data_9EUL
# 
_entry.id   9EUL 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EUL         pdb_00009eul 10.2210/pdb9eul/pdb 
WWPDB D_1292136747 ?            ?                   
EMDB  EMD-19974    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-09 ? 
2 'EM metadata'     1 0 2025-04-09 ? 
3 FSC               1 0 2025-04-09 ? 
4 'Half map'        1 0 2025-04-09 1 
5 'Half map'        1 0 2025-04-09 2 
6 Image             1 0 2025-04-09 ? 
7 Mask              1 0 2025-04-09 1 
8 'Primary map'     1 0 2025-04-09 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EUL 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of Staphylococcus aureus bacteriophage phi812 central spike protein - knob and petal domains' 
_pdbx_database_related.db_id          EMD-19974 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              pavel.plevka@ceitec.muni.cz 
_pdbx_contact_author.name_first         Pavel 
_pdbx_contact_author.name_last          Plevka 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4215-3315 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Binovsky, J.'       1 0000-0001-7647-5211 
'Pichel-Beleiro, A.' 2 ?                   
'van Raaij, M.J.'    3 0000-0002-4781-1375 
'Plevka, P.'         4 0000-0003-4215-3315 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cell attachment and tail contraction of S. aureus phage phi812' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Binovsky, J.'       1 0000-0001-7647-5211 
primary 'Pichel-Beleiro, A.' 2 ?                   
primary 'van Raaij, M.J.'    3 0000-0002-4781-1375 
primary 'Plevka, P.'         4 0000-0003-4215-3315 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'GP-PDE domain-containing protein' 
_entity.formula_weight             94274.195 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'central spike protein - knob and petal domains' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GSDDLNVKGLVLATVSKINYKYQSVEVKVNNLTLGSRIGDDGSLAVPYPKSFIGRTPEGSVFGTKPLITEGSVVLIGFLN
DDINSPIILSVYGDNEQNKMINTNPLDGGKFDTESVYKYSSSLYEILPSLNYKYDDGEGTSIRTYNGKSFFSMTSGEEEK
PQATDFYTGTEYQDLFTSYYGNKTLIEPRIQKAPNMLFKHQGVFYDDGTPDNHITTLFISERGDIRASVLNTETQKRTTQ
EMSSDGSYRVIKQDDDLMLDEAQVWIEYGISEDNKFYIKNDKHKFEFTDEGIYIDDKPMLENLDESIAEAMKNLNEIQKE
LDDINYLLKGVGKDNLEELIESTKESIEASKKATSDVNRLTTQIAEVSGRTEGIITQFQKFRDETFKDFYEDASTVINEV
NQNFPTMKTDVKTLKTKVDNLEKTEIPNIKTRLTELENNNNNADKIISDRGEHIGAMIQLEENVTVPMRKYMPIPWSKVT
YNNAEFWDSNNPTRLVVPKGITKVRVAGNVLWDSNATGQRMLRILKNGTYSIGLPYTRDVAISTAPQNGTSGVIPVKEGD
YFEFEAFQDSEGDRQFRADPYTWFSIEAIELETETMEKDFMLIGHRGATGYTDEHTIKGYQMALDKGADYIELDLQLTKD
NKLLCMHDSTIDRTTTGTGKVGDMTLSYIQTNFTSLNGEPIPSLDDVLNHFGTKVKYYIETKRPFDANMDRELLTQLKAK
GLIGIGSERFQVIIQSFARESLINIHNQFSNIPLAYLTSTFSESEMDDCLSYGFYAIAPKYTTITKELVDLAHSKGLKVH
AWTVNTKEEMQSLIQMGVDGFFTNYLDEYKKI
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSDDLNVKGLVLATVSKINYKYQSVEVKVNNLTLGSRIGDDGSLAVPYPKSFIGRTPEGSVFGTKPLITEGSVVLIGFLN
DDINSPIILSVYGDNEQNKMINTNPLDGGKFDTESVYKYSSSLYEILPSLNYKYDDGEGTSIRTYNGKSFFSMTSGEEEK
PQATDFYTGTEYQDLFTSYYGNKTLIEPRIQKAPNMLFKHQGVFYDDGTPDNHITTLFISERGDIRASVLNTETQKRTTQ
EMSSDGSYRVIKQDDDLMLDEAQVWIEYGISEDNKFYIKNDKHKFEFTDEGIYIDDKPMLENLDESIAEAMKNLNEIQKE
LDDINYLLKGVGKDNLEELIESTKESIEASKKATSDVNRLTTQIAEVSGRTEGIITQFQKFRDETFKDFYEDASTVINEV
NQNFPTMKTDVKTLKTKVDNLEKTEIPNIKTRLTELENNNNNADKIISDRGEHIGAMIQLEENVTVPMRKYMPIPWSKVT
YNNAEFWDSNNPTRLVVPKGITKVRVAGNVLWDSNATGQRMLRILKNGTYSIGLPYTRDVAISTAPQNGTSGVIPVKEGD
YFEFEAFQDSEGDRQFRADPYTWFSIEAIELETETMEKDFMLIGHRGATGYTDEHTIKGYQMALDKGADYIELDLQLTKD
NKLLCMHDSTIDRTTTGTGKVGDMTLSYIQTNFTSLNGEPIPSLDDVLNHFGTKVKYYIETKRPFDANMDRELLTQLKAK
GLIGIGSERFQVIIQSFARESLINIHNQFSNIPLAYLTSTFSESEMDDCLSYGFYAIAPKYTTITKELVDLAHSKGLKVH
AWTVNTKEEMQSLIQMGVDGFFTNYLDEYKKI
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   ASP n 
1 4   ASP n 
1 5   LEU n 
1 6   ASN n 
1 7   VAL n 
1 8   LYS n 
1 9   GLY n 
1 10  LEU n 
1 11  VAL n 
1 12  LEU n 
1 13  ALA n 
1 14  THR n 
1 15  VAL n 
1 16  SER n 
1 17  LYS n 
1 18  ILE n 
1 19  ASN n 
1 20  TYR n 
1 21  LYS n 
1 22  TYR n 
1 23  GLN n 
1 24  SER n 
1 25  VAL n 
1 26  GLU n 
1 27  VAL n 
1 28  LYS n 
1 29  VAL n 
1 30  ASN n 
1 31  ASN n 
1 32  LEU n 
1 33  THR n 
1 34  LEU n 
1 35  GLY n 
1 36  SER n 
1 37  ARG n 
1 38  ILE n 
1 39  GLY n 
1 40  ASP n 
1 41  ASP n 
1 42  GLY n 
1 43  SER n 
1 44  LEU n 
1 45  ALA n 
1 46  VAL n 
1 47  PRO n 
1 48  TYR n 
1 49  PRO n 
1 50  LYS n 
1 51  SER n 
1 52  PHE n 
1 53  ILE n 
1 54  GLY n 
1 55  ARG n 
1 56  THR n 
1 57  PRO n 
1 58  GLU n 
1 59  GLY n 
1 60  SER n 
1 61  VAL n 
1 62  PHE n 
1 63  GLY n 
1 64  THR n 
1 65  LYS n 
1 66  PRO n 
1 67  LEU n 
1 68  ILE n 
1 69  THR n 
1 70  GLU n 
1 71  GLY n 
1 72  SER n 
1 73  VAL n 
1 74  VAL n 
1 75  LEU n 
1 76  ILE n 
1 77  GLY n 
1 78  PHE n 
1 79  LEU n 
1 80  ASN n 
1 81  ASP n 
1 82  ASP n 
1 83  ILE n 
1 84  ASN n 
1 85  SER n 
1 86  PRO n 
1 87  ILE n 
1 88  ILE n 
1 89  LEU n 
1 90  SER n 
1 91  VAL n 
1 92  TYR n 
1 93  GLY n 
1 94  ASP n 
1 95  ASN n 
1 96  GLU n 
1 97  GLN n 
1 98  ASN n 
1 99  LYS n 
1 100 MET n 
1 101 ILE n 
1 102 ASN n 
1 103 THR n 
1 104 ASN n 
1 105 PRO n 
1 106 LEU n 
1 107 ASP n 
1 108 GLY n 
1 109 GLY n 
1 110 LYS n 
1 111 PHE n 
1 112 ASP n 
1 113 THR n 
1 114 GLU n 
1 115 SER n 
1 116 VAL n 
1 117 TYR n 
1 118 LYS n 
1 119 TYR n 
1 120 SER n 
1 121 SER n 
1 122 SER n 
1 123 LEU n 
1 124 TYR n 
1 125 GLU n 
1 126 ILE n 
1 127 LEU n 
1 128 PRO n 
1 129 SER n 
1 130 LEU n 
1 131 ASN n 
1 132 TYR n 
1 133 LYS n 
1 134 TYR n 
1 135 ASP n 
1 136 ASP n 
1 137 GLY n 
1 138 GLU n 
1 139 GLY n 
1 140 THR n 
1 141 SER n 
1 142 ILE n 
1 143 ARG n 
1 144 THR n 
1 145 TYR n 
1 146 ASN n 
1 147 GLY n 
1 148 LYS n 
1 149 SER n 
1 150 PHE n 
1 151 PHE n 
1 152 SER n 
1 153 MET n 
1 154 THR n 
1 155 SER n 
1 156 GLY n 
1 157 GLU n 
1 158 GLU n 
1 159 GLU n 
1 160 LYS n 
1 161 PRO n 
1 162 GLN n 
1 163 ALA n 
1 164 THR n 
1 165 ASP n 
1 166 PHE n 
1 167 TYR n 
1 168 THR n 
1 169 GLY n 
1 170 THR n 
1 171 GLU n 
1 172 TYR n 
1 173 GLN n 
1 174 ASP n 
1 175 LEU n 
1 176 PHE n 
1 177 THR n 
1 178 SER n 
1 179 TYR n 
1 180 TYR n 
1 181 GLY n 
1 182 ASN n 
1 183 LYS n 
1 184 THR n 
1 185 LEU n 
1 186 ILE n 
1 187 GLU n 
1 188 PRO n 
1 189 ARG n 
1 190 ILE n 
1 191 GLN n 
1 192 LYS n 
1 193 ALA n 
1 194 PRO n 
1 195 ASN n 
1 196 MET n 
1 197 LEU n 
1 198 PHE n 
1 199 LYS n 
1 200 HIS n 
1 201 GLN n 
1 202 GLY n 
1 203 VAL n 
1 204 PHE n 
1 205 TYR n 
1 206 ASP n 
1 207 ASP n 
1 208 GLY n 
1 209 THR n 
1 210 PRO n 
1 211 ASP n 
1 212 ASN n 
1 213 HIS n 
1 214 ILE n 
1 215 THR n 
1 216 THR n 
1 217 LEU n 
1 218 PHE n 
1 219 ILE n 
1 220 SER n 
1 221 GLU n 
1 222 ARG n 
1 223 GLY n 
1 224 ASP n 
1 225 ILE n 
1 226 ARG n 
1 227 ALA n 
1 228 SER n 
1 229 VAL n 
1 230 LEU n 
1 231 ASN n 
1 232 THR n 
1 233 GLU n 
1 234 THR n 
1 235 GLN n 
1 236 LYS n 
1 237 ARG n 
1 238 THR n 
1 239 THR n 
1 240 GLN n 
1 241 GLU n 
1 242 MET n 
1 243 SER n 
1 244 SER n 
1 245 ASP n 
1 246 GLY n 
1 247 SER n 
1 248 TYR n 
1 249 ARG n 
1 250 VAL n 
1 251 ILE n 
1 252 LYS n 
1 253 GLN n 
1 254 ASP n 
1 255 ASP n 
1 256 ASP n 
1 257 LEU n 
1 258 MET n 
1 259 LEU n 
1 260 ASP n 
1 261 GLU n 
1 262 ALA n 
1 263 GLN n 
1 264 VAL n 
1 265 TRP n 
1 266 ILE n 
1 267 GLU n 
1 268 TYR n 
1 269 GLY n 
1 270 ILE n 
1 271 SER n 
1 272 GLU n 
1 273 ASP n 
1 274 ASN n 
1 275 LYS n 
1 276 PHE n 
1 277 TYR n 
1 278 ILE n 
1 279 LYS n 
1 280 ASN n 
1 281 ASP n 
1 282 LYS n 
1 283 HIS n 
1 284 LYS n 
1 285 PHE n 
1 286 GLU n 
1 287 PHE n 
1 288 THR n 
1 289 ASP n 
1 290 GLU n 
1 291 GLY n 
1 292 ILE n 
1 293 TYR n 
1 294 ILE n 
1 295 ASP n 
1 296 ASP n 
1 297 LYS n 
1 298 PRO n 
1 299 MET n 
1 300 LEU n 
1 301 GLU n 
1 302 ASN n 
1 303 LEU n 
1 304 ASP n 
1 305 GLU n 
1 306 SER n 
1 307 ILE n 
1 308 ALA n 
1 309 GLU n 
1 310 ALA n 
1 311 MET n 
1 312 LYS n 
1 313 ASN n 
1 314 LEU n 
1 315 ASN n 
1 316 GLU n 
1 317 ILE n 
1 318 GLN n 
1 319 LYS n 
1 320 GLU n 
1 321 LEU n 
1 322 ASP n 
1 323 ASP n 
1 324 ILE n 
1 325 ASN n 
1 326 TYR n 
1 327 LEU n 
1 328 LEU n 
1 329 LYS n 
1 330 GLY n 
1 331 VAL n 
1 332 GLY n 
1 333 LYS n 
1 334 ASP n 
1 335 ASN n 
1 336 LEU n 
1 337 GLU n 
1 338 GLU n 
1 339 LEU n 
1 340 ILE n 
1 341 GLU n 
1 342 SER n 
1 343 THR n 
1 344 LYS n 
1 345 GLU n 
1 346 SER n 
1 347 ILE n 
1 348 GLU n 
1 349 ALA n 
1 350 SER n 
1 351 LYS n 
1 352 LYS n 
1 353 ALA n 
1 354 THR n 
1 355 SER n 
1 356 ASP n 
1 357 VAL n 
1 358 ASN n 
1 359 ARG n 
1 360 LEU n 
1 361 THR n 
1 362 THR n 
1 363 GLN n 
1 364 ILE n 
1 365 ALA n 
1 366 GLU n 
1 367 VAL n 
1 368 SER n 
1 369 GLY n 
1 370 ARG n 
1 371 THR n 
1 372 GLU n 
1 373 GLY n 
1 374 ILE n 
1 375 ILE n 
1 376 THR n 
1 377 GLN n 
1 378 PHE n 
1 379 GLN n 
1 380 LYS n 
1 381 PHE n 
1 382 ARG n 
1 383 ASP n 
1 384 GLU n 
1 385 THR n 
1 386 PHE n 
1 387 LYS n 
1 388 ASP n 
1 389 PHE n 
1 390 TYR n 
1 391 GLU n 
1 392 ASP n 
1 393 ALA n 
1 394 SER n 
1 395 THR n 
1 396 VAL n 
1 397 ILE n 
1 398 ASN n 
1 399 GLU n 
1 400 VAL n 
1 401 ASN n 
1 402 GLN n 
1 403 ASN n 
1 404 PHE n 
1 405 PRO n 
1 406 THR n 
1 407 MET n 
1 408 LYS n 
1 409 THR n 
1 410 ASP n 
1 411 VAL n 
1 412 LYS n 
1 413 THR n 
1 414 LEU n 
1 415 LYS n 
1 416 THR n 
1 417 LYS n 
1 418 VAL n 
1 419 ASP n 
1 420 ASN n 
1 421 LEU n 
1 422 GLU n 
1 423 LYS n 
1 424 THR n 
1 425 GLU n 
1 426 ILE n 
1 427 PRO n 
1 428 ASN n 
1 429 ILE n 
1 430 LYS n 
1 431 THR n 
1 432 ARG n 
1 433 LEU n 
1 434 THR n 
1 435 GLU n 
1 436 LEU n 
1 437 GLU n 
1 438 ASN n 
1 439 ASN n 
1 440 ASN n 
1 441 ASN n 
1 442 ASN n 
1 443 ALA n 
1 444 ASP n 
1 445 LYS n 
1 446 ILE n 
1 447 ILE n 
1 448 SER n 
1 449 ASP n 
1 450 ARG n 
1 451 GLY n 
1 452 GLU n 
1 453 HIS n 
1 454 ILE n 
1 455 GLY n 
1 456 ALA n 
1 457 MET n 
1 458 ILE n 
1 459 GLN n 
1 460 LEU n 
1 461 GLU n 
1 462 GLU n 
1 463 ASN n 
1 464 VAL n 
1 465 THR n 
1 466 VAL n 
1 467 PRO n 
1 468 MET n 
1 469 ARG n 
1 470 LYS n 
1 471 TYR n 
1 472 MET n 
1 473 PRO n 
1 474 ILE n 
1 475 PRO n 
1 476 TRP n 
1 477 SER n 
1 478 LYS n 
1 479 VAL n 
1 480 THR n 
1 481 TYR n 
1 482 ASN n 
1 483 ASN n 
1 484 ALA n 
1 485 GLU n 
1 486 PHE n 
1 487 TRP n 
1 488 ASP n 
1 489 SER n 
1 490 ASN n 
1 491 ASN n 
1 492 PRO n 
1 493 THR n 
1 494 ARG n 
1 495 LEU n 
1 496 VAL n 
1 497 VAL n 
1 498 PRO n 
1 499 LYS n 
1 500 GLY n 
1 501 ILE n 
1 502 THR n 
1 503 LYS n 
1 504 VAL n 
1 505 ARG n 
1 506 VAL n 
1 507 ALA n 
1 508 GLY n 
1 509 ASN n 
1 510 VAL n 
1 511 LEU n 
1 512 TRP n 
1 513 ASP n 
1 514 SER n 
1 515 ASN n 
1 516 ALA n 
1 517 THR n 
1 518 GLY n 
1 519 GLN n 
1 520 ARG n 
1 521 MET n 
1 522 LEU n 
1 523 ARG n 
1 524 ILE n 
1 525 LEU n 
1 526 LYS n 
1 527 ASN n 
1 528 GLY n 
1 529 THR n 
1 530 TYR n 
1 531 SER n 
1 532 ILE n 
1 533 GLY n 
1 534 LEU n 
1 535 PRO n 
1 536 TYR n 
1 537 THR n 
1 538 ARG n 
1 539 ASP n 
1 540 VAL n 
1 541 ALA n 
1 542 ILE n 
1 543 SER n 
1 544 THR n 
1 545 ALA n 
1 546 PRO n 
1 547 GLN n 
1 548 ASN n 
1 549 GLY n 
1 550 THR n 
1 551 SER n 
1 552 GLY n 
1 553 VAL n 
1 554 ILE n 
1 555 PRO n 
1 556 VAL n 
1 557 LYS n 
1 558 GLU n 
1 559 GLY n 
1 560 ASP n 
1 561 TYR n 
1 562 PHE n 
1 563 GLU n 
1 564 PHE n 
1 565 GLU n 
1 566 ALA n 
1 567 PHE n 
1 568 GLN n 
1 569 ASP n 
1 570 SER n 
1 571 GLU n 
1 572 GLY n 
1 573 ASP n 
1 574 ARG n 
1 575 GLN n 
1 576 PHE n 
1 577 ARG n 
1 578 ALA n 
1 579 ASP n 
1 580 PRO n 
1 581 TYR n 
1 582 THR n 
1 583 TRP n 
1 584 PHE n 
1 585 SER n 
1 586 ILE n 
1 587 GLU n 
1 588 ALA n 
1 589 ILE n 
1 590 GLU n 
1 591 LEU n 
1 592 GLU n 
1 593 THR n 
1 594 GLU n 
1 595 THR n 
1 596 MET n 
1 597 GLU n 
1 598 LYS n 
1 599 ASP n 
1 600 PHE n 
1 601 MET n 
1 602 LEU n 
1 603 ILE n 
1 604 GLY n 
1 605 HIS n 
1 606 ARG n 
1 607 GLY n 
1 608 ALA n 
1 609 THR n 
1 610 GLY n 
1 611 TYR n 
1 612 THR n 
1 613 ASP n 
1 614 GLU n 
1 615 HIS n 
1 616 THR n 
1 617 ILE n 
1 618 LYS n 
1 619 GLY n 
1 620 TYR n 
1 621 GLN n 
1 622 MET n 
1 623 ALA n 
1 624 LEU n 
1 625 ASP n 
1 626 LYS n 
1 627 GLY n 
1 628 ALA n 
1 629 ASP n 
1 630 TYR n 
1 631 ILE n 
1 632 GLU n 
1 633 LEU n 
1 634 ASP n 
1 635 LEU n 
1 636 GLN n 
1 637 LEU n 
1 638 THR n 
1 639 LYS n 
1 640 ASP n 
1 641 ASN n 
1 642 LYS n 
1 643 LEU n 
1 644 LEU n 
1 645 CYS n 
1 646 MET n 
1 647 HIS n 
1 648 ASP n 
1 649 SER n 
1 650 THR n 
1 651 ILE n 
1 652 ASP n 
1 653 ARG n 
1 654 THR n 
1 655 THR n 
1 656 THR n 
1 657 GLY n 
1 658 THR n 
1 659 GLY n 
1 660 LYS n 
1 661 VAL n 
1 662 GLY n 
1 663 ASP n 
1 664 MET n 
1 665 THR n 
1 666 LEU n 
1 667 SER n 
1 668 TYR n 
1 669 ILE n 
1 670 GLN n 
1 671 THR n 
1 672 ASN n 
1 673 PHE n 
1 674 THR n 
1 675 SER n 
1 676 LEU n 
1 677 ASN n 
1 678 GLY n 
1 679 GLU n 
1 680 PRO n 
1 681 ILE n 
1 682 PRO n 
1 683 SER n 
1 684 LEU n 
1 685 ASP n 
1 686 ASP n 
1 687 VAL n 
1 688 LEU n 
1 689 ASN n 
1 690 HIS n 
1 691 PHE n 
1 692 GLY n 
1 693 THR n 
1 694 LYS n 
1 695 VAL n 
1 696 LYS n 
1 697 TYR n 
1 698 TYR n 
1 699 ILE n 
1 700 GLU n 
1 701 THR n 
1 702 LYS n 
1 703 ARG n 
1 704 PRO n 
1 705 PHE n 
1 706 ASP n 
1 707 ALA n 
1 708 ASN n 
1 709 MET n 
1 710 ASP n 
1 711 ARG n 
1 712 GLU n 
1 713 LEU n 
1 714 LEU n 
1 715 THR n 
1 716 GLN n 
1 717 LEU n 
1 718 LYS n 
1 719 ALA n 
1 720 LYS n 
1 721 GLY n 
1 722 LEU n 
1 723 ILE n 
1 724 GLY n 
1 725 ILE n 
1 726 GLY n 
1 727 SER n 
1 728 GLU n 
1 729 ARG n 
1 730 PHE n 
1 731 GLN n 
1 732 VAL n 
1 733 ILE n 
1 734 ILE n 
1 735 GLN n 
1 736 SER n 
1 737 PHE n 
1 738 ALA n 
1 739 ARG n 
1 740 GLU n 
1 741 SER n 
1 742 LEU n 
1 743 ILE n 
1 744 ASN n 
1 745 ILE n 
1 746 HIS n 
1 747 ASN n 
1 748 GLN n 
1 749 PHE n 
1 750 SER n 
1 751 ASN n 
1 752 ILE n 
1 753 PRO n 
1 754 LEU n 
1 755 ALA n 
1 756 TYR n 
1 757 LEU n 
1 758 THR n 
1 759 SER n 
1 760 THR n 
1 761 PHE n 
1 762 SER n 
1 763 GLU n 
1 764 SER n 
1 765 GLU n 
1 766 MET n 
1 767 ASP n 
1 768 ASP n 
1 769 CYS n 
1 770 LEU n 
1 771 SER n 
1 772 TYR n 
1 773 GLY n 
1 774 PHE n 
1 775 TYR n 
1 776 ALA n 
1 777 ILE n 
1 778 ALA n 
1 779 PRO n 
1 780 LYS n 
1 781 TYR n 
1 782 THR n 
1 783 THR n 
1 784 ILE n 
1 785 THR n 
1 786 LYS n 
1 787 GLU n 
1 788 LEU n 
1 789 VAL n 
1 790 ASP n 
1 791 LEU n 
1 792 ALA n 
1 793 HIS n 
1 794 SER n 
1 795 LYS n 
1 796 GLY n 
1 797 LEU n 
1 798 LYS n 
1 799 VAL n 
1 800 HIS n 
1 801 ALA n 
1 802 TRP n 
1 803 THR n 
1 804 VAL n 
1 805 ASN n 
1 806 THR n 
1 807 LYS n 
1 808 GLU n 
1 809 GLU n 
1 810 MET n 
1 811 GLN n 
1 812 SER n 
1 813 LEU n 
1 814 ILE n 
1 815 GLN n 
1 816 MET n 
1 817 GLY n 
1 818 VAL n 
1 819 ASP n 
1 820 GLY n 
1 821 PHE n 
1 822 PHE n 
1 823 THR n 
1 824 ASN n 
1 825 TYR n 
1 826 LEU n 
1 827 ASP n 
1 828 GLU n 
1 829 TYR n 
1 830 LYS n 
1 831 LYS n 
1 832 ILE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   832 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 '812_115, 812a_115, 812F1_115, K1/420_115, K1_115' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Staphylococcus phage 812' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     307898 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   17  ?   ?   ?   A . n 
A 1 2   SER 2   18  ?   ?   ?   A . n 
A 1 3   ASP 3   19  ?   ?   ?   A . n 
A 1 4   ASP 4   20  ?   ?   ?   A . n 
A 1 5   LEU 5   21  ?   ?   ?   A . n 
A 1 6   ASN 6   22  ?   ?   ?   A . n 
A 1 7   VAL 7   23  ?   ?   ?   A . n 
A 1 8   LYS 8   24  ?   ?   ?   A . n 
A 1 9   GLY 9   25  ?   ?   ?   A . n 
A 1 10  LEU 10  26  ?   ?   ?   A . n 
A 1 11  VAL 11  27  ?   ?   ?   A . n 
A 1 12  LEU 12  28  ?   ?   ?   A . n 
A 1 13  ALA 13  29  ?   ?   ?   A . n 
A 1 14  THR 14  30  ?   ?   ?   A . n 
A 1 15  VAL 15  31  ?   ?   ?   A . n 
A 1 16  SER 16  32  ?   ?   ?   A . n 
A 1 17  LYS 17  33  ?   ?   ?   A . n 
A 1 18  ILE 18  34  ?   ?   ?   A . n 
A 1 19  ASN 19  35  ?   ?   ?   A . n 
A 1 20  TYR 20  36  ?   ?   ?   A . n 
A 1 21  LYS 21  37  ?   ?   ?   A . n 
A 1 22  TYR 22  38  ?   ?   ?   A . n 
A 1 23  GLN 23  39  ?   ?   ?   A . n 
A 1 24  SER 24  40  ?   ?   ?   A . n 
A 1 25  VAL 25  41  ?   ?   ?   A . n 
A 1 26  GLU 26  42  ?   ?   ?   A . n 
A 1 27  VAL 27  43  ?   ?   ?   A . n 
A 1 28  LYS 28  44  ?   ?   ?   A . n 
A 1 29  VAL 29  45  ?   ?   ?   A . n 
A 1 30  ASN 30  46  ?   ?   ?   A . n 
A 1 31  ASN 31  47  ?   ?   ?   A . n 
A 1 32  LEU 32  48  ?   ?   ?   A . n 
A 1 33  THR 33  49  ?   ?   ?   A . n 
A 1 34  LEU 34  50  ?   ?   ?   A . n 
A 1 35  GLY 35  51  ?   ?   ?   A . n 
A 1 36  SER 36  52  ?   ?   ?   A . n 
A 1 37  ARG 37  53  ?   ?   ?   A . n 
A 1 38  ILE 38  54  ?   ?   ?   A . n 
A 1 39  GLY 39  55  ?   ?   ?   A . n 
A 1 40  ASP 40  56  ?   ?   ?   A . n 
A 1 41  ASP 41  57  ?   ?   ?   A . n 
A 1 42  GLY 42  58  ?   ?   ?   A . n 
A 1 43  SER 43  59  ?   ?   ?   A . n 
A 1 44  LEU 44  60  ?   ?   ?   A . n 
A 1 45  ALA 45  61  ?   ?   ?   A . n 
A 1 46  VAL 46  62  ?   ?   ?   A . n 
A 1 47  PRO 47  63  ?   ?   ?   A . n 
A 1 48  TYR 48  64  ?   ?   ?   A . n 
A 1 49  PRO 49  65  ?   ?   ?   A . n 
A 1 50  LYS 50  66  ?   ?   ?   A . n 
A 1 51  SER 51  67  ?   ?   ?   A . n 
A 1 52  PHE 52  68  ?   ?   ?   A . n 
A 1 53  ILE 53  69  ?   ?   ?   A . n 
A 1 54  GLY 54  70  ?   ?   ?   A . n 
A 1 55  ARG 55  71  ?   ?   ?   A . n 
A 1 56  THR 56  72  ?   ?   ?   A . n 
A 1 57  PRO 57  73  ?   ?   ?   A . n 
A 1 58  GLU 58  74  ?   ?   ?   A . n 
A 1 59  GLY 59  75  ?   ?   ?   A . n 
A 1 60  SER 60  76  ?   ?   ?   A . n 
A 1 61  VAL 61  77  ?   ?   ?   A . n 
A 1 62  PHE 62  78  ?   ?   ?   A . n 
A 1 63  GLY 63  79  ?   ?   ?   A . n 
A 1 64  THR 64  80  ?   ?   ?   A . n 
A 1 65  LYS 65  81  ?   ?   ?   A . n 
A 1 66  PRO 66  82  ?   ?   ?   A . n 
A 1 67  LEU 67  83  ?   ?   ?   A . n 
A 1 68  ILE 68  84  ?   ?   ?   A . n 
A 1 69  THR 69  85  ?   ?   ?   A . n 
A 1 70  GLU 70  86  ?   ?   ?   A . n 
A 1 71  GLY 71  87  ?   ?   ?   A . n 
A 1 72  SER 72  88  ?   ?   ?   A . n 
A 1 73  VAL 73  89  ?   ?   ?   A . n 
A 1 74  VAL 74  90  ?   ?   ?   A . n 
A 1 75  LEU 75  91  ?   ?   ?   A . n 
A 1 76  ILE 76  92  ?   ?   ?   A . n 
A 1 77  GLY 77  93  ?   ?   ?   A . n 
A 1 78  PHE 78  94  ?   ?   ?   A . n 
A 1 79  LEU 79  95  ?   ?   ?   A . n 
A 1 80  ASN 80  96  ?   ?   ?   A . n 
A 1 81  ASP 81  97  ?   ?   ?   A . n 
A 1 82  ASP 82  98  ?   ?   ?   A . n 
A 1 83  ILE 83  99  ?   ?   ?   A . n 
A 1 84  ASN 84  100 ?   ?   ?   A . n 
A 1 85  SER 85  101 ?   ?   ?   A . n 
A 1 86  PRO 86  102 ?   ?   ?   A . n 
A 1 87  ILE 87  103 ?   ?   ?   A . n 
A 1 88  ILE 88  104 ?   ?   ?   A . n 
A 1 89  LEU 89  105 ?   ?   ?   A . n 
A 1 90  SER 90  106 ?   ?   ?   A . n 
A 1 91  VAL 91  107 ?   ?   ?   A . n 
A 1 92  TYR 92  108 ?   ?   ?   A . n 
A 1 93  GLY 93  109 ?   ?   ?   A . n 
A 1 94  ASP 94  110 ?   ?   ?   A . n 
A 1 95  ASN 95  111 ?   ?   ?   A . n 
A 1 96  GLU 96  112 ?   ?   ?   A . n 
A 1 97  GLN 97  113 ?   ?   ?   A . n 
A 1 98  ASN 98  114 ?   ?   ?   A . n 
A 1 99  LYS 99  115 ?   ?   ?   A . n 
A 1 100 MET 100 116 ?   ?   ?   A . n 
A 1 101 ILE 101 117 ?   ?   ?   A . n 
A 1 102 ASN 102 118 ?   ?   ?   A . n 
A 1 103 THR 103 119 ?   ?   ?   A . n 
A 1 104 ASN 104 120 ?   ?   ?   A . n 
A 1 105 PRO 105 121 ?   ?   ?   A . n 
A 1 106 LEU 106 122 ?   ?   ?   A . n 
A 1 107 ASP 107 123 ?   ?   ?   A . n 
A 1 108 GLY 108 124 ?   ?   ?   A . n 
A 1 109 GLY 109 125 ?   ?   ?   A . n 
A 1 110 LYS 110 126 ?   ?   ?   A . n 
A 1 111 PHE 111 127 ?   ?   ?   A . n 
A 1 112 ASP 112 128 ?   ?   ?   A . n 
A 1 113 THR 113 129 ?   ?   ?   A . n 
A 1 114 GLU 114 130 ?   ?   ?   A . n 
A 1 115 SER 115 131 ?   ?   ?   A . n 
A 1 116 VAL 116 132 ?   ?   ?   A . n 
A 1 117 TYR 117 133 ?   ?   ?   A . n 
A 1 118 LYS 118 134 ?   ?   ?   A . n 
A 1 119 TYR 119 135 ?   ?   ?   A . n 
A 1 120 SER 120 136 ?   ?   ?   A . n 
A 1 121 SER 121 137 ?   ?   ?   A . n 
A 1 122 SER 122 138 ?   ?   ?   A . n 
A 1 123 LEU 123 139 ?   ?   ?   A . n 
A 1 124 TYR 124 140 ?   ?   ?   A . n 
A 1 125 GLU 125 141 ?   ?   ?   A . n 
A 1 126 ILE 126 142 ?   ?   ?   A . n 
A 1 127 LEU 127 143 ?   ?   ?   A . n 
A 1 128 PRO 128 144 ?   ?   ?   A . n 
A 1 129 SER 129 145 ?   ?   ?   A . n 
A 1 130 LEU 130 146 ?   ?   ?   A . n 
A 1 131 ASN 131 147 ?   ?   ?   A . n 
A 1 132 TYR 132 148 ?   ?   ?   A . n 
A 1 133 LYS 133 149 ?   ?   ?   A . n 
A 1 134 TYR 134 150 ?   ?   ?   A . n 
A 1 135 ASP 135 151 ?   ?   ?   A . n 
A 1 136 ASP 136 152 ?   ?   ?   A . n 
A 1 137 GLY 137 153 ?   ?   ?   A . n 
A 1 138 GLU 138 154 ?   ?   ?   A . n 
A 1 139 GLY 139 155 ?   ?   ?   A . n 
A 1 140 THR 140 156 ?   ?   ?   A . n 
A 1 141 SER 141 157 ?   ?   ?   A . n 
A 1 142 ILE 142 158 ?   ?   ?   A . n 
A 1 143 ARG 143 159 ?   ?   ?   A . n 
A 1 144 THR 144 160 ?   ?   ?   A . n 
A 1 145 TYR 145 161 ?   ?   ?   A . n 
A 1 146 ASN 146 162 ?   ?   ?   A . n 
A 1 147 GLY 147 163 ?   ?   ?   A . n 
A 1 148 LYS 148 164 ?   ?   ?   A . n 
A 1 149 SER 149 165 ?   ?   ?   A . n 
A 1 150 PHE 150 166 ?   ?   ?   A . n 
A 1 151 PHE 151 167 ?   ?   ?   A . n 
A 1 152 SER 152 168 ?   ?   ?   A . n 
A 1 153 MET 153 169 ?   ?   ?   A . n 
A 1 154 THR 154 170 ?   ?   ?   A . n 
A 1 155 SER 155 171 ?   ?   ?   A . n 
A 1 156 GLY 156 172 ?   ?   ?   A . n 
A 1 157 GLU 157 173 ?   ?   ?   A . n 
A 1 158 GLU 158 174 ?   ?   ?   A . n 
A 1 159 GLU 159 175 ?   ?   ?   A . n 
A 1 160 LYS 160 176 ?   ?   ?   A . n 
A 1 161 PRO 161 177 ?   ?   ?   A . n 
A 1 162 GLN 162 178 ?   ?   ?   A . n 
A 1 163 ALA 163 179 ?   ?   ?   A . n 
A 1 164 THR 164 180 ?   ?   ?   A . n 
A 1 165 ASP 165 181 ?   ?   ?   A . n 
A 1 166 PHE 166 182 ?   ?   ?   A . n 
A 1 167 TYR 167 183 ?   ?   ?   A . n 
A 1 168 THR 168 184 ?   ?   ?   A . n 
A 1 169 GLY 169 185 ?   ?   ?   A . n 
A 1 170 THR 170 186 ?   ?   ?   A . n 
A 1 171 GLU 171 187 ?   ?   ?   A . n 
A 1 172 TYR 172 188 ?   ?   ?   A . n 
A 1 173 GLN 173 189 ?   ?   ?   A . n 
A 1 174 ASP 174 190 ?   ?   ?   A . n 
A 1 175 LEU 175 191 ?   ?   ?   A . n 
A 1 176 PHE 176 192 ?   ?   ?   A . n 
A 1 177 THR 177 193 ?   ?   ?   A . n 
A 1 178 SER 178 194 ?   ?   ?   A . n 
A 1 179 TYR 179 195 ?   ?   ?   A . n 
A 1 180 TYR 180 196 ?   ?   ?   A . n 
A 1 181 GLY 181 197 ?   ?   ?   A . n 
A 1 182 ASN 182 198 ?   ?   ?   A . n 
A 1 183 LYS 183 199 ?   ?   ?   A . n 
A 1 184 THR 184 200 ?   ?   ?   A . n 
A 1 185 LEU 185 201 ?   ?   ?   A . n 
A 1 186 ILE 186 202 ?   ?   ?   A . n 
A 1 187 GLU 187 203 ?   ?   ?   A . n 
A 1 188 PRO 188 204 ?   ?   ?   A . n 
A 1 189 ARG 189 205 ?   ?   ?   A . n 
A 1 190 ILE 190 206 ?   ?   ?   A . n 
A 1 191 GLN 191 207 ?   ?   ?   A . n 
A 1 192 LYS 192 208 ?   ?   ?   A . n 
A 1 193 ALA 193 209 ?   ?   ?   A . n 
A 1 194 PRO 194 210 ?   ?   ?   A . n 
A 1 195 ASN 195 211 ?   ?   ?   A . n 
A 1 196 MET 196 212 ?   ?   ?   A . n 
A 1 197 LEU 197 213 ?   ?   ?   A . n 
A 1 198 PHE 198 214 ?   ?   ?   A . n 
A 1 199 LYS 199 215 ?   ?   ?   A . n 
A 1 200 HIS 200 216 ?   ?   ?   A . n 
A 1 201 GLN 201 217 ?   ?   ?   A . n 
A 1 202 GLY 202 218 ?   ?   ?   A . n 
A 1 203 VAL 203 219 ?   ?   ?   A . n 
A 1 204 PHE 204 220 ?   ?   ?   A . n 
A 1 205 TYR 205 221 ?   ?   ?   A . n 
A 1 206 ASP 206 222 ?   ?   ?   A . n 
A 1 207 ASP 207 223 ?   ?   ?   A . n 
A 1 208 GLY 208 224 ?   ?   ?   A . n 
A 1 209 THR 209 225 ?   ?   ?   A . n 
A 1 210 PRO 210 226 ?   ?   ?   A . n 
A 1 211 ASP 211 227 ?   ?   ?   A . n 
A 1 212 ASN 212 228 ?   ?   ?   A . n 
A 1 213 HIS 213 229 ?   ?   ?   A . n 
A 1 214 ILE 214 230 ?   ?   ?   A . n 
A 1 215 THR 215 231 ?   ?   ?   A . n 
A 1 216 THR 216 232 ?   ?   ?   A . n 
A 1 217 LEU 217 233 ?   ?   ?   A . n 
A 1 218 PHE 218 234 ?   ?   ?   A . n 
A 1 219 ILE 219 235 ?   ?   ?   A . n 
A 1 220 SER 220 236 ?   ?   ?   A . n 
A 1 221 GLU 221 237 ?   ?   ?   A . n 
A 1 222 ARG 222 238 ?   ?   ?   A . n 
A 1 223 GLY 223 239 ?   ?   ?   A . n 
A 1 224 ASP 224 240 ?   ?   ?   A . n 
A 1 225 ILE 225 241 ?   ?   ?   A . n 
A 1 226 ARG 226 242 ?   ?   ?   A . n 
A 1 227 ALA 227 243 ?   ?   ?   A . n 
A 1 228 SER 228 244 ?   ?   ?   A . n 
A 1 229 VAL 229 245 ?   ?   ?   A . n 
A 1 230 LEU 230 246 ?   ?   ?   A . n 
A 1 231 ASN 231 247 ?   ?   ?   A . n 
A 1 232 THR 232 248 ?   ?   ?   A . n 
A 1 233 GLU 233 249 ?   ?   ?   A . n 
A 1 234 THR 234 250 ?   ?   ?   A . n 
A 1 235 GLN 235 251 ?   ?   ?   A . n 
A 1 236 LYS 236 252 ?   ?   ?   A . n 
A 1 237 ARG 237 253 ?   ?   ?   A . n 
A 1 238 THR 238 254 ?   ?   ?   A . n 
A 1 239 THR 239 255 ?   ?   ?   A . n 
A 1 240 GLN 240 256 ?   ?   ?   A . n 
A 1 241 GLU 241 257 ?   ?   ?   A . n 
A 1 242 MET 242 258 ?   ?   ?   A . n 
A 1 243 SER 243 259 ?   ?   ?   A . n 
A 1 244 SER 244 260 ?   ?   ?   A . n 
A 1 245 ASP 245 261 ?   ?   ?   A . n 
A 1 246 GLY 246 262 ?   ?   ?   A . n 
A 1 247 SER 247 263 ?   ?   ?   A . n 
A 1 248 TYR 248 264 ?   ?   ?   A . n 
A 1 249 ARG 249 265 ?   ?   ?   A . n 
A 1 250 VAL 250 266 ?   ?   ?   A . n 
A 1 251 ILE 251 267 ?   ?   ?   A . n 
A 1 252 LYS 252 268 ?   ?   ?   A . n 
A 1 253 GLN 253 269 ?   ?   ?   A . n 
A 1 254 ASP 254 270 ?   ?   ?   A . n 
A 1 255 ASP 255 271 ?   ?   ?   A . n 
A 1 256 ASP 256 272 ?   ?   ?   A . n 
A 1 257 LEU 257 273 ?   ?   ?   A . n 
A 1 258 MET 258 274 ?   ?   ?   A . n 
A 1 259 LEU 259 275 ?   ?   ?   A . n 
A 1 260 ASP 260 276 ?   ?   ?   A . n 
A 1 261 GLU 261 277 ?   ?   ?   A . n 
A 1 262 ALA 262 278 ?   ?   ?   A . n 
A 1 263 GLN 263 279 ?   ?   ?   A . n 
A 1 264 VAL 264 280 ?   ?   ?   A . n 
A 1 265 TRP 265 281 ?   ?   ?   A . n 
A 1 266 ILE 266 282 ?   ?   ?   A . n 
A 1 267 GLU 267 283 ?   ?   ?   A . n 
A 1 268 TYR 268 284 ?   ?   ?   A . n 
A 1 269 GLY 269 285 ?   ?   ?   A . n 
A 1 270 ILE 270 286 ?   ?   ?   A . n 
A 1 271 SER 271 287 ?   ?   ?   A . n 
A 1 272 GLU 272 288 ?   ?   ?   A . n 
A 1 273 ASP 273 289 ?   ?   ?   A . n 
A 1 274 ASN 274 290 ?   ?   ?   A . n 
A 1 275 LYS 275 291 ?   ?   ?   A . n 
A 1 276 PHE 276 292 ?   ?   ?   A . n 
A 1 277 TYR 277 293 ?   ?   ?   A . n 
A 1 278 ILE 278 294 ?   ?   ?   A . n 
A 1 279 LYS 279 295 ?   ?   ?   A . n 
A 1 280 ASN 280 296 ?   ?   ?   A . n 
A 1 281 ASP 281 297 ?   ?   ?   A . n 
A 1 282 LYS 282 298 ?   ?   ?   A . n 
A 1 283 HIS 283 299 ?   ?   ?   A . n 
A 1 284 LYS 284 300 ?   ?   ?   A . n 
A 1 285 PHE 285 301 ?   ?   ?   A . n 
A 1 286 GLU 286 302 ?   ?   ?   A . n 
A 1 287 PHE 287 303 ?   ?   ?   A . n 
A 1 288 THR 288 304 ?   ?   ?   A . n 
A 1 289 ASP 289 305 ?   ?   ?   A . n 
A 1 290 GLU 290 306 ?   ?   ?   A . n 
A 1 291 GLY 291 307 ?   ?   ?   A . n 
A 1 292 ILE 292 308 ?   ?   ?   A . n 
A 1 293 TYR 293 309 ?   ?   ?   A . n 
A 1 294 ILE 294 310 ?   ?   ?   A . n 
A 1 295 ASP 295 311 ?   ?   ?   A . n 
A 1 296 ASP 296 312 ?   ?   ?   A . n 
A 1 297 LYS 297 313 ?   ?   ?   A . n 
A 1 298 PRO 298 314 ?   ?   ?   A . n 
A 1 299 MET 299 315 ?   ?   ?   A . n 
A 1 300 LEU 300 316 ?   ?   ?   A . n 
A 1 301 GLU 301 317 ?   ?   ?   A . n 
A 1 302 ASN 302 318 ?   ?   ?   A . n 
A 1 303 LEU 303 319 ?   ?   ?   A . n 
A 1 304 ASP 304 320 ?   ?   ?   A . n 
A 1 305 GLU 305 321 ?   ?   ?   A . n 
A 1 306 SER 306 322 ?   ?   ?   A . n 
A 1 307 ILE 307 323 ?   ?   ?   A . n 
A 1 308 ALA 308 324 ?   ?   ?   A . n 
A 1 309 GLU 309 325 ?   ?   ?   A . n 
A 1 310 ALA 310 326 ?   ?   ?   A . n 
A 1 311 MET 311 327 ?   ?   ?   A . n 
A 1 312 LYS 312 328 ?   ?   ?   A . n 
A 1 313 ASN 313 329 ?   ?   ?   A . n 
A 1 314 LEU 314 330 ?   ?   ?   A . n 
A 1 315 ASN 315 331 ?   ?   ?   A . n 
A 1 316 GLU 316 332 ?   ?   ?   A . n 
A 1 317 ILE 317 333 ?   ?   ?   A . n 
A 1 318 GLN 318 334 ?   ?   ?   A . n 
A 1 319 LYS 319 335 ?   ?   ?   A . n 
A 1 320 GLU 320 336 ?   ?   ?   A . n 
A 1 321 LEU 321 337 ?   ?   ?   A . n 
A 1 322 ASP 322 338 ?   ?   ?   A . n 
A 1 323 ASP 323 339 ?   ?   ?   A . n 
A 1 324 ILE 324 340 ?   ?   ?   A . n 
A 1 325 ASN 325 341 ?   ?   ?   A . n 
A 1 326 TYR 326 342 ?   ?   ?   A . n 
A 1 327 LEU 327 343 ?   ?   ?   A . n 
A 1 328 LEU 328 344 ?   ?   ?   A . n 
A 1 329 LYS 329 345 ?   ?   ?   A . n 
A 1 330 GLY 330 346 ?   ?   ?   A . n 
A 1 331 VAL 331 347 ?   ?   ?   A . n 
A 1 332 GLY 332 348 ?   ?   ?   A . n 
A 1 333 LYS 333 349 ?   ?   ?   A . n 
A 1 334 ASP 334 350 ?   ?   ?   A . n 
A 1 335 ASN 335 351 ?   ?   ?   A . n 
A 1 336 LEU 336 352 ?   ?   ?   A . n 
A 1 337 GLU 337 353 ?   ?   ?   A . n 
A 1 338 GLU 338 354 ?   ?   ?   A . n 
A 1 339 LEU 339 355 ?   ?   ?   A . n 
A 1 340 ILE 340 356 ?   ?   ?   A . n 
A 1 341 GLU 341 357 ?   ?   ?   A . n 
A 1 342 SER 342 358 ?   ?   ?   A . n 
A 1 343 THR 343 359 ?   ?   ?   A . n 
A 1 344 LYS 344 360 ?   ?   ?   A . n 
A 1 345 GLU 345 361 ?   ?   ?   A . n 
A 1 346 SER 346 362 ?   ?   ?   A . n 
A 1 347 ILE 347 363 ?   ?   ?   A . n 
A 1 348 GLU 348 364 ?   ?   ?   A . n 
A 1 349 ALA 349 365 ?   ?   ?   A . n 
A 1 350 SER 350 366 ?   ?   ?   A . n 
A 1 351 LYS 351 367 ?   ?   ?   A . n 
A 1 352 LYS 352 368 ?   ?   ?   A . n 
A 1 353 ALA 353 369 ?   ?   ?   A . n 
A 1 354 THR 354 370 ?   ?   ?   A . n 
A 1 355 SER 355 371 ?   ?   ?   A . n 
A 1 356 ASP 356 372 ?   ?   ?   A . n 
A 1 357 VAL 357 373 ?   ?   ?   A . n 
A 1 358 ASN 358 374 ?   ?   ?   A . n 
A 1 359 ARG 359 375 ?   ?   ?   A . n 
A 1 360 LEU 360 376 ?   ?   ?   A . n 
A 1 361 THR 361 377 ?   ?   ?   A . n 
A 1 362 THR 362 378 ?   ?   ?   A . n 
A 1 363 GLN 363 379 ?   ?   ?   A . n 
A 1 364 ILE 364 380 ?   ?   ?   A . n 
A 1 365 ALA 365 381 ?   ?   ?   A . n 
A 1 366 GLU 366 382 ?   ?   ?   A . n 
A 1 367 VAL 367 383 ?   ?   ?   A . n 
A 1 368 SER 368 384 ?   ?   ?   A . n 
A 1 369 GLY 369 385 ?   ?   ?   A . n 
A 1 370 ARG 370 386 ?   ?   ?   A . n 
A 1 371 THR 371 387 ?   ?   ?   A . n 
A 1 372 GLU 372 388 ?   ?   ?   A . n 
A 1 373 GLY 373 389 ?   ?   ?   A . n 
A 1 374 ILE 374 390 ?   ?   ?   A . n 
A 1 375 ILE 375 391 ?   ?   ?   A . n 
A 1 376 THR 376 392 ?   ?   ?   A . n 
A 1 377 GLN 377 393 ?   ?   ?   A . n 
A 1 378 PHE 378 394 ?   ?   ?   A . n 
A 1 379 GLN 379 395 ?   ?   ?   A . n 
A 1 380 LYS 380 396 ?   ?   ?   A . n 
A 1 381 PHE 381 397 ?   ?   ?   A . n 
A 1 382 ARG 382 398 ?   ?   ?   A . n 
A 1 383 ASP 383 399 ?   ?   ?   A . n 
A 1 384 GLU 384 400 ?   ?   ?   A . n 
A 1 385 THR 385 401 ?   ?   ?   A . n 
A 1 386 PHE 386 402 ?   ?   ?   A . n 
A 1 387 LYS 387 403 ?   ?   ?   A . n 
A 1 388 ASP 388 404 ?   ?   ?   A . n 
A 1 389 PHE 389 405 ?   ?   ?   A . n 
A 1 390 TYR 390 406 ?   ?   ?   A . n 
A 1 391 GLU 391 407 ?   ?   ?   A . n 
A 1 392 ASP 392 408 ?   ?   ?   A . n 
A 1 393 ALA 393 409 ?   ?   ?   A . n 
A 1 394 SER 394 410 ?   ?   ?   A . n 
A 1 395 THR 395 411 ?   ?   ?   A . n 
A 1 396 VAL 396 412 ?   ?   ?   A . n 
A 1 397 ILE 397 413 ?   ?   ?   A . n 
A 1 398 ASN 398 414 ?   ?   ?   A . n 
A 1 399 GLU 399 415 ?   ?   ?   A . n 
A 1 400 VAL 400 416 ?   ?   ?   A . n 
A 1 401 ASN 401 417 ?   ?   ?   A . n 
A 1 402 GLN 402 418 ?   ?   ?   A . n 
A 1 403 ASN 403 419 ?   ?   ?   A . n 
A 1 404 PHE 404 420 ?   ?   ?   A . n 
A 1 405 PRO 405 421 ?   ?   ?   A . n 
A 1 406 THR 406 422 ?   ?   ?   A . n 
A 1 407 MET 407 423 ?   ?   ?   A . n 
A 1 408 LYS 408 424 ?   ?   ?   A . n 
A 1 409 THR 409 425 ?   ?   ?   A . n 
A 1 410 ASP 410 426 ?   ?   ?   A . n 
A 1 411 VAL 411 427 ?   ?   ?   A . n 
A 1 412 LYS 412 428 ?   ?   ?   A . n 
A 1 413 THR 413 429 ?   ?   ?   A . n 
A 1 414 LEU 414 430 ?   ?   ?   A . n 
A 1 415 LYS 415 431 ?   ?   ?   A . n 
A 1 416 THR 416 432 ?   ?   ?   A . n 
A 1 417 LYS 417 433 ?   ?   ?   A . n 
A 1 418 VAL 418 434 ?   ?   ?   A . n 
A 1 419 ASP 419 435 ?   ?   ?   A . n 
A 1 420 ASN 420 436 ?   ?   ?   A . n 
A 1 421 LEU 421 437 ?   ?   ?   A . n 
A 1 422 GLU 422 438 ?   ?   ?   A . n 
A 1 423 LYS 423 439 ?   ?   ?   A . n 
A 1 424 THR 424 440 ?   ?   ?   A . n 
A 1 425 GLU 425 441 ?   ?   ?   A . n 
A 1 426 ILE 426 442 ?   ?   ?   A . n 
A 1 427 PRO 427 443 ?   ?   ?   A . n 
A 1 428 ASN 428 444 ?   ?   ?   A . n 
A 1 429 ILE 429 445 ?   ?   ?   A . n 
A 1 430 LYS 430 446 ?   ?   ?   A . n 
A 1 431 THR 431 447 ?   ?   ?   A . n 
A 1 432 ARG 432 448 ?   ?   ?   A . n 
A 1 433 LEU 433 449 ?   ?   ?   A . n 
A 1 434 THR 434 450 ?   ?   ?   A . n 
A 1 435 GLU 435 451 ?   ?   ?   A . n 
A 1 436 LEU 436 452 ?   ?   ?   A . n 
A 1 437 GLU 437 453 ?   ?   ?   A . n 
A 1 438 ASN 438 454 ?   ?   ?   A . n 
A 1 439 ASN 439 455 ?   ?   ?   A . n 
A 1 440 ASN 440 456 ?   ?   ?   A . n 
A 1 441 ASN 441 457 ?   ?   ?   A . n 
A 1 442 ASN 442 458 ?   ?   ?   A . n 
A 1 443 ALA 443 459 ?   ?   ?   A . n 
A 1 444 ASP 444 460 ?   ?   ?   A . n 
A 1 445 LYS 445 461 ?   ?   ?   A . n 
A 1 446 ILE 446 462 ?   ?   ?   A . n 
A 1 447 ILE 447 463 ?   ?   ?   A . n 
A 1 448 SER 448 464 ?   ?   ?   A . n 
A 1 449 ASP 449 465 ?   ?   ?   A . n 
A 1 450 ARG 450 466 ?   ?   ?   A . n 
A 1 451 GLY 451 467 467 GLY GLY A . n 
A 1 452 GLU 452 468 468 GLU GLU A . n 
A 1 453 HIS 453 469 469 HIS HIS A . n 
A 1 454 ILE 454 470 470 ILE ILE A . n 
A 1 455 GLY 455 471 471 GLY GLY A . n 
A 1 456 ALA 456 472 472 ALA ALA A . n 
A 1 457 MET 457 473 473 MET MET A . n 
A 1 458 ILE 458 474 474 ILE ILE A . n 
A 1 459 GLN 459 475 475 GLN GLN A . n 
A 1 460 LEU 460 476 476 LEU LEU A . n 
A 1 461 GLU 461 477 477 GLU GLU A . n 
A 1 462 GLU 462 478 478 GLU GLU A . n 
A 1 463 ASN 463 479 479 ASN ASN A . n 
A 1 464 VAL 464 480 480 VAL VAL A . n 
A 1 465 THR 465 481 481 THR THR A . n 
A 1 466 VAL 466 482 482 VAL VAL A . n 
A 1 467 PRO 467 483 483 PRO PRO A . n 
A 1 468 MET 468 484 484 MET MET A . n 
A 1 469 ARG 469 485 485 ARG ARG A . n 
A 1 470 LYS 470 486 486 LYS LYS A . n 
A 1 471 TYR 471 487 487 TYR TYR A . n 
A 1 472 MET 472 488 488 MET MET A . n 
A 1 473 PRO 473 489 489 PRO PRO A . n 
A 1 474 ILE 474 490 490 ILE ILE A . n 
A 1 475 PRO 475 491 491 PRO PRO A . n 
A 1 476 TRP 476 492 492 TRP TRP A . n 
A 1 477 SER 477 493 493 SER SER A . n 
A 1 478 LYS 478 494 494 LYS LYS A . n 
A 1 479 VAL 479 495 495 VAL VAL A . n 
A 1 480 THR 480 496 496 THR THR A . n 
A 1 481 TYR 481 497 497 TYR TYR A . n 
A 1 482 ASN 482 498 498 ASN ASN A . n 
A 1 483 ASN 483 499 499 ASN ASN A . n 
A 1 484 ALA 484 500 500 ALA ALA A . n 
A 1 485 GLU 485 501 501 GLU GLU A . n 
A 1 486 PHE 486 502 502 PHE PHE A . n 
A 1 487 TRP 487 503 503 TRP TRP A . n 
A 1 488 ASP 488 504 504 ASP ASP A . n 
A 1 489 SER 489 505 505 SER SER A . n 
A 1 490 ASN 490 506 506 ASN ASN A . n 
A 1 491 ASN 491 507 507 ASN ASN A . n 
A 1 492 PRO 492 508 508 PRO PRO A . n 
A 1 493 THR 493 509 509 THR THR A . n 
A 1 494 ARG 494 510 510 ARG ARG A . n 
A 1 495 LEU 495 511 511 LEU LEU A . n 
A 1 496 VAL 496 512 512 VAL VAL A . n 
A 1 497 VAL 497 513 513 VAL VAL A . n 
A 1 498 PRO 498 514 514 PRO PRO A . n 
A 1 499 LYS 499 515 515 LYS LYS A . n 
A 1 500 GLY 500 516 516 GLY GLY A . n 
A 1 501 ILE 501 517 517 ILE ILE A . n 
A 1 502 THR 502 518 518 THR THR A . n 
A 1 503 LYS 503 519 519 LYS LYS A . n 
A 1 504 VAL 504 520 520 VAL VAL A . n 
A 1 505 ARG 505 521 521 ARG ARG A . n 
A 1 506 VAL 506 522 522 VAL VAL A . n 
A 1 507 ALA 507 523 523 ALA ALA A . n 
A 1 508 GLY 508 524 524 GLY GLY A . n 
A 1 509 ASN 509 525 525 ASN ASN A . n 
A 1 510 VAL 510 526 526 VAL VAL A . n 
A 1 511 LEU 511 527 527 LEU LEU A . n 
A 1 512 TRP 512 528 528 TRP TRP A . n 
A 1 513 ASP 513 529 529 ASP ASP A . n 
A 1 514 SER 514 530 530 SER SER A . n 
A 1 515 ASN 515 531 531 ASN ASN A . n 
A 1 516 ALA 516 532 532 ALA ALA A . n 
A 1 517 THR 517 533 533 THR THR A . n 
A 1 518 GLY 518 534 534 GLY GLY A . n 
A 1 519 GLN 519 535 535 GLN GLN A . n 
A 1 520 ARG 520 536 536 ARG ARG A . n 
A 1 521 MET 521 537 537 MET MET A . n 
A 1 522 LEU 522 538 538 LEU LEU A . n 
A 1 523 ARG 523 539 539 ARG ARG A . n 
A 1 524 ILE 524 540 540 ILE ILE A . n 
A 1 525 LEU 525 541 541 LEU LEU A . n 
A 1 526 LYS 526 542 542 LYS LYS A . n 
A 1 527 ASN 527 543 543 ASN ASN A . n 
A 1 528 GLY 528 544 544 GLY GLY A . n 
A 1 529 THR 529 545 545 THR THR A . n 
A 1 530 TYR 530 546 546 TYR TYR A . n 
A 1 531 SER 531 547 547 SER SER A . n 
A 1 532 ILE 532 548 548 ILE ILE A . n 
A 1 533 GLY 533 549 549 GLY GLY A . n 
A 1 534 LEU 534 550 550 LEU LEU A . n 
A 1 535 PRO 535 551 551 PRO PRO A . n 
A 1 536 TYR 536 552 552 TYR TYR A . n 
A 1 537 THR 537 553 553 THR THR A . n 
A 1 538 ARG 538 554 554 ARG ARG A . n 
A 1 539 ASP 539 555 555 ASP ASP A . n 
A 1 540 VAL 540 556 556 VAL VAL A . n 
A 1 541 ALA 541 557 557 ALA ALA A . n 
A 1 542 ILE 542 558 558 ILE ILE A . n 
A 1 543 SER 543 559 559 SER SER A . n 
A 1 544 THR 544 560 560 THR THR A . n 
A 1 545 ALA 545 561 561 ALA ALA A . n 
A 1 546 PRO 546 562 562 PRO PRO A . n 
A 1 547 GLN 547 563 563 GLN GLN A . n 
A 1 548 ASN 548 564 564 ASN ASN A . n 
A 1 549 GLY 549 565 565 GLY GLY A . n 
A 1 550 THR 550 566 566 THR THR A . n 
A 1 551 SER 551 567 567 SER SER A . n 
A 1 552 GLY 552 568 568 GLY GLY A . n 
A 1 553 VAL 553 569 569 VAL VAL A . n 
A 1 554 ILE 554 570 570 ILE ILE A . n 
A 1 555 PRO 555 571 571 PRO PRO A . n 
A 1 556 VAL 556 572 572 VAL VAL A . n 
A 1 557 LYS 557 573 573 LYS LYS A . n 
A 1 558 GLU 558 574 574 GLU GLU A . n 
A 1 559 GLY 559 575 575 GLY GLY A . n 
A 1 560 ASP 560 576 576 ASP ASP A . n 
A 1 561 TYR 561 577 577 TYR TYR A . n 
A 1 562 PHE 562 578 578 PHE PHE A . n 
A 1 563 GLU 563 579 579 GLU GLU A . n 
A 1 564 PHE 564 580 580 PHE PHE A . n 
A 1 565 GLU 565 581 581 GLU GLU A . n 
A 1 566 ALA 566 582 582 ALA ALA A . n 
A 1 567 PHE 567 583 583 PHE PHE A . n 
A 1 568 GLN 568 584 584 GLN GLN A . n 
A 1 569 ASP 569 585 585 ASP ASP A . n 
A 1 570 SER 570 586 586 SER SER A . n 
A 1 571 GLU 571 587 587 GLU GLU A . n 
A 1 572 GLY 572 588 588 GLY GLY A . n 
A 1 573 ASP 573 589 589 ASP ASP A . n 
A 1 574 ARG 574 590 590 ARG ARG A . n 
A 1 575 GLN 575 591 591 GLN GLN A . n 
A 1 576 PHE 576 592 592 PHE PHE A . n 
A 1 577 ARG 577 593 593 ARG ARG A . n 
A 1 578 ALA 578 594 594 ALA ALA A . n 
A 1 579 ASP 579 595 595 ASP ASP A . n 
A 1 580 PRO 580 596 596 PRO PRO A . n 
A 1 581 TYR 581 597 597 TYR TYR A . n 
A 1 582 THR 582 598 598 THR THR A . n 
A 1 583 TRP 583 599 599 TRP TRP A . n 
A 1 584 PHE 584 600 600 PHE PHE A . n 
A 1 585 SER 585 601 601 SER SER A . n 
A 1 586 ILE 586 602 602 ILE ILE A . n 
A 1 587 GLU 587 603 603 GLU GLU A . n 
A 1 588 ALA 588 604 604 ALA ALA A . n 
A 1 589 ILE 589 605 605 ILE ILE A . n 
A 1 590 GLU 590 606 606 GLU GLU A . n 
A 1 591 LEU 591 607 607 LEU LEU A . n 
A 1 592 GLU 592 608 608 GLU GLU A . n 
A 1 593 THR 593 609 609 THR THR A . n 
A 1 594 GLU 594 610 610 GLU GLU A . n 
A 1 595 THR 595 611 611 THR THR A . n 
A 1 596 MET 596 612 612 MET MET A . n 
A 1 597 GLU 597 613 613 GLU GLU A . n 
A 1 598 LYS 598 614 614 LYS LYS A . n 
A 1 599 ASP 599 615 615 ASP ASP A . n 
A 1 600 PHE 600 616 616 PHE PHE A . n 
A 1 601 MET 601 617 617 MET MET A . n 
A 1 602 LEU 602 618 618 LEU LEU A . n 
A 1 603 ILE 603 619 619 ILE ILE A . n 
A 1 604 GLY 604 620 620 GLY GLY A . n 
A 1 605 HIS 605 621 621 HIS HIS A . n 
A 1 606 ARG 606 622 622 ARG ARG A . n 
A 1 607 GLY 607 623 623 GLY GLY A . n 
A 1 608 ALA 608 624 624 ALA ALA A . n 
A 1 609 THR 609 625 625 THR THR A . n 
A 1 610 GLY 610 626 626 GLY GLY A . n 
A 1 611 TYR 611 627 627 TYR TYR A . n 
A 1 612 THR 612 628 628 THR THR A . n 
A 1 613 ASP 613 629 629 ASP ASP A . n 
A 1 614 GLU 614 630 630 GLU GLU A . n 
A 1 615 HIS 615 631 631 HIS HIS A . n 
A 1 616 THR 616 632 632 THR THR A . n 
A 1 617 ILE 617 633 633 ILE ILE A . n 
A 1 618 LYS 618 634 634 LYS LYS A . n 
A 1 619 GLY 619 635 635 GLY GLY A . n 
A 1 620 TYR 620 636 636 TYR TYR A . n 
A 1 621 GLN 621 637 637 GLN GLN A . n 
A 1 622 MET 622 638 638 MET MET A . n 
A 1 623 ALA 623 639 639 ALA ALA A . n 
A 1 624 LEU 624 640 640 LEU LEU A . n 
A 1 625 ASP 625 641 641 ASP ASP A . n 
A 1 626 LYS 626 642 642 LYS LYS A . n 
A 1 627 GLY 627 643 643 GLY GLY A . n 
A 1 628 ALA 628 644 644 ALA ALA A . n 
A 1 629 ASP 629 645 645 ASP ASP A . n 
A 1 630 TYR 630 646 646 TYR TYR A . n 
A 1 631 ILE 631 647 647 ILE ILE A . n 
A 1 632 GLU 632 648 648 GLU GLU A . n 
A 1 633 LEU 633 649 649 LEU LEU A . n 
A 1 634 ASP 634 650 650 ASP ASP A . n 
A 1 635 LEU 635 651 651 LEU LEU A . n 
A 1 636 GLN 636 652 652 GLN GLN A . n 
A 1 637 LEU 637 653 653 LEU LEU A . n 
A 1 638 THR 638 654 654 THR THR A . n 
A 1 639 LYS 639 655 655 LYS LYS A . n 
A 1 640 ASP 640 656 656 ASP ASP A . n 
A 1 641 ASN 641 657 657 ASN ASN A . n 
A 1 642 LYS 642 658 658 LYS LYS A . n 
A 1 643 LEU 643 659 659 LEU LEU A . n 
A 1 644 LEU 644 660 660 LEU LEU A . n 
A 1 645 CYS 645 661 661 CYS CYS A . n 
A 1 646 MET 646 662 662 MET MET A . n 
A 1 647 HIS 647 663 663 HIS HIS A . n 
A 1 648 ASP 648 664 664 ASP ASP A . n 
A 1 649 SER 649 665 665 SER SER A . n 
A 1 650 THR 650 666 666 THR THR A . n 
A 1 651 ILE 651 667 667 ILE ILE A . n 
A 1 652 ASP 652 668 668 ASP ASP A . n 
A 1 653 ARG 653 669 669 ARG ARG A . n 
A 1 654 THR 654 670 670 THR THR A . n 
A 1 655 THR 655 671 671 THR THR A . n 
A 1 656 THR 656 672 672 THR THR A . n 
A 1 657 GLY 657 673 673 GLY GLY A . n 
A 1 658 THR 658 674 674 THR THR A . n 
A 1 659 GLY 659 675 675 GLY GLY A . n 
A 1 660 LYS 660 676 676 LYS LYS A . n 
A 1 661 VAL 661 677 677 VAL VAL A . n 
A 1 662 GLY 662 678 678 GLY GLY A . n 
A 1 663 ASP 663 679 679 ASP ASP A . n 
A 1 664 MET 664 680 680 MET MET A . n 
A 1 665 THR 665 681 681 THR THR A . n 
A 1 666 LEU 666 682 682 LEU LEU A . n 
A 1 667 SER 667 683 683 SER SER A . n 
A 1 668 TYR 668 684 684 TYR TYR A . n 
A 1 669 ILE 669 685 685 ILE ILE A . n 
A 1 670 GLN 670 686 686 GLN GLN A . n 
A 1 671 THR 671 687 687 THR THR A . n 
A 1 672 ASN 672 688 688 ASN ASN A . n 
A 1 673 PHE 673 689 689 PHE PHE A . n 
A 1 674 THR 674 690 690 THR THR A . n 
A 1 675 SER 675 691 691 SER SER A . n 
A 1 676 LEU 676 692 692 LEU LEU A . n 
A 1 677 ASN 677 693 693 ASN ASN A . n 
A 1 678 GLY 678 694 694 GLY GLY A . n 
A 1 679 GLU 679 695 695 GLU GLU A . n 
A 1 680 PRO 680 696 696 PRO PRO A . n 
A 1 681 ILE 681 697 697 ILE ILE A . n 
A 1 682 PRO 682 698 698 PRO PRO A . n 
A 1 683 SER 683 699 699 SER SER A . n 
A 1 684 LEU 684 700 700 LEU LEU A . n 
A 1 685 ASP 685 701 701 ASP ASP A . n 
A 1 686 ASP 686 702 702 ASP ASP A . n 
A 1 687 VAL 687 703 703 VAL VAL A . n 
A 1 688 LEU 688 704 704 LEU LEU A . n 
A 1 689 ASN 689 705 705 ASN ASN A . n 
A 1 690 HIS 690 706 706 HIS HIS A . n 
A 1 691 PHE 691 707 707 PHE PHE A . n 
A 1 692 GLY 692 708 708 GLY GLY A . n 
A 1 693 THR 693 709 709 THR THR A . n 
A 1 694 LYS 694 710 710 LYS LYS A . n 
A 1 695 VAL 695 711 711 VAL VAL A . n 
A 1 696 LYS 696 712 712 LYS LYS A . n 
A 1 697 TYR 697 713 713 TYR TYR A . n 
A 1 698 TYR 698 714 714 TYR TYR A . n 
A 1 699 ILE 699 715 715 ILE ILE A . n 
A 1 700 GLU 700 716 716 GLU GLU A . n 
A 1 701 THR 701 717 717 THR THR A . n 
A 1 702 LYS 702 718 718 LYS LYS A . n 
A 1 703 ARG 703 719 719 ARG ARG A . n 
A 1 704 PRO 704 720 720 PRO PRO A . n 
A 1 705 PHE 705 721 721 PHE PHE A . n 
A 1 706 ASP 706 722 722 ASP ASP A . n 
A 1 707 ALA 707 723 723 ALA ALA A . n 
A 1 708 ASN 708 724 724 ASN ASN A . n 
A 1 709 MET 709 725 725 MET MET A . n 
A 1 710 ASP 710 726 726 ASP ASP A . n 
A 1 711 ARG 711 727 727 ARG ARG A . n 
A 1 712 GLU 712 728 728 GLU GLU A . n 
A 1 713 LEU 713 729 729 LEU LEU A . n 
A 1 714 LEU 714 730 730 LEU LEU A . n 
A 1 715 THR 715 731 731 THR THR A . n 
A 1 716 GLN 716 732 732 GLN GLN A . n 
A 1 717 LEU 717 733 733 LEU LEU A . n 
A 1 718 LYS 718 734 734 LYS LYS A . n 
A 1 719 ALA 719 735 735 ALA ALA A . n 
A 1 720 LYS 720 736 736 LYS LYS A . n 
A 1 721 GLY 721 737 737 GLY GLY A . n 
A 1 722 LEU 722 738 738 LEU LEU A . n 
A 1 723 ILE 723 739 739 ILE ILE A . n 
A 1 724 GLY 724 740 740 GLY GLY A . n 
A 1 725 ILE 725 741 741 ILE ILE A . n 
A 1 726 GLY 726 742 742 GLY GLY A . n 
A 1 727 SER 727 743 743 SER SER A . n 
A 1 728 GLU 728 744 744 GLU GLU A . n 
A 1 729 ARG 729 745 745 ARG ARG A . n 
A 1 730 PHE 730 746 746 PHE PHE A . n 
A 1 731 GLN 731 747 747 GLN GLN A . n 
A 1 732 VAL 732 748 748 VAL VAL A . n 
A 1 733 ILE 733 749 749 ILE ILE A . n 
A 1 734 ILE 734 750 750 ILE ILE A . n 
A 1 735 GLN 735 751 751 GLN GLN A . n 
A 1 736 SER 736 752 752 SER SER A . n 
A 1 737 PHE 737 753 753 PHE PHE A . n 
A 1 738 ALA 738 754 754 ALA ALA A . n 
A 1 739 ARG 739 755 755 ARG ARG A . n 
A 1 740 GLU 740 756 756 GLU GLU A . n 
A 1 741 SER 741 757 757 SER SER A . n 
A 1 742 LEU 742 758 758 LEU LEU A . n 
A 1 743 ILE 743 759 759 ILE ILE A . n 
A 1 744 ASN 744 760 760 ASN ASN A . n 
A 1 745 ILE 745 761 761 ILE ILE A . n 
A 1 746 HIS 746 762 762 HIS HIS A . n 
A 1 747 ASN 747 763 763 ASN ASN A . n 
A 1 748 GLN 748 764 764 GLN GLN A . n 
A 1 749 PHE 749 765 765 PHE PHE A . n 
A 1 750 SER 750 766 766 SER SER A . n 
A 1 751 ASN 751 767 767 ASN ASN A . n 
A 1 752 ILE 752 768 768 ILE ILE A . n 
A 1 753 PRO 753 769 769 PRO PRO A . n 
A 1 754 LEU 754 770 770 LEU LEU A . n 
A 1 755 ALA 755 771 771 ALA ALA A . n 
A 1 756 TYR 756 772 772 TYR TYR A . n 
A 1 757 LEU 757 773 773 LEU LEU A . n 
A 1 758 THR 758 774 774 THR THR A . n 
A 1 759 SER 759 775 775 SER SER A . n 
A 1 760 THR 760 776 776 THR THR A . n 
A 1 761 PHE 761 777 777 PHE PHE A . n 
A 1 762 SER 762 778 778 SER SER A . n 
A 1 763 GLU 763 779 779 GLU GLU A . n 
A 1 764 SER 764 780 780 SER SER A . n 
A 1 765 GLU 765 781 781 GLU GLU A . n 
A 1 766 MET 766 782 782 MET MET A . n 
A 1 767 ASP 767 783 783 ASP ASP A . n 
A 1 768 ASP 768 784 784 ASP ASP A . n 
A 1 769 CYS 769 785 785 CYS CYS A . n 
A 1 770 LEU 770 786 786 LEU LEU A . n 
A 1 771 SER 771 787 787 SER SER A . n 
A 1 772 TYR 772 788 788 TYR TYR A . n 
A 1 773 GLY 773 789 789 GLY GLY A . n 
A 1 774 PHE 774 790 790 PHE PHE A . n 
A 1 775 TYR 775 791 791 TYR TYR A . n 
A 1 776 ALA 776 792 792 ALA ALA A . n 
A 1 777 ILE 777 793 793 ILE ILE A . n 
A 1 778 ALA 778 794 794 ALA ALA A . n 
A 1 779 PRO 779 795 795 PRO PRO A . n 
A 1 780 LYS 780 796 796 LYS LYS A . n 
A 1 781 TYR 781 797 797 TYR TYR A . n 
A 1 782 THR 782 798 798 THR THR A . n 
A 1 783 THR 783 799 799 THR THR A . n 
A 1 784 ILE 784 800 800 ILE ILE A . n 
A 1 785 THR 785 801 801 THR THR A . n 
A 1 786 LYS 786 802 802 LYS LYS A . n 
A 1 787 GLU 787 803 803 GLU GLU A . n 
A 1 788 LEU 788 804 804 LEU LEU A . n 
A 1 789 VAL 789 805 805 VAL VAL A . n 
A 1 790 ASP 790 806 806 ASP ASP A . n 
A 1 791 LEU 791 807 807 LEU LEU A . n 
A 1 792 ALA 792 808 808 ALA ALA A . n 
A 1 793 HIS 793 809 809 HIS HIS A . n 
A 1 794 SER 794 810 810 SER SER A . n 
A 1 795 LYS 795 811 811 LYS LYS A . n 
A 1 796 GLY 796 812 812 GLY GLY A . n 
A 1 797 LEU 797 813 813 LEU LEU A . n 
A 1 798 LYS 798 814 814 LYS LYS A . n 
A 1 799 VAL 799 815 815 VAL VAL A . n 
A 1 800 HIS 800 816 816 HIS HIS A . n 
A 1 801 ALA 801 817 817 ALA ALA A . n 
A 1 802 TRP 802 818 818 TRP TRP A . n 
A 1 803 THR 803 819 819 THR THR A . n 
A 1 804 VAL 804 820 820 VAL VAL A . n 
A 1 805 ASN 805 821 821 ASN ASN A . n 
A 1 806 THR 806 822 822 THR THR A . n 
A 1 807 LYS 807 823 823 LYS LYS A . n 
A 1 808 GLU 808 824 824 GLU GLU A . n 
A 1 809 GLU 809 825 825 GLU GLU A . n 
A 1 810 MET 810 826 826 MET MET A . n 
A 1 811 GLN 811 827 827 GLN GLN A . n 
A 1 812 SER 812 828 828 SER SER A . n 
A 1 813 LEU 813 829 829 LEU LEU A . n 
A 1 814 ILE 814 830 830 ILE ILE A . n 
A 1 815 GLN 815 831 831 GLN GLN A . n 
A 1 816 MET 816 832 832 MET MET A . n 
A 1 817 GLY 817 833 833 GLY GLY A . n 
A 1 818 VAL 818 834 834 VAL VAL A . n 
A 1 819 ASP 819 835 835 ASP ASP A . n 
A 1 820 GLY 820 836 836 GLY GLY A . n 
A 1 821 PHE 821 837 837 PHE PHE A . n 
A 1 822 PHE 822 838 838 PHE PHE A . n 
A 1 823 THR 823 839 839 THR THR A . n 
A 1 824 ASN 824 840 840 ASN ASN A . n 
A 1 825 TYR 825 841 841 TYR TYR A . n 
A 1 826 LEU 826 842 842 LEU LEU A . n 
A 1 827 ASP 827 843 843 ASP ASP A . n 
A 1 828 GLU 828 844 844 GLU GLU A . n 
A 1 829 TYR 829 845 845 TYR TYR A . n 
A 1 830 LYS 830 846 846 LYS LYS A . n 
A 1 831 LYS 831 847 847 LYS LYS A . n 
A 1 832 ILE 832 848 848 ILE ILE A . n 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EUL 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9EUL 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.001 ? 9330  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.372 ? 12639 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.246 ? 3441  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.040 ? 1401  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 1626  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9EUL 
_struct.title                        
'Cryo-EM structure of Staphylococcus aureus bacteriophage phi812 central spike protein - knob and petal domains' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EUL 
_struct_keywords.text            'bacteriophage, phage, contractile, phi812, spike, central spike, TIM, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0U1WFD7_9CAUD 
_struct_ref.pdbx_db_accession          A0A0U1WFD7 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SDDLNVKGLVLATVSKINYKYQSVEVKVNNLTLGSRIGDDGSLAVPYPKSFIGRTPEGSVFGTKPLITEGSVVLIGFLND
DINSPIILSVYGDNEQNKMINTNPLDGGKFDTESVYKYSSSLYEILPSLNYKYDDGEGTSIRTYNGKSFFSMTSGEEEKP
QATDFYTGTEYQDLFTSYYGNKTLIEPRIQKAPNMLFKHQGVFYDDGTPDNHITTLFISERGDIRASVLNTETQKRTTQE
MSSDGSYRVIKQDDDLMLDEAQVWIEYGISEDNKFYIKNDKHKFEFTDEGIYIDDKPMLENLDESIAEAMKNLNEIQKEL
DDINYLLKGVGKDNLEELIESTKESIEASKKATSDVNRLTTQIAEVSGRTEGIITQFQKFRDETFKDFYEDASTVINEVN
QNFPTMKTDVKTLKTKVDNLEKTEIPNIKTRLTELENNNNNADKIISDRGEHIGAMIQLEENVTVPMRKYMPIPWSKVTY
NNAEFWDSNNPTRLVVPKGITKVRVAGNVLWDSNATGQRMLRILKNGTYSIGLPYTRDVAISTAPQNGTSGVIPVKEGDY
FEFEAFQDSEGDRQFRADPYTWFSIEAIELETETMEKDFMLIGHRGATGYTDEHTIKGYQMALDKGADYIELDLQLTKDN
KLLCMHDSTIDRTTTGTGKVGDMTLSYIQTNFTSLNGEPIPSLDDVLNHFGTKVKYYIETKRPFDANMDRELLTQLKAKG
LIGIGSERFQVIIQSFARESLINIHNQFSNIPLAYLTSTFSESEMDDCLSYGFYAIAPKYTTITKELVDLAHSKGLKVHA
WTVNTKEEMQSLIQMGVDGFFTNYLDEYKKI
;
_struct_ref.pdbx_align_begin           18 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9EUL 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 2 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 832 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A0U1WFD7 
_struct_ref_seq.db_align_beg                  18 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  848 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       18 
_struct_ref_seq.pdbx_auth_seq_align_end       848 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9EUL 
_struct_ref_seq_dif.mon_id                       GLY 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      1 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   A0A0U1WFD7 
_struct_ref_seq_dif.db_mon_id                    ? 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          ? 
