901  10.873  1.00 55.66  ? 53  ARG C CZ  1 
ATOM   4946  N  NH1 . ARG C 1 53  ? 27.551  17.369  10.348  1.00 65.39  ? 53  ARG C NH1 1 
ATOM   4947  N  NH2 . ARG C 1 53  ? 25.588  18.474  10.057  1.00 51.58  ? 53  ARG C NH2 1 
ATOM   4948  N  N   . ALA C 1 54  ? 27.033  11.795  12.914  1.00 39.00  ? 54  ALA C N   1 
ATOM   4949  C  CA  . ALA C 1 54  ? 26.148  11.046  13.804  1.00 36.50  ? 54  ALA C CA  1 
ATOM   4950  C  C   . ALA C 1 54  ? 26.387  9.563   13.659  1.00 34.89  ? 54  ALA C C   1 
ATOM   4951  O  O   . ALA C 1 54  ? 25.594  8.786   14.144  1.00 42.14  ? 54  ALA C O   1 
ATOM   4952  C  CB  . ALA C 1 54  ? 24.690  11.367  13.560  1.00 37.55  ? 54  ALA C CB  1 
ATOM   4953  N  N   . GLN C 1 55  ? 27.484  9.171   13.024  1.00 39.88  ? 55  GLN C N   1 
ATOM   4954  C  CA  . GLN C 1 55  ? 27.871  7.767   12.932  1.00 50.45  ? 55  GLN C CA  1 
ATOM   4955  C  C   . GLN C 1 55  ? 28.278  7.238   14.304  1.00 55.28  ? 55  GLN C C   1 
ATOM   4956  O  O   . GLN C 1 55  ? 28.716  8.013   15.139  1.00 55.41  ? 55  GLN C O   1 
ATOM   4957  C  CB  . GLN C 1 55  ? 29.039  7.511   11.971  1.00 59.85  ? 55  GLN C CB  1 
ATOM   4958  C  CG  . GLN C 1 55  ? 28.679  7.702   10.495  1.00 53.88  ? 55  GLN C CG  1 
ATOM   4959  C  CD  . GLN C 1 55  ? 27.637  6.734   9.959   1.00 64.36  ? 55  GLN C CD  1 
ATOM   4960  O  OE1 . GLN C 1 55  ? 26.570  6.428   10.539  1.00 69.23  ? 55  GLN C OE1 1 
ATOM   4961  N  NE2 . GLN C 1 55  ? 27.947  6.257   8.764   1.00 66.80  ? 55  GLN C NE2 1 
ATOM   4962  N  N   . PRO C 1 56  ? 28.092  5.921   14.568  1.00 68.25  ? 56  PRO C N   1 
ATOM   4963  C  CA  . PRO C 1 56  ? 27.486  5.002   13.584  1.00 72.04  ? 56  PRO C CA  1 
ATOM   4964  C  C   . PRO C 1 56  ? 25.972  4.712   13.738  1.00 62.88  ? 56  PRO C C   1 
ATOM   4965  O  O   . PRO C 1 56  ? 25.341  4.152   12.830  1.00 55.99  ? 56  PRO C O   1 
ATOM   4966  C  CB  . PRO C 1 56  ? 28.415  3.754   13.781  1.00 63.24  ? 56  PRO C CB  1 
ATOM   4967  C  CG  . PRO C 1 56  ? 28.952  3.874   15.218  1.00 58.17  ? 56  PRO C CG  1 
ATOM   4968  C  CD  . PRO C 1 56  ? 28.471  5.220   15.805  1.00 60.70  ? 56  PRO C CD  1 
ATOM   4969  N  N   . ASP C 1 57  ? 25.386  5.195   14.850  1.00 62.57  ? 57  ASP C N   1 
ATOM   4970  C  CA  . ASP C 1 57  ? 23.975  5.084   15.210  1.00 62.49  ? 57  ASP C CA  1 
ATOM   4971  C  C   . ASP C 1 57  ? 22.997  5.731   14.241  1.00 56.87  ? 57  ASP C C   1 
ATOM   4972  O  O   . ASP C 1 57  ? 21.832  5.365   14.261  1.00 55.00  ? 57  ASP C O   1 
ATOM   4973  C  CB  . ASP C 1 57  ? 23.671  5.950   16.422  1.00 76.69  ? 57  ASP C CB  1 
ATOM   4974  C  CG  . ASP C 1 57  ? 24.818  5.844   17.399  1.00 96.38  ? 57  ASP C CG  1 
ATOM   4975  O  OD1 . ASP C 1 57  ? 25.213  4.649   17.592  1.00 80.84  ? 57  ASP C OD1 1 
ATOM   4976  O  OD2 . ASP C 1 57  ? 25.356  6.925   17.790  1.00 94.26  ? 57  ASP C OD2 1 
ATOM   4977  N  N   . GLY C 1 58  ? 23.424  6.783   13.520  1.00 54.18  ? 58  GLY C N   1 
ATOM   4978  C  CA  . GLY C 1 58  ? 22.509  7.595   12.713  1.00 45.54  ? 58  GLY C CA  1 
ATOM   4979  C  C   . GLY C 1 58  ? 21.852  6.829   11.553  1.00 37.99  ? 58  GLY C C   1 
ATOM   4980  O  O   . GLY C 1 58  ? 20.658  6.981   11.324  1.00 30.66  ? 58  GLY C O   1 
ATOM   4981  N  N   . ARG C 1 59  ? 22.659  6.041   10.822  1.00 33.97  ? 59  ARG C N   1 
ATOM   4982  C  CA  . ARG C 1 59  ? 22.187  5.165   9.774   1.00 33.44  ? 59  ARG C CA  1 
ATOM   4983  C  C   . ARG C 1 59  ? 21.430  5.949   8.710   1.00 32.99  ? 59  ARG C C   1 
ATOM   4984  O  O   . ARG C 1 59  ? 20.492  5.452   8.134   1.00 36.01  ? 59  ARG C O   1 
ATOM   4985  C  CB  . ARG C 1 59  ? 21.341  4.053   10.386  1.00 37.77  ? 59  ARG C CB  1 
ATOM   4986  C  CG  . ARG C 1 59  ? 22.197  3.034   11.137  1.00 57.03  ? 59  ARG C CG  1 
ATOM   4987  C  CD  . ARG C 1 59  ? 21.691  1.603   10.927  1.00 71.51  ? 59  ARG C CD  1 
ATOM   4988  N  NE  . ARG C 1 59  ? 21.340  0.773   12.083  1.00 82.21  ? 59  ARG C NE  1 
ATOM   4989  C  CZ  . ARG C 1 59  ? 20.437  1.056   13.037  1.00 97.58  ? 59  ARG C CZ  1 
ATOM   4990  N  NH1 . ARG C 1 59  ? 20.230  2.290   13.492  1.00 68.10  ? 59  ARG C NH1 1 
ATOM   4991  N  NH2 . ARG C 1 59  ? 19.806  0.043   13.621  1.00 117.69 ? 59  ARG C NH2 1 
ATOM   4992  N  N   . LEU C 1 60  ? 21.867  7.169   8.426   1.00 28.90  ? 60  LEU C N   1 
ATOM   4993  C  CA  . LEU C 1 60  ? 21.199  8.015   7.459   1.00 26.02  ? 60  LEU C CA  1 
ATOM   4994  C  C   . LEU C 1 60  ? 21.532  7.552   6.060   1.00 28.09  ? 60  LEU C C   1 
ATOM   4995  O  O   . LEU C 1 60  ? 22.691  7.366   5.781   1.00 29.20  ? 60  LEU C O   1 
ATOM   4996  C  CB  . LEU C 1 60  ? 21.727  9.430   7.600   1.00 24.48  ? 60  LEU C CB  1 
ATOM   4997  C  CG  . LEU C 1 60  ? 21.166  10.467  6.629   1.00 24.54  ? 60  LEU C CG  1 
ATOM   4998  C  CD1 . LEU C 1 60  ? 19.680  10.717  6.873   1.00 23.82  ? 60  LEU C CD1 1 
ATOM   4999  C  CD2 . LEU C 1 60  ? 21.829  11.815  6.827   1.00 26.75  ? 60  LEU C CD2 1 
ATOM   5000  N  N   . SER C 1 61  ? 20.531  7.421   5.183   1.00 29.51  ? 61  SER C N   1 
ATOM   5001  C  CA  . SER C 1 61  ? 20.715  7.146   3.761   1.00 25.03  ? 61  SER C CA  1 
ATOM   5002  C  C   . SER C 1 61  ? 19.647  7.880   3.002   1.00 22.97  ? 61  SER C C   1 
ATOM   5003  O  O   . SER C 1 61  ? 18.599  8.176   3.529   1.00 24.01  ? 61  SER C O   1 
ATOM   5004  C  CB  . SER C 1 61  ? 20.666  5.689   3.400   1.00 24.31  ? 61  SER C CB  1 
ATOM   5005  O  OG  . SER C 1 61  ? 19.485  5.016   3.767   1.00 26.53  ? 61  SER C OG  1 
ATOM   5006  N  N   . CYS C 1 62  ? 19.979  8.199   1.771   1.00 23.04  ? 62  CYS C N   1 
ATOM   5007  C  CA  . CYS C 1 62  ? 19.046  8.795   0.847   1.00 20.52  ? 62  CYS C CA  1 
ATOM   5008  C  C   . CYS C 1 62  ? 19.036  7.961   -0.425  1.00 20.26  ? 62  CYS C C   1 
ATOM   5009  O  O   . CYS C 1 62  ? 20.066  7.716   -0.951  1.00 26.18  ? 62  CYS C O   1 
ATOM   5010  C  CB  . CYS C 1 62  ? 19.449  10.223  0.548   1.00 21.00  ? 62  CYS C CB  1 
ATOM   5011  S  SG  . CYS C 1 62  ? 18.322  10.873  -0.701  1.00 25.43  ? 62  CYS C SG  1 
ATOM   5012  N  N   . VAL C 1 63  ? 17.932  7.391   -0.853  1.00 23.99  ? 63  VAL C N   1 
ATOM   5013  C  CA  . VAL C 1 63  ? 17.874  6.793   -2.192  1.00 25.42  ? 63  VAL C CA  1 
ATOM   5014  C  C   . VAL C 1 63  ? 17.146  7.751   -3.139  1.00 25.36  ? 63  VAL C C   1 
ATOM   5015  O  O   . VAL C 1 63  ? 16.047  8.234   -2.801  1.00 24.11  ? 63  VAL C O   1 
ATOM   5016  C  CB  . VAL C 1 63  ? 17.170  5.423   -2.158  1.00 25.08  ? 63  VAL C CB  1 
ATOM   5017  C  CG1 . VAL C 1 63  ? 16.931  4.858   -3.555  1.00 22.34  ? 63  VAL C CG1 1 
ATOM   5018  C  CG2 . VAL C 1 63  ? 17.934  4.476   -1.257  1.00 27.24  ? 63  VAL C CG2 1 
ATOM   5019  N  N   . THR C 1 64  ? 17.794  8.077   -4.261  1.00 23.27  ? 64  THR C N   1 
ATOM   5020  C  CA  . THR C 1 64  ? 17.226  8.992   -5.228  1.00 21.47  ? 64  THR C CA  1 
ATOM   5021  C  C   . THR C 1 64  ? 16.705  8.215   -6.425  1.00 21.05  ? 64  THR C C   1 
ATOM   5022  O  O   . THR C 1 64  ? 17.411  7.431   -7.008  1.00 23.61  ? 64  THR C O   1 
ATOM   5023  C  CB  . THR C 1 64  ? 18.313  9.920   -5.696  1.00 21.40  ? 64  THR C CB  1 
ATOM   5024  O  OG1 . THR C 1 64  ? 18.868  10.513  -4.544  1.00 24.64  ? 64  THR C OG1 1 
ATOM   5025  C  CG2 . THR C 1 64  ? 17.778  10.978  -6.632  1.00 25.23  ? 64  THR C CG2 1 
ATOM   5026  N  N   . GLY C 1 65  ? 15.503  8.526   -6.834  1.00 20.71  ? 65  GLY C N   1 
ATOM   5027  C  CA  . GLY C 1 65  ? 14.808  7.902   -7.947  1.00 23.12  ? 65  GLY C CA  1 
ATOM   5028  C  C   . GLY C 1 65  ? 14.313  8.939   -8.980  1.00 23.40  ? 65  GLY C C   1 
ATOM   5029  O  O   . GLY C 1 65  ? 13.942  10.071  -8.651  1.00 21.76  ? 65  GLY C O   1 
ATOM   5030  N  N   . ILE C 1 66  ? 14.346  8.535   -10.256 1.00 22.24  ? 66  ILE C N   1 
ATOM   5031  C  CA  . ILE C 1 66  ? 13.975  9.390   -11.350 1.00 23.94  ? 66  ILE C CA  1 
ATOM   5032  C  C   . ILE C 1 66  ? 12.862  8.706   -12.128 1.00 23.32  ? 66  ILE C C   1 
ATOM   5033  O  O   . ILE C 1 66  ? 12.910  7.516   -12.405 1.00 22.34  ? 66  ILE C O   1 
ATOM   5034  C  CB  . ILE C 1 66  ? 15.223  9.676   -12.189 1.00 27.79  ? 66  ILE C CB  1 
ATOM   5035  C  CG1 . ILE C 1 66  ? 16.286  10.318  -11.324 1.00 34.25  ? 66  ILE C CG1 1 
ATOM   5036  C  CG2 . ILE C 1 66  ? 14.900  10.583  -13.386 1.00 28.10  ? 66  ILE C CG2 1 
ATOM   5037  C  CD1 . ILE C 1 66  ? 17.679  9.980   -11.758 1.00 36.24  ? 66  ILE C CD1 1 
ATOM   5038  N  N   . GLY C 1 67  ? 11.824  9.465   -12.437 1.00 23.49  ? 67  GLY C N   1 
ATOM   5039  C  CA  . GLY C 1 67  ? 10.729  8.914   -13.229 1.00 27.56  ? 67  GLY C CA  1 
ATOM   5040  C  C   . GLY C 1 67  ? 11.014  8.856   -14.740 1.00 27.31  ? 67  GLY C C   1 
ATOM   5041  O  O   . GLY C 1 67  ? 12.024  9.355   -15.248 1.00 24.77  ? 67  GLY C O   1 
ATOM   5042  N  N   . SER C 1 68  ? 10.072  8.217   -15.416 1.00 26.88  ? 68  SER C N   1 
ATOM   5043  C  CA  . SER C 1 68  ? 10.134  7.978   -16.854 1.00 35.71  ? 68  SER C CA  1 
ATOM   5044  C  C   . SER C 1 68  ? 10.215  9.261   -17.700 1.00 28.14  ? 68  SER C C   1 
ATOM   5045  O  O   . SER C 1 68  ? 11.145  9.431   -18.465 1.00 26.18  ? 68  SER C O   1 
ATOM   5046  C  CB  . SER C 1 68  ? 8.950   7.141   -17.259 1.00 36.54  ? 68  SER C CB  1 
ATOM   5047  O  OG  . SER C 1 68  ? 9.181   6.636   -18.560 1.00 36.96  ? 68  SER C OG  1 
ATOM   5048  N  N   . GLU C 1 69  ? 9.293   10.198  -17.509 1.00 26.29  ? 69  GLU C N   1 
ATOM   5049  C  CA  . GLU C 1 69  ? 9.345   11.422  -18.273 1.00 29.91  ? 69  GLU C CA  1 
ATOM   5050  C  C   . GLU C 1 69  ? 10.519  12.293  -17.890 1.00 32.30  ? 69  GLU C C   1 
ATOM   5051  O  O   . GLU C 1 69  ? 11.145  12.929  -18.741 1.00 30.94  ? 69  GLU C O   1 
ATOM   5052  C  CB  . GLU C 1 69  ? 8.069   12.224  -18.145 1.00 36.67  ? 69  GLU C CB  1 
ATOM   5053  C  CG  . GLU C 1 69  ? 6.879   11.426  -18.690 1.00 50.54  ? 69  GLU C CG  1 
ATOM   5054  C  CD  . GLU C 1 69  ? 5.742   12.336  -18.339 1.00 68.42  ? 69  GLU C CD  1 
ATOM   5055  O  OE1 . GLU C 1 69  ? 5.930   13.599  -18.355 1.00 63.92  ? 69  GLU C OE1 1 
ATOM   5056  O  OE2 . GLU C 1 69  ? 4.726   11.732  -17.973 1.00 80.32  ? 69  GLU C OE2 1 
ATOM   5057  N  N   . ALA C 1 70  ? 10.827  12.337  -16.601 1.00 30.90  ? 70  ALA C N   1 
ATOM   5058  C  CA  . ALA C 1 70  ? 11.975  13.124  -16.186 1.00 32.43  ? 70  ALA C CA  1 
ATOM   5059  C  C   . ALA C 1 70  ? 13.281  12.578  -16.791 1.00 29.57  ? 70  ALA C C   1 
ATOM   5060  O  O   . ALA C 1 70  ? 14.203  13.347  -17.074 1.00 29.51  ? 70  ALA C O   1 
ATOM   5061  C  CB  . ALA C 1 70  ? 12.022  13.122  -14.681 1.00 32.74  ? 70  ALA C CB  1 
ATOM   5062  N  N   . TRP C 1 71  ? 13.387  11.248  -16.923 1.00 23.79  ? 71  TRP C N   1 
ATOM   5063  C  CA  . TRP C 1 71  ? 14.596  10.649  -17.448 1.00 26.05  ? 71  TRP C CA  1 
ATOM   5064  C  C   . TRP C 1 71  ? 14.976  11.217  -18.825 1.00 27.72  ? 71  TRP C C   1 
ATOM   5065  O  O   . TRP C 1 71  ? 16.141  11.546  -19.099 1.00 25.94  ? 71  TRP C O   1 
ATOM   5066  C  CB  . TRP C 1 71  ? 14.421  9.145   -17.544 1.00 26.18  ? 71  TRP C CB  1 
ATOM   5067  C  CG  . TRP C 1 71  ? 15.721  8.491   -17.836 1.00 27.15  ? 71  TRP C CG  1 
ATOM   5068  C  CD1 . TRP C 1 71  ? 16.302  8.386   -19.051 1.00 32.42  ? 71  TRP C CD1 1 
ATOM   5069  C  CD2 . TRP C 1 71  ? 16.643  7.964   -16.869 1.00 31.72  ? 71  TRP C CD2 1 
ATOM   5070  N  NE1 . TRP C 1 71  ? 17.526  7.789   -18.906 1.00 33.19  ? 71  TRP C NE1 1 
ATOM   5071  C  CE2 . TRP C 1 71  ? 17.752  7.506   -17.590 1.00 31.29  ? 71  TRP C CE2 1 
ATOM   5072  C  CE3 . TRP C 1 71  ? 16.617  7.801   -15.474 1.00 37.05  ? 71  TRP C CE3 1 
ATOM   5073  C  CZ2 . TRP C 1 71  ? 18.842  6.919   -16.966 1.00 34.28  ? 71  TRP C CZ2 1 
ATOM   5074  C  CZ3 . TRP C 1 71  ? 17.690  7.208   -14.842 1.00 37.68  ? 71  TRP C CZ3 1 
ATOM   5075  C  CH2 . TRP C 1 71  ? 18.801  6.807   -15.591 1.00 42.29  ? 71  TRP C CH2 1 
ATOM   5076  N  N   . ASP C 1 72  ? 13.951  11.348  -19.660 1.00 31.21  ? 72  ASP C N   1 
ATOM   5077  C  CA  . ASP C 1 72  ? 14.083  11.865  -21.014 1.00 35.19  ? 72  ASP C CA  1 
ATOM   5078  C  C   . ASP C 1 72  ? 14.406  13.344  -20.991 1.00 33.37  ? 72  ASP C C   1 
ATOM   5079  O  O   . ASP C 1 72  ? 15.072  13.776  -21.877 1.00 35.33  ? 72  ASP C O   1 
ATOM   5080  C  CB  . ASP C 1 72  ? 12.855  11.599  -21.870 1.00 37.22  ? 72  ASP C CB  1 
ATOM   5081  C  CG  . ASP C 1 72  ? 12.704  10.118  -22.198 1.00 40.07  ? 72  ASP C CG  1 
ATOM   5082  O  OD1 . ASP C 1 72  ? 13.723  9.385   -22.120 1.00 41.43  ? 72  ASP C OD1 1 
ATOM   5083  O  OD2 . ASP C 1 72  ? 11.562  9.686   -22.457 1.00 45.04  ? 72  ASP C OD2 1 
ATOM   5084  N  N   . ARG C 1 73  ? 13.961  14.124  -19.999 1.00 34.83  ? 73  ARG C N   1 
ATOM   5085  C  CA  . ARG C 1 73  ? 14.383  15.522  -19.934 1.00 31.63  ? 73  ARG C CA  1 
ATOM   5086  C  C   . ARG C 1 73  ? 15.812  15.658  -19.430 1.00 33.31  ? 73  ARG C C   1 
ATOM   5087  O  O   . ARG C 1 73  ? 16.377  16.718  -19.572 1.00 36.66  ? 73  ARG C O   1 
ATOM   5088  C  CB  . ARG C 1 73  ? 13.480  16.340  -19.014 1.00 30.15  ? 73  ARG C CB  1 
ATOM   5089  C  CG  . ARG C 1 73  ? 12.020  16.245  -19.426 1.00 31.84  ? 73  ARG C CG  1 
ATOM   5090  C  CD  . ARG C 1 73  ? 11.037  16.693  -18.377 1.00 34.03  ? 73  ARG C CD  1 
ATOM   5091  N  NE  . ARG C 1 73  ? 11.324  18.087  -18.017 1.00 32.90  ? 73  ARG C NE  1 
ATOM   5092  C  CZ  . ARG C 1 73  ? 10.758  18.669  -16.927 1.00 31.42  ? 73  ARG C CZ  1 
ATOM   5093  N  NH1 . ARG C 1 73  ? 9.866   18.000  -16.174 1.00 29.80  ? 73  ARG C NH1 1 
ATOM   5094  N  NH2 . ARG C 1 73  ? 11.010  19.942  -16.650 1.00 27.06  ? 73  ARG C NH2 1 
ATOM   5095  N  N   . LEU C 1 74  ? 16.344  14.686  -18.677 1.00 37.34  ? 74  LEU C N   1 
ATOM   5096  C  CA  . LEU C 1 74  ? 17.548  14.944  -17.908 1.00 44.23  ? 74  LEU C CA  1 
ATOM   5097  C  C   . LEU C 1 74  ? 18.781  14.423  -18.625 1.00 43.65  ? 74  LEU C C   1 
ATOM   5098  O  O   . LEU C 1 74  ? 19.859  14.939  -18.416 1.00 37.98  ? 74  LEU C O   1 
ATOM   5099  C  CB  . LEU C 1 74  ? 17.476  14.317  -16.511 1.00 46.06  ? 74  LEU C CB  1 
ATOM   5100  C  CG  . LEU C 1 74  ? 16.625  15.059  -15.478 1.00 47.37  ? 74  LEU C CG  1 
ATOM   5101  C  CD1 . LEU C 1 74  ? 16.618  14.259  -14.194 1.00 48.01  ? 74  LEU C CD1 1 
ATOM   5102  C  CD2 . LEU C 1 74  ? 17.198  16.415  -15.179 1.00 45.06  ? 74  LEU C CD2 1 
ATOM   5103  N  N   . PHE C 1 75  ? 18.623  13.298  -19.314 1.00 42.52  ? 75  PHE C N   1 
ATOM   5104  C  CA  . PHE C 1 75  ? 19.724  12.502  -19.820 1.00 40.41  ? 75  PHE C CA  1 
ATOM   5105  C  C   . PHE C 1 75  ? 19.439  12.138  -21.269 1.00 47.74  ? 75  PHE C C   1 
ATOM   5106  O  O   . PHE C 1 75  ? 18.276  11.964  -21.652 1.00 47.73  ? 75  PHE C O   1 
ATOM   5107  C  CB  . PHE C 1 75  ? 19.755  11.162  -19.085 1.00 38.63  ? 75  PHE C CB  1 
ATOM   5108  C  CG  . PHE C 1 75  ? 19.810  11.312  -17.589 1.00 38.47  ? 75  PHE C CG  1 
ATOM   5109  C  CD1 . PHE C 1 75  ? 20.810  12.068  -17.001 1.00 41.54  ? 75  PHE C CD1 1 
ATOM   5110  C  CD2 . PHE C 1 75  ? 18.815  10.777  -16.777 1.00 42.50  ? 75  PHE C CD2 1 
ATOM   5111  C  CE1 . PHE C 1 75  ? 20.874  12.225  -15.620 1.00 40.96  ? 75  PHE C CE1 1 
ATOM   5112  C  CE2 . PHE C 1 75  ? 18.860  10.981  -15.398 1.00 43.96  ? 75  PHE C CE2 1 
ATOM   5113  C  CZ  . PHE C 1 75  ? 19.879  11.699  -14.826 1.00 40.81  ? 75  PHE C CZ  1 
ATOM   5114  N  N   . SER C 1 76  ? 20.449  11.911  -22.103 1.00 58.45  ? 76  SER C N   1 
ATOM   5115  C  CA  . SER C 1 76  ? 20.027  11.154  -23.284 1.00 73.76  ? 76  SER C CA  1 
ATOM   5116  C  C   . SER C 1 76  ? 21.000  10.022  -23.455 1.00 57.28  ? 76  SER C C   1 
ATOM   5117  O  O   . SER C 1 76  ? 21.917  9.875   -22.672 1.00 56.32  ? 76  SER C O   1 
ATOM   5118  C  CB  . SER C 1 76  ? 19.812  11.949  -24.569 1.00 77.89  ? 76  SER C CB  1 
ATOM   5119  O  OG  . SER C 1 76  ? 20.985  12.686  -24.849 1.00 75.58  ? 76  SER C OG  1 
ATOM   5120  N  N   . GLY C 1 77  ? 20.737  9.207   -24.444 1.00 49.63  ? 77  GLY C N   1 
ATOM   5121  C  CA  . GLY C 1 77  ? 21.366  7.917   -24.472 1.00 48.25  ? 77  GLY C CA  1 
ATOM   5122  C  C   . GLY C 1 77  ? 20.383  6.917   -23.892 1.00 40.72  ? 77  GLY C C   1 
ATOM   5123  O  O   . GLY C 1 77  ? 19.194  7.132   -23.950 1.00 44.18  ? 77  GLY C O   1 
ATOM   5124  N  N   . ALA C 1 78  ? 20.922  5.864   -23.298 1.00 43.97  ? 78  ALA C N   1 
ATOM   5125  C  CA  . ALA C 1 78  ? 20.158  4.693   -22.948 1.00 45.01  ? 78  ALA C CA  1 
ATOM   5126  C  C   . ALA C 1 78  ? 19.174  5.072   -21.829 1.00 47.49  ? 78  ALA C C   1 
ATOM   5127  O  O   . ALA C 1 78  ? 19.479  5.892   -20.969 1.00 53.50  ? 78  ALA C O   1 
ATOM   5128  C  CB  . ALA C 1 78  ? 21.133  3.567   -22.562 1.00 46.18  ? 78  ALA C CB  1 
ATOM   5129  N  N   . ARG C 1 79  ? 17.954  4.534   -21.926 1.00 42.04  ? 79  ARG C N   1 
ATOM   5130  C  CA  . ARG C 1 79  ? 17.012  4.434   -20.843 1.00 39.51  ? 79  ARG C CA  1 
ATOM   5131  C  C   . ARG C 1 79  ? 17.096  3.054   -20.197 1.00 40.41  ? 79  ARG C C   1 
ATOM   5132  O  O   . ARG C 1 79  ? 17.300  2.065   -20.865 1.00 43.41  ? 79  ARG C O   1 
ATOM   5133  C  CB  . ARG C 1 79  ? 15.613  4.548   -21.419 1.00 36.29  ? 79  ARG C CB  1 
ATOM   5134  C  CG  . ARG C 1 79  ? 15.337  5.985   -21.790 1.00 36.08  ? 79  ARG C CG  1 
ATOM   5135  C  CD  . ARG C 1 79  ? 13.919  5.985   -22.388 1.00 38.85  ? 79  ARG C CD  1 
ATOM   5136  N  NE  . ARG C 1 79  ? 12.944  5.378   -21.483 1.00 35.63  ? 79  ARG C NE  1 
ATOM   5137  C  CZ  . ARG C 1 79  ? 12.195  6.117   -20.690 1.00 39.88  ? 79  ARG C CZ  1 
ATOM   5138  N  NH1 . ARG C 1 79  ? 12.279  7.438   -20.690 1.00 41.30  ? 79  ARG C NH1 1 
ATOM   5139  N  NH2 . ARG C 1 79  ? 11.359  5.544   -19.854 1.00 39.30  ? 79  ARG C NH2 1 
ATOM   5140  N  N   . PRO C 1 80  ? 16.898  2.929   -18.878 1.00 38.97  ? 80  PRO C N   1 
ATOM   5141  C  CA  . PRO C 1 80  ? 16.777  1.596   -18.288 1.00 36.28  ? 80  PRO C CA  1 
ATOM   5142  C  C   . PRO C 1 80  ? 15.591  0.893   -18.949 1.00 33.45  ? 80  PRO C C   1 
ATOM   5143  O  O   . PRO C 1 80  ? 14.554  1.513   -19.197 1.00 31.23  ? 80  PRO C O   1 
ATOM   5144  C  CB  . PRO C 1 80  ? 16.569  1.872   -16.810 1.00 36.87  ? 80  PRO C CB  1 
ATOM   5145  C  CG  . PRO C 1 80  ? 16.993  3.344   -16.621 1.00 39.81  ? 80  PRO C CG  1 
ATOM   5146  C  CD  . PRO C 1 80  ? 16.761  4.064   -17.926 1.00 40.16  ? 80  PRO C CD  1 
ATOM   5147  N  N   . ALA C 1 81  ? 15.752  -0.420  -19.159 1.00 34.06  ? 81  ALA C N   1 
ATOM   5148  C  CA  . ALA C 1 81  ? 14.797  -1.247  -19.891 1.00 35.57  ? 81  ALA C CA  1 
ATOM   5149  C  C   . ALA C 1 81  ? 13.367  -1.178  -19.331 1.00 39.76  ? 81  ALA C C   1 
ATOM   5150  O  O   . ALA C 1 81  ? 12.408  -1.165  -20.090 1.00 40.62  ? 81  ALA C O   1 
ATOM   5151  C  CB  . ALA C 1 81  ? 15.298  -2.655  -19.901 1.00 34.77  ? 81  ALA C CB  1 
ATOM   5152  N  N   . GLY C 1 82  ? 13.192  -1.124  -18.012 1.00 36.41  ? 82  GLY C N   1 
ATOM   5153  C  CA  . GLY C 1 82  ? 11.862  -1.250  -17.426 1.00 36.12  ? 82  GLY C CA  1 
ATOM   5154  C  C   . GLY C 1 82  ? 11.165  0.075   -17.115 1.00 30.56  ? 82  GLY C C   1 
ATOM   5155  O  O   . GLY C 1 82  ? 10.072  0.099   -16.592 1.00 31.84  ? 82  GLY C O   1 
ATOM   5156  N  N   . LEU C 1 83  ? 11.785  1.197   -17.404 1.00 34.51  ? 83  LEU C N   1 
ATOM   5157  C  CA  . LEU C 1 83  ? 11.261  2.471   -16.928 1.00 30.96  ? 83  LEU C CA  1 
ATOM   5158  C  C   . LEU C 1 83  ? 10.075  2.939   -17.770 1.00 29.93  ? 83  LEU C C   1 
ATOM   5159  O  O   . LEU C 1 83  ? 10.207  3.177   -18.922 1.00 34.70  ? 83  LEU C O   1 
ATOM   5160  C  CB  . LEU C 1 83  ? 12.404  3.501   -16.896 1.00 32.96  ? 83  LEU C CB  1 
ATOM   5161  C  CG  . LEU C 1 83  ? 12.056  4.864   -16.300 1.00 31.92  ? 83  LEU C CG  1 
ATOM   5162  C  CD1 . LEU C 1 83  ? 11.524  4.742   -14.893 1.00 32.40  ? 83  LEU C CD1 1 
ATOM   5163  C  CD2 . LEU C 1 83  ? 13.221  5.756   -16.339 1.00 30.59  ? 83  LEU C CD2 1 
ATOM   5164  N  N   . HIS C 1 84  ? 8.924   3.185   -17.164 1.00 29.73  ? 84  HIS C N   1 
ATOM   5165  C  CA  . HIS C 1 84  ? 7.761   3.754   -17.814 1.00 26.21  ? 84  HIS C CA  1 
ATOM   5166  C  C   . HIS C 1 84  ? 6.951   4.455   -16.731 1.00 25.59  ? 84  HIS C C   1 
ATOM   5167  O  O   . HIS C 1 84  ? 7.256   4.369   -15.536 1.00 29.08  ? 84  HIS C O   1 
ATOM   5168  C  CB  . HIS C 1 84  ? 6.928   2.658   -18.476 1.00 27.71  ? 84  HIS C CB  1 
ATOM   5169  C  CG  . HIS C 1 84  ? 6.679   1.447   -17.633 1.00 27.92  ? 84  HIS C CG  1 
ATOM   5170  N  ND1 . HIS C 1 84  ? 7.462   0.316   -17.752 1.00 33.07  ? 84  HIS C ND1 1 
ATOM   5171  C  CD2 . HIS C 1 84  ? 5.789   1.177   -16.674 1.00 26.63  ? 84  HIS C CD2 1 
ATOM   5172  C  CE1 . HIS C 1 84  ? 7.050   -0.599  -16.853 1.00 32.98  ? 84  HIS C CE1 1 
ATOM   5173  N  NE2 . HIS C 1 84  ? 6.047   -0.102  -16.181 1.00 30.57  ? 84  HIS C NE2 1 
ATOM   5174  N  N   . PRO C 1 85  ? 5.901   5.195   -17.098 1.00 25.03  ? 85  PRO C N   1 
ATOM   5175  C  CA  . PRO C 1 85  ? 5.026   5.815   -16.106 1.00 26.83  ? 85  PRO C CA  1 
ATOM   5176  C  C   . PRO C 1 85  ? 4.279   4.728   -15.362 1.00 30.37  ? 85  PRO C C   1 
ATOM   5177  O  O   . PRO C 1 85  ? 4.025   3.673   -15.914 1.00 32.12  ? 85  PRO C O   1 
ATOM   5178  C  CB  . PRO C 1 85  ? 4.097   6.708   -16.916 1.00 23.06  ? 85  PRO C CB  1 
ATOM   5179  C  CG  . PRO C 1 85  ? 4.917   6.944   -18.194 1.00 21.96  ? 85  PRO C CG  1 
ATOM   5180  C  CD  . PRO C 1 85  ? 5.554   5.594   -18.453 1.00 24.46  ? 85  PRO C CD  1 
ATOM   5181  N  N   . PHE C 1 86  ? 3.985   4.983   -14.103 1.00 27.11  ? 86  PHE C N   1 
ATOM   5182  C  CA  . PHE C 1 86  ? 3.086   4.135   -13.341 1.00 30.39  ? 86  PHE C CA  1 
ATOM   5183  C  C   . PHE C 1 86  ? 1.780   3.931   -14.129 1.00 32.28  ? 86  PHE C C   1 
ATOM   5184  O  O   . PHE C 1 86  ? 1.207   4.901   -14.644 1.00 33.65  ? 86  PHE C O   1 
ATOM   5185  C  CB  . PHE C 1 86  ? 2.794   4.786   -11.980 1.00 26.52  ? 86  PHE C CB  1 
ATOM   5186  C  CG  . PHE C 1 86  ? 1.954   3.940   -11.036 1.00 28.75  ? 86  PHE C CG  1 
ATOM   5187  C  CD1 . PHE C 1 86  ? 2.525   3.022   -10.203 1.00 29.18  ? 86  PHE C CD1 1 
ATOM   5188  C  CD2 . PHE C 1 86  ? 0.575   4.111   -10.969 1.00 30.93  ? 86  PHE C CD2 1 
ATOM   5189  C  CE1 . PHE C 1 86  ? 1.711   2.225   -9.405  1.00 33.73  ? 86  PHE C CE1 1 
ATOM   5190  C  CE2 . PHE C 1 86  ? -0.214  3.309   -10.190 1.00 28.90  ? 86  PHE C CE2 1 
ATOM   5191  C  CZ  . PHE C 1 86  ? 0.343   2.382   -9.415  1.00 32.03  ? 86  PHE C CZ  1 
ATOM   5192  N  N   . ARG C 1 87  ? 1.300   2.678   -14.152 1.00 31.77  ? 87  ARG C N   1 
ATOM   5193  C  CA  . ARG C 1 87  ? 0.099   2.339   -14.896 1.00 36.48  ? 87  ARG C CA  1 
ATOM   5194  C  C   . ARG C 1 87  ? -1.078  2.261   -13.946 1.00 33.64  ? 87  ARG C C   1 
ATOM   5195  O  O   . ARG C 1 87  ? -1.098  1.405   -13.035 1.00 32.86  ? 87  ARG C O   1 
ATOM   5196  C  CB  . ARG C 1 87  ? 0.093   0.986   -15.594 1.00 45.85  ? 87  ARG C CB  1 
ATOM   5197  C  CG  . ARG C 1 87  ? 1.385   0.651   -16.301 1.00 62.55  ? 87  ARG C CG  1 
ATOM   5198  C  CD  . ARG C 1 87  ? 1.495   -0.863  -16.345 1.00 80.81  ? 87  ARG C CD  1 
ATOM   5199  N  NE  . ARG C 1 87  ? 2.007   -1.035  -17.706 1.00 97.92  ? 87  ARG C NE  1 
ATOM   5200  C  CZ  . ARG C 1 87  ? 3.258   -1.264  -18.101 1.00 96.67  ? 87  ARG C CZ  1 
ATOM   5201  N  NH1 . ARG C 1 87  ? 3.660   -0.685  -19.229 1.00 73.87  ? 87  ARG C NH1 1 
ATOM   5202  N  NH2 . ARG C 1 87  ? 4.110   -1.932  -17.327 1.00 109.33 ? 87  ARG C NH2 1 
ATOM   5203  N  N   . GLU C 1 88  ? -2.028  3.181   -14.214 1.00 37.13  ? 88  GLU C N   1 
ATOM   5204  C  CA  . GLU C 1 88  ? -3.286  3.273   -13.507 1.00 37.15  ? 88  GLU C CA  1 
ATOM   5205  C  C   . GLU C 1 88  ? -3.959  1.906   -13.561 1.00 35.55  ? 88  GLU C C   1 
ATOM   5206  O  O   . GLU C 1 88  ? -3.795  1.219   -14.552 1.00 41.69  ? 88  GLU C O   1 
ATOM   5207  C  CB  . GLU C 1 88  ? -3.935  4.476   -14.169 1.00 41.88  ? 88  GLU C CB  1 
ATOM   5208  C  CG  . GLU C 1 88  ? -5.262  4.779   -13.484 1.00 69.20  ? 88  GLU C CG  1 
ATOM   5209  C  CD  . GLU C 1 88  ? -5.553  6.254   -13.355 1.00 75.57  ? 88  GLU C CD  1 
ATOM   5210  O  OE1 . GLU C 1 88  ? -4.645  7.086   -13.011 1.00 47.80  ? 88  GLU C OE1 1 
ATOM   5211  O  OE2 . GLU C 1 88  ? -6.772  6.484   -13.561 1.00 81.51  ? 88  GLU C OE2 1 
ATOM   5212  N  N   . LEU C 1 89  ? -4.577  1.444   -12.468 1.00 37.75  ? 89  LEU C N   1 
ATOM   5213  C  CA  . LEU C 1 89  ? -5.347  0.191   -12.457 1.00 35.91  ? 89  LEU C CA  1 
ATOM   5214  C  C   . LEU C 1 89  ? -6.802  0.514   -12.103 1.00 36.99  ? 89  LEU C C   1 
ATOM   5215  O  O   . LEU C 1 89  ? -7.071  1.098   -11.060 1.00 34.71  ? 89  LEU C O   1 
ATOM   5216  C  CB  . LEU C 1 89  ? -4.788  -0.906  -11.564 1.00 31.85  ? 89  LEU C CB  1 
ATOM   5217  C  CG  . LEU C 1 89  ? -3.347  -1.344  -11.841 1.00 35.80  ? 89  LEU C CG  1 
ATOM   5218  C  CD1 . LEU C 1 89  ? -2.893  -2.512  -11.017 1.00 33.54  ? 89  LEU C CD1 1 
ATOM   5219  C  CD2 . LEU C 1 89  ? -3.125  -1.828  -13.248 1.00 41.28  ? 89  LEU C CD2 1 
ATOM   5220  N  N   . ASP C 1 90  ? -7.722  0.226   -13.053 1.00 40.65  ? 90  ASP C N   1 
ATOM   5221  C  CA  . ASP C 1 90  ? -9.141  0.531   -12.956 1.00 42.73  ? 90  ASP C CA  1 
ATOM   5222  C  C   . ASP C 1 90  ? -9.848  -0.780  -12.687 1.00 39.27  ? 90  ASP C C   1 
ATOM   5223  O  O   . ASP C 1 90  ? -10.162 -1.538  -13.569 1.00 39.70  ? 90  ASP C O   1 
ATOM   5224  C  CB  . ASP C 1 90  ? -9.673  1.190   -14.211 1.00 49.74  ? 90  ASP C CB  1 
ATOM   5225  C  CG  . ASP C 1 90  ? -10.435 2.429   -13.823 1.00 67.05  ? 90  ASP C CG  1 
ATOM   5226  O  OD1 . ASP C 1 90  ? -11.483 2.252   -13.133 1.00 62.38  ? 90  ASP C OD1 1 
ATOM   5227  O  OD2 . ASP C 1 90  ? -9.840  3.515   -14.027 1.00 75.81  ? 90  ASP C OD2 1 
ATOM   5228  N  N   . GLY C 1 91  ? -9.890  -1.179  -11.445 1.00 40.95  ? 91  GLY C N   1 
ATOM   5229  C  CA  . GLY C 1 91  ? -10.543 -2.423  -11.120 1.00 45.44  ? 91  GLY C CA  1 
ATOM   5230  C  C   . GLY C 1 91  ? -12.055 -2.200  -11.018 1.00 43.50  ? 91  GLY C C   1 
ATOM   5231  O  O   . GLY C 1 91  ? -12.573 -1.069  -10.959 1.00 35.96  ? 91  GLY C O   1 
ATOM   5232  N  N   . PRO C 1 92  ? -12.803 -3.317  -10.944 1.00 43.14  ? 92  PRO C N   1 
ATOM   5233  C  CA  . PRO C 1 92  ? -14.241 -3.226  -10.757 1.00 40.64  ? 92  PRO C CA  1 
ATOM   5234  C  C   . PRO C 1 92  ? -14.629 -2.376  -9.560  1.00 40.19  ? 92  PRO C C   1 
ATOM   5235  O  O   . PRO C 1 92  ? -15.595 -1.626  -9.612  1.00 41.76  ? 92  PRO C O   1 
ATOM   5236  C  CB  . PRO C 1 92  ? -14.708 -4.653  -10.638 1.00 38.67  ? 92  PRO C CB  1 
ATOM   5237  C  CG  . PRO C 1 92  ? -13.514 -5.534  -10.994 1.00 40.14  ? 92  PRO C CG  1 
ATOM   5238  C  CD  . PRO C 1 92  ? -12.287 -4.694  -11.078 1.00 45.56  ? 92  PRO C CD  1 
ATOM   5239  N  N   . VAL C 1 93  ? -13.873 -2.455  -8.467  1.00 44.27  ? 93  VAL C N   1 
ATOM   5240  C  CA  . VAL C 1 93  ? -14.236 -1.740  -7.225  1.00 44.19  ? 93  VAL C CA  1 
ATOM   5241  C  C   . VAL C 1 93  ? -13.199 -0.661  -6.863  1.00 35.33  ? 93  VAL C C   1 
ATOM   5242  O  O   . VAL C 1 93  ? -13.533 0.432   -6.446  1.00 30.94  ? 93  VAL C O   1 
ATOM   5243  C  CB  . VAL C 1 93  ? -14.410 -2.768  -6.069  1.00 42.62  ? 93  VAL C CB  1 
ATOM   5244  C  CG1 . VAL C 1 93  ? -14.673 -2.088  -4.737  1.00 39.41  ? 93  VAL C CG1 1 
ATOM   5245  C  CG2 . VAL C 1 93  ? -15.492 -3.785  -6.362  1.00 41.83  ? 93  VAL C CG2 1 
ATOM   5246  N  N   . HIS C 1 94  ? -11.926 -1.058  -6.929  1.00 35.35  ? 94  HIS C N   1 
ATOM   5247  C  CA  . HIS C 1 94  ? -10.811 -0.303  -6.389  1.00 31.77  ? 94  HIS C CA  1 
ATOM   5248  C  C   . HIS C 1 94  ? -9.867  0.092   -7.529  1.00 29.98  ? 94  HIS C C   1 
ATOM   5249  O  O   . HIS C 1 94  ? -9.609  -0.703  -8.453  1.00 30.00  ? 94  HIS C O   1 
ATOM   5250  C  CB  . HIS C 1 94  ? -10.067 -1.173  -5.371  1.00 25.73  ? 94  HIS C CB  1 
ATOM   5251  C  CG  . HIS C 1 94  ? -10.812 -1.494  -4.150  1.00 23.87  ? 94  HIS C CG  1 
ATOM   5252  N  ND1 . HIS C 1 94  ? -11.271 -0.547  -3.218  1.00 24.29  ? 94  HIS C ND1 1 
ATOM   5253  C  CD2 . HIS C 1 94  ? -11.140 -2.761  -3.743  1.00 23.92  ? 94  HIS C CD2 1 
ATOM   5254  C  CE1 . HIS C 1 94  ? -11.908 -1.229  -2.254  1.00 24.84  ? 94  HIS C CE1 1 
ATOM   5255  N  NE2 . HIS C 1 94  ? -11.841 -2.584  -2.553  1.00 28.20  ? 94  HIS C NE2 1 
ATOM   5256  N  N   . ARG C 1 95  ? -9.284  1.285   -7.349  1.00 32.37  ? 95  ARG C N   1 
ATOM   5257  C  CA  . ARG C 1 95  ? -8.523  1.981   -8.356  1.00 37.61  ? 95  ARG C CA  1 
ATOM   5258  C  C   . ARG C 1 95  ? -7.159  2.336   -7.771  1.00 32.58  ? 95  ARG C C   1 
ATOM   5259  O  O   . ARG C 1 95  ? -7.077  2.937   -6.711  1.00 30.11  ? 95  ARG C O   1 
ATOM   5260  C  CB  . ARG C 1 95  ? -9.462  3.153   -8.607  1.00 46.93  ? 95  ARG C CB  1 
ATOM   5261  C  CG  . ARG C 1 95  ? -9.078  4.153   -9.667  1.00 66.04  ? 95  ARG C CG  1 
ATOM   5262  C  CD  . ARG C 1 95  ? -10.356 4.392   -10.476 1.00 89.86  ? 95  ARG C CD  1 
ATOM   5263  N  NE  . ARG C 1 95  ? -9.864  5.368   -11.443 1.00 104.78 ? 95  ARG C NE  1 
ATOM   5264  C  CZ  . ARG C 1 95  ? -9.287  6.491   -11.045 1.00 92.22  ? 95  ARG C CZ  1 
ATOM   5265  N  NH1 . ARG C 1 95  ? -9.542  7.000   -9.840  1.00 77.75  ? 95  ARG C NH1 1 
ATOM   5266  N  NH2 . ARG C 1 95  ? -8.494  7.119   -11.894 1.00 94.44  ? 95  ARG C NH2 1 
ATOM   5267  N  N   . ALA C 1 96  ? -6.106  1.978   -8.505  1.00 31.18  ? 96  ALA C N   1 
ATOM   5268  C  CA  . ALA C 1 96  ? -4.757  2.460   -8.296  1.00 30.17  ? 96  ALA C CA  1 
ATOM   5269  C  C   . ALA C 1 96  ? -4.473  3.642   -9.232  1.00 28.10  ? 96  ALA C C   1 
ATOM   5270  O  O   . ALA C 1 96  ? -4.234  3.463   -10.403 1.00 28.31  ? 96  ALA C O   1 
ATOM   5271  C  CB  . ALA C 1 96  ? -3.776  1.310   -8.512  1.00 28.18  ? 96  ALA C CB  1 
ATOM   5272  N  N   . VAL C 1 97  ? -4.449  4.849   -8.690  1.00 30.08  ? 97  VAL C N   1 
ATOM   5273  C  CA  . VAL C 1 97  ? -4.214  6.068   -9.431  1.00 30.96  ? 97  VAL C CA  1 
ATOM   5274  C  C   . VAL C 1 97  ? -2.735  6.248   -9.703  1.00 29.78  ? 97  VAL C C   1 
ATOM   5275  O  O   . VAL C 1 97  ? -1.877  5.747   -8.971  1.00 28.61  ? 97  VAL C O   1 
ATOM   5276  C  CB  . VAL C 1 97  ? -4.734  7.269   -8.618  1.00 39.49  ? 97  VAL C CB  1 
ATOM   5277  C  CG1 . VAL C 1 97  ? -6.227  7.158   -8.344  1.00 43.68  ? 97  VAL C CG1 1 
ATOM   5278  C  CG2 . VAL C 1 97  ? -4.009  7.476   -7.290  1.00 41.46  ? 97  VAL C CG2 1 
ATOM   5279  N  N   . ALA C 1 98  ? -2.455  7.011   -10.772 1.00 28.67  ? 98  ALA C N   1 
ATOM   5280  C  CA  . ALA C 1 98  ? -1.107  7.439   -11.073 1.00 24.26  ? 98  ALA C CA  1 
ATOM   5281  C  C   . ALA C 1 98  ? -1.064  8.911   -10.818 1.00 26.68  ? 98  ALA C C   1 
ATOM   5282  O  O   . ALA C 1 98  ? -1.847  9.598   -11.403 1.00 31.15  ? 98  ALA C O   1 
ATOM   5283  C  CB  . ALA C 1 98  ? -0.719  7.185   -12.474 1.00 24.53  ? 98  ALA C CB  1 
ATOM   5284  N  N   . THR C 1 99  ? -0.118  9.391   -10.023 1.00 27.46  ? 99  THR C N   1 
ATOM   5285  C  CA  . THR C 1 99  ? 0.011   10.811  -9.758  1.00 23.80  ? 99  THR C CA  1 
ATOM   5286  C  C   . THR C 1 99  ? 1.383   11.269  -10.179 1.00 23.19  ? 99  THR C C   1 
ATOM   5287  O  O   . THR C 1 99  ? 2.255   10.462  -10.408 1.00 22.45  ? 99  THR C O   1 
ATOM   5288  C  CB  . THR C 1 99  ? -0.247  11.101  -8.289  1.00 24.95  ? 99  THR C CB  1 
ATOM   5289  O  OG1 . THR C 1 99  ? 0.581   10.237  -7.506  1.00 26.18  ? 99  THR C OG1 1 
ATOM   5290  C  CG2 . THR C 1 99  ? -1.698  10.866  -7.969  1.00 22.91  ? 99  THR C CG2 1 
ATOM   5291  N  N   . PRO C 1 100 ? 1.573   12.579  -10.381 1.00 25.31  ? 100 PRO C N   1 
ATOM   5292  C  CA  . PRO C 1 100 ? 2.822   13.118  -10.935 1.00 23.93  ? 100 PRO C CA  1 
ATOM   5293  C  C   . PRO C 1 100 ? 3.977   13.003  -9.967  1.00 23.15  ? 100 PRO C C   1 
ATOM   5294  O  O   . PRO C 1 100 ? 3.791   13.225  -8.766  1.00 26.57  ? 100 PRO C O   1 
ATOM   5295  C  CB  . PRO C 1 100 ? 2.529   14.598  -11.161 1.00 25.74  ? 100 PRO C CB  1 
ATOM   5296  C  CG  . PRO C 1 100 ? 1.056   14.640  -11.136 1.00 26.58  ? 100 PRO C CG  1 
ATOM   5297  C  CD  . PRO C 1 100 ? 0.558   13.595  -10.148 1.00 24.92  ? 100 PRO C CD  1 
ATOM   5298  N  N   . GLY C 1 101 ? 5.148   12.793  -10.534 1.00 21.98  ? 101 GLY C N   1 
ATOM   5299  C  CA  . GLY C 1 101 ? 6.354   12.523  -9.778  1.00 23.74  ? 101 GLY C CA  1 
ATOM   5300  C  C   . GLY C 1 101 ? 7.580   12.402  -10.669 1.00 22.52  ? 101 GLY C C   1 
ATOM   5301  O  O   . GLY C 1 101 ? 7.712   11.419  -11.369 1.00 27.95  ? 101 GLY C O   1 
ATOM   5302  N  N   . ASP C 1 102 ? 8.517   13.336  -10.583 1.00 21.43  ? 102 ASP C N   1 
ATOM   5303  C  CA  . ASP C 1 102 ? 9.723   13.240  -11.379 1.00 26.27  ? 102 ASP C CA  1 
ATOM   5304  C  C   . ASP C 1 102 ? 10.903  12.715  -10.585 1.00 23.28  ? 102 ASP C C   1 
ATOM   5305  O  O   . ASP C 1 102 ? 11.714  11.999  -11.123 1.00 24.71  ? 102 ASP C O   1 
ATOM   5306  C  CB  . ASP C 1 102 ? 10.040  14.590  -11.999 1.00 29.04  ? 102 ASP C CB  1 
ATOM   5307  C  CG  . ASP C 1 102 ? 9.003   15.031  -13.039 1.00 27.71  ? 102 ASP C CG  1 
ATOM   5308  O  OD1 . ASP C 1 102 ? 8.345   14.139  -13.680 1.00 23.44  ? 102 ASP C OD1 1 
ATOM   5309  O  OD2 . ASP C 1 102 ? 8.842   16.263  -13.169 1.00 27.97  ? 102 ASP C OD2 1 
ATOM   5310  N  N   . LEU C 1 103 ? 10.997  13.103  -9.313  1.00 25.21  ? 103 LEU C N   1 
ATOM   5311  C  CA  . LEU C 1 103 ? 12.116  12.750  -8.445  1.00 22.65  ? 103 LEU C CA  1 
ATOM   5312  C  C   . LEU C 1 103 ? 11.549  12.202  -7.154  1.00 19.99  ? 103 LEU C C   1 
ATOM   5313  O  O   . LEU C 1 103 ? 10.582  12.793  -6.664  1.00 20.88  ? 103 LEU C O   1 
ATOM   5314  C  CB  . LEU C 1 103 ? 12.971  13.954  -8.123  1.00 22.67  ? 103 LEU C CB  1 
ATOM   5315  C  CG  . LEU C 1 103 ? 13.785  14.562  -9.262  1.00 26.31  ? 103 LEU C CG  1 
ATOM   5316  C  CD1 . LEU C 1 103 ? 14.571  15.778  -8.751  1.00 24.66  ? 103 LEU C CD1 1 
ATOM   5317  C  CD2 . LEU C 1 103 ? 14.743  13.551  -9.819  1.00 28.46  ? 103 LEU C CD2 1 
ATOM   5318  N  N   . LEU C 1 104 ? 12.160  11.123  -6.646  1.00 17.44  ? 104 LEU C N   1 
ATOM   5319  C  CA  . LEU C 1 104 ? 11.913  10.605  -5.319  1.00 17.56  ? 104 LEU C CA  1 
ATOM   5320  C  C   . LEU C 1 104 ? 13.159  10.730  -4.474  1.00 20.61  ? 104 LEU C C   1 
ATOM   5321  O  O   . LEU C 1 104 ? 14.233  10.324  -4.920  1.00 20.46  ? 104 LEU C O   1 
ATOM   5322  C  CB  . LEU C 1 104 ? 11.542  9.129   -5.402  1.00 21.12  ? 104 LEU C CB  1 
ATOM   5323  C  CG  . LEU C 1 104 ? 11.483  8.319   -4.097  1.00 19.61  ? 104 LEU C CG  1 
ATOM   5324  C  CD1 . LEU C 1 104 ? 10.306  8.700   -3.289  1.00 19.51  ? 104 LEU C CD1 1 
ATOM   5325  C  CD2 . LEU C 1 104 ? 11.313  6.876   -4.330  1.00 21.25  ? 104 LEU C CD2 1 
ATOM   5326  N  N   . PHE C 1 105 ? 12.991  11.240  -3.227  1.00 21.70  ? 105 PHE C N   1 
ATOM   5327  C  CA  . PHE C 1 105 ? 14.029  11.133  -2.227  1.00 22.18  ? 105 PHE C CA  1 
ATOM   5328  C  C   . PHE C 1 105 ? 13.463  10.294  -1.096  1.00 20.88  ? 105 PHE C C   1 
ATOM   5329  O  O   . PHE C 1 105 ? 12.483  10.694  -0.507  1.00 20.09  ? 105 PHE C O   1 
ATOM   5330  C  CB  . PHE C 1 105 ? 14.555  12.497  -1.785  1.00 21.51  ? 105 PHE C CB  1 
ATOM   5331  C  CG  . PHE C 1 105 ? 15.075  13.339  -2.921  1.00 20.09  ? 105 PHE C CG  1 
ATOM   5332  C  CD1 . PHE C 1 105 ? 16.339  13.128  -3.420  1.00 21.62  ? 105 PHE C CD1 1 
ATOM   5333  C  CD2 . PHE C 1 105 ? 14.301  14.312  -3.491  1.00 20.59  ? 105 PHE C CD2 1 
ATOM   5334  C  CE1 . PHE C 1 105 ? 16.839  13.873  -4.467  1.00 21.72  ? 105 PHE C CE1 1 
ATOM   5335  C  CE2 . PHE C 1 105 ? 14.809  15.075  -4.507  1.00 22.89  ? 105 PHE C CE2 1 
ATOM   5336  C  CZ  . PHE C 1 105 ? 16.065  14.839  -5.004  1.00 21.74  ? 105 PHE C CZ  1 
ATOM   5337  N  N   . HIS C 1 106 ? 13.997  9.074   -0.927  1.00 19.83  ? 106 HIS C N   1 
ATOM   5338  C  CA  . HIS C 1 106 ? 13.587  8.176   0.131   1.00 18.39  ? 106 HIS C CA  1 
ATOM   5339  C  C   . HIS C 1 106 ? 14.699  8.195   1.174   1.00 20.12  ? 106 HIS C C   1 
ATOM   5340  O  O   . HIS C 1 106 ? 15.775  7.607   0.966   1.00 21.28  ? 106 HIS C O   1 
ATOM   5341  C  CB  . HIS C 1 106 ? 13.422  6.760   -0.410  1.00 18.07  ? 106 HIS C CB  1 
ATOM   5342  C  CG  . HIS C 1 106 ? 13.033  5.744   0.613   1.00 16.65  ? 106 HIS C CG  1 
ATOM   5343  N  ND1 . HIS C 1 106 ? 13.233  4.404   0.414   1.00 15.43  ? 106 HIS C ND1 1 
ATOM   5344  C  CD2 . HIS C 1 106 ? 12.493  5.866   1.790   1.00 16.35  ? 106 HIS C CD2 1 
ATOM   5345  C  CE1 . HIS C 1 106 ? 12.763  3.758   1.464   1.00 18.28  ? 106 HIS C CE1 1 
ATOM   5346  N  NE2 . HIS C 1 106 ? 12.331  4.625   2.347   1.00 17.37  ? 106 HIS C NE2 1 
ATOM   5347  N  N   . ILE C 1 107 ? 14.457  8.994   2.221   1.00 22.59  ? 107 ILE C N   1 
ATOM   5348  C  CA  . ILE C 1 107 ? 15.448  9.302   3.232   1.00 19.58  ? 107 ILE C CA  1 
ATOM   5349  C  C   . ILE C 1 107 ? 15.108  8.515   4.495   1.00 21.55  ? 107 ILE C C   1 
ATOM   5350  O  O   . ILE C 1 107 ? 13.972  8.548   4.953   1.00 21.30  ? 107 ILE C O   1 
ATOM   5351  C  CB  . ILE C 1 107 ? 15.491  10.799  3.472   1.00 18.72  ? 107 ILE C CB  1 
ATOM   5352  C  CG1 . ILE C 1 107 ? 15.730  11.584  2.188   1.00 24.25  ? 107 ILE C CG1 1 
ATOM   5353  C  CG2 . ILE C 1 107 ? 16.550  11.118  4.519   1.00 16.95  ? 107 ILE C CG2 1 
ATOM   5354  C  CD1 . ILE C 1 107 ? 15.613  13.109  2.322   1.00 23.91  ? 107 ILE C CD1 1 
ATOM   5355  N  N   . ARG C 1 108 ? 16.100  7.803   5.048   1.00 24.75  ? 108 ARG C N   1 
ATOM   5356  C  CA  . ARG C 1 108 ? 15.881  6.952   6.203   1.00 22.36  ? 108 ARG C CA  1 
ATOM   5357  C  C   . ARG C 1 108 ? 16.987  7.177   7.206   1.00 22.95  ? 108 ARG C C   1 
ATOM   5358  O  O   . ARG C 1 108 ? 18.127  7.423   6.875   1.00 21.14  ? 108 ARG C O   1 
ATOM   5359  C  CB  . ARG C 1 108 ? 15.856  5.460   5.840   1.00 23.91  ? 108 ARG C CB  1 
ATOM   5360  C  CG  . ARG C 1 108 ? 14.600  5.048   5.091   1.00 25.42  ? 108 ARG C CG  1 
ATOM   5361  C  CD  . ARG C 1 108 ? 14.681  3.624   4.583   1.00 24.58  ? 108 ARG C CD  1 
ATOM   5362  N  NE  . ARG C 1 108 ? 15.626  3.426   3.468   1.00 25.42  ? 108 ARG C NE  1 
ATOM   5363  C  CZ  . ARG C 1 108 ? 15.669  2.324   2.756   1.00 23.60  ? 108 ARG C CZ  1 
ATOM   5364  N  NH1 . ARG C 1 108 ? 14.864  1.350   3.060   1.00 25.50  ? 108 ARG C NH1 1 
ATOM   5365  N  NH2 . ARG C 1 108 ? 16.437  2.195   1.708   1.00 28.41  ? 108 ARG C NH2 1 
ATOM   5366  N  N   . ALA C 1 109 ? 16.639  7.018   8.463   1.00 27.84  ? 109 ALA C N   1 
ATOM   5367  C  CA  . ALA C 1 109 ? 17.628  7.086   9.516   1.00 30.56  ? 109 ALA C CA  1 
ATOM   5368  C  C   . ALA C 1 109 ? 17.029  6.506   10.803  1.00 26.85  ? 109 ALA C C   1 
ATOM   5369  O  O   . ALA C 1 109 ? 15.829  6.271   10.893  1.00 19.01  ? 109 ALA C O   1 
ATOM   5370  C  CB  . ALA C 1 109 ? 18.053  8.544   9.730   1.00 24.23  ? 109 ALA C CB  1 
ATOM   5371  N  N   . SER C 1 110 ? 17.861  6.479   11.842  1.00 25.02  ? 110 SER C N   1 
ATOM   5372  C  CA  . SER C 1 110 ? 17.388  6.016   13.134  1.00 27.28  ? 110 SER C CA  1 
ATOM   5373  C  C   . SER C 1 110 ? 16.698  7.159   13.852  1.00 24.53  ? 110 SER C C   1 
ATOM   5374  O  O   . SER C 1 110 ? 16.176  6.937   14.873  1.00 24.31  ? 110 SER C O   1 
ATOM   5375  C  CB  . SER C 1 110 ? 18.518  5.467   13.972  1.00 28.29  ? 110 SER C CB  1 
ATOM   5376  O  OG  . SER C 1 110 ? 19.422  6.519   14.290  1.00 39.88  ? 110 SER C OG  1 
ATOM   5377  N  N   . ARG C 1 111 ? 16.681  8.377   13.333  1.00 23.52  ? 111 ARG C N   1 
ATOM   5378  C  CA  . ARG C 1 111 ? 16.032  9.474   13.987  1.00 24.32  ? 111 ARG C CA  1 
ATOM   5379  C  C   . ARG C 1 111 ? 15.520  10.438  12.939  1.00 20.35  ? 111 ARG C C   1 
ATOM   5380  O  O   . ARG C 1 111 ? 16.200  10.689  11.941  1.00 21.93  ? 111 ARG C O   1 
ATOM   5381  C  CB  . ARG C 1 111 ? 17.137  10.269  14.718  1.00 32.01  ? 111 ARG C CB  1 
ATOM   5382  C  CG  . ARG C 1 111 ? 18.376  9.651   15.326  1.00 36.47  ? 111 ARG C CG  1 
ATOM   5383  C  CD  . ARG C 1 111 ? 19.002  10.516  16.431  1.00 43.24  ? 111 ARG C CD  1 
ATOM   5384  N  NE  . ARG C 1 111 ? 19.632  11.750  15.955  1.00 60.03  ? 111 ARG C NE  1 
ATOM   5385  C  CZ  . ARG C 1 111 ? 20.977  12.109  15.903  1.00 66.27  ? 111 ARG C CZ  1 
ATOM   5386  N  NH1 . ARG C 1 111 ? 21.932  11.182  15.985  1.00 56.60  ? 111 ARG C NH1 1 
ATOM   5387  N  NH2 . ARG C 1 111 ? 21.400  13.400  15.770  1.00 58.10  ? 111 ARG C NH2 1 
ATOM   5388  N  N   . LEU C 1 112 ? 14.403  11.094  13.211  1.00 20.38  ? 112 LEU C N   1 
ATOM   5389  C  CA  . LEU C 1 112 ? 13.820  12.038  12.245  1.00 24.61  ? 112 LEU C CA  1 
ATOM   5390  C  C   . LEU C 1 112 ? 14.695  13.235  11.898  1.00 24.54  ? 112 LEU C C   1 
ATOM   5391  O  O   . LEU C 1 112 ? 14.709  13.673  10.771  1.00 22.15  ? 112 LEU C O   1 
ATOM   5392  C  CB  . LEU C 1 112 ? 12.494  12.583  12.714  1.00 24.04  ? 112 LEU C CB  1 
ATOM   5393  C  CG  . LEU C 1 112 ? 11.665  13.257  11.633  1.00 27.33  ? 112 LEU C CG  1 
ATOM   5394  C  CD1 . LEU C 1 112 ? 11.479  12.340  10.463  1.00 29.06  ? 112 LEU C CD1 1 
ATOM   5395  C  CD2 . LEU C 1 112 ? 10.319  13.606  12.227  1.00 26.16  ? 112 LEU C CD2 1 
ATOM   5396  N  N   . ASP C 1 113 ? 15.434  13.768  12.875  1.00 26.73  ? 113 ASP C N   1 
ATOM   5397  C  CA  . ASP C 1 113 ? 16.127  15.043  12.724  1.00 28.25  ? 113 ASP C CA  1 
ATOM   5398  C  C   . ASP C 1 113 ? 17.151  14.917  11.604  1.00 25.76  ? 113 ASP C C   1 
ATOM   5399  O  O   . ASP C 1 113 ? 17.429  15.868  10.923  1.00 22.41  ? 113 ASP C O   1 
ATOM   5400  C  CB  . ASP C 1 113 ? 16.792  15.466  14.054  1.00 34.65  ? 113 ASP C CB  1 
ATOM   5401  C  CG  . ASP C 1 113 ? 17.894  14.567  14.642  1.00 32.82  ? 113 ASP C CG  1 
ATOM   5402  O  OD1 . ASP C 1 113 ? 17.790  13.373  14.496  1.00 40.79  ? 113 ASP C OD1 1 
ATOM   5403  O  OD2 . ASP C 1 113 ? 18.912  15.036  15.190  1.00 29.56  ? 113 ASP C OD2 1 
ATOM   5404  N  N   . LEU C 1 114 ? 17.772  13.746  11.460  1.00 24.03  ? 114 LEU C N   1 
ATOM   5405  C  CA  . LEU C 1 114 ? 18.769  13.557  10.442  1.00 28.45  ? 114 LEU C CA  1 
ATOM   5406  C  C   . LEU C 1 114 ? 18.095  13.528  9.079   1.00 26.75  ? 114 LEU C C   1 
ATOM   5407  O  O   . LEU C 1 114 ? 18.637  14.076  8.131   1.00 26.36  ? 114 LEU C O   1 
ATOM   5408  C  CB  . LEU C 1 114 ? 19.487  12.245  10.703  1.00 31.15  ? 114 LEU C CB  1 
ATOM   5409  C  CG  . LEU C 1 114 ? 20.431  12.241  11.915  1.00 32.31  ? 114 LEU C CG  1 
ATOM   5410  C  CD1 . LEU C 1 114 ? 20.930  10.816  12.123  1.00 33.79  ? 114 LEU C CD1 1 
ATOM   5411  C  CD2 . LEU C 1 114 ? 21.627  13.111  11.701  1.00 31.10  ? 114 LEU C CD2 1 
ATOM   5412  N  N   . CYS C 1 115 ? 16.944  12.855  9.001   1.00 22.14  ? 115 CYS C N   1 
ATOM   5413  C  CA  . CYS C 1 115 ? 16.163  12.862  7.782   1.00 20.57  ? 115 CYS C CA  1 
ATOM   5414  C  C   . CYS C 1 115 ? 15.798  14.282  7.367   1.00 18.65  ? 115 CYS C C   1 
ATOM   5415  O  O   . CYS C 1 115 ? 15.943  14.665  6.198   1.00 18.71  ? 115 CYS C O   1 
ATOM   5416  C  CB  . CYS C 1 115 ? 14.893  12.052  7.940   1.00 20.67  ? 115 CYS C CB  1 
ATOM   5417  S  SG  . CYS C 1 115 ? 15.206  10.305  8.179   1.00 21.62  ? 115 CYS C SG  1 
ATOM   5418  N  N   . PHE C 1 116 ? 15.313  15.052  8.337   1.00 17.78  ? 116 PHE C N   1 
ATOM   5419  C  CA  . PHE C 1 116 ? 14.880  16.407  8.071   1.00 19.06  ? 116 PHE C CA  1 
ATOM   5420  C  C   . PHE C 1 116 ? 16.043  17.297  7.643   1.00 21.30  ? 116 PHE C C   1 
ATOM   5421  O  O   . PHE C 1 116 ? 15.928  18.130  6.740   1.00 21.79  ? 116 PHE C O   1 
ATOM   5422  C  CB  . PHE C 1 116 ? 14.215  16.940  9.319   1.00 18.55  ? 116 PHE C CB  1 
ATOM   5423  C  CG  . PHE C 1 116 ? 13.475  18.238  9.087   1.00 19.26  ? 116 PHE C CG  1 
ATOM   5424  C  CD1 . PHE C 1 116 ? 14.132  19.440  9.187   1.00 18.92  ? 116 PHE C CD1 1 
ATOM   5425  C  CD2 . PHE C 1 116 ? 12.117  18.231  8.774   1.00 24.26  ? 116 PHE C CD2 1 
ATOM   5426  C  CE1 . PHE C 1 116 ? 13.450  20.619  9.089   1.00 20.19  ? 116 PHE C CE1 1 
ATOM   5427  C  CE2 . PHE C 1 116 ? 11.429  19.433  8.666   1.00 22.57  ? 116 PHE C CE2 1 
ATOM   5428  C  CZ  . PHE C 1 116 ? 12.114  20.625  8.799   1.00 21.46  ? 116 PHE C CZ  1 
ATOM   5429  N  N   . ALA C 1 117 ? 17.193  17.081  8.262   1.00 19.80  ? 117 ALA C N   1 
ATOM   5430  C  CA  . ALA C 1 117 ? 18.336  17.893  7.965   1.00 20.94  ? 117 ALA C CA  1 
ATOM   5431  C  C   . ALA C 1 117 ? 18.808  17.651  6.542   1.00 21.16  ? 117 ALA C C   1 
ATOM   5432  O  O   . ALA C 1 117 ? 19.135  18.613  5.825   1.00 20.01  ? 117 ALA C O   1 
ATOM   5433  C  CB  . ALA C 1 117 ? 19.452  17.560  8.929   1.00 23.03  ? 117 ALA C CB  1 
ATOM   5434  N  N   . LEU C 1 118 ? 18.839  16.382  6.126   1.00 18.81  ? 118 LEU C N   1 
ATOM   5435  C  CA  . LEU C 1 118 ? 19.226  16.115  4.755   1.00 17.36  ? 118 LEU C CA  1 
ATOM   5436  C  C   . LEU C 1 118 ? 18.177  16.627  3.758   1.00 19.21  ? 118 LEU C C   1 
ATOM   5437  O  O   . LEU C 1 118 ? 18.533  17.218  2.735   1.00 18.79  ? 118 LEU C O   1 
ATOM   5438  C  CB  . LEU C 1 118 ? 19.523  14.638  4.590   1.00 16.58  ? 118 LEU C CB  1 
ATOM   5439  C  CG  . LEU C 1 118 ? 19.907  14.219  3.177   1.00 17.67  ? 118 LEU C CG  1 
ATOM   5440  C  CD1 . LEU C 1 118 ? 21.083  14.970  2.633   1.00 17.92  ? 118 LEU C CD1 1 
ATOM   5441  C  CD2 . LEU C 1 118 ? 20.168  12.707  3.149   1.00 21.33  ? 118 LEU C CD2 1 
ATOM   5442  N  N   . ALA C 1 119 ? 16.889  16.457  4.070   1.00 20.43  ? 119 ALA C N   1 
ATOM   5443  C  CA  . ALA C 1 119 ? 15.829  16.950  3.195   1.00 19.91  ? 119 ALA C CA  1 
ATOM   5444  C  C   . ALA C 1 119 ? 15.922  18.460  3.033   1.00 18.41  ? 119 ALA C C   1 
ATOM   5445  O  O   . ALA C 1 119 ? 15.637  18.996  1.988   1.00 18.48  ? 119 ALA C O   1 
ATOM   5446  C  CB  . ALA C 1 119 ? 14.470  16.542  3.762   1.00 20.90  ? 119 ALA C CB  1 
ATOM   5447  N  N   . THR C 1 120 ? 16.275  19.144  4.085   1.00 18.21  ? 120 THR C N   1 
ATOM   5448  C  CA  . THR C 1 120 ? 16.426  20.579  4.064   1.00 18.36  ? 120 THR C CA  1 
ATOM   5449  C  C   . THR C 1 120 ? 17.540  20.961  3.124   1.00 19.31  ? 120 THR C C   1 
ATOM   5450  O  O   . THR C 1 120 ? 17.402  21.890  2.342   1.00 20.83  ? 120 THR C O   1 
ATOM   5451  C  CB  . THR C 1 120 ? 16.721  21.059  5.492   1.00 22.21  ? 120 THR C CB  1 
ATOM   5452  O  OG1 . THR C 1 120 ? 15.528  20.927  6.243   1.00 22.82  ? 120 THR C OG1 1 
ATOM   5453  C  CG2 . THR C 1 120 ? 17.061  22.534  5.599   1.00 24.72  ? 120 THR C CG2 1 
ATOM   5454  N  N   . GLU C 1 121 ? 18.675  20.282  3.205   1.00 21.91  ? 121 GLU C N   1 
ATOM   5455  C  CA  . GLU C 1 121 ? 19.788  20.602  2.321   1.00 22.56  ? 121 GLU C CA  1 
ATOM   5456  C  C   . GLU C 1 121 ? 19.438  20.329  0.851   1.00 20.63  ? 121 GLU C C   1 
ATOM   5457  O  O   . GLU C 1 121 ? 19.769  21.116  -0.052  1.00 21.85  ? 121 GLU C O   1 
ATOM   5458  C  CB  . GLU C 1 121 ? 21.091  19.864  2.651   1.00 26.56  ? 121 GLU C CB  1 
ATOM   5459  C  CG  . GLU C 1 121 ? 21.787  20.369  3.904   1.00 28.61  ? 121 GLU C CG  1 
ATOM   5460  C  CD  . GLU C 1 121 ? 22.547  21.657  3.707   1.00 32.40  ? 121 GLU C CD  1 
ATOM   5461  O  OE1 . GLU C 1 121 ? 22.967  21.974  2.597   1.00 37.34  ? 121 GLU C OE1 1 
ATOM   5462  O  OE2 . GLU C 1 121 ? 22.717  22.334  4.715   1.00 44.72  ? 121 GLU C OE2 1 
ATOM   5463  N  N   . ILE C 1 122 ? 18.824  19.176  0.568   1.00 19.88  ? 122 ILE C N   1 
ATOM   5464  C  CA  . ILE C 1 122 ? 18.411  18.846  -0.800  1.00 20.62  ? 122 ILE C CA  1 
ATOM   5465  C  C   . ILE C 1 122 ? 17.462  19.912  -1.365  1.00 24.15  ? 122 ILE C C   1 
ATOM   5466  O  O   . ILE C 1 122 ? 17.728  20.515  -2.391  1.00 25.36  ? 122 ILE C O   1 
ATOM   5467  C  CB  . ILE C 1 122 ? 17.839  17.424  -0.848  1.00 18.96  ? 122 ILE C CB  1 
ATOM   5468  C  CG1 . ILE C 1 122 ? 18.967  16.427  -0.606  1.00 20.70  ? 122 ILE C CG1 1 
ATOM   5469  C  CG2 . ILE C 1 122 ? 17.133  17.164  -2.167  1.00 20.01  ? 122 ILE C CG2 1 
ATOM   5470  C  CD1 . ILE C 1 122 ? 18.500  15.026  -0.296  1.00 21.14  ? 122 ILE C CD1 1 
ATOM   5471  N  N   . MET C 1 123 ? 16.405  20.234  -0.634  1.00 26.05  ? 123 MET C N   1 
ATOM   5472  C  CA  . MET C 1 123 ? 15.409  21.172  -1.122  1.00 26.12  ? 123 MET C CA  1 
ATOM   5473  C  C   . MET C 1 123 ? 15.969  22.577  -1.198  1.00 25.90  ? 123 MET C C   1 
ATOM   5474  O  O   . MET C 1 123 ? 15.549  23.335  -2.063  1.00 31.01  ? 123 MET C O   1 
ATOM   5475  C  CB  . MET C 1 123 ? 14.132  21.178  -0.293  1.00 27.76  ? 123 MET C CB  1 
ATOM   5476  C  CG  . MET C 1 123 ? 13.376  19.897  -0.539  1.00 37.38  ? 123 MET C CG  1 
ATOM   5477  S  SD  . MET C 1 123 ? 12.605  19.760  -2.166  1.00 39.63  ? 123 MET C SD  1 
ATOM   5478  C  CE  . MET C 1 123 ? 11.874  21.416  -2.305  1.00 35.21  ? 123 MET C CE  1 
ATOM   5479  N  N   . GLY C 1 124 ? 16.893  22.911  -0.313  1.00 25.65  ? 124 GLY C N   1 
ATOM   5480  C  CA  . GLY C 1 124 ? 17.577  24.184  -0.397  1.00 24.87  ? 124 GLY C CA  1 
ATOM   5481  C  C   . GLY C 1 124 ? 18.278  24.381  -1.744  1.00 24.14  ? 124 GLY C C   1 
ATOM   5482  O  O   . GLY C 1 124 ? 18.213  25.436  -2.289  1.00 26.78  ? 124 GLY C O   1 
ATOM   5483  N  N   . ARG C 1 125 ? 18.945  23.385  -2.279  1.00 21.99  ? 125 ARG C N   1 
ATOM   5484  C  CA  . ARG C 1 125 ? 19.585  23.471  -3.574  1.00 22.68  ? 125 ARG C CA  1 
ATOM   5485  C  C   . ARG C 1 125 ? 18.547  23.466  -4.702  1.00 25.49  ? 125 ARG C C   1 
ATOM   5486  O  O   . ARG C 1 125 ? 18.827  23.935  -5.784  1.00 28.49  ? 125 ARG C O   1 
ATOM   5487  C  CB  . ARG C 1 125 ? 20.534  22.288  -3.778  1.00 26.40  ? 125 ARG C CB  1 
ATOM   5488  C  CG  . ARG C 1 125 ? 21.617  22.157  -2.713  1.00 34.67  ? 125 ARG C CG  1 
ATOM   5489  C  CD  . ARG C 1 125 ? 22.867  22.942  -2.940  1.00 43.99  ? 125 ARG C CD  1 
ATOM   5490  N  NE  . ARG C 1 125 ? 23.369  22.565  -4.273  1.00 62.80  ? 125 ARG C NE  1 
ATOM   5491  C  CZ  . ARG C 1 125 ? 24.302  21.608  -4.534  1.00 58.21  ? 125 ARG C CZ  1 
ATOM   5492  N  NH1 . ARG C 1 125 ? 25.095  21.158  -3.533  1.00 51.11  ? 125 ARG C NH1 1 
ATOM   5493  N  NH2 . ARG C 1 125 ? 24.402  21.163  -5.800  1.00 47.71  ? 125 ARG C NH2 1 
ATOM   5494  N  N   . LEU C 1 126 ? 17.345  22.914  -4.487  1.00 23.00  ? 126 LEU C N   1 
ATOM   5495  C  CA  . LEU C 1 126 ? 16.455  22.698  -5.584  1.00 21.99  ? 126 LEU C CA  1 
ATOM   5496  C  C   . LEU C 1 126 ? 15.368  23.757  -5.627  1.00 25.37  ? 126 LEU C C   1 
ATOM   5497  O  O   . LEU C 1 126 ? 14.516  23.683  -6.525  1.00 24.70  ? 126 LEU C O   1 
ATOM   5498  C  CB  . LEU C 1 126 ? 15.823  21.319  -5.465  1.00 21.56  ? 126 LEU C CB  1 
ATOM   5499  C  CG  . LEU C 1 126 ? 16.719  20.109  -5.724  1.00 23.67  ? 126 LEU C CG  1 
ATOM   5500  C  CD1 . LEU C 1 126 ? 15.831  18.858  -5.549  1.00 28.44  ? 126 LEU C CD1 1 
ATOM   5501  C  CD2 . LEU C 1 126 ? 17.355  20.110  -7.061  1.00 23.76  ? 126 LEU C CD2 1 
ATOM   5502  N  N   . ARG C 1 127 ? 15.292  24.687  -4.666  1.00 31.40  ? 127 ARG C N   1 
ATOM   5503  C  CA  . ARG C 1 127 ? 14.128  25.578  -4.723  1.00 38.84  ? 127 ARG C CA  1 
ATOM   5504  C  C   . ARG C 1 127 ? 14.273  26.453  -5.988  1.00 36.09  ? 127 ARG C C   1 
ATOM   5505  O  O   . ARG C 1 127 ? 15.308  26.656  -6.637  1.00 32.12  ? 127 ARG C O   1 
ATOM   5506  C  CB  . ARG C 1 127 ? 13.820  26.345  -3.447  1.00 39.27  ? 127 ARG C CB  1 
ATOM   5507  C  CG  . ARG C 1 127 ? 14.985  27.270  -3.211  1.00 39.09  ? 127 ARG C CG  1 
ATOM   5508  C  CD  . ARG C 1 127 ? 14.540  27.408  -1.778  1.00 47.56  ? 127 ARG C CD  1 
ATOM   5509  N  NE  . ARG C 1 127 ? 15.619  28.194  -1.183  1.00 45.58  ? 127 ARG C NE  1 
ATOM   5510  C  CZ  . ARG C 1 127 ? 15.457  28.964  -0.144  1.00 39.92  ? 127 ARG C CZ  1 
ATOM   5511  N  NH1 . ARG C 1 127 ? 14.294  29.442  0.238   1.00 50.06  ? 127 ARG C NH1 1 
ATOM   5512  N  NH2 . ARG C 1 127 ? 16.508  29.261  0.525   1.00 41.14  ? 127 ARG C NH2 1 
ATOM   5513  N  N   . GLY C 1 128 ? 13.167  26.790  -6.560  1.00 34.62  ? 128 GLY C N   1 
ATOM   5514  C  CA  . GLY C 1 128 ? 13.287  27.435  -7.848  1.00 33.39  ? 128 GLY C CA  1 
ATOM   5515  C  C   . GLY C 1 128 ? 13.294  26.419  -8.989  1.00 30.01  ? 128 GLY C C   1 
ATOM   5516  O  O   . GLY C 1 128 ? 12.974  26.825  -10.080 1.00 33.62  ? 128 GLY C O   1 
ATOM   5517  N  N   . ALA C 1 129 ? 13.599  25.143  -8.768  1.00 20.75  ? 129 ALA C N   1 
ATOM   5518  C  CA  . ALA C 1 129 ? 13.690  24.239  -9.883  1.00 21.16  ? 129 ALA C CA  1 
ATOM   5519  C  C   . ALA C 1 129 ? 12.681  23.142  -9.801  1.00 22.16  ? 129 ALA C C   1 
ATOM   5520  O  O   . ALA C 1 129 ? 12.463  22.456  -10.805 1.00 24.12  ? 129 ALA C O   1 
ATOM   5521  C  CB  . ALA C 1 129 ? 15.027  23.645  -9.995  1.00 22.32  ? 129 ALA C CB  1 
ATOM   5522  N  N   . VAL C 1 130 ? 12.114  22.944  -8.628  1.00 21.78  ? 130 VAL C N   1 
ATOM   5523  C  CA  . VAL C 1 130 ? 11.181  21.831  -8.498  1.00 23.74  ? 130 VAL C CA  1 
ATOM   5524  C  C   . VAL C 1 130 ? 9.978   22.319  -7.727  1.00 22.28  ? 130 VAL C C   1 
ATOM   5525  O  O   . VAL C 1 130 ? 10.062  23.330  -7.080  1.00 20.74  ? 130 VAL C O   1 
ATOM   5526  C  CB  . VAL C 1 130 ? 11.742  20.598  -7.782  1.00 22.66  ? 130 VAL C CB  1 
ATOM   5527  C  CG1 . VAL C 1 130 ? 12.970  20.094  -8.467  1.00 27.24  ? 130 VAL C CG1 1 
ATOM   5528  C  CG2 . VAL C 1 130 ? 12.074  20.906  -6.346  1.00 26.80  ? 130 VAL C CG2 1 
ATOM   5529  N  N   . THR C 1 131 ? 8.909   21.545  -7.782  1.00 27.36  ? 131 THR C N   1 
ATOM   5530  C  CA  . THR C 1 131 ? 7.672   21.801  -7.052  1.00 32.26  ? 131 THR C CA  1 
ATOM   5531  C  C   . THR C 1 131 ? 7.357   20.545  -6.227  1.00 28.53  ? 131 THR C C   1 
ATOM   5532  O  O   . THR C 1 131 ? 7.219   19.426  -6.787  1.00 25.93  ? 131 THR C O   1 
ATOM   5533  C  CB  . THR C 1 131 ? 6.520   22.130  -8.038  1.00 31.51  ? 131 THR C CB  1 
ATOM   5534  O  OG1 . THR C 1 131 ? 6.859   23.361  -8.690  1.00 29.33  ? 131 THR C OG1 1 
ATOM   5535  C  CG2 . THR C 1 131 ? 5.176   22.246  -7.328  1.00 28.29  ? 131 THR C CG2 1 
ATOM   5536  N  N   . PRO C 1 132 ? 7.208   20.678  -4.903  1.00 23.98  ? 132 PRO C N   1 
ATOM   5537  C  CA  . PRO C 1 132 ? 6.925   19.508  -4.076  1.00 26.18  ? 132 PRO C CA  1 
ATOM   5538  C  C   . PRO C 1 132 ? 5.569   18.942  -4.422  1.00 27.52  ? 132 PRO C C   1 
ATOM   5539  O  O   . PRO C 1 132 ? 4.669   19.699  -4.594  1.00 27.14  ? 132 PRO C O   1 
ATOM   5540  C  CB  . PRO C 1 132 ? 6.950   20.056  -2.662  1.00 30.41  ? 132 PRO C CB  1 
ATOM   5541  C  CG  . PRO C 1 132 ? 6.768   21.538  -2.831  1.00 27.50  ? 132 PRO C CG  1 
ATOM   5542  C  CD  . PRO C 1 132 ? 7.322   21.922  -4.155  1.00 26.69  ? 132 PRO C CD  1 
ATOM   5543  N  N   . GLN C 1 133 ? 5.414   17.640  -4.515  1.00 25.92  ? 133 GLN C N   1 
ATOM   5544  C  CA  . GLN C 1 133 ? 4.098   17.061  -4.721  1.00 22.69  ? 133 GLN C CA  1 
ATOM   5545  C  C   . GLN C 1 133 ? 3.662   16.284  -3.496  1.00 25.27  ? 133 GLN C C   1 
ATOM   5546  O  O   . GLN C 1 133 ? 2.482   16.175  -3.248  1.00 27.15  ? 133 GLN C O   1 
ATOM   5547  C  CB  . GLN C 1 133 ? 4.066   15.946  -5.771  1.00 25.64  ? 133 GLN C CB  1 
ATOM   5548  C  CG  . GLN C 1 133 ? 4.452   16.423  -7.160  1.00 35.21  ? 133 GLN C CG  1 
ATOM   5549  C  CD  . GLN C 1 133 ? 3.431   17.410  -7.656  1.00 42.06  ? 133 GLN C CD  1 
ATOM   5550  O  OE1 . GLN C 1 133 ? 2.245   17.116  -7.553  1.00 42.86  ? 133 GLN C OE1 1 
ATOM   5551  N  NE2 . GLN C 1 133 ? 3.856   18.590  -8.092  1.00 37.86  ? 133 GLN C NE2 1 
ATOM   5552  N  N   . ASP C 1 134 ? 4.571   15.601  -2.808  1.00 22.84  ? 134 ASP C N   1 
ATOM   5553  C  CA  . ASP C 1 134 ? 4.186   14.908  -1.591  1.00 22.41  ? 134 ASP C CA  1 
ATOM   5554  C  C   . ASP C 1 134 ? 5.387   14.902  -0.638  1.00 24.68  ? 134 ASP C C   1 
ATOM   5555  O  O   . ASP C 1 134 ? 6.536   14.862  -1.053  1.00 23.84  ? 134 ASP C O   1 
ATOM   5556  C  CB  . ASP C 1 134 ? 3.734   13.528  -1.961  1.00 23.36  ? 134 ASP C CB  1 
ATOM   5557  C  CG  . ASP C 1 134 ? 2.906   12.766  -0.948  1.00 27.44  ? 134 ASP C CG  1 
ATOM   5558  O  OD1 . ASP C 1 134 ? 2.325   13.436  -0.112  1.00 28.04  ? 134 ASP C OD1 1 
ATOM   5559  O  OD2 . ASP C 1 134 ? 2.908   11.514  -1.021  1.00 27.32  ? 134 ASP C OD2 1 
ATOM   5560  N  N   . GLU C 1 135 ? 5.103   15.013  0.657   1.00 25.78  ? 135 GLU C N   1 
ATOM   5561  C  CA  . GLU C 1 135 ? 6.093   15.001  1.726   1.00 21.97  ? 135 GLU C CA  1 
ATOM   5562  C  C   . GLU C 1 135 ? 5.483   14.220  2.886   1.00 22.82  ? 135 GLU C C   1 
ATOM   5563  O  O   . GLU C 1 135 ? 4.479   14.609  3.397   1.00 21.85  ? 135 GLU C O   1 
ATOM   5564  C  CB  . GLU C 1 135 ? 6.374   16.412  2.179   1.00 20.82  ? 135 GLU C CB  1 
ATOM   5565  C  CG  . GLU C 1 135 ? 7.445   16.478  3.245   1.00 24.83  ? 135 GLU C CG  1 
ATOM   5566  C  CD  . GLU C 1 135 ? 7.822   17.863  3.723   1.00 24.04  ? 135 GLU C CD  1 
ATOM   5567  O  OE1 . GLU C 1 135 ? 7.385   18.820  3.062   1.00 32.17  ? 135 GLU C OE1 1 
ATOM   5568  O  OE2 . GLU C 1 135 ? 8.514   17.944  4.779   1.00 28.51  ? 135 GLU C OE2 1 
ATOM   5569  N  N   . VAL C 1 136 ? 6.020   13.057  3.223   1.00 22.43  ? 136 VAL C N   1 
ATOM   5570  C  CA  . VAL C 1 136 ? 5.532   12.273  4.335   1.00 19.79  ? 136 VAL C CA  1 
ATOM   5571  C  C   . VAL C 1 136 ? 6.668   11.974  5.301   1.00 20.88  ? 136 VAL C C   1 
ATOM   5572  O  O   . VAL C 1 136 ? 7.759   11.609  4.892   1.00 19.31  ? 136 VAL C O   1 
ATOM   5573  C  CB  . VAL C 1 136 ? 4.929   10.991  3.764   1.00 21.98  ? 136 VAL C CB  1 
ATOM   5574  C  CG1 . VAL C 1 136 ? 4.470   10.051  4.839   1.00 25.07  ? 136 VAL C CG1 1 
ATOM   5575  C  CG2 . VAL C 1 136 ? 3.756   11.285  2.850   1.00 24.93  ? 136 VAL C CG2 1 
ATOM   5576  N  N   . HIS C 1 137 ? 6.377   12.188  6.587   1.00 22.44  ? 137 HIS C N   1 
ATOM   5577  C  CA  . HIS C 1 137 ? 7.238   11.913  7.725   1.00 21.91  ? 137 HIS C CA  1 
ATOM   5578  C  C   . HIS C 1 137 ? 6.758   10.614  8.362   1.00 20.70  ? 137 HIS C C   1 
ATOM   5579  O  O   . HIS C 1 137 ? 5.681   10.546  8.917   1.00 21.34  ? 137 HIS C O   1 
ATOM   5580  C  CB  . HIS C 1 137 ? 7.193   13.082  8.718   1.00 19.64  ? 137 HIS C CB  1 
ATOM   5581  C  CG  . HIS C 1 137 ? 7.719   14.390  8.116   1.00 21.31  ? 137 HIS C CG  1 
ATOM   5582  N  ND1 . HIS C 1 137 ? 8.020   15.482  8.892   1.00 22.18  ? 137 HIS C ND1 1 
ATOM   5583  C  CD2 . HIS C 1 137 ? 8.030   14.779  6.853   1.00 20.10  ? 137 HIS C CD2 1 
ATOM   5584  C  CE1 . HIS C 1 137 ? 8.473   16.470  8.136   1.00 25.86  ? 137 HIS C CE1 1 
ATOM   5585  N  NE2 . HIS C 1 137 ? 8.439   16.095  6.893   1.00 19.37  ? 137 HIS C NE2 1 
ATOM   5586  N  N   . GLY C 1 138 ? 7.507   9.544   8.185   1.00 19.64  ? 138 GLY C N   1 
ATOM   5587  C  CA  . GLY C 1 138 ? 7.078   8.252   8.679   1.00 19.17  ? 138 GLY C CA  1 
ATOM   5588  C  C   . GLY C 1 138 ? 7.781   7.886   9.958   1.00 19.10  ? 138 GLY C C   1 
ATOM   5589  O  O   . GLY C 1 138 ? 8.920   8.295   10.170  1.00 23.09  ? 138 GLY C O   1 
ATOM   5590  N  N   . PHE C 1 139 ? 7.126   7.031   10.751  1.00 18.44  ? 139 PHE C N   1 
ATOM   5591  C  CA  . PHE C 1 139 ? 7.682   6.510   11.972  1.00 19.82  ? 139 PHE C CA  1 
ATOM   5592  C  C   . PHE C 1 139 ? 7.300   5.068   12.165  1.00 19.54  ? 139 PHE C C   1 
ATOM   5593  O  O   . PHE C 1 139 ? 6.215   4.688   11.821  1.00 22.79  ? 139 PHE C O   1 
ATOM   5594  C  CB  . PHE C 1 139 ? 7.177   7.372   13.130  1.00 23.13  ? 139 PHE C CB  1 
ATOM   5595  C  CG  . PHE C 1 139 ? 5.677   7.535   13.190  1.00 26.00  ? 139 PHE C CG  1 
ATOM   5596  C  CD1 . PHE C 1 139 ? 4.922   6.607   13.920  1.00 27.87  ? 139 PHE C CD1 1 
ATOM   5597  C  CD2 . PHE C 1 139 ? 5.057   8.630   12.622  1.00 22.40  ? 139 PHE C CD2 1 
ATOM   5598  C  CE1 . PHE C 1 139 ? 3.556   6.753   14.023  1.00 26.24  ? 139 PHE C CE1 1 
ATOM   5599  C  CE2 . PHE C 1 139 ? 3.676   8.766   12.740  1.00 26.03  ? 139 PHE C CE2 1 
ATOM   5600  C  CZ  . PHE C 1 139 ? 2.926   7.813   13.426  1.00 23.04  ? 139 PHE C CZ  1 
ATOM   5601  N  N   . LYS C 1 140 ? 8.208   4.333   12.771  1.00 26.44  ? 140 LYS C N   1 
ATOM   5602  C  CA  . LYS C 1 140 ? 7.983   2.962   13.201  1.00 32.17  ? 140 LYS C CA  1 
ATOM   5603  C  C   . LYS C 1 140 ? 7.106   2.933   14.452  1.00 27.45  ? 140 LYS C C   1 
ATOM   5604  O  O   . LYS C 1 140 ? 7.128   3.828   15.293  1.00 24.06  ? 140 LYS C O   1 
ATOM   5605  C  CB  . LYS C 1 140 ? 9.303   2.244   13.455  1.00 41.55  ? 140 LYS C CB  1 
ATOM   5606  C  CG  . LYS C 1 140 ? 9.449   1.419   14.762  1.00 62.79  ? 140 LYS C CG  1 
ATOM   5607  C  CD  . LYS C 1 140 ? 10.766  0.650   14.934  1.00 63.26  ? 140 LYS C CD  1 
ATOM   5608  C  CE  . LYS C 1 140 ? 10.912  -0.005  16.262  1.00 66.73  ? 140 LYS C CE  1 
ATOM   5609  N  NZ  . LYS C 1 140 ? 11.287  -1.409  16.065  1.00 71.62  ? 140 LYS C NZ  1 
ATOM   5610  N  N   . TYR C 1 141 ? 6.200   1.963   14.436  1.00 25.39  ? 141 TYR C N   1 
ATOM   5611  C  CA  . TYR C 1 141 ? 5.076   1.899   15.356  1.00 34.90  ? 141 TYR C CA  1 
ATOM   5612  C  C   . TYR C 1 141 ? 5.205   0.579   16.108  1.00 36.95  ? 141 TYR C C   1 
ATOM   5613  O  O   . TYR C 1 141 ? 4.835   -0.486  15.617  1.00 44.01  ? 141 TYR C O   1 
ATOM   5614  C  CB  . TYR C 1 141 ? 3.840   2.086   14.469  1.00 38.23  ? 141 TYR C CB  1 
ATOM   5615  C  CG  . TYR C 1 141 ? 2.550   2.380   15.186  1.00 40.90  ? 141 TYR C CG  1 
ATOM   5616  C  CD1 . TYR C 1 141 ? 2.370   3.606   15.764  1.00 49.10  ? 141 TYR C CD1 1 
ATOM   5617  C  CD2 . TYR C 1 141 ? 1.513   1.466   15.237  1.00 59.25  ? 141 TYR C CD2 1 
ATOM   5618  C  CE1 . TYR C 1 141 ? 1.181   3.950   16.360  1.00 55.30  ? 141 TYR C CE1 1 
ATOM   5619  C  CE2 . TYR C 1 141 ? 0.320   1.775   15.862  1.00 64.54  ? 141 TYR C CE2 1 
ATOM   5620  C  CZ  . TYR C 1 141 ? 0.168   3.025   16.435  1.00 62.06  ? 141 TYR C CZ  1 
ATOM   5621  O  OH  . TYR C 1 141 ? -0.933  3.430   17.124  1.00 77.17  ? 141 TYR C OH  1 
ATOM   5622  N  N   . PHE C 1 142 ? 5.896   0.624   17.233  1.00 44.18  ? 142 PHE C N   1 
ATOM   5623  C  CA  . PHE C 1 142 ? 5.834   -0.464  18.195  1.00 48.11  ? 142 PHE C CA  1 
ATOM   5624  C  C   . PHE C 1 142 ? 6.832   -1.486  17.686  1.00 32.67  ? 142 PHE C C   1 
ATOM   5625  O  O   . PHE C 1 142 ? 7.871   -1.113  17.192  1.00 36.77  ? 142 PHE C O   1 
ATOM   5626  C  CB  . PHE C 1 142 ? 4.387   -0.924  18.535  1.00 52.93  ? 142 PHE C CB  1 
ATOM   5627  C  CG  . PHE C 1 142 ? 3.623   0.031   19.472  1.00 70.09  ? 142 PHE C CG  1 
ATOM   5628  C  CD1 . PHE C 1 142 ? 4.091   0.308   20.785  1.00 72.78  ? 142 PHE C CD1 1 
ATOM   5629  C  CD2 . PHE C 1 142 ? 2.460   0.670   19.029  1.00 63.99  ? 142 PHE C CD2 1 
ATOM   5630  C  CE1 . PHE C 1 142 ? 3.404   1.185   21.615  1.00 67.43  ? 142 PHE C CE1 1 
ATOM   5631  C  CE2 . PHE C 1 142 ? 1.762   1.530   19.873  1.00 67.50  ? 142 PHE C CE2 1 
ATOM   5632  C  CZ  . PHE C 1 142 ? 2.239   1.784   21.156  1.00 68.94  ? 142 PHE C CZ  1 
ATOM   5633  N  N   . ASP C 1 143 ? 6.415   -2.723  17.652  1.00 31.01  ? 143 ASP C N   1 
ATOM   5634  C  CA  . ASP C 1 143 ? 7.288   -3.809  17.274  1.00 30.89  ? 143 ASP C CA  1 
ATOM   5635  C  C   . ASP C 1 143 ? 7.086   -4.087  15.788  1.00 27.52  ? 143 ASP C C   1 
ATOM   5636  O  O   . ASP C 1 143 ? 6.549   -5.142  15.383  1.00 23.97  ? 143 ASP C O   1 
ATOM   5637  C  CB  . ASP C 1 143 ? 6.999   -4.973  18.201  1.00 36.98  ? 143 ASP C CB  1 
ATOM   5638  C  CG  . ASP C 1 143 ? 5.525   -5.340  18.321  1.00 38.90  ? 143 ASP C CG  1 
ATOM   5639  O  OD1 . ASP C 1 143 ? 4.686   -4.383  18.441  1.00 41.04  ? 143 ASP C OD1 1 
ATOM   5640  O  OD2 . ASP C 1 143 ? 5.270   -6.590  18.305  1.00 41.43  ? 143 ASP C OD2 1 
ATOM   5641  N  N   . GLU C 1 144 ? 7.535   -3.123  14.980  1.00 22.74  ? 144 GLU C N   1 
ATOM   5642  C  CA  . GLU C 1 144 ? 7.451   -3.236  13.533  1.00 25.42  ? 144 GLU C CA  1 
ATOM   5643  C  C   . GLU C 1 144 ? 5.996   -3.316  13.021  1.00 27.23  ? 144 GLU C C   1 
ATOM   5644  O  O   . GLU C 1 144 ? 5.766   -3.822  11.928  1.00 26.86  ? 144 GLU C O   1 
ATOM   5645  C  CB  . GLU C 1 144 ? 8.359   -4.357  13.020  1.00 25.93  ? 144 GLU C CB  1 
ATOM   5646  C  CG  . GLU C 1 144 ? 9.832   -4.064  13.292  1.00 33.00  ? 144 GLU C CG  1 
ATOM   5647  C  CD  . GLU C 1 144 ? 10.442  -2.868  12.553  1.00 35.44  ? 144 GLU C CD  1 
ATOM   5648  O  OE1 . GLU C 1 144 ? 9.925   -2.508  11.482  1.00 38.13  ? 144 GLU C OE1 1 
ATOM   5649  O  OE2 . GLU C 1 144 ? 11.453  -2.302  13.018  1.00 37.20  ? 144 GLU C OE2 1 
ATOM   5650  N  N   . ARG C 1 145 ? 5.022   -2.786  13.790  1.00 28.08  ? 145 ARG C N   1 
ATOM   5651  C  CA  . ARG C 1 145 ? 3.616   -2.830  13.411  1.00 24.97  ? 145 ARG C CA  1 
ATOM   5652  C  C   . ARG C 1 145 ? 3.264   -1.680  12.500  1.00 24.14  ? 145 ARG C C   1 
ATOM   5653  O  O   . ARG C 1 145 ? 4.012   -0.730  12.364  1.00 25.83  ? 145 ARG C O   1 
ATOM   5654  C  CB  . ARG C 1 145 ? 2.728   -2.941  14.632  1.00 25.69  ? 145 ARG C CB  1 
ATOM   5655  C  CG  . ARG C 1 145 ? 2.975   -4.321  15.247  1.00 29.03  ? 145 ARG C CG  1 
ATOM   5656  C  CD  . ARG C 1 145 ? 1.974   -4.624  16.315  1.00 28.99  ? 145 ARG C CD  1 
ATOM   5657  N  NE  . ARG C 1 145 ? 2.345   -5.832  17.020  1.00 32.37  ? 145 ARG C NE  1 
ATOM   5658  C  CZ  . ARG C 1 145 ? 1.918   -7.074  16.765  1.00 33.31  ? 145 ARG C CZ  1 
ATOM   5659  N  NH1 . ARG C 1 145 ? 0.942   -7.330  15.913  1.00 29.04  ? 145 ARG C NH1 1 
ATOM   5660  N  NH2 . ARG C 1 145 ? 2.555   -8.071  17.364  1.00 30.25  ? 145 ARG C NH2 1 
ATOM   5661  N  N   . ASP C 1 146 ? 2.222   -1.895  11.714  1.00 27.90  ? 146 ASP C N   1 
ATOM   5662  C  CA  . ASP C 1 146 ? 1.622   -0.838  10.897  1.00 27.88  ? 146 ASP C CA  1 
ATOM   5663  C  C   . ASP C 1 146 ? 0.344   -0.344  11.579  1.00 26.28  ? 146 ASP C C   1 
ATOM   5664  O  O   . ASP C 1 146 ? 0.015   -0.761  12.719  1.00 24.85  ? 146 ASP C O   1 
ATOM   5665  C  CB  . ASP C 1 146 ? 1.467   -1.269  9.445   1.00 25.06  ? 146 ASP C CB  1 
ATOM   5666  C  CG  . ASP C 1 146 ? 0.571   -2.456  9.229   1.00 26.35  ? 146 ASP C CG  1 
ATOM   5667  O  OD1 . ASP C 1 146 ? -0.302  -2.674  10.092  1.00 22.72  ? 146 ASP C OD1 1 
ATOM   5668  O  OD2 . ASP C 1 146 ? 0.797   -3.150  8.226   1.00 27.39  ? 146 ASP C OD2 1 
ATOM   5669  N  N   . MET C 1 147 ? -0.328  0.555   10.873  1.00 24.04  ? 147 MET C N   1 
ATOM   5670  C  CA  . MET C 1 147 ? -1.475  1.225   11.447  1.00 27.04  ? 147 MET C CA  1 
ATOM   5671  C  C   . MET C 1 147 ? -2.609  0.221   11.622  1.00 24.90  ? 147 MET C C   1 
ATOM   5672  O  O   . MET C 1 147 ? -3.506  0.497   12.394  1.00 31.05  ? 147 MET C O   1 
ATOM   5673  C  CB  . MET C 1 147 ? -2.000  2.341   10.533  1.00 32.02  ? 147 MET C CB  1 
ATOM   5674  C  CG  . MET C 1 147 ? -1.230  3.578   10.580  1.00 38.19  ? 147 MET C CG  1 
ATOM   5675  S  SD  . MET C 1 147 ? -1.476  4.369   12.165  1.00 34.06  ? 147 MET C SD  1 
ATOM   5676  C  CE  . MET C 1 147 ? -0.306  5.713   11.992  1.00 45.05  ? 147 MET C CE  1 
ATOM   5677  N  N   . LEU C 1 148 ? -2.625  -0.908  10.892  1.00 22.94  ? 148 LEU C N   1 
ATOM   5678  C  CA  . LEU C 1 148 ? -3.668  -1.919  11.047  1.00 18.99  ? 148 LEU C CA  1 
ATOM   5679  C  C   . LEU C 1 148 ? -3.354  -2.835  12.225  1.00 23.67  ? 148 LEU C C   1 
ATOM   5680  O  O   . LEU C 1 148 ? -4.146  -3.697  12.577  1.00 22.34  ? 148 LEU C O   1 
ATOM   5681  C  CB  . LEU C 1 148 ? -3.817  -2.742  9.781   1.00 20.85  ? 148 LEU C CB  1 
ATOM   5682  C  CG  . LEU C 1 148 ? -4.156  -1.967  8.507   1.00 26.43  ? 148 LEU C CG  1 
ATOM   5683  C  CD1 . LEU C 1 148 ? -4.302  -2.937  7.359   1.00 32.16  ? 148 LEU C CD1 1 
ATOM   5684  C  CD2 . LEU C 1 148 ? -5.442  -1.169  8.605   1.00 25.68  ? 148 LEU C CD2 1 
ATOM   5685  N  N   . GLY C 1 149 ? -2.187  -2.682  12.870  1.00 24.13  ? 149 GLY C N   1 
ATOM   5686  C  CA  . GLY C 1 149 ? -1.849  -3.437  14.064  1.00 19.31  ? 149 GLY C CA  1 
ATOM   5687  C  C   . GLY C 1 149 ? -1.131  -4.738  13.764  1.00 19.22  ? 149 GLY C C   1 
ATOM   5688  O  O   . GLY C 1 149 ? -0.890  -5.496  14.666  1.00 20.19  ? 149 GLY C O   1 
ATOM   5689  N  N   . PHE C 1 150 ? -0.736  -4.973  12.523  1.00 20.49  ? 150 PHE C N   1 
ATOM   5690  C  CA  . PHE C 1 150 ? -0.015  -6.165  12.125  1.00 23.30  ? 150 PHE C CA  1 
ATOM   5691  C  C   . PHE C 1 150 ? 1.468   -5.839  11.920  1.00 26.50  ? 150 PHE C C   1 
ATOM   5692  O  O   . PHE C 1 150 ? 1.830   -4.746  11.462  1.00 24.38  ? 150 PHE C O   1 
ATOM   5693  C  CB  . PHE C 1 150 ? -0.580  -6.705  10.799  1.00 26.18  ? 150 PHE C CB  1 
ATOM   5694  C  CG  . PHE C 1 150 ? -1.885  -7.469  11.033  1.00 24.83  ? 150 PHE C CG  1 
ATOM   5695  C  CD1 . PHE C 1 150 ? -3.039  -6.817  11.414  1.00 19.24  ? 150 PHE C CD1 1 
ATOM   5696  C  CD2 . PHE C 1 150 ? -1.918  -8.845  10.931  1.00 22.17  ? 150 PHE C CD2 1 
ATOM   5697  C  CE1 . PHE C 1 150 ? -4.192  -7.534  11.666  1.00 22.38  ? 150 PHE C CE1 1 
ATOM   5698  C  CE2 . PHE C 1 150 ? -3.074  -9.553  11.215  1.00 24.53  ? 150 PHE C CE2 1 
ATOM   5699  C  CZ  . PHE C 1 150 ? -4.223  -8.899  11.546  1.00 22.86  ? 150 PHE C CZ  1 
ATOM   5700  N  N   . VAL C 1 151 ? 2.310   -6.831  12.217  1.00 25.03  ? 151 VAL C N   1 
ATOM   5701  C  CA  . VAL C 1 151 ? 3.722   -6.733  11.918  1.00 26.82  ? 151 VAL C CA  1 
ATOM   5702  C  C   . VAL C 1 151 ? 3.913   -6.675  10.394  1.00 23.93  ? 151 VAL C C   1 
ATOM   5703  O  O   . VAL C 1 151 ? 3.304   -7.415  9.636   1.00 21.73  ? 151 VAL C O   1 
ATOM   5704  C  CB  . VAL C 1 151 ? 4.462   -7.946  12.519  1.00 29.16  ? 151 VAL C CB  1 
ATOM   5705  C  CG1 . VAL C 1 151 ? 5.945   -7.865  12.248  1.00 31.62  ? 151 VAL C CG1 1 
ATOM   5706  C  CG2 . VAL C 1 151 ? 4.209   -8.128  14.007  1.00 31.83  ? 151 VAL C CG2 1 
ATOM   5707  N  N   . ASP C 1 152 ? 4.795   -5.781  9.966   1.00 25.65  ? 152 ASP C N   1 
ATOM   5708  C  CA  . ASP C 1 152 ? 4.930   -5.352  8.587   1.00 29.51  ? 152 ASP C CA  1 
ATOM   5709  C  C   . ASP C 1 152 ? 6.410   -5.432  8.199   1.00 26.00  ? 152 ASP C C   1 
ATOM   5710  O  O   . ASP C 1 152 ? 7.227   -4.724  8.770   1.00 28.74  ? 152 ASP C O   1 
ATOM   5711  C  CB  . ASP C 1 152 ? 4.316   -3.959  8.446   1.00 34.80  ? 152 ASP C CB  1 
ATOM   5712  C  CG  . ASP C 1 152 ? 4.076   -3.514  7.013   1.00 42.37  ? 152 ASP C CG  1 
ATOM   5713  O  OD1 . ASP C 1 152 ? 5.040   -3.748  6.243   1.00 37.19  ? 152 ASP C OD1 1 
ATOM   5714  O  OD2 . ASP C 1 152 ? 2.981   -2.853  6.727   1.00 47.71  ? 152 ASP C OD2 1 
ATOM   5715  N  N   . GLY C 1 153 ? 6.723   -6.372  7.298   1.00 22.50  ? 153 GLY C N   1 
ATOM   5716  C  CA  . GLY C 1 153 ? 8.082   -6.600  6.808   1.00 24.54  ? 153 GLY C CA  1 
ATOM   5717  C  C   . GLY C 1 153 ? 8.605   -8.045  6.947   1.00 24.32  ? 153 GLY C C   1 
ATOM   5718  O  O   . GLY C 1 153 ? 9.653   -8.365  6.419   1.00 26.84  ? 153 GLY C O   1 
ATOM   5719  N  N   . THR C 1 154 ? 7.847   -8.916  7.626   1.00 20.60  ? 154 THR C N   1 
ATOM   5720  C  CA  . THR C 1 154 ? 8.337   -10.152 8.137   1.00 24.40  ? 154 THR C CA  1 
ATOM   5721  C  C   . THR C 1 154 ? 8.931   -10.997 7.012   1.00 28.72  ? 154 THR C C   1 
ATOM   5722  O  O   . THR C 1 154 ? 9.926   -11.698 7.199   1.00 28.01  ? 154 THR C O   1 
ATOM   5723  C  CB  . THR C 1 154 ? 7.134   -10.861 8.726   1.00 29.52  ? 154 THR C CB  1 
ATOM   5724  O  OG1 . THR C 1 154 ? 6.445   -9.908  9.542   1.00 28.25  ? 154 THR C OG1 1 
ATOM   5725  C  CG2 . THR C 1 154 ? 7.493   -12.214 9.353   1.00 30.25  ? 154 THR C CG2 1 
ATOM   5726  N  N   . GLU C 1 155 ? 8.273   -11.035 5.858   1.00 26.91  ? 155 GLU C N   1 
ATOM   5727  C  CA  . GLU C 1 155 ? 8.681   -11.947 4.807   1.00 26.56  ? 155 GLU C CA  1 
ATOM   5728  C  C   . GLU C 1 155 ? 9.560   -11.232 3.780   1.00 27.69  ? 155 GLU C C   1 
ATOM   5729  O  O   . GLU C 1 155 ? 9.865   -11.784 2.742   1.00 28.59  ? 155 GLU C O   1 
ATOM   5730  C  CB  . GLU C 1 155 ? 7.466   -12.592 4.147   1.00 30.25  ? 155 GLU C CB  1 
ATOM   5731  C  CG  . GLU C 1 155 ? 6.828   -13.647 5.055   1.00 31.88  ? 155 GLU C CG  1 
ATOM   5732  C  CD  . GLU C 1 155 ? 7.717   -14.862 5.218   1.00 31.22  ? 155 GLU C CD  1 
ATOM   5733  O  OE1 . GLU C 1 155 ? 8.168   -15.452 4.222   1.00 33.25  ? 155 GLU C OE1 1 
ATOM   5734  O  OE2 . GLU C 1 155 ? 7.967   -15.219 6.351   1.00 33.28  ? 155 GLU C OE2 1 
ATOM   5735  N  N   . ASN C 1 156 ? 10.041  -10.034 4.041   1.00 24.75  ? 156 ASN C N   1 
ATOM   5736  C  CA  . ASN C 1 156 ? 10.971  -9.427  3.121   1.00 24.55  ? 156 ASN C CA  1 
ATOM   5737  C  C   . ASN C 1 156 ? 12.131  -10.364 2.894   1.00 25.87  ? 156 ASN C C   1 
ATOM   5738  O  O   . ASN C 1 156 ? 12.505  -11.049 3.818   1.00 30.25  ? 156 ASN C O   1 
ATOM   5739  C  CB  . ASN C 1 156 ? 11.558  -8.136  3.656   1.00 23.27  ? 156 ASN C CB  1 
ATOM   5740  C  CG  . ASN C 1 156 ? 10.793  -6.934  3.180   1.00 27.08  ? 156 ASN C CG  1 
ATOM   5741  O  OD1 . ASN C 1 156 ? 10.274  -6.869  2.055   1.00 32.85  ? 156 ASN C OD1 1 
ATOM   5742  N  ND2 . ASN C 1 156 ? 10.675  -5.966  4.051   1.00 28.66  ? 156 ASN C ND2 1 
ATOM   5743  N  N   . PRO C 1 157 ? 12.796  -10.357 1.727   1.00 29.19  ? 157 PRO C N   1 
ATOM   5744  C  CA  . PRO C 1 157 ? 14.033  -11.127 1.540   1.00 33.64  ? 157 PRO C CA  1 
ATOM   5745  C  C   . PRO C 1 157 ? 15.190  -10.405 2.235   1.00 33.37  ? 157 PRO C C   1 
ATOM   5746  O  O   . PRO C 1 157 ? 15.130  -9.183  2.430   1.00 27.02  ? 157 PRO C O   1 
ATOM   5747  C  CB  . PRO C 1 157 ? 14.221  -11.249 0.002   1.00 32.84  ? 157 PRO C CB  1 
ATOM   5748  C  CG  . PRO C 1 157 ? 13.554  -9.989  -0.494  1.00 33.32  ? 157 PRO C CG  1 
ATOM   5749  C  CD  . PRO C 1 157 ? 12.419  -9.638  0.503   1.00 32.94  ? 157 PRO C CD  1 
ATOM   5750  N  N   . THR C 1 158 ? 16.219  -11.209 2.587   1.00 33.58  ? 158 THR C N   1 
ATOM   5751  C  CA  . THR C 1 158 ? 17.418  -10.726 3.248   1.00 33.99  ? 158 THR C CA  1 
ATOM   5752  C  C   . THR C 1 158 ? 18.655  -11.312 2.553   1.00 35.82  ? 158 THR C C   1 
ATOM   5753  O  O   . THR C 1 158 ? 18.578  -12.305 1.804   1.00 31.68  ? 158 THR C O   1 
ATOM   5754  C  CB  . THR C 1 158 ? 17.448  -11.041 4.749   1.00 33.35  ? 158 THR C CB  1 
ATOM   5755  O  OG1 . THR C 1 158 ? 17.225  -12.433 4.739   1.00 37.42  ? 158 THR C OG1 1 
ATOM   5756  C  CG2 . THR C 1 158 ? 16.295  -10.537 5.573   1.00 38.25  ? 158 THR C CG2 1 
ATOM   5757  N  N   . GLY C 1 159 ? 19.797  -10.625 2.846   1.00 46.36  ? 159 GLY C N   1 
ATOM   5758  C  CA  . GLY C 1 159 ? 21.133  -10.954 2.357   1.00 42.31  ? 159 GLY C CA  1 
ATOM   5759  C  C   . GLY C 1 159 ? 21.107  -11.239 0.855   1.00 42.75  ? 159 GLY C C   1 
ATOM   5760  O  O   . GLY C 1 159 ? 20.654  -10.409 0.054   1.00 52.14  ? 159 GLY C O   1 
ATOM   5761  N  N   . ALA C 1 160 ? 21.608  -12.408 0.464   1.00 39.80  ? 160 ALA C N   1 
ATOM   5762  C  CA  . ALA C 1 160 ? 21.858  -12.660 -0.948  1.00 44.30  ? 160 ALA C CA  1 
ATOM   5763  C  C   . ALA C 1 160 ? 20.528  -12.680 -1.728  1.00 42.09  ? 160 ALA C C   1 
ATOM   5764  O  O   . ALA C 1 160 ? 20.447  -12.207 -2.859  1.00 37.55  ? 160 ALA C O   1 
ATOM   5765  C  CB  . ALA C 1 160 ? 22.654  -13.952 -1.093  1.00 41.21  ? 160 ALA C CB  1 
ATOM   5766  N  N   . ALA C 1 161 ? 19.449  -13.168 -1.095  1.00 39.71  ? 161 ALA C N   1 
ATOM   5767  C  CA  . ALA C 1 161 ? 18.185  -13.258 -1.795  1.00 37.29  ? 161 ALA C CA  1 
ATOM   5768  C  C   . ALA C 1 161 ? 17.670  -11.853 -2.113  1.00 40.61  ? 161 ALA C C   1 
ATOM   5769  O  O   . ALA C 1 161 ? 17.032  -11.639 -3.153  1.00 37.21  ? 161 ALA C O   1 
ATOM   5770  C  CB  . ALA C 1 161 ? 17.209  -14.031 -0.967  1.00 46.10  ? 161 ALA C CB  1 
ATOM   5771  N  N   . ALA C 1 162 ? 17.928  -10.905 -1.194  1.00 38.51  ? 162 ALA C N   1 
ATOM   5772  C  CA  . ALA C 1 162 ? 17.518  -9.524  -1.412  1.00 35.44  ? 162 ALA C CA  1 
ATOM   5773  C  C   . ALA C 1 162 ? 18.291  -8.905  -2.566  1.00 37.91  ? 162 ALA C C   1 
ATOM   5774  O  O   . ALA C 1 162 ? 17.620  -8.336  -3.423  1.00 38.91  ? 162 ALA C O   1 
ATOM   5775  C  CB  . ALA C 1 162 ? 17.725  -8.717  -0.153  1.00 38.96  ? 162 ALA C CB  1 
ATOM   5776  N  N   . ARG C 1 163 ? 19.656  -9.016  -2.563  1.00 42.57  ? 163 ARG C N   1 
ATOM   5777  C  CA  . ARG C 1 163 ? 20.540  -8.548  -3.640  1.00 37.79  ? 163 ARG C CA  1 
ATOM   5778  C  C   . ARG C 1 163 ? 19.908  -9.039  -4.950  1.00 32.64  ? 163 ARG C C   1 
ATOM   5779  O  O   . ARG C 1 163 ? 19.703  -8.237  -5.866  1.00 35.05  ? 163 ARG C O   1 
ATOM   5780  C  CB  . ARG C 1 163 ? 22.053  -8.894  -3.511  1.00 43.57  ? 163 ARG C CB  1 
ATOM   5781  C  CG  . ARG C 1 163 ? 23.140  -8.325  -2.560  1.00 55.84  ? 163 ARG C CG  1 
ATOM   5782  C  CD  . ARG C 1 163 ? 24.433  -9.286  -2.263  1.00 46.64  ? 163 ARG C CD  1 
ATOM   5783  N  N   . ARG C 1 164 ? 19.508  -10.330 -5.034  1.00 30.67  ? 164 ARG C N   1 
ATOM   5784  C  CA  . ARG C 1 164 ? 19.110  -10.944 -6.298  1.00 33.20  ? 164 ARG C CA  1 
ATOM   5785  C  C   . ARG C 1 164 ? 17.716  -10.463 -6.679  1.00 34.97  ? 164 ARG C C   1 
ATOM   5786  O  O   . ARG C 1 164 ? 17.378  -10.415 -7.842  1.00 33.63  ? 164 ARG C O   1 
ATOM   5787  C  CB  . ARG C 1 164 ? 19.235  -12.477 -6.339  1.00 43.08  ? 164 ARG C CB  1 
ATOM   5788  C  CG  . ARG C 1 164 ? 19.581  -13.123 -7.686  1.00 69.78  ? 164 ARG C CG  1 
ATOM   5789  C  CD  . ARG C 1 164 ? 20.272  -14.527 -7.628  1.00 75.70  ? 164 ARG C CD  1 
ATOM   5790  N  NE  . ARG C 1 164 ? 19.403  -15.411 -6.839  1.00 83.42  ? 164 ARG C NE  1 
ATOM   5791  C  CZ  . ARG C 1 164 ? 19.479  -15.747 -5.529  1.00 74.04  ? 164 ARG C CZ  1 
ATOM   5792  N  NH1 . ARG C 1 164 ? 20.618  -15.681 -4.863  1.00 65.30  ? 164 ARG C NH1 1 
ATOM   5793  N  NH2 . ARG C 1 164 ? 18.396  -16.207 -4.900  1.00 66.41  ? 164 ARG C NH2 1 
ATOM   5794  N  N   . ALA C 1 165 ? 16.868  -10.076 -5.722  1.00 39.12  ? 165 ALA C N   1 
ATOM   5795  C  CA  . ALA C 1 165 ? 15.506  -9.709  -6.086  1.00 31.39  ? 165 ALA C CA  1 
ATOM   5796  C  C   . ALA C 1 165 ? 15.422  -8.250  -6.479  1.00 27.47  ? 165 ALA C C   1 
ATOM   5797  O  O   . ALA C 1 165 ? 14.490  -7.869  -7.140  1.00 24.99  ? 165 ALA C O   1 
ATOM   5798  C  CB  . ALA C 1 165 ? 14.576  -10.011 -4.951  1.00 29.96  ? 165 ALA C CB  1 
ATOM   5799  N  N   . VAL C 1 166 ? 16.358  -7.430  -6.049  1.00 30.17  ? 166 VAL C N   1 
ATOM   5800  C  CA  . VAL C 1 166 ? 16.189  -5.981  -6.092  1.00 34.34  ? 166 VAL C CA  1 
ATOM   5801  C  C   . VAL C 1 166 ? 17.090  -5.280  -7.119  1.00 32.00  ? 166 VAL C C   1 
ATOM   5802  O  O   . VAL C 1 166 ? 16.700  -4.261  -7.704  1.00 28.42  ? 166 VAL C O   1 
ATOM   5803  C  CB  . VAL C 1 166 ? 16.476  -5.479  -4.665  1.00 35.86  ? 166 VAL C CB  1 
ATOM   5804  C  CG1 . VAL C 1 166 ? 16.686  -4.012  -4.655  1.00 33.82  ? 166 VAL C CG1 1 
ATOM   5805  C  CG2 . VAL C 1 166 ? 15.349  -5.801  -3.700  1.00 38.03  ? 166 VAL C CG2 1 
ATOM   5806  N  N   . LEU C 1 167 ? 18.323  -5.760  -7.309  1.00 31.42  ? 167 LEU C N   1 
ATOM   5807  C  CA  . LEU C 1 167 ? 19.303  -5.043  -8.136  1.00 32.69  ? 167 LEU C CA  1 
ATOM   5808  C  C   . LEU C 1 167 ? 19.324  -5.543  -9.582  1.00 32.69  ? 167 LEU C C   1 
ATOM   5809  O  O   . LEU C 1 167 ? 19.362  -6.754  -9.830  1.00 36.62  ? 167 LEU C O   1 
ATOM   5810  C  CB  . LEU C 1 167 ? 20.686  -5.211  -7.531  1.00 32.94  ? 167 LEU C CB  1 
ATOM   5811  C  CG  . LEU C 1 167 ? 20.893  -4.655  -6.127  1.00 38.19  ? 167 LEU C CG  1 
ATOM   5812  C  CD1 . LEU C 1 167 ? 22.320  -4.871  -5.731  1.00 36.64  ? 167 LEU C CD1 1 
ATOM   5813  C  CD2 . LEU C 1 167 ? 20.550  -3.183  -6.107  1.00 41.34  ? 167 LEU C CD2 1 
ATOM   5814  N  N   . VAL C 1 168 ? 19.248  -4.596  -10.505 1.00 29.40  ? 168 VAL C N   1 
ATOM   5815  C  CA  . VAL C 1 168 ? 19.465  -4.863  -11.915 1.00 32.59  ? 168 VAL C CA  1 
ATOM   5816  C  C   . VAL C 1 168 ? 20.838  -5.496  -12.106 1.00 32.63  ? 168 VAL C C   1 
ATOM   5817  O  O   . VAL C 1 168 ? 21.812  -5.068  -11.477 1.00 33.33  ? 168 VAL C O   1 
ATOM   5818  C  CB  . VAL C 1 168 ? 19.368  -3.556  -12.720 1.00 34.33  ? 168 VAL C CB  1 
ATOM   5819  C  CG1 . VAL C 1 168 ? 19.738  -3.740  -14.182 1.00 32.24  ? 168 VAL C CG1 1 
ATOM   5820  C  CG2 . VAL C 1 168 ? 17.957  -2.973  -12.589 1.00 35.37  ? 168 VAL C CG2 1 
ATOM   5821  N  N   . GLY C 1 169 ? 20.888  -6.555  -12.927 1.00 35.60  ? 169 GLY C N   1 
ATOM   5822  C  CA  . GLY C 1 169 ? 22.162  -7.201  -13.249 1.00 40.40  ? 169 GLY C CA  1 
ATOM   5823  C  C   . GLY C 1 169 ? 22.440  -7.250  -14.759 1.00 43.72  ? 169 GLY C C   1 
ATOM   5824  O  O   . GLY C 1 169 ? 22.250  -6.234  -15.464 1.00 43.85  ? 169 GLY C O   1 
ATOM   5825  N  N   . ALA C 1 170 ? 22.826  -8.454  -15.247 1.00 43.28  ? 170 ALA C N   1 
ATOM   5826  C  CA  . ALA C 1 170 ? 23.278  -8.695  -16.631 1.00 48.17  ? 170 ALA C CA  1 
ATOM   5827  C  C   . ALA C 1 170 ? 22.191  -8.465  -17.681 1.00 43.60  ? 170 ALA C C   1 
ATOM   5828  O  O   . ALA C 1 170 ? 22.486  -8.149  -18.829 1.00 51.50  ? 170 ALA C O   1 
ATOM   5829  C  CB  . ALA C 1 170 ? 23.758  -10.117 -16.797 1.00 46.06  ? 170 ALA C CB  1 
ATOM   5830  N  N   . GLU C 1 171 ? 20.932  -8.552  -17.268 1.00 34.04  ? 171 GLU C N   1 
ATOM   5831  C  CA  . GLU C 1 171 ? 19.822  -8.309  -18.150 1.00 34.85  ? 171 GLU C CA  1 
ATOM   5832  C  C   . GLU C 1 171 ? 19.787  -6.862  -18.650 1.00 37.30  ? 171 GLU C C   1 
ATOM   5833  O  O   . GLU C 1 171 ? 19.069  -6.586  -19.625 1.00 37.73  ? 171 GLU C O   1 
ATOM   5834  C  CB  . GLU C 1 171 ? 18.494  -8.784  -17.529 1.00 39.30  ? 171 GLU C CB  1 
ATOM   5835  C  CG  . GLU C 1 171 ? 17.826  -7.875  -16.489 1.00 43.94  ? 171 GLU C CG  1 
ATOM   5836  C  CD  . GLU C 1 171 ? 18.426  -7.832  -15.075 1.00 49.63  ? 171 GLU C CD  1 
ATOM   5837  O  OE1 . GLU C 1 171 ? 19.471  -8.483  -14.845 1.00 43.08  ? 171 GLU C OE1 1 
ATOM   5838  O  OE2 . GLU C 1 171 ? 17.846  -7.142  -14.182 1.00 46.96  ? 171 GLU C OE2 1 
ATOM   5839  N  N   . ASP C 1 172 ? 20.472  -5.914  -17.990 1.00 46.38  ? 172 ASP C N   1 
ATOM   5840  C  CA  . ASP C 1 172 ? 20.415  -4.505  -18.415 1.00 49.16  ? 172 ASP C CA  1 
ATOM   5841  C  C   . ASP C 1 172 ? 21.715  -3.850  -17.982 1.00 50.04  ? 172 ASP C C   1 
ATOM   5842  O  O   . ASP C 1 172 ? 21.742  -2.983  -17.122 1.00 47.93  ? 172 ASP C O   1 
ATOM   5843  C  CB  . ASP C 1 172 ? 19.168  -3.787  -17.914 1.00 43.24  ? 172 ASP C CB  1 
ATOM   5844  C  CG  . ASP C 1 172 ? 18.843  -2.448  -18.539 1.00 40.91  ? 172 ASP C CG  1 
ATOM   5845  O  OD1 . ASP C 1 172 ? 19.570  -2.060  -19.440 1.00 48.13  ? 172 ASP C OD1 1 
ATOM   5846  O  OD2 . ASP C 1 172 ? 17.871  -1.810  -18.115 1.00 44.89  ? 172 ASP C OD2 1 
ATOM   5847  N  N   . PRO C 1 173 ? 22.835  -4.274  -18.602 1.00 49.28  ? 173 PRO C N   1 
ATOM   5848  C  CA  . PRO C 1 173 ? 24.170  -4.111  -17.997 1.00 47.27  ? 173 PRO C CA  1 
ATOM   5849  C  C   . PRO C 1 173 ? 24.621  -2.662  -17.831 1.00 40.46  ? 173 PRO C C   1 
ATOM   5850  O  O   . PRO C 1 173 ? 25.434  -2.349  -16.981 1.00 38.51  ? 173 PRO C O   1 
ATOM   5851  C  CB  . PRO C 1 173 ? 25.121  -4.811  -18.966 1.00 41.28  ? 173 PRO C CB  1 
ATOM   5852  C  CG  . PRO C 1 173 ? 24.220  -5.505  -19.956 1.00 42.61  ? 173 PRO C CG  1 
ATOM   5853  C  CD  . PRO C 1 173 ? 22.841  -4.897  -19.935 1.00 41.91  ? 173 PRO C CD  1 
ATOM   5854  N  N   . ALA C 1 174 ? 24.127  -1.769  -18.692 1.00 33.82  ? 174 ALA C N   1 
ATOM   5855  C  CA  . ALA C 1 174 ? 24.477  -0.372  -18.523 1.00 34.63  ? 174 ALA C CA  1 
ATOM   5856  C  C   . ALA C 1 174 ? 23.949  0.183   -17.194 1.00 39.30  ? 174 ALA C C   1 
ATOM   5857  O  O   . ALA C 1 174 ? 24.388  1.241   -16.781 1.00 36.24  ? 174 ALA C O   1 
ATOM   5858  C  CB  . ALA C 1 174 ? 23.917  0.390   -19.682 1.00 35.76  ? 174 ALA C CB  1 
ATOM   5859  N  N   . PHE C 1 175 ? 22.934  -0.470  -16.580 1.00 43.82  ? 175 PHE C N   1 
ATOM   5860  C  CA  . PHE C 1 175 ? 22.226  0.063   -15.416 1.00 34.38  ? 175 PHE C CA  1 
ATOM   5861  C  C   . PHE C 1 175 ? 22.284  -0.924  -14.273 1.00 32.00  ? 175 PHE C C   1 
ATOM   5862  O  O   . PHE C 1 175 ? 21.574  -0.770  -13.305 1.00 31.50  ? 175 PHE C O   1 
ATOM   5863  C  CB  . PHE C 1 175 ? 20.764  0.362   -15.778 1.00 33.84  ? 175 PHE C CB  1 
ATOM   5864  C  CG  . PHE C 1 175 ? 20.679  1.518   -16.749 1.00 29.45  ? 175 PHE C CG  1 
ATOM   5865  C  CD1 . PHE C 1 175 ? 21.068  2.775   -16.368 1.00 33.14  ? 175 PHE C CD1 1 
ATOM   5866  C  CD2 . PHE C 1 175 ? 20.315  1.313   -18.047 1.00 31.54  ? 175 PHE C CD2 1 
ATOM   5867  C  CE1 . PHE C 1 175 ? 21.053  3.834   -17.253 1.00 31.46  ? 175 PHE C CE1 1 
ATOM   5868  C  CE2 . PHE C 1 175 ? 20.318  2.361   -18.945 1.00 35.14  ? 175 PHE C CE2 1 
ATOM   5869  C  CZ  . PHE C 1 175 ? 20.665  3.624   -18.548 1.00 35.00  ? 175 PHE C CZ  1 
ATOM   5870  N  N   . ALA C 1 176 ? 23.184  -1.910  -14.344 1.00 32.60  ? 176 ALA C N   1 
ATOM   5871  C  CA  . ALA C 1 176 ? 23.410  -2.799  -13.221 1.00 27.02  ? 176 ALA C CA  1 
ATOM   5872  C  C   . ALA C 1 176 ? 23.688  -2.026  -11.949 1.00 26.50  ? 176 ALA C C   1 
ATOM   5873  O  O   . ALA C 1 176 ? 24.332  -0.949  -11.950 1.00 28.40  ? 176 ALA C O   1 
ATOM   5874  C  CB  . ALA C 1 176 ? 24.501  -3.729  -13.569 1.00 28.59  ? 176 ALA C CB  1 
ATOM   5875  N  N   . GLY C 1 177 ? 23.043  -2.521  -10.888 1.00 26.57  ? 177 GLY C N   1 
ATOM   5876  C  CA  . GLY C 1 177 ? 23.170  -1.867  -9.586  1.00 34.26  ? 177 GLY C CA  1 
ATOM   5877  C  C   . GLY C 1 177 ? 22.034  -0.894  -9.233  1.00 27.73  ? 177 GLY C C   1 
ATOM   5878  O  O   . GLY C 1 177 ? 21.979  -0.381  -8.110  1.00 27.44  ? 177 GLY C O   1 
ATOM   5879  N  N   . GLY C 1 178 ? 21.208  -0.600  -10.238 1.00 26.74  ? 178 GLY C N   1 
ATOM   5880  C  CA  . GLY C 1 178 ? 20.008  0.176   -10.055 1.00 27.71  ? 178 GLY C CA  1 
ATOM   5881  C  C   . GLY C 1 178 ? 18.867  -0.707  -9.549  1.00 29.78  ? 178 GLY C C   1 
ATOM   5882  O  O   . GLY C 1 178 ? 19.038  -1.919  -9.306  1.00 24.15  ? 178 GLY C O   1 
ATOM   5883  N  N   . SER C 1 179 ? 17.715  -0.042  -9.311  1.00 29.80  ? 179 SER C N   1 
ATOM   5884  C  CA  . SER C 1 179 ? 16.519  -0.716  -8.865  1.00 23.28  ? 179 SER C CA  1 
ATOM   5885  C  C   . SER C 1 179 ? 15.319  0.103   -9.287  1.00 23.58  ? 179 SER C C   1 
ATOM   5886  O  O   . SER C 1 179 ? 15.447  1.203   -9.738  1.00 24.38  ? 179 SER C O   1 
ATOM   5887  C  CB  . SER C 1 179 ? 16.547  -0.999  -7.416  1.00 23.29  ? 179 SER C CB  1 
ATOM   5888  O  OG  . SER C 1 179 ? 15.498  -1.930  -7.088  1.00 30.58  ? 179 SER C OG  1 
ATOM   5889  N  N   . TYR C 1 180 ? 14.144  -0.502  -9.231  1.00 26.91  ? 180 TYR C N   1 
ATOM   5890  C  CA  . TYR C 1 180 ? 12.923  0.200   -9.555  1.00 25.59  ? 180 TYR C CA  1 
ATOM   5891  C  C   . TYR C 1 180 ? 12.106  0.293   -8.271  1.00 25.07  ? 180 TYR C C   1 
ATOM   5892  O  O   . TYR C 1 180 ? 11.872  -0.723  -7.622  1.00 24.32  ? 180 TYR C O   1 
ATOM   5893  C  CB  . TYR C 1 180 ? 12.122  -0.520  -10.642 1.00 27.03  ? 180 TYR C CB  1 
ATOM   5894  C  CG  . TYR C 1 180 ? 12.793  -0.578  -12.004 1.00 28.46  ? 180 TYR C CG  1 
ATOM   5895  C  CD1 . TYR C 1 180 ? 13.741  -1.575  -12.285 1.00 29.67  ? 180 TYR C CD1 1 
ATOM   5896  C  CD2 . TYR C 1 180 ? 12.485  0.339   -12.982 1.00 26.88  ? 180 TYR C CD2 1 
ATOM   5897  C  CE1 . TYR C 1 180 ? 14.370  -1.629  -13.510 1.00 30.59  ? 180 TYR C CE1 1 
ATOM   5898  C  CE2 . TYR C 1 180 ? 13.104  0.291   -14.215 1.00 30.36  ? 180 TYR C CE2 1 
ATOM   5899  C  CZ  . TYR C 1 180 ? 14.031  -0.707  -14.491 1.00 32.59  ? 180 TYR C CZ  1 
ATOM   5900  O  OH  . TYR C 1 180 ? 14.723  -0.769  -15.689 1.00 29.85  ? 180 TYR C OH  1 
ATOM   5901  N  N   . ALA C 1 181 ? 11.651  1.522   -7.979  1.00 23.86  ? 181 ALA C N   1 
ATOM   5902  C  CA  . ALA C 1 181 ? 10.796  1.789   -6.841  1.00 24.58  ? 181 ALA C CA  1 
ATOM   5903  C  C   . ALA C 1 181 ? 9.408   2.212   -7.260  1.00 22.03  ? 181 ALA C C   1 
ATOM   5904  O  O   . ALA C 1 181 ? 9.245   3.091   -8.105  1.00 22.77  ? 181 ALA C O   1 
ATOM   5905  C  CB  . ALA C 1 181 ? 11.413  2.851   -5.960  1.00 26.08  ? 181 ALA C CB  1 
ATOM   5906  N  N   . VAL C 1 182 ? 8.421   1.609   -6.587  1.00 25.46  ? 182 VAL C N   1 
ATOM   5907  C  CA  . VAL C 1 182 ? 7.017   1.962   -6.719  1.00 24.55  ? 182 VAL C CA  1 
ATOM   5908  C  C   . VAL C 1 182 ? 6.537   2.509   -5.397  1.00 22.75  ? 182 VAL C C   1 
ATOM   5909  O  O   . VAL C 1 182 ? 6.738   1.848   -4.395  1.00 22.07  ? 182 VAL C O   1 
ATOM   5910  C  CB  . VAL C 1 182 ? 6.134   0.767   -7.116  1.00 27.67  ? 182 VAL C CB  1 
ATOM   5911  C  CG1 . VAL C 1 182 ? 4.640   1.143   -7.100  1.00 25.25  ? 182 VAL C CG1 1 
ATOM   5912  C  CG2 . VAL C 1 182 ? 6.576   0.163   -8.469  1.00 32.85  ? 182 VAL C CG2 1 
ATOM   5913  N  N   . VAL C 1 183 ? 5.902   3.695   -5.422  1.00 22.35  ? 183 VAL C N   1 
ATOM   5914  C  CA  . VAL C 1 183 ? 5.387   4.311   -4.210  1.00 22.20  ? 183 VAL C CA  1 
ATOM   5915  C  C   . VAL C 1 183 ? 3.906   4.465   -4.346  1.00 21.05  ? 183 VAL C C   1 
ATOM   5916  O  O   . VAL C 1 183 ? 3.461   4.806   -5.420  1.00 24.42  ? 183 VAL C O   1 
ATOM   5917  C  CB  . VAL C 1 183 ? 5.988   5.651   -3.803  1.00 22.74  ? 183 VAL C CB  1 
ATOM   5918  C  CG1 . VAL C 1 183 ? 7.465   5.492   -3.576  1.00 24.86  ? 183 VAL C CG1 1 
ATOM   5919  C  CG2 . VAL C 1 183 ? 5.753   6.712   -4.836  1.00 24.34  ? 183 VAL C CG2 1 
ATOM   5920  N  N   . GLN C 1 184 ? 3.181   4.145   -3.278  1.00 20.41  ? 184 GLN C N   1 
ATOM   5921  C  CA  . GLN C 1 184 ? 1.763   4.496   -3.169  1.00 20.22  ? 184 GLN C CA  1 
ATOM   5922  C  C   . GLN C 1 184 ? 1.460   4.926   -1.729  1.00 20.57  ? 184 GLN C C   1 
ATOM   5923  O  O   . GLN C 1 184 ? 1.795   4.222   -0.776  1.00 21.86  ? 184 GLN C O   1 
ATOM   5924  C  CB  . GLN C 1 184 ? 0.897   3.277   -3.452  1.00 22.79  ? 184 GLN C CB  1 
ATOM   5925  C  CG  . GLN C 1 184 ? 0.951   2.677   -4.856  1.00 21.61  ? 184 GLN C CG  1 
ATOM   5926  C  CD  . GLN C 1 184 ? 0.011   1.486   -4.895  1.00 24.04  ? 184 GLN C CD  1 
ATOM   5927  O  OE1 . GLN C 1 184 ? 0.238   0.435   -4.234  1.00 23.32  ? 184 GLN C OE1 1 
ATOM   5928  N  NE2 . GLN C 1 184 ? -1.114  1.728   -5.556  1.00 22.37  ? 184 GLN C NE2 1 
ATOM   5929  N  N   . LYS C 1 185 ? 0.900   6.126   -1.561  1.00 19.16  ? 185 LYS C N   1 
ATOM   5930  C  CA  . LYS C 1 185 ? 0.409   6.537   -0.270  1.00 21.76  ? 185 LYS C CA  1 
ATOM   5931  C  C   . LYS C 1 185 ? -1.010  5.999   -0.033  1.00 25.50  ? 185 LYS C C   1 
ATOM   5932  O  O   . LYS C 1 185 ? -1.908  6.269   -0.845  1.00 22.46  ? 185 LYS C O   1 
ATOM   5933  C  CB  . LYS C 1 185 ? 0.384   8.065   -0.259  1.00 23.26  ? 185 LYS C CB  1 
ATOM   5934  C  CG  . LYS C 1 185 ? -0.072  8.587   1.089   1.00 24.39  ? 185 LYS C CG  1 
ATOM   5935  C  CD  . LYS C 1 185 ? 0.371   9.993   1.423   1.00 25.42  ? 185 LYS C CD  1 
ATOM   5936  C  CE  . LYS C 1 185 ? -0.305  10.909  0.506   1.00 28.29  ? 185 LYS C CE  1 
ATOM   5937  N  NZ  . LYS C 1 185 ? 0.127   12.180  1.046   1.00 29.71  ? 185 LYS C NZ  1 
ATOM   5938  N  N   . TYR C 1 186 ? -1.204  5.245   1.071   1.00 22.44  ? 186 TYR C N   1 
ATOM   5939  C  CA  . TYR C 1 186 ? -2.493  4.649   1.379   1.00 21.47  ? 186 TYR C CA  1 
ATOM   5940  C  C   . TYR C 1 186 ? -3.067  5.284   2.640   1.00 26.45  ? 186 TYR C C   1 
ATOM   5941  O  O   . TYR C 1 186 ? -2.311  5.529   3.585   1.00 28.35  ? 186 TYR C O   1 
ATOM   5942  C  CB  . TYR C 1 186 ? -2.405  3.161   1.619   1.00 20.93  ? 186 TYR C CB  1 
ATOM   5943  C  CG  . TYR C 1 186 ? -2.302  2.283   0.374   1.00 24.69  ? 186 TYR C CG  1 
ATOM   5944  C  CD1 . TYR C 1 186 ? -1.068  1.960   -0.158  1.00 25.05  ? 186 TYR C CD1 1 
ATOM   5945  C  CD2 . TYR C 1 186 ? -3.431  1.772   -0.276  1.00 26.32  ? 186 TYR C CD2 1 
ATOM   5946  C  CE1 . TYR C 1 186 ? -0.948  1.142   -1.270  1.00 28.83  ? 186 TYR C CE1 1 
ATOM   5947  C  CE2 . TYR C 1 186 ? -3.310  0.951   -1.380  1.00 23.74  ? 186 TYR C CE2 1 
ATOM   5948  C  CZ  . TYR C 1 186 ? -2.075  0.618   -1.886  1.00 25.16  ? 186 TYR C CZ  1 
ATOM   5949  O  OH  . TYR C 1 186 ? -1.861  -0.170  -2.998  1.00 23.13  ? 186 TYR C OH  1 
ATOM   5950  N  N   . LEU C 1 187 ? -4.378  5.563   2.628   1.00 25.36  ? 187 LEU C N   1 
ATOM   5951  C  CA  . LEU C 1 187 ? -5.093  6.024   3.811   1.00 27.72  ? 187 LEU C CA  1 
ATOM   5952  C  C   . LEU C 1 187 ? -6.080  4.942   4.239   1.00 30.09  ? 187 LEU C C   1 
ATOM   5953  O  O   . LEU C 1 187 ? -6.748  4.319   3.413   1.00 25.97  ? 187 LEU C O   1 
ATOM   5954  C  CB  . LEU C 1 187 ? -5.827  7.319   3.523   1.00 27.03  ? 187 LEU C CB  1 
ATOM   5955  C  CG  . LEU C 1 187 ? -4.968  8.547   3.245   1.00 30.98  ? 187 LEU C CG  1 
ATOM   5956  C  CD1 . LEU C 1 187 ? -5.861  9.743   2.870   1.00 30.70  ? 187 LEU C CD1 1 
ATOM   5957  C  CD2 . LEU C 1 187 ? -4.176  8.910   4.512   1.00 32.10  ? 187 LEU C CD2 1 
ATOM   5958  N  N   . HIS C 1 188 ? -6.152  4.715   5.546   1.00 23.91  ? 188 HIS C N   1 
ATOM   5959  C  CA  . HIS C 1 188 ? -6.929  3.616   6.053   1.00 22.25  ? 188 HIS C CA  1 
ATOM   5960  C  C   . HIS C 1 188 ? -8.222  4.111   6.675   1.00 23.87  ? 188 HIS C C   1 
ATOM   5961  O  O   . HIS C 1 188 ? -8.277  5.195   7.210   1.00 24.52  ? 188 HIS C O   1 
ATOM   5962  C  CB  . HIS C 1 188 ? -6.132  2.851   7.126   1.00 21.66  ? 188 HIS C CB  1 
ATOM   5963  C  CG  . HIS C 1 188 ? -4.991  2.124   6.545   1.00 22.78  ? 188 HIS C CG  1 
ATOM   5964  N  ND1 . HIS C 1 188 ? -5.125  1.103   5.625   1.00 21.10  ? 188 HIS C ND1 1 
ATOM   5965  C  CD2 . HIS C 1 188 ? -3.658  2.293   6.736   1.00 25.40  ? 188 HIS C CD2 1 
ATOM   5966  C  CE1 . HIS C 1 188 ? -3.920  0.683   5.276   1.00 22.35  ? 188 HIS C CE1 1 
ATOM   5967  N  NE2 . HIS C 1 188 ? -3.002  1.374   5.954   1.00 22.76  ? 188 HIS C NE2 1 
ATOM   5968  N  N   . ASP C 1 189 ? -9.234  3.253   6.647   1.00 24.94  ? 189 ASP C N   1 
ATOM   5969  C  CA  . ASP C 1 189 ? -10.491 3.467   7.355   1.00 29.20  ? 189 ASP C CA  1 
ATOM   5970  C  C   . ASP C 1 189 ? -10.423 2.639   8.636   1.00 27.66  ? 189 ASP C C   1 
ATOM   5971  O  O   . ASP C 1 189 ? -10.797 1.441   8.659   1.00 25.53  ? 189 ASP C O   1 
ATOM   5972  C  CB  . ASP C 1 189 ? -11.706 3.129   6.497   1.00 27.93  ? 189 ASP C CB  1 
ATOM   5973  C  CG  . ASP C 1 189 ? -13.070 3.367   7.136   1.00 26.50  ? 189 ASP C CG  1 
ATOM   5974  O  OD1 . ASP C 1 189 ? -13.156 3.754   8.329   1.00 26.28  ? 189 ASP C OD1 1 
ATOM   5975  O  OD2 . ASP C 1 189 ? -14.029 3.133   6.403   1.00 34.11  ? 189 ASP C OD2 1 
ATOM   5976  N  N   . ILE C 1 190 ? -9.907  3.311   9.662   1.00 24.09  ? 190 ILE C N   1 
ATOM   5977  C  CA  . ILE C 1 190 ? -9.631  2.699   10.948  1.00 25.13  ? 190 ILE C CA  1 
ATOM   5978  C  C   . ILE C 1 190 ? -10.936 2.342   11.665  1.00 27.04  ? 190 ILE C C   1 
ATOM   5979  O  O   . ILE C 1 190 ? -10.982 1.277   12.273  1.00 24.90  ? 190 ILE C O   1 
ATOM   5980  C  CB  . ILE C 1 190 ? -8.703  3.619   11.752  1.00 27.08  ? 190 ILE C CB  1 
ATOM   5981  C  CG1 . ILE C 1 190 ? -7.294  3.604   11.176  1.00 29.87  ? 190 ILE C CG1 1 
ATOM   5982  C  CG2 . ILE C 1 190 ? -8.679  3.201   13.191  1.00 30.65  ? 190 ILE C CG2 1 
ATOM   5983  C  CD1 . ILE C 1 190 ? -6.613  2.240   11.276  1.00 28.92  ? 190 ILE C CD1 1 
ATOM   5984  N  N   . ASP C 1 191 ? -12.006 3.126   11.478  1.00 30.17  ? 191 ASP C N   1 
ATOM   5985  C  CA  . ASP C 1 191 ? -13.291 2.836   12.136  1.00 31.96  ? 191 ASP C CA  1 
ATOM   5986  C  C   . ASP C 1 191 ? -13.840 1.519   11.608  1.00 27.36  ? 191 ASP C C   1 
ATOM   5987  O  O   . ASP C 1 191 ? -14.163 0.618   12.337  1.00 31.68  ? 191 ASP C O   1 
ATOM   5988  C  CB  . ASP C 1 191 ? -14.361 3.888   11.915  1.00 31.99  ? 191 ASP C CB  1 
ATOM   5989  C  CG  . ASP C 1 191 ? -13.983 5.300   12.312  1.00 42.47  ? 191 ASP C CG  1 
ATOM   5990  O  OD1 . ASP C 1 191 ? -13.245 5.394   13.302  1.00 42.35  ? 191 ASP C OD1 1 
ATOM   5991  O  OD2 . ASP C 1 191 ? -14.386 6.276   11.604  1.00 61.22  ? 191 ASP C OD2 1 
ATOM   5992  N  N   . ALA C 1 192 ? -13.839 1.348   10.315  1.00 22.87  ? 192 ALA C N   1 
ATOM   5993  C  CA  . ALA C 1 192 ? -14.287 0.097   9.744   1.00 21.25  ? 192 ALA C CA  1 
ATOM   5994  C  C   . ALA C 1 192 ? -13.433 -1.056  10.221  1.00 22.86  ? 192 ALA C C   1 
ATOM   5995  O  O   . ALA C 1 192 ? -13.922 -2.126  10.460  1.00 25.40  ? 192 ALA C O   1 
ATOM   5996  C  CB  . ALA C 1 192 ? -14.255 0.182   8.213   1.00 18.68  ? 192 ALA C CB  1 
ATOM   5997  N  N   . TRP C 1 193 ? -12.118 -0.887  10.193  1.00 26.62  ? 193 TRP C N   1 
ATOM   5998  C  CA  . TRP C 1 193 ? -11.175 -1.941  10.503  1.00 25.12  ? 193 TRP C CA  1 
ATOM   5999  C  C   . TRP C 1 193 ? -11.317 -2.405  11.945  1.00 24.28  ? 193 TRP C C   1 
ATOM   6000  O  O   . TRP C 1 193 ? -11.295 -3.612  12.208  1.00 23.14  ? 193 TRP C O   1 
ATOM   6001  C  CB  . TRP C 1 193 ? -9.764  -1.402  10.244  1.00 24.63  ? 193 TRP C CB  1 
ATOM   6002  C  CG  . TRP C 1 193 ? -8.676  -2.384  10.541  1.00 21.95  ? 193 TRP C CG  1 
ATOM   6003  C  CD1 . TRP C 1 193 ? -7.762  -2.303  11.540  1.00 22.23  ? 193 TRP C CD1 1 
ATOM   6004  C  CD2 . TRP C 1 193 ? -8.375  -3.582  9.796   1.00 20.28  ? 193 TRP C CD2 1 
ATOM   6005  N  NE1 . TRP C 1 193 ? -6.885  -3.355  11.434  1.00 22.56  ? 193 TRP C NE1 1 
ATOM   6006  C  CE2 . TRP C 1 193 ? -7.255  -4.163  10.396  1.00 22.74  ? 193 TRP C CE2 1 
ATOM   6007  C  CE3 . TRP C 1 193 ? -8.931  -4.205  8.706   1.00 19.08  ? 193 TRP C CE3 1 
ATOM   6008  C  CZ2 . TRP C 1 193 ? -6.665  -5.322  9.924   1.00 22.75  ? 193 TRP C CZ2 1 
ATOM   6009  C  CZ3 . TRP C 1 193 ? -8.337  -5.329  8.233   1.00 19.56  ? 193 TRP C CZ3 1 
ATOM   6010  C  CH2 . TRP C 1 193 ? -7.223  -5.885  8.824   1.00 20.56  ? 193 TRP C CH2 1 
ATOM   6011  N  N   . GLU C 1 194 ? -11.514 -1.443  12.852  1.00 23.68  ? 194 GLU C N   1 
ATOM   6012  C  CA  . GLU C 1 194 ? -11.660 -1.737  14.262  1.00 25.37  ? 194 GLU C CA  1 
ATOM   6013  C  C   . GLU C 1 194 ? -13.032 -2.321  14.572  1.00 29.90  ? 194 GLU C C   1 
ATOM   6014  O  O   . GLU C 1 194 ? -13.261 -2.895  15.628  1.00 32.70  ? 194 GLU C O   1 
ATOM   6015  C  CB  . GLU C 1 194 ? -11.234 -0.528  15.086  1.00 28.28  ? 194 GLU C CB  1 
ATOM   6016  C  CG  . GLU C 1 194 ? -9.775  -0.787  15.474  1.00 44.89  ? 194 GLU C CG  1 
ATOM   6017  C  CD  . GLU C 1 194 ? -8.908  0.372   15.821  1.00 51.67  ? 194 GLU C CD  1 
ATOM   6018  O  OE1 . GLU C 1 194 ? -9.513  1.390   16.226  1.00 49.71  ? 194 GLU C OE1 1 
ATOM   6019  O  OE2 . GLU C 1 194 ? -7.677  0.237   15.594  1.00 54.94  ? 194 GLU C OE2 1 
ATOM   6020  N  N   . GLY C 1 195 ? -13.948 -2.332  13.620  1.00 29.61  ? 195 GLY C N   1 
ATOM   6021  C  CA  . GLY C 1 195 ? -15.193 -3.015  13.896  1.00 29.92  ? 195 GLY C CA  1 
ATOM   6022  C  C   . GLY C 1 195 ? -15.098 -4.479  13.580  1.00 29.64  ? 195 GLY C C   1 
ATOM   6023  O  O   . GLY C 1 195 ? -16.106 -5.154  13.723  1.00 32.16  ? 195 GLY C O   1 
ATOM   6024  N  N   . LEU C 1 196 ? -13.986 -4.929  12.999  1.00 27.09  ? 196 LEU C N   1 
ATOM   6025  C  CA  . LEU C 1 196 ? -13.813 -6.348  12.739  1.00 27.88  ? 196 LEU C CA  1 
ATOM   6026  C  C   . LEU C 1 196 ? -13.269 -7.004  13.982  1.00 24.60  ? 196 LEU C C   1 
ATOM   6027  O  O   . LEU C 1 196 ? -12.568 -6.367  14.734  1.00 24.06  ? 196 LEU C O   1 
ATOM   6028  C  CB  . LEU C 1 196 ? -12.860 -6.600  11.575  1.00 34.78  ? 196 LEU C CB  1 
ATOM   6029  C  CG  . LEU C 1 196 ? -13.438 -6.815  10.179  1.00 32.92  ? 196 LEU C CG  1 
ATOM   6030  C  CD1 . LEU C 1 196 ? -14.559 -5.885  9.971   1.00 37.00  ? 196 LEU C CD1 1 
ATOM   6031  C  CD2 . LEU C 1 196 ? -12.343 -6.590  9.156   1.00 31.21  ? 196 LEU C CD2 1 
ATOM   6032  N  N   . SER C 1 197 ? -13.634 -8.271  14.184  1.00 25.43  ? 197 SER C N   1 
ATOM   6033  C  CA  . SER C 1 197 ? -12.971 -9.094  15.170  1.00 27.60  ? 197 SER C CA  1 
ATOM   6034  C  C   . SER C 1 197 ? -11.517 -9.351  14.720  1.00 28.58  ? 197 SER C C   1 
ATOM   6035  O  O   . SER C 1 197 ? -11.188 -9.287  13.531  1.00 25.09  ? 197 SER C O   1 
ATOM   6036  C  CB  . SER C 1 197 ? -13.672 -10.418 15.331  1.00 27.33  ? 197 SER C CB  1 
ATOM   6037  O  OG  . SER C 1 197 ? -13.409 -11.256 14.208  1.00 24.60  ? 197 SER C OG  1 
ATOM   6038  N  N   . VAL C 1 198 ? -10.667 -9.688  15.695  1.00 25.76  ? 198 VAL C N   1 
ATOM   6039  C  CA  . VAL C 1 198 ? -9.308  -10.024 15.391  1.00 26.44  ? 198 VAL C CA  1 
ATOM   6040  C  C   . VAL C 1 198 ? -9.255  -11.196 14.392  1.00 27.14  ? 198 VAL C C   1 
ATOM   6041  O  O   . VAL C 1 198 ? -8.439  -11.168 13.479  1.00 26.43  ? 198 VAL C O   1 
ATOM   6042  C  CB  . VAL C 1 198 ? -8.477  -10.260 16.659  1.00 26.68  ? 198 VAL C CB  1 
ATOM   6043  C  CG1 . VAL C 1 198 ? -7.103  -10.836 16.270  1.00 31.33  ? 198 VAL C CG1 1 
ATOM   6044  C  CG2 . VAL C 1 198 ? -8.346  -9.014  17.499  1.00 24.15  ? 198 VAL C CG2 1 
ATOM   6045  N  N   . GLU C 1 199 ? -10.118 -12.200 14.518  1.00 29.25  ? 199 GLU C N   1 
ATOM   6046  C  CA  . GLU C 1 199 ? -10.042 -13.387 13.659  1.00 34.71  ? 199 GLU C CA  1 
ATOM   6047  C  C   . GLU C 1 199 ? -10.390 -12.929 12.233  1.00 30.12  ? 199 GLU C C   1 
ATOM   6048  O  O   . GLU C 1 199 ? -9.733  -13.365 11.304  1.00 33.61  ? 199 GLU C O   1 
ATOM   6049  C  CB  . GLU C 1 199 ? -10.834 -14.646 14.106  1.00 42.14  ? 199 GLU C CB  1 
ATOM   6050  C  CG  . GLU C 1 199 ? -10.806 -15.084 15.593  1.00 55.91  ? 199 GLU C CG  1 
ATOM   6051  C  CD  . GLU C 1 199 ? -10.692 -14.144 16.867  1.00 63.75  ? 199 GLU C CD  1 
ATOM   6052  O  OE1 . GLU C 1 199 ? -9.683  -14.479 17.706  1.00 39.00  ? 199 GLU C OE1 1 
ATOM   6053  O  OE2 . GLU C 1 199 ? -11.550 -13.114 17.045  1.00 40.21  ? 199 GLU C OE2 1 
ATOM   6054  N  N   . ALA C 1 200 ? -11.347 -12.000 12.062  1.00 24.74  ? 200 ALA C N   1 
ATOM   6055  C  CA  . ALA C 1 200 ? -11.706 -11.484 10.749  1.00 27.23  ? 200 ALA C CA  1 
ATOM   6056  C  C   . ALA C 1 200 ? -10.563 -10.673 10.108  1.00 31.08  ? 200 ALA C C   1 
ATOM   6057  O  O   . ALA C 1 200 ? -10.398 -10.639 8.878   1.00 34.59  ? 200 ALA C O   1 
ATOM   6058  C  CB  . ALA C 1 200 ? -12.903 -10.557 10.871  1.00 27.51  ? 200 ALA C CB  1 
ATOM   6059  N  N   . GLN C 1 201 ? -9.848  -9.899  10.937  1.00 28.64  ? 201 GLN C N   1 
ATOM   6060  C  CA  . GLN C 1 201 ? -8.701  -9.159  10.445  1.00 26.14  ? 201 GLN C CA  1 
ATOM   6061  C  C   . GLN C 1 201 ? -7.617  -10.129 9.982   1.00 24.28  ? 201 GLN C C   1 
ATOM   6062  O  O   . GLN C 1 201 ? -6.960  -9.891  9.003   1.00 25.29  ? 201 GLN C O   1 
ATOM   6063  C  CB  . GLN C 1 201 ? -8.150  -8.288  11.558  1.00 25.39  ? 201 GLN C CB  1 
ATOM   6064  C  CG  . GLN C 1 201 ? -9.072  -7.116  11.862  1.00 23.59  ? 201 GLN C CG  1 
ATOM   6065  C  CD  . GLN C 1 201 ? -8.501  -6.296  12.978  1.00 23.99  ? 201 GLN C CD  1 
ATOM   6066  O  OE1 . GLN C 1 201 ? -7.483  -6.632  13.587  1.00 31.52  ? 201 GLN C OE1 1 
ATOM   6067  N  NE2 . GLN C 1 201 ? -9.138  -5.187  13.227  1.00 23.89  ? 201 GLN C NE2 1 
ATOM   6068  N  N   . GLU C 1 202 ? -7.437  -11.239 10.689  1.00 20.99  ? 202 GLU C N   1 
ATOM   6069  C  CA  . GLU C 1 202 ? -6.405  -12.176 10.337  1.00 23.28  ? 202 GLU C CA  1 
ATOM   6070  C  C   . GLU C 1 202 ? -6.732  -12.781 8.980   1.00 27.92  ? 202 GLU C C   1 
ATOM   6071  O  O   . GLU C 1 202 ? -5.829  -13.118 8.218   1.00 23.56  ? 202 GLU C O   1 
ATOM   6072  C  CB  . GLU C 1 202 ? -6.237  -13.257 11.399  1.00 25.49  ? 202 GLU C CB  1 
ATOM   6073  C  CG  . GLU C 1 202 ? -5.584  -12.729 12.677  1.00 28.87  ? 202 GLU C CG  1 
ATOM   6074  C  CD  . GLU C 1 202 ? -5.654  -13.674 13.877  1.00 29.96  ? 202 GLU C CD  1 
ATOM   6075  O  OE1 . GLU C 1 202 ? -6.469  -14.612 13.775  1.00 33.39  ? 202 GLU C OE1 1 
ATOM   6076  O  OE2 . GLU C 1 202 ? -4.897  -13.486 14.865  1.00 31.18  ? 202 GLU C OE2 1 
ATOM   6077  N  N   . ARG C 1 203 ? -8.029  -12.908 8.697   1.00 29.40  ? 203 ARG C N   1 
ATOM   6078  C  CA  . ARG C 1 203 ? -8.504  -13.458 7.450   1.00 31.85  ? 203 ARG C CA  1 
ATOM   6079  C  C   . ARG C 1 203 ? -8.261  -12.458 6.314   1.00 29.58  ? 203 ARG C C   1 
ATOM   6080  O  O   . ARG C 1 203 ? -8.017  -12.906 5.173   1.00 26.44  ? 203 ARG C O   1 
ATOM   6081  C  CB  . ARG C 1 203 ? -9.987  -13.842 7.528   1.00 31.68  ? 203 ARG C CB  1 
ATOM   6082  C  CG  . ARG C 1 203 ? -10.290 -15.229 8.076   1.00 36.13  ? 203 ARG C CG  1 
ATOM   6083  C  CD  . ARG C 1 203 ? -11.827 -15.493 8.012   1.00 43.32  ? 203 ARG C CD  1 
ATOM   6084  N  NE  . ARG C 1 203 ? -12.546 -15.351 9.294   1.00 54.70  ? 203 ARG C NE  1 
ATOM   6085  C  CZ  . ARG C 1 203 ? -12.299 -16.116 10.414  1.00 75.62  ? 203 ARG C CZ  1 
ATOM   6086  N  NH1 . ARG C 1 203 ? -12.952 -15.895 11.553  1.00 61.06  ? 203 ARG C NH1 1 
ATOM   6087  N  NH2 . ARG C 1 203 ? -11.374 -17.088 10.429  1.00 86.88  ? 203 ARG C NH2 1 
ATOM   6088  N  N   . VAL C 1 204 ? -8.346  -11.145 6.595   1.00 22.32  ? 204 VAL C N   1 
ATOM   6089  C  CA  . VAL C 1 204 ? -7.970  -10.161 5.575   1.00 24.42  ? 204 VAL C CA  1 
ATOM   6090  C  C   . VAL C 1 204 ? -6.455  -10.209 5.227   1.00 28.16  ? 204 VAL C C   1 
ATOM   6091  O  O   . VAL C 1 204 ? -6.057  -10.156 4.047   1.00 23.02  ? 204 VAL C O   1 
ATOM   6092  C  CB  . VAL C 1 204 ? -8.387  -8.778  6.066   1.00 22.98  ? 204 VAL C CB  1 
ATOM   6093  C  CG1 . VAL C 1 204 ? -7.837  -7.657  5.181   1.00 24.06  ? 204 VAL C CG1 1 
ATOM   6094  C  CG2 . VAL C 1 204 ? -9.893  -8.699  6.171   1.00 24.43  ? 204 VAL C CG2 1 
ATOM   6095  N  N   . ILE C 1 205 ? -5.589  -10.341 6.253   1.00 24.71  ? 205 ILE C N   1 
ATOM   6096  C  CA  . ILE C 1 205 ? -4.167  -10.227 6.069   1.00 22.63  ? 205 ILE C CA  1 
ATOM   6097  C  C   . ILE C 1 205 ? -3.594  -11.556 5.653   1.00 24.34  ? 205 ILE C C   1 
ATOM   6098  O  O   . ILE C 1 205 ? -2.802  -11.595 4.723   1.00 28.74  ? 205 ILE C O   1 
ATOM   6099  C  CB  . ILE C 1 205 ? -3.489  -9.701  7.333   1.00 23.89  ? 205 ILE C CB  1 
ATOM   6100  C  CG1 . ILE C 1 205 ? -4.037  -8.309  7.715   1.00 22.77  ? 205 ILE C CG1 1 
ATOM   6101  C  CG2 . ILE C 1 205 ? -1.957  -9.690  7.154   1.00 27.75  ? 205 ILE C CG2 1 
ATOM   6102  C  CD1 . ILE C 1 205 ? -3.722  -7.242  6.688   1.00 21.92  ? 205 ILE C CD1 1 
ATOM   6103  N  N   . GLY C 1 206 ? -3.938  -12.618 6.362   1.00 24.66  ? 206 GLY C N   1 
ATOM   6104  C  CA  . GLY C 1 206 ? -3.399  -13.927 6.046   1.00 26.33  ? 206 GLY C CA  1 
ATOM   6105  C  C   . GLY C 1 206 ? -2.374  -14.404 7.077   1.00 29.52  ? 206 GLY C C   1 
ATOM   6106  O  O   . GLY C 1 206 ? -1.736  -15.434 6.837   1.00 26.92  ? 206 GLY C O   1 
ATOM   6107  N  N   . ARG C 1 207 ? -2.240  -13.693 8.218   1.00 26.78  ? 207 ARG C N   1 
ATOM   6108  C  CA  . ARG C 1 207 ? -1.358  -14.113 9.279   1.00 25.29  ? 207 ARG C CA  1 
ATOM   6109  C  C   . ARG C 1 207 ? -2.021  -13.779 10.605  1.00 26.66  ? 207 ARG C C   1 
ATOM   6110  O  O   . ARG C 1 207 ? -2.930  -12.956 10.629  1.00 25.55  ? 207 ARG C O   1 
ATOM   6111  C  CB  . ARG C 1 207 ? -0.002  -13.413 9.293   1.00 26.53  ? 207 ARG C CB  1 
ATOM   6112  C  CG  . ARG C 1 207 ? 0.618   -13.224 7.913   1.00 28.11  ? 207 ARG C CG  1 
ATOM   6113  C  CD  . ARG C 1 207 ? 1.882   -12.371 7.835   1.00 27.06  ? 207 ARG C CD  1 
ATOM   6114  N  NE  . ARG C 1 207 ? 2.943   -13.027 8.603   1.00 24.72  ? 207 ARG C NE  1 
ATOM   6115  C  CZ  . ARG C 1 207 ? 3.735   -13.989 8.153   1.00 27.82  ? 207 ARG C CZ  1 
ATOM   6116  N  NH1 . ARG C 1 207 ? 3.723   -14.362 6.869   1.00 25.74  ? 207 ARG C NH1 1 
ATOM   6117  N  NH2 . ARG C 1 207 ? 4.573   -14.540 9.022   1.00 31.74  ? 207 ARG C NH2 1 
ATOM   6118  N  N   . ARG C 1 208 ? -1.475  -14.347 11.702  1.00 25.84  ? 208 ARG C N   1 
ATOM   6119  C  CA  . ARG C 1 208 ? -1.981  -14.118 13.058  1.00 28.61  ? 208 ARG C CA  1 
