data_9EVC
# 
_entry.id   9EVC 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EVC         pdb_00009evc 10.2210/pdb9evc/pdb 
WWPDB D_1292137634 ?            ?                   
EMDB  EMD-19998    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-02-05 
2 'Structure model' 1 1 2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
5 2 'Structure model' '_citation.title'                   
6 2 'Structure model' '_citation_author.identifier_ORCID' 
7 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EVC 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'E1-Ca Structure' 
_pdbx_database_related.db_id          EMD-19998 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              magnus.p.andersson@umu.se 
_pdbx_contact_author.name_first         Magnus 
_pdbx_contact_author.name_last          Andersson 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3364-6647 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Prabudiansyah, I.' 1 ? 
'Andersson, M.'     2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Adv' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2375-2548 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            10 
_citation.language                  ? 
_citation.page_first                eadp2916 
_citation.page_last                 eadp2916 
_citation.title                     'Dephosphorylation and ion binding in prokaryotic calcium transport.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/sciadv.adp2916 
_citation.pdbx_database_id_PubMed   39908574 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Prabudiansyah, I.' 1 0000-0001-7133-6933 
primary 'Oradd, F.'         2 0000-0002-0706-7414 
primary 'Magkakis, K.'      3 0009-0006-3715-1170 
primary 'Pounot, K.'        4 0000-0003-2217-1081 
primary 'Levantino, M.'     5 0000-0002-1224-4809 
primary 'Andersson, M.'     6 0000-0002-3364-6647 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Calcium-transporting ATPase lmo0841' 95695.539 1 7.2.2.10 ? ? ? 
2 non-polymer syn 'CALCIUM ION'                         40.078    1 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        LMCA1 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;AEIYRKSAAETFTQLEATEKGLTTSEVTKRQEKYGFNELKNKKKDPLWKLFLETFKDPMVIVLVIAALVQLVLGEVVESL
IIFLVLIVNSIISVVQTRKAESSLDALREMSAPVAKVIRDGSKQSIHARELVPGDVVILDAGDFVPADGRLFESGSLKID
EGMLTGESEAVEKYIDTIPDEVGLGDRVNMVFSGSLVVYGRGMFVVTGTASETEIGKIAGLLETAEAKQTPLQRKLESFS
KKLGLGILALCVLIFAVEAGRVLLGDNSADMATAILNAFMFAVAVAVAAIPEALSSIVTIVLAVGTNKMAKQHAIIRKLP
AVETLGSTSVICTDKTGTLTQNKMTVVDYYLPDGTKENFPESPENWSEGERRLIHIAVLCNDSNINSEGKELGDPTEVAL
IAFSNKNNQDYNEIREKFIREGEIPFDSDRKLMSTLHTFNENKAMLTKGGPDVMFARCSYVFLDGEEKPMTEEILAKLKE
TNEEFSNQALRVLAYGYKRMPADTTELKLEDEQDIVLVGLTAMIDPPREAVYASIEESKKAGIRTVMITGDHKTTAQAIG
RDIGLMDADDIALTGQELDAMPEEELDKKLEHIAVYARVSPENKIRIVKAWQKKGKITAMTGDGVNDAPALKQADIGVAM
GSGTDVAKDSAAMILTDDNFVSIVDAVGVGRTVFDNIKKSIAYLFAGNLGAIIAILFALVLDWINPFTALQLLFINLVND
SLPAIALGMEKAEPDVMKRKPRDINEGIFAGGTMRAVISRGVLIGIAVIISQYIGMQISPEMSVAMAFTTLILARTLQTF
AARSNVQTAFGAGFFSNKYVIGAVLLCFVLYGITVLPGAREIFSIPASFGLHEWSIAAGLALAAVVMMEIIKVVQNKFFK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;AEIYRKSAAETFTQLEATEKGLTTSEVTKRQEKYGFNELKNKKKDPLWKLFLETFKDPMVIVLVIAALVQLVLGEVVESL
IIFLVLIVNSIISVVQTRKAESSLDALREMSAPVAKVIRDGSKQSIHARELVPGDVVILDAGDFVPADGRLFESGSLKID
EGMLTGESEAVEKYIDTIPDEVGLGDRVNMVFSGSLVVYGRGMFVVTGTASETEIGKIAGLLETAEAKQTPLQRKLESFS
KKLGLGILALCVLIFAVEAGRVLLGDNSADMATAILNAFMFAVAVAVAAIPEALSSIVTIVLAVGTNKMAKQHAIIRKLP
AVETLGSTSVICTDKTGTLTQNKMTVVDYYLPDGTKENFPESPENWSEGERRLIHIAVLCNDSNINSEGKELGDPTEVAL
IAFSNKNNQDYNEIREKFIREGEIPFDSDRKLMSTLHTFNENKAMLTKGGPDVMFARCSYVFLDGEEKPMTEEILAKLKE
TNEEFSNQALRVLAYGYKRMPADTTELKLEDEQDIVLVGLTAMIDPPREAVYASIEESKKAGIRTVMITGDHKTTAQAIG
RDIGLMDADDIALTGQELDAMPEEELDKKLEHIAVYARVSPENKIRIVKAWQKKGKITAMTGDGVNDAPALKQADIGVAM
GSGTDVAKDSAAMILTDDNFVSIVDAVGVGRTVFDNIKKSIAYLFAGNLGAIIAILFALVLDWINPFTALQLLFINLVND
SLPAIALGMEKAEPDVMKRKPRDINEGIFAGGTMRAVISRGVLIGIAVIISQYIGMQISPEMSVAMAFTTLILARTLQTF
AARSNVQTAFGAGFFSNKYVIGAVLLCFVLYGITVLPGAREIFSIPASFGLHEWSIAAGLALAAVVMMEIIKVVQNKFFK
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'CALCIUM ION' 
_pdbx_entity_nonpoly.comp_id     CA 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   GLU n 
1 3   ILE n 
1 4   TYR n 
1 5   ARG n 
1 6   LYS n 
1 7   SER n 
1 8   ALA n 
1 9   ALA n 
1 10  GLU n 
1 11  THR n 
1 12  PHE n 
1 13  THR n 
1 14  GLN n 
1 15  LEU n 
1 16  GLU n 
1 17  ALA n 
1 18  THR n 
1 19  GLU n 
1 20  LYS n 
1 21  GLY n 
1 22  LEU n 
1 23  THR n 
1 24  THR n 
1 25  SER n 
1 26  GLU n 
1 27  VAL n 
1 28  THR n 
1 29  LYS n 
1 30  ARG n 
1 31  GLN n 
1 32  GLU n 
1 33  LYS n 
1 34  TYR n 
1 35  GLY n 
1 36  PHE n 
1 37  ASN n 
1 38  GLU n 
1 39  LEU n 
1 40  LYS n 
1 41  ASN n 
1 42  LYS n 
1 43  LYS n 
1 44  LYS n 
1 45  ASP n 
1 46  PRO n 
1 47  LEU n 
1 48  TRP n 
1 49  LYS n 
1 50  LEU n 
1 51  PHE n 
1 52  LEU n 
1 53  GLU n 
1 54  THR n 
1 55  PHE n 
1 56  LYS n 
1 57  ASP n 
1 58  PRO n 
1 59  MET n 
1 60  VAL n 
1 61  ILE n 
1 62  VAL n 
1 63  LEU n 
1 64  VAL n 
1 65  ILE n 
1 66  ALA n 
1 67  ALA n 
1 68  LEU n 
1 69  VAL n 
1 70  GLN n 
1 71  LEU n 
1 72  VAL n 
1 73  LEU n 
1 74  GLY n 
1 75  GLU n 
1 76  VAL n 
1 77  VAL n 
1 78  GLU n 
1 79  SER n 
1 80  LEU n 
1 81  ILE n 
1 82  ILE n 
1 83  PHE n 
1 84  LEU n 
1 85  VAL n 
1 86  LEU n 
1 87  ILE n 
1 88  VAL n 
1 89  ASN n 
1 90  SER n 
1 91  ILE n 
1 92  ILE n 
1 93  SER n 
1 94  VAL n 
1 95  VAL n 
1 96  GLN n 
1 97  THR n 
1 98  ARG n 
1 99  LYS n 
1 100 ALA n 
1 101 GLU n 
1 102 SER n 
1 103 SER n 
1 104 LEU n 
1 105 ASP n 
1 106 ALA n 
1 107 LEU n 
1 108 ARG n 
1 109 GLU n 
1 110 MET n 
1 111 SER n 
1 112 ALA n 
1 113 PRO n 
1 114 VAL n 
1 115 ALA n 
1 116 LYS n 
1 117 VAL n 
1 118 ILE n 
1 119 ARG n 
1 120 ASP n 
1 121 GLY n 
1 122 SER n 
1 123 LYS n 
1 124 GLN n 
1 125 SER n 
1 126 ILE n 
1 127 HIS n 
1 128 ALA n 
1 129 ARG n 
1 130 GLU n 
1 131 LEU n 
1 132 VAL n 
1 133 PRO n 
1 134 GLY n 
1 135 ASP n 
1 136 VAL n 
1 137 VAL n 
1 138 ILE n 
1 139 LEU n 
1 140 ASP n 
1 141 ALA n 
1 142 GLY n 
1 143 ASP n 
1 144 PHE n 
1 145 VAL n 
1 146 PRO n 
1 147 ALA n 
1 148 ASP n 
1 149 GLY n 
1 150 ARG n 
1 151 LEU n 
1 152 PHE n 
1 153 GLU n 
1 154 SER n 
1 155 GLY n 
1 156 SER n 
1 157 LEU n 
1 158 LYS n 
1 159 ILE n 
1 160 ASP n 
1 161 GLU n 
1 162 GLY n 
1 163 MET n 
1 164 LEU n 
1 165 THR n 
1 166 GLY n 
1 167 GLU n 
1 168 SER n 
1 169 GLU n 
1 170 ALA n 
1 171 VAL n 
1 172 GLU n 
1 173 LYS n 
1 174 TYR n 
1 175 ILE n 
1 176 ASP n 
1 177 THR n 
1 178 ILE n 
1 179 PRO n 
1 180 ASP n 
1 181 GLU n 
1 182 VAL n 
1 183 GLY n 
1 184 LEU n 
1 185 GLY n 
1 186 ASP n 
1 187 ARG n 
1 188 VAL n 
1 189 ASN n 
1 190 MET n 
1 191 VAL n 
1 192 PHE n 
1 193 SER n 
1 194 GLY n 
1 195 SER n 
1 196 LEU n 
1 197 VAL n 
1 198 VAL n 
1 199 TYR n 
1 200 GLY n 
1 201 ARG n 
1 202 GLY n 
1 203 MET n 
1 204 PHE n 
1 205 VAL n 
1 206 VAL n 
1 207 THR n 
1 208 GLY n 
1 209 THR n 
1 210 ALA n 
1 211 SER n 
1 212 GLU n 
1 213 THR n 
1 214 GLU n 
1 215 ILE n 
1 216 GLY n 
1 217 LYS n 
1 218 ILE n 
1 219 ALA n 
1 220 GLY n 
1 221 LEU n 
1 222 LEU n 
1 223 GLU n 
1 224 THR n 
1 225 ALA n 
1 226 GLU n 
1 227 ALA n 
1 228 LYS n 
1 229 GLN n 
1 230 THR n 
1 231 PRO n 
1 232 LEU n 
1 233 GLN n 
1 234 ARG n 
1 235 LYS n 
1 236 LEU n 
1 237 GLU n 
1 238 SER n 
1 239 PHE n 
1 240 SER n 
1 241 LYS n 
1 242 LYS n 
1 243 LEU n 
1 244 GLY n 
1 245 LEU n 
1 246 GLY n 
1 247 ILE n 
1 248 LEU n 
1 249 ALA n 
1 250 LEU n 
1 251 CYS n 
1 252 VAL n 
1 253 LEU n 
1 254 ILE n 
1 255 PHE n 
1 256 ALA n 
1 257 VAL n 
1 258 GLU n 
1 259 ALA n 
1 260 GLY n 
1 261 ARG n 
1 262 VAL n 
1 263 LEU n 
1 264 LEU n 
1 265 GLY n 
1 266 ASP n 
1 267 ASN n 
1 268 SER n 
1 269 ALA n 
1 270 ASP n 
1 271 MET n 
1 272 ALA n 
1 273 THR n 
1 274 ALA n 
1 275 ILE n 
1 276 LEU n 
1 277 ASN n 
1 278 ALA n 
1 279 PHE n 
1 280 MET n 
1 281 PHE n 
1 282 ALA n 
1 283 VAL n 
1 284 ALA n 
1 285 VAL n 
1 286 ALA n 
1 287 VAL n 
1 288 ALA n 
1 289 ALA n 
1 290 ILE n 
1 291 PRO n 
1 292 GLU n 
1 293 ALA n 
1 294 LEU n 
1 295 SER n 
1 296 SER n 
1 297 ILE n 
1 298 VAL n 
1 299 THR n 
1 300 ILE n 
1 301 VAL n 
1 302 LEU n 
1 303 ALA n 
1 304 VAL n 
1 305 GLY n 
1 306 THR n 
1 307 ASN n 
1 308 LYS n 
1 309 MET n 
1 310 ALA n 
1 311 LYS n 
1 312 GLN n 
1 313 HIS n 
1 314 ALA n 
1 315 ILE n 
1 316 ILE n 
1 317 ARG n 
1 318 LYS n 
1 319 LEU n 
1 320 PRO n 
1 321 ALA n 
1 322 VAL n 
1 323 GLU n 
1 324 THR n 
1 325 LEU n 
1 326 GLY n 
1 327 SER n 
1 328 THR n 
1 329 SER n 
1 330 VAL n 
1 331 ILE n 
1 332 CYS n 
1 333 THR n 
1 334 ASP n 
1 335 LYS n 
1 336 THR n 
1 337 GLY n 
1 338 THR n 
1 339 LEU n 
1 340 THR n 
1 341 GLN n 
1 342 ASN n 
1 343 LYS n 
1 344 MET n 
1 345 THR n 
1 346 VAL n 
1 347 VAL n 
1 348 ASP n 
1 349 TYR n 
1 350 TYR n 
1 351 LEU n 
1 352 PRO n 
1 353 ASP n 
1 354 GLY n 
1 355 THR n 
1 356 LYS n 
1 357 GLU n 
1 358 ASN n 
1 359 PHE n 
1 360 PRO n 
1 361 GLU n 
1 362 SER n 
1 363 PRO n 
1 364 GLU n 
1 365 ASN n 
1 366 TRP n 
1 367 SER n 
1 368 GLU n 
1 369 GLY n 
1 370 GLU n 
1 371 ARG n 
1 372 ARG n 
1 373 LEU n 
1 374 ILE n 
1 375 HIS n 
1 376 ILE n 
1 377 ALA n 
1 378 VAL n 
1 379 LEU n 
1 380 CYS n 
1 381 ASN n 
1 382 ASP n 
1 383 SER n 
1 384 ASN n 
1 385 ILE n 
1 386 ASN n 
1 387 SER n 
1 388 GLU n 
1 389 GLY n 
1 390 LYS n 
1 391 GLU n 
1 392 LEU n 
1 393 GLY n 
1 394 ASP n 
1 395 PRO n 
1 396 THR n 
1 397 GLU n 
1 398 VAL n 
1 399 ALA n 
1 400 LEU n 
1 401 ILE n 
1 402 ALA n 
1 403 PHE n 
1 404 SER n 
1 405 ASN n 
1 406 LYS n 
1 407 ASN n 
1 408 ASN n 
1 409 GLN n 
1 410 ASP n 
1 411 TYR n 
1 412 ASN n 
1 413 GLU n 
1 414 ILE n 
1 415 ARG n 
1 416 GLU n 
1 417 LYS n 
1 418 PHE n 
1 419 ILE n 
1 420 ARG n 
1 421 GLU n 
1 422 GLY n 
1 423 GLU n 
1 424 ILE n 
1 425 PRO n 
1 426 PHE n 
1 427 ASP n 
1 428 SER n 
1 429 ASP n 
1 430 ARG n 
1 431 LYS n 
1 432 LEU n 
1 433 MET n 
1 434 SER n 
1 435 THR n 
1 436 LEU n 
1 437 HIS n 
1 438 THR n 
1 439 PHE n 
1 440 ASN n 
1 441 GLU n 
1 442 ASN n 
1 443 LYS n 
1 444 ALA n 
1 445 MET n 
1 446 LEU n 
1 447 THR n 
1 448 LYS n 
1 449 GLY n 
1 450 GLY n 
1 451 PRO n 
1 452 ASP n 
1 453 VAL n 
1 454 MET n 
1 455 PHE n 
1 456 ALA n 
1 457 ARG n 
1 458 CYS n 
1 459 SER n 
1 460 TYR n 
1 461 VAL n 
1 462 PHE n 
1 463 LEU n 
1 464 ASP n 
1 465 GLY n 
1 466 GLU n 
1 467 GLU n 
1 468 LYS n 
1 469 PRO n 
1 470 MET n 
1 471 THR n 
1 472 GLU n 
1 473 GLU n 
1 474 ILE n 
1 475 LEU n 
1 476 ALA n 
1 477 LYS n 
1 478 LEU n 
1 479 LYS n 
1 480 GLU n 
1 481 THR n 
1 482 ASN n 
1 483 GLU n 
1 484 GLU n 
1 485 PHE n 
1 486 SER n 
1 487 ASN n 
1 488 GLN n 
1 489 ALA n 
1 490 LEU n 
1 491 ARG n 
1 492 VAL n 
1 493 LEU n 
1 494 ALA n 
1 495 TYR n 
1 496 GLY n 
1 497 TYR n 
1 498 LYS n 
1 499 ARG n 
1 500 MET n 
1 501 PRO n 
1 502 ALA n 
1 503 ASP n 
1 504 THR n 
1 505 THR n 
1 506 GLU n 
1 507 LEU n 
1 508 LYS n 
1 509 LEU n 
1 510 GLU n 
1 511 ASP n 
1 512 GLU n 
1 513 GLN n 
1 514 ASP n 
1 515 ILE n 
1 516 VAL n 
1 517 LEU n 
1 518 VAL n 
1 519 GLY n 
1 520 LEU n 
1 521 THR n 
1 522 ALA n 
1 523 MET n 
1 524 ILE n 
1 525 ASP n 
1 526 PRO n 
1 527 PRO n 
1 528 ARG n 
1 529 GLU n 
1 530 ALA n 
1 531 VAL n 
1 532 TYR n 
1 533 ALA n 
1 534 SER n 
1 535 ILE n 
1 536 GLU n 
1 537 GLU n 
1 538 SER n 
1 539 LYS n 
1 540 LYS n 
1 541 ALA n 
1 542 GLY n 
1 543 ILE n 
1 544 ARG n 
1 545 THR n 
1 546 VAL n 
1 547 MET n 
1 548 ILE n 
1 549 THR n 
1 550 GLY n 
1 551 ASP n 
1 552 HIS n 
1 553 LYS n 
1 554 THR n 
1 555 THR n 
1 556 ALA n 
1 557 GLN n 
1 558 ALA n 
1 559 ILE n 
1 560 GLY n 
1 561 ARG n 
1 562 ASP n 
1 563 ILE n 
1 564 GLY n 
1 565 LEU n 
1 566 MET n 
1 567 ASP n 
1 568 ALA n 
1 569 ASP n 
1 570 ASP n 
1 571 ILE n 
1 572 ALA n 
1 573 LEU n 
1 574 THR n 
1 575 GLY n 
1 576 GLN n 
1 577 GLU n 
1 578 LEU n 
1 579 ASP n 
1 580 ALA n 
1 581 MET n 
1 582 PRO n 
1 583 GLU n 
1 584 GLU n 
1 585 GLU n 
1 586 LEU n 
1 587 ASP n 
1 588 LYS n 
1 589 LYS n 
1 590 LEU n 
1 591 GLU n 
1 592 HIS n 
1 593 ILE n 
1 594 ALA n 
1 595 VAL n 
1 596 TYR n 
1 597 ALA n 
1 598 ARG n 
1 599 VAL n 
1 600 SER n 
1 601 PRO n 
1 602 GLU n 
1 603 ASN n 
1 604 LYS n 
1 605 ILE n 
1 606 ARG n 
1 607 ILE n 
1 608 VAL n 
1 609 LYS n 
1 610 ALA n 
1 611 TRP n 
1 612 GLN n 
1 613 LYS n 
1 614 LYS n 
1 615 GLY n 
1 616 LYS n 
1 617 ILE n 
1 618 THR n 
1 619 ALA n 
1 620 MET n 
1 621 THR n 
1 622 GLY n 
1 623 ASP n 
1 624 GLY n 
1 625 VAL n 
1 626 ASN n 
1 627 ASP n 
1 628 ALA n 
1 629 PRO n 
1 630 ALA n 
1 631 LEU n 
1 632 LYS n 
1 633 GLN n 
1 634 ALA n 
1 635 ASP n 
1 636 ILE n 
1 637 GLY n 
1 638 VAL n 
1 639 ALA n 
1 640 MET n 
1 641 GLY n 
1 642 SER n 
1 643 GLY n 
1 644 THR n 
1 645 ASP n 
1 646 VAL n 
1 647 ALA n 
1 648 LYS n 
1 649 ASP n 
1 650 SER n 
1 651 ALA n 
1 652 ALA n 
1 653 MET n 
1 654 ILE n 
1 655 LEU n 
1 656 THR n 
1 657 ASP n 
1 658 ASP n 
1 659 ASN n 
1 660 PHE n 
1 661 VAL n 
1 662 SER n 
1 663 ILE n 
1 664 VAL n 
1 665 ASP n 
1 666 ALA n 
1 667 VAL n 
1 668 GLY n 
1 669 VAL n 
1 670 GLY n 
1 671 ARG n 
1 672 THR n 
1 673 VAL n 
1 674 PHE n 
1 675 ASP n 
1 676 ASN n 
1 677 ILE n 
1 678 LYS n 
1 679 LYS n 
1 680 SER n 
1 681 ILE n 
1 682 ALA n 
1 683 TYR n 
1 684 LEU n 
1 685 PHE n 
1 686 ALA n 
1 687 GLY n 
1 688 ASN n 
1 689 LEU n 
1 690 GLY n 
1 691 ALA n 
1 692 ILE n 
1 693 ILE n 
1 694 ALA n 
1 695 ILE n 
1 696 LEU n 
1 697 PHE n 
1 698 ALA n 
1 699 LEU n 
1 700 VAL n 
1 701 LEU n 
1 702 ASP n 
1 703 TRP n 
1 704 ILE n 
1 705 ASN n 
1 706 PRO n 
1 707 PHE n 
1 708 THR n 
1 709 ALA n 
1 710 LEU n 
1 711 GLN n 
1 712 LEU n 
1 713 LEU n 
1 714 PHE n 
1 715 ILE n 
1 716 ASN n 
1 717 LEU n 
1 718 VAL n 
1 719 ASN n 
1 720 ASP n 
1 721 SER n 
1 722 LEU n 
1 723 PRO n 
1 724 ALA n 
1 725 ILE n 
1 726 ALA n 
1 727 LEU n 
1 728 GLY n 
1 729 MET n 
1 730 GLU n 
1 731 LYS n 
1 732 ALA n 
1 733 GLU n 
1 734 PRO n 
1 735 ASP n 
1 736 VAL n 
1 737 MET n 
1 738 LYS n 
1 739 ARG n 
1 740 LYS n 
1 741 PRO n 
1 742 ARG n 
1 743 ASP n 
1 744 ILE n 
1 745 ASN n 
1 746 GLU n 
1 747 GLY n 
1 748 ILE n 
1 749 PHE n 
1 750 ALA n 
1 751 GLY n 
1 752 GLY n 
1 753 THR n 
1 754 MET n 
1 755 ARG n 
1 756 ALA n 
1 757 VAL n 
1 758 ILE n 
1 759 SER n 
1 760 ARG n 
1 761 GLY n 
1 762 VAL n 
1 763 LEU n 
1 764 ILE n 
1 765 GLY n 
1 766 ILE n 
1 767 ALA n 
1 768 VAL n 
1 769 ILE n 
1 770 ILE n 
1 771 SER n 
1 772 GLN n 
1 773 TYR n 
1 774 ILE n 
1 775 GLY n 
1 776 MET n 
1 777 GLN n 
1 778 ILE n 
1 779 SER n 
1 780 PRO n 
1 781 GLU n 
1 782 MET n 
1 783 SER n 
1 784 VAL n 
1 785 ALA n 
1 786 MET n 
1 787 ALA n 
1 788 PHE n 
1 789 THR n 
1 790 THR n 
1 791 LEU n 
1 792 ILE n 
1 793 LEU n 
1 794 ALA n 
1 795 ARG n 
1 796 THR n 
1 797 LEU n 
1 798 GLN n 
1 799 THR n 
1 800 PHE n 
1 801 ALA n 
1 802 ALA n 
1 803 ARG n 
1 804 SER n 
1 805 ASN n 
1 806 VAL n 
1 807 GLN n 
1 808 THR n 
1 809 ALA n 
1 810 PHE n 
1 811 GLY n 
1 812 ALA n 
1 813 GLY n 
1 814 PHE n 
1 815 PHE n 
1 816 SER n 
1 817 ASN n 
1 818 LYS n 
1 819 TYR n 
1 820 VAL n 
1 821 ILE n 
1 822 GLY n 
1 823 ALA n 
1 824 VAL n 
1 825 LEU n 
1 826 LEU n 
1 827 CYS n 
1 828 PHE n 
1 829 VAL n 
1 830 LEU n 
1 831 TYR n 
1 832 GLY n 
1 833 ILE n 
1 834 THR n 
1 835 VAL n 
1 836 LEU n 
1 837 PRO n 
1 838 GLY n 
1 839 ALA n 
1 840 ARG n 
1 841 GLU n 
1 842 ILE n 
1 843 PHE n 
1 844 SER n 
1 845 ILE n 
1 846 PRO n 
1 847 ALA n 
1 848 SER n 
1 849 PHE n 
1 850 GLY n 
1 851 LEU n 
1 852 HIS n 
1 853 GLU n 
1 854 TRP n 
1 855 SER n 
1 856 ILE n 
1 857 ALA n 
1 858 ALA n 
1 859 GLY n 
1 860 LEU n 
1 861 ALA n 
1 862 LEU n 
1 863 ALA n 
1 864 ALA n 
1 865 VAL n 
1 866 VAL n 
1 867 MET n 
1 868 MET n 
1 869 GLU n 
1 870 ILE n 
1 871 ILE n 
1 872 LYS n 
1 873 VAL n 
1 874 VAL n 
1 875 GLN n 
1 876 ASN n 
1 877 LYS n 
1 878 PHE n 
1 879 PHE n 
1 880 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   880 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 lmo0841 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Listeria monocytogenes' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1639 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CA  non-polymer         . 'CALCIUM ION'   ? 'Ca 2'           40.078  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   GLU 2   2   2   GLU GLU A . n 
A 1 3   ILE 3   3   3   ILE ILE A . n 
A 1 4   TYR 4   4   4   TYR TYR A . n 
A 1 5   ARG 5   5   5   ARG ARG A . n 
A 1 6   LYS 6   6   6   LYS LYS A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   ALA 8   8   8   ALA ALA A . n 
A 1 9   ALA 9   9   9   ALA ALA A . n 
A 1 10  GLU 10  10  10  GLU GLU A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  PHE 12  12  12  PHE PHE A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  GLN 14  14  14  GLN GLN A . n 
A 1 15  LEU 15  15  15  LEU LEU A . n 
A 1 16  GLU 16  16  16  GLU GLU A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  THR 18  18  18  THR THR A . n 
A 1 19  GLU 19  19  ?   ?   ?   A . n 
A 1 20  LYS 20  20  ?   ?   ?   A . n 
A 1 21  GLY 21  21  ?   ?   ?   A . n 
A 1 22  LEU 22  22  ?   ?   ?   A . n 
A 1 23  THR 23  23  ?   ?   ?   A . n 
A 1 24  THR 24  24  ?   ?   ?   A . n 
A 1 25  SER 25  25  ?   ?   ?   A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  VAL 27  27  27  VAL VAL A . n 
A 1 28  THR 28  28  28  THR THR A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  ARG 30  30  30  ARG ARG A . n 
A 1 31  GLN 31  31  31  GLN GLN A . n 
A 1 32  GLU 32  32  32  GLU GLU A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  ASN 37  37  37  ASN ASN A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  LEU 39  39  ?   ?   ?   A . n 
A 1 40  LYS 40  40  ?   ?   ?   A . n 
A 1 41  ASN 41  41  ?   ?   ?   A . n 
A 1 42  LYS 42  42  ?   ?   ?   A . n 
A 1 43  LYS 43  43  ?   ?   ?   A . n 
A 1 44  LYS 44  44  ?   ?   ?   A . n 
A 1 45  ASP 45  45  45  ASP ASP A . n 
A 1 46  PRO 46  46  46  PRO PRO A . n 
A 1 47  LEU 47  47  47  LEU LEU A . n 
A 1 48  TRP 48  48  48  TRP TRP A . n 
A 1 49  LYS 49  49  49  LYS LYS A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  PHE 51  51  51  PHE PHE A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  GLU 53  53  53  GLU GLU A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  PHE 55  55  55  PHE PHE A . n 
A 1 56  LYS 56  56  56  LYS LYS A . n 
A 1 57  ASP 57  57  57  ASP ASP A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  MET 59  59  59  MET MET A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  ILE 61  61  61  ILE ILE A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  LEU 63  63  63  LEU LEU A . n 
A 1 64  VAL 64  64  64  VAL VAL A . n 
A 1 65  ILE 65  65  65  ILE ILE A . n 
A 1 66  ALA 66  66  66  ALA ALA A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  VAL 69  69  69  VAL VAL A . n 
A 1 70  GLN 70  70  70  GLN GLN A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  ILE 82  82  82  ILE ILE A . n 
A 1 83  PHE 83  83  83  PHE PHE A . n 
A 1 84  LEU 84  84  84  LEU LEU A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  VAL 88  88  88  VAL VAL A . n 
A 1 89  ASN 89  89  89  ASN ASN A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  ILE 91  91  91  ILE ILE A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  SER 93  93  93  SER SER A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  GLN 96  96  96  GLN GLN A . n 
A 1 97  THR 97  97  97  THR THR A . n 
A 1 98  ARG 98  98  98  ARG ARG A . n 
A 1 99  LYS 99  99  99  LYS LYS A . n 
A 1 100 ALA 100 100 100 ALA ALA A . n 
A 1 101 GLU 101 101 101 GLU GLU A . n 
A 1 102 SER 102 102 102 SER SER A . n 
A 1 103 SER 103 103 103 SER SER A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 SER 111 111 111 SER SER A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 PRO 113 113 113 PRO PRO A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 VAL 117 117 117 VAL VAL A . n 
A 1 118 ILE 118 118 118 ILE ILE A . n 
A 1 119 ARG 119 119 119 ARG ARG A . n 
A 1 120 ASP 120 120 120 ASP ASP A . n 
A 1 121 GLY 121 121 121 GLY GLY A . n 
A 1 122 SER 122 122 122 SER SER A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 GLN 124 124 124 GLN GLN A . n 
A 1 125 SER 125 125 125 SER SER A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 HIS 127 127 127 HIS HIS A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 ARG 129 129 129 ARG ARG A . n 
A 1 130 GLU 130 130 130 GLU GLU A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 VAL 137 137 137 VAL VAL A . n 
A 1 138 ILE 138 138 138 ILE ILE A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 ALA 141 141 141 ALA ALA A . n 
A 1 142 GLY 142 142 142 GLY GLY A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 PHE 144 144 144 PHE PHE A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 PRO 146 146 146 PRO PRO A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 ASP 148 148 148 ASP ASP A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 PHE 152 152 152 PHE PHE A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 SER 156 156 156 SER SER A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 LYS 158 158 158 LYS LYS A . n 
A 1 159 ILE 159 159 159 ILE ILE A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 GLU 161 161 161 GLU GLU A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 MET 163 163 163 MET MET A . n 
A 1 164 LEU 164 164 164 LEU LEU A . n 
A 1 165 THR 165 165 165 THR THR A . n 
A 1 166 GLY 166 166 166 GLY GLY A . n 
A 1 167 GLU 167 167 167 GLU GLU A . n 
A 1 168 SER 168 168 168 SER SER A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 GLU 172 172 172 GLU GLU A . n 
A 1 173 LYS 173 173 173 LYS LYS A . n 
A 1 174 TYR 174 174 174 TYR TYR A . n 
A 1 175 ILE 175 175 175 ILE ILE A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 THR 177 177 177 THR THR A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 PRO 179 179 179 PRO PRO A . n 
A 1 180 ASP 180 180 180 ASP ASP A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 ASP 186 186 186 ASP ASP A . n 
A 1 187 ARG 187 187 187 ARG ARG A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 ASN 189 189 189 ASN ASN A . n 
A 1 190 MET 190 190 190 MET MET A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 PHE 192 192 192 PHE PHE A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 SER 195 195 195 SER SER A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 TYR 199 199 199 TYR TYR A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 ARG 201 201 201 ARG ARG A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 MET 203 203 203 MET MET A . n 
A 1 204 PHE 204 204 204 PHE PHE A . n 
A 1 205 VAL 205 205 205 VAL VAL A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 THR 207 207 207 THR THR A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 THR 209 209 209 THR THR A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 SER 211 211 211 SER SER A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 LYS 217 217 217 LYS LYS A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 ALA 219 219 ?   ?   ?   A . n 
A 1 220 GLY 220 220 ?   ?   ?   A . n 
A 1 221 LEU 221 221 ?   ?   ?   A . n 
A 1 222 LEU 222 222 ?   ?   ?   A . n 
A 1 223 GLU 223 223 ?   ?   ?   A . n 
A 1 224 THR 224 224 ?   ?   ?   A . n 
A 1 225 ALA 225 225 ?   ?   ?   A . n 
A 1 226 GLU 226 226 ?   ?   ?   A . n 
A 1 227 ALA 227 227 ?   ?   ?   A . n 
A 1 228 LYS 228 228 ?   ?   ?   A . n 
A 1 229 GLN 229 229 229 GLN GLN A . n 
A 1 230 THR 230 230 230 THR THR A . n 
A 1 231 PRO 231 231 231 PRO PRO A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 GLN 233 233 233 GLN GLN A . n 
A 1 234 ARG 234 234 234 ARG ARG A . n 
A 1 235 LYS 235 235 235 LYS LYS A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 GLU 237 237 237 GLU GLU A . n 
A 1 238 SER 238 238 238 SER SER A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 LYS 241 241 241 LYS LYS A . n 
A 1 242 LYS 242 242 242 LYS LYS A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 GLY 244 244 244 GLY GLY A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 GLY 246 246 246 GLY GLY A . n 
A 1 247 ILE 247 247 247 ILE ILE A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 CYS 251 251 251 CYS CYS A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 PHE 255 255 255 PHE PHE A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 VAL 257 257 257 VAL VAL A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 ALA 259 259 259 ALA ALA A . n 
A 1 260 GLY 260 260 260 GLY GLY A . n 
A 1 261 ARG 261 261 261 ARG ARG A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 LEU 264 264 264 LEU LEU A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 ASP 266 266 266 ASP ASP A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 SER 268 268 268 SER SER A . n 
A 1 269 ALA 269 269 269 ALA ALA A . n 
A 1 270 ASP 270 270 270 ASP ASP A . n 
A 1 271 MET 271 271 271 MET MET A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 THR 273 273 273 THR THR A . n 
A 1 274 ALA 274 274 274 ALA ALA A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 ASN 277 277 277 ASN ASN A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 MET 280 280 280 MET MET A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 VAL 283 283 283 VAL VAL A . n 
A 1 284 ALA 284 284 284 ALA ALA A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 ALA 286 286 286 ALA ALA A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 PRO 291 291 291 PRO PRO A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 SER 296 296 296 SER SER A . n 
A 1 297 ILE 297 297 297 ILE ILE A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 THR 299 299 299 THR THR A . n 
A 1 300 ILE 300 300 300 ILE ILE A . n 
A 1 301 VAL 301 301 301 VAL VAL A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 THR 306 306 306 THR THR A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 MET 309 309 309 MET MET A . n 
A 1 310 ALA 310 310 310 ALA ALA A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 GLN 312 312 312 GLN GLN A . n 
A 1 313 HIS 313 313 313 HIS HIS A . n 
A 1 314 ALA 314 314 314 ALA ALA A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 ILE 316 316 316 ILE ILE A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 PRO 320 320 320 PRO PRO A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 GLU 323 323 323 GLU GLU A . n 
A 1 324 THR 324 324 324 THR THR A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 THR 328 328 328 THR THR A . n 
A 1 329 SER 329 329 329 SER SER A . n 
A 1 330 VAL 330 330 330 VAL VAL A . n 
A 1 331 ILE 331 331 331 ILE ILE A . n 
A 1 332 CYS 332 332 332 CYS CYS A . n 
A 1 333 THR 333 333 333 THR THR A . n 
A 1 334 ASP 334 334 334 ASP ASP A . n 
A 1 335 LYS 335 335 335 LYS LYS A . n 
A 1 336 THR 336 336 336 THR THR A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 THR 338 338 338 THR THR A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 GLN 341 341 341 GLN GLN A . n 
A 1 342 ASN 342 342 342 ASN ASN A . n 
A 1 343 LYS 343 343 343 LYS LYS A . n 
A 1 344 MET 344 344 344 MET MET A . n 
A 1 345 THR 345 345 345 THR THR A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 VAL 347 347 347 VAL VAL A . n 
A 1 348 ASP 348 348 348 ASP ASP A . n 
A 1 349 TYR 349 349 349 TYR TYR A . n 
A 1 350 TYR 350 350 350 TYR TYR A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 PRO 352 352 352 PRO PRO A . n 
A 1 353 ASP 353 353 353 ASP ASP A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 THR 355 355 355 THR THR A . n 
A 1 356 LYS 356 356 356 LYS LYS A . n 
A 1 357 GLU 357 357 357 GLU GLU A . n 
A 1 358 ASN 358 358 358 ASN ASN A . n 
A 1 359 PHE 359 359 359 PHE PHE A . n 
A 1 360 PRO 360 360 360 PRO PRO A . n 
A 1 361 GLU 361 361 361 GLU GLU A . n 
A 1 362 SER 362 362 362 SER SER A . n 
A 1 363 PRO 363 363 363 PRO PRO A . n 
A 1 364 GLU 364 364 364 GLU GLU A . n 
A 1 365 ASN 365 365 365 ASN ASN A . n 
A 1 366 TRP 366 366 366 TRP TRP A . n 
A 1 367 SER 367 367 367 SER SER A . n 
A 1 368 GLU 368 368 368 GLU GLU A . n 
A 1 369 GLY 369 369 369 GLY GLY A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 ARG 372 372 372 ARG ARG A . n 
A 1 373 LEU 373 373 373 LEU LEU A . n 
A 1 374 ILE 374 374 374 ILE ILE A . n 
A 1 375 HIS 375 375 375 HIS HIS A . n 
A 1 376 ILE 376 376 376 ILE ILE A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 VAL 378 378 378 VAL VAL A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 CYS 380 380 380 CYS CYS A . n 
A 1 381 ASN 381 381 381 ASN ASN A . n 
A 1 382 ASP 382 382 382 ASP ASP A . n 
A 1 383 SER 383 383 383 SER SER A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 ILE 385 385 385 ILE ILE A . n 
A 1 386 ASN 386 386 386 ASN ASN A . n 
A 1 387 SER 387 387 387 SER SER A . n 
A 1 388 GLU 388 388 388 GLU GLU A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 LYS 390 390 390 LYS LYS A . n 
A 1 391 GLU 391 391 391 GLU GLU A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 GLY 393 393 393 GLY GLY A . n 
A 1 394 ASP 394 394 394 ASP ASP A . n 
A 1 395 PRO 395 395 395 PRO PRO A . n 
A 1 396 THR 396 396 396 THR THR A . n 
A 1 397 GLU 397 397 397 GLU GLU A . n 
A 1 398 VAL 398 398 398 VAL VAL A . n 
A 1 399 ALA 399 399 399 ALA ALA A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 ILE 401 401 401 ILE ILE A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 PHE 403 403 403 PHE PHE A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 ASN 405 405 405 ASN ASN A . n 
A 1 406 LYS 406 406 406 LYS LYS A . n 
A 1 407 ASN 407 407 407 ASN ASN A . n 
A 1 408 ASN 408 408 408 ASN ASN A . n 
A 1 409 GLN 409 409 409 GLN GLN A . n 
A 1 410 ASP 410 410 410 ASP ASP A . n 
A 1 411 TYR 411 411 411 TYR TYR A . n 
A 1 412 ASN 412 412 412 ASN ASN A . n 
A 1 413 GLU 413 413 413 GLU GLU A . n 
A 1 414 ILE 414 414 414 ILE ILE A . n 
A 1 415 ARG 415 415 415 ARG ARG A . n 
A 1 416 GLU 416 416 416 GLU GLU A . n 
A 1 417 LYS 417 417 417 LYS LYS A . n 
A 1 418 PHE 418 418 418 PHE PHE A . n 
A 1 419 ILE 419 419 419 ILE ILE A . n 
A 1 420 ARG 420 420 420 ARG ARG A . n 
A 1 421 GLU 421 421 421 GLU GLU A . n 
A 1 422 GLY 422 422 422 GLY GLY A . n 
A 1 423 GLU 423 423 423 GLU GLU A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 PRO 425 425 425 PRO PRO A . n 
A 1 426 PHE 426 426 426 PHE PHE A . n 
A 1 427 ASP 427 427 427 ASP ASP A . n 
A 1 428 SER 428 428 428 SER SER A . n 
A 1 429 ASP 429 429 429 ASP ASP A . n 
A 1 430 ARG 430 430 430 ARG ARG A . n 
A 1 431 LYS 431 431 431 LYS LYS A . n 
A 1 432 LEU 432 432 432 LEU LEU A . n 
A 1 433 MET 433 433 433 MET MET A . n 
A 1 434 SER 434 434 434 SER SER A . n 
A 1 435 THR 435 435 435 THR THR A . n 
A 1 436 LEU 436 436 436 LEU LEU A . n 
A 1 437 HIS 437 437 437 HIS HIS A . n 
A 1 438 THR 438 438 438 THR THR A . n 
A 1 439 PHE 439 439 439 PHE PHE A . n 
A 1 440 ASN 440 440 440 ASN ASN A . n 
A 1 441 GLU 441 441 441 GLU GLU A . n 
A 1 442 ASN 442 442 442 ASN ASN A . n 
A 1 443 LYS 443 443 443 LYS LYS A . n 
A 1 444 ALA 444 444 444 ALA ALA A . n 
A 1 445 MET 445 445 445 MET MET A . n 
A 1 446 LEU 446 446 446 LEU LEU A . n 
A 1 447 THR 447 447 447 THR THR A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 GLY 449 449 449 GLY GLY A . n 
A 1 450 GLY 450 450 450 GLY GLY A . n 
A 1 451 PRO 451 451 451 PRO PRO A . n 
A 1 452 ASP 452 452 452 ASP ASP A . n 
A 1 453 VAL 453 453 453 VAL VAL A . n 
A 1 454 MET 454 454 454 MET MET A . n 
A 1 455 PHE 455 455 455 PHE PHE A . n 
A 1 456 ALA 456 456 456 ALA ALA A . n 
A 1 457 ARG 457 457 457 ARG ARG A . n 
A 1 458 CYS 458 458 458 CYS CYS A . n 
A 1 459 SER 459 459 459 SER SER A . n 
A 1 460 TYR 460 460 460 TYR TYR A . n 
A 1 461 VAL 461 461 461 VAL VAL A . n 
A 1 462 PHE 462 462 462 PHE PHE A . n 
A 1 463 LEU 463 463 463 LEU LEU A . n 
A 1 464 ASP 464 464 464 ASP ASP A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 GLU 466 466 466 GLU GLU A . n 
A 1 467 GLU 467 467 467 GLU GLU A . n 
A 1 468 LYS 468 468 468 LYS LYS A . n 
A 1 469 PRO 469 469 469 PRO PRO A . n 
A 1 470 MET 470 470 470 MET MET A . n 
A 1 471 THR 471 471 471 THR THR A . n 
A 1 472 GLU 472 472 472 GLU GLU A . n 
A 1 473 GLU 473 473 473 GLU GLU A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 ALA 476 476 476 ALA ALA A . n 
A 1 477 LYS 477 477 477 LYS LYS A . n 
A 1 478 LEU 478 478 478 LEU LEU A . n 
A 1 479 LYS 479 479 479 LYS LYS A . n 
A 1 480 GLU 480 480 480 GLU GLU A . n 
A 1 481 THR 481 481 481 THR THR A . n 
A 1 482 ASN 482 482 482 ASN ASN A . n 
A 1 483 GLU 483 483 483 GLU GLU A . n 
A 1 484 GLU 484 484 484 GLU GLU A . n 
A 1 485 PHE 485 485 485 PHE PHE A . n 
A 1 486 SER 486 486 486 SER SER A . n 
A 1 487 ASN 487 487 487 ASN ASN A . n 
A 1 488 GLN 488 488 488 GLN GLN A . n 
A 1 489 ALA 489 489 489 ALA ALA A . n 
A 1 490 LEU 490 490 490 LEU LEU A . n 
A 1 491 ARG 491 491 491 ARG ARG A . n 
A 1 492 VAL 492 492 492 VAL VAL A . n 
A 1 493 LEU 493 493 493 LEU LEU A . n 
A 1 494 ALA 494 494 494 ALA ALA A . n 
A 1 495 TYR 495 495 495 TYR TYR A . n 
A 1 496 GLY 496 496 496 GLY GLY A . n 
A 1 497 TYR 497 497 497 TYR TYR A . n 
A 1 498 LYS 498 498 498 LYS LYS A . n 
A 1 499 ARG 499 499 499 ARG ARG A . n 
A 1 500 MET 500 500 500 MET MET A . n 
A 1 501 PRO 501 501 501 PRO PRO A . n 
A 1 502 ALA 502 502 502 ALA ALA A . n 
A 1 503 ASP 503 503 503 ASP ASP A . n 
A 1 504 THR 504 504 504 THR THR A . n 
A 1 505 THR 505 505 505 THR THR A . n 
A 1 506 GLU 506 506 506 GLU GLU A . n 
A 1 507 LEU 507 507 507 LEU LEU A . n 
A 1 508 LYS 508 508 508 LYS LYS A . n 
A 1 509 LEU 509 509 509 LEU LEU A . n 
A 1 510 GLU 510 510 510 GLU GLU A . n 
A 1 511 ASP 511 511 511 ASP ASP A . n 
A 1 512 GLU 512 512 512 GLU GLU A . n 
A 1 513 GLN 513 513 513 GLN GLN A . n 
A 1 514 ASP 514 514 514 ASP ASP A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 VAL 516 516 516 VAL VAL A . n 
A 1 517 LEU 517 517 517 LEU LEU A . n 
A 1 518 VAL 518 518 518 VAL VAL A . n 
A 1 519 GLY 519 519 519 GLY GLY A . n 
A 1 520 LEU 520 520 520 LEU LEU A . n 
A 1 521 THR 521 521 521 THR THR A . n 
A 1 522 ALA 522 522 522 ALA ALA A . n 
A 1 523 MET 523 523 523 MET MET A . n 
A 1 524 ILE 524 524 524 ILE ILE A . n 
A 1 525 ASP 525 525 525 ASP ASP A . n 
A 1 526 PRO 526 526 526 PRO PRO A . n 
A 1 527 PRO 527 527 527 PRO PRO A . n 
A 1 528 ARG 528 528 528 ARG ARG A . n 
A 1 529 GLU 529 529 529 GLU GLU A . n 
A 1 530 ALA 530 530 530 ALA ALA A . n 
A 1 531 VAL 531 531 531 VAL VAL A . n 
A 1 532 TYR 532 532 532 TYR TYR A . n 
A 1 533 ALA 533 533 533 ALA ALA A . n 
A 1 534 SER 534 534 534 SER SER A . n 
A 1 535 ILE 535 535 535 ILE ILE A . n 
A 1 536 GLU 536 536 536 GLU GLU A . n 
A 1 537 GLU 537 537 537 GLU GLU A . n 
A 1 538 SER 538 538 538 SER SER A . n 
A 1 539 LYS 539 539 539 LYS LYS A . n 
A 1 540 LYS 540 540 540 LYS LYS A . n 
A 1 541 ALA 541 541 541 ALA ALA A . n 
A 1 542 GLY 542 542 542 GLY GLY A . n 
A 1 543 ILE 543 543 543 ILE ILE A . n 
A 1 544 ARG 544 544 544 ARG ARG A . n 
A 1 545 THR 545 545 545 THR THR A . n 
A 1 546 VAL 546 546 546 VAL VAL A . n 
A 1 547 MET 547 547 547 MET MET A . n 
A 1 548 ILE 548 548 548 ILE ILE A . n 
A 1 549 THR 549 549 549 THR THR A . n 
A 1 550 GLY 550 550 550 GLY GLY A . n 
A 1 551 ASP 551 551 551 ASP ASP A . n 
A 1 552 HIS 552 552 552 HIS HIS A . n 
A 1 553 LYS 553 553 553 LYS LYS A . n 
A 1 554 THR 554 554 554 THR THR A . n 
A 1 555 THR 555 555 555 THR THR A . n 
A 1 556 ALA 556 556 556 ALA ALA A . n 
A 1 557 GLN 557 557 557 GLN GLN A . n 
A 1 558 ALA 558 558 558 ALA ALA A . n 
A 1 559 ILE 559 559 559 ILE ILE A . n 
A 1 560 GLY 560 560 560 GLY GLY A . n 
A 1 561 ARG 561 561 561 ARG ARG A . n 
A 1 562 ASP 562 562 562 ASP ASP A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 GLY 564 564 564 GLY GLY A . n 
A 1 565 LEU 565 565 565 LEU LEU A . n 
A 1 566 MET 566 566 566 MET MET A . n 
A 1 567 ASP 567 567 567 ASP ASP A . n 
A 1 568 ALA 568 568 568 ALA ALA A . n 
A 1 569 ASP 569 569 569 ASP ASP A . n 
A 1 570 ASP 570 570 570 ASP ASP A . n 
A 1 571 ILE 571 571 571 ILE ILE A . n 
A 1 572 ALA 572 572 572 ALA ALA A . n 
A 1 573 LEU 573 573 573 LEU LEU A . n 
A 1 574 THR 574 574 574 THR THR A . n 
A 1 575 GLY 575 575 575 GLY GLY A . n 
A 1 576 GLN 576 576 576 GLN GLN A . n 
A 1 577 GLU 577 577 577 GLU GLU A . n 
A 1 578 LEU 578 578 578 LEU LEU A . n 
A 1 579 ASP 579 579 579 ASP ASP A . n 
A 1 580 ALA 580 580 580 ALA ALA A . n 
A 1 581 MET 581 581 581 MET MET A . n 
A 1 582 PRO 582 582 582 PRO PRO A . n 
A 1 583 GLU 583 583 583 GLU GLU A . n 
A 1 584 GLU 584 584 584 GLU GLU A . n 
A 1 585 GLU 585 585 585 GLU GLU A . n 
A 1 586 LEU 586 586 586 LEU LEU A . n 
A 1 587 ASP 587 587 587 ASP ASP A . n 
A 1 588 LYS 588 588 588 LYS LYS A . n 
A 1 589 LYS 589 589 589 LYS LYS A . n 
A 1 590 LEU 590 590 590 LEU LEU A . n 
A 1 591 GLU 591 591 591 GLU GLU A . n 
A 1 592 HIS 592 592 592 HIS HIS A . n 
A 1 593 ILE 593 593 593 ILE ILE A . n 
A 1 594 ALA 594 594 594 ALA ALA A . n 
A 1 595 VAL 595 595 595 VAL VAL A . n 
A 1 596 TYR 596 596 596 TYR TYR A . n 
A 1 597 ALA 597 597 597 ALA ALA A . n 
A 1 598 ARG 598 598 598 ARG ARG A . n 
A 1 599 VAL 599 599 599 VAL VAL A . n 
A 1 600 SER 600 600 600 SER SER A . n 
A 1 601 PRO 601 601 601 PRO PRO A . n 
A 1 602 GLU 602 602 602 GLU GLU A . n 
A 1 603 ASN 603 603 603 ASN ASN A . n 
A 1 604 LYS 604 604 604 LYS LYS A . n 
A 1 605 ILE 605 605 605 ILE ILE A . n 
A 1 606 ARG 606 606 606 ARG ARG A . n 
A 1 607 ILE 607 607 607 ILE ILE A . n 
A 1 608 VAL 608 608 608 VAL VAL A . n 
A 1 609 LYS 609 609 609 LYS LYS A . n 
A 1 610 ALA 610 610 610 ALA ALA A . n 
A 1 611 TRP 611 611 611 TRP TRP A . n 
A 1 612 GLN 612 612 612 GLN GLN A . n 
A 1 613 LYS 613 613 613 LYS LYS A . n 
A 1 614 LYS 614 614 614 LYS LYS A . n 
A 1 615 GLY 615 615 615 GLY GLY A . n 
A 1 616 LYS 616 616 616 LYS LYS A . n 
A 1 617 ILE 617 617 617 ILE ILE A . n 
A 1 618 THR 618 618 618 THR THR A . n 
A 1 619 ALA 619 619 619 ALA ALA A . n 
A 1 620 MET 620 620 620 MET MET A . n 
A 1 621 THR 621 621 621 THR THR A . n 
A 1 622 GLY 622 622 622 GLY GLY A . n 
A 1 623 ASP 623 623 623 ASP ASP A . n 
A 1 624 GLY 624 624 624 GLY GLY A . n 
A 1 625 VAL 625 625 625 VAL VAL A . n 
A 1 626 ASN 626 626 626 ASN ASN A . n 
A 1 627 ASP 627 627 627 ASP ASP A . n 
A 1 628 ALA 628 628 628 ALA ALA A . n 
A 1 629 PRO 629 629 629 PRO PRO A . n 
A 1 630 ALA 630 630 630 ALA ALA A . n 
A 1 631 LEU 631 631 631 LEU LEU A . n 
A 1 632 LYS 632 632 632 LYS LYS A . n 
A 1 633 GLN 633 633 633 GLN GLN A . n 
A 1 634 ALA 634 634 634 ALA ALA A . n 
A 1 635 ASP 635 635 635 ASP ASP A . n 
A 1 636 ILE 636 636 636 ILE ILE A . n 
A 1 637 GLY 637 637 637 GLY GLY A . n 
A 1 638 VAL 638 638 638 VAL VAL A . n 
A 1 639 ALA 639 639 639 ALA ALA A . n 
A 1 640 MET 640 640 640 MET MET A . n 
A 1 641 GLY 641 641 641 GLY GLY A . n 
A 1 642 SER 642 642 642 SER SER A . n 
A 1 643 GLY 643 643 643 GLY GLY A . n 
A 1 644 THR 644 644 644 THR THR A . n 
A 1 645 ASP 645 645 645 ASP ASP A . n 
A 1 646 VAL 646 646 646 VAL VAL A . n 
A 1 647 ALA 647 647 647 ALA ALA A . n 
A 1 648 LYS 648 648 648 LYS LYS A . n 
A 1 649 ASP 649 649 649 ASP ASP A . n 
A 1 650 SER 650 650 650 SER SER A . n 
A 1 651 ALA 651 651 651 ALA ALA A . n 
A 1 652 ALA 652 652 652 ALA ALA A . n 
A 1 653 MET 653 653 653 MET MET A . n 
A 1 654 ILE 654 654 654 ILE ILE A . n 
A 1 655 LEU 655 655 655 LEU LEU A . n 
A 1 656 THR 656 656 656 THR THR A . n 
A 1 657 ASP 657 657 657 ASP ASP A . n 
A 1 658 ASP 658 658 658 ASP ASP A . n 
A 1 659 ASN 659 659 659 ASN ASN A . n 
A 1 660 PHE 660 660 660 PHE PHE A . n 
A 1 661 VAL 661 661 661 VAL VAL A . n 
A 1 662 SER 662 662 662 SER SER A . n 
A 1 663 ILE 663 663 663 ILE ILE A . n 
A 1 664 VAL 664 664 664 VAL VAL A . n 
A 1 665 ASP 665 665 665 ASP ASP A . n 
A 1 666 ALA 666 666 666 ALA ALA A . n 
A 1 667 VAL 667 667 667 VAL VAL A . n 
A 1 668 GLY 668 668 668 GLY GLY A . n 
A 1 669 VAL 669 669 669 VAL VAL A . n 
A 1 670 GLY 670 670 670 GLY GLY A . n 
A 1 671 ARG 671 671 671 ARG ARG A . n 
A 1 672 THR 672 672 672 THR THR A . n 
A 1 673 VAL 673 673 673 VAL VAL A . n 
A 1 674 PHE 674 674 674 PHE PHE A . n 
A 1 675 ASP 675 675 675 ASP ASP A . n 
A 1 676 ASN 676 676 676 ASN ASN A . n 
A 1 677 ILE 677 677 677 ILE ILE A . n 
A 1 678 LYS 678 678 678 LYS LYS A . n 
A 1 679 LYS 679 679 679 LYS LYS A . n 
A 1 680 SER 680 680 680 SER SER A . n 
A 1 681 ILE 681 681 681 ILE ILE A . n 
A 1 682 ALA 682 682 682 ALA ALA A . n 
A 1 683 TYR 683 683 683 TYR TYR A . n 
A 1 684 LEU 684 684 684 LEU LEU A . n 
A 1 685 PHE 685 685 685 PHE PHE A . n 
A 1 686 ALA 686 686 686 ALA ALA A . n 
A 1 687 GLY 687 687 687 GLY GLY A . n 
A 1 688 ASN 688 688 688 ASN ASN A . n 
A 1 689 LEU 689 689 689 LEU LEU A . n 
A 1 690 GLY 690 690 690 GLY GLY A . n 
A 1 691 ALA 691 691 691 ALA ALA A . n 
A 1 692 ILE 692 692 692 ILE ILE A . n 
A 1 693 ILE 693 693 693 ILE ILE A . n 
A 1 694 ALA 694 694 694 ALA ALA A . n 
A 1 695 ILE 695 695 695 ILE ILE A . n 
A 1 696 LEU 696 696 696 LEU LEU A . n 
A 1 697 PHE 697 697 697 PHE PHE A . n 
A 1 698 ALA 698 698 698 ALA ALA A . n 
A 1 699 LEU 699 699 699 LEU LEU A . n 
A 1 700 VAL 700 700 700 VAL VAL A . n 
A 1 701 LEU 701 701 701 LEU LEU A . n 
A 1 702 ASP 702 702 702 ASP ASP A . n 
A 1 703 TRP 703 703 703 TRP TRP A . n 
A 1 704 ILE 704 704 704 ILE ILE A . n 
A 1 705 ASN 705 705 705 ASN ASN A . n 
A 1 706 PRO 706 706 706 PRO PRO A . n 
A 1 707 PHE 707 707 707 PHE PHE A . n 
A 1 708 THR 708 708 708 THR THR A . n 
A 1 709 ALA 709 709 709 ALA ALA A . n 
A 1 710 LEU 710 710 710 LEU LEU A . n 
A 1 711 GLN 711 711 711 GLN GLN A . n 
A 1 712 LEU 712 712 712 LEU LEU A . n 
A 1 713 LEU 713 713 713 LEU LEU A . n 
A 1 714 PHE 714 714 714 PHE PHE A . n 
A 1 715 ILE 715 715 715 ILE ILE A . n 
A 1 716 ASN 716 716 716 ASN ASN A . n 
A 1 717 LEU 717 717 717 LEU LEU A . n 
A 1 718 VAL 718 718 718 VAL VAL A . n 
A 1 719 ASN 719 719 719 ASN ASN A . n 
A 1 720 ASP 720 720 720 ASP ASP A . n 
A 1 721 SER 721 721 721 SER SER A . n 
A 1 722 LEU 722 722 722 LEU LEU A . n 
A 1 723 PRO 723 723 723 PRO PRO A . n 
A 1 724 ALA 724 724 724 ALA ALA A . n 
A 1 725 ILE 725 725 725 ILE ILE A . n 
A 1 726 ALA 726 726 726 ALA ALA A . n 
A 1 727 LEU 727 727 727 LEU LEU A . n 
A 1 728 GLY 728 728 728 GLY GLY A . n 
A 1 729 MET 729 729 729 MET MET A . n 
A 1 730 GLU 730 730 730 GLU GLU A . n 
A 1 731 LYS 731 731 731 LYS LYS A . n 
A 1 732 ALA 732 732 732 ALA ALA A . n 
A 1 733 GLU 733 733 733 GLU GLU A . n 
A 1 734 PRO 734 734 734 PRO PRO A . n 
A 1 735 ASP 735 735 735 ASP ASP A . n 
A 1 736 VAL 736 736 736 VAL VAL A . n 
A 1 737 MET 737 737 737 MET MET A . n 
A 1 738 LYS 738 738 738 LYS LYS A . n 
A 1 739 ARG 739 739 739 ARG ARG A . n 
A 1 740 LYS 740 740 740 LYS LYS A . n 
A 1 741 PRO 741 741 741 PRO PRO A . n 
A 1 742 ARG 742 742 742 ARG ARG A . n 
A 1 743 ASP 743 743 743 ASP ASP A . n 
A 1 744 ILE 744 744 744 ILE ILE A . n 
A 1 745 ASN 745 745 745 ASN ASN A . n 
A 1 746 GLU 746 746 746 GLU GLU A . n 
A 1 747 GLY 747 747 747 GLY GLY A . n 
A 1 748 ILE 748 748 748 ILE ILE A . n 
A 1 749 PHE 749 749 749 PHE PHE A . n 
A 1 750 ALA 750 750 750 ALA ALA A . n 
A 1 751 GLY 751 751 751 GLY GLY A . n 
A 1 752 GLY 752 752 752 GLY GLY A . n 
A 1 753 THR 753 753 753 THR THR A . n 
A 1 754 MET 754 754 754 MET MET A . n 
A 1 755 ARG 755 755 755 ARG ARG A . n 
A 1 756 ALA 756 756 756 ALA ALA A . n 
A 1 757 VAL 757 757 757 VAL VAL A . n 
A 1 758 ILE 758 758 758 ILE ILE A . n 
A 1 759 SER 759 759 759 SER SER A . n 
A 1 760 ARG 760 760 760 ARG ARG A . n 
A 1 761 GLY 761 761 761 GLY GLY A . n 
A 1 762 VAL 762 762 762 VAL VAL A . n 
A 1 763 LEU 763 763 763 LEU LEU A . n 
A 1 764 ILE 764 764 764 ILE ILE A . n 
A 1 765 GLY 765 765 765 GLY GLY A . n 
A 1 766 ILE 766 766 766 ILE ILE A . n 
A 1 767 ALA 767 767 767 ALA ALA A . n 
A 1 768 VAL 768 768 768 VAL VAL A . n 
A 1 769 ILE 769 769 769 ILE ILE A . n 
A 1 770 ILE 770 770 770 ILE ILE A . n 
A 1 771 SER 771 771 771 SER SER A . n 
A 1 772 GLN 772 772 772 GLN GLN A . n 
A 1 773 TYR 773 773 773 TYR TYR A . n 
A 1 774 ILE 774 774 774 ILE ILE A . n 
A 1 775 GLY 775 775 775 GLY GLY A . n 
A 1 776 MET 776 776 776 MET MET A . n 
A 1 777 GLN 777 777 777 GLN GLN A . n 
A 1 778 ILE 778 778 778 ILE ILE A . n 
A 1 779 SER 779 779 779 SER SER A . n 
A 1 780 PRO 780 780 780 PRO PRO A . n 
A 1 781 GLU 781 781 781 GLU GLU A . n 
A 1 782 MET 782 782 782 MET MET A . n 
A 1 783 SER 783 783 783 SER SER A . n 
A 1 784 VAL 784 784 784 VAL VAL A . n 
A 1 785 ALA 785 785 785 ALA ALA A . n 
A 1 786 MET 786 786 786 MET MET A . n 
A 1 787 ALA 787 787 787 ALA ALA A . n 
A 1 788 PHE 788 788 788 PHE PHE A . n 
A 1 789 THR 789 789 789 THR THR A . n 
A 1 790 THR 790 790 790 THR THR A . n 
A 1 791 LEU 791 791 791 LEU LEU A . n 
A 1 792 ILE 792 792 792 ILE ILE A . n 
A 1 793 LEU 793 793 793 LEU LEU A . n 
A 1 794 ALA 794 794 794 ALA ALA A . n 
A 1 795 ARG 795 795 795 ARG ARG A . n 
A 1 796 THR 796 796 796 THR THR A . n 
A 1 797 LEU 797 797 797 LEU LEU A . n 
A 1 798 GLN 798 798 798 GLN GLN A . n 
A 1 799 THR 799 799 799 THR THR A . n 
A 1 800 PHE 800 800 800 PHE PHE A . n 
A 1 801 ALA 801 801 801 ALA ALA A . n 
A 1 802 ALA 802 802 802 ALA ALA A . n 
A 1 803 ARG 803 803 803 ARG ARG A . n 
A 1 804 SER 804 804 804 SER SER A . n 
A 1 805 ASN 805 805 805 ASN ASN A . n 
A 1 806 VAL 806 806 806 VAL VAL A . n 
A 1 807 GLN 807 807 807 GLN GLN A . n 
A 1 808 THR 808 808 808 THR THR A . n 
A 1 809 ALA 809 809 809 ALA ALA A . n 
A 1 810 PHE 810 810 810 PHE PHE A . n 
A 1 811 GLY 811 811 811 GLY GLY A . n 
A 1 812 ALA 812 812 812 ALA ALA A . n 
A 1 813 GLY 813 813 813 GLY GLY A . n 
A 1 814 PHE 814 814 814 PHE PHE A . n 
A 1 815 PHE 815 815 815 PHE PHE A . n 
A 1 816 SER 816 816 816 SER SER A . n 
A 1 817 ASN 817 817 817 ASN ASN A . n 
A 1 818 LYS 818 818 818 LYS LYS A . n 
A 1 819 TYR 819 819 819 TYR TYR A . n 
A 1 820 VAL 820 820 820 VAL VAL A . n 
A 1 821 ILE 821 821 821 ILE ILE A . n 
A 1 822 GLY 822 822 822 GLY GLY A . n 
A 1 823 ALA 823 823 823 ALA ALA A . n 
A 1 824 VAL 824 824 824 VAL VAL A . n 
A 1 825 LEU 825 825 825 LEU LEU A . n 
A 1 826 LEU 826 826 826 LEU LEU A . n 
A 1 827 CYS 827 827 827 CYS CYS A . n 
A 1 828 PHE 828 828 828 PHE PHE A . n 
A 1 829 VAL 829 829 829 VAL VAL A . n 
A 1 830 LEU 830 830 830 LEU LEU A . n 
A 1 831 TYR 831 831 831 TYR TYR A . n 
A 1 832 GLY 832 832 832 GLY GLY A . n 
A 1 833 ILE 833 833 833 ILE ILE A . n 
A 1 834 THR 834 834 834 THR THR A . n 
A 1 835 VAL 835 835 835 VAL VAL A . n 
A 1 836 LEU 836 836 836 LEU LEU A . n 
A 1 837 PRO 837 837 837 PRO PRO A . n 
A 1 838 GLY 838 838 838 GLY GLY A . n 
A 1 839 ALA 839 839 839 ALA ALA A . n 
A 1 840 ARG 840 840 840 ARG ARG A . n 
A 1 841 GLU 841 841 841 GLU GLU A . n 
A 1 842 ILE 842 842 842 ILE ILE A . n 
A 1 843 PHE 843 843 843 PHE PHE A . n 
A 1 844 SER 844 844 844 SER SER A . n 
A 1 845 ILE 845 845 845 ILE ILE A . n 
A 1 846 PRO 846 846 846 PRO PRO A . n 
A 1 847 ALA 847 847 847 ALA ALA A . n 
A 1 848 SER 848 848 848 SER SER A . n 
A 1 849 PHE 849 849 849 PHE PHE A . n 
A 1 850 GLY 850 850 850 GLY GLY A . n 
A 1 851 LEU 851 851 851 LEU LEU A . n 
A 1 852 HIS 852 852 852 HIS HIS A . n 
A 1 853 GLU 853 853 853 GLU GLU A . n 
A 1 854 TRP 854 854 854 TRP TRP A . n 
A 1 855 SER 855 855 855 SER SER A . n 
A 1 856 ILE 856 856 856 ILE ILE A . n 
A 1 857 ALA 857 857 857 ALA ALA A . n 
A 1 858 ALA 858 858 858 ALA ALA A . n 
A 1 859 GLY 859 859 859 GLY GLY A . n 
A 1 860 LEU 860 860 860 LEU LEU A . n 
A 1 861 ALA 861 861 861 ALA ALA A . n 
A 1 862 LEU 862 862 862 LEU LEU A . n 
A 1 863 ALA 863 863 863 ALA ALA A . n 
A 1 864 ALA 864 864 864 ALA ALA A . n 
A 1 865 VAL 865 865 865 VAL VAL A . n 
A 1 866 VAL 866 866 866 VAL VAL A . n 
A 1 867 MET 867 867 867 MET MET A . n 
A 1 868 MET 868 868 868 MET MET A . n 
A 1 869 GLU 869 869 869 GLU GLU A . n 
A 1 870 ILE 870 870 870 ILE ILE A . n 
A 1 871 ILE 871 871 871 ILE ILE A . n 
A 1 872 LYS 872 872 872 LYS LYS A . n 
A 1 873 VAL 873 873 873 VAL VAL A . n 
A 1 874 VAL 874 874 874 VAL VAL A . n 
A 1 875 GLN 875 875 875 GLN GLN A . n 
A 1 876 ASN 876 876 876 ASN ASN A . n 
A 1 877 LYS 877 877 877 LYS LYS A . n 
A 1 878 PHE 878 878 878 PHE PHE A . n 
A 1 879 PHE 879 879 879 PHE PHE A . n 
A 1 880 LYS 880 880 880 LYS LYS A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        CA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   CA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          CA 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     901 
_pdbx_nonpoly_scheme.auth_seq_num    901 
_pdbx_nonpoly_scheme.pdb_mon_id      CA 
_pdbx_nonpoly_scheme.auth_mon_id     CA 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A MET 500 ? CG  ? A MET 500 CG  
2  1 Y 1 A MET 500 ? SD  ? A MET 500 SD  
3  1 Y 1 A MET 500 ? CE  ? A MET 500 CE  
4  1 Y 1 A PRO 501 ? CG  ? A PRO 501 CG  
5  1 Y 1 A PRO 501 ? CD  ? A PRO 501 CD  
6  1 Y 1 A ASP 503 ? CG  ? A ASP 503 CG  
7  1 Y 1 A ASP 503 ? OD1 ? A ASP 503 OD1 
8  1 Y 1 A ASP 503 ? OD2 ? A ASP 503 OD2 
9  1 Y 1 A THR 504 ? OG1 ? A THR 504 OG1 
10 1 Y 1 A THR 504 ? CG2 ? A THR 504 CG2 
11 1 Y 1 A THR 505 ? OG1 ? A THR 505 OG1 
12 1 Y 1 A THR 505 ? CG2 ? A THR 505 CG2 
13 1 Y 1 A GLU 506 ? CG  ? A GLU 506 CG  
14 1 Y 1 A GLU 506 ? CD  ? A GLU 506 CD  
15 1 Y 1 A GLU 506 ? OE1 ? A GLU 506 OE1 
16 1 Y 1 A GLU 506 ? OE2 ? A GLU 506 OE2 
17 1 Y 1 A LEU 507 ? CG  ? A LEU 507 CG  
18 1 Y 1 A LEU 507 ? CD1 ? A LEU 507 CD1 
19 1 Y 1 A LEU 507 ? CD2 ? A LEU 507 CD2 
20 1 Y 1 A LYS 508 ? CG  ? A LYS 508 CG  
21 1 Y 1 A LYS 508 ? CD  ? A LYS 508 CD  
22 1 Y 1 A LYS 508 ? CE  ? A LYS 508 CE  
23 1 Y 1 A LYS 508 ? NZ  ? A LYS 508 NZ  
24 1 Y 1 A LEU 509 ? CG  ? A LEU 509 CG  
25 1 Y 1 A LEU 509 ? CD1 ? A LEU 509 CD1 
26 1 Y 1 A LEU 509 ? CD2 ? A LEU 509 CD2 
27 1 Y 1 A GLU 510 ? CG  ? A GLU 510 CG  
28 1 Y 1 A GLU 510 ? CD  ? A GLU 510 CD  
29 1 Y 1 A GLU 510 ? OE1 ? A GLU 510 OE1 
30 1 Y 1 A GLU 510 ? OE2 ? A GLU 510 OE2 
31 1 Y 1 A ASP 511 ? CG  ? A ASP 511 CG  
32 1 Y 1 A ASP 511 ? OD1 ? A ASP 511 OD1 
33 1 Y 1 A ASP 511 ? OD2 ? A ASP 511 OD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EVC 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EVC 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EVC 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9EVC 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 6601 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.801 ? 8933 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.191 ? 906  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.049 ? 1070 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1141 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9EVC 
_struct.title                        'CryoEM structure of LMCA1 in E1-Ca state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EVC 
_struct_keywords.text            'transporter, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    LMCA1_LISMO 
_struct_ref.pdbx_db_accession          Q8Y8Q5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;EIYRKSAAETFTQLEATEKGLTTSEVTKRQEKYGFNELKNKKKDPLWKLFLETFKDPMVIVLVIAALVQLVLGEVVESLI
IFLVLIVNSIISVVQTRKAESSLDALREMSAPVAKVIRDGSKQSIHARELVPGDVVILDAGDFVPADGRLFESGSLKIDE
GMLTGESEAVEKYIDTIPDEVGLGDRVNMVFSGSLVVYGRGMFVVTGTASETEIGKIAGLLETAEAKQTPLQRKLESFSK
KLGLGILALCVLIFAVEAGRVLLGDNSADMATAILNAFMFAVAVAVAAIPEALSSIVTIVLAVGTNKMAKQHAIIRKLPA
VETLGSTSVICTDKTGTLTQNKMTVVDYYLPDGTKENFPESPENWSEGERRLIHIAVLCNDSNINSEGKELGDPTEVALI
AFSNKNNQDYNEIREKFIREGEIPFDSDRKLMSTLHTFNENKAMLTKGGPDVMFARCSYVFLDGEEKPMTEEILAKLKET
NEEFSNQALRVLAYGYKRMPADTTELKLEDEQDIVLVGLTAMIDPPREAVYASIEESKKAGIRTVMITGDHKTTAQAIGR
DIGLMDADDIALTGQELDAMPEEELDKKLEHIAVYARVSPENKIRIVKAWQKKGKITAMTGDGVNDAPALKQADIGVAMG
SGTDVAKDSAAMILTDDNFVSIVDAVGVGRTVFDNIKKSIAYLFAGNLGAIIAILFALVLDWINPFTALQLLFINLVNDS
LPAIALGMEKAEPDVMKRKPRDINEGIFAGGTMRAVISRGVLIGIAVIISQYIGMQISPEMSVAMAFTTLILARTLQTFA
ARSNVQTAFGAGFFSNKYVIGAVLLCFVLYGITVLPGAREIFSIPASFGLHEWSIAAGLALAAVVMMEIIKVVQNKFFK
;
_struct_ref.pdbx_align_begin           2 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9EVC 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 2 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 880 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q8Y8Q5 
_struct_ref_seq.db_align_beg                  2 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  880 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       2 
_struct_ref_seq.pdbx_auth_seq_align_end       880 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9EVC 
_struct_ref_seq_dif.mon_id                       ALA 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      1 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   Q8Y8Q5 
_struct_ref_seq_dif.db_mon_id                    ? 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          ? 
_struct_ref_seq_dif.details                      'expression tag' 
_struct_ref_seq_dif.pdbx_auth_seq_num            1 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 0     ? 
1 MORE         0     ? 
1 'SSA (A^2)'  37270 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 7   ? LEU A 15  ? SER A 7   LEU A 15  1 ? 9  
HELX_P HELX_P2  AA2 VAL A 27  ? GLY A 35  ? VAL A 27  GLY A 35  1 ? 9  
HELX_P HELX_P3  AA3 PRO A 46  ? THR A 54  ? PRO A 46  THR A 54  1 ? 9  
HELX_P HELX_P4  AA4 ASP A 57  ? LEU A 73  ? ASP A 57  LEU A 73  1 ? 17 
HELX_P HELX_P5  AA5 GLU A 75  ? SER A 111 ? GLU A 75  SER A 111 1 ? 37 
HELX_P HELX_P6  AA6 THR A 213 ? ILE A 218 ? THR A 213 ILE A 218 1 ? 6  
HELX_P HELX_P7  AA7 THR A 230 ? ARG A 261 ? THR A 230 ARG A 261 1 ? 32 
HELX_P HELX_P8  AA8 ASP A 270 ? THR A 273 ? ASP A 270 THR A 273 5 ? 4  
HELX_P HELX_P9  AA9 ALA A 274 ? ILE A 290 ? ALA A 274 ILE A 290 1 ? 17 
HELX_P HELX_P10 AB1 ALA A 293 ? GLN A 312 ? ALA A 293 GLN A 312 1 ? 20 
HELX_P HELX_P11 AB2 LYS A 318 ? VAL A 322 ? LYS A 318 VAL A 322 5 ? 5  
HELX_P HELX_P12 AB3 GLU A 323 ? THR A 328 ? GLU A 323 THR A 328 5 ? 6  
HELX_P HELX_P13 AB4 SER A 367 ? CYS A 380 ? SER A 367 CYS A 380 1 ? 14 
HELX_P HELX_P14 AB5 ASP A 394 ? ASN A 407 ? ASP A 394 ASN A 407 1 ? 14 
HELX_P HELX_P15 AB6 ASN A 412 ? LYS A 417 ? ASN A 412 LYS A 417 1 ? 6  
HELX_P HELX_P16 AB7 GLY A 450 ? CYS A 458 ? GLY A 450 CYS A 458 1 ? 9  
HELX_P HELX_P17 AB8 THR A 471 ? GLN A 488 ? THR A 471 GLN A 488 1 ? 18 
HELX_P HELX_P18 AB9 ALA A 530 ? ALA A 541 ? ALA A 530 ALA A 541 1 ? 12 
HELX_P HELX_P19 AC1 HIS A 552 ? GLY A 564 ? HIS A 552 GLY A 564 1 ? 13 
HELX_P HELX_P20 AC2 GLY A 575 ? ASP A 579 ? GLY A 575 ASP A 579 1 ? 5  
HELX_P HELX_P21 AC3 PRO A 582 ? GLU A 591 ? PRO A 582 GLU A 591 1 ? 10 
HELX_P HELX_P22 AC4 SER A 600 ? LYS A 614 ? SER A 600 LYS A 614 1 ? 15 
HELX_P HELX_P23 AC5 ASP A 627 ? ALA A 634 ? ASP A 627 ALA A 634 1 ? 8  
HELX_P HELX_P24 AC6 THR A 644 ? ALA A 651 ? THR A 644 ALA A 651 1 ? 8  
HELX_P HELX_P25 AC7 ASN A 659 ? LEU A 701 ? ASN A 659 LEU A 701 1 ? 43 
HELX_P HELX_P26 AC8 THR A 708 ? ASN A 719 ? THR A 708 ASN A 719 1 ? 12 
HELX_P HELX_P27 AC9 SER A 721 ? MET A 729 ? SER A 721 MET A 729 1 ? 9  
HELX_P HELX_P28 AD1 ASP A 735 ? ARG A 739 ? ASP A 735 ARG A 739 5 ? 5  
HELX_P HELX_P29 AD2 ALA A 750 ? GLN A 777 ? ALA A 750 GLN A 777 1 ? 28 
HELX_P HELX_P30 AD3 SER A 779 ? ALA A 802 ? SER A 779 ALA A 802 1 ? 24 
HELX_P HELX_P31 AD4 THR A 808 ? GLY A 813 ? THR A 808 GLY A 813 1 ? 6  
HELX_P HELX_P32 AD5 ASN A 817 ? GLY A 832 ? ASN A 817 GLY A 832 1 ? 16 
HELX_P HELX_P33 AD6 LEU A 836 ? ARG A 840 ? LEU A 836 ARG A 840 5 ? 5  
HELX_P HELX_P34 AD7 LEU A 851 ? PHE A 878 ? LEU A 851 PHE A 878 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A VAL 287 O   ? ? ? 1_555 B CA . CA ? ? A VAL 287 A CA 901 1_555 ? ? ? ? ? ? ? 2.526 ? ? 
metalc2 metalc ? ? A ALA 288 O   ? ? ? 1_555 B CA . CA ? ? A ALA 288 A CA 901 1_555 ? ? ? ? ? ? ? 2.805 ? ? 
metalc3 metalc ? ? A ILE 290 O   ? ? ? 1_555 B CA . CA ? ? A ILE 290 A CA 901 1_555 ? ? ? ? ? ? ? 2.095 ? ? 
metalc4 metalc ? ? A GLU 292 OE1 ? ? ? 1_555 B CA . CA ? ? A GLU 292 A CA 901 1_555 ? ? ? ? ? ? ? 2.642 ? ? 
metalc5 metalc ? ? A ASN 716 OD1 ? ? ? 1_555 B CA . CA ? ? A ASN 716 A CA 901 1_555 ? ? ? ? ? ? ? 2.253 ? ? 
metalc6 metalc ? ? A ASP 720 OD2 ? ? ? 1_555 B CA . CA ? ? A ASP 720 A CA 901 1_555 ? ? ? ? ? ? ? 2.551 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A VAL 287 ? A VAL 287 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 O   ? A ALA 288 ? A ALA 288 ? 1_555 76.7  ? 
2  O   ? A VAL 287 ? A VAL 287 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 O   ? A ILE 290 ? A ILE 290 ? 1_555 92.8  ? 
3  O   ? A ALA 288 ? A ALA 288 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 O   ? A ILE 290 ? A ILE 290 ? 1_555 94.8  ? 
4  O   ? A VAL 287 ? A VAL 287 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OE1 ? A GLU 292 ? A GLU 292 ? 1_555 84.4  ? 
5  O   ? A ALA 288 ? A ALA 288 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OE1 ? A GLU 292 ? A GLU 292 ? 1_555 158.9 ? 
6  O   ? A ILE 290 ? A ILE 290 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OE1 ? A GLU 292 ? A GLU 292 ? 1_555 76.5  ? 
7  O   ? A VAL 287 ? A VAL 287 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD1 ? A ASN 716 ? A ASN 716 ? 1_555 74.4  ? 
8  O   ? A ALA 288 ? A ALA 288 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD1 ? A ASN 716 ? A ASN 716 ? 1_555 91.2  ? 
9  O   ? A ILE 290 ? A ILE 290 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD1 ? A ASN 716 ? A ASN 716 ? 1_555 164.3 ? 
10 OE1 ? A GLU 292 ? A GLU 292 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD1 ? A ASN 716 ? A ASN 716 ? 1_555 92.9  ? 
11 O   ? A VAL 287 ? A VAL 287 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD2 ? A ASP 720 ? A ASP 720 ? 1_555 170.9 ? 
12 O   ? A ALA 288 ? A ALA 288 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD2 ? A ASP 720 ? A ASP 720 ? 1_555 97.1  ? 
13 O   ? A ILE 290 ? A ILE 290 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD2 ? A ASP 720 ? A ASP 720 ? 1_555 94.4  ? 
14 OE1 ? A GLU 292 ? A GLU 292 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD2 ? A ASP 720 ? A ASP 720 ? 1_555 102.7 ? 
15 OD1 ? A ASN 716 ? A ASN 716 ? 1_555 CA ? B CA . ? A CA 901 ? 1_555 OD2 ? A ASP 720 ? A ASP 720 ? 1_555 99.2  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 3 ? 
AA3 ? 3 ? 
AA4 ? 4 ? 
AA5 ? 5 ? 
AA6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 124 ? ILE A 126 ? GLN A 124 ILE A 126 
AA1 2 ALA A 115 ? ARG A 119 ? ALA A 115 ARG A 119 
AA1 3 VAL A 136 ? LEU A 139 ? VAL A 136 LEU A 139 
AA1 4 GLY A 202 ? VAL A 206 ? GLY A 202 VAL A 206 
AA1 5 GLY A 149 ? GLU A 153 ? GLY A 149 GLU A 153 
AA1 6 MET A 190 ? VAL A 191 ? MET A 190 VAL A 191 
AA2 1 GLU A 167 ? GLU A 172 ? GLU A 167 GLU A 172 
AA2 2 LYS A 158 ? GLU A 161 ? LYS A 158 GLU A 161 
AA2 3 LEU A 196 ? TYR A 199 ? LEU A 196 TYR A 199 
AA3 1 ALA A 314 ? ILE A 316 ? ALA A 314 ILE A 316 
AA3 2 MET A 653 ? LEU A 655 ? MET A 653 LEU A 655 
AA3 3 VAL A 638 ? MET A 640 ? VAL A 638 MET A 640 
AA4 1 VAL A 330 ? ASP A 334 ? VAL A 330 ASP A 334 
AA4 2 ARG A 544 ? THR A 549 ? ARG A 544 THR A 549 
AA4 3 ILE A 593 ? ALA A 597 ? ILE A 593 ALA A 597 
AA4 4 ILE A 571 ? THR A 574 ? ILE A 571 THR A 574 
AA5 1 THR A 345 ? TYR A 350 ? THR A 345 TYR A 350 
AA5 2 VAL A 516 ? ILE A 524 ? VAL A 516 ILE A 524 
AA5 3 LEU A 490 ? GLY A 496 ? LEU A 490 GLY A 496 
AA5 4 LEU A 446 ? GLY A 449 ? LEU A 446 GLY A 449 
AA5 5 SER A 434 ? THR A 435 ? SER A 434 THR A 435 
AA6 1 THR A 345 ? TYR A 350 ? THR A 345 TYR A 350 
AA6 2 VAL A 516 ? ILE A 524 ? VAL A 516 ILE A 524 
AA6 3 TYR A 460 ? LEU A 463 ? TYR A 460 LEU A 463 
AA6 4 GLU A 466 ? LYS A 468 ? GLU A 466 LYS A 468 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLN A 124 ? O GLN A 124 N VAL A 117 ? N VAL A 117 
AA1 2 3 N ILE A 118 ? N ILE A 118 O VAL A 136 ? O VAL A 136 
AA1 3 4 N VAL A 137 ? N VAL A 137 O PHE A 204 ? O PHE A 204 
AA1 4 5 O VAL A 205 ? O VAL A 205 N ARG A 150 ? N ARG A 150 
AA1 5 6 N GLY A 149 ? N GLY A 149 O VAL A 191 ? O VAL A 191 
AA2 1 2 O GLU A 167 ? O GLU A 167 N GLU A 161 ? N GLU A 161 
AA2 2 3 N LYS A 158 ? N LYS A 158 O VAL A 198 ? O VAL A 198 
AA3 1 2 N ILE A 315 ? N ILE A 315 O ILE A 654 ? O ILE A 654 
AA3 2 3 O MET A 653 ? O MET A 653 N ALA A 639 ? N ALA A 639 
AA4 1 2 N THR A 333 ? N THR A 333 O VAL A 546 ? O VAL A 546 
AA4 2 3 N MET A 547 ? N MET A 547 O ALA A 594 ? O ALA A 594 
AA4 3 4 O ALA A 594 ? O ALA A 594 N ILE A 571 ? N ILE A 571 
AA5 1 2 N TYR A 350 ? N TYR A 350 O LEU A 520 ? O LEU A 520 
AA5 2 3 O MET A 523 ? O MET A 523 N ARG A 491 ? N ARG A 491 
AA5 3 4 O ALA A 494 ? O ALA A 494 N GLY A 449 ? N GLY A 449 
AA5 4 5 O LEU A 446 ? O LEU A 446 N THR A 435 ? N THR A 435 
AA6 1 2 N TYR A 350 ? N TYR A 350 O LEU A 520 ? O LEU A 520 
AA6 2 3 O LEU A 517 ? O LEU A 517 N TYR A 460 ? N TYR A 460 
AA6 3 4 N VAL A 461 ? N VAL A 461 O LYS A 468 ? O LYS A 468 
# 
_pdbx_entry_details.entry_id                   9EVC 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 37  ? ? -109.79 42.44   
2  1 THR A 54  ? ? -89.39  30.18   
3  1 SER A 111 ? ? -96.61  32.15   
4  1 ARG A 119 ? ? 52.59   -139.11 
5  1 LEU A 263 ? ? 54.43   17.41   
6  1 LEU A 264 ? ? 54.47   -134.81 
7  1 ALA A 269 ? ? 54.26   -97.08  
8  1 PRO A 320 ? ? -67.66  2.04    
9  1 ASN A 342 ? ? 56.61   -161.78 
10 1 ASN A 358 ? ? -140.26 18.62   
11 1 TRP A 366 ? ? 61.45   -136.12 
12 1 ASN A 386 ? ? 49.91   -136.15 
13 1 GLN A 409 ? ? 62.20   -136.73 
14 1 LYS A 417 ? ? -92.79  48.66   
15 1 PHE A 418 ? ? -161.86 112.54  
16 1 ASP A 464 ? ? 58.48   -123.67 
17 1 ALA A 502 ? ? 43.30   -132.71 
18 1 ASP A 503 ? ? -162.02 -162.70 
19 1 GLU A 510 ? ? 55.37   -113.37 
20 1 ALA A 568 ? ? 59.38   -107.61 
21 1 LYS A 614 ? ? -93.16  50.72   
22 1 ASP A 658 ? ? 72.77   -6.67   
23 1 SER A 721 ? ? -159.63 -157.83 
24 1 PRO A 734 ? ? -66.59  4.63    
25 1 ILE A 778 ? ? -104.14 -63.85  
26 1 ALA A 847 ? ? 58.87   -150.92 
27 1 LEU A 851 ? ? -134.18 -35.95  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9EVC 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9EVC 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.73 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               78203 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Calcium-transporting ATPase' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9EVC 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            OTHER 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9EVC 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9EVC 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLU 19  ? A GLU 19  
2  1 Y 1 A LYS 20  ? A LYS 20  
3  1 Y 1 A GLY 21  ? A GLY 21  
4  1 Y 1 A LEU 22  ? A LEU 22  
5  1 Y 1 A THR 23  ? A THR 23  
6  1 Y 1 A THR 24  ? A THR 24  
7  1 Y 1 A SER 25  ? A SER 25  
8  1 Y 1 A LEU 39  ? A LEU 39  
9  1 Y 1 A LYS 40  ? A LYS 40  
10 1 Y 1 A ASN 41  ? A ASN 41  
11 1 Y 1 A LYS 42  ? A LYS 42  
12 1 Y 1 A LYS 43  ? A LYS 43  
13 1 Y 1 A LYS 44  ? A LYS 44  
14 1 Y 1 A ALA 219 ? A ALA 219 
15 1 Y 1 A GLY 220 ? A GLY 220 
16 1 Y 1 A LEU 221 ? A LEU 221 
17 1 Y 1 A LEU 222 ? A LEU 222 
18 1 Y 1 A GLU 223 ? A GLU 223 
19 1 Y 1 A THR 224 ? A THR 224 
20 1 Y 1 A ALA 225 ? A ALA 225 
21 1 Y 1 A GLU 226 ? A GLU 226 
22 1 Y 1 A ALA 227 ? A ALA 227 
23 1 Y 1 A LYS 228 ? A LYS 228 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-28 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9EVC 
_em_admin.last_update        2025-02-19 
_em_admin.map_release_date   2025-02-05 
_em_admin.title              'CryoEM structure of LMCA1 in E1-Ca state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          1639 
_em_entity_assembly_naturalsource.organism             'Listeria monocytogenes' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Swedish Research Council' 
_pdbx_audit_support.country                Sweden 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9EVC 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA A 1 1   ? 156.897 159.456 176.703 1.00 125.47 ? 1   ALA A N   1 
ATOM   2    C  CA  . ALA A 1 1   ? 156.146 160.703 176.627 1.00 125.47 ? 1   ALA A CA  1 
ATOM   3    C  C   . ALA A 1 1   ? 155.856 161.251 178.021 1.00 125.47 ? 1   ALA A C   1 
ATOM   4    O  O   . ALA A 1 1   ? 154.699 161.489 178.373 1.00 125.47 ? 1   ALA A O   1 
ATOM   5    C  CB  . ALA A 1 1   ? 154.852 160.496 175.858 1.00 125.47 ? 1   ALA A CB  1 
ATOM   6    N  N   . GLU A 1 2   ? 156.920 161.428 178.806 1.00 127.42 ? 2   GLU A N   1 
ATOM   7    C  CA  . GLU A 1 2   ? 156.893 161.973 180.162 1.00 127.42 ? 2   GLU A CA  1 
ATOM   8    C  C   . GLU A 1 2   ? 156.055 161.143 181.129 1.00 127.42 ? 2   GLU A C   1 
ATOM   9    O  O   . GLU A 1 2   ? 155.643 161.652 182.178 1.00 127.42 ? 2   GLU A O   1 
ATOM   10   C  CB  . GLU A 1 2   ? 156.411 163.431 180.177 1.00 127.42 ? 2   GLU A CB  1 
ATOM   11   C  CG  . GLU A 1 2   ? 157.529 164.457 180.127 1.00 127.42 ? 2   GLU A CG  1 
ATOM   12   C  CD  . GLU A 1 2   ? 157.818 165.062 181.486 1.00 127.42 ? 2   GLU A CD  1 
ATOM   13   O  OE1 . GLU A 1 2   ? 157.692 164.339 182.496 1.00 127.42 ? 2   GLU A OE1 1 
ATOM   14   O  OE2 . GLU A 1 2   ? 158.165 166.260 181.545 1.00 127.42 ? 2   GLU A OE2 1 
ATOM   15   N  N   . ILE A 1 3   ? 155.790 159.874 180.806 1.00 133.99 ? 3   ILE A N   1 
ATOM   16   C  CA  . ILE A 1 3   ? 155.048 158.988 181.694 1.00 133.99 ? 3   ILE A CA  1 
ATOM   17   C  C   . ILE A 1 3   ? 155.920 157.886 182.266 1.00 133.99 ? 3   ILE A C   1 
ATOM   18   O  O   . ILE A 1 3   ? 155.424 157.040 183.023 1.00 133.99 ? 3   ILE A O   1 
ATOM   19   C  CB  . ILE A 1 3   ? 153.834 158.373 180.970 1.00 133.99 ? 3   ILE A CB  1 
ATOM   20   C  CG1 . ILE A 1 3   ? 154.275 157.728 179.656 1.00 133.99 ? 3   ILE A CG1 1 
ATOM   21   C  CG2 . ILE A 1 3   ? 152.777 159.434 180.711 1.00 133.99 ? 3   ILE A CG2 1 
ATOM   22   C  CD1 . ILE A 1 3   ? 153.157 157.032 178.915 1.00 133.99 ? 3   ILE A CD1 1 
ATOM   23   N  N   . TYR A 1 4   ? 157.209 157.865 181.923 1.00 147.05 ? 4   TYR A N   1 
ATOM   24   C  CA  . TYR A 1 4   ? 158.085 156.800 182.397 1.00 147.05 ? 4   TYR A CA  1 
ATOM   25   C  C   . TYR A 1 4   ? 158.476 157.017 183.852 1.00 147.05 ? 4   TYR A C   1 
ATOM   26   O  O   . TYR A 1 4   ? 158.647 156.055 184.608 1.00 147.05 ? 4   TYR A O   1 
ATOM   27   C  CB  . TYR A 1 4   ? 159.331 156.727 181.520 1.00 147.05 ? 4   TYR A CB  1 
ATOM   28   C  CG  . TYR A 1 4   ? 159.382 155.502 180.647 1.00 147.05 ? 4   TYR A CG  1 
ATOM   29   C  CD1 . TYR A 1 4   ? 159.757 154.268 181.160 1.00 147.05 ? 4   TYR A CD1 1 
ATOM   30   C  CD2 . TYR A 1 4   ? 159.052 155.581 179.302 1.00 147.05 ? 4   TYR A CD2 1 
ATOM   31   C  CE1 . TYR A 1 4   ? 159.800 153.146 180.353 1.00 147.05 ? 4   TYR A CE1 1 
ATOM   32   C  CE2 . TYR A 1 4   ? 159.091 154.469 178.490 1.00 147.05 ? 4   TYR A CE2 1 
ATOM   33   C  CZ  . TYR A 1 4   ? 159.466 153.255 179.019 1.00 147.05 ? 4   TYR A CZ  1 
ATOM   34   O  OH  . TYR A 1 4   ? 159.503 152.148 178.205 1.00 147.05 ? 4   TYR A OH  1 
ATOM   35   N  N   . ARG A 1 5   ? 158.628 158.277 184.255 1.00 147.16 ? 5   ARG A N   1 
ATOM   36   C  CA  . ARG A 1 5   ? 159.140 158.631 185.571 1.00 147.16 ? 5   ARG A CA  1 
ATOM   37   C  C   . ARG A 1 5   ? 158.075 158.614 186.657 1.00 147.16 ? 5   ARG A C   1 
ATOM   38   O  O   . ARG A 1 5   ? 158.423 158.692 187.841 1.00 147.16 ? 5   ARG A O   1 
ATOM   39   C  CB  . ARG A 1 5   ? 159.782 160.016 185.504 1.00 147.16 ? 5   ARG A CB  1 
ATOM   40   C  CG  . ARG A 1 5   ? 160.697 160.192 184.307 1.00 147.16 ? 5   ARG A CG  1 
ATOM   41   C  CD  . ARG A 1 5   ? 161.265 161.599 184.233 1.00 147.16 ? 5   ARG A CD  1 
ATOM   42   N  NE  . ARG A 1 5   ? 162.380 161.689 183.298 1.00 147.16 ? 5   ARG A NE  1 
ATOM   43   C  CZ  . ARG A 1 5   ? 162.262 161.689 181.976 1.00 147.16 ? 5   ARG A CZ  1 
ATOM   44   N  NH1 . ARG A 1 5   ? 161.079 161.634 181.385 1.00 147.16 ? 5   ARG A NH1 1 
ATOM   45   N  NH2 . ARG A 1 5   ? 163.360 161.754 181.228 1.00 147.16 ? 5   ARG A NH2 1 
ATOM   46   N  N   . LYS A 1 6   ? 156.800 158.521 186.294 1.00 151.97 ? 6   LYS A N   1 
ATOM   47   C  CA  . LYS A 1 6   ? 155.716 158.659 187.255 1.00 151.97 ? 6   LYS A CA  1 
ATOM   48   C  C   . LYS A 1 6   ? 155.284 157.304 187.802 1.00 151.97 ? 6   LYS A C   1 
ATOM   49   O  O   . LYS A 1 6   ? 155.266 156.301 187.081 1.00 151.97 ? 6   LYS A O   1 
ATOM   50   C  CB  . LYS A 1 6   ? 154.521 159.369 186.618 1.00 151.97 ? 6   LYS A CB  1 
ATOM   51   C  CG  . LYS A 1 6   ? 154.864 160.702 185.972 1.00 151.97 ? 6   LYS A CG  1 
ATOM   52   C  CD  . LYS A 1 6   ? 155.359 161.703 187.004 1.00 151.97 ? 6   LYS A CD  1 
ATOM   53   C  CE  . LYS A 1 6   ? 154.244 162.631 187.457 1.00 151.97 ? 6   LYS A CE  1 
ATOM   54   N  NZ  . LYS A 1 6   ? 154.591 164.066 187.263 1.00 151.97 ? 6   LYS A NZ  1 
ATOM   55   N  N   . SER A 1 7   ? 154.936 157.286 189.086 1.00 148.48 ? 7   SER A N   1 
ATOM   56   C  CA  . SER A 1 7   ? 154.418 156.094 189.743 1.00 148.48 ? 7   SER A CA  1 
ATOM   57   C  C   . SER A 1 7   ? 152.911 156.003 189.507 1.00 148.48 ? 7   SER A C   1 
ATOM   58   O  O   . SER A 1 7   ? 152.352 156.685 188.644 1.00 148.48 ? 7   SER A O   1 
ATOM   59   C  CB  . SER A 1 7   ? 154.766 156.112 191.229 1.00 148.48 ? 7   SER A CB  1 
ATOM   60   O  OG  . SER A 1 7   ? 156.168 156.051 191.423 1.00 148.48 ? 7   SER A OG  1 
ATOM   61   N  N   . ALA A 1 8   ? 152.237 155.139 190.270 1.00 144.61 ? 8   ALA A N   1 
ATOM   62   C  CA  . ALA A 1 8   ? 150.796 154.958 190.110 1.00 144.61 ? 8   ALA A CA  1 
ATOM   63   C  C   . ALA A 1 8   ? 150.036 156.227 190.478 1.00 144.61 ? 8   ALA A C   1 
ATOM   64   O  O   . ALA A 1 8   ? 149.321 156.803 189.648 1.00 144.61 ? 8   ALA A O   1 
ATOM   65   C  CB  . ALA A 1 8   ? 150.323 153.776 190.959 1.00 144.61 ? 8   ALA A CB  1 
ATOM   66   N  N   . ALA A 1 9   ? 150.190 156.686 191.725 1.00 141.91 ? 9   ALA A N   1 
ATOM   67   C  CA  . ALA A 1 9   ? 149.500 157.893 192.168 1.00 141.91 ? 9   ALA A CA  1 
ATOM   68   C  C   . ALA A 1 9   ? 149.979 159.125 191.413 1.00 141.91 ? 9   ALA A C   1 
ATOM   69   O  O   . ALA A 1 9   ? 149.195 160.049 191.168 1.00 141.91 ? 9   ALA A O   1 
ATOM   70   C  CB  . ALA A 1 9   ? 149.689 158.085 193.673 1.00 141.91 ? 9   ALA A CB  1 
ATOM   71   N  N   . GLU A 1 10  ? 151.257 159.156 191.030 1.00 147.75 ? 10  GLU A N   1 
ATOM   72   C  CA  . GLU A 1 10  ? 151.757 160.269 190.233 1.00 147.75 ? 10  GLU A CA  1 
ATOM   73   C  C   . GLU A 1 10  ? 151.148 160.279 188.835 1.00 147.75 ? 10  GLU A C   1 
ATOM   74   O  O   . GLU A 1 10  ? 150.901 161.355 188.281 1.00 147.75 ? 10  GLU A O   1 
ATOM   75   C  CB  . GLU A 1 10  ? 153.284 160.224 190.176 1.00 147.75 ? 10  GLU A CB  1 
ATOM   76   C  CG  . GLU A 1 10  ? 153.926 160.072 191.551 1.00 147.75 ? 10  GLU A CG  1 
ATOM   77   C  CD  . GLU A 1 10  ? 155.389 159.678 191.491 1.00 147.75 ? 10  GLU A CD  1 
ATOM   78   O  OE1 . GLU A 1 10  ? 155.820 159.124 190.460 1.00 147.75 ? 10  GLU A OE1 1 
ATOM   79   O  OE2 . GLU A 1 10  ? 156.111 159.922 192.481 1.00 147.75 ? 10  GLU A OE2 1 
ATOM   80   N  N   . THR A 1 11  ? 150.888 159.103 188.253 1.00 147.40 ? 11  THR A N   1 
ATOM   81   C  CA  . THR A 1 11  ? 150.162 159.061 186.986 1.00 147.40 ? 11  THR A CA  1 
ATOM   82   C  C   . THR A 1 11  ? 148.705 159.462 187.173 1.00 147.40 ? 11  THR A C   1 
ATOM   83   O  O   . THR A 1 11  ? 148.104 160.068 186.277 1.00 147.40 ? 11  THR A O   1 
ATOM   84   C  CB  . THR A 1 11  ? 150.247 157.669 186.357 1.00 147.40 ? 11  THR A CB  1 
ATOM   85   O  OG1 . THR A 1 11  ? 150.214 156.672 187.384 1.00 147.40 ? 11  THR A OG1 1 
ATOM   86   C  CG2 . THR A 1 11  ? 151.525 157.522 185.546 1.00 147.40 ? 11  THR A CG2 1 
ATOM   87   N  N   . PHE A 1 12  ? 148.113 159.112 188.320 1.00 137.25 ? 12  PHE A N   1 
ATOM   88   C  CA  . PHE A 1 12  ? 146.746 159.540 188.604 1.00 137.25 ? 12  PHE A CA  1 
ATOM   89   C  C   . PHE A 1 12  ? 146.653 161.059 188.706 1.00 137.25 ? 12  PHE A C   1 
ATOM   90   O  O   . PHE A 1 12  ? 145.691 161.665 188.222 1.00 137.25 ? 12  PHE A O   1 
ATOM   91   C  CB  . PHE A 1 12  ? 146.237 158.896 189.896 1.00 137.25 ? 12  PHE A CB  1 
ATOM   92   C  CG  . PHE A 1 12  ? 145.968 157.420 189.783 1.00 137.25 ? 12  PHE A CG  1 
ATOM   93   C  CD1 . PHE A 1 12  ? 145.206 156.918 188.742 1.00 137.25 ? 12  PHE A CD1 1 
ATOM   94   C  CD2 . PHE A 1 12  ? 146.443 156.540 190.742 1.00 137.25 ? 12  PHE A CD2 1 
ATOM   95   C  CE1 . PHE A 1 12  ? 144.949 155.564 188.642 1.00 137.25 ? 12  PHE A CE1 1 
ATOM   96   C  CE2 . PHE A 1 12  ? 146.190 155.184 190.648 1.00 137.25 ? 12  PHE A CE2 1 
ATOM   97   C  CZ  . PHE A 1 12  ? 145.440 154.696 189.597 1.00 137.25 ? 12  PHE A CZ  1 
ATOM   98   N  N   . THR A 1 13  ? 147.643 161.688 189.340 1.00 133.10 ? 13  THR A N   1 
ATOM   99   C  CA  . THR A 1 13  ? 147.597 163.132 189.551 1.00 133.10 ? 13  THR A CA  1 
ATOM   100  C  C   . THR A 1 13  ? 147.985 163.907 188.294 1.00 133.10 ? 13  THR A C   1 
ATOM   101  O  O   . THR A 1 13  ? 147.293 164.855 187.907 1.00 133.10 ? 13  THR A O   1 
ATOM   102  C  CB  . THR A 1 13  ? 148.506 163.524 190.717 1.00 133.10 ? 13  THR A CB  1 
ATOM   103  O  OG1 . THR A 1 13  ? 149.819 162.991 190.505 1.00 133.10 ? 13  THR A OG1 1 
ATOM   104  C  CG2 . THR A 1 13  ? 147.949 162.994 192.031 1.00 133.10 ? 13  THR A CG2 1 
ATOM   105  N  N   . GLN A 1 14  ? 149.093 163.525 187.652 1.00 132.14 ? 14  GLN A N   1 
ATOM   106  C  CA  . GLN A 1 14  ? 149.622 164.307 186.537 1.00 132.14 ? 14  GLN A CA  1 
ATOM   107  C  C   . GLN A 1 14  ? 148.715 164.234 185.314 1.00 132.14 ? 14  GLN A C   1 
ATOM   108  O  O   . GLN A 1 14  ? 148.375 165.262 184.719 1.00 132.14 ? 14  GLN A O   1 
ATOM   109  C  CB  . GLN A 1 14  ? 151.028 163.823 186.183 1.00 132.14 ? 14  GLN A CB  1 
ATOM   110  C  CG  . GLN A 1 14  ? 151.821 164.788 185.318 1.00 132.14 ? 14  GLN A CG  1 
ATOM   111  C  CD  . GLN A 1 14  ? 152.468 164.104 184.129 1.00 132.14 ? 14  GLN A CD  1 
ATOM   112  O  OE1 . GLN A 1 14  ? 153.191 163.119 184.282 1.00 132.14 ? 14  GLN A OE1 1 
ATOM   113  N  NE2 . GLN A 1 14  ? 152.210 164.623 182.934 1.00 132.14 ? 14  GLN A NE2 1 
ATOM   114  N  N   . LEU A 1 15  ? 148.315 163.007 184.936 1.00 133.39 ? 15  LEU A N   1 
ATOM   115  C  CA  . LEU A 1 15  ? 147.503 162.780 183.703 1.00 133.39 ? 15  LEU A CA  1 
ATOM   116  C  C   . LEU A 1 15  ? 146.006 162.780 184.025 1.00 133.39 ? 15  LEU A C   1 
ATOM   117  O  O   . LEU A 1 15  ? 145.212 162.442 183.127 1.00 133.39 ? 15  LEU A O   1 
ATOM   118  C  CB  . LEU A 1 15  ? 147.913 161.421 183.124 1.00 133.39 ? 15  LEU A CB  1 
ATOM   119  C  CG  . LEU A 1 15  ? 147.149 160.952 181.887 1.00 133.39 ? 15  LEU A CG  1 
ATOM   120  C  CD1 . LEU A 1 15  ? 147.378 161.900 180.721 1.00 133.39 ? 15  LEU A CD1 1 
ATOM   121  C  CD2 . LEU A 1 15  ? 147.558 159.537 181.503 1.00 133.39 ? 15  LEU A CD2 1 
ATOM   122  N  N   . GLU A 1 16  ? 145.637 163.134 185.252 1.00 131.42 ? 16  GLU A N   1 
ATOM   123  C  CA  . GLU A 1 16  ? 144.237 163.173 185.691 1.00 131.42 ? 16  GLU A CA  1 
ATOM   124  C  C   . GLU A 1 16  ? 143.545 161.828 185.473 1.00 131.42 ? 16  GLU A C   1 
ATOM   125  O  O   . GLU A 1 16  ? 142.390 161.765 185.051 1.00 131.42 ? 16  GLU A O   1 
ATOM   126  C  CB  . GLU A 1 16  ? 143.457 164.305 185.012 1.00 131.42 ? 16  GLU A CB  1 
ATOM   127  C  CG  . GLU A 1 16  ? 144.183 165.640 184.975 1.00 131.42 ? 16  GLU A CG  1 
ATOM   128  C  CD  . GLU A 1 16  ? 144.671 166.000 183.584 1.00 131.42 ? 16  GLU A CD  1 
ATOM   129  O  OE1 . GLU A 1 16  ? 144.310 165.291 182.621 1.00 131.42 ? 16  GLU A OE1 1 
ATOM   130  O  OE2 . GLU A 1 16  ? 145.419 166.992 183.453 1.00 131.42 ? 16  GLU A OE2 1 
ATOM   131  N  N   . ALA A 1 17  ? 144.261 160.745 185.764 1.00 134.24 ? 17  ALA A N   1 
ATOM   132  C  CA  . ALA A 1 17  ? 143.693 159.408 185.685 1.00 134.24 ? 17  ALA A CA  1 
ATOM   133  C  C   . ALA A 1 17  ? 142.881 159.112 186.938 1.00 134.24 ? 17  ALA A C   1 
ATOM   134  O  O   . ALA A 1 17  ? 143.334 159.366 188.058 1.00 134.24 ? 17  ALA A O   1 
ATOM   135  C  CB  . ALA A 1 17  ? 144.797 158.367 185.513 1.00 134.24 ? 17  ALA A CB  1 
ATOM   136  N  N   . THR A 1 18  ? 141.682 158.575 186.750 1.00 138.91 ? 18  THR A N   1 
ATOM   137  C  CA  . THR A 1 18  ? 140.838 158.225 187.886 1.00 138.91 ? 18  THR A CA  1 
ATOM   138  C  C   . THR A 1 18  ? 140.897 156.728 188.183 1.00 138.91 ? 18  THR A C   1 
ATOM   139  O  O   . THR A 1 18  ? 141.672 155.992 187.570 1.00 138.91 ? 18  THR A O   1 
ATOM   140  C  CB  . THR A 1 18  ? 139.385 158.641 187.646 1.00 138.91 ? 18  THR A CB  1 
ATOM   141  O  OG1 . THR A 1 18  ? 138.879 157.961 186.488 1.00 138.91 ? 18  THR A OG1 1 
ATOM   142  C  CG2 . THR A 1 18  ? 139.289 160.149 187.436 1.00 138.91 ? 18  THR A CG2 1 
ATOM   143  N  N   . GLU A 1 26  ? 132.348 164.209 180.766 1.00 138.52 ? 26  GLU A N   1 
ATOM   144  C  CA  . GLU A 1 26  ? 133.768 164.383 181.049 1.00 138.52 ? 26  GLU A CA  1 
ATOM   145  C  C   . GLU A 1 26  ? 134.610 163.422 180.218 1.00 138.52 ? 26  GLU A C   1 
ATOM   146  O  O   . GLU A 1 26  ? 135.655 163.800 179.682 1.00 138.52 ? 26  GLU A O   1 
ATOM   147  C  CB  . GLU A 1 26  ? 134.047 164.176 182.539 1.00 138.52 ? 26  GLU A CB  1 
ATOM   148  C  CG  . GLU A 1 26  ? 135.419 164.653 182.987 1.00 138.52 ? 26  GLU A CG  1 
ATOM   149  C  CD  . GLU A 1 26  ? 135.845 165.933 182.294 1.00 138.52 ? 26  GLU A CD  1 
ATOM   150  O  OE1 . GLU A 1 26  ? 135.242 166.991 182.574 1.00 138.52 ? 26  GLU A OE1 1 
ATOM   151  O  OE2 . GLU A 1 26  ? 136.783 165.882 181.471 1.00 138.52 ? 26  GLU A OE2 1 
ATOM   152  N  N   . VAL A 1 27  ? 134.143 162.175 180.117 1.00 132.16 ? 27  VAL A N   1 
ATOM   153  C  CA  . VAL A 1 27  ? 134.863 161.169 179.342 1.00 132.16 ? 27  VAL A CA  1 
ATOM   154  C  C   . VAL A 1 27  ? 134.876 161.540 177.862 1.00 132.16 ? 27  VAL A C   1 
ATOM   155  O  O   . VAL A 1 27  ? 135.895 161.384 177.181 1.00 132.16 ? 27  VAL A O   1 
ATOM   156  C  CB  . VAL A 1 27  ? 134.265 159.769 179.596 1.00 132.16 ? 27  VAL A CB  1 
ATOM   157  C  CG1 . VAL A 1 27  ? 132.760 159.745 179.341 1.00 132.16 ? 27  VAL A CG1 1 
ATOM   158  C  CG2 . VAL A 1 27  ? 134.975 158.717 178.755 1.00 132.16 ? 27  VAL A CG2 1 
ATOM   159  N  N   . THR A 1 28  ? 133.765 162.077 177.349 1.00 133.28 ? 28  THR A N   1 
ATOM   160  C  CA  . THR A 1 28  ? 133.741 162.541 175.966 1.00 133.28 ? 28  THR A CA  1 
ATOM   161  C  C   . THR A 1 28  ? 134.632 163.762 175.772 1.00 133.28 ? 28  THR A C   1 
ATOM   162  O  O   . THR A 1 28  ? 135.241 163.922 174.706 1.00 133.28 ? 28  THR A O   1 
ATOM   163  C  CB  . THR A 1 28  ? 132.307 162.857 175.539 1.00 133.28 ? 28  THR A CB  1 
ATOM   164  O  OG1 . THR A 1 28  ? 131.413 161.899 176.120 1.00 133.28 ? 28  THR A OG1 1 
ATOM   165  C  CG2 . THR A 1 28  ? 132.179 162.804 174.024 1.00 133.28 ? 28  THR A CG2 1 
ATOM   166  N  N   . LYS A 1 29  ? 134.716 164.630 176.785 1.00 133.67 ? 29  LYS A N   1 
ATOM   167  C  CA  . LYS A 1 29  ? 135.620 165.773 176.715 1.00 133.67 ? 29  LYS A CA  1 
ATOM   168  C  C   . LYS A 1 29  ? 137.073 165.321 176.636 1.00 133.67 ? 29  LYS A C   1 
ATOM   169  O  O   . LYS A 1 29  ? 137.864 165.877 175.866 1.00 133.67 ? 29  LYS A O   1 
ATOM   170  C  CB  . LYS A 1 29  ? 135.406 166.686 177.922 1.00 133.67 ? 29  LYS A CB  1 
ATOM   171  C  CG  . LYS A 1 29  ? 133.945 166.950 178.249 1.00 133.67 ? 29  LYS A CG  1 
ATOM   172  C  CD  . LYS A 1 29  ? 133.249 167.694 177.121 1.00 133.67 ? 29  LYS A CD  1 
ATOM   173  C  CE  . LYS A 1 29  ? 133.830 169.086 176.938 1.00 133.67 ? 29  LYS A CE  1 
ATOM   174  N  NZ  . LYS A 1 29  ? 133.568 169.954 178.119 1.00 133.67 ? 29  LYS A NZ  1 
ATOM   175  N  N   . ARG A 1 30  ? 137.442 164.307 177.424 1.00 139.34 ? 30  ARG A N   1 
ATOM   176  C  CA  . ARG A 1 30  ? 138.786 163.747 177.313 1.00 139.34 ? 30  ARG A CA  1 
ATOM   177  C  C   . ARG A 1 30  ? 138.994 163.043 175.978 1.00 139.34 ? 30  ARG A C   1 
ATOM   178  O  O   . ARG A 1 30  ? 140.108 163.053 175.443 1.00 139.34 ? 30  ARG A O   1 
ATOM   179  C  CB  . ARG A 1 30  ? 139.060 162.782 178.467 1.00 139.34 ? 30  ARG A CB  1 
ATOM   180  C  CG  . ARG A 1 30  ? 138.859 163.376 179.847 1.00 139.34 ? 30  ARG A CG  1 
ATOM   181  C  CD  . ARG A 1 30  ? 139.400 162.448 180.921 1.00 139.34 ? 30  ARG A CD  1 
ATOM   182  N  NE  . ARG A 1 30  ? 140.852 162.336 180.863 1.00 139.34 ? 30  ARG A NE  1 
ATOM   183  C  CZ  . ARG A 1 30  ? 141.640 162.281 181.928 1.00 139.34 ? 30  ARG A CZ  1 
ATOM   184  N  NH1 . ARG A 1 30  ? 141.148 162.327 183.154 1.00 139.34 ? 30  ARG A NH1 1 
ATOM   185  N  NH2 . ARG A 1 30  ? 142.955 162.177 181.757 1.00 139.34 ? 30  ARG A NH2 1 
ATOM   186  N  N   . GLN A 1 31  ? 137.944 162.417 175.437 1.00 141.84 ? 31  GLN A N   1 
ATOM   187  C  CA  . GLN A 1 31  ? 138.052 161.765 174.136 1.00 141.84 ? 31  GLN A CA  1 
ATOM   188  C  C   . GLN A 1 31  ? 138.344 162.773 173.032 1.00 141.84 ? 31  GLN A C   1 
ATOM   189  O  O   . GLN A 1 31  ? 139.195 162.531 172.168 1.00 141.84 ? 31  GLN A O   1 
ATOM   190  C  CB  . GLN A 1 31  ? 136.767 160.996 173.826 1.00 141.84 ? 31  GLN A CB  1 
ATOM   191  C  CG  . GLN A 1 31  ? 136.640 159.669 174.551 1.00 141.84 ? 31  GLN A CG  1 
ATOM   192  C  CD  . GLN A 1 31  ? 137.167 158.505 173.739 1.00 141.84 ? 31  GLN A CD  1 
ATOM   193  O  OE1 . GLN A 1 31  ? 137.931 158.687 172.791 1.00 141.84 ? 31  GLN A OE1 1 
ATOM   194  N  NE2 . GLN A 1 31  ? 136.759 157.298 174.108 1.00 141.84 ? 31  GLN A NE2 1 
ATOM   195  N  N   . GLU A 1 32  ? 137.646 163.910 173.041 1.00 134.75 ? 32  GLU A N   1 
ATOM   196  C  CA  . GLU A 1 32  ? 137.890 164.917 172.012 1.00 134.75 ? 32  GLU A CA  1 
ATOM   197  C  C   . GLU A 1 32  ? 139.131 165.750 172.308 1.00 134.75 ? 32  GLU A C   1 
ATOM   198  O  O   . GLU A 1 32  ? 139.657 166.407 171.403 1.00 134.75 ? 32  GLU A O   1 
ATOM   199  C  CB  . GLU A 1 32  ? 136.674 165.833 171.848 1.00 134.75 ? 32  GLU A CB  1 
ATOM   200  C  CG  . GLU A 1 32  ? 136.225 166.531 173.116 1.00 134.75 ? 32  GLU A CG  1 
ATOM   201  C  CD  . GLU A 1 32  ? 134.967 167.352 172.912 1.00 134.75 ? 32  GLU A CD  1 