_struct_ref_seq_dif.details                      'expression tag' 
_struct_ref_seq_dif.pdbx_auth_seq_num            17 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       'UCSF CHIMERA 1.16_b42360.' 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A 
1 2 A 
1 3 A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'       1_555 x,y,z 1.000000  0.000000  0.000000 0.00000   0.000000  1.000000  0.000000 0.00000   0.000000 
0.000000 1.000000 0.00000 
2 'point symmetry operation' ?     ?     -0.500000 -0.866025 0.000000 321.02230 0.866025  -0.500000 0.000000 86.01766  0.000000 
0.000000 1.000000 0.00000 
3 'point symmetry operation' ?     ?     -0.500000 0.866025  0.000000 86.01767  -0.866025 -0.500000 0.000000 321.02230 0.000000 
0.000000 1.000000 0.00000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ARG A 606 ? ALA A 608 ? ARG A 622 ALA A 624 5 ? 3  
HELX_P HELX_P2  AA2 THR A 616 ? GLY A 627 ? THR A 632 GLY A 643 1 ? 12 
HELX_P HELX_P3  AA3 LYS A 660 ? MET A 664 ? LYS A 676 MET A 680 5 ? 5  
HELX_P HELX_P4  AA4 THR A 665 ? PHE A 673 ? THR A 681 PHE A 689 1 ? 9  
HELX_P HELX_P5  AA5 SER A 683 ? GLY A 692 ? SER A 699 GLY A 708 1 ? 10 
HELX_P HELX_P6  AA6 THR A 693 ? VAL A 695 ? THR A 709 VAL A 711 5 ? 3  
HELX_P HELX_P7  AA7 ASP A 706 ? LYS A 720 ? ASP A 722 LYS A 736 1 ? 15 
HELX_P HELX_P8  AA8 GLU A 728 ? PHE A 730 ? GLU A 744 PHE A 746 5 ? 3  
HELX_P HELX_P9  AA9 ALA A 738 ? PHE A 749 ? ALA A 754 PHE A 765 1 ? 12 
HELX_P HELX_P10 AB1 SER A 762 ? GLY A 773 ? SER A 778 GLY A 789 1 ? 12 
HELX_P HELX_P11 AB2 TYR A 781 ? ILE A 784 ? TYR A 797 ILE A 800 5 ? 4  
HELX_P HELX_P12 AB3 THR A 785 ? GLY A 796 ? THR A 801 GLY A 812 1 ? 12 
HELX_P HELX_P13 AB4 THR A 806 ? GLY A 817 ? THR A 822 GLY A 833 1 ? 12 
HELX_P HELX_P14 AB5 LEU A 826 ? LYS A 830 ? LEU A 842 LYS A 846 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5  ? 
AA2 ? 5  ? 
AA3 ? 2  ? 
AA4 ? 4  ? 
AA5 ? 4  ? 
AA6 ? 10 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA1 4 5  ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? anti-parallel 
AA5 1 2  ? anti-parallel 
AA5 2 3  ? anti-parallel 
AA5 3 4  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA6 2 3  ? parallel      
AA6 3 4  ? parallel      
AA6 4 5  ? parallel      
AA6 5 6  ? parallel      
AA6 6 7  ? parallel      
AA6 7 8  ? parallel      
AA6 8 9  ? parallel      
AA6 9 10 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  LYS A 478 ? ASN A 482 ? LYS A 494 ASN A 498 
AA1 2  GLY A 455 ? GLN A 459 ? GLY A 471 GLN A 475 
AA1 3  TRP A 583 ? GLU A 590 ? TRP A 599 GLU A 606 
AA1 4  LYS A 503 ? VAL A 510 ? LYS A 519 VAL A 526 
AA1 5  GLN A 547 ? THR A 550 ? GLN A 563 THR A 566 
AA2 1  LYS A 478 ? ASN A 482 ? LYS A 494 ASN A 498 
AA2 2  GLY A 455 ? GLN A 459 ? GLY A 471 GLN A 475 
AA2 3  TRP A 583 ? GLU A 590 ? TRP A 599 GLU A 606 
AA2 4  LYS A 503 ? VAL A 510 ? LYS A 519 VAL A 526 
AA2 5  ILE A 554 ? PRO A 555 ? ILE A 570 PRO A 571 
AA3 1  VAL A 464 ? VAL A 466 ? VAL A 480 VAL A 482 
AA3 2  ARG A 574 ? PHE A 576 ? ARG A 590 PHE A 592 
AA4 1  MET A 472 ? PRO A 473 ? MET A 488 PRO A 489 
AA4 2  TYR A 561 ? GLN A 568 ? TYR A 577 GLN A 584 
AA4 3  ASN A 491 ? VAL A 496 ? ASN A 507 VAL A 512 
AA4 4  TRP A 487 ? ASP A 488 ? TRP A 503 ASP A 504 
AA5 1  MET A 472 ? PRO A 473 ? MET A 488 PRO A 489 
AA5 2  TYR A 561 ? GLN A 568 ? TYR A 577 GLN A 584 
AA5 3  GLN A 519 ? LYS A 526 ? GLN A 535 LYS A 542 
AA5 4  TYR A 536 ? VAL A 540 ? TYR A 552 VAL A 556 
AA6 1  LEU A 643 ? CYS A 645 ? LEU A 659 CYS A 661 
AA6 2  TYR A 630 ? LEU A 637 ? TYR A 646 LEU A 653 
AA6 3  TYR A 697 ? GLU A 700 ? TYR A 713 GLU A 716 
AA6 4  VAL A 732 ? SER A 736 ? VAL A 748 SER A 752 
AA6 5  LEU A 754 ? THR A 758 ? LEU A 770 THR A 774 
AA6 6  ALA A 776 ? PRO A 779 ? ALA A 792 PRO A 795 
AA6 7  LYS A 798 ? TRP A 802 ? LYS A 814 TRP A 818 
AA6 8  GLY A 820 ? THR A 823 ? GLY A 836 THR A 839 
AA6 9  MET A 601 ? GLY A 604 ? MET A 617 GLY A 620 
AA6 10 TYR A 630 ? LEU A 637 ? TYR A 646 LEU A 653 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O TYR A 481 ? O TYR A 497 N MET A 457 ? N MET A 473 
AA1 2 3  N ILE A 458 ? N ILE A 474 O PHE A 584 ? O PHE A 600 
AA1 3 4  O GLU A 587 ? O GLU A 603 N ARG A 505 ? N ARG A 521 
AA1 4 5  N GLY A 508 ? N GLY A 524 O GLY A 549 ? O GLY A 565 
AA2 1 2  O TYR A 481 ? O TYR A 497 N MET A 457 ? N MET A 473 
AA2 2 3  N ILE A 458 ? N ILE A 474 O PHE A 584 ? O PHE A 600 
AA2 3 4  O GLU A 587 ? O GLU A 603 N ARG A 505 ? N ARG A 521 
AA2 4 5  N VAL A 504 ? N VAL A 520 O ILE A 554 ? O ILE A 570 
AA3 1 2  N VAL A 464 ? N VAL A 480 O PHE A 576 ? O PHE A 592 
AA4 1 2  N MET A 472 ? N MET A 488 O ALA A 566 ? O ALA A 582 
AA4 2 3  O PHE A 562 ? O PHE A 578 N LEU A 495 ? N LEU A 511 
AA4 3 4  O ASN A 491 ? O ASN A 507 N ASP A 488 ? N ASP A 504 
AA5 1 2  N MET A 472 ? N MET A 488 O ALA A 566 ? O ALA A 582 
AA5 2 3  O GLU A 565 ? O GLU A 581 N ARG A 523 ? N ARG A 539 
AA5 3 4  N LEU A 522 ? N LEU A 538 O THR A 537 ? O THR A 553 
AA6 1 2  O LEU A 644 ? O LEU A 660 N GLN A 636 ? N GLN A 652 
AA6 2 3  N ILE A 631 ? N ILE A 647 O TYR A 698 ? O TYR A 714 
AA6 3 4  N ILE A 699 ? N ILE A 715 O GLN A 735 ? O GLN A 751 
AA6 4 5  N ILE A 734 ? N ILE A 750 O ALA A 755 ? O ALA A 771 
AA6 5 6  N TYR A 756 ? N TYR A 772 O ALA A 778 ? O ALA A 794 
AA6 6 7  N ILE A 777 ? N ILE A 793 O LYS A 798 ? O LYS A 814 
AA6 7 8  N ALA A 801 ? N ALA A 817 O GLY A 820 ? O GLY A 836 
AA6 8 9  O PHE A 821 ? O PHE A 837 N ILE A 603 ? N ILE A 619 
AA6 9 10 N GLY A 604 ? N GLY A 620 O TYR A 630 ? O TYR A 646 
# 
_pdbx_entry_details.entry_id                   9EUL 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PRO A 514 ? ? -67.83  -176.43 
2 1 SER A 559 ? ? 55.46   -129.80 
3 1 SER A 752 ? ? -171.17 142.44  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9EUL 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           'Chimera; Isolde' 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
loop_
_em_3d_fitting_list.id 
_em_3d_fitting_list.3d_fitting_id 
_em_3d_fitting_list.pdb_entry_id 
_em_3d_fitting_list.pdb_chain_id 
_em_3d_fitting_list.pdb_chain_residue_range 
_em_3d_fitting_list.details 
_em_3d_fitting_list.chain_id 
_em_3d_fitting_list.chain_residue_range 
_em_3d_fitting_list.source_name 
_em_3d_fitting_list.type 
_em_3d_fitting_list.accession_code 
_em_3d_fitting_list.initial_refinement_model_id 
1 1 . . . 'Xray structure'  ? ? Other 'experimental model' ? ? 
2 1 . . . 'manual building' ? ? Other 'in silico model'    ? ? 
# 
_em_3d_reconstruction.entry_id                    9EUL 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.23 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               135736 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       'sample diluted 10x with water before vitrification' 
_em_buffer.pH            7 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Central spike protein - knob and petal domains' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                9EUL 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        3710 
_em_image_scans.dimension_width         3838 
_em_image_scans.frames_per_image        40 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   1-40 
# 
_em_imaging.entry_id                        9EUL 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             300 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            70 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   200 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9EUL 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9EUL 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9EUL 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C3 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 17  ? A GLY 1   
2   1 Y 1 A SER 18  ? A SER 2   
3   1 Y 1 A ASP 19  ? A ASP 3   
4   1 Y 1 A ASP 20  ? A ASP 4   
5   1 Y 1 A LEU 21  ? A LEU 5   
6   1 Y 1 A ASN 22  ? A ASN 6   
7   1 Y 1 A VAL 23  ? A VAL 7   
8   1 Y 1 A LYS 24  ? A LYS 8   
9   1 Y 1 A GLY 25  ? A GLY 9   
10  1 Y 1 A LEU 26  ? A LEU 10  
11  1 Y 1 A VAL 27  ? A VAL 11  
12  1 Y 1 A LEU 28  ? A LEU 12  
13  1 Y 1 A ALA 29  ? A ALA 13  
14  1 Y 1 A THR 30  ? A THR 14  
15  1 Y 1 A VAL 31  ? A VAL 15  
16  1 Y 1 A SER 32  ? A SER 16  
17  1 Y 1 A LYS 33  ? A LYS 17  
18  1 Y 1 A ILE 34  ? A ILE 18  
19  1 Y 1 A ASN 35  ? A ASN 19  
20  1 Y 1 A TYR 36  ? A TYR 20  
21  1 Y 1 A LYS 37  ? A LYS 21  
22  1 Y 1 A TYR 38  ? A TYR 22  
23  1 Y 1 A GLN 39  ? A GLN 23  
24  1 Y 1 A SER 40  ? A SER 24  
25  1 Y 1 A VAL 41  ? A VAL 25  
26  1 Y 1 A GLU 42  ? A GLU 26  
27  1 Y 1 A VAL 43  ? A VAL 27  
28  1 Y 1 A LYS 44  ? A LYS 28  
29  1 Y 1 A VAL 45  ? A VAL 29  
30  1 Y 1 A ASN 46  ? A ASN 30  
31  1 Y 1 A ASN 47  ? A ASN 31  
32  1 Y 1 A LEU 48  ? A LEU 32  
33  1 Y 1 A THR 49  ? A THR 33  
34  1 Y 1 A LEU 50  ? A LEU 34  
35  1 Y 1 A GLY 51  ? A GLY 35  
36  1 Y 1 A SER 52  ? A SER 36  
37  1 Y 1 A ARG 53  ? A ARG 37  
38  1 Y 1 A ILE 54  ? A ILE 38  
39  1 Y 1 A GLY 55  ? A GLY 39  
40  1 Y 1 A ASP 56  ? A ASP 40  
41  1 Y 1 A ASP 57  ? A ASP 41  
42  1 Y 1 A GLY 58  ? A GLY 42  
43  1 Y 1 A SER 59  ? A SER 43  
44  1 Y 1 A LEU 60  ? A LEU 44  
45  1 Y 1 A ALA 61  ? A ALA 45  
46  1 Y 1 A VAL 62  ? A VAL 46  
47  1 Y 1 A PRO 63  ? A PRO 47  
48  1 Y 1 A TYR 64  ? A TYR 48  
49  1 Y 1 A PRO 65  ? A PRO 49  
50  1 Y 1 A LYS 66  ? A LYS 50  
51  1 Y 1 A SER 67  ? A SER 51  
52  1 Y 1 A PHE 68  ? A PHE 52  
53  1 Y 1 A ILE 69  ? A ILE 53  
54  1 Y 1 A GLY 70  ? A GLY 54  
55  1 Y 1 A ARG 71  ? A ARG 55  
56  1 Y 1 A THR 72  ? A THR 56  
57  1 Y 1 A PRO 73  ? A PRO 57  
58  1 Y 1 A GLU 74  ? A GLU 58  
59  1 Y 1 A GLY 75  ? A GLY 59  
60  1 Y 1 A SER 76  ? A SER 60  
61  1 Y 1 A VAL 77  ? A VAL 61  
62  1 Y 1 A PHE 78  ? A PHE 62  
63  1 Y 1 A GLY 79  ? A GLY 63  
64  1 Y 1 A THR 80  ? A THR 64  
65  1 Y 1 A LYS 81  ? A LYS 65  
66  1 Y 1 A PRO 82  ? A PRO 66  
67  1 Y 1 A LEU 83  ? A LEU 67  
68  1 Y 1 A ILE 84  ? A ILE 68  
69  1 Y 1 A THR 85  ? A THR 69  
70  1 Y 1 A GLU 86  ? A GLU 70  
71  1 Y 1 A GLY 87  ? A GLY 71  
72  1 Y 1 A SER 88  ? A SER 72  
73  1 Y 1 A VAL 89  ? A VAL 73  
74  1 Y 1 A VAL 90  ? A VAL 74  
75  1 Y 1 A LEU 91  ? A LEU 75  
76  1 Y 1 A ILE 92  ? A ILE 76  
77  1 Y 1 A GLY 93  ? A GLY 77  
78  1 Y 1 A PHE 94  ? A PHE 78  
79  1 Y 1 A LEU 95  ? A LEU 79  
80  1 Y 1 A ASN 96  ? A ASN 80  
81  1 Y 1 A ASP 97  ? A ASP 81  
82  1 Y 1 A ASP 98  ? A ASP 82  
83  1 Y 1 A ILE 99  ? A ILE 83  
84  1 Y 1 A ASN 100 ? A ASN 84  
85  1 Y 1 A SER 101 ? A SER 85  
86  1 Y 1 A PRO 102 ? A PRO 86  
87  1 Y 1 A ILE 103 ? A ILE 87  
88  1 Y 1 A ILE 104 ? A ILE 88  
89  1 Y 1 A LEU 105 ? A LEU 89  
90  1 Y 1 A SER 106 ? A SER 90  
91  1 Y 1 A VAL 107 ? A VAL 91  
92  1 Y 1 A TYR 108 ? A TYR 92  
93  1 Y 1 A GLY 109 ? A GLY 93  
94  1 Y 1 A ASP 110 ? A ASP 94  
95  1 Y 1 A ASN 111 ? A ASN 95  
96  1 Y 1 A GLU 112 ? A GLU 96  
97  1 Y 1 A GLN 113 ? A GLN 97  
98  1 Y 1 A ASN 114 ? A ASN 98  
99  1 Y 1 A LYS 115 ? A LYS 99  
100 1 Y 1 A MET 116 ? A MET 100 
101 1 Y 1 A ILE 117 ? A ILE 101 
102 1 Y 1 A ASN 118 ? A ASN 102 
103 1 Y 1 A THR 119 ? A THR 103 
104 1 Y 1 A ASN 120 ? A ASN 104 
105 1 Y 1 A PRO 121 ? A PRO 105 
106 1 Y 1 A LEU 122 ? A LEU 106 
107 1 Y 1 A ASP 123 ? A ASP 107 
108 1 Y 1 A GLY 124 ? A GLY 108 
109 1 Y 1 A GLY 125 ? A GLY 109 
110 1 Y 1 A LYS 126 ? A LYS 110 
111 1 Y 1 A PHE 127 ? A PHE 111 
112 1 Y 1 A ASP 128 ? A ASP 112 
113 1 Y 1 A THR 129 ? A THR 113 
114 1 Y 1 A GLU 130 ? A GLU 114 
115 1 Y 1 A SER 131 ? A SER 115 
116 1 Y 1 A VAL 132 ? A VAL 116 
117 1 Y 1 A TYR 133 ? A TYR 117 
118 1 Y 1 A LYS 134 ? A LYS 118 
119 1 Y 1 A TYR 135 ? A TYR 119 
120 1 Y 1 A SER 136 ? A SER 120 
121 1 Y 1 A SER 137 ? A SER 121 
122 1 Y 1 A SER 138 ? A SER 122 
123 1 Y 1 A LEU 139 ? A LEU 123 
124 1 Y 1 A TYR 140 ? A TYR 124 
125 1 Y 1 A GLU 141 ? A GLU 125 
126 1 Y 1 A ILE 142 ? A ILE 126 
127 1 Y 1 A LEU 143 ? A LEU 127 
128 1 Y 1 A PRO 144 ? A PRO 128 
129 1 Y 1 A SER 145 ? A SER 129 
130 1 Y 1 A LEU 146 ? A LEU 130 
131 1 Y 1 A ASN 147 ? A ASN 131 
132 1 Y 1 A TYR 148 ? A TYR 132 
133 1 Y 1 A LYS 149 ? A LYS 133 
134 1 Y 1 A TYR 150 ? A TYR 134 
135 1 Y 1 A ASP 151 ? A ASP 135 
136 1 Y 1 A ASP 152 ? A ASP 136 
137 1 Y 1 A GLY 153 ? A GLY 137 
138 1 Y 1 A GLU 154 ? A GLU 138 
139 1 Y 1 A GLY 155 ? A GLY 139 
140 1 Y 1 A THR 156 ? A THR 140 
141 1 Y 1 A SER 157 ? A SER 141 
142 1 Y 1 A ILE 158 ? A ILE 142 
143 1 Y 1 A ARG 159 ? A ARG 143 
144 1 Y 1 A THR 160 ? A THR 144 
145 1 Y 1 A TYR 161 ? A TYR 145 
146 1 Y 1 A ASN 162 ? A ASN 146 
147 1 Y 1 A GLY 163 ? A GLY 147 
148 1 Y 1 A LYS 164 ? A LYS 148 
149 1 Y 1 A SER 165 ? A SER 149 
150 1 Y 1 A PHE 166 ? A PHE 150 
151 1 Y 1 A PHE 167 ? A PHE 151 
152 1 Y 1 A SER 168 ? A SER 152 
153 1 Y 1 A MET 169 ? A MET 153 
154 1 Y 1 A THR 170 ? A THR 154 
155 1 Y 1 A SER 171 ? A SER 155 
156 1 Y 1 A GLY 172 ? A GLY 156 
157 1 Y 1 A GLU 173 ? A GLU 157 
158 1 Y 1 A GLU 174 ? A GLU 158 
159 1 Y 1 A GLU 175 ? A GLU 159 
160 1 Y 1 A LYS 176 ? A LYS 160 
161 1 Y 1 A PRO 177 ? A PRO 161 
162 1 Y 1 A GLN 178 ? A GLN 162 
163 1 Y 1 A ALA 179 ? A ALA 163 
164 1 Y 1 A THR 180 ? A THR 164 
165 1 Y 1 A ASP 181 ? A ASP 165 
166 1 Y 1 A PHE 182 ? A PHE 166 
167 1 Y 1 A TYR 183 ? A TYR 167 
168 1 Y 1 A THR 184 ? A THR 168 
169 1 Y 1 A GLY 185 ? A GLY 169 
170 1 Y 1 A THR 186 ? A THR 170 
171 1 Y 1 A GLU 187 ? A GLU 171 
172 1 Y 1 A TYR 188 ? A TYR 172 
173 1 Y 1 A GLN 189 ? A GLN 173 
174 1 Y 1 A ASP 190 ? A ASP 174 
175 1 Y 1 A LEU 191 ? A LEU 175 
176 1 Y 1 A PHE 192 ? A PHE 176 
177 1 Y 1 A THR 193 ? A THR 177 
178 1 Y 1 A SER 194 ? A SER 178 
179 1 Y 1 A TYR 195 ? A TYR 179 
180 1 Y 1 A TYR 196 ? A TYR 180 
181 1 Y 1 A GLY 197 ? A GLY 181 
182 1 Y 1 A ASN 198 ? A ASN 182 
183 1 Y 1 A LYS 199 ? A LYS 183 
184 1 Y 1 A THR 200 ? A THR 184 
185 1 Y 1 A LEU 201 ? A LEU 185 
186 1 Y 1 A ILE 202 ? A ILE 186 
187 1 Y 1 A GLU 203 ? A GLU 187 
188 1 Y 1 A PRO 204 ? A PRO 188 
189 1 Y 1 A ARG 205 ? A ARG 189 
190 1 Y 1 A ILE 206 ? A ILE 190 
191 1 Y 1 A GLN 207 ? A GLN 191 
192 1 Y 1 A LYS 208 ? A LYS 192 
193 1 Y 1 A ALA 209 ? A ALA 193 
194 1 Y 1 A PRO 210 ? A PRO 194 
195 1 Y 1 A ASN 211 ? A ASN 195 
196 1 Y 1 A MET 212 ? A MET 196 
197 1 Y 1 A LEU 213 ? A LEU 197 
198 1 Y 1 A PHE 214 ? A PHE 198 
199 1 Y 1 A LYS 215 ? A LYS 199 
200 1 Y 1 A HIS 216 ? A HIS 200 
201 1 Y 1 A GLN 217 ? A GLN 201 
202 1 Y 1 A GLY 218 ? A GLY 202 
203 1 Y 1 A VAL 219 ? A VAL 203 
204 1 Y 1 A PHE 220 ? A PHE 204 
205 1 Y 1 A TYR 221 ? A TYR 205 
206 1 Y 1 A ASP 222 ? A ASP 206 
207 1 Y 1 A ASP 223 ? A ASP 207 
208 1 Y 1 A GLY 224 ? A GLY 208 
209 1 Y 1 A THR 225 ? A THR 209 
210 1 Y 1 A PRO 226 ? A PRO 210 
211 1 Y 1 A ASP 227 ? A ASP 211 
212 1 Y 1 A ASN 228 ? A ASN 212 
213 1 Y 1 A HIS 229 ? A HIS 213 
214 1 Y 1 A ILE 230 ? A ILE 214 
215 1 Y 1 A THR 231 ? A THR 215 
216 1 Y 1 A THR 232 ? A THR 216 
217 1 Y 1 A LEU 233 ? A LEU 217 
218 1 Y 1 A PHE 234 ? A PHE 218 
219 1 Y 1 A ILE 235 ? A ILE 219 
220 1 Y 1 A SER 236 ? A SER 220 
221 1 Y 1 A GLU 237 ? A GLU 221 
222 1 Y 1 A ARG 238 ? A ARG 222 
223 1 Y 1 A GLY 239 ? A GLY 223 
224 1 Y 1 A ASP 240 ? A ASP 224 
225 1 Y 1 A ILE 241 ? A ILE 225 
226 1 Y 1 A ARG 242 ? A ARG 226 
227 1 Y 1 A ALA 243 ? A ALA 227 
228 1 Y 1 A SER 244 ? A SER 228 
229 1 Y 1 A VAL 245 ? A VAL 229 
230 1 Y 1 A LEU 246 ? A LEU 230 
231 1 Y 1 A ASN 247 ? A ASN 231 
232 1 Y 1 A THR 248 ? A THR 232 
233 1 Y 1 A GLU 249 ? A GLU 233 
234 1 Y 1 A THR 250 ? A THR 234 
235 1 Y 1 A GLN 251 ? A GLN 235 
236 1 Y 1 A LYS 252 ? A LYS 236 
237 1 Y 1 A ARG 253 ? A ARG 237 
238 1 Y 1 A THR 254 ? A THR 238 
239 1 Y 1 A THR 255 ? A THR 239 
240 1 Y 1 A GLN 256 ? A GLN 240 
241 1 Y 1 A GLU 257 ? A GLU 241 
242 1 Y 1 A MET 258 ? A MET 242 
243 1 Y 1 A SER 259 ? A SER 243 
244 1 Y 1 A SER 260 ? A SER 244 
245 1 Y 1 A ASP 261 ? A ASP 245 
246 1 Y 1 A GLY 262 ? A GLY 246 
247 1 Y 1 A SER 263 ? A SER 247 
248 1 Y 1 A TYR 264 ? A TYR 248 
249 1 Y 1 A ARG 265 ? A ARG 249 
250 1 Y 1 A VAL 266 ? A VAL 250 
251 1 Y 1 A ILE 267 ? A ILE 251 
252 1 Y 1 A LYS 268 ? A LYS 252 
253 1 Y 1 A GLN 269 ? A GLN 253 
254 1 Y 1 A ASP 270 ? A ASP 254 
255 1 Y 1 A ASP 271 ? A ASP 255 
256 1 Y 1 A ASP 272 ? A ASP 256 
257 1 Y 1 A LEU 273 ? A LEU 257 
258 1 Y 1 A MET 274 ? A MET 258 
259 1 Y 1 A LEU 275 ? A LEU 259 
260 1 Y 1 A ASP 276 ? A ASP 260 
261 1 Y 1 A GLU 277 ? A GLU 261 
262 1 Y 1 A ALA 278 ? A ALA 262 
263 1 Y 1 A GLN 279 ? A GLN 263 
264 1 Y 1 A VAL 280 ? A VAL 264 
265 1 Y 1 A TRP 281 ? A TRP 265 
266 1 Y 1 A ILE 282 ? A ILE 266 
267 1 Y 1 A GLU 283 ? A GLU 267 
268 1 Y 1 A TYR 284 ? A TYR 268 
269 1 Y 1 A GLY 285 ? A GLY 269 
270 1 Y 1 A ILE 286 ? A ILE 270 
271 1 Y 1 A SER 287 ? A SER 271 
272 1 Y 1 A GLU 288 ? A GLU 272 
273 1 Y 1 A ASP 289 ? A ASP 273 
274 1 Y 1 A ASN 290 ? A ASN 274 
275 1 Y 1 A LYS 291 ? A LYS 275 
276 1 Y 1 A PHE 292 ? A PHE 276 
277 1 Y 1 A TYR 293 ? A TYR 277 
278 1 Y 1 A ILE 294 ? A ILE 278 
279 1 Y 1 A LYS 295 ? A LYS 279 
280 1 Y 1 A ASN 296 ? A ASN 280 
281 1 Y 1 A ASP 297 ? A ASP 281 
282 1 Y 1 A LYS 298 ? A LYS 282 
283 1 Y 1 A HIS 299 ? A HIS 283 
284 1 Y 1 A LYS 300 ? A LYS 284 
285 1 Y 1 A PHE 301 ? A PHE 285 
286 1 Y 1 A GLU 302 ? A GLU 286 
287 1 Y 1 A PHE 303 ? A PHE 287 
288 1 Y 1 A THR 304 ? A THR 288 
289 1 Y 1 A ASP 305 ? A ASP 289 
290 1 Y 1 A GLU 306 ? A GLU 290 
291 1 Y 1 A GLY 307 ? A GLY 291 
292 1 Y 1 A ILE 308 ? A ILE 292 
293 1 Y 1 A TYR 309 ? A TYR 293 
294 1 Y 1 A ILE 310 ? A ILE 294 
295 1 Y 1 A ASP 311 ? A ASP 295 
296 1 Y 1 A ASP 312 ? A ASP 296 
297 1 Y 1 A LYS 313 ? A LYS 297 
298 1 Y 1 A PRO 314 ? A PRO 298 
299 1 Y 1 A MET 315 ? A MET 299 
300 1 Y 1 A LEU 316 ? A LEU 300 
301 1 Y 1 A GLU 317 ? A GLU 301 
302 1 Y 1 A ASN 318 ? A ASN 302 
303 1 Y 1 A LEU 319 ? A LEU 303 
304 1 Y 1 A ASP 320 ? A ASP 304 
305 1 Y 1 A GLU 321 ? A GLU 305 
306 1 Y 1 A SER 322 ? A SER 306 
307 1 Y 1 A ILE 323 ? A ILE 307 
308 1 Y 1 A ALA 324 ? A ALA 308 
309 1 Y 1 A GLU 325 ? A GLU 309 
310 1 Y 1 A ALA 326 ? A ALA 310 
311 1 Y 1 A MET 327 ? A MET 311 
312 1 Y 1 A LYS 328 ? A LYS 312 
313 1 Y 1 A ASN 329 ? A ASN 313 
314 1 Y 1 A LEU 330 ? A LEU 314 
315 1 Y 1 A ASN 331 ? A ASN 315 
316 1 Y 1 A GLU 332 ? A GLU 316 
317 1 Y 1 A ILE 333 ? A ILE 317 
318 1 Y 1 A GLN 334 ? A GLN 318 
319 1 Y 1 A LYS 335 ? A LYS 319 
320 1 Y 1 A GLU 336 ? A GLU 320 
321 1 Y 1 A LEU 337 ? A LEU 321 
322 1 Y 1 A ASP 338 ? A ASP 322 
323 1 Y 1 A ASP 339 ? A ASP 323 
324 1 Y 1 A ILE 340 ? A ILE 324 
325 1 Y 1 A ASN 341 ? A ASN 325 
326 1 Y 1 A TYR 342 ? A TYR 326 
327 1 Y 1 A LEU 343 ? A LEU 327 
328 1 Y 1 A LEU 344 ? A LEU 328 
329 1 Y 1 A LYS 345 ? A LYS 329 
330 1 Y 1 A GLY 346 ? A GLY 330 
331 1 Y 1 A VAL 347 ? A VAL 331 
332 1 Y 1 A GLY 348 ? A GLY 332 
333 1 Y 1 A LYS 349 ? A LYS 333 
334 1 Y 1 A ASP 350 ? A ASP 334 
335 1 Y 1 A ASN 351 ? A ASN 335 
336 1 Y 1 A LEU 352 ? A LEU 336 
337 1 Y 1 A GLU 353 ? A GLU 337 
338 1 Y 1 A GLU 354 ? A GLU 338 
339 1 Y 1 A LEU 355 ? A LEU 339 
340 1 Y 1 A ILE 356 ? A ILE 340 
341 1 Y 1 A GLU 357 ? A GLU 341 
342 1 Y 1 A SER 358 ? A SER 342 
343 1 Y 1 A THR 359 ? A THR 343 
344 1 Y 1 A LYS 360 ? A LYS 344 
345 1 Y 1 A GLU 361 ? A GLU 345 
346 1 Y 1 A SER 362 ? A SER 346 
347 1 Y 1 A ILE 363 ? A ILE 347 
348 1 Y 1 A GLU 364 ? A GLU 348 
349 1 Y 1 A ALA 365 ? A ALA 349 
350 1 Y 1 A SER 366 ? A SER 350 
351 1 Y 1 A LYS 367 ? A LYS 351 
352 1 Y 1 A LYS 368 ? A LYS 352 
353 1 Y 1 A ALA 369 ? A ALA 353 
354 1 Y 1 A THR 370 ? A THR 354 
355 1 Y 1 A SER 371 ? A SER 355 
356 1 Y 1 A ASP 372 ? A ASP 356 
357 1 Y 1 A VAL 373 ? A VAL 357 
358 1 Y 1 A ASN 374 ? A ASN 358 
359 1 Y 1 A ARG 375 ? A ARG 359 
360 1 Y 1 A LEU 376 ? A LEU 360 
361 1 Y 1 A THR 377 ? A THR 361 
362 1 Y 1 A THR 378 ? A THR 362 
363 1 Y 1 A GLN 379 ? A GLN 363 
364 1 Y 1 A ILE 380 ? A ILE 364 
365 1 Y 1 A ALA 381 ? A ALA 365 
366 1 Y 1 A GLU 382 ? A GLU 366 
367 1 Y 1 A VAL 383 ? A VAL 367 
368 1 Y 1 A SER 384 ? A SER 368 
369 1 Y 1 A GLY 385 ? A GLY 369 
370 1 Y 1 A ARG 386 ? A ARG 370 
371 1 Y 1 A THR 387 ? A THR 371 
372 1 Y 1 A GLU 388 ? A GLU 372 
373 1 Y 1 A GLY 389 ? A GLY 373 
374 1 Y 1 A ILE 390 ? A ILE 374 
375 1 Y 1 A ILE 391 ? A ILE 375 
376 1 Y 1 A THR 392 ? A THR 376 
377 1 Y 1 A GLN 393 ? A GLN 377 
378 1 Y 1 A PHE 394 ? A PHE 378 
379 1 Y 1 A GLN 395 ? A GLN 379 
380 1 Y 1 A LYS 396 ? A LYS 380 
381 1 Y 1 A PHE 397 ? A PHE 381 
382 1 Y 1 A ARG 398 ? A ARG 382 
383 1 Y 1 A ASP 399 ? A ASP 383 
384 1 Y 1 A GLU 400 ? A GLU 384 
385 1 Y 1 A THR 401 ? A THR 385 
386 1 Y 1 A PHE 402 ? A PHE 386 
387 1 Y 1 A LYS 403 ? A LYS 387 
388 1 Y 1 A ASP 404 ? A ASP 388 
389 1 Y 1 A PHE 405 ? A PHE 389 
390 1 Y 1 A TYR 406 ? A TYR 390 
391 1 Y 1 A GLU 407 ? A GLU 391 
392 1 Y 1 A ASP 408 ? A ASP 392 
393 1 Y 1 A ALA 409 ? A ALA 393 
394 1 Y 1 A SER 410 ? A SER 394 
395 1 Y 1 A THR 411 ? A THR 395 
396 1 Y 1 A VAL 412 ? A VAL 396 
397 1 Y 1 A ILE 413 ? A ILE 397 
398 1 Y 1 A ASN 414 ? A ASN 398 
399 1 Y 1 A GLU 415 ? A GLU 399 
400 1 Y 1 A VAL 416 ? A VAL 400 
401 1 Y 1 A ASN 417 ? A ASN 401 
402 1 Y 1 A GLN 418 ? A GLN 402 
403 1 Y 1 A ASN 419 ? A ASN 403 
404 1 Y 1 A PHE 420 ? A PHE 404 
405 1 Y 1 A PRO 421 ? A PRO 405 
406 1 Y 1 A THR 422 ? A THR 406 
407 1 Y 1 A MET 423 ? A MET 407 
408 1 Y 1 A LYS 424 ? A LYS 408 
409 1 Y 1 A THR 425 ? A THR 409 
410 1 Y 1 A ASP 426 ? A ASP 410 
411 1 Y 1 A VAL 427 ? A VAL 411 
412 1 Y 1 A LYS 428 ? A LYS 412 
413 1 Y 1 A THR 429 ? A THR 413 
414 1 Y 1 A LEU 430 ? A LEU 414 
415 1 Y 1 A LYS 431 ? A LYS 415 
416 1 Y 1 A THR 432 ? A THR 416 
417 1 Y 1 A LYS 433 ? A LYS 417 
418 1 Y 1 A VAL 434 ? A VAL 418 
419 1 Y 1 A ASP 435 ? A ASP 419 
420 1 Y 1 A ASN 436 ? A ASN 420 
421 1 Y 1 A LEU 437 ? A LEU 421 
422 1 Y 1 A GLU 438 ? A GLU 422 
423 1 Y 1 A LYS 439 ? A LYS 423 
424 1 Y 1 A THR 440 ? A THR 424 
425 1 Y 1 A GLU 441 ? A GLU 425 
426 1 Y 1 A ILE 442 ? A ILE 426 
427 1 Y 1 A PRO 443 ? A PRO 427 
428 1 Y 1 A ASN 444 ? A ASN 428 
429 1 Y 1 A ILE 445 ? A ILE 429 
430 1 Y 1 A LYS 446 ? A LYS 430 
431 1 Y 1 A THR 447 ? A THR 431 
432 1 Y 1 A ARG 448 ? A ARG 432 
433 1 Y 1 A LEU 449 ? A LEU 433 
434 1 Y 1 A THR 450 ? A THR 434 
435 1 Y 1 A GLU 451 ? A GLU 435 
436 1 Y 1 A LEU 452 ? A LEU 436 
437 1 Y 1 A GLU 453 ? A GLU 437 
438 1 Y 1 A ASN 454 ? A ASN 438 
439 1 Y 1 A ASN 455 ? A ASN 439 
440 1 Y 1 A ASN 456 ? A ASN 440 
441 1 Y 1 A ASN 457 ? A ASN 441 
442 1 Y 1 A ASN 458 ? A ASN 442 
443 1 Y 1 A ALA 459 ? A ALA 443 
444 1 Y 1 A ASP 460 ? A ASP 444 
445 1 Y 1 A LYS 461 ? A LYS 445 
446 1 Y 1 A ILE 462 ? A ILE 446 
447 1 Y 1 A ILE 463 ? A ILE 447 
448 1 Y 1 A SER 464 ? A SER 448 
449 1 Y 1 A ASP 465 ? A ASP 449 
450 1 Y 1 A ARG 466 ? A ARG 450 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-27 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9EUL 
_em_admin.last_update        2025-04-09 
_em_admin.map_release_date   2025-04-09 
_em_admin.title              
'Cryo-EM structure of Staphylococcus aureus bacteriophage phi812 central spike protein - knob and petal domains' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 50  mM KNaO4P- 1 'Sodium Potassium Phosphate' 
1 200 mM NaCl    2 'Sodium Chloride'            
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          307898 
_em_entity_assembly_naturalsource.organism             'Staphylococcus phage 812' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               8 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         57 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     3120 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Quantum LS' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   487160 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? crYOLO         ?       
'IMAGE ACQUISITION'        ? 2  ? ? 1 SerialEM       ?       
MASKING                    ? 3  ? ? ? ?              ?       
'CTF CORRECTION'           ? 4  1 ? ? Gctf           ?       
'LAYERLINE INDEXING'       ? 5  ? ? ? ?              ?       
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?              ?       
'MODEL FITTING'            ? 7  ? 1 ? 'UCSF Chimera' 1.15    
OTHER                      ? 8  ? ? ? ?              ?       
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? RELION         3.1     
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? RELION         5.0beta 
CLASSIFICATION             ? 11 1 ? ? RELION         5.0beta 
RECONSTRUCTION             ? 12 1 ? ? RELION         5.0beta 
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX         1.21    
# 
_em_specimen.concentration           0.8 
_em_specimen.details                 'sample diluted 10x with water before vitrification' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'European Research Council (ERC)' 'European Union' 101043452   1 
'Other government'                'Czech Republic' LX22NP05103 2 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
1 'experimental model' Other ? 
2 'in silico model'    Other ? 