ATOM   6120  C  C   . ARG C 1 208 ? -1.567  -12.722 13.529  1.00 25.08  ? 208 ARG C C   1 
ATOM   6121  O  O   . ARG C 1 208 ? -0.478  -12.279 13.258  1.00 28.06  ? 208 ARG C O   1 
ATOM   6122  C  CB  . ARG C 1 208 ? -1.455  -15.154 14.080  1.00 31.50  ? 208 ARG C CB  1 
ATOM   6123  C  CG  . ARG C 1 208 ? -1.737  -16.631 13.771  1.00 34.10  ? 208 ARG C CG  1 
ATOM   6124  C  CD  . ARG C 1 208 ? -3.205  -16.922 13.613  1.00 41.72  ? 208 ARG C CD  1 
ATOM   6125  N  NE  . ARG C 1 208 ? -3.910  -16.627 14.870  1.00 62.04  ? 208 ARG C NE  1 
ATOM   6126  C  CZ  . ARG C 1 208 ? -3.732  -17.292 16.015  1.00 64.92  ? 208 ARG C CZ  1 
ATOM   6127  N  NH1 . ARG C 1 208 ? -3.008  -18.405 16.029  1.00 69.45  ? 208 ARG C NH1 1 
ATOM   6128  N  NH2 . ARG C 1 208 ? -4.281  -16.827 17.123  1.00 61.03  ? 208 ARG C NH2 1 
ATOM   6129  N  N   . LYS C 1 209 ? -2.400  -12.046 14.282  1.00 25.63  ? 209 LYS C N   1 
ATOM   6130  C  CA  . LYS C 1 209 ? -2.146  -10.666 14.589  1.00 23.83  ? 209 LYS C CA  1 
ATOM   6131  C  C   . LYS C 1 209 ? -1.097  -10.523 15.684  1.00 25.58  ? 209 LYS C C   1 
ATOM   6132  O  O   . LYS C 1 209 ? -0.125  -9.799  15.484  1.00 26.71  ? 209 LYS C O   1 
ATOM   6133  C  CB  . LYS C 1 209 ? -3.436  -9.941  14.934  1.00 25.78  ? 209 LYS C CB  1 
ATOM   6134  C  CG  . LYS C 1 209 ? -3.246  -8.450  15.147  1.00 26.73  ? 209 LYS C CG  1 
ATOM   6135  C  CD  . LYS C 1 209 ? -4.576  -7.711  15.274  1.00 27.34  ? 209 LYS C CD  1 
ATOM   6136  C  CE  . LYS C 1 209 ? -4.356  -6.262  15.062  1.00 27.34  ? 209 LYS C CE  1 
ATOM   6137  N  NZ  . LYS C 1 209 ? -5.600  -5.535  15.286  1.00 28.31  ? 209 LYS C NZ  1 
ATOM   6138  N  N   . MET C 1 210 ? -1.259  -11.214 16.811  1.00 29.62  ? 210 MET C N   1 
ATOM   6139  C  CA  . MET C 1 210 ? -0.338  -11.040 17.952  1.00 34.66  ? 210 MET C CA  1 
ATOM   6140  C  C   . MET C 1 210 ? 0.990   -11.724 17.629  1.00 32.78  ? 210 MET C C   1 
ATOM   6141  O  O   . MET C 1 210 ? 2.014   -11.063 17.704  1.00 30.78  ? 210 MET C O   1 
ATOM   6142  C  CB  . MET C 1 210 ? -0.874  -11.458 19.344  1.00 37.51  ? 210 MET C CB  1 
ATOM   6143  C  CG  . MET C 1 210 ? -2.131  -10.651 19.845  1.00 51.00  ? 210 MET C CG  1 
ATOM   6144  S  SD  . MET C 1 210 ? -2.284  -8.832  19.796  1.00 60.23  ? 210 MET C SD  1 
ATOM   6145  C  CE  . MET C 1 210 ? -3.991  -8.542  19.302  1.00 49.98  ? 210 MET C CE  1 
ATOM   6146  N  N   . THR C 1 211 ? 0.991   -12.988 17.148  1.00 32.99  ? 211 THR C N   1 
ATOM   6147  C  CA  . THR C 1 211 ? 2.233   -13.759 16.999  1.00 32.43  ? 211 THR C CA  1 
ATOM   6148  C  C   . THR C 1 211 ? 2.839   -13.686 15.603  1.00 30.52  ? 211 THR C C   1 
ATOM   6149  O  O   . THR C 1 211 ? 3.939   -14.192 15.429  1.00 32.22  ? 211 THR C O   1 
ATOM   6150  C  CB  . THR C 1 211 ? 1.958   -15.219 17.334  1.00 34.49  ? 211 THR C CB  1 
ATOM   6151  O  OG1 . THR C 1 211 ? 0.986   -15.705 16.402  1.00 32.33  ? 211 THR C OG1 1 
ATOM   6152  C  CG2 . THR C 1 211 ? 1.428   -15.299 18.752  1.00 38.15  ? 211 THR C CG2 1 
ATOM   6153  N  N   . ASP C 1 212 ? 2.114   -13.149 14.601  1.00 27.40  ? 212 ASP C N   1 
ATOM   6154  C  CA  . ASP C 1 212 ? 2.633   -13.011 13.239  1.00 26.81  ? 212 ASP C CA  1 
ATOM   6155  C  C   . ASP C 1 212 ? 2.967   -14.345 12.559  1.00 24.44  ? 212 ASP C C   1 
ATOM   6156  O  O   . ASP C 1 212 ? 3.712   -14.396 11.591  1.00 23.22  ? 212 ASP C O   1 
ATOM   6157  C  CB  . ASP C 1 212 ? 3.812   -12.056 13.194  1.00 30.36  ? 212 ASP C CB  1 
ATOM   6158  C  CG  . ASP C 1 212 ? 4.225   -11.529 11.830  1.00 29.40  ? 212 ASP C CG  1 
ATOM   6159  O  OD1 . ASP C 1 212 ? 3.321   -11.434 10.915  1.00 26.32  ? 212 ASP C OD1 1 
ATOM   6160  O  OD2 . ASP C 1 212 ? 5.442   -11.203 11.767  1.00 37.72  ? 212 ASP C OD2 1 
ATOM   6161  N  N   . VAL C 1 213 ? 2.334   -15.415 13.000  1.00 27.93  ? 213 VAL C N   1 
ATOM   6162  C  CA  . VAL C 1 213 ? 2.446   -16.698 12.345  1.00 29.90  ? 213 VAL C CA  1 
ATOM   6163  C  C   . VAL C 1 213 ? 1.511   -16.783 11.138  1.00 30.39  ? 213 VAL C C   1 
ATOM   6164  O  O   . VAL C 1 213 ? 0.337   -16.496 11.215  1.00 31.36  ? 213 VAL C O   1 
ATOM   6165  C  CB  . VAL C 1 213 ? 2.213   -17.802 13.387  1.00 31.19  ? 213 VAL C CB  1 
ATOM   6166  C  CG1 . VAL C 1 213 ? 2.244   -19.154 12.710  1.00 34.07  ? 213 VAL C CG1 1 
ATOM   6167  C  CG2 . VAL C 1 213 ? 3.303   -17.782 14.467  1.00 33.73  ? 213 VAL C CG2 1 
ATOM   6168  N  N   . GLU C 1 214 ? 2.015   -17.229 9.996   1.00 28.46  ? 214 GLU C N   1 
ATOM   6169  C  CA  . GLU C 1 214 ? 1.196   -17.313 8.808   1.00 33.33  ? 214 GLU C CA  1 
ATOM   6170  C  C   . GLU C 1 214 ? 0.075   -18.326 9.001   1.00 37.28  ? 214 GLU C C   1 
ATOM   6171  O  O   . GLU C 1 214 ? 0.319   -19.359 9.614   1.00 35.13  ? 214 GLU C O   1 
ATOM   6172  C  CB  . GLU C 1 214 ? 2.135   -17.815 7.724   1.00 36.79  ? 214 GLU C CB  1 
ATOM   6173  C  CG  . GLU C 1 214 ? 1.530   -17.728 6.335   1.00 36.87  ? 214 GLU C CG  1 
ATOM   6174  C  CD  . GLU C 1 214 ? 2.595   -17.856 5.246   1.00 45.34  ? 214 GLU C CD  1 
ATOM   6175  O  OE1 . GLU C 1 214 ? 3.883   -17.759 5.436   1.00 42.63  ? 214 GLU C OE1 1 
ATOM   6176  O  OE2 . GLU C 1 214 ? 2.021   -18.015 4.148   1.00 39.20  ? 214 GLU C OE2 1 
ATOM   6177  N  N   . LEU C 1 215 ? -1.125  -18.026 8.485   1.00 34.86  ? 215 LEU C N   1 
ATOM   6178  C  CA  . LEU C 1 215 ? -2.246  -18.950 8.525   1.00 34.59  ? 215 LEU C CA  1 
ATOM   6179  C  C   . LEU C 1 215 ? -1.898  -20.125 7.652   1.00 35.91  ? 215 LEU C C   1 
ATOM   6180  O  O   . LEU C 1 215 ? -1.256  -19.946 6.631   1.00 36.59  ? 215 LEU C O   1 
ATOM   6181  C  CB  . LEU C 1 215 ? -3.487  -18.293 7.964   1.00 30.43  ? 215 LEU C CB  1 
ATOM   6182  C  CG  . LEU C 1 215 ? -4.113  -17.226 8.859   1.00 33.63  ? 215 LEU C CG  1 
ATOM   6183  C  CD1 . LEU C 1 215 ? -5.410  -16.747 8.277   1.00 40.87  ? 215 LEU C CD1 1 
ATOM   6184  C  CD2 . LEU C 1 215 ? -4.360  -17.759 10.232  1.00 36.38  ? 215 LEU C CD2 1 
ATOM   6185  N  N   . SER C 1 216 ? -2.333  -21.321 8.037   1.00 44.57  ? 216 SER C N   1 
ATOM   6186  C  CA  . SER C 1 216 ? -1.987  -22.487 7.233   1.00 51.96  ? 216 SER C CA  1 
ATOM   6187  C  C   . SER C 1 216 ? -2.757  -22.468 5.898   1.00 58.29  ? 216 SER C C   1 
ATOM   6188  O  O   . SER C 1 216 ? -3.825  -21.839 5.792   1.00 47.34  ? 216 SER C O   1 
ATOM   6189  C  CB  . SER C 1 216 ? -2.252  -23.738 8.014   1.00 49.97  ? 216 SER C CB  1 
ATOM   6190  O  OG  . SER C 1 216 ? -3.660  -23.885 8.181   1.00 52.41  ? 216 SER C OG  1 
ATOM   6191  N  N   . ASP C 1 217 ? -2.244  -23.216 4.899   1.00 56.94  ? 217 ASP C N   1 
ATOM   6192  C  CA  . ASP C 1 217 ? -2.900  -23.396 3.601   1.00 57.31  ? 217 ASP C CA  1 
ATOM   6193  C  C   . ASP C 1 217 ? -4.343  -23.888 3.747   1.00 56.36  ? 217 ASP C C   1 
ATOM   6194  O  O   . ASP C 1 217 ? -5.232  -23.378 3.062   1.00 44.20  ? 217 ASP C O   1 
ATOM   6195  C  CB  . ASP C 1 217 ? -2.029  -24.233 2.685   1.00 59.72  ? 217 ASP C CB  1 
ATOM   6196  C  CG  . ASP C 1 217 ? -0.638  -23.650 2.479   1.00 68.62  ? 217 ASP C CG  1 
ATOM   6197  O  OD1 . ASP C 1 217 ? -0.540  -22.424 2.232   1.00 67.08  ? 217 ASP C OD1 1 
ATOM   6198  O  OD2 . ASP C 1 217 ? 0.340   -24.410 2.627   1.00 87.36  ? 217 ASP C OD2 1 
ATOM   6199  N  N   . ASP C 1 218 ? -4.560  -24.824 4.707   1.00 87.34  ? 218 ASP C N   1 
ATOM   6200  C  CA  . ASP C 1 218 ? -5.841  -25.323 5.218   1.00 75.97  ? 218 ASP C CA  1 
ATOM   6201  C  C   . ASP C 1 218 ? -6.842  -24.147 5.316   1.00 74.14  ? 218 ASP C C   1 
ATOM   6202  O  O   . ASP C 1 218 ? -8.014  -24.368 5.046   1.00 79.34  ? 218 ASP C O   1 
ATOM   6203  C  CB  . ASP C 1 218 ? -5.657  -26.230 6.462   1.00 45.38  ? 218 ASP C CB  1 
ATOM   6204  N  N   . VAL C 1 219 ? -6.424  -22.903 5.667   1.00 60.92  ? 219 VAL C N   1 
ATOM   6205  C  CA  . VAL C 1 219 ? -7.372  -21.920 6.217   1.00 59.50  ? 219 VAL C CA  1 
ATOM   6206  C  C   . VAL C 1 219 ? -7.194  -20.504 5.653   1.00 51.42  ? 219 VAL C C   1 
ATOM   6207  O  O   . VAL C 1 219 ? -8.027  -19.614 5.849   1.00 41.14  ? 219 VAL C O   1 
ATOM   6208  C  CB  . VAL C 1 219 ? -7.389  -21.877 7.769   1.00 63.36  ? 219 VAL C CB  1 
ATOM   6209  C  CG1 . VAL C 1 219 ? -7.288  -23.286 8.348   1.00 67.62  ? 219 VAL C CG1 1 
ATOM   6210  C  CG2 . VAL C 1 219 ? -6.333  -20.954 8.369   1.00 58.65  ? 219 VAL C CG2 1 
ATOM   6211  N  N   . LYS C 1 220 ? -6.127  -20.262 4.901   1.00 54.07  ? 220 LYS C N   1 
ATOM   6212  C  CA  . LYS C 1 220 ? -5.872  -18.911 4.431   1.00 47.96  ? 220 LYS C CA  1 
ATOM   6213  C  C   . LYS C 1 220 ? -6.788  -18.596 3.262   1.00 36.58  ? 220 LYS C C   1 
ATOM   6214  O  O   . LYS C 1 220 ? -6.715  -19.212 2.228   1.00 37.81  ? 220 LYS C O   1 
ATOM   6215  C  CB  . LYS C 1 220 ? -4.423  -18.810 3.979   1.00 48.10  ? 220 LYS C CB  1 
ATOM   6216  C  CG  . LYS C 1 220 ? -3.960  -17.443 3.541   1.00 52.40  ? 220 LYS C CG  1 
ATOM   6217  C  CD  . LYS C 1 220 ? -2.548  -17.449 2.967   1.00 56.05  ? 220 LYS C CD  1 
ATOM   6218  C  CE  . LYS C 1 220 ? -1.649  -18.244 3.831   1.00 54.69  ? 220 LYS C CE  1 
ATOM   6219  N  NZ  . LYS C 1 220 ? -0.382  -18.373 3.150   1.00 52.75  ? 220 LYS C NZ  1 
ATOM   6220  N  N   . PRO C 1 221 ? -7.645  -17.579 3.360   1.00 32.23  ? 221 PRO C N   1 
ATOM   6221  C  CA  . PRO C 1 221 ? -8.512  -17.225 2.244   1.00 31.85  ? 221 PRO C CA  1 
ATOM   6222  C  C   . PRO C 1 221 ? -7.711  -16.841 1.016   1.00 33.76  ? 221 PRO C C   1 
ATOM   6223  O  O   . PRO C 1 221 ? -6.606  -16.297 1.107   1.00 39.14  ? 221 PRO C O   1 
ATOM   6224  C  CB  . PRO C 1 221 ? -9.304  -15.998 2.744   1.00 33.35  ? 221 PRO C CB  1 
ATOM   6225  C  CG  . PRO C 1 221 ? -9.162  -16.058 4.250   1.00 32.25  ? 221 PRO C CG  1 
ATOM   6226  C  CD  . PRO C 1 221 ? -7.836  -16.722 4.544   1.00 33.61  ? 221 PRO C CD  1 
ATOM   6227  N  N   . ALA C 1 222 ? -8.352  -17.023 -0.128  1.00 34.71  ? 222 ALA C N   1 
ATOM   6228  C  CA  . ALA C 1 222 ? -7.741  -16.702 -1.407  1.00 36.01  ? 222 ALA C CA  1 
ATOM   6229  C  C   . ALA C 1 222 ? -7.757  -15.195 -1.647  1.00 33.45  ? 222 ALA C C   1 
ATOM   6230  O  O   . ALA C 1 222 ? -6.958  -14.710 -2.478  1.00 44.59  ? 222 ALA C O   1 
ATOM   6231  C  CB  . ALA C 1 222 ? -8.423  -17.446 -2.555  1.00 44.62  ? 222 ALA C CB  1 
ATOM   6232  N  N   . ASP C 1 223 ? -8.626  -14.429 -0.958  1.00 27.95  ? 223 ASP C N   1 
ATOM   6233  C  CA  . ASP C 1 223 ? -8.576  -12.978 -1.163  1.00 28.27  ? 223 ASP C CA  1 
ATOM   6234  C  C   . ASP C 1 223 ? -7.880  -12.264 -0.001  1.00 27.04  ? 223 ASP C C   1 
ATOM   6235  O  O   . ASP C 1 223 ? -8.059  -11.028 0.156   1.00 25.38  ? 223 ASP C O   1 
ATOM   6236  C  CB  . ASP C 1 223 ? -9.936  -12.368 -1.482  1.00 31.83  ? 223 ASP C CB  1 
ATOM   6237  C  CG  . ASP C 1 223 ? -10.955 -12.669 -0.404  1.00 29.45  ? 223 ASP C CG  1 
ATOM   6238  O  OD1 . ASP C 1 223 ? -10.628 -13.506 0.480   1.00 25.77  ? 223 ASP C OD1 1 
ATOM   6239  O  OD2 . ASP C 1 223 ? -11.998 -12.023 -0.444  1.00 35.15  ? 223 ASP C OD2 1 
ATOM   6240  N  N   . SER C 1 224 ? -7.093  -13.041 0.767   1.00 22.91  ? 224 SER C N   1 
ATOM   6241  C  CA  . SER C 1 224 ? -6.222  -12.464 1.771   1.00 26.36  ? 224 SER C CA  1 
ATOM   6242  C  C   . SER C 1 224 ? -5.019  -11.804 1.108   1.00 26.53  ? 224 SER C C   1 
ATOM   6243  O  O   . SER C 1 224 ? -4.588  -12.234 0.033   1.00 24.78  ? 224 SER C O   1 
ATOM   6244  C  CB  . SER C 1 224 ? -5.777  -13.471 2.818   1.00 27.01  ? 224 SER C CB  1 
ATOM   6245  O  OG  . SER C 1 224 ? -4.835  -14.381 2.286   1.00 23.40  ? 224 SER C OG  1 
ATOM   6246  N  N   . HIS C 1 225 ? -4.470  -10.793 1.794   1.00 23.45  ? 225 HIS C N   1 
ATOM   6247  C  CA  . HIS C 1 225 ? -3.376  -10.012 1.258   1.00 25.60  ? 225 HIS C CA  1 
ATOM   6248  C  C   . HIS C 1 225 ? -2.154  -10.899 0.955   1.00 27.47  ? 225 HIS C C   1 
ATOM   6249  O  O   . HIS C 1 225 ? -1.499  -10.804 -0.083  1.00 28.63  ? 225 HIS C O   1 
ATOM   6250  C  CB  . HIS C 1 225 ? -3.084  -8.876  2.218   1.00 27.74  ? 225 HIS C CB  1 
ATOM   6251  C  CG  . HIS C 1 225 ? -1.939  -8.028  1.793   1.00 30.07  ? 225 HIS C CG  1 
ATOM   6252  N  ND1 . HIS C 1 225 ? -2.034  -7.296  0.650   1.00 31.02  ? 225 HIS C ND1 1 
ATOM   6253  C  CD2 . HIS C 1 225 ? -0.712  -7.747  2.325   1.00 31.37  ? 225 HIS C CD2 1 
ATOM   6254  C  CE1 . HIS C 1 225 ? -0.918  -6.592  0.504   1.00 35.78  ? 225 HIS C CE1 1 
ATOM   6255  N  NE2 . HIS C 1 225 ? -0.102  -6.846  1.511   1.00 31.59  ? 225 HIS C NE2 1 
ATOM   6256  N  N   . VAL C 1 226 ? -1.823  -11.781 1.868   1.00 24.92  ? 226 VAL C N   1 
ATOM   6257  C  CA  . VAL C 1 226 ? -0.689  -12.660 1.689   1.00 29.35  ? 226 VAL C CA  1 
ATOM   6258  C  C   . VAL C 1 226 ? -0.897  -13.645 0.556   1.00 28.07  ? 226 VAL C C   1 
ATOM   6259  O  O   . VAL C 1 226 ? 0.086   -13.976 -0.124  1.00 33.37  ? 226 VAL C O   1 
ATOM   6260  C  CB  . VAL C 1 226 ? -0.290  -13.361 2.994   1.00 31.01  ? 226 VAL C CB  1 
ATOM   6261  C  CG1 . VAL C 1 226 ? 0.573   -14.593 2.730   1.00 31.56  ? 226 VAL C CG1 1 
ATOM   6262  C  CG2 . VAL C 1 226 ? 0.419   -12.346 3.887   1.00 31.18  ? 226 VAL C CG2 1 
ATOM   6263  N  N   . ALA C 1 227 ? -2.138  -14.090 0.368   1.00 28.94  ? 227 ALA C N   1 
ATOM   6264  C  CA  . ALA C 1 227 ? -2.439  -14.996 -0.743  1.00 31.18  ? 227 ALA C CA  1 
ATOM   6265  C  C   . ALA C 1 227 ? -2.225  -14.288 -2.078  1.00 31.38  ? 227 ALA C C   1 
ATOM   6266  O  O   . ALA C 1 227 ? -1.529  -14.793 -2.932  1.00 26.70  ? 227 ALA C O   1 
ATOM   6267  C  CB  . ALA C 1 227 ? -3.837  -15.554 -0.661  1.00 29.55  ? 227 ALA C CB  1 
ATOM   6268  N  N   . LEU C 1 228 ? -2.789  -13.099 -2.222  1.00 30.82  ? 228 LEU C N   1 
ATOM   6269  C  CA  . LEU C 1 228 ? -2.686  -12.334 -3.456  1.00 34.51  ? 228 LEU C CA  1 
ATOM   6270  C  C   . LEU C 1 228 ? -1.266  -11.804 -3.747  1.00 35.24  ? 228 LEU C C   1 
ATOM   6271  O  O   . LEU C 1 228 ? -0.945  -11.613 -4.920  1.00 31.49  ? 228 LEU C O   1 
ATOM   6272  C  CB  . LEU C 1 228 ? -3.707  -11.190 -3.433  1.00 35.04  ? 228 LEU C CB  1 
ATOM   6273  C  CG  . LEU C 1 228 ? -5.152  -11.656 -3.575  1.00 39.02  ? 228 LEU C CG  1 
ATOM   6274  C  CD1 . LEU C 1 228 ? -6.096  -10.520 -3.328  1.00 38.27  ? 228 LEU C CD1 1 
ATOM   6275  C  CD2 . LEU C 1 228 ? -5.336  -12.232 -4.983  1.00 40.53  ? 228 LEU C CD2 1 
ATOM   6276  N  N   . THR C 1 229 ? -0.431  -11.500 -2.727  1.00 28.02  ? 229 THR C N   1 
ATOM   6277  C  CA  . THR C 1 229 ? 0.844   -10.926 -3.039  1.00 28.11  ? 229 THR C CA  1 
ATOM   6278  C  C   . THR C 1 229 ? 1.918   -12.013 -3.095  1.00 31.62  ? 229 THR C C   1 
ATOM   6279  O  O   . THR C 1 229 ? 3.080   -11.656 -3.293  1.00 36.28  ? 229 THR C O   1 
ATOM   6280  C  CB  . THR C 1 229 ? 1.158   -9.818  -2.049  1.00 25.42  ? 229 THR C CB  1 
ATOM   6281  O  OG1 . THR C 1 229 ? 1.060   -10.401 -0.760  1.00 22.83  ? 229 THR C OG1 1 
ATOM   6282  C  CG2 . THR C 1 229 ? 0.197   -8.664  -2.189  1.00 25.36  ? 229 THR C CG2 1 
ATOM   6283  N  N   . SER C 1 230 ? 1.554   -13.302 -2.969  1.00 36.51  ? 230 SER C N   1 
ATOM   6284  C  CA  . SER C 1 230 ? 2.462   -14.424 -3.254  1.00 37.81  ? 230 SER C CA  1 
ATOM   6285  C  C   . SER C 1 230 ? 2.349   -14.844 -4.705  1.00 37.26  ? 230 SER C C   1 
ATOM   6286  O  O   . SER C 1 230 ? 1.268   -15.188 -5.109  1.00 47.14  ? 230 SER C O   1 
ATOM   6287  C  CB  . SER C 1 230 ? 2.233   -15.613 -2.380  1.00 36.29  ? 230 SER C CB  1 
ATOM   6288  O  OG  . SER C 1 230 ? 2.352   -15.195 -1.016  1.00 44.50  ? 230 SER C OG  1 
ATOM   6289  N  N   . VAL C 1 231 ? 3.413   -14.681 -5.492  1.00 39.84  ? 231 VAL C N   1 
ATOM   6290  C  CA  . VAL C 1 231 ? 3.393   -15.016 -6.906  1.00 44.85  ? 231 VAL C CA  1 
ATOM   6291  C  C   . VAL C 1 231 ? 4.599   -15.913 -7.145  1.00 51.12  ? 231 VAL C C   1 
ATOM   6292  O  O   . VAL C 1 231 ? 5.708   -15.605 -6.699  1.00 47.54  ? 231 VAL C O   1 
ATOM   6293  C  CB  . VAL C 1 231 ? 3.337   -13.827 -7.893  1.00 52.27  ? 231 VAL C CB  1 
ATOM   6294  C  CG1 . VAL C 1 231 ? 2.476   -12.685 -7.377  1.00 55.08  ? 231 VAL C CG1 1 
ATOM   6295  C  CG2 . VAL C 1 231 ? 4.688   -13.254 -8.289  1.00 64.70  ? 231 VAL C CG2 1 
ATOM   6296  N  N   . THR C 1 232 ? 4.376   -17.059 -7.805  1.00 61.78  ? 232 THR C N   1 
ATOM   6297  C  CA  . THR C 1 232 ? 5.518   -17.823 -8.294  1.00 69.95  ? 232 THR C CA  1 
ATOM   6298  C  C   . THR C 1 232 ? 5.657   -17.507 -9.786  1.00 56.53  ? 232 THR C C   1 
ATOM   6299  O  O   . THR C 1 232 ? 4.680   -17.160 -10.429 1.00 55.90  ? 232 THR C O   1 
ATOM   6300  C  CB  . THR C 1 232 ? 5.371   -19.301 -7.935  1.00 70.82  ? 232 THR C CB  1 
ATOM   6301  O  OG1 . THR C 1 232 ? 4.277   -19.547 -8.794  1.00 60.64  ? 232 THR C OG1 1 
ATOM   6302  C  CG2 . THR C 1 232 ? 5.078   -19.558 -6.459  1.00 63.06  ? 232 THR C CG2 1 
ATOM   6303  N  N   . GLY C 1 233 ? 6.890   -17.430 -10.279 1.00 61.12  ? 233 GLY C N   1 
ATOM   6304  C  CA  . GLY C 1 233 ? 7.125   -17.047 -11.659 1.00 77.37  ? 233 GLY C CA  1 
ATOM   6305  C  C   . GLY C 1 233 ? 6.974   -18.266 -12.563 1.00 101.23 ? 233 GLY C C   1 
ATOM   6306  O  O   . GLY C 1 233 ? 6.821   -19.379 -12.053 1.00 90.72  ? 233 GLY C O   1 
ATOM   6307  N  N   . PRO C 1 234 ? 6.941   -18.082 -13.904 1.00 124.71 ? 234 PRO C N   1 
ATOM   6308  C  CA  . PRO C 1 234 ? 7.018   -19.244 -14.801 1.00 111.84 ? 234 PRO C CA  1 
ATOM   6309  C  C   . PRO C 1 234 ? 7.879   -20.454 -14.348 1.00 89.41  ? 234 PRO C C   1 
ATOM   6310  O  O   . PRO C 1 234 ? 7.364   -21.572 -14.319 1.00 63.12  ? 234 PRO C O   1 
ATOM   6311  C  CB  . PRO C 1 234 ? 7.482   -18.530 -16.116 1.00 106.57 ? 234 PRO C CB  1 
ATOM   6312  C  CG  . PRO C 1 234 ? 6.796   -17.132 -16.081 1.00 88.76  ? 234 PRO C CG  1 
ATOM   6313  C  CD  . PRO C 1 234 ? 6.749   -16.776 -14.598 1.00 92.11  ? 234 PRO C CD  1 
ATOM   6314  N  N   . ASP C 1 235 ? 9.137   -20.258 -13.880 1.00 85.78  ? 235 ASP C N   1 
ATOM   6315  C  CA  . ASP C 1 235 ? 10.011  -21.339 -13.393 1.00 78.10  ? 235 ASP C CA  1 
ATOM   6316  C  C   . ASP C 1 235 ? 9.665   -21.934 -12.011 1.00 81.72  ? 235 ASP C C   1 
ATOM   6317  O  O   . ASP C 1 235 ? 10.421  -22.770 -11.542 1.00 61.44  ? 235 ASP C O   1 
ATOM   6318  C  CB  . ASP C 1 235 ? 11.463  -20.896 -13.228 1.00 77.67  ? 235 ASP C CB  1 
ATOM   6319  C  CG  . ASP C 1 235 ? 11.739  -19.674 -12.342 1.00 84.98  ? 235 ASP C CG  1 
ATOM   6320  O  OD1 . ASP C 1 235 ? 11.663  -19.760 -11.064 1.00 72.70  ? 235 ASP C OD1 1 
ATOM   6321  O  OD2 . ASP C 1 235 ? 12.101  -18.629 -12.938 1.00 77.71  ? 235 ASP C OD2 1 
ATOM   6322  N  N   . GLY C 1 236 ? 8.626   -21.501 -11.277 1.00 85.19  ? 236 GLY C N   1 
ATOM   6323  C  CA  . GLY C 1 236 ? 8.291   -22.153 -10.017 1.00 73.44  ? 236 GLY C CA  1 
ATOM   6324  C  C   . GLY C 1 236 ? 8.890   -21.474 -8.781  1.00 86.12  ? 236 GLY C C   1 
ATOM   6325  O  O   . GLY C 1 236 ? 8.323   -21.675 -7.716  1.00 72.76  ? 236 GLY C O   1 
ATOM   6326  N  N   . SER C 1 237 ? 10.033  -20.739 -8.882  1.00 91.03  ? 237 SER C N   1 
ATOM   6327  C  CA  . SER C 1 237 ? 10.579  -19.985 -7.740  1.00 72.48  ? 237 SER C CA  1 
ATOM   6328  C  C   . SER C 1 237 ? 9.656   -18.790 -7.465  1.00 72.55  ? 237 SER C C   1 
ATOM   6329  O  O   . SER C 1 237 ? 8.983   -18.288 -8.381  1.00 59.06  ? 237 SER C O   1 
ATOM   6330  C  CB  . SER C 1 237 ? 12.073  -19.574 -7.866  1.00 47.43  ? 237 SER C CB  1 
ATOM   6331  N  N   . ASP C 1 238 ? 9.575   -18.366 -6.189  1.00 70.90  ? 238 ASP C N   1 
ATOM   6332  C  CA  . ASP C 1 238 ? 8.786   -17.188 -5.837  1.00 68.60  ? 238 ASP C CA  1 
ATOM   6333  C  C   . ASP C 1 238 ? 9.435   -15.908 -6.359  1.00 52.16  ? 238 ASP C C   1 
ATOM   6334  O  O   . ASP C 1 238 ? 10.655  -15.772 -6.395  1.00 47.61  ? 238 ASP C O   1 
ATOM   6335  C  CB  . ASP C 1 238 ? 8.685   -16.864 -4.356  1.00 74.06  ? 238 ASP C CB  1 
ATOM   6336  C  CG  . ASP C 1 238 ? 8.223   -17.984 -3.464  1.00 63.66  ? 238 ASP C CG  1 
ATOM   6337  O  OD1 . ASP C 1 238 ? 7.179   -18.589 -3.823  1.00 57.89  ? 238 ASP C OD1 1 
ATOM   6338  O  OD2 . ASP C 1 238 ? 8.928   -18.175 -2.450  1.00 51.31  ? 238 ASP C OD2 1 
ATOM   6339  N  N   . LEU C 1 239 ? 8.575   -14.959 -6.695  1.00 44.46  ? 239 LEU C N   1 
ATOM   6340  C  CA  . LEU C 1 239 ? 9.006   -13.620 -7.066  1.00 42.82  ? 239 LEU C CA  1 
ATOM   6341  C  C   . LEU C 1 239 ? 8.893   -12.708 -5.856  1.00 38.26  ? 239 LEU C C   1 
ATOM   6342  O  O   . LEU C 1 239 ? 7.804   -12.500 -5.332  1.00 36.44  ? 239 LEU C O   1 
ATOM   6343  C  CB  . LEU C 1 239 ? 8.108   -13.108 -8.171  1.00 46.70  ? 239 LEU C CB  1 
ATOM   6344  C  CG  . LEU C 1 239 ? 8.147   -13.889 -9.479  1.00 56.34  ? 239 LEU C CG  1 
ATOM   6345  C  CD1 . LEU C 1 239 ? 7.193   -13.178 -10.396 1.00 65.52  ? 239 LEU C CD1 1 
ATOM   6346  C  CD2 . LEU C 1 239 ? 9.562   -13.985 -10.058 1.00 59.14  ? 239 LEU C CD2 1 
ATOM   6347  N  N   . GLU C 1 240 ? 10.016  -12.127 -5.428  1.00 37.82  ? 240 GLU C N   1 
ATOM   6348  C  CA  . GLU C 1 240 ? 10.030  -11.328 -4.214  1.00 34.79  ? 240 GLU C CA  1 
ATOM   6349  C  C   . GLU C 1 240 ? 10.307  -9.852  -4.502  1.00 29.18  ? 240 GLU C C   1 
ATOM   6350  O  O   . GLU C 1 240 ? 10.947  -9.539  -5.496  1.00 33.35  ? 240 GLU C O   1 
ATOM   6351  C  CB  . GLU C 1 240 ? 11.074  -11.948 -3.316  1.00 38.29  ? 240 GLU C CB  1 
ATOM   6352  C  CG  . GLU C 1 240 ? 10.971  -13.464 -3.157  1.00 42.51  ? 240 GLU C CG  1 
ATOM   6353  C  CD  . GLU C 1 240 ? 12.010  -13.898 -2.120  1.00 43.34  ? 240 GLU C CD  1 
ATOM   6354  O  OE1 . GLU C 1 240 ? 13.219  -13.976 -2.442  1.00 47.68  ? 240 GLU C OE1 1 
ATOM   6355  O  OE2 . GLU C 1 240 ? 11.638  -14.034 -0.948  1.00 43.19  ? 240 GLU C OE2 1 
ATOM   6356  N  N   . ILE C 1 241 ? 9.786   -8.962  -3.645  1.00 25.10  ? 241 ILE C N   1 
ATOM   6357  C  CA  . ILE C 1 241 ? 10.175  -7.557  -3.616  1.00 26.80  ? 241 ILE C CA  1 
ATOM   6358  C  C   . ILE C 1 241 ? 10.728  -7.199  -2.240  1.00 27.39  ? 241 ILE C C   1 
ATOM   6359  O  O   . ILE C 1 241 ? 10.601  -7.997  -1.321  1.00 27.75  ? 241 ILE C O   1 
ATOM   6360  C  CB  . ILE C 1 241 ? 9.035   -6.614  -4.040  1.00 27.13  ? 241 ILE C CB  1 
ATOM   6361  C  CG1 . ILE C 1 241 ? 7.911   -6.562  -3.031  1.00 31.96  ? 241 ILE C CG1 1 
ATOM   6362  C  CG2 . ILE C 1 241 ? 8.528   -6.978  -5.425  1.00 27.98  ? 241 ILE C CG2 1 
ATOM   6363  C  CD1 . ILE C 1 241 ? 6.813   -5.562  -3.409  1.00 30.69  ? 241 ILE C CD1 1 
ATOM   6364  N  N   . LEU C 1 242 ? 11.316  -5.998  -2.132  1.00 23.33  ? 242 LEU C N   1 
ATOM   6365  C  CA  . LEU C 1 242 ? 11.741  -5.468  -0.864  1.00 22.73  ? 242 LEU C CA  1 
ATOM   6366  C  C   . LEU C 1 242 ? 10.900  -4.263  -0.522  1.00 21.91  ? 242 LEU C C   1 
ATOM   6367  O  O   . LEU C 1 242 ? 10.963  -3.279  -1.235  1.00 21.30  ? 242 LEU C O   1 
ATOM   6368  C  CB  . LEU C 1 242 ? 13.186  -5.015  -0.980  1.00 26.21  ? 242 LEU C CB  1 
ATOM   6369  C  CG  . LEU C 1 242 ? 13.841  -4.617  0.335   1.00 26.80  ? 242 LEU C CG  1 
ATOM   6370  C  CD1 . LEU C 1 242 ? 13.939  -5.700  1.342   1.00 28.45  ? 242 LEU C CD1 1 
ATOM   6371  C  CD2 . LEU C 1 242 ? 15.237  -4.159  0.035   1.00 28.88  ? 242 LEU C CD2 1 
ATOM   6372  N  N   . ARG C 1 243 ? 10.195  -4.344  0.590   1.00 21.64  ? 243 ARG C N   1 
ATOM   6373  C  CA  . ARG C 1 243 ? 9.289   -3.282  1.002   1.00 21.31  ? 243 ARG C CA  1 
ATOM   6374  C  C   . ARG C 1 243 ? 9.816   -2.602  2.253   1.00 21.23  ? 243 ARG C C   1 
ATOM   6375  O  O   . ARG C 1 243 ? 10.510  -3.247  3.035   1.00 22.56  ? 243 ARG C O   1 
ATOM   6376  C  CB  . ARG C 1 243 ? 7.954   -3.851  1.451   1.00 22.41  ? 243 ARG C CB  1 
ATOM   6377  C  CG  . ARG C 1 243 ? 7.207   -4.442  0.282   1.00 25.96  ? 243 ARG C CG  1 
ATOM   6378  C  CD  . ARG C 1 243 ? 6.021   -5.222  0.838   1.00 29.25  ? 243 ARG C CD  1 
ATOM   6379  N  NE  . ARG C 1 243 ? 6.556   -6.466  1.406   1.00 31.40  ? 243 ARG C NE  1 
ATOM   6380  C  CZ  . ARG C 1 243 ? 6.328   -6.943  2.635   1.00 31.58  ? 243 ARG C CZ  1 
ATOM   6381  N  NH1 . ARG C 1 243 ? 5.475   -6.323  3.437   1.00 27.84  ? 243 ARG C NH1 1 
ATOM   6382  N  NH2 . ARG C 1 243 ? 6.887   -8.102  2.978   1.00 36.80  ? 243 ARG C NH2 1 
ATOM   6383  N  N   . ASP C 1 244 ? 9.542   -1.287  2.406   1.00 20.79  ? 244 ASP C N   1 
ATOM   6384  C  CA  . ASP C 1 244 ? 9.827   -0.625  3.669   1.00 24.42  ? 244 ASP C CA  1 
ATOM   6385  C  C   . ASP C 1 244 ? 8.690   0.333   4.006   1.00 23.92  ? 244 ASP C C   1 
ATOM   6386  O  O   . ASP C 1 244 ? 8.874   1.514   4.148   1.00 28.33  ? 244 ASP C O   1 
ATOM   6387  C  CB  . ASP C 1 244 ? 11.234  -0.051  3.664   1.00 27.73  ? 244 ASP C CB  1 
ATOM   6388  C  CG  . ASP C 1 244 ? 11.846  0.263   5.016   1.00 31.36  ? 244 ASP C CG  1 
ATOM   6389  O  OD1 . ASP C 1 244 ? 11.260  -0.192  6.061   1.00 32.47  ? 244 ASP C OD1 1 
ATOM   6390  O  OD2 . ASP C 1 244 ? 12.801  1.073   4.989   1.00 36.25  ? 244 ASP C OD2 1 
ATOM   6391  N  N   . ASN C 1 245 ? 7.510   -0.231  4.196   1.00 25.81  ? 245 ASN C N   1 
ATOM   6392  C  CA  . ASN C 1 245 ? 6.294   0.506   4.505   1.00 25.36  ? 245 ASN C CA  1 
ATOM   6393  C  C   . ASN C 1 245 ? 6.438   1.260   5.816   1.00 22.21  ? 245 ASN C C   1 
ATOM   6394  O  O   . ASN C 1 245 ? 6.937   0.731   6.775   1.00 24.99  ? 245 ASN C O   1 
ATOM   6395  C  CB  . ASN C 1 245 ? 5.114   -0.438  4.594   1.00 24.08  ? 245 ASN C CB  1 
ATOM   6396  C  CG  . ASN C 1 245 ? 4.898   -1.259  3.332   1.00 31.97  ? 245 ASN C CG  1 
ATOM   6397  O  OD1 . ASN C 1 245 ? 5.495   -0.991  2.267   1.00 28.28  ? 245 ASN C OD1 1 
ATOM   6398  N  ND2 . ASN C 1 245 ? 4.033   -2.268  3.434   1.00 40.72  ? 245 ASN C ND2 1 
ATOM   6399  N  N   . MET C 1 246 ? 5.962   2.486   5.850   1.00 20.57  ? 246 MET C N   1 
ATOM   6400  C  CA  . MET C 1 246 ? 6.025   3.317   7.024   1.00 21.25  ? 246 MET C CA  1 
ATOM   6401  C  C   . MET C 1 246 ? 4.621   3.846   7.339   1.00 22.16  ? 246 MET C C   1 
ATOM   6402  O  O   . MET C 1 246 ? 3.980   4.476   6.516   1.00 20.87  ? 246 MET C O   1 
ATOM   6403  C  CB  . MET C 1 246 ? 6.966   4.537   6.843   1.00 25.72  ? 246 MET C CB  1 
ATOM   6404  C  CG  . MET C 1 246 ? 8.450   4.166   6.737   1.00 28.56  ? 246 MET C CG  1 
ATOM   6405  S  SD  . MET C 1 246 ? 9.098   3.323   8.200   1.00 24.91  ? 246 MET C SD  1 
ATOM   6406  C  CE  . MET C 1 246 ? 9.411   4.857   9.104   1.00 27.49  ? 246 MET C CE  1 
ATOM   6407  N  N   . PRO C 1 247 ? 4.216   3.754   8.606   1.00 20.12  ? 247 PRO C N   1 
ATOM   6408  C  CA  . PRO C 1 247 ? 3.094   4.505   9.119   1.00 19.99  ? 247 PRO C CA  1 
ATOM   6409  C  C   . PRO C 1 247 ? 3.330   5.992   9.098   1.00 19.25  ? 247 PRO C C   1 
ATOM   6410  O  O   . PRO C 1 247 ? 4.437   6.467   9.274   1.00 17.94  ? 247 PRO C O   1 
ATOM   6411  C  CB  . PRO C 1 247 ? 3.002   4.049   10.558  1.00 25.19  ? 247 PRO C CB  1 
ATOM   6412  C  CG  . PRO C 1 247 ? 3.843   2.760   10.684  1.00 25.57  ? 247 PRO C CG  1 
ATOM   6413  C  CD  . PRO C 1 247 ? 4.878   2.918   9.616   1.00 24.12  ? 247 PRO C CD  1 
ATOM   6414  N  N   . PHE C 1 248 ? 2.240   6.728   8.960   1.00 19.16  ? 248 PHE C N   1 
ATOM   6415  C  CA  . PHE C 1 248 ? 2.273   8.162   9.090   1.00 19.57  ? 248 PHE C CA  1 
ATOM   6416  C  C   . PHE C 1 248 ? 0.870   8.557   9.494   1.00 21.18  ? 248 PHE C C   1 
ATOM   6417  O  O   . PHE C 1 248 ? -0.081  7.828   9.296   1.00 23.58  ? 248 PHE C O   1 
ATOM   6418  C  CB  . PHE C 1 248 ? 2.718   8.869   7.811   1.00 19.56  ? 248 PHE C CB  1 
ATOM   6419  C  CG  . PHE C 1 248 ? 1.711   8.759   6.708   1.00 19.69  ? 248 PHE C CG  1 
ATOM   6420  C  CD1 . PHE C 1 248 ? 1.711   7.641   5.866   1.00 22.02  ? 248 PHE C CD1 1 
ATOM   6421  C  CD2 . PHE C 1 248 ? 0.757   9.764   6.525   1.00 16.90  ? 248 PHE C CD2 1 
ATOM   6422  C  CE1 . PHE C 1 248 ? 0.748   7.544   4.834   1.00 23.46  ? 248 PHE C CE1 1 
ATOM   6423  C  CE2 . PHE C 1 248 ? -0.216  9.662   5.527   1.00 19.54  ? 248 PHE C CE2 1 
ATOM   6424  C  CZ  . PHE C 1 248 ? -0.235  8.548   4.667   1.00 22.25  ? 248 PHE C CZ  1 
ATOM   6425  N  N   . GLY C 1 249 ? 0.696   9.746   10.012  1.00 23.13  ? 249 GLY C N   1 
ATOM   6426  C  CA  . GLY C 1 249 ? -0.667  10.165  10.220  1.00 22.07  ? 249 GLY C CA  1 
ATOM   6427  C  C   . GLY C 1 249 ? -0.753  11.542  10.852  1.00 26.53  ? 249 GLY C C   1 
ATOM   6428  O  O   . GLY C 1 249 ? 0.238   12.151  11.219  1.00 28.73  ? 249 GLY C O   1 
ATOM   6429  N  N   . SER C 1 250 ? -1.987  11.948  11.075  1.00 26.83  ? 250 SER C N   1 
ATOM   6430  C  CA  . SER C 1 250 ? -2.316  13.136  11.838  1.00 27.61  ? 250 SER C CA  1 
ATOM   6431  C  C   . SER C 1 250 ? -3.617  12.884  12.614  1.00 27.34  ? 250 SER C C   1 
ATOM   6432  O  O   . SER C 1 250 ? -4.614  12.416  12.032  1.00 23.04  ? 250 SER C O   1 
ATOM   6433  C  CB  . SER C 1 250 ? -2.403  14.266  10.844  1.00 27.83  ? 250 SER C CB  1 
ATOM   6434  O  OG  . SER C 1 250 ? -3.434  15.127  11.252  1.00 28.37  ? 250 SER C OG  1 
ATOM   6435  N  N   . VAL C 1 251 ? -3.621  13.067  13.947  1.00 32.31  ? 251 VAL C N   1 
ATOM   6436  C  CA  . VAL C 1 251 ? -4.813  12.596  14.693  1.00 35.59  ? 251 VAL C CA  1 
ATOM   6437  C  C   . VAL C 1 251 ? -5.983  13.563  14.514  1.00 30.67  ? 251 VAL C C   1 
ATOM   6438  O  O   . VAL C 1 251 ? -7.124  13.159  14.401  1.00 35.76  ? 251 VAL C O   1 
ATOM   6439  C  CB  . VAL C 1 251 ? -4.692  12.267  16.185  1.00 34.63  ? 251 VAL C CB  1 
ATOM   6440  C  CG1 . VAL C 1 251 ? -3.770  11.094  16.410  1.00 41.10  ? 251 VAL C CG1 1 
ATOM   6441  C  CG2 . VAL C 1 251 ? -4.182  13.472  16.914  1.00 43.24  ? 251 VAL C CG2 1 
ATOM   6442  N  N   . GLY C 1 252 ? -5.678  14.845  14.451  1.00 29.18  ? 252 GLY C N   1 
ATOM   6443  C  CA  . GLY C 1 252 ? -6.703  15.849  14.319  1.00 31.29  ? 252 GLY C CA  1 
ATOM   6444  C  C   . GLY C 1 252 ? -7.402  15.760  12.974  1.00 32.20  ? 252 GLY C C   1 
ATOM   6445  O  O   . GLY C 1 252 ? -8.550  16.030  12.936  1.00 35.71  ? 252 GLY C O   1 
ATOM   6446  N  N   . ARG C 1 253 ? -6.753  15.422  11.875  1.00 37.61  ? 253 ARG C N   1 
ATOM   6447  C  CA  . ARG C 1 253 ? -7.433  15.241  10.592  1.00 34.53  ? 253 ARG C CA  1 
ATOM   6448  C  C   . ARG C 1 253 ? -8.027  13.820  10.463  1.00 31.32  ? 253 ARG C C   1 
ATOM   6449  O  O   . ARG C 1 253 ? -8.521  13.442  9.462   1.00 33.00  ? 253 ARG C O   1 
ATOM   6450  C  CB  . ARG C 1 253 ? -6.430  15.473  9.442   1.00 31.90  ? 253 ARG C CB  1 
ATOM   6451  C  CG  . ARG C 1 253 ? -5.976  16.920  9.398   1.00 36.92  ? 253 ARG C CG  1 
ATOM   6452  C  CD  . ARG C 1 253 ? -5.273  17.376  8.095   1.00 43.99  ? 253 ARG C CD  1 
ATOM   6453  N  NE  . ARG C 1 253 ? -3.876  16.923  8.018   1.00 55.74  ? 253 ARG C NE  1 
ATOM   6454  N  N   . GLU C 1 254 ? -7.922  12.953  11.426  1.00 31.37  ? 254 GLU C N   1 
ATOM   6455  C  CA  . GLU C 1 254 ? -8.133  11.534  11.187  1.00 34.75  ? 254 GLU C CA  1 
ATOM   6456  C  C   . GLU C 1 254 ? -7.460  10.940  9.953   1.00 30.18  ? 254 GLU C C   1 
ATOM   6457  O  O   . GLU C 1 254 ? -8.052  10.088  9.340   1.00 30.63  ? 254 GLU C O   1 
ATOM   6458  C  CB  . GLU C 1 254 ? -9.614  11.246  11.123  1.00 43.87  ? 254 GLU C CB  1 
ATOM   6459  C  CG  . GLU C 1 254 ? -10.317 11.380  12.471  1.00 59.42  ? 254 GLU C CG  1 
ATOM   6460  C  CD  . GLU C 1 254 ? -11.831 11.393  12.268  1.00 60.04  ? 254 GLU C CD  1 
ATOM   6461  O  OE1 . GLU C 1 254 ? -12.303 10.263  12.123  1.00 53.79  ? 254 GLU C OE1 1 
ATOM   6462  O  OE2 . GLU C 1 254 ? -12.489 12.463  12.123  1.00 64.64  ? 254 GLU C OE2 1 
ATOM   6463  N  N   . GLU C 1 255 ? -6.184  11.208  9.689   1.00 29.81  ? 255 GLU C N   1 
ATOM   6464  C  CA  . GLU C 1 255 ? -5.428  10.479  8.684   1.00 29.66  ? 255 GLU C CA  1 
ATOM   6465  C  C   . GLU C 1 255 ? -4.553  9.428   9.353   1.00 28.84  ? 255 GLU C C   1 
ATOM   6466  O  O   . GLU C 1 255 ? -3.722  9.743   10.185  1.00 29.04  ? 255 GLU C O   1 
ATOM   6467  C  CB  . GLU C 1 255 ? -4.468  11.364  7.909   1.00 43.38  ? 255 GLU C CB  1 
ATOM   6468  C  CG  . GLU C 1 255 ? -5.176  12.425  7.059   1.00 58.29  ? 255 GLU C CG  1 
ATOM   6469  C  CD  . GLU C 1 255 ? -4.157  13.409  6.495   1.00 65.78  ? 255 GLU C CD  1 
ATOM   6470  O  OE1 . GLU C 1 255 ? -2.921  13.006  6.372   1.00 48.53  ? 255 GLU C OE1 1 
ATOM   6471  O  OE2 . GLU C 1 255 ? -4.647  14.581  6.281   1.00 55.45  ? 255 GLU C OE2 1 
ATOM   6472  N  N   . PHE C 1 256 ? -4.776  8.171   9.031   1.00 24.99  ? 256 PHE C N   1 
ATOM   6473  C  CA  . PHE C 1 256 ? -3.936  7.091   9.486   1.00 27.99  ? 256 PHE C CA  1 
ATOM   6474  C  C   . PHE C 1 256 ? -3.476  6.355   8.230   1.00 26.44  ? 256 PHE C C   1 
ATOM   6475  O  O   . PHE C 1 256 ? -4.294  5.901   7.461   1.00 29.05  ? 256 PHE C O   1 
ATOM   6476  C  CB  . PHE C 1 256 ? -4.717  6.176   10.452  1.00 30.27  ? 256 PHE C CB  1 
ATOM   6477  C  CG  . PHE C 1 256 ? -5.320  6.941   11.610  1.00 32.61  ? 256 PHE C CG  1 
ATOM   6478  C  CD1 . PHE C 1 256 ? -4.572  7.241   12.747  1.00 38.85  ? 256 PHE C CD1 1 
ATOM   6479  C  CD2 . PHE C 1 256 ? -6.624  7.445   11.529  1.00 38.46  ? 256 PHE C CD2 1 
ATOM   6480  C  CE1 . PHE C 1 256 ? -5.116  8.024   13.754  1.00 35.58  ? 256 PHE C CE1 1 
ATOM   6481  C  CE2 . PHE C 1 256 ? -7.176  8.175   12.570  1.00 29.68  ? 256 PHE C CE2 1 
ATOM   6482  C  CZ  . PHE C 1 256 ? -6.399  8.513   13.640  1.00 32.48  ? 256 PHE C CZ  1 
ATOM   6483  N  N   . GLY C 1 257 ? -2.186  6.341   7.956   1.00 24.10  ? 257 GLY C N   1 
ATOM   6484  C  CA  . GLY C 1 257 ? -1.708  5.904   6.656   1.00 23.92  ? 257 GLY C CA  1 
ATOM   6485  C  C   . GLY C 1 257 ? -0.592  4.847   6.720   1.00 22.28  ? 257 GLY C C   1 
ATOM   6486  O  O   . GLY C 1 257 ? 0.028   4.595   7.773   1.00 21.43  ? 257 GLY C O   1 
ATOM   6487  N  N   . THR C 1 258 ? -0.420  4.203   5.558   1.00 19.73  ? 258 THR C N   1 
ATOM   6488  C  CA  . THR C 1 258 ? 0.705   3.374   5.262   1.00 20.78  ? 258 THR C CA  1 
ATOM   6489  C  C   . THR C 1 258 ? 1.321   3.948   3.992   1.00 23.49  ? 258 THR C C   1 
ATOM   6490  O  O   . THR C 1 258 ? 0.622   4.084   3.001   1.00 23.60  ? 258 THR C O   1 
ATOM   6491  C  CB  . THR C 1 258 ? 0.271   1.940   5.017   1.00 23.63  ? 258 THR C CB  1 
ATOM   6492  O  OG1 . THR C 1 258 ? -0.192  1.407   6.244   1.00 24.76  ? 258 THR C OG1 1 
ATOM   6493  C  CG2 . THR C 1 258 ? 1.450   1.083   4.600   1.00 27.29  ? 258 THR C CG2 1 
ATOM   6494  N  N   . TYR C 1 259 ? 2.601   4.320   4.057   1.00 21.26  ? 259 TYR C N   1 
ATOM   6495  C  CA  . TYR C 1 259 ? 3.354   4.721   2.892   1.00 20.35  ? 259 TYR C CA  1 
ATOM   6496  C  C   . TYR C 1 259 ? 4.024   3.451   2.365   1.00 21.27  ? 259 TYR C C   1 
ATOM   6497  O  O   . TYR C 1 259 ? 4.930   2.925   2.990   1.00 18.86  ? 259 TYR C O   1 
ATOM   6498  C  CB  . TYR C 1 259 ? 4.353   5.849   3.142   1.00 21.03  ? 259 TYR C CB  1 
ATOM   6499  C  CG  . TYR C 1 259 ? 4.732   6.598   1.875   1.00 21.59  ? 259 TYR C CG  1 
ATOM   6500  C  CD1 . TYR C 1 259 ? 5.683   6.102   1.016   1.00 21.71  ? 259 TYR C CD1 1 
ATOM   6501  C  CD2 . TYR C 1 259 ? 4.109   7.773   1.514   1.00 23.94  ? 259 TYR C CD2 1 
ATOM   6502  C  CE1 . TYR C 1 259 ? 6.014   6.770   -0.154  1.00 24.93  ? 259 TYR C CE1 1 
ATOM   6503  C  CE2 . TYR C 1 259 ? 4.402   8.427   0.333   1.00 24.25  ? 259 TYR C CE2 1 
ATOM   6504  C  CZ  . TYR C 1 259 ? 5.376   7.943   -0.510  1.00 28.87  ? 259 TYR C CZ  1 
ATOM   6505  O  OH  . TYR C 1 259 ? 5.724   8.643   -1.666  1.00 34.45  ? 259 TYR C OH  1 
ATOM   6506  N  N   . PHE C 1 260 ? 3.524   2.934   1.227   1.00 20.50  ? 260 PHE C N   1 
ATOM   6507  C  CA  . PHE C 1 260 ? 4.091   1.763   0.609   1.00 18.77  ? 260 PHE C CA  1 
ATOM   6508  C  C   . PHE C 1 260 ? 5.220   2.172   -0.302  1.00 18.53  ? 260 PHE C C   1 
ATOM   6509  O  O   . PHE C 1 260 ? 5.077   3.053   -1.141  1.00 23.92  ? 260 PHE C O   1 
ATOM   6510  C  CB  . PHE C 1 260 ? 3.035   1.075   -0.247  1.00 20.43  ? 260 PHE C CB  1 
ATOM   6511  C  CG  . PHE C 1 260 ? 3.615   -0.054  -1.069  1.00 19.88  ? 260 PHE C CG  1 
ATOM   6512  C  CD1 . PHE C 1 260 ? 3.824   -1.300  -0.495  1.00 20.66  ? 260 PHE C CD1 1 
ATOM   6513  C  CD2 . PHE C 1 260 ? 3.911   0.131   -2.402  1.00 22.45  ? 260 PHE C CD2 1 
ATOM   6514  C  CE1 . PHE C 1 260 ? 4.415   -2.305  -1.200  1.00 21.23  ? 260 PHE C CE1 1 
ATOM   6515  C  CE2 . PHE C 1 260 ? 4.485   -0.895  -3.122  1.00 22.43  ? 260 PHE C CE2 1 
ATOM   6516  C  CZ  . PHE C 1 260 ? 4.789   -2.091  -2.499  1.00 20.79  ? 260 PHE C CZ  1 
ATOM   6517  N  N   . ILE C 1 261 ? 6.351   1.529   -0.145  1.00 18.52  ? 261 ILE C N   1 
ATOM   6518  C  CA  . ILE C 1 261 ? 7.410   1.610   -1.124  1.00 18.67  ? 261 ILE C CA  1 
ATOM   6519  C  C   . ILE C 1 261 ? 7.938   0.184   -1.310  1.00 19.38  ? 261 ILE C C   1 
ATOM   6520  O  O   . ILE C 1 261 ? 8.194   -0.560  -0.387  1.00 24.12  ? 261 ILE C O   1 
ATOM   6521  C  CB  . ILE C 1 261 ? 8.490   2.634   -0.742  1.00 20.02  ? 261 ILE C CB  1 
ATOM   6522  C  CG1 . ILE C 1 261 ? 9.506   2.740   -1.846  1.00 24.09  ? 261 ILE C CG1 1 
ATOM   6523  C  CG2 . ILE C 1 261 ? 9.175   2.262   0.562   1.00 22.01  ? 261 ILE C CG2 1 
ATOM   6524  C  CD1 . ILE C 1 261 ? 10.481  3.889   -1.722  1.00 22.19  ? 261 ILE C CD1 1 
ATOM   6525  N  N   . GLY C 1 262 ? 8.029   -0.230  -2.543  1.00 20.05  ? 262 GLY C N   1 
ATOM   6526  C  CA  . GLY C 1 262 ? 8.607   -1.510  -2.885  1.00 21.07  ? 262 GLY C CA  1 
ATOM   6527  C  C   . GLY C 1 262 ? 9.661   -1.408  -3.995  1.00 22.01  ? 262 GLY C C   1 
ATOM   6528  O  O   . GLY C 1 262 ? 9.461   -0.791  -5.014  1.00 20.16  ? 262 GLY C O   1 
ATOM   6529  N  N   . TYR C 1 263 ? 10.795  -2.073  -3.760  1.00 23.16  ? 263 TYR C N   1 
ATOM   6530  C  CA  . TYR C 1 263 ? 11.893  -2.081  -4.682  1.00 20.52  ? 263 TYR C CA  1 
ATOM   6531  C  C   . TYR C 1 263 ? 11.950  -3.454  -5.323  1.00 23.85  ? 263 TYR C C   1 
ATOM   6532  O  O   . TYR C 1 263 ? 11.708  -4.458  -4.647  1.00 22.28  ? 263 TYR C O   1 
ATOM   6533  C  CB  . TYR C 1 263 ? 13.174  -1.831  -3.904  1.00 21.23  ? 263 TYR C CB  1 
ATOM   6534  C  CG  . TYR C 1 263 ? 13.382  -0.405  -3.420  1.00 20.77  ? 263 TYR C CG  1 
ATOM   6535  C  CD1 . TYR C 1 263 ? 13.993  0.524   -4.215  1.00 19.87  ? 263 TYR C CD1 1 
ATOM   6536  C  CD2 . TYR C 1 263 ? 13.046  -0.036  -2.147  1.00 21.47  ? 263 TYR C CD2 1 
ATOM   6537  C  CE1 . TYR C 1 263 ? 14.246  1.794   -3.767  1.00 22.27  ? 263 TYR C CE1 1 
ATOM   6538  C  CE2 . TYR C 1 263 ? 13.330  1.227   -1.657  1.00 21.38  ? 263 TYR C CE2 1 
ATOM   6539  C  CZ  . TYR C 1 263 ? 13.953  2.133   -2.471  1.00 22.17  ? 263 TYR C CZ  1 
ATOM   6540  O  OH  . TYR C 1 263 ? 14.176  3.421   -2.105  1.00 25.21  ? 263 TYR C OH  1 
ATOM   6541  N  N   . ALA C 1 264 ? 12.267  -3.479  -6.617  1.00 27.00  ? 264 ALA C N   1 
ATOM   6542  C  CA  . ALA C 1 264 ? 12.430  -4.723  -7.362  1.00 24.61  ? 264 ALA C CA  1 
ATOM   6543  C  C   . ALA C 1 264 ? 13.358  -4.501  -8.561  1.00 30.39  ? 264 ALA C C   1 
ATOM   6544  O  O   . ALA C 1 264 ? 13.483  -3.354  -9.041  1.00 28.45  ? 264 ALA C O   1 
ATOM   6545  C  CB  . ALA C 1 264 ? 11.073  -5.189  -7.819  1.00 24.09  ? 264 ALA C CB  1 
ATOM   6546  N  N   . ARG C 1 265 ? 13.969  -5.618  -9.047  1.00 34.26  ? 265 ARG C N   1 
ATOM   6547  C  CA  . ARG C 1 265 ? 14.926  -5.600  -10.143 1.00 33.35  ? 265 ARG C CA  1 
ATOM   6548  C  C   . ARG C 1 265 ? 14.213  -5.301  -11.448 1.00 28.01  ? 265 ARG C C   1 
ATOM   6549  O  O   . ARG C 1 265 ? 14.825  -4.735  -12.341 1.00 33.13  ? 265 ARG C O   1 
ATOM   6550  C  CB  . ARG C 1 265 ? 15.864  -6.804  -10.296 1.00 36.82  ? 265 ARG C CB  1 
ATOM   6551  C  CG  . ARG C 1 265 ? 15.215  -8.026  -10.910 1.00 43.25  ? 265 ARG C CG  1 
ATOM   6552  C  CD  . ARG C 1 265 ? 16.116  -9.284  -10.957 1.00 55.04  ? 265 ARG C CD  1 
ATOM   6553  N  NE  . ARG C 1 265 ? 17.404  -8.983  -11.602 1.00 64.78  ? 265 ARG C NE  1 
ATOM   6554  C  CZ  . ARG C 1 265 ? 18.569  -9.637  -11.508 1.00 53.01  ? 265 ARG C CZ  1 
ATOM   6555  N  NH1 . ARG C 1 265 ? 18.812  -10.548 -10.611 1.00 52.60  ? 265 ARG C NH1 1 
ATOM   6556  N  NH2 . ARG C 1 265 ? 19.543  -9.341  -12.321 1.00 56.03  ? 265 ARG C NH2 1 
ATOM   6557  N  N   . THR C 1 266 ? 12.935  -5.575  -11.530 1.00 26.52  ? 266 THR C N   1 
ATOM   6558  C  CA  . THR C 1 266 ? 12.131  -5.174  -12.672 1.00 32.37  ? 266 THR C CA  1 
ATOM   6559  C  C   . THR C 1 266 ? 10.742  -4.797  -12.158 1.00 28.22  ? 266 THR C C   1 
ATOM   6560  O  O   . THR C 1 266 ? 10.200  -5.474  -11.307 1.00 29.20  ? 266 THR C O   1 
ATOM   6561  C  CB  . THR C 1 266 ? 12.015  -6.326  -13.688 1.00 37.91  ? 266 THR C CB  1 
ATOM   6562  O  OG1 . THR C 1 266 ? 10.891  -6.104  -14.553 1.00 51.79  ? 266 THR C OG1 1 
ATOM   6563  C  CG2 . THR C 1 266 ? 11.617  -7.649  -13.065 1.00 36.10  ? 266 THR C CG2 1 
ATOM   6564  N  N   . PRO C 1 267 ? 10.076  -3.770  -12.705 1.00 28.19  ? 267 PRO C N   1 
ATOM   6565  C  CA  . PRO C 1 267 ? 8.746   -3.440  -12.223 1.00 28.41  ? 267 PRO C CA  1 
ATOM   6566  C  C   . PRO C 1 267 ? 7.669   -4.483  -12.518 1.00 32.02  ? 267 PRO C C   1 
ATOM   6567  O  O   . PRO C 1 267 ? 6.619   -4.426  -11.865 1.00 28.96  ? 267 PRO C O   1 
ATOM   6568  C  CB  . PRO C 1 267 ? 8.457   -2.081  -12.874 1.00 31.63  ? 267 PRO C CB  1 
ATOM   6569  C  CG  . PRO C 1 267 ? 9.427   -1.956  -14.014 1.00 31.79  ? 267 PRO C CG  1 
ATOM   6570  C  CD  . PRO C 1 267 ? 10.587  -2.884  -13.767 1.00 28.87  ? 267 PRO C CD  1 
ATOM   6571  N  N   . GLU C 1 268 ? 7.923   -5.401  -13.489 1.00 39.73  ? 268 GLU C N   1 
ATOM   6572  C  CA  . GLU C 1 268 ? 6.956   -6.448  -13.870 1.00 42.47  ? 268 GLU C CA  1 
ATOM   6573  C  C   . GLU C 1 268 ? 6.522   -7.211  -12.571 1.00 38.22  ? 268 GLU C C   1 
ATOM   6574  O  O   . GLU C 1 268 ? 5.356   -7.557  -12.363 1.00 30.10  ? 268 GLU C O   1 
ATOM   6575  C  CB  . GLU C 1 268 ? 7.368   -7.365  -15.062 1.00 41.77  ? 268 GLU C CB  1 
ATOM   6576  C  CG  . GLU C 1 268 ? 8.170   -6.821  -16.262 1.00 45.34  ? 268 GLU C CG  1 
ATOM   6577  N  N   . VAL C 1 269 ? 7.442   -7.472  -11.622 1.00 31.15  ? 269 VAL C N   1 
ATOM   6578  C  CA  . VAL C 1 269 ? 7.082   -8.236  -10.424 1.00 29.74  ? 269 VAL C CA  1 
ATOM   6579  C  C   . VAL C 1 269 ? 6.082   -7.430  -9.598  1.00 30.83  ? 269 VAL C C   1 
ATOM   6580  O  O   . VAL C 1 269 ? 5.026   -7.914  -9.233  1.00 29.75  ? 269 VAL C O   1 
ATOM   6581  C  CB  . VAL C 1 269 ? 8.365   -8.545  -9.617  1.00 29.59  ? 269 VAL C CB  1 
ATOM   6582  C  CG1 . VAL C 1 269 ? 8.091   -9.200  -8.290  1.00 32.11  ? 269 VAL C CG1 1 
ATOM   6583  C  CG2 . VAL C 1 269 ? 9.350   -9.396  -10.389 1.00 31.07  ? 269 VAL C CG2 1 
ATOM   6584  N  N   . THR C 1 270 ? 6.439   -6.172  -9.288  1.00 35.48  ? 270 THR C N   1 
ATOM   6585  C  CA  . THR C 1 270 ? 5.609   -5.302  -8.469  1.00 33.09  ? 270 THR C CA  1 
ATOM   6586  C  C   . THR C 1 270 ? 4.244   -5.120  -9.142  1.00 31.93  ? 270 THR C C   1 
ATOM   6587  O  O   . THR C 1 270 ? 3.194   -5.119  -8.483  1.00 30.37  ? 270 THR C O   1 
ATOM   6588  C  CB  . THR C 1 270 ? 6.326   -3.959  -8.225  1.00 32.74  ? 270 THR C CB  1 
ATOM   6589  O  OG1 . THR C 1 270 ? 7.649   -4.255  -7.810  1.00 28.00  ? 270 THR C OG1 1 
ATOM   6590  C  CG2 . THR C 1 270 ? 5.660   -3.173  -7.116  1.00 28.99  ? 270 THR C CG2 1 
ATOM   6591  N  N   . GLU C 1 271 ? 4.260   -4.925  -10.470 1.00 32.38  ? 271 GLU C N   1 
ATOM   6592  C  CA  . GLU C 1 271 ? 3.031   -4.643  -11.214 1.00 31.42  ? 271 GLU C CA  1 
ATOM   6593  C  C   . GLU C 1 271 ? 2.100   -5.872  -11.237 1.00 29.52  ? 271 GLU C C   1 
ATOM   6594  O  O   . GLU C 1 271 ? 0.885   -5.751  -11.197 1.00 29.03  ? 271 GLU C O   1 
ATOM   6595  C  CB  . GLU C 1 271 ? 3.363   -4.142  -12.626 1.00 31.88  ? 271 GLU C CB  1 
ATOM   6596  C  CG  . GLU C 1 271 ? 3.776   -2.675  -12.665 1.00 32.36  ? 271 GLU C CG  1 
ATOM   6597  C  CD  . GLU C 1 271 ? 4.527   -2.199  -13.883 1.00 34.27  ? 271 GLU C CD  1 
ATOM   6598  O  OE1 . GLU C 1 271 ? 4.835   -3.003  -14.722 1.00 33.90  ? 271 GLU C OE1 1 
ATOM   6599  O  OE2 . GLU C 1 271 ? 4.890   -1.059  -13.976 1.00 34.85  ? 271 GLU C OE2 1 
ATOM   6600  N  N   . THR C 1 272 ? 2.650   -7.074  -11.263 1.00 27.26  ? 272 THR C N   1 
ATOM   6601  C  CA  . THR C 1 272 ? 1.822   -8.261  -11.195 1.00 29.20  ? 272 THR C CA  1 
ATOM   6602  C  C   . THR C 1 272 ? 1.106   -8.322  -9.853  1.00 31.07  ? 272 THR C C   1 
ATOM   6603  O  O   . THR C 1 272 ? -0.082  -8.664  -9.789  1.00 33.38  ? 272 THR C O   1 
ATOM   6604  C  CB  . THR C 1 272 ? 2.711   -9.487  -11.300 1.00 31.49  ? 272 THR C CB  1 
ATOM   6605  O  OG1 . THR C 1 272 ? 3.212   -9.385  -12.613 1.00 32.19  ? 272 THR C OG1 1 
ATOM   6606  C  CG2 . THR C 1 272 ? 1.992   -10.784 -10.996 1.00 31.02  ? 272 THR C CG2 1 
ATOM   6607  N  N   . MET C 1 273 ? 1.851   -8.051  -8.768  1.00 28.27  ? 273 MET C N   1 
ATOM   6608  C  CA  . MET C 1 273 ? 1.245   -8.070  -7.445  1.00 26.59  ? 273 MET C CA  1 
ATOM   6609  C  C   . MET C 1 273 ? 0.095   -7.060  -7.401  1.00 28.03  ? 273 MET C C   1 
ATOM   6610  O  O   . MET C 1 273 ? -0.983  -7.320  -6.876  1.00 27.43  ? 273 MET C O   1 
ATOM   6611  C  CB  . MET C 1 273 ? 2.303   -7.750  -6.403  1.00 27.29  ? 273 MET C CB  1 
ATOM   6612  C  CG  . MET C 1 273 ? 3.328   -8.846  -6.223  1.00 29.38  ? 273 MET C CG  1 
ATOM   6613  S  SD  . MET C 1 273 ? 4.608   -8.375  -5.042  1.00 30.45  ? 273 MET C SD  1 
ATOM   6614  C  CE  . MET C 1 273 ? 5.634   -9.841  -4.988  1.00 26.79  ? 273 MET C CE  1 
ATOM   6615  N  N   . LEU C 1 274 ? 0.331   -5.886  -7.988  1.00 29.40  ? 274 LEU C N   1 
ATOM   6616  C  CA  . LEU C 1 274 ? -0.668  -4.839  -8.003  1.00 30.59  ? 274 LEU C CA  1 
ATOM   6617  C  C   . LEU C 1 274 ? -1.911  -5.274  -8.787  1.00 28.16  ? 274 LEU C C   1 
ATOM   6618  O  O   . LEU C 1 274 ? -3.042  -4.969  -8.356  1.00 28.38  ? 274 LEU C O   1 
ATOM   6619  C  CB  . LEU C 1 274 ? -0.109  -3.521  -8.578  1.00 32.11  ? 274 LEU C CB  1 
ATOM   6620  C  CG  . LEU C 1 274 ? 0.820   -2.703  -7.679  1.00 30.87  ? 274 LEU C CG  1 
ATOM   6621  C  CD1 . LEU C 1 274 ? 1.457   -1.572  -8.476  1.00 31.58  ? 274 LEU C CD1 1 
ATOM   6622  C  CD2 . LEU C 1 274 ? 0.066   -2.223  -6.457  1.00 27.45  ? 274 LEU C CD2 1 
ATOM   6623  N  N   . GLU C 1 275 ? -1.703  -5.891  -9.966  1.00 29.76  ? 275 GLU C N   1 
ATOM   6624  C  CA  . GLU C 1 275 ? -2.834  -6.387  -10.758 1.00 33.64  ? 275 GLU C CA  1 
ATOM   6625  C  C   . GLU C 1 275 ? -3.706  -7.381  -9.964  1.00 30.46  ? 275 GLU C C   1 
ATOM   6626  O  O   . GLU C 1 275 ? -4.935  -7.241  -9.887  1.00 28.25  ? 275 GLU C O   1 
ATOM   6627  C  CB  . GLU C 1 275 ? -2.388  -7.112  -12.024 1.00 30.49  ? 275 GLU C CB  1 
ATOM   6628  C  CG  . GLU C 1 275 ? -2.032  -6.125  -13.120 1.00 37.77  ? 275 GLU C CG  1 
ATOM   6629  C  CD  . GLU C 1 275 ? -1.404  -6.822  -14.306 1.00 39.45  ? 275 GLU C CD  1 
ATOM   6630  O  OE1 . GLU C 1 275 ? -1.457  -8.040  -14.308 1.00 44.37  ? 275 GLU C OE1 1 
ATOM   6631  O  OE2 . GLU C 1 275 ? -0.868  -6.197  -15.215 1.00 49.95  ? 275 GLU C OE2 1 
ATOM   6632  N  N   . ARG C 1 276 ? -3.049  -8.372  -9.350  1.00 27.03  ? 276 ARG C N   1 
ATOM   6633  C  CA  . ARG C 1 276 ? -3.755  -9.316  -8.500  1.00 33.04  ? 276 ARG C CA  1 
ATOM   6634  C  C   . ARG C 1 276 ? -4.575  -8.633  -7.421  1.00 33.00  ? 276 ARG C C   1 
ATOM   6635  O  O   . ARG C 1 276 ? -5.706  -9.040  -7.197  1.00 33.30  ? 276 ARG C O   1 
ATOM   6636  C  CB  . ARG C 1 276 ? -2.782  -10.328 -7.907  1.00 33.91  ? 276 ARG C CB  1 
ATOM   6637  C  CG  . ARG C 1 276 ? -2.396  -11.239 -9.051  1.00 32.41  ? 276 ARG C CG  1 
ATOM   6638  C  CD  . ARG C 1 276 ? -1.098  -11.915 -8.839  1.00 36.46  ? 276 ARG C CD  1 
ATOM   6639  N  NE  . ARG C 1 276 ? -1.093  -12.802 -7.675  1.00 46.05  ? 276 ARG C NE  1 
ATOM   6640  C  CZ  . ARG C 1 276 ? -1.638  -14.008 -7.631  1.00 49.65  ? 276 ARG C CZ  1 
ATOM   6641  N  NH1 . ARG C 1 276 ? -2.047  -14.556 -8.759  1.00 57.55  ? 276 ARG C NH1 1 
ATOM   6642  N  NH2 . ARG C 1 276 ? -1.796  -14.651 -6.487  1.00 42.42  ? 276 ARG C NH2 1 
ATOM   6643  N  N   . MET C 1 277 ? -3.999  -7.627  -6.748  1.00 29.00  ? 277 MET C N   1 
ATOM   6644  C  CA  . MET C 1 277 ? -4.683  -6.958  -5.662  1.00 27.60  ? 277 MET C CA  1 
ATOM   6645  C  C   . MET C 1 277 ? -5.893  -6.181  -6.198  1.00 27.45  ? 277 MET C C   1 
ATOM   6646  O  O   . MET C 1 277 ? -6.962  -6.206  -5.580  1.00 28.08  ? 277 MET C O   1 
ATOM   6647  C  CB  . MET C 1 277 ? -3.727  -5.975  -4.944  1.00 29.71  ? 277 MET C CB  1 
ATOM   6648  C  CG  . MET C 1 277 ? -2.610  -6.594  -4.132  1.00 26.17  ? 277 MET C CG  1 
ATOM   6649  S  SD  . MET C 1 277 ? -1.488  -5.339  -3.440  1.00 24.74  ? 277 MET C SD  1 
ATOM   6650  C  CE  . MET C 1 277 ? -2.610  -4.359  -2.438  1.00 28.28  ? 277 MET C CE  1 
ATOM   6651  N  N   . PHE C 1 278 ? -5.705  -5.397  -7.284  1.00 26.87  ? 278 PHE C N   1 
ATOM   6652  C  CA  . PHE C 1 278 ? -6.750  -4.485  -7.716  1.00 28.28  ? 278 PHE C CA  1 
ATOM   6653  C  C   . PHE C 1 278 ? -7.740  -5.148  -8.691  1.00 29.24  ? 278 PHE C C   1 
ATOM   6654  O  O   . PHE C 1 278 ? -8.938  -4.866  -8.681  1.00 33.15  ? 278 PHE C O   1 
ATOM   6655  C  CB  . PHE C 1 278 ? -6.160  -3.217  -8.343  1.00 27.60  ? 278 PHE C CB  1 
ATOM   6656  C  CG  . PHE C 1 278 ? -5.611  -2.275  -7.287  1.00 24.44  ? 278 PHE C CG  1 
ATOM   6657  C  CD1 . PHE C 1 278 ? -4.330  -2.438  -6.769  1.00 29.41  ? 278 PHE C CD1 1 
ATOM   6658  C  CD2 . PHE C 1 278 ? -6.389  -1.269  -6.788  1.00 23.61  ? 278 PHE C CD2 1 
ATOM   6659  C  CE1 . PHE C 1 278 ? -3.841  -1.585  -5.786  1.00 25.92  ? 278 PHE C CE1 1 
ATOM   6660  C  CE2 . PHE C 1 278 ? -5.913  -0.413  -5.803  1.00 29.95  ? 278 PHE C CE2 1 
ATOM   6661  C  CZ  . PHE C 1 278 ? -4.655  -0.615  -5.258  1.00 25.82  ? 278 PHE C CZ  1 
ATOM   6662  N  N   . LEU C 1 279 ? -7.247  -6.051  -9.530  1.00 30.74  ? 279 LEU C N   1 
ATOM   6663  C  CA  . LEU C 1 279 ? -8.073  -6.613  -10.589 1.00 33.51  ? 279 LEU C CA  1 
ATOM   6664  C  C   . LEU C 1 279 ? -8.527  -8.026  -10.256 1.00 39.09  ? 279 LEU C C   1 
ATOM   6665  O  O   . LEU C 1 279 ? -9.485  -8.487  -10.832 1.00 49.10  ? 279 LEU C O   1 
ATOM   6666  C  CB  . LEU C 1 279 ? -7.297  -6.626  -11.901 1.00 32.79  ? 279 LEU C CB  1 
ATOM   6667  C  CG  . LEU C 1 279 ? -6.799  -5.258  -12.371 1.00 37.70  ? 279 LEU C CG  1 
ATOM   6668  C  CD1 . LEU C 1 279 ? -6.113  -5.465  -13.672 1.00 36.34  ? 279 LEU C CD1 1 
ATOM   6669  C  CD2 . LEU C 1 279 ? -7.839  -4.187  -12.524 1.00 38.93  ? 279 LEU C CD2 1 
ATOM   6670  N  N   . GLY C 1 280 ? -7.851  -8.745  -9.373  1.00 39.76  ? 280 GLY C N   1 
ATOM   6671  C  CA  . GLY C 1 280 ? -8.425  -9.989  -8.916  1.00 37.78  ? 280 GLY C CA  1 
ATOM   6672  C  C   . GLY C 1 280 ? -7.786  -11.145 -9.665  1.00 36.92  ? 280 GLY C C   1 
ATOM   6673  O  O   . GLY C 1 280 ? -6.830  -10.970 -10.418 1.00 35.07  ? 280 GLY C O   1 
ATOM   6674  N  N   . THR C 1 281 ? -8.238  -12.347 -9.306  1.00 42.76  ? 281 THR C N   1 
ATOM   6675  C  CA  . THR C 1 281 ? -7.831  -13.592 -9.944  1.00 40.10  ? 281 THR C CA  1 
ATOM   6676  C  C   . THR C 1 281 ? -9.107  -14.364 -10.224 1.00 45.99  ? 281 THR C C   1 
ATOM   6677  O  O   . THR C 1 281 ? -10.194 -13.837 -9.921  1.00 36.82  ? 281 THR C O   1 
ATOM   6678  C  CB  . THR C 1 281 ? -6.891  -14.424 -9.076  1.00 36.42  ? 281 THR C CB  1 
ATOM   6679  O  OG1 . THR C 1 281 ? -7.643  -14.756 -7.922  1.00 38.91  ? 281 THR C OG1 1 
ATOM   6680  C  CG2 . THR C 1 281 ? -5.660  -13.622 -8.717  1.00 40.27  ? 281 THR C CG2 1 
ATOM   6681  N  N   . ALA C 1 282 ? -8.959  -15.616 -10.725 1.00 50.92  ? 282 ALA C N   1 
ATOM   6682  C  CA  . ALA C 1 282 ? -10.149 -16.441 -10.965 1.00 50.94  ? 282 ALA C CA  1 
ATOM   6683  C  C   . ALA C 1 282 ? -10.915 -16.657 -9.659  1.00 45.67  ? 282 ALA C C   1 
ATOM   6684  O  O   . ALA C 1 282 ? -12.118 -16.530 -9.671  1.00 38.84  ? 282 ALA C O   1 
ATOM   6685  C  CB  . ALA C 1 282 ? -9.797  -17.741 -11.663 1.00 60.36  ? 282 ALA C CB  1 
ATOM   6686  N  N   . SER C 1 283 ? -10.216 -16.886 -8.528  1.00 51.13  ? 283 SER C N   1 
ATOM   6687  C  CA  . SER C 1 283 ? -10.833 -17.184 -7.245  1.00 46.69  ? 283 SER C CA  1 
ATOM   6688  C  C   . SER C 1 283 ? -10.963 -15.998 -6.283  1.00 47.91  ? 283 SER C C   1 
ATOM   6689  O  O   . SER C 1 283 ? -11.305 -16.217 -5.137  1.00 47.65  ? 283 SER C O   1 
ATOM   6690  C  CB  . SER C 1 283 ? -10.025 -18.265 -6.593  1.00 50.70  ? 283 SER C CB  1 
ATOM   6691  O  OG  . SER C 1 283 ? -10.342 -19.524 -7.167  1.00 69.39  ? 283 SER C OG  1 
ATOM   6692  N  N   . ALA C 1 284 ? -10.602 -14.762 -6.644  1.00 48.63  ? 284 ALA C N   1 
ATOM   6693  C  CA  . ALA C 1 284 ? -10.593 -13.687 -5.648  1.00 37.48  ? 284 ALA C CA  1 
ATOM   6694  C  C   . ALA C 1 284 ? -10.894 -12.365 -6.315  1.00 34.16  ? 284 ALA C C   1 
ATOM   6695  O  O   . ALA C 1 284 ? -10.187 -11.937 -7.227  1.00 38.68  ? 284 ALA C O   1 
ATOM   6696  C  CB  . ALA C 1 284 ? -9.253  -13.618 -4.945  1.00 39.18  ? 284 ALA C CB  1 
ATOM   6697  N  N   . PRO C 1 285 ? -12.005 -11.703 -5.966  1.00 31.32  ? 285 PRO C N   1 
ATOM   6698  C  CA  . PRO C 1 285 ? -12.371 -10.454 -6.633  1.00 32.30  ? 285 PRO C CA  1 
ATOM   6699  C  C   . PRO C 1 285 ? -11.335 -9.326  -6.541  1.00 40.58  ? 285 PRO C C   1 
ATOM   6700  O  O   . PRO C 1 285 ? -11.087 -8.612  -7.502  1.00 38.97  ? 285 PRO C O   1 
ATOM   6701  C  CB  . PRO C 1 285 ? -13.704 -10.053 -5.950  1.00 35.01  ? 285 PRO C CB  1 
ATOM   6702  C  CG  . PRO C 1 285 ? -13.749 -10.849 -4.671  1.00 38.46  ? 285 PRO C CG  1 
ATOM   6703  C  CD  . PRO C 1 285 ? -12.959 -12.128 -4.943  1.00 34.25  ? 285 PRO C CD  1 
ATOM   6704  N  N   . HIS C 1 286 ? -10.743 -9.141  -5.353  1.00 45.80  ? 286 HIS C N   1 
ATOM   6705  C  CA  . HIS C 1 286 ? -9.700  -8.149  -5.108  1.00 37.08  ? 286 HIS C CA  1 
ATOM   6706  C  C   . HIS C 1 286 ? -9.128  -8.411  -3.731  1.00 33.92  ? 286 HIS C C   1 
ATOM   6707  O  O   . HIS C 1 286 ? -9.707  -9.186  -2.992  1.00 41.18  ? 286 HIS C O   1 
ATOM   6708  C  CB  . HIS C 1 286 ? -10.262 -6.745  -5.214  1.00 30.54  ? 286 HIS C CB  1 
ATOM   6709  C  CG  . HIS C 1 286 ? -11.342 -6.501  -4.264  1.00 31.81  ? 286 HIS C CG  1 
ATOM   6710  N  ND1 . HIS C 1 286 ? -12.628 -6.343  -4.691  1.00 36.18  ? 286 HIS C ND1 1 
ATOM   6711  C  CD2 . HIS C 1 286 ? -11.379 -6.280  -2.945  1.00 38.13  ? 286 HIS C CD2 1 
ATOM   6712  C  CE1 . HIS C 1 286 ? -13.378 -5.984  -3.637  1.00 33.20  ? 286 HIS C CE1 1 
ATOM   6713  N  NE2 . HIS C 1 286 ? -12.660 -5.950  -2.564  1.00 30.64  ? 286 HIS C NE2 1 
ATOM   6714  N  N   . ASP C 1 287 ? -7.983  -7.807  -3.414  1.00 33.81  ? 287 ASP C N   1 
ATOM   6715  C  CA  . ASP C 1 287 ? -7.342  -7.963  -2.104  1.00 32.03  ? 287 ASP C CA  1 
ATOM   6716  C  C   . ASP C 1 287 ? -8.216  -7.293  -1.043  1.00 30.48  ? 287 ASP C C   1 
ATOM   6717  O  O   . ASP C 1 287 ? -8.501  -6.082  -1.101  1.00 28.95  ? 287 ASP C O   1 
ATOM   6718  C  CB  . ASP C 1 287 ? -5.947  -7.356  -2.146  1.00 31.09  ? 287 ASP C CB  1 
ATOM   6719  C  CG  . ASP C 1 287 ? -5.066  -7.565  -0.927  1.00 29.66  ? 287 ASP C CG  1 
ATOM   6720  O  OD1 . ASP C 1 287 ? -5.610  -7.757  0.189   1.00 30.64  ? 287 ASP C OD1 1 
ATOM   6721  O  OD2 . ASP C 1 287 ? -3.849  -7.590  -1.117  1.00 27.77  ? 287 ASP C OD2 1 
ATOM   6722  N  N   . ARG C 1 288 ? -8.640  -8.065  -0.036  1.00 28.23  ? 288 ARG C N   1 
ATOM   6723  C  CA  . ARG C 1 288 ? -9.527  -7.521  0.997   1.00 28.86  ? 288 ARG C CA  1 
ATOM   6724  C  C   . ARG C 1 288 ? -8.923  -6.306  1.727   1.00 25.85  ? 288 ARG C C   1 
ATOM   6725  O  O   . ARG C 1 288 ? -9.650  -5.509  2.327   1.00 23.84  ? 288 ARG C O   1 
ATOM   6726  C  CB  . ARG C 1 288 ? -9.835  -8.646  1.993   1.00 33.47  ? 288 ARG C CB  1 
ATOM   6727  C  CG  . ARG C 1 288 ? -10.849 -9.637  1.434   1.00 39.44  ? 288 ARG C CG  1 
ATOM   6728  C  CD  . ARG C 1 288 ? -12.266 -9.039  1.598   1.00 38.12  ? 288 ARG C CD  1 
ATOM   6729  N  NE  . ARG C 1 288 ? -12.811 -9.160  2.963   1.00 38.36  ? 288 ARG C NE  1 
ATOM   6730  C  CZ  . ARG C 1 288 ? -13.433 -8.206  3.675   1.00 40.77  ? 288 ARG C CZ  1 
ATOM   6731  N  NH1 . ARG C 1 288 ? -13.540 -6.965  3.200   1.00 39.11  ? 288 ARG C NH1 1 
ATOM   6732  N  NH2 . ARG C 1 288 ? -13.959 -8.486  4.870   1.00 36.16  ? 288 ARG C NH2 1 
ATOM   6733  N  N   . ILE C 1 289 ? -7.583  -6.152  1.716   1.00 24.51  ? 289 ILE C N   1 
ATOM   6734  C  CA  . ILE C 1 289 ? -6.993  -5.061  2.463   1.00 25.44  ? 289 ILE C CA  1 
ATOM   6735  C  C   . ILE C 1 289 ? -7.457  -3.756  1.858   1.00 22.45  ? 289 ILE C C   1 
ATOM   6736  O  O   . ILE C 1 289 ? -7.484  -2.756  2.566   1.00 22.92  ? 289 ILE C O   1 
ATOM   6737  C  CB  . ILE C 1 289 ? -5.454  -5.178  2.478   1.00 29.88  ? 289 ILE C CB  1 
ATOM   6738  C  CG1 . ILE C 1 289 ? -4.878  -4.566  3.765   1.00 29.69  ? 289 ILE C CG1 1 
ATOM   6739  C  CG2 . ILE C 1 289 ? -4.775  -4.611  1.195   1.00 27.11  ? 289 ILE C CG2 1 
ATOM   6740  C  CD1 . ILE C 1 289 ? -3.379  -4.861  3.941   1.00 35.41  ? 289 ILE C CD1 1 
ATOM   6741  N  N   . LEU C 1 290 ? -7.836  -3.777  0.563   1.00 25.48  ? 290 LEU C N   1 
ATOM   6742  C  CA  . LEU C 1 290 ? -8.249  -2.546  -0.134  1.00 29.37  ? 290 LEU C CA  1 
ATOM   6743  C  C   . LEU C 1 290 ? -9.638  -2.082  0.287   1.00 27.04  ? 290 LEU C C   1 
ATOM   6744  O  O   . LEU C 1 290 ? -10.046 -0.941  0.066   1.00 26.39  ? 290 LEU C O   1 
ATOM   6745  C  CB  . LEU C 1 290 ? -8.152  -2.762  -1.639  1.00 30.73  ? 290 LEU C CB  1 
ATOM   6746  C  CG  . LEU C 1 290 ? -6.737  -3.000  -2.186  1.00 27.71  ? 290 LEU C CG  1 
ATOM   6747  C  CD1 . LEU C 1 290 ? -6.789  -3.364  -3.657  1.00 28.92  ? 290 LEU C CD1 1 
ATOM   6748  C  CD2 . LEU C 1 290 ? -5.845  -1.767  -1.969  1.00 26.27  ? 290 LEU C CD2 1 
ATOM   6749  N  N   . ASP C 1 291 ? -10.371 -2.977  0.940   1.00 27.81  ? 291 ASP C N   1 
ATOM   6750  C  CA  . ASP C 1 291 ? -11.632 -2.553  1.537   1.00 32.38  ? 291 ASP C CA  1 
ATOM   6751  C  C   . ASP C 1 291 ? -11.416 -1.646  2.741   1.00 27.51  ? 291 ASP C C   1 
ATOM   6752  O  O   . ASP C 1 291 ? -12.391 -1.115  3.208   1.00 24.21  ? 291 ASP C O   1 
ATOM   6753  C  CB  . ASP C 1 291 ? -12.583 -3.721  1.842   1.00 35.12  ? 291 ASP C CB  1 
ATOM   6754  C  CG  . ASP C 1 291 ? -13.076 -4.489  0.619   1.00 32.69  ? 291 ASP C CG  1 
ATOM   6755  O  OD1 . ASP C 1 291 ? -13.201 -3.916  -0.474  1.00 34.80  ? 291 ASP C OD1 1 
ATOM   6756  O  OD2 . ASP C 1 291 ? -13.183 -5.691  0.747   1.00 38.29  ? 291 ASP C OD2 1 
ATOM   6757  N  N   . PHE C 1 292 ? -10.178 -1.512  3.253   1.00 28.05  ? 292 PHE C N   1 
ATOM   6758  C  CA  . PHE C 1 292 ? -9.898  -0.575  4.335   1.00 25.97  ? 292 PHE C CA  1 
ATOM   6759  C  C   . PHE C 1 292 ? -8.750  0.347   3.976   1.00 28.04  ? 292 PHE C C   1 
ATOM   6760  O  O   . PHE C 1 292 ? -8.220  0.956   4.866   1.00 27.65  ? 292 PHE C O   1 
ATOM   6761  C  CB  . PHE C 1 292 ? -9.518  -1.402  5.560   1.00 26.00  ? 292 PHE C CB  1 
ATOM   6762  C  CG  . PHE C 1 292 ? -10.537 -2.473  5.865   1.00 24.90  ? 292 PHE C CG  1 
ATOM   6763  C  CD1 . PHE C 1 292 ? -11.660 -2.153  6.603   1.00 29.31  ? 292 PHE C CD1 1 
ATOM   6764  C  CD2 . PHE C 1 292 ? -10.436 -3.751  5.341   1.00 27.46  ? 292 PHE C CD2 1 
ATOM   6765  C  CE1 . PHE C 1 292 ? -12.624 -3.102  6.859   1.00 24.01  ? 292 PHE C CE1 1 
ATOM   6766  C  CE2 . PHE C 1 292 ? -11.407 -4.727  5.642   1.00 25.98  ? 292 PHE C CE2 1 
ATOM   6767  C  CZ  . PHE C 1 292 ? -12.472 -4.394  6.399   1.00 21.66  ? 292 PHE C CZ  1 
ATOM   6768  N  N   . SER C 1 293 ? -8.298  0.373   2.727   1.00 28.67  ? 293 SER C N   1 
ATOM   6769  C  CA  . SER C 1 293 ? -7.109  1.127   2.347   1.00 26.79  ? 293 SER C CA  1 
ATOM   6770  C  C   . SER C 1 293 ? -7.310  1.721   0.969   1.00 24.87  ? 293 SER C C   1 
ATOM   6771  O  O   . SER C 1 293 ? -7.562  1.011   0.016   1.00 28.48  ? 293 SER C O   1 
ATOM   6772  C  CB  . SER C 1 293 ? -5.900  0.250   2.308   1.00 22.35  ? 293 SER C CB  1 
ATOM   6773  O  OG  . SER C 1 293 ? -5.884  -0.586  3.447   1.00 29.34  ? 293 SER C OG  1 
ATOM   6774  N  N   . THR C 1 294 ? -7.161  3.021   0.860   1.00 26.95  ? 294 THR C N   1 
ATOM   6775  C  CA  . THR C 1 294 ? -7.339  3.745   -0.400  1.00 28.91  ? 294 THR C CA  1 
ATOM   6776  C  C   . THR C 1 294 ? -5.993  4.342   -0.815  1.00 28.67  ? 294 THR C C   1 
ATOM   6777  O  O   . THR C 1 294 ? -5.431  5.114   -0.019  1.00 26.24  ? 294 THR C O   1 
ATOM   6778  C  CB  . THR C 1 294 ? -8.284  4.922   -0.130  1.00 25.66  ? 294 THR C CB  1 
ATOM   6779  O  OG1 . THR C 1 294 ? -9.469  4.335   0.359   1.00 31.27  ? 294 THR C OG1 1 
ATOM   6780  C  CG2 . THR C 1 294 ? -8.551  5.794   -1.326  1.00 24.68  ? 294 THR C CG2 1 
ATOM   6781  N  N   . ALA C 1 295 ? -5.554  4.078   -2.064  1.00 28.23  ? 295 ALA C N   1 
ATOM   6782  C  CA  . ALA C 1 295 ? -4.322  4.629   -2.612  1.00 23.18  ? 295 ALA C CA  1 
ATOM   6783  C  C   . ALA C 1 295 ? -4.617  6.029   -3.045  1.00 24.35  ? 295 ALA C C   1 
ATOM   6784  O  O   . ALA C 1 295 ? -5.567  6.195   -3.732  1.00 28.18  ? 295 ALA C O   1 
ATOM   6785  C  CB  . ALA C 1 295 ? -3.912  3.818   -3.806  1.00 25.33  ? 295 ALA C CB  1 
ATOM   6786  N  N   . VAL C 1 296 ? -3.853  7.032   -2.681  1.00 27.09  ? 296 VAL C N   1 
ATOM   6787  C  CA  . VAL C 1 296 ? -4.103  8.390   -3.177  1.00 26.02  ? 296 VAL C CA  1 
ATOM   6788  C  C   . VAL C 1 296 ? -2.896  8.914   -3.971  1.00 24.40  ? 296 VAL C C   1 
ATOM   6789  O  O   . VAL C 1 296 ? -2.943  10.026  -4.452  1.00 25.60  ? 296 VAL C O   1 
ATOM   6790  C  CB  . VAL C 1 296 ? -4.515  9.364   -2.053  1.00 26.22  ? 296 VAL C CB  1 
ATOM   6791  C  CG1 . VAL C 1 296 ? -5.607  8.797   -1.198  1.00 28.10  ? 296 VAL C CG1 1 
ATOM   6792  C  CG2 . VAL C 1 296 ? -3.389  9.648   -1.116  1.00 27.66  ? 296 VAL C CG2 1 
ATOM   6793  N  N   . THR C 1 297 ? -1.800  8.162   -4.061  1.00 20.60  ? 297 THR C N   1 
ATOM   6794  C  CA  . THR C 1 297 ? -0.735  8.509   -4.967  1.00 19.10  ? 297 THR C CA  1 
ATOM   6795  C  C   . THR C 1 297 ? -0.254  7.223   -5.586  1.00 22.25  ? 297 THR C C   1 
ATOM   6796  O  O   . THR C 1 297 ? -0.537  6.138   -5.081  1.00 23.53  ? 297 THR C O   1 
ATOM   6797  C  CB  . THR C 1 297 ? 0.455   9.186   -4.293  1.00 22.27  ? 297 THR C CB  1 
ATOM   6798  O  OG1 . THR C 1 297 ? 1.200   8.307   -3.454  1.00 21.98  ? 297 THR C OG1 1 
ATOM   6799  C  CG2 . THR C 1 297 ? 0.087   10.428  -3.512  1.00 24.69  ? 297 THR C CG2 1 
ATOM   6800  N  N   . GLY C 1 298 ? 0.519   7.370   -6.658  1.00 24.32  ? 298 GLY C N   1 
ATOM   6801  C  CA  . GLY C 1 298 ? 1.109   6.208   -7.301  1.00 26.44  ? 298 GLY C CA  1 
ATOM   6802  C  C   . GLY C 1 298 ? 2.172   6.673   -8.306  1.00 25.85  ? 298 GLY C C   1 
ATOM   6803  O  O   . GLY C 1 298 ? 1.879   7.467   -9.192  1.00 26.96  ? 298 GLY C O   1 
ATOM   6804  N  N   . SER C 1 299 ? 3.420   6.215   -8.144  1.00 21.58  ? 299 SER C N   1 
ATOM   6805  C  CA  . SER C 1 299 ? 4.465   6.608   -9.041  1.00 21.20  ? 299 SER C CA  1 
ATOM   6806  C  C   . SER C 1 299 ? 5.478   5.495   -9.095  1.00 22.62  ? 299 SER C C   1 
ATOM   6807  O  O   . SER C 1 299 ? 5.598   4.721   -8.156  1.00 23.13  ? 299 SER C O   1 
ATOM   6808  C  CB  . SER C 1 299 ? 5.098   7.917   -8.615  1.00 23.88  ? 299 SER C CB  1 
ATOM   6809  O  OG  . SER C 1 299 ? 4.144   8.910   -8.230  1.00 25.28  ? 299 SER C OG  1 
ATOM   6810  N  N   . LEU C 1 300 ? 6.233   5.495   -10.188 1.00 21.85  ? 300 LEU C N   1 
ATOM   6811  C  CA  . LEU C 1 300 ? 7.293   4.531   -10.404 1.00 24.38  ? 300 LEU C CA  1 
ATOM   6812  C  C   . LEU C 1 300 ? 8.582   5.310   -10.731 1.00 24.75  ? 300 LEU C C   1 
ATOM   6813  O  O   . LEU C 1 300 ? 8.567   6.252   -11.509 1.00 26.70  ? 300 LEU C O   1 
ATOM   6814  C  CB  . LEU C 1 300 ? 6.827   3.600   -11.522 1.00 23.87  ? 300 LEU C CB  1 
ATOM   6815  C  CG  . LEU C 1 300 ? 7.741   2.414   -11.864 1.00 29.66  ? 300 LEU C CG  1 
ATOM   6816  C  CD1 . LEU C 1 300 ? 7.084   1.642   -12.970 1.00 34.84  ? 300 LEU C CD1 1 
ATOM   6817  C  CD2 . LEU C 1 300 ? 9.045   2.753   -12.449 1.00 32.74  ? 300 LEU C CD2 1 
ATOM   6818  N  N   . PHE C 1 301 ? 9.696   4.883   -10.151 1.00 22.42  ? 301 PHE C N   1 
ATOM   6819  C  CA  . PHE C 1 301 ? 10.985  5.498   -10.370 1.00 23.49  ? 301 PHE C CA  1 
ATOM   6820  C  C   . PHE C 1 301 ? 12.057  4.435   -10.558 1.00 22.38  ? 301 PHE C C   1 
ATOM   6821  O  O   . PHE C 1 301 ? 11.965  3.352   -10.009 1.00 24.97  ? 301 PHE C O   1 
ATOM   6822  C  CB  . PHE C 1 301 ? 11.401  6.305   -9.132  1.00 22.86  ? 301 PHE C CB  1 
ATOM   6823  C  CG  . PHE C 1 301 ? 10.384  7.312   -8.673  1.00 19.83  ? 301 PHE C CG  1 
ATOM   6824  C  CD1 . PHE C 1 301 ? 10.393  8.583   -9.203  1.00 22.45  ? 301 PHE C CD1 1 
ATOM   6825  C  CD2 . PHE C 1 301 ? 9.394   6.965   -7.794  1.00 19.55  ? 301 PHE C CD2 1 
ATOM   6826  C  CE1 . PHE C 1 301 ? 9.449   9.518   -8.794  1.00 22.99  ? 301 PHE C CE1 1 
ATOM   6827  C  CE2 . PHE C 1 301 ? 8.478   7.890   -7.362  1.00 20.52  ? 301 PHE C CE2 1 
ATOM   6828  C  CZ  . PHE C 1 301 ? 8.500   9.168   -7.879  1.00 23.37  ? 301 PHE C CZ  1 
ATOM   6829  N  N   . PHE C 1 302 ? 13.108  4.846   -11.255 1.00 21.49  ? 302 PHE C N   1 
ATOM   6830  C  CA  . PHE C 1 302 ? 14.360  4.121   -11.353 1.00 20.86  ? 302 PHE C CA  1 
ATOM   6831  C  C   . PHE C 1 302 ? 15.376  4.782   -10.433 1.00 19.36  ? 302 PHE C C   1 
ATOM   6832  O  O   . PHE C 1 302 ? 15.576  5.982   -10.498 1.00 20.50  ? 302 PHE C O   1 
ATOM   6833  C  CB  . PHE C 1 302 ? 14.871  4.111   -12.799 1.00 22.75  ? 302 PHE C CB  1 
ATOM   6834  C  CG  . PHE C 1 302 ? 16.111  3.250   -12.980 1.00 24.10  ? 302 PHE C CG  1 
ATOM   6835  C  CD1 . PHE C 1 302 ? 16.039  1.857   -12.883 1.00 29.40  ? 302 PHE C CD1 1 
ATOM   6836  C  CD2 . PHE C 1 302 ? 17.357  3.828   -13.167 1.00 25.98  ? 302 PHE C CD2 1 
ATOM   6837  C  CE1 . PHE C 1 302 ? 17.188  1.073   -12.967 1.00 27.70  ? 302 PHE C CE1 1 
ATOM   6838  C  CE2 . PHE C 1 302 ? 18.498  3.039   -13.233 1.00 27.22  ? 302 PHE C CE2 1 
ATOM   6839  C  CZ  . PHE C 1 302 ? 18.399  1.671   -13.146 1.00 24.61  ? 302 PHE C CZ  1 
ATOM   6840  N  N   . THR C 1 303 ? 16.015  3.977   -9.584  1.00 20.86  ? 303 THR C N   1 
ATOM   6841  C  CA  . THR C 1 303 ? 17.016  4.411   -8.649  1.00 20.83  ? 303 THR C CA  1 
ATOM   6842  C  C   . THR C 1 303 ? 18.354  3.902   -9.170  1.00 23.16  ? 303 THR C C   1 
ATOM   6843  O  O   . THR C 1 303 ? 18.750  2.765   -8.932  1.00 27.48  ? 303 THR C O   1 
ATOM   6844  C  CB  . THR C 1 303 ? 16.762  3.909   -7.226  1.00 21.05  ? 303 THR C CB  1 
ATOM   6845  O  OG1 . THR C 1 303 ? 16.757  2.496   -7.074  1.00 22.93  ? 303 THR C OG1 1 
ATOM   6846  C  CG2 . THR C 1 303 ? 15.417  4.313   -6.707  1.00 23.11  ? 303 THR C CG2 1 
ATOM   6847  N  N   . PRO C 1 304 ? 19.117  4.736   -9.863  1.00 23.74  ? 304 PRO C N   1 
ATOM   6848  C  CA  . PRO C 1 304 ? 20.373  4.322   -10.449 1.00 28.62  ? 304 PRO C CA  1 
ATOM   6849  C  C   . PRO C 1 304 ? 21.412  3.915   -9.424  1.00 32.66  ? 304 PRO C C   1 
ATOM   6850  O  O   . PRO C 1 304 ? 21.327  4.277   -8.251  1.00 38.97  ? 304 PRO C O   1 
ATOM   6851  C  CB  . PRO C 1 304 ? 20.881  5.530   -11.215 1.00 28.96  ? 304 PRO C CB  1 
ATOM   6852  C  CG  . PRO C 1 304 ? 19.964  6.676   -10.953 1.00 29.54  ? 304 PRO C CG  1 
ATOM   6853  C  CD  . PRO C 1 304 ? 18.836  6.161   -10.088 1.00 28.89  ? 304 PRO C CD  1 
ATOM   6854  N  N   . ALA C 1 305 ? 22.433  3.187   -9.907  1.00 35.18  ? 305 ALA C N   1 
ATOM   6855  C  CA  . ALA C 1 305 ? 23.627  2.975   -9.114  1.00 31.81  ? 305 ALA C CA  1 
ATOM   6856  C  C   . ALA C 1 305 ? 24.245  4.321   -8.710  1.00 26.70  ? 305 ALA C C   1 
ATOM   6857  O  O   . ALA C 1 305 ? 24.124  5.330   -9.374  1.00 26.25  ? 305 ALA C O   1 
ATOM   6858  C  CB  . ALA C 1 305 ? 24.556  2.135   -9.917  1.00 33.60  ? 305 ALA C CB  1 
ATOM   6859  N  N   . ALA C 1 306 ? 24.891  4.319   -7.557  1.00 29.23  ? 306 ALA C N   1 
ATOM   6860  C  CA  . ALA C 1 306 ? 25.502  5.500   -6.980  1.00 28.32  ? 306 ALA C CA  1 
ATOM   6861  C  C   . ALA C 1 306 ? 26.519  6.136   -7.924  1.00 33.90  ? 306 ALA C C   1 
ATOM   6862  O  O   . ALA C 1 306 ? 26.534  7.365   -8.034  1.00 31.32  ? 306 ALA C O   1 
ATOM   6863  C  CB  . ALA C 1 306 ? 26.102  5.170   -5.663  1.00 29.51  ? 306 ALA C CB  1 
ATOM   6864  N  N   . ASP C 1 307 ? 27.299  5.321   -8.660  1.00 39.43  ? 307 ASP C N   1 
ATOM   6865  C  CA  . ASP C 1 307 ? 28.338  5.884   -9.531  1.00 45.40  ? 307 ASP C CA  1 
ATOM   6866  C  C   . ASP C 1 307 ? 27.700  6.575   -10.719 1.00 43.61  ? 307 ASP C C   1 
ATOM   6867  O  O   . ASP C 1 307 ? 28.262  7.584   -11.150 1.00 43.10  ? 307 ASP C O   1 
ATOM   6868  C  CB  . ASP C 1 307 ? 29.423  4.941   -10.043 1.00 53.65  ? 307 ASP C CB  1 
ATOM   6869  C  CG  . ASP C 1 307 ? 29.232  3.467   -9.782  1.00 59.20  ? 307 ASP C CG  1 
ATOM   6870  O  OD1 . ASP C 1 307 ? 28.327  2.859   -10.394 1.00 58.36  ? 307 ASP C OD1 1 
ATOM   6871  O  OD2 . ASP C 1 307 ? 29.992  2.985   -8.937  1.00 76.30  ? 307 ASP C OD2 1 
ATOM   6872  N  N   . PHE C 1 308 ? 26.528  6.080   -11.185 1.00 34.72  ? 308 PHE C N   1 
ATOM   6873  C  CA  . PHE C 1 308 ? 25.823  6.788   -12.231 1.00 30.64  ? 308 PHE C CA  1 
ATOM   6874  C  C   . PHE C 1 308 ? 25.622  8.268   -11.846 1.00 35.13  ? 308 PHE C C   1 
ATOM   6875  O  O   . PHE C 1 308 ? 25.825  9.206   -12.648 1.00 37.75  ? 308 PHE C O   1 
ATOM   6876  C  CB  . PHE C 1 308 ? 24.564  6.016   -12.600 1.00 29.09  ? 308 PHE C CB  1 
ATOM   6877  C  CG  . PHE C 1 308 ? 23.741  6.761   -13.647 1.00 35.24  ? 308 PHE C CG  1 
ATOM   6878  C  CD1 . PHE C 1 308 ? 22.905  7.827   -13.294 1.00 39.49  ? 308 PHE C CD1 1 
ATOM   6879  C  CD2 . PHE C 1 308 ? 23.802  6.411   -14.985 1.00 39.11  ? 308 PHE C CD2 1 
ATOM   6880  C  CE1 . PHE C 1 308 ? 22.161  8.515   -14.247 1.00 38.12  ? 308 PHE C CE1 1 
ATOM   6881  C  CE2 . PHE C 1 308 ? 23.046  7.098   -15.925 1.00 37.30  ? 308 PHE C CE2 1 
ATOM   6882  C  CZ  . PHE C 1 308 ? 22.217  8.136   -15.544 1.00 36.96  ? 308 PHE C CZ  1 
ATOM   6883  N  N   . LEU C 1 309 ? 25.200  8.510   -10.603 1.00 33.96  ? 309 LEU C N   1 
ATOM   6884  C  CA  . LEU C 1 309 ? 24.882  9.872   -10.198 1.00 34.60  ? 309 LEU C CA  1 
ATOM   6885  C  C   . LEU C 1 309 ? 26.153  10.693  -10.000 1.00 36.38  ? 309 LEU C C   1 
ATOM   6886  O  O   . LEU C 1 309 ? 26.131  11.870  -10.344 1.00 36.21  ? 309 LEU C O   1 
ATOM   6887  C  CB  . LEU C 1 309 ? 24.017  9.851   -8.945  1.00 36.14  ? 309 LEU C CB  1 
ATOM   6888  C  CG  . LEU C 1 309 ? 22.680  9.096   -9.042  1.00 36.67  ? 309 LEU C CG  1 
ATOM   6889  C  CD1 . LEU C 1 309 ? 22.158  8.787   -7.676  1.00 37.08  ? 309 LEU C CD1 1 
ATOM   6890  C  CD2 . LEU C 1 309 ? 21.685  9.914   -9.829  1.00 35.48  ? 309 LEU C CD2 1 
ATOM   6891  N  N   . GLU C 1 310 ? 27.212  10.080  -9.423  1.00 39.97  ? 310 GLU C N   1 
ATOM   6892  C  CA  . GLU C 1 310 ? 28.490  10.735  -9.155  1.00 46.13  ? 310 GLU C CA  1 
ATOM   6893  C  C   . GLU C 1 310 ? 29.041  11.379  -10.433 1.00 45.38  ? 310 GLU C C   1 
ATOM   6894  O  O   . GLU C 1 310 ? 29.496  12.509  -10.339 1.00 61.81  ? 310 GLU C O   1 
ATOM   6895  C  CB  . GLU C 1 310 ? 29.463  9.774   -8.471  1.00 54.95  ? 310 GLU C CB  1 
ATOM   6896  C  CG  . GLU C 1 310 ? 30.800  10.367  -8.032  1.00 66.84  ? 310 GLU C CG  1 
ATOM   6897  C  CD  . GLU C 1 310 ? 31.501  9.449   -7.031  1.00 81.31  ? 310 GLU C CD  1 
ATOM   6898  O  OE1 . GLU C 1 310 ? 32.382  8.581   -7.363  1.00 82.00  ? 310 GLU C OE1 1 
ATOM   6899  O  OE2 . GLU C 1 310 ? 31.134  9.636   -5.844  1.00 75.84  ? 310 GLU C OE2 1 
ATOM   6900  N  N   . ASP C 1 311 ? 28.890  10.746  -11.609 1.00 45.07  ? 311 ASP C N   1 
ATOM   6901  C  CA  . ASP C 1 311 ? 29.391  11.270  -12.892 1.00 54.88  ? 311 ASP C CA  1 
ATOM   6902  C  C   . ASP C 1 311 ? 28.410  12.181  -13.660 1.00 61.63  ? 311 ASP C C   1 
ATOM   6903  O  O   . ASP C 1 311 ? 27.809  11.716  -14.618 1.00 78.58  ? 311 ASP C O   1 
ATOM   6904  C  CB  . ASP C 1 311 ? 29.670  10.148  -13.896 1.00 56.55  ? 311 ASP C CB  1 
ATOM   6905  C  CG  . ASP C 1 311 ? 30.355  8.883   -13.373 1.00 71.14  ? 311 ASP C CG  1 
ATOM   6906  O  OD1 . ASP C 1 311 ? 31.238  9.030   -12.454 1.00 65.62  ? 311 ASP C OD1 1 
ATOM   6907  O  OD2 . ASP C 1 311 ? 30.023  7.760   -13.922 1.00 63.55  ? 311 ASP C OD2 1 
ATOM   6908  N  N   . LEU C 1 312 ? 28.246  13.477  -13.309 1.00 71.60  ? 312 LEU C N   1 
ATOM   6909  C  CA  . LEU C 1 312 ? 27.357  14.350  -14.087 1.00 74.77  ? 312 LEU C CA  1 
ATOM   6910  C  C   . LEU C 1 312 ? 27.924  15.782  -14.255 1.00 64.02  ? 312 LEU C C   1 
ATOM   6911  O  O   . LEU C 1 312 ? 29.020  16.050  -13.708 1.00 66.45  ? 312 LEU C O   1 
ATOM   6912  C  CB  . LEU C 1 312 ? 25.937  14.341  -13.489 1.00 89.19  ? 312 LEU C CB  1 
ATOM   6913  C  CG  . LEU C 1 312 ? 25.157  13.005  -13.534 1.00 77.93  ? 312 LEU C CG  1 
ATOM   6914  C  CD1 . LEU C 1 312 ? 23.789  13.116  -12.917 1.00 68.05  ? 312 LEU C CD1 1 
ATOM   6915  C  CD2 . LEU C 1 312 ? 24.981  12.478  -14.944 1.00 70.35  ? 312 LEU C CD2 1 
ATOM   6916  N  N   . GLU D 1 7   ? 41.712  -11.650 -0.828  1.00 115.77 ? 7   GLU D N   1 
ATOM   6917  C  CA  . GLU D 1 7   ? 42.914  -11.199 -0.072  1.00 118.39 ? 7   GLU D CA  1 
ATOM   6918  C  C   . GLU D 1 7   ? 43.643  -12.437 0.539   1.00 109.13 ? 7   GLU D C   1 
ATOM   6919  O  O   . GLU D 1 7   ? 43.197  -13.603 0.489   1.00 75.65  ? 7   GLU D O   1 
ATOM   6920  C  CB  . GLU D 1 7   ? 42.457  -9.969  0.764   1.00 71.85  ? 7   GLU D CB  1 
ATOM   6921  N  N   . PRO D 1 8   ? 44.910  -12.265 0.986   1.00 96.12  ? 8   PRO D N   1 
ATOM   6922  C  CA  . PRO D 1 8   ? 45.347  -12.746 2.298   1.00 86.95  ? 8   PRO D CA  1 
ATOM   6923  C  C   . PRO D 1 8   ? 44.565  -11.832 3.259   1.00 61.49  ? 8   PRO D C   1 
ATOM   6924  O  O   . PRO D 1 8   ? 44.076  -10.803 2.794   1.00 45.87  ? 8   PRO D O   1 
ATOM   6925  C  CB  . PRO D 1 8   ? 46.887  -12.528 2.334   1.00 85.24  ? 8   PRO D CB  1 
ATOM   6926  C  CG  . PRO D 1 8   ? 47.260  -11.836 1.038   1.00 83.57  ? 8   PRO D CG  1 
ATOM   6927  C  CD  . PRO D 1 8   ? 46.000  -11.650 0.219   1.00 95.06  ? 8   PRO D CD  1 
ATOM   6928  N  N   . GLU D 1 9   ? 44.451  -12.198 4.565   1.00 51.11  ? 9   GLU D N   1 
ATOM   6929  C  CA  . GLU D 1 9   ? 43.660  -11.459 5.567   1.00 51.77  ? 9   GLU D CA  1 
ATOM   6930  C  C   . GLU D 1 9   ? 44.567  -10.255 5.965   1.00 54.17  ? 9   GLU D C   1 
ATOM   6931  O  O   . GLU D 1 9   ? 45.743  -10.389 6.376   1.00 51.61  ? 9   GLU D O   1 
ATOM   6932  C  CB  . GLU D 1 9   ? 43.019  -12.288 6.735   1.00 49.88  ? 9   GLU D CB  1 
ATOM   6933  C  CG  . GLU D 1 9   ? 41.566  -11.991 7.177   1.00 41.36  ? 9   GLU D CG  1 
ATOM   6934  N  N   . PRO D 1 10  ? 44.121  -8.996  5.728   1.00 40.59  ? 10  PRO D N   1 
ATOM   6935  C  CA  . PRO D 1 10  ? 44.802  -7.824  6.256   1.00 44.06  ? 10  PRO D CA  1 
ATOM   6936  C  C   . PRO D 1 10  ? 44.587  -7.694  7.761   1.00 46.49  ? 10  PRO D C   1 
ATOM   6937  O  O   . PRO D 1 10  ? 43.665  -8.305  8.314   1.00 36.41  ? 10  PRO D O   1 
ATOM   6938  C  CB  . PRO D 1 10  ? 44.128  -6.677  5.479   1.00 43.20  ? 10  PRO D CB  1 
ATOM   6939  C  CG  . PRO D 1 10  ? 42.734  -7.179  5.257   1.00 41.01  ? 10  PRO D CG  1 
ATOM   6940  C  CD  . PRO D 1 10  ? 43.018  -8.597  4.841   1.00 45.21  ? 10  PRO D CD  1 
ATOM   6941  N  N   . GLN D 1 11  ? 45.457  -6.879  8.395   1.00 42.84  ? 11  GLN D N   1 
ATOM   6942  C  CA  . GLN D 1 11  ? 45.179  -6.381  9.728   1.00 32.70  ? 11  GLN D CA  1 
ATOM   6943  C  C   . GLN D 1 11  ? 43.961  -5.463  9.670   1.00 30.75  ? 11  GLN D C   1 
ATOM   6944  O  O   . GLN D 1 11  ? 43.460  -5.157  8.602   1.00 31.18  ? 11  GLN D O   1 
ATOM   6945  C  CB  . GLN D 1 11  ? 46.407  -5.678  10.273  1.00 28.94  ? 11  GLN D CB  1 
ATOM   6946  C  CG  . GLN D 1 11  ? 47.635  -6.547  10.467  1.00 25.14  ? 11  GLN D CG  1 
ATOM   6947  C  CD  . GLN D 1 11  ? 48.690  -5.718  11.159  1.00 26.76  ? 11  GLN D CD  1 
ATOM   6948  O  OE1 . GLN D 1 11  ? 48.558  -5.253  12.315  1.00 25.49  ? 11  GLN D OE1 1 
ATOM   6949  N  NE2 . GLN D 1 11  ? 49.730  -5.447  10.388  1.00 29.45  ? 11  GLN D NE2 1 
ATOM   6950  N  N   . MET D 1 12  ? 43.513  -4.984  10.825  1.00 33.99  ? 12  MET D N   1 
ATOM   6951  C  CA  . MET D 1 12  ? 42.283  -4.228  10.949  1.00 37.11  ? 12  MET D CA  1 
ATOM   6952  C  C   . MET D 1 12  ? 42.533  -2.775  10.564  1.00 31.73  ? 12  MET D C   1 
ATOM   6953  O  O   . MET D 1 12  ? 42.244  -1.834  11.338  1.00 35.81  ? 12  MET D O   1 
ATOM   6954  C  CB  . MET D 1 12  ? 41.742  -4.309  12.401  1.00 51.64  ? 12  MET D CB  1 
ATOM   6955  C  CG  . MET D 1 12  ? 40.235  -3.928  12.609  1.00 54.80  ? 12  MET D CG  1 
ATOM   6956  S  SD  . MET D 1 12  ? 39.155  -5.054  11.684  1.00 62.98  ? 12  MET D SD  1 
ATOM   6957  C  CE  . MET D 1 12  ? 39.970  -6.671  11.806  1.00 57.94  ? 12  MET D CE  1 
ATOM   6958  N  N   . VAL D 1 13  ? 42.993  -2.569  9.336   1.00 28.64  ? 13  VAL D N   1 
ATOM   6959  C  CA  . VAL D 1 13  ? 43.241  -1.205  8.927   1.00 31.54  ? 13  VAL D CA  1 
ATOM   6960  C  C   . VAL D 1 13  ? 41.911  -0.461  8.814   1.00 35.98  ? 13  VAL D C   1 
ATOM   6961  O  O   . VAL D 1 13  ? 41.822  0.683   9.307   1.00 31.23  ? 13  VAL D O   1 
ATOM   6962  C  CB  . VAL D 1 13  ? 44.055  -1.187  7.636   1.00 33.51  ? 13  VAL D CB  1 
ATOM   6963  C  CG1 . VAL D 1 13  ? 44.156  0.223   7.063   1.00 35.52  ? 13  VAL D CG1 1 
ATOM   6964  C  CG2 . VAL D 1 13  ? 45.451  -1.720  7.926   1.00 40.04  ? 13  VAL D CG2 1 
ATOM   6965  N  N   . LEU D 1 14  ? 40.897  -1.143  8.216   1.00 41.02  ? 14  LEU D N   1 
ATOM   6966  C  CA  . LEU D 1 14  ? 39.536  -0.626  8.058   1.00 43.76  ? 14  LEU D CA  1 
ATOM   6967  C  C   . LEU D 1 14  ? 38.784  -0.928  9.331   1.00 45.80  ? 14  LEU D C   1 
ATOM   6968  O  O   . LEU D 1 14  ? 38.286  -2.002  9.487   1.00 53.62  ? 14  LEU D O   1 
ATOM   6969  C  CB  . LEU D 1 14  ? 38.869  -1.274  6.856   1.00 40.77  ? 14  LEU D CB  1 
ATOM   6970  C  CG  . LEU D 1 14  ? 39.761  -1.200  5.608   1.00 46.55  ? 14  LEU D CG  1 
ATOM   6971  C  CD1 . LEU D 1 14  ? 39.691  -2.288  4.527   1.00 51.95  ? 14  LEU D CD1 1 
ATOM   6972  C  CD2 . LEU D 1 14  ? 39.456  0.142   4.981   1.00 45.15  ? 14  LEU D CD2 1 
ATOM   6973  N  N   . SER D 1 15  ? 38.823  -0.046  10.306  1.00 50.14  ? 15  SER D N   1 
ATOM   6974  C  CA  . SER D 1 15  ? 38.155  -0.336  11.555  1.00 48.73  ? 15  SER D CA  1 
ATOM   6975  C  C   . SER D 1 15  ? 36.883  0.503   11.572  1.00 50.67  ? 15  SER D C   1 
ATOM   6976  O  O   . SER D 1 15  ? 36.851  1.599   11.031  1.00 44.48  ? 15  SER D O   1 
ATOM   6977  C  CB  . SER D 1 15  ? 39.070  -0.106  12.751  1.00 52.29  ? 15  SER D CB  1 
ATOM   6978  O  OG  . SER D 1 15  ? 38.563  0.767   13.760  1.00 53.52  ? 15  SER D OG  1 
ATOM   6979  N  N   . PRO D 1 16  ? 35.767  -0.019  12.113  1.00 59.11  ? 16  PRO D N   1 
ATOM   6980  C  CA  . PRO D 1 16  ? 34.684  0.837   12.576  1.00 54.73  ? 16  PRO D CA  1 
ATOM   6981  C  C   . PRO D 1 16  ? 35.200  2.111   13.228  1.00 54.08  ? 16  PRO D C   1 
ATOM   6982  O  O   . PRO D 1 16  ? 36.341  2.148   13.708  1.00 49.49  ? 16  PRO D O   1 
ATOM   6983  C  CB  . PRO D 1 16  ? 33.982  -0.044  13.667  1.00 63.60  ? 16  PRO D CB  1 
ATOM   6984  C  CG  . PRO D 1 16  ? 34.699  -1.395  13.661  1.00 66.55  ? 16  PRO D CG  1 
ATOM   6985  C  CD  . PRO D 1 16  ? 35.498  -1.453  12.350  1.00 65.29  ? 16  PRO D CD  1 
ATOM   6986  N  N   . LEU D 1 17  ? 34.314  3.114   13.282  1.00 48.85  ? 17  LEU D N   1 
ATOM   6987  C  CA  . LEU D 1 17  ? 34.483  4.294   14.116  1.00 51.31  ? 17  LEU D CA  1 
ATOM   6988  C  C   . LEU D 1 17  ? 34.717  3.774   15.557  1.00 43.42  ? 17  LEU D C   1 
ATOM   6989  O  O   . LEU D 1 17  ? 33.993  2.912   16.041  1.00 41.12  ? 17  LEU D O   1 
ATOM   6990  C  CB  . LEU D 1 17  ? 33.272  5.239   13.890  1.00 39.58  ? 17  LEU D CB  1 
ATOM   6991  N  N   . THR D 1 18  ? 35.793  4.247   16.212  1.00 33.64  ? 18  THR D N   1 
ATOM   6992  C  CA  . THR D 1 18  ? 36.137  3.919   17.588  1.00 31.39  ? 18  THR D CA  1 
ATOM   6993  C  C   . THR D 1 18  ? 36.319  5.234   18.308  1.00 26.29  ? 18  THR D C   1 
ATOM   6994  O  O   . THR D 1 18  ? 36.706  6.167   17.665  1.00 30.21  ? 18  THR D O   1 
ATOM   6995  C  CB  . THR D 1 18  ? 37.422  3.081   17.636  1.00 31.90  ? 18  THR D CB  1 
ATOM   6996  O  OG1 . THR D 1 18  ? 38.432  3.717   16.857  1.00 29.51  ? 18  THR D OG1 1 
ATOM   6997  C  CG2 . THR D 1 18  ? 37.208  1.664   17.139  1.00 31.07  ? 18  THR D CG2 1 
ATOM   6998  N  N   . SER D 1 19  ? 36.097  5.327   19.605  1.00 26.88  ? 19  SER D N   1 
ATOM   6999  C  CA  . SER D 1 19  ? 36.204  6.637   20.249  1.00 29.98  ? 19  SER D CA  1 
ATOM   7000  C  C   . SER D 1 19  ? 37.471  6.820   21.089  1.00 25.14  ? 19  SER D C   1 
ATOM   7001  O  O   . SER D 1 19  ? 37.715  7.879   21.686  1.00 24.22  ? 19  SER D O   1 
ATOM   7002  C  CB  . SER D 1 19  ? 34.964  6.864   21.077  1.00 36.43  ? 19  SER D CB  1 
ATOM   7003  O  OG  . SER D 1 19  ? 34.487  5.564   21.314  1.00 44.30  ? 19  SER D OG  1 
ATOM   7004  N  N   . ALA D 1 20  ? 38.308  5.788   21.167  1.00 25.92  ? 20  ALA D N   1 
ATOM   7005  C  CA  . ALA D 1 20  ? 39.558  5.911   21.923  1.00 23.30  ? 20  ALA D CA  1 
ATOM   7006  C  C   . ALA D 1 20  ? 40.675  5.214   21.165  1.00 22.43  ? 20  ALA D C   1 
ATOM   7007  O  O   . ALA D 1 20  ? 40.395  4.240   20.445  1.00 19.32  ? 20  ALA D O   1 
ATOM   7008  C  CB  . ALA D 1 20  ? 39.431  5.270   23.290  1.00 24.05  ? 20  ALA D CB  1 
ATOM   7009  N  N   . ALA D 1 21  ? 41.906  5.690   21.397  1.00 22.88  ? 21  ALA D N   1 
ATOM   7010  C  CA  . ALA D 1 21  ? 43.060  5.086   20.764  1.00 23.77  ? 21  ALA D CA  1 
ATOM   7011  C  C   . ALA D 1 21  ? 44.283  5.303   21.625  1.00 20.10  ? 21  ALA D C   1 
ATOM   7012  O  O   . ALA D 1 21  ? 44.415  6.349   22.281  1.00 18.35  ? 21  ALA D O   1 
ATOM   7013  C  CB  . ALA D 1 21  ? 43.250  5.780   19.402  1.00 26.24  ? 21  ALA D CB  1 
ATOM   7014  N  N   . ILE D 1 22  ? 45.225  4.378   21.435  1.00 20.64  ? 22  ILE D N   1 
ATOM   7015  C  CA  . ILE D 1 22  ? 46.589  4.573   21.909  1.00 23.67  ? 22  ILE D CA  1 
ATOM   7016  C  C   . ILE D 1 22  ? 47.531  4.359   20.721  1.00 23.69  ? 22  ILE D C   1 
ATOM   7017  O  O   . ILE D 1 22  ? 47.423  3.365   19.962  1.00 20.91  ? 22  ILE D O   1 
ATOM   7018  C  CB  . ILE D 1 22  ? 46.947  3.610   23.055  1.00 26.30  ? 22  ILE D CB  1 
ATOM   7019  C  CG1 . ILE D 1 22  ? 46.266  4.014   24.323  1.00 26.63  ? 22  ILE D CG1 1 
ATOM   7020  C  CG2 . ILE D 1 22  ? 48.455  3.566   23.254  1.00 27.92  ? 22  ILE D CG2 1 
ATOM   7021  C  CD1 . ILE D 1 22  ? 46.564  3.063   25.477  1.00 28.17  ? 22  ILE D CD1 1 
ATOM   7022  N  N   . PHE D 1 23  ? 48.410  5.352   20.560  1.00 19.75  ? 23  PHE D N   1 
ATOM   7023  C  CA  . PHE D 1 23  ? 49.465  5.260   19.578  1.00 20.15  ? 23  PHE D CA  1 
ATOM   7024  C  C   . PHE D 1 23  ? 50.770  5.042   20.333  1.00 20.33  ? 23  PHE D C   1 
ATOM   7025  O  O   . PHE D 1 23  ? 51.151  5.903   21.145  1.00 21.16  ? 23  PHE D O   1 
ATOM   7026  C  CB  . PHE D 1 23  ? 49.550  6.574   18.796  1.00 18.14  ? 23  PHE D CB  1 
ATOM   7027  C  CG  . PHE D 1 23  ? 48.293  6.942   18.071  1.00 19.82  ? 23  PHE D CG  1 
ATOM   7028  C  CD1 . PHE D 1 23  ? 48.052  6.474   16.780  1.00 21.85  ? 23  PHE D CD1 1 
ATOM   7029  C  CD2 . PHE D 1 23  ? 47.358  7.757   18.696  1.00 22.10  ? 23  PHE D CD2 1 
ATOM   7030  C  CE1 . PHE D 1 23  ? 46.864  6.787   16.128  1.00 21.77  ? 23  PHE D CE1 1 
ATOM   7031  C  CE2 . PHE D 1 23  ? 46.178  8.078   18.052  1.00 23.20  ? 23  PHE D CE2 1 
ATOM   7032  C  CZ  . PHE D 1 23  ? 45.947  7.605   16.764  1.00 20.83  ? 23  PHE D CZ  1 
ATOM   7033  N  N   . LEU D 1 24  ? 51.460  3.957   19.998  1.00 19.64  ? 24  LEU D N   1 
ATOM   7034  C  CA  . LEU D 1 24  ? 52.745  3.666   20.591  1.00 24.78  ? 24  LEU D CA  1 
ATOM   7035  C  C   . LEU D 1 24  ? 53.809  3.530   19.501  1.00 24.89  ? 24  LEU D C   1 
ATOM   7036  O  O   . LEU D 1 24  ? 53.657  2.712   18.577  1.00 22.41  ? 24  LEU D O   1 
ATOM   7037  C  CB  . LEU D 1 24  ? 52.474  2.330   21.253  1.00 30.43  ? 24  LEU D CB  1 
ATOM   7038  C  CG  . LEU D 1 24  ? 53.295  2.018   22.487  1.00 38.44  ? 24  LEU D CG  1 
ATOM   7039  C  CD1 . LEU D 1 24  ? 53.132  3.150   23.454  1.00 42.22  ? 24  LEU D CD1 1 
ATOM   7040  C  CD2 . LEU D 1 24  ? 52.707  0.692   23.000  1.00 44.90  ? 24  LEU D CD2 1 
ATOM   7041  N  N   . VAL D 1 25  ? 54.864  4.355   19.618  1.00 23.52  ? 25  VAL D N   1 
ATOM   7042  C  CA  . VAL D 1 25  ? 55.988  4.300   18.703  1.00 23.52  ? 25  VAL D CA  1 
ATOM   7043  C  C   . VAL D 1 25  ? 57.255  3.992   19.481  1.00 23.00  ? 25  VAL D C   1 
ATOM   7044  O  O   . VAL D 1 25  ? 57.537  4.671   20.461  1.00 21.41  ? 25  VAL D O   1 
ATOM   7045  C  CB  . VAL D 1 25  ? 56.180  5.611   17.945  1.00 23.90  ? 25  VAL D CB  1 
ATOM   7046  C  CG1 . VAL D 1 25  ? 57.393  5.514   17.039  1.00 26.08  ? 25  VAL D CG1 1 
ATOM   7047  C  CG2 . VAL D 1 25  ? 54.983  5.895   17.070  1.00 23.49  ? 25  VAL D CG2 1 
ATOM   7048  N  N   . VAL D 1 26  ? 57.962  2.943   19.056  1.00 21.55  ? 26  VAL D N   1 
ATOM   7049  C  CA  . VAL D 1 26  ? 59.159  2.517   19.746  1.00 23.27  ? 26  VAL D CA  1 
ATOM   7050  C  C   . VAL D 1 26  ? 60.299  2.286   18.755  1.00 22.68  ? 26  VAL D C   1 
ATOM   7051  O  O   . VAL D 1 26  ? 60.080  1.999   17.570  1.00 23.79  ? 26  VAL D O   1 
ATOM   7052  C  CB  . VAL D 1 26  ? 58.903  1.241   20.584  1.00 22.31  ? 26  VAL D CB  1 
ATOM   7053  C  CG1 . VAL D 1 26  ? 57.737  1.466   21.535  1.00 22.97  ? 26  VAL D CG1 1 
ATOM   7054  C  CG2 . VAL D 1 26  ? 58.760  -0.041  19.745  1.00 21.87  ? 26  VAL D CG2 1 
ATOM   7055  N  N   . THR D 1 27  ? 61.518  2.335   19.310  1.00 24.56  ? 27  THR D N   1 
ATOM   7056  C  CA  . THR D 1 27  ? 62.726  1.872   18.632  1.00 29.01  ? 27  THR D CA  1 
ATOM   7057  C  C   . THR D 1 27  ? 63.170  0.559   19.265  1.00 26.11  ? 27  THR D C   1 
ATOM   7058  O  O   . THR D 1 27  ? 62.979  0.359   20.454  1.00 23.28  ? 27  THR D O   1 
ATOM   7059  C  CB  . THR D 1 27  ? 63.860  2.907   18.629  1.00 24.28  ? 27  THR D CB  1 
ATOM   7060  O  OG1 . THR D 1 27  ? 64.086  3.423   19.944  1.00 24.99  ? 27  THR D OG1 1 
ATOM   7061  C  CG2 . THR D 1 27  ? 63.506  4.047   17.718  1.00 25.00  ? 27  THR D CG2 1 
ATOM   7062  N  N   . ILE D 1 28  ? 63.720  -0.291  18.396  1.00 25.19  ? 28  ILE D N   1 
ATOM   7063  C  CA  . ILE D 1 28  ? 64.268  -1.569  18.764  1.00 25.73  ? 28  ILE D CA  1 
ATOM   7064  C  C   . ILE D 1 28  ? 65.737  -1.404  19.225  1.00 32.85  ? 28  ILE D C   1 
ATOM   7065  O  O   . ILE D 1 28  ? 66.580  -0.940  18.479  1.00 31.94  ? 28  ILE D O   1 
ATOM   7066  C  CB  . ILE D 1 28  ? 64.134  -2.560  17.610  1.00 22.95  ? 28  ILE D CB  1 
ATOM   7067  C  CG1 . ILE D 1 28  ? 62.722  -2.675  17.087  1.00 25.65  ? 28  ILE D CG1 1 
ATOM   7068  C  CG2 . ILE D 1 28  ? 64.657  -3.915  18.084  1.00 25.32  ? 28  ILE D CG2 1 
ATOM   7069  C  CD1 . ILE D 1 28  ? 62.577  -3.524  15.828  1.00 27.00  ? 28  ILE D CD1 1 
ATOM   7070  N  N   . ASP D 1 29  ? 66.052  -1.812  20.457  1.00 32.47  ? 29  ASP D N   1 
ATOM   7071  C  CA  . ASP D 1 29  ? 67.390  -1.737  21.008  1.00 33.44  ? 29  ASP D CA  1 
ATOM   7072  C  C   . ASP D 1 29  ? 68.232  -2.841  20.353  1.00 36.87  ? 29  ASP D C   1 
ATOM   7073  O  O   . ASP D 1 29  ? 67.681  -3.801  19.767  1.00 29.59  ? 29  ASP D O   1 
ATOM   7074  C  CB  . ASP D 1 29  ? 67.341  -1.856  22.521  1.00 35.64  ? 29  ASP D CB  1 
ATOM   7075  C  CG  . ASP D 1 29  ? 66.591  -0.772  23.305  1.00 41.01  ? 29  ASP D CG  1 
ATOM   7076  O  OD1 . ASP D 1 29  ? 66.109  0.191   22.659  1.00 33.87  ? 29  ASP D OD1 1 
ATOM   7077  O  OD2 . ASP D 1 29  ? 66.504  -0.863  24.579  1.00 43.80  ? 29  ASP D OD2 1 
ATOM   7078  N  N   . SER D 1 30  ? 69.581  -2.675  20.406  1.00 37.99  ? 30  SER D N   1 
ATOM   7079  C  CA  . SER D 1 30  ? 70.461  -3.734  19.896  1.00 40.49  ? 30  SER D CA  1 
ATOM   7080  C  C   . SER D 1 30  ? 70.222  -4.948  20.756  1.00 32.21  ? 30  SER D C   1 
ATOM   7081  O  O   . SER D 1 30  ? 70.197  -4.823  21.970  1.00 31.57  ? 30  SER D O   1 
ATOM   7082  C  CB  . SER D 1 30  ? 71.947  -3.494  19.967  1.00 44.61  ? 30  SER D CB  1 
ATOM   7083  O  OG  . SER D 1 30  ? 72.235  -2.280  19.311  1.00 56.90  ? 30  SER D OG  1 
ATOM   7084  N  N   . GLY D 1 31  ? 70.090  -6.106  20.119  1.00 31.12  ? 31  GLY D N   1 
ATOM   7085  C  CA  . GLY D 1 31  ? 69.822  -7.322  20.855  1.00 33.29  ? 31  GLY D CA  1 
ATOM   7086  C  C   . GLY D 1 31  ? 68.323  -7.613  20.915  1.00 35.94  ? 31  GLY D C   1 
ATOM   7087  O  O   . GLY D 1 31  ? 67.942  -8.731  21.174  1.00 34.86  ? 31  GLY D O   1 
ATOM   7088  N  N   . GLY D 1 32  ? 67.483  -6.650  20.542  1.00 36.77  ? 32  GLY D N   1 
ATOM   7089  C  CA  . GLY D 1 32  ? 66.060  -6.751  20.778  1.00 38.41  ? 32  GLY D CA  1 
ATOM   7090  C  C   . GLY D 1 32  ? 65.315  -7.513  19.688  1.00 35.43  ? 32  GLY D C   1 
ATOM   7091  O  O   . GLY D 1 32  ? 64.148  -7.860  19.861  1.00 36.98  ? 32  GLY D O   1 
ATOM   7092  N  N   . GLU D 1 33  ? 65.996  -7.808  18.595  1.00 31.31  ? 33  GLU D N   1 
ATOM   7093  C  CA  . GLU D 1 33  ? 65.369  -8.328  17.390  1.00 32.84  ? 33  GLU D CA  1 
ATOM   7094  C  C   . GLU D 1 33  ? 64.512  -9.570  17.657  1.00 31.04  ? 33  GLU D C   1 
ATOM   7095  O  O   . GLU D 1 33  ? 63.421  -9.683  17.123  1.00 31.77  ? 33  GLU D O   1 
ATOM   7096  C  CB  . GLU D 1 33  ? 66.409  -8.597  16.273  1.00 32.34  ? 33  GLU D CB  1 
ATOM   7097  C  CG  . GLU D 1 33  ? 67.150  -7.374  15.719  1.00 34.92  ? 33  GLU D CG  1 
ATOM   7098  C  CD  . GLU D 1 33  ? 68.265  -6.729  16.570  1.00 41.03  ? 33  GLU D CD  1 
ATOM   7099  O  OE1 . GLU D 1 33  ? 68.678  -7.372  17.601  1.00 35.81  ? 33  GLU D OE1 1 
ATOM   7100  O  OE2 . GLU D 1 33  ? 68.720  -5.586  16.264  1.00 36.40  ? 33  GLU D OE2 1 
ATOM   7101  N  N   . ASP D 1 34  ? 65.023  -10.549 18.387  1.00 32.61  ? 34  ASP D N   1 
ATOM   7102  C  CA  . ASP D 1 34  ? 64.318  -11.810 18.565  1.00 35.95  ? 34  ASP D CA  1 
ATOM   7103  C  C   . ASP D 1 34  ? 63.096  -11.637 19.470  1.00 31.05  ? 34  ASP D C   1 
ATOM   7104  O  O   . ASP D 1 34  ? 62.040  -12.231 19.257  1.00 28.50  ? 34  ASP D O   1 
ATOM   7105  C  CB  . ASP D 1 34  ? 65.241  -12.864 19.163  1.00 45.78  ? 34  ASP D CB  1 
ATOM   7106  C  CG  . ASP D 1 34  ? 66.225  -13.455 18.157  1.00 49.99  ? 34  ASP D CG  1 
ATOM   7107  O  OD1 . ASP D 1 34  ? 65.728  -13.693 17.020  1.00 58.73  ? 34  ASP D OD1 1 
ATOM   7108  O  OD2 . ASP D 1 34  ? 67.431  -13.685 18.521  1.00 37.78  ? 34  ASP D OD2 1 
ATOM   7109  N  N   . THR D 1 35  ? 63.233  -10.828 20.495  1.00 26.22  ? 35  THR D N   1 
ATOM   7110  C  CA  . THR D 1 35  ? 62.076  -10.543 21.327  1.00 30.97  ? 35  THR D CA  1 
ATOM   7111  C  C   . THR D 1 35  ? 60.949  -9.970  20.475  1.00 27.59  ? 35  THR D C   1 
ATOM   7112  O  O   . THR D 1 35  ? 59.811  -10.382 20.603  1.00 22.92  ? 35  THR D O   1 
ATOM   7113  C  CB  . THR D 1 35  ? 62.459  -9.545  22.414  1.00 29.82  ? 35  THR D CB  1 
ATOM   7114  O  OG1 . THR D 1 35  ? 63.240  -10.392 23.249  1.00 30.68  ? 35  THR D OG1 1 
ATOM   7115  C  CG2 . THR D 1 35  ? 61.262  -9.078  23.212  1.00 32.05  ? 35  THR D CG2 1 
ATOM   7116  N  N   . VAL D 1 36  ? 61.316  -9.016  19.613  1.00 26.93  ? 36  VAL D N   1 
ATOM   7117  C  CA  . VAL D 1 36  ? 60.353  -8.351  18.763  1.00 27.63  ? 36  VAL D CA  1 
ATOM   7118  C  C   . VAL D 1 36  ? 59.684  -9.367  17.851  1.00 29.03  ? 36  VAL D C   1 
ATOM   7119  O  O   . VAL D 1 36  ? 58.465  -9.398  17.765  1.00 32.17  ? 36  VAL D O   1 
ATOM   7120  C  CB  . VAL D 1 36  ? 60.966  -7.179  17.985  1.00 29.01  ? 36  VAL D CB  1 
ATOM   7121  C  CG1 . VAL D 1 36  ? 60.050  -6.660  16.888  1.00 28.03  ? 36  VAL D CG1 1 
ATOM   7122  C  CG2 . VAL D 1 36  ? 61.389  -6.069  18.918  1.00 26.28  ? 36  VAL D CG2 1 
ATOM   7123  N  N   . ARG D 1 37  ? 60.464  -10.216 17.198  1.00 32.57  ? 37  ARG D N   1 
ATOM   7124  C  CA  . ARG D 1 37  ? 59.893  -11.193 16.292  1.00 32.41  ? 37  ARG D CA  1 
ATOM   7125  C  C   . ARG D 1 37  ? 58.904  -12.098 16.993  1.00 29.56  ? 37  ARG D C   1 
ATOM   7126  O  O   . ARG D 1 37  ? 57.903  -12.456 16.388  1.00 35.76  ? 37  ARG D O   1 
ATOM   7127  C  CB  . ARG D 1 37  ? 60.996  -12.046 15.678  1.00 38.74  ? 37  ARG D CB  1 
ATOM   7128  C  CG  . ARG D 1 37  ? 61.733  -11.275 14.590  1.00 47.08  ? 37  ARG D CG  1 
ATOM   7129  C  CD  . ARG D 1 37  ? 63.292  -11.567 14.420  1.00 49.38  ? 37  ARG D CD  1 
ATOM   7130  N  NE  . ARG D 1 37  ? 63.484  -12.756 13.613  1.00 44.19  ? 37  ARG D NE  1 
ATOM   7131  C  CZ  . ARG D 1 37  ? 62.705  -13.033 12.585  1.00 48.98  ? 37  ARG D CZ  1 
ATOM   7132  N  NH1 . ARG D 1 37  ? 62.177  -12.102 11.816  1.00 76.51  ? 37  ARG D NH1 1 
ATOM   7133  N  NH2 . ARG D 1 37  ? 62.534  -14.270 12.218  1.00 53.76  ? 37  ARG D NH2 1 
ATOM   7134  N  N   . ASP D 1 38  ? 59.207  -12.540 18.211  1.00 34.30  ? 38  ASP D N   1 
ATOM   7135  C  CA  . ASP D 1 38  ? 58.263  -13.399 18.939  1.00 45.64  ? 38  ASP D CA  1 
ATOM   7136  C  C   . ASP D 1 38  ? 56.929  -12.692 19.200  1.00 37.89  ? 38  ASP D C   1 
ATOM   7137  O  O   . ASP D 1 38  ? 55.864  -13.279 19.046  1.00 36.30  ? 38  ASP D O   1 
ATOM   7138  C  CB  . ASP D 1 38  ? 58.688  -13.762 20.361  1.00 61.77  ? 38  ASP D CB  1 
ATOM   7139  C  CG  . ASP D 1 38  ? 59.555  -14.998 20.488  1.00 68.66  ? 38  ASP D CG  1 
ATOM   7140  O  OD1 . ASP D 1 38  ? 59.625  -15.744 19.489  1.00 74.46  ? 38  ASP D OD1 1 
ATOM   7141  O  OD2 . ASP D 1 38  ? 60.163  -15.190 21.575  1.00 70.37  ? 38  ASP D OD2 1 
ATOM   7142  N  N   . LEU D 1 39  ? 57.017  -11.440 19.624  1.00 29.29  ? 39  LEU D N   1 
ATOM   7143  C  CA  . LEU D 1 39  ? 55.846  -10.658 19.872  1.00 28.03  ? 39  LEU D CA  1 
ATOM   7144  C  C   . LEU D 1 39  ? 55.041  -10.472 18.587  1.00 27.11  ? 39  LEU D C   1 
ATOM   7145  O  O   . LEU D 1 39  ? 53.835  -10.596 18.616  1.00 32.75  ? 39  LEU D O   1 
ATOM   7146  C  CB  . LEU D 1 39  ? 56.124  -9.305  20.515  1.00 32.62  ? 39  LEU D CB  1 
ATOM   7147  C  CG  . LEU D 1 39  ? 54.816  -8.518  20.445  1.00 36.25  ? 39  LEU D CG  1 
ATOM   7148  C  CD1 . LEU D 1 39  ? 54.102  -8.639  21.736  1.00 35.89  ? 39  LEU D CD1 1 
ATOM   7149  C  CD2 . LEU D 1 39  ? 54.961  -7.167  19.946  1.00 36.33  ? 39  LEU D CD2 1 
ATOM   7150  N  N   . LEU D 1 40  ? 55.654  -10.172 17.452  1.00 28.75  ? 40  LEU D N   1 
ATOM   7151  C  CA  . LEU D 1 40  ? 54.896  -9.965  16.231  1.00 28.55  ? 40  LEU D CA  1 
ATOM   7152  C  C   . LEU D 1 40  ? 54.036  -11.178 15.936  1.00 28.63  ? 40  LEU D C   1 
ATOM   7153  O  O   . LEU D 1 40  ? 52.953  -11.057 15.411  1.00 31.38  ? 40  LEU D O   1 
ATOM   7154  C  CB  . LEU D 1 40  ? 55.822  -9.619  15.060  1.00 27.99  ? 40  LEU D CB  1 
ATOM   7155  C  CG  . LEU D 1 40  ? 56.488  -8.233  15.146  1.00 30.15  ? 40  LEU D CG  1 
ATOM   7156  C  CD1 . LEU D 1 40  ? 57.380  -7.880  14.006  1.00 35.29  ? 40  LEU D CD1 1 
ATOM   7157  C  CD2 . LEU D 1 40  ? 55.502  -7.132  15.195  1.00 31.02  ? 40  LEU D CD2 1 
ATOM   7158  N  N   . SER D 1 41  ? 54.543  -12.354 16.200  1.00 30.72  ? 41  SER D N   1 
ATOM   7159  C  CA  . SER D 1 41  ? 53.830  -13.553 15.804  1.00 36.75  ? 41  SER D CA  1 
ATOM   7160  C  C   . SER D 1 41  ? 52.693  -13.834 16.801  1.00 34.59  ? 41  SER D C   1 
ATOM   7161  O  O   . SER D 1 41  ? 51.864  -14.705 16.590  1.00 32.23  ? 41  SER D O   1 
ATOM   7162  C  CB  . SER D 1 41  ? 54.799  -14.736 15.722  1.00 42.43  ? 41  SER D CB  1 
ATOM   7163  O  OG  . SER D 1 41  ? 55.174  -15.121 17.060  1.00 47.49  ? 41  SER D OG  1 
ATOM   7164  N  N   . ASP D 1 42  ? 52.639  -13.126 17.920  1.00 31.74  ? 42  ASP D N   1 
ATOM   7165  C  CA  . ASP D 1 42  ? 51.597  -13.361 18.900  1.00 31.88  ? 42  ASP D CA  1 
ATOM   7166  C  C   . ASP D 1 42  ? 50.621  -12.196 19.035  1.00 31.95  ? 42  ASP D C   1 
ATOM   7167  O  O   . ASP D 1 42  ? 49.709  -12.246 19.846  1.00 31.70  ? 42  ASP D O   1 
ATOM   7168  C  CB  . ASP D 1 42  ? 52.217  -13.556 20.272  1.00 36.06  ? 42  ASP D CB  1 
ATOM   7169  C  CG  . ASP D 1 42  ? 52.727  -14.971 20.577  1.00 38.58  ? 42  ASP D CG  1 
ATOM   7170  O  OD1 . ASP D 1 42  ? 52.390  -15.985 19.878  1.00 47.07  ? 42  ASP D OD1 1 
ATOM   7171  O  OD2 . ASP D 1 42  ? 53.533  -15.055 21.491  1.00 41.00  ? 42  ASP D OD2 1 
ATOM   7172  N  N   . VAL D 1 43  ? 50.803  -11.102 18.292  1.00 31.67  ? 43  VAL D N   1 
ATOM   7173  C  CA  . VAL D 1 43  ? 50.077  -9.873  18.615  1.00 29.77  ? 43  VAL D CA  1 
ATOM   7174  C  C   . VAL D 1 43  ? 48.610  -10.047 18.280  1.00 24.52  ? 43  VAL D C   1 
ATOM   7175  O  O   . VAL D 1 43  ? 47.775  -9.604  19.044  1.00 23.51  ? 43  VAL D O   1 
ATOM   7176  C  CB  . VAL D 1 43  ? 50.670  -8.621  17.971  1.00 29.77  ? 43  VAL D CB  1 
ATOM   7177  C  CG1 . VAL D 1 43  ? 50.443  -8.708  16.521  1.00 30.72  ? 43  VAL D CG1 1 
ATOM   7178  C  CG2 . VAL D 1 43  ? 50.052  -7.367  18.485  1.00 30.22  ? 43  VAL D CG2 1 
ATOM   7179  N  N   . ALA D 1 44  ? 48.279  -10.814 17.247  1.00 26.75  ? 44  ALA D N   1 
ATOM   7180  C  CA  . ALA D 1 44  ? 46.873  -11.113 16.963  1.00 28.67  ? 44  ALA D CA  1 
ATOM   7181  C  C   . ALA D 1 44  ? 46.226  -11.875 18.106  1.00 29.58  ? 44  ALA D C   1 
ATOM   7182  O  O   . ALA D 1 44  ? 45.053  -11.651 18.403  1.00 36.60  ? 44  ALA D O   1 
ATOM   7183  C  CB  . ALA D 1 44  ? 46.728  -11.945 15.708  1.00 28.21  ? 44  ALA D CB  1 
ATOM   7184  N  N   . SER D 1 45  ? 46.971  -12.783 18.752  1.00 27.26  ? 45  SER D N   1 
ATOM   7185  C  CA  . SER D 1 45  ? 46.317  -13.575 19.762  1.00 27.89  ? 45  SER D CA  1 
ATOM   7186  C  C   . SER D 1 45  ? 46.167  -12.770 21.050  1.00 25.52  ? 45  SER D C   1 
ATOM   7187  O  O   . SER D 1 45  ? 45.170  -12.947 21.742  1.00 28.71  ? 45  SER D O   1 
ATOM   7188  C  CB  . SER D 1 45  ? 46.907  -14.965 19.865  1.00 29.73  ? 45  SER D CB  1 
ATOM   7189  O  OG  . SER D 1 45  ? 48.021  -14.938 20.695  1.00 40.08  ? 45  SER D OG  1 
ATOM   7190  N  N   . LEU D 1 46  ? 47.055  -11.807 21.282  1.00 20.63  ? 46  LEU D N   1 
ATOM   7191  C  CA  . LEU D 1 46  ? 46.874  -10.901 22.386  1.00 22.45  ? 46  LEU D CA  1 
ATOM   7192  C  C   . LEU D 1 46  ? 45.653  -10.009 22.155  1.00 25.84  ? 46  LEU D C   1 
ATOM   7193  O  O   . LEU D 1 46  ? 44.888  -9.744  23.094  1.00 28.03  ? 46  LEU D O   1 
ATOM   7194  C  CB  . LEU D 1 46  ? 48.132  -10.071 22.620  1.00 26.47  ? 46  LEU D CB  1 
ATOM   7195  C  CG  . LEU D 1 46  ? 49.344  -10.867 23.079  1.00 31.70  ? 46  LEU D CG  1 
ATOM   7196  C  CD1 . LEU D 1 46  ? 50.573  -9.960  23.212  1.00 35.14  ? 46  LEU D CD1 1 
ATOM   7197  C  CD2 . LEU D 1 46  ? 49.065  -11.533 24.413  1.00 28.46  ? 46  LEU D CD2 1 
ATOM   7198  N  N   . GLU D 1 47  ? 45.503  -9.520  20.919  1.00 27.33  ? 47  GLU D N   1 
ATOM   7199  C  CA  . GLU D 1 47  ? 44.354  -8.704  20.563  1.00 28.59  ? 47  GLU D CA  1 
ATOM   7200  C  C   . GLU D 1 47  ? 43.052  -9.468  20.908  1.00 28.37  ? 47  GLU D C   1 
ATOM   7201  O  O   . GLU D 1 47  ? 42.173  -8.916  21.566  1.00 27.88  ? 47  GLU D O   1 
ATOM   7202  C  CB  . GLU D 1 47  ? 44.520  -8.319  19.105  1.00 26.68  ? 47  GLU D CB  1 
ATOM   7203  C  CG  . GLU D 1 47  ? 43.314  -7.566  18.589  1.00 28.49  ? 47  GLU D CG  1 
ATOM   7204  C  CD  . GLU D 1 47  ? 43.247  -7.486  17.088  1.00 35.52  ? 47  GLU D CD  1 
ATOM   7205  O  OE1 . GLU D 1 47  ? 43.811  -6.614  16.466  1.00 37.85  ? 47  GLU D OE1 1 
ATOM   7206  O  OE2 . GLU D 1 47  ? 42.619  -8.339  16.543  1.00 41.48  ? 47  GLU D OE2 1 
ATOM   7207  N  N   . ARG D 1 48  ? 42.942  -10.754 20.553  1.00 28.86  ? 48  ARG D N   1 
ATOM   7208  C  CA  . ARG D 1 48  ? 41.760  -11.535 20.938  1.00 31.53  ? 48  ARG D CA  1 
ATOM   7209  C  C   . ARG D 1 48  ? 41.639  -11.766 22.440  1.00 26.91  ? 48  ARG D C   1 
ATOM   7210  O  O   . ARG D 1 48  ? 40.558  -11.665 22.987  1.00 34.31  ? 48  ARG D O   1 
ATOM   7211  C  CB  . ARG D 1 48  ? 41.667  -12.907 20.290  1.00 32.99  ? 48  ARG D CB  1 
ATOM   7212  C  CG  . ARG D 1 48  ? 41.475  -12.725 18.805  1.00 36.82  ? 48  ARG D CG  1 
ATOM   7213  C  CD  . ARG D 1 48  ? 41.134  -14.041 18.221  1.00 41.34  ? 48  ARG D CD  1 
ATOM   7214  N  NE  . ARG D 1 48  ? 42.302  -14.926 18.270  1.00 51.23  ? 48  ARG D NE  1 
ATOM   7215  C  CZ  . ARG D 1 48  ? 43.357  -14.950 17.433  1.00 50.48  ? 48  ARG D CZ  1 
ATOM   7216  N  NH1 . ARG D 1 48  ? 43.517  -14.092 16.462  1.00 47.37  ? 48  ARG D NH1 1 
ATOM   7217  N  NH2 . ARG D 1 48  ? 44.313  -15.843 17.564  1.00 63.40  ? 48  ARG D NH2 1 
ATOM   7218  N  N   . ALA D 1 49  ? 42.725  -12.084 23.122  1.00 25.78  ? 49  ALA D N   1 
ATOM   7219  C  CA  . ALA D 1 49  ? 42.627  -12.296 24.555  1.00 27.33  ? 49  ALA D CA  1 
ATOM   7220  C  C   . ALA D 1 49  ? 42.046  -11.083 25.302  1.00 28.66  ? 49  ALA D C   1 
ATOM   7221  O  O   . ALA D 1 49  ? 41.168  -11.205 26.178  1.00 29.80  ? 49  ALA D O   1 
ATOM   7222  C  CB  . ALA D 1 49  ? 44.000  -12.630 25.088  1.00 29.23  ? 49  ALA D CB  1 
ATOM   7223  N  N   . VAL D 1 50  ? 42.586  -9.899  25.008  1.00 26.18  ? 50  VAL D N   1 
ATOM   7224  C  CA  . VAL D 1 50  ? 42.112  -8.698  25.681  1.00 28.07  ? 50  VAL D CA  1 
ATOM   7225  C  C   . VAL D 1 50  ? 40.726  -8.325  25.186  1.00 27.50  ? 50  VAL D C   1 
ATOM   7226  O  O   . VAL D 1 50  ? 39.951  -7.821  25.956  1.00 33.46  ? 50  VAL D O   1 
ATOM   7227  C  CB  . VAL D 1 50  ? 43.010  -7.464  25.560  1.00 28.74  ? 50  VAL D CB  1 
ATOM   7228  C  CG1 . VAL D 1 50  ? 42.387  -6.262  26.245  1.00 27.87  ? 50  VAL D CG1 1 
ATOM   7229  C  CG2 . VAL D 1 50  ? 44.382  -7.735  26.122  1.00 27.41  ? 50  VAL D CG2 1 
ATOM   7230  N  N   . GLY D 1 51  ? 40.424  -8.561  23.919  1.00 25.51  ? 51  GLY D N   1 
ATOM   7231  C  CA  . GLY D 1 51  ? 39.214  -8.026  23.339  1.00 29.64  ? 51  GLY D CA  1 
ATOM   7232  C  C   . GLY D 1 51  ? 37.980  -8.917  23.460  1.00 32.31  ? 51  GLY D C   1 
ATOM   7233  O  O   . GLY D 1 51  ? 36.859  -8.392  23.565  1.00 30.86  ? 51  GLY D O   1 
ATOM   7234  N  N   . PHE D 1 52  ? 38.177  -10.244 23.433  1.00 31.79  ? 52  PHE D N   1 
ATOM   7235  C  CA  . PHE D 1 52  ? 37.059  -11.160 23.262  1.00 33.35  ? 52  PHE D CA  1 
ATOM   7236  C  C   . PHE D 1 52  ? 36.020  -10.964 24.362  1.00 31.91  ? 52  PHE D C   1 
ATOM   7237  O  O   . PHE D 1 52  ? 34.837  -10.867 24.076  1.00 36.63  ? 52  PHE D O   1 
ATOM   7238  C  CB  . PHE D 1 52  ? 37.470  -12.624 23.186  1.00 32.33  ? 52  PHE D CB  1 
ATOM   7239  C  CG  . PHE D 1 52  ? 36.239  -13.470 22.970  1.00 32.91  ? 52  PHE D CG  1 
ATOM   7240  C  CD1 . PHE D 1 52  ? 35.687  -13.589 21.717  1.00 30.19  ? 52  PHE D CD1 1 
ATOM   7241  C  CD2 . PHE D 1 52  ? 35.619  -14.110 24.048  1.00 34.31  ? 52  PHE D CD2 1 
ATOM   7242  C  CE1 . PHE D 1 52  ? 34.571  -14.379 21.520  1.00 34.38  ? 52  PHE D CE1 1 
ATOM   7243  C  CE2 . PHE D 1 52  ? 34.469  -14.885 23.868  1.00 29.93  ? 52  PHE D CE2 1 
ATOM   7244  C  CZ  . PHE D 1 52  ? 33.935  -14.996 22.596  1.00 33.18  ? 52  PHE D CZ  1 
ATOM   7245  N  N   . ARG D 1 53  ? 36.443  -10.821 25.603  1.00 33.04  ? 53  ARG D N   1 
ATOM   7246  C  CA  . ARG D 1 53  ? 35.488  -10.826 26.686  1.00 43.40  ? 53  ARG D CA  1 
ATOM   7247  C  C   . ARG D 1 53  ? 34.664  -9.546  26.747  1.00 52.04  ? 53  ARG D C   1 
ATOM   7248  O  O   . ARG D 1 53  ? 33.739  -9.468  27.567  1.00 50.76  ? 53  ARG D O   1 
ATOM   7249  C  CB  . ARG D 1 53  ? 36.246  -11.040 27.997  1.00 57.70  ? 53  ARG D CB  1 
ATOM   7250  C  CG  . ARG D 1 53  ? 37.309  -10.064 28.500  1.00 57.37  ? 53  ARG D CG  1 
ATOM   7251  C  CD  . ARG D 1 53  ? 37.511  -10.390 30.046  1.00 59.22  ? 53  ARG D CD  1 
ATOM   7252  N  NE  . ARG D 1 53  ? 38.697  -9.755  30.596  1.00 42.33  ? 53  ARG D NE  1 
ATOM   7253  C  CZ  . ARG D 1 53  ? 39.822  -9.998  29.937  1.00 51.06  ? 53  ARG D CZ  1 
ATOM   7254  N  NH1 . ARG D 1 53  ? 39.878  -10.740 28.816  1.00 48.29  ? 53  ARG D NH1 1 
ATOM   7255  N  NH2 . ARG D 1 53  ? 40.940  -9.536  30.445  1.00 60.31  ? 53  ARG D NH2 1 
ATOM   7256  N  N   . ALA D 1 54  ? 35.029  -8.537  25.939  1.00 46.96  ? 54  ALA D N   1 
ATOM   7257  C  CA  . ALA D 1 54  ? 34.250  -7.308  25.879  1.00 48.60  ? 54  ALA D CA  1 
ATOM   7258  C  C   . ALA D 1 54  ? 33.498  -7.164  24.548  1.00 45.21  ? 54  ALA D C   1 
ATOM   7259  O  O   . ALA D 1 54  ? 33.139  -6.072  24.179  1.00 50.86  ? 54  ALA D O   1 
ATOM   7260  C  CB  . ALA D 1 54  ? 35.160  -6.145  26.153  1.00 50.65  ? 54  ALA D CB  1 
ATOM   7261  N  N   . GLN D 1 55  ? 33.232  -8.254  23.814  1.00 54.69  ? 55  GLN D N   1 
ATOM   7262  C  CA  . GLN D 1 55  ? 32.571  -8.196  22.502  1.00 62.92  ? 55  GLN D CA  1 
ATOM   7263  C  C   . GLN D 1 55  ? 31.071  -7.993  22.787  1.00 73.32  ? 55  GLN D C   1 
ATOM   7264  O  O   . GLN D 1 55  ? 30.626  -8.156  23.934  1.00 59.91  ? 55  GLN D O   1 
ATOM   7265  C  CB  . GLN D 1 55  ? 32.950  -9.322  21.495  1.00 64.84  ? 55  GLN D CB  1 
ATOM   7266  C  CG  . GLN D 1 55  ? 34.148  -9.077  20.548  1.00 48.79  ? 55  GLN D CG  1 
ATOM   7267  N  N   . PRO D 1 56  ? 30.289  -7.379  21.844  1.00 91.61  ? 56  PRO D N   1 
ATOM   7268  C  CA  . PRO D 1 56  ? 30.820  -6.753  20.616  1.00 81.06  ? 56  PRO D CA  1 
ATOM   7269  C  C   . PRO D 1 56  ? 30.945  -5.218  20.726  1.00 74.09  ? 56  PRO D C   1 
ATOM   7270  O  O   . PRO D 1 56  ? 31.422  -4.588  19.792  1.00 61.38  ? 56  PRO D O   1 
ATOM   7271  C  CB  . PRO D 1 56  ? 29.762  -7.265  19.585  1.00 61.67  ? 56  PRO D CB  1 
ATOM   7272  C  CG  . PRO D 1 56  ? 28.466  -7.374  20.424  1.00 70.02  ? 56  PRO D CG  1 
ATOM   7273  C  CD  . PRO D 1 56  ? 28.826  -7.156  21.925  1.00 72.20  ? 56  PRO D CD  1 
ATOM   7274  N  N   . ASP D 1 57  ? 30.587  -4.646  21.912  1.00 70.85  ? 57  ASP D N   1 
ATOM   7275  C  CA  . ASP D 1 57  ? 30.677  -3.235  22.266  1.00 59.75  ? 57  ASP D CA  1 
ATOM   7276  C  C   . ASP D 1 57  ? 32.169  -2.773  22.164  1.00 56.13  ? 57  ASP D C   1 
ATOM   7277  O  O   . ASP D 1 57  ? 32.482  -1.635  21.789  1.00 55.26  ? 57  ASP D O   1 
ATOM   7278  C  CB  . ASP D 1 57  ? 29.785  -2.998  23.512  1.00 44.34  ? 57  ASP D CB  1 
ATOM   7279  N  N   . GLY D 1 58  ? 33.154  -3.644  22.436  1.00 49.92  ? 58  GLY D N   1 
ATOM   7280  C  CA  . GLY D 1 58  ? 34.532  -3.208  22.633  1.00 43.26  ? 58  GLY D CA  1 
ATOM   7281  C  C   . GLY D 1 58  ? 35.240  -2.727  21.359  1.00 37.86  ? 58  GLY D C   1 
ATOM   7282  O  O   . GLY D 1 58  ? 35.969  -1.732  21.387  1.00 40.69  ? 58  GLY D O   1 
ATOM   7283  N  N   . ARG D 1 59  ? 35.146  -3.508  20.294  1.00 35.88  ? 59  ARG D N   1 
ATOM   7284  C  CA  . ARG D 1 59  ? 35.763  -3.181  19.012  1.00 41.99  ? 59  ARG D CA  1 
ATOM   7285  C  C   . ARG D 1 59  ? 37.256  -2.894  19.112  1.00 37.75  ? 59  ARG D C   1 
ATOM   7286  O  O   . ARG D 1 59  ? 37.761  -1.970  18.465  1.00 34.58  ? 59  ARG D O   1 
ATOM   7287  C  CB  . ARG D 1 59  ? 34.988  -2.007  18.415  1.00 51.75  ? 59  ARG D CB  1 
ATOM   7288  C  CG  . ARG D 1 59  ? 33.752  -2.617  17.768  1.00 73.36  ? 59  ARG D CG  1 
ATOM   7289  C  CD  . ARG D 1 59  ? 32.921  -1.566  17.090  1.00 88.23  ? 59  ARG D CD  1 
ATOM   7290  N  NE  . ARG D 1 59  ? 32.416  -0.848  18.263  1.00 101.39 ? 59  ARG D NE  1 
ATOM   7291  C  CZ  . ARG D 1 59  ? 31.373  -0.054  18.279  1.00 84.12  ? 59  ARG D CZ  1 
ATOM   7292  N  NH1 . ARG D 1 59  ? 30.876  0.375   17.131  1.00 74.02  ? 59  ARG D NH1 1 
ATOM   7293  N  NH2 . ARG D 1 59  ? 30.903  0.342   19.451  1.00 67.47  ? 59  ARG D NH2 1 
ATOM   7294  N  N   . LEU D 1 60  ? 37.957  -3.690  19.920  1.00 31.11  ? 60  LEU D N   1 
