data_9ETP
# 
_entry.id   9ETP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ETP         pdb_00009etp 10.2210/pdb9etp/pdb 
WWPDB D_1292136968 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ETP 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cyclin-dependent kinase 2' 34354.770 2   2.7.11.22 ? ? ? 
2 polymer     man Cyclin-A2                   30817.473 2   ?         ? ? ? 
3 non-polymer syn 4-bromo-1H-pyrazole         146.973   13  ?         ? ? ? 
4 water       nat water                       18.015    414 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cell division protein kinase 2,p33 protein kinase' 
2 Cyclin-A                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
2 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
B,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 4-bromo-1H-pyrazole BYZ 
4 water               HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   SER n 
1 5   MET n 
1 6   GLU n 
1 7   ASN n 
1 8   PHE n 
1 9   GLN n 
1 10  LYS n 
1 11  VAL n 
1 12  GLU n 
1 13  LYS n 
1 14  ILE n 
1 15  GLY n 
1 16  GLU n 
1 17  GLY n 
1 18  THR n 
1 19  TYR n 
1 20  GLY n 
1 21  VAL n 
1 22  VAL n 
1 23  TYR n 
1 24  LYS n 
1 25  ALA n 
1 26  ARG n 
1 27  ASN n 
1 28  LYS n 
1 29  LEU n 
1 30  THR n 
1 31  GLY n 
1 32  GLU n 
1 33  VAL n 
1 34  VAL n 
1 35  ALA n 
1 36  LEU n 
1 37  LYS n 
1 38  LYS n 
1 39  ILE n 
1 40  ARG n 
1 41  LEU n 
1 42  ASP n 
1 43  THR n 
1 44  GLU n 
1 45  THR n 
1 46  GLU n 
1 47  GLY n 
1 48  VAL n 
1 49  PRO n 
1 50  SER n 
1 51  THR n 
1 52  ALA n 
1 53  ILE n 
1 54  ARG n 
1 55  GLU n 
1 56  ILE n 
1 57  SER n 
1 58  LEU n 
1 59  LEU n 
1 60  LYS n 
1 61  GLU n 
1 62  LEU n 
1 63  ASN n 
1 64  HIS n 
1 65  PRO n 
1 66  ASN n 
1 67  ILE n 
1 68  VAL n 
1 69  LYS n 
1 70  LEU n 
1 71  LEU n 
1 72  ASP n 
1 73  VAL n 
1 74  ILE n 
1 75  HIS n 
1 76  THR n 
1 77  GLU n 
1 78  ASN n 
1 79  LYS n 
1 80  LEU n 
1 81  TYR n 
1 82  LEU n 
1 83  VAL n 
1 84  PHE n 
1 85  GLU n 
1 86  PHE n 
1 87  LEU n 
1 88  HIS n 
1 89  GLN n 
1 90  ASP n 
1 91  LEU n 
1 92  LYS n 
1 93  LYS n 
1 94  PHE n 
1 95  MET n 
1 96  ASP n 
1 97  ALA n 
1 98  SER n 
1 99  ALA n 
1 100 LEU n 
1 101 THR n 
1 102 GLY n 
1 103 ILE n 
1 104 PRO n 
1 105 LEU n 
1 106 PRO n 
1 107 LEU n 
1 108 ILE n 
1 109 LYS n 
1 110 SER n 
1 111 TYR n 
1 112 LEU n 
1 113 PHE n 
1 114 GLN n 
1 115 LEU n 
1 116 LEU n 
1 117 GLN n 
1 118 GLY n 
1 119 LEU n 
1 120 ALA n 
1 121 PHE n 
1 122 CYS n 
1 123 HIS n 
1 124 SER n 
1 125 HIS n 
1 126 ARG n 
1 127 VAL n 
1 128 LEU n 
1 129 HIS n 
1 130 ARG n 
1 131 ASP n 
1 132 LEU n 
1 133 LYS n 
1 134 PRO n 
1 135 GLN n 
1 136 ASN n 
1 137 LEU n 
1 138 LEU n 
1 139 ILE n 
1 140 ASN n 
1 141 THR n 
1 142 GLU n 
1 143 GLY n 
1 144 ALA n 
1 145 ILE n 
1 146 LYS n 
1 147 LEU n 
1 148 ALA n 
1 149 ASP n 
1 150 PHE n 
1 151 GLY n 
1 152 LEU n 
1 153 ALA n 
1 154 ARG n 
1 155 ALA n 
1 156 PHE n 
1 157 GLY n 
1 158 VAL n 
1 159 PRO n 
1 160 VAL n 
1 161 ARG n 
1 162 THR n 
1 163 TYR n 
1 164 TPO n 
1 165 HIS n 
1 166 GLU n 
1 167 VAL n 
1 168 VAL n 
1 169 THR n 
1 170 LEU n 
1 171 TRP n 
1 172 TYR n 
1 173 ARG n 
1 174 ALA n 
1 175 PRO n 
1 176 GLU n 
1 177 ILE n 
1 178 LEU n 
1 179 LEU n 
1 180 GLY n 
1 181 CYS n 
1 182 LYS n 
1 183 TYR n 
1 184 TYR n 
1 185 SER n 
1 186 THR n 
1 187 ALA n 
1 188 VAL n 
1 189 ASP n 
1 190 ILE n 
1 191 TRP n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 CYS n 
1 196 ILE n 
1 197 PHE n 
1 198 ALA n 
1 199 GLU n 
1 200 MET n 
1 201 VAL n 
1 202 THR n 
1 203 ARG n 
1 204 ARG n 
1 205 ALA n 
1 206 LEU n 
1 207 PHE n 
1 208 PRO n 
1 209 GLY n 
1 210 ASP n 
1 211 SER n 
1 212 GLU n 
1 213 ILE n 
1 214 ASP n 
1 215 GLN n 
1 216 LEU n 
1 217 PHE n 
1 218 ARG n 
1 219 ILE n 
1 220 PHE n 
1 221 ARG n 
1 222 THR n 
1 223 LEU n 
1 224 GLY n 
1 225 THR n 
1 226 PRO n 
1 227 ASP n 
1 228 GLU n 
1 229 VAL n 
1 230 VAL n 
1 231 TRP n 
1 232 PRO n 
1 233 GLY n 
1 234 VAL n 
1 235 THR n 
1 236 SER n 
1 237 MET n 
1 238 PRO n 
1 239 ASP n 
1 240 TYR n 
1 241 LYS n 
1 242 PRO n 
1 243 SER n 
1 244 PHE n 
1 245 PRO n 
1 246 LYS n 
1 247 TRP n 
1 248 ALA n 
1 249 ARG n 
1 250 GLN n 
1 251 ASP n 
1 252 PHE n 
1 253 SER n 
1 254 LYS n 
1 255 VAL n 
1 256 VAL n 
1 257 PRO n 
1 258 PRO n 
1 259 LEU n 
1 260 ASP n 
1 261 GLU n 
1 262 ASP n 
1 263 GLY n 
1 264 ARG n 
1 265 SER n 
1 266 LEU n 
1 267 LEU n 
1 268 SER n 
1 269 GLN n 
1 270 MET n 
1 271 LEU n 
1 272 HIS n 
1 273 TYR n 
1 274 ASP n 
1 275 PRO n 
1 276 ASN n 
1 277 LYS n 
1 278 ARG n 
1 279 ILE n 
1 280 SER n 
1 281 ALA n 
1 282 LYS n 
1 283 ALA n 
1 284 ALA n 
1 285 LEU n 
1 286 ALA n 
1 287 HIS n 
1 288 PRO n 
1 289 PHE n 
1 290 PHE n 
1 291 GLN n 
1 292 ASP n 
1 293 VAL n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 VAL n 
1 298 PRO n 
1 299 HIS n 
1 300 LEU n 
1 301 ARG n 
1 302 LEU n 
2 1   GLY n 
2 2   VAL n 
2 3   ASN n 
2 4   GLU n 
2 5   VAL n 
2 6   PRO n 
2 7   ASP n 
2 8   TYR n 
2 9   HIS n 
2 10  GLU n 
2 11  ASP n 
2 12  ILE n 
2 13  HIS n 
2 14  THR n 
2 15  TYR n 
2 16  LEU n 
2 17  ARG n 
2 18  GLU n 
2 19  MET n 
2 20  GLU n 
2 21  VAL n 
2 22  LYS n 
2 23  CYS n 
2 24  LYS n 
2 25  PRO n 
2 26  LYS n 
2 27  VAL n 
2 28  GLY n 
2 29  TYR n 
2 30  MET n 
2 31  LYS n 
2 32  LYS n 
2 33  GLN n 
2 34  PRO n 
2 35  ASP n 
2 36  ILE n 
2 37  THR n 
2 38  ASN n 
2 39  SER n 
2 40  MET n 
2 41  ARG n 
2 42  ALA n 
2 43  ILE n 
2 44  LEU n 
2 45  VAL n 
2 46  ASP n 
2 47  TRP n 
2 48  LEU n 
2 49  VAL n 
2 50  GLU n 
2 51  VAL n 
2 52  GLY n 
2 53  GLU n 
2 54  GLU n 
2 55  TYR n 
2 56  LYS n 
2 57  LEU n 
2 58  GLN n 
2 59  ASN n 
2 60  GLU n 
2 61  THR n 
2 62  LEU n 
2 63  HIS n 
2 64  LEU n 
2 65  ALA n 
2 66  VAL n 
2 67  ASN n 
2 68  TYR n 
2 69  ILE n 
2 70  ASP n 
2 71  ARG n 
2 72  PHE n 
2 73  LEU n 
2 74  SER n 
2 75  SER n 
2 76  MET n 
2 77  SER n 
2 78  VAL n 
2 79  LEU n 
2 80  ARG n 
2 81  GLY n 
2 82  LYS n 
2 83  LEU n 
2 84  GLN n 
2 85  LEU n 
2 86  VAL n 
2 87  GLY n 
2 88  THR n 
2 89  ALA n 
2 90  ALA n 
2 91  MET n 
2 92  LEU n 
2 93  LEU n 
2 94  ALA n 
2 95  SER n 
2 96  LYS n 
2 97  PHE n 
2 98  GLU n 
2 99  GLU n 
2 100 ILE n 
2 101 TYR n 
2 102 PRO n 
2 103 PRO n 
2 104 GLU n 
2 105 VAL n 
2 106 ALA n 
2 107 GLU n 
2 108 PHE n 
2 109 VAL n 
2 110 TYR n 
2 111 ILE n 
2 112 THR n 
2 113 ASP n 
2 114 ASP n 
2 115 THR n 
2 116 TYR n 
2 117 THR n 
2 118 LYS n 
2 119 LYS n 
2 120 GLN n 
2 121 VAL n 
2 122 LEU n 
2 123 ARG n 
2 124 MET n 
2 125 GLU n 
2 126 HIS n 
2 127 LEU n 
2 128 VAL n 
2 129 LEU n 
2 130 LYS n 
2 131 VAL n 
2 132 LEU n 
2 133 ALA n 
2 134 PHE n 
2 135 ASP n 
2 136 LEU n 
2 137 ALA n 
2 138 ALA n 
2 139 PRO n 
2 140 THR n 
2 141 ILE n 
2 142 ASN n 
2 143 GLN n 
2 144 PHE n 
2 145 LEU n 
2 146 THR n 
2 147 GLN n 
2 148 TYR n 
2 149 PHE n 
2 150 LEU n 
2 151 HIS n 
2 152 GLN n 
2 153 GLN n 
2 154 PRO n 
2 155 ALA n 
2 156 ASN n 
2 157 CYS n 
2 158 LYS n 
2 159 VAL n 
2 160 GLU n 
2 161 SER n 
2 162 LEU n 
2 163 ALA n 
2 164 MET n 
2 165 PHE n 
2 166 LEU n 
2 167 GLY n 
2 168 GLU n 
2 169 LEU n 
2 170 SER n 
2 171 LEU n 
2 172 ILE n 
2 173 ASP n 
2 174 ALA n 
2 175 ASP n 
2 176 PRO n 
2 177 TYR n 
2 178 LEU n 
2 179 LYS n 
2 180 TYR n 
2 181 LEU n 
2 182 PRO n 
2 183 SER n 
2 184 VAL n 
2 185 ILE n 
2 186 ALA n 
2 187 ALA n 
2 188 ALA n 
2 189 ALA n 
2 190 PHE n 
2 191 HIS n 
2 192 LEU n 
2 193 ALA n 
2 194 LEU n 
2 195 TYR n 
2 196 THR n 
2 197 VAL n 
2 198 THR n 
2 199 GLY n 
2 200 GLN n 
2 201 SER n 
2 202 TRP n 
2 203 PRO n 
2 204 GLU n 
2 205 SER n 
2 206 LEU n 
2 207 VAL n 
2 208 GLN n 
2 209 LYS n 
2 210 THR n 
2 211 GLY n 
2 212 TYR n 
2 213 THR n 
2 214 LEU n 
2 215 GLU n 
2 216 THR n 
2 217 LEU n 
2 218 LYS n 
2 219 PRO n 
2 220 CYS n 
2 221 LEU n 
2 222 LEU n 
2 223 ASP n 
2 224 LEU n 
2 225 HIS n 
2 226 GLN n 
2 227 THR n 
2 228 TYR n 
2 229 LEU n 
2 230 ARG n 
2 231 ALA n 
2 232 PRO n 
2 233 GLN n 
2 234 HIS n 
2 235 ALA n 
2 236 GLN n 
2 237 GLN n 
2 238 SER n 
2 239 ILE n 
2 240 ARG n 
2 241 GLU n 
2 242 LYS n 
2 243 TYR n 
2 244 LYS n 
2 245 ASN n 
2 246 SER n 
2 247 LYS n 
2 248 TYR n 
2 249 HIS n 
2 250 GLY n 
2 251 VAL n 
2 252 SER n 
2 253 LEU n 
2 254 LEU n 
2 255 ASN n 
2 256 PRO n 
2 257 PRO n 
2 258 GLU n 
2 259 THR n 
2 260 LEU n 
2 261 ASN n 
2 262 VAL n 
2 263 HIS n 
2 264 HIS n 
2 265 HIS n 
2 266 HIS n 
2 267 HIS n 
2 268 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?      ? ? ? PGEX6P1 ? ? 
2 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d ? ? ? ?       ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE             ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE            ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE          ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'     ?                  'C4 H7 N O4'     133.103 
BYZ non-polymer         . 4-bromo-1H-pyrazole ?                  'C3 H3 Br N2'    146.973 
CYS 'L-peptide linking' y CYSTEINE            ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE           ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'     ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE             ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE           ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER               ?                  'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE          ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE             ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE              ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE          ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE       ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE             ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE              ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE           ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE    PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN          ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE            ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE              ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -3  ?   ?   ?   A . n 
A 1 2   PRO 2   -2  -2  PRO PRO A . n 
A 1 3   GLY 3   -1  -1  GLY GLY A . n 
A 1 4   SER 4   0   0   SER SER A . n 
A 1 5   MET 5   1   1   MET MET A . n 
A 1 6   GLU 6   2   2   GLU GLU A . n 
A 1 7   ASN 7   3   3   ASN ASN A . n 
A 1 8   PHE 8   4   4   PHE PHE A . n 
A 1 9   GLN 9   5   5   GLN GLN A . n 
A 1 10  LYS 10  6   6   LYS LYS A . n 
A 1 11  VAL 11  7   7   VAL VAL A . n 
A 1 12  GLU 12  8   8   GLU GLU A . n 
A 1 13  LYS 13  9   9   LYS LYS A . n 
A 1 14  ILE 14  10  10  ILE ILE A . n 
A 1 15  GLY 15  11  11  GLY GLY A . n 
A 1 16  GLU 16  12  12  GLU GLU A . n 
A 1 17  GLY 17  13  13  GLY GLY A . n 
A 1 18  THR 18  14  14  THR THR A . n 
A 1 19  TYR 19  15  15  TYR TYR A . n 
A 1 20  GLY 20  16  16  GLY GLY A . n 
A 1 21  VAL 21  17  17  VAL VAL A . n 
A 1 22  VAL 22  18  18  VAL VAL A . n 
A 1 23  TYR 23  19  19  TYR TYR A . n 
A 1 24  LYS 24  20  20  LYS LYS A . n 
A 1 25  ALA 25  21  21  ALA ALA A . n 
A 1 26  ARG 26  22  22  ARG ARG A . n 
A 1 27  ASN 27  23  23  ASN ASN A . n 
A 1 28  LYS 28  24  24  LYS LYS A . n 
A 1 29  LEU 29  25  25  LEU LEU A . n 
A 1 30  THR 30  26  26  THR THR A . n 
A 1 31  GLY 31  27  27  GLY GLY A . n 
A 1 32  GLU 32  28  28  GLU GLU A . n 
A 1 33  VAL 33  29  29  VAL VAL A . n 
A 1 34  VAL 34  30  30  VAL VAL A . n 
A 1 35  ALA 35  31  31  ALA ALA A . n 
A 1 36  LEU 36  32  32  LEU LEU A . n 
A 1 37  LYS 37  33  33  LYS LYS A . n 
A 1 38  LYS 38  34  34  LYS LYS A . n 
A 1 39  ILE 39  35  35  ILE ILE A . n 
A 1 40  ARG 40  36  36  ARG ARG A . n 
A 1 41  LEU 41  37  37  LEU LEU A . n 
A 1 42  ASP 42  38  ?   ?   ?   A . n 
A 1 43  THR 43  39  ?   ?   ?   A . n 
A 1 44  GLU 44  40  ?   ?   ?   A . n 
A 1 45  THR 45  41  41  THR THR A . n 
A 1 46  GLU 46  42  42  GLU GLU A . n 
A 1 47  GLY 47  43  43  GLY GLY A . n 
A 1 48  VAL 48  44  44  VAL VAL A . n 
A 1 49  PRO 49  45  45  PRO PRO A . n 
A 1 50  SER 50  46  46  SER SER A . n 
A 1 51  THR 51  47  47  THR THR A . n 
A 1 52  ALA 52  48  48  ALA ALA A . n 
A 1 53  ILE 53  49  49  ILE ILE A . n 
A 1 54  ARG 54  50  50  ARG ARG A . n 
A 1 55  GLU 55  51  51  GLU GLU A . n 
A 1 56  ILE 56  52  52  ILE ILE A . n 
A 1 57  SER 57  53  53  SER SER A . n 
A 1 58  LEU 58  54  54  LEU LEU A . n 
A 1 59  LEU 59  55  55  LEU LEU A . n 
A 1 60  LYS 60  56  56  LYS LYS A . n 
A 1 61  GLU 61  57  57  GLU GLU A . n 
A 1 62  LEU 62  58  58  LEU LEU A . n 
A 1 63  ASN 63  59  59  ASN ASN A . n 
A 1 64  HIS 64  60  60  HIS HIS A . n 
A 1 65  PRO 65  61  61  PRO PRO A . n 
A 1 66  ASN 66  62  62  ASN ASN A . n 
A 1 67  ILE 67  63  63  ILE ILE A . n 
A 1 68  VAL 68  64  64  VAL VAL A . n 
A 1 69  LYS 69  65  65  LYS LYS A . n 
A 1 70  LEU 70  66  66  LEU LEU A . n 
A 1 71  LEU 71  67  67  LEU LEU A . n 
A 1 72  ASP 72  68  68  ASP ASP A . n 
A 1 73  VAL 73  69  69  VAL VAL A . n 
A 1 74  ILE 74  70  70  ILE ILE A . n 
A 1 75  HIS 75  71  71  HIS HIS A . n 
A 1 76  THR 76  72  72  THR THR A . n 
A 1 77  GLU 77  73  73  GLU GLU A . n 
A 1 78  ASN 78  74  74  ASN ASN A . n 
A 1 79  LYS 79  75  75  LYS LYS A . n 
A 1 80  LEU 80  76  76  LEU LEU A . n 
A 1 81  TYR 81  77  77  TYR TYR A . n 
A 1 82  LEU 82  78  78  LEU LEU A . n 
A 1 83  VAL 83  79  79  VAL VAL A . n 
A 1 84  PHE 84  80  80  PHE PHE A . n 
A 1 85  GLU 85  81  81  GLU GLU A . n 
A 1 86  PHE 86  82  82  PHE PHE A . n 
A 1 87  LEU 87  83  83  LEU LEU A . n 
A 1 88  HIS 88  84  84  HIS HIS A . n 
A 1 89  GLN 89  85  85  GLN GLN A . n 
A 1 90  ASP 90  86  86  ASP ASP A . n 
A 1 91  LEU 91  87  87  LEU LEU A . n 
A 1 92  LYS 92  88  88  LYS LYS A . n 
A 1 93  LYS 93  89  89  LYS LYS A . n 
A 1 94  PHE 94  90  90  PHE PHE A . n 
A 1 95  MET 95  91  91  MET MET A . n 
A 1 96  ASP 96  92  92  ASP ASP A . n 
A 1 97  ALA 97  93  93  ALA ALA A . n 
A 1 98  SER 98  94  94  SER SER A . n 
A 1 99  ALA 99  95  95  ALA ALA A . n 
A 1 100 LEU 100 96  96  LEU LEU A . n 
A 1 101 THR 101 97  97  THR THR A . n 
A 1 102 GLY 102 98  98  GLY GLY A . n 
A 1 103 ILE 103 99  99  ILE ILE A . n 
A 1 104 PRO 104 100 100 PRO PRO A . n 
A 1 105 LEU 105 101 101 LEU LEU A . n 
A 1 106 PRO 106 102 102 PRO PRO A . n 
A 1 107 LEU 107 103 103 LEU LEU A . n 
A 1 108 ILE 108 104 104 ILE ILE A . n 
A 1 109 LYS 109 105 105 LYS LYS A . n 
A 1 110 SER 110 106 106 SER SER A . n 
A 1 111 TYR 111 107 107 TYR TYR A . n 
A 1 112 LEU 112 108 108 LEU LEU A . n 
A 1 113 PHE 113 109 109 PHE PHE A . n 
A 1 114 GLN 114 110 110 GLN GLN A . n 
A 1 115 LEU 115 111 111 LEU LEU A . n 
A 1 116 LEU 116 112 112 LEU LEU A . n 
A 1 117 GLN 117 113 113 GLN GLN A . n 
A 1 118 GLY 118 114 114 GLY GLY A . n 
A 1 119 LEU 119 115 115 LEU LEU A . n 
A 1 120 ALA 120 116 116 ALA ALA A . n 
A 1 121 PHE 121 117 117 PHE PHE A . n 
A 1 122 CYS 122 118 118 CYS CYS A . n 
A 1 123 HIS 123 119 119 HIS HIS A . n 
A 1 124 SER 124 120 120 SER SER A . n 
A 1 125 HIS 125 121 121 HIS HIS A . n 
A 1 126 ARG 126 122 122 ARG ARG A . n 
A 1 127 VAL 127 123 123 VAL VAL A . n 
A 1 128 LEU 128 124 124 LEU LEU A . n 
A 1 129 HIS 129 125 125 HIS HIS A . n 
A 1 130 ARG 130 126 126 ARG ARG A . n 
A 1 131 ASP 131 127 127 ASP ASP A . n 
A 1 132 LEU 132 128 128 LEU LEU A . n 
A 1 133 LYS 133 129 129 LYS LYS A . n 
A 1 134 PRO 134 130 130 PRO PRO A . n 
A 1 135 GLN 135 131 131 GLN GLN A . n 
A 1 136 ASN 136 132 132 ASN ASN A . n 
A 1 137 LEU 137 133 133 LEU LEU A . n 
A 1 138 LEU 138 134 134 LEU LEU A . n 
A 1 139 ILE 139 135 135 ILE ILE A . n 
A 1 140 ASN 140 136 136 ASN ASN A . n 
A 1 141 THR 141 137 137 THR THR A . n 
A 1 142 GLU 142 138 138 GLU GLU A . n 
A 1 143 GLY 143 139 139 GLY GLY A . n 
A 1 144 ALA 144 140 140 ALA ALA A . n 
A 1 145 ILE 145 141 141 ILE ILE A . n 
A 1 146 LYS 146 142 142 LYS LYS A . n 
A 1 147 LEU 147 143 143 LEU LEU A . n 
A 1 148 ALA 148 144 144 ALA ALA A . n 
A 1 149 ASP 149 145 145 ASP ASP A . n 
A 1 150 PHE 150 146 146 PHE PHE A . n 
A 1 151 GLY 151 147 147 GLY GLY A . n 
A 1 152 LEU 152 148 148 LEU LEU A . n 
A 1 153 ALA 153 149 149 ALA ALA A . n 
A 1 154 ARG 154 150 150 ARG ARG A . n 
A 1 155 ALA 155 151 151 ALA ALA A . n 
A 1 156 PHE 156 152 152 PHE PHE A . n 
A 1 157 GLY 157 153 153 GLY GLY A . n 
A 1 158 VAL 158 154 154 VAL VAL A . n 
A 1 159 PRO 159 155 155 PRO PRO A . n 
A 1 160 VAL 160 156 156 VAL VAL A . n 
A 1 161 ARG 161 157 157 ARG ARG A . n 
A 1 162 THR 162 158 158 THR THR A . n 
A 1 163 TYR 163 159 159 TYR TYR A . n 
A 1 164 TPO 164 160 160 TPO TPO A . n 
A 1 165 HIS 165 161 161 HIS HIS A . n 
A 1 166 GLU 166 162 162 GLU GLU A . n 
A 1 167 VAL 167 163 163 VAL VAL A . n 
A 1 168 VAL 168 164 164 VAL VAL A . n 
A 1 169 THR 169 165 165 THR THR A . n 
A 1 170 LEU 170 166 166 LEU LEU A . n 
A 1 171 TRP 171 167 167 TRP TRP A . n 
A 1 172 TYR 172 168 168 TYR TYR A . n 
A 1 173 ARG 173 169 169 ARG ARG A . n 
A 1 174 ALA 174 170 170 ALA ALA A . n 
A 1 175 PRO 175 171 171 PRO PRO A . n 
A 1 176 GLU 176 172 172 GLU GLU A . n 
A 1 177 ILE 177 173 173 ILE ILE A . n 
A 1 178 LEU 178 174 174 LEU LEU A . n 
A 1 179 LEU 179 175 175 LEU LEU A . n 
A 1 180 GLY 180 176 176 GLY GLY A . n 
A 1 181 CYS 181 177 177 CYS CYS A . n 
A 1 182 LYS 182 178 178 LYS LYS A . n 
A 1 183 TYR 183 179 179 TYR TYR A . n 
A 1 184 TYR 184 180 180 TYR TYR A . n 
A 1 185 SER 185 181 181 SER SER A . n 
A 1 186 THR 186 182 182 THR THR A . n 
A 1 187 ALA 187 183 183 ALA ALA A . n 
A 1 188 VAL 188 184 184 VAL VAL A . n 
A 1 189 ASP 189 185 185 ASP ASP A . n 
A 1 190 ILE 190 186 186 ILE ILE A . n 
A 1 191 TRP 191 187 187 TRP TRP A . n 
A 1 192 SER 192 188 188 SER SER A . n 
A 1 193 LEU 193 189 189 LEU LEU A . n 
A 1 194 GLY 194 190 190 GLY GLY A . n 
A 1 195 CYS 195 191 191 CYS CYS A . n 
A 1 196 ILE 196 192 192 ILE ILE A . n 
A 1 197 PHE 197 193 193 PHE PHE A . n 
A 1 198 ALA 198 194 194 ALA ALA A . n 
A 1 199 GLU 199 195 195 GLU GLU A . n 
A 1 200 MET 200 196 196 MET MET A . n 
A 1 201 VAL 201 197 197 VAL VAL A . n 
A 1 202 THR 202 198 198 THR THR A . n 
A 1 203 ARG 203 199 199 ARG ARG A . n 
A 1 204 ARG 204 200 200 ARG ARG A . n 
A 1 205 ALA 205 201 201 ALA ALA A . n 
A 1 206 LEU 206 202 202 LEU LEU A . n 
A 1 207 PHE 207 203 203 PHE PHE A . n 
A 1 208 PRO 208 204 204 PRO PRO A . n 
A 1 209 GLY 209 205 205 GLY GLY A . n 
A 1 210 ASP 210 206 206 ASP ASP A . n 
A 1 211 SER 211 207 207 SER SER A . n 
A 1 212 GLU 212 208 208 GLU GLU A . n 
A 1 213 ILE 213 209 209 ILE ILE A . n 
A 1 214 ASP 214 210 210 ASP ASP A . n 
A 1 215 GLN 215 211 211 GLN GLN A . n 
A 1 216 LEU 216 212 212 LEU LEU A . n 
A 1 217 PHE 217 213 213 PHE PHE A . n 
A 1 218 ARG 218 214 214 ARG ARG A . n 
A 1 219 ILE 219 215 215 ILE ILE A . n 
A 1 220 PHE 220 216 216 PHE PHE A . n 
A 1 221 ARG 221 217 217 ARG ARG A . n 
A 1 222 THR 222 218 218 THR THR A . n 
A 1 223 LEU 223 219 219 LEU LEU A . n 
A 1 224 GLY 224 220 220 GLY GLY A . n 
A 1 225 THR 225 221 221 THR THR A . n 
A 1 226 PRO 226 222 222 PRO PRO A . n 
A 1 227 ASP 227 223 223 ASP ASP A . n 
A 1 228 GLU 228 224 224 GLU GLU A . n 
A 1 229 VAL 229 225 225 VAL VAL A . n 
A 1 230 VAL 230 226 226 VAL VAL A . n 
A 1 231 TRP 231 227 227 TRP TRP A . n 
A 1 232 PRO 232 228 228 PRO PRO A . n 
A 1 233 GLY 233 229 229 GLY GLY A . n 
A 1 234 VAL 234 230 230 VAL VAL A . n 
A 1 235 THR 235 231 231 THR THR A . n 
A 1 236 SER 236 232 232 SER SER A . n 
A 1 237 MET 237 233 233 MET MET A . n 
A 1 238 PRO 238 234 234 PRO PRO A . n 
A 1 239 ASP 239 235 235 ASP ASP A . n 
A 1 240 TYR 240 236 236 TYR TYR A . n 
A 1 241 LYS 241 237 237 LYS LYS A . n 
A 1 242 PRO 242 238 238 PRO PRO A . n 
A 1 243 SER 243 239 239 SER SER A . n 
A 1 244 PHE 244 240 240 PHE PHE A . n 
A 1 245 PRO 245 241 241 PRO PRO A . n 
A 1 246 LYS 246 242 242 LYS LYS A . n 
A 1 247 TRP 247 243 243 TRP TRP A . n 
A 1 248 ALA 248 244 244 ALA ALA A . n 
A 1 249 ARG 249 245 245 ARG ARG A . n 
A 1 250 GLN 250 246 246 GLN GLN A . n 
A 1 251 ASP 251 247 247 ASP ASP A . n 
A 1 252 PHE 252 248 248 PHE PHE A . n 
A 1 253 SER 253 249 249 SER SER A . n 
A 1 254 LYS 254 250 250 LYS LYS A . n 
A 1 255 VAL 255 251 251 VAL VAL A . n 
A 1 256 VAL 256 252 252 VAL VAL A . n 
A 1 257 PRO 257 253 253 PRO PRO A . n 
A 1 258 PRO 258 254 254 PRO PRO A . n 
A 1 259 LEU 259 255 255 LEU LEU A . n 
A 1 260 ASP 260 256 256 ASP ASP A . n 
A 1 261 GLU 261 257 257 GLU GLU A . n 
A 1 262 ASP 262 258 258 ASP ASP A . n 
A 1 263 GLY 263 259 259 GLY GLY A . n 
A 1 264 ARG 264 260 260 ARG ARG A . n 
A 1 265 SER 265 261 261 SER SER A . n 
A 1 266 LEU 266 262 262 LEU LEU A . n 
A 1 267 LEU 267 263 263 LEU LEU A . n 
A 1 268 SER 268 264 264 SER SER A . n 
A 1 269 GLN 269 265 265 GLN GLN A . n 
A 1 270 MET 270 266 266 MET MET A . n 
A 1 271 LEU 271 267 267 LEU LEU A . n 
A 1 272 HIS 272 268 268 HIS HIS A . n 
A 1 273 TYR 273 269 269 TYR TYR A . n 
A 1 274 ASP 274 270 270 ASP ASP A . n 
A 1 275 PRO 275 271 271 PRO PRO A . n 
A 1 276 ASN 276 272 272 ASN ASN A . n 
A 1 277 LYS 277 273 273 LYS LYS A . n 
A 1 278 ARG 278 274 274 ARG ARG A . n 
A 1 279 ILE 279 275 275 ILE ILE A . n 
A 1 280 SER 280 276 276 SER SER A . n 
A 1 281 ALA 281 277 277 ALA ALA A . n 
A 1 282 LYS 282 278 278 LYS LYS A . n 
A 1 283 ALA 283 279 279 ALA ALA A . n 
A 1 284 ALA 284 280 280 ALA ALA A . n 
A 1 285 LEU 285 281 281 LEU LEU A . n 
A 1 286 ALA 286 282 282 ALA ALA A . n 
A 1 287 HIS 287 283 283 HIS HIS A . n 
A 1 288 PRO 288 284 284 PRO PRO A . n 
A 1 289 PHE 289 285 285 PHE PHE A . n 
A 1 290 PHE 290 286 286 PHE PHE A . n 
A 1 291 GLN 291 287 287 GLN GLN A . n 
A 1 292 ASP 292 288 288 ASP ASP A . n 
A 1 293 VAL 293 289 289 VAL VAL A . n 
A 1 294 THR 294 290 290 THR THR A . n 
A 1 295 LYS 295 291 291 LYS LYS A . n 
A 1 296 PRO 296 292 292 PRO PRO A . n 
A 1 297 VAL 297 293 293 VAL VAL A . n 
A 1 298 PRO 298 294 294 PRO PRO A . n 
A 1 299 HIS 299 295 295 HIS HIS A . n 
A 1 300 LEU 300 296 296 LEU LEU A . n 
A 1 301 ARG 301 297 297 ARG ARG A . n 
A 1 302 LEU 302 298 ?   ?   ?   A . n 
B 2 1   GLY 1   171 171 GLY GLY B . n 
B 2 2   VAL 2   172 172 VAL VAL B . n 
B 2 3   ASN 3   173 173 ASN ASN B . n 
B 2 4   GLU 4   174 174 GLU GLU B . n 
B 2 5   VAL 5   175 175 VAL VAL B . n 
B 2 6   PRO 6   176 176 PRO PRO B . n 
B 2 7   ASP 7   177 177 ASP ASP B . n 
B 2 8   TYR 8   178 178 TYR TYR B . n 
B 2 9   HIS 9   179 179 HIS HIS B . n 
B 2 10  GLU 10  180 180 GLU GLU B . n 
B 2 11  ASP 11  181 181 ASP ASP B . n 
B 2 12  ILE 12  182 182 ILE ILE B . n 
B 2 13  HIS 13  183 183 HIS HIS B . n 
B 2 14  THR 14  184 184 THR THR B . n 
B 2 15  TYR 15  185 185 TYR TYR B . n 
B 2 16  LEU 16  186 186 LEU LEU B . n 
B 2 17  ARG 17  187 187 ARG ARG B . n 
B 2 18  GLU 18  188 188 GLU GLU B . n 
B 2 19  MET 19  189 189 MET MET B . n 
B 2 20  GLU 20  190 190 GLU GLU B . n 
B 2 21  VAL 21  191 191 VAL VAL B . n 
B 2 22  LYS 22  192 192 LYS LYS B . n 
B 2 23  CYS 23  193 193 CYS CYS B . n 
B 2 24  LYS 24  194 194 LYS LYS B . n 
B 2 25  PRO 25  195 195 PRO PRO B . n 
B 2 26  LYS 26  196 196 LYS LYS B . n 
B 2 27  VAL 27  197 197 VAL VAL B . n 
B 2 28  GLY 28  198 198 GLY GLY B . n 
B 2 29  TYR 29  199 199 TYR TYR B . n 
B 2 30  MET 30  200 200 MET MET B . n 
B 2 31  LYS 31  201 201 LYS LYS B . n 
B 2 32  LYS 32  202 202 LYS LYS B . n 
B 2 33  GLN 33  203 203 GLN GLN B . n 
B 2 34  PRO 34  204 204 PRO PRO B . n 
B 2 35  ASP 35  205 205 ASP ASP B . n 
B 2 36  ILE 36  206 206 ILE ILE B . n 
B 2 37  THR 37  207 207 THR THR B . n 
B 2 38  ASN 38  208 208 ASN ASN B . n 
B 2 39  SER 39  209 209 SER SER B . n 
B 2 40  MET 40  210 210 MET MET B . n 
B 2 41  ARG 41  211 211 ARG ARG B . n 
B 2 42  ALA 42  212 212 ALA ALA B . n 
B 2 43  ILE 43  213 213 ILE ILE B . n 
B 2 44  LEU 44  214 214 LEU LEU B . n 
B 2 45  VAL 45  215 215 VAL VAL B . n 
B 2 46  ASP 46  216 216 ASP ASP B . n 
B 2 47  TRP 47  217 217 TRP TRP B . n 
B 2 48  LEU 48  218 218 LEU LEU B . n 
B 2 49  VAL 49  219 219 VAL VAL B . n 
B 2 50  GLU 50  220 220 GLU GLU B . n 
B 2 51  VAL 51  221 221 VAL VAL B . n 
B 2 52  GLY 52  222 222 GLY GLY B . n 
B 2 53  GLU 53  223 223 GLU GLU B . n 
B 2 54  GLU 54  224 224 GLU GLU B . n 
B 2 55  TYR 55  225 225 TYR TYR B . n 
B 2 56  LYS 56  226 226 LYS LYS B . n 
B 2 57  LEU 57  227 227 LEU LEU B . n 
B 2 58  GLN 58  228 228 GLN GLN B . n 
B 2 59  ASN 59  229 229 ASN ASN B . n 
B 2 60  GLU 60  230 230 GLU GLU B . n 
B 2 61  THR 61  231 231 THR THR B . n 
B 2 62  LEU 62  232 232 LEU LEU B . n 
B 2 63  HIS 63  233 233 HIS HIS B . n 
B 2 64  LEU 64  234 234 LEU LEU B . n 
B 2 65  ALA 65  235 235 ALA ALA B . n 
B 2 66  VAL 66  236 236 VAL VAL B . n 
B 2 67  ASN 67  237 237 ASN ASN B . n 
B 2 68  TYR 68  238 238 TYR TYR B . n 
B 2 69  ILE 69  239 239 ILE ILE B . n 
B 2 70  ASP 70  240 240 ASP ASP B . n 
B 2 71  ARG 71  241 241 ARG ARG B . n 
B 2 72  PHE 72  242 242 PHE PHE B . n 
B 2 73  LEU 73  243 243 LEU LEU B . n 
B 2 74  SER 74  244 244 SER SER B . n 
B 2 75  SER 75  245 245 SER SER B . n 
B 2 76  MET 76  246 246 MET MET B . n 
B 2 77  SER 77  247 247 SER SER B . n 
B 2 78  VAL 78  248 248 VAL VAL B . n 
B 2 79  LEU 79  249 249 LEU LEU B . n 
B 2 80  ARG 80  250 250 ARG ARG B . n 
B 2 81  GLY 81  251 251 GLY GLY B . n 
B 2 82  LYS 82  252 252 LYS LYS B . n 
B 2 83  LEU 83  253 253 LEU LEU B . n 
B 2 84  GLN 84  254 254 GLN GLN B . n 
B 2 85  LEU 85  255 255 LEU LEU B . n 
B 2 86  VAL 86  256 256 VAL VAL B . n 
B 2 87  GLY 87  257 257 GLY GLY B . n 
B 2 88  THR 88  258 258 THR THR B . n 
B 2 89  ALA 89  259 259 ALA ALA B . n 
B 2 90  ALA 90  260 260 ALA ALA B . n 
B 2 91  MET 91  261 261 MET MET B . n 
B 2 92  LEU 92  262 262 LEU LEU B . n 
B 2 93  LEU 93  263 263 LEU LEU B . n 
B 2 94  ALA 94  264 264 ALA ALA B . n 
B 2 95  SER 95  265 265 SER SER B . n 
B 2 96  LYS 96  266 266 LYS LYS B . n 
B 2 97  PHE 97  267 267 PHE PHE B . n 
B 2 98  GLU 98  268 268 GLU GLU B . n 
B 2 99  GLU 99  269 269 GLU GLU B . n 
B 2 100 ILE 100 270 270 ILE ILE B . n 
B 2 101 TYR 101 271 271 TYR TYR B . n 
B 2 102 PRO 102 272 272 PRO PRO B . n 
B 2 103 PRO 103 273 273 PRO PRO B . n 
B 2 104 GLU 104 274 274 GLU GLU B . n 
B 2 105 VAL 105 275 275 VAL VAL B . n 
B 2 106 ALA 106 276 276 ALA ALA B . n 
B 2 107 GLU 107 277 277 GLU GLU B . n 
B 2 108 PHE 108 278 278 PHE PHE B . n 
B 2 109 VAL 109 279 279 VAL VAL B . n 
B 2 110 TYR 110 280 280 TYR TYR B . n 
B 2 111 ILE 111 281 281 ILE ILE B . n 
B 2 112 THR 112 282 282 THR THR B . n 
B 2 113 ASP 113 283 283 ASP ASP B . n 
B 2 114 ASP 114 284 284 ASP ASP B . n 
B 2 115 THR 115 285 285 THR THR B . n 
B 2 116 TYR 116 286 286 TYR TYR B . n 
B 2 117 THR 117 287 287 THR THR B . n 
B 2 118 LYS 118 288 288 LYS LYS B . n 
B 2 119 LYS 119 289 289 LYS LYS B . n 
B 2 120 GLN 120 290 290 GLN GLN B . n 
B 2 121 VAL 121 291 291 VAL VAL B . n 
B 2 122 LEU 122 292 292 LEU LEU B . n 
B 2 123 ARG 123 293 293 ARG ARG B . n 
B 2 124 MET 124 294 294 MET MET B . n 
B 2 125 GLU 125 295 295 GLU GLU B . n 
B 2 126 HIS 126 296 296 HIS HIS B . n 
B 2 127 LEU 127 297 297 LEU LEU B . n 
B 2 128 VAL 128 298 298 VAL VAL B . n 
B 2 129 LEU 129 299 299 LEU LEU B . n 
B 2 130 LYS 130 300 300 LYS LYS B . n 
B 2 131 VAL 131 301 301 VAL VAL B . n 
B 2 132 LEU 132 302 302 LEU LEU B . n 
B 2 133 ALA 133 303 303 ALA ALA B . n 
B 2 134 PHE 134 304 304 PHE PHE B . n 
B 2 135 ASP 135 305 305 ASP ASP B . n 
B 2 136 LEU 136 306 306 LEU LEU B . n 
B 2 137 ALA 137 307 307 ALA ALA B . n 
B 2 138 ALA 138 308 308 ALA ALA B . n 
B 2 139 PRO 139 309 309 PRO PRO B . n 
B 2 140 THR 140 310 310 THR THR B . n 
B 2 141 ILE 141 311 311 ILE ILE B . n 
B 2 142 ASN 142 312 312 ASN ASN B . n 
B 2 143 GLN 143 313 313 GLN GLN B . n 
B 2 144 PHE 144 314 314 PHE PHE B . n 
B 2 145 LEU 145 315 315 LEU LEU B . n 
B 2 146 THR 146 316 316 THR THR B . n 
B 2 147 GLN 147 317 317 GLN GLN B . n 
B 2 148 TYR 148 318 318 TYR TYR B . n 
B 2 149 PHE 149 319 319 PHE PHE B . n 
B 2 150 LEU 150 320 320 LEU LEU B . n 
B 2 151 HIS 151 321 321 HIS HIS B . n 
B 2 152 GLN 152 322 322 GLN GLN B . n 
B 2 153 GLN 153 323 323 GLN GLN B . n 
B 2 154 PRO 154 324 324 PRO PRO B . n 
B 2 155 ALA 155 325 325 ALA ALA B . n 
B 2 156 ASN 156 326 326 ASN ASN B . n 
B 2 157 CYS 157 327 327 CYS CYS B . n 
B 2 158 LYS 158 328 328 LYS LYS B . n 
B 2 159 VAL 159 329 329 VAL VAL B . n 
B 2 160 GLU 160 330 330 GLU GLU B . n 
B 2 161 SER 161 331 331 SER SER B . n 
B 2 162 LEU 162 332 332 LEU LEU B . n 
B 2 163 ALA 163 333 333 ALA ALA B . n 
B 2 164 MET 164 334 334 MET MET B . n 
B 2 165 PHE 165 335 335 PHE PHE B . n 
B 2 166 LEU 166 336 336 LEU LEU B . n 
B 2 167 GLY 167 337 337 GLY GLY B . n 
B 2 168 GLU 168 338 338 GLU GLU B . n 
B 2 169 LEU 169 339 339 LEU LEU B . n 
B 2 170 SER 170 340 340 SER SER B . n 
B 2 171 LEU 171 341 341 LEU LEU B . n 
B 2 172 ILE 172 342 342 ILE ILE B . n 
B 2 173 ASP 173 343 343 ASP ASP B . n 
B 2 174 ALA 174 344 344 ALA ALA B . n 