# 
_atom_sites.entry_id                    9EUL 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLY A 1 451 ? 140.962 134.312 129.091 1.00 54.91  ? 467 GLY A N   1 
ATOM 2    C CA  . GLY A 1 451 ? 141.734 135.581 129.214 1.00 54.57  ? 467 GLY A CA  1 
ATOM 3    C C   . GLY A 1 451 ? 142.889 135.462 130.188 1.00 55.06  ? 467 GLY A C   1 
ATOM 4    O O   . GLY A 1 451 ? 143.358 134.361 130.477 1.00 50.79  ? 467 GLY A O   1 
ATOM 5    N N   . GLU A 1 452 ? 143.348 136.603 130.698 1.00 49.82  ? 468 GLU A N   1 
ATOM 6    C CA  . GLU A 1 452 ? 144.447 136.653 131.649 1.00 47.66  ? 468 GLU A CA  1 
ATOM 7    C C   . GLU A 1 452 ? 144.014 137.441 132.876 1.00 41.21  ? 468 GLU A C   1 
ATOM 8    O O   . GLU A 1 452 ? 143.260 138.413 132.773 1.00 44.16  ? 468 GLU A O   1 
ATOM 9    C CB  . GLU A 1 452 ? 145.696 137.291 131.027 1.00 50.00  ? 468 GLU A CB  1 
ATOM 10   C CG  . GLU A 1 452 ? 146.922 137.243 131.922 1.00 49.59  ? 468 GLU A CG  1 
ATOM 11   C CD  . GLU A 1 452 ? 148.172 137.745 131.229 1.00 55.09  ? 468 GLU A CD  1 
ATOM 12   O OE1 . GLU A 1 452 ? 148.078 138.159 130.054 1.00 55.87  ? 468 GLU A OE1 1 
ATOM 13   O OE2 . GLU A 1 452 ? 149.250 137.725 131.859 1.00 56.70  ? 468 GLU A OE2 1 
ATOM 14   N N   . HIS A 1 453 ? 144.498 137.013 134.039 1.00 29.43  ? 469 HIS A N   1 
ATOM 15   C CA  . HIS A 1 453 ? 144.107 137.637 135.295 1.00 20.08  ? 469 HIS A CA  1 
ATOM 16   C C   . HIS A 1 453 ? 144.658 139.055 135.384 1.00 28.64  ? 469 HIS A C   1 
ATOM 17   O O   . HIS A 1 453 ? 145.803 139.313 135.000 1.00 41.53  ? 469 HIS A O   1 
ATOM 18   C CB  . HIS A 1 453 ? 144.604 136.804 136.475 1.00 28.22  ? 469 HIS A CB  1 
ATOM 19   C CG  . HIS A 1 453 ? 144.274 137.394 137.811 1.00 23.68  ? 469 HIS A CG  1 
ATOM 20   N ND1 . HIS A 1 453 ? 145.235 137.912 138.653 1.00 21.17  ? 469 HIS A ND1 1 
ATOM 21   C CD2 . HIS A 1 453 ? 143.090 137.553 138.448 1.00 28.31  ? 469 HIS A CD2 1 
ATOM 22   C CE1 . HIS A 1 453 ? 144.657 138.361 139.753 1.00 29.48  ? 469 HIS A CE1 1 
ATOM 23   N NE2 . HIS A 1 453 ? 143.356 138.156 139.653 1.00 37.24  ? 469 HIS A NE2 1 
ATOM 24   N N   . ILE A 1 454 ? 143.837 139.971 135.890 1.00 31.25  ? 470 ILE A N   1 
ATOM 25   C CA  . ILE A 1 454 ? 144.228 141.358 136.119 1.00 19.78  ? 470 ILE A CA  1 
ATOM 26   C C   . ILE A 1 454 ? 144.032 141.652 137.599 1.00 14.64  ? 470 ILE A C   1 
ATOM 27   O O   . ILE A 1 454 ? 142.913 141.552 138.119 1.00 27.85  ? 470 ILE A O   1 
ATOM 28   C CB  . ILE A 1 454 ? 143.419 142.331 135.248 1.00 23.19  ? 470 ILE A CB  1 
ATOM 29   C CG1 . ILE A 1 454 ? 143.675 142.046 133.766 1.00 28.70  ? 470 ILE A CG1 1 
ATOM 30   C CG2 . ILE A 1 454 ? 143.777 143.774 135.589 1.00 23.76  ? 470 ILE A CG2 1 
ATOM 31   C CD1 . ILE A 1 454 ? 142.758 142.797 132.825 1.00 31.26  ? 470 ILE A CD1 1 
ATOM 32   N N   . GLY A 1 455 ? 145.113 142.017 138.274 1.00 20.73  ? 471 GLY A N   1 
ATOM 33   C CA  . GLY A 1 455 ? 145.052 142.294 139.694 1.00 15.70  ? 471 GLY A CA  1 
ATOM 34   C C   . GLY A 1 455 ? 146.448 142.407 140.268 1.00 22.94  ? 471 GLY A C   1 
ATOM 35   O O   . GLY A 1 455 ? 147.447 142.399 139.543 1.00 36.25  ? 471 GLY A O   1 
ATOM 36   N N   . ALA A 1 456 ? 146.496 142.514 141.593 1.00 13.18  ? 472 ALA A N   1 
ATOM 37   C CA  . ALA A 1 456 ? 147.765 142.635 142.292 1.00 10.46  ? 472 ALA A CA  1 
ATOM 38   C C   . ALA A 1 456 ? 147.608 142.141 143.721 1.00 7.64   ? 472 ALA A C   1 
ATOM 39   O O   . ALA A 1 456 ? 146.507 142.115 144.277 1.00 21.26  ? 472 ALA A O   1 
ATOM 40   C CB  . ALA A 1 456 ? 148.275 144.079 142.284 1.00 23.45  ? 472 ALA A CB  1 
ATOM 41   N N   . MET A 1 457 ? 148.736 141.749 144.309 1.00 14.25  ? 473 MET A N   1 
ATOM 42   C CA  . MET A 1 457 ? 148.795 141.329 145.702 1.00 20.91  ? 473 MET A CA  1 
ATOM 43   C C   . MET A 1 457 ? 150.096 141.840 146.298 1.00 7.80   ? 473 MET A C   1 
ATOM 44   O O   . MET A 1 457 ? 151.148 141.757 145.656 1.00 14.62  ? 473 MET A O   1 
ATOM 45   C CB  . MET A 1 457 ? 148.714 139.804 145.833 1.00 25.61  ? 473 MET A CB  1 
ATOM 46   C CG  . MET A 1 457 ? 148.756 139.302 147.269 1.00 14.18  ? 473 MET A CG  1 
ATOM 47   S SD  . MET A 1 457 ? 148.643 137.506 147.394 1.00 32.14  ? 473 MET A SD  1 
ATOM 48   C CE  . MET A 1 457 ? 146.977 137.226 146.801 1.00 27.70  ? 473 MET A CE  1 
ATOM 49   N N   . ILE A 1 458 ? 150.025 142.363 147.518 1.00 8.85   ? 474 ILE A N   1 
ATOM 50   C CA  . ILE A 1 458 ? 151.184 142.921 148.197 1.00 3.58   ? 474 ILE A CA  1 
ATOM 51   C C   . ILE A 1 458 ? 151.271 142.324 149.593 1.00 17.48  ? 474 ILE A C   1 
ATOM 52   O O   . ILE A 1 458 ? 150.271 141.877 150.164 1.00 32.30  ? 474 ILE A O   1 
ATOM 53   C CB  . ILE A 1 458 ? 151.121 144.463 148.264 1.00 9.76   ? 474 ILE A CB  1 
ATOM 54   C CG1 . ILE A 1 458 ? 149.898 144.914 149.063 1.00 21.81  ? 474 ILE A CG1 1 
ATOM 55   C CG2 . ILE A 1 458 ? 151.079 145.046 146.863 1.00 17.91  ? 474 ILE A CG2 1 
ATOM 56   C CD1 . ILE A 1 458 ? 149.693 146.412 149.070 1.00 20.97  ? 474 ILE A CD1 1 
ATOM 57   N N   . GLN A 1 459 ? 152.483 142.319 150.142 1.00 23.62  ? 475 GLN A N   1 
ATOM 58   C CA  . GLN A 1 459 ? 152.735 141.744 151.453 1.00 27.50  ? 475 GLN A CA  1 
ATOM 59   C C   . GLN A 1 459 ? 153.879 142.500 152.112 1.00 37.54  ? 475 GLN A C   1 
ATOM 60   O O   . GLN A 1 459 ? 154.651 143.202 151.454 1.00 43.51  ? 475 GLN A O   1 
ATOM 61   C CB  . GLN A 1 459 ? 153.059 140.249 151.354 1.00 21.09  ? 475 GLN A CB  1 
ATOM 62   C CG  . GLN A 1 459 ? 154.214 139.932 150.416 1.00 38.75  ? 475 GLN A CG  1 
ATOM 63   C CD  . GLN A 1 459 ? 154.499 138.446 150.311 1.00 42.18  ? 475 GLN A CD  1 
ATOM 64   O OE1 . GLN A 1 459 ? 154.713 137.921 149.218 1.00 34.99  ? 475 GLN A OE1 1 
ATOM 65   N NE2 . GLN A 1 459 ? 154.513 137.761 151.449 1.00 44.29  ? 475 GLN A NE2 1 
ATOM 66   N N   . LEU A 1 460 ? 153.978 142.349 153.428 1.00 41.91  ? 476 LEU A N   1 
ATOM 67   C CA  . LEU A 1 460 ? 155.019 143.002 154.205 1.00 45.16  ? 476 LEU A CA  1 
ATOM 68   C C   . LEU A 1 460 ? 156.302 142.183 154.181 1.00 46.00  ? 476 LEU A C   1 
ATOM 69   O O   . LEU A 1 460 ? 156.280 140.956 154.049 1.00 45.36  ? 476 LEU A O   1 
ATOM 70   C CB  . LEU A 1 460 ? 154.568 143.201 155.653 1.00 45.22  ? 476 LEU A CB  1 
ATOM 71   C CG  . LEU A 1 460 ? 153.503 144.270 155.898 1.00 41.19  ? 476 LEU A CG  1 
ATOM 72   C CD1 . LEU A 1 460 ? 152.950 144.145 157.305 1.00 50.89  ? 476 LEU A CD1 1 
ATOM 73   C CD2 . LEU A 1 460 ? 154.072 145.661 155.672 1.00 41.01  ? 476 LEU A CD2 1 
ATOM 74   N N   . GLU A 1 461 ? 157.430 142.884 154.308 1.00 51.62  ? 477 GLU A N   1 
ATOM 75   C CA  . GLU A 1 461 ? 158.730 142.247 154.449 1.00 56.23  ? 477 GLU A CA  1 
ATOM 76   C C   . GLU A 1 461 ? 159.303 142.369 155.853 1.00 60.24  ? 477 GLU A C   1 
ATOM 77   O O   . GLU A 1 461 ? 160.148 141.551 156.230 1.00 60.72  ? 477 GLU A O   1 
ATOM 78   C CB  . GLU A 1 461 ? 159.728 142.847 153.448 1.00 52.45  ? 477 GLU A CB  1 
ATOM 79   C CG  . GLU A 1 461 ? 161.030 142.073 153.331 1.00 55.04  ? 477 GLU A CG  1 
ATOM 80   C CD  . GLU A 1 461 ? 161.931 142.615 152.239 1.00 66.51  ? 477 GLU A CD  1 
ATOM 81   O OE1 . GLU A 1 461 ? 161.558 143.625 151.605 1.00 66.09  ? 477 GLU A OE1 1 
ATOM 82   O OE2 . GLU A 1 461 ? 163.012 142.030 152.013 1.00 66.30  ? 477 GLU A OE2 1 
ATOM 83   N N   . GLU A 1 462 ? 158.866 143.360 156.627 1.00 58.11  ? 478 GLU A N   1 
ATOM 84   C CA  . GLU A 1 462 ? 159.257 143.505 158.021 1.00 55.38  ? 478 GLU A CA  1 
ATOM 85   C C   . GLU A 1 462 ? 158.018 143.809 158.849 1.00 58.09  ? 478 GLU A C   1 
ATOM 86   O O   . GLU A 1 462 ? 157.084 144.465 158.379 1.00 53.13  ? 478 GLU A O   1 
ATOM 87   C CB  . GLU A 1 462 ? 160.302 144.612 158.206 1.00 55.69  ? 478 GLU A CB  1 
ATOM 88   C CG  . GLU A 1 462 ? 161.622 144.336 157.508 1.00 58.68  ? 478 GLU A CG  1 
ATOM 89   C CD  . GLU A 1 462 ? 162.639 145.439 157.725 1.00 63.42  ? 478 GLU A CD  1 
ATOM 90   O OE1 . GLU A 1 462 ? 162.296 146.445 158.382 1.00 59.88  ? 478 GLU A OE1 1 
ATOM 91   O OE2 . GLU A 1 462 ? 163.781 145.301 157.240 1.00 62.95  ? 478 GLU A OE2 1 
ATOM 92   N N   . ASN A 1 463 ? 158.019 143.326 160.089 1.00 51.58  ? 479 ASN A N   1 
ATOM 93   C CA  . ASN A 1 463 ? 156.855 143.480 160.951 1.00 47.95  ? 479 ASN A CA  1 
ATOM 94   C C   . ASN A 1 463 ? 156.587 144.952 161.239 1.00 46.72  ? 479 ASN A C   1 
ATOM 95   O O   . ASN A 1 463 ? 157.513 145.728 161.493 1.00 50.44  ? 479 ASN A O   1 
ATOM 96   C CB  . ASN A 1 463 ? 157.063 142.716 162.257 1.00 45.22  ? 479 ASN A CB  1 
ATOM 97   C CG  . ASN A 1 463 ? 157.306 141.237 162.035 1.00 48.85  ? 479 ASN A CG  1 
ATOM 98   O OD1 . ASN A 1 463 ? 156.940 140.685 160.998 1.00 54.09  ? 479 ASN A OD1 1 
ATOM 99   N ND2 . ASN A 1 463 ? 157.923 140.586 163.013 1.00 47.98  ? 479 ASN A ND2 1 
ATOM 100  N N   . VAL A 1 464 ? 155.313 145.331 161.197 1.00 46.05  ? 480 VAL A N   1 
ATOM 101  C CA  . VAL A 1 464 ? 154.898 146.695 161.505 1.00 50.70  ? 480 VAL A CA  1 
ATOM 102  C C   . VAL A 1 464 ? 154.347 146.741 162.923 1.00 54.97  ? 480 VAL A C   1 
ATOM 103  O O   . VAL A 1 464 ? 153.661 145.815 163.372 1.00 52.63  ? 480 VAL A O   1 
ATOM 104  C CB  . VAL A 1 464 ? 153.858 147.187 160.483 1.00 41.72  ? 480 VAL A CB  1 
ATOM 105  C CG1 . VAL A 1 464 ? 153.286 148.532 160.906 1.00 48.35  ? 480 VAL A CG1 1 
ATOM 106  C CG2 . VAL A 1 464 ? 154.478 147.281 159.099 1.00 41.47  ? 480 VAL A CG2 1 
ATOM 107  N N   . THR A 1 465 ? 154.647 147.824 163.635 1.00 66.26  ? 481 THR A N   1 
ATOM 108  C CA  . THR A 1 465 ? 154.223 148.008 165.017 1.00 66.15  ? 481 THR A CA  1 
ATOM 109  C C   . THR A 1 465 ? 152.976 148.882 165.038 1.00 60.45  ? 481 THR A C   1 
ATOM 110  O O   . THR A 1 465 ? 152.980 149.989 164.489 1.00 62.98  ? 481 THR A O   1 
ATOM 111  C CB  . THR A 1 465 ? 155.337 148.643 165.849 1.00 66.52  ? 481 THR A CB  1 
ATOM 112  O OG1 . THR A 1 465 ? 156.537 147.872 165.715 1.00 65.59  ? 481 THR A OG1 1 
ATOM 113  C CG2 . THR A 1 465 ? 154.941 148.705 167.316 1.00 64.53  ? 481 THR A CG2 1 
ATOM 114  N N   . VAL A 1 466 ? 151.920 148.388 165.670 1.00 54.36  ? 482 VAL A N   1 
ATOM 115  C CA  . VAL A 1 466 ? 150.629 149.065 165.740 1.00 58.71  ? 482 VAL A CA  1 
ATOM 116  C C   . VAL A 1 466 ? 150.450 149.596 167.159 1.00 59.46  ? 482 VAL A C   1 
ATOM 117  O O   . VAL A 1 466 ? 150.306 148.798 168.095 1.00 61.32  ? 482 VAL A O   1 
ATOM 118  C CB  . VAL A 1 466 ? 149.475 148.125 165.355 1.00 56.09  ? 482 VAL A CB  1 
ATOM 119  C CG1 . VAL A 1 466 ? 148.150 148.870 165.372 1.00 54.88  ? 482 VAL A CG1 1 
ATOM 120  C CG2 . VAL A 1 466 ? 149.725 147.509 163.989 1.00 55.82  ? 482 VAL A CG2 1 
ATOM 121  N N   . PRO A 1 467 ? 150.452 150.912 167.373 1.00 62.96  ? 483 PRO A N   1 
ATOM 122  C CA  . PRO A 1 467 ? 150.196 151.437 168.718 1.00 66.46  ? 483 PRO A CA  1 
ATOM 123  C C   . PRO A 1 467 ? 148.803 151.070 169.207 1.00 62.67  ? 483 PRO A C   1 
ATOM 124  O O   . PRO A 1 467 ? 147.864 150.886 168.429 1.00 68.71  ? 483 PRO A O   1 
ATOM 125  C CB  . PRO A 1 467 ? 150.342 152.954 168.545 1.00 69.56  ? 483 PRO A CB  1 
ATOM 126  C CG  . PRO A 1 467 ? 151.204 153.118 167.349 1.00 67.37  ? 483 PRO A CG  1 
ATOM 127  C CD  . PRO A 1 467 ? 150.861 151.976 166.440 1.00 64.66  ? 483 PRO A CD  1 
ATOM 128  N N   . MET A 1 468 ? 148.681 150.964 170.528 1.00 64.32  ? 484 MET A N   1 
ATOM 129  C CA  . MET A 1 468 ? 147.420 150.556 171.131 1.00 65.26  ? 484 MET A CA  1 
ATOM 130  C C   . MET A 1 468 ? 146.322 151.571 170.836 1.00 63.92  ? 484 MET A C   1 
ATOM 131  O O   . MET A 1 468 ? 146.525 152.784 170.940 1.00 67.17  ? 484 MET A O   1 
ATOM 132  C CB  . MET A 1 468 ? 147.589 150.396 172.643 1.00 67.79  ? 484 MET A CB  1 
ATOM 133  C CG  . MET A 1 468 ? 146.331 149.938 173.363 1.00 72.06  ? 484 MET A CG  1 
ATOM 134  S SD  . MET A 1 468 ? 146.564 149.747 175.141 1.00 81.64  ? 484 MET A SD  1 
ATOM 135  C CE  . MET A 1 468 ? 146.807 151.451 175.637 1.00 71.52  ? 484 MET A CE  1 
ATOM 136  N N   . ARG A 1 469 ? 145.149 151.059 170.465 1.00 64.18  ? 485 ARG A N   1 
ATOM 137  C CA  . ARG A 1 469 ? 143.941 151.863 170.284 1.00 63.41  ? 485 ARG A CA  1 
ATOM 138  C C   . ARG A 1 469 ? 144.158 153.035 169.330 1.00 66.08  ? 485 ARG A C   1 
ATOM 139  O O   . ARG A 1 469 ? 143.707 154.153 169.594 1.00 66.17  ? 485 ARG A O   1 
ATOM 140  C CB  . ARG A 1 469 ? 143.416 152.365 171.633 1.00 61.67  ? 485 ARG A CB  1 
ATOM 141  C CG  . ARG A 1 469 ? 142.854 151.263 172.515 1.00 65.36  ? 485 ARG A CG  1 
ATOM 142  C CD  . ARG A 1 469 ? 142.561 151.760 173.920 1.00 67.10  ? 485 ARG A CD  1 
ATOM 143  N NE  . ARG A 1 469 ? 142.045 150.697 174.775 1.00 70.20  ? 485 ARG A NE  1 
ATOM 144  C CZ  . ARG A 1 469 ? 141.771 150.837 176.065 1.00 69.92  ? 485 ARG A CZ  1 
ATOM 145  N NH1 . ARG A 1 469 ? 141.953 151.988 176.691 1.00 70.60  ? 485 ARG A NH1 1 
ATOM 146  N NH2 . ARG A 1 469 ? 141.302 149.795 176.745 1.00 69.06  ? 485 ARG A NH2 1 
ATOM 147  N N   . LYS A 1 470 ? 144.846 152.794 168.218 1.00 63.10  ? 486 LYS A N   1 
ATOM 148  C CA  . LYS A 1 470 ? 145.013 153.788 167.166 1.00 62.39  ? 486 LYS A CA  1 
ATOM 149  C C   . LYS A 1 470 ? 144.814 153.125 165.811 1.00 60.80  ? 486 LYS A C   1 
ATOM 150  O O   . LYS A 1 470 ? 145.368 152.051 165.554 1.00 60.59  ? 486 LYS A O   1 
ATOM 151  C CB  . LYS A 1 470 ? 146.394 154.444 167.231 1.00 62.48  ? 486 LYS A CB  1 
ATOM 152  C CG  . LYS A 1 470 ? 146.510 155.691 166.367 1.00 57.74  ? 486 LYS A CG  1 
ATOM 153  C CD  . LYS A 1 470 ? 147.943 156.182 166.262 1.00 60.76  ? 486 LYS A CD  1 
ATOM 154  C CE  . LYS A 1 470 ? 148.771 155.297 165.346 1.00 60.89  ? 486 LYS A CE  1 
ATOM 155  N NZ  . LYS A 1 470 ? 150.121 155.870 165.093 1.00 61.14  ? 486 LYS A NZ  1 
ATOM 156  N N   . TYR A 1 471 ? 144.026 153.765 164.952 1.00 57.64  ? 487 TYR A N   1 
ATOM 157  C CA  . TYR A 1 471 ? 143.843 153.280 163.592 1.00 50.12  ? 487 TYR A CA  1 
ATOM 158  C C   . TYR A 1 471 ? 145.059 153.635 162.747 1.00 52.76  ? 487 TYR A C   1 
ATOM 159  O O   . TYR A 1 471 ? 145.554 154.765 162.791 1.00 60.05  ? 487 TYR A O   1 
ATOM 160  C CB  . TYR A 1 471 ? 142.578 153.879 162.980 1.00 50.00  ? 487 TYR A CB  1 
ATOM 161  C CG  . TYR A 1 471 ? 141.317 153.560 163.752 1.00 54.60  ? 487 TYR A CG  1 
ATOM 162  C CD1 . TYR A 1 471 ? 140.628 152.375 163.536 1.00 56.00  ? 487 TYR A CD1 1 
ATOM 163  C CD2 . TYR A 1 471 ? 140.816 154.445 164.697 1.00 53.76  ? 487 TYR A CD2 1 
ATOM 164  C CE1 . TYR A 1 471 ? 139.476 152.079 164.239 1.00 55.68  ? 487 TYR A CE1 1 
ATOM 165  C CE2 . TYR A 1 471 ? 139.664 154.158 165.405 1.00 53.65  ? 487 TYR A CE2 1 
ATOM 166  C CZ  . TYR A 1 471 ? 138.999 152.974 165.172 1.00 57.31  ? 487 TYR A CZ  1 
ATOM 167  O OH  . TYR A 1 471 ? 137.852 152.684 165.874 1.00 56.94  ? 487 TYR A OH  1 
ATOM 168  N N   . MET A 1 472 ? 145.541 152.662 161.975 1.00 50.87  ? 488 MET A N   1 
ATOM 169  C CA  . MET A 1 472 ? 146.766 152.842 161.206 1.00 53.00  ? 488 MET A CA  1 
ATOM 170  C C   . MET A 1 472 ? 146.695 152.106 159.872 1.00 51.15  ? 488 MET A C   1 
ATOM 171  O O   . MET A 1 472 ? 146.615 150.871 159.851 1.00 58.67  ? 488 MET A O   1 
ATOM 172  C CB  . MET A 1 472 ? 147.970 152.344 162.009 1.00 48.75  ? 488 MET A CB  1 
ATOM 173  C CG  . MET A 1 472 ? 149.273 152.280 161.218 1.00 52.64  ? 488 MET A CG  1 
ATOM 174  S SD  . MET A 1 472 ? 150.674 151.729 162.209 1.00 60.81  ? 488 MET A SD  1 
ATOM 175  C CE  . MET A 1 472 ? 150.867 153.116 163.322 1.00 58.06  ? 488 MET A CE  1 
ATOM 176  N N   . PRO A 1 473 ? 146.720 152.816 158.744 1.00 44.31  ? 489 PRO A N   1 
ATOM 177  C CA  . PRO A 1 473 ? 146.917 152.135 157.456 1.00 39.74  ? 489 PRO A CA  1 
ATOM 178  C C   . PRO A 1 473 ? 148.248 151.399 157.437 1.00 43.89  ? 489 PRO A C   1 
ATOM 179  O O   . PRO A 1 473 ? 149.250 151.877 157.973 1.00 49.44  ? 489 PRO A O   1 
ATOM 180  C CB  . PRO A 1 473 ? 146.882 153.284 156.442 1.00 43.88  ? 489 PRO A CB  1 
ATOM 181  C CG  . PRO A 1 473 ? 146.076 154.341 157.099 1.00 46.14  ? 489 PRO A CG  1 
ATOM 182  C CD  . PRO A 1 473 ? 146.373 154.237 158.567 1.00 49.77  ? 489 PRO A CD  1 
ATOM 183  N N   . ILE A 1 474 ? 148.254 150.229 156.814 1.00 46.05  ? 490 ILE A N   1 
ATOM 184  C CA  . ILE A 1 474 ? 149.444 149.376 156.823 1.00 42.08  ? 490 ILE A CA  1 
ATOM 185  C C   . ILE A 1 474 ? 150.367 149.800 155.683 1.00 45.85  ? 490 ILE A C   1 
ATOM 186  O O   . ILE A 1 474 ? 149.943 149.781 154.516 1.00 52.97  ? 490 ILE A O   1 
ATOM 187  C CB  . ILE A 1 474 ? 149.050 147.908 156.693 1.00 35.52  ? 490 ILE A CB  1 
ATOM 188  C CG1 . ILE A 1 474 ? 148.099 147.507 157.825 1.00 39.85  ? 490 ILE A CG1 1 
ATOM 189  C CG2 . ILE A 1 474 ? 150.288 147.025 156.700 1.00 41.79  ? 490 ILE A CG2 1 
ATOM 190  C CD1 . ILE A 1 474 ? 148.676 147.685 159.218 1.00 48.35  ? 490 ILE A CD1 1 
ATOM 191  N N   . PRO A 1 475 ? 151.621 150.184 155.967 1.00 39.72  ? 491 PRO A N   1 
ATOM 192  C CA  . PRO A 1 475 ? 152.554 150.513 154.880 1.00 34.86  ? 491 PRO A CA  1 
ATOM 193  C C   . PRO A 1 475 ? 153.175 149.277 154.248 1.00 39.40  ? 491 PRO A C   1 
ATOM 194  O O   . PRO A 1 475 ? 154.283 148.872 154.613 1.00 46.28  ? 491 PRO A O   1 
ATOM 195  C CB  . PRO A 1 475 ? 153.610 151.375 155.581 1.00 42.32  ? 491 PRO A CB  1 
ATOM 196  C CG  . PRO A 1 475 ? 153.626 150.861 156.973 1.00 41.41  ? 491 PRO A CG  1 
ATOM 197  C CD  . PRO A 1 475 ? 152.209 150.459 157.291 1.00 43.71  ? 491 PRO A CD  1 
ATOM 198  N N   . TRP A 1 476 ? 152.464 148.669 153.302 1.00 35.55  ? 492 TRP A N   1 
ATOM 199  C CA  . TRP A 1 476 ? 152.957 147.463 152.651 1.00 28.85  ? 492 TRP A CA  1 
ATOM 200  C C   . TRP A 1 476 ? 154.260 147.750 151.913 1.00 31.60  ? 492 TRP A C   1 
ATOM 201  O O   . TRP A 1 476 ? 154.439 148.811 151.310 1.00 44.62  ? 492 TRP A O   1 
ATOM 202  C CB  . TRP A 1 476 ? 151.902 146.921 151.690 1.00 33.49  ? 492 TRP A CB  1 
ATOM 203  C CG  . TRP A 1 476 ? 150.574 146.720 152.354 1.00 28.92  ? 492 TRP A CG  1 
ATOM 204  C CD1 . TRP A 1 476 ? 149.526 147.594 152.369 1.00 29.62  ? 492 TRP A CD1 1 
ATOM 205  C CD2 . TRP A 1 476 ? 150.155 145.581 153.116 1.00 25.91  ? 492 TRP A CD2 1 
ATOM 206  N NE1 . TRP A 1 476 ? 148.481 147.069 153.087 1.00 27.55  ? 492 TRP A NE1 1 
ATOM 207  C CE2 . TRP A 1 476 ? 148.842 145.834 153.556 1.00 21.19  ? 492 TRP A CE2 1 
ATOM 208  C CE3 . TRP A 1 476 ? 150.762 144.372 153.465 1.00 32.62  ? 492 TRP A CE3 1 
ATOM 209  C CZ2 . TRP A 1 476 ? 148.125 144.924 154.327 1.00 26.10  ? 492 TRP A CZ2 1 
ATOM 210  C CZ3 . TRP A 1 476 ? 150.047 143.469 154.230 1.00 34.69  ? 492 TRP A CZ3 1 
ATOM 211  C CH2 . TRP A 1 476 ? 148.743 143.749 154.652 1.00 30.47  ? 492 TRP A CH2 1 
ATOM 212  N N   . SER A 1 477 ? 155.176 146.780 151.958 1.00 37.98  ? 493 SER A N   1 
ATOM 213  C CA  . SER A 1 477 ? 156.544 147.009 151.506 1.00 43.29  ? 493 SER A CA  1 
ATOM 214  C C   . SER A 1 477 ? 156.919 146.321 150.202 1.00 38.03  ? 493 SER A C   1 
ATOM 215  O O   . SER A 1 477 ? 157.713 146.893 149.449 1.00 37.56  ? 493 SER A O   1 
ATOM 216  C CB  . SER A 1 477 ? 157.531 146.560 152.592 1.00 46.27  ? 493 SER A CB  1 
ATOM 217  O OG  . SER A 1 477 ? 157.377 145.181 152.877 1.00 50.54  ? 493 SER A OG  1 
ATOM 218  N N   . LYS A 1 478 ? 156.396 145.134 149.899 1.00 31.49  ? 494 LYS A N   1 
ATOM 219  C CA  . LYS A 1 478 ? 156.785 144.419 148.692 1.00 29.11  ? 494 LYS A CA  1 
ATOM 220  C C   . LYS A 1 478 ? 155.545 143.862 148.010 1.00 22.51  ? 494 LYS A C   1 
ATOM 221  O O   . LYS A 1 478 ? 154.465 143.782 148.600 1.00 34.57  ? 494 LYS A O   1 
ATOM 222  C CB  . LYS A 1 478 ? 157.782 143.289 148.992 1.00 34.53  ? 494 LYS A CB  1 
ATOM 223  C CG  . LYS A 1 478 ? 157.183 142.051 149.638 1.00 21.78  ? 494 LYS A CG  1 
ATOM 224  C CD  . LYS A 1 478 ? 158.242 140.981 149.834 1.00 29.39  ? 494 LYS A CD  1 
ATOM 225  C CE  . LYS A 1 478 ? 157.630 139.652 150.235 1.00 33.71  ? 494 LYS A CE  1 
ATOM 226  N NZ  . LYS A 1 478 ? 158.654 138.577 150.331 1.00 40.32  ? 494 LYS A NZ  1 
ATOM 227  N N   . VAL A 1 479 ? 155.720 143.477 146.750 1.00 11.05  ? 495 VAL A N   1 
ATOM 228  C CA  . VAL A 1 479 ? 154.627 143.039 145.891 1.00 12.51  ? 495 VAL A CA  1 
ATOM 229  C C   . VAL A 1 479 ? 154.815 141.561 145.581 1.00 19.32  ? 495 VAL A C   1 
ATOM 230  O O   . VAL A 1 479 ? 155.876 141.150 145.095 1.00 22.89  ? 495 VAL A O   1 
ATOM 231  C CB  . VAL A 1 479 ? 154.574 143.864 144.596 1.00 13.86  ? 495 VAL A CB  1 
ATOM 232  C CG1 . VAL A 1 479 ? 153.454 143.369 143.694 1.00 22.45  ? 495 VAL A CG1 1 
ATOM 233  C CG2 . VAL A 1 479 ? 154.405 145.342 144.912 1.00 22.53  ? 495 VAL A CG2 1 
ATOM 234  N N   . THR A 1 480 ? 153.786 140.760 145.863 1.00 28.92  ? 496 THR A N   1 
ATOM 235  C CA  . THR A 1 480 ? 153.791 139.370 145.425 1.00 15.66  ? 496 THR A CA  1 
ATOM 236  C C   . THR A 1 480 ? 153.584 139.278 143.918 1.00 19.91  ? 496 THR A C   1 
ATOM 237  O O   . THR A 1 480 ? 154.276 138.517 143.233 1.00 16.87  ? 496 THR A O   1 
ATOM 238  C CB  . THR A 1 480 ? 152.710 138.581 146.164 1.00 20.88  ? 496 THR A CB  1 
ATOM 239  O OG1 . THR A 1 480 ? 152.929 138.670 147.578 1.00 35.39  ? 496 THR A OG1 1 
ATOM 240  C CG2 . THR A 1 480 ? 152.726 137.118 145.742 1.00 21.55  ? 496 THR A CG2 1 
ATOM 241  N N   . TYR A 1 481 ? 152.633 140.046 143.391 1.00 28.84  ? 497 TYR A N   1 
ATOM 242  C CA  . TYR A 1 481 ? 152.438 140.160 141.953 1.00 21.73  ? 497 TYR A CA  1 
ATOM 243  C C   . TYR A 1 481 ? 151.588 141.392 141.680 1.00 17.84  ? 497 TYR A C   1 
ATOM 244  O O   . TYR A 1 481 ? 150.772 141.802 142.510 1.00 27.83  ? 497 TYR A O   1 
ATOM 245  C CB  . TYR A 1 481 ? 151.787 138.902 141.364 1.00 24.98  ? 497 TYR A CB  1 
ATOM 246  C CG  . TYR A 1 481 ? 150.363 138.659 141.814 1.00 25.92  ? 497 TYR A CG  1 
ATOM 247  C CD1 . TYR A 1 481 ? 149.292 139.206 141.120 1.00 28.96  ? 497 TYR A CD1 1 
ATOM 248  C CD2 . TYR A 1 481 ? 150.089 137.873 142.925 1.00 22.70  ? 497 TYR A CD2 1 
ATOM 249  C CE1 . TYR A 1 481 ? 147.990 138.984 141.524 1.00 20.97  ? 497 TYR A CE1 1 
ATOM 250  C CE2 . TYR A 1 481 ? 148.789 137.645 143.335 1.00 18.97  ? 497 TYR A CE2 1 
ATOM 251  C CZ  . TYR A 1 481 ? 147.745 138.203 142.632 1.00 21.61  ? 497 TYR A CZ  1 
ATOM 252  O OH  . TYR A 1 481 ? 146.451 137.978 143.039 1.00 30.84  ? 497 TYR A OH  1 
ATOM 253  N N   . ASN A 1 482 ? 151.795 141.980 140.502 1.00 19.26  ? 498 ASN A N   1 
ATOM 254  C CA  . ASN A 1 482 ? 151.068 143.186 140.108 1.00 19.17  ? 498 ASN A CA  1 
ATOM 255  C C   . ASN A 1 482 ? 151.028 143.225 138.584 1.00 15.55  ? 498 ASN A C   1 
ATOM 256  O O   . ASN A 1 482 ? 152.071 143.382 137.943 1.00 32.35  ? 498 ASN A O   1 
ATOM 257  C CB  . ASN A 1 482 ? 151.730 144.431 140.681 1.00 10.41  ? 498 ASN A CB  1 
ATOM 258  C CG  . ASN A 1 482 ? 151.140 145.715 140.130 1.00 17.95  ? 498 ASN A CG  1 
ATOM 259  O OD1 . ASN A 1 482 ? 150.060 145.714 139.540 1.00 35.63  ? 498 ASN A OD1 1 
ATOM 260  N ND2 . ASN A 1 482 ? 151.849 146.820 140.323 1.00 30.85  ? 498 ASN A ND2 1 
ATOM 261  N N   . ASN A 1 483 ? 149.828 143.084 138.016 1.00 17.07  ? 499 ASN A N   1 
ATOM 262  C CA  . ASN A 1 483 ? 149.706 143.026 136.563 1.00 24.22  ? 499 ASN A CA  1 
ATOM 263  C C   . ASN A 1 483 ? 150.083 144.353 135.917 1.00 42.86  ? 499 ASN A C   1 
ATOM 264  O O   . ASN A 1 483 ? 150.904 144.386 134.993 1.00 53.72  ? 499 ASN A O   1 
ATOM 265  C CB  . ASN A 1 483 ? 148.282 142.628 136.175 1.00 29.24  ? 499 ASN A CB  1 
ATOM 266  C CG  . ASN A 1 483 ? 148.113 142.454 134.678 1.00 32.09  ? 499 ASN A CG  1 
ATOM 267  O OD1 . ASN A 1 483 ? 147.694 143.375 133.977 1.00 39.45  ? 499 ASN A OD1 1 
ATOM 268  N ND2 . ASN A 1 483 ? 148.439 141.267 134.179 1.00 33.68  ? 499 ASN A ND2 1 
ATOM 269  N N   . ALA A 1 484 ? 149.502 145.458 136.385 1.00 31.51  ? 500 ALA A N   1 
ATOM 270  C CA  . ALA A 1 484 ? 149.754 146.756 135.763 1.00 25.36  ? 500 ALA A CA  1 
ATOM 271  C C   . ALA A 1 484 ? 149.479 147.867 136.765 1.00 25.09  ? 500 ALA A C   1 
ATOM 272  O O   . ALA A 1 484 ? 148.317 148.212 137.000 1.00 36.67  ? 500 ALA A O   1 
ATOM 273  C CB  . ALA A 1 484 ? 148.889 146.932 134.517 1.00 33.63  ? 500 ALA A CB  1 
ATOM 274  N N   . GLU A 1 485 ? 150.542 148.421 137.347 1.00 27.34  ? 501 GLU A N   1 
ATOM 275  C CA  . GLU A 1 485 ? 150.499 149.674 138.100 1.00 34.04  ? 501 GLU A CA  1 
ATOM 276  C C   . GLU A 1 485 ? 149.402 149.698 139.160 1.00 32.69  ? 501 GLU A C   1 
ATOM 277  O O   . GLU A 1 485 ? 148.711 150.710 139.316 1.00 41.93  ? 501 GLU A O   1 
ATOM 278  C CB  . GLU A 1 485 ? 150.333 150.869 137.155 1.00 41.88  ? 501 GLU A CB  1 
ATOM 279  C CG  . GLU A 1 485 ? 151.444 150.995 136.125 1.00 33.11  ? 501 GLU A CG  1 
ATOM 280  C CD  . GLU A 1 485 ? 151.228 152.150 135.166 1.00 45.95  ? 501 GLU A CD  1 
ATOM 281  O OE1 . GLU A 1 485 ? 150.188 152.833 135.279 1.00 47.31  ? 501 GLU A OE1 1 
ATOM 282  O OE2 . GLU A 1 485 ? 152.099 152.375 134.300 1.00 48.83  ? 501 GLU A OE2 1 
ATOM 283  N N   . PHE A 1 486 ? 149.223 148.606 139.904 1.00 16.08  ? 502 PHE A N   1 
ATOM 284  C CA  . PHE A 1 486 ? 148.269 148.608 141.007 1.00 24.16  ? 502 PHE A CA  1 
ATOM 285  C C   . PHE A 1 486 ? 148.868 149.133 142.305 1.00 27.55  ? 502 PHE A C   1 
ATOM 286  O O   . PHE A 1 486 ? 148.126 149.306 143.278 1.00 37.20  ? 502 PHE A O   1 
ATOM 287  C CB  . PHE A 1 486 ? 147.721 147.199 141.238 1.00 27.36  ? 502 PHE A CB  1 
ATOM 288  C CG  . PHE A 1 486 ? 146.605 146.823 140.307 1.00 20.62  ? 502 PHE A CG  1 
ATOM 289  C CD1 . PHE A 1 486 ? 145.287 147.078 140.646 1.00 22.61  ? 502 PHE A CD1 1 
ATOM 290  C CD2 . PHE A 1 486 ? 146.873 146.214 139.095 1.00 20.52  ? 502 PHE A CD2 1 
ATOM 291  C CE1 . PHE A 1 486 ? 144.259 146.734 139.791 1.00 22.42  ? 502 PHE A CE1 1 
ATOM 292  C CE2 . PHE A 1 486 ? 145.849 145.867 138.237 1.00 22.55  ? 502 PHE A CE2 1 
ATOM 293  C CZ  . PHE A 1 486 ? 144.540 146.127 138.586 1.00 18.82  ? 502 PHE A CZ  1 
ATOM 294  N N   . TRP A 1 487 ? 150.173 149.391 142.347 1.00 23.74  ? 503 TRP A N   1 
ATOM 295  C CA  . TRP A 1 487 ? 150.828 149.810 143.576 1.00 20.31  ? 503 TRP A CA  1 
ATOM 296  C C   . TRP A 1 487 ? 151.941 150.791 143.238 1.00 37.69  ? 503 TRP A C   1 
ATOM 297  O O   . TRP A 1 487 ? 152.495 150.777 142.136 1.00 43.19  ? 503 TRP A O   1 
ATOM 298  C CB  . TRP A 1 487 ? 151.379 148.602 144.343 1.00 24.75  ? 503 TRP A CB  1 
ATOM 299  C CG  . TRP A 1 487 ? 151.926 148.928 145.694 1.00 25.18  ? 503 TRP A CG  1 
ATOM 300  C CD1 . TRP A 1 487 ? 151.218 149.321 146.791 1.00 28.55  ? 503 TRP A CD1 1 
ATOM 301  C CD2 . TRP A 1 487 ? 153.298 148.875 146.100 1.00 29.53  ? 503 TRP A CD2 1 
ATOM 302  N NE1 . TRP A 1 487 ? 152.064 149.521 147.853 1.00 28.07  ? 503 TRP A NE1 1 
ATOM 303  C CE2 . TRP A 1 487 ? 153.347 149.254 147.455 1.00 31.27  ? 503 TRP A CE2 1 
ATOM 304  C CE3 . TRP A 1 487 ? 154.490 148.546 145.448 1.00 30.78  ? 503 TRP A CE3 1 
ATOM 305  C CZ2 . TRP A 1 487 ? 154.539 149.314 148.170 1.00 39.76  ? 503 TRP A CZ2 1 
ATOM 306  C CZ3 . TRP A 1 487 ? 155.673 148.606 146.159 1.00 38.85  ? 503 TRP A CZ3 1 
ATOM 307  C CH2 . TRP A 1 487 ? 155.689 148.987 147.506 1.00 42.86  ? 503 TRP A CH2 1 
ATOM 308  N N   . ASP A 1 488 ? 152.261 151.648 144.206 1.00 52.39  ? 504 ASP A N   1 
ATOM 309  C CA  . ASP A 1 488 ? 153.296 152.662 144.030 1.00 51.89  ? 504 ASP A CA  1 
ATOM 310  C C   . ASP A 1 488 ? 154.206 152.640 145.248 1.00 54.30  ? 504 ASP A C   1 
ATOM 311  O O   . ASP A 1 488 ? 153.722 152.581 146.383 1.00 47.90  ? 504 ASP A O   1 
ATOM 312  C CB  . ASP A 1 488 ? 152.680 154.049 143.840 1.00 46.76  ? 504 ASP A CB  1 
ATOM 313  C CG  . ASP A 1 488 ? 153.712 155.102 143.489 1.00 56.38  ? 504 ASP A CG  1 
ATOM 314  O OD1 . ASP A 1 488 ? 154.906 154.754 143.376 1.00 54.75  ? 504 ASP A OD1 1 
ATOM 315  O OD2 . ASP A 1 488 ? 153.330 156.280 143.325 1.00 60.92  ? 504 ASP A OD2 1 
ATOM 316  N N   . SER A 1 489 ? 155.518 152.690 145.011 1.00 55.96  ? 505 SER A N   1 
ATOM 317  C CA  . SER A 1 489 ? 156.476 152.639 146.110 1.00 52.90  ? 505 SER A CA  1 
ATOM 318  C C   . SER A 1 489 ? 156.351 153.839 147.039 1.00 58.13  ? 505 SER A C   1 
ATOM 319  O O   . SER A 1 489 ? 156.410 153.674 148.262 1.00 58.68  ? 505 SER A O   1 
ATOM 320  C CB  . SER A 1 489 ? 157.898 152.554 145.558 1.00 55.44  ? 505 SER A CB  1 
ATOM 321  O OG  . SER A 1 489 ? 158.067 151.392 144.766 1.00 57.90  ? 505 SER A OG  1 
ATOM 322  N N   . ASN A 1 490 ? 156.186 155.042 146.490 1.00 57.09  ? 506 ASN A N   1 
ATOM 323  C CA  . ASN A 1 490 ? 156.068 156.246 147.302 1.00 54.56  ? 506 ASN A CA  1 
ATOM 324  C C   . ASN A 1 490 ? 154.737 156.343 148.036 1.00 58.56  ? 506 ASN A C   1 
ATOM 325  O O   . ASN A 1 490 ? 154.594 157.199 148.916 1.00 55.43  ? 506 ASN A O   1 
ATOM 326  C CB  . ASN A 1 490 ? 156.265 157.494 146.433 1.00 57.19  ? 506 ASN A CB  1 
ATOM 327  C CG  . ASN A 1 490 ? 155.347 157.519 145.226 1.00 65.06  ? 506 ASN A CG  1 
ATOM 328  O OD1 . ASN A 1 490 ? 154.181 157.899 145.326 1.00 67.18  ? 506 ASN A OD1 1 
ATOM 329  N ND2 . ASN A 1 490 ? 155.875 157.120 144.074 1.00 62.09  ? 506 ASN A ND2 1 
ATOM 330  N N   . ASN A 1 491 ? 153.767 155.494 147.701 1.00 58.98  ? 507 ASN A N   1 
ATOM 331  C CA  . ASN A 1 491 ? 152.484 155.429 148.401 1.00 54.80  ? 507 ASN A CA  1 
ATOM 332  C C   . ASN A 1 491 ? 152.194 153.980 148.776 1.00 49.85  ? 507 ASN A C   1 
ATOM 333  O O   . ASN A 1 491 ? 151.261 153.360 148.256 1.00 48.90  ? 507 ASN A O   1 
ATOM 334  C CB  . ASN A 1 491 ? 151.365 156.009 147.539 1.00 53.32  ? 507 ASN A CB  1 
ATOM 335  C CG  . ASN A 1 491 ? 151.494 157.506 147.350 1.00 54.34  ? 507 ASN A CG  1 
ATOM 336  O OD1 . ASN A 1 491 ? 150.950 158.289 148.128 1.00 51.67  ? 507 ASN A OD1 1 
ATOM 337  N ND2 . ASN A 1 491 ? 152.219 157.912 146.316 1.00 58.62  ? 507 ASN A ND2 1 
ATOM 338  N N   . PRO A 1 492 ? 152.986 153.408 149.687 1.00 44.49  ? 508 PRO A N   1 
ATOM 339  C CA  . PRO A 1 492 ? 152.828 151.980 150.003 1.00 44.31  ? 508 PRO A CA  1 
ATOM 340  C C   . PRO A 1 492 ? 151.468 151.616 150.570 1.00 46.79  ? 508 PRO A C   1 
ATOM 341  O O   . PRO A 1 492 ? 151.001 150.494 150.336 1.00 47.26  ? 508 PRO A O   1 
ATOM 342  C CB  . PRO A 1 492 ? 153.942 151.722 151.027 1.00 44.26  ? 508 PRO A CB  1 
ATOM 343  C CG  . PRO A 1 492 ? 154.225 153.056 151.628 1.00 44.46  ? 508 PRO A CG  1 
ATOM 344  C CD  . PRO A 1 492 ? 153.998 154.058 150.537 1.00 44.59  ? 508 PRO A CD  1 
ATOM 345  N N   . THR A 1 493 ? 150.818 152.519 151.305 1.00 47.86  ? 509 THR A N   1 
ATOM 346  C CA  . THR A 1 493 ? 149.577 152.177 151.990 1.00 39.37  ? 509 THR A CA  1 
ATOM 347  C C   . THR A 1 493 ? 148.392 152.045 151.044 1.00 36.41  ? 509 THR A C   1 
ATOM 348  O O   . THR A 1 493 ? 147.326 151.591 151.475 1.00 44.64  ? 509 THR A O   1 
ATOM 349  C CB  . THR A 1 493 ? 149.257 153.232 153.051 1.00 39.35  ? 509 THR A CB  1 
ATOM 350  O OG1 . THR A 1 493 ? 149.111 154.514 152.426 1.00 49.68  ? 509 THR A OG1 1 
ATOM 351  C CG2 . THR A 1 493 ? 150.360 153.302 154.093 1.00 40.55  ? 509 THR A CG2 1 
ATOM 352  N N   . ARG A 1 494 ? 148.544 152.421 149.778 1.00 35.22  ? 510 ARG A N   1 
ATOM 353  C CA  . ARG A 1 494 ? 147.426 152.532 148.851 1.00 34.62  ? 510 ARG A CA  1 
ATOM 354  C C   . ARG A 1 494 ? 147.559 151.518 147.724 1.00 38.71  ? 510 ARG A C   1 
ATOM 355  O O   . ARG A 1 494 ? 148.628 151.389 147.120 1.00 42.36  ? 510 ARG A O   1 
ATOM 356  C CB  . ARG A 1 494 ? 147.350 153.942 148.263 1.00 34.25  ? 510 ARG A CB  1 
ATOM 357  C CG  . ARG A 1 494 ? 147.152 155.037 149.290 1.00 37.80  ? 510 ARG A CG  1 
ATOM 358  C CD  . ARG A 1 494 ? 147.083 156.397 148.622 1.00 38.49  ? 510 ARG A CD  1 
ATOM 359  N NE  . ARG A 1 494 ? 146.932 157.481 149.585 1.00 36.83  ? 510 ARG A NE  1 
ATOM 360  C CZ  . ARG A 1 494 ? 146.846 158.764 149.259 1.00 47.17  ? 510 ARG A CZ  1 
ATOM 361  N NH1 . ARG A 1 494 ? 146.891 159.163 147.999 1.00 50.88  ? 510 ARG A NH1 1 
ATOM 362  N NH2 . ARG A 1 494 ? 146.711 159.670 150.223 1.00 46.75  ? 510 ARG A NH2 1 
ATOM 363  N N   . LEU A 1 495 ? 146.470 150.803 147.450 1.00 27.33  ? 511 LEU A N   1 
ATOM 364  C CA  . LEU A 1 495 ? 146.335 150.062 146.204 1.00 17.70  ? 511 LEU A CA  1 
ATOM 365  C C   . LEU A 1 495 ? 145.522 150.894 145.223 1.00 18.82  ? 511 LEU A C   1 
ATOM 366  O O   . LEU A 1 495 ? 144.357 151.211 145.480 1.00 20.24  ? 511 LEU A O   1 
ATOM 367  C CB  . LEU A 1 495 ? 145.654 148.714 146.445 1.00 21.44  ? 511 LEU A CB  1 
ATOM 368  C CG  . LEU A 1 495 ? 146.513 147.595 147.035 1.00 20.09  ? 511 LEU A CG  1 
ATOM 369  C CD1 . LEU A 1 495 ? 145.661 146.376 147.344 1.00 22.09  ? 511 LEU A CD1 1 
ATOM 370  C CD2 . LEU A 1 495 ? 147.638 147.225 146.085 1.00 26.80  ? 511 LEU A CD2 1 
ATOM 371  N N   . VAL A 1 496 ? 146.131 151.238 144.092 1.00 32.18  ? 512 VAL A N   1 
ATOM 372  C CA  . VAL A 1 496 ? 145.572 152.206 143.157 1.00 33.61  ? 512 VAL A CA  1 
ATOM 373  C C   . VAL A 1 496 ? 144.946 151.466 141.984 1.00 27.66  ? 512 VAL A C   1 
ATOM 374  O O   . VAL A 1 496 ? 145.514 150.496 141.473 1.00 42.03  ? 512 VAL A O   1 
ATOM 375  C CB  . VAL A 1 496 ? 146.645 153.198 142.663 1.00 36.30  ? 512 VAL A CB  1 
ATOM 376  C CG1 . VAL A 1 496 ? 146.020 154.249 141.763 1.00 43.96  ? 512 VAL A CG1 1 
ATOM 377  C CG2 . VAL A 1 496 ? 147.348 153.849 143.841 1.00 26.65  ? 512 VAL A CG2 1 
ATOM 378  N N   . VAL A 1 497 ? 143.774 151.934 141.563 1.00 23.97  ? 513 VAL A N   1 
ATOM 379  C CA  . VAL A 1 497 ? 143.049 151.342 140.439 1.00 29.49  ? 513 VAL A CA  1 
ATOM 380  C C   . VAL A 1 497 ? 143.535 152.027 139.163 1.00 33.33  ? 513 VAL A C   1 
ATOM 381  O O   . VAL A 1 497 ? 143.401 153.256 139.046 1.00 46.13  ? 513 VAL A O   1 
ATOM 382  C CB  . VAL A 1 497 ? 141.533 151.503 140.606 1.00 36.64  ? 513 VAL A CB  1 
ATOM 383  C CG1 . VAL A 1 497 ? 140.800 150.928 139.402 1.00 37.37  ? 513 VAL A CG1 1 
ATOM 384  C CG2 . VAL A 1 497 ? 141.068 150.839 141.891 1.00 41.14  ? 513 VAL A CG2 1 
ATOM 385  N N   . PRO A 1 498 ? 144.095 151.290 138.194 1.00 34.92  ? 514 PRO A N   1 
ATOM 386  C CA  . PRO A 1 498 ? 144.499 151.931 136.934 1.00 37.06  ? 514 PRO A CA  1 
ATOM 387  C C   . PRO A 1 498 ? 143.313 152.416 136.113 1.00 41.06  ? 514 PRO A C   1 
ATOM 388  O O   . PRO A 1 498 ? 142.160 152.318 136.545 1.00 46.89  ? 514 PRO A O   1 
ATOM 389  C CB  . PRO A 1 498 ? 145.275 150.824 136.206 1.00 35.83  ? 514 PRO A CB  1 
ATOM 390  C CG  . PRO A 1 498 ? 144.820 149.553 136.829 1.00 32.67  ? 514 PRO A CG  1 
ATOM 391  C CD  . PRO A 1 498 ? 144.527 149.884 138.256 1.00 34.16  ? 514 PRO A CD  1 
ATOM 392  N N   . LYS A 1 499 ? 143.596 152.943 134.921 1.00 43.97  ? 515 LYS A N   1 
ATOM 393  C CA  . LYS A 1 499 ? 142.566 153.598 134.119 1.00 49.89  ? 515 LYS A CA  1 
ATOM 394  C C   . LYS A 1 499 ? 141.514 152.606 133.634 1.00 51.14  ? 515 LYS A C   1 
ATOM 395  O O   . LYS A 1 499 ? 140.309 152.834 133.789 1.00 50.14  ? 515 LYS A O   1 
ATOM 396  C CB  . LYS A 1 499 ? 143.221 154.313 132.935 1.00 47.03  ? 515 LYS A CB  1 
ATOM 397  C CG  . LYS A 1 499 ? 142.254 155.049 132.024 1.00 53.18  ? 515 LYS A CG  1 
ATOM 398  C CD  . LYS A 1 499 ? 143.000 155.817 130.945 1.00 53.89  ? 515 LYS A CD  1 
ATOM 399  C CE  . LYS A 1 499 ? 142.047 156.598 130.058 1.00 53.45  ? 515 LYS A CE  1 
ATOM 400  N NZ  . LYS A 1 499 ? 142.768 157.381 129.017 1.00 52.70  ? 515 LYS A NZ  1 
ATOM 401  N N   . GLY A 1 500 ? 141.951 151.498 133.040 1.00 43.05  ? 516 GLY A N   1 
ATOM 402  C CA  . GLY A 1 500 ? 141.043 150.602 132.349 1.00 42.17  ? 516 GLY A CA  1 
ATOM 403  C C   . GLY A 1 500 ? 140.307 149.608 133.222 1.00 42.98  ? 516 GLY A C   1 
ATOM 404  O O   . GLY A 1 500 ? 140.264 148.419 132.893 1.00 45.66  ? 516 GLY A O   1 
ATOM 405  N N   . ILE A 1 501 ? 139.720 150.061 134.327 1.00 36.06  ? 517 ILE A N   1 
ATOM 406  C CA  . ILE A 1 501 ? 138.976 149.197 135.236 1.00 31.64  ? 517 ILE A CA  1 
ATOM 407  C C   . ILE A 1 501 ? 137.708 149.913 135.680 1.00 27.68  ? 517 ILE A C   1 
ATOM 408  O O   . ILE A 1 501 ? 137.715 151.129 135.903 1.00 38.16  ? 517 ILE A O   1 
ATOM 409  C CB  . ILE A 1 501 ? 139.828 148.787 136.454 1.00 28.84  ? 517 ILE A CB  1 
ATOM 410  C CG1 . ILE A 1 501 ? 141.021 147.945 135.993 1.00 30.14  ? 517 ILE A CG1 1 
ATOM 411  C CG2 . ILE A 1 501 ? 138.976 148.023 137.457 1.00 38.11  ? 517 ILE A CG2 1 
ATOM 412  C CD1 . ILE A 1 501 ? 141.985 147.582 137.094 1.00 31.84  ? 517 ILE A CD1 1 
ATOM 413  N N   . THR A 1 502 ? 136.621 149.152 135.808 1.00 26.58  ? 518 THR A N   1 
ATOM 414  C CA  . THR A 1 502 ? 135.339 149.673 136.262 1.00 28.33  ? 518 THR A CA  1 
ATOM 415  C C   . THR A 1 502 ? 134.887 149.096 137.595 1.00 32.69  ? 518 THR A C   1 
ATOM 416  O O   . THR A 1 502 ? 134.379 149.842 138.434 1.00 31.34  ? 518 THR A O   1 
ATOM 417  C CB  . THR A 1 502 ? 134.253 149.396 135.214 1.00 31.42  ? 518 THR A CB  1 
ATOM 418  O OG1 . THR A 1 502 ? 134.662 149.918 133.944 1.00 32.39  ? 518 THR A OG1 1 
ATOM 419  C CG2 . THR A 1 502 ? 132.937 150.040 135.623 1.00 33.89  ? 518 THR A CG2 1 
ATOM 420  N N   . LYS A 1 503 ? 135.053 147.792 137.810 1.00 34.40  ? 519 LYS A N   1 
ATOM 421  C CA  . LYS A 1 503 ? 134.690 147.152 139.065 1.00 26.44  ? 519 LYS A CA  1 
ATOM 422  C C   . LYS A 1 503 ? 135.853 146.295 139.541 1.00 28.84  ? 519 LYS A C   1 
ATOM 423  O O   . LYS A 1 503 ? 136.580 145.708 138.736 1.00 30.25  ? 519 LYS A O   1 
ATOM 424  C CB  . LYS A 1 503 ? 133.431 146.285 138.924 1.00 24.71  ? 519 LYS A CB  1 
ATOM 425  C CG  . LYS A 1 503 ? 132.177 147.056 138.544 1.00 29.02  ? 519 LYS A CG  1 
ATOM 426  C CD  . LYS A 1 503 ? 130.939 146.177 138.640 1.00 21.91  ? 519 LYS A CD  1 
ATOM 427  C CE  . LYS A 1 503 ? 129.674 146.948 138.307 1.00 34.76  ? 519 LYS A CE  1 
ATOM 428  N NZ  . LYS A 1 503 ? 128.452 146.117 138.497 1.00 40.56  ? 519 LYS A NZ  1 
ATOM 429  N N   . VAL A 1 504 ? 136.022 146.227 140.862 1.00 23.52  ? 520 VAL A N   1 
ATOM 430  C CA  . VAL A 1 504 ? 137.128 145.505 141.471 1.00 23.58  ? 520 VAL A CA  1 
ATOM 431  C C   . VAL A 1 504 ? 136.629 144.740 142.689 1.00 15.48  ? 520 VAL A C   1 
ATOM 432  O O   . VAL A 1 504 ? 135.560 145.015 143.236 1.00 39.59  ? 520 VAL A O   1 
ATOM 433  C CB  . VAL A 1 504 ? 138.285 146.444 141.876 1.00 32.27  ? 520 VAL A CB  1 
ATOM 434  C CG1 . VAL A 1 504 ? 138.870 147.120 140.651 1.00 39.13  ? 520 VAL A CG1 1 
ATOM 435  C CG2 . VAL A 1 504 ? 137.810 147.476 142.890 1.00 30.99  ? 520 VAL A CG2 1 
ATOM 436  N N   . ARG A 1 505 ? 137.432 143.765 143.105 1.00 22.71  ? 521 ARG A N   1 
ATOM 437  C CA  . ARG A 1 505 ? 137.220 143.020 144.337 1.00 19.89  ? 521 ARG A CA  1 
ATOM 438  C C   . ARG A 1 505 ? 138.492 143.088 145.169 1.00 25.84  ? 521 ARG A C   1 
ATOM 439  O O   . ARG A 1 505 ? 139.592 142.863 144.654 1.00 31.44  ? 521 ARG A O   1 
ATOM 440  C CB  . ARG A 1 505 ? 136.857 141.560 144.052 1.00 21.93  ? 521 ARG A CB  1 
ATOM 441  C CG  . ARG A 1 505 ? 136.306 140.812 145.252 1.00 22.49  ? 521 ARG A CG  1 
ATOM 442  C CD  . ARG A 1 505 ? 136.433 139.309 145.077 1.00 27.37  ? 521 ARG A CD  1 
ATOM 443  N NE  . ARG A 1 505 ? 135.910 138.855 143.794 1.00 27.90  ? 521 ARG A NE  1 
ATOM 444  C CZ  . ARG A 1 505 ? 134.645 138.529 143.565 1.00 34.29  ? 521 ARG A CZ  1 
ATOM 445  N NH1 . ARG A 1 505 ? 133.726 138.606 144.514 1.00 37.41  ? 521 ARG A NH1 1 
ATOM 446  N NH2 . ARG A 1 505 ? 134.292 138.114 142.352 1.00 28.28  ? 521 ARG A NH2 1 
ATOM 447  N N   . VAL A 1 506 ? 138.342 143.399 146.454 1.00 23.11  ? 522 VAL A N   1 
ATOM 448  C CA  . VAL A 1 506 ? 139.472 143.606 147.350 1.00 15.82  ? 522 VAL A CA  1 
ATOM 449  C C   . VAL A 1 506 ? 139.332 142.677 148.547 1.00 11.13  ? 522 VAL A C   1 
ATOM 450  O O   . VAL A 1 506 ? 138.232 142.496 149.081 1.00 29.58  ? 522 VAL A O   1 
ATOM 451  C CB  . VAL A 1 506 ? 139.574 145.080 147.803 1.00 9.00   ? 522 VAL A CB  1 
ATOM 452  C CG1 . VAL A 1 506 ? 138.346 145.495 148.603 1.00 25.48  ? 522 VAL A CG1 1 
ATOM 453  C CG2 . VAL A 1 506 ? 140.840 145.301 148.606 1.00 22.41  ? 522 VAL A CG2 1 
ATOM 454  N N   . ALA A 1 507 ? 140.450 142.085 148.962 1.00 14.45  ? 523 ALA A N   1 
ATOM 455  C CA  . ALA A 1 507 ? 140.466 141.163 150.088 1.00 18.19  ? 523 ALA A CA  1 
ATOM 456  C C   . ALA A 1 507 ? 141.846 141.190 150.727 1.00 19.75  ? 523 ALA A C   1 
ATOM 457  O O   . ALA A 1 507 ? 142.815 141.676 150.138 1.00 36.35  ? 523 ALA A O   1 
ATOM 458  C CB  . ALA A 1 507 ? 140.106 139.738 149.655 1.00 15.45  ? 523 ALA A CB  1 
ATOM 459  N N   . GLY A 1 508 ? 141.926 140.659 151.943 1.00 7.53   ? 524 GLY A N   1 
ATOM 460  C CA  . GLY A 1 508 ? 143.188 140.636 152.660 1.00 20.29  ? 524 GLY A CA  1 
ATOM 461  C C   . GLY A 1 508 ? 143.114 139.717 153.858 1.00 22.32  ? 524 GLY A C   1 
ATOM 462  O O   . GLY A 1 508 ? 142.053 139.192 154.207 1.00 32.71  ? 524 GLY A O   1 
ATOM 463  N N   . ASN A 1 509 ? 144.274 139.530 154.485 1.00 24.50  ? 525 ASN A N   1 
ATOM 464  C CA  . ASN A 1 509 ? 144.393 138.689 155.666 1.00 26.47  ? 525 ASN A CA  1 
ATOM 465  C C   . ASN A 1 509 ? 145.453 139.288 156.579 1.00 20.89  ? 525 ASN A C   1 
ATOM 466  O O   . ASN A 1 509 ? 146.326 140.038 156.135 1.00 29.69  ? 525 ASN A O   1 
ATOM 467  C CB  . ASN A 1 509 ? 144.746 137.245 155.288 1.00 21.00  ? 525 ASN A CB  1 
ATOM 468  C CG  . ASN A 1 509 ? 144.747 136.310 156.481 1.00 23.68  ? 525 ASN A CG  1 
ATOM 469  O OD1 . ASN A 1 509 ? 144.483 136.722 157.610 1.00 37.29  ? 525 ASN A OD1 1 
ATOM 470  N ND2 . ASN A 1 509 ? 145.035 135.038 156.234 1.00 33.66  ? 525 ASN A ND2 1 
ATOM 471  N N   . VAL A 1 510 ? 145.367 138.951 157.864 1.00 28.75  ? 526 VAL A N   1 
ATOM 472  C CA  . VAL A 1 510 ? 146.226 139.536 158.887 1.00 27.40  ? 526 VAL A CA  1 
ATOM 473  C C   . VAL A 1 510 ? 146.719 138.441 159.821 1.00 38.96  ? 526 VAL A C   1 
ATOM 474  O O   . VAL A 1 510 ? 146.046 137.424 160.020 1.00 43.41  ? 526 VAL A O   1 
ATOM 475  C CB  . VAL A 1 510 ? 145.487 140.631 159.686 1.00 33.26  ? 526 VAL A CB  1 
ATOM 476  C CG1 . VAL A 1 510 ? 146.398 141.218 160.753 1.00 33.02  ? 526 VAL A CG1 1 
ATOM 477  C CG2 . VAL A 1 510 ? 144.978 141.715 158.752 1.00 39.26  ? 526 VAL A CG2 1 
ATOM 478  N N   . LEU A 1 511 ? 147.902 138.655 160.393 1.00 39.55  ? 527 LEU A N   1 
ATOM 479  C CA  . LEU A 1 511 ? 148.472 137.775 161.404 1.00 41.09  ? 527 LEU A CA  1 
ATOM 480  C C   . LEU A 1 511 ? 149.175 138.623 162.452 1.00 41.71  ? 527 LEU A C   1 
ATOM 481  O O   . LEU A 1 511 ? 150.108 139.366 162.129 1.00 45.72  ? 527 LEU A O   1 
ATOM 482  C CB  . LEU A 1 511 ? 149.454 136.777 160.782 1.00 41.32  ? 527 LEU A CB  1 
ATOM 483  C CG  . LEU A 1 511 ? 150.084 135.770 161.746 1.00 43.87  ? 527 LEU A CG  1 
ATOM 484  C CD1 . LEU A 1 511 ? 149.036 134.816 162.292 1.00 42.94  ? 527 LEU A CD1 1 
ATOM 485  C CD2 . LEU A 1 511 ? 151.200 135.005 161.058 1.00 46.36  ? 527 LEU A CD2 1 
ATOM 486  N N   . TRP A 1 512 ? 148.731 138.510 163.700 1.00 46.60  ? 528 TRP A N   1 
ATOM 487  C CA  . TRP A 1 512 ? 149.305 139.261 164.805 1.00 49.25  ? 528 TRP A CA  1 
ATOM 488  C C   . TRP A 1 512 ? 150.222 138.372 165.639 1.00 52.41  ? 528 TRP A C   1 
ATOM 489  O O   . TRP A 1 512 ? 150.261 137.149 165.485 1.00 53.80  ? 528 TRP A O   1 
ATOM 490  C CB  . TRP A 1 512 ? 148.202 139.846 165.691 1.00 46.50  ? 528 TRP A CB  1 
ATOM 491  C CG  . TRP A 1 512 ? 147.212 140.694 164.959 1.00 43.77  ? 528 TRP A CG  1 
ATOM 492  C CD1 . TRP A 1 512 ? 146.102 140.266 164.292 1.00 49.40  ? 528 TRP A CD1 1 
ATOM 493  C CD2 . TRP A 1 512 ? 147.235 142.119 164.829 1.00 47.67  ? 528 TRP A CD2 1 
ATOM 494  N NE1 . TRP A 1 512 ? 145.434 141.337 163.751 1.00 46.25  ? 528 TRP A NE1 1 
ATOM 495  C CE2 . TRP A 1 512 ? 146.109 142.486 164.066 1.00 45.26  ? 528 TRP A CE2 1 
ATOM 496  C CE3 . TRP A 1 512 ? 148.099 143.121 165.281 1.00 51.27  ? 528 TRP A CE3 1 
ATOM 497  C CZ2 . TRP A 1 512 ? 145.825 143.811 163.746 1.00 47.98  ? 528 TRP A CZ2 1 
ATOM 498  C CZ3 . TRP A 1 512 ? 147.815 144.435 164.962 1.00 48.86  ? 528 TRP A CZ3 1 
ATOM 499  C CH2 . TRP A 1 512 ? 146.688 144.768 164.201 1.00 49.12  ? 528 TRP A CH2 1 
ATOM 500  N N   . ASP A 1 513 ? 150.972 139.009 166.533 1.00 55.56  ? 529 ASP A N   1 
ATOM 501  C CA  . ASP A 1 513 ? 151.792 138.271 167.481 1.00 54.27  ? 529 ASP A CA  1 
ATOM 502  C C   . ASP A 1 513 ? 150.913 137.629 168.550 1.00 53.19  ? 529 ASP A C   1 
ATOM 503  O O   . ASP A 1 513 ? 149.785 138.061 168.800 1.00 51.29  ? 529 ASP A O   1 
ATOM 504  C CB  . ASP A 1 513 ? 152.824 139.194 168.128 1.00 57.43  ? 529 ASP A CB  1 
ATOM 505  C CG  . ASP A 1 513 ? 152.188 140.357 168.860 1.00 59.28  ? 529 ASP A CG  1 
ATOM 506  O OD1 . ASP A 1 513 ? 151.099 140.800 168.439 1.00 62.30  ? 529 ASP A OD1 1 
ATOM 507  O OD2 . ASP A 1 513 ? 152.776 140.829 169.855 1.00 58.52  ? 529 ASP A OD2 1 