ATOM   202  O  OE1 . GLU A 1 32  ? 134.027 166.848 172.262 1.00 134.75 ? 32  GLU A OE1 1 
ATOM   203  O  OE2 . GLU A 1 32  ? 134.919 168.500 173.399 1.00 134.75 ? 32  GLU A OE2 1 
ATOM   204  N  N   . LYS A 1 33  ? 139.614 165.739 173.552 1.00 129.09 ? 33  LYS A N   1 
ATOM   205  C  CA  . LYS A 1 33  ? 140.801 166.519 173.889 1.00 129.09 ? 33  LYS A CA  1 
ATOM   206  C  C   . LYS A 1 33  ? 142.076 165.703 173.704 1.00 129.09 ? 33  LYS A C   1 
ATOM   207  O  O   . LYS A 1 33  ? 142.991 166.124 172.989 1.00 129.09 ? 33  LYS A O   1 
ATOM   208  C  CB  . LYS A 1 33  ? 140.697 167.041 175.323 1.00 129.09 ? 33  LYS A CB  1 
ATOM   209  C  CG  . LYS A 1 33  ? 141.856 167.931 175.743 1.00 129.09 ? 33  LYS A CG  1 
ATOM   210  C  CD  . LYS A 1 33  ? 141.740 168.342 177.201 1.00 129.09 ? 33  LYS A CD  1 
ATOM   211  C  CE  . LYS A 1 33  ? 142.446 167.354 178.113 1.00 129.09 ? 33  LYS A CE  1 
ATOM   212  N  NZ  . LYS A 1 33  ? 143.714 166.855 177.514 1.00 129.09 ? 33  LYS A NZ  1 
ATOM   213  N  N   . TYR A 1 34  ? 142.156 164.533 174.346 1.00 132.28 ? 34  TYR A N   1 
ATOM   214  C  CA  . TYR A 1 34  ? 143.312 163.662 174.163 1.00 132.28 ? 34  TYR A CA  1 
ATOM   215  C  C   . TYR A 1 34  ? 143.372 163.068 172.763 1.00 132.28 ? 34  TYR A C   1 
ATOM   216  O  O   . TYR A 1 34  ? 144.450 162.653 172.325 1.00 132.28 ? 34  TYR A O   1 
ATOM   217  C  CB  . TYR A 1 34  ? 143.298 162.529 175.193 1.00 132.28 ? 34  TYR A CB  1 
ATOM   218  C  CG  . TYR A 1 34  ? 143.634 162.956 176.604 1.00 132.28 ? 34  TYR A CG  1 
ATOM   219  C  CD1 . TYR A 1 34  ? 142.656 163.470 177.447 1.00 132.28 ? 34  TYR A CD1 1 
ATOM   220  C  CD2 . TYR A 1 34  ? 144.927 162.838 177.097 1.00 132.28 ? 34  TYR A CD2 1 
ATOM   221  C  CE1 . TYR A 1 34  ? 142.958 163.857 178.739 1.00 132.28 ? 34  TYR A CE1 1 
ATOM   222  C  CE2 . TYR A 1 34  ? 145.239 163.223 178.388 1.00 132.28 ? 34  TYR A CE2 1 
ATOM   223  C  CZ  . TYR A 1 34  ? 144.250 163.733 179.204 1.00 132.28 ? 34  TYR A CZ  1 
ATOM   224  O  OH  . TYR A 1 34  ? 144.555 164.118 180.489 1.00 132.28 ? 34  TYR A OH  1 
ATOM   225  N  N   . GLY A 1 35  ? 142.253 163.018 172.060 1.00 135.08 ? 35  GLY A N   1 
ATOM   226  C  CA  . GLY A 1 35  ? 142.186 162.410 170.749 1.00 135.08 ? 35  GLY A CA  1 
ATOM   227  C  C   . GLY A 1 35  ? 141.713 160.971 170.818 1.00 135.08 ? 35  GLY A C   1 
ATOM   228  O  O   . GLY A 1 35  ? 141.931 160.258 171.805 1.00 135.08 ? 35  GLY A O   1 
ATOM   229  N  N   . PHE A 1 36  ? 141.050 160.531 169.753 1.00 140.03 ? 36  PHE A N   1 
ATOM   230  C  CA  . PHE A 1 36  ? 140.560 159.164 169.696 1.00 140.03 ? 36  PHE A CA  1 
ATOM   231  C  C   . PHE A 1 36  ? 141.717 158.193 169.476 1.00 140.03 ? 36  PHE A C   1 
ATOM   232  O  O   . PHE A 1 36  ? 142.784 158.554 168.971 1.00 140.03 ? 36  PHE A O   1 
ATOM   233  C  CB  . PHE A 1 36  ? 139.515 159.014 168.592 1.00 140.03 ? 36  PHE A CB  1 
ATOM   234  C  CG  . PHE A 1 36  ? 138.247 159.772 168.857 1.00 140.03 ? 36  PHE A CG  1 
ATOM   235  C  CD1 . PHE A 1 36  ? 137.271 159.244 169.686 1.00 140.03 ? 36  PHE A CD1 1 
ATOM   236  C  CD2 . PHE A 1 36  ? 138.034 161.015 168.283 1.00 140.03 ? 36  PHE A CD2 1 
ATOM   237  C  CE1 . PHE A 1 36  ? 136.103 159.940 169.936 1.00 140.03 ? 36  PHE A CE1 1 
ATOM   238  C  CE2 . PHE A 1 36  ? 136.868 161.716 168.529 1.00 140.03 ? 36  PHE A CE2 1 
ATOM   239  C  CZ  . PHE A 1 36  ? 135.902 161.178 169.356 1.00 140.03 ? 36  PHE A CZ  1 
ATOM   240  N  N   . ASN A 1 37  ? 141.493 156.941 169.870 1.00 142.63 ? 37  ASN A N   1 
ATOM   241  C  CA  . ASN A 1 37  ? 142.522 155.907 169.869 1.00 142.63 ? 37  ASN A CA  1 
ATOM   242  C  C   . ASN A 1 37  ? 142.283 154.847 168.796 1.00 142.63 ? 37  ASN A C   1 
ATOM   243  O  O   . ASN A 1 37  ? 142.431 153.651 169.051 1.00 142.63 ? 37  ASN A O   1 
ATOM   244  C  CB  . ASN A 1 37  ? 142.633 155.239 171.239 1.00 142.63 ? 37  ASN A CB  1 
ATOM   245  C  CG  . ASN A 1 37  ? 142.775 156.235 172.378 1.00 142.63 ? 37  ASN A CG  1 
ATOM   246  O  OD1 . ASN A 1 37  ? 142.785 157.445 172.169 1.00 142.63 ? 37  ASN A OD1 1 
ATOM   247  N  ND2 . ASN A 1 37  ? 142.909 155.721 173.594 1.00 142.63 ? 37  ASN A ND2 1 
ATOM   248  N  N   . GLU A 1 38  ? 141.894 155.264 167.592 1.00 140.19 ? 38  GLU A N   1 
ATOM   249  C  CA  . GLU A 1 38  ? 141.649 154.307 166.510 1.00 140.19 ? 38  GLU A CA  1 
ATOM   250  C  C   . GLU A 1 38  ? 142.947 153.629 166.078 1.00 140.19 ? 38  GLU A C   1 
ATOM   251  O  O   . GLU A 1 38  ? 144.033 154.189 166.229 1.00 140.19 ? 38  GLU A O   1 
ATOM   252  C  CB  . GLU A 1 38  ? 140.993 154.972 165.284 1.00 140.19 ? 38  GLU A CB  1 
ATOM   253  C  CG  . GLU A 1 38  ? 141.773 156.092 164.552 1.00 140.19 ? 38  GLU A CG  1 
ATOM   254  C  CD  . GLU A 1 38  ? 142.023 157.370 165.349 1.00 140.19 ? 38  GLU A CD  1 
ATOM   255  O  OE1 . GLU A 1 38  ? 142.485 158.354 164.734 1.00 140.19 ? 38  GLU A OE1 1 
ATOM   256  O  OE2 . GLU A 1 38  ? 141.733 157.421 166.558 1.00 140.19 ? 38  GLU A OE2 1 
ATOM   257  N  N   . ASP A 1 45  ? 144.042 154.689 151.366 1.00 124.51 ? 45  ASP A N   1 
ATOM   258  C  CA  . ASP A 1 45  ? 144.431 154.640 149.962 1.00 124.51 ? 45  ASP A CA  1 
ATOM   259  C  C   . ASP A 1 45  ? 143.258 154.983 149.049 1.00 124.51 ? 45  ASP A C   1 
ATOM   260  O  O   . ASP A 1 45  ? 142.195 154.368 149.144 1.00 124.51 ? 45  ASP A O   1 
ATOM   261  C  CB  . ASP A 1 45  ? 144.982 153.258 149.604 1.00 124.51 ? 45  ASP A CB  1 
ATOM   262  C  CG  . ASP A 1 45  ? 145.482 153.182 148.175 1.00 124.51 ? 45  ASP A CG  1 
ATOM   263  O  OD1 . ASP A 1 45  ? 146.439 153.911 147.838 1.00 124.51 ? 45  ASP A OD1 1 
ATOM   264  O  OD2 . ASP A 1 45  ? 144.916 152.396 147.386 1.00 124.51 ? 45  ASP A OD2 1 
ATOM   265  N  N   . PRO A 1 46  ? 143.448 155.976 148.179 1.00 123.30 ? 46  PRO A N   1 
ATOM   266  C  CA  . PRO A 1 46  ? 142.406 156.304 147.200 1.00 123.30 ? 46  PRO A CA  1 
ATOM   267  C  C   . PRO A 1 46  ? 142.191 155.162 146.219 1.00 123.30 ? 46  PRO A C   1 
ATOM   268  O  O   . PRO A 1 46  ? 143.117 154.423 145.877 1.00 123.30 ? 46  PRO A O   1 
ATOM   269  C  CB  . PRO A 1 46  ? 142.957 157.551 146.496 1.00 123.30 ? 46  PRO A CB  1 
ATOM   270  C  CG  . PRO A 1 46  ? 144.007 158.092 147.418 1.00 123.30 ? 46  PRO A CG  1 
ATOM   271  C  CD  . PRO A 1 46  ? 144.592 156.898 148.101 1.00 123.30 ? 46  PRO A CD  1 
ATOM   272  N  N   . LEU A 1 47  ? 140.941 155.020 145.769 1.00 119.73 ? 47  LEU A N   1 
ATOM   273  C  CA  . LEU A 1 47  ? 140.607 153.935 144.852 1.00 119.73 ? 47  LEU A CA  1 
ATOM   274  C  C   . LEU A 1 47  ? 141.195 154.161 143.465 1.00 119.73 ? 47  LEU A C   1 
ATOM   275  O  O   . LEU A 1 47  ? 141.587 153.196 142.798 1.00 119.73 ? 47  LEU A O   1 
ATOM   276  C  CB  . LEU A 1 47  ? 139.090 153.764 144.770 1.00 119.73 ? 47  LEU A CB  1 
ATOM   277  C  CG  . LEU A 1 47  ? 138.518 152.588 145.565 1.00 119.73 ? 47  LEU A CG  1 
ATOM   278  C  CD1 . LEU A 1 47  ? 139.098 151.274 145.067 1.00 119.73 ? 47  LEU A CD1 1 
ATOM   279  C  CD2 . LEU A 1 47  ? 138.780 152.759 147.054 1.00 119.73 ? 47  LEU A CD2 1 
ATOM   280  N  N   . TRP A 1 48  ? 141.260 155.415 143.010 1.00 118.42 ? 48  TRP A N   1 
ATOM   281  C  CA  . TRP A 1 48  ? 141.902 155.699 141.731 1.00 118.42 ? 48  TRP A CA  1 
ATOM   282  C  C   . TRP A 1 48  ? 143.402 155.439 141.788 1.00 118.42 ? 48  TRP A C   1 
ATOM   283  O  O   . TRP A 1 48  ? 143.991 154.991 140.796 1.00 118.42 ? 48  TRP A O   1 
ATOM   284  C  CB  . TRP A 1 48  ? 141.618 157.139 141.301 1.00 118.42 ? 48  TRP A CB  1 
ATOM   285  C  CG  . TRP A 1 48  ? 141.755 158.146 142.399 1.00 118.42 ? 48  TRP A CG  1 
ATOM   286  C  CD1 . TRP A 1 48  ? 142.879 158.840 142.741 1.00 118.42 ? 48  TRP A CD1 1 
ATOM   287  C  CD2 . TRP A 1 48  ? 140.726 158.586 143.294 1.00 118.42 ? 48  TRP A CD2 1 
ATOM   288  N  NE1 . TRP A 1 48  ? 142.616 159.679 143.797 1.00 118.42 ? 48  TRP A NE1 1 
ATOM   289  C  CE2 . TRP A 1 48  ? 141.300 159.542 144.154 1.00 118.42 ? 48  TRP A CE2 1 
ATOM   290  C  CE3 . TRP A 1 48  ? 139.375 158.260 143.453 1.00 118.42 ? 48  TRP A CE3 1 
ATOM   291  C  CZ2 . TRP A 1 48  ? 140.572 160.176 145.159 1.00 118.42 ? 48  TRP A CZ2 1 
ATOM   292  C  CZ3 . TRP A 1 48  ? 138.653 158.891 144.451 1.00 118.42 ? 48  TRP A CZ3 1 
ATOM   293  C  CH2 . TRP A 1 48  ? 139.253 159.838 145.291 1.00 118.42 ? 48  TRP A CH2 1 
ATOM   294  N  N   . LYS A 1 49  ? 144.034 155.700 142.935 1.00 120.98 ? 49  LYS A N   1 
ATOM   295  C  CA  . LYS A 1 49  ? 145.439 155.343 143.103 1.00 120.98 ? 49  LYS A CA  1 
ATOM   296  C  C   . LYS A 1 49  ? 145.630 153.831 143.054 1.00 120.98 ? 49  LYS A C   1 
ATOM   297  O  O   . LYS A 1 49  ? 146.613 153.339 142.487 1.00 120.98 ? 49  LYS A O   1 
ATOM   298  C  CB  . LYS A 1 49  ? 145.971 155.913 144.417 1.00 120.98 ? 49  LYS A CB  1 
ATOM   299  C  CG  . LYS A 1 49  ? 147.475 156.125 144.435 1.00 120.98 ? 49  LYS A CG  1 
ATOM   300  C  CD  . LYS A 1 49  ? 147.846 157.472 143.837 1.00 120.98 ? 49  LYS A CD  1 
ATOM   301  C  CE  . LYS A 1 49  ? 147.384 158.617 144.725 1.00 120.98 ? 49  LYS A CE  1 
ATOM   302  N  NZ  . LYS A 1 49  ? 147.768 159.942 144.165 1.00 120.98 ? 49  LYS A NZ  1 
ATOM   303  N  N   . LEU A 1 50  ? 144.696 153.078 143.643 1.00 118.77 ? 50  LEU A N   1 
ATOM   304  C  CA  . LEU A 1 50  ? 144.743 151.622 143.548 1.00 118.77 ? 50  LEU A CA  1 
ATOM   305  C  C   . LEU A 1 50  ? 144.579 151.158 142.105 1.00 118.77 ? 50  LEU A C   1 
ATOM   306  O  O   . LEU A 1 50  ? 145.264 150.227 141.662 1.00 118.77 ? 50  LEU A O   1 
ATOM   307  C  CB  . LEU A 1 50  ? 143.663 151.006 144.439 1.00 118.77 ? 50  LEU A CB  1 
ATOM   308  C  CG  . LEU A 1 50  ? 143.466 149.491 144.352 1.00 118.77 ? 50  LEU A CG  1 
ATOM   309  C  CD1 . LEU A 1 50  ? 144.723 148.758 144.795 1.00 118.77 ? 50  LEU A CD1 1 
ATOM   310  C  CD2 . LEU A 1 50  ? 142.268 149.057 145.181 1.00 118.77 ? 50  LEU A CD2 1 
ATOM   311  N  N   . PHE A 1 51  ? 143.677 151.799 141.357 1.00 112.38 ? 51  PHE A N   1 
ATOM   312  C  CA  . PHE A 1 51  ? 143.504 151.474 139.943 1.00 112.38 ? 51  PHE A CA  1 
ATOM   313  C  C   . PHE A 1 51  ? 144.776 151.762 139.155 1.00 112.38 ? 51  PHE A C   1 
ATOM   314  O  O   . PHE A 1 51  ? 145.140 151.005 138.247 1.00 112.38 ? 51  PHE A O   1 
ATOM   315  C  CB  . PHE A 1 51  ? 142.310 152.252 139.379 1.00 112.38 ? 51  PHE A CB  1 
ATOM   316  C  CG  . PHE A 1 51  ? 142.526 152.801 137.991 1.00 112.38 ? 51  PHE A CG  1 
ATOM   317  C  CD1 . PHE A 1 51  ? 142.375 151.991 136.875 1.00 112.38 ? 51  PHE A CD1 1 
ATOM   318  C  CD2 . PHE A 1 51  ? 142.853 154.136 137.804 1.00 112.38 ? 51  PHE A CD2 1 
ATOM   319  C  CE1 . PHE A 1 51  ? 142.568 152.498 135.602 1.00 112.38 ? 51  PHE A CE1 1 
ATOM   320  C  CE2 . PHE A 1 51  ? 143.047 154.648 136.534 1.00 112.38 ? 51  PHE A CE2 1 
ATOM   321  C  CZ  . PHE A 1 51  ? 142.903 153.828 135.432 1.00 112.38 ? 51  PHE A CZ  1 
ATOM   322  N  N   . LEU A 1 52  ? 145.458 152.861 139.484 1.00 111.83 ? 52  LEU A N   1 
ATOM   323  C  CA  . LEU A 1 52  ? 146.734 153.169 138.846 1.00 111.83 ? 52  LEU A CA  1 
ATOM   324  C  C   . LEU A 1 52  ? 147.798 152.134 139.197 1.00 111.83 ? 52  LEU A C   1 
ATOM   325  O  O   . LEU A 1 52  ? 148.609 151.756 138.343 1.00 111.83 ? 52  LEU A O   1 
ATOM   326  C  CB  . LEU A 1 52  ? 147.195 154.569 139.249 1.00 111.83 ? 52  LEU A CB  1 
ATOM   327  C  CG  . LEU A 1 52  ? 148.342 155.180 138.442 1.00 111.83 ? 52  LEU A CG  1 
ATOM   328  C  CD1 . LEU A 1 52  ? 147.885 155.529 137.034 1.00 111.83 ? 52  LEU A CD1 1 
ATOM   329  C  CD2 . LEU A 1 52  ? 148.902 156.406 139.148 1.00 111.83 ? 52  LEU A CD2 1 
ATOM   330  N  N   . GLU A 1 53  ? 147.813 151.665 140.444 1.00 114.66 ? 53  GLU A N   1 
ATOM   331  C  CA  . GLU A 1 53  ? 148.853 150.757 140.911 1.00 114.66 ? 53  GLU A CA  1 
ATOM   332  C  C   . GLU A 1 53  ? 148.563 149.288 140.617 1.00 114.66 ? 53  GLU A C   1 
ATOM   333  O  O   . GLU A 1 53  ? 149.439 148.446 140.847 1.00 114.66 ? 53  GLU A O   1 
ATOM   334  C  CB  . GLU A 1 53  ? 149.078 150.940 142.417 1.00 114.66 ? 53  GLU A CB  1 
ATOM   335  C  CG  . GLU A 1 53  ? 148.147 150.127 143.303 1.00 114.66 ? 53  GLU A CG  1 
ATOM   336  C  CD  . GLU A 1 53  ? 148.606 150.089 144.747 1.00 114.66 ? 53  GLU A CD  1 
ATOM   337  O  OE1 . GLU A 1 53  ? 149.665 150.677 145.051 1.00 114.66 ? 53  GLU A OE1 1 
ATOM   338  O  OE2 . GLU A 1 53  ? 147.909 149.469 145.578 1.00 114.66 ? 53  GLU A OE2 1 
ATOM   339  N  N   . THR A 1 54  ? 147.376 148.955 140.103 1.00 103.63 ? 54  THR A N   1 
ATOM   340  C  CA  . THR A 1 54  ? 147.043 147.575 139.760 1.00 103.63 ? 54  THR A CA  1 
ATOM   341  C  C   . THR A 1 54  ? 147.427 147.212 138.329 1.00 103.63 ? 54  THR A C   1 
ATOM   342  O  O   . THR A 1 54  ? 146.795 146.336 137.723 1.00 103.63 ? 54  THR A O   1 
ATOM   343  C  CB  . THR A 1 54  ? 145.555 147.308 139.991 1.00 103.63 ? 54  THR A CB  1 
ATOM   344  O  OG1 . THR A 1 54  ? 144.786 148.436 139.556 1.00 103.63 ? 54  THR A OG1 1 
ATOM   345  C  CG2 . THR A 1 54  ? 145.278 147.018 141.461 1.00 103.63 ? 54  THR A CG2 1 
ATOM   346  N  N   . PHE A 1 55  ? 148.472 147.815 137.767 1.00 100.97 ? 55  PHE A N   1 
ATOM   347  C  CA  . PHE A 1 55  ? 148.841 147.380 136.393 1.00 100.97 ? 55  PHE A CA  1 
ATOM   348  C  C   . PHE A 1 55  ? 149.956 146.334 136.454 1.00 100.97 ? 55  PHE A C   1 
ATOM   349  O  O   . PHE A 1 55  ? 150.425 145.912 135.384 1.00 100.97 ? 55  PHE A O   1 
ATOM   350  C  CB  . PHE A 1 55  ? 149.241 148.583 135.537 1.00 100.97 ? 55  PHE A CB  1 
ATOM   351  C  CG  . PHE A 1 55  ? 148.076 149.337 134.949 1.00 100.97 ? 55  PHE A CG  1 
ATOM   352  C  CD1 . PHE A 1 55  ? 147.731 149.182 133.617 1.00 100.97 ? 55  PHE A CD1 1 
ATOM   353  C  CD2 . PHE A 1 55  ? 147.319 150.196 135.730 1.00 100.97 ? 55  PHE A CD2 1 
ATOM   354  C  CE1 . PHE A 1 55  ? 146.659 149.873 133.077 1.00 100.97 ? 55  PHE A CE1 1 
ATOM   355  C  CE2 . PHE A 1 55  ? 146.247 150.888 135.189 1.00 100.97 ? 55  PHE A CE2 1 
ATOM   356  C  CZ  . PHE A 1 55  ? 145.919 150.725 133.864 1.00 100.97 ? 55  PHE A CZ  1 
ATOM   357  N  N   . LYS A 1 56  ? 150.348 145.916 137.659 1.00 97.96  ? 56  LYS A N   1 
ATOM   358  C  CA  . LYS A 1 56  ? 151.443 144.967 137.818 1.00 97.96  ? 56  LYS A CA  1 
ATOM   359  C  C   . LYS A 1 56  ? 151.144 143.594 137.223 1.00 97.96  ? 56  LYS A C   1 
ATOM   360  O  O   . LYS A 1 56  ? 152.067 142.781 137.101 1.00 97.96  ? 56  LYS A O   1 
ATOM   361  C  CB  . LYS A 1 56  ? 151.790 144.828 139.305 1.00 97.96  ? 56  LYS A CB  1 
ATOM   362  C  CG  . LYS A 1 56  ? 153.220 144.377 139.594 1.00 97.96  ? 56  LYS A CG  1 
ATOM   363  C  CD  . LYS A 1 56  ? 154.221 145.058 138.673 1.00 97.96  ? 56  LYS A CD  1 
ATOM   364  C  CE  . LYS A 1 56  ? 155.604 144.441 138.808 1.00 97.96  ? 56  LYS A CE  1 
ATOM   365  N  NZ  . LYS A 1 56  ? 156.564 145.015 137.826 1.00 97.96  ? 56  LYS A NZ  1 
ATOM   366  N  N   . ASP A 1 57  ? 149.899 143.317 136.854 1.00 91.34  ? 57  ASP A N   1 
ATOM   367  C  CA  . ASP A 1 57  ? 149.547 142.011 136.302 1.00 91.34  ? 57  ASP A CA  1 
ATOM   368  C  C   . ASP A 1 57  ? 150.221 141.814 134.950 1.00 91.34  ? 57  ASP A C   1 
ATOM   369  O  O   . ASP A 1 57  ? 150.050 142.656 134.058 1.00 91.34  ? 57  ASP A O   1 
ATOM   370  C  CB  . ASP A 1 57  ? 148.033 141.886 136.165 1.00 91.34  ? 57  ASP A CB  1 
ATOM   371  C  CG  . ASP A 1 57  ? 147.286 142.609 137.268 1.00 91.34  ? 57  ASP A CG  1 
ATOM   372  O  OD1 . ASP A 1 57  ? 146.509 143.534 136.952 1.00 91.34  ? 57  ASP A OD1 1 
ATOM   373  O  OD2 . ASP A 1 57  ? 147.474 142.253 138.450 1.00 91.34  ? 57  ASP A OD2 1 
ATOM   374  N  N   . PRO A 1 58  ? 151.004 140.744 134.760 1.00 83.85  ? 58  PRO A N   1 
ATOM   375  C  CA  . PRO A 1 58  ? 151.706 140.564 133.475 1.00 83.85  ? 58  PRO A CA  1 
ATOM   376  C  C   . PRO A 1 58  ? 150.774 140.418 132.285 1.00 83.85  ? 58  PRO A C   1 
ATOM   377  O  O   . PRO A 1 58  ? 151.103 140.883 131.184 1.00 83.85  ? 58  PRO A O   1 
ATOM   378  C  CB  . PRO A 1 58  ? 152.536 139.293 133.709 1.00 83.85  ? 58  PRO A CB  1 
ATOM   379  C  CG  . PRO A 1 58  ? 151.832 138.573 134.811 1.00 83.85  ? 58  PRO A CG  1 
ATOM   380  C  CD  . PRO A 1 58  ? 151.260 139.638 135.696 1.00 83.85  ? 58  PRO A CD  1 
ATOM   381  N  N   . MET A 1 59  ? 149.615 139.783 132.477 1.00 77.93  ? 59  MET A N   1 
ATOM   382  C  CA  . MET A 1 59  ? 148.617 139.727 131.415 1.00 77.93  ? 59  MET A CA  1 
ATOM   383  C  C   . MET A 1 59  ? 148.114 141.124 131.068 1.00 77.93  ? 59  MET A C   1 
ATOM   384  O  O   . MET A 1 59  ? 147.960 141.466 129.889 1.00 77.93  ? 59  MET A O   1 
ATOM   385  C  CB  . MET A 1 59  ? 147.463 138.808 131.828 1.00 77.93  ? 59  MET A CB  1 
ATOM   386  C  CG  . MET A 1 59  ? 146.854 139.111 133.193 1.00 77.93  ? 59  MET A CG  1 
ATOM   387  S  SD  . MET A 1 59  ? 147.882 138.579 134.576 1.00 77.93  ? 59  MET A SD  1 
ATOM   388  C  CE  . MET A 1 59  ? 147.342 136.883 134.762 1.00 77.93  ? 59  MET A CE  1 
ATOM   389  N  N   . VAL A 1 60  ? 147.894 141.959 132.085 1.00 83.10  ? 60  VAL A N   1 
ATOM   390  C  CA  . VAL A 1 60  ? 147.477 143.337 131.850 1.00 83.10  ? 60  VAL A CA  1 
ATOM   391  C  C   . VAL A 1 60  ? 148.589 144.113 131.151 1.00 83.10  ? 60  VAL A C   1 
ATOM   392  O  O   . VAL A 1 60  ? 148.329 144.943 130.273 1.00 83.10  ? 60  VAL A O   1 
ATOM   393  C  CB  . VAL A 1 60  ? 147.049 143.984 133.183 1.00 83.10  ? 60  VAL A CB  1 
ATOM   394  C  CG1 . VAL A 1 60  ? 147.265 145.487 133.180 1.00 83.10  ? 60  VAL A CG1 1 
ATOM   395  C  CG2 . VAL A 1 60  ? 145.594 143.653 133.483 1.00 83.10  ? 60  VAL A CG2 1 
ATOM   396  N  N   . ILE A 1 61  ? 149.846 143.815 131.491 1.00 85.83  ? 61  ILE A N   1 
ATOM   397  C  CA  . ILE A 1 61  ? 150.981 144.502 130.875 1.00 85.83  ? 61  ILE A CA  1 
ATOM   398  C  C   . ILE A 1 61  ? 151.077 144.168 129.388 1.00 85.83  ? 61  ILE A C   1 
ATOM   399  O  O   . ILE A 1 61  ? 151.227 145.062 128.542 1.00 85.83  ? 61  ILE A O   1 
ATOM   400  C  CB  . ILE A 1 61  ? 152.283 144.152 131.619 1.00 85.83  ? 61  ILE A CB  1 
ATOM   401  C  CG1 . ILE A 1 61  ? 152.363 144.914 132.941 1.00 85.83  ? 61  ILE A CG1 1 
ATOM   402  C  CG2 . ILE A 1 61  ? 153.502 144.459 130.761 1.00 85.83  ? 61  ILE A CG2 1 
ATOM   403  C  CD1 . ILE A 1 61  ? 152.982 144.118 134.069 1.00 85.83  ? 61  ILE A CD1 1 
ATOM   404  N  N   . VAL A 1 62  ? 151.000 142.878 129.043 1.00 84.08  ? 62  VAL A N   1 
ATOM   405  C  CA  . VAL A 1 62  ? 151.111 142.506 127.635 1.00 84.08  ? 62  VAL A CA  1 
ATOM   406  C  C   . VAL A 1 62  ? 149.892 142.996 126.859 1.00 84.08  ? 62  VAL A C   1 
ATOM   407  O  O   . VAL A 1 62  ? 150.004 143.414 125.698 1.00 84.08  ? 62  VAL A O   1 
ATOM   408  C  CB  . VAL A 1 62  ? 151.341 140.988 127.472 1.00 84.08  ? 62  VAL A CB  1 
ATOM   409  C  CG1 . VAL A 1 62  ? 150.236 140.174 128.110 1.00 84.08  ? 62  VAL A CG1 1 
ATOM   410  C  CG2 . VAL A 1 62  ? 151.507 140.617 126.000 1.00 84.08  ? 62  VAL A CG2 1 
ATOM   411  N  N   . LEU A 1 63  ? 148.717 143.018 127.493 1.00 80.45  ? 63  LEU A N   1 
ATOM   412  C  CA  . LEU A 1 63  ? 147.565 143.543 126.776 1.00 80.45  ? 63  LEU A CA  1 
ATOM   413  C  C   . LEU A 1 63  ? 147.651 145.049 126.589 1.00 80.45  ? 63  LEU A C   1 
ATOM   414  O  O   . LEU A 1 63  ? 147.176 145.566 125.577 1.00 80.45  ? 63  LEU A O   1 
ATOM   415  C  CB  . LEU A 1 63  ? 146.268 143.197 127.488 1.00 80.45  ? 63  LEU A CB  1 
ATOM   416  C  CG  . LEU A 1 63  ? 145.855 141.735 127.439 1.00 80.45  ? 63  LEU A CG  1 
ATOM   417  C  CD1 . LEU A 1 63  ? 144.408 141.669 127.835 1.00 80.45  ? 63  LEU A CD1 1 
ATOM   418  C  CD2 . LEU A 1 63  ? 146.131 141.080 126.099 1.00 80.45  ? 63  LEU A CD2 1 
ATOM   419  N  N   . VAL A 1 64  ? 148.245 145.771 127.538 1.00 83.77  ? 64  VAL A N   1 
ATOM   420  C  CA  . VAL A 1 64  ? 148.333 147.216 127.371 1.00 83.77  ? 64  VAL A CA  1 
ATOM   421  C  C   . VAL A 1 64  ? 149.409 147.577 126.351 1.00 83.77  ? 64  VAL A C   1 
ATOM   422  O  O   . VAL A 1 64  ? 149.258 148.561 125.614 1.00 83.77  ? 64  VAL A O   1 
ATOM   423  C  CB  . VAL A 1 64  ? 148.538 147.915 128.732 1.00 83.77  ? 64  VAL A CB  1 
ATOM   424  C  CG1 . VAL A 1 64  ? 148.757 149.417 128.594 1.00 83.77  ? 64  VAL A CG1 1 
ATOM   425  C  CG2 . VAL A 1 64  ? 147.359 147.630 129.647 1.00 83.77  ? 64  VAL A CG2 1 
ATOM   426  N  N   . ILE A 1 65  ? 150.478 146.779 126.238 1.00 87.74  ? 65  ILE A N   1 
ATOM   427  C  CA  . ILE A 1 65  ? 151.429 147.068 125.169 1.00 87.74  ? 65  ILE A CA  1 
ATOM   428  C  C   . ILE A 1 65  ? 150.812 146.716 123.817 1.00 87.74  ? 65  ILE A C   1 
ATOM   429  O  O   . ILE A 1 65  ? 151.014 147.443 122.833 1.00 87.74  ? 65  ILE A O   1 
ATOM   430  C  CB  . ILE A 1 65  ? 152.797 146.384 125.401 1.00 87.74  ? 65  ILE A CB  1 
ATOM   431  C  CG1 . ILE A 1 65  ? 153.829 146.896 124.393 1.00 87.74  ? 65  ILE A CG1 1 
ATOM   432  C  CG2 . ILE A 1 65  ? 152.726 144.878 125.301 1.00 87.74  ? 65  ILE A CG2 1 
ATOM   433  C  CD1 . ILE A 1 65  ? 155.259 146.823 124.890 1.00 87.74  ? 65  ILE A CD1 1 
ATOM   434  N  N   . ALA A 1 66  ? 150.002 145.649 123.758 1.00 85.45  ? 66  ALA A N   1 
ATOM   435  C  CA  . ALA A 1 66  ? 149.276 145.335 122.530 1.00 85.45  ? 66  ALA A CA  1 
ATOM   436  C  C   . ALA A 1 66  ? 148.294 146.444 122.170 1.00 85.45  ? 66  ALA A C   1 
ATOM   437  O  O   . ALA A 1 66  ? 148.165 146.812 120.998 1.00 85.45  ? 66  ALA A O   1 
ATOM   438  C  CB  . ALA A 1 66  ? 148.546 144.000 122.676 1.00 85.45  ? 66  ALA A CB  1 
ATOM   439  N  N   . ALA A 1 67  ? 147.602 146.994 123.171 1.00 86.58  ? 67  ALA A N   1 
ATOM   440  C  CA  . ALA A 1 67  ? 146.662 148.084 122.934 1.00 86.58  ? 67  ALA A CA  1 
ATOM   441  C  C   . ALA A 1 67  ? 147.375 149.328 122.422 1.00 86.58  ? 67  ALA A C   1 
ATOM   442  O  O   . ALA A 1 67  ? 146.881 150.006 121.514 1.00 86.58  ? 67  ALA A O   1 
ATOM   443  C  CB  . ALA A 1 67  ? 145.893 148.403 124.216 1.00 86.58  ? 67  ALA A CB  1 
ATOM   444  N  N   . LEU A 1 68  ? 148.548 149.643 122.980 1.00 93.51  ? 68  LEU A N   1 
ATOM   445  C  CA  . LEU A 1 68  ? 149.236 150.849 122.528 1.00 93.51  ? 68  LEU A CA  1 
ATOM   446  C  C   . LEU A 1 68  ? 149.799 150.677 121.118 1.00 93.51  ? 68  LEU A C   1 
ATOM   447  O  O   . LEU A 1 68  ? 149.767 151.624 120.322 1.00 93.51  ? 68  LEU A O   1 
ATOM   448  C  CB  . LEU A 1 68  ? 150.330 151.266 123.515 1.00 93.51  ? 68  LEU A CB  1 
ATOM   449  C  CG  . LEU A 1 68  ? 151.627 150.493 123.749 1.00 93.51  ? 68  LEU A CG  1 
ATOM   450  C  CD1 . LEU A 1 68  ? 152.748 150.953 122.822 1.00 93.51  ? 68  LEU A CD1 1 
ATOM   451  C  CD2 . LEU A 1 68  ? 152.045 150.652 125.202 1.00 93.51  ? 68  LEU A CD2 1 
ATOM   452  N  N   . VAL A 1 69  ? 150.307 149.489 120.767 1.00 89.49  ? 69  VAL A N   1 
ATOM   453  C  CA  . VAL A 1 69  ? 150.767 149.341 119.385 1.00 89.49  ? 69  VAL A CA  1 
ATOM   454  C  C   . VAL A 1 69  ? 149.579 149.337 118.434 1.00 89.49  ? 69  VAL A C   1 
ATOM   455  O  O   . VAL A 1 69  ? 149.625 149.970 117.379 1.00 89.49  ? 69  VAL A O   1 
ATOM   456  C  CB  . VAL A 1 69  ? 151.663 148.100 119.181 1.00 89.49  ? 69  VAL A CB  1 
ATOM   457  C  CG1 . VAL A 1 69  ? 151.087 146.854 119.794 1.00 89.49  ? 69  VAL A CG1 1 
ATOM   458  C  CG2 . VAL A 1 69  ? 151.968 147.878 117.707 1.00 89.49  ? 69  VAL A CG2 1 
ATOM   459  N  N   . GLN A 1 70  ? 148.470 148.697 118.816 1.00 84.69  ? 70  GLN A N   1 
ATOM   460  C  CA  . GLN A 1 70  ? 147.281 148.730 117.971 1.00 84.69  ? 70  GLN A CA  1 
ATOM   461  C  C   . GLN A 1 70  ? 146.717 150.136 117.840 1.00 84.69  ? 70  GLN A C   1 
ATOM   462  O  O   . GLN A 1 70  ? 146.032 150.430 116.852 1.00 84.69  ? 70  GLN A O   1 
ATOM   463  C  CB  . GLN A 1 70  ? 146.212 147.784 118.525 1.00 84.69  ? 70  GLN A CB  1 
ATOM   464  C  CG  . GLN A 1 70  ? 146.542 146.280 118.499 1.00 84.69  ? 70  GLN A CG  1 
ATOM   465  C  CD  . GLN A 1 70  ? 146.806 145.706 117.110 1.00 84.69  ? 70  GLN A CD  1 
ATOM   466  O  OE1 . GLN A 1 70  ? 146.132 146.048 116.129 1.00 84.69  ? 70  GLN A OE1 1 
ATOM   467  N  NE2 . GLN A 1 70  ? 147.795 144.836 117.021 1.00 84.69  ? 70  GLN A NE2 1 
ATOM   468  N  N   . LEU A 1 71  ? 146.996 151.006 118.813 1.00 90.58  ? 71  LEU A N   1 
ATOM   469  C  CA  . LEU A 1 71  ? 146.669 152.415 118.663 1.00 90.58  ? 71  LEU A CA  1 
ATOM   470  C  C   . LEU A 1 71  ? 147.627 153.105 117.699 1.00 90.58  ? 71  LEU A C   1 
ATOM   471  O  O   . LEU A 1 71  ? 147.210 153.978 116.929 1.00 90.58  ? 71  LEU A O   1 
ATOM   472  C  CB  . LEU A 1 71  ? 146.685 153.097 120.029 1.00 90.58  ? 71  LEU A CB  1 
ATOM   473  C  CG  . LEU A 1 71  ? 146.485 154.614 120.097 1.00 90.58  ? 71  LEU A CG  1 
ATOM   474  C  CD1 . LEU A 1 71  ? 145.343 154.943 121.040 1.00 90.58  ? 71  LEU A CD1 1 
ATOM   475  C  CD2 . LEU A 1 71  ? 147.764 155.313 120.542 1.00 90.58  ? 71  LEU A CD2 1 
ATOM   476  N  N   . VAL A 1 72  ? 148.915 152.736 117.726 1.00 91.39  ? 72  VAL A N   1 
ATOM   477  C  CA  . VAL A 1 72  ? 149.902 153.514 116.977 1.00 91.39  ? 72  VAL A CA  1 
ATOM   478  C  C   . VAL A 1 72  ? 149.831 153.266 115.467 1.00 91.39  ? 72  VAL A C   1 
ATOM   479  O  O   . VAL A 1 72  ? 150.353 154.080 114.697 1.00 91.39  ? 72  VAL A O   1 
ATOM   480  C  CB  . VAL A 1 72  ? 151.335 153.264 117.499 1.00 91.39  ? 72  VAL A CB  1 
ATOM   481  C  CG1 . VAL A 1 72  ? 151.953 152.013 116.885 1.00 91.39  ? 72  VAL A CG1 1 
ATOM   482  C  CG2 . VAL A 1 72  ? 152.212 154.492 117.289 1.00 91.39  ? 72  VAL A CG2 1 
ATOM   483  N  N   . LEU A 1 73  ? 149.194 152.187 115.001 1.00 85.16  ? 73  LEU A N   1 
ATOM   484  C  CA  . LEU A 1 73  ? 148.960 152.064 113.562 1.00 85.16  ? 73  LEU A CA  1 
ATOM   485  C  C   . LEU A 1 73  ? 147.742 152.845 113.078 1.00 85.16  ? 73  LEU A C   1 
ATOM   486  O  O   . LEU A 1 73  ? 147.336 152.669 111.923 1.00 85.16  ? 73  LEU A O   1 
ATOM   487  C  CB  . LEU A 1 73  ? 148.808 150.602 113.125 1.00 85.16  ? 73  LEU A CB  1 
ATOM   488  C  CG  . LEU A 1 73  ? 149.949 149.579 113.194 1.00 85.16  ? 73  LEU A CG  1 
ATOM   489  C  CD1 . LEU A 1 73  ? 151.282 150.192 112.763 1.00 85.16  ? 73  LEU A CD1 1 
ATOM   490  C  CD2 . LEU A 1 73  ? 150.059 148.848 114.522 1.00 85.16  ? 73  LEU A CD2 1 
ATOM   491  N  N   . GLY A 1 74  ? 147.154 153.687 113.919 1.00 90.27  ? 74  GLY A N   1 
ATOM   492  C  CA  . GLY A 1 74  ? 146.042 154.525 113.502 1.00 90.27  ? 74  GLY A CA  1 
ATOM   493  C  C   . GLY A 1 74  ? 144.760 153.784 113.188 1.00 90.27  ? 74  GLY A C   1 
ATOM   494  O  O   . GLY A 1 74  ? 144.046 154.160 112.251 1.00 90.27  ? 74  GLY A O   1 
ATOM   495  N  N   . GLU A 1 75  ? 144.455 152.733 113.943 1.00 85.01  ? 75  GLU A N   1 
ATOM   496  C  CA  . GLU A 1 75  ? 143.181 152.033 113.849 1.00 85.01  ? 75  GLU A CA  1 
ATOM   497  C  C   . GLU A 1 75  ? 142.444 152.235 115.163 1.00 85.01  ? 75  GLU A C   1 
ATOM   498  O  O   . GLU A 1 75  ? 142.974 151.910 116.232 1.00 85.01  ? 75  GLU A O   1 
ATOM   499  C  CB  . GLU A 1 75  ? 143.381 150.549 113.547 1.00 85.01  ? 75  GLU A CB  1 
ATOM   500  C  CG  . GLU A 1 75  ? 143.297 150.210 112.067 1.00 85.01  ? 75  GLU A CG  1 
ATOM   501  C  CD  . GLU A 1 75  ? 141.935 150.518 111.473 1.00 85.01  ? 75  GLU A CD  1 
ATOM   502  O  OE1 . GLU A 1 75  ? 140.916 150.236 112.137 1.00 85.01  ? 75  GLU A OE1 1 
ATOM   503  O  OE2 . GLU A 1 75  ? 141.882 151.042 110.341 1.00 85.01  ? 75  GLU A OE2 1 
ATOM   504  N  N   . VAL A 1 76  ? 141.231 152.772 115.084 1.00 79.49  ? 76  VAL A N   1 
ATOM   505  C  CA  . VAL A 1 76  ? 140.551 153.282 116.271 1.00 79.49  ? 76  VAL A CA  1 
ATOM   506  C  C   . VAL A 1 76  ? 139.724 152.203 116.965 1.00 79.49  ? 76  VAL A C   1 
ATOM   507  O  O   . VAL A 1 76  ? 139.887 151.984 118.167 1.00 79.49  ? 76  VAL A O   1 
ATOM   508  C  CB  . VAL A 1 76  ? 139.704 154.526 115.906 1.00 79.49  ? 76  VAL A CB  1 
ATOM   509  C  CG1 . VAL A 1 76  ? 138.811 154.271 114.690 1.00 79.49  ? 76  VAL A CG1 1 
ATOM   510  C  CG2 . VAL A 1 76  ? 138.871 154.975 117.101 1.00 79.49  ? 76  VAL A CG2 1 
ATOM   511  N  N   . VAL A 1 77  ? 138.866 151.488 116.227 1.00 70.24  ? 77  VAL A N   1 
ATOM   512  C  CA  . VAL A 1 77  ? 137.835 150.661 116.854 1.00 70.24  ? 77  VAL A CA  1 
ATOM   513  C  C   . VAL A 1 77  ? 138.449 149.493 117.620 1.00 70.24  ? 77  VAL A C   1 
ATOM   514  O  O   . VAL A 1 77  ? 138.009 149.166 118.731 1.00 70.24  ? 77  VAL A O   1 
ATOM   515  C  CB  . VAL A 1 77  ? 136.813 150.194 115.799 1.00 70.24  ? 77  VAL A CB  1 
ATOM   516  C  CG1 . VAL A 1 77  ? 135.963 151.370 115.344 1.00 70.24  ? 77  VAL A CG1 1 
ATOM   517  C  CG2 . VAL A 1 77  ? 137.515 149.577 114.594 1.00 70.24  ? 77  VAL A CG2 1 
ATOM   518  N  N   . GLU A 1 78  ? 139.481 148.860 117.057 1.00 71.39  ? 78  GLU A N   1 
ATOM   519  C  CA  . GLU A 1 78  ? 140.176 147.798 117.777 1.00 71.39  ? 78  GLU A CA  1 
ATOM   520  C  C   . GLU A 1 78  ? 140.844 148.335 119.036 1.00 71.39  ? 78  GLU A C   1 
ATOM   521  O  O   . GLU A 1 78  ? 140.834 147.675 120.082 1.00 71.39  ? 78  GLU A O   1 
ATOM   522  C  CB  . GLU A 1 78  ? 141.203 147.129 116.863 1.00 71.39  ? 78  GLU A CB  1 
ATOM   523  C  CG  . GLU A 1 78  ? 140.621 146.559 115.579 1.00 71.39  ? 78  GLU A CG  1 
ATOM   524  C  CD  . GLU A 1 78  ? 140.696 147.529 114.419 1.00 71.39  ? 78  GLU A CD  1 
ATOM   525  O  OE1 . GLU A 1 78  ? 140.921 148.731 114.664 1.00 71.39  ? 78  GLU A OE1 1 
ATOM   526  O  OE2 . GLU A 1 78  ? 140.531 147.088 113.262 1.00 71.39  ? 78  GLU A OE2 1 
ATOM   527  N  N   . SER A 1 79  ? 141.428 149.533 118.951 1.00 72.62  ? 79  SER A N   1 
ATOM   528  C  CA  . SER A 1 79  ? 142.062 150.140 120.116 1.00 72.62  ? 79  SER A CA  1 
ATOM   529  C  C   . SER A 1 79  ? 141.049 150.383 121.227 1.00 72.62  ? 79  SER A C   1 
ATOM   530  O  O   . SER A 1 79  ? 141.311 150.076 122.397 1.00 72.62  ? 79  SER A O   1 
ATOM   531  C  CB  . SER A 1 79  ? 142.749 151.447 119.718 1.00 72.62  ? 79  SER A CB  1 
ATOM   532  O  OG  . SER A 1 79  ? 141.796 152.428 119.349 1.00 72.62  ? 79  SER A OG  1 
ATOM   533  N  N   . LEU A 1 80  ? 139.872 150.915 120.875 1.00 74.78  ? 80  LEU A N   1 
ATOM   534  C  CA  . LEU A 1 80  ? 138.828 151.093 121.881 1.00 74.78  ? 80  LEU A CA  1 
ATOM   535  C  C   . LEU A 1 80  ? 138.349 149.762 122.437 1.00 74.78  ? 80  LEU A C   1 
ATOM   536  O  O   . LEU A 1 80  ? 138.044 149.680 123.628 1.00 74.78  ? 80  LEU A O   1 
ATOM   537  C  CB  . LEU A 1 80  ? 137.631 151.876 121.333 1.00 74.78  ? 80  LEU A CB  1 
ATOM   538  C  CG  . LEU A 1 80  ? 137.763 152.937 120.246 1.00 74.78  ? 80  LEU A CG  1 
ATOM   539  C  CD1 . LEU A 1 80  ? 136.389 153.344 119.734 1.00 74.78  ? 80  LEU A CD1 1 
ATOM   540  C  CD2 . LEU A 1 80  ? 138.528 154.142 120.768 1.00 74.78  ? 80  LEU A CD2 1 
ATOM   541  N  N   . ILE A 1 81  ? 138.288 148.713 121.612 1.00 72.17  ? 81  ILE A N   1 
ATOM   542  C  CA  . ILE A 1 81  ? 137.831 147.415 122.109 1.00 72.17  ? 81  ILE A CA  1 
ATOM   543  C  C   . ILE A 1 81  ? 138.798 146.860 123.153 1.00 72.17  ? 81  ILE A C   1 
ATOM   544  O  O   . ILE A 1 81  ? 138.386 146.490 124.261 1.00 72.17  ? 81  ILE A O   1 
ATOM   545  C  CB  . ILE A 1 81  ? 137.626 146.428 120.947 1.00 72.17  ? 81  ILE A CB  1 
ATOM   546  C  CG1 . ILE A 1 81  ? 136.358 146.780 120.168 1.00 72.17  ? 81  ILE A CG1 1 
ATOM   547  C  CG2 . ILE A 1 81  ? 137.536 145.004 121.469 1.00 72.17  ? 81  ILE A CG2 1 
ATOM   548  C  CD1 . ILE A 1 81  ? 135.093 146.731 121.001 1.00 72.17  ? 81  ILE A CD1 1 
ATOM   549  N  N   . ILE A 1 82  ? 140.097 146.816 122.831 1.00 76.14  ? 82  ILE A N   1 
ATOM   550  C  CA  . ILE A 1 82  ? 141.060 146.285 123.800 1.00 76.14  ? 82  ILE A CA  1 
ATOM   551  C  C   . ILE A 1 82  ? 141.128 147.167 125.040 1.00 76.14  ? 82  ILE A C   1 
ATOM   552  O  O   . ILE A 1 82  ? 141.130 146.660 126.171 1.00 76.14  ? 82  ILE A O   1 
ATOM   553  C  CB  . ILE A 1 82  ? 142.458 146.090 123.182 1.00 76.14  ? 82  ILE A CB  1 
ATOM   554  C  CG1 . ILE A 1 82  ? 142.371 145.620 121.735 1.00 76.14  ? 82  ILE A CG1 1 
ATOM   555  C  CG2 . ILE A 1 82  ? 143.269 145.104 124.013 1.00 76.14  ? 82  ILE A CG2 1 
ATOM   556  C  CD1 . ILE A 1 82  ? 143.626 145.880 120.932 1.00 76.14  ? 82  ILE A CD1 1 
ATOM   557  N  N   . PHE A 1 83  ? 141.175 148.494 124.854 1.00 79.19  ? 83  PHE A N   1 
ATOM   558  C  CA  . PHE A 1 83  ? 141.185 149.404 125.994 1.00 79.19  ? 83  PHE A CA  1 
ATOM   559  C  C   . PHE A 1 83  ? 139.945 149.218 126.853 1.00 79.19  ? 83  PHE A C   1 
ATOM   560  O  O   . PHE A 1 83  ? 140.007 149.346 128.082 1.00 79.19  ? 83  PHE A O   1 
ATOM   561  C  CB  . PHE A 1 83  ? 141.286 150.849 125.508 1.00 79.19  ? 83  PHE A CB  1 
ATOM   562  C  CG  . PHE A 1 83  ? 141.844 151.797 126.529 1.00 79.19  ? 83  PHE A CG  1 
ATOM   563  C  CD1 . PHE A 1 83  ? 143.178 151.739 126.896 1.00 79.19  ? 83  PHE A CD1 1 
ATOM   564  C  CD2 . PHE A 1 83  ? 141.032 152.752 127.122 1.00 79.19  ? 83  PHE A CD2 1 
ATOM   565  C  CE1 . PHE A 1 83  ? 143.693 152.613 127.836 1.00 79.19  ? 83  PHE A CE1 1 
ATOM   566  C  CE2 . PHE A 1 83  ? 141.540 153.629 128.062 1.00 79.19  ? 83  PHE A CE2 1 
ATOM   567  C  CZ  . PHE A 1 83  ? 142.873 153.559 128.420 1.00 79.19  ? 83  PHE A CZ  1 
ATOM   568  N  N   . LEU A 1 84  ? 138.818 148.869 126.227 1.00 79.56  ? 84  LEU A N   1 
ATOM   569  C  CA  . LEU A 1 84  ? 137.599 148.635 126.982 1.00 79.56  ? 84  LEU A CA  1 
ATOM   570  C  C   . LEU A 1 84  ? 137.732 147.358 127.799 1.00 79.56  ? 84  LEU A C   1 
ATOM   571  O  O   . LEU A 1 84  ? 137.273 147.303 128.941 1.00 79.56  ? 84  LEU A O   1 
ATOM   572  C  CB  . LEU A 1 84  ? 136.390 148.591 126.038 1.00 79.56  ? 84  LEU A CB  1 
ATOM   573  C  CG  . LEU A 1 84  ? 134.918 148.637 126.511 1.00 79.56  ? 84  LEU A CG  1 
ATOM   574  C  CD1 . LEU A 1 84  ? 134.001 148.745 125.292 1.00 79.56  ? 84  LEU A CD1 1 
ATOM   575  C  CD2 . LEU A 1 84  ? 134.424 147.531 127.448 1.00 79.56  ? 84  LEU A CD2 1 
ATOM   576  N  N   . VAL A 1 85  ? 138.378 146.327 127.235 1.00 76.79  ? 85  VAL A N   1 
ATOM   577  C  CA  . VAL A 1 85  ? 138.643 145.104 128.006 1.00 76.79  ? 85  VAL A CA  1 
ATOM   578  C  C   . VAL A 1 85  ? 139.477 145.415 129.243 1.00 76.79  ? 85  VAL A C   1 
ATOM   579  O  O   . VAL A 1 85  ? 139.167 144.963 130.360 1.00 76.79  ? 85  VAL A O   1 
ATOM   580  C  CB  . VAL A 1 85  ? 139.331 144.030 127.142 1.00 76.79  ? 85  VAL A CB  1 
ATOM   581  C  CG1 . VAL A 1 85  ? 139.346 142.709 127.888 1.00 76.79  ? 85  VAL A CG1 1 
ATOM   582  C  CG2 . VAL A 1 85  ? 138.607 143.829 125.844 1.00 76.79  ? 85  VAL A CG2 1 
ATOM   583  N  N   . LEU A 1 86  ? 140.560 146.182 129.061 1.00 85.57  ? 86  LEU A N   1 
ATOM   584  C  CA  . LEU A 1 86  ? 141.382 146.526 130.221 1.00 85.57  ? 86  LEU A CA  1 
ATOM   585  C  C   . LEU A 1 86  ? 140.601 147.336 131.246 1.00 85.57  ? 86  LEU A C   1 
ATOM   586  O  O   . LEU A 1 86  ? 140.720 147.080 132.450 1.00 85.57  ? 86  LEU A O   1 
ATOM   587  C  CB  . LEU A 1 86  ? 142.683 147.250 129.849 1.00 85.57  ? 86  LEU A CB  1 
ATOM   588  C  CG  . LEU A 1 86  ? 143.817 146.565 129.067 1.00 85.57  ? 86  LEU A CG  1 
ATOM   589  C  CD1 . LEU A 1 86  ? 143.929 145.101 129.495 1.00 85.57  ? 86  LEU A CD1 1 
ATOM   590  C  CD2 . LEU A 1 86  ? 143.836 146.731 127.560 1.00 85.57  ? 86  LEU A CD2 1 
ATOM   591  N  N   . ILE A 1 87  ? 139.772 148.290 130.809 1.00 87.22  ? 87  ILE A N   1 
ATOM   592  C  CA  . ILE A 1 87  ? 139.099 149.080 131.836 1.00 87.22  ? 87  ILE A CA  1 
ATOM   593  C  C   . ILE A 1 87  ? 138.012 148.263 132.531 1.00 87.22  ? 87  ILE A C   1 
ATOM   594  O  O   . ILE A 1 87  ? 137.793 148.451 133.727 1.00 87.22  ? 87  ILE A O   1 
ATOM   595  C  CB  . ILE A 1 87  ? 138.532 150.420 131.322 1.00 87.22  ? 87  ILE A CB  1 
ATOM   596  C  CG1 . ILE A 1 87  ? 137.713 150.255 130.054 1.00 87.22  ? 87  ILE A CG1 1 
ATOM   597  C  CG2 . ILE A 1 87  ? 139.663 151.418 131.096 1.00 87.22  ? 87  ILE A CG2 1 
ATOM   598  C  CD1 . ILE A 1 87  ? 137.225 151.562 129.458 1.00 87.22  ? 87  ILE A CD1 1 
ATOM   599  N  N   . VAL A 1 88  ? 137.328 147.339 131.837 1.00 89.45  ? 88  VAL A N   1 
ATOM   600  C  CA  . VAL A 1 88  ? 136.273 146.602 132.540 1.00 89.45  ? 88  VAL A CA  1 
ATOM   601  C  C   . VAL A 1 88  ? 136.893 145.644 133.550 1.00 89.45  ? 88  VAL A C   1 
ATOM   602  O  O   . VAL A 1 88  ? 136.420 145.543 134.690 1.00 89.45  ? 88  VAL A O   1 
ATOM   603  C  CB  . VAL A 1 88  ? 135.307 145.852 131.591 1.00 89.45  ? 88  VAL A CB  1 
ATOM   604  C  CG1 . VAL A 1 88  ? 136.014 145.048 130.534 1.00 89.45  ? 88  VAL A CG1 1 
ATOM   605  C  CG2 . VAL A 1 88  ? 134.337 144.970 132.374 1.00 89.45  ? 88  VAL A CG2 1 
ATOM   606  N  N   . ASN A 1 89  ? 137.979 144.950 133.173 1.00 88.12  ? 89  ASN A N   1 
ATOM   607  C  CA  . ASN A 1 89  ? 138.586 144.064 134.163 1.00 88.12  ? 89  ASN A CA  1 
ATOM   608  C  C   . ASN A 1 89  ? 139.231 144.854 135.296 1.00 88.12  ? 89  ASN A C   1 
ATOM   609  O  O   . ASN A 1 89  ? 139.164 144.428 136.455 1.00 88.12  ? 89  ASN A O   1 
ATOM   610  C  CB  . ASN A 1 89  ? 139.586 143.097 133.516 1.00 88.12  ? 89  ASN A CB  1 
ATOM   611  C  CG  . ASN A 1 89  ? 140.718 143.795 132.796 1.00 88.12  ? 89  ASN A CG  1 
ATOM   612  O  OD1 . ASN A 1 89  ? 141.530 144.496 133.402 1.00 88.12  ? 89  ASN A OD1 1 
ATOM   613  N  ND2 . ASN A 1 89  ? 140.805 143.566 131.494 1.00 88.12  ? 89  ASN A ND2 1 
ATOM   614  N  N   . SER A 1 90  ? 139.795 146.032 135.001 1.00 98.16  ? 90  SER A N   1 
ATOM   615  C  CA  . SER A 1 90  ? 140.356 146.867 136.056 1.00 98.16  ? 90  SER A CA  1 
ATOM   616  C  C   . SER A 1 90  ? 139.279 147.364 137.015 1.00 98.16  ? 90  SER A C   1 
ATOM   617  O  O   . SER A 1 90  ? 139.465 147.320 138.237 1.00 98.16  ? 90  SER A O   1 
ATOM   618  C  CB  . SER A 1 90  ? 141.111 148.047 135.444 1.00 98.16  ? 90  SER A CB  1 
ATOM   619  O  OG  . SER A 1 90  ? 140.236 149.128 135.173 1.00 98.16  ? 90  SER A OG  1 
ATOM   620  N  N   . ILE A 1 91  ? 138.144 147.839 136.488 1.00 95.91  ? 91  ILE A N   1 
ATOM   621  C  CA  . ILE A 1 91  ? 137.115 148.382 137.368 1.00 95.91  ? 91  ILE A CA  1 
ATOM   622  C  C   . ILE A 1 91  ? 136.442 147.270 138.159 1.00 95.91  ? 91  ILE A C   1 
ATOM   623  O  O   . ILE A 1 91  ? 136.096 147.465 139.325 1.00 95.91  ? 91  ILE A O   1 
ATOM   624  C  CB  . ILE A 1 91  ? 136.088 149.247 136.603 1.00 95.91  ? 91  ILE A CB  1 
ATOM   625  C  CG1 . ILE A 1 91  ? 135.273 148.433 135.592 1.00 95.91  ? 91  ILE A CG1 1 
ATOM   626  C  CG2 . ILE A 1 91  ? 136.762 150.466 135.975 1.00 95.91  ? 91  ILE A CG2 1 
ATOM   627  C  CD1 . ILE A 1 91  ? 133.812 148.286 135.962 1.00 95.91  ? 91  ILE A CD1 1 
ATOM   628  N  N   . ILE A 1 92  ? 136.255 146.087 137.564 1.00 89.71  ? 92  ILE A N   1 
ATOM   629  C  CA  . ILE A 1 92  ? 135.658 145.009 138.349 1.00 89.71  ? 92  ILE A CA  1 
ATOM   630  C  C   . ILE A 1 92  ? 136.635 144.526 139.419 1.00 89.71  ? 92  ILE A C   1 
ATOM   631  O  O   . ILE A 1 92  ? 136.222 144.224 140.550 1.00 89.71  ? 92  ILE A O   1 
ATOM   632  C  CB  . ILE A 1 92  ? 135.145 143.870 137.439 1.00 89.71  ? 92  ILE A CB  1 
ATOM   633  C  CG1 . ILE A 1 92  ? 134.169 142.975 138.207 1.00 89.71  ? 92  ILE A CG1 1 
ATOM   634  C  CG2 . ILE A 1 92  ? 136.269 143.034 136.847 1.00 89.71  ? 92  ILE A CG2 1 
ATOM   635  C  CD1 . ILE A 1 92  ? 132.964 142.553 137.397 1.00 89.71  ? 92  ILE A CD1 1 
ATOM   636  N  N   . SER A 1 93  ? 137.940 144.511 139.115 1.00 99.86  ? 93  SER A N   1 
ATOM   637  C  CA  . SER A 1 93  ? 138.933 144.134 140.114 1.00 99.86  ? 93  SER A CA  1 
ATOM   638  C  C   . SER A 1 93  ? 138.957 145.129 141.266 1.00 99.86  ? 93  SER A C   1 
ATOM   639  O  O   . SER A 1 93  ? 138.955 144.734 142.435 1.00 99.86  ? 93  SER A O   1 
ATOM   640  C  CB  . SER A 1 93  ? 140.313 144.026 139.465 1.00 99.86  ? 93  SER A CB  1 
ATOM   641  O  OG  . SER A 1 93  ? 140.774 145.294 139.033 1.00 99.86  ? 93  SER A OG  1 
ATOM   642  N  N   . VAL A 1 94  ? 138.941 146.428 140.959 1.00 103.25 ? 94  VAL A N   1 
ATOM   643  C  CA  . VAL A 1 94  ? 139.016 147.411 142.037 1.00 103.25 ? 94  VAL A CA  1 
ATOM   644  C  C   . VAL A 1 94  ? 137.679 147.547 142.764 1.00 103.25 ? 94  VAL A C   1 
ATOM   645  O  O   . VAL A 1 94  ? 137.656 147.893 143.947 1.00 103.25 ? 94  VAL A O   1 
ATOM   646  C  CB  . VAL A 1 94  ? 139.518 148.773 141.522 1.00 103.25 ? 94  VAL A CB  1 
ATOM   647  C  CG1 . VAL A 1 94  ? 140.883 148.625 140.862 1.00 103.25 ? 94  VAL A CG1 1 
ATOM   648  C  CG2 . VAL A 1 94  ? 138.515 149.413 140.580 1.00 103.25 ? 94  VAL A CG2 1 
ATOM   649  N  N   . VAL A 1 95  ? 136.555 147.249 142.107 1.00 105.06 ? 95  VAL A N   1 
ATOM   650  C  CA  . VAL A 1 95  ? 135.267 147.277 142.791 1.00 105.06 ? 95  VAL A CA  1 
ATOM   651  C  C   . VAL A 1 95  ? 135.164 146.123 143.778 1.00 105.06 ? 95  VAL A C   1 
ATOM   652  O  O   . VAL A 1 95  ? 134.740 146.308 144.926 1.00 105.06 ? 95  VAL A O   1 
ATOM   653  C  CB  . VAL A 1 95  ? 134.115 147.270 141.767 1.00 105.06 ? 95  VAL A CB  1 
ATOM   654  C  CG1 . VAL A 1 95  ? 132.840 146.705 142.379 1.00 105.06 ? 95  VAL A CG1 1 
ATOM   655  C  CG2 . VAL A 1 95  ? 133.856 148.683 141.264 1.00 105.06 ? 95  VAL A CG2 1 
ATOM   656  N  N   . GLN A 1 96  ? 135.573 144.919 143.369 1.00 100.38 ? 96  GLN A N   1 
ATOM   657  C  CA  . GLN A 1 96  ? 135.579 143.828 144.334 1.00 100.38 ? 96  GLN A CA  1 
ATOM   658  C  C   . GLN A 1 96  ? 136.695 143.976 145.362 1.00 100.38 ? 96  GLN A C   1 
ATOM   659  O  O   . GLN A 1 96  ? 136.556 143.473 146.479 1.00 100.38 ? 96  GLN A O   1 
ATOM   660  C  CB  . GLN A 1 96  ? 135.669 142.484 143.615 1.00 100.38 ? 96  GLN A CB  1 
ATOM   661  C  CG  . GLN A 1 96  ? 134.307 141.951 143.188 1.00 100.38 ? 96  GLN A CG  1 
ATOM   662  C  CD  . GLN A 1 96  ? 133.444 141.523 144.360 1.00 100.38 ? 96  GLN A CD  1 
ATOM   663  O  OE1 . GLN A 1 96  ? 133.950 141.196 145.434 1.00 100.38 ? 96  GLN A OE1 1 
ATOM   664  N  NE2 . GLN A 1 96  ? 132.132 141.518 144.156 1.00 100.38 ? 96  GLN A NE2 1 
ATOM   665  N  N   . THR A 1 97  ? 137.772 144.694 145.033 1.00 112.49 ? 97  THR A N   1 
ATOM   666  C  CA  . THR A 1 97  ? 138.770 145.031 146.043 1.00 112.49 ? 97  THR A CA  1 
ATOM   667  C  C   . THR A 1 97  ? 138.208 146.008 147.069 1.00 112.49 ? 97  THR A C   1 
ATOM   668  O  O   . THR A 1 97  ? 138.504 145.899 148.261 1.00 112.49 ? 97  THR A O   1 
ATOM   669  C  CB  . THR A 1 97  ? 140.019 145.611 145.378 1.00 112.49 ? 97  THR A CB  1 
ATOM   670  O  OG1 . THR A 1 97  ? 140.356 144.829 144.226 1.00 112.49 ? 97  THR A OG1 1 
ATOM   671  C  CG2 . THR A 1 97  ? 141.193 145.603 146.347 1.00 112.49 ? 97  THR A CG2 1 
ATOM   672  N  N   . ARG A 1 98  ? 137.397 146.971 146.623 1.00 116.57 ? 98  ARG A N   1 
ATOM   673  C  CA  . ARG A 1 98  ? 136.722 147.874 147.551 1.00 116.57 ? 98  ARG A CA  1 
ATOM   674  C  C   . ARG A 1 98  ? 135.703 147.126 148.400 1.00 116.57 ? 98  ARG A C   1 
ATOM   675  O  O   . ARG A 1 98  ? 135.530 147.430 149.586 1.00 116.57 ? 98  ARG A O   1 
ATOM   676  C  CB  . ARG A 1 98  ? 136.051 149.008 146.777 1.00 116.57 ? 98  ARG A CB  1 
ATOM   677  C  CG  . ARG A 1 98  ? 135.485 150.116 147.651 1.00 116.57 ? 98  ARG A CG  1 
ATOM   678  C  CD  . ARG A 1 98  ? 134.758 151.157 146.815 1.00 116.57 ? 98  ARG A CD  1 
ATOM   679  N  NE  . ARG A 1 98  ? 134.045 152.123 147.642 1.00 116.57 ? 98  ARG A NE  1 
ATOM   680  C  CZ  . ARG A 1 98  ? 134.447 153.369 147.855 1.00 116.57 ? 98  ARG A CZ  1 
ATOM   681  N  NH1 . ARG A 1 98  ? 135.556 153.840 147.309 1.00 116.57 ? 98  ARG A NH1 1 
ATOM   682  N  NH2 . ARG A 1 98  ? 133.717 154.162 148.634 1.00 116.57 ? 98  ARG A NH2 1 
ATOM   683  N  N   . LYS A 1 99  ? 135.015 146.149 147.804 1.00 113.11 ? 99  LYS A N   1 
ATOM   684  C  CA  . LYS A 1 99  ? 134.117 145.292 148.574 1.00 113.11 ? 99  LYS A CA  1 
ATOM   685  C  C   . LYS A 1 99  ? 134.884 144.498 149.624 1.00 113.11 ? 99  LYS A C   1 
ATOM   686  O  O   . LYS A 1 99  ? 134.430 144.360 150.765 1.00 113.11 ? 99  LYS A O   1 
ATOM   687  C  CB  . LYS A 1 99  ? 133.359 144.351 147.637 1.00 113.11 ? 99  LYS A CB  1 
ATOM   688  C  CG  . LYS A 1 99  ? 132.434 143.374 148.346 1.00 113.11 ? 99  LYS A CG  1 
ATOM   689  C  CD  . LYS A 1 99  ? 131.606 142.575 147.353 1.00 113.11 ? 99  LYS A CD  1 
ATOM   690  C  CE  . LYS A 1 99  ? 130.652 141.626 148.060 1.00 113.11 ? 99  LYS A CE  1 
ATOM   691  N  NZ  . LYS A 1 99  ? 129.857 140.818 147.095 1.00 113.11 ? 99  LYS A NZ  1 
ATOM   692  N  N   . ALA A 1 100 ? 136.059 143.979 149.256 1.00 128.45 ? 100 ALA A N   1 
ATOM   693  C  CA  . ALA A 1 100 ? 136.904 143.272 150.212 1.00 128.45 ? 100 ALA A CA  1 
ATOM   694  C  C   . ALA A 1 100 ? 137.408 144.203 151.308 1.00 128.45 ? 100 ALA A C   1 
ATOM   695  O  O   . ALA A 1 100 ? 137.512 143.798 152.468 1.00 128.45 ? 100 ALA A O   1 
ATOM   696  C  CB  . ALA A 1 100 ? 138.077 142.613 149.487 1.00 128.45 ? 100 ALA A CB  1 
ATOM   697  N  N   . GLU A 1 101 ? 137.739 145.448 150.956 1.00 131.78 ? 101 GLU A N   1 
ATOM   698  C  CA  . GLU A 1 101 ? 138.170 146.423 151.954 1.00 131.78 ? 101 GLU A CA  1 
ATOM   699  C  C   . GLU A 1 101 ? 137.047 146.753 152.929 1.00 131.78 ? 101 GLU A C   1 
ATOM   700  O  O   . GLU A 1 101 ? 137.277 146.847 154.139 1.00 131.78 ? 101 GLU A O   1 
ATOM   701  C  CB  . GLU A 1 101 ? 138.667 147.697 151.269 1.00 131.78 ? 101 GLU A CB  1 
ATOM   702  C  CG  . GLU A 1 101 ? 140.019 147.564 150.590 1.00 131.78 ? 101 GLU A CG  1 
ATOM   703  C  CD  . GLU A 1 101 ? 140.125 148.418 149.340 1.00 131.78 ? 101 GLU A CD  1 
ATOM   704  O  OE1 . GLU A 1 101 ? 139.290 149.331 149.170 1.00 131.78 ? 101 GLU A OE1 1 
ATOM   705  O  OE2 . GLU A 1 101 ? 141.041 148.175 148.527 1.00 131.78 ? 101 GLU A OE2 1 
ATOM   706  N  N   . SER A 1 102 ? 135.827 146.936 152.417 1.00 141.85 ? 102 SER A N   1 
ATOM   707  C  CA  . SER A 1 102 ? 134.682 147.185 153.289 1.00 141.85 ? 102 SER A CA  1 
ATOM   708  C  C   . SER A 1 102 ? 134.398 145.981 154.178 1.00 141.85 ? 102 SER A C   1 
ATOM   709  O  O   . SER A 1 102 ? 134.085 146.133 155.365 1.00 141.85 ? 102 SER A O   1 
ATOM   710  C  CB  . SER A 1 102 ? 133.452 147.538 152.453 1.00 141.85 ? 102 SER A CB  1 
ATOM   711  O  OG  . SER A 1 102 ? 132.909 146.385 151.833 1.00 141.85 ? 102 SER A OG  1 
ATOM   712  N  N   . SER A 1 103 ? 134.511 144.773 153.619 1.00 144.21 ? 103 SER A N   1 
ATOM   713  C  CA  . SER A 1 103 ? 134.333 143.563 154.413 1.00 144.21 ? 103 SER A CA  1 
ATOM   714  C  C   . SER A 1 103 ? 135.393 143.454 155.501 1.00 144.21 ? 103 SER A C   1 
ATOM   715  O  O   . SER A 1 103 ? 135.081 143.100 156.640 1.00 144.21 ? 103 SER A O   1 
ATOM   716  C  CB  . SER A 1 103 ? 134.364 142.333 153.507 1.00 144.21 ? 103 SER A CB  1 
ATOM   717  O  OG  . SER A 1 103 ? 135.692 142.006 153.139 1.00 144.21 ? 103 SER A OG  1 
ATOM   718  N  N   . LEU A 1 104 ? 136.650 143.762 155.169 1.00 147.66 ? 104 LEU A N   1 
ATOM   719  C  CA  . LEU A 1 104 ? 137.729 143.710 156.151 1.00 147.66 ? 104 LEU A CA  1 
ATOM   720  C  C   . LEU A 1 104 ? 137.537 144.755 157.241 1.00 147.66 ? 104 LEU A C   1 
ATOM   721  O  O   . LEU A 1 104 ? 137.834 144.499 158.414 1.00 147.66 ? 104 LEU A O   1 
ATOM   722  C  CB  . LEU A 1 104 ? 139.077 143.901 155.457 1.00 147.66 ? 104 LEU A CB  1 
ATOM   723  C  CG  . LEU A 1 104 ? 139.959 142.660 155.304 1.00 147.66 ? 104 LEU A CG  1 
ATOM   724  C  CD1 . LEU A 1 104 ? 140.445 142.177 156.661 1.00 147.66 ? 104 LEU A CD1 1 
ATOM   725  C  CD2 . LEU A 1 104 ? 139.215 141.555 154.570 1.00 147.66 ? 104 LEU A CD2 1 
ATOM   726  N  N   . ASP A 1 105 ? 137.051 145.943 156.871 1.00 156.27 ? 105 ASP A N   1 
ATOM   727  C  CA  . ASP A 1 105 ? 136.717 146.952 157.870 1.00 156.27 ? 105 ASP A CA  1 
ATOM   728  C  C   . ASP A 1 105 ? 135.597 146.467 158.781 1.00 156.27 ? 105 ASP A C   1 
ATOM   729  O  O   . ASP A 1 105 ? 135.633 146.693 159.995 1.00 156.27 ? 105 ASP A O   1 
ATOM   730  C  CB  . ASP A 1 105 ? 136.325 148.262 157.186 1.00 156.27 ? 105 ASP A CB  1 
ATOM   731  C  CG  . ASP A 1 105 ? 137.489 148.916 156.470 1.00 156.27 ? 105 ASP A CG  1 
ATOM   732  O  OD1 . ASP A 1 105 ? 138.632 148.795 156.957 1.00 156.27 ? 105 ASP A OD1 1 
ATOM   733  O  OD2 . ASP A 1 105 ? 137.261 149.551 155.419 1.00 156.27 ? 105 ASP A OD2 1 
ATOM   734  N  N   . ALA A 1 106 ? 134.601 145.782 158.214 1.00 156.03 ? 106 ALA A N   1 
ATOM   735  C  CA  . ALA A 1 106 ? 133.539 145.204 159.033 1.00 156.03 ? 106 ALA A CA  1 
ATOM   736  C  C   . ALA A 1 106 ? 134.085 144.148 159.989 1.00 156.03 ? 106 ALA A C   1 
ATOM   737  O  O   . ALA A 1 106 ? 133.698 144.108 161.163 1.00 156.03 ? 106 ALA A O   1 
ATOM   738  C  CB  . ALA A 1 106 ? 132.452 144.609 158.138 1.00 156.03 ? 106 ALA A CB  1 
ATOM   739  N  N   . LEU A 1 107 ? 134.984 143.285 159.501 1.00 149.67 ? 107 LEU A N   1 
ATOM   740  C  CA  . LEU A 1 107 ? 135.582 142.259 160.356 1.00 149.67 ? 107 LEU A CA  1 
ATOM   741  C  C   . LEU A 1 107 ? 136.398 142.884 161.479 1.00 149.67 ? 107 LEU A C   1 
ATOM   742  O  O   . LEU A 1 107 ? 136.343 142.425 162.626 1.00 149.67 ? 107 LEU A O   1 
ATOM   743  C  CB  . LEU A 1 107 ? 136.460 141.309 159.536 1.00 149.67 ? 107 LEU A CB  1 
ATOM   744  C  CG  . LEU A 1 107 ? 135.881 140.599 158.310 1.00 149.67 ? 107 LEU A CG  1 
ATOM   745  C  CD1 . LEU A 1 107 ? 136.816 139.509 157.801 1.00 149.67 ? 107 LEU A CD1 1 
ATOM   746  C  CD2 . LEU A 1 107 ? 134.497 140.043 158.600 1.00 149.67 ? 107 LEU A CD2 1 
ATOM   747  N  N   . ARG A 1 108 ? 137.161 143.933 161.170 1.00 159.32 ? 108 ARG A N   1 
ATOM   748  C  CA  . ARG A 1 108 ? 137.886 144.659 162.204 1.00 159.32 ? 108 ARG A CA  1 
ATOM   749  C  C   . ARG A 1 108 ? 136.949 145.413 163.138 1.00 159.32 ? 108 ARG A C   1 
ATOM   750  O  O   . ARG A 1 108 ? 137.347 145.745 164.258 1.00 159.32 ? 108 ARG A O   1 
ATOM   751  C  CB  . ARG A 1 108 ? 138.880 145.631 161.568 1.00 159.32 ? 108 ARG A CB  1 
ATOM   752  C  CG  . ARG A 1 108 ? 140.318 145.135 161.553 1.00 159.32 ? 108 ARG A CG  1 
ATOM   753  C  CD  . ARG A 1 108 ? 140.688 144.552 160.199 1.00 159.32 ? 108 ARG A CD  1 
ATOM   754  N  NE  . ARG A 1 108 ? 140.144 145.338 159.098 1.00 159.32 ? 108 ARG A NE  1 
ATOM   755  C  CZ  . ARG A 1 108 ? 140.809 146.287 158.453 1.00 159.32 ? 108 ARG A CZ  1 
ATOM   756  N  NH1 . ARG A 1 108 ? 142.055 146.596 158.773 1.00 159.32 ? 108 ARG A NH1 1 
ATOM   757  N  NH2 . ARG A 1 108 ? 140.210 146.941 157.463 1.00 159.32 ? 108 ARG A NH2 1 
ATOM   758  N  N   . GLU A 1 109 ? 135.722 145.698 162.698 1.00 167.60 ? 109 GLU A N   1 
ATOM   759  C  CA  . GLU A 1 109 ? 134.776 146.429 163.534 1.00 167.60 ? 109 GLU A CA  1 
ATOM   760  C  C   . GLU A 1 109 ? 134.084 145.512 164.539 1.00 167.60 ? 109 GLU A C   1 
ATOM   761  O  O   . GLU A 1 109 ? 134.142 145.752 165.750 1.00 167.60 ? 109 GLU A O   1 
ATOM   762  C  CB  . GLU A 1 109 ? 133.745 147.142 162.653 1.00 167.60 ? 109 GLU A CB  1 
ATOM   763  C  CG  . GLU A 1 109 ? 132.509 147.617 163.399 1.00 167.60 ? 109 GLU A CG  1 
ATOM   764  C  CD  . GLU A 1 109 ? 132.836 148.634 164.475 1.00 167.60 ? 109 GLU A CD  1 
ATOM   765  O  OE1 . GLU A 1 109 ? 133.582 149.592 164.183 1.00 167.60 ? 109 GLU A OE1 1 
ATOM   766  O  OE2 . GLU A 1 109 ? 132.349 148.473 165.614 1.00 167.60 ? 109 GLU A OE2 1 
ATOM   767  N  N   . MET A 1 110 ? 133.413 144.457 164.060 1.00 166.64 ? 110 MET A N   1 
ATOM   768  C  CA  . MET A 1 110 ? 132.644 143.628 164.987 1.00 166.64 ? 110 MET A CA  1 
ATOM   769  C  C   . MET A 1 110 ? 133.534 142.728 165.838 1.00 166.64 ? 110 MET A C   1 
ATOM   770  O  O   . MET A 1 110 ? 133.211 142.474 167.003 1.00 166.64 ? 110 MET A O   1 
ATOM   771  C  CB  . MET A 1 110 ? 131.591 142.790 164.247 1.00 166.64 ? 110 MET A CB  1 
ATOM   772  C  CG  . MET A 1 110 ? 131.999 142.169 162.918 1.00 166.64 ? 110 MET A CG  1 
ATOM   773  S  SD  . MET A 1 110 ? 133.375 141.007 162.974 1.00 166.64 ? 110 MET A SD  1 
ATOM   774  C  CE  . MET A 1 110 ? 132.622 139.642 163.852 1.00 166.64 ? 110 MET A CE  1 
ATOM   775  N  N   . SER A 1 111 ? 134.647 142.242 165.287 1.00 169.80 ? 111 SER A N   1 
ATOM   776  C  CA  . SER A 1 111 ? 135.610 141.452 166.044 1.00 169.80 ? 111 SER A CA  1 
ATOM   777  C  C   . SER A 1 111 ? 136.765 142.303 166.558 1.00 169.80 ? 111 SER A C   1 
ATOM   778  O  O   . SER A 1 111 ? 137.898 141.819 166.662 1.00 169.80 ? 111 SER A O   1 
ATOM   779  C  CB  . SER A 1 111 ? 136.138 140.290 165.201 1.00 169.80 ? 111 SER A CB  1 
ATOM   780  O  OG  . SER A 1 111 ? 136.813 140.755 164.047 1.00 169.80 ? 111 SER A OG  1 
ATOM   781  N  N   . ALA A 1 112 ? 136.498 143.570 166.868 1.00 164.41 ? 112 ALA A N   1 
ATOM   782  C  CA  . ALA A 1 112 ? 137.521 144.448 167.404 1.00 164.41 ? 112 ALA A CA  1 
ATOM   783  C  C   . ALA A 1 112 ? 137.939 143.987 168.799 1.00 164.41 ? 112 ALA A C   1 
ATOM   784  O  O   . ALA A 1 112 ? 137.127 143.437 169.549 1.00 164.41 ? 112 ALA A O   1 
ATOM   785  C  CB  . ALA A 1 112 ? 137.013 145.885 167.470 1.00 164.41 ? 112 ALA A CB  1 
ATOM   786  N  N   . PRO A 1 113 ? 139.210 144.183 169.165 1.00 151.67 ? 113 PRO A N   1 
ATOM   787  C  CA  . PRO A 1 113 ? 139.633 143.866 170.535 1.00 151.67 ? 113 PRO A CA  1 
ATOM   788  C  C   . PRO A 1 113 ? 138.951 144.765 171.551 1.00 151.67 ? 113 PRO A C   1 
ATOM   789  O  O   . PRO A 1 113 ? 139.213 145.970 171.608 1.00 151.67 ? 113 PRO A O   1 
ATOM   790  C  CB  . PRO A 1 113 ? 141.149 144.098 170.503 1.00 151.67 ? 113 PRO A CB  1 
ATOM   791  C  CG  . PRO A 1 113 ? 141.387 144.974 169.317 1.00 151.67 ? 113 PRO A CG  1 
ATOM   792  C  CD  . PRO A 1 113 ? 140.335 144.617 168.319 1.00 151.67 ? 113 PRO A CD  1 
ATOM   793  N  N   . VAL A 1 114 ? 138.071 144.184 172.359 1.00 155.96 ? 114 VAL A N   1 
ATOM   794  C  CA  . VAL A 1 114 ? 137.279 144.930 173.327 1.00 155.96 ? 114 VAL A CA  1 
ATOM   795  C  C   . VAL A 1 114 ? 137.972 144.832 174.677 1.00 155.96 ? 114 VAL A C   1 
ATOM   796  O  O   . VAL A 1 114 ? 138.167 143.732 175.208 1.00 155.96 ? 114 VAL A O   1 
ATOM   797  C  CB  . VAL A 1 114 ? 135.839 144.398 173.399 1.00 155.96 ? 114 VAL A CB  1 
ATOM   798  C  CG1 . VAL A 1 114 ? 135.117 144.984 174.596 1.00 155.96 ? 114 VAL A CG1 1 
ATOM   799  C  CG2 . VAL A 1 114 ? 135.093 144.714 172.111 1.00 155.96 ? 114 VAL A CG2 1 
ATOM   800  N  N   . ALA A 1 115 ? 138.345 145.980 175.233 1.00 160.09 ? 115 ALA A N   1 
ATOM   801  C  CA  . ALA A 1 115 ? 139.038 146.045 176.512 1.00 160.09 ? 115 ALA A CA  1 
ATOM   802  C  C   . ALA A 1 115 ? 138.031 146.377 177.605 1.00 160.09 ? 115 ALA A C   1 
ATOM   803  O  O   . ALA A 1 115 ? 137.334 147.395 177.524 1.00 160.09 ? 115 ALA A O   1 
ATOM   804  C  CB  . ALA A 1 115 ? 140.157 147.085 176.476 1.00 160.09 ? 115 ALA A CB  1 
ATOM   805  N  N   . LYS A 1 116 ? 137.952 145.514 178.617 1.00 157.68 ? 116 LYS A N   1 
ATOM   806  C  CA  . LYS A 1 116 ? 137.067 145.746 179.751 1.00 157.68 ? 116 LYS A CA  1 
ATOM   807  C  C   . LYS A 1 116 ? 137.577 146.939 180.548 1.00 157.68 ? 116 LYS A C   1 
ATOM   808  O  O   . LYS A 1 116 ? 138.667 146.887 181.126 1.00 157.68 ? 116 LYS A O   1 
ATOM   809  C  CB  . LYS A 1 116 ? 136.959 144.504 180.648 1.00 157.68 ? 116 LYS A CB  1 
ATOM   810  C  CG  . LYS A 1 116 ? 136.878 143.154 179.928 1.00 157.68 ? 116 LYS A CG  1 
ATOM   811  C  CD  . LYS A 1 116 ? 138.253 142.527 179.694 1.00 157.68 ? 116 LYS A CD  1 
ATOM   812  C  CE  . LYS A 1 116 ? 138.186 141.397 178.679 1.00 157.68 ? 116 LYS A CE  1 
ATOM   813  N  NZ  . LYS A 1 116 ? 137.959 141.899 177.296 1.00 157.68 ? 116 LYS A NZ  1 
ATOM   814  N  N   . VAL A 1 117 ? 136.802 148.018 180.581 1.00 161.56 ? 117 VAL A N   1 
ATOM   815  C  CA  . VAL A 1 117 ? 137.238 149.279 181.168 1.00 161.56 ? 117 VAL A CA  1 
ATOM   816  C  C   . VAL A 1 117 ? 136.523 149.467 182.503 1.00 161.56 ? 117 VAL A C   1 
ATOM   817  O  O   . VAL A 1 117 ? 135.294 149.365 182.592 1.00 161.56 ? 117 VAL A O   1 
ATOM   818  C  CB  . VAL A 1 117 ? 136.994 150.459 180.215 1.00 161.56 ? 117 VAL A CB  1 
ATOM   819  C  CG1 . VAL A 1 117 ? 137.977 150.411 179.064 1.00 161.56 ? 117 VAL A CG1 1 
ATOM   820  C  CG2 . VAL A 1 117 ? 135.576 150.438 179.660 1.00 161.56 ? 117 VAL A CG2 1 
ATOM   821  N  N   . ILE A 1 118 ? 137.304 149.709 183.558 1.00 163.68 ? 118 ILE A N   1 
ATOM   822  C  CA  . ILE A 1 118 ? 136.741 150.043 184.861 1.00 163.68 ? 118 ILE A CA  1 
ATOM   823  C  C   . ILE A 1 118 ? 136.355 151.514 184.944 1.00 163.68 ? 118 ILE A C   1 
ATOM   824  O  O   . ILE A 1 118 ? 135.381 151.854 185.630 1.00 163.68 ? 118 ILE A O   1 
ATOM   825  C  CB  . ILE A 1 118 ? 137.748 149.609 185.951 1.00 163.68 ? 118 ILE A CB  1 
ATOM   826  C  CG1 . ILE A 1 118 ? 137.578 148.117 186.257 1.00 163.68 ? 118 ILE A CG1 1 
ATOM   827  C  CG2 . ILE A 1 118 ? 137.618 150.432 187.228 1.00 163.68 ? 118 ILE A CG2 1 
ATOM   828  C  CD1 . ILE A 1 118 ? 136.350 147.789 187.086 1.00 163.68 ? 118 ILE A CD1 1 
ATOM   829  N  N   . ARG A 1 119 ? 137.101 152.347 184.206 1.00 156.30 ? 119 ARG A N   1 
ATOM   830  C  CA  . ARG A 1 119 ? 136.825 153.807 184.154 1.00 156.30 ? 119 ARG A CA  1 
ATOM   831  C  C   . ARG A 1 119 ? 136.752 154.380 185.569 1.00 156.30 ? 119 ARG A C   1 
ATOM   832  O  O   . ARG A 1 119 ? 137.585 153.999 186.414 1.00 156.30 ? 119 ARG A O   1 
ATOM   833  C  CB  . ARG A 1 119 ? 135.521 154.090 183.402 1.00 156.30 ? 119 ARG A CB  1 
ATOM   834  C  CG  . ARG A 1 119 ? 135.334 153.260 182.141 1.00 156.30 ? 119 ARG A CG  1 
ATOM   835  C  CD  . ARG A 1 119 ? 135.997 153.927 180.955 1.00 156.30 ? 119 ARG A CD  1 
ATOM   836  N  NE  . ARG A 1 119 ? 135.014 154.452 180.021 1.00 156.30 ? 119 ARG A NE  1 
ATOM   837  C  CZ  . ARG A 1 119 ? 135.317 155.042 178.872 1.00 156.30 ? 119 ARG A CZ  1 
ATOM   838  N  NH1 . ARG A 1 119 ? 136.559 155.426 178.637 1.00 156.30 ? 119 ARG A NH1 1 
ATOM   839  N  NH2 . ARG A 1 119 ? 134.380 155.241 177.961 1.00 156.30 ? 119 ARG A NH2 1 
ATOM   840  N  N   . ASP A 1 120 ? 135.795 155.276 185.796 1.00 159.25 ? 120 ASP A N   1 
ATOM   841  C  CA  . ASP A 1 120 ? 135.642 155.899 187.104 1.00 159.25 ? 120 ASP A CA  1 
ATOM   842  C  C   . ASP A 1 120 ? 134.803 155.013 188.013 1.00 159.25 ? 120 ASP A C   1 
ATOM   843  O  O   . ASP A 1 120 ? 133.827 155.476 188.610 1.00 159.25 ? 120 ASP A O   1 
ATOM   844  C  CB  . ASP A 1 120 ? 134.999 157.279 186.960 1.00 159.25 ? 120 ASP A CB  1 
ATOM   845  C  CG  . ASP A 1 120 ? 135.495 158.027 185.729 1.00 159.25 ? 120 ASP A CG  1 
ATOM   846  O  OD1 . ASP A 1 120 ? 136.698 158.374 185.689 1.00 159.25 ? 120 ASP A OD1 1 
ATOM   847  O  OD2 . ASP A 1 120 ? 134.687 158.254 184.801 1.00 159.25 ? 120 ASP A OD2 1 
ATOM   848  N  N   . GLY A 1 121 ? 135.185 153.741 188.131 1.00 164.66 ? 121 GLY A N   1 
ATOM   849  C  CA  . GLY A 1 121 ? 134.402 152.761 188.843 1.00 164.66 ? 121 GLY A CA  1 
ATOM   850  C  C   . GLY A 1 121 ? 133.278 152.152 188.034 1.00 164.66 ? 121 GLY A C   1 
ATOM   851  O  O   . GLY A 1 121 ? 132.627 151.216 188.510 1.00 164.66 ? 121 GLY A O   1 
ATOM   852  N  N   . SER A 1 122 ? 133.044 152.645 186.816 1.00 170.91 ? 122 SER A N   1 
ATOM   853  C  CA  . SER A 1 122 ? 131.942 152.189 185.969 1.00 170.91 ? 122 SER A CA  1 
ATOM   854  C  C   . SER A 1 122 ? 132.426 151.028 185.106 1.00 170.91 ? 122 SER A C   1 
ATOM   855  O  O   . SER A 1 122 ? 133.087 151.199 184.080 1.00 170.91 ? 122 SER A O   1 
ATOM   856  C  CB  . SER A 1 122 ? 131.420 153.338 185.116 1.00 170.91 ? 122 SER A CB  1 
ATOM   857  O  OG  . SER A 1 122 ? 130.694 152.853 184.000 1.00 170.91 ? 122 SER A OG  1 
ATOM   858  N  N   . LYS A 1 123 ? 132.082 149.816 185.540 1.00 173.94 ? 123 LYS A N   1 
ATOM   859  C  CA  . LYS A 1 123 ? 132.537 148.604 184.871 1.00 173.94 ? 123 LYS A CA  1 
ATOM   860  C  C   . LYS A 1 123 ? 131.791 148.407 183.555 1.00 173.94 ? 123 LYS A C   1 
ATOM   861  O  O   . LYS A 1 123 ? 130.612 148.038 183.547 1.00 173.94 ? 123 LYS A O   1 
ATOM   862  C  CB  . LYS A 1 123 ? 132.351 147.395 185.795 1.00 173.94 ? 123 LYS A CB  1 
ATOM   863  C  CG  . LYS A 1 123 ? 132.581 146.028 185.152 1.00 173.94 ? 123 LYS A CG  1 
ATOM   864  C  CD  . LYS A 1 123 ? 133.967 145.917 184.530 1.00 173.94 ? 123 LYS A CD  1 
ATOM   865  C  CE  . LYS A 1 123 ? 133.984 144.899 183.402 1.00 173.94 ? 123 LYS A CE  1 
ATOM   866  N  NZ  . LYS A 1 123 ? 133.410 145.445 182.144 1.00 173.94 ? 123 LYS A NZ  1 
ATOM   867  N  N   . GLN A 1 124 ? 132.467 148.664 182.441 1.00 172.84 ? 124 GLN A N   1 
ATOM   868  C  CA  . GLN A 1 124 ? 131.908 148.427 181.115 1.00 172.84 ? 124 GLN A CA  1 
ATOM   869  C  C   . GLN A 1 124 ? 133.050 147.963 180.213 1.00 172.84 ? 124 GLN A C   1 
ATOM   870  O  O   . GLN A 1 124 ? 134.140 147.601 180.672 1.00 172.84 ? 124 GLN A O   1 
ATOM   871  C  CB  . GLN A 1 124 ? 131.187 149.676 180.591 1.00 172.84 ? 124 GLN A CB  1 
ATOM   872  C  CG  . GLN A 1 124 ? 132.031 150.937 180.573 1.00 172.84 ? 124 GLN A CG  1 
ATOM   873  C  CD  . GLN A 1 124 ? 132.165 151.523 179.181 1.00 172.84 ? 124 GLN A CD  1 
ATOM   874  O  OE1 . GLN A 1 124 ? 132.016 150.819 178.183 1.00 172.84 ? 124 GLN A OE1 1 
ATOM   875  N  NE2 . GLN A 1 124 ? 132.439 152.819 179.108 1.00 172.84 ? 124 GLN A NE2 1 
ATOM   876  N  N   . SER A 1 125 ? 132.810 147.956 178.900 1.00 169.99 ? 125 SER A N   1 
ATOM   877  C  CA  . SER A 1 125 ? 133.825 147.465 177.963 1.00 169.99 ? 125 SER A CA  1 
ATOM   878  C  C   . SER A 1 125 ? 133.597 148.139 176.604 1.00 169.99 ? 125 SER A C   1 
ATOM   879  O  O   . SER A 1 125 ? 132.708 147.745 175.849 1.00 169.99 ? 125 SER A O   1 
ATOM   880  C  CB  . SER A 1 125 ? 133.783 145.955 177.846 1.00 169.99 ? 125 SER A CB  1 
ATOM   881  O  OG  . SER A 1 125 ? 132.478 145.504 177.528 1.00 169.99 ? 125 SER A OG  1 
ATOM   882  N  N   . ILE A 1 126 ? 134.412 149.153 176.315 1.00 159.21 ? 126 ILE A N   1 
ATOM   883  C  CA  . ILE A 1 126 ? 134.411 149.806 175.010 1.00 159.21 ? 126 ILE A CA  1 
ATOM   884  C  C   . ILE A 1 126 ? 135.364 149.064 174.083 1.00 159.21 ? 126 ILE A C   1 
ATOM   885  O  O   . ILE A 1 126 ? 136.168 148.240 174.533 1.00 159.21 ? 126 ILE A O   1 
ATOM   886  C  CB  . ILE A 1 126 ? 134.802 151.291 175.114 1.00 159.21 ? 126 ILE A CB  1 
ATOM   887  C  CG1 . ILE A 1 126 ? 135.958 151.466 176.099 1.00 159.21 ? 126 ILE A CG1 1 
ATOM   888  C  CG2 . ILE A 1 126 ? 133.603 152.131 175.528 1.00 159.21 ? 126 ILE A CG2 1 
ATOM   889  C  CD1 . ILE A 1 126 ? 136.384 152.900 176.285 1.00 159.21 ? 126 ILE A CD1 1 
ATOM   890  N  N   . HIS A 1 127 ? 135.281 149.349 172.787 1.00 151.18 ? 127 HIS A N   1 
ATOM   891  C  CA  . HIS A 1 127 ? 136.192 148.751 171.825 1.00 151.18 ? 127 HIS A CA  1 
ATOM   892  C  C   . HIS A 1 127 ? 137.551 149.449 171.873 1.00 151.18 ? 127 HIS A C   1 
ATOM   893  O  O   . HIS A 1 127 ? 137.781 150.380 172.650 1.00 151.18 ? 127 HIS A O   1 
ATOM   894  C  CB  . HIS A 1 127 ? 135.614 148.809 170.407 1.00 151.18 ? 127 HIS A CB  1 
ATOM   895  C  CG  . HIS A 1 127 ? 134.294 148.114 170.245 1.00 151.18 ? 127 HIS A CG  1 
ATOM   896  N  ND1 . HIS A 1 127 ? 133.786 147.777 169.009 1.00 151.18 ? 127 HIS A ND1 1 
ATOM   897  C  CD2 . HIS A 1 127 ? 133.386 147.683 171.153 1.00 151.18 ? 127 HIS A CD2 1 
ATOM   898  C  CE1 . HIS A 1 127 ? 132.620 147.176 169.161 1.00 151.18 ? 127 HIS A CE1 1 
ATOM   899  N  NE2 . HIS A 1 127 ? 132.354 147.107 170.453 1.00 151.18 ? 127 HIS A NE2 1 
ATOM   900  N  N   . ALA A 1 128 ? 138.465 148.980 171.020 1.00 145.05 ? 128 ALA A N   1 
ATOM   901  C  CA  . ALA A 1 128 ? 139.827 149.506 171.026 1.00 145.05 ? 128 ALA A CA  1 
ATOM   902  C  C   . ALA A 1 128 ? 139.887 150.924 170.470 1.00 145.05 ? 128 ALA A C   1 
ATOM   903  O  O   . ALA A 1 128 ? 140.693 151.743 170.927 1.00 145.05 ? 128 ALA A O   1 
ATOM   904  C  CB  . ALA A 1 128 ? 140.748 148.582 170.230 1.00 145.05 ? 128 ALA A CB  1 
ATOM   905  N  N   . ARG A 1 129 ? 139.052 151.229 169.473 1.00 152.41 ? 129 ARG A N   1 
ATOM   906  C  CA  . ARG A 1 129 ? 139.139 152.525 168.804 1.00 152.41 ? 129 ARG A CA  1 
ATOM   907  C  C   . ARG A 1 129 ? 138.685 153.663 169.711 1.00 152.41 ? 129 ARG A C   1 
ATOM   908  O  O   . ARG A 1 129 ? 139.279 154.748 169.697 1.00 152.41 ? 129 ARG A O   1 
ATOM   909  C  CB  . ARG A 1 129 ? 138.315 152.510 167.516 1.00 152.41 ? 129 ARG A CB  1 
ATOM   910  C  CG  . ARG A 1 129 ? 138.970 151.763 166.365 1.00 152.41 ? 129 ARG A CG  1 
ATOM   911  C  CD  . ARG A 1 129 ? 137.941 151.265 165.363 1.00 152.41 ? 129 ARG A CD  1 
ATOM   912  N  NE  . ARG A 1 129 ? 137.264 150.055 165.814 1.00 152.41 ? 129 ARG A NE  1 
ATOM   913  C  CZ  . ARG A 1 129 ? 136.063 150.033 166.375 1.00 152.41 ? 129 ARG A CZ  1 
ATOM   914  N  NH1 . ARG A 1 129 ? 135.372 151.144 166.572 1.00 152.41 ? 129 ARG A NH1 1 
ATOM   915  N  NH2 . ARG A 1 129 ? 135.541 148.868 166.745 1.00 152.41 ? 129 ARG A NH2 1 
ATOM   916  N  N   . GLU A 1 130 ? 137.638 153.440 170.505 1.00 153.93 ? 130 GLU A N   1 
ATOM   917  C  CA  . GLU A 1 130 ? 137.030 154.492 171.312 1.00 153.93 ? 130 GLU A CA  1 
ATOM   918  C  C   . GLU A 1 130 ? 137.580 154.538 172.734 1.00 153.93 ? 130 GLU A C   1 
ATOM   919  O  O   . GLU A 1 130 ? 136.865 154.934 173.661 1.00 153.93 ? 130 GLU A O   1 
ATOM   920  C  CB  . GLU A 1 130 ? 135.509 154.332 171.336 1.00 153.93 ? 130 GLU A CB  1 
ATOM   921  C  CG  . GLU A 1 130 ? 135.027 152.916 171.595 1.00 153.93 ? 130 GLU A CG  1 
ATOM   922  C  CD  . GLU A 1 130 ? 134.710 152.168 170.315 1.00 153.93 ? 130 GLU A CD  1 
ATOM   923  O  OE1 . GLU A 1 130 ? 135.591 152.096 169.432 1.00 153.93 ? 130 GLU A OE1 1 
ATOM   924  O  OE2 . GLU A 1 130 ? 133.579 151.654 170.190 1.00 153.93 ? 130 GLU A OE2 1 
ATOM   925  N  N   . LEU A 1 131 ? 138.834 154.141 172.929 1.00 150.65 ? 131 LEU A N   1 
ATOM   926  C  CA  . LEU A 1 131 ? 139.455 154.269 174.236 1.00 150.65 ? 131 LEU A CA  1 
ATOM   927  C  C   . LEU A 1 131 ? 139.867 155.718 174.492 1.00 150.65 ? 131 LEU A C   1 
ATOM   928  O  O   . LEU A 1 131 ? 139.882 156.561 173.591 1.00 150.65 ? 131 LEU A O   1 
ATOM   929  C  CB  . LEU A 1 131 ? 140.668 153.349 174.354 1.00 150.65 ? 131 LEU A CB  1 
ATOM   930  C  CG  . LEU A 1 131 ? 140.446 151.842 174.237 1.00 150.65 ? 131 LEU A CG  1 
ATOM   931  C  CD1 . LEU A 1 131 ? 141.783 151.134 174.198 1.00 150.65 ? 131 LEU A CD1 1 
ATOM   932  C  CD2 . LEU A 1 131 ? 139.608 151.327 175.391 1.00 150.65 ? 131 LEU A CD2 1 
ATOM   933  N  N   . VAL A 1 132 ? 140.203 156.002 175.746 1.00 148.83 ? 132 VAL A N   1 
ATOM   934  C  CA  . VAL A 1 132 ? 140.671 157.328 176.144 1.00 148.83 ? 132 VAL A CA  1 
ATOM   935  C  C   . VAL A 1 132 ? 141.667 157.161 177.289 1.00 148.83 ? 132 VAL A C   1 
ATOM   936  O  O   . VAL A 1 132 ? 141.496 156.268 178.134 1.00 148.83 ? 132 VAL A O   1 
ATOM   937  C  CB  . VAL A 1 132 ? 139.487 158.245 176.507 1.00 148.83 ? 132 VAL A CB  1 
ATOM   938  C  CG1 . VAL A 1 132 ? 138.768 157.772 177.763 1.00 148.83 ? 132 VAL A CG1 1 
ATOM   939  C  CG2 . VAL A 1 132 ? 139.934 159.691 176.659 1.00 148.83 ? 132 VAL A CG2 1 
ATOM   940  N  N   . PRO A 1 133 ? 142.751 157.936 177.323 1.00 144.91 ? 133 PRO A N   1 
ATOM   941  C  CA  . PRO A 1 133 ? 143.680 157.849 178.454 1.00 144.91 ? 133 PRO A CA  1 
ATOM   942  C  C   . PRO A 1 133 ? 143.044 158.309 179.757 1.00 144.91 ? 133 PRO A C   1 
ATOM   943  O  O   . PRO A 1 133 ? 142.135 159.142 179.775 1.00 144.91 ? 133 PRO A O   1 
ATOM   944  C  CB  . PRO A 1 133 ? 144.829 158.776 178.043 1.00 144.91 ? 133 PRO A CB  1 
ATOM   945  C  CG  . PRO A 1 133 ? 144.781 158.792 176.558 1.00 144.91 ? 133 PRO A CG  1 
ATOM   946  C  CD  . PRO A 1 133 ? 143.329 158.689 176.195 1.00 144.91 ? 133 PRO A CD  1 
ATOM   947  N  N   . GLY A 1 134 ? 143.539 157.751 180.855 1.00 146.08 ? 134 GLY A N   1 
ATOM   948  C  CA  . GLY A 1 134 ? 143.096 158.133 182.177 1.00 146.08 ? 134 GLY A CA  1 
ATOM   949  C  C   . GLY A 1 134 ? 142.013 157.277 182.798 1.00 146.08 ? 134 GLY A C   1 
ATOM   950  O  O   . GLY A 1 134 ? 141.388 157.720 183.768 1.00 146.08 ? 134 GLY A O   1 
ATOM   951  N  N   . ASP A 1 135 ? 141.771 156.075 182.280 1.00 155.74 ? 135 ASP A N   1 
ATOM   952  C  CA  . ASP A 1 135 ? 140.737 155.199 182.808 1.00 155.74 ? 135 ASP A CA  1 
ATOM   953  C  C   . ASP A 1 135 ? 141.308 153.808 183.047 1.00 155.74 ? 135 ASP A C   1 
ATOM   954  O  O   . ASP A 1 135 ? 142.170 153.335 182.301 1.00 155.74 ? 135 ASP A O   1 
ATOM   955  C  CB  . ASP A 1 135 ? 139.533 155.122 181.863 1.00 155.74 ? 135 ASP A CB  1 
ATOM   956  C  CG  . ASP A 1 135 ? 138.885 156.475 181.641 1.00 155.74 ? 135 ASP A CG  1 
ATOM   957  O  OD1 . ASP A 1 135 ? 139.486 157.313 180.938 1.00 155.74 ? 135 ASP A OD1 1 
ATOM   958  O  OD2 . ASP A 1 135 ? 137.782 156.705 182.179 1.00 155.74 ? 135 ASP A OD2 1 
ATOM   959  N  N   . VAL A 1 136 ? 140.815 153.160 184.098 1.00 160.96 ? 136 VAL A N   1 
ATOM   960  C  CA  . VAL A 1 136 ? 141.337 151.865 184.520 1.00 160.96 ? 136 VAL A CA  1 
ATOM   961  C  C   . VAL A 1 136 ? 140.824 150.783 183.580 1.00 160.96 ? 136 VAL A C   1 
ATOM   962  O  O   . VAL A 1 136 ? 139.628 150.726 183.269 1.00 160.96 ? 136 VAL A O   1 
ATOM   963  C  CB  . VAL A 1 136 ? 140.939 151.567 185.975 1.00 160.96 ? 136 VAL A CB  1 
ATOM   964  C  CG1 . VAL A 1 136 ? 141.878 150.535 186.580 1.00 160.96 ? 136 VAL A CG1 1 
ATOM   965  C  CG2 . VAL A 1 136 ? 140.921 152.845 186.800 1.00 160.96 ? 136 VAL A CG2 1 
ATOM   966  N  N   . VAL A 1 137 ? 141.730 149.922 183.121 1.00 154.08 ? 137 VAL A N   1 
ATOM   967  C  CA  . VAL A 1 137 ? 141.402 148.821 182.223 1.00 154.08 ? 137 VAL A CA  1 
ATOM   968  C  C   . VAL A 1 137 ? 141.929 147.530 182.832 1.00 154.08 ? 137 VAL A C   1 
ATOM   969  O  O   . VAL A 1 137 ? 143.103 147.451 183.208 1.00 154.08 ? 137 VAL A O   1 
ATOM   970  C  CB  . VAL A 1 137 ? 141.994 149.033 180.816 1.00 154.08 ? 137 VAL A CB  1 
ATOM   971  C  CG1 . VAL A 1 137 ? 141.697 147.838 179.922 1.00 154.08 ? 137 VAL A CG1 1 
ATOM   972  C  CG2 . VAL A 1 137 ? 141.456 150.310 180.198 1.00 154.08 ? 137 VAL A CG2 1 
ATOM   973  N  N   . ILE A 1 138 ? 141.067 146.521 182.925 1.00 152.50 ? 138 ILE A N   1 
ATOM   974  C  CA  . ILE A 1 138 ? 141.442 145.208 183.437 1.00 152.50 ? 138 ILE A CA  1 
ATOM   975  C  C   . ILE A 1 138 ? 141.759 144.301 182.256 1.00 152.50 ? 138 ILE A C   1 
ATOM   976  O  O   . ILE A 1 138 ? 140.959 144.178 181.320 1.00 152.50 ? 138 ILE A O   1 
ATOM   977  C  CB  . ILE A 1 138 ? 140.331 144.615 184.325 1.00 152.50 ? 138 ILE A CB  1 
ATOM   978  C  CG1 . ILE A 1 138 ? 140.583 143.131 184.612 1.00 152.50 ? 138 ILE A CG1 1 
ATOM   979  C  CG2 . ILE A 1 138 ? 138.951 144.850 183.720 1.00 152.50 ? 138 ILE A CG2 1 
ATOM   980  C  CD1 . ILE A 1 138 ? 141.842 142.863 185.410 1.00 152.50 ? 138 ILE A CD1 1 
ATOM   981  N  N   . LEU A 1 139 ? 142.937 143.680 182.287 1.00 144.04 ? 139 LEU A N   1 
ATOM   982  C  CA  . LEU A 1 139 ? 143.365 142.741 181.256 1.00 144.04 ? 139 LEU A CA  1 
ATOM   983  C  C   . LEU A 1 139 ? 143.429 141.350 181.868 1.00 144.04 ? 139 LEU A C   1 
ATOM   984  O  O   . LEU A 1 139 ? 144.279 141.082 182.724 1.00 144.04 ? 139 LEU A O   1 
ATOM   985  C  CB  . LEU A 1 139 ? 144.722 143.128 180.670 1.00 144.04 ? 139 LEU A CB  1 
ATOM   986  C  CG  . LEU A 1 139 ? 145.000 144.591 180.339 1.00 144.04 ? 139 LEU A CG  1 
ATOM   987  C  CD1 . LEU A 1 139 ? 146.498 144.795 180.184 1.00 144.04 ? 139 LEU A CD1 1 
ATOM   988  C  CD2 . LEU A 1 139 ? 144.261 145.008 179.079 1.00 144.04 ? 139 LEU A CD2 1 
ATOM   989  N  N   . ASP A 1 140 ? 142.535 140.470 181.431 1.00 137.02 ? 140 ASP A N   1 
ATOM   990  C  CA  . ASP A 1 140 ? 142.619 139.069 181.802 1.00 137.02 ? 140 ASP A CA  1 
ATOM   991  C  C   . ASP A 1 140 ? 143.659 138.373 180.927 1.00 137.02 ? 140 ASP A C   1 
ATOM   992  O  O   . ASP A 1 140 ? 144.319 138.992 180.087 1.00 137.02 ? 140 ASP A O   1 
ATOM   993  C  CB  . ASP A 1 140 ? 141.251 138.402 181.679 1.00 137.02 ? 140 ASP A CB  1 
ATOM   994  C  CG  . ASP A 1 140 ? 140.438 138.503 182.953 1.00 137.02 ? 140 ASP A CG  1 
ATOM   995  O  OD1 . ASP A 1 140 ? 140.760 137.786 183.924 1.00 137.02 ? 140 ASP A OD1 1 
ATOM   996  O  OD2 . ASP A 1 140 ? 139.478 139.300 182.984 1.00 137.02 ? 140 ASP A OD2 1 
ATOM   997  N  N   . ALA A 1 141 ? 143.814 137.069 181.129 1.00 119.14 ? 141 ALA A N   1 
ATOM   998  C  CA  . ALA A 1 141 ? 144.723 136.288 180.302 1.00 119.14 ? 141 ALA A CA  1 
ATOM   999  C  C   . ALA A 1 141 ? 144.181 136.214 178.879 1.00 119.14 ? 141 ALA A C   1 
ATOM   1000 O  O   . ALA A 1 141 ? 143.057 135.750 178.659 1.00 119.14 ? 141 ALA A O   1 
ATOM   1001 C  CB  . ALA A 1 141 ? 144.905 134.891 180.887 1.00 119.14 ? 141 ALA A CB  1 
ATOM   1002 N  N   . GLY A 1 142 ? 144.978 136.671 177.915 1.00 111.22 ? 142 GLY A N   1 
ATOM   1003 C  CA  . GLY A 1 142 ? 144.596 136.664 176.520 1.00 111.22 ? 142 GLY A CA  1 
ATOM   1004 C  C   . GLY A 1 142 ? 143.895 137.916 176.040 1.00 111.22 ? 142 GLY A C   1 
ATOM   1005 O  O   . GLY A 1 142 ? 143.652 138.044 174.834 1.00 111.22 ? 142 GLY A O   1 
ATOM   1006 N  N   . ASP A 1 143 ? 143.558 138.837 176.940 1.00 132.38 ? 143 ASP A N   1 
ATOM   1007 C  CA  . ASP A 1 143 ? 142.938 140.104 176.556 1.00 132.38 ? 143 ASP A CA  1 
ATOM   1008 C  C   . ASP A 1 143 ? 144.034 141.033 176.053 1.00 132.38 ? 143 ASP A C   1 
ATOM   1009 O  O   . ASP A 1 143 ? 144.748 141.653 176.844 1.00 132.38 ? 143 ASP A O   1 
ATOM   1010 C  CB  . ASP A 1 143 ? 142.185 140.712 177.733 1.00 132.38 ? 143 ASP A CB  1 
ATOM   1011 C  CG  . ASP A 1 143 ? 141.630 142.088 177.424 1.00 132.38 ? 143 ASP A CG  1 
ATOM   1012 O  OD1 . ASP A 1 143 ? 141.142 142.295 176.293 1.00 132.38 ? 143 ASP A OD1 1 
ATOM   1013 O  OD2 . ASP A 1 143 ? 141.680 142.964 178.313 1.00 132.38 ? 143 ASP A OD2 1 
ATOM   1014 N  N   . PHE A 1 144 ? 144.164 141.136 174.731 1.00 127.38 ? 144 PHE A N   1 
ATOM   1015 C  CA  . PHE A 1 144 ? 145.248 141.901 174.124 1.00 127.38 ? 144 PHE A CA  1 
ATOM   1016 C  C   . PHE A 1 144 ? 145.054 143.383 174.430 1.00 127.38 ? 144 PHE A C   1 
ATOM   1017 O  O   . PHE A 1 144 ? 143.997 143.954 174.140 1.00 127.38 ? 144 PHE A O   1 
ATOM   1018 C  CB  . PHE A 1 144 ? 145.284 141.628 172.617 1.00 127.38 ? 144 PHE A CB  1 
ATOM   1019 C  CG  . PHE A 1 144 ? 145.575 142.836 171.762 1.00 127.38 ? 144 PHE A CG  1 
ATOM   1020 C  CD1 . PHE A 1 144 ? 146.844 143.397 171.724 1.00 127.38 ? 144 PHE A CD1 1 
ATOM   1021 C  CD2 . PHE A 1 144 ? 144.579 143.402 170.985 1.00 127.38 ? 144 PHE A CD2 1 
ATOM   1022 C  CE1 . PHE A 1 144 ? 147.108 144.498 170.933 1.00 127.38 ? 144 PHE A CE1 1 
ATOM   1023 C  CE2 . PHE A 1 144 ? 144.838 144.506 170.194 1.00 127.38 ? 144 PHE A CE2 1 
ATOM   1024 C  CZ  . PHE A 1 144 ? 146.103 145.054 170.169 1.00 127.38 ? 144 PHE A CZ  1 
ATOM   1025 N  N   . VAL A 1 145 ? 146.068 143.999 175.033 1.00 134.12 ? 145 VAL A N   1 
ATOM   1026 C  CA  . VAL A 1 145 ? 145.972 145.381 175.498 1.00 134.12 ? 145 VAL A CA  1 
ATOM   1027 C  C   . VAL A 1 145 ? 146.064 146.333 174.309 1.00 134.12 ? 145 VAL A C   1 
ATOM   1028 O  O   . VAL A 1 145 ? 147.025 146.273 173.528 1.00 134.12 ? 145 VAL A O   1 
ATOM   1029 C  CB  . VAL A 1 145 ? 147.032 145.677 176.575 1.00 134.12 ? 145 VAL A CB  1 
ATOM   1030 C  CG1 . VAL A 1 145 ? 148.432 145.265 176.125 1.00 134.12 ? 145 VAL A CG1 1 
ATOM   1031 C  CG2 . VAL A 1 145 ? 147.004 147.142 176.953 1.00 134.12 ? 145 VAL A CG2 1 
ATOM   1032 N  N   . PRO A 1 146 ? 145.076 147.206 174.116 1.00 137.94 ? 146 PRO A N   1 
ATOM   1033 C  CA  . PRO A 1 146 ? 145.059 148.045 172.910 1.00 137.94 ? 146 PRO A CA  1 
ATOM   1034 C  C   . PRO A 1 146 ? 145.852 149.338 173.041 1.00 137.94 ? 146 PRO A C   1 
ATOM   1035 O  O   . PRO A 1 146 ? 146.320 149.877 172.034 1.00 137.94 ? 146 PRO A O   1 
ATOM   1036 C  CB  . PRO A 1 146 ? 143.563 148.334 172.705 1.00 137.94 ? 146 PRO A CB  1 
ATOM   1037 C  CG  . PRO A 1 146 ? 142.827 147.511 173.757 1.00 137.94 ? 146 PRO A CG  1 
ATOM   1038 C  CD  . PRO A 1 146 ? 143.809 147.295 174.855 1.00 137.94 ? 146 PRO A CD  1 
ATOM   1039 N  N   . ALA A 1 147 ? 146.004 149.852 174.260 1.00 139.89 ? 147 ALA A N   1 
ATOM   1040 C  CA  . ALA A 1 147 ? 146.659 151.136 174.470 1.00 139.89 ? 147 ALA A CA  1 
ATOM   1041 C  C   . ALA A 1 147 ? 147.642 151.037 175.627 1.00 139.89 ? 147 ALA A C   1 
ATOM   1042 O  O   . ALA A 1 147 ? 147.402 150.328 176.607 1.00 139.89 ? 147 ALA A O   1 
ATOM   1043 C  CB  . ALA A 1 147 ? 145.639 152.248 174.745 1.00 139.89 ? 147 ALA A CB  1 
ATOM   1044 N  N   . ASP A 1 148 ? 148.750 151.766 175.506 1.00 142.93 ? 148 ASP A N   1 
ATOM   1045 C  CA  . ASP A 1 148 ? 149.764 151.774 176.550 1.00 142.93 ? 148 ASP A CA  1 
ATOM   1046 C  C   . ASP A 1 148 ? 149.237 152.469 177.801 1.00 142.93 ? 148 ASP A C   1 
ATOM   1047 O  O   . ASP A 1 148 ? 148.404 153.377 177.731 1.00 142.93 ? 148 ASP A O   1 
ATOM   1048 C  CB  . ASP A 1 148 ? 151.043 152.456 176.049 1.00 142.93 ? 148 ASP A CB  1 
ATOM   1049 C  CG  . ASP A 1 148 ? 151.020 153.970 176.213 1.00 142.93 ? 148 ASP A CG  1 
ATOM   1050 O  OD1 . ASP A 1 148 ? 151.362 154.469 177.308 1.00 142.93 ? 148 ASP A OD1 1 
ATOM   1051 O  OD2 . ASP A 1 148 ? 150.658 154.667 175.243 1.00 142.93 ? 148 ASP A OD2 1 
ATOM   1052 N  N   . GLY A 1 149 ? 149.723 152.025 178.958 1.00 151.24 ? 149 GLY A N   1 
ATOM   1053 C  CA  . GLY A 1 149 ? 149.309 152.643 180.201 1.00 151.24 ? 149 GLY A CA  1 
ATOM   1054 C  C   . GLY A 1 149 ? 149.972 152.119 181.459 1.00 151.24 ? 149 GLY A C   1 
ATOM   1055 O  O   . GLY A 1 149 ? 150.453 150.983 181.498 1.00 151.24 ? 149 GLY A O   1 
ATOM   1056 N  N   . ARG A 1 150 ? 149.962 152.940 182.506 1.00 153.37 ? 150 ARG A N   1 
ATOM   1057 C  CA  . ARG A 1 150 ? 150.662 152.621 183.743 1.00 153.37 ? 150 ARG A CA  1 
ATOM   1058 C  C   . ARG A 1 150 ? 149.931 151.536 184.525 1.00 153.37 ? 150 ARG A C   1 
ATOM   1059 O  O   . ARG A 1 150 ? 148.706 151.568 184.672 1.00 153.37 ? 150 ARG A O   1 
ATOM   1060 C  CB  . ARG A 1 150 ? 150.807 153.885 184.595 1.00 153.37 ? 150 ARG A CB  1 
ATOM   1061 C  CG  . ARG A 1 150 ? 151.056 153.651 186.078 1.00 153.37 ? 150 ARG A CG  1 
ATOM   1062 C  CD  . ARG A 1 150 ? 152.467 153.155 186.340 1.00 153.37 ? 150 ARG A CD  1 
ATOM   1063 N  NE  . ARG A 1 150 ? 152.823 153.249 187.750 1.00 153.37 ? 150 ARG A NE  1 
ATOM   1064 C  CZ  . ARG A 1 150 ? 153.767 152.524 188.335 1.00 153.37 ? 150 ARG A CZ  1 
ATOM   1065 N  NH1 . ARG A 1 150 ? 154.475 151.634 187.658 1.00 153.37 ? 150 ARG A NH1 1 
ATOM   1066 N  NH2 . ARG A 1 150 ? 154.009 152.698 189.631 1.00 153.37 ? 150 ARG A NH2 1 
ATOM   1067 N  N   . LEU A 1 151 ? 150.696 150.572 185.031 1.00 150.09 ? 151 LEU A N   1 
ATOM   1068 C  CA  . LEU A 1 151 ? 150.176 149.483 185.845 1.00 150.09 ? 151 LEU A CA  1 
ATOM   1069 C  C   . LEU A 1 151 ? 150.558 149.696 187.305 1.00 150.09 ? 151 LEU A C   1 
ATOM   1070 O  O   . LEU A 1 151 ? 151.680 150.113 187.608 1.00 150.09 ? 151 LEU A O   1 
ATOM   1071 C  CB  . LEU A 1 151 ? 150.721 148.139 185.360 1.00 150.09 ? 151 LEU A CB  1 
ATOM   1072 C  CG  . LEU A 1 151 ? 150.368 146.912 186.201 1.00 150.09 ? 151 LEU A CG  1 
ATOM   1073 C  CD1 . LEU A 1 151 ? 149.205 146.142 185.591 1.00 150.09 ? 151 LEU A CD1 1 
ATOM   1074 C  CD2 . LEU A 1 151 ? 151.588 146.030 186.393 1.00 150.09 ? 151 LEU A CD2 1 
ATOM   1075 N  N   . PHE A 1 152 ? 149.618 149.411 188.208 1.00 152.72 ? 152 PHE A N   1 
ATOM   1076 C  CA  . PHE A 1 152 ? 149.865 149.534 189.642 1.00 152.72 ? 152 PHE A CA  1 
ATOM   1077 C  C   . PHE A 1 152 ? 150.083 148.176 190.308 1.00 152.72 ? 152 PHE A C   1 
ATOM   1078 O  O   . PHE A 1 152 ? 151.124 147.953 190.933 1.00 152.72 ? 152 PHE A O   1 
ATOM   1079 C  CB  . PHE A 1 152 ? 148.721 150.312 190.318 1.00 152.72 ? 152 PHE A CB  1 
ATOM   1080 C  CG  . PHE A 1 152 ? 147.361 150.092 189.699 1.00 152.72 ? 152 PHE A CG  1 
ATOM   1081 C  CD1 . PHE A 1 152 ? 146.913 150.899 188.663 1.00 152.72 ? 152 PHE A CD1 1 
ATOM   1082 C  CD2 . PHE A 1 152 ? 146.520 149.099 190.173 1.00 152.72 ? 152 PHE A CD2 1 
ATOM   1083 C  CE1 . PHE A 1 152 ? 145.666 150.703 188.102 1.00 152.72 ? 152 PHE A CE1 1 
ATOM   1084 C  CE2 . PHE A 1 152 ? 145.273 148.902 189.617 1.00 152.72 ? 152 PHE A CE2 1 
ATOM   1085 C  CZ  . PHE A 1 152 ? 144.845 149.704 188.581 1.00 152.72 ? 152 PHE A CZ  1 
ATOM   1086 N  N   . GLU A 1 153 ? 149.129 147.255 190.183 1.00 150.94 ? 153 GLU A N   1 
ATOM   1087 C  CA  . GLU A 1 153 ? 149.298 145.896 190.684 1.00 150.94 ? 153 GLU A CA  1 
ATOM   1088 C  C   . GLU A 1 153 ? 148.963 144.886 189.598 1.00 150.94 ? 153 GLU A C   1 
ATOM   1089 O  O   . GLU A 1 153 ? 148.051 145.100 188.794 1.00 150.94 ? 153 GLU A O   1 
ATOM   1090 C  CB  . GLU A 1 153 ? 148.433 145.602 191.929 1.00 150.94 ? 153 GLU A CB  1 
ATOM   1091 C  CG  . GLU A 1 153 ? 148.971 146.136 193.259 1.00 150.94 ? 153 GLU A CG  1 
ATOM   1092 C  CD  . GLU A 1 153 ? 148.949 147.644 193.372 1.00 150.94 ? 153 GLU A CD  1 
ATOM   1093 O  OE1 . GLU A 1 153 ? 149.744 148.195 194.161 1.00 150.94 ? 153 GLU A OE1 1 
ATOM   1094 O  OE2 . GLU A 1 153 ? 148.108 148.277 192.707 1.00 150.94 ? 153 GLU A OE2 1 
ATOM   1095 N  N   . SER A 1 154 ? 149.710 143.783 189.586 1.00 140.59 ? 154 SER A N   1 
ATOM   1096 C  CA  . SER A 1 154 ? 149.451 142.663 188.693 1.00 140.59 ? 154 SER A CA  1 
ATOM   1097 C  C   . SER A 1 154 ? 150.102 141.418 189.274 1.00 140.59 ? 154 SER A C   1 
ATOM   1098 O  O   . SER A 1 154 ? 151.200 141.492 189.833 1.00 140.59 ? 154 SER A O   1 
ATOM   1099 C  CB  . SER A 1 154 ? 149.986 142.925 187.282 1.00 140.59 ? 154 SER A CB  1 
ATOM   1100 O  OG  . SER A 1 154 ? 151.383 142.699 187.219 1.00 140.59 ? 154 SER A OG  1 
ATOM   1101 N  N   . GLY A 1 155 ? 149.422 140.283 189.142 1.00 134.61 ? 155 GLY A N   1 
ATOM   1102 C  CA  . GLY A 1 155 ? 149.987 139.026 189.587 1.00 134.61 ? 155 GLY A CA  1 