B 2 175 ASP 175 345 345 ASP ASP B . n 
B 2 176 PRO 176 346 346 PRO PRO B . n 
B 2 177 TYR 177 347 347 TYR TYR B . n 
B 2 178 LEU 178 348 348 LEU LEU B . n 
B 2 179 LYS 179 349 349 LYS LYS B . n 
B 2 180 TYR 180 350 350 TYR TYR B . n 
B 2 181 LEU 181 351 351 LEU LEU B . n 
B 2 182 PRO 182 352 352 PRO PRO B . n 
B 2 183 SER 183 353 353 SER SER B . n 
B 2 184 VAL 184 354 354 VAL VAL B . n 
B 2 185 ILE 185 355 355 ILE ILE B . n 
B 2 186 ALA 186 356 356 ALA ALA B . n 
B 2 187 ALA 187 357 357 ALA ALA B . n 
B 2 188 ALA 188 358 358 ALA ALA B . n 
B 2 189 ALA 189 359 359 ALA ALA B . n 
B 2 190 PHE 190 360 360 PHE PHE B . n 
B 2 191 HIS 191 361 361 HIS HIS B . n 
B 2 192 LEU 192 362 362 LEU LEU B . n 
B 2 193 ALA 193 363 363 ALA ALA B . n 
B 2 194 LEU 194 364 364 LEU LEU B . n 
B 2 195 TYR 195 365 365 TYR TYR B . n 
B 2 196 THR 196 366 366 THR THR B . n 
B 2 197 VAL 197 367 367 VAL VAL B . n 
B 2 198 THR 198 368 368 THR THR B . n 
B 2 199 GLY 199 369 369 GLY GLY B . n 
B 2 200 GLN 200 370 370 GLN GLN B . n 
B 2 201 SER 201 371 371 SER SER B . n 
B 2 202 TRP 202 372 372 TRP TRP B . n 
B 2 203 PRO 203 373 373 PRO PRO B . n 
B 2 204 GLU 204 374 374 GLU GLU B . n 
B 2 205 SER 205 375 375 SER SER B . n 
B 2 206 LEU 206 376 376 LEU LEU B . n 
B 2 207 VAL 207 377 377 VAL VAL B . n 
B 2 208 GLN 208 378 378 GLN GLN B . n 
B 2 209 LYS 209 379 379 LYS LYS B . n 
B 2 210 THR 210 380 380 THR THR B . n 
B 2 211 GLY 211 381 381 GLY GLY B . n 
B 2 212 TYR 212 382 382 TYR TYR B . n 
B 2 213 THR 213 383 383 THR THR B . n 
B 2 214 LEU 214 384 384 LEU LEU B . n 
B 2 215 GLU 215 385 385 GLU GLU B . n 
B 2 216 THR 216 386 386 THR THR B . n 
B 2 217 LEU 217 387 387 LEU LEU B . n 
B 2 218 LYS 218 388 388 LYS LYS B . n 
B 2 219 PRO 219 389 389 PRO PRO B . n 
B 2 220 CYS 220 390 390 CYS CYS B . n 
B 2 221 LEU 221 391 391 LEU LEU B . n 
B 2 222 LEU 222 392 392 LEU LEU B . n 
B 2 223 ASP 223 393 393 ASP ASP B . n 
B 2 224 LEU 224 394 394 LEU LEU B . n 
B 2 225 HIS 225 395 395 HIS HIS B . n 
B 2 226 GLN 226 396 396 GLN GLN B . n 
B 2 227 THR 227 397 397 THR THR B . n 
B 2 228 TYR 228 398 398 TYR TYR B . n 
B 2 229 LEU 229 399 399 LEU LEU B . n 
B 2 230 ARG 230 400 400 ARG ARG B . n 
B 2 231 ALA 231 401 401 ALA ALA B . n 
B 2 232 PRO 232 402 402 PRO PRO B . n 
B 2 233 GLN 233 403 403 GLN GLN B . n 
B 2 234 HIS 234 404 404 HIS HIS B . n 
B 2 235 ALA 235 405 405 ALA ALA B . n 
B 2 236 GLN 236 406 406 GLN GLN B . n 
B 2 237 GLN 237 407 407 GLN GLN B . n 
B 2 238 SER 238 408 408 SER SER B . n 
B 2 239 ILE 239 409 409 ILE ILE B . n 
B 2 240 ARG 240 410 410 ARG ARG B . n 
B 2 241 GLU 241 411 411 GLU GLU B . n 
B 2 242 LYS 242 412 412 LYS LYS B . n 
B 2 243 TYR 243 413 413 TYR TYR B . n 
B 2 244 LYS 244 414 414 LYS LYS B . n 
B 2 245 ASN 245 415 415 ASN ASN B . n 
B 2 246 SER 246 416 416 SER SER B . n 
B 2 247 LYS 247 417 417 LYS LYS B . n 
B 2 248 TYR 248 418 418 TYR TYR B . n 
B 2 249 HIS 249 419 419 HIS HIS B . n 
B 2 250 GLY 250 420 420 GLY GLY B . n 
B 2 251 VAL 251 421 421 VAL VAL B . n 
B 2 252 SER 252 422 422 SER SER B . n 
B 2 253 LEU 253 423 423 LEU LEU B . n 
B 2 254 LEU 254 424 424 LEU LEU B . n 
B 2 255 ASN 255 425 425 ASN ASN B . n 
B 2 256 PRO 256 426 426 PRO PRO B . n 
B 2 257 PRO 257 427 427 PRO PRO B . n 
B 2 258 GLU 258 428 428 GLU GLU B . n 
B 2 259 THR 259 429 429 THR THR B . n 
B 2 260 LEU 260 430 430 LEU LEU B . n 
B 2 261 ASN 261 431 431 ASN ASN B . n 
B 2 262 VAL 262 432 432 VAL VAL B . n 
B 2 263 HIS 263 433 433 HIS HIS B . n 
B 2 264 HIS 264 434 434 HIS HIS B . n 
B 2 265 HIS 265 435 435 HIS HIS B . n 
B 2 266 HIS 266 436 436 HIS HIS B . n 
B 2 267 HIS 267 437 437 HIS HIS B . n 
B 2 268 HIS 268 438 438 HIS HIS B . n 
C 1 1   GLY 1   -3  ?   ?   ?   C . n 
C 1 2   PRO 2   -2  ?   ?   ?   C . n 
C 1 3   GLY 3   -1  ?   ?   ?   C . n 
C 1 4   SER 4   0   0   SER SER C . n 
C 1 5   MET 5   1   1   MET MET C . n 
C 1 6   GLU 6   2   2   GLU GLU C . n 
C 1 7   ASN 7   3   3   ASN ASN C . n 
C 1 8   PHE 8   4   4   PHE PHE C . n 
C 1 9   GLN 9   5   5   GLN GLN C . n 
C 1 10  LYS 10  6   6   LYS LYS C . n 
C 1 11  VAL 11  7   7   VAL VAL C . n 
C 1 12  GLU 12  8   8   GLU GLU C . n 
C 1 13  LYS 13  9   9   LYS LYS C . n 
C 1 14  ILE 14  10  10  ILE ILE C . n 
C 1 15  GLY 15  11  11  GLY GLY C . n 
C 1 16  GLU 16  12  12  GLU GLU C . n 
C 1 17  GLY 17  13  13  GLY GLY C . n 
C 1 18  THR 18  14  14  THR THR C . n 
C 1 19  TYR 19  15  15  TYR TYR C . n 
C 1 20  GLY 20  16  16  GLY GLY C . n 
C 1 21  VAL 21  17  17  VAL VAL C . n 
C 1 22  VAL 22  18  18  VAL VAL C . n 
C 1 23  TYR 23  19  19  TYR TYR C . n 
C 1 24  LYS 24  20  20  LYS LYS C . n 
C 1 25  ALA 25  21  21  ALA ALA C . n 
C 1 26  ARG 26  22  22  ARG ARG C . n 
C 1 27  ASN 27  23  23  ASN ASN C . n 
C 1 28  LYS 28  24  24  LYS LYS C . n 
C 1 29  LEU 29  25  25  LEU LEU C . n 
C 1 30  THR 30  26  26  THR THR C . n 
C 1 31  GLY 31  27  27  GLY GLY C . n 
C 1 32  GLU 32  28  28  GLU GLU C . n 
C 1 33  VAL 33  29  29  VAL VAL C . n 
C 1 34  VAL 34  30  30  VAL VAL C . n 
C 1 35  ALA 35  31  31  ALA ALA C . n 
C 1 36  LEU 36  32  32  LEU LEU C . n 
C 1 37  LYS 37  33  33  LYS LYS C . n 
C 1 38  LYS 38  34  34  LYS LYS C . n 
C 1 39  ILE 39  35  35  ILE ILE C . n 
C 1 40  ARG 40  36  36  ARG ARG C . n 
C 1 41  LEU 41  37  37  LEU LEU C . n 
C 1 42  ASP 42  38  38  ASP ASP C . n 
C 1 43  THR 43  39  39  THR THR C . n 
C 1 44  GLU 44  40  40  GLU GLU C . n 
C 1 45  THR 45  41  41  THR THR C . n 
C 1 46  GLU 46  42  42  GLU GLU C . n 
C 1 47  GLY 47  43  43  GLY GLY C . n 
C 1 48  VAL 48  44  44  VAL VAL C . n 
C 1 49  PRO 49  45  45  PRO PRO C . n 
C 1 50  SER 50  46  46  SER SER C . n 
C 1 51  THR 51  47  47  THR THR C . n 
C 1 52  ALA 52  48  48  ALA ALA C . n 
C 1 53  ILE 53  49  49  ILE ILE C . n 
C 1 54  ARG 54  50  50  ARG ARG C . n 
C 1 55  GLU 55  51  51  GLU GLU C . n 
C 1 56  ILE 56  52  52  ILE ILE C . n 
C 1 57  SER 57  53  53  SER SER C . n 
C 1 58  LEU 58  54  54  LEU LEU C . n 
C 1 59  LEU 59  55  55  LEU LEU C . n 
C 1 60  LYS 60  56  56  LYS LYS C . n 
C 1 61  GLU 61  57  57  GLU GLU C . n 
C 1 62  LEU 62  58  58  LEU LEU C . n 
C 1 63  ASN 63  59  59  ASN ASN C . n 
C 1 64  HIS 64  60  60  HIS HIS C . n 
C 1 65  PRO 65  61  61  PRO PRO C . n 
C 1 66  ASN 66  62  62  ASN ASN C . n 
C 1 67  ILE 67  63  63  ILE ILE C . n 
C 1 68  VAL 68  64  64  VAL VAL C . n 
C 1 69  LYS 69  65  65  LYS LYS C . n 
C 1 70  LEU 70  66  66  LEU LEU C . n 
C 1 71  LEU 71  67  67  LEU LEU C . n 
C 1 72  ASP 72  68  68  ASP ASP C . n 
C 1 73  VAL 73  69  69  VAL VAL C . n 
C 1 74  ILE 74  70  70  ILE ILE C . n 
C 1 75  HIS 75  71  71  HIS HIS C . n 
C 1 76  THR 76  72  72  THR THR C . n 
C 1 77  GLU 77  73  73  GLU GLU C . n 
C 1 78  ASN 78  74  74  ASN ASN C . n 
C 1 79  LYS 79  75  75  LYS LYS C . n 
C 1 80  LEU 80  76  76  LEU LEU C . n 
C 1 81  TYR 81  77  77  TYR TYR C . n 
C 1 82  LEU 82  78  78  LEU LEU C . n 
C 1 83  VAL 83  79  79  VAL VAL C . n 
C 1 84  PHE 84  80  80  PHE PHE C . n 
C 1 85  GLU 85  81  81  GLU GLU C . n 
C 1 86  PHE 86  82  82  PHE PHE C . n 
C 1 87  LEU 87  83  83  LEU LEU C . n 
C 1 88  HIS 88  84  84  HIS HIS C . n 
C 1 89  GLN 89  85  85  GLN GLN C . n 
C 1 90  ASP 90  86  86  ASP ASP C . n 
C 1 91  LEU 91  87  87  LEU LEU C . n 
C 1 92  LYS 92  88  88  LYS LYS C . n 
C 1 93  LYS 93  89  89  LYS LYS C . n 
C 1 94  PHE 94  90  90  PHE PHE C . n 
C 1 95  MET 95  91  91  MET MET C . n 
C 1 96  ASP 96  92  92  ASP ASP C . n 
C 1 97  ALA 97  93  93  ALA ALA C . n 
C 1 98  SER 98  94  94  SER SER C . n 
C 1 99  ALA 99  95  95  ALA ALA C . n 
C 1 100 LEU 100 96  96  LEU LEU C . n 
C 1 101 THR 101 97  97  THR THR C . n 
C 1 102 GLY 102 98  98  GLY GLY C . n 
C 1 103 ILE 103 99  99  ILE ILE C . n 
C 1 104 PRO 104 100 100 PRO PRO C . n 
C 1 105 LEU 105 101 101 LEU LEU C . n 
C 1 106 PRO 106 102 102 PRO PRO C . n 
C 1 107 LEU 107 103 103 LEU LEU C . n 
C 1 108 ILE 108 104 104 ILE ILE C . n 
C 1 109 LYS 109 105 105 LYS LYS C . n 
C 1 110 SER 110 106 106 SER SER C . n 
C 1 111 TYR 111 107 107 TYR TYR C . n 
C 1 112 LEU 112 108 108 LEU LEU C . n 
C 1 113 PHE 113 109 109 PHE PHE C . n 
C 1 114 GLN 114 110 110 GLN GLN C . n 
C 1 115 LEU 115 111 111 LEU LEU C . n 
C 1 116 LEU 116 112 112 LEU LEU C . n 
C 1 117 GLN 117 113 113 GLN GLN C . n 
C 1 118 GLY 118 114 114 GLY GLY C . n 
C 1 119 LEU 119 115 115 LEU LEU C . n 
C 1 120 ALA 120 116 116 ALA ALA C . n 
C 1 121 PHE 121 117 117 PHE PHE C . n 
C 1 122 CYS 122 118 118 CYS CYS C . n 
C 1 123 HIS 123 119 119 HIS HIS C . n 
C 1 124 SER 124 120 120 SER SER C . n 
C 1 125 HIS 125 121 121 HIS HIS C . n 
C 1 126 ARG 126 122 122 ARG ARG C . n 
C 1 127 VAL 127 123 123 VAL VAL C . n 
C 1 128 LEU 128 124 124 LEU LEU C . n 
C 1 129 HIS 129 125 125 HIS HIS C . n 
C 1 130 ARG 130 126 126 ARG ARG C . n 
C 1 131 ASP 131 127 127 ASP ASP C . n 
C 1 132 LEU 132 128 128 LEU LEU C . n 
C 1 133 LYS 133 129 129 LYS LYS C . n 
C 1 134 PRO 134 130 130 PRO PRO C . n 
C 1 135 GLN 135 131 131 GLN GLN C . n 
C 1 136 ASN 136 132 132 ASN ASN C . n 
C 1 137 LEU 137 133 133 LEU LEU C . n 
C 1 138 LEU 138 134 134 LEU LEU C . n 
C 1 139 ILE 139 135 135 ILE ILE C . n 
C 1 140 ASN 140 136 136 ASN ASN C . n 
C 1 141 THR 141 137 137 THR THR C . n 
C 1 142 GLU 142 138 138 GLU GLU C . n 
C 1 143 GLY 143 139 139 GLY GLY C . n 
C 1 144 ALA 144 140 140 ALA ALA C . n 
C 1 145 ILE 145 141 141 ILE ILE C . n 
C 1 146 LYS 146 142 142 LYS LYS C . n 
C 1 147 LEU 147 143 143 LEU LEU C . n 
C 1 148 ALA 148 144 144 ALA ALA C . n 
C 1 149 ASP 149 145 145 ASP ASP C . n 
C 1 150 PHE 150 146 146 PHE PHE C . n 
C 1 151 GLY 151 147 147 GLY GLY C . n 
C 1 152 LEU 152 148 148 LEU LEU C . n 
C 1 153 ALA 153 149 149 ALA ALA C . n 
C 1 154 ARG 154 150 150 ARG ARG C . n 
C 1 155 ALA 155 151 151 ALA ALA C . n 
C 1 156 PHE 156 152 152 PHE PHE C . n 
C 1 157 GLY 157 153 153 GLY GLY C . n 
C 1 158 VAL 158 154 154 VAL VAL C . n 
C 1 159 PRO 159 155 155 PRO PRO C . n 
C 1 160 VAL 160 156 156 VAL VAL C . n 
C 1 161 ARG 161 157 157 ARG ARG C . n 
C 1 162 THR 162 158 158 THR THR C . n 
C 1 163 TYR 163 159 159 TYR TYR C . n 
C 1 164 TPO 164 160 160 TPO TPO C . n 
C 1 165 HIS 165 161 161 HIS HIS C . n 
C 1 166 GLU 166 162 162 GLU GLU C . n 
C 1 167 VAL 167 163 163 VAL VAL C . n 
C 1 168 VAL 168 164 164 VAL VAL C . n 
C 1 169 THR 169 165 165 THR THR C . n 
C 1 170 LEU 170 166 166 LEU LEU C . n 
C 1 171 TRP 171 167 167 TRP TRP C . n 
C 1 172 TYR 172 168 168 TYR TYR C . n 
C 1 173 ARG 173 169 169 ARG ARG C . n 
C 1 174 ALA 174 170 170 ALA ALA C . n 
C 1 175 PRO 175 171 171 PRO PRO C . n 
C 1 176 GLU 176 172 172 GLU GLU C . n 
C 1 177 ILE 177 173 173 ILE ILE C . n 
C 1 178 LEU 178 174 174 LEU LEU C . n 
C 1 179 LEU 179 175 175 LEU LEU C . n 
C 1 180 GLY 180 176 176 GLY GLY C . n 
C 1 181 CYS 181 177 177 CYS CYS C . n 
C 1 182 LYS 182 178 178 LYS LYS C . n 
C 1 183 TYR 183 179 179 TYR TYR C . n 
C 1 184 TYR 184 180 180 TYR TYR C . n 
C 1 185 SER 185 181 181 SER SER C . n 
C 1 186 THR 186 182 182 THR THR C . n 
C 1 187 ALA 187 183 183 ALA ALA C . n 
C 1 188 VAL 188 184 184 VAL VAL C . n 
C 1 189 ASP 189 185 185 ASP ASP C . n 
C 1 190 ILE 190 186 186 ILE ILE C . n 
C 1 191 TRP 191 187 187 TRP TRP C . n 
C 1 192 SER 192 188 188 SER SER C . n 
C 1 193 LEU 193 189 189 LEU LEU C . n 
C 1 194 GLY 194 190 190 GLY GLY C . n 
C 1 195 CYS 195 191 191 CYS CYS C . n 
C 1 196 ILE 196 192 192 ILE ILE C . n 
C 1 197 PHE 197 193 193 PHE PHE C . n 
C 1 198 ALA 198 194 194 ALA ALA C . n 
C 1 199 GLU 199 195 195 GLU GLU C . n 
C 1 200 MET 200 196 196 MET MET C . n 
C 1 201 VAL 201 197 197 VAL VAL C . n 
C 1 202 THR 202 198 198 THR THR C . n 
C 1 203 ARG 203 199 199 ARG ARG C . n 
C 1 204 ARG 204 200 200 ARG ARG C . n 
C 1 205 ALA 205 201 201 ALA ALA C . n 
C 1 206 LEU 206 202 202 LEU LEU C . n 
C 1 207 PHE 207 203 203 PHE PHE C . n 
C 1 208 PRO 208 204 204 PRO PRO C . n 
C 1 209 GLY 209 205 205 GLY GLY C . n 
C 1 210 ASP 210 206 206 ASP ASP C . n 
C 1 211 SER 211 207 207 SER SER C . n 
C 1 212 GLU 212 208 208 GLU GLU C . n 
C 1 213 ILE 213 209 209 ILE ILE C . n 
C 1 214 ASP 214 210 210 ASP ASP C . n 
C 1 215 GLN 215 211 211 GLN GLN C . n 
C 1 216 LEU 216 212 212 LEU LEU C . n 
C 1 217 PHE 217 213 213 PHE PHE C . n 
C 1 218 ARG 218 214 214 ARG ARG C . n 
C 1 219 ILE 219 215 215 ILE ILE C . n 
C 1 220 PHE 220 216 216 PHE PHE C . n 
C 1 221 ARG 221 217 217 ARG ARG C . n 
C 1 222 THR 222 218 218 THR THR C . n 
C 1 223 LEU 223 219 219 LEU LEU C . n 
C 1 224 GLY 224 220 220 GLY GLY C . n 
C 1 225 THR 225 221 221 THR THR C . n 
C 1 226 PRO 226 222 ?   ?   ?   C . n 
C 1 227 ASP 227 223 ?   ?   ?   C . n 
C 1 228 GLU 228 224 ?   ?   ?   C . n 
C 1 229 VAL 229 225 ?   ?   ?   C . n 
C 1 230 VAL 230 226 226 VAL VAL C . n 
C 1 231 TRP 231 227 227 TRP TRP C . n 
C 1 232 PRO 232 228 228 PRO PRO C . n 
C 1 233 GLY 233 229 229 GLY GLY C . n 
C 1 234 VAL 234 230 230 VAL VAL C . n 
C 1 235 THR 235 231 231 THR THR C . n 
C 1 236 SER 236 232 232 SER SER C . n 
C 1 237 MET 237 233 233 MET MET C . n 
C 1 238 PRO 238 234 234 PRO PRO C . n 
C 1 239 ASP 239 235 235 ASP ASP C . n 
C 1 240 TYR 240 236 236 TYR TYR C . n 
C 1 241 LYS 241 237 237 LYS LYS C . n 
C 1 242 PRO 242 238 238 PRO PRO C . n 
C 1 243 SER 243 239 239 SER SER C . n 
C 1 244 PHE 244 240 ?   ?   ?   C . n 
C 1 245 PRO 245 241 ?   ?   ?   C . n 
C 1 246 LYS 246 242 ?   ?   ?   C . n 
C 1 247 TRP 247 243 ?   ?   ?   C . n 
C 1 248 ALA 248 244 ?   ?   ?   C . n 
C 1 249 ARG 249 245 ?   ?   ?   C . n 
C 1 250 GLN 250 246 ?   ?   ?   C . n 
C 1 251 ASP 251 247 ?   ?   ?   C . n 
C 1 252 PHE 252 248 ?   ?   ?   C . n 
C 1 253 SER 253 249 ?   ?   ?   C . n 
C 1 254 LYS 254 250 ?   ?   ?   C . n 
C 1 255 VAL 255 251 ?   ?   ?   C . n 
C 1 256 VAL 256 252 ?   ?   ?   C . n 
C 1 257 PRO 257 253 253 PRO PRO C . n 
C 1 258 PRO 258 254 254 PRO PRO C . n 
C 1 259 LEU 259 255 255 LEU LEU C . n 
C 1 260 ASP 260 256 256 ASP ASP C . n 
C 1 261 GLU 261 257 257 GLU GLU C . n 
C 1 262 ASP 262 258 258 ASP ASP C . n 
C 1 263 GLY 263 259 259 GLY GLY C . n 
C 1 264 ARG 264 260 260 ARG ARG C . n 
C 1 265 SER 265 261 261 SER SER C . n 
C 1 266 LEU 266 262 262 LEU LEU C . n 
C 1 267 LEU 267 263 263 LEU LEU C . n 
C 1 268 SER 268 264 264 SER SER C . n 
C 1 269 GLN 269 265 265 GLN GLN C . n 
C 1 270 MET 270 266 266 MET MET C . n 
C 1 271 LEU 271 267 267 LEU LEU C . n 
C 1 272 HIS 272 268 268 HIS HIS C . n 
C 1 273 TYR 273 269 269 TYR TYR C . n 
C 1 274 ASP 274 270 270 ASP ASP C . n 
C 1 275 PRO 275 271 271 PRO PRO C . n 
C 1 276 ASN 276 272 272 ASN ASN C . n 
C 1 277 LYS 277 273 273 LYS LYS C . n 
C 1 278 ARG 278 274 274 ARG ARG C . n 
C 1 279 ILE 279 275 275 ILE ILE C . n 
C 1 280 SER 280 276 276 SER SER C . n 
C 1 281 ALA 281 277 277 ALA ALA C . n 
C 1 282 LYS 282 278 278 LYS LYS C . n 
C 1 283 ALA 283 279 279 ALA ALA C . n 
C 1 284 ALA 284 280 280 ALA ALA C . n 
C 1 285 LEU 285 281 281 LEU LEU C . n 
C 1 286 ALA 286 282 282 ALA ALA C . n 
C 1 287 HIS 287 283 283 HIS HIS C . n 
C 1 288 PRO 288 284 284 PRO PRO C . n 
C 1 289 PHE 289 285 285 PHE PHE C . n 
C 1 290 PHE 290 286 286 PHE PHE C . n 
C 1 291 GLN 291 287 287 GLN GLN C . n 
C 1 292 ASP 292 288 288 ASP ASP C . n 
C 1 293 VAL 293 289 289 VAL VAL C . n 
C 1 294 THR 294 290 290 THR THR C . n 
C 1 295 LYS 295 291 291 LYS LYS C . n 
C 1 296 PRO 296 292 292 PRO PRO C . n 
C 1 297 VAL 297 293 293 VAL VAL C . n 
C 1 298 PRO 298 294 294 PRO PRO C . n 
C 1 299 HIS 299 295 295 HIS HIS C . n 
C 1 300 LEU 300 296 296 LEU LEU C . n 
C 1 301 ARG 301 297 ?   ?   ?   C . n 
C 1 302 LEU 302 298 ?   ?   ?   C . n 
D 2 1   GLY 1   171 171 GLY GLY D . n 
D 2 2   VAL 2   172 172 VAL VAL D . n 
D 2 3   ASN 3   173 173 ASN ASN D . n 
D 2 4   GLU 4   174 174 GLU GLU D . n 
D 2 5   VAL 5   175 175 VAL VAL D . n 
D 2 6   PRO 6   176 176 PRO PRO D . n 
D 2 7   ASP 7   177 177 ASP ASP D . n 
D 2 8   TYR 8   178 178 TYR TYR D . n 
D 2 9   HIS 9   179 179 HIS HIS D . n 
D 2 10  GLU 10  180 180 GLU GLU D . n 
D 2 11  ASP 11  181 181 ASP ASP D . n 
D 2 12  ILE 12  182 182 ILE ILE D . n 
D 2 13  HIS 13  183 183 HIS HIS D . n 
D 2 14  THR 14  184 184 THR THR D . n 
D 2 15  TYR 15  185 185 TYR TYR D . n 
D 2 16  LEU 16  186 186 LEU LEU D . n 
D 2 17  ARG 17  187 187 ARG ARG D . n 
D 2 18  GLU 18  188 188 GLU GLU D . n 
D 2 19  MET 19  189 189 MET MET D . n 
D 2 20  GLU 20  190 190 GLU GLU D . n 
D 2 21  VAL 21  191 191 VAL VAL D . n 
D 2 22  LYS 22  192 192 LYS LYS D . n 
D 2 23  CYS 23  193 193 CYS CYS D . n 
D 2 24  LYS 24  194 194 LYS LYS D . n 
D 2 25  PRO 25  195 195 PRO PRO D . n 
D 2 26  LYS 26  196 196 LYS LYS D . n 
D 2 27  VAL 27  197 197 VAL VAL D . n 
D 2 28  GLY 28  198 198 GLY GLY D . n 
D 2 29  TYR 29  199 199 TYR TYR D . n 
D 2 30  MET 30  200 200 MET MET D . n 
D 2 31  LYS 31  201 201 LYS LYS D . n 
D 2 32  LYS 32  202 202 LYS LYS D . n 
D 2 33  GLN 33  203 203 GLN GLN D . n 
D 2 34  PRO 34  204 204 PRO PRO D . n 
D 2 35  ASP 35  205 205 ASP ASP D . n 
D 2 36  ILE 36  206 206 ILE ILE D . n 
D 2 37  THR 37  207 207 THR THR D . n 
D 2 38  ASN 38  208 208 ASN ASN D . n 
D 2 39  SER 39  209 209 SER SER D . n 
D 2 40  MET 40  210 210 MET MET D . n 
D 2 41  ARG 41  211 211 ARG ARG D . n 
D 2 42  ALA 42  212 212 ALA ALA D . n 
D 2 43  ILE 43  213 213 ILE ILE D . n 
D 2 44  LEU 44  214 214 LEU LEU D . n 
D 2 45  VAL 45  215 215 VAL VAL D . n 
D 2 46  ASP 46  216 216 ASP ASP D . n 
D 2 47  TRP 47  217 217 TRP TRP D . n 
D 2 48  LEU 48  218 218 LEU LEU D . n 
D 2 49  VAL 49  219 219 VAL VAL D . n 
D 2 50  GLU 50  220 220 GLU GLU D . n 
D 2 51  VAL 51  221 221 VAL VAL D . n 
D 2 52  GLY 52  222 222 GLY GLY D . n 
D 2 53  GLU 53  223 223 GLU GLU D . n 
D 2 54  GLU 54  224 224 GLU GLU D . n 
D 2 55  TYR 55  225 225 TYR TYR D . n 
D 2 56  LYS 56  226 226 LYS LYS D . n 
D 2 57  LEU 57  227 227 LEU LEU D . n 
D 2 58  GLN 58  228 228 GLN GLN D . n 
D 2 59  ASN 59  229 229 ASN ASN D . n 
D 2 60  GLU 60  230 230 GLU GLU D . n 
D 2 61  THR 61  231 231 THR THR D . n 
D 2 62  LEU 62  232 232 LEU LEU D . n 
D 2 63  HIS 63  233 233 HIS HIS D . n 
D 2 64  LEU 64  234 234 LEU LEU D . n 
D 2 65  ALA 65  235 235 ALA ALA D . n 
D 2 66  VAL 66  236 236 VAL VAL D . n 
D 2 67  ASN 67  237 237 ASN ASN D . n 
D 2 68  TYR 68  238 238 TYR TYR D . n 
D 2 69  ILE 69  239 239 ILE ILE D . n 
D 2 70  ASP 70  240 240 ASP ASP D . n 
D 2 71  ARG 71  241 241 ARG ARG D . n 
D 2 72  PHE 72  242 242 PHE PHE D . n 
D 2 73  LEU 73  243 243 LEU LEU D . n 
D 2 74  SER 74  244 244 SER SER D . n 
D 2 75  SER 75  245 245 SER SER D . n 
D 2 76  MET 76  246 246 MET MET D . n 
D 2 77  SER 77  247 247 SER SER D . n 
D 2 78  VAL 78  248 248 VAL VAL D . n 
D 2 79  LEU 79  249 249 LEU LEU D . n 
D 2 80  ARG 80  250 250 ARG ARG D . n 
D 2 81  GLY 81  251 251 GLY GLY D . n 
D 2 82  LYS 82  252 252 LYS LYS D . n 
D 2 83  LEU 83  253 253 LEU LEU D . n 
D 2 84  GLN 84  254 254 GLN GLN D . n 
D 2 85  LEU 85  255 255 LEU LEU D . n 
D 2 86  VAL 86  256 256 VAL VAL D . n 
D 2 87  GLY 87  257 257 GLY GLY D . n 
D 2 88  THR 88  258 258 THR THR D . n 
D 2 89  ALA 89  259 259 ALA ALA D . n 
D 2 90  ALA 90  260 260 ALA ALA D . n 
D 2 91  MET 91  261 261 MET MET D . n 
D 2 92  LEU 92  262 262 LEU LEU D . n 
D 2 93  LEU 93  263 263 LEU LEU D . n 
D 2 94  ALA 94  264 264 ALA ALA D . n 
D 2 95  SER 95  265 265 SER SER D . n 
D 2 96  LYS 96  266 266 LYS LYS D . n 
D 2 97  PHE 97  267 267 PHE PHE D . n 
D 2 98  GLU 98  268 268 GLU GLU D . n 
D 2 99  GLU 99  269 269 GLU GLU D . n 
D 2 100 ILE 100 270 270 ILE ILE D . n 
D 2 101 TYR 101 271 271 TYR TYR D . n 
D 2 102 PRO 102 272 272 PRO PRO D . n 
D 2 103 PRO 103 273 273 PRO PRO D . n 
D 2 104 GLU 104 274 274 GLU GLU D . n 
D 2 105 VAL 105 275 275 VAL VAL D . n 
D 2 106 ALA 106 276 276 ALA ALA D . n 
D 2 107 GLU 107 277 277 GLU GLU D . n 
D 2 108 PHE 108 278 278 PHE PHE D . n 
D 2 109 VAL 109 279 279 VAL VAL D . n 
D 2 110 TYR 110 280 280 TYR TYR D . n 
D 2 111 ILE 111 281 281 ILE ILE D . n 
D 2 112 THR 112 282 282 THR THR D . n 
D 2 113 ASP 113 283 283 ASP ASP D . n 
D 2 114 ASP 114 284 284 ASP ASP D . n 
D 2 115 THR 115 285 285 THR THR D . n 
D 2 116 TYR 116 286 286 TYR TYR D . n 
D 2 117 THR 117 287 287 THR THR D . n 
D 2 118 LYS 118 288 288 LYS LYS D . n 
D 2 119 LYS 119 289 289 LYS LYS D . n 
D 2 120 GLN 120 290 290 GLN GLN D . n 
D 2 121 VAL 121 291 291 VAL VAL D . n 
D 2 122 LEU 122 292 292 LEU LEU D . n 
D 2 123 ARG 123 293 293 ARG ARG D . n 
D 2 124 MET 124 294 294 MET MET D . n 
D 2 125 GLU 125 295 295 GLU GLU D . n 
D 2 126 HIS 126 296 296 HIS HIS D . n 
D 2 127 LEU 127 297 297 LEU LEU D . n 
D 2 128 VAL 128 298 298 VAL VAL D . n 
D 2 129 LEU 129 299 299 LEU LEU D . n 
D 2 130 LYS 130 300 300 LYS LYS D . n 
D 2 131 VAL 131 301 301 VAL VAL D . n 
D 2 132 LEU 132 302 302 LEU LEU D . n 
D 2 133 ALA 133 303 303 ALA ALA D . n 
D 2 134 PHE 134 304 304 PHE PHE D . n 
D 2 135 ASP 135 305 305 ASP ASP D . n 
D 2 136 LEU 136 306 306 LEU LEU D . n 
D 2 137 ALA 137 307 307 ALA ALA D . n 
D 2 138 ALA 138 308 308 ALA ALA D . n 
D 2 139 PRO 139 309 309 PRO PRO D . n 
D 2 140 THR 140 310 310 THR THR D . n 
D 2 141 ILE 141 311 311 ILE ILE D . n 
D 2 142 ASN 142 312 312 ASN ASN D . n 
D 2 143 GLN 143 313 313 GLN GLN D . n 
D 2 144 PHE 144 314 314 PHE PHE D . n 
D 2 145 LEU 145 315 315 LEU LEU D . n 
D 2 146 THR 146 316 316 THR THR D . n 
D 2 147 GLN 147 317 317 GLN GLN D . n 
D 2 148 TYR 148 318 318 TYR TYR D . n 
D 2 149 PHE 149 319 319 PHE PHE D . n 
D 2 150 LEU 150 320 320 LEU LEU D . n 
D 2 151 HIS 151 321 321 HIS HIS D . n 
D 2 152 GLN 152 322 322 GLN GLN D . n 
D 2 153 GLN 153 323 323 GLN GLN D . n 
D 2 154 PRO 154 324 324 PRO PRO D . n 
D 2 155 ALA 155 325 325 ALA ALA D . n 
D 2 156 ASN 156 326 326 ASN ASN D . n 
D 2 157 CYS 157 327 327 CYS CYS D . n 
D 2 158 LYS 158 328 328 LYS LYS D . n 
D 2 159 VAL 159 329 329 VAL VAL D . n 
D 2 160 GLU 160 330 330 GLU GLU D . n 
D 2 161 SER 161 331 331 SER SER D . n 
D 2 162 LEU 162 332 332 LEU LEU D . n 
D 2 163 ALA 163 333 333 ALA ALA D . n 
D 2 164 MET 164 334 334 MET MET D . n 
D 2 165 PHE 165 335 335 PHE PHE D . n 
D 2 166 LEU 166 336 336 LEU LEU D . n 
D 2 167 GLY 167 337 337 GLY GLY D . n 
D 2 168 GLU 168 338 338 GLU GLU D . n 
D 2 169 LEU 169 339 339 LEU LEU D . n 
D 2 170 SER 170 340 340 SER SER D . n 
D 2 171 LEU 171 341 341 LEU LEU D . n 
D 2 172 ILE 172 342 342 ILE ILE D . n 
D 2 173 ASP 173 343 343 ASP ASP D . n 
D 2 174 ALA 174 344 344 ALA ALA D . n 
D 2 175 ASP 175 345 345 ASP ASP D . n 
D 2 176 PRO 176 346 346 PRO PRO D . n 
D 2 177 TYR 177 347 347 TYR TYR D . n 
D 2 178 LEU 178 348 348 LEU LEU D . n 
D 2 179 LYS 179 349 349 LYS LYS D . n 
D 2 180 TYR 180 350 350 TYR TYR D . n 
D 2 181 LEU 181 351 351 LEU LEU D . n 
D 2 182 PRO 182 352 352 PRO PRO D . n 
D 2 183 SER 183 353 353 SER SER D . n 
D 2 184 VAL 184 354 354 VAL VAL D . n 
D 2 185 ILE 185 355 355 ILE ILE D . n 
D 2 186 ALA 186 356 356 ALA ALA D . n 
D 2 187 ALA 187 357 357 ALA ALA D . n 
D 2 188 ALA 188 358 358 ALA ALA D . n 
D 2 189 ALA 189 359 359 ALA ALA D . n 
D 2 190 PHE 190 360 360 PHE PHE D . n 
D 2 191 HIS 191 361 361 HIS HIS D . n 
D 2 192 LEU 192 362 362 LEU LEU D . n 
D 2 193 ALA 193 363 363 ALA ALA D . n 
D 2 194 LEU 194 364 364 LEU LEU D . n 
D 2 195 TYR 195 365 365 TYR TYR D . n 
D 2 196 THR 196 366 366 THR THR D . n 
D 2 197 VAL 197 367 367 VAL VAL D . n 
D 2 198 THR 198 368 368 THR THR D . n 
D 2 199 GLY 199 369 369 GLY GLY D . n 
D 2 200 GLN 200 370 370 GLN GLN D . n 
D 2 201 SER 201 371 371 SER SER D . n 
D 2 202 TRP 202 372 372 TRP TRP D . n 
D 2 203 PRO 203 373 373 PRO PRO D . n 
D 2 204 GLU 204 374 374 GLU GLU D . n 
D 2 205 SER 205 375 375 SER SER D . n 
D 2 206 LEU 206 376 376 LEU LEU D . n 
D 2 207 VAL 207 377 377 VAL VAL D . n 
D 2 208 GLN 208 378 378 GLN GLN D . n 
D 2 209 LYS 209 379 379 LYS LYS D . n 
D 2 210 THR 210 380 380 THR THR D . n 
D 2 211 GLY 211 381 381 GLY GLY D . n 
D 2 212 TYR 212 382 382 TYR TYR D . n 
D 2 213 THR 213 383 383 THR THR D . n 
D 2 214 LEU 214 384 384 LEU LEU D . n 
D 2 215 GLU 215 385 385 GLU GLU D . n 
D 2 216 THR 216 386 386 THR THR D . n 
D 2 217 LEU 217 387 387 LEU LEU D . n 
D 2 218 LYS 218 388 388 LYS LYS D . n 
D 2 219 PRO 219 389 389 PRO PRO D . n 
D 2 220 CYS 220 390 390 CYS CYS D . n 
D 2 221 LEU 221 391 391 LEU LEU D . n 
D 2 222 LEU 222 392 392 LEU LEU D . n 
D 2 223 ASP 223 393 393 ASP ASP D . n 
D 2 224 LEU 224 394 394 LEU LEU D . n 
D 2 225 HIS 225 395 395 HIS HIS D . n 
D 2 226 GLN 226 396 396 GLN GLN D . n 
D 2 227 THR 227 397 397 THR THR D . n 
D 2 228 TYR 228 398 398 TYR TYR D . n 
D 2 229 LEU 229 399 399 LEU LEU D . n 
D 2 230 ARG 230 400 400 ARG ARG D . n 
D 2 231 ALA 231 401 401 ALA ALA D . n 
D 2 232 PRO 232 402 402 PRO PRO D . n 
D 2 233 GLN 233 403 403 GLN GLN D . n 
D 2 234 HIS 234 404 404 HIS HIS D . n 
D 2 235 ALA 235 405 405 ALA ALA D . n 
D 2 236 GLN 236 406 406 GLN GLN D . n 
D 2 237 GLN 237 407 407 GLN GLN D . n 
D 2 238 SER 238 408 408 SER SER D . n 
D 2 239 ILE 239 409 409 ILE ILE D . n 
D 2 240 ARG 240 410 410 ARG ARG D . n 
D 2 241 GLU 241 411 411 GLU GLU D . n 
D 2 242 LYS 242 412 412 LYS LYS D . n 
D 2 243 TYR 243 413 413 TYR TYR D . n 
D 2 244 LYS 244 414 414 LYS LYS D . n 
D 2 245 ASN 245 415 415 ASN ASN D . n 
D 2 246 SER 246 416 416 SER SER D . n 
D 2 247 LYS 247 417 417 LYS LYS D . n 
D 2 248 TYR 248 418 418 TYR TYR D . n 
D 2 249 HIS 249 419 419 HIS HIS D . n 
D 2 250 GLY 250 420 420 GLY GLY D . n 
D 2 251 VAL 251 421 421 VAL VAL D . n 
D 2 252 SER 252 422 422 SER SER D . n 
D 2 253 LEU 253 423 423 LEU LEU D . n 
D 2 254 LEU 254 424 424 LEU LEU D . n 
D 2 255 ASN 255 425 425 ASN ASN D . n 
D 2 256 PRO 256 426 426 PRO PRO D . n 
D 2 257 PRO 257 427 427 PRO PRO D . n 
D 2 258 GLU 258 428 428 GLU GLU D . n 
D 2 259 THR 259 429 429 THR THR D . n 
D 2 260 LEU 260 430 430 LEU LEU D . n 
D 2 261 ASN 261 431 431 ASN ASN D . n 
D 2 262 VAL 262 432 ?   ?   ?   D . n 
D 2 263 HIS 263 433 ?   ?   ?   D . n 
D 2 264 HIS 264 434 ?   ?   ?   D . n 
D 2 265 HIS 265 435 ?   ?   ?   D . n 
D 2 266 HIS 266 436 ?   ?   ?   D . n 
D 2 267 HIS 267 437 ?   ?   ?   D . n 
D 2 268 HIS 268 438 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        BYZ 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   BYZ 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 BYZ 1   601 601  BYZ DRG A . 
F 3 BYZ 1   603 1608 BYZ DRG A . 
G 3 BYZ 1   604 1610 BYZ DRG A . 
H 3 BYZ 1   605 1611 BYZ DRG A . 
I 3 BYZ 1   606 1612 BYZ DRG A . 
J 3 BYZ 1   607 1701 BYZ DRG A . 
K 3 BYZ 1   501 1604 BYZ DRG B . 
L 3 BYZ 1   502 1605 BYZ DRG B . 
M 3 BYZ 1   501 501  BYZ DRG C . 
N 3 BYZ 1   502 1606 BYZ DRG C . 
O 3 BYZ 1   503 1609 BYZ DRG C . 
P 3 BYZ 1   501 603  BYZ DRG D . 
Q 3 BYZ 1   502 1613 BYZ DRG D . 
R 4 HOH 1   701 408  HOH HOH A . 
R 4 HOH 2   702 428  HOH HOH A . 
R 4 HOH 3   703 95   HOH HOH A . 
R 4 HOH 4   704 50   HOH HOH A . 
R 4 HOH 5   705 404  HOH HOH A . 
R 4 HOH 6   706 183  HOH HOH A . 
R 4 HOH 7   707 170  HOH HOH A . 
R 4 HOH 8   708 453  HOH HOH A . 
R 4 HOH 9   709 472  HOH HOH A . 
R 4 HOH 10  710 436  HOH HOH A . 
R 4 HOH 11  711 80   HOH HOH A . 
R 4 HOH 12  712 94   HOH HOH A . 
R 4 HOH 13  713 525  HOH HOH A . 
R 4 HOH 14  714 425  HOH HOH A . 
R 4 HOH 15  715 51   HOH HOH A . 
R 4 HOH 16  716 417  HOH HOH A . 
R 4 HOH 17  717 440  HOH HOH A . 
R 4 HOH 18  718 52   HOH HOH A . 
R 4 HOH 19  719 423  HOH HOH A . 
R 4 HOH 20  720 422  HOH HOH A . 
R 4 HOH 21  721 8    HOH HOH A . 
R 4 HOH 22  722 175  HOH HOH A . 
R 4 HOH 23  723 15   HOH HOH A . 
R 4 HOH 24  724 444  HOH HOH A . 
R 4 HOH 25  725 463  HOH HOH A . 
R 4 HOH 26  726 407  HOH HOH A . 
R 4 HOH 27  727 462  HOH HOH A . 
R 4 HOH 28  728 101  HOH HOH A . 
R 4 HOH 29  729 478  HOH HOH A . 
R 4 HOH 30  730 515  HOH HOH A . 
R 4 HOH 31  731 22   HOH HOH A . 
R 4 HOH 32  732 594  HOH HOH A . 
R 4 HOH 33  733 510  HOH HOH A . 
R 4 HOH 34  734 134  HOH HOH A . 
R 4 HOH 35  735 525  HOH HOH A . 
R 4 HOH 36  736 479  HOH HOH A . 
R 4 HOH 37  737 520  HOH HOH A . 
R 4 HOH 38  738 474  HOH HOH A . 
R 4 HOH 39  739 434  HOH HOH A . 
R 4 HOH 40  740 470  HOH HOH A . 
R 4 HOH 41  741 414  HOH HOH A . 
R 4 HOH 42  742 469  HOH HOH A . 
R 4 HOH 43  743 457  HOH HOH A . 
R 4 HOH 44  744 84   HOH HOH A . 
R 4 HOH 45  745 459  HOH HOH A . 
R 4 HOH 46  746 464  HOH HOH A . 
R 4 HOH 47  747 442  HOH HOH A . 
R 4 HOH 48  748 545  HOH HOH A . 
R 4 HOH 49  749 100  HOH HOH A . 
R 4 HOH 50  750 120  HOH HOH A . 
R 4 HOH 51  751 504  HOH HOH A . 
R 4 HOH 52  752 140  HOH HOH A . 
R 4 HOH 53  753 121  HOH HOH A . 
R 4 HOH 54  754 424  HOH HOH A . 
R 4 HOH 55  755 490  HOH HOH A . 
R 4 HOH 56  756 477  HOH HOH A . 
R 4 HOH 57  757 465  HOH HOH A . 
R 4 HOH 58  758 482  HOH HOH A . 
R 4 HOH 59  759 448  HOH HOH A . 
R 4 HOH 60  760 438  HOH HOH A . 
R 4 HOH 61  761 427  HOH HOH A . 
R 4 HOH 62  762 461  HOH HOH A . 
R 4 HOH 63  763 491  HOH HOH A . 