ATOM 508  N N   . SER A 1 514 ? 151.442 136.584 169.180 1.00 59.02  ? 530 SER A N   1 
ATOM 509  C CA  . SER A 1 514 ? 150.677 135.828 170.165 1.00 60.02  ? 530 SER A CA  1 
ATOM 510  C C   . SER A 1 514 ? 150.291 136.726 171.335 1.00 56.51  ? 530 SER A C   1 
ATOM 511  O O   . SER A 1 514 ? 151.156 137.192 172.083 1.00 56.97  ? 530 SER A O   1 
ATOM 512  C CB  . SER A 1 514 ? 151.485 134.631 170.655 1.00 60.85  ? 530 SER A CB  1 
ATOM 513  O OG  . SER A 1 514 ? 150.746 133.869 171.594 1.00 55.93  ? 530 SER A OG  1 
ATOM 514  N N   . ASN A 1 515 ? 148.990 136.963 171.491 1.00 58.63  ? 531 ASN A N   1 
ATOM 515  C CA  . ASN A 1 515 ? 148.473 137.738 172.612 1.00 61.53  ? 531 ASN A CA  1 
ATOM 516  C C   . ASN A 1 515 ? 146.978 137.486 172.716 1.00 59.24  ? 531 ASN A C   1 
ATOM 517  O O   . ASN A 1 515 ? 146.252 137.649 171.730 1.00 59.68  ? 531 ASN A O   1 
ATOM 518  C CB  . ASN A 1 515 ? 148.759 139.233 172.432 1.00 60.08  ? 531 ASN A CB  1 
ATOM 519  C CG  . ASN A 1 515 ? 148.394 140.047 173.657 1.00 61.06  ? 531 ASN A CG  1 
ATOM 520  O OD1 . ASN A 1 515 ? 147.274 140.543 173.777 1.00 58.80  ? 531 ASN A OD1 1 
ATOM 521  N ND2 . ASN A 1 515 ? 149.342 140.189 174.576 1.00 60.34  ? 531 ASN A ND2 1 
ATOM 522  N N   . ALA A 1 516 ? 146.521 137.095 173.906 1.00 58.51  ? 532 ALA A N   1 
ATOM 523  C CA  . ALA A 1 516 ? 145.133 136.710 174.133 1.00 59.79  ? 532 ALA A CA  1 
ATOM 524  C C   . ALA A 1 516 ? 144.348 137.782 174.879 1.00 56.89  ? 532 ALA A C   1 
ATOM 525  O O   . ALA A 1 516 ? 143.486 137.458 175.702 1.00 57.86  ? 532 ALA A O   1 
ATOM 526  C CB  . ALA A 1 516 ? 145.075 135.385 174.892 1.00 59.76  ? 532 ALA A CB  1 
ATOM 527  N N   . THR A 1 517 ? 144.625 139.054 174.609 1.00 58.76  ? 533 THR A N   1 
ATOM 528  C CA  . THR A 1 517 ? 143.947 140.164 175.262 1.00 62.63  ? 533 THR A CA  1 
ATOM 529  C C   . THR A 1 517 ? 143.472 141.171 174.223 1.00 62.85  ? 533 THR A C   1 
ATOM 530  O O   . THR A 1 517 ? 144.161 141.431 173.232 1.00 64.02  ? 533 THR A O   1 
ATOM 531  C CB  . THR A 1 517 ? 144.868 140.862 176.266 1.00 66.81  ? 533 THR A CB  1 
ATOM 532  O OG1 . THR A 1 517 ? 145.982 141.440 175.574 1.00 70.64  ? 533 THR A OG1 1 
ATOM 533  C CG2 . THR A 1 517 ? 145.377 139.872 177.302 1.00 64.54  ? 533 THR A CG2 1 
ATOM 534  N N   . GLY A 1 518 ? 142.290 141.735 174.459 1.00 60.62  ? 534 GLY A N   1 
ATOM 535  C CA  . GLY A 1 518 ? 141.766 142.762 173.586 1.00 60.84  ? 534 GLY A CA  1 
ATOM 536  C C   . GLY A 1 518 ? 141.176 142.200 172.301 1.00 61.06  ? 534 GLY A C   1 
ATOM 537  O O   . GLY A 1 518 ? 141.041 140.991 172.104 1.00 62.83  ? 534 GLY A O   1 
ATOM 538  N N   . GLN A 1 519 ? 140.821 143.125 171.415 1.00 53.97  ? 535 GLN A N   1 
ATOM 539  C CA  . GLN A 1 519 ? 140.223 142.792 170.133 1.00 52.49  ? 535 GLN A CA  1 
ATOM 540  C C   . GLN A 1 519 ? 141.147 143.195 168.987 1.00 60.11  ? 535 GLN A C   1 
ATOM 541  O O   . GLN A 1 519 ? 142.045 144.027 169.139 1.00 64.71  ? 535 GLN A O   1 
ATOM 542  C CB  . GLN A 1 519 ? 138.868 143.485 169.978 1.00 48.19  ? 535 GLN A CB  1 
ATOM 543  C CG  . GLN A 1 519 ? 138.924 144.996 170.136 1.00 52.15  ? 535 GLN A CG  1 
ATOM 544  C CD  . GLN A 1 519 ? 137.615 145.670 169.776 1.00 52.17  ? 535 GLN A CD  1 
ATOM 545  O OE1 . GLN A 1 519 ? 136.780 145.097 169.077 1.00 53.55  ? 535 GLN A OE1 1 
ATOM 546  N NE2 . GLN A 1 519 ? 137.429 146.895 170.254 1.00 53.23  ? 535 GLN A NE2 1 
ATOM 547  N N   . ARG A 1 520 ? 140.912 142.586 167.828 1.00 58.56  ? 536 ARG A N   1 
ATOM 548  C CA  . ARG A 1 520 ? 141.639 142.902 166.608 1.00 50.38  ? 536 ARG A CA  1 
ATOM 549  C C   . ARG A 1 520 ? 140.636 143.269 165.524 1.00 49.17  ? 536 ARG A C   1 
ATOM 550  O O   . ARG A 1 520 ? 139.515 142.755 165.492 1.00 54.81  ? 536 ARG A O   1 
ATOM 551  C CB  . ARG A 1 520 ? 142.509 141.726 166.145 1.00 52.15  ? 536 ARG A CB  1 
ATOM 552  C CG  . ARG A 1 520 ? 143.377 141.119 167.237 1.00 53.30  ? 536 ARG A CG  1 
ATOM 553  C CD  . ARG A 1 520 ? 144.397 142.110 167.768 1.00 53.49  ? 536 ARG A CD  1 
ATOM 554  N NE  . ARG A 1 520 ? 145.258 141.513 168.783 1.00 56.65  ? 536 ARG A NE  1 
ATOM 555  C CZ  . ARG A 1 520 ? 144.967 141.450 170.076 1.00 56.30  ? 536 ARG A CZ  1 
ATOM 556  N NH1 . ARG A 1 520 ? 143.838 141.943 170.558 1.00 58.33  ? 536 ARG A NH1 1 
ATOM 557  N NH2 . ARG A 1 520 ? 145.831 140.876 170.907 1.00 54.74  ? 536 ARG A NH2 1 
ATOM 558  N N   . MET A 1 521 ? 141.050 144.167 164.632 1.00 47.90  ? 537 MET A N   1 
ATOM 559  C CA  . MET A 1 521 ? 140.168 144.701 163.605 1.00 45.59  ? 537 MET A CA  1 
ATOM 560  C C   . MET A 1 521 ? 140.790 144.529 162.229 1.00 44.94  ? 537 MET A C   1 
ATOM 561  O O   . MET A 1 521 ? 141.994 144.736 162.047 1.00 56.69  ? 537 MET A O   1 
ATOM 562  C CB  . MET A 1 521 ? 139.875 146.186 163.842 1.00 44.99  ? 537 MET A CB  1 
ATOM 563  C CG  . MET A 1 521 ? 138.740 146.732 162.990 1.00 44.91  ? 537 MET A CG  1 
ATOM 564  S SD  . MET A 1 521 ? 138.587 148.526 163.075 1.00 69.17  ? 537 MET A SD  1 
ATOM 565  C CE  . MET A 1 521 ? 140.022 149.033 162.129 1.00 52.85  ? 537 MET A CE  1 
ATOM 566  N N   . LEU A 1 522 ? 139.958 144.147 161.266 1.00 38.21  ? 538 LEU A N   1 
ATOM 567  C CA  . LEU A 1 522 ? 140.313 144.146 159.854 1.00 29.66  ? 538 LEU A CA  1 
ATOM 568  C C   . LEU A 1 522 ? 139.333 145.047 159.118 1.00 26.63  ? 538 LEU A C   1 
ATOM 569  O O   . LEU A 1 522 ? 138.116 144.849 159.207 1.00 38.89  ? 538 LEU A O   1 
ATOM 570  C CB  . LEU A 1 522 ? 140.283 142.727 159.279 1.00 30.68  ? 538 LEU A CB  1 
ATOM 571  C CG  . LEU A 1 522 ? 140.741 142.558 157.827 1.00 33.68  ? 538 LEU A CG  1 
ATOM 572  C CD1 . LEU A 1 522 ? 141.197 141.130 157.581 1.00 40.55  ? 538 LEU A CD1 1 
ATOM 573  C CD2 . LEU A 1 522 ? 139.644 142.938 156.840 1.00 35.27  ? 538 LEU A CD2 1 
ATOM 574  N N   . ARG A 1 523 ? 139.860 146.032 158.396 1.00 35.74  ? 539 ARG A N   1 
ATOM 575  C CA  . ARG A 1 523 ? 139.022 147.027 157.747 1.00 35.22  ? 539 ARG A CA  1 
ATOM 576  C C   . ARG A 1 523 ? 139.716 147.526 156.490 1.00 33.17  ? 539 ARG A C   1 
ATOM 577  O O   . ARG A 1 523 ? 140.944 147.639 156.445 1.00 51.91  ? 539 ARG A O   1 
ATOM 578  C CB  . ARG A 1 523 ? 138.728 148.198 158.690 1.00 27.65  ? 539 ARG A CB  1 
ATOM 579  C CG  . ARG A 1 523 ? 137.516 149.026 158.310 1.00 33.39  ? 539 ARG A CG  1 
ATOM 580  C CD  . ARG A 1 523 ? 137.442 150.288 159.152 1.00 34.83  ? 539 ARG A CD  1 
ATOM 581  N NE  . ARG A 1 523 ? 136.073 150.737 159.368 1.00 40.51  ? 539 ARG A NE  1 
ATOM 582  C CZ  . ARG A 1 523 ? 135.738 151.787 160.105 1.00 43.57  ? 539 ARG A CZ  1 
ATOM 583  N NH1 . ARG A 1 523 ? 136.652 152.532 160.706 1.00 46.78  ? 539 ARG A NH1 1 
ATOM 584  N NH2 . ARG A 1 523 ? 134.452 152.098 160.245 1.00 33.48  ? 539 ARG A NH2 1 
ATOM 585  N N   . ILE A 1 524 ? 138.915 147.825 155.471 1.00 3.81   ? 540 ILE A N   1 
ATOM 586  C CA  . ILE A 1 524 ? 139.401 148.352 154.202 1.00 14.96  ? 540 ILE A CA  1 
ATOM 587  C C   . ILE A 1 524 ? 138.645 149.640 153.910 1.00 20.96  ? 540 ILE A C   1 
ATOM 588  O O   . ILE A 1 524 ? 137.413 149.677 154.005 1.00 26.87  ? 540 ILE A O   1 
ATOM 589  C CB  . ILE A 1 524 ? 139.229 147.335 153.059 1.00 18.46  ? 540 ILE A CB  1 
ATOM 590  C CG1 . ILE A 1 524 ? 139.940 146.027 153.417 1.00 22.82  ? 540 ILE A CG1 1 
ATOM 591  C CG2 . ILE A 1 524 ? 139.776 147.901 151.755 1.00 25.00  ? 540 ILE A CG2 1 
ATOM 592  C CD1 . ILE A 1 524 ? 139.871 144.969 152.341 1.00 28.47  ? 540 ILE A CD1 1 
ATOM 593  N N   . LEU A 1 525 ? 139.383 150.690 153.564 1.00 36.92  ? 541 LEU A N   1 
ATOM 594  C CA  . LEU A 1 525 ? 138.816 151.998 153.278 1.00 22.96  ? 541 LEU A CA  1 
ATOM 595  C C   . LEU A 1 525 ? 139.027 152.352 151.813 1.00 27.03  ? 541 LEU A C   1 
ATOM 596  O O   . LEU A 1 525 ? 140.035 151.977 151.208 1.00 38.31  ? 541 LEU A O   1 
ATOM 597  C CB  . LEU A 1 525 ? 139.451 153.072 154.165 1.00 27.27  ? 541 LEU A CB  1 
ATOM 598  C CG  . LEU A 1 525 ? 139.341 152.853 155.674 1.00 32.62  ? 541 LEU A CG  1 
ATOM 599  C CD1 . LEU A 1 525 ? 140.147 153.902 156.419 1.00 44.48  ? 541 LEU A CD1 1 
ATOM 600  C CD2 . LEU A 1 525 ? 137.890 152.880 156.117 1.00 29.07  ? 541 LEU A CD2 1 
ATOM 601  N N   . LYS A 1 526 ? 138.067 153.078 151.248 1.00 22.21  ? 542 LYS A N   1 
ATOM 602  C CA  . LYS A 1 526 ? 138.145 153.565 149.878 1.00 25.92  ? 542 LYS A CA  1 
ATOM 603  C C   . LYS A 1 526 ? 138.307 155.078 149.896 1.00 41.76  ? 542 LYS A C   1 
ATOM 604  O O   . LYS A 1 526 ? 137.488 155.787 150.491 1.00 48.26  ? 542 LYS A O   1 
ATOM 605  C CB  . LYS A 1 526 ? 136.896 153.175 149.083 1.00 25.50  ? 542 LYS A CB  1 
ATOM 606  C CG  . LYS A 1 526 ? 136.911 153.637 147.634 1.00 24.79  ? 542 LYS A CG  1 
ATOM 607  C CD  . LYS A 1 526 ? 135.613 153.291 146.924 1.00 32.73  ? 542 LYS A CD  1 
ATOM 608  C CE  . LYS A 1 526 ? 135.609 153.804 145.495 1.00 35.82  ? 542 LYS A CE  1 
ATOM 609  N NZ  . LYS A 1 526 ? 134.331 153.497 144.794 1.00 38.48  ? 542 LYS A NZ  1 
ATOM 610  N N   . ASN A 1 527 ? 139.362 155.566 149.245 1.00 44.11  ? 543 ASN A N   1 
ATOM 611  C CA  . ASN A 1 527 ? 139.646 156.999 149.185 1.00 31.45  ? 543 ASN A CA  1 
ATOM 612  C C   . ASN A 1 527 ? 139.740 157.599 150.585 1.00 31.77  ? 543 ASN A C   1 
ATOM 613  O O   . ASN A 1 527 ? 139.383 158.757 150.813 1.00 45.40  ? 543 ASN A O   1 
ATOM 614  C CB  . ASN A 1 527 ? 138.595 157.732 148.350 1.00 34.92  ? 543 ASN A CB  1 
ATOM 615  C CG  . ASN A 1 527 ? 138.592 157.292 146.900 1.00 41.46  ? 543 ASN A CG  1 
ATOM 616  O OD1 . ASN A 1 527 ? 139.616 156.866 146.368 1.00 38.85  ? 543 ASN A OD1 1 
ATOM 617  N ND2 . ASN A 1 527 ? 137.438 157.395 146.252 1.00 42.14  ? 543 ASN A ND2 1 
ATOM 618  N N   . GLY A 1 528 ? 140.227 156.804 151.535 1.00 33.61  ? 544 GLY A N   1 
ATOM 619  C CA  . GLY A 1 528 ? 140.402 157.269 152.895 1.00 36.85  ? 544 GLY A CA  1 
ATOM 620  C C   . GLY A 1 528 ? 139.133 157.387 153.707 1.00 33.11  ? 544 GLY A C   1 
ATOM 621  O O   . GLY A 1 528 ? 139.169 157.972 154.796 1.00 37.37  ? 544 GLY A O   1 
ATOM 622  N N   . THR A 1 529 ? 138.014 156.856 153.220 1.00 29.38  ? 545 THR A N   1 
ATOM 623  C CA  . THR A 1 529 ? 136.745 156.946 153.925 1.00 37.56  ? 545 THR A CA  1 
ATOM 624  C C   . THR A 1 529 ? 135.952 155.667 153.701 1.00 36.15  ? 545 THR A C   1 
ATOM 625  O O   . THR A 1 529 ? 136.335 154.799 152.912 1.00 40.41  ? 545 THR A O   1 
ATOM 626  C CB  . THR A 1 529 ? 135.932 158.165 153.469 1.00 41.55  ? 545 THR A CB  1 
ATOM 627  O OG1 . THR A 1 529 ? 134.711 158.237 154.218 1.00 42.12  ? 545 THR A OG1 1 
ATOM 628  C CG2 . THR A 1 529 ? 135.609 158.073 151.986 1.00 38.30  ? 545 THR A CG2 1 
ATOM 629  N N   . TYR A 1 530 ? 134.832 155.559 154.411 1.00 33.34  ? 546 TYR A N   1 
ATOM 630  C CA  . TYR A 1 530 ? 133.994 154.373 154.318 1.00 39.40  ? 546 TYR A CA  1 
ATOM 631  C C   . TYR A 1 530 ? 133.355 154.280 152.938 1.00 43.61  ? 546 TYR A C   1 
ATOM 632  O O   . TYR A 1 530 ? 133.111 155.294 152.278 1.00 43.85  ? 546 TYR A O   1 
ATOM 633  C CB  . TYR A 1 530 ? 132.907 154.405 155.393 1.00 41.15  ? 546 TYR A CB  1 
ATOM 634  C CG  . TYR A 1 530 ? 133.419 154.668 156.793 1.00 42.39  ? 546 TYR A CG  1 
ATOM 635  C CD1 . TYR A 1 530 ? 134.721 154.347 157.154 1.00 42.03  ? 546 TYR A CD1 1 
ATOM 636  C CD2 . TYR A 1 530 ? 132.597 155.240 157.755 1.00 43.69  ? 546 TYR A CD2 1 
ATOM 637  C CE1 . TYR A 1 530 ? 135.189 154.588 158.432 1.00 44.16  ? 546 TYR A CE1 1 
ATOM 638  C CE2 . TYR A 1 530 ? 133.055 155.484 159.035 1.00 47.99  ? 546 TYR A CE2 1 
ATOM 639  C CZ  . TYR A 1 530 ? 134.352 155.156 159.368 1.00 51.95  ? 546 TYR A CZ  1 
ATOM 640  O OH  . TYR A 1 530 ? 134.812 155.398 160.642 1.00 54.32  ? 546 TYR A OH  1 
ATOM 641  N N   . SER A 1 531 ? 133.083 153.052 152.502 1.00 33.19  ? 547 SER A N   1 
ATOM 642  C CA  . SER A 1 531 ? 132.440 152.826 151.216 1.00 32.05  ? 547 SER A CA  1 
ATOM 643  C C   . SER A 1 531 ? 131.628 151.542 151.281 1.00 39.42  ? 547 SER A C   1 
ATOM 644  O O   . SER A 1 531 ? 131.866 150.673 152.124 1.00 40.58  ? 547 SER A O   1 
ATOM 645  C CB  . SER A 1 531 ? 133.463 152.754 150.078 1.00 30.35  ? 547 SER A CB  1 
ATOM 646  O OG  . SER A 1 531 ? 132.823 152.532 148.833 1.00 28.91  ? 547 SER A OG  1 
ATOM 647  N N   . ILE A 1 532 ? 130.657 151.435 150.371 1.00 44.90  ? 548 ILE A N   1 
ATOM 648  C CA  . ILE A 1 532 ? 129.773 150.278 150.357 1.00 33.59  ? 548 ILE A CA  1 
ATOM 649  C C   . ILE A 1 532 ? 130.508 149.068 149.797 1.00 34.08  ? 548 ILE A C   1 
ATOM 650  O O   . ILE A 1 532 ? 131.340 149.183 148.888 1.00 40.69  ? 548 ILE A O   1 
ATOM 651  C CB  . ILE A 1 532 ? 128.506 150.585 149.539 1.00 37.82  ? 548 ILE A CB  1 
ATOM 652  C CG1 . ILE A 1 532 ? 127.512 149.423 149.620 1.00 40.80  ? 548 ILE A CG1 1 
ATOM 653  C CG2 . ILE A 1 532 ? 128.859 150.860 148.083 1.00 40.27  ? 548 ILE A CG2 1 
ATOM 654  C CD1 . ILE A 1 532 ? 127.025 149.125 151.019 1.00 42.65  ? 548 ILE A CD1 1 
ATOM 655  N N   . GLY A 1 533 ? 130.196 147.894 150.343 1.00 30.30  ? 549 GLY A N   1 
ATOM 656  C CA  . GLY A 1 533 ? 130.722 146.645 149.839 1.00 32.78  ? 549 GLY A CA  1 
ATOM 657  C C   . GLY A 1 533 ? 132.088 146.250 150.356 1.00 33.12  ? 549 GLY A C   1 
ATOM 658  O O   . GLY A 1 533 ? 132.633 145.238 149.897 1.00 42.45  ? 549 GLY A O   1 
ATOM 659  N N   . LEU A 1 534 ? 132.662 147.004 151.290 1.00 23.33  ? 550 LEU A N   1 
ATOM 660  C CA  . LEU A 1 534 ? 133.979 146.685 151.816 1.00 21.84  ? 550 LEU A CA  1 
ATOM 661  C C   . LEU A 1 534 ? 133.871 145.853 153.087 1.00 21.04  ? 550 LEU A C   1 
ATOM 662  O O   . LEU A 1 534 ? 132.881 145.939 153.820 1.00 24.27  ? 550 LEU A O   1 
ATOM 663  C CB  . LEU A 1 534 ? 134.755 147.968 152.098 1.00 27.41  ? 550 LEU A CB  1 
ATOM 664  C CG  . LEU A 1 534 ? 135.058 148.836 150.875 1.00 27.35  ? 550 LEU A CG  1 
ATOM 665  C CD1 . LEU A 1 534 ? 135.753 150.115 151.295 1.00 30.81  ? 550 LEU A CD1 1 
ATOM 666  C CD2 . LEU A 1 534 ? 135.904 148.080 149.862 1.00 25.87  ? 550 LEU A CD2 1 
ATOM 667  N N   . PRO A 1 535 ? 134.878 145.034 153.378 1.00 14.52  ? 551 PRO A N   1 
ATOM 668  C CA  . PRO A 1 535 ? 134.816 144.171 154.559 1.00 18.28  ? 551 PRO A CA  1 
ATOM 669  C C   . PRO A 1 535 ? 135.049 144.935 155.853 1.00 20.27  ? 551 PRO A C   1 
ATOM 670  O O   . PRO A 1 535 ? 135.552 146.060 155.871 1.00 28.19  ? 551 PRO A O   1 
ATOM 671  C CB  . PRO A 1 535 ? 135.939 143.158 154.312 1.00 19.21  ? 551 PRO A CB  1 
ATOM 672  C CG  . PRO A 1 535 ? 136.916 143.892 153.478 1.00 25.87  ? 551 PRO A CG  1 
ATOM 673  C CD  . PRO A 1 535 ? 136.107 144.806 152.599 1.00 14.96  ? 551 PRO A CD  1 
ATOM 674  N N   . TYR A 1 536 ? 134.668 144.287 156.951 1.00 24.33  ? 552 TYR A N   1 
ATOM 675  C CA  . TYR A 1 536 ? 134.854 144.835 158.288 1.00 24.23  ? 552 TYR A CA  1 
ATOM 676  C C   . TYR A 1 536 ? 134.674 143.696 159.277 1.00 27.71  ? 552 TYR A C   1 
ATOM 677  O O   . TYR A 1 536 ? 133.665 142.986 159.221 1.00 47.30  ? 552 TYR A O   1 
ATOM 678  C CB  . TYR A 1 536 ? 133.852 145.964 158.566 1.00 34.04  ? 552 TYR A CB  1 
ATOM 679  C CG  . TYR A 1 536 ? 134.121 146.774 159.820 1.00 32.22  ? 552 TYR A CG  1 
ATOM 680  C CD1 . TYR A 1 536 ? 135.272 146.581 160.576 1.00 41.27  ? 552 TYR A CD1 1 
ATOM 681  C CD2 . TYR A 1 536 ? 133.214 147.733 160.249 1.00 28.13  ? 552 TYR A CD2 1 
ATOM 682  C CE1 . TYR A 1 536 ? 135.509 147.322 161.717 1.00 42.61  ? 552 TYR A CE1 1 
ATOM 683  C CE2 . TYR A 1 536 ? 133.444 148.477 161.389 1.00 29.80  ? 552 TYR A CE2 1 
ATOM 684  C CZ  . TYR A 1 536 ? 134.592 148.268 162.119 1.00 36.54  ? 552 TYR A CZ  1 
ATOM 685  O OH  . TYR A 1 536 ? 134.824 149.007 163.255 1.00 44.64  ? 552 TYR A OH  1 
ATOM 686  N N   . THR A 1 537 ? 135.648 143.511 160.166 1.00 27.20  ? 553 THR A N   1 
ATOM 687  C CA  . THR A 1 537 ? 135.624 142.396 161.099 1.00 32.69  ? 553 THR A CA  1 
ATOM 688  C C   . THR A 1 537 ? 136.287 142.785 162.411 1.00 38.93  ? 553 THR A C   1 
ATOM 689  O O   . THR A 1 537 ? 137.360 143.393 162.420 1.00 45.24  ? 553 THR A O   1 
ATOM 690  C CB  . THR A 1 537 ? 136.333 141.167 160.514 1.00 40.86  ? 553 THR A CB  1 
ATOM 691  O OG1 . THR A 1 537 ? 135.725 140.806 159.268 1.00 38.51  ? 553 THR A OG1 1 
ATOM 692  C CG2 . THR A 1 537 ? 136.250 139.990 161.476 1.00 42.06  ? 553 THR A CG2 1 
ATOM 693  N N   . ARG A 1 538 ? 135.635 142.425 163.515 1.00 46.78  ? 554 ARG A N   1 
ATOM 694  C CA  . ARG A 1 538 ? 136.206 142.515 164.851 1.00 42.56  ? 554 ARG A CA  1 
ATOM 695  C C   . ARG A 1 538 ? 135.902 141.221 165.590 1.00 47.01  ? 554 ARG A C   1 
ATOM 696  O O   . ARG A 1 538 ? 134.804 140.671 165.463 1.00 53.84  ? 554 ARG A O   1 
ATOM 697  C CB  . ARG A 1 538 ? 135.644 143.704 165.642 1.00 43.14  ? 554 ARG A CB  1 
ATOM 698  C CG  . ARG A 1 538 ? 135.899 145.066 165.018 1.00 47.88  ? 554 ARG A CG  1 
ATOM 699  C CD  . ARG A 1 538 ? 135.154 146.156 165.776 1.00 44.56  ? 554 ARG A CD  1 
ATOM 700  N NE  . ARG A 1 538 ? 135.452 147.491 165.269 1.00 38.85  ? 554 ARG A NE  1 
ATOM 701  C CZ  . ARG A 1 538 ? 136.423 148.272 165.725 1.00 40.61  ? 554 ARG A CZ  1 
ATOM 702  N NH1 . ARG A 1 538 ? 137.223 147.884 166.705 1.00 44.91  ? 554 ARG A NH1 1 
ATOM 703  N NH2 . ARG A 1 538 ? 136.595 149.475 165.184 1.00 48.37  ? 554 ARG A NH2 1 
ATOM 704  N N   . ASP A 1 539 ? 136.873 140.736 166.359 1.00 43.15  ? 555 ASP A N   1 
ATOM 705  C CA  . ASP A 1 539 ? 136.692 139.490 167.089 1.00 51.19  ? 555 ASP A CA  1 
ATOM 706  C C   . ASP A 1 539 ? 137.645 139.460 168.273 1.00 47.15  ? 555 ASP A C   1 
ATOM 707  O O   . ASP A 1 539 ? 138.618 140.217 168.333 1.00 44.54  ? 555 ASP A O   1 
ATOM 708  C CB  . ASP A 1 539 ? 136.919 138.274 166.184 1.00 51.54  ? 555 ASP A CB  1 
ATOM 709  C CG  . ASP A 1 539 ? 138.292 138.274 165.544 1.00 51.93  ? 555 ASP A CG  1 
ATOM 710  O OD1 . ASP A 1 539 ? 139.286 138.042 166.265 1.00 53.14  ? 555 ASP A OD1 1 
ATOM 711  O OD2 . ASP A 1 539 ? 138.378 138.507 164.321 1.00 47.14  ? 555 ASP A OD2 1 
ATOM 712  N N   . VAL A 1 540 ? 137.346 138.569 169.218 1.00 47.72  ? 556 VAL A N   1 
ATOM 713  C CA  . VAL A 1 540 ? 138.201 138.393 170.385 1.00 51.15  ? 556 VAL A CA  1 
ATOM 714  C C   . VAL A 1 540 ? 139.525 137.787 169.944 1.00 53.72  ? 556 VAL A C   1 
ATOM 715  O O   . VAL A 1 540 ? 139.584 137.016 168.977 1.00 58.19  ? 556 VAL A O   1 
ATOM 716  C CB  . VAL A 1 540 ? 137.504 137.513 171.434 1.00 51.64  ? 556 VAL A CB  1 
ATOM 717  C CG1 . VAL A 1 540 ? 138.401 137.321 172.648 1.00 53.29  ? 556 VAL A CG1 1 
ATOM 718  C CG2 . VAL A 1 540 ? 136.175 138.126 171.843 1.00 53.20  ? 556 VAL A CG2 1 
ATOM 719  N N   . ALA A 1 541 ? 140.597 138.134 170.652 1.00 56.07  ? 557 ALA A N   1 
ATOM 720  C CA  . ALA A 1 541 ? 141.929 137.701 170.257 1.00 57.68  ? 557 ALA A CA  1 
ATOM 721  C C   . ALA A 1 541 ? 142.404 136.539 171.119 1.00 57.24  ? 557 ALA A C   1 
ATOM 722  O O   . ALA A 1 541 ? 142.426 136.629 172.350 1.00 62.17  ? 557 ALA A O   1 
ATOM 723  C CB  . ALA A 1 541 ? 142.912 138.865 170.361 1.00 57.94  ? 557 ALA A CB  1 
ATOM 724  N N   . ILE A 1 542 ? 142.779 135.443 170.464 1.00 50.65  ? 558 ILE A N   1 
ATOM 725  C CA  . ILE A 1 542 ? 143.457 134.322 171.104 1.00 53.11  ? 558 ILE A CA  1 
ATOM 726  C C   . ILE A 1 542 ? 144.659 133.953 170.248 1.00 54.21  ? 558 ILE A C   1 
ATOM 727  O O   . ILE A 1 542 ? 144.545 133.826 169.024 1.00 61.71  ? 558 ILE A O   1 
ATOM 728  C CB  . ILE A 1 542 ? 142.522 133.108 171.297 1.00 55.79  ? 558 ILE A CB  1 
ATOM 729  C CG1 . ILE A 1 542 ? 141.508 133.400 172.410 1.00 59.76  ? 558 ILE A CG1 1 
ATOM 730  C CG2 . ILE A 1 542 ? 143.339 131.849 171.605 1.00 56.67  ? 558 ILE A CG2 1 
ATOM 731  C CD1 . ILE A 1 542 ? 140.581 132.242 172.744 1.00 58.84  ? 558 ILE A CD1 1 
ATOM 732  N N   . SER A 1 543 ? 145.810 133.776 170.893 1.00 58.80  ? 559 SER A N   1 
ATOM 733  C CA  . SER A 1 543 ? 147.074 133.477 170.209 1.00 60.55  ? 559 SER A CA  1 
ATOM 734  C C   . SER A 1 543 ? 147.305 134.584 169.179 1.00 53.04  ? 559 SER A C   1 
ATOM 735  O O   . SER A 1 543 ? 147.216 135.768 169.534 1.00 56.74  ? 559 SER A O   1 
ATOM 736  C CB  . SER A 1 543 ? 147.024 132.060 169.652 1.00 61.73  ? 559 SER A CB  1 
ATOM 737  O OG  . SER A 1 543 ? 146.054 131.943 168.626 1.00 61.46  ? 559 SER A OG  1 
ATOM 738  N N   . THR A 1 544 ? 147.596 134.261 167.920 1.00 45.22  ? 560 THR A N   1 
ATOM 739  C CA  . THR A 1 544 ? 147.831 135.277 166.903 1.00 49.53  ? 560 THR A CA  1 
ATOM 740  C C   . THR A 1 544 ? 146.548 135.929 166.404 1.00 51.20  ? 560 THR A C   1 
ATOM 741  O O   . THR A 1 544 ? 146.615 137.014 165.815 1.00 52.43  ? 560 THR A O   1 
ATOM 742  C CB  . THR A 1 544 ? 148.584 134.666 165.720 1.00 51.44  ? 560 THR A CB  1 
ATOM 743  O OG1 . THR A 1 544 ? 147.837 133.563 165.192 1.00 62.22  ? 560 THR A OG1 1 
ATOM 744  C CG2 . THR A 1 544 ? 149.956 134.182 166.159 1.00 46.80  ? 560 THR A CG2 1 
ATOM 745  N N   . ALA A 1 545 ? 145.394 135.304 166.624 1.00 51.67  ? 561 ALA A N   1 
ATOM 746  C CA  . ALA A 1 545 ? 144.106 135.847 166.208 1.00 52.65  ? 561 ALA A CA  1 
ATOM 747  C C   . ALA A 1 545 ? 144.130 136.326 164.761 1.00 51.15  ? 561 ALA A C   1 
ATOM 748  O O   . ALA A 1 545 ? 143.902 137.515 164.502 1.00 53.30  ? 561 ALA A O   1 
ATOM 749  C CB  . ALA A 1 545 ? 143.699 136.999 167.128 1.00 52.91  ? 561 ALA A CB  1 
ATOM 750  N N   . PRO A 1 546 ? 144.399 135.450 163.793 1.00 44.80  ? 562 PRO A N   1 
ATOM 751  C CA  . PRO A 1 546 ? 144.337 135.874 162.390 1.00 35.94  ? 562 PRO A CA  1 
ATOM 752  C C   . PRO A 1 546 ? 142.937 136.331 162.009 1.00 46.20  ? 562 PRO A C   1 
ATOM 753  O O   . PRO A 1 546 ? 141.936 135.844 162.541 1.00 55.79  ? 562 PRO A O   1 
ATOM 754  C CB  . PRO A 1 546 ? 144.745 134.614 161.619 1.00 45.13  ? 562 PRO A CB  1 
ATOM 755  C CG  . PRO A 1 546 ? 145.498 133.793 162.592 1.00 52.32  ? 562 PRO A CG  1 
ATOM 756  C CD  . PRO A 1 546 ? 144.860 134.057 163.917 1.00 49.71  ? 562 PRO A CD  1 
ATOM 757  N N   . GLN A 1 547 ? 142.875 137.281 161.077 1.00 41.92  ? 563 GLN A N   1 
ATOM 758  C CA  . GLN A 1 547 ? 141.611 137.803 160.577 1.00 37.37  ? 563 GLN A CA  1 
ATOM 759  C C   . GLN A 1 547 ? 141.643 137.823 159.057 1.00 27.67  ? 563 GLN A C   1 
ATOM 760  O O   . GLN A 1 547 ? 142.631 138.258 158.459 1.00 33.33  ? 563 GLN A O   1 
ATOM 761  C CB  . GLN A 1 547 ? 141.340 139.213 161.113 1.00 42.29  ? 563 GLN A CB  1 
ATOM 762  C CG  . GLN A 1 547 ? 141.045 139.265 162.599 1.00 49.45  ? 563 GLN A CG  1 
ATOM 763  C CD  . GLN A 1 547 ? 140.711 140.664 163.075 1.00 50.87  ? 563 GLN A CD  1 
ATOM 764  O OE1 . GLN A 1 547 ? 141.457 141.611 162.827 1.00 47.50  ? 563 GLN A OE1 1 
ATOM 765  N NE2 . GLN A 1 547 ? 139.579 140.803 163.755 1.00 54.15  ? 563 GLN A NE2 1 
ATOM 766  N N   . ASN A 1 548 ? 140.558 137.362 158.439 1.00 23.65  ? 564 ASN A N   1 
ATOM 767  C CA  . ASN A 1 548 ? 140.435 137.304 156.990 1.00 27.89  ? 564 ASN A CA  1 
ATOM 768  C C   . ASN A 1 548 ? 139.135 137.967 156.560 1.00 29.49  ? 564 ASN A C   1 
ATOM 769  O O   . ASN A 1 548 ? 138.120 137.875 157.257 1.00 40.89  ? 564 ASN A O   1 
ATOM 770  C CB  . ASN A 1 548 ? 140.472 135.856 156.488 1.00 27.70  ? 564 ASN A CB  1 
ATOM 771  C CG  . ASN A 1 548 ? 140.164 135.743 155.008 1.00 32.23  ? 564 ASN A CG  1 
ATOM 772  O OD1 . ASN A 1 548 ? 139.020 135.519 154.615 1.00 35.97  ? 564 ASN A OD1 1 
ATOM 773  N ND2 . ASN A 1 548 ? 141.188 135.901 154.177 1.00 34.07  ? 564 ASN A ND2 1 
ATOM 774  N N   . GLY A 1 549 ? 139.172 138.632 155.409 1.00 23.62  ? 565 GLY A N   1 
ATOM 775  C CA  . GLY A 1 549 ? 137.989 139.277 154.873 1.00 19.75  ? 565 GLY A CA  1 
ATOM 776  C C   . GLY A 1 549 ? 138.088 139.418 153.370 1.00 23.67  ? 565 GLY A C   1 
ATOM 777  O O   . GLY A 1 549 ? 139.181 139.437 152.795 1.00 37.30  ? 565 GLY A O   1 
ATOM 778  N N   . THR A 1 550 ? 136.921 139.517 152.736 1.00 13.80  ? 566 THR A N   1 
ATOM 779  C CA  . THR A 1 550 ? 136.842 139.664 151.290 1.00 16.90  ? 566 THR A CA  1 
ATOM 780  C C   . THR A 1 550 ? 135.683 140.586 150.947 1.00 14.58  ? 566 THR A C   1 
ATOM 781  O O   . THR A 1 550 ? 134.623 140.524 151.576 1.00 21.65  ? 566 THR A O   1 
ATOM 782  C CB  . THR A 1 550 ? 136.662 138.309 150.596 1.00 24.85  ? 566 THR A CB  1 
ATOM 783  O OG1 . THR A 1 550 ? 137.814 137.490 150.834 1.00 43.43  ? 566 THR A OG1 1 
ATOM 784  C CG2 . THR A 1 550 ? 136.475 138.495 149.096 1.00 23.03  ? 566 THR A CG2 1 
ATOM 785  N N   . SER A 1 551 ? 135.897 141.439 149.949 1.00 24.71  ? 567 SER A N   1 
ATOM 786  C CA  . SER A 1 551 ? 134.874 142.382 149.531 1.00 17.09  ? 567 SER A CA  1 
ATOM 787  C C   . SER A 1 551 ? 134.038 141.804 148.393 1.00 21.36  ? 567 SER A C   1 
ATOM 788  O O   . SER A 1 551 ? 134.438 140.863 147.702 1.00 27.29  ? 567 SER A O   1 
ATOM 789  C CB  . SER A 1 551 ? 135.510 143.695 149.076 1.00 14.10  ? 567 SER A CB  1 
ATOM 790  O OG  . SER A 1 551 ? 136.070 143.563 147.781 1.00 24.33  ? 567 SER A OG  1 
ATOM 791  N N   . GLY A 1 552 ? 132.859 142.384 148.206 1.00 11.74  ? 568 GLY A N   1 
ATOM 792  C CA  . GLY A 1 552 ? 132.051 142.092 147.045 1.00 21.11  ? 568 GLY A CA  1 
ATOM 793  C C   . GLY A 1 552 ? 132.482 142.932 145.856 1.00 13.93  ? 568 GLY A C   1 
ATOM 794  O O   . GLY A 1 552 ? 133.372 143.780 145.931 1.00 23.97  ? 568 GLY A O   1 
ATOM 795  N N   . VAL A 1 553 ? 131.828 142.680 144.724 1.00 16.42  ? 569 VAL A N   1 
ATOM 796  C CA  . VAL A 1 553 ? 132.115 143.446 143.519 1.00 12.83  ? 569 VAL A CA  1 
ATOM 797  C C   . VAL A 1 553 ? 131.567 144.856 143.685 1.00 21.61  ? 569 VAL A C   1 
ATOM 798  O O   . VAL A 1 553 ? 130.367 145.050 143.925 1.00 35.29  ? 569 VAL A O   1 
ATOM 799  C CB  . VAL A 1 553 ? 131.519 142.753 142.285 1.00 16.22  ? 569 VAL A CB  1 
ATOM 800  C CG1 . VAL A 1 553 ? 131.948 143.470 141.018 1.00 26.64  ? 569 VAL A CG1 1 
ATOM 801  C CG2 . VAL A 1 553 ? 131.939 141.293 142.242 1.00 25.16  ? 569 VAL A CG2 1 
ATOM 802  N N   . ILE A 1 554 ? 132.443 145.848 143.558 1.00 19.71  ? 570 ILE A N   1 
ATOM 803  C CA  . ILE A 1 554 ? 132.074 147.243 143.784 1.00 27.06  ? 570 ILE A CA  1 
ATOM 804  C C   . ILE A 1 554 ? 132.573 148.096 142.623 1.00 34.79  ? 570 ILE A C   1 
ATOM 805  O O   . ILE A 1 554 ? 133.605 147.773 142.017 1.00 33.36  ? 570 ILE A O   1 
ATOM 806  C CB  . ILE A 1 554 ? 132.637 147.753 145.120 1.00 21.10  ? 570 ILE A CB  1 
ATOM 807  C CG1 . ILE A 1 554 ? 134.158 147.582 145.155 1.00 18.90  ? 570 ILE A CG1 1 
ATOM 808  C CG2 . ILE A 1 554 ? 131.995 147.010 146.277 1.00 18.84  ? 570 ILE A CG2 1 
ATOM 809  C CD1 . ILE A 1 554 ? 134.801 148.083 146.428 1.00 23.35  ? 570 ILE A CD1 1 
ATOM 810  N N   . PRO A 1 555 ? 131.886 149.183 142.279 1.00 23.46  ? 571 PRO A N   1 
ATOM 811  C CA  . PRO A 1 555 ? 132.372 150.057 141.210 1.00 22.36  ? 571 PRO A CA  1 
ATOM 812  C C   . PRO A 1 555 ? 133.524 150.935 141.669 1.00 30.45  ? 571 PRO A C   1 
ATOM 813  O O   . PRO A 1 555 ? 133.671 151.251 142.852 1.00 26.08  ? 571 PRO A O   1 
ATOM 814  C CB  . PRO A 1 555 ? 131.141 150.901 140.862 1.00 25.85  ? 571 PRO A CB  1 
ATOM 815  C CG  . PRO A 1 555 ? 130.366 150.955 142.128 1.00 31.71  ? 571 PRO A CG  1 
ATOM 816  C CD  . PRO A 1 555 ? 130.588 149.634 142.812 1.00 21.11  ? 571 PRO A CD  1 
ATOM 817  N N   . VAL A 1 556 ? 134.349 151.334 140.702 1.00 40.91  ? 572 VAL A N   1 
ATOM 818  C CA  . VAL A 1 556 ? 135.494 152.203 140.946 1.00 38.67  ? 572 VAL A CA  1 
ATOM 819  C C   . VAL A 1 556 ? 135.757 153.022 139.689 1.00 40.59  ? 572 VAL A C   1 
ATOM 820  O O   . VAL A 1 556 ? 135.215 152.749 138.616 1.00 44.27  ? 572 VAL A O   1 
ATOM 821  C CB  . VAL A 1 556 ? 136.763 151.412 141.343 1.00 34.94  ? 572 VAL A CB  1 
ATOM 822  C CG1 . VAL A 1 556 ? 136.574 150.744 142.693 1.00 37.21  ? 572 VAL A CG1 1 
ATOM 823  C CG2 . VAL A 1 556 ? 137.110 150.383 140.277 1.00 37.81  ? 572 VAL A CG2 1 
ATOM 824  N N   . LYS A 1 557 ? 136.603 154.038 139.831 1.00 45.65  ? 573 LYS A N   1 
ATOM 825  C CA  . LYS A 1 557 ? 137.037 154.867 138.718 1.00 46.67  ? 573 LYS A CA  1 
ATOM 826  C C   . LYS A 1 557 ? 138.524 155.154 138.867 1.00 47.94  ? 573 LYS A C   1 
ATOM 827  O O   . LYS A 1 557 ? 139.106 154.982 139.941 1.00 47.45  ? 573 LYS A O   1 
ATOM 828  C CB  . LYS A 1 557 ? 136.244 156.180 138.645 1.00 48.37  ? 573 LYS A CB  1 
ATOM 829  C CG  . LYS A 1 557 ? 136.335 157.034 139.900 1.00 49.23  ? 573 LYS A CG  1 
ATOM 830  C CD  . LYS A 1 557 ? 135.580 158.346 139.746 1.00 47.15  ? 573 LYS A CD  1 
ATOM 831  C CE  . LYS A 1 557 ? 134.077 158.124 139.675 1.00 50.05  ? 573 LYS A CE  1 
ATOM 832  N NZ  . LYS A 1 557 ? 133.326 159.408 139.608 1.00 57.31  ? 573 LYS A NZ  1 
ATOM 833  N N   . GLU A 1 558 ? 139.136 155.593 137.770 1.00 50.21  ? 574 GLU A N   1 
ATOM 834  C CA  . GLU A 1 558 ? 140.569 155.856 137.767 1.00 49.64  ? 574 GLU A CA  1 
ATOM 835  C C   . GLU A 1 558 ? 140.931 156.841 138.870 1.00 48.68  ? 574 GLU A C   1 
ATOM 836  O O   . GLU A 1 558 ? 140.264 157.862 139.055 1.00 56.64  ? 574 GLU A O   1 
ATOM 837  C CB  . GLU A 1 558 ? 141.000 156.403 136.405 1.00 48.12  ? 574 GLU A CB  1 
ATOM 838  C CG  . GLU A 1 558 ? 142.504 156.564 136.254 1.00 46.57  ? 574 GLU A CG  1 
ATOM 839  C CD  . GLU A 1 558 ? 142.897 157.126 134.902 1.00 58.88  ? 574 GLU A CD  1 
ATOM 840  O OE1 . GLU A 1 558 ? 141.997 157.551 134.148 1.00 59.96  ? 574 GLU A OE1 1 
ATOM 841  O OE2 . GLU A 1 558 ? 144.107 157.142 134.592 1.00 55.50  ? 574 GLU A OE2 1 
ATOM 842  N N   . GLY A 1 559 ? 141.995 156.523 139.605 1.00 40.71  ? 575 GLY A N   1 
ATOM 843  C CA  . GLY A 1 559 ? 142.435 157.338 140.716 1.00 47.04  ? 575 GLY A CA  1 
ATOM 844  C C   . GLY A 1 559 ? 141.971 156.869 142.077 1.00 51.83  ? 575 GLY A C   1 
ATOM 845  O O   . GLY A 1 559 ? 142.547 157.294 143.087 1.00 48.36  ? 575 GLY A O   1 
ATOM 846  N N   . ASP A 1 560 ? 140.953 156.015 142.143 1.00 49.88  ? 576 ASP A N   1 
ATOM 847  C CA  . ASP A 1 560 ? 140.507 155.489 143.424 1.00 43.06  ? 576 ASP A CA  1 
ATOM 848  C C   . ASP A 1 560 ? 141.562 154.559 144.011 1.00 42.03  ? 576 ASP A C   1 
ATOM 849  O O   . ASP A 1 560 ? 142.251 153.832 143.291 1.00 38.76  ? 576 ASP A O   1 
ATOM 850  C CB  . ASP A 1 560 ? 139.184 154.741 143.265 1.00 35.12  ? 576 ASP A CB  1 
ATOM 851  C CG  . ASP A 1 560 ? 138.071 155.628 142.748 1.00 49.52  ? 576 ASP A CG  1 
ATOM 852  O OD1 . ASP A 1 560 ? 138.135 156.856 142.967 1.00 55.12  ? 576 ASP A OD1 1 
ATOM 853  O OD2 . ASP A 1 560 ? 137.130 155.095 142.124 1.00 54.38  ? 576 ASP A OD2 1 
ATOM 854  N N   . TYR A 1 561 ? 141.685 154.588 145.336 1.00 36.38  ? 577 TYR A N   1 
ATOM 855  C CA  . TYR A 1 561 ? 142.656 153.754 146.026 1.00 35.52  ? 577 TYR A CA  1 
ATOM 856  C C   . TYR A 1 561 ? 142.013 153.146 147.263 1.00 31.59  ? 577 TYR A C   1 
ATOM 857  O O   . TYR A 1 561 ? 141.049 153.683 147.815 1.00 32.99  ? 577 TYR A O   1 
ATOM 858  C CB  . TYR A 1 561 ? 143.908 154.550 146.413 1.00 39.68  ? 577 TYR A CB  1 
ATOM 859  C CG  . TYR A 1 561 ? 143.640 155.722 147.329 1.00 40.50  ? 577 TYR A CG  1 
ATOM 860  C CD1 . TYR A 1 561 ? 143.661 155.568 148.708 1.00 41.12  ? 577 TYR A CD1 1 
ATOM 861  C CD2 . TYR A 1 561 ? 143.374 156.983 146.814 1.00 41.31  ? 577 TYR A CD2 1 
ATOM 862  C CE1 . TYR A 1 561 ? 143.420 156.636 149.549 1.00 45.28  ? 577 TYR A CE1 1 
ATOM 863  C CE2 . TYR A 1 561 ? 143.131 158.057 147.648 1.00 44.22  ? 577 TYR A CE2 1 
ATOM 864  C CZ  . TYR A 1 561 ? 143.156 157.877 149.014 1.00 44.70  ? 577 TYR A CZ  1 
ATOM 865  O OH  . TYR A 1 561 ? 142.915 158.943 149.848 1.00 44.93  ? 577 TYR A OH  1 
ATOM 866  N N   . PHE A 1 562 ? 142.561 152.010 147.689 1.00 26.07  ? 578 PHE A N   1 
ATOM 867  C CA  . PHE A 1 562 ? 142.090 151.288 148.861 1.00 27.30  ? 578 PHE A CA  1 
ATOM 868  C C   . PHE A 1 562 ? 143.233 151.135 149.852 1.00 27.74  ? 578 PHE A C   1 
ATOM 869  O O   . PHE A 1 562 ? 144.373 150.865 149.459 1.00 31.69  ? 578 PHE A O   1 
ATOM 870  C CB  . PHE A 1 562 ? 141.540 149.911 148.477 1.00 24.15  ? 578 PHE A CB  1 
ATOM 871  C CG  . PHE A 1 562 ? 140.386 149.966 147.518 1.00 20.08  ? 578 PHE A CG  1 
ATOM 872  C CD1 . PHE A 1 562 ? 139.082 149.971 147.983 1.00 20.73  ? 578 PHE A CD1 1 
ATOM 873  C CD2 . PHE A 1 562 ? 140.604 150.011 146.153 1.00 15.76  ? 578 PHE A CD2 1 
ATOM 874  C CE1 . PHE A 1 562 ? 138.019 150.021 147.103 1.00 25.06  ? 578 PHE A CE1 1 
ATOM 875  C CE2 . PHE A 1 562 ? 139.545 150.061 145.268 1.00 19.61  ? 578 PHE A CE2 1 
ATOM 876  C CZ  . PHE A 1 562 ? 138.251 150.067 145.745 1.00 29.21  ? 578 PHE A CZ  1 
ATOM 877  N N   . GLU A 1 563 ? 142.926 151.309 151.136 1.00 29.72  ? 579 GLU A N   1 
ATOM 878  C CA  . GLU A 1 563 ? 143.916 151.234 152.202 1.00 29.21  ? 579 GLU A CA  1 
ATOM 879  C C   . GLU A 1 563 ? 143.496 150.181 153.216 1.00 24.82  ? 579 GLU A C   1 
ATOM 880  O O   . GLU A 1 563 ? 142.315 150.084 153.564 1.00 43.15  ? 579 GLU A O   1 
ATOM 881  C CB  . GLU A 1 563 ? 144.086 152.589 152.894 1.00 37.22  ? 579 GLU A CB  1 
ATOM 882  C CG  . GLU A 1 563 ? 144.671 153.669 152.003 1.00 39.00  ? 579 GLU A CG  1 
ATOM 883  C CD  . GLU A 1 563 ? 144.891 154.974 152.742 1.00 46.95  ? 579 GLU A CD  1 
ATOM 884  O OE1 . GLU A 1 563 ? 144.536 155.048 153.937 1.00 49.51  ? 579 GLU A OE1 1 
ATOM 885  O OE2 . GLU A 1 563 ? 145.421 155.924 152.129 1.00 47.70  ? 579 GLU A OE2 1 
ATOM 886  N N   . PHE A 1 564 ? 144.465 149.400 153.687 1.00 15.52  ? 580 PHE A N   1 
ATOM 887  C CA  . PHE A 1 564 ? 144.215 148.378 154.697 1.00 17.49  ? 580 PHE A CA  1 
ATOM 888  C C   . PHE A 1 564 ? 144.407 148.995 156.077 1.00 20.74  ? 580 PHE A C   1 
ATOM 889  O O   . PHE A 1 564 ? 145.518 149.400 156.434 1.00 42.32  ? 580 PHE A O   1 
ATOM 890  C CB  . PHE A 1 564 ? 145.156 147.193 154.486 1.00 34.80  ? 580 PHE A CB  1 
ATOM 891  C CG  . PHE A 1 564 ? 144.690 145.914 155.131 1.00 31.91  ? 580 PHE A CG  1 
ATOM 892  C CD1 . PHE A 1 564 ? 144.264 145.890 156.448 1.00 30.00  ? 580 PHE A CD1 1 
ATOM 893  C CD2 . PHE A 1 564 ? 144.678 144.733 154.410 1.00 24.77  ? 580 PHE A CD2 1 
ATOM 894  C CE1 . PHE A 1 564 ? 143.839 144.712 157.032 1.00 27.94  ? 580 PHE A CE1 1 
ATOM 895  C CE2 . PHE A 1 564 ? 144.254 143.554 154.989 1.00 33.45  ? 580 PHE A CE2 1 
ATOM 896  C CZ  . PHE A 1 564 ? 143.835 143.544 156.300 1.00 34.81  ? 580 PHE A CZ  1 
ATOM 897  N N   . GLU A 1 565 ? 143.330 149.059 156.855 1.00 19.41  ? 581 GLU A N   1 
ATOM 898  C CA  . GLU A 1 565 ? 143.337 149.691 158.167 1.00 31.03  ? 581 GLU A CA  1 
ATOM 899  C C   . GLU A 1 565 ? 143.279 148.621 159.248 1.00 26.34  ? 581 GLU A C   1 
ATOM 900  O O   . GLU A 1 565 ? 142.521 147.652 159.129 1.00 36.59  ? 581 GLU A O   1 
ATOM 901  C CB  . GLU A 1 565 ? 142.157 150.656 158.308 1.00 37.42  ? 581 GLU A CB  1 
ATOM 902  C CG  . GLU A 1 565 ? 142.251 151.580 159.509 1.00 42.18  ? 581 GLU A CG  1 
ATOM 903  C CD  . GLU A 1 565 ? 141.079 152.537 159.596 1.00 46.41  ? 581 GLU A CD  1 
ATOM 904  O OE1 . GLU A 1 565 ? 139.960 152.144 159.206 1.00 49.55  ? 581 GLU A OE1 1 
ATOM 905  O OE2 . GLU A 1 565 ? 141.276 153.685 160.045 1.00 42.71  ? 581 GLU A OE2 1 
ATOM 906  N N   . ALA A 1 566 ? 144.082 148.797 160.296 1.00 39.73  ? 582 ALA A N   1 
ATOM 907  C CA  . ALA A 1 566 ? 144.161 147.852 161.399 1.00 37.15  ? 582 ALA A CA  1 
ATOM 908  C C   . ALA A 1 566 ? 143.953 148.574 162.723 1.00 44.12  ? 582 ALA A C   1 
ATOM 909  O O   . ALA A 1 566 ? 144.278 149.757 162.864 1.00 53.31  ? 582 ALA A O   1 
ATOM 910  C CB  . ALA A 1 566 ? 145.511 147.127 161.413 1.00 43.11  ? 582 ALA A CB  1 
ATOM 911  N N   . PHE A 1 567 ? 143.409 147.846 163.696 1.00 51.26  ? 583 PHE A N   1 
ATOM 912  C CA  . PHE A 1 567 ? 143.145 148.391 165.019 1.00 53.40  ? 583 PHE A CA  1 
ATOM 913  C C   . PHE A 1 567 ? 143.218 147.263 166.038 1.00 52.67  ? 583 PHE A C   1 
ATOM 914  O O   . PHE A 1 567 ? 142.731 146.156 165.794 1.00 58.15  ? 583 PHE A O   1 
ATOM 915  C CB  . PHE A 1 567 ? 141.774 149.081 165.071 1.00 53.36  ? 583 PHE A CB  1 
ATOM 916  C CG  . PHE A 1 567 ? 141.420 149.645 166.418 1.00 55.07  ? 583 PHE A CG  1 
ATOM 917  C CD1 . PHE A 1 567 ? 140.815 148.853 167.380 1.00 57.42  ? 583 PHE A CD1 1 
ATOM 918  C CD2 . PHE A 1 567 ? 141.672 150.972 166.715 1.00 59.04  ? 583 PHE A CD2 1 
ATOM 919  C CE1 . PHE A 1 567 ? 140.481 149.370 168.616 1.00 57.11  ? 583 PHE A CE1 1 
ATOM 920  C CE2 . PHE A 1 567 ? 141.339 151.496 167.949 1.00 59.80  ? 583 PHE A CE2 1 
ATOM 921  C CZ  . PHE A 1 567 ? 140.743 150.694 168.900 1.00 58.15  ? 583 PHE A CZ  1 
ATOM 922  N N   . GLN A 1 568 ? 143.834 147.555 167.182 1.00 61.98  ? 584 GLN A N   1 
ATOM 923  C CA  . GLN A 1 568 ? 143.970 146.577 168.252 1.00 61.27  ? 584 GLN A CA  1 
ATOM 924  C C   . GLN A 1 568 ? 143.706 147.263 169.584 1.00 63.37  ? 584 GLN A C   1 
ATOM 925  O O   . GLN A 1 568 ? 143.904 148.473 169.725 1.00 67.60  ? 584 GLN A O   1 
ATOM 926  C CB  . GLN A 1 568 ? 145.358 145.924 168.243 1.00 59.23  ? 584 GLN A CB  1 
ATOM 927  C CG  . GLN A 1 568 ? 146.511 146.882 168.501 1.00 62.07  ? 584 GLN A CG  1 
ATOM 928  C CD  . GLN A 1 568 ? 146.929 146.921 169.958 1.00 68.77  ? 584 GLN A CD  1 
ATOM 929  O OE1 . GLN A 1 568 ? 146.177 146.519 170.845 1.00 65.14  ? 584 GLN A OE1 1 
ATOM 930  N NE2 . GLN A 1 568 ? 148.141 147.401 170.210 1.00 72.23  ? 584 GLN A NE2 1 
ATOM 931  N N   . ASP A 1 569 ? 143.255 146.474 170.561 1.00 66.63  ? 585 ASP A N   1 
ATOM 932  C CA  . ASP A 1 569 ? 142.877 146.986 171.874 1.00 66.99  ? 585 ASP A CA  1 
ATOM 933  C C   . ASP A 1 569 ? 143.573 146.211 172.988 1.00 63.78  ? 585 ASP A C   1 
ATOM 934  O O   . ASP A 1 569 ? 143.032 146.071 174.087 1.00 67.65  ? 585 ASP A O   1 
ATOM 935  C CB  . ASP A 1 569 ? 141.360 146.938 172.055 1.00 63.44  ? 585 ASP A CB  1 
ATOM 936  C CG  . ASP A 1 569 ? 140.888 147.732 173.260 1.00 65.36  ? 585 ASP A CG  1 
ATOM 937  O OD1 . ASP A 1 569 ? 141.737 148.341 173.944 1.00 72.80  ? 585 ASP A OD1 1 
ATOM 938  O OD2 . ASP A 1 569 ? 139.667 147.745 173.521 1.00 60.24  ? 585 ASP A OD2 1 
ATOM 939  N N   . SER A 1 570 ? 144.770 145.697 172.718 1.00 57.44  ? 586 SER A N   1 
ATOM 940  C CA  . SER A 1 570 ? 145.532 144.975 173.723 1.00 64.12  ? 586 SER A CA  1 
ATOM 941  C C   . SER A 1 570 ? 146.523 145.909 174.413 1.00 68.77  ? 586 SER A C   1 
ATOM 942  O O   . SER A 1 570 ? 146.899 146.961 173.890 1.00 69.55  ? 586 SER A O   1 
ATOM 943  C CB  . SER A 1 570 ? 146.272 143.799 173.089 1.00 65.62  ? 586 SER A CB  1 
ATOM 944  O OG  . SER A 1 570 ? 147.254 144.252 172.174 1.00 68.32  ? 586 SER A OG  1 
ATOM 945  N N   . GLU A 1 571 ? 146.950 145.509 175.608 1.00 70.75  ? 587 GLU A N   1 
ATOM 946  C CA  . GLU A 1 571 ? 147.918 146.300 176.354 1.00 68.53  ? 587 GLU A CA  1 
ATOM 947  C C   . GLU A 1 571 ? 149.233 146.366 175.586 1.00 72.20  ? 587 GLU A C   1 
ATOM 948  O O   . GLU A 1 571 ? 149.727 145.349 175.090 1.00 76.04  ? 587 GLU A O   1 
ATOM 949  C CB  . GLU A 1 571 ? 148.137 145.708 177.748 1.00 71.18  ? 587 GLU A CB  1 
ATOM 950  C CG  . GLU A 1 571 ? 148.997 144.443 177.803 1.00 73.37  ? 587 GLU A CG  1 
ATOM 951  C CD  . GLU A 1 571 ? 148.386 143.272 177.059 1.00 73.60  ? 587 GLU A CD  1 
ATOM 952  O OE1 . GLU A 1 571 ? 147.213 143.375 176.643 1.00 72.59  ? 587 GLU A OE1 1 
ATOM 953  O OE2 . GLU A 1 571 ? 149.079 142.247 176.893 1.00 74.97  ? 587 GLU A OE2 1 
ATOM 954  N N   . GLY A 1 572 ? 149.794 147.566 175.482 1.00 71.70  ? 588 GLY A N   1 
ATOM 955  C CA  . GLY A 1 572 ? 151.037 147.741 174.765 1.00 71.77  ? 588 GLY A CA  1 
ATOM 956  C C   . GLY A 1 572 ? 150.839 147.679 173.258 1.00 68.55  ? 588 GLY A C   1 
ATOM 957  O O   . GLY A 1 572 ? 149.725 147.598 172.739 1.00 60.36  ? 588 GLY A O   1 
ATOM 958  N N   . ASP A 1 573 ? 151.966 147.719 172.555 1.00 74.13  ? 589 ASP A N   1 
ATOM 959  C CA  . ASP A 1 573 ? 151.943 147.659 171.101 1.00 68.43  ? 589 ASP A CA  1 
ATOM 960  C C   . ASP A 1 573 ? 151.799 146.219 170.624 1.00 67.91  ? 589 ASP A C   1 
ATOM 961  O O   . ASP A 1 573 ? 152.090 145.265 171.350 1.00 68.62  ? 589 ASP A O   1 
ATOM 962  C CB  . ASP A 1 573 ? 153.215 148.274 170.520 1.00 69.48  ? 589 ASP A CB  1 
ATOM 963  C CG  . ASP A 1 573 ? 153.360 149.743 170.862 1.00 69.70  ? 589 ASP A CG  1 
ATOM 964  O OD1 . ASP A 1 573 ? 152.478 150.282 171.563 1.00 69.19  ? 589 ASP A OD1 1 
ATOM 965  O OD2 . ASP A 1 573 ? 154.357 150.360 170.431 1.00 70.44  ? 589 ASP A OD2 1 
ATOM 966  N N   . ARG A 1 574 ? 151.345 146.071 169.383 1.00 61.99  ? 590 ARG A N   1 
ATOM 967  C CA  . ARG A 1 574 ? 151.185 144.773 168.748 1.00 65.16  ? 590 ARG A CA  1 
ATOM 968  C C   . ARG A 1 574 ? 151.935 144.755 167.425 1.00 63.89  ? 590 ARG A C   1 
ATOM 969  O O   . ARG A 1 574 ? 152.091 145.787 166.765 1.00 61.32  ? 590 ARG A O   1 
ATOM 970  C CB  . ARG A 1 574 ? 149.705 144.444 168.513 1.00 62.89  ? 590 ARG A CB  1 
ATOM 971  C CG  . ARG A 1 574 ? 148.918 144.148 169.783 1.00 62.31  ? 590 ARG A CG  1 
ATOM 972  C CD  . ARG A 1 574 ? 149.054 142.692 170.214 1.00 60.36  ? 590 ARG A CD  1 
ATOM 973  N NE  . ARG A 1 574 ? 150.398 142.368 170.678 1.00 66.46  ? 590 ARG A NE  1 
ATOM 974  C CZ  . ARG A 1 574 ? 150.817 142.504 171.930 1.00 68.71  ? 590 ARG A CZ  1 
ATOM 975  N NH1 . ARG A 1 574 ? 150.023 142.970 172.880 1.00 62.25  ? 590 ARG A NH1 1 
ATOM 976  N NH2 . ARG A 1 574 ? 152.065 142.164 172.235 1.00 72.13  ? 590 ARG A NH2 1 
ATOM 977  N N   . GLN A 1 575 ? 152.397 143.568 167.043 1.00 63.88  ? 591 GLN A N   1 
ATOM 978  C CA  . GLN A 1 575 ? 153.207 143.401 165.845 1.00 64.94  ? 591 GLN A CA  1 
ATOM 979  C C   . GLN A 1 575 ? 152.342 142.902 164.696 1.00 63.36  ? 591 GLN A C   1 
ATOM 980  O O   . GLN A 1 575 ? 151.722 141.838 164.791 1.00 58.61  ? 591 GLN A O   1 
ATOM 981  C CB  . GLN A 1 575 ? 154.352 142.422 166.106 1.00 61.14  ? 591 GLN A CB  1 
ATOM 982  C CG  . GLN A 1 575 ? 155.232 142.799 167.289 1.00 64.34  ? 591 GLN A CG  1 
ATOM 983  C CD  . GLN A 1 575 ? 155.866 144.169 167.140 1.00 67.81  ? 591 GLN A CD  1 
ATOM 984  O OE1 . GLN A 1 575 ? 155.922 144.944 168.095 1.00 69.19  ? 591 GLN A OE1 1 
ATOM 985  N NE2 . GLN A 1 575 ? 156.354 144.472 165.942 1.00 62.92  ? 591 GLN A NE2 1 
ATOM 986  N N   . PHE A 1 576 ? 152.303 143.674 163.614 1.00 47.38  ? 592 PHE A N   1 
ATOM 987  C CA  . PHE A 1 576 ? 151.629 143.274 162.382 1.00 36.76  ? 592 PHE A CA  1 
ATOM 988  C C   . PHE A 1 576 ? 152.621 142.425 161.598 1.00 40.16  ? 592 PHE A C   1 
ATOM 989  O O   . PHE A 1 576 ? 153.356 142.930 160.746 1.00 48.37  ? 592 PHE A O   1 
ATOM 990  C CB  . PHE A 1 576 ? 151.172 144.497 161.595 1.00 41.82  ? 592 PHE A CB  1 
ATOM 991  C CG  . PHE A 1 576 ? 150.063 144.216 160.623 1.00 35.32  ? 592 PHE A CG  1 
ATOM 992  C CD1 . PHE A 1 576 ? 150.341 143.770 159.344 1.00 35.36  ? 592 PHE A CD1 1 
ATOM 993  C CD2 . PHE A 1 576 ? 148.742 144.408 160.987 1.00 34.92  ? 592 PHE A CD2 1 
ATOM 994  C CE1 . PHE A 1 576 ? 149.322 143.516 158.447 1.00 42.25  ? 592 PHE A CE1 1 
ATOM 995  C CE2 . PHE A 1 576 ? 147.720 144.156 160.095 1.00 41.22  ? 592 PHE A CE2 1 
ATOM 996  C CZ  . PHE A 1 576 ? 148.010 143.708 158.824 1.00 47.43  ? 592 PHE A CZ  1 
ATOM 997  N N   . ARG A 1 577 ? 152.640 141.128 161.892 1.00 40.74  ? 593 ARG A N   1 
ATOM 998  C CA  . ARG A 1 577 ? 153.693 140.249 161.407 1.00 44.61  ? 593 ARG A CA  1 
ATOM 999  C C   . ARG A 1 577 ? 153.702 140.180 159.887 1.00 42.89  ? 593 ARG A C   1 
ATOM 1000 O O   . ARG A 1 577 ? 152.650 140.158 159.241 1.00 51.04  ? 593 ARG A O   1 
ATOM 1001 C CB  . ARG A 1 577 ? 153.515 138.844 161.982 1.00 46.28  ? 593 ARG A CB  1 
ATOM 1002 C CG  . ARG A 1 577 ? 153.548 138.781 163.499 1.00 53.15  ? 593 ARG A CG  1 
ATOM 1003 C CD  . ARG A 1 577 ? 153.350 137.360 163.995 1.00 47.05  ? 593 ARG A CD  1 
ATOM 1004 N NE  . ARG A 1 577 ? 154.383 136.461 163.497 1.00 47.27  ? 593 ARG A NE  1 
ATOM 1005 C CZ  . ARG A 1 577 ? 154.405 135.152 163.710 1.00 51.92  ? 593 ARG A CZ  1 
ATOM 1006 N NH1 . ARG A 1 577 ? 153.459 134.549 164.411 1.00 51.52  ? 593 ARG A NH1 1 
ATOM 1007 N NH2 . ARG A 1 577 ? 155.401 134.430 163.205 1.00 53.76  ? 593 ARG A NH2 1 
ATOM 1008 N N   . ALA A 1 578 ? 154.905 140.150 159.319 1.00 42.35  ? 594 ALA A N   1 
ATOM 1009 C CA  . ALA A 1 578 ? 155.087 139.911 157.890 1.00 51.53  ? 594 ALA A CA  1 
ATOM 1010 C C   . ALA A 1 578 ? 155.157 138.407 157.666 1.00 51.17  ? 594 ALA A C   1 
ATOM 1011 O O   . ALA A 1 578 ? 156.214 137.791 157.811 1.00 52.71  ? 594 ALA A O   1 
ATOM 1012 C CB  . ALA A 1 578 ? 156.347 140.605 157.387 1.00 46.28  ? 594 ALA A CB  1 
ATOM 1013 N N   . ASP A 1 579 ? 154.024 137.812 157.306 1.00 43.91  ? 595 ASP A N   1 
ATOM 1014 C CA  . ASP A 1 579 ? 153.900 136.365 157.208 1.00 43.33  ? 595 ASP A CA  1 