ATOM   1103 C  C   . GLY A 1 155 ? 150.606 138.229 188.458 1.00 134.61 ? 155 GLY A C   1 
ATOM   1104 O  O   . GLY A 1 155 ? 149.894 137.537 187.722 1.00 134.61 ? 155 GLY A O   1 
ATOM   1105 N  N   . SER A 1 156 ? 151.932 138.314 188.329 1.00 139.93 ? 156 SER A N   1 
ATOM   1106 C  CA  . SER A 1 156 ? 152.713 137.610 187.307 1.00 139.93 ? 156 SER A CA  1 
ATOM   1107 C  C   . SER A 1 156 ? 152.189 137.911 185.902 1.00 139.93 ? 156 SER A C   1 
ATOM   1108 O  O   . SER A 1 156 ? 151.728 137.031 185.173 1.00 139.93 ? 156 SER A O   1 
ATOM   1109 C  CB  . SER A 1 156 ? 152.738 136.102 187.576 1.00 139.93 ? 156 SER A CB  1 
ATOM   1110 O  OG  . SER A 1 156 ? 151.490 135.506 187.267 1.00 139.93 ? 156 SER A OG  1 
ATOM   1111 N  N   . LEU A 1 157 ? 152.273 139.186 185.529 1.00 139.02 ? 157 LEU A N   1 
ATOM   1112 C  CA  . LEU A 1 157 ? 151.733 139.660 184.255 1.00 139.02 ? 157 LEU A CA  1 
ATOM   1113 C  C   . LEU A 1 157 ? 152.717 139.318 183.143 1.00 139.02 ? 157 LEU A C   1 
ATOM   1114 O  O   . LEU A 1 157 ? 153.562 140.126 182.756 1.00 139.02 ? 157 LEU A O   1 
ATOM   1115 C  CB  . LEU A 1 157 ? 151.453 141.156 184.313 1.00 139.02 ? 157 LEU A CB  1 
ATOM   1116 C  CG  . LEU A 1 157 ? 150.474 141.695 183.269 1.00 139.02 ? 157 LEU A CG  1 
ATOM   1117 C  CD1 . LEU A 1 157 ? 149.171 140.911 183.298 1.00 139.02 ? 157 LEU A CD1 1 
ATOM   1118 C  CD2 . LEU A 1 157 ? 150.217 143.178 183.489 1.00 139.02 ? 157 LEU A CD2 1 
ATOM   1119 N  N   . LYS A 1 158 ? 152.603 138.098 182.621 1.00 137.02 ? 158 LYS A N   1 
ATOM   1120 C  CA  . LYS A 1 158 ? 153.442 137.657 181.511 1.00 137.02 ? 158 LYS A CA  1 
ATOM   1121 C  C   . LYS A 1 158 ? 153.014 138.376 180.237 1.00 137.02 ? 158 LYS A C   1 
ATOM   1122 O  O   . LYS A 1 158 ? 151.977 138.053 179.649 1.00 137.02 ? 158 LYS A O   1 
ATOM   1123 C  CB  . LYS A 1 158 ? 153.348 136.143 181.345 1.00 137.02 ? 158 LYS A CB  1 
ATOM   1124 C  CG  . LYS A 1 158 ? 154.350 135.360 182.182 1.00 137.02 ? 158 LYS A CG  1 
ATOM   1125 C  CD  . LYS A 1 158 ? 153.778 135.002 183.543 1.00 137.02 ? 158 LYS A CD  1 
ATOM   1126 C  CE  . LYS A 1 158 ? 154.861 134.486 184.475 1.00 137.02 ? 158 LYS A CE  1 
ATOM   1127 N  NZ  . LYS A 1 158 ? 154.297 133.767 185.651 1.00 137.02 ? 158 LYS A NZ  1 
ATOM   1128 N  N   . ILE A 1 159 ? 153.808 139.356 179.812 1.00 137.90 ? 159 ILE A N   1 
ATOM   1129 C  CA  . ILE A 1 159 ? 153.511 140.170 178.639 1.00 137.90 ? 159 ILE A CA  1 
ATOM   1130 C  C   . ILE A 1 159 ? 154.654 139.997 177.650 1.00 137.90 ? 159 ILE A C   1 
ATOM   1131 O  O   . ILE A 1 159 ? 155.800 140.356 177.950 1.00 137.90 ? 159 ILE A O   1 
ATOM   1132 C  CB  . ILE A 1 159 ? 153.327 141.649 179.001 1.00 137.90 ? 159 ILE A CB  1 
ATOM   1133 C  CG1 . ILE A 1 159 ? 152.197 141.819 180.015 1.00 137.90 ? 159 ILE A CG1 1 
ATOM   1134 C  CG2 . ILE A 1 159 ? 153.063 142.469 177.753 1.00 137.90 ? 159 ILE A CG2 1 
ATOM   1135 C  CD1 . ILE A 1 159 ? 150.833 141.588 179.453 1.00 137.90 ? 159 ILE A CD1 1 
ATOM   1136 N  N   . ASP A 1 160 ? 154.350 139.458 176.473 1.00 146.57 ? 160 ASP A N   1 
ATOM   1137 C  CA  . ASP A 1 160 ? 155.327 139.386 175.395 1.00 146.57 ? 160 ASP A CA  1 
ATOM   1138 C  C   . ASP A 1 160 ? 155.179 140.597 174.483 1.00 146.57 ? 160 ASP A C   1 
ATOM   1139 O  O   . ASP A 1 160 ? 154.076 141.120 174.295 1.00 146.57 ? 160 ASP A O   1 
ATOM   1140 C  CB  . ASP A 1 160 ? 155.171 138.090 174.595 1.00 146.57 ? 160 ASP A CB  1 
ATOM   1141 C  CG  . ASP A 1 160 ? 153.978 138.115 173.664 1.00 146.57 ? 160 ASP A CG  1 
ATOM   1142 O  OD1 . ASP A 1 160 ? 152.877 138.473 174.128 1.00 146.57 ? 160 ASP A OD1 1 
ATOM   1143 O  OD2 . ASP A 1 160 ? 154.140 137.778 172.472 1.00 146.57 ? 160 ASP A OD2 1 
ATOM   1144 N  N   . GLU A 1 161 ? 156.301 141.046 173.926 1.00 152.90 ? 161 GLU A N   1 
ATOM   1145 C  CA  . GLU A 1 161 ? 156.364 142.261 173.121 1.00 152.90 ? 161 GLU A CA  1 
ATOM   1146 C  C   . GLU A 1 161 ? 157.040 141.978 171.785 1.00 152.90 ? 161 GLU A C   1 
ATOM   1147 O  O   . GLU A 1 161 ? 157.920 142.714 171.332 1.00 152.90 ? 161 GLU A O   1 
ATOM   1148 C  CB  . GLU A 1 161 ? 157.091 143.368 173.881 1.00 152.90 ? 161 GLU A CB  1 
ATOM   1149 C  CG  . GLU A 1 161 ? 156.336 143.883 175.100 1.00 152.90 ? 161 GLU A CG  1 
ATOM   1150 C  CD  . GLU A 1 161 ? 157.258 144.413 176.182 1.00 152.90 ? 161 GLU A CD  1 
ATOM   1151 O  OE1 . GLU A 1 161 ? 158.337 143.818 176.386 1.00 152.90 ? 161 GLU A OE1 1 
ATOM   1152 O  OE2 . GLU A 1 161 ? 156.901 145.418 176.832 1.00 152.90 ? 161 GLU A OE2 1 
ATOM   1153 N  N   . GLY A 1 162 ? 156.625 140.891 171.130 1.00 155.39 ? 162 GLY A N   1 
ATOM   1154 C  CA  . GLY A 1 162 ? 157.215 140.519 169.855 1.00 155.39 ? 162 GLY A CA  1 
ATOM   1155 C  C   . GLY A 1 162 ? 156.845 141.434 168.706 1.00 155.39 ? 162 GLY A C   1 
ATOM   1156 O  O   . GLY A 1 162 ? 157.559 141.466 167.698 1.00 155.39 ? 162 GLY A O   1 
ATOM   1157 N  N   . MET A 1 163 ? 155.752 142.185 168.835 1.00 150.74 ? 163 MET A N   1 
ATOM   1158 C  CA  . MET A 1 163 ? 155.312 143.098 167.788 1.00 150.74 ? 163 MET A CA  1 
ATOM   1159 C  C   . MET A 1 163 ? 155.651 144.554 168.073 1.00 150.74 ? 163 MET A C   1 
ATOM   1160 O  O   . MET A 1 163 ? 155.947 145.302 167.137 1.00 150.74 ? 163 MET A O   1 
ATOM   1161 C  CB  . MET A 1 163 ? 153.798 142.975 167.575 1.00 150.74 ? 163 MET A CB  1 
ATOM   1162 C  CG  . MET A 1 163 ? 153.275 141.943 166.544 1.00 150.74 ? 163 MET A CG  1 
ATOM   1163 S  SD  . MET A 1 163 ? 154.031 141.723 164.903 1.00 150.74 ? 163 MET A SD  1 
ATOM   1164 C  CE  . MET A 1 163 ? 155.505 140.745 165.204 1.00 150.74 ? 163 MET A CE  1 
ATOM   1165 N  N   . LEU A 1 164 ? 155.603 144.975 169.339 1.00 147.29 ? 164 LEU A N   1 
ATOM   1166 C  CA  . LEU A 1 164 ? 155.930 146.357 169.676 1.00 147.29 ? 164 LEU A CA  1 
ATOM   1167 C  C   . LEU A 1 164 ? 157.409 146.649 169.445 1.00 147.29 ? 164 LEU A C   1 
ATOM   1168 O  O   . LEU A 1 164 ? 157.764 147.639 168.794 1.00 147.29 ? 164 LEU A O   1 
ATOM   1169 C  CB  . LEU A 1 164 ? 155.550 146.640 171.128 1.00 147.29 ? 164 LEU A CB  1 
ATOM   1170 C  CG  . LEU A 1 164 ? 156.250 147.822 171.799 1.00 147.29 ? 164 LEU A CG  1 
ATOM   1171 C  CD1 . LEU A 1 164 ? 155.596 149.148 171.413 1.00 147.29 ? 164 LEU A CD1 1 
ATOM   1172 C  CD2 . LEU A 1 164 ? 156.291 147.629 173.306 1.00 147.29 ? 164 LEU A CD2 1 
ATOM   1173 N  N   . THR A 1 165 ? 158.289 145.792 169.970 1.00 160.85 ? 165 THR A N   1 
ATOM   1174 C  CA  . THR A 1 165 ? 159.724 146.016 169.845 1.00 160.85 ? 165 THR A CA  1 
ATOM   1175 C  C   . THR A 1 165 ? 160.499 144.736 169.553 1.00 160.85 ? 165 THR A C   1 
ATOM   1176 O  O   . THR A 1 165 ? 161.733 144.745 169.646 1.00 160.85 ? 165 THR A O   1 
ATOM   1177 C  CB  . THR A 1 165 ? 160.277 146.671 171.117 1.00 160.85 ? 165 THR A CB  1 
ATOM   1178 O  OG1 . THR A 1 165 ? 161.706 146.747 171.037 1.00 160.85 ? 165 THR A OG1 1 
ATOM   1179 C  CG2 . THR A 1 165 ? 159.885 145.864 172.344 1.00 160.85 ? 165 THR A CG2 1 
ATOM   1180 N  N   . GLY A 1 166 ? 159.825 143.642 169.206 1.00 161.21 ? 166 GLY A N   1 
ATOM   1181 C  CA  . GLY A 1 166 ? 160.517 142.397 168.942 1.00 161.21 ? 166 GLY A CA  1 
ATOM   1182 C  C   . GLY A 1 166 ? 161.054 141.699 170.168 1.00 161.21 ? 166 GLY A C   1 
ATOM   1183 O  O   . GLY A 1 166 ? 161.928 140.837 170.044 1.00 161.21 ? 166 GLY A O   1 
ATOM   1184 N  N   . GLU A 1 167 ? 160.556 142.044 171.353 1.00 158.98 ? 167 GLU A N   1 
ATOM   1185 C  CA  . GLU A 1 167 ? 161.007 141.426 172.598 1.00 158.98 ? 167 GLU A CA  1 
ATOM   1186 C  C   . GLU A 1 167 ? 160.237 140.128 172.801 1.00 158.98 ? 167 GLU A C   1 
ATOM   1187 O  O   . GLU A 1 167 ? 159.088 140.135 173.249 1.00 158.98 ? 167 GLU A O   1 
ATOM   1188 C  CB  . GLU A 1 167 ? 160.812 142.379 173.772 1.00 158.98 ? 167 GLU A CB  1 
ATOM   1189 C  CG  . GLU A 1 167 ? 162.093 142.714 174.518 1.00 158.98 ? 167 GLU A CG  1 
ATOM   1190 C  CD  . GLU A 1 167 ? 161.849 143.580 175.737 1.00 158.98 ? 167 GLU A CD  1 
ATOM   1191 O  OE1 . GLU A 1 167 ? 161.074 144.554 175.630 1.00 158.98 ? 167 GLU A OE1 1 
ATOM   1192 O  OE2 . GLU A 1 167 ? 162.432 143.288 176.802 1.00 158.98 ? 167 GLU A OE2 1 
ATOM   1193 N  N   . SER A 1 168 ? 160.875 139.003 172.471 1.00 157.18 ? 168 SER A N   1 
ATOM   1194 C  CA  . SER A 1 168 ? 160.220 137.706 172.591 1.00 157.18 ? 168 SER A CA  1 
ATOM   1195 C  C   . SER A 1 168 ? 160.046 137.267 174.040 1.00 157.18 ? 168 SER A C   1 
ATOM   1196 O  O   . SER A 1 168 ? 159.212 136.397 174.311 1.00 157.18 ? 168 SER A O   1 
ATOM   1197 C  CB  . SER A 1 168 ? 161.008 136.649 171.817 1.00 157.18 ? 168 SER A CB  1 
ATOM   1198 O  OG  . SER A 1 168 ? 162.261 136.397 172.429 1.00 157.18 ? 168 SER A OG  1 
ATOM   1199 N  N   . GLU A 1 169 ? 160.811 137.839 174.967 1.00 152.67 ? 169 GLU A N   1 
ATOM   1200 C  CA  . GLU A 1 169 ? 160.697 137.473 176.371 1.00 152.67 ? 169 GLU A CA  1 
ATOM   1201 C  C   . GLU A 1 169 ? 159.408 138.021 176.975 1.00 152.67 ? 169 GLU A C   1 
ATOM   1202 O  O   . GLU A 1 169 ? 158.895 139.066 176.563 1.00 152.67 ? 169 GLU A O   1 
ATOM   1203 C  CB  . GLU A 1 169 ? 161.907 137.984 177.156 1.00 152.67 ? 169 GLU A CB  1 
ATOM   1204 C  CG  . GLU A 1 169 ? 162.132 139.486 177.068 1.00 152.67 ? 169 GLU A CG  1 
ATOM   1205 C  CD  . GLU A 1 169 ? 162.830 140.040 178.295 1.00 152.67 ? 169 GLU A CD  1 
ATOM   1206 O  OE1 . GLU A 1 169 ? 162.264 139.930 179.401 1.00 152.67 ? 169 GLU A OE1 1 
ATOM   1207 O  OE2 . GLU A 1 169 ? 163.947 140.582 178.153 1.00 152.67 ? 169 GLU A OE2 1 
ATOM   1208 N  N   . ALA A 1 170 ? 158.881 137.295 177.959 1.00 146.34 ? 170 ALA A N   1 
ATOM   1209 C  CA  . ALA A 1 170 ? 157.659 137.690 178.659 1.00 146.34 ? 170 ALA A CA  1 
ATOM   1210 C  C   . ALA A 1 170 ? 158.046 138.589 179.828 1.00 146.34 ? 170 ALA A C   1 
ATOM   1211 O  O   . ALA A 1 170 ? 158.451 138.110 180.892 1.00 146.34 ? 170 ALA A O   1 
ATOM   1212 C  CB  . ALA A 1 170 ? 156.883 136.464 179.126 1.00 146.34 ? 170 ALA A CB  1 
ATOM   1213 N  N   . VAL A 1 171 ? 157.913 139.897 179.634 1.00 146.88 ? 171 VAL A N   1 
ATOM   1214 C  CA  . VAL A 1 171 ? 158.308 140.875 180.642 1.00 146.88 ? 171 VAL A CA  1 
ATOM   1215 C  C   . VAL A 1 171 ? 157.182 141.044 181.654 1.00 146.88 ? 171 VAL A C   1 
ATOM   1216 O  O   . VAL A 1 171 ? 156.031 141.305 181.283 1.00 146.88 ? 171 VAL A O   1 
ATOM   1217 C  CB  . VAL A 1 171 ? 158.667 142.213 179.980 1.00 146.88 ? 171 VAL A CB  1 
ATOM   1218 C  CG1 . VAL A 1 171 ? 159.085 143.229 181.024 1.00 146.88 ? 171 VAL A CG1 1 
ATOM   1219 C  CG2 . VAL A 1 171 ? 159.768 142.015 178.948 1.00 146.88 ? 171 VAL A CG2 1 
ATOM   1220 N  N   . GLU A 1 172 ? 157.513 140.907 182.936 1.00 148.11 ? 172 GLU A N   1 
ATOM   1221 C  CA  . GLU A 1 172 ? 156.528 141.009 184.012 1.00 148.11 ? 172 GLU A CA  1 
ATOM   1222 C  C   . GLU A 1 172 ? 156.477 142.454 184.495 1.00 148.11 ? 172 GLU A C   1 
ATOM   1223 O  O   . GLU A 1 172 ? 157.377 142.915 185.200 1.00 148.11 ? 172 GLU A O   1 
ATOM   1224 C  CB  . GLU A 1 172 ? 156.875 140.060 185.153 1.00 148.11 ? 172 GLU A CB  1 
ATOM   1225 C  CG  . GLU A 1 172 ? 157.538 138.761 184.727 1.00 148.11 ? 172 GLU A CG  1 
ATOM   1226 C  CD  . GLU A 1 172 ? 156.577 137.815 184.026 1.00 148.11 ? 172 GLU A CD  1 
ATOM   1227 O  OE1 . GLU A 1 172 ? 155.353 137.922 184.248 1.00 148.11 ? 172 GLU A OE1 1 
ATOM   1228 O  OE2 . GLU A 1 172 ? 157.044 136.950 183.260 1.00 148.11 ? 172 GLU A OE2 1 
ATOM   1229 N  N   . LYS A 1 173 ? 155.417 143.169 184.118 1.00 148.62 ? 173 LYS A N   1 
ATOM   1230 C  CA  . LYS A 1 173 ? 155.181 144.514 184.635 1.00 148.62 ? 173 LYS A CA  1 
ATOM   1231 C  C   . LYS A 1 173 ? 154.869 144.486 186.128 1.00 148.62 ? 173 LYS A C   1 
ATOM   1232 O  O   . LYS A 1 173 ? 154.181 143.588 186.622 1.00 148.62 ? 173 LYS A O   1 
ATOM   1233 C  CB  . LYS A 1 173 ? 154.040 145.204 183.873 1.00 148.62 ? 173 LYS A CB  1 
ATOM   1234 C  CG  . LYS A 1 173 ? 154.186 145.417 182.356 1.00 148.62 ? 173 LYS A CG  1 
ATOM   1235 C  CD  . LYS A 1 173 ? 155.621 145.418 181.860 1.00 148.62 ? 173 LYS A CD  1 
ATOM   1236 C  CE  . LYS A 1 173 ? 155.714 144.941 180.439 1.00 148.62 ? 173 LYS A CE  1 
ATOM   1237 N  NZ  . LYS A 1 173 ? 155.640 143.469 180.409 1.00 148.62 ? 173 LYS A NZ  1 
ATOM   1238 N  N   . TYR A 1 174 ? 155.378 145.488 186.844 1.00 155.43 ? 174 TYR A N   1 
ATOM   1239 C  CA  . TYR A 1 174 ? 155.265 145.579 188.293 1.00 155.43 ? 174 TYR A CA  1 
ATOM   1240 C  C   . TYR A 1 174 ? 154.867 146.999 188.692 1.00 155.43 ? 174 TYR A C   1 
ATOM   1241 O  O   . TYR A 1 174 ? 154.554 147.848 187.851 1.00 155.43 ? 174 TYR A O   1 
ATOM   1242 C  CB  . TYR A 1 174 ? 156.582 145.183 188.975 1.00 155.43 ? 174 TYR A CB  1 
ATOM   1243 C  CG  . TYR A 1 174 ? 156.974 143.730 188.798 1.00 155.43 ? 174 TYR A CG  1 
ATOM   1244 C  CD1 . TYR A 1 174 ? 156.069 142.707 189.047 1.00 155.43 ? 174 TYR A CD1 1 
ATOM   1245 C  CD2 . TYR A 1 174 ? 158.257 143.382 188.385 1.00 155.43 ? 174 TYR A CD2 1 
ATOM   1246 C  CE1 . TYR A 1 174 ? 156.428 141.378 188.886 1.00 155.43 ? 174 TYR A CE1 1 
ATOM   1247 C  CE2 . TYR A 1 174 ? 158.626 142.056 188.222 1.00 155.43 ? 174 TYR A CE2 1 
ATOM   1248 C  CZ  . TYR A 1 174 ? 157.708 141.059 188.474 1.00 155.43 ? 174 TYR A CZ  1 
ATOM   1249 O  OH  . TYR A 1 174 ? 158.069 139.740 188.314 1.00 155.43 ? 174 TYR A OH  1 
ATOM   1250 N  N   . ILE A 1 175 ? 154.874 147.247 190.004 1.00 159.65 ? 175 ILE A N   1 
ATOM   1251 C  CA  . ILE A 1 175 ? 154.602 148.578 190.534 1.00 159.65 ? 175 ILE A CA  1 
ATOM   1252 C  C   . ILE A 1 175 ? 155.765 149.533 190.278 1.00 159.65 ? 175 ILE A C   1 
ATOM   1253 O  O   . ILE A 1 175 ? 155.563 150.753 190.223 1.00 159.65 ? 175 ILE A O   1 
ATOM   1254 C  CB  . ILE A 1 175 ? 154.272 148.458 192.039 1.00 159.65 ? 175 ILE A CB  1 
ATOM   1255 C  CG1 . ILE A 1 175 ? 153.869 149.803 192.656 1.00 159.65 ? 175 ILE A CG1 1 
ATOM   1256 C  CG2 . ILE A 1 175 ? 155.446 147.858 192.800 1.00 159.65 ? 175 ILE A CG2 1 
ATOM   1257 C  CD1 . ILE A 1 175 ? 152.763 150.527 191.925 1.00 159.65 ? 175 ILE A CD1 1 
ATOM   1258 N  N   . ASP A 1 176 ? 156.974 149.004 190.085 1.00 165.25 ? 176 ASP A N   1 
ATOM   1259 C  CA  . ASP A 1 176 ? 158.173 149.830 189.994 1.00 165.25 ? 176 ASP A CA  1 
ATOM   1260 C  C   . ASP A 1 176 ? 158.129 150.737 188.769 1.00 165.25 ? 176 ASP A C   1 
ATOM   1261 O  O   . ASP A 1 176 ? 157.775 150.302 187.669 1.00 165.25 ? 176 ASP A O   1 
ATOM   1262 C  CB  . ASP A 1 176 ? 159.415 148.941 189.946 1.00 165.25 ? 176 ASP A CB  1 
ATOM   1263 C  CG  . ASP A 1 176 ? 160.671 149.713 189.604 1.00 165.25 ? 176 ASP A CG  1 
ATOM   1264 O  OD1 . ASP A 1 176 ? 160.914 150.759 190.240 1.00 165.25 ? 176 ASP A OD1 1 
ATOM   1265 O  OD2 . ASP A 1 176 ? 161.415 149.273 188.701 1.00 165.25 ? 176 ASP A OD2 1 
ATOM   1266 N  N   . THR A 1 177 ? 158.482 152.004 188.969 1.00 160.36 ? 177 THR A N   1 
ATOM   1267 C  CA  . THR A 1 177 ? 158.534 152.991 187.904 1.00 160.36 ? 177 THR A CA  1 
ATOM   1268 C  C   . THR A 1 177 ? 159.981 153.204 187.462 1.00 160.36 ? 177 THR A C   1 
ATOM   1269 O  O   . THR A 1 177 ? 160.922 152.638 188.024 1.00 160.36 ? 177 THR A O   1 
ATOM   1270 C  CB  . THR A 1 177 ? 157.896 154.307 188.356 1.00 160.36 ? 177 THR A CB  1 
ATOM   1271 O  OG1 . THR A 1 177 ? 157.798 155.201 187.241 1.00 160.36 ? 177 THR A OG1 1 
ATOM   1272 C  CG2 . THR A 1 177 ? 158.731 154.960 189.449 1.00 160.36 ? 177 THR A CG2 1 
ATOM   1273 N  N   . ILE A 1 178 ? 160.158 154.032 186.436 1.00 158.51 ? 178 ILE A N   1 
ATOM   1274 C  CA  . ILE A 1 178 ? 161.481 154.294 185.872 1.00 158.51 ? 178 ILE A CA  1 
ATOM   1275 C  C   . ILE A 1 178 ? 161.755 155.793 185.908 1.00 158.51 ? 178 ILE A C   1 
ATOM   1276 O  O   . ILE A 1 178 ? 161.587 156.477 184.887 1.00 158.51 ? 178 ILE A O   1 
ATOM   1277 C  CB  . ILE A 1 178 ? 161.605 153.754 184.437 1.00 158.51 ? 178 ILE A CB  1 
ATOM   1278 C  CG1 . ILE A 1 178 ? 160.853 152.430 184.276 1.00 158.51 ? 178 ILE A CG1 1 
ATOM   1279 C  CG2 . ILE A 1 178 ? 163.069 153.581 184.060 1.00 158.51 ? 178 ILE A CG2 1 
ATOM   1280 C  CD1 . ILE A 1 178 ? 161.519 151.254 184.967 1.00 158.51 ? 178 ILE A CD1 1 
ATOM   1281 N  N   . PRO A 1 179 ? 162.176 156.344 187.047 1.00 151.64 ? 179 PRO A N   1 
ATOM   1282 C  CA  . PRO A 1 179 ? 162.431 157.790 187.117 1.00 151.64 ? 179 PRO A CA  1 
ATOM   1283 C  C   . PRO A 1 179 ? 163.703 158.171 186.372 1.00 151.64 ? 179 PRO A C   1 
ATOM   1284 O  O   . PRO A 1 179 ? 164.724 157.486 186.468 1.00 151.64 ? 179 PRO A O   1 
ATOM   1285 C  CB  . PRO A 1 179 ? 162.556 158.055 188.622 1.00 151.64 ? 179 PRO A CB  1 
ATOM   1286 C  CG  . PRO A 1 179 ? 163.016 156.756 189.190 1.00 151.64 ? 179 PRO A CG  1 
ATOM   1287 C  CD  . PRO A 1 179 ? 162.405 155.674 188.339 1.00 151.64 ? 179 PRO A CD  1 
ATOM   1288 N  N   . ASP A 1 180 ? 163.619 159.273 185.620 1.00 147.13 ? 180 ASP A N   1 
ATOM   1289 C  CA  . ASP A 1 180 ? 164.755 159.870 184.908 1.00 147.13 ? 180 ASP A CA  1 
ATOM   1290 C  C   . ASP A 1 180 ? 165.384 158.901 183.908 1.00 147.13 ? 180 ASP A C   1 
ATOM   1291 O  O   . ASP A 1 180 ? 166.593 158.927 183.671 1.00 147.13 ? 180 ASP A O   1 
ATOM   1292 C  CB  . ASP A 1 180 ? 165.807 160.399 185.888 1.00 147.13 ? 180 ASP A CB  1 
ATOM   1293 C  CG  . ASP A 1 180 ? 165.310 161.583 186.692 1.00 147.13 ? 180 ASP A CG  1 
ATOM   1294 O  OD1 . ASP A 1 180 ? 164.265 162.157 186.321 1.00 147.13 ? 180 ASP A OD1 1 
ATOM   1295 O  OD2 . ASP A 1 180 ? 165.964 161.941 187.694 1.00 147.13 ? 180 ASP A OD2 1 
ATOM   1296 N  N   . GLU A 1 181 ? 164.557 158.046 183.308 1.00 155.04 ? 181 GLU A N   1 
ATOM   1297 C  CA  . GLU A 1 181 ? 165.029 157.114 182.294 1.00 155.04 ? 181 GLU A CA  1 
ATOM   1298 C  C   . GLU A 1 181 ? 163.855 156.681 181.428 1.00 155.04 ? 181 GLU A C   1 
ATOM   1299 O  O   . GLU A 1 181 ? 162.746 156.486 181.930 1.00 155.04 ? 181 GLU A O   1 
ATOM   1300 C  CB  . GLU A 1 181 ? 165.704 155.888 182.922 1.00 155.04 ? 181 GLU A CB  1 
ATOM   1301 C  CG  . GLU A 1 181 ? 167.214 155.843 182.741 1.00 155.04 ? 181 GLU A CG  1 
ATOM   1302 C  CD  . GLU A 1 181 ? 167.630 155.589 181.302 1.00 155.04 ? 181 GLU A CD  1 
ATOM   1303 O  OE1 . GLU A 1 181 ? 166.817 155.038 180.529 1.00 155.04 ? 181 GLU A OE1 1 
ATOM   1304 O  OE2 . GLU A 1 181 ? 168.772 155.944 180.943 1.00 155.04 ? 181 GLU A OE2 1 
ATOM   1305 N  N   . VAL A 1 182 ? 164.112 156.537 180.129 1.00 157.18 ? 182 VAL A N   1 
ATOM   1306 C  CA  . VAL A 1 182 ? 163.113 156.103 179.160 1.00 157.18 ? 182 VAL A CA  1 
ATOM   1307 C  C   . VAL A 1 182 ? 163.720 154.993 178.313 1.00 157.18 ? 182 VAL A C   1 
ATOM   1308 O  O   . VAL A 1 182 ? 164.804 155.165 177.744 1.00 157.18 ? 182 VAL A O   1 
ATOM   1309 C  CB  . VAL A 1 182 ? 162.636 157.270 178.271 1.00 157.18 ? 182 VAL A CB  1 
ATOM   1310 C  CG1 . VAL A 1 182 ? 161.943 156.752 177.017 1.00 157.18 ? 182 VAL A CG1 1 
ATOM   1311 C  CG2 . VAL A 1 182 ? 161.712 158.192 179.053 1.00 157.18 ? 182 VAL A CG2 1 
ATOM   1312 N  N   . GLY A 1 183 ? 163.027 153.859 178.232 1.00 153.27 ? 183 GLY A N   1 
ATOM   1313 C  CA  . GLY A 1 183 ? 163.492 152.746 177.428 1.00 153.27 ? 183 GLY A CA  1 
ATOM   1314 C  C   . GLY A 1 183 ? 162.392 151.765 177.076 1.00 153.27 ? 183 GLY A C   1 
ATOM   1315 O  O   . GLY A 1 183 ? 161.638 151.330 177.951 1.00 153.27 ? 183 GLY A O   1 
ATOM   1316 N  N   . LEU A 1 184 ? 162.299 151.397 175.801 1.00 151.82 ? 184 LEU A N   1 
ATOM   1317 C  CA  . LEU A 1 184 ? 161.243 150.516 175.318 1.00 151.82 ? 184 LEU A CA  1 
ATOM   1318 C  C   . LEU A 1 184 ? 161.571 149.038 175.490 1.00 151.82 ? 184 LEU A C   1 
ATOM   1319 O  O   . LEU A 1 184 ? 160.759 148.191 175.103 1.00 151.82 ? 184 LEU A O   1 
ATOM   1320 C  CB  . LEU A 1 184 ? 160.947 150.805 173.842 1.00 151.82 ? 184 LEU A CB  1 
ATOM   1321 C  CG  . LEU A 1 184 ? 159.718 151.667 173.547 1.00 151.82 ? 184 LEU A CG  1 
ATOM   1322 C  CD1 . LEU A 1 184 ? 159.960 153.111 173.955 1.00 151.82 ? 184 LEU A CD1 1 
ATOM   1323 C  CD2 . LEU A 1 184 ? 159.342 151.577 172.076 1.00 151.82 ? 184 LEU A CD2 1 
ATOM   1324 N  N   . GLY A 1 185 ? 162.727 148.710 176.060 1.00 157.94 ? 185 GLY A N   1 
ATOM   1325 C  CA  . GLY A 1 185 ? 163.120 147.326 176.236 1.00 157.94 ? 185 GLY A CA  1 
ATOM   1326 C  C   . GLY A 1 185 ? 162.508 146.684 177.463 1.00 157.94 ? 185 GLY A C   1 
ATOM   1327 O  O   . GLY A 1 185 ? 161.293 146.765 177.674 1.00 157.94 ? 185 GLY A O   1 
ATOM   1328 N  N   . ASP A 1 186 ? 163.340 146.040 178.280 1.00 156.70 ? 186 ASP A N   1 
ATOM   1329 C  CA  . ASP A 1 186 ? 162.862 145.359 179.476 1.00 156.70 ? 186 ASP A CA  1 
ATOM   1330 C  C   . ASP A 1 186 ? 162.470 146.374 180.542 1.00 156.70 ? 186 ASP A C   1 
ATOM   1331 O  O   . ASP A 1 186 ? 163.315 146.829 181.320 1.00 156.70 ? 186 ASP A O   1 
ATOM   1332 C  CB  . ASP A 1 186 ? 163.933 144.403 180.009 1.00 156.70 ? 186 ASP A CB  1 
ATOM   1333 C  CG  . ASP A 1 186 ? 163.348 143.255 180.813 1.00 156.70 ? 186 ASP A CG  1 
ATOM   1334 O  OD1 . ASP A 1 186 ? 162.366 143.478 181.552 1.00 156.70 ? 186 ASP A OD1 1 
ATOM   1335 O  OD2 . ASP A 1 186 ? 163.873 142.127 180.705 1.00 156.70 ? 186 ASP A OD2 1 
ATOM   1336 N  N   . ARG A 1 187 ? 161.189 146.732 180.582 1.00 153.96 ? 187 ARG A N   1 
ATOM   1337 C  CA  . ARG A 1 187 ? 160.666 147.700 181.534 1.00 153.96 ? 187 ARG A CA  1 
ATOM   1338 C  C   . ARG A 1 187 ? 159.355 147.191 182.110 1.00 153.96 ? 187 ARG A C   1 
ATOM   1339 O  O   . ARG A 1 187 ? 158.629 146.441 181.452 1.00 153.96 ? 187 ARG A O   1 
ATOM   1340 C  CB  . ARG A 1 187 ? 160.459 149.069 180.883 1.00 153.96 ? 187 ARG A CB  1 
ATOM   1341 C  CG  . ARG A 1 187 ? 161.384 150.139 181.430 1.00 153.96 ? 187 ARG A CG  1 
ATOM   1342 C  CD  . ARG A 1 187 ? 162.757 150.072 180.786 1.00 153.96 ? 187 ARG A CD  1 
ATOM   1343 N  NE  . ARG A 1 187 ? 163.408 151.376 180.765 1.00 153.96 ? 187 ARG A NE  1 
ATOM   1344 C  CZ  . ARG A 1 187 ? 164.711 151.563 180.602 1.00 153.96 ? 187 ARG A CZ  1 
ATOM   1345 N  NH1 . ARG A 1 187 ? 165.540 150.546 180.437 1.00 153.96 ? 187 ARG A NH1 1 
ATOM   1346 N  NH2 . ARG A 1 187 ? 165.193 152.802 180.605 1.00 153.96 ? 187 ARG A NH2 1 
ATOM   1347 N  N   . VAL A 1 188 ? 159.057 147.606 183.341 1.00 152.50 ? 188 VAL A N   1 
ATOM   1348 C  CA  . VAL A 1 188 ? 157.903 147.117 184.083 1.00 152.50 ? 188 VAL A CA  1 
ATOM   1349 C  C   . VAL A 1 188 ? 156.890 148.211 184.393 1.00 152.50 ? 188 VAL A C   1 
ATOM   1350 O  O   . VAL A 1 188 ? 155.837 147.914 184.968 1.00 152.50 ? 188 VAL A O   1 
ATOM   1351 C  CB  . VAL A 1 188 ? 158.341 146.413 185.384 1.00 152.50 ? 188 VAL A CB  1 
ATOM   1352 C  CG1 . VAL A 1 188 ? 159.454 145.420 185.100 1.00 152.50 ? 188 VAL A CG1 1 
ATOM   1353 C  CG2 . VAL A 1 188 ? 158.791 147.432 186.415 1.00 152.50 ? 188 VAL A CG2 1 
ATOM   1354 N  N   . ASN A 1 189 ? 157.166 149.464 184.017 1.00 150.77 ? 189 ASN A N   1 
ATOM   1355 C  CA  . ASN A 1 189 ? 156.365 150.583 184.509 1.00 150.77 ? 189 ASN A CA  1 
ATOM   1356 C  C   . ASN A 1 189 ? 154.998 150.648 183.828 1.00 150.77 ? 189 ASN A C   1 
ATOM   1357 O  O   . ASN A 1 189 ? 153.980 150.881 184.490 1.00 150.77 ? 189 ASN A O   1 
ATOM   1358 C  CB  . ASN A 1 189 ? 157.145 151.889 184.334 1.00 150.77 ? 189 ASN A CB  1 
ATOM   1359 C  CG  . ASN A 1 189 ? 156.449 153.078 184.969 1.00 150.77 ? 189 ASN A CG  1 
ATOM   1360 O  OD1 . ASN A 1 189 ? 155.782 152.944 185.995 1.00 150.77 ? 189 ASN A OD1 1 
ATOM   1361 N  ND2 . ASN A 1 189 ? 156.619 154.255 184.371 1.00 150.77 ? 189 ASN A ND2 1 
ATOM   1362 N  N   . MET A 1 190 ? 154.947 150.441 182.509 1.00 146.30 ? 190 MET A N   1 
ATOM   1363 C  CA  . MET A 1 190 ? 153.685 150.427 181.778 1.00 146.30 ? 190 MET A CA  1 
ATOM   1364 C  C   . MET A 1 190 ? 153.500 149.128 181.005 1.00 146.30 ? 190 MET A C   1 
ATOM   1365 O  O   . MET A 1 190 ? 154.464 148.434 180.666 1.00 146.30 ? 190 MET A O   1 
ATOM   1366 C  CB  . MET A 1 190 ? 153.532 151.569 180.749 1.00 146.30 ? 190 MET A CB  1 
ATOM   1367 C  CG  . MET A 1 190 ? 153.683 152.993 181.226 1.00 146.30 ? 190 MET A CG  1 
ATOM   1368 S  SD  . MET A 1 190 ? 155.331 153.405 181.789 1.00 146.30 ? 190 MET A SD  1 
ATOM   1369 C  CE  . MET A 1 190 ? 155.851 154.446 180.433 1.00 146.30 ? 190 MET A CE  1 
ATOM   1370 N  N   . VAL A 1 191 ? 152.237 148.836 180.707 1.00 149.63 ? 191 VAL A N   1 
ATOM   1371 C  CA  . VAL A 1 191 ? 151.865 147.776 179.778 1.00 149.63 ? 191 VAL A CA  1 
ATOM   1372 C  C   . VAL A 1 191 ? 151.587 148.435 178.430 1.00 149.63 ? 191 VAL A C   1 
ATOM   1373 O  O   . VAL A 1 191 ? 150.511 149.001 178.218 1.00 149.63 ? 191 VAL A O   1 
ATOM   1374 C  CB  . VAL A 1 191 ? 150.640 147.000 180.273 1.00 149.63 ? 191 VAL A CB  1 
ATOM   1375 C  CG1 . VAL A 1 191 ? 150.415 145.762 179.418 1.00 149.63 ? 191 VAL A CG1 1 
ATOM   1376 C  CG2 . VAL A 1 191 ? 150.771 146.650 181.748 1.00 149.63 ? 191 VAL A CG2 1 
ATOM   1377 N  N   . PHE A 1 192 ? 152.551 148.357 177.518 1.00 147.55 ? 192 PHE A N   1 
ATOM   1378 C  CA  . PHE A 1 192 ? 152.473 149.074 176.256 1.00 147.55 ? 192 PHE A CA  1 
ATOM   1379 C  C   . PHE A 1 192 ? 151.450 148.436 175.318 1.00 147.55 ? 192 PHE A C   1 
ATOM   1380 O  O   . PHE A 1 192 ? 151.029 147.289 175.490 1.00 147.55 ? 192 PHE A O   1 
ATOM   1381 C  CB  . PHE A 1 192 ? 153.839 149.123 175.574 1.00 147.55 ? 192 PHE A CB  1 
ATOM   1382 C  CG  . PHE A 1 192 ? 154.978 149.428 176.505 1.00 147.55 ? 192 PHE A CG  1 
ATOM   1383 C  CD1 . PHE A 1 192 ? 155.286 150.738 176.836 1.00 147.55 ? 192 PHE A CD1 1 
ATOM   1384 C  CD2 . PHE A 1 192 ? 155.750 148.408 177.039 1.00 147.55 ? 192 PHE A CD2 1 
ATOM   1385 C  CE1 . PHE A 1 192 ? 156.340 151.025 177.683 1.00 147.55 ? 192 PHE A CE1 1 
ATOM   1386 C  CE2 . PHE A 1 192 ? 156.802 148.688 177.889 1.00 147.55 ? 192 PHE A CE2 1 
ATOM   1387 C  CZ  . PHE A 1 192 ? 157.097 149.997 178.211 1.00 147.55 ? 192 PHE A CZ  1 
ATOM   1388 N  N   . SER A 1 193 ? 151.059 149.204 174.304 1.00 136.32 ? 193 SER A N   1 
ATOM   1389 C  CA  . SER A 1 193 ? 150.094 148.756 173.315 1.00 136.32 ? 193 SER A CA  1 
ATOM   1390 C  C   . SER A 1 193 ? 150.725 147.746 172.363 1.00 136.32 ? 193 SER A C   1 
ATOM   1391 O  O   . SER A 1 193 ? 151.949 147.620 172.266 1.00 136.32 ? 193 SER A O   1 
ATOM   1392 C  CB  . SER A 1 193 ? 149.546 149.941 172.522 1.00 136.32 ? 193 SER A CB  1 
ATOM   1393 O  OG  . SER A 1 193 ? 148.685 149.502 171.486 1.00 136.32 ? 193 SER A OG  1 
ATOM   1394 N  N   . GLY A 1 194 ? 149.865 147.021 171.651 1.00 129.76 ? 194 GLY A N   1 
ATOM   1395 C  CA  . GLY A 1 194 ? 150.338 146.006 170.733 1.00 129.76 ? 194 GLY A CA  1 
ATOM   1396 C  C   . GLY A 1 194 ? 150.928 144.788 171.401 1.00 129.76 ? 194 GLY A C   1 
ATOM   1397 O  O   . GLY A 1 194 ? 151.709 144.066 170.777 1.00 129.76 ? 194 GLY A O   1 
ATOM   1398 N  N   . SER A 1 195 ? 150.576 144.539 172.659 1.00 129.94 ? 195 SER A N   1 
ATOM   1399 C  CA  . SER A 1 195 ? 151.156 143.464 173.446 1.00 129.94 ? 195 SER A CA  1 
ATOM   1400 C  C   . SER A 1 195 ? 150.079 142.465 173.844 1.00 129.94 ? 195 SER A C   1 
ATOM   1401 O  O   . SER A 1 195 ? 148.910 142.821 174.015 1.00 129.94 ? 195 SER A O   1 
ATOM   1402 C  CB  . SER A 1 195 ? 151.850 144.014 174.694 1.00 129.94 ? 195 SER A CB  1 
ATOM   1403 O  OG  . SER A 1 195 ? 153.083 144.627 174.361 1.00 129.94 ? 195 SER A OG  1 
ATOM   1404 N  N   . LEU A 1 196 ? 150.486 141.210 173.994 1.00 126.27 ? 196 LEU A N   1 
ATOM   1405 C  CA  . LEU A 1 196 ? 149.579 140.111 174.296 1.00 126.27 ? 196 LEU A CA  1 
ATOM   1406 C  C   . LEU A 1 196 ? 149.790 139.651 175.731 1.00 126.27 ? 196 LEU A C   1 
ATOM   1407 O  O   . LEU A 1 196 ? 150.930 139.442 176.159 1.00 126.27 ? 196 LEU A O   1 
ATOM   1408 C  CB  . LEU A 1 196 ? 149.800 138.948 173.329 1.00 126.27 ? 196 LEU A CB  1 
ATOM   1409 C  CG  . LEU A 1 196 ? 149.776 139.281 171.836 1.00 126.27 ? 196 LEU A CG  1 
ATOM   1410 C  CD1 . LEU A 1 196 ? 149.920 138.014 171.009 1.00 126.27 ? 196 LEU A CD1 1 
ATOM   1411 C  CD2 . LEU A 1 196 ? 148.500 140.023 171.468 1.00 126.27 ? 196 LEU A CD2 1 
ATOM   1412 N  N   . VAL A 1 197 ? 148.693 139.495 176.470 1.00 128.28 ? 197 VAL A N   1 
ATOM   1413 C  CA  . VAL A 1 197 ? 148.747 139.037 177.858 1.00 128.28 ? 197 VAL A CA  1 
ATOM   1414 C  C   . VAL A 1 197 ? 148.872 137.516 177.835 1.00 128.28 ? 197 VAL A C   1 
ATOM   1415 O  O   . VAL A 1 197 ? 147.876 136.805 177.698 1.00 128.28 ? 197 VAL A O   1 
ATOM   1416 C  CB  . VAL A 1 197 ? 147.527 139.490 178.662 1.00 128.28 ? 197 VAL A CB  1 
ATOM   1417 C  CG1 . VAL A 1 197 ? 147.657 139.048 180.112 1.00 128.28 ? 197 VAL A CG1 1 
ATOM   1418 C  CG2 . VAL A 1 197 ? 147.364 140.996 178.579 1.00 128.28 ? 197 VAL A CG2 1 
ATOM   1419 N  N   . VAL A 1 198 ? 150.101 137.012 177.967 1.00 132.02 ? 198 VAL A N   1 
ATOM   1420 C  CA  . VAL A 1 198 ? 150.313 135.568 178.013 1.00 132.02 ? 198 VAL A CA  1 
ATOM   1421 C  C   . VAL A 1 198 ? 149.783 134.990 179.319 1.00 132.02 ? 198 VAL A C   1 
ATOM   1422 O  O   . VAL A 1 198 ? 149.176 133.913 179.336 1.00 132.02 ? 198 VAL A O   1 
ATOM   1423 C  CB  . VAL A 1 198 ? 151.803 135.239 177.809 1.00 132.02 ? 198 VAL A CB  1 
ATOM   1424 C  CG1 . VAL A 1 198 ? 151.968 133.807 177.323 1.00 132.02 ? 198 VAL A CG1 1 
ATOM   1425 C  CG2 . VAL A 1 198 ? 152.433 136.217 176.829 1.00 132.02 ? 198 VAL A CG2 1 
ATOM   1426 N  N   . TYR A 1 199 ? 150.011 135.685 180.431 1.00 135.58 ? 199 TYR A N   1 
ATOM   1427 C  CA  . TYR A 1 199 ? 149.493 135.265 181.725 1.00 135.58 ? 199 TYR A CA  1 
ATOM   1428 C  C   . TYR A 1 199 ? 149.468 136.478 182.642 1.00 135.58 ? 199 TYR A C   1 
ATOM   1429 O  O   . TYR A 1 199 ? 150.208 137.443 182.440 1.00 135.58 ? 199 TYR A O   1 
ATOM   1430 C  CB  . TYR A 1 199 ? 150.338 134.135 182.331 1.00 135.58 ? 199 TYR A CB  1 
ATOM   1431 C  CG  . TYR A 1 199 ? 149.755 133.531 183.590 1.00 135.58 ? 199 TYR A CG  1 
ATOM   1432 C  CD1 . TYR A 1 199 ? 148.504 132.928 183.578 1.00 135.58 ? 199 TYR A CD1 1 
ATOM   1433 C  CD2 . TYR A 1 199 ? 150.456 133.565 184.788 1.00 135.58 ? 199 TYR A CD2 1 
ATOM   1434 C  CE1 . TYR A 1 199 ? 147.967 132.375 184.726 1.00 135.58 ? 199 TYR A CE1 1 
ATOM   1435 C  CE2 . TYR A 1 199 ? 149.927 133.014 185.941 1.00 135.58 ? 199 TYR A CE2 1 
ATOM   1436 C  CZ  . TYR A 1 199 ? 148.683 132.422 185.904 1.00 135.58 ? 199 TYR A CZ  1 
ATOM   1437 O  OH  . TYR A 1 199 ? 148.154 131.873 187.049 1.00 135.58 ? 199 TYR A OH  1 
ATOM   1438 N  N   . GLY A 1 200 ? 148.599 136.423 183.643 1.00 139.69 ? 200 GLY A N   1 
ATOM   1439 C  CA  . GLY A 1 200 ? 148.523 137.453 184.660 1.00 139.69 ? 200 GLY A CA  1 
ATOM   1440 C  C   . GLY A 1 200 ? 147.205 138.209 184.614 1.00 139.69 ? 200 GLY A C   1 
ATOM   1441 O  O   . GLY A 1 200 ? 146.326 137.952 183.791 1.00 139.69 ? 200 GLY A O   1 
ATOM   1442 N  N   . ARG A 1 201 ? 147.093 139.164 185.536 1.00 145.98 ? 201 ARG A N   1 
ATOM   1443 C  CA  . ARG A 1 201 ? 145.908 140.002 185.689 1.00 145.98 ? 201 ARG A CA  1 
ATOM   1444 C  C   . ARG A 1 201 ? 146.327 141.454 185.489 1.00 145.98 ? 201 ARG A C   1 
ATOM   1445 O  O   . ARG A 1 201 ? 146.956 142.051 186.370 1.00 145.98 ? 201 ARG A O   1 
ATOM   1446 C  CB  . ARG A 1 201 ? 145.260 139.768 187.057 1.00 145.98 ? 201 ARG A CB  1 
ATOM   1447 C  CG  . ARG A 1 201 ? 143.957 140.516 187.308 1.00 145.98 ? 201 ARG A CG  1 
ATOM   1448 C  CD  . ARG A 1 201 ? 144.177 141.772 188.138 1.00 145.98 ? 201 ARG A CD  1 
ATOM   1449 N  NE  . ARG A 1 201 ? 144.762 141.453 189.435 1.00 145.98 ? 201 ARG A NE  1 
ATOM   1450 C  CZ  . ARG A 1 201 ? 145.699 142.174 190.036 1.00 145.98 ? 201 ARG A CZ  1 
ATOM   1451 N  NH1 . ARG A 1 201 ? 146.187 143.272 189.485 1.00 145.98 ? 201 ARG A NH1 1 
ATOM   1452 N  NH2 . ARG A 1 201 ? 146.156 141.782 191.222 1.00 145.98 ? 201 ARG A NH2 1 
ATOM   1453 N  N   . GLY A 1 202 ? 145.976 142.017 184.335 1.00 149.60 ? 202 GLY A N   1 
ATOM   1454 C  CA  . GLY A 1 202 ? 146.419 143.345 183.955 1.00 149.60 ? 202 GLY A CA  1 
ATOM   1455 C  C   . GLY A 1 202 ? 145.531 144.476 184.430 1.00 149.60 ? 202 GLY A C   1 
ATOM   1456 O  O   . GLY A 1 202 ? 144.795 145.071 183.637 1.00 149.60 ? 202 GLY A O   1 
ATOM   1457 N  N   . MET A 1 203 ? 145.592 144.785 185.723 1.00 153.21 ? 203 MET A N   1 
ATOM   1458 C  CA  . MET A 1 203 ? 144.822 145.883 186.307 1.00 153.21 ? 203 MET A CA  1 
ATOM   1459 C  C   . MET A 1 203 ? 145.647 147.155 186.152 1.00 153.21 ? 203 MET A C   1 
ATOM   1460 O  O   . MET A 1 203 ? 146.493 147.477 186.987 1.00 153.21 ? 203 MET A O   1 
ATOM   1461 C  CB  . MET A 1 203 ? 144.500 145.587 187.766 1.00 153.21 ? 203 MET A CB  1 
ATOM   1462 C  CG  . MET A 1 203 ? 143.280 146.301 188.324 1.00 153.21 ? 203 MET A CG  1 
ATOM   1463 S  SD  . MET A 1 203 ? 141.772 145.982 187.394 1.00 153.21 ? 203 MET A SD  1 
ATOM   1464 C  CE  . MET A 1 203 ? 140.727 147.305 187.992 1.00 153.21 ? 203 MET A CE  1 
ATOM   1465 N  N   . PHE A 1 204 ? 145.405 147.889 185.066 1.00 149.49 ? 204 PHE A N   1 
ATOM   1466 C  CA  . PHE A 1 204 ? 146.183 149.076 184.739 1.00 149.49 ? 204 PHE A CA  1 
ATOM   1467 C  C   . PHE A 1 204 ? 145.262 150.192 184.260 1.00 149.49 ? 204 PHE A C   1 
ATOM   1468 O  O   . PHE A 1 204 ? 144.064 149.995 184.044 1.00 149.49 ? 204 PHE A O   1 
ATOM   1469 C  CB  . PHE A 1 204 ? 147.250 148.763 183.677 1.00 149.49 ? 204 PHE A CB  1 
ATOM   1470 C  CG  . PHE A 1 204 ? 146.774 148.933 182.261 1.00 149.49 ? 204 PHE A CG  1 
ATOM   1471 C  CD1 . PHE A 1 204 ? 145.883 148.033 181.702 1.00 149.49 ? 204 PHE A CD1 1 
ATOM   1472 C  CD2 . PHE A 1 204 ? 147.232 149.985 181.484 1.00 149.49 ? 204 PHE A CD2 1 
ATOM   1473 C  CE1 . PHE A 1 204 ? 145.449 148.188 180.400 1.00 149.49 ? 204 PHE A CE1 1 
ATOM   1474 C  CE2 . PHE A 1 204 ? 146.799 150.141 180.181 1.00 149.49 ? 204 PHE A CE2 1 
ATOM   1475 C  CZ  . PHE A 1 204 ? 145.908 149.240 179.641 1.00 149.49 ? 204 PHE A CZ  1 
ATOM   1476 N  N   . VAL A 1 205 ? 145.843 151.379 184.097 1.00 151.03 ? 205 VAL A N   1 
ATOM   1477 C  CA  . VAL A 1 205 ? 145.135 152.564 183.625 1.00 151.03 ? 205 VAL A CA  1 
ATOM   1478 C  C   . VAL A 1 205 ? 145.788 153.025 182.331 1.00 151.03 ? 205 VAL A C   1 
ATOM   1479 O  O   . VAL A 1 205 ? 147.009 153.207 182.284 1.00 151.03 ? 205 VAL A O   1 
ATOM   1480 C  CB  . VAL A 1 205 ? 145.156 153.694 184.671 1.00 151.03 ? 205 VAL A CB  1 
ATOM   1481 C  CG1 . VAL A 1 205 ? 144.497 154.947 184.118 1.00 151.03 ? 205 VAL A CG1 1 
ATOM   1482 C  CG2 . VAL A 1 205 ? 144.476 153.248 185.947 1.00 151.03 ? 205 VAL A CG2 1 
ATOM   1483 N  N   . VAL A 1 206 ? 144.977 153.222 181.290 1.00 148.80 ? 206 VAL A N   1 
ATOM   1484 C  CA  . VAL A 1 206 ? 145.494 153.680 180.004 1.00 148.80 ? 206 VAL A CA  1 
ATOM   1485 C  C   . VAL A 1 206 ? 146.010 155.106 180.140 1.00 148.80 ? 206 VAL A C   1 
ATOM   1486 O  O   . VAL A 1 206 ? 145.309 155.992 180.646 1.00 148.80 ? 206 VAL A O   1 
ATOM   1487 C  CB  . VAL A 1 206 ? 144.409 153.582 178.920 1.00 148.80 ? 206 VAL A CB  1 
ATOM   1488 C  CG1 . VAL A 1 206 ? 144.803 154.385 177.689 1.00 148.80 ? 206 VAL A CG1 1 
ATOM   1489 C  CG2 . VAL A 1 206 ? 144.170 152.136 178.540 1.00 148.80 ? 206 VAL A CG2 1 
ATOM   1490 N  N   . THR A 1 207 ? 147.248 155.330 179.698 1.00 145.33 ? 207 THR A N   1 
ATOM   1491 C  CA  . THR A 1 207 ? 147.855 156.652 179.721 1.00 145.33 ? 207 THR A CA  1 
ATOM   1492 C  C   . THR A 1 207 ? 148.159 157.200 178.335 1.00 145.33 ? 207 THR A C   1 
ATOM   1493 O  O   . THR A 1 207 ? 148.689 158.313 178.230 1.00 145.33 ? 207 THR A O   1 
ATOM   1494 C  CB  . THR A 1 207 ? 149.152 156.635 180.545 1.00 145.33 ? 207 THR A CB  1 
ATOM   1495 O  OG1 . THR A 1 207 ? 150.116 155.786 179.910 1.00 145.33 ? 207 THR A OG1 1 
ATOM   1496 C  CG2 . THR A 1 207 ? 148.884 156.129 181.955 1.00 145.33 ? 207 THR A CG2 1 
ATOM   1497 N  N   . GLY A 1 208 ? 147.845 156.464 177.271 1.00 139.83 ? 208 GLY A N   1 
ATOM   1498 C  CA  . GLY A 1 208 ? 148.260 156.887 175.949 1.00 139.83 ? 208 GLY A CA  1 
ATOM   1499 C  C   . GLY A 1 208 ? 147.230 156.781 174.844 1.00 139.83 ? 208 GLY A C   1 
ATOM   1500 O  O   . GLY A 1 208 ? 146.575 155.748 174.677 1.00 139.83 ? 208 GLY A O   1 
ATOM   1501 N  N   . THR A 1 209 ? 147.082 157.864 174.085 1.00 140.41 ? 209 THR A N   1 
ATOM   1502 C  CA  . THR A 1 209 ? 146.356 157.829 172.825 1.00 140.41 ? 209 THR A CA  1 
ATOM   1503 C  C   . THR A 1 209 ? 147.102 156.940 171.833 1.00 140.41 ? 209 THR A C   1 
ATOM   1504 O  O   . THR A 1 209 ? 148.331 156.838 171.869 1.00 140.41 ? 209 THR A O   1 
ATOM   1505 C  CB  . THR A 1 209 ? 146.205 159.252 172.271 1.00 140.41 ? 209 THR A CB  1 
ATOM   1506 O  OG1 . THR A 1 209 ? 145.718 160.116 173.305 1.00 140.41 ? 209 THR A OG1 1 
ATOM   1507 C  CG2 . THR A 1 209 ? 145.235 159.301 171.097 1.00 140.41 ? 209 THR A CG2 1 
ATOM   1508 N  N   . ALA A 1 210 ? 146.345 156.276 170.950 1.00 136.79 ? 210 ALA A N   1 
ATOM   1509 C  CA  . ALA A 1 210 ? 146.952 155.371 169.975 1.00 136.79 ? 210 ALA A CA  1 
ATOM   1510 C  C   . ALA A 1 210 ? 147.925 156.094 169.051 1.00 136.79 ? 210 ALA A C   1 
ATOM   1511 O  O   . ALA A 1 210 ? 148.850 155.471 168.517 1.00 136.79 ? 210 ALA A O   1 
ATOM   1512 C  CB  . ALA A 1 210 ? 145.872 154.667 169.156 1.00 136.79 ? 210 ALA A CB  1 
ATOM   1513 N  N   . SER A 1 211 ? 147.729 157.398 168.842 1.00 136.42 ? 211 SER A N   1 
ATOM   1514 C  CA  . SER A 1 211 ? 148.732 158.190 168.139 1.00 136.42 ? 211 SER A CA  1 
ATOM   1515 C  C   . SER A 1 211 ? 150.029 158.269 168.937 1.00 136.42 ? 211 SER A C   1 
ATOM   1516 O  O   . SER A 1 211 ? 151.122 158.188 168.365 1.00 136.42 ? 211 SER A O   1 
ATOM   1517 C  CB  . SER A 1 211 ? 148.190 159.590 167.853 1.00 136.42 ? 211 SER A CB  1 
ATOM   1518 O  OG  . SER A 1 211 ? 147.744 160.217 169.043 1.00 136.42 ? 211 SER A OG  1 
ATOM   1519 N  N   . GLU A 1 212 ? 149.928 158.424 170.257 1.00 138.73 ? 212 GLU A N   1 
ATOM   1520 C  CA  . GLU A 1 212 ? 151.100 158.542 171.114 1.00 138.73 ? 212 GLU A CA  1 
ATOM   1521 C  C   . GLU A 1 212 ? 151.585 157.206 171.666 1.00 138.73 ? 212 GLU A C   1 
ATOM   1522 O  O   . GLU A 1 212 ? 152.627 157.175 172.332 1.00 138.73 ? 212 GLU A O   1 
ATOM   1523 C  CB  . GLU A 1 212 ? 150.813 159.519 172.266 1.00 138.73 ? 212 GLU A CB  1 
ATOM   1524 C  CG  . GLU A 1 212 ? 150.229 158.894 173.524 1.00 138.73 ? 212 GLU A CG  1 
ATOM   1525 C  CD  . GLU A 1 212 ? 150.078 159.894 174.654 1.00 138.73 ? 212 GLU A CD  1 
ATOM   1526 O  OE1 . GLU A 1 212 ? 151.076 160.563 174.994 1.00 138.73 ? 212 GLU A OE1 1 
ATOM   1527 O  OE2 . GLU A 1 212 ? 148.961 160.015 175.200 1.00 138.73 ? 212 GLU A OE2 1 
ATOM   1528 N  N   . THR A 1 213 ? 150.872 156.109 171.405 1.00 133.86 ? 213 THR A N   1 
ATOM   1529 C  CA  . THR A 1 213 ? 151.383 154.790 171.758 1.00 133.86 ? 213 THR A CA  1 
ATOM   1530 C  C   . THR A 1 213 ? 152.655 154.501 170.974 1.00 133.86 ? 213 THR A C   1 
ATOM   1531 O  O   . THR A 1 213 ? 152.797 154.919 169.822 1.00 133.86 ? 213 THR A O   1 
ATOM   1532 C  CB  . THR A 1 213 ? 150.345 153.702 171.471 1.00 133.86 ? 213 THR A CB  1 
ATOM   1533 O  OG1 . THR A 1 213 ? 149.849 153.847 170.135 1.00 133.86 ? 213 THR A OG1 1 
ATOM   1534 C  CG2 . THR A 1 213 ? 149.191 153.771 172.460 1.00 133.86 ? 213 THR A CG2 1 
ATOM   1535 N  N   . GLU A 1 214 ? 153.587 153.790 171.613 1.00 131.44 ? 214 GLU A N   1 
ATOM   1536 C  CA  . GLU A 1 214 ? 154.888 153.538 170.997 1.00 131.44 ? 214 GLU A CA  1 
ATOM   1537 C  C   . GLU A 1 214 ? 154.756 152.701 169.731 1.00 131.44 ? 214 GLU A C   1 
ATOM   1538 O  O   . GLU A 1 214 ? 155.473 152.931 168.750 1.00 131.44 ? 214 GLU A O   1 
ATOM   1539 C  CB  . GLU A 1 214 ? 155.819 152.863 172.002 1.00 131.44 ? 214 GLU A CB  1 
ATOM   1540 C  CG  . GLU A 1 214 ? 155.994 153.645 173.295 1.00 131.44 ? 214 GLU A CG  1 
ATOM   1541 C  CD  . GLU A 1 214 ? 156.134 155.137 173.057 1.00 131.44 ? 214 GLU A CD  1 
ATOM   1542 O  OE1 . GLU A 1 214 ? 157.169 155.558 172.500 1.00 131.44 ? 214 GLU A OE1 1 
ATOM   1543 O  OE2 . GLU A 1 214 ? 155.208 155.889 173.427 1.00 131.44 ? 214 GLU A OE2 1 
ATOM   1544 N  N   . ILE A 1 215 ? 153.849 151.721 169.732 1.00 125.65 ? 215 ILE A N   1 
ATOM   1545 C  CA  . ILE A 1 215 ? 153.579 150.980 168.504 1.00 125.65 ? 215 ILE A CA  1 
ATOM   1546 C  C   . ILE A 1 215 ? 152.871 151.873 167.487 1.00 125.65 ? 215 ILE A C   1 
ATOM   1547 O  O   . ILE A 1 215 ? 152.972 151.647 166.275 1.00 125.65 ? 215 ILE A O   1 
ATOM   1548 C  CB  . ILE A 1 215 ? 152.780 149.697 168.817 1.00 125.65 ? 215 ILE A CB  1 
ATOM   1549 C  CG1 . ILE A 1 215 ? 152.785 148.742 167.619 1.00 125.65 ? 215 ILE A CG1 1 
ATOM   1550 C  CG2 . ILE A 1 215 ? 151.356 150.019 169.253 1.00 125.65 ? 215 ILE A CG2 1 
ATOM   1551 C  CD1 . ILE A 1 215 ? 154.166 148.450 167.071 1.00 125.65 ? 215 ILE A CD1 1 
ATOM   1552 N  N   . GLY A 1 216 ? 152.157 152.900 167.955 1.00 128.42 ? 216 GLY A N   1 
ATOM   1553 C  CA  . GLY A 1 216 ? 151.543 153.846 167.037 1.00 128.42 ? 216 GLY A CA  1 
ATOM   1554 C  C   . GLY A 1 216 ? 152.560 154.688 166.291 1.00 128.42 ? 216 GLY A C   1 
ATOM   1555 O  O   . GLY A 1 216 ? 152.354 155.034 165.124 1.00 128.42 ? 216 GLY A O   1 
ATOM   1556 N  N   . LYS A 1 217 ? 153.667 155.039 166.955 1.00 126.18 ? 217 LYS A N   1 
ATOM   1557 C  CA  . LYS A 1 217 ? 154.718 155.805 166.292 1.00 126.18 ? 217 LYS A CA  1 
ATOM   1558 C  C   . LYS A 1 217 ? 155.401 154.994 165.199 1.00 126.18 ? 217 LYS A C   1 
ATOM   1559 O  O   . LYS A 1 217 ? 155.914 155.568 164.232 1.00 126.18 ? 217 LYS A O   1 
ATOM   1560 C  CB  . LYS A 1 217 ? 155.754 156.286 167.310 1.00 126.18 ? 217 LYS A CB  1 
ATOM   1561 C  CG  . LYS A 1 217 ? 155.184 156.658 168.666 1.00 126.18 ? 217 LYS A CG  1 
ATOM   1562 C  CD  . LYS A 1 217 ? 156.100 157.606 169.422 1.00 126.18 ? 217 LYS A CD  1 
ATOM   1563 C  CE  . LYS A 1 217 ? 155.391 158.218 170.621 1.00 126.18 ? 217 LYS A CE  1 
ATOM   1564 N  NZ  . LYS A 1 217 ? 154.394 159.247 170.220 1.00 126.18 ? 217 LYS A NZ  1 
ATOM   1565 N  N   . ILE A 1 218 ? 155.421 153.672 165.332 1.00 126.33 ? 218 ILE A N   1 
ATOM   1566 C  CA  . ILE A 1 218 ? 156.028 152.810 164.329 1.00 126.33 ? 218 ILE A CA  1 
ATOM   1567 C  C   . ILE A 1 218 ? 154.982 152.383 163.307 1.00 126.33 ? 218 ILE A C   1 
ATOM   1568 O  O   . ILE A 1 218 ? 153.783 152.558 163.524 1.00 126.33 ? 218 ILE A O   1 
ATOM   1569 C  CB  . ILE A 1 218 ? 156.691 151.583 164.979 1.00 126.33 ? 218 ILE A CB  1 
ATOM   1570 C  CG1 . ILE A 1 218 ? 157.859 152.011 165.872 1.00 126.33 ? 218 ILE A CG1 1 
ATOM   1571 C  CG2 . ILE A 1 218 ? 157.160 150.604 163.913 1.00 126.33 ? 218 ILE A CG2 1 
ATOM   1572 C  CD1 . ILE A 1 218 ? 158.794 153.019 165.232 1.00 126.33 ? 218 ILE A CD1 1 
ATOM   1573 N  N   . GLN A 1 229 ? 150.469 138.541 148.470 1.00 62.81  ? 229 GLN A N   1 
ATOM   1574 C  CA  . GLN A 1 229 ? 149.368 137.755 147.925 1.00 62.81  ? 229 GLN A CA  1 
ATOM   1575 C  C   . GLN A 1 229 ? 149.408 136.320 148.442 1.00 62.81  ? 229 GLN A C   1 
ATOM   1576 O  O   . GLN A 1 229 ? 150.320 135.938 149.174 1.00 62.81  ? 229 GLN A O   1 
ATOM   1577 C  CB  . GLN A 1 229 ? 149.402 137.769 146.395 1.00 62.81  ? 229 GLN A CB  1 
ATOM   1578 C  CG  . GLN A 1 229 ? 150.699 137.255 145.794 1.00 62.81  ? 229 GLN A CG  1 
ATOM   1579 C  CD  . GLN A 1 229 ? 151.704 138.362 145.542 1.00 62.81  ? 229 GLN A CD  1 
ATOM   1580 O  OE1 . GLN A 1 229 ? 151.334 139.489 145.210 1.00 62.81  ? 229 GLN A OE1 1 
ATOM   1581 N  NE2 . GLN A 1 229 ? 152.984 138.046 145.699 1.00 62.81  ? 229 GLN A NE2 1 
ATOM   1582 N  N   . THR A 1 230 ? 148.411 135.532 148.054 1.00 62.13  ? 230 THR A N   1 
ATOM   1583 C  CA  . THR A 1 230 ? 148.280 134.165 148.531 1.00 62.13  ? 230 THR A CA  1 
ATOM   1584 C  C   . THR A 1 230 ? 149.206 133.227 147.756 1.00 62.13  ? 230 THR A C   1 
ATOM   1585 O  O   . THR A 1 230 ? 149.588 133.522 146.620 1.00 62.13  ? 230 THR A O   1 
ATOM   1586 C  CB  . THR A 1 230 ? 146.837 133.693 148.389 1.00 62.13  ? 230 THR A CB  1 
ATOM   1587 O  OG1 . THR A 1 230 ? 146.440 133.769 147.014 1.00 62.13  ? 230 THR A OG1 1 
ATOM   1588 C  CG2 . THR A 1 230 ? 145.905 134.557 149.227 1.00 62.13  ? 230 THR A CG2 1 
ATOM   1589 N  N   . PRO A 1 231 ? 149.605 132.103 148.364 1.00 63.33  ? 231 PRO A N   1 
ATOM   1590 C  CA  . PRO A 1 231 ? 150.366 131.092 147.609 1.00 63.33  ? 231 PRO A CA  1 
ATOM   1591 C  C   . PRO A 1 231 ? 149.631 130.551 146.395 1.00 63.33  ? 231 PRO A C   1 
ATOM   1592 O  O   . PRO A 1 231 ? 150.275 130.253 145.380 1.00 63.33  ? 231 PRO A O   1 
ATOM   1593 C  CB  . PRO A 1 231 ? 150.614 129.997 148.653 1.00 63.33  ? 231 PRO A CB  1 
ATOM   1594 C  CG  . PRO A 1 231 ? 150.637 130.726 149.946 1.00 63.33  ? 231 PRO A CG  1 
ATOM   1595 C  CD  . PRO A 1 231 ? 149.633 131.840 149.814 1.00 63.33  ? 231 PRO A CD  1 
ATOM   1596 N  N   . LEU A 1 232 ? 148.303 130.408 146.466 1.00 60.28  ? 232 LEU A N   1 
ATOM   1597 C  CA  . LEU A 1 232 ? 147.540 130.050 145.273 1.00 60.28  ? 232 LEU A CA  1 
ATOM   1598 C  C   . LEU A 1 232 ? 147.656 131.136 144.215 1.00 60.28  ? 232 LEU A C   1 
ATOM   1599 O  O   . LEU A 1 232 ? 147.797 130.839 143.024 1.00 60.28  ? 232 LEU A O   1 
ATOM   1600 C  CB  . LEU A 1 232 ? 146.072 129.809 145.625 1.00 60.28  ? 232 LEU A CB  1 
ATOM   1601 C  CG  . LEU A 1 232 ? 145.053 130.033 144.501 1.00 60.28  ? 232 LEU A CG  1 
ATOM   1602 C  CD1 . LEU A 1 232 ? 145.031 128.844 143.550 1.00 60.28  ? 232 LEU A CD1 1 
ATOM   1603 C  CD2 . LEU A 1 232 ? 143.660 130.323 145.041 1.00 60.28  ? 232 LEU A CD2 1 
ATOM   1604 N  N   . GLN A 1 233 ? 147.606 132.402 144.636 1.00 60.78  ? 233 GLN A N   1 
ATOM   1605 C  CA  . GLN A 1 233 ? 147.779 133.504 143.697 1.00 60.78  ? 233 GLN A CA  1 
ATOM   1606 C  C   . GLN A 1 233 ? 149.165 133.477 143.067 1.00 60.78  ? 233 GLN A C   1 
ATOM   1607 O  O   . GLN A 1 233 ? 149.305 133.702 141.862 1.00 60.78  ? 233 GLN A O   1 
ATOM   1608 C  CB  . GLN A 1 233 ? 147.532 134.839 144.399 1.00 60.78  ? 233 GLN A CB  1 
ATOM   1609 C  CG  . GLN A 1 233 ? 146.063 135.164 144.610 1.00 60.78  ? 233 GLN A CG  1 
ATOM   1610 C  CD  . GLN A 1 233 ? 145.724 136.597 144.252 1.00 60.78  ? 233 GLN A CD  1 
ATOM   1611 O  OE1 . GLN A 1 233 ? 146.082 137.082 143.180 1.00 60.78  ? 233 GLN A OE1 1 
ATOM   1612 N  NE2 . GLN A 1 233 ? 145.029 137.283 145.152 1.00 60.78  ? 233 GLN A NE2 1 
ATOM   1613 N  N   . ARG A 1 234 ? 150.201 133.191 143.861 1.00 62.97  ? 234 ARG A N   1 
ATOM   1614 C  CA  . ARG A 1 234 ? 151.555 133.116 143.316 1.00 62.97  ? 234 ARG A CA  1 
ATOM   1615 C  C   . ARG A 1 234 ? 151.692 131.970 142.320 1.00 62.97  ? 234 ARG A C   1 
ATOM   1616 O  O   . ARG A 1 234 ? 152.287 132.137 141.247 1.00 62.97  ? 234 ARG A O   1 
ATOM   1617 C  CB  . ARG A 1 234 ? 152.569 132.961 144.450 1.00 62.97  ? 234 ARG A CB  1 
ATOM   1618 C  CG  . ARG A 1 234 ? 152.716 134.192 145.326 1.00 62.97  ? 234 ARG A CG  1 
ATOM   1619 C  CD  . ARG A 1 234 ? 153.856 134.030 146.317 1.00 62.97  ? 234 ARG A CD  1 
ATOM   1620 N  NE  . ARG A 1 234 ? 153.737 134.953 147.440 1.00 62.97  ? 234 ARG A NE  1 
ATOM   1621 C  CZ  . ARG A 1 234 ? 153.150 134.659 148.592 1.00 62.97  ? 234 ARG A CZ  1 
ATOM   1622 N  NH1 . ARG A 1 234 ? 152.614 133.469 148.811 1.00 62.97  ? 234 ARG A NH1 1 
ATOM   1623 N  NH2 . ARG A 1 234 ? 153.099 135.582 149.549 1.00 62.97  ? 234 ARG A NH2 1 
ATOM   1624 N  N   . LYS A 1 235 ? 151.133 130.802 142.651 1.00 63.52  ? 235 LYS A N   1 
ATOM   1625 C  CA  . LYS A 1 235 ? 151.191 129.668 141.734 1.00 63.52  ? 235 LYS A CA  1 
ATOM   1626 C  C   . LYS A 1 235 ? 150.411 129.952 140.457 1.00 63.52  ? 235 LYS A C   1 
ATOM   1627 O  O   . LYS A 1 235 ? 150.827 129.554 139.363 1.00 63.52  ? 235 LYS A O   1 
ATOM   1628 C  CB  . LYS A 1 235 ? 150.660 128.408 142.418 1.00 63.52  ? 235 LYS A CB  1 
ATOM   1629 C  CG  . LYS A 1 235 ? 151.100 127.107 141.758 1.00 63.52  ? 235 LYS A CG  1 
ATOM   1630 C  CD  . LYS A 1 235 ? 150.014 126.535 140.859 1.00 63.52  ? 235 LYS A CD  1 
ATOM   1631 C  CE  . LYS A 1 235 ? 150.320 125.099 140.466 1.00 63.52  ? 235 LYS A CE  1 
ATOM   1632 N  NZ  . LYS A 1 235 ? 149.170 124.456 139.772 1.00 63.52  ? 235 LYS A NZ  1 
ATOM   1633 N  N   . LEU A 1 236 ? 149.280 130.650 140.573 1.00 59.38  ? 236 LEU A N   1 
ATOM   1634 C  CA  . LEU A 1 236 ? 148.483 130.941 139.390 1.00 59.38  ? 236 LEU A CA  1 
ATOM   1635 C  C   . LEU A 1 236 ? 149.123 132.022 138.530 1.00 59.38  ? 236 LEU A C   1 
ATOM   1636 O  O   . LEU A 1 236 ? 148.985 131.987 137.307 1.00 59.38  ? 236 LEU A O   1 
ATOM   1637 C  CB  . LEU A 1 236 ? 147.062 131.327 139.792 1.00 59.38  ? 236 LEU A CB  1 
ATOM   1638 C  CG  . LEU A 1 236 ? 146.111 130.128 139.743 1.00 59.38  ? 236 LEU A CG  1 
ATOM   1639 C  CD1 . LEU A 1 236 ? 144.722 130.495 140.221 1.00 59.38  ? 236 LEU A CD1 1 
ATOM   1640 C  CD2 . LEU A 1 236 ? 146.061 129.544 138.339 1.00 59.38  ? 236 LEU A CD2 1 
ATOM   1641 N  N   . GLU A 1 237 ? 149.847 132.970 139.132 1.00 64.19  ? 237 GLU A N   1 
ATOM   1642 C  CA  . GLU A 1 237 ? 150.627 133.899 138.316 1.00 64.19  ? 237 GLU A CA  1 
ATOM   1643 C  C   . GLU A 1 237 ? 151.811 133.208 137.652 1.00 64.19  ? 237 GLU A C   1 
ATOM   1644 O  O   . GLU A 1 237 ? 152.181 133.571 136.532 1.00 64.19  ? 237 GLU A O   1 
ATOM   1645 C  CB  . GLU A 1 237 ? 151.108 135.099 139.140 1.00 64.19  ? 237 GLU A CB  1 
ATOM   1646 C  CG  . GLU A 1 237 ? 150.022 135.942 139.825 1.00 64.19  ? 237 GLU A CG  1 
ATOM   1647 C  CD  . GLU A 1 237 ? 149.210 136.834 138.885 1.00 64.19  ? 237 GLU A CD  1 
ATOM   1648 O  OE1 . GLU A 1 237 ? 148.773 137.910 139.345 1.00 64.19  ? 237 GLU A OE1 1 
ATOM   1649 O  OE2 . GLU A 1 237 ? 148.996 136.485 137.705 1.00 64.19  ? 237 GLU A OE2 1 
ATOM   1650 N  N   . SER A 1 238 ? 152.413 132.214 138.313 1.00 62.54  ? 238 SER A N   1 
ATOM   1651 C  CA  . SER A 1 238 ? 153.457 131.430 137.655 1.00 62.54  ? 238 SER A CA  1 
ATOM   1652 C  C   . SER A 1 238 ? 152.896 130.649 136.470 1.00 62.54  ? 238 SER A C   1 
ATOM   1653 O  O   . SER A 1 238 ? 153.506 130.609 135.391 1.00 62.54  ? 238 SER A O   1 
ATOM   1654 C  CB  . SER A 1 238 ? 154.114 130.484 138.659 1.00 62.54  ? 238 SER A CB  1 
ATOM   1655 O  OG  . SER A 1 238 ? 154.825 131.206 139.650 1.00 62.54  ? 238 SER A OG  1 
ATOM   1656 N  N   . PHE A 1 239 ? 151.726 130.032 136.652 1.00 53.31  ? 239 PHE A N   1 
ATOM   1657 C  CA  . PHE A 1 239 ? 151.065 129.337 135.551 1.00 53.31  ? 239 PHE A CA  1 
ATOM   1658 C  C   . PHE A 1 239 ? 150.674 130.310 134.445 1.00 53.31  ? 239 PHE A C   1 
ATOM   1659 O  O   . PHE A 1 239 ? 150.758 129.979 133.258 1.00 53.31  ? 239 PHE A O   1 
ATOM   1660 C  CB  . PHE A 1 239 ? 149.839 128.582 136.067 1.00 53.31  ? 239 PHE A CB  1 
ATOM   1661 C  CG  . PHE A 1 239 ? 148.799 128.311 135.014 1.00 53.31  ? 239 PHE A CG  1 
ATOM   1662 C  CD1 . PHE A 1 239 ? 149.013 127.350 134.039 1.00 53.31  ? 239 PHE A CD1 1 
ATOM   1663 C  CD2 . PHE A 1 239 ? 147.601 129.009 135.008 1.00 53.31  ? 239 PHE A CD2 1 
ATOM   1664 C  CE1 . PHE A 1 239 ? 148.058 127.097 133.072 1.00 53.31  ? 239 PHE A CE1 1 
ATOM   1665 C  CE2 . PHE A 1 239 ? 146.642 128.760 134.043 1.00 53.31  ? 239 PHE A CE2 1 
ATOM   1666 C  CZ  . PHE A 1 239 ? 146.871 127.803 133.075 1.00 53.31  ? 239 PHE A CZ  1 
ATOM   1667 N  N   . SER A 1 240 ? 150.241 131.516 134.820 1.00 57.14  ? 240 SER A N   1 
ATOM   1668 C  CA  . SER A 1 240 ? 149.897 132.534 133.836 1.00 57.14  ? 240 SER A CA  1 
ATOM   1669 C  C   . SER A 1 240 ? 151.119 132.974 133.045 1.00 57.14  ? 240 SER A C   1 
ATOM   1670 O  O   . SER A 1 240 ? 151.026 133.200 131.839 1.00 57.14  ? 240 SER A O   1 
ATOM   1671 C  CB  . SER A 1 240 ? 149.253 133.734 134.525 1.00 57.14  ? 240 SER A CB  1 
ATOM   1672 O  OG  . SER A 1 240 ? 150.234 134.565 135.119 1.00 57.14  ? 240 SER A OG  1 
ATOM   1673 N  N   . LYS A 1 241 ? 152.273 133.103 133.704 1.00 57.24  ? 241 LYS A N   1 
ATOM   1674 C  CA  . LYS A 1 241 ? 153.485 133.489 132.989 1.00 57.24  ? 241 LYS A CA  1 
ATOM   1675 C  C   . LYS A 1 241 ? 153.961 132.368 132.067 1.00 57.24  ? 241 LYS A C   1 
ATOM   1676 O  O   . LYS A 1 241 ? 154.432 132.634 130.954 1.00 57.24  ? 241 LYS A O   1 
ATOM   1677 C  CB  . LYS A 1 241 ? 154.570 133.917 133.988 1.00 57.24  ? 241 LYS A CB  1 
ATOM   1678 C  CG  . LYS A 1 241 ? 155.646 132.887 134.317 1.00 57.24  ? 241 LYS A CG  1 
ATOM   1679 C  CD  . LYS A 1 241 ? 156.419 133.259 135.571 1.00 57.24  ? 241 LYS A CD  1 
ATOM   1680 C  CE  . LYS A 1 241 ? 157.388 132.154 135.961 1.00 57.24  ? 241 LYS A CE  1 
ATOM   1681 N  NZ  . LYS A 1 241 ? 158.153 132.487 137.193 1.00 57.24  ? 241 LYS A NZ  1 
ATOM   1682 N  N   . LYS A 1 242 ? 153.800 131.107 132.489 1.00 53.66  ? 242 LYS A N   1 
ATOM   1683 C  CA  . LYS A 1 242 ? 154.161 129.992 131.616 1.00 53.66  ? 242 LYS A CA  1 
ATOM   1684 C  C   . LYS A 1 242 ? 153.242 129.925 130.402 1.00 53.66  ? 242 LYS A C   1 
ATOM   1685 O  O   . LYS A 1 242 ? 153.708 129.765 129.263 1.00 53.66  ? 242 LYS A O   1 
ATOM   1686 C  CB  . LYS A 1 242 ? 154.118 128.679 132.397 1.00 53.66  ? 242 LYS A CB  1 
ATOM   1687 C  CG  . LYS A 1 242 ? 154.517 127.457 131.585 1.00 53.66  ? 242 LYS A CG  1 
ATOM   1688 C  CD  . LYS A 1 242 ? 155.885 127.637 130.946 1.00 53.66  ? 242 LYS A CD  1 
ATOM   1689 C  CE  . LYS A 1 242 ? 156.220 126.476 130.024 1.00 53.66  ? 242 LYS A CE  1 
ATOM   1690 N  NZ  . LYS A 1 242 ? 157.464 126.727 129.245 1.00 53.66  ? 242 LYS A NZ  1 
ATOM   1691 N  N   . LEU A 1 243 ? 151.933 130.060 130.630 1.00 49.28  ? 243 LEU A N   1 
ATOM   1692 C  CA  . LEU A 1 243 ? 150.977 130.099 129.532 1.00 49.28  ? 243 LEU A CA  1 
ATOM   1693 C  C   . LEU A 1 243 ? 151.205 131.309 128.642 1.00 49.28  ? 243 LEU A C   1 
ATOM   1694 O  O   . LEU A 1 243 ? 151.010 131.223 127.430 1.00 49.28  ? 243 LEU A O   1 
ATOM   1695 C  CB  . LEU A 1 243 ? 149.549 130.102 130.077 1.00 49.28  ? 243 LEU A CB  1 
ATOM   1696 C  CG  . LEU A 1 243 ? 148.442 129.780 129.071 1.00 49.28  ? 243 LEU A CG  1 
ATOM   1697 C  CD1 . LEU A 1 243 ? 148.452 128.300 128.720 1.00 49.28  ? 243 LEU A CD1 1 
ATOM   1698 C  CD2 . LEU A 1 243 ? 147.084 130.200 129.611 1.00 49.28  ? 243 LEU A CD2 1 
ATOM   1699 N  N   . GLY A 1 244 ? 151.625 132.436 129.217 1.00 54.86  ? 244 GLY A N   1 
ATOM   1700 C  CA  . GLY A 1 244 ? 151.916 133.607 128.412 1.00 54.86  ? 244 GLY A CA  1 
ATOM   1701 C  C   . GLY A 1 244 ? 153.111 133.409 127.504 1.00 54.86  ? 244 GLY A C   1 
ATOM   1702 O  O   . GLY A 1 244 ? 153.074 133.787 126.333 1.00 54.86  ? 244 GLY A O   1 
ATOM   1703 N  N   . LEU A 1 245 ? 154.184 132.807 128.028 1.00 61.17  ? 245 LEU A N   1 
ATOM   1704 C  CA  . LEU A 1 245 ? 155.342 132.509 127.189 1.00 61.17  ? 245 LEU A CA  1 
ATOM   1705 C  C   . LEU A 1 245 ? 154.975 131.534 126.075 1.00 61.17  ? 245 LEU A C   1 
ATOM   1706 O  O   . LEU A 1 245 ? 155.315 131.754 124.903 1.00 61.17  ? 245 LEU A O   1 
ATOM   1707 C  CB  . LEU A 1 245 ? 156.484 131.952 128.041 1.00 61.17  ? 245 LEU A CB  1 
ATOM   1708 C  CG  . LEU A 1 245 ? 157.093 132.884 129.091 1.00 61.17  ? 245 LEU A CG  1 
ATOM   1709 C  CD1 . LEU A 1 245 ? 158.338 132.261 129.703 1.00 61.17  ? 245 LEU A CD1 1 
ATOM   1710 C  CD2 . LEU A 1 245 ? 157.410 134.246 128.491 1.00 61.17  ? 245 LEU A CD2 1 
ATOM   1711 N  N   . GLY A 1 246 ? 154.250 130.464 126.419 1.00 59.59  ? 246 GLY A N   1 
ATOM   1712 C  CA  . GLY A 1 246 ? 153.840 129.504 125.403 1.00 59.59  ? 246 GLY A CA  1 
ATOM   1713 C  C   . GLY A 1 246 ? 152.911 130.105 124.363 1.00 59.59  ? 246 GLY A C   1 
ATOM   1714 O  O   . GLY A 1 246 ? 153.053 129.850 123.164 1.00 59.59  ? 246 GLY A O   1 
ATOM   1715 N  N   . ILE A 1 247 ? 151.969 130.939 124.804 1.00 54.14  ? 247 ILE A N   1 
ATOM   1716 C  CA  . ILE A 1 247 ? 151.008 131.545 123.893 1.00 54.14  ? 247 ILE A CA  1 
ATOM   1717 C  C   . ILE A 1 247 ? 151.694 132.557 122.986 1.00 54.14  ? 247 ILE A C   1 
ATOM   1718 O  O   . ILE A 1 247 ? 151.416 132.609 121.786 1.00 54.14  ? 247 ILE A O   1 
ATOM   1719 C  CB  . ILE A 1 247 ? 149.847 132.168 124.693 1.00 54.14  ? 247 ILE A CB  1 
ATOM   1720 C  CG1 . ILE A 1 247 ? 149.048 131.069 125.399 1.00 54.14  ? 247 ILE A CG1 1 
ATOM   1721 C  CG2 . ILE A 1 247 ? 148.939 133.012 123.807 1.00 54.14  ? 247 ILE A CG2 1 
ATOM   1722 C  CD1 . ILE A 1 247 ? 148.054 131.588 126.416 1.00 54.14  ? 247 ILE A CD1 1 
ATOM   1723 N  N   . LEU A 1 248 ? 152.608 133.365 123.533 1.00 57.52  ? 248 LEU A N   1 
ATOM   1724 C  CA  . LEU A 1 248 ? 153.338 134.319 122.704 1.00 57.52  ? 248 LEU A CA  1 
ATOM   1725 C  C   . LEU A 1 248 ? 154.214 133.603 121.685 1.00 57.52  ? 248 LEU A C   1 
ATOM   1726 O  O   . LEU A 1 248 ? 154.341 134.058 120.543 1.00 57.52  ? 248 LEU A O   1 
ATOM   1727 C  CB  . LEU A 1 248 ? 154.174 135.254 123.578 1.00 57.52  ? 248 LEU A CB  1 
ATOM   1728 C  CG  . LEU A 1 248 ? 153.391 136.330 124.334 1.00 57.52  ? 248 LEU A CG  1 
ATOM   1729 C  CD1 . LEU A 1 248 ? 154.294 137.077 125.303 1.00 57.52  ? 248 LEU A CD1 1 
ATOM   1730 C  CD2 . LEU A 1 248 ? 152.727 137.293 123.361 1.00 57.52  ? 248 LEU A CD2 1 
ATOM   1731 N  N   . ALA A 1 249 ? 154.811 132.470 122.071 1.00 61.04  ? 249 ALA A N   1 
ATOM   1732 C  CA  . ALA A 1 249 ? 155.512 131.648 121.089 1.00 61.04  ? 249 ALA A CA  1 
ATOM   1733 C  C   . ALA A 1 249 ? 154.555 131.139 120.016 1.00 61.04  ? 249 ALA A C   1 
ATOM   1734 O  O   . ALA A 1 249 ? 154.911 131.075 118.832 1.00 61.04  ? 249 ALA A O   1 
ATOM   1735 C  CB  . ALA A 1 249 ? 156.213 130.481 121.784 1.00 61.04  ? 249 ALA A CB  1 
ATOM   1736 N  N   . LEU A 1 250 ? 153.330 130.782 120.412 1.00 56.77  ? 250 LEU A N   1 
ATOM   1737 C  CA  . LEU A 1 250 ? 152.339 130.312 119.447 1.00 56.77  ? 250 LEU A CA  1 
ATOM   1738 C  C   . LEU A 1 250 ? 151.948 131.412 118.461 1.00 56.77  ? 250 LEU A C   1 
ATOM   1739 O  O   . LEU A 1 250 ? 151.812 131.157 117.260 1.00 56.77  ? 250 LEU A O   1 
ATOM   1740 C  CB  . LEU A 1 250 ? 151.110 129.773 120.180 1.00 56.77  ? 250 LEU A CB  1 
ATOM   1741 C  CG  . LEU A 1 250 ? 149.981 129.214 119.314 1.00 56.77  ? 250 LEU A CG  1 
ATOM   1742 C  CD1 . LEU A 1 250 ? 149.665 127.782 119.714 1.00 56.77  ? 250 LEU A CD1 1 
ATOM   1743 C  CD2 . LEU A 1 250 ? 148.742 130.087 119.422 1.00 56.77  ? 250 LEU A CD2 1 
ATOM   1744 N  N   . CYS A 1 251 ? 151.762 132.644 118.945 1.00 60.69  ? 251 CYS A N   1 
ATOM   1745 C  CA  . CYS A 1 251 ? 151.438 133.738 118.027 1.00 60.69  ? 251 CYS A CA  1 
ATOM   1746 C  C   . CYS A 1 251 ? 152.636 134.125 117.169 1.00 60.69  ? 251 CYS A C   1 
ATOM   1747 O  O   . CYS A 1 251 ? 152.462 134.588 116.038 1.00 60.69  ? 251 CYS A O   1 
ATOM   1748 C  CB  . CYS A 1 251 ? 150.902 134.974 118.758 1.00 60.69  ? 251 CYS A CB  1 
ATOM   1749 S  SG  . CYS A 1 251 ? 149.957 134.732 120.262 1.00 60.69  ? 251 CYS A SG  1 
ATOM   1750 N  N   . VAL A 1 252 ? 153.856 133.950 117.682 1.00 58.98  ? 252 VAL A N   1 
ATOM   1751 C  CA  . VAL A 1 252 ? 155.039 134.142 116.844 1.00 58.98  ? 252 VAL A CA  1 
ATOM   1752 C  C   . VAL A 1 252 ? 155.045 133.123 115.709 1.00 58.98  ? 252 VAL A C   1 
ATOM   1753 O  O   . VAL A 1 252 ? 155.320 133.456 114.549 1.00 58.98  ? 252 VAL A O   1 
ATOM   1754 C  CB  . VAL A 1 252 ? 156.320 134.064 117.695 1.00 58.98  ? 252 VAL A CB  1 
ATOM   1755 C  CG1 . VAL A 1 252 ? 157.542 133.813 116.822 1.00 58.98  ? 252 VAL A CG1 1 
ATOM   1756 C  CG2 . VAL A 1 252 ? 156.500 135.348 118.489 1.00 58.98  ? 252 VAL A CG2 1 
ATOM   1757 N  N   . LEU A 1 253 ? 154.705 131.871 116.026 1.00 59.05  ? 253 LEU A N   1 
ATOM   1758 C  CA  . LEU A 1 253 ? 154.596 130.835 115.001 1.00 59.05  ? 253 LEU A CA  1 
ATOM   1759 C  C   . LEU A 1 253 ? 153.490 131.160 113.998 1.00 59.05  ? 253 LEU A C   1 
ATOM   1760 O  O   . LEU A 1 253 ? 153.647 130.950 112.791 1.00 59.05  ? 253 LEU A O   1 
ATOM   1761 C  CB  . LEU A 1 253 ? 154.366 129.473 115.667 1.00 59.05  ? 253 LEU A CB  1 
ATOM   1762 C  CG  . LEU A 1 253 ? 153.842 128.264 114.882 1.00 59.05  ? 253 LEU A CG  1 
ATOM   1763 C  CD1 . LEU A 1 253 ? 154.485 127.000 115.421 1.00 59.05  ? 253 LEU A CD1 1 
ATOM   1764 C  CD2 . LEU A 1 253 ? 152.325 128.137 114.979 1.00 59.05  ? 253 LEU A CD2 1 
ATOM   1765 N  N   . ILE A 1 254 ? 152.359 131.672 114.489 1.00 54.70  ? 254 ILE A N   1 
ATOM   1766 C  CA  . ILE A 1 254 ? 151.244 132.032 113.614 1.00 54.70  ? 254 ILE A CA  1 
ATOM   1767 C  C   . ILE A 1 254 ? 151.638 133.170 112.676 1.00 54.70  ? 254 ILE A C   1 
ATOM   1768 O  O   . ILE A 1 254 ? 151.342 133.137 111.473 1.00 54.70  ? 254 ILE A O   1 
ATOM   1769 C  CB  . ILE A 1 254 ? 150.003 132.385 114.459 1.00 54.70  ? 254 ILE A CB  1 
ATOM   1770 C  CG1 . ILE A 1 254 ? 149.418 131.125 115.099 1.00 54.70  ? 254 ILE A CG1 1 
ATOM   1771 C  CG2 . ILE A 1 254 ? 148.945 133.080 113.626 1.00 54.70  ? 254 ILE A CG2 1 
ATOM   1772 C  CD1 . ILE A 1 254 ? 148.156 131.373 115.897 1.00 54.70  ? 254 ILE A CD1 1 
ATOM   1773 N  N   . PHE A 1 255 ? 152.311 134.193 113.209 1.00 57.97  ? 255 PHE A N   1 
ATOM   1774 C  CA  . PHE A 1 255 ? 152.787 135.290 112.373 1.00 57.97  ? 255 PHE A CA  1 
ATOM   1775 C  C   . PHE A 1 255 ? 153.807 134.801 111.354 1.00 57.97  ? 255 PHE A C   1 
ATOM   1776 O  O   . PHE A 1 255 ? 153.820 135.266 110.209 1.00 57.97  ? 255 PHE A O   1 
ATOM   1777 C  CB  . PHE A 1 255 ? 153.384 136.395 113.243 1.00 57.97  ? 255 PHE A CB  1 
ATOM   1778 C  CG  . PHE A 1 255 ? 153.749 137.635 112.479 1.00 57.97  ? 255 PHE A CG  1 
ATOM   1779 C  CD1 . PHE A 1 255 ? 152.770 138.519 112.058 1.00 57.97  ? 255 PHE A CD1 1 
ATOM   1780 C  CD2 . PHE A 1 255 ? 155.072 137.913 112.178 1.00 57.97  ? 255 PHE A CD2 1 
ATOM   1781 C  CE1 . PHE A 1 255 ? 153.104 139.657 111.350 1.00 57.97  ? 255 PHE A CE1 1 
ATOM   1782 C  CE2 . PHE A 1 255 ? 155.412 139.051 111.472 1.00 57.97  ? 255 PHE A CE2 1 
ATOM   1783 C  CZ  . PHE A 1 255 ? 154.427 139.924 111.058 1.00 57.97  ? 255 PHE A CZ  1 
ATOM   1784 N  N   . ALA A 1 256 ? 154.660 133.853 111.749 1.00 56.19  ? 256 ALA A N   1 
ATOM   1785 C  CA  . ALA A 1 256 ? 155.592 133.256 110.798 1.00 56.19  ? 256 ALA A CA  1 
ATOM   1786 C  C   . ALA A 1 256 ? 154.852 132.488 109.709 1.00 56.19  ? 256 ALA A C   1 
ATOM   1787 O  O   . ALA A 1 256 ? 155.294 132.453 108.556 1.00 56.19  ? 256 ALA A O   1 
ATOM   1788 C  CB  . ALA A 1 256 ? 156.574 132.342 111.529 1.00 56.19  ? 256 ALA A CB  1 
ATOM   1789 N  N   . VAL A 1 257 ? 153.727 131.861 110.059 1.00 54.62  ? 257 VAL A N   1 
ATOM   1790 C  CA  . VAL A 1 257 ? 152.930 131.147 109.064 1.00 54.62  ? 257 VAL A CA  1 
ATOM   1791 C  C   . VAL A 1 257 ? 152.326 132.124 108.060 1.00 54.62  ? 257 VAL A C   1 
ATOM   1792 O  O   . VAL A 1 257 ? 152.438 131.931 106.845 1.00 54.62  ? 257 VAL A O   1 
ATOM   1793 C  CB  . VAL A 1 257 ? 151.847 130.294 109.750 1.00 54.62  ? 257 VAL A CB  1 
ATOM   1794 C  CG1 . VAL A 1 257 ? 150.791 129.866 108.745 1.00 54.62  ? 257 VAL A CG1 1 
ATOM   1795 C  CG2 . VAL A 1 257 ? 152.473 129.074 110.401 1.00 54.62  ? 257 VAL A CG2 1 
ATOM   1796 N  N   . GLU A 1 258 ? 151.698 133.200 108.551 1.00 54.88  ? 258 GLU A N   1 
ATOM   1797 C  CA  . GLU A 1 258 ? 151.172 134.217 107.637 1.00 54.88  ? 258 GLU A CA  1 
ATOM   1798 C  C   . GLU A 1 258 ? 152.270 134.902 106.830 1.00 54.88  ? 258 GLU A C   1 
ATOM   1799 O  O   . GLU A 1 258 ? 152.012 135.374 105.717 1.00 54.88  ? 258 GLU A O   1 
ATOM   1800 C  CB  . GLU A 1 258 ? 150.340 135.272 108.374 1.00 54.88  ? 258 GLU A CB  1 
ATOM   1801 C  CG  . GLU A 1 258 ? 148.837 134.996 108.409 1.00 54.88  ? 258 GLU A CG  1 
ATOM   1802 C  CD  . GLU A 1 258 ? 148.420 133.951 109.409 1.00 54.88  ? 258 GLU A CD  1 
ATOM   1803 O  OE1 . GLU A 1 258 ? 147.546 133.127 109.074 1.00 54.88  ? 258 GLU A OE1 1 
ATOM   1804 O  OE2 . GLU A 1 258 ? 148.922 133.984 110.544 1.00 54.88  ? 258 GLU A OE2 1 
ATOM   1805 N  N   . ALA A 1 259 ? 153.490 134.971 107.360 1.00 58.46  ? 259 ALA A N   1 
ATOM   1806 C  CA  . ALA A 1 259 ? 154.574 135.595 106.612 1.00 58.46  ? 259 ALA A CA  1 
ATOM   1807 C  C   . ALA A 1 259 ? 155.101 134.672 105.518 1.00 58.46  ? 259 ALA A C   1 
ATOM   1808 O  O   . ALA A 1 259 ? 155.002 134.983 104.327 1.00 58.46  ? 259 ALA A O   1 
ATOM   1809 C  CB  . ALA A 1 259 ? 155.702 136.001 107.564 1.00 58.46  ? 259 ALA A CB  1 
ATOM   1810 N  N   . GLY A 1 260 ? 155.648 133.520 105.904 1.00 66.70  ? 260 GLY A N   1 
ATOM   1811 C  CA  . GLY A 1 260 ? 156.344 132.654 104.975 1.00 66.70  ? 260 GLY A CA  1 
ATOM   1812 C  C   . GLY A 1 260 ? 155.521 131.600 104.269 1.00 66.70  ? 260 GLY A C   1 
ATOM   1813 O  O   . GLY A 1 260 ? 156.021 130.985 103.323 1.00 66.70  ? 260 GLY A O   1 
ATOM   1814 N  N   . ARG A 1 261 ? 154.278 131.361 104.694 1.00 64.77  ? 261 ARG A N   1 
ATOM   1815 C  CA  . ARG A 1 261 ? 153.492 130.292 104.086 1.00 64.77  ? 261 ARG A CA  1 
ATOM   1816 C  C   . ARG A 1 261 ? 153.033 130.666 102.683 1.00 64.77  ? 261 ARG A C   1 
ATOM   1817 O  O   . ARG A 1 261 ? 153.116 129.847 101.760 1.00 64.77  ? 261 ARG A O   1 
ATOM   1818 C  CB  . ARG A 1 261 ? 152.295 129.950 104.972 1.00 64.77  ? 261 ARG A CB  1 
ATOM   1819 C  CG  . ARG A 1 261 ? 151.697 128.578 104.697 1.00 64.77  ? 261 ARG A CG  1 
ATOM   1820 C  CD  . ARG A 1 261 ? 150.393 128.682 103.925 1.00 64.77  ? 261 ARG A CD  1 
ATOM   1821 N  NE  . ARG A 1 261 ? 149.516 129.710 104.471 1.00 64.77  ? 261 ARG A NE  1 
ATOM   1822 C  CZ  . ARG A 1 261 ? 148.512 129.471 105.303 1.00 64.77  ? 261 ARG A CZ  1 
ATOM   1823 N  NH1 . ARG A 1 261 ? 148.228 128.245 105.708 1.00 64.77  ? 261 ARG A NH1 1 
ATOM   1824 N  NH2 . ARG A 1 261 ? 147.775 130.488 105.740 1.00 64.77  ? 261 ARG A NH2 1 
ATOM   1825 N  N   . VAL A 1 262 ? 152.546 131.892 102.499 1.00 84.50  ? 262 VAL A N   1 
ATOM   1826 C  CA  . VAL A 1 262 ? 152.073 132.317 101.186 1.00 84.50  ? 262 VAL A CA  1 
ATOM   1827 C  C   . VAL A 1 262 ? 152.976 133.399 100.591 1.00 84.50  ? 262 VAL A C   1 
ATOM   1828 O  O   . VAL A 1 262 ? 153.567 133.191 99.525  1.00 84.50  ? 262 VAL A O   1 
ATOM   1829 C  CB  . VAL A 1 262 ? 150.585 132.735 101.246 1.00 84.50  ? 262 VAL A CB  1 
ATOM   1830 C  CG1 . VAL A 1 262 ? 149.730 131.514 101.515 1.00 84.50  ? 262 VAL A CG1 1 
ATOM   1831 C  CG2 . VAL A 1 262 ? 150.311 133.731 102.372 1.00 84.50  ? 262 VAL A CG2 1 
ATOM   1832 N  N   . LEU A 1 263 ? 153.101 134.549 101.263 1.00 98.99  ? 263 LEU A N   1 
ATOM   1833 C  CA  . LEU A 1 263 ? 153.933 135.684 100.863 1.00 98.99  ? 263 LEU A CA  1 
ATOM   1834 C  C   . LEU A 1 263 ? 153.641 136.185 99.446  1.00 98.99  ? 263 LEU A C   1 
ATOM   1835 O  O   . LEU A 1 263 ? 154.459 136.921 98.879  1.00 98.99  ? 263 LEU A O   1 
ATOM   1836 C  CB  . LEU A 1 263 ? 155.428 135.355 101.010 1.00 98.99  ? 263 LEU A CB  1 
ATOM   1837 C  CG  . LEU A 1 263 ? 156.420 136.484 101.323 1.00 98.99  ? 263 LEU A CG  1 
ATOM   1838 C  CD1 . LEU A 1 263 ? 155.887 137.416 102.398 1.00 98.99  ? 263 LEU A CD1 1 
ATOM   1839 C  CD2 . LEU A 1 263 ? 157.769 135.911 101.727 1.00 98.99  ? 263 LEU A CD2 1 
ATOM   1840 N  N   . LEU A 1 264 ? 152.491 135.824 98.873  1.00 124.95 ? 264 LEU A N   1 
ATOM   1841 C  CA  . LEU A 1 264 ? 152.112 136.126 97.480  1.00 124.95 ? 264 LEU A CA  1 
ATOM   1842 C  C   . LEU A 1 264 ? 153.230 135.602 96.578  1.00 124.95 ? 264 LEU A C   1 
ATOM   1843 O  O   . LEU A 1 264 ? 153.695 134.470 96.787  1.00 124.95 ? 264 LEU A O   1 
ATOM   1844 C  CB  . LEU A 1 264 ? 151.788 137.610 97.339  1.00 124.95 ? 264 LEU A CB  1 
ATOM   1845 C  CG  . LEU A 1 264 ? 150.519 138.106 98.034  1.00 124.95 ? 264 LEU A CG  1 
ATOM   1846 C  CD1 . LEU A 1 264 ? 150.412 139.620 97.936  1.00 124.95 ? 264 LEU A CD1 1 
ATOM   1847 C  CD2 . LEU A 1 264 ? 149.287 137.438 97.444  1.00 124.95 ? 264 LEU A CD2 1 
ATOM   1848 N  N   . GLY A 1 265 ? 153.685 136.360 95.591  1.00 143.93 ? 265 GLY A N   1 
ATOM   1849 C  CA  . GLY A 1 265 ? 154.826 135.986 94.779  1.00 143.93 ? 265 GLY A CA  1 
ATOM   1850 C  C   . GLY A 1 265 ? 156.126 136.507 95.351  1.00 143.93 ? 265 GLY A C   1 
ATOM   1851 O  O   . GLY A 1 265 ? 156.250 136.750 96.555  1.00 143.93 ? 265 GLY A O   1 
ATOM   1852 N  N   . ASP A 1 266 ? 157.116 136.679 94.472  1.00 165.59 ? 266 ASP A N   1 
ATOM   1853 C  CA  . ASP A 1 266 ? 158.390 137.244 94.904  1.00 165.59 ? 266 ASP A CA  1 
ATOM   1854 C  C   . ASP A 1 266 ? 158.256 138.726 95.231  1.00 165.59 ? 266 ASP A C   1 
ATOM   1855 O  O   . ASP A 1 266 ? 158.843 139.208 96.207  1.00 165.59 ? 266 ASP A O   1 
ATOM   1856 C  CB  . ASP A 1 266 ? 159.455 137.024 93.830  1.00 165.59 ? 266 ASP A CB  1 
ATOM   1857 C  CG  . ASP A 1 266 ? 160.166 135.693 93.978  1.00 165.59 ? 266 ASP A CG  1 
ATOM   1858 O  OD1 . ASP A 1 266 ? 159.960 135.020 95.010  1.00 165.59 ? 266 ASP A OD1 1 
ATOM   1859 O  OD2 . ASP A 1 266 ? 160.931 135.321 93.064  1.00 165.59 ? 266 ASP A OD2 1 
ATOM   1860 N  N   . ASN A 1 267 ? 157.487 139.465 94.428  1.00 161.06 ? 267 ASN A N   1 
ATOM   1861 C  CA  . ASN A 1 267 ? 157.288 140.885 94.694  1.00 161.06 ? 267 ASN A CA  1 
ATOM   1862 C  C   . ASN A 1 267 ? 156.350 141.112 95.872  1.00 161.06 ? 267 ASN A C   1 
ATOM   1863 O  O   . ASN A 1 267 ? 156.476 142.121 96.575  1.00 161.06 ? 267 ASN A O   1 
ATOM   1864 C  CB  . ASN A 1 267 ? 156.753 141.583 93.443  1.00 161.06 ? 267 ASN A CB  1 
ATOM   1865 C  CG  . ASN A 1 267 ? 155.396 141.057 93.016  1.00 161.06 ? 267 ASN A CG  1 
ATOM   1866 O  OD1 . ASN A 1 267 ? 155.042 139.914 93.303  1.00 161.06 ? 267 ASN A OD1 1 
ATOM   1867 N  ND2 . ASN A 1 267 ? 154.628 141.893 92.327  1.00 161.06 ? 267 ASN A ND2 1 
ATOM   1868 N  N   . SER A 1 268 ? 155.399 140.198 96.083  1.00 142.65 ? 268 SER A N   1 
ATOM   1869 C  CA  . SER A 1 268 ? 154.447 140.216 97.195  1.00 142.65 ? 268 SER A CA  1 
ATOM   1870 C  C   . SER A 1 268 ? 153.567 141.463 97.204  1.00 142.65 ? 268 SER A C   1 
ATOM   1871 O  O   . SER A 1 268 ? 153.046 141.842 98.260  1.00 142.65 ? 268 SER A O   1 
ATOM   1872 C  CB  . SER A 1 268 ? 155.158 140.063 98.545  1.00 142.65 ? 268 SER A CB  1 
ATOM   1873 O  OG  . SER A 1 268 ? 154.317 139.419 99.485  1.00 142.65 ? 268 SER A OG  1 
ATOM   1874 N  N   . ALA A 1 269 ? 153.394 142.095 96.038  1.00 140.51 ? 269 ALA A N   1 
ATOM   1875 C  CA  . ALA A 1 269 ? 152.532 143.260 95.845  1.00 140.51 ? 269 ALA A CA  1 
ATOM   1876 C  C   . ALA A 1 269 ? 152.857 144.398 96.806  1.00 140.51 ? 269 ALA A C   1 
ATOM   1877 O  O   . ALA A 1 269 ? 153.774 145.188 96.560  1.00 140.51 ? 269 ALA A O   1 
ATOM   1878 C  CB  . ALA A 1 269 ? 151.059 142.863 95.979  1.00 140.51 ? 269 ALA A CB  1 
ATOM   1879 N  N   . ASP A 1 270 ? 152.109 144.485 97.903  1.00 130.07 ? 270 ASP A N   1 
ATOM   1880 C  CA  . ASP A 1 270 ? 152.223 145.561 98.883  1.00 130.07 ? 270 ASP A CA  1 
ATOM   1881 C  C   . ASP A 1 270 ? 152.445 144.985 100.276 1.00 130.07 ? 270 ASP A C   1 
ATOM   1882 O  O   . ASP A 1 270 ? 151.759 145.333 101.239 1.00 130.07 ? 270 ASP A O   1 
ATOM   1883 C  CB  . ASP A 1 270 ? 150.987 146.457 98.849  1.00 130.07 ? 270 ASP A CB  1 
ATOM   1884 C  CG  . ASP A 1 270 ? 149.695 145.676 98.989  1.00 130.07 ? 270 ASP A CG  1 
ATOM   1885 O  OD1 . ASP A 1 270 ? 149.681 144.478 98.634  1.00 130.07 ? 270 ASP A OD1 1 
ATOM   1886 O  OD2 . ASP A 1 270 ? 148.693 146.259 99.455  1.00 130.07 ? 270 ASP A OD2 1 
ATOM   1887 N  N   . MET A 1 271 ? 153.425 144.080 100.386 1.00 119.31 ? 271 MET A N   1 
ATOM   1888 C  CA  . MET A 1 271 ? 153.707 143.407 101.653 1.00 119.31 ? 271 MET A CA  1 
ATOM   1889 C  C   . MET A 1 271 ? 154.121 144.386 102.745 1.00 119.31 ? 271 MET A C   1 
ATOM   1890 O  O   . MET A 1 271 ? 153.952 144.092 103.934 1.00 119.31 ? 271 MET A O   1 
ATOM   1891 C  CB  . MET A 1 271 ? 154.805 142.361 101.454 1.00 119.31 ? 271 MET A CB  1 
ATOM   1892 C  CG  . MET A 1 271 ? 154.631 141.067 102.244 1.00 119.31 ? 271 MET A CG  1 
ATOM   1893 S  SD  . MET A 1 271 ? 152.945 140.424 102.267 1.00 119.31 ? 271 MET A SD  1 
ATOM   1894 C  CE  . MET A 1 271 ? 152.468 140.754 103.960 1.00 119.31 ? 271 MET A CE  1 
ATOM   1895 N  N   . ALA A 1 272 ? 154.674 145.542 102.367 1.00 114.93 ? 272 ALA A N   1 
ATOM   1896 C  CA  . ALA A 1 272 ? 155.028 146.556 103.356 1.00 114.93 ? 272 ALA A CA  1 
ATOM   1897 C  C   . ALA A 1 272 ? 153.792 147.078 104.077 1.00 114.93 ? 272 ALA A C   1 
ATOM   1898 O  O   . ALA A 1 272 ? 153.819 147.298 105.294 1.00 114.93 ? 272 ALA A O   1 
ATOM   1899 C  CB  . ALA A 1 272 ? 155.786 147.702 102.685 1.00 114.93 ? 272 ALA A CB  1 
ATOM   1900 N  N   . THR A 1 273 ? 152.697 147.281 103.344 1.00 115.28 ? 273 THR A N   1 
ATOM   1901 C  CA  . THR A 1 273 ? 151.431 147.719 103.918 1.00 115.28 ? 273 THR A CA  1 
ATOM   1902 C  C   . THR A 1 273 ? 150.444 146.567 104.081 1.00 115.28 ? 273 THR A C   1 
ATOM   1903 O  O   . THR A 1 273 ? 149.229 146.788 104.097 1.00 115.28 ? 273 THR A O   1 
ATOM   1904 C  CB  . THR A 1 273 ? 150.815 148.827 103.065 1.00 115.28 ? 273 THR A CB  1 
ATOM   1905 O  OG1 . THR A 1 273 ? 150.535 148.323 101.753 1.00 115.28 ? 273 THR A OG1 1 
ATOM   1906 C  CG2 . THR A 1 273 ? 151.769 150.006 102.956 1.00 115.28 ? 273 THR A CG2 1 
ATOM   1907 N  N   . ALA A 1 274 ? 150.946 145.336 104.199 1.00 96.78  ? 274 ALA A N   1 
ATOM   1908 C  CA  . ALA A 1 274 ? 150.096 144.173 104.400 1.00 96.78  ? 274 ALA A CA  1 
ATOM   1909 C  C   . ALA A 1 274 ? 150.564 143.272 105.534 1.00 96.78  ? 274 ALA A C   1 
ATOM   1910 O  O   . ALA A 1 274 ? 149.890 142.280 105.829 1.00 96.78  ? 274 ALA A O   1 
ATOM   1911 C  CB  . ALA A 1 274 ? 149.989 143.349 103.108 1.00 96.78  ? 274 ALA A CB  1 
ATOM   1912 N  N   . ILE A 1 275 ? 151.703 143.570 106.164 1.00 83.97  ? 275 ILE A N   1 
ATOM   1913 C  CA  . ILE A 1 275 ? 152.068 142.868 107.388 1.00 83.97  ? 275 ILE A CA  1 
ATOM   1914 C  C   . ILE A 1 275 ? 151.225 143.339 108.561 1.00 83.97  ? 275 ILE A C   1 
ATOM   1915 O  O   . ILE A 1 275 ? 151.171 142.659 109.593 1.00 83.97  ? 275 ILE A O   1 
ATOM   1916 C  CB  . ILE A 1 275 ? 153.564 143.044 107.711 1.00 83.97  ? 275 ILE A CB  1 
ATOM   1917 C  CG1 . ILE A 1 275 ? 153.916 144.530 107.837 1.00 83.97  ? 275 ILE A CG1 1 
ATOM   1918 C  CG2 . ILE A 1 275 ? 154.428 142.348 106.669 1.00 83.97  ? 275 ILE A CG2 1 
ATOM   1919 C  CD1 . ILE A 1 275 ? 155.401 144.804 107.968 1.00 83.97  ? 275 ILE A CD1 1 
ATOM   1920 N  N   . LEU A 1 276 ? 150.568 144.496 108.427 1.00 81.98  ? 276 LEU A N   1 
ATOM   1921 C  CA  . LEU A 1 276 ? 149.787 145.042 109.531 1.00 81.98  ? 276 LEU A CA  1 
ATOM   1922 C  C   . LEU A 1 276 ? 148.591 144.157 109.865 1.00 81.98  ? 276 LEU A C   1 
ATOM   1923 O  O   . LEU A 1 276 ? 148.292 143.943 111.042 1.00 81.98  ? 276 LEU A O   1 
ATOM   1924 C  CB  . LEU A 1 276 ? 149.359 146.484 109.224 1.00 81.98  ? 276 LEU A CB  1 
ATOM   1925 C  CG  . LEU A 1 276 ? 148.053 146.900 108.536 1.00 81.98  ? 276 LEU A CG  1 
ATOM   1926 C  CD1 . LEU A 1 276 ? 147.991 148.412 108.447 1.00 81.98  ? 276 LEU A CD1 1 
ATOM   1927 C  CD2 . LEU A 1 276 ? 147.950 146.324 107.134 1.00 81.98  ? 276 LEU A CD2 1 
ATOM   1928 N  N   . ASN A 1 277 ? 147.922 143.591 108.856 1.00 77.67  ? 277 ASN A N   1 
ATOM   1929 C  CA  . ASN A 1 277 ? 146.769 142.745 109.149 1.00 77.67  ? 277 ASN A CA  1 
ATOM   1930 C  C   . ASN A 1 277 ? 147.197 141.402 109.730 1.00 77.67  ? 277 ASN A C   1 
ATOM   1931 O  O   . ASN A 1 277 ? 146.532 140.875 110.627 1.00 77.67  ? 277 ASN A O   1 
ATOM   1932 C  CB  . ASN A 1 277 ? 145.902 142.559 107.901 1.00 77.67  ? 277 ASN A CB  1 
ATOM   1933 C  CG  . ASN A 1 277 ? 146.681 142.046 106.709 1.00 77.67  ? 277 ASN A CG  1 
ATOM   1934 O  OD1 . ASN A 1 277 ? 147.142 142.828 105.879 1.00 77.67  ? 277 ASN A OD1 1 
ATOM   1935 N  ND2 . ASN A 1 277 ? 146.822 140.729 106.610 1.00 77.67  ? 277 ASN A ND2 1 
ATOM   1936 N  N   . ALA A 1 278 ? 148.309 140.839 109.248 1.00 72.79  ? 278 ALA A N   1 
ATOM   1937 C  CA  . ALA A 1 278 ? 148.808 139.587 109.815 1.00 72.79  ? 278 ALA A CA  1 
ATOM   1938 C  C   . ALA A 1 278 ? 149.253 139.773 111.262 1.00 72.79  ? 278 ALA A C   1 
ATOM   1939 O  O   . ALA A 1 278 ? 148.976 138.923 112.122 1.00 72.79  ? 278 ALA A O   1 
ATOM   1940 C  CB  . ALA A 1 278 ? 149.955 139.044 108.964 1.00 72.79  ? 278 ALA A CB  1 
ATOM   1941 N  N   . PHE A 1 279 ? 149.938 140.884 111.551 1.00 69.64  ? 279 PHE A N   1 
ATOM   1942 C  CA  . PHE A 1 279 ? 150.285 141.189 112.933 1.00 69.64  ? 279 PHE A CA  1 
ATOM   1943 C  C   . PHE A 1 279 ? 149.043 141.464 113.766 1.00 69.64  ? 279 PHE A C   1 
ATOM   1944 O  O   . PHE A 1 279 ? 149.021 141.145 114.956 1.00 69.64  ? 279 PHE A O   1 
ATOM   1945 C  CB  . PHE A 1 279 ? 151.240 142.380 112.998 1.00 69.64  ? 279 PHE A CB  1 
ATOM   1946 C  CG  . PHE A 1 279 ? 152.091 142.404 114.237 1.00 69.64  ? 279 PHE A CG  1 
ATOM   1947 C  CD1 . PHE A 1 279 ? 152.255 141.259 115.001 1.00 69.64  ? 279 PHE A CD1 1 
ATOM   1948 C  CD2 . PHE A 1 279 ? 152.717 143.571 114.644 1.00 69.64  ? 279 PHE A CD2 1 
ATOM   1949 C  CE1 . PHE A 1 279 ? 153.032 141.275 116.142 1.00 69.64  ? 279 PHE A CE1 1 
ATOM   1950 C  CE2 . PHE A 1 279 ? 153.496 143.593 115.786 1.00 69.64  ? 279 PHE A CE2 1 
ATOM   1951 C  CZ  . PHE A 1 279 ? 153.653 142.443 116.536 1.00 69.64  ? 279 PHE A CZ  1 
ATOM   1952 N  N   . MET A 1 280 ? 148.003 142.040 113.158 1.00 71.90  ? 280 MET A N   1 
ATOM   1953 C  CA  . MET A 1 280 ? 146.732 142.213 113.850 1.00 71.90  ? 280 MET A CA  1 
ATOM   1954 C  C   . MET A 1 280 ? 146.130 140.869 114.234 1.00 71.90  ? 280 MET A C   1 
ATOM   1955 O  O   . MET A 1 280 ? 145.625 140.703 115.349 1.00 71.90  ? 280 MET A O   1 
ATOM   1956 C  CB  . MET A 1 280 ? 145.762 142.988 112.960 1.00 71.90  ? 280 MET A CB  1 
ATOM   1957 C  CG  . MET A 1 280 ? 145.833 144.491 113.093 1.00 71.90  ? 280 MET A CG  1 
ATOM   1958 S  SD  . MET A 1 280 ? 144.957 145.320 111.759 1.00 71.90  ? 280 MET A SD  1 
ATOM   1959 C  CE  . MET A 1 280 ? 144.884 146.983 112.404 1.00 71.90  ? 280 MET A CE  1 
ATOM   1960 N  N   . PHE A 1 281 ? 146.178 139.899 113.318 1.00 62.86  ? 281 PHE A N   1 
ATOM   1961 C  CA  . PHE A 1 281 ? 145.650 138.568 113.605 1.00 62.86  ? 281 PHE A CA  1 
ATOM   1962 C  C   . PHE A 1 281 ? 146.432 137.901 114.730 1.00 62.86  ? 281 PHE A C   1 
ATOM   1963 O  O   . PHE A 1 281 ? 145.844 137.338 115.660 1.00 62.86  ? 281 PHE A O   1 
ATOM   1964 C  CB  . PHE A 1 281 ? 145.682 137.698 112.347 1.00 62.86  ? 281 PHE A CB  1 
ATOM   1965 C  CG  . PHE A 1 281 ? 144.900 138.259 111.194 1.00 62.86  ? 281 PHE A CG  1 
ATOM   1966 C  CD1 . PHE A 1 281 ? 143.665 138.852 111.397 1.00 62.86  ? 281 PHE A CD1 1 
ATOM   1967 C  CD2 . PHE A 1 281 ? 145.395 138.176 109.901 1.00 62.86  ? 281 PHE A CD2 1 
ATOM   1968 C  CE1 . PHE A 1 281 ? 142.943 139.366 110.332 1.00 62.86  ? 281 PHE A CE1 1 
ATOM   1969 C  CE2 . PHE A 1 281 ? 144.679 138.689 108.834 1.00 62.86  ? 281 PHE A CE2 1 
ATOM   1970 C  CZ  . PHE A 1 281 ? 143.450 139.283 109.050 1.00 62.86  ? 281 PHE A CZ  1 
ATOM   1971 N  N   . ALA A 1 282 ? 147.766 137.974 114.671 1.00 55.37  ? 282 ALA A N   1 
ATOM   1972 C  CA  . ALA A 1 282 ? 148.586 137.360 115.716 1.00 55.37  ? 282 ALA A CA  1 
ATOM   1973 C  C   . ALA A 1 282 ? 148.386 138.047 117.066 1.00 55.37  ? 282 ALA A C   1 
ATOM   1974 O  O   . ALA A 1 282 ? 148.282 137.378 118.105 1.00 55.37  ? 282 ALA A O   1 
ATOM   1975 C  CB  . ALA A 1 282 ? 150.058 137.388 115.308 1.00 55.37  ? 282 ALA A CB  1 
ATOM   1976 N  N   . VAL A 1 283 ? 148.314 139.380 117.071 1.00 53.09  ? 283 VAL A N   1 
ATOM   1977 C  CA  . VAL A 1 283 ? 148.118 140.119 118.312 1.00 53.09  ? 283 VAL A CA  1 
ATOM   1978 C  C   . VAL A 1 283 ? 146.747 139.819 118.903 1.00 53.09  ? 283 VAL A C   1 
ATOM   1979 O  O   . VAL A 1 283 ? 146.622 139.591 120.109 1.00 53.09  ? 283 VAL A O   1 
ATOM   1980 C  CB  . VAL A 1 283 ? 148.329 141.626 118.070 1.00 53.09  ? 283 VAL A CB  1 
ATOM   1981 C  CG1 . VAL A 1 283 ? 147.656 142.457 119.151 1.00 53.09  ? 283 VAL A CG1 1 
ATOM   1982 C  CG2 . VAL A 1 283 ? 149.815 141.942 118.016 1.00 53.09  ? 283 VAL A CG2 1 
ATOM   1983 N  N   . ALA A 1 284 ? 145.705 139.788 118.066 1.00 46.84  ? 284 ALA A N   1 
ATOM   1984 C  CA  . ALA A 1 284 ? 144.371 139.449 118.549 1.00 46.84  ? 284 ALA A CA  1 
ATOM   1985 C  C   . ALA A 1 284 ? 144.310 138.018 119.060 1.00 46.84  ? 284 ALA A C   1 
ATOM   1986 O  O   . ALA A 1 284 ? 143.573 137.731 120.010 1.00 46.84  ? 284 ALA A O   1 
ATOM   1987 C  CB  . ALA A 1 284 ? 143.343 139.665 117.440 1.00 46.84  ? 284 ALA A CB  1 
ATOM   1988 N  N   . VAL A 1 285 ? 145.080 137.112 118.452 1.00 44.85  ? 285 VAL A N   1 
ATOM   1989 C  CA  . VAL A 1 285 ? 145.213 135.762 118.991 1.00 44.85  ? 285 VAL A CA  1 
ATOM   1990 C  C   . VAL A 1 285 ? 145.810 135.817 120.392 1.00 44.85  ? 285 VAL A C   1 
ATOM   1991 O  O   . VAL A 1 285 ? 145.368 135.103 121.300 1.00 44.85  ? 285 VAL A O   1 
ATOM   1992 C  CB  . VAL A 1 285 ? 146.057 134.892 118.037 1.00 44.85  ? 285 VAL A CB  1 
ATOM   1993 C  CG1 . VAL A 1 285 ? 146.779 133.778 118.784 1.00 44.85  ? 285 VAL A CG1 1 
ATOM   1994 C  CG2 . VAL A 1 285 ? 145.194 134.322 116.928 1.00 44.85  ? 285 VAL A CG2 1 
ATOM   1995 N  N   . ALA A 1 286 ? 146.815 136.676 120.590 1.00 48.23  ? 286 ALA A N   1 
ATOM   1996 C  CA  . ALA A 1 286 ? 147.417 136.826 121.916 1.00 48.23  ? 286 ALA A CA  1 
ATOM   1997 C  C   . ALA A 1 286 ? 146.410 137.358 122.934 1.00 48.23  ? 286 ALA A C   1 
ATOM   1998 O  O   . ALA A 1 286 ? 146.317 136.844 124.055 1.00 48.23  ? 286 ALA A O   1 
ATOM   1999 C  CB  . ALA A 1 286 ? 148.641 137.740 121.840 1.00 48.23  ? 286 ALA A CB  1 
ATOM   2000 N  N   . VAL A 1 287 ? 145.639 138.384 122.553 1.00 44.84  ? 287 VAL A N   1 
ATOM   2001 C  CA  . VAL A 1 287 ? 144.613 138.933 123.447 1.00 44.84  ? 287 VAL A CA  1 
ATOM   2002 C  C   . VAL A 1 287 ? 143.568 137.883 123.793 1.00 44.84  ? 287 VAL A C   1 
ATOM   2003 O  O   . VAL A 1 287 ? 143.148 137.768 124.951 1.00 44.84  ? 287 VAL A O   1 