R 4 HOH 64  764 131  HOH HOH A . 
R 4 HOH 65  765 468  HOH HOH A . 
R 4 HOH 66  766 38   HOH HOH A . 
R 4 HOH 67  767 511  HOH HOH A . 
R 4 HOH 68  768 429  HOH HOH A . 
R 4 HOH 69  769 13   HOH HOH A . 
R 4 HOH 70  770 522  HOH HOH A . 
R 4 HOH 71  771 509  HOH HOH A . 
R 4 HOH 72  772 403  HOH HOH A . 
R 4 HOH 73  773 451  HOH HOH A . 
R 4 HOH 74  774 560  HOH HOH A . 
R 4 HOH 75  775 503  HOH HOH A . 
R 4 HOH 76  776 27   HOH HOH A . 
R 4 HOH 77  777 99   HOH HOH A . 
R 4 HOH 78  778 506  HOH HOH A . 
R 4 HOH 79  779 4    HOH HOH A . 
R 4 HOH 80  780 419  HOH HOH A . 
R 4 HOH 81  781 200  HOH HOH A . 
R 4 HOH 82  782 577  HOH HOH A . 
R 4 HOH 83  783 204  HOH HOH A . 
R 4 HOH 84  784 485  HOH HOH A . 
R 4 HOH 85  785 171  HOH HOH A . 
R 4 HOH 86  786 114  HOH HOH A . 
R 4 HOH 87  787 517  HOH HOH A . 
R 4 HOH 88  788 532  HOH HOH A . 
R 4 HOH 89  789 481  HOH HOH A . 
R 4 HOH 90  790 458  HOH HOH A . 
R 4 HOH 91  791 447  HOH HOH A . 
R 4 HOH 92  792 19   HOH HOH A . 
R 4 HOH 93  793 563  HOH HOH A . 
R 4 HOH 94  794 96   HOH HOH A . 
R 4 HOH 95  795 553  HOH HOH A . 
R 4 HOH 96  796 146  HOH HOH A . 
R 4 HOH 97  797 45   HOH HOH A . 
R 4 HOH 98  798 536  HOH HOH A . 
R 4 HOH 99  799 514  HOH HOH A . 
R 4 HOH 100 800 118  HOH HOH A . 
R 4 HOH 101 801 44   HOH HOH A . 
R 4 HOH 102 802 484  HOH HOH A . 
R 4 HOH 103 803 527  HOH HOH A . 
R 4 HOH 104 804 502  HOH HOH A . 
R 4 HOH 105 805 89   HOH HOH A . 
R 4 HOH 106 806 2    HOH HOH A . 
R 4 HOH 107 807 544  HOH HOH A . 
R 4 HOH 108 808 188  HOH HOH A . 
R 4 HOH 109 809 23   HOH HOH A . 
R 4 HOH 110 810 524  HOH HOH A . 
R 4 HOH 111 811 119  HOH HOH A . 
R 4 HOH 112 812 466  HOH HOH A . 
R 4 HOH 113 813 535  HOH HOH A . 
R 4 HOH 114 814 541  HOH HOH A . 
R 4 HOH 115 815 181  HOH HOH A . 
R 4 HOH 116 816 7    HOH HOH A . 
R 4 HOH 117 817 501  HOH HOH A . 
R 4 HOH 118 818 40   HOH HOH A . 
R 4 HOH 119 819 102  HOH HOH A . 
R 4 HOH 120 820 571  HOH HOH A . 
R 4 HOH 121 821 556  HOH HOH A . 
R 4 HOH 122 822 487  HOH HOH A . 
R 4 HOH 123 823 573  HOH HOH A . 
R 4 HOH 124 824 124  HOH HOH A . 
R 4 HOH 125 825 526  HOH HOH A . 
R 4 HOH 126 826 53   HOH HOH A . 
R 4 HOH 127 827 104  HOH HOH A . 
R 4 HOH 128 828 551  HOH HOH A . 
R 4 HOH 129 829 569  HOH HOH A . 
R 4 HOH 130 830 552  HOH HOH A . 
R 4 HOH 131 831 59   HOH HOH A . 
R 4 HOH 132 832 583  HOH HOH A . 
R 4 HOH 133 833 217  HOH HOH A . 
R 4 HOH 134 834 198  HOH HOH A . 
R 4 HOH 135 835 587  HOH HOH A . 
R 4 HOH 136 836 455  HOH HOH A . 
R 4 HOH 137 837 49   HOH HOH A . 
R 4 HOH 138 838 57   HOH HOH A . 
R 4 HOH 139 839 582  HOH HOH A . 
R 4 HOH 140 840 46   HOH HOH A . 
R 4 HOH 141 841 590  HOH HOH A . 
R 4 HOH 142 842 557  HOH HOH A . 
R 4 HOH 143 843 162  HOH HOH A . 
S 4 HOH 1   601 148  HOH HOH B . 
S 4 HOH 2   602 508  HOH HOH B . 
S 4 HOH 3   603 534  HOH HOH B . 
S 4 HOH 4   604 510  HOH HOH B . 
S 4 HOH 5   605 524  HOH HOH B . 
S 4 HOH 6   606 547  HOH HOH B . 
S 4 HOH 7   607 77   HOH HOH B . 
S 4 HOH 8   608 26   HOH HOH B . 
S 4 HOH 9   609 189  HOH HOH B . 
S 4 HOH 10  610 133  HOH HOH B . 
S 4 HOH 11  611 143  HOH HOH B . 
S 4 HOH 12  612 25   HOH HOH B . 
S 4 HOH 13  613 88   HOH HOH B . 
S 4 HOH 14  614 74   HOH HOH B . 
S 4 HOH 15  615 71   HOH HOH B . 
S 4 HOH 16  616 576  HOH HOH B . 
S 4 HOH 17  617 78   HOH HOH B . 
S 4 HOH 18  618 532  HOH HOH B . 
S 4 HOH 19  619 48   HOH HOH B . 
S 4 HOH 20  620 60   HOH HOH B . 
S 4 HOH 21  621 41   HOH HOH B . 
S 4 HOH 22  622 37   HOH HOH B . 
S 4 HOH 23  623 570  HOH HOH B . 
S 4 HOH 24  624 537  HOH HOH B . 
S 4 HOH 25  625 70   HOH HOH B . 
S 4 HOH 26  626 504  HOH HOH B . 
S 4 HOH 27  627 598  HOH HOH B . 
S 4 HOH 28  628 634  HOH HOH B . 
S 4 HOH 29  629 109  HOH HOH B . 
S 4 HOH 30  630 605  HOH HOH B . 
S 4 HOH 31  631 558  HOH HOH B . 
S 4 HOH 32  632 501  HOH HOH B . 
S 4 HOH 33  633 592  HOH HOH B . 
S 4 HOH 34  634 531  HOH HOH B . 
S 4 HOH 35  635 589  HOH HOH B . 
S 4 HOH 36  636 584  HOH HOH B . 
S 4 HOH 37  637 624  HOH HOH B . 
S 4 HOH 38  638 593  HOH HOH B . 
S 4 HOH 39  639 511  HOH HOH B . 
S 4 HOH 40  640 543  HOH HOH B . 
S 4 HOH 41  641 126  HOH HOH B . 
S 4 HOH 42  642 520  HOH HOH B . 
S 4 HOH 43  643 456  HOH HOH B . 
S 4 HOH 44  644 568  HOH HOH B . 
S 4 HOH 45  645 567  HOH HOH B . 
S 4 HOH 46  646 601  HOH HOH B . 
S 4 HOH 47  647 552  HOH HOH B . 
S 4 HOH 48  648 609  HOH HOH B . 
S 4 HOH 49  649 591  HOH HOH B . 
S 4 HOH 50  650 599  HOH HOH B . 
S 4 HOH 51  651 617  HOH HOH B . 
S 4 HOH 52  652 615  HOH HOH B . 
S 4 HOH 53  653 512  HOH HOH B . 
S 4 HOH 54  654 579  HOH HOH B . 
S 4 HOH 55  655 642  HOH HOH B . 
S 4 HOH 56  656 633  HOH HOH B . 
S 4 HOH 57  657 98   HOH HOH B . 
S 4 HOH 58  658 600  HOH HOH B . 
S 4 HOH 59  659 35   HOH HOH B . 
S 4 HOH 60  660 529  HOH HOH B . 
S 4 HOH 61  661 215  HOH HOH B . 
S 4 HOH 62  662 571  HOH HOH B . 
S 4 HOH 63  663 36   HOH HOH B . 
S 4 HOH 64  664 196  HOH HOH B . 
S 4 HOH 65  665 560  HOH HOH B . 
S 4 HOH 66  666 185  HOH HOH B . 
S 4 HOH 67  667 622  HOH HOH B . 
S 4 HOH 68  668 636  HOH HOH B . 
S 4 HOH 69  669 621  HOH HOH B . 
S 4 HOH 70  670 630  HOH HOH B . 
S 4 HOH 71  671 82   HOH HOH B . 
S 4 HOH 72  672 638  HOH HOH B . 
S 4 HOH 73  673 594  HOH HOH B . 
S 4 HOH 74  674 607  HOH HOH B . 
S 4 HOH 75  675 24   HOH HOH B . 
S 4 HOH 76  676 12   HOH HOH B . 
S 4 HOH 77  677 550  HOH HOH B . 
S 4 HOH 78  678 637  HOH HOH B . 
S 4 HOH 79  679 643  HOH HOH B . 
S 4 HOH 80  680 608  HOH HOH B . 
S 4 HOH 81  681 201  HOH HOH B . 
S 4 HOH 82  682 613  HOH HOH B . 
S 4 HOH 83  683 219  HOH HOH B . 
S 4 HOH 84  684 566  HOH HOH B . 
S 4 HOH 85  685 582  HOH HOH B . 
S 4 HOH 86  686 627  HOH HOH B . 
S 4 HOH 87  687 618  HOH HOH B . 
S 4 HOH 88  688 214  HOH HOH B . 
S 4 HOH 89  689 178  HOH HOH B . 
S 4 HOH 90  690 182  HOH HOH B . 
S 4 HOH 91  691 640  HOH HOH B . 
S 4 HOH 92  692 544  HOH HOH B . 
S 4 HOH 93  693 631  HOH HOH B . 
S 4 HOH 94  694 629  HOH HOH B . 
S 4 HOH 95  695 612  HOH HOH B . 
S 4 HOH 96  696 93   HOH HOH B . 
S 4 HOH 97  697 620  HOH HOH B . 
S 4 HOH 98  698 116  HOH HOH B . 
S 4 HOH 99  699 583  HOH HOH B . 
S 4 HOH 100 700 650  HOH HOH B . 
S 4 HOH 101 701 635  HOH HOH B . 
S 4 HOH 102 702 641  HOH HOH B . 
S 4 HOH 103 703 664  HOH HOH B . 
S 4 HOH 104 704 221  HOH HOH B . 
S 4 HOH 105 705 668  HOH HOH B . 
S 4 HOH 106 706 669  HOH HOH B . 
S 4 HOH 107 707 623  HOH HOH B . 
S 4 HOH 108 708 127  HOH HOH B . 
S 4 HOH 109 709 653  HOH HOH B . 
S 4 HOH 110 710 42   HOH HOH B . 
S 4 HOH 111 711 5    HOH HOH B . 
S 4 HOH 112 712 678  HOH HOH B . 
S 4 HOH 113 713 225  HOH HOH B . 
S 4 HOH 114 714 676  HOH HOH B . 
S 4 HOH 115 715 680  HOH HOH B . 
S 4 HOH 116 716 186  HOH HOH B . 
S 4 HOH 117 717 62   HOH HOH B . 
T 4 HOH 1   601 67   HOH HOH C . 
T 4 HOH 2   602 107  HOH HOH C . 
T 4 HOH 3   603 407  HOH HOH C . 
T 4 HOH 4   604 187  HOH HOH C . 
T 4 HOH 5   605 173  HOH HOH C . 
T 4 HOH 6   606 424  HOH HOH C . 
T 4 HOH 7   607 406  HOH HOH C . 
T 4 HOH 8   608 422  HOH HOH C . 
T 4 HOH 9   609 69   HOH HOH C . 
T 4 HOH 10  610 411  HOH HOH C . 
T 4 HOH 11  611 21   HOH HOH C . 
T 4 HOH 12  612 431  HOH HOH C . 
T 4 HOH 13  613 6    HOH HOH C . 
T 4 HOH 14  614 430  HOH HOH C . 
T 4 HOH 15  615 164  HOH HOH C . 
T 4 HOH 16  616 28   HOH HOH C . 
T 4 HOH 17  617 32   HOH HOH C . 
T 4 HOH 18  618 144  HOH HOH C . 
T 4 HOH 19  619 167  HOH HOH C . 
T 4 HOH 20  620 410  HOH HOH C . 
T 4 HOH 21  621 401  HOH HOH C . 
T 4 HOH 22  622 428  HOH HOH C . 
T 4 HOH 23  623 423  HOH HOH C . 
T 4 HOH 24  624 17   HOH HOH C . 
T 4 HOH 25  625 440  HOH HOH C . 
T 4 HOH 26  626 115  HOH HOH C . 
T 4 HOH 27  627 437  HOH HOH C . 
T 4 HOH 28  628 9    HOH HOH C . 
T 4 HOH 29  629 420  HOH HOH C . 
T 4 HOH 30  630 192  HOH HOH C . 
T 4 HOH 31  631 427  HOH HOH C . 
T 4 HOH 32  632 106  HOH HOH C . 
T 4 HOH 33  633 465  HOH HOH C . 
T 4 HOH 34  634 504  HOH HOH C . 
T 4 HOH 35  635 10   HOH HOH C . 
T 4 HOH 36  636 3    HOH HOH C . 
T 4 HOH 37  637 416  HOH HOH C . 
T 4 HOH 38  638 432  HOH HOH C . 
T 4 HOH 39  639 113  HOH HOH C . 
T 4 HOH 40  640 55   HOH HOH C . 
T 4 HOH 41  641 91   HOH HOH C . 
T 4 HOH 42  642 426  HOH HOH C . 
T 4 HOH 43  643 64   HOH HOH C . 
T 4 HOH 44  644 451  HOH HOH C . 
T 4 HOH 45  645 58   HOH HOH C . 
T 4 HOH 46  646 439  HOH HOH C . 
T 4 HOH 47  647 83   HOH HOH C . 
T 4 HOH 48  648 54   HOH HOH C . 
T 4 HOH 49  649 156  HOH HOH C . 
T 4 HOH 50  650 412  HOH HOH C . 
T 4 HOH 51  651 191  HOH HOH C . 
T 4 HOH 52  652 142  HOH HOH C . 
T 4 HOH 53  653 103  HOH HOH C . 
T 4 HOH 54  654 166  HOH HOH C . 
T 4 HOH 55  655 454  HOH HOH C . 
T 4 HOH 56  656 436  HOH HOH C . 
T 4 HOH 57  657 448  HOH HOH C . 
T 4 HOH 58  658 14   HOH HOH C . 
T 4 HOH 59  659 404  HOH HOH C . 
T 4 HOH 60  660 141  HOH HOH C . 
T 4 HOH 61  661 105  HOH HOH C . 
T 4 HOH 62  662 456  HOH HOH C . 
T 4 HOH 63  663 47   HOH HOH C . 
T 4 HOH 64  664 464  HOH HOH C . 
T 4 HOH 65  665 213  HOH HOH C . 
T 4 HOH 66  666 453  HOH HOH C . 
T 4 HOH 67  667 108  HOH HOH C . 
T 4 HOH 68  668 616  HOH HOH C . 
T 4 HOH 69  669 459  HOH HOH C . 
T 4 HOH 70  670 112  HOH HOH C . 
T 4 HOH 71  671 415  HOH HOH C . 
T 4 HOH 72  672 176  HOH HOH C . 
T 4 HOH 73  673 85   HOH HOH C . 
T 4 HOH 74  674 20   HOH HOH C . 
T 4 HOH 75  675 450  HOH HOH C . 
T 4 HOH 76  676 1    HOH HOH C . 
T 4 HOH 77  677 461  HOH HOH C . 
T 4 HOH 78  678 460  HOH HOH C . 
T 4 HOH 79  679 442  HOH HOH C . 
T 4 HOH 80  680 447  HOH HOH C . 
T 4 HOH 81  681 39   HOH HOH C . 
T 4 HOH 82  682 30   HOH HOH C . 
T 4 HOH 83  683 471  HOH HOH C . 
T 4 HOH 84  684 470  HOH HOH C . 
T 4 HOH 85  685 218  HOH HOH C . 
T 4 HOH 86  686 473  HOH HOH C . 
T 4 HOH 87  687 90   HOH HOH C . 
U 4 HOH 1   601 222  HOH HOH D . 
U 4 HOH 2   602 16   HOH HOH D . 
U 4 HOH 3   603 29   HOH HOH D . 
U 4 HOH 4   604 527  HOH HOH D . 
U 4 HOH 5   605 195  HOH HOH D . 
U 4 HOH 6   606 66   HOH HOH D . 
U 4 HOH 7   607 522  HOH HOH D . 
U 4 HOH 8   608 511  HOH HOH D . 
U 4 HOH 9   609 63   HOH HOH D . 
U 4 HOH 10  610 513  HOH HOH D . 
U 4 HOH 11  611 152  HOH HOH D . 
U 4 HOH 12  612 81   HOH HOH D . 
U 4 HOH 13  613 521  HOH HOH D . 
U 4 HOH 14  614 506  HOH HOH D . 
U 4 HOH 15  615 425  HOH HOH D . 
U 4 HOH 16  616 532  HOH HOH D . 
U 4 HOH 17  617 56   HOH HOH D . 
U 4 HOH 18  618 76   HOH HOH D . 
U 4 HOH 19  619 135  HOH HOH D . 
U 4 HOH 20  620 533  HOH HOH D . 
U 4 HOH 21  621 503  HOH HOH D . 
U 4 HOH 22  622 539  HOH HOH D . 
U 4 HOH 23  623 555  HOH HOH D . 
U 4 HOH 24  624 33   HOH HOH D . 
U 4 HOH 25  625 172  HOH HOH D . 
U 4 HOH 26  626 553  HOH HOH D . 
U 4 HOH 27  627 547  HOH HOH D . 
U 4 HOH 28  628 544  HOH HOH D . 
U 4 HOH 29  629 535  HOH HOH D . 
U 4 HOH 30  630 540  HOH HOH D . 
U 4 HOH 31  631 512  HOH HOH D . 
U 4 HOH 32  632 557  HOH HOH D . 
U 4 HOH 33  633 537  HOH HOH D . 
U 4 HOH 34  634 161  HOH HOH D . 
U 4 HOH 35  635 520  HOH HOH D . 
U 4 HOH 36  636 507  HOH HOH D . 
U 4 HOH 37  637 529  HOH HOH D . 
U 4 HOH 38  638 208  HOH HOH D . 
U 4 HOH 39  639 65   HOH HOH D . 
U 4 HOH 40  640 562  HOH HOH D . 
U 4 HOH 41  641 97   HOH HOH D . 
U 4 HOH 42  642 561  HOH HOH D . 
U 4 HOH 43  643 523  HOH HOH D . 
U 4 HOH 44  644 155  HOH HOH D . 
U 4 HOH 45  645 534  HOH HOH D . 
U 4 HOH 46  646 554  HOH HOH D . 
U 4 HOH 47  647 68   HOH HOH D . 
U 4 HOH 48  648 11   HOH HOH D . 
U 4 HOH 49  649 558  HOH HOH D . 
U 4 HOH 50  650 18   HOH HOH D . 
U 4 HOH 51  651 72   HOH HOH D . 
U 4 HOH 52  652 565  HOH HOH D . 
U 4 HOH 53  653 174  HOH HOH D . 
U 4 HOH 54  654 110  HOH HOH D . 
U 4 HOH 55  655 519  HOH HOH D . 
U 4 HOH 56  656 550  HOH HOH D . 
U 4 HOH 57  657 31   HOH HOH D . 
U 4 HOH 58  658 111  HOH HOH D . 
U 4 HOH 59  659 542  HOH HOH D . 
U 4 HOH 60  660 79   HOH HOH D . 
U 4 HOH 61  661 132  HOH HOH D . 
U 4 HOH 62  662 87   HOH HOH D . 
U 4 HOH 63  663 569  HOH HOH D . 
U 4 HOH 64  664 568  HOH HOH D . 
U 4 HOH 65  665 129  HOH HOH D . 
U 4 HOH 66  666 536  HOH HOH D . 
U 4 HOH 67  667 86   HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ETP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     73.864 
_cell.length_a_esd                 ? 
_cell.length_b                     133.717 
_cell.length_b_esd                 ? 
_cell.length_c                     147.866 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ETP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ETP 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.80 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.01 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ETP 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.48 
_reflns.d_resolution_low                               147.87 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     50159 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           95.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.187 
_reflns.pdbx_Rpim_I_all                                0.070 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.173 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.48 
_reflns_shell.d_res_low                                     2.56 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2559 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               14.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.320 
_reflns_shell.pdbx_Rpim_I_all                               0.491 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.779 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.225 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -1.338 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            -0.125 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            1.464 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               51.217 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.950 
_refine.correlation_coeff_Fo_to_Fc_free          0.936 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ETP 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.480 
_refine.ls_d_res_low                             99.375 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     50088 
_refine.ls_number_reflns_R_free                  2559 
_refine.ls_number_reflns_R_work                  47529 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.074 
_refine.ls_percent_reflns_R_free                 5.109 
_refine.ls_R_factor_all                          0.202 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2307 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2004 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.509 
_refine.pdbx_overall_ESU_R_Free                  0.264 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.480 
_refine_hist.d_res_low                        99.375 
_refine_hist.number_atoms_solvent             414 
_refine_hist.number_atoms_total               9400 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8902 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         84 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.012  9285  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.751  1.852  12603 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.058  5.000  1113  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 23.372 5.000  46    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.052 10.000 1608  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.399 10.000 402   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.115  0.200  1417  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  6970  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.219  0.200  4582  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.317  0.200  6279  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.150  0.200  508   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.226  0.200  74    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.237  0.200  15    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.878  4.960  4452  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.706  8.902  5565  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.113  5.261  4833  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.463  9.527  7038  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.912  55.743 14402 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.480  2.544  3854 . 178 3676 100.0000 . 0.340 . . 0.339 . . . . . 0.339 . 20 . 0.939 0.925 0.362 
'X-RAY DIFFRACTION' 2.544  2.614  3720 . 189 3531 100.0000 . 0.294 . . 0.292 . . . . . 0.285 . 20 . 0.948 0.935 0.339 
'X-RAY DIFFRACTION' 2.614  2.690  3648 . 88  1854 53.2346  . 0.288 . . 0.288 . . . . . 0.276 . 20 . 0.948 0.945 0.289 
'X-RAY DIFFRACTION' 2.690  2.773  3528 . 162 3366 100.0000 . 0.258 . . 0.256 . . . . . 0.243 . 20 . 0.957 0.939 0.297 
'X-RAY DIFFRACTION' 2.773  2.863  3446 . 175 3271 100.0000 . 0.258 . . 0.257 . . . . . 0.240 . 20 . 0.957 0.955 0.276 
'X-RAY DIFFRACTION' 2.863  2.964  3323 . 161 3162 100.0000 . 0.254 . . 0.251 . . . . . 0.236 . 20 . 0.958 0.936 0.319 
'X-RAY DIFFRACTION' 2.964  3.076  3241 . 187 3054 100.0000 . 0.238 . . 0.235 . . . . . 0.221 . 20 . 0.965 0.951 0.285 
'X-RAY DIFFRACTION' 3.076  3.201  3075 . 162 2913 100.0000 . 0.227 . . 0.225 . . . . . 0.211 . 20 . 0.967 0.958 0.258 
'X-RAY DIFFRACTION' 3.201  3.343  2982 . 150 2832 100.0000 . 0.217 . . 0.215 . . . . . 0.201 . 20 . 0.971 0.957 0.254 
'X-RAY DIFFRACTION' 3.343  3.506  2864 . 106 1871 69.0293  . 0.205 . . 0.203 . . . . . 0.190 . 20 . 0.975 0.968 0.234 
'X-RAY DIFFRACTION' 3.506  3.696  2717 . 138 2579 100.0000 . 0.186 . . 0.185 . . . . . 0.176 . 20 . 0.981 0.972 0.208 
'X-RAY DIFFRACTION' 3.696  3.919  2584 . 149 2435 100.0000 . 0.171 . . 0.169 . . . . . 0.162 . 20 . 0.984 0.977 0.214 
'X-RAY DIFFRACTION' 3.919  4.190  2415 . 132 2283 100.0000 . 0.158 . . 0.156 . . . . . 0.150 . 20 . 0.985 0.979 0.187 
'X-RAY DIFFRACTION' 4.190  4.525  2276 . 114 2162 100.0000 . 0.151 . . 0.149 . . . . . 0.146 . 20 . 0.987 0.979 0.177 
'X-RAY DIFFRACTION' 4.525  4.955  2099 . 115 1984 100.0000 . 0.152 . . 0.150 . . . . . 0.147 . 20 . 0.986 0.981 0.183 
'X-RAY DIFFRACTION' 4.955  5.539  1908 . 86  1822 100.0000 . 0.172 . . 0.171 . . . . . 0.166 . 20 . 0.983 0.978 0.199 
'X-RAY DIFFRACTION' 5.539  6.392  1702 . 85  1617 100.0000 . 0.199 . . 0.198 . . . . . 0.193 . 20 . 0.980 0.976 0.226 
'X-RAY DIFFRACTION' 6.392  7.821  1446 . 74  1372 100.0000 . 0.209 . . 0.209 . . . . . 0.207 . 20 . 0.977 0.974 0.211 
'X-RAY DIFFRACTION' 7.821  11.026 1165 . 62  1103 100.0000 . 0.150 . . 0.149 . . . . . 0.158 . 20 . 0.987 0.987 0.161 
'X-RAY DIFFRACTION' 11.026 99.375 690  . 46  642  99.7101  . 0.248 . . 0.247 . . . . . 0.273 . 20 . 0.957 0.967 0.267 
# 
_struct.entry_id                     9ETP 
_struct.title                        'CDK2-cyclin A in complex with FragLite 1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ETP 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
O N N 3 ? 
P N N 3 ? 
Q N N 3 ? 
R N N 4 ? 
S N N 4 ? 
T N N 4 ? 
U N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CDK2_HUMAN  P24941 ? 1 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
2 UNP CCNA2_BOVIN P30274 ? 2 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ETP A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
2 2 9ETP B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
3 1 9ETP C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
4 2 9ETP D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ETP GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  1  
1 9ETP PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  2  
1 9ETP GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  3  
1 9ETP SER A 4   ? UNP P24941 ? ? 'expression tag' 0   4  
2 9ETP GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 5  
2 9ETP HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 6  
2 9ETP HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 7  
2 9ETP HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 8  
2 9ETP HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 9  
2 9ETP HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 10 
2 9ETP HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 11 
3 9ETP GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  12 
3 9ETP PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  13 
3 9ETP GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  14 
3 9ETP SER C 4   ? UNP P24941 ? ? 'expression tag' 0   15 
4 9ETP GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 16 
4 9ETP HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 17 
4 9ETP HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 18 
4 9ETP HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 19 
4 9ETP HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 20 
4 9ETP HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 21 
4 9ETP HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3520  ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  23810 ? 
2 'ABSA (A^2)' 3670  ? 
2 MORE         -18   ? 
2 'SSA (A^2)'  22880 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,G,H,I,J,K,L,R,S 
2 1 C,D,M,N,O,P,Q,T,U       
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 4   ? GLU A 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P2  AA2 PRO A 49  ? LEU A 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 91  ? SER A 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P4  AA4 PRO A 104 ? HIS A 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P5  AA5 LYS A 133 ? GLN A 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P6  AA6 THR A 169 ? ARG A 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P7  AA7 ALA A 174 ? LEU A 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P8  AA8 THR A 186 ? ARG A 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P9  AA9 SER A 211 ? GLY A 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P10 AB1 GLY A 233 ? MET A 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P11 AB2 ASP A 251 ? VAL A 255 ? ASP A 247 VAL A 251 5 ? 5  
HELX_P HELX_P12 AB3 ASP A 260 ? LEU A 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P13 AB4 SER A 280 ? LEU A 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P14 AB5 ALA A 286 ? GLN A 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P15 AB6 GLY B 1   ? VAL B 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P16 AB7 TYR B 8   ? CYS B 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P17 AB8 THR B 37  ? TYR B 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P18 AB9 GLN B 58  ? MET B 76  ? GLN B 228 MET B 246 1 ? 19 
HELX_P HELX_P19 AC1 LEU B 79  ? GLY B 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P20 AC2 LYS B 82  ? GLU B 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P21 AC3 GLU B 104 ? ILE B 111 ? GLU B 274 ILE B 281 1 ? 8  
HELX_P HELX_P22 AC4 THR B 117 ? LEU B 132 ? THR B 287 LEU B 302 1 ? 16 
HELX_P HELX_P23 AC5 THR B 140 ? PHE B 149 ? THR B 310 PHE B 319 1 ? 10 
HELX_P HELX_P24 AC6 LEU B 150 ? GLN B 152 ? LEU B 320 GLN B 322 5 ? 3  
HELX_P HELX_P25 AC7 ASN B 156 ? SER B 170 ? ASN B 326 SER B 340 1 ? 15 
HELX_P HELX_P26 AC8 ASP B 173 ? LEU B 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P27 AC9 LEU B 181 ? GLY B 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P28 AD1 PRO B 203 ? GLY B 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P29 AD2 THR B 213 ? ALA B 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P30 AD3 PRO B 232 ? HIS B 234 ? PRO B 402 HIS B 404 5 ? 3  
HELX_P HELX_P31 AD4 GLN B 237 ? TYR B 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P32 AD5 LYS B 244 ? HIS B 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P33 AD6 GLY B 250 ? LEU B 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P34 AD7 PRO C 49  ? LEU C 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P35 AD8 LEU C 91  ? SER C 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P36 AD9 PRO C 104 ? HIS C 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P37 AE1 LYS C 133 ? GLN C 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P38 AE2 THR C 169 ? ARG C 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P39 AE3 ALA C 174 ? LEU C 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P40 AE4 THR C 186 ? ARG C 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P41 AE5 SER C 211 ? ARG C 221 ? SER C 207 ARG C 217 1 ? 11 
HELX_P HELX_P42 AE6 ASP C 260 ? LEU C 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P43 AE7 SER C 280 ? LEU C 285 ? SER C 276 LEU C 281 1 ? 6  
HELX_P HELX_P44 AE8 ALA C 286 ? GLN C 291 ? ALA C 282 GLN C 287 5 ? 6  
HELX_P HELX_P45 AE9 GLY D 1   ? VAL D 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P46 AF1 TYR D 8   ? CYS D 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P47 AF2 THR D 37  ? TYR D 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P48 AF3 GLN D 58  ? SER D 74  ? GLN D 228 SER D 244 1 ? 17 
HELX_P HELX_P49 AF4 LEU D 79  ? GLY D 81  ? LEU D 249 GLY D 251 5 ? 3  
HELX_P HELX_P50 AF5 LYS D 82  ? GLU D 99  ? LYS D 252 GLU D 269 1 ? 18 
HELX_P HELX_P51 AF6 GLU D 104 ? ILE D 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P52 AF7 THR D 117 ? ALA D 133 ? THR D 287 ALA D 303 1 ? 17 
HELX_P HELX_P53 AF8 THR D 140 ? PHE D 149 ? THR D 310 PHE D 319 1 ? 10 
HELX_P HELX_P54 AF9 LEU D 150 ? GLN D 152 ? LEU D 320 GLN D 322 5 ? 3  
HELX_P HELX_P55 AG1 ASN D 156 ? ASP D 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P56 AG2 ASP D 173 ? LEU D 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P57 AG3 LEU D 181 ? THR D 198 ? LEU D 351 THR D 368 1 ? 18 
HELX_P HELX_P58 AG4 PRO D 203 ? GLY D 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P59 AG5 LEU D 217 ? ALA D 231 ? LEU D 387 ALA D 401 1 ? 15 
HELX_P HELX_P60 AG6 PRO D 232 ? HIS D 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P61 AG7 GLN D 237 ? TYR D 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P62 AG8 LYS D 244 ? HIS D 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P63 AG9 GLY D 250 ? LEU D 254 ? GLY D 420 LEU D 424 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A TYR 163 C ? ? ? 1_555 A TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.336 ? ? 
covale2 covale both ? A TPO 164 C ? ? ? 1_555 A HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.336 ? ? 
covale3 covale both ? C TYR 163 C ? ? ? 1_555 C TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.336 ? ? 