ATOM   7295  C  CA  . LEU D 1 60  ? 39.394  -3.528  20.096  1.00 28.35  ? 60  LEU D CA  1 
ATOM   7296  C  C   . LEU D 1 60  ? 40.151  -4.068  18.889  1.00 26.04  ? 60  LEU D C   1 
ATOM   7297  O  O   . LEU D 1 60  ? 39.924  -5.176  18.470  1.00 27.75  ? 60  LEU D O   1 
ATOM   7298  C  CB  . LEU D 1 60  ? 39.869  -4.206  21.360  1.00 26.09  ? 60  LEU D CB  1 
ATOM   7299  C  CG  . LEU D 1 60  ? 41.390  -4.335  21.520  1.00 27.50  ? 60  LEU D CG  1 
ATOM   7300  C  CD1 . LEU D 1 60  ? 41.941  -2.996  21.870  1.00 29.35  ? 60  LEU D CD1 1 
ATOM   7301  C  CD2 . LEU D 1 60  ? 41.664  -5.338  22.606  1.00 28.88  ? 60  LEU D CD2 1 
ATOM   7302  N  N   . SER D 1 61  ? 41.047  -3.259  18.301  1.00 26.81  ? 61  SER D N   1 
ATOM   7303  C  CA  . SER D 1 61  ? 41.961  -3.746  17.283  1.00 25.20  ? 61  SER D CA  1 
ATOM   7304  C  C   . SER D 1 61  ? 43.320  -3.117  17.511  1.00 24.25  ? 61  SER D C   1 
ATOM   7305  O  O   . SER D 1 61  ? 43.425  -2.071  18.114  1.00 23.29  ? 61  SER D O   1 
ATOM   7306  C  CB  . SER D 1 61  ? 41.512  -3.424  15.930  1.00 26.10  ? 61  SER D CB  1 
ATOM   7307  O  OG  . SER D 1 61  ? 41.356  -2.029  15.778  1.00 30.43  ? 61  SER D OG  1 
ATOM   7308  N  N   . CYS D 1 62  ? 44.336  -3.787  17.006  1.00 30.32  ? 62  CYS D N   1 
ATOM   7309  C  CA  . CYS D 1 62  ? 45.702  -3.301  17.029  1.00 27.70  ? 62  CYS D CA  1 
ATOM   7310  C  C   . CYS D 1 62  ? 46.295  -3.437  15.634  1.00 24.52  ? 62  CYS D C   1 
ATOM   7311  O  O   . CYS D 1 62  ? 46.238  -4.496  15.068  1.00 23.45  ? 62  CYS D O   1 
ATOM   7312  C  CB  . CYS D 1 62  ? 46.522  -4.143  17.968  1.00 26.66  ? 62  CYS D CB  1 
ATOM   7313  S  SG  . CYS D 1 62  ? 48.206  -3.526  17.997  1.00 28.34  ? 62  CYS D SG  1 
ATOM   7314  N  N   . VAL D 1 63  ? 46.768  -2.369  15.035  1.00 20.79  ? 63  VAL D N   1 
ATOM   7315  C  CA  . VAL D 1 63  ? 47.473  -2.503  13.783  1.00 21.83  ? 63  VAL D CA  1 
ATOM   7316  C  C   . VAL D 1 63  ? 48.955  -2.238  14.039  1.00 25.04  ? 63  VAL D C   1 
ATOM   7317  O  O   . VAL D 1 63  ? 49.328  -1.253  14.695  1.00 22.94  ? 63  VAL D O   1 
ATOM   7318  C  CB  . VAL D 1 63  ? 46.902  -1.520  12.750  1.00 26.88  ? 63  VAL D CB  1 
ATOM   7319  C  CG1 . VAL D 1 63  ? 47.710  -1.504  11.471  1.00 32.80  ? 63  VAL D CG1 1 
ATOM   7320  C  CG2 . VAL D 1 63  ? 45.471  -1.862  12.387  1.00 25.36  ? 63  VAL D CG2 1 
ATOM   7321  N  N   . THR D 1 64  ? 49.790  -3.165  13.534  1.00 23.21  ? 64  THR D N   1 
ATOM   7322  C  CA  . THR D 1 64  ? 51.204  -3.160  13.817  1.00 24.11  ? 64  THR D CA  1 
ATOM   7323  C  C   . THR D 1 64  ? 51.934  -2.814  12.538  1.00 22.37  ? 64  THR D C   1 
ATOM   7324  O  O   . THR D 1 64  ? 51.709  -3.421  11.477  1.00 19.24  ? 64  THR D O   1 
ATOM   7325  C  CB  . THR D 1 64  ? 51.642  -4.540  14.301  1.00 31.71  ? 64  THR D CB  1 
ATOM   7326  O  OG1 . THR D 1 64  ? 50.874  -4.847  15.465  1.00 26.62  ? 64  THR D OG1 1 
ATOM   7327  C  CG2 . THR D 1 64  ? 53.128  -4.568  14.614  1.00 32.31  ? 64  THR D CG2 1 
ATOM   7328  N  N   . GLY D 1 65  ? 52.825  -1.808  12.669  1.00 23.85  ? 65  GLY D N   1 
ATOM   7329  C  CA  . GLY D 1 65  ? 53.639  -1.387  11.534  1.00 25.51  ? 65  GLY D CA  1 
ATOM   7330  C  C   . GLY D 1 65  ? 55.140  -1.361  11.835  1.00 22.18  ? 65  GLY D C   1 
ATOM   7331  O  O   . GLY D 1 65  ? 55.582  -1.170  12.989  1.00 22.47  ? 65  GLY D O   1 
ATOM   7332  N  N   . ILE D 1 66  ? 55.906  -1.495  10.746  1.00 21.27  ? 66  ILE D N   1 
ATOM   7333  C  CA  . ILE D 1 66  ? 57.348  -1.663  10.814  1.00 20.85  ? 66  ILE D CA  1 
ATOM   7334  C  C   . ILE D 1 66  ? 58.009  -0.656  9.889   1.00 19.25  ? 66  ILE D C   1 
ATOM   7335  O  O   . ILE D 1 66  ? 57.589  -0.501  8.754   1.00 19.56  ? 66  ILE D O   1 
ATOM   7336  C  CB  . ILE D 1 66  ? 57.671  -3.114  10.438  1.00 23.13  ? 66  ILE D CB  1 
ATOM   7337  C  CG1 . ILE D 1 66  ? 57.002  -4.100  11.399  1.00 24.18  ? 66  ILE D CG1 1 
ATOM   7338  C  CG2 . ILE D 1 66  ? 59.190  -3.297  10.408  1.00 24.66  ? 66  ILE D CG2 1 
ATOM   7339  C  CD1 . ILE D 1 66  ? 56.747  -5.416  10.746  1.00 29.02  ? 66  ILE D CD1 1 
ATOM   7340  N  N   . GLY D 1 67  ? 58.996  0.040   10.386  1.00 18.64  ? 67  GLY D N   1 
ATOM   7341  C  CA  . GLY D 1 67  ? 59.718  0.986   9.554   1.00 23.08  ? 67  GLY D CA  1 
ATOM   7342  C  C   . GLY D 1 67  ? 60.778  0.350   8.630   1.00 28.93  ? 67  GLY D C   1 
ATOM   7343  O  O   . GLY D 1 67  ? 61.145  -0.826  8.718   1.00 26.95  ? 67  GLY D O   1 
ATOM   7344  N  N   . SER D 1 68  ? 61.329  1.211   7.770   1.00 29.69  ? 68  SER D N   1 
ATOM   7345  C  CA  . SER D 1 68  ? 62.320  0.862   6.748   1.00 28.09  ? 68  SER D CA  1 
ATOM   7346  C  C   . SER D 1 68  ? 63.605  0.275   7.335   1.00 25.48  ? 68  SER D C   1 
ATOM   7347  O  O   . SER D 1 68  ? 63.981  -0.832  6.995   1.00 25.46  ? 68  SER D O   1 
ATOM   7348  C  CB  . SER D 1 68  ? 62.631  2.125   5.958   1.00 29.55  ? 68  SER D CB  1 
ATOM   7349  O  OG  . SER D 1 68  ? 63.242  1.744   4.758   1.00 23.16  ? 68  SER D OG  1 
ATOM   7350  N  N   . GLU D 1 69  ? 64.272  1.021   8.227   1.00 25.51  ? 69  GLU D N   1 
ATOM   7351  C  CA  . GLU D 1 69  ? 65.500  0.561   8.865   1.00 27.17  ? 69  GLU D CA  1 
ATOM   7352  C  C   . GLU D 1 69  ? 65.273  -0.717  9.639   1.00 28.57  ? 69  GLU D C   1 
ATOM   7353  O  O   . GLU D 1 69  ? 66.110  -1.613  9.609   1.00 31.72  ? 69  GLU D O   1 
ATOM   7354  C  CB  . GLU D 1 69  ? 66.034  1.632   9.816   1.00 32.92  ? 69  GLU D CB  1 
ATOM   7355  C  CG  . GLU D 1 69  ? 66.419  2.837   8.962   1.00 44.88  ? 69  GLU D CG  1 
ATOM   7356  C  CD  . GLU D 1 69  ? 67.141  4.036   9.500   1.00 53.06  ? 69  GLU D CD  1 
ATOM   7357  O  OE1 . GLU D 1 69  ? 67.106  4.250   10.721  1.00 61.41  ? 69  GLU D OE1 1 
ATOM   7358  O  OE2 . GLU D 1 69  ? 67.717  4.751   8.630   1.00 64.00  ? 69  GLU D OE2 1 
ATOM   7359  N  N   . ALA D 1 70  ? 64.136  -0.778  10.348  1.00 32.23  ? 70  ALA D N   1 
ATOM   7360  C  CA  . ALA D 1 70  ? 63.817  -1.944  11.170  1.00 26.51  ? 70  ALA D CA  1 
ATOM   7361  C  C   . ALA D 1 70  ? 63.500  -3.140  10.292  1.00 22.40  ? 70  ALA D C   1 
ATOM   7362  O  O   . ALA D 1 70  ? 63.816  -4.272  10.623  1.00 24.30  ? 70  ALA D O   1 
ATOM   7363  C  CB  . ALA D 1 70  ? 62.698  -1.633  12.110  1.00 27.59  ? 70  ALA D CB  1 
ATOM   7364  N  N   . TRP D 1 71  ? 62.851  -2.920  9.183   1.00 23.52  ? 71  TRP D N   1 
ATOM   7365  C  CA  . TRP D 1 71  ? 62.547  -4.053  8.316   1.00 28.14  ? 71  TRP D CA  1 
ATOM   7366  C  C   . TRP D 1 71  ? 63.797  -4.858  7.937   1.00 29.63  ? 71  TRP D C   1 
ATOM   7367  O  O   . TRP D 1 71  ? 63.778  -6.076  7.983   1.00 27.42  ? 71  TRP D O   1 
ATOM   7368  C  CB  . TRP D 1 71  ? 61.856  -3.549  7.054   1.00 30.61  ? 71  TRP D CB  1 
ATOM   7369  C  CG  . TRP D 1 71  ? 61.358  -4.684  6.234   1.00 27.78  ? 71  TRP D CG  1 
ATOM   7370  C  CD1 . TRP D 1 71  ? 62.088  -5.448  5.391   1.00 29.34  ? 71  TRP D CD1 1 
ATOM   7371  C  CD2 . TRP D 1 71  ? 60.035  -5.219  6.259   1.00 26.89  ? 71  TRP D CD2 1 
ATOM   7372  N  NE1 . TRP D 1 71  ? 61.289  -6.406  4.849   1.00 27.36  ? 71  TRP D NE1 1 
ATOM   7373  C  CE2 . TRP D 1 71  ? 60.022  -6.288  5.365   1.00 29.39  ? 71  TRP D CE2 1 
ATOM   7374  C  CE3 . TRP D 1 71  ? 58.864  -4.886  6.925   1.00 32.27  ? 71  TRP D CE3 1 
ATOM   7375  C  CZ2 . TRP D 1 71  ? 58.873  -7.041  5.123   1.00 32.10  ? 71  TRP D CZ2 1 
ATOM   7376  C  CZ3 . TRP D 1 71  ? 57.743  -5.656  6.729   1.00 35.08  ? 71  TRP D CZ3 1 
ATOM   7377  C  CH2 . TRP D 1 71  ? 57.752  -6.734  5.842   1.00 33.30  ? 71  TRP D CH2 1 
ATOM   7378  N  N   . ASP D 1 72  ? 64.895  -4.146  7.642   1.00 38.73  ? 72  ASP D N   1 
ATOM   7379  C  CA  . ASP D 1 72  ? 66.195  -4.738  7.280   1.00 38.56  ? 72  ASP D CA  1 
ATOM   7380  C  C   . ASP D 1 72  ? 66.846  -5.483  8.455   1.00 38.42  ? 72  ASP D C   1 
ATOM   7381  O  O   . ASP D 1 72  ? 67.481  -6.514  8.274   1.00 35.76  ? 72  ASP D O   1 
ATOM   7382  C  CB  . ASP D 1 72  ? 67.128  -3.686  6.689   1.00 32.04  ? 72  ASP D CB  1 
ATOM   7383  C  CG  . ASP D 1 72  ? 66.647  -3.118  5.380   1.00 34.74  ? 72  ASP D CG  1 
ATOM   7384  O  OD1 . ASP D 1 72  ? 65.956  -3.885  4.598   1.00 33.78  ? 72  ASP D OD1 1 
ATOM   7385  O  OD2 . ASP D 1 72  ? 67.023  -1.949  5.167   1.00 41.33  ? 72  ASP D OD2 1 
ATOM   7386  N  N   . ARG D 1 73  ? 66.653  -5.007  9.681   1.00 34.03  ? 73  ARG D N   1 
ATOM   7387  C  CA  . ARG D 1 73  ? 67.164  -5.719  10.828  1.00 29.40  ? 73  ARG D CA  1 
ATOM   7388  C  C   . ARG D 1 73  ? 66.355  -6.973  11.122  1.00 30.25  ? 73  ARG D C   1 
ATOM   7389  O  O   . ARG D 1 73  ? 66.888  -7.874  11.755  1.00 38.03  ? 73  ARG D O   1 
ATOM   7390  C  CB  . ARG D 1 73  ? 67.201  -4.861  12.100  1.00 31.63  ? 73  ARG D CB  1 
ATOM   7391  C  CG  . ARG D 1 73  ? 67.968  -3.549  11.946  1.00 31.16  ? 73  ARG D CG  1 
ATOM   7392  C  CD  . ARG D 1 73  ? 67.688  -2.609  13.084  1.00 28.43  ? 73  ARG D CD  1 
ATOM   7393  N  NE  . ARG D 1 73  ? 68.002  -3.204  14.402  1.00 30.70  ? 73  ARG D NE  1 
ATOM   7394  C  CZ  . ARG D 1 73  ? 67.710  -2.505  15.558  1.00 29.16  ? 73  ARG D CZ  1 
ATOM   7395  N  NH1 . ARG D 1 73  ? 67.106  -1.304  15.531  1.00 27.67  ? 73  ARG D NH1 1 
ATOM   7396  N  NH2 . ARG D 1 73  ? 67.983  -3.005  16.746  1.00 30.60  ? 73  ARG D NH2 1 
ATOM   7397  N  N   . LEU D 1 74  ? 65.097  -7.062  10.720  1.00 26.47  ? 74  LEU D N   1 
ATOM   7398  C  CA  . LEU D 1 74  ? 64.270  -8.070  11.310  1.00 25.48  ? 74  LEU D CA  1 
ATOM   7399  C  C   . LEU D 1 74  ? 64.120  -9.189  10.345  1.00 26.72  ? 74  LEU D C   1 
ATOM   7400  O  O   . LEU D 1 74  ? 63.786  -10.267 10.781  1.00 36.14  ? 74  LEU D O   1 
ATOM   7401  C  CB  . LEU D 1 74  ? 62.893  -7.508  11.606  1.00 28.76  ? 74  LEU D CB  1 
ATOM   7402  C  CG  . LEU D 1 74  ? 62.772  -6.579  12.810  1.00 31.66  ? 74  LEU D CG  1 
ATOM   7403  C  CD1 . LEU D 1 74  ? 61.302  -6.142  12.906  1.00 36.46  ? 74  LEU D CD1 1 
ATOM   7404  C  CD2 . LEU D 1 74  ? 63.245  -7.278  14.085  1.00 31.46  ? 74  LEU D CD2 1 
ATOM   7405  N  N   . PHE D 1 75  ? 64.140  -8.880  9.062   1.00 32.19  ? 75  PHE D N   1 
ATOM   7406  C  CA  . PHE D 1 75  ? 63.662  -9.840  8.055   1.00 40.18  ? 75  PHE D CA  1 
ATOM   7407  C  C   . PHE D 1 75  ? 64.667  -9.909  6.914   1.00 47.65  ? 75  PHE D C   1 
ATOM   7408  O  O   . PHE D 1 75  ? 65.340  -8.928  6.540   1.00 45.45  ? 75  PHE D O   1 
ATOM   7409  C  CB  . PHE D 1 75  ? 62.350  -9.465  7.361   1.00 38.89  ? 75  PHE D CB  1 
ATOM   7410  C  CG  . PHE D 1 75  ? 61.242  -9.180  8.356   1.00 42.57  ? 75  PHE D CG  1 
ATOM   7411  C  CD1 . PHE D 1 75  ? 60.860  -10.153 9.241   1.00 42.93  ? 75  PHE D CD1 1 
ATOM   7412  C  CD2 . PHE D 1 75  ? 60.645  -7.931  8.448   1.00 45.15  ? 75  PHE D CD2 1 
ATOM   7413  C  CE1 . PHE D 1 75  ? 59.856  -9.914  10.146  1.00 44.54  ? 75  PHE D CE1 1 
ATOM   7414  C  CE2 . PHE D 1 75  ? 59.674  -7.692  9.393   1.00 50.49  ? 75  PHE D CE2 1 
ATOM   7415  C  CZ  . PHE D 1 75  ? 59.280  -8.679  10.239  1.00 45.78  ? 75  PHE D CZ  1 
ATOM   7416  N  N   . SER D 1 76  ? 64.754  -11.077 6.318   1.00 54.08  ? 76  SER D N   1 
ATOM   7417  C  CA  . SER D 1 76  ? 65.542  -11.094 5.100   1.00 64.51  ? 76  SER D CA  1 
ATOM   7418  C  C   . SER D 1 76  ? 64.594  -11.414 3.958   1.00 59.00  ? 76  SER D C   1 
ATOM   7419  O  O   . SER D 1 76  ? 63.439  -11.806 4.161   1.00 64.82  ? 76  SER D O   1 
ATOM   7420  C  CB  . SER D 1 76  ? 66.740  -12.003 5.209   1.00 61.00  ? 76  SER D CB  1 
ATOM   7421  O  OG  . SER D 1 76  ? 66.456  -13.044 6.142   1.00 63.82  ? 76  SER D OG  1 
ATOM   7422  N  N   . GLY D 1 77  ? 65.063  -11.189 2.752   1.00 52.84  ? 77  GLY D N   1 
ATOM   7423  C  CA  . GLY D 1 77  ? 64.161  -11.481 1.652   1.00 50.57  ? 77  GLY D CA  1 
ATOM   7424  C  C   . GLY D 1 77  ? 63.653  -10.164 1.122   1.00 46.48  ? 77  GLY D C   1 
ATOM   7425  O  O   . GLY D 1 77  ? 64.366  -9.166  1.140   1.00 43.09  ? 77  GLY D O   1 
ATOM   7426  N  N   . ALA D 1 78  ? 62.446  -10.182 0.603   1.00 42.25  ? 78  ALA D N   1 
ATOM   7427  C  CA  . ALA D 1 78  ? 61.935  -9.041  -0.124  1.00 38.92  ? 78  ALA D CA  1 
ATOM   7428  C  C   . ALA D 1 78  ? 61.544  -7.929  0.870   1.00 44.00  ? 78  ALA D C   1 
ATOM   7429  O  O   . ALA D 1 78  ? 61.131  -8.218  2.012   1.00 37.80  ? 78  ALA D O   1 
ATOM   7430  C  CB  . ALA D 1 78  ? 60.777  -9.541  -0.964  1.00 43.22  ? 78  ALA D CB  1 
ATOM   7431  N  N   . ARG D 1 79  ? 61.742  -6.672  0.406   1.00 44.91  ? 79  ARG D N   1 
ATOM   7432  C  CA  . ARG D 1 79  ? 61.147  -5.455  0.940   1.00 42.36  ? 79  ARG D CA  1 
ATOM   7433  C  C   . ARG D 1 79  ? 59.808  -5.086  0.269   1.00 39.53  ? 79  ARG D C   1 
ATOM   7434  O  O   . ARG D 1 79  ? 59.640  -5.211  -0.932  1.00 42.31  ? 79  ARG D O   1 
ATOM   7435  C  CB  . ARG D 1 79  ? 62.113  -4.288  0.761   1.00 31.42  ? 79  ARG D CB  1 
ATOM   7436  C  CG  . ARG D 1 79  ? 63.143  -4.535  1.842   1.00 31.50  ? 79  ARG D CG  1 
ATOM   7437  C  CD  . ARG D 1 79  ? 64.156  -3.460  1.643   1.00 33.76  ? 79  ARG D CD  1 
ATOM   7438  N  NE  . ARG D 1 79  ? 63.510  -2.160  1.788   1.00 33.40  ? 79  ARG D NE  1 
ATOM   7439  C  CZ  . ARG D 1 79  ? 63.622  -1.443  2.882   1.00 35.24  ? 79  ARG D CZ  1 
ATOM   7440  N  NH1 . ARG D 1 79  ? 64.319  -1.830  3.939   1.00 40.08  ? 79  ARG D NH1 1 
ATOM   7441  N  NH2 . ARG D 1 79  ? 62.950  -0.343  2.951   1.00 38.56  ? 79  ARG D NH2 1 
ATOM   7442  N  N   . PRO D 1 80  ? 58.823  -4.547  1.028   1.00 42.83  ? 80  PRO D N   1 
ATOM   7443  C  CA  . PRO D 1 80  ? 57.722  -3.838  0.391   1.00 34.15  ? 80  PRO D CA  1 
ATOM   7444  C  C   . PRO D 1 80  ? 58.295  -2.740  -0.506  1.00 29.30  ? 80  PRO D C   1 
ATOM   7445  O  O   . PRO D 1 80  ? 59.210  -1.980  -0.137  1.00 27.77  ? 80  PRO D O   1 
ATOM   7446  C  CB  . PRO D 1 80  ? 56.972  -3.259  1.615   1.00 36.10  ? 80  PRO D CB  1 
ATOM   7447  C  CG  . PRO D 1 80  ? 57.356  -4.117  2.802   1.00 36.66  ? 80  PRO D CG  1 
ATOM   7448  C  CD  . PRO D 1 80  ? 58.780  -4.482  2.529   1.00 44.08  ? 80  PRO D CD  1 
ATOM   7449  N  N   . ALA D 1 81  ? 57.695  -2.615  -1.679  1.00 28.82  ? 81  ALA D N   1 
ATOM   7450  C  CA  . ALA D 1 81  ? 58.200  -1.735  -2.732  1.00 31.87  ? 81  ALA D CA  1 
ATOM   7451  C  C   . ALA D 1 81  ? 58.291  -0.301  -2.272  1.00 31.58  ? 81  ALA D C   1 
ATOM   7452  O  O   . ALA D 1 81  ? 59.195  0.400   -2.699  1.00 30.73  ? 81  ALA D O   1 
ATOM   7453  C  CB  . ALA D 1 81  ? 57.329  -1.843  -3.976  1.00 32.90  ? 81  ALA D CB  1 
ATOM   7454  N  N   . GLY D 1 82  ? 57.328  0.130   -1.426  1.00 33.36  ? 82  GLY D N   1 
ATOM   7455  C  CA  . GLY D 1 82  ? 57.135  1.534   -1.115  1.00 31.41  ? 82  GLY D CA  1 
ATOM   7456  C  C   . GLY D 1 82  ? 57.873  1.983   0.151   1.00 29.57  ? 82  GLY D C   1 
ATOM   7457  O  O   . GLY D 1 82  ? 57.823  3.156   0.486   1.00 31.76  ? 82  GLY D O   1 
ATOM   7458  N  N   . LEU D 1 83  ? 58.571  1.055   0.815   1.00 25.47  ? 83  LEU D N   1 
ATOM   7459  C  CA  . LEU D 1 83  ? 59.013  1.280   2.179   1.00 26.16  ? 83  LEU D CA  1 
ATOM   7460  C  C   . LEU D 1 83  ? 60.329  2.051   2.200   1.00 25.80  ? 83  LEU D C   1 
ATOM   7461  O  O   . LEU D 1 83  ? 61.296  1.547   1.673   1.00 25.77  ? 83  LEU D O   1 
ATOM   7462  C  CB  . LEU D 1 83  ? 59.116  -0.038  2.959   1.00 25.28  ? 83  LEU D CB  1 
ATOM   7463  C  CG  . LEU D 1 83  ? 59.535  0.082   4.425   1.00 26.16  ? 83  LEU D CG  1 
ATOM   7464  C  CD1 . LEU D 1 83  ? 58.636  1.000   5.233   1.00 28.43  ? 83  LEU D CD1 1 
ATOM   7465  C  CD2 . LEU D 1 83  ? 59.561  -1.328  4.984   1.00 29.77  ? 83  LEU D CD2 1 
ATOM   7466  N  N   . HIS D 1 84  ? 60.338  3.241   2.827   1.00 24.18  ? 84  HIS D N   1 
ATOM   7467  C  CA  . HIS D 1 84  ? 61.491  4.096   2.970   1.00 23.43  ? 84  HIS D CA  1 
ATOM   7468  C  C   . HIS D 1 84  ? 61.293  4.942   4.207   1.00 25.29  ? 84  HIS D C   1 
ATOM   7469  O  O   . HIS D 1 84  ? 60.193  4.977   4.732   1.00 23.34  ? 84  HIS D O   1 
ATOM   7470  C  CB  . HIS D 1 84  ? 61.698  4.994   1.742   1.00 23.87  ? 84  HIS D CB  1 
ATOM   7471  C  CG  . HIS D 1 84  ? 60.478  5.674   1.250   1.00 25.58  ? 84  HIS D CG  1 
ATOM   7472  N  ND1 . HIS D 1 84  ? 59.739  5.209   0.170   1.00 28.33  ? 84  HIS D ND1 1 
ATOM   7473  C  CD2 . HIS D 1 84  ? 59.861  6.810   1.709   1.00 26.46  ? 84  HIS D CD2 1 
ATOM   7474  C  CE1 . HIS D 1 84  ? 58.679  6.019   0.012   1.00 30.47  ? 84  HIS D CE1 1 
ATOM   7475  N  NE2 . HIS D 1 84  ? 58.742  7.010   0.919   1.00 27.44  ? 84  HIS D NE2 1 
ATOM   7476  N  N   . PRO D 1 85  ? 62.350  5.627   4.703   1.00 26.61  ? 85  PRO D N   1 
ATOM   7477  C  CA  . PRO D 1 85  ? 62.206  6.481   5.873   1.00 27.25  ? 85  PRO D CA  1 
ATOM   7478  C  C   . PRO D 1 85  ? 61.362  7.676   5.468   1.00 27.68  ? 85  PRO D C   1 
ATOM   7479  O  O   . PRO D 1 85  ? 61.382  8.060   4.283   1.00 25.12  ? 85  PRO D O   1 
ATOM   7480  C  CB  . PRO D 1 85  ? 63.653  6.851   6.221   1.00 24.41  ? 85  PRO D CB  1 
ATOM   7481  C  CG  . PRO D 1 85  ? 64.423  5.773   5.540   1.00 26.85  ? 85  PRO D CG  1 
ATOM   7482  C  CD  . PRO D 1 85  ? 63.734  5.603   4.216   1.00 25.18  ? 85  PRO D CD  1 
ATOM   7483  N  N   . PHE D 1 86  ? 60.626  8.209   6.457   1.00 23.05  ? 86  PHE D N   1 
ATOM   7484  C  CA  . PHE D 1 86  ? 59.814  9.380   6.222   1.00 23.51  ? 86  PHE D CA  1 
ATOM   7485  C  C   . PHE D 1 86  ? 60.775  10.431  5.714   1.00 27.93  ? 86  PHE D C   1 
ATOM   7486  O  O   . PHE D 1 86  ? 61.852  10.529  6.278   1.00 24.93  ? 86  PHE D O   1 
ATOM   7487  C  CB  . PHE D 1 86  ? 59.143  9.789   7.524   1.00 24.05  ? 86  PHE D CB  1 
ATOM   7488  C  CG  . PHE D 1 86  ? 58.281  11.033  7.497   1.00 23.65  ? 86  PHE D CG  1 
ATOM   7489  C  CD1 . PHE D 1 86  ? 58.835  12.277  7.627   1.00 25.27  ? 86  PHE D CD1 1 
ATOM   7490  C  CD2 . PHE D 1 86  ? 56.915  10.935  7.340   1.00 29.53  ? 86  PHE D CD2 1 
ATOM   7491  C  CE1 . PHE D 1 86  ? 58.031  13.425  7.534   1.00 29.85  ? 86  PHE D CE1 1 
ATOM   7492  C  CE2 . PHE D 1 86  ? 56.093  12.068  7.298   1.00 32.38  ? 86  PHE D CE2 1 
ATOM   7493  C  CZ  . PHE D 1 86  ? 56.652  13.317  7.398   1.00 30.36  ? 86  PHE D CZ  1 
ATOM   7494  N  N   . ARG D 1 87  ? 60.363  11.210  4.698   1.00 34.71  ? 87  ARG D N   1 
ATOM   7495  C  CA  . ARG D 1 87  ? 61.203  12.278  4.188   1.00 34.37  ? 87  ARG D CA  1 
ATOM   7496  C  C   . ARG D 1 87  ? 60.809  13.613  4.811   1.00 30.77  ? 87  ARG D C   1 
ATOM   7497  O  O   . ARG D 1 87  ? 59.653  14.038  4.676   1.00 29.16  ? 87  ARG D O   1 
ATOM   7498  C  CB  . ARG D 1 87  ? 60.874  12.510  2.718   1.00 45.20  ? 87  ARG D CB  1 
ATOM   7499  C  CG  . ARG D 1 87  ? 60.997  11.383  1.720   1.00 63.45  ? 87  ARG D CG  1 
ATOM   7500  C  CD  . ARG D 1 87  ? 60.471  12.038  0.385   1.00 75.17  ? 87  ARG D CD  1 
ATOM   7501  N  NE  . ARG D 1 87  ? 60.995  10.979  -0.473  1.00 77.06  ? 87  ARG D NE  1 
ATOM   7502  C  CZ  . ARG D 1 87  ? 60.354  9.916   -0.893  1.00 65.91  ? 87  ARG D CZ  1 
ATOM   7503  N  NH1 . ARG D 1 87  ? 59.080  10.027  -1.223  1.00 74.92  ? 87  ARG D NH1 1 
ATOM   7504  N  NH2 . ARG D 1 87  ? 61.046  8.804   -1.104  1.00 60.00  ? 87  ARG D NH2 1 
ATOM   7505  N  N   . GLU D 1 88  ? 61.800  14.293  5.403   1.00 29.73  ? 88  GLU D N   1 
ATOM   7506  C  CA  . GLU D 1 88  ? 61.665  15.628  5.944   1.00 28.39  ? 88  GLU D CA  1 
ATOM   7507  C  C   . GLU D 1 88  ? 61.275  16.569  4.826   1.00 29.38  ? 88  GLU D C   1 
ATOM   7508  O  O   . GLU D 1 88  ? 61.734  16.387  3.719   1.00 30.27  ? 88  GLU D O   1 
ATOM   7509  C  CB  . GLU D 1 88  ? 62.985  16.183  6.414   1.00 31.87  ? 88  GLU D CB  1 
ATOM   7510  C  CG  . GLU D 1 88  ? 63.380  15.680  7.779   1.00 50.04  ? 88  GLU D CG  1 
ATOM   7511  C  CD  . GLU D 1 88  ? 64.036  16.718  8.680   1.00 65.16  ? 88  GLU D CD  1 
ATOM   7512  O  OE1 . GLU D 1 88  ? 64.502  17.846  8.245   1.00 46.34  ? 88  GLU D OE1 1 
ATOM   7513  O  OE2 . GLU D 1 88  ? 63.989  16.296  9.895   1.00 56.91  ? 88  GLU D OE2 1 
ATOM   7514  N  N   . LEU D 1 89  ? 60.414  17.551  5.089   1.00 25.19  ? 89  LEU D N   1 
ATOM   7515  C  CA  . LEU D 1 89  ? 60.066  18.541  4.098   1.00 22.80  ? 89  LEU D CA  1 
ATOM   7516  C  C   . LEU D 1 89  ? 60.372  19.885  4.733   1.00 25.42  ? 89  LEU D C   1 
ATOM   7517  O  O   . LEU D 1 89  ? 59.813  20.259  5.786   1.00 24.94  ? 89  LEU D O   1 
ATOM   7518  C  CB  . LEU D 1 89  ? 58.599  18.442  3.706   1.00 26.00  ? 89  LEU D CB  1 
ATOM   7519  C  CG  . LEU D 1 89  ? 58.072  17.109  3.157   1.00 29.52  ? 89  LEU D CG  1 
ATOM   7520  C  CD1 . LEU D 1 89  ? 56.582  17.170  2.859   1.00 28.35  ? 89  LEU D CD1 1 
ATOM   7521  C  CD2 . LEU D 1 89  ? 58.721  16.699  1.903   1.00 29.96  ? 89  LEU D CD2 1 
ATOM   7522  N  N   . ASP D 1 90  ? 61.303  20.609  4.086   1.00 28.01  ? 90  ASP D N   1 
ATOM   7523  C  CA  . ASP D 1 90  ? 61.822  21.858  4.631   1.00 30.33  ? 90  ASP D CA  1 
ATOM   7524  C  C   . ASP D 1 90  ? 61.214  22.953  3.772   1.00 26.93  ? 90  ASP D C   1 
ATOM   7525  O  O   . ASP D 1 90  ? 61.672  23.251  2.686   1.00 30.53  ? 90  ASP D O   1 
ATOM   7526  C  CB  . ASP D 1 90  ? 63.340  21.779  4.772   1.00 32.31  ? 90  ASP D CB  1 
ATOM   7527  C  CG  . ASP D 1 90  ? 63.917  22.774  5.765   1.00 46.17  ? 90  ASP D CG  1 
ATOM   7528  O  OD1 . ASP D 1 90  ? 63.450  22.876  6.912   1.00 61.69  ? 90  ASP D OD1 1 
ATOM   7529  O  OD2 . ASP D 1 90  ? 64.791  23.518  5.365   1.00 55.83  ? 90  ASP D OD2 1 
ATOM   7530  N  N   . GLY D 1 91  ? 60.070  23.438  4.168   1.00 27.00  ? 91  GLY D N   1 
ATOM   7531  C  CA  . GLY D 1 91  ? 59.348  24.368  3.298   1.00 27.96  ? 91  GLY D CA  1 
ATOM   7532  C  C   . GLY D 1 91  ? 59.794  25.808  3.592   1.00 26.36  ? 91  GLY D C   1 
ATOM   7533  O  O   . GLY D 1 91  ? 60.524  26.057  4.550   1.00 27.30  ? 91  GLY D O   1 
ATOM   7534  N  N   . PRO D 1 92  ? 59.384  26.787  2.762   1.00 21.90  ? 92  PRO D N   1 
ATOM   7535  C  CA  . PRO D 1 92  ? 59.776  28.163  2.970   1.00 22.22  ? 92  PRO D CA  1 
ATOM   7536  C  C   . PRO D 1 92  ? 59.389  28.617  4.360   1.00 25.22  ? 92  PRO D C   1 
ATOM   7537  O  O   . PRO D 1 92  ? 60.132  29.361  4.966   1.00 32.98  ? 92  PRO D O   1 
ATOM   7538  C  CB  . PRO D 1 92  ? 59.030  28.972  1.937   1.00 25.46  ? 92  PRO D CB  1 
ATOM   7539  C  CG  . PRO D 1 92  ? 58.369  27.958  1.001   1.00 28.02  ? 92  PRO D CG  1 
ATOM   7540  C  CD  . PRO D 1 92  ? 58.578  26.563  1.575   1.00 26.23  ? 92  PRO D CD  1 
ATOM   7541  N  N   . VAL D 1 93  ? 58.212  28.202  4.869   1.00 28.91  ? 93  VAL D N   1 
ATOM   7542  C  CA  . VAL D 1 93  ? 57.714  28.642  6.168   1.00 22.98  ? 93  VAL D CA  1 
ATOM   7543  C  C   . VAL D 1 93  ? 57.596  27.432  7.089   1.00 24.59  ? 93  VAL D C   1 
ATOM   7544  O  O   . VAL D 1 93  ? 57.996  27.530  8.228   1.00 28.70  ? 93  VAL D O   1 
ATOM   7545  C  CB  . VAL D 1 93  ? 56.354  29.357  6.095   1.00 22.27  ? 93  VAL D CB  1 
ATOM   7546  C  CG1 . VAL D 1 93  ? 55.795  29.622  7.498   1.00 22.16  ? 93  VAL D CG1 1 
ATOM   7547  C  CG2 . VAL D 1 93  ? 56.417  30.585  5.192   1.00 20.06  ? 93  VAL D CG2 1 
ATOM   7548  N  N   . HIS D 1 94  ? 57.038  26.309  6.649   1.00 21.71  ? 94  HIS D N   1 
ATOM   7549  C  CA  . HIS D 1 94  ? 56.709  25.226  7.570   1.00 22.00  ? 94  HIS D CA  1 
ATOM   7550  C  C   . HIS D 1 94  ? 57.535  23.986  7.255   1.00 21.88  ? 94  HIS D C   1 
ATOM   7551  O  O   . HIS D 1 94  ? 57.830  23.713  6.112   1.00 22.46  ? 94  HIS D O   1 
ATOM   7552  C  CB  . HIS D 1 94  ? 55.207  24.884  7.562   1.00 22.34  ? 94  HIS D CB  1 
ATOM   7553  C  CG  . HIS D 1 94  ? 54.289  26.006  7.906   1.00 21.85  ? 94  HIS D CG  1 
ATOM   7554  N  ND1 . HIS D 1 94  ? 54.248  26.503  9.179   1.00 23.89  ? 94  HIS D ND1 1 
ATOM   7555  C  CD2 . HIS D 1 94  ? 53.435  26.759  7.206   1.00 22.75  ? 94  HIS D CD2 1 
ATOM   7556  C  CE1 . HIS D 1 94  ? 53.322  27.468  9.237   1.00 24.55  ? 94  HIS D CE1 1 
ATOM   7557  N  NE2 . HIS D 1 94  ? 52.832  27.640  8.061   1.00 20.21  ? 94  HIS D NE2 1 
ATOM   7558  N  N   . ARG D 1 95  ? 57.857  23.191  8.279   1.00 23.10  ? 95  ARG D N   1 
ATOM   7559  C  CA  . ARG D 1 95  ? 58.708  22.023  8.129   1.00 29.41  ? 95  ARG D CA  1 
ATOM   7560  C  C   . ARG D 1 95  ? 58.046  20.780  8.713   1.00 26.93  ? 95  ARG D C   1 
ATOM   7561  O  O   . ARG D 1 95  ? 57.439  20.831  9.776   1.00 22.19  ? 95  ARG D O   1 
ATOM   7562  C  CB  . ARG D 1 95  ? 59.873  22.563  8.946   1.00 42.44  ? 95  ARG D CB  1 
ATOM   7563  C  CG  . ARG D 1 95  ? 61.056  21.723  9.358   1.00 57.16  ? 95  ARG D CG  1 
ATOM   7564  C  CD  . ARG D 1 95  ? 62.004  22.866  9.951   1.00 66.25  ? 95  ARG D CD  1 
ATOM   7565  N  NE  . ARG D 1 95  ? 63.276  22.166  9.797   1.00 76.04  ? 95  ARG D NE  1 
ATOM   7566  C  CZ  . ARG D 1 95  ? 63.443  20.978  10.385  1.00 87.82  ? 95  ARG D CZ  1 
ATOM   7567  N  NH1 . ARG D 1 95  ? 63.139  20.839  11.687  1.00 79.27  ? 95  ARG D NH1 1 
ATOM   7568  N  NH2 . ARG D 1 95  ? 64.017  19.996  9.680   1.00 84.82  ? 95  ARG D NH2 1 
ATOM   7569  N  N   . ALA D 1 96  ? 58.106  19.686  7.961   1.00 26.62  ? 96  ALA D N   1 
ATOM   7570  C  CA  . ALA D 1 96  ? 57.654  18.392  8.417   1.00 22.98  ? 96  ALA D CA  1 
ATOM   7571  C  C   . ALA D 1 96  ? 58.875  17.566  8.814   1.00 23.75  ? 96  ALA D C   1 
ATOM   7572  O  O   . ALA D 1 96  ? 59.701  17.142  7.990   1.00 27.72  ? 96  ALA D O   1 
ATOM   7573  C  CB  . ALA D 1 96  ? 56.878  17.753  7.314   1.00 25.24  ? 96  ALA D CB  1 
ATOM   7574  N  N   . VAL D 1 97  ? 59.050  17.415  10.120  1.00 25.82  ? 97  VAL D N   1 
ATOM   7575  C  CA  . VAL D 1 97  ? 60.222  16.760  10.695  1.00 24.86  ? 97  VAL D CA  1 
ATOM   7576  C  C   . VAL D 1 97  ? 60.054  15.268  10.553  1.00 24.01  ? 97  VAL D C   1 
ATOM   7577  O  O   . VAL D 1 97  ? 58.908  14.800  10.542  1.00 23.98  ? 97  VAL D O   1 
ATOM   7578  C  CB  . VAL D 1 97  ? 60.422  17.101  12.166  1.00 24.54  ? 97  VAL D CB  1 
ATOM   7579  C  CG1 . VAL D 1 97  ? 60.587  18.606  12.308  1.00 29.67  ? 97  VAL D CG1 1 
ATOM   7580  C  CG2 . VAL D 1 97  ? 59.217  16.655  13.004  1.00 26.09  ? 97  VAL D CG2 1 
ATOM   7581  N  N   . ALA D 1 98  ? 61.195  14.581  10.483  1.00 21.04  ? 98  ALA D N   1 
ATOM   7582  C  CA  . ALA D 1 98  ? 61.215  13.130  10.550  1.00 22.86  ? 98  ALA D CA  1 
ATOM   7583  C  C   . ALA D 1 98  ? 61.759  12.689  11.894  1.00 23.70  ? 98  ALA D C   1 
ATOM   7584  O  O   . ALA D 1 98  ? 62.815  13.136  12.255  1.00 22.85  ? 98  ALA D O   1 
ATOM   7585  C  CB  . ALA D 1 98  ? 62.090  12.608  9.487   1.00 22.13  ? 98  ALA D CB  1 
ATOM   7586  N  N   . THR D 1 99  ? 61.083  11.807  12.626  1.00 22.90  ? 99  THR D N   1 
ATOM   7587  C  CA  . THR D 1 99  ? 61.551  11.451  13.935  1.00 21.09  ? 99  THR D CA  1 
ATOM   7588  C  C   . THR D 1 99  ? 61.629  9.940   13.975  1.00 21.03  ? 99  THR D C   1 
ATOM   7589  O  O   . THR D 1 99  ? 61.089  9.255   13.142  1.00 22.12  ? 99  THR D O   1 
ATOM   7590  C  CB  . THR D 1 99  ? 60.648  12.003  15.031  1.00 25.75  ? 99  THR D CB  1 
ATOM   7591  O  OG1 . THR D 1 99  ? 59.350  11.457  14.802  1.00 23.43  ? 99  THR D OG1 1 
ATOM   7592  C  CG2 . THR D 1 99  ? 60.697  13.525  15.085  1.00 23.77  ? 99  THR D CG2 1 
ATOM   7593  N  N   . PRO D 1 100 ? 62.459  9.383   14.846  1.00 22.39  ? 100 PRO D N   1 
ATOM   7594  C  CA  . PRO D 1 100 ? 62.730  7.942   14.766  1.00 21.85  ? 100 PRO D CA  1 
ATOM   7595  C  C   . PRO D 1 100 ? 61.542  7.103   15.220  1.00 24.90  ? 100 PRO D C   1 
ATOM   7596  O  O   . PRO D 1 100 ? 60.835  7.458   16.184  1.00 30.26  ? 100 PRO D O   1 
ATOM   7597  C  CB  . PRO D 1 100 ? 63.903  7.759   15.692  1.00 22.81  ? 100 PRO D CB  1 
ATOM   7598  C  CG  . PRO D 1 100 ? 63.994  9.019   16.551  1.00 23.07  ? 100 PRO D CG  1 
ATOM   7599  C  CD  . PRO D 1 100 ? 63.176  10.131  15.892  1.00 23.00  ? 100 PRO D CD  1 
ATOM   7600  N  N   . GLY D 1 101 ? 61.433  5.926   14.607  1.00 23.36  ? 101 GLY D N   1 
ATOM   7601  C  CA  . GLY D 1 101 ? 60.435  4.955   14.957  1.00 22.84  ? 101 GLY D CA  1 
ATOM   7602  C  C   . GLY D 1 101 ? 60.636  3.668   14.165  1.00 21.85  ? 101 GLY D C   1 
ATOM   7603  O  O   . GLY D 1 101 ? 60.615  3.661   12.942  1.00 26.14  ? 101 GLY D O   1 
ATOM   7604  N  N   . ASP D 1 102 ? 60.665  2.543   14.866  1.00 21.55  ? 102 ASP D N   1 
ATOM   7605  C  CA  . ASP D 1 102 ? 60.837  1.270   14.220  1.00 21.81  ? 102 ASP D CA  1 
ATOM   7606  C  C   . ASP D 1 102 ? 59.517  0.527   14.155  1.00 21.13  ? 102 ASP D C   1 
ATOM   7607  O  O   . ASP D 1 102 ? 59.285  -0.213  13.239  1.00 23.65  ? 102 ASP D O   1 
ATOM   7608  C  CB  . ASP D 1 102 ? 61.928  0.453   14.924  1.00 25.29  ? 102 ASP D CB  1 
ATOM   7609  C  CG  . ASP D 1 102 ? 63.333  1.068   14.857  1.00 27.62  ? 102 ASP D CG  1 
ATOM   7610  O  OD1 . ASP D 1 102 ? 63.660  1.692   13.805  1.00 28.69  ? 102 ASP D OD1 1 
ATOM   7611  O  OD2 . ASP D 1 102 ? 64.102  0.890   15.814  1.00 26.99  ? 102 ASP D OD2 1 
ATOM   7612  N  N   . LEU D 1 103 ? 58.746  0.570   15.213  1.00 25.00  ? 103 LEU D N   1 
ATOM   7613  C  CA  . LEU D 1 103 ? 57.477  -0.129  15.318  1.00 24.81  ? 103 LEU D CA  1 
ATOM   7614  C  C   . LEU D 1 103 ? 56.396  0.858   15.749  1.00 21.51  ? 103 LEU D C   1 
ATOM   7615  O  O   . LEU D 1 103 ? 56.620  1.738   16.595  1.00 21.41  ? 103 LEU D O   1 
ATOM   7616  C  CB  . LEU D 1 103 ? 57.528  -1.228  16.373  1.00 27.60  ? 103 LEU D CB  1 
ATOM   7617  C  CG  . LEU D 1 103 ? 58.482  -2.385  16.120  1.00 28.37  ? 103 LEU D CG  1 
ATOM   7618  C  CD1 . LEU D 1 103 ? 58.368  -3.317  17.362  1.00 30.04  ? 103 LEU D CD1 1 
ATOM   7619  C  CD2 . LEU D 1 103 ? 58.075  -3.068  14.866  1.00 30.65  ? 103 LEU D CD2 1 
ATOM   7620  N  N   . LEU D 1 104 ? 55.229  0.672   15.137  1.00 22.93  ? 104 LEU D N   1 
ATOM   7621  C  CA  . LEU D 1 104 ? 54.015  1.391   15.474  1.00 23.53  ? 104 LEU D CA  1 
ATOM   7622  C  C   . LEU D 1 104 ? 52.982  0.374   15.954  1.00 23.68  ? 104 LEU D C   1 
ATOM   7623  O  O   . LEU D 1 104 ? 52.762  -0.631  15.281  1.00 24.71  ? 104 LEU D O   1 
ATOM   7624  C  CB  . LEU D 1 104 ? 53.498  2.111   14.231  1.00 26.46  ? 104 LEU D CB  1 
ATOM   7625  C  CG  . LEU D 1 104 ? 52.046  2.633   14.284  1.00 25.07  ? 104 LEU D CG  1 
ATOM   7626  C  CD1 . LEU D 1 104 ? 52.062  3.893   15.123  1.00 25.77  ? 104 LEU D CD1 1 
ATOM   7627  C  CD2 . LEU D 1 104 ? 51.535  2.869   12.914  1.00 23.76  ? 104 LEU D CD2 1 
ATOM   7628  N  N   . PHE D 1 105 ? 52.347  0.676   17.086  1.00 24.64  ? 105 PHE D N   1 
ATOM   7629  C  CA  . PHE D 1 105 ? 51.111  0.002   17.474  1.00 25.43  ? 105 PHE D CA  1 
ATOM   7630  C  C   . PHE D 1 105 ? 49.970  1.038   17.495  1.00 20.26  ? 105 PHE D C   1 
ATOM   7631  O  O   . PHE D 1 105 ? 50.035  2.001   18.258  1.00 18.06  ? 105 PHE D O   1 
ATOM   7632  C  CB  . PHE D 1 105 ? 51.286  -0.714  18.827  1.00 24.21  ? 105 PHE D CB  1 
ATOM   7633  C  CG  . PHE D 1 105 ? 52.395  -1.735  18.819  1.00 23.11  ? 105 PHE D CG  1 
ATOM   7634  C  CD1 . PHE D 1 105 ? 52.208  -2.999  18.302  1.00 21.74  ? 105 PHE D CD1 1 
ATOM   7635  C  CD2 . PHE D 1 105 ? 53.645  -1.402  19.314  1.00 29.69  ? 105 PHE D CD2 1 
ATOM   7636  C  CE1 . PHE D 1 105 ? 53.239  -3.917  18.262  1.00 20.71  ? 105 PHE D CE1 1 
ATOM   7637  C  CE2 . PHE D 1 105 ? 54.699  -2.315  19.254  1.00 27.18  ? 105 PHE D CE2 1 
ATOM   7638  C  CZ  . PHE D 1 105 ? 54.470  -3.577  18.723  1.00 24.81  ? 105 PHE D CZ  1 
ATOM   7639  N  N   . HIS D 1 106 ? 49.029  0.872   16.576  1.00 17.93  ? 106 HIS D N   1 
ATOM   7640  C  CA  . HIS D 1 106 ? 47.837  1.696   16.468  1.00 18.82  ? 106 HIS D CA  1 
ATOM   7641  C  C   . HIS D 1 106 ? 46.672  0.907   17.061  1.00 17.91  ? 106 HIS D C   1 
ATOM   7642  O  O   . HIS D 1 106 ? 46.161  -0.013  16.450  1.00 15.34  ? 106 HIS D O   1 
ATOM   7643  C  CB  . HIS D 1 106 ? 47.579  2.063   15.010  1.00 18.97  ? 106 HIS D CB  1 
ATOM   7644  C  CG  . HIS D 1 106 ? 46.397  2.970   14.795  1.00 22.41  ? 106 HIS D CG  1 
ATOM   7645  N  ND1 . HIS D 1 106 ? 45.698  3.014   13.598  1.00 22.00  ? 106 HIS D ND1 1 
ATOM   7646  C  CD2 . HIS D 1 106 ? 45.803  3.835   15.603  1.00 22.73  ? 106 HIS D CD2 1 
ATOM   7647  C  CE1 . HIS D 1 106 ? 44.759  3.922   13.686  1.00 21.70  ? 106 HIS D CE1 1 
ATOM   7648  N  NE2 . HIS D 1 106 ? 44.811  4.466   14.877  1.00 22.97  ? 106 HIS D NE2 1 
ATOM   7649  N  N   . ILE D 1 107 ? 46.359  1.238   18.304  1.00 20.72  ? 107 ILE D N   1 
ATOM   7650  C  CA  . ILE D 1 107 ? 45.400  0.479   19.086  1.00 22.24  ? 107 ILE D CA  1 
ATOM   7651  C  C   . ILE D 1 107 ? 44.126  1.302   19.233  1.00 18.11  ? 107 ILE D C   1 
ATOM   7652  O  O   . ILE D 1 107 ? 44.196  2.451   19.674  1.00 17.37  ? 107 ILE D O   1 
ATOM   7653  C  CB  . ILE D 1 107 ? 46.008  0.142   20.458  1.00 22.70  ? 107 ILE D CB  1 
ATOM   7654  C  CG1 . ILE D 1 107 ? 47.305  -0.643  20.326  1.00 20.60  ? 107 ILE D CG1 1 
ATOM   7655  C  CG2 . ILE D 1 107 ? 45.023  -0.663  21.288  1.00 24.13  ? 107 ILE D CG2 1 
ATOM   7656  C  CD1 . ILE D 1 107 ? 48.096  -0.677  21.621  1.00 25.15  ? 107 ILE D CD1 1 
ATOM   7657  N  N   . ARG D 1 108 ? 43.001  0.695   18.845  1.00 19.84  ? 108 ARG D N   1 
ATOM   7658  C  CA  . ARG D 1 108 ? 41.745  1.399   18.831  1.00 21.03  ? 108 ARG D CA  1 
ATOM   7659  C  C   . ARG D 1 108 ? 40.687  0.557   19.493  1.00 22.60  ? 108 ARG D C   1 
ATOM   7660  O  O   . ARG D 1 108 ? 40.674  -0.655  19.324  1.00 19.31  ? 108 ARG D O   1 
ATOM   7661  C  CB  . ARG D 1 108 ? 41.324  1.680   17.389  1.00 22.22  ? 108 ARG D CB  1 
ATOM   7662  C  CG  . ARG D 1 108 ? 42.085  2.841   16.746  1.00 21.24  ? 108 ARG D CG  1 
ATOM   7663  C  CD  . ARG D 1 108 ? 41.712  3.001   15.293  1.00 23.54  ? 108 ARG D CD  1 
ATOM   7664  N  NE  . ARG D 1 108 ? 42.049  1.861   14.444  1.00 22.39  ? 108 ARG D NE  1 
ATOM   7665  C  CZ  . ARG D 1 108 ? 42.032  1.923   13.121  1.00 26.66  ? 108 ARG D CZ  1 
ATOM   7666  N  NH1 . ARG D 1 108 ? 41.558  2.988   12.541  1.00 26.50  ? 108 ARG D NH1 1 
ATOM   7667  N  NH2 . ARG D 1 108 ? 42.468  0.953   12.343  1.00 27.96  ? 108 ARG D NH2 1 
ATOM   7668  N  N   . ALA D 1 109 ? 39.763  1.224   20.180  1.00 26.27  ? 109 ALA D N   1 
ATOM   7669  C  CA  . ALA D 1 109 ? 38.584  0.552   20.719  1.00 26.13  ? 109 ALA D CA  1 
ATOM   7670  C  C   . ALA D 1 109 ? 37.535  1.581   21.096  1.00 28.56  ? 109 ALA D C   1 
ATOM   7671  O  O   . ALA D 1 109 ? 37.789  2.791   21.058  1.00 25.86  ? 109 ALA D O   1 
ATOM   7672  C  CB  . ALA D 1 109 ? 38.984  -0.183  21.951  1.00 28.51  ? 109 ALA D CB  1 
ATOM   7673  N  N   . SER D 1 110 ? 36.400  1.078   21.613  1.00 34.08  ? 110 SER D N   1 
ATOM   7674  C  CA  . SER D 1 110 ? 35.337  1.978   22.045  1.00 33.11  ? 110 SER D CA  1 
ATOM   7675  C  C   . SER D 1 110 ? 35.623  2.552   23.425  1.00 32.04  ? 110 SER D C   1 
ATOM   7676  O  O   . SER D 1 110 ? 35.016  3.520   23.802  1.00 31.03  ? 110 SER D O   1 
ATOM   7677  C  CB  . SER D 1 110 ? 34.028  1.330   21.970  1.00 33.62  ? 110 SER D CB  1 
ATOM   7678  O  OG  . SER D 1 110 ? 34.008  0.296   22.941  1.00 44.49  ? 110 SER D OG  1 
ATOM   7679  N  N   . ARG D 1 111 ? 36.638  2.052   24.143  1.00 36.75  ? 111 ARG D N   1 
ATOM   7680  C  CA  . ARG D 1 111 ? 36.934  2.525   25.491  1.00 32.71  ? 111 ARG D CA  1 
ATOM   7681  C  C   . ARG D 1 111 ? 38.450  2.477   25.687  1.00 27.91  ? 111 ARG D C   1 
ATOM   7682  O  O   . ARG D 1 111 ? 39.108  1.545   25.171  1.00 27.11  ? 111 ARG D O   1 
ATOM   7683  C  CB  . ARG D 1 111 ? 36.399  1.597   26.608  1.00 39.49  ? 111 ARG D CB  1 
ATOM   7684  C  CG  . ARG D 1 111 ? 35.097  0.798   26.554  1.00 40.80  ? 111 ARG D CG  1 
ATOM   7685  C  CD  . ARG D 1 111 ? 34.833  -0.413  27.549  1.00 42.33  ? 111 ARG D CD  1 
ATOM   7686  N  NE  . ARG D 1 111 ? 35.095  -0.070  28.963  1.00 58.66  ? 111 ARG D NE  1 
ATOM   7687  C  CZ  . ARG D 1 111 ? 34.619  0.856   29.870  1.00 44.24  ? 111 ARG D CZ  1 
ATOM   7688  N  NH1 . ARG D 1 111 ? 33.707  1.708   29.565  1.00 45.59  ? 111 ARG D NH1 1 
ATOM   7689  N  NH2 . ARG D 1 111 ? 35.029  0.938   31.130  1.00 42.51  ? 111 ARG D NH2 1 
ATOM   7690  N  N   . LEU D 1 112 ? 38.965  3.435   26.470  1.00 23.26  ? 112 LEU D N   1 
ATOM   7691  C  CA  . LEU D 1 112 ? 40.387  3.547   26.621  1.00 24.36  ? 112 LEU D CA  1 
ATOM   7692  C  C   . LEU D 1 112 ? 41.011  2.354   27.352  1.00 30.51  ? 112 LEU D C   1 
ATOM   7693  O  O   . LEU D 1 112 ? 42.165  1.970   27.138  1.00 35.52  ? 112 LEU D O   1 
ATOM   7694  C  CB  . LEU D 1 112 ? 40.670  4.878   27.277  1.00 25.13  ? 112 LEU D CB  1 
ATOM   7695  C  CG  . LEU D 1 112 ? 42.157  5.196   27.385  1.00 31.08  ? 112 LEU D CG  1 
ATOM   7696  C  CD1 . LEU D 1 112 ? 42.715  5.257   26.002  1.00 34.31  ? 112 LEU D CD1 1 
ATOM   7697  C  CD2 . LEU D 1 112 ? 42.445  6.504   28.063  1.00 40.76  ? 112 LEU D CD2 1 
ATOM   7698  N  N   . ASP D 1 113 ? 40.256  1.724   28.224  1.00 30.79  ? 113 ASP D N   1 
ATOM   7699  C  CA  . ASP D 1 113 ? 40.834  0.739   29.118  1.00 29.37  ? 113 ASP D CA  1 
ATOM   7700  C  C   . ASP D 1 113 ? 41.197  -0.493  28.321  1.00 22.11  ? 113 ASP D C   1 
ATOM   7701  O  O   . ASP D 1 113 ? 42.173  -1.136  28.632  1.00 25.21  ? 113 ASP D O   1 
ATOM   7702  C  CB  . ASP D 1 113 ? 39.896  0.360   30.266  1.00 40.00  ? 113 ASP D CB  1 
ATOM   7703  C  CG  . ASP D 1 113 ? 38.498  -0.053  29.811  1.00 39.14  ? 113 ASP D CG  1 
ATOM   7704  O  OD1 . ASP D 1 113 ? 37.780  0.997   29.443  1.00 36.55  ? 113 ASP D OD1 1 
ATOM   7705  O  OD2 . ASP D 1 113 ? 38.154  -1.344  29.851  1.00 30.90  ? 113 ASP D OD2 1 
ATOM   7706  N  N   . LEU D 1 114 ? 40.413  -0.878  27.332  1.00 21.74  ? 114 LEU D N   1 
ATOM   7707  C  CA  . LEU D 1 114 ? 40.799  -1.973  26.459  1.00 23.27  ? 114 LEU D CA  1 
ATOM   7708  C  C   . LEU D 1 114 ? 42.102  -1.667  25.696  1.00 24.62  ? 114 LEU D C   1 
ATOM   7709  O  O   . LEU D 1 114 ? 42.923  -2.556  25.484  1.00 26.85  ? 114 LEU D O   1 
ATOM   7710  C  CB  . LEU D 1 114 ? 39.683  -2.222  25.457  1.00 27.80  ? 114 LEU D CB  1 
ATOM   7711  C  CG  . LEU D 1 114 ? 38.390  -2.861  25.983  1.00 34.20  ? 114 LEU D CG  1 
ATOM   7712  C  CD1 . LEU D 1 114 ? 37.387  -3.080  24.835  1.00 29.54  ? 114 LEU D CD1 1 
ATOM   7713  C  CD2 . LEU D 1 114 ? 38.692  -4.249  26.558  1.00 39.32  ? 114 LEU D CD2 1 
ATOM   7714  N  N   . CYS D 1 115 ? 42.241  -0.412  25.221  1.00 25.95  ? 115 CYS D N   1 
ATOM   7715  C  CA  . CYS D 1 115 ? 43.453  0.048   24.579  1.00 24.94  ? 115 CYS D CA  1 
ATOM   7716  C  C   . CYS D 1 115 ? 44.613  -0.129  25.541  1.00 21.54  ? 115 CYS D C   1 
ATOM   7717  O  O   . CYS D 1 115 ? 45.648  -0.652  25.160  1.00 23.92  ? 115 CYS D O   1 
ATOM   7718  C  CB  . CYS D 1 115 ? 43.378  1.509   24.121  1.00 23.69  ? 115 CYS D CB  1 
ATOM   7719  S  SG  . CYS D 1 115 ? 42.106  1.688   22.839  1.00 25.58  ? 115 CYS D SG  1 
ATOM   7720  N  N   . PHE D 1 116 ? 44.418  0.327   26.760  1.00 18.30  ? 116 PHE D N   1 
ATOM   7721  C  CA  . PHE D 1 116 ? 45.489  0.335   27.720  1.00 19.84  ? 116 PHE D CA  1 
ATOM   7722  C  C   . PHE D 1 116 ? 45.850  -1.070  28.120  1.00 20.83  ? 116 PHE D C   1 
ATOM   7723  O  O   . PHE D 1 116 ? 47.002  -1.394  28.311  1.00 18.64  ? 116 PHE D O   1 
ATOM   7724  C  CB  . PHE D 1 116 ? 45.109  1.191   28.908  1.00 21.63  ? 116 PHE D CB  1 
ATOM   7725  C  CG  . PHE D 1 116 ? 46.256  1.475   29.836  1.00 18.50  ? 116 PHE D CG  1 
ATOM   7726  C  CD1 . PHE D 1 116 ? 46.582  0.572   30.830  1.00 20.79  ? 116 PHE D CD1 1 
ATOM   7727  C  CD2 . PHE D 1 116 ? 46.961  2.639   29.741  1.00 22.44  ? 116 PHE D CD2 1 
ATOM   7728  C  CE1 . PHE D 1 116 ? 47.561  0.887   31.752  1.00 23.96  ? 116 PHE D CE1 1 
ATOM   7729  C  CE2 . PHE D 1 116 ? 48.033  2.920   30.587  1.00 23.03  ? 116 PHE D CE2 1 
ATOM   7730  C  CZ  . PHE D 1 116 ? 48.309  2.049   31.614  1.00 26.09  ? 116 PHE D CZ  1 
ATOM   7731  N  N   . ALA D 1 117 ? 44.882  -1.940  28.179  1.00 23.82  ? 117 ALA D N   1 
ATOM   7732  C  CA  . ALA D 1 117 ? 45.179  -3.304  28.590  1.00 28.32  ? 117 ALA D CA  1 
ATOM   7733  C  C   . ALA D 1 117 ? 46.036  -4.011  27.545  1.00 26.58  ? 117 ALA D C   1 
ATOM   7734  O  O   . ALA D 1 117 ? 46.985  -4.711  27.901  1.00 27.85  ? 117 ALA D O   1 
ATOM   7735  C  CB  . ALA D 1 117 ? 43.868  -4.058  28.862  1.00 32.04  ? 117 ALA D CB  1 
ATOM   7736  N  N   . LEU D 1 118 ? 45.691  -3.838  26.267  1.00 22.95  ? 118 LEU D N   1 
ATOM   7737  C  CA  . LEU D 1 118 ? 46.443  -4.433  25.186  1.00 22.45  ? 118 LEU D CA  1 
ATOM   7738  C  C   . LEU D 1 118 ? 47.863  -3.805  25.107  1.00 24.80  ? 118 LEU D C   1 
ATOM   7739  O  O   . LEU D 1 118 ? 48.873  -4.503  24.951  1.00 26.48  ? 118 LEU D O   1 
ATOM   7740  C  CB  . LEU D 1 118 ? 45.641  -4.316  23.900  1.00 21.18  ? 118 LEU D CB  1 
ATOM   7741  C  CG  . LEU D 1 118 ? 46.344  -4.946  22.710  1.00 26.15  ? 118 LEU D CG  1 
ATOM   7742  C  CD1 . LEU D 1 118 ? 46.718  -6.402  22.917  1.00 26.79  ? 118 LEU D CD1 1 
ATOM   7743  C  CD2 . LEU D 1 118 ? 45.548  -4.879  21.430  1.00 33.16  ? 118 LEU D CD2 1 
ATOM   7744  N  N   . ALA D 1 119 ? 47.958  -2.478  25.216  1.00 23.54  ? 119 ALA D N   1 
ATOM   7745  C  CA  . ALA D 1 119 ? 49.240  -1.795  25.241  1.00 22.86  ? 119 ALA D CA  1 
ATOM   7746  C  C   . ALA D 1 119 ? 50.137  -2.328  26.379  1.00 26.02  ? 119 ALA D C   1 
ATOM   7747  O  O   . ALA D 1 119 ? 51.338  -2.488  26.212  1.00 25.18  ? 119 ALA D O   1 
ATOM   7748  C  CB  . ALA D 1 119 ? 49.008  -0.307  25.357  1.00 21.35  ? 119 ALA D CB  1 
ATOM   7749  N  N   . THR D 1 120 ? 49.566  -2.575  27.554  1.00 25.24  ? 120 THR D N   1 
ATOM   7750  C  CA  . THR D 1 120 ? 50.289  -3.125  28.685  1.00 24.41  ? 120 THR D CA  1 
ATOM   7751  C  C   . THR D 1 120 ? 50.838  -4.487  28.325  1.00 22.82  ? 120 THR D C   1 
ATOM   7752  O  O   . THR D 1 120 ? 51.981  -4.750  28.620  1.00 24.58  ? 120 THR D O   1 
ATOM   7753  C  CB  . THR D 1 120 ? 49.346  -3.273  29.869  1.00 26.17  ? 120 THR D CB  1 
ATOM   7754  O  OG1 . THR D 1 120 ? 48.998  -1.987  30.365  1.00 24.16  ? 120 THR D OG1 1 
ATOM   7755  C  CG2 . THR D 1 120 ? 50.062  -3.843  31.070  1.00 32.69  ? 120 THR D CG2 1 
ATOM   7756  N  N   . GLU D 1 121 ? 50.024  -5.368  27.757  1.00 21.99  ? 121 GLU D N   1 
ATOM   7757  C  CA  . GLU D 1 121 ? 50.527  -6.691  27.414  1.00 25.11  ? 121 GLU D CA  1 
ATOM   7758  C  C   . GLU D 1 121 ? 51.675  -6.608  26.387  1.00 25.74  ? 121 GLU D C   1 
ATOM   7759  O  O   . GLU D 1 121 ? 52.617  -7.364  26.444  1.00 23.26  ? 121 GLU D O   1 
ATOM   7760  C  CB  . GLU D 1 121 ? 49.472  -7.615  26.808  1.00 29.48  ? 121 GLU D CB  1 
ATOM   7761  C  CG  . GLU D 1 121 ? 48.406  -8.022  27.807  1.00 36.45  ? 121 GLU D CG  1 
ATOM   7762  C  CD  . GLU D 1 121 ? 48.834  -9.080  28.811  1.00 37.79  ? 121 GLU D CD  1 
ATOM   7763  O  OE1 . GLU D 1 121 ? 49.872  -9.789  28.644  1.00 37.85  ? 121 GLU D OE1 1 
ATOM   7764  O  OE2 . GLU D 1 121 ? 48.029  -9.188  29.738  1.00 35.59  ? 121 GLU D OE2 1 
ATOM   7765  N  N   . ILE D 1 122 ? 51.543  -5.736  25.383  1.00 28.24  ? 122 ILE D N   1 
ATOM   7766  C  CA  . ILE D 1 122 ? 52.510  -5.650  24.313  1.00 27.50  ? 122 ILE D CA  1 
ATOM   7767  C  C   . ILE D 1 122 ? 53.827  -5.147  24.881  1.00 24.55  ? 122 ILE D C   1 
ATOM   7768  O  O   . ILE D 1 122 ? 54.857  -5.781  24.681  1.00 25.06  ? 122 ILE D O   1 
ATOM   7769  C  CB  . ILE D 1 122 ? 51.929  -4.819  23.166  1.00 25.94  ? 122 ILE D CB  1 
ATOM   7770  C  CG1 . ILE D 1 122 ? 50.961  -5.679  22.393  1.00 29.96  ? 122 ILE D CG1 1 
ATOM   7771  C  CG2 . ILE D 1 122 ? 52.987  -4.293  22.218  1.00 29.66  ? 122 ILE D CG2 1 
ATOM   7772  C  CD1 . ILE D 1 122 ? 50.099  -4.887  21.433  1.00 35.22  ? 122 ILE D CD1 1 
ATOM   7773  N  N   . MET D 1 123 ? 53.788  -4.066  25.639  1.00 23.62  ? 123 MET D N   1 
ATOM   7774  C  CA  . MET D 1 123 ? 55.004  -3.505  26.187  1.00 26.39  ? 123 MET D CA  1 
ATOM   7775  C  C   . MET D 1 123 ? 55.616  -4.371  27.275  1.00 28.94  ? 123 MET D C   1 
ATOM   7776  O  O   . MET D 1 123 ? 56.815  -4.349  27.463  1.00 33.31  ? 123 MET D O   1 
ATOM   7777  C  CB  . MET D 1 123 ? 54.757  -2.124  26.733  1.00 30.25  ? 123 MET D CB  1 
ATOM   7778  C  CG  . MET D 1 123 ? 54.561  -1.187  25.564  1.00 44.13  ? 123 MET D CG  1 
ATOM   7779  S  SD  . MET D 1 123 ? 56.100  -0.910  24.657  1.00 47.41  ? 123 MET D SD  1 
ATOM   7780  C  CE  . MET D 1 123 ? 57.192  -0.538  26.044  1.00 43.19  ? 123 MET D CE  1 
ATOM   7781  N  N   . GLY D 1 124 ? 54.807  -5.170  27.934  1.00 30.53  ? 124 GLY D N   1 
ATOM   7782  C  CA  . GLY D 1 124 ? 55.311  -6.119  28.904  1.00 27.85  ? 124 GLY D CA  1 
ATOM   7783  C  C   . GLY D 1 124 ? 56.151  -7.177  28.228  1.00 26.52  ? 124 GLY D C   1 
ATOM   7784  O  O   . GLY D 1 124 ? 57.116  -7.567  28.833  1.00 31.56  ? 124 GLY D O   1 
ATOM   7785  N  N   . ARG D 1 125 ? 55.811  -7.616  27.013  1.00 26.90  ? 125 ARG D N   1 
ATOM   7786  C  CA  . ARG D 1 125 ? 56.581  -8.597  26.292  1.00 26.69  ? 125 ARG D CA  1 
ATOM   7787  C  C   . ARG D 1 125 ? 57.836  -7.951  25.708  1.00 32.66  ? 125 ARG D C   1 
ATOM   7788  O  O   . ARG D 1 125 ? 58.754  -8.669  25.332  1.00 35.49  ? 125 ARG D O   1 
ATOM   7789  C  CB  . ARG D 1 125 ? 55.752  -9.270  25.210  1.00 30.97  ? 125 ARG D CB  1 
ATOM   7790  C  CG  . ARG D 1 125 ? 54.536  -10.003 25.765  1.00 39.54  ? 125 ARG D CG  1 
ATOM   7791  C  CD  . ARG D 1 125 ? 54.789  -11.485 25.800  1.00 43.53  ? 125 ARG D CD  1 
ATOM   7792  N  NE  . ARG D 1 125 ? 54.313  -12.292 24.662  1.00 43.15  ? 125 ARG D NE  1 
ATOM   7793  C  CZ  . ARG D 1 125 ? 55.071  -12.737 23.647  1.00 50.57  ? 125 ARG D CZ  1 
ATOM   7794  N  NH1 . ARG D 1 125 ? 56.338  -12.407 23.451  1.00 51.35  ? 125 ARG D NH1 1 
ATOM   7795  N  NH2 . ARG D 1 125 ? 54.525  -13.488 22.712  1.00 60.54  ? 125 ARG D NH2 1 
ATOM   7796  N  N   . LEU D 1 126 ? 57.898  -6.620  25.620  1.00 33.85  ? 126 LEU D N   1 
ATOM   7797  C  CA  . LEU D 1 126 ? 58.963  -5.957  24.876  1.00 31.45  ? 126 LEU D CA  1 
ATOM   7798  C  C   . LEU D 1 126 ? 59.918  -5.280  25.834  1.00 33.51  ? 126 LEU D C   1 
ATOM   7799  O  O   . LEU D 1 126 ? 60.865  -4.680  25.308  1.00 30.64  ? 126 LEU D O   1 
ATOM   7800  C  CB  . LEU D 1 126 ? 58.440  -4.895  23.892  1.00 28.11  ? 126 LEU D CB  1 
ATOM   7801  C  CG  . LEU D 1 126 ? 57.735  -5.437  22.634  1.00 29.68  ? 126 LEU D CG  1 
ATOM   7802  C  CD1 . LEU D 1 126 ? 57.289  -4.283  21.700  1.00 29.52  ? 126 LEU D CD1 1 
ATOM   7803  C  CD2 . LEU D 1 126 ? 58.443  -6.576  21.855  1.00 27.17  ? 126 LEU D CD2 1 
ATOM   7804  N  N   . ARG D 1 127 ? 59.624  -5.307  27.156  1.00 35.41  ? 127 ARG D N   1 
ATOM   7805  C  CA  . ARG D 1 127 ? 60.470  -4.719  28.187  1.00 43.16  ? 127 ARG D CA  1 
ATOM   7806  C  C   . ARG D 1 127 ? 61.929  -5.152  27.931  1.00 44.16  ? 127 ARG D C   1 
ATOM   7807  O  O   . ARG D 1 127 ? 62.259  -6.345  27.759  1.00 34.49  ? 127 ARG D O   1 
ATOM   7808  C  CB  . ARG D 1 127 ? 60.165  -5.176  29.625  1.00 53.79  ? 127 ARG D CB  1 
ATOM   7809  C  CG  . ARG D 1 127 ? 59.065  -4.566  30.480  1.00 69.46  ? 127 ARG D CG  1 
ATOM   7810  C  CD  . ARG D 1 127 ? 59.214  -3.070  30.839  1.00 78.46  ? 127 ARG D CD  1 
ATOM   7811  N  NE  . ARG D 1 127 ? 57.858  -2.513  31.006  1.00 102.10 ? 127 ARG D NE  1 
ATOM   7812  C  CZ  . ARG D 1 127 ? 57.198  -1.614  30.233  1.00 100.39 ? 127 ARG D CZ  1 
ATOM   7813  N  NH1 . ARG D 1 127 ? 55.876  -1.404  30.379  1.00 77.61  ? 127 ARG D NH1 1 
ATOM   7814  N  NH2 . ARG D 1 127 ? 57.849  -1.004  29.250  1.00 97.91  ? 127 ARG D NH2 1 
ATOM   7815  N  N   . GLY D 1 128 ? 62.830  -4.166  27.857  1.00 40.80  ? 128 GLY D N   1 
ATOM   7816  C  CA  . GLY D 1 128 ? 64.227  -4.520  27.743  1.00 46.75  ? 128 GLY D CA  1 
ATOM   7817  C  C   . GLY D 1 128 ? 64.687  -4.666  26.302  1.00 46.28  ? 128 GLY D C   1 
ATOM   7818  O  O   . GLY D 1 128 ? 65.880  -4.622  26.051  1.00 45.40  ? 128 GLY D O   1 
ATOM   7819  N  N   . ALA D 1 129 ? 63.772  -4.750  25.336  1.00 34.40  ? 129 ALA D N   1 
ATOM   7820  C  CA  . ALA D 1 129 ? 64.181  -4.855  23.945  1.00 29.18  ? 129 ALA D CA  1 
ATOM   7821  C  C   . ALA D 1 129 ? 63.913  -3.584  23.136  1.00 32.11  ? 129 ALA D C   1 
ATOM   7822  O  O   . ALA D 1 129 ? 64.358  -3.536  21.983  1.00 31.54  ? 129 ALA D O   1 
ATOM   7823  C  CB  . ALA D 1 129 ? 63.501  -6.029  23.317  1.00 24.59  ? 129 ALA D CB  1 
ATOM   7824  N  N   . VAL D 1 130 ? 63.108  -2.635  23.677  1.00 29.84  ? 130 VAL D N   1 
ATOM   7825  C  CA  . VAL D 1 130 ? 62.710  -1.473  22.903  1.00 29.13  ? 130 VAL D CA  1 
ATOM   7826  C  C   . VAL D 1 130 ? 62.789  -0.233  23.772  1.00 28.92  ? 130 VAL D C   1 
ATOM   7827  O  O   . VAL D 1 130 ? 62.808  -0.333  24.970  1.00 25.64  ? 130 VAL D O   1 
ATOM   7828  C  CB  . VAL D 1 130 ? 61.304  -1.647  22.271  1.00 32.47  ? 130 VAL D CB  1 
ATOM   7829  C  CG1 . VAL D 1 130 ? 61.146  -2.948  21.497  1.00 31.22  ? 130 VAL D CG1 1 
ATOM   7830  C  CG2 . VAL D 1 130 ? 60.188  -1.580  23.300  1.00 32.70  ? 130 VAL D CG2 1 
ATOM   7831  N  N   . THR D 1 131 ? 62.743  0.940   23.137  1.00 31.18  ? 131 THR D N   1 
ATOM   7832  C  CA  . THR D 1 131 ? 62.786  2.207   23.842  1.00 36.95  ? 131 THR D CA  1 
ATOM   7833  C  C   . THR D 1 131 ? 61.585  3.006   23.366  1.00 32.14  ? 131 THR D C   1 
ATOM   7834  O  O   . THR D 1 131 ? 61.407  3.200   22.170  1.00 27.72  ? 131 THR D O   1 
ATOM   7835  C  CB  . THR D 1 131 ? 64.115  2.965   23.587  1.00 37.13  ? 131 THR D CB  1 
ATOM   7836  O  OG1 . THR D 1 131 ? 65.152  2.162   24.167  1.00 38.39  ? 131 THR D OG1 1 
ATOM   7837  C  CG2 . THR D 1 131 ? 64.100  4.422   24.069  1.00 29.21  ? 131 THR D CG2 1 
ATOM   7838  N  N   . PRO D 1 132 ? 60.733  3.521   24.282  1.00 32.94  ? 132 PRO D N   1 
ATOM   7839  C  CA  . PRO D 1 132 ? 59.502  4.189   23.867  1.00 29.48  ? 132 PRO D CA  1 
ATOM   7840  C  C   . PRO D 1 132 ? 59.898  5.515   23.288  1.00 27.97  ? 132 PRO D C   1 
ATOM   7841  O  O   . PRO D 1 132 ? 60.709  6.173   23.882  1.00 30.95  ? 132 PRO D O   1 
ATOM   7842  C  CB  . PRO D 1 132 ? 58.808  4.346   25.207  1.00 34.40  ? 132 PRO D CB  1 
ATOM   7843  C  CG  . PRO D 1 132 ? 59.353  3.196   25.983  1.00 34.48  ? 132 PRO D CG  1 
ATOM   7844  C  CD  . PRO D 1 132 ? 60.846  3.407   25.741  1.00 34.19  ? 132 PRO D CD  1 
ATOM   7845  N  N   . GLN D 1 133 ? 59.368  5.892   22.137  1.00 30.34  ? 133 GLN D N   1 
ATOM   7846  C  CA  . GLN D 1 133 ? 59.616  7.221   21.598  1.00 29.30  ? 133 GLN D CA  1 
ATOM   7847  C  C   . GLN D 1 133 ? 58.368  8.092   21.714  1.00 26.09  ? 133 GLN D C   1 
ATOM   7848  O  O   . GLN D 1 133 ? 58.490  9.279   21.749  1.00 27.93  ? 133 GLN D O   1 
ATOM   7849  C  CB  . GLN D 1 133 ? 59.862  7.192   20.087  1.00 40.22  ? 133 GLN D CB  1 
ATOM   7850  C  CG  . GLN D 1 133 ? 61.092  6.397   19.663  1.00 43.01  ? 133 GLN D CG  1 
ATOM   7851  C  CD  . GLN D 1 133 ? 62.342  7.054   20.196  1.00 42.04  ? 133 GLN D CD  1 
ATOM   7852  O  OE1 . GLN D 1 133 ? 62.476  8.282   20.095  1.00 43.10  ? 133 GLN D OE1 1 
ATOM   7853  N  NE2 . GLN D 1 133 ? 63.185  6.265   20.851  1.00 42.60  ? 133 GLN D NE2 1 
ATOM   7854  N  N   . ASP D 1 134 ? 57.166  7.532   21.631  1.00 24.00  ? 134 ASP D N   1 
ATOM   7855  C  CA  . ASP D 1 134 ? 55.961  8.358   21.629  1.00 27.56  ? 134 ASP D CA  1 
ATOM   7856  C  C   . ASP D 1 134 ? 54.807  7.501   22.105  1.00 22.71  ? 134 ASP D C   1 
ATOM   7857  O  O   . ASP D 1 134 ? 54.765  6.332   21.762  1.00 19.56  ? 134 ASP D O   1 
ATOM   7858  C  CB  . ASP D 1 134 ? 55.614  8.964   20.273  1.00 26.28  ? 134 ASP D CB  1 
ATOM   7859  C  CG  . ASP D 1 134 ? 54.752  10.220  20.365  1.00 27.28  ? 134 ASP D CG  1 
ATOM   7860  O  OD1 . ASP D 1 134 ? 54.712  10.785  21.454  1.00 22.98  ? 134 ASP D OD1 1 
ATOM   7861  O  OD2 . ASP D 1 134 ? 54.168  10.621  19.338  1.00 30.98  ? 134 ASP D OD2 1 
ATOM   7862  N  N   . GLU D 1 135 ? 54.018  8.078   23.012  1.00 22.02  ? 135 GLU D N   1 
ATOM   7863  C  CA  . GLU D 1 135 ? 52.851  7.418   23.536  1.00 22.66  ? 135 GLU D CA  1 
ATOM   7864  C  C   . GLU D 1 135 ? 51.751  8.460   23.605  1.00 19.53  ? 135 GLU D C   1 
ATOM   7865  O  O   . GLU D 1 135 ? 51.935  9.433   24.281  1.00 19.04  ? 135 GLU D O   1 
ATOM   7866  C  CB  . GLU D 1 135 ? 53.108  6.887   24.926  1.00 24.44  ? 135 GLU D CB  1 
ATOM   7867  C  CG  . GLU D 1 135 ? 51.900  6.087   25.410  1.00 31.61  ? 135 GLU D CG  1 
ATOM   7868  C  CD  . GLU D 1 135 ? 52.060  5.408   26.764  1.00 31.09  ? 135 GLU D CD  1 
ATOM   7869  O  OE1 . GLU D 1 135 ? 53.178  5.448   27.310  1.00 32.73  ? 135 GLU D OE1 1 
ATOM   7870  O  OE2 . GLU D 1 135 ? 51.047  4.873   27.258  1.00 30.04  ? 135 GLU D OE2 1 
ATOM   7871  N  N   . VAL D 1 136 ? 50.676  8.322   22.812  1.00 19.14  ? 136 VAL D N   1 
ATOM   7872  C  CA  . VAL D 1 136 ? 49.566  9.260   22.861  1.00 18.93  ? 136 VAL D CA  1 
ATOM   7873  C  C   . VAL D 1 136 ? 48.272  8.509   23.147  1.00 18.74  ? 136 VAL D C   1 
ATOM   7874  O  O   . VAL D 1 136 ? 47.995  7.445   22.548  1.00 21.10  ? 136 VAL D O   1 
ATOM   7875  C  CB  . VAL D 1 136 ? 49.485  10.016  21.542  1.00 22.38  ? 136 VAL D CB  1 
ATOM   7876  C  CG1 . VAL D 1 136 ? 48.288  10.903  21.474  1.00 25.53  ? 136 VAL D CG1 1 
ATOM   7877  C  CG2 . VAL D 1 136 ? 50.694  10.879  21.319  1.00 29.20  ? 136 VAL D CG2 1 
ATOM   7878  N  N   . HIS D 1 137 ? 47.511  9.088   24.089  1.00 19.69  ? 137 HIS D N   1 
ATOM   7879  C  CA  . HIS D 1 137 ? 46.174  8.633   24.397  1.00 21.58  ? 137 HIS D CA  1 
ATOM   7880  C  C   . HIS D 1 137 ? 45.150  9.593   23.779  1.00 23.10  ? 137 HIS D C   1 
ATOM   7881  O  O   . HIS D 1 137 ? 45.040  10.764  24.188  1.00 22.31  ? 137 HIS D O   1 
ATOM   7882  C  CB  . HIS D 1 137 ? 45.971  8.459   25.905  1.00 24.80  ? 137 HIS D CB  1 
ATOM   7883  C  CG  . HIS D 1 137 ? 46.859  7.471   26.553  1.00 23.98  ? 137 HIS D CG  1 
ATOM   7884  N  ND1 . HIS D 1 137 ? 46.744  7.266   27.889  1.00 25.96  ? 137 HIS D ND1 1 
ATOM   7885  C  CD2 . HIS D 1 137 ? 47.982  6.870   26.153  1.00 27.18  ? 137 HIS D CD2 1 
ATOM   7886  C  CE1 . HIS D 1 137 ? 47.744  6.470   28.246  1.00 32.08  ? 137 HIS D CE1 1 
ATOM   7887  N  NE2 . HIS D 1 137 ? 48.502  6.200   27.192  1.00 29.00  ? 137 HIS D NE2 1 
ATOM   7888  N  N   . GLY D 1 138 ? 44.448  9.080   22.762  1.00 24.48  ? 138 GLY D N   1 
ATOM   7889  C  CA  . GLY D 1 138 ? 43.532  9.899   21.995  1.00 24.41  ? 138 GLY D CA  1 
ATOM   7890  C  C   . GLY D 1 138 ? 42.087  9.632   22.403  1.00 23.09  ? 138 GLY D C   1 
ATOM   7891  O  O   . GLY D 1 138 ? 41.756  8.512   22.709  1.00 19.31  ? 138 GLY D O   1 
ATOM   7892  N  N   . PHE D 1 139 ? 41.237  10.658  22.272  1.00 21.98  ? 139 PHE D N   1 
ATOM   7893  C  CA  . PHE D 1 139 ? 39.806  10.560  22.514  1.00 24.95  ? 139 PHE D CA  1 
ATOM   7894  C  C   . PHE D 1 139 ? 39.045  11.327  21.428  1.00 28.68  ? 139 PHE D C   1 
ATOM   7895  O  O   . PHE D 1 139 ? 39.453  12.429  21.063  1.00 31.92  ? 139 PHE D O   1 
ATOM   7896  C  CB  . PHE D 1 139 ? 39.579  11.118  23.925  1.00 23.64  ? 139 PHE D CB  1 
ATOM   7897  C  CG  . PHE D 1 139 ? 40.170  12.473  24.223  1.00 23.25  ? 139 PHE D CG  1 
ATOM   7898  C  CD1 . PHE D 1 139 ? 39.517  13.643  23.867  1.00 23.30  ? 139 PHE D CD1 1 
ATOM   7899  C  CD2 . PHE D 1 139 ? 41.380  12.560  24.903  1.00 27.51  ? 139 PHE D CD2 1 
ATOM   7900  C  CE1 . PHE D 1 139 ? 40.099  14.893  24.123  1.00 28.87  ? 139 PHE D CE1 1 
ATOM   7901  C  CE2 . PHE D 1 139 ? 41.946  13.811  25.187  1.00 30.59  ? 139 PHE D CE2 1 
ATOM   7902  C  CZ  . PHE D 1 139 ? 41.308  14.981  24.784  1.00 28.87  ? 139 PHE D CZ  1 
ATOM   7903  N  N   . LYS D 1 140 ? 37.938  10.782  20.929  1.00 29.43  ? 140 LYS D N   1 
ATOM   7904  C  CA  . LYS D 1 140 ? 37.111  11.497  19.955  1.00 36.35  ? 140 LYS D CA  1 
ATOM   7905  C  C   . LYS D 1 140 ? 36.224  12.465  20.724  1.00 27.47  ? 140 LYS D C   1 
ATOM   7906  O  O   . LYS D 1 140 ? 35.805  12.135  21.801  1.00 22.13  ? 140 LYS D O   1 
ATOM   7907  C  CB  . LYS D 1 140 ? 36.406  10.511  19.013  1.00 55.00  ? 140 LYS D CB  1 
ATOM   7908  C  CG  . LYS D 1 140 ? 36.336  10.954  17.499  1.00 81.72  ? 140 LYS D CG  1 
ATOM   7909  C  CD  . LYS D 1 140 ? 37.568  11.212  16.608  1.00 88.33  ? 140 LYS D CD  1 
ATOM   7910  C  CE  . LYS D 1 140 ? 37.504  12.437  15.628  1.00 89.30  ? 140 LYS D CE  1 
ATOM   7911  N  NZ  . LYS D 1 140 ? 37.602  12.142  14.187  1.00 80.95  ? 140 LYS D NZ  1 
ATOM   7912  N  N   . TYR D 1 141 ? 36.067  13.707  20.262  1.00 31.68  ? 141 TYR D N   1 
ATOM   7913  C  CA  . TYR D 1 141 ? 34.978  14.560  20.713  1.00 35.44  ? 141 TYR D CA  1 
ATOM   7914  C  C   . TYR D 1 141 ? 33.628  14.107  20.159  1.00 49.38  ? 141 TYR D C   1 
ATOM   7915  O  O   . TYR D 1 141 ? 33.559  13.245  19.297  1.00 64.42  ? 141 TYR D O   1 
ATOM   7916  C  CB  . TYR D 1 141 ? 35.159  15.979  20.244  1.00 41.36  ? 141 TYR D CB  1 
ATOM   7917  C  CG  . TYR D 1 141 ? 36.122  16.766  21.107  1.00 37.22  ? 141 TYR D CG  1 
ATOM   7918  C  CD1 . TYR D 1 141 ? 35.720  17.345  22.276  1.00 40.93  ? 141 TYR D CD1 1 
ATOM   7919  C  CD2 . TYR D 1 141 ? 37.379  16.986  20.686  1.00 43.52  ? 141 TYR D CD2 1 
ATOM   7920  C  CE1 . TYR D 1 141 ? 36.557  18.134  23.018  1.00 39.81  ? 141 TYR D CE1 1 
ATOM   7921  C  CE2 . TYR D 1 141 ? 38.249  17.728  21.435  1.00 53.41  ? 141 TYR D CE2 1 
ATOM   7922  C  CZ  . TYR D 1 141 ? 37.841  18.296  22.608  1.00 48.05  ? 141 TYR D CZ  1 
ATOM   7923  O  OH  . TYR D 1 141 ? 38.787  18.986  23.294  1.00 57.12  ? 141 TYR D OH  1 
ATOM   7924  N  N   . PHE D 1 142 ? 32.529  14.577  20.737  1.00 59.78  ? 142 PHE D N   1 
ATOM   7925  C  CA  . PHE D 1 142 ? 31.380  13.686  20.756  1.00 71.39  ? 142 PHE D CA  1 
ATOM   7926  C  C   . PHE D 1 142 ? 30.672  13.788  19.394  1.00 60.75  ? 142 PHE D C   1 
ATOM   7927  O  O   . PHE D 1 142 ? 29.897  12.868  19.116  1.00 78.25  ? 142 PHE D O   1 
ATOM   7928  C  CB  . PHE D 1 142 ? 30.499  13.729  22.034  1.00 88.45  ? 142 PHE D CB  1 
ATOM   7929  C  CG  . PHE D 1 142 ? 29.539  14.900  22.104  1.00 79.11  ? 142 PHE D CG  1 
ATOM   7930  C  CD1 . PHE D 1 142 ? 30.002  16.138  22.583  1.00 82.02  ? 142 PHE D CD1 1 
ATOM   7931  C  CD2 . PHE D 1 142 ? 28.247  14.787  21.568  1.00 58.90  ? 142 PHE D CD2 1 
ATOM   7932  C  CE1 . PHE D 1 142 ? 29.160  17.249  22.580  1.00 98.15  ? 142 PHE D CE1 1 
ATOM   7933  C  CE2 . PHE D 1 142 ? 27.401  15.898  21.573  1.00 84.58  ? 142 PHE D CE2 1 
ATOM   7934  C  CZ  . PHE D 1 142 ? 27.853  17.128  22.076  1.00 101.37 ? 142 PHE D CZ  1 
ATOM   7935  N  N   . ASP D 1 143 ? 30.964  14.763  18.507  1.00 35.20  ? 143 ASP D N   1 
ATOM   7936  C  CA  . ASP D 1 143 ? 30.348  14.635  17.181  1.00 39.50  ? 143 ASP D CA  1 
ATOM   7937  C  C   . ASP D 1 143 ? 31.386  14.462  16.097  1.00 37.83  ? 143 ASP D C   1 
ATOM   7938  O  O   . ASP D 1 143 ? 31.325  15.116  15.067  1.00 38.09  ? 143 ASP D O   1 
ATOM   7939  C  CB  . ASP D 1 143 ? 29.486  15.815  16.757  1.00 58.01  ? 143 ASP D CB  1 
ATOM   7940  C  CG  . ASP D 1 143 ? 29.831  17.086  17.514  1.00 73.45  ? 143 ASP D CG  1 
ATOM   7941  O  OD1 . ASP D 1 143 ? 30.733  17.032  18.456  1.00 60.05  ? 143 ASP D OD1 1 
ATOM   7942  O  OD2 . ASP D 1 143 ? 29.178  18.087  17.150  1.00 75.64  ? 143 ASP D OD2 1 
ATOM   7943  N  N   . GLU D 1 144 ? 32.315  13.540  16.322  1.00 30.22  ? 144 GLU D N   1 
ATOM   7944  C  CA  . GLU D 1 144 ? 33.489  13.335  15.494  1.00 26.00  ? 144 GLU D CA  1 
ATOM   7945  C  C   . GLU D 1 144 ? 34.283  14.608  15.184  1.00 21.65  ? 144 GLU D C   1 
ATOM   7946  O  O   . GLU D 1 144 ? 35.026  14.627  14.223  1.00 24.22  ? 144 GLU D O   1 
ATOM   7947  C  CB  . GLU D 1 144 ? 33.044  12.568  14.260  1.00 32.06  ? 144 GLU D CB  1 
ATOM   7948  C  CG  . GLU D 1 144 ? 32.342  11.254  14.592  1.00 34.40  ? 144 GLU D CG  1 
ATOM   7949  C  CD  . GLU D 1 144 ? 33.305  10.221  15.139  1.00 39.78  ? 144 GLU D CD  1 
ATOM   7950  O  OE1 . GLU D 1 144 ? 34.465  10.195  14.672  1.00 34.65  ? 144 GLU D OE1 1 
ATOM   7951  O  OE2 . GLU D 1 144 ? 32.861  9.422   15.995  1.00 45.40  ? 144 GLU D OE2 1 
ATOM   7952  N  N   . ARG D 1 145 ? 34.233  15.602  16.069  1.00 23.14  ? 145 ARG D N   1 
ATOM   7953  C  CA  . ARG D 1 145 ? 35.013  16.822  15.950  1.00 24.21  ? 145 ARG D CA  1 
ATOM   7954  C  C   . ARG D 1 145 ? 36.450  16.634  16.440  1.00 26.64  ? 145 ARG D C   1 
ATOM   7955  O  O   . ARG D 1 145 ? 36.774  15.747  17.275  1.00 25.30  ? 145 ARG D O   1 
ATOM   7956  C  CB  . ARG D 1 145 ? 34.299  17.994  16.644  1.00 23.80  ? 145 ARG D CB  1 
ATOM   7957  C  CG  . ARG D 1 145 ? 33.067  18.301  15.809  1.00 25.68  ? 145 ARG D CG  1 
ATOM   7958  C  CD  . ARG D 1 145 ? 32.373  19.523  16.284  1.00 25.70  ? 145 ARG D CD  1 
ATOM   7959  N  NE  . ARG D 1 145 ? 31.052  19.759  15.688  1.00 27.92  ? 145 ARG D NE  1 
ATOM   7960  C  CZ  . ARG D 1 145 ? 30.784  20.350  14.549  1.00 28.09  ? 145 ARG D CZ  1 
ATOM   7961  N  NH1 . ARG D 1 145 ? 31.692  21.063  13.917  1.00 25.89  ? 145 ARG D NH1 1 
ATOM   7962  N  NH2 . ARG D 1 145 ? 29.581  20.228  14.034  1.00 30.10  ? 145 ARG D NH2 1 
ATOM   7963  N  N   . ASP D 1 146 ? 37.316  17.467  15.832  1.00 23.71  ? 146 ASP D N   1 
ATOM   7964  C  CA  . ASP D 1 146 ? 38.699  17.539  16.263  1.00 26.18  ? 146 ASP D CA  1 
ATOM   7965  C  C   . ASP D 1 146 ? 38.844  18.735  17.183  1.00 22.41  ? 146 ASP D C   1 
ATOM   7966  O  O   . ASP D 1 146 ? 37.911  19.435  17.512  1.00 23.87  ? 146 ASP D O   1 
ATOM   7967  C  CB  . ASP D 1 146 ? 39.649  17.466  15.076  1.00 26.61  ? 146 ASP D CB  1 
ATOM   7968  C  CG  . ASP D 1 146 ? 39.493  18.618  14.070  1.00 28.59  ? 146 ASP D CG  1 
ATOM   7969  O  OD1 . ASP D 1 146 ? 39.040  19.689  14.499  1.00 25.17  ? 146 ASP D OD1 1 
ATOM   7970  O  OD2 . ASP D 1 146 ? 39.746  18.429  12.841  1.00 30.75  ? 146 ASP D OD2 1 
ATOM   7971  N  N   . MET D 1 147 ? 40.080  18.963  17.553  1.00 26.31  ? 147 MET D N   1 
ATOM   7972  C  CA  . MET D 1 147 ? 40.478  20.014  18.481  1.00 26.20  ? 147 MET D CA  1 
ATOM   7973  C  C   . MET D 1 147 ? 40.275  21.387  17.860  1.00 22.77  ? 147 MET D C   1 
ATOM   7974  O  O   . MET D 1 147 ? 40.187  22.334  18.570  1.00 19.69  ? 147 MET D O   1 
ATOM   7975  C  CB  . MET D 1 147 ? 41.961  19.743  18.782  1.00 34.33  ? 147 MET D CB  1 
ATOM   7976  C  CG  . MET D 1 147 ? 42.460  20.248  20.063  1.00 37.31  ? 147 MET D CG  1 
ATOM   7977  S  SD  . MET D 1 147 ? 41.529  19.670  21.467  1.00 33.94  ? 147 MET D SD  1 
ATOM   7978  C  CE  . MET D 1 147 ? 42.500  18.321  22.111  1.00 44.54  ? 147 MET D CE  1 
ATOM   7979  N  N   . LEU D 1 148 ? 40.236  21.551  16.538  1.00 20.79  ? 148 LEU D N   1 
ATOM   7980  C  CA  . LEU D 1 148 ? 39.908  22.845  15.967  1.00 22.76  ? 148 LEU D CA  1 
ATOM   7981  C  C   . LEU D 1 148 ? 38.383  23.054  15.861  1.00 21.99  ? 148 LEU D C   1 
ATOM   7982  O  O   . LEU D 1 148 ? 37.922  24.075  15.340  1.00 19.95  ? 148 LEU D O   1 
ATOM   7983  C  CB  . LEU D 1 148 ? 40.538  22.862  14.582  1.00 21.62  ? 148 LEU D CB  1 
ATOM   7984  C  CG  . LEU D 1 148 ? 42.052  22.747  14.488  1.00 21.47  ? 148 LEU D CG  1 
ATOM   7985  C  CD1 . LEU D 1 148 ? 42.451  22.878  13.013  1.00 22.68  ? 148 LEU D CD1 1 
ATOM   7986  C  CD2 . LEU D 1 148 ? 42.729  23.823  15.271  1.00 22.35  ? 148 LEU D CD2 1 
ATOM   7987  N  N   . GLY D 1 149 ? 37.590  22.062  16.262  1.00 20.01  ? 149 GLY D N   1 
ATOM   7988  C  CA  . GLY D 1 149 ? 36.157  22.228  16.288  1.00 21.04  ? 149 GLY D CA  1 
ATOM   7989  C  C   . GLY D 1 149 ? 35.435  21.794  15.011  1.00 23.95  ? 149 GLY D C   1 
ATOM   7990  O  O   . GLY D 1 149 ? 34.234  22.071  14.897  1.00 23.30  ? 149 GLY D O   1 
ATOM   7991  N  N   . PHE D 1 150 ? 36.148  21.199  14.035  1.00 23.08  ? 150 PHE D N   1 
ATOM   7992  C  CA  . PHE D 1 150 ? 35.565  20.760  12.775  1.00 19.76  ? 150 PHE D CA  1 
ATOM   7993  C  C   . PHE D 1 150 ? 35.348  19.258  12.803  1.00 20.27  ? 150 PHE D C   1 
ATOM   7994  O  O   . PHE D 1 150 ? 36.115  18.519  13.428  1.00 21.27  ? 150 PHE D O   1 
ATOM   7995  C  CB  . PHE D 1 150 ? 36.486  21.129  11.610  1.00 20.10  ? 150 PHE D CB  1 
ATOM   7996  C  CG  . PHE D 1 150 ? 36.275  22.581  11.200  1.00 17.91  ? 150 PHE D CG  1 
ATOM   7997  C  CD1 . PHE D 1 150 ? 36.750  23.597  11.985  1.00 16.44  ? 150 PHE D CD1 1 
ATOM   7998  C  CD2 . PHE D 1 150 ? 35.606  22.913  10.031  1.00 16.84  ? 150 PHE D CD2 1 
ATOM   7999  C  CE1 . PHE D 1 150 ? 36.553  24.912  11.598  1.00 18.19  ? 150 PHE D CE1 1 
ATOM   8000  C  CE2 . PHE D 1 150 ? 35.435  24.228  9.660   1.00 15.87  ? 150 PHE D CE2 1 
ATOM   8001  C  CZ  . PHE D 1 150 ? 35.896  25.220  10.438  1.00 16.96  ? 150 PHE D CZ  1 
ATOM   8002  N  N   . VAL D 1 151 ? 34.317  18.813  12.073  1.00 22.10  ? 151 VAL D N   1 
ATOM   8003  C  CA  . VAL D 1 151 ? 34.095  17.392  11.891  1.00 24.33  ? 151 VAL D CA  1 
ATOM   8004  C  C   . VAL D 1 151 ? 35.254  16.852  11.041  1.00 26.50  ? 151 VAL D C   1 
ATOM   8005  O  O   . VAL D 1 151 ? 35.613  17.446  10.023  1.00 26.79  ? 151 VAL D O   1 
ATOM   8006  C  CB  . VAL D 1 151 ? 32.763  17.075  11.217  1.00 23.81  ? 151 VAL D CB  1 
ATOM   8007  C  CG1 . VAL D 1 151 ? 32.583  15.564  11.110  1.00 23.61  ? 151 VAL D CG1 1 
ATOM   8008  C  CG2 . VAL D 1 151 ? 31.617  17.793  11.922  1.00 28.26  ? 151 VAL D CG2 1 
ATOM   8009  N  N   . ASP D 1 152 ? 35.788  15.680  11.454  1.00 24.48  ? 152 ASP D N   1 
ATOM   8010  C  CA  . ASP D 1 152 ? 37.052  15.195  10.965  1.00 25.76  ? 152 ASP D CA  1 
ATOM   8011  C  C   . ASP D 1 152 ? 36.803  13.745  10.608  1.00 24.00  ? 152 ASP D C   1 
ATOM   8012  O  O   . ASP D 1 152 ? 36.584  12.956  11.505  1.00 29.69  ? 152 ASP D O   1 
ATOM   8013  C  CB  . ASP D 1 152 ? 38.151  15.401  12.022  1.00 31.89  ? 152 ASP D CB  1 
ATOM   8014  C  CG  . ASP D 1 152 ? 39.625  15.173  11.633  1.00 36.67  ? 152 ASP D CG  1 
ATOM   8015  O  OD1 . ASP D 1 152 ? 39.882  14.140  10.917  1.00 31.80  ? 152 ASP D OD1 1 
ATOM   8016  O  OD2 . ASP D 1 152 ? 40.541  15.959  12.137  1.00 29.71  ? 152 ASP D OD2 1 
ATOM   8017  N  N   . GLY D 1 153 ? 36.875  13.424  9.317   1.00 23.00  ? 153 GLY D N   1 
ATOM   8018  C  CA  . GLY D 1 153 ? 36.716  12.079  8.815   1.00 21.23  ? 153 GLY D CA  1 
ATOM   8019  C  C   . GLY D 1 153 ? 35.676  11.925  7.708   1.00 24.00  ? 153 GLY D C   1 
ATOM   8020  O  O   . GLY D 1 153 ? 35.600  10.861  7.089   1.00 27.27  ? 153 GLY D O   1 
ATOM   8021  N  N   . THR D 1 154 ? 34.944  13.012  7.385   1.00 24.88  ? 154 THR D N   1 
ATOM   8022  C  CA  . THR D 1 154 ? 33.755  13.005  6.563   1.00 19.98  ? 154 THR D CA  1 
ATOM   8023  C  C   . THR D 1 154 ? 34.018  12.397  5.208   1.00 20.08  ? 154 THR D C   1 
ATOM   8024  O  O   . THR D 1 154 ? 33.274  11.556  4.740   1.00 20.18  ? 154 THR D O   1 
ATOM   8025  C  CB  . THR D 1 154 ? 33.298  14.436  6.435   1.00 21.82  ? 154 THR D CB  1 
ATOM   8026  O  OG1 . THR D 1 154 ? 33.142  14.950  7.747   1.00 21.91  ? 154 THR D OG1 1 
ATOM   8027  C  CG2 . THR D 1 154 ? 31.995  14.536  5.675   1.00 24.69  ? 154 THR D CG2 1 
ATOM   8028  N  N   . GLU D 1 155 ? 35.109  12.803  4.580   1.00 20.77  ? 155 GLU D N   1 
ATOM   8029  C  CA  . GLU D 1 155 ? 35.356  12.368  3.214   1.00 25.62  ? 155 GLU D CA  1 
ATOM   8030  C  C   . GLU D 1 155 ? 36.224  11.107  3.119   1.00 25.21  ? 155 GLU D C   1 
ATOM   8031  O  O   . GLU D 1 155 ? 36.733  10.769  2.067   1.00 26.27  ? 155 GLU D O   1 
ATOM   8032  C  CB  . GLU D 1 155 ? 35.955  13.508  2.387   1.00 27.33  ? 155 GLU D CB  1 
ATOM   8033  C  CG  . GLU D 1 155 ? 34.871  14.527  2.029   1.00 33.33  ? 155 GLU D CG  1 
ATOM   8034  C  CD  . GLU D 1 155 ? 33.689  14.090  1.162   1.00 33.54  ? 155 GLU D CD  1 
ATOM   8035  O  OE1 . GLU D 1 155 ? 33.940  13.487  0.148   1.00 35.99  ? 155 GLU D OE1 1 
ATOM   8036  O  OE2 . GLU D 1 155 ? 32.529  14.404  1.413   1.00 38.93  ? 155 GLU D OE2 1 
ATOM   8037  N  N   . ASN D 1 156 ? 36.429  10.393  4.209   1.00 25.94  ? 156 ASN D N   1 
ATOM   8038  C  CA  . ASN D 1 156 ? 37.157  9.155   4.094   1.00 24.16  ? 156 ASN D CA  1 
ATOM   8039  C  C   . ASN D 1 156 ? 36.437  8.209   3.149   1.00 25.56  ? 156 ASN D C   1 
ATOM   8040  O  O   . ASN D 1 156 ? 35.224  8.094   3.223   1.00 27.88  ? 156 ASN D O   1 
ATOM   8041  C  CB  . ASN D 1 156 ? 37.234  8.429   5.419   1.00 23.70  ? 156 ASN D CB  1 
ATOM   8042  C  CG  . ASN D 1 156 ? 38.476  8.745   6.181   1.00 22.03  ? 156 ASN D CG  1 
ATOM   8043  O  OD1 . ASN D 1 156 ? 39.522  9.054   5.614   1.00 27.16  ? 156 ASN D OD1 1 
ATOM   8044  N  ND2 . ASN D 1 156 ? 38.336  8.712   7.471   1.00 19.93  ? 156 ASN D ND2 1 
ATOM   8045  N  N   . PRO D 1 157 ? 37.146  7.401   2.358   1.00 25.32  ? 157 PRO D N   1 
ATOM   8046  C  CA  . PRO D 1 157 ? 36.469  6.383   1.563   1.00 27.70  ? 157 PRO D CA  1 
ATOM   8047  C  C   . PRO D 1 157 ? 35.851  5.313   2.457   1.00 29.58  ? 157 PRO D C   1 
ATOM   8048  O  O   . PRO D 1 157 ? 36.295  5.122   3.571   1.00 32.28  ? 157 PRO D O   1 
ATOM   8049  C  CB  . PRO D 1 157 ? 37.610  5.907   0.660   1.00 24.14  ? 157 PRO D CB  1 
ATOM   8050  C  CG  . PRO D 1 157 ? 38.801  6.036   1.518   1.00 26.63  ? 157 PRO D CG  1 
ATOM   8051  C  CD  . PRO D 1 157 ? 38.603  7.358   2.238   1.00 27.21  ? 157 PRO D CD  1 
ATOM   8052  N  N   . THR D 1 158 ? 34.832  4.611   1.950   1.00 38.02  ? 158 THR D N   1 
ATOM   8053  C  CA  . THR D 1 158 ? 34.258  3.442   2.630   1.00 39.48  ? 158 THR D CA  1 
ATOM   8054  C  C   . THR D 1 158 ? 34.093  2.262   1.653   1.00 38.47  ? 158 THR D C   1 
ATOM   8055  O  O   . THR D 1 158 ? 34.157  2.388   0.416   1.00 35.94  ? 158 THR D O   1 
ATOM   8056  C  CB  . THR D 1 158 ? 32.923  3.792   3.306   1.00 41.37  ? 158 THR D CB  1 
ATOM   8057  O  OG1 . THR D 1 158 ? 32.088  4.085   2.186   1.00 37.52  ? 158 THR D OG1 1 
ATOM   8058  C  CG2 . THR D 1 158 ? 33.020  4.921   4.329   1.00 39.37  ? 158 THR D CG2 1 
ATOM   8059  N  N   . GLY D 1 159 ? 33.890  1.077   2.234   1.00 38.78  ? 159 GLY D N   1 
ATOM   8060  C  CA  . GLY D 1 159 ? 33.584  -0.096  1.422   1.00 37.52  ? 159 GLY D CA  1 
ATOM   8061  C  C   . GLY D 1 159 ? 34.712  -0.422  0.451   1.00 34.57  ? 159 GLY D C   1 
ATOM   8062  O  O   . GLY D 1 159 ? 35.869  -0.450  0.824   1.00 34.35  ? 159 GLY D O   1 
ATOM   8063  N  N   . ALA D 1 160 ? 34.362  -0.678  -0.798  1.00 34.65  ? 160 ALA D N   1 
ATOM   8064  C  CA  . ALA D 1 160 ? 35.307  -1.210  -1.771  1.00 37.50  ? 160 ALA D CA  1 
ATOM   8065  C  C   . ALA D 1 160 ? 36.223  -0.087  -2.182  1.00 37.80  ? 160 ALA D C   1 
ATOM   8066  O  O   . ALA D 1 160 ? 37.342  -0.347  -2.548  1.00 41.13  ? 160 ALA D O   1 
ATOM   8067  C  CB  . ALA D 1 160 ? 34.658  -1.802  -3.036  1.00 35.69  ? 160 ALA D CB  1 
ATOM   8068  N  N   . ALA D 1 161 ? 35.742  1.150   -2.143  1.00 42.32  ? 161 ALA D N   1 
ATOM   8069  C  CA  . ALA D 1 161 ? 36.612  2.284   -2.450  1.00 46.02  ? 161 ALA D CA  1 
ATOM   8070  C  C   . ALA D 1 161 ? 37.772  2.362   -1.430  1.00 43.75  ? 161 ALA D C   1 
ATOM   8071  O  O   . ALA D 1 161 ? 38.918  2.676   -1.790  1.00 37.78  ? 161 ALA D O   1 
ATOM   8072  C  CB  . ALA D 1 161 ? 35.827  3.597   -2.490  1.00 36.18  ? 161 ALA D CB  1 
ATOM   8073  N  N   . ALA D 1 162 ? 37.438  2.068   -0.161  1.00 30.67  ? 162 ALA D N   1 
ATOM   8074  C  CA  . ALA D 1 162 ? 38.440  2.051   0.874   1.00 36.99  ? 162 ALA D CA  1 
ATOM   8075  C  C   . ALA D 1 162 ? 39.456  0.909   0.681   1.00 35.75  ? 162 ALA D C   1 
ATOM   8076  O  O   . ALA D 1 162 ? 40.660  1.177   0.701   1.00 38.43  ? 162 ALA D O   1 
ATOM   8077  C  CB  . ALA D 1 162 ? 37.786  2.062   2.235   1.00 35.88  ? 162 ALA D CB  1 
ATOM   8078  N  N   . ARG D 1 163 ? 39.002  -0.329  0.450   1.00 31.24  ? 163 ARG D N   1 
ATOM   8079  C  CA  . ARG D 1 163 ? 39.887  -1.434  0.169   1.00 31.05  ? 163 ARG D CA  1 
ATOM   8080  C  C   . ARG D 1 163 ? 40.812  -1.045  -0.986  1.00 29.76  ? 163 ARG D C   1 
ATOM   8081  O  O   . ARG D 1 163 ? 42.017  -1.204  -0.836  1.00 36.05  ? 163 ARG D O   1 
ATOM   8082  C  CB  . ARG D 1 163 ? 39.148  -2.764  -0.064  1.00 39.86  ? 163 ARG D CB  1 
ATOM   8083  C  CG  . ARG D 1 163 ? 38.072  -3.251  0.913   1.00 55.56  ? 163 ARG D CG  1 
ATOM   8084  C  CD  . ARG D 1 163 ? 38.351  -4.450  1.824   1.00 65.50  ? 163 ARG D CD  1 
ATOM   8085  N  NE  . ARG D 1 163 ? 38.446  -5.710  1.088   1.00 67.62  ? 163 ARG D NE  1 
ATOM   8086  N  N   . ARG D 1 164 ? 40.301  -0.465  -2.080  1.00 27.51  ? 164 ARG D N   1 
ATOM   8087  C  CA  . ARG D 1 164 ? 41.092  -0.144  -3.270  1.00 29.50  ? 164 ARG D CA  1 
ATOM   8088  C  C   . ARG D 1 164 ? 42.127  0.932   -2.902  1.00 29.80  ? 164 ARG D C   1 
ATOM   8089  O  O   . ARG D 1 164 ? 43.207  0.996   -3.474  1.00 31.14  ? 164 ARG D O   1 
ATOM   8090  C  CB  . ARG D 1 164 ? 40.228  0.162   -4.540  1.00 35.81  ? 164 ARG D CB  1 
ATOM   8091  C  CG  . ARG D 1 164 ? 40.607  0.895   -5.854  1.00 36.41  ? 164 ARG D CG  1 
ATOM   8092  N  N   . ALA D 1 165 ? 41.818  1.818   -1.957  1.00 27.02  ? 165 ALA D N   1 
ATOM   8093  C  CA  . ALA D 1 165 ? 42.703  2.938   -1.691  1.00 28.39  ? 165 ALA D CA  1 
ATOM   8094  C  C   . ALA D 1 165 ? 43.843  2.564   -0.742  1.00 26.56  ? 165 ALA D C   1 
ATOM   8095  O  O   . ALA D 1 165 ? 44.919  3.210   -0.783  1.00 28.49  ? 165 ALA D O   1 
ATOM   8096  C  CB  . ALA D 1 165 ? 41.876  4.112   -1.151  1.00 27.66  ? 165 ALA D CB  1 
ATOM   8097  N  N   . VAL D 1 166 ? 43.586  1.586   0.147   1.00 25.10  ? 166 VAL D N   1 
ATOM   8098  C  CA  . VAL D 1 166 ? 44.491  1.381   1.259   1.00 27.16  ? 166 VAL D CA  1 
ATOM   8099  C  C   . VAL D 1 166 ? 45.310  0.075   1.194   1.00 27.37  ? 166 VAL D C   1 
ATOM   8100  O  O   . VAL D 1 166 ? 46.395  0.046   1.724   1.00 24.29  ? 166 VAL D O   1 
ATOM   8101  C  CB  . VAL D 1 166 ? 43.843  1.571   2.637   1.00 27.86  ? 166 VAL D CB  1 
ATOM   8102  C  CG1 . VAL D 1 166 ? 42.763  2.631   2.668   1.00 28.48  ? 166 VAL D CG1 1 
ATOM   8103  C  CG2 . VAL D 1 166 ? 43.346  0.283   3.189   1.00 29.30  ? 166 VAL D CG2 1 
ATOM   8104  N  N   . LEU D 1 167 ? 44.874  -0.963  0.498   1.00 27.61  ? 167 LEU D N   1 
ATOM   8105  C  CA  . LEU D 1 167 ? 45.515  -2.274  0.541   1.00 29.50  ? 167 LEU D CA  1 
ATOM   8106  C  C   . LEU D 1 167 ? 46.376  -2.511  -0.698  1.00 30.46  ? 167 LEU D C   1 
ATOM   8107  O  O   . LEU D 1 167 ? 45.991  -2.240  -1.849  1.00 26.58  ? 167 LEU D O   1 
ATOM   8108  C  CB  . LEU D 1 167 ? 44.463  -3.383  0.682   1.00 30.21  ? 167 LEU D CB  1 
ATOM   8109  C  CG  . LEU D 1 167 ? 43.599  -3.277  1.936   1.00 33.35  ? 167 LEU D CG  1 
ATOM   8110  C  CD1 . LEU D 1 167 ? 42.548  -4.319  2.025   1.00 34.75  ? 167 LEU D CD1 1 
ATOM   8111  C  CD2 . LEU D 1 167 ? 44.457  -3.245  3.213   1.00 38.88  ? 167 LEU D CD2 1 
ATOM   8112  N  N   . VAL D 1 168 ? 47.583  -3.008  -0.420  1.00 29.62  ? 168 VAL D N   1 
ATOM   8113  C  CA  . VAL D 1 168 ? 48.488  -3.399  -1.470  1.00 33.35  ? 168 VAL D CA  1 
ATOM   8114  C  C   . VAL D 1 168 ? 47.827  -4.537  -2.255  1.00 30.61  ? 168 VAL D C   1 
ATOM   8115  O  O   . VAL D 1 168 ? 47.249  -5.460  -1.670  1.00 26.30  ? 168 VAL D O   1 
ATOM   8116  C  CB  . VAL D 1 168 ? 49.838  -3.818  -0.856  1.00 29.91  ? 168 VAL D CB  1 
ATOM   8117  C  CG1 . VAL D 1 168 ? 50.729  -4.453  -1.914  1.00 26.51  ? 168 VAL D CG1 1 
ATOM   8118  C  CG2 . VAL D 1 168 ? 50.537  -2.632  -0.191  1.00 28.87  ? 168 VAL D CG2 1 
ATOM   8119  N  N   . GLY D 1 169 ? 47.944  -4.479  -3.580  1.00 34.88  ? 169 GLY D N   1 
ATOM   8120  C  CA  . GLY D 1 169 ? 47.443  -5.576  -4.414  1.00 37.38  ? 169 GLY D CA  1 
ATOM   8121  C  C   . GLY D 1 169 ? 48.546  -6.154  -5.301  1.00 41.02  ? 169 GLY D C   1 
ATOM   8122  O  O   . GLY D 1 169 ? 49.714  -6.350  -4.888  1.00 43.34  ? 169 GLY D O   1 
ATOM   8123  N  N   . ALA D 1 170 ? 48.155  -6.420  -6.554  1.00 43.52  ? 170 ALA D N   1 
ATOM   8124  C  CA  . ALA D 1 170 ? 49.006  -7.153  -7.467  1.00 35.47  ? 170 ALA D CA  1 
ATOM   8125  C  C   . ALA D 1 170 ? 50.187  -6.305  -7.947  1.00 36.09  ? 170 ALA D C   1 
ATOM   8126  O  O   . ALA D 1 170 ? 51.152  -6.868  -8.448  1.00 39.41  ? 170 ALA D O   1 
ATOM   8127  C  CB  . ALA D 1 170 ? 48.188  -7.703  -8.579  1.00 34.16  ? 170 ALA D CB  1 
ATOM   8128  N  N   . GLU D 1 171 ? 50.238  -5.003  -7.645  1.00 29.94  ? 171 GLU D N   1 
ATOM   8129  C  CA  . GLU D 1 171 ? 51.436  -4.229  -7.930  1.00 30.51  ? 171 GLU D CA  1 
ATOM   8130  C  C   . GLU D 1 171 ? 52.633  -4.654  -7.070  1.00 35.00  ? 171 GLU D C   1 
ATOM   8131  O  O   . GLU D 1 171 ? 53.751  -4.213  -7.345  1.00 36.62  ? 171 GLU D O   1 
ATOM   8132  C  CB  . GLU D 1 171 ? 51.208  -2.711  -7.829  1.00 31.13  ? 171 GLU D CB  1 
ATOM   8133  C  CG  . GLU D 1 171 ? 51.079  -2.156  -6.414  1.00 32.63  ? 171 GLU D CG  1 
ATOM   8134  C  CD  . GLU D 1 171 ? 49.757  -2.399  -5.653  1.00 35.56  ? 171 GLU D CD  1 
ATOM   8135  O  OE1 . GLU D 1 171 ? 48.871  -3.115  -6.141  1.00 38.15  ? 171 GLU D OE1 1 
ATOM   8136  O  OE2 . GLU D 1 171 ? 49.555  -1.878  -4.523  1.00 34.88  ? 171 GLU D OE2 1 
ATOM   8137  N  N   . ASP D 1 172 ? 52.410  -5.402  -5.976  1.00 39.26  ? 172 ASP D N   1 
ATOM   8138  C  CA  . ASP D 1 172 ? 53.511  -5.837  -5.122  1.00 37.26  ? 172 ASP D CA  1 
ATOM   8139  C  C   . ASP D 1 172 ? 53.051  -7.105  -4.407  1.00 44.20  ? 172 ASP D C   1 
ATOM   8140  O  O   . ASP D 1 172 ? 52.824  -7.135  -3.176  1.00 44.93  ? 172 ASP D O   1 
ATOM   8141  C  CB  . ASP D 1 172 ? 53.963  -4.753  -4.149  1.00 37.60  ? 172 ASP D CB  1 
ATOM   8142  C  CG  . ASP D 1 172 ? 55.265  -5.012  -3.406  1.00 37.27  ? 172 ASP D CG  1 
ATOM   8143  O  OD1 . ASP D 1 172 ? 55.887  -6.021  -3.706  1.00 45.41  ? 172 ASP D OD1 1 
ATOM   8144  O  OD2 . ASP D 1 172 ? 55.624  -4.232  -2.503  1.00 38.65  ? 172 ASP D OD2 1 
ATOM   8145  N  N   . PRO D 1 173 ? 52.893  -8.200  -5.195  1.00 44.03  ? 173 PRO D N   1 
ATOM   8146  C  CA  . PRO D 1 173 ? 52.001  -9.311  -4.812  1.00 34.35  ? 173 PRO D CA  1 
ATOM   8147  C  C   . PRO D 1 173 ? 52.468  -10.081 -3.585  1.00 36.07  ? 173 PRO D C   1 
ATOM   8148  O  O   . PRO D 1 173 ? 51.689  -10.696 -2.873  1.00 35.99  ? 173 PRO D O   1 
ATOM   8149  C  CB  . PRO D 1 173 ? 52.013  -10.214 -5.997  1.00 35.12  ? 173 PRO D CB  1 
ATOM   8150  C  CG  . PRO D 1 173 ? 52.633  -9.388  -7.095  1.00 39.47  ? 173 PRO D CG  1 
ATOM   8151  C  CD  . PRO D 1 173 ? 53.597  -8.399  -6.477  1.00 39.93  ? 173 PRO D CD  1 
ATOM   8152  N  N   . ALA D 1 174 ? 53.780  -10.065 -3.343  1.00 34.18  ? 174 ALA D N   1 
ATOM   8153  C  CA  . ALA D 1 174 ? 54.280  -10.687 -2.138  1.00 34.98  ? 174 ALA D CA  1 
ATOM   8154  C  C   . ALA D 1 174 ? 53.686  -10.035 -0.867  1.00 38.81  ? 174 ALA D C   1 
ATOM   8155  O  O   . ALA D 1 174 ? 53.722  -10.617 0.209   1.00 35.16  ? 174 ALA D O   1 
ATOM   8156  C  CB  . ALA D 1 174 ? 55.802  -10.526 -2.203  1.00 37.88  ? 174 ALA D CB  1 
ATOM   8157  N  N   . PHE D 1 175 ? 53.272  -8.749  -0.935  1.00 37.85  ? 175 PHE D N   1 
ATOM   8158  C  CA  . PHE D 1 175 ? 52.883  -8.009  0.255   1.00 37.01  ? 175 PHE D CA  1 
ATOM   8159  C  C   . PHE D 1 175 ? 51.439  -7.535  0.155   1.00 40.58  ? 175 PHE D C   1 
ATOM   8160  O  O   . PHE D 1 175 ? 51.027  -6.668  0.914   1.00 35.20  ? 175 PHE D O   1 
ATOM   8161  C  CB  . PHE D 1 175 ? 53.844  -6.829  0.399   1.00 42.17  ? 175 PHE D CB  1 
ATOM   8162  C  CG  . PHE D 1 175 ? 55.257  -7.298  0.739   1.00 45.50  ? 175 PHE D CG  1 
ATOM   8163  C  CD1 . PHE D 1 175 ? 55.530  -7.882  1.976   1.00 36.05  ? 175 PHE D CD1 1 
ATOM   8164  C  CD2 . PHE D 1 175 ? 56.286  -7.162  -0.176  1.00 39.67  ? 175 PHE D CD2 1 
ATOM   8165  C  CE1 . PHE D 1 175 ? 56.786  -8.310  2.298   1.00 32.71  ? 175 PHE D CE1 1 
ATOM   8166  C  CE2 . PHE D 1 175 ? 57.542  -7.630  0.144   1.00 37.81  ? 175 PHE D CE2 1 
ATOM   8167  C  CZ  . PHE D 1 175 ? 57.791  -8.177  1.382   1.00 36.12  ? 175 PHE D CZ  1 
ATOM   8168  N  N   . ALA D 1 176 ? 50.672  -8.106  -0.782  1.00 35.65  ? 176 ALA D N   1 
ATOM   8169  C  CA  . ALA D 1 176 ? 49.234  -7.913  -0.820  1.00 33.22  ? 176 ALA D CA  1 
ATOM   8170  C  C   . ALA D 1 176 ? 48.652  -8.015  0.580   1.00 28.27  ? 176 ALA D C   1 
ATOM   8171  O  O   . ALA D 1 176 ? 48.986  -8.921  1.366   1.00 30.29  ? 176 ALA D O   1 
ATOM   8172  C  CB  . ALA D 1 176 ? 48.582  -8.933  -1.762  1.00 36.80  ? 176 ALA D CB  1 
ATOM   8173  N  N   . GLY D 1 177 ? 47.773  -7.052  0.876   1.00 28.53  ? 177 GLY D N   1 
ATOM   8174  C  CA  . GLY D 1 177 ? 46.998  -7.089  2.110   1.00 29.36  ? 177 GLY D CA  1 
ATOM   8175  C  C   . GLY D 1 177 ? 47.570  -6.121  3.152   1.00 29.74  ? 177 GLY D C   1 
ATOM   8176  O  O   . GLY D 1 177 ? 47.043  -5.899  4.267   1.00 36.36  ? 177 GLY D O   1 
ATOM   8177  N  N   . GLY D 1 178 ? 48.734  -5.598  2.770   1.00 30.70  ? 178 GLY D N   1 
ATOM   8178  C  CA  . GLY D 1 178 ? 49.458  -4.649  3.586   1.00 29.06  ? 178 GLY D CA  1 
ATOM   8179  C  C   . GLY D 1 178 ? 48.981  -3.252  3.245   1.00 25.93  ? 178 GLY D C   1 
ATOM   8180  O  O   . GLY D 1 178 ? 48.104  -3.109  2.393   1.00 23.38  ? 178 GLY D O   1 
ATOM   8181  N  N   . SER D 1 179 ? 49.503  -2.289  4.012   1.00 24.69  ? 179 SER D N   1 
ATOM   8182  C  CA  . SER D 1 179 ? 49.248  -0.890  3.759   1.00 23.22  ? 179 SER D CA  1 
ATOM   8183  C  C   . SER D 1 179 ? 50.420  -0.089  4.277   1.00 21.86  ? 179 SER D C   1 
ATOM   8184  O  O   . SER D 1 179 ? 51.308  -0.660  4.891   1.00 23.22  ? 179 SER D O   1 
ATOM   8185  C  CB  . SER D 1 179 ? 47.943  -0.489  4.411   1.00 27.52  ? 179 SER D CB  1 
ATOM   8186  O  OG  . SER D 1 179 ? 47.504  0.819   4.042   1.00 25.81  ? 179 SER D OG  1 
ATOM   8187  N  N   . TYR D 1 180 ? 50.405  1.219   3.985   1.00 19.49  ? 180 TYR D N   1 
ATOM   8188  C  CA  . TYR D 1 180 ? 51.453  2.126   4.399   1.00 20.78  ? 180 TYR D CA  1 
ATOM   8189  C  C   . TYR D 1 180 ? 50.810  3.156   5.288   1.00 21.50  ? 180 TYR D C   1 
ATOM   8190  O  O   . TYR D 1 180 ? 49.884  3.811   4.848   1.00 22.69  ? 180 TYR D O   1 
ATOM   8191  C  CB  . TYR D 1 180 ? 52.143  2.829   3.215   1.00 21.98  ? 180 TYR D CB  1 
ATOM   8192  C  CG  . TYR D 1 180 ? 52.948  1.857   2.365   1.00 21.55  ? 180 TYR D CG  1 
ATOM   8193  C  CD1 . TYR D 1 180 ? 52.361  1.139   1.320   1.00 23.34  ? 180 TYR D CD1 1 
ATOM   8194  C  CD2 . TYR D 1 180 ? 54.311  1.640   2.623   1.00 26.73  ? 180 TYR D CD2 1 
ATOM   8195  C  CE1 . TYR D 1 180 ? 53.102  0.223   0.567   1.00 23.97  ? 180 TYR D CE1 1 
ATOM   8196  C  CE2 . TYR D 1 180 ? 55.073  0.752   1.865   1.00 26.90  ? 180 TYR D CE2 1 
ATOM   8197  C  CZ  . TYR D 1 180 ? 54.459  0.033   0.840   1.00 26.93  ? 180 TYR D CZ  1 
ATOM   8198  O  OH  . TYR D 1 180 ? 55.227  -0.817  0.104   1.00 25.11  ? 180 TYR D OH  1 
ATOM   8199  N  N   . ALA D 1 181 ? 51.372  3.331   6.486   1.00 18.97  ? 181 ALA D N   1 
ATOM   8200  C  CA  . ALA D 1 181 ? 50.876  4.306   7.411   1.00 18.17  ? 181 ALA D CA  1 
ATOM   8201  C  C   . ALA D 1 181 ? 51.894  5.404   7.640   1.00 19.32  ? 181 ALA D C   1 
ATOM   8202  O  O   . ALA D 1 181 ? 53.074  5.130   7.896   1.00 19.19  ? 181 ALA D O   1 
ATOM   8203  C  CB  . ALA D 1 181 ? 50.572  3.602   8.700   1.00 23.72  ? 181 ALA D CB  1 
ATOM   8204  N  N   . VAL D 1 182 ? 51.400  6.637   7.570   1.00 16.50  ? 182 VAL D N   1 
ATOM   8205  C  CA  . VAL D 1 182 ? 52.185  7.768   7.971   1.00 19.45  ? 182 VAL D CA  1 
ATOM   8206  C  C   . VAL D 1 182 ? 51.533  8.377   9.208   1.00 19.09  ? 182 VAL D C   1 
ATOM   8207  O  O   . VAL D 1 182 ? 50.309  8.570   9.232   1.00 19.96  ? 182 VAL D O   1 
ATOM   8208  C  CB  . VAL D 1 182 ? 52.201  8.808   6.810   1.00 26.48  ? 182 VAL D CB  1 
ATOM   8209  C  CG1 . VAL D 1 182 ? 52.707  10.180  7.268   1.00 27.42  ? 182 VAL D CG1 1 
ATOM   8210  C  CG2 . VAL D 1 182 ? 52.993  8.337   5.585   1.00 28.31  ? 182 VAL D CG2 1 
ATOM   8211  N  N   . VAL D 1 183 ? 52.372  8.757   10.180  1.00 18.32  ? 183 VAL D N   1 
ATOM   8212  C  CA  . VAL D 1 183 ? 51.940  9.365   11.398  1.00 17.49  ? 183 VAL D CA  1 
ATOM   8213  C  C   . VAL D 1 183 ? 52.642  10.697  11.519  1.00 17.02  ? 183 VAL D C   1 
ATOM   8214  O  O   . VAL D 1 183 ? 53.807  10.832  11.232  1.00 18.62  ? 183 VAL D O   1 
ATOM   8215  C  CB  . VAL D 1 183 ? 52.133  8.451   12.642  1.00 19.30  ? 183 VAL D CB  1 
ATOM   8216  C  CG1 . VAL D 1 183 ? 51.356  7.140   12.544  1.00 17.67  ? 183 VAL D CG1 1 
ATOM   8217  C  CG2 . VAL D 1 183 ? 53.582  8.139   12.906  1.00 19.59  ? 183 VAL D CG2 1 
ATOM   8218  N  N   . GLN D 1 184 ? 51.925  11.663  12.062  1.00 19.45  ? 184 GLN D N   1 
ATOM   8219  C  CA  . GLN D 1 184 ? 52.494  12.912  12.497  1.00 18.66  ? 184 GLN D CA  1 
ATOM   8220  C  C   . GLN D 1 184 ? 51.712  13.391  13.735  1.00 21.72  ? 184 GLN D C   1 
ATOM   8221  O  O   . GLN D 1 184 ? 50.499  13.524  13.699  1.00 22.11  ? 184 GLN D O   1 
ATOM   8222  C  CB  . GLN D 1 184 ? 52.337  13.971  11.400  1.00 21.37  ? 184 GLN D CB  1 
ATOM   8223  C  CG  . GLN D 1 184 ? 53.092  13.758  10.103  1.00 20.12  ? 184 GLN D CG  1 
ATOM   8224  C  CD  . GLN D 1 184 ? 52.877  14.989  9.258   1.00 20.35  ? 184 GLN D CD  1 
ATOM   8225  O  OE1 . GLN D 1 184 ? 51.756  15.222  8.800   1.00 17.27  ? 184 GLN D OE1 1 
ATOM   8226  N  NE2 . GLN D 1 184 ? 53.909  15.832  9.142   1.00 19.57  ? 184 GLN D NE2 1 
ATOM   8227  N  N   . LYS D 1 185 ? 52.417  13.797  14.799  1.00 19.33  ? 185 LYS D N   1 
ATOM   8228  C  CA  . LYS D 1 185 ? 51.767  14.429  15.901  1.00 17.90  ? 185 LYS D CA  1 
ATOM   8229  C  C   . LYS D 1 185 ? 51.800  15.919  15.655  1.00 19.88  ? 185 LYS D C   1 
ATOM   8230  O  O   . LYS D 1 185 ? 52.874  16.504  15.582  1.00 20.20  ? 185 LYS D O   1 
ATOM   8231  C  CB  . LYS D 1 185 ? 52.553  14.049  17.152  1.00 19.21  ? 185 LYS D CB  1 
ATOM   8232  C  CG  . LYS D 1 185 ? 52.040  14.734  18.353  1.00 22.90  ? 185 LYS D CG  1 
ATOM   8233  C  CD  . LYS D 1 185 ? 52.269  14.005  19.664  1.00 31.11  ? 185 LYS D CD  1 
ATOM   8234  C  CE  . LYS D 1 185 ? 53.665  14.127  20.071  1.00 30.30  ? 185 LYS D CE  1 
ATOM   8235  N  NZ  . LYS D 1 185 ? 53.751  13.345  21.298  1.00 27.63  ? 185 LYS D NZ  1 
ATOM   8236  N  N   . TYR D 1 186 ? 50.636  16.575  15.711  1.00 21.31  ? 186 TYR D N   1 
ATOM   8237  C  CA  . TYR D 1 186 ? 50.550  18.036  15.576  1.00 19.97  ? 186 TYR D CA  1 
ATOM   8238  C  C   . TYR D 1 186 ? 50.097  18.686  16.884  1.00 21.24  ? 186 TYR D C   1 
ATOM   8239  O  O   . TYR D 1 186 ? 49.192  18.188  17.549  1.00 20.36  ? 186 TYR D O   1 
ATOM   8240  C  CB  . TYR D 1 186 ? 49.522  18.492  14.526  1.00 18.40  ? 186 TYR D CB  1 
ATOM   8241  C  CG  . TYR D 1 186 ? 49.927  18.254  13.084  1.00 17.94  ? 186 TYR D CG  1 
ATOM   8242  C  CD1 . TYR D 1 186 ? 49.727  17.018  12.483  1.00 16.73  ? 186 TYR D CD1 1 
ATOM   8243  C  CD2 . TYR D 1 186 ? 50.521  19.275  12.365  1.00 15.75  ? 186 TYR D CD2 1 
ATOM   8244  C  CE1 . TYR D 1 186 ? 50.101  16.835  11.160  1.00 20.13  ? 186 TYR D CE1 1 
ATOM   8245  C  CE2 . TYR D 1 186 ? 50.850  19.107  11.040  1.00 17.72  ? 186 TYR D CE2 1 
ATOM   8246  C  CZ  . TYR D 1 186 ? 50.658  17.891  10.427  1.00 18.83  ? 186 TYR D CZ  1 
ATOM   8247  O  OH  . TYR D 1 186 ? 51.077  17.713  9.139   1.00 22.40  ? 186 TYR D OH  1 
ATOM   8248  N  N   . LEU D 1 187 ? 50.686  19.843  17.192  1.00 20.77  ? 187 LEU D N   1 
ATOM   8249  C  CA  . LEU D 1 187 ? 50.213  20.667  18.281  1.00 21.62  ? 187 LEU D CA  1 
ATOM   8250  C  C   . LEU D 1 187 ? 49.603  21.951  17.715  1.00 22.39  ? 187 LEU D C   1 
ATOM   8251  O  O   . LEU D 1 187 ? 50.142  22.522  16.811  1.00 26.47  ? 187 LEU D O   1 
ATOM   8252  C  CB  . LEU D 1 187 ? 51.368  20.931  19.256  1.00 24.74  ? 187 LEU D CB  1 
ATOM   8253  C  CG  . LEU D 1 187 ? 51.934  19.699  19.985  1.00 26.49  ? 187 LEU D CG  1 
ATOM   8254  C  CD1 . LEU D 1 187 ? 53.258  19.930  20.584  1.00 29.12  ? 187 LEU D CD1 1 
ATOM   8255  C  CD2 . LEU D 1 187 ? 50.981  19.293  21.034  1.00 28.69  ? 187 LEU D CD2 1 
ATOM   8256  N  N   . HIS D 1 188 ? 48.545  22.479  18.335  1.00 22.38  ? 188 HIS D N   1 
ATOM   8257  C  CA  . HIS D 1 188 ? 47.775  23.564  17.782  1.00 23.08  ? 188 HIS D CA  1 
ATOM   8258  C  C   . HIS D 1 188 ? 47.995  24.775  18.652  1.00 22.65  ? 188 HIS D C   1 
ATOM   8259  O  O   . HIS D 1 188 ? 48.064  24.648  19.837  1.00 19.97  ? 188 HIS D O   1 
ATOM   8260  C  CB  . HIS D 1 188 ? 46.248  23.269  17.720  1.00 22.38  ? 188 HIS D CB  1 
ATOM   8261  C  CG  . HIS D 1 188 ? 45.896  22.199  16.735  1.00 20.69  ? 188 HIS D CG  1 
ATOM   8262  N  ND1 . HIS D 1 188 ? 46.088  22.359  15.390  1.00 18.87  ? 188 HIS D ND1 1 
ATOM   8263  C  CD2 . HIS D 1 188 ? 45.494  20.908  16.901  1.00 20.35  ? 188 HIS D CD2 1 
ATOM   8264  C  CE1 . HIS D 1 188 ? 45.710  21.224  14.780  1.00 21.91  ? 188 HIS D CE1 1 
ATOM   8265  N  NE2 . HIS D 1 188 ? 45.393  20.313  15.696  1.00 19.84  ? 188 HIS D NE2 1 
ATOM   8266  N  N   . ASP D 1 189 ? 47.997  25.946  18.003  1.00 22.57  ? 189 ASP D N   1 
ATOM   8267  C  CA  . ASP D 1 189 ? 47.905  27.239  18.605  1.00 21.71  ? 189 ASP D CA  1 
ATOM   8268  C  C   . ASP D 1 189 ? 46.432  27.623  18.691  1.00 21.54  ? 189 ASP D C   1 
ATOM   8269  O  O   . ASP D 1 189 ? 45.913  28.375  17.893  1.00 18.73  ? 189 ASP D O   1 
ATOM   8270  C  CB  . ASP D 1 189 ? 48.724  28.226  17.822  1.00 22.51  ? 189 ASP D CB  1 
ATOM   8271  C  CG  . ASP D 1 189 ? 48.815  29.586  18.490  1.00 27.23  ? 189 ASP D CG  1 
ATOM   8272  O  OD1 . ASP D 1 189 ? 48.072  29.824  19.471  1.00 27.73  ? 189 ASP D OD1 1 
ATOM   8273  O  OD2 . ASP D 1 189 ? 49.620  30.384  17.985  1.00 36.28  ? 189 ASP D OD2 1 
ATOM   8274  N  N   . ILE D 1 190 ? 45.815  27.195  19.782  1.00 21.60  ? 190 ILE D N   1 
ATOM   8275  C  CA  . ILE D 1 190 ? 44.404  27.361  19.986  1.00 23.82  ? 190 ILE D CA  1 
ATOM   8276  C  C   . ILE D 1 190 ? 44.052  28.827  20.216  1.00 23.68  ? 190 ILE D C   1 
ATOM   8277  O  O   . ILE D 1 190 ? 42.982  29.281  19.763  1.00 28.26  ? 190 ILE D O   1 
ATOM   8278  C  CB  . ILE D 1 190 ? 43.912  26.412  21.093  1.00 23.49  ? 190 ILE D CB  1 
ATOM   8279  C  CG1 . ILE D 1 190 ? 44.003  25.001  20.611  1.00 26.67  ? 190 ILE D CG1 1 
ATOM   8280  C  CG2 . ILE D 1 190 ? 42.475  26.759  21.442  1.00 23.19  ? 190 ILE D CG2 1 
ATOM   8281  C  CD1 . ILE D 1 190 ? 42.971  24.665  19.520  1.00 25.40  ? 190 ILE D CD1 1 
ATOM   8282  N  N   . ASP D 1 191 ? 44.905  29.584  20.884  1.00 21.26  ? 191 ASP D N   1 
ATOM   8283  C  CA  . ASP D 1 191 ? 44.564  30.977  21.161  1.00 27.63  ? 191 ASP D CA  1 
ATOM   8284  C  C   . ASP D 1 191 ? 44.496  31.714  19.831  1.00 25.39  ? 191 ASP D C   1 
ATOM   8285  O  O   . ASP D 1 191 ? 43.577  32.472  19.595  1.00 27.98  ? 191 ASP D O   1 
ATOM   8286  C  CB  . ASP D 1 191 ? 45.548  31.734  22.044  1.00 33.80  ? 191 ASP D CB  1 
ATOM   8287  C  CG  . ASP D 1 191 ? 45.687  31.245  23.488  1.00 46.83  ? 191 ASP D CG  1 
ATOM   8288  O  OD1 . ASP D 1 191 ? 44.771  30.567  23.994  1.00 49.89  ? 191 ASP D OD1 1 
ATOM   8289  O  OD2 . ASP D 1 191 ? 46.740  31.494  24.113  1.00 53.78  ? 191 ASP D OD2 1 
ATOM   8290  N  N   . ALA D 1 192 ? 45.435  31.461  18.923  1.00 24.75  ? 192 ALA D N   1 
ATOM   8291  C  CA  . ALA D 1 192 ? 45.364  32.132  17.626  1.00 22.71  ? 192 ALA D CA  1 
ATOM   8292  C  C   . ALA D 1 192 ? 44.123  31.704  16.845  1.00 23.75  ? 192 ALA D C   1 
ATOM   8293  O  O   . ALA D 1 192 ? 43.495  32.502  16.234  1.00 26.92  ? 192 ALA D O   1 
ATOM   8294  C  CB  . ALA D 1 192 ? 46.621  31.875  16.838  1.00 21.30  ? 192 ALA D CB  1 
ATOM   8295  N  N   . TRP D 1 193 ? 43.835  30.411  16.804  1.00 23.80  ? 193 TRP D N   1 
ATOM   8296  C  CA  . TRP D 1 193 ? 42.697  29.854  16.078  1.00 28.32  ? 193 TRP D CA  1 
ATOM   8297  C  C   . TRP D 1 193 ? 41.362  30.447  16.553  1.00 27.00  ? 193 TRP D C   1 
ATOM   8298  O  O   . TRP D 1 193 ? 40.541  30.799  15.729  1.00 25.90  ? 193 TRP D O   1 
ATOM   8299  C  CB  . TRP D 1 193 ? 42.692  28.347  16.304  1.00 24.56  ? 193 TRP D CB  1 
ATOM   8300  C  CG  . TRP D 1 193 ? 41.589  27.619  15.609  1.00 23.04  ? 193 TRP D CG  1 
ATOM   8301  C  CD1 . TRP D 1 193 ? 40.583  26.907  16.200  1.00 24.34  ? 193 TRP D CD1 1 
ATOM   8302  C  CD2 . TRP D 1 193 ? 41.464  27.426  14.193  1.00 21.42  ? 193 TRP D CD2 1 
ATOM   8303  N  NE1 . TRP D 1 193 ? 39.811  26.302  15.233  1.00 23.63  ? 193 TRP D NE1 1 
ATOM   8304  C  CE2 . TRP D 1 193 ? 40.315  26.614  14.000  1.00 22.25  ? 193 TRP D CE2 1 
ATOM   8305  C  CE3 . TRP D 1 193 ? 42.197  27.850  13.089  1.00 23.15  ? 193 TRP D CE3 1 
ATOM   8306  C  CZ2 . TRP D 1 193 ? 39.895  26.220  12.744  1.00 21.94  ? 193 TRP D CZ2 1 
ATOM   8307  C  CZ3 . TRP D 1 193 ? 41.766  27.493  11.830  1.00 23.38  ? 193 TRP D CZ3 1 
ATOM   8308  C  CH2 . TRP D 1 193 ? 40.614  26.699  11.656  1.00 25.83  ? 193 TRP D CH2 1 
ATOM   8309  N  N   . GLU D 1 194 ? 41.204  30.611  17.866  1.00 29.41  ? 194 GLU D N   1 
ATOM   8310  C  CA  . GLU D 1 194 ? 39.991  31.120  18.458  1.00 36.47  ? 194 GLU D CA  1 
ATOM   8311  C  C   . GLU D 1 194 ? 39.872  32.614  18.227  1.00 34.79  ? 194 GLU D C   1 
ATOM   8312  O  O   . GLU D 1 194 ? 38.791  33.159  18.382  1.00 39.12  ? 194 GLU D O   1 
ATOM   8313  C  CB  . GLU D 1 194 ? 39.866  30.745  19.930  1.00 36.28  ? 194 GLU D CB  1 
ATOM   8314  C  CG  . GLU D 1 194 ? 38.977  29.521  20.098  1.00 50.17  ? 194 GLU D CG  1 
ATOM   8315  C  CD  . GLU D 1 194 ? 39.377  28.773  21.365  1.00 72.87  ? 194 GLU D CD  1 
ATOM   8316  O  OE1 . GLU D 1 194 ? 40.269  29.289  22.082  1.00 88.29  ? 194 GLU D OE1 1 
ATOM   8317  O  OE2 . GLU D 1 194 ? 38.854  27.677  21.633  1.00 81.48  ? 194 GLU D OE2 1 
ATOM   8318  N  N   . GLY D 1 195 ? 40.907  33.251  17.723  1.00 29.20  ? 195 GLY D N   1 
ATOM   8319  C  CA  . GLY D 1 195 ? 40.728  34.645  17.378  1.00 27.63  ? 195 GLY D CA  1 
ATOM   8320  C  C   . GLY D 1 195 ? 40.253  34.845  15.951  1.00 25.55  ? 195 GLY D C   1 
ATOM   8321  O  O   . GLY D 1 195 ? 40.011  35.953  15.564  1.00 31.81  ? 195 GLY D O   1 
ATOM   8322  N  N   . LEU D 1 196 ? 40.191  33.811  15.131  1.00 24.01  ? 196 LEU D N   1 
ATOM   8323  C  CA  . LEU D 1 196 ? 39.537  33.908  13.837  1.00 24.50  ? 196 LEU D CA  1 
ATOM   8324  C  C   . LEU D 1 196 ? 38.026  33.878  14.023  1.00 21.49  ? 196 LEU D C   1 
ATOM   8325  O  O   . LEU D 1 196 ? 37.554  33.233  14.918  1.00 24.03  ? 196 LEU D O   1 
ATOM   8326  C  CB  . LEU D 1 196 ? 40.010  32.760  12.950  1.00 23.96  ? 196 LEU D CB  1 
ATOM   8327  C  CG  . LEU D 1 196 ? 41.500  32.712  12.589  1.00 28.24  ? 196 LEU D CG  1 
ATOM   8328  C  CD1 . LEU D 1 196 ? 41.709  31.803  11.384  1.00 32.41  ? 196 LEU D CD1 1 
ATOM   8329  C  CD2 . LEU D 1 196 ? 41.986  34.035  12.280  1.00 30.41  ? 196 LEU D CD2 1 
ATOM   8330  N  N   . SER D 1 197 ? 37.278  34.532  13.146  1.00 20.93  ? 197 SER D N   1 
ATOM   8331  C  CA  . SER D 1 197 ? 35.845  34.328  13.068  1.00 22.63  ? 197 SER D CA  1 
ATOM   8332  C  C   . SER D 1 197 ? 35.589  32.941  12.524  1.00 21.58  ? 197 SER D C   1 
ATOM   8333  O  O   . SER D 1 197 ? 36.436  32.341  11.902  1.00 24.30  ? 197 SER D O   1 
ATOM   8334  C  CB  . SER D 1 197 ? 35.185  35.324  12.158  1.00 24.37  ? 197 SER D CB  1 
ATOM   8335  O  OG  . SER D 1 197 ? 35.667  35.156  10.838  1.00 25.57  ? 197 SER D OG  1 
ATOM   8336  N  N   . VAL D 1 198 ? 34.381  32.449  12.698  1.00 23.08  ? 198 VAL D N   1 
ATOM   8337  C  CA  . VAL D 1 198 ? 34.015  31.152  12.153  1.00 23.33  ? 198 VAL D CA  1 
ATOM   8338  C  C   . VAL D 1 198 ? 34.164  31.166  10.631  1.00 21.67  ? 198 VAL D C   1 
ATOM   8339  O  O   . VAL D 1 198 ? 34.640  30.172  10.103  1.00 22.27  ? 198 VAL D O   1 
ATOM   8340  C  CB  . VAL D 1 198 ? 32.610  30.723  12.627  1.00 21.44  ? 198 VAL D CB  1 
ATOM   8341  C  CG1 . VAL D 1 198 ? 32.043  29.548  11.789  1.00 19.52  ? 198 VAL D CG1 1 
ATOM   8342  C  CG2 . VAL D 1 198 ? 32.641  30.460  14.138  1.00 21.85  ? 198 VAL D CG2 1 
ATOM   8343  N  N   . GLU D 1 199 ? 33.822  32.283  9.973   1.00 22.10  ? 199 GLU D N   1 
ATOM   8344  C  CA  . GLU D 1 199 ? 33.877  32.389  8.517   1.00 25.04  ? 199 GLU D CA  1 
ATOM   8345  C  C   . GLU D 1 199 ? 35.334  32.229  8.069   1.00 25.03  ? 199 GLU D C   1 
ATOM   8346  O  O   . GLU D 1 199 ? 35.601  31.602  7.052   1.00 26.21  ? 199 GLU D O   1 
ATOM   8347  C  CB  . GLU D 1 199 ? 33.259  33.634  7.857   1.00 29.26  ? 199 GLU D CB  1 
ATOM   8348  C  CG  . GLU D 1 199 ? 31.823  33.953  8.316   1.00 50.70  ? 199 GLU D CG  1 
ATOM   8349  C  CD  . GLU D 1 199 ? 31.189  33.860  9.776   1.00 46.47  ? 199 GLU D CD  1 
ATOM   8350  O  OE1 . GLU D 1 199 ? 31.933  34.420  10.688  1.00 30.83  ? 199 GLU D OE1 1 
ATOM   8351  O  OE2 . GLU D 1 199 ? 29.964  33.365  10.036  1.00 32.59  ? 199 GLU D OE2 1 
ATOM   8352  N  N   . ALA D 1 200 ? 36.279  32.767  8.843   1.00 23.39  ? 200 ALA D N   1 
ATOM   8353  C  CA  . ALA D 1 200 ? 37.700  32.713  8.515   1.00 25.09  ? 200 ALA D CA  1 
ATOM   8354  C  C   . ALA D 1 200 ? 38.249  31.305  8.751   1.00 25.69  ? 200 ALA D C   1 
ATOM   8355  O  O   . ALA D 1 200 ? 39.124  30.829  8.034   1.00 25.22  ? 200 ALA D O   1 
ATOM   8356  C  CB  . ALA D 1 200 ? 38.466  33.763  9.343   1.00 23.42  ? 200 ALA D CB  1 
ATOM   8357  N  N   . GLN D 1 201 ? 37.718  30.626  9.772   1.00 25.40  ? 201 GLN D N   1 
ATOM   8358  C  CA  . GLN D 1 201 ? 38.124  29.262  10.030  1.00 23.31  ? 201 GLN D CA  1 
ATOM   8359  C  C   . GLN D 1 201 ? 37.678  28.384  8.865   1.00 22.41  ? 201 GLN D C   1 
ATOM   8360  O  O   . GLN D 1 201 ? 38.404  27.468  8.451   1.00 20.84  ? 201 GLN D O   1 
ATOM   8361  C  CB  . GLN D 1 201 ? 37.536  28.753  11.341  1.00 21.17  ? 201 GLN D CB  1 
ATOM   8362  C  CG  . GLN D 1 201 ? 38.038  29.481  12.578  1.00 19.40  ? 201 GLN D CG  1 
ATOM   8363  C  CD  . GLN D 1 201 ? 37.488  28.885  13.846  1.00 20.28  ? 201 GLN D CD  1 
ATOM   8364  O  OE1 . GLN D 1 201 ? 36.579  28.063  13.863  1.00 21.96  ? 201 GLN D OE1 1 
ATOM   8365  N  NE2 . GLN D 1 201 ? 38.095  29.219  14.943  1.00 19.09  ? 201 GLN D NE2 1 
ATOM   8366  N  N   . GLU D 1 202 ? 36.454  28.634  8.399   1.00 23.44  ? 202 GLU D N   1 
ATOM   8367  C  CA  . GLU D 1 202 ? 35.903  27.844  7.315   1.00 25.08  ? 202 GLU D CA  1 
ATOM   8368  C  C   . GLU D 1 202 ? 36.757  27.980  6.043   1.00 24.32  ? 202 GLU D C   1 
ATOM   8369  O  O   . GLU D 1 202 ? 36.854  27.049  5.235   1.00 24.28  ? 202 GLU D O   1 
ATOM   8370  C  CB  . GLU D 1 202 ? 34.454  28.285  7.087   1.00 26.14  ? 202 GLU D CB  1 
ATOM   8371  C  CG  . GLU D 1 202 ? 33.472  27.739  8.123   1.00 26.95  ? 202 GLU D CG  1 
ATOM   8372  C  CD  . GLU D 1 202 ? 32.083  28.341  8.054   1.00 26.06  ? 202 GLU D CD  1 
ATOM   8373  O  OE1 . GLU D 1 202 ? 31.901  29.401  7.441   1.00 24.02  ? 202 GLU D OE1 1 
ATOM   8374  O  OE2 . GLU D 1 202 ? 31.167  27.704  8.609   1.00 24.38  ? 202 GLU D OE2 1 
ATOM   8375  N  N   . ARG D 1 203 ? 37.356  29.153  5.855   1.00 22.93  ? 203 ARG D N   1 
ATOM   8376  C  CA  . ARG D 1 203 ? 38.190  29.411  4.698   1.00 25.79  ? 203 ARG D CA  1 
ATOM   8377  C  C   . ARG D 1 203 ? 39.539  28.711  4.835   1.00 23.94  ? 203 ARG D C   1 
ATOM   8378  O  O   . ARG D 1 203 ? 40.151  28.354  3.810   1.00 22.31  ? 203 ARG D O   1 
ATOM   8379  C  CB  . ARG D 1 203 ? 38.311  30.938  4.547   1.00 31.86  ? 203 ARG D CB  1 
ATOM   8380  C  CG  . ARG D 1 203 ? 37.228  31.563  3.660   1.00 42.94  ? 203 ARG D CG  1 
ATOM   8381  C  CD  . ARG D 1 203 ? 37.664  32.855  2.859   1.00 59.80  ? 203 ARG D CD  1 
ATOM   8382  N  NE  . ARG D 1 203 ? 37.120  33.981  3.626   1.00 75.47  ? 203 ARG D NE  1 
ATOM   8383  C  CZ  . ARG D 1 203 ? 37.497  34.459  4.838   1.00 78.61  ? 203 ARG D CZ  1 
ATOM   8384  N  NH1 . ARG D 1 203 ? 38.749  34.380  5.277   1.00 77.11  ? 203 ARG D NH1 1 
ATOM   8385  N  NH2 . ARG D 1 203 ? 36.620  35.123  5.584   1.00 71.46  ? 203 ARG D NH2 1 
ATOM   8386  N  N   . VAL D 1 204 ? 39.963  28.439  6.086   1.00 21.07  ? 204 VAL D N   1 
ATOM   8387  C  CA  . VAL D 1 204 ? 41.162  27.656  6.325   1.00 20.30  ? 204 VAL D CA  1 
ATOM   8388  C  C   . VAL D 1 204 ? 40.921  26.185  5.975   1.00 22.57  ? 204 VAL D C   1 
ATOM   8389  O  O   . VAL D 1 204 ? 41.757  25.529  5.305   1.00 20.53  ? 204 VAL D O   1 
ATOM   8390  C  CB  . VAL D 1 204 ? 41.642  27.833  7.778   1.00 20.30  ? 204 VAL D CB  1 
ATOM   8391  C  CG1 . VAL D 1 204 ? 42.753  26.850  8.132   1.00 18.87  ? 204 VAL D CG1 1 
ATOM   8392  C  CG2 . VAL D 1 204 ? 42.084  29.286  8.036   1.00 21.32  ? 204 VAL D CG2 1 
ATOM   8393  N  N   . ILE D 1 205 ? 39.779  25.655  6.443   1.00 19.13  ? 205 ILE D N   1 
ATOM   8394  C  CA  . ILE D 1 205 ? 39.554  24.237  6.287   1.00 20.31  ? 205 ILE D CA  1 
ATOM   8395  C  C   . ILE D 1 205 ? 39.014  23.934  4.873   1.00 21.38  ? 205 ILE D C   1 
ATOM   8396  O  O   . ILE D 1 205 ? 39.478  23.006  4.199   1.00 20.75  ? 205 ILE D O   1 
ATOM   8397  C  CB  . ILE D 1 205 ? 38.586  23.800  7.394   1.00 21.70  ? 205 ILE D CB  1 
ATOM   8398  C  CG1 . ILE D 1 205 ? 39.178  24.050  8.782   1.00 23.56  ? 205 ILE D CG1 1 
ATOM   8399  C  CG2 . ILE D 1 205 ? 38.153  22.334  7.215   1.00 21.90  ? 205 ILE D CG2 1 
ATOM   8400  C  CD1 . ILE D 1 205 ? 40.374  23.166  9.087   1.00 24.19  ? 205 ILE D CD1 1 
ATOM   8401  N  N   . GLY D 1 206 ? 37.980  24.693  4.449   1.00 21.47  ? 206 GLY D N   1 
ATOM   8402  C  CA  . GLY D 1 206 ? 37.318  24.432  3.190   1.00 21.22  ? 206 GLY D CA  1 
ATOM   8403  C  C   . GLY D 1 206 ? 35.930  23.807  3.332   1.00 22.48  ? 206 GLY D C   1 
ATOM   8404  O  O   . GLY D 1 206 ? 35.291  23.451  2.369   1.00 23.59  ? 206 GLY D O   1 
ATOM   8405  N  N   . ARG D 1 207 ? 35.410  23.713  4.543   1.00 26.18  ? 207 ARG D N   1 
ATOM   8406  C  CA  . ARG D 1 207 ? 34.075  23.213  4.801   1.00 22.19  ? 207 ARG D CA  1 
ATOM   8407  C  C   . ARG D 1 207 ? 33.409  24.131  5.802   1.00 21.77  ? 207 ARG D C   1 
ATOM   8408  O  O   . ARG D 1 207 ? 34.068  24.880  6.485   1.00 21.13  ? 207 ARG D O   1 
ATOM   8409  C  CB  . ARG D 1 207 ? 34.139  21.804  5.378   1.00 21.84  ? 207 ARG D CB  1 
ATOM   8410  C  CG  . ARG D 1 207 ? 34.847  20.888  4.426   1.00 21.86  ? 207 ARG D CG  1 
ATOM   8411  C  CD  . ARG D 1 207 ? 34.837  19.528  5.084   1.00 24.44  ? 207 ARG D CD  1 
ATOM   8412  N  NE  . ARG D 1 207 ? 33.586  18.770  4.960   1.00 25.03  ? 207 ARG D NE  1 
ATOM   8413  C  CZ  . ARG D 1 207 ? 33.115  18.070  3.893   1.00 24.51  ? 207 ARG D CZ  1 
ATOM   8414  N  NH1 . ARG D 1 207 ? 33.892  17.761  2.908   1.00 29.11  ? 207 ARG D NH1 1 
ATOM   8415  N  NH2 . ARG D 1 207 ? 31.888  17.619  3.777   1.00 24.71  ? 207 ARG D NH2 1 
ATOM   8416  N  N   . ARG D 1 208 ? 32.101  24.026  5.933   1.00 29.11  ? 208 ARG D N   1 
ATOM   8417  C  CA  . ARG D 1 208 ? 31.347  24.831  6.897   1.00 27.00  ? 208 ARG D CA  1 
ATOM   8418  C  C   . ARG D 1 208 ? 31.488  24.174  8.252   1.00 24.83  ? 208 ARG D C   1 
ATOM   8419  O  O   . ARG D 1 208 ? 31.486  22.940  8.366   1.00 26.17  ? 208 ARG D O   1 
ATOM   8420  C  CB  . ARG D 1 208 ? 29.848  24.825  6.606   1.00 28.69  ? 208 ARG D CB  1 
ATOM   8421  C  CG  . ARG D 1 208 ? 29.417  25.426  5.282   1.00 31.95  ? 208 ARG D CG  1 
ATOM   8422  C  CD  . ARG D 1 208 ? 29.845  26.860  5.110   1.00 46.24  ? 208 ARG D CD  1 
ATOM   8423  N  NE  . ARG D 1 208 ? 29.265  27.774  6.100   1.00 60.16  ? 208 ARG D NE  1 
ATOM   8424  C  CZ  . ARG D 1 208 ? 27.995  28.144  6.150   1.00 70.16  ? 208 ARG D CZ  1 
ATOM   8425  N  NH1 . ARG D 1 208 ? 27.182  27.879  5.137   1.00 73.09  ? 208 ARG D NH1 1 
ATOM   8426  N  NH2 . ARG D 1 208 ? 27.562  28.812  7.209   1.00 64.02  ? 208 ARG D NH2 1 
ATOM   8427  N  N   . LYS D 1 209 ? 31.557  24.986  9.297   1.00 22.62  ? 209 LYS D N   1 
ATOM   8428  C  CA  . LYS D 1 209 ? 31.883  24.437  10.604  1.00 24.93  ? 209 LYS D CA  1 
ATOM   8429  C  C   . LYS D 1 209 ? 30.725  23.646  11.210  1.00 25.47  ? 209 LYS D C   1 
ATOM   8430  O  O   . LYS D 1 209 ? 30.907  22.483  11.586  1.00 28.17  ? 209 LYS D O   1 
ATOM   8431  C  CB  . LYS D 1 209 ? 32.397  25.532  11.529  1.00 23.33  ? 209 LYS D CB  1 
ATOM   8432  C  CG  . LYS D 1 209 ? 32.961  25.058  12.816  1.00 21.28  ? 209 LYS D CG  1 
ATOM   8433  C  CD  . LYS D 1 209 ? 33.635  26.188  13.565  1.00 22.43  ? 209 LYS D CD  1 
ATOM   8434  C  CE  . LYS D 1 209 ? 34.510  25.505  14.616  1.00 24.37  ? 209 LYS D CE  1 
ATOM   8435  N  NZ  . LYS D 1 209 ? 35.069  26.478  15.564  1.00 24.05  ? 209 LYS D NZ  1 
ATOM   8436  N  N   . MET D 1 210 ? 29.563  24.287  11.324  1.00 25.30  ? 210 MET D N   1 
ATOM   8437  C  CA  . MET D 1 210 ? 28.411  23.702  12.013  1.00 33.68  ? 210 MET D CA  1 
ATOM   8438  C  C   . MET D 1 210 ? 27.885  22.493  11.193  1.00 34.38  ? 210 MET D C   1 
ATOM   8439  O  O   . MET D 1 210 ? 27.799  21.365  11.707  1.00 30.65  ? 210 MET D O   1 
ATOM   8440  C  CB  . MET D 1 210 ? 27.457  24.875  12.337  1.00 43.77  ? 210 MET D CB  1 
ATOM   8441  C  CG  . MET D 1 210 ? 26.005  24.604  12.637  1.00 67.54  ? 210 MET D CG  1 
ATOM   8442  S  SD  . MET D 1 210 ? 25.402  24.741  14.336  1.00 91.16  ? 210 MET D SD  1 
ATOM   8443  C  CE  . MET D 1 210 ? 23.877  23.795  14.084  1.00 83.89  ? 210 MET D CE  1 
ATOM   8444  N  N   . THR D 1 211 ? 27.677  22.674  9.863   1.00 27.89  ? 211 THR D N   1 
ATOM   8445  C  CA  . THR D 1 211 ? 26.933  21.716  9.062   1.00 27.58  ? 211 THR D CA  1 
ATOM   8446  C  C   . THR D 1 211 ? 27.844  20.761  8.309   1.00 27.62  ? 211 THR D C   1 
ATOM   8447  O  O   . THR D 1 211 ? 27.366  19.856  7.652   1.00 26.97  ? 211 THR D O   1 
ATOM   8448  C  CB  . THR D 1 211 ? 26.059  22.465  8.061   1.00 30.66  ? 211 THR D CB  1 
ATOM   8449  O  OG1 . THR D 1 211 ? 26.844  23.243  7.163   1.00 30.25  ? 211 THR D OG1 1 
ATOM   8450  C  CG2 . THR D 1 211 ? 25.165  23.461  8.751   1.00 30.58  ? 211 THR D CG2 1 
ATOM   8451  N  N   . ASP D 1 212 ? 29.157  21.020  8.284   1.00 27.58  ? 212 ASP D N   1 
ATOM   8452  C  CA  . ASP D 1 212 ? 30.098  20.147  7.587   1.00 25.55  ? 212 ASP D CA  1 
ATOM   8453  C  C   . ASP D 1 212 ? 29.815  20.081  6.098   1.00 24.61  ? 212 ASP D C   1 
ATOM   8454  O  O   . ASP D 1 212 ? 30.198  19.116  5.476   1.00 24.56  ? 212 ASP D O   1 
ATOM   8455  C  CB  . ASP D 1 212 ? 30.137  18.729  8.148   1.00 22.04  ? 212 ASP D CB  1 
ATOM   8456  C  CG  . ASP D 1 212 ? 31.407  17.927  7.880   1.00 23.54  ? 212 ASP D CG  1 
ATOM   8457  O  OD1 . ASP D 1 212 ? 32.469  18.560  7.541   1.00 25.94  ? 212 ASP D OD1 1 
ATOM   8458  O  OD2 . ASP D 1 212 ? 31.341  16.694  8.043   1.00 23.79  ? 212 ASP D OD2 1 
ATOM   8459  N  N   . VAL D 1 213 ? 29.241  21.112  5.485   1.00 25.87  ? 213 VAL D N   1 
ATOM   8460  C  CA  . VAL D 1 213 ? 29.051  21.058  4.036   1.00 27.78  ? 213 VAL D CA  1 
ATOM   8461  C  C   . VAL D 1 213 ? 30.290  21.620  3.353   1.00 25.77  ? 213 VAL D C   1 
ATOM   8462  O  O   . VAL D 1 213 ? 30.759  22.685  3.774   1.00 26.07  ? 213 VAL D O   1 
ATOM   8463  C  CB  . VAL D 1 213 ? 27.781  21.811  3.593   1.00 29.44  ? 213 VAL D CB  1 
ATOM   8464  C  CG1 . VAL D 1 213 ? 27.645  21.866  2.057   1.00 28.34  ? 213 VAL D CG1 1 
ATOM   8465  C  CG2 . VAL D 1 213 ? 26.553  21.149  4.211   1.00 33.39  ? 213 VAL D CG2 1 
ATOM   8466  N  N   . GLU D 1 214 ? 30.771  20.960  2.290   1.00 22.77  ? 214 GLU D N   1 
ATOM   8467  C  CA  . GLU D 1 214 ? 31.914  21.517  1.576   1.00 29.57  ? 214 GLU D CA  1 
ATOM   8468  C  C   . GLU D 1 214 ? 31.647  22.906  0.988   1.00 24.89  ? 214 GLU D C   1 
ATOM   8469  O  O   . GLU D 1 214 ? 30.568  23.117  0.553   1.00 23.96  ? 214 GLU D O   1 