ATOM   2004 C  CB  . VAL A 1 287 ? 143.957 140.193 122.846 1.00 44.84  ? 287 VAL A CB  1 
ATOM   2005 C  CG1 . VAL A 1 287 ? 143.300 141.009 123.933 1.00 44.84  ? 287 VAL A CG1 1 
ATOM   2006 C  CG2 . VAL A 1 287 ? 144.995 141.075 122.225 1.00 44.84  ? 287 VAL A CG2 1 
ATOM   2007 N  N   . ALA A 1 288 ? 143.122 137.110 122.802 1.00 42.11  ? 288 ALA A N   1 
ATOM   2008 C  CA  . ALA A 1 288 ? 142.112 136.094 123.069 1.00 42.11  ? 288 ALA A CA  1 
ATOM   2009 C  C   . ALA A 1 288 ? 142.658 135.000 123.977 1.00 42.11  ? 288 ALA A C   1 
ATOM   2010 O  O   . ALA A 1 288 ? 142.031 134.647 124.981 1.00 42.11  ? 288 ALA A O   1 
ATOM   2011 C  CB  . ALA A 1 288 ? 141.601 135.503 121.755 1.00 42.11  ? 288 ALA A CB  1 
ATOM   2012 N  N   . ALA A 1 289 ? 143.849 134.483 123.665 1.00 44.83  ? 289 ALA A N   1 
ATOM   2013 C  CA  . ALA A 1 289 ? 144.379 133.329 124.383 1.00 44.83  ? 289 ALA A CA  1 
ATOM   2014 C  C   . ALA A 1 289 ? 144.809 133.686 125.799 1.00 44.83  ? 289 ALA A C   1 
ATOM   2015 O  O   . ALA A 1 289 ? 144.674 132.868 126.717 1.00 44.83  ? 289 ALA A O   1 
ATOM   2016 C  CB  . ALA A 1 289 ? 145.548 132.729 123.608 1.00 44.83  ? 289 ALA A CB  1 
ATOM   2017 N  N   . ILE A 1 290 ? 145.341 134.889 125.997 1.00 45.96  ? 290 ILE A N   1 
ATOM   2018 C  CA  . ILE A 1 290 ? 145.808 135.313 127.314 1.00 45.96  ? 290 ILE A CA  1 
ATOM   2019 C  C   . ILE A 1 290 ? 144.608 135.494 128.237 1.00 45.96  ? 290 ILE A C   1 
ATOM   2020 O  O   . ILE A 1 290 ? 143.641 136.172 127.868 1.00 45.96  ? 290 ILE A O   1 
ATOM   2021 C  CB  . ILE A 1 290 ? 146.644 136.599 127.218 1.00 45.96  ? 290 ILE A CB  1 
ATOM   2022 C  CG1 . ILE A 1 290 ? 148.050 136.281 126.704 1.00 45.96  ? 290 ILE A CG1 1 
ATOM   2023 C  CG2 . ILE A 1 290 ? 146.724 137.294 128.565 1.00 45.96  ? 290 ILE A CG2 1 
ATOM   2024 C  CD1 . ILE A 1 290 ? 148.703 135.108 127.396 1.00 45.96  ? 290 ILE A CD1 1 
ATOM   2025 N  N   . PRO A 1 291 ? 144.603 134.871 129.414 1.00 44.96  ? 291 PRO A N   1 
ATOM   2026 C  CA  . PRO A 1 291 ? 143.533 135.132 130.385 1.00 44.96  ? 291 PRO A CA  1 
ATOM   2027 C  C   . PRO A 1 291 ? 143.796 136.380 131.216 1.00 44.96  ? 291 PRO A C   1 
ATOM   2028 O  O   . PRO A 1 291 ? 144.423 136.292 132.277 1.00 44.96  ? 291 PRO A O   1 
ATOM   2029 C  CB  . PRO A 1 291 ? 143.529 133.865 131.248 1.00 44.96  ? 291 PRO A CB  1 
ATOM   2030 C  CG  . PRO A 1 291 ? 144.930 133.340 131.163 1.00 44.96  ? 291 PRO A CG  1 
ATOM   2031 C  CD  . PRO A 1 291 ? 145.521 133.806 129.857 1.00 44.96  ? 291 PRO A CD  1 
ATOM   2032 N  N   . GLU A 1 292 ? 143.325 137.541 130.755 1.00 51.50  ? 292 GLU A N   1 
ATOM   2033 C  CA  . GLU A 1 292 ? 143.608 138.807 131.489 1.00 51.50  ? 292 GLU A CA  1 
ATOM   2034 C  C   . GLU A 1 292 ? 142.838 138.810 132.813 1.00 51.50  ? 292 GLU A C   1 
ATOM   2035 O  O   . GLU A 1 292 ? 143.350 139.393 133.787 1.00 51.50  ? 292 GLU A O   1 
ATOM   2036 C  CB  . GLU A 1 292 ? 143.240 140.022 130.636 1.00 51.50  ? 292 GLU A CB  1 
ATOM   2037 C  CG  . GLU A 1 292 ? 141.804 140.021 130.143 1.00 51.50  ? 292 GLU A CG  1 
ATOM   2038 C  CD  . GLU A 1 292 ? 141.603 139.492 128.733 1.00 51.50  ? 292 GLU A CD  1 
ATOM   2039 O  OE1 . GLU A 1 292 ? 142.554 138.912 128.176 1.00 51.50  ? 292 GLU A OE1 1 
ATOM   2040 O  OE2 . GLU A 1 292 ? 140.489 139.650 128.202 1.00 51.50  ? 292 GLU A OE2 1 
ATOM   2041 N  N   . ALA A 1 293 ? 141.664 138.178 132.848 1.00 45.01  ? 293 ALA A N   1 
ATOM   2042 C  CA  . ALA A 1 293 ? 140.832 138.136 134.037 1.00 45.01  ? 293 ALA A CA  1 
ATOM   2043 C  C   . ALA A 1 293 ? 141.190 136.981 134.956 1.00 45.01  ? 293 ALA A C   1 
ATOM   2044 O  O   . ALA A 1 293 ? 140.346 136.551 135.742 1.00 45.01  ? 293 ALA A O   1 
ATOM   2045 C  CB  . ALA A 1 293 ? 139.356 138.057 133.645 1.00 45.01  ? 293 ALA A CB  1 
ATOM   2046 N  N   . LEU A 1 294 ? 142.414 136.461 134.869 1.00 46.13  ? 294 LEU A N   1 
ATOM   2047 C  CA  . LEU A 1 294 ? 142.831 135.388 135.765 1.00 46.13  ? 294 LEU A CA  1 
ATOM   2048 C  C   . LEU A 1 294 ? 142.919 135.884 137.204 1.00 46.13  ? 294 LEU A C   1 
ATOM   2049 O  O   . LEU A 1 294 ? 142.229 135.373 138.098 1.00 46.13  ? 294 LEU A O   1 
ATOM   2050 C  CB  . LEU A 1 294 ? 144.174 134.822 135.301 1.00 46.13  ? 294 LEU A CB  1 
ATOM   2051 C  CG  . LEU A 1 294 ? 144.593 133.475 135.887 1.00 46.13  ? 294 LEU A CG  1 
ATOM   2052 C  CD1 . LEU A 1 294 ? 143.409 132.536 135.927 1.00 46.13  ? 294 LEU A CD1 1 
ATOM   2053 C  CD2 . LEU A 1 294 ? 145.726 132.871 135.078 1.00 46.13  ? 294 LEU A CD2 1 
ATOM   2054 N  N   . SER A 1 295 ? 143.760 136.894 137.441 1.00 49.98  ? 295 SER A N   1 
ATOM   2055 C  CA  . SER A 1 295 ? 143.876 137.473 138.774 1.00 49.98  ? 295 SER A CA  1 
ATOM   2056 C  C   . SER A 1 295 ? 142.580 138.142 139.206 1.00 49.98  ? 295 SER A C   1 
ATOM   2057 O  O   . SER A 1 295 ? 142.241 138.122 140.396 1.00 49.98  ? 295 SER A O   1 
ATOM   2058 C  CB  . SER A 1 295 ? 145.029 138.475 138.813 1.00 49.98  ? 295 SER A CB  1 
ATOM   2059 O  OG  . SER A 1 295 ? 146.258 137.845 138.501 1.00 49.98  ? 295 SER A OG  1 
ATOM   2060 N  N   . SER A 1 296 ? 141.844 138.731 138.259 1.00 46.50  ? 296 SER A N   1 
ATOM   2061 C  CA  . SER A 1 296 ? 140.544 139.311 138.582 1.00 46.50  ? 296 SER A CA  1 
ATOM   2062 C  C   . SER A 1 296 ? 139.577 138.247 139.082 1.00 46.50  ? 296 SER A C   1 
ATOM   2063 O  O   . SER A 1 296 ? 138.898 138.449 140.093 1.00 46.50  ? 296 SER A O   1 
ATOM   2064 C  CB  . SER A 1 296 ? 139.967 140.024 137.359 1.00 46.50  ? 296 SER A CB  1 
ATOM   2065 O  OG  . SER A 1 296 ? 140.827 141.056 136.913 1.00 46.50  ? 296 SER A OG  1 
ATOM   2066 N  N   . ILE A 1 297 ? 139.520 137.101 138.399 1.00 44.13  ? 297 ILE A N   1 
ATOM   2067 C  CA  . ILE A 1 297 ? 138.655 136.002 138.819 1.00 44.13  ? 297 ILE A CA  1 
ATOM   2068 C  C   . ILE A 1 297 ? 139.067 135.503 140.195 1.00 44.13  ? 297 ILE A C   1 
ATOM   2069 O  O   . ILE A 1 297 ? 138.219 135.290 141.072 1.00 44.13  ? 297 ILE A O   1 
ATOM   2070 C  CB  . ILE A 1 297 ? 138.686 134.872 137.770 1.00 44.13  ? 297 ILE A CB  1 
ATOM   2071 C  CG1 . ILE A 1 297 ? 137.647 135.119 136.680 1.00 44.13  ? 297 ILE A CG1 1 
ATOM   2072 C  CG2 . ILE A 1 297 ? 138.432 133.512 138.406 1.00 44.13  ? 297 ILE A CG2 1 
ATOM   2073 C  CD1 . ILE A 1 297 ? 137.933 134.367 135.403 1.00 44.13  ? 297 ILE A CD1 1 
ATOM   2074 N  N   . VAL A 1 298 ? 140.375 135.333 140.414 1.00 43.80  ? 298 VAL A N   1 
ATOM   2075 C  CA  . VAL A 1 298 ? 140.848 134.815 141.697 1.00 43.80  ? 298 VAL A CA  1 
ATOM   2076 C  C   . VAL A 1 298 ? 140.477 135.767 142.828 1.00 43.80  ? 298 VAL A C   1 
ATOM   2077 O  O   . VAL A 1 298 ? 139.909 135.353 143.845 1.00 43.80  ? 298 VAL A O   1 
ATOM   2078 C  CB  . VAL A 1 298 ? 142.363 134.555 141.650 1.00 43.80  ? 298 VAL A CB  1 
ATOM   2079 C  CG1 . VAL A 1 298 ? 142.868 134.149 143.021 1.00 43.80  ? 298 VAL A CG1 1 
ATOM   2080 C  CG2 . VAL A 1 298 ? 142.673 133.471 140.642 1.00 43.80  ? 298 VAL A CG2 1 
ATOM   2081 N  N   . THR A 1 299 ? 140.747 137.064 142.646 1.00 44.30  ? 299 THR A N   1 
ATOM   2082 C  CA  . THR A 1 299 ? 140.442 138.042 143.688 1.00 44.30  ? 299 THR A CA  1 
ATOM   2083 C  C   . THR A 1 299 ? 138.940 138.158 143.924 1.00 44.30  ? 299 THR A C   1 
ATOM   2084 O  O   . THR A 1 299 ? 138.492 138.267 145.073 1.00 44.30  ? 299 THR A O   1 
ATOM   2085 C  CB  . THR A 1 299 ? 141.033 139.403 143.318 1.00 44.30  ? 299 THR A CB  1 
ATOM   2086 O  OG1 . THR A 1 299 ? 142.410 139.245 142.957 1.00 44.30  ? 299 THR A OG1 1 
ATOM   2087 C  CG2 . THR A 1 299 ? 140.932 140.367 144.491 1.00 44.30  ? 299 THR A CG2 1 
ATOM   2088 N  N   . ILE A 1 300 ? 138.145 138.116 142.851 1.00 48.56  ? 300 ILE A N   1 
ATOM   2089 C  CA  . ILE A 1 300 ? 136.698 138.257 142.979 1.00 48.56  ? 300 ILE A CA  1 
ATOM   2090 C  C   . ILE A 1 300 ? 136.111 137.081 143.748 1.00 48.56  ? 300 ILE A C   1 
ATOM   2091 O  O   . ILE A 1 300 ? 135.290 137.260 144.659 1.00 48.56  ? 300 ILE A O   1 
ATOM   2092 C  CB  . ILE A 1 300 ? 136.055 138.404 141.586 1.00 48.56  ? 300 ILE A CB  1 
ATOM   2093 C  CG1 . ILE A 1 300 ? 136.209 139.841 141.086 1.00 48.56  ? 300 ILE A CG1 1 
ATOM   2094 C  CG2 . ILE A 1 300 ? 134.586 138.006 141.615 1.00 48.56  ? 300 ILE A CG2 1 
ATOM   2095 C  CD1 . ILE A 1 300 ? 136.074 140.001 139.594 1.00 48.56  ? 300 ILE A CD1 1 
ATOM   2096 N  N   . VAL A 1 301 ? 136.531 135.860 143.409 1.00 43.27  ? 301 VAL A N   1 
ATOM   2097 C  CA  . VAL A 1 301 ? 135.958 134.713 144.100 1.00 43.27  ? 301 VAL A CA  1 
ATOM   2098 C  C   . VAL A 1 301 ? 136.523 134.580 145.507 1.00 43.27  ? 301 VAL A C   1 
ATOM   2099 O  O   . VAL A 1 301 ? 135.852 134.035 146.381 1.00 43.27  ? 301 VAL A O   1 
ATOM   2100 C  CB  . VAL A 1 301 ? 136.144 133.415 143.297 1.00 43.27  ? 301 VAL A CB  1 
ATOM   2101 C  CG1 . VAL A 1 301 ? 135.659 133.591 141.866 1.00 43.27  ? 301 VAL A CG1 1 
ATOM   2102 C  CG2 . VAL A 1 301 ? 137.573 132.989 143.343 1.00 43.27  ? 301 VAL A CG2 1 
ATOM   2103 N  N   . LEU A 1 302 ? 137.732 135.089 145.775 1.00 45.07  ? 302 LEU A N   1 
ATOM   2104 C  CA  . LEU A 1 302 ? 138.193 135.114 147.162 1.00 45.07  ? 302 LEU A CA  1 
ATOM   2105 C  C   . LEU A 1 302 ? 137.392 136.108 147.991 1.00 45.07  ? 302 LEU A C   1 
ATOM   2106 O  O   . LEU A 1 302 ? 137.062 135.830 149.149 1.00 45.07  ? 302 LEU A O   1 
ATOM   2107 C  CB  . LEU A 1 302 ? 139.690 135.422 147.247 1.00 45.07  ? 302 LEU A CB  1 
ATOM   2108 C  CG  . LEU A 1 302 ? 140.685 134.370 146.745 1.00 45.07  ? 302 LEU A CG  1 
ATOM   2109 C  CD1 . LEU A 1 302 ? 142.046 134.565 147.397 1.00 45.07  ? 302 LEU A CD1 1 
ATOM   2110 C  CD2 . LEU A 1 302 ? 140.168 132.965 146.998 1.00 45.07  ? 302 LEU A CD2 1 
ATOM   2111 N  N   . ALA A 1 303 ? 137.059 137.266 147.415 1.00 56.20  ? 303 ALA A N   1 
ATOM   2112 C  CA  . ALA A 1 303 ? 136.217 138.223 148.127 1.00 56.20  ? 303 ALA A CA  1 
ATOM   2113 C  C   . ALA A 1 303 ? 134.828 137.653 148.390 1.00 56.20  ? 303 ALA A C   1 
ATOM   2114 O  O   . ALA A 1 303 ? 134.305 137.758 149.509 1.00 56.20  ? 303 ALA A O   1 
ATOM   2115 C  CB  . ALA A 1 303 ? 136.120 139.525 147.333 1.00 56.20  ? 303 ALA A CB  1 
ATOM   2116 N  N   . VAL A 1 304 ? 134.223 137.025 147.378 1.00 56.96  ? 304 VAL A N   1 
ATOM   2117 C  CA  . VAL A 1 304 ? 132.890 136.464 147.573 1.00 56.96  ? 304 VAL A CA  1 
ATOM   2118 C  C   . VAL A 1 304 ? 132.946 135.241 148.484 1.00 56.96  ? 304 VAL A C   1 
ATOM   2119 O  O   . VAL A 1 304 ? 132.006 134.987 149.245 1.00 56.96  ? 304 VAL A O   1 
ATOM   2120 C  CB  . VAL A 1 304 ? 132.211 136.166 146.219 1.00 56.96  ? 304 VAL A CB  1 
ATOM   2121 C  CG1 . VAL A 1 304 ? 132.591 134.795 145.673 1.00 56.96  ? 304 VAL A CG1 1 
ATOM   2122 C  CG2 . VAL A 1 304 ? 130.703 136.274 146.363 1.00 56.96  ? 304 VAL A CG2 1 
ATOM   2123 N  N   . GLY A 1 305 ? 134.055 134.497 148.471 1.00 55.38  ? 305 GLY A N   1 
ATOM   2124 C  CA  . GLY A 1 305 ? 134.205 133.395 149.399 1.00 55.38  ? 305 GLY A CA  1 
ATOM   2125 C  C   . GLY A 1 305 ? 134.319 133.872 150.829 1.00 55.38  ? 305 GLY A C   1 
ATOM   2126 O  O   . GLY A 1 305 ? 133.690 133.310 151.719 1.00 55.38  ? 305 GLY A O   1 
ATOM   2127 N  N   . THR A 1 306 ? 135.100 134.932 151.059 1.00 59.44  ? 306 THR A N   1 
ATOM   2128 C  CA  . THR A 1 306 ? 135.213 135.513 152.394 1.00 59.44  ? 306 THR A CA  1 
ATOM   2129 C  C   . THR A 1 306 ? 133.872 136.054 152.876 1.00 59.44  ? 306 THR A C   1 
ATOM   2130 O  O   . THR A 1 306 ? 133.515 135.901 154.052 1.00 59.44  ? 306 THR A O   1 
ATOM   2131 C  CB  . THR A 1 306 ? 136.275 136.616 152.390 1.00 59.44  ? 306 THR A CB  1 
ATOM   2132 O  OG1 . THR A 1 306 ? 137.540 136.059 152.013 1.00 59.44  ? 306 THR A OG1 1 
ATOM   2133 C  CG2 . THR A 1 306 ? 136.401 137.258 153.763 1.00 59.44  ? 306 THR A CG2 1 
ATOM   2134 N  N   . ASN A 1 307 ? 133.106 136.675 151.975 1.00 64.99  ? 307 ASN A N   1 
ATOM   2135 C  CA  . ASN A 1 307 ? 131.761 137.115 152.334 1.00 64.99  ? 307 ASN A CA  1 
ATOM   2136 C  C   . ASN A 1 307 ? 130.861 135.931 152.670 1.00 64.99  ? 307 ASN A C   1 
ATOM   2137 O  O   . ASN A 1 307 ? 130.016 136.023 153.569 1.00 64.99  ? 307 ASN A O   1 
ATOM   2138 C  CB  . ASN A 1 307 ? 131.162 137.946 151.203 1.00 64.99  ? 307 ASN A CB  1 
ATOM   2139 C  CG  . ASN A 1 307 ? 131.602 139.392 151.255 1.00 64.99  ? 307 ASN A CG  1 
ATOM   2140 O  OD1 . ASN A 1 307 ? 130.795 140.290 151.492 1.00 64.99  ? 307 ASN A OD1 1 
ATOM   2141 N  ND2 . ASN A 1 307 ? 132.891 139.625 151.040 1.00 64.99  ? 307 ASN A ND2 1 
ATOM   2142 N  N   . LYS A 1 308 ? 131.025 134.813 151.958 1.00 57.27  ? 308 LYS A N   1 
ATOM   2143 C  CA  . LYS A 1 308 ? 130.256 133.610 152.267 1.00 57.27  ? 308 LYS A CA  1 
ATOM   2144 C  C   . LYS A 1 308 ? 130.654 133.025 153.620 1.00 57.27  ? 308 LYS A C   1 
ATOM   2145 O  O   . LYS A 1 308 ? 129.804 132.512 154.358 1.00 57.27  ? 308 LYS A O   1 
ATOM   2146 C  CB  . LYS A 1 308 ? 130.440 132.576 151.156 1.00 57.27  ? 308 LYS A CB  1 
ATOM   2147 C  CG  . LYS A 1 308 ? 129.425 131.445 151.195 1.00 57.27  ? 308 LYS A CG  1 
ATOM   2148 C  CD  . LYS A 1 308 ? 128.026 131.965 150.912 1.00 57.27  ? 308 LYS A CD  1 
ATOM   2149 C  CE  . LYS A 1 308 ? 127.928 132.587 149.527 1.00 57.27  ? 308 LYS A CE  1 
ATOM   2150 N  NZ  . LYS A 1 308 ? 126.615 133.254 149.314 1.00 57.27  ? 308 LYS A NZ  1 
ATOM   2151 N  N   . MET A 1 309 ? 131.948 133.071 153.950 1.00 61.01  ? 309 MET A N   1 
ATOM   2152 C  CA  . MET A 1 309 ? 132.402 132.646 155.273 1.00 61.01  ? 309 MET A CA  1 
ATOM   2153 C  C   . MET A 1 309 ? 131.802 133.527 156.359 1.00 61.01  ? 309 MET A C   1 
ATOM   2154 O  O   . MET A 1 309 ? 131.406 133.035 157.423 1.00 61.01  ? 309 MET A O   1 
ATOM   2155 C  CB  . MET A 1 309 ? 133.930 132.692 155.365 1.00 61.01  ? 309 MET A CB  1 
ATOM   2156 C  CG  . MET A 1 309 ? 134.683 132.041 154.241 1.00 61.01  ? 309 MET A CG  1 
ATOM   2157 S  SD  . MET A 1 309 ? 136.335 131.479 154.656 1.00 61.01  ? 309 MET A SD  1 
ATOM   2158 C  CE  . MET A 1 309 ? 136.001 129.758 154.965 1.00 61.01  ? 309 MET A CE  1 
ATOM   2159 N  N   . ALA A 1 310 ? 131.738 134.836 156.106 1.00 60.71  ? 310 ALA A N   1 
ATOM   2160 C  CA  . ALA A 1 310 ? 131.098 135.747 157.048 1.00 60.71  ? 310 ALA A CA  1 
ATOM   2161 C  C   . ALA A 1 310 ? 129.617 135.426 157.197 1.00 60.71  ? 310 ALA A C   1 
ATOM   2162 O  O   . ALA A 1 310 ? 129.067 135.501 158.301 1.00 60.71  ? 310 ALA A O   1 
ATOM   2163 C  CB  . ALA A 1 310 ? 131.297 137.194 156.599 1.00 60.71  ? 310 ALA A CB  1 
ATOM   2164 N  N   . LYS A 1 311 ? 128.955 135.065 156.094 1.00 58.12  ? 311 LYS A N   1 
ATOM   2165 C  CA  . LYS A 1 311 ? 127.577 134.593 156.180 1.00 58.12  ? 311 LYS A CA  1 
ATOM   2166 C  C   . LYS A 1 311 ? 127.482 133.277 156.938 1.00 58.12  ? 311 LYS A C   1 
ATOM   2167 O  O   . LYS A 1 311 ? 126.462 133.007 157.583 1.00 58.12  ? 311 LYS A O   1 
ATOM   2168 C  CB  . LYS A 1 311 ? 126.981 134.435 154.782 1.00 58.12  ? 311 LYS A CB  1 
ATOM   2169 C  CG  . LYS A 1 311 ? 126.748 135.746 154.051 1.00 58.12  ? 311 LYS A CG  1 
ATOM   2170 C  CD  . LYS A 1 311 ? 125.915 135.534 152.798 1.00 58.12  ? 311 LYS A CD  1 
ATOM   2171 C  CE  . LYS A 1 311 ? 126.005 136.731 151.869 1.00 58.12  ? 311 LYS A CE  1 
ATOM   2172 N  NZ  . LYS A 1 311 ? 127.405 136.991 151.433 1.00 58.12  ? 311 LYS A NZ  1 
ATOM   2173 N  N   . GLN A 1 312 ? 128.527 132.448 156.876 1.00 55.92  ? 312 GLN A N   1 
ATOM   2174 C  CA  . GLN A 1 312 ? 128.546 131.154 157.547 1.00 55.92  ? 312 GLN A CA  1 
ATOM   2175 C  C   . GLN A 1 312 ? 129.160 131.223 158.942 1.00 55.92  ? 312 GLN A C   1 
ATOM   2176 O  O   . GLN A 1 312 ? 129.670 130.206 159.434 1.00 55.92  ? 312 GLN A O   1 
ATOM   2177 C  CB  . GLN A 1 312 ? 129.289 130.129 156.688 1.00 55.92  ? 312 GLN A CB  1 
ATOM   2178 C  CG  . GLN A 1 312 ? 128.496 129.629 155.490 1.00 55.92  ? 312 GLN A CG  1 
ATOM   2179 C  CD  . GLN A 1 312 ? 127.320 128.756 155.883 1.00 55.92  ? 312 GLN A CD  1 
ATOM   2180 O  OE1 . GLN A 1 312 ? 127.312 128.150 156.954 1.00 55.92  ? 312 GLN A OE1 1 
ATOM   2181 N  NE2 . GLN A 1 312 ? 126.318 128.687 155.014 1.00 55.92  ? 312 GLN A NE2 1 
ATOM   2182 N  N   . HIS A 1 313 ? 129.119 132.397 159.583 1.00 57.22  ? 313 HIS A N   1 
ATOM   2183 C  CA  . HIS A 1 313 ? 129.631 132.605 160.944 1.00 57.22  ? 313 HIS A CA  1 
ATOM   2184 C  C   . HIS A 1 313 ? 131.105 132.219 161.061 1.00 57.22  ? 313 HIS A C   1 
ATOM   2185 O  O   . HIS A 1 313 ? 131.523 131.582 162.029 1.00 57.22  ? 313 HIS A O   1 
ATOM   2186 C  CB  . HIS A 1 313 ? 128.796 131.858 161.991 1.00 57.22  ? 313 HIS A CB  1 
ATOM   2187 C  CG  . HIS A 1 313 ? 127.316 132.046 161.848 1.00 57.22  ? 313 HIS A CG  1 
ATOM   2188 N  ND1 . HIS A 1 313 ? 126.597 131.563 160.776 1.00 57.22  ? 313 HIS A ND1 1 
ATOM   2189 C  CD2 . HIS A 1 313 ? 126.420 132.669 162.650 1.00 57.22  ? 313 HIS A CD2 1 
ATOM   2190 C  CE1 . HIS A 1 313 ? 125.323 131.879 160.923 1.00 57.22  ? 313 HIS A CE1 1 
ATOM   2191 N  NE2 . HIS A 1 313 ? 125.189 132.550 162.052 1.00 57.22  ? 313 HIS A NE2 1 
ATOM   2192 N  N   . ALA A 1 314 ? 131.899 132.606 160.065 1.00 57.37  ? 314 ALA A N   1 
ATOM   2193 C  CA  . ALA A 1 314 ? 133.317 132.250 160.018 1.00 57.37  ? 314 ALA A CA  1 
ATOM   2194 C  C   . ALA A 1 314 ? 134.103 133.463 159.528 1.00 57.37  ? 314 ALA A C   1 
ATOM   2195 O  O   . ALA A 1 314 ? 134.226 133.682 158.322 1.00 57.37  ? 314 ALA A O   1 
ATOM   2196 C  CB  . ALA A 1 314 ? 133.541 131.041 159.119 1.00 57.37  ? 314 ALA A CB  1 
ATOM   2197 N  N   . ILE A 1 315 ? 134.632 134.249 160.459 1.00 66.99  ? 315 ILE A N   1 
ATOM   2198 C  CA  . ILE A 1 315 ? 135.410 135.437 160.118 1.00 66.99  ? 315 ILE A CA  1 
ATOM   2199 C  C   . ILE A 1 315 ? 136.858 135.005 159.922 1.00 66.99  ? 315 ILE A C   1 
ATOM   2200 O  O   . ILE A 1 315 ? 137.554 134.676 160.885 1.00 66.99  ? 315 ILE A O   1 
ATOM   2201 C  CB  . ILE A 1 315 ? 135.290 136.523 161.195 1.00 66.99  ? 315 ILE A CB  1 
ATOM   2202 C  CG1 . ILE A 1 315 ? 133.860 137.079 161.294 1.00 66.99  ? 315 ILE A CG1 1 
ATOM   2203 C  CG2 . ILE A 1 315 ? 136.273 137.654 160.932 1.00 66.99  ? 315 ILE A CG2 1 
ATOM   2204 C  CD1 . ILE A 1 315 ? 133.024 137.013 160.020 1.00 66.99  ? 315 ILE A CD1 1 
ATOM   2205 N  N   . ILE A 1 316 ? 137.319 135.007 158.677 1.00 56.71  ? 316 ILE A N   1 
ATOM   2206 C  CA  . ILE A 1 316 ? 138.668 134.557 158.358 1.00 56.71  ? 316 ILE A CA  1 
ATOM   2207 C  C   . ILE A 1 316 ? 139.627 135.737 158.459 1.00 56.71  ? 316 ILE A C   1 
ATOM   2208 O  O   . ILE A 1 316 ? 139.373 136.814 157.906 1.00 56.71  ? 316 ILE A O   1 
ATOM   2209 C  CB  . ILE A 1 316 ? 138.719 133.895 156.969 1.00 56.71  ? 316 ILE A CB  1 
ATOM   2210 C  CG1 . ILE A 1 316 ? 140.165 133.584 156.572 1.00 56.71  ? 316 ILE A CG1 1 
ATOM   2211 C  CG2 . ILE A 1 316 ? 138.008 134.740 155.921 1.00 56.71  ? 316 ILE A CG2 1 
ATOM   2212 C  CD1 . ILE A 1 316 ? 140.293 132.443 155.592 1.00 56.71  ? 316 ILE A CD1 1 
ATOM   2213 N  N   . ARG A 1 317 ? 140.721 135.541 159.195 1.00 60.88  ? 317 ARG A N   1 
ATOM   2214 C  CA  . ARG A 1 317 ? 141.704 136.595 159.421 1.00 60.88  ? 317 ARG A CA  1 
ATOM   2215 C  C   . ARG A 1 317 ? 142.799 136.579 158.359 1.00 60.88  ? 317 ARG A C   1 
ATOM   2216 O  O   . ARG A 1 317 ? 143.034 137.586 157.684 1.00 60.88  ? 317 ARG A O   1 
ATOM   2217 C  CB  . ARG A 1 317 ? 142.306 136.451 160.823 1.00 60.88  ? 317 ARG A CB  1 
ATOM   2218 C  CG  . ARG A 1 317 ? 141.686 137.371 161.861 1.00 60.88  ? 317 ARG A CG  1 
ATOM   2219 C  CD  . ARG A 1 317 ? 142.574 137.506 163.089 1.00 60.88  ? 317 ARG A CD  1 
ATOM   2220 N  NE  . ARG A 1 317 ? 143.886 138.056 162.768 1.00 60.88  ? 317 ARG A NE  1 
ATOM   2221 C  CZ  . ARG A 1 317 ? 145.018 137.368 162.817 1.00 60.88  ? 317 ARG A CZ  1 
ATOM   2222 N  NH1 . ARG A 1 317 ? 145.038 136.092 163.167 1.00 60.88  ? 317 ARG A NH1 1 
ATOM   2223 N  NH2 . ARG A 1 317 ? 146.160 137.974 162.504 1.00 60.88  ? 317 ARG A NH2 1 
ATOM   2224 N  N   . LYS A 1 318 ? 143.475 135.444 158.200 1.00 52.53  ? 318 LYS A N   1 
ATOM   2225 C  CA  . LYS A 1 318 ? 144.559 135.325 157.231 1.00 52.53  ? 318 LYS A CA  1 
ATOM   2226 C  C   . LYS A 1 318 ? 143.963 135.124 155.843 1.00 52.53  ? 318 LYS A C   1 
ATOM   2227 O  O   . LYS A 1 318 ? 143.320 134.104 155.577 1.00 52.53  ? 318 LYS A O   1 
ATOM   2228 C  CB  . LYS A 1 318 ? 145.488 134.175 157.604 1.00 52.53  ? 318 LYS A CB  1 
ATOM   2229 C  CG  . LYS A 1 318 ? 146.954 134.566 157.700 1.00 52.53  ? 318 LYS A CG  1 
ATOM   2230 C  CD  . LYS A 1 318 ? 147.775 133.469 158.358 1.00 52.53  ? 318 LYS A CD  1 
ATOM   2231 C  CE  . LYS A 1 318 ? 148.539 133.999 159.560 1.00 52.53  ? 318 LYS A CE  1 
ATOM   2232 N  NZ  . LYS A 1 318 ? 149.202 132.907 160.326 1.00 52.53  ? 318 LYS A NZ  1 
ATOM   2233 N  N   . LEU A 1 319 ? 144.163 136.109 154.969 1.00 52.99  ? 319 LEU A N   1 
ATOM   2234 C  CA  . LEU A 1 319 ? 143.702 135.991 153.587 1.00 52.99  ? 319 LEU A CA  1 
ATOM   2235 C  C   . LEU A 1 319 ? 144.290 134.805 152.819 1.00 52.99  ? 319 LEU A C   1 
ATOM   2236 O  O   . LEU A 1 319 ? 143.530 134.171 152.066 1.00 52.99  ? 319 LEU A O   1 
ATOM   2237 C  CB  . LEU A 1 319 ? 143.961 137.308 152.841 1.00 52.99  ? 319 LEU A CB  1 
ATOM   2238 C  CG  . LEU A 1 319 ? 142.770 138.263 152.723 1.00 52.99  ? 319 LEU A CG  1 
ATOM   2239 C  CD1 . LEU A 1 319 ? 141.622 137.589 151.986 1.00 52.99  ? 319 LEU A CD1 1 
ATOM   2240 C  CD2 . LEU A 1 319 ? 142.316 138.760 154.088 1.00 52.99  ? 319 LEU A CD2 1 
ATOM   2241 N  N   . PRO A 1 320 ? 145.581 134.452 152.925 1.00 49.28  ? 320 PRO A N   1 
ATOM   2242 C  CA  . PRO A 1 320 ? 146.067 133.269 152.193 1.00 49.28  ? 320 PRO A CA  1 
ATOM   2243 C  C   . PRO A 1 320 ? 145.515 131.934 152.681 1.00 49.28  ? 320 PRO A C   1 
ATOM   2244 O  O   . PRO A 1 320 ? 145.912 130.896 152.141 1.00 49.28  ? 320 PRO A O   1 
ATOM   2245 C  CB  . PRO A 1 320 ? 147.587 133.331 152.403 1.00 49.28  ? 320 PRO A CB  1 
ATOM   2246 C  CG  . PRO A 1 320 ? 147.869 134.750 152.652 1.00 49.28  ? 320 PRO A CG  1 
ATOM   2247 C  CD  . PRO A 1 320 ? 146.721 135.208 153.483 1.00 49.28  ? 320 PRO A CD  1 
ATOM   2248 N  N   . ALA A 1 321 ? 144.627 131.910 153.674 1.00 48.98  ? 321 ALA A N   1 
ATOM   2249 C  CA  . ALA A 1 321 ? 144.095 130.651 154.177 1.00 48.98  ? 321 ALA A CA  1 
ATOM   2250 C  C   . ALA A 1 321 ? 142.848 130.182 153.437 1.00 48.98  ? 321 ALA A C   1 
ATOM   2251 O  O   . ALA A 1 321 ? 142.365 129.081 153.720 1.00 48.98  ? 321 ALA A O   1 
ATOM   2252 C  CB  . ALA A 1 321 ? 143.783 130.773 155.671 1.00 48.98  ? 321 ALA A CB  1 
ATOM   2253 N  N   . VAL A 1 322 ? 142.321 130.979 152.504 1.00 49.33  ? 322 VAL A N   1 
ATOM   2254 C  CA  . VAL A 1 322 ? 141.081 130.614 151.822 1.00 49.33  ? 322 VAL A CA  1 
ATOM   2255 C  C   . VAL A 1 322 ? 141.298 129.421 150.899 1.00 49.33  ? 322 VAL A C   1 
ATOM   2256 O  O   . VAL A 1 322 ? 140.448 128.525 150.812 1.00 49.33  ? 322 VAL A O   1 
ATOM   2257 C  CB  . VAL A 1 322 ? 140.516 131.822 151.053 1.00 49.33  ? 322 VAL A CB  1 
ATOM   2258 C  CG1 . VAL A 1 322 ? 139.128 131.510 150.520 1.00 49.33  ? 322 VAL A CG1 1 
ATOM   2259 C  CG2 . VAL A 1 322 ? 140.475 133.047 151.944 1.00 49.33  ? 322 VAL A CG2 1 
ATOM   2260 N  N   . GLU A 1 323 ? 142.430 129.390 150.192 1.00 51.95  ? 323 GLU A N   1 
ATOM   2261 C  CA  . GLU A 1 323 ? 142.647 128.358 149.183 1.00 51.95  ? 323 GLU A CA  1 
ATOM   2262 C  C   . GLU A 1 323 ? 142.834 126.980 149.811 1.00 51.95  ? 323 GLU A C   1 
ATOM   2263 O  O   . GLU A 1 323 ? 142.344 125.979 149.274 1.00 51.95  ? 323 GLU A O   1 
ATOM   2264 C  CB  . GLU A 1 323 ? 143.850 128.721 148.311 1.00 51.95  ? 323 GLU A CB  1 
ATOM   2265 C  CG  . GLU A 1 323 ? 145.166 128.871 149.058 1.00 51.95  ? 323 GLU A CG  1 
ATOM   2266 C  CD  . GLU A 1 323 ? 145.686 130.287 149.048 1.00 51.95  ? 323 GLU A CD  1 
ATOM   2267 O  OE1 . GLU A 1 323 ? 144.901 131.213 149.341 1.00 51.95  ? 323 GLU A OE1 1 
ATOM   2268 O  OE2 . GLU A 1 323 ? 146.883 130.470 148.748 1.00 51.95  ? 323 GLU A OE2 1 
ATOM   2269 N  N   . THR A 1 324 ? 143.531 126.904 150.944 1.00 52.35  ? 324 THR A N   1 
ATOM   2270 C  CA  . THR A 1 324 ? 143.839 125.617 151.550 1.00 52.35  ? 324 THR A CA  1 
ATOM   2271 C  C   . THR A 1 324 ? 142.689 125.065 152.377 1.00 52.35  ? 324 THR A C   1 
ATOM   2272 O  O   . THR A 1 324 ? 142.742 123.896 152.774 1.00 52.35  ? 324 THR A O   1 
ATOM   2273 C  CB  . THR A 1 324 ? 145.088 125.730 152.426 1.00 52.35  ? 324 THR A CB  1 
ATOM   2274 O  OG1 . THR A 1 324 ? 145.107 127.010 153.068 1.00 52.35  ? 324 THR A OG1 1 
ATOM   2275 C  CG2 . THR A 1 324 ? 146.345 125.567 151.587 1.00 52.35  ? 324 THR A CG2 1 
ATOM   2276 N  N   . LEU A 1 325 ? 141.667 125.879 152.655 1.00 52.09  ? 325 LEU A N   1 
ATOM   2277 C  CA  . LEU A 1 325 ? 140.533 125.416 153.449 1.00 52.09  ? 325 LEU A CA  1 
ATOM   2278 C  C   . LEU A 1 325 ? 139.757 124.325 152.723 1.00 52.09  ? 325 LEU A C   1 
ATOM   2279 O  O   . LEU A 1 325 ? 139.083 123.507 153.357 1.00 52.09  ? 325 LEU A O   1 
ATOM   2280 C  CB  . LEU A 1 325 ? 139.629 126.596 153.798 1.00 52.09  ? 325 LEU A CB  1 
ATOM   2281 C  CG  . LEU A 1 325 ? 139.999 127.256 155.126 1.00 52.09  ? 325 LEU A CG  1 
ATOM   2282 C  CD1 . LEU A 1 325 ? 139.437 128.658 155.227 1.00 52.09  ? 325 LEU A CD1 1 
ATOM   2283 C  CD2 . LEU A 1 325 ? 139.510 126.405 156.287 1.00 52.09  ? 325 LEU A CD2 1 
ATOM   2284 N  N   . GLY A 1 326 ? 139.838 124.296 151.396 1.00 51.72  ? 326 GLY A N   1 
ATOM   2285 C  CA  . GLY A 1 326 ? 139.301 123.171 150.662 1.00 51.72  ? 326 GLY A CA  1 
ATOM   2286 C  C   . GLY A 1 326 ? 140.147 121.920 150.716 1.00 51.72  ? 326 GLY A C   1 
ATOM   2287 O  O   . GLY A 1 326 ? 139.683 120.854 150.301 1.00 51.72  ? 326 GLY A O   1 
ATOM   2288 N  N   . SER A 1 327 ? 141.374 122.024 151.223 1.00 56.04  ? 327 SER A N   1 
ATOM   2289 C  CA  . SER A 1 327 ? 142.312 120.912 151.268 1.00 56.04  ? 327 SER A CA  1 
ATOM   2290 C  C   . SER A 1 327 ? 142.506 120.350 152.670 1.00 56.04  ? 327 SER A C   1 
ATOM   2291 O  O   . SER A 1 327 ? 143.461 119.599 152.896 1.00 56.04  ? 327 SER A O   1 
ATOM   2292 C  CB  . SER A 1 327 ? 143.662 121.344 150.692 1.00 56.04  ? 327 SER A CB  1 
ATOM   2293 O  OG  . SER A 1 327 ? 144.676 120.411 151.021 1.00 56.04  ? 327 SER A OG  1 
ATOM   2294 N  N   . THR A 1 328 ? 141.633 120.692 153.616 1.00 52.93  ? 328 THR A N   1 
ATOM   2295 C  CA  . THR A 1 328 ? 141.759 120.204 154.989 1.00 52.93  ? 328 THR A CA  1 
ATOM   2296 C  C   . THR A 1 328 ? 141.350 118.740 155.024 1.00 52.93  ? 328 THR A C   1 
ATOM   2297 O  O   . THR A 1 328 ? 140.176 118.402 155.176 1.00 52.93  ? 328 THR A O   1 
ATOM   2298 C  CB  . THR A 1 328 ? 140.906 121.026 155.946 1.00 52.93  ? 328 THR A CB  1 
ATOM   2299 O  OG1 . THR A 1 328 ? 139.525 120.696 155.755 1.00 52.93  ? 328 THR A OG1 1 
ATOM   2300 C  CG2 . THR A 1 328 ? 141.105 122.502 155.700 1.00 52.93  ? 328 THR A CG2 1 
ATOM   2301 N  N   . SER A 1 329 ? 142.334 117.854 154.878 1.00 57.30  ? 329 SER A N   1 
ATOM   2302 C  CA  . SER A 1 329 ? 142.063 116.433 155.037 1.00 57.30  ? 329 SER A CA  1 
ATOM   2303 C  C   . SER A 1 329 ? 141.903 116.037 156.497 1.00 57.30  ? 329 SER A C   1 
ATOM   2304 O  O   . SER A 1 329 ? 141.365 114.960 156.774 1.00 57.30  ? 329 SER A O   1 
ATOM   2305 C  CB  . SER A 1 329 ? 143.174 115.605 154.391 1.00 57.30  ? 329 SER A CB  1 
ATOM   2306 O  OG  . SER A 1 329 ? 142.895 114.219 154.484 1.00 57.30  ? 329 SER A OG  1 
ATOM   2307 N  N   . VAL A 1 330 ? 142.354 116.873 157.428 1.00 54.12  ? 330 VAL A N   1 
ATOM   2308 C  CA  . VAL A 1 330 ? 142.193 116.620 158.854 1.00 54.12  ? 330 VAL A CA  1 
ATOM   2309 C  C   . VAL A 1 330 ? 141.850 117.932 159.550 1.00 54.12  ? 330 VAL A C   1 
ATOM   2310 O  O   . VAL A 1 330 ? 142.270 119.011 159.118 1.00 54.12  ? 330 VAL A O   1 
ATOM   2311 C  CB  . VAL A 1 330 ? 143.448 115.948 159.460 1.00 54.12  ? 330 VAL A CB  1 
ATOM   2312 C  CG1 . VAL A 1 330 ? 144.500 116.967 159.874 1.00 54.12  ? 330 VAL A CG1 1 
ATOM   2313 C  CG2 . VAL A 1 330 ? 143.061 115.077 160.641 1.00 54.12  ? 330 VAL A CG2 1 
ATOM   2314 N  N   . ILE A 1 331 ? 141.021 117.841 160.588 1.00 48.45  ? 331 ILE A N   1 
ATOM   2315 C  CA  . ILE A 1 331 ? 140.687 118.973 161.443 1.00 48.45  ? 331 ILE A CA  1 
ATOM   2316 C  C   . ILE A 1 331 ? 140.765 118.512 162.891 1.00 48.45  ? 331 ILE A C   1 
ATOM   2317 O  O   . ILE A 1 331 ? 140.195 117.475 163.250 1.00 48.45  ? 331 ILE A O   1 
ATOM   2318 C  CB  . ILE A 1 331 ? 139.294 119.555 161.126 1.00 48.45  ? 331 ILE A CB  1 
ATOM   2319 C  CG1 . ILE A 1 331 ? 138.262 118.442 160.928 1.00 48.45  ? 331 ILE A CG1 1 
ATOM   2320 C  CG2 . ILE A 1 331 ? 139.359 120.461 159.906 1.00 48.45  ? 331 ILE A CG2 1 
ATOM   2321 C  CD1 . ILE A 1 331 ? 136.922 118.931 160.422 1.00 48.45  ? 331 ILE A CD1 1 
ATOM   2322 N  N   . CYS A 1 332 ? 141.478 119.269 163.715 1.00 53.25  ? 332 CYS A N   1 
ATOM   2323 C  CA  . CYS A 1 332 ? 141.654 118.947 165.128 1.00 53.25  ? 332 CYS A CA  1 
ATOM   2324 C  C   . CYS A 1 332 ? 140.828 119.946 165.935 1.00 53.25  ? 332 CYS A C   1 
ATOM   2325 O  O   . CYS A 1 332 ? 141.307 121.021 166.294 1.00 53.25  ? 332 CYS A O   1 
ATOM   2326 C  CB  . CYS A 1 332 ? 143.125 118.983 165.519 1.00 53.25  ? 332 CYS A CB  1 
ATOM   2327 S  SG  . CYS A 1 332 ? 144.167 117.837 164.591 1.00 53.25  ? 332 CYS A SG  1 
ATOM   2328 N  N   . THR A 1 333 ? 139.584 119.574 166.221 1.00 51.53  ? 333 THR A N   1 
ATOM   2329 C  CA  . THR A 1 333 ? 138.645 120.419 166.939 1.00 51.53  ? 333 THR A CA  1 
ATOM   2330 C  C   . THR A 1 333 ? 138.630 120.039 168.416 1.00 51.53  ? 333 THR A C   1 
ATOM   2331 O  O   . THR A 1 333 ? 139.372 119.166 168.861 1.00 51.53  ? 333 THR A O   1 
ATOM   2332 C  CB  . THR A 1 333 ? 137.252 120.301 166.324 1.00 51.53  ? 333 THR A CB  1 
ATOM   2333 O  OG1 . THR A 1 333 ? 136.544 119.224 166.950 1.00 51.53  ? 333 THR A OG1 1 
ATOM   2334 C  CG2 . THR A 1 333 ? 137.365 120.027 164.836 1.00 51.53  ? 333 THR A CG2 1 
ATOM   2335 N  N   . ASP A 1 334 ? 137.788 120.721 169.192 1.00 57.36  ? 334 ASP A N   1 
ATOM   2336 C  CA  . ASP A 1 334 ? 137.561 120.363 170.585 1.00 57.36  ? 334 ASP A CA  1 
ATOM   2337 C  C   . ASP A 1 334 ? 136.065 120.277 170.841 1.00 57.36  ? 334 ASP A C   1 
ATOM   2338 O  O   . ASP A 1 334 ? 135.268 120.963 170.198 1.00 57.36  ? 334 ASP A O   1 
ATOM   2339 C  CB  . ASP A 1 334 ? 138.190 121.363 171.571 1.00 57.36  ? 334 ASP A CB  1 
ATOM   2340 C  CG  . ASP A 1 334 ? 137.831 122.801 171.261 1.00 57.36  ? 334 ASP A CG  1 
ATOM   2341 O  OD1 . ASP A 1 334 ? 137.273 123.056 170.176 1.00 57.36  ? 334 ASP A OD1 1 
ATOM   2342 O  OD2 . ASP A 1 334 ? 138.108 123.678 172.106 1.00 57.36  ? 334 ASP A OD2 1 
ATOM   2343 N  N   . LYS A 1 335 ? 135.693 119.421 171.792 1.00 54.89  ? 335 LYS A N   1 
ATOM   2344 C  CA  . LYS A 1 335 ? 134.280 119.197 172.075 1.00 54.89  ? 335 LYS A CA  1 
ATOM   2345 C  C   . LYS A 1 335 ? 133.648 120.404 172.756 1.00 54.89  ? 335 LYS A C   1 
ATOM   2346 O  O   . LYS A 1 335 ? 132.549 120.832 172.384 1.00 54.89  ? 335 LYS A O   1 
ATOM   2347 C  CB  . LYS A 1 335 ? 134.116 117.951 172.935 1.00 54.89  ? 335 LYS A CB  1 
ATOM   2348 C  CG  . LYS A 1 335 ? 132.692 117.671 173.356 1.00 54.89  ? 335 LYS A CG  1 
ATOM   2349 C  CD  . LYS A 1 335 ? 132.681 116.902 174.654 1.00 54.89  ? 335 LYS A CD  1 
ATOM   2350 C  CE  . LYS A 1 335 ? 133.598 117.551 175.669 1.00 54.89  ? 335 LYS A CE  1 
ATOM   2351 N  NZ  . LYS A 1 335 ? 133.479 116.913 177.010 1.00 54.89  ? 335 LYS A NZ  1 
ATOM   2352 N  N   . THR A 1 336 ? 134.319 120.957 173.762 1.00 50.45  ? 336 THR A N   1 
ATOM   2353 C  CA  . THR A 1 336 ? 133.778 122.108 174.470 1.00 50.45  ? 336 THR A CA  1 
ATOM   2354 C  C   . THR A 1 336 ? 133.786 123.328 173.560 1.00 50.45  ? 336 THR A C   1 
ATOM   2355 O  O   . THR A 1 336 ? 134.817 123.677 172.978 1.00 50.45  ? 336 THR A O   1 
ATOM   2356 C  CB  . THR A 1 336 ? 134.587 122.383 175.737 1.00 50.45  ? 336 THR A CB  1 
ATOM   2357 O  OG1 . THR A 1 336 ? 134.703 121.178 176.502 1.00 50.45  ? 336 THR A OG1 1 
ATOM   2358 C  CG2 . THR A 1 336 ? 133.904 123.448 176.582 1.00 50.45  ? 336 THR A CG2 1 
ATOM   2359 N  N   . GLY A 1 337 ? 132.633 123.978 173.440 1.00 55.01  ? 337 GLY A N   1 
ATOM   2360 C  CA  . GLY A 1 337 ? 132.497 125.110 172.547 1.00 55.01  ? 337 GLY A CA  1 
ATOM   2361 C  C   . GLY A 1 337 ? 131.982 124.740 171.171 1.00 55.01  ? 337 GLY A C   1 
ATOM   2362 O  O   . GLY A 1 337 ? 130.893 125.168 170.778 1.00 55.01  ? 337 GLY A O   1 
ATOM   2363 N  N   . THR A 1 338 ? 132.748 123.941 170.426 1.00 54.18  ? 338 THR A N   1 
ATOM   2364 C  CA  . THR A 1 338 ? 132.345 123.587 169.068 1.00 54.18  ? 338 THR A CA  1 
ATOM   2365 C  C   . THR A 1 338 ? 131.293 122.484 169.069 1.00 54.18  ? 338 THR A C   1 
ATOM   2366 O  O   . THR A 1 338 ? 130.178 122.671 168.570 1.00 54.18  ? 338 THR A O   1 
ATOM   2367 C  CB  . THR A 1 338 ? 133.562 123.156 168.247 1.00 54.18  ? 338 THR A CB  1 
ATOM   2368 O  OG1 . THR A 1 338 ? 133.950 121.830 168.623 1.00 54.18  ? 338 THR A OG1 1 
ATOM   2369 C  CG2 . THR A 1 338 ? 134.718 124.097 168.481 1.00 54.18  ? 338 THR A CG2 1 
ATOM   2370 N  N   . LEU A 1 339 ? 131.635 121.324 169.625 1.00 51.08  ? 339 LEU A N   1 
ATOM   2371 C  CA  . LEU A 1 339 ? 130.736 120.181 169.676 1.00 51.08  ? 339 LEU A CA  1 
ATOM   2372 C  C   . LEU A 1 339 ? 129.846 120.191 170.912 1.00 51.08  ? 339 LEU A C   1 
ATOM   2373 O  O   . LEU A 1 339 ? 129.362 119.131 171.323 1.00 51.08  ? 339 LEU A O   1 
ATOM   2374 C  CB  . LEU A 1 339 ? 131.537 118.881 169.618 1.00 51.08  ? 339 LEU A CB  1 
ATOM   2375 C  CG  . LEU A 1 339 ? 132.457 118.711 168.408 1.00 51.08  ? 339 LEU A CG  1 
ATOM   2376 C  CD1 . LEU A 1 339 ? 133.513 117.657 168.687 1.00 51.08  ? 339 LEU A CD1 1 
ATOM   2377 C  CD2 . LEU A 1 339 ? 131.650 118.350 167.177 1.00 51.08  ? 339 LEU A CD2 1 
ATOM   2378 N  N   . THR A 1 340 ? 129.630 121.360 171.515 1.00 58.88  ? 340 THR A N   1 
ATOM   2379 C  CA  . THR A 1 340 ? 128.805 121.484 172.711 1.00 58.88  ? 340 THR A CA  1 
ATOM   2380 C  C   . THR A 1 340 ? 128.422 122.946 172.887 1.00 58.88  ? 340 THR A C   1 
ATOM   2381 O  O   . THR A 1 340 ? 129.297 123.817 172.907 1.00 58.88  ? 340 THR A O   1 
ATOM   2382 C  CB  . THR A 1 340 ? 129.557 120.959 173.947 1.00 58.88  ? 340 THR A CB  1 
ATOM   2383 O  OG1 . THR A 1 340 ? 129.507 119.524 173.955 1.00 58.88  ? 340 THR A OG1 1 
ATOM   2384 C  CG2 . THR A 1 340 ? 128.932 121.471 175.231 1.00 58.88  ? 340 THR A CG2 1 
ATOM   2385 N  N   . GLN A 1 341 ? 127.117 123.209 173.006 1.00 66.99  ? 341 GLN A N   1 
ATOM   2386 C  CA  . GLN A 1 341 ? 126.584 124.559 173.177 1.00 66.99  ? 341 GLN A CA  1 
ATOM   2387 C  C   . GLN A 1 341 ? 126.594 125.030 174.627 1.00 66.99  ? 341 GLN A C   1 
ATOM   2388 O  O   . GLN A 1 341 ? 125.872 125.982 174.957 1.00 66.99  ? 341 GLN A O   1 
ATOM   2389 C  CB  . GLN A 1 341 ? 125.155 124.642 172.623 1.00 66.99  ? 341 GLN A CB  1 
ATOM   2390 C  CG  . GLN A 1 341 ? 124.119 123.814 173.381 1.00 66.99  ? 341 GLN A CG  1 
ATOM   2391 C  CD  . GLN A 1 341 ? 123.963 122.428 172.801 1.00 66.99  ? 341 GLN A CD  1 
ATOM   2392 O  OE1 . GLN A 1 341 ? 124.779 121.998 171.988 1.00 66.99  ? 341 GLN A OE1 1 
ATOM   2393 N  NE2 . GLN A 1 341 ? 122.913 121.724 173.207 1.00 66.99  ? 341 GLN A NE2 1 
ATOM   2394 N  N   . ASN A 1 342 ? 127.394 124.385 175.480 1.00 77.81  ? 342 ASN A N   1 
ATOM   2395 C  CA  . ASN A 1 342 ? 127.424 124.580 176.927 1.00 77.81  ? 342 ASN A CA  1 
ATOM   2396 C  C   . ASN A 1 342 ? 126.048 124.346 177.545 1.00 77.81  ? 342 ASN A C   1 
ATOM   2397 O  O   . ASN A 1 342 ? 125.192 123.715 176.917 1.00 77.81  ? 342 ASN A O   1 
ATOM   2398 C  CB  . ASN A 1 342 ? 127.968 125.971 177.269 1.00 77.81  ? 342 ASN A CB  1 
ATOM   2399 C  CG  . ASN A 1 342 ? 129.396 126.161 176.802 1.00 77.81  ? 342 ASN A CG  1 
ATOM   2400 O  OD1 . ASN A 1 342 ? 130.191 125.226 176.801 1.00 77.81  ? 342 ASN A OD1 1 
ATOM   2401 N  ND2 . ASN A 1 342 ? 129.728 127.382 176.404 1.00 77.81  ? 342 ASN A ND2 1 
ATOM   2402 N  N   . LYS A 1 343 ? 125.839 124.841 178.766 1.00 84.92  ? 343 LYS A N   1 
ATOM   2403 C  CA  . LYS A 1 343 ? 124.567 124.738 179.486 1.00 84.92  ? 343 LYS A CA  1 
ATOM   2404 C  C   . LYS A 1 343 ? 124.106 123.281 179.598 1.00 84.92  ? 343 LYS A C   1 
ATOM   2405 O  O   . LYS A 1 343 ? 123.127 122.860 178.976 1.00 84.92  ? 343 LYS A O   1 
ATOM   2406 C  CB  . LYS A 1 343 ? 123.489 125.601 178.825 1.00 84.92  ? 343 LYS A CB  1 
ATOM   2407 C  CG  . LYS A 1 343 ? 123.954 126.983 178.387 1.00 84.92  ? 343 LYS A CG  1 
ATOM   2408 C  CD  . LYS A 1 343 ? 122.809 127.750 177.728 1.00 84.92  ? 343 LYS A CD  1 
ATOM   2409 C  CE  . LYS A 1 343 ? 123.295 129.024 177.057 1.00 84.92  ? 343 LYS A CE  1 
ATOM   2410 N  NZ  . LYS A 1 343 ? 124.028 129.915 178.000 1.00 84.92  ? 343 LYS A NZ  1 
ATOM   2411 N  N   . MET A 1 344 ? 124.839 122.503 180.398 1.00 83.04  ? 344 MET A N   1 
ATOM   2412 C  CA  . MET A 1 344 ? 124.554 121.078 180.497 1.00 83.04  ? 344 MET A CA  1 
ATOM   2413 C  C   . MET A 1 344 ? 123.253 120.846 181.260 1.00 83.04  ? 344 MET A C   1 
ATOM   2414 O  O   . MET A 1 344 ? 122.696 121.750 181.892 1.00 83.04  ? 344 MET A O   1 
ATOM   2415 C  CB  . MET A 1 344 ? 125.663 120.321 181.230 1.00 83.04  ? 344 MET A CB  1 
ATOM   2416 C  CG  . MET A 1 344 ? 127.015 120.301 180.581 1.00 83.04  ? 344 MET A CG  1 
ATOM   2417 S  SD  . MET A 1 344 ? 127.067 119.486 178.993 1.00 83.04  ? 344 MET A SD  1 
ATOM   2418 C  CE  . MET A 1 344 ? 127.112 120.949 177.957 1.00 83.04  ? 344 MET A CE  1 
ATOM   2419 N  N   . THR A 1 345 ? 122.773 119.604 181.193 1.00 87.49  ? 345 THR A N   1 
ATOM   2420 C  CA  . THR A 1 345 ? 121.639 119.140 181.996 1.00 87.49  ? 345 THR A CA  1 
ATOM   2421 C  C   . THR A 1 345 ? 121.979 117.741 182.503 1.00 87.49  ? 345 THR A C   1 
ATOM   2422 O  O   . THR A 1 345 ? 121.928 116.776 181.737 1.00 87.49  ? 345 THR A O   1 
ATOM   2423 C  CB  . THR A 1 345 ? 120.338 119.118 181.198 1.00 87.49  ? 345 THR A CB  1 
ATOM   2424 O  OG1 . THR A 1 345 ? 120.557 118.476 179.934 1.00 87.49  ? 345 THR A OG1 1 
ATOM   2425 C  CG2 . THR A 1 345 ? 119.801 120.524 180.976 1.00 87.49  ? 345 THR A CG2 1 
ATOM   2426 N  N   . VAL A 1 346 ? 122.305 117.630 183.793 1.00 83.11  ? 346 VAL A N   1 
ATOM   2427 C  CA  . VAL A 1 346 ? 122.620 116.326 184.367 1.00 83.11  ? 346 VAL A CA  1 
ATOM   2428 C  C   . VAL A 1 346 ? 121.380 115.444 184.356 1.00 83.11  ? 346 VAL A C   1 
ATOM   2429 O  O   . VAL A 1 346 ? 120.312 115.829 184.849 1.00 83.11  ? 346 VAL A O   1 
ATOM   2430 C  CB  . VAL A 1 346 ? 123.208 116.490 185.777 1.00 83.11  ? 346 VAL A CB  1 
ATOM   2431 C  CG1 . VAL A 1 346 ? 123.422 115.152 186.422 1.00 83.11  ? 346 VAL A CG1 1 
ATOM   2432 C  CG2 . VAL A 1 346 ? 124.527 117.239 185.727 1.00 83.11  ? 346 VAL A CG2 1 
ATOM   2433 N  N   . VAL A 1 347 ? 121.517 114.253 183.774 1.00 90.88  ? 347 VAL A N   1 
ATOM   2434 C  CA  . VAL A 1 347 ? 120.376 113.376 183.548 1.00 90.88  ? 347 VAL A CA  1 
ATOM   2435 C  C   . VAL A 1 347 ? 120.317 112.202 184.521 1.00 90.88  ? 347 VAL A C   1 
ATOM   2436 O  O   . VAL A 1 347 ? 119.229 111.647 184.735 1.00 90.88  ? 347 VAL A O   1 
ATOM   2437 C  CB  . VAL A 1 347 ? 120.371 112.859 182.094 1.00 90.88  ? 347 VAL A CB  1 
ATOM   2438 C  CG1 . VAL A 1 347 ? 120.098 114.004 181.132 1.00 90.88  ? 347 VAL A CG1 1 
ATOM   2439 C  CG2 . VAL A 1 347 ? 121.693 112.179 181.763 1.00 90.88  ? 347 VAL A CG2 1 
ATOM   2440 N  N   . ASP A 1 348 ? 121.442 111.812 185.116 1.00 99.27  ? 348 ASP A N   1 
ATOM   2441 C  CA  . ASP A 1 348 ? 121.455 110.706 186.060 1.00 99.27  ? 348 ASP A CA  1 
ATOM   2442 C  C   . ASP A 1 348 ? 122.492 110.988 187.135 1.00 99.27  ? 348 ASP A C   1 
ATOM   2443 O  O   . ASP A 1 348 ? 123.375 111.833 186.968 1.00 99.27  ? 348 ASP A O   1 
ATOM   2444 C  CB  . ASP A 1 348 ? 121.742 109.371 185.366 1.00 99.27  ? 348 ASP A CB  1 
ATOM   2445 C  CG  . ASP A 1 348 ? 121.049 108.206 186.041 1.00 99.27  ? 348 ASP A CG  1 
ATOM   2446 O  OD1 . ASP A 1 348 ? 119.800 108.184 186.051 1.00 99.27  ? 348 ASP A OD1 1 
ATOM   2447 O  OD2 . ASP A 1 348 ? 121.751 107.315 186.562 1.00 99.27  ? 348 ASP A OD2 1 
ATOM   2448 N  N   . TYR A 1 349 ? 122.310 110.309 188.267 1.00 111.23 ? 349 TYR A N   1 
ATOM   2449 C  CA  . TYR A 1 349 ? 123.220 110.539 189.413 1.00 111.23 ? 349 TYR A CA  1 
ATOM   2450 C  C   . TYR A 1 349 ? 123.445 109.239 190.159 1.00 111.23 ? 349 TYR A C   1 
ATOM   2451 O  O   . TYR A 1 349 ? 122.639 108.294 190.026 1.00 111.23 ? 349 TYR A O   1 
ATOM   2452 C  CB  . TYR A 1 349 ? 122.621 111.614 190.326 1.00 111.23 ? 349 TYR A CB  1 
ATOM   2453 C  CG  . TYR A 1 349 ? 121.888 111.071 191.545 1.00 111.23 ? 349 TYR A CG  1 
ATOM   2454 C  CD1 . TYR A 1 349 ? 120.645 110.460 191.425 1.00 111.23 ? 349 TYR A CD1 1 
ATOM   2455 C  CD2 . TYR A 1 349 ? 122.442 111.169 192.815 1.00 111.23 ? 349 TYR A CD2 1 
ATOM   2456 C  CE1 . TYR A 1 349 ? 119.979 109.959 192.530 1.00 111.23 ? 349 TYR A CE1 1 
ATOM   2457 C  CE2 . TYR A 1 349 ? 121.784 110.673 193.928 1.00 111.23 ? 349 TYR A CE2 1 
ATOM   2458 C  CZ  . TYR A 1 349 ? 120.549 110.068 193.784 1.00 111.23 ? 349 TYR A CZ  1 
ATOM   2459 O  OH  . TYR A 1 349 ? 119.895 109.582 194.878 1.00 111.23 ? 349 TYR A OH  1 
ATOM   2460 N  N   . TYR A 1 350 ? 124.530 109.180 190.916 1.00 112.50 ? 350 TYR A N   1 
ATOM   2461 C  CA  . TYR A 1 350 ? 124.884 108.032 191.735 1.00 112.50 ? 350 TYR A CA  1 
ATOM   2462 C  C   . TYR A 1 350 ? 124.871 108.437 193.201 1.00 112.50 ? 350 TYR A C   1 
ATOM   2463 O  O   . TYR A 1 350 ? 125.286 109.545 193.550 1.00 112.50 ? 350 TYR A O   1 
ATOM   2464 C  CB  . TYR A 1 350 ? 126.266 107.478 191.352 1.00 112.50 ? 350 TYR A CB  1 
ATOM   2465 C  CG  . TYR A 1 350 ? 127.021 106.831 192.495 1.00 112.50 ? 350 TYR A CG  1 
ATOM   2466 C  CD1 . TYR A 1 350 ? 128.067 107.494 193.126 1.00 112.50 ? 350 TYR A CD1 1 
ATOM   2467 C  CD2 . TYR A 1 350 ? 126.695 105.554 192.935 1.00 112.50 ? 350 TYR A CD2 1 
ATOM   2468 C  CE1 . TYR A 1 350 ? 128.758 106.912 194.168 1.00 112.50 ? 350 TYR A CE1 1 
ATOM   2469 C  CE2 . TYR A 1 350 ? 127.384 104.962 193.978 1.00 112.50 ? 350 TYR A CE2 1 
ATOM   2470 C  CZ  . TYR A 1 350 ? 128.414 105.646 194.589 1.00 112.50 ? 350 TYR A CZ  1 
ATOM   2471 O  OH  . TYR A 1 350 ? 129.104 105.063 195.626 1.00 112.50 ? 350 TYR A OH  1 
ATOM   2472 N  N   . LEU A 1 351 ? 124.377 107.540 194.053 1.00 119.91 ? 351 LEU A N   1 
ATOM   2473 C  CA  . LEU A 1 351 ? 124.417 107.712 195.495 1.00 119.91 ? 351 LEU A CA  1 
ATOM   2474 C  C   . LEU A 1 351 ? 124.975 106.421 196.083 1.00 119.91 ? 351 LEU A C   1 
ATOM   2475 O  O   . LEU A 1 351 ? 124.576 105.325 195.649 1.00 119.91 ? 351 LEU A O   1 
ATOM   2476 C  CB  . LEU A 1 351 ? 123.016 108.017 196.052 1.00 119.91 ? 351 LEU A CB  1 
ATOM   2477 C  CG  . LEU A 1 351 ? 122.572 107.635 197.468 1.00 119.91 ? 351 LEU A CG  1 
ATOM   2478 C  CD1 . LEU A 1 351 ? 123.387 108.345 198.542 1.00 119.91 ? 351 LEU A CD1 1 
ATOM   2479 C  CD2 . LEU A 1 351 ? 121.092 107.915 197.654 1.00 119.91 ? 351 LEU A CD2 1 
ATOM   2480 N  N   . PRO A 1 352 ? 125.914 106.497 197.032 1.00 121.99 ? 352 PRO A N   1 
ATOM   2481 C  CA  . PRO A 1 352 ? 126.433 105.265 197.653 1.00 121.99 ? 352 PRO A CA  1 
ATOM   2482 C  C   . PRO A 1 352 ? 125.370 104.412 198.326 1.00 121.99 ? 352 PRO A C   1 
ATOM   2483 O  O   . PRO A 1 352 ? 125.522 103.185 198.375 1.00 121.99 ? 352 PRO A O   1 
ATOM   2484 C  CB  . PRO A 1 352 ? 127.468 105.786 198.663 1.00 121.99 ? 352 PRO A CB  1 
ATOM   2485 C  CG  . PRO A 1 352 ? 127.266 107.276 198.732 1.00 121.99 ? 352 PRO A CG  1 
ATOM   2486 C  CD  . PRO A 1 352 ? 126.700 107.679 197.416 1.00 121.99 ? 352 PRO A CD  1 
ATOM   2487 N  N   . ASP A 1 353 ? 124.303 105.015 198.859 1.00 128.41 ? 353 ASP A N   1 
ATOM   2488 C  CA  . ASP A 1 353 ? 123.184 104.213 199.346 1.00 128.41 ? 353 ASP A CA  1 
ATOM   2489 C  C   . ASP A 1 353 ? 122.460 103.525 198.193 1.00 128.41 ? 353 ASP A C   1 
ATOM   2490 O  O   . ASP A 1 353 ? 122.130 102.336 198.281 1.00 128.41 ? 353 ASP A O   1 
ATOM   2491 C  CB  . ASP A 1 353 ? 122.219 105.085 200.149 1.00 128.41 ? 353 ASP A CB  1 
ATOM   2492 C  CG  . ASP A 1 353 ? 122.935 105.995 201.133 1.00 128.41 ? 353 ASP A CG  1 
ATOM   2493 O  OD1 . ASP A 1 353 ? 124.158 105.828 201.320 1.00 128.41 ? 353 ASP A OD1 1 
ATOM   2494 O  OD2 . ASP A 1 353 ? 122.274 106.880 201.715 1.00 128.41 ? 353 ASP A OD2 1 
ATOM   2495 N  N   . GLY A 1 354 ? 122.208 104.252 197.105 1.00 124.95 ? 354 GLY A N   1 
ATOM   2496 C  CA  . GLY A 1 354 ? 121.701 103.646 195.888 1.00 124.95 ? 354 GLY A CA  1 
ATOM   2497 C  C   . GLY A 1 354 ? 120.203 103.737 195.672 1.00 124.95 ? 354 GLY A C   1 
ATOM   2498 O  O   . GLY A 1 354 ? 119.432 103.022 196.319 1.00 124.95 ? 354 GLY A O   1 
ATOM   2499 N  N   . THR A 1 355 ? 119.786 104.609 194.753 1.00 120.98 ? 355 THR A N   1 
ATOM   2500 C  CA  . THR A 1 355 ? 118.397 104.701 194.319 1.00 120.98 ? 355 THR A CA  1 
ATOM   2501 C  C   . THR A 1 355 ? 118.357 105.404 192.968 1.00 120.98 ? 355 THR A C   1 
ATOM   2502 O  O   . THR A 1 355 ? 119.394 105.712 192.373 1.00 120.98 ? 355 THR A O   1 
ATOM   2503 C  CB  . THR A 1 355 ? 117.525 105.443 195.339 1.00 120.98 ? 355 THR A CB  1 
ATOM   2504 O  OG1 . THR A 1 355 ? 116.249 105.733 194.755 1.00 120.98 ? 355 THR A OG1 1 
ATOM   2505 C  CG2 . THR A 1 355 ? 118.185 106.743 195.751 1.00 120.98 ? 355 THR A CG2 1 
ATOM   2506 N  N   . LYS A 1 356 ? 117.144 105.657 192.486 1.00 122.74 ? 356 LYS A N   1 
ATOM   2507 C  CA  . LYS A 1 356 ? 116.932 106.380 191.242 1.00 122.74 ? 356 LYS A CA  1 
ATOM   2508 C  C   . LYS A 1 356 ? 116.827 107.876 191.537 1.00 122.74 ? 356 LYS A C   1 
ATOM   2509 O  O   . LYS A 1 356 ? 117.151 108.339 192.634 1.00 122.74 ? 356 LYS A O   1 
ATOM   2510 C  CB  . LYS A 1 356 ? 115.689 105.852 190.530 1.00 122.74 ? 356 LYS A CB  1 
ATOM   2511 C  CG  . LYS A 1 356 ? 114.421 105.955 191.356 1.00 122.74 ? 356 LYS A CG  1 
ATOM   2512 C  CD  . LYS A 1 356 ? 113.202 105.559 190.544 1.00 122.74 ? 356 LYS A CD  1 
ATOM   2513 C  CE  . LYS A 1 356 ? 111.936 105.657 191.375 1.00 122.74 ? 356 LYS A CE  1 
ATOM   2514 N  NZ  . LYS A 1 356 ? 111.742 107.034 191.906 1.00 122.74 ? 356 LYS A NZ  1 
ATOM   2515 N  N   . GLU A 1 357 ? 116.380 108.653 190.552 1.00 126.18 ? 357 GLU A N   1 
ATOM   2516 C  CA  . GLU A 1 357 ? 116.204 110.086 190.749 1.00 126.18 ? 357 GLU A CA  1 
ATOM   2517 C  C   . GLU A 1 357 ? 115.017 110.352 191.669 1.00 126.18 ? 357 GLU A C   1 
ATOM   2518 O  O   . GLU A 1 357 ? 113.928 109.801 191.474 1.00 126.18 ? 357 GLU A O   1 
ATOM   2519 C  CB  . GLU A 1 357 ? 116.010 110.794 189.405 1.00 126.18 ? 357 GLU A CB  1 
ATOM   2520 C  CG  . GLU A 1 357 ? 114.960 110.176 188.480 1.00 126.18 ? 357 GLU A CG  1 
ATOM   2521 C  CD  . GLU A 1 357 ? 115.524 109.089 187.584 1.00 126.18 ? 357 GLU A CD  1 
ATOM   2522 O  OE1 . GLU A 1 357 ? 116.762 108.931 187.546 1.00 126.18 ? 357 GLU A OE1 1 
ATOM   2523 O  OE2 . GLU A 1 357 ? 114.728 108.393 186.919 1.00 126.18 ? 357 GLU A OE2 1 
ATOM   2524 N  N   . ASN A 1 358 ? 115.234 111.187 192.693 1.00 131.29 ? 358 ASN A N   1 
ATOM   2525 C  CA  . ASN A 1 358 ? 114.166 111.511 193.631 1.00 131.29 ? 358 ASN A CA  1 
ATOM   2526 C  C   . ASN A 1 358 ? 114.170 112.982 194.042 1.00 131.29 ? 358 ASN A C   1 
ATOM   2527 O  O   . ASN A 1 358 ? 113.567 113.329 195.065 1.00 131.29 ? 358 ASN A O   1 
ATOM   2528 C  CB  . ASN A 1 358 ? 114.258 110.637 194.890 1.00 131.29 ? 358 ASN A CB  1 
ATOM   2529 C  CG  . ASN A 1 358 ? 114.034 109.165 194.601 1.00 131.29 ? 358 ASN A CG  1 
ATOM   2530 O  OD1 . ASN A 1 358 ? 114.983 108.387 194.509 1.00 131.29 ? 358 ASN A OD1 1 
ATOM   2531 N  ND2 . ASN A 1 358 ? 112.773 108.775 194.455 1.00 131.29 ? 358 ASN A ND2 1 
ATOM   2532 N  N   . PHE A 1 359 ? 114.825 113.854 193.281 1.00 125.50 ? 359 PHE A N   1 
ATOM   2533 C  CA  . PHE A 1 359 ? 114.934 115.258 193.669 1.00 125.50 ? 359 PHE A CA  1 
ATOM   2534 C  C   . PHE A 1 359 ? 113.684 116.103 193.398 1.00 125.50 ? 359 PHE A C   1 
ATOM   2535 O  O   . PHE A 1 359 ? 113.289 116.862 194.292 1.00 125.50 ? 359 PHE A O   1 
ATOM   2536 C  CB  . PHE A 1 359 ? 116.149 115.908 192.995 1.00 125.50 ? 359 PHE A CB  1 
ATOM   2537 C  CG  . PHE A 1 359 ? 117.392 115.072 193.042 1.00 125.50 ? 359 PHE A CG  1 
ATOM   2538 C  CD1 . PHE A 1 359 ? 118.173 115.034 194.184 1.00 125.50 ? 359 PHE A CD1 1 
ATOM   2539 C  CD2 . PHE A 1 359 ? 117.789 114.336 191.939 1.00 125.50 ? 359 PHE A CD2 1 
ATOM   2540 C  CE1 . PHE A 1 359 ? 119.322 114.270 194.230 1.00 125.50 ? 359 PHE A CE1 1 
ATOM   2541 C  CE2 . PHE A 1 359 ? 118.935 113.572 191.978 1.00 125.50 ? 359 PHE A CE2 1 
ATOM   2542 C  CZ  . PHE A 1 359 ? 119.704 113.539 193.125 1.00 125.50 ? 359 PHE A CZ  1 
ATOM   2543 N  N   . PRO A 1 360 ? 113.051 116.058 192.204 1.00 130.31 ? 360 PRO A N   1 
ATOM   2544 C  CA  . PRO A 1 360 ? 111.919 116.979 191.970 1.00 130.31 ? 360 PRO A CA  1 
ATOM   2545 C  C   . PRO A 1 360 ? 110.743 116.780 192.911 1.00 130.31 ? 360 PRO A C   1 
ATOM   2546 O  O   . PRO A 1 360 ? 110.088 117.758 193.291 1.00 130.31 ? 360 PRO A O   1 
ATOM   2547 C  CB  . PRO A 1 360 ? 111.518 116.682 190.519 1.00 130.31 ? 360 PRO A CB  1 
ATOM   2548 C  CG  . PRO A 1 360 ? 112.721 116.132 189.893 1.00 130.31 ? 360 PRO A CG  1 
ATOM   2549 C  CD  . PRO A 1 360 ? 113.386 115.327 190.963 1.00 130.31 ? 360 PRO A CD  1 
ATOM   2550 N  N   . GLU A 1 361 ? 110.456 115.537 193.298 1.00 151.02 ? 361 GLU A N   1 
ATOM   2551 C  CA  . GLU A 1 361 ? 109.274 115.271 194.110 1.00 151.02 ? 361 GLU A CA  1 
ATOM   2552 C  C   . GLU A 1 361 ? 109.507 115.665 195.564 1.00 151.02 ? 361 GLU A C   1 
ATOM   2553 O  O   . GLU A 1 361 ? 108.587 116.157 196.227 1.00 151.02 ? 361 GLU A O   1 
ATOM   2554 C  CB  . GLU A 1 361 ? 108.874 113.791 193.945 1.00 151.02 ? 361 GLU A CB  1 
ATOM   2555 C  CG  . GLU A 1 361 ? 107.611 113.236 194.677 1.00 151.02 ? 361 GLU A CG  1 
ATOM   2556 C  CD  . GLU A 1 361 ? 107.655 113.202 196.203 1.00 151.02 ? 361 GLU A CD  1 
ATOM   2557 O  OE1 . GLU A 1 361 ? 106.570 113.151 196.819 1.00 151.02 ? 361 GLU A OE1 1 
ATOM   2558 O  OE2 . GLU A 1 361 ? 108.757 113.127 196.785 1.00 151.02 ? 361 GLU A OE2 1 
ATOM   2559 N  N   . SER A 1 362 ? 110.730 115.472 196.067 1.00 144.67 ? 362 SER A N   1 
ATOM   2560 C  CA  . SER A 1 362 ? 111.073 115.609 197.480 1.00 144.67 ? 362 SER A CA  1 
ATOM   2561 C  C   . SER A 1 362 ? 110.896 117.033 197.993 1.00 144.67 ? 362 SER A C   1 
ATOM   2562 O  O   . SER A 1 362 ? 111.678 117.923 197.636 1.00 144.67 ? 362 SER A O   1 
ATOM   2563 C  CB  . SER A 1 362 ? 112.517 115.161 197.710 1.00 144.67 ? 362 SER A CB  1 
ATOM   2564 O  OG  . SER A 1 362 ? 112.748 113.884 197.145 1.00 144.67 ? 362 SER A OG  1 
ATOM   2565 N  N   . PRO A 1 363 ? 109.895 117.288 198.844 1.00 155.41 ? 363 PRO A N   1 
ATOM   2566 C  CA  . PRO A 1 363 ? 109.734 118.635 199.406 1.00 155.41 ? 363 PRO A CA  1 
ATOM   2567 C  C   . PRO A 1 363 ? 110.758 118.931 200.491 1.00 155.41 ? 363 PRO A C   1 
ATOM   2568 O  O   . PRO A 1 363 ? 111.333 120.023 200.542 1.00 155.41 ? 363 PRO A O   1 
ATOM   2569 C  CB  . PRO A 1 363 ? 108.305 118.619 199.972 1.00 155.41 ? 363 PRO A CB  1 
ATOM   2570 C  CG  . PRO A 1 363 ? 107.738 117.240 199.652 1.00 155.41 ? 363 PRO A CG  1 
ATOM   2571 C  CD  . PRO A 1 363 ? 108.903 116.349 199.389 1.00 155.41 ? 363 PRO A CD  1 
ATOM   2572 N  N   . GLU A 1 364 ? 110.991 117.954 201.362 1.00 156.39 ? 364 GLU A N   1 
ATOM   2573 C  CA  . GLU A 1 364 ? 111.914 118.094 202.477 1.00 156.39 ? 364 GLU A CA  1 
ATOM   2574 C  C   . GLU A 1 364 ? 113.315 117.670 202.041 1.00 156.39 ? 364 GLU A C   1 
ATOM   2575 O  O   . GLU A 1 364 ? 113.605 117.519 200.851 1.00 156.39 ? 364 GLU A O   1 
ATOM   2576 C  CB  . GLU A 1 364 ? 111.421 117.287 203.677 1.00 156.39 ? 364 GLU A CB  1 
ATOM   2577 C  CG  . GLU A 1 364 ? 109.921 117.364 203.906 1.00 156.39 ? 364 GLU A CG  1 
ATOM   2578 C  CD  . GLU A 1 364 ? 109.185 116.159 203.355 1.00 156.39 ? 364 GLU A CD  1 
ATOM   2579 O  OE1 . GLU A 1 364 ? 109.843 115.282 202.757 1.00 156.39 ? 364 GLU A OE1 1 
ATOM   2580 O  OE2 . GLU A 1 364 ? 107.949 116.088 203.519 1.00 156.39 ? 364 GLU A OE2 1 
ATOM   2581 N  N   . ASN A 1 365 ? 114.206 117.483 203.017 1.00 151.15 ? 365 ASN A N   1 
ATOM   2582 C  CA  . ASN A 1 365 ? 115.584 117.102 202.728 1.00 151.15 ? 365 ASN A CA  1 
ATOM   2583 C  C   . ASN A 1 365 ? 115.703 115.695 202.156 1.00 151.15 ? 365 ASN A C   1 
ATOM   2584 O  O   . ASN A 1 365 ? 116.726 115.386 201.532 1.00 151.15 ? 365 ASN A O   1 
ATOM   2585 C  CB  . ASN A 1 365 ? 116.428 117.221 203.997 1.00 151.15 ? 365 ASN A CB  1 
ATOM   2586 C  CG  . ASN A 1 365 ? 115.860 116.418 205.151 1.00 151.15 ? 365 ASN A CG  1 
ATOM   2587 O  OD1 . ASN A 1 365 ? 114.995 116.892 205.886 1.00 151.15 ? 365 ASN A OD1 1 
ATOM   2588 N  ND2 . ASN A 1 365 ? 116.348 115.194 205.317 1.00 151.15 ? 365 ASN A ND2 1 
ATOM   2589 N  N   . TRP A 1 366 ? 114.699 114.847 202.363 1.00 148.00 ? 366 TRP A N   1 
ATOM   2590 C  CA  . TRP A 1 366 ? 114.634 113.460 201.853 1.00 148.00 ? 366 TRP A CA  1 
ATOM   2591 C  C   . TRP A 1 366 ? 115.810 112.683 202.455 1.00 148.00 ? 366 TRP A C   1 
ATOM   2592 O  O   . TRP A 1 366 ? 116.081 112.810 203.659 1.00 148.00 ? 366 TRP A O   1 
ATOM   2593 C  CB  . TRP A 1 366 ? 114.572 113.460 200.335 1.00 148.00 ? 366 TRP A CB  1 
ATOM   2594 C  CG  . TRP A 1 366 ? 113.609 112.466 199.760 1.00 148.00 ? 366 TRP A CG  1 
ATOM   2595 C  CD1 . TRP A 1 366 ? 113.916 111.388 198.982 1.00 148.00 ? 366 TRP A CD1 1 
ATOM   2596 C  CD2 . TRP A 1 366 ? 112.183 112.466 199.900 1.00 148.00 ? 366 TRP A CD2 1 
ATOM   2597 N  NE1 . TRP A 1 366 ? 112.772 110.712 198.636 1.00 148.00 ? 366 TRP A NE1 1 
ATOM   2598 C  CE2 . TRP A 1 366 ? 111.694 111.354 199.186 1.00 148.00 ? 366 TRP A CE2 1 
ATOM   2599 C  CE3 . TRP A 1 366 ? 111.272 113.296 200.561 1.00 148.00 ? 366 TRP A CE3 1 
ATOM   2600 C  CZ2 . TRP A 1 366 ? 110.336 111.050 199.116 1.00 148.00 ? 366 TRP A CZ2 1 
ATOM   2601 C  CZ3 . TRP A 1 366 ? 109.924 112.993 200.490 1.00 148.00 ? 366 TRP A CZ3 1 
ATOM   2602 C  CH2 . TRP A 1 366 ? 109.469 111.879 199.773 1.00 148.00 ? 366 TRP A CH2 1 
ATOM   2603 N  N   . SER A 1 367 ? 116.514 111.878 201.662 1.00 144.04 ? 367 SER A N   1 
ATOM   2604 C  CA  . SER A 1 367 ? 117.646 111.118 202.168 1.00 144.04 ? 367 SER A CA  1 
ATOM   2605 C  C   . SER A 1 367 ? 118.828 112.041 202.456 1.00 144.04 ? 367 SER A C   1 
ATOM   2606 O  O   . SER A 1 367 ? 118.937 113.146 201.918 1.00 144.04 ? 367 SER A O   1 
ATOM   2607 C  CB  . SER A 1 367 ? 118.056 110.034 201.171 1.00 144.04 ? 367 SER A CB  1 
ATOM   2608 O  OG  . SER A 1 367 ? 118.587 110.603 199.987 1.00 144.04 ? 367 SER A OG  1 
ATOM   2609 N  N   . GLU A 1 368 ? 119.720 111.568 203.331 1.00 141.87 ? 368 GLU A N   1 
ATOM   2610 C  CA  . GLU A 1 368 ? 120.865 112.379 203.735 1.00 141.87 ? 368 GLU A CA  1 
ATOM   2611 C  C   . GLU A 1 368 ? 121.854 112.566 202.588 1.00 141.87 ? 368 GLU A C   1 
ATOM   2612 O  O   . GLU A 1 368 ? 122.437 113.647 202.437 1.00 141.87 ? 368 GLU A O   1 
ATOM   2613 C  CB  . GLU A 1 368 ? 121.547 111.762 204.960 1.00 141.87 ? 368 GLU A CB  1 
ATOM   2614 C  CG  . GLU A 1 368 ? 122.069 110.343 204.777 1.00 141.87 ? 368 GLU A CG  1 
ATOM   2615 C  CD  . GLU A 1 368 ? 121.008 109.289 205.031 1.00 141.87 ? 368 GLU A CD  1 
ATOM   2616 O  OE1 . GLU A 1 368 ? 120.120 109.528 205.875 1.00 141.87 ? 368 GLU A OE1 1 
ATOM   2617 O  OE2 . GLU A 1 368 ? 121.062 108.222 204.383 1.00 141.87 ? 368 GLU A OE2 1 
ATOM   2618 N  N   . GLY A 1 369 ? 122.049 111.535 201.764 1.00 134.88 ? 369 GLY A N   1 
ATOM   2619 C  CA  . GLY A 1 369 ? 122.954 111.670 200.634 1.00 134.88 ? 369 GLY A CA  1 
ATOM   2620 C  C   . GLY A 1 369 ? 122.469 112.689 199.622 1.00 134.88 ? 369 GLY A C   1 
ATOM   2621 O  O   . GLY A 1 369 ? 123.249 113.512 199.133 1.00 134.88 ? 369 GLY A O   1 
ATOM   2622 N  N   . GLU A 1 370 ? 121.169 112.662 199.314 1.00 132.46 ? 370 GLU A N   1 
ATOM   2623 C  CA  . GLU A 1 370 ? 120.603 113.603 198.353 1.00 132.46 ? 370 GLU A CA  1 
ATOM   2624 C  C   . GLU A 1 370 ? 120.718 115.039 198.852 1.00 132.46 ? 370 GLU A C   1 
ATOM   2625 O  O   . GLU A 1 370 ? 121.119 115.936 198.101 1.00 132.46 ? 370 GLU A O   1 
ATOM   2626 C  CB  . GLU A 1 370 ? 119.145 113.237 198.066 1.00 132.46 ? 370 GLU A CB  1 
ATOM   2627 C  CG  . GLU A 1 370 ? 118.252 114.415 197.708 1.00 132.46 ? 370 GLU A CG  1 
ATOM   2628 C  CD  . GLU A 1 370 ? 116.788 114.033 197.626 1.00 132.46 ? 370 GLU A CD  1 
ATOM   2629 O  OE1 . GLU A 1 370 ? 116.489 112.821 197.596 1.00 132.46 ? 370 GLU A OE1 1 
ATOM   2630 O  OE2 . GLU A 1 370 ? 115.936 114.946 197.589 1.00 132.46 ? 370 GLU A OE2 1 
ATOM   2631 N  N   . ARG A 1 371 ? 120.391 115.275 200.128 1.00 129.09 ? 371 ARG A N   1 
ATOM   2632 C  CA  . ARG A 1 371 ? 120.456 116.637 200.647 1.00 129.09 ? 371 ARG A CA  1 
ATOM   2633 C  C   . ARG A 1 371 ? 121.897 117.129 200.734 1.00 129.09 ? 371 ARG A C   1 
ATOM   2634 O  O   . ARG A 1 371 ? 122.173 118.285 200.397 1.00 129.09 ? 371 ARG A O   1 
ATOM   2635 C  CB  . ARG A 1 371 ? 119.751 116.744 202.007 1.00 129.09 ? 371 ARG A CB  1 
ATOM   2636 C  CG  . ARG A 1 371 ? 120.336 115.903 203.127 1.00 129.09 ? 371 ARG A CG  1 
ATOM   2637 C  CD  . ARG A 1 371 ? 119.894 116.364 204.508 1.00 129.09 ? 371 ARG A CD  1 
ATOM   2638 N  NE  . ARG A 1 371 ? 120.757 117.407 205.049 1.00 129.09 ? 371 ARG A NE  1 
ATOM   2639 C  CZ  . ARG A 1 371 ? 120.357 118.638 205.335 1.00 129.09 ? 371 ARG A CZ  1 
ATOM   2640 N  NH1 . ARG A 1 371 ? 119.105 119.021 205.141 1.00 129.09 ? 371 ARG A NH1 1 
ATOM   2641 N  NH2 . ARG A 1 371 ? 121.235 119.509 205.823 1.00 129.09 ? 371 ARG A NH2 1 
ATOM   2642 N  N   . ARG A 1 372 ? 122.833 116.267 201.150 1.00 124.72 ? 372 ARG A N   1 
ATOM   2643 C  CA  . ARG A 1 372 ? 124.231 116.685 201.208 1.00 124.72 ? 372 ARG A CA  1 
ATOM   2644 C  C   . ARG A 1 372 ? 124.765 117.003 199.817 1.00 124.72 ? 372 ARG A C   1 
ATOM   2645 O  O   . ARG A 1 372 ? 125.471 118.003 199.629 1.00 124.72 ? 372 ARG A O   1 
ATOM   2646 C  CB  . ARG A 1 372 ? 125.085 115.608 201.879 1.00 124.72 ? 372 ARG A CB  1 
ATOM   2647 C  CG  . ARG A 1 372 ? 124.861 115.460 203.381 1.00 124.72 ? 372 ARG A CG  1 
ATOM   2648 C  CD  . ARG A 1 372 ? 124.659 116.799 204.069 1.00 124.72 ? 372 ARG A CD  1 
ATOM   2649 N  NE  . ARG A 1 372 ? 125.390 116.877 205.328 1.00 124.72 ? 372 ARG A NE  1 
ATOM   2650 C  CZ  . ARG A 1 372 ? 124.952 116.387 206.480 1.00 124.72 ? 372 ARG A CZ  1 
ATOM   2651 N  NH1 . ARG A 1 372 ? 123.782 115.775 206.572 1.00 124.72 ? 372 ARG A NH1 1 
ATOM   2652 N  NH2 . ARG A 1 372 ? 125.706 116.515 207.568 1.00 124.72 ? 372 ARG A NH2 1 
ATOM   2653 N  N   . LEU A 1 373 ? 124.413 116.174 198.827 1.00 119.88 ? 373 LEU A N   1 
ATOM   2654 C  CA  . LEU A 1 373 ? 124.827 116.426 197.452 1.00 119.88 ? 373 LEU A CA  1 
ATOM   2655 C  C   . LEU A 1 373 ? 124.247 117.737 196.935 1.00 119.88 ? 373 LEU A C   1 
ATOM   2656 O  O   . LEU A 1 373 ? 124.944 118.510 196.270 1.00 119.88 ? 373 LEU A O   1 
ATOM   2657 C  CB  . LEU A 1 373 ? 124.411 115.243 196.570 1.00 119.88 ? 373 LEU A CB  1 
ATOM   2658 C  CG  . LEU A 1 373 ? 124.541 115.209 195.043 1.00 119.88 ? 373 LEU A CG  1 
ATOM   2659 C  CD1 . LEU A 1 373 ? 124.659 113.761 194.613 1.00 119.88 ? 373 LEU A CD1 1 
ATOM   2660 C  CD2 . LEU A 1 373 ? 123.352 115.840 194.326 1.00 119.88 ? 373 LEU A CD2 1 
ATOM   2661 N  N   . ILE A 1 374 ? 122.977 118.009 197.244 1.00 122.92 ? 374 ILE A N   1 
ATOM   2662 C  CA  . ILE A 1 374 ? 122.345 119.239 196.775 1.00 122.92 ? 374 ILE A CA  1 
ATOM   2663 C  C   . ILE A 1 374 ? 123.001 120.463 197.406 1.00 122.92 ? 374 ILE A C   1 
ATOM   2664 O  O   . ILE A 1 374 ? 123.299 121.446 196.713 1.00 122.92 ? 374 ILE A O   1 
ATOM   2665 C  CB  . ILE A 1 374 ? 120.830 119.193 197.048 1.00 122.92 ? 374 ILE A CB  1 
ATOM   2666 C  CG1 . ILE A 1 374 ? 120.139 118.258 196.053 1.00 122.92 ? 374 ILE A CG1 1 
ATOM   2667 C  CG2 . ILE A 1 374 ? 120.220 120.583 196.973 1.00 122.92 ? 374 ILE A CG2 1 
ATOM   2668 C  CD1 . ILE A 1 374 ? 118.733 117.876 196.453 1.00 122.92 ? 374 ILE A CD1 1 
ATOM   2669 N  N   . HIS A 1 375 ? 123.246 120.425 198.720 1.00 124.55 ? 375 HIS A N   1 
ATOM   2670 C  CA  . HIS A 1 375 ? 123.865 121.577 199.375 1.00 124.55 ? 375 HIS A CA  1 
ATOM   2671 C  C   . HIS A 1 375 ? 125.290 121.810 198.890 1.00 124.55 ? 375 HIS A C   1 
ATOM   2672 O  O   . HIS A 1 375 ? 125.692 122.961 198.696 1.00 124.55 ? 375 HIS A O   1 
ATOM   2673 C  CB  . HIS A 1 375 ? 123.832 121.454 200.903 1.00 124.55 ? 375 HIS A CB  1 
ATOM   2674 C  CG  . HIS A 1 375 ? 122.527 120.974 201.458 1.00 124.55 ? 375 HIS A CG  1 
ATOM   2675 N  ND1 . HIS A 1 375 ? 121.332 121.104 200.781 1.00 124.55 ? 375 HIS A ND1 1 
ATOM   2676 C  CD2 . HIS A 1 375 ? 122.228 120.373 202.633 1.00 124.55 ? 375 HIS A CD2 1 
ATOM   2677 C  CE1 . HIS A 1 375 ? 120.356 120.598 201.512 1.00 124.55 ? 375 HIS A CE1 1 
ATOM   2678 N  NE2 . HIS A 1 375 ? 120.873 120.147 202.640 1.00 124.55 ? 375 HIS A NE2 1 
ATOM   2679 N  N   . ILE A 1 376 ? 126.074 120.746 198.683 1.00 122.19 ? 376 ILE A N   1 
ATOM   2680 C  CA  . ILE A 1 376 ? 127.428 120.996 198.188 1.00 122.19 ? 376 ILE A CA  1 
ATOM   2681 C  C   . ILE A 1 376 ? 127.395 121.462 196.734 1.00 122.19 ? 376 ILE A C   1 
ATOM   2682 O  O   . ILE A 1 376 ? 128.206 122.306 196.330 1.00 122.19 ? 376 ILE A O   1 
ATOM   2683 C  CB  . ILE A 1 376 ? 128.353 119.776 198.382 1.00 122.19 ? 376 ILE A CB  1 
ATOM   2684 C  CG1 . ILE A 1 376 ? 129.774 120.143 197.953 1.00 122.19 ? 376 ILE A CG1 1 
ATOM   2685 C  CG2 . ILE A 1 376 ? 127.880 118.572 197.595 1.00 122.19 ? 376 ILE A CG2 1 
ATOM   2686 C  CD1 . ILE A 1 376 ? 130.806 119.152 198.330 1.00 122.19 ? 376 ILE A CD1 1 
ATOM   2687 N  N   . ALA A 1 377 ? 126.448 120.958 195.935 1.00 116.02 ? 377 ALA A N   1 
ATOM   2688 C  CA  . ALA A 1 377 ? 126.319 121.410 194.556 1.00 116.02 ? 377 ALA A CA  1 
ATOM   2689 C  C   . ALA A 1 377 ? 125.967 122.889 194.492 1.00 116.02 ? 377 ALA A C   1 
ATOM   2690 O  O   . ALA A 1 377 ? 126.482 123.622 193.641 1.00 116.02 ? 377 ALA A O   1 
ATOM   2691 C  CB  . ALA A 1 377 ? 125.263 120.573 193.836 1.00 116.02 ? 377 ALA A CB  1 
ATOM   2692 N  N   . VAL A 1 378 ? 125.087 123.344 195.385 1.00 123.29 ? 378 VAL A N   1 
ATOM   2693 C  CA  . VAL A 1 378 ? 124.736 124.761 195.422 1.00 123.29 ? 378 VAL A CA  1 
ATOM   2694 C  C   . VAL A 1 378 ? 125.897 125.594 195.960 1.00 123.29 ? 378 VAL A C   1 
ATOM   2695 O  O   . VAL A 1 378 ? 126.216 126.659 195.416 1.00 123.29 ? 378 VAL A O   1 
ATOM   2696 C  CB  . VAL A 1 378 ? 123.451 124.967 196.246 1.00 123.29 ? 378 VAL A CB  1 
ATOM   2697 C  CG1 . VAL A 1 378 ? 123.177 126.445 196.455 1.00 123.29 ? 378 VAL A CG1 1 
ATOM   2698 C  CG2 . VAL A 1 378 ? 122.270 124.309 195.551 1.00 123.29 ? 378 VAL A CG2 1 
ATOM   2699 N  N   . LEU A 1 379 ? 126.559 125.122 197.021 1.00 125.76 ? 379 LEU A N   1 
ATOM   2700 C  CA  . LEU A 1 379 ? 127.555 125.942 197.704 1.00 125.76 ? 379 LEU A CA  1 
ATOM   2701 C  C   . LEU A 1 379 ? 128.831 126.086 196.884 1.00 125.76 ? 379 LEU A C   1 
ATOM   2702 O  O   . LEU A 1 379 ? 129.380 127.188 196.773 1.00 125.76 ? 379 LEU A O   1 
ATOM   2703 C  CB  . LEU A 1 379 ? 127.864 125.347 199.078 1.00 125.76 ? 379 LEU A CB  1 
ATOM   2704 C  CG  . LEU A 1 379 ? 127.241 126.075 200.271 1.00 125.76 ? 379 LEU A CG  1 
ATOM   2705 C  CD1 . LEU A 1 379 ? 127.722 127.515 200.335 1.00 125.76 ? 379 LEU A CD1 1 
ATOM   2706 C  CD2 . LEU A 1 379 ? 125.722 126.016 200.203 1.00 125.76 ? 379 LEU A CD2 1 
ATOM   2707 N  N   . CYS A 1 380 ? 129.322 124.989 196.301 1.00 127.09 ? 380 CYS A N   1 
ATOM   2708 C  CA  . CYS A 1 380 ? 130.517 125.062 195.468 1.00 127.09 ? 380 CYS A CA  1 
ATOM   2709 C  C   . CYS A 1 380 ? 130.258 125.738 194.129 1.00 127.09 ? 380 CYS A C   1 
ATOM   2710 O  O   . CYS A 1 380 ? 131.215 126.023 193.401 1.00 127.09 ? 380 CYS A O   1 
ATOM   2711 C  CB  . CYS A 1 380 ? 131.086 123.661 195.239 1.00 127.09 ? 380 CYS A CB  1 
ATOM   2712 S  SG  . CYS A 1 380 ? 131.799 122.902 196.715 1.00 127.09 ? 380 CYS A SG  1 
ATOM   2713 N  N   . ASN A 1 381 ? 128.998 125.996 193.794 1.00 118.50 ? 381 ASN A N   1 
ATOM   2714 C  CA  . ASN A 1 381 ? 128.639 126.657 192.546 1.00 118.50 ? 381 ASN A CA  1 
ATOM   2715 C  C   . ASN A 1 381 ? 129.025 128.129 192.623 1.00 118.50 ? 381 ASN A C   1 
ATOM   2716 O  O   . ASN A 1 381 ? 128.423 128.897 193.381 1.00 118.50 ? 381 ASN A O   1 
ATOM   2717 C  CB  . ASN A 1 381 ? 127.144 126.494 192.298 1.00 118.50 ? 381 ASN A CB  1 
ATOM   2718 C  CG  . ASN A 1 381 ? 126.767 126.690 190.854 1.00 118.50 ? 381 ASN A CG  1 
ATOM   2719 O  OD1 . ASN A 1 381 ? 127.036 127.733 190.259 1.00 118.50 ? 381 ASN A OD1 1 
ATOM   2720 N  ND2 . ASN A 1 381 ? 126.139 125.677 190.275 1.00 118.50 ? 381 ASN A ND2 1 
ATOM   2721 N  N   . ASP A 1 382 ? 130.033 128.526 191.844 1.00 115.74 ? 382 ASP A N   1 
ATOM   2722 C  CA  . ASP A 1 382 ? 130.430 129.930 191.817 1.00 115.74 ? 382 ASP A CA  1 
ATOM   2723 C  C   . ASP A 1 382 ? 129.385 130.785 191.112 1.00 115.74 ? 382 ASP A C   1 
ATOM   2724 O  O   . ASP A 1 382 ? 129.167 131.944 191.486 1.00 115.74 ? 382 ASP A O   1 
ATOM   2725 C  CB  . ASP A 1 382 ? 131.794 130.079 191.141 1.00 115.74 ? 382 ASP A CB  1 
ATOM   2726 C  CG  . ASP A 1 382 ? 131.899 129.285 189.853 1.00 115.74 ? 382 ASP A CG  1 
ATOM   2727 O  OD1 . ASP A 1 382 ? 131.226 129.652 188.867 1.00 115.74 ? 382 ASP A OD1 1 
ATOM   2728 O  OD2 . ASP A 1 382 ? 132.658 128.294 189.827 1.00 115.74 ? 382 ASP A OD2 1 
ATOM   2729 N  N   . SER A 1 383 ? 128.730 130.234 190.094 1.00 116.14 ? 383 SER A N   1 
ATOM   2730 C  CA  . SER A 1 383 ? 127.752 130.977 189.318 1.00 116.14 ? 383 SER A CA  1 
ATOM   2731 C  C   . SER A 1 383 ? 126.387 130.951 190.003 1.00 116.14 ? 383 SER A C   1 
ATOM   2732 O  O   . SER A 1 383 ? 126.211 130.397 191.092 1.00 116.14 ? 383 SER A O   1 
ATOM   2733 C  CB  . SER A 1 383 ? 127.659 130.412 187.903 1.00 116.14 ? 383 SER A CB  1 
ATOM   2734 O  OG  . SER A 1 383 ? 126.671 131.091 187.147 1.00 116.14 ? 383 SER A OG  1 
ATOM   2735 N  N   . ASN A 1 384 ? 125.407 131.565 189.346 1.00 123.31 ? 384 ASN A N   1 
ATOM   2736 C  CA  . ASN A 1 384 ? 124.034 131.593 189.826 1.00 123.31 ? 384 ASN A CA  1 
ATOM   2737 C  C   . ASN A 1 384 ? 123.116 131.815 188.634 1.00 123.31 ? 384 ASN A C   1 
ATOM   2738 O  O   . ASN A 1 384 ? 123.549 132.265 187.570 1.00 123.31 ? 384 ASN A O   1 
ATOM   2739 C  CB  . ASN A 1 384 ? 123.828 132.683 190.886 1.00 123.31 ? 384 ASN A CB  1 
ATOM   2740 C  CG  . ASN A 1 384 ? 122.592 132.450 191.732 1.00 123.31 ? 384 ASN A CG  1 
ATOM   2741 O  OD1 . ASN A 1 384 ? 121.925 131.422 191.608 1.00 123.31 ? 384 ASN A OD1 1 
ATOM   2742 N  ND2 . ASN A 1 384 ? 122.280 133.405 192.600 1.00 123.31 ? 384 ASN A ND2 1 
ATOM   2743 N  N   . ILE A 1 385 ? 121.838 131.482 188.819 1.00 132.97 ? 385 ILE A N   1 
ATOM   2744 C  CA  . ILE A 1 385 ? 120.880 131.614 187.725 1.00 132.97 ? 385 ILE A CA  1 
ATOM   2745 C  C   . ILE A 1 385 ? 120.579 133.084 187.443 1.00 132.97 ? 385 ILE A C   1 
ATOM   2746 O  O   . ILE A 1 385 ? 120.390 133.473 186.284 1.00 132.97 ? 385 ILE A O   1 
ATOM   2747 C  CB  . ILE A 1 385 ? 119.605 130.797 188.023 1.00 132.97 ? 385 ILE A CB  1 
ATOM   2748 C  CG1 . ILE A 1 385 ? 118.678 130.769 186.804 1.00 132.97 ? 385 ILE A CG1 1 
ATOM   2749 C  CG2 . ILE A 1 385 ? 118.873 131.312 189.256 1.00 132.97 ? 385 ILE A CG2 1 
ATOM   2750 C  CD1 . ILE A 1 385 ? 119.345 130.278 185.541 1.00 132.97 ? 385 ILE A CD1 1 
ATOM   2751 N  N   . ASN A 1 386 ? 120.575 133.924 188.487 1.00 142.49 ? 386 ASN A N   1 
ATOM   2752 C  CA  . ASN A 1 386 ? 120.156 135.324 188.420 1.00 142.49 ? 386 ASN A CA  1 
ATOM   2753 C  C   . ASN A 1 386 ? 118.802 135.462 187.735 1.00 142.49 ? 386 ASN A C   1 
ATOM   2754 O  O   . ASN A 1 386 ? 117.877 134.691 188.014 1.00 142.49 ? 386 ASN A O   1 
ATOM   2755 C  CB  . ASN A 1 386 ? 121.203 136.180 187.698 1.00 142.49 ? 386 ASN A CB  1 
ATOM   2756 C  CG  . ASN A 1 386 ? 122.599 135.980 188.247 1.00 142.49 ? 386 ASN A CG  1 
ATOM   2757 O  OD1 . ASN A 1 386 ? 122.807 135.197 189.171 1.00 142.49 ? 386 ASN A OD1 1 
ATOM   2758 N  ND2 . ASN A 1 386 ? 123.566 136.692 187.681 1.00 142.49 ? 386 ASN A ND2 1 
ATOM   2759 N  N   . SER A 1 387 ? 118.675 136.442 186.845 1.00 152.77 ? 387 SER A N   1 
ATOM   2760 C  CA  . SER A 1 387 ? 117.505 136.516 185.986 1.00 152.77 ? 387 SER A CA  1 
ATOM   2761 C  C   . SER A 1 387 ? 117.519 135.359 184.994 1.00 152.77 ? 387 SER A C   1 
ATOM   2762 O  O   . SER A 1 387 ? 118.579 134.875 184.587 1.00 152.77 ? 387 SER A O   1 
ATOM   2763 C  CB  . SER A 1 387 ? 117.467 137.851 185.243 1.00 152.77 ? 387 SER A CB  1 
ATOM   2764 O  OG  . SER A 1 387 ? 118.653 138.051 184.494 1.00 152.77 ? 387 SER A OG  1 
ATOM   2765 N  N   . GLU A 1 388 ? 116.324 134.907 184.617 1.00 161.14 ? 388 GLU A N   1 
ATOM   2766 C  CA  . GLU A 1 388 ? 116.205 133.753 183.736 1.00 161.14 ? 388 GLU A CA  1 
ATOM   2767 C  C   . GLU A 1 388 ? 116.787 134.058 182.360 1.00 161.14 ? 388 GLU A C   1 
ATOM   2768 O  O   . GLU A 1 388 ? 116.556 135.128 181.790 1.00 161.14 ? 388 GLU A O   1 
ATOM   2769 C  CB  . GLU A 1 388 ? 114.740 133.333 183.612 1.00 161.14 ? 388 GLU A CB  1 
ATOM   2770 C  CG  . GLU A 1 388 ? 113.965 133.407 184.918 1.00 161.14 ? 388 GLU A CG  1 
ATOM   2771 C  CD  . GLU A 1 388 ? 114.559 132.527 186.001 1.00 161.14 ? 388 GLU A CD  1 
ATOM   2772 O  OE1 . GLU A 1 388 ? 114.905 131.364 185.702 1.00 161.14 ? 388 GLU A OE1 1 
ATOM   2773 O  OE2 . GLU A 1 388 ? 114.682 132.998 187.151 1.00 161.14 ? 388 GLU A OE2 1 
ATOM   2774 N  N   . GLY A 1 389 ? 117.549 133.104 181.829 1.00 165.53 ? 389 GLY A N   1 
ATOM   2775 C  CA  . GLY A 1 389 ? 118.221 133.288 180.560 1.00 165.53 ? 389 GLY A CA  1 
ATOM   2776 C  C   . GLY A 1 389 ? 119.546 134.012 180.630 1.00 165.53 ? 389 GLY A C   1 
ATOM   2777 O  O   . GLY A 1 389 ? 120.094 134.367 179.580 1.00 165.53 ? 389 GLY A O   1 
ATOM   2778 N  N   . LYS A 1 390 ? 120.082 134.242 181.827 1.00 155.41 ? 390 LYS A N   1 
ATOM   2779 C  CA  . LYS A 1 390 ? 121.341 134.959 182.013 1.00 155.41 ? 390 LYS A CA  1 
ATOM   2780 C  C   . LYS A 1 390 ? 122.310 134.057 182.766 1.00 155.41 ? 390 LYS A C   1 
ATOM   2781 O  O   . LYS A 1 390 ? 122.165 133.855 183.976 1.00 155.41 ? 390 LYS A O   1 
ATOM   2782 C  CB  . LYS A 1 390 ? 121.116 136.270 182.764 1.00 155.41 ? 390 LYS A CB  1 
ATOM   2783 C  CG  . LYS A 1 390 ? 122.336 137.173 182.820 1.00 155.41 ? 390 LYS A CG  1 
ATOM   2784 C  CD  . LYS A 1 390 ? 122.526 137.931 181.518 1.00 155.41 ? 390 LYS A CD  1 
ATOM   2785 C  CE  . LYS A 1 390 ? 123.613 138.985 181.650 1.00 155.41 ? 390 LYS A CE  1 
ATOM   2786 N  NZ  . LYS A 1 390 ? 123.703 139.845 180.438 1.00 155.41 ? 390 LYS A NZ  1 
ATOM   2787 N  N   . GLU A 1 391 ? 123.295 133.516 182.052 1.00 145.83 ? 391 GLU A N   1 
ATOM   2788 C  CA  . GLU A 1 391 ? 124.319 132.657 182.634 1.00 145.83 ? 391 GLU A CA  1 
ATOM   2789 C  C   . GLU A 1 391 ? 125.676 133.321 182.455 1.00 145.83 ? 391 GLU A C   1 
ATOM   2790 O  O   . GLU A 1 391 ? 126.011 133.767 181.352 1.00 145.83 ? 391 GLU A O   1 
ATOM   2791 C  CB  . GLU A 1 391 ? 124.315 131.269 181.986 1.00 145.83 ? 391 GLU A CB  1 
ATOM   2792 C  CG  . GLU A 1 391 ? 122.927 130.703 181.709 1.00 145.83 ? 391 GLU A CG  1 
ATOM   2793 C  CD  . GLU A 1 391 ? 122.014 130.743 182.920 1.00 145.83 ? 391 GLU A CD  1 
ATOM   2794 O  OE1 . GLU A 1 391 ? 122.435 130.299 184.008 1.00 145.83 ? 391 GLU A OE1 1 
ATOM   2795 O  OE2 . GLU A 1 391 ? 120.870 131.224 182.780 1.00 145.83 ? 391 GLU A OE2 1 
ATOM   2796 N  N   . LEU A 1 392 ? 126.454 133.384 183.533 1.00 146.67 ? 392 LEU A N   1 
ATOM   2797 C  CA  . LEU A 1 392 ? 127.722 134.104 183.527 1.00 146.67 ? 392 LEU A CA  1 
ATOM   2798 C  C   . LEU A 1 392 ? 128.926 133.234 183.850 1.00 146.67 ? 392 LEU A C   1 
ATOM   2799 O  O   . LEU A 1 392 ? 130.004 133.455 183.293 1.00 146.67 ? 392 LEU A O   1 
ATOM   2800 C  CB  . LEU A 1 392 ? 127.673 135.276 184.523 1.00 146.67 ? 392 LEU A CB  1 
ATOM   2801 C  CG  . LEU A 1 392 ? 126.699 136.432 184.264 1.00 146.67 ? 392 LEU A CG  1 
ATOM   2802 C  CD1 . LEU A 1 392 ? 126.687 137.420 185.425 1.00 146.67 ? 392 LEU A CD1 1 
ATOM   2803 C  CD2 . LEU A 1 392 ? 127.007 137.135 182.947 1.00 146.67 ? 392 LEU A CD2 1 
ATOM   2804 N  N   . GLY A 1 393 ? 128.778 132.252 184.732 1.00 129.23 ? 393 GLY A N   1 
ATOM   2805 C  CA  . GLY A 1 393 ? 129.907 131.496 185.231 1.00 129.23 ? 393 GLY A CA  1 
ATOM   2806 C  C   . GLY A 1 393 ? 130.293 130.324 184.352 1.00 129.23 ? 393 GLY A C   1 
ATOM   2807 O  O   . GLY A 1 393 ? 129.986 130.268 183.158 1.00 129.23 ? 393 GLY A O   1 
ATOM   2808 N  N   . ASP A 1 394 ? 130.998 129.378 184.969 1.00 115.41 ? 394 ASP A N   1 
ATOM   2809 C  CA  . ASP A 1 394 ? 131.441 128.179 184.273 1.00 115.41 ? 394 ASP A CA  1 
ATOM   2810 C  C   . ASP A 1 394 ? 130.232 127.343 183.855 1.00 115.41 ? 394 ASP A C   1 
ATOM   2811 O  O   . ASP A 1 394 ? 129.240 127.282 184.589 1.00 115.41 ? 394 ASP A O   1 
ATOM   2812 C  CB  . ASP A 1 394 ? 132.372 127.367 185.181 1.00 115.41 ? 394 ASP A CB  1 
ATOM   2813 C  CG  . ASP A 1 394 ? 132.994 126.172 184.480 1.00 115.41 ? 394 ASP A CG  1 
ATOM   2814 O  OD1 . ASP A 1 394 ? 132.301 125.147 184.307 1.00 115.41 ? 394 ASP A OD1 1 
ATOM   2815 O  OD2 . ASP A 1 394 ? 134.181 126.257 184.102 1.00 115.41 ? 394 ASP A OD2 1 
ATOM   2816 N  N   . PRO A 1 395 ? 130.273 126.715 182.674 1.00 105.51 ? 395 PRO A N   1 
ATOM   2817 C  CA  . PRO A 1 395 ? 129.119 125.914 182.225 1.00 105.51 ? 395 PRO A CA  1 
ATOM   2818 C  C   . PRO A 1 395 ? 128.755 124.768 183.154 1.00 105.51 ? 395 PRO A C   1 
ATOM   2819 O  O   . PRO A 1 395 ? 127.568 124.440 183.269 1.00 105.51 ? 395 PRO A O   1 
ATOM   2820 C  CB  . PRO A 1 395 ? 129.564 125.401 180.846 1.00 105.51 ? 395 PRO A CB  1 
ATOM   2821 C  CG  . PRO A 1 395 ? 131.051 125.612 180.802 1.00 105.51 ? 395 PRO A CG  1 
ATOM   2822 C  CD  . PRO A 1 395 ? 131.291 126.836 181.619 1.00 105.51 ? 395 PRO A CD  1 
ATOM   2823 N  N   . THR A 1 396 ? 129.734 124.146 183.817 1.00 103.95 ? 396 THR A N   1 
ATOM   2824 C  CA  . THR A 1 396 ? 129.419 123.084 184.768 1.00 103.95 ? 396 THR A CA  1 
ATOM   2825 C  C   . THR A 1 396 ? 128.641 123.623 185.964 1.00 103.95 ? 396 THR A C   1 
ATOM   2826 O  O   . THR A 1 396 ? 127.652 123.017 186.395 1.00 103.95 ? 396 THR A O   1 
ATOM   2827 C  CB  . THR A 1 396 ? 130.702 122.397 185.234 1.00 103.95 ? 396 THR A CB  1 
ATOM   2828 O  OG1 . THR A 1 396 ? 131.527 123.344 185.924 1.00 103.95 ? 396 THR A OG1 1 
ATOM   2829 C  CG2 . THR A 1 396 ? 131.470 121.848 184.042 1.00 103.95 ? 396 THR A CG2 1 
ATOM   2830 N  N   . GLU A 1 397 ? 129.063 124.769 186.501 1.00 113.36 ? 397 GLU A N   1 
ATOM   2831 C  CA  . GLU A 1 397 ? 128.366 125.360 187.638 1.00 113.36 ? 397 GLU A CA  1 
ATOM   2832 C  C   . GLU A 1 397 ? 126.997 125.897 187.233 1.00 113.36 ? 397 GLU A C   1 
ATOM   2833 O  O   . GLU A 1 397 ? 126.031 125.793 187.999 1.00 113.36 ? 397 GLU A O   1 
ATOM   2834 C  CB  . GLU A 1 397 ? 129.231 126.460 188.253 1.00 113.36 ? 397 GLU A CB  1 
ATOM   2835 C  CG  . GLU A 1 397 ? 130.237 125.955 189.281 1.00 113.36 ? 397 GLU A CG  1 
ATOM   2836 C  CD  . GLU A 1 397 ? 131.543 125.478 188.662 1.00 113.36 ? 397 GLU A CD  1 
ATOM   2837 O  OE1 . GLU A 1 397 ? 131.562 125.152 187.457 1.00 113.36 ? 397 GLU A OE1 1 
ATOM   2838 O  OE2 . GLU A 1 397 ? 132.557 125.421 189.389 1.00 113.36 ? 397 GLU A OE2 1 
ATOM   2839 N  N   . VAL A 1 398 ? 126.897 126.471 186.032 1.00 115.44 ? 398 VAL A N   1 
ATOM   2840 C  CA  . VAL A 1 398 ? 125.603 126.908 185.514 1.00 115.44 ? 398 VAL A CA  1 
ATOM   2841 C  C   . VAL A 1 398 ? 124.659 125.719 185.382 1.00 115.44 ? 398 VAL A C   1 
ATOM   2842 O  O   . VAL A 1 398 ? 123.483 125.792 185.760 1.00 115.44 ? 398 VAL A O   1 
ATOM   2843 C  CB  . VAL A 1 398 ? 125.792 127.642 184.172 1.00 115.44 ? 398 VAL A CB  1 
ATOM   2844 C  CG1 . VAL A 1 398 ? 124.466 127.799 183.448 1.00 115.44 ? 398 VAL A CG1 1 
ATOM   2845 C  CG2 . VAL A 1 398 ? 126.433 129.001 184.404 1.00 115.44 ? 398 VAL A CG2 1 
ATOM   2846 N  N   . ALA A 1 399 ? 125.171 124.599 184.871 1.00 101.55 ? 399 ALA A N   1 
ATOM   2847 C  CA  . ALA A 1 399 ? 124.372 123.385 184.761 1.00 101.55 ? 399 ALA A CA  1 
ATOM   2848 C  C   . ALA A 1 399 ? 123.935 122.872 186.124 1.00 101.55 ? 399 ALA A C   1 
ATOM   2849 O  O   . ALA A 1 399 ? 122.792 122.434 186.292 1.00 101.55 ? 399 ALA A O   1 
ATOM   2850 C  CB  . ALA A 1 399 ? 125.168 122.312 184.035 1.00 101.55 ? 399 ALA A CB  1 
ATOM   2851 N  N   . LEU A 1 400 ? 124.840 122.893 187.104 1.00 99.68  ? 400 LEU A N   1 
ATOM   2852 C  CA  . LEU A 1 400 ? 124.502 122.376 188.426 1.00 99.68  ? 400 LEU A CA  1 
ATOM   2853 C  C   . LEU A 1 400 ? 123.443 123.237 189.107 1.00 99.68  ? 400 LEU A C   1 
ATOM   2854 O  O   . LEU A 1 400 ? 122.504 122.708 189.715 1.00 99.68  ? 400 LEU A O   1 
ATOM   2855 C  CB  . LEU A 1 400 ? 125.762 122.278 189.285 1.00 99.68  ? 400 LEU A CB  1 
ATOM   2856 C  CG  . LEU A 1 400 ? 125.826 121.126 190.291 1.00 99.68  ? 400 LEU A CG  1 
ATOM   2857 C  CD1 . LEU A 1 400 ? 125.038 119.910 189.813 1.00 99.68  ? 400 LEU A CD1 1 
ATOM   2858 C  CD2 . LEU A 1 400 ? 127.268 120.746 190.586 1.00 99.68  ? 400 LEU A CD2 1 
ATOM   2859 N  N   . ILE A 1 401 ? 123.562 124.565 189.004 1.00 104.73 ? 401 ILE A N   1 
ATOM   2860 C  CA  . ILE A 1 401 ? 122.547 125.421 189.615 1.00 104.73 ? 401 ILE A CA  1 
ATOM   2861 C  C   . ILE A 1 401 ? 121.227 125.334 188.852 1.00 104.73 ? 401 ILE A C   1 
ATOM   2862 O  O   . ILE A 1 401 ? 120.150 125.413 189.459 1.00 104.73 ? 401 ILE A O   1 
ATOM   2863 C  CB  . ILE A 1 401 ? 123.052 126.873 189.760 1.00 104.73 ? 401 ILE A CB  1 
ATOM   2864 C  CG1 . ILE A 1 401 ? 122.137 127.661 190.701 1.00 104.73 ? 401 ILE A CG1 1 
ATOM   2865 C  CG2 . ILE A 1 401 ? 123.183 127.578 188.417 1.00 104.73 ? 401 ILE A CG2 1 
ATOM   2866 C  CD1 . ILE A 1 401 ? 122.221 127.220 192.143 1.00 104.73 ? 401 ILE A CD1 1 
ATOM   2867 N  N   . ALA A 1 402 ? 121.271 125.136 187.529 1.00 102.61 ? 402 ALA A N   1 
ATOM   2868 C  CA  . ALA A 1 402 ? 120.037 124.932 186.779 1.00 102.61 ? 402 ALA A CA  1 
ATOM   2869 C  C   . ALA A 1 402 ? 119.375 123.612 187.149 1.00 102.61 ? 402 ALA A C   1 
ATOM   2870 O  O   . ALA A 1 402 ? 118.144 123.521 187.165 1.00 102.61 ? 402 ALA A O   1 
ATOM   2871 C  CB  . ALA A 1 402 ? 120.315 124.987 185.278 1.00 102.61 ? 402 ALA A CB  1 
ATOM   2872 N  N   . PHE A 1 403 ? 120.173 122.585 187.440 1.00 102.22 ? 403 PHE A N   1 
ATOM   2873 C  CA  . PHE A 1 403 ? 119.632 121.327 187.941 1.00 102.22 ? 403 PHE A CA  1 
ATOM   2874 C  C   . PHE A 1 403 ? 118.996 121.500 189.312 1.00 102.22 ? 403 PHE A C   1 
ATOM   2875 O  O   . PHE A 1 403 ? 117.925 120.944 189.580 1.00 102.22 ? 403 PHE A O   1 
ATOM   2876 C  CB  . PHE A 1 403 ? 120.739 120.279 188.000 1.00 102.22 ? 403 PHE A CB  1 
ATOM   2877 C  CG  . PHE A 1 403 ? 120.434 119.120 188.905 1.00 102.22 ? 403 PHE A CG  1 
ATOM   2878 C  CD1 . PHE A 1 403 ? 119.488 118.173 188.549 1.00 102.22 ? 403 PHE A CD1 1 
ATOM   2879 C  CD2 . PHE A 1 403 ? 121.110 118.966 190.105 1.00 102.22 ? 403 PHE A CD2 1 
ATOM   2880 C  CE1 . PHE A 1 403 ? 119.214 117.102 189.379 1.00 102.22 ? 403 PHE A CE1 1 
ATOM   2881 C  CE2 . PHE A 1 403 ? 120.840 117.898 190.939 1.00 102.22 ? 403 PHE A CE2 1 
ATOM   2882 C  CZ  . PHE A 1 403 ? 119.890 116.965 190.575 1.00 102.22 ? 403 PHE A CZ  1 
ATOM   2883 N  N   . SER A 1 404 ? 119.657 122.250 190.198 1.00 103.57 ? 404 SER A N   1 
ATOM   2884 C  CA  . SER A 1 404 ? 119.106 122.477 191.531 1.00 103.57 ? 404 SER A CA  1 
ATOM   2885 C  C   . SER A 1 404 ? 117.793 123.247 191.461 1.00 103.57 ? 404 SER A C   1 
ATOM   2886 O  O   . SER A 1 404 ? 116.838 122.928 192.178 1.00 103.57 ? 404 SER A O   1 
ATOM   2887 C  CB  . SER A 1 404 ? 120.118 123.222 192.401 1.00 103.57 ? 404 SER A CB  1 
ATOM   2888 O  OG  . SER A 1 404 ? 120.308 124.546 191.935 1.00 103.57 ? 404 SER A OG  1 
ATOM   2889 N  N   . ASN A 1 405 ? 117.724 124.260 190.597 1.00 106.65 ? 405 ASN A N   1 
ATOM   2890 C  CA  . ASN A 1 405 ? 116.507 125.050 190.464 1.00 106.65 ? 405 ASN A CA  1 
ATOM   2891 C  C   . ASN A 1 405 ? 115.450 124.366 189.607 1.00 106.65 ? 405 ASN A C   1 
ATOM   2892 O  O   . ASN A 1 405 ? 114.287 124.783 189.630 1.00 106.65 ? 405 ASN A O   1 
ATOM   2893 C  CB  . ASN A 1 405 ? 116.839 126.422 189.880 1.00 106.65 ? 405 ASN A CB  1 
ATOM   2894 C  CG  . ASN A 1 405 ? 117.345 127.387 190.928 1.00 106.65 ? 405 ASN A CG  1 
ATOM   2895 O  OD1 . ASN A 1 405 ? 116.881 127.380 192.066 1.00 106.65 ? 405 ASN A OD1 1 
ATOM   2896 N  ND2 . ASN A 1 405 ? 118.307 128.221 190.553 1.00 106.65 ? 405 ASN A ND2 1 
ATOM   2897 N  N   . LYS A 1 406 ? 115.828 123.343 188.841 1.00 102.88 ? 406 LYS A N   1 
ATOM   2898 C  CA  . LYS A 1 406 ? 114.859 122.604 188.040 1.00 102.88 ? 406 LYS A CA  1 
ATOM   2899 C  C   . LYS A 1 406 ? 114.058 121.630 188.894 1.00 102.88 ? 406 LYS A C   1 
ATOM   2900 O  O   . LYS A 1 406 ? 112.847 121.476 188.697 1.00 102.88 ? 406 LYS A O   1 
ATOM   2901 C  CB  . LYS A 1 406 ? 115.582 121.870 186.907 1.00 102.88 ? 406 LYS A CB  1 
ATOM   2902 C  CG  . LYS A 1 406 ? 114.771 120.784 186.219 1.00 102.88 ? 406 LYS A CG  1 
ATOM   2903 C  CD  . LYS A 1 406 ? 115.676 119.852 185.428 1.00 102.88 ? 406 LYS A CD  1 
ATOM   2904 C  CE  . LYS A 1 406 ? 114.944 118.587 185.013 1.00 102.88 ? 406 LYS A CE  1 