covale4 covale both ? C TPO 164 C ? ? ? 1_555 C HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.341 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO A 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO C 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 158 A . ? VAL 154 A PRO 159 A ? PRO 155 A 1 -4.69  
2 GLN 153 B . ? GLN 323 B PRO 154 B ? PRO 324 B 1 -1.39  
3 ASP 175 B . ? ASP 345 B PRO 176 B ? PRO 346 B 1 12.59  
4 VAL 158 C . ? VAL 154 C PRO 159 C ? PRO 155 C 1 4.39   
5 GLN 153 D . ? GLN 323 D PRO 154 D ? PRO 324 D 1 -19.56 
6 ASP 175 D . ? ASP 345 D PRO 176 D ? PRO 346 D 1 10.67  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 8   ? GLY A 17  ? PHE A 4   GLY A 13  
AA1 2 GLY A 20  ? ASN A 27  ? GLY A 16  ASN A 23  
AA1 3 VAL A 33  ? ARG A 40  ? VAL A 29  ARG A 36  
AA1 4 LYS A 79  ? GLU A 85  ? LYS A 75  GLU A 81  
AA1 5 LEU A 70  ? HIS A 75  ? LEU A 66  HIS A 71  
AA2 1 GLN A 89  ? ASP A 90  ? GLN A 85  ASP A 86  
AA2 2 LEU A 137 ? ILE A 139 ? LEU A 133 ILE A 135 
AA2 3 ILE A 145 ? LEU A 147 ? ILE A 141 LEU A 143 
AA3 1 VAL A 127 ? LEU A 128 ? VAL A 123 LEU A 124 
AA3 2 ARG A 154 ? ALA A 155 ? ARG A 150 ALA A 151 
AA4 1 PHE C 8   ? GLY C 17  ? PHE C 4   GLY C 13  
AA4 2 GLY C 20  ? ASN C 27  ? GLY C 16  ASN C 23  
AA4 3 VAL C 33  ? ARG C 40  ? VAL C 29  ARG C 36  
AA4 4 LYS C 79  ? GLU C 85  ? LYS C 75  GLU C 81  
AA4 5 LEU C 70  ? HIS C 75  ? LEU C 66  HIS C 71  
AA5 1 GLN C 89  ? ASP C 90  ? GLN C 85  ASP C 86  
AA5 2 LEU C 137 ? ILE C 139 ? LEU C 133 ILE C 135 
AA5 3 ILE C 145 ? LEU C 147 ? ILE C 141 LEU C 143 
AA6 1 VAL C 127 ? LEU C 128 ? VAL C 123 LEU C 124 
AA6 2 ARG C 154 ? ALA C 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 17  ? N GLY A 13  O GLY A 20  ? O GLY A 16  
AA1 2 3 N ALA A 25  ? N ALA A 21  O VAL A 34  ? O VAL A 30  
AA1 3 4 N ALA A 35  ? N ALA A 31  O PHE A 84  ? O PHE A 80  
AA1 4 5 O VAL A 83  ? O VAL A 79  N LEU A 71  ? N LEU A 67  
AA2 1 2 N GLN A 89  ? N GLN A 85  O ILE A 139 ? O ILE A 135 
AA2 2 3 N LEU A 138 ? N LEU A 134 O LYS A 146 ? O LYS A 142 
AA3 1 2 N LEU A 128 ? N LEU A 124 O ARG A 154 ? O ARG A 150 
AA4 1 2 N GLU C 12  ? N GLU C 8   O LYS C 24  ? O LYS C 20  
AA4 2 3 N TYR C 23  ? N TYR C 19  O LEU C 36  ? O LEU C 32  
AA4 3 4 N ALA C 35  ? N ALA C 31  O PHE C 84  ? O PHE C 80  
AA4 4 5 O TYR C 81  ? O TYR C 77  N ILE C 74  ? N ILE C 70  
AA5 1 2 N GLN C 89  ? N GLN C 85  O ILE C 139 ? O ILE C 135 
AA5 2 3 N LEU C 138 ? N LEU C 134 O LYS C 146 ? O LYS C 142 
AA6 1 2 N LEU C 128 ? N LEU C 124 O ARG C 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ETP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             D 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             D 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             D 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                90.48 
_pdbx_validate_rmsd_angle.angle_target_value         102.60 
_pdbx_validate_rmsd_angle.angle_deviation            -12.12 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL A 7   ? ? -102.63 -60.99  
2  1 THR A 72  ? ? -91.29  -145.19 
3  1 ASN A 74  ? ? 57.53   17.43   
4  1 ASP A 127 ? ? -153.35 44.62   
5  1 ASP A 145 ? ? 53.77   85.13   
6  1 TYR A 159 ? ? -114.49 -169.11 
7  1 VAL A 164 ? ? 79.12   126.78  
8  1 SER A 181 ? ? -133.20 -145.05 
9  1 VAL B 175 ? ? 35.31   63.19   
10 1 TRP B 372 ? ? -38.12  121.09  
11 1 VAL C 7   ? ? -129.71 -55.06  
12 1 THR C 41  ? ? -134.52 -78.47  
13 1 THR C 41  ? ? -134.52 -76.20  
14 1 GLN C 85  ? ? -173.71 -179.30 
15 1 ASP C 127 ? ? -153.77 46.19   
16 1 ASP C 145 ? ? 50.60   80.08   
17 1 VAL C 164 ? ? 73.24   128.07  
18 1 MET C 233 ? ? 67.68   70.18   
19 1 PRO C 254 ? ? -81.52  47.28   
20 1 THR C 290 ? ? -121.97 -163.01 
21 1 LEU D 320 ? ? -67.40  2.42    
22 1 SER D 371 ? ? 77.79   151.12  
23 1 TRP D 372 ? ? -38.38  116.40  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 36  ? ? 0.203 'SIDE CHAIN' 
2 1 ARG A 150 ? ? 0.282 'SIDE CHAIN' 
3 1 ARG A 200 ? ? 0.270 'SIDE CHAIN' 
4 1 ARG A 245 ? ? 0.257 'SIDE CHAIN' 
5 1 ARG B 293 ? ? 0.257 'SIDE CHAIN' 
6 1 ARG C 122 ? ? 0.236 'SIDE CHAIN' 
7 1 ARG C 157 ? ? 0.173 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 A TPO 164 A TPO 160 ? THR 'modified residue' 
2 C TPO 164 C TPO 160 ? THR 'modified residue' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       717 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.21 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -3  ? A GLY 1   
2  1 Y 1 A ASP 38  ? A ASP 42  
3  1 Y 1 A THR 39  ? A THR 43  
4  1 Y 1 A GLU 40  ? A GLU 44  
5  1 Y 1 A LEU 298 ? A LEU 302 
6  1 Y 1 C GLY -3  ? C GLY 1   
7  1 Y 1 C PRO -2  ? C PRO 2   
8  1 Y 1 C GLY -1  ? C GLY 3   
9  1 Y 1 C PRO 222 ? C PRO 226 
10 1 Y 1 C ASP 223 ? C ASP 227 
11 1 Y 1 C GLU 224 ? C GLU 228 
12 1 Y 1 C VAL 225 ? C VAL 229 
13 1 Y 1 C PHE 240 ? C PHE 244 
14 1 Y 1 C PRO 241 ? C PRO 245 
15 1 Y 1 C LYS 242 ? C LYS 246 
16 1 Y 1 C TRP 243 ? C TRP 247 
17 1 Y 1 C ALA 244 ? C ALA 248 
18 1 Y 1 C ARG 245 ? C ARG 249 
19 1 Y 1 C GLN 246 ? C GLN 250 
20 1 Y 1 C ASP 247 ? C ASP 251 
21 1 Y 1 C PHE 248 ? C PHE 252 
22 1 Y 1 C SER 249 ? C SER 253 
23 1 Y 1 C LYS 250 ? C LYS 254 
24 1 Y 1 C VAL 251 ? C VAL 255 
25 1 Y 1 C VAL 252 ? C VAL 256 
26 1 Y 1 C ARG 297 ? C ARG 301 
27 1 Y 1 C LEU 298 ? C LEU 302 
28 1 Y 1 D VAL 432 ? D VAL 262 
29 1 Y 1 D HIS 433 ? D HIS 263 
30 1 Y 1 D HIS 434 ? D HIS 264 
31 1 Y 1 D HIS 435 ? D HIS 265 
32 1 Y 1 D HIS 436 ? D HIS 266 
33 1 Y 1 D HIS 437 ? D HIS 267 
34 1 Y 1 D HIS 438 ? D HIS 268 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
BYZ BR4  BR N N 74  
BYZ C4   C  Y N 75  
BYZ C5   C  Y N 76  
BYZ N1   N  Y N 77  
BYZ N2   N  Y N 78  
BYZ C3   C  Y N 79  
BYZ H1   H  N N 80  
BYZ H2   H  N N 81  
BYZ H3   H  N N 82  
CYS N    N  N N 83  
CYS CA   C  N R 84  
CYS C    C  N N 85  
CYS O    O  N N 86  
CYS CB   C  N N 87  
CYS SG   S  N N 88  
CYS OXT  O  N N 89  
CYS H    H  N N 90  
CYS H2   H  N N 91  
CYS HA   H  N N 92  
CYS HB2  H  N N 93  
CYS HB3  H  N N 94  
CYS HG   H  N N 95  
CYS HXT  H  N N 96  
GLN N    N  N N 97  
GLN CA   C  N S 98  
GLN C    C  N N 99  
GLN O    O  N N 100 
GLN CB   C  N N 101 
GLN CG   C  N N 102 
GLN CD   C  N N 103 
GLN OE1  O  N N 104 
GLN NE2  N  N N 105 
GLN OXT  O  N N 106 
GLN H    H  N N 107 
GLN H2   H  N N 108 
GLN HA   H  N N 109 
GLN HB2  H  N N 110 
GLN HB3  H  N N 111 
GLN HG2  H  N N 112 
GLN HG3  H  N N 113 
GLN HE21 H  N N 114 
GLN HE22 H  N N 115 
GLN HXT  H  N N 116 
GLU N    N  N N 117 
GLU CA   C  N S 118 
GLU C    C  N N 119 
GLU O    O  N N 120 
GLU CB   C  N N 121 
GLU CG   C  N N 122 
GLU CD   C  N N 123 
GLU OE1  O  N N 124 
GLU OE2  O  N N 125 
GLU OXT  O  N N 126 
GLU H    H  N N 127 
GLU H2   H  N N 128 
GLU HA   H  N N 129 
GLU HB2  H  N N 130 
GLU HB3  H  N N 131 
GLU HG2  H  N N 132 
GLU HG3  H  N N 133 
GLU HE2  H  N N 134 
GLU HXT  H  N N 135 
GLY N    N  N N 136 
GLY CA   C  N N 137 
GLY C    C  N N 138 
GLY O    O  N N 139 
GLY OXT  O  N N 140 
GLY H    H  N N 141 
GLY H2   H  N N 142 
GLY HA2  H  N N 143 
GLY HA3  H  N N 144 
GLY HXT  H  N N 145 
HIS N    N  N N 146 
HIS CA   C  N S 147 
HIS C    C  N N 148 
HIS O    O  N N 149 
HIS CB   C  N N 150 
HIS CG   C  Y N 151 
HIS ND1  N  Y N 152 
HIS CD2  C  Y N 153 
HIS CE1  C  Y N 154 
HIS NE2  N  Y N 155 
HIS OXT  O  N N 156 
HIS H    H  N N 157 
HIS H2   H  N N 158 
HIS HA   H  N N 159 
HIS HB2  H  N N 160 
HIS HB3  H  N N 161 
HIS HD1  H  N N 162 
HIS HD2  H  N N 163 
HIS HE1  H  N N 164 
HIS HE2  H  N N 165 
HIS HXT  H  N N 166 
HOH O    O  N N 167 
HOH H1   H  N N 168 
HOH H2   H  N N 169 
ILE N    N  N N 170 
ILE CA   C  N S 171 
ILE C    C  N N 172 
ILE O    O  N N 173 
ILE CB   C  N S 174 
ILE CG1  C  N N 175 
ILE CG2  C  N N 176 
ILE CD1  C  N N 177 
ILE OXT  O  N N 178 
ILE H    H  N N 179 
ILE H2   H  N N 180 
ILE HA   H  N N 181 
ILE HB   H  N N 182 
ILE HG12 H  N N 183 
ILE HG13 H  N N 184 
ILE HG21 H  N N 185 
ILE HG22 H  N N 186 
ILE HG23 H  N N 187 
ILE HD11 H  N N 188 
ILE HD12 H  N N 189 
ILE HD13 H  N N 190 
ILE HXT  H  N N 191 
LEU N    N  N N 192 
LEU CA   C  N S 193 
LEU C    C  N N 194 
LEU O    O  N N 195 
LEU CB   C  N N 196 
LEU CG   C  N N 197 
LEU CD1  C  N N 198 
LEU CD2  C  N N 199 
LEU OXT  O  N N 200 
LEU H    H  N N 201 
LEU H2   H  N N 202 
LEU HA   H  N N 203 
LEU HB2  H  N N 204 
LEU HB3  H  N N 205 
LEU HG   H  N N 206 
LEU HD11 H  N N 207 
LEU HD12 H  N N 208 
LEU HD13 H  N N 209 
LEU HD21 H  N N 210 
LEU HD22 H  N N 211 
LEU HD23 H  N N 212 
LEU HXT  H  N N 213 
LYS N    N  N N 214 
LYS CA   C  N S 215 
LYS C    C  N N 216 
LYS O    O  N N 217 
LYS CB   C  N N 218 
LYS CG   C  N N 219 
LYS CD   C  N N 220 
LYS CE   C  N N 221 
LYS NZ   N  N N 222 
LYS OXT  O  N N 223 
LYS H    H  N N 224 
LYS H2   H  N N 225 
LYS HA   H  N N 226 
LYS HB2  H  N N 227 
LYS HB3  H  N N 228 
LYS HG2  H  N N 229 
LYS HG3  H  N N 230 
LYS HD2  H  N N 231 
LYS HD3  H  N N 232 
LYS HE2  H  N N 233 
LYS HE3  H  N N 234 
LYS HZ1  H  N N 235 
LYS HZ2  H  N N 236 
LYS HZ3  H  N N 237 
LYS HXT  H  N N 238 
MET N    N  N N 239 
MET CA   C  N S 240 
MET C    C  N N 241 
MET O    O  N N 242 
MET CB   C  N N 243 
MET CG   C  N N 244 
MET SD   S  N N 245 
MET CE   C  N N 246 
MET OXT  O  N N 247 
MET H    H  N N 248 
MET H2   H  N N 249 
MET HA   H  N N 250 
MET HB2  H  N N 251 
MET HB3  H  N N 252 
MET HG2  H  N N 253 
MET HG3  H  N N 254 
MET HE1  H  N N 255 
MET HE2  H  N N 256 
MET HE3  H  N N 257 
MET HXT  H  N N 258 
PHE N    N  N N 259 
PHE CA   C  N S 260 
PHE C    C  N N 261 
PHE O    O  N N 262 
PHE CB   C  N N 263 
PHE CG   C  Y N 264 
PHE CD1  C  Y N 265 
PHE CD2  C  Y N 266 
PHE CE1  C  Y N 267 
PHE CE2  C  Y N 268 
PHE CZ   C  Y N 269 
PHE OXT  O  N N 270 
PHE H    H  N N 271 
PHE H2   H  N N 272 
PHE HA   H  N N 273 
PHE HB2  H  N N 274 
PHE HB3  H  N N 275 
PHE HD1  H  N N 276 
PHE HD2  H  N N 277 
PHE HE1  H  N N 278 
PHE HE2  H  N N 279 
PHE HZ   H  N N 280 
PHE HXT  H  N N 281 
PRO N    N  N N 282 
PRO CA   C  N S 283 
PRO C    C  N N 284 
PRO O    O  N N 285 
PRO CB   C  N N 286 
PRO CG   C  N N 287 
PRO CD   C  N N 288 
PRO OXT  O  N N 289 
PRO H    H  N N 290 
PRO HA   H  N N 291 
PRO HB2  H  N N 292 
PRO HB3  H  N N 293 
PRO HG2  H  N N 294 
PRO HG3  H  N N 295 
PRO HD2  H  N N 296 
PRO HD3  H  N N 297 
PRO HXT  H  N N 298 
SER N    N  N N 299 
SER CA   C  N S 300 
SER C    C  N N 301 
SER O    O  N N 302 
SER CB   C  N N 303 
SER OG   O  N N 304 
SER OXT  O  N N 305 
SER H    H  N N 306 
SER H2   H  N N 307 
SER HA   H  N N 308 
SER HB2  H  N N 309 
SER HB3  H  N N 310 
SER HG   H  N N 311 
SER HXT  H  N N 312 
THR N    N  N N 313 
THR CA   C  N S 314 
THR C    C  N N 315 
THR O    O  N N 316 
THR CB   C  N R 317 
THR OG1  O  N N 318 
THR CG2  C  N N 319 
THR OXT  O  N N 320 
THR H    H  N N 321 
THR H2   H  N N 322 
THR HA   H  N N 323 
THR HB   H  N N 324 
THR HG1  H  N N 325 
THR HG21 H  N N 326 
THR HG22 H  N N 327 
THR HG23 H  N N 328 
THR HXT  H  N N 329 
TPO N    N  N N 330 
TPO CA   C  N S 331 
TPO CB   C  N R 332 
TPO CG2  C  N N 333 
TPO OG1  O  N N 334 
TPO P    P  N N 335 
TPO O1P  O  N N 336 
TPO O2P  O  N N 337 
TPO O3P  O  N N 338 
TPO C    C  N N 339 
TPO O    O  N N 340 
TPO OXT  O  N N 341 
TPO H    H  N N 342 
TPO H2   H  N N 343 
TPO HA   H  N N 344 
TPO HB   H  N N 345 
TPO HG21 H  N N 346 
TPO HG22 H  N N 347 
TPO HG23 H  N N 348 
TPO HOP2 H  N N 349 
TPO HOP3 H  N N 350 
TPO HXT  H  N N 351 
TRP N    N  N N 352 
TRP CA   C  N S 353 
TRP C    C  N N 354 
TRP O    O  N N 355 
TRP CB   C  N N 356 
TRP CG   C  Y N 357 
TRP CD1  C  Y N 358 
TRP CD2  C  Y N 359 
TRP NE1  N  Y N 360 
TRP CE2  C  Y N 361 
TRP CE3  C  Y N 362 
TRP CZ2  C  Y N 363 
TRP CZ3  C  Y N 364 
TRP CH2  C  Y N 365 
TRP OXT  O  N N 366 
TRP H    H  N N 367 
TRP H2   H  N N 368 
TRP HA   H  N N 369 
TRP HB2  H  N N 370 
TRP HB3  H  N N 371 
TRP HD1  H  N N 372 
TRP HE1  H  N N 373 
TRP HE3  H  N N 374 
TRP HZ2  H  N N 375 
TRP HZ3  H  N N 376 
TRP HH2  H  N N 377 
TRP HXT  H  N N 378 
TYR N    N  N N 379 
TYR CA   C  N S 380 
TYR C    C  N N 381 
TYR O    O  N N 382 
TYR CB   C  N N 383 
TYR CG   C  Y N 384 
TYR CD1  C  Y N 385 
TYR CD2  C  Y N 386 
TYR CE1  C  Y N 387 
TYR CE2  C  Y N 388 
TYR CZ   C  Y N 389 
TYR OH   O  N N 390 
TYR OXT  O  N N 391 
TYR H    H  N N 392 
TYR H2   H  N N 393 
TYR HA   H  N N 394 
TYR HB2  H  N N 395 
TYR HB3  H  N N 396 
TYR HD1  H  N N 397 
TYR HD2  H  N N 398 
TYR HE1  H  N N 399 
TYR HE2  H  N N 400 
TYR HH   H  N N 401 
TYR HXT  H  N N 402 
VAL N    N  N N 403 
VAL CA   C  N S 404 
VAL C    C  N N 405 
VAL O    O  N N 406 
VAL CB   C  N N 407 
VAL CG1  C  N N 408 
VAL CG2  C  N N 409 
VAL OXT  O  N N 410 
VAL H    H  N N 411 
VAL H2   H  N N 412 
VAL HA   H  N N 413 
VAL HB   H  N N 414 
VAL HG11 H  N N 415 
VAL HG12 H  N N 416 
VAL HG13 H  N N 417 
VAL HG21 H  N N 418 
VAL HG22 H  N N 419 
VAL HG23 H  N N 420 
VAL HXT  H  N N 421 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BYZ N2  C3   doub Y N 70  
BYZ N2  N1   sing Y N 71  
BYZ C3  C4   sing Y N 72  
BYZ N1  C5   sing Y N 73  
BYZ C4  C5   doub Y N 74  
BYZ C4  BR4  sing N N 75  
BYZ C5  H1   sing N N 76  
BYZ N1  H2   sing N N 77  
BYZ C3  H3   sing N N 78  
CYS N   CA   sing N N 79  
CYS N   H    sing N N 80  
CYS N   H2   sing N N 81  
CYS CA  C    sing N N 82  
CYS CA  CB   sing N N 83  
CYS CA  HA   sing N N 84  
CYS C   O    doub N N 85  
CYS C   OXT  sing N N 86  
CYS CB  SG   sing N N 87  
CYS CB  HB2  sing N N 88  
CYS CB  HB3  sing N N 89  
CYS SG  HG   sing N N 90  
CYS OXT HXT  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PHE N   CA   sing N N 246 
PHE N   H    sing N N 247 
PHE N   H2   sing N N 248 
PHE CA  C    sing N N 249 
PHE CA  CB   sing N N 250 
PHE CA  HA   sing N N 251 
PHE C   O    doub N N 252 
PHE C   OXT  sing N N 253 
PHE CB  CG   sing N N 254 
PHE CB  HB2  sing N N 255 
PHE CB  HB3  sing N N 256 
PHE CG  CD1  doub Y N 257 
PHE CG  CD2  sing Y N 258 
PHE CD1 CE1  sing Y N 259 
PHE CD1 HD1  sing N N 260 
PHE CD2 CE2  doub Y N 261 
PHE CD2 HD2  sing N N 262 
PHE CE1 CZ   doub Y N 263 
PHE CE1 HE1  sing N N 264 
PHE CE2 CZ   sing Y N 265 
PHE CE2 HE2  sing N N 266 
PHE CZ  HZ   sing N N 267 
PHE OXT HXT  sing N N 268 
PRO N   CA   sing N N 269 
PRO N   CD   sing N N 270 
PRO N   H    sing N N 271 
PRO CA  C    sing N N 272 
PRO CA  CB   sing N N 273 
PRO CA  HA   sing N N 274 
PRO C   O    doub N N 275 
PRO C   OXT  sing N N 276 
PRO CB  CG   sing N N 277 
PRO CB  HB2  sing N N 278 
PRO CB  HB3  sing N N 279 
PRO CG  CD   sing N N 280 
PRO CG  HG2  sing N N 281 
PRO CG  HG3  sing N N 282 
PRO CD  HD2  sing N N 283 
PRO CD  HD3  sing N N 284 
PRO OXT HXT  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
THR N   CA   sing N N 299 
THR N   H    sing N N 300 
THR N   H2   sing N N 301 
THR CA  C    sing N N 302 
THR CA  CB   sing N N 303 
THR CA  HA   sing N N 304 
THR C   O    doub N N 305 
THR C   OXT  sing N N 306 
THR CB  OG1  sing N N 307 
THR CB  CG2  sing N N 308 
THR CB  HB   sing N N 309 
THR OG1 HG1  sing N N 310 
THR CG2 HG21 sing N N 311 
THR CG2 HG22 sing N N 312 
THR CG2 HG23 sing N N 313 
THR OXT HXT  sing N N 314 
TPO N   CA   sing N N 315 
TPO N   H    sing N N 316 
TPO N   H2   sing N N 317 
TPO CA  CB   sing N N 318 
TPO CA  C    sing N N 319 
TPO CA  HA   sing N N 320 
TPO CB  CG2  sing N N 321 
TPO CB  OG1  sing N N 322 
TPO CB  HB   sing N N 323 
TPO CG2 HG21 sing N N 324 
TPO CG2 HG22 sing N N 325 
TPO CG2 HG23 sing N N 326 
TPO OG1 P    sing N N 327 
TPO P   O1P  doub N N 328 
TPO P   O2P  sing N N 329 
TPO P   O3P  sing N N 330 
TPO O2P HOP2 sing N N 331 
TPO O3P HOP3 sing N N 332 
TPO C   O    doub N N 333 
TPO C   OXT  sing N N 334 
TPO OXT HXT  sing N N 335 
TRP N   CA   sing N N 336 
TRP N   H    sing N N 337 
TRP N   H2   sing N N 338 
TRP CA  C    sing N N 339 
TRP CA  CB   sing N N 340 
TRP CA  HA   sing N N 341 
TRP C   O    doub N N 342 
TRP C   OXT  sing N N 343 
TRP CB  CG   sing N N 344 
TRP CB  HB2  sing N N 345 
TRP CB  HB3  sing N N 346 
TRP CG  CD1  doub Y N 347 
TRP CG  CD2  sing Y N 348 
TRP CD1 NE1  sing Y N 349 
TRP CD1 HD1  sing N N 350 
TRP CD2 CE2  doub Y N 351 
TRP CD2 CE3  sing Y N 352 
TRP NE1 CE2  sing Y N 353 
TRP NE1 HE1  sing N N 354 
TRP CE2 CZ2  sing Y N 355 
TRP CE3 CZ3  doub Y N 356 
TRP CE3 HE3  sing N N 357 
TRP CZ2 CH2  doub Y N 358 
TRP CZ2 HZ2  sing N N 359 
TRP CZ3 CH2  sing Y N 360 
TRP CZ3 HZ3  sing N N 361 
TRP CH2 HH2  sing N N 362 
TRP OXT HXT  sing N N 363 
TYR N   CA   sing N N 364 
TYR N   H    sing N N 365 
TYR N   H2   sing N N 366 
TYR CA  C    sing N N 367 
TYR CA  CB   sing N N 368 
TYR CA  HA   sing N N 369 
TYR C   O    doub N N 370 
TYR C   OXT  sing N N 371 
TYR CB  CG   sing N N 372 
TYR CB  HB2  sing N N 373 
TYR CB  HB3  sing N N 374 
TYR CG  CD1  doub Y N 375 
TYR CG  CD2  sing Y N 376 
TYR CD1 CE1  sing Y N 377 
TYR CD1 HD1  sing N N 378 
TYR CD2 CE2  doub Y N 379 
TYR CD2 HD2  sing N N 380 
TYR CE1 CZ   doub Y N 381 
TYR CE1 HE1  sing N N 382 
TYR CE2 CZ   sing Y N 383 
TYR CE2 HE2  sing N N 384 
TYR CZ  OH   sing N N 385 
TYR OH  HH   sing N N 386 
TYR OXT HXT  sing N N 387 
VAL N   CA   sing N N 388 
VAL N   H    sing N N 389 
VAL N   H2   sing N N 390 
VAL CA  C    sing N N 391 
VAL CA  CB   sing N N 392 
VAL CA  HA   sing N N 393 
VAL C   O    doub N N 394 
VAL C   OXT  sing N N 395 
VAL CB  CG1  sing N N 396 
VAL CB  CG2  sing N N 397 
VAL CB  HB   sing N N 398 
VAL CG1 HG11 sing N N 399 
VAL CG1 HG12 sing N N 400 
VAL CG1 HG13 sing N N 401 
VAL CG2 HG21 sing N N 402 
VAL CG2 HG22 sing N N 403 
VAL CG2 HG23 sing N N 404 
VAL OXT HXT  sing N N 405 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ETP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013538 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007478 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006763 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 -0.0527  
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P  15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . PRO A 1 2   ? -21.293 -6.529  26.399  1   95.35  ? -2  PRO A N   1 
ATOM   2    C  CA  . PRO A 1 2   ? -22.073 -7.486  27.19   1   96.39  ? -2  PRO A CA  1 
ATOM   3    C  C   . PRO A 1 2   ? -21.447 -7.941  28.52   1   89.52  ? -2  PRO A C   1 
ATOM   4    O  O   . PRO A 1 2   ? -22.145 -8.071  29.528  1   82.09  ? -2  PRO A O   1 
ATOM   5    C  CB  . PRO A 1 2   ? -22.377 -8.655  26.209  1   93.42  ? -2  PRO A CB  1 
ATOM   6    C  CG  . PRO A 1 2   ? -22.097 -8.07   24.815  1   97.57  ? -2  PRO A CG  1 
ATOM   7    C  CD  . PRO A 1 2   ? -21.53  -6.654  24.957  1   92.18  ? -2  PRO A CD  1 
ATOM   8    N  N   . GLY A 1 3   ? -20.116 -7.986  28.561  1   83.01  ? -1  GLY A N   1 
ATOM   9    C  CA  . GLY A 1 3   ? -19.437 -8.355  29.814  1   80.9   ? -1  GLY A CA  1 
ATOM   10   C  C   . GLY A 1 3   ? -18.423 -7.333  30.277  1   86.77  ? -1  GLY A C   1 
ATOM   11   O  O   . GLY A 1 3   ? -18.354 -6.257  29.662  1   87.65  ? -1  GLY A O   1 
ATOM   12   N  N   . SER A 1 4   ? -17.671 -7.656  31.331  1   93.51  ? 0   SER A N   1 
ATOM   13   C  CA  . SER A 1 4   ? -16.628 -6.764  31.901  1   89.63  ? 0   SER A CA  1 
ATOM   14   C  C   . SER A 1 4   ? -15.505 -7.639  32.468  1   80.9   ? 0   SER A C   1 
ATOM   15   O  O   . SER A 1 4   ? -15.791 -8.799  32.805  1   81.99  ? 0   SER A O   1 
ATOM   16   C  CB  . SER A 1 4   ? -17.213 -5.893  32.963  1   97.44  ? 0   SER A CB  1 
ATOM   17   O  OG  . SER A 1 4   ? -17.118 -6.524  34.232  1   100.59 ? 0   SER A OG  1 
ATOM   18   N  N   . MET A 1 5   ? -14.297 -7.102  32.634  1   71.84  ? 1   MET A N   1 
ATOM   19   C  CA  . MET A 1 5   ? -13.149 -7.956  33.044  1   64.24  ? 1   MET A CA  1 
ATOM   20   C  C   . MET A 1 5   ? -13.164 -8.265  34.547  1   60.78  ? 1   MET A C   1 
ATOM   21   O  O   . MET A 1 5   ? -12.486 -9.218  34.951  1   57.98  ? 1   MET A O   1 
ATOM   22   C  CB  . MET A 1 5   ? -11.826 -7.299  32.648  1   63.09  ? 1   MET A CB  1 
ATOM   23   C  CG  . MET A 1 5   ? -11.54  -7.382  31.169  1   57.85  ? 1   MET A CG  1 
ATOM   24   S  SD  . MET A 1 5   ? -12.309 -8.835  30.432  1   54.81  ? 1   MET A SD  1 
ATOM   25   C  CE  . MET A 1 5   ? -11.024 -10.055 30.718  1   50.8   ? 1   MET A CE  1 
ATOM   26   N  N   . GLU A 1 6   ? -13.912 -7.495  35.327  1   60.06  ? 2   GLU A N   1 
ATOM   27   C  CA  . GLU A 1 6   ? -14.01  -7.735  36.786  1   64.12  ? 2   GLU A CA  1 
ATOM   28   C  C   . GLU A 1 6   ? -14.57  -9.133  37.064  1   59.88  ? 2   GLU A C   1 
ATOM   29   O  O   . GLU A 1 6   ? -14.081 -9.778  38.001  1   59.97  ? 2   GLU A O   1 
ATOM   30   C  CB  . GLU A 1 6   ? -14.919 -6.686  37.419  1   69.74  ? 2   GLU A CB  1 
ATOM   31   C  CG  . GLU A 1 6   ? -15.219 -6.94   38.894  1   80.44  ? 2   GLU A CG  1 
ATOM   32   C  CD  . GLU A 1 6   ? -14.006 -7.077  39.798  1   85.78  ? 2   GLU A CD  1 
ATOM   33   O  OE1 . GLU A 1 6   ? -14.079 -7.901  40.729  1   91.36  ? 2   GLU A OE1 1 
ATOM   34   O  OE2 . GLU A 1 6   ? -12.996 -6.376  39.582  1   84.34  ? 2   GLU A OE2 1 
ATOM   35   N  N   . ASN A 1 7   ? -15.54  -9.583  36.275  1   55.72  ? 3   ASN A N   1 
ATOM   36   C  CA  . ASN A 1 7   ? -16.192 -10.887 36.565  1   54.88  ? 3   ASN A CA  1 
ATOM   37   C  C   . ASN A 1 7   ? -15.341 -12.058 36.059  1   50.76  ? 3   ASN A C   1 
ATOM   38   O  O   . ASN A 1 7   ? -15.801 -13.196 36.202  1   49.47  ? 3   ASN A O   1 
ATOM   39   C  CB  . ASN A 1 7   ? -17.625 -10.91  36.049  1   56.37  ? 3   ASN A CB  1 
ATOM   40   C  CG  . ASN A 1 7   ? -18.486 -9.866  36.711  1   61.93  ? 3   ASN A CG  1 
ATOM   41   O  OD1 . ASN A 1 7   ? -18.41  -9.678  37.93   1   64.67  ? 3   ASN A OD1 1 
ATOM   42   N  ND2 . ASN A 1 7   ? -19.31  -9.184  35.93   1   60.84  ? 3   ASN A ND2 1 
ATOM   43   N  N   . PHE A 1 8   ? -14.139 -11.802 35.542  1   48.63  ? 4   PHE A N   1 
ATOM   44   C  CA  . PHE A 1 8   ? -13.301 -12.913 35.125  1   46.66  ? 4   PHE A CA  1 
ATOM   45   C  C   . PHE A 1 8   ? -12.106 -13.074 36.061  1   50.25  ? 4   PHE A C   1 
ATOM   46   O  O   . PHE A 1 8   ? -11.409 -12.116 36.392  1   54.73  ? 4   PHE A O   1 
ATOM   47   C  CB  . PHE A 1 8   ? -12.882 -12.708 33.675  1   43.07  ? 4   PHE A CB  1 
ATOM   48   C  CG  . PHE A 1 8   ? -14.034 -12.884 32.7    1   41.14  ? 4   PHE A CG  1 
ATOM   49   C  CD1 . PHE A 1 8   ? -14.515 -14.143 32.377  1   39.61  ? 4   PHE A CD1 1 
ATOM   50   C  CD2 . PHE A 1 8   ? -14.619 -11.79  32.074  1   42.98  ? 4   PHE A CD2 1 
ATOM   51   C  CE1 . PHE A 1 8   ? -15.547 -14.312 31.458  1   39.19  ? 4   PHE A CE1 1 
ATOM   52   C  CE2 . PHE A 1 8   ? -15.633 -11.961 31.131  1   42.32  ? 4   PHE A CE2 1 
ATOM   53   C  CZ  . PHE A 1 8   ? -16.1   -13.224 30.823  1   39.28  ? 4   PHE A CZ  1 
ATOM   54   N  N   . GLN A 1 9   ? -11.908 -14.312 36.516  1   51.46  ? 5   GLN A N   1 
ATOM   55   C  CA  . GLN A 1 9   ? -10.748 -14.713 37.294  1   54.09  ? 5   GLN A CA  1 
ATOM   56   C  C   . GLN A 1 9   ? -9.747  -15.388 36.357  1   51.85  ? 5   GLN A C   1 
ATOM   57   O  O   . GLN A 1 9   ? -10.063 -16.392 35.727  1   47.69  ? 5   GLN A O   1 
ATOM   58   C  CB  . GLN A 1 9   ? -11.216 -15.68  38.379  1   57.33  ? 5   GLN A CB  1 
ATOM   59   C  CG  . GLN A 1 9   ? -10.092 -16.413 39.101  1   61.95  ? 5   GLN A CG  1 
ATOM   60   C  CD  . GLN A 1 9   ? -9.417  -15.554 40.137  1   69.2   ? 5   GLN A CD  1 
ATOM   61   O  OE1 . GLN A 1 9   ? -9.852  -15.48  41.295  1   72.95  ? 5   GLN A OE1 1 
ATOM   62   N  NE2 . GLN A 1 9   ? -8.343  -14.897 39.71   1   71.45  ? 5   GLN A NE2 1 
ATOM   63   N  N   . LYS A 1 10  ? -8.541  -14.814 36.259  1   55.42  ? 6   LYS A N   1 
ATOM   64   C  CA  . LYS A 1 10  ? -7.477  -15.387 35.446  1   57.32  ? 6   LYS A CA  1 
ATOM   65   C  C   . LYS A 1 10  ? -6.989  -16.651 36.148  1   57.87  ? 6   LYS A C   1 
ATOM   66   O  O   . LYS A 1 10  ? -6.772  -16.62  37.35   1   61.16  ? 6   LYS A O   1 
ATOM   67   C  CB  . LYS A 1 10  ? -6.387  -14.321 35.334  1   61.86  ? 6   LYS A CB  1 
ATOM   68   C  CG  . LYS A 1 10  ? -5.513  -14.373 34.104  1   65.78  ? 6   LYS A CG  1 
ATOM   69   C  CD  . LYS A 1 10  ? -4.776  -13.088 33.711  1   69.9   ? 6   LYS A CD  1 
ATOM   70   C  CE  . LYS A 1 10  ? -3.624  -12.615 34.548  1   72.26  ? 6   LYS A CE  1 
ATOM   71   N  NZ  . LYS A 1 10  ? -2.864  -11.587 33.826  1   70.06  ? 6   LYS A NZ  1 
ATOM   72   N  N   . VAL A 1 11  ? -6.871  -17.765 35.416  1   56.94  ? 7   VAL A N   1 
ATOM   73   C  CA  . VAL A 1 11  ? -6.477  -19.044 35.999  1   59.48  ? 7   VAL A CA  1 
ATOM   74   C  C   . VAL A 1 11  ? -5.006  -19.332 35.678  1   60.24  ? 7   VAL A C   1 
ATOM   75   O  O   . VAL A 1 11  ? -4.197  -19.474 36.578  1   66.71  ? 7   VAL A O   1 
ATOM   76   C  CB  . VAL A 1 11  ? -7.382  -20.242 35.63   1   58.4   ? 7   VAL A CB  1 
ATOM   77   C  CG1 . VAL A 1 11  ? -6.736  -21.573 35.984  1   55.28  ? 7   VAL A CG1 1 
ATOM   78   C  CG2 . VAL A 1 11  ? -8.75   -20.154 36.282  1   57.78  ? 7   VAL A CG2 1 
ATOM   79   N  N   . GLU A 1 12  ? -4.654  -19.438 34.397  1   56.93  ? 8   GLU A N   1 
ATOM   80   C  CA  . GLU A 1 12  ? -3.283  -19.726 34.027  1   57.14  ? 8   GLU A CA  1 
ATOM   81   C  C   . GLU A 1 12  ? -3.099  -19.449 32.536  1   57.43  ? 8   GLU A C   1 
ATOM   82   O  O   . GLU A 1 12  ? -4.077  -19.361 31.785  1   55.1   ? 8   GLU A O   1 
ATOM   83   C  CB  . GLU A 1 12  ? -3.021  -21.206 34.29   1   59.1   ? 8   GLU A CB  1 
ATOM   84   C  CG  . GLU A 1 12  ? -3.756  -22.122 33.316  1   59.05  ? 8   GLU A CG  1 
ATOM   85   C  CD  . GLU A 1 12  ? -3.795  -23.571 33.75   1   62.34  ? 8   GLU A CD  1 
ATOM   86   O  OE1 . GLU A 1 12  ? -3.597  -23.798 34.959  1   66.66  ? 8   GLU A OE1 1 
ATOM   87   O  OE2 . GLU A 1 12  ? -3.976  -24.466 32.892  1   62.35  ? 8   GLU A OE2 1 
ATOM   88   N  N   . LYS A 1 13  ? -1.835  -19.307 32.115  1   56.44  ? 9   LYS A N   1 
ATOM   89   C  CA  . LYS A 1 13  ? -1.551  -19.128 30.706  1   56.3   ? 9   LYS A CA  1 
ATOM   90   C  C   . LYS A 1 13  ? -1.876  -20.453 30.028  1   55.39  ? 9   LYS A C   1 
ATOM   91   O  O   . LYS A 1 13  ? -1.575  -21.513 30.561  1   60.46  ? 9   LYS A O   1 
ATOM   92   C  CB  . LYS A 1 13  ? -0.117  -18.631 30.496  1   57.47  ? 9   LYS A CB  1 
ATOM   93   C  CG  . LYS A 1 13  ? 0.339   -18.653 29.046  1   61.39  ? 9   LYS A CG  1 
ATOM   94   C  CD  . LYS A 1 13  ? 1.816   -18.358 28.761  1   72.8   ? 9   LYS A CD  1 
ATOM   95   C  CE  . LYS A 1 13  ? 2.17    -18.706 27.323  1   76.34  ? 9   LYS A CE  1 
ATOM   96   N  NZ  . LYS A 1 13  ? 3.541   -18.464 26.847  1   75.32  ? 9   LYS A NZ  1 
ATOM   97   N  N   . ILE A 1 14  ? -2.588  -20.378 28.913  1   52.95  ? 10  ILE A N   1 
ATOM   98   C  CA  . ILE A 1 14  ? -2.945  -21.538 28.117  1   55.28  ? 10  ILE A CA  1 
ATOM   99   C  C   . ILE A 1 14  ? -1.91   -21.691 27.01   1   60.05  ? 10  ILE A C   1 
ATOM   100  O  O   . ILE A 1 14  ? -1.434  -22.786 26.735  1   66.38  ? 10  ILE A O   1 
ATOM   101  C  CB  . ILE A 1 14  ? -4.291  -21.294 27.417  1   55.93  ? 10  ILE A CB  1 
ATOM   102  C  CG1 . ILE A 1 14  ? -5.506  -21.426 28.306  1   56.82  ? 10  ILE A CG1 1 
ATOM   103  C  CG2 . ILE A 1 14  ? -4.405  -22.173 26.177  1   60.82  ? 10  ILE A CG2 1 
ATOM   104  C  CD1 . ILE A 1 14  ? -6.799  -21.233 27.53   1   50.88  ? 10  ILE A CD1 1 
ATOM   105  N  N   . GLY A 1 15  ? -1.646  -20.583 26.31   1   60.71  ? 11  GLY A N   1 
ATOM   106  C  CA  . GLY A 1 15  ? -0.946  -20.6   25.041  1   58.85  ? 11  GLY A CA  1 
ATOM   107  C  C   . GLY A 1 15  ? -0.521  -19.191 24.645  1   63.48  ? 11  GLY A C   1 
ATOM   108  O  O   . GLY A 1 15  ? -0.46   -18.287 25.477  1   63.55  ? 11  GLY A O   1 
ATOM   109  N  N   . GLU A 1 16  ? -0.184  -19.034 23.367  1   67.05  ? 12  GLU A N   1 
ATOM   110  C  CA  . GLU A 1 16  ? 0.348   -17.791 22.834  1   72.19  ? 12  GLU A CA  1 
ATOM   111  C  C   . GLU A 1 16  ? -0.06   -17.704 21.378  1   71.77  ? 12  GLU A C   1 
ATOM   112  O  O   . GLU A 1 16  ? 0.353   -18.54  20.59   1   73.45  ? 12  GLU A O   1 
ATOM   113  C  CB  . GLU A 1 16  ? 1.873   -17.764 22.829  1   78.27  ? 12  GLU A CB  1 
ATOM   114  C  CG  . GLU A 1 16  ? 2.477   -16.694 23.736  1   87.98  ? 12  GLU A CG  1 
ATOM   115  C  CD  . GLU A 1 16  ? 3.988   -16.83  23.773  1   97.38  ? 12  GLU A CD  1 
ATOM   116  O  OE1 . GLU A 1 16  ? 4.471   -17.833 23.187  1   98.5   ? 12  GLU A OE1 1 
ATOM   117  O  OE2 . GLU A 1 16  ? 4.675   -15.951 24.356  1   100.88 ? 12  GLU A OE2 1 
ATOM   118  N  N   . GLY A 1 17  ? -0.904  -16.723 21.057  1   80.67  ? 13  GLY A N   1 
ATOM   119  C  CA  . GLY A 1 17  ? -1.589  -16.7   19.777  1   84.45  ? 13  GLY A CA  1 
ATOM   120  C  C   . GLY A 1 17  ? -1.135  -15.501 18.954  1   90.36  ? 13  GLY A C   1 
ATOM   121  O  O   . GLY A 1 17  ? 0       -15.032 19.089  1   94.22  ? 13  GLY A O   1 
ATOM   122  N  N   . THR A 1 18  ? -2.062  -14.981 18.146  1   80.48  ? 14  THR A N   1 
ATOM   123  C  CA  . THR A 1 18  ? -1.748  -13.899 17.227  1   77.12  ? 14  THR A CA  1 
ATOM   124  C  C   . THR A 1 18  ? -1.566  -12.569 17.976  1   75.19  ? 14  THR A C   1 
ATOM   125  O  O   . THR A 1 18  ? -0.932  -11.644 17.457  1   69.46  ? 14  THR A O   1 
ATOM   126  C  CB  . THR A 1 18  ? -2.831  -13.857 16.148  1   71.54  ? 14  THR A CB  1 
ATOM   127  O  OG1 . THR A 1 18  ? -3.096  -15.222 15.814  1   72.81  ? 14  THR A OG1 1 
ATOM   128  C  CG2 . THR A 1 18  ? -2.428  -13.011 14.953  1   67.18  ? 14  THR A CG2 1 
ATOM   129  N  N   . TYR A 1 19  ? -2.106  -12.481 19.205  1   70.89  ? 15  TYR A N   1 
ATOM   130  C  CA  . TYR A 1 19  ? -2.17   -11.215 19.926  1   76.89  ? 15  TYR A CA  1 
ATOM   131  C  C   . TYR A 1 19  ? -1.319  -11.306 21.186  1   80.98  ? 15  TYR A C   1 
ATOM   132  O  O   . TYR A 1 19  ? -1.424  -10.485 22.099  1   83.21  ? 15  TYR A O   1 
ATOM   133  C  CB  . TYR A 1 19  ? -3.621  -10.834 20.247  1   79.49  ? 15  TYR A CB  1 
ATOM   134  C  CG  . TYR A 1 19  ? -4.533  -11.047 19.049  1   77.82  ? 15  TYR A CG  1 
ATOM   135  C  CD1 . TYR A 1 19  ? -4.408  -10.245 17.912  1   72.45  ? 15  TYR A CD1 1 
ATOM   136  C  CD2 . TYR A 1 19  ? -5.469  -12.081 19.034  1   77.52  ? 15  TYR A CD2 1 
ATOM   137  C  CE1 . TYR A 1 19  ? -5.198  -10.454 16.796  1   66.19  ? 15  TYR A CE1 1 
ATOM   138  C  CE2 . TYR A 1 19  ? -6.268  -12.297 17.921  1   76.06  ? 15  TYR A CE2 1 
ATOM   139  C  CZ  . TYR A 1 19  ? -6.123  -11.486 16.804  1   68.72  ? 15  TYR A CZ  1 
ATOM   140  O  OH  . TYR A 1 19  ? -6.904  -11.686 15.708  1   65.35  ? 15  TYR A OH  1 
ATOM   141  N  N   . GLY A 1 20  ? -0.441  -12.305 21.193  1   83.75  ? 16  GLY A N   1 
ATOM   142  C  CA  . GLY A 1 20  ? 0.287   -12.646 22.394  1   81.95  ? 16  GLY A CA  1 