ATOM   8470  C  CB  . GLU D 1 214 ? 32.363  20.484  0.565   1.00 32.44  ? 214 GLU D CB  1 
ATOM   8471  C  CG  . GLU D 1 214 ? 33.594  20.880  -0.262  1.00 35.44  ? 214 GLU D CG  1 
ATOM   8472  C  CD  . GLU D 1 214 ? 34.121  19.614  -0.952  1.00 35.63  ? 214 GLU D CD  1 
ATOM   8473  O  OE1 . GLU D 1 214 ? 33.608  18.407  -0.804  1.00 42.92  ? 214 GLU D OE1 1 
ATOM   8474  O  OE2 . GLU D 1 214 ? 35.122  19.901  -1.609  1.00 29.77  ? 214 GLU D OE2 1 
ATOM   8475  N  N   . LEU D 1 215 ? 32.580  23.861  1.116   1.00 27.22  ? 215 LEU D N   1 
ATOM   8476  C  CA  . LEU D 1 215 ? 32.452  25.162  0.495   1.00 28.91  ? 215 LEU D CA  1 
ATOM   8477  C  C   . LEU D 1 215 ? 32.463  24.936  -1.006  1.00 35.78  ? 215 LEU D C   1 
ATOM   8478  O  O   . LEU D 1 215 ? 33.228  24.066  -1.481  1.00 38.75  ? 215 LEU D O   1 
ATOM   8479  C  CB  . LEU D 1 215 ? 33.583  26.127  0.796   1.00 27.90  ? 215 LEU D CB  1 
ATOM   8480  C  CG  . LEU D 1 215 ? 33.781  26.658  2.212   1.00 33.87  ? 215 LEU D CG  1 
ATOM   8481  C  CD1 . LEU D 1 215 ? 34.845  27.778  2.237   1.00 35.08  ? 215 LEU D CD1 1 
ATOM   8482  C  CD2 . LEU D 1 215 ? 32.513  27.133  2.812   1.00 34.11  ? 215 LEU D CD2 1 
ATOM   8483  N  N   . SER D 1 216 ? 31.644  25.709  -1.759  1.00 43.03  ? 216 SER D N   1 
ATOM   8484  C  CA  . SER D 1 216 ? 31.548  25.438  -3.200  1.00 50.54  ? 216 SER D CA  1 
ATOM   8485  C  C   . SER D 1 216 ? 32.832  25.871  -3.903  1.00 49.64  ? 216 SER D C   1 
ATOM   8486  O  O   . SER D 1 216 ? 33.529  26.765  -3.384  1.00 40.47  ? 216 SER D O   1 
ATOM   8487  C  CB  . SER D 1 216 ? 30.376  26.107  -3.810  1.00 44.63  ? 216 SER D CB  1 
ATOM   8488  O  OG  . SER D 1 216 ? 30.513  27.491  -3.571  1.00 42.97  ? 216 SER D OG  1 
ATOM   8489  N  N   . ASP D 1 217 ? 33.093  25.261  -5.077  1.00 53.50  ? 217 ASP D N   1 
ATOM   8490  C  CA  . ASP D 1 217 ? 34.341  25.459  -5.820  1.00 56.51  ? 217 ASP D CA  1 
ATOM   8491  C  C   . ASP D 1 217 ? 34.578  26.933  -6.122  1.00 52.93  ? 217 ASP D C   1 
ATOM   8492  O  O   . ASP D 1 217 ? 35.718  27.376  -6.148  1.00 49.71  ? 217 ASP D O   1 
ATOM   8493  C  CB  . ASP D 1 217 ? 34.446  24.617  -7.075  1.00 54.93  ? 217 ASP D CB  1 
ATOM   8494  C  CG  . ASP D 1 217 ? 34.487  23.135  -6.764  1.00 76.00  ? 217 ASP D CG  1 
ATOM   8495  O  OD1 . ASP D 1 217 ? 35.310  22.752  -5.859  1.00 81.19  ? 217 ASP D OD1 1 
ATOM   8496  O  OD2 . ASP D 1 217 ? 33.683  22.397  -7.396  1.00 67.44  ? 217 ASP D OD2 1 
ATOM   8497  N  N   . ASP D 1 218 ? 33.511  27.711  -6.253  1.00 55.12  ? 218 ASP D N   1 
ATOM   8498  C  CA  . ASP D 1 218 ? 33.671  29.122  -6.543  1.00 66.15  ? 218 ASP D CA  1 
ATOM   8499  C  C   . ASP D 1 218 ? 34.093  29.905  -5.287  1.00 45.78  ? 218 ASP D C   1 
ATOM   8500  O  O   . ASP D 1 218 ? 34.538  31.032  -5.410  1.00 48.69  ? 218 ASP D O   1 
ATOM   8501  C  CB  . ASP D 1 218 ? 32.501  29.660  -7.371  1.00 73.35  ? 218 ASP D CB  1 
ATOM   8502  C  CG  . ASP D 1 218 ? 31.164  29.938  -6.668  1.00 83.39  ? 218 ASP D CG  1 
ATOM   8503  O  OD1 . ASP D 1 218 ? 30.960  29.534  -5.504  1.00 68.85  ? 218 ASP D OD1 1 
ATOM   8504  O  OD2 . ASP D 1 218 ? 30.314  30.597  -7.297  1.00 97.27  ? 218 ASP D OD2 1 
ATOM   8505  N  N   . VAL D 1 219 ? 34.020  29.380  -4.067  1.00 46.53  ? 219 VAL D N   1 
ATOM   8506  C  CA  . VAL D 1 219 ? 34.486  30.238  -2.961  1.00 55.11  ? 219 VAL D CA  1 
ATOM   8507  C  C   . VAL D 1 219 ? 35.632  29.602  -2.167  1.00 39.42  ? 219 VAL D C   1 
ATOM   8508  O  O   . VAL D 1 219 ? 36.300  30.295  -1.393  1.00 32.60  ? 219 VAL D O   1 
ATOM   8509  C  CB  . VAL D 1 219 ? 33.401  30.831  -2.015  1.00 56.96  ? 219 VAL D CB  1 
ATOM   8510  C  CG1 . VAL D 1 219 ? 32.694  32.032  -2.695  1.00 59.88  ? 219 VAL D CG1 1 
ATOM   8511  C  CG2 . VAL D 1 219 ? 32.420  29.772  -1.483  1.00 47.81  ? 219 VAL D CG2 1 
ATOM   8512  N  N   . LYS D 1 220 ? 35.896  28.325  -2.400  1.00 30.29  ? 220 LYS D N   1 
ATOM   8513  C  CA  . LYS D 1 220 ? 36.852  27.664  -1.539  1.00 32.03  ? 220 LYS D CA  1 
ATOM   8514  C  C   . LYS D 1 220 ? 38.250  28.138  -1.918  1.00 27.86  ? 220 LYS D C   1 
ATOM   8515  O  O   . LYS D 1 220 ? 38.682  27.969  -3.048  1.00 29.63  ? 220 LYS D O   1 
ATOM   8516  C  CB  . LYS D 1 220 ? 36.729  26.175  -1.838  1.00 33.82  ? 220 LYS D CB  1 
ATOM   8517  C  CG  . LYS D 1 220 ? 37.697  25.278  -1.091  1.00 33.27  ? 220 LYS D CG  1 
ATOM   8518  C  CD  . LYS D 1 220 ? 37.732  23.866  -1.660  1.00 34.71  ? 220 LYS D CD  1 
ATOM   8519  C  CE  . LYS D 1 220 ? 36.406  23.379  -1.967  1.00 37.16  ? 220 LYS D CE  1 
ATOM   8520  N  NZ  . LYS D 1 220 ? 36.520  21.983  -2.260  1.00 42.31  ? 220 LYS D NZ  1 
ATOM   8521  N  N   . PRO D 1 221 ? 39.035  28.698  -1.010  1.00 26.52  ? 221 PRO D N   1 
ATOM   8522  C  CA  . PRO D 1 221 ? 40.391  29.124  -1.340  1.00 25.88  ? 221 PRO D CA  1 
ATOM   8523  C  C   . PRO D 1 221 ? 41.324  27.980  -1.743  1.00 25.13  ? 221 PRO D C   1 
ATOM   8524  O  O   . PRO D 1 221 ? 41.182  26.860  -1.249  1.00 24.13  ? 221 PRO D O   1 
ATOM   8525  C  CB  . PRO D 1 221 ? 40.910  29.797  -0.062  1.00 28.61  ? 221 PRO D CB  1 
ATOM   8526  C  CG  . PRO D 1 221 ? 39.674  30.079  0.760   1.00 29.03  ? 221 PRO D CG  1 
ATOM   8527  C  CD  . PRO D 1 221 ? 38.638  29.045  0.345   1.00 29.76  ? 221 PRO D CD  1 
ATOM   8528  N  N   . ALA D 1 222 ? 42.278  28.294  -2.634  1.00 20.03  ? 222 ALA D N   1 
ATOM   8529  C  CA  . ALA D 1 222 ? 43.271  27.380  -3.133  1.00 19.68  ? 222 ALA D CA  1 
ATOM   8530  C  C   . ALA D 1 222 ? 44.203  26.936  -2.015  1.00 23.06  ? 222 ALA D C   1 
ATOM   8531  O  O   . ALA D 1 222 ? 44.801  25.868  -2.147  1.00 24.92  ? 222 ALA D O   1 
ATOM   8532  C  CB  . ALA D 1 222 ? 44.111  28.037  -4.173  1.00 20.80  ? 222 ALA D CB  1 
ATOM   8533  N  N   . ASP D 1 223 ? 44.368  27.764  -0.958  1.00 20.11  ? 223 ASP D N   1 
ATOM   8534  C  CA  . ASP D 1 223 ? 45.258  27.396  0.131   1.00 21.02  ? 223 ASP D CA  1 
ATOM   8535  C  C   . ASP D 1 223 ? 44.495  26.787  1.320   1.00 19.75  ? 223 ASP D C   1 
ATOM   8536  O  O   . ASP D 1 223 ? 45.044  26.654  2.388   1.00 22.76  ? 223 ASP D O   1 
ATOM   8537  C  CB  . ASP D 1 223 ? 46.225  28.519  0.448   1.00 18.24  ? 223 ASP D CB  1 
ATOM   8538  C  CG  . ASP D 1 223 ? 45.565  29.752  1.017   1.00 21.25  ? 223 ASP D CG  1 
ATOM   8539  O  OD1 . ASP D 1 223 ? 44.320  29.821  0.945   1.00 22.31  ? 223 ASP D OD1 1 
ATOM   8540  O  OD2 . ASP D 1 223 ? 46.285  30.662  1.520   1.00 21.45  ? 223 ASP D OD2 1 
ATOM   8541  N  N   . SER D 1 224 ? 43.252  26.415  1.136   1.00 19.06  ? 224 SER D N   1 
ATOM   8542  C  CA  . SER D 1 224 ? 42.498  25.726  2.159   1.00 21.62  ? 224 SER D CA  1 
ATOM   8543  C  C   . SER D 1 224 ? 42.944  24.265  2.172   1.00 21.28  ? 224 SER D C   1 
ATOM   8544  O  O   . SER D 1 224 ? 43.378  23.725  1.168   1.00 20.42  ? 224 SER D O   1 
ATOM   8545  C  CB  . SER D 1 224 ? 40.997  25.826  1.912   1.00 23.91  ? 224 SER D CB  1 
ATOM   8546  O  OG  . SER D 1 224 ? 40.639  25.071  0.753   1.00 24.51  ? 224 SER D OG  1 
ATOM   8547  N  N   . HIS D 1 225 ? 42.731  23.631  3.319   1.00 20.76  ? 225 HIS D N   1 
ATOM   8548  C  CA  . HIS D 1 225 ? 43.198  22.274  3.585   1.00 19.71  ? 225 HIS D CA  1 
ATOM   8549  C  C   . HIS D 1 225 ? 42.556  21.290  2.620   1.00 19.01  ? 225 HIS D C   1 
ATOM   8550  O  O   . HIS D 1 225 ? 43.204  20.388  2.082   1.00 21.61  ? 225 HIS D O   1 
ATOM   8551  C  CB  . HIS D 1 225 ? 42.940  21.960  5.062   1.00 17.61  ? 225 HIS D CB  1 
ATOM   8552  C  CG  . HIS D 1 225 ? 43.302  20.630  5.491   1.00 18.48  ? 225 HIS D CG  1 
ATOM   8553  N  ND1 . HIS D 1 225 ? 44.602  20.218  5.403   1.00 19.88  ? 225 HIS D ND1 1 
ATOM   8554  C  CD2 . HIS D 1 225 ? 42.603  19.591  5.964   1.00 20.80  ? 225 HIS D CD2 1 
ATOM   8555  C  CE1 . HIS D 1 225 ? 44.672  18.943  5.798   1.00 20.47  ? 225 HIS D CE1 1 
ATOM   8556  N  NE2 . HIS D 1 225 ? 43.479  18.549  6.183   1.00 19.37  ? 225 HIS D NE2 1 
ATOM   8557  N  N   . VAL D 1 226 ? 41.260  21.442  2.417   1.00 21.31  ? 226 VAL D N   1 
ATOM   8558  C  CA  . VAL D 1 226 ? 40.561  20.557  1.486   1.00 25.37  ? 226 VAL D CA  1 
ATOM   8559  C  C   . VAL D 1 226 ? 41.039  20.742  0.036   1.00 21.62  ? 226 VAL D C   1 
ATOM   8560  O  O   . VAL D 1 226 ? 41.117  19.816  -0.748  1.00 23.18  ? 226 VAL D O   1 
ATOM   8561  C  CB  . VAL D 1 226 ? 39.033  20.727  1.632   1.00 27.25  ? 226 VAL D CB  1 
ATOM   8562  C  CG1 . VAL D 1 226 ? 38.355  20.073  0.477   1.00 29.17  ? 226 VAL D CG1 1 
ATOM   8563  C  CG2 . VAL D 1 226 ? 38.505  20.053  2.886   1.00 28.96  ? 226 VAL D CG2 1 
ATOM   8564  N  N   . ALA D 1 227 ? 41.302  21.968  -0.358  1.00 19.52  ? 227 ALA D N   1 
ATOM   8565  C  CA  . ALA D 1 227 ? 41.783  22.201  -1.693  1.00 20.78  ? 227 ALA D CA  1 
ATOM   8566  C  C   . ALA D 1 227 ? 43.141  21.528  -1.866  1.00 22.65  ? 227 ALA D C   1 
ATOM   8567  O  O   . ALA D 1 227 ? 43.310  20.814  -2.842  1.00 26.48  ? 227 ALA D O   1 
ATOM   8568  C  CB  . ALA D 1 227 ? 41.856  23.694  -1.965  1.00 21.17  ? 227 ALA D CB  1 
ATOM   8569  N  N   . LEU D 1 228 ? 44.089  21.713  -0.929  1.00 20.38  ? 228 LEU D N   1 
ATOM   8570  C  CA  . LEU D 1 228 ? 45.405  21.165  -1.144  1.00 23.11  ? 228 LEU D CA  1 
ATOM   8571  C  C   . LEU D 1 228 ? 45.490  19.643  -0.962  1.00 28.52  ? 228 LEU D C   1 
ATOM   8572  O  O   . LEU D 1 228 ? 46.437  19.060  -1.478  1.00 27.26  ? 228 LEU D O   1 
ATOM   8573  C  CB  . LEU D 1 228 ? 46.424  21.844  -0.266  1.00 24.02  ? 228 LEU D CB  1 
ATOM   8574  C  CG  . LEU D 1 228 ? 46.788  23.247  -0.713  1.00 28.19  ? 228 LEU D CG  1 
ATOM   8575  C  CD1 . LEU D 1 228 ? 47.534  23.965  0.419   1.00 33.67  ? 228 LEU D CD1 1 
ATOM   8576  C  CD2 . LEU D 1 228 ? 47.586  23.202  -1.995  1.00 28.91  ? 228 LEU D CD2 1 
ATOM   8577  N  N   . THR D 1 229 ? 44.561  18.993  -0.237  1.00 26.76  ? 229 THR D N   1 
ATOM   8578  C  CA  . THR D 1 229 ? 44.654  17.559  -0.010  1.00 28.19  ? 229 THR D CA  1 
ATOM   8579  C  C   . THR D 1 229 ? 43.764  16.811  -0.995  1.00 31.24  ? 229 THR D C   1 
ATOM   8580  O  O   . THR D 1 229 ? 43.710  15.598  -0.896  1.00 33.95  ? 229 THR D O   1 
ATOM   8581  C  CB  . THR D 1 229 ? 44.318  17.192  1.437   1.00 27.38  ? 229 THR D CB  1 
ATOM   8582  O  OG1 . THR D 1 229 ? 43.036  17.716  1.780   1.00 22.14  ? 229 THR D OG1 1 
ATOM   8583  C  CG2 . THR D 1 229 ? 45.366  17.723  2.404   1.00 25.85  ? 229 THR D CG2 1 
ATOM   8584  N  N   . SER D 1 230 ? 43.127  17.502  -1.958  1.00 30.28  ? 230 SER D N   1 
ATOM   8585  C  CA  . SER D 1 230 ? 42.450  16.857  -3.086  1.00 33.23  ? 230 SER D CA  1 
ATOM   8586  C  C   . SER D 1 230 ? 43.409  16.676  -4.243  1.00 33.36  ? 230 SER D C   1 
ATOM   8587  O  O   . SER D 1 230 ? 43.955  17.642  -4.692  1.00 33.42  ? 230 SER D O   1 
ATOM   8588  C  CB  . SER D 1 230 ? 41.291  17.640  -3.514  1.00 32.61  ? 230 SER D CB  1 
ATOM   8589  O  OG  . SER D 1 230 ? 40.365  17.624  -2.409  1.00 42.97  ? 230 SER D OG  1 
ATOM   8590  N  N   . VAL D 1 231 ? 43.755  15.445  -4.614  1.00 34.10  ? 231 VAL D N   1 
ATOM   8591  C  CA  . VAL D 1 231 ? 44.685  15.250  -5.704  1.00 39.91  ? 231 VAL D CA  1 
ATOM   8592  C  C   . VAL D 1 231 ? 44.018  14.262  -6.654  1.00 40.55  ? 231 VAL D C   1 
ATOM   8593  O  O   . VAL D 1 231 ? 43.387  13.327  -6.173  1.00 34.91  ? 231 VAL D O   1 
ATOM   8594  C  CB  . VAL D 1 231 ? 46.082  14.811  -5.213  1.00 43.62  ? 231 VAL D CB  1 
ATOM   8595  C  CG1 . VAL D 1 231 ? 46.456  15.542  -3.954  1.00 52.06  ? 231 VAL D CG1 1 
ATOM   8596  C  CG2 . VAL D 1 231 ? 46.203  13.362  -4.858  1.00 46.55  ? 231 VAL D CG2 1 
ATOM   8597  N  N   . THR D 1 232 ? 44.127  14.485  -7.971  1.00 53.83  ? 232 THR D N   1 
ATOM   8598  C  CA  . THR D 1 232 ? 43.567  13.548  -8.956  1.00 59.11  ? 232 THR D CA  1 
ATOM   8599  C  C   . THR D 1 232 ? 44.726  12.798  -9.639  1.00 43.04  ? 232 THR D C   1 
ATOM   8600  O  O   . THR D 1 232 ? 45.823  13.291  -9.751  1.00 46.78  ? 232 THR D O   1 
ATOM   8601  C  CB  . THR D 1 232 ? 42.656  14.271  -9.958  1.00 53.19  ? 232 THR D CB  1 
ATOM   8602  O  OG1 . THR D 1 232 ? 43.729  14.993  -10.548 1.00 54.37  ? 232 THR D OG1 1 
ATOM   8603  C  CG2 . THR D 1 232 ? 41.613  15.247  -9.411  1.00 40.27  ? 232 THR D CG2 1 
ATOM   8604  N  N   . GLY D 1 233 ? 44.528  11.535  -9.986  1.00 50.86  ? 233 GLY D N   1 
ATOM   8605  C  CA  . GLY D 1 233 ? 45.571  10.727  -10.605 1.00 56.54  ? 233 GLY D CA  1 
ATOM   8606  C  C   . GLY D 1 233 ? 45.511  10.813  -12.128 1.00 62.56  ? 233 GLY D C   1 
ATOM   8607  O  O   . GLY D 1 233 ? 44.652  11.528  -12.667 1.00 60.40  ? 233 GLY D O   1 
ATOM   8608  N  N   . PRO D 1 234 ? 46.378  10.056  -12.855 1.00 80.73  ? 234 PRO D N   1 
ATOM   8609  C  CA  . PRO D 1 234 ? 46.383  10.098  -14.332 1.00 76.69  ? 234 PRO D CA  1 
ATOM   8610  C  C   . PRO D 1 234 ? 44.998  10.027  -14.989 1.00 72.35  ? 234 PRO D C   1 
ATOM   8611  O  O   . PRO D 1 234 ? 44.696  10.861  -15.831 1.00 73.10  ? 234 PRO D O   1 
ATOM   8612  C  CB  . PRO D 1 234 ? 47.336  8.951   -14.751 1.00 75.76  ? 234 PRO D CB  1 
ATOM   8613  C  CG  . PRO D 1 234 ? 48.232  8.729   -13.510 1.00 81.55  ? 234 PRO D CG  1 
ATOM   8614  C  CD  . PRO D 1 234 ? 47.382  9.127   -12.289 1.00 76.11  ? 234 PRO D CD  1 
ATOM   8615  N  N   . ASP D 1 235 ? 44.103  9.164   -14.486 1.00 67.73  ? 235 ASP D N   1 
ATOM   8616  C  CA  . ASP D 1 235 ? 42.740  9.016   -14.999 1.00 65.07  ? 235 ASP D CA  1 
ATOM   8617  C  C   . ASP D 1 235 ? 41.758  10.163  -14.752 1.00 60.49  ? 235 ASP D C   1 
ATOM   8618  O  O   . ASP D 1 235 ? 40.622  10.062  -15.204 1.00 70.65  ? 235 ASP D O   1 
ATOM   8619  C  CB  . ASP D 1 235 ? 42.004  7.866   -14.317 1.00 66.67  ? 235 ASP D CB  1 
ATOM   8620  C  CG  . ASP D 1 235 ? 42.560  7.498   -12.944 1.00 77.27  ? 235 ASP D CG  1 
ATOM   8621  O  OD1 . ASP D 1 235 ? 42.606  8.358   -11.997 1.00 72.70  ? 235 ASP D OD1 1 
ATOM   8622  O  OD2 . ASP D 1 235 ? 43.029  6.372   -12.846 1.00 65.10  ? 235 ASP D OD2 1 
ATOM   8623  N  N   . GLY D 1 236 ? 42.054  11.145  -13.898 1.00 61.19  ? 236 GLY D N   1 
ATOM   8624  C  CA  . GLY D 1 236 ? 40.989  12.047  -13.462 1.00 52.39  ? 236 GLY D CA  1 
ATOM   8625  C  C   . GLY D 1 236 ? 40.206  11.580  -12.228 1.00 61.44  ? 236 GLY D C   1 
ATOM   8626  O  O   . GLY D 1 236 ? 39.403  12.369  -11.751 1.00 56.64  ? 236 GLY D O   1 
ATOM   8627  N  N   . SER D 1 237 ? 40.416  10.350  -11.700 1.00 66.50  ? 237 SER D N   1 
ATOM   8628  C  CA  . SER D 1 237 ? 39.851  9.957   -10.402 1.00 64.48  ? 237 SER D CA  1 
ATOM   8629  C  C   . SER D 1 237 ? 40.640  10.568  -9.235  1.00 63.42  ? 237 SER D C   1 
ATOM   8630  O  O   . SER D 1 237 ? 41.878  10.668  -9.272  1.00 45.95  ? 237 SER D O   1 
ATOM   8631  C  CB  . SER D 1 237 ? 39.833  8.447   -10.201 1.00 70.61  ? 237 SER D CB  1 
ATOM   8632  O  OG  . SER D 1 237 ? 40.020  7.742   -11.408 1.00 87.53  ? 237 SER D OG  1 
ATOM   8633  N  N   . ASP D 1 238 ? 39.916  10.877  -8.153  1.00 57.95  ? 238 ASP D N   1 
ATOM   8634  C  CA  . ASP D 1 238 ? 40.501  11.179  -6.852  1.00 52.93  ? 238 ASP D CA  1 
ATOM   8635  C  C   . ASP D 1 238 ? 41.426  10.073  -6.319  1.00 48.84  ? 238 ASP D C   1 
ATOM   8636  O  O   . ASP D 1 238 ? 41.167  8.861   -6.402  1.00 46.33  ? 238 ASP D O   1 
ATOM   8637  C  CB  . ASP D 1 238 ? 39.382  11.577  -5.908  1.00 55.29  ? 238 ASP D CB  1 
ATOM   8638  C  CG  . ASP D 1 238 ? 38.793  12.908  -6.352  1.00 64.19  ? 238 ASP D CG  1 
ATOM   8639  O  OD1 . ASP D 1 238 ? 39.588  13.869  -6.485  1.00 70.58  ? 238 ASP D OD1 1 
ATOM   8640  O  OD2 . ASP D 1 238 ? 37.577  12.975  -6.631  1.00 65.61  ? 238 ASP D OD2 1 
ATOM   8641  N  N   . LEU D 1 239 ? 42.575  10.532  -5.818  1.00 40.22  ? 239 LEU D N   1 
ATOM   8642  C  CA  . LEU D 1 239 ? 43.480  9.712   -5.028  1.00 35.18  ? 239 LEU D CA  1 
ATOM   8643  C  C   . LEU D 1 239 ? 43.135  9.886   -3.558  1.00 24.99  ? 239 LEU D C   1 
ATOM   8644  O  O   . LEU D 1 239 ? 43.113  10.977  -3.070  1.00 26.98  ? 239 LEU D O   1 
ATOM   8645  C  CB  . LEU D 1 239 ? 44.920  10.149  -5.305  1.00 41.16  ? 239 LEU D CB  1 
ATOM   8646  C  CG  . LEU D 1 239 ? 45.483  9.814   -6.704  1.00 44.95  ? 239 LEU D CG  1 
ATOM   8647  C  CD1 . LEU D 1 239 ? 46.935  10.201  -6.698  1.00 41.02  ? 239 LEU D CD1 1 
ATOM   8648  C  CD2 . LEU D 1 239 ? 45.311  8.359   -7.207  1.00 36.84  ? 239 LEU D CD2 1 
ATOM   8649  N  N   . GLU D 1 240 ? 42.867  8.803   -2.873  1.00 23.92  ? 240 GLU D N   1 
ATOM   8650  C  CA  . GLU D 1 240 ? 42.273  8.847   -1.559  1.00 26.15  ? 240 GLU D CA  1 
ATOM   8651  C  C   . GLU D 1 240 ? 43.195  8.155   -0.554  1.00 27.42  ? 240 GLU D C   1 
ATOM   8652  O  O   . GLU D 1 240 ? 44.026  7.318   -0.907  1.00 24.29  ? 240 GLU D O   1 
ATOM   8653  C  CB  . GLU D 1 240 ? 40.929  8.158   -1.588  1.00 27.01  ? 240 GLU D CB  1 
ATOM   8654  C  CG  . GLU D 1 240 ? 40.014  8.731   -2.663  1.00 36.03  ? 240 GLU D CG  1 
ATOM   8655  C  CD  . GLU D 1 240 ? 38.610  8.169   -2.565  1.00 44.76  ? 240 GLU D CD  1 
ATOM   8656  O  OE1 . GLU D 1 240 ? 38.375  7.049   -3.044  1.00 52.54  ? 240 GLU D OE1 1 
ATOM   8657  O  OE2 . GLU D 1 240 ? 37.768  8.814   -1.955  1.00 43.54  ? 240 GLU D OE2 1 
ATOM   8658  N  N   . ILE D 1 241 ? 43.073  8.605   0.697   1.00 22.77  ? 241 ILE D N   1 
ATOM   8659  C  CA  . ILE D 1 241 ? 43.652  7.919   1.816   1.00 22.50  ? 241 ILE D CA  1 
ATOM   8660  C  C   . ILE D 1 241 ? 42.580  7.700   2.872   1.00 22.30  ? 241 ILE D C   1 
ATOM   8661  O  O   . ILE D 1 241 ? 41.509  8.315   2.854   1.00 23.56  ? 241 ILE D O   1 
ATOM   8662  C  CB  . ILE D 1 241 ? 44.860  8.680   2.398   1.00 24.14  ? 241 ILE D CB  1 
ATOM   8663  C  CG1 . ILE D 1 241 ? 44.439  9.963   3.111   1.00 22.09  ? 241 ILE D CG1 1 
ATOM   8664  C  CG2 . ILE D 1 241 ? 45.932  8.897   1.320   1.00 27.38  ? 241 ILE D CG2 1 
ATOM   8665  C  CD1 . ILE D 1 241 ? 45.605  10.753  3.642   1.00 23.57  ? 241 ILE D CD1 1 
ATOM   8666  N  N   . LEU D 1 242 ? 42.921  6.832   3.834   1.00 22.31  ? 242 LEU D N   1 
ATOM   8667  C  CA  . LEU D 1 242 ? 42.073  6.631   4.973   1.00 20.94  ? 242 LEU D CA  1 
ATOM   8668  C  C   . LEU D 1 242 ? 42.707  7.258   6.199   1.00 22.08  ? 242 LEU D C   1 
ATOM   8669  O  O   . LEU D 1 242 ? 43.776  6.844   6.565   1.00 20.81  ? 242 LEU D O   1 
ATOM   8670  C  CB  . LEU D 1 242 ? 41.888  5.148   5.168   1.00 20.15  ? 242 LEU D CB  1 
ATOM   8671  C  CG  . LEU D 1 242 ? 40.885  4.811   6.274   1.00 21.29  ? 242 LEU D CG  1 
ATOM   8672  C  CD1 . LEU D 1 242 ? 39.514  5.141   5.757   1.00 23.13  ? 242 LEU D CD1 1 
ATOM   8673  C  CD2 . LEU D 1 242 ? 40.950  3.329   6.559   1.00 23.44  ? 242 LEU D CD2 1 
ATOM   8674  N  N   . ARG D 1 243 ? 42.001  8.160   6.868   1.00 24.43  ? 243 ARG D N   1 
ATOM   8675  C  CA  . ARG D 1 243 ? 42.506  8.885   8.022   1.00 23.04  ? 243 ARG D CA  1 
ATOM   8676  C  C   . ARG D 1 243 ? 41.744  8.468   9.268   1.00 20.61  ? 243 ARG D C   1 
ATOM   8677  O  O   . ARG D 1 243 ? 40.600  8.086   9.171   1.00 19.88  ? 243 ARG D O   1 
ATOM   8678  C  CB  . ARG D 1 243 ? 42.351  10.405  7.939   1.00 21.63  ? 243 ARG D CB  1 
ATOM   8679  C  CG  . ARG D 1 243 ? 43.197  10.947  6.795   1.00 26.67  ? 243 ARG D CG  1 
ATOM   8680  C  CD  . ARG D 1 243 ? 42.792  12.362  6.520   1.00 27.34  ? 243 ARG D CD  1 
ATOM   8681  N  NE  . ARG D 1 243 ? 41.533  12.332  5.739   1.00 27.73  ? 243 ARG D NE  1 
ATOM   8682  C  CZ  . ARG D 1 243 ? 40.399  12.901  6.113   1.00 24.68  ? 243 ARG D CZ  1 
ATOM   8683  N  NH1 . ARG D 1 243 ? 40.391  13.710  7.163   1.00 22.91  ? 243 ARG D NH1 1 
ATOM   8684  N  NH2 . ARG D 1 243 ? 39.299  12.698  5.396   1.00 26.09  ? 243 ARG D NH2 1 
ATOM   8685  N  N   . ASP D 1 244 ? 42.404  8.543   10.430  1.00 22.82  ? 244 ASP D N   1 
ATOM   8686  C  CA  . ASP D 1 244 ? 41.734  8.339   11.691  1.00 24.92  ? 244 ASP D CA  1 
ATOM   8687  C  C   . ASP D 1 244 ? 42.377  9.246   12.739  1.00 21.72  ? 244 ASP D C   1 
ATOM   8688  O  O   . ASP D 1 244 ? 42.839  8.822   13.764  1.00 21.85  ? 244 ASP D O   1 
ATOM   8689  C  CB  . ASP D 1 244 ? 41.634  6.859   12.017  1.00 25.11  ? 244 ASP D CB  1 
ATOM   8690  C  CG  . ASP D 1 244 ? 40.538  6.554   13.020  1.00 31.79  ? 244 ASP D CG  1 
ATOM   8691  O  OD1 . ASP D 1 244 ? 39.747  7.469   13.328  1.00 36.13  ? 244 ASP D OD1 1 
ATOM   8692  O  OD2 . ASP D 1 244 ? 40.524  5.431   13.523  1.00 28.62  ? 244 ASP D OD2 1 
ATOM   8693  N  N   . ASN D 1 245 ? 42.342  10.512  12.469  1.00 18.90  ? 245 ASN D N   1 
ATOM   8694  C  CA  . ASN D 1 245 ? 42.927  11.493  13.323  1.00 21.98  ? 245 ASN D CA  1 
ATOM   8695  C  C   . ASN D 1 245 ? 42.234  11.485  14.688  1.00 26.14  ? 245 ASN D C   1 
ATOM   8696  O  O   . ASN D 1 245 ? 41.014  11.412  14.759  1.00 28.16  ? 245 ASN D O   1 
ATOM   8697  C  CB  . ASN D 1 245 ? 42.717  12.891  12.735  1.00 23.02  ? 245 ASN D CB  1 
ATOM   8698  C  CG  . ASN D 1 245 ? 43.411  13.076  11.413  1.00 24.89  ? 245 ASN D CG  1 
ATOM   8699  O  OD1 . ASN D 1 245 ? 44.195  12.223  10.965  1.00 23.99  ? 245 ASN D OD1 1 
ATOM   8700  N  ND2 . ASN D 1 245 ? 43.087  14.187  10.784  1.00 29.62  ? 245 ASN D ND2 1 
ATOM   8701  N  N   . MET D 1 246 ? 43.036  11.656  15.755  1.00 23.46  ? 246 MET D N   1 
ATOM   8702  C  CA  . MET D 1 246 ? 42.565  11.655  17.121  1.00 22.90  ? 246 MET D CA  1 
ATOM   8703  C  C   . MET D 1 246 ? 43.094  12.861  17.866  1.00 22.44  ? 246 MET D C   1 
ATOM   8704  O  O   . MET D 1 246 ? 44.291  13.097  17.939  1.00 22.38  ? 246 MET D O   1 
ATOM   8705  C  CB  . MET D 1 246 ? 43.016  10.422  17.886  1.00 22.10  ? 246 MET D CB  1 
ATOM   8706  C  CG  . MET D 1 246 ? 42.392  9.178   17.353  1.00 25.95  ? 246 MET D CG  1 
ATOM   8707  S  SD  . MET D 1 246 ? 40.602  9.054   17.485  1.00 27.83  ? 246 MET D SD  1 
ATOM   8708  C  CE  . MET D 1 246 ? 40.404  8.670   19.233  1.00 25.88  ? 246 MET D CE  1 
ATOM   8709  N  N   . PRO D 1 247 ? 42.199  13.613  18.533  1.00 23.13  ? 247 PRO D N   1 
ATOM   8710  C  CA  . PRO D 1 247 ? 42.584  14.629  19.501  1.00 20.67  ? 247 PRO D CA  1 
ATOM   8711  C  C   . PRO D 1 247 ? 43.315  14.030  20.693  1.00 19.60  ? 247 PRO D C   1 
ATOM   8712  O  O   . PRO D 1 247 ? 43.074  12.893  21.082  1.00 18.51  ? 247 PRO D O   1 
ATOM   8713  C  CB  . PRO D 1 247 ? 41.258  15.205  19.963  1.00 19.64  ? 247 PRO D CB  1 
ATOM   8714  C  CG  . PRO D 1 247 ? 40.305  14.821  18.896  1.00 21.85  ? 247 PRO D CG  1 
ATOM   8715  C  CD  . PRO D 1 247 ? 40.757  13.476  18.432  1.00 21.76  ? 247 PRO D CD  1 
ATOM   8716  N  N   . PHE D 1 248 ? 44.176  14.849  21.266  1.00 18.98  ? 248 PHE D N   1 
ATOM   8717  C  CA  . PHE D 1 248 ? 44.800  14.486  22.507  1.00 21.48  ? 248 PHE D CA  1 
ATOM   8718  C  C   . PHE D 1 248 ? 45.186  15.780  23.169  1.00 20.58  ? 248 PHE D C   1 
ATOM   8719  O  O   . PHE D 1 248 ? 45.229  16.837  22.554  1.00 20.31  ? 248 PHE D O   1 
ATOM   8720  C  CB  . PHE D 1 248 ? 46.034  13.569  22.327  1.00 24.89  ? 248 PHE D CB  1 
ATOM   8721  C  CG  . PHE D 1 248 ? 47.211  14.272  21.653  1.00 24.63  ? 248 PHE D CG  1 
ATOM   8722  C  CD1 . PHE D 1 248 ? 47.297  14.341  20.270  1.00 22.49  ? 248 PHE D CD1 1 
ATOM   8723  C  CD2 . PHE D 1 248 ? 48.198  14.913  22.406  1.00 22.45  ? 248 PHE D CD2 1 
ATOM   8724  C  CE1 . PHE D 1 248 ? 48.343  15.015  19.654  1.00 22.25  ? 248 PHE D CE1 1 
ATOM   8725  C  CE2 . PHE D 1 248 ? 49.208  15.630  21.789  1.00 23.03  ? 248 PHE D CE2 1 
ATOM   8726  C  CZ  . PHE D 1 248 ? 49.289  15.656  20.416  1.00 23.05  ? 248 PHE D CZ  1 
ATOM   8727  N  N   . GLY D 1 249 ? 45.505  15.683  24.448  1.00 21.15  ? 249 GLY D N   1 
ATOM   8728  C  CA  . GLY D 1 249 ? 45.967  16.880  25.084  1.00 23.42  ? 249 GLY D CA  1 
ATOM   8729  C  C   . GLY D 1 249 ? 46.186  16.783  26.590  1.00 20.63  ? 249 GLY D C   1 
ATOM   8730  O  O   . GLY D 1 249 ? 45.894  15.802  27.240  1.00 19.99  ? 249 GLY D O   1 
ATOM   8731  N  N   . SER D 1 250 ? 46.642  17.916  27.088  1.00 21.49  ? 250 SER D N   1 
ATOM   8732  C  CA  . SER D 1 250 ? 46.900  18.096  28.484  1.00 25.65  ? 250 SER D CA  1 
ATOM   8733  C  C   . SER D 1 250 ? 46.576  19.552  28.848  1.00 26.02  ? 250 SER D C   1 
ATOM   8734  O  O   . SER D 1 250 ? 47.096  20.471  28.272  1.00 28.78  ? 250 SER D O   1 
ATOM   8735  C  CB  . SER D 1 250 ? 48.319  17.641  28.765  1.00 28.34  ? 250 SER D CB  1 
ATOM   8736  O  OG  . SER D 1 250 ? 48.729  18.293  29.957  1.00 35.40  ? 250 SER D OG  1 
ATOM   8737  N  N   . VAL D 1 251 ? 45.681  19.795  29.786  1.00 23.47  ? 251 VAL D N   1 
ATOM   8738  C  CA  . VAL D 1 251 ? 45.129  21.127  29.931  1.00 24.69  ? 251 VAL D CA  1 
ATOM   8739  C  C   . VAL D 1 251 ? 46.112  21.949  30.724  1.00 25.09  ? 251 VAL D C   1 
ATOM   8740  O  O   . VAL D 1 251 ? 46.258  23.139  30.498  1.00 28.13  ? 251 VAL D O   1 
ATOM   8741  C  CB  . VAL D 1 251 ? 43.775  20.884  30.626  1.00 35.65  ? 251 VAL D CB  1 
ATOM   8742  C  CG1 . VAL D 1 251 ? 43.523  21.802  31.795  1.00 40.36  ? 251 VAL D CG1 1 
ATOM   8743  C  CG2 . VAL D 1 251 ? 42.634  20.895  29.628  1.00 36.90  ? 251 VAL D CG2 1 
ATOM   8744  N  N   . GLY D 1 252 ? 46.829  21.277  31.622  1.00 27.79  ? 252 GLY D N   1 
ATOM   8745  C  CA  . GLY D 1 252 ? 47.736  21.993  32.508  1.00 32.87  ? 252 GLY D CA  1 
ATOM   8746  C  C   . GLY D 1 252 ? 48.948  22.490  31.743  1.00 33.62  ? 252 GLY D C   1 
ATOM   8747  O  O   . GLY D 1 252 ? 49.386  23.600  31.967  1.00 35.47  ? 252 GLY D O   1 
ATOM   8748  N  N   . ARG D 1 253 ? 49.441  21.671  30.811  1.00 38.21  ? 253 ARG D N   1 
ATOM   8749  C  CA  . ARG D 1 253 ? 50.555  22.071  29.966  1.00 40.61  ? 253 ARG D CA  1 
ATOM   8750  C  C   . ARG D 1 253 ? 50.124  22.876  28.722  1.00 39.06  ? 253 ARG D C   1 
ATOM   8751  O  O   . ARG D 1 253 ? 50.948  23.210  27.917  1.00 35.05  ? 253 ARG D O   1 
ATOM   8752  C  CB  . ARG D 1 253 ? 51.346  20.830  29.578  1.00 38.58  ? 253 ARG D CB  1 
ATOM   8753  C  CG  . ARG D 1 253 ? 51.987  20.145  30.780  1.00 48.11  ? 253 ARG D CG  1 
ATOM   8754  C  CD  . ARG D 1 253 ? 53.332  19.472  30.465  1.00 63.39  ? 253 ARG D CD  1 
ATOM   8755  N  NE  . ARG D 1 253 ? 53.125  18.657  29.259  1.00 80.35  ? 253 ARG D NE  1 
ATOM   8756  C  CZ  . ARG D 1 253 ? 52.232  17.646  29.119  1.00 83.74  ? 253 ARG D CZ  1 
ATOM   8757  N  NH1 . ARG D 1 253 ? 51.713  16.994  30.144  1.00 78.35  ? 253 ARG D NH1 1 
ATOM   8758  N  NH2 . ARG D 1 253 ? 51.890  17.223  27.915  1.00 82.16  ? 253 ARG D NH2 1 
ATOM   8759  N  N   . GLU D 1 254 ? 48.845  23.233  28.567  1.00 33.21  ? 254 GLU D N   1 
ATOM   8760  C  CA  . GLU D 1 254 ? 48.327  23.859  27.374  1.00 32.30  ? 254 GLU D CA  1 
ATOM   8761  C  C   . GLU D 1 254 ? 48.766  23.134  26.121  1.00 28.87  ? 254 GLU D C   1 
ATOM   8762  O  O   . GLU D 1 254 ? 49.131  23.778  25.180  1.00 37.49  ? 254 GLU D O   1 
ATOM   8763  C  CB  . GLU D 1 254 ? 48.811  25.292  27.310  1.00 37.34  ? 254 GLU D CB  1 
ATOM   8764  C  CG  . GLU D 1 254 ? 48.100  26.157  28.340  1.00 53.48  ? 254 GLU D CG  1 
ATOM   8765  C  CD  . GLU D 1 254 ? 48.710  27.558  28.330  1.00 56.50  ? 254 GLU D CD  1 
ATOM   8766  O  OE1 . GLU D 1 254 ? 48.565  28.288  27.314  1.00 47.62  ? 254 GLU D OE1 1 
ATOM   8767  O  OE2 . GLU D 1 254 ? 49.440  27.854  29.297  1.00 52.00  ? 254 GLU D OE2 1 
ATOM   8768  N  N   . GLU D 1 255 ? 48.699  21.810  26.093  1.00 31.80  ? 255 GLU D N   1 
ATOM   8769  C  CA  . GLU D 1 255 ? 48.829  21.007  24.898  1.00 33.34  ? 255 GLU D CA  1 
ATOM   8770  C  C   . GLU D 1 255 ? 47.480  20.616  24.335  1.00 25.92  ? 255 GLU D C   1 
ATOM   8771  O  O   . GLU D 1 255 ? 46.723  19.919  24.977  1.00 24.04  ? 255 GLU D O   1 
ATOM   8772  C  CB  . GLU D 1 255 ? 49.603  19.726  25.151  1.00 38.36  ? 255 GLU D CB  1 
ATOM   8773  C  CG  . GLU D 1 255 ? 51.083  20.022  25.321  1.00 52.34  ? 255 GLU D CG  1 
ATOM   8774  C  CD  . GLU D 1 255 ? 51.918  18.767  25.330  1.00 53.70  ? 255 GLU D CD  1 
ATOM   8775  O  OE1 . GLU D 1 255 ? 51.484  17.589  25.112  1.00 50.71  ? 255 GLU D OE1 1 
ATOM   8776  O  OE2 . GLU D 1 255 ? 53.072  19.090  25.594  1.00 56.50  ? 255 GLU D OE2 1 
ATOM   8777  N  N   . PHE D 1 256 ? 47.201  21.073  23.121  1.00 23.97  ? 256 PHE D N   1 
ATOM   8778  C  CA  . PHE D 1 256 ? 46.025  20.650  22.406  1.00 25.26  ? 256 PHE D CA  1 
ATOM   8779  C  C   . PHE D 1 256 ? 46.488  20.149  21.048  1.00 23.90  ? 256 PHE D C   1 
ATOM   8780  O  O   . PHE D 1 256 ? 47.075  20.934  20.339  1.00 22.99  ? 256 PHE D O   1 
ATOM   8781  C  CB  . PHE D 1 256 ? 45.011  21.794  22.265  1.00 28.45  ? 256 PHE D CB  1 
ATOM   8782  C  CG  . PHE D 1 256 ? 44.703  22.456  23.595  1.00 31.82  ? 256 PHE D CG  1 
ATOM   8783  C  CD1 . PHE D 1 256 ? 43.748  21.905  24.428  1.00 32.48  ? 256 PHE D CD1 1 
ATOM   8784  C  CD2 . PHE D 1 256 ? 45.382  23.619  23.991  1.00 28.58  ? 256 PHE D CD2 1 
ATOM   8785  C  CE1 . PHE D 1 256 ? 43.505  22.492  25.645  1.00 30.93  ? 256 PHE D CE1 1 
ATOM   8786  C  CE2 . PHE D 1 256 ? 45.118  24.180  25.195  1.00 27.62  ? 256 PHE D CE2 1 
ATOM   8787  C  CZ  . PHE D 1 256 ? 44.189  23.620  26.016  1.00 27.63  ? 256 PHE D CZ  1 
ATOM   8788  N  N   . GLY D 1 257 ? 46.156  18.907  20.697  1.00 20.33  ? 257 GLY D N   1 
ATOM   8789  C  CA  . GLY D 1 257 ? 46.850  18.234  19.619  1.00 22.48  ? 257 GLY D CA  1 
ATOM   8790  C  C   . GLY D 1 257 ? 45.897  17.445  18.731  1.00 19.82  ? 257 GLY D C   1 
ATOM   8791  O  O   . GLY D 1 257 ? 44.758  17.169  19.115  1.00 22.58  ? 257 GLY D O   1 
ATOM   8792  N  N   . THR D 1 258 ? 46.377  17.149  17.534  1.00 19.36  ? 258 THR D N   1 
ATOM   8793  C  CA  . THR D 1 258 ? 45.745  16.231  16.638  1.00 20.38  ? 258 THR D CA  1 
ATOM   8794  C  C   . THR D 1 258 ? 46.808  15.212  16.304  1.00 20.67  ? 258 THR D C   1 
ATOM   8795  O  O   . THR D 1 258 ? 47.852  15.597  15.836  1.00 20.66  ? 258 THR D O   1 
ATOM   8796  C  CB  . THR D 1 258 ? 45.148  16.903  15.380  1.00 24.77  ? 258 THR D CB  1 
ATOM   8797  O  OG1 . THR D 1 258 ? 44.001  17.710  15.694  1.00 30.84  ? 258 THR D OG1 1 
ATOM   8798  C  CG2 . THR D 1 258 ? 44.738  15.833  14.357  1.00 24.80  ? 258 THR D CG2 1 
ATOM   8799  N  N   . TYR D 1 259 ? 46.537  13.928  16.530  1.00 17.99  ? 259 TYR D N   1 
ATOM   8800  C  CA  . TYR D 1 259 ? 47.428  12.881  16.097  1.00 18.65  ? 259 TYR D CA  1 
ATOM   8801  C  C   . TYR D 1 259 ? 46.920  12.393  14.736  1.00 19.26  ? 259 TYR D C   1 
ATOM   8802  O  O   . TYR D 1 259 ? 45.874  11.786  14.620  1.00 16.57  ? 259 TYR D O   1 
ATOM   8803  C  CB  . TYR D 1 259 ? 47.598  11.767  17.141  1.00 19.42  ? 259 TYR D CB  1 
ATOM   8804  C  CG  . TYR D 1 259 ? 48.840  10.914  16.960  1.00 19.88  ? 259 TYR D CG  1 
ATOM   8805  C  CD1 . TYR D 1 259 ? 48.858  9.880   16.023  1.00 22.19  ? 259 TYR D CD1 1 
ATOM   8806  C  CD2 . TYR D 1 259 ? 49.993  11.122  17.696  1.00 25.07  ? 259 TYR D CD2 1 
ATOM   8807  C  CE1 . TYR D 1 259 ? 49.983  9.102   15.803  1.00 20.34  ? 259 TYR D CE1 1 
ATOM   8808  C  CE2 . TYR D 1 259 ? 51.133  10.343  17.489  1.00 25.29  ? 259 TYR D CE2 1 
ATOM   8809  C  CZ  . TYR D 1 259 ? 51.107  9.323   16.560  1.00 22.05  ? 259 TYR D CZ  1 
ATOM   8810  O  OH  . TYR D 1 259 ? 52.151  8.532   16.318  1.00 26.12  ? 259 TYR D OH  1 
ATOM   8811  N  N   . PHE D 1 260 ? 47.690  12.696  13.688  1.00 20.12  ? 260 PHE D N   1 
ATOM   8812  C  CA  . PHE D 1 260 ? 47.387  12.346  12.322  1.00 21.67  ? 260 PHE D CA  1 
ATOM   8813  C  C   . PHE D 1 260 ? 47.879  10.938  12.035  1.00 21.08  ? 260 PHE D C   1 
ATOM   8814  O  O   . PHE D 1 260 ? 49.048  10.647  12.274  1.00 21.31  ? 260 PHE D O   1 
ATOM   8815  C  CB  . PHE D 1 260 ? 48.059  13.331  11.363  1.00 20.23  ? 260 PHE D CB  1 
ATOM   8816  C  CG  . PHE D 1 260 ? 47.928  12.881  9.929   1.00 19.80  ? 260 PHE D CG  1 
ATOM   8817  C  CD1 . PHE D 1 260 ? 46.742  13.067  9.245   1.00 22.41  ? 260 PHE D CD1 1 
ATOM   8818  C  CD2 . PHE D 1 260 ? 48.945  12.222  9.307   1.00 20.46  ? 260 PHE D CD2 1 
ATOM   8819  C  CE1 . PHE D 1 260 ? 46.581  12.628  7.944   1.00 23.47  ? 260 PHE D CE1 1 
ATOM   8820  C  CE2 . PHE D 1 260 ? 48.741  11.713  8.038   1.00 23.87  ? 260 PHE D CE2 1 
ATOM   8821  C  CZ  . PHE D 1 260 ? 47.576  11.953  7.353   1.00 22.16  ? 260 PHE D CZ  1 
ATOM   8822  N  N   . ILE D 1 261 ? 46.993  10.097  11.490  1.00 20.19  ? 261 ILE D N   1 
ATOM   8823  C  CA  . ILE D 1 261 ? 47.392  8.830   10.906  1.00 19.58  ? 261 ILE D CA  1 
ATOM   8824  C  C   . ILE D 1 261 ? 46.616  8.648   9.609   1.00 17.66  ? 261 ILE D C   1 
ATOM   8825  O  O   . ILE D 1 261 ? 45.447  8.833   9.571   1.00 16.05  ? 261 ILE D O   1 
ATOM   8826  C  CB  . ILE D 1 261 ? 47.264  7.613   11.856  1.00 21.38  ? 261 ILE D CB  1 
ATOM   8827  C  CG1 . ILE D 1 261 ? 47.867  6.367   11.237  1.00 23.35  ? 261 ILE D CG1 1 
ATOM   8828  C  CG2 . ILE D 1 261 ? 45.821  7.332   12.249  1.00 20.39  ? 261 ILE D CG2 1 
ATOM   8829  C  CD1 . ILE D 1 261 ? 48.158  5.248   12.237  1.00 26.63  ? 261 ILE D CD1 1 
ATOM   8830  N  N   . GLY D 1 262 ? 47.359  8.397   8.533   1.00 19.93  ? 262 GLY D N   1 
ATOM   8831  C  CA  . GLY D 1 262 ? 46.796  8.152   7.248   1.00 19.40  ? 262 GLY D CA  1 
ATOM   8832  C  C   . GLY D 1 262 ? 47.371  6.893   6.652   1.00 18.90  ? 262 GLY D C   1 
ATOM   8833  O  O   . GLY D 1 262 ? 48.593  6.730   6.586   1.00 25.16  ? 262 GLY D O   1 
ATOM   8834  N  N   . TYR D 1 263 ? 46.472  6.041   6.160   1.00 18.91  ? 263 TYR D N   1 
ATOM   8835  C  CA  . TYR D 1 263 ? 46.799  4.801   5.470   1.00 20.48  ? 263 TYR D CA  1 
ATOM   8836  C  C   . TYR D 1 263 ? 46.513  4.909   3.969   1.00 22.26  ? 263 TYR D C   1 
ATOM   8837  O  O   . TYR D 1 263 ? 45.499  5.470   3.575   1.00 23.13  ? 263 TYR D O   1 
ATOM   8838  C  CB  . TYR D 1 263 ? 45.927  3.687   6.028   1.00 20.13  ? 263 TYR D CB  1 
ATOM   8839  C  CG  . TYR D 1 263 ? 46.234  3.264   7.446   1.00 18.59  ? 263 TYR D CG  1 
ATOM   8840  C  CD1 . TYR D 1 263 ? 47.153  2.267   7.690   1.00 21.93  ? 263 TYR D CD1 1 
ATOM   8841  C  CD2 . TYR D 1 263 ? 45.511  3.754   8.504   1.00 17.80  ? 263 TYR D CD2 1 
ATOM   8842  C  CE1 . TYR D 1 263 ? 47.374  1.780   8.969   1.00 23.97  ? 263 TYR D CE1 1 
ATOM   8843  C  CE2 . TYR D 1 263 ? 45.738  3.314   9.793   1.00 20.09  ? 263 TYR D CE2 1 
ATOM   8844  C  CZ  . TYR D 1 263 ? 46.667  2.304   10.037  1.00 25.59  ? 263 TYR D CZ  1 
ATOM   8845  O  OH  . TYR D 1 263 ? 46.974  1.896   11.316  1.00 23.41  ? 263 TYR D OH  1 
ATOM   8846  N  N   . ALA D 1 264 ? 47.390  4.345   3.147   1.00 20.15  ? 264 ALA D N   1 
ATOM   8847  C  CA  . ALA D 1 264 ? 47.272  4.332   1.691   1.00 23.59  ? 264 ALA D CA  1 
ATOM   8848  C  C   . ALA D 1 264 ? 48.007  3.103   1.143   1.00 25.47  ? 264 ALA D C   1 
ATOM   8849  O  O   . ALA D 1 264 ? 48.974  2.647   1.767   1.00 23.62  ? 264 ALA D O   1 
ATOM   8850  C  CB  . ALA D 1 264 ? 47.909  5.584   1.139   1.00 20.66  ? 264 ALA D CB  1 
ATOM   8851  N  N   . ARG D 1 265 ? 47.608  2.637   -0.053  1.00 23.90  ? 265 ARG D N   1 
ATOM   8852  C  CA  . ARG D 1 265 ? 48.232  1.479   -0.681  1.00 26.88  ? 265 ARG D CA  1 
ATOM   8853  C  C   . ARG D 1 265 ? 49.653  1.779   -1.124  1.00 25.80  ? 265 ARG D C   1 
ATOM   8854  O  O   . ARG D 1 265 ? 50.443  0.856   -1.329  1.00 29.26  ? 265 ARG D O   1 
ATOM   8855  C  CB  . ARG D 1 265 ? 47.465  0.849   -1.856  1.00 30.15  ? 265 ARG D CB  1 
ATOM   8856  C  CG  . ARG D 1 265 ? 47.474  1.568   -3.176  1.00 42.29  ? 265 ARG D CG  1 
ATOM   8857  C  CD  . ARG D 1 265 ? 46.432  1.085   -4.214  1.00 48.35  ? 265 ARG D CD  1 
ATOM   8858  N  NE  . ARG D 1 265 ? 46.745  -0.291  -4.585  1.00 50.31  ? 265 ARG D NE  1 
ATOM   8859  C  CZ  . ARG D 1 265 ? 45.922  -1.195  -5.128  1.00 51.55  ? 265 ARG D CZ  1 
ATOM   8860  N  NH1 . ARG D 1 265 ? 44.629  -0.977  -5.184  1.00 47.16  ? 265 ARG D NH1 1 
ATOM   8861  N  NH2 . ARG D 1 265 ? 46.368  -2.381  -5.526  1.00 51.11  ? 265 ARG D NH2 1 
ATOM   8862  N  N   . THR D 1 266 ? 49.989  3.053   -1.333  1.00 22.92  ? 266 THR D N   1 
ATOM   8863  C  CA  . THR D 1 266 ? 51.374  3.411   -1.637  1.00 24.76  ? 266 THR D CA  1 
ATOM   8864  C  C   . THR D 1 266 ? 51.646  4.730   -0.942  1.00 27.84  ? 266 THR D C   1 
ATOM   8865  O  O   . THR D 1 266 ? 50.804  5.631   -0.936  1.00 33.11  ? 266 THR D O   1 
ATOM   8866  C  CB  . THR D 1 266 ? 51.641  3.539   -3.148  1.00 25.74  ? 266 THR D CB  1 
ATOM   8867  O  OG1 . THR D 1 266 ? 52.872  4.259   -3.310  1.00 32.46  ? 266 THR D OG1 1 
ATOM   8868  C  CG2 . THR D 1 266 ? 50.573  4.362   -3.838  1.00 24.72  ? 266 THR D CG2 1 
ATOM   8869  N  N   . PRO D 1 267 ? 52.851  4.942   -0.405  1.00 25.73  ? 267 PRO D N   1 
ATOM   8870  C  CA  . PRO D 1 267 ? 53.093  6.205   0.278   1.00 25.30  ? 267 PRO D CA  1 
ATOM   8871  C  C   . PRO D 1 267 ? 53.147  7.415   -0.635  1.00 25.93  ? 267 PRO D C   1 
ATOM   8872  O  O   . PRO D 1 267 ? 53.036  8.503   -0.083  1.00 26.86  ? 267 PRO D O   1 
ATOM   8873  C  CB  . PRO D 1 267 ? 54.360  5.935   1.071   1.00 24.32  ? 267 PRO D CB  1 
ATOM   8874  C  CG  . PRO D 1 267 ? 55.038  4.829   0.303   1.00 26.61  ? 267 PRO D CG  1 
ATOM   8875  C  CD  . PRO D 1 267 ? 53.962  3.995   -0.364  1.00 25.28  ? 267 PRO D CD  1 
ATOM   8876  N  N   . GLU D 1 268 ? 53.258  7.206   -1.967  1.00 26.27  ? 268 GLU D N   1 
ATOM   8877  C  CA  . GLU D 1 268 ? 53.358  8.285   -2.965  1.00 28.87  ? 268 GLU D CA  1 
ATOM   8878  C  C   . GLU D 1 268 ? 52.147  9.237   -2.790  1.00 24.63  ? 268 GLU D C   1 
ATOM   8879  O  O   . GLU D 1 268 ? 52.252  10.471  -2.888  1.00 21.85  ? 268 GLU D O   1 
ATOM   8880  C  CB  . GLU D 1 268 ? 53.617  7.850   -4.446  1.00 32.69  ? 268 GLU D CB  1 
ATOM   8881  C  CG  . GLU D 1 268 ? 54.958  7.198   -4.874  1.00 33.59  ? 268 GLU D CG  1 
ATOM   8882  N  N   . VAL D 1 269 ? 50.955  8.694   -2.534  1.00 25.70  ? 269 VAL D N   1 
ATOM   8883  C  CA  . VAL D 1 269 ? 49.728  9.493   -2.428  1.00 24.37  ? 269 VAL D CA  1 
ATOM   8884  C  C   . VAL D 1 269 ? 49.824  10.409  -1.219  1.00 23.63  ? 269 VAL D C   1 
ATOM   8885  O  O   . VAL D 1 269 ? 49.640  11.611  -1.337  1.00 21.29  ? 269 VAL D O   1 
ATOM   8886  C  CB  . VAL D 1 269 ? 48.495  8.580   -2.291  1.00 30.41  ? 269 VAL D CB  1 
ATOM   8887  C  CG1 . VAL D 1 269 ? 47.238  9.397   -2.069  1.00 29.13  ? 269 VAL D CG1 1 
ATOM   8888  C  CG2 . VAL D 1 269 ? 48.365  7.591   -3.467  1.00 31.39  ? 269 VAL D CG2 1 
ATOM   8889  N  N   . THR D 1 270 ? 50.121  9.825   -0.052  1.00 24.39  ? 270 THR D N   1 
ATOM   8890  C  CA  . THR D 1 270 ? 50.275  10.593  1.184   1.00 27.27  ? 270 THR D CA  1 
ATOM   8891  C  C   . THR D 1 270 ? 51.398  11.638  1.078   1.00 22.53  ? 270 THR D C   1 
ATOM   8892  O  O   . THR D 1 270 ? 51.246  12.767  1.532   1.00 17.91  ? 270 THR D O   1 
ATOM   8893  C  CB  . THR D 1 270 ? 50.523  9.646   2.363   1.00 26.34  ? 270 THR D CB  1 
ATOM   8894  O  OG1 . THR D 1 270 ? 49.571  8.590   2.259   1.00 24.29  ? 270 THR D OG1 1 
ATOM   8895  C  CG2 . THR D 1 270 ? 50.394  10.368  3.687   1.00 24.07  ? 270 THR D CG2 1 
ATOM   8896  N  N   . GLU D 1 271 ? 52.519  11.256  0.457   1.00 24.61  ? 271 GLU D N   1 
ATOM   8897  C  CA  . GLU D 1 271 ? 53.668  12.137  0.258   1.00 24.62  ? 271 GLU D CA  1 
ATOM   8898  C  C   . GLU D 1 271 ? 53.337  13.297  -0.679  1.00 20.55  ? 271 GLU D C   1 
ATOM   8899  O  O   . GLU D 1 271 ? 53.836  14.378  -0.498  1.00 22.33  ? 271 GLU D O   1 
ATOM   8900  C  CB  . GLU D 1 271 ? 54.874  11.316  -0.210  1.00 22.28  ? 271 GLU D CB  1 
ATOM   8901  C  CG  . GLU D 1 271 ? 55.483  10.585  0.972   1.00 28.43  ? 271 GLU D CG  1 
ATOM   8902  C  CD  . GLU D 1 271 ? 56.540  9.551   0.697   1.00 29.95  ? 271 GLU D CD  1 
ATOM   8903  O  OE1 . GLU D 1 271 ? 56.586  9.232   -0.483  1.00 28.27  ? 271 GLU D OE1 1 
ATOM   8904  O  OE2 . GLU D 1 271 ? 57.176  9.091   1.681   1.00 29.80  ? 271 GLU D OE2 1 
ATOM   8905  N  N   . THR D 1 272 ? 52.486  13.077  -1.656  1.00 21.62  ? 272 THR D N   1 
ATOM   8906  C  CA  . THR D 1 272 ? 52.099  14.148  -2.565  1.00 23.32  ? 272 THR D CA  1 
ATOM   8907  C  C   . THR D 1 272 ? 51.314  15.207  -1.799  1.00 21.97  ? 272 THR D C   1 
ATOM   8908  O  O   . THR D 1 272 ? 51.533  16.421  -1.976  1.00 22.80  ? 272 THR D O   1 
ATOM   8909  C  CB  . THR D 1 272 ? 51.262  13.567  -3.707  1.00 25.51  ? 272 THR D CB  1 
ATOM   8910  O  OG1 . THR D 1 272 ? 52.163  12.722  -4.403  1.00 24.63  ? 272 THR D OG1 1 
ATOM   8911  C  CG2 . THR D 1 272 ? 50.673  14.614  -4.634  1.00 27.13  ? 272 THR D CG2 1 
ATOM   8912  N  N   . MET D 1 273 ? 50.381  14.718  -0.979  1.00 18.71  ? 273 MET D N   1 
ATOM   8913  C  CA  . MET D 1 273 ? 49.542  15.599  -0.211  1.00 20.86  ? 273 MET D CA  1 
ATOM   8914  C  C   . MET D 1 273 ? 50.415  16.417  0.753   1.00 22.10  ? 273 MET D C   1 
ATOM   8915  O  O   . MET D 1 273 ? 50.244  17.659  0.940   1.00 20.16  ? 273 MET D O   1 
ATOM   8916  C  CB  . MET D 1 273 ? 48.507  14.754  0.547   1.00 21.76  ? 273 MET D CB  1 
ATOM   8917  C  CG  . MET D 1 273 ? 47.409  14.119  -0.302  1.00 21.21  ? 273 MET D CG  1 
ATOM   8918  S  SD  . MET D 1 273 ? 46.361  13.089  0.739   1.00 25.81  ? 273 MET D SD  1 
ATOM   8919  C  CE  . MET D 1 273 ? 45.208  12.499  -0.491  1.00 26.89  ? 273 MET D CE  1 
ATOM   8920  N  N   . LEU D 1 274 ? 51.376  15.730  1.373   1.00 18.85  ? 274 LEU D N   1 
ATOM   8921  C  CA  . LEU D 1 274 ? 52.255  16.434  2.297   1.00 21.35  ? 274 LEU D CA  1 
ATOM   8922  C  C   . LEU D 1 274 ? 53.121  17.489  1.592   1.00 20.60  ? 274 LEU D C   1 
ATOM   8923  O  O   . LEU D 1 274 ? 53.336  18.564  2.165   1.00 17.60  ? 274 LEU D O   1 
ATOM   8924  C  CB  . LEU D 1 274 ? 53.157  15.451  3.030   1.00 22.02  ? 274 LEU D CB  1 
ATOM   8925  C  CG  . LEU D 1 274 ? 52.535  14.645  4.189   1.00 23.02  ? 274 LEU D CG  1 
ATOM   8926  C  CD1 . LEU D 1 274 ? 53.430  13.522  4.683   1.00 22.56  ? 274 LEU D CD1 1 
ATOM   8927  C  CD2 . LEU D 1 274 ? 52.305  15.627  5.298   1.00 22.48  ? 274 LEU D CD2 1 
ATOM   8928  N  N   . GLU D 1 275 ? 53.625  17.187  0.388   1.00 21.44  ? 275 GLU D N   1 
ATOM   8929  C  CA  . GLU D 1 275 ? 54.367  18.178  -0.379  1.00 24.28  ? 275 GLU D CA  1 
ATOM   8930  C  C   . GLU D 1 275 ? 53.545  19.428  -0.684  1.00 21.84  ? 275 GLU D C   1 
ATOM   8931  O  O   . GLU D 1 275 ? 54.026  20.558  -0.505  1.00 21.47  ? 275 GLU D O   1 
ATOM   8932  C  CB  . GLU D 1 275 ? 54.841  17.663  -1.736  1.00 34.00  ? 275 GLU D CB  1 
ATOM   8933  C  CG  . GLU D 1 275 ? 56.131  16.860  -1.614  1.00 43.81  ? 275 GLU D CG  1 
ATOM   8934  C  CD  . GLU D 1 275 ? 56.428  15.989  -2.804  1.00 45.04  ? 275 GLU D CD  1 
ATOM   8935  O  OE1 . GLU D 1 275 ? 55.809  16.180  -3.838  1.00 43.49  ? 275 GLU D OE1 1 
ATOM   8936  O  OE2 . GLU D 1 275 ? 57.213  15.074  -2.600  1.00 45.35  ? 275 GLU D OE2 1 
ATOM   8937  N  N   . ARG D 1 276 ? 52.305  19.212  -1.097  1.00 19.75  ? 276 ARG D N   1 
ATOM   8938  C  CA  . ARG D 1 276 ? 51.419  20.323  -1.393  1.00 21.89  ? 276 ARG D CA  1 
ATOM   8939  C  C   . ARG D 1 276 ? 51.191  21.157  -0.156  1.00 22.99  ? 276 ARG D C   1 
ATOM   8940  O  O   . ARG D 1 276 ? 51.098  22.376  -0.274  1.00 23.35  ? 276 ARG D O   1 
ATOM   8941  C  CB  . ARG D 1 276 ? 50.077  19.881  -1.988  1.00 24.05  ? 276 ARG D CB  1 
ATOM   8942  C  CG  . ARG D 1 276 ? 50.324  19.378  -3.406  1.00 31.02  ? 276 ARG D CG  1 
ATOM   8943  C  CD  . ARG D 1 276 ? 49.474  18.313  -3.974  1.00 34.74  ? 276 ARG D CD  1 
ATOM   8944  N  NE  . ARG D 1 276 ? 48.117  18.824  -3.914  1.00 37.08  ? 276 ARG D NE  1 
ATOM   8945  C  CZ  . ARG D 1 276 ? 47.513  19.421  -4.889  1.00 44.12  ? 276 ARG D CZ  1 
ATOM   8946  N  NH1 . ARG D 1 276 ? 48.167  19.435  -6.017  1.00 55.07  ? 276 ARG D NH1 1 
ATOM   8947  N  NH2 . ARG D 1 276 ? 46.308  19.992  -4.736  1.00 36.61  ? 276 ARG D NH2 1 
ATOM   8948  N  N   . MET D 1 277 ? 51.024  20.482  1.008   1.00 21.85  ? 277 MET D N   1 
ATOM   8949  C  CA  . MET D 1 277 ? 50.679  21.201  2.217   1.00 22.58  ? 277 MET D CA  1 
ATOM   8950  C  C   . MET D 1 277 ? 51.893  22.034  2.657   1.00 21.82  ? 277 MET D C   1 
ATOM   8951  O  O   . MET D 1 277 ? 51.744  23.202  3.035   1.00 20.21  ? 277 MET D O   1 
ATOM   8952  C  CB  . MET D 1 277 ? 50.294  20.242  3.348   1.00 22.68  ? 277 MET D CB  1 
ATOM   8953  C  CG  . MET D 1 277 ? 48.973  19.561  3.202   1.00 23.27  ? 277 MET D CG  1 
ATOM   8954  S  SD  . MET D 1 277 ? 48.681  18.285  4.442   1.00 21.15  ? 277 MET D SD  1 
ATOM   8955  C  CE  . MET D 1 277 ? 48.588  19.393  5.841   1.00 20.33  ? 277 MET D CE  1 
ATOM   8956  N  N   . PHE D 1 278 ? 53.067  21.409  2.680   1.00 19.71  ? 278 PHE D N   1 
ATOM   8957  C  CA  . PHE D 1 278 ? 54.192  22.059  3.326   1.00 20.55  ? 278 PHE D CA  1 
ATOM   8958  C  C   . PHE D 1 278 ? 55.035  22.891  2.362   1.00 22.18  ? 278 PHE D C   1 
ATOM   8959  O  O   . PHE D 1 278 ? 55.594  23.951  2.761   1.00 24.08  ? 278 PHE D O   1 
ATOM   8960  C  CB  . PHE D 1 278 ? 55.079  20.974  3.918   1.00 22.91  ? 278 PHE D CB  1 
ATOM   8961  C  CG  . PHE D 1 278 ? 54.597  20.522  5.268   1.00 23.58  ? 278 PHE D CG  1 
ATOM   8962  C  CD1 . PHE D 1 278 ? 53.670  19.501  5.381   1.00 25.12  ? 278 PHE D CD1 1 
ATOM   8963  C  CD2 . PHE D 1 278 ? 55.045  21.161  6.420   1.00 24.08  ? 278 PHE D CD2 1 
ATOM   8964  C  CE1 . PHE D 1 278 ? 53.191  19.121  6.638   1.00 24.93  ? 278 PHE D CE1 1 
ATOM   8965  C  CE2 . PHE D 1 278 ? 54.588  20.758  7.676   1.00 25.15  ? 278 PHE D CE2 1 
ATOM   8966  C  CZ  . PHE D 1 278 ? 53.636  19.742  7.780   1.00 24.11  ? 278 PHE D CZ  1 
ATOM   8967  N  N   . LEU D 1 279 ? 55.159  22.426  1.104   1.00 19.60  ? 279 LEU D N   1 
ATOM   8968  C  CA  . LEU D 1 279 ? 56.000  23.184  0.186   1.00 22.16  ? 279 LEU D CA  1 
ATOM   8969  C  C   . LEU D 1 279 ? 55.175  24.171  -0.650  1.00 25.99  ? 279 LEU D C   1 
ATOM   8970  O  O   . LEU D 1 279 ? 55.711  25.154  -1.108  1.00 28.63  ? 279 LEU D O   1 
ATOM   8971  C  CB  . LEU D 1 279 ? 56.760  22.231  -0.715  1.00 23.49  ? 279 LEU D CB  1 
ATOM   8972  C  CG  . LEU D 1 279 ? 57.628  21.181  -0.045  1.00 22.53  ? 279 LEU D CG  1 
ATOM   8973  C  CD1 . LEU D 1 279 ? 58.250  20.394  -1.134  1.00 23.00  ? 279 LEU D CD1 1 
ATOM   8974  C  CD2 . LEU D 1 279 ? 58.632  21.821  0.841   1.00 24.97  ? 279 LEU D CD2 1 
ATOM   8975  N  N   . GLY D 1 280 ? 53.881  23.910  -0.861  1.00 27.58  ? 280 GLY D N   1 
ATOM   8976  C  CA  . GLY D 1 280 ? 53.005  24.807  -1.586  1.00 23.88  ? 280 GLY D CA  1 
ATOM   8977  C  C   . GLY D 1 280 ? 53.009  24.412  -3.049  1.00 22.92  ? 280 GLY D C   1 
ATOM   8978  O  O   . GLY D 1 280 ? 53.775  23.544  -3.419  1.00 23.32  ? 280 GLY D O   1 
ATOM   8979  N  N   . THR D 1 281 ? 52.208  25.125  -3.827  1.00 22.82  ? 281 THR D N   1 
ATOM   8980  C  CA  . THR D 1 281 ? 52.070  25.001  -5.262  1.00 21.43  ? 281 THR D CA  1 
ATOM   8981  C  C   . THR D 1 281 ? 52.210  26.376  -5.938  1.00 21.93  ? 281 THR D C   1 
ATOM   8982  O  O   . THR D 1 281 ? 52.444  27.389  -5.294  1.00 22.45  ? 281 THR D O   1 
ATOM   8983  C  CB  . THR D 1 281 ? 50.707  24.354  -5.507  1.00 18.30  ? 281 THR D CB  1 
ATOM   8984  O  OG1 . THR D 1 281 ? 49.673  25.275  -5.206  1.00 17.26  ? 281 THR D OG1 1 
ATOM   8985  C  CG2 . THR D 1 281 ? 50.621  23.088  -4.681  1.00 19.65  ? 281 THR D CG2 1 
ATOM   8986  N  N   . ALA D 1 282 ? 52.025  26.423  -7.253  1.00 21.69  ? 282 ALA D N   1 
ATOM   8987  C  CA  . ALA D 1 282 ? 52.018  27.698  -7.943  1.00 24.80  ? 282 ALA D CA  1 
ATOM   8988  C  C   . ALA D 1 282 ? 50.939  28.610  -7.368  1.00 24.92  ? 282 ALA D C   1 
ATOM   8989  O  O   . ALA D 1 282 ? 51.203  29.793  -7.197  1.00 23.51  ? 282 ALA D O   1 
ATOM   8990  C  CB  . ALA D 1 282 ? 51.826  27.515  -9.414  1.00 23.96  ? 282 ALA D CB  1 
ATOM   8991  N  N   . SER D 1 283 ? 49.779  28.051  -7.017  1.00 22.65  ? 283 SER D N   1 
ATOM   8992  C  CA  . SER D 1 283 ? 48.690  28.890  -6.573  1.00 25.85  ? 283 SER D CA  1 
ATOM   8993  C  C   . SER D 1 283 ? 48.480  28.910  -5.074  1.00 24.24  ? 283 SER D C   1 
ATOM   8994  O  O   . SER D 1 283 ? 47.610  29.635  -4.650  1.00 26.72  ? 283 SER D O   1 
ATOM   8995  C  CB  . SER D 1 283 ? 47.365  28.565  -7.261  1.00 33.93  ? 283 SER D CB  1 
ATOM   8996  O  OG  . SER D 1 283 ? 47.257  27.182  -7.502  1.00 32.83  ? 283 SER D OG  1 
ATOM   8997  N  N   . ALA D 1 284 ? 49.264  28.201  -4.263  1.00 22.47  ? 284 ALA D N   1 
ATOM   8998  C  CA  . ALA D 1 284 ? 49.037  28.252  -2.828  1.00 19.57  ? 284 ALA D CA  1 
ATOM   8999  C  C   . ALA D 1 284 ? 50.347  28.238  -2.102  1.00 18.06  ? 284 ALA D C   1 
ATOM   9000  O  O   . ALA D 1 284 ? 51.104  27.315  -2.250  1.00 22.20  ? 284 ALA D O   1 
ATOM   9001  C  CB  . ALA D 1 284 ? 48.264  27.046  -2.392  1.00 22.06  ? 284 ALA D CB  1 
ATOM   9002  N  N   . PRO D 1 285 ? 50.663  29.219  -1.269  1.00 18.19  ? 285 PRO D N   1 
ATOM   9003  C  CA  . PRO D 1 285 ? 51.952  29.227  -0.580  1.00 20.24  ? 285 PRO D CA  1 
ATOM   9004  C  C   . PRO D 1 285 ? 52.225  27.997  0.271   1.00 20.63  ? 285 PRO D C   1 
ATOM   9005  O  O   . PRO D 1 285 ? 53.351  27.554  0.348   1.00 19.43  ? 285 PRO D O   1 
ATOM   9006  C  CB  . PRO D 1 285 ? 51.802  30.516  0.340   1.00 25.74  ? 285 PRO D CB  1 
ATOM   9007  C  CG  . PRO D 1 285 ? 50.920  31.410  -0.519  1.00 23.41  ? 285 PRO D CG  1 
ATOM   9008  C  CD  . PRO D 1 285 ? 49.864  30.415  -1.014  1.00 20.05  ? 285 PRO D CD  1 
ATOM   9009  N  N   . HIS D 1 286 ? 51.169  27.530  0.972   1.00 21.22  ? 286 HIS D N   1 
ATOM   9010  C  CA  . HIS D 1 286 ? 51.171  26.373  1.852   1.00 20.10  ? 286 HIS D CA  1 
ATOM   9011  C  C   . HIS D 1 286 ? 49.747  26.245  2.382   1.00 19.79  ? 286 HIS D C   1 
ATOM   9012  O  O   . HIS D 1 286 ? 48.946  27.141  2.215   1.00 20.27  ? 286 HIS D O   1 
ATOM   9013  C  CB  . HIS D 1 286 ? 52.168  26.501  3.027   1.00 19.72  ? 286 HIS D CB  1 
ATOM   9014  C  CG  . HIS D 1 286 ? 51.961  27.698  3.894   1.00 21.60  ? 286 HIS D CG  1 
ATOM   9015  N  ND1 . HIS D 1 286 ? 52.705  28.855  3.782   1.00 21.08  ? 286 HIS D ND1 1 
ATOM   9016  C  CD2 . HIS D 1 286 ? 51.057  27.931  4.876   1.00 22.44  ? 286 HIS D CD2 1 
ATOM   9017  C  CE1 . HIS D 1 286 ? 52.270  29.718  4.701   1.00 20.91  ? 286 HIS D CE1 1 
ATOM   9018  N  NE2 . HIS D 1 286 ? 51.247  29.198  5.352   1.00 24.11  ? 286 HIS D NE2 1 
ATOM   9019  N  N   . ASP D 1 287 ? 49.438  25.112  3.009   1.00 20.51  ? 287 ASP D N   1 
ATOM   9020  C  CA  . ASP D 1 287 ? 48.141  24.835  3.603   1.00 18.00  ? 287 ASP D CA  1 
ATOM   9021  C  C   . ASP D 1 287 ? 47.987  25.730  4.832   1.00 17.52  ? 287 ASP D C   1 
ATOM   9022  O  O   . ASP D 1 287 ? 48.799  25.683  5.764   1.00 17.67  ? 287 ASP D O   1 
ATOM   9023  C  CB  . ASP D 1 287 ? 48.115  23.346  3.941   1.00 20.35  ? 287 ASP D CB  1 
ATOM   9024  C  CG  . ASP D 1 287 ? 46.803  22.795  4.485   1.00 22.25  ? 287 ASP D CG  1 
ATOM   9025  O  OD1 . ASP D 1 287 ? 45.981  23.632  4.969   1.00 23.35  ? 287 ASP D OD1 1 
ATOM   9026  O  OD2 . ASP D 1 287 ? 46.594  21.539  4.370   1.00 22.79  ? 287 ASP D OD2 1 
ATOM   9027  N  N   . ARG D 1 288 ? 46.957  26.561  4.826   1.00 16.04  ? 288 ARG D N   1 
ATOM   9028  C  CA  . ARG D 1 288 ? 46.687  27.454  5.935   1.00 16.75  ? 288 ARG D CA  1 
ATOM   9029  C  C   . ARG D 1 288 ? 46.439  26.723  7.249   1.00 17.39  ? 288 ARG D C   1 
ATOM   9030  O  O   . ARG D 1 288 ? 46.665  27.310  8.303   1.00 20.69  ? 288 ARG D O   1 
ATOM   9031  C  CB  . ARG D 1 288 ? 45.470  28.296  5.575   1.00 21.15  ? 288 ARG D CB  1 
ATOM   9032  C  CG  . ARG D 1 288 ? 45.790  29.373  4.557   1.00 25.80  ? 288 ARG D CG  1 
ATOM   9033  C  CD  . ARG D 1 288 ? 46.461  30.534  5.293   1.00 29.76  ? 288 ARG D CD  1 
ATOM   9034  N  NE  . ARG D 1 288 ? 45.436  31.315  6.008   1.00 40.52  ? 288 ARG D NE  1 
ATOM   9035  C  CZ  . ARG D 1 288 ? 45.512  31.853  7.257   1.00 43.89  ? 288 ARG D CZ  1 
ATOM   9036  N  NH1 . ARG D 1 288 ? 46.637  31.833  7.969   1.00 41.53  ? 288 ARG D NH1 1 
ATOM   9037  N  NH2 . ARG D 1 288 ? 44.409  32.274  7.839   1.00 37.76  ? 288 ARG D NH2 1 
ATOM   9038  N  N   . ILE D 1 289 ? 46.110  25.427  7.252   1.00 19.27  ? 289 ILE D N   1 
ATOM   9039  C  CA  . ILE D 1 289 ? 45.985  24.769  8.541   1.00 20.01  ? 289 ILE D CA  1 
ATOM   9040  C  C   . ILE D 1 289 ? 47.317  24.743  9.306   1.00 21.70  ? 289 ILE D C   1 
ATOM   9041  O  O   . ILE D 1 289 ? 47.311  24.662  10.551  1.00 23.08  ? 289 ILE D O   1 
ATOM   9042  C  CB  . ILE D 1 289 ? 45.397  23.374  8.348   1.00 22.49  ? 289 ILE D CB  1 
ATOM   9043  C  CG1 . ILE D 1 289 ? 44.586  22.941  9.576   1.00 22.00  ? 289 ILE D CG1 1 
ATOM   9044  C  CG2 . ILE D 1 289 ? 46.505  22.376  8.024   1.00 25.19  ? 289 ILE D CG2 1 
ATOM   9045  C  CD1 . ILE D 1 289 ? 43.965  21.531  9.460   1.00 24.44  ? 289 ILE D CD1 1 
ATOM   9046  N  N   . LEU D 1 290 ? 48.452  24.777  8.590   1.00 19.43  ? 290 LEU D N   1 
ATOM   9047  C  CA  . LEU D 1 290 ? 49.778  24.719  9.212   1.00 19.48  ? 290 LEU D CA  1 
ATOM   9048  C  C   . LEU D 1 290 ? 50.125  26.040  9.915   1.00 17.24  ? 290 LEU D C   1 
ATOM   9049  O  O   . LEU D 1 290 ? 51.062  26.103  10.720  1.00 17.79  ? 290 LEU D O   1 
ATOM   9050  C  CB  . LEU D 1 290 ? 50.851  24.356  8.178   1.00 20.39  ? 290 LEU D CB  1 
ATOM   9051  C  CG  . LEU D 1 290 ? 50.678  23.013  7.497   1.00 21.31  ? 290 LEU D CG  1 
ATOM   9052  C  CD1 . LEU D 1 290 ? 51.694  22.776  6.465   1.00 20.37  ? 290 LEU D CD1 1 
ATOM   9053  C  CD2 . LEU D 1 290 ? 50.734  21.901  8.494   1.00 26.68  ? 290 LEU D CD2 1 
ATOM   9054  N  N   . ASP D 1 291 ? 49.347  27.093  9.662   1.00 15.93  ? 291 ASP D N   1 
ATOM   9055  C  CA  . ASP D 1 291 ? 49.580  28.298  10.412  1.00 18.01  ? 291 ASP D CA  1 
ATOM   9056  C  C   . ASP D 1 291 ? 49.051  28.157  11.831  1.00 18.98  ? 291 ASP D C   1 
ATOM   9057  O  O   . ASP D 1 291 ? 49.211  29.055  12.629  1.00 19.25  ? 291 ASP D O   1 
ATOM   9058  C  CB  . ASP D 1 291 ? 49.024  29.535  9.717   1.00 23.29  ? 291 ASP D CB  1 
ATOM   9059  C  CG  . ASP D 1 291 ? 49.775  29.983  8.476   1.00 25.16  ? 291 ASP D CG  1 
ATOM   9060  O  OD1 . ASP D 1 291 ? 50.975  29.654  8.367   1.00 24.64  ? 291 ASP D OD1 1 
ATOM   9061  O  OD2 . ASP D 1 291 ? 49.082  30.429  7.547   1.00 32.33  ? 291 ASP D OD2 1 
ATOM   9062  N  N   . PHE D 1 292 ? 48.342  27.085  12.137  1.00 19.15  ? 292 PHE D N   1 
ATOM   9063  C  CA  . PHE D 1 292 ? 47.806  26.874  13.468  1.00 18.39  ? 292 PHE D CA  1 
ATOM   9064  C  C   . PHE D 1 292 ? 48.195  25.491  13.993  1.00 19.36  ? 292 PHE D C   1 
ATOM   9065  O  O   . PHE D 1 292 ? 47.667  25.065  15.027  1.00 21.23  ? 292 PHE D O   1 
ATOM   9066  C  CB  . PHE D 1 292 ? 46.281  26.967  13.429  1.00 20.11  ? 292 PHE D CB  1 
ATOM   9067  C  CG  . PHE D 1 292 ? 45.868  28.284  12.872  1.00 19.37  ? 292 PHE D CG  1 
ATOM   9068  C  CD1 . PHE D 1 292 ? 45.802  29.379  13.719  1.00 21.41  ? 292 PHE D CD1 1 
ATOM   9069  C  CD2 . PHE D 1 292 ? 45.596  28.406  11.524  1.00 19.67  ? 292 PHE D CD2 1 
ATOM   9070  C  CE1 . PHE D 1 292 ? 45.424  30.611  13.216  1.00 23.32  ? 292 PHE D CE1 1 
ATOM   9071  C  CE2 . PHE D 1 292 ? 45.252  29.657  11.018  1.00 23.20  ? 292 PHE D CE2 1 
ATOM   9072  C  CZ  . PHE D 1 292 ? 45.223  30.778  11.882  1.00 21.52  ? 292 PHE D CZ  1 
ATOM   9073  N  N   . SER D 1 293 ? 49.069  24.780  13.288  1.00 17.95  ? 293 SER D N   1 
ATOM   9074  C  CA  . SER D 1 293 ? 49.380  23.415  13.636  1.00 19.33  ? 293 SER D CA  1 
ATOM   9075  C  C   . SER D 1 293 ? 50.878  23.199  13.376  1.00 21.47  ? 293 SER D C   1 
ATOM   9076  O  O   . SER D 1 293 ? 51.333  23.481  12.253  1.00 22.41  ? 293 SER D O   1 
ATOM   9077  C  CB  . SER D 1 293 ? 48.526  22.469  12.801  1.00 16.87  ? 293 SER D CB  1 
ATOM   9078  O  OG  . SER D 1 293 ? 47.193  22.906  12.644  1.00 16.66  ? 293 SER D OG  1 
ATOM   9079  N  N   . THR D 1 294 ? 51.618  22.708  14.379  1.00 19.57  ? 294 THR D N   1 
ATOM   9080  C  CA  . THR D 1 294 ? 53.038  22.372  14.254  1.00 21.83  ? 294 THR D CA  1 
ATOM   9081  C  C   . THR D 1 294 ? 53.254  20.878  14.395  1.00 20.53  ? 294 THR D C   1 
ATOM   9082  O  O   . THR D 1 294 ? 52.833  20.305  15.413  1.00 19.82  ? 294 THR D O   1 
ATOM   9083  C  CB  . THR D 1 294 ? 53.803  23.032  15.381  1.00 24.98  ? 294 THR D CB  1 
ATOM   9084  O  OG1 . THR D 1 294 ? 53.537  24.401  15.253  1.00 22.91  ? 294 THR D OG1 1 
ATOM   9085  C  CG2 . THR D 1 294 ? 55.283  22.850  15.203  1.00 24.53  ? 294 THR D CG2 1 
ATOM   9086  N  N   . ALA D 1 295 ? 53.875  20.268  13.383  1.00 20.99  ? 295 ALA D N   1 
ATOM   9087  C  CA  . ALA D 1 295 ? 54.197  18.852  13.437  1.00 22.03  ? 295 ALA D CA  1 
ATOM   9088  C  C   . ALA D 1 295 ? 55.463  18.632  14.264  1.00 22.26  ? 295 ALA D C   1 
ATOM   9089  O  O   . ALA D 1 295 ? 56.441  19.318  14.072  1.00 22.07  ? 295 ALA D O   1 
ATOM   9090  C  CB  . ALA D 1 295 ? 54.378  18.356  12.056  1.00 22.12  ? 295 ALA D CB  1 
ATOM   9091  N  N   . VAL D 1 296 ? 55.428  17.718  15.210  1.00 23.77  ? 296 VAL D N   1 
ATOM   9092  C  CA  . VAL D 1 296 ? 56.566  17.466  16.091  1.00 21.28  ? 296 VAL D CA  1 
ATOM   9093  C  C   . VAL D 1 296 ? 57.069  16.016  15.967  1.00 21.40  ? 296 VAL D C   1 
ATOM   9094  O  O   . VAL D 1 296 ? 58.134  15.692  16.517  1.00 25.18  ? 296 VAL D O   1 
ATOM   9095  C  CB  . VAL D 1 296 ? 56.314  17.875  17.555  1.00 20.10  ? 296 VAL D CB  1 
ATOM   9096  C  CG1 . VAL D 1 296 ? 55.754  19.250  17.615  1.00 21.06  ? 296 VAL D CG1 1 
ATOM   9097  C  CG2 . VAL D 1 296 ? 55.319  16.983  18.226  1.00 23.58  ? 296 VAL D CG2 1 
ATOM   9098  N  N   . THR D 1 297 ? 56.348  15.142  15.231  1.00 19.99  ? 297 THR D N   1 
ATOM   9099  C  CA  . THR D 1 297 ? 56.874  13.830  14.867  1.00 19.41  ? 297 THR D CA  1 
ATOM   9100  C  C   . THR D 1 297 ? 56.515  13.580  13.428  1.00 17.30  ? 297 THR D C   1 
ATOM   9101  O  O   . THR D 1 297 ? 55.707  14.281  12.882  1.00 22.04  ? 297 THR D O   1 
ATOM   9102  C  CB  . THR D 1 297 ? 56.334  12.661  15.694  1.00 21.34  ? 297 THR D CB  1 
ATOM   9103  O  OG1 . THR D 1 297 ? 54.959  12.412  15.432  1.00 21.64  ? 297 THR D OG1 1 
ATOM   9104  C  CG2 . THR D 1 297 ? 56.573  12.893  17.155  1.00 21.45  ? 297 THR D CG2 1 
ATOM   9105  N  N   . GLY D 1 298 ? 57.194  12.614  12.838  1.00 17.07  ? 298 GLY D N   1 
ATOM   9106  C  CA  . GLY D 1 298 ? 56.925  12.180  11.495  1.00 18.21  ? 298 GLY D CA  1 
ATOM   9107  C  C   . GLY D 1 298 ? 57.558  10.823  11.292  1.00 19.68  ? 298 GLY D C   1 
ATOM   9108  O  O   . GLY D 1 298 ? 58.749  10.726  11.409  1.00 23.00  ? 298 GLY D O   1 
ATOM   9109  N  N   . SER D 1 299 ? 56.778  9.784   10.991  1.00 21.73  ? 299 SER D N   1 
ATOM   9110  C  CA  . SER D 1 299 ? 57.321  8.493   10.660  1.00 19.18  ? 299 SER D CA  1 
ATOM   9111  C  C   . SER D 1 299 ? 56.448  7.791   9.647   1.00 22.42  ? 299 SER D C   1 
ATOM   9112  O  O   . SER D 1 299 ? 55.244  8.063   9.567   1.00 23.22  ? 299 SER D O   1 
ATOM   9113  C  CB  . SER D 1 299 ? 57.422  7.625   11.899  1.00 22.30  ? 299 SER D CB  1 
ATOM   9114  O  OG  . SER D 1 299 ? 58.132  8.308   12.915  1.00 19.28  ? 299 SER D OG  1 
ATOM   9115  N  N   . LEU D 1 300 ? 57.061  6.798   8.974   1.00 20.00  ? 300 LEU D N   1 
ATOM   9116  C  CA  . LEU D 1 300 ? 56.397  6.007   7.963   1.00 18.82  ? 300 LEU D CA  1 
ATOM   9117  C  C   . LEU D 1 300 ? 56.603  4.550   8.310   1.00 20.02  ? 300 LEU D C   1 
ATOM   9118  O  O   . LEU D 1 300 ? 57.700  4.167   8.686   1.00 23.24  ? 300 LEU D O   1 
ATOM   9119  C  CB  . LEU D 1 300 ? 56.967  6.361   6.603   1.00 20.22  ? 300 LEU D CB  1 
ATOM   9120  C  CG  . LEU D 1 300 ? 56.243  5.790   5.369   1.00 26.61  ? 300 LEU D CG  1 
ATOM   9121  C  CD1 . LEU D 1 300 ? 56.617  6.470   4.063   1.00 33.91  ? 300 LEU D CD1 1 
ATOM   9122  C  CD2 . LEU D 1 300 ? 56.589  4.363   5.149   1.00 31.05  ? 300 LEU D CD2 1 
ATOM   9123  N  N   . PHE D 1 301 ? 55.556  3.743   8.148   1.00 19.36  ? 301 PHE D N   1 
ATOM   9124  C  CA  . PHE D 1 301 ? 55.538  2.340   8.529   1.00 17.86  ? 301 PHE D CA  1 
ATOM   9125  C  C   . PHE D 1 301 ? 54.800  1.565   7.458   1.00 20.12  ? 301 PHE D C   1 
ATOM   9126  O  O   . PHE D 1 301 ? 53.891  2.095   6.753   1.00 22.96  ? 301 PHE D O   1 
ATOM   9127  C  CB  . PHE D 1 301 ? 54.813  2.062   9.850   1.00 15.25  ? 301 PHE D CB  1 
ATOM   9128  C  CG  . PHE D 1 301 ? 55.405  2.883   10.966  1.00 15.97  ? 301 PHE D CG  1 
ATOM   9129  C  CD1 . PHE D 1 301 ? 54.945  4.161   11.231  1.00 15.74  ? 301 PHE D CD1 1 
ATOM   9130  C  CD2 . PHE D 1 301 ? 56.454  2.407   11.760  1.00 17.76  ? 301 PHE D CD2 1 
ATOM   9131  C  CE1 . PHE D 1 301 ? 55.429  4.895   12.298  1.00 17.16  ? 301 PHE D CE1 1 
ATOM   9132  C  CE2 . PHE D 1 301 ? 56.928  3.154   12.852  1.00 15.70  ? 301 PHE D CE2 1 
ATOM   9133  C  CZ  . PHE D 1 301 ? 56.409  4.392   13.119  1.00 15.80  ? 301 PHE D CZ  1 
ATOM   9134  N  N   . PHE D 1 302 ? 55.209  0.297   7.306   1.00 21.28  ? 302 PHE D N   1 
ATOM   9135  C  CA  . PHE D 1 302 ? 54.445  -0.672  6.538   1.00 21.09  ? 302 PHE D CA  1 
ATOM   9136  C  C   . PHE D 1 302 ? 53.714  -1.585  7.496   1.00 23.83  ? 302 PHE D C   1 
ATOM   9137  O  O   . PHE D 1 302 ? 54.302  -2.118  8.446   1.00 27.55  ? 302 PHE D O   1 
ATOM   9138  C  CB  . PHE D 1 302 ? 55.401  -1.460  5.650   1.00 21.57  ? 302 PHE D CB  1 
ATOM   9139  C  CG  . PHE D 1 302 ? 54.667  -2.468  4.792   1.00 21.59  ? 302 PHE D CG  1 
ATOM   9140  C  CD1 . PHE D 1 302 ? 53.898  -2.051  3.731   1.00 22.20  ? 302 PHE D CD1 1 
ATOM   9141  C  CD2 . PHE D 1 302 ? 54.734  -3.813  5.091   1.00 23.01  ? 302 PHE D CD2 1 
ATOM   9142  C  CE1 . PHE D 1 302 ? 53.175  -2.973  2.998   1.00 25.73  ? 302 PHE D CE1 1 
ATOM   9143  C  CE2 . PHE D 1 302 ? 54.060  -4.752  4.320   1.00 22.89  ? 302 PHE D CE2 1 
ATOM   9144  C  CZ  . PHE D 1 302 ? 53.276  -4.349  3.292   1.00 23.95  ? 302 PHE D CZ  1 
ATOM   9145  N  N   . THR D 1 303 ? 52.422  -1.731  7.272   1.00 24.45  ? 303 THR D N   1 
ATOM   9146  C  CA  . THR D 1 303 ? 51.599  -2.605  8.099   1.00 23.48  ? 303 THR D CA  1 
ATOM   9147  C  C   . THR D 1 303 ? 51.308  -3.848  7.253   1.00 23.68  ? 303 THR D C   1 
ATOM   9148  O  O   . THR D 1 303 ? 50.464  -3.830  6.361   1.00 23.18  ? 303 THR D O   1 
ATOM   9149  C  CB  . THR D 1 303 ? 50.286  -1.949  8.555   1.00 24.99  ? 303 THR D CB  1 
ATOM   9150  O  OG1 . THR D 1 303 ? 49.568  -1.386  7.464   1.00 23.67  ? 303 THR D OG1 1 
ATOM   9151  C  CG2 . THR D 1 303 ? 50.491  -0.698  9.350   1.00 28.30  ? 303 THR D CG2 1 
ATOM   9152  N  N   . PRO D 1 304 ? 51.999  -4.974  7.504   1.00 25.90  ? 304 PRO D N   1 
ATOM   9153  C  CA  . PRO D 1 304 ? 51.791  -6.179  6.727   1.00 26.86  ? 304 PRO D CA  1 
ATOM   9154  C  C   . PRO D 1 304 ? 50.412  -6.785  6.899   1.00 28.07  ? 304 PRO D C   1 
ATOM   9155  O  O   . PRO D 1 304 ? 49.702  -6.503  7.874   1.00 31.74  ? 304 PRO D O   1 
ATOM   9156  C  CB  . PRO D 1 304 ? 52.844  -7.143  7.248   1.00 26.34  ? 304 PRO D CB  1 
ATOM   9157  C  CG  . PRO D 1 304 ? 53.606  -6.464  8.336   1.00 26.43  ? 304 PRO D CG  1 
ATOM   9158  C  CD  . PRO D 1 304 ? 52.996  -5.132  8.570   1.00 27.66  ? 304 PRO D CD  1 
ATOM   9159  N  N   . ALA D 1 305 ? 50.092  -7.675  5.949   1.00 29.74  ? 305 ALA D N   1 
ATOM   9160  C  CA  . ALA D 1 305 ? 48.963  -8.573  6.123   1.00 33.69  ? 305 ALA D CA  1 
ATOM   9161  C  C   . ALA D 1 305 ? 49.150  -9.386  7.406   1.00 34.37  ? 305 ALA D C   1 
ATOM   9162  O  O   . ALA D 1 305 ? 50.262  -9.668  7.818   1.00 40.19  ? 305 ALA D O   1 
ATOM   9163  C  CB  . ALA D 1 305 ? 48.782  -9.447  4.917   1.00 36.91  ? 305 ALA D CB  1 
ATOM   9164  N  N   . ALA D 1 306 ? 48.041  -9.732  8.051   1.00 37.21  ? 306 ALA D N   1 
ATOM   9165  C  CA  . ALA D 1 306 ? 48.045  -10.490 9.286   1.00 37.50  ? 306 ALA D CA  1 
ATOM   9166  C  C   . ALA D 1 306 ? 48.741  -11.822 9.077   1.00 39.07  ? 306 ALA D C   1 
ATOM   9167  O  O   . ALA D 1 306 ? 49.425  -12.229 10.015  1.00 42.59  ? 306 ALA D O   1 
ATOM   9168  C  CB  . ALA D 1 306 ? 46.632  -10.736 9.747   1.00 38.21  ? 306 ALA D CB  1 
ATOM   9169  N  N   . ASP D 1 307 ? 48.560  -12.471 7.893   1.00 41.46  ? 307 ASP D N   1 
ATOM   9170  C  CA  . ASP D 1 307 ? 49.211  -13.751 7.584   1.00 46.66  ? 307 ASP D CA  1 
ATOM   9171  C  C   . ASP D 1 307 ? 50.725  -13.658 7.695   1.00 44.68  ? 307 ASP D C   1 
ATOM   9172  O  O   . ASP D 1 307 ? 51.365  -14.551 8.247   1.00 51.09  ? 307 ASP D O   1 
ATOM   9173  C  CB  . ASP D 1 307 ? 49.053  -14.228 6.154   1.00 50.28  ? 307 ASP D CB  1 
ATOM   9174  C  CG  . ASP D 1 307 ? 47.619  -14.126 5.689   1.00 64.03  ? 307 ASP D CG  1 
ATOM   9175  O  OD1 . ASP D 1 307 ? 46.773  -14.733 6.354   1.00 55.91  ? 307 ASP D OD1 1 
ATOM   9176  O  OD2 . ASP D 1 307 ? 47.371  -13.389 4.723   1.00 81.40  ? 307 ASP D OD2 1 
ATOM   9177  N  N   . PHE D 1 308 ? 51.280  -12.547 7.208   1.00 43.54  ? 308 PHE D N   1 
ATOM   9178  C  CA  . PHE D 1 308 ? 52.722  -12.354 7.271   1.00 35.86  ? 308 PHE D CA  1 
ATOM   9179  C  C   . PHE D 1 308 ? 53.211  -12.432 8.722   1.00 35.59  ? 308 PHE D C   1 
ATOM   9180  O  O   . PHE D 1 308 ? 54.260  -13.014 8.993   1.00 38.47  ? 308 PHE D O   1 
ATOM   9181  C  CB  . PHE D 1 308 ? 53.083  -11.067 6.546   1.00 32.22  ? 308 PHE D CB  1 
ATOM   9182  C  CG  . PHE D 1 308 ? 54.566  -10.774 6.581   1.00 39.68  ? 308 PHE D CG  1 
ATOM   9183  C  CD1 . PHE D 1 308 ? 55.406  -11.340 5.619   1.00 48.37  ? 308 PHE D CD1 1 
ATOM   9184  C  CD2 . PHE D 1 308 ? 55.111  -9.927  7.559   1.00 36.80  ? 308 PHE D CD2 1 
ATOM   9185  C  CE1 . PHE D 1 308 ? 56.756  -11.043 5.624   1.00 51.13  ? 308 PHE D CE1 1 
ATOM   9186  C  CE2 . PHE D 1 308 ? 56.458  -9.637  7.551   1.00 36.68  ? 308 PHE D CE2 1 
ATOM   9187  C  CZ  . PHE D 1 308 ? 57.273  -10.198 6.597   1.00 46.24  ? 308 PHE D CZ  1 
ATOM   9188  N  N   . LEU D 1 309 ? 52.489  -11.853 9.688   1.00 33.18  ? 309 LEU D N   1 
ATOM   9189  C  CA  . LEU D 1 309 ? 52.961  -11.863 11.063  1.00 30.98  ? 309 LEU D CA  1 
ATOM   9190  C  C   . LEU D 1 309 ? 52.776  -13.245 11.685  1.00 37.57  ? 309 LEU D C   1 
ATOM   9191  O  O   . LEU D 1 309 ? 53.532  -13.522 12.621  1.00 38.16  ? 309 LEU D O   1 
ATOM   9192  C  CB  . LEU D 1 309 ? 52.208  -10.817 11.887  1.00 35.04  ? 309 LEU D CB  1 
ATOM   9193  C  CG  . LEU D 1 309 ? 52.327  -9.353  11.457  1.00 35.78  ? 309 LEU D CG  1 
ATOM   9194  C  CD1 . LEU D 1 309 ? 51.347  -8.567  12.190  1.00 32.65  ? 309 LEU D CD1 1 
ATOM   9195  C  CD2 . LEU D 1 309 ? 53.689  -8.765  11.778  1.00 40.28  ? 309 LEU D CD2 1 
ATOM   9196  N  N   . GLU D 1 310 ? 51.732  -14.032 11.267  1.00 46.09  ? 310 GLU D N   1 
ATOM   9197  C  CA  . GLU D 1 310 ? 51.406  -15.320 11.898  1.00 53.15  ? 310 GLU D CA  1 
ATOM   9198  C  C   . GLU D 1 310 ? 52.646  -16.196 11.638  1.00 60.88  ? 310 GLU D C   1 
ATOM   9199  O  O   . GLU D 1 310 ? 53.184  -16.765 12.596  1.00 59.20  ? 310 GLU D O   1 
ATOM   9200  C  CB  . GLU D 1 310 ? 50.012  -15.930 11.608  1.00 39.67  ? 310 GLU D CB  1 
ATOM   9201  N  N   . ASP D 1 311 ? 53.206  -16.132 10.411  1.00 47.56  ? 311 ASP D N   1 
ATOM   9202  C  CA  . ASP D 1 311 ? 54.021  -17.182 9.809   1.00 65.46  ? 311 ASP D CA  1 
ATOM   9203  C  C   . ASP D 1 311 ? 55.406  -17.317 10.469  1.00 86.13  ? 311 ASP D C   1 
ATOM   9204  O  O   . ASP D 1 311 ? 56.126  -18.293 10.224  1.00 109.43 ? 311 ASP D O   1 
ATOM   9205  C  CB  . ASP D 1 311 ? 54.154  -17.031 8.289   1.00 59.34  ? 311 ASP D CB  1 
ATOM   9206  C  CG  . ASP D 1 311 ? 55.436  -16.373 7.730   1.00 79.29  ? 311 ASP D CG  1 
ATOM   9207  O  OD1 . ASP D 1 311 ? 56.190  -15.564 8.418   1.00 61.81  ? 311 ASP D OD1 1 
ATOM   9208  O  OD2 . ASP D 1 311 ? 55.735  -16.663 6.550   1.00 110.96 ? 311 ASP D OD2 1 
ATOM   9209  N  N   . LEU D 1 312 ? 55.771  -16.380 11.353  1.00 76.96  ? 312 LEU D N   1 
ATOM   9210  C  CA  . LEU D 1 312 ? 57.129  -16.318 11.873  1.00 86.82  ? 312 LEU D CA  1 
ATOM   9211  C  C   . LEU D 1 312 ? 57.071  -16.521 13.409  1.00 59.93  ? 312 LEU D C   1 
ATOM   9212  O  O   . LEU D 1 312 ? 57.703  -17.518 13.831  1.00 69.95  ? 312 LEU D O   1 
ATOM   9213  C  CB  . LEU D 1 312 ? 57.822  -15.026 11.368  1.00 89.07  ? 312 LEU D CB  1 
ATOM   9214  C  CG  . LEU D 1 312 ? 57.198  -13.637 11.659  1.00 67.53  ? 312 LEU D CG  1 
ATOM   9215  C  CD1 . LEU D 1 312 ? 58.033  -12.724 12.513  1.00 59.90  ? 312 LEU D CD1 1 
ATOM   9216  C  CD2 . LEU D 1 312 ? 56.868  -12.888 10.418  1.00 65.28  ? 312 LEU D CD2 1 
ATOM   9217  N  N   . GLU E 1 7   ? 14.040  6.846   58.294  1.00 89.72  ? 7   GLU E N   1 
ATOM   9218  C  CA  . GLU E 1 7   ? 13.803  5.482   57.750  1.00 89.77  ? 7   GLU E CA  1 
ATOM   9219  C  C   . GLU E 1 7   ? 14.719  4.447   58.456  1.00 81.80  ? 7   GLU E C   1 
ATOM   9220  O  O   . GLU E 1 7   ? 15.731  4.760   59.127  1.00 59.49  ? 7   GLU E O   1 
ATOM   9221  C  CB  . GLU E 1 7   ? 13.827  5.647   56.216  1.00 77.25  ? 7   GLU E CB  1 
ATOM   9222  N  N   . PRO E 1 8   ? 14.273  3.162   58.459  1.00 82.72  ? 8   PRO E N   1 
ATOM   9223  C  CA  . PRO E 1 8   ? 15.176  2.004   58.278  1.00 65.53  ? 8   PRO E CA  1 
ATOM   9224  C  C   . PRO E 1 8   ? 15.230  1.677   56.767  1.00 57.37  ? 8   PRO E C   1 
ATOM   9225  O  O   . PRO E 1 8   ? 14.272  2.049   56.077  1.00 44.73  ? 8   PRO E O   1 
ATOM   9226  C  CB  . PRO E 1 8   ? 14.449  0.916   59.174  1.00 63.65  ? 8   PRO E CB  1 
ATOM   9227  C  CG  . PRO E 1 8   ? 12.956  1.317   59.121  1.00 67.86  ? 8   PRO E CG  1 
ATOM   9228  C  CD  . PRO E 1 8   ? 12.855  2.788   58.719  1.00 68.81  ? 8   PRO E CD  1 
ATOM   9229  N  N   . GLU E 1 9   ? 16.309  1.035   56.231  1.00 55.47  ? 9   GLU E N   1 
ATOM   9230  C  CA  . GLU E 1 9   ? 16.414  0.687   54.796  1.00 55.63  ? 9   GLU E CA  1 
ATOM   9231  C  C   . GLU E 1 9   ? 15.558  -0.594  54.587  1.00 47.50  ? 9   GLU E C   1 
ATOM   9232  O  O   . GLU E 1 9   ? 15.749  -1.661  55.209  1.00 39.94  ? 9   GLU E O   1 
ATOM   9233  C  CB  . GLU E 1 9   ? 17.837  0.714   54.161  1.00 42.38  ? 9   GLU E CB  1 
ATOM   9234  N  N   . PRO E 1 10  ? 14.503  -0.552  53.741  1.00 37.18  ? 10  PRO E N   1 
ATOM   9235  C  CA  . PRO E 1 10  ? 13.881  -1.773  53.225  1.00 34.76  ? 10  PRO E CA  1 
ATOM   9236  C  C   . PRO E 1 10  ? 14.810  -2.533  52.286  1.00 34.11  ? 10  PRO E C   1 
ATOM   9237  O  O   . PRO E 1 10  ? 15.725  -1.959  51.710  1.00 34.52  ? 10  PRO E O   1 
ATOM   9238  C  CB  . PRO E 1 10  ? 12.647  -1.313  52.444  1.00 28.33  ? 10  PRO E CB  1 
ATOM   9239  C  CG  . PRO E 1 10  ? 13.026  0.051   52.025  1.00 32.23  ? 10  PRO E CG  1 
ATOM   9240  C  CD  . PRO E 1 10  ? 13.844  0.627   53.185  1.00 34.37  ? 10  PRO E CD  1 
ATOM   9241  N  N   . GLN E 1 11  ? 14.522  -3.825  52.107  1.00 36.00  ? 11  GLN E N   1 
ATOM   9242  C  CA  . GLN E 1 11  ? 15.089  -4.605  51.028  1.00 29.44  ? 11  GLN E CA  1 
ATOM   9243  C  C   . GLN E 1 11  ? 14.556  -4.024  49.729  1.00 31.74  ? 11  GLN E C   1 
ATOM   9244  O  O   . GLN E 1 11  ? 13.637  -3.182  49.755  1.00 31.68  ? 11  GLN E O   1 
ATOM   9245  C  CB  . GLN E 1 11  ? 14.757  -6.100  51.188  1.00 30.15  ? 11  GLN E CB  1 
ATOM   9246  C  CG  . GLN E 1 11  ? 15.335  -6.770  52.432  1.00 27.81  ? 11  GLN E CG  1 
ATOM   9247  C  CD  . GLN E 1 11  ? 15.072  -8.251  52.388  1.00 27.89  ? 11  GLN E CD  1 
ATOM   9248  O  OE1 . GLN E 1 11  ? 15.609  -8.982  51.539  1.00 25.88  ? 11  GLN E OE1 1 
ATOM   9249  N  NE2 . GLN E 1 11  ? 14.199  -8.705  53.271  1.00 28.90  ? 11  GLN E NE2 1 
ATOM   9250  N  N   . MET E 1 12  ? 15.073  -4.549  48.598  1.00 32.02  ? 12  MET E N   1 
ATOM   9251  C  CA  . MET E 1 12  ? 14.743  -4.033  47.288  1.00 35.37  ? 12  MET E CA  1 
ATOM   9252  C  C   . MET E 1 12  ? 13.405  -4.596  46.817  1.00 30.57  ? 12  MET E C   1 
ATOM   9253  O  O   . MET E 1 12  ? 13.293  -5.198  45.750  1.00 32.50  ? 12  MET E O   1 
ATOM   9254  C  CB  . MET E 1 12  ? 15.846  -4.367  46.280  1.00 47.99  ? 12  MET E CB  1 
ATOM   9255  C  CG  . MET E 1 12  ? 15.832  -3.429  45.042  1.00 65.28  ? 12  MET E CG  1 
ATOM   9256  S  SD  . MET E 1 12  ? 16.094  -1.665  45.370  1.00 67.59  ? 12  MET E SD  1 
ATOM   9257  C  CE  . MET E 1 12  ? 17.515  -1.667  46.491  1.00 62.18  ? 12  MET E CE  1 
ATOM   9258  N  N   . VAL E 1 13  ? 12.354  -4.301  47.565  1.00 28.76  ? 13  VAL E N   1 
ATOM   9259  C  CA  . VAL E 1 13  ? 11.059  -4.812  47.176  1.00 34.39  ? 13  VAL E CA  1 
ATOM   9260  C  C   . VAL E 1 13  ? 10.614  -4.116  45.913  1.00 40.46  ? 13  VAL E C   1 
ATOM   9261  O  O   . VAL E 1 13  ? 10.086  -4.783  45.034  1.00 38.15  ? 13  VAL E O   1 
ATOM   9262  C  CB  . VAL E 1 13  ? 10.036  -4.633  48.307  1.00 38.35  ? 13  VAL E CB  1 
ATOM   9263  C  CG1 . VAL E 1 13  ? 8.658   -5.000  47.813  1.00 40.52  ? 13  VAL E CG1 1 
ATOM   9264  C  CG2 . VAL E 1 13  ? 10.387  -5.511  49.501  1.00 41.54  ? 13  VAL E CG2 1 
ATOM   9265  N  N   . LEU E 1 14  ? 10.787  -2.780  45.908  1.00 43.75  ? 14  LEU E N   1 
ATOM   9266  C  CA  . LEU E 1 14  ? 10.464  -1.914  44.777  1.00 47.93  ? 14  LEU E CA  1 
ATOM   9267  C  C   . LEU E 1 14  ? 11.672  -1.955  43.841  1.00 41.49  ? 14  LEU E C   1 
ATOM   9268  O  O   . LEU E 1 14  ? 12.676  -1.284  43.982  1.00 42.55  ? 14  LEU E O   1 
ATOM   9269  C  CB  . LEU E 1 14  ? 10.142  -0.503  45.277  1.00 49.45  ? 14  LEU E CB  1 
ATOM   9270  C  CG  . LEU E 1 14  ? 9.276   -0.426  46.542  1.00 50.26  ? 14  LEU E CG  1 
ATOM   9271  C  CD1 . LEU E 1 14  ? 9.459   0.841   47.375  1.00 59.49  ? 14  LEU E CD1 1 
ATOM   9272  C  CD2 . LEU E 1 14  ? 7.828   -0.567  46.162  1.00 55.66  ? 14  LEU E CD2 1 
ATOM   9273  N  N   . SER E 1 15  ? 11.619  -2.841  42.883  1.00 47.16  ? 15  SER E N   1 
ATOM   9274  C  CA  . SER E 1 15  ? 12.740  -2.979  41.994  1.00 53.34  ? 15  SER E CA  1 
ATOM   9275  C  C   . SER E 1 15  ? 12.397  -2.272  40.679  1.00 57.03  ? 15  SER E C   1 
ATOM   9276  O  O   . SER E 1 15  ? 11.252  -2.195  40.237  1.00 44.34  ? 15  SER E O   1 
ATOM   9277  C  CB  . SER E 1 15  ? 13.092  -4.474  41.870  1.00 61.08  ? 15  SER E CB  1 
ATOM   9278  O  OG  . SER E 1 15  ? 13.690  -4.851  40.635  1.00 62.48  ? 15  SER E OG  1 
ATOM   9279  N  N   . PRO E 1 16  ? 13.398  -1.697  39.981  1.00 66.21  ? 16  PRO E N   1 
ATOM   9280  C  CA  . PRO E 1 16  ? 13.214  -1.410  38.554  1.00 54.87  ? 16  PRO E CA  1 
ATOM   9281  C  C   . PRO E 1 16  ? 12.583  -2.628  37.888  1.00 53.99  ? 16  PRO E C   1 
ATOM   9282  O  O   . PRO E 1 16  ? 12.659  -3.730  38.412  1.00 55.79  ? 16  PRO E O   1 
ATOM   9283  C  CB  . PRO E 1 16  ? 14.669  -1.210  38.043  1.00 59.48  ? 16  PRO E CB  1 
ATOM   9284  C  CG  . PRO E 1 16  ? 15.598  -1.536  39.253  1.00 58.52  ? 16  PRO E CG  1 
ATOM   9285  C  CD  . PRO E 1 16  ? 14.753  -1.398  40.509  1.00 59.02  ? 16  PRO E CD  1 
ATOM   9286  N  N   . LEU E 1 17  ? 12.057  -2.458  36.677  1.00 65.52  ? 17  LEU E N   1 
ATOM   9287  C  CA  . LEU E 1 17  ? 11.694  -3.573  35.803  1.00 60.99  ? 17  LEU E CA  1 
ATOM   9288  C  C   . LEU E 1 17  ? 12.938  -4.433  35.495  1.00 57.35  ? 17  LEU E C   1 
ATOM   9289  O  O   . LEU E 1 17  ? 14.037  -3.914  35.217  1.00 48.98  ? 17  LEU E O   1 
ATOM   9290  C  CB  . LEU E 1 17  ? 10.986  -3.044  34.550  1.00 74.91  ? 17  LEU E CB  1 
ATOM   9291  C  CG  . LEU E 1 17  ? 9.535   -2.551  34.737  1.00 77.44  ? 17  LEU E CG  1 
ATOM   9292  C  CD1 . LEU E 1 17  ? 9.016   -1.725  33.524  1.00 77.15  ? 17  LEU E CD1 1 
ATOM   9293  C  CD2 . LEU E 1 17  ? 8.605   -3.732  35.067  1.00 65.38  ? 17  LEU E CD2 1 
ATOM   9294  N  N   . THR E 1 18  ? 12.756  -5.755  35.670  1.00 38.86  ? 18  THR E N   1 
ATOM   9295  C  CA  . THR E 1 18  ? 13.808  -6.743  35.492  1.00 37.09  ? 18  THR E CA  1 
ATOM   9296  C  C   . THR E 1 18  ? 13.227  -7.842  34.616  1.00 32.68  ? 18  THR E C   1 
ATOM   9297  O  O   . THR E 1 18  ? 12.061  -8.141  34.661  1.00 39.21  ? 18  THR E O   1 
ATOM   9298  C  CB  . THR E 1 18  ? 14.317  -7.299  36.839  1.00 38.31  ? 18  THR E CB  1 
ATOM   9299  O  OG1 . THR E 1 18  ? 13.208  -7.704  37.650  1.00 38.81  ? 18  THR E OG1 1 
ATOM   9300  C  CG2 . THR E 1 18  ? 15.137  -6.332  37.672  1.00 34.12  ? 18  THR E CG2 1 
ATOM   9301  N  N   . SER E 1 19  ? 14.037  -8.523  33.845  1.00 30.55  ? 19  SER E N   1 
ATOM   9302  C  CA  . SER E 1 19  ? 13.504  -9.416  32.841  1.00 30.61  ? 19  SER E CA  1 
ATOM   9303  C  C   . SER E 1 19  ? 13.786  -10.868 33.226  1.00 28.39  ? 19  SER E C   1 
ATOM   9304  O  O   . SER E 1 19  ? 13.323  -11.800 32.565  1.00 27.94  ? 19  SER E O   1 
ATOM   9305  C  CB  . SER E 1 19  ? 14.087  -9.031  31.486  1.00 29.46  ? 19  SER E CB  1 
ATOM   9306  O  OG  . SER E 1 19  ? 15.289  -8.301  31.694  1.00 33.31  ? 19  SER E OG  1 
ATOM   9307  N  N   . ALA E 1 20  ? 14.553  -11.093 34.292  1.00 24.13  ? 20  ALA E N   1 
ATOM   9308  C  CA  . ALA E 1 20  ? 14.846  -12.465 34.695  1.00 20.27  ? 20  ALA E CA  1 
ATOM   9309  C  C   . ALA E 1 20  ? 14.694  -12.581 36.200  1.00 20.12  ? 20  ALA E C   1 
ATOM   9310  O  O   . ALA E 1 20  ? 14.889  -11.601 36.916  1.00 18.11  ? 20  ALA E O   1 
ATOM   9311  C  CB  . ALA E 1 20  ? 16.231  -12.815 34.292  1.00 18.84  ? 20  ALA E CB  1 
ATOM   9312  N  N   . ALA E 1 21  ? 14.376  -13.789 36.658  1.00 19.89  ? 21  ALA E N   1 
ATOM   9313  C  CA  . ALA E 1 21  ? 14.243  -14.002 38.083  1.00 20.17  ? 21  ALA E CA  1 
ATOM   9314  C  C   . ALA E 1 21  ? 14.523  -15.436 38.384  1.00 18.81  ? 21  ALA E C   1 
ATOM   9315  O  O   . ALA E 1 21  ? 14.239  -16.289 37.575  1.00 18.28  ? 21  ALA E O   1 
ATOM   9316  C  CB  . ALA E 1 21  ? 12.854  -13.672 38.586  1.00 20.70  ? 21  ALA E CB  1 
ATOM   9317  N  N   . ILE E 1 22  ? 14.967  -15.652 39.612  1.00 19.72  ? 22  ILE E N   1 
ATOM   9318  C  CA  . ILE E 1 22  ? 14.970  -16.971 40.195  1.00 21.29  ? 22  ILE E CA  1 
ATOM   9319  C  C   . ILE E 1 22  ? 14.195  -16.873 41.500  1.00 21.54  ? 22  ILE E C   1 
ATOM   9320  O  O   . ILE E 1 22  ? 14.438  -15.992 42.285  1.00 21.04  ? 22  ILE E O   1 
ATOM   9321  C  CB  . ILE E 1 22  ? 16.399  -17.507 40.400  1.00 22.66  ? 22  ILE E CB  1 
ATOM   9322  C  CG1 . ILE E 1 22  ? 17.040  -17.857 39.084  1.00 21.11  ? 22  ILE E CG1 1 
ATOM   9323  C  CG2 . ILE E 1 22  ? 16.351  -18.720 41.342  1.00 24.68  ? 22  ILE E CG2 1 
ATOM   9324  C  CD1 . ILE E 1 22  ? 18.437  -18.424 39.198  1.00 21.64  ? 22  ILE E CD1 1 
ATOM   9325  N  N   . PHE E 1 23  ? 13.242  -17.788 41.680  1.00 23.17  ? 23  PHE E N   1 
ATOM   9326  C  CA  . PHE E 1 23  ? 12.537  -17.948 42.952  1.00 23.77  ? 23  PHE E CA  1 
ATOM   9327  C  C   . PHE E 1 23  ? 12.983  -19.257 43.581  1.00 20.76  ? 23  PHE E C   1 
ATOM   9328  O  O   . PHE E 1 23  ? 12.943  -20.315 42.972  1.00 19.31  ? 23  PHE E O   1 
ATOM   9329  C  CB  . PHE E 1 23  ? 11.022  -18.015 42.807  1.00 23.27  ? 23  PHE E CB  1 
ATOM   9330  C  CG  . PHE E 1 23  ? 10.418  -16.845 42.064  1.00 21.48  ? 23  PHE E CG  1 
ATOM   9331  C  CD1 . PHE E 1 23  ? 10.334  -16.833 40.685  1.00 25.48  ? 23  PHE E CD1 1 
ATOM   9332  C  CD2 . PHE E 1 23  ? 9.900   -15.790 42.748  1.00 21.88  ? 23  PHE E CD2 1 
ATOM   9333  C  CE1 . PHE E 1 23  ? 9.805   -15.734 40.009  1.00 26.97  ? 23  PHE E CE1 1 
ATOM   9334  C  CE2 . PHE E 1 23  ? 9.307   -14.744 42.066  1.00 24.19  ? 23  PHE E CE2 1 
ATOM   9335  C  CZ  . PHE E 1 23  ? 9.302   -14.695 40.695  1.00 22.23  ? 23  PHE E CZ  1 
ATOM   9336  N  N   . LEU E 1 24  ? 13.482  -19.128 44.792  1.00 20.05  ? 24  LEU E N   1 
ATOM   9337  C  CA  . LEU E 1 24  ? 13.938  -20.262 45.551  1.00 22.14  ? 24  LEU E CA  1 
ATOM   9338  C  C   . LEU E 1 24  ? 13.142  -20.360 46.843  1.00 20.44  ? 24  LEU E C   1 
ATOM   9339  O  O   . LEU E 1 24  ? 13.042  -19.392 47.603  1.00 23.87  ? 24  LEU E O   1 
ATOM   9340  C  CB  . LEU E 1 24  ? 15.376  -19.893 45.810  1.00 27.19  ? 24  LEU E CB  1 
ATOM   9341  C  CG  . LEU E 1 24  ? 16.323  -21.044 46.051  1.00 38.01  ? 24  LEU E CG  1 
ATOM   9342  C  CD1 . LEU E 1 24  ? 16.503  -21.760 44.706  1.00 40.98  ? 24  LEU E CD1 1 
ATOM   9343  C  CD2 . LEU E 1 24  ? 17.609  -20.408 46.515  1.00 49.27  ? 24  LEU E CD2 1 
ATOM   9344  N  N   . VAL E 1 25  ? 12.500  -21.506 47.077  1.00 21.25  ? 25  VAL E N   1 
ATOM   9345  C  CA  . VAL E 1 25  ? 11.826  -21.753 48.339  1.00 20.32  ? 25  VAL E CA  1 
ATOM   9346  C  C   . VAL E 1 25  ? 12.446  -22.962 48.994  1.00 20.50  ? 25  VAL E C   1 
ATOM   9347  O  O   . VAL E 1 25  ? 12.520  -24.006 48.377  1.00 23.85  ? 25  VAL E O   1 
ATOM   9348  C  CB  . VAL E 1 25  ? 10.321  -21.907 48.197  1.00 23.64  ? 25  VAL E CB  1 
ATOM   9349  C  CG1 . VAL E 1 25  ? 9.685   -22.197 49.549  1.00 26.10  ? 25  VAL E CG1 1 
ATOM   9350  C  CG2 . VAL E 1 25  ? 9.669   -20.646 47.609  1.00 25.54  ? 25  VAL E CG2 1 
ATOM   9351  N  N   . VAL E 1 26  ? 12.947  -22.801 50.214  1.00 21.99  ? 26  VAL E N   1 
ATOM   9352  C  CA  . VAL E 1 26  ? 13.550  -23.929 50.933  1.00 26.60  ? 26  VAL E CA  1 
ATOM   9353  C  C   . VAL E 1 26  ? 12.899  -24.087 52.319  1.00 23.51  ? 26  VAL E C   1 
ATOM   9354  O  O   . VAL E 1 26  ? 12.308  -23.142 52.866  1.00 20.40  ? 26  VAL E O   1 
ATOM   9355  C  CB  . VAL E 1 26  ? 15.079  -23.733 51.059  1.00 23.19  ? 26  VAL E CB  1 
ATOM   9356  C  CG1 . VAL E 1 26  ? 15.686  -23.538 49.672  1.00 24.74  ? 26  VAL E CG1 1 
ATOM   9357  C  CG2 . VAL E 1 26  ? 15.419  -22.564 51.974  1.00 19.85  ? 26  VAL E CG2 1 
ATOM   9358  N  N   . THR E 1 27  ? 13.038  -25.305 52.869  1.00 22.91  ? 27  THR E N   1 
ATOM   9359  C  CA  . THR E 1 27  ? 12.766  -25.528 54.294  1.00 23.56  ? 27  THR E CA  1 
ATOM   9360  C  C   . THR E 1 27  ? 14.059  -25.764 55.059  1.00 23.30  ? 27  THR E C   1 
ATOM   9361  O  O   . THR E 1 27  ? 15.025  -26.288 54.496  1.00 28.61  ? 27  THR E O   1 
ATOM   9362  C  CB  . THR E 1 27  ? 11.784  -26.677 54.490  1.00 21.98  ? 27  THR E CB  1 
ATOM   9363  O  OG1 . THR E 1 27  ? 12.328  -27.798 53.835  1.00 21.34  ? 27  THR E OG1 1 
ATOM   9364  C  CG2 . THR E 1 27  ? 10.421  -26.303 53.959  1.00 23.50  ? 27  THR E CG2 1 
ATOM   9365  N  N   . ILE E 1 28  ? 14.055  -25.353 56.327  1.00 20.08  ? 28  ILE E N   1 
ATOM   9366  C  CA  . ILE E 1 28  ? 15.204  -25.493 57.205  1.00 20.55  ? 28  ILE E CA  1 
ATOM   9367  C  C   . ILE E 1 28  ? 15.205  -26.821 57.935  1.00 23.22  ? 28  ILE E C   1 
ATOM   9368  O  O   . ILE E 1 28  ? 14.293  -27.180 58.701  1.00 25.12  ? 28  ILE E O   1 
ATOM   9369  C  CB  . ILE E 1 28  ? 15.225  -24.348 58.202  1.00 23.02  ? 28  ILE E CB  1 
ATOM   9370  C  CG1 . ILE E 1 28  ? 15.131  -22.977 57.541  1.00 24.04  ? 28  ILE E CG1 1 
ATOM   9371  C  CG2 . ILE E 1 28  ? 16.460  -24.473 59.055  1.00 26.32  ? 28  ILE E CG2 1 
ATOM   9372  C  CD1 . ILE E 1 28  ? 14.797  -21.889 58.548  1.00 26.72  ? 28  ILE E CD1 1 
ATOM   9373  N  N   . ASP E 1 29  ? 16.262  -27.587 57.704  1.00 24.92  ? 29  ASP E N   1 
ATOM   9374  C  CA  . ASP E 1 29  ? 16.374  -28.917 58.303  1.00 25.14  ? 29  ASP E CA  1 
ATOM   9375  C  C   . ASP E 1 29  ? 16.632  -28.807 59.798  1.00 21.45  ? 29  ASP E C   1 
ATOM   9376  O  O   . ASP E 1 29  ? 16.987  -27.749 60.297  1.00 21.38  ? 29  ASP E O   1 
ATOM   9377  C  CB  . ASP E 1 29  ? 17.499  -29.741 57.698  1.00 26.36  ? 29  ASP E CB  1 
ATOM   9378  C  CG  . ASP E 1 29  ? 17.338  -30.058 56.234  1.00 29.07  ? 29  ASP E CG  1 
ATOM   9379  O  OD1 . ASP E 1 29  ? 16.252  -29.703 55.645  1.00 31.44  ? 29  ASP E OD1 1 
ATOM   9380  O  OD2 . ASP E 1 29  ? 18.278  -30.663 55.763  1.00 28.37  ? 29  ASP E OD2 1 
ATOM   9381  N  N   . SER E 1 30  ? 16.553  -29.972 60.460  1.00 21.39  ? 30  SER E N   1 
ATOM   9382  C  CA  . SER E 1 30  ? 16.858  -30.062 61.870  1.00 23.07  ? 30  SER E CA  1 
ATOM   9383  C  C   . SER E 1 30  ? 18.266  -29.581 62.066  1.00 22.35  ? 30  SER E C   1 
ATOM   9384  O  O   . SER E 1 30  ? 19.134  -30.102 61.404  1.00 21.45  ? 30  SER E O   1 
ATOM   9385  C  CB  . SER E 1 30  ? 16.767  -31.469 62.334  1.00 26.32  ? 30  SER E CB  1 
ATOM   9386  O  OG  . SER E 1 30  ? 15.474  -31.988 62.015  1.00 36.01  ? 30  SER E OG  1 
ATOM   9387  N  N   . GLY E 1 31  ? 18.495  -28.652 62.976  1.00 24.07  ? 31  GLY E N   1 
ATOM   9388  C  CA  . GLY E 1 31  ? 19.858  -28.249 63.252  1.00 25.53  ? 31  GLY E CA  1 
ATOM   9389  C  C   . GLY E 1 31  ? 20.329  -27.118 62.349  1.00 29.30  ? 31  GLY E C   1 
ATOM   9390  O  O   . GLY E 1 31  ? 21.454  -26.664 62.525  1.00 35.50  ? 31  GLY E O   1 
ATOM   9391  N  N   . GLY E 1 32  ? 19.482  -26.637 61.422  1.00 26.24  ? 32  GLY E N   1 
ATOM   9392  C  CA  . GLY E 1 32  ? 19.977  -25.749 60.379  1.00 25.47  ? 32  GLY E CA  1 
ATOM   9393  C  C   . GLY E 1 32  ? 19.996  -24.267 60.759  1.00 28.01  ? 32  GLY E C   1 
ATOM   9394  O  O   . GLY E 1 32  ? 20.513  -23.449 59.996  1.00 26.69  ? 32  GLY E O   1 
ATOM   9395  N  N   . GLU E 1 33  ? 19.413  -23.920 61.922  1.00 26.65  ? 33  GLU E N   1 
ATOM   9396  C  CA  . GLU E 1 33  ? 19.102  -22.541 62.237  1.00 23.35  ? 33  GLU E CA  1 
ATOM   9397  C  C   . GLU E 1 33  ? 20.375  -21.684 62.287  1.00 27.39  ? 33  GLU E C   1 
ATOM   9398  O  O   . GLU E 1 33  ? 20.354  -20.493 61.968  1.00 27.21  ? 33  GLU E O   1 
ATOM   9399  C  CB  . GLU E 1 33  ? 18.356  -22.406 63.576  1.00 26.15  ? 33  GLU E CB  1 
ATOM   9400  C  CG  . GLU E 1 33  ? 17.001  -23.069 63.728  1.00 26.27  ? 33  GLU E CG  1 
ATOM   9401  C  CD  . GLU E 1 33  ? 16.983  -24.558 63.979  1.00 29.93  ? 33  GLU E CD  1 
ATOM   9402  O  OE1 . GLU E 1 33  ? 18.009  -25.282 64.013  1.00 30.42  ? 33  GLU E OE1 1 
ATOM   9403  O  OE2 . GLU E 1 33  ? 15.837  -25.005 64.048  1.00 31.15  ? 33  GLU E OE2 1 
ATOM   9404  N  N   . ASP E 1 34  ? 21.492  -22.213 62.798  1.00 30.88  ? 34  ASP E N   1 
ATOM   9405  C  CA  . ASP E 1 34  ? 22.673  -21.393 62.967  1.00 32.09  ? 34  ASP E CA  1 
ATOM   9406  C  C   . ASP E 1 34  ? 23.252  -21.032 61.606  1.00 28.83  ? 34  ASP E C   1 
ATOM   9407  O  O   . ASP E 1 34  ? 23.631  -19.887 61.362  1.00 29.86  ? 34  ASP E O   1 
ATOM   9408  C  CB  . ASP E 1 34  ? 23.725  -22.182 63.723  1.00 35.96  ? 34  ASP E CB  1 
ATOM   9409  C  CG  . ASP E 1 34  ? 23.589  -22.104 65.222  1.00 37.96  ? 34  ASP E CG  1 
ATOM   9410  O  OD1 . ASP E 1 34  ? 23.160  -21.058 65.701  1.00 38.07  ? 34  ASP E OD1 1 
ATOM   9411  O  OD2 . ASP E 1 34  ? 24.012  -23.039 65.853  1.00 41.14  ? 34  ASP E OD2 1 
ATOM   9412  N  N   . THR E 1 35  ? 23.376  -22.045 60.742  1.00 24.51  ? 35  THR E N   1 
ATOM   9413  C  CA  . THR E 1 35  ? 23.848  -21.800 59.401  1.00 23.91  ? 35  THR E CA  1 
ATOM   9414  C  C   . THR E 1 35  ? 22.981  -20.763 58.693  1.00 26.94  ? 35  THR E C   1 
ATOM   9415  O  O   . THR E 1 35  ? 23.496  -19.881 58.019  1.00 24.56  ? 35  THR E O   1 
ATOM   9416  C  CB  . THR E 1 35  ? 23.816  -23.102 58.651  1.00 26.20  ? 35  THR E CB  1 
ATOM   9417  O  OG1 . THR E 1 35  ? 24.796  -23.888 59.302  1.00 28.85  ? 35  THR E OG1 1 
ATOM   9418  C  CG2 . THR E 1 35  ? 24.267  -22.939 57.228  1.00 27.03  ? 35  THR E CG2 1 
ATOM   9419  N  N   . VAL E 1 36  ? 21.654  -20.866 58.851  1.00 23.87  ? 36  VAL E N   1 
ATOM   9420  C  CA  . VAL E 1 36  ? 20.745  -19.933 58.226  1.00 22.34  ? 36  VAL E CA  1 
ATOM   9421  C  C   . VAL E 1 36  ? 20.989  -18.555 58.775  1.00 21.77  ? 36  VAL E C   1 
ATOM   9422  O  O   . VAL E 1 36  ? 21.048  -17.615 58.035  1.00 26.19  ? 36  VAL E O   1 
ATOM   9423  C  CB  . VAL E 1 36  ? 19.275  -20.369 58.415  1.00 20.87  ? 36  VAL E CB  1 
ATOM   9424  C  CG1 . VAL E 1 36  ? 18.253  -19.306 58.061  1.00 19.82  ? 36  VAL E CG1 1 
ATOM   9425  C  CG2 . VAL E 1 36  ? 18.995  -21.614 57.608  1.00 20.48  ? 36  VAL E CG2 1 
ATOM   9426  N  N   . ARG E 1 37  ? 21.077  -18.399 60.066  1.00 23.94  ? 37  ARG E N   1 
ATOM   9427  C  CA  . ARG E 1 37  ? 21.246  -17.066 60.599  1.00 24.57  ? 37  ARG E CA  1 
ATOM   9428  C  C   . ARG E 1 37  ? 22.546  -16.431 60.121  1.00 24.80  ? 37  ARG E C   1 
ATOM   9429  O  O   . ARG E 1 37  ? 22.549  -15.239 59.916  1.00 25.24  ? 37  ARG E O   1 
ATOM   9430  C  CB  . ARG E 1 37  ? 21.337  -17.116 62.118  1.00 31.10  ? 37  ARG E CB  1 
ATOM   9431  C  CG  . ARG E 1 37  ? 20.023  -16.851 62.824  1.00 44.65  ? 37  ARG E CG  1 
ATOM   9432  C  CD  . ARG E 1 37  ? 20.194  -16.414 64.311  1.00 49.83  ? 37  ARG E CD  1 
ATOM   9433  N  NE  . ARG E 1 37  ? 20.587  -17.659 64.983  1.00 53.14  ? 37  ARG E NE  1 
ATOM   9434  C  CZ  . ARG E 1 37  ? 19.819  -18.735 65.210  1.00 57.48  ? 37  ARG E CZ  1 
ATOM   9435  N  NH1 . ARG E 1 37  ? 18.502  -18.627 65.342  1.00 60.33  ? 37  ARG E NH1 1 
ATOM   9436  N  NH2 . ARG E 1 37  ? 20.394  -19.925 65.363  1.00 57.62  ? 37  ARG E NH2 1 
ATOM   9437  N  N   . ASP E 1 38  ? 23.646  -17.177 59.986  1.00 27.27  ? 38  ASP E N   1 
ATOM   9438  C  CA  . ASP E 1 38  ? 24.853  -16.622 59.395  1.00 32.78  ? 38  ASP E CA  1 
ATOM   9439  C  C   . ASP E 1 38  ? 24.597  -16.108 57.968  1.00 33.77  ? 38  ASP E C   1 
ATOM   9440  O  O   . ASP E 1 38  ? 25.025  -15.006 57.615  1.00 27.73  ? 38  ASP E O   1 
ATOM   9441  C  CB  . ASP E 1 38  ? 26.008  -17.593 59.207  1.00 40.15  ? 38  ASP E CB  1 
ATOM   9442  C  CG  . ASP E 1 38  ? 26.822  -17.909 60.454  1.00 57.93  ? 38  ASP E CG  1 
ATOM   9443  O  OD1 . ASP E 1 38  ? 26.683  -17.194 61.474  1.00 59.50  ? 38  ASP E OD1 1 
ATOM   9444  O  OD2 . ASP E 1 38  ? 27.557  -18.917 60.434  1.00 72.21  ? 38  ASP E OD2 1 
ATOM   9445  N  N   . LEU E 1 39  ? 23.939  -16.919 57.125  1.00 29.42  ? 39  LEU E N   1 
ATOM   9446  C  CA  . LEU E 1 39  ? 23.702  -16.509 55.756  1.00 25.14  ? 39  LEU E CA  1 
ATOM   9447  C  C   . LEU E 1 39  ? 22.800  -15.261 55.707  1.00 25.48  ? 39  LEU E C   1 
ATOM   9448  O  O   . LEU E 1 39  ? 22.997  -14.351 54.891  1.00 24.63  ? 39  LEU E O   1 
ATOM   9449  C  CB  . LEU E 1 39  ? 23.139  -17.730 55.043  1.00 29.54  ? 39  LEU E CB  1 
ATOM   9450  C  CG  . LEU E 1 39  ? 22.637  -17.570 53.591  1.00 34.63  ? 39  LEU E CG  1 
ATOM   9451  C  CD1 . LEU E 1 39  ? 21.360  -16.776 53.371  1.00 33.28  ? 39  LEU E CD1 1 
ATOM   9452  C  CD2 . LEU E 1 39  ? 23.670  -16.870 52.746  1.00 37.54  ? 39  LEU E CD2 1 
ATOM   9453  N  N   . LEU E 1 40  ? 21.796  -15.165 56.590  1.00 24.08  ? 40  LEU E N   1 
ATOM   9454  C  CA  . LEU E 1 40  ? 20.923  -14.020 56.532  1.00 26.03  ? 40  LEU E CA  1 
ATOM   9455  C  C   . LEU E 1 40  ? 21.718  -12.739 56.795  1.00 26.07  ? 40  LEU E C   1 
ATOM   9456  O  O   . LEU E 1 40  ? 21.389  -11.642 56.314  1.00 24.39  ? 40  LEU E O   1 
ATOM   9457  C  CB  . LEU E 1 40  ? 19.793  -14.197 57.549  1.00 31.63  ? 40  LEU E CB  1 
ATOM   9458  C  CG  . LEU E 1 40  ? 18.787  -15.316 57.276  1.00 32.47  ? 40  LEU E CG  1 
ATOM   9459  C  CD1 . LEU E 1 40  ? 17.771  -15.337 58.392  1.00 38.49  ? 40  LEU E CD1 1 
ATOM   9460  C  CD2 . LEU E 1 40  ? 18.105  -15.104 55.968  1.00 32.26  ? 40  LEU E CD2 1 
ATOM   9461  N  N   . SER E 1 41  ? 22.694  -12.830 57.683  1.00 25.49  ? 41  SER E N   1 
ATOM   9462  C  CA  . SER E 1 41  ? 23.392  -11.595 58.039  1.00 36.51  ? 41  SER E CA  1 
ATOM   9463  C  C   . SER E 1 41  ? 24.357  -11.153 56.922  1.00 34.09  ? 41  SER E C   1 
ATOM   9464  O  O   . SER E 1 41  ? 24.775  -10.016 56.891  1.00 27.91  ? 41  SER E O   1 
ATOM   9465  C  CB  . SER E 1 41  ? 24.130  -11.719 59.356  1.00 38.13  ? 41  SER E CB  1 
ATOM   9466  O  OG  . SER E 1 41  ? 25.250  -12.577 59.183  1.00 39.14  ? 41  SER E OG  1 
ATOM   9467  N  N   . ASP E 1 42  ? 24.681  -12.042 55.980  1.00 33.07  ? 42  ASP E N   1 
ATOM   9468  C  CA  . ASP E 1 42  ? 25.614  -11.724 54.913  1.00 29.11  ? 42  ASP E CA  1 
ATOM   9469  C  C   . ASP E 1 42  ? 24.937  -11.556 53.541  1.00 32.58  ? 42  ASP E C   1 
ATOM   9470  O  O   . ASP E 1 42  ? 25.608  -11.309 52.542  1.00 25.72  ? 42  ASP E O   1 
ATOM   9471  C  CB  . ASP E 1 42  ? 26.569  -12.880 54.775  1.00 28.38  ? 42  ASP E CB  1 
ATOM   9472  C  CG  . ASP E 1 42  ? 27.674  -12.993 55.813  1.00 34.49  ? 42  ASP E CG  1 
ATOM   9473  O  OD1 . ASP E 1 42  ? 27.965  -12.024 56.580  1.00 41.18  ? 42  ASP E OD1 1 
ATOM   9474  O  OD2 . ASP E 1 42  ? 28.224  -14.104 55.887  1.00 36.84  ? 42  ASP E OD2 1 
ATOM   9475  N  N   . VAL E 1 43  ? 23.609  -11.769 53.438  1.00 35.48  ? 43  VAL E N   1 
ATOM   9476  C  CA  . VAL E 1 43  ? 23.005  -11.907 52.115  1.00 33.74  ? 43  VAL E CA  1 
ATOM   9477  C  C   . VAL E 1 43  ? 23.086  -10.549 51.382  1.00 27.05  ? 43  VAL E C   1 
ATOM   9478  O  O   . VAL E 1 43  ? 23.299  -10.541 50.171  1.00 21.63  ? 43  VAL E O   1 
ATOM   9479  C  CB  . VAL E 1 43  ? 21.582  -12.514 52.186  1.00 34.00  ? 43  VAL E CB  1 
ATOM   9480  C  CG1 . VAL E 1 43  ? 20.603  -11.495 52.742  1.00 36.34  ? 43  VAL E CG1 1 
ATOM   9481  C  CG2 . VAL E 1 43  ? 21.076  -12.980 50.845  1.00 35.13  ? 43  VAL E CG2 1 
ATOM   9482  N  N   . ALA E 1 44  ? 22.973  -9.397  52.079  1.00 26.76  ? 44  ALA E N   1 
ATOM   9483  C  CA  . ALA E 1 44  ? 23.168  -8.112  51.394  1.00 28.58  ? 44  ALA E CA  1 
ATOM   9484  C  C   . ALA E 1 44  ? 24.591  -7.983  50.814  1.00 30.08  ? 44  ALA E C   1 
ATOM   9485  O  O   . ALA E 1 44  ? 24.775  -7.472  49.685  1.00 25.75  ? 44  ALA E O   1 
ATOM   9486  C  CB  . ALA E 1 44  ? 22.863  -6.979  52.279  1.00 24.86  ? 44  ALA E CB  1 
ATOM   9487  N  N   . SER E 1 45  ? 25.609  -8.486  51.544  1.00 29.14  ? 45  SER E N   1 
ATOM   9488  C  CA  . SER E 1 45  ? 26.945  -8.300  50.995  1.00 28.47  ? 45  SER E CA  1 
ATOM   9489  C  C   . SER E 1 45  ? 27.191  -9.255  49.852  1.00 27.20  ? 45  SER E C   1 
ATOM   9490  O  O   . SER E 1 45  ? 27.967  -8.895  48.957  1.00 28.76  ? 45  SER E O   1 
ATOM   9491  C  CB  . SER E 1 45  ? 28.086  -8.268  51.965  1.00 30.95  ? 45  SER E CB  1 
ATOM   9492  O  OG  . SER E 1 45  ? 28.028  -9.438  52.703  1.00 36.44  ? 45  SER E OG  1 
ATOM   9493  N  N   . LEU E 1 46  ? 26.525  -10.416 49.825  1.00 27.56  ? 46  LEU E N   1 
ATOM   9494  C  CA  . LEU E 1 46  ? 26.630  -11.296 48.650  1.00 26.60  ? 46  LEU E CA  1 
ATOM   9495  C  C   . LEU E 1 46  ? 25.944  -10.669 47.421  1.00 26.08  ? 46  LEU E C   1 
ATOM   9496  O  O   . LEU E 1 46  ? 26.415  -10.777 46.304  1.00 30.27  ? 46  LEU E O   1 
ATOM   9497  C  CB  . LEU E 1 46  ? 26.023  -12.646 49.028  1.00 26.29  ? 46  LEU E CB  1 
ATOM   9498  C  CG  . LEU E 1 46  ? 26.835  -13.431 50.048  1.00 26.14  ? 46  LEU E CG  1 
ATOM   9499  C  CD1 . LEU E 1 46  ? 26.107  -14.679 50.327  1.00 30.94  ? 46  LEU E CD1 1 
ATOM   9500  C  CD2 . LEU E 1 46  ? 28.188  -13.818 49.459  1.00 25.12  ? 46  LEU E CD2 1 
ATOM   9501  N  N   . GLU E 1 47  ? 24.829  -9.971  47.629  1.00 25.36  ? 47  GLU E N   1 
ATOM   9502  C  CA  . GLU E 1 47  ? 24.160  -9.287  46.561  1.00 27.89  ? 47  GLU E CA  1 
ATOM   9503  C  C   . GLU E 1 47  ? 25.120  -8.250  45.956  1.00 26.09  ? 47  GLU E C   1 
ATOM   9504  O  O   . GLU E 1 47  ? 25.235  -8.158  44.738  1.00 28.50  ? 47  GLU E O   1 
ATOM   9505  C  CB  . GLU E 1 47  ? 22.868  -8.704  47.136  1.00 30.03  ? 47  GLU E CB  1 
ATOM   9506  C  CG  . GLU E 1 47  ? 22.018  -7.924  46.138  1.00 32.63  ? 47  GLU E CG  1 
ATOM   9507  C  CD  . GLU E 1 47  ? 20.986  -7.138  46.896  1.00 41.30  ? 47  GLU E CD  1 
ATOM   9508  O  OE1 . GLU E 1 47  ? 21.336  -6.160  47.566  1.00 61.55  ? 47  GLU E OE1 1 
ATOM   9509  O  OE2 . GLU E 1 47  ? 19.819  -7.528  46.870  1.00 49.45  ? 47  GLU E OE2 1 
ATOM   9510  N  N   . ARG E 1 48  ? 25.813  -7.467  46.787  1.00 25.15  ? 48  ARG E N   1 
ATOM   9511  C  CA  . ARG E 1 48  ? 26.770  -6.525  46.227  1.00 27.65  ? 48  ARG E CA  1 
ATOM   9512  C  C   . ARG E 1 48  ? 27.996  -7.195  45.584  1.00 28.60  ? 48  ARG E C   1 
ATOM   9513  O  O   . ARG E 1 48  ? 28.462  -6.746  44.549  1.00 29.86  ? 48  ARG E O   1 
ATOM   9514  C  CB  . ARG E 1 48  ? 27.285  -5.584  47.296  1.00 29.02  ? 48  ARG E CB  1 
ATOM   9515  C  CG  . ARG E 1 48  ? 26.149  -4.680  47.705  1.00 35.42  ? 48  ARG E CG  1 
ATOM   9516  C  CD  . ARG E 1 48  ? 26.713  -3.543  48.530  1.00 48.83  ? 48  ARG E CD  1 
ATOM   9517  N  NE  . ARG E 1 48  ? 27.368  -3.971  49.784  1.00 51.19  ? 48  ARG E NE  1 
ATOM   9518  C  CZ  . ARG E 1 48  ? 26.753  -4.267  50.938  1.00 42.54  ? 48  ARG E CZ  1 
ATOM   9519  N  NH1 . ARG E 1 48  ? 25.444  -4.162  51.061  1.00 40.47  ? 48  ARG E NH1 1 
ATOM   9520  N  NH2 . ARG E 1 48  ? 27.441  -4.672  51.981  1.00 42.33  ? 48  ARG E NH2 1 
ATOM   9521  N  N   . ALA E 1 49  ? 28.535  -8.260  46.174  1.00 24.33  ? 49  ALA E N   1 
ATOM   9522  C  CA  . ALA E 1 49  ? 29.653  -8.939  45.560  1.00 26.85  ? 49  ALA E CA  1 
ATOM   9523  C  C   . ALA E 1 49  ? 29.368  -9.421  44.145  1.00 27.23  ? 49  ALA E C   1 
ATOM   9524  O  O   . ALA E 1 49  ? 30.171  -9.235  43.224  1.00 35.35  ? 49  ALA E O   1 
ATOM   9525  C  CB  . ALA E 1 49  ? 30.059  -10.115 46.409  1.00 28.32  ? 49  ALA E CB  1 
ATOM   9526  N  N   . VAL E 1 50  ? 28.215  -10.052 43.982  1.00 26.57  ? 50  VAL E N   1 
ATOM   9527  C  CA  . VAL E 1 50  ? 27.844  -10.604 42.689  1.00 29.00  ? 50  VAL E CA  1 
ATOM   9528  C  C   . VAL E 1 50  ? 27.430  -9.478  41.723  1.00 28.43  ? 50  VAL E C   1 
ATOM   9529  O  O   . VAL E 1 50  ? 27.676  -9.539  40.531  1.00 32.57  ? 50  VAL E O   1 
ATOM   9530  C  CB  . VAL E 1 50  ? 26.742  -11.675 42.847  1.00 26.66  ? 50  VAL E CB  1 
ATOM   9531  C  CG1 . VAL E 1 50  ? 26.284  -12.183 41.505  1.00 29.44  ? 50  VAL E CG1 1 
ATOM   9532  C  CG2 . VAL E 1 50  ? 27.223  -12.834 43.697  1.00 24.04  ? 50  VAL E CG2 1 
ATOM   9533  N  N   . GLY E 1 51  ? 26.805  -8.431  42.222  1.00 26.43  ? 51  GLY E N   1 
ATOM   9534  C  CA  . GLY E 1 51  ? 26.150  -7.505  41.337  1.00 25.87  ? 51  GLY E CA  1 
ATOM   9535  C  C   . GLY E 1 51  ? 26.992  -6.272  41.020  1.00 29.08  ? 51  GLY E C   1 
ATOM   9536  O  O   . GLY E 1 51  ? 26.785  -5.649  39.985  1.00 31.35  ? 51  GLY E O   1 
ATOM   9537  N  N   . PHE E 1 52  ? 27.889  -5.822  41.903  1.00 26.63  ? 52  PHE E N   1 
ATOM   9538  C  CA  . PHE E 1 52  ? 28.458  -4.494  41.717  1.00 23.54  ? 52  PHE E CA  1 
ATOM   9539  C  C   . PHE E 1 52  ? 29.248  -4.460  40.428  1.00 26.18  ? 52  PHE E C   1 
ATOM   9540  O  O   . PHE E 1 52  ? 29.124  -3.533  39.670  1.00 30.24  ? 52  PHE E O   1 
ATOM   9541  C  CB  . PHE E 1 52  ? 29.384  -4.185  42.871  1.00 27.96  ? 52  PHE E CB  1 
ATOM   9542  C  CG  . PHE E 1 52  ? 30.042  -2.847  42.627  1.00 28.48  ? 52  PHE E CG  1 
ATOM   9543  C  CD1 . PHE E 1 52  ? 29.356  -1.677  42.853  1.00 28.70  ? 52  PHE E CD1 1 
ATOM   9544  C  CD2 . PHE E 1 52  ? 31.355  -2.782  42.192  1.00 29.78  ? 52  PHE E CD2 1 
ATOM   9545  C  CE1 . PHE E 1 52  ? 29.943  -0.473  42.577  1.00 30.41  ? 52  PHE E CE1 1 
ATOM   9546  C  CE2 . PHE E 1 52  ? 31.963  -1.562  42.003  1.00 29.19  ? 52  PHE E CE2 1 
ATOM   9547  C  CZ  . PHE E 1 52  ? 31.237  -0.424  42.146  1.00 28.21  ? 52  PHE E CZ  1 
ATOM   9548  N  N   . ARG E 1 53  ? 30.007  -5.523  40.129  1.00 34.09  ? 53  ARG E N   1 
ATOM   9549  C  CA  . ARG E 1 53  ? 30.864  -5.528  38.968  1.00 35.38  ? 53  ARG E CA  1 
ATOM   9550  C  C   . ARG E 1 53  ? 30.041  -5.486  37.672  1.00 36.02  ? 53  ARG E C   1 
ATOM   9551  O  O   . ARG E 1 53  ? 30.625  -5.210  36.623  1.00 33.35  ? 53  ARG E O   1 
ATOM   9552  C  CB  . ARG E 1 53  ? 31.908  -6.653  39.061  1.00 37.25  ? 53  ARG E CB  1 
ATOM   9553  C  CG  . ARG E 1 53  ? 31.507  -8.103  38.833  1.00 41.32  ? 53  ARG E CG  1 
ATOM   9554  C  CD  . ARG E 1 53  ? 32.725  -9.050  38.442  1.00 44.63  ? 53  ARG E CD  1 
ATOM   9555  N  NE  . ARG E 1 53  ? 32.431  -10.473 38.660  1.00 44.94  ? 53  ARG E NE  1 
ATOM   9556  C  CZ  . ARG E 1 53  ? 31.985  -10.858 39.861  1.00 54.39  ? 53  ARG E CZ  1 
ATOM   9557  N  NH1 . ARG E 1 53  ? 31.884  -9.977  40.862  1.00 66.82  ? 53  ARG E NH1 1 
ATOM   9558  N  NH2 . ARG E 1 53  ? 31.603  -12.097 40.106  1.00 55.05  ? 53  ARG E NH2 1 
ATOM   9559  N  N   . ALA E 1 54  ? 28.723  -5.710  37.732  1.00 31.42  ? 54  ALA E N   1 
ATOM   9560  C  CA  . ALA E 1 54  ? 27.884  -5.707  36.531  1.00 34.60  ? 54  ALA E CA  1 
ATOM   9561  C  C   . ALA E 1 54  ? 27.007  -4.458  36.455  1.00 36.81  ? 54  ALA E C   1 
ATOM   9562  O  O   . ALA E 1 54  ? 26.052  -4.421  35.694  1.00 39.83  ? 54  ALA E O   1 
ATOM   9563  C  CB  . ALA E 1 54  ? 27.015  -6.947  36.448  1.00 32.29  ? 54  ALA E CB  1 
ATOM   9564  N  N   . GLN E 1 55  ? 27.369  -3.425  37.219  1.00 51.27  ? 55  GLN E N   1 
ATOM   9565  C  CA  . GLN E 1 55  ? 26.684  -2.140  37.123  1.00 63.95  ? 55  GLN E CA  1 
ATOM   9566  C  C   . GLN E 1 55  ? 26.986  -1.468  35.780  1.00 66.99  ? 55  GLN E C   1 
ATOM   9567  O  O   . GLN E 1 55  ? 27.982  -1.759  35.124  1.00 53.34  ? 55  GLN E O   1 
ATOM   9568  C  CB  . GLN E 1 55  ? 26.979  -1.203  38.303  1.00 68.48  ? 55  GLN E CB  1 
ATOM   9569  C  CG  . GLN E 1 55  ? 26.336  -1.657  39.620  1.00 68.15  ? 55  GLN E CG  1 
ATOM   9570  C  CD  . GLN E 1 55  ? 24.806  -1.743  39.637  1.00 86.64  ? 55  GLN E CD  1 
ATOM   9571  O  OE1 . GLN E 1 55  ? 24.132  -2.326  38.756  1.00 92.49  ? 55  GLN E OE1 1 
ATOM   9572  N  NE2 . GLN E 1 55  ? 24.215  -1.161  40.676  1.00 75.89  ? 55  GLN E NE2 1 
ATOM   9573  N  N   . PRO E 1 56  ? 26.072  -0.602  35.287  1.00 80.42  ? 56  PRO E N   1 
ATOM   9574  C  CA  . PRO E 1 56  ? 24.757  -0.380  35.924  1.00 71.70  ? 56  PRO E CA  1 
ATOM   9575  C  C   . PRO E 1 56  ? 23.586  -1.158  35.303  1.00 55.58  ? 56  PRO E C   1 
ATOM   9576  O  O   . PRO E 1 56  ? 22.498  -1.128  35.844  1.00 49.66  ? 56  PRO E O   1 
ATOM   9577  C  CB  . PRO E 1 56  ? 24.621  1.160   35.787  1.00 65.71  ? 56  PRO E CB  1 
ATOM   9578  C  CG  . PRO E 1 56  ? 25.501  1.525   34.563  1.00 68.25  ? 56  PRO E CG  1 
ATOM   9579  C  CD  . PRO E 1 56  ? 26.283  0.278   34.123  1.00 71.07  ? 56  PRO E CD  1 
ATOM   9580  N  N   . ASP E 1 57  ? 23.828  -1.882  34.202  1.00 49.48  ? 57  ASP E N   1 
ATOM   9581  C  CA  . ASP E 1 57  ? 22.808  -2.679  33.521  1.00 63.60  ? 57  ASP E CA  1 
ATOM   9582  C  C   . ASP E 1 57  ? 22.281  -3.885  34.326  1.00 54.17  ? 57  ASP E C   1 
ATOM   9583  O  O   . ASP E 1 57  ? 21.248  -4.434  33.952  1.00 41.45  ? 57  ASP E O   1 
ATOM   9584  C  CB  . ASP E 1 57  ? 23.351  -3.539  32.386  1.00 70.58  ? 57  ASP E CB  1 
ATOM   9585  C  CG  . ASP E 1 57  ? 24.474  -2.988  31.535  1.00 75.93  ? 57  ASP E CG  1 
ATOM   9586  O  OD1 . ASP E 1 57  ? 24.133  -2.135  30.702  1.00 72.88  ? 57  ASP E OD1 1 
ATOM   9587  O  OD2 . ASP E 1 57  ? 25.645  -3.435  31.725  1.00 77.05  ? 57  ASP E OD2 1 
ATOM   9588  N  N   . GLY E 1 58  ? 23.042  -4.389  35.315  1.00 40.35  ? 58  GLY E N   1 
ATOM   9589  C  CA  . GLY E 1 58  ? 22.705  -5.668  35.919  1.00 41.40  ? 58  GLY E CA  1 
ATOM   9590  C  C   . GLY E 1 58  ? 21.393  -5.676  36.731  1.00 32.92  ? 58  GLY E C   1 
ATOM   9591  O  O   . GLY E 1 58  ? 20.591  -6.603  36.601  1.00 33.58  ? 58  GLY E O   1 
ATOM   9592  N  N   . ARG E 1 59  ? 21.243  -4.692  37.628  1.00 32.45  ? 59  ARG E N   1 
ATOM   9593  C  CA  . ARG E 1 59  ? 20.002  -4.499  38.363  1.00 36.23  ? 59  ARG E CA  1 
ATOM   9594  C  C   . ARG E 1 59  ? 19.714  -5.716  39.231  1.00 31.06  ? 59  ARG E C   1 
ATOM   9595  O  O   . ARG E 1 59  ? 18.573  -6.068  39.448  1.00 31.79  ? 59  ARG E O   1 
ATOM   9596  C  CB  . ARG E 1 59  ? 18.807  -4.255  37.418  1.00 46.39  ? 59  ARG E CB  1 
ATOM   9597  C  CG  . ARG E 1 59  ? 18.867  -2.920  36.696  1.00 56.58  ? 59  ARG E CG  1 
ATOM   9598  C  CD  . ARG E 1 59  ? 17.592  -2.719  35.943  1.00 68.31  ? 59  ARG E CD  1 
ATOM   9599  N  NE  . ARG E 1 59  ? 18.013  -1.801  34.883  1.00 89.72  ? 59  ARG E NE  1 
ATOM   9600  C  CZ  . ARG E 1 59  ? 18.608  -2.144  33.733  1.00 92.48  ? 59  ARG E CZ  1 
ATOM   9601  N  NH1 . ARG E 1 59  ? 18.567  -3.377  33.249  1.00 79.70  ? 59  ARG E NH1 1 
ATOM   9602  N  NH2 . ARG E 1 59  ? 19.191  -1.199  33.030  1.00 93.30  ? 59  ARG E NH2 1 
ATOM   9603  N  N   . LEU E 1 60  ? 20.750  -6.381  39.709  1.00 26.28  ? 60  LEU E N   1 
ATOM   9604  C  CA  . LEU E 1 60  ? 20.575  -7.573  40.520  1.00 26.63  ? 60  LEU E CA  1 
ATOM   9605  C  C   . LEU E 1 60  ? 20.104  -7.198  41.909  1.00 30.48  ? 60  LEU E C   1 
ATOM   9606  O  O   . LEU E 1 60  ? 20.763  -6.394  42.510  1.00 32.22  ? 60  LEU E O   1 
ATOM   9607  C  CB  . LEU E 1 60  ? 21.891  -8.305  40.630  1.00 27.42  ? 60  LEU E CB  1 
ATOM   9608  C  CG  . LEU E 1 60  ? 21.882  -9.549  41.527  1.00 33.79  ? 60  LEU E CG  1 
ATOM   9609  C  CD1 . LEU E 1 60  ? 21.103  -10.707 40.959  1.00 31.36  ? 60  LEU E CD1 1 
ATOM   9610  C  CD2 . LEU E 1 60  ? 23.333  -9.989  41.817  1.00 39.95  ? 60  LEU E CD2 1 
ATOM   9611  N  N   . SER E 1 61  ? 19.055  -7.849  42.429  1.00 28.24  ? 61  SER E N   1 
ATOM   9612  C  CA  . SER E 1 61  ? 18.641  -7.723  43.800  1.00 26.54  ? 61  SER E CA  1 
ATOM   9613  C  C   . SER E 1 61  ? 18.146  -9.071  44.300  1.00 25.51  ? 61  SER E C   1 
ATOM   9614  O  O   . SER E 1 61  ? 17.801  -9.931  43.534  1.00 27.93  ? 61  SER E O   1 
ATOM   9615  C  CB  . SER E 1 61  ? 17.585  -6.643  43.979  1.00 25.94  ? 61  SER E CB  1 
ATOM   9616  O  OG  . SER E 1 61  ? 16.414  -6.932  43.253  1.00 29.66  ? 61  SER E OG  1 
ATOM   9617  N  N   . CYS E 1 62  ? 18.049  -9.202  45.615  1.00 26.98  ? 62  CYS E N   1 
ATOM   9618  C  CA  . CYS E 1 62  ? 17.584  -10.411 46.278  1.00 27.92  ? 62  CYS E CA  1 
ATOM   9619  C  C   . CYS E 1 62  ? 16.675  -9.961  47.404  1.00 25.36  ? 62  CYS E C   1 
ATOM   9620  O  O   . CYS E 1 62  ? 17.083  -9.141  48.225  1.00 23.42  ? 62  CYS E O   1 
ATOM   9621  C  CB  . CYS E 1 62  ? 18.723  -11.248 46.877  1.00 27.49  ? 62  CYS E CB  1 
ATOM   9622  S  SG  . CYS E 1 62  ? 18.127  -12.751 47.692  1.00 28.53  ? 62  CYS E SG  1 
ATOM   9623  N  N   . VAL E 1 63  ? 15.409  -10.387 47.406  1.00 24.75  ? 63  VAL E N   1 
ATOM   9624  C  CA  . VAL E 1 63  ? 14.556  -10.156 48.580  1.00 26.02  ? 63  VAL E CA  1 
ATOM   9625  C  C   . VAL E 1 63  ? 14.405  -11.471 49.352  1.00 22.84  ? 63  VAL E C   1 
ATOM   9626  O  O   . VAL E 1 63  ? 14.131  -12.502 48.754  1.00 23.58  ? 63  VAL E O   1 
ATOM   9627  C  CB  . VAL E 1 63  ? 13.205  -9.593  48.176  1.00 24.46  ? 63  VAL E CB  1 
ATOM   9628  C  CG1 . VAL E 1 63  ? 12.312  -9.446  49.378  1.00 26.66  ? 63  VAL E CG1 1 
ATOM   9629  C  CG2 . VAL E 1 63  ? 13.404  -8.227  47.570  1.00 25.98  ? 63  VAL E CG2 1 
ATOM   9630  N  N   . THR E 1 64  ? 14.733  -11.449 50.630  1.00 21.21  ? 64  THR E N   1 
ATOM   9631  C  CA  . THR E 1 64  ? 14.715  -12.655 51.445  1.00 23.79  ? 64  THR E CA  1 
ATOM   9632  C  C   . THR E 1 64  ? 13.498  -12.563 52.376  1.00 25.37  ? 64  THR E C   1 
ATOM   9633  O  O   . THR E 1 64  ? 13.286  -11.568 53.080  1.00 26.71  ? 64  THR E O   1 
ATOM   9634  C  CB  . THR E 1 64  ? 15.952  -12.708 52.317  1.00 26.29  ? 64  THR E CB  1 
ATOM   9635  O  OG1 . THR E 1 64  ? 17.079  -12.677 51.468  1.00 26.88  ? 64  THR E OG1 1 
ATOM   9636  C  CG2 . THR E 1 64  ? 15.998  -13.933 53.191  1.00 24.84  ? 64  THR E CG2 1 
ATOM   9637  N  N   . GLY E 1 65  ? 12.727  -13.629 52.400  1.00 24.08  ? 65  GLY E N   1 
ATOM   9638  C  CA  . GLY E 1 65  ? 11.590  -13.751 53.261  1.00 23.59  ? 65  GLY E CA  1 
ATOM   9639  C  C   . GLY E 1 65  ? 11.619  -15.011 54.139  1.00 23.20  ? 65  GLY E C   1 
ATOM   9640  O  O   . GLY E 1 65  ? 12.205  -16.054 53.841  1.00 22.12  ? 65  GLY E O   1 
ATOM   9641  N  N   . ILE E 1 66  ? 10.974  -14.859 55.283  1.00 27.16  ? 66  ILE E N   1 
ATOM   9642  C  CA  . ILE E 1 66  ? 10.955  -15.877 56.319  1.00 28.85  ? 66  ILE E CA  1 
ATOM   9643  C  C   . ILE E 1 66  ? 9.486   -16.218 56.644  1.00 29.87  ? 66  ILE E C   1 