ATOM 1015 C C   . ASP A 1 579 ? 153.133 136.040 155.936 1.00 43.53  ? 595 ASP A C   1 
ATOM 1016 O O   . ASP A 1 579 ? 152.312 136.848 155.485 1.00 44.98  ? 595 ASP A O   1 
ATOM 1017 C CB  . ASP A 1 579 ? 153.181 135.795 158.443 1.00 46.34  ? 595 ASP A CB  1 
ATOM 1018 C CG  . ASP A 1 579 ? 152.998 134.292 158.382 1.00 55.81  ? 595 ASP A CG  1 
ATOM 1019 O OD1 . ASP A 1 579 ? 152.260 133.810 157.497 1.00 60.59  ? 595 ASP A OD1 1 
ATOM 1020 O OD2 . ASP A 1 579 ? 153.595 133.588 159.224 1.00 52.90  ? 595 ASP A OD2 1 
ATOM 1021 N N   . PRO A 1 580 ? 153.379 134.875 155.328 1.00 45.79  ? 596 PRO A N   1 
ATOM 1022 C CA  . PRO A 1 580 ? 152.589 134.495 154.146 1.00 42.71  ? 596 PRO A CA  1 
ATOM 1023 C C   . PRO A 1 580 ? 151.088 134.603 154.354 1.00 38.64  ? 596 PRO A C   1 
ATOM 1024 O O   . PRO A 1 580 ? 150.344 134.734 153.373 1.00 39.84  ? 596 PRO A O   1 
ATOM 1025 C CB  . PRO A 1 580 ? 153.026 133.048 153.896 1.00 41.84  ? 596 PRO A CB  1 
ATOM 1026 C CG  . PRO A 1 580 ? 154.427 133.005 154.377 1.00 44.12  ? 596 PRO A CG  1 
ATOM 1027 C CD  . PRO A 1 580 ? 154.509 133.952 155.548 1.00 45.68  ? 596 PRO A CD  1 
ATOM 1028 N N   . TYR A 1 581 ? 150.616 134.549 155.599 1.00 32.35  ? 597 TYR A N   1 
ATOM 1029 C CA  . TYR A 1 581 ? 149.206 134.739 155.907 1.00 21.71  ? 597 TYR A CA  1 
ATOM 1030 C C   . TYR A 1 581 ? 148.860 136.199 156.183 1.00 29.88  ? 597 TYR A C   1 
ATOM 1031 O O   . TYR A 1 581 ? 147.827 136.476 156.802 1.00 44.37  ? 597 TYR A O   1 
ATOM 1032 C CB  . TYR A 1 581 ? 148.809 133.870 157.101 1.00 28.55  ? 597 TYR A CB  1 
ATOM 1033 C CG  . TYR A 1 581 ? 148.937 132.389 156.831 1.00 28.45  ? 597 TYR A CG  1 
ATOM 1034 C CD1 . TYR A 1 581 ? 148.073 131.748 155.954 1.00 25.45  ? 597 TYR A CD1 1 
ATOM 1035 C CD2 . TYR A 1 581 ? 149.920 131.633 157.452 1.00 31.99  ? 597 TYR A CD2 1 
ATOM 1036 C CE1 . TYR A 1 581 ? 148.185 130.397 155.703 1.00 29.39  ? 597 TYR A CE1 1 
ATOM 1037 C CE2 . TYR A 1 581 ? 150.040 130.280 157.207 1.00 37.95  ? 597 TYR A CE2 1 
ATOM 1038 C CZ  . TYR A 1 581 ? 149.169 129.668 156.332 1.00 36.53  ? 597 TYR A CZ  1 
ATOM 1039 O OH  . TYR A 1 581 ? 149.284 128.321 156.085 1.00 44.90  ? 597 TYR A OH  1 
ATOM 1040 N N   . THR A 1 582 ? 149.700 137.132 155.739 1.00 27.51  ? 598 THR A N   1 
ATOM 1041 C CA  . THR A 1 582 ? 149.447 138.565 155.860 1.00 25.17  ? 598 THR A CA  1 
ATOM 1042 C C   . THR A 1 582 ? 149.642 139.176 154.478 1.00 20.33  ? 598 THR A C   1 
ATOM 1043 O O   . THR A 1 582 ? 150.779 139.344 154.025 1.00 32.29  ? 598 THR A O   1 
ATOM 1044 C CB  . THR A 1 582 ? 150.377 139.210 156.886 1.00 34.41  ? 598 THR A CB  1 
ATOM 1045 O OG1 . THR A 1 582 ? 150.168 138.611 158.171 1.00 37.66  ? 598 THR A OG1 1 
ATOM 1046 C CG2 . THR A 1 582 ? 150.121 140.706 156.981 1.00 35.88  ? 598 THR A CG2 1 
ATOM 1047 N N   . TRP A 1 583 ? 148.539 139.508 153.813 1.00 11.81  ? 599 TRP A N   1 
ATOM 1048 C CA  . TRP A 1 583 ? 148.600 139.960 152.432 1.00 20.53  ? 599 TRP A CA  1 
ATOM 1049 C C   . TRP A 1 583 ? 147.435 140.897 152.158 1.00 18.21  ? 599 TRP A C   1 
ATOM 1050 O O   . TRP A 1 583 ? 146.436 140.909 152.882 1.00 22.43  ? 599 TRP A O   1 
ATOM 1051 C CB  . TRP A 1 583 ? 148.575 138.775 151.461 1.00 24.03  ? 599 TRP A CB  1 
ATOM 1052 C CG  . TRP A 1 583 ? 147.511 137.773 151.786 1.00 22.06  ? 599 TRP A CG  1 
ATOM 1053 C CD1 . TRP A 1 583 ? 147.625 136.699 152.619 1.00 22.47  ? 599 TRP A CD1 1 
ATOM 1054 C CD2 . TRP A 1 583 ? 146.167 137.755 151.290 1.00 25.08  ? 599 TRP A CD2 1 
ATOM 1055 N NE1 . TRP A 1 583 ? 146.438 136.011 152.670 1.00 29.32  ? 599 TRP A NE1 1 
ATOM 1056 C CE2 . TRP A 1 583 ? 145.527 136.639 151.863 1.00 20.75  ? 599 TRP A CE2 1 
ATOM 1057 C CE3 . TRP A 1 583 ? 145.444 138.572 150.416 1.00 23.60  ? 599 TRP A CE3 1 
ATOM 1058 C CZ2 . TRP A 1 583 ? 144.200 136.319 151.592 1.00 16.26  ? 599 TRP A CZ2 1 
ATOM 1059 C CZ3 . TRP A 1 583 ? 144.125 138.251 150.147 1.00 23.82  ? 599 TRP A CZ3 1 
ATOM 1060 C CH2 . TRP A 1 583 ? 143.518 137.135 150.734 1.00 23.61  ? 599 TRP A CH2 1 
ATOM 1061 N N   . PHE A 1 584 ? 147.585 141.685 151.097 1.00 17.51  ? 600 PHE A N   1 
ATOM 1062 C CA  . PHE A 1 584 ? 146.558 142.611 150.646 1.00 17.68  ? 600 PHE A CA  1 
ATOM 1063 C C   . PHE A 1 584 ? 146.431 142.477 149.137 1.00 10.24  ? 600 PHE A C   1 
ATOM 1064 O O   . PHE A 1 584 ? 147.419 142.626 148.412 1.00 25.88  ? 600 PHE A O   1 
ATOM 1065 C CB  . PHE A 1 584 ? 146.912 144.054 151.032 1.00 22.45  ? 600 PHE A CB  1 
ATOM 1066 C CG  . PHE A 1 584 ? 145.796 145.047 150.827 1.00 14.51  ? 600 PHE A CG  1 
ATOM 1067 C CD1 . PHE A 1 584 ? 144.481 144.638 150.688 1.00 18.03  ? 600 PHE A CD1 1 
ATOM 1068 C CD2 . PHE A 1 584 ? 146.076 146.402 150.776 1.00 22.13  ? 600 PHE A CD2 1 
ATOM 1069 C CE1 . PHE A 1 584 ? 143.471 145.561 150.505 1.00 23.61  ? 600 PHE A CE1 1 
ATOM 1070 C CE2 . PHE A 1 584 ? 145.069 147.327 150.592 1.00 24.32  ? 600 PHE A CE2 1 
ATOM 1071 C CZ  . PHE A 1 584 ? 143.766 146.906 150.456 1.00 25.67  ? 600 PHE A CZ  1 
ATOM 1072 N N   . SER A 1 585 ? 145.218 142.194 148.667 1.00 13.89  ? 601 SER A N   1 
ATOM 1073 C CA  . SER A 1 585 ? 145.009 141.877 147.263 1.00 16.41  ? 601 SER A CA  1 
ATOM 1074 C C   . SER A 1 585 ? 143.834 142.674 146.718 1.00 17.32  ? 601 SER A C   1 
ATOM 1075 O O   . SER A 1 585 ? 142.881 142.981 147.439 1.00 37.62  ? 601 SER A O   1 
ATOM 1076 C CB  . SER A 1 585 ? 144.758 140.378 147.063 1.00 32.53  ? 601 SER A CB  1 
ATOM 1077 O OG  . SER A 1 585 ? 144.495 140.081 145.703 1.00 40.60  ? 601 SER A OG  1 
ATOM 1078 N N   . ILE A 1 586 ? 143.921 143.005 145.432 1.00 15.27  ? 602 ILE A N   1 
ATOM 1079 C CA  . ILE A 1 586 ? 142.842 143.655 144.699 1.00 16.91  ? 602 ILE A CA  1 
ATOM 1080 C C   . ILE A 1 586 ? 142.728 142.982 143.339 1.00 17.07  ? 602 ILE A C   1 
ATOM 1081 O O   . ILE A 1 586 ? 143.740 142.682 142.698 1.00 23.57  ? 602 ILE A O   1 
ATOM 1082 C CB  . ILE A 1 586 ? 143.084 145.172 144.544 1.00 12.86  ? 602 ILE A CB  1 
ATOM 1083 C CG1 . ILE A 1 586 ? 141.863 145.838 143.908 1.00 28.54  ? 602 ILE A CG1 1 
ATOM 1084 C CG2 . ILE A 1 586 ? 144.326 145.435 143.705 1.00 19.15  ? 602 ILE A CG2 1 
ATOM 1085 C CD1 . ILE A 1 586 ? 141.976 147.339 143.799 1.00 33.07  ? 602 ILE A CD1 1 
ATOM 1086 N N   . GLU A 1 587 ? 141.493 142.744 142.900 1.00 17.17  ? 603 GLU A N   1 
ATOM 1087 C CA  . GLU A 1 587 ? 141.226 142.048 141.649 1.00 20.32  ? 603 GLU A CA  1 
ATOM 1088 C C   . GLU A 1 587 ? 140.302 142.895 140.789 1.00 17.82  ? 603 GLU A C   1 
ATOM 1089 O O   . GLU A 1 587 ? 139.439 143.606 141.313 1.00 34.92  ? 603 GLU A O   1 
ATOM 1090 C CB  . GLU A 1 587 ? 140.598 140.674 141.901 1.00 24.71  ? 603 GLU A CB  1 
ATOM 1091 C CG  . GLU A 1 587 ? 140.309 139.883 140.634 1.00 25.58  ? 603 GLU A CG  1 
ATOM 1092 C CD  . GLU A 1 587 ? 139.714 138.519 140.922 1.00 39.06  ? 603 GLU A CD  1 
ATOM 1093 O OE1 . GLU A 1 587 ? 139.518 138.194 142.113 1.00 40.40  ? 603 GLU A OE1 1 
ATOM 1094 O OE2 . GLU A 1 587 ? 139.440 137.773 139.959 1.00 38.61  ? 603 GLU A OE2 1 
ATOM 1095 N N   . ALA A 1 588 ? 140.486 142.815 139.474 1.00 20.61  ? 604 ALA A N   1 
ATOM 1096 C CA  . ALA A 1 588 ? 139.662 143.547 138.522 1.00 14.69  ? 604 ALA A CA  1 
ATOM 1097 C C   . ALA A 1 588 ? 138.586 142.618 137.974 1.00 29.71  ? 604 ALA A C   1 
ATOM 1098 O O   . ALA A 1 588 ? 138.897 141.552 137.431 1.00 30.28  ? 604 ALA A O   1 
ATOM 1099 C CB  . ALA A 1 588 ? 140.517 144.109 137.388 1.00 18.28  ? 604 ALA A CB  1 
ATOM 1100 N N   . ILE A 1 589 ? 137.328 143.025 138.113 1.00 30.22  ? 605 ILE A N   1 
ATOM 1101 C CA  . ILE A 1 589 ? 136.208 142.202 137.667 1.00 15.21  ? 605 ILE A CA  1 
ATOM 1102 C C   . ILE A 1 589 ? 135.665 142.682 136.328 1.00 24.46  ? 605 ILE A C   1 
ATOM 1103 O O   . ILE A 1 589 ? 135.402 141.873 135.434 1.00 28.14  ? 605 ILE A O   1 
ATOM 1104 C CB  . ILE A 1 589 ? 135.107 142.191 138.746 1.00 22.10  ? 605 ILE A CB  1 
ATOM 1105 C CG1 . ILE A 1 589 ? 135.673 141.737 140.095 1.00 24.21  ? 605 ILE A CG1 1 
ATOM 1106 C CG2 . ILE A 1 589 ? 133.959 141.294 138.320 1.00 30.59  ? 605 ILE A CG2 1 
ATOM 1107 C CD1 . ILE A 1 589 ? 136.297 140.356 140.080 1.00 24.48  ? 605 ILE A CD1 1 
ATOM 1108 N N   . GLU A 1 590 ? 135.489 143.992 136.168 1.00 31.72  ? 606 GLU A N   1 
ATOM 1109 C CA  . GLU A 1 590 ? 134.927 144.571 134.957 1.00 31.03  ? 606 GLU A CA  1 
ATOM 1110 C C   . GLU A 1 590 ? 135.914 145.563 134.362 1.00 28.29  ? 606 GLU A C   1 
ATOM 1111 O O   . GLU A 1 590 ? 136.580 146.305 135.091 1.00 36.05  ? 606 GLU A O   1 
ATOM 1112 C CB  . GLU A 1 590 ? 133.592 145.268 135.243 1.00 37.38  ? 606 GLU A CB  1 
ATOM 1113 C CG  . GLU A 1 590 ? 132.903 145.823 134.008 1.00 40.36  ? 606 GLU A CG  1 
ATOM 1114 C CD  . GLU A 1 590 ? 131.559 146.449 134.322 1.00 42.13  ? 606 GLU A CD  1 
ATOM 1115 O OE1 . GLU A 1 590 ? 131.146 146.410 135.500 1.00 38.86  ? 606 GLU A OE1 1 
ATOM 1116 O OE2 . GLU A 1 590 ? 130.916 146.978 133.392 1.00 48.58  ? 606 GLU A OE2 1 
ATOM 1117 N N   . LEU A 1 591 ? 136.001 145.572 133.035 1.00 33.48  ? 607 LEU A N   1 
ATOM 1118 C CA  . LEU A 1 591 ? 136.909 146.443 132.306 1.00 37.39  ? 607 LEU A CA  1 
ATOM 1119 C C   . LEU A 1 591 ? 136.117 147.385 131.409 1.00 47.99  ? 607 LEU A C   1 
ATOM 1120 O O   . LEU A 1 591 ? 135.022 147.055 130.944 1.00 48.99  ? 607 LEU A O   1 
ATOM 1121 C CB  . LEU A 1 591 ? 137.894 145.631 131.459 1.00 36.37  ? 607 LEU A CB  1 
ATOM 1122 C CG  . LEU A 1 591 ? 138.699 144.566 132.205 1.00 39.84  ? 607 LEU A CG  1 
ATOM 1123 C CD1 . LEU A 1 591 ? 139.615 143.827 131.245 1.00 41.02  ? 607 LEU A CD1 1 
ATOM 1124 C CD2 . LEU A 1 591 ? 139.497 145.187 133.340 1.00 36.38  ? 607 LEU A CD2 1 
ATOM 1125 N N   . GLU A 1 592 ? 136.685 148.565 131.170 1.00 52.30  ? 608 GLU A N   1 
ATOM 1126 C CA  . GLU A 1 592 ? 136.021 149.560 130.341 1.00 56.62  ? 608 GLU A CA  1 
ATOM 1127 C C   . GLU A 1 592 ? 135.879 149.053 128.911 1.00 59.05  ? 608 GLU A C   1 
ATOM 1128 O O   . GLU A 1 592 ? 136.786 148.413 128.371 1.00 57.57  ? 608 GLU A O   1 
ATOM 1129 C CB  . GLU A 1 592 ? 136.807 150.871 130.362 1.00 60.42  ? 608 GLU A CB  1 
ATOM 1130 C CG  . GLU A 1 592 ? 136.161 151.994 129.567 1.00 60.39  ? 608 GLU A CG  1 
ATOM 1131 C CD  . GLU A 1 592 ? 136.959 153.282 129.620 1.00 59.69  ? 608 GLU A CD  1 
ATOM 1132 O OE1 . GLU A 1 592 ? 138.026 153.295 130.270 1.00 56.98  ? 608 GLU A OE1 1 
ATOM 1133 O OE2 . GLU A 1 592 ? 136.521 154.281 129.012 1.00 63.27  ? 608 GLU A OE2 1 
ATOM 1134 N N   . THR A 1 593 ? 134.732 149.344 128.301 1.00 67.42  ? 609 THR A N   1 
ATOM 1135 C CA  . THR A 1 593 ? 134.455 148.954 126.927 1.00 70.01  ? 609 THR A CA  1 
ATOM 1136 C C   . THR A 1 593 ? 133.574 150.014 126.283 1.00 74.15  ? 609 THR A C   1 
ATOM 1137 O O   . THR A 1 593 ? 132.968 150.844 126.965 1.00 75.73  ? 609 THR A O   1 
ATOM 1138 C CB  . THR A 1 593 ? 133.769 147.582 126.846 1.00 73.96  ? 609 THR A CB  1 
ATOM 1139 O OG1 . THR A 1 593 ? 132.571 147.594 127.631 1.00 70.52  ? 609 THR A OG1 1 
ATOM 1140 C CG2 . THR A 1 593 ? 134.696 146.484 127.351 1.00 72.65  ? 609 THR A CG2 1 
ATOM 1141 N N   . GLU A 1 594 ? 133.516 149.983 124.954 1.00 84.28  ? 610 GLU A N   1 
ATOM 1142 C CA  . GLU A 1 594 ? 132.693 150.937 124.221 1.00 84.52  ? 610 GLU A CA  1 
ATOM 1143 C C   . GLU A 1 594 ? 131.249 150.848 124.694 1.00 86.06  ? 610 GLU A C   1 
ATOM 1144 O O   . GLU A 1 594 ? 130.671 149.759 124.755 1.00 87.49  ? 610 GLU A O   1 
ATOM 1145 C CB  . GLU A 1 594 ? 132.785 150.666 122.720 1.00 84.54  ? 610 GLU A CB  1 
ATOM 1146 C CG  . GLU A 1 594 ? 134.174 150.867 122.140 1.00 88.27  ? 610 GLU A CG  1 
ATOM 1147 C CD  . GLU A 1 594 ? 134.231 150.579 120.653 1.00 88.24  ? 610 GLU A CD  1 
ATOM 1148 O OE1 . GLU A 1 594 ? 133.202 150.152 120.088 1.00 89.58  ? 610 GLU A OE1 1 
ATOM 1149 O OE2 . GLU A 1 594 ? 135.305 150.781 120.047 1.00 86.95  ? 610 GLU A OE2 1 
ATOM 1150 N N   . THR A 1 595 ? 130.667 152.000 125.025 1.00 83.08  ? 611 THR A N   1 
ATOM 1151 C CA  . THR A 1 595 ? 129.321 152.064 125.579 1.00 81.53  ? 611 THR A CA  1 
ATOM 1152 C C   . THR A 1 595 ? 128.291 152.607 124.598 1.00 77.01  ? 611 THR A C   1 
ATOM 1153 O O   . THR A 1 595 ? 127.120 152.736 124.968 1.00 75.81  ? 611 THR A O   1 
ATOM 1154 C CB  . THR A 1 595 ? 129.312 152.934 126.842 1.00 80.22  ? 611 THR A CB  1 
ATOM 1155 O OG1 . THR A 1 595 ? 129.664 154.281 126.502 1.00 80.31  ? 611 THR A OG1 1 
ATOM 1156 C CG2 . THR A 1 595 ? 130.298 152.401 127.870 1.00 80.73  ? 611 THR A CG2 1 
ATOM 1157 N N   . MET A 1 596 ? 128.690 152.927 123.367 1.00 75.59  ? 612 MET A N   1 
ATOM 1158 C CA  . MET A 1 596 ? 127.825 153.528 122.357 1.00 75.88  ? 612 MET A CA  1 
ATOM 1159 C C   . MET A 1 596 ? 127.413 154.947 122.725 1.00 77.08  ? 612 MET A C   1 
ATOM 1160 O O   . MET A 1 596 ? 126.553 155.532 122.055 1.00 74.21  ? 612 MET A O   1 
ATOM 1161 C CB  . MET A 1 596 ? 126.571 152.678 122.119 1.00 77.11  ? 612 MET A CB  1 
ATOM 1162 C CG  . MET A 1 596 ? 125.879 152.933 120.787 1.00 76.06  ? 612 MET A CG  1 
ATOM 1163 S SD  . MET A 1 596 ? 124.440 151.877 120.526 1.00 82.56  ? 612 MET A SD  1 
ATOM 1164 C CE  . MET A 1 596 ? 125.204 150.258 120.468 1.00 77.49  ? 612 MET A CE  1 
ATOM 1165 N N   . GLU A 1 597 ? 128.004 155.521 123.770 1.00 82.23  ? 613 GLU A N   1 
ATOM 1166 C CA  . GLU A 1 597 ? 127.645 156.860 124.203 1.00 79.42  ? 613 GLU A CA  1 
ATOM 1167 C C   . GLU A 1 597 ? 128.218 157.906 123.250 1.00 81.53  ? 613 GLU A C   1 
ATOM 1168 O O   . GLU A 1 597 ? 129.220 157.684 122.563 1.00 83.19  ? 613 GLU A O   1 
ATOM 1169 C CB  . GLU A 1 597 ? 128.150 157.110 125.625 1.00 78.91  ? 613 GLU A CB  1 
ATOM 1170 C CG  . GLU A 1 597 ? 127.755 158.458 126.206 1.00 78.46  ? 613 GLU A CG  1 
ATOM 1171 C CD  . GLU A 1 597 ? 128.202 158.625 127.644 1.00 81.16  ? 613 GLU A CD  1 
ATOM 1172 O OE1 . GLU A 1 597 ? 128.818 157.685 128.190 1.00 85.28  ? 613 GLU A OE1 1 
ATOM 1173 O OE2 . GLU A 1 597 ? 127.938 159.695 128.230 1.00 77.43  ? 613 GLU A OE2 1 
ATOM 1174 N N   . LYS A 1 598 ? 127.560 159.063 123.215 1.00 84.60  ? 614 LYS A N   1 
ATOM 1175 C CA  . LYS A 1 598 ? 127.991 160.192 122.407 1.00 83.97  ? 614 LYS A CA  1 
ATOM 1176 C C   . LYS A 1 598 ? 128.159 161.416 123.295 1.00 87.22  ? 614 LYS A C   1 
ATOM 1177 O O   . LYS A 1 598 ? 127.426 161.602 124.270 1.00 87.17  ? 614 LYS A O   1 
ATOM 1178 C CB  . LYS A 1 598 ? 126.986 160.502 121.290 1.00 86.16  ? 614 LYS A CB  1 
ATOM 1179 C CG  . LYS A 1 598 ? 126.872 159.413 120.235 1.00 90.64  ? 614 LYS A CG  1 
ATOM 1180 C CD  . LYS A 1 598 ? 125.777 159.714 119.218 1.00 89.52  ? 614 LYS A CD  1 
ATOM 1181 C CE  . LYS A 1 598 ? 126.018 161.026 118.484 1.00 86.87  ? 614 LYS A CE  1 
ATOM 1182 N NZ  . LYS A 1 598 ? 127.369 161.085 117.860 1.00 83.84  ? 614 LYS A NZ  1 
ATOM 1183 N N   . ASP A 1 599 ? 129.138 162.254 122.946 1.00 89.22  ? 615 ASP A N   1 
ATOM 1184 C CA  . ASP A 1 599 ? 129.355 163.488 123.689 1.00 86.63  ? 615 ASP A CA  1 
ATOM 1185 C C   . ASP A 1 599 ? 128.175 164.440 123.568 1.00 87.50  ? 615 ASP A C   1 
ATOM 1186 O O   . ASP A 1 599 ? 127.850 165.132 124.539 1.00 87.54  ? 615 ASP A O   1 
ATOM 1187 C CB  . ASP A 1 599 ? 130.630 164.177 123.203 1.00 86.31  ? 615 ASP A CB  1 
ATOM 1188 C CG  . ASP A 1 599 ? 131.865 163.319 123.393 1.00 87.88  ? 615 ASP A CG  1 
ATOM 1189 O OD1 . ASP A 1 599 ? 131.731 162.187 123.902 1.00 85.27  ? 615 ASP A OD1 1 
ATOM 1190 O OD2 . ASP A 1 599 ? 132.969 163.778 123.033 1.00 88.93  ? 615 ASP A OD2 1 
ATOM 1191 N N   . PHE A 1 600 ? 127.531 164.490 122.404 1.00 90.91  ? 616 PHE A N   1 
ATOM 1192 C CA  . PHE A 1 600 ? 126.341 165.302 122.201 1.00 89.11  ? 616 PHE A CA  1 
ATOM 1193 C C   . PHE A 1 600 ? 125.238 164.420 121.640 1.00 91.97  ? 616 PHE A C   1 
ATOM 1194 O O   . PHE A 1 600 ? 125.482 163.599 120.751 1.00 91.77  ? 616 PHE A O   1 
ATOM 1195 C CB  . PHE A 1 600 ? 126.616 166.474 121.253 1.00 86.87  ? 616 PHE A CB  1 
ATOM 1196 C CG  . PHE A 1 600 ? 125.427 167.363 121.030 1.00 89.11  ? 616 PHE A CG  1 
ATOM 1197 C CD1 . PHE A 1 600 ? 125.134 168.384 121.918 1.00 90.39  ? 616 PHE A CD1 1 
ATOM 1198 C CD2 . PHE A 1 600 ? 124.602 167.179 119.934 1.00 92.35  ? 616 PHE A CD2 1 
ATOM 1199 C CE1 . PHE A 1 600 ? 124.041 169.203 121.717 1.00 91.70  ? 616 PHE A CE1 1 
ATOM 1200 C CE2 . PHE A 1 600 ? 123.508 167.995 119.728 1.00 93.66  ? 616 PHE A CE2 1 
ATOM 1201 C CZ  . PHE A 1 600 ? 123.227 169.009 120.620 1.00 92.21  ? 616 PHE A CZ  1 
ATOM 1202 N N   . MET A 1 601 ? 124.027 164.595 122.164 1.00 90.57  ? 617 MET A N   1 
ATOM 1203 C CA  . MET A 1 601 ? 122.879 163.777 121.795 1.00 89.50  ? 617 MET A CA  1 
ATOM 1204 C C   . MET A 1 601 ? 121.756 164.682 121.312 1.00 89.91  ? 617 MET A C   1 
ATOM 1205 O O   . MET A 1 601 ? 121.353 165.610 122.021 1.00 88.79  ? 617 MET A O   1 
ATOM 1206 C CB  . MET A 1 601 ? 122.414 162.927 122.980 1.00 88.77  ? 617 MET A CB  1 
ATOM 1207 C CG  . MET A 1 601 ? 123.342 161.768 123.309 1.00 92.04  ? 617 MET A CG  1 
ATOM 1208 S SD  . MET A 1 601 ? 122.961 160.991 124.891 1.00 100.43 ? 617 MET A SD  1 
ATOM 1209 C CE  . MET A 1 601 ? 123.568 162.234 126.028 1.00 89.69  ? 617 MET A CE  1 
ATOM 1210 N N   . LEU A 1 602 ? 121.255 164.409 120.109 1.00 90.01  ? 618 LEU A N   1 
ATOM 1211 C CA  . LEU A 1 602 ? 120.122 165.128 119.540 1.00 88.65  ? 618 LEU A CA  1 
ATOM 1212 C C   . LEU A 1 602 ? 118.913 164.201 119.561 1.00 87.79  ? 618 LEU A C   1 
ATOM 1213 O O   . LEU A 1 602 ? 118.955 163.103 118.997 1.00 86.53  ? 618 LEU A O   1 
ATOM 1214 C CB  . LEU A 1 602 ? 120.432 165.593 118.119 1.00 90.19  ? 618 LEU A CB  1 
ATOM 1215 C CG  . LEU A 1 602 ? 119.339 166.402 117.419 1.00 91.87  ? 618 LEU A CG  1 
ATOM 1216 C CD1 . LEU A 1 602 ? 119.180 167.767 118.068 1.00 93.23  ? 618 LEU A CD1 1 
ATOM 1217 C CD2 . LEU A 1 602 ? 119.651 166.540 115.938 1.00 90.02  ? 618 LEU A CD2 1 
ATOM 1218 N N   . ILE A 1 603 ? 117.837 164.644 120.205 1.00 78.80  ? 619 ILE A N   1 
ATOM 1219 C CA  . ILE A 1 603 ? 116.638 163.836 120.387 1.00 78.35  ? 619 ILE A CA  1 
ATOM 1220 C C   . ILE A 1 603 ? 115.557 164.345 119.445 1.00 80.38  ? 619 ILE A C   1 
ATOM 1221 O O   . ILE A 1 603 ? 115.347 165.558 119.323 1.00 83.06  ? 619 ILE A O   1 
ATOM 1222 C CB  . ILE A 1 603 ? 116.152 163.870 121.846 1.00 75.70  ? 619 ILE A CB  1 
ATOM 1223 C CG1 . ILE A 1 603 ? 117.251 163.378 122.795 1.00 76.30  ? 619 ILE A CG1 1 
ATOM 1224 C CG2 . ILE A 1 603 ? 114.897 163.020 122.000 1.00 79.42  ? 619 ILE A CG2 1 
ATOM 1225 C CD1 . ILE A 1 603 ? 118.197 164.467 123.263 1.00 76.69  ? 619 ILE A CD1 1 
ATOM 1226 N N   . GLY A 1 604 ? 114.875 163.418 118.778 1.00 85.35  ? 620 GLY A N   1 
ATOM 1227 C CA  . GLY A 1 604 ? 113.754 163.761 117.928 1.00 85.51  ? 620 GLY A CA  1 
ATOM 1228 C C   . GLY A 1 604 ? 112.492 163.968 118.737 1.00 82.60  ? 620 GLY A C   1 
ATOM 1229 O O   . GLY A 1 604 ? 111.636 163.080 118.803 1.00 80.46  ? 620 GLY A O   1 
ATOM 1230 N N   . HIS A 1 605 ? 112.378 165.136 119.366 1.00 85.46  ? 621 HIS A N   1 
ATOM 1231 C CA  . HIS A 1 605 ? 111.311 165.430 120.315 1.00 84.51  ? 621 HIS A CA  1 
ATOM 1232 C C   . HIS A 1 605 ? 109.958 164.943 119.815 1.00 83.78  ? 621 HIS A C   1 
ATOM 1233 O O   . HIS A 1 605 ? 109.442 165.428 118.802 1.00 88.34  ? 621 HIS A O   1 
ATOM 1234 C CB  . HIS A 1 605 ? 111.262 166.938 120.578 1.00 86.00  ? 621 HIS A CB  1 
ATOM 1235 C CG  . HIS A 1 605 ? 110.170 167.349 121.514 1.00 87.44  ? 621 HIS A CG  1 
ATOM 1236 N ND1 . HIS A 1 605 ? 110.267 167.205 122.881 1.00 86.52  ? 621 HIS A ND1 1 
ATOM 1237 C CD2 . HIS A 1 605 ? 108.952 167.892 121.279 1.00 88.80  ? 621 HIS A CD2 1 
ATOM 1238 C CE1 . HIS A 1 605 ? 109.159 167.647 123.448 1.00 85.96  ? 621 HIS A CE1 1 
ATOM 1239 N NE2 . HIS A 1 605 ? 108.344 168.068 122.498 1.00 88.44  ? 621 HIS A NE2 1 
ATOM 1240 N N   . ARG A 1 606 ? 109.382 163.985 120.544 1.00 91.36  ? 622 ARG A N   1 
ATOM 1241 C CA  . ARG A 1 606 ? 108.069 163.414 120.233 1.00 91.47  ? 622 ARG A CA  1 
ATOM 1242 C C   . ARG A 1 606 ? 107.902 163.145 118.739 1.00 93.30  ? 622 ARG A C   1 
ATOM 1243 O O   . ARG A 1 606 ? 106.914 163.550 118.124 1.00 96.53  ? 622 ARG A O   1 
ATOM 1244 C CB  . ARG A 1 606 ? 106.947 164.316 120.755 1.00 93.64  ? 622 ARG A CB  1 
ATOM 1245 C CG  . ARG A 1 606 ? 106.951 164.437 122.270 1.00 92.12  ? 622 ARG A CG  1 
ATOM 1246 C CD  . ARG A 1 606 ? 105.635 164.964 122.811 1.00 94.32  ? 622 ARG A CD  1 
ATOM 1247 N NE  . ARG A 1 606 ? 105.487 164.651 124.228 1.00 95.42  ? 622 ARG A NE  1 
ATOM 1248 C CZ  . ARG A 1 606 ? 106.005 165.369 125.217 1.00 97.87  ? 622 ARG A CZ  1 
ATOM 1249 N NH1 . ARG A 1 606 ? 106.700 166.470 124.984 1.00 96.83  ? 622 ARG A NH1 1 
ATOM 1250 N NH2 . ARG A 1 606 ? 105.825 164.968 126.472 1.00 96.45  ? 622 ARG A NH2 1 
ATOM 1251 N N   . GLY A 1 607 ? 108.874 162.455 118.149 1.00 89.06  ? 623 GLY A N   1 
ATOM 1252 C CA  . GLY A 1 607 ? 108.775 162.042 116.765 1.00 90.54  ? 623 GLY A CA  1 
ATOM 1253 C C   . GLY A 1 607 ? 109.063 163.116 115.744 1.00 94.42  ? 623 GLY A C   1 
ATOM 1254 O O   . GLY A 1 607 ? 108.734 162.935 114.566 1.00 92.90  ? 623 GLY A O   1 
ATOM 1255 N N   . ALA A 1 608 ? 109.673 164.229 116.149 1.00 98.31  ? 624 ALA A N   1 
ATOM 1256 C CA  . ALA A 1 608 ? 109.962 165.332 115.233 1.00 97.09  ? 624 ALA A CA  1 
ATOM 1257 C C   . ALA A 1 608 ? 108.692 165.796 114.525 1.00 96.30  ? 624 ALA A C   1 
ATOM 1258 O O   . ALA A 1 608 ? 108.652 165.930 113.301 1.00 95.85  ? 624 ALA A O   1 
ATOM 1259 C CB  . ALA A 1 608 ? 111.036 164.937 114.218 1.00 96.12  ? 624 ALA A CB  1 
ATOM 1260 N N   . THR A 1 609 ? 107.642 166.047 115.309 1.00 101.49 ? 625 THR A N   1 
ATOM 1261 C CA  . THR A 1 609 ? 106.350 166.422 114.747 1.00 102.98 ? 625 THR A CA  1 
ATOM 1262 C C   . THR A 1 609 ? 106.385 167.764 114.029 1.00 101.10 ? 625 THR A C   1 
ATOM 1263 O O   . THR A 1 609 ? 105.437 168.081 113.302 1.00 99.21  ? 625 THR A O   1 
ATOM 1264 C CB  . THR A 1 609 ? 105.289 166.461 115.852 1.00 103.15 ? 625 THR A CB  1 
ATOM 1265 O OG1 . THR A 1 609 ? 104.011 166.773 115.283 1.00 105.01 ? 625 THR A OG1 1 
ATOM 1266 C CG2 . THR A 1 609 ? 105.638 167.503 116.913 1.00 99.64  ? 625 THR A CG2 1 
ATOM 1267 N N   . GLY A 1 610 ? 107.441 168.556 114.211 1.00 99.82  ? 626 GLY A N   1 
ATOM 1268 C CA  . GLY A 1 610 ? 107.522 169.835 113.532 1.00 98.17  ? 626 GLY A CA  1 
ATOM 1269 C C   . GLY A 1 610 ? 107.481 169.710 112.022 1.00 97.01  ? 626 GLY A C   1 
ATOM 1270 O O   . GLY A 1 610 ? 107.049 170.636 111.330 1.00 97.58  ? 626 GLY A O   1 
ATOM 1271 N N   . TYR A 1 611 ? 107.927 168.570 111.491 1.00 97.11  ? 627 TYR A N   1 
ATOM 1272 C CA  . TYR A 1 611 ? 107.955 168.340 110.053 1.00 97.48  ? 627 TYR A CA  1 
ATOM 1273 C C   . TYR A 1 611 ? 106.896 167.358 109.569 1.00 98.54  ? 627 TYR A C   1 
ATOM 1274 O O   . TYR A 1 611 ? 106.614 167.328 108.366 1.00 97.70  ? 627 TYR A O   1 
ATOM 1275 C CB  . TYR A 1 611 ? 109.336 167.825 109.625 1.00 95.14  ? 627 TYR A CB  1 
ATOM 1276 C CG  . TYR A 1 611 ? 110.357 168.920 109.409 1.00 95.74  ? 627 TYR A CG  1 
ATOM 1277 C CD1 . TYR A 1 611 ? 110.386 169.643 108.224 1.00 97.18  ? 627 TYR A CD1 1 
ATOM 1278 C CD2 . TYR A 1 611 ? 111.293 169.229 110.387 1.00 97.20  ? 627 TYR A CD2 1 
ATOM 1279 C CE1 . TYR A 1 611 ? 111.315 170.644 108.019 1.00 96.35  ? 627 TYR A CE1 1 
ATOM 1280 C CE2 . TYR A 1 611 ? 112.228 170.230 110.191 1.00 99.12  ? 627 TYR A CE2 1 
ATOM 1281 C CZ  . TYR A 1 611 ? 112.233 170.934 109.005 1.00 98.62  ? 627 TYR A CZ  1 
ATOM 1282 O OH  . TYR A 1 611 ? 113.159 171.930 108.803 1.00 97.41  ? 627 TYR A OH  1 
ATOM 1283 N N   . THR A 1 612 ? 106.305 166.564 110.455 1.00 104.82 ? 628 THR A N   1 
ATOM 1284 C CA  . THR A 1 612 ? 105.340 165.546 110.049 1.00 104.84 ? 628 THR A CA  1 
ATOM 1285 C C   . THR A 1 612 ? 104.461 165.209 111.247 1.00 105.96 ? 628 THR A C   1 
ATOM 1286 O O   . THR A 1 612 ? 104.467 165.910 112.264 1.00 106.22 ? 628 THR A O   1 
ATOM 1287 C CB  . THR A 1 612 ? 106.039 164.297 109.507 1.00 103.61 ? 628 THR A CB  1 
ATOM 1288 O OG1 . THR A 1 612 ? 105.058 163.328 109.117 1.00 104.52 ? 628 THR A OG1 1 
ATOM 1289 C CG2 . THR A 1 612 ? 106.958 163.689 110.560 1.00 103.51 ? 628 THR A CG2 1 
ATOM 1290 N N   . ASP A 1 613 ? 103.699 164.126 111.114 1.00 105.94 ? 629 ASP A N   1 
ATOM 1291 C CA  . ASP A 1 613 ? 102.796 163.706 112.177 1.00 104.56 ? 629 ASP A CA  1 
ATOM 1292 C C   . ASP A 1 613 ? 103.585 163.207 113.382 1.00 106.63 ? 629 ASP A C   1 
ATOM 1293 O O   . ASP A 1 613 ? 104.720 162.741 113.255 1.00 104.93 ? 629 ASP A O   1 
ATOM 1294 C CB  . ASP A 1 613 ? 101.858 162.610 111.670 1.00 104.32 ? 629 ASP A CB  1 
ATOM 1295 C CG  . ASP A 1 613 ? 100.792 162.240 112.683 1.00 107.19 ? 629 ASP A CG  1 
ATOM 1296 O OD1 . ASP A 1 613 ? 100.724 162.893 113.745 1.00 105.22 ? 629 ASP A OD1 1 
ATOM 1297 O OD2 . ASP A 1 613 ? 100.022 161.294 112.416 1.00 108.72 ? 629 ASP A OD2 1 
ATOM 1298 N N   . GLU A 1 614 ? 102.972 163.308 114.558 1.00 102.95 ? 630 GLU A N   1 
ATOM 1299 C CA  . GLU A 1 614 ? 103.642 162.923 115.789 1.00 99.48  ? 630 GLU A CA  1 
ATOM 1300 C C   . GLU A 1 614 ? 103.406 161.446 116.103 1.00 98.86  ? 630 GLU A C   1 
ATOM 1301 O O   . GLU A 1 614 ? 102.351 160.877 115.809 1.00 99.52  ? 630 GLU A O   1 
ATOM 1302 C CB  . GLU A 1 614 ? 103.154 163.781 116.957 1.00 98.44  ? 630 GLU A CB  1 
ATOM 1303 C CG  . GLU A 1 614 ? 101.692 163.568 117.322 1.00 100.66 ? 630 GLU A CG  1 
ATOM 1304 C CD  . GLU A 1 614 ? 101.259 164.409 118.505 1.00 102.04 ? 630 GLU A CD  1 
ATOM 1305 O OE1 . GLU A 1 614 ? 102.058 165.254 118.961 1.00 97.93  ? 630 GLU A OE1 1 
ATOM 1306 O OE2 . GLU A 1 614 ? 100.119 164.223 118.980 1.00 105.58 ? 630 GLU A OE2 1 
ATOM 1307 N N   . HIS A 1 615 ? 104.414 160.832 116.716 1.00 96.49  ? 631 HIS A N   1 
ATOM 1308 C CA  . HIS A 1 615 ? 104.323 159.471 117.241 1.00 97.91  ? 631 HIS A CA  1 
ATOM 1309 C C   . HIS A 1 615 ? 103.772 158.502 116.197 1.00 98.96  ? 631 HIS A C   1 
ATOM 1310 O O   . HIS A 1 615 ? 102.697 157.918 116.349 1.00 99.24  ? 631 HIS A O   1 
ATOM 1311 C CB  . HIS A 1 615 ? 103.478 159.437 118.513 1.00 96.54  ? 631 HIS A CB  1 
ATOM 1312 C CG  . HIS A 1 615 ? 104.120 160.123 119.678 1.00 97.21  ? 631 HIS A CG  1 
ATOM 1313 N ND1 . HIS A 1 615 ? 105.378 159.792 120.134 1.00 99.16  ? 631 HIS A ND1 1 
ATOM 1314 C CD2 . HIS A 1 615 ? 103.678 161.119 120.482 1.00 97.37  ? 631 HIS A CD2 1 
ATOM 1315 C CE1 . HIS A 1 615 ? 105.685 160.556 121.167 1.00 99.04  ? 631 HIS A CE1 1 
ATOM 1316 N NE2 . HIS A 1 615 ? 104.670 161.370 121.399 1.00 96.19  ? 631 HIS A NE2 1 
ATOM 1317 N N   . THR A 1 616 ? 104.533 158.336 115.118 1.00 100.11 ? 632 THR A N   1 
ATOM 1318 C CA  . THR A 1 616 ? 104.224 157.335 114.108 1.00 98.83  ? 632 THR A CA  1 
ATOM 1319 C C   . THR A 1 616 ? 105.527 156.838 113.498 1.00 95.71  ? 632 THR A C   1 
ATOM 1320 O O   . THR A 1 616 ? 106.556 157.517 113.544 1.00 96.44  ? 632 THR A O   1 
ATOM 1321 C CB  . THR A 1 616 ? 103.292 157.888 113.020 1.00 98.77  ? 632 THR A CB  1 
ATOM 1322 O OG1 . THR A 1 616 ? 102.948 156.841 112.103 1.00 99.15  ? 632 THR A OG1 1 
ATOM 1323 C CG2 . THR A 1 616 ? 103.958 159.022 112.260 1.00 95.77  ? 632 THR A CG2 1 
ATOM 1324 N N   . ILE A 1 617 ? 105.470 155.635 112.923 1.00 86.72  ? 633 ILE A N   1 
ATOM 1325 C CA  . ILE A 1 617 ? 106.677 155.010 112.386 1.00 89.89  ? 633 ILE A CA  1 
ATOM 1326 C C   . ILE A 1 617 ? 107.292 155.887 111.304 1.00 89.96  ? 633 ILE A C   1 
ATOM 1327 O O   . ILE A 1 617 ? 108.518 156.047 111.234 1.00 89.87  ? 633 ILE A O   1 
ATOM 1328 C CB  . ILE A 1 617 ? 106.358 153.599 111.859 1.00 89.73  ? 633 ILE A CB  1 
ATOM 1329 C CG1 . ILE A 1 617 ? 105.869 152.706 113.004 1.00 89.28  ? 633 ILE A CG1 1 
ATOM 1330 C CG2 . ILE A 1 617 ? 107.585 152.994 111.180 1.00 86.60  ? 633 ILE A CG2 1 
ATOM 1331 C CD1 . ILE A 1 617 ? 105.385 151.339 112.562 1.00 87.59  ? 633 ILE A CD1 1 
ATOM 1332 N N   . LYS A 1 618 ? 106.455 156.464 110.439 1.00 91.87  ? 634 LYS A N   1 
ATOM 1333 C CA  . LYS A 1 618 ? 106.968 157.345 109.396 1.00 93.45  ? 634 LYS A CA  1 
ATOM 1334 C C   . LYS A 1 618 ? 107.674 158.551 110.001 1.00 92.74  ? 634 LYS A C   1 
ATOM 1335 O O   . LYS A 1 618 ? 108.738 158.961 109.524 1.00 91.16  ? 634 LYS A O   1 
ATOM 1336 C CB  . LYS A 1 618 ? 105.825 157.790 108.484 1.00 92.03  ? 634 LYS A CB  1 
ATOM 1337 C CG  . LYS A 1 618 ? 106.266 158.608 107.280 1.00 91.27  ? 634 LYS A CG  1 
ATOM 1338 C CD  . LYS A 1 618 ? 105.097 158.890 106.349 1.00 89.11  ? 634 LYS A CD  1 
ATOM 1339 C CE  . LYS A 1 618 ? 105.533 159.675 105.124 1.00 90.35  ? 634 LYS A CE  1 
ATOM 1340 N NZ  . LYS A 1 618 ? 106.070 161.016 105.481 1.00 90.64  ? 634 LYS A NZ  1 
ATOM 1341 N N   . GLY A 1 619 ? 107.099 159.128 111.057 1.00 93.53  ? 635 GLY A N   1 
ATOM 1342 C CA  . GLY A 1 619 ? 107.736 160.266 111.700 1.00 94.15  ? 635 GLY A CA  1 
ATOM 1343 C C   . GLY A 1 619 ? 109.072 159.905 112.320 1.00 94.77  ? 635 GLY A C   1 
ATOM 1344 O O   . GLY A 1 619 ? 110.046 160.654 112.210 1.00 92.72  ? 635 GLY A O   1 
ATOM 1345 N N   . TYR A 1 620 ? 109.134 158.751 112.988 1.00 91.07  ? 636 TYR A N   1 
ATOM 1346 C CA  . TYR A 1 620 ? 110.395 158.308 113.573 1.00 88.92  ? 636 TYR A CA  1 
ATOM 1347 C C   . TYR A 1 620 ? 111.449 158.084 112.497 1.00 88.04  ? 636 TYR A C   1 
ATOM 1348 O O   . TYR A 1 620 ? 112.613 158.468 112.665 1.00 87.44  ? 636 TYR A O   1 
ATOM 1349 C CB  . TYR A 1 620 ? 110.178 157.027 114.379 1.00 85.06  ? 636 TYR A CB  1 
ATOM 1350 C CG  . TYR A 1 620 ? 109.202 157.165 115.528 1.00 86.18  ? 636 TYR A CG  1 
ATOM 1351 C CD1 . TYR A 1 620 ? 109.059 158.368 116.209 1.00 85.74  ? 636 TYR A CD1 1 
ATOM 1352 C CD2 . TYR A 1 620 ? 108.423 156.089 115.932 1.00 87.40  ? 636 TYR A CD2 1 
ATOM 1353 C CE1 . TYR A 1 620 ? 108.170 158.493 117.259 1.00 85.95  ? 636 TYR A CE1 1 
ATOM 1354 C CE2 . TYR A 1 620 ? 107.531 156.206 116.980 1.00 86.14  ? 636 TYR A CE2 1 
ATOM 1355 C CZ  . TYR A 1 620 ? 107.408 157.409 117.639 1.00 86.85  ? 636 TYR A CZ  1 
ATOM 1356 O OH  . TYR A 1 620 ? 106.521 157.527 118.683 1.00 85.27  ? 636 TYR A OH  1 
ATOM 1357 N N   . GLN A 1 621 ? 111.062 157.458 111.383 1.00 91.72  ? 637 GLN A N   1 
ATOM 1358 C CA  . GLN A 1 621 ? 112.014 157.226 110.303 1.00 91.21  ? 637 GLN A CA  1 
ATOM 1359 C C   . GLN A 1 621 ? 112.493 158.542 109.701 1.00 95.56  ? 637 GLN A C   1 
ATOM 1360 O O   . GLN A 1 621 ? 113.681 158.695 109.393 1.00 93.00  ? 637 GLN A O   1 
ATOM 1361 C CB  . GLN A 1 621 ? 111.382 156.337 109.233 1.00 93.93  ? 637 GLN A CB  1 
ATOM 1362 C CG  . GLN A 1 621 ? 112.375 155.774 108.231 1.00 93.44  ? 637 GLN A CG  1 
ATOM 1363 C CD  . GLN A 1 621 ? 111.788 154.649 107.401 1.00 93.22  ? 637 GLN A CD  1 
ATOM 1364 O OE1 . GLN A 1 621 ? 111.952 153.473 107.726 1.00 91.24  ? 637 GLN A OE1 1 
ATOM 1365 N NE2 . GLN A 1 621 ? 111.100 155.004 106.323 1.00 92.02  ? 637 GLN A NE2 1 
ATOM 1366 N N   . MET A 1 622 ? 111.585 159.505 109.526 1.00 100.58 ? 638 MET A N   1 
ATOM 1367 C CA  . MET A 1 622 ? 111.987 160.812 109.016 1.00 95.83  ? 638 MET A CA  1 
ATOM 1368 C C   . MET A 1 622 ? 112.947 161.504 109.975 1.00 94.31  ? 638 MET A C   1 
ATOM 1369 O O   . MET A 1 622 ? 113.931 162.117 109.546 1.00 94.82  ? 638 MET A O   1 
ATOM 1370 C CB  . MET A 1 622 ? 110.754 161.682 108.774 1.00 93.38  ? 638 MET A CB  1 
ATOM 1371 C CG  . MET A 1 622 ? 109.895 161.223 107.609 1.00 96.69  ? 638 MET A CG  1 
ATOM 1372 S SD  . MET A 1 622 ? 108.356 162.151 107.461 1.00 101.82 ? 638 MET A SD  1 
ATOM 1373 C CE  . MET A 1 622 ? 108.980 163.812 107.216 1.00 96.04  ? 638 MET A CE  1 
ATOM 1374 N N   . ALA A 1 623 ? 112.675 161.421 111.279 1.00 91.44  ? 639 ALA A N   1 
ATOM 1375 C CA  . ALA A 1 623 ? 113.573 162.024 112.258 1.00 94.52  ? 639 ALA A CA  1 
ATOM 1376 C C   . ALA A 1 623 ? 114.949 161.375 112.208 1.00 92.61  ? 639 ALA A C   1 
ATOM 1377 O O   . ALA A 1 623 ? 115.974 162.063 112.272 1.00 91.67  ? 639 ALA A O   1 
ATOM 1378 C CB  . ALA A 1 623 ? 112.974 161.908 113.659 1.00 92.37  ? 639 ALA A CB  1 
ATOM 1379 N N   . LEU A 1 624 ? 114.991 160.046 112.096 1.00 86.80  ? 640 LEU A N   1 
ATOM 1380 C CA  . LEU A 1 624 ? 116.272 159.358 111.982 1.00 87.16  ? 640 LEU A CA  1 
ATOM 1381 C C   . LEU A 1 624 ? 117.016 159.791 110.726 1.00 88.26  ? 640 LEU A C   1 
ATOM 1382 O O   . LEU A 1 624 ? 118.232 160.014 110.760 1.00 84.75  ? 640 LEU A O   1 
ATOM 1383 C CB  . LEU A 1 624 ? 116.056 157.845 111.981 1.00 84.55  ? 640 LEU A CB  1 
ATOM 1384 C CG  . LEU A 1 624 ? 115.544 157.251 113.294 1.00 84.68  ? 640 LEU A CG  1 
ATOM 1385 C CD1 . LEU A 1 624 ? 115.072 155.824 113.083 1.00 84.51  ? 640 LEU A CD1 1 
ATOM 1386 C CD2 . LEU A 1 624 ? 116.625 157.307 114.363 1.00 82.10  ? 640 LEU A CD2 1 
ATOM 1387 N N   . ASP A 1 625 ? 116.301 159.917 109.606 1.00 99.68  ? 641 ASP A N   1 
ATOM 1388 C CA  . ASP A 1 625 ? 116.936 160.361 108.370 1.00 100.84 ? 641 ASP A CA  1 
ATOM 1389 C C   . ASP A 1 625 ? 117.494 161.772 108.508 1.00 99.00  ? 641 ASP A C   1 
ATOM 1390 O O   . ASP A 1 625 ? 118.595 162.056 108.022 1.00 98.94  ? 641 ASP A O   1 
ATOM 1391 C CB  . ASP A 1 625 ? 115.938 160.294 107.215 1.00 101.35 ? 641 ASP A CB  1 
ATOM 1392 C CG  . ASP A 1 625 ? 115.418 158.890 106.974 1.00 100.52 ? 641 ASP A CG  1 
ATOM 1393 O OD1 . ASP A 1 625 ? 115.832 157.968 107.707 1.00 100.02 ? 641 ASP A OD1 1 
ATOM 1394 O OD2 . ASP A 1 625 ? 114.594 158.710 106.053 1.00 99.23  ? 641 ASP A OD2 1 
ATOM 1395 N N   . LYS A 1 626 ? 116.753 162.666 109.166 1.00 92.45  ? 642 LYS A N   1 
ATOM 1396 C CA  . LYS A 1 626 ? 117.209 164.038 109.349 1.00 92.55  ? 642 LYS A CA  1 
ATOM 1397 C C   . LYS A 1 626 ? 118.402 164.144 110.291 1.00 92.76  ? 642 LYS A C   1 
ATOM 1398 O O   . LYS A 1 626 ? 119.022 165.211 110.354 1.00 90.50  ? 642 LYS A O   1 
ATOM 1399 C CB  . LYS A 1 626 ? 116.062 164.902 109.875 1.00 91.48  ? 642 LYS A CB  1 
ATOM 1400 C CG  . LYS A 1 626 ? 114.945 165.123 108.870 1.00 93.62  ? 642 LYS A CG  1 
ATOM 1401 C CD  . LYS A 1 626 ? 113.785 165.888 109.485 1.00 92.32  ? 642 LYS A CD  1 
ATOM 1402 C CE  . LYS A 1 626 ? 112.698 166.172 108.461 1.00 93.46  ? 642 LYS A CE  1 
ATOM 1403 N NZ  . LYS A 1 626 ? 113.169 167.074 107.373 1.00 92.86  ? 642 LYS A NZ  1 
ATOM 1404 N N   . GLY A 1 627 ? 118.734 163.084 111.014 1.00 94.40  ? 643 GLY A N   1 
ATOM 1405 C CA  . GLY A 1 627 ? 119.879 163.069 111.893 1.00 92.43  ? 643 GLY A CA  1 
ATOM 1406 C C   . GLY A 1 627 ? 119.576 162.928 113.377 1.00 91.39  ? 643 GLY A C   1 
ATOM 1407 O O   . GLY A 1 627 ? 120.417 163.320 114.195 1.00 89.35  ? 643 GLY A O   1 
ATOM 1408 N N   . ALA A 1 628 ? 118.417 162.389 113.745 1.00 93.11  ? 644 ALA A N   1 
ATOM 1409 C CA  . ALA A 1 628 ? 118.079 162.244 115.154 1.00 91.59  ? 644 ALA A CA  1 
ATOM 1410 C C   . ALA A 1 628 ? 118.884 161.114 115.783 1.00 90.71  ? 644 ALA A C   1 
ATOM 1411 O O   . ALA A 1 628 ? 118.895 159.986 115.279 1.00 90.74  ? 644 ALA A O   1 
ATOM 1412 C CB  . ALA A 1 628 ? 116.583 161.975 115.312 1.00 90.63  ? 644 ALA A CB  1 
ATOM 1413 N N   . ASP A 1 629 ? 119.559 161.420 116.892 1.00 87.03  ? 645 ASP A N   1 
ATOM 1414 C CA  . ASP A 1 629 ? 120.304 160.397 117.614 1.00 88.02  ? 645 ASP A CA  1 
ATOM 1415 C C   . ASP A 1 629 ? 119.388 159.501 118.436 1.00 87.90  ? 645 ASP A C   1 
ATOM 1416 O O   . ASP A 1 629 ? 119.649 158.298 118.556 1.00 86.26  ? 645 ASP A O   1 
ATOM 1417 C CB  . ASP A 1 629 ? 121.346 161.049 118.524 1.00 87.12  ? 645 ASP A CB  1 
ATOM 1418 C CG  . ASP A 1 629 ? 122.316 161.928 117.762 1.00 89.75  ? 645 ASP A CG  1 
ATOM 1419 O OD1 . ASP A 1 629 ? 122.574 161.639 116.575 1.00 88.81  ? 645 ASP A OD1 1 
ATOM 1420 O OD2 . ASP A 1 629 ? 122.820 162.907 118.350 1.00 93.68  ? 645 ASP A OD2 1 
ATOM 1421 N N   . TYR A 1 630 ? 118.322 160.061 119.004 1.00 80.77  ? 646 TYR A N   1 
ATOM 1422 C CA  . TYR A 1 630 ? 117.384 159.311 119.824 1.00 76.94  ? 646 TYR A CA  1 
ATOM 1423 C C   . TYR A 1 630 ? 115.963 159.718 119.467 1.00 73.15  ? 646 TYR A C   1 
ATOM 1424 O O   . TYR A 1 630 ? 115.686 160.899 119.240 1.00 78.44  ? 646 TYR A O   1 
ATOM 1425 C CB  . TYR A 1 630 ? 117.625 159.554 121.318 1.00 80.27  ? 646 TYR A CB  1 
ATOM 1426 C CG  . TYR A 1 630 ? 118.891 158.928 121.855 1.00 78.17  ? 646 TYR A CG  1 
ATOM 1427 C CD1 . TYR A 1 630 ? 120.128 159.521 121.642 1.00 75.73  ? 646 TYR A CD1 1 
ATOM 1428 C CD2 . TYR A 1 630 ? 118.847 157.751 122.587 1.00 79.21  ? 646 TYR A CD2 1 
ATOM 1429 C CE1 . TYR A 1 630 ? 121.286 158.954 122.135 1.00 75.19  ? 646 TYR A CE1 1 
ATOM 1430 C CE2 . TYR A 1 630 ? 119.999 157.177 123.086 1.00 79.51  ? 646 TYR A CE2 1 
ATOM 1431 C CZ  . TYR A 1 630 ? 121.215 157.782 122.857 1.00 75.78  ? 646 TYR A CZ  1 
ATOM 1432 O OH  . TYR A 1 630 ? 122.363 157.210 123.352 1.00 76.39  ? 646 TYR A OH  1 
ATOM 1433 N N   . ILE A 1 631 ? 115.070 158.735 119.421 1.00 69.65  ? 647 ILE A N   1 
ATOM 1434 C CA  . ILE A 1 631 ? 113.651 159.003 119.227 1.00 72.33  ? 647 ILE A CA  1 
ATOM 1435 C C   . ILE A 1 631 ? 112.950 158.968 120.577 1.00 72.19  ? 647 ILE A C   1 
ATOM 1436 O O   . ILE A 1 631 ? 113.267 158.150 121.448 1.00 79.66  ? 647 ILE A O   1 
ATOM 1437 C CB  . ILE A 1 631 ? 113.033 157.994 118.237 1.00 74.04  ? 647 ILE A CB  1 
ATOM 1438 C CG1 . ILE A 1 631 ? 113.109 156.568 118.789 1.00 74.53  ? 647 ILE A CG1 1 
ATOM 1439 C CG2 . ILE A 1 631 ? 113.745 158.071 116.899 1.00 76.93  ? 647 ILE A CG2 1 
ATOM 1440 C CD1 . ILE A 1 631 ? 112.517 155.527 117.858 1.00 75.05  ? 647 ILE A CD1 1 
ATOM 1441 N N   . GLU A 1 632 ? 111.986 159.865 120.757 1.00 73.03  ? 648 GLU A N   1 
ATOM 1442 C CA  . GLU A 1 632 ? 111.262 160.004 122.012 1.00 75.76  ? 648 GLU A CA  1 
ATOM 1443 C C   . GLU A 1 632 ? 109.919 159.299 121.900 1.00 77.51  ? 648 GLU A C   1 
ATOM 1444 O O   . GLU A 1 632 ? 109.192 159.490 120.919 1.00 80.78  ? 648 GLU A O   1 
ATOM 1445 C CB  . GLU A 1 632 ? 111.059 161.477 122.368 1.00 79.31  ? 648 GLU A CB  1 
ATOM 1446 C CG  . GLU A 1 632 ? 110.472 161.700 123.749 1.00 78.95  ? 648 GLU A CG  1 
ATOM 1447 C CD  . GLU A 1 632 ? 110.277 163.168 124.071 1.00 78.75  ? 648 GLU A CD  1 
ATOM 1448 O OE1 . GLU A 1 632 ? 110.467 164.007 123.166 1.00 83.11  ? 648 GLU A OE1 1 
ATOM 1449 O OE2 . GLU A 1 632 ? 109.934 163.483 125.230 1.00 78.82  ? 648 GLU A OE2 1 
ATOM 1450 N N   . LEU A 1 633 ? 109.598 158.485 122.901 1.00 70.57  ? 649 LEU A N   1 
ATOM 1451 C CA  . LEU A 1 633 ? 108.364 157.712 122.932 1.00 70.83  ? 649 LEU A CA  1 
ATOM 1452 C C   . LEU A 1 633 ? 107.562 158.070 124.174 1.00 75.24  ? 649 LEU A C   1 
ATOM 1453 O O   . LEU A 1 633 ? 108.104 158.092 125.285 1.00 79.05  ? 649 LEU A O   1 
ATOM 1454 C CB  . LEU A 1 633 ? 108.662 156.212 122.918 1.00 70.91  ? 649 LEU A CB  1 
ATOM 1455 C CG  . LEU A 1 633 ? 109.501 155.705 121.745 1.00 72.63  ? 649 LEU A CG  1 
ATOM 1456 C CD1 . LEU A 1 633 ? 109.742 154.211 121.875 1.00 76.03  ? 649 LEU A CD1 1 
ATOM 1457 C CD2 . LEU A 1 633 ? 108.833 156.025 120.418 1.00 74.33  ? 649 LEU A CD2 1 
ATOM 1458 N N   . ASP A 1 634 ? 106.277 158.349 123.981 1.00 83.31  ? 650 ASP A N   1 
ATOM 1459 C CA  . ASP A 1 634 ? 105.334 158.560 125.069 1.00 78.70  ? 650 ASP A CA  1 
ATOM 1460 C C   . ASP A 1 634 ? 104.328 157.418 125.072 1.00 82.30  ? 650 ASP A C   1 
ATOM 1461 O O   . ASP A 1 634 ? 103.718 157.116 124.042 1.00 86.14  ? 650 ASP A O   1 
ATOM 1462 C CB  . ASP A 1 634 ? 104.615 159.902 124.922 1.00 81.36  ? 650 ASP A CB  1 
ATOM 1463 C CG  . ASP A 1 634 ? 105.568 161.080 124.952 1.00 85.03  ? 650 ASP A CG  1 
ATOM 1464 O OD1 . ASP A 1 634 ? 106.623 160.977 125.614 1.00 85.35  ? 650 ASP A OD1 1 
ATOM 1465 O OD2 . ASP A 1 634 ? 105.264 162.109 124.313 1.00 90.48  ? 650 ASP A OD2 1 
ATOM 1466 N N   . LEU A 1 635 ? 104.153 156.790 126.233 1.00 78.59  ? 651 LEU A N   1 
ATOM 1467 C CA  . LEU A 1 635 ? 103.401 155.549 126.329 1.00 80.41  ? 651 LEU A CA  1 
ATOM 1468 C C   . LEU A 1 635 ? 102.313 155.674 127.385 1.00 83.80  ? 651 LEU A C   1 
ATOM 1469 O O   . LEU A 1 635 ? 102.496 156.324 128.417 1.00 86.34  ? 651 LEU A O   1 
ATOM 1470 C CB  . LEU A 1 635 ? 104.323 154.371 126.672 1.00 80.34  ? 651 LEU A CB  1 
ATOM 1471 C CG  . LEU A 1 635 ? 105.511 154.158 125.732 1.00 78.73  ? 651 LEU A CG  1 
ATOM 1472 C CD1 . LEU A 1 635 ? 106.424 153.069 126.270 1.00 78.96  ? 651 LEU A CD1 1 
ATOM 1473 C CD2 . LEU A 1 635 ? 105.041 153.815 124.329 1.00 82.69  ? 651 LEU A CD2 1 
ATOM 1474 N N   . GLN A 1 636 ? 101.173 155.042 127.108 1.00 86.11  ? 652 GLN A N   1 
ATOM 1475 C CA  . GLN A 1 636 ? 100.080 154.933 128.063 1.00 85.93  ? 652 GLN A CA  1 
ATOM 1476 C C   . GLN A 1 636 ? 99.454  153.553 127.938 1.00 84.30  ? 652 GLN A C   1 
ATOM 1477 O O   . GLN A 1 636 ? 99.483  152.936 126.870 1.00 83.54  ? 652 GLN A O   1 
ATOM 1478 C CB  . GLN A 1 636 ? 99.003  156.008 127.842 1.00 88.24  ? 652 GLN A CB  1 
ATOM 1479 C CG  . GLN A 1 636 ? 99.475  157.437 128.066 1.00 88.15  ? 652 GLN A CG  1 
ATOM 1480 C CD  . GLN A 1 636 ? 100.248 157.990 126.887 1.00 88.02  ? 652 GLN A CD  1 
ATOM 1481 O OE1 . GLN A 1 636 ? 100.391 157.329 125.858 1.00 87.28  ? 652 GLN A OE1 1 
ATOM 1482 N NE2 . GLN A 1 636 ? 100.753 159.209 127.030 1.00 88.10  ? 652 GLN A NE2 1 
ATOM 1483 N N   . LEU A 1 637 ? 98.888  153.072 129.042 1.00 88.97  ? 653 LEU A N   1 
ATOM 1484 C CA  . LEU A 1 637 ? 98.242  151.767 129.033 1.00 91.87  ? 653 LEU A CA  1 
ATOM 1485 C C   . LEU A 1 637 ? 96.837  151.868 128.455 1.00 90.34  ? 653 LEU A C   1 
ATOM 1486 O O   . LEU A 1 637 ? 96.076  152.785 128.778 1.00 91.33  ? 653 LEU A O   1 
ATOM 1487 C CB  . LEU A 1 637 ? 98.180  151.191 130.449 1.00 91.83  ? 653 LEU A CB  1 
ATOM 1488 C CG  . LEU A 1 637 ? 99.492  150.680 131.046 1.00 89.10  ? 653 LEU A CG  1 
ATOM 1489 C CD1 . LEU A 1 637 ? 99.313  150.381 132.526 1.00 88.22  ? 653 LEU A CD1 1 
ATOM 1490 C CD2 . LEU A 1 637 ? 99.983  149.442 130.308 1.00 87.95  ? 653 LEU A CD2 1 
ATOM 1491 N N   . THR A 1 638 ? 96.494  150.914 127.592 1.00 97.61  ? 654 THR A N   1 
ATOM 1492 C CA  . THR A 1 638 ? 95.138  150.809 127.072 1.00 100.09 ? 654 THR A CA  1 
ATOM 1493 C C   . THR A 1 638 ? 94.269  150.081 128.088 1.00 100.38 ? 654 THR A C   1 
ATOM 1494 O O   . THR A 1 638 ? 94.709  149.828 129.214 1.00 100.66 ? 654 THR A O   1 
ATOM 1495 C CB  . THR A 1 638 ? 95.120  150.072 125.730 1.00 100.29 ? 654 THR A CB  1 
ATOM 1496 O OG1 . THR A 1 638 ? 95.496  148.704 125.928 1.00 97.07  ? 654 THR A OG1 1 
ATOM 1497 C CG2 . THR A 1 638 ? 96.084  150.722 124.747 1.00 101.02 ? 654 THR A CG2 1 
ATOM 1498 N N   . LYS A 1 639 ? 93.034  149.745 127.710 1.00 106.13 ? 655 LYS A N   1 
ATOM 1499 C CA  . LYS A 1 639 ? 92.199  148.950 128.602 1.00 106.59 ? 655 LYS A CA  1 
ATOM 1500 C C   . LYS A 1 639 ? 92.871  147.625 128.930 1.00 107.52 ? 655 LYS A C   1 
ATOM 1501 O O   . LYS A 1 639 ? 92.742  147.116 130.050 1.00 107.02 ? 655 LYS A O   1 
ATOM 1502 C CB  . LYS A 1 639 ? 90.825  148.717 127.974 1.00 107.64 ? 655 LYS A CB  1 
ATOM 1503 C CG  . LYS A 1 639 ? 89.828  148.048 128.908 1.00 108.01 ? 655 LYS A CG  1 
ATOM 1504 C CD  . LYS A 1 639 ? 88.435  148.003 128.304 1.00 108.16 ? 655 LYS A CD  1 
ATOM 1505 C CE  . LYS A 1 639 ? 87.424  147.436 129.288 1.00 108.77 ? 655 LYS A CE  1 
ATOM 1506 N NZ  . LYS A 1 639 ? 86.040  147.442 128.738 1.00 106.78 ? 655 LYS A NZ  1 
ATOM 1507 N N   . ASP A 1 640 ? 93.590  147.054 127.967 1.00 105.42 ? 656 ASP A N   1 
ATOM 1508 C CA  . ASP A 1 640 ? 94.444  145.908 128.221 1.00 104.85 ? 656 ASP A CA  1 
ATOM 1509 C C   . ASP A 1 640 ? 95.801  146.370 128.745 1.00 104.98 ? 656 ASP A C   1 
ATOM 1510 O O   . ASP A 1 640 ? 96.103  147.565 128.799 1.00 103.73 ? 656 ASP A O   1 
ATOM 1511 C CB  . ASP A 1 640 ? 94.628  145.081 126.948 1.00 105.05 ? 656 ASP A CB  1 
ATOM 1512 C CG  . ASP A 1 640 ? 93.312  144.618 126.358 1.00 105.82 ? 656 ASP A CG  1 
ATOM 1513 O OD1 . ASP A 1 640 ? 92.351  144.417 127.130 1.00 105.78 ? 656 ASP A OD1 1 
ATOM 1514 O OD2 . ASP A 1 640 ? 93.238  144.455 125.122 1.00 105.00 ? 656 ASP A OD2 1 
ATOM 1515 N N   . ASN A 1 641 ? 96.628  145.399 129.129 1.00 100.53 ? 657 ASN A N   1 
ATOM 1516 C CA  . ASN A 1 641 ? 97.956  145.702 129.647 1.00 99.70  ? 657 ASN A CA  1 
ATOM 1517 C C   . ASN A 1 641 ? 98.916  146.198 128.572 1.00 99.17  ? 657 ASN A C   1 
ATOM 1518 O O   . ASN A 1 641 ? 100.019 146.637 128.914 1.00 98.88  ? 657 ASN A O   1 
ATOM 1519 C CB  . ASN A 1 641 ? 98.543  144.466 130.329 1.00 99.06  ? 657 ASN A CB  1 
ATOM 1520 C CG  . ASN A 1 641 ? 97.729  144.021 131.527 1.00 98.43  ? 657 ASN A CG  1 
ATOM 1521 O OD1 . ASN A 1 641 ? 96.889  143.127 131.424 1.00 97.73  ? 657 ASN A OD1 1 
ATOM 1522 N ND2 . ASN A 1 641 ? 97.971  144.646 132.673 1.00 96.75  ? 657 ASN A ND2 1 