ATOM   2905 N  NZ  . LYS A 1 406 ? 115.856 117.619 184.342 1.00 102.88 ? 406 LYS A NZ  1 
ATOM   2906 N  N   . ASN A 1 407 ? 114.709 120.986 189.858 1.00 111.86 ? 407 ASN A N   1 
ATOM   2907 C  CA  . ASN A 1 407 ? 114.068 119.971 190.681 1.00 111.86 ? 407 ASN A CA  1 
ATOM   2908 C  C   . ASN A 1 407 ? 113.553 120.596 191.971 1.00 111.86 ? 407 ASN A C   1 
ATOM   2909 O  O   . ASN A 1 407 ? 114.311 121.248 192.697 1.00 111.86 ? 407 ASN A O   1 
ATOM   2910 C  CB  . ASN A 1 407 ? 115.049 118.839 190.989 1.00 111.86 ? 407 ASN A CB  1 
ATOM   2911 C  CG  . ASN A 1 407 ? 115.630 118.219 189.734 1.00 111.86 ? 407 ASN A CG  1 
ATOM   2912 O  OD1 . ASN A 1 407 ? 115.706 118.864 188.690 1.00 111.86 ? 407 ASN A OD1 1 
ATOM   2913 N  ND2 . ASN A 1 407 ? 116.042 116.962 189.829 1.00 111.86 ? 407 ASN A ND2 1 
ATOM   2914 N  N   . ASN A 1 408 ? 112.261 120.384 192.246 1.00 123.79 ? 408 ASN A N   1 
ATOM   2915 C  CA  . ASN A 1 408 ? 111.577 120.915 193.430 1.00 123.79 ? 408 ASN A CA  1 
ATOM   2916 C  C   . ASN A 1 408 ? 111.701 122.437 193.515 1.00 123.79 ? 408 ASN A C   1 
ATOM   2917 O  O   . ASN A 1 408 ? 111.940 123.002 194.585 1.00 123.79 ? 408 ASN A O   1 
ATOM   2918 C  CB  . ASN A 1 408 ? 112.080 120.243 194.711 1.00 123.79 ? 408 ASN A CB  1 
ATOM   2919 C  CG  . ASN A 1 408 ? 111.093 120.356 195.857 1.00 123.79 ? 408 ASN A CG  1 
ATOM   2920 O  OD1 . ASN A 1 408 ? 111.235 121.207 196.735 1.00 123.79 ? 408 ASN A OD1 1 
ATOM   2921 N  ND2 . ASN A 1 408 ? 110.084 119.492 195.855 1.00 123.79 ? 408 ASN A ND2 1 
ATOM   2922 N  N   . GLN A 1 409 ? 111.554 123.094 192.365 1.00 116.20 ? 409 GLN A N   1 
ATOM   2923 C  CA  . GLN A 1 409 ? 111.454 124.557 192.224 1.00 116.20 ? 409 GLN A CA  1 
ATOM   2924 C  C   . GLN A 1 409 ? 112.748 125.199 192.724 1.00 116.20 ? 409 GLN A C   1 
ATOM   2925 O  O   . GLN A 1 409 ? 113.836 124.681 192.424 1.00 116.20 ? 409 GLN A O   1 
ATOM   2926 C  CB  . GLN A 1 409 ? 110.174 125.033 192.904 1.00 116.20 ? 409 GLN A CB  1 
ATOM   2927 C  CG  . GLN A 1 409 ? 109.559 126.275 192.275 1.00 116.20 ? 409 GLN A CG  1 
ATOM   2928 C  CD  . GLN A 1 409 ? 108.681 125.950 191.083 1.00 116.20 ? 409 GLN A CD  1 
ATOM   2929 O  OE1 . GLN A 1 409 ? 109.172 125.587 190.013 1.00 116.20 ? 409 GLN A OE1 1 
ATOM   2930 N  NE2 . GLN A 1 409 ? 107.371 126.079 191.261 1.00 116.20 ? 409 GLN A NE2 1 
ATOM   2931 N  N   . ASP A 1 410 ? 112.686 126.288 193.488 1.00 117.00 ? 410 ASP A N   1 
ATOM   2932 C  CA  . ASP A 1 410 ? 113.853 127.121 193.754 1.00 117.00 ? 410 ASP A CA  1 
ATOM   2933 C  C   . ASP A 1 410 ? 114.787 126.459 194.760 1.00 117.00 ? 410 ASP A C   1 
ATOM   2934 O  O   . ASP A 1 410 ? 114.350 125.987 195.815 1.00 117.00 ? 410 ASP A O   1 
ATOM   2935 C  CB  . ASP A 1 410 ? 113.404 128.490 194.270 1.00 117.00 ? 410 ASP A CB  1 
ATOM   2936 C  CG  . ASP A 1 410 ? 114.537 129.498 194.328 1.00 117.00 ? 410 ASP A CG  1 
ATOM   2937 O  OD1 . ASP A 1 410 ? 115.576 129.275 193.676 1.00 117.00 ? 410 ASP A OD1 1 
ATOM   2938 O  OD2 . ASP A 1 410 ? 114.388 130.517 195.035 1.00 117.00 ? 410 ASP A OD2 1 
ATOM   2939 N  N   . TYR A 1 411 ? 116.079 126.430 194.428 1.00 114.77 ? 411 TYR A N   1 
ATOM   2940 C  CA  . TYR A 1 411 ? 117.114 125.975 195.346 1.00 114.77 ? 411 TYR A CA  1 
ATOM   2941 C  C   . TYR A 1 411 ? 118.306 126.914 195.446 1.00 114.77 ? 411 TYR A C   1 
ATOM   2942 O  O   . TYR A 1 411 ? 119.150 126.708 196.326 1.00 114.77 ? 411 TYR A O   1 
ATOM   2943 C  CB  . TYR A 1 411 ? 117.616 124.576 194.956 1.00 114.77 ? 411 TYR A CB  1 
ATOM   2944 C  CG  . TYR A 1 411 ? 116.840 123.450 195.598 1.00 114.77 ? 411 TYR A CG  1 
ATOM   2945 C  CD1 . TYR A 1 411 ? 115.570 123.109 195.154 1.00 114.77 ? 411 TYR A CD1 1 
ATOM   2946 C  CD2 . TYR A 1 411 ? 117.377 122.732 196.658 1.00 114.77 ? 411 TYR A CD2 1 
ATOM   2947 C  CE1 . TYR A 1 411 ? 114.861 122.082 195.746 1.00 114.77 ? 411 TYR A CE1 1 
ATOM   2948 C  CE2 . TYR A 1 411 ? 116.676 121.701 197.255 1.00 114.77 ? 411 TYR A CE2 1 
ATOM   2949 C  CZ  . TYR A 1 411 ? 115.418 121.380 196.795 1.00 114.77 ? 411 TYR A CZ  1 
ATOM   2950 O  OH  . TYR A 1 411 ? 114.714 120.355 197.386 1.00 114.77 ? 411 TYR A OH  1 
ATOM   2951 N  N   . ASN A 1 412 ? 118.412 127.927 194.582 1.00 115.04 ? 412 ASN A N   1 
ATOM   2952 C  CA  . ASN A 1 412 ? 119.522 128.868 194.682 1.00 115.04 ? 412 ASN A CA  1 
ATOM   2953 C  C   . ASN A 1 412 ? 119.414 129.792 195.889 1.00 115.04 ? 412 ASN A C   1 
ATOM   2954 O  O   . ASN A 1 412 ? 120.429 130.364 196.301 1.00 115.04 ? 412 ASN A O   1 
ATOM   2955 C  CB  . ASN A 1 412 ? 119.673 129.653 193.362 1.00 115.04 ? 412 ASN A CB  1 
ATOM   2956 C  CG  . ASN A 1 412 ? 118.885 130.981 193.314 1.00 115.04 ? 412 ASN A CG  1 
ATOM   2957 O  OD1 . ASN A 1 412 ? 117.891 131.194 194.014 1.00 115.04 ? 412 ASN A OD1 1 
ATOM   2958 N  ND2 . ASN A 1 412 ? 119.371 131.896 192.485 1.00 115.04 ? 412 ASN A ND2 1 
ATOM   2959 N  N   . GLU A 1 413 ? 118.215 129.957 196.459 1.00 117.51 ? 413 GLU A N   1 
ATOM   2960 C  CA  . GLU A 1 413 ? 118.059 130.857 197.597 1.00 117.51 ? 413 GLU A CA  1 
ATOM   2961 C  C   . GLU A 1 413 ? 118.745 130.324 198.847 1.00 117.51 ? 413 GLU A C   1 
ATOM   2962 O  O   . GLU A 1 413 ? 118.960 131.088 199.794 1.00 117.51 ? 413 GLU A O   1 
ATOM   2963 C  CB  . GLU A 1 413 ? 116.579 131.112 197.898 1.00 117.51 ? 413 GLU A CB  1 
ATOM   2964 C  CG  . GLU A 1 413 ? 115.889 130.027 198.719 1.00 117.51 ? 413 GLU A CG  1 
ATOM   2965 C  CD  . GLU A 1 413 ? 115.177 129.001 197.867 1.00 117.51 ? 413 GLU A CD  1 
ATOM   2966 O  OE1 . GLU A 1 413 ? 115.800 128.478 196.923 1.00 117.51 ? 413 GLU A OE1 1 
ATOM   2967 O  OE2 . GLU A 1 413 ? 113.990 128.722 198.139 1.00 117.51 ? 413 GLU A OE2 1 
ATOM   2968 N  N   . ILE A 1 414 ? 119.093 129.036 198.870 1.00 118.54 ? 414 ILE A N   1 
ATOM   2969 C  CA  . ILE A 1 414 ? 119.777 128.469 200.024 1.00 118.54 ? 414 ILE A CA  1 
ATOM   2970 C  C   . ILE A 1 414 ? 121.236 128.907 200.098 1.00 118.54 ? 414 ILE A C   1 
ATOM   2971 O  O   . ILE A 1 414 ? 121.851 128.795 201.164 1.00 118.54 ? 414 ILE A O   1 
ATOM   2972 C  CB  . ILE A 1 414 ? 119.656 126.932 200.005 1.00 118.54 ? 414 ILE A CB  1 
ATOM   2973 C  CG1 . ILE A 1 414 ? 119.474 126.384 201.422 1.00 118.54 ? 414 ILE A CG1 1 
ATOM   2974 C  CG2 . ILE A 1 414 ? 120.851 126.281 199.322 1.00 118.54 ? 414 ILE A CG2 1 
ATOM   2975 C  CD1 . ILE A 1 414 ? 118.136 126.718 202.035 1.00 118.54 ? 414 ILE A CD1 1 
ATOM   2976 N  N   . ARG A 1 415 ? 121.805 129.424 199.003 1.00 120.57 ? 415 ARG A N   1 
ATOM   2977 C  CA  . ARG A 1 415 ? 123.220 129.787 199.011 1.00 120.57 ? 415 ARG A CA  1 
ATOM   2978 C  C   . ARG A 1 415 ? 123.469 131.069 199.799 1.00 120.57 ? 415 ARG A C   1 
ATOM   2979 O  O   . ARG A 1 415 ? 124.464 131.169 200.526 1.00 120.57 ? 415 ARG A O   1 
ATOM   2980 C  CB  . ARG A 1 415 ? 123.745 129.933 197.582 1.00 120.57 ? 415 ARG A CB  1 
ATOM   2981 C  CG  . ARG A 1 415 ? 125.242 130.212 197.518 1.00 120.57 ? 415 ARG A CG  1 
ATOM   2982 C  CD  . ARG A 1 415 ? 125.856 129.830 196.183 1.00 120.57 ? 415 ARG A CD  1 
ATOM   2983 N  NE  . ARG A 1 415 ? 125.049 130.264 195.050 1.00 120.57 ? 415 ARG A NE  1 
ATOM   2984 C  CZ  . ARG A 1 415 ? 124.611 129.458 194.093 1.00 120.57 ? 415 ARG A CZ  1 
ATOM   2985 N  NH1 . ARG A 1 415 ? 124.877 128.163 194.105 1.00 120.57 ? 415 ARG A NH1 1 
ATOM   2986 N  NH2 . ARG A 1 415 ? 123.891 129.965 193.098 1.00 120.57 ? 415 ARG A NH2 1 
ATOM   2987 N  N   . GLU A 1 416 ? 122.586 132.063 199.664 1.00 124.35 ? 416 GLU A N   1 
ATOM   2988 C  CA  . GLU A 1 416 ? 122.778 133.324 200.376 1.00 124.35 ? 416 GLU A CA  1 
ATOM   2989 C  C   . GLU A 1 416 ? 122.658 133.165 201.886 1.00 124.35 ? 416 GLU A C   1 
ATOM   2990 O  O   . GLU A 1 416 ? 123.222 133.980 202.624 1.00 124.35 ? 416 GLU A O   1 
ATOM   2991 C  CB  . GLU A 1 416 ? 121.802 134.414 199.895 1.00 124.35 ? 416 GLU A CB  1 
ATOM   2992 C  CG  . GLU A 1 416 ? 121.746 134.748 198.381 1.00 124.35 ? 416 GLU A CG  1 
ATOM   2993 C  CD  . GLU A 1 416 ? 121.319 133.608 197.476 1.00 124.35 ? 416 GLU A CD  1 
ATOM   2994 O  OE1 . GLU A 1 416 ? 120.715 132.643 197.981 1.00 124.35 ? 416 GLU A OE1 1 
ATOM   2995 O  OE2 . GLU A 1 416 ? 121.587 133.681 196.258 1.00 124.35 ? 416 GLU A OE2 1 
ATOM   2996 N  N   . LYS A 1 417 ? 121.945 132.150 202.364 1.00 124.78 ? 417 LYS A N   1 
ATOM   2997 C  CA  . LYS A 1 417 ? 122.002 131.801 203.783 1.00 124.78 ? 417 LYS A CA  1 
ATOM   2998 C  C   . LYS A 1 417 ? 123.064 130.734 204.036 1.00 124.78 ? 417 LYS A C   1 
ATOM   2999 O  O   . LYS A 1 417 ? 122.832 129.733 204.713 1.00 124.78 ? 417 LYS A O   1 
ATOM   3000 C  CB  . LYS A 1 417 ? 120.632 131.343 204.267 1.00 124.78 ? 417 LYS A CB  1 
ATOM   3001 C  CG  . LYS A 1 417 ? 119.884 130.460 203.284 1.00 124.78 ? 417 LYS A CG  1 
ATOM   3002 C  CD  . LYS A 1 417 ? 118.652 129.849 203.929 1.00 124.78 ? 417 LYS A CD  1 
ATOM   3003 C  CE  . LYS A 1 417 ? 119.034 128.884 205.040 1.00 124.78 ? 417 LYS A CE  1 
ATOM   3004 N  NZ  . LYS A 1 417 ? 120.011 127.859 204.582 1.00 124.78 ? 417 LYS A NZ  1 
ATOM   3005 N  N   . PHE A 1 418 ? 124.256 130.972 203.490 1.00 131.33 ? 418 PHE A N   1 
ATOM   3006 C  CA  . PHE A 1 418 ? 125.393 130.067 203.646 1.00 131.33 ? 418 PHE A CA  1 
ATOM   3007 C  C   . PHE A 1 418 ? 126.644 130.863 203.297 1.00 131.33 ? 418 PHE A C   1 
ATOM   3008 O  O   . PHE A 1 418 ? 126.826 131.242 202.136 1.00 131.33 ? 418 PHE A O   1 
ATOM   3009 C  CB  . PHE A 1 418 ? 125.250 128.841 202.748 1.00 131.33 ? 418 PHE A CB  1 
ATOM   3010 C  CG  . PHE A 1 418 ? 124.737 127.617 203.459 1.00 131.33 ? 418 PHE A CG  1 
ATOM   3011 C  CD1 . PHE A 1 418 ? 125.480 127.017 204.459 1.00 131.33 ? 418 PHE A CD1 1 
ATOM   3012 C  CD2 . PHE A 1 418 ? 123.517 127.060 203.115 1.00 131.33 ? 418 PHE A CD2 1 
ATOM   3013 C  CE1 . PHE A 1 418 ? 125.013 125.890 205.109 1.00 131.33 ? 418 PHE A CE1 1 
ATOM   3014 C  CE2 . PHE A 1 418 ? 123.043 125.934 203.761 1.00 131.33 ? 418 PHE A CE2 1 
ATOM   3015 C  CZ  . PHE A 1 418 ? 123.792 125.348 204.759 1.00 131.33 ? 418 PHE A CZ  1 
ATOM   3016 N  N   . ILE A 1 419 ? 127.498 131.118 204.291 1.00 137.54 ? 419 ILE A N   1 
ATOM   3017 C  CA  . ILE A 1 419 ? 128.685 131.931 204.043 1.00 137.54 ? 419 ILE A CA  1 
ATOM   3018 C  C   . ILE A 1 419 ? 129.701 131.131 203.227 1.00 137.54 ? 419 ILE A C   1 
ATOM   3019 O  O   . ILE A 1 419 ? 129.688 129.895 203.192 1.00 137.54 ? 419 ILE A O   1 
ATOM   3020 C  CB  . ILE A 1 419 ? 129.282 132.430 205.372 1.00 137.54 ? 419 ILE A CB  1 
ATOM   3021 C  CG1 . ILE A 1 419 ? 130.199 133.640 205.155 1.00 137.54 ? 419 ILE A CG1 1 
ATOM   3022 C  CG2 . ILE A 1 419 ? 130.038 131.319 206.080 1.00 137.54 ? 419 ILE A CG2 1 
ATOM   3023 C  CD1 . ILE A 1 419 ? 129.540 134.783 204.413 1.00 137.54 ? 419 ILE A CD1 1 
ATOM   3024 N  N   . ARG A 1 420 ? 130.573 131.853 202.529 1.00 138.94 ? 420 ARG A N   1 
ATOM   3025 C  CA  . ARG A 1 420 ? 131.596 131.265 201.665 1.00 138.94 ? 420 ARG A CA  1 
ATOM   3026 C  C   . ARG A 1 420 ? 132.955 131.644 202.248 1.00 138.94 ? 420 ARG A C   1 
ATOM   3027 O  O   . ARG A 1 420 ? 133.541 132.663 201.875 1.00 138.94 ? 420 ARG A O   1 
ATOM   3028 C  CB  . ARG A 1 420 ? 131.443 131.745 200.215 1.00 138.94 ? 420 ARG A CB  1 
ATOM   3029 C  CG  . ARG A 1 420 ? 130.056 131.526 199.615 1.00 138.94 ? 420 ARG A CG  1 
ATOM   3030 C  CD  . ARG A 1 420 ? 129.194 132.779 199.725 1.00 138.94 ? 420 ARG A CD  1 
ATOM   3031 N  NE  . ARG A 1 420 ? 128.020 132.728 198.862 1.00 138.94 ? 420 ARG A NE  1 
ATOM   3032 C  CZ  . ARG A 1 420 ? 126.984 133.549 198.963 1.00 138.94 ? 420 ARG A CZ  1 
ATOM   3033 N  NH1 . ARG A 1 420 ? 126.937 134.492 199.890 1.00 138.94 ? 420 ARG A NH1 1 
ATOM   3034 N  NH2 . ARG A 1 420 ? 125.969 133.422 198.114 1.00 138.94 ? 420 ARG A NH2 1 
ATOM   3035 N  N   . GLU A 1 421 ? 133.456 130.816 203.167 1.00 149.34 ? 421 GLU A N   1 
ATOM   3036 C  CA  . GLU A 1 421 ? 134.673 131.159 203.896 1.00 149.34 ? 421 GLU A CA  1 
ATOM   3037 C  C   . GLU A 1 421 ? 135.927 130.814 203.099 1.00 149.34 ? 421 GLU A C   1 
ATOM   3038 O  O   . GLU A 1 421 ? 136.716 131.699 202.749 1.00 149.34 ? 421 GLU A O   1 
ATOM   3039 C  CB  . GLU A 1 421 ? 134.683 130.449 205.253 1.00 149.34 ? 421 GLU A CB  1 
ATOM   3040 C  CG  . GLU A 1 421 ? 135.713 130.988 206.233 1.00 149.34 ? 421 GLU A CG  1 
ATOM   3041 C  CD  . GLU A 1 421 ? 137.020 130.223 206.186 1.00 149.34 ? 421 GLU A CD  1 
ATOM   3042 O  OE1 . GLU A 1 421 ? 137.003 129.037 205.796 1.00 149.34 ? 421 GLU A OE1 1 
ATOM   3043 O  OE2 . GLU A 1 421 ? 138.065 130.808 206.537 1.00 149.34 ? 421 GLU A OE2 1 
ATOM   3044 N  N   . GLY A 1 422 ? 136.128 129.532 202.803 1.00 150.10 ? 422 GLY A N   1 
ATOM   3045 C  CA  . GLY A 1 422 ? 137.340 129.101 202.132 1.00 150.10 ? 422 GLY A CA  1 
ATOM   3046 C  C   . GLY A 1 422 ? 137.111 128.572 200.732 1.00 150.10 ? 422 GLY A C   1 
ATOM   3047 O  O   . GLY A 1 422 ? 136.558 127.483 200.558 1.00 150.10 ? 422 GLY A O   1 
ATOM   3048 N  N   . GLU A 1 423 ? 137.547 129.325 199.725 1.00 142.24 ? 423 GLU A N   1 
ATOM   3049 C  CA  . GLU A 1 423 ? 137.334 128.973 198.324 1.00 142.24 ? 423 GLU A CA  1 
ATOM   3050 C  C   . GLU A 1 423 ? 138.688 128.805 197.646 1.00 142.24 ? 423 GLU A C   1 
ATOM   3051 O  O   . GLU A 1 423 ? 139.431 129.779 197.483 1.00 142.24 ? 423 GLU A O   1 
ATOM   3052 C  CB  . GLU A 1 423 ? 136.493 130.034 197.614 1.00 142.24 ? 423 GLU A CB  1 
ATOM   3053 C  CG  . GLU A 1 423 ? 134.991 129.864 197.796 1.00 142.24 ? 423 GLU A CG  1 
ATOM   3054 C  CD  . GLU A 1 423 ? 134.537 130.136 199.217 1.00 142.24 ? 423 GLU A CD  1 
ATOM   3055 O  OE1 . GLU A 1 423 ? 135.046 131.096 199.832 1.00 142.24 ? 423 GLU A OE1 1 
ATOM   3056 O  OE2 . GLU A 1 423 ? 133.676 129.386 199.721 1.00 142.24 ? 423 GLU A OE2 1 
ATOM   3057 N  N   . ILE A 1 424 ? 139.004 127.575 197.260 1.00 139.59 ? 424 ILE A N   1 
ATOM   3058 C  CA  . ILE A 1 424 ? 140.234 127.309 196.505 1.00 139.59 ? 424 ILE A CA  1 
ATOM   3059 C  C   . ILE A 1 424 ? 140.086 127.878 195.099 1.00 139.59 ? 424 ILE A C   1 
ATOM   3060 O  O   . ILE A 1 424 ? 139.024 127.701 194.474 1.00 139.59 ? 424 ILE A O   1 
ATOM   3061 C  CB  . ILE A 1 424 ? 140.519 125.802 196.478 1.00 139.59 ? 424 ILE A CB  1 
ATOM   3062 C  CG1 . ILE A 1 424 ? 141.236 125.379 197.763 1.00 139.59 ? 424 ILE A CG1 1 
ATOM   3063 C  CG2 . ILE A 1 424 ? 141.337 125.396 195.253 1.00 139.59 ? 424 ILE A CG2 1 
ATOM   3064 C  CD1 . ILE A 1 424 ? 141.602 123.912 197.808 1.00 139.59 ? 424 ILE A CD1 1 
ATOM   3065 N  N   . PRO A 1 425 ? 141.104 128.566 194.555 1.00 146.40 ? 425 PRO A N   1 
ATOM   3066 C  CA  . PRO A 1 425 ? 140.936 129.250 193.262 1.00 146.40 ? 425 PRO A CA  1 
ATOM   3067 C  C   . PRO A 1 425 ? 140.887 128.333 192.046 1.00 146.40 ? 425 PRO A C   1 
ATOM   3068 O  O   . PRO A 1 425 ? 140.951 128.826 190.914 1.00 146.40 ? 425 PRO A O   1 
ATOM   3069 C  CB  . PRO A 1 425 ? 142.159 130.174 193.201 1.00 146.40 ? 425 PRO A CB  1 
ATOM   3070 C  CG  . PRO A 1 425 ? 143.178 129.499 194.054 1.00 146.40 ? 425 PRO A CG  1 
ATOM   3071 C  CD  . PRO A 1 425 ? 142.406 128.868 195.175 1.00 146.40 ? 425 PRO A CD  1 
ATOM   3072 N  N   . PHE A 1 426 ? 140.783 127.018 192.262 1.00 143.41 ? 426 PHE A N   1 
ATOM   3073 C  CA  . PHE A 1 426 ? 140.624 126.021 191.198 1.00 143.41 ? 426 PHE A CA  1 
ATOM   3074 C  C   . PHE A 1 426 ? 141.801 126.062 190.219 1.00 143.41 ? 426 PHE A C   1 
ATOM   3075 O  O   . PHE A 1 426 ? 141.660 126.387 189.037 1.00 143.41 ? 426 PHE A O   1 
ATOM   3076 C  CB  . PHE A 1 426 ? 139.282 126.204 190.475 1.00 143.41 ? 426 PHE A CB  1 
ATOM   3077 C  CG  . PHE A 1 426 ? 138.940 125.088 189.529 1.00 143.41 ? 426 PHE A CG  1 
ATOM   3078 C  CD1 . PHE A 1 426 ? 139.071 123.765 189.917 1.00 143.41 ? 426 PHE A CD1 1 
ATOM   3079 C  CD2 . PHE A 1 426 ? 138.485 125.365 188.250 1.00 143.41 ? 426 PHE A CD2 1 
ATOM   3080 C  CE1 . PHE A 1 426 ? 138.754 122.739 189.046 1.00 143.41 ? 426 PHE A CE1 1 
ATOM   3081 C  CE2 . PHE A 1 426 ? 138.167 124.343 187.375 1.00 143.41 ? 426 PHE A CE2 1 
ATOM   3082 C  CZ  . PHE A 1 426 ? 138.302 123.029 187.774 1.00 143.41 ? 426 PHE A CZ  1 
ATOM   3083 N  N   . ASP A 1 427 ? 142.979 125.740 190.747 1.00 144.96 ? 427 ASP A N   1 
ATOM   3084 C  CA  . ASP A 1 427 ? 144.191 125.689 189.943 1.00 144.96 ? 427 ASP A CA  1 
ATOM   3085 C  C   . ASP A 1 427 ? 144.099 124.559 188.920 1.00 144.96 ? 427 ASP A C   1 
ATOM   3086 O  O   . ASP A 1 427 ? 143.428 123.547 189.138 1.00 144.96 ? 427 ASP A O   1 
ATOM   3087 C  CB  . ASP A 1 427 ? 145.411 125.509 190.856 1.00 144.96 ? 427 ASP A CB  1 
ATOM   3088 C  CG  . ASP A 1 427 ? 146.685 125.194 190.094 1.00 144.96 ? 427 ASP A CG  1 
ATOM   3089 O  OD1 . ASP A 1 427 ? 146.925 125.822 189.041 1.00 144.96 ? 427 ASP A OD1 1 
ATOM   3090 O  OD2 . ASP A 1 427 ? 147.448 124.315 190.548 1.00 144.96 ? 427 ASP A OD2 1 
ATOM   3091 N  N   . SER A 1 428 ? 144.778 124.750 187.782 1.00 148.40 ? 428 SER A N   1 
ATOM   3092 C  CA  . SER A 1 428 ? 144.746 123.772 186.697 1.00 148.40 ? 428 SER A CA  1 
ATOM   3093 C  C   . SER A 1 428 ? 145.351 122.429 187.092 1.00 148.40 ? 428 SER A C   1 
ATOM   3094 O  O   . SER A 1 428 ? 145.102 121.428 186.412 1.00 148.40 ? 428 SER A O   1 
ATOM   3095 C  CB  . SER A 1 428 ? 145.474 124.327 185.472 1.00 148.40 ? 428 SER A CB  1 
ATOM   3096 O  OG  . SER A 1 428 ? 145.180 123.564 184.315 1.00 148.40 ? 428 SER A OG  1 
ATOM   3097 N  N   . ASP A 1 429 ? 146.136 122.381 188.167 1.00 142.28 ? 429 ASP A N   1 
ATOM   3098 C  CA  . ASP A 1 429 ? 146.684 121.138 188.689 1.00 142.28 ? 429 ASP A CA  1 
ATOM   3099 C  C   . ASP A 1 429 ? 146.012 120.705 189.988 1.00 142.28 ? 429 ASP A C   1 
ATOM   3100 O  O   . ASP A 1 429 ? 146.559 119.863 190.707 1.00 142.28 ? 429 ASP A O   1 
ATOM   3101 C  CB  . ASP A 1 429 ? 148.194 121.282 188.898 1.00 142.28 ? 429 ASP A CB  1 
ATOM   3102 C  CG  . ASP A 1 429 ? 148.927 119.956 188.824 1.00 142.28 ? 429 ASP A CG  1 
ATOM   3103 O  OD1 . ASP A 1 429 ? 148.280 118.934 188.511 1.00 142.28 ? 429 ASP A OD1 1 
ATOM   3104 O  OD2 . ASP A 1 429 ? 150.149 119.935 189.082 1.00 142.28 ? 429 ASP A OD2 1 
ATOM   3105 N  N   . ARG A 1 430 ? 144.841 121.256 190.307 1.00 137.84 ? 430 ARG A N   1 
ATOM   3106 C  CA  . ARG A 1 430 ? 144.240 121.061 191.621 1.00 137.84 ? 430 ARG A CA  1 
ATOM   3107 C  C   . ARG A 1 430 ? 142.927 120.292 191.576 1.00 137.84 ? 430 ARG A C   1 
ATOM   3108 O  O   . ARG A 1 430 ? 142.809 119.256 192.243 1.00 137.84 ? 430 ARG A O   1 
ATOM   3109 C  CB  . ARG A 1 430 ? 144.037 122.428 192.296 1.00 137.84 ? 430 ARG A CB  1 
ATOM   3110 C  CG  . ARG A 1 430 ? 143.175 122.408 193.542 1.00 137.84 ? 430 ARG A CG  1 
ATOM   3111 C  CD  . ARG A 1 430 ? 143.959 121.913 194.754 1.00 137.84 ? 430 ARG A CD  1 
ATOM   3112 N  NE  . ARG A 1 430 ? 143.942 120.459 194.875 1.00 137.84 ? 430 ARG A NE  1 
ATOM   3113 C  CZ  . ARG A 1 430 ? 144.319 119.793 195.958 1.00 137.84 ? 430 ARG A CZ  1 
ATOM   3114 N  NH1 . ARG A 1 430 ? 144.755 120.419 197.039 1.00 137.84 ? 430 ARG A NH1 1 
ATOM   3115 N  NH2 . ARG A 1 430 ? 144.257 118.464 195.956 1.00 137.84 ? 430 ARG A NH2 1 
ATOM   3116 N  N   . LYS A 1 431 ? 141.938 120.770 190.806 1.00 134.49 ? 431 LYS A N   1 
ATOM   3117 C  CA  . LYS A 1 431 ? 140.608 120.148 190.705 1.00 134.49 ? 431 LYS A CA  1 
ATOM   3118 C  C   . LYS A 1 431 ? 139.928 120.009 192.066 1.00 134.49 ? 431 LYS A C   1 
ATOM   3119 O  O   . LYS A 1 431 ? 139.251 119.019 192.341 1.00 134.49 ? 431 LYS A O   1 
ATOM   3120 C  CB  . LYS A 1 431 ? 140.671 118.790 189.994 1.00 134.49 ? 431 LYS A CB  1 
ATOM   3121 C  CG  . LYS A 1 431 ? 141.390 118.808 188.660 1.00 134.49 ? 431 LYS A CG  1 
ATOM   3122 C  CD  . LYS A 1 431 ? 140.823 119.902 187.769 1.00 134.49 ? 431 LYS A CD  1 
ATOM   3123 C  CE  . LYS A 1 431 ? 141.912 120.658 187.052 1.00 134.49 ? 431 LYS A CE  1 
ATOM   3124 N  NZ  . LYS A 1 431 ? 142.464 121.690 187.961 1.00 134.49 ? 431 LYS A NZ  1 
ATOM   3125 N  N   . LEU A 1 432 ? 140.095 121.012 192.922 1.00 134.72 ? 432 LEU A N   1 
ATOM   3126 C  CA  . LEU A 1 432 ? 139.533 120.980 194.269 1.00 134.72 ? 432 LEU A CA  1 
ATOM   3127 C  C   . LEU A 1 432 ? 138.879 122.319 194.600 1.00 134.72 ? 432 LEU A C   1 
ATOM   3128 O  O   . LEU A 1 432 ? 139.175 122.943 195.620 1.00 134.72 ? 432 LEU A O   1 
ATOM   3129 C  CB  . LEU A 1 432 ? 140.599 120.609 195.298 1.00 134.72 ? 432 LEU A CB  1 
ATOM   3130 C  CG  . LEU A 1 432 ? 140.134 120.060 196.648 1.00 134.72 ? 432 LEU A CG  1 
ATOM   3131 C  CD1 . LEU A 1 432 ? 139.676 118.617 196.513 1.00 134.72 ? 432 LEU A CD1 1 
ATOM   3132 C  CD2 . LEU A 1 432 ? 141.241 120.189 197.680 1.00 134.72 ? 432 LEU A CD2 1 
ATOM   3133 N  N   . MET A 1 433 ? 138.010 122.796 193.705 1.00 131.19 ? 433 MET A N   1 
ATOM   3134 C  CA  . MET A 1 433 ? 137.242 124.014 193.947 1.00 131.19 ? 433 MET A CA  1 
ATOM   3135 C  C   . MET A 1 433 ? 136.440 123.880 195.236 1.00 131.19 ? 433 MET A C   1 
ATOM   3136 O  O   . MET A 1 433 ? 135.495 123.088 195.311 1.00 131.19 ? 433 MET A O   1 
ATOM   3137 C  CB  . MET A 1 433 ? 136.317 124.311 192.765 1.00 131.19 ? 433 MET A CB  1 
ATOM   3138 C  CG  . MET A 1 433 ? 135.328 125.440 193.010 1.00 131.19 ? 433 MET A CG  1 
ATOM   3139 S  SD  . MET A 1 433 ? 135.988 127.059 192.571 1.00 131.19 ? 433 MET A SD  1 
ATOM   3140 C  CE  . MET A 1 433 ? 134.573 128.104 192.912 1.00 131.19 ? 433 MET A CE  1 
ATOM   3141 N  N   . SER A 1 434 ? 136.813 124.652 196.252 1.00 137.35 ? 434 SER A N   1 
ATOM   3142 C  CA  . SER A 1 434 ? 136.380 124.423 197.621 1.00 137.35 ? 434 SER A CA  1 
ATOM   3143 C  C   . SER A 1 434 ? 135.374 125.476 198.068 1.00 137.35 ? 434 SER A C   1 
ATOM   3144 O  O   . SER A 1 434 ? 135.176 126.509 197.423 1.00 137.35 ? 434 SER A O   1 
ATOM   3145 C  CB  . SER A 1 434 ? 137.585 124.409 198.569 1.00 137.35 ? 434 SER A CB  1 
ATOM   3146 O  OG  . SER A 1 434 ? 138.062 125.721 198.806 1.00 137.35 ? 434 SER A OG  1 
ATOM   3147 N  N   . THR A 1 435 ? 134.738 125.189 199.203 1.00 136.46 ? 435 THR A N   1 
ATOM   3148 C  CA  . THR A 1 435 ? 133.739 126.060 199.805 1.00 136.46 ? 435 THR A CA  1 
ATOM   3149 C  C   . THR A 1 435 ? 133.653 125.713 201.286 1.00 136.46 ? 435 THR A C   1 
ATOM   3150 O  O   . THR A 1 435 ? 133.698 124.537 201.650 1.00 136.46 ? 435 THR A O   1 
ATOM   3151 C  CB  . THR A 1 435 ? 132.374 125.897 199.117 1.00 136.46 ? 435 THR A CB  1 
ATOM   3152 O  OG1 . THR A 1 435 ? 132.444 126.420 197.785 1.00 136.46 ? 435 THR A OG1 1 
ATOM   3153 C  CG2 . THR A 1 435 ? 131.279 126.634 199.874 1.00 136.46 ? 435 THR A CG2 1 
ATOM   3154 N  N   . LEU A 1 436 ? 133.573 126.734 202.137 1.00 141.42 ? 436 LEU A N   1 
ATOM   3155 C  CA  . LEU A 1 436 ? 133.418 126.533 203.570 1.00 141.42 ? 436 LEU A CA  1 
ATOM   3156 C  C   . LEU A 1 436 ? 132.317 127.442 204.095 1.00 141.42 ? 436 LEU A C   1 
ATOM   3157 O  O   . LEU A 1 436 ? 132.254 128.622 203.738 1.00 141.42 ? 436 LEU A O   1 
ATOM   3158 C  CB  . LEU A 1 436 ? 134.730 126.804 204.317 1.00 141.42 ? 436 LEU A CB  1 
ATOM   3159 C  CG  . LEU A 1 436 ? 135.688 125.617 204.454 1.00 141.42 ? 436 LEU A CG  1 
ATOM   3160 C  CD1 . LEU A 1 436 ? 136.581 125.488 203.229 1.00 141.42 ? 436 LEU A CD1 1 
ATOM   3161 C  CD2 . LEU A 1 436 ? 136.525 125.748 205.712 1.00 141.42 ? 436 LEU A CD2 1 
ATOM   3162 N  N   . HIS A 1 437 ? 131.453 126.889 204.945 1.00 144.63 ? 437 HIS A N   1 
ATOM   3163 C  CA  . HIS A 1 437 ? 130.353 127.642 205.528 1.00 144.63 ? 437 HIS A CA  1 
ATOM   3164 C  C   . HIS A 1 437 ? 130.310 127.427 207.034 1.00 144.63 ? 437 HIS A C   1 
ATOM   3165 O  O   . HIS A 1 437 ? 130.802 126.424 207.557 1.00 144.63 ? 437 HIS A O   1 
ATOM   3166 C  CB  . HIS A 1 437 ? 129.000 127.267 204.893 1.00 144.63 ? 437 HIS A CB  1 
ATOM   3167 C  CG  . HIS A 1 437 ? 128.611 125.831 205.068 1.00 144.63 ? 437 HIS A CG  1 
ATOM   3168 N  ND1 . HIS A 1 437 ? 128.587 124.936 204.020 1.00 144.63 ? 437 HIS A ND1 1 
ATOM   3169 C  CD2 . HIS A 1 437 ? 128.195 125.142 206.158 1.00 144.63 ? 437 HIS A CD2 1 
ATOM   3170 C  CE1 . HIS A 1 437 ? 128.190 123.755 204.459 1.00 144.63 ? 437 HIS A CE1 1 
ATOM   3171 N  NE2 . HIS A 1 437 ? 127.947 123.853 205.754 1.00 144.63 ? 437 HIS A NE2 1 
ATOM   3172 N  N   . THR A 1 438 ? 129.714 128.400 207.729 1.00 150.28 ? 438 THR A N   1 
ATOM   3173 C  CA  . THR A 1 438 ? 129.583 128.374 209.182 1.00 150.28 ? 438 THR A CA  1 
ATOM   3174 C  C   . THR A 1 438 ? 128.125 128.436 209.628 1.00 150.28 ? 438 THR A C   1 
ATOM   3175 O  O   . THR A 1 438 ? 127.850 128.757 210.788 1.00 150.28 ? 438 THR A O   1 
ATOM   3176 C  CB  . THR A 1 438 ? 130.369 129.525 209.817 1.00 150.28 ? 438 THR A CB  1 
ATOM   3177 O  OG1 . THR A 1 438 ? 129.809 130.777 209.399 1.00 150.28 ? 438 THR A OG1 1 
ATOM   3178 C  CG2 . THR A 1 438 ? 131.835 129.471 209.411 1.00 150.28 ? 438 THR A CG2 1 
ATOM   3179 N  N   . PHE A 1 439 ? 127.183 128.137 208.731 1.00 147.14 ? 439 PHE A N   1 
ATOM   3180 C  CA  . PHE A 1 439 ? 125.767 128.266 209.063 1.00 147.14 ? 439 PHE A CA  1 
ATOM   3181 C  C   . PHE A 1 439 ? 125.301 127.130 209.969 1.00 147.14 ? 439 PHE A C   1 
ATOM   3182 O  O   . PHE A 1 439 ? 124.872 127.362 211.105 1.00 147.14 ? 439 PHE A O   1 
ATOM   3183 C  CB  . PHE A 1 439 ? 124.932 128.313 207.781 1.00 147.14 ? 439 PHE A CB  1 
ATOM   3184 C  CG  . PHE A 1 439 ? 123.532 128.816 207.986 1.00 147.14 ? 439 PHE A CG  1 
ATOM   3185 C  CD1 . PHE A 1 439 ? 123.276 130.176 208.066 1.00 147.14 ? 439 PHE A CD1 1 
ATOM   3186 C  CD2 . PHE A 1 439 ? 122.471 127.932 208.096 1.00 147.14 ? 439 PHE A CD2 1 
ATOM   3187 C  CE1 . PHE A 1 439 ? 121.988 130.644 208.254 1.00 147.14 ? 439 PHE A CE1 1 
ATOM   3188 C  CE2 . PHE A 1 439 ? 121.181 128.393 208.284 1.00 147.14 ? 439 PHE A CE2 1 
ATOM   3189 C  CZ  . PHE A 1 439 ? 120.940 129.751 208.363 1.00 147.14 ? 439 PHE A CZ  1 
ATOM   3190 N  N   . ASN A 1 440 ? 125.377 125.892 209.483 1.00 147.04 ? 440 ASN A N   1 
ATOM   3191 C  CA  . ASN A 1 440 ? 125.034 124.717 210.273 1.00 147.04 ? 440 ASN A CA  1 
ATOM   3192 C  C   . ASN A 1 440 ? 126.264 123.950 210.730 1.00 147.04 ? 440 ASN A C   1 
ATOM   3193 O  O   . ASN A 1 440 ? 126.431 123.700 211.928 1.00 147.04 ? 440 ASN A O   1 
ATOM   3194 C  CB  . ASN A 1 440 ? 124.104 123.790 209.474 1.00 147.04 ? 440 ASN A CB  1 
ATOM   3195 C  CG  . ASN A 1 440 ? 124.512 123.664 208.020 1.00 147.04 ? 440 ASN A CG  1 
ATOM   3196 O  OD1 . ASN A 1 440 ? 125.619 124.044 207.638 1.00 147.04 ? 440 ASN A OD1 1 
ATOM   3197 N  ND2 . ASN A 1 440 ? 123.619 123.124 207.199 1.00 147.04 ? 440 ASN A ND2 1 
ATOM   3198 N  N   . GLU A 1 441 ? 127.133 123.567 209.801 1.00 151.16 ? 441 GLU A N   1 
ATOM   3199 C  CA  . GLU A 1 441 ? 128.423 122.989 210.138 1.00 151.16 ? 441 GLU A CA  1 
ATOM   3200 C  C   . GLU A 1 441 ? 129.442 124.104 210.331 1.00 151.16 ? 441 GLU A C   1 
ATOM   3201 O  O   . GLU A 1 441 ? 129.370 125.153 209.686 1.00 151.16 ? 441 GLU A O   1 
ATOM   3202 C  CB  . GLU A 1 441 ? 128.891 122.025 209.046 1.00 151.16 ? 441 GLU A CB  1 
ATOM   3203 C  CG  . GLU A 1 441 ? 128.296 120.626 209.144 1.00 151.16 ? 441 GLU A CG  1 
ATOM   3204 C  CD  . GLU A 1 441 ? 126.833 120.579 208.749 1.00 151.16 ? 441 GLU A CD  1 
ATOM   3205 O  OE1 . GLU A 1 441 ? 126.477 121.168 207.708 1.00 151.16 ? 441 GLU A OE1 1 
ATOM   3206 O  OE2 . GLU A 1 441 ? 126.038 119.951 209.481 1.00 151.16 ? 441 GLU A OE2 1 
ATOM   3207 N  N   . ASN A 1 442 ? 130.395 123.871 211.235 1.00 159.26 ? 442 ASN A N   1 
ATOM   3208 C  CA  . ASN A 1 442 ? 131.331 124.927 211.610 1.00 159.26 ? 442 ASN A CA  1 
ATOM   3209 C  C   . ASN A 1 442 ? 132.368 125.165 210.517 1.00 159.26 ? 442 ASN A C   1 
ATOM   3210 O  O   . ASN A 1 442 ? 132.512 126.285 210.013 1.00 159.26 ? 442 ASN A O   1 
ATOM   3211 C  CB  . ASN A 1 442 ? 132.009 124.577 212.935 1.00 159.26 ? 442 ASN A CB  1 
ATOM   3212 C  CG  . ASN A 1 442 ? 131.214 125.046 214.137 1.00 159.26 ? 442 ASN A CG  1 
ATOM   3213 O  OD1 . ASN A 1 442 ? 130.029 125.360 214.027 1.00 159.26 ? 442 ASN A OD1 1 
ATOM   3214 N  ND2 . ASN A 1 442 ? 131.865 125.098 215.293 1.00 159.26 ? 442 ASN A ND2 1 
ATOM   3215 N  N   . LYS A 1 443 ? 133.100 124.122 210.137 1.00 154.58 ? 443 LYS A N   1 
ATOM   3216 C  CA  . LYS A 1 443 ? 134.207 124.225 209.190 1.00 154.58 ? 443 LYS A CA  1 
ATOM   3217 C  C   . LYS A 1 443 ? 134.020 123.234 208.048 1.00 154.58 ? 443 LYS A C   1 
ATOM   3218 O  O   . LYS A 1 443 ? 134.929 122.483 207.690 1.00 154.58 ? 443 LYS A O   1 
ATOM   3219 C  CB  . LYS A 1 443 ? 135.540 123.997 209.899 1.00 154.58 ? 443 LYS A CB  1 
ATOM   3220 C  CG  . LYS A 1 443 ? 136.744 124.609 209.200 1.00 154.58 ? 443 LYS A CG  1 
ATOM   3221 C  CD  . LYS A 1 443 ? 138.023 123.871 209.561 1.00 154.58 ? 443 LYS A CD  1 
ATOM   3222 C  CE  . LYS A 1 443 ? 138.076 122.502 208.899 1.00 154.58 ? 443 LYS A CE  1 
ATOM   3223 N  NZ  . LYS A 1 443 ? 138.111 122.596 207.413 1.00 154.58 ? 443 LYS A NZ  1 
ATOM   3224 N  N   . ALA A 1 444 ? 132.821 123.225 207.461 1.00 145.89 ? 444 ALA A N   1 
ATOM   3225 C  CA  . ALA A 1 444 ? 132.450 122.237 206.452 1.00 145.89 ? 444 ALA A CA  1 
ATOM   3226 C  C   . ALA A 1 444 ? 133.346 122.306 205.222 1.00 145.89 ? 444 ALA A C   1 
ATOM   3227 O  O   . ALA A 1 444 ? 133.291 123.269 204.451 1.00 145.89 ? 444 ALA A O   1 
ATOM   3228 C  CB  . ALA A 1 444 ? 130.989 122.419 206.041 1.00 145.89 ? 444 ALA A CB  1 
ATOM   3229 N  N   . MET A 1 445 ? 134.168 121.276 205.034 1.00 139.97 ? 445 MET A N   1 
ATOM   3230 C  CA  . MET A 1 445 ? 135.147 121.234 203.952 1.00 139.97 ? 445 MET A CA  1 
ATOM   3231 C  C   . MET A 1 445 ? 134.399 120.723 202.724 1.00 139.97 ? 445 MET A C   1 
ATOM   3232 O  O   . MET A 1 445 ? 134.256 119.518 202.508 1.00 139.97 ? 445 MET A O   1 
ATOM   3233 C  CB  . MET A 1 445 ? 136.320 120.337 204.333 1.00 139.97 ? 445 MET A CB  1 
ATOM   3234 C  CG  . MET A 1 445 ? 137.346 120.034 203.243 1.00 139.97 ? 445 MET A CG  1 
ATOM   3235 S  SD  . MET A 1 445 ? 138.065 121.520 202.505 1.00 139.97 ? 445 MET A SD  1 
ATOM   3236 C  CE  . MET A 1 445 ? 137.197 121.645 200.950 1.00 139.97 ? 445 MET A CE  1 
ATOM   3237 N  N   . LEU A 1 446 ? 133.894 121.653 201.920 1.00 135.25 ? 446 LEU A N   1 
ATOM   3238 C  CA  . LEU A 1 446 ? 132.985 121.344 200.822 1.00 135.25 ? 446 LEU A CA  1 
ATOM   3239 C  C   . LEU A 1 446 ? 133.714 121.605 199.510 1.00 135.25 ? 446 LEU A C   1 
ATOM   3240 O  O   . LEU A 1 446 ? 134.068 122.752 199.217 1.00 135.25 ? 446 LEU A O   1 
ATOM   3241 C  CB  . LEU A 1 446 ? 131.726 122.208 200.915 1.00 135.25 ? 446 LEU A CB  1 
ATOM   3242 C  CG  . LEU A 1 446 ? 130.772 122.038 202.102 1.00 135.25 ? 446 LEU A CG  1 
ATOM   3243 C  CD1 . LEU A 1 446 ? 129.666 123.086 202.082 1.00 135.25 ? 446 LEU A CD1 1 
ATOM   3244 C  CD2 . LEU A 1 446 ? 130.212 120.637 202.184 1.00 135.25 ? 446 LEU A CD2 1 
ATOM   3245 N  N   . THR A 1 447 ? 133.932 120.555 198.719 1.00 123.71 ? 447 THR A N   1 
ATOM   3246 C  CA  . THR A 1 447 ? 134.685 120.711 197.481 1.00 123.71 ? 447 THR A CA  1 
ATOM   3247 C  C   . THR A 1 447 ? 134.132 119.802 196.393 1.00 123.71 ? 447 THR A C   1 
ATOM   3248 O  O   . THR A 1 447 ? 133.551 118.750 196.670 1.00 123.71 ? 447 THR A O   1 
ATOM   3249 C  CB  . THR A 1 447 ? 136.175 120.409 197.675 1.00 123.71 ? 447 THR A CB  1 
ATOM   3250 O  OG1 . THR A 1 447 ? 136.826 120.378 196.399 1.00 123.71 ? 447 THR A OG1 1 
ATOM   3251 C  CG2 . THR A 1 447 ? 136.364 119.067 198.367 1.00 123.71 ? 447 THR A CG2 1 
ATOM   3252 N  N   . LYS A 1 448 ? 134.337 120.223 195.150 1.00 115.25 ? 448 LYS A N   1 
ATOM   3253 C  CA  . LYS A 1 448 ? 134.022 119.445 193.962 1.00 115.25 ? 448 LYS A CA  1 
ATOM   3254 C  C   . LYS A 1 448 ? 135.298 119.168 193.177 1.00 115.25 ? 448 LYS A C   1 
ATOM   3255 O  O   . LYS A 1 448 ? 136.366 119.716 193.465 1.00 115.25 ? 448 LYS A O   1 
ATOM   3256 C  CB  . LYS A 1 448 ? 133.005 120.178 193.080 1.00 115.25 ? 448 LYS A CB  1 
ATOM   3257 C  CG  . LYS A 1 448 ? 133.590 121.357 192.315 1.00 115.25 ? 448 LYS A CG  1 
ATOM   3258 C  CD  . LYS A 1 448 ? 132.704 121.787 191.152 1.00 115.25 ? 448 LYS A CD  1 
ATOM   3259 C  CE  . LYS A 1 448 ? 131.228 121.770 191.517 1.00 115.25 ? 448 LYS A CE  1 
ATOM   3260 N  NZ  . LYS A 1 448 ? 130.373 122.125 190.352 1.00 115.25 ? 448 LYS A NZ  1 
ATOM   3261 N  N   . GLY A 1 449 ? 135.179 118.308 192.173 1.00 111.72 ? 449 GLY A N   1 
ATOM   3262 C  CA  . GLY A 1 449 ? 136.318 117.987 191.340 1.00 111.72 ? 449 GLY A CA  1 
ATOM   3263 C  C   . GLY A 1 449 ? 136.037 116.768 190.486 1.00 111.72 ? 449 GLY A C   1 
ATOM   3264 O  O   . GLY A 1 449 ? 134.901 116.300 190.390 1.00 111.72 ? 449 GLY A O   1 
ATOM   3265 N  N   . GLY A 1 450 ? 137.104 116.264 189.869 1.00 108.81 ? 450 GLY A N   1 
ATOM   3266 C  CA  . GLY A 1 450 ? 137.016 115.103 189.017 1.00 108.81 ? 450 GLY A CA  1 
ATOM   3267 C  C   . GLY A 1 450 ? 136.720 113.841 189.801 1.00 108.81 ? 450 GLY A C   1 
ATOM   3268 O  O   . GLY A 1 450 ? 136.893 113.787 191.023 1.00 108.81 ? 450 GLY A O   1 
ATOM   3269 N  N   . PRO A 1 451 ? 136.256 112.798 189.108 1.00 111.08 ? 451 PRO A N   1 
ATOM   3270 C  CA  . PRO A 1 451 ? 135.890 111.555 189.801 1.00 111.08 ? 451 PRO A CA  1 
ATOM   3271 C  C   . PRO A 1 451 ? 137.094 110.819 190.366 1.00 111.08 ? 451 PRO A C   1 
ATOM   3272 O  O   . PRO A 1 451 ? 137.130 110.492 191.557 1.00 111.08 ? 451 PRO A O   1 
ATOM   3273 C  CB  . PRO A 1 451 ? 135.197 110.726 188.709 1.00 111.08 ? 451 PRO A CB  1 
ATOM   3274 C  CG  . PRO A 1 451 ? 135.160 111.598 187.475 1.00 111.08 ? 451 PRO A CG  1 
ATOM   3275 C  CD  . PRO A 1 451 ? 136.189 112.655 187.647 1.00 111.08 ? 451 PRO A CD  1 
ATOM   3276 N  N   . ASP A 1 452 ? 138.094 110.573 189.516 1.00 116.85 ? 452 ASP A N   1 
ATOM   3277 C  CA  . ASP A 1 452 ? 139.249 109.784 189.930 1.00 116.85 ? 452 ASP A CA  1 
ATOM   3278 C  C   . ASP A 1 452 ? 140.112 110.527 190.939 1.00 116.85 ? 452 ASP A C   1 
ATOM   3279 O  O   . ASP A 1 452 ? 140.697 109.899 191.829 1.00 116.85 ? 452 ASP A O   1 
ATOM   3280 C  CB  . ASP A 1 452 ? 140.080 109.389 188.710 1.00 116.85 ? 452 ASP A CB  1 
ATOM   3281 C  CG  . ASP A 1 452 ? 140.482 110.582 187.867 1.00 116.85 ? 452 ASP A CG  1 
ATOM   3282 O  OD1 . ASP A 1 452 ? 141.527 111.195 188.167 1.00 116.85 ? 452 ASP A OD1 1 
ATOM   3283 O  OD2 . ASP A 1 452 ? 139.752 110.910 186.909 1.00 116.85 ? 452 ASP A OD2 1 
ATOM   3284 N  N   . VAL A 1 453 ? 140.204 111.852 190.822 1.00 117.77 ? 453 VAL A N   1 
ATOM   3285 C  CA  . VAL A 1 453 ? 141.030 112.626 191.745 1.00 117.77 ? 453 VAL A CA  1 
ATOM   3286 C  C   . VAL A 1 453 ? 140.452 112.575 193.157 1.00 117.77 ? 453 VAL A C   1 
ATOM   3287 O  O   . VAL A 1 453 ? 141.179 112.344 194.130 1.00 117.77 ? 453 VAL A O   1 
ATOM   3288 C  CB  . VAL A 1 453 ? 141.186 114.070 191.240 1.00 117.77 ? 453 VAL A CB  1 
ATOM   3289 C  CG1 . VAL A 1 453 ? 142.384 114.733 191.899 1.00 117.77 ? 453 VAL A CG1 1 
ATOM   3290 C  CG2 . VAL A 1 453 ? 141.322 114.091 189.726 1.00 117.77 ? 453 VAL A CG2 1 
ATOM   3291 N  N   . MET A 1 454 ? 139.137 112.777 193.292 1.00 118.66 ? 454 MET A N   1 
ATOM   3292 C  CA  . MET A 1 454 ? 138.498 112.616 194.597 1.00 118.66 ? 454 MET A CA  1 
ATOM   3293 C  C   . MET A 1 454 ? 138.541 111.170 195.075 1.00 118.66 ? 454 MET A C   1 
ATOM   3294 O  O   . MET A 1 454 ? 138.683 110.917 196.277 1.00 118.66 ? 454 MET A O   1 
ATOM   3295 C  CB  . MET A 1 454 ? 137.052 113.118 194.567 1.00 118.66 ? 454 MET A CB  1 
ATOM   3296 C  CG  . MET A 1 454 ? 136.768 114.593 194.213 1.00 118.66 ? 454 MET A CG  1 
ATOM   3297 S  SD  . MET A 1 454 ? 137.915 115.892 194.747 1.00 118.66 ? 454 MET A SD  1 
ATOM   3298 C  CE  . MET A 1 454 ? 139.112 115.992 193.431 1.00 118.66 ? 454 MET A CE  1 
ATOM   3299 N  N   . PHE A 1 455 ? 138.407 110.208 194.158 1.00 121.33 ? 455 PHE A N   1 
ATOM   3300 C  CA  . PHE A 1 455 ? 138.440 108.804 194.561 1.00 121.33 ? 455 PHE A CA  1 
ATOM   3301 C  C   . PHE A 1 455 ? 139.800 108.425 195.136 1.00 121.33 ? 455 PHE A C   1 
ATOM   3302 O  O   . PHE A 1 455 ? 139.882 107.666 196.108 1.00 121.33 ? 455 PHE A O   1 
ATOM   3303 C  CB  . PHE A 1 455 ? 138.081 107.902 193.378 1.00 121.33 ? 455 PHE A CB  1 
ATOM   3304 C  CG  . PHE A 1 455 ? 136.612 107.893 193.042 1.00 121.33 ? 455 PHE A CG  1 
ATOM   3305 C  CD1 . PHE A 1 455 ? 135.690 108.512 193.870 1.00 121.33 ? 455 PHE A CD1 1 
ATOM   3306 C  CD2 . PHE A 1 455 ? 136.157 107.265 191.893 1.00 121.33 ? 455 PHE A CD2 1 
ATOM   3307 C  CE1 . PHE A 1 455 ? 134.343 108.505 193.562 1.00 121.33 ? 455 PHE A CE1 1 
ATOM   3308 C  CE2 . PHE A 1 455 ? 134.810 107.254 191.579 1.00 121.33 ? 455 PHE A CE2 1 
ATOM   3309 C  CZ  . PHE A 1 455 ? 133.902 107.875 192.415 1.00 121.33 ? 455 PHE A CZ  1 
ATOM   3310 N  N   . ALA A 1 456 ? 140.876 108.947 194.551 1.00 129.80 ? 456 ALA A N   1 
ATOM   3311 C  CA  . ALA A 1 456 ? 142.212 108.734 195.089 1.00 129.80 ? 456 ALA A CA  1 
ATOM   3312 C  C   . ALA A 1 456 ? 142.548 109.674 196.240 1.00 129.80 ? 456 ALA A C   1 
ATOM   3313 O  O   . ALA A 1 456 ? 143.544 109.442 196.933 1.00 129.80 ? 456 ALA A O   1 
ATOM   3314 C  CB  . ALA A 1 456 ? 143.256 108.888 193.981 1.00 129.80 ? 456 ALA A CB  1 
ATOM   3315 N  N   . ARG A 1 457 ? 141.752 110.721 196.459 1.00 128.49 ? 457 ARG A N   1 
ATOM   3316 C  CA  . ARG A 1 457 ? 142.023 111.706 197.500 1.00 128.49 ? 457 ARG A CA  1 
ATOM   3317 C  C   . ARG A 1 457 ? 141.103 111.560 198.707 1.00 128.49 ? 457 ARG A C   1 
ATOM   3318 O  O   . ARG A 1 457 ? 141.585 111.468 199.840 1.00 128.49 ? 457 ARG A O   1 
ATOM   3319 C  CB  . ARG A 1 457 ? 141.907 113.120 196.918 1.00 128.49 ? 457 ARG A CB  1 
ATOM   3320 C  CG  . ARG A 1 457 ? 143.195 113.640 196.291 1.00 128.49 ? 457 ARG A CG  1 
ATOM   3321 C  CD  . ARG A 1 457 ? 143.059 115.095 195.867 1.00 128.49 ? 457 ARG A CD  1 
ATOM   3322 N  NE  . ARG A 1 457 ? 142.182 115.838 196.763 1.00 128.49 ? 457 ARG A NE  1 
ATOM   3323 C  CZ  . ARG A 1 457 ? 142.563 116.350 197.925 1.00 128.49 ? 457 ARG A CZ  1 
ATOM   3324 N  NH1 . ARG A 1 457 ? 143.811 116.242 198.351 1.00 128.49 ? 457 ARG A NH1 1 
ATOM   3325 N  NH2 . ARG A 1 457 ? 141.669 116.980 198.680 1.00 128.49 ? 457 ARG A NH2 1 
ATOM   3326 N  N   . CYS A 1 458 ? 139.789 111.549 198.494 1.00 127.03 ? 458 CYS A N   1 
ATOM   3327 C  CA  . CYS A 1 458 ? 138.858 111.338 199.594 1.00 127.03 ? 458 CYS A CA  1 
ATOM   3328 C  C   . CYS A 1 458 ? 138.962 109.904 200.104 1.00 127.03 ? 458 CYS A C   1 
ATOM   3329 O  O   . CYS A 1 458 ? 139.252 108.971 199.350 1.00 127.03 ? 458 CYS A O   1 
ATOM   3330 C  CB  . CYS A 1 458 ? 137.426 111.653 199.157 1.00 127.03 ? 458 CYS A CB  1 
ATOM   3331 S  SG  . CYS A 1 458 ? 136.464 110.239 198.572 1.00 127.03 ? 458 CYS A SG  1 
ATOM   3332 N  N   . SER A 1 459 ? 138.747 109.735 201.412 1.00 132.84 ? 459 SER A N   1 
ATOM   3333 C  CA  . SER A 1 459 ? 139.007 108.446 202.041 1.00 132.84 ? 459 SER A CA  1 
ATOM   3334 C  C   . SER A 1 459 ? 137.932 108.060 203.052 1.00 132.84 ? 459 SER A C   1 
ATOM   3335 O  O   . SER A 1 459 ? 138.251 107.515 204.114 1.00 132.84 ? 459 SER A O   1 
ATOM   3336 C  CB  . SER A 1 459 ? 140.377 108.441 202.721 1.00 132.84 ? 459 SER A CB  1 
ATOM   3337 O  OG  . SER A 1 459 ? 140.431 109.402 203.761 1.00 132.84 ? 459 SER A OG  1 
ATOM   3338 N  N   . TYR A 1 460 ? 136.662 108.325 202.749 1.00 138.37 ? 460 TYR A N   1 
ATOM   3339 C  CA  . TYR A 1 460 ? 135.572 107.900 203.616 1.00 138.37 ? 460 TYR A CA  1 
ATOM   3340 C  C   . TYR A 1 460 ? 134.326 107.668 202.771 1.00 138.37 ? 460 TYR A C   1 
ATOM   3341 O  O   . TYR A 1 460 ? 134.098 108.360 201.775 1.00 138.37 ? 460 TYR A O   1 
ATOM   3342 C  CB  . TYR A 1 460 ? 135.270 108.930 204.714 1.00 138.37 ? 460 TYR A CB  1 
ATOM   3343 C  CG  . TYR A 1 460 ? 136.273 108.974 205.846 1.00 138.37 ? 460 TYR A CG  1 
ATOM   3344 C  CD1 . TYR A 1 460 ? 136.264 108.016 206.850 1.00 138.37 ? 460 TYR A CD1 1 
ATOM   3345 C  CD2 . TYR A 1 460 ? 137.222 109.985 205.913 1.00 138.37 ? 460 TYR A CD2 1 
ATOM   3346 C  CE1 . TYR A 1 460 ? 137.178 108.059 207.887 1.00 138.37 ? 460 TYR A CE1 1 
ATOM   3347 C  CE2 . TYR A 1 460 ? 138.139 110.037 206.945 1.00 138.37 ? 460 TYR A CE2 1 
ATOM   3348 C  CZ  . TYR A 1 460 ? 138.113 109.073 207.929 1.00 138.37 ? 460 TYR A CZ  1 
ATOM   3349 O  OH  . TYR A 1 460 ? 139.026 109.123 208.957 1.00 138.37 ? 460 TYR A OH  1 
ATOM   3350 N  N   . VAL A 1 461 ? 133.524 106.689 203.179 1.00 143.24 ? 461 VAL A N   1 
ATOM   3351 C  CA  . VAL A 1 461 ? 132.283 106.357 202.495 1.00 143.24 ? 461 VAL A CA  1 
ATOM   3352 C  C   . VAL A 1 461 ? 131.124 106.970 203.271 1.00 143.24 ? 461 VAL A C   1 
ATOM   3353 O  O   . VAL A 1 461 ? 131.124 107.021 204.504 1.00 143.24 ? 461 VAL A O   1 
ATOM   3354 C  CB  . VAL A 1 461 ? 132.109 104.826 202.343 1.00 143.24 ? 461 VAL A CB  1 
ATOM   3355 C  CG1 . VAL A 1 461 ? 130.963 104.498 201.400 1.00 143.24 ? 461 VAL A CG1 1 
ATOM   3356 C  CG2 . VAL A 1 461 ? 133.396 104.185 201.865 1.00 143.24 ? 461 VAL A CG2 1 
ATOM   3357 N  N   . PHE A 1 462 ? 130.115 107.449 202.541 1.00 137.33 ? 462 PHE A N   1 
ATOM   3358 C  CA  . PHE A 1 462 ? 128.943 108.095 203.133 1.00 137.33 ? 462 PHE A CA  1 
ATOM   3359 C  C   . PHE A 1 462 ? 127.743 107.159 203.031 1.00 137.33 ? 462 PHE A C   1 
ATOM   3360 O  O   . PHE A 1 462 ? 127.022 107.165 202.029 1.00 137.33 ? 462 PHE A O   1 
ATOM   3361 C  CB  . PHE A 1 462 ? 128.649 109.428 202.452 1.00 137.33 ? 462 PHE A CB  1 
ATOM   3362 C  CG  . PHE A 1 462 ? 127.579 110.232 203.133 1.00 137.33 ? 462 PHE A CG  1 
ATOM   3363 C  CD1 . PHE A 1 462 ? 127.859 110.938 204.292 1.00 137.33 ? 462 PHE A CD1 1 
ATOM   3364 C  CD2 . PHE A 1 462 ? 126.295 110.285 202.616 1.00 137.33 ? 462 PHE A CD2 1 
ATOM   3365 C  CE1 . PHE A 1 462 ? 126.879 111.680 204.923 1.00 137.33 ? 462 PHE A CE1 1 
ATOM   3366 C  CE2 . PHE A 1 462 ? 125.310 111.025 203.243 1.00 137.33 ? 462 PHE A CE2 1 
ATOM   3367 C  CZ  . PHE A 1 462 ? 125.602 111.723 204.397 1.00 137.33 ? 462 PHE A CZ  1 
ATOM   3368 N  N   . LEU A 1 463 ? 127.528 106.359 204.073 1.00 142.54 ? 463 LEU A N   1 
ATOM   3369 C  CA  . LEU A 1 463 ? 126.318 105.551 204.238 1.00 142.54 ? 463 LEU A CA  1 
ATOM   3370 C  C   . LEU A 1 463 ? 125.624 106.043 205.504 1.00 142.54 ? 463 LEU A C   1 
ATOM   3371 O  O   . LEU A 1 463 ? 125.965 105.615 206.610 1.00 142.54 ? 463 LEU A O   1 
ATOM   3372 C  CB  . LEU A 1 463 ? 126.630 104.048 204.310 1.00 142.54 ? 463 LEU A CB  1 
ATOM   3373 C  CG  . LEU A 1 463 ? 126.642 103.200 203.031 1.00 142.54 ? 463 LEU A CG  1 
ATOM   3374 C  CD1 . LEU A 1 463 ? 125.217 102.890 202.593 1.00 142.54 ? 463 LEU A CD1 1 
ATOM   3375 C  CD2 . LEU A 1 463 ? 127.408 103.855 201.897 1.00 142.54 ? 463 LEU A CD2 1 
ATOM   3376 N  N   . ASP A 1 464 ? 124.650 106.940 205.325 1.00 144.62 ? 464 ASP A N   1 
ATOM   3377 C  CA  . ASP A 1 464 ? 123.907 107.593 206.410 1.00 144.62 ? 464 ASP A CA  1 
ATOM   3378 C  C   . ASP A 1 464 ? 124.913 108.327 207.290 1.00 144.62 ? 464 ASP A C   1 
ATOM   3379 O  O   . ASP A 1 464 ? 125.660 109.171 206.765 1.00 144.62 ? 464 ASP A O   1 
ATOM   3380 C  CB  . ASP A 1 464 ? 123.018 106.567 207.119 1.00 144.62 ? 464 ASP A CB  1 
ATOM   3381 C  CG  . ASP A 1 464 ? 122.137 105.794 206.156 1.00 144.62 ? 464 ASP A CG  1 
ATOM   3382 O  OD1 . ASP A 1 464 ? 122.679 105.034 205.327 1.00 144.62 ? 464 ASP A OD1 1 
ATOM   3383 O  OD2 . ASP A 1 464 ? 120.899 105.948 206.228 1.00 144.62 ? 464 ASP A OD2 1 
ATOM   3384 N  N   . GLY A 1 465 ? 124.976 108.061 208.592 1.00 142.81 ? 465 GLY A N   1 
ATOM   3385 C  CA  . GLY A 1 465 ? 125.940 108.706 209.458 1.00 142.81 ? 465 GLY A CA  1 
ATOM   3386 C  C   . GLY A 1 465 ? 127.304 108.061 209.507 1.00 142.81 ? 465 GLY A C   1 
ATOM   3387 O  O   . GLY A 1 465 ? 128.208 108.593 210.157 1.00 142.81 ? 465 GLY A O   1 
ATOM   3388 N  N   . GLU A 1 466 ? 127.481 106.924 208.840 1.00 143.77 ? 466 GLU A N   1 
ATOM   3389 C  CA  . GLU A 1 466 ? 128.758 106.226 208.847 1.00 143.77 ? 466 GLU A CA  1 
ATOM   3390 C  C   . GLU A 1 466 ? 129.755 106.945 207.947 1.00 143.77 ? 466 GLU A C   1 
ATOM   3391 O  O   . GLU A 1 466 ? 129.443 107.279 206.800 1.00 143.77 ? 466 GLU A O   1 
ATOM   3392 C  CB  . GLU A 1 466 ? 128.572 104.778 208.391 1.00 143.77 ? 466 GLU A CB  1 
ATOM   3393 C  CG  . GLU A 1 466 ? 129.823 104.122 207.827 1.00 143.77 ? 466 GLU A CG  1 
ATOM   3394 C  CD  . GLU A 1 466 ? 129.510 102.904 206.980 1.00 143.77 ? 466 GLU A CD  1 
ATOM   3395 O  OE1 . GLU A 1 466 ? 128.383 102.377 207.089 1.00 143.77 ? 466 GLU A OE1 1 
ATOM   3396 O  OE2 . GLU A 1 466 ? 130.389 102.476 206.203 1.00 143.77 ? 466 GLU A OE2 1 
ATOM   3397 N  N   . GLU A 1 467 ? 130.957 107.191 208.477 1.00 144.55 ? 467 GLU A N   1 
ATOM   3398 C  CA  . GLU A 1 467 ? 132.071 107.773 207.724 1.00 144.55 ? 467 GLU A CA  1 
ATOM   3399 C  C   . GLU A 1 467 ? 133.279 106.870 207.964 1.00 144.55 ? 467 GLU A C   1 
ATOM   3400 O  O   . GLU A 1 467 ? 134.011 107.028 208.943 1.00 144.55 ? 467 GLU A O   1 
ATOM   3401 C  CB  . GLU A 1 467 ? 132.329 109.223 208.140 1.00 144.55 ? 467 GLU A CB  1 
ATOM   3402 C  CG  . GLU A 1 467 ? 131.167 110.161 207.841 1.00 144.55 ? 467 GLU A CG  1 
ATOM   3403 C  CD  . GLU A 1 467 ? 131.098 111.338 208.793 1.00 144.55 ? 467 GLU A CD  1 
ATOM   3404 O  OE1 . GLU A 1 467 ? 131.704 111.263 209.882 1.00 144.55 ? 467 GLU A OE1 1 
ATOM   3405 O  OE2 . GLU A 1 467 ? 130.435 112.340 208.451 1.00 144.55 ? 467 GLU A OE2 1 
ATOM   3406 N  N   . LYS A 1 468 ? 133.350 105.813 207.129 1.00 146.20 ? 468 LYS A N   1 
ATOM   3407 C  CA  . LYS A 1 468 ? 134.409 104.771 207.246 1.00 146.20 ? 468 LYS A CA  1 
ATOM   3408 C  C   . LYS A 1 468 ? 135.190 104.724 205.928 1.00 146.20 ? 468 LYS A C   1 
ATOM   3409 O  O   . LYS A 1 468 ? 134.596 105.055 204.890 1.00 146.20 ? 468 LYS A O   1 
ATOM   3410 C  CB  . LYS A 1 468 ? 133.749 103.433 207.602 1.00 146.20 ? 468 LYS A CB  1 
ATOM   3411 C  CG  . LYS A 1 468 ? 133.102 103.336 208.977 1.00 146.20 ? 468 LYS A CG  1 
ATOM   3412 C  CD  . LYS A 1 468 ? 132.449 102.000 209.255 1.00 146.20 ? 468 LYS A CD  1 
ATOM   3413 C  CE  . LYS A 1 468 ? 131.836 101.925 210.636 1.00 146.20 ? 468 LYS A CE  1 
ATOM   3414 N  NZ  . LYS A 1 468 ? 131.185 100.615 210.870 1.00 146.20 ? 468 LYS A NZ  1 
ATOM   3415 N  N   . PRO A 1 469 ? 136.480 104.324 205.914 1.00 150.24 ? 469 PRO A N   1 
ATOM   3416 C  CA  . PRO A 1 469 ? 137.322 104.452 204.714 1.00 150.24 ? 469 PRO A CA  1 
ATOM   3417 C  C   . PRO A 1 469 ? 136.993 103.461 203.606 1.00 150.24 ? 469 PRO A C   1 
ATOM   3418 O  O   . PRO A 1 469 ? 136.171 102.555 203.758 1.00 150.24 ? 469 PRO A O   1 
ATOM   3419 C  CB  . PRO A 1 469 ? 138.739 104.211 205.250 1.00 150.24 ? 469 PRO A CB  1 
ATOM   3420 C  CG  . PRO A 1 469 ? 138.661 104.531 206.698 1.00 150.24 ? 469 PRO A CG  1 
ATOM   3421 C  CD  . PRO A 1 469 ? 137.288 104.116 207.129 1.00 150.24 ? 469 PRO A CD  1 
ATOM   3422 N  N   . MET A 1 470 ? 137.664 103.657 202.472 1.00 147.51 ? 470 MET A N   1 
ATOM   3423 C  CA  . MET A 1 470 ? 137.429 102.848 201.284 1.00 147.51 ? 470 MET A CA  1 
ATOM   3424 C  C   . MET A 1 470 ? 138.017 101.449 201.439 1.00 147.51 ? 470 MET A C   1 
ATOM   3425 O  O   . MET A 1 470 ? 139.045 101.258 202.093 1.00 147.51 ? 470 MET A O   1 
ATOM   3426 C  CB  . MET A 1 470 ? 138.049 103.525 200.059 1.00 147.51 ? 470 MET A CB  1 
ATOM   3427 C  CG  . MET A 1 470 ? 137.150 103.609 198.832 1.00 147.51 ? 470 MET A CG  1 
ATOM   3428 S  SD  . MET A 1 470 ? 135.607 104.522 199.057 1.00 147.51 ? 470 MET A SD  1 
ATOM   3429 C  CE  . MET A 1 470 ? 136.136 105.945 200.014 1.00 147.51 ? 470 MET A CE  1 
ATOM   3430 N  N   . THR A 1 471 ? 137.353 100.468 200.830 1.00 150.32 ? 471 THR A N   1 
ATOM   3431 C  CA  . THR A 1 471 ? 137.897 99.132  200.646 1.00 150.32 ? 471 THR A CA  1 
ATOM   3432 C  C   . THR A 1 471 ? 137.894 98.784  199.158 1.00 150.32 ? 471 THR A C   1 
ATOM   3433 O  O   . THR A 1 471 ? 137.484 99.585  198.313 1.00 150.32 ? 471 THR A O   1 
ATOM   3434 C  CB  . THR A 1 471 ? 137.120 98.102  201.470 1.00 150.32 ? 471 THR A CB  1 
ATOM   3435 O  OG1 . THR A 1 471 ? 135.731 98.146  201.119 1.00 150.32 ? 471 THR A OG1 1 
ATOM   3436 C  CG2 . THR A 1 471 ? 137.292 98.363  202.956 1.00 150.32 ? 471 THR A CG2 1 
ATOM   3437 N  N   . GLU A 1 472 ? 138.360 97.575  198.829 1.00 157.19 ? 472 GLU A N   1 
ATOM   3438 C  CA  . GLU A 1 472 ? 138.507 97.193  197.427 1.00 157.19 ? 472 GLU A CA  1 
ATOM   3439 C  C   . GLU A 1 472 ? 137.156 97.045  196.734 1.00 157.19 ? 472 GLU A C   1 
ATOM   3440 O  O   . GLU A 1 472 ? 136.990 97.498  195.597 1.00 157.19 ? 472 GLU A O   1 
ATOM   3441 C  CB  . GLU A 1 472 ? 139.322 95.902  197.310 1.00 157.19 ? 472 GLU A CB  1 
ATOM   3442 C  CG  . GLU A 1 472 ? 138.927 94.801  198.281 1.00 157.19 ? 472 GLU A CG  1 
ATOM   3443 C  CD  . GLU A 1 472 ? 138.097 93.717  197.621 1.00 157.19 ? 472 GLU A CD  1 
ATOM   3444 O  OE1 . GLU A 1 472 ? 137.723 93.889  196.441 1.00 157.19 ? 472 GLU A OE1 1 
ATOM   3445 O  OE2 . GLU A 1 472 ? 137.820 92.694  198.280 1.00 157.19 ? 472 GLU A OE2 1 
ATOM   3446 N  N   . GLU A 1 473 ? 136.177 96.424  197.398 1.00 148.42 ? 473 GLU A N   1 
ATOM   3447 C  CA  . GLU A 1 473 ? 134.869 96.248  196.771 1.00 148.42 ? 473 GLU A CA  1 
ATOM   3448 C  C   . GLU A 1 473 ? 134.118 97.572  196.678 1.00 148.42 ? 473 GLU A C   1 
ATOM   3449 O  O   . GLU A 1 473 ? 133.434 97.837  195.680 1.00 148.42 ? 473 GLU A O   1 
ATOM   3450 C  CB  . GLU A 1 473 ? 134.045 95.204  197.533 1.00 148.42 ? 473 GLU A CB  1 
ATOM   3451 C  CG  . GLU A 1 473 ? 133.826 95.487  199.016 1.00 148.42 ? 473 GLU A CG  1 
ATOM   3452 C  CD  . GLU A 1 473 ? 134.909 94.900  199.898 1.00 148.42 ? 473 GLU A CD  1 
ATOM   3453 O  OE1 . GLU A 1 473 ? 136.076 95.325  199.773 1.00 148.42 ? 473 GLU A OE1 1 
ATOM   3454 O  OE2 . GLU A 1 473 ? 134.593 94.012  200.718 1.00 148.42 ? 473 GLU A OE2 1 
ATOM   3455 N  N   . ILE A 1 474 ? 134.251 98.425  197.696 1.00 133.00 ? 474 ILE A N   1 
ATOM   3456 C  CA  . ILE A 1 474 ? 133.588 99.725  197.675 1.00 133.00 ? 474 ILE A CA  1 
ATOM   3457 C  C   . ILE A 1 474 ? 134.161 100.597 196.564 1.00 133.00 ? 474 ILE A C   1 
ATOM   3458 O  O   . ILE A 1 474 ? 133.415 101.148 195.746 1.00 133.00 ? 474 ILE A O   1 
ATOM   3459 C  CB  . ILE A 1 474 ? 133.707 100.403 199.051 1.00 133.00 ? 474 ILE A CB  1 
ATOM   3460 C  CG1 . ILE A 1 474 ? 132.975 99.579  200.114 1.00 133.00 ? 474 ILE A CG1 1 
ATOM   3461 C  CG2 . ILE A 1 474 ? 133.179 101.821 198.996 1.00 133.00 ? 474 ILE A CG2 1 
ATOM   3462 C  CD1 . ILE A 1 474 ? 132.943 100.227 201.482 1.00 133.00 ? 474 ILE A CD1 1 
ATOM   3463 N  N   . LEU A 1 475 ? 135.495 100.704 196.505 1.00 134.46 ? 475 LEU A N   1 
ATOM   3464 C  CA  . LEU A 1 475 ? 136.159 101.445 195.435 1.00 134.46 ? 475 LEU A CA  1 
ATOM   3465 C  C   . LEU A 1 475 ? 135.843 100.855 194.068 1.00 134.46 ? 475 LEU A C   1 
ATOM   3466 O  O   . LEU A 1 475 ? 135.694 101.599 193.090 1.00 134.46 ? 475 LEU A O   1 
ATOM   3467 C  CB  . LEU A 1 475 ? 137.672 101.457 195.668 1.00 134.46 ? 475 LEU A CB  1 
ATOM   3468 C  CG  . LEU A 1 475 ? 138.575 102.322 194.782 1.00 134.46 ? 475 LEU A CG  1 
ATOM   3469 C  CD1 . LEU A 1 475 ? 138.253 103.800 194.920 1.00 134.46 ? 475 LEU A CD1 1 
ATOM   3470 C  CD2 . LEU A 1 475 ? 140.040 102.060 195.102 1.00 134.46 ? 475 LEU A CD2 1 
ATOM   3471 N  N   . ALA A 1 476 ? 135.725 99.527  193.990 1.00 132.80 ? 476 ALA A N   1 
ATOM   3472 C  CA  . ALA A 1 476 ? 135.331 98.885  192.743 1.00 132.80 ? 476 ALA A CA  1 
ATOM   3473 C  C   . ALA A 1 476 ? 133.932 99.310  192.323 1.00 132.80 ? 476 ALA A C   1 
ATOM   3474 O  O   . ALA A 1 476 ? 133.681 99.534  191.136 1.00 132.80 ? 476 ALA A O   1 
ATOM   3475 C  CB  . ALA A 1 476 ? 135.412 97.366  192.887 1.00 132.80 ? 476 ALA A CB  1 
ATOM   3476 N  N   . LYS A 1 477 ? 133.006 99.436  193.279 1.00 125.26 ? 477 LYS A N   1 
ATOM   3477 C  CA  . LYS A 1 477 ? 131.654 99.850  192.910 1.00 125.26 ? 477 LYS A CA  1 
ATOM   3478 C  C   . LYS A 1 477 ? 131.630 101.316 192.484 1.00 125.26 ? 477 LYS A C   1 
ATOM   3479 O  O   . LYS A 1 477 ? 130.908 101.680 191.545 1.00 125.26 ? 477 LYS A O   1 
ATOM   3480 C  CB  . LYS A 1 477 ? 130.667 99.569  194.055 1.00 125.26 ? 477 LYS A CB  1 
ATOM   3481 C  CG  . LYS A 1 477 ? 129.536 100.598 194.292 1.00 125.26 ? 477 LYS A CG  1 
ATOM   3482 C  CD  . LYS A 1 477 ? 129.855 101.762 195.234 1.00 125.26 ? 477 LYS A CD  1 
ATOM   3483 C  CE  . LYS A 1 477 ? 130.087 101.293 196.655 1.00 125.26 ? 477 LYS A CE  1 
ATOM   3484 N  NZ  . LYS A 1 477 ? 130.303 102.454 197.557 1.00 125.26 ? 477 LYS A NZ  1 
ATOM   3485 N  N   . LEU A 1 478 ? 132.411 102.171 193.159 1.00 120.40 ? 478 LEU A N   1 
ATOM   3486 C  CA  . LEU A 1 478 ? 132.513 103.569 192.731 1.00 120.40 ? 478 LEU A CA  1 
ATOM   3487 C  C   . LEU A 1 478 ? 133.040 103.660 191.309 1.00 120.40 ? 478 LEU A C   1 
ATOM   3488 O  O   . LEU A 1 478 ? 132.504 104.404 190.480 1.00 120.40 ? 478 LEU A O   1 
ATOM   3489 C  CB  . LEU A 1 478 ? 133.429 104.378 193.647 1.00 120.40 ? 478 LEU A CB  1 
ATOM   3490 C  CG  . LEU A 1 478 ? 133.615 104.145 195.135 1.00 120.40 ? 478 LEU A CG  1 
ATOM   3491 C  CD1 . LEU A 1 478 ? 134.841 104.898 195.575 1.00 120.40 ? 478 LEU A CD1 1 
ATOM   3492 C  CD2 . LEU A 1 478 ? 132.391 104.593 195.916 1.00 120.40 ? 478 LEU A CD2 1 
ATOM   3493 N  N   . LYS A 1 479 ? 134.093 102.897 191.009 1.00 113.66 ? 479 LYS A N   1 
ATOM   3494 C  CA  . LYS A 1 479 ? 134.623 102.888 189.653 1.00 113.66 ? 479 LYS A CA  1 
ATOM   3495 C  C   . LYS A 1 479 ? 133.624 102.294 188.672 1.00 113.66 ? 479 LYS A C   1 
ATOM   3496 O  O   . LYS A 1 479 ? 133.565 102.724 187.519 1.00 113.66 ? 479 LYS A O   1 
ATOM   3497 C  CB  . LYS A 1 479 ? 135.946 102.123 189.610 1.00 113.66 ? 479 LYS A CB  1 
ATOM   3498 C  CG  . LYS A 1 479 ? 137.168 102.956 189.993 1.00 113.66 ? 479 LYS A CG  1 
ATOM   3499 C  CD  . LYS A 1 479 ? 137.079 104.386 189.469 1.00 113.66 ? 479 LYS A CD  1 
ATOM   3500 C  CE  . LYS A 1 479 ? 137.479 104.473 188.002 1.00 113.66 ? 479 LYS A CE  1 
ATOM   3501 N  NZ  . LYS A 1 479 ? 137.693 105.881 187.566 1.00 113.66 ? 479 LYS A NZ  1 
ATOM   3502 N  N   . GLU A 1 480 ? 132.814 101.330 189.115 1.00 109.30 ? 480 GLU A N   1 
ATOM   3503 C  CA  . GLU A 1 480 ? 131.813 100.734 188.237 1.00 109.30 ? 480 GLU A CA  1 
ATOM   3504 C  C   . GLU A 1 480 ? 130.775 101.764 187.813 1.00 109.30 ? 480 GLU A C   1 
ATOM   3505 O  O   . GLU A 1 480 ? 130.480 101.906 186.621 1.00 109.30 ? 480 GLU A O   1 
ATOM   3506 C  CB  . GLU A 1 480 ? 131.142 99.548  188.932 1.00 109.30 ? 480 GLU A CB  1 
ATOM   3507 C  CG  . GLU A 1 480 ? 130.386 98.625  187.990 1.00 109.30 ? 480 GLU A CG  1 
ATOM   3508 C  CD  . GLU A 1 480 ? 128.909 98.961  187.901 1.00 109.30 ? 480 GLU A CD  1 
ATOM   3509 O  OE1 . GLU A 1 480 ? 128.389 99.615  188.829 1.00 109.30 ? 480 GLU A OE1 1 
ATOM   3510 O  OE2 . GLU A 1 480 ? 128.268 98.571  186.902 1.00 109.30 ? 480 GLU A OE2 1 
ATOM   3511 N  N   . THR A 1 481 ? 130.224 102.509 188.777 1.00 106.68 ? 481 THR A N   1 
ATOM   3512 C  CA  . THR A 1 481 ? 129.300 103.584 188.411 1.00 106.68 ? 481 THR A CA  1 
ATOM   3513 C  C   . THR A 1 481 ? 129.998 104.698 187.638 1.00 106.68 ? 481 THR A C   1 
ATOM   3514 O  O   . THR A 1 481 ? 129.372 105.330 186.778 1.00 106.68 ? 481 THR A O   1 
ATOM   3515 C  CB  . THR A 1 481 ? 128.593 104.169 189.638 1.00 106.68 ? 481 THR A CB  1 
ATOM   3516 O  OG1 . THR A 1 481 ? 129.383 105.225 190.203 1.00 106.68 ? 481 THR A OG1 1 
ATOM   3517 C  CG2 . THR A 1 481 ? 128.279 103.105 190.674 1.00 106.68 ? 481 THR A CG2 1 
ATOM   3518 N  N   . ASN A 1 482 ? 131.284 104.941 187.906 1.00 101.01 ? 482 ASN A N   1 
ATOM   3519 C  CA  . ASN A 1 482 ? 132.008 105.975 187.174 1.00 101.01 ? 482 ASN A CA  1 
ATOM   3520 C  C   . ASN A 1 482 ? 132.128 105.623 185.695 1.00 101.01 ? 482 ASN A C   1 
ATOM   3521 O  O   . ASN A 1 482 ? 131.814 106.441 184.826 1.00 101.01 ? 482 ASN A O   1 
ATOM   3522 C  CB  . ASN A 1 482 ? 133.388 106.193 187.793 1.00 101.01 ? 482 ASN A CB  1 
ATOM   3523 C  CG  . ASN A 1 482 ? 134.275 107.082 186.939 1.00 101.01 ? 482 ASN A CG  1 
ATOM   3524 O  OD1 . ASN A 1 482 ? 135.356 106.677 186.512 1.00 101.01 ? 482 ASN A OD1 1 
ATOM   3525 N  ND2 . ASN A 1 482 ? 133.817 108.302 186.686 1.00 101.01 ? 482 ASN A ND2 1 
ATOM   3526 N  N   . GLU A 1 483 ? 132.553 104.394 185.386 1.00 100.19 ? 483 GLU A N   1 
ATOM   3527 C  CA  . GLU A 1 483 ? 132.641 103.993 183.983 1.00 100.19 ? 483 GLU A CA  1 
ATOM   3528 C  C   . GLU A 1 483 ? 131.261 103.773 183.371 1.00 100.19 ? 483 GLU A C   1 
ATOM   3529 O  O   . GLU A 1 483 ? 131.104 103.907 182.152 1.00 100.19 ? 483 GLU A O   1 
ATOM   3530 C  CB  . GLU A 1 483 ? 133.496 102.730 183.817 1.00 100.19 ? 483 GLU A CB  1 
ATOM   3531 C  CG  . GLU A 1 483 ? 134.733 102.641 184.702 1.00 100.19 ? 483 GLU A CG  1 
ATOM   3532 C  CD  . GLU A 1 483 ? 135.942 103.357 184.133 1.00 100.19 ? 483 GLU A CD  1 
ATOM   3533 O  OE1 . GLU A 1 483 ? 135.788 104.082 183.134 1.00 100.19 ? 483 GLU A OE1 1 
ATOM   3534 O  OE2 . GLU A 1 483 ? 137.048 103.198 184.693 1.00 100.19 ? 483 GLU A OE2 1 
ATOM   3535 N  N   . GLU A 1 484 ? 130.253 103.451 184.190 1.00 98.73  ? 484 GLU A N   1 
ATOM   3536 C  CA  . GLU A 1 484 ? 128.888 103.358 183.680 1.00 98.73  ? 484 GLU A CA  1 
ATOM   3537 C  C   . GLU A 1 484 ? 128.386 104.717 183.213 1.00 98.73  ? 484 GLU A C   1 
ATOM   3538 O  O   . GLU A 1 484 ? 127.766 104.827 182.149 1.00 98.73  ? 484 GLU A O   1 
ATOM   3539 C  CB  . GLU A 1 484 ? 127.965 102.784 184.755 1.00 98.73  ? 484 GLU A CB  1 
ATOM   3540 C  CG  . GLU A 1 484 ? 126.488 102.827 184.398 1.00 98.73  ? 484 GLU A CG  1 
ATOM   3541 C  CD  . GLU A 1 484 ? 125.592 102.602 185.599 1.00 98.73  ? 484 GLU A CD  1 
ATOM   3542 O  OE1 . GLU A 1 484 ? 126.072 102.772 186.739 1.00 98.73  ? 484 GLU A OE1 1 
ATOM   3543 O  OE2 . GLU A 1 484 ? 124.407 102.257 185.402 1.00 98.73  ? 484 GLU A OE2 1 
ATOM   3544 N  N   . PHE A 1 485 ? 128.647 105.763 183.999 1.00 92.39  ? 485 PHE A N   1 
ATOM   3545 C  CA  . PHE A 1 485 ? 128.336 107.116 183.556 1.00 92.39  ? 485 PHE A CA  1 
ATOM   3546 C  C   . PHE A 1 485 ? 129.227 107.541 182.398 1.00 92.39  ? 485 PHE A C   1 
ATOM   3547 O  O   . PHE A 1 485 ? 128.791 108.301 181.527 1.00 92.39  ? 485 PHE A O   1 
ATOM   3548 C  CB  . PHE A 1 485 ? 128.477 108.091 184.723 1.00 92.39  ? 485 PHE A CB  1 
ATOM   3549 C  CG  . PHE A 1 485 ? 127.309 108.079 185.664 1.00 92.39  ? 485 PHE A CG  1 
ATOM   3550 C  CD1 . PHE A 1 485 ? 126.032 107.813 185.199 1.00 92.39  ? 485 PHE A CD1 1 
ATOM   3551 C  CD2 . PHE A 1 485 ? 127.488 108.336 187.012 1.00 92.39  ? 485 PHE A CD2 1 
ATOM   3552 C  CE1 . PHE A 1 485 ? 124.953 107.804 186.063 1.00 92.39  ? 485 PHE A CE1 1 
ATOM   3553 C  CE2 . PHE A 1 485 ? 126.414 108.328 187.881 1.00 92.39  ? 485 PHE A CE2 1 
ATOM   3554 C  CZ  . PHE A 1 485 ? 125.145 108.061 187.405 1.00 92.39  ? 485 PHE A CZ  1 
ATOM   3555 N  N   . SER A 1 486 ? 130.470 107.058 182.373 1.00 90.05  ? 486 SER A N   1 
ATOM   3556 C  CA  . SER A 1 486 ? 131.412 107.449 181.332 1.00 90.05  ? 486 SER A CA  1 
ATOM   3557 C  C   . SER A 1 486 ? 130.980 106.934 179.965 1.00 90.05  ? 486 SER A C   1 
ATOM   3558 O  O   . SER A 1 486 ? 130.955 107.693 178.990 1.00 90.05  ? 486 SER A O   1 
ATOM   3559 C  CB  . SER A 1 486 ? 132.808 106.940 181.684 1.00 90.05  ? 486 SER A CB  1 
ATOM   3560 O  OG  . SER A 1 486 ? 133.237 107.448 182.935 1.00 90.05  ? 486 SER A OG  1 
ATOM   3561 N  N   . ASN A 1 487 ? 130.627 105.648 179.871 1.00 90.63  ? 487 ASN A N   1 
ATOM   3562 C  CA  . ASN A 1 487 ? 130.230 105.088 178.582 1.00 90.63  ? 487 ASN A CA  1 
ATOM   3563 C  C   . ASN A 1 487 ? 128.889 105.622 178.095 1.00 90.63  ? 487 ASN A C   1 
ATOM   3564 O  O   . ASN A 1 487 ? 128.545 105.409 176.928 1.00 90.63  ? 487 ASN A O   1 
ATOM   3565 C  CB  . ASN A 1 487 ? 130.191 103.557 178.638 1.00 90.63  ? 487 ASN A CB  1 
ATOM   3566 C  CG  . ASN A 1 487 ? 129.340 103.026 179.773 1.00 90.63  ? 487 ASN A CG  1 
ATOM   3567 O  OD1 . ASN A 1 487 ? 128.125 103.220 179.803 1.00 90.63  ? 487 ASN A OD1 1 
ATOM   3568 N  ND2 . ASN A 1 487 ? 129.976 102.330 180.707 1.00 90.63  ? 487 ASN A ND2 1 
ATOM   3569 N  N   . GLN A 1 488 ? 128.131 106.301 178.952 1.00 88.62  ? 488 GLN A N   1 
ATOM   3570 C  CA  . GLN A 1 488 ? 126.937 107.025 178.540 1.00 88.62  ? 488 GLN A CA  1 
ATOM   3571 C  C   . GLN A 1 488 ? 127.252 108.424 178.027 1.00 88.62  ? 488 GLN A C   1 
ATOM   3572 O  O   . GLN A 1 488 ? 126.316 109.195 177.785 1.00 88.62  ? 488 GLN A O   1 
ATOM   3573 C  CB  . GLN A 1 488 ? 125.944 107.113 179.701 1.00 88.62  ? 488 GLN A CB  1 
ATOM   3574 C  CG  . GLN A 1 488 ? 125.011 105.921 179.820 1.00 88.62  ? 488 GLN A CG  1 
ATOM   3575 C  CD  . GLN A 1 488 ? 124.336 105.845 181.176 1.00 88.62  ? 488 GLN A CD  1 
ATOM   3576 O  OE1 . GLN A 1 488 ? 123.774 106.828 181.658 1.00 88.62  ? 488 GLN A OE1 1 
ATOM   3577 N  NE2 . GLN A 1 488 ? 124.391 104.674 181.799 1.00 88.62  ? 488 GLN A NE2 1 
ATOM   3578 N  N   . ALA A 1 489 ? 128.541 108.751 177.868 1.00 73.98  ? 489 ALA A N   1 
ATOM   3579 C  CA  . ALA A 1 489 ? 129.009 110.079 177.460 1.00 73.98  ? 489 ALA A CA  1 
ATOM   3580 C  C   . ALA A 1 489 ? 128.540 111.153 178.441 1.00 73.98  ? 489 ALA A C   1 
ATOM   3581 O  O   . ALA A 1 489 ? 127.979 112.181 178.056 1.00 73.98  ? 489 ALA A O   1 
ATOM   3582 C  CB  . ALA A 1 489 ? 128.583 110.409 176.026 1.00 73.98  ? 489 ALA A CB  1 
ATOM   3583 N  N   . LEU A 1 490 ? 128.779 110.901 179.727 1.00 84.88  ? 490 LEU A N   1 
ATOM   3584 C  CA  . LEU A 1 490 ? 128.374 111.800 180.803 1.00 84.88  ? 490 LEU A CA  1 
ATOM   3585 C  C   . LEU A 1 490 ? 129.612 112.155 181.616 1.00 84.88  ? 490 LEU A C   1 
ATOM   3586 O  O   . LEU A 1 490 ? 130.170 111.292 182.301 1.00 84.88  ? 490 LEU A O   1 
ATOM   3587 C  CB  . LEU A 1 490 ? 127.327 111.145 181.707 1.00 84.88  ? 490 LEU A CB  1 
ATOM   3588 C  CG  . LEU A 1 490 ? 126.026 110.536 181.177 1.00 84.88  ? 490 LEU A CG  1 
ATOM   3589 C  CD1 . LEU A 1 490 ? 125.020 110.378 182.309 1.00 84.88  ? 490 LEU A CD1 1 
ATOM   3590 C  CD2 . LEU A 1 490 ? 125.428 111.343 180.052 1.00 84.88  ? 490 LEU A CD2 1 
ATOM   3591 N  N   . ARG A 1 491 ? 130.047 113.411 181.548 1.00 82.40  ? 491 ARG A N   1 
ATOM   3592 C  CA  . ARG A 1 491 ? 131.080 113.865 182.469 1.00 82.40  ? 491 ARG A CA  1 
ATOM   3593 C  C   . ARG A 1 491 ? 130.479 114.003 183.864 1.00 82.40  ? 491 ARG A C   1 
ATOM   3594 O  O   . ARG A 1 491 ? 129.310 114.365 184.020 1.00 82.40  ? 491 ARG A O   1 
ATOM   3595 C  CB  . ARG A 1 491 ? 131.701 115.182 181.989 1.00 82.40  ? 491 ARG A CB  1 
ATOM   3596 C  CG  . ARG A 1 491 ? 130.947 116.453 182.347 1.00 82.40  ? 491 ARG A CG  1 
ATOM   3597 C  CD  . ARG A 1 491 ? 131.673 117.682 181.821 1.00 82.40  ? 491 ARG A CD  1 
ATOM   3598 N  NE  . ARG A 1 491 ? 133.055 117.745 182.281 1.00 82.40  ? 491 ARG A NE  1 
ATOM   3599 C  CZ  . ARG A 1 491 ? 133.432 118.165 183.481 1.00 82.40  ? 491 ARG A CZ  1 
ATOM   3600 N  NH1 . ARG A 1 491 ? 132.552 118.584 184.376 1.00 82.40  ? 491 ARG A NH1 1 
ATOM   3601 N  NH2 . ARG A 1 491 ? 134.726 118.169 183.791 1.00 82.40  ? 491 ARG A NH2 1 
ATOM   3602 N  N   . VAL A 1 492 ? 131.270 113.676 184.882 1.00 88.61  ? 492 VAL A N   1 
ATOM   3603 C  CA  . VAL A 1 492 ? 130.743 113.477 186.227 1.00 88.61  ? 492 VAL A CA  1 
ATOM   3604 C  C   . VAL A 1 492 ? 131.718 114.065 187.241 1.00 88.61  ? 492 VAL A C   1 
ATOM   3605 O  O   . VAL A 1 492 ? 132.938 114.001 187.056 1.00 88.61  ? 492 VAL A O   1 
ATOM   3606 C  CB  . VAL A 1 492 ? 130.466 111.975 186.479 1.00 88.61  ? 492 VAL A CB  1 
ATOM   3607 C  CG1 . VAL A 1 492 ? 131.725 111.136 186.284 1.00 88.61  ? 492 VAL A CG1 1 
ATOM   3608 C  CG2 . VAL A 1 492 ? 129.825 111.736 187.833 1.00 88.61  ? 492 VAL A CG2 1 
ATOM   3609 N  N   . LEU A 1 493 ? 131.176 114.663 188.304 1.00 97.62  ? 493 LEU A N   1 
ATOM   3610 C  CA  . LEU A 1 493 ? 131.962 115.322 189.340 1.00 97.62  ? 493 LEU A CA  1 
ATOM   3611 C  C   . LEU A 1 493 ? 131.683 114.686 190.696 1.00 97.62  ? 493 LEU A C   1 
ATOM   3612 O  O   . LEU A 1 493 ? 130.556 114.263 190.972 1.00 97.62  ? 493 LEU A O   1 
ATOM   3613 C  CB  . LEU A 1 493 ? 131.651 116.824 189.408 1.00 97.62  ? 493 LEU A CB  1 
ATOM   3614 C  CG  . LEU A 1 493 ? 132.003 117.721 188.217 1.00 97.62  ? 493 LEU A CG  1 
ATOM   3615 C  CD1 . LEU A 1 493 ? 133.287 117.265 187.537 1.00 97.62  ? 493 LEU A CD1 1 
ATOM   3616 C  CD2 . LEU A 1 493 ? 130.852 117.794 187.222 1.00 97.62  ? 493 LEU A CD2 1 
ATOM   3617 N  N   . ALA A 1 494 ? 132.707 114.641 191.545 1.00 105.33 ? 494 ALA A N   1 
ATOM   3618 C  CA  . ALA A 1 494 ? 132.611 114.055 192.875 1.00 105.33 ? 494 ALA A CA  1 
ATOM   3619 C  C   . ALA A 1 494 ? 132.723 115.134 193.945 1.00 105.33 ? 494 ALA A C   1 
ATOM   3620 O  O   . ALA A 1 494 ? 133.348 116.178 193.737 1.00 105.33 ? 494 ALA A O   1 
ATOM   3621 C  CB  . ALA A 1 494 ? 133.693 112.995 193.090 1.00 105.33 ? 494 ALA A CB  1 
ATOM   3622 N  N   . TYR A 1 495 ? 132.115 114.864 195.100 1.00 106.95 ? 495 TYR A N   1 
ATOM   3623 C  CA  . TYR A 1 495 ? 131.934 115.859 196.149 1.00 106.95 ? 495 TYR A CA  1 
ATOM   3624 C  C   . TYR A 1 495 ? 132.282 115.265 197.509 1.00 106.95 ? 495 TYR A C   1 
ATOM   3625 O  O   . TYR A 1 495 ? 132.250 114.048 197.704 1.00 106.95 ? 495 TYR A O   1 
ATOM   3626 C  CB  . TYR A 1 495 ? 130.498 116.396 196.147 1.00 106.95 ? 495 TYR A CB  1 
ATOM   3627 C  CG  . TYR A 1 495 ? 129.964 116.717 194.770 1.00 106.95 ? 495 TYR A CG  1 
ATOM   3628 C  CD1 . TYR A 1 495 ? 130.551 117.708 193.993 1.00 106.95 ? 495 TYR A CD1 1 
ATOM   3629 C  CD2 . TYR A 1 495 ? 128.883 116.028 194.243 1.00 106.95 ? 495 TYR A CD2 1 
ATOM   3630 C  CE1 . TYR A 1 495 ? 130.073 118.007 192.734 1.00 106.95 ? 495 TYR A CE1 1 
ATOM   3631 C  CE2 . TYR A 1 495 ? 128.399 116.320 192.983 1.00 106.95 ? 495 TYR A CE2 1 
ATOM   3632 C  CZ  . TYR A 1 495 ? 128.996 117.310 192.233 1.00 106.95 ? 495 TYR A CZ  1 
ATOM   3633 O  OH  . TYR A 1 495 ? 128.515 117.603 190.978 1.00 106.95 ? 495 TYR A OH  1 
ATOM   3634 N  N   . GLY A 1 496 ? 132.614 116.143 198.452 1.00 119.00 ? 496 GLY A N   1 
ATOM   3635 C  CA  . GLY A 1 496 ? 133.045 115.708 199.771 1.00 119.00 ? 496 GLY A CA  1 
ATOM   3636 C  C   . GLY A 1 496 ? 132.638 116.668 200.867 1.00 119.00 ? 496 GLY A C   1 
ATOM   3637 O  O   . GLY A 1 496 ? 132.557 117.882 200.656 1.00 119.00 ? 496 GLY A O   1 
ATOM   3638 N  N   . TYR A 1 497 ? 132.416 116.118 202.064 1.00 130.32 ? 497 TYR A N   1 
ATOM   3639 C  CA  . TYR A 1 497 ? 131.881 116.876 203.190 1.00 130.32 ? 497 TYR A CA  1 
ATOM   3640 C  C   . TYR A 1 497 ? 132.739 116.820 204.449 1.00 130.32 ? 497 TYR A C   1 
ATOM   3641 O  O   . TYR A 1 497 ? 132.758 117.796 205.202 1.00 130.32 ? 497 TYR A O   1 
ATOM   3642 C  CB  . TYR A 1 497 ? 130.465 116.373 203.538 1.00 130.32 ? 497 TYR A CB  1 
ATOM   3643 C  CG  . TYR A 1 497 ? 129.518 117.428 204.082 1.00 130.32 ? 497 TYR A CG  1 
ATOM   3644 C  CD1 . TYR A 1 497 ? 129.692 117.971 205.350 1.00 130.32 ? 497 TYR A CD1 1 
ATOM   3645 C  CD2 . TYR A 1 497 ? 128.432 117.860 203.332 1.00 130.32 ? 497 TYR A CD2 1 
ATOM   3646 C  CE1 . TYR A 1 497 ? 128.828 118.931 205.844 1.00 130.32 ? 497 TYR A CE1 1 
ATOM   3647 C  CE2 . TYR A 1 497 ? 127.565 118.823 203.816 1.00 130.32 ? 497 TYR A CE2 1 
ATOM   3648 C  CZ  . TYR A 1 497 ? 127.765 119.350 205.074 1.00 130.32 ? 497 TYR A CZ  1 
ATOM   3649 O  OH  . TYR A 1 497 ? 126.900 120.303 205.561 1.00 130.32 ? 497 TYR A OH  1 
ATOM   3650 N  N   . LYS A 1 498 ? 133.457 115.721 204.686 1.00 137.87 ? 498 LYS A N   1 
ATOM   3651 C  CA  . LYS A 1 498 ? 134.046 115.442 205.993 1.00 137.87 ? 498 LYS A CA  1 
ATOM   3652 C  C   . LYS A 1 498 ? 135.124 116.458 206.353 1.00 137.87 ? 498 LYS A C   1 
ATOM   3653 O  O   . LYS A 1 498 ? 135.936 116.855 205.513 1.00 137.87 ? 498 LYS A O   1 
ATOM   3654 C  CB  . LYS A 1 498 ? 134.624 114.025 206.014 1.00 137.87 ? 498 LYS A CB  1 
ATOM   3655 C  CG  . LYS A 1 498 ? 135.598 113.721 207.142 1.00 137.87 ? 498 LYS A CG  1 
ATOM   3656 C  CD  . LYS A 1 498 ? 134.855 113.264 208.387 1.00 137.87 ? 498 LYS A CD  1 
ATOM   3657 C  CE  . LYS A 1 498 ? 135.662 112.242 209.170 1.00 137.87 ? 498 LYS A CE  1 
ATOM   3658 N  NZ  . LYS A 1 498 ? 135.421 110.855 208.684 1.00 137.87 ? 498 LYS A NZ  1 
ATOM   3659 N  N   . ARG A 1 499 ? 135.120 116.879 207.617 1.00 153.45 ? 499 ARG A N   1 
ATOM   3660 C  CA  . ARG A 1 499 ? 136.001 117.936 208.083 1.00 153.45 ? 499 ARG A CA  1 
ATOM   3661 C  C   . ARG A 1 499 ? 136.264 117.759 209.571 1.00 153.45 ? 499 ARG A C   1 
ATOM   3662 O  O   . ARG A 1 499 ? 135.505 117.096 210.282 1.00 153.45 ? 499 ARG A O   1 
ATOM   3663 C  CB  . ARG A 1 499 ? 135.383 119.311 207.822 1.00 153.45 ? 499 ARG A CB  1 
ATOM   3664 C  CG  . ARG A 1 499 ? 133.912 119.386 208.220 1.00 153.45 ? 499 ARG A CG  1 
ATOM   3665 C  CD  . ARG A 1 499 ? 133.727 120.096 209.553 1.00 153.45 ? 499 ARG A CD  1 
ATOM   3666 N  NE  . ARG A 1 499 ? 132.362 119.999 210.056 1.00 153.45 ? 499 ARG A NE  1 
ATOM   3667 C  CZ  . ARG A 1 499 ? 131.922 120.616 211.143 1.00 153.45 ? 499 ARG A CZ  1 
ATOM   3668 N  NH1 . ARG A 1 499 ? 132.712 121.395 211.863 1.00 153.45 ? 499 ARG A NH1 1 
ATOM   3669 N  NH2 . ARG A 1 499 ? 130.658 120.446 211.520 1.00 153.45 ? 499 ARG A NH2 1 
ATOM   3670 N  N   . MET A 1 500 ? 137.356 118.365 210.034 1.00 166.10 ? 500 MET A N   1 
ATOM   3671 C  CA  . MET A 1 500 ? 137.559 118.514 211.465 1.00 166.10 ? 500 MET A CA  1 
ATOM   3672 C  C   . MET A 1 500 ? 136.736 119.695 211.979 1.00 166.10 ? 500 MET A C   1 
ATOM   3673 O  O   . MET A 1 500 ? 136.455 120.632 211.227 1.00 166.10 ? 500 MET A O   1 
ATOM   3674 C  CB  . MET A 1 500 ? 139.034 118.733 211.780 1.00 166.10 ? 500 MET A CB  1 
ATOM   3675 N  N   . PRO A 1 501 ? 136.293 119.679 213.254 1.00 173.38 ? 501 PRO A N   1 
ATOM   3676 C  CA  . PRO A 1 501 ? 135.562 120.833 213.782 1.00 173.38 ? 501 PRO A CA  1 
ATOM   3677 C  C   . PRO A 1 501 ? 136.423 122.100 213.704 1.00 173.38 ? 501 PRO A C   1 
ATOM   3678 O  O   . PRO A 1 501 ? 136.037 123.016 212.998 1.00 173.38 ? 501 PRO A O   1 
ATOM   3679 C  CB  . PRO A 1 501 ? 135.309 120.461 215.247 1.00 173.38 ? 501 PRO A CB  1 
ATOM   3680 N  N   . ALA A 1 502 ? 137.543 122.124 214.436 1.00 173.10 ? 502 ALA A N   1 
ATOM   3681 C  CA  . ALA A 1 502 ? 138.454 123.294 214.419 1.00 173.10 ? 502 ALA A CA  1 
ATOM   3682 C  C   . ALA A 1 502 ? 137.654 124.599 214.485 1.00 173.10 ? 502 ALA A C   1 
ATOM   3683 O  O   . ALA A 1 502 ? 136.751 124.700 215.342 1.00 173.10 ? 502 ALA A O   1 
ATOM   3684 C  CB  . ALA A 1 502 ? 139.328 123.241 213.188 1.00 173.10 ? 502 ALA A CB  1 
ATOM   3685 N  N   . ASP A 1 503 ? 137.979 125.562 213.617 1.00 168.16 ? 503 ASP A N   1 
ATOM   3686 C  CA  . ASP A 1 503 ? 137.275 126.872 213.596 1.00 168.16 ? 503 ASP A CA  1 
ATOM   3687 C  C   . ASP A 1 503 ? 137.552 127.550 212.250 1.00 168.16 ? 503 ASP A C   1 
ATOM   3688 O  O   . ASP A 1 503 ? 137.991 126.848 211.319 1.00 168.16 ? 503 ASP A O   1 
ATOM   3689 C  CB  . ASP A 1 503 ? 137.707 127.763 214.761 1.00 168.16 ? 503 ASP A CB  1 
ATOM   3690 N  N   . THR A 1 504 ? 137.317 128.862 212.156 1.00 169.37 ? 504 THR A N   1 
ATOM   3691 C  CA  . THR A 1 504 ? 137.523 129.538 210.878 1.00 169.37 ? 504 THR A CA  1 
ATOM   3692 C  C   . THR A 1 504 ? 139.002 129.488 210.515 1.00 169.37 ? 504 THR A C   1 
ATOM   3693 O  O   . THR A 1 504 ? 139.825 130.180 211.123 1.00 169.37 ? 504 THR A O   1 
ATOM   3694 C  CB  . THR A 1 504 ? 137.029 130.980 210.954 1.00 169.37 ? 504 THR A CB  1 
ATOM   3695 N  N   . THR A 1 505 ? 139.343 128.670 209.523 1.00 163.19 ? 505 THR A N   1 
ATOM   3696 C  CA  . THR A 1 505 ? 140.727 128.445 209.138 1.00 163.19 ? 505 THR A CA  1 
ATOM   3697 C  C   . THR A 1 505 ? 141.210 129.576 208.229 1.00 163.19 ? 505 THR A C   1 
ATOM   3698 O  O   . THR A 1 505 ? 140.531 130.588 208.037 1.00 163.19 ? 505 THR A O   1 
ATOM   3699 C  CB  . THR A 1 505 ? 140.874 127.082 208.466 1.00 163.19 ? 505 THR A CB  1 
ATOM   3700 N  N   . GLU A 1 506 ? 142.405 129.410 207.658 1.00 167.59 ? 506 GLU A N   1 
ATOM   3701 C  CA  . GLU A 1 506 ? 143.001 130.398 206.766 1.00 167.59 ? 506 GLU A CA  1 
ATOM   3702 C  C   . GLU A 1 506 ? 142.680 130.134 205.300 1.00 167.59 ? 506 GLU A C   1 
ATOM   3703 O  O   . GLU A 1 506 ? 143.453 130.544 204.421 1.00 167.59 ? 506 GLU A O   1 
ATOM   3704 C  CB  . GLU A 1 506 ? 144.515 130.449 206.978 1.00 167.59 ? 506 GLU A CB  1 
ATOM   3705 N  N   . LEU A 1 507 ? 141.571 129.448 205.019 1.00 163.71 ? 507 LEU A N   1 
ATOM   3706 C  CA  . LEU A 1 507 ? 141.110 129.092 203.678 1.00 163.71 ? 507 LEU A CA  1 
ATOM   3707 C  C   . LEU A 1 507 ? 142.122 128.256 202.905 1.00 163.71 ? 507 LEU A C   1 
ATOM   3708 O  O   . LEU A 1 507 ? 142.132 128.290 201.668 1.00 163.71 ? 507 LEU A O   1 
ATOM   3709 C  CB  . LEU A 1 507 ? 140.727 130.335 202.861 1.00 163.71 ? 507 LEU A CB  1 
ATOM   3710 N  N   . LYS A 1 508 ? 142.975 127.506 203.597 1.00 159.24 ? 508 LYS A N   1 
ATOM   3711 C  CA  . LYS A 1 508 ? 143.994 126.693 202.954 1.00 159.24 ? 508 LYS A CA  1 
ATOM   3712 C  C   . LYS A 1 508 ? 143.488 125.260 202.794 1.00 159.24 ? 508 LYS A C   1 
ATOM   3713 O  O   . LYS A 1 508 ? 142.320 124.954 203.048 1.00 159.24 ? 508 LYS A O   1 
ATOM   3714 C  CB  . LYS A 1 508 ? 145.295 126.753 203.752 1.00 159.24 ? 508 LYS A CB  1 
ATOM   3715 N  N   . LEU A 1 509 ? 144.376 124.363 202.361 1.00 148.37 ? 509 LEU A N   1 
ATOM   3716 C  CA  . LEU A 1 509 ? 144.007 122.964 202.179 1.00 148.37 ? 509 LEU A CA  1 
ATOM   3717 C  C   . LEU A 1 509 ? 143.783 122.247 203.504 1.00 148.37 ? 509 LEU A C   1 
ATOM   3718 O  O   . LEU A 1 509 ? 142.872 121.416 203.602 1.00 148.37 ? 509 LEU A O   1 
ATOM   3719 C  CB  . LEU A 1 509 ? 145.084 122.241 201.368 1.00 148.37 ? 509 LEU A CB  1 
ATOM   3720 N  N   . GLU A 1 510 ? 144.592 122.564 204.522 1.00 146.18 ? 510 GLU A N   1 
ATOM   3721 C  CA  . GLU A 1 510 ? 144.564 121.917 205.833 1.00 146.18 ? 510 GLU A CA  1 
ATOM   3722 C  C   . GLU A 1 510 ? 144.729 120.406 205.711 1.00 146.18 ? 510 GLU A C   1 
ATOM   3723 O  O   . GLU A 1 510 ? 145.793 119.923 205.312 1.00 146.18 ? 510 GLU A O   1 
ATOM   3724 C  CB  . GLU A 1 510 ? 143.273 122.260 206.585 1.00 146.18 ? 510 GLU A CB  1 
ATOM   3725 N  N   . ASP A 1 511 ? 143.685 119.653 206.052 1.00 138.88 ? 511 ASP A N   1 
ATOM   3726 C  CA  . ASP A 1 511 ? 143.697 118.196 205.975 1.00 138.88 ? 511 ASP A CA  1 
ATOM   3727 C  C   . ASP A 1 511 ? 142.907 117.778 204.741 1.00 138.88 ? 511 ASP A C   1 
ATOM   3728 O  O   . ASP A 1 511 ? 141.672 117.839 204.738 1.00 138.88 ? 511 ASP A O   1 
ATOM   3729 C  CB  . ASP A 1 511 ? 143.111 117.576 207.242 1.00 138.88 ? 511 ASP A CB  1 
ATOM   3730 N  N   . GLU A 1 512 ? 143.617 117.352 203.696 1.00 137.25 ? 512 GLU A N   1 
ATOM   3731 C  CA  . GLU A 1 512 ? 143.002 116.978 202.429 1.00 137.25 ? 512 GLU A CA  1 
ATOM   3732 C  C   . GLU A 1 512 ? 143.155 115.490 202.127 1.00 137.25 ? 512 GLU A C   1 
ATOM   3733 O  O   . GLU A 1 512 ? 143.115 115.080 200.964 1.00 137.25 ? 512 GLU A O   1 
ATOM   3734 C  CB  . GLU A 1 512 ? 143.577 117.813 201.287 1.00 137.25 ? 512 GLU A CB  1 
ATOM   3735 C  CG  . GLU A 1 512 ? 143.016 119.221 201.207 1.00 137.25 ? 512 GLU A CG  1 
ATOM   3736 C  CD  . GLU A 1 512 ? 141.500 119.253 201.137 1.00 137.25 ? 512 GLU A CD  1 
ATOM   3737 O  OE1 . GLU A 1 512 ? 140.908 118.415 200.423 1.00 137.25 ? 512 GLU A OE1 1 
ATOM   3738 O  OE2 . GLU A 1 512 ? 140.897 120.120 201.802 1.00 137.25 ? 512 GLU A OE2 1 
ATOM   3739 N  N   . GLN A 1 513 ? 143.335 114.672 203.161 1.00 136.02 ? 513 GLN A N   1 
ATOM   3740 C  CA  . GLN A 1 513 ? 143.373 113.227 203.006 1.00 136.02 ? 513 GLN A CA  1 
ATOM   3741 C  C   . GLN A 1 513 ? 142.247 112.523 203.748 1.00 136.02 ? 513 GLN A C   1 
ATOM   3742 O  O   . GLN A 1 513 ? 142.175 111.289 203.708 1.00 136.02 ? 513 GLN A O   1 
ATOM   3743 C  CB  . GLN A 1 513 ? 144.726 112.672 203.471 1.00 136.02 ? 513 GLN A CB  1 
ATOM   3744 C  CG  . GLN A 1 513 ? 145.917 113.233 202.709 1.00 136.02 ? 513 GLN A CG  1 
ATOM   3745 C  CD  . GLN A 1 513 ? 145.774 113.072 201.207 1.00 136.02 ? 513 GLN A CD  1 
ATOM   3746 O  OE1 . GLN A 1 513 ? 145.830 114.047 200.457 1.00 136.02 ? 513 GLN A OE1 1 
ATOM   3747 N  NE2 . GLN A 1 513 ? 145.588 111.835 200.760 1.00 136.02 ? 513 GLN A NE2 1 
ATOM   3748 N  N   . ASP A 1 514 ? 141.363 113.268 204.421 1.00 133.71 ? 514 ASP A N   1 
ATOM   3749 C  CA  . ASP A 1 514 ? 140.216 112.703 205.135 1.00 133.71 ? 514 ASP A CA  1 
ATOM   3750 C  C   . ASP A 1 514 ? 138.951 113.447 204.703 1.00 133.71 ? 514 ASP A C   1 
ATOM   3751 O  O   . ASP A 1 514 ? 138.493 114.380 205.365 1.00 133.71 ? 514 ASP A O   1 
ATOM   3752 C  CB  . ASP A 1 514 ? 140.442 112.763 206.654 1.00 133.71 ? 514 ASP A CB  1 
ATOM   3753 C  CG  . ASP A 1 514 ? 141.046 114.083 207.112 1.00 133.71 ? 514 ASP A CG  1 
ATOM   3754 O  OD1 . ASP A 1 514 ? 141.579 114.126 208.241 1.00 133.71 ? 514 ASP A OD1 1 
ATOM   3755 O  OD2 . ASP A 1 514 ? 141.014 115.068 206.346 1.00 133.71 ? 514 ASP A OD2 1 
ATOM   3756 N  N   . ILE A 1 515 ? 138.373 113.011 203.584 1.00 128.07 ? 515 ILE A N   1 
ATOM   3757 C  CA  . ILE A 1 515 ? 137.139 113.576 203.051 1.00 128.07 ? 515 ILE A CA  1 
ATOM   3758 C  C   . ILE A 1 515 ? 136.179 112.430 202.763 1.00 128.07 ? 515 ILE A C   1 
ATOM   3759 O  O   . ILE A 1 515 ? 136.593 111.372 202.276 1.00 128.07 ? 515 ILE A O   1 
ATOM   3760 C  CB  . ILE A 1 515 ? 137.378 114.414 201.773 1.00 128.07 ? 515 ILE A CB  1 
ATOM   3761 C  CG1 . ILE A 1 515 ? 138.651 115.257 201.884 1.00 128.07 ? 515 ILE A CG1 1 
ATOM   3762 C  CG2 . ILE A 1 515 ? 136.197 115.326 201.514 1.00 128.07 ? 515 ILE A CG2 1 
ATOM   3763 C  CD1 . ILE A 1 515 ? 139.811 114.725 201.076 1.00 128.07 ? 515 ILE A CD1 1 
ATOM   3764 N  N   . VAL A 1 516 ? 134.900 112.630 203.082 1.00 130.32 ? 516 VAL A N   1 
ATOM   3765 C  CA  . VAL A 1 516 ? 133.902 111.609 202.798 1.00 130.32 ? 516 VAL A CA  1 
ATOM   3766 C  C   . VAL A 1 516 ? 133.438 111.778 201.354 1.00 130.32 ? 516 VAL A C   1 
ATOM   3767 O  O   . VAL A 1 516 ? 133.703 112.793 200.709 1.00 130.32 ? 516 VAL A O   1 
ATOM   3768 C  CB  . VAL A 1 516 ? 132.727 111.695 203.801 1.00 130.32 ? 516 VAL A CB  1 
ATOM   3769 C  CG1 . VAL A 1 516 ? 131.985 113.017 203.690 1.00 130.32 ? 516 VAL A CG1 1 
ATOM   3770 C  CG2 . VAL A 1 516 ? 131.814 110.464 203.788 1.00 130.32 ? 516 VAL A CG2 1 
ATOM   3771 N  N   . LEU A 1 517 ? 132.761 110.767 200.826 1.00 124.59 ? 517 LEU A N   1 
ATOM   3772 C  CA  . LEU A 1 517 ? 132.402 110.719 199.414 1.00 124.59 ? 517 LEU A CA  1 
ATOM   3773 C  C   . LEU A 1 517 ? 130.886 110.854 199.300 1.00 124.59 ? 517 LEU A C   1 
ATOM   3774 O  O   . LEU A 1 517 ? 130.145 109.897 199.541 1.00 124.59 ? 517 LEU A O   1 
ATOM   3775 C  CB  . LEU A 1 517 ? 132.935 109.431 198.793 1.00 124.59 ? 517 LEU A CB  1 
ATOM   3776 C  CG  . LEU A 1 517 ? 133.039 109.169 197.289 1.00 124.59 ? 517 LEU A CG  1 
ATOM   3777 C  CD1 . LEU A 1 517 ? 133.728 107.855 197.144 1.00 124.59 ? 517 LEU A CD1 1 
ATOM   3778 C  CD2 . LEU A 1 517 ? 131.706 109.087 196.579 1.00 124.59 ? 517 LEU A CD2 1 
ATOM   3779 N  N   . VAL A 1 518 ? 130.435 112.053 198.934 1.00 116.61 ? 518 VAL A N   1 
ATOM   3780 C  CA  . VAL A 1 518 ? 129.030 112.317 198.646 1.00 116.61 ? 518 VAL A CA  1 
ATOM   3781 C  C   . VAL A 1 518 ? 128.761 111.847 197.222 1.00 116.61 ? 518 VAL A C   1 
ATOM   3782 O  O   . VAL A 1 518 ? 129.699 111.574 196.466 1.00 116.61 ? 518 VAL A O   1 
ATOM   3783 C  CB  . VAL A 1 518 ? 128.690 113.808 198.832 1.00 116.61 ? 518 VAL A CB  1 
ATOM   3784 C  CG1 . VAL A 1 518 ? 127.253 114.098 198.411 1.00 116.61 ? 518 VAL A CG1 1 
ATOM   3785 C  CG2 . VAL A 1 518 ? 128.918 114.225 200.274 1.00 116.61 ? 518 VAL A CG2 1 
ATOM   3786 N  N   . GLY A 1 519 ? 127.488 111.761 196.844 1.00 109.53 ? 519 GLY A N   1 
ATOM   3787 C  CA  . GLY A 1 519 ? 127.104 111.130 195.595 1.00 109.53 ? 519 GLY A CA  1 
ATOM   3788 C  C   . GLY A 1 519 ? 127.634 111.846 194.364 1.00 109.53 ? 519 GLY A C   1 
ATOM   3789 O  O   . GLY A 1 519 ? 128.125 112.974 194.402 1.00 109.53 ? 519 GLY A O   1 
ATOM   3790 N  N   . LEU A 1 520 ? 127.518 111.150 193.236 1.00 105.59 ? 520 LEU A N   1 
ATOM   3791 C  CA  . LEU A 1 520 ? 128.114 111.560 191.971 1.00 105.59 ? 520 LEU A CA  1 
ATOM   3792 C  C   . LEU A 1 520 ? 127.007 111.966 191.008 1.00 105.59 ? 520 LEU A C   1 
ATOM   3793 O  O   . LEU A 1 520 ? 126.031 111.228 190.840 1.00 105.59 ? 520 LEU A O   1 
ATOM   3794 C  CB  . LEU A 1 520 ? 128.937 110.417 191.367 1.00 105.59 ? 520 LEU A CB  1 
ATOM   3795 C  CG  . LEU A 1 520 ? 130.408 110.169 191.739 1.00 105.59 ? 520 LEU A CG  1 
ATOM   3796 C  CD1 . LEU A 1 520 ? 131.347 111.107 191.016 1.00 105.59 ? 520 LEU A CD1 1 
ATOM   3797 C  CD2 . LEU A 1 520 ? 130.647 110.242 193.242 1.00 105.59 ? 520 LEU A CD2 1 
ATOM   3798 N  N   . THR A 1 521 ? 127.156 113.131 190.380 1.00 100.78 ? 521 THR A N   1 
ATOM   3799 C  CA  . THR A 1 521 ? 126.205 113.624 189.389 1.00 100.78 ? 521 THR A CA  1 
ATOM   3800 C  C   . THR A 1 521 ? 126.890 113.721 188.033 1.00 100.78 ? 521 THR A C   1 
ATOM   3801 O  O   . THR A 1 521 ? 127.925 114.382 187.903 1.00 100.78 ? 521 THR A O   1 
ATOM   3802 C  CB  . THR A 1 521 ? 125.636 114.990 189.784 1.00 100.78 ? 521 THR A CB  1 
ATOM   3803 O  OG1 . THR A 1 521 ? 126.481 116.029 189.273 1.00 100.78 ? 521 THR A OG1 1 
ATOM   3804 C  CG2 . THR A 1 521 ? 125.533 115.118 191.292 1.00 100.78 ? 521 THR A CG2 1 