ATOM   9644  O  O   . ILE E 1 66  ? 8.655   -15.320 56.823  1.00 22.77  ? 66  ILE E O   1 
ATOM   9645  C  CB  . ILE E 1 66  ? 11.733  -15.314 57.523  1.00 29.86  ? 66  ILE E CB  1 
ATOM   9646  C  CG1 . ILE E 1 66  ? 13.147  -14.939 57.103  1.00 30.66  ? 66  ILE E CG1 1 
ATOM   9647  C  CG2 . ILE E 1 66  ? 11.765  -16.347 58.656  1.00 31.75  ? 66  ILE E CG2 1 
ATOM   9648  C  CD1 . ILE E 1 66  ? 13.571  -13.696 57.811  1.00 35.44  ? 66  ILE E CD1 1 
ATOM   9649  N  N   . GLY E 1 67  ? 9.168   -17.520 56.692  1.00 26.92  ? 67  GLY E N   1 
ATOM   9650  C  CA  . GLY E 1 67  ? 7.840   -17.983 57.034  1.00 26.30  ? 67  GLY E CA  1 
ATOM   9651  C  C   . GLY E 1 67  ? 7.559   -17.942 58.539  1.00 24.54  ? 67  GLY E C   1 
ATOM   9652  O  O   . GLY E 1 67  ? 8.442   -17.716 59.364  1.00 22.02  ? 67  GLY E O   1 
ATOM   9653  N  N   . SER E 1 68  ? 6.285   -18.165 58.858  1.00 26.67  ? 68  SER E N   1 
ATOM   9654  C  CA  . SER E 1 68  ? 5.756   -18.111 60.229  1.00 29.18  ? 68  SER E CA  1 
ATOM   9655  C  C   . SER E 1 68  ? 6.436   -19.105 61.195  1.00 22.26  ? 68  SER E C   1 
ATOM   9656  O  O   . SER E 1 68  ? 6.966   -18.722 62.215  1.00 23.47  ? 68  SER E O   1 
ATOM   9657  C  CB  . SER E 1 68  ? 4.249   -18.349 60.163  1.00 31.27  ? 68  SER E CB  1 
ATOM   9658  O  OG  . SER E 1 68  ? 3.635   -17.969 61.371  1.00 27.33  ? 68  SER E OG  1 
ATOM   9659  N  N   . GLU E 1 69  ? 6.470   -20.384 60.869  1.00 22.54  ? 69  GLU E N   1 
ATOM   9660  C  CA  . GLU E 1 69  ? 7.134   -21.358 61.708  1.00 26.47  ? 69  GLU E CA  1 
ATOM   9661  C  C   . GLU E 1 69  ? 8.637   -21.126 61.808  1.00 29.57  ? 69  GLU E C   1 
ATOM   9662  O  O   . GLU E 1 69  ? 9.239   -21.295 62.880  1.00 26.07  ? 69  GLU E O   1 
ATOM   9663  C  CB  . GLU E 1 69  ? 6.914   -22.782 61.222  1.00 30.14  ? 69  GLU E CB  1 
ATOM   9664  C  CG  . GLU E 1 69  ? 5.454   -23.212 61.392  1.00 34.92  ? 69  GLU E CG  1 
ATOM   9665  C  CD  . GLU E 1 69  ? 5.095   -23.495 62.842  1.00 37.15  ? 69  GLU E CD  1 
ATOM   9666  O  OE1 . GLU E 1 69  ? 5.761   -24.339 63.466  1.00 36.52  ? 69  GLU E OE1 1 
ATOM   9667  O  OE2 . GLU E 1 69  ? 4.207   -22.831 63.344  1.00 34.41  ? 69  GLU E OE2 1 
ATOM   9668  N  N   . ALA E 1 70  ? 9.250   -20.781 60.680  1.00 25.13  ? 70  ALA E N   1 
ATOM   9669  C  CA  . ALA E 1 70  ? 10.672  -20.541 60.689  1.00 25.75  ? 70  ALA E CA  1 
ATOM   9670  C  C   . ALA E 1 70  ? 11.011  -19.354 61.592  1.00 25.81  ? 70  ALA E C   1 
ATOM   9671  O  O   . ALA E 1 70  ? 12.065  -19.342 62.262  1.00 26.15  ? 70  ALA E O   1 
ATOM   9672  C  CB  . ALA E 1 70  ? 11.150  -20.311 59.283  1.00 30.27  ? 70  ALA E CB  1 
ATOM   9673  N  N   . TRP E 1 71  ? 10.146  -18.334 61.576  1.00 24.01  ? 71  TRP E N   1 
ATOM   9674  C  CA  . TRP E 1 71  ? 10.403  -17.163 62.386  1.00 27.23  ? 71  TRP E CA  1 
ATOM   9675  C  C   . TRP E 1 71  ? 10.691  -17.525 63.857  1.00 30.55  ? 71  TRP E C   1 
ATOM   9676  O  O   . TRP E 1 71  ? 11.600  -17.008 64.490  1.00 29.13  ? 71  TRP E O   1 
ATOM   9677  C  CB  . TRP E 1 71  ? 9.231   -16.185 62.275  1.00 27.78  ? 71  TRP E CB  1 
ATOM   9678  C  CG  . TRP E 1 71  ? 9.595   -14.889 62.924  1.00 28.07  ? 71  TRP E CG  1 
ATOM   9679  C  CD1 . TRP E 1 71  ? 9.620   -14.614 64.259  1.00 28.79  ? 71  TRP E CD1 1 
ATOM   9680  C  CD2 . TRP E 1 71  ? 10.157  -13.739 62.254  1.00 30.49  ? 71  TRP E CD2 1 
ATOM   9681  N  NE1 . TRP E 1 71  ? 10.074  -13.327 64.456  1.00 29.78  ? 71  TRP E NE1 1 
ATOM   9682  C  CE2 . TRP E 1 71  ? 10.434  -12.783 63.263  1.00 30.15  ? 71  TRP E CE2 1 
ATOM   9683  C  CE3 . TRP E 1 71  ? 10.429  -13.426 60.921  1.00 27.73  ? 71  TRP E CE3 1 
ATOM   9684  C  CZ2 . TRP E 1 71  ? 10.969  -11.550 62.973  1.00 30.48  ? 71  TRP E CZ2 1 
ATOM   9685  C  CZ3 . TRP E 1 71  ? 10.963  -12.189 60.641  1.00 26.52  ? 71  TRP E CZ3 1 
ATOM   9686  C  CH2 . TRP E 1 71  ? 11.256  -11.291 61.650  1.00 27.08  ? 71  TRP E CH2 1 
ATOM   9687  N  N   . ASP E 1 72  ? 9.873   -18.422 64.402  1.00 32.70  ? 72  ASP E N   1 
ATOM   9688  C  CA  . ASP E 1 72  ? 9.918   -18.807 65.804  1.00 30.80  ? 72  ASP E CA  1 
ATOM   9689  C  C   . ASP E 1 72  ? 11.115  -19.694 66.058  1.00 29.02  ? 72  ASP E C   1 
ATOM   9690  O  O   . ASP E 1 72  ? 11.670  -19.573 67.121  1.00 27.87  ? 72  ASP E O   1 
ATOM   9691  C  CB  . ASP E 1 72  ? 8.661   -19.539 66.234  1.00 39.26  ? 72  ASP E CB  1 
ATOM   9692  C  CG  . ASP E 1 72  ? 7.413   -18.672 66.236  1.00 37.97  ? 72  ASP E CG  1 
ATOM   9693  O  OD1 . ASP E 1 72  ? 7.579   -17.474 66.351  1.00 34.70  ? 72  ASP E OD1 1 
ATOM   9694  O  OD2 . ASP E 1 72  ? 6.310   -19.194 66.010  1.00 49.36  ? 72  ASP E OD2 1 
ATOM   9695  N  N   . ARG E 1 73  ? 11.612  -20.456 65.073  1.00 30.93  ? 73  ARG E N   1 
ATOM   9696  C  CA  . ARG E 1 73  ? 12.863  -21.185 65.251  1.00 24.64  ? 73  ARG E CA  1 
ATOM   9697  C  C   . ARG E 1 73  ? 14.069  -20.266 65.236  1.00 27.06  ? 73  ARG E C   1 
ATOM   9698  O  O   . ARG E 1 73  ? 15.118  -20.656 65.699  1.00 24.96  ? 73  ARG E O   1 
ATOM   9699  C  CB  . ARG E 1 73  ? 13.074  -22.233 64.147  1.00 26.77  ? 73  ARG E CB  1 
ATOM   9700  C  CG  . ARG E 1 73  ? 12.039  -23.345 64.214  1.00 23.42  ? 73  ARG E CG  1 
ATOM   9701  C  CD  . ARG E 1 73  ? 11.961  -24.118 62.974  1.00 25.81  ? 73  ARG E CD  1 
ATOM   9702  N  NE  . ARG E 1 73  ? 13.212  -24.836 62.765  1.00 25.75  ? 73  ARG E NE  1 
ATOM   9703  C  CZ  . ARG E 1 73  ? 13.492  -25.561 61.691  1.00 26.22  ? 73  ARG E CZ  1 
ATOM   9704  N  NH1 . ARG E 1 73  ? 12.619  -25.625 60.701  1.00 27.08  ? 73  ARG E NH1 1 
ATOM   9705  N  NH2 . ARG E 1 73  ? 14.637  -26.217 61.614  1.00 28.63  ? 73  ARG E NH2 1 
ATOM   9706  N  N   . LEU E 1 74  ? 13.971  -19.090 64.588  1.00 33.14  ? 74  LEU E N   1 
ATOM   9707  C  CA  . LEU E 1 74  ? 15.174  -18.365 64.217  1.00 30.92  ? 74  LEU E CA  1 
ATOM   9708  C  C   . LEU E 1 74  ? 15.417  -17.265 65.211  1.00 28.63  ? 74  LEU E C   1 
ATOM   9709  O  O   . LEU E 1 74  ? 16.559  -16.913 65.419  1.00 36.01  ? 74  LEU E O   1 
ATOM   9710  C  CB  . LEU E 1 74  ? 15.113  -17.822 62.794  1.00 28.14  ? 74  LEU E CB  1 
ATOM   9711  C  CG  . LEU E 1 74  ? 15.334  -18.846 61.670  1.00 29.32  ? 74  LEU E CG  1 
ATOM   9712  C  CD1 . LEU E 1 74  ? 15.001  -18.284 60.284  1.00 38.25  ? 74  LEU E CD1 1 
ATOM   9713  C  CD2 . LEU E 1 74  ? 16.758  -19.317 61.734  1.00 26.51  ? 74  LEU E CD2 1 
ATOM   9714  N  N   . PHE E 1 75  ? 14.343  -16.655 65.675  1.00 29.80  ? 75  PHE E N   1 
ATOM   9715  C  CA  . PHE E 1 75  ? 14.378  -15.405 66.413  1.00 32.20  ? 75  PHE E CA  1 
ATOM   9716  C  C   . PHE E 1 75  ? 13.519  -15.532 67.670  1.00 41.53  ? 75  PHE E C   1 
ATOM   9717  O  O   . PHE E 1 75  ? 12.471  -16.174 67.696  1.00 45.04  ? 75  PHE E O   1 
ATOM   9718  C  CB  . PHE E 1 75  ? 13.750  -14.293 65.566  1.00 30.16  ? 75  PHE E CB  1 
ATOM   9719  C  CG  . PHE E 1 75  ? 14.351  -14.189 64.178  1.00 31.84  ? 75  PHE E CG  1 
ATOM   9720  C  CD1 . PHE E 1 75  ? 15.704  -14.006 64.010  1.00 32.41  ? 75  PHE E CD1 1 
ATOM   9721  C  CD2 . PHE E 1 75  ? 13.577  -14.344 63.050  1.00 34.96  ? 75  PHE E CD2 1 
ATOM   9722  C  CE1 . PHE E 1 75  ? 16.270  -13.966 62.731  1.00 36.49  ? 75  PHE E CE1 1 
ATOM   9723  C  CE2 . PHE E 1 75  ? 14.146  -14.331 61.775  1.00 36.30  ? 75  PHE E CE2 1 
ATOM   9724  C  CZ  . PHE E 1 75  ? 15.492  -14.158 61.619  1.00 34.82  ? 75  PHE E CZ  1 
ATOM   9725  N  N   . SER E 1 76  ? 13.865  -14.826 68.732  1.00 55.25  ? 76  SER E N   1 
ATOM   9726  C  CA  . SER E 1 76  ? 12.810  -14.612 69.703  1.00 57.25  ? 76  SER E CA  1 
ATOM   9727  C  C   . SER E 1 76  ? 12.685  -13.122 69.948  1.00 43.34  ? 76  SER E C   1 
ATOM   9728  O  O   . SER E 1 76  ? 13.402  -12.283 69.424  1.00 45.31  ? 76  SER E O   1 
ATOM   9729  C  CB  . SER E 1 76  ? 12.968  -15.413 70.955  1.00 67.13  ? 76  SER E CB  1 
ATOM   9730  O  OG  . SER E 1 76  ? 14.192  -15.032 71.553  1.00 68.21  ? 76  SER E OG  1 
ATOM   9731  N  N   . GLY E 1 77  ? 11.642  -12.821 70.664  1.00 42.95  ? 77  GLY E N   1 
ATOM   9732  C  CA  . GLY E 1 77  ? 11.161  -11.471 70.710  1.00 47.37  ? 77  GLY E CA  1 
ATOM   9733  C  C   . GLY E 1 77  ? 9.971   -11.383 69.781  1.00 47.20  ? 77  GLY E C   1 
ATOM   9734  O  O   . GLY E 1 77  ? 9.396   -12.368 69.334  1.00 53.11  ? 77  GLY E O   1 
ATOM   9735  N  N   . ALA E 1 78  ? 9.654   -10.161 69.412  1.00 46.70  ? 78  ALA E N   1 
ATOM   9736  C  CA  . ALA E 1 78  ? 8.387   -9.900  68.784  1.00 47.38  ? 78  ALA E CA  1 
ATOM   9737  C  C   . ALA E 1 78  ? 8.342   -10.681 67.476  1.00 35.65  ? 78  ALA E C   1 
ATOM   9738  O  O   . ALA E 1 78  ? 9.364   -10.951 66.869  1.00 37.14  ? 78  ALA E O   1 
ATOM   9739  C  CB  . ALA E 1 78  ? 8.262   -8.387  68.639  1.00 53.86  ? 78  ALA E CB  1 
ATOM   9740  N  N   . ARG E 1 79  ? 7.132   -11.048 67.080  1.00 40.25  ? 79  ARG E N   1 
ATOM   9741  C  CA  . ARG E 1 79  ? 6.789   -11.500 65.743  1.00 39.10  ? 79  ARG E CA  1 
ATOM   9742  C  C   . ARG E 1 79  ? 6.151   -10.334 65.002  1.00 37.37  ? 79  ARG E C   1 
ATOM   9743  O  O   . ARG E 1 79  ? 5.426   -9.541  65.570  1.00 33.72  ? 79  ARG E O   1 
ATOM   9744  C  CB  . ARG E 1 79  ? 5.721   -12.598 65.785  1.00 36.25  ? 79  ARG E CB  1 
ATOM   9745  C  CG  . ARG E 1 79  ? 6.274   -13.854 66.441  1.00 37.05  ? 79  ARG E CG  1 
ATOM   9746  C  CD  . ARG E 1 79  ? 5.276   -14.958 66.485  1.00 33.69  ? 79  ARG E CD  1 
ATOM   9747  N  NE  . ARG E 1 79  ? 4.534   -15.014 65.223  1.00 36.75  ? 79  ARG E NE  1 
ATOM   9748  C  CZ  . ARG E 1 79  ? 4.753   -15.906 64.268  1.00 36.56  ? 79  ARG E CZ  1 
ATOM   9749  N  NH1 . ARG E 1 79  ? 5.762   -16.744 64.373  1.00 37.54  ? 79  ARG E NH1 1 
ATOM   9750  N  NH2 . ARG E 1 79  ? 3.992   -15.914 63.192  1.00 42.54  ? 79  ARG E NH2 1 
ATOM   9751  N  N   . PRO E 1 80  ? 6.355   -10.204 63.677  1.00 48.44  ? 80  PRO E N   1 
ATOM   9752  C  CA  . PRO E 1 80  ? 5.563   -9.238  62.922  1.00 43.09  ? 80  PRO E CA  1 
ATOM   9753  C  C   . PRO E 1 80  ? 4.078   -9.570  63.126  1.00 34.13  ? 80  PRO E C   1 
ATOM   9754  O  O   . PRO E 1 80  ? 3.700   -10.741 63.074  1.00 28.29  ? 80  PRO E O   1 
ATOM   9755  C  CB  . PRO E 1 80  ? 6.032   -9.547  61.470  1.00 42.36  ? 80  PRO E CB  1 
ATOM   9756  C  CG  . PRO E 1 80  ? 7.383   -10.203 61.619  1.00 46.42  ? 80  PRO E CG  1 
ATOM   9757  C  CD  . PRO E 1 80  ? 7.302   -11.012 62.864  1.00 45.44  ? 80  PRO E CD  1 
ATOM   9758  N  N   . ALA E 1 81  ? 3.257   -8.520  63.249  1.00 38.81  ? 81  ALA E N   1 
ATOM   9759  C  CA  . ALA E 1 81  ? 1.809   -8.606  63.491  1.00 36.19  ? 81  ALA E CA  1 
ATOM   9760  C  C   . ALA E 1 81  ? 1.057   -9.540  62.535  1.00 37.43  ? 81  ALA E C   1 
ATOM   9761  O  O   . ALA E 1 81  ? 0.188   -10.262 62.975  1.00 31.86  ? 81  ALA E O   1 
ATOM   9762  C  CB  . ALA E 1 81  ? 1.199   -7.219  63.420  1.00 31.55  ? 81  ALA E CB  1 
ATOM   9763  N  N   . GLY E 1 82  ? 1.363   -9.534  61.222  1.00 34.57  ? 82  GLY E N   1 
ATOM   9764  C  CA  . GLY E 1 82  ? 0.565   -10.240 60.234  1.00 28.97  ? 82  GLY E CA  1 
ATOM   9765  C  C   . GLY E 1 82  ? 1.074   -11.627 59.899  1.00 30.99  ? 82  GLY E C   1 
ATOM   9766  O  O   . GLY E 1 82  ? 0.502   -12.287 59.025  1.00 34.43  ? 82  GLY E O   1 
ATOM   9767  N  N   . LEU E 1 83  ? 2.138   -12.110 60.562  1.00 29.34  ? 83  LEU E N   1 
ATOM   9768  C  CA  . LEU E 1 83  ? 2.779   -13.319 60.046  1.00 29.32  ? 83  LEU E CA  1 
ATOM   9769  C  C   . LEU E 1 83  ? 2.020   -14.560 60.497  1.00 25.69  ? 83  LEU E C   1 
ATOM   9770  O  O   . LEU E 1 83  ? 1.868   -14.770 61.660  1.00 25.95  ? 83  LEU E O   1 
ATOM   9771  C  CB  . LEU E 1 83  ? 4.243   -13.340 60.472  1.00 31.57  ? 83  LEU E CB  1 
ATOM   9772  C  CG  . LEU E 1 83  ? 5.079   -14.492 59.890  1.00 34.11  ? 83  LEU E CG  1 
ATOM   9773  C  CD1 . LEU E 1 83  ? 5.052   -14.603 58.377  1.00 34.31  ? 83  LEU E CD1 1 
ATOM   9774  C  CD2 . LEU E 1 83  ? 6.510   -14.376 60.385  1.00 35.22  ? 83  LEU E CD2 1 
ATOM   9775  N  N   . HIS E 1 84  ? 1.592   -15.407 59.577  1.00 26.28  ? 84  HIS E N   1 
ATOM   9776  C  CA  . HIS E 1 84  ? 0.938   -16.670 59.866  1.00 23.82  ? 84  HIS E CA  1 
ATOM   9777  C  C   . HIS E 1 84  ? 1.161   -17.562 58.634  1.00 26.39  ? 84  HIS E C   1 
ATOM   9778  O  O   . HIS E 1 84  ? 1.574   -17.102 57.547  1.00 25.02  ? 84  HIS E O   1 
ATOM   9779  C  CB  . HIS E 1 84  ? -0.573  -16.501 60.148  1.00 22.50  ? 84  HIS E CB  1 
ATOM   9780  C  CG  . HIS E 1 84  ? -1.297  -15.670 59.145  1.00 23.34  ? 84  HIS E CG  1 
ATOM   9781  N  ND1 . HIS E 1 84  ? -1.537  -14.318 59.379  1.00 26.62  ? 84  HIS E ND1 1 
ATOM   9782  C  CD2 . HIS E 1 84  ? -1.723  -15.918 57.872  1.00 21.22  ? 84  HIS E CD2 1 
ATOM   9783  C  CE1 . HIS E 1 84  ? -2.175  -13.777 58.325  1.00 26.68  ? 84  HIS E CE1 1 
ATOM   9784  N  NE2 . HIS E 1 84  ? -2.252  -14.728 57.377  1.00 24.08  ? 84  HIS E NE2 1 
ATOM   9785  N  N   . PRO E 1 85  ? 0.858   -18.882 58.753  1.00 26.18  ? 85  PRO E N   1 
ATOM   9786  C  CA  . PRO E 1 85  ? 0.897   -19.790 57.624  1.00 26.13  ? 85  PRO E CA  1 
ATOM   9787  C  C   . PRO E 1 85  ? -0.158  -19.384 56.622  1.00 27.41  ? 85  PRO E C   1 
ATOM   9788  O  O   . PRO E 1 85  ? -1.212  -18.894 57.002  1.00 24.45  ? 85  PRO E O   1 
ATOM   9789  C  CB  . PRO E 1 85  ? 0.583   -21.153 58.205  1.00 26.85  ? 85  PRO E CB  1 
ATOM   9790  C  CG  . PRO E 1 85  ? 0.984   -20.962 59.662  1.00 28.32  ? 85  PRO E CG  1 
ATOM   9791  C  CD  . PRO E 1 85  ? 0.512   -19.566 60.003  1.00 25.79  ? 85  PRO E CD  1 
ATOM   9792  N  N   . PHE E 1 86  ? 0.206   -19.608 55.363  1.00 31.48  ? 86  PHE E N   1 
ATOM   9793  C  CA  . PHE E 1 86  ? -0.691  -19.406 54.233  1.00 33.47  ? 86  PHE E CA  1 
ATOM   9794  C  C   . PHE E 1 86  ? -1.961  -20.214 54.499  1.00 34.86  ? 86  PHE E C   1 
ATOM   9795  O  O   . PHE E 1 86  ? -1.846  -21.385 54.894  1.00 34.43  ? 86  PHE E O   1 
ATOM   9796  C  CB  . PHE E 1 86  ? 0.016   -19.818 52.927  1.00 27.85  ? 86  PHE E CB  1 
ATOM   9797  C  CG  . PHE E 1 86  ? -0.770  -19.600 51.649  1.00 26.28  ? 86  PHE E CG  1 
ATOM   9798  C  CD1 . PHE E 1 86  ? -1.650  -20.579 51.189  1.00 26.46  ? 86  PHE E CD1 1 
ATOM   9799  C  CD2 . PHE E 1 86  ? -0.566  -18.472 50.870  1.00 27.98  ? 86  PHE E CD2 1 
ATOM   9800  C  CE1 . PHE E 1 86  ? -2.342  -20.432 49.983  1.00 26.71  ? 86  PHE E CE1 1 
ATOM   9801  C  CE2 . PHE E 1 86  ? -1.241  -18.330 49.660  1.00 31.16  ? 86  PHE E CE2 1 
ATOM   9802  C  CZ  . PHE E 1 86  ? -2.168  -19.288 49.246  1.00 27.93  ? 86  PHE E CZ  1 
ATOM   9803  N  N   . ARG E 1 87  ? -3.124  -19.595 54.239  1.00 30.13  ? 87  ARG E N   1 
ATOM   9804  C  CA  . ARG E 1 87  ? -4.402  -20.244 54.451  1.00 34.49  ? 87  ARG E CA  1 
ATOM   9805  C  C   . ARG E 1 87  ? -4.964  -20.803 53.157  1.00 31.07  ? 87  ARG E C   1 
ATOM   9806  O  O   . ARG E 1 87  ? -5.363  -20.015 52.297  1.00 31.03  ? 87  ARG E O   1 
ATOM   9807  C  CB  . ARG E 1 87  ? -5.465  -19.240 54.848  1.00 46.71  ? 87  ARG E CB  1 
ATOM   9808  C  CG  . ARG E 1 87  ? -5.153  -18.597 56.172  1.00 61.85  ? 87  ARG E CG  1 
ATOM   9809  C  CD  . ARG E 1 87  ? -5.776  -17.212 56.172  1.00 82.32  ? 87  ARG E CD  1 
ATOM   9810  N  NE  . ARG E 1 87  ? -4.899  -16.867 57.287  1.00 100.98 ? 87  ARG E NE  1 
ATOM   9811  C  CZ  . ARG E 1 87  ? -5.297  -16.322 58.404  1.00 87.27  ? 87  ARG E CZ  1 
ATOM   9812  N  NH1 . ARG E 1 87  ? -6.036  -15.232 58.334  1.00 78.17  ? 87  ARG E NH1 1 
ATOM   9813  N  NH2 . ARG E 1 87  ? -4.779  -16.766 59.542  1.00 73.74  ? 87  ARG E NH2 1 
ATOM   9814  N  N   . GLU E 1 88  ? -5.029  -22.149 53.104  1.00 33.28  ? 88  GLU E N   1 
ATOM   9815  C  CA  . GLU E 1 88  ? -5.707  -22.921 52.085  1.00 32.96  ? 88  GLU E CA  1 
ATOM   9816  C  C   . GLU E 1 88  ? -7.095  -22.336 51.892  1.00 34.63  ? 88  GLU E C   1 
ATOM   9817  O  O   . GLU E 1 88  ? -7.694  -21.949 52.865  1.00 30.19  ? 88  GLU E O   1 
ATOM   9818  C  CB  . GLU E 1 88  ? -6.100  -24.355 52.421  1.00 37.57  ? 88  GLU E CB  1 
ATOM   9819  C  CG  . GLU E 1 88  ? -5.011  -25.089 53.162  1.00 59.95  ? 88  GLU E CG  1 
ATOM   9820  C  CD  . GLU E 1 88  ? -4.655  -26.417 52.543  1.00 72.68  ? 88  GLU E CD  1 
ATOM   9821  O  OE1 . GLU E 1 88  ? -4.934  -26.769 51.357  1.00 70.80  ? 88  GLU E OE1 1 
ATOM   9822  O  OE2 . GLU E 1 88  ? -3.980  -27.058 53.365  1.00 81.51  ? 88  GLU E OE2 1 
ATOM   9823  N  N   . LEU E 1 89  ? -7.554  -22.202 50.636  1.00 35.17  ? 89  LEU E N   1 
ATOM   9824  C  CA  . LEU E 1 89  ? -8.916  -21.822 50.315  1.00 31.93  ? 89  LEU E CA  1 
ATOM   9825  C  C   . LEU E 1 89  ? -9.482  -22.947 49.455  1.00 38.33  ? 89  LEU E C   1 
ATOM   9826  O  O   . LEU E 1 89  ? -8.947  -23.278 48.382  1.00 38.59  ? 89  LEU E O   1 
ATOM   9827  C  CB  . LEU E 1 89  ? -8.980  -20.495 49.586  1.00 30.37  ? 89  LEU E CB  1 
ATOM   9828  C  CG  . LEU E 1 89  ? -8.385  -19.275 50.279  1.00 32.71  ? 89  LEU E CG  1 
ATOM   9829  C  CD1 . LEU E 1 89  ? -8.500  -18.056 49.378  1.00 36.16  ? 89  LEU E CD1 1 
ATOM   9830  C  CD2 . LEU E 1 89  ? -9.017  -18.951 51.554  1.00 31.92  ? 89  LEU E CD2 1 
ATOM   9831  N  N   . ASP E 1 90  ? -10.548 -23.562 49.997  1.00 51.92  ? 90  ASP E N   1 
ATOM   9832  C  CA  . ASP E 1 90  ? -11.261 -24.695 49.412  1.00 52.03  ? 90  ASP E CA  1 
ATOM   9833  C  C   . ASP E 1 90  ? -12.547 -24.185 48.777  1.00 36.33  ? 90  ASP E C   1 
ATOM   9834  O  O   . ASP E 1 90  ? -13.550 -23.999 49.426  1.00 37.48  ? 90  ASP E O   1 
ATOM   9835  C  CB  . ASP E 1 90  ? -11.574 -25.735 50.458  1.00 56.94  ? 90  ASP E CB  1 
ATOM   9836  C  CG  . ASP E 1 90  ? -11.067 -27.058 49.976  1.00 70.65  ? 90  ASP E CG  1 
ATOM   9837  O  OD1 . ASP E 1 90  ? -11.473 -27.424 48.839  1.00 65.28  ? 90  ASP E OD1 1 
ATOM   9838  O  OD2 . ASP E 1 90  ? -10.185 -27.563 50.680  1.00 76.66  ? 90  ASP E OD2 1 
ATOM   9839  N  N   . GLY E 1 91  ? -12.436 -23.763 47.537  1.00 33.36  ? 91  GLY E N   1 
ATOM   9840  C  CA  . GLY E 1 91  ? -13.561 -23.178 46.871  1.00 41.94  ? 91  GLY E CA  1 
ATOM   9841  C  C   . GLY E 1 91  ? -14.445 -24.259 46.274  1.00 40.24  ? 91  GLY E C   1 
ATOM   9842  O  O   . GLY E 1 91  ? -14.064 -25.452 46.164  1.00 43.53  ? 91  GLY E O   1 
ATOM   9843  N  N   . PRO E 1 92  ? -15.662 -23.843 45.862  1.00 38.38  ? 92  PRO E N   1 
ATOM   9844  C  CA  . PRO E 1 92  ? -16.583 -24.810 45.253  1.00 39.18  ? 92  PRO E CA  1 
ATOM   9845  C  C   . PRO E 1 92  ? -15.925 -25.556 44.091  1.00 41.88  ? 92  PRO E C   1 
ATOM   9846  O  O   . PRO E 1 92  ? -16.117 -26.736 43.926  1.00 38.21  ? 92  PRO E O   1 
ATOM   9847  C  CB  . PRO E 1 92  ? -17.797 -23.941 44.805  1.00 39.78  ? 92  PRO E CB  1 
ATOM   9848  C  CG  . PRO E 1 92  ? -17.504 -22.454 45.243  1.00 38.76  ? 92  PRO E CG  1 
ATOM   9849  C  CD  . PRO E 1 92  ? -16.201 -22.466 46.022  1.00 37.52  ? 92  PRO E CD  1 
ATOM   9850  N  N   . VAL E 1 93  ? -15.131 -24.860 43.263  1.00 42.77  ? 93  VAL E N   1 
ATOM   9851  C  CA  . VAL E 1 93  ? -14.517 -25.455 42.094  1.00 36.13  ? 93  VAL E CA  1 
ATOM   9852  C  C   . VAL E 1 93  ? -13.000 -25.442 42.213  1.00 33.29  ? 93  VAL E C   1 
ATOM   9853  O  O   . VAL E 1 93  ? -12.332 -26.409 41.888  1.00 35.35  ? 93  VAL E O   1 
ATOM   9854  C  CB  . VAL E 1 93  ? -14.968 -24.660 40.844  1.00 40.80  ? 93  VAL E CB  1 
ATOM   9855  C  CG1 . VAL E 1 93  ? -14.249 -25.131 39.573  1.00 44.98  ? 93  VAL E CG1 1 
ATOM   9856  C  CG2 . VAL E 1 93  ? -16.449 -24.757 40.607  1.00 33.50  ? 93  VAL E CG2 1 
ATOM   9857  N  N   . HIS E 1 94  ? -12.433 -24.301 42.618  1.00 32.21  ? 94  HIS E N   1 
ATOM   9858  C  CA  . HIS E 1 94  ? -10.985 -24.111 42.585  1.00 32.29  ? 94  HIS E CA  1 
ATOM   9859  C  C   . HIS E 1 94  ? -10.405 -24.089 44.007  1.00 29.50  ? 94  HIS E C   1 
ATOM   9860  O  O   . HIS E 1 94  ? -10.996 -23.469 44.887  1.00 40.10  ? 94  HIS E O   1 
ATOM   9861  C  CB  . HIS E 1 94  ? -10.713 -22.810 41.792  1.00 32.16  ? 94  HIS E CB  1 
ATOM   9862  C  CG  . HIS E 1 94  ? -11.062 -22.880 40.356  1.00 27.75  ? 94  HIS E CG  1 
ATOM   9863  N  ND1 . HIS E 1 94  ? -10.510 -23.765 39.435  1.00 28.59  ? 94  HIS E ND1 1 
ATOM   9864  C  CD2 . HIS E 1 94  ? -11.989 -22.162 39.701  1.00 28.11  ? 94  HIS E CD2 1 
ATOM   9865  C  CE1 . HIS E 1 94  ? -11.078 -23.563 38.249  1.00 31.91  ? 94  HIS E CE1 1 
ATOM   9866  N  NE2 . HIS E 1 94  ? -11.992 -22.592 38.383  1.00 32.23  ? 94  HIS E NE2 1 
ATOM   9867  N  N   . ARG E 1 95  ? -9.181  -24.574 44.183  1.00 30.39  ? 95  ARG E N   1 
ATOM   9868  C  CA  . ARG E 1 95  ? -8.509  -24.622 45.484  1.00 33.12  ? 95  ARG E CA  1 
ATOM   9869  C  C   . ARG E 1 95  ? -7.182  -23.866 45.422  1.00 26.29  ? 95  ARG E C   1 
ATOM   9870  O  O   . ARG E 1 95  ? -6.416  -24.058 44.498  1.00 26.79  ? 95  ARG E O   1 
ATOM   9871  C  CB  . ARG E 1 95  ? -8.372  -26.135 45.627  1.00 34.23  ? 95  ARG E CB  1 
ATOM   9872  C  CG  . ARG E 1 95  ? -7.698  -26.769 46.818  1.00 46.43  ? 95  ARG E CG  1 
ATOM   9873  C  CD  . ARG E 1 95  ? -8.066  -28.296 46.638  1.00 56.61  ? 95  ARG E CD  1 
ATOM   9874  N  NE  . ARG E 1 95  ? -7.923  -28.786 48.007  1.00 71.05  ? 95  ARG E NE  1 
ATOM   9875  C  CZ  . ARG E 1 95  ? -6.736  -28.897 48.617  1.00 79.88  ? 95  ARG E CZ  1 
ATOM   9876  N  NH1 . ARG E 1 95  ? -5.727  -29.433 47.941  1.00 67.67  ? 95  ARG E NH1 1 
ATOM   9877  N  NH2 . ARG E 1 95  ? -6.607  -28.615 49.919  1.00 74.45  ? 95  ARG E NH2 1 
ATOM   9878  N  N   . ALA E 1 96  ? -6.924  -23.015 46.408  1.00 29.00  ? 96  ALA E N   1 
ATOM   9879  C  CA  . ALA E 1 96  ? -5.598  -22.446 46.680  1.00 25.05  ? 96  ALA E CA  1 
ATOM   9880  C  C   . ALA E 1 96  ? -4.856  -23.302 47.707  1.00 26.60  ? 96  ALA E C   1 
ATOM   9881  O  O   . ALA E 1 96  ? -5.171  -23.253 48.880  1.00 28.89  ? 96  ALA E O   1 
ATOM   9882  C  CB  . ALA E 1 96  ? -5.745  -21.002 47.153  1.00 23.60  ? 96  ALA E CB  1 
ATOM   9883  N  N   . VAL E 1 97  ? -3.875  -24.104 47.266  1.00 25.45  ? 97  VAL E N   1 
ATOM   9884  C  CA  . VAL E 1 97  ? -3.173  -25.018 48.154  1.00 27.51  ? 97  VAL E CA  1 
ATOM   9885  C  C   . VAL E 1 97  ? -2.105  -24.339 48.977  1.00 25.25  ? 97  VAL E C   1 
ATOM   9886  O  O   . VAL E 1 97  ? -1.665  -23.241 48.695  1.00 26.79  ? 97  VAL E O   1 
ATOM   9887  C  CB  . VAL E 1 97  ? -2.527  -26.158 47.390  1.00 32.69  ? 97  VAL E CB  1 
ATOM   9888  C  CG1 . VAL E 1 97  ? -3.540  -26.923 46.568  1.00 34.54  ? 97  VAL E CG1 1 
ATOM   9889  C  CG2 . VAL E 1 97  ? -1.480  -25.650 46.452  1.00 35.77  ? 97  VAL E CG2 1 
ATOM   9890  N  N   . ALA E 1 98  ? -1.709  -25.028 50.042  1.00 28.22  ? 98  ALA E N   1 
ATOM   9891  C  CA  . ALA E 1 98  ? -0.632  -24.554 50.914  1.00 27.91  ? 98  ALA E CA  1 
ATOM   9892  C  C   . ALA E 1 98  ? 0.451   -25.575 50.767  1.00 27.49  ? 98  ALA E C   1 
ATOM   9893  O  O   . ALA E 1 98  ? 0.165   -26.774 50.750  1.00 30.54  ? 98  ALA E O   1 
ATOM   9894  C  CB  . ALA E 1 98  ? -1.026  -24.375 52.364  1.00 24.59  ? 98  ALA E CB  1 
ATOM   9895  N  N   . THR E 1 99  ? 1.662   -25.101 50.577  1.00 28.27  ? 99  THR E N   1 
ATOM   9896  C  CA  . THR E 1 99  ? 2.808   -26.003 50.534  1.00 31.68  ? 99  THR E CA  1 
ATOM   9897  C  C   . THR E 1 99  ? 3.882   -25.437 51.469  1.00 27.95  ? 99  THR E C   1 
ATOM   9898  O  O   . THR E 1 99  ? 3.902   -24.256 51.772  1.00 21.56  ? 99  THR E O   1 
ATOM   9899  C  CB  . THR E 1 99  ? 3.346   -26.199 49.100  1.00 33.40  ? 99  THR E CB  1 
ATOM   9900  O  OG1 . THR E 1 99  ? 3.543   -24.919 48.495  1.00 25.22  ? 99  THR E OG1 1 
ATOM   9901  C  CG2 . THR E 1 99  ? 2.362   -26.983 48.249  1.00 36.47  ? 99  THR E CG2 1 
ATOM   9902  N  N   . PRO E 1 100 ? 4.831   -26.284 51.919  1.00 23.38  ? 100 PRO E N   1 
ATOM   9903  C  CA  . PRO E 1 100 ? 5.860   -25.875 52.864  1.00 22.83  ? 100 PRO E CA  1 
ATOM   9904  C  C   . PRO E 1 100 ? 6.904   -24.925 52.273  1.00 24.64  ? 100 PRO E C   1 
ATOM   9905  O  O   . PRO E 1 100 ? 7.242   -25.002 51.095  1.00 23.43  ? 100 PRO E O   1 
ATOM   9906  C  CB  . PRO E 1 100 ? 6.512   -27.151 53.260  1.00 25.10  ? 100 PRO E CB  1 
ATOM   9907  C  CG  . PRO E 1 100 ? 5.748   -28.263 52.541  1.00 22.26  ? 100 PRO E CG  1 
ATOM   9908  C  CD  . PRO E 1 100 ? 4.929   -27.678 51.481  1.00 22.06  ? 100 PRO E CD  1 
ATOM   9909  N  N   . GLY E 1 101 ? 7.375   -24.034 53.136  1.00 21.20  ? 101 GLY E N   1 
ATOM   9910  C  CA  . GLY E 1 101 ? 8.328   -23.026 52.815  1.00 19.28  ? 101 GLY E CA  1 
ATOM   9911  C  C   . GLY E 1 101 ? 8.748   -22.253 54.051  1.00 21.38  ? 101 GLY E C   1 
ATOM   9912  O  O   . GLY E 1 101 ? 7.954   -21.530 54.627  1.00 23.98  ? 101 GLY E O   1 
ATOM   9913  N  N   . ASP E 1 102 ? 10.032  -22.313 54.392  1.00 21.98  ? 102 ASP E N   1 
ATOM   9914  C  CA  . ASP E 1 102 ? 10.545  -21.550 55.506  1.00 21.45  ? 102 ASP E CA  1 
ATOM   9915  C  C   . ASP E 1 102 ? 11.250  -20.280 55.037  1.00 22.15  ? 102 ASP E C   1 
ATOM   9916  O  O   . ASP E 1 102 ? 11.195  -19.287 55.726  1.00 21.91  ? 102 ASP E O   1 
ATOM   9917  C  CB  . ASP E 1 102 ? 11.471  -22.423 56.335  1.00 23.49  ? 102 ASP E CB  1 
ATOM   9918  C  CG  . ASP E 1 102 ? 10.786  -23.559 57.062  1.00 26.22  ? 102 ASP E CG  1 
ATOM   9919  O  OD1 . ASP E 1 102 ? 9.597   -23.356 57.437  1.00 25.60  ? 102 ASP E OD1 1 
ATOM   9920  O  OD2 . ASP E 1 102 ? 11.453  -24.595 57.270  1.00 22.37  ? 102 ASP E OD2 1 
ATOM   9921  N  N   . LEU E 1 103 ? 11.963  -20.334 53.907  1.00 25.61  ? 103 LEU E N   1 
ATOM   9922  C  CA  . LEU E 1 103 ? 12.758  -19.206 53.405  1.00 25.97  ? 103 LEU E CA  1 
ATOM   9923  C  C   . LEU E 1 103 ? 12.434  -19.011 51.938  1.00 23.54  ? 103 LEU E C   1 
ATOM   9924  O  O   . LEU E 1 103 ? 12.332  -19.998 51.228  1.00 27.56  ? 103 LEU E O   1 
ATOM   9925  C  CB  . LEU E 1 103 ? 14.248  -19.511 53.527  1.00 25.70  ? 103 LEU E CB  1 
ATOM   9926  C  CG  . LEU E 1 103 ? 14.814  -19.621 54.955  1.00 25.79  ? 103 LEU E CG  1 
ATOM   9927  C  CD1 . LEU E 1 103 ? 16.277  -19.960 54.938  1.00 24.42  ? 103 LEU E CD1 1 
ATOM   9928  C  CD2 . LEU E 1 103 ? 14.623  -18.287 55.673  1.00 29.02  ? 103 LEU E CD2 1 
ATOM   9929  N  N   . LEU E 1 104 ? 12.288  -17.758 51.520  1.00 19.72  ? 104 LEU E N   1 
ATOM   9930  C  CA  . LEU E 1 104 ? 12.113  -17.347 50.139  1.00 21.83  ? 104 LEU E CA  1 
ATOM   9931  C  C   . LEU E 1 104 ? 13.338  -16.515 49.716  1.00 22.99  ? 104 LEU E C   1 
ATOM   9932  O  O   . LEU E 1 104 ? 13.704  -15.590 50.432  1.00 22.58  ? 104 LEU E O   1 
ATOM   9933  C  CB  . LEU E 1 104 ? 10.867  -16.454 50.034  1.00 22.61  ? 104 LEU E CB  1 
ATOM   9934  C  CG  . LEU E 1 104 ? 10.646  -15.665 48.727  1.00 23.47  ? 104 LEU E CG  1 
ATOM   9935  C  CD1 . LEU E 1 104 ? 10.332  -16.586 47.560  1.00 24.66  ? 104 LEU E CD1 1 
ATOM   9936  C  CD2 . LEU E 1 104 ? 9.556   -14.618 48.794  1.00 22.04  ? 104 LEU E CD2 1 
ATOM   9937  N  N   . PHE E 1 105 ? 13.908  -16.811 48.548  1.00 19.35  ? 105 PHE E N   1 
ATOM   9938  C  CA  . PHE E 1 105 ? 14.853  -15.907 47.892  1.00 20.80  ? 105 PHE E CA  1 
ATOM   9939  C  C   . PHE E 1 105 ? 14.238  -15.514 46.556  1.00 18.34  ? 105 PHE E C   1 
ATOM   9940  O  O   . PHE E 1 105 ? 13.998  -16.349 45.704  1.00 21.97  ? 105 PHE E O   1 
ATOM   9941  C  CB  . PHE E 1 105 ? 16.269  -16.486 47.763  1.00 21.32  ? 105 PHE E CB  1 
ATOM   9942  C  CG  . PHE E 1 105 ? 16.841  -16.946 49.079  1.00 19.56  ? 105 PHE E CG  1 
ATOM   9943  C  CD1 . PHE E 1 105 ? 17.402  -16.049 49.944  1.00 20.86  ? 105 PHE E CD1 1 
ATOM   9944  C  CD2 . PHE E 1 105 ? 16.775  -18.243 49.462  1.00 21.20  ? 105 PHE E CD2 1 
ATOM   9945  C  CE1 . PHE E 1 105 ? 17.855  -16.432 51.182  1.00 23.68  ? 105 PHE E CE1 1 
ATOM   9946  C  CE2 . PHE E 1 105 ? 17.221  -18.619 50.705  1.00 24.69  ? 105 PHE E CE2 1 
ATOM   9947  C  CZ  . PHE E 1 105 ? 17.783  -17.711 51.565  1.00 22.18  ? 105 PHE E CZ  1 
ATOM   9948  N  N   . HIS E 1 106 ? 13.914  -14.255 46.403  1.00 18.01  ? 106 HIS E N   1 
ATOM   9949  C  CA  . HIS E 1 106 ? 13.328  -13.715 45.187  1.00 18.55  ? 106 HIS E CA  1 
ATOM   9950  C  C   . HIS E 1 106 ? 14.429  -12.846 44.580  1.00 20.01  ? 106 HIS E C   1 
ATOM   9951  O  O   . HIS E 1 106 ? 14.719  -11.744 45.053  1.00 18.51  ? 106 HIS E O   1 
ATOM   9952  C  CB  . HIS E 1 106 ? 12.106  -12.838 45.503  1.00 19.61  ? 106 HIS E CB  1 
ATOM   9953  C  CG  . HIS E 1 106 ? 11.465  -12.179 44.350  1.00 20.84  ? 106 HIS E CG  1 
ATOM   9954  N  ND1 . HIS E 1 106 ? 10.718  -11.020 44.464  1.00 23.19  ? 106 HIS E ND1 1 
ATOM   9955  C  CD2 . HIS E 1 106 ? 11.501  -12.481 43.084  1.00 21.41  ? 106 HIS E CD2 1 
ATOM   9956  C  CE1 . HIS E 1 106 ? 10.250  -10.711 43.275  1.00 24.31  ? 106 HIS E CE1 1 
ATOM   9957  N  NE2 . HIS E 1 106 ? 10.740  -11.570 42.409  1.00 22.49  ? 106 HIS E NE2 1 
ATOM   9958  N  N   . ILE E 1 107 ? 15.073  -13.429 43.581  1.00 20.90  ? 107 ILE E N   1 
ATOM   9959  C  CA  . ILE E 1 107 ? 16.271  -12.887 42.985  1.00 21.06  ? 107 ILE E CA  1 
ATOM   9960  C  C   . ILE E 1 107 ? 15.901  -12.367 41.613  1.00 19.65  ? 107 ILE E C   1 
ATOM   9961  O  O   . ILE E 1 107 ? 15.317  -13.089 40.822  1.00 19.17  ? 107 ILE E O   1 
ATOM   9962  C  CB  . ILE E 1 107 ? 17.344  -13.973 42.935  1.00 22.82  ? 107 ILE E CB  1 
ATOM   9963  C  CG1 . ILE E 1 107 ? 17.647  -14.553 44.295  1.00 24.47  ? 107 ILE E CG1 1 
ATOM   9964  C  CG2 . ILE E 1 107 ? 18.575  -13.380 42.287  1.00 27.17  ? 107 ILE E CG2 1 
ATOM   9965  C  CD1 . ILE E 1 107 ? 18.642  -15.701 44.291  1.00 27.56  ? 107 ILE E CD1 1 
ATOM   9966  N  N   . ARG E 1 108 ? 16.205  -11.108 41.363  1.00 21.69  ? 108 ARG E N   1 
ATOM   9967  C  CA  . ARG E 1 108 ? 15.842  -10.469 40.095  1.00 26.23  ? 108 ARG E CA  1 
ATOM   9968  C  C   . ARG E 1 108 ? 17.057  -9.797  39.449  1.00 26.50  ? 108 ARG E C   1 
ATOM   9969  O  O   . ARG E 1 108 ? 17.913  -9.275  40.146  1.00 24.51  ? 108 ARG E O   1 
ATOM   9970  C  CB  . ARG E 1 108 ? 14.749  -9.415  40.277  1.00 25.52  ? 108 ARG E CB  1 
ATOM   9971  C  CG  . ARG E 1 108 ? 13.404  -10.074 40.576  1.00 28.35  ? 108 ARG E CG  1 
ATOM   9972  C  CD  . ARG E 1 108 ? 12.336  -9.026  40.861  1.00 28.21  ? 108 ARG E CD  1 
ATOM   9973  N  NE  . ARG E 1 108 ? 12.529  -8.353  42.146  1.00 32.38  ? 108 ARG E NE  1 
ATOM   9974  C  CZ  . ARG E 1 108 ? 11.663  -7.583  42.761  1.00 31.74  ? 108 ARG E CZ  1 
ATOM   9975  N  NH1 . ARG E 1 108 ? 10.533  -7.337  42.151  1.00 37.32  ? 108 ARG E NH1 1 
ATOM   9976  N  NH2 . ARG E 1 108 ? 11.901  -7.115  43.975  1.00 30.89  ? 108 ARG E NH2 1 
ATOM   9977  N  N   . ALA E 1 109 ? 17.082  -9.774  38.113  1.00 22.88  ? 109 ALA E N   1 
ATOM   9978  C  CA  . ALA E 1 109 ? 18.095  -9.011  37.446  1.00 24.11  ? 109 ALA E CA  1 
ATOM   9979  C  C   . ALA E 1 109 ? 17.715  -8.837  35.988  1.00 24.74  ? 109 ALA E C   1 
ATOM   9980  O  O   . ALA E 1 109 ? 16.746  -9.420  35.525  1.00 23.45  ? 109 ALA E O   1 
ATOM   9981  C  CB  . ALA E 1 109 ? 19.392  -9.759  37.542  1.00 26.40  ? 109 ALA E CB  1 
ATOM   9982  N  N   . SER E 1 110 ? 18.552  -8.105  35.249  1.00 27.49  ? 110 SER E N   1 
ATOM   9983  C  CA  . SER E 1 110 ? 18.338  -8.001  33.806  1.00 30.51  ? 110 SER E CA  1 
ATOM   9984  C  C   . SER E 1 110 ? 18.826  -9.247  33.069  1.00 28.02  ? 110 SER E C   1 
ATOM   9985  O  O   . SER E 1 110 ? 18.421  -9.418  31.947  1.00 33.20  ? 110 SER E O   1 
ATOM   9986  C  CB  . SER E 1 110 ? 18.950  -6.775  33.229  1.00 32.55  ? 110 SER E CB  1 
ATOM   9987  O  OG  . SER E 1 110 ? 20.363  -6.843  33.408  1.00 36.52  ? 110 SER E OG  1 
ATOM   9988  N  N   . ARG E 1 111 ? 19.586  -10.172 33.658  1.00 24.98  ? 111 ARG E N   1 
ATOM   9989  C  CA  . ARG E 1 111 ? 19.903  -11.386 32.900  1.00 27.19  ? 111 ARG E CA  1 
ATOM   9990  C  C   . ARG E 1 111 ? 19.958  -12.579 33.858  1.00 24.64  ? 111 ARG E C   1 
ATOM   9991  O  O   . ARG E 1 111 ? 20.301  -12.445 35.030  1.00 23.30  ? 111 ARG E O   1 
ATOM   9992  C  CB  . ARG E 1 111 ? 21.344  -11.317 32.367  1.00 32.87  ? 111 ARG E CB  1 
ATOM   9993  C  CG  . ARG E 1 111 ? 22.016  -9.967  32.144  1.00 35.99  ? 111 ARG E CG  1 
ATOM   9994  C  CD  . ARG E 1 111 ? 23.573  -9.891  31.923  1.00 35.71  ? 111 ARG E CD  1 
ATOM   9995  N  NE  . ARG E 1 111 ? 24.242  -11.049 31.309  1.00 36.52  ? 111 ARG E NE  1 
ATOM   9996  C  CZ  . ARG E 1 111 ? 24.543  -11.373 30.052  1.00 36.42  ? 111 ARG E CZ  1 
ATOM   9997  N  NH1 . ARG E 1 111 ? 24.479  -10.492 29.084  1.00 42.80  ? 111 ARG E NH1 1 
ATOM   9998  N  NH2 . ARG E 1 111 ? 24.917  -12.595 29.725  1.00 38.88  ? 111 ARG E NH2 1 
ATOM   9999  N  N   . LEU E 1 112 ? 19.616  -13.765 33.365  1.00 24.73  ? 112 LEU E N   1 
ATOM   10000 C  CA  . LEU E 1 112 ? 19.476  -14.919 34.231  1.00 25.63  ? 112 LEU E CA  1 
ATOM   10001 C  C   . LEU E 1 112 ? 20.776  -15.306 34.944  1.00 34.79  ? 112 LEU E C   1 
ATOM   10002 O  O   . LEU E 1 112 ? 20.770  -15.760 36.107  1.00 27.36  ? 112 LEU E O   1 
ATOM   10003 C  CB  . LEU E 1 112 ? 19.005  -16.062 33.368  1.00 30.97  ? 112 LEU E CB  1 
ATOM   10004 C  CG  . LEU E 1 112 ? 18.539  -17.292 34.151  1.00 36.53  ? 112 LEU E CG  1 
ATOM   10005 C  CD1 . LEU E 1 112 ? 17.561  -16.888 35.249  1.00 32.73  ? 112 LEU E CD1 1 
ATOM   10006 C  CD2 . LEU E 1 112 ? 17.856  -18.249 33.169  1.00 39.97  ? 112 LEU E CD2 1 
ATOM   10007 N  N   . ASP E 1 113 ? 21.907  -15.112 34.244  1.00 33.10  ? 113 ASP E N   1 
ATOM   10008 C  CA  . ASP E 1 113 ? 23.200  -15.534 34.740  1.00 27.40  ? 113 ASP E CA  1 
ATOM   10009 C  C   . ASP E 1 113 ? 23.498  -14.842 36.054  1.00 23.18  ? 113 ASP E C   1 
ATOM   10010 O  O   . ASP E 1 113 ? 24.139  -15.469 36.895  1.00 26.81  ? 113 ASP E O   1 
ATOM   10011 C  CB  . ASP E 1 113 ? 24.337  -15.357 33.737  1.00 28.68  ? 113 ASP E CB  1 
ATOM   10012 C  CG  . ASP E 1 113 ? 24.463  -13.939 33.220  1.00 28.83  ? 113 ASP E CG  1 
ATOM   10013 O  OD1 . ASP E 1 113 ? 23.528  -13.656 32.366  1.00 30.65  ? 113 ASP E OD1 1 
ATOM   10014 O  OD2 . ASP E 1 113 ? 25.387  -13.155 33.722  1.00 31.69  ? 113 ASP E OD2 1 
ATOM   10015 N  N   . LEU E 1 114 ? 23.117  -13.586 36.218  1.00 21.72  ? 114 LEU E N   1 
ATOM   10016 C  CA  . LEU E 1 114 ? 23.386  -12.902 37.469  1.00 24.23  ? 114 LEU E CA  1 
ATOM   10017 C  C   . LEU E 1 114 ? 22.576  -13.491 38.615  1.00 26.93  ? 114 LEU E C   1 
ATOM   10018 O  O   . LEU E 1 114 ? 23.093  -13.624 39.728  1.00 25.49  ? 114 LEU E O   1 
ATOM   10019 C  CB  . LEU E 1 114 ? 23.040  -11.434 37.338  1.00 27.19  ? 114 LEU E CB  1 
ATOM   10020 C  CG  . LEU E 1 114 ? 24.026  -10.638 36.470  1.00 31.36  ? 114 LEU E CG  1 
ATOM   10021 C  CD1 . LEU E 1 114 ? 23.455  -9.233  36.287  1.00 28.34  ? 114 LEU E CD1 1 
ATOM   10022 C  CD2 . LEU E 1 114 ? 25.428  -10.581 37.120  1.00 30.89  ? 114 LEU E CD2 1 
ATOM   10023 N  N   . CYS E 1 115 ? 21.307  -13.799 38.315  1.00 23.88  ? 115 CYS E N   1 
ATOM   10024 C  CA  . CYS E 1 115 ? 20.426  -14.431 39.269  1.00 21.55  ? 115 CYS E CA  1 
ATOM   10025 C  C   . CYS E 1 115 ? 21.052  -15.743 39.704  1.00 22.38  ? 115 CYS E C   1 
ATOM   10026 O  O   . CYS E 1 115 ? 21.062  -16.046 40.889  1.00 21.33  ? 115 CYS E O   1 
ATOM   10027 C  CB  . CYS E 1 115 ? 19.059  -14.690 38.650  1.00 20.36  ? 115 CYS E CB  1 
ATOM   10028 S  SG  . CYS E 1 115 ? 18.205  -13.150 38.234  1.00 23.67  ? 115 CYS E SG  1 
ATOM   10029 N  N   . PHE E 1 116 ? 21.515  -16.533 38.720  1.00 21.79  ? 116 PHE E N   1 
ATOM   10030 C  CA  . PHE E 1 116 ? 22.068  -17.855 38.987  1.00 20.41  ? 116 PHE E CA  1 
ATOM   10031 C  C   . PHE E 1 116 ? 23.333  -17.780 39.824  1.00 21.33  ? 116 PHE E C   1 
ATOM   10032 O  O   . PHE E 1 116 ? 23.567  -18.560 40.722  1.00 21.35  ? 116 PHE E O   1 
ATOM   10033 C  CB  . PHE E 1 116 ? 22.233  -18.582 37.655  1.00 20.20  ? 116 PHE E CB  1 
ATOM   10034 C  CG  . PHE E 1 116 ? 22.544  -20.046 37.826  1.00 21.12  ? 116 PHE E CG  1 
ATOM   10035 C  CD1 . PHE E 1 116 ? 21.527  -20.950 37.988  1.00 25.70  ? 116 PHE E CD1 1 
ATOM   10036 C  CD2 . PHE E 1 116 ? 23.832  -20.517 37.968  1.00 25.27  ? 116 PHE E CD2 1 
ATOM   10037 C  CE1 . PHE E 1 116 ? 21.775  -22.274 38.295  1.00 27.10  ? 116 PHE E CE1 1 
ATOM   10038 C  CE2 . PHE E 1 116 ? 24.075  -21.848 38.208  1.00 23.95  ? 116 PHE E CE2 1 
ATOM   10039 C  CZ  . PHE E 1 116 ? 23.053  -22.737 38.354  1.00 25.89  ? 116 PHE E CZ  1 
ATOM   10040 N  N   . ALA E 1 117 ? 24.128  -16.774 39.572  1.00 22.06  ? 117 ALA E N   1 
ATOM   10041 C  CA  . ALA E 1 117 ? 25.377  -16.603 40.284  1.00 23.04  ? 117 ALA E CA  1 
ATOM   10042 C  C   . ALA E 1 117 ? 25.101  -16.319 41.745  1.00 21.83  ? 117 ALA E C   1 
ATOM   10043 O  O   . ALA E 1 117 ? 25.759  -16.878 42.605  1.00 22.12  ? 117 ALA E O   1 
ATOM   10044 C  CB  . ALA E 1 117 ? 26.206  -15.528 39.653  1.00 20.02  ? 117 ALA E CB  1 
ATOM   10045 N  N   . LEU E 1 118 ? 24.162  -15.426 42.020  1.00 23.11  ? 118 LEU E N   1 
ATOM   10046 C  CA  . LEU E 1 118 ? 23.815  -15.155 43.423  1.00 23.70  ? 118 LEU E CA  1 
ATOM   10047 C  C   . LEU E 1 118 ? 23.131  -16.375 44.100  1.00 25.35  ? 118 LEU E C   1 
ATOM   10048 O  O   . LEU E 1 118 ? 23.443  -16.701 45.264  1.00 24.18  ? 118 LEU E O   1 
ATOM   10049 C  CB  . LEU E 1 118 ? 22.969  -13.904 43.511  1.00 22.12  ? 118 LEU E CB  1 
ATOM   10050 C  CG  . LEU E 1 118 ? 22.456  -13.537 44.896  1.00 25.99  ? 118 LEU E CG  1 
ATOM   10051 C  CD1 . LEU E 1 118 ? 23.616  -13.262 45.801  1.00 33.09  ? 118 LEU E CD1 1 
ATOM   10052 C  CD2 . LEU E 1 118 ? 21.587  -12.293 44.864  1.00 27.19  ? 118 LEU E CD2 1 
ATOM   10053 N  N   . ALA E 1 119 ? 22.220  -17.072 43.374  1.00 23.86  ? 119 ALA E N   1 
ATOM   10054 C  CA  . ALA E 1 119 ? 21.575  -18.271 43.896  1.00 23.15  ? 119 ALA E CA  1 
ATOM   10055 C  C   . ALA E 1 119 ? 22.602  -19.339 44.257  1.00 22.62  ? 119 ALA E C   1 
ATOM   10056 O  O   . ALA E 1 119 ? 22.450  -20.062 45.217  1.00 23.73  ? 119 ALA E O   1 
ATOM   10057 C  CB  . ALA E 1 119 ? 20.578  -18.817 42.887  1.00 22.43  ? 119 ALA E CB  1 
ATOM   10058 N  N   . THR E 1 120 ? 23.657  -19.439 43.457  1.00 20.86  ? 120 THR E N   1 
ATOM   10059 C  CA  . THR E 1 120 ? 24.696  -20.410 43.678  1.00 21.21  ? 120 THR E CA  1 
ATOM   10060 C  C   . THR E 1 120 ? 25.401  -20.086 44.974  1.00 22.93  ? 120 THR E C   1 
ATOM   10061 O  O   . THR E 1 120 ? 25.660  -20.989 45.759  1.00 21.05  ? 120 THR E O   1 
ATOM   10062 C  CB  . THR E 1 120 ? 25.678  -20.361 42.504  1.00 20.92  ? 120 THR E CB  1 
ATOM   10063 O  OG1 . THR E 1 120 ? 24.946  -20.963 41.452  1.00 24.07  ? 120 THR E OG1 1 
ATOM   10064 C  CG2 . THR E 1 120 ? 26.925  -21.195 42.688  1.00 21.89  ? 120 THR E CG2 1 
ATOM   10065 N  N   . GLU E 1 121 ? 25.726  -18.809 45.176  1.00 22.34  ? 121 GLU E N   1 
ATOM   10066 C  CA  . GLU E 1 121 ? 26.433  -18.420 46.387  1.00 27.59  ? 121 GLU E CA  1 
ATOM   10067 C  C   . GLU E 1 121 ? 25.547  -18.682 47.626  1.00 25.88  ? 121 GLU E C   1 
ATOM   10068 O  O   . GLU E 1 121 ? 26.020  -19.190 48.633  1.00 24.35  ? 121 GLU E O   1 
ATOM   10069 C  CB  . GLU E 1 121 ? 26.886  -16.947 46.433  1.00 28.06  ? 121 GLU E CB  1 
ATOM   10070 C  CG  . GLU E 1 121 ? 28.027  -16.564 45.492  1.00 34.23  ? 121 GLU E CG  1 
ATOM   10071 C  CD  . GLU E 1 121 ? 29.403  -17.089 45.778  1.00 32.70  ? 121 GLU E CD  1 
ATOM   10072 O  OE1 . GLU E 1 121 ? 29.712  -17.211 46.942  1.00 32.09  ? 121 GLU E OE1 1 
ATOM   10073 O  OE2 . GLU E 1 121 ? 30.099  -17.455 44.867  1.00 37.22  ? 121 GLU E OE2 1 
ATOM   10074 N  N   . ILE E 1 122 ? 24.263  -18.288 47.583  1.00 25.26  ? 122 ILE E N   1 
ATOM   10075 C  CA  . ILE E 1 122 ? 23.368  -18.473 48.717  1.00 23.11  ? 122 ILE E CA  1 
ATOM   10076 C  C   . ILE E 1 122 ? 23.241  -19.969 49.037  1.00 21.60  ? 122 ILE E C   1 
ATOM   10077 O  O   . ILE E 1 122 ? 23.480  -20.385 50.163  1.00 27.09  ? 122 ILE E O   1 
ATOM   10078 C  CB  . ILE E 1 122 ? 22.030  -17.787 48.421  1.00 24.44  ? 122 ILE E CB  1 
ATOM   10079 C  CG1 . ILE E 1 122 ? 22.153  -16.245 48.435  1.00 22.58  ? 122 ILE E CG1 1 
ATOM   10080 C  CG2 . ILE E 1 122 ? 20.919  -18.251 49.373  1.00 28.72  ? 122 ILE E CG2 1 
ATOM   10081 C  CD1 . ILE E 1 122 ? 20.948  -15.529 47.851  1.00 20.90  ? 122 ILE E CD1 1 
ATOM   10082 N  N   . MET E 1 123 ? 22.958  -20.812 48.050  1.00 20.88  ? 123 MET E N   1 
ATOM   10083 C  CA  . MET E 1 123 ? 22.755  -22.218 48.327  1.00 23.43  ? 123 MET E CA  1 
ATOM   10084 C  C   . MET E 1 123 ? 24.048  -22.874 48.766  1.00 30.48  ? 123 MET E C   1 
ATOM   10085 O  O   . MET E 1 123 ? 23.997  -23.860 49.498  1.00 37.02  ? 123 MET E O   1 
ATOM   10086 C  CB  . MET E 1 123 ? 22.170  -22.974 47.137  1.00 25.76  ? 123 MET E CB  1 
ATOM   10087 C  CG  . MET E 1 123 ? 20.702  -22.648 46.998  1.00 39.46  ? 123 MET E CG  1 
ATOM   10088 S  SD  . MET E 1 123 ? 19.622  -23.282 48.328  1.00 39.60  ? 123 MET E SD  1 
ATOM   10089 C  CE  . MET E 1 123 ? 20.180  -24.988 48.368  1.00 30.21  ? 123 MET E CE  1 
ATOM   10090 N  N   . GLY E 1 124 ? 25.190  -22.343 48.278  1.00 35.52  ? 124 GLY E N   1 
ATOM   10091 C  CA  . GLY E 1 124 ? 26.513  -22.796 48.707  1.00 31.13  ? 124 GLY E CA  1 
ATOM   10092 C  C   . GLY E 1 124 ? 26.673  -22.715 50.220  1.00 27.67  ? 124 GLY E C   1 
ATOM   10093 O  O   . GLY E 1 124 ? 27.147  -23.641 50.826  1.00 33.07  ? 124 GLY E O   1 
ATOM   10094 N  N   . ARG E 1 125 ? 26.242  -21.613 50.817  1.00 26.69  ? 125 ARG E N   1 
ATOM   10095 C  CA  . ARG E 1 125 ? 26.343  -21.381 52.240  1.00 30.44  ? 125 ARG E CA  1 
ATOM   10096 C  C   . ARG E 1 125 ? 25.293  -22.218 52.984  1.00 28.73  ? 125 ARG E C   1 
ATOM   10097 O  O   . ARG E 1 125 ? 25.479  -22.521 54.121  1.00 30.15  ? 125 ARG E O   1 
ATOM   10098 C  CB  . ARG E 1 125 ? 26.091  -19.898 52.543  1.00 33.63  ? 125 ARG E CB  1 
ATOM   10099 C  CG  . ARG E 1 125 ? 26.965  -18.882 51.808  1.00 42.88  ? 125 ARG E CG  1 
ATOM   10100 C  CD  . ARG E 1 125 ? 28.403  -18.584 52.226  1.00 48.79  ? 125 ARG E CD  1 
ATOM   10101 N  NE  . ARG E 1 125 ? 28.299  -18.287 53.659  1.00 61.09  ? 125 ARG E NE  1 
ATOM   10102 C  CZ  . ARG E 1 125 ? 28.160  -17.048 54.174  1.00 64.27  ? 125 ARG E CZ  1 
ATOM   10103 N  NH1 . ARG E 1 125 ? 28.640  -16.033 53.445  1.00 60.91  ? 125 ARG E NH1 1 
ATOM   10104 N  NH2 . ARG E 1 125 ? 27.546  -16.877 55.375  1.00 49.77  ? 125 ARG E NH2 1 
ATOM   10105 N  N   . LEU E 1 126 ? 24.223  -22.654 52.356  1.00 28.09  ? 126 LEU E N   1 
ATOM   10106 C  CA  . LEU E 1 126 ? 23.150  -23.334 53.053  1.00 25.43  ? 126 LEU E CA  1 
ATOM   10107 C  C   . LEU E 1 126 ? 23.255  -24.841 52.895  1.00 27.20  ? 126 LEU E C   1 
ATOM   10108 O  O   . LEU E 1 126 ? 22.397  -25.489 53.462  1.00 28.21  ? 126 LEU E O   1 
ATOM   10109 C  CB  . LEU E 1 126 ? 21.789  -22.820 52.554  1.00 24.31  ? 126 LEU E CB  1 
ATOM   10110 C  CG  . LEU E 1 126 ? 21.442  -21.354 52.864  1.00 26.49  ? 126 LEU E CG  1 
ATOM   10111 C  CD1 . LEU E 1 126 ? 20.123  -20.921 52.263  1.00 30.34  ? 126 LEU E CD1 1 
ATOM   10112 C  CD2 . LEU E 1 126 ? 21.392  -21.049 54.331  1.00 29.64  ? 126 LEU E CD2 1 
ATOM   10113 N  N   . ARG E 1 127 ? 24.178  -25.389 52.068  1.00 32.35  ? 127 ARG E N   1 
ATOM   10114 C  CA  . ARG E 1 127 ? 24.193  -26.817 51.738  1.00 33.94  ? 127 ARG E CA  1 
ATOM   10115 C  C   . ARG E 1 127 ? 24.145  -27.596 53.048  1.00 33.43  ? 127 ARG E C   1 
ATOM   10116 O  O   . ARG E 1 127 ? 24.834  -27.267 54.005  1.00 31.34  ? 127 ARG E O   1 
ATOM   10117 C  CB  . ARG E 1 127 ? 25.474  -27.390 51.131  1.00 43.66  ? 127 ARG E CB  1 
ATOM   10118 C  CG  . ARG E 1 127 ? 25.875  -27.158 49.675  1.00 71.95  ? 127 ARG E CG  1 
ATOM   10119 C  CD  . ARG E 1 127 ? 25.143  -27.960 48.578  1.00 79.27  ? 127 ARG E CD  1 
ATOM   10120 N  NE  . ARG E 1 127 ? 24.970  -27.250 47.294  1.00 86.61  ? 127 ARG E NE  1 
ATOM   10121 C  CZ  . ARG E 1 127 ? 23.825  -26.666 46.836  1.00 85.35  ? 127 ARG E CZ  1 
ATOM   10122 N  NH1 . ARG E 1 127 ? 22.766  -26.600 47.625  1.00 103.57 ? 127 ARG E NH1 1 
ATOM   10123 N  NH2 . ARG E 1 127 ? 23.717  -26.129 45.616  1.00 68.48  ? 127 ARG E NH2 1 
ATOM   10124 N  N   . GLY E 1 128 ? 23.290  -28.616 53.160  1.00 37.09  ? 128 GLY E N   1 
ATOM   10125 C  CA  . GLY E 1 128 ? 23.283  -29.424 54.381  1.00 32.53  ? 128 GLY E CA  1 
ATOM   10126 C  C   . GLY E 1 128 ? 22.498  -28.776 55.512  1.00 32.97  ? 128 GLY E C   1 
ATOM   10127 O  O   . GLY E 1 128 ? 22.300  -29.404 56.520  1.00 35.75  ? 128 GLY E O   1 
ATOM   10128 N  N   . ALA E 1 129 ? 21.988  -27.551 55.373  1.00 28.67  ? 129 ALA E N   1 
ATOM   10129 C  CA  . ALA E 1 129 ? 21.084  -27.004 56.362  1.00 24.51  ? 129 ALA E CA  1 
ATOM   10130 C  C   . ALA E 1 129 ? 19.651  -26.939 55.852  1.00 25.89  ? 129 ALA E C   1 
ATOM   10131 O  O   . ALA E 1 129 ? 18.767  -26.686 56.663  1.00 21.22  ? 129 ALA E O   1 
ATOM   10132 C  CB  . ALA E 1 129 ? 21.512  -25.633 56.811  1.00 23.20  ? 129 ALA E CB  1 
ATOM   10133 N  N   . VAL E 1 130 ? 19.419  -26.991 54.543  1.00 25.95  ? 130 VAL E N   1 
ATOM   10134 C  CA  . VAL E 1 130 ? 18.076  -26.714 54.038  1.00 23.62  ? 130 VAL E CA  1 
ATOM   10135 C  C   . VAL E 1 130 ? 17.708  -27.782 53.012  1.00 23.89  ? 130 VAL E C   1 
ATOM   10136 O  O   . VAL E 1 130 ? 18.578  -28.496 52.577  1.00 21.82  ? 130 VAL E O   1 
ATOM   10137 C  CB  . VAL E 1 130 ? 17.904  -25.335 53.430  1.00 23.05  ? 130 VAL E CB  1 
ATOM   10138 C  CG1 . VAL E 1 130 ? 18.322  -24.236 54.404  1.00 22.14  ? 130 VAL E CG1 1 
ATOM   10139 C  CG2 . VAL E 1 130 ? 18.704  -25.289 52.148  1.00 24.96  ? 130 VAL E CG2 1 
ATOM   10140 N  N   . THR E 1 131 ? 16.411  -27.905 52.673  1.00 26.60  ? 131 THR E N   1 
ATOM   10141 C  CA  . THR E 1 131 ? 15.888  -28.830 51.658  1.00 23.54  ? 131 THR E CA  1 
ATOM   10142 C  C   . THR E 1 131 ? 15.123  -28.007 50.658  1.00 24.61  ? 131 THR E C   1 
ATOM   10143 O  O   . THR E 1 131 ? 14.273  -27.203 51.032  1.00 25.53  ? 131 THR E O   1 
ATOM   10144 C  CB  . THR E 1 131 ? 15.016  -29.928 52.259  1.00 24.95  ? 131 THR E CB  1 
ATOM   10145 O  OG1 . THR E 1 131 ? 15.838  -30.752 53.109  1.00 25.85  ? 131 THR E OG1 1 
ATOM   10146 C  CG2 . THR E 1 131 ? 14.335  -30.768 51.203  1.00 23.29  ? 131 THR E CG2 1 
ATOM   10147 N  N   . PRO E 1 132 ? 15.500  -28.073 49.359  1.00 28.50  ? 132 PRO E N   1 
ATOM   10148 C  CA  . PRO E 1 132 ? 14.852  -27.212 48.358  1.00 29.34  ? 132 PRO E CA  1 
ATOM   10149 C  C   . PRO E 1 132 ? 13.420  -27.650 48.224  1.00 26.06  ? 132 PRO E C   1 
ATOM   10150 O  O   . PRO E 1 132 ? 13.196  -28.817 48.128  1.00 26.78  ? 132 PRO E O   1 
ATOM   10151 C  CB  . PRO E 1 132 ? 15.633  -27.501 47.076  1.00 29.12  ? 132 PRO E CB  1 
ATOM   10152 C  CG  . PRO E 1 132 ? 16.949  -27.949 47.639  1.00 28.17  ? 132 PRO E CG  1 
ATOM   10153 C  CD  . PRO E 1 132 ? 16.591  -28.882 48.790  1.00 25.95  ? 132 PRO E CD  1 
ATOM   10154 N  N   . GLN E 1 133 ? 12.474  -26.744 48.228  1.00 24.47  ? 133 GLN E N   1 
ATOM   10155 C  CA  . GLN E 1 133 ? 11.120  -27.129 47.865  1.00 26.43  ? 133 GLN E CA  1 
ATOM   10156 C  C   . GLN E 1 133 ? 10.705  -26.645 46.469  1.00 25.17  ? 133 GLN E C   1 
ATOM   10157 O  O   . GLN E 1 133 ? 9.830   -27.193 45.885  1.00 27.40  ? 133 GLN E O   1 
ATOM   10158 C  CB  . GLN E 1 133 ? 10.093  -26.438 48.755  1.00 23.51  ? 133 GLN E CB  1 
ATOM   10159 C  CG  . GLN E 1 133 ? 10.227  -26.795 50.225  1.00 32.62  ? 133 GLN E CG  1 
ATOM   10160 C  CD  . GLN E 1 133 ? 9.970   -28.272 50.481  1.00 29.08  ? 133 GLN E CD  1 
ATOM   10161 O  OE1 . GLN E 1 133 ? 9.143   -28.943 49.851  1.00 26.59  ? 133 GLN E OE1 1 
ATOM   10162 N  NE2 . GLN E 1 133 ? 10.815  -28.820 51.322  1.00 29.40  ? 133 GLN E NE2 1 
ATOM   10163 N  N   . ASP E 1 134 ? 11.141  -25.491 46.019  1.00 22.17  ? 134 ASP E N   1 
ATOM   10164 C  CA  . ASP E 1 134 ? 10.828  -25.025 44.691  1.00 25.41  ? 134 ASP E CA  1 
ATOM   10165 C  C   . ASP E 1 134 ? 12.017  -24.213 44.140  1.00 21.54  ? 134 ASP E C   1 
ATOM   10166 O  O   . ASP E 1 134 ? 12.670  -23.510 44.887  1.00 20.98  ? 134 ASP E O   1 
ATOM   10167 C  CB  . ASP E 1 134 ? 9.500   -24.277 44.739  1.00 26.66  ? 134 ASP E CB  1 
ATOM   10168 C  CG  . ASP E 1 134 ? 8.741   -24.182 43.423  1.00 25.07  ? 134 ASP E CG  1 
ATOM   10169 O  OD1 . ASP E 1 134 ? 9.042   -24.955 42.506  1.00 22.56  ? 134 ASP E OD1 1 
ATOM   10170 O  OD2 . ASP E 1 134 ? 7.830   -23.366 43.371  1.00 32.44  ? 134 ASP E OD2 1 
ATOM   10171 N  N   . GLU E 1 135 ? 12.277  -24.327 42.838  1.00 23.22  ? 135 GLU E N   1 
ATOM   10172 C  CA  . GLU E 1 135 ? 13.236  -23.502 42.113  1.00 22.67  ? 135 GLU E CA  1 
ATOM   10173 C  C   . GLU E 1 135 ? 12.599  -23.160 40.771  1.00 20.34  ? 135 GLU E C   1 
ATOM   10174 O  O   . GLU E 1 135 ? 12.255  -24.016 40.041  1.00 20.93  ? 135 GLU E O   1 
ATOM   10175 C  CB  . GLU E 1 135 ? 14.538  -24.261 41.905  1.00 24.36  ? 135 GLU E CB  1 
ATOM   10176 C  CG  . GLU E 1 135 ? 15.584  -23.441 41.145  1.00 28.28  ? 135 GLU E CG  1 
ATOM   10177 C  CD  . GLU E 1 135 ? 16.940  -24.157 40.998  1.00 34.53  ? 135 GLU E CD  1 
ATOM   10178 O  OE1 . GLU E 1 135 ? 17.165  -25.263 41.601  1.00 28.98  ? 135 GLU E OE1 1 
ATOM   10179 O  OE2 . GLU E 1 135 ? 17.805  -23.586 40.272  1.00 32.78  ? 135 GLU E OE2 1 
ATOM   10180 N  N   . VAL E 1 136 ? 12.363  -21.910 40.476  1.00 22.53  ? 136 VAL E N   1 
ATOM   10181 C  CA  . VAL E 1 136 ? 11.805  -21.493 39.213  1.00 22.22  ? 136 VAL E CA  1 
ATOM   10182 C  C   . VAL E 1 136 ? 12.724  -20.410 38.618  1.00 20.31  ? 136 VAL E C   1 
ATOM   10183 O  O   . VAL E 1 136 ? 13.137  -19.472 39.298  1.00 19.13  ? 136 VAL E O   1 
ATOM   10184 C  CB  . VAL E 1 136 ? 10.377  -20.963 39.471  1.00 23.52  ? 136 VAL E CB  1 
ATOM   10185 C  CG1 . VAL E 1 136 ? 9.709   -20.464 38.206  1.00 25.46  ? 136 VAL E CG1 1 
ATOM   10186 C  CG2 . VAL E 1 136 ? 9.490   -22.050 39.972  1.00 27.48  ? 136 VAL E CG2 1 
ATOM   10187 N  N   . HIS E 1 137 ? 12.984  -20.553 37.327  1.00 19.06  ? 137 HIS E N   1 
ATOM   10188 C  CA  . HIS E 1 137 ? 13.763  -19.635 36.507  1.00 22.20  ? 137 HIS E CA  1 
ATOM   10189 C  C   . HIS E 1 137 ? 12.777  -18.922 35.627  1.00 20.75  ? 137 HIS E C   1 
ATOM   10190 O  O   . HIS E 1 137 ? 12.197  -19.552 34.772  1.00 23.12  ? 137 HIS E O   1 
ATOM   10191 C  CB  . HIS E 1 137 ? 14.802  -20.382 35.632  1.00 23.05  ? 137 HIS E CB  1 
ATOM   10192 C  CG  . HIS E 1 137 ? 15.851  -21.071 36.455  1.00 25.78  ? 137 HIS E CG  1 
ATOM   10193 N  ND1 . HIS E 1 137 ? 16.959  -21.620 35.907  1.00 25.75  ? 137 HIS E ND1 1 
ATOM   10194 C  CD2 . HIS E 1 137 ? 15.999  -21.244 37.818  1.00 25.72  ? 137 HIS E CD2 1 
ATOM   10195 C  CE1 . HIS E 1 137 ? 17.649  -22.229 36.878  1.00 25.56  ? 137 HIS E CE1 1 
ATOM   10196 N  NE2 . HIS E 1 137 ? 17.100  -21.960 38.051  1.00 22.71  ? 137 HIS E NE2 1 
ATOM   10197 N  N   . GLY E 1 138 ? 12.547  -17.648 35.889  1.00 20.41  ? 138 GLY E N   1 
ATOM   10198 C  CA  . GLY E 1 138 ? 11.503  -16.938 35.197  1.00 21.73  ? 138 GLY E CA  1 
ATOM   10199 C  C   . GLY E 1 138 ? 12.090  -16.011 34.144  1.00 25.41  ? 138 GLY E C   1 
ATOM   10200 O  O   . GLY E 1 138 ? 13.200  -15.519 34.327  1.00 22.49  ? 138 GLY E O   1 
ATOM   10201 N  N   . PHE E 1 139 ? 11.286  -15.707 33.116  1.00 24.44  ? 139 PHE E N   1 
ATOM   10202 C  CA  . PHE E 1 139 ? 11.673  -14.780 32.067  1.00 23.98  ? 139 PHE E CA  1 
ATOM   10203 C  C   . PHE E 1 139 ? 10.473  -14.023 31.555  1.00 24.96  ? 139 PHE E C   1 
ATOM   10204 O  O   . PHE E 1 139 ? 9.426   -14.597 31.323  1.00 26.29  ? 139 PHE E O   1 
ATOM   10205 C  CB  . PHE E 1 139 ? 12.247  -15.578 30.902  1.00 24.85  ? 139 PHE E CB  1 
ATOM   10206 C  CG  . PHE E 1 139 ? 11.467  -16.807 30.465  1.00 25.48  ? 139 PHE E CG  1 
ATOM   10207 C  CD1 . PHE E 1 139 ? 10.445  -16.710 29.533  1.00 26.38  ? 139 PHE E CD1 1 
ATOM   10208 C  CD2 . PHE E 1 139 ? 11.819  -18.066 30.965  1.00 27.86  ? 139 PHE E CD2 1 
ATOM   10209 C  CE1 . PHE E 1 139 ? 9.742   -17.850 29.153  1.00 27.44  ? 139 PHE E CE1 1 
ATOM   10210 C  CE2 . PHE E 1 139 ? 11.149  -19.221 30.549  1.00 28.71  ? 139 PHE E CE2 1 
ATOM   10211 C  CZ  . PHE E 1 139 ? 10.105  -19.104 29.627  1.00 27.34  ? 139 PHE E CZ  1 
ATOM   10212 N  N   . LYS E 1 140 ? 10.640  -12.710 31.403  1.00 31.39  ? 140 LYS E N   1 
ATOM   10213 C  CA  . LYS E 1 140 ? 9.579   -11.806 30.983  1.00 32.55  ? 140 LYS E CA  1 
ATOM   10214 C  C   . LYS E 1 140 ? 9.580   -11.852 29.464  1.00 32.59  ? 140 LYS E C   1 
ATOM   10215 O  O   . LYS E 1 140 ? 10.631  -11.999 28.903  1.00 26.97  ? 140 LYS E O   1 
ATOM   10216 C  CB  . LYS E 1 140 ? 9.812   -10.405 31.552  1.00 36.15  ? 140 LYS E CB  1 
ATOM   10217 C  CG  . LYS E 1 140 ? 8.562   -9.614  31.937  1.00 52.17  ? 140 LYS E CG  1 
ATOM   10218 C  CD  . LYS E 1 140 ? 7.516   -10.275 32.858  1.00 69.75  ? 140 LYS E CD  1 
ATOM   10219 C  CE  . LYS E 1 140 ? 6.052   -9.882  32.704  1.00 65.41  ? 140 LYS E CE  1 
ATOM   10220 N  NZ  . LYS E 1 140 ? 5.817   -8.547  33.264  1.00 65.88  ? 140 LYS E NZ  1 
ATOM   10221 N  N   . TYR E 1 141 ? 8.414   -11.863 28.815  1.00 31.74  ? 141 TYR E N   1 
ATOM   10222 C  CA  . TYR E 1 141 ? 8.294   -11.704 27.369  1.00 34.55  ? 141 TYR E CA  1 
ATOM   10223 C  C   . TYR E 1 141 ? 8.598   -10.275 26.954  1.00 36.94  ? 141 TYR E C   1 
ATOM   10224 O  O   . TYR E 1 141 ? 8.653   -9.400  27.791  1.00 33.02  ? 141 TYR E O   1 
ATOM   10225 C  CB  . TYR E 1 141 ? 6.922   -12.072 26.825  1.00 31.94  ? 141 TYR E CB  1 
ATOM   10226 C  CG  . TYR E 1 141 ? 6.784   -13.583 26.735  1.00 35.60  ? 141 TYR E CG  1 
ATOM   10227 C  CD1 . TYR E 1 141 ? 6.402   -14.306 27.819  1.00 39.48  ? 141 TYR E CD1 1 
ATOM   10228 C  CD2 . TYR E 1 141 ? 7.080   -14.285 25.578  1.00 45.86  ? 141 TYR E CD2 1 
ATOM   10229 C  CE1 . TYR E 1 141 ? 6.272   -15.685 27.758  1.00 47.31  ? 141 TYR E CE1 1 
ATOM   10230 C  CE2 . TYR E 1 141 ? 6.926   -15.654 25.480  1.00 41.11  ? 141 TYR E CE2 1 
ATOM   10231 C  CZ  . TYR E 1 141 ? 6.549   -16.351 26.591  1.00 43.10  ? 141 TYR E CZ  1 
ATOM   10232 O  OH  . TYR E 1 141 ? 6.422   -17.678 26.599  1.00 44.56  ? 141 TYR E OH  1 
ATOM   10233 N  N   . PHE E 1 142 ? 8.916   -10.053 25.679  1.00 45.83  ? 142 PHE E N   1 
ATOM   10234 C  CA  . PHE E 1 142 ? 9.689   -8.870  25.346  1.00 49.97  ? 142 PHE E CA  1 
ATOM   10235 C  C   . PHE E 1 142 ? 8.811   -7.604  25.434  1.00 53.57  ? 142 PHE E C   1 
ATOM   10236 O  O   . PHE E 1 142 ? 9.407   -6.497  25.535  1.00 47.44  ? 142 PHE E O   1 
ATOM   10237 C  CB  . PHE E 1 142 ? 10.546  -9.086  24.078  1.00 57.29  ? 142 PHE E CB  1 
ATOM   10238 C  CG  . PHE E 1 142 ? 9.824   -8.827  22.770  1.00 59.99  ? 142 PHE E CG  1 
ATOM   10239 C  CD1 . PHE E 1 142 ? 9.022   -9.822  22.203  1.00 72.80  ? 142 PHE E CD1 1 
ATOM   10240 C  CD2 . PHE E 1 142 ? 9.889   -7.566  22.162  1.00 57.83  ? 142 PHE E CD2 1 
ATOM   10241 C  CE1 . PHE E 1 142 ? 8.302   -9.559  21.036  1.00 80.60  ? 142 PHE E CE1 1 
ATOM   10242 C  CE2 . PHE E 1 142 ? 9.192   -7.308  20.983  1.00 65.63  ? 142 PHE E CE2 1 
ATOM   10243 C  CZ  . PHE E 1 142 ? 8.393   -8.301  20.428  1.00 80.29  ? 142 PHE E CZ  1 
ATOM   10244 N  N   . ASP E 1 143 ? 7.445   -7.728  25.507  1.00 42.97  ? 143 ASP E N   1 
ATOM   10245 C  CA  . ASP E 1 143 ? 6.607   -6.517  25.607  1.00 41.14  ? 143 ASP E CA  1 
ATOM   10246 C  C   . ASP E 1 143 ? 5.811   -6.538  26.901  1.00 43.65  ? 143 ASP E C   1 
ATOM   10247 O  O   . ASP E 1 143 ? 4.636   -6.202  26.953  1.00 41.25  ? 143 ASP E O   1 
ATOM   10248 C  CB  . ASP E 1 143 ? 5.701   -6.316  24.406  1.00 45.47  ? 143 ASP E CB  1 
ATOM   10249 C  CG  . ASP E 1 143 ? 5.204   -7.645  23.798  1.00 61.40  ? 143 ASP E CG  1 
ATOM   10250 O  OD1 . ASP E 1 143 ? 5.710   -8.845  24.167  1.00 44.94  ? 143 ASP E OD1 1 
ATOM   10251 O  OD2 . ASP E 1 143 ? 4.263   -7.510  22.950  1.00 57.49  ? 143 ASP E OD2 1 
ATOM   10252 N  N   . GLU E 1 144 ? 6.482   -6.953  27.959  1.00 41.82  ? 144 GLU E N   1 
ATOM   10253 C  CA  . GLU E 1 144 ? 5.912   -7.128  29.292  1.00 39.99  ? 144 GLU E CA  1 
ATOM   10254 C  C   . GLU E 1 144 ? 4.727   -8.097  29.335  1.00 32.52  ? 144 GLU E C   1 
ATOM   10255 O  O   . GLU E 1 144 ? 3.932   -8.020  30.290  1.00 35.57  ? 144 GLU E O   1 
ATOM   10256 C  CB  . GLU E 1 144 ? 5.646   -5.760  29.917  1.00 41.80  ? 144 GLU E CB  1 
ATOM   10257 C  CG  . GLU E 1 144 ? 6.915   -4.938  30.116  1.00 40.36  ? 144 GLU E CG  1 
ATOM   10258 C  CD  . GLU E 1 144 ? 7.796   -5.526  31.207  1.00 41.27  ? 144 GLU E CD  1 
ATOM   10259 O  OE1 . GLU E 1 144 ? 7.201   -6.007  32.166  1.00 42.03  ? 144 GLU E OE1 1 
ATOM   10260 O  OE2 . GLU E 1 144 ? 9.030   -5.519  31.117  1.00 41.25  ? 144 GLU E OE2 1 
ATOM   10261 N  N   . ARG E 1 145 ? 4.674   -9.042  28.380  1.00 27.43  ? 145 ARG E N   1 
ATOM   10262 C  CA  . ARG E 1 145 ? 3.558   -9.970  28.318  1.00 28.35  ? 145 ARG E CA  1 
ATOM   10263 C  C   . ARG E 1 145 ? 3.824   -11.210 29.182  1.00 30.26  ? 145 ARG E C   1 
ATOM   10264 O  O   . ARG E 1 145 ? 4.953   -11.465 29.605  1.00 27.87  ? 145 ARG E O   1 
ATOM   10265 C  CB  . ARG E 1 145 ? 3.191   -10.322 26.881  1.00 27.95  ? 145 ARG E CB  1 
ATOM   10266 C  CG  . ARG E 1 145 ? 2.634   -9.068  26.246  1.00 26.53  ? 145 ARG E CG  1 
ATOM   10267 C  CD  . ARG E 1 145 ? 2.115   -9.385  24.886  1.00 28.11  ? 145 ARG E CD  1 
ATOM   10268 N  NE  . ARG E 1 145 ? 1.782   -8.144  24.165  1.00 33.50  ? 145 ARG E NE  1 
ATOM   10269 C  CZ  . ARG E 1 145 ? 0.599   -7.552  24.129  1.00 33.24  ? 145 ARG E CZ  1 
ATOM   10270 N  NH1 . ARG E 1 145 ? -0.456  -8.102  24.703  1.00 34.36  ? 145 ARG E NH1 1 
ATOM   10271 N  NH2 . ARG E 1 145 ? 0.473   -6.401  23.529  1.00 33.97  ? 145 ARG E NH2 1 
ATOM   10272 N  N   . ASP E 1 146 ? 2.717   -11.874 29.536  1.00 29.03  ? 146 ASP E N   1 
ATOM   10273 C  CA  . ASP E 1 146 ? 2.792   -13.079 30.343  1.00 29.68  ? 146 ASP E CA  1 
ATOM   10274 C  C   . ASP E 1 146 ? 2.450   -14.261 29.471  1.00 25.07  ? 146 ASP E C   1 
ATOM   10275 O  O   . ASP E 1 146 ? 2.343   -14.107 28.265  1.00 20.51  ? 146 ASP E O   1 
ATOM   10276 C  CB  . ASP E 1 146 ? 1.953   -13.038 31.611  1.00 31.77  ? 146 ASP E CB  1 
ATOM   10277 C  CG  . ASP E 1 146 ? 0.476   -12.778 31.375  1.00 28.89  ? 146 ASP E CG  1 
ATOM   10278 O  OD1 . ASP E 1 146 ? 0.004   -13.095 30.288  1.00 24.17  ? 146 ASP E OD1 1 
ATOM   10279 O  OD2 . ASP E 1 146 ? -0.111  -12.200 32.271  1.00 32.00  ? 146 ASP E OD2 1 
ATOM   10280 N  N   . MET E 1 147 ? 2.340   -15.428 30.117  1.00 24.16  ? 147 MET E N   1 
ATOM   10281 C  CA  . MET E 1 147 ? 2.166   -16.644 29.369  1.00 29.48  ? 147 MET E CA  1 
ATOM   10282 C  C   . MET E 1 147 ? 0.830   -16.653 28.632  1.00 24.36  ? 147 MET E C   1 
ATOM   10283 O  O   . MET E 1 147 ? 0.670   -17.422 27.708  1.00 23.17  ? 147 MET E O   1 
ATOM   10284 C  CB  . MET E 1 147 ? 2.320   -17.799 30.353  1.00 33.50  ? 147 MET E CB  1 
ATOM   10285 C  CG  . MET E 1 147 ? 2.540   -19.165 29.745  1.00 33.23  ? 147 MET E CG  1 
ATOM   10286 S  SD  . MET E 1 147 ? 4.013   -19.118 28.742  1.00 33.06  ? 147 MET E SD  1 
ATOM   10287 C  CE  . MET E 1 147 ? 5.357   -19.631 29.820  1.00 33.41  ? 147 MET E CE  1 
ATOM   10288 N  N   . LEU E 1 148 ? -0.137  -15.855 29.071  1.00 25.26  ? 148 LEU E N   1 
ATOM   10289 C  CA  . LEU E 1 148 ? -1.473  -15.802 28.463  1.00 26.02  ? 148 LEU E CA  1 
ATOM   10290 C  C   . LEU E 1 148 ? -1.478  -14.802 27.342  1.00 22.98  ? 148 LEU E C   1 
ATOM   10291 O  O   . LEU E 1 148 ? -2.509  -14.595 26.734  1.00 27.89  ? 148 LEU E O   1 
ATOM   10292 C  CB  . LEU E 1 148 ? -2.560  -15.404 29.474  1.00 25.05  ? 148 LEU E CB  1 
ATOM   10293 C  CG  . LEU E 1 148 ? -2.687  -16.362 30.663  1.00 26.18  ? 148 LEU E CG  1 
ATOM   10294 C  CD1 . LEU E 1 148 ? -3.729  -15.843 31.645  1.00 28.61  ? 148 LEU E CD1 1 
ATOM   10295 C  CD2 . LEU E 1 148 ? -2.963  -17.776 30.229  1.00 23.69  ? 148 LEU E CD2 1 
ATOM   10296 N  N   . GLY E 1 149 ? -0.373  -14.098 27.122  1.00 24.35  ? 149 GLY E N   1 
ATOM   10297 C  CA  . GLY E 1 149 ? -0.366  -13.143 26.010  1.00 21.53  ? 149 GLY E CA  1 
ATOM   10298 C  C   . GLY E 1 149 ? -0.798  -11.721 26.377  1.00 22.68  ? 149 GLY E C   1 
ATOM   10299 O  O   . GLY E 1 149 ? -0.826  -10.863 25.537  1.00 23.01  ? 149 GLY E O   1 
ATOM   10300 N  N   . PHE E 1 150 ? -1.057  -11.428 27.633  1.00 27.61  ? 150 PHE E N   1 
ATOM   10301 C  CA  . PHE E 1 150 ? -1.503  -10.111 28.071  1.00 26.34  ? 150 PHE E CA  1 
ATOM   10302 C  C   . PHE E 1 150 ? -0.358  -9.402  28.782  1.00 27.15  ? 150 PHE E C   1 
ATOM   10303 O  O   . PHE E 1 150 ? 0.476   -10.005 29.452  1.00 27.17  ? 150 PHE E O   1 
ATOM   10304 C  CB  . PHE E 1 150 ? -2.687  -10.228 29.045  1.00 26.58  ? 150 PHE E CB  1 
ATOM   10305 C  CG  . PHE E 1 150 ? -3.998  -10.470 28.320  1.00 24.73  ? 150 PHE E CG  1 
ATOM   10306 C  CD1 . PHE E 1 150 ? -4.227  -11.661 27.646  1.00 26.92  ? 150 PHE E CD1 1 
ATOM   10307 C  CD2 . PHE E 1 150 ? -4.958  -9.468  28.242  1.00 24.71  ? 150 PHE E CD2 1 
ATOM   10308 C  CE1 . PHE E 1 150 ? -5.397  -11.825 26.900  1.00 27.11  ? 150 PHE E CE1 1 
ATOM   10309 C  CE2 . PHE E 1 150 ? -6.120  -9.653  27.501  1.00 25.85  ? 150 PHE E CE2 1 
ATOM   10310 C  CZ  . PHE E 1 150 ? -6.362  -10.841 26.865  1.00 24.68  ? 150 PHE E CZ  1 
ATOM   10311 N  N   . VAL E 1 151 ? -0.344  -8.083  28.625  1.00 29.41  ? 151 VAL E N   1 
ATOM   10312 C  CA  . VAL E 1 151 ? 0.583   -7.270  29.368  1.00 27.54  ? 151 VAL E CA  1 
ATOM   10313 C  C   . VAL E 1 151 ? 0.280   -7.433  30.861  1.00 28.00  ? 151 VAL E C   1 
ATOM   10314 O  O   . VAL E 1 151 ? -0.882  -7.338  31.267  1.00 28.91  ? 151 VAL E O   1 
ATOM   10315 C  CB  . VAL E 1 151 ? 0.450   -5.795  28.917  1.00 26.58  ? 151 VAL E CB  1 
ATOM   10316 C  CG1 . VAL E 1 151 ? 1.394   -4.903  29.698  1.00 25.26  ? 151 VAL E CG1 1 
ATOM   10317 C  CG2 . VAL E 1 151 ? 0.633   -5.632  27.418  1.00 25.74  ? 151 VAL E CG2 1 
ATOM   10318 N  N   . ASP E 1 152 ? 1.330   -7.585  31.657  1.00 29.34  ? 152 ASP E N   1 
ATOM   10319 C  CA  . ASP E 1 152 ? 1.208   -7.969  33.061  1.00 31.51  ? 152 ASP E CA  1 
ATOM   10320 C  C   . ASP E 1 152 ? 2.054   -7.023  33.910  1.00 26.16  ? 152 ASP E C   1 
ATOM   10321 O  O   . ASP E 1 152 ? 3.261   -6.952  33.756  1.00 26.60  ? 152 ASP E O   1 
ATOM   10322 C  CB  . ASP E 1 152 ? 1.649   -9.413  33.183  1.00 34.15  ? 152 ASP E CB  1 
ATOM   10323 C  CG  . ASP E 1 152 ? 1.335   -10.124 34.484  1.00 35.72  ? 152 ASP E CG  1 
ATOM   10324 O  OD1 . ASP E 1 152 ? 1.577   -9.474  35.510  1.00 31.84  ? 152 ASP E OD1 1 
ATOM   10325 O  OD2 . ASP E 1 152 ? 0.935   -11.345 34.410  1.00 35.95  ? 152 ASP E OD2 1 
ATOM   10326 N  N   . GLY E 1 153 ? 1.405   -6.194  34.708  1.00 23.65  ? 153 GLY E N   1 
ATOM   10327 C  CA  . GLY E 1 153 ? 2.140   -5.216  35.522  1.00 23.56  ? 153 GLY E CA  1 
ATOM   10328 C  C   . GLY E 1 153 ? 1.564   -3.798  35.516  1.00 25.86  ? 153 GLY E C   1 
ATOM   10329 O  O   . GLY E 1 153 ? 1.845   -3.025  36.416  1.00 28.82  ? 153 GLY E O   1 
ATOM   10330 N  N   . THR E 1 154 ? 0.790   -3.472  34.479  1.00 25.68  ? 154 THR E N   1 
ATOM   10331 C  CA  . THR E 1 154 ? 0.320   -2.139  34.120  1.00 24.43  ? 154 THR E CA  1 
ATOM   10332 C  C   . THR E 1 154 ? -0.195  -1.374  35.324  1.00 24.37  ? 154 THR E C   1 
ATOM   10333 O  O   . THR E 1 154 ? 0.083   -0.207  35.476  1.00 24.87  ? 154 THR E O   1 
ATOM   10334 C  CB  . THR E 1 154 ? -0.826  -2.358  33.120  1.00 27.62  ? 154 THR E CB  1 
ATOM   10335 O  OG1 . THR E 1 154 ? -0.427  -3.343  32.168  1.00 24.31  ? 154 THR E OG1 1 
ATOM   10336 C  CG2 . THR E 1 154 ? -1.316  -1.056  32.513  1.00 30.38  ? 154 THR E CG2 1 
ATOM   10337 N  N   . GLU E 1 155 ? -1.028  -1.997  36.152  1.00 26.35  ? 155 GLU E N   1 
ATOM   10338 C  CA  . GLU E 1 155 ? -1.718  -1.253  37.205  1.00 28.47  ? 155 GLU E CA  1 
ATOM   10339 C  C   . GLU E 1 155 ? -0.955  -1.311  38.509  1.00 26.67  ? 155 GLU E C   1 
ATOM   10340 O  O   . GLU E 1 155 ? -1.415  -0.800  39.476  1.00 24.63  ? 155 GLU E O   1 
ATOM   10341 C  CB  . GLU E 1 155 ? -3.151  -1.755  37.411  1.00 28.28  ? 155 GLU E CB  1 
ATOM   10342 C  CG  . GLU E 1 155 ? -4.079  -1.229  36.317  1.00 31.29  ? 155 GLU E CG  1 
ATOM   10343 C  CD  . GLU E 1 155 ? -4.161  0.293   36.180  1.00 34.77  ? 155 GLU E CD  1 
ATOM   10344 O  OE1 . GLU E 1 155 ? -4.130  1.000   37.234  1.00 36.87  ? 155 GLU E OE1 1 
ATOM   10345 O  OE2 . GLU E 1 155 ? -4.217  0.773   35.023  1.00 38.04  ? 155 GLU E OE2 1 
ATOM   10346 N  N   . ASN E 1 156 ? 0.247   -1.865  38.549  1.00 32.29  ? 156 ASN E N   1 
ATOM   10347 C  CA  . ASN E 1 156 ? 0.989   -1.833  39.793  1.00 26.18  ? 156 ASN E CA  1 
ATOM   10348 C  C   . ASN E 1 156 ? 1.127   -0.408  40.237  1.00 26.58  ? 156 ASN E C   1 
ATOM   10349 O  O   . ASN E 1 156 ? 1.272   0.435   39.375  1.00 27.77  ? 156 ASN E O   1 
ATOM   10350 C  CB  . ASN E 1 156 ? 2.407   -2.352  39.673  1.00 27.35  ? 156 ASN E CB  1 
ATOM   10351 C  CG  . ASN E 1 156 ? 2.498   -3.828  39.947  1.00 25.88  ? 156 ASN E CG  1 
ATOM   10352 O  OD1 . ASN E 1 156 ? 1.791   -4.398  40.780  1.00 29.27  ? 156 ASN E OD1 1 
ATOM   10353 N  ND2 . ASN E 1 156 ? 3.335   -4.492  39.202  1.00 23.81  ? 156 ASN E ND2 1 
ATOM   10354 N  N   . PRO E 1 157 ? 1.123   -0.100  41.561  1.00 29.33  ? 157 PRO E N   1 
ATOM   10355 C  CA  . PRO E 1 157 ? 1.382   1.275   42.026  1.00 31.04  ? 157 PRO E CA  1 
ATOM   10356 C  C   . PRO E 1 157 ? 2.859   1.610   41.816  1.00 32.09  ? 157 PRO E C   1 
ATOM   10357 O  O   . PRO E 1 157 ? 3.684   0.680   41.650  1.00 34.03  ? 157 PRO E O   1 
ATOM   10358 C  CB  . PRO E 1 157 ? 0.996   1.190   43.522  1.00 33.03  ? 157 PRO E CB  1 
ATOM   10359 C  CG  . PRO E 1 157 ? 1.317   -0.306  43.906  1.00 30.74  ? 157 PRO E CG  1 
ATOM   10360 C  CD  . PRO E 1 157 ? 0.892   -1.067  42.665  1.00 28.33  ? 157 PRO E CD  1 
ATOM   10361 N  N   . THR E 1 158 ? 3.161   2.917   41.786  1.00 32.69  ? 158 THR E N   1 
ATOM   10362 C  CA  . THR E 1 158 ? 4.542   3.401   41.620  1.00 39.47  ? 158 THR E CA  1 
ATOM   10363 C  C   . THR E 1 158 ? 4.847   4.516   42.639  1.00 44.92  ? 158 THR E C   1 
ATOM   10364 O  O   . THR E 1 158 ? 3.925   5.148   43.214  1.00 41.31  ? 158 THR E O   1 
ATOM   10365 C  CB  . THR E 1 158 ? 4.835   3.907   40.204  1.00 39.29  ? 158 THR E CB  1 
ATOM   10366 O  OG1 . THR E 1 158 ? 3.817   4.889   40.041  1.00 34.71  ? 158 THR E OG1 1 
ATOM   10367 C  CG2 . THR E 1 158 ? 4.757   2.819   39.139  1.00 42.69  ? 158 THR E CG2 1 
ATOM   10368 N  N   . GLY E 1 159 ? 6.165   4.692   42.882  1.00 40.65  ? 159 GLY E N   1 
ATOM   10369 C  CA  . GLY E 1 159 ? 6.663   5.767   43.720  1.00 43.08  ? 159 GLY E CA  1 
ATOM   10370 C  C   . GLY E 1 159 ? 5.964   5.800   45.079  1.00 48.41  ? 159 GLY E C   1 
ATOM   10371 O  O   . GLY E 1 159 ? 5.927   4.786   45.761  1.00 48.66  ? 159 GLY E O   1 
ATOM   10372 N  N   . ALA E 1 160 ? 5.433   6.963   45.494  1.00 44.17  ? 160 ALA E N   1 
ATOM   10373 C  CA  . ALA E 1 160 ? 5.000   7.114   46.874  1.00 39.41  ? 160 ALA E CA  1 
ATOM   10374 C  C   . ALA E 1 160 ? 3.812   6.199   47.137  1.00 41.41  ? 160 ALA E C   1 
ATOM   10375 O  O   . ALA E 1 160 ? 3.703   5.613   48.202  1.00 45.68  ? 160 ALA E O   1 
ATOM   10376 C  CB  . ALA E 1 160 ? 4.670   8.559   47.142  1.00 39.50  ? 160 ALA E CB  1 
ATOM   10377 N  N   . ALA E 1 161 ? 2.938   6.011   46.138  1.00 40.81  ? 161 ALA E N   1 
ATOM   10378 C  CA  . ALA E 1 161 ? 1.795   5.130   46.309  1.00 39.61  ? 161 ALA E CA  1 
ATOM   10379 C  C   . ALA E 1 161 ? 2.250   3.679   46.582  1.00 43.14  ? 161 ALA E C   1 
ATOM   10380 O  O   . ALA E 1 161 ? 1.606   2.940   47.356  1.00 42.36  ? 161 ALA E O   1 
ATOM   10381 C  CB  . ALA E 1 161 ? 0.929   5.236   45.100  1.00 35.65  ? 161 ALA E CB  1 
ATOM   10382 N  N   . ALA E 1 162 ? 3.353   3.268   45.926  1.00 33.68  ? 162 ALA E N   1 
ATOM   10383 C  CA  . ALA E 1 162 ? 3.890   1.937   46.148  1.00 37.50  ? 162 ALA E CA  1 
ATOM   10384 C  C   . ALA E 1 162 ? 4.474   1.813   47.559  1.00 38.54  ? 162 ALA E C   1 
ATOM   10385 O  O   . ALA E 1 162 ? 4.133   0.855   48.228  1.00 40.18  ? 162 ALA E O   1 
ATOM   10386 C  CB  . ALA E 1 162 ? 4.897   1.568   45.081  1.00 33.01  ? 162 ALA E CB  1 
ATOM   10387 N  N   . ARG E 1 163 ? 5.350   2.755   47.983  1.00 42.94  ? 163 ARG E N   1 
ATOM   10388 C  CA  . ARG E 1 163 ? 5.881   2.832   49.355  1.00 43.99  ? 163 ARG E CA  1 
ATOM   10389 C  C   . ARG E 1 163 ? 4.693   2.635   50.323  1.00 34.18  ? 163 ARG E C   1 
ATOM   10390 O  O   . ARG E 1 163 ? 4.770   1.769   51.172  1.00 36.40  ? 163 ARG E O   1 
ATOM   10391 C  CB  . ARG E 1 163 ? 6.781   4.069   49.663  1.00 52.22  ? 163 ARG E CB  1 
ATOM   10392 C  CG  . ARG E 1 163 ? 8.254   4.310   49.277  1.00 58.93  ? 163 ARG E CG  1 
ATOM   10393 C  CD  . ARG E 1 163 ? 8.856   5.688   49.816  1.00 50.39  ? 163 ARG E CD  1 
ATOM   10394 N  N   . ARG E 1 164 ? 3.562   3.325   50.119  1.00 33.17  ? 164 ARG E N   1 
ATOM   10395 C  CA  . ARG E 1 164 ? 2.421   3.355   51.039  1.00 41.44  ? 164 ARG E CA  1 
ATOM   10396 C  C   . ARG E 1 164 ? 1.752   1.974   51.002  1.00 44.99  ? 164 ARG E C   1 
ATOM   10397 O  O   . ARG E 1 164 ? 1.248   1.507   52.034  1.00 44.81  ? 164 ARG E O   1 
ATOM   10398 C  CB  . ARG E 1 164 ? 1.466   4.602   50.903  1.00 46.59  ? 164 ARG E CB  1 
ATOM   10399 C  CG  . ARG E 1 164 ? -0.054  4.764   51.166  1.00 38.95  ? 164 ARG E CG  1 
ATOM   10400 N  N   . ALA E 1 165 ? 1.695   1.308   49.841  1.00 30.75  ? 165 ALA E N   1 
ATOM   10401 C  CA  . ALA E 1 165 ? 0.935   0.074   49.809  1.00 28.67  ? 165 ALA E CA  1 
ATOM   10402 C  C   . ALA E 1 165 ? 1.735   -1.132  50.295  1.00 31.91  ? 165 ALA E C   1 
ATOM   10403 O  O   . ALA E 1 165 ? 1.149   -2.140  50.634  1.00 27.58  ? 165 ALA E O   1 
ATOM   10404 C  CB  . ALA E 1 165 ? 0.511   -0.193  48.426  1.00 37.13  ? 165 ALA E CB  1 
ATOM   10405 N  N   . VAL E 1 166 ? 3.072   -1.059  50.279  1.00 33.21  ? 166 VAL E N   1 
ATOM   10406 C  CA  . VAL E 1 166 ? 3.900   -2.250  50.401  1.00 37.18  ? 166 VAL E CA  1 
ATOM   10407 C  C   . VAL E 1 166 ? 4.645   -2.329  51.741  1.00 35.17  ? 166 VAL E C   1 
ATOM   10408 O  O   . VAL E 1 166 ? 4.892   -3.416  52.232  1.00 29.45  ? 166 VAL E O   1 
ATOM   10409 C  CB  . VAL E 1 166 ? 4.894   -2.194  49.214  1.00 40.69  ? 166 VAL E CB  1 
ATOM   10410 C  CG1 . VAL E 1 166 ? 6.098   -3.078  49.456  1.00 45.05  ? 166 VAL E CG1 1 
ATOM   10411 C  CG2 . VAL E 1 166 ? 4.214   -2.550  47.901  1.00 38.06  ? 166 VAL E CG2 1 
ATOM   10412 N  N   . LEU E 1 167 ? 5.112   -1.194  52.286  1.00 36.38  ? 167 LEU E N   1 
ATOM   10413 C  CA  . LEU E 1 167 ? 6.037   -1.181  53.416  1.00 37.12  ? 167 LEU E CA  1 
ATOM   10414 C  C   . LEU E 1 167 ? 5.290   -1.024  54.742  1.00 36.25  ? 167 LEU E C   1 
ATOM   10415 O  O   . LEU E 1 167 ? 4.487   -0.105  54.901  1.00 33.37  ? 167 LEU E O   1 
ATOM   10416 C  CB  . LEU E 1 167 ? 7.058   -0.056  53.267  1.00 36.55  ? 167 LEU E CB  1 
ATOM   10417 C  CG  . LEU E 1 167 ? 7.977   -0.191  52.050  1.00 42.96  ? 167 LEU E CG  1 
ATOM   10418 C  CD1 . LEU E 1 167 ? 9.036   0.869   52.091  1.00 44.54  ? 167 LEU E CD1 1 
ATOM   10419 C  CD2 . LEU E 1 167 ? 8.666   -1.567  51.974  1.00 43.03  ? 167 LEU E CD2 1 
ATOM   10420 N  N   . VAL E 1 168 ? 5.573   -1.944  55.679  1.00 30.75  ? 168 VAL E N   1 
ATOM   10421 C  CA  . VAL E 1 168 ? 5.078   -1.837  57.035  1.00 33.83  ? 168 VAL E CA  1 
ATOM   10422 C  C   . VAL E 1 168 ? 5.507   -0.477  57.580  1.00 29.68  ? 168 VAL E C   1 
ATOM   10423 O  O   . VAL E 1 168 ? 6.625   -0.059  57.389  1.00 33.35  ? 168 VAL E O   1 
ATOM   10424 C  CB  . VAL E 1 168 ? 5.644   -2.994  57.889  1.00 33.37  ? 168 VAL E CB  1 
ATOM   10425 C  CG1 . VAL E 1 168 ? 5.305   -2.853  59.366  1.00 38.30  ? 168 VAL E CG1 1 
ATOM   10426 C  CG2 . VAL E 1 168 ? 5.177   -4.338  57.383  1.00 29.28  ? 168 VAL E CG2 1 
ATOM   10427 N  N   . GLY E 1 169 ? 4.614   0.198   58.277  1.00 34.57  ? 169 GLY E N   1 
ATOM   10428 C  CA  . GLY E 1 169 ? 4.976   1.447   58.917  1.00 38.59  ? 169 GLY E CA  1 
ATOM   10429 C  C   . GLY E 1 169 ? 4.692   1.425   60.421  1.00 47.88  ? 169 GLY E C   1 
ATOM   10430 O  O   . GLY E 1 169 ? 4.998   0.444   61.124  1.00 39.83  ? 169 GLY E O   1 
ATOM   10431 N  N   . ALA E 1 170 ? 4.099   2.551   60.868  1.00 50.61  ? 170 ALA E N   1 
ATOM   10432 C  CA  . ALA E 1 170 ? 3.848   2.880   62.267  1.00 44.39  ? 170 ALA E CA  1 
ATOM   10433 C  C   . ALA E 1 170 ? 2.904   1.879   62.940  1.00 46.97  ? 170 ALA E C   1 
ATOM   10434 O  O   . ALA E 1 170 ? 2.963   1.714   64.154  1.00 56.01  ? 170 ALA E O   1 
ATOM   10435 C  CB  . ALA E 1 170 ? 3.236   4.266   62.294  1.00 39.85  ? 170 ALA E CB  1 
ATOM   10436 N  N   . GLU E 1 171 ? 2.058   1.195   62.160  1.00 40.22  ? 171 GLU E N   1 
ATOM   10437 C  CA  . GLU E 1 171 ? 1.156   0.200   62.718  1.00 36.73  ? 171 GLU E CA  1 
ATOM   10438 C  C   . GLU E 1 171 ? 1.886   -0.987  63.348  1.00 36.75  ? 171 GLU E C   1 
ATOM   10439 O  O   . GLU E 1 171 ? 1.261   -1.774  64.022  1.00 36.73  ? 171 GLU E O   1 
ATOM   10440 C  CB  . GLU E 1 171 ? 0.110   -0.264  61.687  1.00 41.95  ? 171 GLU E CB  1 
ATOM   10441 C  CG  . GLU E 1 171 ? 0.555   -1.246  60.598  1.00 46.04  ? 171 GLU E CG  1 
ATOM   10442 C  CD  . GLU E 1 171 ? 1.438   -0.757  59.449  1.00 46.31  ? 171 GLU E CD  1 
ATOM   10443 O  OE1 . GLU E 1 171 ? 1.792   0.446   59.485  1.00 40.67  ? 171 GLU E OE1 1 
ATOM   10444 O  OE2 . GLU E 1 171 ? 1.775   -1.579  58.539  1.00 40.17  ? 171 GLU E OE2 1 
ATOM   10445 N  N   . ASP E 1 172 ? 3.176   -1.202  63.075  1.00 39.71  ? 172 ASP E N   1 
ATOM   10446 C  CA  . ASP E 1 172 ? 3.911   -2.325  63.648  1.00 34.18  ? 172 ASP E CA  1 
ATOM   10447 C  C   . ASP E 1 172 ? 5.382   -1.921  63.666  1.00 38.10  ? 172 ASP E C   1 
ATOM   10448 O  O   . ASP E 1 172 ? 6.226   -2.406  62.897  1.00 38.53  ? 172 ASP E O   1 
ATOM   10449 C  CB  . ASP E 1 172 ? 3.667   -3.619  62.883  1.00 30.51  ? 172 ASP E CB  1 
ATOM   10450 C  CG  . ASP E 1 172 ? 4.142   -4.872  63.597  1.00 31.74  ? 172 ASP E CG  1 
ATOM   10451 O  OD1 . ASP E 1 172 ? 4.425   -4.746  64.807  1.00 34.00  ? 172 ASP E OD1 1 
ATOM   10452 O  OD2 . ASP E 1 172 ? 4.185   -5.959  62.945  1.00 33.84  ? 172 ASP E OD2 1 
ATOM   10453 N  N   . PRO E 1 173 ? 5.710   -0.945  64.528  1.00 40.85  ? 173 PRO E N   1 
ATOM   10454 C  CA  . PRO E 1 173 ? 6.900   -0.096  64.345  1.00 37.55  ? 173 PRO E CA  1 
ATOM   10455 C  C   . PRO E 1 173 ? 8.226   -0.816  64.467  1.00 34.25  ? 173 PRO E C   1 
ATOM   10456 O  O   . PRO E 1 173 ? 9.253   -0.396  63.914  1.00 34.15  ? 173 PRO E O   1 
ATOM   10457 C  CB  . PRO E 1 173 ? 6.798   0.987   65.425  1.00 40.47  ? 173 PRO E CB  1 
ATOM   10458 C  CG  . PRO E 1 173 ? 5.473   0.722   66.145  1.00 37.57  ? 173 PRO E CG  1 
ATOM   10459 C  CD  . PRO E 1 173 ? 4.902   -0.611  65.706  1.00 37.77  ? 173 PRO E CD  1 
ATOM   10460 N  N   . ALA E 1 174 ? 8.245   -1.886  65.256  1.00 29.93  ? 174 ALA E N   1 
ATOM   10461 C  CA  . ALA E 1 174 ? 9.471   -2.650  65.346  1.00 27.83  ? 174 ALA E CA  1 
ATOM   10462 C  C   . ALA E 1 174 ? 9.839   -3.288  63.994  1.00 31.12  ? 174 ALA E C   1 
ATOM   10463 O  O   . ALA E 1 174 ? 10.982  -3.700  63.851  1.00 37.97  ? 174 ALA E O   1 
ATOM   10464 C  CB  . ALA E 1 174 ? 9.261   -3.703  66.392  1.00 33.39  ? 174 ALA E CB  1 
ATOM   10465 N  N   . PHE E 1 175 ? 8.876   -3.447  63.052  1.00 31.12  ? 175 PHE E N   1 
ATOM   10466 C  CA  . PHE E 1 175 ? 9.074   -4.147  61.782  1.00 31.47  ? 175 PHE E CA  1 
ATOM   10467 C  C   . PHE E 1 175 ? 8.845   -3.212  60.589  1.00 31.86  ? 175 PHE E C   1 
ATOM   10468 O  O   . PHE E 1 175 ? 8.791   -3.668  59.462  1.00 28.92  ? 175 PHE E O   1 
ATOM   10469 C  CB  . PHE E 1 175 ? 8.156   -5.365  61.720  1.00 30.84  ? 175 PHE E CB  1 
ATOM   10470 C  CG  . PHE E 1 175 ? 8.573   -6.361  62.775  1.00 33.64  ? 175 PHE E CG  1 
ATOM   10471 C  CD1 . PHE E 1 175 ? 9.775   -7.029  62.673  1.00 35.10  ? 175 PHE E CD1 1 
ATOM   10472 C  CD2 . PHE E 1 175 ? 7.802   -6.596  63.900  1.00 42.06  ? 175 PHE E CD2 1 
ATOM   10473 C  CE1 . PHE E 1 175 ? 10.184  -7.931  63.646  1.00 30.32  ? 175 PHE E CE1 1 
ATOM   10474 C  CE2 . PHE E 1 175 ? 8.238   -7.498  64.869  1.00 36.49  ? 175 PHE E CE2 1 
ATOM   10475 C  CZ  . PHE E 1 175 ? 9.415   -8.178  64.716  1.00 30.56  ? 175 PHE E CZ  1 
ATOM   10476 N  N   . ALA E 1 176 ? 8.763   -1.890  60.828  1.00 36.29  ? 176 ALA E N   1 
ATOM   10477 C  CA  . ALA E 1 176 ? 8.708   -0.888  59.761  1.00 34.98  ? 176 ALA E CA  1 
ATOM   10478 C  C   . ALA E 1 176 ? 9.802   -1.123  58.717  1.00 34.04  ? 176 ALA E C   1 
ATOM   10479 O  O   . ALA E 1 176 ? 10.958  -1.422  59.013  1.00 37.73  ? 176 ALA E O   1 
ATOM   10480 C  CB  . ALA E 1 176 ? 8.834   0.521   60.317  1.00 28.30  ? 176 ALA E CB  1 
ATOM   10481 N  N   . GLY E 1 177 ? 9.398   -1.049  57.459  1.00 33.42  ? 177 GLY E N   1 
ATOM   10482 C  CA  . GLY E 1 177 ? 10.303  -1.275  56.335  1.00 37.52  ? 177 GLY E CA  1 
ATOM   10483 C  C   . GLY E 1 177 ? 10.213  -2.685  55.751  1.00 33.86  ? 177 GLY E C   1 
ATOM   10484 O  O   . GLY E 1 177 ? 10.873  -3.020  54.739  1.00 33.22  ? 177 GLY E O   1 
ATOM   10485 N  N   . GLY E 1 178 ? 9.469   -3.539  56.461  1.00 32.59  ? 178 GLY E N   1 
ATOM   10486 C  CA  . GLY E 1 178 ? 9.264   -4.909  56.016  1.00 31.96  ? 178 GLY E CA  1 
ATOM   10487 C  C   . GLY E 1 178 ? 8.088   -4.941  55.066  1.00 26.78  ? 178 GLY E C   1 
ATOM   10488 O  O   . GLY E 1 178 ? 7.505   -3.905  54.731  1.00 24.63  ? 178 GLY E O   1 
ATOM   10489 N  N   . SER E 1 179 ? 7.779   -6.141  54.620  1.00 24.56  ? 179 SER E N   1 
ATOM   10490 C  CA  . SER E 1 179 ? 6.650   -6.325  53.726  1.00 26.21  ? 179 SER E CA  1 
ATOM   10491 C  C   . SER E 1 179 ? 6.223   -7.786  53.809  1.00 24.99  ? 179 SER E C   1 
ATOM   10492 O  O   . SER E 1 179 ? 6.886   -8.612  54.459  1.00 25.50  ? 179 SER E O   1 
ATOM   10493 C  CB  . SER E 1 179 ? 6.962   -5.905  52.313  1.00 24.99  ? 179 SER E CB  1 
ATOM   10494 O  OG  . SER E 1 179 ? 5.792   -5.854  51.519  1.00 25.96  ? 179 SER E OG  1 
ATOM   10495 N  N   . TYR E 1 180 ? 5.059   -8.072  53.225  1.00 25.07  ? 180 TYR E N   1 
ATOM   10496 C  CA  . TYR E 1 180 ? 4.574   -9.427  53.285  1.00 28.89  ? 180 TYR E CA  1 
ATOM   10497 C  C   . TYR E 1 180 ? 4.484   -9.907  51.860  1.00 28.65  ? 180 TYR E C   1 
ATOM   10498 O  O   . TYR E 1 180 ? 3.815   -9.246  51.058  1.00 25.92  ? 180 TYR E O   1 
ATOM   10499 C  CB  . TYR E 1 180 ? 3.215   -9.547  54.006  1.00 35.22  ? 180 TYR E CB  1 
ATOM   10500 C  CG  . TYR E 1 180 ? 3.248   -9.292  55.501  1.00 29.33  ? 180 TYR E CG  1 
ATOM   10501 C  CD1 . TYR E 1 180 ? 3.208   -7.997  55.983  1.00 29.34  ? 180 TYR E CD1 1 
ATOM   10502 C  CD2 . TYR E 1 180 ? 3.390   -10.326 56.395  1.00 28.85  ? 180 TYR E CD2 1 
ATOM   10503 C  CE1 . TYR E 1 180 ? 3.232   -7.751  57.344  1.00 31.20  ? 180 TYR E CE1 1 
ATOM   10504 C  CE2 . TYR E 1 180 ? 3.463   -10.090 57.771  1.00 28.93  ? 180 TYR E CE2 1 
ATOM   10505 C  CZ  . TYR E 1 180 ? 3.342   -8.802  58.237  1.00 25.12  ? 180 TYR E CZ  1 
ATOM   10506 O  OH  . TYR E 1 180 ? 3.402   -8.489  59.536  1.00 25.08  ? 180 TYR E OH  1 
ATOM   10507 N  N   . ALA E 1 181 ? 5.023   -11.116 51.642  1.00 25.97  ? 181 ALA E N   1 
ATOM   10508 C  CA  . ALA E 1 181 ? 5.032   -11.690 50.313  1.00 28.60  ? 181 ALA E CA  1 
ATOM   10509 C  C   . ALA E 1 181 ? 4.241   -12.989 50.287  1.00 25.53  ? 181 ALA E C   1 
ATOM   10510 O  O   . ALA E 1 181 ? 4.460   -13.872 51.121  1.00 27.30  ? 181 ALA E O   1 
ATOM   10511 C  CB  . ALA E 1 181 ? 6.464   -11.949 49.869  1.00 31.26  ? 181 ALA E CB  1 
ATOM   10512 N  N   . VAL E 1 182 ? 3.409   -13.098 49.260  1.00 23.17  ? 182 VAL E N   1 
ATOM   10513 C  CA  . VAL E 1 182 ? 2.690   -14.319 48.983  1.00 24.38  ? 182 VAL E CA  1 
ATOM   10514 C  C   . VAL E 1 182 ? 3.168   -14.844 47.639  1.00 22.50  ? 182 VAL E C   1 
ATOM   10515 O  O   . VAL E 1 182 ? 3.143   -14.104 46.670  1.00 20.20  ? 182 VAL E O   1 
ATOM   10516 C  CB  . VAL E 1 182 ? 1.163   -14.065 48.947  1.00 24.59  ? 182 VAL E CB  1 
ATOM   10517 C  CG1 . VAL E 1 182 ? 0.409   -15.286 48.485  1.00 27.09  ? 182 VAL E CG1 1 
ATOM   10518 C  CG2 . VAL E 1 182 ? 0.601   -13.606 50.282  1.00 26.55  ? 182 VAL E CG2 1 
ATOM   10519 N  N   . VAL E 1 183 ? 3.461   -16.139 47.574  1.00 23.59  ? 183 VAL E N   1 
ATOM   10520 C  CA  . VAL E 1 183 ? 3.832   -16.758 46.323  1.00 25.02  ? 183 VAL E CA  1 
ATOM   10521 C  C   . VAL E 1 183 ? 2.847   -17.863 46.004  1.00 26.39  ? 183 VAL E C   1 
ATOM   10522 O  O   . VAL E 1 183 ? 2.405   -18.531 46.922  1.00 24.23  ? 183 VAL E O   1 
ATOM   10523 C  CB  . VAL E 1 183 ? 5.260   -17.340 46.296  1.00 23.22  ? 183 VAL E CB  1 
ATOM   10524 C  CG1 . VAL E 1 183 ? 6.274   -16.234 46.480  1.00 27.99  ? 183 VAL E CG1 1 
ATOM   10525 C  CG2 . VAL E 1 183 ? 5.499   -18.397 47.333  1.00 22.79  ? 183 VAL E CG2 1 
ATOM   10526 N  N   . GLN E 1 184 ? 2.553   -18.025 44.708  1.00 24.69  ? 184 GLN E N   1 
ATOM   10527 C  CA  . GLN E 1 184 ? 1.892   -19.220 44.211  1.00 23.90  ? 184 GLN E CA  1 
ATOM   10528 C  C   . GLN E 1 184 ? 2.405   -19.527 42.800  1.00 24.18  ? 184 GLN E C   1 
ATOM   10529 O  O   . GLN E 1 184 ? 2.441   -18.664 41.921  1.00 21.10  ? 184 GLN E O   1 
ATOM   10530 C  CB  . GLN E 1 184 ? 0.369   -19.133 44.045  1.00 27.04  ? 184 GLN E CB  1 
ATOM   10531 C  CG  . GLN E 1 184 ? -0.455  -18.565 45.207  1.00 31.49  ? 184 GLN E CG  1 
ATOM   10532 C  CD  . GLN E 1 184 ? -1.904  -18.234 44.830  1.00 29.92  ? 184 GLN E CD  1 
ATOM   10533 O  OE1 . GLN E 1 184 ? -2.232  -17.219 44.213  1.00 21.66  ? 184 GLN E OE1 1 
ATOM   10534 N  NE2 . GLN E 1 184 ? -2.828  -19.130 45.131  1.00 28.35  ? 184 GLN E NE2 1 
ATOM   10535 N  N   . LYS E 1 185 ? 2.728   -20.797 42.571  1.00 21.80  ? 185 LYS E N   1 
ATOM   10536 C  CA  . LYS E 1 185 ? 3.092   -21.258 41.256  1.00 21.16  ? 185 LYS E CA  1 
ATOM   10537 C  C   . LYS E 1 185 ? 1.843   -21.715 40.527  1.00 22.42  ? 185 LYS E C   1 
ATOM   10538 O  O   . LYS E 1 185 ? 1.115   -22.535 41.060  1.00 28.06  ? 185 LYS E O   1 
ATOM   10539 C  CB  . LYS E 1 185 ? 4.113   -22.376 41.394  1.00 20.58  ? 185 LYS E CB  1 
ATOM   10540 C  CG  . LYS E 1 185 ? 4.568   -22.935 40.091  1.00 24.27  ? 185 LYS E CG  1 
ATOM   10541 C  CD  . LYS E 1 185 ? 5.942   -23.577 40.103  1.00 27.75  ? 185 LYS E CD  1 
ATOM   10542 C  CE  . LYS E 1 185 ? 5.869   -24.875 40.778  1.00 30.03  ? 185 LYS E CE  1 
ATOM   10543 N  NZ  . LYS E 1 185 ? 7.185   -25.468 40.676  1.00 29.11  ? 185 LYS E NZ  1 
ATOM   10544 N  N   . TYR E 1 186 ? 1.537   -21.118 39.371  1.00 21.78  ? 186 TYR E N   1 
ATOM   10545 C  CA  . TYR E 1 186 ? 0.375   -21.483 38.553  1.00 20.66  ? 186 TYR E CA  1 
ATOM   10546 C  C   . TYR E 1 186 ? 0.823   -22.182 37.272  1.00 24.88  ? 186 TYR E C   1 
ATOM   10547 O  O   . TYR E 1 186 ? 1.805   -21.782 36.641  1.00 29.60  ? 186 TYR E O   1 
ATOM   10548 C  CB  . TYR E 1 186 ? -0.428  -20.279 38.121  1.00 20.21  ? 186 TYR E CB  1 
ATOM   10549 C  CG  . TYR E 1 186 ? -1.313  -19.670 39.192  1.00 21.83  ? 186 TYR E CG  1 
ATOM   10550 C  CD1 . TYR E 1 186 ? -2.610  -20.169 39.455  1.00 24.79  ? 186 TYR E CD1 1 
ATOM   10551 C  CD2 . TYR E 1 186 ? -0.849  -18.626 39.972  1.00 23.25  ? 186 TYR E CD2 1 
ATOM   10552 C  CE1 . TYR E 1 186 ? -3.377  -19.631 40.470  1.00 24.93  ? 186 TYR E CE1 1 
ATOM   10553 C  CE2 . TYR E 1 186 ? -1.593  -18.121 41.019  1.00 25.19  ? 186 TYR E CE2 1 
ATOM   10554 C  CZ  . TYR E 1 186 ? -2.887  -18.573 41.226  1.00 27.46  ? 186 TYR E CZ  1 
ATOM   10555 O  OH  . TYR E 1 186 ? -3.575  -17.971 42.219  1.00 31.29  ? 186 TYR E OH  1 
ATOM   10556 N  N   . LEU E 1 187 ? 0.138   -23.265 36.917  1.00 23.24  ? 187 LEU E N   1 
ATOM   10557 C  CA  . LEU E 1 187 ? 0.308   -23.899 35.625  1.00 23.18  ? 187 LEU E CA  1 
ATOM   10558 C  C   . LEU E 1 187 ? -0.918  -23.623 34.777  1.00 27.11  ? 187 LEU E C   1 
ATOM   10559 O  O   . LEU E 1 187 ? -2.016  -23.585 35.305  1.00 27.84  ? 187 LEU E O   1 
ATOM   10560 C  CB  . LEU E 1 187 ? 0.548   -25.382 35.798  1.00 24.28  ? 187 LEU E CB  1 
ATOM   10561 C  CG  . LEU E 1 187 ? 1.854   -25.717 36.520  1.00 30.93  ? 187 LEU E CG  1 
ATOM   10562 C  CD1 . LEU E 1 187 ? 1.856   -27.163 36.967  1.00 30.36  ? 187 LEU E CD1 1 
ATOM   10563 C  CD2 . LEU E 1 187 ? 3.054   -25.392 35.624  1.00 36.59  ? 187 LEU E CD2 1 
ATOM   10564 N  N   . HIS E 1 188 ? -0.711  -23.352 33.496  1.00 25.35  ? 188 HIS E N   1 
ATOM   10565 C  CA  . HIS E 1 188 ? -1.796  -22.958 32.638  1.00 22.90  ? 188 HIS E CA  1 
ATOM   10566 C  C   . HIS E 1 188 ? -2.135  -24.085 31.681  1.00 26.79  ? 188 HIS E C   1 
ATOM   10567 O  O   . HIS E 1 188 ? -1.299  -24.875 31.279  1.00 29.72  ? 188 HIS E O   1 
ATOM   10568 C  CB  . HIS E 1 188 ? -1.423  -21.741 31.798  1.00 23.27  ? 188 HIS E CB  1 
ATOM   10569 C  CG  . HIS E 1 188 ? -1.231  -20.527 32.604  1.00 22.39  ? 188 HIS E CG  1 
ATOM   10570 N  ND1 . HIS E 1 188 ? -2.268  -19.907 33.260  1.00 23.83  ? 188 HIS E ND1 1 
ATOM   10571 C  CD2 . HIS E 1 188 ? -0.149  -19.799 32.819  1.00 22.19  ? 188 HIS E CD2 1 
ATOM   10572 C  CE1 . HIS E 1 188 ? -1.817  -18.821 33.869  1.00 27.28  ? 188 HIS E CE1 1 
ATOM   10573 N  NE2 . HIS E 1 188 ? -0.515  -18.716 33.589  1.00 24.16  ? 188 HIS E NE2 1 
ATOM   10574 N  N   . ASP E 1 189 ? -3.384  -24.088 31.244  1.00 31.22  ? 189 ASP E N   1 
ATOM   10575 C  CA  . ASP E 1 189 ? -3.854  -24.951 30.179  1.00 29.46  ? 189 ASP E CA  1 
ATOM   10576 C  C   . ASP E 1 189 ? -3.875  -24.097 28.930  1.00 29.91  ? 189 ASP E C   1 
ATOM   10577 O  O   . ASP E 1 189 ? -4.848  -23.385 28.628  1.00 30.19  ? 189 ASP E O   1 
ATOM   10578 C  CB  . ASP E 1 189 ? -5.237  -25.496 30.512  1.00 33.67  ? 189 ASP E CB  1 
ATOM   10579 C  CG  . ASP E 1 189 ? -5.781  -26.515 29.532  1.00 33.07  ? 189 ASP E CG  1 
ATOM   10580 O  OD1 . ASP E 1 189 ? -5.233  -26.637 28.399  1.00 31.38  ? 189 ASP E OD1 1 
ATOM   10581 O  OD2 . ASP E 1 189 ? -6.730  -27.176 29.961  1.00 37.00  ? 189 ASP E OD2 1 
ATOM   10582 N  N   . ILE E 1 190 ? -2.760  -24.144 28.223  1.00 32.01  ? 190 ILE E N   1 
ATOM   10583 C  CA  . ILE E 1 190 ? -2.564  -23.261 27.099  1.00 30.63  ? 190 ILE E CA  1 
ATOM   10584 C  C   . ILE E 1 190 ? -3.473  -23.673 25.950  1.00 29.14  ? 190 ILE E C   1 
ATOM   10585 O  O   . ILE E 1 190 ? -4.027  -22.788 25.305  1.00 31.74  ? 190 ILE E O   1 
ATOM   10586 C  CB  . ILE E 1 190 ? -1.064  -23.212 26.759  1.00 36.92  ? 190 ILE E CB  1 
ATOM   10587 C  CG1 . ILE E 1 190 ? -0.295  -22.346 27.776  1.00 37.01  ? 190 ILE E CG1 1 
ATOM   10588 C  CG2 . ILE E 1 190 ? -0.851  -22.627 25.387  1.00 42.75  ? 190 ILE E CG2 1 
ATOM   10589 C  CD1 . ILE E 1 190 ? -0.770  -20.896 27.870  1.00 34.10  ? 190 ILE E CD1 1 
ATOM   10590 N  N   . ASP E 1 191 ? -3.738  -24.977 25.776  1.00 31.88  ? 191 ASP E N   1 
ATOM   10591 C  CA  . ASP E 1 191 ? -4.599  -25.446 24.690  1.00 30.29  ? 191 ASP E CA  1 
ATOM   10592 C  C   . ASP E 1 191 ? -5.996  -24.903 24.891  1.00 29.06  ? 191 ASP E C   1 
ATOM   10593 O  O   . ASP E 1 191 ? -6.554  -24.341 23.995  1.00 31.62  ? 191 ASP E O   1 
ATOM   10594 C  CB  . ASP E 1 191 ? -4.745  -26.951 24.660  1.00 34.16  ? 191 ASP E CB  1 
ATOM   10595 C  CG  . ASP E 1 191 ? -3.473  -27.700 24.365  1.00 41.11  ? 191 ASP E CG  1 
ATOM   10596 O  OD1 . ASP E 1 191 ? -2.582  -27.109 23.751  1.00 41.84  ? 191 ASP E OD1 1 
ATOM   10597 O  OD2 . ASP E 1 191 ? -3.439  -28.880 24.690  1.00 67.12  ? 191 ASP E OD2 1 
ATOM   10598 N  N   . ALA E 1 192 ? -6.518  -24.979 26.102  1.00 25.12  ? 192 ALA E N   1 
ATOM   10599 C  CA  . ALA E 1 192 ? -7.823  -24.412 26.351  1.00 25.01  ? 192 ALA E CA  1 
ATOM   10600 C  C   . ALA E 1 192 ? -7.847  -22.921 26.053  1.00 28.08  ? 192 ALA E C   1 
ATOM   10601 O  O   . ALA E 1 192 ? -8.822  -22.416 25.511  1.00 33.12  ? 192 ALA E O   1 
ATOM   10602 C  CB  . ALA E 1 192 ? -8.243  -24.680 27.792  1.00 24.86  ? 192 ALA E CB  1 
ATOM   10603 N  N   . TRP E 1 193 ? -6.849  -22.192 26.548  1.00 28.95  ? 193 TRP E N   1 
ATOM   10604 C  CA  . TRP E 1 193 ? -6.815  -20.737 26.487  1.00 27.00  ? 193 TRP E CA  1 
ATOM   10605 C  C   . TRP E 1 193 ? -6.764  -20.260 25.043  1.00 28.07  ? 193 TRP E C   1 
ATOM   10606 O  O   . TRP E 1 193 ? -7.443  -19.299 24.650  1.00 23.99  ? 193 TRP E O   1 
ATOM   10607 C  CB  . TRP E 1 193 ? -5.569  -20.252 27.229  1.00 26.50  ? 193 TRP E CB  1 
ATOM   10608 C  CG  . TRP E 1 193 ? -5.396  -18.763 27.235  1.00 24.66  ? 193 TRP E CG  1 
ATOM   10609 C  CD1 . TRP E 1 193 ? -4.413  -18.081 26.636  1.00 26.31  ? 193 TRP E CD1 1 
ATOM   10610 C  CD2 . TRP E 1 193 ? -6.227  -17.784 27.876  1.00 24.99  ? 193 TRP E CD2 1 
ATOM   10611 N  NE1 . TRP E 1 193 ? -4.558  -16.748 26.900  1.00 26.15  ? 193 TRP E NE1 1 
ATOM   10612 C  CE2 . TRP E 1 193 ? -5.674  -16.533 27.619  1.00 22.13  ? 193 TRP E CE2 1 
ATOM   10613 C  CE3 . TRP E 1 193 ? -7.402  -17.858 28.617  1.00 27.24  ? 193 TRP E CE3 1 
ATOM   10614 C  CZ2 . TRP E 1 193 ? -6.217  -15.358 28.079  1.00 23.64  ? 193 TRP E CZ2 1 
ATOM   10615 C  CZ3 . TRP E 1 193 ? -7.943  -16.690 29.094  1.00 28.35  ? 193 TRP E CZ3 1 
ATOM   10616 C  CH2 . TRP E 1 193 ? -7.345  -15.460 28.841  1.00 26.24  ? 193 TRP E CH2 1 
ATOM   10617 N  N   . GLU E 1 194 ? -5.989  -21.008 24.251  1.00 35.16  ? 194 GLU E N   1 
ATOM   10618 C  CA  . GLU E 1 194 ? -5.788  -20.660 22.849  1.00 42.81  ? 194 GLU E CA  1 
ATOM   10619 C  C   . GLU E 1 194 ? -6.990  -21.053 22.014  1.00 34.23  ? 194 GLU E C   1 
ATOM   10620 O  O   . GLU E 1 194 ? -7.133  -20.614 20.905  1.00 36.66  ? 194 GLU E O   1 
ATOM   10621 C  CB  . GLU E 1 194 ? -4.412  -21.073 22.328  1.00 44.15  ? 194 GLU E CB  1 
ATOM   10622 C  CG  . GLU E 1 194 ? -3.467  -19.891 22.559  1.00 61.31  ? 194 GLU E CG  1 
ATOM   10623 C  CD  . GLU E 1 194 ? -2.017  -20.265 22.546  1.00 70.04  ? 194 GLU E CD  1 
ATOM   10624 O  OE1 . GLU E 1 194 ? -1.693  -21.297 21.914  1.00 70.89  ? 194 GLU E OE1 1 
ATOM   10625 O  OE2 . GLU E 1 194 ? -1.250  -19.544 23.218  1.00 74.37  ? 194 GLU E OE2 1 
ATOM   10626 N  N   . GLY E 1 195 ? -7.927  -21.801 22.561  1.00 37.57  ? 195 GLY E N   1 
ATOM   10627 C  CA  . GLY E 1 195 ? -9.148  -22.027 21.816  1.00 37.39  ? 195 GLY E CA  1 
ATOM   10628 C  C   . GLY E 1 195 ? -10.130 -20.867 21.954  1.00 34.78  ? 195 GLY E C   1 
ATOM   10629 O  O   . GLY E 1 195 ? -11.135 -20.865 21.283  1.00 40.68  ? 195 GLY E O   1 
ATOM   10630 N  N   . LEU E 1 196 ? -9.907  -19.931 22.877  1.00 28.22  ? 196 LEU E N   1 
ATOM   10631 C  CA  . LEU E 1 196 ? -10.800 -18.804 22.964  1.00 30.74  ? 196 LEU E CA  1 
ATOM   10632 C  C   . LEU E 1 196 ? -10.457 -17.793 21.862  1.00 31.92  ? 196 LEU E C   1 
ATOM   10633 O  O   . LEU E 1 196 ? -9.308  -17.629 21.456  1.00 27.43  ? 196 LEU E O   1 
ATOM   10634 C  CB  . LEU E 1 196 ? -10.669 -18.189 24.352  1.00 33.83  ? 196 LEU E CB  1 
ATOM   10635 C  CG  . LEU E 1 196 ? -11.737 -18.595 25.367  1.00 35.88  ? 196 LEU E CG  1 
ATOM   10636 C  CD1 . LEU E 1 196 ? -11.883 -20.116 25.348  1.00 37.15  ? 196 LEU E CD1 1 
ATOM   10637 C  CD2 . LEU E 1 196 ? -11.411 -18.025 26.739  1.00 34.14  ? 196 LEU E CD2 1 
ATOM   10638 N  N   . SER E 1 197 ? -11.468 -17.072 21.413  1.00 26.10  ? 197 SER E N   1 
ATOM   10639 C  CA  . SER E 1 197 ? -11.195 -15.890 20.638  1.00 31.47  ? 197 SER E CA  1 
ATOM   10640 C  C   . SER E 1 197 ? -10.503 -14.809 21.507  1.00 34.37  ? 197 SER E C   1 
ATOM   10641 O  O   . SER E 1 197 ? -10.648 -14.781 22.725  1.00 27.71  ? 197 SER E O   1 
ATOM   10642 C  CB  . SER E 1 197 ? -12.499 -15.384 20.054  1.00 27.01  ? 197 SER E CB  1 
ATOM   10643 O  OG  . SER E 1 197 ? -13.213 -14.753 21.101  1.00 25.44  ? 197 SER E OG  1 
ATOM   10644 N  N   . VAL E 1 198 ? -9.837  -13.850 20.851  1.00 30.74  ? 198 VAL E N   1 
ATOM   10645 C  CA  . VAL E 1 198 ? -9.304  -12.700 21.539  1.00 28.10  ? 198 VAL E CA  1 
ATOM   10646 C  C   . VAL E 1 198 ? -10.393 -11.978 22.321  1.00 29.66  ? 198 VAL E C   1 
ATOM   10647 O  O   . VAL E 1 198 ? -10.118 -11.572 23.458  1.00 28.41  ? 198 VAL E O   1 
ATOM   10648 C  CB  . VAL E 1 198 ? -8.523  -11.761 20.610  1.00 29.62  ? 198 VAL E CB  1 
ATOM   10649 C  CG1 . VAL E 1 198 ? -8.194  -10.417 21.283  1.00 28.79  ? 198 VAL E CG1 1 
ATOM   10650 C  CG2 . VAL E 1 198 ? -7.219  -12.442 20.185  1.00 29.06  ? 198 VAL E CG2 1 
ATOM   10651 N  N   . GLU E 1 199 ? -11.615 -11.840 21.780  1.00 28.80  ? 199 GLU E N   1 
ATOM   10652 C  CA  . GLU E 1 199 ? -12.639 -11.041 22.470  1.00 30.39  ? 199 GLU E CA  1 
ATOM   10653 C  C   . GLU E 1 199 ? -13.005 -11.781 23.754  1.00 29.43  ? 199 GLU E C   1 
ATOM   10654 O  O   . GLU E 1 199 ? -13.096 -11.165 24.810  1.00 32.56  ? 199 GLU E O   1 
ATOM   10655 C  CB  . GLU E 1 199 ? -13.834 -10.597 21.600  1.00 34.96  ? 199 GLU E CB  1 
ATOM   10656 C  CG  . GLU E 1 199 ? -13.456 -9.700  20.397  1.00 43.95  ? 199 GLU E CG  1 
ATOM   10657 C  CD  . GLU E 1 199 ? -12.577 -10.281 19.214  1.00 50.71  ? 199 GLU E CD  1 
ATOM   10658 O  OE1 . GLU E 1 199 ? -12.530 -11.589 18.954  1.00 33.77  ? 199 GLU E OE1 1 
ATOM   10659 O  OE2 . GLU E 1 199 ? -11.908 -9.378  18.545  1.00 28.74  ? 199 GLU E OE2 1 
ATOM   10660 N  N   . ALA E 1 200 ? -13.071 -13.108 23.701  1.00 27.50  ? 200 ALA E N   1 
ATOM   10661 C  CA  . ALA E 1 200 ? -13.375 -13.913 24.883  1.00 30.62  ? 200 ALA E CA  1 
ATOM   10662 C  C   . ALA E 1 200 ? -12.287 -13.823 25.957  1.00 35.98  ? 200 ALA E C   1 
ATOM   10663 O  O   . ALA E 1 200 ? -12.584 -13.846 27.180  1.00 38.73  ? 200 ALA E O   1 
ATOM   10664 C  CB  . ALA E 1 200 ? -13.534 -15.392 24.505  1.00 27.82  ? 200 ALA E CB  1 
ATOM   10665 N  N   . GLN E 1 201 ? -11.016 -13.850 25.494  1.00 27.86  ? 201 GLN E N   1 
ATOM   10666 C  CA  . GLN E 1 201 ? -9.922  -13.749 26.445  1.00 26.69  ? 201 GLN E CA  1 
ATOM   10667 C  C   . GLN E 1 201 ? -9.981  -12.381 27.125  1.00 24.43  ? 201 GLN E C   1 
ATOM   10668 O  O   . GLN E 1 201 ? -9.681  -12.265 28.310  1.00 23.00  ? 201 GLN E O   1 
ATOM   10669 C  CB  . GLN E 1 201 ? -8.602  -13.900 25.721  1.00 25.15  ? 201 GLN E CB  1 
ATOM   10670 C  CG  . GLN E 1 201 ? -8.320  -15.277 25.166  1.00 23.85  ? 201 GLN E CG  1 
ATOM   10671 C  CD  . GLN E 1 201 ? -6.971  -15.333 24.475  1.00 24.36  ? 201 GLN E CD  1 
ATOM   10672 O  OE1 . GLN E 1 201 ? -6.280  -14.327 24.247  1.00 24.44  ? 201 GLN E OE1 1 
ATOM   10673 N  NE2 . GLN E 1 201 ? -6.548  -16.548 24.175  1.00 23.53  ? 201 GLN E NE2 1 
ATOM   10674 N  N   . GLU E 1 202 ? -10.347 -11.337 26.370  1.00 27.08  ? 202 GLU E N   1 
ATOM   10675 C  CA  . GLU E 1 202 ? -10.383 -9.995  26.949  1.00 27.56  ? 202 GLU E CA  1 
ATOM   10676 C  C   . GLU E 1 202 ? -11.405 -9.958  28.070  1.00 26.90  ? 202 GLU E C   1 
ATOM   10677 O  O   . GLU E 1 202 ? -11.246 -9.208  29.023  1.00 25.86  ? 202 GLU E O   1 
ATOM   10678 C  CB  . GLU E 1 202 ? -10.667 -8.934  25.896  1.00 27.66  ? 202 GLU E CB  1 
ATOM   10679 C  CG  . GLU E 1 202 ? -9.468  -8.715  24.979  1.00 30.18  ? 202 GLU E CG  1 
ATOM   10680 C  CD  . GLU E 1 202 ? -9.738  -7.930  23.709  1.00 32.66  ? 202 GLU E CD  1 
ATOM   10681 O  OE1 . GLU E 1 202 ? -10.923 -7.785  23.373  1.00 32.94  ? 202 GLU E OE1 1 
ATOM   10682 O  OE2 . GLU E 1 202 ? -8.755  -7.433  23.122  1.00 31.03  ? 202 GLU E OE2 1 
ATOM   10683 N  N   . ARG E 1 203 ? -12.436 -10.776 27.921  1.00 30.09  ? 203 ARG E N   1 
ATOM   10684 C  CA  . ARG E 1 203 ? -13.539 -10.809 28.868  1.00 42.31  ? 203 ARG E CA  1 
ATOM   10685 C  C   . ARG E 1 203 ? -13.098 -11.521 30.149  1.00 34.63  ? 203 ARG E C   1 
ATOM   10686 O  O   . ARG E 1 203 ? -13.575 -11.183 31.216  1.00 39.29  ? 203 ARG E O   1 
ATOM   10687 C  CB  . ARG E 1 203 ? -14.807 -11.419 28.234  1.00 50.76  ? 203 ARG E CB  1 
ATOM   10688 C  CG  . ARG E 1 203 ? -15.595 -10.402 27.404  1.00 55.81  ? 203 ARG E CG  1 
ATOM   10689 C  CD  . ARG E 1 203 ? -16.637 -10.986 26.387  1.00 71.65  ? 203 ARG E CD  1 
ATOM   10690 N  NE  . ARG E 1 203 ? -17.353 -9.884  25.714  1.00 89.59  ? 203 ARG E NE  1 
ATOM   10691 C  CZ  . ARG E 1 203 ? -16.825 -8.843  25.005  1.00 89.74  ? 203 ARG E CZ  1 
ATOM   10692 N  NH1 . ARG E 1 203 ? -17.479 -7.698  24.881  1.00 84.93  ? 203 ARG E NH1 1 
ATOM   10693 N  NH2 . ARG E 1 203 ? -15.607 -8.894  24.497  1.00 84.29  ? 203 ARG E NH2 1 
ATOM   10694 N  N   . VAL E 1 204 ? -12.229 -12.518 30.044  1.00 27.33  ? 204 VAL E N   1 
ATOM   10695 C  CA  . VAL E 1 204 ? -11.660 -13.178 31.215  1.00 26.52  ? 204 VAL E CA  1 
ATOM   10696 C  C   . VAL E 1 204 ? -10.730 -12.233 32.003  1.00 25.98  ? 204 VAL E C   1 
ATOM   10697 O  O   . VAL E 1 204 ? -10.713 -12.210 33.234  1.00 29.06  ? 204 VAL E O   1 
ATOM   10698 C  CB  . VAL E 1 204 ? -10.911 -14.439 30.773  1.00 25.69  ? 204 VAL E CB  1 
ATOM   10699 C  CG1 . VAL E 1 204 ? -10.108 -15.079 31.891  1.00 27.69  ? 204 VAL E CG1 1 
ATOM   10700 C  CG2 . VAL E 1 204 ? -11.834 -15.455 30.145  1.00 29.35  ? 204 VAL E CG2 1 
ATOM   10701 N  N   . ILE E 1 205 ? -9.922  -11.443 31.300  1.00 27.87  ? 205 ILE E N   1 
ATOM   10702 C  CA  . ILE E 1 205 ? -8.931  -10.602 31.943  1.00 30.37  ? 205 ILE E CA  1 
ATOM   10703 C  C   . ILE E 1 205 ? -9.591  -9.323  32.436  1.00 25.48  ? 205 ILE E C   1 
ATOM   10704 O  O   . ILE E 1 205 ? -9.439  -8.944  33.585  1.00 24.31  ? 205 ILE E O   1 
ATOM   10705 C  CB  . ILE E 1 205 ? -7.718  -10.334 31.020  1.00 26.23  ? 205 ILE E CB  1 
ATOM   10706 C  CG1 . ILE E 1 205 ? -7.038  -11.635 30.634  1.00 23.71  ? 205 ILE E CG1 1 
ATOM   10707 C  CG2 . ILE E 1 205 ? -6.746  -9.382  31.726  1.00 27.14  ? 205 ILE E CG2 1 
ATOM   10708 C  CD1 . ILE E 1 205 ? -6.461  -12.394 31.810  1.00 25.48  ? 205 ILE E CD1 1 
ATOM   10709 N  N   . GLY E 1 206 ? -10.246 -8.629  31.519  1.00 28.07  ? 206 GLY E N   1 
ATOM   10710 C  CA  . GLY E 1 206 ? -10.815 -7.340  31.821  1.00 26.36  ? 206 GLY E CA  1 
ATOM   10711 C  C   . GLY E 1 206 ? -10.101 -6.220  31.095  1.00 26.94  ? 206 GLY E C   1 
ATOM   10712 O  O   . GLY E 1 206 ? -10.430 -5.064  31.349  1.00 31.97  ? 206 GLY E O   1 
ATOM   10713 N  N   . ARG E 1 207 ? -9.135  -6.528  30.223  1.00 26.25  ? 207 ARG E N   1 
ATOM   10714 C  CA  . ARG E 1 207 ? -8.434  -5.486  29.471  1.00 28.23  ? 207 ARG E CA  1 
ATOM   10715 C  C   . ARG E 1 207 ? -8.272  -5.941  28.029  1.00 26.71  ? 207 ARG E C   1 
ATOM   10716 O  O   . ARG E 1 207 ? -8.410  -7.126  27.762  1.00 26.03  ? 207 ARG E O   1 
ATOM   10717 C  CB  . ARG E 1 207 ? -7.036  -5.178  29.992  1.00 30.34  ? 207 ARG E CB  1 
ATOM   10718 C  CG  . ARG E 1 207 ? -6.952  -4.989  31.499  1.00 35.12  ? 207 ARG E CG  1 
ATOM   10719 C  CD  . ARG E 1 207 ? -5.490  -4.767  32.040  1.00 31.49  ? 207 ARG E CD  1 
ATOM   10720 N  NE  . ARG E 1 207 ? -5.001  -3.452  31.611  1.00 28.31  ? 207 ARG E NE  1 
ATOM   10721 C  CZ  . ARG E 1 207 ? -5.266  -2.235  32.142  1.00 30.16  ? 207 ARG E CZ  1 
ATOM   10722 N  NH1 . ARG E 1 207 ? -5.872  -2.055  33.315  1.00 31.06  ? 207 ARG E NH1 1 
ATOM   10723 N  NH2 . ARG E 1 207 ? -4.850  -1.141  31.509  1.00 27.67  ? 207 ARG E NH2 1 
ATOM   10724 N  N   . ARG E 1 208 ? -8.026  -4.984  27.125  1.00 26.99  ? 208 ARG E N   1 
ATOM   10725 C  CA  . ARG E 1 208 ? -7.796  -5.268  25.714  1.00 30.11  ? 208 ARG E CA  1 
ATOM   10726 C  C   . ARG E 1 208 ? -6.437  -5.959  25.543  1.00 29.79  ? 208 ARG E C   1 
ATOM   10727 O  O   . ARG E 1 208 ? -5.468  -5.581  26.191  1.00 29.65  ? 208 ARG E O   1 
ATOM   10728 C  CB  . ARG E 1 208 ? -7.856  -4.015  24.818  1.00 35.07  ? 208 ARG E CB  1 
ATOM   10729 C  CG  . ARG E 1 208 ? -9.155  -3.215  24.867  1.00 41.54  ? 208 ARG E CG  1 
ATOM   10730 C  CD  . ARG E 1 208 ? -10.432 -4.068  24.693  1.00 57.20  ? 208 ARG E CD  1 
ATOM   10731 N  NE  . ARG E 1 208 ? -10.467 -4.621  23.335  1.00 69.37  ? 208 ARG E NE  1 
ATOM   10732 C  CZ  . ARG E 1 208 ? -10.635 -3.872  22.241  1.00 71.36  ? 208 ARG E CZ  1 
ATOM   10733 N  NH1 . ARG E 1 208 ? -11.062 -2.632  22.351  1.00 79.76  ? 208 ARG E NH1 1 
ATOM   10734 N  NH2 . ARG E 1 208 ? -10.414 -4.356  21.035  1.00 55.83  ? 208 ARG E NH2 1 
ATOM   10735 N  N   . LYS E 1 209 ? -6.341  -6.933  24.629  1.00 26.73  ? 209 LYS E N   1 
ATOM   10736 C  CA  . LYS E 1 209 ? -5.137  -7.728  24.565  1.00 26.66  ? 209 LYS E CA  1 
ATOM   10737 C  C   . LYS E 1 209 ? -4.001  -6.953  23.886  1.00 28.00  ? 209 LYS E C   1 
ATOM   10738 O  O   . LYS E 1 209 ? -2.961  -6.820  24.483  1.00 28.92  ? 209 LYS E O   1 
ATOM   10739 C  CB  . LYS E 1 209 ? -5.421  -9.053  23.859  1.00 26.56  ? 209 LYS E CB  1 
ATOM   10740 C  CG  . LYS E 1 209 ? -4.236  -9.982  23.903  1.00 24.40  ? 209 LYS E CG  1 
ATOM   10741 C  CD  . LYS E 1 209 ? -4.571  -11.339 23.347  1.00 27.42  ? 209 LYS E CD  1 
ATOM   10742 C  CE  . LYS E 1 209 ? -3.512  -12.321 23.778  1.00 29.94  ? 209 LYS E CE  1 
ATOM   10743 N  NZ  . LYS E 1 209 ? -3.808  -13.648 23.259  1.00 29.52  ? 209 LYS E NZ  1 
ATOM   10744 N  N   . MET E 1 210 ? -4.259  -6.396  22.693  1.00 30.39  ? 210 MET E N   1 
ATOM   10745 C  CA  . MET E 1 210 ? -3.299  -5.693  21.865  1.00 35.42  ? 210 MET E CA  1 
ATOM   10746 C  C   . MET E 1 210 ? -2.929  -4.361  22.554  1.00 33.55  ? 210 MET E C   1 
ATOM   10747 O  O   . MET E 1 210 ? -1.766  -4.101  22.787  1.00 33.31  ? 210 MET E O   1 
ATOM   10748 C  CB  . MET E 1 210 ? -3.866  -5.525  20.438  1.00 40.42  ? 210 MET E CB  1 
ATOM   10749 C  CG  . MET E 1 210 ? -3.101  -4.513  19.500  1.00 68.46  ? 210 MET E CG  1 
ATOM   10750 S  SD  . MET E 1 210 ? -1.875  -5.077  18.267  1.00 87.80  ? 210 MET E SD  1 
ATOM   10751 C  CE  . MET E 1 210 ? -0.716  -6.049  19.256  1.00 84.73  ? 210 MET E CE  1 
ATOM   10752 N  N   . THR E 1 211 ? -3.895  -3.534  22.970  1.00 27.89  ? 211 THR E N   1 
ATOM   10753 C  CA  . THR E 1 211 ? -3.625  -2.150  23.349  1.00 30.53  ? 211 THR E CA  1 
ATOM   10754 C  C   . THR E 1 211 ? -3.520  -1.982  24.867  1.00 29.46  ? 211 THR E C   1 
ATOM   10755 O  O   . THR E 1 211 ? -3.167  -0.899  25.320  1.00 28.59  ? 211 THR E O   1 
ATOM   10756 C  CB  . THR E 1 211 ? -4.719  -1.218  22.798  1.00 28.74  ? 211 THR E CB  1 
ATOM   10757 O  OG1 . THR E 1 211 ? -5.939  -1.644  23.391  1.00 32.93  ? 211 THR E OG1 1 
ATOM   10758 C  CG2 . THR E 1 211 ? -4.903  -1.355  21.301  1.00 29.66  ? 211 THR E CG2 1 
ATOM   10759 N  N   . ASP E 1 212 ? -3.901  -3.001  25.655  1.00 29.01  ? 212 ASP E N   1 
ATOM   10760 C  CA  . ASP E 1 212 ? -3.824  -2.938  27.121  1.00 28.64  ? 212 ASP E CA  1 
ATOM   10761 C  C   . ASP E 1 212 ? -4.715  -1.865  27.742  1.00 24.93  ? 212 ASP E C   1 
ATOM   10762 O  O   . ASP E 1 212 ? -4.481  -1.458  28.871  1.00 26.44  ? 212 ASP E O   1 
ATOM   10763 C  CB  . ASP E 1 212 ? -2.436  -2.694  27.701  1.00 25.76  ? 212 ASP E CB  1 
ATOM   10764 C  CG  . ASP E 1 212 ? -2.184  -3.206  29.111  1.00 29.38  ? 212 ASP E CG  1 
ATOM   10765 O  OD1 . ASP E 1 212 ? -2.999  -4.092  29.662  1.00 31.43  ? 212 ASP E OD1 1 
ATOM   10766 O  OD2 . ASP E 1 212 ? -1.157  -2.706  29.626  1.00 35.17  ? 212 ASP E OD2 1 
ATOM   10767 N  N   . VAL E 1 213 ? -5.741  -1.424  27.034  1.00 26.19  ? 213 VAL E N   1 
ATOM   10768 C  CA  . VAL E 1 213 ? -6.690  -0.476  27.603  1.00 28.18  ? 213 VAL E CA  1 
ATOM   10769 C  C   . VAL E 1 213 ? -7.753  -1.235  28.401  1.00 25.55  ? 213 VAL E C   1 
ATOM   10770 O  O   . VAL E 1 213 ? -8.301  -2.247  27.993  1.00 25.00  ? 213 VAL E O   1 
ATOM   10771 C  CB  . VAL E 1 213 ? -7.316  0.313   26.441  1.00 32.10  ? 213 VAL E CB  1 
ATOM   10772 C  CG1 . VAL E 1 213 ? -8.459  1.180   26.917  1.00 34.20  ? 213 VAL E CG1 1 
ATOM   10773 C  CG2 . VAL E 1 213 ? -6.274  1.142   25.702  1.00 34.22  ? 213 VAL E CG2 1 
ATOM   10774 N  N   . GLU E 1 214 ? -8.073  -0.734  29.581  1.00 33.61  ? 214 GLU E N   1 
ATOM   10775 C  CA  . GLU E 1 214 ? -9.040  -1.421  30.435  1.00 34.77  ? 214 GLU E CA  1 
ATOM   10776 C  C   . GLU E 1 214 ? -10.406 -1.397  29.795  1.00 30.61  ? 214 GLU E C   1 
ATOM   10777 O  O   . GLU E 1 214 ? -10.727 -0.366  29.277  1.00 40.06  ? 214 GLU E O   1 
ATOM   10778 C  CB  . GLU E 1 214 ? -9.082  -0.633  31.732  1.00 36.30  ? 214 GLU E CB  1 
ATOM   10779 C  CG  . GLU E 1 214 ? -9.716  -1.473  32.827  1.00 43.10  ? 214 GLU E CG  1 
ATOM   10780 C  CD  . GLU E 1 214 ? -9.741  -0.749  34.159  1.00 38.31  ? 214 GLU E CD  1 
ATOM   10781 O  OE1 . GLU E 1 214 ? -9.493  0.483   34.335  1.00 49.41  ? 214 GLU E OE1 1 
ATOM   10782 O  OE2 . GLU E 1 214 ? -10.216 -1.504  35.017  1.00 39.35  ? 214 GLU E OE2 1 
ATOM   10783 N  N   . LEU E 1 215 ? -11.168 -2.492  29.797  1.00 32.62  ? 215 LEU E N   1 
ATOM   10784 C  CA  . LEU E 1 215 ? -12.552 -2.518  29.300  1.00 31.42  ? 215 LEU E CA  1 
ATOM   10785 C  C   . LEU E 1 215 ? -13.362 -1.614  30.187  1.00 32.82  ? 215 LEU E C   1 
ATOM   10786 O  O   . LEU E 1 215 ? -13.107 -1.610  31.372  1.00 33.18  ? 215 LEU E O   1 
ATOM   10787 C  CB  . LEU E 1 215 ? -13.173 -3.907  29.441  1.00 30.64  ? 215 LEU E CB  1 
ATOM   10788 C  CG  . LEU E 1 215 ? -12.605 -5.012  28.552  1.00 31.38  ? 215 LEU E CG  1 
ATOM   10789 C  CD1 . LEU E 1 215 ? -13.383 -6.331  28.732  1.00 29.99  ? 215 LEU E CD1 1 
ATOM   10790 C  CD2 . LEU E 1 215 ? -12.634 -4.522  27.145  1.00 33.33  ? 215 LEU E CD2 1 
ATOM   10791 N  N   . SER E 1 216 ? -14.331 -0.870  29.652  1.00 43.26  ? 216 SER E N   1 
ATOM   10792 C  CA  . SER E 1 216 ? -15.086 0.055   30.504  1.00 48.52  ? 216 SER E CA  1 
ATOM   10793 C  C   . SER E 1 216 ? -15.983 -0.701  31.506  1.00 63.57  ? 216 SER E C   1 
ATOM   10794 O  O   . SER E 1 216 ? -16.366 -1.860  31.276  1.00 56.66  ? 216 SER E O   1 
ATOM   10795 C  CB  . SER E 1 216 ? -15.901 0.992   29.681  1.00 47.05  ? 216 SER E CB  1 
ATOM   10796 O  OG  . SER E 1 216 ? -16.864 0.229   28.971  1.00 46.68  ? 216 SER E OG  1 
ATOM   10797 N  N   . ASP E 1 217 ? -16.319 -0.009  32.615  1.00 69.89  ? 217 ASP E N   1 
ATOM   10798 C  CA  . ASP E 1 217 ? -17.159 -0.510  33.704  1.00 68.24  ? 217 ASP E CA  1 
ATOM   10799 C  C   . ASP E 1 217 ? -18.463 -1.156  33.207  1.00 54.92  ? 217 ASP E C   1 
ATOM   10800 O  O   . ASP E 1 217 ? -18.821 -2.220  33.707  1.00 44.62  ? 217 ASP E O   1 
ATOM   10801 C  CB  . ASP E 1 217 ? -17.385 0.631   34.692  1.00 67.52  ? 217 ASP E CB  1 
ATOM   10802 C  CG  . ASP E 1 217 ? -16.116 1.071   35.384  1.00 67.50  ? 217 ASP E CG  1 
ATOM   10803 O  OD1 . ASP E 1 217 ? -15.509 0.176   35.991  1.00 67.36  ? 217 ASP E OD1 1 
ATOM   10804 O  OD2 . ASP E 1 217 ? -15.753 2.271   35.298  1.00 85.94  ? 217 ASP E OD2 1 
ATOM   10805 N  N   . ASP E 1 218 ? -19.136 -0.491  32.236  1.00 60.11  ? 218 ASP E N   1 
ATOM   10806 C  CA  . ASP E 1 218 ? -20.395 -0.923  31.631  1.00 60.53  ? 218 ASP E CA  1 
ATOM   10807 C  C   . ASP E 1 218 ? -20.154 -2.283  30.945  1.00 58.00  ? 218 ASP E C   1 
ATOM   10808 O  O   . ASP E 1 218 ? -21.069 -3.086  30.938  1.00 51.50  ? 218 ASP E O   1 
ATOM   10809 C  CB  . ASP E 1 218 ? -21.148 0.211   30.891  1.00 47.29  ? 218 ASP E CB  1 
ATOM   10810 N  N   . VAL E 1 219 ? -18.937 -2.661  30.478  1.00 57.76  ? 219 VAL E N   1 
ATOM   10811 C  CA  . VAL E 1 219 ? -18.807 -3.921  29.733  1.00 56.67  ? 219 VAL E CA  1 
ATOM   10812 C  C   . VAL E 1 219 ? -17.925 -5.007  30.395  1.00 50.44  ? 219 VAL E C   1 
ATOM   10813 O  O   . VAL E 1 219 ? -17.865 -6.173  29.991  1.00 46.26  ? 219 VAL E O   1 
ATOM   10814 C  CB  . VAL E 1 219 ? -18.421 -3.685  28.257  1.00 53.40  ? 219 VAL E CB  1 
ATOM   10815 C  CG1 . VAL E 1 219 ? -18.162 -2.233  27.843  1.00 52.45  ? 219 VAL E CG1 1 
ATOM   10816 C  CG2 . VAL E 1 219 ? -17.309 -4.631  27.825  1.00 50.62  ? 219 VAL E CG2 1 
ATOM   10817 N  N   . LYS E 1 220 ? -17.210 -4.672  31.442  1.00 46.17  ? 220 LYS E N   1 
ATOM   10818 C  CA  . LYS E 1 220 ? -16.291 -5.651  31.999  1.00 43.12  ? 220 LYS E CA  1 