ATOM 1523 N N   . LYS A 1 642 ? 98.535  146.140 127.298 1.00 97.58  ? 658 LYS A N   1 
ATOM 1524 C CA  . LYS A 1 642 ? 99.433  146.547 126.228 1.00 94.91  ? 658 LYS A CA  1 
ATOM 1525 C C   . LYS A 1 642 ? 99.693  148.049 126.279 1.00 97.39  ? 658 LYS A C   1 
ATOM 1526 O O   . LYS A 1 642 ? 98.947  148.813 126.898 1.00 101.78 ? 658 LYS A O   1 
ATOM 1527 C CB  . LYS A 1 642 ? 98.850  146.164 124.868 1.00 96.33  ? 658 LYS A CB  1 
ATOM 1528 C CG  . LYS A 1 642 ? 98.453  144.699 124.746 1.00 98.35  ? 658 LYS A CG  1 
ATOM 1529 C CD  . LYS A 1 642 ? 99.633  143.771 124.989 1.00 97.39  ? 658 LYS A CD  1 
ATOM 1530 C CE  . LYS A 1 642 ? 99.233  142.312 124.843 1.00 97.47  ? 658 LYS A CE  1 
ATOM 1531 N NZ  . LYS A 1 642 ? 100.369 141.391 125.120 1.00 96.55  ? 658 LYS A NZ  1 
ATOM 1532 N N   . LEU A 1 643 ? 100.768 148.467 125.616 1.00 83.06  ? 659 LEU A N   1 
ATOM 1533 C CA  . LEU A 1 643 ? 101.222 149.851 125.620 1.00 81.44  ? 659 LEU A CA  1 
ATOM 1534 C C   . LEU A 1 643 ? 100.937 150.494 124.270 1.00 83.27  ? 659 LEU A C   1 
ATOM 1535 O O   . LEU A 1 643 ? 101.174 149.882 123.223 1.00 83.22  ? 659 LEU A O   1 
ATOM 1536 C CB  . LEU A 1 643 ? 102.718 149.930 125.933 1.00 82.65  ? 659 LEU A CB  1 
ATOM 1537 C CG  . LEU A 1 643 ? 103.139 149.468 127.329 1.00 82.58  ? 659 LEU A CG  1 
ATOM 1538 C CD1 . LEU A 1 643 ? 104.643 149.264 127.389 1.00 81.93  ? 659 LEU A CD1 1 
ATOM 1539 C CD2 . LEU A 1 643 ? 102.694 150.474 128.377 1.00 80.87  ? 659 LEU A CD2 1 
ATOM 1540 N N   . LEU A 1 644 ? 100.431 151.724 124.302 1.00 95.21  ? 660 LEU A N   1 
ATOM 1541 C CA  . LEU A 1 644 ? 100.149 152.501 123.104 1.00 96.70  ? 660 LEU A CA  1 
ATOM 1542 C C   . LEU A 1 644 ? 101.020 153.750 123.091 1.00 95.31  ? 660 LEU A C   1 
ATOM 1543 O O   . LEU A 1 644 ? 101.206 154.398 124.126 1.00 95.41  ? 660 LEU A O   1 
ATOM 1544 C CB  . LEU A 1 644 ? 98.671  152.896 123.041 1.00 96.72  ? 660 LEU A CB  1 
ATOM 1545 C CG  . LEU A 1 644 ? 98.215  153.562 121.741 1.00 95.78  ? 660 LEU A CG  1 
ATOM 1546 C CD1 . LEU A 1 644 ? 98.309  152.588 120.576 1.00 98.07  ? 660 LEU A CD1 1 
ATOM 1547 C CD2 . LEU A 1 644 ? 96.800  154.097 121.882 1.00 97.54  ? 660 LEU A CD2 1 
ATOM 1548 N N   . CYS A 1 645 ? 101.548 154.086 121.916 1.00 97.79  ? 661 CYS A N   1 
ATOM 1549 C CA  . CYS A 1 645 ? 102.464 155.217 121.765 1.00 100.26 ? 661 CYS A CA  1 
ATOM 1550 C C   . CYS A 1 645 ? 101.652 156.478 121.497 1.00 101.14 ? 661 CYS A C   1 
ATOM 1551 O O   . CYS A 1 645 ? 101.229 156.742 120.370 1.00 101.15 ? 661 CYS A O   1 
ATOM 1552 C CB  . CYS A 1 645 ? 103.462 154.951 120.644 1.00 99.92  ? 661 CYS A CB  1 
ATOM 1553 S SG  . CYS A 1 645 ? 104.521 153.516 120.927 1.00 105.68 ? 661 CYS A SG  1 
ATOM 1554 N N   . MET A 1 646 ? 101.439 157.270 122.547 1.00 102.22 ? 662 MET A N   1 
ATOM 1555 C CA  . MET A 1 646 ? 100.735 158.538 122.428 1.00 100.48 ? 662 MET A CA  1 
ATOM 1556 C C   . MET A 1 646 ? 101.207 159.470 123.533 1.00 102.14 ? 662 MET A C   1 
ATOM 1557 O O   . MET A 1 646 ? 101.793 159.032 124.527 1.00 106.15 ? 662 MET A O   1 
ATOM 1558 C CB  . MET A 1 646 ? 99.214  158.354 122.502 1.00 100.68 ? 662 MET A CB  1 
ATOM 1559 C CG  . MET A 1 646 ? 98.635  157.529 121.365 1.00 101.58 ? 662 MET A CG  1 
ATOM 1560 S SD  . MET A 1 646 ? 96.837  157.613 121.278 1.00 109.71 ? 662 MET A SD  1 
ATOM 1561 C CE  . MET A 1 646 ? 96.598  159.338 120.857 1.00 103.05 ? 662 MET A CE  1 
ATOM 1562 N N   . HIS A 1 647 ? 100.952 160.767 123.346 1.00 97.92  ? 663 HIS A N   1 
ATOM 1563 C CA  . HIS A 1 647 ? 101.368 161.759 124.331 1.00 98.81  ? 663 HIS A CA  1 
ATOM 1564 C C   . HIS A 1 647 ? 100.225 162.125 125.271 1.00 98.75  ? 663 HIS A C   1 
ATOM 1565 O O   . HIS A 1 647 ? 100.355 162.004 126.494 1.00 97.20  ? 663 HIS A O   1 
ATOM 1566 C CB  . HIS A 1 647 ? 101.897 163.008 123.623 1.00 98.99  ? 663 HIS A CB  1 
ATOM 1567 C CG  . HIS A 1 647 ? 102.132 164.167 124.541 1.00 97.93  ? 663 HIS A CG  1 
ATOM 1568 N ND1 . HIS A 1 647 ? 102.713 164.027 125.783 1.00 96.58  ? 663 HIS A ND1 1 
ATOM 1569 C CD2 . HIS A 1 647 ? 101.865 165.487 124.397 1.00 98.61  ? 663 HIS A CD2 1 
ATOM 1570 C CE1 . HIS A 1 647 ? 102.791 165.210 126.366 1.00 96.82  ? 663 HIS A CE1 1 
ATOM 1571 N NE2 . HIS A 1 647 ? 102.285 166.113 125.546 1.00 98.35  ? 663 HIS A NE2 1 
ATOM 1572 N N   . ASP A 1 648 ? 99.101  162.571 124.719 1.00 107.11 ? 664 ASP A N   1 
ATOM 1573 C CA  . ASP A 1 648 ? 97.971  162.988 125.536 1.00 106.42 ? 664 ASP A CA  1 
ATOM 1574 C C   . ASP A 1 648 ? 97.218  161.777 126.072 1.00 106.15 ? 664 ASP A C   1 
ATOM 1575 O O   . ASP A 1 648 ? 97.171  160.720 125.437 1.00 106.97 ? 664 ASP A O   1 
ATOM 1576 C CB  . ASP A 1 648 ? 97.024  163.873 124.725 1.00 108.15 ? 664 ASP A CB  1 
ATOM 1577 C CG  . ASP A 1 648 ? 97.690  165.145 124.236 1.00 108.56 ? 664 ASP A CG  1 
ATOM 1578 O OD1 . ASP A 1 648 ? 98.616  165.633 124.917 1.00 109.06 ? 664 ASP A OD1 1 
ATOM 1579 O OD2 . ASP A 1 648 ? 97.287  165.656 123.171 1.00 105.54 ? 664 ASP A OD2 1 
ATOM 1580 N N   . SER A 1 649 ? 96.628  161.941 127.258 1.00 102.48 ? 665 SER A N   1 
ATOM 1581 C CA  . SER A 1 649 ? 95.826  160.869 127.837 1.00 103.60 ? 665 SER A CA  1 
ATOM 1582 C C   . SER A 1 649 ? 94.594  160.579 126.990 1.00 104.78 ? 665 SER A C   1 
ATOM 1583 O O   . SER A 1 649 ? 94.165  159.423 126.893 1.00 102.02 ? 665 SER A O   1 
ATOM 1584 C CB  . SER A 1 649 ? 95.413  161.234 129.262 1.00 101.08 ? 665 SER A CB  1 
ATOM 1585 O OG  . SER A 1 649 ? 94.639  160.202 129.849 1.00 102.93 ? 665 SER A OG  1 
ATOM 1586 N N   . THR A 1 650 ? 94.018  161.605 126.372 1.00 110.62 ? 666 THR A N   1 
ATOM 1587 C CA  . THR A 1 650 ? 92.866  161.461 125.492 1.00 108.90 ? 666 THR A CA  1 
ATOM 1588 C C   . THR A 1 650 ? 93.346  161.468 124.048 1.00 109.56 ? 666 THR A C   1 
ATOM 1589 O O   . THR A 1 650 ? 94.195  162.285 123.674 1.00 108.82 ? 666 THR A O   1 
ATOM 1590 C CB  . THR A 1 650 ? 91.843  162.578 125.725 1.00 109.38 ? 666 THR A CB  1 
ATOM 1591 O OG1 . THR A 1 650 ? 90.765  162.449 124.788 1.00 109.67 ? 666 THR A OG1 1 
ATOM 1592 C CG2 . THR A 1 650 ? 92.484  163.957 125.578 1.00 107.41 ? 666 THR A CG2 1 
ATOM 1593 N N   . ILE A 1 651 ? 92.805  160.551 123.241 1.00 111.45 ? 667 ILE A N   1 
ATOM 1594 C CA  . ILE A 1 651 ? 93.289  160.366 121.874 1.00 112.09 ? 667 ILE A CA  1 
ATOM 1595 C C   . ILE A 1 651 ? 92.659  161.325 120.878 1.00 112.48 ? 667 ILE A C   1 
ATOM 1596 O O   . ILE A 1 651 ? 93.065  161.337 119.709 1.00 112.53 ? 667 ILE A O   1 
ATOM 1597 C CB  . ILE A 1 651 ? 93.039  158.916 121.415 1.00 110.56 ? 667 ILE A CB  1 
ATOM 1598 C CG1 . ILE A 1 651 ? 91.540  158.651 121.243 1.00 110.29 ? 667 ILE A CG1 1 
ATOM 1599 C CG2 . ILE A 1 651 ? 93.625  157.940 122.419 1.00 109.41 ? 667 ILE A CG2 1 
ATOM 1600 C CD1 . ILE A 1 651 ? 91.213  157.217 120.873 1.00 108.02 ? 667 ILE A CD1 1 
ATOM 1601 N N   . ASP A 1 652 ? 91.680  162.128 121.298 1.00 112.66 ? 668 ASP A N   1 
ATOM 1602 C CA  . ASP A 1 652 ? 91.004  163.025 120.368 1.00 111.50 ? 668 ASP A CA  1 
ATOM 1603 C C   . ASP A 1 652 ? 91.943  164.063 119.767 1.00 109.34 ? 668 ASP A C   1 
ATOM 1604 O O   . ASP A 1 652 ? 91.803  164.395 118.586 1.00 110.18 ? 668 ASP A O   1 
ATOM 1605 C CB  . ASP A 1 652 ? 89.839  163.725 121.069 1.00 111.61 ? 668 ASP A CB  1 
ATOM 1606 C CG  . ASP A 1 652 ? 90.288  164.570 122.244 1.00 112.47 ? 668 ASP A CG  1 
ATOM 1607 O OD1 . ASP A 1 652 ? 91.319  164.231 122.861 1.00 110.08 ? 668 ASP A OD1 1 
ATOM 1608 O OD2 . ASP A 1 652 ? 89.611  165.574 122.551 1.00 112.12 ? 668 ASP A OD2 1 
ATOM 1609 N N   . ARG A 1 653 ? 92.894  164.582 120.546 1.00 102.38 ? 669 ARG A N   1 
ATOM 1610 C CA  . ARG A 1 653 ? 93.778  165.623 120.035 1.00 103.60 ? 669 ARG A CA  1 
ATOM 1611 C C   . ARG A 1 653 ? 94.638  165.112 118.884 1.00 103.18 ? 669 ARG A C   1 
ATOM 1612 O O   . ARG A 1 653 ? 94.833  165.821 117.890 1.00 103.06 ? 669 ARG A O   1 
ATOM 1613 C CB  . ARG A 1 653 ? 94.658  166.158 121.167 1.00 103.11 ? 669 ARG A CB  1 
ATOM 1614 C CG  . ARG A 1 653 ? 95.307  167.511 120.887 1.00 99.54  ? 669 ARG A CG  1 
ATOM 1615 C CD  . ARG A 1 653 ? 96.617  167.386 120.122 1.00 100.26 ? 669 ARG A CD  1 
ATOM 1616 N NE  . ARG A 1 653 ? 97.611  166.604 120.847 1.00 104.75 ? 669 ARG A NE  1 
ATOM 1617 C CZ  . ARG A 1 653 ? 98.846  166.381 120.420 1.00 103.84 ? 669 ARG A CZ  1 
ATOM 1618 N NH1 . ARG A 1 653 ? 99.277  166.867 119.267 1.00 101.64 ? 669 ARG A NH1 1 
ATOM 1619 N NH2 . ARG A 1 653 ? 99.670  165.653 121.168 1.00 102.82 ? 669 ARG A NH2 1 
ATOM 1620 N N   . THR A 1 654 ? 95.150  163.885 118.993 1.00 113.00 ? 670 THR A N   1 
ATOM 1621 C CA  . THR A 1 654 ? 96.098  163.357 118.021 1.00 113.03 ? 670 THR A CA  1 
ATOM 1622 C C   . THR A 1 654 ? 95.470  162.414 117.005 1.00 111.88 ? 670 THR A C   1 
ATOM 1623 O O   . THR A 1 654 ? 96.039  162.229 115.922 1.00 111.53 ? 670 THR A O   1 
ATOM 1624 C CB  . THR A 1 654 ? 97.235  162.619 118.740 1.00 113.68 ? 670 THR A CB  1 
ATOM 1625 O OG1 . THR A 1 654 ? 97.862  163.501 119.680 1.00 115.17 ? 670 THR A OG1 1 
ATOM 1626 C CG2 . THR A 1 654 ? 98.275  162.122 117.745 1.00 111.56 ? 670 THR A CG2 1 
ATOM 1627 N N   . THR A 1 655 ? 94.320  161.818 117.311 1.00 113.60 ? 671 THR A N   1 
ATOM 1628 C CA  . THR A 1 655 ? 93.716  160.811 116.453 1.00 114.61 ? 671 THR A CA  1 
ATOM 1629 C C   . THR A 1 655 ? 92.246  161.132 116.223 1.00 115.47 ? 671 THR A C   1 
ATOM 1630 O O   . THR A 1 655 ? 91.633  161.916 116.953 1.00 114.14 ? 671 THR A O   1 
ATOM 1631 C CB  . THR A 1 655 ? 93.845  159.406 117.058 1.00 113.27 ? 671 THR A CB  1 
ATOM 1632 O OG1 . THR A 1 655 ? 93.052  159.323 118.248 1.00 115.42 ? 671 THR A OG1 1 
ATOM 1633 C CG2 . THR A 1 655 ? 95.295  159.102 117.397 1.00 111.52 ? 671 THR A CG2 1 
ATOM 1634 N N   . THR A 1 656 ? 91.685  160.505 115.186 1.00 117.29 ? 672 THR A N   1 
ATOM 1635 C CA  . THR A 1 656 ? 90.280  160.696 114.847 1.00 116.38 ? 672 THR A CA  1 
ATOM 1636 C C   . THR A 1 656 ? 89.340  160.170 115.923 1.00 116.16 ? 672 THR A C   1 
ATOM 1637 O O   . THR A 1 656 ? 88.167  160.558 115.939 1.00 116.05 ? 672 THR A O   1 
ATOM 1638 C CB  . THR A 1 656 ? 89.964  160.008 113.518 1.00 115.51 ? 672 THR A CB  1 
ATOM 1639 O OG1 . THR A 1 656 ? 90.266  158.610 113.617 1.00 116.69 ? 672 THR A OG1 1 
ATOM 1640 C CG2 . THR A 1 656 ? 90.778  160.623 112.389 1.00 112.23 ? 672 THR A CG2 1 
ATOM 1641 N N   . GLY A 1 657 ? 89.818  159.306 116.813 1.00 118.77 ? 673 GLY A N   1 
ATOM 1642 C CA  . GLY A 1 657 ? 88.997  158.773 117.877 1.00 118.36 ? 673 GLY A CA  1 
ATOM 1643 C C   . GLY A 1 657 ? 88.805  159.777 118.998 1.00 119.18 ? 673 GLY A C   1 
ATOM 1644 O O   . GLY A 1 657 ? 89.055  160.976 118.859 1.00 117.64 ? 673 GLY A O   1 
ATOM 1645 N N   . THR A 1 658 ? 88.335  159.266 120.133 1.00 119.65 ? 674 THR A N   1 
ATOM 1646 C CA  . THR A 1 658 ? 88.096  160.106 121.297 1.00 118.64 ? 674 THR A CA  1 
ATOM 1647 C C   . THR A 1 658 ? 88.078  159.232 122.541 1.00 118.78 ? 674 THR A C   1 
ATOM 1648 O O   . THR A 1 658 ? 87.971  158.006 122.461 1.00 118.32 ? 674 THR A O   1 
ATOM 1649 C CB  . THR A 1 658 ? 86.783  160.889 121.171 1.00 117.72 ? 674 THR A CB  1 
ATOM 1650 O OG1 . THR A 1 658 ? 86.580  161.680 122.349 1.00 118.97 ? 674 THR A OG1 1 
ATOM 1651 C CG2 . THR A 1 658 ? 85.601  159.943 120.986 1.00 116.60 ? 674 THR A CG2 1 
ATOM 1652 N N   . GLY A 1 659 ? 88.187  159.885 123.695 1.00 114.41 ? 675 GLY A N   1 
ATOM 1653 C CA  . GLY A 1 659 ? 88.170  159.203 124.969 1.00 114.38 ? 675 GLY A CA  1 
ATOM 1654 C C   . GLY A 1 659 ? 89.560  158.835 125.457 1.00 114.09 ? 675 GLY A C   1 
ATOM 1655 O O   . GLY A 1 659 ? 90.564  158.950 124.751 1.00 113.26 ? 675 GLY A O   1 
ATOM 1656 N N   . LYS A 1 660 ? 89.607  158.381 126.706 1.00 110.51 ? 676 LYS A N   1 
ATOM 1657 C CA  . LYS A 1 660 ? 90.866  157.973 127.308 1.00 109.99 ? 676 LYS A CA  1 
ATOM 1658 C C   . LYS A 1 660 ? 91.409  156.727 126.618 1.00 110.03 ? 676 LYS A C   1 
ATOM 1659 O O   . LYS A 1 660 ? 90.659  155.905 126.085 1.00 110.63 ? 676 LYS A O   1 
ATOM 1660 C CB  . LYS A 1 660 ? 90.684  157.699 128.801 1.00 110.44 ? 676 LYS A CB  1 
ATOM 1661 C CG  . LYS A 1 660 ? 90.095  158.860 129.588 1.00 109.09 ? 676 LYS A CG  1 
ATOM 1662 C CD  . LYS A 1 660 ? 91.058  160.031 129.670 1.00 110.15 ? 676 LYS A CD  1 
ATOM 1663 C CE  . LYS A 1 660 ? 90.496  161.149 130.534 1.00 109.91 ? 676 LYS A CE  1 
ATOM 1664 N NZ  . LYS A 1 660 ? 91.462  162.270 130.704 1.00 110.14 ? 676 LYS A NZ  1 
ATOM 1665 N N   . VAL A 1 661 ? 92.737  156.594 126.633 1.00 102.59 ? 677 VAL A N   1 
ATOM 1666 C CA  . VAL A 1 661 ? 93.372  155.434 126.015 1.00 101.23 ? 677 VAL A CA  1 
ATOM 1667 C C   . VAL A 1 661 ? 92.957  154.154 126.726 1.00 101.54 ? 677 VAL A C   1 
ATOM 1668 O O   . VAL A 1 661 ? 92.808  153.102 126.093 1.00 101.50 ? 677 VAL A O   1 
ATOM 1669 C CB  . VAL A 1 661 ? 94.905  155.600 126.013 1.00 99.81  ? 677 VAL A CB  1 
ATOM 1670 C CG1 . VAL A 1 661 ? 95.573  154.338 125.484 1.00 98.97  ? 677 VAL A CG1 1 
ATOM 1671 C CG2 . VAL A 1 661 ? 95.310  156.819 125.190 1.00 98.45  ? 677 VAL A CG2 1 
ATOM 1672 N N   . GLY A 1 662 ? 92.767  154.216 128.044 1.00 106.99 ? 678 GLY A N   1 
ATOM 1673 C CA  . GLY A 1 662 ? 92.398  153.038 128.808 1.00 108.43 ? 678 GLY A CA  1 
ATOM 1674 C C   . GLY A 1 662 ? 90.935  152.658 128.717 1.00 107.35 ? 678 GLY A C   1 
ATOM 1675 O O   . GLY A 1 662 ? 90.544  151.640 129.298 1.00 103.71 ? 678 GLY A O   1 
ATOM 1676 N N   . ASP A 1 663 ? 90.122  153.445 128.009 1.00 112.24 ? 679 ASP A N   1 
ATOM 1677 C CA  . ASP A 1 663 ? 88.699  153.145 127.908 1.00 112.34 ? 679 ASP A CA  1 
ATOM 1678 C C   . ASP A 1 663 ? 88.429  151.893 127.083 1.00 113.37 ? 679 ASP A C   1 
ATOM 1679 O O   . ASP A 1 663 ? 87.455  151.181 127.352 1.00 114.42 ? 679 ASP A O   1 
ATOM 1680 C CB  . ASP A 1 663 ? 87.952  154.332 127.299 1.00 113.29 ? 679 ASP A CB  1 
ATOM 1681 C CG  . ASP A 1 663 ? 87.936  155.541 128.211 1.00 115.36 ? 679 ASP A CG  1 
ATOM 1682 O OD1 . ASP A 1 663 ? 87.971  155.357 129.446 1.00 116.32 ? 679 ASP A OD1 1 
ATOM 1683 O OD2 . ASP A 1 663 ? 87.887  156.676 127.693 1.00 115.43 ? 679 ASP A OD2 1 
ATOM 1684 N N   . MET A 1 664 ? 89.262  151.610 126.083 1.00 110.38 ? 680 MET A N   1 
ATOM 1685 C CA  . MET A 1 664 ? 89.011  150.507 125.167 1.00 111.83 ? 680 MET A CA  1 
ATOM 1686 C C   . MET A 1 664 ? 90.303  149.741 124.920 1.00 111.13 ? 680 MET A C   1 
ATOM 1687 O O   . MET A 1 664 ? 91.394  150.179 125.292 1.00 110.41 ? 680 MET A O   1 
ATOM 1688 C CB  . MET A 1 664 ? 88.425  151.008 123.841 1.00 112.94 ? 680 MET A CB  1 
ATOM 1689 C CG  . MET A 1 664 ? 87.205  151.901 124.015 1.00 113.53 ? 680 MET A CG  1 
ATOM 1690 S SD  . MET A 1 664 ? 86.358  152.267 122.467 1.00 112.49 ? 680 MET A SD  1 
ATOM 1691 C CE  . MET A 1 664 ? 85.661  150.663 122.076 1.00 110.74 ? 680 MET A CE  1 
ATOM 1692 N N   . THR A 1 665 ? 90.159  148.580 124.286 1.00 109.58 ? 681 THR A N   1 
ATOM 1693 C CA  . THR A 1 665 ? 91.285  147.688 124.058 1.00 108.21 ? 681 THR A CA  1 
ATOM 1694 C C   . THR A 1 665 ? 92.208  148.236 122.972 1.00 107.89 ? 681 THR A C   1 
ATOM 1695 O O   . THR A 1 665 ? 91.849  149.124 122.194 1.00 108.51 ? 681 THR A O   1 
ATOM 1696 C CB  . THR A 1 665 ? 90.794  146.295 123.661 1.00 109.54 ? 681 THR A CB  1 
ATOM 1697 O OG1 . THR A 1 665 ? 90.040  146.377 122.445 1.00 110.14 ? 681 THR A OG1 1 
ATOM 1698 C CG2 . THR A 1 665 ? 89.920  145.702 124.758 1.00 110.21 ? 681 THR A CG2 1 
ATOM 1699 N N   . LEU A 1 666 ? 93.422  147.681 122.929 1.00 103.48 ? 682 LEU A N   1 
ATOM 1700 C CA  . LEU A 1 666 ? 94.409  148.120 121.947 1.00 103.45 ? 682 LEU A CA  1 
ATOM 1701 C C   . LEU A 1 666 ? 93.945  147.834 120.525 1.00 102.73 ? 682 LEU A C   1 
ATOM 1702 O O   . LEU A 1 666 ? 94.131  148.662 119.626 1.00 101.08 ? 682 LEU A O   1 
ATOM 1703 C CB  . LEU A 1 666 ? 95.750  147.436 122.217 1.00 102.46 ? 682 LEU A CB  1 
ATOM 1704 C CG  . LEU A 1 666 ? 96.837  147.622 121.154 1.00 100.32 ? 682 LEU A CG  1 
ATOM 1705 C CD1 . LEU A 1 666 ? 97.133  149.097 120.933 1.00 97.49  ? 682 LEU A CD1 1 
ATOM 1706 C CD2 . LEU A 1 666 ? 98.099  146.871 121.549 1.00 99.26  ? 682 LEU A CD2 1 
ATOM 1707 N N   . SER A 1 667 ? 93.352  146.660 120.297 1.00 108.65 ? 683 SER A N   1 
ATOM 1708 C CA  . SER A 1 667 ? 92.968  146.279 118.941 1.00 109.84 ? 683 SER A CA  1 
ATOM 1709 C C   . SER A 1 667 ? 91.949  147.248 118.356 1.00 110.82 ? 683 SER A C   1 
ATOM 1710 O O   . SER A 1 667 ? 92.096  147.697 117.212 1.00 108.60 ? 683 SER A O   1 
ATOM 1711 C CB  . SER A 1 667 ? 92.411  144.855 118.937 1.00 107.81 ? 683 SER A CB  1 
ATOM 1712 O OG  . SER A 1 667 ? 92.052  144.457 117.625 1.00 106.36 ? 683 SER A OG  1 
ATOM 1713 N N   . TYR A 1 668 ? 90.911  147.585 119.123 1.00 113.64 ? 684 TYR A N   1 
ATOM 1714 C CA  . TYR A 1 668 ? 89.889  148.501 118.627 1.00 111.57 ? 684 TYR A CA  1 
ATOM 1715 C C   . TYR A 1 668 ? 90.485  149.872 118.336 1.00 111.88 ? 684 TYR A C   1 
ATOM 1716 O O   . TYR A 1 668 ? 90.183  150.491 117.310 1.00 114.11 ? 684 TYR A O   1 
ATOM 1717 C CB  . TYR A 1 668 ? 88.748  148.613 119.641 1.00 110.96 ? 684 TYR A CB  1 
ATOM 1718 C CG  . TYR A 1 668 ? 87.665  149.587 119.230 1.00 113.26 ? 684 TYR A CG  1 
ATOM 1719 C CD1 . TYR A 1 668 ? 87.759  150.936 119.550 1.00 112.86 ? 684 TYR A CD1 1 
ATOM 1720 C CD2 . TYR A 1 668 ? 86.549  149.159 118.523 1.00 113.72 ? 684 TYR A CD2 1 
ATOM 1721 C CE1 . TYR A 1 668 ? 86.774  151.829 119.175 1.00 113.30 ? 684 TYR A CE1 1 
ATOM 1722 C CE2 . TYR A 1 668 ? 85.558  150.046 118.145 1.00 114.05 ? 684 TYR A CE2 1 
ATOM 1723 C CZ  . TYR A 1 668 ? 85.676  151.379 118.474 1.00 114.27 ? 684 TYR A CZ  1 
ATOM 1724 O OH  . TYR A 1 668 ? 84.695  152.268 118.102 1.00 112.99 ? 684 TYR A OH  1 
ATOM 1725 N N   . ILE A 1 669 ? 91.340  150.365 119.233 1.00 108.11 ? 685 ILE A N   1 
ATOM 1726 C CA  . ILE A 1 669 ? 91.936  151.684 119.044 1.00 109.24 ? 685 ILE A CA  1 
ATOM 1727 C C   . ILE A 1 669 ? 92.798  151.698 117.788 1.00 107.79 ? 685 ILE A C   1 
ATOM 1728 O O   . ILE A 1 669 ? 92.760  152.647 116.996 1.00 108.70 ? 685 ILE A O   1 
ATOM 1729 C CB  . ILE A 1 669 ? 92.746  152.088 120.289 1.00 109.06 ? 685 ILE A CB  1 
ATOM 1730 C CG1 . ILE A 1 669 ? 91.820  152.215 121.502 1.00 109.26 ? 685 ILE A CG1 1 
ATOM 1731 C CG2 . ILE A 1 669 ? 93.489  153.395 120.037 1.00 106.98 ? 685 ILE A CG2 1 
ATOM 1732 C CD1 . ILE A 1 669 ? 92.550  152.330 122.823 1.00 108.04 ? 685 ILE A CD1 1 
ATOM 1733 N N   . GLN A 1 670 ? 93.590  150.643 117.586 1.00 96.10  ? 686 GLN A N   1 
ATOM 1734 C CA  . GLN A 1 670 ? 94.505  150.607 116.453 1.00 95.97  ? 686 GLN A CA  1 
ATOM 1735 C C   . GLN A 1 670 ? 93.797  150.316 115.135 1.00 98.49  ? 686 GLN A C   1 
ATOM 1736 O O   . GLN A 1 670 ? 94.340  150.643 114.074 1.00 98.84  ? 686 GLN A O   1 
ATOM 1737 C CB  . GLN A 1 670 ? 95.594  149.561 116.697 1.00 95.55  ? 686 GLN A CB  1 
ATOM 1738 C CG  . GLN A 1 670 ? 96.724  149.597 115.683 1.00 97.21  ? 686 GLN A CG  1 
ATOM 1739 C CD  . GLN A 1 670 ? 97.854  148.651 116.036 1.00 94.90  ? 686 GLN A CD  1 
ATOM 1740 O OE1 . GLN A 1 670 ? 97.721  147.808 116.924 1.00 93.73  ? 686 GLN A OE1 1 
ATOM 1741 N NE2 . GLN A 1 670 ? 98.978  148.789 115.343 1.00 95.61  ? 686 GLN A NE2 1 
ATOM 1742 N N   . THR A 1 671 ? 92.606  149.717 115.171 1.00 103.48 ? 687 THR A N   1 
ATOM 1743 C CA  . THR A 1 671 ? 91.885  149.371 113.951 1.00 102.77 ? 687 THR A CA  1 
ATOM 1744 C C   . THR A 1 671 ? 90.881  150.441 113.533 1.00 104.67 ? 687 THR A C   1 
ATOM 1745 O O   . THR A 1 671 ? 90.892  150.884 112.381 1.00 102.40 ? 687 THR A O   1 
ATOM 1746 C CB  . THR A 1 671 ? 91.159  148.032 114.135 1.00 103.09 ? 687 THR A CB  1 
ATOM 1747 O OG1 . THR A 1 671 ? 92.098  147.024 114.531 1.00 103.25 ? 687 THR A OG1 1 
ATOM 1748 C CG2 . THR A 1 671 ? 90.477  147.603 112.841 1.00 102.04 ? 687 THR A CG2 1 
ATOM 1749 N N   . ASN A 1 672 ? 90.010  150.864 114.449 1.00 111.38 ? 688 ASN A N   1 
ATOM 1750 C CA  . ASN A 1 672 ? 88.934  151.789 114.117 1.00 109.78 ? 688 ASN A CA  1 
ATOM 1751 C C   . ASN A 1 672 ? 89.380  153.244 114.069 1.00 109.94 ? 688 ASN A C   1 
ATOM 1752 O O   . ASN A 1 672 ? 88.610  154.091 113.604 1.00 109.67 ? 688 ASN A O   1 
ATOM 1753 C CB  . ASN A 1 672 ? 87.795  151.647 115.131 1.00 107.15 ? 688 ASN A CB  1 
ATOM 1754 C CG  . ASN A 1 672 ? 87.207  150.250 115.156 1.00 108.01 ? 688 ASN A CG  1 
ATOM 1755 O OD1 . ASN A 1 672 ? 87.765  149.342 115.772 1.00 107.95 ? 688 ASN A OD1 1 
ATOM 1756 N ND2 . ASN A 1 672 ? 86.072  150.072 114.490 1.00 108.45 ? 688 ASN A ND2 1 
ATOM 1757 N N   . PHE A 1 673 ? 90.590  153.558 114.530 1.00 112.48 ? 689 PHE A N   1 
ATOM 1758 C CA  . PHE A 1 673 ? 91.058  154.933 114.607 1.00 111.14 ? 689 PHE A CA  1 
ATOM 1759 C C   . PHE A 1 673 ? 92.411  155.065 113.922 1.00 110.55 ? 689 PHE A C   1 
ATOM 1760 O O   . PHE A 1 673 ? 93.179  154.105 113.819 1.00 109.97 ? 689 PHE A O   1 
ATOM 1761 C CB  . PHE A 1 673 ? 91.172  155.411 116.064 1.00 112.11 ? 689 PHE A CB  1 
ATOM 1762 C CG  . PHE A 1 673 ? 89.872  155.387 116.819 1.00 113.90 ? 689 PHE A CG  1 
ATOM 1763 C CD1 . PHE A 1 673 ? 88.673  155.647 116.177 1.00 113.56 ? 689 PHE A CD1 1 
ATOM 1764 C CD2 . PHE A 1 673 ? 89.850  155.104 118.175 1.00 113.88 ? 689 PHE A CD2 1 
ATOM 1765 C CE1 . PHE A 1 673 ? 87.479  155.626 116.870 1.00 113.10 ? 689 PHE A CE1 1 
ATOM 1766 C CE2 . PHE A 1 673 ? 88.657  155.081 118.874 1.00 114.67 ? 689 PHE A CE2 1 
ATOM 1767 C CZ  . PHE A 1 673 ? 87.471  155.342 118.220 1.00 113.65 ? 689 PHE A CZ  1 
ATOM 1768 N N   . THR A 1 674 ? 92.688  156.280 113.455 1.00 114.71 ? 690 THR A N   1 
ATOM 1769 C CA  . THR A 1 674 ? 93.958  156.620 112.832 1.00 115.28 ? 690 THR A CA  1 
ATOM 1770 C C   . THR A 1 674 ? 94.264  158.081 113.127 1.00 116.41 ? 690 THR A C   1 
ATOM 1771 O O   . THR A 1 674 ? 93.385  158.857 113.515 1.00 115.78 ? 690 THR A O   1 
ATOM 1772 C CB  . THR A 1 674 ? 93.936  156.373 111.317 1.00 114.80 ? 690 THR A CB  1 
ATOM 1773 O OG1 . THR A 1 674 ? 92.834  157.078 110.730 1.00 115.04 ? 690 THR A OG1 1 
ATOM 1774 C CG2 . THR A 1 674 ? 93.810  154.886 111.012 1.00 113.95 ? 690 THR A CG2 1 
ATOM 1775 N N   . SER A 1 675 ? 95.527  158.455 112.944 1.00 115.30 ? 691 SER A N   1 
ATOM 1776 C CA  . SER A 1 675 ? 95.944  159.823 113.204 1.00 114.40 ? 691 SER A CA  1 
ATOM 1777 C C   . SER A 1 675 ? 95.214  160.787 112.270 1.00 114.69 ? 691 SER A C   1 
ATOM 1778 O O   . SER A 1 675 ? 94.586  160.394 111.284 1.00 112.16 ? 691 SER A O   1 
ATOM 1779 C CB  . SER A 1 675 ? 97.455  159.963 113.030 1.00 112.24 ? 691 SER A CB  1 
ATOM 1780 O OG  . SER A 1 675 ? 97.834  159.723 111.686 1.00 111.89 ? 691 SER A OG  1 
ATOM 1781 N N   . LEU A 1 676 ? 95.305  162.078 112.599 1.00 115.46 ? 692 LEU A N   1 
ATOM 1782 C CA  . LEU A 1 676 ? 94.671  163.096 111.770 1.00 114.21 ? 692 LEU A CA  1 
ATOM 1783 C C   . LEU A 1 676 ? 95.226  163.102 110.352 1.00 114.17 ? 692 LEU A C   1 
ATOM 1784 O O   . LEU A 1 676 ? 94.540  163.559 109.431 1.00 114.03 ? 692 LEU A O   1 
ATOM 1785 C CB  . LEU A 1 676 ? 94.849  164.476 112.406 1.00 112.42 ? 692 LEU A CB  1 
ATOM 1786 C CG  . LEU A 1 676 ? 94.246  164.648 113.802 1.00 112.65 ? 692 LEU A CG  1 
ATOM 1787 C CD1 . LEU A 1 676 ? 94.532  166.043 114.336 1.00 111.60 ? 692 LEU A CD1 1 
ATOM 1788 C CD2 . LEU A 1 676 ? 92.748  164.374 113.789 1.00 112.98 ? 692 LEU A CD2 1 
ATOM 1789 N N   . ASN A 1 677 ? 96.446  162.607 110.157 1.00 110.19 ? 693 ASN A N   1 
ATOM 1790 C CA  . ASN A 1 677 ? 97.037  162.471 108.834 1.00 110.04 ? 693 ASN A CA  1 
ATOM 1791 C C   . ASN A 1 677 ? 96.755  161.112 108.206 1.00 110.49 ? 693 ASN A C   1 
ATOM 1792 O O   . ASN A 1 677 ? 97.247  160.836 107.107 1.00 110.78 ? 693 ASN A O   1 
ATOM 1793 C CB  . ASN A 1 677 ? 98.548  162.701 108.908 1.00 110.38 ? 693 ASN A CB  1 
ATOM 1794 C CG  . ASN A 1 677 ? 98.902  164.098 109.377 1.00 111.38 ? 693 ASN A CG  1 
ATOM 1795 O OD1 . ASN A 1 677 ? 98.084  164.786 109.988 1.00 110.91 ? 693 ASN A OD1 1 
ATOM 1796 N ND2 . ASN A 1 677 ? 100.126 164.525 109.091 1.00 109.50 ? 693 ASN A ND2 1 
ATOM 1797 N N   . GLY A 1 678 ? 95.982  160.261 108.877 1.00 108.56 ? 694 GLY A N   1 
ATOM 1798 C CA  . GLY A 1 678 ? 95.664  158.948 108.358 1.00 108.18 ? 694 GLY A CA  1 
ATOM 1799 C C   . GLY A 1 678 ? 96.710  157.889 108.614 1.00 108.54 ? 694 GLY A C   1 
ATOM 1800 O O   . GLY A 1 678 ? 96.554  156.760 108.134 1.00 104.66 ? 694 GLY A O   1 
ATOM 1801 N N   . GLU A 1 679 ? 97.768  158.208 109.352 1.00 110.03 ? 695 GLU A N   1 
ATOM 1802 C CA  . GLU A 1 679 ? 98.811  157.237 109.630 1.00 107.97 ? 695 GLU A CA  1 
ATOM 1803 C C   . GLU A 1 679 ? 98.364  156.269 110.721 1.00 109.03 ? 695 GLU A C   1 
ATOM 1804 O O   . GLU A 1 679 ? 97.503  156.596 111.542 1.00 106.81 ? 695 GLU A O   1 
ATOM 1805 C CB  . GLU A 1 679 ? 100.092 157.946 110.056 1.00 106.22 ? 695 GLU A CB  1 
ATOM 1806 C CG  . GLU A 1 679 ? 100.644 158.914 109.020 1.00 106.28 ? 695 GLU A CG  1 
ATOM 1807 C CD  . GLU A 1 679 ? 101.107 158.217 107.756 1.00 106.23 ? 695 GLU A CD  1 
ATOM 1808 O OE1 . GLU A 1 679 ? 101.185 156.970 107.756 1.00 105.99 ? 695 GLU A OE1 1 
ATOM 1809 O OE2 . GLU A 1 679 ? 101.393 158.916 106.761 1.00 105.38 ? 695 GLU A OE2 1 
ATOM 1810 N N   . PRO A 1 680 ? 98.934  155.064 110.753 1.00 111.18 ? 696 PRO A N   1 
ATOM 1811 C CA  . PRO A 1 680 ? 98.577  154.117 111.816 1.00 110.01 ? 696 PRO A CA  1 
ATOM 1812 C C   . PRO A 1 680 ? 99.007  154.627 113.182 1.00 106.21 ? 696 PRO A C   1 
ATOM 1813 O O   . PRO A 1 680 ? 99.915  155.451 113.306 1.00 105.04 ? 696 PRO A O   1 
ATOM 1814 C CB  . PRO A 1 680 ? 99.339  152.842 111.432 1.00 108.04 ? 696 PRO A CB  1 
ATOM 1815 C CG  . PRO A 1 680 ? 99.655  152.989 109.990 1.00 107.48 ? 696 PRO A CG  1 
ATOM 1816 C CD  . PRO A 1 680 ? 99.823  154.454 109.750 1.00 107.10 ? 696 PRO A CD  1 
ATOM 1817 N N   . ILE A 1 681 ? 98.326  154.136 114.213 1.00 100.86 ? 697 ILE A N   1 
ATOM 1818 C CA  . ILE A 1 681 ? 98.682  154.420 115.600 1.00 101.92 ? 697 ILE A CA  1 
ATOM 1819 C C   . ILE A 1 681 ? 99.519  153.247 116.104 1.00 101.75 ? 697 ILE A C   1 
ATOM 1820 O O   . ILE A 1 681 ? 98.949  152.242 116.557 1.00 102.42 ? 697 ILE A O   1 
ATOM 1821 C CB  . ILE A 1 681 ? 97.435  154.631 116.471 1.00 103.17 ? 697 ILE A CB  1 
ATOM 1822 C CG1 . ILE A 1 681 ? 96.516  155.683 115.842 1.00 102.34 ? 697 ILE A CG1 1 
ATOM 1823 C CG2 . ILE A 1 681 ? 97.835  155.064 117.876 1.00 103.03 ? 697 ILE A CG2 1 
ATOM 1824 C CD1 . ILE A 1 681 ? 95.161  155.795 116.510 1.00 102.95 ? 697 ILE A CD1 1 
ATOM 1825 N N   . PRO A 1 682 ? 100.848 153.320 116.048 1.00 95.63  ? 698 PRO A N   1 
ATOM 1826 C CA  . PRO A 1 682 ? 101.660 152.147 116.387 1.00 96.32  ? 698 PRO A CA  1 
ATOM 1827 C C   . PRO A 1 682 ? 101.732 151.902 117.886 1.00 96.77  ? 698 PRO A C   1 
ATOM 1828 O O   . PRO A 1 682 ? 101.771 152.836 118.692 1.00 96.30  ? 698 PRO A O   1 
ATOM 1829 C CB  . PRO A 1 682 ? 103.038 152.505 115.819 1.00 92.97  ? 698 PRO A CB  1 
ATOM 1830 C CG  . PRO A 1 682 ? 103.092 153.985 115.921 1.00 95.31  ? 698 PRO A CG  1 
ATOM 1831 C CD  . PRO A 1 682 ? 101.687 154.467 115.654 1.00 94.69  ? 698 PRO A CD  1 
ATOM 1832 N N   . SER A 1 683 ? 101.742 150.623 118.253 1.00 95.20  ? 699 SER A N   1 
ATOM 1833 C CA  . SER A 1 683 ? 102.015 150.237 119.627 1.00 92.48  ? 699 SER A CA  1 
ATOM 1834 C C   . SER A 1 683 ? 103.520 150.103 119.841 1.00 90.99  ? 699 SER A C   1 
ATOM 1835 O O   . SER A 1 683 ? 104.315 150.134 118.897 1.00 90.89  ? 699 SER A O   1 
ATOM 1836 C CB  . SER A 1 683 ? 101.317 148.921 119.969 1.00 92.59  ? 699 SER A CB  1 
ATOM 1837 O OG  . SER A 1 683 ? 101.769 147.870 119.134 1.00 89.51  ? 699 SER A OG  1 
ATOM 1838 N N   . LEU A 1 684 ? 103.911 149.950 121.107 1.00 81.05  ? 700 LEU A N   1 
ATOM 1839 C CA  . LEU A 1 684 ? 105.330 149.822 121.419 1.00 79.73  ? 700 LEU A CA  1 
ATOM 1840 C C   . LEU A 1 684 ? 105.937 148.614 120.718 1.00 83.06  ? 700 LEU A C   1 
ATOM 1841 O O   . LEU A 1 684 ? 107.037 148.699 120.158 1.00 84.42  ? 700 LEU A O   1 
ATOM 1842 C CB  . LEU A 1 684 ? 105.526 149.720 122.932 1.00 79.95  ? 700 LEU A CB  1 
ATOM 1843 C CG  . LEU A 1 684 ? 106.971 149.595 123.422 1.00 82.14  ? 700 LEU A CG  1 
ATOM 1844 C CD1 . LEU A 1 684 ? 107.788 150.808 123.007 1.00 79.70  ? 700 LEU A CD1 1 
ATOM 1845 C CD2 . LEU A 1 684 ? 107.003 149.415 124.931 1.00 79.40  ? 700 LEU A CD2 1 
ATOM 1846 N N   . ASP A 1 685 ? 105.229 147.483 120.728 1.00 86.38  ? 701 ASP A N   1 
ATOM 1847 C CA  . ASP A 1 685 ? 105.747 146.282 120.083 1.00 85.76  ? 701 ASP A CA  1 
ATOM 1848 C C   . ASP A 1 685 ? 105.964 146.508 118.593 1.00 87.57  ? 701 ASP A C   1 
ATOM 1849 O O   . ASP A 1 685 ? 106.965 146.053 118.028 1.00 85.80  ? 701 ASP A O   1 
ATOM 1850 C CB  . ASP A 1 685 ? 104.792 145.112 120.313 1.00 87.12  ? 701 ASP A CB  1 
ATOM 1851 C CG  . ASP A 1 685 ? 105.275 143.830 119.664 1.00 89.11  ? 701 ASP A CG  1 
ATOM 1852 O OD1 . ASP A 1 685 ? 106.270 143.254 120.152 1.00 89.95  ? 701 ASP A OD1 1 
ATOM 1853 O OD2 . ASP A 1 685 ? 104.661 143.399 118.665 1.00 89.02  ? 701 ASP A OD2 1 
ATOM 1854 N N   . ASP A 1 686 ? 105.031 147.201 117.936 1.00 89.79  ? 702 ASP A N   1 
ATOM 1855 C CA  . ASP A 1 686 ? 105.183 147.472 116.510 1.00 88.58  ? 702 ASP A CA  1 
ATOM 1856 C C   . ASP A 1 686 ? 106.430 148.303 116.237 1.00 88.11  ? 702 ASP A C   1 
ATOM 1857 O O   . ASP A 1 686 ? 107.192 148.006 115.308 1.00 85.85  ? 702 ASP A O   1 
ATOM 1858 C CB  . ASP A 1 686 ? 103.939 148.182 115.978 1.00 90.26  ? 702 ASP A CB  1 
ATOM 1859 C CG  . ASP A 1 686 ? 102.686 147.337 116.105 1.00 90.21  ? 702 ASP A CG  1 
ATOM 1860 O OD1 . ASP A 1 686 ? 102.796 146.095 116.038 1.00 89.95  ? 702 ASP A OD1 1 
ATOM 1861 O OD2 . ASP A 1 686 ? 101.592 147.915 116.273 1.00 89.24  ? 702 ASP A OD2 1 
ATOM 1862 N N   . VAL A 1 687 ? 106.658 149.349 117.034 1.00 84.78  ? 703 VAL A N   1 
ATOM 1863 C CA  . VAL A 1 687 ? 107.833 150.192 116.835 1.00 84.99  ? 703 VAL A CA  1 
ATOM 1864 C C   . VAL A 1 687 ? 109.107 149.389 117.062 1.00 84.45  ? 703 VAL A C   1 
ATOM 1865 O O   . VAL A 1 687 ? 110.069 149.484 116.289 1.00 85.61  ? 703 VAL A O   1 
ATOM 1866 C CB  . VAL A 1 687 ? 107.773 151.423 117.757 1.00 83.87  ? 703 VAL A CB  1 
ATOM 1867 C CG1 . VAL A 1 687 ? 109.019 152.282 117.584 1.00 84.11  ? 703 VAL A CG1 1 
ATOM 1868 C CG2 . VAL A 1 687 ? 106.520 152.236 117.473 1.00 84.17  ? 703 VAL A CG2 1 
ATOM 1869 N N   . LEU A 1 688 ? 109.136 148.587 118.129 1.00 77.94  ? 704 LEU A N   1 
ATOM 1870 C CA  . LEU A 1 688 ? 110.325 147.790 118.411 1.00 79.34  ? 704 LEU A CA  1 
ATOM 1871 C C   . LEU A 1 688 ? 110.605 146.801 117.288 1.00 80.78  ? 704 LEU A C   1 
ATOM 1872 O O   . LEU A 1 688 ? 111.762 146.613 116.897 1.00 77.61  ? 704 LEU A O   1 
ATOM 1873 C CB  . LEU A 1 688 ? 110.164 147.056 119.742 1.00 76.98  ? 704 LEU A CB  1 
ATOM 1874 C CG  . LEU A 1 688 ? 110.029 147.937 120.988 1.00 75.03  ? 704 LEU A CG  1 
ATOM 1875 C CD1 . LEU A 1 688 ? 109.907 147.081 122.240 1.00 72.88  ? 704 LEU A CD1 1 
ATOM 1876 C CD2 . LEU A 1 688 ? 111.198 148.902 121.106 1.00 74.34  ? 704 LEU A CD2 1 
ATOM 1877 N N   . ASN A 1 689 ? 109.562 146.160 116.755 1.00 88.99  ? 705 ASN A N   1 
ATOM 1878 C CA  . ASN A 1 689 ? 109.757 145.240 115.640 1.00 88.62  ? 705 ASN A CA  1 
ATOM 1879 C C   . ASN A 1 689 ? 110.257 145.974 114.403 1.00 87.85  ? 705 ASN A C   1 
ATOM 1880 O O   . ASN A 1 689 ? 111.161 145.491 113.711 1.00 85.71  ? 705 ASN A O   1 
ATOM 1881 C CB  . ASN A 1 689 ? 108.452 144.505 115.336 1.00 86.93  ? 705 ASN A CB  1 
ATOM 1882 C CG  . ASN A 1 689 ? 107.956 143.688 116.511 1.00 84.91  ? 705 ASN A CG  1 
ATOM 1883 O OD1 . ASN A 1 689 ? 108.747 143.161 117.293 1.00 81.15  ? 705 ASN A OD1 1 
ATOM 1884 N ND2 . ASN A 1 689 ? 106.638 143.580 116.644 1.00 85.22  ? 705 ASN A ND2 1 
ATOM 1885 N N   . HIS A 1 690 ? 109.686 147.144 114.111 1.00 87.18  ? 706 HIS A N   1 
ATOM 1886 C CA  . HIS A 1 690 ? 110.076 147.881 112.914 1.00 84.48  ? 706 HIS A CA  1 
ATOM 1887 C C   . HIS A 1 690 ? 111.531 148.329 112.990 1.00 84.53  ? 706 HIS A C   1 
ATOM 1888 O O   . HIS A 1 690 ? 112.281 148.202 112.015 1.00 84.93  ? 706 HIS A O   1 
ATOM 1889 C CB  . HIS A 1 690 ? 109.155 149.085 112.720 1.00 84.25  ? 706 HIS A CB  1 
ATOM 1890 C CG  . HIS A 1 690 ? 109.468 149.894 111.500 1.00 86.33  ? 706 HIS A CG  1 
ATOM 1891 N ND1 . HIS A 1 690 ? 108.964 149.589 110.254 1.00 86.73  ? 706 HIS A ND1 1 
ATOM 1892 C CD2 . HIS A 1 690 ? 110.237 150.997 111.335 1.00 84.20  ? 706 HIS A CD2 1 
ATOM 1893 C CE1 . HIS A 1 690 ? 109.406 150.469 109.374 1.00 86.75  ? 706 HIS A CE1 1 
ATOM 1894 N NE2 . HIS A 1 690 ? 110.181 151.334 110.004 1.00 84.70  ? 706 HIS A NE2 1 
ATOM 1895 N N   . PHE A 1 691 ? 111.951 148.855 114.142 1.00 84.55  ? 707 PHE A N   1 
ATOM 1896 C CA  . PHE A 1 691 ? 113.300 149.392 114.275 1.00 86.50  ? 707 PHE A CA  1 
ATOM 1897 C C   . PHE A 1 691 ? 114.263 148.430 114.955 1.00 89.21  ? 707 PHE A C   1 
ATOM 1898 O O   . PHE A 1 691 ? 115.450 148.413 114.609 1.00 85.88  ? 707 PHE A O   1 
ATOM 1899 C CB  . PHE A 1 691 ? 113.265 150.710 115.053 1.00 85.63  ? 707 PHE A CB  1 
ATOM 1900 C CG  . PHE A 1 691 ? 112.543 151.815 114.336 1.00 86.22  ? 707 PHE A CG  1 
ATOM 1901 C CD1 . PHE A 1 691 ? 113.161 152.510 113.311 1.00 85.43  ? 707 PHE A CD1 1 
ATOM 1902 C CD2 . PHE A 1 691 ? 111.249 152.160 114.687 1.00 88.86  ? 707 PHE A CD2 1 
ATOM 1903 C CE1 . PHE A 1 691 ? 112.503 153.527 112.648 1.00 85.79  ? 707 PHE A CE1 1 
ATOM 1904 C CE2 . PHE A 1 691 ? 110.585 153.178 114.028 1.00 89.84  ? 707 PHE A CE2 1 
ATOM 1905 C CZ  . PHE A 1 691 ? 111.214 153.862 113.007 1.00 88.73  ? 707 PHE A CZ  1 
ATOM 1906 N N   . GLY A 1 692 ? 113.787 147.630 115.905 1.00 84.30  ? 708 GLY A N   1 
ATOM 1907 C CA  . GLY A 1 692 ? 114.670 146.693 116.577 1.00 81.38  ? 708 GLY A CA  1 
ATOM 1908 C C   . GLY A 1 692 ? 115.819 147.397 117.266 1.00 83.62  ? 708 GLY A C   1 
ATOM 1909 O O   . GLY A 1 692 ? 115.643 148.420 117.938 1.00 81.47  ? 708 GLY A O   1 
ATOM 1910 N N   . THR A 1 693 ? 117.019 146.845 117.098 1.00 85.89  ? 709 THR A N   1 
ATOM 1911 C CA  . THR A 1 693 ? 118.222 147.384 117.718 1.00 83.51  ? 709 THR A CA  1 
ATOM 1912 C C   . THR A 1 693 ? 118.922 148.424 116.851 1.00 82.18  ? 709 THR A C   1 
ATOM 1913 O O   . THR A 1 693 ? 119.943 148.977 117.275 1.00 78.31  ? 709 THR A O   1 
ATOM 1914 C CB  . THR A 1 693 ? 119.199 146.250 118.041 1.00 82.67  ? 709 THR A CB  1 
ATOM 1915 O OG1 . THR A 1 693 ? 119.559 145.565 116.834 1.00 82.31  ? 709 THR A OG1 1 
ATOM 1916 C CG2 . THR A 1 693 ? 118.572 145.262 119.015 1.00 82.54  ? 709 THR A CG2 1 
ATOM 1917 N N   . LYS A 1 694 ? 118.404 148.702 115.653 1.00 93.34  ? 710 LYS A N   1 
ATOM 1918 C CA  . LYS A 1 694 ? 119.049 149.674 114.777 1.00 93.10  ? 710 LYS A CA  1 
ATOM 1919 C C   . LYS A 1 694 ? 119.022 151.077 115.369 1.00 91.13  ? 710 LYS A C   1 
ATOM 1920 O O   . LYS A 1 694 ? 119.869 151.909 115.022 1.00 89.25  ? 710 LYS A O   1 
ATOM 1921 C CB  . LYS A 1 694 ? 118.370 149.679 113.408 1.00 94.58  ? 710 LYS A CB  1 
ATOM 1922 C CG  . LYS A 1 694 ? 118.517 148.381 112.632 1.00 95.21  ? 710 LYS A CG  1 
ATOM 1923 C CD  . LYS A 1 694 ? 117.630 148.366 111.392 1.00 94.24  ? 710 LYS A CD  1 
ATOM 1924 C CE  . LYS A 1 694 ? 117.993 149.479 110.417 1.00 93.72  ? 710 LYS A CE  1 
ATOM 1925 N NZ  . LYS A 1 694 ? 117.144 149.448 109.194 1.00 92.25  ? 710 LYS A NZ  1 
ATOM 1926 N N   . VAL A 1 695 ? 118.070 151.359 116.254 1.00 86.92  ? 711 VAL A N   1 
ATOM 1927 C CA  . VAL A 1 695 ? 117.836 152.707 116.752 1.00 85.90  ? 711 VAL A CA  1 
ATOM 1928 C C   . VAL A 1 695 ? 117.934 152.708 118.270 1.00 86.44  ? 711 VAL A C   1 
ATOM 1929 O O   . VAL A 1 695 ? 117.652 151.705 118.935 1.00 88.85  ? 711 VAL A O   1 
ATOM 1930 C CB  . VAL A 1 695 ? 116.461 153.241 116.296 1.00 85.57  ? 711 VAL A CB  1 
ATOM 1931 C CG1 . VAL A 1 695 ? 116.240 154.658 116.799 1.00 86.34  ? 711 VAL A CG1 1 
ATOM 1932 C CG2 . VAL A 1 695 ? 116.345 153.180 114.779 1.00 87.12  ? 711 VAL A CG2 1 
ATOM 1933 N N   . LYS A 1 696 ? 118.338 153.851 118.816 1.00 81.93  ? 712 LYS A N   1 
ATOM 1934 C CA  . LYS A 1 696 ? 118.386 154.074 120.254 1.00 80.06  ? 712 LYS A CA  1 
ATOM 1935 C C   . LYS A 1 696 ? 117.137 154.839 120.670 1.00 79.85  ? 712 LYS A C   1 
ATOM 1936 O O   . LYS A 1 696 ? 116.761 155.820 120.019 1.00 83.82  ? 712 LYS A O   1 
ATOM 1937 C CB  . LYS A 1 696 ? 119.646 154.847 120.645 1.00 77.27  ? 712 LYS A CB  1 
ATOM 1938 C CG  . LYS A 1 696 ? 120.936 154.205 120.155 1.00 77.91  ? 712 LYS A CG  1 
ATOM 1939 C CD  . LYS A 1 696 ? 122.169 154.936 120.671 1.00 82.19  ? 712 LYS A CD  1 
ATOM 1940 C CE  . LYS A 1 696 ? 122.321 156.314 120.045 1.00 85.12  ? 712 LYS A CE  1 
ATOM 1941 N NZ  . LYS A 1 696 ? 122.509 156.248 118.568 1.00 84.40  ? 712 LYS A NZ  1 
ATOM 1942 N N   . TYR A 1 697 ? 116.503 154.394 121.750 1.00 68.89  ? 713 TYR A N   1 
ATOM 1943 C CA  . TYR A 1 697 ? 115.181 154.865 122.135 1.00 65.93  ? 713 TYR A CA  1 
ATOM 1944 C C   . TYR A 1 697 ? 115.253 155.754 123.370 1.00 66.70  ? 713 TYR A C   1 
ATOM 1945 O O   . TYR A 1 697 ? 116.008 155.477 124.307 1.00 71.25  ? 713 TYR A O   1 
ATOM 1946 C CB  . TYR A 1 697 ? 114.245 153.686 122.415 1.00 70.54  ? 713 TYR A CB  1 
ATOM 1947 C CG  . TYR A 1 697 ? 114.117 152.719 121.262 1.00 71.13  ? 713 TYR A CG  1 
ATOM 1948 C CD1 . TYR A 1 697 ? 115.005 151.664 121.115 1.00 74.42  ? 713 TYR A CD1 1 
ATOM 1949 C CD2 . TYR A 1 697 ? 113.107 152.861 120.321 1.00 69.93  ? 713 TYR A CD2 1 
ATOM 1950 C CE1 . TYR A 1 697 ? 114.892 150.777 120.062 1.00 77.47  ? 713 TYR A CE1 1 
ATOM 1951 C CE2 . TYR A 1 697 ? 112.985 151.980 119.265 1.00 73.41  ? 713 TYR A CE2 1 
ATOM 1952 C CZ  . TYR A 1 697 ? 113.880 150.940 119.141 1.00 77.01  ? 713 TYR A CZ  1 
ATOM 1953 O OH  . TYR A 1 697 ? 113.762 150.060 118.091 1.00 80.60  ? 713 TYR A OH  1 
ATOM 1954 N N   . TYR A 1 698 ? 114.459 156.821 123.357 1.00 64.35  ? 714 TYR A N   1 
ATOM 1955 C CA  . TYR A 1 698 ? 114.232 157.671 124.518 1.00 61.03  ? 714 TYR A CA  1 
ATOM 1956 C C   . TYR A 1 698 ? 112.777 157.498 124.934 1.00 60.60  ? 714 TYR A C   1 
ATOM 1957 O O   . TYR A 1 698 ? 111.871 157.679 124.114 1.00 68.64  ? 714 TYR A O   1 
ATOM 1958 C CB  . TYR A 1 698 ? 114.537 159.134 124.195 1.00 61.19  ? 714 TYR A CB  1 
ATOM 1959 C CG  . TYR A 1 698 ? 115.271 159.869 125.295 1.00 63.19  ? 714 TYR A CG  1 
ATOM 1960 C CD1 . TYR A 1 698 ? 114.591 160.383 126.391 1.00 64.30  ? 714 TYR A CD1 1 
ATOM 1961 C CD2 . TYR A 1 698 ? 116.646 160.054 125.232 1.00 67.37  ? 714 TYR A CD2 1 
ATOM 1962 C CE1 . TYR A 1 698 ? 115.261 161.056 127.394 1.00 64.88  ? 714 TYR A CE1 1 
ATOM 1963 C CE2 . TYR A 1 698 ? 117.322 160.726 126.231 1.00 69.63  ? 714 TYR A CE2 1 
ATOM 1964 C CZ  . TYR A 1 698 ? 116.624 161.224 127.309 1.00 66.92  ? 714 TYR A CZ  1 
ATOM 1965 O OH  . TYR A 1 698 ? 117.292 161.894 128.305 1.00 65.38  ? 714 TYR A OH  1 
ATOM 1966 N N   . ILE A 1 699 ? 112.553 157.145 126.198 1.00 57.67  ? 715 ILE A N   1 
ATOM 1967 C CA  . ILE A 1 699 ? 111.232 156.761 126.681 1.00 60.07  ? 715 ILE A CA  1 
ATOM 1968 C C   . ILE A 1 699 ? 110.891 157.599 127.905 1.00 62.13  ? 715 ILE A C   1 
ATOM 1969 O O   . ILE A 1 699 ? 111.744 157.815 128.773 1.00 67.87  ? 715 ILE A O   1 
ATOM 1970 C CB  . ILE A 1 699 ? 111.162 155.259 127.017 1.00 62.37  ? 715 ILE A CB  1 
ATOM 1971 C CG1 . ILE A 1 699 ? 111.641 154.430 125.823 1.00 63.46  ? 715 ILE A CG1 1 
ATOM 1972 C CG2 . ILE A 1 699 ? 109.740 154.868 127.397 1.00 66.10  ? 715 ILE A CG2 1 
ATOM 1973 C CD1 . ILE A 1 699 ? 111.656 152.938 126.072 1.00 67.47  ? 715 ILE A CD1 1 
ATOM 1974 N N   . GLU A 1 700 ? 109.648 158.068 127.968 1.00 65.95  ? 716 GLU A N   1 
ATOM 1975 C CA  . GLU A 1 700 ? 109.146 158.841 129.096 1.00 64.82  ? 716 GLU A CA  1 
ATOM 1976 C C   . GLU A 1 700 ? 108.007 158.081 129.764 1.00 65.97  ? 716 GLU A C   1 
ATOM 1977 O O   . GLU A 1 700 ? 107.179 157.468 129.081 1.00 72.17  ? 716 GLU A O   1 
ATOM 1978 C CB  . GLU A 1 700 ? 108.664 160.219 128.640 1.00 70.55  ? 716 GLU A CB  1 
ATOM 1979 C CG  . GLU A 1 700 ? 108.091 161.077 129.755 1.00 72.68  ? 716 GLU A CG  1 
ATOM 1980 C CD  . GLU A 1 700 ? 107.656 162.446 129.272 1.00 74.24  ? 716 GLU A CD  1 
ATOM 1981 O OE1 . GLU A 1 700 ? 107.875 162.754 128.081 1.00 70.10  ? 716 GLU A OE1 1 
ATOM 1982 O OE2 . GLU A 1 700 ? 107.094 163.213 130.082 1.00 73.22  ? 716 GLU A OE2 1 
ATOM 1983 N N   . THR A 1 701 ? 107.970 158.124 131.092 1.00 67.23  ? 717 THR A N   1 
ATOM 1984 C CA  . THR A 1 701 ? 106.921 157.469 131.858 1.00 76.40  ? 717 THR A CA  1 
ATOM 1985 C C   . THR A 1 701 ? 105.929 158.500 132.389 1.00 77.36  ? 717 THR A C   1 
ATOM 1986 O O   . THR A 1 701 ? 106.174 159.709 132.364 1.00 75.97  ? 717 THR A O   1 
ATOM 1987 C CB  . THR A 1 701 ? 107.511 156.670 133.021 1.00 74.63  ? 717 THR A CB  1 
ATOM 1988 O OG1 . THR A 1 701 ? 108.073 157.566 133.987 1.00 71.16  ? 717 THR A OG1 1 
ATOM 1989 C CG2 . THR A 1 701 ? 108.591 155.716 132.529 1.00 73.88  ? 717 THR A CG2 1 
ATOM 1990 N N   . LYS A 1 702 ? 104.795 158.002 132.875 1.00 84.27  ? 718 LYS A N   1 
ATOM 1991 C CA  . LYS A 1 702 ? 103.759 158.882 133.397 1.00 83.19  ? 718 LYS A CA  1 
ATOM 1992 C C   . LYS A 1 702 ? 104.251 159.622 134.634 1.00 85.07  ? 718 LYS A C   1 
ATOM 1993 O O   . LYS A 1 702 ? 104.934 159.053 135.490 1.00 83.46  ? 718 LYS A O   1 
ATOM 1994 C CB  . LYS A 1 702 ? 102.504 158.078 133.741 1.00 85.00  ? 718 LYS A CB  1 
ATOM 1995 C CG  . LYS A 1 702 ? 101.744 157.554 132.537 1.00 86.98  ? 718 LYS A CG  1 
ATOM 1996 C CD  . LYS A 1 702 ? 100.455 156.876 132.964 1.00 88.25  ? 718 LYS A CD  1 
ATOM 1997 C CE  . LYS A 1 702 ? 99.620  156.464 131.766 1.00 84.78  ? 718 LYS A CE  1 
ATOM 1998 N NZ  . LYS A 1 702 ? 98.328  155.852 132.178 1.00 83.54  ? 718 LYS A NZ  1 
ATOM 1999 N N   . ARG A 1 703 ? 103.900 160.904 134.723 1.00 84.02  ? 719 ARG A N   1 
ATOM 2000 C CA  . ARG A 1 703 ? 104.173 161.690 135.919 1.00 83.23  ? 719 ARG A CA  1 
ATOM 2001 C C   . ARG A 1 703 ? 103.465 161.065 137.117 1.00 82.40  ? 719 ARG A C   1 
ATOM 2002 O O   . ARG A 1 703 ? 104.070 160.938 138.189 1.00 81.53  ? 719 ARG A O   1 
ATOM 2003 C CB  . ARG A 1 703 ? 103.738 163.145 135.728 1.00 81.25  ? 719 ARG A CB  1 
ATOM 2004 C CG  . ARG A 1 703 ? 104.110 164.059 136.886 1.00 79.13  ? 719 ARG A CG  1 
ATOM 2005 C CD  . ARG A 1 703 ? 103.725 165.507 136.611 1.00 81.37  ? 719 ARG A CD  1 
ATOM 2006 N NE  . ARG A 1 703 ? 104.434 166.064 135.464 1.00 82.55  ? 719 ARG A NE  1 
ATOM 2007 C CZ  . ARG A 1 703 ? 103.982 166.057 134.217 1.00 84.57  ? 719 ARG A CZ  1 
ATOM 2008 N NH1 . ARG A 1 703 ? 102.815 165.515 133.905 1.00 82.24  ? 719 ARG A NH1 1 
ATOM 2009 N NH2 . ARG A 1 703 ? 104.720 166.605 133.256 1.00 84.39  ? 719 ARG A NH2 1 
ATOM 2010 N N   . PRO A 1 704 ? 102.187 160.670 136.993 1.00 83.52  ? 720 PRO A N   1 
ATOM 2011 C CA  . PRO A 1 704 ? 101.570 159.889 138.074 1.00 85.07  ? 720 PRO A CA  1 
ATOM 2012 C C   . PRO A 1 704 ? 102.123 158.475 138.125 1.00 87.02  ? 720 PRO A C   1 
ATOM 2013 O O   . PRO A 1 704 ? 101.845 157.658 137.241 1.00 85.77  ? 720 PRO A O   1 
ATOM 2014 C CB  . PRO A 1 704 ? 100.077 159.907 137.720 1.00 84.99  ? 720 PRO A CB  1 
ATOM 2015 C CG  . PRO A 1 704 ? 100.036 160.153 136.260 1.00 83.29  ? 720 PRO A CG  1 
ATOM 2016 C CD  . PRO A 1 704 ? 101.202 161.044 135.961 1.00 82.82  ? 720 PRO A CD  1 
ATOM 2017 N N   . PHE A 1 705 ? 102.908 158.178 139.157 1.00 80.80  ? 721 PHE A N   1 
ATOM 2018 C CA  . PHE A 1 705 ? 103.611 156.903 139.221 1.00 78.29  ? 721 PHE A CA  1 
ATOM 2019 C C   . PHE A 1 705 ? 102.631 155.739 139.305 1.00 77.66  ? 721 PHE A C   1 
ATOM 2020 O O   . PHE A 1 705 ? 101.616 155.808 140.003 1.00 80.94  ? 721 PHE A O   1 
ATOM 2021 C CB  . PHE A 1 705 ? 104.555 156.887 140.423 1.00 76.10  ? 721 PHE A CB  1 
ATOM 2022 C CG  . PHE A 1 705 ? 105.140 155.536 140.714 1.00 78.01  ? 721 PHE A CG  1 
ATOM 2023 C CD1 . PHE A 1 705 ? 105.995 154.930 139.811 1.00 76.23  ? 721 PHE A CD1 1 
ATOM 2024 C CD2 . PHE A 1 705 ? 104.839 154.873 141.892 1.00 78.32  ? 721 PHE A CD2 1 
ATOM 2025 C CE1 . PHE A 1 705 ? 106.536 153.687 140.073 1.00 75.93  ? 721 PHE A CE1 1 
ATOM 2026 C CE2 . PHE A 1 705 ? 105.378 153.630 142.161 1.00 75.77  ? 721 PHE A CE2 1 
ATOM 2027 C CZ  . PHE A 1 705 ? 106.228 153.037 141.250 1.00 73.95  ? 721 PHE A CZ  1 
ATOM 2028 N N   . ASP A 1 706 ? 102.945 154.666 138.580 1.00 79.54  ? 722 ASP A N   1 
ATOM 2029 C CA  . ASP A 1 706 ? 102.151 153.441 138.613 1.00 83.25  ? 722 ASP A CA  1 