ATOM   3805 N  N   . ALA A 1 522 ? 126.300 113.079 187.025 1.00 89.98  ? 522 ALA A N   1 
ATOM   3806 C  CA  . ALA A 1 522 ? 126.897 112.956 185.699 1.00 89.98  ? 522 ALA A CA  1 
ATOM   3807 C  C   . ALA A 1 522 ? 126.070 113.747 184.692 1.00 89.98  ? 522 ALA A C   1 
ATOM   3808 O  O   . ALA A 1 522 ? 124.897 113.436 184.464 1.00 89.98  ? 522 ALA A O   1 
ATOM   3809 C  CB  . ALA A 1 522 ? 126.993 111.489 185.293 1.00 89.98  ? 522 ALA A CB  1 
ATOM   3810 N  N   . MET A 1 523 ? 126.696 114.733 184.057 1.00 82.31  ? 523 MET A N   1 
ATOM   3811 C  CA  . MET A 1 523 ? 126.010 115.659 183.165 1.00 82.31  ? 523 MET A CA  1 
ATOM   3812 C  C   . MET A 1 523 ? 126.292 115.302 181.712 1.00 82.31  ? 523 MET A C   1 
ATOM   3813 O  O   . MET A 1 523 ? 127.445 115.060 181.339 1.00 82.31  ? 523 MET A O   1 
ATOM   3814 C  CB  . MET A 1 523 ? 126.439 117.098 183.449 1.00 82.31  ? 523 MET A CB  1 
ATOM   3815 C  CG  . MET A 1 523 ? 127.162 117.279 184.773 1.00 82.31  ? 523 MET A CG  1 
ATOM   3816 S  SD  . MET A 1 523 ? 127.364 119.011 185.223 1.00 82.31  ? 523 MET A SD  1 
ATOM   3817 C  CE  . MET A 1 523 ? 128.538 119.536 183.981 1.00 82.31  ? 523 MET A CE  1 
ATOM   3818 N  N   . ILE A 1 524 ? 125.239 115.267 180.899 1.00 77.15  ? 524 ILE A N   1 
ATOM   3819 C  CA  . ILE A 1 524 ? 125.375 114.932 179.487 1.00 77.15  ? 524 ILE A CA  1 
ATOM   3820 C  C   . ILE A 1 524 ? 125.955 116.133 178.756 1.00 77.15  ? 524 ILE A C   1 
ATOM   3821 O  O   . ILE A 1 524 ? 125.685 117.289 179.106 1.00 77.15  ? 524 ILE A O   1 
ATOM   3822 C  CB  . ILE A 1 524 ? 124.018 114.497 178.894 1.00 77.15  ? 524 ILE A CB  1 
ATOM   3823 C  CG1 . ILE A 1 524 ? 124.148 114.103 177.419 1.00 77.15  ? 524 ILE A CG1 1 
ATOM   3824 C  CG2 . ILE A 1 524 ? 122.993 115.606 179.000 1.00 77.15  ? 524 ILE A CG2 1 
ATOM   3825 C  CD1 . ILE A 1 524 ? 122.848 113.632 176.790 1.00 77.15  ? 524 ILE A CD1 1 
ATOM   3826 N  N   . ASP A 1 525 ? 126.798 115.866 177.764 1.00 69.51  ? 525 ASP A N   1 
ATOM   3827 C  CA  . ASP A 1 525 ? 127.363 116.931 176.957 1.00 69.51  ? 525 ASP A CA  1 
ATOM   3828 C  C   . ASP A 1 525 ? 126.661 116.948 175.610 1.00 69.51  ? 525 ASP A C   1 
ATOM   3829 O  O   . ASP A 1 525 ? 126.969 116.107 174.752 1.00 69.51  ? 525 ASP A O   1 
ATOM   3830 C  CB  . ASP A 1 525 ? 128.862 116.719 176.785 1.00 69.51  ? 525 ASP A CB  1 
ATOM   3831 C  CG  . ASP A 1 525 ? 129.659 117.948 177.131 1.00 69.51  ? 525 ASP A CG  1 
ATOM   3832 O  OD1 . ASP A 1 525 ? 129.054 118.974 177.472 1.00 69.51  ? 525 ASP A OD1 1 
ATOM   3833 O  OD2 . ASP A 1 525 ? 130.894 117.871 177.135 1.00 69.51  ? 525 ASP A OD2 1 
ATOM   3834 N  N   . PRO A 1 526 ? 125.728 117.865 175.375 1.00 60.95  ? 526 PRO A N   1 
ATOM   3835 C  CA  . PRO A 1 526 ? 124.920 117.808 174.160 1.00 60.95  ? 526 PRO A CA  1 
ATOM   3836 C  C   . PRO A 1 526 ? 125.614 118.506 173.004 1.00 60.95  ? 526 PRO A C   1 
ATOM   3837 O  O   . PRO A 1 526 ? 126.088 119.644 173.143 1.00 60.95  ? 526 PRO A O   1 
ATOM   3838 C  CB  . PRO A 1 526 ? 123.629 118.535 174.563 1.00 60.95  ? 526 PRO A CB  1 
ATOM   3839 C  CG  . PRO A 1 526 ? 124.049 119.488 175.634 1.00 60.95  ? 526 PRO A CG  1 
ATOM   3840 C  CD  . PRO A 1 526 ? 125.293 118.939 176.287 1.00 60.95  ? 526 PRO A CD  1 
ATOM   3841 N  N   . PRO A 1 527 ? 125.704 117.854 171.849 1.00 56.57  ? 527 PRO A N   1 
ATOM   3842 C  CA  . PRO A 1 527 ? 126.268 118.517 170.670 1.00 56.57  ? 527 PRO A CA  1 
ATOM   3843 C  C   . PRO A 1 527 ? 125.339 119.594 170.133 1.00 56.57  ? 527 PRO A C   1 
ATOM   3844 O  O   . PRO A 1 527 ? 124.133 119.606 170.389 1.00 56.57  ? 527 PRO A O   1 
ATOM   3845 C  CB  . PRO A 1 527 ? 126.433 117.375 169.663 1.00 56.57  ? 527 PRO A CB  1 
ATOM   3846 C  CG  . PRO A 1 527 ? 125.450 116.347 170.094 1.00 56.57  ? 527 PRO A CG  1 
ATOM   3847 C  CD  . PRO A 1 527 ? 125.386 116.441 171.589 1.00 56.57  ? 527 PRO A CD  1 
ATOM   3848 N  N   . ARG A 1 528 ? 125.934 120.519 169.383 1.00 57.54  ? 528 ARG A N   1 
ATOM   3849 C  CA  . ARG A 1 528 ? 125.178 121.560 168.703 1.00 57.54  ? 528 ARG A CA  1 
ATOM   3850 C  C   . ARG A 1 528 ? 124.271 120.941 167.638 1.00 57.54  ? 528 ARG A C   1 
ATOM   3851 O  O   . ARG A 1 528 ? 124.422 119.777 167.255 1.00 57.54  ? 528 ARG A O   1 
ATOM   3852 C  CB  . ARG A 1 528 ? 126.133 122.579 168.073 1.00 57.54  ? 528 ARG A CB  1 
ATOM   3853 C  CG  . ARG A 1 528 ? 125.552 123.965 167.823 1.00 57.54  ? 528 ARG A CG  1 
ATOM   3854 C  CD  . ARG A 1 528 ? 125.721 124.872 169.027 1.00 57.54  ? 528 ARG A CD  1 
ATOM   3855 N  NE  . ARG A 1 528 ? 127.122 125.042 169.396 1.00 57.54  ? 528 ARG A NE  1 
ATOM   3856 C  CZ  . ARG A 1 528 ? 127.795 126.177 169.277 1.00 57.54  ? 528 ARG A CZ  1 
ATOM   3857 N  NH1 . ARG A 1 528 ? 127.229 127.270 168.790 1.00 57.54  ? 528 ARG A NH1 1 
ATOM   3858 N  NH2 . ARG A 1 528 ? 129.069 126.218 169.655 1.00 57.54  ? 528 ARG A NH2 1 
ATOM   3859 N  N   . GLU A 1 529 ? 123.299 121.724 167.180 1.00 68.48  ? 529 GLU A N   1 
ATOM   3860 C  CA  . GLU A 1 529 ? 122.407 121.252 166.132 1.00 68.48  ? 529 GLU A CA  1 
ATOM   3861 C  C   . GLU A 1 529 ? 123.178 121.049 164.831 1.00 68.48  ? 529 GLU A C   1 
ATOM   3862 O  O   . GLU A 1 529 ? 124.154 121.751 164.543 1.00 68.48  ? 529 GLU A O   1 
ATOM   3863 C  CB  . GLU A 1 529 ? 121.238 122.227 165.938 1.00 68.48  ? 529 GLU A CB  1 
ATOM   3864 C  CG  . GLU A 1 529 ? 121.329 123.159 164.732 1.00 68.48  ? 529 GLU A CG  1 
ATOM   3865 C  CD  . GLU A 1 529 ? 122.254 124.344 164.957 1.00 68.48  ? 529 GLU A CD  1 
ATOM   3866 O  OE1 . GLU A 1 529 ? 122.833 124.459 166.057 1.00 68.48  ? 529 GLU A OE1 1 
ATOM   3867 O  OE2 . GLU A 1 529 ? 122.400 125.164 164.027 1.00 68.48  ? 529 GLU A OE2 1 
ATOM   3868 N  N   . ALA A 1 530 ? 122.760 120.030 164.075 1.00 62.22  ? 530 ALA A N   1 
ATOM   3869 C  CA  . ALA A 1 530 ? 123.370 119.619 162.808 1.00 62.22  ? 530 ALA A CA  1 
ATOM   3870 C  C   . ALA A 1 530 ? 124.841 119.234 162.954 1.00 62.22  ? 530 ALA A C   1 
ATOM   3871 O  O   . ALA A 1 530 ? 125.588 119.254 161.971 1.00 62.22  ? 530 ALA A O   1 
ATOM   3872 C  CB  . ALA A 1 530 ? 123.210 120.698 161.729 1.00 62.22  ? 530 ALA A CB  1 
ATOM   3873 N  N   . VAL A 1 531 ? 125.281 118.885 164.166 1.00 56.30  ? 531 VAL A N   1 
ATOM   3874 C  CA  . VAL A 1 531 ? 126.639 118.376 164.339 1.00 56.30  ? 531 VAL A CA  1 
ATOM   3875 C  C   . VAL A 1 531 ? 126.763 116.980 163.745 1.00 56.30  ? 531 VAL A C   1 
ATOM   3876 O  O   . VAL A 1 531 ? 127.771 116.651 163.110 1.00 56.30  ? 531 VAL A O   1 
ATOM   3877 C  CB  . VAL A 1 531 ? 127.041 118.415 165.826 1.00 56.30  ? 531 VAL A CB  1 
ATOM   3878 C  CG1 . VAL A 1 531 ? 128.157 117.427 166.125 1.00 56.30  ? 531 VAL A CG1 1 
ATOM   3879 C  CG2 . VAL A 1 531 ? 127.499 119.809 166.194 1.00 56.30  ? 531 VAL A CG2 1 
ATOM   3880 N  N   . TYR A 1 532 ? 125.737 116.143 163.925 1.00 55.64  ? 532 TYR A N   1 
ATOM   3881 C  CA  . TYR A 1 532 ? 125.762 114.797 163.359 1.00 55.64  ? 532 TYR A CA  1 
ATOM   3882 C  C   . TYR A 1 532 ? 125.827 114.841 161.836 1.00 55.64  ? 532 TYR A C   1 
ATOM   3883 O  O   . TYR A 1 532 ? 126.613 114.115 161.215 1.00 55.64  ? 532 TYR A O   1 
ATOM   3884 C  CB  . TYR A 1 532 ? 124.532 114.011 163.817 1.00 55.64  ? 532 TYR A CB  1 
ATOM   3885 C  CG  . TYR A 1 532 ? 124.405 113.850 165.316 1.00 55.64  ? 532 TYR A CG  1 
ATOM   3886 C  CD1 . TYR A 1 532 ? 123.774 114.818 166.089 1.00 55.64  ? 532 TYR A CD1 1 
ATOM   3887 C  CD2 . TYR A 1 532 ? 124.906 112.725 165.957 1.00 55.64  ? 532 TYR A CD2 1 
ATOM   3888 C  CE1 . TYR A 1 532 ? 123.652 114.672 167.457 1.00 55.64  ? 532 TYR A CE1 1 
ATOM   3889 C  CE2 . TYR A 1 532 ? 124.788 112.571 167.325 1.00 55.64  ? 532 TYR A CE2 1 
ATOM   3890 C  CZ  . TYR A 1 532 ? 124.161 113.547 168.070 1.00 55.64  ? 532 TYR A CZ  1 
ATOM   3891 O  OH  . TYR A 1 532 ? 124.043 113.396 169.432 1.00 55.64  ? 532 TYR A OH  1 
ATOM   3892 N  N   . ALA A 1 533 ? 125.015 115.704 161.219 1.00 56.72  ? 533 ALA A N   1 
ATOM   3893 C  CA  . ALA A 1 533 ? 124.996 115.804 159.762 1.00 56.72  ? 533 ALA A CA  1 
ATOM   3894 C  C   . ALA A 1 533 ? 126.314 116.344 159.221 1.00 56.72  ? 533 ALA A C   1 
ATOM   3895 O  O   . ALA A 1 533 ? 126.833 115.834 158.220 1.00 56.72  ? 533 ALA A O   1 
ATOM   3896 C  CB  . ALA A 1 533 ? 123.831 116.684 159.312 1.00 56.72  ? 533 ALA A CB  1 
ATOM   3897 N  N   . SER A 1 534 ? 126.870 117.372 159.867 1.00 54.20  ? 534 SER A N   1 
ATOM   3898 C  CA  . SER A 1 534 ? 128.145 117.924 159.419 1.00 54.20  ? 534 SER A CA  1 
ATOM   3899 C  C   . SER A 1 534 ? 129.279 116.925 159.613 1.00 54.20  ? 534 SER A C   1 
ATOM   3900 O  O   . SER A 1 534 ? 130.181 116.834 158.775 1.00 54.20  ? 534 SER A O   1 
ATOM   3901 C  CB  . SER A 1 534 ? 128.444 119.228 160.158 1.00 54.20  ? 534 SER A CB  1 
ATOM   3902 O  OG  . SER A 1 534 ? 128.255 119.079 161.552 1.00 54.20  ? 534 SER A OG  1 
ATOM   3903 N  N   . ILE A 1 535 ? 129.241 116.160 160.706 1.00 53.44  ? 535 ILE A N   1 
ATOM   3904 C  CA  . ILE A 1 535 ? 130.251 115.133 160.948 1.00 53.44  ? 535 ILE A CA  1 
ATOM   3905 C  C   . ILE A 1 535 ? 130.170 114.048 159.883 1.00 53.44  ? 535 ILE A C   1 
ATOM   3906 O  O   . ILE A 1 535 ? 131.195 113.602 159.349 1.00 53.44  ? 535 ILE A O   1 
ATOM   3907 C  CB  . ILE A 1 535 ? 130.087 114.560 162.369 1.00 53.44  ? 535 ILE A CB  1 
ATOM   3908 C  CG1 . ILE A 1 535 ? 130.803 115.454 163.384 1.00 53.44  ? 535 ILE A CG1 1 
ATOM   3909 C  CG2 . ILE A 1 535 ? 130.583 113.116 162.455 1.00 53.44  ? 535 ILE A CG2 1 
ATOM   3910 C  CD1 . ILE A 1 535 ? 132.281 115.178 163.515 1.00 53.44  ? 535 ILE A CD1 1 
ATOM   3911 N  N   . GLU A 1 536 ? 128.951 113.618 159.544 1.00 60.56  ? 536 GLU A N   1 
ATOM   3912 C  CA  . GLU A 1 536 ? 128.787 112.593 158.519 1.00 60.56  ? 536 GLU A CA  1 
ATOM   3913 C  C   . GLU A 1 536 ? 129.219 113.100 157.148 1.00 60.56  ? 536 GLU A C   1 
ATOM   3914 O  O   . GLU A 1 536 ? 129.837 112.360 156.375 1.00 60.56  ? 536 GLU A O   1 
ATOM   3915 C  CB  . GLU A 1 536 ? 127.336 112.112 158.484 1.00 60.56  ? 536 GLU A CB  1 
ATOM   3916 C  CG  . GLU A 1 536 ? 126.947 111.237 159.666 1.00 60.56  ? 536 GLU A CG  1 
ATOM   3917 C  CD  . GLU A 1 536 ? 127.625 109.882 159.642 1.00 60.56  ? 536 GLU A CD  1 
ATOM   3918 O  OE1 . GLU A 1 536 ? 127.949 109.395 158.538 1.00 60.56  ? 536 GLU A OE1 1 
ATOM   3919 O  OE2 . GLU A 1 536 ? 127.835 109.302 160.728 1.00 60.56  ? 536 GLU A OE2 1 
ATOM   3920 N  N   . GLU A 1 537 ? 128.913 114.361 156.829 1.00 55.45  ? 537 GLU A N   1 
ATOM   3921 C  CA  . GLU A 1 537 ? 129.311 114.901 155.533 1.00 55.45  ? 537 GLU A CA  1 
ATOM   3922 C  C   . GLU A 1 537 ? 130.810 115.180 155.472 1.00 55.45  ? 537 GLU A C   1 
ATOM   3923 O  O   . GLU A 1 537 ? 131.392 115.178 154.382 1.00 55.45  ? 537 GLU A O   1 
ATOM   3924 C  CB  . GLU A 1 537 ? 128.499 116.159 155.212 1.00 55.45  ? 537 GLU A CB  1 
ATOM   3925 C  CG  . GLU A 1 537 ? 129.066 117.465 155.748 1.00 55.45  ? 537 GLU A CG  1 
ATOM   3926 C  CD  . GLU A 1 537 ? 128.192 118.657 155.408 1.00 55.45  ? 537 GLU A CD  1 
ATOM   3927 O  OE1 . GLU A 1 537 ? 127.184 118.471 154.694 1.00 55.45  ? 537 GLU A OE1 1 
ATOM   3928 O  OE2 . GLU A 1 537 ? 128.508 119.779 155.856 1.00 55.45  ? 537 GLU A OE2 1 
ATOM   3929 N  N   . SER A 1 538 ? 131.450 115.418 156.620 1.00 55.05  ? 538 SER A N   1 
ATOM   3930 C  CA  . SER A 1 538 ? 132.902 115.559 156.638 1.00 55.05  ? 538 SER A CA  1 
ATOM   3931 C  C   . SER A 1 538 ? 133.585 114.207 156.491 1.00 55.05  ? 538 SER A C   1 
ATOM   3932 O  O   . SER A 1 538 ? 134.591 114.087 155.782 1.00 55.05  ? 538 SER A O   1 
ATOM   3933 C  CB  . SER A 1 538 ? 133.346 116.250 157.926 1.00 55.05  ? 538 SER A CB  1 
ATOM   3934 O  OG  . SER A 1 538 ? 133.074 115.439 159.056 1.00 55.05  ? 538 SER A OG  1 
ATOM   3935 N  N   . LYS A 1 539 ? 133.058 113.180 157.162 1.00 59.13  ? 539 LYS A N   1 
ATOM   3936 C  CA  . LYS A 1 539 ? 133.613 111.838 157.025 1.00 59.13  ? 539 LYS A CA  1 
ATOM   3937 C  C   . LYS A 1 539 ? 133.388 111.281 155.626 1.00 59.13  ? 539 LYS A C   1 
ATOM   3938 O  O   . LYS A 1 539 ? 134.219 110.515 155.124 1.00 59.13  ? 539 LYS A O   1 
ATOM   3939 C  CB  . LYS A 1 539 ? 133.004 110.908 158.073 1.00 59.13  ? 539 LYS A CB  1 
ATOM   3940 C  CG  . LYS A 1 539 ? 133.813 109.648 158.331 1.00 59.13  ? 539 LYS A CG  1 
ATOM   3941 C  CD  . LYS A 1 539 ? 135.259 109.979 158.663 1.00 59.13  ? 539 LYS A CD  1 
ATOM   3942 C  CE  . LYS A 1 539 ? 136.080 108.718 158.867 1.00 59.13  ? 539 LYS A CE  1 
ATOM   3943 N  NZ  . LYS A 1 539 ? 137.530 109.020 159.017 1.00 59.13  ? 539 LYS A NZ  1 
ATOM   3944 N  N   . LYS A 1 540 ? 132.276 111.648 154.985 1.00 58.69  ? 540 LYS A N   1 
ATOM   3945 C  CA  . LYS A 1 540 ? 132.052 111.250 153.601 1.00 58.69  ? 540 LYS A CA  1 
ATOM   3946 C  C   . LYS A 1 540 ? 132.983 111.990 152.650 1.00 58.69  ? 540 LYS A C   1 
ATOM   3947 O  O   . LYS A 1 540 ? 133.282 111.490 151.560 1.00 58.69  ? 540 LYS A O   1 
ATOM   3948 C  CB  . LYS A 1 540 ? 130.593 111.494 153.216 1.00 58.69  ? 540 LYS A CB  1 
ATOM   3949 C  CG  . LYS A 1 540 ? 130.096 110.626 152.074 1.00 58.69  ? 540 LYS A CG  1 
ATOM   3950 C  CD  . LYS A 1 540 ? 128.590 110.748 151.908 1.00 58.69  ? 540 LYS A CD  1 
ATOM   3951 C  CE  . LYS A 1 540 ? 128.061 109.732 150.910 1.00 58.69  ? 540 LYS A CE  1 
ATOM   3952 N  NZ  . LYS A 1 540 ? 128.786 109.802 149.611 1.00 58.69  ? 540 LYS A NZ  1 
ATOM   3953 N  N   . ALA A 1 541 ? 133.452 113.171 153.044 1.00 55.38  ? 541 ALA A N   1 
ATOM   3954 C  CA  . ALA A 1 541 ? 134.352 113.975 152.231 1.00 55.38  ? 541 ALA A CA  1 
ATOM   3955 C  C   . ALA A 1 541 ? 135.817 113.625 152.445 1.00 55.38  ? 541 ALA A C   1 
ATOM   3956 O  O   . ALA A 1 541 ? 136.688 114.304 151.892 1.00 55.38  ? 541 ALA A O   1 
ATOM   3957 C  CB  . ALA A 1 541 ? 134.138 115.463 152.520 1.00 55.38  ? 541 ALA A CB  1 
ATOM   3958 N  N   . GLY A 1 542 ? 136.114 112.607 153.247 1.00 58.40  ? 542 GLY A N   1 
ATOM   3959 C  CA  . GLY A 1 542 ? 137.486 112.259 153.542 1.00 58.40  ? 542 GLY A CA  1 
ATOM   3960 C  C   . GLY A 1 542 ? 138.153 113.146 154.567 1.00 58.40  ? 542 GLY A C   1 
ATOM   3961 O  O   . GLY A 1 542 ? 139.346 112.959 154.840 1.00 58.40  ? 542 GLY A O   1 
ATOM   3962 N  N   . ILE A 1 543 ? 137.427 114.103 155.140 1.00 52.64  ? 543 ILE A N   1 
ATOM   3963 C  CA  . ILE A 1 543 ? 137.969 115.004 156.153 1.00 52.64  ? 543 ILE A CA  1 
ATOM   3964 C  C   . ILE A 1 543 ? 137.887 114.275 157.491 1.00 52.64  ? 543 ILE A C   1 
ATOM   3965 O  O   . ILE A 1 543 ? 136.857 114.309 158.166 1.00 52.64  ? 543 ILE A O   1 
ATOM   3966 C  CB  . ILE A 1 543 ? 137.221 116.337 156.190 1.00 52.64  ? 543 ILE A CB  1 
ATOM   3967 C  CG1 . ILE A 1 543 ? 137.210 116.978 154.801 1.00 52.64  ? 543 ILE A CG1 1 
ATOM   3968 C  CG2 . ILE A 1 543 ? 137.849 117.275 157.207 1.00 52.64  ? 543 ILE A CG2 1 
ATOM   3969 C  CD1 . ILE A 1 543 ? 136.345 118.212 154.707 1.00 52.64  ? 543 ILE A CD1 1 
ATOM   3970 N  N   . ARG A 1 544 ? 138.965 113.593 157.866 1.00 55.60  ? 544 ARG A N   1 
ATOM   3971 C  CA  . ARG A 1 544 ? 139.022 112.951 159.171 1.00 55.60  ? 544 ARG A CA  1 
ATOM   3972 C  C   . ARG A 1 544 ? 139.032 114.018 160.257 1.00 55.60  ? 544 ARG A C   1 
ATOM   3973 O  O   . ARG A 1 544 ? 139.846 114.944 160.224 1.00 55.60  ? 544 ARG A O   1 
ATOM   3974 C  CB  . ARG A 1 544 ? 140.264 112.067 159.276 1.00 55.60  ? 544 ARG A CB  1 
ATOM   3975 C  CG  . ARG A 1 544 ? 140.661 111.691 160.699 1.00 55.60  ? 544 ARG A CG  1 
ATOM   3976 C  CD  . ARG A 1 544 ? 139.609 110.815 161.367 1.00 55.60  ? 544 ARG A CD  1 
ATOM   3977 N  NE  . ARG A 1 544 ? 139.799 109.403 161.060 1.00 55.60  ? 544 ARG A NE  1 
ATOM   3978 C  CZ  . ARG A 1 544 ? 140.600 108.591 161.737 1.00 55.60  ? 544 ARG A CZ  1 
ATOM   3979 N  NH1 . ARG A 1 544 ? 141.306 109.020 162.770 1.00 55.60  ? 544 ARG A NH1 1 
ATOM   3980 N  NH2 . ARG A 1 544 ? 140.695 107.317 161.368 1.00 55.60  ? 544 ARG A NH2 1 
ATOM   3981 N  N   . THR A 1 545 ? 138.123 113.899 161.213 1.00 50.38  ? 545 THR A N   1 
ATOM   3982 C  CA  . THR A 1 545 ? 137.995 114.884 162.274 1.00 50.38  ? 545 THR A CA  1 
ATOM   3983 C  C   . THR A 1 545 ? 138.651 114.376 163.553 1.00 50.38  ? 545 THR A C   1 
ATOM   3984 O  O   . THR A 1 545 ? 138.708 113.168 163.803 1.00 50.38  ? 545 THR A O   1 
ATOM   3985 C  CB  . THR A 1 545 ? 136.523 115.243 162.504 1.00 50.38  ? 545 THR A CB  1 
ATOM   3986 O  OG1 . THR A 1 545 ? 136.428 116.442 163.284 1.00 50.38  ? 545 THR A OG1 1 
ATOM   3987 C  CG2 . THR A 1 545 ? 135.768 114.111 163.172 1.00 50.38  ? 545 THR A CG2 1 
ATOM   3988 N  N   . VAL A 1 546 ? 139.193 115.308 164.331 1.00 48.14  ? 546 VAL A N   1 
ATOM   3989 C  CA  . VAL A 1 546 ? 139.925 115.009 165.555 1.00 48.14  ? 546 VAL A CA  1 
ATOM   3990 C  C   . VAL A 1 546 ? 139.409 115.938 166.645 1.00 48.14  ? 546 VAL A C   1 
ATOM   3991 O  O   . VAL A 1 546 ? 139.253 117.142 166.413 1.00 48.14  ? 546 VAL A O   1 
ATOM   3992 C  CB  . VAL A 1 546 ? 141.446 115.169 165.354 1.00 48.14  ? 546 VAL A CB  1 
ATOM   3993 C  CG1 . VAL A 1 546 ? 142.148 115.520 166.655 1.00 48.14  ? 546 VAL A CG1 1 
ATOM   3994 C  CG2 . VAL A 1 546 ? 142.036 113.902 164.755 1.00 48.14  ? 546 VAL A CG2 1 
ATOM   3995 N  N   . MET A 1 547 ? 139.127 115.383 167.821 1.00 53.58  ? 547 MET A N   1 
ATOM   3996 C  CA  . MET A 1 547 ? 138.533 116.139 168.912 1.00 53.58  ? 547 MET A CA  1 
ATOM   3997 C  C   . MET A 1 547 ? 139.372 115.992 170.180 1.00 53.58  ? 547 MET A C   1 
ATOM   3998 O  O   . MET A 1 547 ? 139.690 114.876 170.605 1.00 53.58  ? 547 MET A O   1 
ATOM   3999 C  CB  . MET A 1 547 ? 137.066 115.699 169.105 1.00 53.58  ? 547 MET A CB  1 
ATOM   4000 C  CG  . MET A 1 547 ? 136.865 114.276 169.602 1.00 53.58  ? 547 MET A CG  1 
ATOM   4001 S  SD  . MET A 1 547 ? 135.152 113.888 169.966 1.00 53.58  ? 547 MET A SD  1 
ATOM   4002 C  CE  . MET A 1 547 ? 134.986 114.694 171.549 1.00 53.58  ? 547 MET A CE  1 
ATOM   4003 N  N   . ILE A 1 548 ? 139.766 117.132 170.759 1.00 54.00  ? 548 ILE A N   1 
ATOM   4004 C  CA  . ILE A 1 548 ? 140.573 117.162 171.976 1.00 54.00  ? 548 ILE A CA  1 
ATOM   4005 C  C   . ILE A 1 548 ? 139.662 117.519 173.138 1.00 54.00  ? 548 ILE A C   1 
ATOM   4006 O  O   . ILE A 1 548 ? 138.693 118.272 172.986 1.00 54.00  ? 548 ILE A O   1 
ATOM   4007 C  CB  . ILE A 1 548 ? 141.752 118.160 171.924 1.00 54.00  ? 548 ILE A CB  1 
ATOM   4008 C  CG1 . ILE A 1 548 ? 141.342 119.470 171.257 1.00 54.00  ? 548 ILE A CG1 1 
ATOM   4009 C  CG2 . ILE A 1 548 ? 142.930 117.561 171.191 1.00 54.00  ? 548 ILE A CG2 1 
ATOM   4010 C  CD1 . ILE A 1 548 ? 142.486 120.440 171.042 1.00 54.00  ? 548 ILE A CD1 1 
ATOM   4011 N  N   . THR A 1 549 ? 139.975 116.972 174.309 1.00 62.53  ? 549 THR A N   1 
ATOM   4012 C  CA  . THR A 1 549 ? 139.181 117.241 175.499 1.00 62.53  ? 549 THR A CA  1 
ATOM   4013 C  C   . THR A 1 549 ? 140.102 117.151 176.711 1.00 62.53  ? 549 THR A C   1 
ATOM   4014 O  O   . THR A 1 549 ? 141.187 116.571 176.641 1.00 62.53  ? 549 THR A O   1 
ATOM   4015 C  CB  . THR A 1 549 ? 138.006 116.260 175.623 1.00 62.53  ? 549 THR A CB  1 
ATOM   4016 O  OG1 . THR A 1 549 ? 137.393 116.069 174.342 1.00 62.53  ? 549 THR A OG1 1 
ATOM   4017 C  CG2 . THR A 1 549 ? 136.949 116.837 176.519 1.00 62.53  ? 549 THR A CG2 1 
ATOM   4018 N  N   . GLY A 1 550 ? 139.670 117.759 177.817 1.00 71.85  ? 550 GLY A N   1 
ATOM   4019 C  CA  . GLY A 1 550 ? 140.410 117.721 179.061 1.00 71.85  ? 550 GLY A CA  1 
ATOM   4020 C  C   . GLY A 1 550 ? 139.816 116.914 180.196 1.00 71.85  ? 550 GLY A C   1 
ATOM   4021 O  O   . GLY A 1 550 ? 140.385 116.915 181.291 1.00 71.85  ? 550 GLY A O   1 
ATOM   4022 N  N   . ASP A 1 551 ? 138.690 116.229 179.988 1.00 75.88  ? 551 ASP A N   1 
ATOM   4023 C  CA  . ASP A 1 551 ? 138.066 115.475 181.068 1.00 75.88  ? 551 ASP A CA  1 
ATOM   4024 C  C   . ASP A 1 551 ? 138.569 114.031 181.047 1.00 75.88  ? 551 ASP A C   1 
ATOM   4025 O  O   . ASP A 1 551 ? 139.577 113.706 180.413 1.00 75.88  ? 551 ASP A O   1 
ATOM   4026 C  CB  . ASP A 1 551 ? 136.542 115.519 180.975 1.00 75.88  ? 551 ASP A CB  1 
ATOM   4027 C  CG  . ASP A 1 551 ? 136.042 115.486 179.554 1.00 75.88  ? 551 ASP A CG  1 
ATOM   4028 O  OD1 . ASP A 1 551 ? 136.537 114.641 178.778 1.00 75.88  ? 551 ASP A OD1 1 
ATOM   4029 O  OD2 . ASP A 1 551 ? 135.155 116.296 179.215 1.00 75.88  ? 551 ASP A OD2 1 
ATOM   4030 N  N   . HIS A 1 552 ? 137.864 113.155 181.760 1.00 76.57  ? 552 HIS A N   1 
ATOM   4031 C  CA  . HIS A 1 552 ? 138.250 111.756 181.878 1.00 76.57  ? 552 HIS A CA  1 
ATOM   4032 C  C   . HIS A 1 552 ? 138.126 111.079 180.510 1.00 76.57  ? 552 HIS A C   1 
ATOM   4033 O  O   . HIS A 1 552 ? 137.328 111.487 179.662 1.00 76.57  ? 552 HIS A O   1 
ATOM   4034 C  CB  . HIS A 1 552 ? 137.367 111.080 182.934 1.00 76.57  ? 552 HIS A CB  1 
ATOM   4035 C  CG  . HIS A 1 552 ? 137.548 109.597 183.055 1.00 76.57  ? 552 HIS A CG  1 
ATOM   4036 N  ND1 . HIS A 1 552 ? 138.773 108.979 182.926 1.00 76.57  ? 552 HIS A ND1 1 
ATOM   4037 C  CD2 . HIS A 1 552 ? 136.658 108.612 183.321 1.00 76.57  ? 552 HIS A CD2 1 
ATOM   4038 C  CE1 . HIS A 1 552 ? 138.629 107.677 183.092 1.00 76.57  ? 552 HIS A CE1 1 
ATOM   4039 N  NE2 . HIS A 1 552 ? 137.356 107.428 183.337 1.00 76.57  ? 552 HIS A NE2 1 
ATOM   4040 N  N   . LYS A 1 553 ? 138.939 110.039 180.300 1.00 70.21  ? 553 LYS A N   1 
ATOM   4041 C  CA  . LYS A 1 553 ? 139.193 109.516 178.959 1.00 70.21  ? 553 LYS A CA  1 
ATOM   4042 C  C   . LYS A 1 553 ? 137.952 108.872 178.346 1.00 70.21  ? 553 LYS A C   1 
ATOM   4043 O  O   . LYS A 1 553 ? 137.475 109.303 177.289 1.00 70.21  ? 553 LYS A O   1 
ATOM   4044 C  CB  . LYS A 1 553 ? 140.351 108.514 179.014 1.00 70.21  ? 553 LYS A CB  1 
ATOM   4045 C  CG  . LYS A 1 553 ? 140.639 107.797 177.705 1.00 70.21  ? 553 LYS A CG  1 
ATOM   4046 C  CD  . LYS A 1 553 ? 140.752 108.791 176.566 1.00 70.21  ? 553 LYS A CD  1 
ATOM   4047 C  CE  . LYS A 1 553 ? 141.529 108.251 175.405 1.00 70.21  ? 553 LYS A CE  1 
ATOM   4048 N  NZ  . LYS A 1 553 ? 141.832 109.350 174.447 1.00 70.21  ? 553 LYS A NZ  1 
ATOM   4049 N  N   . THR A 1 554 ? 137.434 107.815 178.975 1.00 74.62  ? 554 THR A N   1 
ATOM   4050 C  CA  . THR A 1 554 ? 136.348 107.056 178.362 1.00 74.62  ? 554 THR A CA  1 
ATOM   4051 C  C   . THR A 1 554 ? 135.060 107.861 178.255 1.00 74.62  ? 554 THR A C   1 
ATOM   4052 O  O   . THR A 1 554 ? 134.218 107.540 177.410 1.00 74.62  ? 554 THR A O   1 
ATOM   4053 C  CB  . THR A 1 554 ? 136.105 105.762 179.136 1.00 74.62  ? 554 THR A CB  1 
ATOM   4054 O  OG1 . THR A 1 554 ? 135.775 106.068 180.497 1.00 74.62  ? 554 THR A OG1 1 
ATOM   4055 C  CG2 . THR A 1 554 ? 137.333 104.882 179.089 1.00 74.62  ? 554 THR A CG2 1 
ATOM   4056 N  N   . THR A 1 555 ? 134.901 108.911 179.066 1.00 74.14  ? 555 THR A N   1 
ATOM   4057 C  CA  . THR A 1 555 ? 133.814 109.858 178.844 1.00 74.14  ? 555 THR A CA  1 
ATOM   4058 C  C   . THR A 1 555 ? 133.935 110.501 177.468 1.00 74.14  ? 555 THR A C   1 
ATOM   4059 O  O   . THR A 1 555 ? 132.967 110.543 176.700 1.00 74.14  ? 555 THR A O   1 
ATOM   4060 C  CB  . THR A 1 555 ? 133.820 110.934 179.930 1.00 74.14  ? 555 THR A CB  1 
ATOM   4061 O  OG1 . THR A 1 555 ? 134.851 111.889 179.647 1.00 74.14  ? 555 THR A OG1 1 
ATOM   4062 C  CG2 . THR A 1 555 ? 134.084 110.318 181.291 1.00 74.14  ? 555 THR A CG2 1 
ATOM   4063 N  N   . ALA A 1 556 ? 135.136 110.978 177.129 1.00 71.99  ? 556 ALA A N   1 
ATOM   4064 C  CA  . ALA A 1 556 ? 135.365 111.557 175.810 1.00 71.99  ? 556 ALA A CA  1 
ATOM   4065 C  C   . ALA A 1 556 ? 135.274 110.506 174.712 1.00 71.99  ? 556 ALA A C   1 
ATOM   4066 O  O   . ALA A 1 556 ? 134.854 110.820 173.594 1.00 71.99  ? 556 ALA A O   1 
ATOM   4067 C  CB  . ALA A 1 556 ? 136.724 112.254 175.770 1.00 71.99  ? 556 ALA A CB  1 
ATOM   4068 N  N   . GLN A 1 557 ? 135.654 109.261 175.010 1.00 68.73  ? 557 GLN A N   1 
ATOM   4069 C  CA  . GLN A 1 557 ? 135.503 108.186 174.031 1.00 68.73  ? 557 GLN A CA  1 
ATOM   4070 C  C   . GLN A 1 557 ? 134.033 107.935 173.706 1.00 68.73  ? 557 GLN A C   1 
ATOM   4071 O  O   . GLN A 1 557 ? 133.662 107.788 172.535 1.00 68.73  ? 557 GLN A O   1 
ATOM   4072 C  CB  . GLN A 1 557 ? 136.162 106.909 174.551 1.00 68.73  ? 557 GLN A CB  1 
ATOM   4073 C  CG  . GLN A 1 557 ? 135.913 105.684 173.687 1.00 68.73  ? 557 GLN A CG  1 
ATOM   4074 C  CD  . GLN A 1 557 ? 136.419 104.406 174.326 1.00 68.73  ? 557 GLN A CD  1 
ATOM   4075 O  OE1 . GLN A 1 557 ? 136.073 103.305 173.898 1.00 68.73  ? 557 GLN A OE1 1 
ATOM   4076 N  NE2 . GLN A 1 557 ? 137.245 104.546 175.356 1.00 68.73  ? 557 GLN A NE2 1 
ATOM   4077 N  N   . ALA A 1 558 ? 133.180 107.896 174.731 1.00 72.90  ? 558 ALA A N   1 
ATOM   4078 C  CA  . ALA A 1 558 ? 131.751 107.712 174.496 1.00 72.90  ? 558 ALA A CA  1 
ATOM   4079 C  C   . ALA A 1 558 ? 131.139 108.933 173.822 1.00 72.90  ? 558 ALA A C   1 
ATOM   4080 O  O   . ALA A 1 558 ? 130.213 108.801 173.014 1.00 72.90  ? 558 ALA A O   1 
ATOM   4081 C  CB  . ALA A 1 558 ? 131.035 107.407 175.807 1.00 72.90  ? 558 ALA A CB  1 
ATOM   4082 N  N   . ILE A 1 559 ? 131.640 110.130 174.145 1.00 67.43  ? 559 ILE A N   1 
ATOM   4083 C  CA  . ILE A 1 559 ? 131.202 111.333 173.441 1.00 67.43  ? 559 ILE A CA  1 
ATOM   4084 C  C   . ILE A 1 559 ? 131.531 111.227 171.959 1.00 67.43  ? 559 ILE A C   1 
ATOM   4085 O  O   . ILE A 1 559 ? 130.698 111.535 171.100 1.00 67.43  ? 559 ILE A O   1 
ATOM   4086 C  CB  . ILE A 1 559 ? 131.833 112.590 174.070 1.00 67.43  ? 559 ILE A CB  1 
ATOM   4087 C  CG1 . ILE A 1 559 ? 131.185 112.909 175.417 1.00 67.43  ? 559 ILE A CG1 1 
ATOM   4088 C  CG2 . ILE A 1 559 ? 131.705 113.779 173.134 1.00 67.43  ? 559 ILE A CG2 1 
ATOM   4089 C  CD1 . ILE A 1 559 ? 132.088 113.671 176.363 1.00 67.43  ? 559 ILE A CD1 1 
ATOM   4090 N  N   . GLY A 1 560 ? 132.743 110.775 171.638 1.00 69.58  ? 560 GLY A N   1 
ATOM   4091 C  CA  . GLY A 1 560 ? 133.118 110.604 170.245 1.00 69.58  ? 560 GLY A CA  1 
ATOM   4092 C  C   . GLY A 1 560 ? 132.312 109.526 169.544 1.00 69.58  ? 560 GLY A C   1 
ATOM   4093 O  O   . GLY A 1 560 ? 132.024 109.634 168.349 1.00 69.58  ? 560 GLY A O   1 
ATOM   4094 N  N   . ARG A 1 561 ? 131.956 108.465 170.272 1.00 72.41  ? 561 ARG A N   1 
ATOM   4095 C  CA  . ARG A 1 561 ? 131.062 107.453 169.714 1.00 72.41  ? 561 ARG A CA  1 
ATOM   4096 C  C   . ARG A 1 561 ? 129.688 108.040 169.415 1.00 72.41  ? 561 ARG A C   1 
ATOM   4097 O  O   . ARG A 1 561 ? 129.070 107.710 168.396 1.00 72.41  ? 561 ARG A O   1 
ATOM   4098 C  CB  . ARG A 1 561 ? 130.941 106.269 170.674 1.00 72.41  ? 561 ARG A CB  1 
ATOM   4099 C  CG  . ARG A 1 561 ? 130.440 104.990 170.020 1.00 72.41  ? 561 ARG A CG  1 
ATOM   4100 C  CD  . ARG A 1 561 ? 130.938 103.752 170.750 1.00 72.41  ? 561 ARG A CD  1 
ATOM   4101 N  NE  . ARG A 1 561 ? 132.372 103.548 170.585 1.00 72.41  ? 561 ARG A NE  1 
ATOM   4102 C  CZ  . ARG A 1 561 ? 133.275 103.773 171.530 1.00 72.41  ? 561 ARG A CZ  1 
ATOM   4103 N  NH1 . ARG A 1 561 ? 132.926 104.215 172.728 1.00 72.41  ? 561 ARG A NH1 1 
ATOM   4104 N  NH2 . ARG A 1 561 ? 134.559 103.547 171.268 1.00 72.41  ? 561 ARG A NH2 1 
ATOM   4105 N  N   . ASP A 1 562 ? 129.189 108.900 170.307 1.00 69.65  ? 562 ASP A N   1 
ATOM   4106 C  CA  . ASP A 1 562 ? 127.906 109.562 170.088 1.00 69.65  ? 562 ASP A CA  1 
ATOM   4107 C  C   . ASP A 1 562 ? 127.985 110.482 168.871 1.00 69.65  ? 562 ASP A C   1 
ATOM   4108 O  O   . ASP A 1 562 ? 127.079 110.485 168.029 1.00 69.65  ? 562 ASP A O   1 
ATOM   4109 C  CB  . ASP A 1 562 ? 127.524 110.325 171.369 1.00 69.65  ? 562 ASP A CB  1 
ATOM   4110 C  CG  . ASP A 1 562 ? 126.320 111.276 171.215 1.00 69.65  ? 562 ASP A CG  1 
ATOM   4111 O  OD1 . ASP A 1 562 ? 125.589 111.269 170.203 1.00 69.65  ? 562 ASP A OD1 1 
ATOM   4112 O  OD2 . ASP A 1 562 ? 126.104 112.065 172.159 1.00 69.65  ? 562 ASP A OD2 1 
ATOM   4113 N  N   . ILE A 1 563 ? 129.076 111.243 168.753 1.00 62.63  ? 563 ILE A N   1 
ATOM   4114 C  CA  . ILE A 1 563 ? 129.218 112.217 167.674 1.00 62.63  ? 563 ILE A CA  1 
ATOM   4115 C  C   . ILE A 1 563 ? 129.263 111.519 166.320 1.00 62.63  ? 563 ILE A C   1 
ATOM   4116 O  O   . ILE A 1 563 ? 128.585 111.926 165.369 1.00 62.63  ? 563 ILE A O   1 
ATOM   4117 C  CB  . ILE A 1 563 ? 130.469 113.085 167.908 1.00 62.63  ? 563 ILE A CB  1 
ATOM   4118 C  CG1 . ILE A 1 563 ? 130.264 114.011 169.109 1.00 62.63  ? 563 ILE A CG1 1 
ATOM   4119 C  CG2 . ILE A 1 563 ? 130.816 113.882 166.668 1.00 62.63  ? 563 ILE A CG2 1 
ATOM   4120 C  CD1 . ILE A 1 563 ? 129.337 115.171 168.844 1.00 62.63  ? 563 ILE A CD1 1 
ATOM   4121 N  N   . GLY A 1 564 ? 130.045 110.449 166.214 1.00 65.54  ? 564 GLY A N   1 
ATOM   4122 C  CA  . GLY A 1 564 ? 130.085 109.682 164.986 1.00 65.54  ? 564 GLY A CA  1 
ATOM   4123 C  C   . GLY A 1 564 ? 131.461 109.544 164.370 1.00 65.54  ? 564 GLY A C   1 
ATOM   4124 O  O   . GLY A 1 564 ? 131.587 109.099 163.225 1.00 65.54  ? 564 GLY A O   1 
ATOM   4125 N  N   . LEU A 1 565 ? 132.502 109.922 165.107 1.00 62.15  ? 565 LEU A N   1 
ATOM   4126 C  CA  . LEU A 1 565 ? 133.870 109.773 164.632 1.00 62.15  ? 565 LEU A CA  1 
ATOM   4127 C  C   . LEU A 1 565 ? 134.519 108.490 165.132 1.00 62.15  ? 565 LEU A C   1 
ATOM   4128 O  O   . LEU A 1 565 ? 135.675 108.219 164.793 1.00 62.15  ? 565 LEU A O   1 
ATOM   4129 C  CB  . LEU A 1 565 ? 134.704 110.997 165.039 1.00 62.15  ? 565 LEU A CB  1 
ATOM   4130 C  CG  . LEU A 1 565 ? 134.607 111.568 166.462 1.00 62.15  ? 565 LEU A CG  1 
ATOM   4131 C  CD1 . LEU A 1 565 ? 135.356 110.716 167.482 1.00 62.15  ? 565 LEU A CD1 1 
ATOM   4132 C  CD2 . LEU A 1 565 ? 135.065 113.013 166.527 1.00 62.15  ? 565 LEU A CD2 1 
ATOM   4133 N  N   . MET A 1 566 ? 133.802 107.700 165.927 1.00 79.80  ? 566 MET A N   1 
ATOM   4134 C  CA  . MET A 1 566 ? 134.279 106.423 166.442 1.00 79.80  ? 566 MET A CA  1 
ATOM   4135 C  C   . MET A 1 566 ? 133.467 105.296 165.824 1.00 79.80  ? 566 MET A C   1 
ATOM   4136 O  O   . MET A 1 566 ? 132.237 105.271 165.949 1.00 79.80  ? 566 MET A O   1 
ATOM   4137 C  CB  . MET A 1 566 ? 134.179 106.368 167.967 1.00 79.80  ? 566 MET A CB  1 
ATOM   4138 C  CG  . MET A 1 566 ? 135.312 107.045 168.709 1.00 79.80  ? 566 MET A CG  1 
ATOM   4139 S  SD  . MET A 1 566 ? 136.883 106.358 168.162 1.00 79.80  ? 566 MET A SD  1 
ATOM   4140 C  CE  . MET A 1 566 ? 137.892 106.550 169.624 1.00 79.80  ? 566 MET A CE  1 
ATOM   4141 N  N   . ASP A 1 567 ? 134.158 104.365 165.170 1.00 92.01  ? 567 ASP A N   1 
ATOM   4142 C  CA  . ASP A 1 567 ? 133.533 103.155 164.651 1.00 92.01  ? 567 ASP A CA  1 
ATOM   4143 C  C   . ASP A 1 567 ? 134.618 102.122 164.395 1.00 92.01  ? 567 ASP A C   1 
ATOM   4144 O  O   . ASP A 1 567 ? 135.636 102.435 163.769 1.00 92.01  ? 567 ASP A O   1 
ATOM   4145 C  CB  . ASP A 1 567 ? 132.739 103.434 163.366 1.00 92.01  ? 567 ASP A CB  1 
ATOM   4146 C  CG  . ASP A 1 567 ? 133.607 103.965 162.244 1.00 92.01  ? 567 ASP A CG  1 
ATOM   4147 O  OD1 . ASP A 1 567 ? 134.812 104.191 162.475 1.00 92.01  ? 567 ASP A OD1 1 
ATOM   4148 O  OD2 . ASP A 1 567 ? 133.082 104.158 161.127 1.00 92.01  ? 567 ASP A OD2 1 
ATOM   4149 N  N   . ALA A 1 568 ? 134.400 100.906 164.903 1.00 94.80  ? 568 ALA A N   1 
ATOM   4150 C  CA  . ALA A 1 568 ? 135.250 99.742  164.661 1.00 94.80  ? 568 ALA A CA  1 
ATOM   4151 C  C   . ALA A 1 568 ? 136.693 99.941  165.115 1.00 94.80  ? 568 ALA A C   1 
ATOM   4152 O  O   . ALA A 1 568 ? 136.976 99.959  166.317 1.00 94.80  ? 568 ALA A O   1 
ATOM   4153 C  CB  . ALA A 1 568 ? 135.215 99.356  163.178 1.00 94.80  ? 568 ALA A CB  1 
ATOM   4154 N  N   . ASP A 1 569 ? 137.608 100.094 164.157 1.00 91.42  ? 569 ASP A N   1 
ATOM   4155 C  CA  . ASP A 1 569 ? 139.039 100.000 164.421 1.00 91.42  ? 569 ASP A CA  1 
ATOM   4156 C  C   . ASP A 1 569 ? 139.640 101.256 165.039 1.00 91.42  ? 569 ASP A C   1 
ATOM   4157 O  O   . ASP A 1 569 ? 140.824 101.237 165.393 1.00 91.42  ? 569 ASP A O   1 
ATOM   4158 C  CB  . ASP A 1 569 ? 139.785 99.673  163.126 1.00 91.42  ? 569 ASP A CB  1 
ATOM   4159 C  CG  . ASP A 1 569 ? 139.636 100.759 162.079 1.00 91.42  ? 569 ASP A CG  1 
ATOM   4160 O  OD1 . ASP A 1 569 ? 138.531 101.330 161.967 1.00 91.42  ? 569 ASP A OD1 1 
ATOM   4161 O  OD2 . ASP A 1 569 ? 140.623 101.042 161.368 1.00 91.42  ? 569 ASP A OD2 1 
ATOM   4162 N  N   . ASP A 1 570 ? 138.877 102.338 165.169 1.00 86.05  ? 570 ASP A N   1 
ATOM   4163 C  CA  . ASP A 1 570 ? 139.434 103.575 165.696 1.00 86.05  ? 570 ASP A CA  1 
ATOM   4164 C  C   . ASP A 1 570 ? 139.740 103.449 167.186 1.00 86.05  ? 570 ASP A C   1 
ATOM   4165 O  O   . ASP A 1 570 ? 139.063 102.731 167.927 1.00 86.05  ? 570 ASP A O   1 
ATOM   4166 C  CB  . ASP A 1 570 ? 138.478 104.740 165.449 1.00 86.05  ? 570 ASP A CB  1 
ATOM   4167 C  CG  . ASP A 1 570 ? 138.002 104.808 164.013 1.00 86.05  ? 570 ASP A CG  1 
ATOM   4168 O  OD1 . ASP A 1 570 ? 138.526 104.046 163.173 1.00 86.05  ? 570 ASP A OD1 1 
ATOM   4169 O  OD2 . ASP A 1 570 ? 137.110 105.632 163.723 1.00 86.05  ? 570 ASP A OD2 1 
ATOM   4170 N  N   . ILE A 1 571 ? 140.778 104.165 167.619 1.00 75.20  ? 571 ILE A N   1 
ATOM   4171 C  CA  . ILE A 1 571 ? 141.305 104.080 168.974 1.00 75.20  ? 571 ILE A CA  1 
ATOM   4172 C  C   . ILE A 1 571 ? 141.400 105.492 169.545 1.00 75.20  ? 571 ILE A C   1 
ATOM   4173 O  O   . ILE A 1 571 ? 141.198 106.483 168.843 1.00 75.20  ? 571 ILE A O   1 
ATOM   4174 C  CB  . ILE A 1 571 ? 142.677 103.364 169.012 1.00 75.20  ? 571 ILE A CB  1 
ATOM   4175 C  CG1 . ILE A 1 571 ? 142.879 102.620 170.337 1.00 75.20  ? 571 ILE A CG1 1 
ATOM   4176 C  CG2 . ILE A 1 571 ? 143.821 104.336 168.712 1.00 75.20  ? 571 ILE A CG2 1 
ATOM   4177 C  CD1 . ILE A 1 571 ? 144.193 101.875 170.426 1.00 75.20  ? 571 ILE A CD1 1 
ATOM   4178 N  N   . ALA A 1 572 ? 141.682 105.576 170.845 1.00 64.95  ? 572 ALA A N   1 
ATOM   4179 C  CA  . ALA A 1 572 ? 141.848 106.856 171.517 1.00 64.95  ? 572 ALA A CA  1 
ATOM   4180 C  C   . ALA A 1 572 ? 142.886 106.724 172.622 1.00 64.95  ? 572 ALA A C   1 
ATOM   4181 O  O   . ALA A 1 572 ? 142.878 105.748 173.377 1.00 64.95  ? 572 ALA A O   1 
ATOM   4182 C  CB  . ALA A 1 572 ? 140.516 107.352 172.087 1.00 64.95  ? 572 ALA A CB  1 
ATOM   4183 N  N   . LEU A 1 573 ? 143.772 107.717 172.717 1.00 65.20  ? 573 LEU A N   1 
ATOM   4184 C  CA  . LEU A 1 573 ? 144.873 107.722 173.672 1.00 65.20  ? 573 LEU A CA  1 
ATOM   4185 C  C   . LEU A 1 573 ? 144.890 109.047 174.421 1.00 65.20  ? 573 LEU A C   1 
ATOM   4186 O  O   . LEU A 1 573 ? 144.655 110.105 173.829 1.00 65.20  ? 573 LEU A O   1 
ATOM   4187 C  CB  . LEU A 1 573 ? 146.221 107.508 172.972 1.00 65.20  ? 573 LEU A CB  1 
ATOM   4188 C  CG  . LEU A 1 573 ? 146.396 106.233 172.142 1.00 65.20  ? 573 LEU A CG  1 
ATOM   4189 C  CD1 . LEU A 1 573 ? 147.810 106.152 171.587 1.00 65.20  ? 573 LEU A CD1 1 
ATOM   4190 C  CD2 . LEU A 1 573 ? 146.063 104.993 172.956 1.00 65.20  ? 573 LEU A CD2 1 
ATOM   4191 N  N   . THR A 1 574 ? 145.167 108.986 175.722 1.00 64.13  ? 574 THR A N   1 
ATOM   4192 C  CA  . THR A 1 574 ? 145.118 110.179 176.554 1.00 64.13  ? 574 THR A CA  1 
ATOM   4193 C  C   . THR A 1 574 ? 146.329 111.073 176.291 1.00 64.13  ? 574 THR A C   1 
ATOM   4194 O  O   . THR A 1 574 ? 147.251 110.725 175.548 1.00 64.13  ? 574 THR A O   1 
ATOM   4195 C  CB  . THR A 1 574 ? 145.076 109.811 178.037 1.00 64.13  ? 574 THR A CB  1 
ATOM   4196 O  OG1 . THR A 1 574 ? 146.377 109.393 178.464 1.00 64.13  ? 574 THR A OG1 1 
ATOM   4197 C  CG2 . THR A 1 574 ? 144.099 108.680 178.276 1.00 64.13  ? 574 THR A CG2 1 
ATOM   4198 N  N   . GLY A 1 575 ? 146.312 112.249 176.921 1.00 66.63  ? 575 GLY A N   1 
ATOM   4199 C  CA  . GLY A 1 575 ? 147.455 113.142 176.835 1.00 66.63  ? 575 GLY A CA  1 
ATOM   4200 C  C   . GLY A 1 575 ? 148.687 112.586 177.524 1.00 66.63  ? 575 GLY A C   1 
ATOM   4201 O  O   . GLY A 1 575 ? 149.814 112.806 177.071 1.00 66.63  ? 575 GLY A O   1 
ATOM   4202 N  N   . GLN A 1 576 ? 148.489 111.870 178.636 1.00 66.05  ? 576 GLN A N   1 
ATOM   4203 C  CA  . GLN A 1 576 ? 149.613 111.267 179.346 1.00 66.05  ? 576 GLN A CA  1 
ATOM   4204 C  C   . GLN A 1 576 ? 150.316 110.224 178.486 1.00 66.05  ? 576 GLN A C   1 
ATOM   4205 O  O   . GLN A 1 576 ? 151.550 110.150 178.471 1.00 66.05  ? 576 GLN A O   1 
ATOM   4206 C  CB  . GLN A 1 576 ? 149.132 110.647 180.658 1.00 66.05  ? 576 GLN A CB  1 
ATOM   4207 C  CG  . GLN A 1 576 ? 148.800 111.663 181.737 1.00 66.05  ? 576 GLN A CG  1 
ATOM   4208 C  CD  . GLN A 1 576 ? 148.759 111.049 183.121 1.00 66.05  ? 576 GLN A CD  1 
ATOM   4209 O  OE1 . GLN A 1 576 ? 148.763 109.827 183.271 1.00 66.05  ? 576 GLN A OE1 1 
ATOM   4210 N  NE2 . GLN A 1 576 ? 148.721 111.896 184.143 1.00 66.05  ? 576 GLN A NE2 1 
ATOM   4211 N  N   . GLU A 1 577 ? 149.548 109.407 177.764 1.00 66.12  ? 577 GLU A N   1 
ATOM   4212 C  CA  . GLU A 1 577 ? 150.145 108.510 176.784 1.00 66.12  ? 577 GLU A CA  1 
ATOM   4213 C  C   . GLU A 1 577 ? 150.629 109.258 175.550 1.00 66.12  ? 577 GLU A C   1 
ATOM   4214 O  O   . GLU A 1 577 ? 151.498 108.751 174.833 1.00 66.12  ? 577 GLU A O   1 
ATOM   4215 C  CB  . GLU A 1 577 ? 149.146 107.425 176.379 1.00 66.12  ? 577 GLU A CB  1 
ATOM   4216 C  CG  . GLU A 1 577 ? 148.248 106.960 177.511 1.00 66.12  ? 577 GLU A CG  1 
ATOM   4217 C  CD  . GLU A 1 577 ? 147.195 105.972 177.052 1.00 66.12  ? 577 GLU A CD  1 
ATOM   4218 O  OE1 . GLU A 1 577 ? 147.360 105.390 175.960 1.00 66.12  ? 577 GLU A OE1 1 
ATOM   4219 O  OE2 . GLU A 1 577 ? 146.199 105.781 177.782 1.00 66.12  ? 577 GLU A OE2 1 
ATOM   4220 N  N   . LEU A 1 578 ? 150.080 110.445 175.285 1.00 65.99  ? 578 LEU A N   1 
ATOM   4221 C  CA  . LEU A 1 578 ? 150.496 111.220 174.121 1.00 65.99  ? 578 LEU A CA  1 
ATOM   4222 C  C   . LEU A 1 578 ? 151.910 111.762 174.294 1.00 65.99  ? 578 LEU A C   1 
ATOM   4223 O  O   . LEU A 1 578 ? 152.736 111.672 173.378 1.00 65.99  ? 578 LEU A O   1 
ATOM   4224 C  CB  . LEU A 1 578 ? 149.505 112.357 173.875 1.00 65.99  ? 578 LEU A CB  1 
ATOM   4225 C  CG  . LEU A 1 578 ? 149.238 112.785 172.436 1.00 65.99  ? 578 LEU A CG  1 
ATOM   4226 C  CD1 . LEU A 1 578 ? 148.749 111.608 171.614 1.00 65.99  ? 578 LEU A CD1 1 
ATOM   4227 C  CD2 . LEU A 1 578 ? 148.212 113.899 172.432 1.00 65.99  ? 578 LEU A CD2 1 
ATOM   4228 N  N   . ASP A 1 579 ? 152.210 112.331 175.462 1.00 72.72  ? 579 ASP A N   1 
ATOM   4229 C  CA  . ASP A 1 579 ? 153.539 112.887 175.693 1.00 72.72  ? 579 ASP A CA  1 
ATOM   4230 C  C   . ASP A 1 579 ? 154.557 111.844 176.137 1.00 72.72  ? 579 ASP A C   1 
ATOM   4231 O  O   . ASP A 1 579 ? 155.736 112.183 176.291 1.00 72.72  ? 579 ASP A O   1 
ATOM   4232 C  CB  . ASP A 1 579 ? 153.483 114.026 176.722 1.00 72.72  ? 579 ASP A CB  1 
ATOM   4233 C  CG  . ASP A 1 579 ? 152.671 113.674 177.956 1.00 72.72  ? 579 ASP A CG  1 
ATOM   4234 O  OD1 . ASP A 1 579 ? 152.964 112.646 178.602 1.00 72.72  ? 579 ASP A OD1 1 
ATOM   4235 O  OD2 . ASP A 1 579 ? 151.752 114.448 178.295 1.00 72.72  ? 579 ASP A OD2 1 
ATOM   4236 N  N   . ALA A 1 580 ? 154.143 110.597 176.344 1.00 70.90  ? 580 ALA A N   1 
ATOM   4237 C  CA  . ALA A 1 580 ? 155.040 109.514 176.733 1.00 70.90  ? 580 ALA A CA  1 
ATOM   4238 C  C   . ALA A 1 580 ? 155.168 108.473 175.625 1.00 70.90  ? 580 ALA A C   1 
ATOM   4239 O  O   . ALA A 1 580 ? 155.237 107.270 175.886 1.00 70.90  ? 580 ALA A O   1 
ATOM   4240 C  CB  . ALA A 1 580 ? 154.570 108.860 178.029 1.00 70.90  ? 580 ALA A CB  1 
ATOM   4241 N  N   . MET A 1 581 ? 155.203 108.926 174.373 1.00 73.89  ? 581 MET A N   1 
ATOM   4242 C  CA  . MET A 1 581 ? 155.253 108.017 173.236 1.00 73.89  ? 581 MET A CA  1 
ATOM   4243 C  C   . MET A 1 581 ? 155.990 108.723 172.102 1.00 73.89  ? 581 MET A C   1 
ATOM   4244 O  O   . MET A 1 581 ? 155.593 109.825 171.700 1.00 73.89  ? 581 MET A O   1 
ATOM   4245 C  CB  . MET A 1 581 ? 153.830 107.611 172.831 1.00 73.89  ? 581 MET A CB  1 
ATOM   4246 C  CG  . MET A 1 581 ? 153.595 107.245 171.367 1.00 73.89  ? 581 MET A CG  1 
ATOM   4247 S  SD  . MET A 1 581 ? 154.660 105.926 170.747 1.00 73.89  ? 581 MET A SD  1 
ATOM   4248 C  CE  . MET A 1 581 ? 153.699 104.480 171.185 1.00 73.89  ? 581 MET A CE  1 
ATOM   4249 N  N   . PRO A 1 582 ? 157.076 108.149 171.588 1.00 71.57  ? 582 PRO A N   1 
ATOM   4250 C  CA  . PRO A 1 582 ? 157.819 108.801 170.501 1.00 71.57  ? 582 PRO A CA  1 
ATOM   4251 C  C   . PRO A 1 582 ? 157.021 108.850 169.206 1.00 71.57  ? 582 PRO A C   1 
ATOM   4252 O  O   . PRO A 1 582 ? 156.101 108.064 168.970 1.00 71.57  ? 582 PRO A O   1 
ATOM   4253 C  CB  . PRO A 1 582 ? 159.072 107.930 170.347 1.00 71.57  ? 582 PRO A CB  1 
ATOM   4254 C  CG  . PRO A 1 582 ? 158.744 106.639 171.024 1.00 71.57  ? 582 PRO A CG  1 
ATOM   4255 C  CD  . PRO A 1 582 ? 157.791 106.978 172.122 1.00 71.57  ? 582 PRO A CD  1 
ATOM   4256 N  N   . GLU A 1 583 ? 157.396 109.807 168.352 1.00 68.56  ? 583 GLU A N   1 
ATOM   4257 C  CA  . GLU A 1 583 ? 156.636 110.082 167.137 1.00 68.56  ? 583 GLU A CA  1 
ATOM   4258 C  C   . GLU A 1 583 ? 156.709 108.952 166.115 1.00 68.56  ? 583 GLU A C   1 
ATOM   4259 O  O   . GLU A 1 583 ? 155.871 108.911 165.207 1.00 68.56  ? 583 GLU A O   1 
ATOM   4260 C  CB  . GLU A 1 583 ? 157.124 111.385 166.501 1.00 68.56  ? 583 GLU A CB  1 
ATOM   4261 C  CG  . GLU A 1 583 ? 156.037 112.180 165.792 1.00 68.56  ? 583 GLU A CG  1 
ATOM   4262 C  CD  . GLU A 1 583 ? 156.043 111.971 164.291 1.00 68.56  ? 583 GLU A CD  1 
ATOM   4263 O  OE1 . GLU A 1 583 ? 156.959 111.288 163.787 1.00 68.56  ? 583 GLU A OE1 1 
ATOM   4264 O  OE2 . GLU A 1 583 ? 155.132 112.491 163.614 1.00 68.56  ? 583 GLU A OE2 1 
ATOM   4265 N  N   . GLU A 1 584 ? 157.676 108.038 166.243 1.00 73.77  ? 584 GLU A N   1 
ATOM   4266 C  CA  . GLU A 1 584 ? 157.839 106.977 165.251 1.00 73.77  ? 584 GLU A CA  1 
ATOM   4267 C  C   . GLU A 1 584 ? 156.636 106.039 165.224 1.00 73.77  ? 584 GLU A C   1 
ATOM   4268 O  O   . GLU A 1 584 ? 156.158 105.664 164.147 1.00 73.77  ? 584 GLU A O   1 
ATOM   4269 C  CB  . GLU A 1 584 ? 159.123 106.197 165.529 1.00 73.77  ? 584 GLU A CB  1 
ATOM   4270 C  CG  . GLU A 1 584 ? 159.489 106.111 167.001 1.00 73.77  ? 584 GLU A CG  1 
ATOM   4271 C  CD  . GLU A 1 584 ? 160.789 105.369 167.235 1.00 73.77  ? 584 GLU A CD  1 
ATOM   4272 O  OE1 . GLU A 1 584 ? 161.489 105.070 166.245 1.00 73.77  ? 584 GLU A OE1 1 
ATOM   4273 O  OE2 . GLU A 1 584 ? 161.111 105.086 168.408 1.00 73.77  ? 584 GLU A OE2 1 
ATOM   4274 N  N   . GLU A 1 585 ? 156.132 105.649 166.395 1.00 70.84  ? 585 GLU A N   1 
ATOM   4275 C  CA  . GLU A 1 585 ? 154.936 104.818 166.459 1.00 70.84  ? 585 GLU A CA  1 
ATOM   4276 C  C   . GLU A 1 585 ? 153.658 105.643 166.493 1.00 70.84  ? 585 GLU A C   1 
ATOM   4277 O  O   . GLU A 1 585 ? 152.600 105.156 166.070 1.00 70.84  ? 585 GLU A O   1 
ATOM   4278 C  CB  . GLU A 1 585 ? 154.988 103.902 167.685 1.00 70.84  ? 585 GLU A CB  1 
ATOM   4279 C  CG  . GLU A 1 585 ? 156.143 102.911 167.680 1.00 70.84  ? 585 GLU A CG  1 
ATOM   4280 C  CD  . GLU A 1 585 ? 157.392 103.467 168.335 1.00 70.84  ? 585 GLU A CD  1 
ATOM   4281 O  OE1 . GLU A 1 585 ? 157.300 104.531 168.982 1.00 70.84  ? 585 GLU A OE1 1 
ATOM   4282 O  OE2 . GLU A 1 585 ? 158.464 102.839 168.206 1.00 70.84  ? 585 GLU A OE2 1 
ATOM   4283 N  N   . LEU A 1 586 ? 153.738 106.880 166.989 1.00 63.95  ? 586 LEU A N   1 
ATOM   4284 C  CA  . LEU A 1 586 ? 152.584 107.770 166.956 1.00 63.95  ? 586 LEU A CA  1 
ATOM   4285 C  C   . LEU A 1 586 ? 152.176 108.096 165.526 1.00 63.95  ? 586 LEU A C   1 
ATOM   4286 O  O   . LEU A 1 586 ? 150.988 108.289 165.252 1.00 63.95  ? 586 LEU A O   1 
ATOM   4287 C  CB  . LEU A 1 586 ? 152.886 109.050 167.736 1.00 63.95  ? 586 LEU A CB  1 
ATOM   4288 C  CG  . LEU A 1 586 ? 151.732 110.033 167.937 1.00 63.95  ? 586 LEU A CG  1 
ATOM   4289 C  CD1 . LEU A 1 586 ? 151.489 110.277 169.415 1.00 63.95  ? 586 LEU A CD1 1 
ATOM   4290 C  CD2 . LEU A 1 586 ? 152.022 111.340 167.222 1.00 63.95  ? 586 LEU A CD2 1 
ATOM   4291 N  N   . ASP A 1 587 ? 153.143 108.154 164.605 1.00 65.74  ? 587 ASP A N   1 
ATOM   4292 C  CA  . ASP A 1 587 ? 152.822 108.355 163.196 1.00 65.74  ? 587 ASP A CA  1 
ATOM   4293 C  C   . ASP A 1 587 ? 151.995 107.198 162.649 1.00 65.74  ? 587 ASP A C   1 
ATOM   4294 O  O   . ASP A 1 587 ? 151.054 107.410 161.876 1.00 65.74  ? 587 ASP A O   1 
ATOM   4295 C  CB  . ASP A 1 587 ? 154.108 108.524 162.386 1.00 65.74  ? 587 ASP A CB  1 
ATOM   4296 C  CG  . ASP A 1 587 ? 153.867 109.163 161.034 1.00 65.74  ? 587 ASP A CG  1 
ATOM   4297 O  OD1 . ASP A 1 587 ? 153.318 110.283 160.996 1.00 65.74  ? 587 ASP A OD1 1 
ATOM   4298 O  OD2 . ASP A 1 587 ? 154.227 108.547 160.010 1.00 65.74  ? 587 ASP A OD2 1 
ATOM   4299 N  N   . LYS A 1 588 ? 152.342 105.966 163.031 1.00 67.05  ? 588 LYS A N   1 
ATOM   4300 C  CA  . LYS A 1 588 ? 151.532 104.815 162.644 1.00 67.05  ? 588 LYS A CA  1 
ATOM   4301 C  C   . LYS A 1 588 ? 150.148 104.878 163.276 1.00 67.05  ? 588 LYS A C   1 
ATOM   4302 O  O   . LYS A 1 588 ? 149.138 104.625 162.608 1.00 67.05  ? 588 LYS A O   1 
ATOM   4303 C  CB  . LYS A 1 588 ? 152.242 103.518 163.038 1.00 67.05  ? 588 LYS A CB  1 
ATOM   4304 C  CG  . LYS A 1 588 ? 151.310 102.328 163.224 1.00 67.05  ? 588 LYS A CG  1 
ATOM   4305 C  CD  . LYS A 1 588 ? 151.982 101.197 163.983 1.00 67.05  ? 588 LYS A CD  1 
ATOM   4306 C  CE  . LYS A 1 588 ? 151.008 100.057 164.238 1.00 67.05  ? 588 LYS A CE  1 
ATOM   4307 N  NZ  . LYS A 1 588 ? 151.657 98.909  164.928 1.00 67.05  ? 588 LYS A NZ  1 
ATOM   4308 N  N   . LYS A 1 589 ? 150.078 105.234 164.558 1.00 61.19  ? 589 LYS A N   1 
ATOM   4309 C  CA  . LYS A 1 589 ? 148.803 105.247 165.263 1.00 61.19  ? 589 LYS A CA  1 
ATOM   4310 C  C   . LYS A 1 589 ? 147.948 106.470 164.952 1.00 61.19  ? 589 LYS A C   1 
ATOM   4311 O  O   . LYS A 1 589 ? 146.757 106.456 165.276 1.00 61.19  ? 589 LYS A O   1 
ATOM   4312 C  CB  . LYS A 1 589 ? 149.035 105.165 166.774 1.00 61.19  ? 589 LYS A CB  1 
ATOM   4313 C  CG  . LYS A 1 589 ? 149.410 103.782 167.274 1.00 61.19  ? 589 LYS A CG  1 
ATOM   4314 C  CD  . LYS A 1 589 ? 149.367 103.719 168.792 1.00 61.19  ? 589 LYS A CD  1 
ATOM   4315 C  CE  . LYS A 1 589 ? 149.707 102.327 169.299 1.00 61.19  ? 589 LYS A CE  1 
ATOM   4316 N  NZ  . LYS A 1 589 ? 149.545 102.221 170.775 1.00 61.19  ? 589 LYS A NZ  1 
ATOM   4317 N  N   . LEU A 1 590 ? 148.516 107.506 164.326 1.00 57.26  ? 590 LEU A N   1 
ATOM   4318 C  CA  . LEU A 1 590 ? 147.815 108.782 164.179 1.00 57.26  ? 590 LEU A CA  1 
ATOM   4319 C  C   . LEU A 1 590 ? 146.592 108.669 163.277 1.00 57.26  ? 590 LEU A C   1 
ATOM   4320 O  O   . LEU A 1 590 ? 145.565 109.306 163.537 1.00 57.26  ? 590 LEU A O   1 
ATOM   4321 C  CB  . LEU A 1 590 ? 148.768 109.843 163.634 1.00 57.26  ? 590 LEU A CB  1 
ATOM   4322 C  CG  . LEU A 1 590 ? 148.402 111.298 163.912 1.00 57.26  ? 590 LEU A CG  1 
ATOM   4323 C  CD1 . LEU A 1 590 ? 148.841 111.705 165.306 1.00 57.26  ? 590 LEU A CD1 1 
ATOM   4324 C  CD2 . LEU A 1 590 ? 149.045 112.186 162.869 1.00 57.26  ? 590 LEU A CD2 1 
ATOM   4325 N  N   . GLU A 1 591 ? 146.682 107.878 162.208 1.00 61.60  ? 591 GLU A N   1 
ATOM   4326 C  CA  . GLU A 1 591 ? 145.610 107.827 161.221 1.00 61.60  ? 591 GLU A CA  1 
ATOM   4327 C  C   . GLU A 1 591 ? 144.358 107.120 161.725 1.00 61.60  ? 591 GLU A C   1 
ATOM   4328 O  O   . GLU A 1 591 ? 143.331 107.161 161.039 1.00 61.60  ? 591 GLU A O   1 
ATOM   4329 C  CB  . GLU A 1 591 ? 146.106 107.145 159.945 1.00 61.60  ? 591 GLU A CB  1 
ATOM   4330 C  CG  . GLU A 1 591 ? 147.404 107.719 159.403 1.00 61.60  ? 591 GLU A CG  1 
ATOM   4331 C  CD  . GLU A 1 591 ? 147.907 106.973 158.183 1.00 61.60  ? 591 GLU A CD  1 
ATOM   4332 O  OE1 . GLU A 1 591 ? 147.383 105.876 157.898 1.00 61.60  ? 591 GLU A OE1 1 
ATOM   4333 O  OE2 . GLU A 1 591 ? 148.824 107.486 157.508 1.00 61.60  ? 591 GLU A OE2 1 
ATOM   4334 N  N   . HIS A 1 592 ? 144.409 106.475 162.893 1.00 66.54  ? 592 HIS A N   1 
ATOM   4335 C  CA  . HIS A 1 592 ? 143.272 105.723 163.412 1.00 66.54  ? 592 HIS A CA  1 
ATOM   4336 C  C   . HIS A 1 592 ? 142.838 106.199 164.794 1.00 66.54  ? 592 HIS A C   1 
ATOM   4337 O  O   . HIS A 1 592 ? 142.297 105.407 165.572 1.00 66.54  ? 592 HIS A O   1 
ATOM   4338 C  CB  . HIS A 1 592 ? 143.600 104.230 163.453 1.00 66.54  ? 592 HIS A CB  1 
ATOM   4339 C  CG  . HIS A 1 592 ? 143.425 103.537 162.138 1.00 66.54  ? 592 HIS A CG  1 
ATOM   4340 N  ND1 . HIS A 1 592 ? 143.155 104.216 160.969 1.00 66.54  ? 592 HIS A ND1 1 
ATOM   4341 C  CD2 . HIS A 1 592 ? 143.486 102.226 161.806 1.00 66.54  ? 592 HIS A CD2 1 
ATOM   4342 C  CE1 . HIS A 1 592 ? 143.055 103.352 159.974 1.00 66.54  ? 592 HIS A CE1 1 
ATOM   4343 N  NE2 . HIS A 1 592 ? 143.252 102.138 160.455 1.00 66.54  ? 592 HIS A NE2 1 
ATOM   4344 N  N   . ILE A 1 593 ? 143.059 107.470 165.125 1.00 62.95  ? 593 ILE A N   1 
ATOM   4345 C  CA  . ILE A 1 593 ? 142.693 108.002 166.432 1.00 62.95  ? 593 ILE A CA  1 
ATOM   4346 C  C   . ILE A 1 593 ? 142.095 109.392 166.247 1.00 62.95  ? 593 ILE A C   1 
ATOM   4347 O  O   . ILE A 1 593 ? 142.596 110.195 165.452 1.00 62.95  ? 593 ILE A O   1 
ATOM   4348 C  CB  . ILE A 1 593 ? 143.907 108.022 167.389 1.00 62.95  ? 593 ILE A CB  1 
ATOM   4349 C  CG1 . ILE A 1 593 ? 143.589 108.744 168.693 1.00 62.95  ? 593 ILE A CG1 1 
ATOM   4350 C  CG2 . ILE A 1 593 ? 145.093 108.712 166.749 1.00 62.95  ? 593 ILE A CG2 1 
ATOM   4351 C  CD1 . ILE A 1 593 ? 144.697 108.605 169.704 1.00 62.95  ? 593 ILE A CD1 1 
ATOM   4352 N  N   . ALA A 1 594 ? 141.002 109.665 166.963 1.00 54.99  ? 594 ALA A N   1 
ATOM   4353 C  CA  . ALA A 1 594 ? 140.305 110.938 166.847 1.00 54.99  ? 594 ALA A CA  1 
ATOM   4354 C  C   . ALA A 1 594 ? 139.976 111.598 168.179 1.00 54.99  ? 594 ALA A C   1 
ATOM   4355 O  O   . ALA A 1 594 ? 139.529 112.751 168.174 1.00 54.99  ? 594 ALA A O   1 
ATOM   4356 C  CB  . ALA A 1 594 ? 139.004 110.765 166.049 1.00 54.99  ? 594 ALA A CB  1 
ATOM   4357 N  N   . VAL A 1 595 ? 140.176 110.920 169.306 1.00 53.67  ? 595 VAL A N   1 
ATOM   4358 C  CA  . VAL A 1 595 ? 139.860 111.449 170.628 1.00 53.67  ? 595 VAL A CA  1 
ATOM   4359 C  C   . VAL A 1 595 ? 141.140 111.573 171.439 1.00 53.67  ? 595 VAL A C   1 
ATOM   4360 O  O   . VAL A 1 595 ? 141.843 110.579 171.658 1.00 53.67  ? 595 VAL A O   1 
ATOM   4361 C  CB  . VAL A 1 595 ? 138.838 110.567 171.367 1.00 53.67  ? 595 VAL A CB  1 
ATOM   4362 C  CG1 . VAL A 1 595 ? 138.159 111.352 172.463 1.00 53.67  ? 595 VAL A CG1 1 
ATOM   4363 C  CG2 . VAL A 1 595 ? 137.792 110.065 170.395 1.00 53.67  ? 595 VAL A CG2 1 
ATOM   4364 N  N   . TYR A 1 596 ? 141.432 112.790 171.887 1.00 52.82  ? 596 TYR A N   1 
ATOM   4365 C  CA  . TYR A 1 596 ? 142.525 113.067 172.808 1.00 52.82  ? 596 TYR A CA  1 
ATOM   4366 C  C   . TYR A 1 596 ? 141.936 113.611 174.101 1.00 52.82  ? 596 TYR A C   1 
ATOM   4367 O  O   . TYR A 1 596 ? 141.197 114.600 174.080 1.00 52.82  ? 596 TYR A O   1 
ATOM   4368 C  CB  . TYR A 1 596 ? 143.509 114.078 172.213 1.00 52.82  ? 596 TYR A CB  1 
ATOM   4369 C  CG  . TYR A 1 596 ? 144.098 113.682 170.877 1.00 52.82  ? 596 TYR A CG  1 
ATOM   4370 C  CD1 . TYR A 1 596 ? 144.473 112.374 170.615 1.00 52.82  ? 596 TYR A CD1 1 
ATOM   4371 C  CD2 . TYR A 1 596 ? 144.262 114.620 169.869 1.00 52.82  ? 596 TYR A CD2 1 
ATOM   4372 C  CE1 . TYR A 1 596 ? 145.010 112.022 169.391 1.00 52.82  ? 596 TYR A CE1 1 
ATOM   4373 C  CE2 . TYR A 1 596 ? 144.793 114.274 168.646 1.00 52.82  ? 596 TYR A CE2 1 
ATOM   4374 C  CZ  . TYR A 1 596 ? 145.165 112.974 168.411 1.00 52.82  ? 596 TYR A CZ  1 
ATOM   4375 O  OH  . TYR A 1 596 ? 145.695 112.624 167.191 1.00 52.82  ? 596 TYR A OH  1 
ATOM   4376 N  N   . ALA A 1 597 ? 142.256 112.968 175.220 1.00 64.78  ? 597 ALA A N   1 
ATOM   4377 C  CA  . ALA A 1 597 ? 141.779 113.399 176.524 1.00 64.78  ? 597 ALA A CA  1 
ATOM   4378 C  C   . ALA A 1 597 ? 142.956 113.784 177.407 1.00 64.78  ? 597 ALA A C   1 
ATOM   4379 O  O   . ALA A 1 597 ? 144.056 113.238 177.270 1.00 64.78  ? 597 ALA A O   1 
ATOM   4380 C  CB  . ALA A 1 597 ? 140.949 112.315 177.212 1.00 64.78  ? 597 ALA A CB  1 
ATOM   4381 N  N   . ARG A 1 598 ? 142.701 114.730 178.317 1.00 71.06  ? 598 ARG A N   1 
ATOM   4382 C  CA  . ARG A 1 598 ? 143.727 115.312 179.188 1.00 71.06  ? 598 ARG A CA  1 
ATOM   4383 C  C   . ARG A 1 598 ? 144.889 115.863 178.366 1.00 71.06  ? 598 ARG A C   1 
ATOM   4384 O  O   . ARG A 1 598 ? 146.061 115.701 178.712 1.00 71.06  ? 598 ARG A O   1 
ATOM   4385 C  CB  . ARG A 1 598 ? 144.214 114.300 180.230 1.00 71.06  ? 598 ARG A CB  1 
ATOM   4386 C  CG  . ARG A 1 598 ? 143.096 113.541 180.932 1.00 71.06  ? 598 ARG A CG  1 
ATOM   4387 C  CD  . ARG A 1 598 ? 142.411 114.408 181.975 1.00 71.06  ? 598 ARG A CD  1 
ATOM   4388 N  NE  . ARG A 1 598 ? 141.374 113.682 182.700 1.00 71.06  ? 598 ARG A NE  1 
ATOM   4389 C  CZ  . ARG A 1 598 ? 140.869 114.063 183.865 1.00 71.06  ? 598 ARG A CZ  1 
ATOM   4390 N  NH1 . ARG A 1 598 ? 141.278 115.166 184.469 1.00 71.06  ? 598 ARG A NH1 1 
ATOM   4391 N  NH2 . ARG A 1 598 ? 139.928 113.318 184.438 1.00 71.06  ? 598 ARG A NH2 1 
ATOM   4392 N  N   . VAL A 1 599 ? 144.552 116.522 177.259 1.00 70.79  ? 599 VAL A N   1 
ATOM   4393 C  CA  . VAL A 1 599 ? 145.562 117.010 176.330 1.00 70.79  ? 599 VAL A CA  1 
ATOM   4394 C  C   . VAL A 1 599 ? 146.197 118.286 176.877 1.00 70.79  ? 599 VAL A C   1 
ATOM   4395 O  O   . VAL A 1 599 ? 145.666 118.949 177.772 1.00 70.79  ? 599 VAL A O   1 
ATOM   4396 C  CB  . VAL A 1 599 ? 144.948 117.233 174.933 1.00 70.79  ? 599 VAL A CB  1 
ATOM   4397 C  CG1 . VAL A 1 599 ? 144.313 118.615 174.826 1.00 70.79  ? 599 VAL A CG1 1 
ATOM   4398 C  CG2 . VAL A 1 599 ? 145.981 117.005 173.835 1.00 70.79  ? 599 VAL A CG2 1 
ATOM   4399 N  N   . SER A 1 600 ? 147.359 118.622 176.336 1.00 72.91  ? 600 SER A N   1 
ATOM   4400 C  CA  . SER A 1 600 ? 148.124 119.799 176.712 1.00 72.91  ? 600 SER A CA  1 
ATOM   4401 C  C   . SER A 1 600 ? 148.488 120.576 175.458 1.00 72.91  ? 600 SER A C   1 
ATOM   4402 O  O   . SER A 1 600 ? 148.501 120.018 174.356 1.00 72.91  ? 600 SER A O   1 
ATOM   4403 C  CB  . SER A 1 600 ? 149.398 119.409 177.478 1.00 72.91  ? 600 SER A CB  1 
ATOM   4404 O  OG  . SER A 1 600 ? 150.334 118.777 176.623 1.00 72.91  ? 600 SER A OG  1 
ATOM   4405 N  N   . PRO A 1 601 ? 148.750 121.882 175.586 1.00 71.27  ? 601 PRO A N   1 
ATOM   4406 C  CA  . PRO A 1 601 ? 149.203 122.654 174.416 1.00 71.27  ? 601 PRO A CA  1 
ATOM   4407 C  C   . PRO A 1 601 ? 150.492 122.139 173.800 1.00 71.27  ? 601 PRO A C   1 
ATOM   4408 O  O   . PRO A 1 601 ? 150.671 122.255 172.581 1.00 71.27  ? 601 PRO A O   1 
ATOM   4409 C  CB  . PRO A 1 601 ? 149.369 124.069 174.984 1.00 71.27  ? 601 PRO A CB  1 
ATOM   4410 C  CG  . PRO A 1 601 ? 148.375 124.125 176.088 1.00 71.27  ? 601 PRO A CG  1 
ATOM   4411 C  CD  . PRO A 1 601 ? 148.389 122.759 176.714 1.00 71.27  ? 601 PRO A CD  1 
ATOM   4412 N  N   . GLU A 1 602 ? 151.404 121.584 174.601 1.00 73.60  ? 602 GLU A N   1 
ATOM   4413 C  CA  . GLU A 1 602 ? 152.554 120.890 174.028 1.00 73.60  ? 602 GLU A CA  1 
ATOM   4414 C  C   . GLU A 1 602 ? 152.108 119.668 173.236 1.00 73.60  ? 602 GLU A C   1 
ATOM   4415 O  O   . GLU A 1 602 ? 152.611 119.409 172.135 1.00 73.60  ? 602 GLU A O   1 
ATOM   4416 C  CB  . GLU A 1 602 ? 153.533 120.493 175.133 1.00 73.60  ? 602 GLU A CB  1 
ATOM   4417 C  CG  . GLU A 1 602 ? 154.526 121.585 175.499 1.00 73.60  ? 602 GLU A CG  1 
ATOM   4418 C  CD  . GLU A 1 602 ? 153.915 122.658 176.380 1.00 73.60  ? 602 GLU A CD  1 
ATOM   4419 O  OE1 . GLU A 1 602 ? 152.920 122.363 177.075 1.00 73.60  ? 602 GLU A OE1 1 
ATOM   4420 O  OE2 . GLU A 1 602 ? 154.430 123.796 176.377 1.00 73.60  ? 602 GLU A OE2 1 
ATOM   4421 N  N   . ASN A 1 603 ? 151.144 118.914 173.769 1.00 70.66  ? 603 ASN A N   1 
ATOM   4422 C  CA  . ASN A 1 603 ? 150.564 117.815 173.007 1.00 70.66  ? 603 ASN A CA  1 
ATOM   4423 C  C   . ASN A 1 603 ? 149.772 118.322 171.809 1.00 70.66  ? 603 ASN A C   1 
ATOM   4424 O  O   . ASN A 1 603 ? 149.667 117.619 170.799 1.00 70.66  ? 603 ASN A O   1 
ATOM   4425 C  CB  . ASN A 1 603 ? 149.681 116.955 173.910 1.00 70.66  ? 603 ASN A CB  1 
ATOM   4426 C  CG  . ASN A 1 603 ? 150.483 116.164 174.923 1.00 70.66  ? 603 ASN A CG  1 
ATOM   4427 O  OD1 . ASN A 1 603 ? 150.402 116.411 176.126 1.00 70.66  ? 603 ASN A OD1 1 
ATOM   4428 N  ND2 . ASN A 1 603 ? 151.267 115.208 174.440 1.00 70.66  ? 603 ASN A ND2 1 
ATOM   4429 N  N   . LYS A 1 604 ? 149.211 119.532 171.897 1.00 67.86  ? 604 LYS A N   1 
ATOM   4430 C  CA  . LYS A 1 604 ? 148.564 120.134 170.735 1.00 67.86  ? 604 LYS A CA  1 
ATOM   4431 C  C   . LYS A 1 604 ? 149.575 120.413 169.627 1.00 67.86  ? 604 LYS A C   1 
ATOM   4432 O  O   . LYS A 1 604 ? 149.311 120.140 168.449 1.00 67.86  ? 604 LYS A O   1 
ATOM   4433 C  CB  . LYS A 1 604 ? 147.840 121.416 171.145 1.00 67.86  ? 604 LYS A CB  1 
ATOM   4434 C  CG  . LYS A 1 604 ? 146.529 121.179 171.877 1.00 67.86  ? 604 LYS A CG  1 
ATOM   4435 C  CD  . LYS A 1 604 ? 145.994 122.464 172.487 1.00 67.86  ? 604 LYS A CD  1 
ATOM   4436 C  CE  . LYS A 1 604 ? 145.725 123.512 171.420 1.00 67.86  ? 604 LYS A CE  1 
ATOM   4437 N  NZ  . LYS A 1 604 ? 144.538 123.169 170.590 1.00 67.86  ? 604 LYS A NZ  1 
ATOM   4438 N  N   . ILE A 1 605 ? 150.742 120.950 169.996 1.00 64.39  ? 605 ILE A N   1 
ATOM   4439 C  CA  . ILE A 1 605 ? 151.845 121.113 169.049 1.00 64.39  ? 605 ILE A CA  1 
ATOM   4440 C  C   . ILE A 1 605 ? 152.233 119.765 168.457 1.00 64.39  ? 605 ILE A C   1 
ATOM   4441 O  O   . ILE A 1 605 ? 152.435 119.631 167.242 1.00 64.39  ? 605 ILE A O   1 
ATOM   4442 C  CB  . ILE A 1 605 ? 153.040 121.797 169.741 1.00 64.39  ? 605 ILE A CB  1 
ATOM   4443 C  CG1 . ILE A 1 605 ? 152.912 123.315 169.655 1.00 64.39  ? 605 ILE A CG1 1 
ATOM   4444 C  CG2 . ILE A 1 605 ? 154.370 121.361 169.131 1.00 64.39  ? 605 ILE A CG2 1 
ATOM   4445 C  CD1 . ILE A 1 605 ? 152.925 123.821 168.237 1.00 64.39  ? 605 ILE A CD1 1 
ATOM   4446 N  N   . ARG A 1 606 ? 152.319 118.742 169.311 1.00 61.97  ? 606 ARG A N   1 
ATOM   4447 C  CA  . ARG A 1 606 ? 152.712 117.411 168.862 1.00 61.97  ? 606 ARG A CA  1 
ATOM   4448 C  C   . ARG A 1 606 ? 151.738 116.860 167.827 1.00 61.97  ? 606 ARG A C   1 
ATOM   4449 O  O   . ARG A 1 606 ? 152.151 116.369 166.770 1.00 61.97  ? 606 ARG A O   1 
ATOM   4450 C  CB  . ARG A 1 606 ? 152.807 116.472 170.064 1.00 61.97  ? 606 ARG A CB  1 
ATOM   4451 C  CG  . ARG A 1 606 ? 153.199 115.054 169.715 1.00 61.97  ? 606 ARG A CG  1 
ATOM   4452 C  CD  . ARG A 1 606 ? 153.966 114.404 170.853 1.00 61.97  ? 606 ARG A CD  1 
ATOM   4453 N  NE  . ARG A 1 606 ? 154.013 112.955 170.711 1.00 61.97  ? 606 ARG A NE  1 
ATOM   4454 C  CZ  . ARG A 1 606 ? 154.830 112.309 169.891 1.00 61.97  ? 606 ARG A CZ  1 
ATOM   4455 N  NH1 . ARG A 1 606 ? 155.704 112.954 169.135 1.00 61.97  ? 606 ARG A NH1 1 
ATOM   4456 N  NH2 . ARG A 1 606 ? 154.770 110.983 169.829 1.00 61.97  ? 606 ARG A NH2 1 
ATOM   4457 N  N   . ILE A 1 607 ? 150.434 116.960 168.100 1.00 61.39  ? 607 ILE A N   1 
ATOM   4458 C  CA  . ILE A 1 607 ? 149.454 116.366 167.196 1.00 61.39  ? 607 ILE A CA  1 
ATOM   4459 C  C   . ILE A 1 607 ? 149.343 117.172 165.907 1.00 61.39  ? 607 ILE A C   1 
ATOM   4460 O  O   . ILE A 1 607 ? 149.178 116.596 164.825 1.00 61.39  ? 607 ILE A O   1 
ATOM   4461 C  CB  . ILE A 1 607 ? 148.087 116.191 167.887 1.00 61.39  ? 607 ILE A CB  1 
ATOM   4462 C  CG1 . ILE A 1 607 ? 147.523 117.528 168.377 1.00 61.39  ? 607 ILE A CG1 1 
ATOM   4463 C  CG2 . ILE A 1 607 ? 148.207 115.187 169.018 1.00 61.39  ? 607 ILE A CG2 1 
ATOM   4464 C  CD1 . ILE A 1 607 ? 146.427 117.411 169.414 1.00 61.39  ? 607 ILE A CD1 1 
ATOM   4465 N  N   . VAL A 1 608 ? 149.445 118.506 165.982 1.00 59.65  ? 608 VAL A N   1 
ATOM   4466 C  CA  . VAL A 1 608 ? 149.344 119.285 164.750 1.00 59.65  ? 608 VAL A CA  1 
ATOM   4467 C  C   . VAL A 1 608 ? 150.574 119.058 163.873 1.00 59.65  ? 608 VAL A C   1 
ATOM   4468 O  O   . VAL A 1 608 ? 150.460 118.959 162.646 1.00 59.65  ? 608 VAL A O   1 
ATOM   4469 C  CB  . VAL A 1 608 ? 149.091 120.780 165.045 1.00 59.65  ? 608 VAL A CB  1 
ATOM   4470 C  CG1 . VAL A 1 608 ? 150.288 121.466 165.687 1.00 59.65  ? 608 VAL A CG1 1 
ATOM   4471 C  CG2 . VAL A 1 608 ? 148.674 121.505 163.774 1.00 59.65  ? 608 VAL A CG2 1 
ATOM   4472 N  N   . LYS A 1 609 ? 151.757 118.908 164.482 1.00 58.66  ? 609 LYS A N   1 
ATOM   4473 C  CA  . LYS A 1 609 ? 152.952 118.619 163.695 1.00 58.66  ? 609 LYS A CA  1 
ATOM   4474 C  C   . LYS A 1 609 ? 152.903 117.214 163.107 1.00 58.66  ? 609 LYS A C   1 
ATOM   4475 O  O   . LYS A 1 609 ? 153.317 117.001 161.960 1.00 58.66  ? 609 LYS A O   1 
ATOM   4476 C  CB  . LYS A 1 609 ? 154.204 118.803 164.553 1.00 58.66  ? 609 LYS A CB  1 
ATOM   4477 C  CG  . LYS A 1 609 ? 154.540 120.257 164.850 1.00 58.66  ? 609 LYS A CG  1 
ATOM   4478 C  CD  . LYS A 1 609 ? 154.989 120.989 163.597 1.00 58.66  ? 609 LYS A CD  1 
ATOM   4479 C  CE  . LYS A 1 609 ? 156.432 120.661 163.257 1.00 58.66  ? 609 LYS A CE  1 
ATOM   4480 N  NZ  . LYS A 1 609 ? 157.352 120.991 164.380 1.00 58.66  ? 609 LYS A NZ  1 
ATOM   4481 N  N   . ALA A 1 610 ? 152.395 116.242 163.872 1.00 56.91  ? 610 ALA A N   1 
ATOM   4482 C  CA  . ALA A 1 610 ? 152.283 114.881 163.360 1.00 56.91  ? 610 ALA A CA  1 
ATOM   4483 C  C   . ALA A 1 610 ? 151.280 114.799 162.217 1.00 56.91  ? 610 ALA A C   1 
ATOM   4484 O  O   . ALA A 1 610 ? 151.495 114.062 161.248 1.00 56.91  ? 610 ALA A O   1 
ATOM   4485 C  CB  . ALA A 1 610 ? 151.896 113.926 164.487 1.00 56.91  ? 610 ALA A CB  1 
ATOM   4486 N  N   . TRP A 1 611 ? 150.174 115.542 162.312 1.00 56.21  ? 611 TRP A N   1 
ATOM   4487 C  CA  . TRP A 1 611 ? 149.213 115.566 161.216 1.00 56.21  ? 611 TRP A CA  1 
ATOM   4488 C  C   . TRP A 1 611 ? 149.774 116.303 160.007 1.00 56.21  ? 611 TRP A C   1 
ATOM   4489 O  O   . TRP A 1 611 ? 149.493 115.928 158.864 1.00 56.21  ? 611 TRP A O   1 
ATOM   4490 C  CB  . TRP A 1 611 ? 147.900 116.199 161.681 1.00 56.21  ? 611 TRP A CB  1 
ATOM   4491 C  CG  . TRP A 1 611 ? 146.906 115.215 162.253 1.00 56.21  ? 611 TRP A CG  1 
ATOM   4492 C  CD1 . TRP A 1 611 ? 146.280 115.303 163.461 1.00 56.21  ? 611 TRP A CD1 1 
ATOM   4493 C  CD2 . TRP A 1 611 ? 146.391 114.030 161.623 1.00 56.21  ? 611 TRP A CD2 1 
ATOM   4494 N  NE1 . TRP A 1 611 ? 145.433 114.237 163.638 1.00 56.21  ? 611 TRP A NE1 1 
ATOM   4495 C  CE2 . TRP A 1 611 ? 145.483 113.441 162.524 1.00 56.21  ? 611 TRP A CE2 1 
ATOM   4496 C  CE3 . TRP A 1 611 ? 146.622 113.403 160.393 1.00 56.21  ? 611 TRP A CE3 1 
ATOM   4497 C  CZ2 . TRP A 1 611 ? 144.801 112.261 162.233 1.00 56.21  ? 611 TRP A CZ2 1 
ATOM   4498 C  CZ3 . TRP A 1 611 ? 145.947 112.229 160.109 1.00 56.21  ? 611 TRP A CZ3 1 
ATOM   4499 C  CH2 . TRP A 1 611 ? 145.047 111.672 161.024 1.00 56.21  ? 611 TRP A CH2 1 
ATOM   4500 N  N   . GLN A 1 612 ? 150.575 117.347 160.236 1.00 57.34  ? 612 GLN A N   1 
ATOM   4501 C  CA  . GLN A 1 612 ? 151.188 118.075 159.132 1.00 57.34  ? 612 GLN A CA  1 
ATOM   4502 C  C   . GLN A 1 612 ? 152.288 117.282 158.442 1.00 57.34  ? 612 GLN A C   1 
ATOM   4503 O  O   . GLN A 1 612 ? 152.578 117.550 157.271 1.00 57.34  ? 612 GLN A O   1 
ATOM   4504 C  CB  . GLN A 1 612 ? 151.762 119.398 159.633 1.00 57.34  ? 612 GLN A CB  1 
ATOM   4505 C  CG  . GLN A 1 612 ? 150.759 120.524 159.722 1.00 57.34  ? 612 GLN A CG  1 
ATOM   4506 C  CD  . GLN A 1 612 ? 151.336 121.745 160.400 1.00 57.34  ? 612 GLN A CD  1 
ATOM   4507 O  OE1 . GLN A 1 612 ? 152.487 121.742 160.836 1.00 57.34  ? 612 GLN A OE1 1 
ATOM   4508 N  NE2 . GLN A 1 612 ? 150.544 122.802 160.484 1.00 57.34  ? 612 GLN A NE2 1 
ATOM   4509 N  N   . LYS A 1 613 ? 152.918 116.335 159.144 1.00 57.25  ? 613 LYS A N   1 
ATOM   4510 C  CA  . LYS A 1 613 ? 154.068 115.629 158.583 1.00 57.25  ? 613 LYS A CA  1 
ATOM   4511 C  C   . LYS A 1 613 ? 153.687 114.814 157.351 1.00 57.25  ? 613 LYS A C   1 
ATOM   4512 O  O   . LYS A 1 613 ? 154.395 114.842 156.337 1.00 57.25  ? 613 LYS A O   1 
ATOM   4513 C  CB  . LYS A 1 613 ? 154.700 114.734 159.650 1.00 57.25  ? 613 LYS A CB  1 
ATOM   4514 C  CG  . LYS A 1 613 ? 155.736 113.753 159.121 1.00 57.25  ? 613 LYS A CG  1 
ATOM   4515 C  CD  . LYS A 1 613 ? 155.246 112.316 159.206 1.00 57.25  ? 613 LYS A CD  1 
ATOM   4516 C  CE  . LYS A 1 613 ? 156.093 111.392 158.347 1.00 57.25  ? 613 LYS A CE  1 
ATOM   4517 N  NZ  . LYS A 1 613 ? 155.643 109.975 158.442 1.00 57.25  ? 613 LYS A NZ  1 
ATOM   4518 N  N   . LYS A 1 614 ? 152.575 114.088 157.412 1.00 54.92  ? 614 LYS A N   1 
ATOM   4519 C  CA  . LYS A 1 614 ? 152.143 113.246 156.295 1.00 54.92  ? 614 LYS A CA  1 
ATOM   4520 C  C   . LYS A 1 614 ? 151.176 113.983 155.372 1.00 54.92  ? 614 LYS A C   1 
ATOM   4521 O  O   . LYS A 1 614 ? 150.123 113.462 155.011 1.00 54.92  ? 614 LYS A O   1 
ATOM   4522 C  CB  . LYS A 1 614 ? 151.512 111.967 156.833 1.00 54.92  ? 614 LYS A CB  1 
ATOM   4523 C  CG  . LYS A 1 614 ? 150.502 112.203 157.949 1.00 54.92  ? 614 LYS A CG  1 
ATOM   4524 C  CD  . LYS A 1 614 ? 149.726 110.940 158.274 1.00 54.92  ? 614 LYS A CD  1 
ATOM   4525 C  CE  . LYS A 1 614 ? 150.580 109.954 159.045 1.00 54.92  ? 614 LYS A CE  1 
ATOM   4526 N  NZ  . LYS A 1 614 ? 151.062 110.551 160.319 1.00 54.92  ? 614 LYS A NZ  1 
ATOM   4527 N  N   . GLY A 1 615 ? 151.546 115.186 154.939 1.00 54.92  ? 615 GLY A N   1 
ATOM   4528 C  CA  . GLY A 1 615 ? 150.596 116.043 154.256 1.00 54.92  ? 615 GLY A CA  1 
ATOM   4529 C  C   . GLY A 1 615 ? 149.484 116.433 155.207 1.00 54.92  ? 615 GLY A C   1 
ATOM   4530 O  O   . GLY A 1 615 ? 149.766 116.971 156.281 1.00 54.92  ? 615 GLY A O   1 
ATOM   4531 N  N   . LYS A 1 616 ? 148.229 116.174 154.822 1.00 54.14  ? 616 LYS A N   1 
ATOM   4532 C  CA  . LYS A 1 616 ? 147.071 116.214 155.722 1.00 54.14  ? 616 LYS A CA  1 
ATOM   4533 C  C   . LYS A 1 616 ? 146.932 117.586 156.392 1.00 54.14  ? 616 LYS A C   1 
ATOM   4534 O  O   . LYS A 1 616 ? 147.190 117.751 157.587 1.00 54.14  ? 616 LYS A O   1 
ATOM   4535 C  CB  . LYS A 1 616 ? 147.153 115.098 156.771 1.00 54.14  ? 616 LYS A CB  1 
ATOM   4536 C  CG  . LYS A 1 616 ? 147.157 113.687 156.202 1.00 54.14  ? 616 LYS A CG  1 
ATOM   4537 C  CD  . LYS A 1 616 ? 146.019 113.463 155.226 1.00 54.14  ? 616 LYS A CD  1 
ATOM   4538 C  CE  . LYS A 1 616 ? 145.690 111.986 155.092 1.00 54.14  ? 616 LYS A CE  1 
ATOM   4539 N  NZ  . LYS A 1 616 ? 145.021 111.454 156.311 1.00 54.14  ? 616 LYS A NZ  1 
ATOM   4540 N  N   . ILE A 1 617 ? 146.581 118.575 155.559 1.00 53.96  ? 617 ILE A N   1 
ATOM   4541 C  CA  . ILE A 1 617 ? 146.464 119.964 155.998 1.00 53.96  ? 617 ILE A CA  1 
ATOM   4542 C  C   . ILE A 1 617 ? 145.563 120.059 157.220 1.00 53.96  ? 617 ILE A C   1 
ATOM   4543 O  O   . ILE A 1 617 ? 144.424 119.581 157.214 1.00 53.96  ? 617 ILE A O   1 
ATOM   4544 C  CB  . ILE A 1 617 ? 145.940 120.841 154.847 1.00 53.96  ? 617 ILE A CB  1 
ATOM   4545 C  CG1 . ILE A 1 617 ? 146.822 120.680 153.608 1.00 53.96  ? 617 ILE A CG1 1 
ATOM   4546 C  CG2 . ILE A 1 617 ? 145.879 122.297 155.273 1.00 53.96  ? 617 ILE A CG2 1 
ATOM   4547 C  CD1 . ILE A 1 617 ? 148.282 120.999 153.847 1.00 53.96  ? 617 ILE A CD1 1 
ATOM   4548 N  N   . THR A 1 618 ? 146.081 120.677 158.277 1.00 56.06  ? 618 THR A N   1 
ATOM   4549 C  CA  . THR A 1 618 ? 145.469 120.671 159.597 1.00 56.06  ? 618 THR A CA  1 
ATOM   4550 C  C   . THR A 1 618 ? 144.794 122.007 159.892 1.00 56.06  ? 618 THR A C   1 
ATOM   4551 O  O   . THR A 1 618 ? 145.154 123.050 159.342 1.00 56.06  ? 618 THR A O   1 
ATOM   4552 C  CB  . THR A 1 618 ? 146.524 120.371 160.668 1.00 56.06  ? 618 THR A CB  1 
ATOM   4553 O  OG1 . THR A 1 618 ? 147.555 121.364 160.612 1.00 56.06  ? 618 THR A OG1 1 
ATOM   4554 C  CG2 . THR A 1 618 ? 147.150 119.000 160.454 1.00 56.06  ? 618 THR A CG2 1 
ATOM   4555 N  N   . ALA A 1 619 ? 143.796 121.957 160.777 1.00 56.21  ? 619 ALA A N   1 
ATOM   4556 C  CA  . ALA A 1 619 ? 143.090 123.149 161.256 1.00 56.21  ? 619 ALA A CA  1 
ATOM   4557 C  C   . ALA A 1 619 ? 142.917 122.998 162.768 1.00 56.21  ? 619 ALA A C   1 
ATOM   4558 O  O   . ALA A 1 619 ? 142.003 122.312 163.233 1.00 56.21  ? 619 ALA A O   1 
ATOM   4559 C  CB  . ALA A 1 619 ? 141.754 123.327 160.547 1.00 56.21  ? 619 ALA A CB  1 
ATOM   4560 N  N   . MET A 1 620 ? 143.802 123.642 163.527 1.00 64.03  ? 620 MET A N   1 
ATOM   4561 C  CA  . MET A 1 620 ? 143.741 123.584 164.979 1.00 64.03  ? 620 MET A CA  1 
ATOM   4562 C  C   . MET A 1 620 ? 142.537 124.373 165.494 1.00 64.03  ? 620 MET A C   1 
ATOM   4563 O  O   . MET A 1 620 ? 141.857 125.082 164.751 1.00 64.03  ? 620 MET A O   1 
ATOM   4564 C  CB  . MET A 1 620 ? 145.031 124.123 165.594 1.00 64.03  ? 620 MET A CB  1 
ATOM   4565 C  CG  . MET A 1 620 ? 145.492 123.356 166.818 1.00 64.03  ? 620 MET A CG  1 
ATOM   4566 S  SD  . MET A 1 620 ? 145.366 121.580 166.555 1.00 64.03  ? 620 MET A SD  1 
ATOM   4567 C  CE  . MET A 1 620 ? 145.735 120.961 168.191 1.00 64.03  ? 620 MET A CE  1 
ATOM   4568 N  N   . THR A 1 621 ? 142.286 124.253 166.798 1.00 62.77  ? 621 THR A N   1 
ATOM   4569 C  CA  . THR A 1 621 ? 141.073 124.788 167.398 1.00 62.77  ? 621 THR A CA  1 
ATOM   4570 C  C   . THR A 1 621 ? 141.280 125.568 168.688 1.00 62.77  ? 621 THR A C   1 
ATOM   4571 O  O   . THR A 1 621 ? 140.307 126.131 169.204 1.00 62.77  ? 621 THR A O   1 
ATOM   4572 C  CB  . THR A 1 621 ? 140.081 123.651 167.670 1.00 62.77  ? 621 THR A CB  1 
ATOM   4573 O  OG1 . THR A 1 621 ? 138.739 124.154 167.657 1.00 62.77  ? 621 THR A OG1 1 
ATOM   4574 C  CG2 . THR A 1 621 ? 140.395 122.964 168.996 1.00 62.77  ? 621 THR A CG2 1 
ATOM   4575 N  N   . GLY A 1 622 ? 142.502 125.627 169.214 1.00 72.63  ? 622 GLY A N   1 
ATOM   4576 C  CA  . GLY A 1 622 ? 142.749 126.182 170.533 1.00 72.63  ? 622 GLY A CA  1 
ATOM   4577 C  C   . GLY A 1 622 ? 142.280 127.607 170.743 1.00 72.63  ? 622 GLY A C   1 
ATOM   4578 O  O   . GLY A 1 622 ? 142.584 128.502 169.950 1.00 72.63  ? 622 GLY A O   1 
ATOM   4579 N  N   . ASP A 1 623 ? 141.517 127.819 171.812 1.00 75.11  ? 623 ASP A N   1 
ATOM   4580 C  CA  . ASP A 1 623 ? 141.027 129.138 172.171 1.00 75.11  ? 623 ASP A CA  1 
ATOM   4581 C  C   . ASP A 1 623 ? 141.746 129.728 173.373 1.00 75.11  ? 623 ASP A C   1 
ATOM   4582 O  O   . ASP A 1 623 ? 141.606 130.928 173.631 1.00 75.11  ? 623 ASP A O   1 
ATOM   4583 C  CB  . ASP A 1 623 ? 139.519 129.087 172.456 1.00 75.11  ? 623 ASP A CB  1 
ATOM   4584 C  CG  . ASP A 1 623 ? 139.132 127.915 173.336 1.00 75.11  ? 623 ASP A CG  1 
ATOM   4585 O  OD1 . ASP A 1 623 ? 139.429 127.956 174.549 1.00 75.11  ? 623 ASP A OD1 1 
ATOM   4586 O  OD2 . ASP A 1 623 ? 138.532 126.951 172.816 1.00 75.11  ? 623 ASP A OD2 1 
ATOM   4587 N  N   . GLY A 1 624 ? 142.510 128.921 174.107 1.00 81.04  ? 624 GLY A N   1 
ATOM   4588 C  CA  . GLY A 1 624 ? 143.221 129.408 175.266 1.00 81.04  ? 624 GLY A CA  1 
ATOM   4589 C  C   . GLY A 1 624 ? 144.402 130.283 174.902 1.00 81.04  ? 624 GLY A C   1 
ATOM   4590 O  O   . GLY A 1 624 ? 144.790 130.414 173.741 1.00 81.04  ? 624 GLY A O   1 
ATOM   4591 N  N   . VAL A 1 625 ? 144.974 130.901 175.936 1.00 91.20  ? 625 VAL A N   1 
ATOM   4592 C  CA  . VAL A 1 625 ? 146.060 131.852 175.732 1.00 91.20  ? 625 VAL A CA  1 
ATOM   4593 C  C   . VAL A 1 625 ? 147.324 131.142 175.269 1.00 91.20  ? 625 VAL A C   1 
ATOM   4594 O  O   . VAL A 1 625 ? 147.983 131.574 174.316 1.00 91.20  ? 625 VAL A O   1 
ATOM   4595 C  CB  . VAL A 1 625 ? 146.309 132.647 177.023 1.00 91.20  ? 625 VAL A CB  1 
ATOM   4596 C  CG1 . VAL A 1 625 ? 147.269 133.783 176.755 1.00 91.20  ? 625 VAL A CG1 1 
ATOM   4597 C  CG2 . VAL A 1 625 ? 144.998 133.141 177.593 1.00 91.20  ? 625 VAL A CG2 1 
ATOM   4598 N  N   . ASN A 1 626 ? 147.682 130.046 175.930 1.00 82.90  ? 626 ASN A N   1 
ATOM   4599 C  CA  . ASN A 1 626 ? 148.901 129.314 175.622 1.00 82.90  ? 626 ASN A CA  1 
ATOM   4600 C  C   . ASN A 1 626 ? 148.707 128.277 174.523 1.00 82.90  ? 626 ASN A C   1 
ATOM   4601 O  O   . ASN A 1 626 ? 149.638 127.518 174.234 1.00 82.90  ? 626 ASN A O   1 
ATOM   4602 C  CB  . ASN A 1 626 ? 149.456 128.668 176.898 1.00 82.90  ? 626 ASN A CB  1 
ATOM   4603 C  CG  . ASN A 1 626 ? 148.645 127.473 177.361 1.00 82.90  ? 626 ASN A CG  1 
ATOM   4604 O  OD1 . ASN A 1 626 ? 147.442 127.381 177.112 1.00 82.90  ? 626 ASN A OD1 1 
ATOM   4605 N  ND2 . ASN A 1 626 ? 149.299 126.562 178.071 1.00 82.90  ? 626 ASN A ND2 1 
ATOM   4606 N  N   . ASP A 1 627 ? 147.524 128.228 173.910 1.00 77.94  ? 627 ASP A N   1 
ATOM   4607 C  CA  . ASP A 1 627 ? 147.312 127.450 172.698 1.00 77.94  ? 627 ASP A CA  1 
ATOM   4608 C  C   . ASP A 1 627 ? 147.862 128.142 171.458 1.00 77.94  ? 627 ASP A C   1 
ATOM   4609 O  O   . ASP A 1 627 ? 147.873 127.530 170.385 1.00 77.94  ? 627 ASP A O   1 
ATOM   4610 C  CB  . ASP A 1 627 ? 145.819 127.171 172.505 1.00 77.94  ? 627 ASP A CB  1 
ATOM   4611 C  CG  . ASP A 1 627 ? 145.277 126.176 173.510 1.00 77.94  ? 627 ASP A CG  1 
ATOM   4612 O  OD1 . ASP A 1 627 ? 146.089 125.491 174.167 1.00 77.94  ? 627 ASP A OD1 1 
ATOM   4613 O  OD2 . ASP A 1 627 ? 144.039 126.082 173.648 1.00 77.94  ? 627 ASP A OD2 1 
ATOM   4614 N  N   . ALA A 1 628 ? 148.306 129.393 171.590 1.00 73.64  ? 628 ALA A N   1 
ATOM   4615 C  CA  . ALA A 1 628 ? 148.797 130.155 170.443 1.00 73.64  ? 628 ALA A CA  1 
ATOM   4616 C  C   . ALA A 1 628 ? 149.949 129.500 169.681 1.00 73.64  ? 628 ALA A C   1 
ATOM   4617 O  O   . ALA A 1 628 ? 149.952 129.602 168.441 1.00 73.64  ? 628 ALA A O   1 
ATOM   4618 C  CB  . ALA A 1 628 ? 149.179 131.572 170.895 1.00 73.64  ? 628 ALA A CB  1 
ATOM   4619 N  N   . PRO A 1 629 ? 150.958 128.869 170.313 1.00 71.85  ? 629 PRO A N   1 
ATOM   4620 C  CA  . PRO A 1 629 ? 151.940 128.125 169.502 1.00 71.85  ? 629 PRO A CA  1 
ATOM   4621 C  C   . PRO A 1 629 ? 151.324 127.023 168.657 1.00 71.85  ? 629 PRO A C   1 
ATOM   4622 O  O   . PRO A 1 629 ? 151.776 126.791 167.529 1.00 71.85  ? 629 PRO A O   1 
ATOM   4623 C  CB  . PRO A 1 629 ? 152.907 127.564 170.553 1.00 71.85  ? 629 PRO A CB  1 
ATOM   4624 C  CG  . PRO A 1 629 ? 152.834 128.529 171.661 1.00 71.85  ? 629 PRO A CG  1 
ATOM   4625 C  CD  . PRO A 1 629 ? 151.396 128.943 171.722 1.00 71.85  ? 629 PRO A CD  1 
ATOM   4626 N  N   . ALA A 1 630 ? 150.294 126.342 169.167 1.00 65.14  ? 630 ALA A N   1 
ATOM   4627 C  CA  . ALA A 1 630 ? 149.612 125.329 168.369 1.00 65.14  ? 630 ALA A CA  1 
ATOM   4628 C  C   . ALA A 1 630 ? 148.854 125.951 167.205 1.00 65.14  ? 630 ALA A C   1 
ATOM   4629 O  O   . ALA A 1 630 ? 148.723 125.328 166.146 1.00 65.14  ? 630 ALA A O   1 
ATOM   4630 C  CB  . ALA A 1 630 ? 148.664 124.515 169.247 1.00 65.14  ? 630 ALA A CB  1 
ATOM   4631 N  N   . LEU A 1 631 ? 148.348 127.172 167.384 1.00 65.72  ? 631 LEU A N   1 
ATOM   4632 C  CA  . LEU A 1 631 ? 147.644 127.850 166.302 1.00 65.72  ? 631 LEU A CA  1 
ATOM   4633 C  C   . LEU A 1 631 ? 148.615 128.340 165.235 1.00 65.72  ? 631 LEU A C   1 
ATOM   4634 O  O   . LEU A 1 631 ? 148.303 128.301 164.039 1.00 65.72  ? 631 LEU A O   1 
ATOM   4635 C  CB  . LEU A 1 631 ? 146.824 129.013 166.860 1.00 65.72  ? 631 LEU A CB  1 
ATOM   4636 C  CG  . LEU A 1 631 ? 145.390 128.766 167.340 1.00 65.72  ? 631 LEU A CG  1 
ATOM   4637 C  CD1 . LEU A 1 631 ? 144.507 128.374 166.182 1.00 65.72  ? 631 LEU A CD1 1 
ATOM   4638 C  CD2 . LEU A 1 631 ? 145.321 127.707 168.422 1.00 65.72  ? 631 LEU A CD2 1 
ATOM   4639 N  N   . LYS A 1 632 ? 149.793 128.816 165.651 1.00 69.73  ? 632 LYS A N   1 
ATOM   4640 C  CA  . LYS A 1 632 ? 150.778 129.316 164.697 1.00 69.73  ? 632 LYS A CA  1 
ATOM   4641 C  C   . LYS A 1 632 ? 151.310 128.200 163.807 1.00 69.73  ? 632 LYS A C   1 
ATOM   4642 O  O   . LYS A 1 632 ? 151.396 128.359 162.584 1.00 69.73  ? 632 LYS A O   1 
ATOM   4643 C  CB  . LYS A 1 632 ? 151.928 129.997 165.440 1.00 69.73  ? 632 LYS A CB  1 
ATOM   4644 C  CG  . LYS A 1 632 ? 151.949 131.511 165.314 1.00 69.73  ? 632 LYS A CG  1 
ATOM   4645 C  CD  . LYS A 1 632 ? 152.373 132.162 166.620 1.00 69.73  ? 632 LYS A CD  1 
ATOM   4646 C  CE  . LYS A 1 632 ? 153.810 131.815 166.971 1.00 69.73  ? 632 LYS A CE  1 
ATOM   4647 N  NZ  . LYS A 1 632 ? 154.251 132.477 168.229 1.00 69.73  ? 632 LYS A NZ  1 
ATOM   4648 N  N   . GLN A 1 633 ? 151.670 127.060 164.402 1.00 65.70  ? 633 GLN A N   1 
ATOM   4649 C  CA  . GLN A 1 633 ? 152.191 125.945 163.620 1.00 65.70  ? 633 GLN A CA  1 
ATOM   4650 C  C   . GLN A 1 633 ? 151.118 125.280 162.772 1.00 65.70  ? 633 GLN A C   1 
ATOM   4651 O  O   . GLN A 1 633 ? 151.453 124.589 161.804 1.00 65.70  ? 633 GLN A O   1 
ATOM   4652 C  CB  . GLN A 1 633 ? 152.843 124.914 164.541 1.00 65.70  ? 633 GLN A CB  1 
ATOM   4653 C  CG  . GLN A 1 633 ? 154.336 125.120 164.737 1.00 65.70  ? 633 GLN A CG  1 
ATOM   4654 C  CD  . GLN A 1 633 ? 154.655 126.340 165.578 1.00 65.70  ? 633 GLN A CD  1 
ATOM   4655 O  OE1 . GLN A 1 633 ? 154.602 126.293 166.807 1.00 65.70  ? 633 GLN A OE1 1 
ATOM   4656 N  NE2 . GLN A 1 633 ? 154.991 127.442 164.918 1.00 65.70  ? 633 GLN A NE2 1 
ATOM   4657 N  N   . ALA A 1 634 ? 149.846 125.466 163.112 1.00 66.03  ? 634 ALA A N   1 
ATOM   4658 C  CA  . ALA A 1 634 ? 148.768 124.942 162.287 1.00 66.03  ? 634 ALA A CA  1 
ATOM   4659 C  C   . ALA A 1 634 ? 148.698 125.699 160.969 1.00 66.03  ? 634 ALA A C   1 
ATOM   4660 O  O   . ALA A 1 634 ? 148.922 126.911 160.919 1.00 66.03  ? 634 ALA A O   1 
ATOM   4661 C  CB  . ALA A 1 634 ? 147.436 125.044 163.022 1.00 66.03  ? 634 ALA A CB  1 
ATOM   4662 N  N   . ASP A 1 635 ? 148.402 124.970 159.890 1.00 68.74  ? 635 ASP A N   1 
ATOM   4663 C  CA  . ASP A 1 635 ? 148.256 125.613 158.589 1.00 68.74  ? 635 ASP A CA  1 
ATOM   4664 C  C   . ASP A 1 635 ? 147.058 126.551 158.577 1.00 68.74  ? 635 ASP A C   1 
ATOM   4665 O  O   . ASP A 1 635 ? 147.176 127.724 158.204 1.00 68.74  ? 635 ASP A O   1 
ATOM   4666 C  CB  . ASP A 1 635 ? 148.118 124.558 157.491 1.00 68.74  ? 635 ASP A CB  1 
ATOM   4667 C  CG  . ASP A 1 635 ? 148.060 125.162 156.105 1.00 68.74  ? 635 ASP A CG  1 
ATOM   4668 O  OD1 . ASP A 1 635 ? 148.146 126.402 155.994 1.00 68.74  ? 635 ASP A OD1 1 
ATOM   4669 O  OD2 . ASP A 1 635 ? 147.929 124.398 155.125 1.00 68.74  ? 635 ASP A OD2 1 
ATOM   4670 N  N   . ILE A 1 636 ? 145.893 126.050 158.986 1.00 59.25  ? 636 ILE A N   1 
ATOM   4671 C  CA  . ILE A 1 636 ? 144.662 126.828 159.020 1.00 59.25  ? 636 ILE A CA  1 
ATOM   4672 C  C   . ILE A 1 636 ? 144.002 126.803 160.387 1.00 59.25  ? 636 ILE A C   1 
ATOM   4673 O  O   . ILE A 1 636 ? 142.776 126.668 160.465 1.00 59.25  ? 636 ILE A O   1 
ATOM   4674 C  CB  . ILE A 1 636 ? 143.660 126.359 157.946 1.00 59.25  ? 636 ILE A CB  1 
ATOM   4675 C  CG1 . ILE A 1 636 ? 144.193 126.635 156.546 1.00 59.25  ? 636 ILE A CG1 1 
ATOM   4676 C  CG2 . ILE A 1 636 ? 142.343 127.104 158.106 1.00 59.25  ? 636 ILE A CG2 1 
ATOM   4677 C  CD1 . ILE A 1 636 ? 143.402 125.980 155.480 1.00 59.25  ? 636 ILE A CD1 1 
ATOM   4678 N  N   . GLY A 1 637 ? 144.779 126.860 161.466 1.00 60.74  ? 637 GLY A N   1 
ATOM   4679 C  CA  . GLY A 1 637 ? 144.235 126.869 162.810 1.00 60.74  ? 637 GLY A CA  1 
ATOM   4680 C  C   . GLY A 1 637 ? 143.209 127.957 163.040 1.00 60.74  ? 637 GLY A C   1 
ATOM   4681 O  O   . GLY A 1 637 ? 143.444 129.121 162.701 1.00 60.74  ? 637 GLY A O   1 
ATOM   4682 N  N   . VAL A 1 638 ? 142.062 127.589 163.601 1.00 56.50  ? 638 VAL A N   1 
ATOM   4683 C  CA  . VAL A 1 638 ? 140.966 128.519 163.839 1.00 56.50  ? 638 VAL A CA  1 
ATOM   4684 C  C   . VAL A 1 638 ? 140.788 128.693 165.340 1.00 56.50  ? 638 VAL A C   1 
ATOM   4685 O  O   . VAL A 1 638 ? 140.744 127.709 166.086 1.00 56.50  ? 638 VAL A O   1 
ATOM   4686 C  CB  . VAL A 1 638 ? 139.663 128.047 163.167 1.00 56.50  ? 638 VAL A CB  1 
ATOM   4687 C  CG1 . VAL A 1 638 ? 138.489 128.947 163.512 1.00 56.50  ? 638 VAL A CG1 1 
ATOM   4688 C  CG2 . VAL A 1 638 ? 139.845 127.951 161.670 1.00 56.50  ? 638 VAL A CG2 1 
ATOM   4689 N  N   . ALA A 1 639 ? 140.718 129.943 165.785 1.00 58.58  ? 639 ALA A N   1 
ATOM   4690 C  CA  . ALA A 1 639 ? 140.414 130.256 167.171 1.00 58.58  ? 639 ALA A CA  1 
ATOM   4691 C  C   . ALA A 1 639 ? 138.937 130.589 167.318 1.00 58.58  ? 639 ALA A C   1 
ATOM   4692 O  O   . ALA A 1 639 ? 138.299 131.100 166.395 1.00 58.58  ? 639 ALA A O   1 
ATOM   4693 C  CB  . ALA A 1 639 ? 141.260 131.423 167.674 1.00 58.58  ? 639 ALA A CB  1 
ATOM   4694 N  N   . MET A 1 640 ? 138.398 130.283 168.491 1.00 61.18  ? 640 MET A N   1 
ATOM   4695 C  CA  . MET A 1 640 ? 136.993 130.524 168.770 1.00 61.18  ? 640 MET A CA  1 
ATOM   4696 C  C   . MET A 1 640 ? 136.731 132.005 169.011 1.00 61.18  ? 640 MET A C   1 
ATOM   4697 O  O   . MET A 1 640 ? 137.559 132.720 169.582 1.00 61.18  ? 640 MET A O   1 
ATOM   4698 C  CB  . MET A 1 640 ? 136.547 129.708 169.983 1.00 61.18  ? 640 MET A CB  1 
ATOM   4699 C  CG  . MET A 1 640 ? 136.830 128.194 169.954 1.00 61.18  ? 640 MET A CG  1 
ATOM   4700 S  SD  . MET A 1 640 ? 136.352 127.261 168.470 1.00 61.18  ? 640 MET A SD  1 
ATOM   4701 C  CE  . MET A 1 640 ? 137.788 127.306 167.400 1.00 61.18  ? 640 MET A CE  1 
ATOM   4702 N  N   . GLY A 1 641 ? 135.564 132.463 168.552 1.00 63.58  ? 641 GLY A N   1 
ATOM   4703 C  CA  . GLY A 1 641 ? 135.159 133.834 168.816 1.00 63.58  ? 641 GLY A CA  1 
ATOM   4704 C  C   . GLY A 1 641 ? 134.968 134.117 170.291 1.00 63.58  ? 641 GLY A C   1 
ATOM   4705 O  O   . GLY A 1 641 ? 135.262 135.219 170.760 1.00 63.58  ? 641 GLY A O   1 