ATOM   10819 C  C   . LYS E 1 220 ? -17.064 -6.618  32.884  1.00 36.07  ? 220 LYS E C   1 
ATOM   10820 O  O   . LYS E 1 220 ? -17.617 -6.232  33.898  1.00 33.73  ? 220 LYS E O   1 
ATOM   10821 C  CB  . LYS E 1 220 ? -15.247 -4.886  32.822  1.00 44.27  ? 220 LYS E CB  1 
ATOM   10822 C  CG  . LYS E 1 220 ? -14.220 -5.686  33.580  1.00 41.74  ? 220 LYS E CG  1 
ATOM   10823 C  CD  . LYS E 1 220 ? -13.548 -4.834  34.649  1.00 42.05  ? 220 LYS E CD  1 
ATOM   10824 C  CE  . LYS E 1 220 ? -13.125 -3.544  34.052  1.00 48.95  ? 220 LYS E CE  1 
ATOM   10825 N  NZ  . LYS E 1 220 ? -12.608 -2.616  35.055  1.00 57.18  ? 220 LYS E NZ  1 
ATOM   10826 N  N   . PRO E 1 221 ? -17.064 -7.920  32.595  1.00 35.01  ? 221 PRO E N   1 
ATOM   10827 C  CA  . PRO E 1 221 ? -17.762 -8.896  33.435  1.00 33.87  ? 221 PRO E CA  1 
ATOM   10828 C  C   . PRO E 1 221 ? -17.300 -8.873  34.883  1.00 37.57  ? 221 PRO E C   1 
ATOM   10829 O  O   . PRO E 1 221 ? -16.148 -8.583  35.177  1.00 39.04  ? 221 PRO E O   1 
ATOM   10830 C  CB  . PRO E 1 221 ? -17.476 -10.266 32.827  1.00 33.05  ? 221 PRO E CB  1 
ATOM   10831 C  CG  . PRO E 1 221 ? -16.853 -10.003 31.457  1.00 32.09  ? 221 PRO E CG  1 
ATOM   10832 C  CD  . PRO E 1 221 ? -16.377 -8.551  31.471  1.00 35.91  ? 221 PRO E CD  1 
ATOM   10833 N  N   . ALA E 1 222 ? -18.222 -9.240  35.781  1.00 35.01  ? 222 ALA E N   1 
ATOM   10834 C  CA  . ALA E 1 222 ? -17.980 -9.276  37.206  1.00 33.45  ? 222 ALA E CA  1 
ATOM   10835 C  C   . ALA E 1 222 ? -17.057 -10.461 37.569  1.00 35.94  ? 222 ALA E C   1 
ATOM   10836 O  O   . ALA E 1 222 ? -16.403 -10.419 38.606  1.00 45.46  ? 222 ALA E O   1 
ATOM   10837 C  CB  . ALA E 1 222 ? -19.299 -9.342  37.929  1.00 30.67  ? 222 ALA E CB  1 
ATOM   10838 N  N   . ASP E 1 223 ? -16.960 -11.504 36.732  1.00 31.33  ? 223 ASP E N   1 
ATOM   10839 C  CA  . ASP E 1 223 ? -16.052 -12.585 37.020  1.00 31.92  ? 223 ASP E CA  1 
ATOM   10840 C  C   . ASP E 1 223 ? -14.738 -12.448 36.224  1.00 35.28  ? 223 ASP E C   1 
ATOM   10841 O  O   . ASP E 1 223 ? -13.969 -13.431 36.099  1.00 31.77  ? 223 ASP E O   1 
ATOM   10842 C  CB  . ASP E 1 223 ? -16.735 -13.926 36.821  1.00 30.58  ? 223 ASP E CB  1 
ATOM   10843 C  CG  . ASP E 1 223 ? -17.204 -14.197 35.412  1.00 30.93  ? 223 ASP E CG  1 
ATOM   10844 O  OD1 . ASP E 1 223 ? -17.219 -13.254 34.660  1.00 30.21  ? 223 ASP E OD1 1 
ATOM   10845 O  OD2 . ASP E 1 223 ? -17.452 -15.357 35.061  1.00 35.77  ? 223 ASP E OD2 1 
ATOM   10846 N  N   . SER E 1 224 ? -14.470 -11.232 35.703  1.00 35.93  ? 224 SER E N   1 
ATOM   10847 C  CA  . SER E 1 224 ? -13.166 -10.940 35.105  1.00 34.05  ? 224 SER E CA  1 
ATOM   10848 C  C   . SER E 1 224 ? -12.136 -10.721 36.212  1.00 33.82  ? 224 SER E C   1 
ATOM   10849 O  O   . SER E 1 224 ? -12.486 -10.274 37.325  1.00 31.31  ? 224 SER E O   1 
ATOM   10850 C  CB  . SER E 1 224 ? -13.193 -9.782  34.142  1.00 29.59  ? 224 SER E CB  1 
ATOM   10851 O  OG  . SER E 1 224 ? -13.277 -8.607  34.895  1.00 27.25  ? 224 SER E OG  1 
ATOM   10852 N  N   . HIS E 1 225 ? -10.863 -11.046 35.883  1.00 34.45  ? 225 HIS E N   1 
ATOM   10853 C  CA  . HIS E 1 225 ? -9.771  -10.984 36.853  1.00 27.99  ? 225 HIS E CA  1 
ATOM   10854 C  C   . HIS E 1 225 ? -9.615  -9.584  37.460  1.00 26.07  ? 225 HIS E C   1 
ATOM   10855 O  O   . HIS E 1 225 ? -9.448  -9.409  38.653  1.00 26.16  ? 225 HIS E O   1 
ATOM   10856 C  CB  . HIS E 1 225 ? -8.529  -11.548 36.172  1.00 30.35  ? 225 HIS E CB  1 
ATOM   10857 C  CG  . HIS E 1 225 ? -7.325  -11.475 37.059  1.00 33.05  ? 225 HIS E CG  1 
ATOM   10858 N  ND1 . HIS E 1 225 ? -7.273  -12.224 38.195  1.00 30.96  ? 225 HIS E ND1 1 
ATOM   10859 C  CD2 . HIS E 1 225 ? -6.137  -10.827 36.953  1.00 29.14  ? 225 HIS E CD2 1 
ATOM   10860 C  CE1 . HIS E 1 225 ? -6.119  -11.957 38.772  1.00 37.53  ? 225 HIS E CE1 1 
ATOM   10861 N  NE2 . HIS E 1 225 ? -5.428  -11.119 38.033  1.00 31.71  ? 225 HIS E NE2 1 
ATOM   10862 N  N   . VAL E 1 226 ? -9.671  -8.568  36.600  1.00 29.97  ? 226 VAL E N   1 
ATOM   10863 C  CA  . VAL E 1 226 ? -9.493  -7.191  37.022  1.00 32.64  ? 226 VAL E CA  1 
ATOM   10864 C  C   . VAL E 1 226 ? -10.652 -6.748  37.917  1.00 30.59  ? 226 VAL E C   1 
ATOM   10865 O  O   . VAL E 1 226 ? -10.454 -5.922  38.820  1.00 27.98  ? 226 VAL E O   1 
ATOM   10866 C  CB  . VAL E 1 226 ? -9.328  -6.265  35.794  1.00 36.18  ? 226 VAL E CB  1 
ATOM   10867 C  CG1 . VAL E 1 226 ? -9.589  -4.804  36.136  1.00 34.00  ? 226 VAL E CG1 1 
ATOM   10868 C  CG2 . VAL E 1 226 ? -7.922  -6.378  35.231  1.00 36.92  ? 226 VAL E CG2 1 
ATOM   10869 N  N   . ALA E 1 227 ? -11.857 -7.252  37.642  1.00 29.02  ? 227 ALA E N   1 
ATOM   10870 C  CA  . ALA E 1 227 ? -13.017 -6.873  38.445  1.00 28.74  ? 227 ALA E CA  1 
ATOM   10871 C  C   . ALA E 1 227 ? -12.831 -7.434  39.846  1.00 28.78  ? 227 ALA E C   1 
ATOM   10872 O  O   . ALA E 1 227 ? -12.933 -6.708  40.817  1.00 31.77  ? 227 ALA E O   1 
ATOM   10873 C  CB  . ALA E 1 227 ? -14.295 -7.443  37.879  1.00 30.28  ? 227 ALA E CB  1 
ATOM   10874 N  N   . LEU E 1 228 ? -12.544 -8.725  39.939  1.00 28.60  ? 228 LEU E N   1 
ATOM   10875 C  CA  . LEU E 1 228 ? -12.389 -9.383  41.221  1.00 31.14  ? 228 LEU E CA  1 
ATOM   10876 C  C   . LEU E 1 228 ? -11.160 -8.912  42.021  1.00 37.56  ? 228 LEU E C   1 
ATOM   10877 O  O   . LEU E 1 228 ? -11.190 -9.033  43.242  1.00 41.37  ? 228 LEU E O   1 
ATOM   10878 C  CB  . LEU E 1 228 ? -12.344 -10.891 41.017  1.00 29.33  ? 228 LEU E CB  1 
ATOM   10879 C  CG  . LEU E 1 228 ? -13.666 -11.516 40.637  1.00 37.70  ? 228 LEU E CG  1 
ATOM   10880 C  CD1 . LEU E 1 228 ? -13.474 -12.973 40.174  1.00 41.54  ? 228 LEU E CD1 1 
ATOM   10881 C  CD2 . LEU E 1 228 ? -14.572 -11.392 41.877  1.00 39.38  ? 228 LEU E CD2 1 
ATOM   10882 N  N   . THR E 1 229 ? -10.059 -8.456  41.388  1.00 33.60  ? 229 THR E N   1 
ATOM   10883 C  CA  . THR E 1 229 ? -8.905  -8.097  42.178  1.00 32.88  ? 229 THR E CA  1 
ATOM   10884 C  C   . THR E 1 229 ? -8.895  -6.605  42.440  1.00 35.10  ? 229 THR E C   1 
ATOM   10885 O  O   . THR E 1 229 ? -7.909  -6.149  43.007  1.00 37.89  ? 229 THR E O   1 
ATOM   10886 C  CB  . THR E 1 229 ? -7.618  -8.586  41.534  1.00 34.20  ? 229 THR E CB  1 
ATOM   10887 O  OG1 . THR E 1 229 ? -7.666  -8.080  40.221  1.00 30.73  ? 229 THR E OG1 1 
ATOM   10888 C  CG2 . THR E 1 229 ? -7.547  -10.101 41.444  1.00 38.12  ? 229 THR E CG2 1 
ATOM   10889 N  N   . SER E 1 230 ? -9.960  -5.872  42.055  1.00 40.91  ? 230 SER E N   1 
ATOM   10890 C  CA  . SER E 1 230 ? -10.175 -4.493  42.527  1.00 50.59  ? 230 SER E CA  1 
ATOM   10891 C  C   . SER E 1 230 ? -11.081 -4.484  43.767  1.00 43.93  ? 230 SER E C   1 
ATOM   10892 O  O   . SER E 1 230 ? -12.277 -4.774  43.713  1.00 42.17  ? 230 SER E O   1 
ATOM   10893 C  CB  . SER E 1 230 ? -10.738 -3.570  41.461  1.00 50.06  ? 230 SER E CB  1 
ATOM   10894 O  OG  . SER E 1 230 ? -9.971  -3.642  40.258  1.00 58.13  ? 230 SER E OG  1 
ATOM   10895 N  N   . VAL E 1 231 ? -10.505 -4.079  44.890  1.00 40.47  ? 231 VAL E N   1 
ATOM   10896 C  CA  . VAL E 1 231 ? -11.172 -4.038  46.173  1.00 48.52  ? 231 VAL E CA  1 
ATOM   10897 C  C   . VAL E 1 231 ? -10.965 -2.632  46.726  1.00 54.53  ? 231 VAL E C   1 
ATOM   10898 O  O   . VAL E 1 231 ? -9.838  -2.092  46.652  1.00 41.70  ? 231 VAL E O   1 
ATOM   10899 C  CB  . VAL E 1 231 ? -10.566 -5.059  47.149  1.00 64.26  ? 231 VAL E CB  1 
ATOM   10900 C  CG1 . VAL E 1 231 ? -11.518 -5.249  48.334  1.00 81.36  ? 231 VAL E CG1 1 
ATOM   10901 C  CG2 . VAL E 1 231 ? -10.181 -6.383  46.488  1.00 57.53  ? 231 VAL E CG2 1 
ATOM   10902 N  N   . THR E 1 232 ? -12.050 -2.020  47.245  1.00 53.73  ? 232 THR E N   1 
ATOM   10903 C  CA  . THR E 1 232 ? -11.883 -0.752  47.956  1.00 60.50  ? 232 THR E CA  1 
ATOM   10904 C  C   . THR E 1 232 ? -11.906 -1.038  49.464  1.00 61.26  ? 232 THR E C   1 
ATOM   10905 O  O   . THR E 1 232 ? -12.466 -2.034  49.899  1.00 57.28  ? 232 THR E O   1 
ATOM   10906 C  CB  . THR E 1 232 ? -12.910 0.272   47.494  1.00 56.97  ? 232 THR E CB  1 
ATOM   10907 O  OG1 . THR E 1 232 ? -13.998 -0.458  48.027  1.00 53.91  ? 232 THR E OG1 1 
ATOM   10908 C  CG2 . THR E 1 232 ? -13.045 0.406   45.987  1.00 55.36  ? 232 THR E CG2 1 
ATOM   10909 N  N   . GLY E 1 233 ? -11.131 -0.285  50.248  1.00 77.65  ? 233 GLY E N   1 
ATOM   10910 C  CA  . GLY E 1 233 ? -11.130 -0.522  51.677  1.00 84.94  ? 233 GLY E CA  1 
ATOM   10911 C  C   . GLY E 1 233 ? -12.255 0.290   52.298  1.00 104.03 ? 233 GLY E C   1 
ATOM   10912 O  O   . GLY E 1 233 ? -12.826 1.170   51.642  1.00 87.48  ? 233 GLY E O   1 
ATOM   10913 N  N   . PRO E 1 234 ? -12.573 0.067   53.595  1.00 118.00 ? 234 PRO E N   1 
ATOM   10914 C  CA  . PRO E 1 234 ? -13.169 1.153   54.387  1.00 113.30 ? 234 PRO E CA  1 
ATOM   10915 C  C   . PRO E 1 234 ? -12.725 2.594   54.024  1.00 115.69 ? 234 PRO E C   1 
ATOM   10916 O  O   . PRO E 1 234 ? -13.607 3.421   53.754  1.00 80.55  ? 234 PRO E O   1 
ATOM   10917 C  CB  . PRO E 1 234 ? -12.769 0.650   55.792  1.00 124.89 ? 234 PRO E CB  1 
ATOM   10918 C  CG  . PRO E 1 234 ? -12.944 -0.888  55.697  1.00 120.22 ? 234 PRO E CG  1 
ATOM   10919 C  CD  . PRO E 1 234 ? -12.404 -1.218  54.315  1.00 106.46 ? 234 PRO E CD  1 
ATOM   10920 N  N   . ASP E 1 235 ? -11.401 2.890   53.874  1.00 128.95 ? 235 ASP E N   1 
ATOM   10921 C  CA  . ASP E 1 235 ? -10.926 4.234   53.467  1.00 110.97 ? 235 ASP E CA  1 
ATOM   10922 C  C   . ASP E 1 235 ? -11.768 4.856   52.331  1.00 115.80 ? 235 ASP E C   1 
ATOM   10923 O  O   . ASP E 1 235 ? -11.775 6.072   52.217  1.00 74.29  ? 235 ASP E O   1 
ATOM   10924 C  CB  . ASP E 1 235 ? -9.439  4.376   53.091  1.00 67.52  ? 235 ASP E CB  1 
ATOM   10925 N  N   . GLY E 1 236 ? -12.445 4.075   51.449  1.00 123.56 ? 236 GLY E N   1 
ATOM   10926 C  CA  . GLY E 1 236 ? -12.906 4.572   50.149  1.00 94.59  ? 236 GLY E CA  1 
ATOM   10927 C  C   . GLY E 1 236 ? -11.860 4.354   49.039  1.00 92.11  ? 236 GLY E C   1 
ATOM   10928 O  O   . GLY E 1 236 ? -12.220 3.965   47.924  1.00 65.28  ? 236 GLY E O   1 
ATOM   10929 N  N   . SER E 1 237 ? -10.558 4.588   49.363  1.00 112.78 ? 237 SER E N   1 
ATOM   10930 C  CA  . SER E 1 237 ? -9.428  4.358   48.466  1.00 90.12  ? 237 SER E CA  1 
ATOM   10931 C  C   . SER E 1 237 ? -9.327  2.860   48.155  1.00 81.27  ? 237 SER E C   1 
ATOM   10932 O  O   . SER E 1 237 ? -9.792  1.955   48.882  1.00 66.89  ? 237 SER E O   1 
ATOM   10933 C  CB  . SER E 1 237 ? -8.074  4.920   48.991  1.00 65.41  ? 237 SER E CB  1 
ATOM   10934 N  N   . ASP E 1 238 ? -8.701  2.611   47.007  1.00 70.92  ? 238 ASP E N   1 
ATOM   10935 C  CA  . ASP E 1 238 ? -8.407  1.256   46.543  1.00 70.38  ? 238 ASP E CA  1 
ATOM   10936 C  C   . ASP E 1 238 ? -7.337  0.620   47.424  1.00 54.64  ? 238 ASP E C   1 
ATOM   10937 O  O   . ASP E 1 238 ? -6.436  1.281   47.927  1.00 52.15  ? 238 ASP E O   1 
ATOM   10938 C  CB  . ASP E 1 238 ? -7.994  1.263   45.078  1.00 64.77  ? 238 ASP E CB  1 
ATOM   10939 C  CG  . ASP E 1 238 ? -8.993  2.014   44.201  1.00 71.52  ? 238 ASP E CG  1 
ATOM   10940 O  OD1 . ASP E 1 238 ? -10.173 1.599   44.146  1.00 65.11  ? 238 ASP E OD1 1 
ATOM   10941 O  OD2 . ASP E 1 238 ? -8.611  3.059   43.641  1.00 89.06  ? 238 ASP E OD2 1 
ATOM   10942 N  N   . LEU E 1 239 ? -7.444  -0.685  47.606  1.00 42.50  ? 239 LEU E N   1 
ATOM   10943 C  CA  . LEU E 1 239 ? -6.394  -1.457  48.226  1.00 46.43  ? 239 LEU E CA  1 
ATOM   10944 C  C   . LEU E 1 239 ? -5.442  -2.007  47.169  1.00 40.62  ? 239 LEU E C   1 
ATOM   10945 O  O   . LEU E 1 239 ? -5.868  -2.731  46.281  1.00 42.19  ? 239 LEU E O   1 
ATOM   10946 C  CB  . LEU E 1 239 ? -7.083  -2.595  48.974  1.00 60.32  ? 239 LEU E CB  1 
ATOM   10947 C  CG  . LEU E 1 239 ? -7.831  -2.145  50.231  1.00 58.35  ? 239 LEU E CG  1 
ATOM   10948 C  CD1 . LEU E 1 239 ? -8.386  -3.430  50.851  1.00 60.99  ? 239 LEU E CD1 1 
ATOM   10949 C  CD2 . LEU E 1 239 ? -7.005  -1.282  51.222  1.00 43.85  ? 239 LEU E CD2 1 
ATOM   10950 N  N   . GLU E 1 240 ? -4.149  -1.712  47.295  1.00 36.67  ? 240 GLU E N   1 
ATOM   10951 C  CA  . GLU E 1 240 ? -3.216  -2.086  46.252  1.00 37.82  ? 240 GLU E CA  1 
ATOM   10952 C  C   . GLU E 1 240 ? -2.176  -3.102  46.715  1.00 34.93  ? 240 GLU E C   1 
ATOM   10953 O  O   . GLU E 1 240 ? -1.750  -3.058  47.857  1.00 31.44  ? 240 GLU E O   1 
ATOM   10954 C  CB  . GLU E 1 240 ? -2.563  -0.797  45.787  1.00 41.83  ? 240 GLU E CB  1 
ATOM   10955 C  CG  . GLU E 1 240 ? -3.569  0.307   45.496  1.00 39.24  ? 240 GLU E CG  1 
ATOM   10956 C  CD  . GLU E 1 240 ? -2.895  1.223   44.547  1.00 44.01  ? 240 GLU E CD  1 
ATOM   10957 O  OE1 . GLU E 1 240 ? -2.282  2.180   45.018  1.00 51.32  ? 240 GLU E OE1 1 
ATOM   10958 O  OE2 . GLU E 1 240 ? -2.894  0.829   43.385  1.00 46.35  ? 240 GLU E OE2 1 
ATOM   10959 N  N   . ILE E 1 241 ? -1.751  -3.983  45.788  1.00 33.72  ? 241 ILE E N   1 
ATOM   10960 C  CA  . ILE E 1 241 ? -0.533  -4.765  45.972  1.00 32.58  ? 241 ILE E CA  1 
ATOM   10961 C  C   . ILE E 1 241 ? 0.496   -4.475  44.864  1.00 31.58  ? 241 ILE E C   1 
ATOM   10962 O  O   . ILE E 1 241 ? 0.186   -3.855  43.841  1.00 28.11  ? 241 ILE E O   1 
ATOM   10963 C  CB  . ILE E 1 241 ? -0.837  -6.264  46.091  1.00 32.22  ? 241 ILE E CB  1 
ATOM   10964 C  CG1 . ILE E 1 241 ? -1.345  -6.830  44.809  1.00 29.69  ? 241 ILE E CG1 1 
ATOM   10965 C  CG2 . ILE E 1 241 ? -1.845  -6.498  47.218  1.00 40.14  ? 241 ILE E CG2 1 
ATOM   10966 C  CD1 . ILE E 1 241 ? -1.578  -8.330  44.832  1.00 28.54  ? 241 ILE E CD1 1 
ATOM   10967 N  N   . LEU E 1 242 ? 1.734   -4.912  45.125  1.00 27.20  ? 242 LEU E N   1 
ATOM   10968 C  CA  . LEU E 1 242 ? 2.806   -4.854  44.152  1.00 26.92  ? 242 LEU E CA  1 
ATOM   10969 C  C   . LEU E 1 242 ? 3.155   -6.258  43.692  1.00 23.53  ? 242 LEU E C   1 
ATOM   10970 O  O   . LEU E 1 242 ? 3.572   -7.039  44.501  1.00 21.00  ? 242 LEU E O   1 
ATOM   10971 C  CB  . LEU E 1 242 ? 4.032   -4.188  44.737  1.00 29.70  ? 242 LEU E CB  1 
ATOM   10972 C  CG  . LEU E 1 242 ? 5.155   -3.939  43.724  1.00 33.06  ? 242 LEU E CG  1 
ATOM   10973 C  CD1 . LEU E 1 242 ? 4.696   -2.786  42.874  1.00 35.05  ? 242 LEU E CD1 1 
ATOM   10974 C  CD2 . LEU E 1 242 ? 6.503   -3.571  44.322  1.00 31.13  ? 242 LEU E CD2 1 
ATOM   10975 N  N   . ARG E 1 243 ? 2.960   -6.538  42.413  1.00 22.54  ? 243 ARG E N   1 
ATOM   10976 C  CA  . ARG E 1 243 ? 3.144   -7.869  41.864  1.00 24.68  ? 243 ARG E CA  1 
ATOM   10977 C  C   . ARG E 1 243 ? 4.327   -7.896  40.911  1.00 23.46  ? 243 ARG E C   1 
ATOM   10978 O  O   . ARG E 1 243 ? 4.687   -6.874  40.390  1.00 24.54  ? 243 ARG E O   1 
ATOM   10979 C  CB  . ARG E 1 243 ? 1.973   -8.220  40.962  1.00 26.26  ? 243 ARG E CB  1 
ATOM   10980 C  CG  . ARG E 1 243 ? 0.706   -8.366  41.768  1.00 28.18  ? 243 ARG E CG  1 
ATOM   10981 C  CD  . ARG E 1 243 ? -0.455  -8.419  40.813  1.00 26.96  ? 243 ARG E CD  1 
ATOM   10982 N  NE  . ARG E 1 243 ? -0.686  -7.088  40.221  1.00 27.22  ? 243 ARG E NE  1 
ATOM   10983 C  CZ  . ARG E 1 243 ? -0.735  -6.771  38.928  1.00 26.06  ? 243 ARG E CZ  1 
ATOM   10984 N  NH1 . ARG E 1 243 ? -0.671  -7.739  37.990  1.00 25.79  ? 243 ARG E NH1 1 
ATOM   10985 N  NH2 . ARG E 1 243 ? -0.929  -5.493  38.594  1.00 26.33  ? 243 ARG E NH2 1 
ATOM   10986 N  N   . ASP E 1 244 ? 4.964   -9.042  40.742  1.00 23.22  ? 244 ASP E N   1 
ATOM   10987 C  CA  . ASP E 1 244 ? 6.032   -9.185  39.775  1.00 27.89  ? 244 ASP E CA  1 
ATOM   10988 C  C   . ASP E 1 244 ? 5.973   -10.584 39.156  1.00 26.28  ? 244 ASP E C   1 
ATOM   10989 O  O   . ASP E 1 244 ? 6.948   -11.317 39.213  1.00 28.61  ? 244 ASP E O   1 
ATOM   10990 C  CB  . ASP E 1 244 ? 7.379   -8.724  40.327  1.00 31.31  ? 244 ASP E CB  1 
ATOM   10991 C  CG  . ASP E 1 244 ? 8.392   -8.314  39.262  1.00 32.91  ? 244 ASP E CG  1 
ATOM   10992 O  OD1 . ASP E 1 244 ? 8.006   -8.319  38.089  1.00 33.83  ? 244 ASP E OD1 1 
ATOM   10993 O  OD2 . ASP E 1 244 ? 9.549   -8.055  39.583  1.00 29.31  ? 244 ASP E OD2 1 
ATOM   10994 N  N   . ASN E 1 245 ? 4.837   -10.893 38.524  1.00 20.65  ? 245 ASN E N   1 
ATOM   10995 C  CA  . ASN E 1 245 ? 4.594   -12.204 38.011  1.00 22.57  ? 245 ASN E CA  1 
ATOM   10996 C  C   . ASN E 1 245 ? 5.578   -12.512 36.893  1.00 23.43  ? 245 ASN E C   1 
ATOM   10997 O  O   . ASN E 1 245 ? 5.862   -11.657 36.053  1.00 22.71  ? 245 ASN E O   1 
ATOM   10998 C  CB  . ASN E 1 245 ? 3.190   -12.278 37.428  1.00 29.88  ? 245 ASN E CB  1 
ATOM   10999 C  CG  . ASN E 1 245 ? 2.113   -11.967 38.432  1.00 30.09  ? 245 ASN E CG  1 
ATOM   11000 O  OD1 . ASN E 1 245 ? 2.417   -11.993 39.633  1.00 29.75  ? 245 ASN E OD1 1 
ATOM   11001 N  ND2 . ASN E 1 245 ? 0.902   -11.680 37.930  1.00 29.53  ? 245 ASN E ND2 1 
ATOM   11002 N  N   . MET E 1 246 ? 6.009   -13.765 36.810  1.00 21.07  ? 246 MET E N   1 
ATOM   11003 C  CA  . MET E 1 246 ? 7.006   -14.153 35.841  1.00 23.36  ? 246 MET E CA  1 
ATOM   11004 C  C   . MET E 1 246 ? 6.587   -15.433 35.176  1.00 23.86  ? 246 MET E C   1 
ATOM   11005 O  O   . MET E 1 246 ? 6.361   -16.434 35.837  1.00 27.85  ? 246 MET E O   1 
ATOM   11006 C  CB  . MET E 1 246 ? 8.360   -14.490 36.494  1.00 29.17  ? 246 MET E CB  1 
ATOM   11007 C  CG  . MET E 1 246 ? 9.101   -13.279 37.083  1.00 31.89  ? 246 MET E CG  1 
ATOM   11008 S  SD  . MET E 1 246 ? 9.487   -11.992 35.879  1.00 30.38  ? 246 MET E SD  1 
ATOM   11009 C  CE  . MET E 1 246 ? 10.867  -12.854 35.137  1.00 33.54  ? 246 MET E CE  1 
ATOM   11010 N  N   . PRO E 1 247 ? 6.594   -15.482 33.844  1.00 23.05  ? 247 PRO E N   1 
ATOM   11011 C  CA  . PRO E 1 247 ? 6.457   -16.737 33.122  1.00 20.79  ? 247 PRO E CA  1 
ATOM   11012 C  C   . PRO E 1 247 ? 7.588   -17.703 33.406  1.00 20.97  ? 247 PRO E C   1 
ATOM   11013 O  O   . PRO E 1 247 ? 8.725   -17.334 33.640  1.00 18.18  ? 247 PRO E O   1 
ATOM   11014 C  CB  . PRO E 1 247 ? 6.549   -16.287 31.671  1.00 23.32  ? 247 PRO E CB  1 
ATOM   11015 C  CG  . PRO E 1 247 ? 6.230   -14.804 31.700  1.00 24.46  ? 247 PRO E CG  1 
ATOM   11016 C  CD  . PRO E 1 247 ? 6.714   -14.302 32.999  1.00 25.97  ? 247 PRO E CD  1 
ATOM   11017 N  N   . PHE E 1 248 ? 7.294   -18.982 33.231  1.00 22.91  ? 248 PHE E N   1 
ATOM   11018 C  CA  . PHE E 1 248 ? 8.324   -20.001 33.246  1.00 21.75  ? 248 PHE E CA  1 
ATOM   11019 C  C   . PHE E 1 248 ? 7.761   -21.192 32.494  1.00 23.44  ? 248 PHE E C   1 
ATOM   11020 O  O   . PHE E 1 248 ? 6.581   -21.274 32.242  1.00 24.26  ? 248 PHE E O   1 
ATOM   11021 C  CB  . PHE E 1 248 ? 8.665   -20.395 34.686  1.00 23.19  ? 248 PHE E CB  1 
ATOM   11022 C  CG  . PHE E 1 248 ? 7.533   -21.157 35.372  1.00 23.01  ? 248 PHE E CG  1 
ATOM   11023 C  CD1 . PHE E 1 248 ? 6.518   -20.463 36.014  1.00 21.20  ? 248 PHE E CD1 1 
ATOM   11024 C  CD2 . PHE E 1 248 ? 7.499   -22.542 35.382  1.00 20.07  ? 248 PHE E CD2 1 
ATOM   11025 C  CE1 . PHE E 1 248 ? 5.532   -21.151 36.680  1.00 21.41  ? 248 PHE E CE1 1 
ATOM   11026 C  CE2 . PHE E 1 248 ? 6.506   -23.223 36.027  1.00 18.95  ? 248 PHE E CE2 1 
ATOM   11027 C  CZ  . PHE E 1 248 ? 5.523   -22.532 36.666  1.00 20.40  ? 248 PHE E CZ  1 
ATOM   11028 N  N   . GLY E 1 249 ? 8.615   -22.126 32.134  1.00 22.66  ? 249 GLY E N   1 
ATOM   11029 C  CA  . GLY E 1 249 ? 8.082   -23.369 31.670  1.00 21.77  ? 249 GLY E CA  1 
ATOM   11030 C  C   . GLY E 1 249 ? 9.159   -24.302 31.156  1.00 25.26  ? 249 GLY E C   1 
ATOM   11031 O  O   . GLY E 1 249 ? 10.354  -24.022 31.193  1.00 24.73  ? 249 GLY E O   1 
ATOM   11032 N  N   . SER E 1 250 ? 8.671   -25.355 30.516  1.00 27.80  ? 250 SER E N   1 
ATOM   11033 C  CA  . SER E 1 250 ? 9.481   -26.338 29.845  1.00 29.42  ? 250 SER E CA  1 
ATOM   11034 C  C   . SER E 1 250 ? 8.695   -26.910 28.663  1.00 29.26  ? 250 SER E C   1 
ATOM   11035 O  O   . SER E 1 250 ? 7.563   -27.332 28.793  1.00 30.08  ? 250 SER E O   1 
ATOM   11036 C  CB  . SER E 1 250 ? 9.881   -27.368 30.840  1.00 30.50  ? 250 SER E CB  1 
ATOM   11037 O  OG  . SER E 1 250 ? 10.008  -28.609 30.169  1.00 34.08  ? 250 SER E OG  1 
ATOM   11038 N  N   . VAL E 1 251 ? 9.224   -26.810 27.455  1.00 31.97  ? 251 VAL E N   1 
ATOM   11039 C  CA  . VAL E 1 251 ? 8.422   -27.158 26.283  1.00 42.32  ? 251 VAL E CA  1 
ATOM   11040 C  C   . VAL E 1 251 ? 8.321   -28.675 26.153  1.00 37.32  ? 251 VAL E C   1 
ATOM   11041 O  O   . VAL E 1 251 ? 7.299   -29.180 25.730  1.00 39.99  ? 251 VAL E O   1 
ATOM   11042 C  CB  . VAL E 1 251 ? 8.884   -26.545 24.941  1.00 45.57  ? 251 VAL E CB  1 
ATOM   11043 C  CG1 . VAL E 1 251 ? 8.515   -25.074 24.914  1.00 48.40  ? 251 VAL E CG1 1 
ATOM   11044 C  CG2 . VAL E 1 251 ? 10.375  -26.749 24.681  1.00 47.10  ? 251 VAL E CG2 1 
ATOM   11045 N  N   . GLY E 1 252 ? 9.383   -29.395 26.508  1.00 35.10  ? 252 GLY E N   1 
ATOM   11046 C  CA  . GLY E 1 252 ? 9.368   -30.845 26.422  1.00 34.56  ? 252 GLY E CA  1 
ATOM   11047 C  C   . GLY E 1 252 ? 8.320   -31.465 27.348  1.00 35.15  ? 252 GLY E C   1 
ATOM   11048 O  O   . GLY E 1 252 ? 7.660   -32.405 26.965  1.00 36.93  ? 252 GLY E O   1 
ATOM   11049 N  N   . ARG E 1 253 ? 8.163   -30.943 28.561  1.00 38.06  ? 253 ARG E N   1 
ATOM   11050 C  CA  . ARG E 1 253 ? 7.153   -31.416 29.491  1.00 37.35  ? 253 ARG E CA  1 
ATOM   11051 C  C   . ARG E 1 253 ? 5.805   -30.730 29.312  1.00 36.11  ? 253 ARG E C   1 
ATOM   11052 O  O   . ARG E 1 253 ? 4.928   -30.925 30.094  1.00 43.53  ? 253 ARG E O   1 
ATOM   11053 C  CB  . ARG E 1 253 ? 7.645   -31.118 30.909  1.00 47.06  ? 253 ARG E CB  1 
ATOM   11054 C  CG  . ARG E 1 253 ? 8.876   -31.950 31.279  1.00 62.85  ? 253 ARG E CG  1 
ATOM   11055 C  CD  . ARG E 1 253 ? 8.868   -32.410 32.752  1.00 70.69  ? 253 ARG E CD  1 
ATOM   11056 N  NE  . ARG E 1 253 ? 8.566   -31.233 33.573  1.00 85.04  ? 253 ARG E NE  1 
ATOM   11057 C  CZ  . ARG E 1 253 ? 9.317   -30.133 33.526  1.00 88.93  ? 253 ARG E CZ  1 
ATOM   11058 N  NH1 . ARG E 1 253 ? 10.552  -30.186 33.035  1.00 73.47  ? 253 ARG E NH1 1 
ATOM   11059 N  NH2 . ARG E 1 253 ? 8.845   -28.998 34.007  1.00 106.90 ? 253 ARG E NH2 1 
ATOM   11060 N  N   . GLU E 1 254 ? 5.592   -29.902 28.308  1.00 42.49  ? 254 GLU E N   1 
ATOM   11061 C  CA  . GLU E 1 254 ? 4.358   -29.138 28.213  1.00 43.15  ? 254 GLU E CA  1 
ATOM   11062 C  C   . GLU E 1 254 ? 3.965   -28.367 29.478  1.00 39.90  ? 254 GLU E C   1 
ATOM   11063 O  O   . GLU E 1 254 ? 2.797   -28.223 29.751  1.00 39.25  ? 254 GLU E O   1 
ATOM   11064 C  CB  . GLU E 1 254 ? 3.210   -30.070 27.867  1.00 48.98  ? 254 GLU E CB  1 
ATOM   11065 C  CG  . GLU E 1 254 ? 3.189   -30.520 26.419  1.00 66.99  ? 254 GLU E CG  1 
ATOM   11066 C  CD  . GLU E 1 254 ? 1.812   -31.090 26.064  1.00 81.72  ? 254 GLU E CD  1 
ATOM   11067 O  OE1 . GLU E 1 254 ? 0.814   -30.309 26.072  1.00 82.49  ? 254 GLU E OE1 1 
ATOM   11068 O  OE2 . GLU E 1 254 ? 1.747   -32.318 25.804  1.00 88.82  ? 254 GLU E OE2 1 
ATOM   11069 N  N   . GLU E 1 255 ? 4.890   -27.729 30.200  1.00 38.00  ? 255 GLU E N   1 
ATOM   11070 C  CA  . GLU E 1 255 ? 4.556   -26.914 31.350  1.00 34.49  ? 255 GLU E CA  1 
ATOM   11071 C  C   . GLU E 1 255 ? 4.675   -25.454 30.929  1.00 33.75  ? 255 GLU E C   1 
ATOM   11072 O  O   . GLU E 1 255 ? 5.734   -25.006 30.474  1.00 36.68  ? 255 GLU E O   1 
ATOM   11073 C  CB  . GLU E 1 255 ? 5.565   -27.123 32.473  1.00 41.47  ? 255 GLU E CB  1 
ATOM   11074 C  CG  . GLU E 1 255 ? 5.497   -28.497 33.121  1.00 54.03  ? 255 GLU E CG  1 
ATOM   11075 C  CD  . GLU E 1 255 ? 6.081   -28.490 34.528  1.00 66.90  ? 255 GLU E CD  1 
ATOM   11076 O  OE1 . GLU E 1 255 ? 5.675   -29.407 35.285  1.00 67.42  ? 255 GLU E OE1 1 
ATOM   11077 O  OE2 . GLU E 1 255 ? 6.931   -27.591 34.862  1.00 51.37  ? 255 GLU E OE2 1 
ATOM   11078 N  N   . PHE E 1 256 ? 3.590   -24.705 31.071  1.00 29.77  ? 256 PHE E N   1 
ATOM   11079 C  CA  . PHE E 1 256 ? 3.597   -23.286 30.776  1.00 27.45  ? 256 PHE E CA  1 
ATOM   11080 C  C   . PHE E 1 256 ? 3.005   -22.620 32.011  1.00 25.61  ? 256 PHE E C   1 
ATOM   11081 O  O   . PHE E 1 256 ? 1.932   -22.951 32.392  1.00 26.92  ? 256 PHE E O   1 
ATOM   11082 C  CB  . PHE E 1 256 ? 2.820   -22.908 29.503  1.00 28.63  ? 256 PHE E CB  1 
ATOM   11083 C  CG  . PHE E 1 256 ? 3.273   -23.731 28.323  1.00 30.85  ? 256 PHE E CG  1 
ATOM   11084 C  CD1 . PHE E 1 256 ? 4.322   -23.278 27.543  1.00 40.21  ? 256 PHE E CD1 1 
ATOM   11085 C  CD2 . PHE E 1 256 ? 2.700   -24.957 28.009  1.00 30.99  ? 256 PHE E CD2 1 
ATOM   11086 C  CE1 . PHE E 1 256 ? 4.833   -24.048 26.485  1.00 37.98  ? 256 PHE E CE1 1 
ATOM   11087 C  CE2 . PHE E 1 256 ? 3.230   -25.719 26.964  1.00 37.15  ? 256 PHE E CE2 1 
ATOM   11088 C  CZ  . PHE E 1 256 ? 4.326   -25.280 26.226  1.00 37.09  ? 256 PHE E CZ  1 
ATOM   11089 N  N   . GLY E 1 257 ? 3.690   -21.677 32.630  1.00 24.12  ? 257 GLY E N   1 
ATOM   11090 C  CA  . GLY E 1 257 ? 3.330   -21.248 33.960  1.00 24.80  ? 257 GLY E CA  1 
ATOM   11091 C  C   . GLY E 1 257 ? 3.468   -19.736 34.180  1.00 21.74  ? 257 GLY E C   1 
ATOM   11092 O  O   . GLY E 1 257 ? 4.014   -19.022 33.366  1.00 20.79  ? 257 GLY E O   1 
ATOM   11093 N  N   . THR E 1 258 ? 2.850   -19.292 35.269  1.00 20.30  ? 258 THR E N   1 
ATOM   11094 C  CA  . THR E 1 258 ? 2.973   -17.979 35.816  1.00 23.17  ? 258 THR E CA  1 
ATOM   11095 C  C   . THR E 1 258 ? 3.373   -18.161 37.275  1.00 25.68  ? 258 THR E C   1 
ATOM   11096 O  O   . THR E 1 258 ? 2.672   -18.828 38.018  1.00 23.41  ? 258 THR E O   1 
ATOM   11097 C  CB  . THR E 1 258 ? 1.680   -17.188 35.709  1.00 21.32  ? 258 THR E CB  1 
ATOM   11098 O  OG1 . THR E 1 258 ? 1.396   -16.984 34.325  1.00 23.46  ? 258 THR E OG1 1 
ATOM   11099 C  CG2 . THR E 1 258 ? 1.928   -15.826 36.350  1.00 22.45  ? 258 THR E CG2 1 
ATOM   11100 N  N   . TYR E 1 259 ? 4.493   -17.544 37.676  1.00 23.57  ? 259 TYR E N   1 
ATOM   11101 C  CA  . TYR E 1 259 ? 4.900   -17.522 39.061  1.00 22.70  ? 259 TYR E CA  1 
ATOM   11102 C  C   . TYR E 1 259 ? 4.368   -16.216 39.617  1.00 23.37  ? 259 TYR E C   1 
ATOM   11103 O  O   . TYR E 1 259 ? 4.805   -15.172 39.221  1.00 23.05  ? 259 TYR E O   1 
ATOM   11104 C  CB  . TYR E 1 259 ? 6.405   -17.698 39.294  1.00 24.90  ? 259 TYR E CB  1 
ATOM   11105 C  CG  . TYR E 1 259 ? 6.740   -18.187 40.698  1.00 22.50  ? 259 TYR E CG  1 
ATOM   11106 C  CD1 . TYR E 1 259 ? 6.857   -17.277 41.716  1.00 24.99  ? 259 TYR E CD1 1 
ATOM   11107 C  CD2 . TYR E 1 259 ? 6.896   -19.524 40.980  1.00 20.31  ? 259 TYR E CD2 1 
ATOM   11108 C  CE1 . TYR E 1 259 ? 7.124   -17.697 43.003  1.00 28.66  ? 259 TYR E CE1 1 
ATOM   11109 C  CE2 . TYR E 1 259 ? 7.163   -19.981 42.241  1.00 23.75  ? 259 TYR E CE2 1 
ATOM   11110 C  CZ  . TYR E 1 259 ? 7.266   -19.058 43.274  1.00 30.42  ? 259 TYR E CZ  1 
ATOM   11111 O  OH  . TYR E 1 259 ? 7.567   -19.466 44.557  1.00 29.13  ? 259 TYR E OH  1 
ATOM   11112 N  N   . PHE E 1 260 ? 3.333   -16.283 40.462  1.00 23.78  ? 260 PHE E N   1 
ATOM   11113 C  CA  . PHE E 1 260 ? 2.767   -15.108 41.083  1.00 19.45  ? 260 PHE E CA  1 
ATOM   11114 C  C   . PHE E 1 260 ? 3.543   -14.786 42.347  1.00 20.38  ? 260 PHE E C   1 
ATOM   11115 O  O   . PHE E 1 260 ? 3.772   -15.642 43.200  1.00 19.98  ? 260 PHE E O   1 
ATOM   11116 C  CB  . PHE E 1 260 ? 1.326   -15.403 41.475  1.00 21.07  ? 260 PHE E CB  1 
ATOM   11117 C  CG  . PHE E 1 260 ? 0.725   -14.310 42.337  1.00 21.05  ? 260 PHE E CG  1 
ATOM   11118 C  CD1 . PHE E 1 260 ? 0.313   -13.122 41.796  1.00 22.25  ? 260 PHE E CD1 1 
ATOM   11119 C  CD2 . PHE E 1 260 ? 0.653   -14.442 43.702  1.00 24.16  ? 260 PHE E CD2 1 
ATOM   11120 C  CE1 . PHE E 1 260 ? -0.132  -12.070 42.585  1.00 23.42  ? 260 PHE E CE1 1 
ATOM   11121 C  CE2 . PHE E 1 260 ? 0.159   -13.411 44.474  1.00 23.70  ? 260 PHE E CE2 1 
ATOM   11122 C  CZ  . PHE E 1 260 ? -0.217  -12.237 43.917  1.00 23.15  ? 260 PHE E CZ  1 
ATOM   11123 N  N   . ILE E 1 261 ? 3.909   -13.518 42.473  1.00 21.69  ? 261 ILE E N   1 
ATOM   11124 C  CA  . ILE E 1 261 ? 4.373   -13.001 43.753  1.00 24.21  ? 261 ILE E CA  1 
ATOM   11125 C  C   . ILE E 1 261 ? 3.769   -11.611 43.972  1.00 23.85  ? 261 ILE E C   1 
ATOM   11126 O  O   . ILE E 1 261 ? 3.763   -10.754 43.096  1.00 24.96  ? 261 ILE E O   1 
ATOM   11127 C  CB  . ILE E 1 261 ? 5.913   -12.986 43.866  1.00 24.37  ? 261 ILE E CB  1 
ATOM   11128 C  CG1 . ILE E 1 261 ? 6.346   -12.551 45.255  1.00 26.57  ? 261 ILE E CG1 1 
ATOM   11129 C  CG2 . ILE E 1 261 ? 6.546   -12.125 42.761  1.00 26.87  ? 261 ILE E CG2 1 
ATOM   11130 C  CD1 . ILE E 1 261 ? 7.793   -12.809 45.540  1.00 26.24  ? 261 ILE E CD1 1 
ATOM   11131 N  N   . GLY E 1 262 ? 3.180   -11.427 45.137  1.00 22.64  ? 262 GLY E N   1 
ATOM   11132 C  CA  . GLY E 1 262 ? 2.498   -10.198 45.511  1.00 25.99  ? 262 GLY E CA  1 
ATOM   11133 C  C   . GLY E 1 262 ? 2.970   -9.702  46.875  1.00 24.35  ? 262 GLY E C   1 
ATOM   11134 O  O   . GLY E 1 262 ? 3.058   -10.464 47.842  1.00 24.39  ? 262 GLY E O   1 
ATOM   11135 N  N   . TYR E 1 263 ? 3.334   -8.430  46.914  1.00 23.07  ? 263 TYR E N   1 
ATOM   11136 C  CA  . TYR E 1 263 ? 3.855   -7.837  48.134  1.00 24.02  ? 263 TYR E CA  1 
ATOM   11137 C  C   . TYR E 1 263 ? 2.843   -6.811  48.622  1.00 25.87  ? 263 TYR E C   1 
ATOM   11138 O  O   . TYR E 1 263 ? 2.258   -6.061  47.814  1.00 26.46  ? 263 TYR E O   1 
ATOM   11139 C  CB  . TYR E 1 263 ? 5.172   -7.088  47.889  1.00 26.43  ? 263 TYR E CB  1 
ATOM   11140 C  CG  . TYR E 1 263 ? 6.399   -7.945  47.633  1.00 24.09  ? 263 TYR E CG  1 
ATOM   11141 C  CD1 . TYR E 1 263 ? 7.186   -8.348  48.665  1.00 24.55  ? 263 TYR E CD1 1 
ATOM   11142 C  CD2 . TYR E 1 263 ? 6.777   -8.307  46.359  1.00 26.33  ? 263 TYR E CD2 1 
ATOM   11143 C  CE1 . TYR E 1 263 ? 8.326   -9.079  48.440  1.00 26.88  ? 263 TYR E CE1 1 
ATOM   11144 C  CE2 . TYR E 1 263 ? 7.947   -8.997  46.105  1.00 25.36  ? 263 TYR E CE2 1 
ATOM   11145 C  CZ  . TYR E 1 263 ? 8.714   -9.405  47.159  1.00 26.42  ? 263 TYR E CZ  1 
ATOM   11146 O  OH  . TYR E 1 263 ? 9.861   -10.112 46.989  1.00 26.54  ? 263 TYR E OH  1 
ATOM   11147 N  N   . ALA E 1 264 ? 2.632   -6.780  49.941  1.00 26.58  ? 264 ALA E N   1 
ATOM   11148 C  CA  . ALA E 1 264 ? 1.731   -5.815  50.566  1.00 28.75  ? 264 ALA E CA  1 
ATOM   11149 C  C   . ALA E 1 264 ? 2.143   -5.532  52.005  1.00 26.06  ? 264 ALA E C   1 
ATOM   11150 O  O   . ALA E 1 264 ? 2.802   -6.383  52.620  1.00 27.50  ? 264 ALA E O   1 
ATOM   11151 C  CB  . ALA E 1 264 ? 0.324   -6.397  50.484  1.00 34.17  ? 264 ALA E CB  1 
ATOM   11152 N  N   . ARG E 1 265 ? 1.709   -4.381  52.550  1.00 29.20  ? 265 ARG E N   1 
ATOM   11153 C  CA  . ARG E 1 265 ? 2.068   -3.938  53.906  1.00 31.95  ? 265 ARG E CA  1 
ATOM   11154 C  C   . ARG E 1 265 ? 1.380   -4.797  54.966  1.00 28.61  ? 265 ARG E C   1 
ATOM   11155 O  O   . ARG E 1 265 ? 1.876   -4.897  56.086  1.00 29.00  ? 265 ARG E O   1 
ATOM   11156 C  CB  . ARG E 1 265 ? 1.844   -2.447  54.231  1.00 36.00  ? 265 ARG E CB  1 
ATOM   11157 C  CG  . ARG E 1 265 ? 0.373   -2.082  54.410  1.00 46.89  ? 265 ARG E CG  1 
ATOM   11158 C  CD  . ARG E 1 265 ? 0.063   -0.578  54.621  1.00 55.46  ? 265 ARG E CD  1 
ATOM   11159 N  NE  . ARG E 1 265 ? 0.851   -0.037  55.745  1.00 57.42  ? 265 ARG E NE  1 
ATOM   11160 C  CZ  . ARG E 1 265 ? 1.449   1.160   55.929  1.00 52.83  ? 265 ARG E CZ  1 
ATOM   11161 N  NH1 . ARG E 1 265 ? 1.808   1.564   57.124  1.00 50.33  ? 265 ARG E NH1 1 
ATOM   11162 N  NH2 . ARG E 1 265 ? 1.649   2.000   54.950  1.00 58.86  ? 265 ARG E NH2 1 
ATOM   11163 N  N   . THR E 1 266 ? 0.288   -5.474  54.598  1.00 32.36  ? 266 THR E N   1 
ATOM   11164 C  CA  . THR E 1 266 ? -0.353  -6.457  55.466  1.00 32.27  ? 266 THR E CA  1 
ATOM   11165 C  C   . THR E 1 266 ? -0.900  -7.580  54.592  1.00 29.24  ? 266 THR E C   1 
ATOM   11166 O  O   . THR E 1 266 ? -1.412  -7.324  53.508  1.00 27.61  ? 266 THR E O   1 
ATOM   11167 C  CB  . THR E 1 266 ? -1.482  -5.813  56.283  1.00 32.76  ? 266 THR E CB  1 
ATOM   11168 O  OG1 . THR E 1 266 ? -2.319  -6.839  56.823  1.00 37.68  ? 266 THR E OG1 1 
ATOM   11169 C  CG2 . THR E 1 266 ? -2.393  -4.986  55.385  1.00 33.21  ? 266 THR E CG2 1 
ATOM   11170 N  N   . PRO E 1 267 ? -0.871  -8.867  55.027  1.00 28.63  ? 267 PRO E N   1 
ATOM   11171 C  CA  . PRO E 1 267 ? -1.426  -9.944  54.218  1.00 28.83  ? 267 PRO E CA  1 
ATOM   11172 C  C   . PRO E 1 267 ? -2.932  -9.864  54.017  1.00 31.38  ? 267 PRO E C   1 
ATOM   11173 O  O   . PRO E 1 267 ? -3.393  -10.515 53.077  1.00 31.77  ? 267 PRO E O   1 
ATOM   11174 C  CB  . PRO E 1 267 ? -1.001  -11.214 54.891  1.00 31.54  ? 267 PRO E CB  1 
ATOM   11175 C  CG  . PRO E 1 267 ? -0.572  -10.796 56.260  1.00 32.52  ? 267 PRO E CG  1 
ATOM   11176 C  CD  . PRO E 1 267 ? -0.254  -9.358  56.248  1.00 30.59  ? 267 PRO E CD  1 
ATOM   11177 N  N   . GLU E 1 268 ? -3.669  -9.095  54.873  1.00 32.76  ? 268 GLU E N   1 
ATOM   11178 C  CA  . GLU E 1 268 ? -5.132  -9.017  54.791  1.00 31.22  ? 268 GLU E CA  1 
ATOM   11179 C  C   . GLU E 1 268 ? -5.468  -8.553  53.341  1.00 36.81  ? 268 GLU E C   1 
ATOM   11180 O  O   . GLU E 1 268 ? -6.416  -9.040  52.705  1.00 30.96  ? 268 GLU E O   1 
ATOM   11181 C  CB  . GLU E 1 268 ? -5.773  -8.150  55.896  1.00 31.83  ? 268 GLU E CB  1 
ATOM   11182 C  CG  . GLU E 1 268 ? -5.628  -8.604  57.358  1.00 34.19  ? 268 GLU E CG  1 
ATOM   11183 N  N   . VAL E 1 269 ? -4.664  -7.640  52.734  1.00 31.49  ? 269 VAL E N   1 
ATOM   11184 C  CA  . VAL E 1 269 ? -4.975  -7.176  51.394  1.00 31.27  ? 269 VAL E CA  1 
ATOM   11185 C  C   . VAL E 1 269 ? -4.909  -8.339  50.387  1.00 30.81  ? 269 VAL E C   1 
ATOM   11186 O  O   . VAL E 1 269 ? -5.874  -8.628  49.622  1.00 32.65  ? 269 VAL E O   1 
ATOM   11187 C  CB  . VAL E 1 269 ? -4.107  -5.967  51.000  1.00 31.80  ? 269 VAL E CB  1 
ATOM   11188 C  CG1 . VAL E 1 269 ? -4.460  -5.413  49.640  1.00 32.44  ? 269 VAL E CG1 1 
ATOM   11189 C  CG2 . VAL E 1 269 ? -4.308  -4.813  51.961  1.00 33.49  ? 269 VAL E CG2 1 
ATOM   11190 N  N   . THR E 1 270 ? -3.763  -9.019  50.396  1.00 25.80  ? 270 THR E N   1 
ATOM   11191 C  CA  . THR E 1 270 ? -3.542  -10.096 49.452  1.00 25.72  ? 270 THR E CA  1 
ATOM   11192 C  C   . THR E 1 270 ? -4.562  -11.219 49.660  1.00 28.60  ? 270 THR E C   1 
ATOM   11193 O  O   . THR E 1 270 ? -5.064  -11.862 48.690  1.00 29.30  ? 270 THR E O   1 
ATOM   11194 C  CB  . THR E 1 270 ? -2.111  -10.592 49.586  1.00 24.26  ? 270 THR E CB  1 
ATOM   11195 O  OG1 . THR E 1 270 ? -1.278  -9.457  49.415  1.00 25.87  ? 270 THR E OG1 1 
ATOM   11196 C  CG2 . THR E 1 270 ? -1.804  -11.515 48.439  1.00 27.19  ? 270 THR E CG2 1 
ATOM   11197 N  N   . GLU E 1 271 ? -4.873  -11.505 50.948  1.00 34.46  ? 271 GLU E N   1 
ATOM   11198 C  CA  . GLU E 1 271 ? -5.763  -12.627 51.303  1.00 28.86  ? 271 GLU E CA  1 
ATOM   11199 C  C   . GLU E 1 271 ? -7.190  -12.315 50.851  1.00 25.60  ? 271 GLU E C   1 
ATOM   11200 O  O   . GLU E 1 271 ? -7.897  -13.211 50.401  1.00 30.44  ? 271 GLU E O   1 
ATOM   11201 C  CB  . GLU E 1 271 ? -5.697  -12.926 52.798  1.00 25.82  ? 271 GLU E CB  1 
ATOM   11202 C  CG  . GLU E 1 271 ? -4.456  -13.742 53.147  1.00 29.66  ? 271 GLU E CG  1 
ATOM   11203 C  CD  . GLU E 1 271 ? -4.059  -13.817 54.602  1.00 31.11  ? 271 GLU E CD  1 
ATOM   11204 O  OE1 . GLU E 1 271 ? -4.649  -13.079 55.422  1.00 33.74  ? 271 GLU E OE1 1 
ATOM   11205 O  OE2 . GLU E 1 271 ? -3.176  -14.679 54.884  1.00 36.36  ? 271 GLU E OE2 1 
ATOM   11206 N  N   . THR E 1 272 ? -7.588  -11.040 50.898  1.00 25.74  ? 272 THR E N   1 
ATOM   11207 C  CA  . THR E 1 272 ? -8.907  -10.693 50.421  1.00 26.93  ? 272 THR E CA  1 
ATOM   11208 C  C   . THR E 1 272 ? -9.026  -10.967 48.928  1.00 32.43  ? 272 THR E C   1 
ATOM   11209 O  O   . THR E 1 272 ? -10.038 -11.495 48.442  1.00 41.12  ? 272 THR E O   1 
ATOM   11210 C  CB  . THR E 1 272 ? -9.131  -9.219  50.628  1.00 30.71  ? 272 THR E CB  1 
ATOM   11211 O  OG1 . THR E 1 272 ? -9.178  -9.096  52.021  1.00 33.73  ? 272 THR E OG1 1 
ATOM   11212 C  CG2 . THR E 1 272 ? -10.495 -8.798  50.138  1.00 33.66  ? 272 THR E CG2 1 
ATOM   11213 N  N   . MET E 1 273 ? -8.008  -10.549 48.171  1.00 27.71  ? 273 MET E N   1 
ATOM   11214 C  CA  . MET E 1 273 ? -8.054  -10.760 46.739  1.00 24.79  ? 273 MET E CA  1 
ATOM   11215 C  C   . MET E 1 273 ? -8.162  -12.245 46.467  1.00 22.64  ? 273 MET E C   1 
ATOM   11216 O  O   . MET E 1 273 ? -8.895  -12.663 45.565  1.00 25.33  ? 273 MET E O   1 
ATOM   11217 C  CB  . MET E 1 273 ? -6.811  -10.149 46.084  1.00 28.63  ? 273 MET E CB  1 
ATOM   11218 C  CG  . MET E 1 273 ? -6.920  -8.646  46.032  1.00 32.64  ? 273 MET E CG  1 
ATOM   11219 S  SD  . MET E 1 273 ? -5.352  -7.912  45.542  1.00 32.00  ? 273 MET E SD  1 
ATOM   11220 C  CE  . MET E 1 273 ? -5.478  -6.128  45.585  1.00 28.20  ? 273 MET E CE  1 
ATOM   11221 N  N   . LEU E 1 274 ? -7.412  -13.050 47.237  1.00 22.22  ? 274 LEU E N   1 
ATOM   11222 C  CA  . LEU E 1 274 ? -7.424  -14.484 46.963  1.00 25.47  ? 274 LEU E CA  1 
ATOM   11223 C  C   . LEU E 1 274 ? -8.798  -15.081 47.267  1.00 29.01  ? 274 LEU E C   1 
ATOM   11224 O  O   . LEU E 1 274 ? -9.243  -15.965 46.497  1.00 29.41  ? 274 LEU E O   1 
ATOM   11225 C  CB  . LEU E 1 274 ? -6.364  -15.240 47.756  1.00 29.42  ? 274 LEU E CB  1 
ATOM   11226 C  CG  . LEU E 1 274 ? -4.909  -15.077 47.320  1.00 30.64  ? 274 LEU E CG  1 
ATOM   11227 C  CD1 . LEU E 1 274 ? -3.986  -15.673 48.334  1.00 32.01  ? 274 LEU E CD1 1 
ATOM   11228 C  CD2 . LEU E 1 274 ? -4.754  -15.759 45.995  1.00 33.57  ? 274 LEU E CD2 1 
ATOM   11229 N  N   . GLU E 1 275 ? -9.437  -14.628 48.381  1.00 28.49  ? 275 GLU E N   1 
ATOM   11230 C  CA  . GLU E 1 275 ? -10.802 -15.079 48.691  1.00 36.28  ? 275 GLU E CA  1 
ATOM   11231 C  C   . GLU E 1 275 ? -11.792 -14.800 47.542  1.00 32.22  ? 275 GLU E C   1 
ATOM   11232 O  O   . GLU E 1 275 ? -12.526 -15.683 47.062  1.00 29.94  ? 275 GLU E O   1 
ATOM   11233 C  CB  . GLU E 1 275 ? -11.335 -14.429 49.961  1.00 38.30  ? 275 GLU E CB  1 
ATOM   11234 C  CG  . GLU E 1 275 ? -10.731 -15.058 51.209  1.00 44.86  ? 275 GLU E CG  1 
ATOM   11235 C  CD  . GLU E 1 275 ? -11.045 -14.394 52.530  1.00 41.76  ? 275 GLU E CD  1 
ATOM   11236 O  OE1 . GLU E 1 275 ? -11.953 -13.548 52.590  1.00 45.15  ? 275 GLU E OE1 1 
ATOM   11237 O  OE2 . GLU E 1 275 ? -10.390 -14.815 53.493  1.00 55.29  ? 275 GLU E OE2 1 
ATOM   11238 N  N   . ARG E 1 276 ? -11.777 -13.551 47.071  1.00 30.70  ? 276 ARG E N   1 
ATOM   11239 C  CA  . ARG E 1 276 ? -12.584 -13.149 45.923  1.00 27.17  ? 276 ARG E CA  1 
ATOM   11240 C  C   . ARG E 1 276 ? -12.379 -14.047 44.719  1.00 24.91  ? 276 ARG E C   1 
ATOM   11241 O  O   . ARG E 1 276 ? -13.346 -14.415 44.055  1.00 24.61  ? 276 ARG E O   1 
ATOM   11242 C  CB  . ARG E 1 276 ? -12.298 -11.685 45.636  1.00 29.06  ? 276 ARG E CB  1 
ATOM   11243 C  CG  . ARG E 1 276 ? -13.068 -10.928 46.708  1.00 32.49  ? 276 ARG E CG  1 
ATOM   11244 C  CD  . ARG E 1 276 ? -12.610 -9.545  46.977  1.00 43.72  ? 276 ARG E CD  1 
ATOM   11245 N  NE  . ARG E 1 276 ? -12.807 -8.736  45.773  1.00 52.87  ? 276 ARG E NE  1 
ATOM   11246 C  CZ  . ARG E 1 276 ? -13.845 -7.993  45.562  1.00 55.80  ? 276 ARG E CZ  1 
ATOM   11247 N  NH1 . ARG E 1 276 ? -14.041 -7.464  44.359  1.00 45.51  ? 276 ARG E NH1 1 
ATOM   11248 N  NH2 . ARG E 1 276 ? -14.708 -7.880  46.557  1.00 56.30  ? 276 ARG E NH2 1 
ATOM   11249 N  N   . MET E 1 277 ? -11.112 -14.380 44.415  1.00 24.87  ? 277 MET E N   1 
ATOM   11250 C  CA  . MET E 1 277 ? -10.835 -15.154 43.217  1.00 22.84  ? 277 MET E CA  1 
ATOM   11251 C  C   . MET E 1 277 ? -11.331 -16.579 43.383  1.00 23.92  ? 277 MET E C   1 
ATOM   11252 O  O   . MET E 1 277 ? -11.878 -17.178 42.466  1.00 25.29  ? 277 MET E O   1 
ATOM   11253 C  CB  . MET E 1 277 ? -9.334  -15.162 42.924  1.00 23.91  ? 277 MET E CB  1 
ATOM   11254 C  CG  . MET E 1 277 ? -8.722  -13.781 42.500  1.00 27.87  ? 277 MET E CG  1 
ATOM   11255 S  SD  . MET E 1 277 ? -6.912  -13.855 42.343  1.00 26.98  ? 277 MET E SD  1 
ATOM   11256 C  CE  . MET E 1 277 ? -6.681  -15.194 41.169  1.00 22.44  ? 277 MET E CE  1 
ATOM   11257 N  N   . PHE E 1 278 ? -11.044 -17.168 44.548  1.00 28.14  ? 278 PHE E N   1 
ATOM   11258 C  CA  . PHE E 1 278 ? -11.225 -18.605 44.733  1.00 30.16  ? 278 PHE E CA  1 
ATOM   11259 C  C   . PHE E 1 278 ? -12.622 -18.931 45.281  1.00 31.23  ? 278 PHE E C   1 
ATOM   11260 O  O   . PHE E 1 278 ? -13.182 -19.981 44.946  1.00 23.56  ? 278 PHE E O   1 
ATOM   11261 C  CB  . PHE E 1 278 ? -10.125 -19.044 45.705  1.00 27.10  ? 278 PHE E CB  1 
ATOM   11262 C  CG  . PHE E 1 278 ? -8.860  -19.392 44.937  1.00 29.12  ? 278 PHE E CG  1 
ATOM   11263 C  CD1 . PHE E 1 278 ? -8.663  -20.693 44.411  1.00 27.24  ? 278 PHE E CD1 1 
ATOM   11264 C  CD2 . PHE E 1 278 ? -7.882  -18.398 44.754  1.00 25.96  ? 278 PHE E CD2 1 
ATOM   11265 C  CE1 . PHE E 1 278 ? -7.550  -20.980 43.638  1.00 27.54  ? 278 PHE E CE1 1 
ATOM   11266 C  CE2 . PHE E 1 278 ? -6.781  -18.674 43.968  1.00 23.75  ? 278 PHE E CE2 1 
ATOM   11267 C  CZ  . PHE E 1 278 ? -6.608  -19.954 43.430  1.00 26.30  ? 278 PHE E CZ  1 
ATOM   11268 N  N   . LEU E 1 279 ? -13.163 -18.002 46.088  1.00 33.03  ? 279 LEU E N   1 
ATOM   11269 C  CA  . LEU E 1 279 ? -14.446 -18.280 46.723  1.00 45.67  ? 279 LEU E CA  1 
ATOM   11270 C  C   . LEU E 1 279 ? -15.584 -17.528 46.038  1.00 42.83  ? 279 LEU E C   1 
ATOM   11271 O  O   . LEU E 1 279 ? -16.736 -17.915 46.160  1.00 41.34  ? 279 LEU E O   1 
ATOM   11272 C  CB  . LEU E 1 279 ? -14.385 -17.924 48.213  1.00 36.53  ? 279 LEU E CB  1 
ATOM   11273 C  CG  . LEU E 1 279 ? -13.356 -18.722 49.013  1.00 33.89  ? 279 LEU E CG  1 
ATOM   11274 C  CD1 . LEU E 1 279 ? -13.435 -18.094 50.399  1.00 33.41  ? 279 LEU E CD1 1 
ATOM   11275 C  CD2 . LEU E 1 279 ? -13.471 -20.273 48.962  1.00 30.94  ? 279 LEU E CD2 1 
ATOM   11276 N  N   . GLY E 1 280 ? -15.296 -16.435 45.355  1.00 39.01  ? 280 GLY E N   1 
ATOM   11277 C  CA  . GLY E 1 280 ? -16.359 -15.787 44.614  1.00 41.48  ? 280 GLY E CA  1 
ATOM   11278 C  C   . GLY E 1 280 ? -16.960 -14.653 45.450  1.00 44.24  ? 280 GLY E C   1 
ATOM   11279 O  O   . GLY E 1 280 ? -16.559 -14.441 46.602  1.00 35.24  ? 280 GLY E O   1 
ATOM   11280 N  N   . THR E 1 281 ? -17.901 -13.924 44.827  1.00 40.74  ? 281 THR E N   1 
ATOM   11281 C  CA  . THR E 1 281 ? -18.631 -12.850 45.470  1.00 46.78  ? 281 THR E CA  1 
ATOM   11282 C  C   . THR E 1 281 ? -20.112 -13.108 45.254  1.00 59.95  ? 281 THR E C   1 
ATOM   11283 O  O   . THR E 1 281 ? -20.458 -14.155 44.702  1.00 60.73  ? 281 THR E O   1 
ATOM   11284 C  CB  . THR E 1 281 ? -18.244 -11.488 44.918  1.00 45.00  ? 281 THR E CB  1 
ATOM   11285 O  OG1 . THR E 1 281 ? -18.600 -11.532 43.529  1.00 41.95  ? 281 THR E OG1 1 
ATOM   11286 C  CG2 . THR E 1 281 ? -16.810 -11.174 45.283  1.00 47.61  ? 281 THR E CG2 1 
ATOM   11287 N  N   . ALA E 1 282 ? -20.960 -12.146 45.672  1.00 70.72  ? 282 ALA E N   1 
ATOM   11288 C  CA  . ALA E 1 282 ? -22.395 -12.235 45.423  1.00 62.64  ? 282 ALA E CA  1 
ATOM   11289 C  C   . ALA E 1 282 ? -22.657 -12.428 43.922  1.00 67.41  ? 282 ALA E C   1 
ATOM   11290 O  O   . ALA E 1 282 ? -23.424 -13.315 43.552  1.00 51.36  ? 282 ALA E O   1 
ATOM   11291 C  CB  . ALA E 1 282 ? -23.101 -11.023 45.995  1.00 55.98  ? 282 ALA E CB  1 
ATOM   11292 N  N   . SER E 1 283 ? -21.949 -11.665 43.065  1.00 66.86  ? 283 SER E N   1 
ATOM   11293 C  CA  . SER E 1 283 ? -22.191 -11.674 41.630  1.00 64.84  ? 283 SER E CA  1 
ATOM   11294 C  C   . SER E 1 283 ? -21.214 -12.537 40.803  1.00 54.06  ? 283 SER E C   1 
ATOM   11295 O  O   . SER E 1 283 ? -21.306 -12.541 39.589  1.00 56.02  ? 283 SER E O   1 
ATOM   11296 C  CB  . SER E 1 283 ? -22.186 -10.247 41.146  1.00 60.46  ? 283 SER E CB  1 
ATOM   11297 O  OG  . SER E 1 283 ? -21.074 -9.557  41.691  1.00 66.42  ? 283 SER E OG  1 
ATOM   11298 N  N   . ALA E 1 284 ? -20.268 -13.263 41.393  1.00 46.06  ? 284 ALA E N   1 
ATOM   11299 C  CA  . ALA E 1 284 ? -19.287 -13.974 40.583  1.00 43.48  ? 284 ALA E CA  1 
ATOM   11300 C  C   . ALA E 1 284 ? -18.932 -15.307 41.250  1.00 36.38  ? 284 ALA E C   1 
ATOM   11301 O  O   . ALA E 1 284 ? -18.471 -15.357 42.393  1.00 36.30  ? 284 ALA E O   1 
ATOM   11302 C  CB  . ALA E 1 284 ? -18.059 -13.081 40.334  1.00 36.77  ? 284 ALA E CB  1 
ATOM   11303 N  N   . PRO E 1 285 ? -19.124 -16.444 40.572  1.00 31.45  ? 285 PRO E N   1 
ATOM   11304 C  CA  . PRO E 1 285 ? -18.735 -17.727 41.162  1.00 35.89  ? 285 PRO E CA  1 
ATOM   11305 C  C   . PRO E 1 285 ? -17.253 -17.845 41.554  1.00 41.69  ? 285 PRO E C   1 
ATOM   11306 O  O   . PRO E 1 285 ? -16.933 -18.405 42.611  1.00 44.61  ? 285 PRO E O   1 
ATOM   11307 C  CB  . PRO E 1 285 ? -19.164 -18.755 40.074  1.00 35.15  ? 285 PRO E CB  1 
ATOM   11308 C  CG  . PRO E 1 285 ? -19.252 -17.945 38.780  1.00 37.23  ? 285 PRO E CG  1 
ATOM   11309 C  CD  . PRO E 1 285 ? -19.708 -16.560 39.237  1.00 31.93  ? 285 PRO E CD  1 
ATOM   11310 N  N   . HIS E 1 286 ? -16.358 -17.353 40.672  1.00 42.41  ? 286 HIS E N   1 
ATOM   11311 C  CA  . HIS E 1 286 ? -14.917 -17.315 40.881  1.00 33.71  ? 286 HIS E CA  1 
ATOM   11312 C  C   . HIS E 1 286 ? -14.291 -16.541 39.722  1.00 39.19  ? 286 HIS E C   1 
ATOM   11313 O  O   . HIS E 1 286 ? -14.934 -16.298 38.692  1.00 40.50  ? 286 HIS E O   1 
ATOM   11314 C  CB  . HIS E 1 286 ? -14.370 -18.730 40.884  1.00 29.90  ? 286 HIS E CB  1 
ATOM   11315 C  CG  . HIS E 1 286 ? -14.686 -19.504 39.657  1.00 32.53  ? 286 HIS E CG  1 
ATOM   11316 N  ND1 . HIS E 1 286 ? -15.598 -20.530 39.642  1.00 35.63  ? 286 HIS E ND1 1 
ATOM   11317 C  CD2 . HIS E 1 286 ? -14.125 -19.500 38.446  1.00 36.18  ? 286 HIS E CD2 1 
ATOM   11318 C  CE1 . HIS E 1 286 ? -15.543 -21.126 38.462  1.00 36.50  ? 286 HIS E CE1 1 
ATOM   11319 N  NE2 . HIS E 1 286 ? -14.621 -20.540 37.718  1.00 33.50  ? 286 HIS E NE2 1 
ATOM   11320 N  N   . ASP E 1 287 ? -13.026 -16.170 39.892  1.00 34.31  ? 287 ASP E N   1 
ATOM   11321 C  CA  . ASP E 1 287 ? -12.240 -15.522 38.848  1.00 30.10  ? 287 ASP E CA  1 
ATOM   11322 C  C   . ASP E 1 287 ? -12.070 -16.432 37.637  1.00 24.59  ? 287 ASP E C   1 
ATOM   11323 O  O   . ASP E 1 287 ? -11.499 -17.537 37.751  1.00 25.85  ? 287 ASP E O   1 
ATOM   11324 C  CB  . ASP E 1 287 ? -10.890 -15.156 39.442  1.00 28.86  ? 287 ASP E CB  1 
ATOM   11325 C  CG  . ASP E 1 287 ? -10.017 -14.239 38.594  1.00 30.86  ? 287 ASP E CG  1 
ATOM   11326 O  OD1 . ASP E 1 287 ? -10.144 -14.290 37.344  1.00 34.00  ? 287 ASP E OD1 1 
ATOM   11327 O  OD2 . ASP E 1 287 ? -9.264  -13.430 39.187  1.00 31.82  ? 287 ASP E OD2 1 
ATOM   11328 N  N   . ARG E 1 288 ? -12.497 -15.958 36.453  1.00 23.99  ? 288 ARG E N   1 
ATOM   11329 C  CA  . ARG E 1 288 ? -12.391 -16.816 35.259  1.00 26.28  ? 288 ARG E CA  1 
ATOM   11330 C  C   . ARG E 1 288 ? -10.959 -17.239 34.897  1.00 23.41  ? 288 ARG E C   1 
ATOM   11331 O  O   . ARG E 1 288 ? -10.761 -18.249 34.238  1.00 25.17  ? 288 ARG E O   1 
ATOM   11332 C  CB  . ARG E 1 288 ? -13.029 -16.108 34.076  1.00 30.51  ? 288 ARG E CB  1 
ATOM   11333 C  CG  . ARG E 1 288 ? -14.543 -16.117 34.120  1.00 37.34  ? 288 ARG E CG  1 
ATOM   11334 C  CD  . ARG E 1 288 ? -14.984 -17.436 33.525  1.00 35.46  ? 288 ARG E CD  1 
ATOM   11335 N  NE  . ARG E 1 288 ? -15.001 -17.453 32.055  1.00 38.33  ? 288 ARG E NE  1 
ATOM   11336 C  CZ  . ARG E 1 288 ? -14.653 -18.527 31.287  1.00 48.77  ? 288 ARG E CZ  1 
ATOM   11337 N  NH1 . ARG E 1 288 ? -14.287 -19.705 31.830  1.00 57.92  ? 288 ARG E NH1 1 
ATOM   11338 N  NH2 . ARG E 1 288 ? -14.664 -18.439 29.967  1.00 42.55  ? 288 ARG E NH2 1 
ATOM   11339 N  N   . ILE E 1 289 ? -9.953  -16.497 35.372  1.00 24.66  ? 289 ILE E N   1 
ATOM   11340 C  CA  . ILE E 1 289 ? -8.587  -16.842 35.059  1.00 26.01  ? 289 ILE E CA  1 
ATOM   11341 C  C   . ILE E 1 289 ? -8.247  -18.208 35.615  1.00 26.26  ? 289 ILE E C   1 
ATOM   11342 O  O   . ILE E 1 289 ? -7.387  -18.876 35.030  1.00 26.98  ? 289 ILE E O   1 
ATOM   11343 C  CB  . ILE E 1 289 ? -7.608  -15.756 35.535  1.00 32.19  ? 289 ILE E CB  1 
ATOM   11344 C  CG1 . ILE E 1 289 ? -6.417  -15.629 34.576  1.00 31.12  ? 289 ILE E CG1 1 
ATOM   11345 C  CG2 . ILE E 1 289 ? -7.168  -15.945 36.986  1.00 29.77  ? 289 ILE E CG2 1 
ATOM   11346 C  CD1 . ILE E 1 289 ? -5.593  -14.348 34.793  1.00 31.26  ? 289 ILE E CD1 1 
ATOM   11347 N  N   . LEU E 1 290 ? -8.961  -18.646 36.662  1.00 22.16  ? 290 LEU E N   1 
ATOM   11348 C  CA  . LEU E 1 290 ? -8.669  -19.916 37.323  1.00 23.02  ? 290 LEU E CA  1 
ATOM   11349 C  C   . LEU E 1 290 ? -9.211  -21.075 36.514  1.00 21.19  ? 290 LEU E C   1 
ATOM   11350 O  O   . LEU E 1 290 ? -8.819  -22.234 36.727  1.00 24.05  ? 290 LEU E O   1 
ATOM   11351 C  CB  . LEU E 1 290 ? -9.227  -19.932 38.744  1.00 25.75  ? 290 LEU E CB  1 
ATOM   11352 C  CG  . LEU E 1 290 ? -8.663  -18.903 39.718  1.00 25.98  ? 290 LEU E CG  1 
ATOM   11353 C  CD1 . LEU E 1 290 ? -9.362  -18.924 41.036  1.00 26.76  ? 290 LEU E CD1 1 
ATOM   11354 C  CD2 . LEU E 1 290 ? -7.189  -19.163 39.962  1.00 27.61  ? 290 LEU E CD2 1 
ATOM   11355 N  N   . ASP E 1 291 ? -10.086 -20.775 35.541  1.00 26.90  ? 291 ASP E N   1 
ATOM   11356 C  CA  . ASP E 1 291 ? -10.487 -21.841 34.609  1.00 28.01  ? 291 ASP E CA  1 
ATOM   11357 C  C   . ASP E 1 291 ? -9.345  -22.204 33.655  1.00 31.12  ? 291 ASP E C   1 
ATOM   11358 O  O   . ASP E 1 291 ? -9.457  -23.210 32.975  1.00 30.89  ? 291 ASP E O   1 
ATOM   11359 C  CB  . ASP E 1 291 ? -11.796 -21.606 33.870  1.00 30.20  ? 291 ASP E CB  1 
ATOM   11360 C  CG  . ASP E 1 291 ? -13.022 -21.450 34.774  1.00 29.90  ? 291 ASP E CG  1 
ATOM   11361 O  OD1 . ASP E 1 291 ? -13.117 -22.174 35.803  1.00 29.06  ? 291 ASP E OD1 1 
ATOM   11362 O  OD2 . ASP E 1 291 ? -13.795 -20.501 34.514  1.00 33.28  ? 291 ASP E OD2 1 
ATOM   11363 N  N   . PHE E 1 292 ? -8.233  -21.433 33.636  1.00 31.10  ? 292 PHE E N   1 
ATOM   11364 C  CA  . PHE E 1 292 ? -7.090  -21.745 32.786  1.00 30.56  ? 292 PHE E CA  1 
ATOM   11365 C  C   . PHE E 1 292 ? -5.809  -21.849 33.590  1.00 25.85  ? 292 PHE E C   1 
ATOM   11366 O  O   . PHE E 1 292 ? -4.759  -21.955 33.000  1.00 25.11  ? 292 PHE E O   1 
ATOM   11367 C  CB  . PHE E 1 292 ? -6.955  -20.632 31.719  1.00 31.21  ? 292 PHE E CB  1 
ATOM   11368 C  CG  . PHE E 1 292 ? -8.262  -20.538 30.939  1.00 34.26  ? 292 PHE E CG  1 
ATOM   11369 C  CD1 . PHE E 1 292 ? -8.538  -21.459 29.908  1.00 31.82  ? 292 PHE E CD1 1 
ATOM   11370 C  CD2 . PHE E 1 292 ? -9.262  -19.630 31.332  1.00 27.84  ? 292 PHE E CD2 1 
ATOM   11371 C  CE1 . PHE E 1 292 ? -9.729  -21.407 29.252  1.00 26.58  ? 292 PHE E CE1 1 
ATOM   11372 C  CE2 . PHE E 1 292 ? -10.453 -19.581 30.646  1.00 28.28  ? 292 PHE E CE2 1 
ATOM   11373 C  CZ  . PHE E 1 292 ? -10.696 -20.481 29.648  1.00 25.66  ? 292 PHE E CZ  1 
ATOM   11374 N  N   . SER E 1 293 ? -5.904  -21.741 34.907  1.00 25.63  ? 293 SER E N   1 
ATOM   11375 C  CA  . SER E 1 293 ? -4.719  -21.656 35.724  1.00 28.44  ? 293 SER E CA  1 
ATOM   11376 C  C   . SER E 1 293 ? -4.941  -22.462 36.998  1.00 28.02  ? 293 SER E C   1 
ATOM   11377 O  O   . SER E 1 293 ? -5.863  -22.146 37.705  1.00 30.01  ? 293 SER E O   1 
ATOM   11378 C  CB  . SER E 1 293 ? -4.393  -20.168 36.031  1.00 30.09  ? 293 SER E CB  1 
ATOM   11379 O  OG  . SER E 1 293 ? -4.611  -19.294 34.934  1.00 26.89  ? 293 SER E OG  1 
ATOM   11380 N  N   . THR E 1 294 ? -4.008  -23.344 37.352  1.00 26.09  ? 294 THR E N   1 
ATOM   11381 C  CA  . THR E 1 294 ? -4.064  -24.145 38.569  1.00 26.05  ? 294 THR E CA  1 
ATOM   11382 C  C   . THR E 1 294 ? -2.904  -23.769 39.490  1.00 29.55  ? 294 THR E C   1 
ATOM   11383 O  O   . THR E 1 294 ? -1.750  -23.903 39.050  1.00 26.39  ? 294 THR E O   1 
ATOM   11384 C  CB  . THR E 1 294 ? -3.886  -25.606 38.164  1.00 26.63  ? 294 THR E CB  1 
ATOM   11385 O  OG1 . THR E 1 294 ? -5.037  -25.913 37.429  1.00 27.10  ? 294 THR E OG1 1 
ATOM   11386 C  CG2 . THR E 1 294 ? -3.942  -26.560 39.324  1.00 29.39  ? 294 THR E CG2 1 
ATOM   11387 N  N   . ALA E 1 295 ? -3.190  -23.376 40.749  1.00 26.55  ? 295 ALA E N   1 
ATOM   11388 C  CA  . ALA E 1 295 ? -2.131  -23.133 41.742  1.00 26.57  ? 295 ALA E CA  1 
ATOM   11389 C  C   . ALA E 1 295 ? -1.572  -24.454 42.274  1.00 25.96  ? 295 ALA E C   1 
ATOM   11390 O  O   . ALA E 1 295 ? -2.337  -25.324 42.592  1.00 29.24  ? 295 ALA E O   1 
ATOM   11391 C  CB  . ALA E 1 295 ? -2.659  -22.309 42.876  1.00 25.09  ? 295 ALA E CB  1 
ATOM   11392 N  N   . VAL E 1 296 ? -0.261  -24.677 42.273  1.00 25.54  ? 296 VAL E N   1 
ATOM   11393 C  CA  . VAL E 1 296 ? 0.300   -25.909 42.811  1.00 22.58  ? 296 VAL E CA  1 
ATOM   11394 C  C   . VAL E 1 296 ? 1.279   -25.640 43.944  1.00 22.02  ? 296 VAL E C   1 
ATOM   11395 O  O   . VAL E 1 296 ? 1.833   -26.582 44.497  1.00 25.99  ? 296 VAL E O   1 
ATOM   11396 C  CB  . VAL E 1 296 ? 0.979   -26.789 41.761  1.00 27.66  ? 296 VAL E CB  1 
ATOM   11397 C  CG1 . VAL E 1 296 ? 0.015   -27.179 40.675  1.00 29.32  ? 296 VAL E CG1 1 
ATOM   11398 C  CG2 . VAL E 1 296 ? 2.130   -26.056 41.121  1.00 29.45  ? 296 VAL E CG2 1 
ATOM   11399 N  N   . THR E 1 297 ? 1.509   -24.382 44.314  1.00 21.28  ? 297 THR E N   1 
ATOM   11400 C  CA  . THR E 1 297 ? 2.193   -24.065 45.550  1.00 22.66  ? 297 THR E CA  1 
ATOM   11401 C  C   . THR E 1 297 ? 1.493   -22.872 46.183  1.00 19.85  ? 297 THR E C   1 
ATOM   11402 O  O   . THR E 1 297 ? 0.758   -22.127 45.531  1.00 22.96  ? 297 THR E O   1 
ATOM   11403 C  CB  . THR E 1 297 ? 3.663   -23.711 45.335  1.00 22.89  ? 297 THR E CB  1 
ATOM   11404 O  OG1 . THR E 1 297 ? 3.851   -22.476 44.670  1.00 24.16  ? 297 THR E OG1 1 
ATOM   11405 C  CG2 . THR E 1 297 ? 4.418   -24.771 44.585  1.00 22.23  ? 297 THR E CG2 1 
ATOM   11406 N  N   . GLY E 1 298 ? 1.785   -22.686 47.450  1.00 20.24  ? 298 GLY E N   1 
ATOM   11407 C  CA  . GLY E 1 298 ? 1.213   -21.549 48.154  1.00 21.73  ? 298 GLY E CA  1 
ATOM   11408 C  C   . GLY E 1 298 ? 1.946   -21.310 49.466  1.00 24.37  ? 298 GLY E C   1 
ATOM   11409 O  O   . GLY E 1 298 ? 1.964   -22.184 50.296  1.00 23.75  ? 298 GLY E O   1 
ATOM   11410 N  N   . SER E 1 299 ? 2.555   -20.126 49.641  1.00 26.06  ? 299 SER E N   1 
ATOM   11411 C  CA  . SER E 1 299 ? 3.291   -19.839 50.840  1.00 22.22  ? 299 SER E CA  1 
ATOM   11412 C  C   . SER E 1 299 ? 3.228   -18.343 51.076  1.00 22.61  ? 299 SER E C   1 
ATOM   11413 O  O   . SER E 1 299 ? 3.012   -17.540 50.149  1.00 22.88  ? 299 SER E O   1 
ATOM   11414 C  CB  . SER E 1 299 ? 4.693   -20.306 50.720  1.00 25.65  ? 299 SER E CB  1 
ATOM   11415 O  OG  . SER E 1 299 ? 4.740   -21.631 50.219  1.00 26.32  ? 299 SER E OG  1 
ATOM   11416 N  N   . LEU E 1 300 ? 3.511   -18.017 52.320  1.00 21.94  ? 300 LEU E N   1 
ATOM   11417 C  CA  . LEU E 1 300 ? 3.439   -16.635 52.784  1.00 28.32  ? 300 LEU E CA  1 
ATOM   11418 C  C   . LEU E 1 300 ? 4.709   -16.385 53.608  1.00 24.15  ? 300 LEU E C   1 
ATOM   11419 O  O   . LEU E 1 300 ? 5.070   -17.217 54.470  1.00 21.52  ? 300 LEU E O   1 
ATOM   11420 C  CB  . LEU E 1 300 ? 2.158   -16.403 53.616  1.00 28.29  ? 300 LEU E CB  1 
ATOM   11421 C  CG  . LEU E 1 300 ? 1.864   -14.976 54.070  1.00 28.08  ? 300 LEU E CG  1 
ATOM   11422 C  CD1 . LEU E 1 300 ? 0.450   -14.956 54.610  1.00 34.43  ? 300 LEU E CD1 1 
ATOM   11423 C  CD2 . LEU E 1 300 ? 2.756   -14.501 55.090  1.00 25.57  ? 300 LEU E CD2 1 
ATOM   11424 N  N   . PHE E 1 301 ? 5.350   -15.231 53.351  1.00 21.87  ? 301 PHE E N   1 
ATOM   11425 C  CA  . PHE E 1 301 ? 6.569   -14.854 54.027  1.00 21.70  ? 301 PHE E CA  1 
ATOM   11426 C  C   . PHE E 1 301 ? 6.508   -13.385 54.444  1.00 22.36  ? 301 PHE E C   1 
ATOM   11427 O  O   . PHE E 1 301 ? 5.781   -12.547 53.868  1.00 22.40  ? 301 PHE E O   1 
ATOM   11428 C  CB  . PHE E 1 301 ? 7.757   -14.998 53.080  1.00 22.66  ? 301 PHE E CB  1 
ATOM   11429 C  CG  . PHE E 1 301 ? 7.881   -16.366 52.453  1.00 19.60  ? 301 PHE E CG  1 
ATOM   11430 C  CD1 . PHE E 1 301 ? 8.604   -17.359 53.101  1.00 20.49  ? 301 PHE E CD1 1 
ATOM   11431 C  CD2 . PHE E 1 301 ? 7.232   -16.645 51.264  1.00 17.53  ? 301 PHE E CD2 1 
ATOM   11432 C  CE1 . PHE E 1 301 ? 8.707   -18.625 52.521  1.00 21.49  ? 301 PHE E CE1 1 
ATOM   11433 C  CE2 . PHE E 1 301 ? 7.332   -17.889 50.693  1.00 19.76  ? 301 PHE E CE2 1 
ATOM   11434 C  CZ  . PHE E 1 301 ? 8.085   -18.869 51.317  1.00 21.38  ? 301 PHE E CZ  1 
ATOM   11435 N  N   . PHE E 1 302 ? 7.321   -13.107 55.467  1.00 23.12  ? 302 PHE E N   1 
ATOM   11436 C  CA  . PHE E 1 302 ? 7.659   -11.765 55.878  1.00 23.49  ? 302 PHE E CA  1 
ATOM   11437 C  C   . PHE E 1 302 ? 9.070   -11.468 55.357  1.00 23.69  ? 302 PHE E C   1 
ATOM   11438 O  O   . PHE E 1 302 ? 10.033  -12.221 55.589  1.00 20.49  ? 302 PHE E O   1 
ATOM   11439 C  CB  . PHE E 1 302 ? 7.555   -11.614 57.399  1.00 22.72  ? 302 PHE E CB  1 
ATOM   11440 C  CG  . PHE E 1 302 ? 7.800   -10.185 57.838  1.00 22.69  ? 302 PHE E CG  1 
ATOM   11441 C  CD1 . PHE E 1 302 ? 6.866   -9.184  57.579  1.00 25.94  ? 302 PHE E CD1 1 
ATOM   11442 C  CD2 . PHE E 1 302 ? 8.964   -9.822  58.460  1.00 22.65  ? 302 PHE E CD2 1 
ATOM   11443 C  CE1 . PHE E 1 302 ? 7.104   -7.859  57.971  1.00 25.21  ? 302 PHE E CE1 1 
ATOM   11444 C  CE2 . PHE E 1 302 ? 9.185   -8.497  58.808  1.00 22.85  ? 302 PHE E CE2 1 
ATOM   11445 C  CZ  . PHE E 1 302 ? 8.264   -7.535  58.587  1.00 22.77  ? 302 PHE E CZ  1 
ATOM   11446 N  N   . THR E 1 303 ? 9.179   -10.311 54.676  1.00 25.93  ? 303 THR E N   1 
ATOM   11447 C  CA  . THR E 1 303 ? 10.435  -9.816  54.156  1.00 24.84  ? 303 THR E CA  1 
ATOM   11448 C  C   . THR E 1 303 ? 10.870  -8.642  55.014  1.00 24.71  ? 303 THR E C   1 
ATOM   11449 O  O   . THR E 1 303 ? 10.419  -7.542  54.795  1.00 27.16  ? 303 THR E O   1 
ATOM   11450 C  CB  . THR E 1 303 ? 10.330  -9.446  52.676  1.00 23.04  ? 303 THR E CB  1 
ATOM   11451 O  OG1 . THR E 1 303 ? 9.440   -8.377  52.426  1.00 23.81  ? 303 THR E OG1 1 
ATOM   11452 C  CG2 . THR E 1 303 ? 9.903   -10.615 51.803  1.00 25.58  ? 303 THR E CG2 1 
ATOM   11453 N  N   . PRO E 1 304 ? 11.753  -8.855  56.019  1.00 24.52  ? 304 PRO E N   1 
ATOM   11454 C  CA  . PRO E 1 304 ? 12.123  -7.791  56.952  1.00 24.39  ? 304 PRO E CA  1 
ATOM   11455 C  C   . PRO E 1 304 ? 12.899  -6.674  56.274  1.00 31.72  ? 304 PRO E C   1 
ATOM   11456 O  O   . PRO E 1 304 ? 13.463  -6.857  55.160  1.00 27.64  ? 304 PRO E O   1 
ATOM   11457 C  CB  . PRO E 1 304 ? 12.984  -8.425  58.005  1.00 27.29  ? 304 PRO E CB  1 
ATOM   11458 C  CG  . PRO E 1 304 ? 13.236  -9.888  57.508  1.00 28.68  ? 304 PRO E CG  1 
ATOM   11459 C  CD  . PRO E 1 304 ? 12.429  -10.133 56.274  1.00 25.08  ? 304 PRO E CD  1 
ATOM   11460 N  N   . ALA E 1 305 ? 12.949  -5.541  56.992  1.00 27.85  ? 305 ALA E N   1 
ATOM   11461 C  CA  . ALA E 1 305 ? 13.869  -4.471  56.618  1.00 29.45  ? 305 ALA E CA  1 
ATOM   11462 C  C   . ALA E 1 305 ? 15.299  -4.983  56.544  1.00 32.56  ? 305 ALA E C   1 
ATOM   11463 O  O   . ALA E 1 305 ? 15.689  -5.920  57.267  1.00 30.56  ? 305 ALA E O   1 
ATOM   11464 C  CB  . ALA E 1 305 ? 13.782  -3.319  57.578  1.00 31.03  ? 305 ALA E CB  1 
ATOM   11465 N  N   . ALA E 1 306 ? 16.082  -4.377  55.628  1.00 36.31  ? 306 ALA E N   1 
ATOM   11466 C  CA  . ALA E 1 306 ? 17.451  -4.827  55.396  1.00 38.52  ? 306 ALA E CA  1 
ATOM   11467 C  C   . ALA E 1 306 ? 18.276  -4.803  56.691  1.00 36.69  ? 306 ALA E C   1 
ATOM   11468 O  O   . ALA E 1 306 ? 19.033  -5.753  56.939  1.00 29.10  ? 306 ALA E O   1 
ATOM   11469 C  CB  . ALA E 1 306 ? 18.077  -4.003  54.294  1.00 33.91  ? 306 ALA E CB  1 
ATOM   11470 N  N   . ASP E 1 307 ? 18.068  -3.756  57.527  1.00 41.58  ? 307 ASP E N   1 
ATOM   11471 C  CA  . ASP E 1 307 ? 18.858  -3.577  58.745  1.00 47.11  ? 307 ASP E CA  1 
ATOM   11472 C  C   . ASP E 1 307 ? 18.576  -4.702  59.752  1.00 44.95  ? 307 ASP E C   1 
ATOM   11473 O  O   . ASP E 1 307 ? 19.506  -5.149  60.446  1.00 37.45  ? 307 ASP E O   1 
ATOM   11474 C  CB  . ASP E 1 307 ? 18.762  -2.219  59.433  1.00 47.78  ? 307 ASP E CB  1 
ATOM   11475 C  CG  . ASP E 1 307 ? 17.664  -1.286  58.988  1.00 59.42  ? 307 ASP E CG  1 
ATOM   11476 O  OD1 . ASP E 1 307 ? 17.862  -0.652  57.941  1.00 84.95  ? 307 ASP E OD1 1 
ATOM   11477 O  OD2 . ASP E 1 307 ? 16.646  -1.215  59.692  1.00 75.09  ? 307 ASP E OD2 1 
ATOM   11478 N  N   . PHE E 1 308 ? 17.329  -5.202  59.774  1.00 32.18  ? 308 PHE E N   1 
ATOM   11479 C  CA  . PHE E 1 308 ? 17.026  -6.303  60.681  1.00 35.19  ? 308 PHE E CA  1 
ATOM   11480 C  C   . PHE E 1 308 ? 17.977  -7.475  60.422  1.00 38.17  ? 308 PHE E C   1 
ATOM   11481 O  O   . PHE E 1 308 ? 18.510  -8.092  61.371  1.00 36.12  ? 308 PHE E O   1 
ATOM   11482 C  CB  . PHE E 1 308 ? 15.539  -6.661  60.563  1.00 36.36  ? 308 PHE E CB  1 
ATOM   11483 C  CG  . PHE E 1 308 ? 15.142  -7.862  61.397  1.00 32.47  ? 308 PHE E CG  1 
ATOM   11484 C  CD1 . PHE E 1 308 ? 15.382  -9.149  60.921  1.00 32.94  ? 308 PHE E CD1 1 
ATOM   11485 C  CD2 . PHE E 1 308 ? 14.572  -7.678  62.662  1.00 33.04  ? 308 PHE E CD2 1 
ATOM   11486 C  CE1 . PHE E 1 308 ? 15.071  -10.247 61.710  1.00 41.99  ? 308 PHE E CE1 1 
ATOM   11487 C  CE2 . PHE E 1 308 ? 14.237  -8.771  63.430  1.00 35.73  ? 308 PHE E CE2 1 
ATOM   11488 C  CZ  . PHE E 1 308 ? 14.495  -10.063 62.962  1.00 39.97  ? 308 PHE E CZ  1 
ATOM   11489 N  N   . LEU E 1 309 ? 18.193  -7.783  59.128  1.00 38.13  ? 309 LEU E N   1 
ATOM   11490 C  CA  . LEU E 1 309 ? 18.983  -8.957  58.792  1.00 38.77  ? 309 LEU E CA  1 
ATOM   11491 C  C   . LEU E 1 309 ? 20.463  -8.700  59.060  1.00 42.71  ? 309 LEU E C   1 
ATOM   11492 O  O   . LEU E 1 309 ? 21.153  -9.639  59.490  1.00 39.05  ? 309 LEU E O   1 
ATOM   11493 C  CB  . LEU E 1 309 ? 18.783  -9.361  57.335  1.00 37.96  ? 309 LEU E CB  1 
ATOM   11494 C  CG  . LEU E 1 309 ? 17.371  -9.672  56.860  1.00 33.50  ? 309 LEU E CG  1 
ATOM   11495 C  CD1 . LEU E 1 309 ? 17.441  -9.848  55.373  1.00 35.54  ? 309 LEU E CD1 1 
ATOM   11496 C  CD2 . LEU E 1 309 ? 16.950  -10.975 57.464  1.00 42.21  ? 309 LEU E CD2 1 
ATOM   11497 N  N   . GLU E 1 310 ? 20.928  -7.459  58.756  1.00 43.52  ? 310 GLU E N   1 
ATOM   11498 C  CA  . GLU E 1 310 ? 22.337  -7.102  58.864  1.00 50.71  ? 310 GLU E CA  1 
ATOM   11499 C  C   . GLU E 1 310 ? 22.841  -7.372  60.283  1.00 50.53  ? 310 GLU E C   1 
ATOM   11500 O  O   . GLU E 1 310 ? 23.927  -7.941  60.413  1.00 53.64  ? 310 GLU E O   1 
ATOM   11501 C  CB  . GLU E 1 310 ? 22.612  -5.678  58.369  1.00 55.81  ? 310 GLU E CB  1 
ATOM   11502 C  CG  . GLU E 1 310 ? 24.088  -5.455  58.029  1.00 60.63  ? 310 GLU E CG  1 
ATOM   11503 C  CD  . GLU E 1 310 ? 24.269  -4.259  57.107  1.00 76.86  ? 310 GLU E CD  1 
ATOM   11504 O  OE1 . GLU E 1 310 ? 24.838  -4.432  55.997  1.00 80.08  ? 310 GLU E OE1 1 
ATOM   11505 O  OE2 . GLU E 1 310 ? 23.804  -3.155  57.488  1.00 83.03  ? 310 GLU E OE2 1 
ATOM   11506 N  N   . ASP E 1 311 ? 21.999  -7.089  61.308  1.00 61.28  ? 311 ASP E N   1 
ATOM   11507 C  CA  . ASP E 1 311 ? 22.340  -7.224  62.724  1.00 70.29  ? 311 ASP E CA  1 
ATOM   11508 C  C   . ASP E 1 311 ? 22.047  -8.612  63.334  1.00 65.35  ? 311 ASP E C   1 
ATOM   11509 O  O   . ASP E 1 311 ? 21.163  -8.683  64.176  1.00 70.65  ? 311 ASP E O   1 
ATOM   11510 C  CB  . ASP E 1 311 ? 21.493  -6.266  63.565  1.00 66.16  ? 311 ASP E CB  1 
ATOM   11511 C  CG  . ASP E 1 311 ? 21.387  -4.806  63.122  1.00 75.27  ? 311 ASP E CG  1 
ATOM   11512 O  OD1 . ASP E 1 311 ? 22.190  -4.307  62.295  1.00 79.63  ? 311 ASP E OD1 1 
ATOM   11513 O  OD2 . ASP E 1 311 ? 20.490  -4.126  63.632  1.00 72.54  ? 311 ASP E OD2 1 
ATOM   11514 N  N   . LEU E 1 312 ? 22.802  -9.694  63.041  1.00 68.26  ? 312 LEU E N   1 
ATOM   11515 C  CA  . LEU E 1 312 ? 22.511  -11.010 63.638  1.00 74.61  ? 312 LEU E CA  1 
ATOM   11516 C  C   . LEU E 1 312 ? 23.829  -11.757 64.015  1.00 66.45  ? 312 LEU E C   1 
ATOM   11517 O  O   . LEU E 1 312 ? 24.924  -11.213 63.736  1.00 63.33  ? 312 LEU E O   1 
ATOM   11518 C  CB  . LEU E 1 312 ? 21.590  -11.955 62.826  1.00 65.28  ? 312 LEU E CB  1 
ATOM   11519 C  CG  . LEU E 1 312 ? 20.328  -11.430 62.108  1.00 51.79  ? 312 LEU E CG  1 
ATOM   11520 C  CD1 . LEU E 1 312 ? 19.766  -12.563 61.265  1.00 46.07  ? 312 LEU E CD1 1 
ATOM   11521 C  CD2 . LEU E 1 312 ? 19.176  -10.815 62.912  1.00 49.31  ? 312 LEU E CD2 1 
ATOM   11522 N  N   . GLU F 1 7   ? 17.371  20.267  52.270  1.00 108.48 ? 7   GLU F N   1 
ATOM   11523 C  CA  . GLU F 1 7   ? 18.677  20.534  51.611  1.00 102.93 ? 7   GLU F CA  1 
ATOM   11524 C  C   . GLU F 1 7   ? 18.931  22.067  51.537  1.00 94.18  ? 7   GLU F C   1 
ATOM   11525 O  O   . GLU F 1 7   ? 18.019  22.907  51.485  1.00 54.73  ? 7   GLU F O   1 
ATOM   11526 C  CB  . GLU F 1 7   ? 18.693  19.662  50.334  1.00 70.84  ? 7   GLU F CB  1 
ATOM   11527 N  N   . PRO F 1 8   ? 20.207  22.521  51.682  1.00 99.55  ? 8   PRO F N   1 
ATOM   11528 C  CA  . PRO F 1 8   ? 20.831  23.377  50.646  1.00 75.50  ? 8   PRO F CA  1 
ATOM   11529 C  C   . PRO F 1 8   ? 21.242  22.393  49.529  1.00 61.70  ? 8   PRO F C   1 
ATOM   11530 O  O   . PRO F 1 8   ? 21.293  21.202  49.825  1.00 52.21  ? 8   PRO F O   1 
ATOM   11531 C  CB  . PRO F 1 8   ? 22.013  24.062  51.401  1.00 67.62  ? 8   PRO F CB  1 
ATOM   11532 C  CG  . PRO F 1 8   ? 21.914  23.603  52.872  1.00 70.30  ? 8   PRO F CG  1 
ATOM   11533 C  CD  . PRO F 1 8   ? 21.072  22.319  52.870  1.00 79.09  ? 8   PRO F CD  1 
ATOM   11534 N  N   . GLU F 1 9   ? 21.457  22.819  48.252  1.00 67.10  ? 9   GLU F N   1 
ATOM   11535 C  CA  . GLU F 1 9   ? 21.808  21.934  47.120  1.00 56.55  ? 9   GLU F CA  1 
ATOM   11536 C  C   . GLU F 1 9   ? 23.296  21.573  47.279  1.00 43.89  ? 9   GLU F C   1 
ATOM   11537 O  O   . GLU F 1 9   ? 24.167  22.459  47.253  1.00 40.84  ? 9   GLU F O   1 
ATOM   11538 C  CB  . GLU F 1 9   ? 21.415  22.409  45.687  1.00 42.00  ? 9   GLU F CB  1 
ATOM   11539 N  N   . PRO F 1 10  ? 23.674  20.292  47.513  1.00 35.66  ? 10  PRO F N   1 
ATOM   11540 C  CA  . PRO F 1 10  ? 25.081  19.888  47.388  1.00 35.02  ? 10  PRO F CA  1 
ATOM   11541 C  C   . PRO F 1 10  ? 25.543  19.881  45.931  1.00 29.43  ? 10  PRO F C   1 
ATOM   11542 O  O   . PRO F 1 10  ? 24.734  19.770  45.001  1.00 27.22  ? 10  PRO F O   1 
ATOM   11543 C  CB  . PRO F 1 10  ? 25.076  18.444  47.978  1.00 36.55  ? 10  PRO F CB  1 
ATOM   11544 C  CG  . PRO F 1 10  ? 23.707  17.899  47.627  1.00 37.65  ? 10  PRO F CG  1 
ATOM   11545 C  CD  . PRO F 1 10  ? 22.823  19.154  47.889  1.00 34.26  ? 10  PRO F CD  1 
ATOM   11546 N  N   . GLN F 1 11  ? 26.869  19.937  45.737  1.00 30.50  ? 11  GLN F N   1 
ATOM   11547 C  CA  . GLN F 1 11  ? 27.480  19.572  44.459  1.00 26.31  ? 11  GLN F CA  1 
ATOM   11548 C  C   . GLN F 1 11  ? 27.214  18.081  44.200  1.00 27.97  ? 11  GLN F C   1 
ATOM   11549 O  O   . GLN F 1 11  ? 26.718  17.363  45.067  1.00 28.42  ? 11  GLN F O   1 
ATOM   11550 C  CB  . GLN F 1 11  ? 28.967  19.863  44.540  1.00 26.24  ? 11  GLN F CB  1 
ATOM   11551 C  CG  . GLN F 1 11  ? 29.276  21.336  44.740  1.00 24.73  ? 11  GLN F CG  1 
ATOM   11552 C  CD  . GLN F 1 11  ? 30.741  21.605  44.501  1.00 27.53  ? 11  GLN F CD  1 
ATOM   11553 O  OE1 . GLN F 1 11  ? 31.303  21.436  43.404  1.00 23.64  ? 11  GLN F OE1 1 
ATOM   11554 N  NE2 . GLN F 1 11  ? 31.387  21.937  45.595  1.00 31.08  ? 11  GLN F NE2 1 
ATOM   11555 N  N   . MET F 1 12  ? 27.602  17.600  43.020  1.00 29.83  ? 12  MET F N   1 
ATOM   11556 C  CA  . MET F 1 12  ? 27.344  16.237  42.598  1.00 31.75  ? 12  MET F CA  1 
ATOM   11557 C  C   . MET F 1 12  ? 28.378  15.272  43.166  1.00 28.34  ? 12  MET F C   1 
ATOM   11558 O  O   . MET F 1 12  ? 29.024  14.519  42.431  1.00 30.05  ? 12  MET F O   1 
ATOM   11559 C  CB  . MET F 1 12  ? 27.351  16.133  41.064  1.00 41.51  ? 12  MET F CB  1 
ATOM   11560 C  CG  . MET F 1 12  ? 26.577  14.917  40.544  1.00 53.38  ? 12  MET F CG  1 
ATOM   11561 S  SD  . MET F 1 12  ? 24.811  15.244  40.733  1.00 63.96  ? 12  MET F SD  1 
ATOM   11562 C  CE  . MET F 1 12  ? 24.497  17.009  40.471  1.00 65.86  ? 12  MET F CE  1 
ATOM   11563 N  N   . VAL F 1 13  ? 28.476  15.246  44.478  1.00 25.30  ? 13  VAL F N   1 
ATOM   11564 C  CA  . VAL F 1 13  ? 29.394  14.348  45.153  1.00 27.83  ? 13  VAL F CA  1 
ATOM   11565 C  C   . VAL F 1 13  ? 28.981  12.903  44.899  1.00 31.65  ? 13  VAL F C   1 
ATOM   11566 O  O   . VAL F 1 13  ? 29.852  12.072  44.669  1.00 30.89  ? 13  VAL F O   1 
ATOM   11567 C  CB  . VAL F 1 13  ? 29.413  14.665  46.657  1.00 29.83  ? 13  VAL F CB  1 
ATOM   11568 C  CG1 . VAL F 1 13  ? 30.193  13.626  47.388  1.00 35.97  ? 13  VAL F CG1 1 
ATOM   11569 C  CG2 . VAL F 1 13  ? 29.970  16.055  46.937  1.00 32.49  ? 13  VAL F CG2 1 
ATOM   11570 N  N   . LEU F 1 14  ? 27.674  12.626  45.022  1.00 37.84  ? 14  LEU F N   1 
ATOM   11571 C  CA  . LEU F 1 14  ? 27.089  11.311  44.764  1.00 50.07  ? 14  LEU F CA  1 
ATOM   11572 C  C   . LEU F 1 14  ? 26.751  11.268  43.281  1.00 50.60  ? 14  LEU F C   1 
ATOM   11573 O  O   . LEU F 1 14  ? 25.717  11.691  42.837  1.00 57.46  ? 14  LEU F O   1 
ATOM   11574 C  CB  . LEU F 1 14  ? 25.878  11.004  45.645  1.00 52.73  ? 14  LEU F CB  1 
ATOM   11575 C  CG  . LEU F 1 14  ? 26.003  11.523  47.093  1.00 60.81  ? 14  LEU F CG  1 
ATOM   11576 C  CD1 . LEU F 1 14  ? 24.752  11.957  47.857  1.00 70.67  ? 14  LEU F CD1 1 
ATOM   11577 C  CD2 . LEU F 1 14  ? 26.636  10.482  47.902  1.00 64.73  ? 14  LEU F CD2 1 
ATOM   11578 N  N   . SER F 1 15  ? 27.692  10.842  42.472  1.00 59.64  ? 15  SER F N   1 
ATOM   11579 C  CA  . SER F 1 15  ? 27.448  10.777  41.055  1.00 53.25  ? 15  SER F CA  1 
ATOM   11580 C  C   . SER F 1 15  ? 27.037  9.340   40.690  1.00 48.80  ? 15  SER F C   1 
ATOM   11581 O  O   . SER F 1 15  ? 27.478  8.332   41.259  1.00 41.21  ? 15  SER F O   1 
ATOM   11582 C  CB  . SER F 1 15  ? 28.689  11.325  40.332  1.00 52.67  ? 15  SER F CB  1 
ATOM   11583 O  OG  . SER F 1 15  ? 28.861  10.836  38.997  1.00 53.07  ? 15  SER F OG  1 
ATOM   11584 N  N   . PRO F 1 16  ? 26.155  9.180   39.685  1.00 63.82  ? 16  PRO F N   1 
ATOM   11585 C  CA  . PRO F 1 16  ? 26.093  7.915   38.943  1.00 57.69  ? 16  PRO F CA  1 
ATOM   11586 C  C   . PRO F 1 16  ? 27.504  7.400   38.685  1.00 61.67  ? 16  PRO F C   1 
ATOM   11587 O  O   . PRO F 1 16  ? 28.464  8.178   38.683  1.00 69.98  ? 16  PRO F O   1 
ATOM   11588 C  CB  . PRO F 1 16  ? 25.465  8.301   37.581  1.00 62.99  ? 16  PRO F CB  1 
ATOM   11589 C  CG  . PRO F 1 16  ? 25.208  9.828   37.654  1.00 73.23  ? 16  PRO F CG  1 
ATOM   11590 C  CD  . PRO F 1 16  ? 25.289  10.240  39.120  1.00 66.30  ? 16  PRO F CD  1 
ATOM   11591 N  N   . LEU F 1 17  ? 27.606  6.106   38.379  1.00 54.59  ? 17  LEU F N   1 
ATOM   11592 C  CA  . LEU F 1 17  ? 28.842  5.513   37.908  1.00 56.05  ? 17  LEU F CA  1 
ATOM   11593 C  C   . LEU F 1 17  ? 29.235  6.170   36.574  1.00 52.60  ? 17  LEU F C   1 
ATOM   11594 O  O   . LEU F 1 17  ? 28.383  6.444   35.710  1.00 49.75  ? 17  LEU F O   1 
ATOM   11595 C  CB  . LEU F 1 17  ? 28.792  3.979   37.852  1.00 64.16  ? 17  LEU F CB  1 
ATOM   11596 C  CG  . LEU F 1 17  ? 28.845  3.218   39.203  1.00 73.86  ? 17  LEU F CG  1 
ATOM   11597 C  CD1 . LEU F 1 17  ? 29.038  1.691   38.904  1.00 71.26  ? 17  LEU F CD1 1 
ATOM   11598 C  CD2 . LEU F 1 17  ? 29.854  3.694   40.319  1.00 63.66  ? 17  LEU F CD2 1 
ATOM   11599 N  N   . THR F 1 18  ? 30.530  6.530   36.513  1.00 36.86  ? 18  THR F N   1 
ATOM   11600 C  CA  . THR F 1 18  ? 31.107  7.257   35.420  1.00 31.77  ? 18  THR F CA  1 
ATOM   11601 C  C   . THR F 1 18  ? 32.384  6.493   35.084  1.00 32.28  ? 18  THR F C   1 
ATOM   11602 O  O   . THR F 1 18  ? 33.101  6.008   35.958  1.00 32.00  ? 18  THR F O   1 
ATOM   11603 C  CB  . THR F 1 18  ? 31.376  8.738   35.741  1.00 29.95  ? 18  THR F CB  1 
ATOM   11604 O  OG1 . THR F 1 18  ? 32.196  8.838   36.887  1.00 34.59  ? 18  THR F OG1 1 
ATOM   11605 C  CG2 . THR F 1 18  ? 30.159  9.620   35.949  1.00 29.83  ? 18  THR F CG2 1 
ATOM   11606 N  N   . SER F 1 19  ? 32.727  6.487   33.806  1.00 29.46  ? 19  SER F N   1 
ATOM   11607 C  CA  . SER F 1 19  ? 33.838  5.693   33.360  1.00 35.14  ? 19  SER F CA  1 
ATOM   11608 C  C   . SER F 1 19  ? 35.027  6.576   32.991  1.00 25.50  ? 19  SER F C   1 
ATOM   11609 O  O   . SER F 1 19  ? 36.102  6.018   32.731  1.00 27.29  ? 19  SER F O   1 
ATOM   11610 C  CB  . SER F 1 19  ? 33.369  4.804   32.227  1.00 35.77  ? 19  SER F CB  1 
ATOM   11611 O  OG  . SER F 1 19  ? 32.506  5.607   31.433  1.00 44.22  ? 19  SER F OG  1 
ATOM   11612 N  N   . ALA F 1 20  ? 34.903  7.909   33.104  1.00 23.07  ? 20  ALA F N   1 
ATOM   11613 C  CA  . ALA F 1 20  ? 36.063  8.759   32.886  1.00 20.91  ? 20  ALA F CA  1 
ATOM   11614 C  C   . ALA F 1 20  ? 36.135  9.853   33.916  1.00 20.13  ? 20  ALA F C   1 
ATOM   11615 O  O   . ALA F 1 20  ? 35.123  10.289  34.392  1.00 20.75  ? 20  ALA F O   1 
ATOM   11616 C  CB  . ALA F 1 20  ? 36.025  9.309   31.475  1.00 23.13  ? 20  ALA F CB  1 
ATOM   11617 N  N   . ALA F 1 21  ? 37.352  10.323  34.212  1.00 20.76  ? 21  ALA F N   1 
ATOM   11618 C  CA  . ALA F 1 21  ? 37.522  11.443  35.124  1.00 19.19  ? 21  ALA F CA  1 
ATOM   11619 C  C   . ALA F 1 21  ? 38.760  12.216  34.736  1.00 20.60  ? 21  ALA F C   1 
ATOM   11620 O  O   . ALA F 1 21  ? 39.695  11.659  34.203  1.00 23.15  ? 21  ALA F O   1 
ATOM   11621 C  CB  . ALA F 1 21  ? 37.631  10.960  36.539  1.00 18.00  ? 21  ALA F CB  1 
ATOM   11622 N  N   . ILE F 1 22  ? 38.744  13.489  35.061  1.00 21.25  ? 22  ILE F N   1 
ATOM   11623 C  CA  . ILE F 1 22  ? 39.950  14.297  35.171  1.00 22.19  ? 22  ILE F CA  1 
ATOM   11624 C  C   . ILE F 1 22  ? 40.005  14.884  36.576  1.00 20.48  ? 22  ILE F C   1 
ATOM   11625 O  O   . ILE F 1 22  ? 39.044  15.463  37.086  1.00 20.44  ? 22  ILE F O   1 
ATOM   11626 C  CB  . ILE F 1 22  ? 39.987  15.404  34.107  1.00 24.41  ? 22  ILE F CB  1 
ATOM   11627 C  CG1 . ILE F 1 22  ? 40.161  14.806  32.718  1.00 26.98  ? 22  ILE F CG1 1 
ATOM   11628 C  CG2 . ILE F 1 22  ? 41.108  16.380  34.388  1.00 22.91  ? 22  ILE F CG2 1 
ATOM   11629 C  CD1 . ILE F 1 22  ? 40.167  15.808  31.585  1.00 24.82  ? 22  ILE F CD1 1 
ATOM   11630 N  N   . PHE F 1 23  ? 41.155  14.701  37.211  1.00 19.53  ? 23  PHE F N   1 
ATOM   11631 C  CA  . PHE F 1 23  ? 41.478  15.320  38.482  1.00 18.97  ? 23  PHE F CA  1 
ATOM   11632 C  C   . PHE F 1 23  ? 42.482  16.424  38.212  1.00 18.50  ? 23  PHE F C   1 
ATOM   11633 O  O   . PHE F 1 23  ? 43.537  16.179  37.675  1.00 18.13  ? 23  PHE F O   1 
ATOM   11634 C  CB  . PHE F 1 23  ? 42.103  14.326  39.455  1.00 18.63  ? 23  PHE F CB  1 
ATOM   11635 C  CG  . PHE F 1 23  ? 41.234  13.109  39.712  1.00 21.27  ? 23  PHE F CG  1 
ATOM   11636 C  CD1 . PHE F 1 23  ? 40.309  13.086  40.745  1.00 22.71  ? 23  PHE F CD1 1 
ATOM   11637 C  CD2 . PHE F 1 23  ? 41.370  11.968  38.925  1.00 21.78  ? 23  PHE F CD2 1 
ATOM   11638 C  CE1 . PHE F 1 23  ? 39.497  11.975  40.947  1.00 23.29  ? 23  PHE F CE1 1 
ATOM   11639 C  CE2 . PHE F 1 23  ? 40.603  10.858  39.176  1.00 22.31  ? 23  PHE F CE2 1 
ATOM   11640 C  CZ  . PHE F 1 23  ? 39.654  10.864  40.186  1.00 20.21  ? 23  PHE F CZ  1 
ATOM   11641 N  N   . LEU F 1 24  ? 42.121  17.639  38.550  1.00 20.15  ? 24  LEU F N   1 
ATOM   11642 C  CA  . LEU F 1 24  ? 42.991  18.782  38.372  1.00 21.96  ? 24  LEU F CA  1 
ATOM   11643 C  C   . LEU F 1 24  ? 43.230  19.435  39.729  1.00 19.85  ? 24  LEU F C   1 
ATOM   11644 O  O   . LEU F 1 24  ? 42.303  19.777  40.461  1.00 22.41  ? 24  LEU F O   1 
ATOM   11645 C  CB  . LEU F 1 24  ? 42.195  19.650  37.416  1.00 26.99  ? 24  LEU F CB  1 
ATOM   11646 C  CG  . LEU F 1 24  ? 42.921  20.747  36.662  1.00 33.85  ? 24  LEU F CG  1 
ATOM   11647 C  CD1 . LEU F 1 24  ? 44.051  20.212  35.799  1.00 46.24  ? 24  LEU F CD1 1 
ATOM   11648 C  CD2 . LEU F 1 24  ? 41.807  21.258  35.815  1.00 39.19  ? 24  LEU F CD2 1 
ATOM   11649 N  N   . VAL F 1 25  ? 44.490  19.544  40.125  1.00 20.53  ? 25  VAL F N   1 
ATOM   11650 C  CA  . VAL F 1 25  ? 44.867  20.231  41.349  1.00 20.65  ? 25  VAL F CA  1 
ATOM   11651 C  C   . VAL F 1 25  ? 45.748  21.416  40.983  1.00 19.44  ? 25  VAL F C   1 
ATOM   11652 O  O   . VAL F 1 25  ? 46.750  21.247  40.363  1.00 21.83  ? 25  VAL F O   1 
ATOM   11653 C  CB  . VAL F 1 25  ? 45.601  19.304  42.309  1.00 21.85  ? 25  VAL F CB  1 
ATOM   11654 C  CG1 . VAL F 1 25  ? 45.935  20.029  43.597  1.00 24.16  ? 25  VAL F CG1 1 
ATOM   11655 C  CG2 . VAL F 1 25  ? 44.773  18.085  42.642  1.00 22.79  ? 25  VAL F CG2 1 
ATOM   11656 N  N   . VAL F 1 26  ? 45.366  22.604  41.412  1.00 21.98  ? 26  VAL F N   1 
ATOM   11657 C  CA  . VAL F 1 26  ? 46.120  23.806  41.171  1.00 23.41  ? 26  VAL F CA  1 
ATOM   11658 C  C   . VAL F 1 26  ? 46.372  24.540  42.476  1.00 24.17  ? 26  VAL F C   1 
ATOM   11659 O  O   . VAL F 1 26  ? 45.607  24.377  43.447  1.00 21.89  ? 26  VAL F O   1 
ATOM   11660 C  CB  . VAL F 1 26  ? 45.395  24.713  40.146  1.00 24.79  ? 26  VAL F CB  1 
ATOM   11661 C  CG1 . VAL F 1 26  ? 45.126  23.936  38.843  1.00 27.54  ? 26  VAL F CG1 1 
ATOM   11662 C  CG2 . VAL F 1 26  ? 44.130  25.304  40.701  1.00 23.33  ? 26  VAL F CG2 1 
ATOM   11663 N  N   . THR F 1 27  ? 47.423  25.407  42.451  1.00 24.55  ? 27  THR F N   1 
ATOM   11664 C  CA  . THR F 1 27  ? 47.601  26.429  43.499  1.00 23.01  ? 27  THR F CA  1 
ATOM   11665 C  C   . THR F 1 27  ? 47.287  27.811  42.957  1.00 23.38  ? 27  THR F C   1 
ATOM   11666 O  O   . THR F 1 27  ? 47.417  28.076  41.764  1.00 25.28  ? 27  THR F O   1 
ATOM   11667 C  CB  . THR F 1 27  ? 48.987  26.346  44.096  1.00 22.09  ? 27  THR F CB  1 
ATOM   11668 O  OG1 . THR F 1 27  ? 49.928  26.378  43.055  1.00 22.15  ? 27  THR F OG1 1 
ATOM   11669 C  CG2 . THR F 1 27  ? 49.210  25.013  44.756  1.00 25.44  ? 27  THR F CG2 1 
ATOM   11670 N  N   . ILE F 1 28  ? 46.798  28.661  43.846  1.00 24.87  ? 28  ILE F N   1 
ATOM   11671 C  CA  . ILE F 1 28  ? 46.495  30.052  43.537  1.00 28.09  ? 28  ILE F CA  1 
ATOM   11672 C  C   . ILE F 1 28  ? 47.747  30.951  43.711  1.00 32.17  ? 28  ILE F C   1 
ATOM   11673 O  O   . ILE F 1 28  ? 48.348  31.111  44.788  1.00 26.72  ? 28  ILE F O   1 
ATOM   11674 C  CB  . ILE F 1 28  ? 45.351  30.548  44.431  1.00 26.85  ? 28  ILE F CB  1 
ATOM   11675 C  CG1 . ILE F 1 28  ? 44.158  29.680  44.370  1.00 28.54  ? 28  ILE F CG1 1 
ATOM   11676 C  CG2 . ILE F 1 28  ? 44.989  31.951  44.005  1.00 25.64  ? 28  ILE F CG2 1 
ATOM   11677 C  CD1 . ILE F 1 28  ? 43.137  29.993  45.443  1.00 33.19  ? 28  ILE F CD1 1 
ATOM   11678 N  N   . ASP F 1 29  ? 48.152  31.570  42.608  1.00 29.96  ? 29  ASP F N   1 
ATOM   11679 C  CA  . ASP F 1 29  ? 49.270  32.479  42.603  1.00 30.99  ? 29  ASP F CA  1 
ATOM   11680 C  C   . ASP F 1 29  ? 48.912  33.737  43.384  1.00 36.36  ? 29  ASP F C   1 
ATOM   11681 O  O   . ASP F 1 29  ? 47.746  34.052  43.606  1.00 39.49  ? 29  ASP F O   1 
ATOM   11682 C  CB  . ASP F 1 29  ? 49.595  32.902  41.184  1.00 34.02  ? 29  ASP F CB  1 
ATOM   11683 C  CG  . ASP F 1 29  ? 50.059  31.768  40.299  1.00 33.96  ? 29  ASP F CG  1 
ATOM   11684 O  OD1 . ASP F 1 29  ? 50.200  30.604  40.822  1.00 34.52  ? 29  ASP F OD1 1 
ATOM   11685 O  OD2 . ASP F 1 29  ? 50.274  32.103  39.117  1.00 46.08  ? 29  ASP F OD2 1 
ATOM   11686 N  N   . SER F 1 30  ? 49.919  34.488  43.842  1.00 39.70  ? 30  SER F N   1 
ATOM   11687 C  CA  . SER F 1 30  ? 49.534  35.572  44.716  1.00 38.51  ? 30  SER F CA  1 
ATOM   11688 C  C   . SER F 1 30  ? 48.963  36.633  43.792  1.00 33.68  ? 30  SER F C   1 
ATOM   11689 O  O   . SER F 1 30  ? 49.319  36.711  42.625  1.00 31.06  ? 30  SER F O   1 
ATOM   11690 C  CB  . SER F 1 30  ? 50.650  35.989  45.613  1.00 48.30  ? 30  SER F CB  1 
ATOM   11691 O  OG  . SER F 1 30  ? 51.148  37.199  45.113  1.00 64.18  ? 30  SER F OG  1 
ATOM   11692 N  N   . GLY F 1 31  ? 47.896  37.279  44.234  1.00 38.23  ? 31  GLY F N   1 
ATOM   11693 C  CA  . GLY F 1 31  ? 47.212  38.236  43.384  1.00 30.41  ? 31  GLY F CA  1 
ATOM   11694 C  C   . GLY F 1 31  ? 46.085  37.585  42.612  1.00 33.55  ? 31  GLY F C   1 
ATOM   11695 O  O   . GLY F 1 31  ? 45.319  38.309  42.046  1.00 36.21  ? 31  GLY F O   1 
ATOM   11696 N  N   . GLY F 1 32  ? 45.964  36.243  42.593  1.00 39.23  ? 32  GLY F N   1 
ATOM   11697 C  CA  . GLY F 1 32  ? 44.996  35.547  41.737  1.00 34.92  ? 32  GLY F CA  1 
ATOM   11698 C  C   . GLY F 1 32  ? 43.595  35.380  42.366  1.00 33.04  ? 32  GLY F C   1 
ATOM   11699 O  O   . GLY F 1 32  ? 42.694  34.804  41.768  1.00 28.07  ? 32  GLY F O   1 
ATOM   11700 N  N   . GLU F 1 33  ? 43.392  35.855  43.603  1.00 33.60  ? 33  GLU F N   1 
ATOM   11701 C  CA  . GLU F 1 33  ? 42.213  35.479  44.364  1.00 28.18  ? 33  GLU F CA  1 
ATOM   11702 C  C   . GLU F 1 33  ? 40.937  36.015  43.707  1.00 29.51  ? 33  GLU F C   1 
ATOM   11703 O  O   . GLU F 1 33  ? 39.900  35.395  43.825  1.00 27.85  ? 33  GLU F O   1 
ATOM   11704 C  CB  . GLU F 1 33  ? 42.357  35.992  45.790  1.00 27.68  ? 33  GLU F CB  1 
ATOM   11705 C  CG  . GLU F 1 33  ? 43.458  35.335  46.626  1.00 30.63  ? 33  GLU F CG  1 
ATOM   11706 C  CD  . GLU F 1 33  ? 44.836  35.945  46.523  1.00 35.63  ? 33  GLU F CD  1 
ATOM   11707 O  OE1 . GLU F 1 33  ? 45.008  36.891  45.733  1.00 34.09  ? 33  GLU F OE1 1 
ATOM   11708 O  OE2 . GLU F 1 33  ? 45.724  35.499  47.283  1.00 41.01  ? 33  GLU F OE2 1 
ATOM   11709 N  N   . ASP F 1 34  ? 40.937  37.209  43.100  1.00 30.63  ? 34  ASP F N   1 
ATOM   11710 C  CA  . ASP F 1 34  ? 39.701  37.746  42.515  1.00 33.65  ? 34  ASP F CA  1 
ATOM   11711 C  C   . ASP F 1 34  ? 39.301  36.904  41.289  1.00 35.31  ? 34  ASP F C   1 
ATOM   11712 O  O   . ASP F 1 34  ? 38.133  36.604  41.096  1.00 30.84  ? 34  ASP F O   1 
ATOM   11713 C  CB  . ASP F 1 34  ? 39.828  39.150  41.917  1.00 39.09  ? 34  ASP F CB  1 
ATOM   11714 C  CG  . ASP F 1 34  ? 40.022  40.279  42.906  1.00 51.00  ? 34  ASP F CG  1 
ATOM   11715 O  OD1 . ASP F 1 34  ? 39.639  40.089  44.080  1.00 51.70  ? 34  ASP F OD1 1 
ATOM   11716 O  OD2 . ASP F 1 34  ? 40.614  41.298  42.504  1.00 55.48  ? 34  ASP F OD2 1 
ATOM   11717 N  N   . THR F 1 35  ? 40.278  36.571  40.430  1.00 31.59  ? 35  THR F N   1 
ATOM   11718 C  CA  . THR F 1 35  ? 40.010  35.732  39.294  1.00 30.03  ? 35  THR F CA  1 
ATOM   11719 C  C   . THR F 1 35  ? 39.383  34.421  39.743  1.00 30.48  ? 35  THR F C   1 
ATOM   11720 O  O   . THR F 1 35  ? 38.419  33.980  39.132  1.00 29.35  ? 35  THR F O   1 
ATOM   11721 C  CB  . THR F 1 35  ? 41.290  35.444  38.521  1.00 29.60  ? 35  THR F CB  1 
ATOM   11722 O  OG1 . THR F 1 35  ? 41.826  36.702  38.150  1.00 29.17  ? 35  THR F OG1 1 
ATOM   11723 C  CG2 . THR F 1 35  ? 40.988  34.640  37.273  1.00 29.53  ? 35  THR F CG2 1 
ATOM   11724 N  N   . VAL F 1 36  ? 39.956  33.797  40.771  1.00 27.70  ? 36  VAL F N   1 
ATOM   11725 C  CA  . VAL F 1 36  ? 39.437  32.541  41.286  1.00 29.69  ? 36  VAL F CA  1 
ATOM   11726 C  C   . VAL F 1 36  ? 38.007  32.712  41.807  1.00 28.43  ? 36  VAL F C   1 
ATOM   11727 O  O   . VAL F 1 36  ? 37.128  31.940  41.504  1.00 28.07  ? 36  VAL F O   1 
ATOM   11728 C  CB  . VAL F 1 36  ? 40.357  31.954  42.370  1.00 30.80  ? 36  VAL F CB  1 
ATOM   11729 C  CG1 . VAL F 1 36  ? 39.714  30.767  43.066  1.00 27.90  ? 36  VAL F CG1 1 
ATOM   11730 C  CG2 . VAL F 1 36  ? 41.698  31.555  41.761  1.00 33.43  ? 36  VAL F CG2 1 
ATOM   11731 N  N   . ARG F 1 37  ? 37.732  33.745  42.560  1.00 27.33  ? 37  ARG F N   1 
ATOM   11732 C  CA  . ARG F 1 37  ? 36.389  33.933  43.059  1.00 33.67  ? 37  ARG F CA  1 
ATOM   11733 C  C   . ARG F 1 37  ? 35.383  34.076  41.928  1.00 30.08  ? 37  ARG F C   1 
ATOM   11734 O  O   . ARG F 1 37  ? 34.289  33.568  42.071  1.00 32.54  ? 37  ARG F O   1 
ATOM   11735 C  CB  . ARG F 1 37  ? 36.223  35.215  43.895  1.00 38.55  ? 37  ARG F CB  1 
ATOM   11736 C  CG  . ARG F 1 37  ? 36.572  35.051  45.359  1.00 42.33  ? 37  ARG F CG  1 
ATOM   11737 C  CD  . ARG F 1 37  ? 35.946  36.173  46.191  1.00 55.03  ? 37  ARG F CD  1 
ATOM   11738 N  NE  . ARG F 1 37  ? 37.023  36.427  47.149  1.00 56.71  ? 37  ARG F NE  1 
ATOM   11739 C  CZ  . ARG F 1 37  ? 38.196  37.052  46.937  1.00 52.71  ? 37  ARG F CZ  1 
ATOM   11740 N  NH1 . ARG F 1 37  ? 38.397  37.871  45.916  1.00 59.15  ? 37  ARG F NH1 1 
ATOM   11741 N  NH2 . ARG F 1 37  ? 39.158  36.938  47.831  1.00 50.14  ? 37  ARG F NH2 1 
ATOM   11742 N  N   . ASP F 1 38  ? 35.722  34.790  40.852  1.00 29.37  ? 38  ASP F N   1 
ATOM   11743 C  CA  . ASP F 1 38  ? 34.843  34.866  39.684  1.00 38.65  ? 38  ASP F CA  1 
ATOM   11744 C  C   . ASP F 1 38  ? 34.564  33.492  39.099  1.00 30.39  ? 38  ASP F C   1 
ATOM   11745 O  O   . ASP F 1 38  ? 33.427  33.201  38.763  1.00 27.65  ? 38  ASP F O   1 
ATOM   11746 C  CB  . ASP F 1 38  ? 35.354  35.627  38.467  1.00 43.38  ? 38  ASP F CB  1 
ATOM   11747 C  CG  . ASP F 1 38  ? 35.267  37.125  38.558  1.00 50.74  ? 38  ASP F CG  1 
ATOM   11748 O  OD1 . ASP F 1 38  ? 34.548  37.630  39.444  1.00 48.35  ? 38  ASP F OD1 1 
ATOM   11749 O  OD2 . ASP F 1 38  ? 35.959  37.751  37.760  1.00 82.55  ? 38  ASP F OD2 1 
ATOM   11750 N  N   . LEU F 1 39  ? 35.611  32.687  38.927  1.00 29.40  ? 39  LEU F N   1 
ATOM   11751 C  CA  . LEU F 1 39  ? 35.436  31.375  38.323  1.00 26.81  ? 39  LEU F CA  1 
ATOM   11752 C  C   . LEU F 1 39  ? 34.562  30.477  39.206  1.00 29.60  ? 39  LEU F C   1 
ATOM   11753 O  O   . LEU F 1 39  ? 33.729  29.709  38.715  1.00 27.53  ? 39  LEU F O   1 
ATOM   11754 C  CB  . LEU F 1 39  ? 36.840  30.829  38.103  1.00 27.48  ? 39  LEU F CB  1 
ATOM   11755 C  CG  . LEU F 1 39  ? 36.948  29.473  37.430  1.00 29.43  ? 39  LEU F CG  1 
ATOM   11756 C  CD1 . LEU F 1 39  ? 36.694  28.347  38.366  1.00 28.39  ? 39  LEU F CD1 1 
ATOM   11757 C  CD2 . LEU F 1 39  ? 35.976  29.444  36.259  1.00 35.23  ? 39  LEU F CD2 1 
ATOM   11758 N  N   . LEU F 1 40  ? 34.722  30.551  40.535  1.00 28.98  ? 40  LEU F N   1 
ATOM   11759 C  CA  . LEU F 1 40  ? 33.921  29.697  41.401  1.00 24.14  ? 40  LEU F CA  1 
ATOM   11760 C  C   . LEU F 1 40  ? 32.450  30.034  41.238  1.00 25.47  ? 40  LEU F C   1 
ATOM   11761 O  O   . LEU F 1 40  ? 31.570  29.189  41.368  1.00 28.63  ? 40  LEU F O   1 
ATOM   11762 C  CB  . LEU F 1 40  ? 34.394  29.879  42.831  1.00 26.75  ? 40  LEU F CB  1 
ATOM   11763 C  CG  . LEU F 1 40  ? 35.811  29.386  43.143  1.00 28.19  ? 40  LEU F CG  1 
ATOM   11764 C  CD1 . LEU F 1 40  ? 36.160  29.613  44.564  1.00 28.70  ? 40  LEU F CD1 1 
ATOM   11765 C  CD2 . LEU F 1 40  ? 35.887  27.934  42.862  1.00 30.25  ? 40  LEU F CD2 1 
ATOM   11766 N  N   . SER F 1 41  ? 32.139  31.297  41.007  1.00 25.22  ? 41  SER F N   1 
ATOM   11767 C  CA  . SER F 1 41  ? 30.734  31.658  40.930  1.00 32.07  ? 41  SER F CA  1 
ATOM   11768 C  C   . SER F 1 41  ? 30.129  31.227  39.582  1.00 34.53  ? 41  SER F C   1 
ATOM   11769 O  O   . SER F 1 41  ? 28.924  31.152  39.449  1.00 33.41  ? 41  SER F O   1 
ATOM   11770 C  CB  . SER F 1 41  ? 30.476  33.138  41.192  1.00 31.00  ? 41  SER F CB  1 
ATOM   11771 O  OG  . SER F 1 41  ? 30.934  33.895  40.090  1.00 30.74  ? 41  SER F OG  1 
ATOM   11772 N  N   . ASP F 1 42  ? 30.950  30.917  38.584  1.00 29.83  ? 42  ASP F N   1 
ATOM   11773 C  CA  . ASP F 1 42  ? 30.453  30.516  37.279  1.00 29.86  ? 42  ASP F CA  1 
ATOM   11774 C  C   . ASP F 1 42  ? 30.644  29.027  36.960  1.00 29.47  ? 42  ASP F C   1 
ATOM   11775 O  O   . ASP F 1 42  ? 30.225  28.588  35.890  1.00 25.17  ? 42  ASP F O   1 
ATOM   11776 C  CB  . ASP F 1 42  ? 31.196  31.285  36.215  1.00 26.74  ? 42  ASP F CB  1 
ATOM   11777 C  CG  . ASP F 1 42  ? 30.826  32.734  36.021  1.00 30.05  ? 42  ASP F CG  1 
ATOM   11778 O  OD1 . ASP F 1 42  ? 29.739  33.172  36.371  1.00 44.54  ? 42  ASP F OD1 1 
ATOM   11779 O  OD2 . ASP F 1 42  ? 31.652  33.428  35.498  1.00 36.42  ? 42  ASP F OD2 1 
ATOM   11780 N  N   . VAL F 1 43  ? 31.253  28.247  37.872  1.00 26.18  ? 43  VAL F N   1 
ATOM   11781 C  CA  . VAL F 1 43  ? 31.656  26.897  37.528  1.00 25.73  ? 43  VAL F CA  1 
ATOM   11782 C  C   . VAL F 1 43  ? 30.412  26.030  37.290  1.00 26.55  ? 43  VAL F C   1 
ATOM   11783 O  O   . VAL F 1 43  ? 30.444  25.190  36.375  1.00 27.84  ? 43  VAL F O   1 
ATOM   11784 C  CB  . VAL F 1 43  ? 32.674  26.303  38.530  1.00 27.50  ? 43  VAL F CB  1 
ATOM   11785 C  CG1 . VAL F 1 43  ? 31.990  25.971  39.803  1.00 31.84  ? 43  VAL F CG1 1 
ATOM   11786 C  CG2 . VAL F 1 43  ? 33.322  25.012  38.085  1.00 28.27  ? 43  VAL F CG2 1 
ATOM   11787 N  N   . ALA F 1 44  ? 29.287  26.280  37.996  1.00 21.61  ? 44  ALA F N   1 
ATOM   11788 C  CA  . ALA F 1 44  ? 28.074  25.513  37.731  1.00 21.35  ? 44  ALA F CA  1 
ATOM   11789 C  C   . ALA F 1 44  ? 27.546  25.836  36.334  1.00 25.33  ? 44  ALA F C   1 
ATOM   11790 O  O   . ALA F 1 44  ? 27.076  24.952  35.598  1.00 26.56  ? 44  ALA F O   1 
ATOM   11791 C  CB  . ALA F 1 44  ? 27.011  25.802  38.748  1.00 21.47  ? 44  ALA F CB  1 
ATOM   11792 N  N   . SER F 1 45  ? 27.637  27.112  35.917  1.00 26.60  ? 45  SER F N   1 
ATOM   11793 C  CA  . SER F 1 45  ? 27.060  27.404  34.610  1.00 28.05  ? 45  SER F CA  1 
ATOM   11794 C  C   . SER F 1 45  ? 27.935  26.829  33.502  1.00 26.83  ? 45  SER F C   1 
ATOM   11795 O  O   . SER F 1 45  ? 27.401  26.484  32.451  1.00 25.91  ? 45  SER F O   1 
ATOM   11796 C  CB  . SER F 1 45  ? 26.659  28.835  34.394  1.00 28.04  ? 45  SER F CB  1 
ATOM   11797 O  OG  . SER F 1 45  ? 27.743  29.676  34.654  1.00 32.54  ? 45  SER F OG  1 
ATOM   11798 N  N   . LEU F 1 46  ? 29.253  26.716  33.727  1.00 24.57  ? 46  LEU F N   1 
ATOM   11799 C  CA  . LEU F 1 46  ? 30.131  26.089  32.742  1.00 22.21  ? 46  LEU F CA  1 
ATOM   11800 C  C   . LEU F 1 46  ? 29.836  24.592  32.621  1.00 22.05  ? 46  LEU F C   1 
ATOM   11801 O  O   . LEU F 1 46  ? 29.899  24.006  31.539  1.00 23.84  ? 46  LEU F O   1 
ATOM   11802 C  CB  . LEU F 1 46  ? 31.574  26.380  33.125  1.00 20.83  ? 46  LEU F CB  1 
ATOM   11803 C  CG  . LEU F 1 46  ? 31.932  27.849  32.947  1.00 23.55  ? 46  LEU F CG  1 
ATOM   11804 C  CD1 . LEU F 1 46  ? 33.347  28.149  33.397  1.00 28.40  ? 46  LEU F CD1 1 
ATOM   11805 C  CD2 . LEU F 1 46  ? 31.777  28.322  31.497  1.00 26.49  ? 46  LEU F CD2 1 
ATOM   11806 N  N   . GLU F 1 47  ? 29.522  23.952  33.747  1.00 24.81  ? 47  GLU F N   1 
ATOM   11807 C  CA  . GLU F 1 47  ? 29.194  22.539  33.755  1.00 24.83  ? 47  GLU F CA  1 
ATOM   11808 C  C   . GLU F 1 47  ? 27.946  22.354  32.872  1.00 28.77  ? 47  GLU F C   1 
ATOM   11809 O  O   . GLU F 1 47  ? 27.869  21.424  32.072  1.00 23.87  ? 47  GLU F O   1 
ATOM   11810 C  CB  . GLU F 1 47  ? 29.004  22.113  35.198  1.00 25.78  ? 47  GLU F CB  1 
ATOM   11811 C  CG  . GLU F 1 47  ? 28.687  20.646  35.381  1.00 29.58  ? 47  GLU F CG  1 
ATOM   11812 C  CD  . GLU F 1 47  ? 28.163  20.334  36.756  1.00 37.35  ? 47  GLU F CD  1 
ATOM   11813 O  OE1 . GLU F 1 47  ? 28.915  20.111  37.651  1.00 36.98  ? 47  GLU F OE1 1 
ATOM   11814 O  OE2 . GLU F 1 47  ? 26.982  20.301  36.982  1.00 57.73  ? 47  GLU F OE2 1 
ATOM   11815 N  N   . ARG F 1 48  ? 26.955  23.239  32.994  1.00 25.53  ? 48  ARG F N   1 
ATOM   11816 C  CA  . ARG F 1 48  ? 25.788  23.097  32.152  1.00 25.51  ? 48  ARG F CA  1 
ATOM   11817 C  C   . ARG F 1 48  ? 26.067  23.439  30.699  1.00 24.90  ? 48  ARG F C   1 
ATOM   11818 O  O   . ARG F 1 48  ? 25.597  22.749  29.829  1.00 26.06  ? 48  ARG F O   1 
ATOM   11819 C  CB  . ARG F 1 48  ? 24.670  24.018  32.636  1.00 31.08  ? 48  ARG F CB  1 
ATOM   11820 C  CG  . ARG F 1 48  ? 24.157  23.487  33.952  1.00 28.42  ? 48  ARG F CG  1 
ATOM   11821 C  CD  . ARG F 1 48  ? 22.828  24.144  34.174  1.00 35.34  ? 48  ARG F CD  1 
ATOM   11822 N  NE  . ARG F 1 48  ? 22.884  25.587  34.429  1.00 38.10  ? 48  ARG F NE  1 
ATOM   11823 C  CZ  . ARG F 1 48  ? 23.273  26.198  35.549  1.00 34.99  ? 48  ARG F CZ  1 
ATOM   11824 N  NH1 . ARG F 1 48  ? 23.540  25.503  36.630  1.00 41.36  ? 48  ARG F NH1 1 
ATOM   11825 N  NH2 . ARG F 1 48  ? 23.457  27.507  35.546  1.00 33.27  ? 48  ARG F NH2 1 
ATOM   11826 N  N   . ALA F 1 49  ? 26.783  24.526  30.408  1.00 24.84  ? 49  ALA F N   1 
ATOM   11827 C  CA  . ALA F 1 49  ? 27.117  24.835  29.026  1.00 24.56  ? 49  ALA F CA  1 
ATOM   11828 C  C   . ALA F 1 49  ? 27.810  23.652  28.323  1.00 22.90  ? 49  ALA F C   1 
ATOM   11829 O  O   . ALA F 1 49  ? 27.502  23.325  27.207  1.00 26.34  ? 49  ALA F O   1 
ATOM   11830 C  CB  . ALA F 1 49  ? 28.022  26.011  29.024  1.00 29.04  ? 49  ALA F CB  1 
ATOM   11831 N  N   . VAL F 1 50  ? 28.789  23.000  28.937  1.00 20.33  ? 50  VAL F N   1 
ATOM   11832 C  CA  . VAL F 1 50  ? 29.473  21.911  28.287  1.00 21.52  ? 50  VAL F CA  1 
ATOM   11833 C  C   . VAL F 1 50  ? 28.602  20.664  28.290  1.00 25.55  ? 50  VAL F C   1 
ATOM   11834 O  O   . VAL F 1 50  ? 28.609  19.932  27.321  1.00 24.11  ? 50  VAL F O   1 
ATOM   11835 C  CB  . VAL F 1 50  ? 30.839  21.605  28.915  1.00 24.97  ? 50  VAL F CB  1 
ATOM   11836 C  CG1 . VAL F 1 50  ? 31.490  20.338  28.315  1.00 25.76  ? 50  VAL F CG1 1 
ATOM   11837 C  CG2 . VAL F 1 50  ? 31.753  22.818  28.854  1.00 24.32  ? 50  VAL F CG2 1 
ATOM   11838 N  N   . GLY F 1 51  ? 27.818  20.432  29.351  1.00 25.10  ? 51  GLY F N   1 
ATOM   11839 C  CA  . GLY F 1 51  ? 27.232  19.111  29.516  1.00 27.34  ? 51  GLY F CA  1 
ATOM   11840 C  C   . GLY F 1 51  ? 25.789  19.024  28.988  1.00 31.65  ? 51  GLY F C   1 
ATOM   11841 O  O   . GLY F 1 51  ? 25.322  17.956  28.630  1.00 27.72  ? 51  GLY F O   1 
ATOM   11842 N  N   . PHE F 1 52  ? 25.029  20.120  28.960  1.00 24.36  ? 52  PHE F N   1 
ATOM   11843 C  CA  . PHE F 1 52  ? 23.629  20.016  28.621  1.00 28.35  ? 52  PHE F CA  1 
ATOM   11844 C  C   . PHE F 1 52  ? 23.427  19.365  27.244  1.00 32.71  ? 52  PHE F C   1 
ATOM   11845 O  O   . PHE F 1 52  ? 22.599  18.465  27.105  1.00 35.02  ? 52  PHE F O   1 
ATOM   11846 C  CB  . PHE F 1 52  ? 23.003  21.409  28.729  1.00 30.67  ? 52  PHE F CB  1 
ATOM   11847 C  CG  . PHE F 1 52  ? 21.546  21.284  28.374  1.00 32.36  ? 52  PHE F CG  1 
ATOM   11848 C  CD1 . PHE F 1 52  ? 20.640  20.673  29.250  1.00 34.32  ? 52  PHE F CD1 1 
ATOM   11849 C  CD2 . PHE F 1 52  ? 21.116  21.679  27.129  1.00 31.55  ? 52  PHE F CD2 1 
ATOM   11850 C  CE1 . PHE F 1 52  ? 19.339  20.433  28.864  1.00 33.74  ? 52  PHE F CE1 1 
ATOM   11851 C  CE2 . PHE F 1 52  ? 19.799  21.489  26.787  1.00 33.04  ? 52  PHE F CE2 1 
ATOM   11852 C  CZ  . PHE F 1 52  ? 18.917  20.872  27.655  1.00 33.79  ? 52  PHE F CZ  1 
ATOM   11853 N  N   . ARG F 1 53  ? 24.220  19.776  26.247  1.00 33.50  ? 53  ARG F N   1 
ATOM   11854 C  CA  . ARG F 1 53  ? 24.048  19.319  24.881  1.00 33.07  ? 53  ARG F CA  1 
ATOM   11855 C  C   . ARG F 1 53  ? 24.310  17.819  24.772  1.00 35.36  ? 53  ARG F C   1 
ATOM   11856 O  O   . ARG F 1 53  ? 24.030  17.243  23.721  1.00 36.36  ? 53  ARG F O   1 
ATOM   11857 C  CB  . ARG F 1 53  ? 24.853  20.122  23.834  1.00 37.89  ? 53  ARG F CB  1 
ATOM   11858 C  CG  . ARG F 1 53  ? 26.381  20.117  23.820  1.00 44.73  ? 53  ARG F CG  1 
ATOM   11859 C  CD  . ARG F 1 53  ? 27.069  20.751  22.548  1.00 51.85  ? 53  ARG F CD  1 
ATOM   11860 N  NE  . ARG F 1 53  ? 28.431  21.285  22.758  1.00 46.99  ? 53  ARG F NE  1 
ATOM   11861 C  CZ  . ARG F 1 53  ? 28.633  22.127  23.779  1.00 54.62  ? 53  ARG F CZ  1 
ATOM   11862 N  NH1 . ARG F 1 53  ? 27.583  22.635  24.349  1.00 73.84  ? 53  ARG F NH1 1 
ATOM   11863 N  NH2 . ARG F 1 53  ? 29.801  22.515  24.267  1.00 55.39  ? 53  ARG F NH2 1 
ATOM   11864 N  N   . ALA F 1 54  ? 24.875  17.185  25.804  1.00 32.14  ? 54  ALA F N   1 
ATOM   11865 C  CA  . ALA F 1 54  ? 25.236  15.781  25.724  1.00 30.20  ? 54  ALA F CA  1 
ATOM   11866 C  C   . ALA F 1 54  ? 24.337  14.950  26.603  1.00 32.74  ? 54  ALA F C   1 
ATOM   11867 O  O   . ALA F 1 54  ? 24.627  13.773  26.804  1.00 44.71  ? 54  ALA F O   1 
ATOM   11868 C  CB  . ALA F 1 54  ? 26.677  15.555  26.127  1.00 31.71  ? 54  ALA F CB  1 
ATOM   11869 N  N   . GLN F 1 55  ? 23.244  15.527  27.075  1.00 39.42  ? 55  GLN F N   1 
ATOM   11870 C  CA  . GLN F 1 55  ? 22.283  14.789  27.887  1.00 51.84  ? 55  GLN F CA  1 
ATOM   11871 C  C   . GLN F 1 55  ? 21.561  13.740  27.050  1.00 52.49  ? 55  GLN F C   1 
ATOM   11872 O  O   . GLN F 1 55  ? 21.437  13.879  25.852  1.00 65.23  ? 55  GLN F O   1 
ATOM   11873 C  CB  . GLN F 1 55  ? 21.233  15.679  28.570  1.00 67.61  ? 55  GLN F CB  1 
ATOM   11874 C  CG  . GLN F 1 55  ? 21.766  16.545  29.712  1.00 74.98  ? 55  GLN F CG  1 
ATOM   11875 C  CD  . GLN F 1 55  ? 22.473  15.826  30.864  1.00 82.57  ? 55  GLN F CD  1 
ATOM   11876 O  OE1 . GLN F 1 55  ? 23.184  14.796  30.789  1.00 65.82  ? 55  GLN F OE1 1 
ATOM   11877 N  NE2 . GLN F 1 55  ? 22.330  16.478  32.000  1.00 88.50  ? 55  GLN F NE2 1 
ATOM   11878 N  N   . PRO F 1 56  ? 21.097  12.630  27.670  1.00 69.99  ? 56  PRO F N   1 
ATOM   11879 C  CA  . PRO F 1 56  ? 21.337  12.391  29.108  1.00 65.08  ? 56  PRO F CA  1 
ATOM   11880 C  C   . PRO F 1 56  ? 22.527  11.465  29.435  1.00 53.86  ? 56  PRO F C   1 
ATOM   11881 O  O   . PRO F 1 56  ? 22.926  11.389  30.586  1.00 53.89  ? 56  PRO F O   1 
ATOM   11882 C  CB  . PRO F 1 56  ? 19.947  11.867  29.532  1.00 58.10  ? 56  PRO F CB  1 
ATOM   11883 C  CG  . PRO F 1 56  ? 19.385  11.235  28.237  1.00 59.13  ? 56  PRO F CG  1 
ATOM   11884 C  CD  . PRO F 1 56  ? 20.311  11.555  27.037  1.00 59.72  ? 56  PRO F CD  1 
ATOM   11885 N  N   . ASP F 1 57  ? 23.128  10.851  28.394  1.00 53.45  ? 57  ASP F N   1 
ATOM   11886 C  CA  . ASP F 1 57  ? 24.227  9.909   28.495  1.00 61.75  ? 57  ASP F CA  1 
ATOM   11887 C  C   . ASP F 1 57  ? 25.530  10.491  29.020  1.00 55.55  ? 57  ASP F C   1 
ATOM   11888 O  O   . ASP F 1 57  ? 26.364  9.706   29.489  1.00 53.88  ? 57  ASP F O   1 
ATOM   11889 C  CB  . ASP F 1 57  ? 24.732  9.520   27.121  1.00 72.52  ? 57  ASP F CB  1 
ATOM   11890 C  CG  . ASP F 1 57  ? 23.706  8.734   26.343  1.00 78.86  ? 57  ASP F CG  1 
ATOM   11891 O  OD1 . ASP F 1 57  ? 22.608  8.500   26.916  1.00 69.10  ? 57  ASP F OD1 1 
ATOM   11892 O  OD2 . ASP F 1 57  ? 24.044  8.334   25.206  1.00 73.11  ? 57  ASP F OD2 1 
ATOM   11893 N  N   . GLY F 1 58  ? 25.744  11.811  28.847  1.00 39.49  ? 58  GLY F N   1 
ATOM   11894 C  CA  . GLY F 1 58  ? 27.039  12.415  29.138  1.00 34.73  ? 58  GLY F CA  1 
ATOM   11895 C  C   . GLY F 1 58  ? 27.408  12.343  30.621  1.00 30.84  ? 58  GLY F C   1 
ATOM   11896 O  O   . GLY F 1 58  ? 28.557  12.018  30.944  1.00 29.46  ? 58  GLY F O   1 
ATOM   11897 N  N   . ARG F 1 59  ? 26.446  12.707  31.484  1.00 29.33  ? 59  ARG F N   1 
ATOM   11898 C  CA  . ARG F 1 59  ? 26.577  12.591  32.913  1.00 32.77  ? 59  ARG F CA  1 
ATOM   11899 C  C   . ARG F 1 59  ? 27.836  13.333  33.397  1.00 31.33  ? 59  ARG F C   1 
ATOM   11900 O  O   . ARG F 1 59  ? 28.542  12.887  34.312  1.00 30.36  ? 59  ARG F O   1 
ATOM   11901 C  CB  . ARG F 1 59  ? 26.648  11.105  33.285  1.00 40.39  ? 59  ARG F CB  1 
ATOM   11902 C  CG  . ARG F 1 59  ? 25.311  10.382  33.233  1.00 49.93  ? 59  ARG F CG  1 
ATOM   11903 C  CD  . ARG F 1 59  ? 25.346  8.905   32.728  1.00 59.72  ? 59  ARG F CD  1 
ATOM   11904 N  NE  . ARG F 1 59  ? 25.401  7.794   33.696  1.00 51.98  ? 59  ARG F NE  1 
ATOM   11905 N  N   . LEU F 1 60  ? 28.126  14.462  32.786  1.00 24.32  ? 60  LEU F N   1 
ATOM   11906 C  CA  . LEU F 1 60  ? 29.222  15.306  33.197  1.00 25.02  ? 60  LEU F CA  1 
ATOM   11907 C  C   . LEU F 1 60  ? 28.897  15.997  34.526  1.00 26.25  ? 60  LEU F C   1 
ATOM   11908 O  O   . LEU F 1 60  ? 27.851  16.632  34.678  1.00 25.07  ? 60  LEU F O   1 
ATOM   11909 C  CB  . LEU F 1 60  ? 29.438  16.350  32.098  1.00 25.23  ? 60  LEU F CB  1 
ATOM   11910 C  CG  . LEU F 1 60  ? 30.446  17.462  32.398  1.00 22.64  ? 60  LEU F CG  1 
ATOM   11911 C  CD1 . LEU F 1 60  ? 31.804  16.870  32.332  1.00 24.35  ? 60  LEU F CD1 1 
ATOM   11912 C  CD2 . LEU F 1 60  ? 30.388  18.564  31.419  1.00 24.95  ? 60  LEU F CD2 1 
ATOM   11913 N  N   . SER F 1 61  ? 29.816  15.932  35.484  1.00 23.60  ? 61  SER F N   1 
ATOM   11914 C  CA  . SER F 1 61  ? 29.704  16.737  36.686  1.00 24.25  ? 61  SER F CA  1 
ATOM   11915 C  C   . SER F 1 61  ? 31.101  17.226  37.058  1.00 21.65  ? 61  SER F C   1 
ATOM   11916 O  O   . SER F 1 61  ? 32.100  16.630  36.645  1.00 21.91  ? 61  SER F O   1 
ATOM   11917 C  CB  . SER F 1 61  ? 29.089  15.986  37.846  1.00 23.68  ? 61  SER F CB  1 
ATOM   11918 O  OG  . SER F 1 61  ? 29.827  14.803  38.175  1.00 25.73  ? 61  SER F OG  1 
ATOM   11919 N  N   . CYS F 1 62  ? 31.129  18.314  37.821  1.00 21.32  ? 62  CYS F N   1 
ATOM   11920 C  CA  . CYS F 1 62  ? 32.363  18.894  38.337  1.00 25.55  ? 62  CYS F CA  1 
ATOM   11921 C  C   . CYS F 1 62  ? 32.184  19.139  39.827  1.00 23.60  ? 62  CYS F C   1 
ATOM   11922 O  O   . CYS F 1 62  ? 31.237  19.804  40.204  1.00 25.50  ? 62  CYS F O   1 
ATOM   11923 C  CB  . CYS F 1 62  ? 32.697  20.238  37.687  1.00 25.64  ? 62  CYS F CB  1 
ATOM   11924 S  SG  . CYS F 1 62  ? 34.256  20.868  38.332  1.00 27.00  ? 62  CYS F SG  1 
ATOM   11925 N  N   . VAL F 1 63  ? 33.014  18.558  40.681  1.00 24.48  ? 63  VAL F N   1 
ATOM   11926 C  CA  . VAL F 1 63  ? 32.975  18.921  42.101  1.00 21.06  ? 63  VAL F CA  1 
ATOM   11927 C  C   . VAL F 1 63  ? 34.221  19.768  42.376  1.00 22.39  ? 63  VAL F C   1 
ATOM   11928 O  O   . VAL F 1 63  ? 35.345  19.403  42.000  1.00 22.07  ? 63  VAL F O   1 
ATOM   11929 C  CB  . VAL F 1 63  ? 32.965  17.660  43.000  1.00 20.66  ? 63  VAL F CB  1 
ATOM   11930 C  CG1 . VAL F 1 63  ? 33.020  18.016  44.461  1.00 21.28  ? 63  VAL F CG1 1 
ATOM   11931 C  CG2 . VAL F 1 63  ? 31.734  16.827  42.711  1.00 21.13  ? 63  VAL F CG2 1 
ATOM   11932 N  N   . THR F 1 64  ? 34.006  20.944  42.981  1.00 21.60  ? 64  THR F N   1 
ATOM   11933 C  CA  . THR F 1 64  ? 35.069  21.900  43.239  1.00 19.80  ? 64  THR F CA  1 
ATOM   11934 C  C   . THR F 1 64  ? 35.344  21.899  44.710  1.00 19.19  ? 64  THR F C   1 
ATOM   11935 O  O   . THR F 1 64  ? 34.427  22.014  45.487  1.00 22.45  ? 64  THR F O   1 
ATOM   11936 C  CB  . THR F 1 64  ? 34.604  23.300  42.900  1.00 21.58  ? 64  THR F CB  1 
ATOM   11937 O  OG1 . THR F 1 64  ? 34.334  23.309  41.525  1.00 21.01  ? 64  THR F OG1 1 
ATOM   11938 C  CG2 . THR F 1 64  ? 35.692  24.309  43.057  1.00 23.33  ? 64  THR F CG2 1 
ATOM   11939 N  N   . GLY F 1 65  ? 36.616  21.762  45.054  1.00 23.04  ? 65  GLY F N   1 
ATOM   11940 C  CA  . GLY F 1 65  ? 37.115  21.678  46.428  1.00 22.08  ? 65  GLY F CA  1 
ATOM   11941 C  C   . GLY F 1 65  ? 38.135  22.766  46.705  1.00 20.84  ? 65  GLY F C   1 
ATOM   11942 O  O   . GLY F 1 65  ? 38.956  23.100  45.857  1.00 23.62  ? 65  GLY F O   1 
ATOM   11943 N  N   . ILE F 1 66  ? 38.107  23.284  47.921  1.00 23.35  ? 66  ILE F N   1 
ATOM   11944 C  CA  . ILE F 1 66  ? 39.019  24.351  48.327  1.00 23.91  ? 66  ILE F CA  1 
ATOM   11945 C  C   . ILE F 1 66  ? 39.816  23.874  49.525  1.00 21.55  ? 66  ILE F C   1 
ATOM   11946 O  O   . ILE F 1 66  ? 39.265  23.298  50.436  1.00 24.06  ? 66  ILE F O   1 
ATOM   11947 C  CB  . ILE F 1 66  ? 38.177  25.598  48.614  1.00 22.60  ? 66  ILE F CB  1 
ATOM   11948 C  CG1 . ILE F 1 66  ? 37.426  25.966  47.407  1.00 25.49  ? 66  ILE F CG1 1 
ATOM   11949 C  CG2 . ILE F 1 66  ? 39.058  26.751  49.059  1.00 22.75  ? 66  ILE F CG2 1 
ATOM   11950 C  CD1 . ILE F 1 66  ? 36.122  26.642  47.684  1.00 28.95  ? 66  ILE F CD1 1 
ATOM   11951 N  N   . GLY F 1 67  ? 41.113  24.097  49.486  1.00 22.59  ? 67  GLY F N   1 
ATOM   11952 C  CA  . GLY F 1 67  ? 42.029  23.776  50.585  1.00 27.66  ? 67  GLY F CA  1 
ATOM   11953 C  C   . GLY F 1 67  ? 41.916  24.740  51.786  1.00 25.93  ? 67  GLY F C   1 
ATOM   11954 O  O   . GLY F 1 67  ? 41.353  25.829  51.727  1.00 24.44  ? 67  GLY F O   1 
ATOM   11955 N  N   . SER F 1 68  ? 42.517  24.318  52.885  1.00 27.69  ? 68  SER F N   1 
ATOM   11956 C  CA  . SER F 1 68  ? 42.564  25.096  54.106  1.00 29.18  ? 68  SER F CA  1 
ATOM   11957 C  C   . SER F 1 68  ? 43.222  26.474  53.918  1.00 27.67  ? 68  SER F C   1 
ATOM   11958 O  O   . SER F 1 68  ? 42.611  27.489  54.269  1.00 25.46  ? 68  SER F O   1 
ATOM   11959 C  CB  . SER F 1 68  ? 43.274  24.264  55.199  1.00 32.98  ? 68  SER F CB  1 
ATOM   11960 O  OG  . SER F 1 68  ? 43.092  24.843  56.481  1.00 33.10  ? 68  SER F OG  1 
ATOM   11961 N  N   . GLU F 1 69  ? 44.450  26.534  53.397  1.00 26.40  ? 69  GLU F N   1 
ATOM   11962 C  CA  . GLU F 1 69  ? 45.102  27.825  53.276  1.00 29.88  ? 69  GLU F CA  1 
ATOM   11963 C  C   . GLU F 1 69  ? 44.422  28.711  52.245  1.00 31.43  ? 69  GLU F C   1 
ATOM   11964 O  O   . GLU F 1 69  ? 44.325  29.941  52.426  1.00 29.89  ? 69  GLU F O   1 
ATOM   11965 C  CB  . GLU F 1 69  ? 46.540  27.651  52.820  1.00 36.17  ? 69  GLU F CB  1 
ATOM   11966 C  CG  . GLU F 1 69  ? 47.382  26.859  53.832  1.00 55.87  ? 69  GLU F CG  1 
ATOM   11967 C  CD  . GLU F 1 69  ? 48.900  26.826  53.580  1.00 51.83  ? 69  GLU F CD  1 
ATOM   11968 O  OE1 . GLU F 1 69  ? 49.476  26.004  54.294  1.00 53.73  ? 69  GLU F OE1 1 
ATOM   11969 O  OE2 . GLU F 1 69  ? 49.472  27.602  52.746  1.00 46.06  ? 69  GLU F OE2 1 
ATOM   11970 N  N   . ALA F 1 70  ? 43.936  28.090  51.165  1.00 27.47  ? 70  ALA F N   1 
ATOM   11971 C  CA  . ALA F 1 70  ? 43.219  28.869  50.164  1.00 25.52  ? 70  ALA F CA  1 
ATOM   11972 C  C   . ALA F 1 70  ? 41.946  29.470  50.720  1.00 21.00  ? 70  ALA F C   1 
ATOM   11973 O  O   . ALA F 1 70  ? 41.540  30.561  50.340  1.00 20.34  ? 70  ALA F O   1 
ATOM   11974 C  CB  . ALA F 1 70  ? 42.913  27.960  48.992  1.00 29.67  ? 70  ALA F CB  1 
ATOM   11975 N  N   . TRP F 1 71  ? 41.272  28.708  51.587  1.00 21.79  ? 71  TRP F N   1 
ATOM   11976 C  CA  . TRP F 1 71  ? 40.023  29.153  52.171  1.00 25.06  ? 71  TRP F CA  1 
ATOM   11977 C  C   . TRP F 1 71  ? 40.192  30.527  52.822  1.00 26.63  ? 71  TRP F C   1 
ATOM   11978 O  O   . TRP F 1 71  ? 39.362  31.424  52.657  1.00 27.00  ? 71  TRP F O   1 
ATOM   11979 C  CB  . TRP F 1 71  ? 39.500  28.123  53.204  1.00 28.18  ? 71  TRP F CB  1 
ATOM   11980 C  CG  . TRP F 1 71  ? 38.111  28.483  53.629  1.00 26.29  ? 71  TRP F CG  1 
ATOM   11981 C  CD1 . TRP F 1 71  ? 37.749  29.462  54.499  1.00 28.62  ? 71  TRP F CD1 1 
ATOM   11982 C  CD2 . TRP F 1 71  ? 36.891  27.987  53.063  1.00 28.73  ? 71  TRP F CD2 1 
ATOM   11983 N  NE1 . TRP F 1 71  ? 36.388  29.566  54.566  1.00 27.33  ? 71  TRP F NE1 1 
ATOM   11984 C  CE2 . TRP F 1 71  ? 35.835  28.687  53.696  1.00 28.48  ? 71  TRP F CE2 1 
ATOM   11985 C  CE3 . TRP F 1 71  ? 36.594  27.004  52.113  1.00 33.92  ? 71  TRP F CE3 1 
ATOM   11986 C  CZ2 . TRP F 1 71  ? 34.508  28.438  53.415  1.00 30.95  ? 71  TRP F CZ2 1 
ATOM   11987 C  CZ3 . TRP F 1 71  ? 35.274  26.781  51.815  1.00 33.48  ? 71  TRP F CZ3 1 
ATOM   11988 C  CH2 . TRP F 1 71  ? 34.256  27.521  52.420  1.00 34.75  ? 71  TRP F CH2 1 
ATOM   11989 N  N   . ASP F 1 72  ? 41.286  30.642  53.589  1.00 32.41  ? 72  ASP F N   1 
ATOM   11990 C  CA  . ASP F 1 72  ? 41.663  31.809  54.366  1.00 33.46  ? 72  ASP F CA  1 
ATOM   11991 C  C   . ASP F 1 72  ? 41.953  32.972  53.424  1.00 30.30  ? 72  ASP F C   1 
ATOM   11992 O  O   . ASP F 1 72  ? 41.580  34.099  53.740  1.00 28.06  ? 72  ASP F O   1 
ATOM   11993 C  CB  . ASP F 1 72  ? 42.922  31.498  55.163  1.00 32.20  ? 72  ASP F CB  1 