ATOM 2030 C C   . ASP A 1 706 ? 103.074 152.281 138.269 1.00 85.95  ? 722 ASP A C   1 
ATOM 2031 O O   . ASP A 1 706 ? 103.617 152.230 137.161 1.00 83.95  ? 722 ASP A O   1 
ATOM 2032 C CB  . ASP A 1 706 ? 100.976 153.514 137.638 1.00 81.38  ? 722 ASP A CB  1 
ATOM 2033 C CG  . ASP A 1 706 ? 100.038 152.328 137.763 1.00 84.10  ? 722 ASP A CG  1 
ATOM 2034 O OD1 . ASP A 1 706 ? 100.283 151.461 138.628 1.00 86.99  ? 722 ASP A OD1 1 
ATOM 2035 O OD2 . ASP A 1 706 ? 99.054  152.264 136.996 1.00 79.95  ? 722 ASP A OD2 1 
ATOM 2036 N N   . ALA A 1 707 ? 103.247 151.354 139.214 1.00 87.57  ? 723 ALA A N   1 
ATOM 2037 C CA  . ALA A 1 707 ? 104.206 150.271 139.032 1.00 84.67  ? 723 ALA A CA  1 
ATOM 2038 C C   . ALA A 1 707 ? 103.869 149.382 137.843 1.00 84.76  ? 723 ALA A C   1 
ATOM 2039 O O   . ALA A 1 707 ? 104.782 148.817 137.230 1.00 87.40  ? 723 ALA A O   1 
ATOM 2040 C CB  . ALA A 1 707 ? 104.282 149.423 140.303 1.00 85.31  ? 723 ALA A CB  1 
ATOM 2041 N N   . ASN A 1 708 ? 102.586 149.237 137.505 1.00 85.03  ? 724 ASN A N   1 
ATOM 2042 C CA  . ASN A 1 708 ? 102.214 148.373 136.389 1.00 87.65  ? 724 ASN A CA  1 
ATOM 2043 C C   . ASN A 1 708 ? 102.796 148.888 135.079 1.00 86.55  ? 724 ASN A C   1 
ATOM 2044 O O   . ASN A 1 708 ? 103.268 148.102 134.247 1.00 89.02  ? 724 ASN A O   1 
ATOM 2045 C CB  . ASN A 1 708 ? 100.693 148.267 136.294 1.00 86.87  ? 724 ASN A CB  1 
ATOM 2046 C CG  . ASN A 1 708 ? 100.075 147.648 137.531 1.00 87.27  ? 724 ASN A CG  1 
ATOM 2047 O OD1 . ASN A 1 708 ? 99.890  146.433 137.606 1.00 85.62  ? 724 ASN A OD1 1 
ATOM 2048 N ND2 . ASN A 1 708 ? 99.752  148.482 138.511 1.00 86.14  ? 724 ASN A ND2 1 
ATOM 2049 N N   . MET A 1 709 ? 102.761 150.206 134.872 1.00 79.22  ? 725 MET A N   1 
ATOM 2050 C CA  . MET A 1 709 ? 103.317 150.781 133.652 1.00 80.47  ? 725 MET A CA  1 
ATOM 2051 C C   . MET A 1 709 ? 104.795 150.445 133.514 1.00 81.24  ? 725 MET A C   1 
ATOM 2052 O O   . MET A 1 709 ? 105.240 149.972 132.459 1.00 80.72  ? 725 MET A O   1 
ATOM 2053 C CB  . MET A 1 709 ? 103.110 152.295 133.660 1.00 83.53  ? 725 MET A CB  1 
ATOM 2054 C CG  . MET A 1 709 ? 103.602 153.009 132.413 1.00 85.81  ? 725 MET A CG  1 
ATOM 2055 S SD  . MET A 1 709 ? 102.684 152.535 130.941 1.00 92.00  ? 725 MET A SD  1 
ATOM 2056 C CE  . MET A 1 709 ? 103.368 153.672 129.742 1.00 87.35  ? 725 MET A CE  1 
ATOM 2057 N N   . ASP A 1 710 ? 105.573 150.683 134.573 1.00 80.37  ? 726 ASP A N   1 
ATOM 2058 C CA  . ASP A 1 710 ? 107.002 150.399 134.522 1.00 78.43  ? 726 ASP A CA  1 
ATOM 2059 C C   . ASP A 1 710 ? 107.260 148.912 134.329 1.00 77.36  ? 726 ASP A C   1 
ATOM 2060 O O   . ASP A 1 710 ? 108.158 148.527 133.573 1.00 77.00  ? 726 ASP A O   1 
ATOM 2061 C CB  . ASP A 1 710 ? 107.679 150.898 135.798 1.00 76.76  ? 726 ASP A CB  1 
ATOM 2062 C CG  . ASP A 1 710 ? 107.490 152.387 136.014 1.00 79.48  ? 726 ASP A CG  1 
ATOM 2063 O OD1 . ASP A 1 710 ? 106.835 153.034 135.170 1.00 79.47  ? 726 ASP A OD1 1 
ATOM 2064 O OD2 . ASP A 1 710 ? 107.997 152.910 137.029 1.00 80.73  ? 726 ASP A OD2 1 
ATOM 2065 N N   . ARG A 1 711 ? 106.490 148.061 135.009 1.00 80.49  ? 727 ARG A N   1 
ATOM 2066 C CA  . ARG A 1 711 ? 106.681 146.621 134.869 1.00 77.86  ? 727 ARG A CA  1 
ATOM 2067 C C   . ARG A 1 711 ? 106.441 146.176 133.432 1.00 78.81  ? 727 ARG A C   1 
ATOM 2068 O O   . ARG A 1 711 ? 107.241 145.422 132.862 1.00 81.84  ? 727 ARG A O   1 
ATOM 2069 C CB  . ARG A 1 711 ? 105.749 145.879 135.828 1.00 76.58  ? 727 ARG A CB  1 
ATOM 2070 C CG  . ARG A 1 711 ? 105.805 144.366 135.709 1.00 79.27  ? 727 ARG A CG  1 
ATOM 2071 C CD  . ARG A 1 711 ? 105.035 143.693 136.833 1.00 81.28  ? 727 ARG A CD  1 
ATOM 2072 N NE  . ARG A 1 711 ? 103.640 144.117 136.875 1.00 82.63  ? 727 ARG A NE  1 
ATOM 2073 C CZ  . ARG A 1 711 ? 102.754 143.696 137.767 1.00 80.36  ? 727 ARG A CZ  1 
ATOM 2074 N NH1 . ARG A 1 711 ? 103.081 142.830 138.713 1.00 81.65  ? 727 ARG A NH1 1 
ATOM 2075 N NH2 . ARG A 1 711 ? 101.507 144.156 137.710 1.00 78.32  ? 727 ARG A NH2 1 
ATOM 2076 N N   . GLU A 1 712 ? 105.344 146.636 132.827 1.00 78.32  ? 728 GLU A N   1 
ATOM 2077 C CA  . GLU A 1 712 ? 105.062 146.272 131.443 1.00 79.22  ? 728 GLU A CA  1 
ATOM 2078 C C   . GLU A 1 712 ? 106.131 146.800 130.498 1.00 78.53  ? 728 GLU A C   1 
ATOM 2079 O O   . GLU A 1 712 ? 106.558 146.084 129.584 1.00 77.96  ? 728 GLU A O   1 
ATOM 2080 C CB  . GLU A 1 712 ? 103.686 146.794 131.032 1.00 81.27  ? 728 GLU A CB  1 
ATOM 2081 C CG  . GLU A 1 712 ? 102.530 146.173 131.801 1.00 85.54  ? 728 GLU A CG  1 
ATOM 2082 C CD  . GLU A 1 712 ? 102.362 144.694 131.514 1.00 85.78  ? 728 GLU A CD  1 
ATOM 2083 O OE1 . GLU A 1 712 ? 103.009 144.191 130.571 1.00 84.91  ? 728 GLU A OE1 1 
ATOM 2084 O OE2 . GLU A 1 712 ? 101.583 144.033 132.232 1.00 84.96  ? 728 GLU A OE2 1 
ATOM 2085 N N   . LEU A 1 713 ? 106.574 148.044 130.698 1.00 71.01  ? 729 LEU A N   1 
ATOM 2086 C CA  . LEU A 1 713 ? 107.608 148.602 129.834 1.00 69.57  ? 729 LEU A CA  1 
ATOM 2087 C C   . LEU A 1 713 ? 108.895 147.793 129.934 1.00 72.70  ? 729 LEU A C   1 
ATOM 2088 O O   . LEU A 1 713 ? 109.527 147.481 128.918 1.00 73.52  ? 729 LEU A O   1 
ATOM 2089 C CB  . LEU A 1 713 ? 107.859 150.064 130.201 1.00 67.60  ? 729 LEU A CB  1 
ATOM 2090 C CG  . LEU A 1 713 ? 108.977 150.769 129.431 1.00 69.41  ? 729 LEU A CG  1 
ATOM 2091 C CD1 . LEU A 1 713 ? 108.714 150.731 127.934 1.00 70.98  ? 729 LEU A CD1 1 
ATOM 2092 C CD2 . LEU A 1 713 ? 109.134 152.202 129.914 1.00 71.70  ? 729 LEU A CD2 1 
ATOM 2093 N N   . LEU A 1 714 ? 109.299 147.442 131.157 1.00 70.00  ? 730 LEU A N   1 
ATOM 2094 C CA  . LEU A 1 714 ? 110.523 146.671 131.338 1.00 65.78  ? 730 LEU A CA  1 
ATOM 2095 C C   . LEU A 1 714 ? 110.399 145.287 130.718 1.00 65.59  ? 730 LEU A C   1 
ATOM 2096 O O   . LEU A 1 714 ? 111.344 144.795 130.090 1.00 66.80  ? 730 LEU A O   1 
ATOM 2097 C CB  . LEU A 1 714 ? 110.861 146.565 132.825 1.00 62.58  ? 730 LEU A CB  1 
ATOM 2098 C CG  . LEU A 1 714 ? 111.254 147.868 133.525 1.00 61.27  ? 730 LEU A CG  1 
ATOM 2099 C CD1 . LEU A 1 714 ? 111.452 147.632 135.013 1.00 60.93  ? 730 LEU A CD1 1 
ATOM 2100 C CD2 . LEU A 1 714 ? 112.510 148.457 132.904 1.00 57.95  ? 730 LEU A CD2 1 
ATOM 2101 N N   . THR A 1 715 ? 109.245 144.637 130.886 1.00 71.29  ? 731 THR A N   1 
ATOM 2102 C CA  . THR A 1 715 ? 109.056 143.325 130.277 1.00 74.78  ? 731 THR A CA  1 
ATOM 2103 C C   . THR A 1 715 ? 109.143 143.407 128.759 1.00 74.50  ? 731 THR A C   1 
ATOM 2104 O O   . THR A 1 715 ? 109.810 142.581 128.122 1.00 77.42  ? 731 THR A O   1 
ATOM 2105 C CB  . THR A 1 715 ? 107.712 142.734 130.701 1.00 78.38  ? 731 THR A CB  1 
ATOM 2106 O OG1 . THR A 1 715 ? 106.667 143.682 130.450 1.00 78.19  ? 731 THR A OG1 1 
ATOM 2107 C CG2 . THR A 1 715 ? 107.728 142.371 132.177 1.00 77.81  ? 731 THR A CG2 1 
ATOM 2108 N N   . GLN A 1 716 ? 108.486 144.404 128.161 1.00 67.23  ? 732 GLN A N   1 
ATOM 2109 C CA  . GLN A 1 716 ? 108.531 144.548 126.710 1.00 68.27  ? 732 GLN A CA  1 
ATOM 2110 C C   . GLN A 1 716 ? 109.952 144.821 126.232 1.00 69.56  ? 732 GLN A C   1 
ATOM 2111 O O   . GLN A 1 716 ? 110.402 144.254 125.230 1.00 70.40  ? 732 GLN A O   1 
ATOM 2112 C CB  . GLN A 1 716 ? 107.587 145.665 126.266 1.00 75.90  ? 732 GLN A CB  1 
ATOM 2113 C CG  . GLN A 1 716 ? 106.113 145.332 126.428 1.00 70.89  ? 732 GLN A CG  1 
ATOM 2114 C CD  . GLN A 1 716 ? 105.671 144.200 125.522 1.00 72.93  ? 732 GLN A CD  1 
ATOM 2115 O OE1 . GLN A 1 716 ? 106.391 143.807 124.605 1.00 78.54  ? 732 GLN A OE1 1 
ATOM 2116 N NE2 . GLN A 1 716 ? 104.483 143.667 125.778 1.00 71.68  ? 732 GLN A NE2 1 
ATOM 2117 N N   . LEU A 1 717 ? 110.676 145.691 126.939 1.00 68.84  ? 733 LEU A N   1 
ATOM 2118 C CA  . LEU A 1 717 ? 112.041 146.009 126.535 1.00 69.46  ? 733 LEU A CA  1 
ATOM 2119 C C   . LEU A 1 717 ? 112.950 144.791 126.645 1.00 68.69  ? 733 LEU A C   1 
ATOM 2120 O O   . LEU A 1 717 ? 113.768 144.539 125.752 1.00 72.80  ? 733 LEU A O   1 
ATOM 2121 C CB  . LEU A 1 717 ? 112.581 147.160 127.382 1.00 68.58  ? 733 LEU A CB  1 
ATOM 2122 C CG  . LEU A 1 717 ? 111.937 148.526 127.136 1.00 64.07  ? 733 LEU A CG  1 
ATOM 2123 C CD1 . LEU A 1 717 ? 112.422 149.537 128.161 1.00 67.26  ? 733 LEU A CD1 1 
ATOM 2124 C CD2 . LEU A 1 717 ? 112.226 149.015 125.725 1.00 68.03  ? 733 LEU A CD2 1 
ATOM 2125 N N   . LYS A 1 718 ? 112.825 144.024 127.729 1.00 67.00  ? 734 LYS A N   1 
ATOM 2126 C CA  . LYS A 1 718 ? 113.673 142.849 127.896 1.00 67.24  ? 734 LYS A CA  1 
ATOM 2127 C C   . LYS A 1 718 ? 113.339 141.779 126.865 1.00 71.32  ? 734 LYS A C   1 
ATOM 2128 O O   . LYS A 1 718 ? 114.230 141.059 126.400 1.00 68.69  ? 734 LYS A O   1 
ATOM 2129 C CB  . LYS A 1 718 ? 113.529 142.291 129.311 1.00 66.90  ? 734 LYS A CB  1 
ATOM 2130 C CG  . LYS A 1 718 ? 114.576 141.246 129.663 1.00 65.27  ? 734 LYS A CG  1 
ATOM 2131 C CD  . LYS A 1 718 ? 114.350 140.652 131.045 1.00 67.89  ? 734 LYS A CD  1 
ATOM 2132 C CE  . LYS A 1 718 ? 113.131 139.746 131.073 1.00 73.69  ? 734 LYS A CE  1 
ATOM 2133 N NZ  . LYS A 1 718 ? 112.995 139.031 132.373 1.00 75.68  ? 734 LYS A NZ  1 
ATOM 2134 N N   . ALA A 1 719 ? 112.060 141.656 126.499 1.00 70.05  ? 735 ALA A N   1 
ATOM 2135 C CA  . ALA A 1 719 ? 111.676 140.657 125.507 1.00 67.48  ? 735 ALA A CA  1 
ATOM 2136 C C   . ALA A 1 719 ? 112.428 140.851 124.197 1.00 69.86  ? 735 ALA A C   1 
ATOM 2137 O O   . ALA A 1 719 ? 112.722 139.873 123.500 1.00 71.86  ? 735 ALA A O   1 
ATOM 2138 C CB  . ALA A 1 719 ? 110.168 140.711 125.265 1.00 69.08  ? 735 ALA A CB  1 
ATOM 2139 N N   . LYS A 1 720 ? 112.749 142.095 123.847 1.00 73.61  ? 736 LYS A N   1 
ATOM 2140 C CA  . LYS A 1 720 ? 113.494 142.398 122.633 1.00 70.60  ? 736 LYS A CA  1 
ATOM 2141 C C   . LYS A 1 720 ? 114.998 142.478 122.864 1.00 71.91  ? 736 LYS A C   1 
ATOM 2142 O O   . LYS A 1 720 ? 115.743 142.715 121.908 1.00 71.91  ? 736 LYS A O   1 
ATOM 2143 C CB  . LYS A 1 720 ? 113.000 143.717 122.031 1.00 70.01  ? 736 LYS A CB  1 
ATOM 2144 C CG  . LYS A 1 720 ? 111.535 143.706 121.621 1.00 75.21  ? 736 LYS A CG  1 
ATOM 2145 C CD  . LYS A 1 720 ? 111.275 142.717 120.494 1.00 73.73  ? 736 LYS A CD  1 
ATOM 2146 C CE  . LYS A 1 720 ? 109.831 142.772 120.026 1.00 73.33  ? 736 LYS A CE  1 
ATOM 2147 N NZ  . LYS A 1 720 ? 108.871 142.442 121.116 1.00 76.08  ? 736 LYS A NZ  1 
ATOM 2148 N N   . GLY A 1 721 ? 115.460 142.288 124.097 1.00 70.15  ? 737 GLY A N   1 
ATOM 2149 C CA  . GLY A 1 721 ? 116.881 142.345 124.372 1.00 67.95  ? 737 GLY A CA  1 
ATOM 2150 C C   . GLY A 1 721 ? 117.457 143.740 124.437 1.00 69.82  ? 737 GLY A C   1 
ATOM 2151 O O   . GLY A 1 721 ? 118.681 143.891 124.477 1.00 69.16  ? 737 GLY A O   1 
ATOM 2152 N N   . LEU A 1 722 ? 116.610 144.771 124.450 1.00 71.61  ? 738 LEU A N   1 
ATOM 2153 C CA  . LEU A 1 722 ? 117.097 146.143 124.522 1.00 68.22  ? 738 LEU A CA  1 
ATOM 2154 C C   . LEU A 1 722 ? 117.637 146.503 125.899 1.00 65.19  ? 738 LEU A C   1 
ATOM 2155 O O   . LEU A 1 722 ? 118.361 147.496 126.024 1.00 65.37  ? 738 LEU A O   1 
ATOM 2156 C CB  . LEU A 1 722 ? 115.980 147.116 124.142 1.00 66.96  ? 738 LEU A CB  1 
ATOM 2157 C CG  . LEU A 1 722 ? 115.524 147.064 122.683 1.00 66.48  ? 738 LEU A CG  1 
ATOM 2158 C CD1 . LEU A 1 722 ? 114.281 147.909 122.481 1.00 70.01  ? 738 LEU A CD1 1 
ATOM 2159 C CD2 . LEU A 1 722 ? 116.635 147.527 121.754 1.00 68.23  ? 738 LEU A CD2 1 
ATOM 2160 N N   . ILE A 1 723 ? 117.300 145.729 126.930 1.00 59.07  ? 739 ILE A N   1 
ATOM 2161 C CA  . ILE A 1 723 ? 117.811 145.934 128.278 1.00 57.45  ? 739 ILE A CA  1 
ATOM 2162 C C   . ILE A 1 723 ? 118.175 144.576 128.865 1.00 60.95  ? 739 ILE A C   1 
ATOM 2163 O O   . ILE A 1 723 ? 117.738 143.528 128.386 1.00 63.14  ? 739 ILE A O   1 
ATOM 2164 C CB  . ILE A 1 723 ? 116.797 146.663 129.186 1.00 55.63  ? 739 ILE A CB  1 
ATOM 2165 C CG1 . ILE A 1 723 ? 115.483 145.882 129.269 1.00 59.75  ? 739 ILE A CG1 1 
ATOM 2166 C CG2 . ILE A 1 723 ? 116.544 148.068 128.667 1.00 58.24  ? 739 ILE A CG2 1 
ATOM 2167 C CD1 . ILE A 1 723 ? 114.460 146.508 130.197 1.00 57.93  ? 739 ILE A CD1 1 
ATOM 2168 N N   . GLY A 1 724 ? 118.992 144.607 129.914 1.00 56.40  ? 740 GLY A N   1 
ATOM 2169 C CA  . GLY A 1 724 ? 119.365 143.389 130.604 1.00 58.34  ? 740 GLY A CA  1 
ATOM 2170 C C   . GLY A 1 724 ? 120.797 142.961 130.330 1.00 62.07  ? 740 GLY A C   1 
ATOM 2171 O O   . GLY A 1 724 ? 121.683 143.763 130.018 1.00 62.38  ? 740 GLY A O   1 
ATOM 2172 N N   . ILE A 1 725 ? 121.014 141.650 130.457 1.00 59.25  ? 741 ILE A N   1 
ATOM 2173 C CA  . ILE A 1 725 ? 122.362 141.095 130.354 1.00 60.16  ? 741 ILE A CA  1 
ATOM 2174 C C   . ILE A 1 725 ? 122.935 141.317 128.961 1.00 61.62  ? 741 ILE A C   1 
ATOM 2175 O O   . ILE A 1 725 ? 124.073 141.776 128.805 1.00 58.92  ? 741 ILE A O   1 
ATOM 2176 C CB  . ILE A 1 725 ? 122.346 139.600 130.726 1.00 57.86  ? 741 ILE A CB  1 
ATOM 2177 C CG1 . ILE A 1 725 ? 121.899 139.421 132.181 1.00 55.64  ? 741 ILE A CG1 1 
ATOM 2178 C CG2 . ILE A 1 725 ? 123.718 138.981 130.500 1.00 59.08  ? 741 ILE A CG2 1 
ATOM 2179 C CD1 . ILE A 1 725 ? 121.590 137.987 132.560 1.00 56.13  ? 741 ILE A CD1 1 
ATOM 2180 N N   . GLY A 1 726 ? 122.160 140.997 127.927 1.00 64.71  ? 742 GLY A N   1 
ATOM 2181 C CA  . GLY A 1 726 ? 122.640 141.057 126.562 1.00 62.76  ? 742 GLY A CA  1 
ATOM 2182 C C   . GLY A 1 726 ? 122.462 142.382 125.861 1.00 66.45  ? 742 GLY A C   1 
ATOM 2183 O O   . GLY A 1 726 ? 122.719 142.470 124.657 1.00 65.96  ? 742 GLY A O   1 
ATOM 2184 N N   . SER A 1 727 ? 122.032 143.418 126.573 1.00 68.34  ? 743 SER A N   1 
ATOM 2185 C CA  . SER A 1 727 ? 121.757 144.701 125.949 1.00 67.94  ? 743 SER A CA  1 
ATOM 2186 C C   . SER A 1 727 ? 122.973 145.619 126.024 1.00 64.14  ? 743 SER A C   1 
ATOM 2187 O O   . SER A 1 727 ? 123.938 145.366 126.751 1.00 59.57  ? 743 SER A O   1 
ATOM 2188 C CB  . SER A 1 727 ? 120.563 145.375 126.621 1.00 68.91  ? 743 SER A CB  1 
ATOM 2189 O OG  . SER A 1 727 ? 120.820 145.605 127.996 1.00 73.33  ? 743 SER A OG  1 
ATOM 2190 N N   . GLU A 1 728 ? 122.913 146.700 125.250 1.00 77.59  ? 744 GLU A N   1 
ATOM 2191 C CA  . GLU A 1 728 ? 123.910 147.761 125.289 1.00 76.02  ? 744 GLU A CA  1 
ATOM 2192 C C   . GLU A 1 728 ? 123.439 148.834 126.263 1.00 75.92  ? 744 GLU A C   1 
ATOM 2193 O O   . GLU A 1 728 ? 122.243 149.139 126.326 1.00 80.68  ? 744 GLU A O   1 
ATOM 2194 C CB  . GLU A 1 728 ? 124.140 148.355 123.899 1.00 75.61  ? 744 GLU A CB  1 
ATOM 2195 C CG  . GLU A 1 728 ? 124.977 147.479 122.974 1.00 78.98  ? 744 GLU A CG  1 
ATOM 2196 C CD  . GLU A 1 728 ? 124.315 146.152 122.656 1.00 80.60  ? 744 GLU A CD  1 
ATOM 2197 O OE1 . GLU A 1 728 ? 123.147 145.958 123.054 1.00 81.50  ? 744 GLU A OE1 1 
ATOM 2198 O OE2 . GLU A 1 728 ? 124.963 145.303 122.010 1.00 73.56  ? 744 GLU A OE2 1 
ATOM 2199 N N   . ARG A 1 729 ? 124.381 149.402 127.018 1.00 61.39  ? 745 ARG A N   1 
ATOM 2200 C CA  . ARG A 1 729 ? 124.023 150.296 128.115 1.00 64.79  ? 745 ARG A CA  1 
ATOM 2201 C C   . ARG A 1 729 ? 123.237 151.509 127.628 1.00 66.48  ? 745 ARG A C   1 
ATOM 2202 O O   . ARG A 1 729 ? 122.176 151.835 128.174 1.00 65.21  ? 745 ARG A O   1 
ATOM 2203 C CB  . ARG A 1 729 ? 125.289 150.737 128.852 1.00 61.73  ? 745 ARG A CB  1 
ATOM 2204 C CG  . ARG A 1 729 ? 125.072 151.878 129.831 1.00 57.69  ? 745 ARG A CG  1 
ATOM 2205 C CD  . ARG A 1 729 ? 126.259 152.046 130.763 1.00 58.88  ? 745 ARG A CD  1 
ATOM 2206 N NE  . ARG A 1 729 ? 126.240 153.336 131.443 1.00 57.87  ? 745 ARG A NE  1 
ATOM 2207 C CZ  . ARG A 1 729 ? 125.466 153.626 132.480 1.00 62.32  ? 745 ARG A CZ  1 
ATOM 2208 N NH1 . ARG A 1 729 ? 124.615 152.743 132.977 1.00 58.48  ? 745 ARG A NH1 1 
ATOM 2209 N NH2 . ARG A 1 729 ? 125.544 154.834 133.030 1.00 64.13  ? 745 ARG A NH2 1 
ATOM 2210 N N   . PHE A 1 730 ? 123.740 152.192 126.602 1.00 63.75  ? 746 PHE A N   1 
ATOM 2211 C CA  . PHE A 1 730 ? 123.180 153.467 126.172 1.00 62.88  ? 746 PHE A CA  1 
ATOM 2212 C C   . PHE A 1 730 ? 122.219 153.343 124.996 1.00 63.97  ? 746 PHE A C   1 
ATOM 2213 O O   . PHE A 1 730 ? 121.804 154.367 124.444 1.00 65.31  ? 746 PHE A O   1 
ATOM 2214 C CB  . PHE A 1 730 ? 124.306 154.440 125.814 1.00 66.32  ? 746 PHE A CB  1 
ATOM 2215 C CG  . PHE A 1 730 ? 124.949 155.080 127.008 1.00 68.40  ? 746 PHE A CG  1 
ATOM 2216 C CD1 . PHE A 1 730 ? 124.382 156.197 127.596 1.00 61.43  ? 746 PHE A CD1 1 
ATOM 2217 C CD2 . PHE A 1 730 ? 126.115 154.565 127.545 1.00 70.59  ? 746 PHE A CD2 1 
ATOM 2218 C CE1 . PHE A 1 730 ? 124.967 156.790 128.696 1.00 63.37  ? 746 PHE A CE1 1 
ATOM 2219 C CE2 . PHE A 1 730 ? 126.706 155.155 128.646 1.00 70.84  ? 746 PHE A CE2 1 
ATOM 2220 C CZ  . PHE A 1 730 ? 126.130 156.269 129.222 1.00 67.55  ? 746 PHE A CZ  1 
ATOM 2221 N N   . GLN A 1 731 ? 121.849 152.124 124.598 1.00 69.67  ? 747 GLN A N   1 
ATOM 2222 C CA  . GLN A 1 731 ? 120.892 151.976 123.508 1.00 67.15  ? 747 GLN A CA  1 
ATOM 2223 C C   . GLN A 1 731 ? 119.486 152.397 123.915 1.00 67.61  ? 747 GLN A C   1 
ATOM 2224 O O   . GLN A 1 731 ? 118.648 152.637 123.039 1.00 73.97  ? 747 GLN A O   1 
ATOM 2225 C CB  . GLN A 1 731 ? 120.881 150.531 123.007 1.00 70.45  ? 747 GLN A CB  1 
ATOM 2226 C CG  . GLN A 1 731 ? 119.893 150.276 121.878 1.00 70.10  ? 747 GLN A CG  1 
ATOM 2227 C CD  . GLN A 1 731 ? 120.221 149.025 121.086 1.00 71.85  ? 747 GLN A CD  1 
ATOM 2228 O OE1 . GLN A 1 731 ? 119.457 148.061 121.080 1.00 70.71  ? 747 GLN A OE1 1 
ATOM 2229 N NE2 . GLN A 1 731 ? 121.361 149.039 120.406 1.00 73.69  ? 747 GLN A NE2 1 
ATOM 2230 N N   . VAL A 1 732 ? 119.206 152.493 125.213 1.00 57.21  ? 748 VAL A N   1 
ATOM 2231 C CA  . VAL A 1 732 ? 117.901 152.906 125.713 1.00 54.86  ? 748 VAL A CA  1 
ATOM 2232 C C   . VAL A 1 732 ? 118.109 153.901 126.846 1.00 57.80  ? 748 VAL A C   1 
ATOM 2233 O O   . VAL A 1 732 ? 118.952 153.682 127.724 1.00 63.27  ? 748 VAL A O   1 
ATOM 2234 C CB  . VAL A 1 732 ? 117.066 151.706 126.197 1.00 60.70  ? 748 VAL A CB  1 
ATOM 2235 C CG1 . VAL A 1 732 ? 115.762 152.183 126.817 1.00 61.28  ? 748 VAL A CG1 1 
ATOM 2236 C CG2 . VAL A 1 732 ? 116.794 150.753 125.047 1.00 60.62  ? 748 VAL A CG2 1 
ATOM 2237 N N   . ILE A 1 733 ? 117.343 154.988 126.825 1.00 53.42  ? 749 ILE A N   1 
ATOM 2238 C CA  . ILE A 1 733 ? 117.361 156.000 127.874 1.00 52.99  ? 749 ILE A CA  1 
ATOM 2239 C C   . ILE A 1 733 ? 115.927 156.252 128.313 1.00 55.93  ? 749 ILE A C   1 
ATOM 2240 O O   . ILE A 1 733 ? 115.021 156.350 127.478 1.00 69.10  ? 749 ILE A O   1 
ATOM 2241 C CB  . ILE A 1 733 ? 118.027 157.309 127.400 1.00 54.33  ? 749 ILE A CB  1 
ATOM 2242 C CG1 . ILE A 1 733 ? 119.447 157.030 126.899 1.00 54.41  ? 749 ILE A CG1 1 
ATOM 2243 C CG2 . ILE A 1 733 ? 118.048 158.330 128.532 1.00 58.41  ? 749 ILE A CG2 1 
ATOM 2244 C CD1 . ILE A 1 733 ? 120.143 158.238 126.309 1.00 57.14  ? 749 ILE A CD1 1 
ATOM 2245 N N   . ILE A 1 734 ? 115.723 156.355 129.624 1.00 46.88  ? 750 ILE A N   1 
ATOM 2246 C CA  . ILE A 1 734 ? 114.400 156.527 130.210 1.00 43.19  ? 750 ILE A CA  1 
ATOM 2247 C C   . ILE A 1 734 ? 114.391 157.823 131.008 1.00 45.40  ? 750 ILE A C   1 
ATOM 2248 O O   . ILE A 1 734 ? 115.298 158.070 131.811 1.00 51.52  ? 750 ILE A O   1 
ATOM 2249 C CB  . ILE A 1 734 ? 114.014 155.332 131.101 1.00 46.38  ? 750 ILE A CB  1 
ATOM 2250 C CG1 . ILE A 1 734 ? 114.037 154.038 130.283 1.00 53.10  ? 750 ILE A CG1 1 
ATOM 2251 C CG2 . ILE A 1 734 ? 112.638 155.553 131.719 1.00 53.36  ? 750 ILE A CG2 1 
ATOM 2252 C CD1 . ILE A 1 734 ? 113.758 152.789 131.091 1.00 57.83  ? 750 ILE A CD1 1 
ATOM 2253 N N   . GLN A 1 735 ? 113.368 158.643 130.784 1.00 63.25  ? 751 GLN A N   1 
ATOM 2254 C CA  . GLN A 1 735 ? 113.176 159.895 131.500 1.00 63.17  ? 751 GLN A CA  1 
ATOM 2255 C C   . GLN A 1 735 ? 111.817 159.882 132.183 1.00 65.78  ? 751 GLN A C   1 
ATOM 2256 O O   . GLN A 1 735 ? 110.928 159.109 131.815 1.00 74.24  ? 751 GLN A O   1 
ATOM 2257 C CB  . GLN A 1 735 ? 113.273 161.098 130.555 1.00 62.78  ? 751 GLN A CB  1 
ATOM 2258 C CG  . GLN A 1 735 ? 112.261 161.075 129.422 1.00 68.31  ? 751 GLN A CG  1 
ATOM 2259 C CD  . GLN A 1 735 ? 112.383 162.275 128.505 1.00 68.06  ? 751 GLN A CD  1 
ATOM 2260 O OE1 . GLN A 1 735 ? 113.172 163.186 128.756 1.00 66.68  ? 751 GLN A OE1 1 
ATOM 2261 N NE2 . GLN A 1 735 ? 111.602 162.280 127.432 1.00 70.66  ? 751 GLN A NE2 1 
ATOM 2262 N N   . SER A 1 736 ? 111.661 160.737 133.191 1.00 55.32  ? 752 SER A N   1 
ATOM 2263 C CA  . SER A 1 736 ? 110.401 160.808 133.916 1.00 63.93  ? 752 SER A CA  1 
ATOM 2264 C C   . SER A 1 736 ? 110.422 162.002 134.857 1.00 68.26  ? 752 SER A C   1 
ATOM 2265 O O   . SER A 1 736 ? 111.449 162.324 135.460 1.00 69.42  ? 752 SER A O   1 
ATOM 2266 C CB  . SER A 1 736 ? 110.139 159.519 134.702 1.00 66.53  ? 752 SER A CB  1 
ATOM 2267 O OG  . SER A 1 736 ? 108.890 159.570 135.366 1.00 67.76  ? 752 SER A OG  1 
ATOM 2268 N N   . PHE A 1 737 ? 109.264 162.655 134.973 1.00 74.49  ? 753 PHE A N   1 
ATOM 2269 C CA  . PHE A 1 737 ? 109.077 163.671 136.000 1.00 72.57  ? 753 PHE A CA  1 
ATOM 2270 C C   . PHE A 1 737 ? 108.937 163.060 137.387 1.00 73.16  ? 753 PHE A C   1 
ATOM 2271 O O   . PHE A 1 737 ? 109.196 163.742 138.384 1.00 67.84  ? 753 PHE A O   1 
ATOM 2272 C CB  . PHE A 1 737 ? 107.841 164.519 135.694 1.00 75.72  ? 753 PHE A CB  1 
ATOM 2273 C CG  . PHE A 1 737 ? 108.020 165.461 134.538 1.00 73.95  ? 753 PHE A CG  1 
ATOM 2274 C CD1 . PHE A 1 737 ? 107.681 165.075 133.254 1.00 70.58  ? 753 PHE A CD1 1 
ATOM 2275 C CD2 . PHE A 1 737 ? 108.519 166.737 134.738 1.00 73.72  ? 753 PHE A CD2 1 
ATOM 2276 C CE1 . PHE A 1 737 ? 107.840 165.941 132.190 1.00 69.97  ? 753 PHE A CE1 1 
ATOM 2277 C CE2 . PHE A 1 737 ? 108.682 167.607 133.678 1.00 71.76  ? 753 PHE A CE2 1 
ATOM 2278 C CZ  . PHE A 1 737 ? 108.342 167.209 132.402 1.00 72.02  ? 753 PHE A CZ  1 
ATOM 2279 N N   . ALA A 1 738 ? 108.533 161.794 137.472 1.00 76.33  ? 754 ALA A N   1 
ATOM 2280 C CA  . ALA A 1 738 ? 108.328 161.118 138.748 1.00 75.20  ? 754 ALA A CA  1 
ATOM 2281 C C   . ALA A 1 738 ? 109.635 160.462 139.175 1.00 76.42  ? 754 ALA A C   1 
ATOM 2282 O O   . ALA A 1 738 ? 110.126 159.544 138.510 1.00 76.87  ? 754 ALA A O   1 
ATOM 2283 C CB  . ALA A 1 738 ? 107.209 160.086 138.636 1.00 73.86  ? 754 ALA A CB  1 
ATOM 2284 N N   . ARG A 1 739 ? 110.197 160.933 140.289 1.00 71.36  ? 755 ARG A N   1 
ATOM 2285 C CA  . ARG A 1 739 ? 111.431 160.346 140.800 1.00 67.37  ? 755 ARG A CA  1 
ATOM 2286 C C   . ARG A 1 739 ? 111.206 158.912 141.261 1.00 70.37  ? 755 ARG A C   1 
ATOM 2287 O O   . ARG A 1 739 ? 112.103 158.067 141.153 1.00 73.99  ? 755 ARG A O   1 
ATOM 2288 C CB  . ARG A 1 739 ? 111.974 161.203 141.943 1.00 65.69  ? 755 ARG A CB  1 
ATOM 2289 C CG  . ARG A 1 739 ? 113.327 160.765 142.469 1.00 70.68  ? 755 ARG A CG  1 
ATOM 2290 C CD  . ARG A 1 739 ? 113.943 161.846 143.341 1.00 72.75  ? 755 ARG A CD  1 
ATOM 2291 N NE  . ARG A 1 739 ? 114.266 163.043 142.573 1.00 72.13  ? 755 ARG A NE  1 
ATOM 2292 C CZ  . ARG A 1 739 ? 114.666 164.190 143.104 1.00 71.55  ? 755 ARG A CZ  1 
ATOM 2293 N NH1 . ARG A 1 739 ? 114.788 164.343 144.412 1.00 70.58  ? 755 ARG A NH1 1 
ATOM 2294 N NH2 . ARG A 1 739 ? 114.948 165.212 142.301 1.00 71.50  ? 755 ARG A NH2 1 
ATOM 2295 N N   . GLU A 1 740 ? 110.010 158.617 141.778 1.00 68.08  ? 756 GLU A N   1 
ATOM 2296 C CA  . GLU A 1 740 ? 109.722 157.267 142.248 1.00 68.65  ? 756 GLU A CA  1 
ATOM 2297 C C   . GLU A 1 740 ? 109.808 156.253 141.115 1.00 69.98  ? 756 GLU A C   1 
ATOM 2298 O O   . GLU A 1 740 ? 110.310 155.141 141.312 1.00 74.98  ? 756 GLU A O   1 
ATOM 2299 C CB  . GLU A 1 740 ? 108.339 157.222 142.897 1.00 74.07  ? 756 GLU A CB  1 
ATOM 2300 C CG  . GLU A 1 740 ? 108.183 158.161 144.083 1.00 78.06  ? 756 GLU A CG  1 
ATOM 2301 C CD  . GLU A 1 740 ? 106.821 158.050 144.738 1.00 78.62  ? 756 GLU A CD  1 
ATOM 2302 O OE1 . GLU A 1 740 ? 106.022 157.192 144.308 1.00 76.69  ? 756 GLU A OE1 1 
ATOM 2303 O OE2 . GLU A 1 740 ? 106.549 158.821 145.681 1.00 75.11  ? 756 GLU A OE2 1 
ATOM 2304 N N   . SER A 1 741 ? 109.316 156.611 139.927 1.00 62.03  ? 757 SER A N   1 
ATOM 2305 C CA  . SER A 1 741 ? 109.420 155.706 138.787 1.00 63.64  ? 757 SER A CA  1 
ATOM 2306 C C   . SER A 1 741 ? 110.876 155.442 138.426 1.00 64.50  ? 757 SER A C   1 
ATOM 2307 O O   . SER A 1 741 ? 111.252 154.303 138.122 1.00 71.38  ? 757 SER A O   1 
ATOM 2308 C CB  . SER A 1 741 ? 108.668 156.286 137.590 1.00 65.85  ? 757 SER A CB  1 
ATOM 2309 O OG  . SER A 1 741 ? 108.787 155.444 136.458 1.00 68.34  ? 757 SER A OG  1 
ATOM 2310 N N   . LEU A 1 742 ? 111.710 156.484 138.450 1.00 58.95  ? 758 LEU A N   1 
ATOM 2311 C CA  . LEU A 1 742 ? 113.127 156.301 138.156 1.00 53.92  ? 758 LEU A CA  1 
ATOM 2312 C C   . LEU A 1 742 ? 113.782 155.388 139.183 1.00 54.71  ? 758 LEU A C   1 
ATOM 2313 O O   . LEU A 1 742 ? 114.590 154.522 138.833 1.00 57.41  ? 758 LEU A O   1 
ATOM 2314 C CB  . LEU A 1 742 ? 113.832 157.657 138.113 1.00 52.41  ? 758 LEU A CB  1 
ATOM 2315 C CG  . LEU A 1 742 ? 113.332 158.642 137.055 1.00 60.05  ? 758 LEU A CG  1 
ATOM 2316 C CD1 . LEU A 1 742 ? 114.115 159.941 137.128 1.00 65.10  ? 758 LEU A CD1 1 
ATOM 2317 C CD2 . LEU A 1 742 ? 113.422 158.041 135.660 1.00 58.34  ? 758 LEU A CD2 1 
ATOM 2318 N N   . ILE A 1 743 ? 113.445 155.569 140.462 1.00 55.10  ? 759 ILE A N   1 
ATOM 2319 C CA  . ILE A 1 743 ? 114.008 154.712 141.503 1.00 52.14  ? 759 ILE A CA  1 
ATOM 2320 C C   . ILE A 1 743 ? 113.567 153.268 141.298 1.00 52.43  ? 759 ILE A C   1 
ATOM 2321 O O   . ILE A 1 743 ? 114.363 152.332 141.443 1.00 61.58  ? 759 ILE A O   1 
ATOM 2322 C CB  . ILE A 1 743 ? 113.609 155.231 142.897 1.00 56.19  ? 759 ILE A CB  1 
ATOM 2323 C CG1 . ILE A 1 743 ? 114.180 156.633 143.137 1.00 55.84  ? 759 ILE A CG1 1 
ATOM 2324 C CG2 . ILE A 1 743 ? 114.081 154.270 143.977 1.00 58.96  ? 759 ILE A CG2 1 
ATOM 2325 C CD1 . ILE A 1 743 ? 115.694 156.706 143.135 1.00 61.30  ? 759 ILE A CD1 1 
ATOM 2326 N N   . ASN A 1 744 ? 112.289 153.063 140.972 1.00 50.93  ? 760 ASN A N   1 
ATOM 2327 C CA  . ASN A 1 744 ? 111.795 151.711 140.735 1.00 55.33  ? 760 ASN A CA  1 
ATOM 2328 C C   . ASN A 1 744 ? 112.511 151.056 139.563 1.00 55.52  ? 760 ASN A C   1 
ATOM 2329 O O   . ASN A 1 744 ? 112.879 149.878 139.640 1.00 61.09  ? 760 ASN A O   1 
ATOM 2330 C CB  . ASN A 1 744 ? 110.287 151.740 140.482 1.00 55.17  ? 760 ASN A CB  1 
ATOM 2331 C CG  . ASN A 1 744 ? 109.730 150.378 140.123 1.00 56.82  ? 760 ASN A CG  1 
ATOM 2332 O OD1 . ASN A 1 744 ? 110.269 149.347 140.525 1.00 58.12  ? 760 ASN A OD1 1 
ATOM 2333 N ND2 . ASN A 1 744 ? 108.645 150.367 139.357 1.00 59.22  ? 760 ASN A ND2 1 
ATOM 2334 N N   . ILE A 1 745 ? 112.716 151.795 138.474 1.00 48.05  ? 761 ILE A N   1 
ATOM 2335 C CA  . ILE A 1 745 ? 113.429 151.239 137.329 1.00 45.21  ? 761 ILE A CA  1 
ATOM 2336 C C   . ILE A 1 745 ? 114.876 150.930 137.694 1.00 47.49  ? 761 ILE A C   1 
ATOM 2337 O O   . ILE A 1 745 ? 115.417 149.889 137.306 1.00 56.76  ? 761 ILE A O   1 
ATOM 2338 C CB  . ILE A 1 745 ? 113.338 152.199 136.130 1.00 52.84  ? 761 ILE A CB  1 
ATOM 2339 C CG1 . ILE A 1 745 ? 111.892 152.276 135.630 1.00 60.63  ? 761 ILE A CG1 1 
ATOM 2340 C CG2 . ILE A 1 745 ? 114.279 151.745 135.019 1.00 48.88  ? 761 ILE A CG2 1 
ATOM 2341 C CD1 . ILE A 1 745 ? 111.663 153.302 134.540 1.00 60.00  ? 761 ILE A CD1 1 
ATOM 2342 N N   . HIS A 1 746 ? 115.526 151.825 138.441 1.00 52.64  ? 762 HIS A N   1 
ATOM 2343 C CA  . HIS A 1 746 ? 116.918 151.607 138.821 1.00 47.55  ? 762 HIS A CA  1 
ATOM 2344 C C   . HIS A 1 746 ? 117.062 150.370 139.696 1.00 50.62  ? 762 HIS A C   1 
ATOM 2345 O O   . HIS A 1 746 ? 118.017 149.599 139.542 1.00 54.14  ? 762 HIS A O   1 
ATOM 2346 C CB  . HIS A 1 746 ? 117.455 152.841 139.546 1.00 44.52  ? 762 HIS A CB  1 
ATOM 2347 C CG  . HIS A 1 746 ? 118.932 152.810 139.782 1.00 45.41  ? 762 HIS A CG  1 
ATOM 2348 N ND1 . HIS A 1 746 ? 119.492 152.314 140.940 1.00 47.59  ? 762 HIS A ND1 1 
ATOM 2349 C CD2 . HIS A 1 746 ? 119.966 153.219 139.010 1.00 47.10  ? 762 HIS A CD2 1 
ATOM 2350 C CE1 . HIS A 1 746 ? 120.807 152.417 140.870 1.00 49.83  ? 762 HIS A CE1 1 
ATOM 2351 N NE2 . HIS A 1 746 ? 121.121 152.963 139.709 1.00 50.54  ? 762 HIS A NE2 1 
ATOM 2352 N N   . ASN A 1 747 ? 116.127 150.165 140.626 1.00 49.62  ? 763 ASN A N   1 
ATOM 2353 C CA  . ASN A 1 747 ? 116.206 149.007 141.509 1.00 52.23  ? 763 ASN A CA  1 
ATOM 2354 C C   . ASN A 1 747 ? 116.153 147.694 140.739 1.00 48.88  ? 763 ASN A C   1 
ATOM 2355 O O   . ASN A 1 747 ? 116.644 146.674 141.234 1.00 50.93  ? 763 ASN A O   1 
ATOM 2356 C CB  . ASN A 1 747 ? 115.077 149.053 142.539 1.00 49.54  ? 763 ASN A CB  1 
ATOM 2357 C CG  . ASN A 1 747 ? 115.202 150.228 143.489 1.00 50.84  ? 763 ASN A CG  1 
ATOM 2358 O OD1 . ASN A 1 747 ? 116.289 150.776 143.677 1.00 50.45  ? 763 ASN A OD1 1 
ATOM 2359 N ND2 . ASN A 1 747 ? 114.089 150.617 144.099 1.00 50.86  ? 763 ASN A ND2 1 
ATOM 2360 N N   . GLN A 1 748 ? 115.574 147.695 139.538 1.00 45.30  ? 764 GLN A N   1 
ATOM 2361 C CA  . GLN A 1 748 ? 115.476 146.490 138.725 1.00 45.47  ? 764 GLN A CA  1 
ATOM 2362 C C   . GLN A 1 748 ? 116.550 146.399 137.653 1.00 40.99  ? 764 GLN A C   1 
ATOM 2363 O O   . GLN A 1 748 ? 117.092 145.313 137.429 1.00 44.45  ? 764 GLN A O   1 
ATOM 2364 C CB  . GLN A 1 748 ? 114.100 146.416 138.052 1.00 48.17  ? 764 GLN A CB  1 
ATOM 2365 C CG  . GLN A 1 748 ? 112.927 146.529 139.013 1.00 48.22  ? 764 GLN A CG  1 
ATOM 2366 C CD  . GLN A 1 748 ? 111.587 146.465 138.307 1.00 52.33  ? 764 GLN A CD  1 
ATOM 2367 O OE1 . GLN A 1 748 ? 111.436 145.778 137.297 1.00 53.69  ? 764 GLN A OE1 1 
ATOM 2368 N NE2 . GLN A 1 748 ? 110.606 147.189 138.834 1.00 52.01  ? 764 GLN A NE2 1 
ATOM 2369 N N   . PHE A 1 749 ? 116.870 147.515 136.984 1.00 37.24  ? 765 PHE A N   1 
ATOM 2370 C CA  . PHE A 1 749 ? 117.883 147.559 135.934 1.00 38.58  ? 765 PHE A CA  1 
ATOM 2371 C C   . PHE A 1 749 ? 118.777 148.776 136.192 1.00 42.84  ? 765 PHE A C   1 
ATOM 2372 O O   . PHE A 1 749 ? 118.508 149.893 135.754 1.00 56.75  ? 765 PHE A O   1 
ATOM 2373 C CB  . PHE A 1 749 ? 117.245 147.617 134.544 1.00 38.99  ? 765 PHE A CB  1 
ATOM 2374 C CG  . PHE A 1 749 ? 116.433 146.402 134.198 1.00 43.47  ? 765 PHE A CG  1 
ATOM 2375 C CD1 . PHE A 1 749 ? 115.129 146.275 134.643 1.00 49.93  ? 765 PHE A CD1 1 
ATOM 2376 C CD2 . PHE A 1 749 ? 116.972 145.390 133.422 1.00 45.60  ? 765 PHE A CD2 1 
ATOM 2377 C CE1 . PHE A 1 749 ? 114.379 145.160 134.325 1.00 54.62  ? 765 PHE A CE1 1 
ATOM 2378 C CE2 . PHE A 1 749 ? 116.226 144.273 133.100 1.00 49.52  ? 765 PHE A CE2 1 
ATOM 2379 C CZ  . PHE A 1 749 ? 114.928 144.158 133.552 1.00 53.42  ? 765 PHE A CZ  1 
ATOM 2380 N N   . SER A 1 750 ? 119.868 148.553 136.927 1.00 41.73  ? 766 SER A N   1 
ATOM 2381 C CA  . SER A 1 750 ? 120.770 149.642 137.280 1.00 48.88  ? 766 SER A CA  1 
ATOM 2382 C C   . SER A 1 750 ? 121.600 150.131 136.101 1.00 49.56  ? 766 SER A C   1 
ATOM 2383 O O   . SER A 1 750 ? 122.076 151.271 136.135 1.00 53.96  ? 766 SER A O   1 
ATOM 2384 C CB  . SER A 1 750 ? 121.697 149.196 138.412 1.00 55.68  ? 766 SER A CB  1 
ATOM 2385 O OG  . SER A 1 750 ? 122.574 150.240 138.797 1.00 66.19  ? 766 SER A OG  1 
ATOM 2386 N N   . ASN A 1 751 ? 121.787 149.311 135.066 1.00 49.60  ? 767 ASN A N   1 
ATOM 2387 C CA  . ASN A 1 751 ? 122.593 149.723 133.924 1.00 55.19  ? 767 ASN A CA  1 
ATOM 2388 C C   . ASN A 1 751 ? 121.861 150.685 132.999 1.00 54.82  ? 767 ASN A C   1 
ATOM 2389 O O   . ASN A 1 751 ? 122.507 151.338 132.173 1.00 61.68  ? 767 ASN A O   1 
ATOM 2390 C CB  . ASN A 1 751 ? 123.046 148.498 133.128 1.00 58.20  ? 767 ASN A CB  1 
ATOM 2391 C CG  . ASN A 1 751 ? 124.285 147.849 133.713 1.00 59.27  ? 767 ASN A CG  1 
ATOM 2392 O OD1 . ASN A 1 751 ? 124.551 147.959 134.910 1.00 56.58  ? 767 ASN A OD1 1 
ATOM 2393 N ND2 . ASN A 1 751 ? 125.055 147.175 132.867 1.00 59.38  ? 767 ASN A ND2 1 
ATOM 2394 N N   . ILE A 1 752 ? 120.544 150.791 133.114 1.00 51.38  ? 768 ILE A N   1 
ATOM 2395 C CA  . ILE A 1 752 ? 119.797 151.699 132.237 1.00 44.14  ? 768 ILE A CA  1 
ATOM 2396 C C   . ILE A 1 752 ? 120.055 153.138 132.671 1.00 50.16  ? 768 ILE A C   1 
ATOM 2397 O O   . ILE A 1 752 ? 119.760 153.493 133.827 1.00 59.11  ? 768 ILE A O   1 
ATOM 2398 C CB  . ILE A 1 752 ? 118.303 151.374 132.282 1.00 45.61  ? 768 ILE A CB  1 
ATOM 2399 C CG1 . ILE A 1 752 ? 118.060 149.938 131.810 1.00 57.13  ? 768 ILE A CG1 1 
ATOM 2400 C CG2 . ILE A 1 752 ? 117.523 152.361 131.421 1.00 48.01  ? 768 ILE A CG2 1 
ATOM 2401 C CD1 . ILE A 1 752 ? 116.617 149.494 131.914 1.00 54.26  ? 768 ILE A CD1 1 
ATOM 2402 N N   . PRO A 1 753 ? 120.594 153.999 131.806 1.00 51.04  ? 769 PRO A N   1 
ATOM 2403 C CA  . PRO A 1 753 ? 120.742 155.412 132.182 1.00 54.04  ? 769 PRO A CA  1 
ATOM 2404 C C   . PRO A 1 753 ? 119.380 156.058 132.393 1.00 53.31  ? 769 PRO A C   1 
ATOM 2405 O O   . PRO A 1 753 ? 118.415 155.749 131.690 1.00 58.85  ? 769 PRO A O   1 
ATOM 2406 C CB  . PRO A 1 753 ? 121.489 156.025 130.992 1.00 57.61  ? 769 PRO A CB  1 
ATOM 2407 C CG  . PRO A 1 753 ? 121.216 155.111 129.857 1.00 56.79  ? 769 PRO A CG  1 
ATOM 2408 C CD  . PRO A 1 753 ? 121.096 153.740 130.446 1.00 52.81  ? 769 PRO A CD  1 
ATOM 2409 N N   . LEU A 1 754 ? 119.308 156.958 133.369 1.00 50.84  ? 770 LEU A N   1 
ATOM 2410 C CA  . LEU A 1 754 ? 118.068 157.625 133.733 1.00 48.15  ? 770 LEU A CA  1 
ATOM 2411 C C   . LEU A 1 754 ? 118.250 159.135 133.683 1.00 55.19  ? 770 LEU A C   1 
ATOM 2412 O O   . LEU A 1 754 ? 119.315 159.662 134.016 1.00 63.20  ? 770 LEU A O   1 
ATOM 2413 C CB  . LEU A 1 754 ? 117.606 157.206 135.133 1.00 47.67  ? 770 LEU A CB  1 
ATOM 2414 C CG  . LEU A 1 754 ? 117.382 155.706 135.332 1.00 47.10  ? 770 LEU A CG  1 
ATOM 2415 C CD1 . LEU A 1 754 ? 116.944 155.414 136.757 1.00 57.14  ? 770 LEU A CD1 1 
ATOM 2416 C CD2 . LEU A 1 754 ? 116.360 155.180 134.339 1.00 51.03  ? 770 LEU A CD2 1 
ATOM 2417 N N   . ALA A 1 755 ? 117.192 159.825 133.263 1.00 55.67  ? 771 ALA A N   1 
ATOM 2418 C CA  . ALA A 1 755 ? 117.175 161.278 133.180 1.00 50.98  ? 771 ALA A CA  1 
ATOM 2419 C C   . ALA A 1 755 ? 115.991 161.800 133.977 1.00 57.20  ? 771 ALA A C   1 
ATOM 2420 O O   . ALA A 1 755 ? 114.916 161.192 133.966 1.00 64.52  ? 771 ALA A O   1 
ATOM 2421 C CB  . ALA A 1 755 ? 117.089 161.751 131.726 1.00 54.79  ? 771 ALA A CB  1 
ATOM 2422 N N   . TYR A 1 756 ? 116.190 162.919 134.668 1.00 61.81  ? 772 TYR A N   1 
ATOM 2423 C CA  . TYR A 1 756 ? 115.158 163.521 135.503 1.00 62.58  ? 772 TYR A CA  1 
ATOM 2424 C C   . TYR A 1 756 ? 114.672 164.806 134.845 1.00 64.47  ? 772 TYR A C   1 
ATOM 2425 O O   . TYR A 1 756 ? 115.471 165.707 134.566 1.00 72.65  ? 772 TYR A O   1 
ATOM 2426 C CB  . TYR A 1 756 ? 115.692 163.800 136.907 1.00 65.00  ? 772 TYR A CB  1 
ATOM 2427 C CG  . TYR A 1 756 ? 114.663 164.383 137.850 1.00 67.49  ? 772 TYR A CG  1 
ATOM 2428 C CD1 . TYR A 1 756 ? 113.626 163.604 138.343 1.00 71.26  ? 772 TYR A CD1 1 
ATOM 2429 C CD2 . TYR A 1 756 ? 114.735 165.709 138.252 1.00 65.50  ? 772 TYR A CD2 1 
ATOM 2430 C CE1 . TYR A 1 756 ? 112.684 164.131 139.205 1.00 71.17  ? 772 TYR A CE1 1 
ATOM 2431 C CE2 . TYR A 1 756 ? 113.798 166.245 139.116 1.00 67.54  ? 772 TYR A CE2 1 
ATOM 2432 C CZ  . TYR A 1 756 ? 112.775 165.452 139.589 1.00 70.89  ? 772 TYR A CZ  1 
ATOM 2433 O OH  . TYR A 1 756 ? 111.840 165.980 140.448 1.00 72.23  ? 772 TYR A OH  1 
ATOM 2434 N N   . LEU A 1 757 ? 113.366 164.886 134.601 1.00 66.77  ? 773 LEU A N   1 
ATOM 2435 C CA  . LEU A 1 757 ? 112.773 166.067 133.992 1.00 70.08  ? 773 LEU A CA  1 
ATOM 2436 C C   . LEU A 1 757 ? 112.328 167.040 135.076 1.00 75.08  ? 773 LEU A C   1 
ATOM 2437 O O   . LEU A 1 757 ? 111.659 166.649 136.037 1.00 77.72  ? 773 LEU A O   1 
ATOM 2438 C CB  . LEU A 1 757 ? 111.587 165.671 133.112 1.00 70.74  ? 773 LEU A CB  1 
ATOM 2439 C CG  . LEU A 1 757 ? 111.943 164.910 131.834 1.00 69.98  ? 773 LEU A CG  1 
ATOM 2440 C CD1 . LEU A 1 757 ? 110.748 164.125 131.317 1.00 69.73  ? 773 LEU A CD1 1 
ATOM 2441 C CD2 . LEU A 1 757 ? 112.443 165.872 130.770 1.00 71.85  ? 773 LEU A CD2 1 
ATOM 2442 N N   . THR A 1 758 ? 112.703 168.308 134.921 1.00 77.60  ? 774 THR A N   1 
ATOM 2443 C CA  . THR A 1 758 ? 112.370 169.325 135.906 1.00 77.93  ? 774 THR A CA  1 
ATOM 2444 C C   . THR A 1 758 ? 112.298 170.683 135.224 1.00 79.87  ? 774 THR A C   1 
ATOM 2445 O O   . THR A 1 758 ? 112.845 170.882 134.137 1.00 79.85  ? 774 THR A O   1 
ATOM 2446 C CB  . THR A 1 758 ? 113.398 169.364 137.045 1.00 77.83  ? 774 THR A CB  1 
ATOM 2447 O OG1 . THR A 1 758 ? 113.021 170.362 138.002 1.00 80.22  ? 774 THR A OG1 1 
ATOM 2448 C CG2 . THR A 1 758 ? 114.788 169.678 136.506 1.00 74.83  ? 774 THR A CG2 1 
ATOM 2449 N N   . SER A 1 759 ? 111.608 171.616 135.880 1.00 85.44  ? 775 SER A N   1 
ATOM 2450 C CA  . SER A 1 759 ? 111.505 172.995 135.423 1.00 85.14  ? 775 SER A CA  1 
ATOM 2451 C C   . SER A 1 759 ? 112.030 173.983 136.457 1.00 83.93  ? 775 SER A C   1 
ATOM 2452 O O   . SER A 1 759 ? 111.752 175.183 136.353 1.00 80.29  ? 775 SER A O   1 
ATOM 2453 C CB  . SER A 1 759 ? 110.054 173.327 135.071 1.00 85.14  ? 775 SER A CB  1 
ATOM 2454 O OG  . SER A 1 759 ? 109.574 172.482 134.040 1.00 85.32  ? 775 SER A OG  1 
ATOM 2455 N N   . THR A 1 760 ? 112.782 173.509 137.448 1.00 93.92  ? 776 THR A N   1 
ATOM 2456 C CA  . THR A 1 760 ? 113.303 174.332 138.536 1.00 93.21  ? 776 THR A CA  1 
ATOM 2457 C C   . THR A 1 760 ? 114.794 174.069 138.715 1.00 90.62  ? 776 THR A C   1 
ATOM 2458 O O   . THR A 1 760 ? 115.281 173.814 139.817 1.00 89.49  ? 776 THR A O   1 
ATOM 2459 C CB  . THR A 1 760 ? 112.548 174.066 139.836 1.00 93.37  ? 776 THR A CB  1 
ATOM 2460 O OG1 . THR A 1 760 ? 112.668 172.682 140.189 1.00 94.11  ? 776 THR A OG1 1 
ATOM 2461 C CG2 . THR A 1 760 ? 111.075 174.424 139.685 1.00 91.05  ? 776 THR A CG2 1 
ATOM 2462 N N   . PHE A 1 761 ? 115.529 174.113 137.603 1.00 86.03  ? 777 PHE A N   1 
ATOM 2463 C CA  . PHE A 1 761 ? 116.957 173.823 137.620 1.00 90.41  ? 777 PHE A CA  1 
ATOM 2464 C C   . PHE A 1 761 ? 117.643 174.567 138.760 1.00 91.35  ? 777 PHE A C   1 
ATOM 2465 O O   . PHE A 1 761 ? 117.636 175.800 138.808 1.00 91.71  ? 777 PHE A O   1 
ATOM 2466 C CB  . PHE A 1 761 ? 117.580 174.220 136.278 1.00 89.51  ? 777 PHE A CB  1 
ATOM 2467 C CG  . PHE A 1 761 ? 118.959 173.653 136.040 1.00 86.93  ? 777 PHE A CG  1 
ATOM 2468 C CD1 . PHE A 1 761 ? 119.542 172.770 136.936 1.00 86.95  ? 777 PHE A CD1 1 
ATOM 2469 C CD2 . PHE A 1 761 ? 119.674 174.015 134.910 1.00 89.23  ? 777 PHE A CD2 1 
ATOM 2470 C CE1 . PHE A 1 761 ? 120.803 172.260 136.706 1.00 89.42  ? 777 PHE A CE1 1 
ATOM 2471 C CE2 . PHE A 1 761 ? 120.937 173.507 134.677 1.00 90.19  ? 777 PHE A CE2 1 
ATOM 2472 C CZ  . PHE A 1 761 ? 121.502 172.628 135.577 1.00 90.56  ? 777 PHE A CZ  1 
ATOM 2473 N N   . SER A 1 762 ? 118.238 173.809 139.677 1.00 95.56  ? 778 SER A N   1 
ATOM 2474 C CA  . SER A 1 762 ? 118.889 174.388 140.842 1.00 95.38  ? 778 SER A CA  1 
ATOM 2475 C C   . SER A 1 762 ? 119.892 173.386 141.392 1.00 96.55  ? 778 SER A C   1 
ATOM 2476 O O   . SER A 1 762 ? 119.879 172.205 141.034 1.00 95.92  ? 778 SER A O   1 
ATOM 2477 C CB  . SER A 1 762 ? 117.870 174.778 141.919 1.00 95.46  ? 778 SER A CB  1 
ATOM 2478 O OG  . SER A 1 762 ? 118.515 175.324 143.057 1.00 96.20  ? 778 SER A OG  1 
ATOM 2479 N N   . GLU A 1 763 ? 120.768 173.879 142.271 1.00 93.63  ? 779 GLU A N   1 
ATOM 2480 C CA  . GLU A 1 763 ? 121.777 173.012 142.869 1.00 91.35  ? 779 GLU A CA  1 
ATOM 2481 C C   . GLU A 1 763 ? 121.143 171.903 143.696 1.00 92.66  ? 779 GLU A C   1 
ATOM 2482 O O   . GLU A 1 763 ? 121.688 170.796 143.770 1.00 91.40  ? 779 GLU A O   1 
ATOM 2483 C CB  . GLU A 1 763 ? 122.733 173.838 143.731 1.00 90.30  ? 779 GLU A CB  1 
ATOM 2484 C CG  . GLU A 1 763 ? 123.862 173.032 144.353 1.00 92.73  ? 779 GLU A CG  1 
ATOM 2485 C CD  . GLU A 1 763 ? 124.851 173.900 145.107 1.00 93.87  ? 779 GLU A CD  1 
ATOM 2486 O OE1 . GLU A 1 763 ? 124.679 175.138 145.107 1.00 94.47  ? 779 GLU A OE1 1 
ATOM 2487 O OE2 . GLU A 1 763 ? 125.801 173.346 145.699 1.00 93.17  ? 779 GLU A OE2 1 
ATOM 2488 N N   . SER A 1 764 ? 120.000 172.176 144.328 1.00 97.07  ? 780 SER A N   1 
ATOM 2489 C CA  . SER A 1 764 ? 119.333 171.149 145.121 1.00 96.43  ? 780 SER A CA  1 
ATOM 2490 C C   . SER A 1 764 ? 118.916 169.972 144.247 1.00 95.13  ? 780 SER A C   1 
ATOM 2491 O O   . SER A 1 764 ? 119.111 168.807 144.616 1.00 94.51  ? 780 SER A O   1 
ATOM 2492 C CB  . SER A 1 764 ? 118.120 171.747 145.835 1.00 94.98  ? 780 SER A CB  1 
ATOM 2493 O OG  . SER A 1 764 ? 118.501 172.819 146.678 1.00 94.82  ? 780 SER A OG  1 
ATOM 2494 N N   . GLU A 1 765 ? 118.340 170.258 143.077 1.00 90.29  ? 781 GLU A N   1 
ATOM 2495 C CA  . GLU A 1 765 ? 117.927 169.187 142.177 1.00 90.11  ? 781 GLU A CA  1 
ATOM 2496 C C   . GLU A 1 765 ? 119.127 168.391 141.681 1.00 88.92  ? 781 GLU A C   1 
ATOM 2497 O O   . GLU A 1 765 ? 119.067 167.160 141.590 1.00 86.00  ? 781 GLU A O   1 
ATOM 2498 C CB  . GLU A 1 765 ? 117.145 169.767 140.998 1.00 88.39  ? 781 GLU A CB  1 
ATOM 2499 C CG  . GLU A 1 765 ? 115.840 170.442 141.390 1.00 88.30  ? 781 GLU A CG  1 
ATOM 2500 C CD  . GLU A 1 765 ? 114.820 169.466 141.942 1.00 90.35  ? 781 GLU A CD  1 
ATOM 2501 O OE1 . GLU A 1 765 ? 115.062 168.243 141.870 1.00 91.71  ? 781 GLU A OE1 1 
ATOM 2502 O OE2 . GLU A 1 765 ? 113.773 169.922 142.449 1.00 89.02  ? 781 GLU A OE2 1 
ATOM 2503 N N   . MET A 1 766 ? 120.222 169.076 141.345 1.00 89.99  ? 782 MET A N   1 
ATOM 2504 C CA  . MET A 1 766 ? 121.418 168.371 140.896 1.00 89.57  ? 782 MET A CA  1 
ATOM 2505 C C   . MET A 1 766 ? 121.976 167.475 141.994 1.00 89.05  ? 782 MET A C   1 
ATOM 2506 O O   . MET A 1 766 ? 122.372 166.334 141.730 1.00 87.10  ? 782 MET A O   1 
ATOM 2507 C CB  . MET A 1 766 ? 122.473 169.375 140.431 1.00 88.78  ? 782 MET A CB  1 
ATOM 2508 C CG  . MET A 1 766 ? 122.208 169.938 139.044 1.00 91.20  ? 782 MET A CG  1 
ATOM 2509 S SD  . MET A 1 766 ? 123.473 171.098 138.491 1.00 98.08  ? 782 MET A SD  1 
ATOM 2510 C CE  . MET A 1 766 ? 122.970 172.589 139.345 1.00 90.36  ? 782 MET A CE  1 
ATOM 2511 N N   . ASP A 1 767 ? 122.017 167.973 143.232 1.00 89.00  ? 783 ASP A N   1 
ATOM 2512 C CA  . ASP A 1 767 ? 122.493 167.151 144.339 1.00 88.15  ? 783 ASP A CA  1 
ATOM 2513 C C   . ASP A 1 767 ? 121.590 165.943 144.551 1.00 89.04  ? 783 ASP A C   1 
ATOM 2514 O O   . ASP A 1 767 ? 122.075 164.827 144.777 1.00 90.78  ? 783 ASP A O   1 
ATOM 2515 C CB  . ASP A 1 767 ? 122.576 167.989 145.615 1.00 89.48  ? 783 ASP A CB  1 
ATOM 2516 C CG  . ASP A 1 767 ? 123.577 169.120 145.503 1.00 91.85  ? 783 ASP A CG  1 
ATOM 2517 O OD1 . ASP A 1 767 ? 124.220 169.243 144.439 1.00 91.58  ? 783 ASP A OD1 1 
ATOM 2518 O OD2 . ASP A 1 767 ? 123.722 169.887 146.478 1.00 91.07  ? 783 ASP A OD2 1 
ATOM 2519 N N   . ASP A 1 768 ? 120.273 166.144 144.483 1.00 82.84  ? 784 ASP A N   1 
ATOM 2520 C CA  . ASP A 1 768 ? 119.346 165.030 144.650 1.00 84.15  ? 784 ASP A CA  1 
ATOM 2521 C C   . ASP A 1 768 ? 119.553 163.982 143.564 1.00 83.28  ? 784 ASP A C   1 
ATOM 2522 O O   . ASP A 1 768 ? 119.598 162.779 143.845 1.00 83.06  ? 784 ASP A O   1 
ATOM 2523 C CB  . ASP A 1 768 ? 117.906 165.543 144.640 1.00 84.84  ? 784 ASP A CB  1 
ATOM 2524 C CG  . ASP A 1 768 ? 117.626 166.513 145.770 1.00 84.42  ? 784 ASP A CG  1 
ATOM 2525 O OD1 . ASP A 1 768 ? 118.548 166.784 146.567 1.00 84.47  ? 784 ASP A OD1 1 
ATOM 2526 O OD2 . ASP A 1 768 ? 116.482 167.007 145.862 1.00 83.74  ? 784 ASP A OD2 1 
ATOM 2527 N N   . CYS A 1 769 ? 119.691 164.423 142.311 1.00 78.62  ? 785 CYS A N   1 
ATOM 2528 C CA  . CYS A 1 769 ? 119.921 163.483 141.219 1.00 78.79  ? 785 CYS A CA  1 
ATOM 2529 C C   . CYS A 1 769 ? 121.241 162.741 141.390 1.00 79.39  ? 785 CYS A C   1 
ATOM 2530 O O   . CYS A 1 769 ? 121.310 161.534 141.130 1.00 78.51  ? 785 CYS A O   1 
ATOM 2531 C CB  . CYS A 1 769 ? 119.892 164.218 139.880 1.00 78.47  ? 785 CYS A CB  1 
ATOM 2532 S SG  . CYS A 1 769 ? 118.254 164.814 139.398 1.00 80.69  ? 785 CYS A SG  1 
ATOM 2533 N N   . LEU A 1 770 ? 122.293 163.439 141.822 1.00 81.69  ? 786 LEU A N   1 
ATOM 2534 C CA  . LEU A 1 770 ? 123.571 162.777 142.061 1.00 80.07  ? 786 LEU A CA  1 
ATOM 2535 C C   . LEU A 1 770 ? 123.452 161.738 143.168 1.00 78.54  ? 786 LEU A C   1 
ATOM 2536 O O   . LEU A 1 770 ? 124.060 160.664 143.087 1.00 77.16  ? 786 LEU A O   1 
ATOM 2537 C CB  . LEU A 1 770 ? 124.637 163.814 142.411 1.00 79.11  ? 786 LEU A CB  1 