ATOM   143  C  C   . GLY A 1 20  ? -0.496  -13.718 23.13   1   76.96  ? 16  GLY A C   1 
ATOM   144  O  O   . GLY A 1 20  ? -1.198  -14.515 22.507  1   72.95  ? 16  GLY A O   1 
ATOM   145  N  N   . VAL A 1 21  ? -0.34   -13.737 24.451  1   72.27  ? 17  VAL A N   1 
ATOM   146  C  CA  . VAL A 1 21  ? -0.85   -14.854 25.292  1   70.91  ? 17  VAL A CA  1 
ATOM   147  C  C   . VAL A 1 21  ? -2.364  -15.067 25.307  1   69.04  ? 17  VAL A C   1 
ATOM   148  O  O   . VAL A 1 21  ? -3.119  -14.089 25.18   1   69.66  ? 17  VAL A O   1 
ATOM   149  C  CB  . VAL A 1 21  ? -0.297  -14.565 26.702  1   76.22  ? 17  VAL A CB  1 
ATOM   150  C  CG1 . VAL A 1 21  ? -0.446  -13.102 27.09   1   81.96  ? 17  VAL A CG1 1 
ATOM   151  C  CG2 . VAL A 1 21  ? -0.872  -15.475 27.777  1   80.47  ? 17  VAL A CG2 1 
ATOM   152  N  N   . VAL A 1 22  ? -2.76   -16.332 25.427  1   57.83  ? 18  VAL A N   1 
ATOM   153  C  CA  . VAL A 1 22  ? -4.193  -16.67  25.611  1   51.86  ? 18  VAL A CA  1 
ATOM   154  C  C   . VAL A 1 22  ? -4.263  -17.155 27.06   1   51.15  ? 18  VAL A C   1 
ATOM   155  O  O   . VAL A 1 22  ? -3.335  -17.854 27.487  1   55.48  ? 18  VAL A O   1 
ATOM   156  C  CB  . VAL A 1 22  ? -4.697  -17.742 24.629  1   49.08  ? 18  VAL A CB  1 
ATOM   157  C  CG1 . VAL A 1 22  ? -6.206  -17.931 24.703  1   45.1   ? 18  VAL A CG1 1 
ATOM   158  C  CG2 . VAL A 1 22  ? -4.254  -17.447 23.204  1   53.48  ? 18  VAL A CG2 1 
ATOM   159  N  N   . TYR A 1 23  ? -5.304  -16.777 27.784  1   49.61  ? 19  TYR A N   1 
ATOM   160  C  CA  . TYR A 1 23  ? -5.363  -17.134 29.218  1   49.82  ? 19  TYR A CA  1 
ATOM   161  C  C   . TYR A 1 23  ? -6.632  -17.884 29.535  1   46.41  ? 19  TYR A C   1 
ATOM   162  O  O   . TYR A 1 23  ? -7.697  -17.52  29.037  1   48.11  ? 19  TYR A O   1 
ATOM   163  C  CB  . TYR A 1 23  ? -5.314  -15.814 29.987  1   55.43  ? 19  TYR A CB  1 
ATOM   164  C  CG  . TYR A 1 23  ? -4.044  -15.518 30.766  1   60.61  ? 19  TYR A CG  1 
ATOM   165  C  CD1 . TYR A 1 23  ? -3.73   -16.224 31.916  1   65.69  ? 19  TYR A CD1 1 
ATOM   166  C  CD2 . TYR A 1 23  ? -3.176  -14.515 30.364  1   62.76  ? 19  TYR A CD2 1 
ATOM   167  C  CE1 . TYR A 1 23  ? -2.583  -15.952 32.64   1   70.18  ? 19  TYR A CE1 1 
ATOM   168  C  CE2 . TYR A 1 23  ? -2.025  -14.231 31.076  1   69.11  ? 19  TYR A CE2 1 
ATOM   169  C  CZ  . TYR A 1 23  ? -1.728  -14.953 32.218  1   70.17  ? 19  TYR A CZ  1 
ATOM   170  O  OH  . TYR A 1 23  ? -0.6    -14.685 32.932  1   70.27  ? 19  TYR A OH  1 
ATOM   171  N  N   . LYS A 1 24  ? -6.514  -18.919 30.356  1   43.95  ? 20  LYS A N   1 
ATOM   172  C  CA  . LYS A 1 24  ? -7.72   -19.623 30.831  1   41.64  ? 20  LYS A CA  1 
ATOM   173  C  C   . LYS A 1 24  ? -8.285  -18.788 31.97   1   42.56  ? 20  LYS A C   1 
ATOM   174  O  O   . LYS A 1 24  ? -7.513  -18.395 32.853  1   46.46  ? 20  LYS A O   1 
ATOM   175  C  CB  . LYS A 1 24  ? -7.418  -21.015 31.388  1   41.14  ? 20  LYS A CB  1 
ATOM   176  C  CG  . LYS A 1 24  ? -8.567  -21.781 32.011  1   40.21  ? 20  LYS A CG  1 
ATOM   177  C  CD  . LYS A 1 24  ? -8.127  -23.199 32.342  1   41.39  ? 20  LYS A CD  1 
ATOM   178  C  CE  . LYS A 1 24  ? -9.048  -23.898 33.281  1   44.79  ? 20  LYS A CE  1 
ATOM   179  N  NZ  . LYS A 1 24  ? -8.973  -25.351 33.125  1   44.14  ? 20  LYS A NZ  1 
ATOM   180  N  N   . ALA A 1 25  ? -9.574  -18.497 31.919  1   39.31  ? 21  ALA A N   1 
ATOM   181  C  CA  . ALA A 1 25  ? -10.168 -17.78  33.038  1   39.74  ? 21  ALA A CA  1 
ATOM   182  C  C   . ALA A 1 25  ? -11.535 -18.371 33.354  1   39.22  ? 21  ALA A C   1 
ATOM   183  O  O   . ALA A 1 25  ? -12.049 -19.211 32.604  1   38.95  ? 21  ALA A O   1 
ATOM   184  C  CB  . ALA A 1 25  ? -10.25  -16.306 32.723  1   40.01  ? 21  ALA A CB  1 
ATOM   185  N  N   . ARG A 1 26  ? -12.118 -17.89  34.446  1   39.22  ? 22  ARG A N   1 
ATOM   186  C  CA  . ARG A 1 26  ? -13.378 -18.379 34.949  1   40.58  ? 22  ARG A CA  1 
ATOM   187  C  C   . ARG A 1 26  ? -14.287 -17.189 35.239  1   42.01  ? 22  ARG A C   1 
ATOM   188  O  O   . ARG A 1 26  ? -13.893 -16.248 35.926  1   43.49  ? 22  ARG A O   1 
ATOM   189  C  CB  . ARG A 1 26  ? -13.024 -19.003 36.298  1   45.85  ? 22  ARG A CB  1 
ATOM   190  C  CG  . ARG A 1 26  ? -14.034 -19.981 36.87   1   50.7   ? 22  ARG A CG  1 
ATOM   191  C  CD  . ARG A 1 26  ? -13.378 -20.686 38.047  1   57.51  ? 22  ARG A CD  1 
ATOM   192  N  NE  . ARG A 1 26  ? -13.769 -19.878 39.209  1   68.55  ? 22  ARG A NE  1 
ATOM   193  C  CZ  . ARG A 1 26  ? -13.006 -19.204 40.076  1   71.7   ? 22  ARG A CZ  1 
ATOM   194  N  NH1 . ARG A 1 26  ? -11.683 -19.267 40.01   1   72.4   ? 22  ARG A NH1 1 
ATOM   195  N  NH2 . ARG A 1 26  ? -13.59  -18.481 41.02   1   66.02  ? 22  ARG A NH2 1 
ATOM   196  N  N   . ASN A 1 27  ? -15.526 -17.256 34.741  1   41.4   ? 23  ASN A N   1 
ATOM   197  C  CA  . ASN A 1 27  ? -16.514 -16.199 35.087  1   40.67  ? 23  ASN A CA  1 
ATOM   198  C  C   . ASN A 1 27  ? -16.99  -16.483 36.512  1   41.68  ? 23  ASN A C   1 
ATOM   199  O  O   . ASN A 1 27  ? -17.652 -17.52  36.709  1   41.63  ? 23  ASN A O   1 
ATOM   200  C  CB  . ASN A 1 27  ? -17.673 -16.152 34.101  1   38.21  ? 23  ASN A CB  1 
ATOM   201  C  CG  . ASN A 1 27  ? -18.617 -15.015 34.405  1   37.64  ? 23  ASN A CG  1 
ATOM   202  O  OD1 . ASN A 1 27  ? -19.656 -15.221 35.043  1   38.19  ? 23  ASN A OD1 1 
ATOM   203  N  ND2 . ASN A 1 27  ? -18.273 -13.813 33.969  1   36.02  ? 23  ASN A ND2 1 
ATOM   204  N  N   . LYS A 1 28  ? -16.684 -15.601 37.465  1   43.65  ? 24  LYS A N   1 
ATOM   205  C  CA  . LYS A 1 28  ? -17.01  -15.88  38.891  1   46.13  ? 24  LYS A CA  1 
ATOM   206  C  C   . LYS A 1 28  ? -18.529 -15.913 39.141  1   46.45  ? 24  LYS A C   1 
ATOM   207  O  O   . LYS A 1 28  ? -18.928 -16.467 40.187  1   47.09  ? 24  LYS A O   1 
ATOM   208  C  CB  . LYS A 1 28  ? -16.329 -14.822 39.766  1   50.22  ? 24  LYS A CB  1 
ATOM   209  C  CG  . LYS A 1 28  ? -14.911 -14.467 39.336  1   54.39  ? 24  LYS A CG  1 
ATOM   210  C  CD  . LYS A 1 28  ? -14.591 -12.985 39.486  1   61.42  ? 24  LYS A CD  1 
ATOM   211  C  CE  . LYS A 1 28  ? -13.14  -12.735 39.741  1   65.48  ? 24  LYS A CE  1 
ATOM   212  N  NZ  . LYS A 1 28  ? -12.633 -11.62  38.939  1   68.12  ? 24  LYS A NZ  1 
ATOM   213  N  N   . LEU A 1 29  ? -19.342 -15.36  38.238  1   45.9   ? 25  LEU A N   1 
ATOM   214  C  CA  . LEU A 1 29  ? -20.806 -15.276 38.496  1   46.31  ? 25  LEU A CA  1 
ATOM   215  C  C   . LEU A 1 29  ? -21.532 -16.512 37.95   1   45.38  ? 25  LEU A C   1 
ATOM   216  O  O   . LEU A 1 29  ? -22.437 -17.009 38.65   1   47.25  ? 25  LEU A O   1 
ATOM   217  C  CB  . LEU A 1 29  ? -21.339 -13.998 37.852  1   45     ? 25  LEU A CB  1 
ATOM   218  C  CG  . LEU A 1 29  ? -21.222 -12.724 38.694  1   45.67  ? 25  LEU A CG  1 
ATOM   219  C  CD1 . LEU A 1 29  ? -21.69  -11.527 37.89   1   45.23  ? 25  LEU A CD1 1 
ATOM   220  C  CD2 . LEU A 1 29  ? -22.025 -12.861 39.976  1   46.29  ? 25  LEU A CD2 1 
ATOM   221  N  N   . THR A 1 30  ? -21.163 -16.983 36.758  1   40.82  ? 26  THR A N   1 
ATOM   222  C  CA  . THR A 1 30  ? -21.852 -18.089 36.123  1   41.62  ? 26  THR A CA  1 
ATOM   223  C  C   . THR A 1 30  ? -21.057 -19.383 36.338  1   43.91  ? 26  THR A C   1 
ATOM   224  O  O   . THR A 1 30  ? -21.615 -20.481 36.272  1   47.05  ? 26  THR A O   1 
ATOM   225  C  CB  . THR A 1 30  ? -22.065 -17.841 34.624  1   39.64  ? 26  THR A CB  1 
ATOM   226  O  OG1 . THR A 1 30  ? -20.793 -17.664 34.016  1   38.12  ? 26  THR A OG1 1 
ATOM   227  C  CG2 . THR A 1 30  ? -22.864 -16.598 34.298  1   40.2   ? 26  THR A CG2 1 
ATOM   228  N  N   . GLY A 1 31  ? -19.742 -19.267 36.566  1   42.78  ? 27  GLY A N   1 
ATOM   229  C  CA  . GLY A 1 31  ? -18.894 -20.438 36.719  1   39.57  ? 27  GLY A CA  1 
ATOM   230  C  C   . GLY A 1 31  ? -18.312 -20.88  35.378  1   37.35  ? 27  GLY A C   1 
ATOM   231  O  O   . GLY A 1 31  ? -17.533 -21.822 35.33   1   36.68  ? 27  GLY A O   1 
ATOM   232  N  N   . GLU A 1 32  ? -18.632 -20.18  34.291  1   35.86  ? 28  GLU A N   1 
ATOM   233  C  CA  . GLU A 1 32  ? -18.164 -20.642 32.993  1   35.72  ? 28  GLU A CA  1 
ATOM   234  C  C   . GLU A 1 32  ? -16.653 -20.444 32.866  1   36.1   ? 28  GLU A C   1 
ATOM   235  O  O   . GLU A 1 32  ? -16.117 -19.427 33.268  1   37.19  ? 28  GLU A O   1 
ATOM   236  C  CB  . GLU A 1 32  ? -18.978 -20.041 31.843  1   35.7   ? 28  GLU A CB  1 
ATOM   237  C  CG  . GLU A 1 32  ? -18.337 -20.265 30.477  1   36.13  ? 28  GLU A CG  1 
ATOM   238  C  CD  . GLU A 1 32  ? -19.181 -19.786 29.299  1   38.36  ? 28  GLU A CD  1 
ATOM   239  O  OE1 . GLU A 1 32  ? -19.782 -18.688 29.435  1   39.51  ? 28  GLU A OE1 1 
ATOM   240  O  OE2 . GLU A 1 32  ? -19.222 -20.479 28.233  1   40.48  ? 28  GLU A OE2 1 
ATOM   241  N  N   . VAL A 1 33  ? -15.969 -21.415 32.269  1   36.43  ? 29  VAL A N   1 
ATOM   242  C  CA  . VAL A 1 33  ? -14.545 -21.301 32.006  1   37.69  ? 29  VAL A CA  1 
ATOM   243  C  C   . VAL A 1 33  ? -14.374 -20.886 30.55   1   38.09  ? 29  VAL A C   1 
ATOM   244  O  O   . VAL A 1 33  ? -14.992 -21.465 29.664  1   37.48  ? 29  VAL A O   1 
ATOM   245  C  CB  . VAL A 1 33  ? -13.872 -22.656 32.277  1   37.68  ? 29  VAL A CB  1 
ATOM   246  C  CG1 . VAL A 1 33  ? -12.414 -22.665 31.864  1   38.85  ? 29  VAL A CG1 1 
ATOM   247  C  CG2 . VAL A 1 33  ? -13.965 -23.033 33.74   1   38.96  ? 29  VAL A CG2 1 
ATOM   248  N  N   . VAL A 1 34  ? -13.533 -19.869 30.326  1   40.62  ? 30  VAL A N   1 
ATOM   249  C  CA  . VAL A 1 34  ? -13.386 -19.213 29.031  1   38.03  ? 30  VAL A CA  1 
ATOM   250  C  C   . VAL A 1 34  ? -11.906 -19.101 28.7    1   37.91  ? 30  VAL A C   1 
ATOM   251  O  O   . VAL A 1 34  ? -11.047 -19.308 29.551  1   39.86  ? 30  VAL A O   1 
ATOM   252  C  CB  . VAL A 1 34  ? -14.011 -17.809 29.089  1   36.6   ? 30  VAL A CB  1 
ATOM   253  C  CG1 . VAL A 1 34  ? -15.515 -17.911 29.273  1   35.67  ? 30  VAL A CG1 1 
ATOM   254  C  CG2 . VAL A 1 34  ? -13.404 -16.949 30.197  1   35.79  ? 30  VAL A CG2 1 
ATOM   255  N  N   . ALA A 1 35  ? -11.626 -18.806 27.443  1   37.23  ? 31  ALA A N   1 
ATOM   256  C  CA  . ALA A 1 35  ? -10.289 -18.385 27.072  1   39.9   ? 31  ALA A CA  1 
ATOM   257  C  C   . ALA A 1 35  ? -10.364 -16.916 26.666  1   41.44  ? 31  ALA A C   1 
ATOM   258  O  O   . ALA A 1 35  ? -11.319 -16.518 25.993  1   40.78  ? 31  ALA A O   1 
ATOM   259  C  CB  . ALA A 1 35  ? -9.743  -19.256 25.954  1   36.07  ? 31  ALA A CB  1 
ATOM   260  N  N   . LEU A 1 36  ? -9.369  -16.141 27.119  1   42.98  ? 32  LEU A N   1 
ATOM   261  C  CA  . LEU A 1 36  ? -9.24   -14.718 26.852  1   43.5   ? 32  LEU A CA  1 
ATOM   262  C  C   . LEU A 1 36  ? -8.045  -14.503 25.936  1   44.09  ? 32  LEU A C   1 
ATOM   263  O  O   . LEU A 1 36  ? -6.957  -14.93  26.275  1   44.76  ? 32  LEU A O   1 
ATOM   264  C  CB  . LEU A 1 36  ? -9.057  -13.999 28.188  1   42.41  ? 32  LEU A CB  1 
ATOM   265  C  CG  . LEU A 1 36  ? -10.153 -14.244 29.241  1   43.58  ? 32  LEU A CG  1 
ATOM   266  C  CD1 . LEU A 1 36  ? -9.883  -13.477 30.525  1   42.82  ? 32  LEU A CD1 1 
ATOM   267  C  CD2 . LEU A 1 36  ? -11.589 -13.965 28.776  1   41.78  ? 32  LEU A CD2 1 
ATOM   268  N  N   . LYS A 1 37  ? -8.273  -13.932 24.745  1   45.58  ? 33  LYS A N   1 
ATOM   269  C  CA  . LYS A 1 37  ? -7.214  -13.32  23.953  1   46.12  ? 33  LYS A CA  1 
ATOM   270  C  C   . LYS A 1 37  ? -7.196  -11.829 24.271  1   47.94  ? 33  LYS A C   1 
ATOM   271  O  O   . LYS A 1 37  ? -8.239  -11.207 24.371  1   51.1   ? 33  LYS A O   1 
ATOM   272  C  CB  . LYS A 1 37  ? -7.371  -13.582 22.451  1   47.17  ? 33  LYS A CB  1 
ATOM   273  C  CG  . LYS A 1 37  ? -7.271  -15.022 21.971  1   45.44  ? 33  LYS A CG  1 
ATOM   274  C  CD  . LYS A 1 37  ? -7.189  -15.144 20.451  1   53.46  ? 33  LYS A CD  1 
ATOM   275  C  CE  . LYS A 1 37  ? -7.133  -16.592 19.951  1   59.06  ? 33  LYS A CE  1 
ATOM   276  N  NZ  . LYS A 1 37  ? -7.045  -16.788 18.492  1   50.89  ? 33  LYS A NZ  1 
ATOM   277  N  N   . LYS A 1 38  ? -6.017  -11.271 24.52   1   52.29  ? 34  LYS A N   1 
ATOM   278  C  CA  . LYS A 1 38  ? -5.904  -9.85   24.818  1   56.62  ? 34  LYS A CA  1 
ATOM   279  C  C   . LYS A 1 38  ? -5.171  -9.203  23.645  1   61.02  ? 34  LYS A C   1 
ATOM   280  O  O   . LYS A 1 38  ? -4.205  -9.781  23.152  1   65.88  ? 34  LYS A O   1 
ATOM   281  C  CB  . LYS A 1 38  ? -5.167  -9.637  26.144  1   57.2   ? 34  LYS A CB  1 
ATOM   282  C  CG  . LYS A 1 38  ? -4.565  -8.265  26.356  1   61.09  ? 34  LYS A CG  1 
ATOM   283  C  CD  . LYS A 1 38  ? -3.488  -8.108  27.427  1   68.91  ? 34  LYS A CD  1 
ATOM   284  C  CE  . LYS A 1 38  ? -3.974  -7.619  28.767  1   73.7   ? 34  LYS A CE  1 
ATOM   285  N  NZ  . LYS A 1 38  ? -2.95   -7.015  29.631  1   75.8   ? 34  LYS A NZ  1 
ATOM   286  N  N   . ILE A 1 39  ? -5.721  -8.09   23.16   1   61.36  ? 35  ILE A N   1 
ATOM   287  C  CA  . ILE A 1 39  ? -5.122  -7.342  22.022  1   64.34  ? 35  ILE A CA  1 
ATOM   288  C  C   . ILE A 1 39  ? -4.857  -5.924  22.53   1   72.95  ? 35  ILE A C   1 
ATOM   289  O  O   . ILE A 1 39  ? -5.829  -5.2    22.789  1   72.84  ? 35  ILE A O   1 
ATOM   290  C  CB  . ILE A 1 39  ? -6.072  -7.335  20.81   1   61.32  ? 35  ILE A CB  1 
ATOM   291  C  CG1 . ILE A 1 39  ? -6.805  -8.662  20.664  1   58.95  ? 35  ILE A CG1 1 
ATOM   292  C  CG2 . ILE A 1 39  ? -5.33   -6.955  19.531  1   59.44  ? 35  ILE A CG2 1 
ATOM   293  C  CD1 . ILE A 1 39  ? -7.557  -8.807  19.358  1   53.35  ? 35  ILE A CD1 1 
ATOM   294  N  N   . ARG A 1 40  ? -3.587  -5.567  22.699  1   89.51  ? 36  ARG A N   1 
ATOM   295  C  CA  . ARG A 1 40  ? -3.232  -4.213  23.194  1   103.81 ? 36  ARG A CA  1 
ATOM   296  C  C   . ARG A 1 40  ? -3.44   -3.221  22.047  1   106.49 ? 36  ARG A C   1 
ATOM   297  O  O   . ARG A 1 40  ? -2.724  -3.321  21.034  1   115.6  ? 36  ARG A O   1 
ATOM   298  C  CB  . ARG A 1 40  ? -1.791  -4.157  23.705  1   106.96 ? 36  ARG A CB  1 
ATOM   299  C  CG  . ARG A 1 40  ? -1.459  -5.229  24.731  1   112.76 ? 36  ARG A CG  1 
ATOM   300  C  CD  . ARG A 1 40  ? -2.309  -5.054  25.973  1   114.89 ? 36  ARG A CD  1 
ATOM   301  N  NE  . ARG A 1 40  ? -1.518  -4.634  27.134  1   117.01 ? 36  ARG A NE  1 
ATOM   302  C  CZ  . ARG A 1 40  ? -1.201  -3.377  27.405  1   115.68 ? 36  ARG A CZ  1 
ATOM   303  N  NH1 . ARG A 1 40  ? -2.113  -2.428  27.295  1   116.68 ? 36  ARG A NH1 1 
ATOM   304  N  NH2 . ARG A 1 40  ? 0.027   -3.074  27.78   1   113.84 ? 36  ARG A NH2 1 
ATOM   305  N  N   . LEU A 1 41  ? -4.402  -2.321  22.2    1   101.87 ? 37  LEU A N   1 
ATOM   306  C  CA  . LEU A 1 41  ? -4.722  -1.389  21.097  1   107.02 ? 37  LEU A CA  1 
ATOM   307  C  C   . LEU A 1 41  ? -3.904  -0.101  21.278  1   110.97 ? 37  LEU A C   1 
ATOM   308  O  O   . LEU A 1 41  ? -2.748  -0.089  20.804  1   114.37 ? 37  LEU A O   1 
ATOM   309  C  CB  . LEU A 1 41  ? -6.227  -1.141  21.14   1   100.78 ? 37  LEU A CB  1 
ATOM   310  C  CG  . LEU A 1 41  ? -7.135  -2.339  20.856  1   81.86  ? 37  LEU A CG  1 
ATOM   311  C  CD1 . LEU A 1 41  ? -8.597  -2.006  21.068  1   75.53  ? 37  LEU A CD1 1 
ATOM   312  C  CD2 . LEU A 1 41  ? -6.887  -2.784  19.428  1   75.94  ? 37  LEU A CD2 1 
ATOM   313  N  N   . THR A 1 45  ? -1.337  0.95    17.445  1   87.87  ? 41  THR A N   1 
ATOM   314  C  CA  . THR A 1 45  ? -0.461  1.913   16.722  1   96.28  ? 41  THR A CA  1 
ATOM   315  C  C   . THR A 1 45  ? -0.957  2.161   15.289  1   92.91  ? 41  THR A C   1 
ATOM   316  O  O   . THR A 1 45  ? -0.742  3.24    14.713  1   89.28  ? 41  THR A O   1 
ATOM   317  C  CB  . THR A 1 45  ? 0.987   1.413   16.752  1   97.24  ? 41  THR A CB  1 
ATOM   318  O  OG1 . THR A 1 45  ? 1.73    2.523   16.244  1   90.88  ? 41  THR A OG1 1 
ATOM   319  C  CG2 . THR A 1 45  ? 1.205   0.102   16.005  1   90.6   ? 41  THR A CG2 1 
ATOM   320  N  N   . GLU A 1 46  ? -1.567  1.115   14.713  1   79.43  ? 42  GLU A N   1 
ATOM   321  C  CA  . GLU A 1 46  ? -2.216  1.15    13.415  1   73.07  ? 42  GLU A CA  1 
ATOM   322  C  C   . GLU A 1 46  ? -3.711  0.9     13.633  1   64.63  ? 42  GLU A C   1 
ATOM   323  O  O   . GLU A 1 46  ? -4.408  0.447   12.729  1   61.48  ? 42  GLU A O   1 
ATOM   324  C  CB  . GLU A 1 46  ? -1.541  0.099   12.516  1   73.08  ? 42  GLU A CB  1 
ATOM   325  C  CG  . GLU A 1 46  ? -1.632  0.343   11.007  1   73.2   ? 42  GLU A CG  1 
ATOM   326  C  CD  . GLU A 1 46  ? -1.06   1.623   10.389  1   81.06  ? 42  GLU A CD  1 
ATOM   327  O  OE1 . GLU A 1 46  ? -1.194  1.736   9.149   1   77.4   ? 42  GLU A OE1 1 
ATOM   328  O  OE2 . GLU A 1 46  ? -0.513  2.521   11.09   1   86.25  ? 42  GLU A OE2 1 
ATOM   329  N  N   . GLY A 1 47  ? -4.188  1.178   14.853  1   61.26  ? 43  GLY A N   1 
ATOM   330  C  CA  . GLY A 1 47  ? -5.573  0.947   15.241  1   56.21  ? 43  GLY A CA  1 
ATOM   331  C  C   . GLY A 1 47  ? -5.862  -0.531  15.459  1   50.81  ? 43  GLY A C   1 
ATOM   332  O  O   . GLY A 1 47  ? -4.944  -1.331  15.585  1   51.6   ? 43  GLY A O   1 
ATOM   333  N  N   . VAL A 1 48  ? -7.14   -0.914  15.497  1   47.09  ? 44  VAL A N   1 
ATOM   334  C  CA  . VAL A 1 48  ? -7.429  -2.328  15.65   1   43.04  ? 44  VAL A CA  1 
ATOM   335  C  C   . VAL A 1 48  ? -6.795  -3.098  14.484  1   43.69  ? 44  VAL A C   1 
ATOM   336  O  O   . VAL A 1 48  ? -6.97   -2.753  13.311  1   44.75  ? 44  VAL A O   1 
ATOM   337  C  CB  . VAL A 1 48  ? -8.936  -2.612  15.756  1   40.31  ? 44  VAL A CB  1 
ATOM   338  C  CG1 . VAL A 1 48  ? -9.232  -4.112  15.874  1   36.14  ? 44  VAL A CG1 1 
ATOM   339  C  CG2 . VAL A 1 48  ? -9.569  -1.786  16.859  1   41.22  ? 44  VAL A CG2 1 
ATOM   340  N  N   . PRO A 1 49  ? -5.996  -4.155  14.747  1   42.47  ? 45  PRO A N   1 
ATOM   341  C  CA  . PRO A 1 49  ? -5.373  -4.911  13.664  1   41.88  ? 45  PRO A CA  1 
ATOM   342  C  C   . PRO A 1 49  ? -6.349  -5.683  12.78   1   41.44  ? 45  PRO A C   1 
ATOM   343  O  O   . PRO A 1 49  ? -7.258  -6.354  13.266  1   42.14  ? 45  PRO A O   1 
ATOM   344  C  CB  . PRO A 1 49  ? -4.428  -5.84   14.431  1   41.07  ? 45  PRO A CB  1 
ATOM   345  C  CG  . PRO A 1 49  ? -5.095  -5.977  15.774  1   40.29  ? 45  PRO A CG  1 
ATOM   346  C  CD  . PRO A 1 49  ? -5.551  -4.585  16.079  1   42.22  ? 45  PRO A CD  1 
ATOM   347  N  N   . SER A 1 50  ? -6.105  -5.639  11.466  1   41.47  ? 46  SER A N   1 
ATOM   348  C  CA  . SER A 1 50  ? -6.981  -6.277  10.497  1   38.89  ? 46  SER A CA  1 
ATOM   349  C  C   . SER A 1 50  ? -7.261  -7.733  10.866  1   37.35  ? 46  SER A C   1 
ATOM   350  O  O   . SER A 1 50  ? -8.36   -8.233  10.609  1   37.62  ? 46  SER A O   1 
ATOM   351  C  CB  . SER A 1 50  ? -6.462  -6.129  9.109   1   38.17  ? 46  SER A CB  1 
ATOM   352  O  OG  . SER A 1 50  ? -5.231  -6.82   9       1   39.4   ? 46  SER A OG  1 
ATOM   353  N  N   A THR A 1 51  ? -6.277  -8.41   11.469  0.5 37.1   ? 47  THR A N   1 
ATOM   354  N  N   B THR A 1 51  ? -6.267  -8.393  11.468  0.5 37.36  ? 47  THR A N   1 
ATOM   355  C  CA  A THR A 1 51  ? -6.451  -9.809  11.846  0.5 35.8   ? 47  THR A CA  1 
ATOM   356  C  CA  B THR A 1 51  ? -6.394  -9.781  11.89   0.5 36.45  ? 47  THR A CA  1 
ATOM   357  C  C   A THR A 1 51  ? -7.605  -9.95   12.835  0.5 34.73  ? 47  THR A C   1 
ATOM   358  C  C   B THR A 1 51  ? -7.594  -9.93   12.819  0.5 35.04  ? 47  THR A C   1 
ATOM   359  O  O   A THR A 1 51  ? -8.4    -10.874 12.721  0.5 33.2   ? 47  THR A O   1 
ATOM   360  O  O   B THR A 1 51  ? -8.39   -10.846 12.66   0.5 33.45  ? 47  THR A O   1 
ATOM   361  C  CB  A THR A 1 51  ? -5.165  -10.449 12.382  0.5 36.53  ? 47  THR A CB  1 
ATOM   362  C  CB  B THR A 1 51  ? -5.123  -10.249 12.6    0.5 37.74  ? 47  THR A CB  1 
ATOM   363  O  OG1 A THR A 1 51  ? -4.556  -9.494  13.25   0.5 37.8   ? 47  THR A OG1 1 
ATOM   364  O  OG1 B THR A 1 51  ? -4.098  -10.224 11.61   0.5 39.93  ? 47  THR A OG1 1 
ATOM   365  C  CG2 A THR A 1 51  ? -4.226  -10.895 11.27   0.5 36.73  ? 47  THR A CG2 1 
ATOM   366  C  CG2 B THR A 1 51  ? -5.294  -11.634 13.199  0.5 35.2   ? 47  THR A CG2 1 
ATOM   367  N  N   . ALA A 1 52  ? -7.693  -9.023  13.795  1   36.75  ? 48  ALA A N   1 
ATOM   368  C  CA  . ALA A 1 52  ? -8.715  -9.091  14.825  1   36.54  ? 48  ALA A CA  1 
ATOM   369  C  C   . ALA A 1 52  ? -10.065 -8.683  14.226  1   38.04  ? 48  ALA A C   1 
ATOM   370  O  O   . ALA A 1 52  ? -11.072 -9.314  14.534  1   35.64  ? 48  ALA A O   1 
ATOM   371  C  CB  . ALA A 1 52  ? -8.319  -8.204  15.978  1   36.2   ? 48  ALA A CB  1 
ATOM   372  N  N   . ILE A 1 53  ? -10.054 -7.631  13.374  1   38.21  ? 49  ILE A N   1 
ATOM   373  C  CA  . ILE A 1 53  ? -11.186 -7.182  12.57   1   39.8   ? 49  ILE A CA  1 
ATOM   374  C  C   . ILE A 1 53  ? -11.835 -8.388  11.867  1   36.81  ? 49  ILE A C   1 
ATOM   375  O  O   . ILE A 1 53  ? -13.062 -8.534  11.85   1   35.56  ? 49  ILE A O   1 
ATOM   376  C  CB  . ILE A 1 53  ? -10.704 -6.128  11.544  1   41.74  ? 49  ILE A CB  1 
ATOM   377  C  CG1 . ILE A 1 53  ? -10.286 -4.806  12.168  1   43.68  ? 49  ILE A CG1 1 
ATOM   378  C  CG2 . ILE A 1 53  ? -11.699 -5.913  10.404  1   41.21  ? 49  ILE A CG2 1 
ATOM   379  C  CD1 . ILE A 1 53  ? -11.443 -4.006  12.701  1   48.7   ? 49  ILE A CD1 1 
ATOM   380  N  N   . ARG A 1 54  ? -11.011 -9.244  11.258  1   34.05  ? 50  ARG A N   1 
ATOM   381  C  CA  . ARG A 1 54  ? -11.556 -10.382 10.544  1   32.5   ? 50  ARG A CA  1 
ATOM   382  C  C   . ARG A 1 54  ? -11.976 -11.466 11.525  1   34.59  ? 50  ARG A C   1 
ATOM   383  O  O   . ARG A 1 54  ? -13.007 -12.104 11.324  1   36.11  ? 50  ARG A O   1 
ATOM   384  C  CB  . ARG A 1 54  ? -10.579 -10.964 9.526   1   29.85  ? 50  ARG A CB  1 
ATOM   385  C  CG  . ARG A 1 54  ? -10.401 -10.031 8.338   1   30.32  ? 50  ARG A CG  1 
ATOM   386  C  CD  . ARG A 1 54  ? -9.388  -10.568 7.363   1   30.45  ? 50  ARG A CD  1 
ATOM   387  N  NE  . ARG A 1 54  ? -9.124  -9.641  6.254   1   31.84  ? 50  ARG A NE  1 
ATOM   388  C  CZ  . ARG A 1 54  ? -8.129  -9.845  5.381   1   32.98  ? 50  ARG A CZ  1 
ATOM   389  N  NH1 . ARG A 1 54  ? -7.249  -10.825 5.571   1   30.98  ? 50  ARG A NH1 1 
ATOM   390  N  NH2 . ARG A 1 54  ? -7.998  -9.066  4.318   1   32.92  ? 50  ARG A NH2 1 
ATOM   391  N  N   . GLU A 1 55  ? -11.171 -11.701 12.567  1   36.34  ? 51  GLU A N   1 
ATOM   392  C  CA  . GLU A 1 55  ? -11.441 -12.838 13.434  1   34.1   ? 51  GLU A CA  1 
ATOM   393  C  C   . GLU A 1 55  ? -12.793 -12.601 14.103  1   32.97  ? 51  GLU A C   1 
ATOM   394  O  O   . GLU A 1 55  ? -13.658 -13.471 14.096  1   30.52  ? 51  GLU A O   1 
ATOM   395  C  CB  . GLU A 1 55  ? -10.308 -12.99  14.447  1   36.03  ? 51  GLU A CB  1 
ATOM   396  C  CG  . GLU A 1 55  ? -10.428 -14.222 15.335  1   37.84  ? 51  GLU A CG  1 
ATOM   397  C  CD  . GLU A 1 55  ? -9.184  -14.457 16.185  1   43.89  ? 51  GLU A CD  1 
ATOM   398  O  OE1 . GLU A 1 55  ? -8.116  -13.819 16.022  1   44.74  ? 51  GLU A OE1 1 
ATOM   399  O  OE2 . GLU A 1 55  ? -9.301  -15.321 17.066  1   46.61  ? 51  GLU A OE2 1 
ATOM   400  N  N   . ILE A 1 56  ? -12.972 -11.398 14.651  1   32.15  ? 52  ILE A N   1 
ATOM   401  C  CA  . ILE A 1 56  ? -14.156 -11.091 15.416  1   32.49  ? 52  ILE A CA  1 
ATOM   402  C  C   . ILE A 1 56  ? -15.341 -11.04  14.455  1   34.56  ? 52  ILE A C   1 
ATOM   403  O  O   . ILE A 1 56  ? -16.374 -11.617 14.769  1   39.01  ? 52  ILE A O   1 
ATOM   404  C  CB  . ILE A 1 56  ? -14.002 -9.783  16.216  1   34     ? 52  ILE A CB  1 
ATOM   405  C  CG1 . ILE A 1 56  ? -12.778 -9.774  17.157  1   32.25  ? 52  ILE A CG1 1 
ATOM   406  C  CG2 . ILE A 1 56  ? -15.309 -9.369  16.925  1   34.77  ? 52  ILE A CG2 1 
ATOM   407  C  CD1 . ILE A 1 56  ? -12.461 -8.379  17.681  1   33.81  ? 52  ILE A CD1 1 
ATOM   408  N  N   . SER A 1 57  ? -15.223 -10.37  13.3    1   34.75  ? 53  SER A N   1 
ATOM   409  C  CA  . SER A 1 57  ? -16.412 -10.178 12.465  1   37.03  ? 53  SER A CA  1 
ATOM   410  C  C   . SER A 1 57  ? -16.88  -11.487 11.808  1   37.25  ? 53  SER A C   1 
ATOM   411  O  O   . SER A 1 57  ? -18.086 -11.697 11.649  1   37.25  ? 53  SER A O   1 
ATOM   412  C  CB  . SER A 1 57  ? -16.283 -9.056  11.466  1   37.77  ? 53  SER A CB  1 
ATOM   413  O  OG  . SER A 1 57  ? -15.41  -9.402  10.395  1   39.25  ? 53  SER A OG  1 
ATOM   414  N  N   . LEU A 1 58  ? -15.932 -12.379 11.474  1   34.9   ? 54  LEU A N   1 
ATOM   415  C  CA  . LEU A 1 58  ? -16.25  -13.677 10.9    1   32.28  ? 54  LEU A CA  1 
ATOM   416  C  C   . LEU A 1 58  ? -16.753 -14.653 11.957  1   34.32  ? 54  LEU A C   1 
ATOM   417  O  O   . LEU A 1 58  ? -17.695 -15.389 11.694  1   37.39  ? 54  LEU A O   1 
ATOM   418  C  CB  . LEU A 1 58  ? -15.058 -14.223 10.135  1   29.36  ? 54  LEU A CB  1 
ATOM   419  C  CG  . LEU A 1 58  ? -14.546 -13.285 9.043   1   29.2   ? 54  LEU A CG  1 
ATOM   420  C  CD1 . LEU A 1 58  ? -13.433 -13.898 8.213   1   27.23  ? 54  LEU A CD1 1 
ATOM   421  C  CD2 . LEU A 1 58  ? -15.699 -12.92  8.184   1   27.86  ? 54  LEU A CD2 1 
ATOM   422  N  N   . LEU A 1 59  ? -16.182 -14.635 13.165  1   36.15  ? 55  LEU A N   1 
ATOM   423  C  CA  . LEU A 1 59  ? -16.631 -15.552 14.205  1   37.09  ? 55  LEU A CA  1 
ATOM   424  C  C   . LEU A 1 59  ? -18.017 -15.191 14.738  1   39.03  ? 55  LEU A C   1 
ATOM   425  O  O   . LEU A 1 59  ? -18.733 -16.066 15.211  1   38.09  ? 55  LEU A O   1 
ATOM   426  C  CB  . LEU A 1 59  ? -15.632 -15.687 15.353  1   36.69  ? 55  LEU A CB  1 
ATOM   427  C  CG  . LEU A 1 59  ? -14.469 -16.634 15.071  1   35.42  ? 55  LEU A CG  1 
ATOM   428  C  CD1 . LEU A 1 59  ? -13.592 -16.701 16.293  1   37.23  ? 55  LEU A CD1 1 
ATOM   429  C  CD2 . LEU A 1 59  ? -14.977 -18.006 14.622  1   32.25  ? 55  LEU A CD2 1 
ATOM   430  N  N   . LYS A 1 60  ? -18.368 -13.902 14.728  1   44.14  ? 56  LYS A N   1 
ATOM   431  C  CA  . LYS A 1 60  ? -19.67  -13.481 15.222  1   49.22  ? 56  LYS A CA  1 
ATOM   432  C  C   . LYS A 1 60  ? -20.783 -14.244 14.498  1   51.64  ? 56  LYS A C   1 
ATOM   433  O  O   . LYS A 1 60  ? -21.718 -14.7   15.162  1   55.96  ? 56  LYS A O   1 
ATOM   434  C  CB  . LYS A 1 60  ? -19.887 -11.966 15.147  1   50.55  ? 56  LYS A CB  1 
ATOM   435  C  CG  . LYS A 1 60  ? -19.305 -11.188 16.303  1   48.55  ? 56  LYS A CG  1 
ATOM   436  C  CD  . LYS A 1 60  ? -19.926 -9.796  16.362  1   54     ? 56  LYS A CD  1 
ATOM   437  C  CE  . LYS A 1 60  ? -21.193 -9.73   17.141  1   57.55  ? 56  LYS A CE  1 
ATOM   438  N  NZ  . LYS A 1 60  ? -21.948 -8.519  16.82   1   65.14  ? 56  LYS A NZ  1 
ATOM   439  N  N   . GLU A 1 61  ? -20.638 -14.406 13.166  1   47.24  ? 57  GLU A N   1 
ATOM   440  C  CA  . GLU A 1 61  ? -21.59  -15.089 12.293  1   50.55  ? 57  GLU A CA  1 
ATOM   441  C  C   . GLU A 1 61  ? -21.469 -16.624 12.274  1   47.29  ? 57  GLU A C   1 
ATOM   442  O  O   . GLU A 1 61  ? -22.39  -17.31  11.837  1   50.91  ? 57  GLU A O   1 
ATOM   443  C  CB  . GLU A 1 61  ? -21.332 -14.698 10.838  1   56.14  ? 57  GLU A CB  1 
ATOM   444  C  CG  . GLU A 1 61  ? -21.778 -13.286 10.475  1   66.66  ? 57  GLU A CG  1 
ATOM   445  C  CD  . GLU A 1 61  ? -21.437 -12.893 9.039   1   78.25  ? 57  GLU A CD  1 
ATOM   446  O  OE1 . GLU A 1 61  ? -21.157 -13.762 8.164   1   77.09  ? 57  GLU A OE1 1 
ATOM   447  O  OE2 . GLU A 1 61  ? -21.435 -11.661 8.799   1   86.53  ? 57  GLU A OE2 1 
ATOM   448  N  N   . LEU A 1 62  ? -20.335 -17.194 12.688  1   39     ? 58  LEU A N   1 
ATOM   449  C  CA  . LEU A 1 62  ? -20.131 -18.62  12.516  1   35.54  ? 58  LEU A CA  1 
ATOM   450  C  C   . LEU A 1 62  ? -20.514 -19.389 13.782  1   35.41  ? 58  LEU A C   1 
ATOM   451  O  O   . LEU A 1 62  ? -19.649 -19.898 14.47   1   39.66  ? 58  LEU A O   1 
ATOM   452  C  CB  . LEU A 1 62  ? -18.658 -18.855 12.171  1   33     ? 58  LEU A CB  1 
ATOM   453  C  CG  . LEU A 1 62  ? -18.151 -18.249 10.855  1   32.36  ? 58  LEU A CG  1 
ATOM   454  C  CD1 . LEU A 1 62  ? -16.721 -18.63  10.647  1   30.33  ? 58  LEU A CD1 1 
ATOM   455  C  CD2 . LEU A 1 62  ? -18.947 -18.7   9.625   1   36.65  ? 58  LEU A CD2 1 
ATOM   456  N  N   A ASN A 1 63  ? -21.806 -19.527 14.049  0.5 35.37  ? 59  ASN A N   1 
ATOM   457  N  N   B ASN A 1 63  ? -21.814 -19.462 14.098  0.5 36.64  ? 59  ASN A N   1 
ATOM   458  C  CA  A ASN A 1 63  ? -22.224 -20.276 15.217  0.5 34.96  ? 59  ASN A CA  1 
ATOM   459  C  CA  B ASN A 1 63  ? -22.303 -20.305 15.184  0.5 37.09  ? 59  ASN A CA  1 
ATOM   460  C  C   A ASN A 1 63  ? -22.503 -21.721 14.801  0.5 31.96  ? 59  ASN A C   1 
ATOM   461  C  C   B ASN A 1 63  ? -22.444 -21.735 14.669  0.5 33.13  ? 59  ASN A C   1 
ATOM   462  O  O   A ASN A 1 63  ? -23.492 -21.999 14.126  0.5 33.93  ? 59  ASN A O   1 
ATOM   463  O  O   B ASN A 1 63  ? -23.283 -22.011 13.811  0.5 35.27  ? 59  ASN A O   1 
ATOM   464  C  CB  A ASN A 1 63  ? -23.296 -19.501 15.983  0.5 38.07  ? 59  ASN A CB  1 
ATOM   465  C  CB  B ASN A 1 63  ? -23.589 -19.781 15.837  0.5 42.06  ? 59  ASN A CB  1 
ATOM   466  C  CG  A ASN A 1 63  ? -22.805 -18.121 16.36   0.5 38.82  ? 59  ASN A CG  1 
ATOM   467  C  CG  B ASN A 1 63  ? -24.161 -20.699 16.903  0.5 45.8   ? 59  ASN A CG  1 
ATOM   468  O  OD1 A ASN A 1 63  ? -23.22  -17.133 15.742  0.5 39.47  ? 59  ASN A OD1 1 
ATOM   469  O  OD1 B ASN A 1 63  ? -25.333 -21.08  16.814  0.5 48.02  ? 59  ASN A OD1 1 
ATOM   470  N  ND2 A ASN A 1 63  ? -21.901 -18.032 17.327  0.5 37.58  ? 59  ASN A ND2 1 
ATOM   471  N  ND2 B ASN A 1 63  ? -23.379 -21.065 17.917  0.5 46.46  ? 59  ASN A ND2 1 
ATOM   472  N  N   . HIS A 1 64  ? -21.603 -22.631 15.191  1   29.28  ? 60  HIS A N   1 
ATOM   473  C  CA  . HIS A 1 64  ? -21.664 -24.034 14.815  1   26.93  ? 60  HIS A CA  1 
ATOM   474  C  C   . HIS A 1 64  ? -20.956 -24.859 15.884  1   28.08  ? 60  HIS A C   1 
ATOM   475  O  O   . HIS A 1 64  ? -20.014 -24.391 16.516  1   28.57  ? 60  HIS A O   1 
ATOM   476  C  CB  . HIS A 1 64  ? -21.003 -24.219 13.448  1   26.27  ? 60  HIS A CB  1 
ATOM   477  C  CG  . HIS A 1 64  ? -21.118 -25.593 12.901  1   28.26  ? 60  HIS A CG  1 
ATOM   478  N  ND1 . HIS A 1 64  ? -20.303 -26.632 13.3    1   27.85  ? 60  HIS A ND1 1 
ATOM   479  C  CD2 . HIS A 1 64  ? -21.978 -26.101 11.984  1   27.07  ? 60  HIS A CD2 1 
ATOM   480  C  CE1 . HIS A 1 64  ? -20.649 -27.726 12.623  1   29.25  ? 60  HIS A CE1 1 
ATOM   481  N  NE2 . HIS A 1 64  ? -21.67  -27.419 11.824  1   28.33  ? 60  HIS A NE2 1 
ATOM   482  N  N   . PRO A 1 65  ? -21.401 -26.094 16.19   1   30.64  ? 61  PRO A N   1 
ATOM   483  C  CA  . PRO A 1 65  ? -20.777 -26.839 17.29   1   28.17  ? 61  PRO A CA  1 
ATOM   484  C  C   . PRO A 1 65  ? -19.329 -27.249 17.044  1   29.59  ? 61  PRO A C   1 
ATOM   485  O  O   . PRO A 1 65  ? -18.675 -27.704 17.969  1   30.65  ? 61  PRO A O   1 
ATOM   486  C  CB  . PRO A 1 65  ? -21.72  -28.05  17.484  1   29.97  ? 61  PRO A CB  1 
ATOM   487  C  CG  . PRO A 1 65  ? -22.481 -28.181 16.164  1   28.89  ? 61  PRO A CG  1 