ATOM   11994 C  CG  . ASP F 1 72  ? 42.718  30.541  56.320  1.00 32.74  ? 72  ASP F CG  1 
ATOM   11995 O  OD1 . ASP F 1 72  ? 41.541  30.479  56.774  1.00 28.18  ? 72  ASP F OD1 1 
ATOM   11996 O  OD2 . ASP F 1 72  ? 43.743  29.891  56.716  1.00 33.12  ? 72  ASP F OD2 1 
ATOM   11997 N  N   . ARG F 1 73  ? 42.597  32.705  52.269  1.00 29.39  ? 73  ARG F N   1 
ATOM   11998 C  CA  . ARG F 1 73  ? 42.846  33.813  51.333  1.00 28.06  ? 73  ARG F CA  1 
ATOM   11999 C  C   . ARG F 1 73  ? 41.584  34.252  50.592  1.00 29.68  ? 73  ARG F C   1 
ATOM   12000 O  O   . ARG F 1 73  ? 41.531  35.369  50.141  1.00 31.80  ? 73  ARG F O   1 
ATOM   12001 C  CB  . ARG F 1 73  ? 43.910  33.501  50.282  1.00 29.58  ? 73  ARG F CB  1 
ATOM   12002 C  CG  . ARG F 1 73  ? 45.209  32.975  50.884  1.00 28.98  ? 73  ARG F CG  1 
ATOM   12003 C  CD  . ARG F 1 73  ? 46.081  32.169  49.932  1.00 26.91  ? 73  ARG F CD  1 
ATOM   12004 N  NE  . ARG F 1 73  ? 46.391  32.923  48.713  1.00 24.23  ? 73  ARG F NE  1 
ATOM   12005 C  CZ  . ARG F 1 73  ? 47.040  32.409  47.680  1.00 23.90  ? 73  ARG F CZ  1 
ATOM   12006 N  NH1 . ARG F 1 73  ? 47.313  31.112  47.688  1.00 27.30  ? 73  ARG F NH1 1 
ATOM   12007 N  NH2 . ARG F 1 73  ? 47.337  33.152  46.608  1.00 25.69  ? 73  ARG F NH2 1 
ATOM   12008 N  N   . LEU F 1 74  ? 40.600  33.352  50.387  1.00 31.79  ? 74  LEU F N   1 
ATOM   12009 C  CA  . LEU F 1 74  ? 39.515  33.635  49.468  1.00 29.84  ? 74  LEU F CA  1 
ATOM   12010 C  C   . LEU F 1 74  ? 38.302  34.230  50.162  1.00 30.67  ? 74  LEU F C   1 
ATOM   12011 O  O   . LEU F 1 74  ? 37.603  34.957  49.502  1.00 28.47  ? 74  LEU F O   1 
ATOM   12012 C  CB  . LEU F 1 74  ? 39.096  32.360  48.767  1.00 32.58  ? 74  LEU F CB  1 
ATOM   12013 C  CG  . LEU F 1 74  ? 40.048  31.866  47.676  1.00 33.61  ? 74  LEU F CG  1 
ATOM   12014 C  CD1 . LEU F 1 74  ? 39.601  30.517  47.105  1.00 36.06  ? 74  LEU F CD1 1 
ATOM   12015 C  CD2 . LEU F 1 74  ? 40.079  32.841  46.556  1.00 31.62  ? 74  LEU F CD2 1 
ATOM   12016 N  N   . PHE F 1 75  ? 38.017  33.825  51.410  1.00 35.51  ? 75  PHE F N   1 
ATOM   12017 C  CA  . PHE F 1 75  ? 36.737  34.108  52.047  1.00 38.60  ? 75  PHE F CA  1 
ATOM   12018 C  C   . PHE F 1 75  ? 36.811  34.803  53.408  1.00 44.57  ? 75  PHE F C   1 
ATOM   12019 O  O   . PHE F 1 75  ? 37.690  34.499  54.219  1.00 40.56  ? 75  PHE F O   1 
ATOM   12020 C  CB  . PHE F 1 75  ? 36.025  32.783  52.255  1.00 39.02  ? 75  PHE F CB  1 
ATOM   12021 C  CG  . PHE F 1 75  ? 35.810  32.023  50.967  1.00 37.73  ? 75  PHE F CG  1 
ATOM   12022 C  CD1 . PHE F 1 75  ? 35.200  32.631  49.877  1.00 37.11  ? 75  PHE F CD1 1 
ATOM   12023 C  CD2 . PHE F 1 75  ? 36.282  30.727  50.849  1.00 41.31  ? 75  PHE F CD2 1 
ATOM   12024 C  CE1 . PHE F 1 75  ? 35.035  31.954  48.693  1.00 43.65  ? 75  PHE F CE1 1 
ATOM   12025 C  CE2 . PHE F 1 75  ? 36.135  30.047  49.656  1.00 47.01  ? 75  PHE F CE2 1 
ATOM   12026 C  CZ  . PHE F 1 75  ? 35.520  30.662  48.572  1.00 49.24  ? 75  PHE F CZ  1 
ATOM   12027 N  N   . SER F 1 76  ? 35.811  35.712  53.581  1.00 67.68  ? 76  SER F N   1 
ATOM   12028 C  CA  . SER F 1 76  ? 35.498  36.555  54.738  1.00 59.63  ? 76  SER F CA  1 
ATOM   12029 C  C   . SER F 1 76  ? 35.241  35.710  55.994  1.00 54.72  ? 76  SER F C   1 
ATOM   12030 O  O   . SER F 1 76  ? 35.966  35.737  56.981  1.00 46.32  ? 76  SER F O   1 
ATOM   12031 C  CB  . SER F 1 76  ? 34.265  37.416  54.408  1.00 43.95  ? 76  SER F CB  1 
ATOM   12032 N  N   . GLY F 1 77  ? 34.207  34.882  55.966  1.00 52.51  ? 77  GLY F N   1 
ATOM   12033 C  CA  . GLY F 1 77  ? 33.541  34.579  57.225  1.00 52.76  ? 77  GLY F CA  1 
ATOM   12034 C  C   . GLY F 1 77  ? 34.184  33.460  58.034  1.00 41.34  ? 77  GLY F C   1 
ATOM   12035 O  O   . GLY F 1 77  ? 35.388  33.385  58.161  1.00 30.67  ? 77  GLY F O   1 
ATOM   12036 N  N   . ALA F 1 78  ? 33.326  32.590  58.567  1.00 42.25  ? 78  ALA F N   1 
ATOM   12037 C  CA  . ALA F 1 78  ? 33.751  31.372  59.240  1.00 45.18  ? 78  ALA F CA  1 
ATOM   12038 C  C   . ALA F 1 78  ? 34.233  30.309  58.256  1.00 41.16  ? 78  ALA F C   1 
ATOM   12039 O  O   . ALA F 1 78  ? 33.979  30.391  57.063  1.00 39.69  ? 78  ALA F O   1 
ATOM   12040 C  CB  . ALA F 1 78  ? 32.660  30.789  60.081  1.00 45.34  ? 78  ALA F CB  1 
ATOM   12041 N  N   . ARG F 1 79  ? 35.065  29.439  58.834  1.00 35.49  ? 79  ARG F N   1 
ATOM   12042 C  CA  . ARG F 1 79  ? 35.703  28.301  58.242  1.00 31.73  ? 79  ARG F CA  1 
ATOM   12043 C  C   . ARG F 1 79  ? 34.862  27.063  58.527  1.00 35.98  ? 79  ARG F C   1 
ATOM   12044 O  O   . ARG F 1 79  ? 34.326  26.936  59.617  1.00 32.04  ? 79  ARG F O   1 
ATOM   12045 C  CB  . ARG F 1 79  ? 37.045  28.049  58.942  1.00 33.32  ? 79  ARG F CB  1 
ATOM   12046 C  CG  . ARG F 1 79  ? 38.059  28.999  58.351  1.00 33.26  ? 79  ARG F CG  1 
ATOM   12047 C  CD  . ARG F 1 79  ? 39.417  28.865  58.950  1.00 27.04  ? 79  ARG F CD  1 
ATOM   12048 N  NE  . ARG F 1 79  ? 39.810  27.472  58.932  1.00 30.04  ? 79  ARG F NE  1 
ATOM   12049 C  CZ  . ARG F 1 79  ? 40.648  26.940  58.053  1.00 41.44  ? 79  ARG F CZ  1 
ATOM   12050 N  NH1 . ARG F 1 79  ? 41.201  27.693  57.128  1.00 43.86  ? 79  ARG F NH1 1 
ATOM   12051 N  NH2 . ARG F 1 79  ? 40.965  25.638  58.047  1.00 39.58  ? 79  ARG F NH2 1 
ATOM   12052 N  N   . PRO F 1 80  ? 34.771  26.077  57.600  1.00 34.80  ? 80  PRO F N   1 
ATOM   12053 C  CA  . PRO F 1 80  ? 34.209  24.788  57.953  1.00 34.44  ? 80  PRO F CA  1 
ATOM   12054 C  C   . PRO F 1 80  ? 34.999  24.269  59.142  1.00 31.66  ? 80  PRO F C   1 
ATOM   12055 O  O   . PRO F 1 80  ? 36.223  24.332  59.136  1.00 30.00  ? 80  PRO F O   1 
ATOM   12056 C  CB  . PRO F 1 80  ? 34.436  23.955  56.683  1.00 37.88  ? 80  PRO F CB  1 
ATOM   12057 C  CG  . PRO F 1 80  ? 34.455  25.019  55.590  1.00 36.03  ? 80  PRO F CG  1 
ATOM   12058 C  CD  . PRO F 1 80  ? 35.193  26.162  56.195  1.00 33.87  ? 80  PRO F CD  1 
ATOM   12059 N  N   . ALA F 1 81  ? 34.278  23.666  60.093  1.00 32.06  ? 81  ALA F N   1 
ATOM   12060 C  CA  . ALA F 1 81  ? 34.852  23.104  61.307  1.00 30.33  ? 81  ALA F CA  1 
ATOM   12061 C  C   . ALA F 1 81  ? 36.008  22.138  61.069  1.00 27.62  ? 81  ALA F C   1 
ATOM   12062 O  O   . ALA F 1 81  ? 36.970  22.184  61.811  1.00 31.88  ? 81  ALA F O   1 
ATOM   12063 C  CB  . ALA F 1 81  ? 33.740  22.397  62.067  1.00 32.75  ? 81  ALA F CB  1 
ATOM   12064 N  N   . GLY F 1 82  ? 35.945  21.263  60.064  1.00 29.62  ? 82  GLY F N   1 
ATOM   12065 C  CA  . GLY F 1 82  ? 36.898  20.167  59.896  1.00 27.36  ? 82  GLY F CA  1 
ATOM   12066 C  C   . GLY F 1 82  ? 38.086  20.525  58.996  1.00 27.16  ? 82  GLY F C   1 
ATOM   12067 O  O   . GLY F 1 82  ? 38.986  19.723  58.800  1.00 27.97  ? 82  GLY F O   1 
ATOM   12068 N  N   . LEU F 1 83  ? 38.119  21.736  58.431  1.00 27.72  ? 83  LEU F N   1 
ATOM   12069 C  CA  . LEU F 1 83  ? 39.117  22.036  57.417  1.00 27.99  ? 83  LEU F CA  1 
ATOM   12070 C  C   . LEU F 1 83  ? 40.491  22.341  58.023  1.00 31.94  ? 83  LEU F C   1 
ATOM   12071 O  O   . LEU F 1 83  ? 40.672  23.254  58.798  1.00 36.13  ? 83  LEU F O   1 
ATOM   12072 C  CB  . LEU F 1 83  ? 38.586  23.171  56.535  1.00 27.09  ? 83  LEU F CB  1 
ATOM   12073 C  CG  . LEU F 1 83  ? 39.434  23.507  55.309  1.00 25.85  ? 83  LEU F CG  1 
ATOM   12074 C  CD1 . LEU F 1 83  ? 39.683  22.299  54.366  1.00 26.74  ? 83  LEU F CD1 1 
ATOM   12075 C  CD2 . LEU F 1 83  ? 38.759  24.638  54.567  1.00 28.49  ? 83  LEU F CD2 1 
ATOM   12076 N  N   . HIS F 1 84  ? 41.512  21.615  57.589  1.00 31.89  ? 84  HIS F N   1 
ATOM   12077 C  CA  . HIS F 1 84  ? 42.904  21.875  57.944  1.00 27.61  ? 84  HIS F CA  1 
ATOM   12078 C  C   . HIS F 1 84  ? 43.769  21.320  56.816  1.00 27.76  ? 84  HIS F C   1 
ATOM   12079 O  O   . HIS F 1 84  ? 43.290  20.654  55.900  1.00 29.86  ? 84  HIS F O   1 
ATOM   12080 C  CB  . HIS F 1 84  ? 43.244  21.163  59.263  1.00 25.04  ? 84  HIS F CB  1 
ATOM   12081 C  CG  . HIS F 1 84  ? 42.754  19.752  59.347  1.00 22.66  ? 84  HIS F CG  1 
ATOM   12082 N  ND1 . HIS F 1 84  ? 41.573  19.419  59.975  1.00 27.91  ? 84  HIS F ND1 1 
ATOM   12083 C  CD2 . HIS F 1 84  ? 43.277  18.607  58.904  1.00 24.51  ? 84  HIS F CD2 1 
ATOM   12084 C  CE1 . HIS F 1 84  ? 41.373  18.104  59.903  1.00 26.01  ? 84  HIS F CE1 1 
ATOM   12085 N  NE2 . HIS F 1 84  ? 42.410  17.589  59.247  1.00 23.80  ? 84  HIS F NE2 1 
ATOM   12086 N  N   . PRO F 1 85  ? 45.075  21.589  56.812  1.00 31.71  ? 85  PRO F N   1 
ATOM   12087 C  CA  . PRO F 1 85  ? 45.995  20.966  55.854  1.00 27.24  ? 85  PRO F CA  1 
ATOM   12088 C  C   . PRO F 1 85  ? 46.033  19.482  56.083  1.00 23.95  ? 85  PRO F C   1 
ATOM   12089 O  O   . PRO F 1 85  ? 45.876  19.035  57.183  1.00 25.59  ? 85  PRO F O   1 
ATOM   12090 C  CB  . PRO F 1 85  ? 47.348  21.612  56.187  1.00 28.99  ? 85  PRO F CB  1 
ATOM   12091 C  CG  . PRO F 1 85  ? 46.952  22.950  56.803  1.00 27.21  ? 85  PRO F CG  1 
ATOM   12092 C  CD  . PRO F 1 85  ? 45.748  22.573  57.678  1.00 27.95  ? 85  PRO F CD  1 
ATOM   12093 N  N   . PHE F 1 86  ? 46.169  18.725  55.007  1.00 26.46  ? 86  PHE F N   1 
ATOM   12094 C  CA  . PHE F 1 86  ? 46.399  17.303  55.098  1.00 25.86  ? 86  PHE F CA  1 
ATOM   12095 C  C   . PHE F 1 86  ? 47.627  17.082  55.979  1.00 31.13  ? 86  PHE F C   1 
ATOM   12096 O  O   . PHE F 1 86  ? 48.657  17.765  55.823  1.00 31.06  ? 86  PHE F O   1 
ATOM   12097 C  CB  . PHE F 1 86  ? 46.610  16.719  53.703  1.00 25.01  ? 86  PHE F CB  1 
ATOM   12098 C  CG  . PHE F 1 86  ? 46.926  15.225  53.627  1.00 25.97  ? 86  PHE F CG  1 
ATOM   12099 C  CD1 . PHE F 1 86  ? 48.213  14.728  53.781  1.00 24.34  ? 86  PHE F CD1 1 
ATOM   12100 C  CD2 . PHE F 1 86  ? 45.921  14.333  53.335  1.00 29.63  ? 86  PHE F CD2 1 
ATOM   12101 C  CE1 . PHE F 1 86  ? 48.460  13.374  53.674  1.00 27.19  ? 86  PHE F CE1 1 
ATOM   12102 C  CE2 . PHE F 1 86  ? 46.184  12.972  53.190  1.00 29.06  ? 86  PHE F CE2 1 
ATOM   12103 C  CZ  . PHE F 1 86  ? 47.444  12.492  53.366  1.00 27.34  ? 86  PHE F CZ  1 
ATOM   12104 N  N   . ARG F 1 87  ? 47.498  16.093  56.886  1.00 34.46  ? 87  ARG F N   1 
ATOM   12105 C  CA  . ARG F 1 87  ? 48.524  15.818  57.867  1.00 36.78  ? 87  ARG F CA  1 
ATOM   12106 C  C   . ARG F 1 87  ? 49.358  14.634  57.440  1.00 31.90  ? 87  ARG F C   1 
ATOM   12107 O  O   . ARG F 1 87  ? 48.839  13.516  57.328  1.00 35.33  ? 87  ARG F O   1 
ATOM   12108 C  CB  . ARG F 1 87  ? 47.889  15.417  59.193  1.00 44.11  ? 87  ARG F CB  1 
ATOM   12109 C  CG  . ARG F 1 87  ? 47.241  16.651  59.787  1.00 50.49  ? 87  ARG F CG  1 
ATOM   12110 C  CD  . ARG F 1 87  ? 46.336  16.196  60.858  1.00 53.98  ? 87  ARG F CD  1 
ATOM   12111 N  NE  . ARG F 1 87  ? 45.917  17.527  61.268  1.00 57.10  ? 87  ARG F NE  1 
ATOM   12112 C  CZ  . ARG F 1 87  ? 44.810  17.759  61.924  1.00 64.98  ? 87  ARG F CZ  1 
ATOM   12113 N  NH1 . ARG F 1 87  ? 43.936  16.789  62.196  1.00 66.61  ? 87  ARG F NH1 1 
ATOM   12114 N  NH2 . ARG F 1 87  ? 44.574  19.009  62.254  1.00 66.45  ? 87  ARG F NH2 1 
ATOM   12115 N  N   . GLU F 1 88  ? 50.649  14.911  57.285  1.00 30.18  ? 88  GLU F N   1 
ATOM   12116 C  CA  . GLU F 1 88  ? 51.639  13.923  56.914  1.00 34.38  ? 88  GLU F CA  1 
ATOM   12117 C  C   . GLU F 1 88  ? 51.560  12.787  57.926  1.00 29.85  ? 88  GLU F C   1 
ATOM   12118 O  O   . GLU F 1 88  ? 51.161  13.013  59.066  1.00 29.87  ? 88  GLU F O   1 
ATOM   12119 C  CB  . GLU F 1 88  ? 52.903  14.768  56.821  1.00 48.78  ? 88  GLU F CB  1 
ATOM   12120 C  CG  . GLU F 1 88  ? 54.169  13.959  56.501  1.00 72.90  ? 88  GLU F CG  1 
ATOM   12121 C  CD  . GLU F 1 88  ? 55.189  14.779  55.734  1.00 76.03  ? 88  GLU F CD  1 
ATOM   12122 O  OE1 . GLU F 1 88  ? 54.762  15.136  54.594  1.00 61.04  ? 88  GLU F OE1 1 
ATOM   12123 O  OE2 . GLU F 1 88  ? 56.315  15.093  56.240  1.00 79.75  ? 88  GLU F OE2 1 
ATOM   12124 N  N   . LEU F 1 89  ? 51.778  11.548  57.483  1.00 33.98  ? 89  LEU F N   1 
ATOM   12125 C  CA  . LEU F 1 89  ? 51.843  10.378  58.372  1.00 34.79  ? 89  LEU F CA  1 
ATOM   12126 C  C   . LEU F 1 89  ? 53.183  9.700   58.135  1.00 34.08  ? 89  LEU F C   1 
ATOM   12127 O  O   . LEU F 1 89  ? 53.480  9.303   57.000  1.00 36.24  ? 89  LEU F O   1 
ATOM   12128 C  CB  . LEU F 1 89  ? 50.701  9.356   58.215  1.00 36.63  ? 89  LEU F CB  1 
ATOM   12129 C  CG  . LEU F 1 89  ? 49.278  9.890   58.376  1.00 32.85  ? 89  LEU F CG  1 
ATOM   12130 C  CD1 . LEU F 1 89  ? 48.301  8.777   58.076  1.00 38.53  ? 89  LEU F CD1 1 
ATOM   12131 C  CD2 . LEU F 1 89  ? 49.043  10.445  59.717  1.00 30.79  ? 89  LEU F CD2 1 
ATOM   12132 N  N   . ASP F 1 90  ? 54.004  9.652   59.206  1.00 43.70  ? 90  ASP F N   1 
ATOM   12133 C  CA  . ASP F 1 90  ? 55.383  9.176   59.130  1.00 44.38  ? 90  ASP F CA  1 
ATOM   12134 C  C   . ASP F 1 90  ? 55.443  7.846   59.828  1.00 47.83  ? 90  ASP F C   1 
ATOM   12135 O  O   . ASP F 1 90  ? 55.607  7.780   61.026  1.00 50.82  ? 90  ASP F O   1 
ATOM   12136 C  CB  . ASP F 1 90  ? 56.416  10.123  59.696  1.00 49.22  ? 90  ASP F CB  1 
ATOM   12137 C  CG  . ASP F 1 90  ? 57.250  10.596  58.530  1.00 68.71  ? 90  ASP F CG  1 
ATOM   12138 O  OD1 . ASP F 1 90  ? 56.699  11.441  57.770  1.00 74.70  ? 90  ASP F OD1 1 
ATOM   12139 O  OD2 . ASP F 1 90  ? 58.328  9.977   58.288  1.00 69.53  ? 90  ASP F OD2 1 
ATOM   12140 N  N   . GLY F 1 91  ? 55.114  6.795   59.102  1.00 45.69  ? 91  GLY F N   1 
ATOM   12141 C  CA  . GLY F 1 91  ? 55.029  5.491   59.726  1.00 42.81  ? 91  GLY F CA  1 
ATOM   12142 C  C   . GLY F 1 91  ? 56.408  4.849   59.799  1.00 36.53  ? 91  GLY F C   1 
ATOM   12143 O  O   . GLY F 1 91  ? 57.359  5.223   59.134  1.00 35.18  ? 91  GLY F O   1 
ATOM   12144 N  N   . PRO F 1 92  ? 56.520  3.771   60.558  1.00 37.96  ? 92  PRO F N   1 
ATOM   12145 C  CA  . PRO F 1 92  ? 57.804  3.083   60.612  1.00 37.37  ? 92  PRO F CA  1 
ATOM   12146 C  C   . PRO F 1 92  ? 58.314  2.666   59.228  1.00 41.79  ? 92  PRO F C   1 
ATOM   12147 O  O   . PRO F 1 92  ? 59.520  2.693   59.033  1.00 37.12  ? 92  PRO F O   1 
ATOM   12148 C  CB  . PRO F 1 92  ? 57.552  1.894   61.590  1.00 41.08  ? 92  PRO F CB  1 
ATOM   12149 C  CG  . PRO F 1 92  ? 56.032  1.948   61.974  1.00 42.46  ? 92  PRO F CG  1 
ATOM   12150 C  CD  . PRO F 1 92  ? 55.405  3.183   61.347  1.00 39.74  ? 92  PRO F CD  1 
ATOM   12151 N  N   . VAL F 1 93  ? 57.445  2.267   58.270  1.00 44.59  ? 93  VAL F N   1 
ATOM   12152 C  CA  . VAL F 1 93  ? 57.927  1.833   56.945  1.00 36.10  ? 93  VAL F CA  1 
ATOM   12153 C  C   . VAL F 1 93  ? 57.439  2.763   55.827  1.00 36.24  ? 93  VAL F C   1 
ATOM   12154 O  O   . VAL F 1 93  ? 58.182  3.087   54.913  1.00 39.85  ? 93  VAL F O   1 
ATOM   12155 C  CB  . VAL F 1 93  ? 57.451  0.413   56.652  1.00 37.02  ? 93  VAL F CB  1 
ATOM   12156 C  CG1 . VAL F 1 93  ? 57.738  -0.061  55.228  1.00 32.33  ? 93  VAL F CG1 1 
ATOM   12157 C  CG2 . VAL F 1 93  ? 58.013  -0.551  57.680  1.00 42.21  ? 93  VAL F CG2 1 
ATOM   12158 N  N   . HIS F 1 94  ? 56.156  3.138   55.863  1.00 32.02  ? 94  HIS F N   1 
ATOM   12159 C  CA  . HIS F 1 94  ? 55.525  3.874   54.783  1.00 27.31  ? 94  HIS F CA  1 
ATOM   12160 C  C   . HIS F 1 94  ? 55.098  5.260   55.278  1.00 28.85  ? 94  HIS F C   1 
ATOM   12161 O  O   . HIS F 1 94  ? 54.729  5.442   56.412  1.00 36.18  ? 94  HIS F O   1 
ATOM   12162 C  CB  . HIS F 1 94  ? 54.302  3.105   54.307  1.00 24.41  ? 94  HIS F CB  1 
ATOM   12163 C  CG  . HIS F 1 94  ? 54.583  1.744   53.759  1.00 27.19  ? 94  HIS F CG  1 
ATOM   12164 N  ND1 . HIS F 1 94  ? 55.235  1.517   52.547  1.00 23.77  ? 94  HIS F ND1 1 
ATOM   12165 C  CD2 . HIS F 1 94  ? 54.219  0.503   54.267  1.00 30.31  ? 94  HIS F CD2 1 
ATOM   12166 C  CE1 . HIS F 1 94  ? 55.281  0.200   52.317  1.00 21.67  ? 94  HIS F CE1 1 
ATOM   12167 N  NE2 . HIS F 1 94  ? 54.692  -0.446  53.364  1.00 28.94  ? 94  HIS F NE2 1 
ATOM   12168 N  N   . ARG F 1 95  ? 55.061  6.227   54.380  1.00 31.98  ? 95  ARG F N   1 
ATOM   12169 C  CA  . ARG F 1 95  ? 54.831  7.629   54.668  1.00 34.64  ? 95  ARG F CA  1 
ATOM   12170 C  C   . ARG F 1 95  ? 53.686  8.094   53.759  1.00 32.72  ? 95  ARG F C   1 
ATOM   12171 O  O   . ARG F 1 95  ? 53.659  7.789   52.571  1.00 37.37  ? 95  ARG F O   1 
ATOM   12172 C  CB  . ARG F 1 95  ? 56.211  8.234   54.311  1.00 45.55  ? 95  ARG F CB  1 
ATOM   12173 C  CG  . ARG F 1 95  ? 56.454  9.743   54.278  1.00 55.91  ? 95  ARG F CG  1 
ATOM   12174 C  CD  . ARG F 1 95  ? 57.872  10.254  54.641  1.00 50.46  ? 95  ARG F CD  1 
ATOM   12175 N  NE  . ARG F 1 95  ? 58.368  11.146  53.593  1.00 50.34  ? 95  ARG F NE  1 
ATOM   12176 N  N   . ALA F 1 96  ? 52.722  8.825   54.304  1.00 32.83  ? 96  ALA F N   1 
ATOM   12177 C  CA  . ALA F 1 96  ? 51.753  9.566   53.520  1.00 31.01  ? 96  ALA F CA  1 
ATOM   12178 C  C   . ALA F 1 96  ? 52.179  11.029  53.446  1.00 30.58  ? 96  ALA F C   1 
ATOM   12179 O  O   . ALA F 1 96  ? 52.005  11.773  54.439  1.00 34.71  ? 96  ALA F O   1 
ATOM   12180 C  CB  . ALA F 1 96  ? 50.384  9.428   54.195  1.00 36.50  ? 96  ALA F CB  1 
ATOM   12181 N  N   . VAL F 1 97  ? 52.671  11.444  52.271  1.00 29.30  ? 97  VAL F N   1 
ATOM   12182 C  CA  . VAL F 1 97  ? 53.104  12.840  52.098  1.00 35.34  ? 97  VAL F CA  1 
ATOM   12183 C  C   . VAL F 1 97  ? 51.936  13.811  51.932  1.00 34.45  ? 97  VAL F C   1 
ATOM   12184 O  O   . VAL F 1 97  ? 50.834  13.434  51.521  1.00 30.82  ? 97  VAL F O   1 
ATOM   12185 C  CB  . VAL F 1 97  ? 54.012  13.003  50.881  1.00 37.22  ? 97  VAL F CB  1 
ATOM   12186 C  CG1 . VAL F 1 97  ? 55.270  12.221  51.088  1.00 47.87  ? 97  VAL F CG1 1 
ATOM   12187 C  CG2 . VAL F 1 97  ? 53.327  12.522  49.604  1.00 40.26  ? 97  VAL F CG2 1 
ATOM   12188 N  N   . ALA F 1 98  ? 52.212  15.074  52.247  1.00 29.90  ? 98  ALA F N   1 
ATOM   12189 C  CA  . ALA F 1 98  ? 51.291  16.170  52.002  1.00 28.89  ? 98  ALA F CA  1 
ATOM   12190 C  C   . ALA F 1 98  ? 51.876  17.004  50.895  1.00 28.90  ? 98  ALA F C   1 
ATOM   12191 O  O   . ALA F 1 98  ? 52.987  17.462  51.041  1.00 33.32  ? 98  ALA F O   1 
ATOM   12192 C  CB  . ALA F 1 98  ? 51.088  17.076  53.188  1.00 26.45  ? 98  ALA F CB  1 
ATOM   12193 N  N   . THR F 1 99  ? 51.087  17.266  49.866  1.00 25.44  ? 99  THR F N   1 
ATOM   12194 C  CA  . THR F 1 99  ? 51.570  18.058  48.771  1.00 24.13  ? 99  THR F CA  1 
ATOM   12195 C  C   . THR F 1 99  ? 50.655  19.227  48.597  1.00 23.48  ? 99  THR F C   1 
ATOM   12196 O  O   . THR F 1 99  ? 49.521  19.206  49.022  1.00 26.20  ? 99  THR F O   1 
ATOM   12197 C  CB  . THR F 1 99  ? 51.693  17.211  47.503  1.00 27.60  ? 99  THR F CB  1 
ATOM   12198 O  OG1 . THR F 1 99  ? 50.465  16.548  47.250  1.00 23.09  ? 99  THR F OG1 1 
ATOM   12199 C  CG2 . THR F 1 99  ? 52.694  16.086  47.673  1.00 30.45  ? 99  THR F CG2 1 
ATOM   12200 N  N   . PRO F 1 100 ? 51.155  20.290  47.971  1.00 28.24  ? 100 PRO F N   1 
ATOM   12201 C  CA  . PRO F 1 100 ? 50.366  21.501  47.710  1.00 28.25  ? 100 PRO F CA  1 
ATOM   12202 C  C   . PRO F 1 100 ? 49.193  21.294  46.775  1.00 25.10  ? 100 PRO F C   1 
ATOM   12203 O  O   . PRO F 1 100 ? 49.253  20.492  45.846  1.00 27.25  ? 100 PRO F O   1 
ATOM   12204 C  CB  . PRO F 1 100 ? 51.364  22.435  46.999  1.00 29.44  ? 100 PRO F CB  1 
ATOM   12205 C  CG  . PRO F 1 100 ? 52.709  21.707  46.992  1.00 31.25  ? 100 PRO F CG  1 
ATOM   12206 C  CD  . PRO F 1 100 ? 52.528  20.315  47.443  1.00 27.05  ? 100 PRO F CD  1 
ATOM   12207 N  N   . GLY F 1 101 ? 48.151  22.059  47.065  1.00 28.55  ? 101 GLY F N   1 
ATOM   12208 C  CA  . GLY F 1 101 ? 46.868  22.031  46.377  1.00 27.22  ? 101 GLY F CA  1 
ATOM   12209 C  C   . GLY F 1 101 ? 45.874  23.009  47.026  1.00 23.54  ? 101 GLY F C   1 
ATOM   12210 O  O   . GLY F 1 101 ? 45.450  22.851  48.149  1.00 21.01  ? 101 GLY F O   1 
ATOM   12211 N  N   . ASP F 1 102 ? 45.448  24.000  46.290  1.00 22.05  ? 102 ASP F N   1 
ATOM   12212 C  CA  . ASP F 1 102 ? 44.506  24.980  46.781  1.00 24.77  ? 102 ASP F CA  1 
ATOM   12213 C  C   . ASP F 1 102 ? 43.118  24.683  46.257  1.00 23.43  ? 102 ASP F C   1 
ATOM   12214 O  O   . ASP F 1 102 ? 42.149  24.933  46.928  1.00 25.10  ? 102 ASP F O   1 
ATOM   12215 C  CB  . ASP F 1 102 ? 44.934  26.396  46.388  1.00 27.34  ? 102 ASP F CB  1 
ATOM   12216 C  CG  . ASP F 1 102 ? 46.159  26.918  47.154  1.00 25.98  ? 102 ASP F CG  1 
ATOM   12217 O  OD1 . ASP F 1 102 ? 46.418  26.428  48.273  1.00 25.81  ? 102 ASP F OD1 1 
ATOM   12218 O  OD2 . ASP F 1 102 ? 46.866  27.734  46.582  1.00 24.81  ? 102 ASP F OD2 1 
ATOM   12219 N  N   . LEU F 1 103 ? 43.031  24.213  45.021  1.00 25.98  ? 103 LEU F N   1 
ATOM   12220 C  CA  . LEU F 1 103 ? 41.764  23.958  44.371  1.00 24.70  ? 103 LEU F CA  1 
ATOM   12221 C  C   . LEU F 1 103 ? 41.833  22.585  43.783  1.00 20.21  ? 103 LEU F C   1 
ATOM   12222 O  O   . LEU F 1 103 ? 42.837  22.264  43.171  1.00 22.89  ? 103 LEU F O   1 
ATOM   12223 C  CB  . LEU F 1 103 ? 41.484  24.950  43.255  1.00 24.30  ? 103 LEU F CB  1 
ATOM   12224 C  CG  . LEU F 1 103 ? 41.230  26.385  43.683  1.00 24.85  ? 103 LEU F CG  1 
ATOM   12225 C  CD1 . LEU F 1 103 ? 41.045  27.272  42.443  1.00 29.84  ? 103 LEU F CD1 1 
ATOM   12226 C  CD2 . LEU F 1 103 ? 40.008  26.454  44.546  1.00 29.65  ? 103 LEU F CD2 1 
ATOM   12227 N  N   . LEU F 1 104 ? 40.739  21.856  43.958  1.00 21.58  ? 104 LEU F N   1 
ATOM   12228 C  CA  . LEU F 1 104 ? 40.526  20.576  43.304  1.00 23.00  ? 104 LEU F CA  1 
ATOM   12229 C  C   . LEU F 1 104 ? 39.348  20.702  42.345  1.00 23.79  ? 104 LEU F C   1 
ATOM   12230 O  O   . LEU F 1 104 ? 38.300  21.222  42.720  1.00 22.43  ? 104 LEU F O   1 
ATOM   12231 C  CB  . LEU F 1 104 ? 40.230  19.517  44.358  1.00 24.98  ? 104 LEU F CB  1 
ATOM   12232 C  CG  . LEU F 1 104 ? 39.702  18.190  43.845  1.00 27.12  ? 104 LEU F CG  1 
ATOM   12233 C  CD1 . LEU F 1 104 ? 40.838  17.426  43.213  1.00 24.37  ? 104 LEU F CD1 1 
ATOM   12234 C  CD2 . LEU F 1 104 ? 39.048  17.428  44.974  1.00 31.85  ? 104 LEU F CD2 1 
ATOM   12235 N  N   . PHE F 1 105 ? 39.533  20.190  41.113  1.00 23.19  ? 105 PHE F N   1 
ATOM   12236 C  CA  . PHE F 1 105 ? 38.423  19.981  40.198  1.00 21.13  ? 105 PHE F CA  1 
ATOM   12237 C  C   . PHE F 1 105 ? 38.348  18.494  39.944  1.00 17.35  ? 105 PHE F C   1 
ATOM   12238 O  O   . PHE F 1 105 ? 39.279  17.922  39.431  1.00 20.66  ? 105 PHE F O   1 
ATOM   12239 C  CB  . PHE F 1 105 ? 38.581  20.835  38.951  1.00 22.35  ? 105 PHE F CB  1 
ATOM   12240 C  CG  . PHE F 1 105 ? 38.619  22.312  39.272  1.00 23.50  ? 105 PHE F CG  1 
ATOM   12241 C  CD1 . PHE F 1 105 ? 37.476  23.038  39.556  1.00 26.46  ? 105 PHE F CD1 1 
ATOM   12242 C  CD2 . PHE F 1 105 ? 39.812  22.971  39.244  1.00 26.08  ? 105 PHE F CD2 1 
ATOM   12243 C  CE1 . PHE F 1 105 ? 37.554  24.404  39.804  1.00 25.87  ? 105 PHE F CE1 1 
ATOM   12244 C  CE2 . PHE F 1 105 ? 39.859  24.344  39.476  1.00 24.86  ? 105 PHE F CE2 1 
ATOM   12245 C  CZ  . PHE F 1 105 ? 38.750  25.041  39.780  1.00 23.14  ? 105 PHE F CZ  1 
ATOM   12246 N  N   . HIS F 1 106 ? 37.250  17.892  40.387  1.00 19.13  ? 106 HIS F N   1 
ATOM   12247 C  CA  . HIS F 1 106 ? 36.995  16.464  40.228  1.00 18.50  ? 106 HIS F CA  1 
ATOM   12248 C  C   . HIS F 1 106 ? 35.893  16.351  39.192  1.00 20.33  ? 106 HIS F C   1 
ATOM   12249 O  O   . HIS F 1 106 ? 34.723  16.620  39.503  1.00 19.87  ? 106 HIS F O   1 
ATOM   12250 C  CB  . HIS F 1 106 ? 36.578  15.820  41.550  1.00 19.02  ? 106 HIS F CB  1 
ATOM   12251 C  CG  . HIS F 1 106 ? 36.281  14.373  41.456  1.00 20.60  ? 106 HIS F CG  1 
ATOM   12252 N  ND1 . HIS F 1 106 ? 35.503  13.703  42.369  1.00 19.94  ? 106 HIS F ND1 1 
ATOM   12253 C  CD2 . HIS F 1 106 ? 36.684  13.461  40.561  1.00 21.00  ? 106 HIS F CD2 1 
ATOM   12254 C  CE1 . HIS F 1 106 ? 35.487  12.424  42.036  1.00 20.23  ? 106 HIS F CE1 1 
ATOM   12255 N  NE2 . HIS F 1 106 ? 36.162  12.266  40.904  1.00 18.45  ? 106 HIS F NE2 1 
ATOM   12256 N  N   . ILE F 1 107 ? 36.345  16.094  37.956  1.00 20.09  ? 107 ILE F N   1 
ATOM   12257 C  CA  . ILE F 1 107 ? 35.445  16.155  36.812  1.00 22.13  ? 107 ILE F CA  1 
ATOM   12258 C  C   . ILE F 1 107 ? 35.185  14.730  36.333  1.00 20.31  ? 107 ILE F C   1 
ATOM   12259 O  O   . ILE F 1 107 ? 36.143  13.962  36.163  1.00 20.29  ? 107 ILE F O   1 
ATOM   12260 C  CB  . ILE F 1 107 ? 36.049  17.018  35.708  1.00 23.71  ? 107 ILE F CB  1 
ATOM   12261 C  CG1 . ILE F 1 107 ? 36.375  18.453  36.211  1.00 22.68  ? 107 ILE F CG1 1 
ATOM   12262 C  CG2 . ILE F 1 107 ? 35.125  16.996  34.477  1.00 25.01  ? 107 ILE F CG2 1 
ATOM   12263 C  CD1 . ILE F 1 107 ? 37.220  19.235  35.220  1.00 21.66  ? 107 ILE F CD1 1 
ATOM   12264 N  N   . ARG F 1 108 ? 33.897  14.371  36.237  1.00 17.91  ? 108 ARG F N   1 
ATOM   12265 C  CA  . ARG F 1 108 ? 33.559  13.019  35.850  1.00 21.65  ? 108 ARG F CA  1 
ATOM   12266 C  C   . ARG F 1 108 ? 32.545  13.027  34.710  1.00 21.94  ? 108 ARG F C   1 
ATOM   12267 O  O   . ARG F 1 108 ? 31.777  13.965  34.568  1.00 25.19  ? 108 ARG F O   1 
ATOM   12268 C  CB  . ARG F 1 108 ? 33.004  12.250  37.045  1.00 22.75  ? 108 ARG F CB  1 
ATOM   12269 C  CG  . ARG F 1 108 ? 34.026  11.881  38.096  1.00 21.11  ? 108 ARG F CG  1 
ATOM   12270 C  CD  . ARG F 1 108 ? 33.321  11.336  39.312  1.00 23.62  ? 108 ARG F CD  1 
ATOM   12271 N  NE  . ARG F 1 108 ? 32.549  12.293  40.132  1.00 24.06  ? 108 ARG F NE  1 
ATOM   12272 C  CZ  . ARG F 1 108 ? 32.070  11.999  41.326  1.00 25.09  ? 108 ARG F CZ  1 
ATOM   12273 N  NH1 . ARG F 1 108 ? 32.250  10.793  41.799  1.00 26.31  ? 108 ARG F NH1 1 
ATOM   12274 N  NH2 . ARG F 1 108 ? 31.514  12.866  42.106  1.00 25.10  ? 108 ARG F NH2 1 
ATOM   12275 N  N   . ALA F 1 109 ? 32.576  11.982  33.894  1.00 21.12  ? 109 ALA F N   1 
ATOM   12276 C  CA  . ALA F 1 109 ? 31.551  11.836  32.881  1.00 24.00  ? 109 ALA F CA  1 
ATOM   12277 C  C   . ALA F 1 109 ? 31.581  10.419  32.333  1.00 25.95  ? 109 ALA F C   1 
ATOM   12278 O  O   . ALA F 1 109 ? 32.513  9.649   32.625  1.00 24.78  ? 109 ALA F O   1 
ATOM   12279 C  CB  . ALA F 1 109 ? 31.836  12.811  31.762  1.00 27.25  ? 109 ALA F CB  1 
ATOM   12280 N  N   . SER F 1 110 ? 30.673  10.133  31.410  1.00 25.52  ? 110 SER F N   1 
ATOM   12281 C  CA  . SER F 1 110 ? 30.749  8.859   30.703  1.00 28.03  ? 110 SER F CA  1 
ATOM   12282 C  C   . SER F 1 110 ? 31.819  8.849   29.623  1.00 28.76  ? 110 SER F C   1 
ATOM   12283 O  O   . SER F 1 110 ? 32.082  7.825   29.103  1.00 29.97  ? 110 SER F O   1 
ATOM   12284 C  CB  . SER F 1 110 ? 29.399  8.440   30.158  1.00 27.49  ? 110 SER F CB  1 
ATOM   12285 O  OG  . SER F 1 110 ? 29.011  9.352   29.165  1.00 31.09  ? 110 SER F OG  1 
ATOM   12286 N  N   . ARG F 1 111 ? 32.434  9.958   29.256  1.00 31.17  ? 111 ARG F N   1 
ATOM   12287 C  CA  . ARG F 1 111 ? 33.420  9.971   28.179  1.00 32.40  ? 111 ARG F CA  1 
ATOM   12288 C  C   . ARG F 1 111 ? 34.448  11.046  28.534  1.00 26.22  ? 111 ARG F C   1 
ATOM   12289 O  O   . ARG F 1 111 ? 34.093  12.125  28.982  1.00 25.53  ? 111 ARG F O   1 
ATOM   12290 C  CB  . ARG F 1 111 ? 32.831  10.116  26.745  1.00 39.50  ? 111 ARG F CB  1 
ATOM   12291 C  CG  . ARG F 1 111 ? 31.406  10.667  26.529  1.00 45.38  ? 111 ARG F CG  1 
ATOM   12292 C  CD  . ARG F 1 111 ? 30.759  10.930  25.114  1.00 48.94  ? 111 ARG F CD  1 
ATOM   12293 N  NE  . ARG F 1 111 ? 31.677  11.180  23.984  1.00 79.83  ? 111 ARG F NE  1 
ATOM   12294 C  CZ  . ARG F 1 111 ? 32.181  10.370  22.966  1.00 68.57  ? 111 ARG F CZ  1 
ATOM   12295 N  NH1 . ARG F 1 111 ? 31.991  9.079   22.918  1.00 71.52  ? 111 ARG F NH1 1 
ATOM   12296 N  NH2 . ARG F 1 111 ? 32.944  10.824  21.979  1.00 68.24  ? 111 ARG F NH2 1 
ATOM   12297 N  N   . LEU F 1 112 ? 35.689  10.780  28.208  1.00 23.07  ? 112 LEU F N   1 
ATOM   12298 C  CA  . LEU F 1 112 ? 36.773  11.696  28.516  1.00 26.59  ? 112 LEU F CA  1 
ATOM   12299 C  C   . LEU F 1 112 ? 36.672  13.071  27.833  1.00 27.77  ? 112 LEU F C   1 
ATOM   12300 O  O   . LEU F 1 112 ? 37.064  14.075  28.425  1.00 28.96  ? 112 LEU F O   1 
ATOM   12301 C  CB  . LEU F 1 112 ? 38.079  11.042  28.137  1.00 26.18  ? 112 LEU F CB  1 
ATOM   12302 C  CG  . LEU F 1 112 ? 39.287  11.778  28.695  1.00 31.36  ? 112 LEU F CG  1 
ATOM   12303 C  CD1 . LEU F 1 112 ? 39.152  11.855  30.196  1.00 37.53  ? 112 LEU F CD1 1 
ATOM   12304 C  CD2 . LEU F 1 112 ? 40.588  11.103  28.336  1.00 36.32  ? 112 LEU F CD2 1 
ATOM   12305 N  N   . ASP F 1 113 ? 36.121  13.124  26.616  1.00 28.08  ? 113 ASP F N   1 
ATOM   12306 C  CA  . ASP F 1 113 ? 36.053  14.362  25.869  1.00 29.59  ? 113 ASP F CA  1 
ATOM   12307 C  C   . ASP F 1 113 ? 35.246  15.420  26.617  1.00 26.02  ? 113 ASP F C   1 
ATOM   12308 O  O   . ASP F 1 113 ? 35.558  16.603  26.514  1.00 25.52  ? 113 ASP F O   1 
ATOM   12309 C  CB  . ASP F 1 113 ? 35.480  14.223  24.453  1.00 36.29  ? 113 ASP F CB  1 
ATOM   12310 C  CG  . ASP F 1 113 ? 34.060  13.676  24.336  1.00 32.76  ? 113 ASP F CG  1 
ATOM   12311 O  OD1 . ASP F 1 113 ? 33.941  12.584  24.874  1.00 37.24  ? 113 ASP F OD1 1 
ATOM   12312 O  OD2 . ASP F 1 113 ? 33.121  14.346  23.773  1.00 25.51  ? 113 ASP F OD2 1 
ATOM   12313 N  N   . LEU F 1 114 ? 34.181  15.028  27.308  1.00 24.13  ? 114 LEU F N   1 
ATOM   12314 C  CA  . LEU F 1 114 ? 33.393  16.010  28.028  1.00 24.49  ? 114 LEU F CA  1 
ATOM   12315 C  C   . LEU F 1 114 ? 34.173  16.545  29.207  1.00 22.63  ? 114 LEU F C   1 
ATOM   12316 O  O   . LEU F 1 114 ? 34.059  17.731  29.472  1.00 24.18  ? 114 LEU F O   1 
ATOM   12317 C  CB  . LEU F 1 114 ? 32.119  15.365  28.550  1.00 27.89  ? 114 LEU F CB  1 
ATOM   12318 C  CG  . LEU F 1 114 ? 31.091  14.992  27.480  1.00 30.80  ? 114 LEU F CG  1 
ATOM   12319 C  CD1 . LEU F 1 114 ? 30.030  14.079  28.061  1.00 30.57  ? 114 LEU F CD1 1 
ATOM   12320 C  CD2 . LEU F 1 114 ? 30.454  16.252  26.961  1.00 26.66  ? 114 LEU F CD2 1 
ATOM   12321 N  N   . CYS F 1 115 ? 34.871  15.625  29.915  1.00 21.90  ? 115 CYS F N   1 
ATOM   12322 C  CA  . CYS F 1 115 ? 35.750  16.008  30.997  1.00 20.60  ? 115 CYS F CA  1 
ATOM   12323 C  C   . CYS F 1 115 ? 36.778  17.038  30.493  1.00 21.07  ? 115 CYS F C   1 
ATOM   12324 O  O   . CYS F 1 115 ? 37.013  18.065  31.139  1.00 22.18  ? 115 CYS F O   1 
ATOM   12325 C  CB  . CYS F 1 115 ? 36.487  14.806  31.572  1.00 21.59  ? 115 CYS F CB  1 
ATOM   12326 S  SG  . CYS F 1 115 ? 35.422  13.560  32.345  1.00 23.30  ? 115 CYS F SG  1 
ATOM   12327 N  N   . PHE F 1 116 ? 37.423  16.732  29.358  1.00 19.32  ? 116 PHE F N   1 
ATOM   12328 C  CA  . PHE F 1 116 ? 38.460  17.598  28.812  1.00 19.56  ? 116 PHE F CA  1 
ATOM   12329 C  C   . PHE F 1 116 ? 37.912  18.961  28.419  1.00 18.59  ? 116 PHE F C   1 
ATOM   12330 O  O   . PHE F 1 116 ? 38.525  20.017  28.604  1.00 18.79  ? 116 PHE F O   1 
ATOM   12331 C  CB  . PHE F 1 116 ? 39.080  16.892  27.614  1.00 24.73  ? 116 PHE F CB  1 
ATOM   12332 C  CG  . PHE F 1 116 ? 40.410  17.517  27.210  1.00 28.26  ? 116 PHE F CG  1 
ATOM   12333 C  CD1 . PHE F 1 116 ? 41.584  17.113  27.799  1.00 30.72  ? 116 PHE F CD1 1 
ATOM   12334 C  CD2 . PHE F 1 116 ? 40.480  18.508  26.264  1.00 27.79  ? 116 PHE F CD2 1 
ATOM   12335 C  CE1 . PHE F 1 116 ? 42.777  17.676  27.433  1.00 30.84  ? 116 PHE F CE1 1 
ATOM   12336 C  CE2 . PHE F 1 116 ? 41.680  19.069  25.917  1.00 25.03  ? 116 PHE F CE2 1 
ATOM   12337 C  CZ  . PHE F 1 116 ? 42.815  18.642  26.483  1.00 27.16  ? 116 PHE F CZ  1 
ATOM   12338 N  N   . ALA F 1 117 ? 36.719  18.957  27.863  1.00 17.68  ? 117 ALA F N   1 
ATOM   12339 C  CA  . ALA F 1 117 ? 36.137  20.194  27.404  1.00 18.64  ? 117 ALA F CA  1 
ATOM   12340 C  C   . ALA F 1 117 ? 35.827  21.107  28.578  1.00 19.16  ? 117 ALA F C   1 
ATOM   12341 O  O   . ALA F 1 117 ? 36.035  22.300  28.482  1.00 21.28  ? 117 ALA F O   1 
ATOM   12342 C  CB  . ALA F 1 117 ? 34.922  19.872  26.614  1.00 18.91  ? 117 ALA F CB  1 
ATOM   12343 N  N   . LEU F 1 118 ? 35.309  20.560  29.683  1.00 18.15  ? 118 LEU F N   1 
ATOM   12344 C  CA  . LEU F 1 118 ? 35.039  21.351  30.853  1.00 19.04  ? 118 LEU F CA  1 
ATOM   12345 C  C   . LEU F 1 118 ? 36.359  21.834  31.499  1.00 21.56  ? 118 LEU F C   1 
ATOM   12346 O  O   . LEU F 1 118 ? 36.474  23.002  31.928  1.00 19.33  ? 118 LEU F O   1 
ATOM   12347 C  CB  . LEU F 1 118 ? 34.143  20.568  31.829  1.00 18.60  ? 118 LEU F CB  1 
ATOM   12348 C  CG  . LEU F 1 118 ? 33.838  21.338  33.135  1.00 20.48  ? 118 LEU F CG  1 
ATOM   12349 C  CD1 . LEU F 1 118 ? 33.199  22.687  32.877  1.00 19.47  ? 118 LEU F CD1 1 
ATOM   12350 C  CD2 . LEU F 1 118 ? 32.924  20.598  34.052  1.00 20.44  ? 118 LEU F CD2 1 
ATOM   12351 N  N   . ALA F 1 119 ? 37.363  20.937  31.596  1.00 21.39  ? 119 ALA F N   1 
ATOM   12352 C  CA  . ALA F 1 119 ? 38.667  21.289  32.147  1.00 20.43  ? 119 ALA F CA  1 
ATOM   12353 C  C   . ALA F 1 119 ? 39.304  22.427  31.346  1.00 21.36  ? 119 ALA F C   1 
ATOM   12354 O  O   . ALA F 1 119 ? 39.945  23.295  31.893  1.00 23.36  ? 119 ALA F O   1 
ATOM   12355 C  CB  . ALA F 1 119 ? 39.553  20.065  32.170  1.00 20.05  ? 119 ALA F CB  1 
ATOM   12356 N  N   . THR F 1 120 ? 39.141  22.390  30.038  1.00 20.61  ? 120 THR F N   1 
ATOM   12357 C  CA  . THR F 1 120 ? 39.673  23.418  29.178  1.00 22.08  ? 120 THR F CA  1 
ATOM   12358 C  C   . THR F 1 120 ? 39.007  24.744  29.517  1.00 21.36  ? 120 THR F C   1 
ATOM   12359 O  O   . THR F 1 120 ? 39.662  25.771  29.566  1.00 25.25  ? 120 THR F O   1 
ATOM   12360 C  CB  . THR F 1 120 ? 39.429  23.023  27.707  1.00 24.01  ? 120 THR F CB  1 
ATOM   12361 O  OG1 . THR F 1 120 ? 40.306  21.925  27.458  1.00 25.30  ? 120 THR F OG1 1 
ATOM   12362 C  CG2 . THR F 1 120 ? 39.789  24.117  26.724  1.00 22.44  ? 120 THR F CG2 1 
ATOM   12363 N  N   . GLU F 1 121 ? 37.691  24.768  29.646  1.00 20.67  ? 121 GLU F N   1 
ATOM   12364 C  CA  . GLU F 1 121 ? 37.006  26.008  29.897  1.00 23.01  ? 121 GLU F CA  1 
ATOM   12365 C  C   . GLU F 1 121 ? 37.416  26.612  31.252  1.00 24.77  ? 121 GLU F C   1 
ATOM   12366 O  O   . GLU F 1 121 ? 37.622  27.819  31.357  1.00 23.94  ? 121 GLU F O   1 
ATOM   12367 C  CB  . GLU F 1 121 ? 35.492  25.822  29.858  1.00 27.13  ? 121 GLU F CB  1 
ATOM   12368 C  CG  . GLU F 1 121 ? 34.882  25.791  28.464  1.00 35.70  ? 121 GLU F CG  1 
ATOM   12369 C  CD  . GLU F 1 121 ? 34.857  27.164  27.798  1.00 36.54  ? 121 GLU F CD  1 
ATOM   12370 O  OE1 . GLU F 1 121 ? 34.872  28.254  28.440  1.00 33.68  ? 121 GLU F OE1 1 
ATOM   12371 O  OE2 . GLU F 1 121 ? 34.900  27.054  26.575  1.00 47.14  ? 121 GLU F OE2 1 
ATOM   12372 N  N   . ILE F 1 122 ? 37.477  25.773  32.298  1.00 26.69  ? 122 ILE F N   1 
ATOM   12373 C  CA  . ILE F 1 122 ? 37.849  26.204  33.647  1.00 25.62  ? 122 ILE F CA  1 
ATOM   12374 C  C   . ILE F 1 122 ? 39.252  26.796  33.623  1.00 24.27  ? 122 ILE F C   1 
ATOM   12375 O  O   . ILE F 1 122 ? 39.443  27.930  34.054  1.00 22.39  ? 122 ILE F O   1 
ATOM   12376 C  CB  . ILE F 1 122 ? 37.704  25.024  34.638  1.00 25.35  ? 122 ILE F CB  1 
ATOM   12377 C  CG1 . ILE F 1 122 ? 36.224  24.775  34.917  1.00 28.90  ? 122 ILE F CG1 1 
ATOM   12378 C  CG2 . ILE F 1 122 ? 38.509  25.177  35.924  1.00 27.68  ? 122 ILE F CG2 1 
ATOM   12379 C  CD1 . ILE F 1 122 ? 36.012  23.447  35.626  1.00 35.29  ? 122 ILE F CD1 1 
ATOM   12380 N  N   . MET F 1 123 ? 40.207  26.059  33.046  1.00 24.66  ? 123 MET F N   1 
ATOM   12381 C  CA  . MET F 1 123 ? 41.574  26.517  33.077  1.00 29.35  ? 123 MET F CA  1 
ATOM   12382 C  C   . MET F 1 123 ? 41.743  27.747  32.195  1.00 30.60  ? 123 MET F C   1 
ATOM   12383 O  O   . MET F 1 123 ? 42.608  28.571  32.483  1.00 32.16  ? 123 MET F O   1 
ATOM   12384 C  CB  . MET F 1 123 ? 42.558  25.429  32.656  1.00 29.97  ? 123 MET F CB  1 
ATOM   12385 C  CG  . MET F 1 123 ? 42.671  24.380  33.686  1.00 34.74  ? 123 MET F CG  1 
ATOM   12386 S  SD  . MET F 1 123 ? 43.557  24.940  35.148  1.00 42.71  ? 123 MET F SD  1 
ATOM   12387 C  CE  . MET F 1 123 ? 44.982  25.742  34.410  1.00 44.90  ? 123 MET F CE  1 
ATOM   12388 N  N   . GLY F 1 124 ? 40.925  27.850  31.149  1.00 27.20  ? 124 GLY F N   1 
ATOM   12389 C  CA  . GLY F 1 124 ? 40.899  29.042  30.322  1.00 30.38  ? 124 GLY F CA  1 
ATOM   12390 C  C   . GLY F 1 124 ? 40.657  30.308  31.126  1.00 27.93  ? 124 GLY F C   1 
ATOM   12391 O  O   . GLY F 1 124 ? 41.334  31.294  30.932  1.00 31.45  ? 124 GLY F O   1 
ATOM   12392 N  N   . ARG F 1 125 ? 39.686  30.271  32.023  1.00 32.23  ? 125 ARG F N   1 
ATOM   12393 C  CA  . ARG F 1 125 ? 39.365  31.412  32.872  1.00 31.40  ? 125 ARG F CA  1 
ATOM   12394 C  C   . ARG F 1 125 ? 40.444  31.611  33.959  1.00 32.50  ? 125 ARG F C   1 
ATOM   12395 O  O   . ARG F 1 125 ? 40.571  32.710  34.491  1.00 28.64  ? 125 ARG F O   1 
ATOM   12396 C  CB  . ARG F 1 125 ? 38.020  31.136  33.532  1.00 29.41  ? 125 ARG F CB  1 
ATOM   12397 C  CG  . ARG F 1 125 ? 36.851  30.874  32.600  1.00 32.52  ? 125 ARG F CG  1 
ATOM   12398 C  CD  . ARG F 1 125 ? 36.234  32.160  32.218  1.00 42.23  ? 125 ARG F CD  1 
ATOM   12399 N  NE  . ARG F 1 125 ? 35.868  33.046  33.339  1.00 47.81  ? 125 ARG F NE  1 
ATOM   12400 C  CZ  . ARG F 1 125 ? 34.694  33.015  33.971  1.00 60.00  ? 125 ARG F CZ  1 
ATOM   12401 N  NH1 . ARG F 1 125 ? 33.647  32.486  33.332  1.00 62.79  ? 125 ARG F NH1 1 
ATOM   12402 N  NH2 . ARG F 1 125 ? 34.561  33.553  35.188  1.00 50.43  ? 125 ARG F NH2 1 
ATOM   12403 N  N   . LEU F 1 126 ? 41.246  30.580  34.294  1.00 25.39  ? 126 LEU F N   1 
ATOM   12404 C  CA  . LEU F 1 126 ? 42.165  30.712  35.400  1.00 24.45  ? 126 LEU F CA  1 
ATOM   12405 C  C   . LEU F 1 126 ? 43.576  31.013  34.934  1.00 31.38  ? 126 LEU F C   1 
ATOM   12406 O  O   . LEU F 1 126 ? 44.396  31.162  35.856  1.00 30.83  ? 126 LEU F O   1 
ATOM   12407 C  CB  . LEU F 1 126 ? 42.174  29.436  36.238  1.00 20.77  ? 126 LEU F CB  1 
ATOM   12408 C  CG  . LEU F 1 126 ? 40.896  29.166  37.040  1.00 22.38  ? 126 LEU F CG  1 
ATOM   12409 C  CD1 . LEU F 1 126 ? 40.946  27.824  37.792  1.00 25.19  ? 126 LEU F CD1 1 
ATOM   12410 C  CD2 . LEU F 1 126 ? 40.508  30.303  37.979  1.00 24.62  ? 126 LEU F CD2 1 
ATOM   12411 N  N   . ARG F 1 127 ? 43.860  31.012  33.589  1.00 34.89  ? 127 ARG F N   1 
ATOM   12412 C  CA  . ARG F 1 127 ? 45.227  31.062  33.036  1.00 38.55  ? 127 ARG F CA  1 
ATOM   12413 C  C   . ARG F 1 127 ? 45.777  32.360  33.658  1.00 35.53  ? 127 ARG F C   1 
ATOM   12414 O  O   . ARG F 1 127 ? 45.080  33.371  33.890  1.00 32.63  ? 127 ARG F O   1 
ATOM   12415 C  CB  . ARG F 1 127 ? 45.394  30.733  31.509  1.00 31.87  ? 127 ARG F CB  1 
ATOM   12416 N  N   . GLY F 1 128 ? 47.007  32.326  34.135  1.00 35.80  ? 128 GLY F N   1 
ATOM   12417 C  CA  . GLY F 1 128 ? 47.510  33.557  34.712  1.00 34.15  ? 128 GLY F CA  1 
ATOM   12418 C  C   . GLY F 1 128 ? 47.260  33.671  36.207  1.00 36.81  ? 128 GLY F C   1 
ATOM   12419 O  O   . GLY F 1 128 ? 47.944  34.443  36.817  1.00 41.01  ? 128 GLY F O   1 
ATOM   12420 N  N   . ALA F 1 129 ? 46.325  32.950  36.812  1.00 28.68  ? 129 ALA F N   1 
ATOM   12421 C  CA  . ALA F 1 129 ? 46.040  33.163  38.231  1.00 25.34  ? 129 ALA F CA  1 
ATOM   12422 C  C   . ALA F 1 129 ? 46.356  31.924  39.057  1.00 28.28  ? 129 ALA F C   1 
ATOM   12423 O  O   . ALA F 1 129 ? 46.336  31.973  40.284  1.00 26.63  ? 129 ALA F O   1 
ATOM   12424 C  CB  . ALA F 1 129 ? 44.597  33.528  38.442  1.00 27.98  ? 129 ALA F CB  1 
ATOM   12425 N  N   . VAL F 1 130 ? 46.632  30.791  38.402  1.00 24.78  ? 130 VAL F N   1 
ATOM   12426 C  CA  . VAL F 1 130 ? 46.865  29.577  39.154  1.00 30.36  ? 130 VAL F CA  1 
ATOM   12427 C  C   . VAL F 1 130 ? 48.047  28.881  38.536  1.00 26.19  ? 130 VAL F C   1 
ATOM   12428 O  O   . VAL F 1 130 ? 48.413  29.236  37.446  1.00 31.68  ? 130 VAL F O   1 
ATOM   12429 C  CB  . VAL F 1 130 ? 45.654  28.611  39.177  1.00 33.21  ? 130 VAL F CB  1 
ATOM   12430 C  CG1 . VAL F 1 130 ? 44.405  29.264  39.756  1.00 32.91  ? 130 VAL F CG1 1 
ATOM   12431 C  CG2 . VAL F 1 130 ? 45.350  28.095  37.779  1.00 33.14  ? 130 VAL F CG2 1 
ATOM   12432 N  N   . THR F 1 131 ? 48.595  27.883  39.218  1.00 26.47  ? 131 THR F N   1 
ATOM   12433 C  CA  . THR F 1 131 ? 49.672  27.053  38.695  1.00 28.59  ? 131 THR F CA  1 
ATOM   12434 C  C   . THR F 1 131 ? 49.236  25.605  38.833  1.00 26.45  ? 131 THR F C   1 
ATOM   12435 O  O   . THR F 1 131 ? 48.890  25.181  39.938  1.00 24.81  ? 131 THR F O   1 
ATOM   12436 C  CB  . THR F 1 131 ? 50.987  27.279  39.472  1.00 32.99  ? 131 THR F CB  1 
ATOM   12437 O  OG1 . THR F 1 131 ? 51.333  28.647  39.328  1.00 35.53  ? 131 THR F OG1 1 
ATOM   12438 C  CG2 . THR F 1 131 ? 52.125  26.373  39.027  1.00 28.88  ? 131 THR F CG2 1 
ATOM   12439 N  N   . PRO F 1 132 ? 49.279  24.808  37.747  1.00 28.79  ? 132 PRO F N   1 
ATOM   12440 C  CA  . PRO F 1 132 ? 48.901  23.403  37.807  1.00 30.63  ? 132 PRO F CA  1 
ATOM   12441 C  C   . PRO F 1 132 ? 49.811  22.674  38.754  1.00 30.27  ? 132 PRO F C   1 
ATOM   12442 O  O   . PRO F 1 132 ? 50.985  22.844  38.607  1.00 34.60  ? 132 PRO F O   1 
ATOM   12443 C  CB  . PRO F 1 132 ? 49.193  22.942  36.384  1.00 30.20  ? 132 PRO F CB  1 
ATOM   12444 C  CG  . PRO F 1 132 ? 48.951  24.157  35.581  1.00 33.60  ? 132 PRO F CG  1 
ATOM   12445 C  CD  . PRO F 1 132 ? 49.661  25.208  36.398  1.00 28.85  ? 132 PRO F CD  1 
ATOM   12446 N  N   . GLN F 1 133 ? 49.310  21.833  39.652  1.00 31.76  ? 133 GLN F N   1 
ATOM   12447 C  CA  . GLN F 1 133 ? 50.159  20.910  40.394  1.00 27.99  ? 133 GLN F CA  1 
ATOM   12448 C  C   . GLN F 1 133 ? 49.976  19.467  39.961  1.00 25.08  ? 133 GLN F C   1 
ATOM   12449 O  O   . GLN F 1 133 ? 50.852  18.668  40.150  1.00 24.68  ? 133 GLN F O   1 
ATOM   12450 C  CB  . GLN F 1 133 ? 49.884  20.851  41.892  1.00 29.92  ? 133 GLN F CB  1 
ATOM   12451 C  CG  . GLN F 1 133 ? 50.104  22.190  42.580  1.00 34.82  ? 133 GLN F CG  1 
ATOM   12452 C  CD  . GLN F 1 133 ? 51.560  22.630  42.506  1.00 38.33  ? 133 GLN F CD  1 
ATOM   12453 O  OE1 . GLN F 1 133 ? 52.464  21.823  42.694  1.00 33.81  ? 133 GLN F OE1 1 
ATOM   12454 N  NE2 . GLN F 1 133 ? 51.804  23.867  42.097  1.00 34.91  ? 133 GLN F NE2 1 
ATOM   12455 N  N   . ASP F 1 134 ? 48.796  19.068  39.537  1.00 22.81  ? 134 ASP F N   1 
ATOM   12456 C  CA  . ASP F 1 134 ? 48.589  17.672  39.169  1.00 24.66  ? 134 ASP F CA  1 
ATOM   12457 C  C   . ASP F 1 134 ? 47.415  17.628  38.205  1.00 21.52  ? 134 ASP F C   1 
ATOM   12458 O  O   . ASP F 1 134 ? 46.499  18.454  38.305  1.00 20.60  ? 134 ASP F O   1 
ATOM   12459 C  CB  . ASP F 1 134 ? 48.339  16.797  40.396  1.00 26.37  ? 134 ASP F CB  1 
ATOM   12460 C  CG  . ASP F 1 134 ? 48.599  15.309  40.250  1.00 29.74  ? 134 ASP F CG  1 
ATOM   12461 O  OD1 . ASP F 1 134 ? 49.279  14.936  39.317  1.00 27.05  ? 134 ASP F OD1 1 
ATOM   12462 O  OD2 . ASP F 1 134 ? 48.088  14.532  41.059  1.00 33.67  ? 134 ASP F OD2 1 
ATOM   12463 N  N   . GLU F 1 135 ? 47.487  16.720  37.227  1.00 20.19  ? 135 GLU F N   1 
ATOM   12464 C  CA  . GLU F 1 135 ? 46.463  16.521  36.225  1.00 21.34  ? 135 GLU F CA  1 
ATOM   12465 C  C   . GLU F 1 135 ? 46.451  15.032  35.933  1.00 22.25  ? 135 GLU F C   1 
ATOM   12466 O  O   . GLU F 1 135 ? 47.447  14.507  35.547  1.00 25.12  ? 135 GLU F O   1 
ATOM   12467 C  CB  . GLU F 1 135 ? 46.779  17.281  34.947  1.00 21.56  ? 135 GLU F CB  1 
ATOM   12468 C  CG  . GLU F 1 135 ? 45.745  17.085  33.860  1.00 25.21  ? 135 GLU F CG  1 
ATOM   12469 C  CD  . GLU F 1 135 ? 45.926  17.942  32.640  1.00 29.46  ? 135 GLU F CD  1 
ATOM   12470 O  OE1 . GLU F 1 135 ? 46.876  18.793  32.612  1.00 28.32  ? 135 GLU F OE1 1 
ATOM   12471 O  OE2 . GLU F 1 135 ? 45.107  17.650  31.709  1.00 29.99  ? 135 GLU F OE2 1 
ATOM   12472 N  N   . VAL F 1 136 ? 45.357  14.334  36.205  1.00 20.97  ? 136 VAL F N   1 
ATOM   12473 C  CA  . VAL F 1 136 ? 45.282  12.902  35.960  1.00 20.89  ? 136 VAL F CA  1 
ATOM   12474 C  C   . VAL F 1 136 ? 44.033  12.622  35.165  1.00 18.35  ? 136 VAL F C   1 
ATOM   12475 O  O   . VAL F 1 136 ? 42.959  13.142  35.493  1.00 22.03  ? 136 VAL F O   1 
ATOM   12476 C  CB  . VAL F 1 136 ? 45.266  12.129  37.283  1.00 24.40  ? 136 VAL F CB  1 
ATOM   12477 C  CG1 . VAL F 1 136 ? 44.921  10.653  37.138  1.00 24.99  ? 136 VAL F CG1 1 
ATOM   12478 C  CG2 . VAL F 1 136 ? 46.581  12.350  38.020  1.00 26.87  ? 136 VAL F CG2 1 
ATOM   12479 N  N   . HIS F 1 137 ? 44.200  11.824  34.111  1.00 18.43  ? 137 HIS F N   1 
ATOM   12480 C  CA  . HIS F 1 137 ? 43.128  11.405  33.243  1.00 20.75  ? 137 HIS F CA  1 
ATOM   12481 C  C   . HIS F 1 137 ? 42.820  9.961   33.594  1.00 23.31  ? 137 HIS F C   1 
ATOM   12482 O  O   . HIS F 1 137 ? 43.633  9.090   33.359  1.00 23.90  ? 137 HIS F O   1 
ATOM   12483 C  CB  . HIS F 1 137 ? 43.601  11.555  31.805  1.00 20.21  ? 137 HIS F CB  1 
ATOM   12484 C  CG  . HIS F 1 137 ? 43.726  12.949  31.324  1.00 23.55  ? 137 HIS F CG  1 
ATOM   12485 N  ND1 . HIS F 1 137 ? 43.920  13.267  29.996  1.00 26.04  ? 137 HIS F ND1 1 
ATOM   12486 C  CD2 . HIS F 1 137 ? 43.775  14.100  31.985  1.00 27.42  ? 137 HIS F CD2 1 
ATOM   12487 C  CE1 . HIS F 1 137 ? 44.066  14.596  29.890  1.00 28.31  ? 137 HIS F CE1 1 
ATOM   12488 N  NE2 . HIS F 1 137 ? 43.978  15.150  31.088  1.00 26.50  ? 137 HIS F NE2 1 
ATOM   12489 N  N   . GLY F 1 138 ? 41.691  9.732   34.231  1.00 24.02  ? 138 GLY F N   1 
ATOM   12490 C  CA  . GLY F 1 138 ? 41.382  8.395   34.708  1.00 24.56  ? 138 GLY F CA  1 
ATOM   12491 C  C   . GLY F 1 138 ? 40.374  7.707   33.799  1.00 22.15  ? 138 GLY F C   1 
ATOM   12492 O  O   . GLY F 1 138 ? 39.519  8.362   33.260  1.00 20.71  ? 138 GLY F O   1 
ATOM   12493 N  N   . PHE F 1 139 ? 40.416  6.381   33.791  1.00 22.84  ? 139 PHE F N   1 
ATOM   12494 C  CA  . PHE F 1 139 ? 39.483  5.531   33.076  1.00 24.02  ? 139 PHE F CA  1 
ATOM   12495 C  C   . PHE F 1 139 ? 39.208  4.268   33.906  1.00 27.54  ? 139 PHE F C   1 
ATOM   12496 O  O   . PHE F 1 139 ? 40.103  3.706   34.572  1.00 32.39  ? 139 PHE F O   1 
ATOM   12497 C  CB  . PHE F 1 139 ? 40.169  5.180   31.762  1.00 23.06  ? 139 PHE F CB  1 
ATOM   12498 C  CG  . PHE F 1 139 ? 41.562  4.587   31.872  1.00 23.71  ? 139 PHE F CG  1 
ATOM   12499 C  CD1 . PHE F 1 139 ? 41.759  3.229   32.074  1.00 26.79  ? 139 PHE F CD1 1 
ATOM   12500 C  CD2 . PHE F 1 139 ? 42.682  5.418   31.799  1.00 26.28  ? 139 PHE F CD2 1 
ATOM   12501 C  CE1 . PHE F 1 139 ? 43.050  2.720   32.157  1.00 31.17  ? 139 PHE F CE1 1 
ATOM   12502 C  CE2 . PHE F 1 139 ? 43.965  4.912   31.872  1.00 27.44  ? 139 PHE F CE2 1 
ATOM   12503 C  CZ  . PHE F 1 139 ? 44.148  3.556   32.022  1.00 30.37  ? 139 PHE F CZ  1 
ATOM   12504 N  N   . LYS F 1 140 ? 37.968  3.800   33.797  1.00 34.05  ? 140 LYS F N   1 
ATOM   12505 C  CA  . LYS F 1 140 ? 37.505  2.664   34.590  1.00 40.52  ? 140 LYS F CA  1 
ATOM   12506 C  C   . LYS F 1 140 ? 37.812  1.464   33.739  1.00 28.74  ? 140 LYS F C   1 
ATOM   12507 O  O   . LYS F 1 140 ? 37.720  1.601   32.547  1.00 25.25  ? 140 LYS F O   1 
ATOM   12508 C  CB  . LYS F 1 140 ? 36.018  2.768   35.014  1.00 58.39  ? 140 LYS F CB  1 
ATOM   12509 C  CG  . LYS F 1 140 ? 35.686  2.251   36.465  1.00 74.47  ? 140 LYS F CG  1 
ATOM   12510 C  CD  . LYS F 1 140 ? 36.507  2.669   37.709  1.00 77.37  ? 140 LYS F CD  1 
ATOM   12511 C  CE  . LYS F 1 140 ? 36.876  1.560   38.761  1.00 74.84  ? 140 LYS F CE  1 
ATOM   12512 N  NZ  . LYS F 1 140 ? 36.026  1.425   39.982  1.00 48.16  ? 140 LYS F NZ  1 
ATOM   12513 N  N   . TYR F 1 141 ? 38.302  0.368   34.319  1.00 28.10  ? 141 TYR F N   1 
ATOM   12514 C  CA  . TYR F 1 141 ? 38.370  -0.907  33.623  1.00 35.33  ? 141 TYR F CA  1 
ATOM   12515 C  C   . TYR F 1 141 ? 36.983  -1.516  33.444  1.00 54.84  ? 141 TYR F C   1 
ATOM   12516 O  O   . TYR F 1 141 ? 35.998  -1.063  34.039  1.00 58.29  ? 141 TYR F O   1 
ATOM   12517 C  CB  . TYR F 1 141 ? 39.201  -1.908  34.375  1.00 37.81  ? 141 TYR F CB  1 
ATOM   12518 C  CG  . TYR F 1 141 ? 40.657  -1.762  33.981  1.00 38.05  ? 141 TYR F CG  1 
ATOM   12519 C  CD1 . TYR F 1 141 ? 41.141  -2.411  32.861  1.00 43.83  ? 141 TYR F CD1 1 
ATOM   12520 C  CD2 . TYR F 1 141 ? 41.512  -1.030  34.707  1.00 38.70  ? 141 TYR F CD2 1 
ATOM   12521 C  CE1 . TYR F 1 141 ? 42.446  -2.332  32.463  1.00 41.88  ? 141 TYR F CE1 1 
ATOM   12522 C  CE2 . TYR F 1 141 ? 42.839  -0.937  34.326  1.00 59.55  ? 141 TYR F CE2 1 
ATOM   12523 C  CZ  . TYR F 1 141 ? 43.311  -1.601  33.216  1.00 52.65  ? 141 TYR F CZ  1 
ATOM   12524 O  OH  . TYR F 1 141 ? 44.621  -1.509  32.862  1.00 67.81  ? 141 TYR F OH  1 
ATOM   12525 N  N   . PHE F 1 142 ? 36.845  -2.489  32.554  1.00 59.04  ? 142 PHE F N   1 
ATOM   12526 C  CA  . PHE F 1 142 ? 35.499  -2.633  32.005  1.00 74.45  ? 142 PHE F CA  1 
ATOM   12527 C  C   . PHE F 1 142 ? 34.643  -3.249  33.126  1.00 58.12  ? 142 PHE F C   1 
ATOM   12528 O  O   . PHE F 1 142 ? 33.421  -3.074  33.014  1.00 81.12  ? 142 PHE F O   1 
ATOM   12529 C  CB  . PHE F 1 142 ? 35.393  -3.243  30.576  1.00 94.61  ? 142 PHE F CB  1 
ATOM   12530 C  CG  . PHE F 1 142 ? 35.491  -4.766  30.563  1.00 114.84 ? 142 PHE F CG  1 
ATOM   12531 C  CD1 . PHE F 1 142 ? 36.746  -5.393  30.598  1.00 113.71 ? 142 PHE F CD1 1 
ATOM   12532 C  CD2 . PHE F 1 142 ? 34.323  -5.556  30.637  1.00 91.62  ? 142 PHE F CD2 1 
ATOM   12533 C  CE1 . PHE F 1 142 ? 36.820  -6.776  30.692  1.00 127.84 ? 142 PHE F CE1 1 
ATOM   12534 C  CE2 . PHE F 1 142 ? 34.397  -6.938  30.727  1.00 87.63  ? 142 PHE F CE2 1 
ATOM   12535 C  CZ  . PHE F 1 142 ? 35.640  -7.544  30.751  1.00 121.46 ? 142 PHE F CZ  1 
ATOM   12536 N  N   . ASP F 1 143 ? 35.218  -3.952  34.161  1.00 36.19  ? 143 ASP F N   1 
ATOM   12537 C  CA  . ASP F 1 143 ? 34.344  -4.587  35.152  1.00 31.95  ? 143 ASP F CA  1 
ATOM   12538 C  C   . ASP F 1 143 ? 34.583  -4.036  36.529  1.00 28.96  ? 143 ASP F C   1 
ATOM   12539 O  O   . ASP F 1 143 ? 34.608  -4.734  37.528  1.00 28.55  ? 143 ASP F O   1 
ATOM   12540 C  CB  . ASP F 1 143 ? 34.119  -6.083  35.088  1.00 37.72  ? 143 ASP F CB  1 
ATOM   12541 C  CG  . ASP F 1 143 ? 35.223  -7.043  35.496  1.00 50.04  ? 143 ASP F CG  1 
ATOM   12542 O  OD1 . ASP F 1 143 ? 36.376  -6.805  35.077  1.00 44.91  ? 143 ASP F OD1 1 
ATOM   12543 O  OD2 . ASP F 1 143 ? 34.870  -8.067  36.172  1.00 50.44  ? 143 ASP F OD2 1 
ATOM   12544 N  N   . GLU F 1 144 ? 34.661  -2.720  36.557  1.00 28.09  ? 144 GLU F N   1 
ATOM   12545 C  CA  . GLU F 1 144 ? 34.940  -1.925  37.741  1.00 29.45  ? 144 GLU F CA  1 
ATOM   12546 C  C   . GLU F 1 144 ? 36.240  -2.331  38.455  1.00 28.55  ? 144 GLU F C   1 
ATOM   12547 O  O   . GLU F 1 144 ? 36.375  -2.056  39.657  1.00 28.93  ? 144 GLU F O   1 
ATOM   12548 C  CB  . GLU F 1 144 ? 33.721  -1.981  38.659  1.00 31.79  ? 144 GLU F CB  1 
ATOM   12549 C  CG  . GLU F 1 144 ? 32.442  -1.399  38.044  1.00 35.98  ? 144 GLU F CG  1 
ATOM   12550 C  CD  . GLU F 1 144 ? 32.490  0.075   37.699  1.00 32.64  ? 144 GLU F CD  1 
ATOM   12551 O  OE1 . GLU F 1 144 ? 33.324  0.733   38.312  1.00 28.45  ? 144 GLU F OE1 1 
ATOM   12552 O  OE2 . GLU F 1 144 ? 31.805  0.527   36.772  1.00 37.53  ? 144 GLU F OE2 1 
ATOM   12553 N  N   . ARG F 1 145 ? 37.213  -2.912  37.723  1.00 26.68  ? 145 ARG F N   1 
ATOM   12554 C  CA  . ARG F 1 145 ? 38.493  -3.307  38.317  1.00 30.08  ? 145 ARG F CA  1 
ATOM   12555 C  C   . ARG F 1 145 ? 39.473  -2.138  38.404  1.00 28.26  ? 145 ARG F C   1 
ATOM   12556 O  O   . ARG F 1 145 ? 39.293  -1.087  37.764  1.00 29.56  ? 145 ARG F O   1 
ATOM   12557 C  CB  . ARG F 1 145 ? 39.046  -4.540  37.610  1.00 32.07  ? 145 ARG F CB  1 
ATOM   12558 C  CG  . ARG F 1 145 ? 38.096  -5.693  37.915  1.00 30.37  ? 145 ARG F CG  1 
ATOM   12559 C  CD  . ARG F 1 145 ? 38.662  -6.975  37.479  1.00 30.76  ? 145 ARG F CD  1 
ATOM   12560 N  NE  . ARG F 1 145 ? 37.741  -8.103  37.563  1.00 34.46  ? 145 ARG F NE  1 
ATOM   12561 C  CZ  . ARG F 1 145 ? 37.527  -8.851  38.666  1.00 34.44  ? 145 ARG F CZ  1 
ATOM   12562 N  NH1 . ARG F 1 145 ? 38.361  -8.863  39.687  1.00 30.00  ? 145 ARG F NH1 1 
ATOM   12563 N  NH2 . ARG F 1 145 ? 36.460  -9.608  38.723  1.00 33.82  ? 145 ARG F NH2 1 
ATOM   12564 N  N   . ASP F 1 146 ? 40.384  -2.254  39.379  1.00 27.09  ? 146 ASP F N   1 
ATOM   12565 C  CA  . ASP F 1 146 ? 41.492  -1.314  39.489  1.00 26.76  ? 146 ASP F CA  1 
ATOM   12566 C  C   . ASP F 1 146 ? 42.733  -1.983  38.890  1.00 25.30  ? 146 ASP F C   1 
ATOM   12567 O  O   . ASP F 1 146 ? 42.702  -3.086  38.303  1.00 21.10  ? 146 ASP F O   1 
ATOM   12568 C  CB  . ASP F 1 146 ? 41.653  -0.770  40.891  1.00 28.20  ? 146 ASP F CB  1 
ATOM   12569 C  CG  . ASP F 1 146 ? 41.948  -1.830  41.942  1.00 27.16  ? 146 ASP F CG  1 
ATOM   12570 O  OD1 . ASP F 1 146 ? 42.480  -2.897  41.567  1.00 23.11  ? 146 ASP F OD1 1 
ATOM   12571 O  OD2 . ASP F 1 146 ? 41.557  -1.580  43.105  1.00 31.60  ? 146 ASP F OD2 1 
ATOM   12572 N  N   . MET F 1 147 ? 43.813  -1.229  38.999  1.00 27.57  ? 147 MET F N   1 
ATOM   12573 C  CA  . MET F 1 147 ? 45.075  -1.577  38.392  1.00 27.33  ? 147 MET F CA  1 
ATOM   12574 C  C   . MET F 1 147 ? 45.631  -2.838  39.038  1.00 24.35  ? 147 MET F C   1 
ATOM   12575 O  O   . MET F 1 147 ? 46.405  -3.510  38.416  1.00 24.19  ? 147 MET F O   1 
ATOM   12576 C  CB  . MET F 1 147 ? 45.955  -0.337  38.519  1.00 34.07  ? 147 MET F CB  1 
ATOM   12577 C  CG  . MET F 1 147 ? 47.041  -0.263  37.551  1.00 39.70  ? 147 MET F CG  1 
ATOM   12578 S  SD  . MET F 1 147 ? 46.322  -0.211  35.922  1.00 38.09  ? 147 MET F SD  1 
ATOM   12579 C  CE  . MET F 1 147 ? 46.396  1.503   35.429  1.00 49.29  ? 147 MET F CE  1 
ATOM   12580 N  N   . LEU F 1 148 ? 45.250  -3.187  40.278  1.00 26.59  ? 148 LEU F N   1 
ATOM   12581 C  CA  . LEU F 1 148 ? 45.686  -4.436  40.923  1.00 25.19  ? 148 LEU F CA  1 
ATOM   12582 C  C   . LEU F 1 148 ? 44.804  -5.608  40.511  1.00 27.27  ? 148 LEU F C   1 
ATOM   12583 O  O   . LEU F 1 148 ? 45.066  -6.723  40.965  1.00 25.44  ? 148 LEU F O   1 
ATOM   12584 C  CB  . LEU F 1 148 ? 45.649  -4.321  42.444  1.00 23.76  ? 148 LEU F CB  1 
ATOM   12585 C  CG  . LEU F 1 148 ? 46.520  -3.214  43.043  1.00 28.10  ? 148 LEU F CG  1 
ATOM   12586 C  CD1 . LEU F 1 148 ? 46.362  -3.148  44.544  1.00 29.68  ? 148 LEU F CD1 1 
ATOM   12587 C  CD2 . LEU F 1 148 ? 47.982  -3.348  42.695  1.00 31.59  ? 148 LEU F CD2 1 
ATOM   12588 N  N   . GLY F 1 149 ? 43.750  -5.374  39.677  1.00 23.68  ? 149 GLY F N   1 
ATOM   12589 C  CA  . GLY F 1 149 ? 42.936  -6.476  39.180  1.00 21.34  ? 149 GLY F CA  1 
ATOM   12590 C  C   . GLY F 1 149 ? 41.736  -6.842  40.049  1.00 21.80  ? 149 GLY F C   1 
ATOM   12591 O  O   . GLY F 1 149 ? 41.004  -7.819  39.839  1.00 20.91  ? 149 GLY F O   1 
ATOM   12592 N  N   . PHE F 1 150 ? 41.470  -6.010  41.036  1.00 24.99  ? 150 PHE F N   1 
ATOM   12593 C  CA  . PHE F 1 150 ? 40.394  -6.252  41.990  1.00 24.86  ? 150 PHE F CA  1 
ATOM   12594 C  C   . PHE F 1 150 ? 39.263  -5.300  41.677  1.00 22.52  ? 150 PHE F C   1 
ATOM   12595 O  O   . PHE F 1 150 ? 39.515  -4.165  41.312  1.00 23.31  ? 150 PHE F O   1 
ATOM   12596 C  CB  . PHE F 1 150 ? 40.877  -6.094  43.440  1.00 25.05  ? 150 PHE F CB  1 
ATOM   12597 C  CG  . PHE F 1 150 ? 41.589  -7.350  43.935  1.00 24.55  ? 150 PHE F CG  1 
ATOM   12598 C  CD1 . PHE F 1 150 ? 42.822  -7.708  43.440  1.00 27.81  ? 150 PHE F CD1 1 
ATOM   12599 C  CD2 . PHE F 1 150 ? 41.002  -8.205  44.872  1.00 27.68  ? 150 PHE F CD2 1 
ATOM   12600 C  CE1 . PHE F 1 150 ? 43.461  -8.891  43.883  1.00 26.82  ? 150 PHE F CE1 1 
ATOM   12601 C  CE2 . PHE F 1 150 ? 41.622  -9.382  45.300  1.00 25.19  ? 150 PHE F CE2 1 
ATOM   12602 C  CZ  . PHE F 1 150 ? 42.882  -9.693  44.836  1.00 26.25  ? 150 PHE F CZ  1 
ATOM   12603 N  N   . VAL F 1 151 ? 38.039  -5.781  41.861  1.00 19.77  ? 151 VAL F N   1 
ATOM   12604 C  CA  . VAL F 1 151 ? 36.893  -4.906  41.781  1.00 21.87  ? 151 VAL F CA  1 
ATOM   12605 C  C   . VAL F 1 151 ? 37.008  -3.868  42.903  1.00 25.30  ? 151 VAL F C   1 
ATOM   12606 O  O   . VAL F 1 151 ? 37.322  -4.209  44.054  1.00 30.46  ? 151 VAL F O   1 
ATOM   12607 C  CB  . VAL F 1 151 ? 35.573  -5.701  41.912  1.00 22.65  ? 151 VAL F CB  1 
ATOM   12608 C  CG1 . VAL F 1 151 ? 34.369  -4.791  41.839  1.00 25.03  ? 151 VAL F CG1 1 
ATOM   12609 C  CG2 . VAL F 1 151 ? 35.409  -6.807  40.908  1.00 21.96  ? 151 VAL F CG2 1 
ATOM   12610 N  N   . ASP F 1 152 ? 36.656  -2.623  42.578  1.00 28.63  ? 152 ASP F N   1 
ATOM   12611 C  CA  . ASP F 1 152 ? 36.956  -1.462  43.416  1.00 33.69  ? 152 ASP F CA  1 
ATOM   12612 C  C   . ASP F 1 152 ? 35.688  -0.610  43.458  1.00 30.45  ? 152 ASP F C   1 
ATOM   12613 O  O   . ASP F 1 152 ? 35.216  -0.151  42.406  1.00 29.85  ? 152 ASP F O   1 
ATOM   12614 C  CB  . ASP F 1 152 ? 38.163  -0.749  42.836  1.00 32.77  ? 152 ASP F CB  1 
ATOM   12615 C  CG  . ASP F 1 152 ? 38.782  0.352   43.665  1.00 42.12  ? 152 ASP F CG  1 
ATOM   12616 O  OD1 . ASP F 1 152 ? 37.908  1.167   44.146  1.00 33.49  ? 152 ASP F OD1 1 
ATOM   12617 O  OD2 . ASP F 1 152 ? 40.127  0.448   43.640  1.00 31.90  ? 152 ASP F OD2 1 
ATOM   12618 N  N   . GLY F 1 153 ? 35.086  -0.507  44.652  1.00 26.50  ? 153 GLY F N   1 
ATOM   12619 C  CA  . GLY F 1 153 ? 33.845  0.238   44.824  1.00 26.67  ? 153 GLY F CA  1 
ATOM   12620 C  C   . GLY F 1 153 ? 32.703  -0.539  45.513  1.00 25.37  ? 153 GLY F C   1 
ATOM   12621 O  O   . GLY F 1 153 ? 31.750  0.084   45.976  1.00 26.48  ? 153 GLY F O   1 
ATOM   12622 N  N   . THR F 1 154 ? 32.807  -1.872  45.569  1.00 23.62  ? 154 THR F N   1 
ATOM   12623 C  CA  . THR F 1 154 ? 31.782  -2.792  46.023  1.00 22.70  ? 154 THR F CA  1 
ATOM   12624 C  C   . THR F 1 154 ? 31.105  -2.344  47.321  1.00 23.75  ? 154 THR F C   1 
ATOM   12625 O  O   . THR F 1 154 ? 29.901  -2.374  47.437  1.00 24.18  ? 154 THR F O   1 
ATOM   12626 C  CB  . THR F 1 154 ? 32.425  -4.129  46.262  1.00 20.90  ? 154 THR F CB  1 
ATOM   12627 O  OG1 . THR F 1 154 ? 33.162  -4.395  45.084  1.00 20.83  ? 154 THR F OG1 1 
ATOM   12628 C  CG2 . THR F 1 154 ? 31.371  -5.179  46.436  1.00 23.00  ? 154 THR F CG2 1 
ATOM   12629 N  N   . GLU F 1 155 ? 31.858  -1.938  48.320  1.00 23.36  ? 155 GLU F N   1 
ATOM   12630 C  CA  . GLU F 1 155 ? 31.279  -1.686  49.621  1.00 22.49  ? 155 GLU F CA  1 
ATOM   12631 C  C   . GLU F 1 155 ? 31.016  -0.214  49.790  1.00 19.83  ? 155 GLU F C   1 
ATOM   12632 O  O   . GLU F 1 155 ? 30.685  0.198   50.866  1.00 21.65  ? 155 GLU F O   1 
ATOM   12633 C  CB  . GLU F 1 155 ? 32.160  -2.199  50.760  1.00 23.90  ? 155 GLU F CB  1 
ATOM   12634 C  CG  . GLU F 1 155 ? 32.095  -3.719  50.896  1.00 25.29  ? 155 GLU F CG  1 
ATOM   12635 C  CD  . GLU F 1 155 ? 30.731  -4.160  51.358  1.00 27.16  ? 155 GLU F CD  1 
ATOM   12636 O  OE1 . GLU F 1 155 ? 30.391  -3.768  52.515  1.00 35.99  ? 155 GLU F OE1 1 
ATOM   12637 O  OE2 . GLU F 1 155 ? 30.067  -4.915  50.592  1.00 34.90  ? 155 GLU F OE2 1 
ATOM   12638 N  N   . ASN F 1 156 ? 31.060  0.590   48.761  1.00 21.08  ? 156 ASN F N   1 
ATOM   12639 C  CA  . ASN F 1 156 ? 30.695  1.971   48.962  1.00 23.54  ? 156 ASN F CA  1 
ATOM   12640 C  C   . ASN F 1 156 ? 29.281  2.047   49.503  1.00 25.04  ? 156 ASN F C   1 
ATOM   12641 O  O   . ASN F 1 156 ? 28.512  1.193   49.165  1.00 26.97  ? 156 ASN F O   1 
ATOM   12642 C  CB  . ASN F 1 156 ? 30.688  2.773   47.689  1.00 24.52  ? 156 ASN F CB  1 
ATOM   12643 C  CG  . ASN F 1 156 ? 31.998  3.465   47.490  1.00 27.27  ? 156 ASN F CG  1 
ATOM   12644 O  OD1 . ASN F 1 156 ? 32.656  3.894   48.454  1.00 30.19  ? 156 ASN F OD1 1 
ATOM   12645 N  ND2 . ASN F 1 156 ? 32.385  3.557   46.233  1.00 26.69  ? 156 ASN F ND2 1 
ATOM   12646 N  N   . PRO F 1 157 ? 28.891  3.065   50.295  1.00 24.39  ? 157 PRO F N   1 
ATOM   12647 C  CA  . PRO F 1 157 ? 27.493  3.249   50.673  1.00 26.17  ? 157 PRO F CA  1 
ATOM   12648 C  C   . PRO F 1 157 ? 26.682  3.776   49.500  1.00 29.60  ? 157 PRO F C   1 
ATOM   12649 O  O   . PRO F 1 157 ? 27.225  4.416   48.629  1.00 33.41  ? 157 PRO F O   1 
ATOM   12650 C  CB  . PRO F 1 157 ? 27.592  4.272   51.843  1.00 25.93  ? 157 PRO F CB  1 
ATOM   12651 C  CG  . PRO F 1 157 ? 28.804  5.091   51.480  1.00 26.12  ? 157 PRO F CG  1 
ATOM   12652 C  CD  . PRO F 1 157 ? 29.772  4.050   50.932  1.00 27.01  ? 157 PRO F CD  1 
ATOM   12653 N  N   . THR F 1 158 ? 25.376  3.570   49.581  1.00 34.30  ? 158 THR F N   1 
ATOM   12654 C  CA  . THR F 1 158 ? 24.330  3.860   48.613  1.00 39.18  ? 158 THR F CA  1 
ATOM   12655 C  C   . THR F 1 158 ? 23.214  4.723   49.195  1.00 41.19  ? 158 THR F C   1 
ATOM   12656 O  O   . THR F 1 158 ? 22.939  4.560   50.376  1.00 35.53  ? 158 THR F O   1 
ATOM   12657 C  CB  . THR F 1 158 ? 23.701  2.475   48.442  1.00 37.43  ? 158 THR F CB  1 
ATOM   12658 O  OG1 . THR F 1 158 ? 24.454  2.151   47.315  1.00 33.11  ? 158 THR F OG1 1 
ATOM   12659 C  CG2 . THR F 1 158 ? 22.238  2.440   48.083  1.00 45.89  ? 158 THR F CG2 1 
ATOM   12660 N  N   . GLY F 1 159 ? 22.515  5.494   48.342  1.00 38.29  ? 159 GLY F N   1 
ATOM   12661 C  CA  . GLY F 1 159 ? 21.283  6.171   48.710  1.00 38.29  ? 159 GLY F CA  1 
ATOM   12662 C  C   . GLY F 1 159 ? 21.370  6.910   50.044  1.00 42.15  ? 159 GLY F C   1 
ATOM   12663 O  O   . GLY F 1 159 ? 22.256  7.710   50.245  1.00 42.83  ? 159 GLY F O   1 
ATOM   12664 N  N   . ALA F 1 160 ? 20.449  6.638   50.968  1.00 43.74  ? 160 ALA F N   1 
ATOM   12665 C  CA  . ALA F 1 160 ? 20.346  7.457   52.156  1.00 43.00  ? 160 ALA F CA  1 
ATOM   12666 C  C   . ALA F 1 160 ? 21.594  7.241   53.024  1.00 40.87  ? 160 ALA F C   1 
ATOM   12667 O  O   . ALA F 1 160 ? 22.103  8.177   53.657  1.00 29.32  ? 160 ALA F O   1 
ATOM   12668 C  CB  . ALA F 1 160 ? 19.060  7.154   52.879  1.00 38.73  ? 160 ALA F CB  1 
ATOM   12669 N  N   . ALA F 1 161 ? 22.156  6.025   53.018  1.00 44.23  ? 161 ALA F N   1 
ATOM   12670 C  CA  . ALA F 1 161 ? 23.348  5.760   53.833  1.00 46.39  ? 161 ALA F CA  1 
ATOM   12671 C  C   . ALA F 1 161 ? 24.533  6.605   53.343  1.00 45.79  ? 161 ALA F C   1 
ATOM   12672 O  O   . ALA F 1 161 ? 25.348  7.081   54.149  1.00 37.75  ? 161 ALA F O   1 
ATOM   12673 C  CB  . ALA F 1 161 ? 23.703  4.288   53.819  1.00 38.76  ? 161 ALA F CB  1 
ATOM   12674 N  N   . ALA F 1 162 ? 24.598  6.785   52.008  1.00 38.25  ? 162 ALA F N   1 
ATOM   12675 C  CA  . ALA F 1 162 ? 25.621  7.621   51.428  1.00 38.92  ? 162 ALA F CA  1 
ATOM   12676 C  C   . ALA F 1 162 ? 25.413  9.087   51.805  1.00 33.39  ? 162 ALA F C   1 
ATOM   12677 O  O   . ALA F 1 162 ? 26.410  9.677   52.238  1.00 27.66  ? 162 ALA F O   1 
ATOM   12678 C  CB  . ALA F 1 162 ? 25.698  7.410   49.967  1.00 35.69  ? 162 ALA F CB  1 
ATOM   12679 N  N   . ARG F 1 163 ? 24.179  9.631   51.597  1.00 35.15  ? 163 ARG F N   1 
ATOM   12680 C  CA  . ARG F 1 163 ? 23.812  11.004  51.952  1.00 37.23  ? 163 ARG F CA  1 
ATOM   12681 C  C   . ARG F 1 163 ? 24.308  11.208  53.405  1.00 38.13  ? 163 ARG F C   1 
ATOM   12682 O  O   . ARG F 1 163 ? 24.960  12.199  53.726  1.00 39.02  ? 163 ARG F O   1 
ATOM   12683 C  CB  . ARG F 1 163 ? 22.328  11.426  51.699  1.00 43.97  ? 163 ARG F CB  1 
ATOM   12684 C  CG  . ARG F 1 163 ? 21.555  11.704  50.385  1.00 37.94  ? 163 ARG F CG  1 
ATOM   12685 N  N   . ARG F 1 164 ? 24.083  10.240  54.309  1.00 38.47  ? 164 ARG F N   1 
ATOM   12686 C  CA  . ARG F 1 164 ? 24.367  10.452  55.718  1.00 43.11  ? 164 ARG F CA  1 
ATOM   12687 C  C   . ARG F 1 164 ? 25.866  10.389  55.954  1.00 36.14  ? 164 ARG F C   1 
ATOM   12688 O  O   . ARG F 1 164 ? 26.363  11.115  56.776  1.00 39.23  ? 164 ARG F O   1 
ATOM   12689 C  CB  . ARG F 1 164 ? 23.612  9.518   56.672  1.00 67.77  ? 164 ARG F CB  1 
ATOM   12690 C  CG  . ARG F 1 164 ? 23.055  10.178  57.938  1.00 101.25 ? 164 ARG F CG  1 
ATOM   12691 C  CD  . ARG F 1 164 ? 22.080  9.272   58.741  1.00 101.66 ? 164 ARG F CD  1 
ATOM   12692 N  NE  . ARG F 1 164 ? 22.788  8.012   59.035  1.00 107.32 ? 164 ARG F NE  1 
ATOM   12693 C  CZ  . ARG F 1 164 ? 22.667  6.803   58.437  1.00 88.46  ? 164 ARG F CZ  1 
ATOM   12694 N  NH1 . ARG F 1 164 ? 23.576  5.869   58.718  1.00 72.02  ? 164 ARG F NH1 1 
ATOM   12695 N  NH2 . ARG F 1 164 ? 21.691  6.537   57.553  1.00 66.85  ? 164 ARG F NH2 1 
ATOM   12696 N  N   . ALA F 1 165 ? 26.620  9.571   55.229  1.00 31.52  ? 165 ALA F N   1 
ATOM   12697 C  CA  . ALA F 1 165 ? 28.048  9.460   55.505  1.00 27.95  ? 165 ALA F CA  1 
ATOM   12698 C  C   . ALA F 1 165 ? 28.884  10.601  54.904  1.00 24.88  ? 165 ALA F C   1 
ATOM   12699 O  O   . ALA F 1 165 ? 29.952  10.862  55.387  1.00 25.00  ? 165 ALA F O   1 
ATOM   12700 C  CB  . ALA F 1 165 ? 28.563  8.162   55.002  1.00 26.09  ? 165 ALA F CB  1 
ATOM   12701 N  N   . VAL F 1 166 ? 28.376  11.310  53.896  1.00 27.80  ? 166 VAL F N   1 
ATOM   12702 C  CA  . VAL F 1 166 ? 29.163  12.235  53.084  1.00 28.15  ? 166 VAL F CA  1 
ATOM   12703 C  C   . VAL F 1 166 ? 28.836  13.703  53.342  1.00 28.03  ? 166 VAL F C   1 
ATOM   12704 O  O   . VAL F 1 166 ? 29.715  14.520  53.209  1.00 32.73  ? 166 VAL F O   1 
ATOM   12705 C  CB  . VAL F 1 166 ? 28.818  11.842  51.637  1.00 31.10  ? 166 VAL F CB  1 
ATOM   12706 C  CG1 . VAL F 1 166 ? 28.789  13.004  50.649  1.00 33.95  ? 166 VAL F CG1 1 
ATOM   12707 C  CG2 . VAL F 1 166 ? 29.633  10.628  51.226  1.00 31.63  ? 166 VAL F CG2 1 
ATOM   12708 N  N   . LEU F 1 167 ? 27.587  14.059  53.618  1.00 24.27  ? 167 LEU F N   1 
ATOM   12709 C  CA  . LEU F 1 167 ? 27.186  15.449  53.622  1.00 27.35  ? 167 LEU F CA  1 
ATOM   12710 C  C   . LEU F 1 167 ? 27.172  16.025  55.035  1.00 29.78  ? 167 LEU F C   1 
ATOM   12711 O  O   . LEU F 1 167 ? 26.645  15.416  55.973  1.00 28.56  ? 167 LEU F O   1 
ATOM   12712 C  CB  . LEU F 1 167 ? 25.810  15.593  52.998  1.00 26.37  ? 167 LEU F CB  1 
ATOM   12713 C  CG  . LEU F 1 167 ? 25.685  15.170  51.541  1.00 30.00  ? 167 LEU F CG  1 
ATOM   12714 C  CD1 . LEU F 1 167 ? 24.281  15.408  51.115  1.00 29.89  ? 167 LEU F CD1 1 
ATOM   12715 C  CD2 . LEU F 1 167 ? 26.609  16.029  50.744  1.00 31.77  ? 167 LEU F CD2 1 
ATOM   12716 N  N   . VAL F 1 168 ? 27.776  17.219  55.155  1.00 28.66  ? 168 VAL F N   1 
ATOM   12717 C  CA  . VAL F 1 168 ? 27.734  17.975  56.378  1.00 27.56  ? 168 VAL F CA  1 
ATOM   12718 C  C   . VAL F 1 168 ? 26.272  18.261  56.663  1.00 30.73  ? 168 VAL F C   1 
ATOM   12719 O  O   . VAL F 1 168 ? 25.562  18.664  55.737  1.00 29.28  ? 168 VAL F O   1 
ATOM   12720 C  CB  . VAL F 1 168 ? 28.552  19.266  56.264  1.00 28.87  ? 168 VAL F CB  1 
ATOM   12721 C  CG1 . VAL F 1 168 ? 28.389  20.192  57.477  1.00 27.90  ? 168 VAL F CG1 1 
ATOM   12722 C  CG2 . VAL F 1 168 ? 30.023  18.936  56.037  1.00 33.24  ? 168 VAL F CG2 1 
ATOM   12723 N  N   . GLY F 1 169 ? 25.860  18.046  57.940  1.00 32.91  ? 169 GLY F N   1 
ATOM   12724 C  CA  . GLY F 1 169 ? 24.519  18.424  58.367  1.00 34.09  ? 169 GLY F CA  1 
ATOM   12725 C  C   . GLY F 1 169 ? 24.537  19.494  59.466  1.00 41.13  ? 169 GLY F C   1 
ATOM   12726 O  O   . GLY F 1 169 ? 25.306  20.479  59.416  1.00 39.95  ? 169 GLY F O   1 
ATOM   12727 N  N   . ALA F 1 170 ? 23.639  19.331  60.469  1.00 54.02  ? 170 ALA F N   1 
ATOM   12728 C  CA  . ALA F 1 170 ? 23.401  20.383  61.474  1.00 46.11  ? 170 ALA F CA  1 
ATOM   12729 C  C   . ALA F 1 170 ? 24.557  20.459  62.505  1.00 40.28  ? 170 ALA F C   1 
ATOM   12730 O  O   . ALA F 1 170 ? 24.666  21.452  63.188  1.00 46.76  ? 170 ALA F O   1 
ATOM   12731 C  CB  . ALA F 1 170 ? 22.017  20.262  62.053  1.00 40.18  ? 170 ALA F CB  1 
ATOM   12732 N  N   . GLU F 1 171 ? 25.531  19.549  62.499  1.00 33.25  ? 171 GLU F N   1 
ATOM   12733 C  CA  . GLU F 1 171 ? 26.775  19.730  63.237  1.00 35.21  ? 171 GLU F CA  1 
ATOM   12734 C  C   . GLU F 1 171 ? 27.610  20.911  62.739  1.00 34.21  ? 171 GLU F C   1 
ATOM   12735 O  O   . GLU F 1 171 ? 28.527  21.287  63.428  1.00 35.44  ? 171 GLU F O   1 
ATOM   12736 C  CB  . GLU F 1 171 ? 27.656  18.464  63.313  1.00 36.90  ? 171 GLU F CB  1 
ATOM   12737 C  CG  . GLU F 1 171 ? 28.451  18.046  62.072  1.00 35.85  ? 171 GLU F CG  1 
ATOM   12738 C  CD  . GLU F 1 171 ? 27.711  17.487  60.874  1.00 39.68  ? 171 GLU F CD  1 
ATOM   12739 O  OE1 . GLU F 1 171 ? 26.480  17.415  60.909  1.00 42.25  ? 171 GLU F OE1 1 
ATOM   12740 O  OE2 . GLU F 1 171 ? 28.350  17.211  59.845  1.00 42.58  ? 171 GLU F OE2 1 
ATOM   12741 N  N   . ASP F 1 172 ? 27.367  21.458  61.551  1.00 34.19  ? 172 ASP F N   1 
ATOM   12742 C  CA  . ASP F 1 172 ? 28.124  22.615  61.075  1.00 36.96  ? 172 ASP F CA  1 
ATOM   12743 C  C   . ASP F 1 172 ? 27.227  23.348  60.089  1.00 39.15  ? 172 ASP F C   1 
ATOM   12744 O  O   . ASP F 1 172 ? 27.486  23.403  58.900  1.00 37.95  ? 172 ASP F O   1 
ATOM   12745 C  CB  . ASP F 1 172 ? 29.493  22.261  60.501  1.00 37.18  ? 172 ASP F CB  1 
ATOM   12746 C  CG  . ASP F 1 172 ? 30.475  23.422  60.327  1.00 36.20  ? 172 ASP F CG  1 
ATOM   12747 O  OD1 . ASP F 1 172 ? 30.106  24.564  60.708  1.00 34.55  ? 172 ASP F OD1 1 
ATOM   12748 O  OD2 . ASP F 1 172 ? 31.582  23.191  59.777  1.00 31.68  ? 172 ASP F OD2 1 
ATOM   12749 N  N   . PRO F 1 173 ? 26.132  23.936  60.600  1.00 41.69  ? 173 PRO F N   1 
ATOM   12750 C  CA  . PRO F 1 173 ? 24.964  24.317  59.782  1.00 42.87  ? 173 PRO F CA  1 
ATOM   12751 C  C   . PRO F 1 173 ? 25.193  25.372  58.713  1.00 39.58  ? 173 PRO F C   1 
ATOM   12752 O  O   . PRO F 1 173 ? 24.498  25.424  57.714  1.00 35.03  ? 173 PRO F O   1 
ATOM   12753 C  CB  . PRO F 1 173 ? 23.953  24.902  60.782  1.00 43.97  ? 173 PRO F CB  1 
ATOM   12754 C  CG  . PRO F 1 173 ? 24.498  24.431  62.108  1.00 47.80  ? 173 PRO F CG  1 
ATOM   12755 C  CD  . PRO F 1 173 ? 26.007  24.297  62.020  1.00 44.17  ? 173 PRO F CD  1 
ATOM   12756 N  N   . ALA F 1 174 ? 26.158  26.256  58.934  1.00 39.56  ? 174 ALA F N   1 
ATOM   12757 C  CA  . ALA F 1 174 ? 26.489  27.210  57.879  1.00 33.81  ? 174 ALA F CA  1 
ATOM   12758 C  C   . ALA F 1 174 ? 27.052  26.494  56.636  1.00 36.12  ? 174 ALA F C   1 
ATOM   12759 O  O   . ALA F 1 174 ? 27.059  27.061  55.556  1.00 35.21  ? 174 ALA F O   1 
ATOM   12760 C  CB  . ALA F 1 174 ? 27.488  28.191  58.429  1.00 29.93  ? 174 ALA F CB  1 
ATOM   12761 N  N   . PHE F 1 175 ? 27.542  25.249  56.769  1.00 30.89  ? 175 PHE F N   1 
ATOM   12762 C  CA  . PHE F 1 175 ? 28.194  24.533  55.684  1.00 32.42  ? 175 PHE F CA  1 
ATOM   12763 C  C   . PHE F 1 175 ? 27.465  23.221  55.376  1.00 33.27  ? 175 PHE F C   1 
ATOM   12764 O  O   . PHE F 1 175 ? 27.984  22.407  54.640  1.00 32.77  ? 175 PHE F O   1 
ATOM   12765 C  CB  . PHE F 1 175 ? 29.667  24.278  56.043  1.00 34.93  ? 175 PHE F CB  1 
ATOM   12766 C  CG  . PHE F 1 175 ? 30.435  25.579  56.141  1.00 35.77  ? 175 PHE F CG  1 
ATOM   12767 C  CD1 . PHE F 1 175 ? 30.645  26.365  55.026  1.00 39.18  ? 175 PHE F CD1 1 
ATOM   12768 C  CD2 . PHE F 1 175 ? 30.859  26.058  57.370  1.00 40.93  ? 175 PHE F CD2 1 
ATOM   12769 C  CE1 . PHE F 1 175 ? 31.291  27.579  55.148  1.00 40.32  ? 175 PHE F CE1 1 
ATOM   12770 C  CE2 . PHE F 1 175 ? 31.488  27.291  57.487  1.00 40.54  ? 175 PHE F CE2 1 
ATOM   12771 C  CZ  . PHE F 1 175 ? 31.710  28.043  56.376  1.00 38.44  ? 175 PHE F CZ  1 
ATOM   12772 N  N   . ALA F 1 176 ? 26.249  23.032  55.878  1.00 26.68  ? 176 ALA F N   1 
ATOM   12773 C  CA  . ALA F 1 176 ? 25.443  21.899  55.485  1.00 26.06  ? 176 ALA F CA  1 
ATOM   12774 C  C   . ALA F 1 176 ? 25.348  21.739  53.984  1.00 23.00  ? 176 ALA F C   1 
ATOM   12775 O  O   . ALA F 1 176 ? 25.201  22.694  53.214  1.00 28.39  ? 176 ALA F O   1 
ATOM   12776 C  CB  . ALA F 1 176 ? 24.083  22.076  56.056  1.00 28.04  ? 176 ALA F CB  1 
ATOM   12777 N  N   . GLY F 1 177 ? 25.492  20.483  53.554  1.00 25.55  ? 177 GLY F N   1 
ATOM   12778 C  CA  . GLY F 1 177 ? 25.501  20.192  52.120  1.00 26.78  ? 177 GLY F CA  1 
ATOM   12779 C  C   . GLY F 1 177 ? 26.894  20.131  51.485  1.00 26.14  ? 177 GLY F C   1 
ATOM   12780 O  O   . GLY F 1 177 ? 27.022  19.816  50.326  1.00 28.37  ? 177 GLY F O   1 
ATOM   12781 N  N   . GLY F 1 178 ? 27.912  20.478  52.252  1.00 26.86  ? 178 GLY F N   1 
ATOM   12782 C  CA  . GLY F 1 178 ? 29.299  20.326  51.849  1.00 26.50  ? 178 GLY F CA  1 
ATOM   12783 C  C   . GLY F 1 178 ? 29.812  18.924  52.151  1.00 25.57  ? 178 GLY F C   1 
ATOM   12784 O  O   . GLY F 1 178 ? 29.090  18.082  52.646  1.00 26.84  ? 178 GLY F O   1 
ATOM   12785 N  N   . SER F 1 179 ? 31.054  18.683  51.787  1.00 22.84  ? 179 SER F N   1 
ATOM   12786 C  CA  . SER F 1 179 ? 31.704  17.445  52.100  1.00 21.97  ? 179 SER F CA  1 
ATOM   12787 C  C   . SER F 1 179 ? 33.222  17.673  52.173  1.00 24.16  ? 179 SER F C   1 
ATOM   12788 O  O   . SER F 1 179 ? 33.728  18.747  51.820  1.00 23.11  ? 179 SER F O   1 
ATOM   12789 C  CB  . SER F 1 179 ? 31.305  16.385  51.061  1.00 22.50  ? 179 SER F CB  1 
ATOM   12790 O  OG  . SER F 1 179 ? 31.772  15.103  51.497  1.00 23.08  ? 179 SER F OG  1 
ATOM   12791 N  N   . TYR F 1 180 ? 33.946  16.667  52.666  1.00 22.01  ? 180 TYR F N   1 
ATOM   12792 C  CA  . TYR F 1 180 ? 35.377  16.773  52.745  1.00 22.95  ? 180 TYR F CA  1 
ATOM   12793 C  C   . TYR F 1 180 ? 35.968  15.690  51.847  1.00 23.52  ? 180 TYR F C   1 
ATOM   12794 O  O   . TYR F 1 180 ? 35.655  14.521  52.001  1.00 27.58  ? 180 TYR F O   1 
ATOM   12795 C  CB  . TYR F 1 180 ? 35.923  16.618  54.173  1.00 23.28  ? 180 TYR F CB  1 
ATOM   12796 C  CG  . TYR F 1 180 ? 35.543  17.751  55.105  1.00 24.15  ? 180 TYR F CG  1 
ATOM   12797 C  CD1 . TYR F 1 180 ? 34.328  17.745  55.755  1.00 27.65  ? 180 TYR F CD1 1 
ATOM   12798 C  CD2 . TYR F 1 180 ? 36.401  18.799  55.350  1.00 27.21  ? 180 TYR F CD2 1 
ATOM   12799 C  CE1 . TYR F 1 180 ? 33.945  18.764  56.608  1.00 29.93  ? 180 TYR F CE1 1 
ATOM   12800 C  CE2 . TYR F 1 180 ? 36.043  19.828  56.206  1.00 25.56  ? 180 TYR F CE2 1 
ATOM   12801 C  CZ  . TYR F 1 180 ? 34.816  19.815  56.840  1.00 29.91  ? 180 TYR F CZ  1 
ATOM   12802 O  OH  . TYR F 1 180 ? 34.386  20.858  57.648  1.00 30.80  ? 180 TYR F OH  1 
ATOM   12803 N  N   . ALA F 1 181 ? 36.881  16.114  50.961  1.00 25.53  ? 181 ALA F N   1 
ATOM   12804 C  CA  . ALA F 1 181 ? 37.588  15.213  50.078  1.00 29.14  ? 181 ALA F CA  1 
ATOM   12805 C  C   . ALA F 1 181 ? 39.072  15.120  50.422  1.00 26.66  ? 181 ALA F C   1 
ATOM   12806 O  O   . ALA F 1 181 ? 39.738  16.134  50.561  1.00 27.59  ? 181 ALA F O   1 
ATOM   12807 C  CB  . ALA F 1 181 ? 37.405  15.661  48.644  1.00 27.50  ? 181 ALA F CB  1 
ATOM   12808 N  N   . VAL F 1 182 ? 39.563  13.888  50.427  1.00 23.94  ? 182 VAL F N   1 
ATOM   12809 C  CA  . VAL F 1 182 ? 40.968  13.570  50.545  1.00 23.18  ? 182 VAL F CA  1 
ATOM   12810 C  C   . VAL F 1 182 ? 41.397  12.916  49.248  1.00 24.86  ? 182 VAL F C   1 
ATOM   12811 O  O   . VAL F 1 182 ? 40.747  11.993  48.786  1.00 24.28  ? 182 VAL F O   1 
ATOM   12812 C  CB  . VAL F 1 182 ? 41.253  12.630  51.728  1.00 26.17  ? 182 VAL F CB  1 
ATOM   12813 C  CG1 . VAL F 1 182 ? 42.662  12.064  51.738  1.00 28.43  ? 182 VAL F CG1 1 
ATOM   12814 C  CG2 . VAL F 1 182 ? 40.967  13.288  53.070  1.00 29.90  ? 182 VAL F CG2 1 
ATOM   12815 N  N   . VAL F 1 183 ? 42.518  13.391  48.688  1.00 26.61  ? 183 VAL F N   1 
ATOM   12816 C  CA  . VAL F 1 183 ? 43.063  12.827  47.465  1.00 24.07  ? 183 VAL F CA  1 
ATOM   12817 C  C   . VAL F 1 183 ? 44.455  12.312  47.781  1.00 25.33  ? 183 VAL F C   1 
ATOM   12818 O  O   . VAL F 1 183 ? 45.174  12.917  48.568  1.00 22.09  ? 183 VAL F O   1 
ATOM   12819 C  CB  . VAL F 1 183 ? 43.085  13.768  46.251  1.00 23.64  ? 183 VAL F CB  1 
ATOM   12820 C  CG1 . VAL F 1 183 ? 41.687  14.180  45.868  1.00 23.98  ? 183 VAL F CG1 1 
ATOM   12821 C  CG2 . VAL F 1 183 ? 43.902  14.991  46.528  1.00 21.72  ? 183 VAL F CG2 1 
ATOM   12822 N  N   . GLN F 1 184 ? 44.800  11.175  47.166  1.00 24.93  ? 184 GLN F N   1 
ATOM   12823 C  CA  . GLN F 1 184 ? 46.166  10.685  47.140  1.00 23.83  ? 184 GLN F CA  1 
ATOM   12824 C  C   . GLN F 1 184 ? 46.415  9.981   45.808  1.00 25.28  ? 184 GLN F C   1 
ATOM   12825 O  O   . GLN F 1 184 ? 45.669  9.095   45.418  1.00 23.26  ? 184 GLN F O   1 
ATOM   12826 C  CB  . GLN F 1 184 ? 46.398  9.640   48.248  1.00 26.56  ? 184 GLN F CB  1 
ATOM   12827 C  CG  . GLN F 1 184 ? 46.332  10.137  49.696  1.00 24.30  ? 184 GLN F CG  1 
ATOM   12828 C  CD  . GLN F 1 184 ? 46.600  8.951   50.595  1.00 26.61  ? 184 GLN F CD  1 
ATOM   12829 O  OE1 . GLN F 1 184 ? 45.849  7.977   50.578  1.00 24.62  ? 184 GLN F OE1 1 
ATOM   12830 N  NE2 . GLN F 1 184 ? 47.753  8.924   51.244  1.00 26.35  ? 184 GLN F NE2 1 
ATOM   12831 N  N   . LYS F 1 185 ? 47.490  10.342  45.105  1.00 25.46  ? 185 LYS F N   1 
ATOM   12832 C  CA  . LYS F 1 185 ? 47.864  9.654   43.894  1.00 25.07  ? 185 LYS F CA  1 
ATOM   12833 C  C   . LYS F 1 185 ? 48.803  8.522   44.256  1.00 22.98  ? 185 LYS F C   1 
ATOM   12834 O  O   . LYS F 1 185 ? 49.779  8.771   44.929  1.00 22.21  ? 185 LYS F O   1 
ATOM   12835 C  CB  . LYS F 1 185 ? 48.503  10.675  42.956  1.00 25.30  ? 185 LYS F CB  1 
ATOM   12836 C  CG  . LYS F 1 185 ? 48.936  10.040  41.664  1.00 28.95  ? 185 LYS F CG  1 
ATOM   12837 C  CD  . LYS F 1 185 ? 49.106  10.955  40.465  1.00 30.90  ? 185 LYS F CD  1 
ATOM   12838 C  CE  . LYS F 1 185 ? 50.308  11.733  40.585  1.00 32.69  ? 185 LYS F CE  1 
ATOM   12839 N  NZ  . LYS F 1 185 ? 50.437  12.538  39.382  1.00 33.91  ? 185 LYS F NZ  1 
ATOM   12840 N  N   . TYR F 1 186 ? 48.489  7.300   43.822  1.00 22.88  ? 186 TYR F N   1 
ATOM   12841 C  CA  . TYR F 1 186 ? 49.248  6.114   44.193  1.00 21.79  ? 186 TYR F CA  1 
ATOM   12842 C  C   . TYR F 1 186 ? 49.849  5.531   42.947  1.00 21.70  ? 186 TYR F C   1 
ATOM   12843 O  O   . TYR F 1 186 ? 49.162  5.459   41.946  1.00 28.89  ? 186 TYR F O   1 
ATOM   12844 C  CB  . TYR F 1 186 ? 48.447  4.984   44.861  1.00 21.64  ? 186 TYR F CB  1 
ATOM   12845 C  CG  . TYR F 1 186 ? 48.160  5.191   46.359  1.00 23.11  ? 186 TYR F CG  1 
ATOM   12846 C  CD1 . TYR F 1 186 ? 47.003  5.884   46.766  1.00 24.92  ? 186 TYR F CD1 1 
ATOM   12847 C  CD2 . TYR F 1 186 ? 49.009  4.733   47.370  1.00 20.61  ? 186 TYR F CD2 1 
ATOM   12848 C  CE1 . TYR F 1 186 ? 46.672  6.115   48.086  1.00 24.17  ? 186 TYR F CE1 1 
ATOM   12849 C  CE2 . TYR F 1 186 ? 48.685  4.956   48.690  1.00 21.57  ? 186 TYR F CE2 1 
ATOM   12850 C  CZ  . TYR F 1 186 ? 47.527  5.647   49.060  1.00 25.80  ? 186 TYR F CZ  1 
ATOM   12851 O  OH  . TYR F 1 186 ? 47.125  5.904   50.347  1.00 23.86  ? 186 TYR F OH  1 
ATOM   12852 N  N   . LEU F 1 187 ? 51.114  5.111   43.022  1.00 24.17  ? 187 LEU F N   1 
ATOM   12853 C  CA  . LEU F 1 187 ? 51.732  4.356   41.938  1.00 24.37  ? 187 LEU F CA  1 
ATOM   12854 C  C   . LEU F 1 187 ? 52.036  2.956   42.419  1.00 24.51  ? 187 LEU F C   1 
ATOM   12855 O  O   . LEU F 1 187 ? 52.499  2.767   43.543  1.00 28.89  ? 187 LEU F O   1 
ATOM   12856 C  CB  . LEU F 1 187 ? 53.027  5.057   41.539  1.00 25.22  ? 187 LEU F CB  1 
ATOM   12857 C  CG  . LEU F 1 187 ? 52.870  6.456   40.922  1.00 32.11  ? 187 LEU F CG  1 
ATOM   12858 C  CD1 . LEU F 1 187 ? 54.211  7.047   40.655  1.00 35.80  ? 187 LEU F CD1 1 
ATOM   12859 C  CD2 . LEU F 1 187 ? 52.084  6.460   39.604  1.00 35.09  ? 187 LEU F CD2 1 
ATOM   12860 N  N   . HIS F 1 188 ? 51.799  1.977   41.578  1.00 22.08  ? 188 HIS F N   1 
ATOM   12861 C  CA  . HIS F 1 188 ? 51.900  0.596   41.991  1.00 22.58  ? 188 HIS F CA  1 
ATOM   12862 C  C   . HIS F 1 188 ? 53.184  -0.040  41.486  1.00 23.92  ? 188 HIS F C   1 
ATOM   12863 O  O   . HIS F 1 188 ? 53.651  0.273   40.446  1.00 23.49  ? 188 HIS F O   1 
ATOM   12864 C  CB  . HIS F 1 188 ? 50.693  -0.221  41.506  1.00 23.97  ? 188 HIS F CB  1 
ATOM   12865 C  CG  . HIS F 1 188 ? 49.430  0.215   42.160  1.00 26.34  ? 188 HIS F CG  1 
ATOM   12866 N  ND1 . HIS F 1 188 ? 49.191  0.049   43.503  1.00 32.43  ? 188 HIS F ND1 1 
ATOM   12867 C  CD2 . HIS F 1 188 ? 48.354  0.842   41.701  1.00 28.52  ? 188 HIS F CD2 1 
ATOM   12868 C  CE1 . HIS F 1 188 ? 48.012  0.557   43.820  1.00 31.69  ? 188 HIS F CE1 1 
ATOM   12869 N  NE2 . HIS F 1 188 ? 47.475  1.041   42.743  1.00 30.83  ? 188 HIS F NE2 1 
ATOM   12870 N  N   . ASP F 1 189 ? 53.690  -1.022  42.215  1.00 26.24  ? 189 ASP F N   1 
ATOM   12871 C  CA  . ASP F 1 189 ? 54.731  -1.905  41.764  1.00 25.04  ? 189 ASP F CA  1 
ATOM   12872 C  C   . ASP F 1 189 ? 54.062  -3.165  41.236  1.00 27.80  ? 189 ASP F C   1 
ATOM   12873 O  O   . ASP F 1 189 ? 53.827  -4.159  41.915  1.00 23.84  ? 189 ASP F O   1 
ATOM   12874 C  CB  . ASP F 1 189 ? 55.702  -2.183  42.892  1.00 27.24  ? 189 ASP F CB  1 
ATOM   12875 C  CG  . ASP F 1 189 ? 56.925  -2.970  42.484  1.00 27.34  ? 189 ASP F CG  1 
ATOM   12876 O  OD1 . ASP F 1 189 ? 56.953  -3.539  41.383  1.00 29.09  ? 189 ASP F OD1 1 
ATOM   12877 O  OD2 . ASP F 1 189 ? 57.812  -3.051  43.309  1.00 33.72  ? 189 ASP F OD2 1 
ATOM   12878 N  N   . ILE F 1 190 ? 53.763  -3.106  39.956  1.00 29.27  ? 190 ILE F N   1 
ATOM   12879 C  CA  . ILE F 1 190 ? 53.039  -4.158  39.277  1.00 29.88  ? 190 ILE F CA  1 
ATOM   12880 C  C   . ILE F 1 190 ? 53.910  -5.391  39.179  1.00 27.57  ? 190 ILE F C   1 
ATOM   12881 O  O   . ILE F 1 190 ? 53.377  -6.466  39.341  1.00 27.46  ? 190 ILE F O   1 
ATOM   12882 C  CB  . ILE F 1 190 ? 52.545  -3.617  37.928  1.00 31.78  ? 190 ILE F CB  1 
ATOM   12883 C  CG1 . ILE F 1 190 ? 51.439  -2.566  38.181  1.00 35.21  ? 190 ILE F CG1 1 
ATOM   12884 C  CG2 . ILE F 1 190 ? 52.087  -4.730  36.990  1.00 31.18  ? 190 ILE F CG2 1 
ATOM   12885 C  CD1 . ILE F 1 190 ? 50.156  -3.151  38.701  1.00 38.94  ? 190 ILE F CD1 1 
ATOM   12886 N  N   . ASP F 1 191 ? 55.246  -5.241  39.010  1.00 31.89  ? 191 ASP F N   1 
ATOM   12887 C  CA  . ASP F 1 191 ? 56.123  -6.400  38.869  1.00 33.86  ? 191 ASP F CA  1 
ATOM   12888 C  C   . ASP F 1 191 ? 56.083  -7.210  40.152  1.00 30.02  ? 191 ASP F C   1 
ATOM   12889 O  O   . ASP F 1 191 ? 55.788  -8.398  40.152  1.00 27.06  ? 191 ASP F O   1 
ATOM   12890 C  CB  . ASP F 1 191 ? 57.524  -6.011  38.456  1.00 40.38  ? 191 ASP F CB  1 
ATOM   12891 C  CG  . ASP F 1 191 ? 57.615  -5.513  37.011  1.00 47.83  ? 191 ASP F CG  1 
ATOM   12892 O  OD1 . ASP F 1 191 ? 57.054  -6.166  36.109  1.00 57.68  ? 191 ASP F OD1 1 
ATOM   12893 O  OD2 . ASP F 1 191 ? 58.278  -4.494  36.746  1.00 62.17  ? 191 ASP F OD2 1 
ATOM   12894 N  N   . ALA F 1 192 ? 56.248  -6.515  41.260  1.00 27.24  ? 192 ALA F N   1 
ATOM   12895 C  CA  . ALA F 1 192 ? 56.161  -7.199  42.531  1.00 29.27  ? 192 ALA F CA  1 
ATOM   12896 C  C   . ALA F 1 192 ? 54.809  -7.882  42.728  1.00 30.92  ? 192 ALA F C   1 
ATOM   12897 O  O   . ALA F 1 192 ? 54.757  -8.971  43.286  1.00 26.82  ? 192 ALA F O   1 
ATOM   12898 C  CB  . ALA F 1 192 ? 56.398  -6.194  43.665  1.00 32.63  ? 192 ALA F CB  1 
ATOM   12899 N  N   . TRP F 1 193 ? 53.718  -7.140  42.453  1.00 30.55  ? 193 TRP F N   1 
ATOM   12900 C  CA  . TRP F 1 193 ? 52.365  -7.592  42.718  1.00 31.60  ? 193 TRP F CA  1 
ATOM   12901 C  C   . TRP F 1 193 ? 52.047  -8.851  41.913  1.00 28.60  ? 193 TRP F C   1 
ATOM   12902 O  O   . TRP F 1 193 ? 51.424  -9.776  42.419  1.00 26.76  ? 193 TRP F O   1 
ATOM   12903 C  CB  . TRP F 1 193 ? 51.412  -6.453  42.357  1.00 33.39  ? 193 TRP F CB  1 
ATOM   12904 C  CG  . TRP F 1 193 ? 49.944  -6.786  42.505  1.00 36.73  ? 193 TRP F CG  1 
ATOM   12905 C  CD1 . TRP F 1 193 ? 49.010  -6.908  41.517  1.00 33.14  ? 193 TRP F CD1 1 
ATOM   12906 C  CD2 . TRP F 1 193 ? 49.235  -6.992  43.745  1.00 31.51  ? 193 TRP F CD2 1 
ATOM   12907 N  NE1 . TRP F 1 193 ? 47.780  -7.132  42.058  1.00 27.39  ? 193 TRP F NE1 1 
ATOM   12908 C  CE2 . TRP F 1 193 ? 47.890  -7.206  43.413  1.00 26.46  ? 193 TRP F CE2 1 
ATOM   12909 C  CE3 . TRP F 1 193 ? 49.627  -7.028  45.078  1.00 25.43  ? 193 TRP F CE3 1 
ATOM   12910 C  CZ2 . TRP F 1 193 ? 46.919  -7.431  44.364  1.00 27.24  ? 193 TRP F CZ2 1 
ATOM   12911 C  CZ3 . TRP F 1 193 ? 48.655  -7.208  46.010  1.00 27.97  ? 193 TRP F CZ3 1 
ATOM   12912 C  CH2 . TRP F 1 193 ? 47.312  -7.378  45.661  1.00 29.38  ? 193 TRP F CH2 1 
ATOM   12913 N  N   . GLU F 1 194 ? 52.528  -8.875  40.667  1.00 33.53  ? 194 GLU F N   1 
ATOM   12914 C  CA  . GLU F 1 194 ? 52.285  -9.992  39.764  1.00 34.78  ? 194 GLU F CA  1 
ATOM   12915 C  C   . GLU F 1 194 ? 53.175  -11.172 40.115  1.00 35.82  ? 194 GLU F C   1 
ATOM   12916 O  O   . GLU F 1 194 ? 52.931  -12.270 39.683  1.00 37.79  ? 194 GLU F O   1 
ATOM   12917 C  CB  . GLU F 1 194 ? 52.246  -9.580  38.302  1.00 35.38  ? 194 GLU F CB  1 
ATOM   12918 C  CG  . GLU F 1 194 ? 50.810  -9.225  37.930  1.00 46.85  ? 194 GLU F CG  1 
ATOM   12919 C  CD  . GLU F 1 194 ? 50.703  -8.447  36.630  1.00 68.11  ? 194 GLU F CD  1 
ATOM   12920 O  OE1 . GLU F 1 194 ? 51.594  -8.547  35.735  1.00 79.16  ? 194 GLU F OE1 1 
ATOM   12921 O  OE2 . GLU F 1 194 ? 49.706  -7.713  36.517  1.00 71.45  ? 194 GLU F OE2 1 
ATOM   12922 N  N   . GLY F 1 195 ? 54.134  -11.018 41.012  1.00 37.24  ? 195 GLY F N   1 
ATOM   12923 C  CA  . GLY F 1 195 ? 54.838  -12.206 41.472  1.00 34.48  ? 195 GLY F CA  1 
ATOM   12924 C  C   . GLY F 1 195 ? 54.088  -12.934 42.571  1.00 32.12  ? 195 GLY F C   1 
ATOM   12925 O  O   . GLY F 1 195 ? 54.462  -14.028 42.927  1.00 33.82  ? 195 GLY F O   1 
ATOM   12926 N  N   . LEU F 1 196 ? 53.082  -12.320 43.172  1.00 34.25  ? 196 LEU F N   1 
ATOM   12927 C  CA  . LEU F 1 196 ? 52.255  -13.007 44.167  1.00 33.87  ? 196 LEU F CA  1 
ATOM   12928 C  C   . LEU F 1 196 ? 51.254  -13.938 43.467  1.00 35.46  ? 196 LEU F C   1 
ATOM   12929 O  O   . LEU F 1 196 ? 50.705  -13.623 42.404  1.00 36.38  ? 196 LEU F O   1 
ATOM   12930 C  CB  . LEU F 1 196 ? 51.470  -12.028 45.023  1.00 34.54  ? 196 LEU F CB  1 
ATOM   12931 C  CG  . LEU F 1 196 ? 52.112  -11.567 46.333  1.00 41.70  ? 196 LEU F CG  1 
ATOM   12932 C  CD1 . LEU F 1 196 ? 53.458  -11.031 45.998  1.00 48.41  ? 196 LEU F CD1 1 
ATOM   12933 C  CD2 . LEU F 1 196 ? 51.243  -10.494 47.037  1.00 40.96  ? 196 LEU F CD2 1 
ATOM   12934 N  N   . SER F 1 197 ? 50.954  -15.056 44.115  1.00 32.44  ? 197 SER F N   1 
ATOM   12935 C  CA  . SER F 1 197 ? 49.865  -15.912 43.666  1.00 32.27  ? 197 SER F CA  1 
ATOM   12936 C  C   . SER F 1 197 ? 48.550  -15.161 43.863  1.00 28.66  ? 197 SER F C   1 
ATOM   12937 O  O   . SER F 1 197 ? 48.465  -14.242 44.681  1.00 33.60  ? 197 SER F O   1 
ATOM   12938 C  CB  . SER F 1 197 ? 49.852  -17.225 44.456  1.00 28.54  ? 197 SER F CB  1 
ATOM   12939 O  OG  . SER F 1 197 ? 49.492  -16.908 45.792  1.00 27.16  ? 197 SER F OG  1 
ATOM   12940 N  N   . VAL F 1 198 ? 47.498  -15.608 43.172  1.00 28.69  ? 198 VAL F N   1 
ATOM   12941 C  CA  . VAL F 1 198 ? 46.182  -15.027 43.408  1.00 31.13  ? 198 VAL F CA  1 
ATOM   12942 C  C   . VAL F 1 198 ? 45.819  -15.141 44.896  1.00 37.69  ? 198 VAL F C   1 
ATOM   12943 O  O   . VAL F 1 198 ? 45.280  -14.174 45.442  1.00 30.99  ? 198 VAL F O   1 
ATOM   12944 C  CB  . VAL F 1 198 ? 45.102  -15.631 42.495  1.00 28.85  ? 198 VAL F CB  1 
ATOM   12945 C  CG1 . VAL F 1 198 ? 43.720  -15.199 42.949  1.00 30.93  ? 198 VAL F CG1 1 
ATOM   12946 C  CG2 . VAL F 1 198 ? 45.357  -15.242 41.038  1.00 26.95  ? 198 VAL F CG2 1 
ATOM   12947 N  N   . GLU F 1 199 ? 46.121  -16.295 45.565  1.00 34.25  ? 199 GLU F N   1 
ATOM   12948 C  CA  . GLU F 1 199 ? 45.671  -16.485 46.924  1.00 35.06  ? 199 GLU F CA  1 
ATOM   12949 C  C   . GLU F 1 199 ? 46.371  -15.448 47.802  1.00 30.56  ? 199 GLU F C   1 
ATOM   12950 O  O   . GLU F 1 199 ? 45.740  -14.863 48.677  1.00 26.61  ? 199 GLU F O   1 
ATOM   12951 C  CB  . GLU F 1 199 ? 45.756  -17.945 47.380  1.00 44.89  ? 199 GLU F CB  1 
ATOM   12952 C  CG  . GLU F 1 199 ? 44.856  -18.230 48.591  1.00 65.17  ? 199 GLU F CG  1 
ATOM   12953 C  CD  . GLU F 1 199 ? 44.997  -19.571 49.335  1.00 75.36  ? 199 GLU F CD  1 
ATOM   12954 O  OE1 . GLU F 1 199 ? 46.161  -19.915 49.683  1.00 67.84  ? 199 GLU F OE1 1 
ATOM   12955 O  OE2 . GLU F 1 199 ? 43.975  -20.284 49.588  1.00 69.72  ? 199 GLU F OE2 1 
ATOM   12956 N  N   . ALA F 1 200 ? 47.655  -15.156 47.539  1.00 26.04  ? 200 ALA F N   1 
ATOM   12957 C  CA  . ALA F 1 200 ? 48.383  -14.176 48.334  1.00 22.51  ? 200 ALA F CA  1 
ATOM   12958 C  C   . ALA F 1 200 ? 47.874  -12.758 48.101  1.00 25.23  ? 200 ALA F C   1 
ATOM   12959 O  O   . ALA F 1 200 ? 47.874  -11.919 49.024  1.00 27.93  ? 200 ALA F O   1 
ATOM   12960 C  CB  . ALA F 1 200 ? 49.825  -14.216 47.987  1.00 22.97  ? 200 ALA F CB  1 
ATOM   12961 N  N   . GLN F 1 201 ? 47.476  -12.461 46.856  1.00 24.20  ? 201 GLN F N   1 
ATOM   12962 C  CA  . GLN F 1 201 ? 46.859  -11.166 46.602  1.00 27.52  ? 201 GLN F CA  1 
ATOM   12963 C  C   . GLN F 1 201 ? 45.544  -11.015 47.370  1.00 24.76  ? 201 GLN F C   1 
ATOM   12964 O  O   . GLN F 1 201 ? 45.225  -9.955  47.891  1.00 21.77  ? 201 GLN F O   1 
ATOM   12965 C  CB  . GLN F 1 201 ? 46.617  -11.031 45.104  1.00 27.90  ? 201 GLN F CB  1 
ATOM   12966 C  CG  . GLN F 1 201 ? 47.889  -10.881 44.296  1.00 28.55  ? 201 GLN F CG  1 
ATOM   12967 C  CD  . GLN F 1 201 ? 47.566  -10.729 42.833  1.00 27.42  ? 201 GLN F CD  1 
ATOM   12968 O  OE1 . GLN F 1 201 ? 46.414  -10.852 42.414  1.00 29.21  ? 201 GLN F OE1 1 
ATOM   12969 N  NE2 . GLN F 1 201 ? 48.575  -10.439 42.042  1.00 26.86  ? 201 GLN F NE2 1 
ATOM   12970 N  N   . GLU F 1 202 ? 44.758  -12.098 47.404  1.00 26.05  ? 202 GLU F N   1 
ATOM   12971 C  CA  . GLU F 1 202 ? 43.480  -12.089 48.095  1.00 27.35  ? 202 GLU F CA  1 
ATOM   12972 C  C   . GLU F 1 202 ? 43.678  -11.797 49.582  1.00 27.31  ? 202 GLU F C   1 
ATOM   12973 O  O   . GLU F 1 202 ? 42.854  -11.139 50.208  1.00 26.39  ? 202 GLU F O   1 
ATOM   12974 C  CB  . GLU F 1 202 ? 42.752  -13.408 47.870  1.00 30.87  ? 202 GLU F CB  1 
ATOM   12975 C  CG  . GLU F 1 202 ? 42.137  -13.547 46.487  1.00 28.78  ? 202 GLU F CG  1 
ATOM   12976 C  CD  . GLU F 1 202 ? 41.592  -14.921 46.105  1.00 28.98  ? 202 GLU F CD  1 
ATOM   12977 O  OE1 . GLU F 1 202 ? 41.970  -15.944 46.738  1.00 30.26  ? 202 GLU F OE1 1 
ATOM   12978 O  OE2 . GLU F 1 202 ? 40.794  -14.995 45.120  1.00 29.12  ? 202 GLU F OE2 1 
ATOM   12979 N  N   . ARG F 1 203 ? 44.812  -12.263 50.105  1.00 30.16  ? 203 ARG F N   1 
ATOM   12980 C  CA  . ARG F 1 203 ? 45.143  -12.067 51.492  1.00 32.53  ? 203 ARG F CA  1 
ATOM   12981 C  C   . ARG F 1 203 ? 45.549  -10.619 51.756  1.00 33.62  ? 203 ARG F C   1 
ATOM   12982 O  O   . ARG F 1 203 ? 45.326  -10.109 52.867  1.00 35.34  ? 203 ARG F O   1 
ATOM   12983 C  CB  . ARG F 1 203 ? 46.211  -13.059 51.961  1.00 36.78  ? 203 ARG F CB  1 
ATOM   12984 C  CG  . ARG F 1 203 ? 45.647  -14.406 52.394  1.00 42.43  ? 203 ARG F CG  1 
ATOM   12985 C  CD  . ARG F 1 203 ? 46.789  -15.414 52.659  1.00 52.27  ? 203 ARG F CD  1 
ATOM   12986 N  NE  . ARG F 1 203 ? 46.126  -16.660 52.267  1.00 78.93  ? 203 ARG F NE  1 
ATOM   12987 C  CZ  . ARG F 1 203 ? 45.289  -17.407 53.030  1.00 94.94  ? 203 ARG F CZ  1 
ATOM   12988 N  NH1 . ARG F 1 203 ? 45.565  -17.661 54.310  1.00 72.37  ? 203 ARG F NH1 1 
ATOM   12989 N  NH2 . ARG F 1 203 ? 44.255  -18.020 52.452  1.00 96.69  ? 203 ARG F NH2 1 
ATOM   12990 N  N   . VAL F 1 204 ? 46.173  -9.952  50.783  1.00 29.22  ? 204 VAL F N   1 
ATOM   12991 C  CA  . VAL F 1 204 ? 46.486  -8.525  50.939  1.00 25.53  ? 204 VAL F CA  1 
ATOM   12992 C  C   . VAL F 1 204 ? 45.204  -7.674  50.944  1.00 27.34  ? 204 VAL F C   1 
ATOM   12993 O  O   . VAL F 1 204 ? 45.068  -6.749  51.758  1.00 29.65  ? 204 VAL F O   1 
ATOM   12994 C  CB  . VAL F 1 204 ? 47.430  -8.130  49.800  1.00 26.09  ? 204 VAL F CB  1 
ATOM   12995 C  CG1 . VAL F 1 204 ? 47.641  -6.632  49.692  1.00 26.31  ? 204 VAL F CG1 1 
ATOM   12996 C  CG2 . VAL F 1 204 ? 48.746  -8.861  49.906  1.00 27.55  ? 204 VAL F CG2 1 
ATOM   12997 N  N   . ILE F 1 205 ? 44.254  -7.967  50.032  1.00 28.33  ? 205 ILE F N   1 
ATOM   12998 C  CA  . ILE F 1 205 ? 43.067  -7.137  49.877  1.00 26.31  ? 205 ILE F CA  1 
ATOM   12999 C  C   . ILE F 1 205 ? 42.024  -7.521  50.930  1.00 27.17  ? 205 ILE F C   1 
ATOM   13000 O  O   . ILE F 1 205 ? 41.476  -6.645  51.613  1.00 24.49  ? 205 ILE F O   1 
ATOM   13001 C  CB  . ILE F 1 205 ? 42.498  -7.263  48.455  1.00 27.35  ? 205 ILE F CB  1 
ATOM   13002 C  CG1 . ILE F 1 205 ? 43.513  -6.843  47.396  1.00 31.21  ? 205 ILE F CG1 1 
ATOM   13003 C  CG2 . ILE F 1 205 ? 41.202  -6.469  48.313  1.00 29.15  ? 205 ILE F CG2 1 
ATOM   13004 C  CD1 . ILE F 1 205 ? 43.884  -5.377  47.498  1.00 30.93  ? 205 ILE F CD1 1 
ATOM   13005 N  N   . GLY F 1 206 ? 41.707  -8.824  51.019  1.00 24.53  ? 206 GLY F N   1 
ATOM   13006 C  CA  . GLY F 1 206 ? 40.683  -9.235  51.964  1.00 26.04  ? 206 GLY F CA  1 
ATOM   13007 C  C   . GLY F 1 206 ? 39.426  -9.720  51.256  1.00 30.62  ? 206 GLY F C   1 
ATOM   13008 O  O   . GLY F 1 206 ? 38.423  -9.973  51.919  1.00 35.09  ? 206 GLY F O   1 
ATOM   13009 N  N   . ARG F 1 207 ? 39.479  -9.856  49.911  1.00 30.38  ? 207 ARG F N   1 
ATOM   13010 C  CA  . ARG F 1 207 ? 38.323  -10.320 49.146  1.00 25.93  ? 207 ARG F CA  1 
ATOM   13011 C  C   . ARG F 1 207 ? 38.835  -11.246 48.076  1.00 24.17  ? 207 ARG F C   1 
ATOM   13012 O  O   . ARG F 1 207 ? 40.028  -11.239 47.784  1.00 26.94  ? 207 ARG F O   1 
ATOM   13013 C  CB  . ARG F 1 207 ? 37.569  -9.203  48.447  1.00 23.23  ? 207 ARG F CB  1 
ATOM   13014 C  CG  . ARG F 1 207 ? 37.207  -8.088  49.403  1.00 27.43  ? 207 ARG F CG  1 
ATOM   13015 C  CD  . ARG F 1 207 ? 36.480  -6.910  48.756  1.00 28.12  ? 207 ARG F CD  1 
ATOM   13016 N  NE  . ARG F 1 207 ? 35.149  -7.330  48.327  1.00 26.54  ? 207 ARG F NE  1 
ATOM   13017 C  CZ  . ARG F 1 207 ? 34.094  -7.304  49.071  1.00 26.39  ? 207 ARG F CZ  1 
ATOM   13018 N  NH1 . ARG F 1 207 ? 33.065  -8.001  48.685  1.00 23.92  ? 207 ARG F NH1 1 
ATOM   13019 N  NH2 . ARG F 1 207 ? 34.051  -6.572  50.163  1.00 27.28  ? 207 ARG F NH2 1 
ATOM   13020 N  N   . ARG F 1 208 ? 37.936  -12.042 47.506  1.00 29.24  ? 208 ARG F N   1 
ATOM   13021 C  CA  . ARG F 1 208 ? 38.265  -12.980 46.421  1.00 29.47  ? 208 ARG F CA  1 
ATOM   13022 C  C   . ARG F 1 208 ? 38.473  -12.175 45.146  1.00 27.46  ? 208 ARG F C   1 
ATOM   13023 O  O   . ARG F 1 208 ? 37.709  -11.263 44.893  1.00 28.80  ? 208 ARG F O   1 
ATOM   13024 C  CB  . ARG F 1 208 ? 37.180  -14.049 46.155  1.00 33.74  ? 208 ARG F CB  1 
ATOM   13025 C  CG  . ARG F 1 208 ? 36.914  -14.976 47.336  1.00 43.91  ? 208 ARG F CG  1 
ATOM   13026 C  CD  . ARG F 1 208 ? 38.139  -15.719 47.900  1.00 53.02  ? 208 ARG F CD  1 
ATOM   13027 N  NE  . ARG F 1 208 ? 38.592  -16.672 46.866  1.00 84.03  ? 208 ARG F NE  1 
ATOM   13028 C  CZ  . ARG F 1 208 ? 37.905  -17.795 46.467  1.00 70.08  ? 208 ARG F CZ  1 
ATOM   13029 N  NH1 . ARG F 1 208 ? 36.850  -18.194 47.143  1.00 79.25  ? 208 ARG F NH1 1 
ATOM   13030 N  NH2 . ARG F 1 208 ? 38.278  -18.581 45.466  1.00 47.32  ? 208 ARG F NH2 1 
ATOM   13031 N  N   . LYS F 1 209 ? 39.433  -12.557 44.307  1.00 26.06  ? 209 LYS F N   1 
ATOM   13032 C  CA  . LYS F 1 209 ? 39.774  -11.726 43.175  1.00 27.70  ? 209 LYS F CA  1 
ATOM   13033 C  C   . LYS F 1 209 ? 38.716  -11.843 42.071  1.00 27.85  ? 209 LYS F C   1 
ATOM   13034 O  O   . LYS F 1 209 ? 38.182  -10.804 41.672  1.00 24.34  ? 209 LYS F O   1 
ATOM   13035 C  CB  . LYS F 1 209 ? 41.166  -12.094 42.679  1.00 28.15  ? 209 LYS F CB  1 
ATOM   13036 C  CG  . LYS F 1 209 ? 41.635  -11.129 41.604  1.00 30.22  ? 209 LYS F CG  1 
ATOM   13037 C  CD  . LYS F 1 209 ? 43.112  -11.323 41.258  1.00 29.22  ? 209 LYS F CD  1 
ATOM   13038 C  CE  . LYS F 1 209 ? 43.612  -10.137 40.451  1.00 27.59  ? 209 LYS F CE  1 
ATOM   13039 N  NZ  . LYS F 1 209 ? 44.987  -10.379 40.083  1.00 26.36  ? 209 LYS F NZ  1 
ATOM   13040 N  N   . MET F 1 210 ? 38.384  -13.080 41.632  1.00 29.17  ? 210 MET F N   1 
ATOM   13041 C  CA  . MET F 1 210 ? 37.439  -13.292 40.517  1.00 29.47  ? 210 MET F CA  1 
ATOM   13042 C  C   . MET F 1 210 ? 36.017  -12.907 40.925  1.00 27.27  ? 210 MET F C   1 
ATOM   13043 O  O   . MET F 1 210 ? 35.462  -12.029 40.303  1.00 29.58  ? 210 MET F O   1 
ATOM   13044 C  CB  . MET F 1 210 ? 37.532  -14.662 39.796  1.00 35.54  ? 210 MET F CB  1 
ATOM   13045 C  CG  . MET F 1 210 ? 38.954  -14.985 39.173  1.00 42.15  ? 210 MET F CG  1 
ATOM   13046 S  SD  . MET F 1 210 ? 39.910  -13.787 38.135  1.00 54.62  ? 210 MET F SD  1 
ATOM   13047 C  CE  . MET F 1 210 ? 38.471  -13.736 37.023  1.00 72.04  ? 210 MET F CE  1 
ATOM   13048 N  N   . THR F 1 211 ? 35.504  -13.400 42.052  1.00 28.49  ? 211 THR F N   1 
ATOM   13049 C  CA  . THR F 1 211 ? 34.084  -13.277 42.432  1.00 28.81  ? 211 THR F CA  1 
ATOM   13050 C  C   . THR F 1 211 ? 33.810  -12.097 43.366  1.00 26.93  ? 211 THR F C   1 
ATOM   13051 O  O   . THR F 1 211 ? 32.663  -11.825 43.620  1.00 28.92  ? 211 THR F O   1 
ATOM   13052 C  CB  . THR F 1 211 ? 33.621  -14.568 43.120  1.00 30.04  ? 211 THR F CB  1 
ATOM   13053 O  OG1 . THR F 1 211 ? 34.406  -14.767 44.305  1.00 30.00  ? 211 THR F OG1 1 
ATOM   13054 C  CG2 . THR F 1 211 ? 33.855  -15.729 42.185  1.00 33.22  ? 211 THR F CG2 1 
ATOM   13055 N  N   . ASP F 1 212 ? 34.841  -11.458 43.957  1.00 26.20  ? 212 ASP F N   1 
ATOM   13056 C  CA  . ASP F 1 212 ? 34.683  -10.259 44.788  1.00 28.28  ? 212 ASP F CA  1 
ATOM   13057 C  C   . ASP F 1 212 ? 33.920  -10.566 46.070  1.00 30.61  ? 212 ASP F C   1 
ATOM   13058 O  O   . ASP F 1 212 ? 33.432  -9.670  46.725  1.00 28.69  ? 212 ASP F O   1 
ATOM   13059 C  CB  . ASP F 1 212 ? 33.995  -9.093  44.094  1.00 23.49  ? 212 ASP F CB  1 
ATOM   13060 C  CG  . ASP F 1 212 ? 34.161  -7.708  44.708  1.00 26.32  ? 212 ASP F CG  1 
ATOM   13061 O  OD1 . ASP F 1 212 ? 35.146  -7.441  45.486  1.00 27.62  ? 212 ASP F OD1 1 
ATOM   13062 O  OD2 . ASP F 1 212 ? 33.256  -6.897  44.386  1.00 30.40  ? 212 ASP F OD2 1 
ATOM   13063 N  N   . VAL F 1 213 ? 33.890  -11.828 46.490  1.00 37.28  ? 213 VAL F N   1 
ATOM   13064 C  CA  . VAL F 1 213 ? 33.279  -12.182 47.766  1.00 33.36  ? 213 VAL F CA  1 
ATOM   13065 C  C   . VAL F 1 213 ? 34.263  -11.929 48.915  1.00 31.16  ? 213 VAL F C   1 
ATOM   13066 O  O   . VAL F 1 213 ? 35.434  -12.305 48.848  1.00 29.97  ? 213 VAL F O   1 
ATOM   13067 C  CB  . VAL F 1 213 ? 32.830  -13.648 47.673  1.00 30.70  ? 213 VAL F CB  1 
ATOM   13068 C  CG1 . VAL F 1 213 ? 32.370  -14.139 49.007  1.00 31.20  ? 213 VAL F CG1 1 
ATOM   13069 C  CG2 . VAL F 1 213 ? 31.750  -13.834 46.605  1.00 29.82  ? 213 VAL F CG2 1 
ATOM   13070 N  N   . GLU F 1 214 ? 33.792  -11.293 49.997  1.00 30.57  ? 214 GLU F N   1 
ATOM   13071 C  CA  . GLU F 1 214 ? 34.673  -11.040 51.116  1.00 34.48  ? 214 GLU F CA  1 
ATOM   13072 C  C   . GLU F 1 214 ? 35.159  -12.357 51.748  1.00 39.05  ? 214 GLU F C   1 
ATOM   13073 O  O   . GLU F 1 214 ? 34.398  -13.316 51.830  1.00 30.09  ? 214 GLU F O   1 
ATOM   13074 C  CB  . GLU F 1 214 ? 33.869  -10.181 52.067  1.00 38.87  ? 214 GLU F CB  1 
ATOM   13075 C  CG  . GLU F 1 214 ? 34.628  -9.795  53.330  1.00 42.19  ? 214 GLU F CG  1 
ATOM   13076 C  CD  . GLU F 1 214 ? 33.975  -8.679  54.102  1.00 44.63  ? 214 GLU F CD  1 
ATOM   13077 O  OE1 . GLU F 1 214 ? 32.939  -8.155  53.661  1.00 52.70  ? 214 GLU F OE1 1 
ATOM   13078 O  OE2 . GLU F 1 214 ? 34.578  -8.236  55.089  1.00 53.90  ? 214 GLU F OE2 1 
ATOM   13079 N  N   . LEU F 1 215 ? 36.458  -12.415 52.123  1.00 40.22  ? 215 LEU F N   1 
ATOM   13080 C  CA  . LEU F 1 215 ? 37.027  -13.570 52.813  1.00 41.71  ? 215 LEU F CA  1 
ATOM   13081 C  C   . LEU F 1 215 ? 36.343  -13.659 54.163  1.00 44.06  ? 215 LEU F C   1 
ATOM   13082 O  O   . LEU F 1 215 ? 36.069  -12.614 54.772  1.00 41.68  ? 215 LEU F O   1 
ATOM   13083 C  CB  . LEU F 1 215 ? 38.519  -13.369 53.047  1.00 37.39  ? 215 LEU F CB  1 
ATOM   13084 C  CG  . LEU F 1 215 ? 39.424  -13.415 51.829  1.00 37.35  ? 215 LEU F CG  1 
ATOM   13085 C  CD1 . LEU F 1 215 ? 40.857  -13.290 52.295  1.00 38.06  ? 215 LEU F CD1 1 
ATOM   13086 C  CD2 . LEU F 1 215 ? 39.142  -14.682 51.063  1.00 38.78  ? 215 LEU F CD2 1 
ATOM   13087 N  N   . SER F 1 216 ? 36.130  -14.877 54.657  1.00 52.01  ? 216 SER F N   1 
ATOM   13088 C  CA  . SER F 1 216 ? 35.379  -14.986 55.912  1.00 57.17  ? 216 SER F CA  1 
ATOM   13089 C  C   . SER F 1 216 ? 36.251  -14.535 57.086  1.00 53.73  ? 216 SER F C   1 
ATOM   13090 O  O   . SER F 1 216 ? 37.486  -14.551 56.949  1.00 50.64  ? 216 SER F O   1 
ATOM   13091 C  CB  . SER F 1 216 ? 34.866  -16.371 56.115  1.00 54.66  ? 216 SER F CB  1 
ATOM   13092 O  OG  . SER F 1 216 ? 35.985  -17.212 56.314  1.00 63.19  ? 216 SER F OG  1 
ATOM   13093 N  N   . ASP F 1 217 ? 35.603  -14.154 58.212  1.00 59.95  ? 217 ASP F N   1 
ATOM   13094 C  CA  . ASP F 1 217 ? 36.314  -13.568 59.361  1.00 59.60  ? 217 ASP F CA  1 
ATOM   13095 C  C   . ASP F 1 217 ? 37.427  -14.491 59.893  1.00 51.07  ? 217 ASP F C   1 
ATOM   13096 O  O   . ASP F 1 217 ? 38.487  -14.015 60.254  1.00 42.96  ? 217 ASP F O   1 
ATOM   13097 C  CB  . ASP F 1 217 ? 35.362  -13.075 60.437  1.00 50.76  ? 217 ASP F CB  1 
ATOM   13098 C  CG  . ASP F 1 217 ? 34.291  -12.137 59.919  1.00 59.12  ? 217 ASP F CG  1 
ATOM   13099 O  OD1 . ASP F 1 217 ? 34.606  -11.252 59.104  1.00 58.28  ? 217 ASP F OD1 1 
ATOM   13100 O  OD2 . ASP F 1 217 ? 33.148  -12.338 60.307  1.00 68.94  ? 217 ASP F OD2 1 
ATOM   13101 N  N   . ASP F 1 218 ? 37.228  -15.816 59.897  1.00 60.05  ? 218 ASP F N   1 
ATOM   13102 C  CA  . ASP F 1 218 ? 38.260  -16.724 60.390  1.00 69.67  ? 218 ASP F CA  1 
ATOM   13103 C  C   . ASP F 1 218 ? 39.428  -16.800 59.388  1.00 62.02  ? 218 ASP F C   1 
ATOM   13104 O  O   . ASP F 1 218 ? 40.514  -17.159 59.798  1.00 46.99  ? 218 ASP F O   1 
ATOM   13105 C  CB  . ASP F 1 218 ? 37.662  -18.023 60.949  1.00 77.73  ? 218 ASP F CB  1 
ATOM   13106 C  CG  . ASP F 1 218 ? 37.066  -18.919 59.880  1.00 82.30  ? 218 ASP F CG  1 
ATOM   13107 O  OD1 . ASP F 1 218 ? 35.946  -18.629 59.464  1.00 86.22  ? 218 ASP F OD1 1 
ATOM   13108 O  OD2 . ASP F 1 218 ? 37.774  -19.812 59.383  1.00 81.87  ? 218 ASP F OD2 1 
ATOM   13109 N  N   . VAL F 1 219 ? 39.315  -16.374 58.109  1.00 64.23  ? 219 VAL F N   1 
ATOM   13110 C  CA  . VAL F 1 219 ? 40.500  -16.414 57.229  1.00 52.52  ? 219 VAL F CA  1 
ATOM   13111 C  C   . VAL F 1 219 ? 41.080  -15.030 56.868  1.00 43.22  ? 219 VAL F C   1 
ATOM   13112 O  O   . VAL F 1 219 ? 42.224  -14.928 56.450  1.00 37.16  ? 219 VAL F O   1 
ATOM   13113 C  CB  . VAL F 1 219 ? 40.197  -17.308 56.007  1.00 51.07  ? 219 VAL F CB  1 
ATOM   13114 C  CG1 . VAL F 1 219 ? 40.579  -16.737 54.653  1.00 47.78  ? 219 VAL F CG1 1 
ATOM   13115 C  CG2 . VAL F 1 219 ? 40.811  -18.688 56.184  1.00 48.38  ? 219 VAL F CG2 1 
ATOM   13116 N  N   . LYS F 1 220 ? 40.371  -13.943 57.120  1.00 43.03  ? 220 LYS F N   1 
ATOM   13117 C  CA  . LYS F 1 220 ? 40.832  -12.658 56.639  1.00 44.73  ? 220 LYS F CA  1 
ATOM   13118 C  C   . LYS F 1 220 ? 41.930  -12.119 57.539  1.00 38.17  ? 220 LYS F C   1 
ATOM   13119 O  O   . LYS F 1 220 ? 41.684  -11.794 58.681  1.00 34.58  ? 220 LYS F O   1 
ATOM   13120 C  CB  . LYS F 1 220 ? 39.646  -11.697 56.656  1.00 47.92  ? 220 LYS F CB  1 
ATOM   13121 C  CG  . LYS F 1 220 ? 39.947  -10.283 56.141  1.00 54.05  ? 220 LYS F CG  1 
ATOM   13122 C  CD  . LYS F 1 220 ? 38.862  -9.310  56.583  1.00 52.87  ? 220 LYS F CD  1 
ATOM   13123 C  CE  . LYS F 1 220 ? 37.578  -9.912  56.165  1.00 58.82  ? 220 LYS F CE  1 
ATOM   13124 N  NZ  . LYS F 1 220 ? 36.601  -8.877  56.423  1.00 59.94  ? 220 LYS F NZ  1 
ATOM   13125 N  N   . PRO F 1 221 ? 43.148  -11.893 57.019  1.00 36.28  ? 221 PRO F N   1 
ATOM   13126 C  CA  . PRO F 1 221 ? 44.219  -11.326 57.810  1.00 31.47  ? 221 PRO F CA  1 
ATOM   13127 C  C   . PRO F 1 221 ? 43.860  -9.964  58.375  1.00 30.50  ? 221 PRO F C   1 
ATOM   13128 O  O   . PRO F 1 221 ? 43.179  -9.186  57.754  1.00 30.84  ? 221 PRO F O   1 
ATOM   13129 C  CB  . PRO F 1 221 ? 45.399  -11.207 56.845  1.00 30.19  ? 221 PRO F CB  1 
ATOM   13130 C  CG  . PRO F 1 221 ? 45.083  -12.134 55.743  1.00 30.16  ? 221 PRO F CG  1 
ATOM   13131 C  CD  . PRO F 1 221 ? 43.563  -12.148 55.633  1.00 34.46  ? 221 PRO F CD  1 
ATOM   13132 N  N   . ALA F 1 222 ? 44.479  -9.677  59.512  1.00 30.73  ? 222 ALA F N   1 
ATOM   13133 C  CA  . ALA F 1 222 ? 44.372  -8.431  60.235  1.00 29.68  ? 222 ALA F CA  1 
ATOM   13134 C  C   . ALA F 1 222 ? 45.096  -7.294  59.507  1.00 30.98  ? 222 ALA F C   1 
ATOM   13135 O  O   . ALA F 1 222 ? 44.725  -6.137  59.711  1.00 43.25  ? 222 ALA F O   1 
ATOM   13136 C  CB  . ALA F 1 222 ? 45.000  -8.615  61.620  1.00 28.17  ? 222 ALA F CB  1 
ATOM   13137 N  N   . ASP F 1 223 ? 46.107  -7.591  58.673  1.00 29.75  ? 223 ASP F N   1 
ATOM   13138 C  CA  . ASP F 1 223 ? 46.797  -6.524  57.951  1.00 31.43  ? 223 ASP F CA  1 
ATOM   13139 C  C   . ASP F 1 223 ? 46.303  -6.448  56.498  1.00 31.79  ? 223 ASP F C   1 
ATOM   13140 O  O   . ASP F 1 223 ? 46.958  -5.788  55.676  1.00 30.78  ? 223 ASP F O   1 
ATOM   13141 C  CB  . ASP F 1 223 ? 48.303  -6.647  58.080  1.00 29.25  ? 223 ASP F CB  1 
ATOM   13142 C  CG  . ASP F 1 223 ? 48.848  -7.952  57.537  1.00 31.94  ? 223 ASP F CG  1 
ATOM   13143 O  OD1 . ASP F 1 223 ? 48.036  -8.851  57.272  1.00 32.73  ? 223 ASP F OD1 1 
ATOM   13144 O  OD2 . ASP F 1 223 ? 50.060  -8.015  57.281  1.00 39.25  ? 223 ASP F OD2 1 
ATOM   13145 N  N   . SER F 1 224 ? 45.147  -7.102  56.214  1.00 30.87  ? 224 SER F N   1 
ATOM   13146 C  CA  . SER F 1 224 ? 44.470  -6.925  54.938  1.00 31.39  ? 224 SER F CA  1 
ATOM   13147 C  C   . SER F 1 224 ? 43.814  -5.543  54.870  1.00 31.34  ? 224 SER F C   1 
ATOM   13148 O  O   . SER F 1 224 ? 43.442  -4.959  55.909  1.00 29.40  ? 224 SER F O   1 
ATOM   13149 C  CB  . SER F 1 224 ? 43.477  -8.009  54.641  1.00 30.80  ? 224 SER F CB  1 
ATOM   13150 O  OG  . SER F 1 224 ? 42.298  -7.835  55.394  1.00 29.26  ? 224 SER F OG  1 
ATOM   13151 N  N   . HIS F 1 225 ? 43.695  -5.034  53.630  1.00 26.21  ? 225 HIS F N   1 
ATOM   13152 C  CA  . HIS F 1 225 ? 43.227  -3.677  53.387  1.00 23.77  ? 225 HIS F CA  1 
ATOM   13153 C  C   . HIS F 1 225 ? 41.825  -3.487  53.930  1.00 24.12  ? 225 HIS F C   1 
ATOM   13154 O  O   . HIS F 1 225 ? 41.513  -2.478  54.561  1.00 24.82  ? 225 HIS F O   1 
ATOM   13155 C  CB  . HIS F 1 225 ? 43.355  -3.390  51.882  1.00 25.80  ? 225 HIS F CB  1 
ATOM   13156 C  CG  . HIS F 1 225 ? 42.859  -2.057  51.467  1.00 22.12  ? 225 HIS F CG  1 
ATOM   13157 N  ND1 . HIS F 1 225 ? 43.404  -0.911  51.975  1.00 23.98  ? 225 HIS F ND1 1 
ATOM   13158 C  CD2 . HIS F 1 225 ? 41.876  -1.686  50.652  1.00 25.05  ? 225 HIS F CD2 1 
ATOM   13159 C  CE1 . HIS F 1 225 ? 42.730  0.128   51.478  1.00 25.54  ? 225 HIS F CE1 1 
ATOM   13160 N  NE2 . HIS F 1 225 ? 41.793  -0.324  50.638  1.00 26.17  ? 225 HIS F NE2 1 
ATOM   13161 N  N   . VAL F 1 226 ? 40.975  -4.482  53.673  1.00 25.30  ? 226 VAL F N   1 
ATOM   13162 C  CA  . VAL F 1 226 ? 39.595  -4.431  54.113  1.00 31.37  ? 226 VAL F CA  1 
ATOM   13163 C  C   . VAL F 1 226 ? 39.525  -4.473  55.641  1.00 31.17  ? 226 VAL F C   1 
ATOM   13164 O  O   . VAL F 1 226 ? 38.665  -3.850  56.222  1.00 31.62  ? 226 VAL F O   1 
ATOM   13165 C  CB  . VAL F 1 226 ? 38.787  -5.565  53.468  1.00 29.71  ? 226 VAL F CB  1 
ATOM   13166 C  CG1 . VAL F 1 226 ? 37.525  -5.848  54.223  1.00 35.13  ? 226 VAL F CG1 1 
ATOM   13167 C  CG2 . VAL F 1 226 ? 38.427  -5.166  52.060  1.00 35.97  ? 226 VAL F CG2 1 