ATOM   4706 N  N   . SER A 1 642 ? 134.477 133.131 171.042 1.00 66.39  ? 642 SER A N   1 
ATOM   4707 C  CA  . SER A 1 642 ? 134.396 133.239 172.492 1.00 66.39  ? 642 SER A CA  1 
ATOM   4708 C  C   . SER A 1 642 ? 135.748 133.071 173.171 1.00 66.39  ? 642 SER A C   1 
ATOM   4709 O  O   . SER A 1 642 ? 135.856 133.334 174.373 1.00 66.39  ? 642 SER A O   1 
ATOM   4710 C  CB  . SER A 1 642 ? 133.413 132.203 173.042 1.00 66.39  ? 642 SER A CB  1 
ATOM   4711 O  OG  . SER A 1 642 ? 133.898 130.886 172.847 1.00 66.39  ? 642 SER A OG  1 
ATOM   4712 N  N   . GLY A 1 643 ? 136.772 132.644 172.437 1.00 72.29  ? 643 GLY A N   1 
ATOM   4713 C  CA  . GLY A 1 643 ? 138.094 132.463 172.991 1.00 72.29  ? 643 GLY A CA  1 
ATOM   4714 C  C   . GLY A 1 643 ? 138.853 133.771 173.113 1.00 72.29  ? 643 GLY A C   1 
ATOM   4715 O  O   . GLY A 1 643 ? 138.343 134.860 172.842 1.00 72.29  ? 643 GLY A O   1 
ATOM   4716 N  N   . THR A 1 644 ? 140.107 133.647 173.536 1.00 80.32  ? 644 THR A N   1 
ATOM   4717 C  CA  . THR A 1 644 ? 140.946 134.815 173.758 1.00 80.32  ? 644 THR A CA  1 
ATOM   4718 C  C   . THR A 1 644 ? 141.371 135.442 172.434 1.00 80.32  ? 644 THR A C   1 
ATOM   4719 O  O   . THR A 1 644 ? 141.399 134.789 171.388 1.00 80.32  ? 644 THR A O   1 
ATOM   4720 C  CB  . THR A 1 644 ? 142.180 134.436 174.575 1.00 80.32  ? 644 THR A CB  1 
ATOM   4721 O  OG1 . THR A 1 644 ? 142.789 133.268 174.011 1.00 80.32  ? 644 THR A OG1 1 
ATOM   4722 C  CG2 . THR A 1 644 ? 141.788 134.149 176.014 1.00 80.32  ? 644 THR A CG2 1 
ATOM   4723 N  N   . ASP A 1 645 ? 141.705 136.734 172.494 1.00 88.60  ? 645 ASP A N   1 
ATOM   4724 C  CA  . ASP A 1 645 ? 142.086 137.461 171.287 1.00 88.60  ? 645 ASP A CA  1 
ATOM   4725 C  C   . ASP A 1 645 ? 143.474 137.068 170.799 1.00 88.60  ? 645 ASP A C   1 
ATOM   4726 O  O   . ASP A 1 645 ? 143.756 137.166 169.599 1.00 88.60  ? 645 ASP A O   1 
ATOM   4727 C  CB  . ASP A 1 645 ? 142.022 138.967 171.542 1.00 88.60  ? 645 ASP A CB  1 
ATOM   4728 C  CG  . ASP A 1 645 ? 140.666 139.414 172.053 1.00 88.60  ? 645 ASP A CG  1 
ATOM   4729 O  OD1 . ASP A 1 645 ? 140.268 138.971 173.150 1.00 88.60  ? 645 ASP A OD1 1 
ATOM   4730 O  OD2 . ASP A 1 645 ? 139.999 140.210 171.358 1.00 88.60  ? 645 ASP A OD2 1 
ATOM   4731 N  N   . VAL A 1 646 ? 144.354 136.637 171.706 1.00 87.09  ? 646 VAL A N   1 
ATOM   4732 C  CA  . VAL A 1 646 ? 145.700 136.249 171.298 1.00 87.09  ? 646 VAL A CA  1 
ATOM   4733 C  C   . VAL A 1 646 ? 145.665 134.970 170.467 1.00 87.09  ? 646 VAL A C   1 
ATOM   4734 O  O   . VAL A 1 646 ? 146.480 134.794 169.550 1.00 87.09  ? 646 VAL A O   1 
ATOM   4735 C  CB  . VAL A 1 646 ? 146.620 136.133 172.531 1.00 87.09  ? 646 VAL A CB  1 
ATOM   4736 C  CG1 . VAL A 1 646 ? 146.534 137.401 173.356 1.00 87.09  ? 646 VAL A CG1 1 
ATOM   4737 C  CG2 . VAL A 1 646 ? 146.260 134.934 173.395 1.00 87.09  ? 646 VAL A CG2 1 
ATOM   4738 N  N   . ALA A 1 647 ? 144.721 134.069 170.753 1.00 73.95  ? 647 ALA A N   1 
ATOM   4739 C  CA  . ALA A 1 647 ? 144.538 132.897 169.906 1.00 73.95  ? 647 ALA A CA  1 
ATOM   4740 C  C   . ALA A 1 647 ? 144.056 133.300 168.521 1.00 73.95  ? 647 ALA A C   1 
ATOM   4741 O  O   . ALA A 1 647 ? 144.485 132.721 167.517 1.00 73.95  ? 647 ALA A O   1 
ATOM   4742 C  CB  . ALA A 1 647 ? 143.560 131.922 170.560 1.00 73.95  ? 647 ALA A CB  1 
ATOM   4743 N  N   . LYS A 1 648 ? 143.163 134.294 168.450 1.00 67.99  ? 648 LYS A N   1 
ATOM   4744 C  CA  . LYS A 1 648 ? 142.705 134.803 167.161 1.00 67.99  ? 648 LYS A CA  1 
ATOM   4745 C  C   . LYS A 1 648 ? 143.851 135.427 166.378 1.00 67.99  ? 648 LYS A C   1 
ATOM   4746 O  O   . LYS A 1 648 ? 143.922 135.290 165.151 1.00 67.99  ? 648 LYS A O   1 
ATOM   4747 C  CB  . LYS A 1 648 ? 141.584 135.820 167.367 1.00 67.99  ? 648 LYS A CB  1 
ATOM   4748 C  CG  . LYS A 1 648 ? 140.449 135.333 168.250 1.00 67.99  ? 648 LYS A CG  1 
ATOM   4749 C  CD  . LYS A 1 648 ? 139.302 136.329 168.259 1.00 67.99  ? 648 LYS A CD  1 
ATOM   4750 C  CE  . LYS A 1 648 ? 138.231 135.932 169.259 1.00 67.99  ? 648 LYS A CE  1 
ATOM   4751 N  NZ  . LYS A 1 648 ? 136.991 136.738 169.090 1.00 67.99  ? 648 LYS A NZ  1 
ATOM   4752 N  N   . ASP A 1 649 ? 144.748 136.133 167.071 1.00 74.58  ? 649 ASP A N   1 
ATOM   4753 C  CA  . ASP A 1 649 ? 145.953 136.643 166.426 1.00 74.58  ? 649 ASP A CA  1 
ATOM   4754 C  C   . ASP A 1 649 ? 146.812 135.500 165.901 1.00 74.58  ? 649 ASP A C   1 
ATOM   4755 O  O   . ASP A 1 649 ? 147.357 135.578 164.794 1.00 74.58  ? 649 ASP A O   1 
ATOM   4756 C  CB  . ASP A 1 649 ? 146.747 137.508 167.405 1.00 74.58  ? 649 ASP A CB  1 
ATOM   4757 C  CG  . ASP A 1 649 ? 148.211 137.634 167.024 1.00 74.58  ? 649 ASP A CG  1 
ATOM   4758 O  OD1 . ASP A 1 649 ? 148.500 138.060 165.885 1.00 74.58  ? 649 ASP A OD1 1 
ATOM   4759 O  OD2 . ASP A 1 649 ? 149.074 137.301 167.862 1.00 74.58  ? 649 ASP A OD2 1 
ATOM   4760 N  N   . SER A 1 650 ? 146.939 134.426 166.682 1.00 69.59  ? 650 SER A N   1 
ATOM   4761 C  CA  . SER A 1 650 ? 147.680 133.254 166.234 1.00 69.59  ? 650 SER A CA  1 
ATOM   4762 C  C   . SER A 1 650 ? 146.908 132.406 165.231 1.00 69.59  ? 650 SER A C   1 
ATOM   4763 O  O   . SER A 1 650 ? 147.494 131.486 164.649 1.00 69.59  ? 650 SER A O   1 
ATOM   4764 C  CB  . SER A 1 650 ? 148.071 132.397 167.438 1.00 69.59  ? 650 SER A CB  1 
ATOM   4765 O  OG  . SER A 1 650 ? 149.174 131.563 167.133 1.00 69.59  ? 650 SER A OG  1 
ATOM   4766 N  N   . ALA A 1 651 ? 145.625 132.682 165.013 1.00 61.21  ? 651 ALA A N   1 
ATOM   4767 C  CA  . ALA A 1 651 ? 144.791 131.881 164.130 1.00 61.21  ? 651 ALA A CA  1 
ATOM   4768 C  C   . ALA A 1 651 ? 144.694 132.506 162.745 1.00 61.21  ? 651 ALA A C   1 
ATOM   4769 O  O   . ALA A 1 651 ? 144.759 133.727 162.585 1.00 61.21  ? 651 ALA A O   1 
ATOM   4770 C  CB  . ALA A 1 651 ? 143.384 131.712 164.702 1.00 61.21  ? 651 ALA A CB  1 
ATOM   4771 N  N   . ALA A 1 652 ? 144.536 131.645 161.741 1.00 57.54  ? 652 ALA A N   1 
ATOM   4772 C  CA  . ALA A 1 652 ? 144.283 132.105 160.384 1.00 57.54  ? 652 ALA A CA  1 
ATOM   4773 C  C   . ALA A 1 652 ? 142.839 132.537 160.170 1.00 57.54  ? 652 ALA A C   1 
ATOM   4774 O  O   . ALA A 1 652 ? 142.569 133.304 159.239 1.00 57.54  ? 652 ALA A O   1 
ATOM   4775 C  CB  . ALA A 1 652 ? 144.645 131.008 159.380 1.00 57.54  ? 652 ALA A CB  1 
ATOM   4776 N  N   . MET A 1 653 ? 141.914 132.070 161.005 1.00 58.15  ? 653 MET A N   1 
ATOM   4777 C  CA  . MET A 1 653 ? 140.496 132.340 160.817 1.00 58.15  ? 653 MET A CA  1 
ATOM   4778 C  C   . MET A 1 653 ? 139.783 132.169 162.153 1.00 58.15  ? 653 MET A C   1 
ATOM   4779 O  O   . MET A 1 653 ? 140.317 131.563 163.084 1.00 58.15  ? 653 MET A O   1 
ATOM   4780 C  CB  . MET A 1 653 ? 139.910 131.429 159.732 1.00 58.15  ? 653 MET A CB  1 
ATOM   4781 C  CG  . MET A 1 653 ? 139.556 130.037 160.195 1.00 58.15  ? 653 MET A CG  1 
ATOM   4782 S  SD  . MET A 1 653 ? 138.509 129.161 159.023 1.00 58.15  ? 653 MET A SD  1 
ATOM   4783 C  CE  . MET A 1 653 ? 137.067 130.214 159.031 1.00 58.15  ? 653 MET A CE  1 
ATOM   4784 N  N   . ILE A 1 654 ? 138.586 132.750 162.250 1.00 62.09  ? 654 ILE A N   1 
ATOM   4785 C  CA  . ILE A 1 654 ? 137.803 132.774 163.484 1.00 62.09  ? 654 ILE A CA  1 
ATOM   4786 C  C   . ILE A 1 654 ? 136.370 132.366 163.168 1.00 62.09  ? 654 ILE A C   1 
ATOM   4787 O  O   . ILE A 1 654 ? 135.830 132.734 162.119 1.00 62.09  ? 654 ILE A O   1 
ATOM   4788 C  CB  . ILE A 1 654 ? 137.818 134.170 164.153 1.00 62.09  ? 654 ILE A CB  1 
ATOM   4789 C  CG1 . ILE A 1 654 ? 139.224 134.773 164.179 1.00 62.09  ? 654 ILE A CG1 1 
ATOM   4790 C  CG2 . ILE A 1 654 ? 137.256 134.108 165.567 1.00 62.09  ? 654 ILE A CG2 1 
ATOM   4791 C  CD1 . ILE A 1 654 ? 139.242 136.256 164.472 1.00 62.09  ? 654 ILE A CD1 1 
ATOM   4792 N  N   . LEU A 1 655 ? 135.753 131.605 164.071 1.00 54.45  ? 655 LEU A N   1 
ATOM   4793 C  CA  . LEU A 1 655 ? 134.317 131.348 164.033 1.00 54.45  ? 655 LEU A CA  1 
ATOM   4794 C  C   . LEU A 1 655 ? 133.635 132.228 165.073 1.00 54.45  ? 655 LEU A C   1 
ATOM   4795 O  O   . LEU A 1 655 ? 133.976 132.168 166.259 1.00 54.45  ? 655 LEU A O   1 
ATOM   4796 C  CB  . LEU A 1 655 ? 133.996 129.880 164.308 1.00 54.45  ? 655 LEU A CB  1 
ATOM   4797 C  CG  . LEU A 1 655 ? 134.926 128.794 163.777 1.00 54.45  ? 655 LEU A CG  1 
ATOM   4798 C  CD1 . LEU A 1 655 ? 134.633 127.474 164.466 1.00 54.45  ? 655 LEU A CD1 1 
ATOM   4799 C  CD2 . LEU A 1 655 ? 134.800 128.658 162.270 1.00 54.45  ? 655 LEU A CD2 1 
ATOM   4800 N  N   . THR A 1 656 ? 132.675 133.041 164.630 1.00 59.03  ? 656 THR A N   1 
ATOM   4801 C  CA  . THR A 1 656 ? 131.922 133.865 165.571 1.00 59.03  ? 656 THR A CA  1 
ATOM   4802 C  C   . THR A 1 656 ? 130.945 133.025 166.383 1.00 59.03  ? 656 THR A C   1 
ATOM   4803 O  O   . THR A 1 656 ? 130.843 133.181 167.605 1.00 59.03  ? 656 THR A O   1 
ATOM   4804 C  CB  . THR A 1 656 ? 131.182 134.976 164.829 1.00 59.03  ? 656 THR A CB  1 
ATOM   4805 O  OG1 . THR A 1 656 ? 130.432 134.414 163.745 1.00 59.03  ? 656 THR A OG1 1 
ATOM   4806 C  CG2 . THR A 1 656 ? 132.164 135.993 164.295 1.00 59.03  ? 656 THR A CG2 1 
ATOM   4807 N  N   . ASP A 1 657 ? 130.217 132.125 165.722 1.00 58.82  ? 657 ASP A N   1 
ATOM   4808 C  CA  . ASP A 1 657 ? 129.240 131.297 166.416 1.00 58.82  ? 657 ASP A CA  1 
ATOM   4809 C  C   . ASP A 1 657 ? 129.868 130.109 167.129 1.00 58.82  ? 657 ASP A C   1 
ATOM   4810 O  O   . ASP A 1 657 ? 129.141 129.364 167.796 1.00 58.82  ? 657 ASP A O   1 
ATOM   4811 C  CB  . ASP A 1 657 ? 128.171 130.803 165.439 1.00 58.82  ? 657 ASP A CB  1 
ATOM   4812 C  CG  . ASP A 1 657 ? 126.773 130.867 166.023 1.00 58.82  ? 657 ASP A CG  1 
ATOM   4813 O  OD1 . ASP A 1 657 ? 126.639 130.765 167.261 1.00 58.82  ? 657 ASP A OD1 1 
ATOM   4814 O  OD2 . ASP A 1 657 ? 125.808 131.019 165.246 1.00 58.82  ? 657 ASP A OD2 1 
ATOM   4815 N  N   . ASP A 1 658 ? 131.173 129.878 166.937 1.00 56.63  ? 658 ASP A N   1 
ATOM   4816 C  CA  . ASP A 1 658 ? 131.995 128.986 167.755 1.00 56.63  ? 658 ASP A CA  1 
ATOM   4817 C  C   . ASP A 1 658 ? 131.675 127.511 167.488 1.00 56.63  ? 658 ASP A C   1 
ATOM   4818 O  O   . ASP A 1 658 ? 132.408 126.619 167.925 1.00 56.63  ? 658 ASP A O   1 
ATOM   4819 C  CB  . ASP A 1 658 ? 131.832 129.384 169.238 1.00 56.63  ? 658 ASP A CB  1 
ATOM   4820 C  CG  . ASP A 1 658 ? 132.421 128.380 170.207 1.00 56.63  ? 658 ASP A CG  1 
ATOM   4821 O  OD1 . ASP A 1 658 ? 133.619 128.060 170.085 1.00 56.63  ? 658 ASP A OD1 1 
ATOM   4822 O  OD2 . ASP A 1 658 ? 131.682 127.922 171.102 1.00 56.63  ? 658 ASP A OD2 1 
ATOM   4823 N  N   . ASN A 1 659 ? 130.643 127.243 166.691 1.00 52.38  ? 659 ASN A N   1 
ATOM   4824 C  CA  . ASN A 1 659 ? 130.201 125.875 166.460 1.00 52.38  ? 659 ASN A CA  1 
ATOM   4825 C  C   . ASN A 1 659 ? 131.135 125.142 165.502 1.00 52.38  ? 659 ASN A C   1 
ATOM   4826 O  O   . ASN A 1 659 ? 131.797 125.747 164.655 1.00 52.38  ? 659 ASN A O   1 
ATOM   4827 C  CB  . ASN A 1 659 ? 128.778 125.863 165.904 1.00 52.38  ? 659 ASN A CB  1 
ATOM   4828 C  CG  . ASN A 1 659 ? 128.524 126.996 164.931 1.00 52.38  ? 659 ASN A CG  1 
ATOM   4829 O  OD1 . ASN A 1 659 ? 129.387 127.844 164.710 1.00 52.38  ? 659 ASN A OD1 1 
ATOM   4830 N  ND2 . ASN A 1 659 ? 127.333 127.016 164.345 1.00 52.38  ? 659 ASN A ND2 1 
ATOM   4831 N  N   . PHE A 1 660 ? 131.183 123.815 165.651 1.00 47.39  ? 660 PHE A N   1 
ATOM   4832 C  CA  . PHE A 1 660 ? 131.979 122.988 164.750 1.00 47.39  ? 660 PHE A CA  1 
ATOM   4833 C  C   . PHE A 1 660 ? 131.382 122.948 163.350 1.00 47.39  ? 660 PHE A C   1 
ATOM   4834 O  O   . PHE A 1 660 ? 132.117 122.776 162.370 1.00 47.39  ? 660 PHE A O   1 
ATOM   4835 C  CB  . PHE A 1 660 ? 132.108 121.573 165.313 1.00 47.39  ? 660 PHE A CB  1 
ATOM   4836 C  CG  . PHE A 1 660 ? 132.604 120.563 164.319 1.00 47.39  ? 660 PHE A CG  1 
ATOM   4837 C  CD1 . PHE A 1 660 ? 133.924 120.572 163.904 1.00 47.39  ? 660 PHE A CD1 1 
ATOM   4838 C  CD2 . PHE A 1 660 ? 131.751 119.607 163.799 1.00 47.39  ? 660 PHE A CD2 1 
ATOM   4839 C  CE1 . PHE A 1 660 ? 134.381 119.645 162.989 1.00 47.39  ? 660 PHE A CE1 1 
ATOM   4840 C  CE2 . PHE A 1 660 ? 132.204 118.681 162.884 1.00 47.39  ? 660 PHE A CE2 1 
ATOM   4841 C  CZ  . PHE A 1 660 ? 133.523 118.697 162.483 1.00 47.39  ? 660 PHE A CZ  1 
ATOM   4842 N  N   . VAL A 1 661 ? 130.060 123.108 163.237 1.00 49.56  ? 661 VAL A N   1 
ATOM   4843 C  CA  . VAL A 1 661 ? 129.408 123.121 161.929 1.00 49.56  ? 661 VAL A CA  1 
ATOM   4844 C  C   . VAL A 1 661 ? 129.919 124.280 161.086 1.00 49.56  ? 661 VAL A C   1 
ATOM   4845 O  O   . VAL A 1 661 ? 129.922 124.209 159.850 1.00 49.56  ? 661 VAL A O   1 
ATOM   4846 C  CB  . VAL A 1 661 ? 127.877 123.178 162.098 1.00 49.56  ? 661 VAL A CB  1 
ATOM   4847 C  CG1 . VAL A 1 661 ? 127.184 122.666 160.845 1.00 49.56  ? 661 VAL A CG1 1 
ATOM   4848 C  CG2 . VAL A 1 661 ? 127.446 122.380 163.320 1.00 49.56  ? 661 VAL A CG2 1 
ATOM   4849 N  N   . SER A 1 662 ? 130.369 125.357 161.735 1.00 51.86  ? 662 SER A N   1 
ATOM   4850 C  CA  . SER A 1 662 ? 130.994 126.454 161.008 1.00 51.86  ? 662 SER A CA  1 
ATOM   4851 C  C   . SER A 1 662 ? 132.297 126.021 160.349 1.00 51.86  ? 662 SER A C   1 
ATOM   4852 O  O   . SER A 1 662 ? 132.621 126.506 159.265 1.00 51.86  ? 662 SER A O   1 
ATOM   4853 C  CB  . SER A 1 662 ? 131.234 127.636 161.944 1.00 51.86  ? 662 SER A CB  1 
ATOM   4854 O  OG  . SER A 1 662 ? 130.013 128.270 162.284 1.00 51.86  ? 662 SER A OG  1 
ATOM   4855 N  N   . ILE A 1 663 ? 133.041 125.097 160.964 1.00 45.16  ? 663 ILE A N   1 
ATOM   4856 C  CA  . ILE A 1 663 ? 134.278 124.614 160.351 1.00 45.16  ? 663 ILE A CA  1 
ATOM   4857 C  C   . ILE A 1 663 ? 133.981 123.809 159.088 1.00 45.16  ? 663 ILE A C   1 
ATOM   4858 O  O   . ILE A 1 663 ? 134.646 123.977 158.057 1.00 45.16  ? 663 ILE A O   1 
ATOM   4859 C  CB  . ILE A 1 663 ? 135.095 123.799 161.372 1.00 45.16  ? 663 ILE A CB  1 
ATOM   4860 C  CG1 . ILE A 1 663 ? 135.824 124.736 162.335 1.00 45.16  ? 663 ILE A CG1 1 
ATOM   4861 C  CG2 . ILE A 1 663 ? 136.100 122.889 160.677 1.00 45.16  ? 663 ILE A CG2 1 
ATOM   4862 C  CD1 . ILE A 1 663 ? 136.594 124.022 163.422 1.00 45.16  ? 663 ILE A CD1 1 
ATOM   4863 N  N   . VAL A 1 664 ? 132.980 122.926 159.144 1.00 48.10  ? 664 VAL A N   1 
ATOM   4864 C  CA  . VAL A 1 664 ? 132.642 122.115 157.977 1.00 48.10  ? 664 VAL A CA  1 
ATOM   4865 C  C   . VAL A 1 664 ? 132.052 122.986 156.875 1.00 48.10  ? 664 VAL A C   1 
ATOM   4866 O  O   . VAL A 1 664 ? 132.346 122.797 155.688 1.00 48.10  ? 664 VAL A O   1 
ATOM   4867 C  CB  . VAL A 1 664 ? 131.685 120.978 158.376 1.00 48.10  ? 664 VAL A CB  1 
ATOM   4868 C  CG1 . VAL A 1 664 ? 131.489 120.017 157.217 1.00 48.10  ? 664 VAL A CG1 1 
ATOM   4869 C  CG2 . VAL A 1 664 ? 132.211 120.251 159.594 1.00 48.10  ? 664 VAL A CG2 1 
ATOM   4870 N  N   . ASP A 1 665 ? 131.226 123.967 157.248 1.00 54.57  ? 665 ASP A N   1 
ATOM   4871 C  CA  . ASP A 1 665 ? 130.726 124.918 156.261 1.00 54.57  ? 665 ASP A CA  1 
ATOM   4872 C  C   . ASP A 1 665 ? 131.863 125.743 155.671 1.00 54.57  ? 665 ASP A C   1 
ATOM   4873 O  O   . ASP A 1 665 ? 131.847 126.076 154.481 1.00 54.57  ? 665 ASP A O   1 
ATOM   4874 C  CB  . ASP A 1 665 ? 129.668 125.819 156.895 1.00 54.57  ? 665 ASP A CB  1 
ATOM   4875 C  CG  . ASP A 1 665 ? 128.382 125.077 157.191 1.00 54.57  ? 665 ASP A CG  1 
ATOM   4876 O  OD1 . ASP A 1 665 ? 128.140 124.041 156.537 1.00 54.57  ? 665 ASP A OD1 1 
ATOM   4877 O  OD2 . ASP A 1 665 ? 127.614 125.523 158.070 1.00 54.57  ? 665 ASP A OD2 1 
ATOM   4878 N  N   . ALA A 1 666 ? 132.874 126.054 156.484 1.00 48.56  ? 666 ALA A N   1 
ATOM   4879 C  CA  . ALA A 1 666 ? 134.022 126.815 156.011 1.00 48.56  ? 666 ALA A CA  1 
ATOM   4880 C  C   . ALA A 1 666 ? 134.837 126.025 154.996 1.00 48.56  ? 666 ALA A C   1 
ATOM   4881 O  O   . ALA A 1 666 ? 135.232 126.563 153.953 1.00 48.56  ? 666 ALA A O   1 
ATOM   4882 C  CB  . ALA A 1 666 ? 134.890 127.214 157.204 1.00 48.56  ? 666 ALA A CB  1 
ATOM   4883 N  N   . VAL A 1 667 ? 135.097 124.747 155.278 1.00 42.82  ? 667 VAL A N   1 
ATOM   4884 C  CA  . VAL A 1 667 ? 135.873 123.950 154.332 1.00 42.82  ? 667 VAL A CA  1 
ATOM   4885 C  C   . VAL A 1 667 ? 135.047 123.645 153.086 1.00 42.82  ? 667 VAL A C   1 
ATOM   4886 O  O   . VAL A 1 667 ? 135.600 123.522 151.985 1.00 42.82  ? 667 VAL A O   1 
ATOM   4887 C  CB  . VAL A 1 667 ? 136.426 122.675 155.002 1.00 42.82  ? 667 VAL A CB  1 
ATOM   4888 C  CG1 . VAL A 1 667 ? 137.277 123.047 156.208 1.00 42.82  ? 667 VAL A CG1 1 
ATOM   4889 C  CG2 . VAL A 1 667 ? 135.323 121.717 155.395 1.00 42.82  ? 667 VAL A CG2 1 
ATOM   4890 N  N   . GLY A 1 668 ? 133.721 123.555 153.219 1.00 42.60  ? 668 GLY A N   1 
ATOM   4891 C  CA  . GLY A 1 668 ? 132.878 123.443 152.040 1.00 42.60  ? 668 GLY A CA  1 
ATOM   4892 C  C   . GLY A 1 668 ? 132.924 124.686 151.171 1.00 42.60  ? 668 GLY A C   1 
ATOM   4893 O  O   . GLY A 1 668 ? 132.961 124.593 149.942 1.00 42.60  ? 668 GLY A O   1 
ATOM   4894 N  N   . VAL A 1 669 ? 132.934 125.866 151.797 1.00 42.17  ? 669 VAL A N   1 
ATOM   4895 C  CA  . VAL A 1 669 ? 133.054 127.113 151.046 1.00 42.17  ? 669 VAL A CA  1 
ATOM   4896 C  C   . VAL A 1 669 ? 134.421 127.205 150.374 1.00 42.17  ? 669 VAL A C   1 
ATOM   4897 O  O   . VAL A 1 669 ? 134.537 127.679 149.238 1.00 42.17  ? 669 VAL A O   1 
ATOM   4898 C  CB  . VAL A 1 669 ? 132.779 128.314 151.972 1.00 42.17  ? 669 VAL A CB  1 
ATOM   4899 C  CG1 . VAL A 1 669 ? 133.247 129.621 151.345 1.00 42.17  ? 669 VAL A CG1 1 
ATOM   4900 C  CG2 . VAL A 1 669 ? 131.296 128.397 152.289 1.00 42.17  ? 669 VAL A CG2 1 
ATOM   4901 N  N   . GLY A 1 670 ? 135.472 126.740 151.052 1.00 45.48  ? 670 GLY A N   1 
ATOM   4902 C  CA  . GLY A 1 670 ? 136.788 126.711 150.428 1.00 45.48  ? 670 GLY A CA  1 
ATOM   4903 C  C   . GLY A 1 670 ? 136.855 125.773 149.236 1.00 45.48  ? 670 GLY A C   1 
ATOM   4904 O  O   . GLY A 1 670 ? 137.454 126.102 148.204 1.00 45.48  ? 670 GLY A O   1 
ATOM   4905 N  N   . ARG A 1 671 ? 136.235 124.594 149.358 1.00 46.19  ? 671 ARG A N   1 
ATOM   4906 C  CA  . ARG A 1 671 ? 136.143 123.677 148.227 1.00 46.19  ? 671 ARG A CA  1 
ATOM   4907 C  C   . ARG A 1 671 ? 135.352 124.295 147.082 1.00 46.19  ? 671 ARG A C   1 
ATOM   4908 O  O   . ARG A 1 671 ? 135.714 124.137 145.913 1.00 46.19  ? 671 ARG A O   1 
ATOM   4909 C  CB  . ARG A 1 671 ? 135.499 122.362 148.664 1.00 46.19  ? 671 ARG A CB  1 
ATOM   4910 C  CG  . ARG A 1 671 ? 136.443 121.394 149.347 1.00 46.19  ? 671 ARG A CG  1 
ATOM   4911 C  CD  . ARG A 1 671 ? 135.801 120.030 149.503 1.00 46.19  ? 671 ARG A CD  1 
ATOM   4912 N  NE  . ARG A 1 671 ? 136.554 119.167 150.404 1.00 46.19  ? 671 ARG A NE  1 
ATOM   4913 C  CZ  . ARG A 1 671 ? 136.315 117.875 150.571 1.00 46.19  ? 671 ARG A CZ  1 
ATOM   4914 N  NH1 . ARG A 1 671 ? 135.351 117.259 149.906 1.00 46.19  ? 671 ARG A NH1 1 
ATOM   4915 N  NH2 . ARG A 1 671 ? 137.061 117.182 151.425 1.00 46.19  ? 671 ARG A NH2 1 
ATOM   4916 N  N   . THR A 1 672 ? 134.266 125.000 147.405 1.00 42.01  ? 672 THR A N   1 
ATOM   4917 C  CA  . THR A 1 672 ? 133.464 125.665 146.383 1.00 42.01  ? 672 THR A CA  1 
ATOM   4918 C  C   . THR A 1 672 ? 134.265 126.759 145.682 1.00 42.01  ? 672 THR A C   1 
ATOM   4919 O  O   . THR A 1 672 ? 134.175 126.919 144.461 1.00 42.01  ? 672 THR A O   1 
ATOM   4920 C  CB  . THR A 1 672 ? 132.189 126.225 147.024 1.00 42.01  ? 672 THR A CB  1 
ATOM   4921 O  OG1 . THR A 1 672 ? 131.228 125.171 147.169 1.00 42.01  ? 672 THR A OG1 1 
ATOM   4922 C  CG2 . THR A 1 672 ? 131.574 127.340 146.191 1.00 42.01  ? 672 THR A CG2 1 
ATOM   4923 N  N   . VAL A 1 673 ? 135.084 127.495 146.436 1.00 43.45  ? 673 VAL A N   1 
ATOM   4924 C  CA  . VAL A 1 673 ? 135.908 128.551 145.853 1.00 43.45  ? 673 VAL A CA  1 
ATOM   4925 C  C   . VAL A 1 673 ? 136.965 127.961 144.922 1.00 43.45  ? 673 VAL A C   1 
ATOM   4926 O  O   . VAL A 1 673 ? 137.193 128.469 143.814 1.00 43.45  ? 673 VAL A O   1 
ATOM   4927 C  CB  . VAL A 1 673 ? 136.533 129.404 146.974 1.00 43.45  ? 673 VAL A CB  1 
ATOM   4928 C  CG1 . VAL A 1 673 ? 137.851 130.028 146.531 1.00 43.45  ? 673 VAL A CG1 1 
ATOM   4929 C  CG2 . VAL A 1 673 ? 135.555 130.478 147.426 1.00 43.45  ? 673 VAL A CG2 1 
ATOM   4930 N  N   . PHE A 1 674 ? 137.621 126.875 145.344 1.00 49.63  ? 674 PHE A N   1 
ATOM   4931 C  CA  . PHE A 1 674 ? 138.614 126.261 144.466 1.00 49.63  ? 674 PHE A CA  1 
ATOM   4932 C  C   . PHE A 1 674 ? 137.968 125.609 143.249 1.00 49.63  ? 674 PHE A C   1 
ATOM   4933 O  O   . PHE A 1 674 ? 138.549 125.623 142.156 1.00 49.63  ? 674 PHE A O   1 
ATOM   4934 C  CB  . PHE A 1 674 ? 139.458 125.245 145.229 1.00 49.63  ? 674 PHE A CB  1 
ATOM   4935 C  CG  . PHE A 1 674 ? 140.892 125.226 144.797 1.00 49.63  ? 674 PHE A CG  1 
ATOM   4936 C  CD1 . PHE A 1 674 ? 141.800 126.122 145.333 1.00 49.63  ? 674 PHE A CD1 1 
ATOM   4937 C  CD2 . PHE A 1 674 ? 141.327 124.332 143.833 1.00 49.63  ? 674 PHE A CD2 1 
ATOM   4938 C  CE1 . PHE A 1 674 ? 143.118 126.118 144.929 1.00 49.63  ? 674 PHE A CE1 1 
ATOM   4939 C  CE2 . PHE A 1 674 ? 142.646 124.322 143.424 1.00 49.63  ? 674 PHE A CE2 1 
ATOM   4940 C  CZ  . PHE A 1 674 ? 143.543 125.216 143.974 1.00 49.63  ? 674 PHE A CZ  1 
ATOM   4941 N  N   . ASP A 1 675 ? 136.767 125.050 143.405 1.00 46.22  ? 675 ASP A N   1 
ATOM   4942 C  CA  . ASP A 1 675 ? 136.040 124.536 142.252 1.00 46.22  ? 675 ASP A CA  1 
ATOM   4943 C  C   . ASP A 1 675 ? 135.617 125.660 141.317 1.00 46.22  ? 675 ASP A C   1 
ATOM   4944 O  O   . ASP A 1 675 ? 135.540 125.455 140.104 1.00 46.22  ? 675 ASP A O   1 
ATOM   4945 C  CB  . ASP A 1 675 ? 134.826 123.731 142.710 1.00 46.22  ? 675 ASP A CB  1 
ATOM   4946 C  CG  . ASP A 1 675 ? 135.111 122.246 142.791 1.00 46.22  ? 675 ASP A CG  1 
ATOM   4947 O  OD1 . ASP A 1 675 ? 135.899 121.747 141.961 1.00 46.22  ? 675 ASP A OD1 1 
ATOM   4948 O  OD2 . ASP A 1 675 ? 134.555 121.577 143.687 1.00 46.22  ? 675 ASP A OD2 1 
ATOM   4949 N  N   . ASN A 1 676 ? 135.339 126.848 141.859 1.00 41.19  ? 676 ASN A N   1 
ATOM   4950 C  CA  . ASN A 1 676 ? 135.050 128.000 141.012 1.00 41.19  ? 676 ASN A CA  1 
ATOM   4951 C  C   . ASN A 1 676 ? 136.285 128.433 140.234 1.00 41.19  ? 676 ASN A C   1 
ATOM   4952 O  O   . ASN A 1 676 ? 136.183 128.789 139.056 1.00 41.19  ? 676 ASN A O   1 
ATOM   4953 C  CB  . ASN A 1 676 ? 134.509 129.152 141.853 1.00 41.19  ? 676 ASN A CB  1 
ATOM   4954 C  CG  . ASN A 1 676 ? 133.025 129.027 142.114 1.00 41.19  ? 676 ASN A CG  1 
ATOM   4955 O  OD1 . ASN A 1 676 ? 132.204 129.288 141.235 1.00 41.19  ? 676 ASN A OD1 1 
ATOM   4956 N  ND2 . ASN A 1 676 ? 132.671 128.632 143.328 1.00 41.19  ? 676 ASN A ND2 1 
ATOM   4957 N  N   . ILE A 1 677 ? 137.456 128.414 140.881 1.00 41.17  ? 677 ILE A N   1 
ATOM   4958 C  CA  . ILE A 1 677 ? 138.719 128.595 140.161 1.00 41.17  ? 677 ILE A CA  1 
ATOM   4959 C  C   . ILE A 1 677 ? 138.835 127.600 139.017 1.00 41.17  ? 677 ILE A C   1 
ATOM   4960 O  O   . ILE A 1 677 ? 139.099 127.976 137.867 1.00 41.17  ? 677 ILE A O   1 
ATOM   4961 C  CB  . ILE A 1 677 ? 139.917 128.468 141.122 1.00 41.17  ? 677 ILE A CB  1 
ATOM   4962 C  CG1 . ILE A 1 677 ? 139.905 129.560 142.176 1.00 41.17  ? 677 ILE A CG1 1 
ATOM   4963 C  CG2 . ILE A 1 677 ? 141.215 128.538 140.359 1.00 41.17  ? 677 ILE A CG2 1 
ATOM   4964 C  CD1 . ILE A 1 677 ? 139.649 130.888 141.564 1.00 41.17  ? 677 ILE A CD1 1 
ATOM   4965 N  N   . LYS A 1 678 ? 138.615 126.319 139.315 1.00 40.69  ? 678 LYS A N   1 
ATOM   4966 C  CA  . LYS A 1 678 ? 138.794 125.280 138.307 1.00 40.69  ? 678 LYS A CA  1 
ATOM   4967 C  C   . LYS A 1 678 ? 137.816 125.457 137.152 1.00 40.69  ? 678 LYS A C   1 
ATOM   4968 O  O   . LYS A 1 678 ? 138.213 125.407 135.985 1.00 40.69  ? 678 LYS A O   1 
ATOM   4969 C  CB  . LYS A 1 678 ? 138.638 123.905 138.951 1.00 40.69  ? 678 LYS A CB  1 
ATOM   4970 C  CG  . LYS A 1 678 ? 139.961 123.274 139.347 1.00 40.69  ? 678 LYS A CG  1 
ATOM   4971 C  CD  . LYS A 1 678 ? 139.783 121.854 139.848 1.00 40.69  ? 678 LYS A CD  1 
ATOM   4972 C  CE  . LYS A 1 678 ? 141.127 121.222 140.164 1.00 40.69  ? 678 LYS A CE  1 
ATOM   4973 N  NZ  . LYS A 1 678 ? 140.987 119.941 140.910 1.00 40.69  ? 678 LYS A NZ  1 
ATOM   4974 N  N   . LYS A 1 679 ? 136.549 125.737 137.461 1.00 38.52  ? 679 LYS A N   1 
ATOM   4975 C  CA  . LYS A 1 679 ? 135.528 125.872 136.427 1.00 38.52  ? 679 LYS A CA  1 
ATOM   4976 C  C   . LYS A 1 679 ? 135.728 127.134 135.595 1.00 38.52  ? 679 LYS A C   1 
ATOM   4977 O  O   . LYS A 1 679 ? 135.565 127.102 134.371 1.00 38.52  ? 679 LYS A O   1 
ATOM   4978 C  CB  . LYS A 1 679 ? 134.140 125.861 137.066 1.00 38.52  ? 679 LYS A CB  1 
ATOM   4979 C  CG  . LYS A 1 679 ? 133.510 124.477 137.143 1.00 38.52  ? 679 LYS A CG  1 
ATOM   4980 C  CD  . LYS A 1 679 ? 132.906 124.193 138.514 1.00 38.52  ? 679 LYS A CD  1 
ATOM   4981 C  CE  . LYS A 1 679 ? 132.179 125.400 139.086 1.00 38.52  ? 679 LYS A CE  1 
ATOM   4982 N  NZ  . LYS A 1 679 ? 131.595 125.102 140.422 1.00 38.52  ? 679 LYS A NZ  1 
ATOM   4983 N  N   . SER A 1 680 ? 136.085 128.254 136.230 1.00 36.94  ? 680 SER A N   1 
ATOM   4984 C  CA  . SER A 1 680 ? 136.258 129.496 135.485 1.00 36.94  ? 680 SER A CA  1 
ATOM   4985 C  C   . SER A 1 680 ? 137.494 129.444 134.595 1.00 36.94  ? 680 SER A C   1 
ATOM   4986 O  O   . SER A 1 680 ? 137.444 129.864 133.430 1.00 36.94  ? 680 SER A O   1 
ATOM   4987 C  CB  . SER A 1 680 ? 136.332 130.676 136.452 1.00 36.94  ? 680 SER A CB  1 
ATOM   4988 O  OG  . SER A 1 680 ? 135.913 131.871 135.819 1.00 36.94  ? 680 SER A OG  1 
ATOM   4989 N  N   . ILE A 1 681 ? 138.614 128.930 135.119 1.00 40.57  ? 681 ILE A N   1 
ATOM   4990 C  CA  . ILE A 1 681 ? 139.802 128.763 134.287 1.00 40.57  ? 681 ILE A CA  1 
ATOM   4991 C  C   . ILE A 1 681 ? 139.536 127.743 133.188 1.00 40.57  ? 681 ILE A C   1 
ATOM   4992 O  O   . ILE A 1 681 ? 140.015 127.891 132.059 1.00 40.57  ? 681 ILE A O   1 
ATOM   4993 C  CB  . ILE A 1 681 ? 141.019 128.376 135.149 1.00 40.57  ? 681 ILE A CB  1 
ATOM   4994 C  CG1 . ILE A 1 681 ? 141.354 129.495 136.132 1.00 40.57  ? 681 ILE A CG1 1 
ATOM   4995 C  CG2 . ILE A 1 681 ? 142.239 128.084 134.287 1.00 40.57  ? 681 ILE A CG2 1 
ATOM   4996 C  CD1 . ILE A 1 681 ? 142.520 129.165 137.032 1.00 40.57  ? 681 ILE A CD1 1 
ATOM   4997 N  N   . ALA A 1 682 ? 138.743 126.709 133.489 1.00 37.99  ? 682 ALA A N   1 
ATOM   4998 C  CA  . ALA A 1 682 ? 138.382 125.731 132.472 1.00 37.99  ? 682 ALA A CA  1 
ATOM   4999 C  C   . ALA A 1 682 ? 137.588 126.374 131.347 1.00 37.99  ? 682 ALA A C   1 
ATOM   5000 O  O   . ALA A 1 682 ? 137.876 126.142 130.172 1.00 37.99  ? 682 ALA A O   1 
ATOM   5001 C  CB  . ALA A 1 682 ? 137.587 124.589 133.103 1.00 37.99  ? 682 ALA A CB  1 
ATOM   5002 N  N   . TYR A 1 683 ? 136.614 127.217 131.692 1.00 34.30  ? 683 TYR A N   1 
ATOM   5003 C  CA  . TYR A 1 683 ? 135.813 127.902 130.682 1.00 34.30  ? 683 TYR A CA  1 
ATOM   5004 C  C   . TYR A 1 683 ? 136.677 128.825 129.831 1.00 34.30  ? 683 TYR A C   1 
ATOM   5005 O  O   . TYR A 1 683 ? 136.610 128.792 128.594 1.00 34.30  ? 683 TYR A O   1 
ATOM   5006 C  CB  . TYR A 1 683 ? 134.691 128.679 131.373 1.00 34.30  ? 683 TYR A CB  1 
ATOM   5007 C  CG  . TYR A 1 683 ? 134.104 129.838 130.595 1.00 34.30  ? 683 TYR A CG  1 
ATOM   5008 C  CD1 . TYR A 1 683 ? 133.497 129.645 129.361 1.00 34.30  ? 683 TYR A CD1 1 
ATOM   5009 C  CD2 . TYR A 1 683 ? 134.143 131.127 131.110 1.00 34.30  ? 683 TYR A CD2 1 
ATOM   5010 C  CE1 . TYR A 1 683 ? 132.956 130.706 128.659 1.00 34.30  ? 683 TYR A CE1 1 
ATOM   5011 C  CE2 . TYR A 1 683 ? 133.605 132.192 130.415 1.00 34.30  ? 683 TYR A CE2 1 
ATOM   5012 C  CZ  . TYR A 1 683 ? 133.012 131.976 129.190 1.00 34.30  ? 683 TYR A CZ  1 
ATOM   5013 O  OH  . TYR A 1 683 ? 132.475 133.035 128.496 1.00 34.30  ? 683 TYR A OH  1 
ATOM   5014 N  N   . LEU A 1 684 ? 137.526 129.627 130.480 1.00 36.13  ? 684 LEU A N   1 
ATOM   5015 C  CA  . LEU A 1 684 ? 138.351 130.582 129.745 1.00 36.13  ? 684 LEU A CA  1 
ATOM   5016 C  C   . LEU A 1 684 ? 139.347 129.875 128.835 1.00 36.13  ? 684 LEU A C   1 
ATOM   5017 O  O   . LEU A 1 684 ? 139.417 130.162 127.633 1.00 36.13  ? 684 LEU A O   1 
ATOM   5018 C  CB  . LEU A 1 684 ? 139.076 131.508 130.720 1.00 36.13  ? 684 LEU A CB  1 
ATOM   5019 C  CG  . LEU A 1 684 ? 138.226 132.631 131.309 1.00 36.13  ? 684 LEU A CG  1 
ATOM   5020 C  CD1 . LEU A 1 684 ? 139.106 133.767 131.800 1.00 36.13  ? 684 LEU A CD1 1 
ATOM   5021 C  CD2 . LEU A 1 684 ? 137.226 133.122 130.277 1.00 36.13  ? 684 LEU A CD2 1 
ATOM   5022 N  N   . PHE A 1 685 ? 140.117 128.936 129.390 1.00 39.07  ? 685 PHE A N   1 
ATOM   5023 C  CA  . PHE A 1 685 ? 141.121 128.234 128.604 1.00 39.07  ? 685 PHE A CA  1 
ATOM   5024 C  C   . PHE A 1 685 ? 140.482 127.359 127.536 1.00 39.07  ? 685 PHE A C   1 
ATOM   5025 O  O   . PHE A 1 685 ? 141.043 127.219 126.449 1.00 39.07  ? 685 PHE A O   1 
ATOM   5026 C  CB  . PHE A 1 685 ? 142.013 127.397 129.521 1.00 39.07  ? 685 PHE A CB  1 
ATOM   5027 C  CG  . PHE A 1 685 ? 143.231 126.839 128.840 1.00 39.07  ? 685 PHE A CG  1 
ATOM   5028 C  CD1 . PHE A 1 685 ? 143.869 127.549 127.835 1.00 39.07  ? 685 PHE A CD1 1 
ATOM   5029 C  CD2 . PHE A 1 685 ? 143.740 125.603 129.205 1.00 39.07  ? 685 PHE A CD2 1 
ATOM   5030 C  CE1 . PHE A 1 685 ? 144.989 127.037 127.207 1.00 39.07  ? 685 PHE A CE1 1 
ATOM   5031 C  CE2 . PHE A 1 685 ? 144.860 125.086 128.581 1.00 39.07  ? 685 PHE A CE2 1 
ATOM   5032 C  CZ  . PHE A 1 685 ? 145.485 125.804 127.581 1.00 39.07  ? 685 PHE A CZ  1 
ATOM   5033 N  N   . ALA A 1 686 ? 139.301 126.797 127.803 1.00 40.28  ? 686 ALA A N   1 
ATOM   5034 C  CA  . ALA A 1 686 ? 138.629 125.973 126.808 1.00 40.28  ? 686 ALA A CA  1 
ATOM   5035 C  C   . ALA A 1 686 ? 138.144 126.806 125.633 1.00 40.28  ? 686 ALA A C   1 
ATOM   5036 O  O   . ALA A 1 686 ? 138.317 126.408 124.477 1.00 40.28  ? 686 ALA A O   1 
ATOM   5037 C  CB  . ALA A 1 686 ? 137.465 125.232 127.455 1.00 40.28  ? 686 ALA A CB  1 
ATOM   5038 N  N   . GLY A 1 687 ? 137.534 127.962 125.901 1.00 35.80  ? 687 GLY A N   1 
ATOM   5039 C  CA  . GLY A 1 687 ? 137.127 128.826 124.806 1.00 35.80  ? 687 GLY A CA  1 
ATOM   5040 C  C   . GLY A 1 687 ? 138.305 129.360 124.015 1.00 35.80  ? 687 GLY A C   1 
ATOM   5041 O  O   . GLY A 1 687 ? 138.273 129.402 122.777 1.00 35.80  ? 687 GLY A O   1 
ATOM   5042 N  N   . ASN A 1 688 ? 139.368 129.763 124.717 1.00 35.54  ? 688 ASN A N   1 
ATOM   5043 C  CA  . ASN A 1 688 ? 140.558 130.258 124.037 1.00 35.54  ? 688 ASN A CA  1 
ATOM   5044 C  C   . ASN A 1 688 ? 141.204 129.164 123.199 1.00 35.54  ? 688 ASN A C   1 
ATOM   5045 O  O   . ASN A 1 688 ? 141.655 129.417 122.078 1.00 35.54  ? 688 ASN A O   1 
ATOM   5046 C  CB  . ASN A 1 688 ? 141.544 130.813 125.060 1.00 35.54  ? 688 ASN A CB  1 
ATOM   5047 C  CG  . ASN A 1 688 ? 140.988 132.003 125.809 1.00 35.54  ? 688 ASN A CG  1 
ATOM   5048 O  OD1 . ASN A 1 688 ? 139.843 132.403 125.598 1.00 35.54  ? 688 ASN A OD1 1 
ATOM   5049 N  ND2 . ASN A 1 688 ? 141.799 132.584 126.685 1.00 35.54  ? 688 ASN A ND2 1 
ATOM   5050 N  N   . LEU A 1 689 ? 141.230 127.932 123.714 1.00 37.25  ? 689 LEU A N   1 
ATOM   5051 C  CA  . LEU A 1 689 ? 141.781 126.815 122.961 1.00 37.25  ? 689 LEU A CA  1 
ATOM   5052 C  C   . LEU A 1 689 ? 140.903 126.449 121.775 1.00 37.25  ? 689 LEU A C   1 
ATOM   5053 O  O   . LEU A 1 689 ? 141.422 126.041 120.734 1.00 37.25  ? 689 LEU A O   1 
ATOM   5054 C  CB  . LEU A 1 689 ? 141.964 125.608 123.879 1.00 37.25  ? 689 LEU A CB  1 
ATOM   5055 C  CG  . LEU A 1 689 ? 142.947 124.539 123.405 1.00 37.25  ? 689 LEU A CG  1 
ATOM   5056 C  CD1 . LEU A 1 689 ? 143.888 124.153 124.534 1.00 37.25  ? 689 LEU A CD1 1 
ATOM   5057 C  CD2 . LEU A 1 689 ? 142.205 123.321 122.881 1.00 37.25  ? 689 LEU A CD2 1 
ATOM   5058 N  N   . GLY A 1 690 ? 139.582 126.578 121.909 1.00 57.46  ? 690 GLY A N   1 
ATOM   5059 C  CA  . GLY A 1 690 ? 138.713 126.354 120.766 1.00 57.46  ? 690 GLY A CA  1 
ATOM   5060 C  C   . GLY A 1 690 ? 138.975 127.347 119.653 1.00 57.46  ? 690 GLY A C   1 
ATOM   5061 O  O   . GLY A 1 690 ? 139.090 126.973 118.481 1.00 57.46  ? 690 GLY A O   1 
ATOM   5062 N  N   . ALA A 1 691 ? 139.108 128.627 120.014 1.00 30.65  ? 691 ALA A N   1 
ATOM   5063 C  CA  . ALA A 1 691 ? 139.477 129.639 119.027 1.00 30.65  ? 691 ALA A CA  1 
ATOM   5064 C  C   . ALA A 1 691 ? 140.847 129.349 118.421 1.00 30.65  ? 691 ALA A C   1 
ATOM   5065 O  O   . ALA A 1 691 ? 141.041 129.495 117.206 1.00 30.65  ? 691 ALA A O   1 
ATOM   5066 C  CB  . ALA A 1 691 ? 139.457 131.026 119.667 1.00 30.65  ? 691 ALA A CB  1 
ATOM   5067 N  N   . ILE A 1 692 ? 141.801 128.919 119.253 1.00 27.35  ? 692 ILE A N   1 
ATOM   5068 C  CA  . ILE A 1 692 ? 143.160 128.653 118.788 1.00 27.35  ? 692 ILE A CA  1 
ATOM   5069 C  C   . ILE A 1 692 ? 143.169 127.512 117.779 1.00 27.35  ? 692 ILE A C   1 
ATOM   5070 O  O   . ILE A 1 692 ? 143.789 127.611 116.714 1.00 27.35  ? 692 ILE A O   1 
ATOM   5071 C  CB  . ILE A 1 692 ? 144.084 128.357 119.983 1.00 27.35  ? 692 ILE A CB  1 
ATOM   5072 C  CG1 . ILE A 1 692 ? 144.544 129.655 120.643 1.00 27.35  ? 692 ILE A CG1 1 
ATOM   5073 C  CG2 . ILE A 1 692 ? 145.293 127.531 119.559 1.00 27.35  ? 692 ILE A CG2 1 
ATOM   5074 C  CD1 . ILE A 1 692 ? 145.093 129.450 122.033 1.00 27.35  ? 692 ILE A CD1 1 
ATOM   5075 N  N   . ILE A 1 693 ? 142.480 126.411 118.092 1.00 30.46  ? 693 ILE A N   1 
ATOM   5076 C  CA  . ILE A 1 693 ? 142.473 125.282 117.168 1.00 30.46  ? 693 ILE A CA  1 
ATOM   5077 C  C   . ILE A 1 693 ? 141.646 125.591 115.927 1.00 30.46  ? 693 ILE A C   1 
ATOM   5078 O  O   . ILE A 1 693 ? 141.937 125.066 114.850 1.00 30.46  ? 693 ILE A O   1 
ATOM   5079 C  CB  . ILE A 1 693 ? 142.013 123.981 117.860 1.00 30.46  ? 693 ILE A CB  1 
ATOM   5080 C  CG1 . ILE A 1 693 ? 140.497 123.957 118.078 1.00 30.46  ? 693 ILE A CG1 1 
ATOM   5081 C  CG2 . ILE A 1 693 ? 142.816 123.718 119.131 1.00 30.46  ? 693 ILE A CG2 1 
ATOM   5082 C  CD1 . ILE A 1 693 ? 139.882 122.592 117.872 1.00 30.46  ? 693 ILE A CD1 1 
ATOM   5083 N  N   . ALA A 1 694 ? 140.639 126.465 116.031 1.00 30.13  ? 694 ALA A N   1 
ATOM   5084 C  CA  . ALA A 1 694 ? 139.933 126.905 114.830 1.00 30.13  ? 694 ALA A CA  1 
ATOM   5085 C  C   . ALA A 1 694 ? 140.866 127.669 113.898 1.00 30.13  ? 694 ALA A C   1 
ATOM   5086 O  O   . ALA A 1 694 ? 140.916 127.403 112.688 1.00 30.13  ? 694 ALA A O   1 
ATOM   5087 C  CB  . ALA A 1 694 ? 138.732 127.765 115.216 1.00 30.13  ? 694 ALA A CB  1 
ATOM   5088 N  N   . ILE A 1 695 ? 141.634 128.609 114.457 1.00 30.39  ? 695 ILE A N   1 
ATOM   5089 C  CA  . ILE A 1 695 ? 142.584 129.377 113.654 1.00 30.39  ? 695 ILE A CA  1 
ATOM   5090 C  C   . ILE A 1 695 ? 143.660 128.465 113.075 1.00 30.39  ? 695 ILE A C   1 
ATOM   5091 O  O   . ILE A 1 695 ? 144.036 128.591 111.904 1.00 30.39  ? 695 ILE A O   1 
ATOM   5092 C  CB  . ILE A 1 695 ? 143.187 130.524 114.490 1.00 30.39  ? 695 ILE A CB  1 
ATOM   5093 C  CG1 . ILE A 1 695 ? 142.114 131.565 114.809 1.00 30.39  ? 695 ILE A CG1 1 
ATOM   5094 C  CG2 . ILE A 1 695 ? 144.344 131.183 113.762 1.00 30.39  ? 695 ILE A CG2 1 
ATOM   5095 C  CD1 . ILE A 1 695 ? 142.296 132.249 116.141 1.00 30.39  ? 695 ILE A CD1 1 
ATOM   5096 N  N   . LEU A 1 696 ? 144.147 127.509 113.869 1.00 32.79  ? 696 LEU A N   1 
ATOM   5097 C  CA  . LEU A 1 696 ? 145.205 126.621 113.395 1.00 32.79  ? 696 LEU A CA  1 
ATOM   5098 C  C   . LEU A 1 696 ? 144.698 125.662 112.322 1.00 32.79  ? 696 LEU A C   1 
ATOM   5099 O  O   . LEU A 1 696 ? 145.440 125.311 111.397 1.00 32.79  ? 696 LEU A O   1 
ATOM   5100 C  CB  . LEU A 1 696 ? 145.807 125.848 114.568 1.00 32.79  ? 696 LEU A CB  1 
ATOM   5101 C  CG  . LEU A 1 696 ? 146.681 126.638 115.548 1.00 32.79  ? 696 LEU A CG  1 
ATOM   5102 C  CD1 . LEU A 1 696 ? 147.598 125.705 116.323 1.00 32.79  ? 696 LEU A CD1 1 
ATOM   5103 C  CD2 . LEU A 1 696 ? 147.489 127.711 114.831 1.00 32.79  ? 696 LEU A CD2 1 
ATOM   5104 N  N   . PHE A 1 697 ? 143.442 125.220 112.426 1.00 37.30  ? 697 PHE A N   1 
ATOM   5105 C  CA  . PHE A 1 697 ? 142.881 124.349 111.401 1.00 37.30  ? 697 PHE A CA  1 
ATOM   5106 C  C   . PHE A 1 697 ? 142.615 125.118 110.116 1.00 37.30  ? 697 PHE A C   1 
ATOM   5107 O  O   . PHE A 1 697 ? 142.769 124.565 109.021 1.00 37.30  ? 697 PHE A O   1 
ATOM   5108 C  CB  . PHE A 1 697 ? 141.607 123.689 111.931 1.00 37.30  ? 697 PHE A CB  1 
ATOM   5109 C  CG  . PHE A 1 697 ? 141.248 122.392 111.249 1.00 37.30  ? 697 PHE A CG  1 
ATOM   5110 C  CD1 . PHE A 1 697 ? 140.801 122.365 109.937 1.00 37.30  ? 697 PHE A CD1 1 
ATOM   5111 C  CD2 . PHE A 1 697 ? 141.374 121.190 111.929 1.00 37.30  ? 697 PHE A CD2 1 
ATOM   5112 C  CE1 . PHE A 1 697 ? 140.477 121.170 109.323 1.00 37.30  ? 697 PHE A CE1 1 
ATOM   5113 C  CE2 . PHE A 1 697 ? 141.052 119.992 111.319 1.00 37.30  ? 697 PHE A CE2 1 
ATOM   5114 C  CZ  . PHE A 1 697 ? 140.603 119.982 110.014 1.00 37.30  ? 697 PHE A CZ  1 
ATOM   5115 N  N   . ALA A 1 698 ? 142.223 126.390 110.222 1.00 39.61  ? 698 ALA A N   1 
ATOM   5116 C  CA  . ALA A 1 698 ? 142.185 127.230 109.029 1.00 39.61  ? 698 ALA A CA  1 
ATOM   5117 C  C   . ALA A 1 698 ? 143.582 127.442 108.458 1.00 39.61  ? 698 ALA A C   1 
ATOM   5118 O  O   . ALA A 1 698 ? 143.743 127.586 107.242 1.00 39.61  ? 698 ALA A O   1 
ATOM   5119 C  CB  . ALA A 1 698 ? 141.529 128.572 109.346 1.00 39.61  ? 698 ALA A CB  1 
ATOM   5120 N  N   . LEU A 1 699 ? 144.599 127.466 109.322 1.00 39.60  ? 699 LEU A N   1 
ATOM   5121 C  CA  . LEU A 1 699 ? 145.970 127.664 108.863 1.00 39.60  ? 699 LEU A CA  1 
ATOM   5122 C  C   . LEU A 1 699 ? 146.485 126.454 108.093 1.00 39.60  ? 699 LEU A C   1 
ATOM   5123 O  O   . LEU A 1 699 ? 147.120 126.605 107.043 1.00 39.60  ? 699 LEU A O   1 
ATOM   5124 C  CB  . LEU A 1 699 ? 146.880 127.956 110.056 1.00 39.60  ? 699 LEU A CB  1 
ATOM   5125 C  CG  . LEU A 1 699 ? 147.394 129.386 110.212 1.00 39.60  ? 699 LEU A CG  1 
ATOM   5126 C  CD1 . LEU A 1 699 ? 146.237 130.368 110.165 1.00 39.60  ? 699 LEU A CD1 1 
ATOM   5127 C  CD2 . LEU A 1 699 ? 148.180 129.534 111.504 1.00 39.60  ? 699 LEU A CD2 1 
ATOM   5128 N  N   . VAL A 1 700 ? 146.230 125.246 108.602 1.00 42.55  ? 700 VAL A N   1 
ATOM   5129 C  CA  . VAL A 1 700 ? 146.814 124.051 107.997 1.00 42.55  ? 700 VAL A CA  1 
ATOM   5130 C  C   . VAL A 1 700 ? 146.163 123.737 106.651 1.00 42.55  ? 700 VAL A C   1 
ATOM   5131 O  O   . VAL A 1 700 ? 146.825 123.222 105.741 1.00 42.55  ? 700 VAL A O   1 
ATOM   5132 C  CB  . VAL A 1 700 ? 146.736 122.860 108.978 1.00 42.55  ? 700 VAL A CB  1 
ATOM   5133 C  CG1 . VAL A 1 700 ? 145.295 122.494 109.304 1.00 42.55  ? 700 VAL A CG1 1 
ATOM   5134 C  CG2 . VAL A 1 700 ? 147.499 121.653 108.441 1.00 42.55  ? 700 VAL A CG2 1 
ATOM   5135 N  N   . LEU A 1 701 ? 144.881 124.061 106.482 1.00 43.13  ? 701 LEU A N   1 
ATOM   5136 C  CA  . LEU A 1 701 ? 144.147 123.710 105.275 1.00 43.13  ? 701 LEU A CA  1 
ATOM   5137 C  C   . LEU A 1 701 ? 144.159 124.818 104.227 1.00 43.13  ? 701 LEU A C   1 
ATOM   5138 O  O   . LEU A 1 701 ? 143.335 124.782 103.304 1.00 43.13  ? 701 LEU A O   1 
ATOM   5139 C  CB  . LEU A 1 701 ? 142.704 123.336 105.623 1.00 43.13  ? 701 LEU A CB  1 
ATOM   5140 C  CG  . LEU A 1 701 ? 142.372 121.843 105.655 1.00 43.13  ? 701 LEU A CG  1 
ATOM   5141 C  CD1 . LEU A 1 701 ? 140.870 121.632 105.739 1.00 43.13  ? 701 LEU A CD1 1 
ATOM   5142 C  CD2 . LEU A 1 701 ? 142.945 121.133 104.437 1.00 43.13  ? 701 LEU A CD2 1 
ATOM   5143 N  N   . ASP A 1 702 ? 145.076 125.785 104.348 1.00 50.50  ? 702 ASP A N   1 
ATOM   5144 C  CA  . ASP A 1 702 ? 145.210 126.904 103.408 1.00 50.50  ? 702 ASP A CA  1 
ATOM   5145 C  C   . ASP A 1 702 ? 143.893 127.669 103.277 1.00 50.50  ? 702 ASP A C   1 
ATOM   5146 O  O   . ASP A 1 702 ? 143.370 127.879 102.180 1.00 50.50  ? 702 ASP A O   1 
ATOM   5147 C  CB  . ASP A 1 702 ? 145.716 126.424 102.043 1.00 50.50  ? 702 ASP A CB  1 
ATOM   5148 C  CG  . ASP A 1 702 ? 146.274 127.552 101.193 1.00 50.50  ? 702 ASP A CG  1 
ATOM   5149 O  OD1 . ASP A 1 702 ? 146.348 128.696 101.688 1.00 50.50  ? 702 ASP A OD1 1 
ATOM   5150 O  OD2 . ASP A 1 702 ? 146.641 127.292 100.028 1.00 50.50  ? 702 ASP A OD2 1 
ATOM   5151 N  N   . TRP A 1 703 ? 143.352 128.078 104.418 1.00 40.57  ? 703 TRP A N   1 
ATOM   5152 C  CA  . TRP A 1 703 ? 142.049 128.715 104.492 1.00 40.57  ? 703 TRP A CA  1 
ATOM   5153 C  C   . TRP A 1 703 ? 142.193 130.139 105.008 1.00 40.57  ? 703 TRP A C   1 
ATOM   5154 O  O   . TRP A 1 703 ? 143.177 130.489 105.665 1.00 40.57  ? 703 TRP A O   1 
ATOM   5155 C  CB  . TRP A 1 703 ? 141.106 127.933 105.412 1.00 40.57  ? 703 TRP A CB  1 
ATOM   5156 C  CG  . TRP A 1 703 ? 140.177 127.011 104.702 1.00 40.57  ? 703 TRP A CG  1 
ATOM   5157 C  CD1 . TRP A 1 703 ? 140.110 126.782 103.360 1.00 40.57  ? 703 TRP A CD1 1 
ATOM   5158 C  CD2 . TRP A 1 703 ? 139.191 126.166 105.304 1.00 40.57  ? 703 TRP A CD2 1 
ATOM   5159 N  NE1 . TRP A 1 703 ? 139.132 125.856 103.087 1.00 40.57  ? 703 TRP A NE1 1 
ATOM   5160 C  CE2 . TRP A 1 703 ? 138.555 125.462 104.265 1.00 40.57  ? 703 TRP A CE2 1 
ATOM   5161 C  CE3 . TRP A 1 703 ? 138.781 125.942 106.621 1.00 40.57  ? 703 TRP A CE3 1 
ATOM   5162 C  CZ2 . TRP A 1 703 ? 137.532 124.549 104.503 1.00 40.57  ? 703 TRP A CZ2 1 
ATOM   5163 C  CZ3 . TRP A 1 703 ? 137.766 125.037 106.854 1.00 40.57  ? 703 TRP A CZ3 1 
ATOM   5164 C  CH2 . TRP A 1 703 ? 137.154 124.351 105.801 1.00 40.57  ? 703 TRP A CH2 1 
ATOM   5165 N  N   . ILE A 1 704 ? 141.195 130.964 104.687 1.00 35.84  ? 704 ILE A N   1 
ATOM   5166 C  CA  . ILE A 1 704 ? 141.095 132.273 105.314 1.00 35.84  ? 704 ILE A CA  1 
ATOM   5167 C  C   . ILE A 1 704 ? 140.835 132.077 106.801 1.00 35.84  ? 704 ILE A C   1 
ATOM   5168 O  O   . ILE A 1 704 ? 140.030 131.225 107.202 1.00 35.84  ? 704 ILE A O   1 
ATOM   5169 C  CB  . ILE A 1 704 ? 139.995 133.109 104.637 1.00 35.84  ? 704 ILE A CB  1 
ATOM   5170 C  CG1 . ILE A 1 704 ? 139.674 134.363 105.455 1.00 35.84  ? 704 ILE A CG1 1 
ATOM   5171 C  CG2 . ILE A 1 704 ? 138.743 132.271 104.413 1.00 35.84  ? 704 ILE A CG2 1 
ATOM   5172 C  CD1 . ILE A 1 704 ? 139.148 135.514 104.627 1.00 35.84  ? 704 ILE A CD1 1 
ATOM   5173 N  N   . ASN A 1 705 ? 141.553 132.836 107.624 1.00 37.81  ? 705 ASN A N   1 
ATOM   5174 C  CA  . ASN A 1 705 ? 141.469 132.674 109.069 1.00 37.81  ? 705 ASN A CA  1 
ATOM   5175 C  C   . ASN A 1 705 ? 140.050 132.965 109.554 1.00 37.81  ? 705 ASN A C   1 
ATOM   5176 O  O   . ASN A 1 705 ? 139.398 133.881 109.042 1.00 37.81  ? 705 ASN A O   1 
ATOM   5177 C  CB  . ASN A 1 705 ? 142.469 133.598 109.760 1.00 37.81  ? 705 ASN A CB  1 
ATOM   5178 C  CG  . ASN A 1 705 ? 142.616 134.920 109.050 1.00 37.81  ? 705 ASN A CG  1 
ATOM   5179 O  OD1 . ASN A 1 705 ? 141.768 135.308 108.248 1.00 37.81  ? 705 ASN A OD1 1 
ATOM   5180 N  ND2 . ASN A 1 705 ? 143.707 135.611 109.325 1.00 37.81  ? 705 ASN A ND2 1 
ATOM   5181 N  N   . PRO A 1 706 ? 139.539 132.193 110.518 1.00 32.28  ? 706 PRO A N   1 
ATOM   5182 C  CA  . PRO A 1 706 ? 138.110 132.286 110.863 1.00 32.28  ? 706 PRO A CA  1 
ATOM   5183 C  C   . PRO A 1 706 ? 137.691 133.638 111.405 1.00 32.28  ? 706 PRO A C   1 
ATOM   5184 O  O   . PRO A 1 706 ? 136.550 134.059 111.177 1.00 32.28  ? 706 PRO A O   1 
ATOM   5185 C  CB  . PRO A 1 706 ? 137.930 131.183 111.919 1.00 32.28  ? 706 PRO A CB  1 
ATOM   5186 C  CG  . PRO A 1 706 ? 139.194 130.373 111.891 1.00 32.28  ? 706 PRO A CG  1 
ATOM   5187 C  CD  . PRO A 1 706 ? 140.263 131.294 111.428 1.00 32.28  ? 706 PRO A CD  1 
ATOM   5188 N  N   . PHE A 1 707 ? 138.594 134.303 112.128 1.00 32.91  ? 707 PHE A N   1 
ATOM   5189 C  CA  . PHE A 1 707 ? 138.206 135.584 112.770 1.00 32.91  ? 707 PHE A CA  1 
ATOM   5190 C  C   . PHE A 1 707 ? 139.227 136.677 112.463 1.00 32.91  ? 707 PHE A C   1 
ATOM   5191 O  O   . PHE A 1 707 ? 140.440 136.418 112.598 1.00 32.91  ? 707 PHE A O   1 
ATOM   5192 C  CB  . PHE A 1 707 ? 138.058 135.420 114.286 1.00 32.91  ? 707 PHE A CB  1 
ATOM   5193 C  CG  . PHE A 1 707 ? 137.774 134.013 114.745 1.00 32.91  ? 707 PHE A CG  1 
ATOM   5194 C  CD1 . PHE A 1 707 ? 136.492 133.492 114.682 1.00 32.91  ? 707 PHE A CD1 1 
ATOM   5195 C  CD2 . PHE A 1 707 ? 138.789 133.210 115.238 1.00 32.91  ? 707 PHE A CD2 1 
ATOM   5196 C  CE1 . PHE A 1 707 ? 136.235 132.196 115.098 1.00 32.91  ? 707 PHE A CE1 1 
ATOM   5197 C  CE2 . PHE A 1 707 ? 138.530 131.915 115.656 1.00 32.91  ? 707 PHE A CE2 1 
ATOM   5198 C  CZ  . PHE A 1 707 ? 137.253 131.411 115.584 1.00 32.91  ? 707 PHE A CZ  1 
ATOM   5199 N  N   . THR A 1 708 ? 138.750 137.855 112.059 1.00 35.14  ? 708 THR A N   1 
ATOM   5200 C  CA  . THR A 1 708 ? 139.625 138.995 111.851 1.00 35.14  ? 708 THR A CA  1 
ATOM   5201 C  C   . THR A 1 708 ? 140.135 139.499 113.200 1.00 35.14  ? 708 THR A C   1 
ATOM   5202 O  O   . THR A 1 708 ? 139.861 138.919 114.255 1.00 35.14  ? 708 THR A O   1 
ATOM   5203 C  CB  . THR A 1 708 ? 138.900 140.096 111.079 1.00 35.14  ? 708 THR A CB  1 
ATOM   5204 O  OG1 . THR A 1 708 ? 139.834 141.120 110.713 1.00 35.14  ? 708 THR A OG1 1 
ATOM   5205 C  CG2 . THR A 1 708 ? 137.793 140.706 111.921 1.00 35.14  ? 708 THR A CG2 1 
ATOM   5206 N  N   . ALA A 1 709 ? 140.905 140.588 113.167 1.00 41.67  ? 709 ALA A N   1 
ATOM   5207 C  CA  . ALA A 1 709 ? 141.424 141.159 114.405 1.00 41.67  ? 709 ALA A CA  1 
ATOM   5208 C  C   . ALA A 1 709 ? 140.294 141.657 115.295 1.00 41.67  ? 709 ALA A C   1 
ATOM   5209 O  O   . ALA A 1 709 ? 140.217 141.303 116.477 1.00 41.67  ? 709 ALA A O   1 
ATOM   5210 C  CB  . ALA A 1 709 ? 142.397 142.293 114.092 1.00 41.67  ? 709 ALA A CB  1 
ATOM   5211 N  N   . LEU A 1 710 ? 139.387 142.460 114.732 1.00 47.00  ? 710 LEU A N   1 
ATOM   5212 C  CA  . LEU A 1 710 ? 138.309 143.032 115.530 1.00 47.00  ? 710 LEU A CA  1 
ATOM   5213 C  C   . LEU A 1 710 ? 137.340 141.966 116.023 1.00 47.00  ? 710 LEU A C   1 
ATOM   5214 O  O   . LEU A 1 710 ? 136.804 142.092 117.127 1.00 47.00  ? 710 LEU A O   1 
ATOM   5215 C  CB  . LEU A 1 710 ? 137.564 144.099 114.730 1.00 47.00  ? 710 LEU A CB  1 
ATOM   5216 C  CG  . LEU A 1 710 ? 136.598 144.964 115.544 1.00 47.00  ? 710 LEU A CG  1 
ATOM   5217 C  CD1 . LEU A 1 710 ? 137.269 145.470 116.811 1.00 47.00  ? 710 LEU A CD1 1 
ATOM   5218 C  CD2 . LEU A 1 710 ? 136.084 146.125 114.716 1.00 47.00  ? 710 LEU A CD2 1 
ATOM   5219 N  N   . GLN A 1 711 ? 137.110 140.911 115.236 1.00 39.25  ? 711 GLN A N   1 
ATOM   5220 C  CA  . GLN A 1 711 ? 136.240 139.831 115.692 1.00 39.25  ? 711 GLN A CA  1 
ATOM   5221 C  C   . GLN A 1 711 ? 136.835 139.109 116.894 1.00 39.25  ? 711 GLN A C   1 
ATOM   5222 O  O   . GLN A 1 711 ? 136.130 138.833 117.872 1.00 39.25  ? 711 GLN A O   1 
ATOM   5223 C  CB  . GLN A 1 711 ? 135.982 138.843 114.556 1.00 39.25  ? 711 GLN A CB  1 
ATOM   5224 C  CG  . GLN A 1 711 ? 134.853 139.239 113.625 1.00 39.25  ? 711 GLN A CG  1 
ATOM   5225 C  CD  . GLN A 1 711 ? 134.876 138.453 112.332 1.00 39.25  ? 711 GLN A CD  1 
ATOM   5226 O  OE1 . GLN A 1 711 ? 135.664 137.523 112.176 1.00 39.25  ? 711 GLN A OE1 1 
ATOM   5227 N  NE2 . GLN A 1 711 ? 134.005 138.816 111.401 1.00 39.25  ? 711 GLN A NE2 1 
ATOM   5228 N  N   . LEU A 1 712 ? 138.133 138.801 116.844 1.00 35.16  ? 712 LEU A N   1 
ATOM   5229 C  CA  . LEU A 1 712 ? 138.781 138.134 117.969 1.00 35.16  ? 712 LEU A CA  1 
ATOM   5230 C  C   . LEU A 1 712 ? 138.826 139.036 119.195 1.00 35.16  ? 712 LEU A C   1 
ATOM   5231 O  O   . LEU A 1 712 ? 138.627 138.570 120.324 1.00 35.16  ? 712 LEU A O   1 
ATOM   5232 C  CB  . LEU A 1 712 ? 140.189 137.690 117.580 1.00 35.16  ? 712 LEU A CB  1 
ATOM   5233 C  CG  . LEU A 1 712 ? 140.365 136.205 117.267 1.00 35.16  ? 712 LEU A CG  1 
ATOM   5234 C  CD1 . LEU A 1 712 ? 141.805 135.912 116.886 1.00 35.16  ? 712 LEU A CD1 1 
ATOM   5235 C  CD2 . LEU A 1 712 ? 139.934 135.354 118.447 1.00 35.16  ? 712 LEU A CD2 1 
ATOM   5236 N  N   . LEU A 1 713 ? 139.079 140.331 118.995 1.00 42.04  ? 713 LEU A N   1 
ATOM   5237 C  CA  . LEU A 1 713 ? 139.068 141.257 120.122 1.00 42.04  ? 713 LEU A CA  1 
ATOM   5238 C  C   . LEU A 1 713 ? 137.670 141.423 120.705 1.00 42.04  ? 713 LEU A C   1 
ATOM   5239 O  O   . LEU A 1 713 ? 137.527 141.574 121.920 1.00 42.04  ? 713 LEU A O   1 
ATOM   5240 C  CB  . LEU A 1 713 ? 139.645 142.608 119.705 1.00 42.04  ? 713 LEU A CB  1 
ATOM   5241 C  CG  . LEU A 1 713 ? 141.101 142.567 119.241 1.00 42.04  ? 713 LEU A CG  1 
ATOM   5242 C  CD1 . LEU A 1 713 ? 141.500 143.870 118.569 1.00 42.04  ? 713 LEU A CD1 1 
ATOM   5243 C  CD2 . LEU A 1 713 ? 142.021 142.244 120.400 1.00 42.04  ? 713 LEU A CD2 1 
ATOM   5244 N  N   . PHE A 1 714 ? 136.628 141.375 119.874 1.00 40.69  ? 714 PHE A N   1 
ATOM   5245 C  CA  . PHE A 1 714 ? 135.272 141.446 120.406 1.00 40.69  ? 714 PHE A CA  1 
ATOM   5246 C  C   . PHE A 1 714 ? 134.883 140.162 121.126 1.00 40.69  ? 714 PHE A C   1 
ATOM   5247 O  O   . PHE A 1 714 ? 134.122 140.208 122.096 1.00 40.69  ? 714 PHE A O   1 
ATOM   5248 C  CB  . PHE A 1 714 ? 134.274 141.748 119.291 1.00 40.69  ? 714 PHE A CB  1 
ATOM   5249 C  CG  . PHE A 1 714 ? 132.884 142.024 119.786 1.00 40.69  ? 714 PHE A CG  1 
ATOM   5250 C  CD1 . PHE A 1 714 ? 132.583 143.227 120.403 1.00 40.69  ? 714 PHE A CD1 1 
ATOM   5251 C  CD2 . PHE A 1 714 ? 131.879 141.082 119.639 1.00 40.69  ? 714 PHE A CD2 1 
ATOM   5252 C  CE1 . PHE A 1 714 ? 131.306 143.489 120.860 1.00 40.69  ? 714 PHE A CE1 1 
ATOM   5253 C  CE2 . PHE A 1 714 ? 130.600 141.337 120.096 1.00 40.69  ? 714 PHE A CE2 1 
ATOM   5254 C  CZ  . PHE A 1 714 ? 130.314 142.542 120.707 1.00 40.69  ? 714 PHE A CZ  1 
ATOM   5255 N  N   . ILE A 1 715 ? 135.381 139.011 120.665 1.00 36.54  ? 715 ILE A N   1 
ATOM   5256 C  CA  . ILE A 1 715 ? 135.176 137.768 121.406 1.00 36.54  ? 715 ILE A CA  1 
ATOM   5257 C  C   . ILE A 1 715 ? 135.860 137.847 122.764 1.00 36.54  ? 715 ILE A C   1 
ATOM   5258 O  O   . ILE A 1 715 ? 135.289 137.458 123.791 1.00 36.54  ? 715 ILE A O   1 
ATOM   5259 C  CB  . ILE A 1 715 ? 135.674 136.563 120.583 1.00 36.54  ? 715 ILE A CB  1 
ATOM   5260 C  CG1 . ILE A 1 715 ? 134.638 136.173 119.530 1.00 36.54  ? 715 ILE A CG1 1 
ATOM   5261 C  CG2 . ILE A 1 715 ? 135.994 135.369 121.478 1.00 36.54  ? 715 ILE A CG2 1 
ATOM   5262 C  CD1 . ILE A 1 715 ? 135.247 135.728 118.227 1.00 36.54  ? 715 ILE A CD1 1 
ATOM   5263 N  N   . ASN A 1 716 ? 137.063 138.422 122.793 1.00 41.07  ? 716 ASN A N   1 
ATOM   5264 C  CA  . ASN A 1 716 ? 137.818 138.564 124.067 1.00 41.07  ? 716 ASN A CA  1 
ATOM   5265 C  C   . ASN A 1 716 ? 137.132 139.613 124.936 1.00 41.07  ? 716 ASN A C   1 
ATOM   5266 O  O   . ASN A 1 716 ? 137.366 139.610 126.150 1.00 41.07  ? 716 ASN A O   1 
ATOM   5267 C  CB  . ASN A 1 716 ? 139.279 138.941 123.827 1.00 41.07  ? 716 ASN A CB  1 
ATOM   5268 C  CG  . ASN A 1 716 ? 140.118 138.867 125.085 1.00 41.07  ? 716 ASN A CG  1 
ATOM   5269 O  OD1 . ASN A 1 716 ? 140.331 137.790 125.636 1.00 41.07  ? 716 ASN A OD1 1 
ATOM   5270 N  ND2 . ASN A 1 716 ? 140.581 140.012 125.557 1.00 41.07  ? 716 ASN A ND2 1 
ATOM   5271 N  N   . LEU A 1 717 ? 136.402 140.539 124.323 1.00 44.78  ? 717 LEU A N   1 
ATOM   5272 C  CA  . LEU A 1 717 ? 135.615 141.497 125.091 1.00 44.78  ? 717 LEU A CA  1 
ATOM   5273 C  C   . LEU A 1 717 ? 134.391 140.831 125.705 1.00 44.78  ? 717 LEU A C   1 
ATOM   5274 O  O   . LEU A 1 717 ? 134.048 141.078 126.867 1.00 44.78  ? 717 LEU A O   1 
ATOM   5275 C  CB  . LEU A 1 717 ? 135.189 142.648 124.180 1.00 44.78  ? 717 LEU A CB  1 
ATOM   5276 C  CG  . LEU A 1 717 ? 134.351 143.769 124.784 1.00 44.78  ? 717 LEU A CG  1 
ATOM   5277 C  CD1 . LEU A 1 717 ? 135.234 144.947 125.100 1.00 44.78  ? 717 LEU A CD1 1 
ATOM   5278 C  CD2 . LEU A 1 717 ? 133.236 144.177 123.843 1.00 44.78  ? 717 LEU A CD2 1 
ATOM   5279 N  N   . VAL A 1 718 ? 133.717 139.986 124.924 1.00 42.54  ? 718 VAL A N   1 
ATOM   5280 C  CA  . VAL A 1 718 ? 132.473 139.365 125.364 1.00 42.54  ? 718 VAL A CA  1 
ATOM   5281 C  C   . VAL A 1 718 ? 132.748 138.332 126.450 1.00 42.54  ? 718 VAL A C   1 
ATOM   5282 O  O   . VAL A 1 718 ? 132.147 138.369 127.529 1.00 42.54  ? 718 VAL A O   1 
ATOM   5283 C  CB  . VAL A 1 718 ? 131.739 138.755 124.155 1.00 42.54  ? 718 VAL A CB  1 
ATOM   5284 C  CG1 . VAL A 1 718 ? 130.834 137.612 124.573 1.00 42.54  ? 718 VAL A CG1 1 
ATOM   5285 C  CG2 . VAL A 1 718 ? 130.947 139.829 123.431 1.00 42.54  ? 718 VAL A CG2 1 
ATOM   5286 N  N   . ASN A 1 719 ? 133.666 137.409 126.190 1.00 39.39  ? 719 ASN A N   1 
ATOM   5287 C  CA  . ASN A 1 719 ? 134.135 136.462 127.185 1.00 39.39  ? 719 ASN A CA  1 
ATOM   5288 C  C   . ASN A 1 719 ? 135.383 137.041 127.856 1.00 39.39  ? 719 ASN A C   1 
ATOM   5289 O  O   . ASN A 1 719 ? 135.693 138.223 127.680 1.00 39.39  ? 719 ASN A O   1 
ATOM   5290 C  CB  . ASN A 1 719 ? 134.370 135.102 126.524 1.00 39.39  ? 719 ASN A CB  1 
ATOM   5291 C  CG  . ASN A 1 719 ? 133.389 134.826 125.403 1.00 39.39  ? 719 ASN A CG  1 
ATOM   5292 O  OD1 . ASN A 1 719 ? 132.191 134.674 125.637 1.00 39.39  ? 719 ASN A OD1 1 
ATOM   5293 N  ND2 . ASN A 1 719 ? 133.895 134.757 124.178 1.00 39.39  ? 719 ASN A ND2 1 
ATOM   5294 N  N   . ASP A 1 720 ? 136.089 136.218 128.642 1.00 44.53  ? 720 ASP A N   1 
ATOM   5295 C  CA  . ASP A 1 720 ? 137.258 136.629 129.421 1.00 44.53  ? 720 ASP A CA  1 
ATOM   5296 C  C   . ASP A 1 720 ? 136.898 137.818 130.303 1.00 44.53  ? 720 ASP A C   1 
ATOM   5297 O  O   . ASP A 1 720 ? 137.704 138.732 130.504 1.00 44.53  ? 720 ASP A O   1 
ATOM   5298 C  CB  . ASP A 1 720 ? 138.442 136.958 128.505 1.00 44.53  ? 720 ASP A CB  1 
ATOM   5299 C  CG  . ASP A 1 720 ? 139.766 136.488 129.074 1.00 44.53  ? 720 ASP A CG  1 
ATOM   5300 O  OD1 . ASP A 1 720 ? 140.233 137.078 130.069 1.00 44.53  ? 720 ASP A OD1 1 
ATOM   5301 O  OD2 . ASP A 1 720 ? 140.343 135.529 128.519 1.00 44.53  ? 720 ASP A OD2 1 
ATOM   5302 N  N   . SER A 1 721 ? 135.675 137.799 130.826 1.00 43.08  ? 721 SER A N   1 
ATOM   5303 C  CA  . SER A 1 721 ? 135.019 138.976 131.375 1.00 43.08  ? 721 SER A CA  1 
ATOM   5304 C  C   . SER A 1 721 ? 133.900 138.553 132.316 1.00 43.08  ? 721 SER A C   1 
ATOM   5305 O  O   . SER A 1 721 ? 133.941 137.457 132.885 1.00 43.08  ? 721 SER A O   1 
ATOM   5306 C  CB  . SER A 1 721 ? 134.486 139.873 130.256 1.00 43.08  ? 721 SER A CB  1 
ATOM   5307 O  OG  . SER A 1 721 ? 133.632 139.158 129.382 1.00 43.08  ? 721 SER A OG  1 
ATOM   5308 N  N   . LEU A 1 722 ? 132.938 139.452 132.533 1.00 43.57  ? 722 LEU A N   1 
ATOM   5309 C  CA  . LEU A 1 722 ? 131.724 139.263 133.327 1.00 43.57  ? 722 LEU A CA  1 
ATOM   5310 C  C   . LEU A 1 722 ? 131.089 137.870 133.234 1.00 43.57  ? 722 LEU A C   1 
ATOM   5311 O  O   . LEU A 1 722 ? 130.649 137.361 134.269 1.00 43.57  ? 722 LEU A O   1 
ATOM   5312 C  CB  . LEU A 1 722 ? 130.682 140.331 132.963 1.00 43.57  ? 722 LEU A CB  1 
ATOM   5313 C  CG  . LEU A 1 722 ? 131.127 141.794 132.835 1.00 43.57  ? 722 LEU A CG  1 
ATOM   5314 C  CD1 . LEU A 1 722 ? 131.512 142.159 131.401 1.00 43.57  ? 722 LEU A CD1 1 
ATOM   5315 C  CD2 . LEU A 1 722 ? 130.055 142.737 133.368 1.00 43.57  ? 722 LEU A CD2 1 
ATOM   5316 N  N   . PRO A 1 723 ? 130.987 137.216 132.060 1.00 39.43  ? 723 PRO A N   1 
ATOM   5317 C  CA  . PRO A 1 723 ? 130.547 135.806 132.084 1.00 39.43  ? 723 PRO A CA  1 
ATOM   5318 C  C   . PRO A 1 723 ? 131.483 134.880 132.841 1.00 39.43  ? 723 PRO A C   1 
ATOM   5319 O  O   . PRO A 1 723 ? 131.012 134.001 133.573 1.00 39.43  ? 723 PRO A O   1 
ATOM   5320 C  CB  . PRO A 1 723 ? 130.469 135.438 130.595 1.00 39.43  ? 723 PRO A CB  1 
ATOM   5321 C  CG  . PRO A 1 723 ? 131.336 136.421 129.921 1.00 39.43  ? 723 PRO A CG  1 
ATOM   5322 C  CD  . PRO A 1 723 ? 131.080 137.689 130.668 1.00 39.43  ? 723 PRO A CD  1 
ATOM   5323 N  N   . ALA A 1 724 ? 132.799 135.050 132.694 1.00 38.52  ? 724 ALA A N   1 
ATOM   5324 C  CA  . ALA A 1 724 ? 133.735 134.244 133.472 1.00 38.52  ? 724 ALA A CA  1 
ATOM   5325 C  C   . ALA A 1 724 ? 133.645 134.579 134.955 1.00 38.52  ? 724 ALA A C   1 
ATOM   5326 O  O   . ALA A 1 724 ? 133.765 133.692 135.808 1.00 38.52  ? 724 ALA A O   1 
ATOM   5327 C  CB  . ALA A 1 724 ? 135.159 134.446 132.962 1.00 38.52  ? 724 ALA A CB  1 
ATOM   5328 N  N   . ILE A 1 725 ? 133.432 135.857 135.276 1.00 40.66  ? 725 ILE A N   1 
ATOM   5329 C  CA  . ILE A 1 725 ? 133.236 136.264 136.666 1.00 40.66  ? 725 ILE A CA  1 
ATOM   5330 C  C   . ILE A 1 725 ? 132.004 135.581 137.248 1.00 40.66  ? 725 ILE A C   1 
ATOM   5331 O  O   . ILE A 1 725 ? 132.028 135.053 138.366 1.00 40.66  ? 725 ILE A O   1 
ATOM   5332 C  CB  . ILE A 1 725 ? 133.123 137.796 136.763 1.00 40.66  ? 725 ILE A CB  1 
ATOM   5333 C  CG1 . ILE A 1 725 ? 134.242 138.473 135.968 1.00 40.66  ? 725 ILE A CG1 1 
ATOM   5334 C  CG2 . ILE A 1 725 ? 133.127 138.240 138.214 1.00 40.66  ? 725 ILE A CG2 1 
ATOM   5335 C  CD1 . ILE A 1 725 ? 135.627 138.152 136.460 1.00 40.66  ? 725 ILE A CD1 1 
ATOM   5336 N  N   . ALA A 1 726 ? 130.910 135.574 136.485 1.00 44.80  ? 726 ALA A N   1 
ATOM   5337 C  CA  . ALA A 1 726 ? 129.679 134.925 136.918 1.00 44.80  ? 726 ALA A CA  1 
ATOM   5338 C  C   . ALA A 1 726 ? 129.854 133.422 137.064 1.00 44.80  ? 726 ALA A C   1 
ATOM   5339 O  O   . ALA A 1 726 ? 129.276 132.817 137.974 1.00 44.80  ? 726 ALA A O   1 
ATOM   5340 C  CB  . ALA A 1 726 ? 128.560 135.230 135.926 1.00 44.80  ? 726 ALA A CB  1 
ATOM   5341 N  N   . LEU A 1 727 ? 130.627 132.803 136.171 1.00 38.17  ? 727 LEU A N   1 
ATOM   5342 C  CA  . LEU A 1 727 ? 130.911 131.381 136.306 1.00 38.17  ? 727 LEU A CA  1 
ATOM   5343 C  C   . LEU A 1 727 ? 131.768 131.104 137.534 1.00 38.17  ? 727 LEU A C   1 
ATOM   5344 O  O   . LEU A 1 727 ? 131.659 130.031 138.138 1.00 38.17  ? 727 LEU A O   1 
ATOM   5345 C  CB  . LEU A 1 727 ? 131.586 130.860 135.039 1.00 38.17  ? 727 LEU A CB  1 
ATOM   5346 C  CG  . LEU A 1 727 ? 130.790 129.768 134.325 1.00 38.17  ? 727 LEU A CG  1 
ATOM   5347 C  CD1 . LEU A 1 727 ? 131.625 129.076 133.269 1.00 38.17  ? 727 LEU A CD1 1 
ATOM   5348 C  CD2 . LEU A 1 727 ? 130.267 128.767 135.330 1.00 38.17  ? 727 LEU A CD2 1 
ATOM   5349 N  N   . GLY A 1 728 ? 132.625 132.052 137.910 1.00 42.38  ? 728 GLY A N   1 
ATOM   5350 C  CA  . GLY A 1 728 ? 133.300 131.991 139.193 1.00 42.38  ? 728 GLY A CA  1 
ATOM   5351 C  C   . GLY A 1 728 ? 132.410 132.307 140.377 1.00 42.38  ? 728 GLY A C   1 
ATOM   5352 O  O   . GLY A 1 728 ? 132.806 132.045 141.518 1.00 42.38  ? 728 GLY A O   1 
ATOM   5353 N  N   . MET A 1 729 ? 131.230 132.872 140.134 1.00 42.97  ? 729 MET A N   1 
ATOM   5354 C  CA  . MET A 1 729 ? 130.228 133.092 141.169 1.00 42.97  ? 729 MET A CA  1 
ATOM   5355 C  C   . MET A 1 729 ? 129.282 131.907 141.328 1.00 42.97  ? 729 MET A C   1 
ATOM   5356 O  O   . MET A 1 729 ? 128.242 132.043 141.980 1.00 42.97  ? 729 MET A O   1 
ATOM   5357 C  CB  . MET A 1 729 ? 129.420 134.356 140.861 1.00 42.97  ? 729 MET A CB  1 
ATOM   5358 C  CG  . MET A 1 729 ? 130.208 135.653 140.946 1.00 42.97  ? 729 MET A CG  1 
ATOM   5359 S  SD  . MET A 1 729 ? 130.886 136.000 142.576 1.00 42.97  ? 729 MET A SD  1 
ATOM   5360 C  CE  . MET A 1 729 ? 129.985 137.494 142.981 1.00 42.97  ? 729 MET A CE  1 
ATOM   5361 N  N   . GLU A 1 730 ? 129.614 130.760 140.739 1.00 49.58  ? 730 GLU A N   1 
ATOM   5362 C  CA  . GLU A 1 730 ? 128.736 129.597 140.770 1.00 49.58  ? 730 GLU A CA  1 
ATOM   5363 C  C   . GLU A 1 730 ? 128.624 129.035 142.184 1.00 49.58  ? 730 GLU A C   1 
ATOM   5364 O  O   . GLU A 1 730 ? 129.606 128.983 142.930 1.00 49.58  ? 730 GLU A O   1 
ATOM   5365 C  CB  . GLU A 1 730 ? 129.257 128.532 139.798 1.00 49.58  ? 730 GLU A CB  1 
ATOM   5366 C  CG  . GLU A 1 730 ? 128.874 127.093 140.113 1.00 49.58  ? 730 GLU A CG  1 
ATOM   5367 C  CD  . GLU A 1 730 ? 127.516 126.711 139.557 1.00 49.58  ? 730 GLU A CD  1 
ATOM   5368 O  OE1 . GLU A 1 730 ? 127.142 127.231 138.485 1.00 49.58  ? 730 GLU A OE1 1 
ATOM   5369 O  OE2 . GLU A 1 730 ? 126.821 125.889 140.192 1.00 49.58  ? 730 GLU A OE2 1 
ATOM   5370 N  N   . LYS A 1 731 ? 127.414 128.614 142.550 1.00 57.10  ? 731 LYS A N   1 
ATOM   5371 C  CA  . LYS A 1 731 ? 127.133 128.101 143.885 1.00 57.10  ? 731 LYS A CA  1 
ATOM   5372 C  C   . LYS A 1 731 ? 127.706 126.691 144.041 1.00 57.10  ? 731 LYS A C   1 
ATOM   5373 O  O   . LYS A 1 731 ? 128.403 126.170 143.167 1.00 57.10  ? 731 LYS A O   1 
ATOM   5374 C  CB  . LYS A 1 731 ? 125.631 128.135 144.153 1.00 57.10  ? 731 LYS A CB  1 
ATOM   5375 C  CG  . LYS A 1 731 ? 125.087 129.518 144.464 1.00 57.10  ? 731 LYS A CG  1 
ATOM   5376 C  CD  . LYS A 1 731 ? 125.682 130.068 145.749 1.00 57.10  ? 731 LYS A CD  1 
ATOM   5377 C  CE  . LYS A 1 731 ? 125.250 129.248 146.954 1.00 57.10  ? 731 LYS A CE  1 
ATOM   5378 N  NZ  . LYS A 1 731 ? 123.786 129.354 147.199 1.00 57.10  ? 731 LYS A NZ  1 
ATOM   5379 N  N   . ALA A 1 732 ? 127.409 126.053 145.169 1.00 59.98  ? 732 ALA A N   1 
ATOM   5380 C  CA  . ALA A 1 732 ? 127.978 124.748 145.482 1.00 59.98  ? 732 ALA A CA  1 
ATOM   5381 C  C   . ALA A 1 732 ? 127.232 123.655 144.725 1.00 59.98  ? 732 ALA A C   1 
ATOM   5382 O  O   . ALA A 1 732 ? 126.009 123.530 144.846 1.00 59.98  ? 732 ALA A O   1 
ATOM   5383 C  CB  . ALA A 1 732 ? 127.923 124.493 146.986 1.00 59.98  ? 732 ALA A CB  1 
ATOM   5384 N  N   . GLU A 1 733 ? 127.969 122.867 143.945 1.00 59.96  ? 733 GLU A N   1 
ATOM   5385 C  CA  . GLU A 1 733 ? 127.393 121.693 143.313 1.00 59.96  ? 733 GLU A CA  1 
ATOM   5386 C  C   . GLU A 1 733 ? 127.100 120.629 144.373 1.00 59.96  ? 733 GLU A C   1 
ATOM   5387 O  O   . GLU A 1 733 ? 127.736 120.607 145.429 1.00 59.96  ? 733 GLU A O   1 
ATOM   5388 C  CB  . GLU A 1 733 ? 128.341 121.146 142.245 1.00 59.96  ? 733 GLU A CB  1 
ATOM   5389 C  CG  . GLU A 1 733 ? 129.740 120.831 142.733 1.00 59.96  ? 733 GLU A CG  1 
ATOM   5390 C  CD  . GLU A 1 733 ? 130.706 121.977 142.504 1.00 59.96  ? 733 GLU A CD  1 
ATOM   5391 O  OE1 . GLU A 1 733 ? 130.240 123.116 142.292 1.00 59.96  ? 733 GLU A OE1 1 
ATOM   5392 O  OE2 . GLU A 1 733 ? 131.931 121.737 142.532 1.00 59.96  ? 733 GLU A OE2 1 
ATOM   5393 N  N   . PRO A 1 734 ? 126.133 119.737 144.122 1.00 59.55  ? 734 PRO A N   1 
ATOM   5394 C  CA  . PRO A 1 734 ? 125.694 118.799 145.172 1.00 59.55  ? 734 PRO A CA  1 
ATOM   5395 C  C   . PRO A 1 734 ? 126.727 117.764 145.607 1.00 59.55  ? 734 PRO A C   1 
ATOM   5396 O  O   . PRO A 1 734 ? 126.387 116.898 146.421 1.00 59.55  ? 734 PRO A O   1 
ATOM   5397 C  CB  . PRO A 1 734 ? 124.479 118.108 144.533 1.00 59.55  ? 734 PRO A CB  1 
ATOM   5398 C  CG  . PRO A 1 734 ? 123.998 119.061 143.503 1.00 59.55  ? 734 PRO A CG  1 
ATOM   5399 C  CD  . PRO A 1 734 ? 125.230 119.705 142.958 1.00 59.55  ? 734 PRO A CD  1 
ATOM   5400 N  N   . ASP A 1 735 ? 127.966 117.804 145.113 1.00 60.37  ? 735 ASP A N   1 
ATOM   5401 C  CA  . ASP A 1 735 ? 128.952 116.778 145.435 1.00 60.37  ? 735 ASP A CA  1 
ATOM   5402 C  C   . ASP A 1 735 ? 130.237 117.359 146.025 1.00 60.37  ? 735 ASP A C   1 
ATOM   5403 O  O   . ASP A 1 735 ? 131.247 116.652 146.118 1.00 60.37  ? 735 ASP A O   1 
ATOM   5404 C  CB  . ASP A 1 735 ? 129.243 115.939 144.187 1.00 60.37  ? 735 ASP A CB  1 
ATOM   5405 C  CG  . ASP A 1 735 ? 130.322 116.541 143.310 1.00 60.37  ? 735 ASP A CG  1 
ATOM   5406 O  OD1 . ASP A 1 735 ? 130.010 117.474 142.548 1.00 60.37  ? 735 ASP A OD1 1 
ATOM   5407 O  OD2 . ASP A 1 735 ? 131.472 116.063 143.363 1.00 60.37  ? 735 ASP A OD2 1 
ATOM   5408 N  N   . VAL A 1 736 ? 130.206 118.620 146.471 1.00 54.10  ? 736 VAL A N   1 
ATOM   5409 C  CA  . VAL A 1 736 ? 131.403 119.249 147.030 1.00 54.10  ? 736 VAL A CA  1 
ATOM   5410 C  C   . VAL A 1 736 ? 131.842 118.540 148.305 1.00 54.10  ? 736 VAL A C   1 
ATOM   5411 O  O   . VAL A 1 736 ? 133.041 118.419 148.582 1.00 54.10  ? 736 VAL A O   1 
ATOM   5412 C  CB  . VAL A 1 736 ? 131.164 120.750 147.276 1.00 54.10  ? 736 VAL A CB  1 
ATOM   5413 C  CG1 . VAL A 1 736 ? 131.293 121.529 145.981 1.00 54.10  ? 736 VAL A CG1 1 
ATOM   5414 C  CG2 . VAL A 1 736 ? 129.804 120.983 147.918 1.00 54.10  ? 736 VAL A CG2 1 
ATOM   5415 N  N   . MET A 1 737 ? 130.887 118.060 149.097 1.00 56.27  ? 737 MET A N   1 
ATOM   5416 C  CA  . MET A 1 737 ? 131.185 117.311 150.308 1.00 56.27  ? 737 MET A CA  1 
ATOM   5417 C  C   . MET A 1 737 ? 131.229 115.808 150.066 1.00 56.27  ? 737 MET A C   1 
ATOM   5418 O  O   . MET A 1 737 ? 131.254 115.037 151.030 1.00 56.27  ? 737 MET A O   1 
ATOM   5419 C  CB  . MET A 1 737 ? 130.154 117.636 151.396 1.00 56.27  ? 737 MET A CB  1 
ATOM   5420 C  CG  . MET A 1 737 ? 130.058 119.116 151.794 1.00 56.27  ? 737 MET A CG  1 
ATOM   5421 S  SD  . MET A 1 737 ? 131.525 120.033 152.349 1.00 56.27  ? 737 MET A SD  1 
ATOM   5422 C  CE  . MET A 1 737 ? 132.518 118.805 153.203 1.00 56.27  ? 737 MET A CE  1 
ATOM   5423 N  N   . LYS A 1 738 ? 131.224 115.377 148.805 1.00 53.85  ? 738 LYS A N   1 
ATOM   5424 C  CA  . LYS A 1 738 ? 131.276 113.964 148.457 1.00 53.85  ? 738 LYS A CA  1 
ATOM   5425 C  C   . LYS A 1 738 ? 132.598 113.565 147.813 1.00 53.85  ? 738 LYS A C   1 
ATOM   5426 O  O   . LYS A 1 738 ? 132.741 112.418 147.378 1.00 53.85  ? 738 LYS A O   1 
ATOM   5427 C  CB  . LYS A 1 738 ? 130.113 113.608 147.528 1.00 53.85  ? 738 LYS A CB  1 
ATOM   5428 C  CG  . LYS A 1 738 ? 128.755 114.077 148.024 1.00 53.85  ? 738 LYS A CG  1 
ATOM   5429 C  CD  . LYS A 1 738 ? 128.420 113.479 149.378 1.00 53.85  ? 738 LYS A CD  1 
ATOM   5430 C  CE  . LYS A 1 738 ? 126.945 113.647 149.703 1.00 53.85  ? 738 LYS A CE  1 
ATOM   5431 N  NZ  . LYS A 1 738 ? 126.529 115.075 149.655 1.00 53.85  ? 738 LYS A NZ  1 
ATOM   5432 N  N   . ARG A 1 739 ? 133.565 114.476 147.741 1.00 58.66  ? 739 ARG A N   1 
ATOM   5433 C  CA  . ARG A 1 739 ? 134.850 114.207 147.115 1.00 58.66  ? 739 ARG A CA  1 
ATOM   5434 C  C   . ARG A 1 739 ? 135.962 114.191 148.153 1.00 58.66  ? 739 ARG A C   1 
ATOM   5435 O  O   . ARG A 1 739 ? 135.827 114.731 149.254 1.00 58.66  ? 739 ARG A O   1 
ATOM   5436 C  CB  . ARG A 1 739 ? 135.183 115.254 146.047 1.00 58.66  ? 739 ARG A CB  1 
ATOM   5437 C  CG  . ARG A 1 739 ? 134.267 115.261 144.844 1.00 58.66  ? 739 ARG A CG  1 
ATOM   5438 C  CD  . ARG A 1 739 ? 134.637 116.394 143.897 1.00 58.66  ? 739 ARG A CD  1 
ATOM   5439 N  NE  . ARG A 1 739 ? 134.245 117.699 144.418 1.00 58.66  ? 739 ARG A NE  1 
ATOM   5440 C  CZ  . ARG A 1 739 ? 135.084 118.572 144.960 1.00 58.66  ? 739 ARG A CZ  1 
ATOM   5441 N  NH1 . ARG A 1 739 ? 136.377 118.315 145.064 1.00 58.66  ? 739 ARG A NH1 1 
ATOM   5442 N  NH2 . ARG A 1 739 ? 134.613 119.732 145.407 1.00 58.66  ? 739 ARG A NH2 1 
ATOM   5443 N  N   . LYS A 1 740 ? 137.073 113.562 147.777 1.00 52.26  ? 740 LYS A N   1 
ATOM   5444 C  CA  . LYS A 1 740 ? 138.279 113.613 148.583 1.00 52.26  ? 740 LYS A CA  1 
ATOM   5445 C  C   . LYS A 1 740 ? 138.846 115.034 148.585 1.00 52.26  ? 740 LYS A C   1 
ATOM   5446 O  O   . LYS A 1 740 ? 138.630 115.795 147.638 1.00 52.26  ? 740 LYS A O   1 
ATOM   5447 C  CB  . LYS A 1 740 ? 139.319 112.634 148.041 1.00 52.26  ? 740 LYS A CB  1 
ATOM   5448 C  CG  . LYS A 1 740 ? 139.071 111.187 148.428 1.00 52.26  ? 740 LYS A CG  1 
ATOM   5449 C  CD  . LYS A 1 740 ? 139.142 111.005 149.934 1.00 52.26  ? 740 LYS A CD  1 
ATOM   5450 C  CE  . LYS A 1 740 ? 138.969 109.547 150.322 1.00 52.26  ? 740 LYS A CE  1 
ATOM   5451 N  NZ  . LYS A 1 740 ? 139.101 109.350 151.792 1.00 52.26  ? 740 LYS A NZ  1 
ATOM   5452 N  N   . PRO A 1 741 ? 139.555 115.423 149.646 1.00 54.94  ? 741 PRO A N   1 
ATOM   5453 C  CA  . PRO A 1 741 ? 140.117 116.777 149.695 1.00 54.94  ? 741 PRO A CA  1 
ATOM   5454 C  C   . PRO A 1 741 ? 141.185 116.993 148.634 1.00 54.94  ? 741 PRO A C   1 
ATOM   5455 O  O   . PRO A 1 741 ? 141.845 116.056 148.178 1.00 54.94  ? 741 PRO A O   1 
ATOM   5456 C  CB  . PRO A 1 741 ? 140.716 116.869 151.104 1.00 54.94  ? 741 PRO A CB  1 
ATOM   5457 C  CG  . PRO A 1 741 ? 140.072 115.778 151.880 1.00 54.94  ? 741 PRO A CG  1 
ATOM   5458 C  CD  . PRO A 1 741 ? 139.785 114.689 150.902 1.00 54.94  ? 741 PRO A CD  1 
ATOM   5459 N  N   . ARG A 1 742 ? 141.333 118.254 148.236 1.00 69.13  ? 742 ARG A N   1 
ATOM   5460 C  CA  . ARG A 1 742 ? 142.377 118.639 147.297 1.00 69.13  ? 742 ARG A CA  1 
ATOM   5461 C  C   . ARG A 1 742 ? 143.752 118.410 147.918 1.00 69.13  ? 742 ARG A C   1 
ATOM   5462 O  O   . ARG A 1 742 ? 143.923 118.468 149.139 1.00 69.13  ? 742 ARG A O   1 
ATOM   5463 C  CB  . ARG A 1 742 ? 142.203 120.109 146.900 1.00 69.13  ? 742 ARG A CB  1 
ATOM   5464 C  CG  . ARG A 1 742 ? 143.118 120.605 145.787 1.00 69.13  ? 742 ARG A CG  1 
ATOM   5465 C  CD  . ARG A 1 742 ? 143.566 122.038 146.039 1.00 69.13  ? 742 ARG A CD  1 
ATOM   5466 N  NE  . ARG A 1 742 ? 144.526 122.129 147.133 1.00 69.13  ? 742 ARG A NE  1 
ATOM   5467 C  CZ  . ARG A 1 742 ? 145.223 123.217 147.434 1.00 69.13  ? 742 ARG A CZ  1 
ATOM   5468 N  NH1 . ARG A 1 742 ? 145.098 124.333 146.736 1.00 69.13  ? 742 ARG A NH1 1 
ATOM   5469 N  NH2 . ARG A 1 742 ? 146.070 123.182 148.459 1.00 69.13  ? 742 ARG A NH2 1 
ATOM   5470 N  N   . ASP A 1 743 ? 144.736 118.129 147.066 1.00 76.79  ? 743 ASP A N   1 
ATOM   5471 C  CA  . ASP A 1 743 ? 146.107 117.958 147.518 1.00 76.79  ? 743 ASP A CA  1 
ATOM   5472 C  C   . ASP A 1 743 ? 146.656 119.275 148.068 1.00 76.79  ? 743 ASP A C   1 
ATOM   5473 O  O   . ASP A 1 743 ? 146.062 120.344 147.907 1.00 76.79  ? 743 ASP A O   1 
ATOM   5474 C  CB  . ASP A 1 743 ? 146.986 117.450 146.377 1.00 76.79  ? 743 ASP A CB  1 
ATOM   5475 C  CG  . ASP A 1 743 ? 148.073 116.508 146.854 1.00 76.79  ? 743 ASP A CG  1 
ATOM   5476 O  OD1 . ASP A 1 743 ? 148.567 116.694 147.985 1.00 76.79  ? 743 ASP A OD1 1 
ATOM   5477 O  OD2 . ASP A 1 743 ? 148.434 115.583 146.097 1.00 76.79  ? 743 ASP A OD2 1 
ATOM   5478 N  N   . ILE A 1 744 ? 147.807 119.183 148.740 1.00 77.99  ? 744 ILE A N   1 
ATOM   5479 C  CA  . ILE A 1 744 ? 148.411 120.367 149.350 1.00 77.99  ? 744 ILE A CA  1 
ATOM   5480 C  C   . ILE A 1 744 ? 148.826 121.369 148.278 1.00 77.99  ? 744 ILE A C   1 
ATOM   5481 O  O   . ILE A 1 744 ? 148.633 122.582 148.432 1.00 77.99  ? 744 ILE A O   1 
ATOM   5482 C  CB  . ILE A 1 744 ? 149.591 119.960 150.257 1.00 77.99  ? 744 ILE A CB  1 
ATOM   5483 C  CG1 . ILE A 1 744 ? 150.403 121.187 150.685 1.00 77.99  ? 744 ILE A CG1 1 
ATOM   5484 C  CG2 . ILE A 1 744 ? 150.472 118.916 149.578 1.00 77.99  ? 744 ILE A CG2 1 
ATOM   5485 C  CD1 . ILE A 1 744 ? 151.550 120.867 151.618 1.00 77.99  ? 744 ILE A CD1 1 
ATOM   5486 N  N   . ASN A 1 745 ? 149.377 120.881 147.169 1.00 76.22  ? 745 ASN A N   1 
ATOM   5487 C  CA  . ASN A 1 745 ? 149.659 121.743 146.033 1.00 76.22  ? 745 ASN A CA  1 
ATOM   5488 C  C   . ASN A 1 745 ? 148.354 122.223 145.402 1.00 76.22  ? 745 ASN A C   1 
ATOM   5489 O  O   . ASN A 1 745 ? 147.282 121.651 145.619 1.00 76.22  ? 745 ASN A O   1 
ATOM   5490 C  CB  . ASN A 1 745 ? 150.511 121.009 144.998 1.00 76.22  ? 745 ASN A CB  1 
ATOM   5491 C  CG  . ASN A 1 745 ? 149.779 119.846 144.359 1.00 76.22  ? 745 ASN A CG  1 
ATOM   5492 O  OD1 . ASN A 1 745 ? 149.132 119.998 143.322 1.00 76.22  ? 745 ASN A OD1 1 
ATOM   5493 N  ND2 . ASN A 1 745 ? 149.877 118.675 144.977 1.00 76.22  ? 745 ASN A ND2 1 
ATOM   5494 N  N   . GLU A 1 746 ? 148.457 123.303 144.623 1.00 73.81  ? 746 GLU A N   1 
ATOM   5495 C  CA  . GLU A 1 746 ? 147.269 123.911 144.031 1.00 73.81  ? 746 GLU A CA  1 
ATOM   5496 C  C   . GLU A 1 746 ? 146.583 122.956 143.059 1.00 73.81  ? 746 GLU A C   1 
ATOM   5497 O  O   . GLU A 1 746 ? 145.382 122.689 143.180 1.00 73.81  ? 746 GLU A O   1 
ATOM   5498 C  CB  . GLU A 1 746 ? 147.645 125.219 143.335 1.00 73.81  ? 746 GLU A CB  1 
ATOM   5499 C  CG  . GLU A 1 746 ? 147.797 126.402 144.282 1.00 73.81  ? 746 GLU A CG  1 
ATOM   5500 C  CD  . GLU A 1 746 ? 149.154 126.444 144.960 1.00 73.81  ? 746 GLU A CD  1 
ATOM   5501 O  OE1 . GLU A 1 746 ? 150.034 125.638 144.590 1.00 73.81  ? 746 GLU A OE1 1 
ATOM   5502 O  OE2 . GLU A 1 746 ? 149.340 127.281 145.868 1.00 73.81  ? 746 GLU A OE2 1 
ATOM   5503 N  N   . GLY A 1 747 ? 147.339 122.411 142.107 1.00 68.98  ? 747 GLY A N   1 
ATOM   5504 C  CA  . GLY A 1 747 ? 146.806 121.443 141.167 1.00 68.98  ? 747 GLY A CA  1 
ATOM   5505 C  C   . GLY A 1 747 ? 145.686 121.975 140.296 1.00 68.98  ? 747 GLY A C   1 
ATOM   5506 O  O   . GLY A 1 747 ? 144.645 121.325 140.154 1.00 68.98  ? 747 GLY A O   1 
ATOM   5507 N  N   . ILE A 1 748 ? 145.882 123.168 139.728 1.00 63.30  ? 748 ILE A N   1 
ATOM   5508 C  CA  . ILE A 1 748 ? 144.858 123.776 138.881 1.00 63.30  ? 748 ILE A CA  1 
ATOM   5509 C  C   . ILE A 1 748 ? 144.621 122.925 137.641 1.00 63.30  ? 748 ILE A C   1 
ATOM   5510 O  O   . ILE A 1 748 ? 143.475 122.693 137.236 1.00 63.30  ? 748 ILE A O   1 
ATOM   5511 C  CB  . ILE A 1 748 ? 145.260 125.216 138.515 1.00 63.30  ? 748 ILE A CB  1 
ATOM   5512 C  CG1 . ILE A 1 748 ? 145.347 126.072 139.778 1.00 63.30  ? 748 ILE A CG1 1 
ATOM   5513 C  CG2 . ILE A 1 748 ? 144.270 125.822 137.529 1.00 63.30  ? 748 ILE A CG2 1 
ATOM   5514 C  CD1 . ILE A 1 748 ? 144.032 126.224 140.494 1.00 63.30  ? 748 ILE A CD1 1 
ATOM   5515 N  N   . PHE A 1 749 ? 145.696 122.434 137.030 1.00 63.34  ? 749 PHE A N   1 
ATOM   5516 C  CA  . PHE A 1 749 ? 145.602 121.572 135.852 1.00 63.34  ? 749 PHE A CA  1 
ATOM   5517 C  C   . PHE A 1 749 ? 145.449 120.106 136.267 1.00 63.34  ? 749 PHE A C   1 
ATOM   5518 O  O   . PHE A 1 749 ? 146.277 119.248 135.963 1.00 63.34  ? 749 PHE A O   1 
ATOM   5519 C  CB  . PHE A 1 749 ? 146.817 121.777 134.953 1.00 63.34  ? 749 PHE A CB  1 
ATOM   5520 C  CG  . PHE A 1 749 ? 148.084 122.094 135.702 1.00 63.34  ? 749 PHE A CG  1 
ATOM   5521 C  CD1 . PHE A 1 749 ? 148.866 121.079 136.231 1.00 63.34  ? 749 PHE A CD1 1 
ATOM   5522 C  CD2 . PHE A 1 749 ? 148.502 123.407 135.864 1.00 63.34  ? 749 PHE A CD2 1 
ATOM   5523 C  CE1 . PHE A 1 749 ? 150.032 121.367 136.917 1.00 63.34  ? 749 PHE A CE1 1 
ATOM   5524 C  CE2 . PHE A 1 749 ? 149.667 123.701 136.549 1.00 63.34  ? 749 PHE A CE2 1 
ATOM   5525 C  CZ  . PHE A 1 749 ? 150.433 122.679 137.075 1.00 63.34  ? 749 PHE A CZ  1 
ATOM   5526 N  N   . ALA A 1 750 ? 144.359 119.832 136.982 1.00 57.21  ? 750 ALA A N   1 
ATOM   5527 C  CA  . ALA A 1 750 ? 144.040 118.468 137.378 1.00 57.21  ? 750 ALA A CA  1 
ATOM   5528 C  C   . ALA A 1 750 ? 143.682 117.630 136.156 1.00 57.21  ? 750 ALA A C   1 
ATOM   5529 O  O   . ALA A 1 750 ? 143.200 118.147 135.147 1.00 57.21  ? 750 ALA A O   1 
ATOM   5530 C  CB  . ALA A 1 750 ? 142.886 118.455 138.379 1.00 57.21  ? 750 ALA A CB  1 
ATOM   5531 N  N   . GLY A 1 751 ? 143.930 116.321 136.258 1.00 59.05  ? 751 GLY A N   1 
ATOM   5532 C  CA  . GLY A 1 751 ? 143.730 115.443 135.113 1.00 59.05  ? 751 GLY A CA  1 
ATOM   5533 C  C   . GLY A 1 751 ? 142.290 115.397 134.637 1.00 59.05  ? 751 GLY A C   1 
ATOM   5534 O  O   . GLY A 1 751 ? 142.023 115.440 133.433 1.00 59.05  ? 751 GLY A O   1 
ATOM   5535 N  N   . GLY A 1 752 ? 141.343 115.321 135.574 1.00 58.13  ? 752 GLY A N   1 
ATOM   5536 C  CA  . GLY A 1 752 ? 139.939 115.368 135.196 1.00 58.13  ? 752 GLY A CA  1 
ATOM   5537 C  C   . GLY A 1 752 ? 139.547 116.705 134.597 1.00 58.13  ? 752 GLY A C   1 
ATOM   5538 O  O   . GLY A 1 752 ? 138.866 116.767 133.568 1.00 58.13  ? 752 GLY A O   1 
ATOM   5539 N  N   . THR A 1 753 ? 139.994 117.800 135.218 1.00 50.95  ? 753 THR A N   1 
ATOM   5540 C  CA  . THR A 1 753 ? 139.672 119.109 134.667 1.00 50.95  ? 753 THR A CA  1 
ATOM   5541 C  C   . THR A 1 753 ? 140.469 119.392 133.397 1.00 50.95  ? 753 THR A C   1 
ATOM   5542 O  O   . THR A 1 753 ? 140.002 120.145 132.543 1.00 50.95  ? 753 THR A O   1 
ATOM   5543 C  CB  . THR A 1 753 ? 139.875 120.206 135.722 1.00 50.95  ? 753 THR A CB  1 
ATOM   5544 O  OG1 . THR A 1 753 ? 141.237 120.191 136.169 1.00 50.95  ? 753 THR A OG1 1 
ATOM   5545 C  CG2 . THR A 1 753 ? 138.963 120.021 136.924 1.00 50.95  ? 753 THR A CG2 1 
ATOM   5546 N  N   . MET A 1 754 ? 141.638 118.763 133.221 1.00 53.56  ? 754 MET A N   1 
ATOM   5547 C  CA  . MET A 1 754 ? 142.348 118.898 131.950 1.00 53.56  ? 754 MET A CA  1 
ATOM   5548 C  C   . MET A 1 754 ? 141.616 118.161 130.837 1.00 53.56  ? 754 MET A C   1 
ATOM   5549 O  O   . MET A 1 754 ? 141.548 118.649 129.702 1.00 53.56  ? 754 MET A O   1 
ATOM   5550 C  CB  . MET A 1 754 ? 143.783 118.388 132.073 1.00 53.56  ? 754 MET A CB  1 
ATOM   5551 C  CG  . MET A 1 754 ? 144.633 118.616 130.834 1.00 53.56  ? 754 MET A CG  1 
ATOM   5552 S  SD  . MET A 1 754 ? 144.446 120.279 130.163 1.00 53.56  ? 754 MET A SD  1 
ATOM   5553 C  CE  . MET A 1 754 ? 145.772 120.312 128.960 1.00 53.56  ? 754 MET A CE  1 
ATOM   5554 N  N   . ARG A 1 755 ? 141.068 116.982 131.143 1.00 55.66  ? 755 ARG A N   1 
ATOM   5555 C  CA  . ARG A 1 755 ? 140.229 116.280 130.178 1.00 55.66  ? 755 ARG A CA  1 
ATOM   5556 C  C   . ARG A 1 755 ? 138.993 117.100 129.831 1.00 55.66  ? 755 ARG A C   1 
ATOM   5557 O  O   . ARG A 1 755 ? 138.600 117.182 128.660 1.00 55.66  ? 755 ARG A O   1 
ATOM   5558 C  CB  . ARG A 1 755 ? 139.828 114.912 130.730 1.00 55.66  ? 755 ARG A CB  1 
ATOM   5559 C  CG  . ARG A 1 755 ? 139.495 113.881 129.667 1.00 55.66  ? 755 ARG A CG  1 
ATOM   5560 C  CD  . ARG A 1 755 ? 139.303 112.505 130.284 1.00 55.66  ? 755 ARG A CD  1 
ATOM   5561 N  NE  . ARG A 1 755 ? 139.338 111.448 129.281 1.00 55.66  ? 755 ARG A NE  1 
ATOM   5562 C  CZ  . ARG A 1 755 ? 140.433 110.790 128.925 1.00 55.66  ? 755 ARG A CZ  1 
ATOM   5563 N  NH1 . ARG A 1 755 ? 141.608 111.056 129.473 1.00 55.66  ? 755 ARG A NH1 1 
ATOM   5564 N  NH2 . ARG A 1 755 ? 140.348 109.842 127.996 1.00 55.66  ? 755 ARG A NH2 1 
ATOM   5565 N  N   . ALA A 1 756 ? 138.376 117.723 130.840 1.00 48.96  ? 756 ALA A N   1 
ATOM   5566 C  CA  . ALA A 1 756 ? 137.227 118.588 130.587 1.00 48.96  ? 756 ALA A CA  1 
ATOM   5567 C  C   . ALA A 1 756 ? 137.611 119.776 129.713 1.00 48.96  ? 756 ALA A C   1 
ATOM   5568 O  O   . ALA A 1 756 ? 136.877 120.131 128.785 1.00 48.96  ? 756 ALA A O   1 
ATOM   5569 C  CB  . ALA A 1 756 ? 136.627 119.068 131.908 1.00 48.96  ? 756 ALA A CB  1 
ATOM   5570 N  N   . VAL A 1 757 ? 138.772 120.382 129.979 1.00 48.89  ? 757 VAL A N   1 
ATOM   5571 C  CA  . VAL A 1 757 ? 139.235 121.527 129.199 1.00 48.89  ? 757 VAL A CA  1 
ATOM   5572 C  C   . VAL A 1 757 ? 139.472 121.126 127.750 1.00 48.89  ? 757 VAL A C   1 
ATOM   5573 O  O   . VAL A 1 757 ? 139.037 121.814 126.819 1.00 48.89  ? 757 VAL A O   1 
ATOM   5574 C  CB  . VAL A 1 757 ? 140.510 122.122 129.826 1.00 48.89  ? 757 VAL A CB  1 
ATOM   5575 C  CG1 . VAL A 1 757 ? 141.273 122.963 128.811 1.00 48.89  ? 757 VAL A CG1 1 
ATOM   5576 C  CG2 . VAL A 1 757 ? 140.166 122.959 131.028 1.00 48.89  ? 757 VAL A CG2 1 
ATOM   5577 N  N   . ILE A 1 758 ? 140.169 120.007 127.538 1.00 46.94  ? 758 ILE A N   1 
ATOM   5578 C  CA  . ILE A 1 758 ? 140.519 119.616 126.178 1.00 46.94  ? 758 ILE A CA  1 
ATOM   5579 C  C   . ILE A 1 758 ? 139.277 119.186 125.403 1.00 46.94  ? 758 ILE A C   1 
ATOM   5580 O  O   . ILE A 1 758 ? 139.134 119.519 124.224 1.00 46.94  ? 758 ILE A O   1 
ATOM   5581 C  CB  . ILE A 1 758 ? 141.630 118.543 126.174 1.00 46.94  ? 758 ILE A CB  1 
ATOM   5582 C  CG1 . ILE A 1 758 ? 142.245 118.414 124.778 1.00 46.94  ? 758 ILE A CG1 1 
ATOM   5583 C  CG2 . ILE A 1 758 ? 141.151 117.188 126.676 1.00 46.94  ? 758 ILE A CG2 1 
ATOM   5584 C  CD1 . ILE A 1 758 ? 143.229 119.506 124.445 1.00 46.94  ? 758 ILE A CD1 1 
ATOM   5585 N  N   . SER A 1 759 ? 138.329 118.502 126.057 1.00 43.82  ? 759 SER A N   1 
ATOM   5586 C  CA  . SER A 1 759 ? 137.098 118.127 125.367 1.00 43.82  ? 759 SER A CA  1 
ATOM   5587 C  C   . SER A 1 759 ? 136.249 119.351 125.044 1.00 43.82  ? 759 SER A C   1 
ATOM   5588 O  O   . SER A 1 759 ? 135.744 119.485 123.922 1.00 43.82  ? 759 SER A O   1 
ATOM   5589 C  CB  . SER A 1 759 ? 136.305 117.133 126.211 1.00 43.82  ? 759 SER A CB  1 
ATOM   5590 O  OG  . SER A 1 759 ? 134.916 117.263 125.969 1.00 43.82  ? 759 SER A OG  1 
ATOM   5591 N  N   . ARG A 1 760 ? 136.108 120.260 126.013 1.00 40.99  ? 760 ARG A N   1 
ATOM   5592 C  CA  . ARG A 1 760 ? 135.371 121.503 125.820 1.00 40.99  ? 760 ARG A CA  1 
ATOM   5593 C  C   . ARG A 1 760 ? 135.938 122.304 124.652 1.00 40.99  ? 760 ARG A C   1 
ATOM   5594 O  O   . ARG A 1 760 ? 135.210 122.679 123.719 1.00 40.99  ? 760 ARG A O   1 
ATOM   5595 C  CB  . ARG A 1 760 ? 135.450 122.302 127.125 1.00 40.99  ? 760 ARG A CB  1 
ATOM   5596 C  CG  . ARG A 1 760 ? 134.304 123.238 127.445 1.00 40.99  ? 760 ARG A CG  1 
ATOM   5597 C  CD  . ARG A 1 760 ? 134.237 123.551 128.927 1.00 40.99  ? 760 ARG A CD  1 
ATOM   5598 N  NE  . ARG A 1 760 ? 134.348 122.345 129.740 1.00 40.99  ? 760 ARG A NE  1 
ATOM   5599 C  CZ  . ARG A 1 760 ? 133.337 121.537 130.029 1.00 40.99  ? 760 ARG A CZ  1 
ATOM   5600 N  NH1 . ARG A 1 760 ? 132.115 121.767 129.576 1.00 40.99  ? 760 ARG A NH1 1 
ATOM   5601 N  NH2 . ARG A 1 760 ? 133.558 120.470 130.791 1.00 40.99  ? 760 ARG A NH2 1 
ATOM   5602 N  N   . GLY A 1 761 ? 137.252 122.539 124.674 1.00 38.12  ? 761 GLY A N   1 
ATOM   5603 C  CA  . GLY A 1 761 ? 137.885 123.331 123.635 1.00 38.12  ? 761 GLY A CA  1 
ATOM   5604 C  C   . GLY A 1 761 ? 137.880 122.654 122.280 1.00 38.12  ? 761 GLY A C   1 
ATOM   5605 O  O   . GLY A 1 761 ? 137.638 123.303 121.261 1.00 38.12  ? 761 GLY A O   1 
ATOM   5606 N  N   . VAL A 1 762 ? 138.134 121.343 122.247 1.00 38.77  ? 762 VAL A N   1 