ATOM   488  C  CD  . PRO A 1 65  ? -22.559 -26.782 15.576  1   29.48  ? 61  PRO A CD  1 
ATOM   489  N  N   . ASN A 1 66  ? -18.831 -27.092 15.803  1   28.4   ? 62  ASN A N   1 
ATOM   490  C  CA  . ASN A 1 66  ? -17.473 -27.478 15.456  1   26.08  ? 62  ASN A CA  1 
ATOM   491  C  C   . ASN A 1 66  ? -16.648 -26.258 15.043  1   26.94  ? 62  ASN A C   1 
ATOM   492  O  O   . ASN A 1 66  ? -15.596 -26.402 14.416  1   26.46  ? 62  ASN A O   1 
ATOM   493  C  CB  . ASN A 1 66  ? -17.449 -28.573 14.397  1   24.94  ? 62  ASN A CB  1 
ATOM   494  C  CG  . ASN A 1 66  ? -18.198 -29.786 14.889  1   28.49  ? 62  ASN A CG  1 
ATOM   495  O  OD1 . ASN A 1 66  ? -19.258 -30.119 14.335  1   31.39  ? 62  ASN A OD1 1 
ATOM   496  N  ND2 . ASN A 1 66  ? -17.666 -30.457 15.912  1   25.82  ? 62  ASN A ND2 1 
ATOM   497  N  N   . ILE A 1 67  ? -17.11  -25.064 15.437  1   27.01  ? 63  ILE A N   1 
ATOM   498  C  CA  . ILE A 1 67  ? -16.282 -23.866 15.431  1   27.51  ? 63  ILE A CA  1 
ATOM   499  C  C   . ILE A 1 67  ? -16.285 -23.264 16.84   1   29.72  ? 63  ILE A C   1 
ATOM   500  O  O   . ILE A 1 67  ? -17.353 -23.14  17.445  1   31.39  ? 63  ILE A O   1 
ATOM   501  C  CB  . ILE A 1 67  ? -16.884 -22.909 14.386  1   26.82  ? 63  ILE A CB  1 
ATOM   502  C  CG1 . ILE A 1 67  ? -16.993 -23.599 13.008  1   28.11  ? 63  ILE A CG1 1 
ATOM   503  C  CG2 . ILE A 1 67  ? -16.124 -21.592 14.334  1   25.79  ? 63  ILE A CG2 1 
ATOM   504  C  CD1 . ILE A 1 67  ? -17.792 -22.845 11.956  1   28.46  ? 63  ILE A CD1 1 
ATOM   505  N  N   A VAL A 1 68  ? -15.112 -22.881 17.363  0.5 30.15  ? 64  VAL A N   1 
ATOM   506  N  N   B VAL A 1 68  ? -15.098 -22.888 17.346  0.5 30.37  ? 64  VAL A N   1 
ATOM   507  C  CA  A VAL A 1 68  ? -15.028 -22.326 18.71   0.5 30.18  ? 64  VAL A CA  1 
ATOM   508  C  CA  B VAL A 1 68  ? -14.966 -22.155 18.601  0.5 30.82  ? 64  VAL A CA  1 
ATOM   509  C  C   A VAL A 1 68  ? -15.858 -21.053 18.791  0.5 31.05  ? 64  VAL A C   1 
ATOM   510  C  C   B VAL A 1 68  ? -16.038 -21.081 18.67   0.5 31.64  ? 64  VAL A C   1 
ATOM   511  O  O   A VAL A 1 68  ? -15.731 -20.187 17.932  0.5 31.2   ? 64  VAL A O   1 
ATOM   512  O  O   B VAL A 1 68  ? -16.244 -20.368 17.688  0.5 31.84  ? 64  VAL A O   1 
ATOM   513  C  CB  A VAL A 1 68  ? -13.58  -22.039 19.127  0.5 30.15  ? 64  VAL A CB  1 
ATOM   514  C  CB  B VAL A 1 68  ? -13.603 -21.464 18.767  0.5 30.92  ? 64  VAL A CB  1 
ATOM   515  C  CG1 A VAL A 1 68  ? -13.468 -21.715 20.613  0.5 28.09  ? 64  VAL A CG1 1 
ATOM   516  C  CG1 B VAL A 1 68  ? -12.523 -22.454 19.163  0.5 34.29  ? 64  VAL A CG1 1 
ATOM   517  C  CG2 A VAL A 1 68  ? -12.695 -23.219 18.769  0.5 31.34  ? 64  VAL A CG2 1 
ATOM   518  C  CG2 B VAL A 1 68  ? -13.217 -20.64  17.544  0.5 28.17  ? 64  VAL A CG2 1 
ATOM   519  N  N   . LYS A 1 69  ? -16.689 -20.969 19.837  1   33.13  ? 65  LYS A N   1 
ATOM   520  C  CA  . LYS A 1 69  ? -17.612 -19.873 20.067  1   35.24  ? 65  LYS A CA  1 
ATOM   521  C  C   . LYS A 1 69  ? -16.827 -18.709 20.633  1   36.01  ? 65  LYS A C   1 
ATOM   522  O  O   . LYS A 1 69  ? -16.191 -18.869 21.68   1   38.64  ? 65  LYS A O   1 
ATOM   523  C  CB  . LYS A 1 69  ? -18.71  -20.188 21.082  1   40.46  ? 65  LYS A CB  1 
ATOM   524  C  CG  . LYS A 1 69  ? -19.971 -20.799 20.497  1   54.16  ? 65  LYS A CG  1 
ATOM   525  C  CD  . LYS A 1 69  ? -20.835 -21.638 21.444  1   67.01  ? 65  LYS A CD  1 
ATOM   526  C  CE  . LYS A 1 69  ? -21.403 -22.912 20.831  1   71.99  ? 65  LYS A CE  1 
ATOM   527  N  NZ  . LYS A 1 69  ? -22.091 -23.777 21.8    1   73.93  ? 65  LYS A NZ  1 
ATOM   528  N  N   . LEU A 1 70  ? -16.841 -17.601 19.875  1   33.4   ? 66  LEU A N   1 
ATOM   529  C  CA  . LEU A 1 70  ? -16.61  -16.259 20.377  1   33.27  ? 66  LEU A CA  1 
ATOM   530  C  C   . LEU A 1 70  ? -17.809 -15.873 21.226  1   35.58  ? 66  LEU A C   1 
ATOM   531  O  O   . LEU A 1 70  ? -18.894 -15.698 20.689  1   37.59  ? 66  LEU A O   1 
ATOM   532  C  CB  . LEU A 1 70  ? -16.498 -15.278 19.215  1   31.09  ? 66  LEU A CB  1 
ATOM   533  C  CG  . LEU A 1 70  ? -16.039 -13.861 19.582  1   30.83  ? 66  LEU A CG  1 
ATOM   534  C  CD1 . LEU A 1 70  ? -14.779 -13.843 20.46   1   31.49  ? 66  LEU A CD1 1 
ATOM   535  C  CD2 . LEU A 1 70  ? -15.815 -13.105 18.307  1   30.74  ? 66  LEU A CD2 1 
ATOM   536  N  N   . LEU A 1 71  ? -17.584 -15.718 22.533  1   36.46  ? 67  LEU A N   1 
ATOM   537  C  CA  . LEU A 1 71  ? -18.648 -15.488 23.492  1   37.65  ? 67  LEU A CA  1 
ATOM   538  C  C   . LEU A 1 71  ? -18.969 -14.006 23.602  1   37.93  ? 67  LEU A C   1 
ATOM   539  O  O   . LEU A 1 71  ? -20.127 -13.656 23.793  1   40.14  ? 67  LEU A O   1 
ATOM   540  C  CB  . LEU A 1 71  ? -18.296 -16.063 24.861  1   39.31  ? 67  LEU A CB  1 
ATOM   541  C  CG  . LEU A 1 71  ? -18.151 -17.586 24.907  1   40.92  ? 67  LEU A CG  1 
ATOM   542  C  CD1 . LEU A 1 71  ? -17.7   -18.1   26.284  1   40     ? 67  LEU A CD1 1 
ATOM   543  C  CD2 . LEU A 1 71  ? -19.484 -18.2   24.494  1   39.07  ? 67  LEU A CD2 1 
ATOM   544  N  N   . ASP A 1 72  ? -17.934 -13.17  23.516  1   36.07  ? 68  ASP A N   1 
ATOM   545  C  CA  . ASP A 1 72  ? -18.046 -11.767 23.837  1   36.98  ? 68  ASP A CA  1 
ATOM   546  C  C   . ASP A 1 72  ? -16.797 -11.054 23.34   1   37.15  ? 68  ASP A C   1 
ATOM   547  O  O   . ASP A 1 72  ? -15.796 -11.704 23.076  1   36.96  ? 68  ASP A O   1 
ATOM   548  C  CB  . ASP A 1 72  ? -18.212 -11.531 25.331  1   38.66  ? 68  ASP A CB  1 
ATOM   549  C  CG  . ASP A 1 72  ? -18.868 -10.196 25.673  1   42.67  ? 68  ASP A CG  1 
ATOM   550  O  OD1 . ASP A 1 72  ? -19.069 -9.357  24.756  1   42.86  ? 68  ASP A OD1 1 
ATOM   551  O  OD2 . ASP A 1 72  ? -19.177 -9.992  26.851  1   45.52  ? 68  ASP A OD2 1 
ATOM   552  N  N   . VAL A 1 73  ? -16.882 -9.724  23.211  1   36.31  ? 69  VAL A N   1 
ATOM   553  C  CA  . VAL A 1 73  ? -15.725 -8.888  22.989  1   36.6   ? 69  VAL A CA  1 
ATOM   554  C  C   . VAL A 1 73  ? -15.835 -7.737  23.97   1   40.65  ? 69  VAL A C   1 
ATOM   555  O  O   . VAL A 1 73  ? -16.831 -7.024  23.925  1   42.23  ? 69  VAL A O   1 
ATOM   556  C  CB  . VAL A 1 73  ? -15.704 -8.325  21.561  1   36.14  ? 69  VAL A CB  1 
ATOM   557  C  CG1 . VAL A 1 73  ? -14.685 -7.192  21.469  1   36.12  ? 69  VAL A CG1 1 
ATOM   558  C  CG2 . VAL A 1 73  ? -15.47  -9.423  20.514  1   32.75  ? 69  VAL A CG2 1 
ATOM   559  N  N   . ILE A 1 74  ? -14.832 -7.57   24.847  1   43.08  ? 70  ILE A N   1 
ATOM   560  C  CA  . ILE A 1 74  ? -14.889 -6.541  25.871  1   45.89  ? 70  ILE A CA  1 
ATOM   561  C  C   . ILE A 1 74  ? -13.888 -5.456  25.511  1   50.44  ? 70  ILE A C   1 
ATOM   562  O  O   . ILE A 1 74  ? -12.73  -5.78   25.292  1   51     ? 70  ILE A O   1 
ATOM   563  C  CB  . ILE A 1 74  ? -14.627 -7.16   27.248  1   45.71  ? 70  ILE A CB  1 
ATOM   564  C  CG1 . ILE A 1 74  ? -15.639 -8.286  27.515  1   43.41  ? 70  ILE A CG1 1 
ATOM   565  C  CG2 . ILE A 1 74  ? -14.686 -6.07   28.321  1   47.94  ? 70  ILE A CG2 1 
ATOM   566  C  CD1 . ILE A 1 74  ? -15.32  -9.217  28.669  1   42.88  ? 70  ILE A CD1 1 
ATOM   567  N  N   . HIS A 1 75  ? -14.357 -4.216  25.396  1   58.87  ? 71  HIS A N   1 
ATOM   568  C  CA  . HIS A 1 75  ? -13.474 -3.068  25.065  1   69.29  ? 71  HIS A CA  1 
ATOM   569  C  C   . HIS A 1 75  ? -13.197 -2.251  26.324  1   72.11  ? 71  HIS A C   1 
ATOM   570  O  O   . HIS A 1 75  ? -14.004 -1.374  26.667  1   74.07  ? 71  HIS A O   1 
ATOM   571  C  CB  . HIS A 1 75  ? -14.124 -2.097  24.078  1   75.58  ? 71  HIS A CB  1 
ATOM   572  C  CG  . HIS A 1 75  ? -14.915 -2.683  22.956  1   83.97  ? 71  HIS A CG  1 
ATOM   573  N  ND1 . HIS A 1 75  ? -16.091 -3.38   23.127  1   83.77  ? 71  HIS A ND1 1 
ATOM   574  C  CD2 . HIS A 1 75  ? -14.716 -2.619  21.635  1   88.76  ? 71  HIS A CD2 1 
ATOM   575  C  CE1 . HIS A 1 75  ? -16.558 -3.745  21.944  1   86.85  ? 71  HIS A CE1 1 
ATOM   576  N  NE2 . HIS A 1 75  ? -15.739 -3.291  21.023  1   85.96  ? 71  HIS A NE2 1 
ATOM   577  N  N   . THR A 1 76  ? -12.08  -2.526  26.987  1   76.79  ? 72  THR A N   1 
ATOM   578  C  CA  . THR A 1 76  ? -11.717 -1.755  28.184  1   83.45  ? 72  THR A CA  1 
ATOM   579  C  C   . THR A 1 76  ? -10.859 -0.593  27.753  1   96.68  ? 72  THR A C   1 
ATOM   580  O  O   . THR A 1 76  ? -11.105 -0.054  26.655  1   100.58 ? 72  THR A O   1 
ATOM   581  C  CB  . THR A 1 76  ? -11.026 -2.668  29.193  1   80.57  ? 72  THR A CB  1 
ATOM   582  O  OG1 . THR A 1 76  ? -10.67  -1.851  30.303  1   87.24  ? 72  THR A OG1 1 
ATOM   583  C  CG2 . THR A 1 76  ? -9.795  -3.342  28.62   1   82.67  ? 72  THR A CG2 1 
ATOM   584  N  N   . GLU A 1 77  ? -9.886  -0.205  28.572  1   108.31 ? 73  GLU A N   1 
ATOM   585  C  CA  . GLU A 1 77  ? -9.064  0.99    28.26   1   111.56 ? 73  GLU A CA  1 
ATOM   586  C  C   . GLU A 1 77  ? -7.829  0.597   27.435  1   108    ? 73  GLU A C   1 
ATOM   587  O  O   . GLU A 1 77  ? -7.004  -0.179  27.954  1   114.65 ? 73  GLU A O   1 
ATOM   588  C  CB  . GLU A 1 77  ? -8.686  1.641   29.585  1   121.58 ? 73  GLU A CB  1 
ATOM   589  C  CG  . GLU A 1 77  ? -9.858  1.74    30.557  1   134.94 ? 73  GLU A CG  1 
ATOM   590  C  CD  . GLU A 1 77  ? -11.122 2.333   29.963  1   138.84 ? 73  GLU A CD  1 
ATOM   591  O  OE1 . GLU A 1 77  ? -11.081 3.495   29.509  1   135.93 ? 73  GLU A OE1 1 
ATOM   592  O  OE2 . GLU A 1 77  ? -12.15  1.625   29.955  1   139.33 ? 73  GLU A OE2 1 
ATOM   593  N  N   . ASN A 1 78  ? -7.712  1.123   26.214  1   94.89  ? 74  ASN A N   1 
ATOM   594  C  CA  . ASN A 1 78  ? -6.518  0.856   25.361  1   89.68  ? 74  ASN A CA  1 
ATOM   595  C  C   . ASN A 1 78  ? -6.36   -0.649  25.153  1   82.63  ? 74  ASN A C   1 
ATOM   596  O  O   . ASN A 1 78  ? -5.276  -1.075  24.724  1   82.13  ? 74  ASN A O   1 
ATOM   597  C  CB  . ASN A 1 78  ? -5.264  1.492   25.951  1   94.38  ? 74  ASN A CB  1 
ATOM   598  C  CG  . ASN A 1 78  ? -5.55   2.794   26.659  1   100.06 ? 74  ASN A CG  1 
ATOM   599  O  OD1 . ASN A 1 78  ? -5.451  2.867   27.888  1   101.24 ? 74  ASN A OD1 1 
ATOM   600  N  ND2 . ASN A 1 78  ? -5.906  3.827   25.91   1   103.22 ? 74  ASN A ND2 1 
ATOM   601  N  N   . LYS A 1 79  ? -7.416  -1.416  25.41   1   76.78  ? 75  LYS A N   1 
ATOM   602  C  CA  . LYS A 1 79  ? -7.313  -2.866  25.329  1   68.36  ? 75  LYS A CA  1 
ATOM   603  C  C   . LYS A 1 79  ? -8.61   -3.486  24.816  1   61.22  ? 75  LYS A C   1 
ATOM   604  O  O   . LYS A 1 79  ? -9.699  -3.005  25.119  1   60.64  ? 75  LYS A O   1 
ATOM   605  C  CB  . LYS A 1 79  ? -7.014  -3.416  26.728  1   71.14  ? 75  LYS A CB  1 
ATOM   606  C  CG  . LYS A 1 79  ? -5.533  -3.503  27.024  1   74.58  ? 75  LYS A CG  1 
ATOM   607  C  CD  . LYS A 1 79  ? -5.13   -4.126  28.353  1   77.57  ? 75  LYS A CD  1 
ATOM   608  C  CE  . LYS A 1 79  ? -5.272  -3.228  29.545  1   84.09  ? 75  LYS A CE  1 
ATOM   609  N  NZ  . LYS A 1 79  ? -4.248  -3.655  30.501  1   86.35  ? 75  LYS A NZ  1 
ATOM   610  N  N   . LEU A 1 80  ? -8.475  -4.591  24.078  1   55.24  ? 76  LEU A N   1 
ATOM   611  C  CA  . LEU A 1 80  ? -9.609  -5.361  23.602  1   52.55  ? 76  LEU A CA  1 
ATOM   612  C  C   . LEU A 1 80  ? -9.453  -6.841  23.986  1   53.17  ? 76  LEU A C   1 
ATOM   613  O  O   . LEU A 1 80  ? -8.415  -7.457  23.716  1   49.49  ? 76  LEU A O   1 
ATOM   614  C  CB  . LEU A 1 80  ? -9.561  -5.152  22.094  1   52.06  ? 76  LEU A CB  1 
ATOM   615  C  CG  . LEU A 1 80  ? -10.75  -5.675  21.29   1   50.25  ? 76  LEU A CG  1 
ATOM   616  C  CD1 . LEU A 1 80  ? -11.841 -4.634  21.484  1   52.31  ? 76  LEU A CD1 1 
ATOM   617  C  CD2 . LEU A 1 80  ? -10.282 -5.74   19.847  1   47.8   ? 76  LEU A CD2 1 
ATOM   618  N  N   . TYR A 1 81  ? -10.503 -7.418  24.602  1   51.44  ? 77  TYR A N   1 
ATOM   619  C  CA  . TYR A 1 81  ? -10.481 -8.803  25.05   1   48.39  ? 77  TYR A CA  1 
ATOM   620  C  C   . TYR A 1 81  ? -11.515 -9.618  24.287  1   46.22  ? 77  TYR A C   1 
ATOM   621  O  O   . TYR A 1 81  ? -12.682 -9.245  24.209  1   45.42  ? 77  TYR A O   1 
ATOM   622  C  CB  . TYR A 1 81  ? -10.801 -8.949  26.54   1   51.59  ? 77  TYR A CB  1 
ATOM   623  C  CG  . TYR A 1 81  ? -9.747  -8.396  27.492  1   54.93  ? 77  TYR A CG  1 
ATOM   624  C  CD1 . TYR A 1 81  ? -8.668  -9.178  27.912  1   56     ? 77  TYR A CD1 1 
ATOM   625  C  CD2 . TYR A 1 81  ? -9.831  -7.093  27.969  1   55.22  ? 77  TYR A CD2 1 
ATOM   626  C  CE1 . TYR A 1 81  ? -7.702  -8.677  28.776  1   57.61  ? 77  TYR A CE1 1 
ATOM   627  C  CE2 . TYR A 1 81  ? -8.88   -6.588  28.842  1   58.7   ? 77  TYR A CE2 1 
ATOM   628  C  CZ  . TYR A 1 81  ? -7.81   -7.375  29.242  1   60.14  ? 77  TYR A CZ  1 
ATOM   629  O  OH  . TYR A 1 81  ? -6.882  -6.85   30.109  1   66.03  ? 77  TYR A OH  1 
ATOM   630  N  N   . LEU A 1 82  ? -11.047 -10.742 23.747  1   43.84  ? 78  LEU A N   1 
ATOM   631  C  CA  . LEU A 1 82  ? -11.888 -11.735 23.113  1   43.58  ? 78  LEU A CA  1 
ATOM   632  C  C   . LEU A 1 82  ? -12.126 -12.861 24.109  1   41.82  ? 78  LEU A C   1 
ATOM   633  O  O   . LEU A 1 82  ? -11.167 -13.466 24.569  1   43.58  ? 78  LEU A O   1 
ATOM   634  C  CB  . LEU A 1 82  ? -11.199 -12.283 21.86   1   41.64  ? 78  LEU A CB  1 
ATOM   635  C  CG  . LEU A 1 82  ? -11.292 -11.393 20.617  1   43.65  ? 78  LEU A CG  1 
ATOM   636  C  CD1 . LEU A 1 82  ? -10.735 -10.003 20.864  1   42.53  ? 78  LEU A CD1 1 
ATOM   637  C  CD2 . LEU A 1 82  ? -10.616 -12.055 19.433  1   41.24  ? 78  LEU A CD2 1 
ATOM   638  N  N   . VAL A 1 83  ? -13.396 -13.176 24.368  1   38.76  ? 79  VAL A N   1 
ATOM   639  C  CA  . VAL A 1 83  ? -13.763 -14.254 25.269  1   37.02  ? 79  VAL A CA  1 
ATOM   640  C  C   . VAL A 1 83  ? -14.238 -15.455 24.451  1   36.69  ? 79  VAL A C   1 
ATOM   641  O  O   . VAL A 1 83  ? -15.303 -15.409 23.832  1   37.17  ? 79  VAL A O   1 
ATOM   642  C  CB  . VAL A 1 83  ? -14.831 -13.769 26.266  1   36.89  ? 79  VAL A CB  1 
ATOM   643  C  CG1 . VAL A 1 83  ? -15.154 -14.823 27.323  1   34.55  ? 79  VAL A CG1 1 
ATOM   644  C  CG2 . VAL A 1 83  ? -14.444 -12.432 26.9    1   37.59  ? 79  VAL A CG2 1 
ATOM   645  N  N   . PHE A 1 84  ? -13.452 -16.546 24.441  1   33.93  ? 80  PHE A N   1 
ATOM   646  C  CA  . PHE A 1 84  ? -13.901 -17.738 23.744  1   32.54  ? 80  PHE A CA  1 
ATOM   647  C  C   . PHE A 1 84  ? -14.351 -18.822 24.725  1   35.32  ? 80  PHE A C   1 
ATOM   648  O  O   . PHE A 1 84  ? -14.002 -18.773 25.916  1   38.31  ? 80  PHE A O   1 
ATOM   649  C  CB  . PHE A 1 84  ? -12.699 -18.279 22.988  1   29.86  ? 80  PHE A CB  1 
ATOM   650  C  CG  . PHE A 1 84  ? -12.174 -17.4   21.876  1   30.93  ? 80  PHE A CG  1 
ATOM   651  C  CD1 . PHE A 1 84  ? -11.207 -16.429 22.14   1   34.59  ? 80  PHE A CD1 1 
ATOM   652  C  CD2 . PHE A 1 84  ? -12.616 -17.569 20.559  1   28.5   ? 80  PHE A CD2 1 
ATOM   653  C  CE1 . PHE A 1 84  ? -10.702 -15.662 21.082  1   35.58  ? 80  PHE A CE1 1 
ATOM   654  C  CE2 . PHE A 1 84  ? -12.099 -16.81  19.517  1   27.6   ? 80  PHE A CE2 1 
ATOM   655  C  CZ  . PHE A 1 84  ? -11.155 -15.855 19.776  1   30.94  ? 80  PHE A CZ  1 
ATOM   656  N  N   . GLU A 1 85  ? -15.1   -19.822 24.218  1   33.9   ? 81  GLU A N   1 
ATOM   657  C  CA  . GLU A 1 85  ? -15.355 -21.001 25.031  1   35.02  ? 81  GLU A CA  1 
ATOM   658  C  C   . GLU A 1 85  ? -14.016 -21.718 25.262  1   36.57  ? 81  GLU A C   1 
ATOM   659  O  O   . GLU A 1 85  ? -13.131 -21.682 24.403  1   34.73  ? 81  GLU A O   1 
ATOM   660  C  CB  . GLU A 1 85  ? -16.39  -21.926 24.399  1   33.1   ? 81  GLU A CB  1 
ATOM   661  C  CG  . GLU A 1 85  ? -15.844 -22.593 23.146  1   33.98  ? 81  GLU A CG  1 
ATOM   662  C  CD  . GLU A 1 85  ? -16.72  -23.628 22.463  1   35.86  ? 81  GLU A CD  1 
ATOM   663  O  OE1 . GLU A 1 85  ? -17.252 -24.544 23.137  1   37.16  ? 81  GLU A OE1 1 
ATOM   664  O  OE2 . GLU A 1 85  ? -16.807 -23.547 21.22   1   37.4   ? 81  GLU A OE2 1 
ATOM   665  N  N   . PHE A 1 86  ? -13.839 -22.317 26.452  1   37.09  ? 82  PHE A N   1 
ATOM   666  C  CA  . PHE A 1 86  ? -12.636 -23.076 26.768  1   35.59  ? 82  PHE A CA  1 
ATOM   667  C  C   . PHE A 1 86  ? -12.715 -24.52  26.259  1   34.56  ? 82  PHE A C   1 
ATOM   668  O  O   . PHE A 1 86  ? -13.713 -25.2   26.471  1   37.09  ? 82  PHE A O   1 
ATOM   669  C  CB  . PHE A 1 86  ? -12.363 -22.946 28.26   1   36.43  ? 82  PHE A CB  1 
ATOM   670  C  CG  . PHE A 1 86  ? -11.226 -23.854 28.693  1   38.98  ? 82  PHE A CG  1 
ATOM   671  C  CD1 . PHE A 1 86  ? -9.912  -23.453 28.523  1   39.08  ? 82  PHE A CD1 1 
ATOM   672  C  CD2 . PHE A 1 86  ? -11.464 -25.124 29.223  1   39.17  ? 82  PHE A CD2 1 
ATOM   673  C  CE1 . PHE A 1 86  ? -8.864  -24.27  28.919  1   39.96  ? 82  PHE A CE1 1 
ATOM   674  C  CE2 . PHE A 1 86  ? -10.411 -25.938 29.616  1   40.58  ? 82  PHE A CE2 1 
ATOM   675  C  CZ  . PHE A 1 86  ? -9.118  -25.512 29.45   1   41.11  ? 82  PHE A CZ  1 
ATOM   676  N  N   . LEU A 1 87  ? -11.652 -24.96  25.569  1   34.29  ? 83  LEU A N   1 
ATOM   677  C  CA  . LEU A 1 87  ? -11.379 -26.331 25.166  1   35.07  ? 83  LEU A CA  1 
ATOM   678  C  C   . LEU A 1 87  ? -10.053 -26.737 25.823  1   35.69  ? 83  LEU A C   1 
ATOM   679  O  O   . LEU A 1 87  ? -9.101  -25.97  25.799  1   36.22  ? 83  LEU A O   1 
ATOM   680  C  CB  . LEU A 1 87  ? -11.294 -26.352 23.637  1   38.15  ? 83  LEU A CB  1 
ATOM   681  C  CG  . LEU A 1 87  ? -12.563 -26.208 22.765  1   37.5   ? 83  LEU A CG  1 
ATOM   682  C  CD1 . LEU A 1 87  ? -13.505 -27.377 22.766  1   41.73  ? 83  LEU A CD1 1 
ATOM   683  C  CD2 . LEU A 1 87  ? -13.365 -24.953 22.855  1   34.07  ? 83  LEU A CD2 1 
ATOM   684  N  N   A HIS A 1 88  ? -10.041 -27.906 26.467  0.5 36.65  ? 84  HIS A N   1 
ATOM   685  N  N   B HIS A 1 88  ? -10.031 -27.915 26.466  0.5 38.56  ? 84  HIS A N   1 
ATOM   686  C  CA  A HIS A 1 88  ? -8.903  -28.39  27.237  0.5 38.36  ? 84  HIS A CA  1 
ATOM   687  C  CA  B HIS A 1 88  ? -8.872  -28.352 27.238  0.5 41.87  ? 84  HIS A CA  1 
ATOM   688  C  C   A HIS A 1 88  ? -7.616  -28.44  26.407  0.5 39.3   ? 84  HIS A C   1 
ATOM   689  C  C   B HIS A 1 88  ? -7.598  -28.422 26.396  0.5 41.39  ? 84  HIS A C   1 
ATOM   690  O  O   A HIS A 1 88  ? -6.643  -27.825 26.806  0.5 41.82  ? 84  HIS A O   1 
ATOM   691  O  O   B HIS A 1 88  ? -6.618  -27.808 26.778  0.5 44.13  ? 84  HIS A O   1 
ATOM   692  C  CB  A HIS A 1 88  ? -9.266  -29.687 27.962  0.5 35.57  ? 84  HIS A CB  1 
ATOM   693  C  CB  B HIS A 1 88  ? -9.121  -29.595 28.105  0.5 42.13  ? 84  HIS A CB  1 
ATOM   694  C  CG  A HIS A 1 88  ? -10.627 -29.649 28.573  0.5 33.72  ? 84  HIS A CG  1 
ATOM   695  C  CG  B HIS A 1 88  ? -9.033  -30.924 27.415  0.5 41.9   ? 84  HIS A CG  1 
ATOM   696  N  ND1 A HIS A 1 88  ? -11.773 -29.851 27.827  0.5 30.53  ? 84  HIS A ND1 1 
ATOM   697  N  ND1 B HIS A 1 88  ? -9.86   -31.272 26.365  0.5 42.18  ? 84  HIS A ND1 1 
ATOM   698  C  CD2 A HIS A 1 88  ? -11.02  -29.436 29.845  0.5 33.25  ? 84  HIS A CD2 1 
ATOM   699  C  CD2 B HIS A 1 88  ? -8.278  -32.02  27.669  0.5 42.37  ? 84  HIS A CD2 1 
ATOM   700  C  CE1 A HIS A 1 88  ? -12.82  -29.8   28.622  0.5 31.01  ? 84  HIS A CE1 1 
ATOM   701  C  CE1 B HIS A 1 88  ? -9.59   -32.522 25.98   0.5 41.61  ? 84  HIS A CE1 1 
ATOM   702  N  NE2 A HIS A 1 88  ? -12.388 -29.537 29.85   0.5 32.74  ? 84  HIS A NE2 1 
ATOM   703  N  NE2 B HIS A 1 88  ? -8.643  -33.005 26.775  0.5 41.23  ? 84  HIS A NE2 1 
ATOM   704  N  N   . GLN A 1 89  ? -7.595  -29.162 25.297  1   38.78  ? 85  GLN A N   1 
ATOM   705  C  CA  . GLN A 1 89  ? -6.33   -29.421 24.639  1   41.63  ? 85  GLN A CA  1 
ATOM   706  C  C   . GLN A 1 89  ? -6.518  -29.038 23.174  1   39.59  ? 85  GLN A C   1 
ATOM   707  O  O   . GLN A 1 89  ? -7.642  -28.89  22.711  1   37.39  ? 85  GLN A O   1 
ATOM   708  C  CB  . GLN A 1 89  ? -6.07   -30.918 24.866  1   49.4   ? 85  GLN A CB  1 
ATOM   709  C  CG  . GLN A 1 89  ? -4.607  -31.348 24.846  1   59.81  ? 85  GLN A CG  1 
ATOM   710  C  CD  . GLN A 1 89  ? -4.398  -32.856 24.872  1   73     ? 85  GLN A CD  1 
ATOM   711  O  OE1 . GLN A 1 89  ? -3.272  -33.344 24.993  1   90.79  ? 85  GLN A OE1 1 
ATOM   712  N  NE2 . GLN A 1 89  ? -5.453  -33.646 24.734  1   75.86  ? 85  GLN A NE2 1 
ATOM   713  N  N   . ASP A 1 90  ? -5.42   -28.965 22.411  1   40.04  ? 86  ASP A N   1 
ATOM   714  C  CA  . ASP A 1 90  ? -5.45   -28.977 20.955  1   38.21  ? 86  ASP A CA  1 
ATOM   715  C  C   . ASP A 1 90  ? -5.101  -30.366 20.394  1   37.69  ? 86  ASP A C   1 
ATOM   716  O  O   . ASP A 1 90  ? -4.908  -31.327 21.135  1   42.77  ? 86  ASP A O   1 
ATOM   717  C  CB  . ASP A 1 90  ? -4.526  -27.914 20.411  1   40.62  ? 86  ASP A CB  1 
ATOM   718  C  CG  . ASP A 1 90  ? -3.056  -28.3   20.362  1   42.17  ? 86  ASP A CG  1 
ATOM   719  O  OD1 . ASP A 1 90  ? -2.367  -28.224 21.351  1   47.81  ? 86  ASP A OD1 1 
ATOM   720  O  OD2 . ASP A 1 90  ? -2.584  -28.653 19.301  1   57.68  ? 86  ASP A OD2 1 
ATOM   721  N  N   . LEU A 1 91  ? -5.185  -30.529 19.075  1   34.74  ? 87  LEU A N   1 
ATOM   722  C  CA  . LEU A 1 91  ? -5.05   -31.852 18.486  1   33.61  ? 87  LEU A CA  1 
ATOM   723  C  C   . LEU A 1 91  ? -3.576  -32.242 18.478  1   38     ? 87  LEU A C   1 
ATOM   724  O  O   . LEU A 1 91  ? -3.266  -33.414 18.696  1   41.38  ? 87  LEU A O   1 
ATOM   725  C  CB  . LEU A 1 91  ? -5.66   -31.949 17.081  1   32.55  ? 87  LEU A CB  1 
ATOM   726  C  CG  . LEU A 1 91  ? -5.546  -33.295 16.343  1   29.68  ? 87  LEU A CG  1 
ATOM   727  C  CD1 . LEU A 1 91  ? -6.252  -34.41  17.084  1   27.11  ? 87  LEU A CD1 1 
ATOM   728  C  CD2 . LEU A 1 91  ? -6.053  -33.23  14.905  1   28.04  ? 87  LEU A CD2 1 
ATOM   729  N  N   . LYS A 1 92  ? -2.679  -31.281 18.185  1   38.85  ? 88  LYS A N   1 
ATOM   730  C  CA  . LYS A 1 92  ? -1.256  -31.587 18.226  1   40.23  ? 88  LYS A CA  1 
ATOM   731  C  C   . LYS A 1 92  ? -0.906  -32.24  19.566  1   42.5   ? 88  LYS A C   1 
ATOM   732  O  O   . LYS A 1 92  ? -0.352  -33.33  19.569  1   41.89  ? 88  LYS A O   1 
ATOM   733  C  CB  . LYS A 1 92  ? -0.319  -30.42  17.905  1   41.13  ? 88  LYS A CB  1 
ATOM   734  C  CG  . LYS A 1 92  ? 1.14    -30.804 17.664  1   45.55  ? 88  LYS A CG  1 
ATOM   735  C  CD  . LYS A 1 92  ? 1.219   -32.003 16.718  1   55.25  ? 88  LYS A CD  1 
ATOM   736  C  CE  . LYS A 1 92  ? 2.534   -32.35  16.068  1   58.74  ? 88  LYS A CE  1 
ATOM   737  N  NZ  . LYS A 1 92  ? 3.515   -32.745 17.084  1   63.1   ? 88  LYS A NZ  1 
ATOM   738  N  N   . LYS A 1 93  ? -1.254  -31.612 20.683  1   45.77  ? 89  LYS A N   1 
ATOM   739  C  CA  . LYS A 1 93  ? -0.883  -32.141 22.021  1   47.08  ? 89  LYS A CA  1 
ATOM   740  C  C   . LYS A 1 93  ? -1.451  -33.549 22.229  1   45.07  ? 89  LYS A C   1 
ATOM   741  O  O   . LYS A 1 93  ? -0.775  -34.368 22.86   1   46.02  ? 89  LYS A O   1 
ATOM   742  C  CB  . LYS A 1 93  ? -1.403  -31.171 23.081  1   49.4   ? 89  LYS A CB  1 
ATOM   743  C  CG  . LYS A 1 93  ? -0.832  -29.769 23.033  1   77.45  ? 89  LYS A CG  1 
ATOM   744  C  CD  . LYS A 1 93  ? 0.645   -29.726 23.405  1   94.67  ? 89  LYS A CD  1 
ATOM   745  C  CE  . LYS A 1 93  ? 1.208   -28.341 23.357  1   101.16 ? 89  LYS A CE  1 
ATOM   746  N  NZ  . LYS A 1 93  ? 0.593   -27.475 24.367  1   97.01  ? 89  LYS A NZ  1 
ATOM   747  N  N   . PHE A 1 94  ? -2.647  -33.809 21.722  1   41.19  ? 90  PHE A N   1 
ATOM   748  C  CA  . PHE A 1 94  ? -3.292  -35.105 21.869  1   38.73  ? 90  PHE A CA  1 
ATOM   749  C  C   . PHE A 1 94  ? -2.647  -36.174 20.973  1   42.39  ? 90  PHE A C   1 
ATOM   750  O  O   . PHE A 1 94  ? -2.472  -37.319 21.399  1   42.77  ? 90  PHE A O   1 
ATOM   751  C  CB  . PHE A 1 94  ? -4.767  -34.879 21.542  1   35.55  ? 90  PHE A CB  1 
ATOM   752  C  CG  . PHE A 1 94  ? -5.577  -36.162 21.635  1   35.89  ? 90  PHE A CG  1 
ATOM   753  C  CD1 . PHE A 1 94  ? -5.781  -36.783 22.877  1   35.79  ? 90  PHE A CD1 1 
ATOM   754  C  CD2 . PHE A 1 94  ? -6.13   -36.743 20.484  1   32.47  ? 90  PHE A CD2 1 
ATOM   755  C  CE1 . PHE A 1 94  ? -6.511  -37.965 22.961  1   35.7   ? 90  PHE A CE1 1 
ATOM   756  C  CE2 . PHE A 1 94  ? -6.856  -37.924 20.573  1   32.53  ? 90  PHE A CE2 1 
ATOM   757  C  CZ  . PHE A 1 94  ? -7.055  -38.53  21.808  1   35.17  ? 90  PHE A CZ  1 
ATOM   758  N  N   . MET A 1 95  ? -2.288  -35.813 19.724  1   39.71  ? 91  MET A N   1 
ATOM   759  C  CA  . MET A 1 95  ? -1.522  -36.723 18.889  1   37.41  ? 91  MET A CA  1 
ATOM   760  C  C   . MET A 1 95  ? -0.246  -37.143 19.617  1   39.95  ? 91  MET A C   1 
ATOM   761  O  O   . MET A 1 95  ? 0.127   -38.305 19.555  1   40.14  ? 91  MET A O   1 
ATOM   762  C  CB  . MET A 1 95  ? -1.132  -36.115 17.543  1   36.86  ? 91  MET A CB  1 
ATOM   763  C  CG  . MET A 1 95  ? -2.213  -36.092 16.48   1   38.33  ? 91  MET A CG  1 
ATOM   764  S  SD  . MET A 1 95  ? -1.66   -34.871 15.27   1   43.65  ? 91  MET A SD  1 
ATOM   765  C  CE  . MET A 1 95  ? -2.948  -34.989 14.015  1   44.01  ? 91  MET A CE  1 
ATOM   766  N  N   . ASP A 1 96  ? 0.428   -36.212 20.302  1   41.52  ? 92  ASP A N   1 
ATOM   767  C  CA  . ASP A 1 96  ? 1.671   -36.547 20.975  1   42.79  ? 92  ASP A CA  1 
ATOM   768  C  C   . ASP A 1 96  ? 1.405   -37.397 22.214  1   46.51  ? 92  ASP A C   1 
ATOM   769  O  O   . ASP A 1 96  ? 2.267   -38.205 22.556  1   50.51  ? 92  ASP A O   1 
ATOM   770  C  CB  . ASP A 1 96  ? 2.445   -35.323 21.433  1   46.77  ? 92  ASP A CB  1 
ATOM   771  C  CG  . ASP A 1 96  ? 3.001   -34.406 20.349  1   49.43  ? 92  ASP A CG  1 
ATOM   772  O  OD1 . ASP A 1 96  ? 3.083   -34.846 19.187  1   46.32  ? 92  ASP A OD1 1 
ATOM   773  O  OD2 . ASP A 1 96  ? 3.304   -33.231 20.68   1   54.27  ? 92  ASP A OD2 1 
ATOM   774  N  N   . ALA A 1 97  ? 0.262   -37.192 22.908  1   44.44  ? 93  ALA A N   1 
ATOM   775  C  CA  . ALA A 1 97  ? -0.103  -38.011 24.064  1   46.96  ? 93  ALA A CA  1 
ATOM   776  C  C   . ALA A 1 97  ? -0.506  -39.439 23.654  1   49.05  ? 93  ALA A C   1 
ATOM   777  O  O   . ALA A 1 97  ? -0.419  -40.371 24.457  1   50.89  ? 93  ALA A O   1 
ATOM   778  C  CB  . ALA A 1 97  ? -1.179  -37.328 24.878  1   45.21  ? 93  ALA A CB  1 
ATOM   779  N  N   . SER A 1 98  ? -0.884  -39.605 22.376  1   46.26  ? 94  SER A N   1 
ATOM   780  C  CA  . SER A 1 98  ? -1.364  -40.849 21.796  1   48.04  ? 94  SER A CA  1 
ATOM   781  C  C   . SER A 1 98  ? -0.256  -41.693 21.162  1   52.16  ? 94  SER A C   1 
ATOM   782  O  O   . SER A 1 98  ? -0.579  -42.633 20.437  1   51.03  ? 94  SER A O   1 
ATOM   783  C  CB  . SER A 1 98  ? -2.394  -40.57  20.744  1   43.06  ? 94  SER A CB  1 
ATOM   784  O  OG  . SER A 1 98  ? -3.554  -40.081 21.381  1   44.23  ? 94  SER A OG  1 
ATOM   785  N  N   . ALA A 1 99  ? 1.021   -41.405 21.447  1   57.39  ? 95  ALA A N   1 
ATOM   786  C  CA  . ALA A 1 99  ? 2.143   -42.006 20.727  1   62.55  ? 95  ALA A CA  1 
ATOM   787  C  C   . ALA A 1 99  ? 2.123   -43.539 20.721  1   65.31  ? 95  ALA A C   1 
ATOM   788  O  O   . ALA A 1 99  ? 2.45    -44.142 19.709  1   71.75  ? 95  ALA A O   1 
ATOM   789  C  CB  . ALA A 1 99  ? 3.465   -41.485 21.246  1   61.53  ? 95  ALA A CB  1 
ATOM   790  N  N   . LEU A 1 100 ? 1.802   -44.187 21.846  1   68.57  ? 96  LEU A N   1 
ATOM   791  C  CA  . LEU A 1 100 ? 2.027   -45.629 21.939  1   69.85  ? 96  LEU A CA  1 
ATOM   792  C  C   . LEU A 1 100 ? 0.766   -46.397 21.534  1   64.56  ? 96  LEU A C   1 
ATOM   793  O  O   . LEU A 1 100 ? 0.806   -47.604 21.317  1   64.18  ? 96  LEU A O   1 
ATOM   794  C  CB  . LEU A 1 100 ? 2.499   -46.083 23.326  1   73.32  ? 96  LEU A CB  1 
ATOM   795  C  CG  . LEU A 1 100 ? 3.868   -45.604 23.844  1   77.7   ? 96  LEU A CG  1 
ATOM   796  C  CD1 . LEU A 1 100 ? 4.058   -46.161 25.261  1   77.24  ? 96  LEU A CD1 1 
ATOM   797  C  CD2 . LEU A 1 100 ? 5.104   -45.905 22.977  1   73.29  ? 96  LEU A CD2 1 
ATOM   798  N  N   . THR A 1 101 ? -0.365  -45.698 21.513  1   60.18  ? 97  THR A N   1 
ATOM   799  C  CA  . THR A 1 101 ? -1.649  -46.322 21.249  1   64.75  ? 97  THR A CA  1 
ATOM   800  C  C   . THR A 1 101 ? -2.041  -46.057 19.792  1   64.59  ? 97  THR A C   1 
ATOM   801  O  O   . THR A 1 101 ? -2.714  -46.869 19.15   1   71.25  ? 97  THR A O   1 
ATOM   802  C  CB  . THR A 1 101 ? -2.692  -45.816 22.262  1   64.8   ? 97  THR A CB  1 
ATOM   803  O  OG1 . THR A 1 101 ? -3.047  -44.453 22.014  1   54.88  ? 97  THR A OG1 1 
ATOM   804  C  CG2 . THR A 1 101 ? -2.253  -46.034 23.705  1   64.04  ? 97  THR A CG2 1 
ATOM   805  N  N   . GLY A 1 102 ? -1.56   -44.93  19.257  1   54     ? 98  GLY A N   1 
ATOM   806  C  CA  . GLY A 1 102 ? -2.227  -44.269 18.155  1   46.71  ? 98  GLY A CA  1 
ATOM   807  C  C   . GLY A 1 102 ? -3.539  -43.659 18.662  1   44.73  ? 98  GLY A C   1 
ATOM   808  O  O   . GLY A 1 102 ? -3.996  -43.921 19.781  1   41.39  ? 98  GLY A O   1 
ATOM   809  N  N   . ILE A 1 103 ? -4.111  -42.791 17.835  1   41.41  ? 99  ILE A N   1 
ATOM   810  C  CA  . ILE A 1 103 ? -5.493  -42.421 18.038  1   38.99  ? 99  ILE A CA  1 
ATOM   811  C  C   . ILE A 1 103 ? -6.363  -43.592 17.578  1   36.64  ? 99  ILE A C   1 
ATOM   812  O  O   . ILE A 1 103 ? -6.271  -44.029 16.441  1   36.08  ? 99  ILE A O   1 
ATOM   813  C  CB  . ILE A 1 103 ? -5.771  -41.151 17.223  1   40.16  ? 99  ILE A CB  1 
ATOM   814  C  CG1 . ILE A 1 103 ? -4.697  -40.076 17.463  1   39.76  ? 99  ILE A CG1 1 
ATOM   815  C  CG2 . ILE A 1 103 ? -7.189  -40.649 17.509  1   40.88  ? 99  ILE A CG2 1 
ATOM   816  C  CD1 . ILE A 1 103 ? -5.076  -38.717 16.901  1   43.52  ? 99  ILE A CD1 1 
ATOM   817  N  N   . PRO A 1 104 ? -7.288  -44.11  18.409  1   35.59  ? 100 PRO A N   1 
ATOM   818  C  CA  . PRO A 1 104 ? -8.183  -45.187 17.974  1   35.75  ? 100 PRO A CA  1 
ATOM   819  C  C   . PRO A 1 104 ? -8.99   -44.725 16.765  1   35.08  ? 100 PRO A C   1 
ATOM   820  O  O   . PRO A 1 104 ? -9.394  -43.565 16.68   1   35.9   ? 100 PRO A O   1 
ATOM   821  C  CB  . PRO A 1 104 ? -9.092  -45.411 19.192  1   35.88  ? 100 PRO A CB  1 
ATOM   822  C  CG  . PRO A 1 104 ? -8.299  -44.856 20.348  1   36.45  ? 100 PRO A CG  1 
ATOM   823  C  CD  . PRO A 1 104 ? -7.556  -43.646 19.776  1   34.92  ? 100 PRO A CD  1 
ATOM   824  N  N   . LEU A 1 105 ? -9.25   -45.655 15.845  1   39.04  ? 101 LEU A N   1 
ATOM   825  C  CA  . LEU A 1 105 ? -9.885  -45.353 14.562  1   37.51  ? 101 LEU A CA  1 
ATOM   826  C  C   . LEU A 1 105 ? -11.235 -44.671 14.773  1   36.72  ? 101 LEU A C   1 
ATOM   827  O  O   . LEU A 1 105 ? -11.534 -43.73  14.035  1   33.94  ? 101 LEU A O   1 
ATOM   828  C  CB  . LEU A 1 105 ? -10.004 -46.563 13.633  1   39.19  ? 101 LEU A CB  1 
ATOM   829  C  CG  . LEU A 1 105 ? -10.512 -46.263 12.216  1   38.55  ? 101 LEU A CG  1 
ATOM   830  C  CD1 . LEU A 1 105 ? -9.535  -45.403 11.429  1   33.13  ? 101 LEU A CD1 1 
ATOM   831  C  CD2 . LEU A 1 105 ? -10.834 -47.542 11.432  1   38.89  ? 101 LEU A CD2 1 
ATOM   832  N  N   . PRO A 1 106 ? -12.081 -45.126 15.751  1   37.47  ? 102 PRO A N   1 