ATOM   13168 N  N   . ALA F 1 227 ? 40.394  -5.237  56.290  1.00 28.44  ? 227 ALA F N   1 
ATOM   13169 C  CA  . ALA F 1 227 ? 40.356  -5.335  57.738  1.00 26.11  ? 227 ALA F CA  1 
ATOM   13170 C  C   . ALA F 1 227 ? 40.720  -3.971  58.315  1.00 27.94  ? 227 ALA F C   1 
ATOM   13171 O  O   . ALA F 1 227 ? 40.001  -3.485  59.180  1.00 30.27  ? 227 ALA F O   1 
ATOM   13172 C  CB  . ALA F 1 227 ? 41.292  -6.415  58.272  1.00 25.55  ? 227 ALA F CB  1 
ATOM   13173 N  N   . LEU F 1 228 ? 41.821  -3.355  57.842  1.00 27.52  ? 228 LEU F N   1 
ATOM   13174 C  CA  . LEU F 1 228 ? 42.244  -2.057  58.359  1.00 29.07  ? 228 LEU F CA  1 
ATOM   13175 C  C   . LEU F 1 228 ? 41.300  -0.903  58.021  1.00 29.40  ? 228 LEU F C   1 
ATOM   13176 O  O   . LEU F 1 228 ? 41.220  0.039   58.806  1.00 33.97  ? 228 LEU F O   1 
ATOM   13177 C  CB  . LEU F 1 228 ? 43.674  -1.750  57.936  1.00 30.72  ? 228 LEU F CB  1 
ATOM   13178 C  CG  . LEU F 1 228 ? 44.738  -2.670  58.558  1.00 36.57  ? 228 LEU F CG  1 
ATOM   13179 C  CD1 . LEU F 1 228 ? 46.054  -2.526  57.829  1.00 40.39  ? 228 LEU F CD1 1 
ATOM   13180 C  CD2 . LEU F 1 228 ? 44.926  -2.351  60.026  1.00 35.09  ? 228 LEU F CD2 1 
ATOM   13181 N  N   . THR F 1 229 ? 40.609  -0.907  56.887  1.00 27.89  ? 229 THR F N   1 
ATOM   13182 C  CA  . THR F 1 229 ? 39.787  0.243   56.562  1.00 26.70  ? 229 THR F CA  1 
ATOM   13183 C  C   . THR F 1 229 ? 38.355  0.006   57.020  1.00 32.85  ? 229 THR F C   1 
ATOM   13184 O  O   . THR F 1 229 ? 37.511  0.831   56.673  1.00 38.86  ? 229 THR F O   1 
ATOM   13185 C  CB  . THR F 1 229 ? 39.827  0.501   55.064  1.00 30.25  ? 229 THR F CB  1 
ATOM   13186 O  OG1 . THR F 1 229 ? 39.475  -0.668  54.313  1.00 30.27  ? 229 THR F OG1 1 
ATOM   13187 C  CG2 . THR F 1 229 ? 41.207  0.936   54.616  1.00 38.67  ? 229 THR F CG2 1 
ATOM   13188 N  N   . SER F 1 230 ? 38.070  -1.100  57.757  1.00 32.80  ? 230 SER F N   1 
ATOM   13189 C  CA  . SER F 1 230 ? 36.800  -1.253  58.483  1.00 37.47  ? 230 SER F CA  1 
ATOM   13190 C  C   . SER F 1 230 ? 36.940  -0.676  59.884  1.00 41.48  ? 230 SER F C   1 
ATOM   13191 O  O   . SER F 1 230 ? 37.828  -1.057  60.606  1.00 46.14  ? 230 SER F O   1 
ATOM   13192 C  CB  . SER F 1 230 ? 36.344  -2.643  58.596  1.00 34.14  ? 230 SER F CB  1 
ATOM   13193 O  OG  . SER F 1 230 ? 36.221  -3.143  57.286  1.00 30.51  ? 230 SER F OG  1 
ATOM   13194 N  N   . VAL F 1 231 ? 36.158  0.357   60.185  1.00 45.75  ? 231 VAL F N   1 
ATOM   13195 C  CA  . VAL F 1 231 ? 36.254  1.109   61.420  1.00 52.06  ? 231 VAL F CA  1 
ATOM   13196 C  C   . VAL F 1 231 ? 34.848  1.161   62.003  1.00 50.51  ? 231 VAL F C   1 
ATOM   13197 O  O   . VAL F 1 231 ? 33.897  1.452   61.292  1.00 46.11  ? 231 VAL F O   1 
ATOM   13198 C  CB  . VAL F 1 231 ? 36.798  2.517   61.138  1.00 57.89  ? 231 VAL F CB  1 
ATOM   13199 C  CG1 . VAL F 1 231 ? 36.841  3.375   62.386  1.00 60.32  ? 231 VAL F CG1 1 
ATOM   13200 C  CG2 . VAL F 1 231 ? 38.167  2.385   60.494  1.00 65.25  ? 231 VAL F CG2 1 
ATOM   13201 N  N   . THR F 1 232 ? 34.712  0.853   63.290  1.00 65.01  ? 232 THR F N   1 
ATOM   13202 C  CA  . THR F 1 232 ? 33.467  1.093   64.003  1.00 64.45  ? 232 THR F CA  1 
ATOM   13203 C  C   . THR F 1 232 ? 33.690  2.331   64.875  1.00 64.63  ? 232 THR F C   1 
ATOM   13204 O  O   . THR F 1 232 ? 34.823  2.591   65.309  1.00 49.69  ? 232 THR F O   1 
ATOM   13205 C  CB  . THR F 1 232 ? 33.071  -0.181  64.754  1.00 63.77  ? 232 THR F CB  1 
ATOM   13206 O  OG1 . THR F 1 232 ? 34.376  -0.584  65.161  1.00 56.76  ? 232 THR F OG1 1 
ATOM   13207 C  CG2 . THR F 1 232 ? 32.496  -1.259  63.850  1.00 63.13  ? 232 THR F CG2 1 
ATOM   13208 N  N   . GLY F 1 233 ? 32.634  3.152   65.013  1.00 60.37  ? 233 GLY F N   1 
ATOM   13209 C  CA  . GLY F 1 233 ? 32.767  4.387   65.755  1.00 83.92  ? 233 GLY F CA  1 
ATOM   13210 C  C   . GLY F 1 233 ? 32.640  4.097   67.251  1.00 106.65 ? 233 GLY F C   1 
ATOM   13211 O  O   . GLY F 1 233 ? 32.188  3.009   67.645  1.00 65.42  ? 233 GLY F O   1 
ATOM   13212 N  N   . PRO F 1 234 ? 32.983  5.065   68.144  1.00 135.16 ? 234 PRO F N   1 
ATOM   13213 C  CA  . PRO F 1 234 ? 32.244  5.158   69.413  1.00 118.06 ? 234 PRO F CA  1 
ATOM   13214 C  C   . PRO F 1 234 ? 30.778  4.652   69.385  1.00 103.45 ? 234 PRO F C   1 
ATOM   13215 O  O   . PRO F 1 234 ? 30.461  3.811   70.224  1.00 67.29  ? 234 PRO F O   1 
ATOM   13216 C  CB  . PRO F 1 234 ? 32.460  6.686   69.683  1.00 107.11 ? 234 PRO F CB  1 
ATOM   13217 C  CG  . PRO F 1 234 ? 33.924  6.944   69.239  1.00 90.54  ? 234 PRO F CG  1 
ATOM   13218 C  CD  . PRO F 1 234 ? 34.071  6.069   67.999  1.00 106.83 ? 234 PRO F CD  1 
ATOM   13219 N  N   . ASP F 1 235 ? 29.970  5.052   68.353  1.00 111.94 ? 235 ASP F N   1 
ATOM   13220 C  CA  . ASP F 1 235 ? 28.591  4.662   67.999  1.00 91.80  ? 235 ASP F CA  1 
ATOM   13221 C  C   . ASP F 1 235 ? 28.172  3.180   68.177  1.00 83.16  ? 235 ASP F C   1 
ATOM   13222 O  O   . ASP F 1 235 ? 26.989  2.941   68.284  1.00 72.73  ? 235 ASP F O   1 
ATOM   13223 C  CB  . ASP F 1 235 ? 28.224  5.117   66.573  1.00 60.10  ? 235 ASP F CB  1 
ATOM   13224 N  N   . GLY F 1 236 ? 29.025  2.142   68.138  1.00 85.89  ? 236 GLY F N   1 
ATOM   13225 C  CA  . GLY F 1 236 ? 28.535  0.780   67.867  1.00 69.53  ? 236 GLY F CA  1 
ATOM   13226 C  C   . GLY F 1 236 ? 28.616  0.410   66.364  1.00 77.92  ? 236 GLY F C   1 
ATOM   13227 O  O   . GLY F 1 236 ? 28.926  -0.723  65.998  1.00 59.29  ? 236 GLY F O   1 
ATOM   13228 N  N   . SER F 1 237 ? 28.411  1.390   65.460  1.00 92.85  ? 237 SER F N   1 
ATOM   13229 C  CA  . SER F 1 237 ? 28.140  1.157   64.041  1.00 86.28  ? 237 SER F CA  1 
ATOM   13230 C  C   . SER F 1 237 ? 29.337  1.542   63.146  1.00 79.13  ? 237 SER F C   1 
ATOM   13231 O  O   . SER F 1 237 ? 30.300  2.176   63.587  1.00 57.27  ? 237 SER F O   1 
ATOM   13232 C  CB  . SER F 1 237 ? 26.875  1.917   63.671  1.00 77.16  ? 237 SER F CB  1 
ATOM   13233 O  OG  . SER F 1 237 ? 26.907  3.196   64.297  1.00 82.06  ? 237 SER F OG  1 
ATOM   13234 N  N   . ASP F 1 238 ? 29.263  1.117   61.881  1.00 64.83  ? 238 ASP F N   1 
ATOM   13235 C  CA  . ASP F 1 238 ? 30.284  1.322   60.866  1.00 58.43  ? 238 ASP F CA  1 
ATOM   13236 C  C   . ASP F 1 238 ? 30.489  2.796   60.493  1.00 41.81  ? 238 ASP F C   1 
ATOM   13237 O  O   . ASP F 1 238 ? 29.576  3.571   60.352  1.00 44.79  ? 238 ASP F O   1 
ATOM   13238 C  CB  . ASP F 1 238 ? 29.870  0.530   59.632  1.00 72.66  ? 238 ASP F CB  1 
ATOM   13239 C  CG  . ASP F 1 238 ? 29.817  -0.961  59.887  1.00 61.85  ? 238 ASP F CG  1 
ATOM   13240 O  OD1 . ASP F 1 238 ? 30.012  -1.313  61.036  1.00 61.21  ? 238 ASP F OD1 1 
ATOM   13241 O  OD2 . ASP F 1 238 ? 29.709  -1.720  58.929  1.00 64.50  ? 238 ASP F OD2 1 
ATOM   13242 N  N   . LEU F 1 239 ? 31.735  3.196   60.344  1.00 40.78  ? 239 LEU F N   1 
ATOM   13243 C  CA  . LEU F 1 239 ? 32.096  4.478   59.783  1.00 48.35  ? 239 LEU F CA  1 
ATOM   13244 C  C   . LEU F 1 239 ? 32.427  4.324   58.298  1.00 41.34  ? 239 LEU F C   1 
ATOM   13245 O  O   . LEU F 1 239 ? 33.328  3.570   57.926  1.00 39.49  ? 239 LEU F O   1 
ATOM   13246 C  CB  . LEU F 1 239 ? 33.303  4.980   60.575  1.00 46.42  ? 239 LEU F CB  1 
ATOM   13247 C  CG  . LEU F 1 239 ? 32.903  5.558   61.939  1.00 50.26  ? 239 LEU F CG  1 
ATOM   13248 C  CD1 . LEU F 1 239 ? 34.193  6.206   62.415  1.00 53.18  ? 239 LEU F CD1 1 
ATOM   13249 C  CD2 . LEU F 1 239 ? 31.694  6.537   61.954  1.00 42.25  ? 239 LEU F CD2 1 
ATOM   13250 N  N   . GLU F 1 240 ? 31.735  5.094   57.470  1.00 30.41  ? 240 GLU F N   1 
ATOM   13251 C  CA  . GLU F 1 240 ? 31.822  4.898   56.043  1.00 29.33  ? 240 GLU F CA  1 
ATOM   13252 C  C   . GLU F 1 240 ? 32.384  6.122   55.337  1.00 26.68  ? 240 GLU F C   1 
ATOM   13253 O  O   . GLU F 1 240 ? 32.110  7.259   55.722  1.00 25.18  ? 240 GLU F O   1 
ATOM   13254 C  CB  . GLU F 1 240 ? 30.390  4.603   55.601  1.00 32.29  ? 240 GLU F CB  1 
ATOM   13255 C  CG  . GLU F 1 240 ? 29.952  3.235   56.099  1.00 37.13  ? 240 GLU F CG  1 
ATOM   13256 C  CD  . GLU F 1 240 ? 29.184  2.476   55.056  1.00 44.94  ? 240 GLU F CD  1 
ATOM   13257 O  OE1 . GLU F 1 240 ? 27.979  2.677   55.263  1.00 36.57  ? 240 GLU F OE1 1 
ATOM   13258 O  OE2 . GLU F 1 240 ? 29.788  1.867   54.080  1.00 54.06  ? 240 GLU F OE2 1 
ATOM   13259 N  N   . ILE F 1 241 ? 33.054  5.859   54.206  1.00 29.86  ? 241 ILE F N   1 
ATOM   13260 C  CA  . ILE F 1 241 ? 33.405  6.901   53.240  1.00 29.41  ? 241 ILE F CA  1 
ATOM   13261 C  C   . ILE F 1 241 ? 32.904  6.468   51.857  1.00 27.43  ? 241 ILE F C   1 
ATOM   13262 O  O   . ILE F 1 241 ? 32.456  5.328   51.643  1.00 22.29  ? 241 ILE F O   1 
ATOM   13263 C  CB  . ILE F 1 241 ? 34.918  7.249   53.229  1.00 26.15  ? 241 ILE F CB  1 
ATOM   13264 C  CG1 . ILE F 1 241 ? 35.738  6.100   52.681  1.00 26.76  ? 241 ILE F CG1 1 
ATOM   13265 C  CG2 . ILE F 1 241 ? 35.396  7.665   54.629  1.00 26.14  ? 241 ILE F CG2 1 
ATOM   13266 C  CD1 . ILE F 1 241 ? 37.174  6.429   52.467  1.00 26.65  ? 241 ILE F CD1 1 
ATOM   13267 N  N   . LEU F 1 242 ? 32.970  7.448   50.942  1.00 26.28  ? 242 LEU F N   1 
ATOM   13268 C  CA  . LEU F 1 242 ? 32.506  7.273   49.594  1.00 23.66  ? 242 LEU F CA  1 
ATOM   13269 C  C   . LEU F 1 242 ? 33.728  7.491   48.734  1.00 22.03  ? 242 LEU F C   1 
ATOM   13270 O  O   . LEU F 1 242 ? 34.229  8.599   48.699  1.00 22.28  ? 242 LEU F O   1 
ATOM   13271 C  CB  . LEU F 1 242 ? 31.429  8.258   49.186  1.00 21.08  ? 242 LEU F CB  1 
ATOM   13272 C  CG  . LEU F 1 242 ? 30.880  8.045   47.775  1.00 23.75  ? 242 LEU F CG  1 
ATOM   13273 C  CD1 . LEU F 1 242 ? 30.087  6.786   47.710  1.00 25.37  ? 242 LEU F CD1 1 
ATOM   13274 C  CD2 . LEU F 1 242 ? 30.040  9.228   47.364  1.00 26.65  ? 242 LEU F CD2 1 
ATOM   13275 N  N   . ARG F 1 243 ? 34.115  6.447   48.018  1.00 18.93  ? 243 ARG F N   1 
ATOM   13276 C  CA  . ARG F 1 243 ? 35.303  6.446   47.218  1.00 21.69  ? 243 ARG F CA  1 
ATOM   13277 C  C   . ARG F 1 243 ? 34.939  6.399   45.749  1.00 26.47  ? 243 ARG F C   1 
ATOM   13278 O  O   . ARG F 1 243 ? 33.889  5.853   45.413  1.00 24.67  ? 243 ARG F O   1 
ATOM   13279 C  CB  . ARG F 1 243 ? 36.153  5.210   47.489  1.00 22.41  ? 243 ARG F CB  1 
ATOM   13280 C  CG  . ARG F 1 243 ? 36.733  5.226   48.898  1.00 22.57  ? 243 ARG F CG  1 
ATOM   13281 C  CD  . ARG F 1 243 ? 37.230  3.863   49.265  1.00 26.66  ? 243 ARG F CD  1 
ATOM   13282 N  NE  . ARG F 1 243 ? 36.106  2.903   49.446  1.00 30.75  ? 243 ARG F NE  1 
ATOM   13283 C  CZ  . ARG F 1 243 ? 35.978  1.739   48.667  1.00 29.14  ? 243 ARG F CZ  1 
ATOM   13284 N  NH1 . ARG F 1 243 ? 36.949  1.329   47.819  1.00 30.38  ? 243 ARG F NH1 1 
ATOM   13285 N  NH2 . ARG F 1 243 ? 34.908  0.975   48.776  1.00 28.06  ? 243 ARG F NH2 1 
ATOM   13286 N  N   . ASP F 1 244 ? 35.798  7.016   44.910  1.00 25.70  ? 244 ASP F N   1 
ATOM   13287 C  CA  . ASP F 1 244 ? 35.665  6.892   43.481  1.00 24.50  ? 244 ASP F CA  1 
ATOM   13288 C  C   . ASP F 1 244 ? 37.062  6.760   42.850  1.00 24.08  ? 244 ASP F C   1 
ATOM   13289 O  O   . ASP F 1 244 ? 37.483  7.593   42.036  1.00 21.02  ? 244 ASP F O   1 
ATOM   13290 C  CB  . ASP F 1 244 ? 34.745  7.996   42.958  1.00 23.49  ? 244 ASP F CB  1 
ATOM   13291 C  CG  . ASP F 1 244 ? 34.109  7.650   41.612  1.00 24.80  ? 244 ASP F CG  1 
ATOM   13292 O  OD1 . ASP F 1 244 ? 34.289  6.498   41.094  1.00 24.66  ? 244 ASP F OD1 1 
ATOM   13293 O  OD2 . ASP F 1 244 ? 33.596  8.547   40.968  1.00 28.65  ? 244 ASP F OD2 1 
ATOM   13294 N  N   . ASN F 1 245 ? 37.779  5.711   43.237  1.00 24.45  ? 245 ASN F N   1 
ATOM   13295 C  CA  . ASN F 1 245 ? 39.147  5.507   42.782  1.00 24.68  ? 245 ASN F CA  1 
ATOM   13296 C  C   . ASN F 1 245 ? 39.171  5.260   41.272  1.00 23.12  ? 245 ASN F C   1 
ATOM   13297 O  O   . ASN F 1 245 ? 38.341  4.555   40.741  1.00 24.06  ? 245 ASN F O   1 
ATOM   13298 C  CB  . ASN F 1 245 ? 39.779  4.305   43.464  1.00 24.10  ? 245 ASN F CB  1 
ATOM   13299 C  CG  . ASN F 1 245 ? 39.792  4.450   44.965  1.00 27.68  ? 245 ASN F CG  1 
ATOM   13300 O  OD1 . ASN F 1 245 ? 39.608  5.555   45.506  1.00 27.76  ? 245 ASN F OD1 1 
ATOM   13301 N  ND2 . ASN F 1 245 ? 40.015  3.329   45.635  1.00 34.08  ? 245 ASN F ND2 1 
ATOM   13302 N  N   . MET F 1 246 ? 40.163  5.811   40.601  1.00 23.05  ? 246 MET F N   1 
ATOM   13303 C  CA  . MET F 1 246 ? 40.297  5.696   39.161  1.00 24.15  ? 246 MET F CA  1 
ATOM   13304 C  C   . MET F 1 246 ? 41.705  5.224   38.853  1.00 20.44  ? 246 MET F C   1 
ATOM   13305 O  O   . MET F 1 246 ? 42.662  5.873   39.219  1.00 23.01  ? 246 MET F O   1 
ATOM   13306 C  CB  . MET F 1 246 ? 40.054  7.019   38.409  1.00 25.47  ? 246 MET F CB  1 
ATOM   13307 C  CG  . MET F 1 246 ? 38.632  7.494   38.440  1.00 28.89  ? 246 MET F CG  1 
ATOM   13308 S  SD  . MET F 1 246 ? 37.442  6.358   37.686  1.00 29.66  ? 246 MET F SD  1 
ATOM   13309 C  CE  . MET F 1 246 ? 37.718  6.877   36.012  1.00 34.44  ? 246 MET F CE  1 
ATOM   13310 N  N   . PRO F 1 247 ? 41.835  4.181   38.035  1.00 17.84  ? 247 PRO F N   1 
ATOM   13311 C  CA  . PRO F 1 247 ? 43.100  3.858   37.422  1.00 20.51  ? 247 PRO F CA  1 
ATOM   13312 C  C   . PRO F 1 247 ? 43.591  4.980   36.503  1.00 25.63  ? 247 PRO F C   1 
ATOM   13313 O  O   . PRO F 1 247 ? 42.803  5.710   35.865  1.00 24.81  ? 247 PRO F O   1 
ATOM   13314 C  CB  . PRO F 1 247 ? 42.752  2.631   36.595  1.00 20.54  ? 247 PRO F CB  1 
ATOM   13315 C  CG  . PRO F 1 247 ? 41.458  2.113   37.145  1.00 20.19  ? 247 PRO F CG  1 
ATOM   13316 C  CD  . PRO F 1 247 ? 40.736  3.323   37.583  1.00 18.76  ? 247 PRO F CD  1 
ATOM   13317 N  N   . PHE F 1 248 ? 44.912  5.062   36.365  1.00 26.58  ? 248 PHE F N   1 
ATOM   13318 C  CA  . PHE F 1 248 ? 45.526  5.938   35.371  1.00 25.57  ? 248 PHE F CA  1 
ATOM   13319 C  C   . PHE F 1 248 ? 46.884  5.373   35.050  1.00 26.46  ? 248 PHE F C   1 
ATOM   13320 O  O   . PHE F 1 248 ? 47.378  4.489   35.756  1.00 27.79  ? 248 PHE F O   1 
ATOM   13321 C  CB  . PHE F 1 248 ? 45.657  7.365   35.872  1.00 23.71  ? 248 PHE F CB  1 
ATOM   13322 C  CG  . PHE F 1 248 ? 46.664  7.486   36.989  1.00 25.93  ? 248 PHE F CG  1 
ATOM   13323 C  CD1 . PHE F 1 248 ? 47.990  7.700   36.701  1.00 23.57  ? 248 PHE F CD1 1 
ATOM   13324 C  CD2 . PHE F 1 248 ? 46.288  7.318   38.306  1.00 25.46  ? 248 PHE F CD2 1 
ATOM   13325 C  CE1 . PHE F 1 248 ? 48.922  7.767   37.712  1.00 24.89  ? 248 PHE F CE1 1 
ATOM   13326 C  CE2 . PHE F 1 248 ? 47.234  7.439   39.300  1.00 27.62  ? 248 PHE F CE2 1 
ATOM   13327 C  CZ  . PHE F 1 248 ? 48.532  7.712   38.995  1.00 24.71  ? 248 PHE F CZ  1 
ATOM   13328 N  N   . GLY F 1 249 ? 47.494  5.849   33.978  1.00 28.35  ? 249 GLY F N   1 
ATOM   13329 C  CA  . GLY F 1 249 ? 48.869  5.443   33.799  1.00 28.17  ? 249 GLY F CA  1 
ATOM   13330 C  C   . GLY F 1 249 ? 49.405  5.746   32.418  1.00 27.97  ? 249 GLY F C   1 
ATOM   13331 O  O   . GLY F 1 249 ? 48.716  6.314   31.564  1.00 26.61  ? 249 GLY F O   1 
ATOM   13332 N  N   . SER F 1 250 ? 50.630  5.254   32.224  1.00 31.03  ? 250 SER F N   1 
ATOM   13333 C  CA  . SER F 1 250 ? 51.368  5.462   31.001  1.00 29.87  ? 250 SER F CA  1 
ATOM   13334 C  C   . SER F 1 250 ? 52.255  4.249   30.778  1.00 28.66  ? 250 SER F C   1 
ATOM   13335 O  O   . SER F 1 250 ? 53.081  3.915   31.640  1.00 27.97  ? 250 SER F O   1 
ATOM   13336 C  CB  . SER F 1 250 ? 52.158  6.729   31.125  1.00 31.58  ? 250 SER F CB  1 
ATOM   13337 O  OG  . SER F 1 250 ? 53.290  6.629   30.260  1.00 41.83  ? 250 SER F OG  1 
ATOM   13338 N  N   . VAL F 1 251 ? 52.053  3.538   29.683  1.00 25.64  ? 251 VAL F N   1 
ATOM   13339 C  CA  . VAL F 1 251 ? 52.684  2.255   29.562  1.00 26.62  ? 251 VAL F CA  1 
ATOM   13340 C  C   . VAL F 1 251 ? 54.153  2.401   29.183  1.00 32.83  ? 251 VAL F C   1 
ATOM   13341 O  O   . VAL F 1 251 ? 54.990  1.598   29.583  1.00 33.00  ? 251 VAL F O   1 
ATOM   13342 C  CB  . VAL F 1 251 ? 51.825  1.562   28.528  1.00 34.39  ? 251 VAL F CB  1 
ATOM   13343 C  CG1 . VAL F 1 251 ? 52.563  1.427   27.231  1.00 40.64  ? 251 VAL F CG1 1 
ATOM   13344 C  CG2 . VAL F 1 251 ? 51.390  0.219   29.042  1.00 42.63  ? 251 VAL F CG2 1 
ATOM   13345 N  N   . GLY F 1 252 ? 54.494  3.439   28.428  1.00 34.82  ? 252 GLY F N   1 
ATOM   13346 C  CA  . GLY F 1 252 ? 55.879  3.719   28.114  1.00 35.83  ? 252 GLY F CA  1 
ATOM   13347 C  C   . GLY F 1 252 ? 56.691  4.014   29.367  1.00 33.70  ? 252 GLY F C   1 
ATOM   13348 O  O   . GLY F 1 252 ? 57.811  3.544   29.501  1.00 38.30  ? 252 GLY F O   1 
ATOM   13349 N  N   . ARG F 1 253 ? 56.173  4.820   30.283  1.00 31.99  ? 253 ARG F N   1 
ATOM   13350 C  CA  . ARG F 1 253 ? 56.907  5.176   31.492  1.00 33.37  ? 253 ARG F CA  1 
ATOM   13351 C  C   . ARG F 1 253 ? 56.792  4.113   32.583  1.00 34.71  ? 253 ARG F C   1 
ATOM   13352 O  O   . ARG F 1 253 ? 57.253  4.303   33.687  1.00 45.61  ? 253 ARG F O   1 
ATOM   13353 C  CB  . ARG F 1 253 ? 56.360  6.492   32.039  1.00 35.37  ? 253 ARG F CB  1 
ATOM   13354 C  CG  . ARG F 1 253 ? 56.777  7.628   31.127  1.00 49.45  ? 253 ARG F CG  1 
ATOM   13355 C  CD  . ARG F 1 253 ? 57.019  8.953   31.881  1.00 63.65  ? 253 ARG F CD  1 
ATOM   13356 N  NE  . ARG F 1 253 ? 55.747  9.346   32.474  1.00 73.10  ? 253 ARG F NE  1 
ATOM   13357 C  CZ  . ARG F 1 253 ? 54.674  9.630   31.735  1.00 82.38  ? 253 ARG F CZ  1 
ATOM   13358 N  NH1 . ARG F 1 253 ? 54.729  9.649   30.407  1.00 76.57  ? 253 ARG F NH1 1 
ATOM   13359 N  NH2 . ARG F 1 253 ? 53.529  9.896   32.347  1.00 85.29  ? 253 ARG F NH2 1 
ATOM   13360 N  N   . GLU F 1 254 ? 56.136  2.985   32.316  1.00 36.16  ? 254 GLU F N   1 
ATOM   13361 C  CA  . GLU F 1 254 ? 55.810  1.998   33.341  1.00 36.05  ? 254 GLU F CA  1 
ATOM   13362 C  C   . GLU F 1 254 ? 55.114  2.618   34.563  1.00 31.65  ? 254 GLU F C   1 
ATOM   13363 O  O   . GLU F 1 254 ? 55.366  2.179   35.639  1.00 35.08  ? 254 GLU F O   1 
ATOM   13364 C  CB  . GLU F 1 254 ? 57.123  1.317   33.700  1.00 44.40  ? 254 GLU F CB  1 
ATOM   13365 C  CG  . GLU F 1 254 ? 57.052  -0.209  33.680  1.00 62.57  ? 254 GLU F CG  1 
ATOM   13366 C  CD  . GLU F 1 254 ? 58.386  -0.895  33.968  1.00 70.21  ? 254 GLU F CD  1 
ATOM   13367 O  OE1 . GLU F 1 254 ? 59.410  -0.494  33.353  1.00 63.36  ? 254 GLU F OE1 1 
ATOM   13368 O  OE2 . GLU F 1 254 ? 58.380  -1.849  34.793  1.00 73.06  ? 254 GLU F OE2 1 
ATOM   13369 N  N   . GLU F 1 255 ? 54.179  3.559   34.437  1.00 25.44  ? 255 GLU F N   1 
ATOM   13370 C  CA  . GLU F 1 255 ? 53.429  4.077   35.549  1.00 25.19  ? 255 GLU F CA  1 
ATOM   13371 C  C   . GLU F 1 255 ? 52.043  3.447   35.536  1.00 31.16  ? 255 GLU F C   1 
ATOM   13372 O  O   . GLU F 1 255 ? 51.310  3.548   34.542  1.00 27.70  ? 255 GLU F O   1 
ATOM   13373 C  CB  . GLU F 1 255 ? 53.121  5.555   35.427  1.00 27.53  ? 255 GLU F CB  1 
ATOM   13374 C  CG  . GLU F 1 255 ? 54.351  6.420   35.540  1.00 38.87  ? 255 GLU F CG  1 
ATOM   13375 C  CD  . GLU F 1 255 ? 53.827  7.844   35.472  1.00 52.02  ? 255 GLU F CD  1 
ATOM   13376 O  OE1 . GLU F 1 255 ? 52.582  8.144   35.585  1.00 52.11  ? 255 GLU F OE1 1 
ATOM   13377 O  OE2 . GLU F 1 255 ? 54.764  8.647   35.284  1.00 59.87  ? 255 GLU F OE2 1 
ATOM   13378 N  N   . PHE F 1 256 ? 51.718  2.729   36.631  1.00 28.48  ? 256 PHE F N   1 
ATOM   13379 C  CA  . PHE F 1 256 ? 50.403  2.158   36.730  1.00 29.82  ? 256 PHE F CA  1 
ATOM   13380 C  C   . PHE F 1 256 ? 49.856  2.615   38.047  1.00 26.99  ? 256 PHE F C   1 
ATOM   13381 O  O   . PHE F 1 256 ? 50.461  2.255   39.010  1.00 29.40  ? 256 PHE F O   1 
ATOM   13382 C  CB  . PHE F 1 256 ? 50.511  0.645   36.711  1.00 35.33  ? 256 PHE F CB  1 
ATOM   13383 C  CG  . PHE F 1 256 ? 51.138  0.130   35.440  1.00 38.14  ? 256 PHE F CG  1 
ATOM   13384 C  CD1 . PHE F 1 256 ? 50.389  -0.072  34.305  1.00 45.82  ? 256 PHE F CD1 1 
ATOM   13385 C  CD2 . PHE F 1 256 ? 52.488  -0.118  35.386  1.00 40.94  ? 256 PHE F CD2 1 
ATOM   13386 C  CE1 . PHE F 1 256 ? 50.980  -0.564  33.151  1.00 46.52  ? 256 PHE F CE1 1 
ATOM   13387 C  CE2 . PHE F 1 256 ? 53.071  -0.641  34.241  1.00 42.84  ? 256 PHE F CE2 1 
ATOM   13388 C  CZ  . PHE F 1 256 ? 52.315  -0.870  33.137  1.00 44.83  ? 256 PHE F CZ  1 
ATOM   13389 N  N   . GLY F 1 257 ? 48.743  3.339   38.072  1.00 24.84  ? 257 GLY F N   1 
ATOM   13390 C  CA  . GLY F 1 257 ? 48.357  4.091   39.246  1.00 24.91  ? 257 GLY F CA  1 
ATOM   13391 C  C   . GLY F 1 257 ? 46.888  3.867   39.633  1.00 24.74  ? 257 GLY F C   1 
ATOM   13392 O  O   . GLY F 1 257 ? 46.066  3.303   38.863  1.00 25.00  ? 257 GLY F O   1 
ATOM   13393 N  N   . THR F 1 258 ? 46.601  4.276   40.867  1.00 20.06  ? 258 THR F N   1 
ATOM   13394 C  CA  . THR F 1 258 ? 45.267  4.438   41.379  1.00 18.77  ? 258 THR F CA  1 
ATOM   13395 C  C   . THR F 1 258 ? 45.180  5.839   41.948  1.00 19.23  ? 258 THR F C   1 
ATOM   13396 O  O   . THR F 1 258 ? 45.988  6.223   42.765  1.00 20.86  ? 258 THR F O   1 
ATOM   13397 C  CB  . THR F 1 258 ? 45.031  3.423   42.494  1.00 22.24  ? 258 THR F CB  1 
ATOM   13398 O  OG1 . THR F 1 258 ? 45.068  2.095   41.973  1.00 20.61  ? 258 THR F OG1 1 
ATOM   13399 C  CG2 . THR F 1 258 ? 43.723  3.737   43.205  1.00 25.35  ? 258 THR F CG2 1 
ATOM   13400 N  N   . TYR F 1 259 ? 44.225  6.620   41.507  1.00 17.90  ? 259 TYR F N   1 
ATOM   13401 C  CA  . TYR F 1 259 ? 43.955  7.927   42.040  1.00 18.10  ? 259 TYR F CA  1 
ATOM   13402 C  C   . TYR F 1 259 ? 42.858  7.731   43.057  1.00 18.39  ? 259 TYR F C   1 
ATOM   13403 O  O   . TYR F 1 259 ? 41.724  7.421   42.716  1.00 20.02  ? 259 TYR F O   1 
ATOM   13404 C  CB  . TYR F 1 259 ? 43.548  8.987   40.982  1.00 20.40  ? 259 TYR F CB  1 
ATOM   13405 C  CG  . TYR F 1 259 ? 43.781  10.411  41.451  1.00 20.99  ? 259 TYR F CG  1 
ATOM   13406 C  CD1 . TYR F 1 259 ? 42.837  11.039  42.234  1.00 21.33  ? 259 TYR F CD1 1 
ATOM   13407 C  CD2 . TYR F 1 259 ? 44.957  11.104  41.179  1.00 23.42  ? 259 TYR F CD2 1 
ATOM   13408 C  CE1 . TYR F 1 259 ? 43.044  12.322  42.721  1.00 23.97  ? 259 TYR F CE1 1 
ATOM   13409 C  CE2 . TYR F 1 259 ? 45.173  12.381  41.658  1.00 23.11  ? 259 TYR F CE2 1 
ATOM   13410 C  CZ  . TYR F 1 259 ? 44.219  13.011  42.438  1.00 27.86  ? 259 TYR F CZ  1 
ATOM   13411 O  OH  . TYR F 1 259 ? 44.456  14.292  42.910  1.00 26.26  ? 259 TYR F OH  1 
ATOM   13412 N  N   . PHE F 1 260 ? 43.230  7.860   44.325  1.00 19.42  ? 260 PHE F N   1 
ATOM   13413 C  CA  . PHE F 1 260 ? 42.307  7.714   45.426  1.00 23.78  ? 260 PHE F CA  1 
ATOM   13414 C  C   . PHE F 1 260 ? 41.618  9.046   45.676  1.00 24.14  ? 260 PHE F C   1 
ATOM   13415 O  O   . PHE F 1 260 ? 42.284  10.064  45.853  1.00 22.40  ? 260 PHE F O   1 
ATOM   13416 C  CB  . PHE F 1 260 ? 43.061  7.306   46.706  1.00 24.09  ? 260 PHE F CB  1 
ATOM   13417 C  CG  . PHE F 1 260 ? 42.166  7.319   47.928  1.00 24.35  ? 260 PHE F CG  1 
ATOM   13418 C  CD1 . PHE F 1 260 ? 41.278  6.276   48.156  1.00 25.22  ? 260 PHE F CD1 1 
ATOM   13419 C  CD2 . PHE F 1 260 ? 42.160  8.399   48.785  1.00 24.38  ? 260 PHE F CD2 1 
ATOM   13420 C  CE1 . PHE F 1 260 ? 40.430  6.300   49.242  1.00 25.46  ? 260 PHE F CE1 1 
ATOM   13421 C  CE2 . PHE F 1 260 ? 41.278  8.428   49.860  1.00 25.37  ? 260 PHE F CE2 1 
ATOM   13422 C  CZ  . PHE F 1 260 ? 40.409  7.407   50.075  1.00 23.67  ? 260 PHE F CZ  1 
ATOM   13423 N  N   . ILE F 1 261 ? 40.288  9.004   45.768  1.00 25.56  ? 261 ILE F N   1 
ATOM   13424 C  CA  . ILE F 1 261 ? 39.543  10.125  46.302  1.00 24.05  ? 261 ILE F CA  1 
ATOM   13425 C  C   . ILE F 1 261 ? 38.462  9.536   47.193  1.00 22.82  ? 261 ILE F C   1 
ATOM   13426 O  O   . ILE F 1 261 ? 37.762  8.603   46.804  1.00 26.57  ? 261 ILE F O   1 
ATOM   13427 C  CB  . ILE F 1 261 ? 38.986  11.074  45.217  1.00 24.09  ? 261 ILE F CB  1 
ATOM   13428 C  CG1 . ILE F 1 261 ? 38.285  12.288  45.841  1.00 26.34  ? 261 ILE F CG1 1 
ATOM   13429 C  CG2 . ILE F 1 261 ? 38.015  10.345  44.282  1.00 24.25  ? 261 ILE F CG2 1 
ATOM   13430 C  CD1 . ILE F 1 261 ? 38.057  13.410  44.829  1.00 27.95  ? 261 ILE F CD1 1 
ATOM   13431 N  N   . GLY F 1 262 ? 38.363  10.101  48.393  1.00 23.17  ? 262 GLY F N   1 
ATOM   13432 C  CA  . GLY F 1 262 ? 37.380  9.723   49.381  1.00 22.80  ? 262 GLY F CA  1 
ATOM   13433 C  C   . GLY F 1 262 ? 36.641  10.937  49.915  1.00 21.21  ? 262 GLY F C   1 
ATOM   13434 O  O   . GLY F 1 262 ? 37.257  11.877  50.386  1.00 22.89  ? 262 GLY F O   1 
ATOM   13435 N  N   . TYR F 1 263 ? 35.312  10.859  49.909  1.00 19.16  ? 263 TYR F N   1 
ATOM   13436 C  CA  . TYR F 1 263 ? 34.486  11.897  50.478  1.00 20.82  ? 263 TYR F CA  1 
ATOM   13437 C  C   . TYR F 1 263 ? 33.910  11.408  51.813  1.00 23.81  ? 263 TYR F C   1 
ATOM   13438 O  O   . TYR F 1 263 ? 33.548  10.228  51.925  1.00 24.42  ? 263 TYR F O   1 
ATOM   13439 C  CB  . TYR F 1 263 ? 33.348  12.209  49.524  1.00 20.09  ? 263 TYR F CB  1 
ATOM   13440 C  CG  . TYR F 1 263 ? 33.745  12.908  48.234  1.00 21.21  ? 263 TYR F CG  1 
ATOM   13441 C  CD1 . TYR F 1 263 ? 33.750  14.285  48.174  1.00 21.28  ? 263 TYR F CD1 1 
ATOM   13442 C  CD2 . TYR F 1 263 ? 34.010  12.203  47.067  1.00 22.01  ? 263 TYR F CD2 1 
ATOM   13443 C  CE1 . TYR F 1 263 ? 34.054  14.950  47.011  1.00 22.51  ? 263 TYR F CE1 1 
ATOM   13444 C  CE2 . TYR F 1 263 ? 34.344  12.870  45.897  1.00 22.71  ? 263 TYR F CE2 1 
ATOM   13445 C  CZ  . TYR F 1 263 ? 34.377  14.251  45.878  1.00 20.87  ? 263 TYR F CZ  1 
ATOM   13446 O  OH  . TYR F 1 263 ? 34.655  14.991  44.770  1.00 24.23  ? 263 TYR F OH  1 
ATOM   13447 N  N   . ALA F 1 264 ? 33.877  12.311  52.808  1.00 25.95  ? 264 ALA F N   1 
ATOM   13448 C  CA  . ALA F 1 264 ? 33.223  12.088  54.103  1.00 25.54  ? 264 ALA F CA  1 
ATOM   13449 C  C   . ALA F 1 264 ? 32.671  13.403  54.700  1.00 27.43  ? 264 ALA F C   1 
ATOM   13450 O  O   . ALA F 1 264 ? 33.134  14.504  54.353  1.00 27.42  ? 264 ALA F O   1 
ATOM   13451 C  CB  . ALA F 1 264 ? 34.188  11.374  55.008  1.00 23.66  ? 264 ALA F CB  1 
ATOM   13452 N  N   . ARG F 1 265 ? 31.689  13.293  55.609  1.00 24.51  ? 265 ARG F N   1 
ATOM   13453 C  CA  . ARG F 1 265 ? 31.060  14.447  56.239  1.00 29.27  ? 265 ARG F CA  1 
ATOM   13454 C  C   . ARG F 1 265 ? 32.007  15.097  57.244  1.00 28.90  ? 265 ARG F C   1 
ATOM   13455 O  O   . ARG F 1 265 ? 31.814  16.274  57.553  1.00 30.45  ? 265 ARG F O   1 
ATOM   13456 C  CB  . ARG F 1 265 ? 29.722  14.164  56.942  1.00 36.93  ? 265 ARG F CB  1 
ATOM   13457 C  CG  . ARG F 1 265 ? 29.790  13.442  58.279  1.00 51.56  ? 265 ARG F CG  1 
ATOM   13458 C  CD  . ARG F 1 265 ? 28.409  13.063  58.859  1.00 56.08  ? 265 ARG F CD  1 
ATOM   13459 N  NE  . ARG F 1 265 ? 27.521  14.230  58.961  1.00 51.15  ? 265 ARG F NE  1 
ATOM   13460 C  CZ  . ARG F 1 265 ? 26.197  14.216  59.162  1.00 55.31  ? 265 ARG F CZ  1 
ATOM   13461 N  NH1 . ARG F 1 265 ? 25.441  13.147  58.961  1.00 54.18  ? 265 ARG F NH1 1 
ATOM   13462 N  NH2 . ARG F 1 265 ? 25.578  15.330  59.481  1.00 47.26  ? 265 ARG F NH2 1 
ATOM   13463 N  N   . THR F 1 266 ? 33.043  14.367  57.693  1.00 28.10  ? 266 THR F N   1 
ATOM   13464 C  CA  . THR F 1 266 ? 34.132  14.972  58.460  1.00 32.15  ? 266 THR F CA  1 
ATOM   13465 C  C   . THR F 1 266 ? 35.435  14.256  58.074  1.00 31.99  ? 266 THR F C   1 
ATOM   13466 O  O   . THR F 1 266 ? 35.425  13.042  57.880  1.00 31.64  ? 266 THR F O   1 
ATOM   13467 C  CB  . THR F 1 266 ? 33.867  14.830  59.976  1.00 34.50  ? 266 THR F CB  1 
ATOM   13468 O  OG1 . THR F 1 266 ? 35.083  15.092  60.681  1.00 33.43  ? 266 THR F OG1 1 
ATOM   13469 C  CG2 . THR F 1 266 ? 33.558  13.383  60.376  1.00 35.12  ? 266 THR F CG2 1 
ATOM   13470 N  N   . PRO F 1 267 ? 36.609  14.927  58.051  1.00 27.11  ? 267 PRO F N   1 
ATOM   13471 C  CA  . PRO F 1 267 ? 37.850  14.261  57.743  1.00 26.85  ? 267 PRO F CA  1 
ATOM   13472 C  C   . PRO F 1 267 ? 38.326  13.267  58.784  1.00 31.79  ? 267 PRO F C   1 
ATOM   13473 O  O   . PRO F 1 267 ? 39.213  12.460  58.463  1.00 30.64  ? 267 PRO F O   1 
ATOM   13474 C  CB  . PRO F 1 267 ? 38.872  15.328  57.520  1.00 28.77  ? 267 PRO F CB  1 
ATOM   13475 C  CG  . PRO F 1 267 ? 38.242  16.561  57.981  1.00 29.22  ? 267 PRO F CG  1 
ATOM   13476 C  CD  . PRO F 1 267 ? 36.762  16.365  58.196  1.00 29.40  ? 267 PRO F CD  1 
ATOM   13477 N  N   . GLU F 1 268 ? 37.738  13.315  60.004  1.00 34.15  ? 268 GLU F N   1 
ATOM   13478 C  CA  . GLU F 1 268 ? 38.138  12.413  61.088  1.00 35.53  ? 268 GLU F CA  1 
ATOM   13479 C  C   . GLU F 1 268 ? 38.010  10.967  60.609  1.00 28.85  ? 268 GLU F C   1 
ATOM   13480 O  O   . GLU F 1 268 ? 38.870  10.118  60.883  1.00 26.35  ? 268 GLU F O   1 
ATOM   13481 C  CB  . GLU F 1 268 ? 37.351  12.701  62.366  1.00 49.06  ? 268 GLU F CB  1 
ATOM   13482 C  CG  . GLU F 1 268 ? 37.721  13.990  63.115  1.00 63.22  ? 268 GLU F CG  1 
ATOM   13483 C  CD  . GLU F 1 268 ? 37.093  13.584  64.426  1.00 83.20  ? 268 GLU F CD  1 
ATOM   13484 O  OE1 . GLU F 1 268 ? 35.845  13.693  64.605  1.00 74.28  ? 268 GLU F OE1 1 
ATOM   13485 O  OE2 . GLU F 1 268 ? 37.860  12.924  65.162  1.00 95.11  ? 268 GLU F OE2 1 
ATOM   13486 N  N   . VAL F 1 269 ? 36.965  10.680  59.821  1.00 26.28  ? 269 VAL F N   1 
ATOM   13487 C  CA  . VAL F 1 269 ? 36.738  9.307   59.417  1.00 26.23  ? 269 VAL F CA  1 
ATOM   13488 C  C   . VAL F 1 269 ? 37.869  8.874   58.492  1.00 31.76  ? 269 VAL F C   1 
ATOM   13489 O  O   . VAL F 1 269 ? 38.545  7.836   58.731  1.00 28.99  ? 269 VAL F O   1 
ATOM   13490 C  CB  . VAL F 1 269 ? 35.365  9.102   58.774  1.00 30.32  ? 269 VAL F CB  1 
ATOM   13491 C  CG1 . VAL F 1 269 ? 35.117  7.650   58.387  1.00 28.53  ? 269 VAL F CG1 1 
ATOM   13492 C  CG2 . VAL F 1 269 ? 34.235  9.558   59.688  1.00 33.25  ? 269 VAL F CG2 1 
ATOM   13493 N  N   . THR F 1 270 ? 38.089  9.690   57.442  1.00 28.45  ? 270 THR F N   1 
ATOM   13494 C  CA  . THR F 1 270 ? 39.117  9.348   56.469  1.00 28.83  ? 270 THR F CA  1 
ATOM   13495 C  C   . THR F 1 270 ? 40.514  9.259   57.121  1.00 24.42  ? 270 THR F C   1 
ATOM   13496 O  O   . THR F 1 270 ? 41.332  8.387   56.806  1.00 20.29  ? 270 THR F O   1 
ATOM   13497 C  CB  . THR F 1 270 ? 39.074  10.370  55.335  1.00 28.04  ? 270 THR F CB  1 
ATOM   13498 O  OG1 . THR F 1 270 ? 37.735  10.573  54.913  1.00 28.13  ? 270 THR F OG1 1 
ATOM   13499 C  CG2 . THR F 1 270 ? 39.848  9.834   54.149  1.00 31.71  ? 270 THR F CG2 1 
ATOM   13500 N  N   . GLU F 1 271 ? 40.804  10.191  58.042  1.00 29.65  ? 271 GLU F N   1 
ATOM   13501 C  CA  . GLU F 1 271 ? 42.114  10.281  58.695  1.00 28.92  ? 271 GLU F CA  1 
ATOM   13502 C  C   . GLU F 1 271 ? 42.342  9.082   59.623  1.00 25.56  ? 271 GLU F C   1 
ATOM   13503 O  O   . GLU F 1 271 ? 43.463  8.557   59.742  1.00 28.50  ? 271 GLU F O   1 
ATOM   13504 C  CB  . GLU F 1 271 ? 42.297  11.599  59.460  1.00 30.65  ? 271 GLU F CB  1 
ATOM   13505 C  CG  . GLU F 1 271 ? 42.614  12.775  58.557  1.00 28.24  ? 271 GLU F CG  1 
ATOM   13506 C  CD  . GLU F 1 271 ? 42.426  14.173  59.113  1.00 33.15  ? 271 GLU F CD  1 
ATOM   13507 O  OE1 . GLU F 1 271 ? 41.826  14.273  60.205  1.00 32.15  ? 271 GLU F OE1 1 
ATOM   13508 O  OE2 . GLU F 1 271 ? 42.862  15.139  58.358  1.00 34.00  ? 271 GLU F OE2 1 
ATOM   13509 N  N   . THR F 1 272 ? 41.276  8.568   60.238  1.00 26.05  ? 272 THR F N   1 
ATOM   13510 C  CA  . THR F 1 272 ? 41.427  7.373   61.045  1.00 26.24  ? 272 THR F CA  1 
ATOM   13511 C  C   . THR F 1 272 ? 41.862  6.198   60.188  1.00 28.66  ? 272 THR F C   1 
ATOM   13512 O  O   . THR F 1 272 ? 42.770  5.450   60.571  1.00 29.05  ? 272 THR F O   1 
ATOM   13513 C  CB  . THR F 1 272 ? 40.114  7.046   61.704  1.00 29.78  ? 272 THR F CB  1 
ATOM   13514 O  OG1 . THR F 1 272 ? 39.999  8.134   62.587  1.00 30.02  ? 272 THR F OG1 1 
ATOM   13515 C  CG2 . THR F 1 272 ? 40.148  5.739   62.455  1.00 34.01  ? 272 THR F CG2 1 
ATOM   13516 N  N   . MET F 1 273 ? 41.174  6.042   59.051  1.00 27.51  ? 273 MET F N   1 
ATOM   13517 C  CA  . MET F 1 273 ? 41.495  4.948   58.156  1.00 27.79  ? 273 MET F CA  1 
ATOM   13518 C  C   . MET F 1 273 ? 42.943  5.060   57.718  1.00 26.64  ? 273 MET F C   1 
ATOM   13519 O  O   . MET F 1 273 ? 43.659  4.057   57.640  1.00 23.64  ? 273 MET F O   1 
ATOM   13520 C  CB  . MET F 1 273 ? 40.532  4.978   56.961  1.00 32.25  ? 273 MET F CB  1 
ATOM   13521 C  CG  . MET F 1 273 ? 39.097  4.601   57.309  1.00 28.77  ? 273 MET F CG  1 
ATOM   13522 S  SD  . MET F 1 273 ? 38.027  4.793   55.872  1.00 28.82  ? 273 MET F SD  1 
ATOM   13523 C  CE  . MET F 1 273 ? 36.448  4.276   56.552  1.00 30.40  ? 273 MET F CE  1 
ATOM   13524 N  N   . LEU F 1 274 ? 43.367  6.295   57.408  1.00 24.85  ? 274 LEU F N   1 
ATOM   13525 C  CA  . LEU F 1 274 ? 44.729  6.490   56.941  1.00 29.76  ? 274 LEU F CA  1 
ATOM   13526 C  C   . LEU F 1 274 ? 45.744  6.117   58.036  1.00 30.85  ? 274 LEU F C   1 
ATOM   13527 O  O   . LEU F 1 274 ? 46.777  5.520   57.717  1.00 27.97  ? 274 LEU F O   1 
ATOM   13528 C  CB  . LEU F 1 274 ? 44.941  7.944   56.477  1.00 29.76  ? 274 LEU F CB  1 
ATOM   13529 C  CG  . LEU F 1 274 ? 44.416  8.261   55.084  1.00 33.05  ? 274 LEU F CG  1 
ATOM   13530 C  CD1 . LEU F 1 274 ? 44.437  9.729   54.817  1.00 30.74  ? 274 LEU F CD1 1 
ATOM   13531 C  CD2 . LEU F 1 274 ? 45.209  7.509   54.016  1.00 33.71  ? 274 LEU F CD2 1 
ATOM   13532 N  N   . GLU F 1 275 ? 45.507  6.559   59.297  1.00 28.90  ? 275 GLU F N   1 
ATOM   13533 C  CA  . GLU F 1 275 ? 46.408  6.212   60.396  1.00 29.37  ? 275 GLU F CA  1 
ATOM   13534 C  C   . GLU F 1 275 ? 46.540  4.689   60.542  1.00 28.33  ? 275 GLU F C   1 
ATOM   13535 O  O   . GLU F 1 275 ? 47.652  4.172   60.614  1.00 33.10  ? 275 GLU F O   1 
ATOM   13536 C  CB  . GLU F 1 275 ? 45.910  6.684   61.750  1.00 33.25  ? 275 GLU F CB  1 
ATOM   13537 C  CG  . GLU F 1 275 ? 46.111  8.168   61.989  1.00 43.25  ? 275 GLU F CG  1 
ATOM   13538 C  CD  . GLU F 1 275 ? 45.398  8.684   63.226  1.00 46.64  ? 275 GLU F CD  1 
ATOM   13539 O  OE1 . GLU F 1 275 ? 45.244  7.949   64.211  1.00 55.56  ? 275 GLU F OE1 1 
ATOM   13540 O  OE2 . GLU F 1 275 ? 44.980  9.842   63.198  1.00 50.40  ? 275 GLU F OE2 1 
ATOM   13541 N  N   . ARG F 1 276 ? 45.407  3.976   60.577  1.00 28.77  ? 276 ARG F N   1 
ATOM   13542 C  CA  . ARG F 1 276 ? 45.408  2.515   60.587  1.00 31.31  ? 276 ARG F CA  1 
ATOM   13543 C  C   . ARG F 1 276 ? 46.247  1.911   59.461  1.00 33.86  ? 276 ARG F C   1 
ATOM   13544 O  O   . ARG F 1 276 ? 46.999  0.988   59.700  1.00 32.12  ? 276 ARG F O   1 
ATOM   13545 C  CB  . ARG F 1 276 ? 43.977  1.985   60.563  1.00 34.65  ? 276 ARG F CB  1 
ATOM   13546 C  CG  . ARG F 1 276 ? 43.428  2.288   61.960  1.00 38.87  ? 276 ARG F CG  1 
ATOM   13547 C  CD  . ARG F 1 276 ? 41.930  2.344   62.048  1.00 45.36  ? 276 ARG F CD  1 
ATOM   13548 N  NE  . ARG F 1 276 ? 41.335  1.075   61.611  1.00 56.66  ? 276 ARG F NE  1 
ATOM   13549 C  CZ  . ARG F 1 276 ? 41.191  -0.005  62.373  1.00 59.11  ? 276 ARG F CZ  1 
ATOM   13550 N  NH1 . ARG F 1 276 ? 41.447  0.104   63.655  1.00 73.33  ? 276 ARG F NH1 1 
ATOM   13551 N  NH2 . ARG F 1 276 ? 40.733  -1.150  61.869  1.00 44.34  ? 276 ARG F NH2 1 
ATOM   13552 N  N   . MET F 1 277 ? 46.147  2.437   58.242  1.00 32.89  ? 277 MET F N   1 
ATOM   13553 C  CA  . MET F 1 277 ? 46.895  1.905   57.111  1.00 30.11  ? 277 MET F CA  1 
ATOM   13554 C  C   . MET F 1 277 ? 48.388  2.154   57.262  1.00 29.00  ? 277 MET F C   1 
ATOM   13555 O  O   . MET F 1 277 ? 49.189  1.286   56.991  1.00 25.80  ? 277 MET F O   1 
ATOM   13556 C  CB  . MET F 1 277 ? 46.410  2.572   55.805  1.00 32.63  ? 277 MET F CB  1 
ATOM   13557 C  CG  . MET F 1 277 ? 44.989  2.129   55.361  1.00 35.05  ? 277 MET F CG  1 
ATOM   13558 S  SD  . MET F 1 277 ? 44.402  3.030   53.928  1.00 29.14  ? 277 MET F SD  1 
ATOM   13559 C  CE  . MET F 1 277 ? 45.683  2.683   52.703  1.00 31.49  ? 277 MET F CE  1 
ATOM   13560 N  N   . PHE F 1 278 ? 48.763  3.391   57.598  1.00 35.69  ? 278 PHE F N   1 
ATOM   13561 C  CA  . PHE F 1 278 ? 50.173  3.818   57.550  1.00 33.95  ? 278 PHE F CA  1 
ATOM   13562 C  C   . PHE F 1 278 ? 50.873  3.536   58.887  1.00 32.57  ? 278 PHE F C   1 
ATOM   13563 O  O   . PHE F 1 278 ? 52.037  3.234   58.906  1.00 27.00  ? 278 PHE F O   1 
ATOM   13564 C  CB  . PHE F 1 278 ? 50.323  5.316   57.196  1.00 34.25  ? 278 PHE F CB  1 
ATOM   13565 C  CG  . PHE F 1 278 ? 50.157  5.552   55.704  1.00 31.03  ? 278 PHE F CG  1 
ATOM   13566 C  CD1 . PHE F 1 278 ? 48.911  5.647   55.105  1.00 29.39  ? 278 PHE F CD1 1 
ATOM   13567 C  CD2 . PHE F 1 278 ? 51.260  5.566   54.886  1.00 31.26  ? 278 PHE F CD2 1 
ATOM   13568 C  CE1 . PHE F 1 278 ? 48.776  5.774   53.730  1.00 29.44  ? 278 PHE F CE1 1 
ATOM   13569 C  CE2 . PHE F 1 278 ? 51.108  5.667   53.499  1.00 31.90  ? 278 PHE F CE2 1 
ATOM   13570 C  CZ  . PHE F 1 278 ? 49.871  5.766   52.928  1.00 29.93  ? 278 PHE F CZ  1 
ATOM   13571 N  N   . LEU F 1 279 ? 50.154  3.654   59.999  1.00 34.30  ? 279 LEU F N   1 
ATOM   13572 C  CA  . LEU F 1 279 ? 50.764  3.540   61.310  1.00 38.17  ? 279 LEU F CA  1 
ATOM   13573 C  C   . LEU F 1 279 ? 50.459  2.190   61.947  1.00 36.61  ? 279 LEU F C   1 
ATOM   13574 O  O   . LEU F 1 279 ? 51.232  1.728   62.763  1.00 41.88  ? 279 LEU F O   1 
ATOM   13575 C  CB  . LEU F 1 279 ? 50.320  4.674   62.224  1.00 38.45  ? 279 LEU F CB  1 
ATOM   13576 C  CG  . LEU F 1 279 ? 50.626  6.073   61.680  1.00 38.61  ? 279 LEU F CG  1 
ATOM   13577 C  CD1 . LEU F 1 279 ? 50.062  7.044   62.649  1.00 36.62  ? 279 LEU F CD1 1 
ATOM   13578 C  CD2 . LEU F 1 279 ? 52.089  6.357   61.418  1.00 40.25  ? 279 LEU F CD2 1 
ATOM   13579 N  N   . GLY F 1 280 ? 49.400  1.507   61.580  1.00 33.50  ? 280 GLY F N   1 
ATOM   13580 C  CA  . GLY F 1 280 ? 49.259  0.145   62.072  1.00 32.77  ? 280 GLY F CA  1 
ATOM   13581 C  C   . GLY F 1 280 ? 48.345  0.124   63.266  1.00 33.47  ? 280 GLY F C   1 
ATOM   13582 O  O   . GLY F 1 280 ? 47.756  1.131   63.545  1.00 38.18  ? 280 GLY F O   1 
ATOM   13583 N  N   . THR F 1 281 ? 48.151  -1.038  63.871  1.00 40.01  ? 281 THR F N   1 
ATOM   13584 C  CA  . THR F 1 281 ? 47.269  -1.251  65.020  1.00 42.26  ? 281 THR F CA  1 
ATOM   13585 C  C   . THR F 1 281 ? 48.005  -2.220  65.922  1.00 42.16  ? 281 THR F C   1 
ATOM   13586 O  O   . THR F 1 281 ? 49.135  -2.552  65.613  1.00 47.88  ? 281 THR F O   1 
ATOM   13587 C  CB  . THR F 1 281 ? 45.910  -1.862  64.648  1.00 42.71  ? 281 THR F CB  1 
ATOM   13588 O  OG1 . THR F 1 281 ? 46.200  -3.162  64.069  1.00 36.10  ? 281 THR F OG1 1 
ATOM   13589 C  CG2 . THR F 1 281 ? 45.123  -0.848  63.826  1.00 37.68  ? 281 THR F CG2 1 
ATOM   13590 N  N   . ALA F 1 282 ? 47.345  -2.700  66.981  1.00 47.08  ? 282 ALA F N   1 
ATOM   13591 C  CA  . ALA F 1 282 ? 47.917  -3.717  67.852  1.00 49.80  ? 282 ALA F CA  1 
ATOM   13592 C  C   . ALA F 1 282 ? 48.325  -4.950  67.041  1.00 49.36  ? 282 ALA F C   1 
ATOM   13593 O  O   . ALA F 1 282 ? 49.461  -5.401  67.189  1.00 46.56  ? 282 ALA F O   1 
ATOM   13594 C  CB  . ALA F 1 282 ? 46.931  -4.076  68.951  1.00 44.93  ? 282 ALA F CB  1 
ATOM   13595 N  N   . SER F 1 283 ? 47.448  -5.439  66.142  1.00 46.91  ? 283 SER F N   1 
ATOM   13596 C  CA  . SER F 1 283 ? 47.722  -6.706  65.450  1.00 58.95  ? 283 SER F CA  1 
ATOM   13597 C  C   . SER F 1 283 ? 48.214  -6.551  64.001  1.00 54.69  ? 283 SER F C   1 
ATOM   13598 O  O   . SER F 1 283 ? 48.446  -7.553  63.325  1.00 46.04  ? 283 SER F O   1 
ATOM   13599 C  CB  . SER F 1 283 ? 46.557  -7.667  65.499  1.00 59.10  ? 283 SER F CB  1 
ATOM   13600 O  OG  . SER F 1 283 ? 45.397  -6.918  65.215  1.00 59.25  ? 283 SER F OG  1 
ATOM   13601 N  N   . ALA F 1 284 ? 48.447  -5.321  63.525  1.00 55.19  ? 284 ALA F N   1 
ATOM   13602 C  CA  . ALA F 1 284 ? 48.892  -5.177  62.154  1.00 52.36  ? 284 ALA F CA  1 
ATOM   13603 C  C   . ALA F 1 284 ? 49.948  -4.082  62.047  1.00 40.88  ? 284 ALA F C   1 
ATOM   13604 O  O   . ALA F 1 284 ? 49.750  -2.936  62.451  1.00 35.36  ? 284 ALA F O   1 
ATOM   13605 C  CB  . ALA F 1 284 ? 47.669  -4.886  61.330  1.00 58.84  ? 284 ALA F CB  1 
ATOM   13606 N  N   . PRO F 1 285 ? 51.138  -4.397  61.514  1.00 37.32  ? 285 PRO F N   1 
ATOM   13607 C  CA  . PRO F 1 285 ? 52.159  -3.356  61.352  1.00 38.46  ? 285 PRO F CA  1 
ATOM   13608 C  C   . PRO F 1 285 ? 51.724  -2.199  60.438  1.00 42.85  ? 285 PRO F C   1 
ATOM   13609 O  O   . PRO F 1 285 ? 51.990  -1.044  60.723  1.00 42.88  ? 285 PRO F O   1 
ATOM   13610 C  CB  . PRO F 1 285 ? 53.379  -4.141  60.818  1.00 38.89  ? 285 PRO F CB  1 
ATOM   13611 C  CG  . PRO F 1 285 ? 52.829  -5.420  60.313  1.00 43.05  ? 285 PRO F CG  1 
ATOM   13612 C  CD  . PRO F 1 285 ? 51.560  -5.734  61.094  1.00 39.19  ? 285 PRO F CD  1 
ATOM   13613 N  N   . HIS F 1 286 ? 51.068  -2.517  59.315  1.00 43.89  ? 286 HIS F N   1 
ATOM   13614 C  CA  . HIS F 1 286 ? 50.524  -1.528  58.376  1.00 40.98  ? 286 HIS F CA  1 
ATOM   13615 C  C   . HIS F 1 286 ? 49.688  -2.286  57.344  1.00 36.10  ? 286 HIS F C   1 
ATOM   13616 O  O   . HIS F 1 286 ? 49.710  -3.520  57.332  1.00 32.05  ? 286 HIS F O   1 
ATOM   13617 C  CB  . HIS F 1 286 ? 51.635  -0.754  57.673  1.00 30.96  ? 286 HIS F CB  1 
ATOM   13618 C  CG  . HIS F 1 286 ? 52.615  -1.641  56.994  1.00 34.14  ? 286 HIS F CG  1 
ATOM   13619 N  ND1 . HIS F 1 286 ? 53.890  -1.819  57.473  1.00 30.29  ? 286 HIS F ND1 1 
ATOM   13620 C  CD2 . HIS F 1 286 ? 52.554  -2.341  55.846  1.00 35.24  ? 286 HIS F CD2 1 
ATOM   13621 C  CE1 . HIS F 1 286 ? 54.573  -2.573  56.603  1.00 33.88  ? 286 HIS F CE1 1 
ATOM   13622 N  NE2 . HIS F 1 286 ? 53.793  -2.918  55.605  1.00 36.99  ? 286 HIS F NE2 1 
ATOM   13623 N  N   . ASP F 1 287 ? 48.957  -1.543  56.505  1.00 33.46  ? 287 ASP F N   1 
ATOM   13624 C  CA  . ASP F 1 287 ? 48.165  -2.115  55.429  1.00 27.92  ? 287 ASP F CA  1 
ATOM   13625 C  C   . ASP F 1 287 ? 49.059  -2.762  54.376  1.00 23.24  ? 287 ASP F C   1 
ATOM   13626 O  O   . ASP F 1 287 ? 49.849  -2.106  53.764  1.00 23.40  ? 287 ASP F O   1 
ATOM   13627 C  CB  . ASP F 1 287 ? 47.261  -1.031  54.855  1.00 28.86  ? 287 ASP F CB  1 
ATOM   13628 C  CG  . ASP F 1 287 ? 46.196  -1.498  53.871  1.00 26.32  ? 287 ASP F CG  1 
ATOM   13629 O  OD1 . ASP F 1 287 ? 46.402  -2.545  53.250  1.00 25.20  ? 287 ASP F OD1 1 
ATOM   13630 O  OD2 . ASP F 1 287 ? 45.170  -0.823  53.764  1.00 25.75  ? 287 ASP F OD2 1 
ATOM   13631 N  N   . ARG F 1 288 ? 48.879  -4.038  54.094  1.00 21.50  ? 288 ARG F N   1 
ATOM   13632 C  CA  . ARG F 1 288 ? 49.710  -4.736  53.128  1.00 26.15  ? 288 ARG F CA  1 
ATOM   13633 C  C   . ARG F 1 288 ? 49.615  -4.133  51.714  1.00 26.73  ? 288 ARG F C   1 
ATOM   13634 O  O   . ARG F 1 288 ? 50.513  -4.317  50.881  1.00 24.39  ? 288 ARG F O   1 
ATOM   13635 C  CB  . ARG F 1 288 ? 49.314  -6.225  53.097  1.00 32.80  ? 288 ARG F CB  1 
ATOM   13636 C  CG  . ARG F 1 288 ? 49.879  -6.980  54.305  1.00 39.37  ? 288 ARG F CG  1 
ATOM   13637 C  CD  . ARG F 1 288 ? 51.371  -7.292  54.105  1.00 37.78  ? 288 ARG F CD  1 
ATOM   13638 N  NE  . ARG F 1 288 ? 51.530  -8.431  53.175  1.00 42.26  ? 288 ARG F NE  1 
ATOM   13639 C  CZ  . ARG F 1 288 ? 52.447  -8.544  52.203  1.00 44.62  ? 288 ARG F CZ  1 
ATOM   13640 N  NH1 . ARG F 1 288 ? 53.367  -7.604  51.996  1.00 40.95  ? 288 ARG F NH1 1 
ATOM   13641 N  NH2 . ARG F 1 288 ? 52.457  -9.622  51.439  1.00 49.46  ? 288 ARG F NH2 1 
ATOM   13642 N  N   . ILE F 1 289 ? 48.534  -3.411  51.419  1.00 23.85  ? 289 ILE F N   1 
ATOM   13643 C  CA  . ILE F 1 289 ? 48.421  -2.855  50.090  1.00 28.35  ? 289 ILE F CA  1 
ATOM   13644 C  C   . ILE F 1 289 ? 49.553  -1.856  49.856  1.00 27.91  ? 289 ILE F C   1 
ATOM   13645 O  O   . ILE F 1 289 ? 49.929  -1.649  48.692  1.00 26.83  ? 289 ILE F O   1 
ATOM   13646 C  CB  . ILE F 1 289 ? 47.040  -2.213  49.876  1.00 34.77  ? 289 ILE F CB  1 
ATOM   13647 C  CG1 . ILE F 1 289 ? 46.591  -2.358  48.399  1.00 33.39  ? 289 ILE F CG1 1 
ATOM   13648 C  CG2 . ILE F 1 289 ? 46.978  -0.754  50.404  1.00 35.75  ? 289 ILE F CG2 1 
ATOM   13649 C  CD1 . ILE F 1 289 ? 45.194  -1.791  48.114  1.00 31.37  ? 289 ILE F CD1 1 
ATOM   13650 N  N   . LEU F 1 290 ? 50.083  -1.247  50.934  1.00 25.58  ? 290 LEU F N   1 
ATOM   13651 C  CA  . LEU F 1 290 ? 51.100  -0.204  50.807  1.00 26.19  ? 290 LEU F CA  1 
ATOM   13652 C  C   . LEU F 1 290 ? 52.457  -0.806  50.469  1.00 27.56  ? 290 LEU F C   1 
ATOM   13653 O  O   . LEU F 1 290 ? 53.373  -0.114  50.027  1.00 27.02  ? 290 LEU F O   1 
ATOM   13654 C  CB  . LEU F 1 290 ? 51.218  0.628   52.079  1.00 24.52  ? 290 LEU F CB  1 
ATOM   13655 C  CG  . LEU F 1 290 ? 49.960  1.367   52.497  1.00 28.22  ? 290 LEU F CG  1 
ATOM   13656 C  CD1 . LEU F 1 290 ? 50.137  1.997   53.866  1.00 29.84  ? 290 LEU F CD1 1 
ATOM   13657 C  CD2 . LEU F 1 290 ? 49.653  2.453   51.419  1.00 30.79  ? 290 LEU F CD2 1 
ATOM   13658 N  N   . ASP F 1 291 ? 52.573  -2.126  50.662  1.00 28.41  ? 291 ASP F N   1 
ATOM   13659 C  CA  . ASP F 1 291 ? 53.742  -2.835  50.176  1.00 27.56  ? 291 ASP F CA  1 
ATOM   13660 C  C   . ASP F 1 291 ? 53.771  -2.857  48.646  1.00 29.93  ? 291 ASP F C   1 
ATOM   13661 O  O   . ASP F 1 291 ? 54.804  -3.181  48.117  1.00 30.34  ? 291 ASP F O   1 
ATOM   13662 C  CB  . ASP F 1 291 ? 53.905  -4.196  50.842  1.00 29.08  ? 291 ASP F CB  1 
ATOM   13663 C  CG  . ASP F 1 291 ? 54.224  -4.144  52.351  1.00 35.00  ? 291 ASP F CG  1 
ATOM   13664 O  OD1 . ASP F 1 291 ? 54.791  -3.139  52.881  1.00 31.98  ? 291 ASP F OD1 1 
ATOM   13665 O  OD2 . ASP F 1 291 ? 53.793  -5.044  53.053  1.00 36.71  ? 291 ASP F OD2 1 
ATOM   13666 N  N   . PHE F 1 292 ? 52.684  -2.506  47.925  1.00 26.65  ? 292 PHE F N   1 
ATOM   13667 C  CA  . PHE F 1 292 ? 52.683  -2.489  46.470  1.00 25.36  ? 292 PHE F CA  1 
ATOM   13668 C  C   . PHE F 1 292 ? 52.199  -1.149  45.916  1.00 26.54  ? 292 PHE F C   1 
ATOM   13669 O  O   . PHE F 1 292 ? 51.996  -1.015  44.720  1.00 24.82  ? 292 PHE F O   1 
ATOM   13670 C  CB  . PHE F 1 292 ? 51.776  -3.608  46.004  1.00 25.26  ? 292 PHE F CB  1 
ATOM   13671 C  CG  . PHE F 1 292 ? 52.242  -4.935  46.562  1.00 25.42  ? 292 PHE F CG  1 
ATOM   13672 C  CD1 . PHE F 1 292 ? 53.284  -5.635  45.954  1.00 27.30  ? 292 PHE F CD1 1 
ATOM   13673 C  CD2 . PHE F 1 292 ? 51.688  -5.434  47.735  1.00 28.97  ? 292 PHE F CD2 1 
ATOM   13674 C  CE1 . PHE F 1 292 ? 53.737  -6.859  46.464  1.00 26.87  ? 292 PHE F CE1 1 
ATOM   13675 C  CE2 . PHE F 1 292 ? 52.113  -6.679  48.230  1.00 33.36  ? 292 PHE F CE2 1 
ATOM   13676 C  CZ  . PHE F 1 292 ? 53.125  -7.405  47.570  1.00 28.27  ? 292 PHE F CZ  1 
ATOM   13677 N  N   . SER F 1 293 ? 52.073  -0.139  46.783  1.00 25.58  ? 293 SER F N   1 
ATOM   13678 C  CA  . SER F 1 293 ? 51.499  1.124   46.398  1.00 25.05  ? 293 SER F CA  1 
ATOM   13679 C  C   . SER F 1 293 ? 52.225  2.248   47.126  1.00 25.70  ? 293 SER F C   1 
ATOM   13680 O  O   . SER F 1 293 ? 52.221  2.234   48.333  1.00 32.73  ? 293 SER F O   1 
ATOM   13681 C  CB  . SER F 1 293 ? 50.017  1.133   46.739  1.00 25.22  ? 293 SER F CB  1 
ATOM   13682 O  OG  . SER F 1 293 ? 49.388  -0.102  46.378  1.00 24.87  ? 293 SER F OG  1 
ATOM   13683 N  N   . THR F 1 294 ? 52.706  3.269   46.393  1.00 24.87  ? 294 THR F N   1 
ATOM   13684 C  CA  . THR F 1 294 ? 53.371  4.420   46.969  1.00 24.43  ? 294 THR F CA  1 
ATOM   13685 C  C   . THR F 1 294 ? 52.546  5.661   46.700  1.00 25.22  ? 294 THR F C   1 
ATOM   13686 O  O   . THR F 1 294 ? 52.266  5.934   45.536  1.00 25.83  ? 294 THR F O   1 
ATOM   13687 C  CB  . THR F 1 294 ? 54.740  4.602   46.314  1.00 27.60  ? 294 THR F CB  1 
ATOM   13688 O  OG1 . THR F 1 294 ? 55.503  3.499   46.742  1.00 28.79  ? 294 THR F OG1 1 
ATOM   13689 C  CG2 . THR F 1 294 ? 55.534  5.797   46.803  1.00 26.59  ? 294 THR F CG2 1 
ATOM   13690 N  N   . ALA F 1 295 ? 52.211  6.406   47.764  1.00 22.73  ? 295 ALA F N   1 
ATOM   13691 C  CA  . ALA F 1 295 ? 51.457  7.646   47.647  1.00 25.04  ? 295 ALA F CA  1 
ATOM   13692 C  C   . ALA F 1 295 ? 52.431  8.718   47.221  1.00 27.92  ? 295 ALA F C   1 
ATOM   13693 O  O   . ALA F 1 295 ? 53.428  8.831   47.859  1.00 31.22  ? 295 ALA F O   1 
ATOM   13694 C  CB  . ALA F 1 295 ? 50.852  8.038   48.984  1.00 25.33  ? 295 ALA F CB  1 
ATOM   13695 N  N   . VAL F 1 296 ? 52.174  9.508   46.180  1.00 32.39  ? 296 VAL F N   1 
ATOM   13696 C  CA  . VAL F 1 296 ? 53.066  10.601  45.812  1.00 30.23  ? 296 VAL F CA  1 
ATOM   13697 C  C   . VAL F 1 296 ? 52.411  11.976  45.928  1.00 30.16  ? 296 VAL F C   1 
ATOM   13698 O  O   . VAL F 1 296 ? 53.097  12.943  45.697  1.00 31.30  ? 296 VAL F O   1 
ATOM   13699 C  CB  . VAL F 1 296 ? 53.611  10.333  44.413  1.00 26.87  ? 296 VAL F CB  1 
ATOM   13700 C  CG1 . VAL F 1 296 ? 54.112  8.893   44.339  1.00 28.44  ? 296 VAL F CG1 1 
ATOM   13701 C  CG2 . VAL F 1 296 ? 52.603  10.531  43.341  1.00 28.27  ? 296 VAL F CG2 1 
ATOM   13702 N  N   . THR F 1 297 ? 51.112  12.045  46.270  1.00 25.44  ? 297 THR F N   1 
ATOM   13703 C  CA  . THR F 1 297 ? 50.465  13.294  46.585  1.00 24.56  ? 297 THR F CA  1 
ATOM   13704 C  C   . THR F 1 297 ? 49.551  13.034  47.758  1.00 22.73  ? 297 THR F C   1 
ATOM   13705 O  O   . THR F 1 297 ? 49.237  11.894  48.084  1.00 25.68  ? 297 THR F O   1 
ATOM   13706 C  CB  . THR F 1 297 ? 49.638  13.850  45.419  1.00 27.52  ? 297 THR F CB  1 
ATOM   13707 O  OG1 . THR F 1 297 ? 48.460  13.088  45.131  1.00 24.25  ? 297 THR F OG1 1 
ATOM   13708 C  CG2 . THR F 1 297 ? 50.449  14.007  44.143  1.00 29.18  ? 297 THR F CG2 1 
ATOM   13709 N  N   . GLY F 1 298 ? 49.066  14.117  48.337  1.00 23.54  ? 298 GLY F N   1 
ATOM   13710 C  CA  . GLY F 1 298 ? 48.143  14.020  49.452  1.00 21.42  ? 298 GLY F CA  1 
ATOM   13711 C  C   . GLY F 1 298 ? 47.608  15.404  49.782  1.00 20.92  ? 298 GLY F C   1 
ATOM   13712 O  O   . GLY F 1 298 ? 48.365  16.311  50.063  1.00 23.27  ? 298 GLY F O   1 
ATOM   13713 N  N   . SER F 1 299 ? 46.306  15.588  49.719  1.00 21.68  ? 299 SER F N   1 
ATOM   13714 C  CA  . SER F 1 299 ? 45.717  16.881  50.012  1.00 22.45  ? 299 SER F CA  1 
ATOM   13715 C  C   . SER F 1 299 ? 44.292  16.641  50.487  1.00 22.14  ? 299 SER F C   1 
ATOM   13716 O  O   . SER F 1 299 ? 43.679  15.600  50.198  1.00 19.01  ? 299 SER F O   1 
ATOM   13717 C  CB  . SER F 1 299 ? 45.686  17.817  48.816  1.00 24.38  ? 299 SER F CB  1 
ATOM   13718 O  OG  . SER F 1 299 ? 46.864  17.807  48.059  1.00 25.72  ? 299 SER F OG  1 
ATOM   13719 N  N   . LEU F 1 300 ? 43.786  17.678  51.145  1.00 22.55  ? 300 LEU F N   1 
ATOM   13720 C  CA  . LEU F 1 300 ? 42.473  17.653  51.747  1.00 23.46  ? 300 LEU F CA  1 
ATOM   13721 C  C   . LEU F 1 300 ? 41.751  18.911  51.301  1.00 22.30  ? 300 LEU F C   1 
ATOM   13722 O  O   . LEU F 1 300 ? 42.323  19.981  51.317  1.00 22.31  ? 300 LEU F O   1 
ATOM   13723 C  CB  . LEU F 1 300 ? 42.618  17.564  53.270  1.00 27.88  ? 300 LEU F CB  1 
ATOM   13724 C  CG  . LEU F 1 300 ? 41.339  17.367  54.108  1.00 33.87  ? 300 LEU F CG  1 
ATOM   13725 C  CD1 . LEU F 1 300 ? 41.704  17.276  55.591  1.00 39.06  ? 300 LEU F CD1 1 
ATOM   13726 C  CD2 . LEU F 1 300 ? 40.357  18.432  54.060  1.00 36.62  ? 300 LEU F CD2 1 
ATOM   13727 N  N   . PHE F 1 301 ? 40.484  18.767  50.913  1.00 25.81  ? 301 PHE F N   1 
ATOM   13728 C  CA  . PHE F 1 301 ? 39.681  19.876  50.445  1.00 23.09  ? 301 PHE F CA  1 
ATOM   13729 C  C   . PHE F 1 301 ? 38.279  19.784  51.013  1.00 21.87  ? 301 PHE F C   1 
ATOM   13730 O  O   . PHE F 1 301 ? 37.773  18.693  51.267  1.00 22.36  ? 301 PHE F O   1 
ATOM   13731 C  CB  . PHE F 1 301 ? 39.493  19.783  48.940  1.00 24.60  ? 301 PHE F CB  1 
ATOM   13732 C  CG  . PHE F 1 301 ? 40.792  19.749  48.174  1.00 22.34  ? 301 PHE F CG  1 
ATOM   13733 C  CD1 . PHE F 1 301 ? 41.403  20.934  47.791  1.00 22.39  ? 301 PHE F CD1 1 
ATOM   13734 C  CD2 . PHE F 1 301 ? 41.399  18.549  47.897  1.00 21.47  ? 301 PHE F CD2 1 
ATOM   13735 C  CE1 . PHE F 1 301 ? 42.608  20.904  47.126  1.00 24.82  ? 301 PHE F CE1 1 
ATOM   13736 C  CE2 . PHE F 1 301 ? 42.604  18.529  47.230  1.00 23.66  ? 301 PHE F CE2 1 
ATOM   13737 C  CZ  . PHE F 1 301 ? 43.202  19.691  46.848  1.00 23.65  ? 301 PHE F CZ  1 
ATOM   13738 N  N   . PHE F 1 302 ? 37.682  20.958  51.153  1.00 19.61  ? 302 PHE F N   1 
ATOM   13739 C  CA  . PHE F 1 302 ? 36.277  21.144  51.445  1.00 21.04  ? 302 PHE F CA  1 
ATOM   13740 C  C   . PHE F 1 302 ? 35.547  21.469  50.137  1.00 21.98  ? 302 PHE F C   1 
ATOM   13741 O  O   . PHE F 1 302 ? 35.920  22.412  49.426  1.00 19.92  ? 302 PHE F O   1 
ATOM   13742 C  CB  . PHE F 1 302 ? 36.060  22.269  52.479  1.00 21.09  ? 302 PHE F CB  1 
ATOM   13743 C  CG  . PHE F 1 302 ? 34.598  22.372  52.913  1.00 21.90  ? 302 PHE F CG  1 
ATOM   13744 C  CD1 . PHE F 1 302 ? 33.979  21.344  53.663  1.00 23.99  ? 302 PHE F CD1 1 
ATOM   13745 C  CD2 . PHE F 1 302 ? 33.816  23.439  52.485  1.00 25.43  ? 302 PHE F CD2 1 
ATOM   13746 C  CE1 . PHE F 1 302 ? 32.636  21.410  53.982  1.00 23.57  ? 302 PHE F CE1 1 
ATOM   13747 C  CE2 . PHE F 1 302 ? 32.465  23.498  52.815  1.00 26.29  ? 302 PHE F CE2 1 
ATOM   13748 C  CZ  . PHE F 1 302 ? 31.886  22.498  53.571  1.00 23.82  ? 302 PHE F CZ  1 
ATOM   13749 N  N   . THR F 1 303 ? 34.474  20.704  49.885  1.00 21.76  ? 303 THR F N   1 
ATOM   13750 C  CA  . THR F 1 303 ? 33.652  20.868  48.707  1.00 22.09  ? 303 THR F CA  1 
ATOM   13751 C  C   . THR F 1 303 ? 32.321  21.453  49.189  1.00 22.85  ? 303 THR F C   1 
ATOM   13752 O  O   . THR F 1 303 ? 31.423  20.738  49.632  1.00 25.07  ? 303 THR F O   1 
ATOM   13753 C  CB  . THR F 1 303 ? 33.458  19.553  47.945  1.00 22.65  ? 303 THR F CB  1 
ATOM   13754 O  OG1 . THR F 1 303 ? 32.836  18.563  48.741  1.00 25.21  ? 303 THR F OG1 1 
ATOM   13755 C  CG2 . THR F 1 303 ? 34.739  18.886  47.506  1.00 24.48  ? 303 THR F CG2 1 
ATOM   13756 N  N   . PRO F 1 304 ? 32.148  22.788  49.091  1.00 25.54  ? 304 PRO F N   1 
ATOM   13757 C  CA  . PRO F 1 304 ? 30.964  23.453  49.585  1.00 28.44  ? 304 PRO F CA  1 
ATOM   13758 C  C   . PRO F 1 304 ? 29.712  23.015  48.837  1.00 27.25  ? 304 PRO F C   1 
ATOM   13759 O  O   . PRO F 1 304 ? 29.754  22.511  47.717  1.00 29.95  ? 304 PRO F O   1 
ATOM   13760 C  CB  . PRO F 1 304 ? 31.191  24.945  49.383  1.00 25.60  ? 304 PRO F CB  1 
ATOM   13761 C  CG  . PRO F 1 304 ? 32.536  25.083  48.870  1.00 26.38  ? 304 PRO F CG  1 
ATOM   13762 C  CD  . PRO F 1 304 ? 33.059  23.737  48.457  1.00 28.12  ? 304 PRO F CD  1 
ATOM   13763 N  N   . ALA F 1 305 ? 28.598  23.328  49.459  1.00 24.80  ? 305 ALA F N   1 
ATOM   13764 C  CA  . ALA F 1 305 ? 27.335  23.304  48.773  1.00 25.17  ? 305 ALA F CA  1 
ATOM   13765 C  C   . ALA F 1 305 ? 27.395  24.160  47.494  1.00 25.53  ? 305 ALA F C   1 
ATOM   13766 O  O   . ALA F 1 305 ? 28.083  25.165  47.401  1.00 25.39  ? 305 ALA F O   1 
ATOM   13767 C  CB  . ALA F 1 305 ? 26.235  23.727  49.753  1.00 25.35  ? 305 ALA F CB  1 
ATOM   13768 N  N   . ALA F 1 306 ? 26.569  23.743  46.521  1.00 28.29  ? 306 ALA F N   1 
ATOM   13769 C  CA  . ALA F 1 306 ? 26.438  24.444  45.266  1.00 26.34  ? 306 ALA F CA  1 
ATOM   13770 C  C   . ALA F 1 306 ? 26.070  25.906  45.476  1.00 28.17  ? 306 ALA F C   1 
ATOM   13771 O  O   . ALA F 1 306 ? 26.643  26.758  44.800  1.00 30.63  ? 306 ALA F O   1 
ATOM   13772 C  CB  . ALA F 1 306 ? 25.464  23.711  44.408  1.00 22.37  ? 306 ALA F CB  1 
ATOM   13773 N  N   . ASP F 1 307 ? 25.168  26.175  46.436  1.00 32.45  ? 307 ASP F N   1 
ATOM   13774 C  CA  . ASP F 1 307 ? 24.613  27.504  46.672  1.00 41.46  ? 307 ASP F CA  1 
ATOM   13775 C  C   . ASP F 1 307 ? 25.698  28.440  47.161  1.00 39.01  ? 307 ASP F C   1 
ATOM   13776 O  O   . ASP F 1 307 ? 25.734  29.617  46.779  1.00 45.80  ? 307 ASP F O   1 
ATOM   13777 C  CB  . ASP F 1 307 ? 23.567  27.593  47.774  1.00 46.96  ? 307 ASP F CB  1 
ATOM   13778 C  CG  . ASP F 1 307 ? 22.646  26.404  47.863  1.00 68.71  ? 307 ASP F CG  1 
ATOM   13779 O  OD1 . ASP F 1 307 ? 21.895  26.168  46.876  1.00 79.81  ? 307 ASP F OD1 1 
ATOM   13780 O  OD2 . ASP F 1 307 ? 22.735  25.705  48.901  1.00 81.73  ? 307 ASP F OD2 1 
ATOM   13781 N  N   . PHE F 1 308 ? 26.590  27.910  48.001  1.00 33.06  ? 308 PHE F N   1 
ATOM   13782 C  CA  . PHE F 1 308 ? 27.670  28.723  48.523  1.00 30.62  ? 308 PHE F CA  1 
ATOM   13783 C  C   . PHE F 1 308 ? 28.435  29.324  47.347  1.00 34.51  ? 308 PHE F C   1 
ATOM   13784 O  O   . PHE F 1 308 ? 28.771  30.515  47.364  1.00 38.93  ? 308 PHE F O   1 
ATOM   13785 C  CB  . PHE F 1 308 ? 28.555  27.864  49.434  1.00 31.46  ? 308 PHE F CB  1 
ATOM   13786 C  CG  . PHE F 1 308 ? 29.728  28.645  50.010  1.00 35.29  ? 308 PHE F CG  1 
ATOM   13787 C  CD1 . PHE F 1 308 ? 29.594  29.280  51.244  1.00 39.19  ? 308 PHE F CD1 1 
ATOM   13788 C  CD2 . PHE F 1 308 ? 30.953  28.734  49.341  1.00 36.30  ? 308 PHE F CD2 1 
ATOM   13789 C  CE1 . PHE F 1 308 ? 30.663  29.949  51.814  1.00 35.18  ? 308 PHE F CE1 1 
ATOM   13790 C  CE2 . PHE F 1 308 ? 32.017  29.417  49.892  1.00 38.45  ? 308 PHE F CE2 1 
ATOM   13791 C  CZ  . PHE F 1 308 ? 31.865  30.031  51.111  1.00 42.05  ? 308 PHE F CZ  1 
ATOM   13792 N  N   . LEU F 1 309 ? 28.744  28.507  46.327  1.00 35.36  ? 309 LEU F N   1 
ATOM   13793 C  CA  . LEU F 1 309 ? 29.569  28.991  45.223  1.00 37.44  ? 309 LEU F CA  1 
ATOM   13794 C  C   . LEU F 1 309 ? 28.813  29.970  44.329  1.00 34.08  ? 309 LEU F C   1 
ATOM   13795 O  O   . LEU F 1 309 ? 29.412  30.918  43.872  1.00 39.78  ? 309 LEU F O   1 
ATOM   13796 C  CB  . LEU F 1 309 ? 30.104  27.815  44.414  1.00 39.48  ? 309 LEU F CB  1 
ATOM   13797 C  CG  . LEU F 1 309 ? 31.029  26.851  45.154  1.00 37.38  ? 309 LEU F CG  1 
ATOM   13798 C  CD1 . LEU F 1 309 ? 31.328  25.735  44.226  1.00 41.12  ? 309 LEU F CD1 1 
ATOM   13799 C  CD2 . LEU F 1 309 ? 32.322  27.417  45.573  1.00 38.87  ? 309 LEU F CD2 1 
ATOM   13800 N  N   . GLU F 1 310 ? 27.521  29.722  44.084  1.00 46.44  ? 310 GLU F N   1 
ATOM   13801 C  CA  . GLU F 1 310 ? 26.667  30.555  43.248  1.00 45.14  ? 310 GLU F CA  1 
ATOM   13802 C  C   . GLU F 1 310 ? 26.715  32.007  43.716  1.00 40.64  ? 310 GLU F C   1 
ATOM   13803 O  O   . GLU F 1 310 ? 26.875  32.872  42.882  1.00 44.84  ? 310 GLU F O   1 
ATOM   13804 C  CB  . GLU F 1 310 ? 25.249  30.002  43.153  1.00 47.66  ? 310 GLU F CB  1 
ATOM   13805 C  CG  . GLU F 1 310 ? 24.424  30.675  42.058  1.00 59.83  ? 310 GLU F CG  1 
ATOM   13806 C  CD  . GLU F 1 310 ? 23.739  29.592  41.265  1.00 69.52  ? 310 GLU F CD  1 
ATOM   13807 O  OE1 . GLU F 1 310 ? 22.898  28.953  41.914  1.00 94.37  ? 310 GLU F OE1 1 
ATOM   13808 O  OE2 . GLU F 1 310 ? 24.082  29.318  40.094  1.00 63.68  ? 310 GLU F OE2 1 
ATOM   13809 N  N   . ASP F 1 311 ? 26.743  32.276  45.024  1.00 50.01  ? 311 ASP F N   1 
ATOM   13810 C  CA  . ASP F 1 311 ? 26.730  33.649  45.577  1.00 53.43  ? 311 ASP F CA  1 
ATOM   13811 C  C   . ASP F 1 311 ? 28.124  34.180  45.904  1.00 56.75  ? 311 ASP F C   1 
ATOM   13812 O  O   . ASP F 1 311 ? 28.411  34.239  47.102  1.00 67.13  ? 311 ASP F O   1 
ATOM   13813 C  CB  . ASP F 1 311 ? 25.927  33.742  46.882  1.00 47.06  ? 311 ASP F CB  1 
ATOM   13814 C  CG  . ASP F 1 311 ? 24.610  32.957  46.840  1.00 67.29  ? 311 ASP F CG  1 
ATOM   13815 O  OD1 . ASP F 1 311 ? 24.139  32.585  45.693  1.00 72.79  ? 311 ASP F OD1 1 
ATOM   13816 O  OD2 . ASP F 1 311 ? 24.097  32.589  47.933  1.00 68.02  ? 311 ASP F OD2 1 
ATOM   13817 N  N   . LEU F 1 312 ? 28.921  34.642  44.910  1.00 61.05  ? 312 LEU F N   1 
ATOM   13818 C  CA  . LEU F 1 312 ? 30.242  35.210  45.217  1.00 80.51  ? 312 LEU F CA  1 
ATOM   13819 C  C   . LEU F 1 312 ? 30.552  36.556  44.481  1.00 72.96  ? 312 LEU F C   1 
ATOM   13820 O  O   . LEU F 1 312 ? 29.891  36.888  43.470  1.00 69.88  ? 312 LEU F O   1 
ATOM   13821 C  CB  . LEU F 1 312 ? 31.381  34.194  45.004  1.00 74.55  ? 312 LEU F CB  1 
ATOM   13822 C  CG  . LEU F 1 312 ? 31.415  32.916  45.856  1.00 61.42  ? 312 LEU F CG  1 
ATOM   13823 C  CD1 . LEU F 1 312 ? 32.699  32.175  45.571  1.00 54.88  ? 312 LEU F CD1 1 
ATOM   13824 C  CD2 . LEU F 1 312 ? 31.345  33.110  47.344  1.00 55.03  ? 312 LEU F CD2 1 
HETATM 13825 C  CHA . HEM G 2 .   ? 16.832  30.873  26.635  1.00 24.91  ? 401 HEM A CHA 1 
HETATM 13826 C  CHB . HEM G 2 .   ? 15.645  29.959  22.068  1.00 21.91  ? 401 HEM A CHB 1 
HETATM 13827 C  CHC . HEM G 2 .   ? 11.193  31.847  22.853  1.00 22.87  ? 401 HEM A CHC 1 
HETATM 13828 C  CHD . HEM G 2 .   ? 12.378  32.284  27.525  1.00 24.47  ? 401 HEM A CHD 1 
HETATM 13829 C  C1A . HEM G 2 .   ? 16.920  30.460  25.300  1.00 26.94  ? 401 HEM A C1A 1 
HETATM 13830 C  C2A . HEM G 2 .   ? 18.103  30.028  24.658  1.00 25.37  ? 401 HEM A C2A 1 
HETATM 13831 C  C3A . HEM G 2 .   ? 17.760  29.733  23.368  1.00 26.13  ? 401 HEM A C3A 1 
HETATM 13832 C  C4A . HEM G 2 .   ? 16.391  30.073  23.168  1.00 23.38  ? 401 HEM A C4A 1 
HETATM 13833 C  CMA . HEM G 2 .   ? 18.702  29.157  22.344  1.00 26.15  ? 401 HEM A CMA 1 
HETATM 13834 C  CAA . HEM G 2 .   ? 19.468  29.853  25.290  1.00 26.97  ? 401 HEM A CAA 1 
HETATM 13835 C  CBA . HEM G 2 .   ? 19.631  28.435  25.915  1.00 28.03  ? 401 HEM A CBA 1 
HETATM 13836 C  CGA . HEM G 2 .   ? 18.736  28.170  27.066  1.00 27.84  ? 401 HEM A CGA 1 
HETATM 13837 O  O1A . HEM G 2 .   ? 17.750  27.456  26.778  1.00 25.69  ? 401 HEM A O1A 1 
HETATM 13838 O  O2A . HEM G 2 .   ? 19.045  28.635  28.232  1.00 28.19  ? 401 HEM A O2A 1 
HETATM 13839 C  C1B . HEM G 2 .   ? 14.313  30.361  21.893  1.00 27.59  ? 401 HEM A C1B 1 
HETATM 13840 C  C2B . HEM G 2 .   ? 13.626  30.306  20.653  1.00 30.74  ? 401 HEM A C2B 1 
HETATM 13841 C  C3B . HEM G 2 .   ? 12.353  30.770  20.856  1.00 30.39  ? 401 HEM A C3B 1 
HETATM 13842 C  C4B . HEM G 2 .   ? 12.294  31.259  22.254  1.00 27.19  ? 401 HEM A C4B 1 
HETATM 13843 C  CMB . HEM G 2 .   ? 14.108  29.658  19.328  1.00 31.83  ? 401 HEM A CMB 1 
HETATM 13844 C  CAB . HEM G 2 .   ? 11.407  30.894  19.718  1.00 29.97  ? 401 HEM A CAB 1 
HETATM 13845 C  CBB . HEM G 2 .   ? 10.917  32.091  19.476  1.00 32.67  ? 401 HEM A CBB 1 
HETATM 13846 C  C1C . HEM G 2 .   ? 11.078  32.164  24.166  1.00 23.31  ? 401 HEM A C1C 1 
HETATM 13847 C  C2C . HEM G 2 .   ? 9.953   32.766  24.852  1.00 27.50  ? 401 HEM A C2C 1 
HETATM 13848 C  C3C . HEM G 2 .   ? 10.337  32.948  26.199  1.00 24.76  ? 401 HEM A C3C 1 
HETATM 13849 C  C4C . HEM G 2 .   ? 11.664  32.410  26.312  1.00 24.37  ? 401 HEM A C4C 1 
HETATM 13850 C  CMC . HEM G 2 .   ? 8.634   33.165  24.251  1.00 28.28  ? 401 HEM A CMC 1 
HETATM 13851 C  CAC . HEM G 2 .   ? 9.675   33.450  27.423  1.00 25.67  ? 401 HEM A CAC 1 
HETATM 13852 C  CBC . HEM G 2 .   ? 8.454   33.877  27.495  1.00 27.51  ? 401 HEM A CBC 1 
HETATM 13853 C  C1D . HEM G 2 .   ? 13.663  31.869  27.696  1.00 23.09  ? 401 HEM A C1D 1 
HETATM 13854 C  C2D . HEM G 2 .   ? 14.287  31.928  28.975  1.00 25.66  ? 401 HEM A C2D 1 
HETATM 13855 C  C3D . HEM G 2 .   ? 15.590  31.570  28.744  1.00 27.24  ? 401 HEM A C3D 1 
HETATM 13856 C  C4D . HEM G 2 .   ? 15.649  31.323  27.261  1.00 27.19  ? 401 HEM A C4D 1 
HETATM 13857 C  CMD . HEM G 2 .   ? 13.653  32.256  30.314  1.00 28.53  ? 401 HEM A CMD 1 
HETATM 13858 C  CAD . HEM G 2 .   ? 16.757  31.355  29.743  1.00 22.31  ? 401 HEM A CAD 1 
HETATM 13859 C  CBD . HEM G 2 .   ? 17.495  32.742  30.067  1.00 26.95  ? 401 HEM A CBD 1 
HETATM 13860 C  CGD . HEM G 2 .   ? 18.606  32.704  31.166  1.00 25.48  ? 401 HEM A CGD 1 
HETATM 13861 O  O1D . HEM G 2 .   ? 18.484  32.970  32.372  1.00 33.49  ? 401 HEM A O1D 1 
HETATM 13862 O  O2D . HEM G 2 .   ? 19.734  32.327  30.855  1.00 25.92  ? 401 HEM A O2D 1 
HETATM 13863 N  NA  . HEM G 2 .   ? 15.887  30.517  24.350  1.00 28.34  ? 401 HEM A NA  1 
HETATM 13864 N  NB  . HEM G 2 .   ? 13.494  30.932  22.788  1.00 32.18  ? 401 HEM A NB  1 
HETATM 13865 N  NC  . HEM G 2 .   ? 12.055  31.930  25.071  1.00 23.33  ? 401 HEM A NC  1 
HETATM 13866 N  ND  . HEM G 2 .   ? 14.477  31.543  26.698  1.00 23.66  ? 401 HEM A ND  1 
HETATM 13867 FE FE  . HEM G 2 .   ? 14.079  31.354  24.800  1.00 22.73  ? 401 HEM A FE  1 
HETATM 13868 MG MG  . MG  H 3 .   ? 12.351  31.961  2.994   1.00 24.30  ? 402 MG  A MG  1 
HETATM 13869 O  O   . O   I 4 .   ? 13.332  29.650  24.964  0.65 21.26  ? 403 O   A O   1 
HETATM 13870 C  CHA . HEM J 2 .   ? 39.099  -23.818 24.048  1.00 23.02  ? 501 HEM B CHA 1 
HETATM 13871 C  CHB . HEM J 2 .   ? 36.111  -24.768 27.696  1.00 23.38  ? 501 HEM B CHB 1 
HETATM 13872 C  CHC . HEM J 2 .   ? 34.728  -29.001 25.851  1.00 26.27  ? 501 HEM B CHC 1 
HETATM 13873 C  CHD . HEM J 2 .   ? 37.334  -27.789 21.942  1.00 21.37  ? 501 HEM B CHD 1 
HETATM 13874 C  C1A . HEM J 2 .   ? 38.390  -23.834 25.267  1.00 23.61  ? 501 HEM B C1A 1 
HETATM 13875 C  C2A . HEM J 2 .   ? 38.589  -22.770 26.226  1.00 22.92  ? 501 HEM B C2A 1 
HETATM 13876 C  C3A . HEM J 2 .   ? 37.718  -23.031 27.244  1.00 21.62  ? 501 HEM B C3A 1 
HETATM 13877 C  C4A . HEM J 2 .   ? 37.035  -24.226 26.878  1.00 22.33  ? 501 HEM B C4A 1 
HETATM 13878 C  CMA . HEM J 2 .   ? 37.511  -22.200 28.496  1.00 19.95  ? 501 HEM B CMA 1 
HETATM 13879 C  CAA . HEM J 2 .   ? 39.539  -21.580 26.123  1.00 21.11  ? 501 HEM B CAA 1 
HETATM 13880 C  CBA . HEM J 2 .   ? 38.962  -20.295 25.516  1.00 22.95  ? 501 HEM B CBA 1 
HETATM 13881 C  CGA . HEM J 2 .   ? 38.533  -20.564 24.045  1.00 26.77  ? 501 HEM B CGA 1 
HETATM 13882 O  O1A . HEM J 2 .   ? 37.340  -20.896 23.741  1.00 25.35  ? 501 HEM B O1A 1 
HETATM 13883 O  O2A . HEM J 2 .   ? 39.364  -20.468 23.069  1.00 27.58  ? 501 HEM B O2A 1 
HETATM 13884 C  C1B . HEM J 2 .   ? 35.505  -25.974 27.501  1.00 21.91  ? 501 HEM B C1B 1 
HETATM 13885 C  C2B . HEM J 2 .   ? 34.583  -26.511 28.447  1.00 22.17  ? 501 HEM B C2B 1 
HETATM 13886 C  C3B . HEM J 2 .   ? 34.174  -27.706 27.975  1.00 24.62  ? 501 HEM B C3B 1 
HETATM 13887 C  C4B . HEM J 2 .   ? 34.858  -27.895 26.687  1.00 24.60  ? 501 HEM B C4B 1 
HETATM 13888 C  CMB . HEM J 2 .   ? 34.169  -25.939 29.749  1.00 22.52  ? 501 HEM B CMB 1 
HETATM 13889 C  CAB . HEM J 2 .   ? 33.356  -28.557 28.807  1.00 30.14  ? 501 HEM B CAB 1 
HETATM 13890 C  CBB . HEM J 2 .   ? 33.736  -29.756 28.905  1.00 36.56  ? 501 HEM B CBB 1 
HETATM 13891 C  C1C . HEM J 2 .   ? 35.334  -29.039 24.606  1.00 23.26  ? 501 HEM B C1C 1 
HETATM 13892 C  C2C . HEM J 2 .   ? 35.223  -30.117 23.692  1.00 23.11  ? 501 HEM B C2C 1 
HETATM 13893 C  C3C . HEM J 2 .   ? 35.980  -29.799 22.566  1.00 23.18  ? 501 HEM B C3C 1 
HETATM 13894 C  C4C . HEM J 2 .   ? 36.567  -28.520 22.880  1.00 21.00  ? 501 HEM B C4C 1 
HETATM 13895 C  CMC . HEM J 2 .   ? 34.430  -31.331 23.977  1.00 23.18  ? 501 HEM B CMC 1 
HETATM 13896 C  CAC . HEM J 2 .   ? 36.165  -30.516 21.258  1.00 25.45  ? 501 HEM B CAC 1 
HETATM 13897 C  CBC . HEM J 2 .   ? 35.587  -31.651 20.909  1.00 27.76  ? 501 HEM B CBC 1 
HETATM 13898 C  C1D . HEM J 2 .   ? 38.016  -26.576 22.200  1.00 21.51  ? 501 HEM B C1D 1 
HETATM 13899 C  C2D . HEM J 2 .   ? 38.841  -25.938 21.198  1.00 22.66  ? 501 HEM B C2D 1 
HETATM 13900 C  C3D . HEM J 2 .   ? 39.404  -24.839 21.754  1.00 22.59  ? 501 HEM B C3D 1 
HETATM 13901 C  C4D . HEM J 2 .   ? 38.797  -24.803 23.100  1.00 20.85  ? 501 HEM B C4D 1 
HETATM 13902 C  CMD . HEM J 2 .   ? 39.070  -26.479 19.792  1.00 21.63  ? 501 HEM B CMD 1 
HETATM 13903 C  CAD . HEM J 2 .   ? 40.528  -23.896 21.107  1.00 27.50  ? 501 HEM B CAD 1 
HETATM 13904 C  CBD . HEM J 2 .   ? 41.949  -24.407 20.542  1.00 30.37  ? 501 HEM B CBD 1 
HETATM 13905 C  CGD . HEM J 2 .   ? 42.940  -23.285 20.193  1.00 31.21  ? 501 HEM B CGD 1 
HETATM 13906 O  O1D . HEM J 2 .   ? 43.104  -22.616 21.294  1.00 26.92  ? 501 HEM B O1D 1 
HETATM 13907 O  O2D . HEM J 2 .   ? 43.622  -22.965 19.080  1.00 50.12  ? 501 HEM B O2D 1 
HETATM 13908 N  NA  . HEM J 2 .   ? 37.422  -24.718 25.717  1.00 20.18  ? 501 HEM B NA  1 
HETATM 13909 N  NB  . HEM J 2 .   ? 35.659  -26.782 26.477  1.00 23.71  ? 501 HEM B NB  1 
HETATM 13910 N  NC  . HEM J 2 .   ? 36.154  -28.092 24.120  1.00 19.44  ? 501 HEM B NC  1 
HETATM 13911 N  ND  . HEM J 2 .   ? 37.965  -25.871 23.349  1.00 23.09  ? 501 HEM B ND  1 
HETATM 13912 FE FE  . HEM J 2 .   ? 36.872  -26.385 24.880  1.00 23.22  ? 501 HEM B FE  1 
HETATM 13913 C  CHA . HEM K 2 .   ? 2.932   -8.691  3.257   1.00 29.05  ? 401 HEM C CHA 1 
HETATM 13914 C  CHB . HEM K 2 .   ? 0.743   -4.863  5.054   1.00 29.21  ? 401 HEM C CHB 1 
HETATM 13915 C  CHC . HEM K 2 .   ? 0.434   -2.904  0.562   1.00 24.80  ? 401 HEM C CHC 1 
HETATM 13916 C  CHD . HEM K 2 .   ? 3.200   -6.639  -1.064  1.00 25.86  ? 401 HEM C CHD 1 
HETATM 13917 C  C1A . HEM K 2 .   ? 2.300   -7.807  4.129   1.00 29.23  ? 401 HEM C C1A 1 
HETATM 13918 C  C2A . HEM K 2 .   ? 1.974   -8.074  5.496   1.00 29.14  ? 401 HEM C C2A 1 
HETATM 13919 C  C3A . HEM K 2 .   ? 1.374   -6.996  5.964   1.00 31.05  ? 401 HEM C C3A 1 
HETATM 13920 C  C4A . HEM K 2 .   ? 1.348   -6.060  4.932   1.00 32.25  ? 401 HEM C C4A 1 
HETATM 13921 C  CMA . HEM K 2 .   ? 0.830   -6.753  7.330   1.00 32.04  ? 401 HEM C CMA 1 
HETATM 13922 C  CAA . HEM K 2 .   ? 2.234   -9.337  6.277   1.00 31.80  ? 401 HEM C CAA 1 
HETATM 13923 C  CBA . HEM K 2 .   ? 3.719   -9.538  6.751   1.00 29.27  ? 401 HEM C CBA 1 
HETATM 13924 C  CGA . HEM K 2 .   ? 4.882   -9.186  5.852   1.00 28.16  ? 401 HEM C CGA 1 
HETATM 13925 O  O1A . HEM K 2 .   ? 5.460   -10.164 5.310   1.00 28.87  ? 401 HEM C O1A 1 
HETATM 13926 O  O2A . HEM K 2 .   ? 5.251   -7.991  5.616   1.00 24.45  ? 401 HEM C O2A 1 
HETATM 13927 C  C1B . HEM K 2 .   ? 0.476   -4.048  3.955   1.00 31.80  ? 401 HEM C C1B 1 
HETATM 13928 C  C2B . HEM K 2 .   ? -0.278  -2.802  4.092   1.00 28.08  ? 401 HEM C C2B 1 
HETATM 13929 C  C3B . HEM K 2 .   ? -0.280  -2.287  2.818   1.00 29.18  ? 401 HEM C C3B 1 
HETATM 13930 C  C4B . HEM K 2 .   ? 0.383   -3.206  1.924   1.00 29.19  ? 401 HEM C C4B 1 
HETATM 13931 C  CMB . HEM K 2 .   ? -0.819  -2.125  5.360   1.00 25.36  ? 401 HEM C CMB 1 
HETATM 13932 C  CAB . HEM K 2 .   ? -0.946  -1.145  2.197   1.00 32.46  ? 401 HEM C CAB 1 
HETATM 13933 C  CBB . HEM K 2 .   ? -2.107  -0.927  2.685   1.00 36.86  ? 401 HEM C CBB 1 
HETATM 13934 C  C1C . HEM K 2 .   ? 1.121   -3.702  -0.314  1.00 27.65  ? 401 HEM C C1C 1 
HETATM 13935 C  C2C . HEM K 2 .   ? 1.313   -3.450  -1.708  1.00 27.57  ? 401 HEM C C2C 1 
HETATM 13936 C  C3C . HEM K 2 .   ? 2.108   -4.552  -2.140  1.00 26.39  ? 401 HEM C C3C 1 
HETATM 13937 C  C4C . HEM K 2 .   ? 2.339   -5.462  -0.979  1.00 26.34  ? 401 HEM C C4C 1 
HETATM 13938 C  CMC . HEM K 2 .   ? 0.782   -2.230  -2.474  1.00 30.35  ? 401 HEM C CMC 1 
HETATM 13939 C  CAC . HEM K 2 .   ? 2.725   -4.966  -3.432  1.00 23.42  ? 401 HEM C CAC 1 
HETATM 13940 C  CBC . HEM K 2 .   ? 2.494   -4.357  -4.512  1.00 26.12  ? 401 HEM C CBC 1 
HETATM 13941 C  C1D . HEM K 2 .   ? 3.457   -7.498  -0.038  1.00 23.96  ? 401 HEM C C1D 1 
HETATM 13942 C  C2D . HEM K 2 .   ? 4.189   -8.746  -0.173  1.00 22.86  ? 401 HEM C C2D 1 
HETATM 13943 C  C3D . HEM K 2 .   ? 4.101   -9.330  1.007   1.00 23.15  ? 401 HEM C C3D 1 
HETATM 13944 C  C4D . HEM K 2 .   ? 3.231   -8.433  1.844   1.00 27.97  ? 401 HEM C C4D 1 
HETATM 13945 C  CMD . HEM K 2 .   ? 4.899   -9.262  -1.386  1.00 29.06  ? 401 HEM C CMD 1 
HETATM 13946 C  CAD . HEM K 2 .   ? 4.642   -10.668 1.488   1.00 28.31  ? 401 HEM C CAD 1 
HETATM 13947 C  CBD . HEM K 2 .   ? 3.906   -11.958 0.952   1.00 31.98  ? 401 HEM C CBD 1 
HETATM 13948 C  CGD . HEM K 2 .   ? 4.607   -13.316 1.347   1.00 35.42  ? 401 HEM C CGD 1 
HETATM 13949 O  O1D . HEM K 2 .   ? 4.320   -13.629 2.527   1.00 31.74  ? 401 HEM C O1D 1 
HETATM 13950 O  O2D . HEM K 2 .   ? 5.421   -14.100 0.640   1.00 40.05  ? 401 HEM C O2D 1 
HETATM 13951 N  NA  . HEM K 2 .   ? 1.882   -6.557  3.779   1.00 30.18  ? 401 HEM C NA  1 
HETATM 13952 N  NB  . HEM K 2 .   ? 0.836   -4.214  2.681   1.00 28.11  ? 401 HEM C NB  1 
HETATM 13953 N  NC  . HEM K 2 .   ? 1.736   -4.864  0.085   1.00 23.73  ? 401 HEM C NC  1 
HETATM 13954 N  ND  . HEM K 2 .   ? 2.849   -7.303  1.152   1.00 26.61  ? 401 HEM C ND  1 
HETATM 13955 FE FE  . HEM K 2 .   ? 1.771   -5.823  1.869   1.00 27.51  ? 401 HEM C FE  1 
HETATM 13956 C  CHA . HEM L 2 .   ? 40.190  16.568  5.334   1.00 20.85  ? 401 HEM D CHA 1 
HETATM 13957 C  CHB . HEM L 2 .   ? 41.583  18.115  9.665   1.00 21.63  ? 401 HEM D CHB 1 
HETATM 13958 C  CHC . HEM L 2 .   ? 46.144  16.830  8.641   1.00 20.06  ? 401 HEM D CHC 1 
HETATM 13959 C  CHD . HEM L 2 .   ? 44.517  14.820  4.628   1.00 18.62  ? 401 HEM D CHD 1 
HETATM 13960 C  C1A . HEM L 2 .   ? 40.190  17.106  6.613   1.00 20.00  ? 401 HEM D C1A 1 
HETATM 13961 C  C2A . HEM L 2 .   ? 39.006  17.691  7.212   1.00 19.00  ? 401 HEM D C2A 1 
HETATM 13962 C  C3A . HEM L 2 .   ? 39.413  18.121  8.433   1.00 18.31  ? 401 HEM D C3A 1 
HETATM 13963 C  C4A . HEM L 2 .   ? 40.824  17.778  8.585   1.00 19.91  ? 401 HEM D C4A 1 
HETATM 13964 C  CMA . HEM L 2 .   ? 38.619  18.911  9.453   1.00 17.76  ? 401 HEM D CMA 1 
HETATM 13965 C  CAA . HEM L 2 .   ? 37.633  17.905  6.573   1.00 18.87  ? 401 HEM D CAA 1 
HETATM 13966 C  CBA . HEM L 2 .   ? 36.738  16.735  6.885   1.00 19.01  ? 401 HEM D CBA 1 
HETATM 13967 C  CGA . HEM L 2 .   ? 37.219  15.383  6.366   1.00 21.06  ? 401 HEM D CGA 1 
HETATM 13968 O  O1A . HEM L 2 .   ? 36.943  14.956  5.160   1.00 23.18  ? 401 HEM D O1A 1 
HETATM 13969 O  O2A . HEM L 2 .   ? 37.880  14.685  7.240   1.00 24.23  ? 401 HEM D O2A 1 
HETATM 13970 C  C1B . HEM L 2 .   ? 42.958  17.941  9.766   1.00 24.84  ? 401 HEM D C1B 1 
HETATM 13971 C  C2B . HEM L 2 .   ? 43.766  18.334  10.911  1.00 22.06  ? 401 HEM D C2B 1 
HETATM 13972 C  C3B . HEM L 2 .   ? 45.026  17.892  10.583  1.00 25.53  ? 401 HEM D C3B 1 
HETATM 13973 C  C4B . HEM L 2 .   ? 45.009  17.310  9.245   1.00 24.01  ? 401 HEM D C4B 1 
HETATM 13974 C  CMB . HEM L 2 .   ? 43.301  18.949  12.254  1.00 22.50  ? 401 HEM D CMB 1 
HETATM 13975 C  CAB . HEM L 2 .   ? 46.387  18.030  11.097  1.00 28.89  ? 401 HEM D CAB 1 
HETATM 13976 C  CBB . HEM L 2 .   ? 46.661  19.078  11.777  1.00 30.95  ? 401 HEM D CBB 1 
HETATM 13977 C  C1C . HEM L 2 .   ? 46.135  16.202  7.398   1.00 20.72  ? 401 HEM D C1C 1 
HETATM 13978 C  C2C . HEM L 2 .   ? 47.262  15.731  6.720   1.00 20.46  ? 401 HEM D C2C 1 
HETATM 13979 C  C3C . HEM L 2 .   ? 46.830  15.166  5.573   1.00 18.80  ? 401 HEM D C3C 1 
HETATM 13980 C  C4C . HEM L 2 .   ? 45.392  15.273  5.588   1.00 18.63  ? 401 HEM D C4C 1 
HETATM 13981 C  CMC . HEM L 2 .   ? 48.602  15.912  7.350   1.00 21.42  ? 401 HEM D CMC 1 
HETATM 13982 C  CAC . HEM L 2 .   ? 47.543  14.474  4.490   1.00 21.95  ? 401 HEM D CAC 1 
HETATM 13983 C  CBC . HEM L 2 .   ? 48.756  14.049  4.561   1.00 24.59  ? 401 HEM D CBC 1 
HETATM 13984 C  C1D . HEM L 2 .   ? 43.157  15.085  4.492   1.00 18.18  ? 401 HEM D C1D 1 
HETATM 13985 C  C2D . HEM L 2 .   ? 42.384  14.608  3.298   1.00 18.90  ? 401 HEM D C2D 1 
HETATM 13986 C  C3D . HEM L 2 .   ? 41.140  15.181  3.422   1.00 17.40  ? 401 HEM D C3D 1 
HETATM 13987 C  C4D . HEM L 2 .   ? 41.257  15.915  4.748   1.00 18.02  ? 401 HEM D C4D 1 
HETATM 13988 C  CMD . HEM L 2 .   ? 42.956  13.701  2.198   1.00 19.37  ? 401 HEM D CMD 1 
HETATM 13989 C  CAD . HEM L 2 .   ? 39.970  15.079  2.540   1.00 15.91  ? 401 HEM D CAD 1 
HETATM 13990 C  CBD . HEM L 2 .   ? 39.931  15.785  1.161   1.00 19.05  ? 401 HEM D CBD 1 
HETATM 13991 C  CGD . HEM L 2 .   ? 38.751  15.518  0.136   1.00 20.47  ? 401 HEM D CGD 1 
HETATM 13992 O  O1D . HEM L 2 .   ? 38.002  16.311  0.831   1.00 21.04  ? 401 HEM D O1D 1 
HETATM 13993 O  O2D . HEM L 2 .   ? 38.245  14.832  -1.033  1.00 37.41  ? 401 HEM D O2D 1 
HETATM 13994 N  NA  . HEM L 2 .   ? 41.306  17.181  7.479   1.00 21.41  ? 401 HEM D NA  1 
HETATM 13995 N  NB  . HEM L 2 .   ? 43.744  17.378  8.809   1.00 24.76  ? 401 HEM D NB  1 
HETATM 13996 N  NC  . HEM L 2 .   ? 45.013  15.913  6.702   1.00 20.04  ? 401 HEM D NC  1 
HETATM 13997 N  ND  . HEM L 2 .   ? 42.478  15.862  5.342   1.00 19.47  ? 401 HEM D ND  1 
HETATM 13998 FE FE  . HEM L 2 .   ? 43.156  16.666  7.006   1.00 19.70  ? 401 HEM D FE  1 
HETATM 13999 MG MG  . MG  M 3 .   ? 52.175  33.522  6.702   1.00 47.25  ? 402 MG  D MG  1 
HETATM 14000 O  O1  . PG4 N 5 .   ? 70.076  -11.283 8.850   1.00 51.07  ? 403 PG4 D O1  1 
HETATM 14001 C  C1  . PG4 N 5 .   ? 68.830  -10.609 8.447   1.00 46.53  ? 403 PG4 D C1  1 
HETATM 14002 C  C2  . PG4 N 5 .   ? 67.585  -11.088 9.193   1.00 49.68  ? 403 PG4 D C2  1 
HETATM 14003 O  O2  . PG4 N 5 .   ? 67.665  -12.431 9.723   1.00 62.33  ? 403 PG4 D O2  1 
HETATM 14004 C  C3  . PG4 N 5 .   ? 66.792  -12.726 10.841  1.00 56.28  ? 403 PG4 D C3  1 
HETATM 14005 C  C4  . PG4 N 5 .   ? 65.783  -13.865 10.499  1.00 62.85  ? 403 PG4 D C4  1 
HETATM 14006 O  O3  . PG4 N 5 .   ? 65.533  -14.040 9.083   1.00 63.21  ? 403 PG4 D O3  1 
HETATM 14007 C  C5  . PG4 N 5 .   ? 64.277  -13.626 8.530   1.00 59.18  ? 403 PG4 D C5  1 
HETATM 14008 C  C6  . PG4 N 5 .   ? 63.368  -14.832 8.235   1.00 66.30  ? 403 PG4 D C6  1 
HETATM 14009 O  O4  . PG4 N 5 .   ? 61.982  -14.447 8.261   1.00 79.26  ? 403 PG4 D O4  1 
HETATM 14010 C  C7  . PG4 N 5 .   ? 61.528  -13.823 7.045   1.00 85.97  ? 403 PG4 D C7  1 
HETATM 14011 C  C8  . PG4 N 5 .   ? 60.053  -13.358 7.091   1.00 83.73  ? 403 PG4 D C8  1 
HETATM 14012 O  O5  . PG4 N 5 .   ? 59.174  -14.095 8.008   1.00 84.09  ? 403 PG4 D O5  1 
HETATM 14013 O  O   . O   O 4 .   ? 42.749  14.916  8.069   0.55 22.44  ? 404 O   D O   1 
HETATM 14014 C  CHA . HEM P 2 .   ? -3.970  -7.519  37.174  1.00 24.76  ? 401 HEM E CHA 1 
HETATM 14015 C  CHB . HEM P 2 .   ? -2.445  -11.618 35.225  1.00 27.38  ? 401 HEM E CHB 1 
HETATM 14016 C  CHC . HEM P 2 .   ? -2.779  -13.958 39.438  1.00 25.73  ? 401 HEM E CHC 1 
HETATM 14017 C  CHD . HEM P 2 .   ? -3.801  -9.623  41.449  1.00 22.33  ? 401 HEM E CHD 1 
HETATM 14018 C  C1A . HEM P 2 .   ? -3.560  -8.419  36.310  1.00 23.60  ? 401 HEM E C1A 1 
HETATM 14019 C  C2A . HEM P 2 .   ? -3.540  -8.161  34.907  1.00 23.52  ? 401 HEM E C2A 1 
HETATM 14020 C  C3A . HEM P 2 .   ? -3.136  -9.346  34.350  1.00 25.18  ? 401 HEM E C3A 1 
HETATM 14021 C  C4A . HEM P 2 .   ? -2.924  -10.322 35.387  1.00 25.80  ? 401 HEM E C4A 1 
HETATM 14022 C  CMA . HEM P 2 .   ? -2.876  -9.611  32.881  1.00 24.32  ? 401 HEM E CMA 1 
HETATM 14023 C  CAA . HEM P 2 .   ? -3.915  -6.915  34.170  1.00 24.24  ? 401 HEM E CAA 1 
HETATM 14024 C  CBA . HEM P 2 .   ? -2.714  -6.001  33.926  1.00 27.18  ? 401 HEM E CBA 1 
HETATM 14025 C  CGA . HEM P 2 .   ? -2.087  -5.522  35.212  1.00 27.02  ? 401 HEM E CGA 1 
HETATM 14026 O  O1A . HEM P 2 .   ? -2.632  -4.499  35.775  1.00 26.30  ? 401 HEM E O1A 1 
HETATM 14027 O  O2A . HEM P 2 .   ? -1.080  -6.253  35.616  1.00 24.22  ? 401 HEM E O2A 1 
HETATM 14028 C  C1B . HEM P 2 .   ? -2.370  -12.597 36.199  1.00 26.74  ? 401 HEM E C1B 1 
HETATM 14029 C  C2B . HEM P 2 .   ? -1.935  -13.933 35.892  1.00 23.82  ? 401 HEM E C2B 1 
HETATM 14030 C  C3B . HEM P 2 .   ? -2.026  -14.597 37.087  1.00 26.98  ? 401 HEM E C3B 1 
HETATM 14031 C  C4B . HEM P 2 .   ? -2.559  -13.635 38.129  1.00 28.50  ? 401 HEM E C4B 1 
HETATM 14032 C  CMB . HEM P 2 .   ? -1.456  -14.622 34.623  1.00 23.74  ? 401 HEM E CMB 1 
HETATM 14033 C  CAB . HEM P 2 .   ? -1.863  -16.057 37.075  1.00 29.81  ? 401 HEM E CAB 1 
HETATM 14034 C  CBB . HEM P 2 .   ? -2.810  -16.888 37.494  1.00 31.27  ? 401 HEM E CBB 1 
HETATM 14035 C  C1C . HEM P 2 .   ? -3.130  -12.970 40.379  1.00 25.35  ? 401 HEM E C1C 1 
HETATM 14036 C  C2C . HEM P 2 .   ? -3.332  -13.199 41.765  1.00 23.72  ? 401 HEM E C2C 1 
HETATM 14037 C  C3C . HEM P 2 .   ? -3.625  -11.907 42.316  1.00 24.68  ? 401 HEM E C3C 1 
HETATM 14038 C  C4C . HEM P 2 .   ? -3.606  -10.951 41.267  1.00 20.75  ? 401 HEM E C4C 1 
HETATM 14039 C  CMC . HEM P 2 .   ? -3.220  -14.591 42.396  1.00 27.16  ? 401 HEM E CMC 1 
HETATM 14040 C  CAC . HEM P 2 .   ? -3.889  -11.496 43.738  1.00 27.51  ? 401 HEM E CAC 1 
HETATM 14041 C  CBC . HEM P 2 .   ? -3.661  -12.392 44.641  1.00 29.24  ? 401 HEM E CBC 1 
HETATM 14042 C  C1D . HEM P 2 .   ? -3.922  -8.742  40.392  1.00 22.95  ? 401 HEM E C1D 1 
HETATM 14043 C  C2D . HEM P 2 .   ? -4.187  -7.339  40.615  1.00 22.37  ? 401 HEM E C2D 1 
HETATM 14044 C  C3D . HEM P 2 .   ? -4.309  -6.715  39.451  1.00 23.09  ? 401 HEM E C3D 1 
HETATM 14045 C  C4D . HEM P 2 .   ? -4.017  -7.817  38.511  1.00 25.61  ? 401 HEM E C4D 1 
HETATM 14046 C  CMD . HEM P 2 .   ? -4.413  -6.742  41.953  1.00 25.78  ? 401 HEM E CMD 1 
HETATM 14047 C  CAD . HEM P 2 .   ? -4.680  -5.231  39.156  1.00 27.15  ? 401 HEM E CAD 1 
HETATM 14048 C  CBD . HEM P 2 .   ? -6.122  -4.708  39.587  1.00 31.25  ? 401 HEM E CBD 1 
HETATM 14049 C  CGD . HEM P 2 .   ? -6.479  -3.252  39.261  1.00 30.34  ? 401 HEM E CGD 1 
HETATM 14050 O  O1D . HEM P 2 .   ? -6.736  -2.133  39.963  1.00 39.82  ? 401 HEM E O1D 1 
HETATM 14051 O  O2D . HEM P 2 .   ? -6.557  -3.232  38.012  1.00 23.85  ? 401 HEM E O2D 1 
HETATM 14052 N  NA  . HEM P 2 .   ? -3.204  -9.732  36.581  1.00 24.76  ? 401 HEM E NA  1 
HETATM 14053 N  NB  . HEM P 2 .   ? -2.759  -12.474 37.500  1.00 25.00  ? 401 HEM E NB  1 
HETATM 14054 N  NC  . HEM P 2 .   ? -3.285  -11.612 40.148  1.00 24.77  ? 401 HEM E NC  1 
HETATM 14055 N  ND  . HEM P 2 .   ? -3.815  -9.019  39.099  1.00 23.98  ? 401 HEM E ND  1 
HETATM 14056 FE FE  . HEM P 2 .   ? -3.345  -10.699 38.296  1.00 26.47  ? 401 HEM E FE  1 
HETATM 14057 C  CHA . HEM Q 2 .   ? 37.977  -1.248  49.875  1.00 23.65  ? 401 HEM F CHA 1 
HETATM 14058 C  CHB . HEM Q 2 .   ? 41.531  -0.816  46.603  1.00 27.30  ? 401 HEM F CHB 1 
HETATM 14059 C  CHC . HEM Q 2 .   ? 43.197  3.035   49.065  1.00 23.04  ? 401 HEM F CHC 1 
HETATM 14060 C  CHD . HEM Q 2 .   ? 39.473  2.800   51.872  1.00 20.99  ? 401 HEM F CHD 1 
HETATM 14061 C  C1A . HEM Q 2 .   ? 38.767  -1.439  48.787  1.00 24.11  ? 401 HEM F C1A 1 
HETATM 14062 C  C2A . HEM Q 2 .   ? 38.655  -2.604  47.931  1.00 23.57  ? 401 HEM F C2A 1 
HETATM 14063 C  C3A . HEM Q 2 .   ? 39.708  -2.474  47.036  1.00 23.32  ? 401 HEM F C3A 1 
HETATM 14064 C  C4A . HEM Q 2 .   ? 40.407  -1.233  47.321  1.00 27.97  ? 401 HEM F C4A 1 
HETATM 14065 C  CMA . HEM Q 2 .   ? 40.177  -3.346  45.908  1.00 23.32  ? 401 HEM F CMA 1 
HETATM 14066 C  CAA . HEM Q 2 .   ? 37.684  -3.765  48.082  1.00 21.53  ? 401 HEM F CAA 1 
HETATM 14067 C  CBA . HEM Q 2 .   ? 36.455  -3.490  47.264  1.00 22.88  ? 401 HEM F CBA 1 
HETATM 14068 C  CGA . HEM Q 2 .   ? 35.650  -2.352  47.757  1.00 22.76  ? 401 HEM F CGA 1 
HETATM 14069 O  O1A . HEM Q 2 .   ? 35.724  -1.303  47.107  1.00 23.06  ? 401 HEM F O1A 1 
HETATM 14070 O  O2A . HEM Q 2 .   ? 34.873  -2.444  48.747  1.00 22.49  ? 401 HEM F O2A 1 
HETATM 14071 C  C1B . HEM Q 2 .   ? 42.308  0.266   46.970  1.00 28.46  ? 401 HEM F C1B 1 
HETATM 14072 C  C2B . HEM Q 2 .   ? 43.511  0.711   46.305  1.00 25.73  ? 401 HEM F C2B 1 
HETATM 14073 C  C3B . HEM Q 2 .   ? 43.954  1.779   46.978  1.00 29.03  ? 401 HEM F C3B 1 
HETATM 14074 C  C4B . HEM Q 2 .   ? 43.031  1.989   48.135  1.00 27.55  ? 401 HEM F C4B 1 
HETATM 14075 C  CMB . HEM Q 2 .   ? 44.149  0.127   45.117  1.00 30.69  ? 401 HEM F CMB 1 
HETATM 14076 C  CAB . HEM Q 2 .   ? 45.147  2.639   46.950  1.00 36.07  ? 401 HEM F CAB 1 
HETATM 14077 C  CBB . HEM Q 2 .   ? 46.280  2.213   46.567  1.00 41.44  ? 401 HEM F CBB 1 
HETATM 14078 C  C1C . HEM Q 2 .   ? 42.338  3.323   50.071  1.00 21.79  ? 401 HEM F C1C 1 
HETATM 14079 C  C2C . HEM Q 2 .   ? 42.531  4.340   51.017  1.00 23.38  ? 401 HEM F C2C 1 
HETATM 14080 C  C3C . HEM Q 2 .   ? 41.470  4.317   51.833  1.00 21.67  ? 401 HEM F C3C 1 
HETATM 14081 C  C4C . HEM Q 2 .   ? 40.645  3.190   51.354  1.00 21.35  ? 401 HEM F C4C 1 
HETATM 14082 C  CMC . HEM Q 2 .   ? 43.713  5.270   51.051  1.00 23.31  ? 401 HEM F CMC 1 
HETATM 14083 C  CAC . HEM Q 2 .   ? 41.188  5.206   53.004  1.00 26.57  ? 401 HEM F CAC 1 
HETATM 14084 C  CBC . HEM Q 2 .   ? 41.685  6.407   53.269  1.00 29.12  ? 401 HEM F CBC 1 
HETATM 14085 C  C1D . HEM Q 2 .   ? 38.804  1.711   51.580  1.00 22.60  ? 401 HEM F C1D 1 
HETATM 14086 C  C2D . HEM Q 2 .   ? 37.544  1.402   52.285  1.00 23.14  ? 401 HEM F C2D 1 
HETATM 14087 C  C3D . HEM Q 2 .   ? 37.130  0.250   51.738  1.00 25.12  ? 401 HEM F C3D 1 
HETATM 14088 C  C4D . HEM Q 2 .   ? 38.166  -0.135  50.689  1.00 24.48  ? 401 HEM F C4D 1 
HETATM 14089 C  CMD . HEM Q 2 .   ? 36.804  2.147   53.353  1.00 25.62  ? 401 HEM F CMD 1 
HETATM 14090 C  CAD . HEM Q 2 .   ? 35.907  -0.567  52.116  1.00 24.50  ? 401 HEM F CAD 1 
HETATM 14091 C  CBD . HEM Q 2 .   ? 36.118  -1.549  53.331  1.00 26.79  ? 401 HEM F CBD 1 
HETATM 14092 C  CGD . HEM Q 2 .   ? 34.779  -2.209  53.787  1.00 27.48  ? 401 HEM F CGD 1 
HETATM 14093 O  O1D . HEM Q 2 .   ? 34.684  -3.305  53.135  1.00 27.10  ? 401 HEM F O1D 1 
HETATM 14094 O  O2D . HEM Q 2 .   ? 33.857  -1.791  54.666  1.00 33.54  ? 401 HEM F O2D 1 
HETATM 14095 N  NA  . HEM Q 2 .   ? 39.859  -0.634  48.420  1.00 24.59  ? 401 HEM F NA  1 
HETATM 14096 N  NB  . HEM Q 2 .   ? 42.066  1.037   48.046  1.00 29.29  ? 401 HEM F NB  1 
HETATM 14097 N  NC  . HEM Q 2 .   ? 41.189  2.662   50.298  1.00 23.36  ? 401 HEM F NC  1 
HETATM 14098 N  ND  . HEM Q 2 .   ? 39.141  0.799   50.642  1.00 24.39  ? 401 HEM F ND  1 
HETATM 14099 FE FE  . HEM Q 2 .   ? 40.570  0.892   49.427  1.00 24.82  ? 401 HEM F FE  1 
HETATM 14100 O  O   . HOH R 6 .   ? 12.026  29.925  2.920   1.00 22.14  ? 501 HOH A O   1 
HETATM 14101 O  O   . HOH R 6 .   ? 13.134  25.028  17.028  1.00 29.69  ? 502 HOH A O   1 
HETATM 14102 O  O   . HOH R 6 .   ? 15.864  20.876  23.673  1.00 35.44  ? 503 HOH A O   1 
HETATM 14103 O  O   . HOH R 6 .   ? -2.947  29.535  41.023  1.00 22.89  ? 504 HOH A O   1 
HETATM 14104 O  O   . HOH R 6 .   ? 15.968  29.089  35.115  1.00 34.18  ? 505 HOH A O   1 
HETATM 14105 O  O   . HOH R 6 .   ? 13.130  37.148  4.362   1.00 27.26  ? 506 HOH A O   1 
HETATM 14106 O  O   . HOH R 6 .   ? 9.494   29.182  8.344   1.00 21.29  ? 507 HOH A O   1 
HETATM 14107 O  O   . HOH R 6 .   ? -5.962  32.377  23.588  1.00 29.48  ? 508 HOH A O   1 
HETATM 14108 O  O   . HOH R 6 .   ? -14.395 27.291  22.684  1.00 34.60  ? 509 HOH A O   1 
HETATM 14109 O  O   . HOH R 6 .   ? 22.426  28.321  23.234  1.00 23.06  ? 510 HOH A O   1 
HETATM 14110 O  O   . HOH R 6 .   ? 7.104   18.428  12.496  1.00 19.96  ? 511 HOH A O   1 
HETATM 14111 O  O   . HOH R 6 .   ? 3.897   18.599  13.063  1.00 28.47  ? 512 HOH A O   1 
HETATM 14112 O  O   . HOH R 6 .   ? -2.971  14.509  32.032  1.00 34.27  ? 513 HOH A O   1 
HETATM 14113 O  O   . HOH R 6 .   ? 24.967  22.796  26.226  1.00 19.43  ? 514 HOH A O   1 
HETATM 14114 O  O   . HOH R 6 .   ? -0.441  26.312  19.465  1.00 23.44  ? 515 HOH A O   1 
HETATM 14115 O  O   . HOH R 6 .   ? -6.736  28.936  26.602  1.00 25.81  ? 516 HOH A O   1 
HETATM 14116 O  O   . HOH R 6 .   ? -9.363  33.221  38.946  1.00 25.93  ? 517 HOH A O   1 
HETATM 14117 O  O   . HOH R 6 .   ? 12.924  31.854  5.112   1.00 21.93  ? 518 HOH A O   1 
HETATM 14118 O  O   . HOH R 6 .   ? 23.215  40.559  15.496  1.00 31.02  ? 519 HOH A O   1 
HETATM 14119 O  O   . HOH R 6 .   ? -11.953 33.558  30.630  1.00 33.47  ? 520 HOH A O   1 
HETATM 14120 O  O   . HOH R 6 .   ? 1.379   34.569  20.393  1.00 21.56  ? 521 HOH A O   1 
HETATM 14121 O  O   . HOH R 6 .   ? 12.232  32.334  0.936   1.00 34.31  ? 522 HOH A O   1 
HETATM 14122 O  O   . HOH R 6 .   ? -2.028  33.618  13.735  1.00 31.87  ? 523 HOH A O   1 
HETATM 14123 O  O   . HOH R 6 .   ? -16.096 32.852  35.487  1.00 29.80  ? 524 HOH A O   1 
HETATM 14124 O  O   . HOH R 6 .   ? 8.039   30.893  38.395  1.00 22.94  ? 525 HOH A O   1 
HETATM 14125 O  O   . HOH R 6 .   ? 7.694   38.621  15.683  1.00 31.28  ? 526 HOH A O   1 
HETATM 14126 O  O   . HOH R 6 .   ? 4.363   15.533  28.848  1.00 21.97  ? 527 HOH A O   1 
HETATM 14127 O  O   . HOH R 6 .   ? -0.858  35.528  28.603  1.00 27.30  ? 528 HOH A O   1 
HETATM 14128 O  O   . HOH R 6 .   ? 3.737   29.730  32.060  1.00 25.89  ? 529 HOH A O   1 
HETATM 14129 O  O   . HOH R 6 .   ? 13.631  21.060  24.470  1.00 30.72  ? 530 HOH A O   1 
HETATM 14130 O  O   . HOH R 6 .   ? -6.696  30.753  29.279  1.00 22.75  ? 531 HOH A O   1 
HETATM 14131 O  O   . HOH R 6 .   ? 8.031   19.309  24.789  1.00 22.53  ? 532 HOH A O   1 
HETATM 14132 O  O   . HOH R 6 .   ? 7.751   45.384  19.017  1.00 29.97  ? 533 HOH A O   1 
HETATM 14133 O  O   . HOH R 6 .   ? 20.381  31.048  28.505  1.00 21.66  ? 534 HOH A O   1 
HETATM 14134 O  O   . HOH R 6 .   ? -6.837  28.497  47.004  1.00 24.54  ? 535 HOH A O   1 
HETATM 14135 O  O   . HOH R 6 .   ? -3.062  27.611  20.463  1.00 44.96  ? 536 HOH A O   1 
HETATM 14136 O  O   . HOH R 6 .   ? -7.956  31.034  43.866  1.00 35.14  ? 537 HOH A O   1 
HETATM 14137 O  O   . HOH R 6 .   ? 15.886  45.210  19.222  1.00 38.09  ? 538 HOH A O   1 
HETATM 14138 O  O   . HOH R 6 .   ? -15.291 10.713  27.198  1.00 41.32  ? 539 HOH A O   1 
HETATM 14139 O  O   . HOH R 6 .   ? 15.491  33.238  32.761  1.00 31.88  ? 540 HOH A O   1 
HETATM 14140 O  O   . HOH R 6 .   ? 13.478  24.399  25.836  1.00 24.02  ? 541 HOH A O   1 
HETATM 14141 O  O   . HOH R 6 .   ? 0.161   19.488  37.668  1.00 24.97  ? 542 HOH A O   1 
HETATM 14142 O  O   . HOH R 6 .   ? 9.623   47.155  18.972  1.00 35.92  ? 543 HOH A O   1 
HETATM 14143 O  O   . HOH R 6 .   ? 12.708  24.018  1.703   1.00 35.04  ? 544 HOH A O   1 
HETATM 14144 O  O   . HOH R 6 .   ? 8.862   30.283  4.629   1.00 33.87  ? 545 HOH A O   1 
HETATM 14145 O  O   . HOH R 6 .   ? -10.529 28.253  27.286  1.00 26.92  ? 546 HOH A O   1 
HETATM 14146 O  O   . HOH R 6 .   ? 14.141  28.648  31.583  1.00 23.91  ? 547 HOH A O   1 
HETATM 14147 O  O   . HOH R 6 .   ? 12.357  34.046  3.420   1.00 19.26  ? 548 HOH A O   1 
HETATM 14148 O  O   . HOH R 6 .   ? 14.735  17.554  23.098  1.00 30.04  ? 549 HOH A O   1 
HETATM 14149 O  O   . HOH R 6 .   ? 5.463   37.437  16.626  1.00 25.49  ? 550 HOH A O   1 
HETATM 14150 O  O   . HOH R 6 .   ? -14.539 27.782  25.895  1.00 31.01  ? 551 HOH A O   1 
HETATM 14151 O  O   . HOH R 6 .   ? 11.691  29.921  6.488   1.00 31.59  ? 552 HOH A O   1 
HETATM 14152 O  O   . HOH R 6 .   ? -5.046  11.862  36.889  1.00 34.16  ? 553 HOH A O   1 
HETATM 14153 O  O   . HOH R 6 .   ? 9.838   7.773   16.572  1.00 53.39  ? 554 HOH A O   1 
HETATM 14154 O  O   . HOH R 6 .   ? -5.729  31.428  26.460  1.00 26.20  ? 555 HOH A O   1 
HETATM 14155 O  O   . HOH R 6 .   ? -9.417  30.685  27.534  1.00 32.02  ? 556 HOH A O   1 
HETATM 14156 O  O   . HOH R 6 .   ? 14.310  30.777  33.574  1.00 22.47  ? 557 HOH A O   1 
HETATM 14157 O  O   . HOH R 6 .   ? -8.349  33.477  43.509  1.00 29.04  ? 558 HOH A O   1 
HETATM 14158 O  O   . HOH S 6 .   ? 19.795  -23.828 32.769  1.00 33.56  ? 601 HOH B O   1 
HETATM 14159 O  O   . HOH S 6 .   ? 39.904  -18.661 28.853  1.00 24.82  ? 602 HOH B O   1 
HETATM 14160 O  O   . HOH S 6 .   ? 43.280  -26.747 16.281  1.00 31.92  ? 603 HOH B O   1 
HETATM 14161 O  O   . HOH S 6 .   ? 24.599  -21.871 21.774  1.00 26.54  ? 604 HOH B O   1 
HETATM 14162 O  O   . HOH S 6 .   ? 36.615  -27.735 10.382  1.00 34.41  ? 605 HOH B O   1 
HETATM 14163 O  O   . HOH S 6 .   ? 14.309  -21.921 32.148  1.00 32.43  ? 606 HOH B O   1 
HETATM 14164 O  O   . HOH S 6 .   ? 46.146  -28.294 37.465  1.00 34.31  ? 607 HOH B O   1 
HETATM 14165 O  O   . HOH S 6 .   ? 39.001  -12.707 26.414  1.00 32.29  ? 608 HOH B O   1 
HETATM 14166 O  O   . HOH S 6 .   ? 33.876  -40.948 31.922  1.00 31.67  ? 609 HOH B O   1 
HETATM 14167 O  O   . HOH S 6 .   ? 20.491  -37.832 23.831  1.00 32.76  ? 610 HOH B O   1 
HETATM 14168 O  O   . HOH S 6 .   ? 45.960  -35.982 31.997  1.00 30.58  ? 611 HOH B O   1 
HETATM 14169 O  O   . HOH S 6 .   ? 22.168  -33.360 24.559  1.00 25.32  ? 612 HOH B O   1 
HETATM 14170 O  O   . HOH S 6 .   ? 19.290  -20.646 10.982  1.00 34.35  ? 613 HOH B O   1 
HETATM 14171 O  O   . HOH S 6 .   ? 24.363  -38.955 13.639  1.00 30.80  ? 614 HOH B O   1 
HETATM 14172 O  O   . HOH S 6 .   ? 27.205  -30.297 38.273  1.00 29.86  ? 615 HOH B O   1 
HETATM 14173 O  O   . HOH S 6 .   ? 42.025  -21.331 23.388  1.00 17.48  ? 616 HOH B O   1 
HETATM 14174 O  O   . HOH S 6 .   ? 12.382  -24.315 6.723   1.00 29.89  ? 617 HOH B O   1 
HETATM 14175 O  O   . HOH S 6 .   ? 19.064  -40.276 13.787  1.00 32.43  ? 618 HOH B O   1 
HETATM 14176 O  O   . HOH S 6 .   ? 46.730  -30.120 35.414  1.00 36.65  ? 619 HOH B O   1 
HETATM 14177 O  O   . HOH S 6 .   ? 29.520  -37.934 25.104  1.00 26.82  ? 620 HOH B O   1 
HETATM 14178 O  O   . HOH S 6 .   ? 37.296  -23.428 18.539  1.00 26.65  ? 621 HOH B O   1 
HETATM 14179 O  O   . HOH S 6 .   ? 24.720  -39.311 16.762  1.00 29.45  ? 622 HOH B O   1 
HETATM 14180 O  O   . HOH S 6 .   ? 43.505  -32.139 40.382  1.00 36.53  ? 623 HOH B O   1 
HETATM 14181 O  O   . HOH S 6 .   ? 23.337  -29.066 2.944   1.00 34.33  ? 624 HOH B O   1 
HETATM 14182 O  O   . HOH S 6 .   ? 39.670  -16.890 30.880  1.00 24.01  ? 625 HOH B O   1 
HETATM 14183 O  O   . HOH S 6 .   ? 40.763  -41.401 30.100  1.00 39.67  ? 626 HOH B O   1 
HETATM 14184 O  O   . HOH S 6 .   ? 32.280  -21.469 23.046  1.00 30.32  ? 627 HOH B O   1 
HETATM 14185 O  O   . HOH S 6 .   ? 18.247  -26.341 31.618  1.00 34.08  ? 628 HOH B O   1 
HETATM 14186 O  O   . HOH S 6 .   ? 39.530  -24.262 16.614  1.00 27.91  ? 629 HOH B O   1 
HETATM 14187 O  O   . HOH T 6 .   ? 7.158   -16.002 8.460   1.00 28.20  ? 501 HOH C O   1 
HETATM 14188 O  O   . HOH T 6 .   ? 16.427  -2.388  -16.144 1.00 33.84  ? 502 HOH C O   1 
HETATM 14189 O  O   . HOH T 6 .   ? 6.971   21.041  -11.268 1.00 33.74  ? 503 HOH C O   1 
HETATM 14190 O  O   . HOH T 6 .   ? 1.714   -9.738  10.215  1.00 26.30  ? 504 HOH C O   1 
HETATM 14191 O  O   . HOH T 6 .   ? 3.804   -4.446  2.259   0.65 28.23  ? 505 HOH C O   1 
HETATM 14192 O  O   . HOH T 6 .   ? 20.898  9.336   -3.590  1.00 28.91  ? 506 HOH C O   1 
HETATM 14193 O  O   . HOH T 6 .   ? 8.218   6.349   -14.218 1.00 30.60  ? 507 HOH C O   1 
HETATM 14194 O  O   . HOH T 6 .   ? 2.854   8.679   -12.168 1.00 28.66  ? 508 HOH C O   1 
HETATM 14195 O  O   . HOH T 6 .   ? 9.037   11.730  -14.331 1.00 29.80  ? 509 HOH C O   1 
HETATM 14196 O  O   . HOH T 6 .   ? 0.846   1.837   8.586   1.00 24.82  ? 510 HOH C O   1 
HETATM 14197 O  O   . HOH T 6 .   ? -8.881  0.832   -2.222  1.00 37.29  ? 511 HOH C O   1 
HETATM 14198 O  O   . HOH T 6 .   ? 8.291   5.679   16.712  1.00 33.64  ? 512 HOH C O   1 
HETATM 14199 O  O   . HOH T 6 .   ? 9.632   25.819  -8.100  1.00 31.50  ? 513 HOH C O   1 
HETATM 14200 O  O   . HOH T 6 .   ? 6.527   0.090   12.319  1.00 32.52  ? 514 HOH C O   1 
HETATM 14201 O  O   . HOH T 6 .   ? 9.306   -2.216  -7.478  1.00 22.02  ? 515 HOH C O   1 
HETATM 14202 O  O   . HOH T 6 .   ? 20.832  1.575   -6.719  1.00 26.80  ? 516 HOH C O   1 
HETATM 14203 O  O   . HOH T 6 .   ? -7.182  7.612   7.568   1.00 23.19  ? 517 HOH C O   1 
HETATM 14204 O  O   . HOH T 6 .   ? 3.261   11.373  9.732   1.00 31.45  ? 518 HOH C O   1 
HETATM 14205 O  O   . HOH T 6 .   ? -3.742  -12.624 17.143  1.00 34.33  ? 519 HOH C O   1 
HETATM 14206 O  O   . HOH T 6 .   ? 7.089   17.828  -14.504 1.00 35.35  ? 520 HOH C O   1 
HETATM 14207 O  O   . HOH T 6 .   ? 3.547   9.606   -2.956  1.00 20.34  ? 521 HOH C O   1 
HETATM 14208 O  O   . HOH T 6 .   ? 2.519   11.991  -6.714  1.00 30.24  ? 522 HOH C O   1 
HETATM 14209 O  O   . HOH T 6 .   ? 3.728   -12.221 4.777   1.00 21.52  ? 523 HOH C O   1 
HETATM 14210 O  O   . HOH T 6 .   ? 11.035  3.491   4.453   1.00 26.02  ? 524 HOH C O   1 
HETATM 14211 O  O   . HOH T 6 .   ? -1.803  4.143   -6.758  1.00 22.76  ? 525 HOH C O   1 
HETATM 14212 O  O   . HOH T 6 .   ? 25.722  11.906  -5.801  1.00 30.22  ? 526 HOH C O   1 
HETATM 14213 O  O   . HOH T 6 .   ? -11.421 -3.962  -7.821  1.00 42.62  ? 527 HOH C O   1 
HETATM 14214 O  O   . HOH T 6 .   ? 22.160  5.850   -0.831  1.00 25.74  ? 528 HOH C O   1 
HETATM 14215 O  O   . HOH T 6 .   ? -12.532 -9.698  -1.934  1.00 39.10  ? 529 HOH C O   1 
HETATM 14216 O  O   . HOH T 6 .   ? 3.877   9.951   -5.609  1.00 38.18  ? 530 HOH C O   1 
HETATM 14217 O  O   . HOH T 6 .   ? 8.920   15.297  -16.346 1.00 36.15  ? 531 HOH C O   1 
HETATM 14218 O  O   . HOH T 6 .   ? -6.992  2.187   -3.690  1.00 29.96  ? 532 HOH C O   1 
HETATM 14219 O  O   . HOH T 6 .   ? 3.626   12.862  7.145   1.00 34.00  ? 533 HOH C O   1 
HETATM 14220 O  O   . HOH T 6 .   ? 8.303   -8.618  0.331   1.00 28.67  ? 534 HOH C O   1 
HETATM 14221 O  O   . HOH T 6 .   ? -5.476  -2.521  14.881  1.00 42.94  ? 535 HOH C O   1 
HETATM 14222 O  O   . HOH T 6 .   ? -17.380 -7.726  13.199  1.00 31.65  ? 536 HOH C O   1 
HETATM 14223 O  O   . HOH T 6 .   ? 22.165  2.010   -12.597 1.00 36.51  ? 537 HOH C O   1 
HETATM 14224 O  O   . HOH T 6 .   ? 5.102   7.186   -12.502 1.00 23.59  ? 538 HOH C O   1 
HETATM 14225 O  O   . HOH T 6 .   ? 1.200   -9.539  12.848  1.00 25.21  ? 539 HOH C O   1 
HETATM 14226 O  O   . HOH T 6 .   ? 12.557  -10.352 6.756   1.00 36.80  ? 540 HOH C O   1 
HETATM 14227 O  O   . HOH T 6 .   ? 7.426   26.155  -7.014  1.00 45.62  ? 541 HOH C O   1 
HETATM 14228 O  O   . HOH U 6 .   ? 52.299  26.337  12.761  1.00 36.85  ? 501 HOH D O   1 
HETATM 14229 O  O   . HOH U 6 .   ? 38.911  10.213  13.445  1.00 35.57  ? 502 HOH D O   1 
HETATM 14230 O  O   . HOH U 6 .   ? 45.308  5.344   -1.934  1.00 33.50  ? 503 HOH D O   1 
HETATM 14231 O  O   . HOH U 6 .   ? 45.634  12.756  25.619  1.00 22.59  ? 504 HOH D O   1 
HETATM 14232 O  O   . HOH U 6 .   ? 40.554  32.532  6.837   1.00 33.87  ? 505 HOH D O   1 
HETATM 14233 O  O   . HOH U 6 .   ? 40.073  11.611  10.704  1.00 24.81  ? 506 HOH D O   1 
HETATM 14234 O  O   . HOH U 6 .   ? 30.534  15.876  2.028   1.00 26.62  ? 507 HOH D O   1 
HETATM 14235 O  O   . HOH U 6 .   ? 29.358  26.856  10.217  1.00 38.24  ? 508 HOH D O   1 
HETATM 14236 O  O   . HOH U 6 .   ? 48.772  23.179  21.832  1.00 28.16  ? 509 HOH D O   1 
HETATM 14237 O  O   . HOH U 6 .   ? 34.593  19.530  8.639   1.00 23.57  ? 510 HOH D O   1 
HETATM 14238 O  O   . HOH U 6 .   ? 42.954  6.269   15.345  1.00 31.85  ? 511 HOH D O   1 
HETATM 14239 O  O   . HOH U 6 .   ? 65.798  2.176   5.281   1.00 34.63  ? 512 HOH D O   1 
HETATM 14240 O  O   . HOH U 6 .   ? 55.028  28.666  2.525   1.00 21.78  ? 513 HOH D O   1 
HETATM 14241 O  O   . HOH U 6 .   ? 59.686  4.438   10.418  1.00 30.65  ? 514 HOH D O   1 
HETATM 14242 O  O   . HOH U 6 .   ? 52.105  -12.539 26.134  1.00 30.59  ? 515 HOH D O   1 
HETATM 14243 O  O   . HOH U 6 .   ? 56.368  15.628  10.658  1.00 21.02  ? 516 HOH D O   1 
HETATM 14244 O  O   . HOH U 6 .   ? 54.328  10.063  16.623  1.00 23.17  ? 517 HOH D O   1 
HETATM 14245 O  O   . HOH U 6 .   ? 56.003  26.350  3.972   1.00 24.30  ? 518 HOH D O   1 
HETATM 14246 O  O   . HOH U 6 .   ? 50.177  32.369  5.979   1.00 30.61  ? 519 HOH D O   1 
HETATM 14247 O  O   . HOH U 6 .   ? 53.491  -3.550  30.561  1.00 40.07  ? 520 HOH D O   1 
HETATM 14248 O  O   . HOH U 6 .   ? 38.672  10.409  0.166   1.00 33.21  ? 521 HOH D O   1 
HETATM 14249 O  O   . HOH U 6 .   ? 42.576  29.814  3.085   1.00 29.58  ? 522 HOH D O   1 
HETATM 14250 O  O   . HOH U 6 .   ? 48.868  29.900  2.496   1.00 20.58  ? 523 HOH D O   1 
HETATM 14251 O  O   . HOH U 6 .   ? 66.485  2.292   16.044  1.00 28.18  ? 524 HOH D O   1 
HETATM 14252 O  O   . HOH U 6 .   ? 53.661  24.162  10.877  1.00 27.52  ? 525 HOH D O   1 
HETATM 14253 O  O   . HOH U 6 .   ? 36.789  17.053  3.240   1.00 23.30  ? 526 HOH D O   1 
HETATM 14254 O  O   . HOH U 6 .   ? 50.018  6.517   4.101   1.00 25.24  ? 527 HOH D O   1 
HETATM 14255 O  O   . HOH U 6 .   ? 43.631  -0.325  15.250  1.00 25.79  ? 528 HOH D O   1 
HETATM 14256 O  O   . HOH U 6 .   ? 52.782  31.782  7.943   1.00 42.78  ? 529 HOH D O   1 
HETATM 14257 O  O   . HOH U 6 .   ? 60.188  3.886   7.367   1.00 23.28  ? 530 HOH D O   1 
HETATM 14258 O  O   . HOH U 6 .   ? 33.436  8.736   5.327   1.00 27.68  ? 531 HOH D O   1 
HETATM 14259 O  O   . HOH U 6 .   ? 32.724  20.631  10.440  1.00 21.33  ? 532 HOH D O   1 
HETATM 14260 O  O   . HOH U 6 .   ? 29.463  18.541  1.589   1.00 32.87  ? 533 HOH D O   1 
HETATM 14261 O  O   . HOH U 6 .   ? 40.455  10.885  3.498   1.00 18.02  ? 534 HOH D O   1 
HETATM 14262 O  O   . HOH U 6 .   ? 54.012  28.904  -3.411  1.00 30.09  ? 535 HOH D O   1 
HETATM 14263 O  O   . HOH U 6 .   ? 57.134  12.947  3.797   1.00 34.62  ? 536 HOH D O   1 
HETATM 14264 O  O   . HOH U 6 .   ? 51.938  -8.138  3.738   1.00 25.76  ? 537 HOH D O   1 
HETATM 14265 O  O   . HOH U 6 .   ? 59.980  6.832   9.029   1.00 21.88  ? 538 HOH D O   1 
HETATM 14266 O  O   . HOH U 6 .   ? 66.075  0.165   13.063  1.00 29.71  ? 539 HOH D O   1 
HETATM 14267 O  O   . HOH U 6 .   ? 62.636  1.708   11.036  1.00 24.19  ? 540 HOH D O   1 
HETATM 14268 O  O   . HOH U 6 .   ? 41.455  13.648  -0.778  1.00 26.34  ? 541 HOH D O   1 
HETATM 14269 O  O   . HOH U 6 .   ? 48.442  11.674  25.450  1.00 33.36  ? 542 HOH D O   1 
HETATM 14270 O  O   . HOH U 6 .   ? 57.568  24.104  11.202  1.00 35.01  ? 543 HOH D O   1 
HETATM 14271 O  O   . HOH U 6 .   ? 36.267  -6.181  21.391  1.00 42.95  ? 544 HOH D O   1 
HETATM 14272 O  O   . HOH U 6 .   ? 39.213  25.414  18.581  1.00 41.11  ? 545 HOH D O   1 
HETATM 14273 O  O   . HOH U 6 .   ? 40.955  11.203  0.689   1.00 25.68  ? 546 HOH D O   1 
HETATM 14274 O  O   . HOH U 6 .   ? 62.773  3.910   9.183   1.00 29.02  ? 547 HOH D O   1 
HETATM 14275 O  O   . HOH U 6 .   ? 49.799  32.040  3.343   1.00 34.95  ? 548 HOH D O   1 
HETATM 14276 O  O   . HOH U 6 .   ? 68.959  -10.816 15.173  1.00 34.30  ? 549 HOH D O   1 
HETATM 14277 O  O   . HOH V 6 .   ? 2.640   -23.044 53.370  1.00 30.02  ? 501 HOH E O   1 
HETATM 14278 O  O   . HOH V 6 .   ? -4.477  1.794   32.898  1.00 28.82  ? 502 HOH E O   1 
HETATM 14279 O  O   . HOH V 6 .   ? 11.587  -21.422 33.258  1.00 27.84  ? 503 HOH E O   1 
HETATM 14280 O  O   . HOH V 6 .   ? 3.548   -6.160  60.418  1.00 25.84  ? 504 HOH E O   1 
HETATM 14281 O  O   . HOH V 6 .   ? -1.111  -10.174 38.450  0.60 27.29  ? 505 HOH E O   1 
HETATM 14282 O  O   . HOH V 6 .   ? 6.603   -21.972 45.082  1.00 23.63  ? 506 HOH E O   1 
HETATM 14283 O  O   . HOH V 6 .   ? -1.302  -2.739  50.511  1.00 40.06  ? 507 HOH E O   1 
HETATM 14284 O  O   . HOH V 6 .   ? 6.010   -19.879 54.925  1.00 33.13  ? 508 HOH E O   1 
HETATM 14285 O  O   . HOH V 6 .   ? -13.922 -21.880 43.322  1.00 32.27  ? 509 HOH E O   1 
HETATM 14286 O  O   . HOH V 6 .   ? 10.391  -26.841 58.179  1.00 21.34  ? 510 HOH E O   1 
HETATM 14287 O  O   . HOH V 6 .   ? 17.959  -10.151 51.041  1.00 33.61  ? 511 HOH E O   1 
HETATM 14288 O  O   . HOH V 6 .   ? -16.586 -21.050 42.303  1.00 42.23  ? 512 HOH E O   1 
HETATM 14289 O  O   . HOH V 6 .   ? 4.046   -18.093 56.799  1.00 27.54  ? 513 HOH E O   1 
HETATM 14290 O  O   . HOH V 6 .   ? 23.278  -24.817 61.806  1.00 36.86  ? 514 HOH E O   1 
HETATM 14291 O  O   . HOH V 6 .   ? 17.292  -6.479  48.603  1.00 31.90  ? 515 HOH E O   1 
HETATM 14292 O  O   . HOH V 6 .   ? 1.203   -25.917 31.586  1.00 28.90  ? 516 HOH E O   1 
HETATM 14293 O  O   . HOH V 6 .   ? -1.868  -21.690 46.180  1.00 27.08  ? 517 HOH E O   1 
HETATM 14294 O  O   . HOH V 6 .   ? -2.685  -16.910 53.370  1.00 37.04  ? 518 HOH E O   1 
HETATM 14295 O  O   . HOH V 6 .   ? 14.691  -9.163  43.994  1.00 28.42  ? 519 HOH E O   1 
HETATM 14296 O  O   . HOH V 6 .   ? 9.917   -11.214 39.750  1.00 31.77  ? 520 HOH E O   1 
HETATM 14297 O  O   . HOH V 6 .   ? -1.114  -4.545  41.363  1.00 24.79  ? 521 HOH E O   1 
HETATM 14298 O  O   . HOH V 6 .   ? 8.075   -20.999 58.027  1.00 24.88  ? 522 HOH E O   1 
HETATM 14299 O  O   . HOH V 6 .   ? 11.311  -5.115  59.409  1.00 37.35  ? 523 HOH E O   1 
HETATM 14300 O  O   . HOH V 6 .   ? 8.106   -22.914 65.013  1.00 27.42  ? 524 HOH E O   1 
HETATM 14301 O  O   . HOH V 6 .   ? 10.093  -24.169 60.225  1.00 22.22  ? 525 HOH E O   1 
HETATM 14302 O  O   . HOH V 6 .   ? 12.260  -28.943 57.492  1.00 29.30  ? 526 HOH E O   1 
HETATM 14303 O  O   . HOH V 6 .   ? 21.981  -14.684 30.045  1.00 38.39  ? 527 HOH E O   1 
HETATM 14304 O  O   . HOH V 6 .   ? 11.876  -22.892 35.849  1.00 32.72  ? 528 HOH E O   1 
HETATM 14305 O  O   . HOH V 6 .   ? 3.060   -20.415 54.221  1.00 24.37  ? 529 HOH E O   1 
HETATM 14306 O  O   . HOH V 6 .   ? 5.183   -21.214 57.978  1.00 25.90  ? 530 HOH E O   1 
HETATM 14307 O  O   . HOH W 6 .   ? 39.915  32.072  57.385  1.00 28.04  ? 501 HOH F O   1 
HETATM 14308 O  O   . HOH W 6 .   ? 35.680  11.024  24.274  1.00 32.99  ? 502 HOH F O   1 
HETATM 14309 O  O   . HOH W 6 .   ? 46.797  14.601  43.471  1.00 29.59  ? 503 HOH F O   1 
HETATM 14310 O  O   . HOH W 6 .   ? 34.669  0.416   55.334  1.00 36.59  ? 504 HOH F O   1 
HETATM 14311 O  O   . HOH W 6 .   ? 43.740  1.608   39.929  1.00 27.95  ? 505 HOH F O   1 
HETATM 14312 O  O   . HOH W 6 .   ? 36.394  3.143   44.351  1.00 26.53  ? 506 HOH F O   1 
HETATM 14313 O  O   . HOH W 6 .   ? 32.070  20.932  58.823  1.00 29.86  ? 507 HOH F O   1 
HETATM 14314 O  O   . HOH W 6 .   ? 31.548  9.542   56.791  1.00 36.61  ? 508 HOH F O   1 
HETATM 14315 O  O   . HOH W 6 .   ? 28.883  19.252  41.027  1.00 30.74  ? 509 HOH F O   1 
HETATM 14316 O  O   . HOH W 6 .   ? 28.756  12.799  36.956  1.00 35.00  ? 510 HOH F O   1 
HETATM 14317 O  O   . HOH W 6 .   ? 29.923  22.381  38.365  1.00 42.81  ? 511 HOH F O   1 
HETATM 14318 O  O   . HOH W 6 .   ? 35.829  3.999   41.089  1.00 31.05  ? 512 HOH F O   1 
HETATM 14319 O  O   . HOH W 6 .   ? 33.901  2.986   50.878  1.00 22.05  ? 513 HOH F O   1 
HETATM 14320 O  O   . HOH W 6 .   ? 44.406  21.303  50.337  1.00 36.17  ? 514 HOH F O   1 
HETATM 14321 O  O   . HOH W 6 .   ? 39.440  2.240   48.062  0.60 26.02  ? 515 HOH F O   1 
HETATM 14322 O  O   . HOH W 6 .   ? 25.368  27.790  31.281  1.00 34.06  ? 516 HOH F O   1 
HETATM 14323 O  O   . HOH W 6 .   ? 28.208  26.471  60.952  1.00 33.68  ? 517 HOH F O   1 
HETATM 14324 O  O   . HOH W 6 .   ? 49.830  11.040  50.767  1.00 25.98  ? 518 HOH F O   1 
HETATM 14325 O  O   . HOH W 6 .   ? 35.575  -4.185  50.693  1.00 25.44  ? 519 HOH F O   1 
HETATM 14326 O  O   . HOH W 6 .   ? 44.915  25.450  50.309  1.00 25.28  ? 520 HOH F O   1 
HETATM 14327 O  O   . HOH W 6 .   ? 28.693  19.603  48.180  1.00 26.10  ? 521 HOH F O   1 
HETATM 14328 O  O   . HOH W 6 .   ? 34.159  31.008  31.086  1.00 43.36  ? 522 HOH F O   1 
HETATM 14329 O  O   . HOH W 6 .   ? 43.561  21.440  53.278  1.00 24.31  ? 523 HOH F O   1 
HETATM 14330 O  O   . HOH W 6 .   ? 36.475  9.646   40.111  1.00 28.38  ? 524 HOH F O   1 
HETATM 14331 O  O   . HOH W 6 .   ? 29.223  28.105  40.413  1.00 23.01  ? 525 HOH F O   1 
HETATM 14332 O  O   . HOH W 6 .   ? 32.286  15.008  39.653  1.00 22.23  ? 526 HOH F O   1 
HETATM 14333 O  O   . HOH W 6 .   ? 42.692  37.925  40.611  1.00 35.60  ? 527 HOH F O   1 
HETATM 14334 O  O   . HOH W 6 .   ? 31.695  22.683  40.894  1.00 26.42  ? 528 HOH F O   1 
HETATM 14335 O  O   . HOH W 6 .   ? 45.928  7.644   32.470  1.00 28.80  ? 529 HOH F O   1 
HETATM 14336 O  O   . HOH W 6 .   ? 45.948  19.655  52.248  1.00 22.03  ? 530 HOH F O   1 
HETATM 14337 O  O   . HOH W 6 .   ? 37.573  -8.347  43.308  1.00 28.77  ? 531 HOH F O   1 
HETATM 14338 O  O   . HOH W 6 .   ? 28.768  24.258  52.304  1.00 32.59  ? 532 HOH F O   1 
HETATM 14339 O  O   . HOH W 6 .   ? 45.710  23.870  52.764  1.00 32.06  ? 533 HOH F O   1 
HETATM 14340 O  O   . HOH W 6 .   ? 40.027  -15.919 42.350  1.00 40.02  ? 534 HOH F O   1 
HETATM 14341 O  O   . HOH W 6 .   ? 33.236  2.772   53.905  1.00 23.98  ? 535 HOH F O   1 
HETATM 14342 O  O   . HOH W 6 .   ? 52.844  5.370   50.650  1.00 32.87  ? 536 HOH F O   1 
# 