ATOM 2538 C CG  . LEU A 1 770 ? 126.032 163.270 142.727 1.00 81.82  ? 786 LEU A CG  1 
ATOM 2539 C CD1 . LEU A 1 770 ? 126.589 162.488 141.547 1.00 78.62  ? 786 LEU A CD1 1 
ATOM 2540 C CD2 . LEU A 1 770 ? 126.970 164.402 143.116 1.00 81.38  ? 786 LEU A CD2 1 
ATOM 2541 N N   . SER A 1 771 ? 122.678 162.042 144.212 1.00 75.92  ? 787 SER A N   1 
ATOM 2542 C CA  . SER A 1 771 ? 122.523 161.098 145.314 1.00 77.76  ? 787 SER A CA  1 
ATOM 2543 C C   . SER A 1 771 ? 121.911 159.787 144.834 1.00 78.20  ? 787 SER A C   1 
ATOM 2544 O O   . SER A 1 771 ? 122.357 158.704 145.232 1.00 76.31  ? 787 SER A O   1 
ATOM 2545 C CB  . SER A 1 771 ? 121.664 161.718 146.415 1.00 78.63  ? 787 SER A CB  1 
ATOM 2546 O OG  . SER A 1 771 ? 121.485 160.814 147.492 1.00 83.74  ? 787 SER A OG  1 
ATOM 2547 N N   . TYR A 1 772 ? 120.892 159.863 143.978 1.00 72.77  ? 788 TYR A N   1 
ATOM 2548 C CA  . TYR A 1 772 ? 120.238 158.665 143.468 1.00 70.12  ? 788 TYR A CA  1 
ATOM 2549 C C   . TYR A 1 772 ? 120.939 158.080 142.248 1.00 70.54  ? 788 TYR A C   1 
ATOM 2550 O O   . TYR A 1 772 ? 120.509 157.033 141.752 1.00 68.91  ? 788 TYR A O   1 
ATOM 2551 C CB  . TYR A 1 772 ? 118.778 158.971 143.126 1.00 72.25  ? 788 TYR A CB  1 
ATOM 2552 C CG  . TYR A 1 772 ? 117.967 159.438 144.314 1.00 75.60  ? 788 TYR A CG  1 
ATOM 2553 C CD1 . TYR A 1 772 ? 117.600 158.553 145.319 1.00 74.68  ? 788 TYR A CD1 1 
ATOM 2554 C CD2 . TYR A 1 772 ? 117.567 160.762 144.431 1.00 75.29  ? 788 TYR A CD2 1 
ATOM 2555 C CE1 . TYR A 1 772 ? 116.860 158.974 146.408 1.00 75.17  ? 788 TYR A CE1 1 
ATOM 2556 C CE2 . TYR A 1 772 ? 116.828 161.192 145.516 1.00 73.52  ? 788 TYR A CE2 1 
ATOM 2557 C CZ  . TYR A 1 772 ? 116.476 160.294 146.500 1.00 76.64  ? 788 TYR A CZ  1 
ATOM 2558 O OH  . TYR A 1 772 ? 115.739 160.719 147.581 1.00 76.34  ? 788 TYR A OH  1 
ATOM 2559 N N   . GLY A 1 773 ? 121.995 158.721 141.756 1.00 63.98  ? 789 GLY A N   1 
ATOM 2560 C CA  . GLY A 1 773 ? 122.772 158.159 140.669 1.00 59.57  ? 789 GLY A CA  1 
ATOM 2561 C C   . GLY A 1 773 ? 122.142 158.277 139.300 1.00 62.12  ? 789 GLY A C   1 
ATOM 2562 O O   . GLY A 1 773 ? 122.378 157.419 138.444 1.00 58.70  ? 789 GLY A O   1 
ATOM 2563 N N   . PHE A 1 774 ? 121.345 159.316 139.064 1.00 69.38  ? 790 PHE A N   1 
ATOM 2564 C CA  . PHE A 1 774 ? 120.780 159.527 137.742 1.00 64.96  ? 790 PHE A CA  1 
ATOM 2565 C C   . PHE A 1 774 ? 121.870 159.952 136.761 1.00 55.78  ? 790 PHE A C   1 
ATOM 2566 O O   . PHE A 1 774 ? 122.836 160.633 137.116 1.00 58.41  ? 790 PHE A O   1 
ATOM 2567 C CB  . PHE A 1 774 ? 119.673 160.582 137.789 1.00 61.51  ? 790 PHE A CB  1 
ATOM 2568 C CG  . PHE A 1 774 ? 118.515 160.215 138.679 1.00 59.34  ? 790 PHE A CG  1 
ATOM 2569 C CD1 . PHE A 1 774 ? 118.269 158.895 139.020 1.00 62.32  ? 790 PHE A CD1 1 
ATOM 2570 C CD2 . PHE A 1 774 ? 117.670 161.195 139.173 1.00 61.64  ? 790 PHE A CD2 1 
ATOM 2571 C CE1 . PHE A 1 774 ? 117.206 158.561 139.836 1.00 67.28  ? 790 PHE A CE1 1 
ATOM 2572 C CE2 . PHE A 1 774 ? 116.604 160.865 139.990 1.00 60.84  ? 790 PHE A CE2 1 
ATOM 2573 C CZ  . PHE A 1 774 ? 116.373 159.547 140.321 1.00 61.95  ? 790 PHE A CZ  1 
ATOM 2574 N N   . TYR A 1 775 ? 121.702 159.535 135.505 1.00 53.46  ? 791 TYR A N   1 
ATOM 2575 C CA  . TYR A 1 775 ? 122.712 159.812 134.489 1.00 55.65  ? 791 TYR A CA  1 
ATOM 2576 C C   . TYR A 1 775 ? 122.699 161.273 134.056 1.00 62.17  ? 791 TYR A C   1 
ATOM 2577 O O   . TYR A 1 775 ? 123.760 161.854 133.801 1.00 68.62  ? 791 TYR A O   1 
ATOM 2578 C CB  . TYR A 1 775 ? 122.500 158.904 133.278 1.00 59.79  ? 791 TYR A CB  1 
ATOM 2579 C CG  . TYR A 1 775 ? 123.315 159.308 132.070 1.00 61.25  ? 791 TYR A CG  1 
ATOM 2580 C CD1 . TYR A 1 775 ? 124.662 158.984 131.977 1.00 65.25  ? 791 TYR A CD1 1 
ATOM 2581 C CD2 . TYR A 1 775 ? 122.738 160.013 131.022 1.00 61.53  ? 791 TYR A CD2 1 
ATOM 2582 C CE1 . TYR A 1 775 ? 125.411 159.353 130.877 1.00 65.12  ? 791 TYR A CE1 1 
ATOM 2583 C CE2 . TYR A 1 775 ? 123.479 160.385 129.918 1.00 65.94  ? 791 TYR A CE2 1 
ATOM 2584 C CZ  . TYR A 1 775 ? 124.814 160.052 129.850 1.00 68.82  ? 791 TYR A CZ  1 
ATOM 2585 O OH  . TYR A 1 775 ? 125.556 160.420 128.753 1.00 73.39  ? 791 TYR A OH  1 
ATOM 2586 N N   . ALA A 1 776 ? 121.519 161.883 133.967 1.00 66.65  ? 792 ALA A N   1 
ATOM 2587 C CA  . ALA A 1 776 ? 121.393 163.230 133.433 1.00 61.48  ? 792 ALA A CA  1 
ATOM 2588 C C   . ALA A 1 776 ? 120.201 163.929 134.069 1.00 65.91  ? 792 ALA A C   1 
ATOM 2589 O O   . ALA A 1 776 ? 119.324 163.298 134.663 1.00 70.23  ? 792 ALA A O   1 
ATOM 2590 C CB  . ALA A 1 776 ? 121.232 163.217 131.907 1.00 61.94  ? 792 ALA A CB  1 
ATOM 2591 N N   . ILE A 1 777 ? 120.190 165.253 133.939 1.00 75.85  ? 793 ILE A N   1 
ATOM 2592 C CA  . ILE A 1 777 ? 119.093 166.099 134.393 1.00 74.64  ? 793 ILE A CA  1 
ATOM 2593 C C   . ILE A 1 777 ? 118.609 166.911 133.201 1.00 76.96  ? 793 ILE A C   1 
ATOM 2594 O O   . ILE A 1 777 ? 119.421 167.474 132.457 1.00 77.11  ? 793 ILE A O   1 
ATOM 2595 C CB  . ILE A 1 777 ? 119.528 167.015 135.550 1.00 74.08  ? 793 ILE A CB  1 
ATOM 2596 C CG1 . ILE A 1 777 ? 118.331 167.807 136.081 1.00 76.70  ? 793 ILE A CG1 1 
ATOM 2597 C CG2 . ILE A 1 777 ? 120.631 167.960 135.096 1.00 77.62  ? 793 ILE A CG2 1 
ATOM 2598 C CD1 . ILE A 1 777 ? 118.646 168.631 137.312 1.00 79.38  ? 793 ILE A CD1 1 
ATOM 2599 N N   . ALA A 1 778 ? 117.289 166.968 133.016 1.00 74.01  ? 794 ALA A N   1 
ATOM 2600 C CA  . ALA A 1 778 ? 116.677 167.616 131.859 1.00 71.94  ? 794 ALA A CA  1 
ATOM 2601 C C   . ALA A 1 778 ? 115.911 168.855 132.310 1.00 76.08  ? 794 ALA A C   1 
ATOM 2602 O O   . ALA A 1 778 ? 114.682 168.813 132.465 1.00 73.73  ? 794 ALA A O   1 
ATOM 2603 C CB  . ALA A 1 778 ? 115.758 166.647 131.119 1.00 68.72  ? 794 ALA A CB  1 
ATOM 2604 N N   . PRO A 1 779 ? 116.600 169.971 132.532 1.00 83.95  ? 795 PRO A N   1 
ATOM 2605 C CA  . PRO A 1 779 ? 115.907 171.208 132.902 1.00 85.98  ? 795 PRO A CA  1 
ATOM 2606 C C   . PRO A 1 779 ? 115.351 171.941 131.691 1.00 85.67  ? 795 PRO A C   1 
ATOM 2607 O O   . PRO A 1 779 ? 115.795 171.751 130.556 1.00 82.70  ? 795 PRO A O   1 
ATOM 2608 C CB  . PRO A 1 779 ? 117.007 172.030 133.581 1.00 85.05  ? 795 PRO A CB  1 
ATOM 2609 C CG  . PRO A 1 779 ? 118.254 171.589 132.899 1.00 81.81  ? 795 PRO A CG  1 
ATOM 2610 C CD  . PRO A 1 779 ? 118.064 170.125 132.590 1.00 82.50  ? 795 PRO A CD  1 
ATOM 2611 N N   . LYS A 1 780 ? 114.363 172.794 131.954 1.00 86.82  ? 796 LYS A N   1 
ATOM 2612 C CA  . LYS A 1 780 ? 113.809 173.639 130.904 1.00 86.70  ? 796 LYS A CA  1 
ATOM 2613 C C   . LYS A 1 780 ? 114.888 174.569 130.365 1.00 89.49  ? 796 LYS A C   1 
ATOM 2614 O O   . LYS A 1 780 ? 115.697 175.108 131.125 1.00 90.00  ? 796 LYS A O   1 
ATOM 2615 C CB  . LYS A 1 780 ? 112.625 174.444 131.445 1.00 87.23  ? 796 LYS A CB  1 
ATOM 2616 C CG  . LYS A 1 780 ? 112.001 175.414 130.442 1.00 88.02  ? 796 LYS A CG  1 
ATOM 2617 C CD  . LYS A 1 780 ? 111.375 174.702 129.247 1.00 86.40  ? 796 LYS A CD  1 
ATOM 2618 C CE  . LYS A 1 780 ? 110.062 174.028 129.611 1.00 88.74  ? 796 LYS A CE  1 
ATOM 2619 N NZ  . LYS A 1 780 ? 108.992 175.016 129.919 1.00 89.93  ? 796 LYS A NZ  1 
ATOM 2620 N N   . TYR A 1 781 ? 114.892 174.762 129.043 1.00 90.55  ? 797 TYR A N   1 
ATOM 2621 C CA  . TYR A 1 781 ? 115.969 175.519 128.412 1.00 90.48  ? 797 TYR A CA  1 
ATOM 2622 C C   . TYR A 1 781 ? 116.022 176.951 128.929 1.00 89.41  ? 797 TYR A C   1 
ATOM 2623 O O   . TYR A 1 781 ? 117.104 177.540 129.038 1.00 89.19  ? 797 TYR A O   1 
ATOM 2624 C CB  . TYR A 1 781 ? 115.800 175.502 126.893 1.00 89.42  ? 797 TYR A CB  1 
ATOM 2625 C CG  . TYR A 1 781 ? 114.662 176.360 126.387 1.00 90.18  ? 797 TYR A CG  1 
ATOM 2626 C CD1 . TYR A 1 781 ? 113.360 175.879 126.362 1.00 92.81  ? 797 TYR A CD1 1 
ATOM 2627 C CD2 . TYR A 1 781 ? 114.892 177.651 125.929 1.00 88.62  ? 797 TYR A CD2 1 
ATOM 2628 C CE1 . TYR A 1 781 ? 112.318 176.661 125.898 1.00 93.98  ? 797 TYR A CE1 1 
ATOM 2629 C CE2 . TYR A 1 781 ? 113.857 178.439 125.463 1.00 90.79  ? 797 TYR A CE2 1 
ATOM 2630 C CZ  . TYR A 1 781 ? 112.573 177.939 125.450 1.00 93.96  ? 797 TYR A CZ  1 
ATOM 2631 O OH  . TYR A 1 781 ? 111.541 178.721 124.988 1.00 93.75  ? 797 TYR A OH  1 
ATOM 2632 N N   . THR A 1 782 ? 114.865 177.531 129.253 1.00 90.73  ? 798 THR A N   1 
ATOM 2633 C CA  . THR A 1 782 ? 114.831 178.911 129.724 1.00 91.81  ? 798 THR A CA  1 
ATOM 2634 C C   . THR A 1 782 ? 115.565 179.093 131.046 1.00 90.75  ? 798 THR A C   1 
ATOM 2635 O O   . THR A 1 782 ? 116.007 180.206 131.348 1.00 89.61  ? 798 THR A O   1 
ATOM 2636 C CB  . THR A 1 782 ? 113.382 179.380 129.877 1.00 90.45  ? 798 THR A CB  1 
ATOM 2637 O OG1 . THR A 1 782 ? 112.707 178.554 130.835 1.00 89.63  ? 798 THR A OG1 1 
ATOM 2638 C CG2 . THR A 1 782 ? 112.650 179.308 128.545 1.00 87.45  ? 798 THR A CG2 1 
ATOM 2639 N N   . THR A 1 783 ? 115.705 178.030 131.837 1.00 88.48  ? 799 THR A N   1 
ATOM 2640 C CA  . THR A 1 783 ? 116.334 178.114 133.149 1.00 88.87  ? 799 THR A CA  1 
ATOM 2641 C C   . THR A 1 783 ? 117.809 177.735 133.135 1.00 89.14  ? 799 THR A C   1 
ATOM 2642 O O   . THR A 1 783 ? 118.425 177.680 134.205 1.00 89.78  ? 799 THR A O   1 
ATOM 2643 C CB  . THR A 1 783 ? 115.600 177.208 134.144 1.00 86.19  ? 799 THR A CB  1 
ATOM 2644 O OG1 . THR A 1 783 ? 115.734 175.840 133.737 1.00 89.58  ? 799 THR A OG1 1 
ATOM 2645 C CG2 . THR A 1 783 ? 114.124 177.569 134.209 1.00 85.95  ? 799 THR A CG2 1 
ATOM 2646 N N   . ILE A 1 784 ? 118.386 177.473 131.967 1.00 89.99  ? 800 ILE A N   1 
ATOM 2647 C CA  . ILE A 1 784 ? 119.762 176.998 131.884 1.00 90.44  ? 800 ILE A CA  1 
ATOM 2648 C C   . ILE A 1 784 ? 120.707 178.183 131.751 1.00 92.54  ? 800 ILE A C   1 
ATOM 2649 O O   . ILE A 1 784 ? 120.430 179.148 131.028 1.00 92.01  ? 800 ILE A O   1 
ATOM 2650 C CB  . ILE A 1 784 ? 119.925 176.021 130.706 1.00 89.80  ? 800 ILE A CB  1 
ATOM 2651 C CG1 . ILE A 1 784 ? 118.956 174.847 130.861 1.00 90.70  ? 800 ILE A CG1 1 
ATOM 2652 C CG2 . ILE A 1 784 ? 121.364 175.520 130.622 1.00 90.71  ? 800 ILE A CG2 1 
ATOM 2653 C CD1 . ILE A 1 784 ? 119.008 173.846 129.728 1.00 91.78  ? 800 ILE A CD1 1 
ATOM 2654 N N   . THR A 1 785 ? 121.833 178.108 132.457 1.00 96.60  ? 801 THR A N   1 
ATOM 2655 C CA  . THR A 1 785 ? 122.897 179.095 132.361 1.00 94.87  ? 801 THR A CA  1 
ATOM 2656 C C   . THR A 1 785 ? 124.233 178.370 132.403 1.00 93.25  ? 801 THR A C   1 
ATOM 2657 O O   . THR A 1 785 ? 124.336 177.259 132.931 1.00 96.64  ? 801 THR A O   1 
ATOM 2658 C CB  . THR A 1 785 ? 122.827 180.130 133.491 1.00 97.53  ? 801 THR A CB  1 
ATOM 2659 O OG1 . THR A 1 785 ? 122.925 179.468 134.758 1.00 96.14  ? 801 THR A OG1 1 
ATOM 2660 C CG2 . THR A 1 785 ? 121.521 180.908 133.426 1.00 96.47  ? 801 THR A CG2 1 
ATOM 2661 N N   . LYS A 1 786 ? 125.262 179.008 131.840 1.00 92.23  ? 802 LYS A N   1 
ATOM 2662 C CA  . LYS A 1 786 ? 126.573 178.369 131.784 1.00 94.11  ? 802 LYS A CA  1 
ATOM 2663 C C   . LYS A 1 786 ? 127.086 178.018 133.173 1.00 93.61  ? 802 LYS A C   1 
ATOM 2664 O O   . LYS A 1 786 ? 127.769 177.002 133.342 1.00 92.00  ? 802 LYS A O   1 
ATOM 2665 C CB  . LYS A 1 786 ? 127.574 179.272 131.065 1.00 93.69  ? 802 LYS A CB  1 
ATOM 2666 C CG  . LYS A 1 786 ? 129.008 178.770 131.138 1.00 93.72  ? 802 LYS A CG  1 
ATOM 2667 C CD  . LYS A 1 786 ? 129.910 179.487 130.149 1.00 94.02  ? 802 LYS A CD  1 
ATOM 2668 C CE  . LYS A 1 786 ? 131.365 179.089 130.339 1.00 93.15  ? 802 LYS A CE  1 
ATOM 2669 N NZ  . LYS A 1 786 ? 131.561 177.613 130.271 1.00 93.48  ? 802 LYS A NZ  1 
ATOM 2670 N N   . GLU A 1 787 ? 126.774 178.840 134.177 1.00 95.63  ? 803 GLU A N   1 
ATOM 2671 C CA  . GLU A 1 787 ? 127.192 178.530 135.540 1.00 97.60  ? 803 GLU A CA  1 
ATOM 2672 C C   . GLU A 1 787 ? 126.603 177.202 135.998 1.00 96.87  ? 803 GLU A C   1 
ATOM 2673 O O   . GLU A 1 787 ? 127.312 176.346 136.542 1.00 92.84  ? 803 GLU A O   1 
ATOM 2674 C CB  . GLU A 1 787 ? 126.775 179.661 136.482 1.00 96.89  ? 803 GLU A CB  1 
ATOM 2675 C CG  . GLU A 1 787 ? 127.156 179.443 137.942 1.00 95.67  ? 803 GLU A CG  1 
ATOM 2676 C CD  . GLU A 1 787 ? 128.656 179.376 138.154 1.00 95.88  ? 803 GLU A CD  1 
ATOM 2677 O OE1 . GLU A 1 787 ? 129.408 179.725 137.220 1.00 95.44  ? 803 GLU A OE1 1 
ATOM 2678 O OE2 . GLU A 1 787 ? 129.084 178.974 139.256 1.00 95.43  ? 803 GLU A OE2 1 
ATOM 2679 N N   . LEU A 1 788 ? 125.302 177.007 135.776 1.00 97.88  ? 804 LEU A N   1 
ATOM 2680 C CA  . LEU A 1 788 ? 124.658 175.762 136.175 1.00 97.23  ? 804 LEU A CA  1 
ATOM 2681 C C   . LEU A 1 788 ? 125.160 174.575 135.364 1.00 93.35  ? 804 LEU A C   1 
ATOM 2682 O O   . LEU A 1 788 ? 125.304 173.478 135.910 1.00 90.99  ? 804 LEU A O   1 
ATOM 2683 C CB  . LEU A 1 788 ? 123.140 175.890 136.040 1.00 97.28  ? 804 LEU A CB  1 
ATOM 2684 C CG  . LEU A 1 788 ? 122.489 176.984 136.892 1.00 96.55  ? 804 LEU A CG  1 
ATOM 2685 C CD1 . LEU A 1 788 ? 120.984 177.011 136.670 1.00 93.54  ? 804 LEU A CD1 1 
ATOM 2686 C CD2 . LEU A 1 788 ? 122.808 176.795 138.368 1.00 94.44  ? 804 LEU A CD2 1 
ATOM 2687 N N   . VAL A 1 789 ? 125.428 174.767 134.071 1.00 91.94  ? 805 VAL A N   1 
ATOM 2688 C CA  . VAL A 1 789 ? 125.972 173.681 133.261 1.00 90.04  ? 805 VAL A CA  1 
ATOM 2689 C C   . VAL A 1 789 ? 127.343 173.265 133.780 1.00 89.86  ? 805 VAL A C   1 
ATOM 2690 O O   . VAL A 1 789 ? 127.643 172.070 133.894 1.00 91.33  ? 805 VAL A O   1 
ATOM 2691 C CB  . VAL A 1 789 ? 126.029 174.100 131.781 1.00 90.77  ? 805 VAL A CB  1 
ATOM 2692 C CG1 . VAL A 1 789 ? 126.703 173.020 130.944 1.00 91.09  ? 805 VAL A CG1 1 
ATOM 2693 C CG2 . VAL A 1 789 ? 124.632 174.384 131.258 1.00 90.92  ? 805 VAL A CG2 1 
ATOM 2694 N N   . ASP A 1 790 ? 128.198 174.241 134.093 1.00 95.04  ? 806 ASP A N   1 
ATOM 2695 C CA  . ASP A 1 790 ? 129.510 173.922 134.646 1.00 95.12  ? 806 ASP A CA  1 
ATOM 2696 C C   . ASP A 1 790 ? 129.381 173.223 135.993 1.00 92.14  ? 806 ASP A C   1 
ATOM 2697 O O   . ASP A 1 790 ? 130.119 172.275 136.283 1.00 89.25  ? 806 ASP A O   1 
ATOM 2698 C CB  . ASP A 1 790 ? 130.344 175.196 134.780 1.00 96.15  ? 806 ASP A CB  1 
ATOM 2699 C CG  . ASP A 1 790 ? 130.589 175.875 133.447 1.00 96.63  ? 806 ASP A CG  1 
ATOM 2700 O OD1 . ASP A 1 790 ? 130.661 175.165 132.422 1.00 96.08  ? 806 ASP A OD1 1 
ATOM 2701 O OD2 . ASP A 1 790 ? 130.708 177.118 133.423 1.00 95.10  ? 806 ASP A OD2 1 
ATOM 2702 N N   . LEU A 1 791 ? 128.449 173.681 136.832 1.00 89.96  ? 807 LEU A N   1 
ATOM 2703 C CA  . LEU A 1 791 ? 128.233 173.027 138.118 1.00 90.63  ? 807 LEU A CA  1 
ATOM 2704 C C   . LEU A 1 791 ? 127.795 171.579 137.931 1.00 92.66  ? 807 LEU A C   1 
ATOM 2705 O O   . LEU A 1 791 ? 128.272 170.682 138.637 1.00 92.03  ? 807 LEU A O   1 
ATOM 2706 C CB  . LEU A 1 791 ? 127.195 173.804 138.927 1.00 89.62  ? 807 LEU A CB  1 
ATOM 2707 C CG  . LEU A 1 791 ? 126.862 173.264 140.319 1.00 89.43  ? 807 LEU A CG  1 
ATOM 2708 C CD1 . LEU A 1 791 ? 128.101 173.233 141.198 1.00 89.50  ? 807 LEU A CD1 1 
ATOM 2709 C CD2 . LEU A 1 791 ? 125.768 174.101 140.962 1.00 89.74  ? 807 LEU A CD2 1 
ATOM 2710 N N   . ALA A 1 792 ? 126.887 171.332 136.985 1.00 88.51  ? 808 ALA A N   1 
ATOM 2711 C CA  . ALA A 1 792 ? 126.443 169.969 136.716 1.00 80.32  ? 808 ALA A CA  1 
ATOM 2712 C C   . ALA A 1 792 ? 127.597 169.108 136.220 1.00 82.08  ? 808 ALA A C   1 
ATOM 2713 O O   . ALA A 1 792 ? 127.753 167.956 136.642 1.00 85.30  ? 808 ALA A O   1 
ATOM 2714 C CB  . ALA A 1 792 ? 125.308 169.980 135.693 1.00 82.21  ? 808 ALA A CB  1 
ATOM 2715 N N   . HIS A 1 793 ? 128.417 169.652 135.319 1.00 85.25  ? 809 HIS A N   1 
ATOM 2716 C CA  . HIS A 1 793 ? 129.561 168.898 134.819 1.00 84.90  ? 809 HIS A CA  1 
ATOM 2717 C C   . HIS A 1 793 ? 130.546 168.577 135.935 1.00 83.25  ? 809 HIS A C   1 
ATOM 2718 O O   . HIS A 1 793 ? 131.125 167.484 135.953 1.00 78.18  ? 809 HIS A O   1 
ATOM 2719 C CB  . HIS A 1 793 ? 130.256 169.672 133.700 1.00 86.85  ? 809 HIS A CB  1 
ATOM 2720 C CG  . HIS A 1 793 ? 129.523 169.632 132.395 1.00 85.08  ? 809 HIS A CG  1 
ATOM 2721 N ND1 . HIS A 1 793 ? 130.072 170.097 131.219 1.00 84.43  ? 809 HIS A ND1 1 
ATOM 2722 C CD2 . HIS A 1 793 ? 128.287 169.180 132.079 1.00 84.43  ? 809 HIS A CD2 1 
ATOM 2723 C CE1 . HIS A 1 793 ? 129.205 169.934 130.236 1.00 84.45  ? 809 HIS A CE1 1 
ATOM 2724 N NE2 . HIS A 1 793 ? 128.113 169.379 130.731 1.00 84.72  ? 809 HIS A NE2 1 
ATOM 2725 N N   . SER A 1 794 ? 130.751 169.508 136.869 1.00 90.85  ? 810 SER A N   1 
ATOM 2726 C CA  . SER A 1 794 ? 131.610 169.222 138.012 1.00 90.15  ? 810 SER A CA  1 
ATOM 2727 C C   . SER A 1 794 ? 131.053 168.081 138.851 1.00 89.61  ? 810 SER A C   1 
ATOM 2728 O O   . SER A 1 794 ? 131.813 167.219 139.307 1.00 90.38  ? 810 SER A O   1 
ATOM 2729 C CB  . SER A 1 794 ? 131.778 170.476 138.870 1.00 91.39  ? 810 SER A CB  1 
ATOM 2730 O OG  . SER A 1 794 ? 130.527 170.935 139.351 1.00 91.42  ? 810 SER A OG  1 
ATOM 2731 N N   . LYS A 1 795 ? 129.736 168.058 139.065 1.00 84.94  ? 811 LYS A N   1 
ATOM 2732 C CA  . LYS A 1 795 ? 129.117 166.967 139.807 1.00 86.46  ? 811 LYS A CA  1 
ATOM 2733 C C   . LYS A 1 795 ? 129.067 165.676 139.001 1.00 86.17  ? 811 LYS A C   1 
ATOM 2734 O O   . LYS A 1 795 ? 128.843 164.608 139.581 1.00 83.68  ? 811 LYS A O   1 
ATOM 2735 C CB  . LYS A 1 795 ? 127.705 167.366 140.238 1.00 83.49  ? 811 LYS A CB  1 
ATOM 2736 C CG  . LYS A 1 795 ? 127.658 168.567 141.167 1.00 84.29  ? 811 LYS A CG  1 
ATOM 2737 C CD  . LYS A 1 795 ? 126.228 168.974 141.476 1.00 87.96  ? 811 LYS A CD  1 
ATOM 2738 C CE  . LYS A 1 795 ? 126.178 170.183 142.396 1.00 87.33  ? 811 LYS A CE  1 
ATOM 2739 N NZ  . LYS A 1 795 ? 126.772 169.899 143.732 1.00 86.75  ? 811 LYS A NZ  1 
ATOM 2740 N N   . GLY A 1 796 ? 129.269 165.746 137.688 1.00 88.34  ? 812 GLY A N   1 
ATOM 2741 C CA  . GLY A 1 796 ? 129.258 164.570 136.845 1.00 87.04  ? 812 GLY A CA  1 
ATOM 2742 C C   . GLY A 1 796 ? 127.958 164.302 136.122 1.00 88.48  ? 812 GLY A C   1 
ATOM 2743 O O   . GLY A 1 796 ? 127.828 163.244 135.494 1.00 85.71  ? 812 GLY A O   1 
ATOM 2744 N N   . LEU A 1 797 ? 126.994 165.216 136.187 1.00 78.58  ? 813 LEU A N   1 
ATOM 2745 C CA  . LEU A 1 797 ? 125.707 165.011 135.542 1.00 71.21  ? 813 LEU A CA  1 
ATOM 2746 C C   . LEU A 1 797 ? 125.678 165.659 134.163 1.00 73.23  ? 813 LEU A C   1 
ATOM 2747 O O   . LEU A 1 797 ? 126.318 166.686 133.919 1.00 79.82  ? 813 LEU A O   1 
ATOM 2748 C CB  . LEU A 1 797 ? 124.578 165.583 136.400 1.00 71.82  ? 813 LEU A CB  1 
ATOM 2749 C CG  . LEU A 1 797 ? 124.123 164.742 137.594 1.00 72.81  ? 813 LEU A CG  1 
ATOM 2750 C CD1 . LEU A 1 797 ? 125.270 164.487 138.560 1.00 76.65  ? 813 LEU A CD1 1 
ATOM 2751 C CD2 . LEU A 1 797 ? 122.963 165.423 138.305 1.00 73.41  ? 813 LEU A CD2 1 
ATOM 2752 N N   . LYS A 1 798 ? 124.926 165.042 133.258 1.00 73.82  ? 814 LYS A N   1 
ATOM 2753 C CA  . LYS A 1 798 ? 124.705 165.593 131.931 1.00 78.68  ? 814 LYS A CA  1 
ATOM 2754 C C   . LYS A 1 798 ? 123.434 166.435 131.921 1.00 80.81  ? 814 LYS A C   1 
ATOM 2755 O O   . LYS A 1 798 ? 122.453 166.123 132.601 1.00 81.23  ? 814 LYS A O   1 
ATOM 2756 C CB  . LYS A 1 798 ? 124.601 164.476 130.891 1.00 78.11  ? 814 LYS A CB  1 
ATOM 2757 C CG  . LYS A 1 798 ? 125.854 163.622 130.764 1.00 76.10  ? 814 LYS A CG  1 
ATOM 2758 C CD  . LYS A 1 798 ? 127.008 164.405 130.159 1.00 78.90  ? 814 LYS A CD  1 
ATOM 2759 C CE  . LYS A 1 798 ? 128.235 163.528 129.965 1.00 75.51  ? 814 LYS A CE  1 
ATOM 2760 N NZ  . LYS A 1 798 ? 128.764 163.007 131.256 1.00 76.99  ? 814 LYS A NZ  1 
ATOM 2761 N N   . VAL A 1 799 ? 123.461 167.510 131.138 1.00 84.64  ? 815 VAL A N   1 
ATOM 2762 C CA  . VAL A 1 799 ? 122.363 168.468 131.066 1.00 85.13  ? 815 VAL A CA  1 
ATOM 2763 C C   . VAL A 1 799 ? 121.771 168.411 129.665 1.00 86.23  ? 815 VAL A C   1 
ATOM 2764 O O   . VAL A 1 799 ? 122.488 168.580 128.671 1.00 87.13  ? 815 VAL A O   1 
ATOM 2765 C CB  . VAL A 1 799 ? 122.829 169.892 131.406 1.00 86.11  ? 815 VAL A CB  1 
ATOM 2766 C CG1 . VAL A 1 799 ? 121.655 170.860 131.367 1.00 88.92  ? 815 VAL A CG1 1 
ATOM 2767 C CG2 . VAL A 1 799 ? 123.502 169.918 132.767 1.00 84.90  ? 815 VAL A CG2 1 
ATOM 2768 N N   . HIS A 1 800 ? 120.463 168.174 129.588 1.00 80.18  ? 816 HIS A N   1 
ATOM 2769 C CA  . HIS A 1 800 ? 119.729 168.147 128.329 1.00 79.93  ? 816 HIS A CA  1 
ATOM 2770 C C   . HIS A 1 800 ? 118.627 169.195 128.386 1.00 83.62  ? 816 HIS A C   1 
ATOM 2771 O O   . HIS A 1 800 ? 117.825 169.205 129.327 1.00 84.22  ? 816 HIS A O   1 
ATOM 2772 C CB  . HIS A 1 800 ? 119.134 166.762 128.063 1.00 78.76  ? 816 HIS A CB  1 
ATOM 2773 C CG  . HIS A 1 800 ? 120.157 165.677 127.920 1.00 79.80  ? 816 HIS A CG  1 
ATOM 2774 N ND1 . HIS A 1 800 ? 119.816 164.345 127.827 1.00 81.48  ? 816 HIS A ND1 1 
ATOM 2775 C CD2 . HIS A 1 800 ? 121.508 165.726 127.849 1.00 83.03  ? 816 HIS A CD2 1 
ATOM 2776 C CE1 . HIS A 1 800 ? 120.914 163.619 127.708 1.00 82.82  ? 816 HIS A CE1 1 
ATOM 2777 N NE2 . HIS A 1 800 ? 121.954 164.433 127.719 1.00 83.03  ? 816 HIS A NE2 1 
ATOM 2778 N N   . ALA A 1 801 ? 118.585 170.068 127.384 1.00 91.94  ? 817 ALA A N   1 
ATOM 2779 C CA  . ALA A 1 801 ? 117.554 171.093 127.289 1.00 94.17  ? 817 ALA A CA  1 
ATOM 2780 C C   . ALA A 1 801 ? 116.436 170.593 126.383 1.00 93.43  ? 817 ALA A C   1 
ATOM 2781 O O   . ALA A 1 801 ? 116.696 170.119 125.273 1.00 92.02  ? 817 ALA A O   1 
ATOM 2782 C CB  . ALA A 1 801 ? 118.134 172.398 126.746 1.00 94.02  ? 817 ALA A CB  1 
ATOM 2783 N N   . TRP A 1 802 ? 115.196 170.700 126.853 1.00 82.92  ? 818 TRP A N   1 
ATOM 2784 C CA  . TRP A 1 802 ? 114.051 170.175 126.124 1.00 82.41  ? 818 TRP A CA  1 
ATOM 2785 C C   . TRP A 1 802 ? 113.161 171.310 125.632 1.00 84.89  ? 818 TRP A C   1 
ATOM 2786 O O   . TRP A 1 802 ? 113.073 172.368 126.262 1.00 84.06  ? 818 TRP A O   1 
ATOM 2787 C CB  . TRP A 1 802 ? 113.246 169.197 126.989 1.00 83.31  ? 818 TRP A CB  1 
ATOM 2788 C CG  . TRP A 1 802 ? 112.810 169.726 128.325 1.00 83.36  ? 818 TRP A CG  1 
ATOM 2789 C CD1 . TRP A 1 802 ? 113.610 170.033 129.387 1.00 85.07  ? 818 TRP A CD1 1 
ATOM 2790 C CD2 . TRP A 1 802 ? 111.465 169.980 128.752 1.00 82.37  ? 818 TRP A CD2 1 
ATOM 2791 N NE1 . TRP A 1 802 ? 112.850 170.476 130.441 1.00 83.56  ? 818 TRP A NE1 1 
ATOM 2792 C CE2 . TRP A 1 802 ? 111.530 170.451 130.078 1.00 83.49  ? 818 TRP A CE2 1 
ATOM 2793 C CE3 . TRP A 1 802 ? 110.214 169.859 128.141 1.00 83.95  ? 818 TRP A CE3 1 
ATOM 2794 C CZ2 . TRP A 1 802 ? 110.395 170.803 130.801 1.00 86.06  ? 818 TRP A CZ2 1 
ATOM 2795 C CZ3 . TRP A 1 802 ? 109.086 170.211 128.861 1.00 83.60  ? 818 TRP A CZ3 1 
ATOM 2796 C CH2 . TRP A 1 802 ? 109.185 170.677 130.177 1.00 84.48  ? 818 TRP A CH2 1 
ATOM 2797 N N   . THR A 1 803 ? 112.506 171.077 124.493 1.00 91.97  ? 819 THR A N   1 
ATOM 2798 C CA  . THR A 1 803 ? 111.664 172.079 123.833 1.00 88.45  ? 819 THR A CA  1 
ATOM 2799 C C   . THR A 1 803 ? 112.503 173.229 123.278 1.00 88.33  ? 819 THR A C   1 
ATOM 2800 O O   . THR A 1 803 ? 112.182 174.404 123.463 1.00 88.25  ? 819 THR A O   1 
ATOM 2801 C CB  . THR A 1 803 ? 110.577 172.607 124.775 1.00 89.47  ? 819 THR A CB  1 
ATOM 2802 O OG1 . THR A 1 803 ? 111.176 173.214 125.926 1.00 89.69  ? 819 THR A OG1 1 
ATOM 2803 C CG2 . THR A 1 803 ? 109.663 171.478 125.217 1.00 86.64  ? 819 THR A CG2 1 
ATOM 2804 N N   . VAL A 1 804 ? 113.589 172.884 122.588 1.00 94.06  ? 820 VAL A N   1 
ATOM 2805 C CA  . VAL A 1 804 ? 114.420 173.861 121.888 1.00 94.81  ? 820 VAL A CA  1 
ATOM 2806 C C   . VAL A 1 804 ? 113.995 173.842 120.422 1.00 96.30  ? 820 VAL A C   1 
ATOM 2807 O O   . VAL A 1 804 ? 114.158 172.835 119.732 1.00 96.91  ? 820 VAL A O   1 
ATOM 2808 C CB  . VAL A 1 804 ? 115.912 173.555 122.046 1.00 95.86  ? 820 VAL A CB  1 
ATOM 2809 C CG1 . VAL A 1 804 ? 116.752 174.616 121.345 1.00 95.60  ? 820 VAL A CG1 1 
ATOM 2810 C CG2 . VAL A 1 804 ? 116.277 173.465 123.519 1.00 96.01  ? 820 VAL A CG2 1 
ATOM 2811 N N   . ASN A 1 805 ? 113.447 174.960 119.941 1.00 91.07  ? 821 ASN A N   1 
ATOM 2812 C CA  . ASN A 1 805 ? 112.896 175.035 118.592 1.00 91.42  ? 821 ASN A CA  1 
ATOM 2813 C C   . ASN A 1 805 ? 113.368 176.263 117.822 1.00 92.42  ? 821 ASN A C   1 
ATOM 2814 O O   . ASN A 1 805 ? 112.766 176.602 116.796 1.00 92.01  ? 821 ASN A O   1 
ATOM 2815 C CB  . ASN A 1 805 ? 111.366 175.018 118.651 1.00 89.21  ? 821 ASN A CB  1 
ATOM 2816 C CG  . ASN A 1 805 ? 110.823 173.770 119.320 1.00 89.56  ? 821 ASN A CG  1 
ATOM 2817 O OD1 . ASN A 1 805 ? 111.408 172.692 119.215 1.00 88.37  ? 821 ASN A OD1 1 
ATOM 2818 N ND2 . ASN A 1 805 ? 109.702 173.912 120.016 1.00 88.91  ? 821 ASN A ND2 1 
ATOM 2819 N N   . THR A 1 806 ? 114.420 176.937 118.280 1.00 98.49  ? 822 THR A N   1 
ATOM 2820 C CA  . THR A 1 806 ? 114.975 178.089 117.583 1.00 98.24  ? 822 THR A CA  1 
ATOM 2821 C C   . THR A 1 806 ? 116.481 177.923 117.447 1.00 99.11  ? 822 THR A C   1 
ATOM 2822 O O   . THR A 1 806 ? 117.154 177.437 118.360 1.00 99.84  ? 822 THR A O   1 
ATOM 2823 C CB  . THR A 1 806 ? 114.659 179.400 118.316 1.00 98.03  ? 822 THR A CB  1 
ATOM 2824 O OG1 . THR A 1 806 ? 115.146 179.330 119.662 1.00 98.85  ? 822 THR A OG1 1 
ATOM 2825 C CG2 . THR A 1 806 ? 113.160 179.653 118.333 1.00 95.86  ? 822 THR A CG2 1 
ATOM 2826 N N   . LYS A 1 807 ? 117.006 178.331 116.288 1.00 103.81 ? 823 LYS A N   1 
ATOM 2827 C CA  . LYS A 1 807 ? 118.431 178.156 116.026 1.00 105.32 ? 823 LYS A CA  1 
ATOM 2828 C C   . LYS A 1 807 ? 119.275 179.055 116.920 1.00 105.62 ? 823 LYS A C   1 
ATOM 2829 O O   . LYS A 1 807 ? 120.361 178.660 117.357 1.00 103.48 ? 823 LYS A O   1 
ATOM 2830 C CB  . LYS A 1 807 ? 118.736 178.431 114.554 1.00 105.18 ? 823 LYS A CB  1 
ATOM 2831 C CG  . LYS A 1 807 ? 120.087 177.891 114.104 1.00 106.26 ? 823 LYS A CG  1 
ATOM 2832 C CD  . LYS A 1 807 ? 120.407 178.269 112.667 1.00 106.79 ? 823 LYS A CD  1 
ATOM 2833 C CE  . LYS A 1 807 ? 120.765 179.741 112.542 1.00 107.27 ? 823 LYS A CE  1 
ATOM 2834 N NZ  . LYS A 1 807 ? 121.262 180.078 111.180 1.00 105.92 ? 823 LYS A NZ  1 
ATOM 2835 N N   . GLU A 1 808 ? 118.802 180.273 117.193 1.00 108.77 ? 824 GLU A N   1 
ATOM 2836 C CA  . GLU A 1 808 ? 119.558 181.175 118.059 1.00 107.97 ? 824 GLU A CA  1 
ATOM 2837 C C   . GLU A 1 808 ? 119.659 180.619 119.473 1.00 108.06 ? 824 GLU A C   1 
ATOM 2838 O O   . GLU A 1 808 ? 120.739 180.621 120.078 1.00 108.29 ? 824 GLU A O   1 
ATOM 2839 C CB  . GLU A 1 808 ? 118.907 182.559 118.074 1.00 107.73 ? 824 GLU A CB  1 
ATOM 2840 C CG  . GLU A 1 808 ? 119.079 183.354 116.784 1.00 107.26 ? 824 GLU A CG  1 
ATOM 2841 C CD  . GLU A 1 808 ? 118.288 182.781 115.624 1.00 108.55 ? 824 GLU A CD  1 
ATOM 2842 O OE1 . GLU A 1 808 ? 117.537 181.806 115.837 1.00 109.09 ? 824 GLU A OE1 1 
ATOM 2843 O OE2 . GLU A 1 808 ? 118.417 183.307 114.498 1.00 106.86 ? 824 GLU A OE2 1 
ATOM 2844 N N   . GLU A 1 809 ? 118.542 180.132 120.017 1.00 104.24 ? 825 GLU A N   1 
ATOM 2845 C CA  . GLU A 1 809 ? 118.566 179.538 121.349 1.00 104.86 ? 825 GLU A CA  1 
ATOM 2846 C C   . GLU A 1 809 ? 119.428 178.283 121.364 1.00 103.84 ? 825 GLU A C   1 
ATOM 2847 O O   . GLU A 1 809 ? 120.143 178.018 122.336 1.00 101.97 ? 825 GLU A O   1 
ATOM 2848 C CB  . GLU A 1 809 ? 117.141 179.220 121.805 1.00 103.93 ? 825 GLU A CB  1 
ATOM 2849 C CG  . GLU A 1 809 ? 117.028 178.805 123.265 1.00 106.52 ? 825 GLU A CG  1 
ATOM 2850 C CD  . GLU A 1 809 ? 117.371 179.929 124.223 1.00 107.61 ? 825 GLU A CD  1 
ATOM 2851 O OE1 . GLU A 1 809 ? 117.553 181.074 123.759 1.00 106.66 ? 825 GLU A OE1 1 
ATOM 2852 O OE2 . GLU A 1 809 ? 117.457 179.668 125.441 1.00 107.17 ? 825 GLU A OE2 1 
ATOM 2853 N N   . MET A 1 810 ? 119.363 177.491 120.293 1.00 100.15 ? 826 MET A N   1 
ATOM 2854 C CA  . MET A 1 810 ? 120.191 176.294 120.204 1.00 100.13 ? 826 MET A CA  1 
ATOM 2855 C C   . MET A 1 810 ? 121.672 176.655 120.228 1.00 99.42  ? 826 MET A C   1 
ATOM 2856 O O   . MET A 1 810 ? 122.469 176.016 120.923 1.00 97.83  ? 826 MET A O   1 
ATOM 2857 C CB  . MET A 1 810 ? 119.843 175.521 118.932 1.00 100.61 ? 826 MET A CB  1 
ATOM 2858 C CG  . MET A 1 810 ? 120.489 174.151 118.841 1.00 100.55 ? 826 MET A CG  1 
ATOM 2859 S SD  . MET A 1 810 ? 120.120 173.302 117.294 1.00 101.68 ? 826 MET A SD  1 
ATOM 2860 C CE  . MET A 1 810 ? 118.331 173.247 117.348 1.00 96.51  ? 826 MET A CE  1 
ATOM 2861 N N   . GLN A 1 811 ? 122.057 177.683 119.470 1.00 106.25 ? 827 GLN A N   1 
ATOM 2862 C CA  . GLN A 1 811 ? 123.449 178.124 119.468 1.00 107.71 ? 827 GLN A CA  1 
ATOM 2863 C C   . GLN A 1 811 ? 123.863 178.636 120.840 1.00 107.31 ? 827 GLN A C   1 
ATOM 2864 O O   . GLN A 1 811 ? 124.974 178.357 121.308 1.00 107.39 ? 827 GLN A O   1 
ATOM 2865 C CB  . GLN A 1 811 ? 123.648 179.206 118.404 1.00 107.90 ? 827 GLN A CB  1 
ATOM 2866 C CG  . GLN A 1 811 ? 125.016 179.882 118.414 1.00 106.30 ? 827 GLN A CG  1 
ATOM 2867 C CD  . GLN A 1 811 ? 126.154 178.923 118.124 1.00 106.02 ? 827 GLN A CD  1 
ATOM 2868 O OE1 . GLN A 1 811 ? 125.942 177.727 117.926 1.00 106.15 ? 827 GLN A OE1 1 
ATOM 2869 N NE2 . GLN A 1 811 ? 127.374 179.447 118.092 1.00 105.61 ? 827 GLN A NE2 1 
ATOM 2870 N N   . SER A 1 812 ? 122.985 179.394 121.500 1.00 102.60 ? 828 SER A N   1 
ATOM 2871 C CA  . SER A 1 812 ? 123.301 179.880 122.839 1.00 102.52 ? 828 SER A CA  1 
ATOM 2872 C C   . SER A 1 812 ? 123.518 178.721 123.803 1.00 102.67 ? 828 SER A C   1 
ATOM 2873 O O   . SER A 1 812 ? 124.473 178.725 124.589 1.00 101.02 ? 828 SER A O   1 
ATOM 2874 C CB  . SER A 1 812 ? 122.184 180.795 123.340 1.00 100.84 ? 828 SER A CB  1 
ATOM 2875 O OG  . SER A 1 812 ? 122.022 181.917 122.489 1.00 100.66 ? 828 SER A OG  1 
ATOM 2876 N N   . LEU A 1 813 ? 122.648 177.711 123.750 1.00 98.24  ? 829 LEU A N   1 
ATOM 2877 C CA  . LEU A 1 813 ? 122.799 176.556 124.628 1.00 96.24  ? 829 LEU A CA  1 
ATOM 2878 C C   . LEU A 1 813 ? 124.076 175.786 124.315 1.00 96.03  ? 829 LEU A C   1 
ATOM 2879 O O   . LEU A 1 813 ? 124.759 175.309 125.228 1.00 95.80  ? 829 LEU A O   1 
ATOM 2880 C CB  . LEU A 1 813 ? 121.577 175.646 124.507 1.00 96.36  ? 829 LEU A CB  1 
ATOM 2881 C CG  . LEU A 1 813 ? 120.257 176.252 124.990 1.00 97.03  ? 829 LEU A CG  1 
ATOM 2882 C CD1 . LEU A 1 813 ? 119.092 175.353 124.618 1.00 95.82  ? 829 LEU A CD1 1 
ATOM 2883 C CD2 . LEU A 1 813 ? 120.286 176.499 126.492 1.00 97.63  ? 829 LEU A CD2 1 
ATOM 2884 N N   . ILE A 1 814 ? 124.412 175.650 123.030 1.00 99.20  ? 830 ILE A N   1 
ATOM 2885 C CA  . ILE A 1 814 ? 125.662 174.993 122.659 1.00 99.93  ? 830 ILE A CA  1 
ATOM 2886 C C   . ILE A 1 814 ? 126.845 175.749 123.247 1.00 101.01 ? 830 ILE A C   1 
ATOM 2887 O O   . ILE A 1 814 ? 127.789 175.147 123.772 1.00 100.29 ? 830 ILE A O   1 
ATOM 2888 C CB  . ILE A 1 814 ? 125.770 174.875 121.127 1.00 99.22  ? 830 ILE A CB  1 
ATOM 2889 C CG1 . ILE A 1 814 ? 124.758 173.857 120.590 1.00 97.82  ? 830 ILE A CG1 1 
ATOM 2890 C CG2 . ILE A 1 814 ? 127.188 174.498 120.716 1.00 99.45  ? 830 ILE A CG2 1 
ATOM 2891 C CD1 . ILE A 1 814 ? 125.039 172.417 120.986 1.00 99.22  ? 830 ILE A CD1 1 
ATOM 2892 N N   . GLN A 1 815 ? 126.815 177.081 123.167 1.00 103.64 ? 831 GLN A N   1 
ATOM 2893 C CA  . GLN A 1 815 ? 127.849 177.879 123.815 1.00 104.53 ? 831 GLN A CA  1 
ATOM 2894 C C   . GLN A 1 815 ? 127.867 177.647 125.320 1.00 104.74 ? 831 GLN A C   1 
ATOM 2895 O O   . GLN A 1 815 ? 128.938 177.677 125.937 1.00 103.31 ? 831 GLN A O   1 
ATOM 2896 C CB  . GLN A 1 815 ? 127.639 179.362 123.511 1.00 104.20 ? 831 GLN A CB  1 
ATOM 2897 C CG  . GLN A 1 815 ? 127.867 179.734 122.054 1.00 105.27 ? 831 GLN A CG  1 
ATOM 2898 C CD  . GLN A 1 815 ? 127.698 181.220 121.798 1.00 106.39 ? 831 GLN A CD  1 
ATOM 2899 O OE1 . GLN A 1 815 ? 127.399 181.989 122.712 1.00 106.16 ? 831 GLN A OE1 1 
ATOM 2900 N NE2 . GLN A 1 815 ? 127.889 181.631 120.550 1.00 106.40 ? 831 GLN A NE2 1 
ATOM 2901 N N   . MET A 1 816 ? 126.700 177.414 125.925 1.00 100.82 ? 832 MET A N   1 
ATOM 2902 C CA  . MET A 1 816 ? 126.637 177.096 127.346 1.00 100.67 ? 832 MET A CA  1 
ATOM 2903 C C   . MET A 1 816 ? 127.176 175.707 127.659 1.00 99.58  ? 832 MET A C   1 
ATOM 2904 O O   . MET A 1 816 ? 127.428 175.405 128.831 1.00 99.63  ? 832 MET A O   1 
ATOM 2905 C CB  . MET A 1 816 ? 125.195 177.202 127.848 1.00 99.26  ? 832 MET A CB  1 
ATOM 2906 C CG  . MET A 1 816 ? 124.623 178.608 127.812 1.00 101.27 ? 832 MET A CG  1 
ATOM 2907 S SD  . MET A 1 816 ? 122.876 178.649 128.257 1.00 101.97 ? 832 MET A SD  1 
ATOM 2908 C CE  . MET A 1 816 ? 122.448 180.326 127.801 1.00 99.08  ? 832 MET A CE  1 
ATOM 2909 N N   . GLY A 1 817 ? 127.357 174.860 126.649 1.00 91.77  ? 833 GLY A N   1 
ATOM 2910 C CA  . GLY A 1 817 ? 127.862 173.519 126.863 1.00 92.58  ? 833 GLY A CA  1 
ATOM 2911 C C   . GLY A 1 817 ? 126.809 172.468 127.121 1.00 91.81  ? 833 GLY A C   1 
ATOM 2912 O O   . GLY A 1 817 ? 127.138 171.405 127.660 1.00 87.17  ? 833 GLY A O   1 
ATOM 2913 N N   . VAL A 1 818 ? 125.550 172.726 126.758 1.00 93.11  ? 834 VAL A N   1 
ATOM 2914 C CA  . VAL A 1 818 ? 124.499 171.740 126.974 1.00 90.30  ? 834 VAL A CA  1 
ATOM 2915 C C   . VAL A 1 818 ? 124.820 170.472 126.196 1.00 91.14  ? 834 VAL A C   1 
ATOM 2916 O O   . VAL A 1 818 ? 125.248 170.520 125.035 1.00 91.10  ? 834 VAL A O   1 
ATOM 2917 C CB  . VAL A 1 818 ? 123.134 172.317 126.568 1.00 90.83  ? 834 VAL A CB  1 
ATOM 2918 C CG1 . VAL A 1 818 ? 122.049 171.266 126.723 1.00 91.66  ? 834 VAL A CG1 1 
ATOM 2919 C CG2 . VAL A 1 818 ? 122.810 173.544 127.403 1.00 91.58  ? 834 VAL A CG2 1 
ATOM 2920 N N   . ASP A 1 819 ? 124.611 169.323 126.839 1.00 85.35  ? 835 ASP A N   1 
ATOM 2921 C CA  . ASP A 1 819 ? 125.009 168.040 126.272 1.00 80.94  ? 835 ASP A CA  1 
ATOM 2922 C C   . ASP A 1 819 ? 123.996 167.466 125.289 1.00 83.68  ? 835 ASP A C   1 
ATOM 2923 O O   . ASP A 1 819 ? 124.342 166.538 124.550 1.00 87.13  ? 835 ASP A O   1 
ATOM 2924 C CB  . ASP A 1 819 ? 125.249 167.030 127.396 1.00 81.81  ? 835 ASP A CB  1 
ATOM 2925 C CG  . ASP A 1 819 ? 126.349 167.464 128.344 1.00 84.95  ? 835 ASP A CG  1 
ATOM 2926 O OD1 . ASP A 1 819 ? 127.322 168.093 127.879 1.00 87.38  ? 835 ASP A OD1 1 
ATOM 2927 O OD2 . ASP A 1 819 ? 126.239 167.179 129.555 1.00 83.90  ? 835 ASP A OD2 1 
ATOM 2928 N N   . GLY A 1 820 ? 122.773 167.975 125.255 1.00 91.31  ? 836 GLY A N   1 
ATOM 2929 C CA  . GLY A 1 820 ? 121.783 167.450 124.333 1.00 92.17  ? 836 GLY A CA  1 
ATOM 2930 C C   . GLY A 1 820 ? 120.549 168.324 124.309 1.00 92.80  ? 836 GLY A C   1 
ATOM 2931 O O   . GLY A 1 820 ? 120.293 169.106 125.232 1.00 93.09  ? 836 GLY A O   1 
ATOM 2932 N N   . PHE A 1 821 ? 119.781 168.169 123.231 1.00 92.30  ? 837 PHE A N   1 
ATOM 2933 C CA  . PHE A 1 821 ? 118.572 168.947 123.002 1.00 89.42  ? 837 PHE A CA  1 
ATOM 2934 C C   . PHE A 1 821 ? 117.436 168.033 122.570 1.00 90.27  ? 837 PHE A C   1 
ATOM 2935 O O   . PHE A 1 821 ? 117.653 167.062 121.839 1.00 93.48  ? 837 PHE A O   1 
ATOM 2936 C CB  . PHE A 1 821 ? 118.788 170.017 121.922 1.00 89.68  ? 837 PHE A CB  1 
ATOM 2937 C CG  . PHE A 1 821 ? 119.894 170.984 122.230 1.00 89.05  ? 837 PHE A CG  1 
ATOM 2938 C CD1 . PHE A 1 821 ? 120.081 171.465 123.513 1.00 91.97  ? 837 PHE A CD1 1 
ATOM 2939 C CD2 . PHE A 1 821 ? 120.747 171.413 121.228 1.00 88.66  ? 837 PHE A CD2 1 
ATOM 2940 C CE1 . PHE A 1 821 ? 121.099 172.355 123.791 1.00 93.22  ? 837 PHE A CE1 1 
ATOM 2941 C CE2 . PHE A 1 821 ? 121.766 172.303 121.501 1.00 91.42  ? 837 PHE A CE2 1 
ATOM 2942 C CZ  . PHE A 1 821 ? 121.943 172.774 122.784 1.00 92.15  ? 837 PHE A CZ  1 
ATOM 2943 N N   . PHE A 1 822 ? 116.225 168.349 123.024 1.00 77.68  ? 838 PHE A N   1 
ATOM 2944 C CA  . PHE A 1 822 ? 115.006 167.745 122.491 1.00 80.51  ? 838 PHE A CA  1 
ATOM 2945 C C   . PHE A 1 822 ? 114.372 168.761 121.550 1.00 84.46  ? 838 PHE A C   1 
ATOM 2946 O O   . PHE A 1 822 ? 113.634 169.650 121.987 1.00 83.96  ? 838 PHE A O   1 
ATOM 2947 C CB  . PHE A 1 822 ? 114.042 167.355 123.608 1.00 80.70  ? 838 PHE A CB  1 
ATOM 2948 C CG  . PHE A 1 822 ? 114.625 166.405 124.616 1.00 82.15  ? 838 PHE A CG  1 
ATOM 2949 C CD1 . PHE A 1 822 ? 115.471 166.861 125.612 1.00 84.00  ? 838 PHE A CD1 1 
ATOM 2950 C CD2 . PHE A 1 822 ? 114.312 165.057 124.577 1.00 80.70  ? 838 PHE A CD2 1 
ATOM 2951 C CE1 . PHE A 1 822 ? 116.002 165.990 126.542 1.00 83.98  ? 838 PHE A CE1 1 
ATOM 2952 C CE2 . PHE A 1 822 ? 114.841 164.181 125.505 1.00 79.86  ? 838 PHE A CE2 1 
ATOM 2953 C CZ  . PHE A 1 822 ? 115.686 164.648 126.489 1.00 81.25  ? 838 PHE A CZ  1 
ATOM 2954 N N   . THR A 1 823 ? 114.657 168.632 120.258 1.00 93.86  ? 839 THR A N   1 
ATOM 2955 C CA  . THR A 1 823 ? 114.270 169.620 119.262 1.00 89.52  ? 839 THR A CA  1 
ATOM 2956 C C   . THR A 1 823 ? 113.143 169.077 118.398 1.00 88.01  ? 839 THR A C   1 
ATOM 2957 O O   . THR A 1 823 ? 113.255 167.980 117.840 1.00 91.13  ? 839 THR A O   1 
ATOM 2958 C CB  . THR A 1 823 ? 115.462 170.000 118.380 1.00 92.21  ? 839 THR A CB  1 
ATOM 2959 O OG1 . THR A 1 823 ? 115.930 168.843 117.676 1.00 93.68  ? 839 THR A OG1 1 
ATOM 2960 C CG2 . THR A 1 823 ? 116.591 170.565 119.224 1.00 90.90  ? 839 THR A CG2 1 
ATOM 2961 N N   . ASN A 1 824 ? 112.061 169.849 118.289 1.00 86.49  ? 840 ASN A N   1 
ATOM 2962 C CA  . ASN A 1 824 ? 110.994 169.504 117.358 1.00 87.90  ? 840 ASN A CA  1 
ATOM 2963 C C   . ASN A 1 824 ? 111.436 169.690 115.914 1.00 87.80  ? 840 ASN A C   1 
ATOM 2964 O O   . ASN A 1 824 ? 110.969 168.966 115.027 1.00 84.39  ? 840 ASN A O   1 
ATOM 2965 C CB  . ASN A 1 824 ? 109.755 170.352 117.646 1.00 88.36  ? 840 ASN A CB  1 
ATOM 2966 C CG  . ASN A 1 824 ? 108.542 169.898 116.860 1.00 88.66  ? 840 ASN A CG  1 
ATOM 2967 O OD1 . ASN A 1 824 ? 108.518 168.793 116.317 1.00 88.12  ? 840 ASN A OD1 1 
ATOM 2968 N ND2 . ASN A 1 824 ? 107.525 170.748 116.800 1.00 87.19  ? 840 ASN A ND2 1 
ATOM 2969 N N   . TYR A 1 825 ? 112.327 170.647 115.662 1.00 97.99  ? 841 TYR A N   1 
ATOM 2970 C CA  . TYR A 1 825 ? 112.935 170.855 114.354 1.00 99.90  ? 841 TYR A CA  1 
ATOM 2971 C C   . TYR A 1 825 ? 114.401 170.460 114.453 1.00 100.13 ? 841 TYR A C   1 
ATOM 2972 O O   . TYR A 1 825 ? 115.130 170.980 115.304 1.00 99.45  ? 841 TYR A O   1 
ATOM 2973 C CB  . TYR A 1 825 ? 112.790 172.309 113.904 1.00 99.12  ? 841 TYR A CB  1 
ATOM 2974 C CG  . TYR A 1 825 ? 111.389 172.855 114.063 1.00 99.06  ? 841 TYR A CG  1 
ATOM 2975 C CD1 . TYR A 1 825 ? 110.422 172.637 113.090 1.00 98.23  ? 841 TYR A CD1 1 
ATOM 2976 C CD2 . TYR A 1 825 ? 111.033 173.588 115.187 1.00 98.58  ? 841 TYR A CD2 1 
ATOM 2977 C CE1 . TYR A 1 825 ? 109.140 173.133 113.233 1.00 97.91  ? 841 TYR A CE1 1 
ATOM 2978 C CE2 . TYR A 1 825 ? 109.755 174.088 115.339 1.00 99.00  ? 841 TYR A CE2 1 
ATOM 2979 C CZ  . TYR A 1 825 ? 108.813 173.858 114.359 1.00 98.59  ? 841 TYR A CZ  1 
ATOM 2980 O OH  . TYR A 1 825 ? 107.539 174.355 114.507 1.00 97.49  ? 841 TYR A OH  1 
ATOM 2981 N N   . LEU A 1 826 ? 114.830 169.548 113.583 1.00 99.91  ? 842 LEU A N   1 
ATOM 2982 C CA  . LEU A 1 826 ? 116.132 168.905 113.712 1.00 98.42  ? 842 LEU A CA  1 
ATOM 2983 C C   . LEU A 1 826 ? 117.207 169.547 112.843 1.00 98.11  ? 842 LEU A C   1 
ATOM 2984 O O   . LEU A 1 826 ? 118.348 169.698 113.290 1.00 95.66  ? 842 LEU A O   1 
ATOM 2985 C CB  . LEU A 1 826 ? 116.014 167.417 113.363 1.00 97.72  ? 842 LEU A CB  1 
ATOM 2986 C CG  . LEU A 1 826 ? 115.339 166.518 114.404 1.00 96.76  ? 842 LEU A CG  1 
ATOM 2987 C CD1 . LEU A 1 826 ? 113.945 167.013 114.762 1.00 96.43  ? 842 LEU A CD1 1 
ATOM 2988 C CD2 . LEU A 1 826 ? 115.277 165.089 113.895 1.00 96.93  ? 842 LEU A CD2 1 
ATOM 2989 N N   . ASP A 1 827 ? 116.872 169.933 111.611 1.00 104.78 ? 843 ASP A N   1 
ATOM 2990 C CA  . ASP A 1 827 ? 117.880 170.443 110.689 1.00 104.36 ? 843 ASP A CA  1 
ATOM 2991 C C   . ASP A 1 827 ? 118.520 171.741 111.164 1.00 107.16 ? 843 ASP A C   1 
ATOM 2992 O O   . ASP A 1 827 ? 119.585 172.104 110.654 1.00 107.37 ? 843 ASP A O   1 
ATOM 2993 C CB  . ASP A 1 827 ? 117.268 170.654 109.303 1.00 105.73 ? 843 ASP A CB  1 
ATOM 2994 C CG  . ASP A 1 827 ? 116.078 171.589 109.329 1.00 106.00 ? 843 ASP A CG  1 
ATOM 2995 O OD1 . ASP A 1 827 ? 115.267 171.492 110.274 1.00 106.72 ? 843 ASP A OD1 1 
ATOM 2996 O OD2 . ASP A 1 827 ? 115.953 172.421 108.407 1.00 104.36 ? 843 ASP A OD2 1 
ATOM 2997 N N   . GLU A 1 828 ? 117.906 172.447 112.117 1.00 105.76 ? 844 GLU A N   1 
ATOM 2998 C CA  . GLU A 1 828 ? 118.515 173.669 112.631 1.00 105.07 ? 844 GLU A CA  1 
ATOM 2999 C C   . GLU A 1 828 ? 119.873 173.393 113.261 1.00 105.00 ? 844 GLU A C   1 
ATOM 3000 O O   . GLU A 1 828 ? 120.755 174.259 113.243 1.00 102.98 ? 844 GLU A O   1 
ATOM 3001 C CB  . GLU A 1 828 ? 117.588 174.336 113.648 1.00 101.97 ? 844 GLU A CB  1 
ATOM 3002 C CG  . GLU A 1 828 ? 116.504 175.202 113.026 1.00 102.97 ? 844 GLU A CG  1 
ATOM 3003 C CD  . GLU A 1 828 ? 115.564 174.414 112.137 1.00 104.60 ? 844 GLU A CD  1 
ATOM 3004 O OE1 . GLU A 1 828 ? 115.590 173.168 112.201 1.00 102.70 ? 844 GLU A OE1 1 
ATOM 3005 O OE2 . GLU A 1 828 ? 114.801 175.042 111.372 1.00 105.89 ? 844 GLU A OE2 1 
ATOM 3006 N N   . TYR A 1 829 ? 120.061 172.198 113.825 1.00 98.62  ? 845 TYR A N   1 
ATOM 3007 C CA  . TYR A 1 829 ? 121.363 171.841 114.376 1.00 96.71  ? 845 TYR A CA  1 
ATOM 3008 C C   . TYR A 1 829 ? 122.443 171.852 113.305 1.00 98.03  ? 845 TYR A C   1 
ATOM 3009 O O   . TYR A 1 829 ? 123.588 172.226 113.585 1.00 96.28  ? 845 TYR A O   1 
ATOM 3010 C CB  . TYR A 1 829 ? 121.286 170.467 115.043 1.00 94.52  ? 845 TYR A CB  1 
ATOM 3011 C CG  . TYR A 1 829 ? 122.619 169.936 115.518 1.00 95.36  ? 845 TYR A CG  1 
ATOM 3012 C CD1 . TYR A 1 829 ? 123.205 170.419 116.680 1.00 92.90  ? 845 TYR A CD1 1 
ATOM 3013 C CD2 . TYR A 1 829 ? 123.287 168.947 114.810 1.00 96.71  ? 845 TYR A CD2 1 
ATOM 3014 C CE1 . TYR A 1 829 ? 124.423 169.935 117.120 1.00 93.92  ? 845 TYR A CE1 1 
ATOM 3015 C CE2 . TYR A 1 829 ? 124.505 168.456 115.242 1.00 96.62  ? 845 TYR A CE2 1 
ATOM 3016 C CZ  . TYR A 1 829 ? 125.067 168.954 116.398 1.00 96.41  ? 845 TYR A CZ  1 
ATOM 3017 O OH  . TYR A 1 829 ? 126.279 168.469 116.833 1.00 96.23  ? 845 TYR A OH  1 
ATOM 3018 N N   . LYS A 1 830 ? 122.103 171.453 112.080 1.00 107.02 ? 846 LYS A N   1 
ATOM 3019 C CA  . LYS A 1 830 ? 123.059 171.500 110.981 1.00 108.31 ? 846 LYS A CA  1 
ATOM 3020 C C   . LYS A 1 830 ? 123.305 172.923 110.500 1.00 108.85 ? 846 LYS A C   1 
ATOM 3021 O O   . LYS A 1 830 ? 124.359 173.202 109.918 1.00 106.78 ? 846 LYS A O   1 
ATOM 3022 C CB  . LYS A 1 830 ? 122.562 170.641 109.817 1.00 108.80 ? 846 LYS A CB  1 
ATOM 3023 C CG  . LYS A 1 830 ? 122.314 169.188 110.182 1.00 107.70 ? 846 LYS A CG  1 
ATOM 3024 C CD  . LYS A 1 830 ? 121.702 168.425 109.020 1.00 107.13 ? 846 LYS A CD  1 
ATOM 3025 C CE  . LYS A 1 830 ? 121.438 166.973 109.382 1.00 107.32 ? 846 LYS A CE  1 
ATOM 3026 N NZ  . LYS A 1 830 ? 122.690 166.237 109.712 1.00 107.06 ? 846 LYS A NZ  1 
ATOM 3027 N N   . LYS A 1 831 ? 122.355 173.829 110.732 1.00 106.00 ? 847 LYS A N   1 
ATOM 3028 C CA  . LYS A 1 831 ? 122.483 175.211 110.290 1.00 105.06 ? 847 LYS A CA  1 
ATOM 3029 C C   . LYS A 1 831 ? 123.378 176.045 111.198 1.00 104.75 ? 847 LYS A C   1 
ATOM 3030 O O   . LYS A 1 831 ? 123.674 177.196 110.858 1.00 102.45 ? 847 LYS A O   1 
ATOM 3031 C CB  . LYS A 1 831 ? 121.100 175.861 110.204 1.00 102.74 ? 847 LYS A CB  1 
ATOM 3032 C CG  . LYS A 1 831 ? 120.163 175.192 109.214 1.00 102.61 ? 847 LYS A CG  1 
ATOM 3033 C CD  . LYS A 1 831 ? 118.799 175.860 109.210 1.00 102.60 ? 847 LYS A CD  1 
ATOM 3034 C CE  . LYS A 1 831 ? 117.862 175.200 108.214 1.00 102.18 ? 847 LYS A CE  1 
ATOM 3035 N NZ  . LYS A 1 831 ? 116.509 175.819 108.224 1.00 101.72 ? 847 LYS A NZ  1 
ATOM 3036 N N   . ILE A 1 832 ? 123.809 175.504 112.333 1.00 106.45 ? 848 ILE A N   1 
ATOM 3037 C CA  . ILE A 1 832 ? 124.662 176.241 113.258 1.00 107.10 ? 848 ILE A CA  1 
ATOM 3038 C C   . ILE A 1 832 ? 125.954 176.644 112.555 1.00 104.67 ? 848 ILE A C   1 
ATOM 3039 O O   . ILE A 1 832 ? 126.603 177.619 112.934 1.00 102.87 ? 848 ILE A O   1 
ATOM 3040 C CB  . ILE A 1 832 ? 124.961 175.412 114.524 1.00 106.78 ? 848 ILE A CB  1 
ATOM 3041 C CG1 . ILE A 1 832 ? 123.658 175.059 115.248 1.00 106.25 ? 848 ILE A CG1 1 
ATOM 3042 C CG2 . ILE A 1 832 ? 125.903 176.179 115.450 1.00 104.24 ? 848 ILE A CG2 1 
ATOM 3043 C CD1 . ILE A 1 832 ? 123.839 174.117 116.423 1.00 105.66 ? 848 ILE A CD1 1 
ATOM 3044 O OXT . ILE A 1 832 ? 126.378 176.006 111.592 1.00 50.00  ? 848 ILE A OXT 1 
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