ATOM   833  C  CA  . PRO A 1 106 ? -13.302 -44.407 16.11   1   35.71  ? 102 PRO A CA  1 
ATOM   834  C  C   . PRO A 1 106 ? -13.069 -42.917 16.308  1   35.27  ? 102 PRO A C   1 
ATOM   835  O  O   . PRO A 1 106 ? -13.854 -42.147 15.776  1   38.46  ? 102 PRO A O   1 
ATOM   836  C  CB  . PRO A 1 106 ? -13.82  -45.121 17.371  1   39.56  ? 102 PRO A CB  1 
ATOM   837  C  CG  . PRO A 1 106 ? -13.326 -46.556 17.193  1   38.5   ? 102 PRO A CG  1 
ATOM   838  C  CD  . PRO A 1 106 ? -11.967 -46.39  16.509  1   37.68  ? 102 PRO A CD  1 
ATOM   839  N  N   . LEU A 1 107 ? -11.972 -42.516 16.976  1   33.9   ? 103 LEU A N   1 
ATOM   840  C  CA  . LEU A 1 107 ? -11.662 -41.107 17.191  1   32.66  ? 103 LEU A CA  1 
ATOM   841  C  C   . LEU A 1 107 ? -11.167 -40.426 15.92   1   30.9   ? 103 LEU A C   1 
ATOM   842  O  O   . LEU A 1 107 ? -11.522 -39.274 15.658  1   29.29  ? 103 LEU A O   1 
ATOM   843  C  CB  . LEU A 1 107 ? -10.705 -40.822 18.343  1   33.54  ? 103 LEU A CB  1 
ATOM   844  C  CG  . LEU A 1 107 ? -11.367 -40.845 19.72   1   37.23  ? 103 LEU A CG  1 
ATOM   845  C  CD1 . LEU A 1 107 ? -10.278 -40.837 20.789  1   38.74  ? 103 LEU A CD1 1 
ATOM   846  C  CD2 . LEU A 1 107 ? -12.258 -39.638 19.874  1   36.16  ? 103 LEU A CD2 1 
ATOM   847  N  N   . ILE A 1 108 ? -10.318 -41.097 15.15   1   30.24  ? 104 ILE A N   1 
ATOM   848  C  CA  . ILE A 1 108 ? -9.872  -40.445 13.919  1   31.5   ? 104 ILE A CA  1 
ATOM   849  C  C   . ILE A 1 108 ? -11.11  -40.087 13.073  1   32.14  ? 104 ILE A C   1 
ATOM   850  O  O   . ILE A 1 108 ? -11.239 -38.986 12.522  1   30.59  ? 104 ILE A O   1 
ATOM   851  C  CB  . ILE A 1 108 ? -8.857  -41.35  13.179  1   32.13  ? 104 ILE A CB  1 
ATOM   852  C  CG1 . ILE A 1 108 ? -7.559  -41.568 13.978  1   31.95  ? 104 ILE A CG1 1 
ATOM   853  C  CG2 . ILE A 1 108 ? -8.57   -40.869 11.755  1   31.08  ? 104 ILE A CG2 1 
ATOM   854  C  CD1 . ILE A 1 108 ? -6.581  -42.54  13.334  1   30.79  ? 104 ILE A CD1 1 
ATOM   855  N  N   . LYS A 1 109 ? -12.07  -41.017 13.025  1   32.13  ? 105 LYS A N   1 
ATOM   856  C  CA  . LYS A 1 109 ? -13.233 -40.908 12.161  1   33.64  ? 105 LYS A CA  1 
ATOM   857  C  C   . LYS A 1 109 ? -14.188 -39.831 12.694  1   35.41  ? 105 LYS A C   1 
ATOM   858  O  O   . LYS A 1 109 ? -14.698 -38.998 11.944  1   34.09  ? 105 LYS A O   1 
ATOM   859  C  CB  . LYS A 1 109 ? -13.774 -42.339 12.13   1   34.41  ? 105 LYS A CB  1 
ATOM   860  C  CG  . LYS A 1 109 ? -14.584 -42.671 10.937  1   33.95  ? 105 LYS A CG  1 
ATOM   861  C  CD  . LYS A 1 109 ? -15.063 -44.108 10.975  1   36.55  ? 105 LYS A CD  1 
ATOM   862  C  CE  . LYS A 1 109 ? -14.086 -44.997 10.297  1   37.98  ? 105 LYS A CE  1 
ATOM   863  N  NZ  . LYS A 1 109 ? -14.726 -46.308 10.127  1   38.26  ? 105 LYS A NZ  1 
ATOM   864  N  N   . SER A 1 110 ? -14.388 -39.828 14.017  1   35.19  ? 106 SER A N   1 
ATOM   865  C  CA  . SER A 1 110 ? -15.219 -38.851 14.683  1   31.74  ? 106 SER A CA  1 
ATOM   866  C  C   . SER A 1 110 ? -14.641 -37.465 14.467  1   31.43  ? 106 SER A C   1 
ATOM   867  O  O   . SER A 1 110 ? -15.37  -36.534 14.1    1   31.78  ? 106 SER A O   1 
ATOM   868  C  CB  . SER A 1 110 ? -15.396 -39.17  16.132  1   32.05  ? 106 SER A CB  1 
ATOM   869  O  OG  . SER A 1 110 ? -15.865 -38.027 16.835  1   35.31  ? 106 SER A OG  1 
ATOM   870  N  N   . TYR A 1 111 ? -13.325 -37.362 14.632  1   30.74  ? 107 TYR A N   1 
ATOM   871  C  CA  . TYR A 1 111 ? -12.705 -36.05  14.54   1   32.55  ? 107 TYR A CA  1 
ATOM   872  C  C   . TYR A 1 111 ? -12.735 -35.526 13.102  1   32.28  ? 107 TYR A C   1 
ATOM   873  O  O   . TYR A 1 111 ? -12.98  -34.34  12.891  1   32.41  ? 107 TYR A O   1 
ATOM   874  C  CB  . TYR A 1 111 ? -11.287 -36.049 15.106  1   30.54  ? 107 TYR A CB  1 
ATOM   875  C  CG  . TYR A 1 111 ? -11.177 -36.039 16.62   1   29.04  ? 107 TYR A CG  1 
ATOM   876  C  CD1 . TYR A 1 111 ? -12.286 -35.797 17.428  1   31.27  ? 107 TYR A CD1 1 
ATOM   877  C  CD2 . TYR A 1 111 ? -9.939  -36.176 17.226  1   26.67  ? 107 TYR A CD2 1 
ATOM   878  C  CE1 . TYR A 1 111 ? -12.165 -35.755 18.816  1   32.06  ? 107 TYR A CE1 1 
ATOM   879  C  CE2 . TYR A 1 111 ? -9.799  -36.084 18.599  1   29.31  ? 107 TYR A CE2 1 
ATOM   880  C  CZ  . TYR A 1 111 ? -10.914 -35.895 19.402  1   31.68  ? 107 TYR A CZ  1 
ATOM   881  O  OH  . TYR A 1 111 ? -10.722 -35.837 20.757  1   35.34  ? 107 TYR A OH  1 
ATOM   882  N  N   . LEU A 1 112 ? -12.471 -36.399 12.12   1   31.45  ? 108 LEU A N   1 
ATOM   883  C  CA  . LEU A 1 112 ? -12.439 -35.96  10.733  1   29.27  ? 108 LEU A CA  1 
ATOM   884  C  C   . LEU A 1 112 ? -13.845 -35.499 10.309  1   29.75  ? 108 LEU A C   1 
ATOM   885  O  O   . LEU A 1 112 ? -14.02  -34.458 9.686   1   31.28  ? 108 LEU A O   1 
ATOM   886  C  CB  . LEU A 1 112 ? -11.883 -37.086 9.848   1   25.97  ? 108 LEU A CB  1 
ATOM   887  C  CG  . LEU A 1 112 ? -11.704 -36.693 8.37    1   26.38  ? 108 LEU A CG  1 
ATOM   888  C  CD1 . LEU A 1 112 ? -10.753 -35.507 8.221   1   22.86  ? 108 LEU A CD1 1 
ATOM   889  C  CD2 . LEU A 1 112 ? -11.32  -37.806 7.399   1   24.61  ? 108 LEU A CD2 1 
ATOM   890  N  N   . PHE A 1 113 ? -14.862 -36.297 10.64   1   29.51  ? 109 PHE A N   1 
ATOM   891  C  CA  . PHE A 1 113 ? -16.229 -35.985 10.287  1   30.28  ? 109 PHE A CA  1 
ATOM   892  C  C   . PHE A 1 113 ? -16.635 -34.638 10.874  1   30.54  ? 109 PHE A C   1 
ATOM   893  O  O   . PHE A 1 113 ? -17.31  -33.84  10.21   1   28.97  ? 109 PHE A O   1 
ATOM   894  C  CB  . PHE A 1 113 ? -17.123 -37.048 10.92   1   31.81  ? 109 PHE A CB  1 
ATOM   895  C  CG  . PHE A 1 113 ? -18.529 -37.054 10.353  1   30.35  ? 109 PHE A CG  1 
ATOM   896  C  CD1 . PHE A 1 113 ? -18.742 -37.359 9.009   1   28.03  ? 109 PHE A CD1 1 
ATOM   897  C  CD2 . PHE A 1 113 ? -19.627 -36.78  11.169  1   31.11  ? 109 PHE A CD2 1 
ATOM   898  C  CE1 . PHE A 1 113 ? -20.029 -37.397 8.487   1   28.48  ? 109 PHE A CE1 1 
ATOM   899  C  CE2 . PHE A 1 113 ? -20.922 -36.839 10.643  1   31.83  ? 109 PHE A CE2 1 
ATOM   900  C  CZ  . PHE A 1 113 ? -21.116 -37.141 9.304   1   30.34  ? 109 PHE A CZ  1 
ATOM   901  N  N   . GLN A 1 114 ? -16.251 -34.401 12.137  1   31.3   ? 110 GLN A N   1 
ATOM   902  C  CA  . GLN A 1 114 ? -16.546 -33.133 12.803  1   29.72  ? 110 GLN A CA  1 
ATOM   903  C  C   . GLN A 1 114 ? -15.815 -31.989 12.088  1   30.33  ? 110 GLN A C   1 
ATOM   904  O  O   . GLN A 1 114 ? -16.408 -30.927 11.829  1   29.16  ? 110 GLN A O   1 
ATOM   905  C  CB  . GLN A 1 114 ? -16.165 -33.21  14.277  1   25.99  ? 110 GLN A CB  1 
ATOM   906  C  CG  . GLN A 1 114 ? -17.098 -34.052 15.12   1   26.44  ? 110 GLN A CG  1 
ATOM   907  C  CD  . GLN A 1 114 ? -16.659 -34.059 16.567  1   29.57  ? 110 GLN A CD  1 
ATOM   908  O  OE1 . GLN A 1 114 ? -16.811 -33.065 17.287  1   29.62  ? 110 GLN A OE1 1 
ATOM   909  N  NE2 . GLN A 1 114 ? -16.103 -35.184 17.008  1   29.43  ? 110 GLN A NE2 1 
ATOM   910  N  N   . LEU A 1 115 ? -14.537 -32.223 11.741  1   25.56  ? 111 LEU A N   1 
ATOM   911  C  CA  . LEU A 1 115 ? -13.793 -31.171 11.061  1   26.38  ? 111 LEU A CA  1 
ATOM   912  C  C   . LEU A 1 115 ? -14.519 -30.801 9.763   1   27.78  ? 111 LEU A C   1 
ATOM   913  O  O   . LEU A 1 115 ? -14.745 -29.622 9.465   1   26.09  ? 111 LEU A O   1 
ATOM   914  C  CB  . LEU A 1 115 ? -12.335 -31.575 10.823  1   24.04  ? 111 LEU A CB  1 
ATOM   915  C  CG  . LEU A 1 115 ? -11.491 -31.696 12.1    1   23.8   ? 111 LEU A CG  1 
ATOM   916  C  CD1 . LEU A 1 115 ? -10.142 -32.367 11.883  1   22.72  ? 111 LEU A CD1 1 
ATOM   917  C  CD2 . LEU A 1 115 ? -11.333 -30.34  12.819  1   23.6   ? 111 LEU A CD2 1 
ATOM   918  N  N   . LEU A 1 116 ? -14.932 -31.835 9.014   1   26.22  ? 112 LEU A N   1 
ATOM   919  C  CA  . LEU A 1 116 ? -15.597 -31.618 7.741   1   25.52  ? 112 LEU A CA  1 
ATOM   920  C  C   . LEU A 1 116 ? -16.9   -30.853 7.955   1   28.47  ? 112 LEU A C   1 
ATOM   921  O  O   . LEU A 1 116 ? -17.194 -29.951 7.177   1   28.6   ? 112 LEU A O   1 
ATOM   922  C  CB  . LEU A 1 116 ? -15.789 -32.954 7.039   1   24.29  ? 112 LEU A CB  1 
ATOM   923  C  CG  . LEU A 1 116 ? -14.484 -33.559 6.521   1   25.6   ? 112 LEU A CG  1 
ATOM   924  C  CD1 . LEU A 1 116 ? -14.768 -35.012 6.281   1   25.95  ? 112 LEU A CD1 1 
ATOM   925  C  CD2 . LEU A 1 116 ? -13.931 -32.864 5.263   1   24.21  ? 112 LEU A CD2 1 
ATOM   926  N  N   . GLN A 1 117 ? -17.632 -31.157 9.044   1   26.66  ? 113 GLN A N   1 
ATOM   927  C  CA  . GLN A 1 117 ? -18.847 -30.416 9.315   1   27.66  ? 113 GLN A CA  1 
ATOM   928  C  C   . GLN A 1 117 ? -18.546 -28.932 9.506   1   28.62  ? 113 GLN A C   1 
ATOM   929  O  O   . GLN A 1 117 ? -19.182 -28.085 8.873   1   27.63  ? 113 GLN A O   1 
ATOM   930  C  CB  . GLN A 1 117 ? -19.556 -30.857 10.584  1   28.96  ? 113 GLN A CB  1 
ATOM   931  C  CG  . GLN A 1 117 ? -20.144 -32.253 10.474  1   31.43  ? 113 GLN A CG  1 
ATOM   932  C  CD  . GLN A 1 117 ? -21.003 -32.552 11.674  1   32.26  ? 113 GLN A CD  1 
ATOM   933  O  OE1 . GLN A 1 117 ? -21.932 -31.803 12.016  1   38.57  ? 113 GLN A OE1 1 
ATOM   934  N  NE2 . GLN A 1 117 ? -20.639 -33.623 12.347  1   30.49  ? 113 GLN A NE2 1 
ATOM   935  N  N   . GLY A 1 118 ? -17.557 -28.645 10.371  1   28.73  ? 114 GLY A N   1 
ATOM   936  C  CA  . GLY A 1 118 ? -17.151 -27.289 10.707  1   25.06  ? 114 GLY A CA  1 
ATOM   937  C  C   . GLY A 1 118 ? -16.712 -26.531 9.457   1   27.06  ? 114 GLY A C   1 
ATOM   938  O  O   . GLY A 1 118 ? -17.019 -25.355 9.282   1   26.19  ? 114 GLY A O   1 
ATOM   939  N  N   . LEU A 1 119 ? -15.966 -27.213 8.579   1   28.01  ? 115 LEU A N   1 
ATOM   940  C  CA  . LEU A 1 119 ? -15.429 -26.509 7.434   1   27.61  ? 115 LEU A CA  1 
ATOM   941  C  C   . LEU A 1 119 ? -16.528 -26.26  6.411   1   28.34  ? 115 LEU A C   1 
ATOM   942  O  O   . LEU A 1 119 ? -16.519 -25.243 5.738   1   28.56  ? 115 LEU A O   1 
ATOM   943  C  CB  . LEU A 1 119 ? -14.276 -27.311 6.853   1   29.59  ? 115 LEU A CB  1 
ATOM   944  C  CG  . LEU A 1 119 ? -13.588 -26.66  5.66    1   30.02  ? 115 LEU A CG  1 
ATOM   945  C  CD1 . LEU A 1 119 ? -12.908 -25.37  6.112   1   25.44  ? 115 LEU A CD1 1 
ATOM   946  C  CD2 . LEU A 1 119 ? -12.618 -27.697 5.086   1   30.73  ? 115 LEU A CD2 1 
ATOM   947  N  N   . ALA A 1 120 ? -17.471 -27.2   6.29    1   28.49  ? 116 ALA A N   1 
ATOM   948  C  CA  . ALA A 1 120 ? -18.512 -27.047 5.284   1   29.84  ? 116 ALA A CA  1 
ATOM   949  C  C   . ALA A 1 120 ? -19.342 -25.827 5.664   1   30.39  ? 116 ALA A C   1 
ATOM   950  O  O   . ALA A 1 120 ? -19.793 -25.07  4.795   1   32.3   ? 116 ALA A O   1 
ATOM   951  C  CB  . ALA A 1 120 ? -19.375 -28.311 5.178   1   28.6   ? 116 ALA A CB  1 
ATOM   952  N  N   . PHE A 1 121 ? -19.546 -25.684 6.98    1   26.84  ? 117 PHE A N   1 
ATOM   953  C  CA  . PHE A 1 121 ? -20.261 -24.558 7.535   1   27.61  ? 117 PHE A CA  1 
ATOM   954  C  C   . PHE A 1 121 ? -19.533 -23.252 7.183   1   28.81  ? 117 PHE A C   1 
ATOM   955  O  O   . PHE A 1 121 ? -20.177 -22.314 6.718   1   30.77  ? 117 PHE A O   1 
ATOM   956  C  CB  . PHE A 1 121 ? -20.476 -24.73  9.04    1   26.28  ? 117 PHE A CB  1 
ATOM   957  C  CG  . PHE A 1 121 ? -21.439 -23.681 9.581   1   29.28  ? 117 PHE A CG  1 
ATOM   958  C  CD1 . PHE A 1 121 ? -20.988 -22.41  9.952   1   28.23  ? 117 PHE A CD1 1 
ATOM   959  C  CD2 . PHE A 1 121 ? -22.809 -23.945 9.667   1   29.66  ? 117 PHE A CD2 1 
ATOM   960  C  CE1 . PHE A 1 121 ? -21.874 -21.451 10.446  1   30.26  ? 117 PHE A CE1 1 
ATOM   961  C  CE2 . PHE A 1 121 ? -23.696 -22.987 10.168  1   30.43  ? 117 PHE A CE2 1 
ATOM   962  C  CZ  . PHE A 1 121 ? -23.223 -21.744 10.57   1   31.64  ? 117 PHE A CZ  1 
ATOM   963  N  N   . CYS A 1 122 ? -18.208 -23.19  7.412   1   26.95  ? 118 CYS A N   1 
ATOM   964  C  CA  . CYS A 1 122 ? -17.386 -22.065 6.971   1   29.26  ? 118 CYS A CA  1 
ATOM   965  C  C   . CYS A 1 122 ? -17.634 -21.768 5.488   1   30.09  ? 118 CYS A C   1 
ATOM   966  O  O   . CYS A 1 122 ? -18.006 -20.655 5.124   1   30.83  ? 118 CYS A O   1 
ATOM   967  C  CB  . CYS A 1 122 ? -15.896 -22.293 7.208   1   28.59  ? 118 CYS A CB  1 
ATOM   968  S  SG  . CYS A 1 122 ? -15.39  -22.253 8.958   1   31.69  ? 118 CYS A SG  1 
ATOM   969  N  N   . HIS A 1 123 ? -17.495 -22.788 4.644   1   28.45  ? 119 HIS A N   1 
ATOM   970  C  CA  . HIS A 1 123 ? -17.563 -22.601 3.211   1   27.97  ? 119 HIS A CA  1 
ATOM   971  C  C   . HIS A 1 123 ? -18.961 -22.153 2.805   1   30.29  ? 119 HIS A C   1 
ATOM   972  O  O   . HIS A 1 123 ? -19.096 -21.328 1.901   1   32.63  ? 119 HIS A O   1 
ATOM   973  C  CB  . HIS A 1 123 ? -17.016 -23.832 2.492   1   26.96  ? 119 HIS A CB  1 
ATOM   974  C  CG  . HIS A 1 123 ? -15.565 -24.026 2.751   1   26.73  ? 119 HIS A CG  1 
ATOM   975  N  ND1 . HIS A 1 123 ? -14.883 -25.177 2.412   1   27.02  ? 119 HIS A ND1 1 
ATOM   976  C  CD2 . HIS A 1 123 ? -14.656 -23.179 3.286   1   26.15  ? 119 HIS A CD2 1 
ATOM   977  C  CE1 . HIS A 1 123 ? -13.608 -25.028 2.759   1   28.55  ? 119 HIS A CE1 1 
ATOM   978  N  NE2 . HIS A 1 123 ? -13.44  -23.822 3.301   1   25.49  ? 119 HIS A NE2 1 
ATOM   979  N  N   . SER A 1 124 ? -19.99  -22.666 3.488   1   30.18  ? 120 SER A N   1 
ATOM   980  C  CA  . SER A 1 124 ? -21.356 -22.285 3.16    1   33.32  ? 120 SER A CA  1 
ATOM   981  C  C   . SER A 1 124 ? -21.624 -20.843 3.573   1   32.29  ? 120 SER A C   1 
ATOM   982  O  O   . SER A 1 124 ? -22.671 -20.296 3.223   1   33.54  ? 120 SER A O   1 
ATOM   983  C  CB  . SER A 1 124 ? -22.386 -23.2   3.812   1   33.75  ? 120 SER A CB  1 
ATOM   984  O  OG  . SER A 1 124 ? -22.304 -24.501 3.263   1   36.28  ? 120 SER A OG  1 
ATOM   985  N  N   . HIS A 1 125 ? -20.731 -20.299 4.406   1   29.08  ? 121 HIS A N   1 
ATOM   986  C  CA  . HIS A 1 125 ? -20.863 -18.95  4.908   1   29.38  ? 121 HIS A CA  1 
ATOM   987  C  C   . HIS A 1 125 ? -19.771 -18.055 4.342   1   30.36  ? 121 HIS A C   1 
ATOM   988  O  O   . HIS A 1 125 ? -19.475 -17.043 4.961   1   30.7   ? 121 HIS A O   1 
ATOM   989  C  CB  . HIS A 1 125 ? -20.855 -18.957 6.43    1   30.24  ? 121 HIS A CB  1 
ATOM   990  C  CG  . HIS A 1 125 ? -22.103 -19.57  6.89    1   33.47  ? 121 HIS A CG  1 
ATOM   991  N  ND1 . HIS A 1 125 ? -22.209 -20.934 7.038   1   35.68  ? 121 HIS A ND1 1 
ATOM   992  C  CD2 . HIS A 1 125 ? -23.307 -19.068 7.142   1   35.23  ? 121 HIS A CD2 1 
ATOM   993  C  CE1 . HIS A 1 125 ? -23.447 -21.235 7.394   1   36.02  ? 121 HIS A CE1 1 
ATOM   994  N  NE2 . HIS A 1 125 ? -24.125 -20.12  7.468   1   35.44  ? 121 HIS A NE2 1 
ATOM   995  N  N   . ARG A 1 126 ? -19.228 -18.442 3.173   1   28.93  ? 122 ARG A N   1 
ATOM   996  C  CA  . ARG A 1 126 ? -18.234 -17.728 2.381   1   28.39  ? 122 ARG A CA  1 
ATOM   997  C  C   . ARG A 1 126 ? -17.01  -17.34  3.21    1   28.09  ? 122 ARG A C   1 
ATOM   998  O  O   . ARG A 1 126 ? -16.459 -16.255 3.023   1   28.81  ? 122 ARG A O   1 
ATOM   999  C  CB  . ARG A 1 126 ? -18.818 -16.592 1.528   1   29.91  ? 122 ARG A CB  1 
ATOM   1000 C  CG  . ARG A 1 126 ? -19.68  -15.528 2.202   1   29.4   ? 122 ARG A CG  1 
ATOM   1001 C  CD  . ARG A 1 126 ? -18.895 -14.456 2.951   1   29.99  ? 122 ARG A CD  1 
ATOM   1002 N  NE  . ARG A 1 126 ? -19.779 -13.451 3.568   1   31.28  ? 122 ARG A NE  1 
ATOM   1003 C  CZ  . ARG A 1 126 ? -20.162 -13.301 4.836   1   28.27  ? 122 ARG A CZ  1 
ATOM   1004 N  NH1 . ARG A 1 126 ? -19.929 -14.231 5.738   1   27.13  ? 122 ARG A NH1 1 
ATOM   1005 N  NH2 . ARG A 1 126 ? -20.815 -12.223 5.17    1   27.81  ? 122 ARG A NH2 1 
ATOM   1006 N  N   . VAL A 1 127 ? -16.551 -18.256 4.074   1   26.67  ? 123 VAL A N   1 
ATOM   1007 C  CA  . VAL A 1 127 ? -15.31  -18.052 4.815   1   26.16  ? 123 VAL A CA  1 
ATOM   1008 C  C   . VAL A 1 127 ? -14.275 -19.134 4.482   1   26.64  ? 123 VAL A C   1 
ATOM   1009 O  O   . VAL A 1 127 ? -14.559 -20.335 4.588   1   24.62  ? 123 VAL A O   1 
ATOM   1010 C  CB  . VAL A 1 127 ? -15.573 -17.992 6.334   1   26.67  ? 123 VAL A CB  1 
ATOM   1011 C  CG1 . VAL A 1 127 ? -14.265 -18.071 7.146   1   23.89  ? 123 VAL A CG1 1 
ATOM   1012 C  CG2 . VAL A 1 127 ? -16.425 -16.769 6.692   1   26.26  ? 123 VAL A CG2 1 
ATOM   1013 N  N   . LEU A 1 128 ? -13.043 -18.712 4.142   1   27.43  ? 124 LEU A N   1 
ATOM   1014 C  CA  . LEU A 1 128 ? -11.899 -19.618 4.073   1   24.61  ? 124 LEU A CA  1 
ATOM   1015 C  C   . LEU A 1 128 ? -11.159 -19.539 5.409   1   27.9   ? 124 LEU A C   1 
ATOM   1016 O  O   . LEU A 1 128 ? -10.953 -18.429 5.923   1   31.17  ? 124 LEU A O   1 
ATOM   1017 C  CB  . LEU A 1 128 ? -10.966 -19.232 2.937   1   23     ? 124 LEU A CB  1 
ATOM   1018 C  CG  . LEU A 1 128 ? -11.556 -19.2   1.53    1   25.22  ? 124 LEU A CG  1 
ATOM   1019 C  CD1 . LEU A 1 128 ? -10.394 -18.772 0.643   1   25.42  ? 124 LEU A CD1 1 
ATOM   1020 C  CD2 . LEU A 1 128 ? -11.982 -20.594 1.119   1   24.61  ? 124 LEU A CD2 1 
ATOM   1021 N  N   . HIS A 1 129 ? -10.75  -20.702 5.951   1   25.71  ? 125 HIS A N   1 
ATOM   1022 C  CA  . HIS A 1 129 ? -10.003 -20.724 7.199   1   26.05  ? 125 HIS A CA  1 
ATOM   1023 C  C   . HIS A 1 129 ? -8.534  -20.332 6.97    1   28.49  ? 125 HIS A C   1 
ATOM   1024 O  O   . HIS A 1 129 ? -8.001  -19.431 7.64    1   27.33  ? 125 HIS A O   1 
ATOM   1025 C  CB  . HIS A 1 129 ? -10.14  -22.081 7.885   1   23.89  ? 125 HIS A CB  1 
ATOM   1026 C  CG  . HIS A 1 129 ? -9.529  -22.034 9.228   1   27.28  ? 125 HIS A CG  1 
ATOM   1027 N  ND1 . HIS A 1 129 ? -8.164  -21.985 9.367   1   27.45  ? 125 HIS A ND1 1 
ATOM   1028 C  CD2 . HIS A 1 129 ? -10.048 -21.937 10.486  1   29.51  ? 125 HIS A CD2 1 
ATOM   1029 C  CE1 . HIS A 1 129 ? -7.873  -21.891 10.665  1   30.85  ? 125 HIS A CE1 1 
ATOM   1030 N  NE2 . HIS A 1 129 ? -8.998  -21.863 11.366  1   28.73  ? 125 HIS A NE2 1 
ATOM   1031 N  N   . ARG A 1 130 ? -7.867  -21.08  6.076   1   27.24  ? 126 ARG A N   1 
ATOM   1032 C  CA  . ARG A 1 130 ? -6.554  -20.749 5.524   1   30.45  ? 126 ARG A CA  1 
ATOM   1033 C  C   . ARG A 1 130 ? -5.436  -20.929 6.552   1   32.01  ? 126 ARG A C   1 
ATOM   1034 O  O   . ARG A 1 130 ? -4.326  -20.418 6.349   1   36.3   ? 126 ARG A O   1 
ATOM   1035 C  CB  . ARG A 1 130 ? -6.443  -19.326 4.948   1   27.37  ? 126 ARG A CB  1 
ATOM   1036 C  CG  . ARG A 1 130 ? -7.514  -18.973 3.931   1   26.79  ? 126 ARG A CG  1 
ATOM   1037 C  CD  . ARG A 1 130 ? -7.187  -17.75  3.135   1   29.26  ? 126 ARG A CD  1 
ATOM   1038 N  NE  . ARG A 1 130 ? -7.039  -16.622 4.053   1   31.83  ? 126 ARG A NE  1 
ATOM   1039 C  CZ  . ARG A 1 130 ? -6.699  -15.39  3.677   1   32.05  ? 126 ARG A CZ  1 
ATOM   1040 N  NH1 . ARG A 1 130 ? -6.362  -15.152 2.418   1   29.08  ? 126 ARG A NH1 1 
ATOM   1041 N  NH2 . ARG A 1 130 ? -6.704  -14.412 4.583   1   31.29  ? 126 ARG A NH2 1 
ATOM   1042 N  N   . ASP A 1 131 ? -5.723  -21.62  7.667   1   29.8   ? 127 ASP A N   1 
ATOM   1043 C  CA  . ASP A 1 131 ? -4.634  -22.046 8.531   1   28.54  ? 127 ASP A CA  1 
ATOM   1044 C  C   . ASP A 1 131 ? -5.004  -23.293 9.323   1   28.56  ? 127 ASP A C   1 
ATOM   1045 O  O   . ASP A 1 131 ? -4.691  -23.359 10.514  1   31.11  ? 127 ASP A O   1 
ATOM   1046 C  CB  . ASP A 1 131 ? -4.166  -20.952 9.475   1   29.51  ? 127 ASP A CB  1 
ATOM   1047 C  CG  . ASP A 1 131 ? -2.77   -21.168 10.025  1   31.55  ? 127 ASP A CG  1 
ATOM   1048 O  OD1 . ASP A 1 131 ? -1.989  -21.931 9.399   1   33.86  ? 127 ASP A OD1 1 
ATOM   1049 O  OD2 . ASP A 1 131 ? -2.478  -20.567 11.056  1   34.36  ? 127 ASP A OD2 1 
ATOM   1050 N  N   . LEU A 1 132 ? -5.619  -24.289 8.66    1   26.42  ? 128 LEU A N   1 
ATOM   1051 C  CA  . LEU A 1 132 ? -5.947  -25.537 9.336   1   27.05  ? 128 LEU A CA  1 
ATOM   1052 C  C   . LEU A 1 132 ? -4.673  -26.369 9.565   1   29.77  ? 128 LEU A C   1 
ATOM   1053 O  O   . LEU A 1 132 ? -3.906  -26.633 8.635   1   33.96  ? 128 LEU A O   1 
ATOM   1054 C  CB  . LEU A 1 132 ? -7.011  -26.267 8.519   1   25.86  ? 128 LEU A CB  1 
ATOM   1055 C  CG  . LEU A 1 132 ? -8.365  -25.561 8.423   1   25.76  ? 128 LEU A CG  1 
ATOM   1056 C  CD1 . LEU A 1 132 ? -9.24   -26.272 7.404   1   26.77  ? 128 LEU A CD1 1 
ATOM   1057 C  CD2 . LEU A 1 132 ? -9.054  -25.434 9.796   1   22.66  ? 128 LEU A CD2 1 
ATOM   1058 N  N   . LYS A 1 133 ? -4.416  -26.692 10.834  1   27.81  ? 129 LYS A N   1 
ATOM   1059 C  CA  . LYS A 1 133 ? -3.295  -27.492 11.283  1   27.02  ? 129 LYS A CA  1 
ATOM   1060 C  C   . LYS A 1 133 ? -3.66   -27.958 12.684  1   28     ? 129 LYS A C   1 
ATOM   1061 O  O   . LYS A 1 133 ? -4.55   -27.361 13.289  1   30.94  ? 129 LYS A O   1 
ATOM   1062 C  CB  . LYS A 1 133 ? -1.965  -26.733 11.289  1   26.63  ? 129 LYS A CB  1 
ATOM   1063 C  CG  . LYS A 1 133 ? -2.024  -25.459 12.073  1   27.08  ? 129 LYS A CG  1 
ATOM   1064 C  CD  . LYS A 1 133 ? -0.68   -24.765 12.141  1   29.01  ? 129 LYS A CD  1 
ATOM   1065 C  CE  . LYS A 1 133 ? -0.75   -23.416 12.8    1   32.22  ? 129 LYS A CE  1 
ATOM   1066 N  NZ  . LYS A 1 133 ? 0.571   -22.755 12.751  1   34.56  ? 129 LYS A NZ  1 
ATOM   1067 N  N   . PRO A 1 134 ? -3.053  -29.056 13.205  1   29.14  ? 130 PRO A N   1 
ATOM   1068 C  CA  . PRO A 1 134 ? -3.524  -29.662 14.458  1   29.55  ? 130 PRO A CA  1 
ATOM   1069 C  C   . PRO A 1 134 ? -3.504  -28.674 15.618  1   31.38  ? 130 PRO A C   1 
ATOM   1070 O  O   . PRO A 1 134 ? -4.325  -28.783 16.518  1   31.32  ? 130 PRO A O   1 
ATOM   1071 C  CB  . PRO A 1 134 ? -2.607  -30.876 14.689  1   28.74  ? 130 PRO A CB  1 
ATOM   1072 C  CG  . PRO A 1 134 ? -2.036  -31.158 13.293  1   30.13  ? 130 PRO A CG  1 
ATOM   1073 C  CD  . PRO A 1 134 ? -1.948  -29.816 12.58   1   28.47  ? 130 PRO A CD  1 
ATOM   1074 N  N   . GLN A 1 135 ? -2.57   -27.712 15.568  1   32.45  ? 131 GLN A N   1 
ATOM   1075 C  CA  . GLN A 1 135 ? -2.386  -26.75  16.642  1   32.05  ? 131 GLN A CA  1 
ATOM   1076 C  C   . GLN A 1 135 ? -3.578  -25.796 16.692  1   32.24  ? 131 GLN A C   1 
ATOM   1077 O  O   . GLN A 1 135 ? -3.781  -25.142 17.696  1   31.76  ? 131 GLN A O   1 
ATOM   1078 C  CB  . GLN A 1 135 ? -1.111  -25.924 16.516  1   33.78  ? 131 GLN A CB  1 
ATOM   1079 C  CG  . GLN A 1 135 ? 0.188   -26.723 16.549  1   39.87  ? 131 GLN A CG  1 
ATOM   1080 C  CD  . GLN A 1 135 ? 0.52    -27.498 15.285  1   41.62  ? 131 GLN A CD  1 
ATOM   1081 O  OE1 . GLN A 1 135 ? -0.249  -27.575 14.316  1   40.19  ? 131 GLN A OE1 1 
ATOM   1082 N  NE2 . GLN A 1 135 ? 1.669   -28.151 15.313  1   40.23  ? 131 GLN A NE2 1 
ATOM   1083 N  N   . ASN A 1 136 ? -4.357  -25.688 15.609  1   31.09  ? 132 ASN A N   1 
ATOM   1084 C  CA  . ASN A 1 136 ? -5.486  -24.756 15.579  1   32.51  ? 132 ASN A CA  1 
ATOM   1085 C  C   . ASN A 1 136 ? -6.818  -25.524 15.681  1   34.24  ? 132 ASN A C   1 
ATOM   1086 O  O   . ASN A 1 136 ? -7.887  -24.971 15.396  1   35.19  ? 132 ASN A O   1 
ATOM   1087 C  CB  . ASN A 1 136 ? -5.439  -23.842 14.351  1   29.16  ? 132 ASN A CB  1 
ATOM   1088 C  CG  . ASN A 1 136 ? -4.298  -22.839 14.341  1   32.65  ? 132 ASN A CG  1 
ATOM   1089 O  OD1 . ASN A 1 136 ? -3.709  -22.515 15.385  1   34.39  ? 132 ASN A OD1 1 
ATOM   1090 N  ND2 . ASN A 1 136 ? -3.95   -22.336 13.158  1   29.28  ? 132 ASN A ND2 1 
ATOM   1091 N  N   . LEU A 1 137 ? -6.761  -26.815 16.056  1   31.44  ? 133 LEU A N   1 
ATOM   1092 C  CA  . LEU A 1 137 ? -7.963  -27.617 16.235  1   29.25  ? 133 LEU A CA  1 
ATOM   1093 C  C   . LEU A 1 137 ? -8.063  -28.016 17.714  1   33.62  ? 133 LEU A C   1 
ATOM   1094 O  O   . LEU A 1 137 ? -7.128  -28.591 18.285  1   37.77  ? 133 LEU A O   1 
ATOM   1095 C  CB  . LEU A 1 137 ? -7.844  -28.812 15.299  1   27.64  ? 133 LEU A CB  1 
ATOM   1096 C  CG  . LEU A 1 137 ? -7.736  -28.481 13.806  1   28.57  ? 133 LEU A CG  1 
ATOM   1097 C  CD1 . LEU A 1 137 ? -7.706  -29.721 12.911  1   28.2   ? 133 LEU A CD1 1 
ATOM   1098 C  CD2 . LEU A 1 137 ? -8.826  -27.513 13.352  1   28.36  ? 133 LEU A CD2 1 
ATOM   1099 N  N   . LEU A 1 138 ? -9.165  -27.613 18.363  1   30.89  ? 134 LEU A N   1 
ATOM   1100 C  CA  . LEU A 1 138 ? -9.333  -27.762 19.793  1   31.24  ? 134 LEU A CA  1 
ATOM   1101 C  C   . LEU A 1 138 ? -10.265 -28.929 20.11   1   30.97  ? 134 LEU A C   1 
ATOM   1102 O  O   . LEU A 1 138 ? -11.301 -29.09  19.477  1   28.97  ? 134 LEU A O   1 
ATOM   1103 C  CB  . LEU A 1 138 ? -9.843  -26.439 20.371  1   30.9   ? 134 LEU A CB  1 
ATOM   1104 C  CG  . LEU A 1 138 ? -8.867  -25.255 20.287  1   29.25  ? 134 LEU A CG  1 
ATOM   1105 C  CD1 . LEU A 1 138 ? -9.453  -24.01  20.887  1   26.87  ? 134 LEU A CD1 1 
ATOM   1106 C  CD2 . LEU A 1 138 ? -7.445  -25.501 20.783  1   29.14  ? 134 LEU A CD2 1 
ATOM   1107 N  N   . ILE A 1 139 ? -9.891  -29.707 21.131  1   30.09  ? 135 ILE A N   1 
ATOM   1108 C  CA  . ILE A 1 139 ? -10.67  -30.867 21.532  1   31.6   ? 135 ILE A CA  1 
ATOM   1109 C  C   . ILE A 1 139 ? -11.085 -30.656 22.983  1   33.47  ? 135 ILE A C   1 
ATOM   1110 O  O   . ILE A 1 139 ? -10.289 -30.145 23.772  1   34.11  ? 135 ILE A O   1 
ATOM   1111 C  CB  . ILE A 1 139 ? -9.895  -32.2   21.344  1   30.43  ? 135 ILE A CB  1 
ATOM   1112 C  CG1 . ILE A 1 139 ? -8.553  -32.223 22.137  1   31.14  ? 135 ILE A CG1 1 
ATOM   1113 C  CG2 . ILE A 1 139 ? -9.68   -32.494 19.862  1   27.37  ? 135 ILE A CG2 1 
ATOM   1114 C  CD1 . ILE A 1 139 ? -7.915  -33.583 22.256  1   27.8   ? 135 ILE A CD1 1 
ATOM   1115 N  N   . ASN A 1 140 ? -12.304 -31.095 23.324  1   32.23  ? 136 ASN A N   1 
ATOM   1116 C  CA  . ASN A 1 140 ? -12.774 -31.06  24.708  1   32.98  ? 136 ASN A CA  1 
ATOM   1117 C  C   . ASN A 1 140 ? -12.865 -32.486 25.257  1   34.32  ? 136 ASN A C   1 
ATOM   1118 O  O   . ASN A 1 140 ? -12.474 -33.456 24.601  1   32.49  ? 136 ASN A O   1 
ATOM   1119 C  CB  . ASN A 1 140 ? -14.102 -30.33  24.865  1   32.28  ? 136 ASN A CB  1 
ATOM   1120 C  CG  . ASN A 1 140 ? -15.26  -31.055 24.22   1   34.88  ? 136 ASN A CG  1 
ATOM   1121 O  OD1 . ASN A 1 140 ? -15.225 -32.271 23.963  1   35.59  ? 136 ASN A OD1 1 
ATOM   1122 N  ND2 . ASN A 1 140 ? -16.294 -30.289 23.911  1   36.67  ? 136 ASN A ND2 1 
ATOM   1123 N  N   . THR A 1 141 ? -13.372 -32.606 26.486  1   34.8   ? 137 THR A N   1 
ATOM   1124 C  CA  . THR A 1 141 ? -13.361 -33.903 27.141  1   35.99  ? 137 THR A CA  1 
ATOM   1125 C  C   . THR A 1 141 ? -14.6   -34.68  26.71   1   37.77  ? 137 THR A C   1 
ATOM   1126 O  O   . THR A 1 141 ? -14.752 -35.839 27.075  1   41.99  ? 137 THR A O   1 
ATOM   1127 C  CB  . THR A 1 141 ? -13.279 -33.751 28.659  1   37.34  ? 137 THR A CB  1 
ATOM   1128 O  OG1 . THR A 1 141 ? -14.278 -32.801 29.013  1   39.06  ? 137 THR A OG1 1 
ATOM   1129 C  CG2 . THR A 1 141 ? -11.948 -33.193 29.123  1   37.03  ? 137 THR A CG2 1 
ATOM   1130 N  N   . GLU A 1 142 ? -15.475 -34.045 25.931  1   35.86  ? 138 GLU A N   1 
ATOM   1131 C  CA  . GLU A 1 142 ? -16.73  -34.679 25.562  1   38.86  ? 138 GLU A CA  1 
ATOM   1132 C  C   . GLU A 1 142 ? -16.635 -35.326 24.175  1   37.32  ? 138 GLU A C   1 
ATOM   1133 O  O   . GLU A 1 142 ? -17.556 -36.007 23.747  1   38.6   ? 138 GLU A O   1 
ATOM   1134 C  CB  . GLU A 1 142 ? -17.891 -33.683 25.674  1   40.7   ? 138 GLU A CB  1 
ATOM   1135 C  CG  . GLU A 1 142 ? -18.306 -33.443 27.12   1   48.45  ? 138 GLU A CG  1 
ATOM   1136 C  CD  . GLU A 1 142 ? -18.876 -34.695 27.774  1   59.89  ? 138 GLU A CD  1 
ATOM   1137 O  OE1 . GLU A 1 142 ? -19.977 -35.172 27.41   1   61.86  ? 138 GLU A OE1 1 
ATOM   1138 O  OE2 . GLU A 1 142 ? -18.18  -35.222 28.661  1   71.85  ? 138 GLU A OE2 1 
ATOM   1139 N  N   . GLY A 1 143 ? -15.54  -35.092 23.458  1   35.79  ? 139 GLY A N   1 
ATOM   1140 C  CA  . GLY A 1 143 ? -15.342 -35.713 22.163  1   34.56  ? 139 GLY A CA  1 
ATOM   1141 C  C   . GLY A 1 143 ? -15.513 -34.696 21.035  1   34.39  ? 139 GLY A C   1 
ATOM   1142 O  O   . GLY A 1 143 ? -15.405 -35.026 19.856  1   34.69  ? 139 GLY A O   1 
ATOM   1143 N  N   . ALA A 1 144 ? -15.798 -33.442 21.384  1   32.17  ? 140 ALA A N   1 
ATOM   1144 C  CA  . ALA A 1 144 ? -15.897 -32.453 20.329  1   29.2   ? 140 ALA A CA  1 
ATOM   1145 C  C   . ALA A 1 144 ? -14.489 -32.122 19.831  1   27.46  ? 140 ALA A C   1 
ATOM   1146 O  O   . ALA A 1 144 ? -13.541 -32.213 20.591  1   32.06  ? 140 ALA A O   1 
ATOM   1147 C  CB  . ALA A 1 144 ? -16.593 -31.243 20.896  1   26.95  ? 140 ALA A CB  1 
ATOM   1148 N  N   . ILE A 1 145 ? -14.345 -31.793 18.548  1   27.45  ? 141 ILE A N   1 
ATOM   1149 C  CA  . ILE A 1 145 ? -13.208 -31.057 18.016  1   26.47  ? 141 ILE A CA  1 
ATOM   1150 C  C   . ILE A 1 145 ? -13.754 -29.852 17.244  1   28.1   ? 141 ILE A C   1 
ATOM   1151 O  O   . ILE A 1 145 ? -14.843 -29.918 16.653  1   28.04  ? 141 ILE A O   1 
ATOM   1152 C  CB  . ILE A 1 145 ? -12.334 -31.946 17.119  1   26.67  ? 141 ILE A CB  1 
ATOM   1153 C  CG1 . ILE A 1 145 ? -10.953 -31.285 16.802  1   26.81  ? 141 ILE A CG1 1 
ATOM   1154 C  CG2 . ILE A 1 145 ? -13.075 -32.3   15.827  1   26.46  ? 141 ILE A CG2 1 
ATOM   1155 C  CD1 . ILE A 1 145 ? -9.947  -32.225 16.145  1   23.22  ? 141 ILE A CD1 1 
ATOM   1156 N  N   . LYS A 1 146 ? -12.987 -28.748 17.246  1   28.19  ? 142 LYS A N   1 
ATOM   1157 C  CA  . LYS A 1 146 ? -13.475 -27.479 16.731  1   27.64  ? 142 LYS A CA  1 
ATOM   1158 C  C   . LYS A 1 146 ? -12.34  -26.716 16.048  1   29.93  ? 142 LYS A C   1 
ATOM   1159 O  O   . LYS A 1 146 ? -11.225 -26.659 16.57   1   29.26  ? 142 LYS A O   1 
ATOM   1160 C  CB  . LYS A 1 146 ? -14.063 -26.64  17.869  1   25.6   ? 142 LYS A CB  1 
ATOM   1161 C  CG  . LYS A 1 146 ? -15.078 -27.397 18.727  1   27.13  ? 142 LYS A CG  1 
ATOM   1162 C  CD  . LYS A 1 146 ? -16.034 -26.474 19.469  1   28.2   ? 142 LYS A CD  1 
ATOM   1163 C  CE  . LYS A 1 146 ? -16.774 -27.184 20.547  1   28.24  ? 142 LYS A CE  1 
ATOM   1164 N  NZ  . LYS A 1 146 ? -17.959 -26.416 20.947  1   28.09  ? 142 LYS A NZ  1 
ATOM   1165 N  N   . LEU A 1 147 ? -12.661 -26.139 14.874  1   29.76  ? 143 LEU A N   1 
ATOM   1166 C  CA  . LEU A 1 147 ? -11.792 -25.221 14.162  1   30.9   ? 143 LEU A CA  1 
ATOM   1167 C  C   . LEU A 1 147 ? -11.599 -24.005 15.062  1   30.84  ? 143 LEU A C   1 
ATOM   1168 O  O   . LEU A 1 147 ? -12.592 -23.431 15.495  1   30.85  ? 143 LEU A O   1 
ATOM   1169 C  CB  . LEU A 1 147 ? -12.402 -24.742 12.837  1   33.74  ? 143 LEU A CB  1 
ATOM   1170 C  CG  . LEU A 1 147 ? -13.004 -25.744 11.847  1   35.5   ? 143 LEU A CG  1 
ATOM   1171 C  CD1 . LEU A 1 147 ? -13.044 -25.105 10.447  1   33.45  ? 143 LEU A CD1 1 
ATOM   1172 C  CD2 . LEU A 1 147 ? -12.378 -27.114 11.828  1   33.3   ? 143 LEU A CD2 1 
ATOM   1173 N  N   . ALA A 1 148 ? -10.336 -23.61  15.3    1   30.75  ? 144 ALA A N   1 
ATOM   1174 C  CA  . ALA A 1 148 ? -10.008 -22.407 16.057  1   30.28  ? 144 ALA A CA  1 
ATOM   1175 C  C   . ALA A 1 148 ? -9.049  -21.543 15.242  1   31.34  ? 144 ALA A C   1 
ATOM   1176 O  O   . ALA A 1 148 ? -8.681  -21.897 14.102  1   29.88  ? 144 ALA A O   1 