ATOM   5607 C  CA  . VAL A 1 762 ? 138.145 120.617 120.984 1.00 38.77  ? 762 VAL A CA  1 
ATOM   5608 C  C   . VAL A 1 762 ? 136.760 120.624 120.354 1.00 38.77  ? 762 VAL A C   1 
ATOM   5609 O  O   . VAL A 1 762 ? 136.620 120.794 119.139 1.00 38.77  ? 762 VAL A O   1 
ATOM   5610 C  CB  . VAL A 1 762 ? 138.678 119.187 121.206 1.00 38.77  ? 762 VAL A CB  1 
ATOM   5611 C  CG1 . VAL A 1 762 ? 138.595 118.348 119.938 1.00 38.77  ? 762 VAL A CG1 1 
ATOM   5612 C  CG2 . VAL A 1 762 ? 140.107 119.242 121.714 1.00 38.77  ? 762 VAL A CG2 1 
ATOM   5613 N  N   . LEU A 1 763 ? 135.734 120.439 121.188 1.00 39.92  ? 763 LEU A N   1 
ATOM   5614 C  CA  . LEU A 1 763 ? 134.337 120.419 120.678 1.00 39.92  ? 763 LEU A CA  1 
ATOM   5615 C  C   . LEU A 1 763 ? 133.998 121.795 120.110 1.00 39.92  ? 763 LEU A C   1 
ATOM   5616 O  O   . LEU A 1 763 ? 133.552 121.866 118.957 1.00 39.92  ? 763 LEU A O   1 
ATOM   5617 C  CB  . LEU A 1 763 ? 133.387 120.074 121.825 1.00 39.92  ? 763 LEU A CB  1 
ATOM   5618 C  CG  . LEU A 1 763 ? 131.900 120.084 121.475 1.00 39.92  ? 763 LEU A CG  1 
ATOM   5619 C  CD1 . LEU A 1 763 ? 131.585 119.026 120.429 1.00 39.92  ? 763 LEU A CD1 1 
ATOM   5620 C  CD2 . LEU A 1 763 ? 131.049 119.869 122.715 1.00 39.92  ? 763 LEU A CD2 1 
ATOM   5621 N  N   . ILE A 1 764 ? 134.190 122.845 120.903 1.00 35.78  ? 764 ILE A N   1 
ATOM   5622 C  CA  . ILE A 1 764 ? 133.802 124.180 120.437 1.00 35.78  ? 764 ILE A CA  1 
ATOM   5623 C  C   . ILE A 1 764 ? 134.607 124.571 119.196 1.00 35.78  ? 764 ILE A C   1 
ATOM   5624 O  O   . ILE A 1 764 ? 134.068 125.184 118.261 1.00 35.78  ? 764 ILE A O   1 
ATOM   5625 C  CB  . ILE A 1 764 ? 133.921 125.231 121.568 1.00 35.78  ? 764 ILE A CB  1 
ATOM   5626 C  CG1 . ILE A 1 764 ? 133.406 126.594 121.104 1.00 35.78  ? 764 ILE A CG1 1 
ATOM   5627 C  CG2 . ILE A 1 764 ? 135.353 125.415 122.039 1.00 35.78  ? 764 ILE A CG2 1 
ATOM   5628 C  CD1 . ILE A 1 764 ? 133.267 127.598 122.233 1.00 35.78  ? 764 ILE A CD1 1 
ATOM   5629 N  N   . GLY A 1 765 ? 135.886 124.186 119.139 1.00 36.80  ? 765 GLY A N   1 
ATOM   5630 C  CA  . GLY A 1 765 ? 136.660 124.410 117.932 1.00 36.80  ? 765 GLY A CA  1 
ATOM   5631 C  C   . GLY A 1 765 ? 136.144 123.605 116.756 1.00 36.80  ? 765 GLY A C   1 
ATOM   5632 O  O   . GLY A 1 765 ? 136.200 124.063 115.618 1.00 36.80  ? 765 GLY A O   1 
ATOM   5633 N  N   . ILE A 1 766 ? 135.636 122.398 117.016 1.00 35.55  ? 766 ILE A N   1 
ATOM   5634 C  CA  . ILE A 1 766 ? 135.021 121.592 115.965 1.00 35.55  ? 766 ILE A CA  1 
ATOM   5635 C  C   . ILE A 1 766 ? 133.782 122.292 115.420 1.00 35.55  ? 766 ILE A C   1 
ATOM   5636 O  O   . ILE A 1 766 ? 133.545 122.313 114.205 1.00 35.55  ? 766 ILE A O   1 
ATOM   5637 C  CB  . ILE A 1 766 ? 134.703 120.183 116.504 1.00 35.55  ? 766 ILE A CB  1 
ATOM   5638 C  CG1 . ILE A 1 766 ? 135.900 119.255 116.294 1.00 35.55  ? 766 ILE A CG1 1 
ATOM   5639 C  CG2 . ILE A 1 766 ? 133.459 119.593 115.853 1.00 35.55  ? 766 ILE A CG2 1 
ATOM   5640 C  CD1 . ILE A 1 766 ? 135.709 117.873 116.877 1.00 35.55  ? 766 ILE A CD1 1 
ATOM   5641 N  N   . ALA A 1 767 ? 132.984 122.887 116.310 1.00 30.57  ? 767 ALA A N   1 
ATOM   5642 C  CA  . ALA A 1 767 ? 131.824 123.659 115.870 1.00 30.57  ? 767 ALA A CA  1 
ATOM   5643 C  C   . ALA A 1 767 ? 132.245 124.834 114.992 1.00 30.57  ? 767 ALA A C   1 
ATOM   5644 O  O   . ALA A 1 767 ? 131.646 125.084 113.936 1.00 30.57  ? 767 ALA A O   1 
ATOM   5645 C  CB  . ALA A 1 767 ? 131.030 124.149 117.080 1.00 30.57  ? 767 ALA A CB  1 
ATOM   5646 N  N   . VAL A 1 768 ? 133.296 125.551 115.401 1.00 29.80  ? 768 VAL A N   1 
ATOM   5647 C  CA  . VAL A 1 768 ? 133.759 126.693 114.612 1.00 29.80  ? 768 VAL A CA  1 
ATOM   5648 C  C   . VAL A 1 768 ? 134.335 126.232 113.274 1.00 29.80  ? 768 VAL A C   1 
ATOM   5649 O  O   . VAL A 1 768 ? 134.146 126.889 112.244 1.00 29.80  ? 768 VAL A O   1 
ATOM   5650 C  CB  . VAL A 1 768 ? 134.775 127.526 115.414 1.00 29.80  ? 768 VAL A CB  1 
ATOM   5651 C  CG1 . VAL A 1 768 ? 135.236 128.728 114.606 1.00 29.80  ? 768 VAL A CG1 1 
ATOM   5652 C  CG2 . VAL A 1 768 ? 134.161 127.987 116.718 1.00 29.80  ? 768 VAL A CG2 1 
ATOM   5653 N  N   . ILE A 1 769 ? 135.032 125.094 113.265 1.00 32.18  ? 769 ILE A N   1 
ATOM   5654 C  CA  . ILE A 1 769 ? 135.608 124.556 112.033 1.00 32.18  ? 769 ILE A CA  1 
ATOM   5655 C  C   . ILE A 1 769 ? 134.505 124.167 111.058 1.00 32.18  ? 769 ILE A C   1 
ATOM   5656 O  O   . ILE A 1 769 ? 134.586 124.444 109.855 1.00 32.18  ? 769 ILE A O   1 
ATOM   5657 C  CB  . ILE A 1 769 ? 136.519 123.357 112.356 1.00 32.18  ? 769 ILE A CB  1 
ATOM   5658 C  CG1 . ILE A 1 769 ? 137.840 123.825 112.961 1.00 32.18  ? 769 ILE A CG1 1 
ATOM   5659 C  CG2 . ILE A 1 769 ? 136.796 122.525 111.112 1.00 32.18  ? 769 ILE A CG2 1 
ATOM   5660 C  CD1 . ILE A 1 769 ? 138.606 122.703 113.616 1.00 32.18  ? 769 ILE A CD1 1 
ATOM   5661 N  N   . ILE A 1 770 ? 133.456 123.517 111.566 1.00 34.77  ? 770 ILE A N   1 
ATOM   5662 C  CA  . ILE A 1 770 ? 132.338 123.122 110.717 1.00 34.77  ? 770 ILE A CA  1 
ATOM   5663 C  C   . ILE A 1 770 ? 131.619 124.352 110.174 1.00 34.77  ? 770 ILE A C   1 
ATOM   5664 O  O   . ILE A 1 770 ? 131.228 124.390 109.001 1.00 34.77  ? 770 ILE A O   1 
ATOM   5665 C  CB  . ILE A 1 770 ? 131.389 122.187 111.490 1.00 34.77  ? 770 ILE A CB  1 
ATOM   5666 C  CG1 . ILE A 1 770 ? 132.066 120.838 111.732 1.00 34.77  ? 770 ILE A CG1 1 
ATOM   5667 C  CG2 . ILE A 1 770 ? 130.089 121.975 110.733 1.00 34.77  ? 770 ILE A CG2 1 
ATOM   5668 C  CD1 . ILE A 1 770 ? 132.440 120.108 110.463 1.00 34.77  ? 770 ILE A CD1 1 
ATOM   5669 N  N   . SER A 1 771 ? 131.452 125.384 111.007 1.00 33.12  ? 771 SER A N   1 
ATOM   5670 C  CA  . SER A 1 771 ? 130.840 126.621 110.528 1.00 33.12  ? 771 SER A CA  1 
ATOM   5671 C  C   . SER A 1 771 ? 131.696 127.286 109.456 1.00 33.12  ? 771 SER A C   1 
ATOM   5672 O  O   . SER A 1 771 ? 131.170 127.810 108.467 1.00 33.12  ? 771 SER A O   1 
ATOM   5673 C  CB  . SER A 1 771 ? 130.608 127.578 111.694 1.00 33.12  ? 771 SER A CB  1 
ATOM   5674 O  OG  . SER A 1 771 ? 130.107 128.821 111.236 1.00 33.12  ? 771 SER A OG  1 
ATOM   5675 N  N   . GLN A 1 772 ? 133.018 127.266 109.633 1.00 36.07  ? 772 GLN A N   1 
ATOM   5676 C  CA  . GLN A 1 772 ? 133.921 127.818 108.628 1.00 36.07  ? 772 GLN A CA  1 
ATOM   5677 C  C   . GLN A 1 772 ? 133.837 127.039 107.321 1.00 36.07  ? 772 GLN A C   1 
ATOM   5678 O  O   . GLN A 1 772 ? 133.864 127.629 106.235 1.00 36.07  ? 772 GLN A O   1 
ATOM   5679 C  CB  . GLN A 1 772 ? 135.353 127.816 109.164 1.00 36.07  ? 772 GLN A CB  1 
ATOM   5680 C  CG  . GLN A 1 772 ? 136.354 128.536 108.284 1.00 36.07  ? 772 GLN A CG  1 
ATOM   5681 C  CD  . GLN A 1 772 ? 137.679 128.766 108.980 1.00 36.07  ? 772 GLN A CD  1 
ATOM   5682 O  OE1 . GLN A 1 772 ? 138.041 128.040 109.905 1.00 36.07  ? 772 GLN A OE1 1 
ATOM   5683 N  NE2 . GLN A 1 772 ? 138.410 129.782 108.538 1.00 36.07  ? 772 GLN A NE2 1 
ATOM   5684 N  N   . TYR A 1 773 ? 133.744 125.711 107.408 1.00 36.65  ? 773 TYR A N   1 
ATOM   5685 C  CA  . TYR A 1 773 ? 133.632 124.889 106.207 1.00 36.65  ? 773 TYR A CA  1 
ATOM   5686 C  C   . TYR A 1 773 ? 132.314 125.139 105.485 1.00 36.65  ? 773 TYR A C   1 
ATOM   5687 O  O   . TYR A 1 773 ? 132.275 125.175 104.250 1.00 36.65  ? 773 TYR A O   1 
ATOM   5688 C  CB  . TYR A 1 773 ? 133.774 123.411 106.568 1.00 36.65  ? 773 TYR A CB  1 
ATOM   5689 C  CG  . TYR A 1 773 ? 133.411 122.464 105.446 1.00 36.65  ? 773 TYR A CG  1 
ATOM   5690 C  CD1 . TYR A 1 773 ? 134.073 122.517 104.225 1.00 36.65  ? 773 TYR A CD1 1 
ATOM   5691 C  CD2 . TYR A 1 773 ? 132.408 121.518 105.607 1.00 36.65  ? 773 TYR A CD2 1 
ATOM   5692 C  CE1 . TYR A 1 773 ? 133.744 121.654 103.196 1.00 36.65  ? 773 TYR A CE1 1 
ATOM   5693 C  CE2 . TYR A 1 773 ? 132.073 120.650 104.585 1.00 36.65  ? 773 TYR A CE2 1 
ATOM   5694 C  CZ  . TYR A 1 773 ? 132.744 120.723 103.382 1.00 36.65  ? 773 TYR A CZ  1 
ATOM   5695 O  OH  . TYR A 1 773 ? 132.412 119.860 102.362 1.00 36.65  ? 773 TYR A OH  1 
ATOM   5696 N  N   . ILE A 1 774 ? 131.223 125.300 106.237 1.00 36.79  ? 774 ILE A N   1 
ATOM   5697 C  CA  . ILE A 1 774 ? 129.935 125.603 105.622 1.00 36.79  ? 774 ILE A CA  1 
ATOM   5698 C  C   . ILE A 1 774 ? 129.967 126.979 104.968 1.00 36.79  ? 774 ILE A C   1 
ATOM   5699 O  O   . ILE A 1 774 ? 129.447 127.168 103.861 1.00 36.79  ? 774 ILE A O   1 
ATOM   5700 C  CB  . ILE A 1 774 ? 128.805 125.483 106.663 1.00 36.79  ? 774 ILE A CB  1 
ATOM   5701 C  CG1 . ILE A 1 774 ? 128.639 124.027 107.097 1.00 36.79  ? 774 ILE A CG1 1 
ATOM   5702 C  CG2 . ILE A 1 774 ? 127.491 125.996 106.101 1.00 36.79  ? 774 ILE A CG2 1 
ATOM   5703 C  CD1 . ILE A 1 774 ? 128.256 123.093 105.969 1.00 36.79  ? 774 ILE A CD1 1 
ATOM   5704 N  N   . GLY A 1 775 ? 130.591 127.957 105.629 1.00 40.66  ? 775 GLY A N   1 
ATOM   5705 C  CA  . GLY A 1 775 ? 130.738 129.270 105.026 1.00 40.66  ? 775 GLY A CA  1 
ATOM   5706 C  C   . GLY A 1 775 ? 131.632 129.270 103.801 1.00 40.66  ? 775 GLY A C   1 
ATOM   5707 O  O   . GLY A 1 775 ? 131.465 130.104 102.908 1.00 40.66  ? 775 GLY A O   1 
ATOM   5708 N  N   . MET A 1 776 ? 132.591 128.339 103.743 1.00 43.22  ? 776 MET A N   1 
ATOM   5709 C  CA  . MET A 1 776 ? 133.444 128.212 102.564 1.00 43.22  ? 776 MET A CA  1 
ATOM   5710 C  C   . MET A 1 776 ? 132.633 127.834 101.331 1.00 43.22  ? 776 MET A C   1 
ATOM   5711 O  O   . MET A 1 776 ? 133.004 128.192 100.207 1.00 43.22  ? 776 MET A O   1 
ATOM   5712 C  CB  . MET A 1 776 ? 134.544 127.176 102.829 1.00 43.22  ? 776 MET A CB  1 
ATOM   5713 C  CG  . MET A 1 776 ? 135.534 126.965 101.685 1.00 43.22  ? 776 MET A CG  1 
ATOM   5714 S  SD  . MET A 1 776 ? 135.102 125.586 100.601 1.00 43.22  ? 776 MET A SD  1 
ATOM   5715 C  CE  . MET A 1 776 ? 136.236 124.324 101.170 1.00 43.22  ? 776 MET A CE  1 
ATOM   5716 N  N   . GLN A 1 777 ? 131.514 127.132 101.523 1.00 44.61  ? 777 GLN A N   1 
ATOM   5717 C  CA  . GLN A 1 777 ? 130.635 126.793 100.412 1.00 44.61  ? 777 GLN A CA  1 
ATOM   5718 C  C   . GLN A 1 777 ? 129.969 128.020 99.802  1.00 44.61  ? 777 GLN A C   1 
ATOM   5719 O  O   . GLN A 1 777 ? 129.465 127.940 98.677  1.00 44.61  ? 777 GLN A O   1 
ATOM   5720 C  CB  . GLN A 1 777 ? 129.569 125.798 100.875 1.00 44.61  ? 777 GLN A CB  1 
ATOM   5721 C  CG  . GLN A 1 777 ? 130.075 124.373 101.033 1.00 44.61  ? 777 GLN A CG  1 
ATOM   5722 C  CD  . GLN A 1 777 ? 128.995 123.420 101.505 1.00 44.61  ? 777 GLN A CD  1 
ATOM   5723 O  OE1 . GLN A 1 777 ? 127.972 123.840 102.045 1.00 44.61  ? 777 GLN A OE1 1 
ATOM   5724 N  NE2 . GLN A 1 777 ? 129.219 122.126 101.306 1.00 44.61  ? 777 GLN A NE2 1 
ATOM   5725 N  N   . ILE A 1 778 ? 129.952 129.149 100.513 1.00 45.25  ? 778 ILE A N   1 
ATOM   5726 C  CA  . ILE A 1 778 ? 129.352 130.371 99.992  1.00 45.25  ? 778 ILE A CA  1 
ATOM   5727 C  C   . ILE A 1 778 ? 130.441 131.340 99.551  1.00 45.25  ? 778 ILE A C   1 
ATOM   5728 O  O   . ILE A 1 778 ? 130.563 131.651 98.361  1.00 45.25  ? 778 ILE A O   1 
ATOM   5729 C  CB  . ILE A 1 778 ? 128.431 131.023 101.038 1.00 45.25  ? 778 ILE A CB  1 
ATOM   5730 C  CG1 . ILE A 1 778 ? 127.342 130.042 101.475 1.00 45.25  ? 778 ILE A CG1 1 
ATOM   5731 C  CG2 . ILE A 1 778 ? 127.808 132.290 100.476 1.00 45.25  ? 778 ILE A CG2 1 
ATOM   5732 C  CD1 . ILE A 1 778 ? 126.412 130.593 102.535 1.00 45.25  ? 778 ILE A CD1 1 
ATOM   5733 N  N   . SER A 1 779 ? 131.257 131.803 100.505 1.00 38.51  ? 779 SER A N   1 
ATOM   5734 C  CA  . SER A 1 779 ? 132.301 132.792 100.253 1.00 38.51  ? 779 SER A CA  1 
ATOM   5735 C  C   . SER A 1 779 ? 133.228 132.901 101.460 1.00 38.51  ? 779 SER A C   1 
ATOM   5736 O  O   . SER A 1 779 ? 132.815 132.586 102.584 1.00 38.51  ? 779 SER A O   1 
ATOM   5737 C  CB  . SER A 1 779 ? 131.686 134.158 99.930  1.00 38.51  ? 779 SER A CB  1 
ATOM   5738 O  OG  . SER A 1 779 ? 130.534 134.403 100.717 1.00 38.51  ? 779 SER A OG  1 
ATOM   5739 N  N   . PRO A 1 780 ? 134.487 133.318 101.269 1.00 36.40  ? 780 PRO A N   1 
ATOM   5740 C  CA  . PRO A 1 780 ? 135.381 133.496 102.429 1.00 36.40  ? 780 PRO A CA  1 
ATOM   5741 C  C   . PRO A 1 780 ? 134.886 134.518 103.439 1.00 36.40  ? 780 PRO A C   1 
ATOM   5742 O  O   . PRO A 1 780 ? 135.095 134.340 104.645 1.00 36.40  ? 780 PRO A O   1 
ATOM   5743 C  CB  . PRO A 1 780 ? 136.703 133.934 101.782 1.00 36.40  ? 780 PRO A CB  1 
ATOM   5744 C  CG  . PRO A 1 780 ? 136.641 133.399 100.396 1.00 36.40  ? 780 PRO A CG  1 
ATOM   5745 C  CD  . PRO A 1 780 ? 135.201 133.486 99.992  1.00 36.40  ? 780 PRO A CD  1 
ATOM   5746 N  N   . GLU A 1 781 ? 134.241 135.592 102.977 1.00 39.69  ? 781 GLU A N   1 
ATOM   5747 C  CA  . GLU A 1 781 ? 133.657 136.560 103.900 1.00 39.69  ? 781 GLU A CA  1 
ATOM   5748 C  C   . GLU A 1 781 ? 132.532 135.933 104.715 1.00 39.69  ? 781 GLU A C   1 
ATOM   5749 O  O   . GLU A 1 781 ? 132.431 136.159 105.930 1.00 39.69  ? 781 GLU A O   1 
ATOM   5750 C  CB  . GLU A 1 781 ? 133.149 137.775 103.125 1.00 39.69  ? 781 GLU A CB  1 
ATOM   5751 C  CG  . GLU A 1 781 ? 134.216 138.807 102.805 1.00 39.69  ? 781 GLU A CG  1 
ATOM   5752 C  CD  . GLU A 1 781 ? 134.538 139.699 103.987 1.00 39.69  ? 781 GLU A CD  1 
ATOM   5753 O  OE1 . GLU A 1 781 ? 133.756 139.705 104.961 1.00 39.69  ? 781 GLU A OE1 1 
ATOM   5754 O  OE2 . GLU A 1 781 ? 135.573 140.396 103.942 1.00 39.69  ? 781 GLU A OE2 1 
ATOM   5755 N  N   . MET A 1 782 ? 131.682 135.136 104.060 1.00 40.77  ? 782 MET A N   1 
ATOM   5756 C  CA  . MET A 1 782 ? 130.639 134.407 104.772 1.00 40.77  ? 782 MET A CA  1 
ATOM   5757 C  C   . MET A 1 782 ? 131.243 133.418 105.756 1.00 40.77  ? 782 MET A C   1 
ATOM   5758 O  O   . MET A 1 782 ? 130.718 133.230 106.858 1.00 40.77  ? 782 MET A O   1 
ATOM   5759 C  CB  . MET A 1 782 ? 129.735 133.677 103.781 1.00 40.77  ? 782 MET A CB  1 
ATOM   5760 C  CG  . MET A 1 782 ? 128.465 134.420 103.422 1.00 40.77  ? 782 MET A CG  1 
ATOM   5761 S  SD  . MET A 1 782 ? 127.729 135.294 104.812 1.00 40.77  ? 782 MET A SD  1 
ATOM   5762 C  CE  . MET A 1 782 ? 127.027 136.700 103.957 1.00 40.77  ? 782 MET A CE  1 
ATOM   5763 N  N   . SER A 1 783 ? 132.350 132.777 105.370 1.00 38.58  ? 783 SER A N   1 
ATOM   5764 C  CA  . SER A 1 783 ? 133.038 131.860 106.272 1.00 38.58  ? 783 SER A CA  1 
ATOM   5765 C  C   . SER A 1 783 ? 133.547 132.581 107.513 1.00 38.58  ? 783 SER A C   1 
ATOM   5766 O  O   . SER A 1 783 ? 133.382 132.088 108.635 1.00 38.58  ? 783 SER A O   1 
ATOM   5767 C  CB  . SER A 1 783 ? 134.191 131.179 105.537 1.00 38.58  ? 783 SER A CB  1 
ATOM   5768 O  OG  . SER A 1 783 ? 135.272 130.924 106.414 1.00 38.58  ? 783 SER A OG  1 
ATOM   5769 N  N   . VAL A 1 784 ? 134.147 133.760 107.330 1.00 36.16  ? 784 VAL A N   1 
ATOM   5770 C  CA  . VAL A 1 784 ? 134.660 134.533 108.460 1.00 36.16  ? 784 VAL A CA  1 
ATOM   5771 C  C   . VAL A 1 784 ? 133.519 134.942 109.383 1.00 36.16  ? 784 VAL A C   1 
ATOM   5772 O  O   . VAL A 1 784 ? 133.594 134.774 110.610 1.00 36.16  ? 784 VAL A O   1 
ATOM   5773 C  CB  . VAL A 1 784 ? 135.448 135.756 107.951 1.00 36.16  ? 784 VAL A CB  1 
ATOM   5774 C  CG1 . VAL A 1 784 ? 135.405 136.903 108.953 1.00 36.16  ? 784 VAL A CG1 1 
ATOM   5775 C  CG2 . VAL A 1 784 ? 136.879 135.373 107.638 1.00 36.16  ? 784 VAL A CG2 1 
ATOM   5776 N  N   . ALA A 1 785 ? 132.431 135.456 108.800 1.00 37.67  ? 785 ALA A N   1 
ATOM   5777 C  CA  . ALA A 1 785 ? 131.302 135.921 109.601 1.00 37.67  ? 785 ALA A CA  1 
ATOM   5778 C  C   . ALA A 1 785 ? 130.656 134.774 110.368 1.00 37.67  ? 785 ALA A C   1 
ATOM   5779 O  O   . ALA A 1 785 ? 130.367 134.895 111.568 1.00 37.67  ? 785 ALA A O   1 
ATOM   5780 C  CB  . ALA A 1 785 ? 130.277 136.611 108.702 1.00 37.67  ? 785 ALA A CB  1 
ATOM   5781 N  N   . MET A 1 786 ? 130.439 133.642 109.693 1.00 37.22  ? 786 MET A N   1 
ATOM   5782 C  CA  . MET A 1 786 ? 129.781 132.509 110.329 1.00 37.22  ? 786 MET A CA  1 
ATOM   5783 C  C   . MET A 1 786 ? 130.663 131.887 111.401 1.00 37.22  ? 786 MET A C   1 
ATOM   5784 O  O   . MET A 1 786 ? 130.162 131.481 112.454 1.00 37.22  ? 786 MET A O   1 
ATOM   5785 C  CB  . MET A 1 786 ? 129.386 131.473 109.278 1.00 37.22  ? 786 MET A CB  1 
ATOM   5786 C  CG  . MET A 1 786 ? 128.032 131.746 108.646 1.00 37.22  ? 786 MET A CG  1 
ATOM   5787 S  SD  . MET A 1 786 ? 127.758 130.809 107.133 1.00 37.22  ? 786 MET A SD  1 
ATOM   5788 C  CE  . MET A 1 786 ? 127.225 129.243 107.813 1.00 37.22  ? 786 MET A CE  1 
ATOM   5789 N  N   . ALA A 1 787 ? 131.977 131.818 111.166 1.00 35.28  ? 787 ALA A N   1 
ATOM   5790 C  CA  . ALA A 1 787 ? 132.879 131.308 112.191 1.00 35.28  ? 787 ALA A CA  1 
ATOM   5791 C  C   . ALA A 1 787 ? 132.891 132.213 113.414 1.00 35.28  ? 787 ALA A C   1 
ATOM   5792 O  O   . ALA A 1 787 ? 132.882 131.727 114.552 1.00 35.28  ? 787 ALA A O   1 
ATOM   5793 C  CB  . ALA A 1 787 ? 134.287 131.154 111.621 1.00 35.28  ? 787 ALA A CB  1 
ATOM   5794 N  N   . PHE A 1 788 ? 132.886 133.534 113.202 1.00 33.04  ? 788 PHE A N   1 
ATOM   5795 C  CA  . PHE A 1 788 ? 132.874 134.463 114.328 1.00 33.04  ? 788 PHE A CA  1 
ATOM   5796 C  C   . PHE A 1 788 ? 131.602 134.318 115.153 1.00 33.04  ? 788 PHE A C   1 
ATOM   5797 O  O   . PHE A 1 788 ? 131.657 134.214 116.388 1.00 33.04  ? 788 PHE A O   1 
ATOM   5798 C  CB  . PHE A 1 788 ? 133.023 135.898 113.825 1.00 33.04  ? 788 PHE A CB  1 
ATOM   5799 C  CG  . PHE A 1 788 ? 132.411 136.929 114.735 1.00 33.04  ? 788 PHE A CG  1 
ATOM   5800 C  CD1 . PHE A 1 788 ? 132.997 137.238 115.951 1.00 33.04  ? 788 PHE A CD1 1 
ATOM   5801 C  CD2 . PHE A 1 788 ? 131.249 137.591 114.372 1.00 33.04  ? 788 PHE A CD2 1 
ATOM   5802 C  CE1 . PHE A 1 788 ? 132.437 138.184 116.788 1.00 33.04  ? 788 PHE A CE1 1 
ATOM   5803 C  CE2 . PHE A 1 788 ? 130.684 138.538 115.205 1.00 33.04  ? 788 PHE A CE2 1 
ATOM   5804 C  CZ  . PHE A 1 788 ? 131.279 138.834 116.414 1.00 33.04  ? 788 PHE A CZ  1 
ATOM   5805 N  N   . THR A 1 789 ? 130.439 134.308 114.489 1.00 28.33  ? 789 THR A N   1 
ATOM   5806 C  CA  . THR A 1 789 ? 129.198 134.221 115.253 1.00 28.33  ? 789 THR A CA  1 
ATOM   5807 C  C   . THR A 1 789 ? 129.036 132.852 115.901 1.00 28.33  ? 789 THR A C   1 
ATOM   5808 O  O   . THR A 1 789 ? 128.522 132.764 117.023 1.00 28.33  ? 789 THR A O   1 
ATOM   5809 C  CB  . THR A 1 789 ? 127.978 134.567 114.391 1.00 28.33  ? 789 THR A CB  1 
ATOM   5810 O  OG1 . THR A 1 789 ? 126.786 134.388 115.166 1.00 28.33  ? 789 THR A OG1 1 
ATOM   5811 C  CG2 . THR A 1 789 ? 127.887 133.696 113.169 1.00 28.33  ? 789 THR A CG2 1 
ATOM   5812 N  N   . THR A 1 790 ? 129.506 131.786 115.243 1.00 29.59  ? 790 THR A N   1 
ATOM   5813 C  CA  . THR A 1 790 ? 129.478 130.463 115.851 1.00 29.59  ? 790 THR A CA  1 
ATOM   5814 C  C   . THR A 1 790 ? 130.335 130.423 117.107 1.00 29.59  ? 790 THR A C   1 
ATOM   5815 O  O   . THR A 1 790 ? 129.895 129.915 118.144 1.00 29.59  ? 790 THR A O   1 
ATOM   5816 C  CB  . THR A 1 790 ? 129.946 129.415 114.839 1.00 29.59  ? 790 THR A CB  1 
ATOM   5817 O  OG1 . THR A 1 790 ? 128.859 129.067 113.976 1.00 29.59  ? 790 THR A OG1 1 
ATOM   5818 C  CG2 . THR A 1 790 ? 130.444 128.154 115.534 1.00 29.59  ? 790 THR A CG2 1 
ATOM   5819 N  N   . LEU A 1 791 ? 131.542 130.995 117.049 1.00 70.04  ? 791 LEU A N   1 
ATOM   5820 C  CA  . LEU A 1 791 ? 132.415 130.979 118.218 1.00 70.04  ? 791 LEU A CA  1 
ATOM   5821 C  C   . LEU A 1 791 ? 131.818 131.777 119.369 1.00 70.04  ? 791 LEU A C   1 
ATOM   5822 O  O   . LEU A 1 791 ? 131.800 131.307 120.511 1.00 70.04  ? 791 LEU A O   1 
ATOM   5823 C  CB  . LEU A 1 791 ? 133.802 131.514 117.866 1.00 70.04  ? 791 LEU A CB  1 
ATOM   5824 C  CG  . LEU A 1 791 ? 134.733 131.555 119.083 1.00 70.04  ? 791 LEU A CG  1 
ATOM   5825 C  CD1 . LEU A 1 791 ? 134.963 130.156 119.632 1.00 70.04  ? 791 LEU A CD1 1 
ATOM   5826 C  CD2 . LEU A 1 791 ? 136.053 132.219 118.763 1.00 70.04  ? 791 LEU A CD2 1 
ATOM   5827 N  N   . ILE A 1 792 ? 131.306 132.980 119.092 1.00 32.45  ? 792 ILE A N   1 
ATOM   5828 C  CA  . ILE A 1 792 ? 130.824 133.809 120.197 1.00 32.45  ? 792 ILE A CA  1 
ATOM   5829 C  C   . ILE A 1 792 ? 129.539 133.231 120.793 1.00 32.45  ? 792 ILE A C   1 
ATOM   5830 O  O   . ILE A 1 792 ? 129.362 133.217 122.021 1.00 32.45  ? 792 ILE A O   1 
ATOM   5831 C  CB  . ILE A 1 792 ? 130.666 135.280 119.759 1.00 32.45  ? 792 ILE A CB  1 
ATOM   5832 C  CG1 . ILE A 1 792 ? 130.262 136.153 120.946 1.00 32.45  ? 792 ILE A CG1 1 
ATOM   5833 C  CG2 . ILE A 1 792 ? 129.661 135.440 118.638 1.00 32.45  ? 792 ILE A CG2 1 
ATOM   5834 C  CD1 . ILE A 1 792 ? 130.174 137.617 120.605 1.00 32.45  ? 792 ILE A CD1 1 
ATOM   5835 N  N   . LEU A 1 793 ? 128.640 132.707 119.949 1.00 35.04  ? 793 LEU A N   1 
ATOM   5836 C  CA  . LEU A 1 793 ? 127.427 132.084 120.465 1.00 35.04  ? 793 LEU A CA  1 
ATOM   5837 C  C   . LEU A 1 793 ? 127.748 130.815 121.241 1.00 35.04  ? 793 LEU A C   1 
ATOM   5838 O  O   . LEU A 1 793 ? 127.135 130.547 122.281 1.00 35.04  ? 793 LEU A O   1 
ATOM   5839 C  CB  . LEU A 1 793 ? 126.461 131.784 119.320 1.00 35.04  ? 793 LEU A CB  1 
ATOM   5840 C  CG  . LEU A 1 793 ? 125.019 132.250 119.528 1.00 35.04  ? 793 LEU A CG  1 
ATOM   5841 C  CD1 . LEU A 1 793 ? 124.988 133.673 120.060 1.00 35.04  ? 793 LEU A CD1 1 
ATOM   5842 C  CD2 . LEU A 1 793 ? 124.228 132.139 118.236 1.00 35.04  ? 793 LEU A CD2 1 
ATOM   5843 N  N   . ALA A 1 794 ? 128.716 130.028 120.763 1.00 34.83  ? 794 ALA A N   1 
ATOM   5844 C  CA  . ALA A 1 794 ? 129.104 128.821 121.476 1.00 34.83  ? 794 ALA A CA  1 
ATOM   5845 C  C   . ALA A 1 794 ? 129.776 129.146 122.800 1.00 34.83  ? 794 ALA A C   1 
ATOM   5846 O  O   . ALA A 1 794 ? 129.598 128.408 123.767 1.00 34.83  ? 794 ALA A O   1 
ATOM   5847 C  CB  . ALA A 1 794 ? 130.016 127.967 120.600 1.00 34.83  ? 794 ALA A CB  1 
ATOM   5848 N  N   . ARG A 1 795 ? 130.525 130.248 122.874 1.00 33.93  ? 795 ARG A N   1 
ATOM   5849 C  CA  . ARG A 1 795 ? 131.083 130.683 124.153 1.00 33.93  ? 795 ARG A CA  1 
ATOM   5850 C  C   . ARG A 1 795 ? 129.976 131.063 125.129 1.00 33.93  ? 795 ARG A C   1 
ATOM   5851 O  O   . ARG A 1 795 ? 129.958 130.608 126.284 1.00 33.93  ? 795 ARG A O   1 
ATOM   5852 C  CB  . ARG A 1 795 ? 132.024 131.868 123.934 1.00 33.93  ? 795 ARG A CB  1 
ATOM   5853 C  CG  . ARG A 1 795 ? 133.337 131.507 123.277 1.00 33.93  ? 795 ARG A CG  1 
ATOM   5854 C  CD  . ARG A 1 795 ? 134.242 130.764 124.222 1.00 33.93  ? 795 ARG A CD  1 
ATOM   5855 N  NE  . ARG A 1 795 ? 135.002 131.658 125.087 1.00 33.93  ? 795 ARG A NE  1 
ATOM   5856 C  CZ  . ARG A 1 795 ? 136.144 132.237 124.740 1.00 33.93  ? 795 ARG A CZ  1 
ATOM   5857 N  NH1 . ARG A 1 795 ? 136.672 132.060 123.540 1.00 33.93  ? 795 ARG A NH1 1 
ATOM   5858 N  NH2 . ARG A 1 795 ? 136.774 133.010 125.619 1.00 33.93  ? 795 ARG A NH2 1 
ATOM   5859 N  N   . THR A 1 796 ? 129.032 131.891 124.669 1.00 34.66  ? 796 THR A N   1 
ATOM   5860 C  CA  . THR A 1 796 ? 127.969 132.367 125.547 1.00 34.66  ? 796 THR A CA  1 
ATOM   5861 C  C   . THR A 1 796 ? 127.076 131.222 126.016 1.00 34.66  ? 796 THR A C   1 
ATOM   5862 O  O   . THR A 1 796 ? 126.601 131.226 127.157 1.00 34.66  ? 796 THR A O   1 
ATOM   5863 C  CB  . THR A 1 796 ? 127.143 133.440 124.837 1.00 34.66  ? 796 THR A CB  1 
ATOM   5864 O  OG1 . THR A 1 796 ? 128.023 134.365 124.187 1.00 34.66  ? 796 THR A OG1 1 
ATOM   5865 C  CG2 . THR A 1 796 ? 126.284 134.199 125.836 1.00 34.66  ? 796 THR A CG2 1 
ATOM   5866 N  N   . LEU A 1 797 ? 126.848 130.224 125.160 1.00 34.77  ? 797 LEU A N   1 
ATOM   5867 C  CA  . LEU A 1 797 ? 126.011 129.098 125.554 1.00 34.77  ? 797 LEU A CA  1 
ATOM   5868 C  C   . LEU A 1 797 ? 126.788 127.986 126.246 1.00 34.77  ? 797 LEU A C   1 
ATOM   5869 O  O   . LEU A 1 797 ? 126.176 127.154 126.923 1.00 34.77  ? 797 LEU A O   1 
ATOM   5870 C  CB  . LEU A 1 797 ? 125.278 128.541 124.334 1.00 34.77  ? 797 LEU A CB  1 
ATOM   5871 C  CG  . LEU A 1 797 ? 124.329 129.532 123.659 1.00 34.77  ? 797 LEU A CG  1 
ATOM   5872 C  CD1 . LEU A 1 797 ? 123.691 128.910 122.432 1.00 34.77  ? 797 LEU A CD1 1 
ATOM   5873 C  CD2 . LEU A 1 797 ? 123.267 130.013 124.636 1.00 34.77  ? 797 LEU A CD2 1 
ATOM   5874 N  N   . GLN A 1 798 ? 128.113 127.945 126.095 1.00 31.06  ? 798 GLN A N   1 
ATOM   5875 C  CA  . GLN A 1 798 ? 128.948 127.007 126.828 1.00 31.06  ? 798 GLN A CA  1 
ATOM   5876 C  C   . GLN A 1 798 ? 129.217 127.503 128.240 1.00 31.06  ? 798 GLN A C   1 
ATOM   5877 O  O   . GLN A 1 798 ? 129.581 126.706 129.113 1.00 31.06  ? 798 GLN A O   1 
ATOM   5878 C  CB  . GLN A 1 798 ? 130.241 126.774 126.028 1.00 31.06  ? 798 GLN A CB  1 
ATOM   5879 C  CG  . GLN A 1 798 ? 131.419 126.139 126.751 1.00 31.06  ? 798 GLN A CG  1 
ATOM   5880 C  CD  . GLN A 1 798 ? 132.491 127.147 127.094 1.00 31.06  ? 798 GLN A CD  1 
ATOM   5881 O  OE1 . GLN A 1 798 ? 132.421 128.303 126.682 1.00 31.06  ? 798 GLN A OE1 1 
ATOM   5882 N  NE2 . GLN A 1 798 ? 133.492 126.715 127.851 1.00 31.06  ? 798 GLN A NE2 1 
ATOM   5883 N  N   . THR A 1 799 ? 129.005 128.799 128.482 1.00 31.71  ? 799 THR A N   1 
ATOM   5884 C  CA  . THR A 1 799 ? 128.920 129.290 129.856 1.00 31.71  ? 799 THR A CA  1 
ATOM   5885 C  C   . THR A 1 799 ? 127.860 128.520 130.647 1.00 31.71  ? 799 THR A C   1 
ATOM   5886 O  O   . THR A 1 799 ? 128.050 128.224 131.834 1.00 31.71  ? 799 THR A O   1 
ATOM   5887 C  CB  . THR A 1 799 ? 128.627 130.795 129.852 1.00 31.71  ? 799 THR A CB  1 
ATOM   5888 O  OG1 . THR A 1 799 ? 129.797 131.503 129.426 1.00 31.71  ? 799 THR A OG1 1 
ATOM   5889 C  CG2 . THR A 1 799 ? 128.245 131.292 131.239 1.00 31.71  ? 799 THR A CG2 1 
ATOM   5890 N  N   . PHE A 1 800 ? 126.753 128.150 129.991 1.00 31.88  ? 800 PHE A N   1 
ATOM   5891 C  CA  . PHE A 1 800 ? 125.753 127.287 130.620 1.00 31.88  ? 800 PHE A CA  1 
ATOM   5892 C  C   . PHE A 1 800 ? 126.335 125.924 130.977 1.00 31.88  ? 800 PHE A C   1 
ATOM   5893 O  O   . PHE A 1 800 ? 126.218 125.466 132.119 1.00 31.88  ? 800 PHE A O   1 
ATOM   5894 C  CB  . PHE A 1 800 ? 124.551 127.098 129.693 1.00 31.88  ? 800 PHE A CB  1 
ATOM   5895 C  CG  . PHE A 1 800 ? 123.617 128.270 129.639 1.00 31.88  ? 800 PHE A CG  1 
ATOM   5896 C  CD1 . PHE A 1 800 ? 123.659 129.264 130.600 1.00 31.88  ? 800 PHE A CD1 1 
ATOM   5897 C  CD2 . PHE A 1 800 ? 122.677 128.363 128.624 1.00 31.88  ? 800 PHE A CD2 1 
ATOM   5898 C  CE1 . PHE A 1 800 ? 122.785 130.334 130.544 1.00 31.88  ? 800 PHE A CE1 1 
ATOM   5899 C  CE2 . PHE A 1 800 ? 121.804 129.428 128.562 1.00 31.88  ? 800 PHE A CE2 1 
ATOM   5900 C  CZ  . PHE A 1 800 ? 121.856 130.414 129.524 1.00 31.88  ? 800 PHE A CZ  1 
ATOM   5901 N  N   . ALA A 1 801 ? 126.962 125.257 130.005 1.00 37.47  ? 801 ALA A N   1 
ATOM   5902 C  CA  . ALA A 1 801 ? 127.385 123.874 130.199 1.00 37.47  ? 801 ALA A CA  1 
ATOM   5903 C  C   . ALA A 1 801 ? 128.598 123.752 131.109 1.00 37.47  ? 801 ALA A C   1 
ATOM   5904 O  O   . ALA A 1 801 ? 128.840 122.669 131.653 1.00 37.47  ? 801 ALA A O   1 
ATOM   5905 C  CB  . ALA A 1 801 ? 127.684 123.222 128.849 1.00 37.47  ? 801 ALA A CB  1 
ATOM   5906 N  N   . ALA A 1 802 ? 129.361 124.827 131.288 1.00 32.81  ? 802 ALA A N   1 
ATOM   5907 C  CA  . ALA A 1 802 ? 130.521 124.823 132.165 1.00 32.81  ? 802 ALA A CA  1 
ATOM   5908 C  C   . ALA A 1 802 ? 130.188 125.292 133.575 1.00 32.81  ? 802 ALA A C   1 
ATOM   5909 O  O   . ALA A 1 802 ? 131.086 125.738 134.298 1.00 32.81  ? 802 ALA A O   1 
ATOM   5910 C  CB  . ALA A 1 802 ? 131.635 125.687 131.572 1.00 32.81  ? 802 ALA A CB  1 
ATOM   5911 N  N   . ARG A 1 803 ? 128.918 125.205 133.979 1.00 41.80  ? 803 ARG A N   1 
ATOM   5912 C  CA  . ARG A 1 803 ? 128.548 125.610 135.330 1.00 41.80  ? 803 ARG A CA  1 
ATOM   5913 C  C   . ARG A 1 803 ? 129.060 124.624 136.369 1.00 41.80  ? 803 ARG A C   1 
ATOM   5914 O  O   . ARG A 1 803 ? 129.334 125.014 137.509 1.00 41.80  ? 803 ARG A O   1 
ATOM   5915 C  CB  . ARG A 1 803 ? 127.033 125.765 135.439 1.00 41.80  ? 803 ARG A CB  1 
ATOM   5916 C  CG  . ARG A 1 803 ? 126.533 127.133 135.016 1.00 41.80  ? 803 ARG A CG  1 
ATOM   5917 C  CD  . ARG A 1 803 ? 125.201 127.456 135.661 1.00 41.80  ? 803 ARG A CD  1 
ATOM   5918 N  NE  . ARG A 1 803 ? 124.259 126.351 135.539 1.00 41.80  ? 803 ARG A NE  1 
ATOM   5919 C  CZ  . ARG A 1 803 ? 122.957 126.451 135.765 1.00 41.80  ? 803 ARG A CZ  1 
ATOM   5920 N  NH1 . ARG A 1 803 ? 122.403 127.600 136.114 1.00 41.80  ? 803 ARG A NH1 1 
ATOM   5921 N  NH2 . ARG A 1 803 ? 122.193 125.371 135.640 1.00 41.80  ? 803 ARG A NH2 1 
ATOM   5922 N  N   . SER A 1 804 ? 129.193 123.354 135.996 1.00 42.68  ? 804 SER A N   1 
ATOM   5923 C  CA  . SER A 1 804 ? 129.780 122.345 136.864 1.00 42.68  ? 804 SER A CA  1 
ATOM   5924 C  C   . SER A 1 804 ? 130.238 121.180 136.003 1.00 42.68  ? 804 SER A C   1 
ATOM   5925 O  O   . SER A 1 804 ? 129.800 121.019 134.861 1.00 42.68  ? 804 SER A O   1 
ATOM   5926 C  CB  . SER A 1 804 ? 128.791 121.866 137.932 1.00 42.68  ? 804 SER A CB  1 
ATOM   5927 O  OG  . SER A 1 804 ? 127.680 121.218 137.340 1.00 42.68  ? 804 SER A OG  1 
ATOM   5928 N  N   . ASN A 1 805 ? 131.125 120.368 136.567 1.00 46.18  ? 805 ASN A N   1 
ATOM   5929 C  CA  . ASN A 1 805 ? 131.562 119.139 135.923 1.00 46.18  ? 805 ASN A CA  1 
ATOM   5930 C  C   . ASN A 1 805 ? 130.693 117.950 136.302 1.00 46.18  ? 805 ASN A C   1 
ATOM   5931 O  O   . ASN A 1 805 ? 130.983 116.825 135.882 1.00 46.18  ? 805 ASN A O   1 
ATOM   5932 C  CB  . ASN A 1 805 ? 133.024 118.848 136.276 1.00 46.18  ? 805 ASN A CB  1 
ATOM   5933 C  CG  . ASN A 1 805 ? 133.848 120.112 136.433 1.00 46.18  ? 805 ASN A CG  1 
ATOM   5934 O  OD1 . ASN A 1 805 ? 134.035 120.867 135.479 1.00 46.18  ? 805 ASN A OD1 1 
ATOM   5935 N  ND2 . ASN A 1 805 ? 134.346 120.347 137.641 1.00 46.18  ? 805 ASN A ND2 1 
ATOM   5936 N  N   . VAL A 1 806 ? 129.639 118.176 137.087 1.00 50.67  ? 806 VAL A N   1 
ATOM   5937 C  CA  . VAL A 1 806 ? 128.762 117.118 137.563 1.00 50.67  ? 806 VAL A CA  1 
ATOM   5938 C  C   . VAL A 1 806 ? 127.318 117.333 137.125 1.00 50.67  ? 806 VAL A C   1 
ATOM   5939 O  O   . VAL A 1 806 ? 126.670 116.403 136.632 1.00 50.67  ? 806 VAL A O   1 
ATOM   5940 C  CB  . VAL A 1 806 ? 128.857 116.982 139.102 1.00 50.67  ? 806 VAL A CB  1 
ATOM   5941 C  CG1 . VAL A 1 806 ? 127.849 115.959 139.615 1.00 50.67  ? 806 VAL A CG1 1 
ATOM   5942 C  CG2 . VAL A 1 806 ? 130.268 116.612 139.534 1.00 50.67  ? 806 VAL A CG2 1 
ATOM   5943 N  N   . GLN A 1 807 ? 126.802 118.550 137.266 1.00 49.00  ? 807 GLN A N   1 
ATOM   5944 C  CA  . GLN A 1 807 ? 125.413 118.858 136.965 1.00 49.00  ? 807 GLN A CA  1 
ATOM   5945 C  C   . GLN A 1 807 ? 125.328 119.635 135.660 1.00 49.00  ? 807 GLN A C   1 
ATOM   5946 O  O   . GLN A 1 807 ? 126.169 120.495 135.381 1.00 49.00  ? 807 GLN A O   1 
ATOM   5947 C  CB  . GLN A 1 807 ? 124.780 119.668 138.099 1.00 49.00  ? 807 GLN A CB  1 
ATOM   5948 C  CG  . GLN A 1 807 ? 124.396 118.847 139.322 1.00 49.00  ? 807 GLN A CG  1 
ATOM   5949 C  CD  . GLN A 1 807 ? 122.991 118.284 139.237 1.00 49.00  ? 807 GLN A CD  1 
ATOM   5950 O  OE1 . GLN A 1 807 ? 122.331 118.386 138.203 1.00 49.00  ? 807 GLN A OE1 1 
ATOM   5951 N  NE2 . GLN A 1 807 ? 122.526 117.689 140.329 1.00 49.00  ? 807 GLN A NE2 1 
ATOM   5952 N  N   . THR A 1 808 ? 124.307 119.332 134.865 1.00 52.61  ? 808 THR A N   1 
ATOM   5953 C  CA  . THR A 1 808 ? 124.098 120.029 133.607 1.00 52.61  ? 808 THR A CA  1 
ATOM   5954 C  C   . THR A 1 808 ? 123.450 121.387 133.865 1.00 52.61  ? 808 THR A C   1 
ATOM   5955 O  O   . THR A 1 808 ? 123.128 121.749 135.000 1.00 52.61  ? 808 THR A O   1 
ATOM   5956 C  CB  . THR A 1 808 ? 123.244 119.184 132.666 1.00 52.61  ? 808 THR A CB  1 
ATOM   5957 O  OG1 . THR A 1 808 ? 121.899 119.129 133.158 1.00 52.61  ? 808 THR A OG1 1 
ATOM   5958 C  CG2 . THR A 1 808 ? 123.799 117.775 132.572 1.00 52.61  ? 808 THR A CG2 1 
ATOM   5959 N  N   . ALA A 1 809 ? 123.270 122.159 132.791 1.00 55.34  ? 809 ALA A N   1 
ATOM   5960 C  CA  . ALA A 1 809 ? 122.588 123.443 132.914 1.00 55.34  ? 809 ALA A CA  1 
ATOM   5961 C  C   . ALA A 1 809 ? 121.128 123.255 133.307 1.00 55.34  ? 809 ALA A C   1 
ATOM   5962 O  O   . ALA A 1 809 ? 120.601 124.002 134.140 1.00 55.34  ? 809 ALA A O   1 
ATOM   5963 C  CB  . ALA A 1 809 ? 122.701 124.226 131.607 1.00 55.34  ? 809 ALA A CB  1 
ATOM   5964 N  N   . PHE A 1 810 ? 120.459 122.262 132.718 1.00 61.09  ? 810 PHE A N   1 
ATOM   5965 C  CA  . PHE A 1 810 ? 119.085 121.957 133.097 1.00 61.09  ? 810 PHE A CA  1 
ATOM   5966 C  C   . PHE A 1 810 ? 119.025 121.231 134.436 1.00 61.09  ? 810 PHE A C   1 
ATOM   5967 O  O   . PHE A 1 810 ? 118.103 121.460 135.227 1.00 61.09  ? 810 PHE A O   1 
ATOM   5968 C  CB  . PHE A 1 810 ? 118.413 121.130 131.997 1.00 61.09  ? 810 PHE A CB  1 
ATOM   5969 C  CG  . PHE A 1 810 ? 117.340 120.199 132.497 1.00 61.09  ? 810 PHE A CG  1 
ATOM   5970 C  CD1 . PHE A 1 810 ? 116.094 120.687 132.861 1.00 61.09  ? 810 PHE A CD1 1 
ATOM   5971 C  CD2 . PHE A 1 810 ? 117.574 118.835 132.587 1.00 61.09  ? 810 PHE A CD2 1 
ATOM   5972 C  CE1 . PHE A 1 810 ? 115.107 119.834 133.318 1.00 61.09  ? 810 PHE A CE1 1 
ATOM   5973 C  CE2 . PHE A 1 810 ? 116.590 117.978 133.044 1.00 61.09  ? 810 PHE A CE2 1 
ATOM   5974 C  CZ  . PHE A 1 810 ? 115.355 118.478 133.409 1.00 61.09  ? 810 PHE A CZ  1 
ATOM   5975 N  N   . GLY A 1 811 ? 119.995 120.352 134.702 1.00 58.32  ? 811 GLY A N   1 
ATOM   5976 C  CA  . GLY A 1 811 ? 119.982 119.598 135.946 1.00 58.32  ? 811 GLY A CA  1 
ATOM   5977 C  C   . GLY A 1 811 ? 120.167 120.472 137.171 1.00 58.32  ? 811 GLY A C   1 
ATOM   5978 O  O   . GLY A 1 811 ? 119.497 120.279 138.189 1.00 58.32  ? 811 GLY A O   1 
ATOM   5979 N  N   . ALA A 1 812 ? 121.076 121.443 137.094 1.00 55.08  ? 812 ALA A N   1 
ATOM   5980 C  CA  . ALA A 1 812 ? 121.276 122.381 138.190 1.00 55.08  ? 812 ALA A CA  1 
ATOM   5981 C  C   . ALA A 1 812 ? 120.252 123.507 138.197 1.00 55.08  ? 812 ALA A C   1 
ATOM   5982 O  O   . ALA A 1 812 ? 120.141 124.211 139.206 1.00 55.08  ? 812 ALA A O   1 
ATOM   5983 C  CB  . ALA A 1 812 ? 122.686 122.971 138.130 1.00 55.08  ? 812 ALA A CB  1 
ATOM   5984 N  N   . GLY A 1 813 ? 119.507 123.691 137.110 1.00 54.25  ? 813 GLY A N   1 
ATOM   5985 C  CA  . GLY A 1 813 ? 118.548 124.773 137.018 1.00 54.25  ? 813 GLY A CA  1 
ATOM   5986 C  C   . GLY A 1 813 ? 119.170 126.043 136.476 1.00 54.25  ? 813 GLY A C   1 
ATOM   5987 O  O   . GLY A 1 813 ? 120.162 126.532 137.023 1.00 54.25  ? 813 GLY A O   1 
ATOM   5988 N  N   . PHE A 1 814 ? 118.594 126.583 135.398 1.00 55.29  ? 814 PHE A N   1 
ATOM   5989 C  CA  . PHE A 1 814 ? 119.162 127.769 134.763 1.00 55.29  ? 814 PHE A CA  1 
ATOM   5990 C  C   . PHE A 1 814 ? 119.086 128.986 135.677 1.00 55.29  ? 814 PHE A C   1 
ATOM   5991 O  O   . PHE A 1 814 ? 120.048 129.757 135.772 1.00 55.29  ? 814 PHE A O   1 
ATOM   5992 C  CB  . PHE A 1 814 ? 118.450 128.050 133.440 1.00 55.29  ? 814 PHE A CB  1 
ATOM   5993 C  CG  . PHE A 1 814 ? 118.822 127.102 132.335 1.00 55.29  ? 814 PHE A CG  1 
ATOM   5994 C  CD1 . PHE A 1 814 ? 118.175 125.884 132.199 1.00 55.29  ? 814 PHE A CD1 1 
ATOM   5995 C  CD2 . PHE A 1 814 ? 119.816 127.432 131.428 1.00 55.29  ? 814 PHE A CD2 1 
ATOM   5996 C  CE1 . PHE A 1 814 ? 118.515 125.011 131.182 1.00 55.29  ? 814 PHE A CE1 1 
ATOM   5997 C  CE2 . PHE A 1 814 ? 120.160 126.564 130.408 1.00 55.29  ? 814 PHE A CE2 1 
ATOM   5998 C  CZ  . PHE A 1 814 ? 119.508 125.352 130.285 1.00 55.29  ? 814 PHE A CZ  1 
ATOM   5999 N  N   . PHE A 1 815 ? 117.956 129.178 136.356 1.00 58.04  ? 815 PHE A N   1 
ATOM   6000 C  CA  . PHE A 1 815 ? 117.796 130.325 137.239 1.00 58.04  ? 815 PHE A CA  1 
ATOM   6001 C  C   . PHE A 1 815 ? 118.449 130.129 138.601 1.00 58.04  ? 815 PHE A C   1 
ATOM   6002 O  O   . PHE A 1 815 ? 118.501 131.084 139.383 1.00 58.04  ? 815 PHE A O   1 
ATOM   6003 C  CB  . PHE A 1 815 ? 116.312 130.649 137.426 1.00 58.04  ? 815 PHE A CB  1 
ATOM   6004 C  CG  . PHE A 1 815 ? 116.016 132.122 137.467 1.00 58.04  ? 815 PHE A CG  1 
ATOM   6005 C  CD1 . PHE A 1 815 ? 115.958 132.864 136.298 1.00 58.04  ? 815 PHE A CD1 1 
ATOM   6006 C  CD2 . PHE A 1 815 ? 115.800 132.765 138.675 1.00 58.04  ? 815 PHE A CD2 1 
ATOM   6007 C  CE1 . PHE A 1 815 ? 115.688 134.219 136.333 1.00 58.04  ? 815 PHE A CE1 1 
ATOM   6008 C  CE2 . PHE A 1 815 ? 115.529 134.120 138.717 1.00 58.04  ? 815 PHE A CE2 1 
ATOM   6009 C  CZ  . PHE A 1 815 ? 115.473 134.848 137.544 1.00 58.04  ? 815 PHE A CZ  1 
ATOM   6010 N  N   . SER A 1 816 ? 118.943 128.926 138.906 1.00 60.72  ? 816 SER A N   1 
ATOM   6011 C  CA  . SER A 1 816 ? 119.627 128.703 140.174 1.00 60.72  ? 816 SER A CA  1 
ATOM   6012 C  C   . SER A 1 816 ? 120.963 129.430 140.243 1.00 60.72  ? 816 SER A C   1 
ATOM   6013 O  O   . SER A 1 816 ? 121.458 129.690 141.345 1.00 60.72  ? 816 SER A O   1 
ATOM   6014 C  CB  . SER A 1 816 ? 119.838 127.208 140.406 1.00 60.72  ? 816 SER A CB  1 
ATOM   6015 O  OG  . SER A 1 816 ? 120.627 126.641 139.375 1.00 60.72  ? 816 SER A OG  1 
ATOM   6016 N  N   . ASN A 1 817 ? 121.552 129.760 139.100 1.00 51.20  ? 817 ASN A N   1 
ATOM   6017 C  CA  . ASN A 1 817 ? 122.770 130.560 139.026 1.00 51.20  ? 817 ASN A CA  1 
ATOM   6018 C  C   . ASN A 1 817 ? 122.383 131.874 138.351 1.00 51.20  ? 817 ASN A C   1 
ATOM   6019 O  O   . ASN A 1 817 ? 122.465 132.009 137.130 1.00 51.20  ? 817 ASN A O   1 
ATOM   6020 C  CB  . ASN A 1 817 ? 123.867 129.826 138.264 1.00 51.20  ? 817 ASN A CB  1 
ATOM   6021 C  CG  . ASN A 1 817 ? 125.251 130.334 138.604 1.00 51.20  ? 817 ASN A CG  1 
ATOM   6022 O  OD1 . ASN A 1 817 ? 125.423 131.484 139.010 1.00 51.20  ? 817 ASN A OD1 1 
ATOM   6023 N  ND2 . ASN A 1 817 ? 126.250 129.476 138.445 1.00 51.20  ? 817 ASN A ND2 1 
ATOM   6024 N  N   . LYS A 1 818 ? 121.951 132.840 139.167 1.00 48.84  ? 818 LYS A N   1 
ATOM   6025 C  CA  . LYS A 1 818 ? 121.447 134.107 138.641 1.00 48.84  ? 818 LYS A CA  1 
ATOM   6026 C  C   . LYS A 1 818 ? 122.540 134.884 137.919 1.00 48.84  ? 818 LYS A C   1 
ATOM   6027 O  O   . LYS A 1 818 ? 122.283 135.525 136.890 1.00 48.84  ? 818 LYS A O   1 
ATOM   6028 C  CB  . LYS A 1 818 ? 120.860 134.940 139.780 1.00 48.84  ? 818 LYS A CB  1 
ATOM   6029 C  CG  . LYS A 1 818 ? 119.841 134.195 140.627 1.00 48.84  ? 818 LYS A CG  1 
ATOM   6030 C  CD  . LYS A 1 818 ? 120.184 134.281 142.106 1.00 48.84  ? 818 LYS A CD  1 
ATOM   6031 C  CE  . LYS A 1 818 ? 120.284 135.724 142.574 1.00 48.84  ? 818 LYS A CE  1 
ATOM   6032 N  NZ  . LYS A 1 818 ? 120.654 135.811 144.013 1.00 48.84  ? 818 LYS A NZ  1 
ATOM   6033 N  N   . TYR A 1 819 ? 123.766 134.834 138.445 1.00 47.73  ? 819 TYR A N   1 
ATOM   6034 C  CA  . TYR A 1 819 ? 124.882 135.521 137.807 1.00 47.73  ? 819 TYR A CA  1 
ATOM   6035 C  C   . TYR A 1 819 ? 125.141 134.977 136.409 1.00 47.73  ? 819 TYR A C   1 
ATOM   6036 O  O   . TYR A 1 819 ? 125.376 135.748 135.473 1.00 47.73  ? 819 TYR A O   1 
ATOM   6037 C  CB  . TYR A 1 819 ? 126.139 135.393 138.668 1.00 47.73  ? 819 TYR A CB  1 
ATOM   6038 C  CG  . TYR A 1 819 ? 126.267 136.438 139.753 1.00 47.73  ? 819 TYR A CG  1 
ATOM   6039 C  CD1 . TYR A 1 819 ? 126.720 137.718 139.459 1.00 47.73  ? 819 TYR A CD1 1 
ATOM   6040 C  CD2 . TYR A 1 819 ? 125.947 136.141 141.071 1.00 47.73  ? 819 TYR A CD2 1 
ATOM   6041 C  CE1 . TYR A 1 819 ? 126.843 138.675 140.447 1.00 47.73  ? 819 TYR A CE1 1 
ATOM   6042 C  CE2 . TYR A 1 819 ? 126.067 137.093 142.066 1.00 47.73  ? 819 TYR A CE2 1 
ATOM   6043 C  CZ  . TYR A 1 819 ? 126.516 138.357 141.748 1.00 47.73  ? 819 TYR A CZ  1 
ATOM   6044 O  OH  . TYR A 1 819 ? 126.637 139.308 142.735 1.00 47.73  ? 819 TYR A OH  1 
ATOM   6045 N  N   . VAL A 1 820 ? 125.084 133.652 136.246 1.00 44.39  ? 820 VAL A N   1 
ATOM   6046 C  CA  . VAL A 1 820 ? 125.404 133.043 134.958 1.00 44.39  ? 820 VAL A CA  1 
ATOM   6047 C  C   . VAL A 1 820 ? 124.373 133.426 133.901 1.00 44.39  ? 820 VAL A C   1 
ATOM   6048 O  O   . VAL A 1 820 ? 124.734 133.822 132.788 1.00 44.39  ? 820 VAL A O   1 
ATOM   6049 C  CB  . VAL A 1 820 ? 125.536 131.515 135.108 1.00 44.39  ? 820 VAL A CB  1 
ATOM   6050 C  CG1 . VAL A 1 820 ? 125.270 130.808 133.785 1.00 44.39  ? 820 VAL A CG1 1 
ATOM   6051 C  CG2 . VAL A 1 820 ? 126.922 131.162 135.616 1.00 44.39  ? 820 VAL A CG2 1 
ATOM   6052 N  N   . ILE A 1 821 ? 123.081 133.339 134.232 1.00 43.49  ? 821 ILE A N   1 
ATOM   6053 C  CA  . ILE A 1 821 ? 122.051 133.664 133.246 1.00 43.49  ? 821 ILE A CA  1 
ATOM   6054 C  C   . ILE A 1 821 ? 122.044 135.161 132.947 1.00 43.49  ? 821 ILE A C   1 
ATOM   6055 O  O   . ILE A 1 821 ? 121.875 135.573 131.791 1.00 43.49  ? 821 ILE A O   1 
ATOM   6056 C  CB  . ILE A 1 821 ? 120.672 133.152 133.710 1.00 43.49  ? 821 ILE A CB  1 
ATOM   6057 C  CG1 . ILE A 1 821 ? 119.562 133.639 132.773 1.00 43.49  ? 821 ILE A CG1 1 
ATOM   6058 C  CG2 . ILE A 1 821 ? 120.381 133.562 135.142 1.00 43.49  ? 821 ILE A CG2 1 
ATOM   6059 C  CD1 . ILE A 1 821 ? 118.164 133.279 133.234 1.00 43.49  ? 821 ILE A CD1 1 
ATOM   6060 N  N   . GLY A 1 822 ? 122.252 135.998 133.971 1.00 40.86  ? 822 GLY A N   1 
ATOM   6061 C  CA  . GLY A 1 822 ? 122.333 137.431 133.730 1.00 40.86  ? 822 GLY A CA  1 
ATOM   6062 C  C   . GLY A 1 822 ? 123.503 137.808 132.841 1.00 40.86  ? 822 GLY A C   1 
ATOM   6063 O  O   . GLY A 1 822 ? 123.360 138.605 131.909 1.00 40.86  ? 822 GLY A O   1 
ATOM   6064 N  N   . ALA A 1 823 ? 124.671 137.211 133.093 1.00 36.03  ? 823 ALA A N   1 
ATOM   6065 C  CA  . ALA A 1 823 ? 125.835 137.466 132.255 1.00 36.03  ? 823 ALA A CA  1 
ATOM   6066 C  C   . ALA A 1 823 ? 125.629 136.938 130.842 1.00 36.03  ? 823 ALA A C   1 
ATOM   6067 O  O   . ALA A 1 823 ? 126.058 137.571 129.875 1.00 36.03  ? 823 ALA A O   1 
ATOM   6068 C  CB  . ALA A 1 823 ? 127.079 136.845 132.886 1.00 36.03  ? 823 ALA A CB  1 
ATOM   6069 N  N   . VAL A 1 824 ? 124.982 135.778 130.703 1.00 35.69  ? 824 VAL A N   1 
ATOM   6070 C  CA  . VAL A 1 824 ? 124.729 135.215 129.381 1.00 35.69  ? 824 VAL A CA  1 
ATOM   6071 C  C   . VAL A 1 824 ? 123.817 136.133 128.580 1.00 35.69  ? 824 VAL A C   1 
ATOM   6072 O  O   . VAL A 1 824 ? 124.054 136.383 127.391 1.00 35.69  ? 824 VAL A O   1 
ATOM   6073 C  CB  . VAL A 1 824 ? 124.144 133.796 129.517 1.00 35.69  ? 824 VAL A CB  1 
ATOM   6074 C  CG1 . VAL A 1 824 ? 123.262 133.443 128.325 1.00 35.69  ? 824 VAL A CG1 1 
ATOM   6075 C  CG2 . VAL A 1 824 ? 125.260 132.785 129.676 1.00 35.69  ? 824 VAL A CG2 1 
ATOM   6076 N  N   . LEU A 1 825 ? 122.777 136.669 129.222 1.00 37.32  ? 825 LEU A N   1 
ATOM   6077 C  CA  . LEU A 1 825 ? 121.924 137.649 128.558 1.00 37.32  ? 825 LEU A CA  1 
ATOM   6078 C  C   . LEU A 1 825 ? 122.705 138.911 128.208 1.00 37.32  ? 825 LEU A C   1 
ATOM   6079 O  O   . LEU A 1 825 ? 122.475 139.517 127.153 1.00 37.32  ? 825 LEU A O   1 
ATOM   6080 C  CB  . LEU A 1 825 ? 120.723 137.981 129.443 1.00 37.32  ? 825 LEU A CB  1 
ATOM   6081 C  CG  . LEU A 1 825 ? 119.685 138.947 128.867 1.00 37.32  ? 825 LEU A CG  1 
ATOM   6082 C  CD1 . LEU A 1 825 ? 119.240 138.496 127.483 1.00 37.32  ? 825 LEU A CD1 1 
ATOM   6083 C  CD2 . LEU A 1 825 ? 118.493 139.075 129.803 1.00 37.32  ? 825 LEU A CD2 1 
ATOM   6084 N  N   . LEU A 1 826 ? 123.639 139.315 129.076 1.00 37.27  ? 826 LEU A N   1 
ATOM   6085 C  CA  . LEU A 1 826 ? 124.460 140.492 128.799 1.00 37.27  ? 826 LEU A CA  1 
ATOM   6086 C  C   . LEU A 1 826 ? 125.319 140.296 127.552 1.00 37.27  ? 826 LEU A C   1 
ATOM   6087 O  O   . LEU A 1 826 ? 125.370 141.169 126.678 1.00 37.27  ? 826 LEU A O   1 
ATOM   6088 C  CB  . LEU A 1 826 ? 125.336 140.814 130.009 1.00 37.27  ? 826 LEU A CB  1 
ATOM   6089 C  CG  . LEU A 1 826 ? 126.518 141.750 129.753 1.00 37.27  ? 826 LEU A CG  1 
ATOM   6090 C  CD1 . LEU A 1 826 ? 126.049 143.191 129.630 1.00 37.27  ? 826 LEU A CD1 1 
ATOM   6091 C  CD2 . LEU A 1 826 ? 127.560 141.610 130.850 1.00 37.27  ? 826 LEU A CD2 1 
ATOM   6092 N  N   . CYS A 1 827 ? 125.998 139.149 127.448 1.00 37.37  ? 827 CYS A N   1 
ATOM   6093 C  CA  . CYS A 1 827 ? 126.803 138.898 126.252 1.00 37.37  ? 827 CYS A CA  1 
ATOM   6094 C  C   . CYS A 1 827 ? 125.944 138.665 125.018 1.00 37.37  ? 827 CYS A C   1 
ATOM   6095 O  O   . CYS A 1 827 ? 126.379 138.983 123.909 1.00 37.37  ? 827 CYS A O   1 
ATOM   6096 C  CB  . CYS A 1 827 ? 127.764 137.721 126.435 1.00 37.37  ? 827 CYS A CB  1 
ATOM   6097 S  SG  . CYS A 1 827 ? 128.443 137.430 128.065 1.00 37.37  ? 827 CYS A SG  1 
ATOM   6098 N  N   . PHE A 1 828 ? 124.738 138.115 125.173 1.00 36.95  ? 828 PHE A N   1 
ATOM   6099 C  CA  . PHE A 1 828 ? 123.843 137.993 124.026 1.00 36.95  ? 828 PHE A CA  1 
ATOM   6100 C  C   . PHE A 1 828 ? 123.436 139.367 123.506 1.00 36.95  ? 828 PHE A C   1 
ATOM   6101 O  O   . PHE A 1 828 ? 123.441 139.610 122.293 1.00 36.95  ? 828 PHE A O   1 
ATOM   6102 C  CB  . PHE A 1 828 ? 122.613 137.170 124.405 1.00 36.95  ? 828 PHE A CB  1 
ATOM   6103 C  CG  . PHE A 1 828 ? 122.202 136.175 123.358 1.00 36.95  ? 828 PHE A CG  1 
ATOM   6104 C  CD1 . PHE A 1 828 ? 121.381 136.552 122.307 1.00 36.95  ? 828 PHE A CD1 1 
ATOM   6105 C  CD2 . PHE A 1 828 ? 122.636 134.861 123.426 1.00 36.95  ? 828 PHE A CD2 1 
ATOM   6106 C  CE1 . PHE A 1 828 ? 121.000 135.636 121.342 1.00 36.95  ? 828 PHE A CE1 1 
ATOM   6107 C  CE2 . PHE A 1 828 ? 122.258 133.941 122.465 1.00 36.95  ? 828 PHE A CE2 1 
ATOM   6108 C  CZ  . PHE A 1 828 ? 121.439 134.330 121.422 1.00 36.95  ? 828 PHE A CZ  1 
ATOM   6109 N  N   . VAL A 1 829 ? 123.119 140.290 124.417 1.00 42.34  ? 829 VAL A N   1 
ATOM   6110 C  CA  . VAL A 1 829 ? 122.797 141.660 124.023 1.00 42.34  ? 829 VAL A CA  1 
ATOM   6111 C  C   . VAL A 1 829 ? 124.004 142.329 123.373 1.00 42.34  ? 829 VAL A C   1 
ATOM   6112 O  O   . VAL A 1 829 ? 123.878 143.013 122.349 1.00 42.34  ? 829 VAL A O   1 
ATOM   6113 C  CB  . VAL A 1 829 ? 122.287 142.451 125.244 1.00 42.34  ? 829 VAL A CB  1 
ATOM   6114 C  CG1 . VAL A 1 829 ? 122.497 143.950 125.062 1.00 42.34  ? 829 VAL A CG1 1 
ATOM   6115 C  CG2 . VAL A 1 829 ? 120.819 142.141 125.499 1.00 42.34  ? 829 VAL A CG2 1 
ATOM   6116 N  N   . LEU A 1 830 ? 125.194 142.128 123.948 1.00 39.52  ? 830 LEU A N   1 
ATOM   6117 C  CA  . LEU A 1 830 ? 126.406 142.735 123.401 1.00 39.52  ? 830 LEU A CA  1 
ATOM   6118 C  C   . LEU A 1 830 ? 126.729 142.187 122.015 1.00 39.52  ? 830 LEU A C   1 
ATOM   6119 O  O   . LEU A 1 830 ? 127.156 142.937 121.130 1.00 39.52  ? 830 LEU A O   1 
ATOM   6120 C  CB  . LEU A 1 830 ? 127.575 142.510 124.358 1.00 39.52  ? 830 LEU A CB  1 
ATOM   6121 C  CG  . LEU A 1 830 ? 128.777 143.439 124.192 1.00 39.52  ? 830 LEU A CG  1 
ATOM   6122 C  CD1 . LEU A 1 830 ? 128.387 144.869 124.517 1.00 39.52  ? 830 LEU A CD1 1 
ATOM   6123 C  CD2 . LEU A 1 830 ? 129.918 142.985 125.082 1.00 39.52  ? 830 LEU A CD2 1 
ATOM   6124 N  N   . TYR A 1 831 ? 126.534 140.883 121.809 1.00 34.66  ? 831 TYR A N   1 
ATOM   6125 C  CA  . TYR A 1 831 ? 126.692 140.295 120.486 1.00 34.66  ? 831 TYR A CA  1 
ATOM   6126 C  C   . TYR A 1 831 ? 125.608 140.783 119.535 1.00 34.66  ? 831 TYR A C   1 
ATOM   6127 O  O   . TYR A 1 831 ? 125.819 140.816 118.318 1.00 34.66  ? 831 TYR A O   1 
ATOM   6128 C  CB  . TYR A 1 831 ? 126.684 138.768 120.602 1.00 34.66  ? 831 TYR A CB  1 
ATOM   6129 C  CG  . TYR A 1 831 ? 126.335 138.031 119.332 1.00 34.66  ? 831 TYR A CG  1 
ATOM   6130 C  CD1 . TYR A 1 831 ? 127.202 138.025 118.247 1.00 34.66  ? 831 TYR A CD1 1 
ATOM   6131 C  CD2 . TYR A 1 831 ? 125.140 137.339 119.219 1.00 34.66  ? 831 TYR A CD2 1 
ATOM   6132 C  CE1 . TYR A 1 831 ? 126.884 137.352 117.085 1.00 34.66  ? 831 TYR A CE1 1 
ATOM   6133 C  CE2 . TYR A 1 831 ? 124.816 136.664 118.065 1.00 34.66  ? 831 TYR A CE2 1 
ATOM   6134 C  CZ  . TYR A 1 831 ? 125.689 136.674 117.001 1.00 34.66  ? 831 TYR A CZ  1 
ATOM   6135 O  OH  . TYR A 1 831 ? 125.359 136.000 115.849 1.00 34.66  ? 831 TYR A OH  1 
ATOM   6136 N  N   . GLY A 1 832 ? 124.461 141.206 120.071 1.00 41.48  ? 832 GLY A N   1 
ATOM   6137 C  CA  . GLY A 1 832 ? 123.421 141.842 119.271 1.00 41.48  ? 832 GLY A CA  1 
ATOM   6138 C  C   . GLY A 1 832 ? 123.845 143.128 118.579 1.00 41.48  ? 832 GLY A C   1 
ATOM   6139 O  O   . GLY A 1 832 ? 123.043 143.702 117.834 1.00 41.48  ? 832 GLY A O   1 
ATOM   6140 N  N   . ILE A 1 833 ? 125.064 143.610 118.829 1.00 41.85  ? 833 ILE A N   1 
ATOM   6141 C  CA  . ILE A 1 833 ? 125.652 144.653 117.996 1.00 41.85  ? 833 ILE A CA  1 
ATOM   6142 C  C   . ILE A 1 833 ? 125.855 144.142 116.573 1.00 41.85  ? 833 ILE A C   1 
ATOM   6143 O  O   . ILE A 1 833 ? 125.699 144.896 115.603 1.00 41.85  ? 833 ILE A O   1 
ATOM   6144 C  CB  . ILE A 1 833 ? 126.967 145.143 118.646 1.00 41.85  ? 833 ILE A CB  1 
ATOM   6145 C  CG1 . ILE A 1 833 ? 126.684 146.268 119.645 1.00 41.85  ? 833 ILE A CG1 1 
ATOM   6146 C  CG2 . ILE A 1 833 ? 127.994 145.589 117.612 1.00 41.85  ? 833 ILE A CG2 1 
ATOM   6147 C  CD1 . ILE A 1 833 ? 127.915 146.761 120.375 1.00 41.85  ? 833 ILE A CD1 1 
ATOM   6148 N  N   . THR A 1 834 ? 126.158 142.847 116.427 1.00 41.75  ? 834 THR A N   1 
ATOM   6149 C  CA  . THR A 1 834 ? 126.489 142.277 115.122 1.00 41.75  ? 834 THR A CA  1 
ATOM   6150 C  C   . THR A 1 834 ? 125.313 142.345 114.152 1.00 41.75  ? 834 THR A C   1 
ATOM   6151 O  O   . THR A 1 834 ? 125.503 142.613 112.959 1.00 41.75  ? 834 THR A O   1 
ATOM   6152 C  CB  . THR A 1 834 ? 126.954 140.829 115.290 1.00 41.75  ? 834 THR A CB  1 
ATOM   6153 O  OG1 . THR A 1 834 ? 127.929 140.757 116.337 1.00 41.75  ? 834 THR A OG1 1 
ATOM   6154 C  CG2 . THR A 1 834 ? 127.565 140.303 114.004 1.00 41.75  ? 834 THR A CG2 1 
ATOM   6155 N  N   . VAL A 1 835 ? 124.091 142.103 114.637 1.00 45.12  ? 835 VAL A N   1 
ATOM   6156 C  CA  . VAL A 1 835 ? 122.935 142.105 113.746 1.00 45.12  ? 835 VAL A CA  1 
ATOM   6157 C  C   . VAL A 1 835 ? 122.620 143.513 113.249 1.00 45.12  ? 835 VAL A C   1 
ATOM   6158 O  O   . VAL A 1 835 ? 122.004 143.672 112.187 1.00 45.12  ? 835 VAL A O   1 
ATOM   6159 C  CB  . VAL A 1 835 ? 121.715 141.463 114.445 1.00 45.12  ? 835 VAL A CB  1 
ATOM   6160 C  CG1 . VAL A 1 835 ? 121.229 142.310 115.610 1.00 45.12  ? 835 VAL A CG1 1 
ATOM   6161 C  CG2 . VAL A 1 835 ? 120.587 141.164 113.456 1.00 45.12  ? 835 VAL A CG2 1 
ATOM   6162 N  N   . LEU A 1 836 ? 123.050 144.541 113.973 1.00 46.76  ? 836 LEU A N   1 
ATOM   6163 C  CA  . LEU A 1 836 ? 122.835 145.913 113.531 1.00 46.76  ? 836 LEU A CA  1 
ATOM   6164 C  C   . LEU A 1 836 ? 123.652 146.185 112.272 1.00 46.76  ? 836 LEU A C   1 
ATOM   6165 O  O   . LEU A 1 836 ? 124.856 145.903 112.250 1.00 46.76  ? 836 LEU A O   1 
ATOM   6166 C  CB  . LEU A 1 836 ? 123.217 146.895 114.634 1.00 46.76  ? 836 LEU A CB  1 
ATOM   6167 C  CG  . LEU A 1 836 ? 122.205 147.053 115.771 1.00 46.76  ? 836 LEU A CG  1 
ATOM   6168 C  CD1 . LEU A 1 836 ? 122.681 148.093 116.772 1.00 46.76  ? 836 LEU A CD1 1 
ATOM   6169 C  CD2 . LEU A 1 836 ? 120.833 147.415 115.226 1.00 46.76  ? 836 LEU A CD2 1 
ATOM   6170 N  N   . PRO A 1 837 ? 123.036 146.705 111.206 1.00 52.32  ? 837 PRO A N   1 
ATOM   6171 C  CA  . PRO A 1 837 ? 123.788 146.943 109.961 1.00 52.32  ? 837 PRO A CA  1 
ATOM   6172 C  C   . PRO A 1 837 ? 124.909 147.959 110.097 1.00 52.32  ? 837 PRO A C   1 
ATOM   6173 O  O   . PRO A 1 837 ? 125.856 147.929 109.300 1.00 52.32  ? 837 PRO A O   1 
ATOM   6174 C  CB  . PRO A 1 837 ? 122.704 147.433 108.989 1.00 52.32  ? 837 PRO A CB  1 
ATOM   6175 C  CG  . PRO A 1 837 ? 121.418 146.925 109.557 1.00 52.32  ? 837 PRO A CG  1 
ATOM   6176 C  CD  . PRO A 1 837 ? 121.596 146.960 111.043 1.00 52.32  ? 837 PRO A CD  1 
ATOM   6177 N  N   . GLY A 1 838 ? 124.836 148.858 111.080 1.00 55.97  ? 838 GLY A N   1 
ATOM   6178 C  CA  . GLY A 1 838 ? 125.862 149.875 111.233 1.00 55.97  ? 838 GLY A CA  1 
ATOM   6179 C  C   . GLY A 1 838 ? 127.185 149.352 111.752 1.00 55.97  ? 838 GLY A C   1 
ATOM   6180 O  O   . GLY A 1 838 ? 128.191 150.065 111.678 1.00 55.97  ? 838 GLY A O   1 
ATOM   6181 N  N   . ALA A 1 839 ? 127.209 148.127 112.273 1.00 53.39  ? 839 ALA A N   1 
ATOM   6182 C  CA  . ALA A 1 839 ? 128.428 147.521 112.788 1.00 53.39  ? 839 ALA A CA  1 
ATOM   6183 C  C   . ALA A 1 839 ? 128.854 146.282 112.013 1.00 53.39  ? 839 ALA A C   1 
ATOM   6184 O  O   . ALA A 1 839 ? 129.808 145.612 112.421 1.00 53.39  ? 839 ALA A O   1 
ATOM   6185 C  CB  . ALA A 1 839 ? 128.258 147.168 114.269 1.00 53.39  ? 839 ALA A CB  1 
ATOM   6186 N  N   . ARG A 1 840 ? 128.173 145.956 110.913 1.00 51.62  ? 840 ARG A N   1 
ATOM   6187 C  CA  . ARG A 1 840 ? 128.539 144.770 110.146 1.00 51.62  ? 840 ARG A CA  1 
ATOM   6188 C  C   . ARG A 1 840 ? 129.809 144.988 109.333 1.00 51.62  ? 840 ARG A C   1 
ATOM   6189 O  O   . ARG A 1 840 ? 130.523 144.024 109.037 1.00 51.62  ? 840 ARG A O   1 
ATOM   6190 C  CB  . ARG A 1 840 ? 127.388 144.359 109.230 1.00 51.62  ? 840 ARG A CB  1 
ATOM   6191 C  CG  . ARG A 1 840 ? 126.168 143.836 109.967 1.00 51.62  ? 840 ARG A CG  1 
ATOM   6192 C  CD  . ARG A 1 840 ? 125.306 142.965 109.069 1.00 51.62  ? 840 ARG A CD  1 
ATOM   6193 N  NE  . ARG A 1 840 ? 123.969 142.775 109.617 1.00 51.62  ? 840 ARG A NE  1 
ATOM   6194 C  CZ  . ARG A 1 840 ? 122.873 143.343 109.134 1.00 51.62  ? 840 ARG A CZ  1 
ATOM   6195 N  NH1 . ARG A 1 840 ? 122.916 144.142 108.080 1.00 51.62  ? 840 ARG A NH1 1 
ATOM   6196 N  NH2 . ARG A 1 840 ? 121.705 143.105 109.723 1.00 51.62  ? 840 ARG A NH2 1 
ATOM   6197 N  N   . GLU A 1 841 ? 130.102 146.236 108.959 1.00 52.90  ? 841 GLU A N   1 
ATOM   6198 C  CA  . GLU A 1 841 ? 131.292 146.505 108.156 1.00 52.90  ? 841 GLU A CA  1 
ATOM   6199 C  C   . GLU A 1 841 ? 132.568 146.302 108.963 1.00 52.90  ? 841 GLU A C   1 
ATOM   6200 O  O   . GLU A 1 841 ? 133.537 145.716 108.465 1.00 52.90  ? 841 GLU A O   1 
ATOM   6201 C  CB  . GLU A 1 841 ? 131.236 147.924 107.592 1.00 52.90  ? 841 GLU A CB  1 
ATOM   6202 C  CG  . GLU A 1 841 ? 132.051 148.116 106.323 1.00 52.90  ? 841 GLU A CG  1 
ATOM   6203 C  CD  . GLU A 1 841 ? 133.201 149.086 106.510 1.00 52.90  ? 841 GLU A CD  1 
ATOM   6204 O  OE1 . GLU A 1 841 ? 133.380 149.587 107.640 1.00 52.90  ? 841 GLU A OE1 1 
ATOM   6205 O  OE2 . GLU A 1 841 ? 133.927 149.346 105.528 1.00 52.90  ? 841 GLU A OE2 1 
ATOM   6206 N  N   . ILE A 1 842 ? 132.591 146.779 110.210 1.00 49.04  ? 842 ILE A N   1 
ATOM   6207 C  CA  . ILE A 1 842 ? 133.781 146.628 111.036 1.00 49.04  ? 842 ILE A CA  1 
ATOM   6208 C  C   . ILE A 1 842 ? 133.935 145.202 111.544 1.00 49.04  ? 842 ILE A C   1 
ATOM   6209 O  O   . ILE A 1 842 ? 135.044 144.793 111.906 1.00 49.04  ? 842 ILE A O   1 
ATOM   6210 C  CB  . ILE A 1 842 ? 133.756 147.624 112.211 1.00 49.04  ? 842 ILE A CB  1 
ATOM   6211 C  CG1 . ILE A 1 842 ? 132.541 147.373 113.107 1.00 49.04  ? 842 ILE A CG1 1 
ATOM   6212 C  CG2 . ILE A 1 842 ? 133.754 149.054 111.697 1.00 49.04  ? 842 ILE A CG2 1 
ATOM   6213 C  CD1 . ILE A 1 842 ? 132.533 148.204 114.370 1.00 49.04  ? 842 ILE A CD1 1 
ATOM   6214 N  N   . PHE A 1 843 ? 132.854 144.426 111.572 1.00 48.74  ? 843 PHE A N   1 
ATOM   6215 C  CA  . PHE A 1 843 ? 132.886 143.057 112.061 1.00 48.74  ? 843 PHE A CA  1 
ATOM   6216 C  C   . PHE A 1 843 ? 133.007 142.037 110.939 1.00 48.74  ? 843 PHE A C   1 
ATOM   6217 O  O   . PHE A 1 843 ? 132.901 140.835 111.201 1.00 48.74  ? 843 PHE A O   1 
ATOM   6218 C  CB  . PHE A 1 843 ? 131.637 142.767 112.893 1.00 48.74  ? 843 PHE A CB  1 
ATOM   6219 C  CG  . PHE A 1 843 ? 131.785 143.112 114.344 1.00 48.74  ? 843 PHE A CG  1 
ATOM   6220 C  CD1 . PHE A 1 843 ? 133.039 143.285 114.904 1.00 48.74  ? 843 PHE A CD1 1 
ATOM   6221 C  CD2 . PHE A 1 843 ? 130.669 143.268 115.148 1.00 48.74  ? 843 PHE A CD2 1 
ATOM   6222 C  CE1 . PHE A 1 843 ? 133.177 143.605 116.238 1.00 48.74  ? 843 PHE A CE1 1 
ATOM   6223 C  CE2 . PHE A 1 843 ? 130.801 143.588 116.483 1.00 48.74  ? 843 PHE A CE2 1 
ATOM   6224 C  CZ  . PHE A 1 843 ? 132.056 143.758 117.027 1.00 48.74  ? 843 PHE A CZ  1 
ATOM   6225 N  N   . SER A 1 844 ? 133.228 142.495 109.703 1.00 49.46  ? 844 SER A N   1 
ATOM   6226 C  CA  . SER A 1 844 ? 133.356 141.632 108.523 1.00 49.46  ? 844 SER A CA  1 
ATOM   6227 C  C   . SER A 1 844 ? 132.119 140.759 108.322 1.00 49.46  ? 844 SER A C   1 
ATOM   6228 O  O   . SER A 1 844 ? 132.216 139.592 107.935 1.00 49.46  ? 844 SER A O   1 
ATOM   6229 C  CB  . SER A 1 844 ? 134.624 140.775 108.591 1.00 49.46  ? 844 SER A CB  1 
ATOM   6230 O  OG  . SER A 1 844 ? 134.673 139.856 107.514 1.00 49.46  ? 844 SER A OG  1 
ATOM   6231 N  N   . ILE A 1 845 ? 130.947 141.326 108.587 1.00 44.97  ? 845 ILE A N   1 
ATOM   6232 C  CA  . ILE A 1 845 ? 129.670 140.673 108.306 1.00 44.97  ? 845 ILE A CA  1 
ATOM   6233 C  C   . ILE A 1 845 ? 129.153 141.235 106.982 1.00 44.97  ? 845 ILE A C   1 
ATOM   6234 O  O   . ILE A 1 845 ? 128.773 142.415 106.932 1.00 44.97  ? 845 ILE A O   1 
ATOM   6235 C  CB  . ILE A 1 845 ? 128.653 140.893 109.433 1.00 44.97  ? 845 ILE A CB  1 
ATOM   6236 C  CG1 . ILE A 1 845 ? 129.298 140.746 110.815 1.00 44.97  ? 845 ILE A CG1 1 
ATOM   6237 C  CG2 . ILE A 1 845 ? 127.486 139.926 109.289 1.00 44.97  ? 845 ILE A CG2 1 
ATOM   6238 C  CD1 . ILE A 1 845 ? 129.998 139.419 111.052 1.00 44.97  ? 845 ILE A CD1 1 
ATOM   6239 N  N   . PRO A 1 846 ? 129.122 140.450 105.910 1.00 45.86  ? 846 PRO A N   1 
ATOM   6240 C  CA  . PRO A 1 846 ? 128.705 140.981 104.610 1.00 45.86  ? 846 PRO A CA  1 
ATOM   6241 C  C   . PRO A 1 846 ? 127.223 140.799 104.330 1.00 45.86  ? 846 PRO A C   1 
ATOM   6242 O  O   . PRO A 1 846 ? 126.578 139.858 104.797 1.00 45.86  ? 846 PRO A O   1 
ATOM   6243 C  CB  . PRO A 1 846 ? 129.549 140.162 103.623 1.00 45.86  ? 846 PRO A CB  1 
ATOM   6244 C  CG  . PRO A 1 846 ? 129.917 138.894 104.367 1.00 45.86  ? 846 PRO A CG  1 
ATOM   6245 C  CD  . PRO A 1 846 ? 129.553 139.047 105.820 1.00 45.86  ? 846 PRO A CD  1 
ATOM   6246 N  N   . ALA A 1 847 ? 126.696 141.738 103.548 1.00 54.88  ? 847 ALA A N   1 
ATOM   6247 C  CA  . ALA A 1 847 ? 125.324 141.740 103.020 1.00 54.88  ? 847 ALA A CA  1 
ATOM   6248 C  C   . ALA A 1 847 ? 124.332 141.711 104.187 1.00 54.88  ? 847 ALA A C   1 
ATOM   6249 O  O   . ALA A 1 847 ? 124.623 142.212 105.281 1.00 54.88  ? 847 ALA A O   1 
ATOM   6250 C  CB  . ALA A 1 847 ? 125.159 140.607 102.020 1.00 54.88  ? 847 ALA A CB  1 
ATOM   6251 N  N   . SER A 1 848 ? 123.155 141.131 103.962 1.00 60.85  ? 848 SER A N   1 
ATOM   6252 C  CA  . SER A 1 848 ? 122.129 140.996 104.983 1.00 60.85  ? 848 SER A CA  1 
ATOM   6253 C  C   . SER A 1 848 ? 121.612 139.565 104.987 1.00 60.85  ? 848 SER A C   1 
ATOM   6254 O  O   . SER A 1 848 ? 121.590 138.894 103.952 1.00 60.85  ? 848 SER A O   1 
ATOM   6255 C  CB  . SER A 1 848 ? 120.970 141.975 104.752 1.00 60.85  ? 848 SER A CB  1 
ATOM   6256 O  OG  . SER A 1 848 ? 121.430 143.315 104.747 1.00 60.85  ? 848 SER A OG  1 
ATOM   6257 N  N   . PHE A 1 849 ? 121.195 139.104 106.163 1.00 63.22  ? 849 PHE A N   1 
ATOM   6258 C  CA  . PHE A 1 849 ? 120.774 137.722 106.342 1.00 63.22  ? 849 PHE A CA  1 
ATOM   6259 C  C   . PHE A 1 849 ? 119.272 137.596 106.119 1.00 63.22  ? 849 PHE A C   1 
ATOM   6260 O  O   . PHE A 1 849 ? 118.493 138.438 106.579 1.00 63.22  ? 849 PHE A O   1 
ATOM   6261 C  CB  . PHE A 1 849 ? 121.164 137.214 107.736 1.00 63.22  ? 849 PHE A CB  1 
ATOM   6262 C  CG  . PHE A 1 849 ? 120.172 137.547 108.819 1.00 63.22  ? 849 PHE A CG  1 
ATOM   6263 C  CD1 . PHE A 1 849 ? 120.114 138.821 109.358 1.00 63.22  ? 849 PHE A CD1 1 
ATOM   6264 C  CD2 . PHE A 1 849 ? 119.306 136.578 109.306 1.00 63.22  ? 849 PHE A CD2 1 
ATOM   6265 C  CE1 . PHE A 1 849 ? 119.202 139.128 110.354 1.00 63.22  ? 849 PHE A CE1 1 
ATOM   6266 C  CE2 . PHE A 1 849 ? 118.394 136.878 110.301 1.00 63.22  ? 849 PHE A CE2 1 
ATOM   6267 C  CZ  . PHE A 1 849 ? 118.343 138.154 110.826 1.00 63.22  ? 849 PHE A CZ  1 
ATOM   6268 N  N   . GLY A 1 850 ? 118.873 136.579 105.362 1.00 62.99  ? 850 GLY A N   1 
ATOM   6269 C  CA  . GLY A 1 850 ? 117.482 136.185 105.387 1.00 62.99  ? 850 GLY A CA  1 
ATOM   6270 C  C   . GLY A 1 850 ? 117.196 135.376 106.633 1.00 62.99  ? 850 GLY A C   1 
ATOM   6271 O  O   . GLY A 1 850 ? 116.531 135.855 107.556 1.00 62.99  ? 850 GLY A O   1 
ATOM   6272 N  N   . LEU A 1 851 ? 117.698 134.140 106.670 1.00 55.16  ? 851 LEU A N   1 
ATOM   6273 C  CA  . LEU A 1 851 ? 117.711 133.347 107.893 1.00 55.16  ? 851 LEU A CA  1 
ATOM   6274 C  C   . LEU A 1 851 ? 119.060 132.672 108.122 1.00 55.16  ? 851 LEU A C   1 
ATOM   6275 O  O   . LEU A 1 851 ? 119.515 132.543 109.263 1.00 55.16  ? 851 LEU A O   1 
ATOM   6276 C  CB  . LEU A 1 851 ? 116.597 132.298 107.862 1.00 55.16  ? 851 LEU A CB  1 
ATOM   6277 C  CG  . LEU A 1 851 ? 115.179 132.807 108.126 1.00 55.16  ? 851 LEU A CG  1 
ATOM   6278 C  CD1 . LEU A 1 851 ? 114.151 131.749 107.756 1.00 55.16  ? 851 LEU A CD1 1 
ATOM   6279 C  CD2 . LEU A 1 851 ? 115.020 133.230 109.579 1.00 55.16  ? 851 LEU A CD2 1 
ATOM   6280 N  N   . HIS A 1 852 ? 119.706 132.242 107.037 1.00 47.43  ? 852 HIS A N   1 
ATOM   6281 C  CA  . HIS A 1 852 ? 120.716 131.192 107.096 1.00 47.43  ? 852 HIS A CA  1 
ATOM   6282 C  C   . HIS A 1 852 ? 122.115 131.676 107.455 1.00 47.43  ? 852 HIS A C   1 
ATOM   6283 O  O   . HIS A 1 852 ? 122.979 130.841 107.741 1.00 47.43  ? 852 HIS A O   1 
ATOM   6284 C  CB  . HIS A 1 852 ? 120.763 130.444 105.761 1.00 47.43  ? 852 HIS A CB  1 
ATOM   6285 C  CG  . HIS A 1 852 ? 119.703 129.396 105.625 1.00 47.43  ? 852 HIS A CG  1 
ATOM   6286 N  ND1 . HIS A 1 852 ? 118.464 129.657 105.081 1.00 47.43  ? 852 HIS A ND1 1 
ATOM   6287 C  CD2 . HIS A 1 852 ? 119.693 128.087 105.971 1.00 47.43  ? 852 HIS A CD2 1 
ATOM   6288 C  CE1 . HIS A 1 852 ? 117.738 128.553 105.094 1.00 47.43  ? 852 HIS A CE1 1 
ATOM   6289 N  NE2 . HIS A 1 852 ? 118.461 127.586 105.629 1.00 47.43  ? 852 HIS A NE2 1 
ATOM   6290 N  N   . GLU A 1 853 ? 122.375 132.984 107.450 1.00 43.17  ? 853 GLU A N   1 
ATOM   6291 C  CA  . GLU A 1 853 ? 123.655 133.454 107.970 1.00 43.17  ? 853 GLU A CA  1 
ATOM   6292 C  C   . GLU A 1 853 ? 123.720 133.387 109.490 1.00 43.17  ? 853 GLU A C   1 
ATOM   6293 O  O   . GLU A 1 853 ? 124.801 133.571 110.059 1.00 43.17  ? 853 GLU A O   1 
ATOM   6294 C  CB  . GLU A 1 853 ? 123.932 134.884 107.504 1.00 43.17  ? 853 GLU A CB  1 
ATOM   6295 C  CG  . GLU A 1 853 ? 123.662 135.127 106.030 1.00 43.17  ? 853 GLU A CG  1 
ATOM   6296 C  CD  . GLU A 1 853 ? 123.988 136.547 105.612 1.00 43.17  ? 853 GLU A CD  1 
ATOM   6297 O  OE1 . GLU A 1 853 ? 124.523 137.306 106.447 1.00 43.17  ? 853 GLU A OE1 1 
ATOM   6298 O  OE2 . GLU A 1 853 ? 123.710 136.905 104.448 1.00 43.17  ? 853 GLU A OE2 1 
ATOM   6299 N  N   . TRP A 1 854 ? 122.595 133.129 110.147 1.00 38.40  ? 854 TRP A N   1 
ATOM   6300 C  CA  . TRP A 1 854 ? 122.476 133.008 111.592 1.00 38.40  ? 854 TRP A CA  1 
ATOM   6301 C  C   . TRP A 1 854 ? 121.991 131.635 112.026 1.00 38.40  ? 854 TRP A C   1 
ATOM   6302 O  O   . TRP A 1 854 ? 122.438 131.129 113.058 1.00 38.40  ? 854 TRP A O   1 
ATOM   6303 C  CB  . TRP A 1 854 ? 121.513 134.091 112.116 1.00 38.40  ? 854 TRP A CB  1 
ATOM   6304 C  CG  . TRP A 1 854 ? 121.537 134.354 113.603 1.00 38.40  ? 854 TRP A CG  1 
ATOM   6305 C  CD1 . TRP A 1 854 ? 121.388 133.444 114.611 1.00 38.40  ? 854 TRP A CD1 1 
ATOM   6306 C  CD2 . TRP A 1 854 ? 121.700 135.626 114.238 1.00 38.40  ? 854 TRP A CD2 1 
ATOM   6307 N  NE1 . TRP A 1 854 ? 121.457 134.068 115.830 1.00 38.40  ? 854 TRP A NE1 1 
ATOM   6308 C  CE2 . TRP A 1 854 ? 121.647 135.409 115.629 1.00 38.40  ? 854 TRP A CE2 1 
ATOM   6309 C  CE3 . TRP A 1 854 ? 121.889 136.928 113.766 1.00 38.40  ? 854 TRP A CE3 1 
ATOM   6310 C  CZ2 . TRP A 1 854 ? 121.775 136.444 116.550 1.00 38.40  ? 854 TRP A CZ2 1 
ATOM   6311 C  CZ3 . TRP A 1 854 ? 122.018 137.951 114.681 1.00 38.40  ? 854 TRP A CZ3 1 
ATOM   6312 C  CH2 . TRP A 1 854 ? 121.961 137.705 116.057 1.00 38.40  ? 854 TRP A CH2 1 
ATOM   6313 N  N   . SER A 1 855 ? 121.083 131.024 111.259 1.00 45.07  ? 855 SER A N   1 
ATOM   6314 C  CA  . SER A 1 855 ? 120.460 129.771 111.679 1.00 45.07  ? 855 SER A CA  1 
ATOM   6315 C  C   . SER A 1 855 ? 121.462 128.625 111.722 1.00 45.07  ? 855 SER A C   1 
ATOM   6316 O  O   . SER A 1 855 ? 121.411 127.791 112.631 1.00 45.07  ? 855 SER A O   1 
ATOM   6317 C  CB  . SER A 1 855 ? 119.298 129.426 110.749 1.00 45.07  ? 855 SER A CB  1 
ATOM   6318 O  OG  . SER A 1 855 ? 118.837 128.106 110.982 1.00 45.07  ? 855 SER A OG  1 
ATOM   6319 N  N   . ILE A 1 856 ? 122.373 128.561 110.747 1.00 39.49  ? 856 ILE A N   1 
ATOM   6320 C  CA  . ILE A 1 856 ? 123.383 127.504 110.741 1.00 39.49  ? 856 ILE A CA  1 
ATOM   6321 C  C   . ILE A 1 856 ? 124.304 127.641 111.945 1.00 39.49  ? 856 ILE A C   1 
ATOM   6322 O  O   . ILE A 1 856 ? 124.628 126.652 112.615 1.00 39.49  ? 856 ILE A O   1 
ATOM   6323 C  CB  . ILE A 1 856 ? 124.171 127.523 109.418 1.00 39.49  ? 856 ILE A CB  1 
ATOM   6324 C  CG1 . ILE A 1 856 ? 123.221 127.373 108.227 1.00 39.49  ? 856 ILE A CG1 1 
ATOM   6325 C  CG2 . ILE A 1 856 ? 125.235 126.432 109.409 1.00 39.49  ? 856 ILE A CG2 1 
ATOM   6326 C  CD1 . ILE A 1 856 ? 122.708 125.962 108.021 1.00 39.49  ? 856 ILE A CD1 1 
ATOM   6327 N  N   . ALA A 1 857 ? 124.729 128.871 112.244 1.00 37.79  ? 857 ALA A N   1 
ATOM   6328 C  CA  . ALA A 1 857 ? 125.585 129.109 113.402 1.00 37.79  ? 857 ALA A CA  1 
ATOM   6329 C  C   . ALA A 1 857 ? 124.871 128.769 114.703 1.00 37.79  ? 857 ALA A C   1 
ATOM   6330 O  O   . ALA A 1 857 ? 125.463 128.161 115.603 1.00 37.79  ? 857 ALA A O   1 
ATOM   6331 C  CB  . ALA A 1 857 ? 126.047 130.564 113.414 1.00 37.79  ? 857 ALA A CB  1 
ATOM   6332 N  N   . ALA A 1 858 ? 123.598 129.155 114.819 1.00 47.23  ? 858 ALA A N   1 
ATOM   6333 C  CA  . ALA A 1 858 ? 122.838 128.863 116.030 1.00 47.23  ? 858 ALA A CA  1 
ATOM   6334 C  C   . ALA A 1 858 ? 122.624 127.366 116.203 1.00 47.23  ? 858 ALA A C   1 
ATOM   6335 O  O   . ALA A 1 858 ? 122.734 126.844 117.317 1.00 47.23  ? 858 ALA A O   1 
ATOM   6336 C  CB  . ALA A 1 858 ? 121.499 129.599 116.000 1.00 47.23  ? 858 ALA A CB  1 
ATOM   6337 N  N   . GLY A 1 859 ? 122.323 126.659 115.110 1.00 48.50  ? 859 GLY A N   1 
ATOM   6338 C  CA  . GLY A 1 859 ? 122.162 125.218 115.191 1.00 48.50  ? 859 GLY A CA  1 
ATOM   6339 C  C   . GLY A 1 859 ? 123.450 124.507 115.551 1.00 48.50  ? 859 GLY A C   1 
ATOM   6340 O  O   . GLY A 1 859 ? 123.446 123.560 116.339 1.00 48.50  ? 859 GLY A O   1 
ATOM   6341 N  N   . LEU A 1 860 ? 124.574 124.959 114.984 1.00 41.92  ? 860 LEU A N   1 
ATOM   6342 C  CA  . LEU A 1 860 ? 125.863 124.372 115.333 1.00 41.92  ? 860 LEU A CA  1 
ATOM   6343 C  C   . LEU A 1 860 ? 126.222 124.636 116.790 1.00 41.92  ? 860 LEU A C   1 
ATOM   6344 O  O   . LEU A 1 860 ? 126.724 123.742 117.477 1.00 41.92  ? 860 LEU A O   1 
ATOM   6345 C  CB  . LEU A 1 860 ? 126.953 124.903 114.404 1.00 41.92  ? 860 LEU A CB  1 
ATOM   6346 C  CG  . LEU A 1 860 ? 127.135 124.097 113.119 1.00 41.92  ? 860 LEU A CG  1 
ATOM   6347 C  CD1 . LEU A 1 860 ? 128.070 124.808 112.159 1.00 41.92  ? 860 LEU A CD1 1 
ATOM   6348 C  CD2 . LEU A 1 860 ? 127.653 122.706 113.446 1.00 41.92  ? 860 LEU A CD2 1 
ATOM   6349 N  N   . ALA A 1 861 ? 125.965 125.852 117.283 1.00 46.19  ? 861 ALA A N   1 
ATOM   6350 C  CA  . ALA A 1 861 ? 126.245 126.158 118.683 1.00 46.19  ? 861 ALA A CA  1 
ATOM   6351 C  C   . ALA A 1 861 ? 125.362 125.341 119.621 1.00 46.19  ? 861 ALA A C   1 
ATOM   6352 O  O   . ALA A 1 861 ? 125.842 124.823 120.638 1.00 46.19  ? 861 ALA A O   1 
ATOM   6353 C  CB  . ALA A 1 861 ? 126.064 127.653 118.941 1.00 46.19  ? 861 ALA A CB  1 
ATOM   6354 N  N   . LEU A 1 862 ? 124.072 125.215 119.293 1.00 51.80  ? 862 LEU A N   1 
ATOM   6355 C  CA  . LEU A 1 862 ? 123.159 124.427 120.115 1.00 51.80  ? 862 LEU A CA  1 
ATOM   6356 C  C   . LEU A 1 862 ? 123.538 122.952 120.107 1.00 51.80  ? 862 LEU A C   1 
ATOM   6357 O  O   . LEU A 1 862 ? 123.501 122.291 121.152 1.00 51.80  ? 862 LEU A O   1 
ATOM   6358 C  CB  . LEU A 1 862 ? 121.721 124.618 119.633 1.00 51.80  ? 862 LEU A CB  1 
ATOM   6359 C  CG  . LEU A 1 862 ? 120.832 125.538 120.474 1.00 51.80  ? 862 LEU A CG  1 
ATOM   6360 C  CD1 . LEU A 1 862 ? 121.298 126.979 120.370 1.00 51.80  ? 862 LEU A CD1 1 
ATOM   6361 C  CD2 . LEU A 1 862 ? 119.374 125.418 120.054 1.00 51.80  ? 862 LEU A CD2 1 
ATOM   6362 N  N   . ALA A 1 863 ? 123.908 122.418 118.939 1.00 53.48  ? 863 ALA A N   1 
ATOM   6363 C  CA  . ALA A 1 863 ? 124.385 121.043 118.871 1.00 53.48  ? 863 ALA A CA  1 
ATOM   6364 C  C   . ALA A 1 863 ? 125.671 120.869 119.661 1.00 53.48  ? 863 ALA A C   1 
ATOM   6365 O  O   . ALA A 1 863 ? 125.862 119.836 120.311 1.00 53.48  ? 863 ALA A O   1 
ATOM   6366 C  CB  . ALA A 1 863 ? 124.593 120.625 117.416 1.00 53.48  ? 863 ALA A CB  1 
ATOM   6367 N  N   . ALA A 1 864 ? 126.550 121.874 119.636 1.00 51.42  ? 864 ALA A N   1 
ATOM   6368 C  CA  . ALA A 1 864 ? 127.785 121.811 120.408 1.00 51.42  ? 864 ALA A CA  1 
ATOM   6369 C  C   . ALA A 1 864 ? 127.498 121.725 121.900 1.00 51.42  ? 864 ALA A C   1 
ATOM   6370 O  O   . ALA A 1 864 ? 128.047 120.866 122.598 1.00 51.42  ? 864 ALA A O   1 
ATOM   6371 C  CB  . ALA A 1 864 ? 128.659 123.027 120.098 1.00 51.42  ? 864 ALA A CB  1 
ATOM   6372 N  N   . VAL A 1 865 ? 126.619 122.596 122.407 1.00 49.76  ? 865 VAL A N   1 
ATOM   6373 C  CA  . VAL A 1 865 ? 126.387 122.583 123.849 1.00 49.76  ? 865 VAL A CA  1 
ATOM   6374 C  C   . VAL A 1 865 ? 125.591 121.350 124.254 1.00 49.76  ? 865 VAL A C   1 
ATOM   6375 O  O   . VAL A 1 865 ? 125.781 120.824 125.356 1.00 49.76  ? 865 VAL A O   1 
ATOM   6376 C  CB  . VAL A 1 865 ? 125.700 123.869 124.349 1.00 49.76  ? 865 VAL A CB  1 
ATOM   6377 C  CG1 . VAL A 1 865 ? 126.727 124.977 124.535 1.00 49.76  ? 865 VAL A CG1 1 
ATOM   6378 C  CG2 . VAL A 1 865 ? 124.548 124.285 123.466 1.00 49.76  ? 865 VAL A CG2 1 
ATOM   6379 N  N   . VAL A 1 866 ? 124.698 120.855 123.390 1.00 57.61  ? 866 VAL A N   1 
ATOM   6380 C  CA  . VAL A 1 866 ? 123.963 119.650 123.762 1.00 57.61  ? 866 VAL A CA  1 
ATOM   6381 C  C   . VAL A 1 866 ? 124.878 118.426 123.731 1.00 57.61  ? 866 VAL A C   1 
ATOM   6382 O  O   . VAL A 1 866 ? 124.759 117.545 124.591 1.00 57.61  ? 866 VAL A O   1 
ATOM   6383 C  CB  . VAL A 1 866 ? 122.694 119.480 122.894 1.00 57.61  ? 866 VAL A CB  1 
ATOM   6384 C  CG1 . VAL A 1 866 ? 122.978 118.839 121.539 1.00 57.61  ? 866 VAL A CG1 1 
ATOM   6385 C  CG2 . VAL A 1 866 ? 121.648 118.675 123.651 1.00 57.61  ? 866 VAL A CG2 1 
ATOM   6386 N  N   . MET A 1 867 ? 125.832 118.374 122.789 1.00 61.20  ? 867 MET A N   1 
ATOM   6387 C  CA  . MET A 1 867 ? 126.854 117.329 122.790 1.00 61.20  ? 867 MET A CA  1 
ATOM   6388 C  C   . MET A 1 867 ? 127.697 117.412 124.051 1.00 61.20  ? 867 MET A C   1 
ATOM   6389 O  O   . MET A 1 867 ? 128.027 116.392 124.669 1.00 61.20  ? 867 MET A O   1 
ATOM   6390 C  CB  . MET A 1 867 ? 127.748 117.483 121.558 1.00 61.20  ? 867 MET A CB  1 
ATOM   6391 C  CG  . MET A 1 867 ? 127.298 116.761 120.298 1.00 61.20  ? 867 MET A CG  1 
ATOM   6392 S  SD  . MET A 1 867 ? 126.746 115.066 120.536 1.00 61.20  ? 867 MET A SD  1 
ATOM   6393 C  CE  . MET A 1 867 ? 125.984 114.744 118.949 1.00 61.20  ? 867 MET A CE  1 
ATOM   6394 N  N   . MET A 1 868 ? 128.038 118.636 124.442 1.00 58.33  ? 868 MET A N   1 
ATOM   6395 C  CA  . MET A 1 868 ? 128.845 118.893 125.623 1.00 58.33  ? 868 MET A CA  1 
ATOM   6396 C  C   . MET A 1 868 ? 128.121 118.389 126.866 1.00 58.33  ? 868 MET A C   1 
ATOM   6397 O  O   . MET A 1 868 ? 128.710 117.725 127.732 1.00 58.33  ? 868 MET A O   1 
ATOM   6398 C  CB  . MET A 1 868 ? 129.060 120.403 125.675 1.00 58.33  ? 868 MET A CB  1 
ATOM   6399 C  CG  . MET A 1 868 ? 130.449 120.891 125.372 1.00 58.33  ? 868 MET A CG  1 
ATOM   6400 S  SD  . MET A 1 868 ? 130.369 122.687 125.218 1.00 58.33  ? 868 MET A SD  1 
ATOM   6401 C  CE  . MET A 1 868 ? 132.057 123.076 124.814 1.00 58.33  ? 868 MET A CE  1 
ATOM   6402 N  N   . GLU A 1 869 ? 126.814 118.650 126.928 1.00 66.17  ? 869 GLU A N   1 
ATOM   6403 C  CA  . GLU A 1 869 ? 126.004 118.225 128.060 1.00 66.17  ? 869 GLU A CA  1 
ATOM   6404 C  C   . GLU A 1 869 ? 125.849 116.709 128.109 1.00 66.17  ? 869 GLU A C   1 
ATOM   6405 O  O   . GLU A 1 869 ? 125.894 116.126 129.196 1.00 66.17  ? 869 GLU A O   1 
ATOM   6406 C  CB  . GLU A 1 869 ? 124.638 118.909 128.014 1.00 66.17  ? 869 GLU A CB  1 
ATOM   6407 C  CG  . GLU A 1 869 ? 124.634 120.313 128.605 1.00 66.17  ? 869 GLU A CG  1 
ATOM   6408 C  CD  . GLU A 1 869 ? 123.263 120.958 128.579 1.00 66.17  ? 869 GLU A CD  1 
ATOM   6409 O  OE1 . GLU A 1 869 ? 122.312 120.321 128.078 1.00 66.17  ? 869 GLU A OE1 1 
ATOM   6410 O  OE2 . GLU A 1 869 ? 123.135 122.106 129.053 1.00 66.17  ? 869 GLU A OE2 1 
ATOM   6411 N  N   . ILE A 1 870 ? 125.660 116.041 126.962 1.00 70.93  ? 870 ILE A N   1 
ATOM   6412 C  CA  . ILE A 1 870 ? 125.521 114.587 127.071 1.00 70.93  ? 870 ILE A CA  1 
ATOM   6413 C  C   . ILE A 1 870 ? 126.875 113.955 127.362 1.00 70.93  ? 870 ILE A C   1 
ATOM   6414 O  O   . ILE A 1 870 ? 126.941 112.866 127.937 1.00 70.93  ? 870 ILE A O   1 
ATOM   6415 C  CB  . ILE A 1 870 ? 124.880 113.916 125.839 1.00 70.93  ? 870 ILE A CB  1 
ATOM   6416 C  CG1 . ILE A 1 870 ? 125.331 114.543 124.533 1.00 70.93  ? 870 ILE A CG1 1 
ATOM   6417 C  CG2 . ILE A 1 870 ? 123.361 113.978 125.935 1.00 70.93  ? 870 ILE A CG2 1 
ATOM   6418 C  CD1 . ILE A 1 870 ? 125.144 113.623 123.358 1.00 70.93  ? 870 ILE A CD1 1 
ATOM   6419 N  N   . ILE A 1 871 ? 127.971 114.617 126.980 1.00 68.51  ? 871 ILE A N   1 
ATOM   6420 C  CA  . ILE A 1 871 ? 129.292 114.178 127.424 1.00 68.51  ? 871 ILE A CA  1 
ATOM   6421 C  C   . ILE A 1 871 ? 129.386 114.262 128.943 1.00 68.51  ? 871 ILE A C   1 
ATOM   6422 O  O   . ILE A 1 871 ? 129.903 113.350 129.604 1.00 68.51  ? 871 ILE A O   1 
ATOM   6423 C  CB  . ILE A 1 871 ? 130.390 115.007 126.727 1.00 68.51  ? 871 ILE A CB  1 
ATOM   6424 C  CG1 . ILE A 1 871 ? 130.810 114.341 125.416 1.00 68.51  ? 871 ILE A CG1 1 
ATOM   6425 C  CG2 . ILE A 1 871 ? 131.609 115.205 127.627 1.00 68.51  ? 871 ILE A CG2 1 
ATOM   6426 C  CD1 . ILE A 1 871 ? 131.822 115.141 124.623 1.00 68.51  ? 871 ILE A CD1 1 
ATOM   6427 N  N   . LYS A 1 872 ? 128.857 115.346 129.521 1.00 64.34  ? 872 LYS A N   1 
ATOM   6428 C  CA  . LYS A 1 872 ? 128.831 115.471 130.977 1.00 64.34  ? 872 LYS A CA  1 
ATOM   6429 C  C   . LYS A 1 872 ? 127.970 114.385 131.623 1.00 64.34  ? 872 LYS A C   1 
ATOM   6430 O  O   . LYS A 1 872 ? 128.347 113.818 132.656 1.00 64.34  ? 872 LYS A O   1 
ATOM   6431 C  CB  . LYS A 1 872 ? 128.336 116.861 131.376 1.00 64.34  ? 872 LYS A CB  1 
ATOM   6432 C  CG  . LYS A 1 872 ? 129.429 117.919 131.397 1.00 64.34  ? 872 LYS A CG  1 
ATOM   6433 C  CD  . LYS A 1 872 ? 128.865 119.316 131.615 1.00 64.34  ? 872 LYS A CD  1 
ATOM   6434 C  CE  . LYS A 1 872 ? 127.856 119.346 132.751 1.00 64.34  ? 872 LYS A CE  1 
ATOM   6435 N  NZ  . LYS A 1 872 ? 127.389 120.730 133.034 1.00 64.34  ? 872 LYS A NZ  1 
ATOM   6436 N  N   . VAL A 1 873 ? 126.811 114.080 131.031 1.00 74.45  ? 873 VAL A N   1 
ATOM   6437 C  CA  . VAL A 1 873 ? 125.942 113.036 131.583 1.00 74.45  ? 873 VAL A CA  1 
ATOM   6438 C  C   . VAL A 1 873 ? 126.595 111.662 131.460 1.00 74.45  ? 873 VAL A C   1 
ATOM   6439 O  O   . VAL A 1 873 ? 126.469 110.819 132.357 1.00 74.45  ? 873 VAL A O   1 
ATOM   6440 C  CB  . VAL A 1 873 ? 124.551 113.059 130.918 1.00 74.45  ? 873 VAL A CB  1 
ATOM   6441 C  CG1 . VAL A 1 873 ? 123.609 112.116 131.643 1.00 74.45  ? 873 VAL A CG1 1 
ATOM   6442 C  CG2 . VAL A 1 873 ? 123.963 114.446 130.973 1.00 74.45  ? 873 VAL A CG2 1 
ATOM   6443 N  N   . VAL A 1 874 ? 127.285 111.408 130.345 1.00 79.53  ? 874 VAL A N   1 
ATOM   6444 C  CA  . VAL A 1 874 ? 127.999 110.146 130.167 1.00 79.53  ? 874 VAL A CA  1 
ATOM   6445 C  C   . VAL A 1 874 ? 129.097 110.011 131.214 1.00 79.53  ? 874 VAL A C   1 
ATOM   6446 O  O   . VAL A 1 874 ? 129.290 108.938 131.800 1.00 79.53  ? 874 VAL A O   1 
ATOM   6447 C  CB  . VAL A 1 874 ? 128.550 110.048 128.730 1.00 79.53  ? 874 VAL A CB  1 
ATOM   6448 C  CG1 . VAL A 1 874 ? 129.728 109.084 128.651 1.00 79.53  ? 874 VAL A CG1 1 
ATOM   6449 C  CG2 . VAL A 1 874 ? 127.448 109.620 127.771 1.00 79.53  ? 874 VAL A CG2 1 
ATOM   6450 N  N   . GLN A 1 875 ? 129.818 111.104 131.482 1.00 77.30  ? 875 GLN A N   1 
ATOM   6451 C  CA  . GLN A 1 875 ? 130.779 111.101 132.580 1.00 77.30  ? 875 GLN A CA  1 
ATOM   6452 C  C   . GLN A 1 875 ? 130.092 110.890 133.925 1.00 77.30  ? 875 GLN A C   1 
ATOM   6453 O  O   . GLN A 1 875 ? 130.699 110.344 134.852 1.00 77.30  ? 875 GLN A O   1 
ATOM   6454 C  CB  . GLN A 1 875 ? 131.574 112.406 132.586 1.00 77.30  ? 875 GLN A CB  1 
ATOM   6455 C  CG  . GLN A 1 875 ? 132.591 112.512 131.463 1.00 77.30  ? 875 GLN A CG  1 
ATOM   6456 C  CD  . GLN A 1 875 ? 133.717 111.507 131.601 1.00 77.30  ? 875 GLN A CD  1 
ATOM   6457 O  OE1 . GLN A 1 875 ? 134.282 111.334 132.682 1.00 77.30  ? 875 GLN A OE1 1 
ATOM   6458 N  NE2 . GLN A 1 875 ? 134.050 110.836 130.505 1.00 77.30  ? 875 GLN A NE2 1 
ATOM   6459 N  N   . ASN A 1 876 ? 128.835 111.322 134.055 1.00 73.34  ? 876 ASN A N   1 
ATOM   6460 C  CA  . ASN A 1 876 ? 128.065 111.026 135.258 1.00 73.34  ? 876 ASN A CA  1 
ATOM   6461 C  C   . ASN A 1 876 ? 127.547 109.592 135.274 1.00 73.34  ? 876 ASN A C   1 
ATOM   6462 O  O   . ASN A 1 876 ? 127.471 108.978 136.344 1.00 73.34  ? 876 ASN A O   1 
ATOM   6463 C  CB  . ASN A 1 876 ? 126.890 111.995 135.389 1.00 73.34  ? 876 ASN A CB  1 
ATOM   6464 C  CG  . ASN A 1 876 ? 127.331 113.420 135.643 1.00 73.34  ? 876 ASN A CG  1 
ATOM   6465 O  OD1 . ASN A 1 876 ? 128.514 113.690 135.851 1.00 73.34  ? 876 ASN A OD1 1 
ATOM   6466 N  ND2 . ASN A 1 876 ? 126.379 114.343 135.624 1.00 73.34  ? 876 ASN A ND2 1 
ATOM   6467 N  N   . LYS A 1 877 ? 127.187 109.047 134.111 1.00 84.28  ? 877 LYS A N   1 
ATOM   6468 C  CA  . LYS A 1 877 ? 126.567 107.726 134.033 1.00 84.28  ? 877 LYS A CA  1 
ATOM   6469 C  C   . LYS A 1 877 ? 127.598 106.625 133.799 1.00 84.28  ? 877 LYS A C   1 
ATOM   6470 O  O   . LYS A 1 877 ? 127.714 105.693 134.602 1.00 84.28  ? 877 LYS A O   1 
ATOM   6471 C  CB  . LYS A 1 877 ? 125.506 107.715 132.926 1.00 84.28  ? 877 LYS A CB  1 
ATOM   6472 C  CG  . LYS A 1 877 ? 124.476 106.601 133.046 1.00 84.28  ? 877 LYS A CG  1 
ATOM   6473 C  CD  . LYS A 1 877 ? 124.734 105.499 132.029 1.00 84.28  ? 877 LYS A CD  1 
ATOM   6474 C  CE  . LYS A 1 877 ? 123.723 104.372 132.163 1.00 84.28  ? 877 LYS A CE  1 
ATOM   6475 N  NZ  . LYS A 1 877 ? 123.924 103.319 131.131 1.00 84.28  ? 877 LYS A NZ  1 
ATOM   6476 N  N   . PHE A 1 878 ? 128.350 106.718 132.702 1.00 90.44  ? 878 PHE A N   1 
ATOM   6477 C  CA  . PHE A 1 878 ? 129.333 105.686 132.385 1.00 90.44  ? 878 PHE A CA  1 
ATOM   6478 C  C   . PHE A 1 878 ? 130.563 105.811 133.276 1.00 90.44  ? 878 PHE A C   1 
ATOM   6479 O  O   . PHE A 1 878 ? 130.914 104.877 134.007 1.00 90.44  ? 878 PHE A O   1 
ATOM   6480 C  CB  . PHE A 1 878 ? 129.719 105.772 130.905 1.00 90.44  ? 878 PHE A CB  1 
ATOM   6481 C  CG  . PHE A 1 878 ? 131.041 105.134 130.582 1.00 90.44  ? 878 PHE A CG  1 
ATOM   6482 C  CD1 . PHE A 1 878 ? 131.199 103.758 130.646 1.00 90.44  ? 878 PHE A CD1 1 
ATOM   6483 C  CD2 . PHE A 1 878 ? 132.126 105.911 130.210 1.00 90.44  ? 878 PHE A CD2 1 
ATOM   6484 C  CE1 . PHE A 1 878 ? 132.415 103.171 130.348 1.00 90.44  ? 878 PHE A CE1 1 
ATOM   6485 C  CE2 . PHE A 1 878 ? 133.345 105.330 129.911 1.00 90.44  ? 878 PHE A CE2 1 
ATOM   6486 C  CZ  . PHE A 1 878 ? 133.489 103.958 129.980 1.00 90.44  ? 878 PHE A CZ  1 
ATOM   6487 N  N   . PHE A 1 879 ? 131.187 106.985 133.228 1.00 90.10  ? 879 PHE A N   1 
ATOM   6488 C  CA  . PHE A 1 879 ? 132.430 107.167 134.011 1.00 90.10  ? 879 PHE A CA  1 
ATOM   6489 C  C   . PHE A 1 879 ? 132.082 107.650 135.416 1.00 90.10  ? 879 PHE A C   1 
ATOM   6490 O  O   . PHE A 1 879 ? 130.898 107.610 135.805 1.00 90.10  ? 879 PHE A O   1 
ATOM   6491 C  CB  . PHE A 1 879 ? 133.374 108.143 133.309 1.00 90.10  ? 879 PHE A CB  1 
ATOM   6492 C  CG  . PHE A 1 879 ? 134.618 107.494 132.762 1.00 90.10  ? 879 PHE A CG  1 
ATOM   6493 C  CD1 . PHE A 1 879 ? 134.925 106.182 133.080 1.00 90.10  ? 879 PHE A CD1 1 
ATOM   6494 C  CD2 . PHE A 1 879 ? 135.479 108.190 131.930 1.00 90.10  ? 879 PHE A CD2 1 
ATOM   6495 C  CE1 . PHE A 1 879 ? 136.068 105.579 132.577 1.00 90.10  ? 879 PHE A CE1 1 
ATOM   6496 C  CE2 . PHE A 1 879 ? 136.621 107.587 131.428 1.00 90.10  ? 879 PHE A CE2 1 
ATOM   6497 C  CZ  . PHE A 1 879 ? 136.913 106.283 131.753 1.00 90.10  ? 879 PHE A CZ  1 
ATOM   6498 N  N   . LYS A 1 880 ? 133.100 108.085 136.153 1.00 93.41  ? 880 LYS A N   1 
ATOM   6499 C  CA  . LYS A 1 880 ? 132.889 108.568 137.512 1.00 93.41  ? 880 LYS A CA  1 
ATOM   6500 C  C   . LYS A 1 880 ? 133.138 110.070 137.603 1.00 93.41  ? 880 LYS A C   1 
ATOM   6501 O  O   . LYS A 1 880 ? 133.939 110.623 136.850 1.00 93.41  ? 880 LYS A O   1 
ATOM   6502 C  CB  . LYS A 1 880 ? 133.795 107.822 138.493 1.00 93.41  ? 880 LYS A CB  1 
ATOM   6503 C  CG  . LYS A 1 880 ? 133.687 106.308 138.408 1.00 93.41  ? 880 LYS A CG  1 
ATOM   6504 C  CD  . LYS A 1 880 ? 132.270 105.837 138.692 1.00 93.41  ? 880 LYS A CD  1 
ATOM   6505 C  CE  . LYS A 1 880 ? 131.888 106.077 140.144 1.00 93.41  ? 880 LYS A CE  1 
ATOM   6506 N  NZ  . LYS A 1 880 ? 130.498 105.630 140.435 1.00 93.41  ? 880 LYS A NZ  1 
HETATM 6507 CA CA  . CA  B 2 .   ? 141.882 136.717 126.868 1.00 41.10  ? 901 CA  A CA  1 
# 