ATOM   1177 C  CB  . ALA A 1 148 ? -9.419  -22.757 17.397  1   27.25  ? 144 ALA A CB  1 
ATOM   1178 N  N   . ASP A 1 149 ? -8.658  -20.425 15.862  1   31.04  ? 145 ASP A N   1 
ATOM   1179 C  CA  . ASP A 1 149 ? -7.705  -19.478 15.296  1   36.21  ? 145 ASP A CA  1 
ATOM   1180 C  C   . ASP A 1 149 ? -8.12   -19.009 13.893  1   33.57  ? 145 ASP A C   1 
ATOM   1181 O  O   . ASP A 1 149 ? -7.596  -19.517 12.928  1   33.28  ? 145 ASP A O   1 
ATOM   1182 C  CB  . ASP A 1 149 ? -6.281  -20.006 15.359  1   36.59  ? 145 ASP A CB  1 
ATOM   1183 C  CG  . ASP A 1 149 ? -5.225  -18.913 15.497  1   49.35  ? 145 ASP A CG  1 
ATOM   1184 O  OD1 . ASP A 1 149 ? -5.567  -17.696 15.296  1   48.41  ? 145 ASP A OD1 1 
ATOM   1185 O  OD2 . ASP A 1 149 ? -4.067  -19.275 15.847  1   53.82  ? 145 ASP A OD2 1 
ATOM   1186 N  N   . PHE A 1 150 ? -8.972  -17.986 13.823  1   34.57  ? 146 PHE A N   1 
ATOM   1187 C  CA  . PHE A 1 150 ? -9.498  -17.469 12.534  1   34.44  ? 146 PHE A CA  1 
ATOM   1188 C  C   . PHE A 1 150 ? -8.854  -16.125 12.187  1   38.38  ? 146 PHE A C   1 
ATOM   1189 O  O   . PHE A 1 150 ? -9.532  -15.288 11.58   1   40.67  ? 146 PHE A O   1 
ATOM   1190 C  CB  . PHE A 1 150 ? -11.02  -17.381 12.664  1   31.41  ? 146 PHE A CB  1 
ATOM   1191 C  CG  . PHE A 1 150 ? -11.788 -18.665 12.396  1   31     ? 146 PHE A CG  1 
ATOM   1192 C  CD1 . PHE A 1 150 ? -11.834 -19.68  13.343  1   30.36  ? 146 PHE A CD1 1 
ATOM   1193 C  CD2 . PHE A 1 150 ? -12.471 -18.847 11.202  1   30.88  ? 146 PHE A CD2 1 
ATOM   1194 C  CE1 . PHE A 1 150 ? -12.538 -20.843 13.095  1   29.06  ? 146 PHE A CE1 1 
ATOM   1195 C  CE2 . PHE A 1 150 ? -13.171 -20.014 10.961  1   30.38  ? 146 PHE A CE2 1 
ATOM   1196 C  CZ  . PHE A 1 150 ? -13.204 -21.007 11.907  1   29.26  ? 146 PHE A CZ  1 
ATOM   1197 N  N   . GLY A 1 151 ? -7.579  -15.941 12.527  1   35.89  ? 147 GLY A N   1 
ATOM   1198 C  CA  . GLY A 1 151 ? -6.86   -14.686 12.242  1   37.26  ? 147 GLY A CA  1 
ATOM   1199 C  C   . GLY A 1 151 ? -6.375  -14.62  10.814  1   37.77  ? 147 GLY A C   1 
ATOM   1200 O  O   . GLY A 1 151 ? -6.252  -13.506 10.299  1   39.52  ? 147 GLY A O   1 
ATOM   1201 N  N   . LEU A 1 152 ? -6.155  -15.77  10.182  1   36.83  ? 148 LEU A N   1 
ATOM   1202 C  CA  . LEU A 1 152 ? -5.731  -15.826 8.761   1   38.09  ? 148 LEU A CA  1 
ATOM   1203 C  C   . LEU A 1 152 ? -6.95   -16.1   7.879   1   36.1   ? 148 LEU A C   1 
ATOM   1204 O  O   . LEU A 1 152 ? -6.765  -16.42  6.703   1   37.24  ? 148 LEU A O   1 
ATOM   1205 C  CB  . LEU A 1 152 ? -4.671  -16.911 8.61    1   41.09  ? 148 LEU A CB  1 
ATOM   1206 C  CG  . LEU A 1 152 ? -3.488  -16.568 7.702   1   47.83  ? 148 LEU A CG  1 
ATOM   1207 C  CD1 . LEU A 1 152 ? -2.692  -15.441 8.327   1   43.48  ? 148 LEU A CD1 1 
ATOM   1208 C  CD2 . LEU A 1 152 ? -2.612  -17.785 7.478   1   49     ? 148 LEU A CD2 1 
ATOM   1209 N  N   . ALA A 1 153 ? -8.145  -15.955 8.431   1   34.5   ? 149 ALA A N   1 
ATOM   1210 C  CA  . ALA A 1 153 ? -9.378  -16.285 7.691   1   33.16  ? 149 ALA A CA  1 
ATOM   1211 C  C   . ALA A 1 153 ? -9.831  -15.118 6.821   1   31.93  ? 149 ALA A C   1 
ATOM   1212 O  O   . ALA A 1 153 ? -9.402  -13.982 7.036   1   35.08  ? 149 ALA A O   1 
ATOM   1213 C  CB  . ALA A 1 153 ? -10.443 -16.699 8.666   1   31.51  ? 149 ALA A CB  1 
ATOM   1214 N  N   . ARG A 1 154 ? -10.674 -15.423 5.846   1   29.16  ? 150 ARG A N   1 
ATOM   1215 C  CA  . ARG A 1 154 ? -11.114 -14.366 4.911   1   31.44  ? 150 ARG A CA  1 
ATOM   1216 C  C   . ARG A 1 154 ? -12.515 -14.617 4.37    1   32.25  ? 150 ARG A C   1 
ATOM   1217 O  O   . ARG A 1 154 ? -12.854 -15.769 4.072   1   34.97  ? 150 ARG A O   1 
ATOM   1218 C  CB  . ARG A 1 154 ? -10.215 -14.249 3.682   1   33.59  ? 150 ARG A CB  1 
ATOM   1219 C  CG  . ARG A 1 154 ? -9.848  -12.819 3.328   1   39.18  ? 150 ARG A CG  1 
ATOM   1220 C  CD  . ARG A 1 154 ? -9.334  -12.852 1.915   1   38.33  ? 150 ARG A CD  1 
ATOM   1221 N  NE  . ARG A 1 154 ? -9.752  -11.673 1.157   1   40.17  ? 150 ARG A NE  1 
ATOM   1222 C  CZ  . ARG A 1 154 ? -9.332  -10.448 1.393   1   41.73  ? 150 ARG A CZ  1 
ATOM   1223 N  NH1 . ARG A 1 154 ? -10.144 -9.6    1.983   1   41.59  ? 150 ARG A NH1 1 
ATOM   1224 N  NH2 . ARG A 1 154 ? -8.117  -10.078 1.04    1   44.71  ? 150 ARG A NH2 1 
ATOM   1225 N  N   . ALA A 1 155 ? -13.286 -13.546 4.253   1   32.65  ? 151 ALA A N   1 
ATOM   1226 C  CA  . ALA A 1 155 ? -14.604 -13.641 3.647   1   31.05  ? 151 ALA A CA  1 
ATOM   1227 C  C   . ALA A 1 155 ? -14.403 -13.557 2.142   1   30.65  ? 151 ALA A C   1 
ATOM   1228 O  O   . ALA A 1 155 ? -13.779 -12.621 1.675   1   31.57  ? 151 ALA A O   1 
ATOM   1229 C  CB  . ALA A 1 155 ? -15.483 -12.531 4.178   1   32.35  ? 151 ALA A CB  1 
ATOM   1230 N  N   . PHE A 1 156 ? -14.837 -14.585 1.413   1   31.85  ? 152 PHE A N   1 
ATOM   1231 C  CA  . PHE A 1 156 ? -14.629 -14.643 -0.027  1   34.38  ? 152 PHE A CA  1 
ATOM   1232 C  C   . PHE A 1 156 ? -15.908 -14.259 -0.772  1   38.76  ? 152 PHE A C   1 
ATOM   1233 O  O   . PHE A 1 156 ? -16.995 -14.184 -0.181  1   43.08  ? 152 PHE A O   1 
ATOM   1234 C  CB  . PHE A 1 156 ? -14.011 -15.947 -0.531  1   30.91  ? 152 PHE A CB  1 
ATOM   1235 C  CG  . PHE A 1 156 ? -14.837 -17.219 -0.367  1   32.6   ? 152 PHE A CG  1 
ATOM   1236 C  CD1 . PHE A 1 156 ? -14.785 -17.96  0.823   1   31.84  ? 152 PHE A CD1 1 
ATOM   1237 C  CD2 . PHE A 1 156 ? -15.649 -17.685 -1.407  1   31.2   ? 152 PHE A CD2 1 
ATOM   1238 C  CE1 . PHE A 1 156 ? -15.538 -19.124 0.968   1   30.1   ? 152 PHE A CE1 1 
ATOM   1239 C  CE2 . PHE A 1 156 ? -16.4   -18.846 -1.272  1   30.48  ? 152 PHE A CE2 1 
ATOM   1240 C  CZ  . PHE A 1 156 ? -16.329 -19.58  -0.094  1   32.27  ? 152 PHE A CZ  1 
ATOM   1241 N  N   . GLY A 1 157 ? -15.744 -13.988 -2.079  1   37.47  ? 153 GLY A N   1 
ATOM   1242 C  CA  . GLY A 1 157 ? -16.857 -13.75  -2.981  1   36.85  ? 153 GLY A CA  1 
ATOM   1243 C  C   . GLY A 1 157 ? -16.91  -14.864 -4.022  1   35.82  ? 153 GLY A C   1 
ATOM   1244 O  O   . GLY A 1 157 ? -16.031 -15.706 -4.031  1   36.22  ? 153 GLY A O   1 
ATOM   1245 N  N   . VAL A 1 158 ? -17.93  -14.868 -4.888  1   33.95  ? 154 VAL A N   1 
ATOM   1246 C  CA  . VAL A 1 158 ? -18.12  -15.911 -5.88   1   32.04  ? 154 VAL A CA  1 
ATOM   1247 C  C   . VAL A 1 158 ? -18.277 -15.249 -7.253  1   34.3   ? 154 VAL A C   1 
ATOM   1248 O  O   . VAL A 1 158 ? -19.177 -14.413 -7.465  1   36.22  ? 154 VAL A O   1 
ATOM   1249 C  CB  . VAL A 1 158 ? -19.364 -16.747 -5.495  1   33.22  ? 154 VAL A CB  1 
ATOM   1250 C  CG1 . VAL A 1 158 ? -19.668 -17.844 -6.525  1   33.47  ? 154 VAL A CG1 1 
ATOM   1251 C  CG2 . VAL A 1 158 ? -19.329 -17.279 -4.049  1   28.46  ? 154 VAL A CG2 1 
ATOM   1252 N  N   . PRO A 1 159 ? -17.36  -15.513 -8.215  1   32.57  ? 155 PRO A N   1 
ATOM   1253 C  CA  . PRO A 1 159 ? -16.165 -16.325 -7.98   1   31.44  ? 155 PRO A CA  1 
ATOM   1254 C  C   . PRO A 1 159 ? -15.116 -15.597 -7.14   1   32.93  ? 155 PRO A C   1 
ATOM   1255 O  O   . PRO A 1 159 ? -15.29  -14.429 -6.803  1   33.06  ? 155 PRO A O   1 
ATOM   1256 C  CB  . PRO A 1 159 ? -15.641 -16.59  -9.423  1   30.35  ? 155 PRO A CB  1 
ATOM   1257 C  CG  . PRO A 1 159 ? -16.046 -15.367 -10.209 1   31.95  ? 155 PRO A CG  1 
ATOM   1258 C  CD  . PRO A 1 159 ? -17.385 -14.947 -9.576  1   34.51  ? 155 PRO A CD  1 
ATOM   1259 N  N   . VAL A 1 160 ? -14.011 -16.287 -6.815  1   32.25  ? 156 VAL A N   1 
ATOM   1260 C  CA  . VAL A 1 160 ? -13.008 -15.736 -5.908  1   31.6   ? 156 VAL A CA  1 
ATOM   1261 C  C   . VAL A 1 160 ? -12.106 -14.706 -6.614  1   34.79  ? 156 VAL A C   1 
ATOM   1262 O  O   . VAL A 1 160 ? -11.887 -14.745 -7.826  1   38.56  ? 156 VAL A O   1 
ATOM   1263 C  CB  . VAL A 1 160 ? -12.192 -16.875 -5.252  1   29.41  ? 156 VAL A CB  1 
ATOM   1264 C  CG1 . VAL A 1 160 ? -13.037 -17.791 -4.371  1   25.29  ? 156 VAL A CG1 1 
ATOM   1265 C  CG2 . VAL A 1 160 ? -11.36  -17.656 -6.275  1   27.83  ? 156 VAL A CG2 1 
ATOM   1266 N  N   . ARG A 1 161 ? -11.585 -13.757 -5.834  1   36.87  ? 157 ARG A N   1 
ATOM   1267 C  CA  . ARG A 1 161 ? -10.566 -12.813 -6.277  1   39.96  ? 157 ARG A CA  1 
ATOM   1268 C  C   . ARG A 1 161 ? -9.223  -13.341 -5.776  1   39.1   ? 157 ARG A C   1 
ATOM   1269 O  O   . ARG A 1 161 ? -9.183  -14.272 -4.958  1   34.14  ? 157 ARG A O   1 
ATOM   1270 C  CB  . ARG A 1 161 ? -10.738 -11.415 -5.654  1   41.93  ? 157 ARG A CB  1 
ATOM   1271 C  CG  . ARG A 1 161 ? -11.623 -10.412 -6.365  1   49.36  ? 157 ARG A CG  1 
ATOM   1272 C  CD  . ARG A 1 161 ? -11.775 -9.129  -5.567  1   56.35  ? 157 ARG A CD  1 
ATOM   1273 N  NE  . ARG A 1 161 ? -10.804 -9.036  -4.469  1   63.54  ? 157 ARG A NE  1 
ATOM   1274 C  CZ  . ARG A 1 161 ? -11.086 -8.607  -3.227  1   60.89  ? 157 ARG A CZ  1 
ATOM   1275 N  NH1 . ARG A 1 161 ? -12.287 -8.148  -2.919  1   56.33  ? 157 ARG A NH1 1 
ATOM   1276 N  NH2 . ARG A 1 161 ? -10.155 -8.608  -2.294  1   54.75  ? 157 ARG A NH2 1 
ATOM   1277 N  N   . THR A 1 162 ? -8.138  -12.719 -6.266  1   38.59  ? 158 THR A N   1 
ATOM   1278 C  CA  . THR A 1 162 ? -6.814  -13.007 -5.757  1   37.78  ? 158 THR A CA  1 
ATOM   1279 C  C   . THR A 1 162 ? -6.796  -12.493 -4.327  1   36.95  ? 158 THR A C   1 
ATOM   1280 O  O   . THR A 1 162 ? -7.128  -11.343 -4.098  1   38.89  ? 158 THR A O   1 
ATOM   1281 C  CB  . THR A 1 162 ? -5.761  -12.321 -6.637  1   40.99  ? 158 THR A CB  1 
ATOM   1282 O  OG1 . THR A 1 162 ? -5.923  -12.932 -7.915  1   44.85  ? 158 THR A OG1 1 
ATOM   1283 C  CG2 . THR A 1 162 ? -4.334  -12.496 -6.131  1   37.63  ? 158 THR A CG2 1 
ATOM   1284 N  N   . TYR A 1 163 ? -6.432  -13.354 -3.379  1   36.57  ? 159 TYR A N   1 
ATOM   1285 C  CA  . TYR A 1 163 ? -6.272  -12.918 -2.002  1   37.15  ? 159 TYR A CA  1 
ATOM   1286 C  C   . TYR A 1 163 ? -4.8    -13.063 -1.644  1   36.46  ? 159 TYR A C   1 
ATOM   1287 O  O   . TYR A 1 163 ? -3.97   -13.347 -2.507  1   32.84  ? 159 TYR A O   1 
ATOM   1288 C  CB  . TYR A 1 163 ? -7.162  -13.771 -1.084  1   37.4   ? 159 TYR A CB  1 
ATOM   1289 C  CG  . TYR A 1 163 ? -8.627  -13.797 -1.496  1   38.18  ? 159 TYR A CG  1 
ATOM   1290 C  CD1 . TYR A 1 163 ? -9.335  -12.621 -1.735  1   37.78  ? 159 TYR A CD1 1 
ATOM   1291 C  CD2 . TYR A 1 163 ? -9.289  -15.007 -1.689  1   38.76  ? 159 TYR A CD2 1 
ATOM   1292 C  CE1 . TYR A 1 163 ? -10.66  -12.665 -2.13   1   39.76  ? 159 TYR A CE1 1 
ATOM   1293 C  CE2 . TYR A 1 163 ? -10.615 -15.065 -2.078  1   35.81  ? 159 TYR A CE2 1 
ATOM   1294 C  CZ  . TYR A 1 163 ? -11.282 -13.889 -2.33   1   38.1   ? 159 TYR A CZ  1 
ATOM   1295 O  OH  . TYR A 1 163 ? -12.563 -13.961 -2.736  1   40.55  ? 159 TYR A OH  1 
HETATM 1296 N  N   . TPO A 1 164 ? -4.504  -12.923 -0.349  1   38.01  ? 160 TPO A N   1 
HETATM 1297 C  CA  . TPO A 1 164 ? -3.147  -13.079 0.143   1   40.13  ? 160 TPO A CA  1 
HETATM 1298 C  CB  . TPO A 1 164 ? -3.148  -12.849 1.656   1   41.28  ? 160 TPO A CB  1 
HETATM 1299 C  CG2 . TPO A 1 164 ? -1.754  -12.753 2.233   1   38.16  ? 160 TPO A CG2 1 
HETATM 1300 O  OG1 . TPO A 1 164 ? -3.841  -11.562 1.852   1   42     ? 160 TPO A OG1 1 
HETATM 1301 P  P   . TPO A 1 164 ? -5.237  -11.601 2.664   1   38.65  ? 160 TPO A P   1 
HETATM 1302 O  O1P . TPO A 1 164 ? -6.178  -12.466 1.852   1   38.24  ? 160 TPO A O1P 1 
HETATM 1303 O  O2P . TPO A 1 164 ? -5.631  -10.15  2.754   1   39.8   ? 160 TPO A O2P 1 
HETATM 1304 O  O3P . TPO A 1 164 ? -4.982  -12.246 4.018   1   38.21  ? 160 TPO A O3P 1 
HETATM 1305 C  C   . TPO A 1 164 ? -2.546  -14.434 -0.257  1   39.66  ? 160 TPO A C   1 
HETATM 1306 O  O   . TPO A 1 164 ? -3.177  -15.491 -0.131  1   36.61  ? 160 TPO A O   1 
ATOM   1307 N  N   . HIS A 1 165 ? -1.28   -14.369 -0.678  1   38.69  ? 161 HIS A N   1 
ATOM   1308 C  CA  . HIS A 1 165 ? -0.471  -15.506 -1.081  1   44.81  ? 161 HIS A CA  1 
ATOM   1309 C  C   . HIS A 1 165 ? 0.251   -16.17  0.103   1   47.05  ? 161 HIS A C   1 
ATOM   1310 O  O   . HIS A 1 165 ? 0.455   -17.385 0.113   1   45.23  ? 161 HIS A O   1 
ATOM   1311 C  CB  . HIS A 1 165 ? 0.554   -15.046 -2.117  1   45.79  ? 161 HIS A CB  1 
ATOM   1312 C  CG  . HIS A 1 165 ? 1.587   -16.082 -2.419  1   55.78  ? 161 HIS A CG  1 
ATOM   1313 N  ND1 . HIS A 1 165 ? 1.269   -17.346 -2.868  1   51.27  ? 161 HIS A ND1 1 
ATOM   1314 C  CD2 . HIS A 1 165 ? 2.942   -16.025 -2.379  1   61.53  ? 161 HIS A CD2 1 
ATOM   1315 C  CE1 . HIS A 1 165 ? 2.394   -18.01  -3.099  1   56.1   ? 161 HIS A CE1 1 
ATOM   1316 N  NE2 . HIS A 1 165 ? 3.421   -17.235 -2.807  1   60.45  ? 161 HIS A NE2 1 
ATOM   1317 N  N   . GLU A 1 166 ? 0.673   -15.37  1.092   1   50.21  ? 162 GLU A N   1 
ATOM   1318 C  CA  . GLU A 1 166 ? 1.367   -15.875 2.276   1   56.91  ? 162 GLU A CA  1 
ATOM   1319 C  C   . GLU A 1 166 ? 0.32    -16.444 3.233   1   57.13  ? 162 GLU A C   1 
ATOM   1320 O  O   . GLU A 1 166 ? 0.003   -15.789 4.242   1   51.29  ? 162 GLU A O   1 
ATOM   1321 C  CB  . GLU A 1 166 ? 2.123   -14.783 3.052   1   63.34  ? 162 GLU A CB  1 
ATOM   1322 C  CG  . GLU A 1 166 ? 3.103   -13.944 2.22    1   76.68  ? 162 GLU A CG  1 
ATOM   1323 C  CD  . GLU A 1 166 ? 2.627   -13.207 0.954   1   82.95  ? 162 GLU A CD  1 
ATOM   1324 O  OE1 . GLU A 1 166 ? 1.603   -12.493 1.088   1   87.83  ? 162 GLU A OE1 1 
ATOM   1325 O  OE2 . GLU A 1 166 ? 3.243   -13.298 -0.155  1   71.32  ? 162 GLU A OE2 1 
ATOM   1326 N  N   . VAL A 1 167 ? -0.227  -17.63  2.877   1   49.22  ? 163 VAL A N   1 
ATOM   1327 C  CA  . VAL A 1 167 ? -1.313  -18.258 3.629   1   43.75  ? 163 VAL A CA  1 
ATOM   1328 C  C   . VAL A 1 167 ? -1.011  -19.739 3.863   1   38.92  ? 163 VAL A C   1 
ATOM   1329 O  O   . VAL A 1 167 ? -0.448  -20.389 2.985   1   35.95  ? 163 VAL A O   1 
ATOM   1330 C  CB  . VAL A 1 167 ? -2.723  -18.112 3.015   1   41.65  ? 163 VAL A CB  1 
ATOM   1331 C  CG1 . VAL A 1 167 ? -3.226  -16.674 3.041   1   43.6   ? 163 VAL A CG1 1 
ATOM   1332 C  CG2 . VAL A 1 167 ? -2.844  -18.743 1.632   1   38.08  ? 163 VAL A CG2 1 
ATOM   1333 N  N   . VAL A 1 168 ? -1.455  -20.249 5.029   1   34.28  ? 164 VAL A N   1 
ATOM   1334 C  CA  . VAL A 1 168 ? -1.425  -21.652 5.425   1   31.65  ? 164 VAL A CA  1 
ATOM   1335 C  C   . VAL A 1 168 ? -0.018  -22.004 5.892   1   33.72  ? 164 VAL A C   1 
ATOM   1336 O  O   . VAL A 1 168 ? 0.952   -21.747 5.173   1   33.29  ? 164 VAL A O   1 
ATOM   1337 C  CB  . VAL A 1 168 ? -1.92   -22.667 4.378   1   30.11  ? 164 VAL A CB  1 
ATOM   1338 C  CG1 . VAL A 1 168 ? -2.205  -24.018 5.028   1   31.53  ? 164 VAL A CG1 1 
ATOM   1339 C  CG2 . VAL A 1 168 ? -3.162  -22.165 3.651   1   28.19  ? 164 VAL A CG2 1 
ATOM   1340 N  N   . THR A 1 169 ? 0.086   -22.57  7.109   1   32.28  ? 165 THR A N   1 
ATOM   1341 C  CA  . THR A 1 169 ? 1.368   -23.052 7.598   1   30.69  ? 165 THR A CA  1 
ATOM   1342 C  C   . THR A 1 169 ? 1.892   -24.054 6.562   1   32.08  ? 165 THR A C   1 
ATOM   1343 O  O   . THR A 1 169 ? 1.14    -24.867 6.017   1   32.04  ? 165 THR A O   1 
ATOM   1344 C  CB  . THR A 1 169 ? 1.18    -23.678 8.983   1   30.59  ? 165 THR A CB  1 
ATOM   1345 O  OG1 . THR A 1 169 ? 0.583   -22.703 9.833   1   30.05  ? 165 THR A OG1 1 
ATOM   1346 C  CG2 . THR A 1 169 ? 2.478   -24.181 9.597   1   29.13  ? 165 THR A CG2 1 
ATOM   1347 N  N   . LEU A 1 170 ? 3.196   -23.989 6.302   1   32.64  ? 166 LEU A N   1 
ATOM   1348 C  CA  . LEU A 1 170 ? 3.816   -24.615 5.149   1   34.03  ? 166 LEU A CA  1 
ATOM   1349 C  C   . LEU A 1 170 ? 3.456   -26.095 5.034   1   34.34  ? 166 LEU A C   1 
ATOM   1350 O  O   . LEU A 1 170 ? 3.115   -26.545 3.942   1   33.22  ? 166 LEU A O   1 
ATOM   1351 C  CB  . LEU A 1 170 ? 5.33    -24.421 5.244   1   35.85  ? 166 LEU A CB  1 
ATOM   1352 C  CG  . LEU A 1 170 ? 6.185   -25.013 4.117   1   34.18  ? 166 LEU A CG  1 
ATOM   1353 C  CD1 . LEU A 1 170 ? 5.727   -24.43  2.766   1   31.4   ? 166 LEU A CD1 1 
ATOM   1354 C  CD2 . LEU A 1 170 ? 7.637   -24.669 4.46    1   31.41  ? 166 LEU A CD2 1 
ATOM   1355 N  N   . TRP A 1 171 ? 3.567   -26.85  6.14    1   33.58  ? 167 TRP A N   1 
ATOM   1356 C  CA  . TRP A 1 171 ? 3.291   -28.28  6.065   1   31.89  ? 167 TRP A CA  1 
ATOM   1357 C  C   . TRP A 1 171 ? 1.891   -28.561 5.49    1   30.52  ? 167 TRP A C   1 
ATOM   1358 O  O   . TRP A 1 171 ? 1.666   -29.679 5.033   1   28.27  ? 167 TRP A O   1 
ATOM   1359 C  CB  . TRP A 1 171 ? 3.49    -28.971 7.426   1   31.03  ? 167 TRP A CB  1 
ATOM   1360 C  CG  . TRP A 1 171 ? 4.918   -28.969 7.899   1   33.9   ? 167 TRP A CG  1 
ATOM   1361 C  CD1 . TRP A 1 171 ? 5.999   -28.512 7.205   1   35.59  ? 167 TRP A CD1 1 
ATOM   1362 C  CD2 . TRP A 1 171 ? 5.431   -29.448 9.16    1   34.22  ? 167 TRP A CD2 1 
ATOM   1363 N  NE1 . TRP A 1 171 ? 7.144   -28.686 7.935   1   36.04  ? 167 TRP A NE1 1 
ATOM   1364 C  CE2 . TRP A 1 171 ? 6.829   -29.242 9.137   1   34.81  ? 167 TRP A CE2 1 
ATOM   1365 C  CE3 . TRP A 1 171 ? 4.849   -30.01  10.305  1   34.61  ? 167 TRP A CE3 1 
ATOM   1366 C  CZ2 . TRP A 1 171 ? 7.649   -29.572 10.208  1   36.46  ? 167 TRP A CZ2 1 
ATOM   1367 C  CZ3 . TRP A 1 171 ? 5.66    -30.326 11.376  1   35.17  ? 167 TRP A CZ3 1 
ATOM   1368 C  CH2 . TRP A 1 171 ? 7.034   -30.09  11.333  1   37.09  ? 167 TRP A CH2 1 
ATOM   1369 N  N   . TYR A 1 172 ? 0.963   -27.572 5.526   1   27.05  ? 168 TYR A N   1 
ATOM   1370 C  CA  . TYR A 1 172 ? -0.458  -27.83  5.301   1   27.63  ? 168 TYR A CA  1 
ATOM   1371 C  C   . TYR A 1 172 ? -0.926  -27.103 4.04    1   29.98  ? 168 TYR A C   1 
ATOM   1372 O  O   . TYR A 1 172 ? -2.114  -27.142 3.688   1   28.07  ? 168 TYR A O   1 
ATOM   1373 C  CB  . TYR A 1 172 ? -1.33   -27.529 6.537   1   26.5   ? 168 TYR A CB  1 
ATOM   1374 C  CG  . TYR A 1 172 ? -0.828  -28.291 7.751   1   25.68  ? 168 TYR A CG  1 
ATOM   1375 C  CD1 . TYR A 1 172 ? -1.262  -29.585 8.008   1   24.92  ? 168 TYR A CD1 1 
ATOM   1376 C  CD2 . TYR A 1 172 ? 0.165   -27.75  8.576   1   27.15  ? 168 TYR A CD2 1 
ATOM   1377 C  CE1 . TYR A 1 172 ? -0.747  -30.318 9.07    1   25.98  ? 168 TYR A CE1 1 
ATOM   1378 C  CE2 . TYR A 1 172 ? 0.669   -28.46  9.65    1   26.51  ? 168 TYR A CE2 1 
ATOM   1379 C  CZ  . TYR A 1 172 ? 0.193   -29.736 9.901   1   25.62  ? 168 TYR A CZ  1 
ATOM   1380 O  OH  . TYR A 1 172 ? 0.716   -30.451 10.915  1   25.09  ? 168 TYR A OH  1 
ATOM   1381 N  N   . ARG A 1 173 ? 0.034   -26.457 3.361   1   31.27  ? 169 ARG A N   1 
ATOM   1382 C  CA  . ARG A 1 173 ? -0.251  -25.572 2.238   1   30.51  ? 169 ARG A CA  1 
ATOM   1383 C  C   . ARG A 1 173 ? -0.47   -26.383 0.956   1   30.89  ? 169 ARG A C   1 
ATOM   1384 O  O   . ARG A 1 173 ? 0.378   -27.182 0.576   1   30.71  ? 169 ARG A O   1 
ATOM   1385 C  CB  . ARG A 1 173 ? 0.895   -24.564 2.092   1   28.39  ? 169 ARG A CB  1 
ATOM   1386 C  CG  . ARG A 1 173 ? 0.592   -23.523 1.022   1   28.91  ? 169 ARG A CG  1 
ATOM   1387 C  CD  . ARG A 1 173 ? 1.677   -22.455 0.938   1   28.79  ? 169 ARG A CD  1 
ATOM   1388 N  NE  . ARG A 1 173 ? 2.024   -22.048 2.302   1   28.95  ? 169 ARG A NE  1 
ATOM   1389 C  CZ  . ARG A 1 173 ? 3.09    -21.353 2.641   1   32.53  ? 169 ARG A CZ  1 
ATOM   1390 N  NH1 . ARG A 1 173 ? 3.992   -20.998 1.74    1   34.22  ? 169 ARG A NH1 1 
ATOM   1391 N  NH2 . ARG A 1 173 ? 3.278   -21.05  3.904   1   32.85  ? 169 ARG A NH2 1 
ATOM   1392 N  N   . ALA A 1 174 ? -1.595  -26.112 0.284   1   28.13  ? 170 ALA A N   1 
ATOM   1393 C  CA  . ALA A 1 174 ? -2.004  -26.706 -0.973  1   26.72  ? 170 ALA A CA  1 
ATOM   1394 C  C   . ALA A 1 174 ? -1.055  -26.346 -2.116  1   28.64  ? 170 ALA A C   1 
ATOM   1395 O  O   . ALA A 1 174 ? -0.51   -25.241 -2.173  1   31.45  ? 170 ALA A O   1 
ATOM   1396 C  CB  . ALA A 1 174 ? -3.409  -26.228 -1.266  1   26.13  ? 170 ALA A CB  1 
ATOM   1397 N  N   . PRO A 1 175 ? -0.859  -27.254 -3.092  1   27.1   ? 171 PRO A N   1 
ATOM   1398 C  CA  . PRO A 1 175 ? 0.067   -27.014 -4.201  1   30.78  ? 171 PRO A CA  1 
ATOM   1399 C  C   . PRO A 1 175 ? -0.25   -25.803 -5.084  1   31.55  ? 171 PRO A C   1 
ATOM   1400 O  O   . PRO A 1 175 ? 0.634   -25.166 -5.666  1   34.99  ? 171 PRO A O   1 
ATOM   1401 C  CB  . PRO A 1 175 ? 0.109   -28.362 -4.995  1   28.84  ? 171 PRO A CB  1 
ATOM   1402 C  CG  . PRO A 1 175 ? -1.153  -29.066 -4.596  1   29.13  ? 171 PRO A CG  1 
ATOM   1403 C  CD  . PRO A 1 175 ? -1.516  -28.558 -3.185  1   27.65  ? 171 PRO A CD  1 
ATOM   1404 N  N   . GLU A 1 176 ? -1.527  -25.477 -5.193  1   31.22  ? 172 GLU A N   1 
ATOM   1405 C  CA  . GLU A 1 176 ? -1.877  -24.348 -6.034  1   32.85  ? 172 GLU A CA  1 
ATOM   1406 C  C   . GLU A 1 176 ? -1.34   -23.069 -5.402  1   33.14  ? 172 GLU A C   1 
ATOM   1407 O  O   . GLU A 1 176 ? -1.15   -22.103 -6.126  1   37.12  ? 172 GLU A O   1 
ATOM   1408 C  CB  . GLU A 1 176 ? -3.377  -24.257 -6.353  1   31.43  ? 172 GLU A CB  1 
ATOM   1409 C  CG  . GLU A 1 176 ? -4.274  -24.182 -5.117  1   31.47  ? 172 GLU A CG  1 
ATOM   1410 C  CD  . GLU A 1 176 ? -4.825  -25.468 -4.524  1   32.86  ? 172 GLU A CD  1 
ATOM   1411 O  OE1 . GLU A 1 176 ? -5.987  -25.406 -4.023  1   29.18  ? 172 GLU A OE1 1 
ATOM   1412 O  OE2 . GLU A 1 176 ? -4.111  -26.522 -4.579  1   31.5   ? 172 GLU A OE2 1 
ATOM   1413 N  N   . ILE A 1 177 ? -1.146  -23.046 -4.068  1   30.76  ? 173 ILE A N   1 
ATOM   1414 C  CA  . ILE A 1 177 ? -0.547  -21.88  -3.416  1   31.98  ? 173 ILE A CA  1 
ATOM   1415 C  C   . ILE A 1 177 ? 0.967   -21.906 -3.649  1   33.8   ? 173 ILE A C   1 
ATOM   1416 O  O   . ILE A 1 177 ? 1.561   -20.94  -4.124  1   34.76  ? 173 ILE A O   1 
ATOM   1417 C  CB  . ILE A 1 177 ? -0.901  -21.819 -1.914  1   32.42  ? 173 ILE A CB  1 
ATOM   1418 C  CG1 . ILE A 1 177 ? -2.423  -21.781 -1.682  1   31.17  ? 173 ILE A CG1 1 
ATOM   1419 C  CG2 . ILE A 1 177 ? -0.194  -20.661 -1.207  1   29.3   ? 173 ILE A CG2 1 
ATOM   1420 C  CD1 . ILE A 1 177 ? -2.834  -22.082 -0.26   1   28.32  ? 173 ILE A CD1 1 
ATOM   1421 N  N   . LEU A 1 178 ? 1.604   -23.04  -3.352  1   31.27  ? 174 LEU A N   1 
ATOM   1422 C  CA  . LEU A 1 178 ? 3.025   -23.146 -3.622  1   31.51  ? 174 LEU A CA  1 
ATOM   1423 C  C   . LEU A 1 178 ? 3.365   -22.75  -5.057  1   34.11  ? 174 LEU A C   1 
ATOM   1424 O  O   . LEU A 1 178 ? 4.429   -22.141 -5.253  1   34.98  ? 174 LEU A O   1 
ATOM   1425 C  CB  . LEU A 1 178 ? 3.51    -24.536 -3.246  1   30.18  ? 174 LEU A CB  1 
ATOM   1426 C  CG  . LEU A 1 178 ? 3.382   -24.847 -1.75   1   28.31  ? 174 LEU A CG  1 
ATOM   1427 C  CD1 . LEU A 1 178 ? 3.174   -26.343 -1.525  1   26.15  ? 174 LEU A CD1 1 
ATOM   1428 C  CD2 . LEU A 1 178 ? 4.632   -24.324 -1.059  1   27.92  ? 174 LEU A CD2 1 
ATOM   1429 N  N   . LEU A 1 179 ? 2.465   -23.034 -6.03   1   32.68  ? 175 LEU A N   1 
ATOM   1430 C  CA  . LEU A 1 179 ? 2.749   -22.744 -7.44   1   34.97  ? 175 LEU A CA  1 
ATOM   1431 C  C   . LEU A 1 179 ? 2.31    -21.328 -7.829  1   37.08  ? 175 LEU A C   1 
ATOM   1432 O  O   . LEU A 1 179 ? 2.297   -20.975 -9.012  1   38.49  ? 175 LEU A O   1 
ATOM   1433 C  CB  . LEU A 1 179 ? 2.171   -23.764 -8.422  1   32.03  ? 175 LEU A CB  1 
ATOM   1434 C  CG  . LEU A 1 179 ? 2.737   -25.176 -8.325  1   31.03  ? 175 LEU A CG  1 
ATOM   1435 C  CD1 . LEU A 1 179 ? 1.774   -26.106 -9.022  1   29.57  ? 175 LEU A CD1 1 
ATOM   1436 C  CD2 . LEU A 1 179 ? 4.131   -25.204 -8.926  1   29.78  ? 175 LEU A CD2 1 
ATOM   1437 N  N   . GLY A 1 180 ? 1.935   -20.523 -6.83   1   37.66  ? 176 GLY A N   1 
ATOM   1438 C  CA  . GLY A 1 180 ? 1.712   -19.103 -7.034  1   36.54  ? 176 GLY A CA  1 
ATOM   1439 C  C   . GLY A 1 180 ? 0.506   -18.861 -7.929  1   38.69  ? 176 GLY A C   1 
ATOM   1440 O  O   . GLY A 1 180 ? 0.502   -17.94  -8.741  1   41.89  ? 176 GLY A O   1 
ATOM   1441 N  N   . CYS A 1 181 ? -0.515  -19.706 -7.784  1   39.66  ? 177 CYS A N   1 
ATOM   1442 C  CA  . CYS A 1 181 ? -1.724  -19.578 -8.595  1   43.39  ? 177 CYS A CA  1 
ATOM   1443 C  C   . CYS A 1 181 ? -2.401  -18.24  -8.281  1   41.08  ? 177 CYS A C   1 
ATOM   1444 O  O   . CYS A 1 181 ? -2.44   -17.796 -7.119  1   38.36  ? 177 CYS A O   1 
ATOM   1445 C  CB  . CYS A 1 181 ? -2.603  -20.836 -8.539  1   45.68  ? 177 CYS A CB  1 
ATOM   1446 S  SG  . CYS A 1 181 ? -2.045  -22.182 -9.642  1   53.95  ? 177 CYS A SG  1 
ATOM   1447 N  N   . LYS A 1 182 ? -2.879  -17.585 -9.348  1   37.9   ? 178 LYS A N   1 
ATOM   1448 C  CA  . LYS A 1 182 ? -3.584  -16.324 -9.204  1   38.19  ? 178 LYS A CA  1 
ATOM   1449 C  C   . LYS A 1 182 ? -4.789  -16.472 -8.252  1   35.62  ? 178 LYS A C   1 
ATOM   1450 O  O   . LYS A 1 182 ? -5.089  -15.572 -7.463  1   32.08  ? 178 LYS A O   1 
ATOM   1451 C  CB  . LYS A 1 182 ? -3.892  -15.895 -10.636 1   39.67  ? 178 LYS A CB  1 
ATOM   1452 C  CG  . LYS A 1 182 ? -4.749  -14.665 -10.746 1   48.66  ? 178 LYS A CG  1 
ATOM   1453 C  CD  . LYS A 1 182 ? -4.978  -14.22  -12.191 1   59.28  ? 178 LYS A CD  1 
ATOM   1454 C  CE  . LYS A 1 182 ? -5.783  -12.954 -12.2   1   69.7   ? 178 LYS A CE  1 
ATOM   1455 N  NZ  . LYS A 1 182 ? -6.076  -12.46  -13.547 1   83.97  ? 178 LYS A NZ  1 
ATOM   1456 N  N   . TYR A 1 183 ? -5.471  -17.608 -8.369  1   34.58  ? 179 TYR A N   1 
ATOM   1457 C  CA  . TYR A 1 183 ? -6.71   -17.816 -7.586  1   34.64  ? 179 TYR A CA  1 
ATOM   1458 C  C   . TYR A 1 183 ? -6.651  -19.094 -6.801  1   33.36  ? 179 TYR A C   1 
ATOM   1459 O  O   . TYR A 1 183 ? -6.118  -20.099 -7.287  1   32.29  ? 179 TYR A O   1 
ATOM   1460 C  CB  . TYR A 1 183 ? -7.916  -17.899 -8.521  1   35.67  ? 179 TYR A CB  1 
ATOM   1461 C  CG  . TYR A 1 183 ? -8.243  -16.656 -9.331  1   38.34  ? 179 TYR A CG  1 
ATOM   1462 C  CD1 . TYR A 1 183 ? -8.538  -15.448 -8.714  1   38.26  ? 179 TYR A CD1 1 
ATOM   1463 C  CD2 . TYR A 1 183 ? -8.277  -16.704 -10.716 1   37.56  ? 179 TYR A CD2 1 
ATOM   1464 C  CE1 . TYR A 1 183 ? -8.846  -14.321 -9.455  1   41.17  ? 179 TYR A CE1 1 
ATOM   1465 C  CE2 . TYR A 1 183 ? -8.584  -15.585 -11.468 1   40.28  ? 179 TYR A CE2 1 
ATOM   1466 C  CZ  . TYR A 1 183 ? -8.871  -14.392 -10.835 1   44.4   ? 179 TYR A CZ  1 
ATOM   1467 O  OH  . TYR A 1 183 ? -9.173  -13.297 -11.587 1   45.38  ? 179 TYR A OH  1 
ATOM   1468 N  N   . TYR A 1 184 ? -7.188  -19.039 -5.591  1   31.79  ? 180 TYR A N   1 
ATOM   1469 C  CA  . TYR A 1 184 ? -7.302  -20.244 -4.743  1   31.51  ? 180 TYR A CA  1 
ATOM   1470 C  C   . TYR A 1 184 ? -8.686  -20.177 -4.096  1   33.6   ? 180 TYR A C   1 
ATOM   1471 O  O   . TYR A 1 184 ? -9.22   -19.079 -3.904  1   34.46  ? 180 TYR A O   1 
ATOM   1472 C  CB  . TYR A 1 184 ? -6.117  -20.348 -3.779  1   31.32  ? 180 TYR A CB  1 
ATOM   1473 C  CG  . TYR A 1 184 ? -5.962  -19.302 -2.691  1   29.72  ? 180 TYR A CG  1 
ATOM   1474 C  CD1 . TYR A 1 184 ? -6.78   -19.298 -1.571  1   27.8   ? 180 TYR A CD1 1 
ATOM   1475 C  CD2 . TYR A 1 184 ? -4.958  -18.351 -2.769  1   31.39  ? 180 TYR A CD2 1 
ATOM   1476 C  CE1 . TYR A 1 184 ? -6.627  -18.35  -0.576  1   31     ? 180 TYR A CE1 1 
ATOM   1477 C  CE2 . TYR A 1 184 ? -4.796  -17.397 -1.783  1   31.39  ? 180 TYR A CE2 1 
ATOM   1478 C  CZ  . TYR A 1 184 ? -5.633  -17.398 -0.684  1   32.34  ? 180 TYR A CZ  1 
ATOM   1479 O  OH  . TYR A 1 184 ? -5.473  -16.465 0.289   1   34.67  ? 180 TYR A OH  1 
ATOM   1480 N  N   . SER A 1 185 ? -9.249  -21.334 -3.773  1   31.96  ? 181 SER A N   1 
ATOM   1481 C  CA  . SER A 1 185 ? -10.612 -21.359 -3.199  1   28.93  ? 181 SER A CA  1 
ATOM   1482 C  C   . SER A 1 185 ? -10.702 -22.264 -1.972  1   26.53  ? 181 SER A C   1 
ATOM   1483 O  O   . SER A 1 185 ? -9.723  -22.363 -1.246  1   29.19  ? 181 SER A O   1 
ATOM   1484 C  CB  . SER A 1 185 ? -11.623 -21.771 -4.226  1   30.08  ? 181 SER A CB  1 
ATOM   1485 O  OG  . SER A 1 185 ? -12.93  -21.357 -3.863  1   31.99  ? 181 SER A OG  1 
ATOM   1486 N  N   . THR A 1 186 ? -11.833 -22.924 -1.803  1   26.77  ? 182 THR A N   1 
ATOM   1487 C  CA  . THR A 1 186 ? -12.133 -23.732 -0.615  1   26.89  ? 182 THR A CA  1 
ATOM   1488 C  C   . THR A 1 186 ? -11.342 -25.006 -0.592  1   29.06  ? 182 THR A C   1 
ATOM   1489 O  O   . THR A 1 186 ? -11.293 -25.631 0.47    1   29.7   ? 182 THR A O   1 
ATOM   1490 C  CB  . THR A 1 186 ? -13.634 -23.986 -0.719  1   28.65  ? 182 THR A CB  1 
ATOM   1491 O  OG1 . THR A 1 186 ? -13.863 -24.472 -2.036  1   29.86  ? 182 THR A OG1 1 
ATOM   1492 C  CG2 . THR A 1 186 ? -14.46  -22.732 -0.509  1   23.79  ? 182 THR A CG2 1 
ATOM   1493 N  N   . ALA A 1 187 ? -10.72  -25.359 -1.712  1   31.05  ? 183 ALA A N   1 
ATOM   1494 C  CA  . ALA A 1 187 ? -9.975  -26.627 -1.837  1   26.72  ? 183 ALA A CA  1 
ATOM   1495 C  C   . ALA A 1 187 ? -8.679  -26.558 -1.038  1   27.38  ? 183 ALA A C   1 
ATOM   1496 O  O   . ALA A 1 187 ? -8.144  -27.603 -0.675  1   27.83  ? 183 ALA A O   1 
ATOM   1497 C  CB  . ALA A 1 187 ? -9.723  -26.88  -3.296  1   25.41  ? 183 ALA A CB  1 
ATOM   1498 N  N   . VAL A 1 188 ? -8.215  -25.348 -0.761  1   26.98  ? 184 VAL A N   1 
ATOM   1499 C  CA  . VAL A 1 188 ? -6.971  -25.171 0.038   1   29.21  ? 184 VAL A CA  1 
ATOM   1500 C  C   . VAL A 1 188 ? -7.249  -25.669 1.464   1   27.66  ? 184 VAL A C   1 
ATOM   1501 O  O   . VAL A 1 188 ? -6.329  -26.208 2.08    1   29.94  ? 184 VAL A O   1 
ATOM   1502 C  CB  . VAL A 1 188 ? -6.428  -23.725 -0.005  1   28.42  ? 184 VAL A CB  1 
ATOM   1503 C  CG1 . VAL A 1 188 ? -6.447  -23.148 -1.411  1   29.4   ? 184 VAL A CG1 1 
ATOM   1504 C  CG2 . VAL A 1 188 ? -7.1    -22.791 0.992   1   27.61  ? 184 VAL A CG2 1 
ATOM   1505 N  N   . ASP A 1 189 ? -8.487  -25.524 1.932   1   28.62  ? 185 ASP A N   1 
ATOM   1506 C  CA  . ASP A 1 189 ? -8.801  -25.945 3.288   1   30.07  ? 185 ASP A CA  1 
ATOM   1507 C  C   . ASP A 1 189 ? -8.943  -27.452 3.282   1   28.2   ? 185 ASP A C   1 
ATOM   1508 O  O   . ASP A 1 189 ? -8.565  -28.107 4.235   1   29.36  ? 185 ASP A O   1 
ATOM   1509 C  CB  . ASP A 1 189 ? -10.033 -25.245 3.859   1   30.59  ? 185 ASP A CB  1 
ATOM   1510 C  CG  . ASP A 1 189 ? -9.811  -23.789 4.248   1   32.01  ? 185 ASP A CG  1 
ATOM   1511 O  OD1 . ASP A 1 189 ? -8.625  -23.445 4.49    1   30.42  ? 185 ASP A OD1 1 
ATOM   1512 O  OD2 . ASP A 1 189 ? -10.807 -23.012 4.254   1   29.85  ? 185 ASP A OD2 1 
ATOM   1513 N  N   . ILE A 1 190 ? -9.493  -27.988 2.194   1   30.91  ? 186 ILE A N   1 
ATOM   1514 C  CA  . ILE A 1 190 ? -9.668  -29.427 2.124   1   32.01  ? 186 ILE A CA  1 
ATOM   1515 C  C   . ILE A 1 190 ? -8.286  -30.067 2.103   1   32.24  ? 186 ILE A C   1 
ATOM   1516 O  O   . ILE A 1 190 ? -8.034  -31.032 2.819   1   32.74  ? 186 ILE A O   1 
ATOM   1517 C  CB  . ILE A 1 190 ? -10.555 -29.865 0.94    1   31.2   ? 186 ILE A CB  1 
ATOM   1518 C  CG1 . ILE A 1 190 ? -12.021 -29.533 1.212   1   26.47  ? 186 ILE A CG1 1 
ATOM   1519 C  CG2 . ILE A 1 190 ? -10.392 -31.365 0.68    1   29.15  ? 186 ILE A CG2 1 
ATOM   1520 C  CD1 . ILE A 1 190 ? -12.62  -30.291 2.388   1   25.47  ? 186 ILE A CD1 1 
ATOM   1521 N  N   . TRP A 1 191 ? -7.37   -29.478 1.326   1   32.37  ? 187 TRP A N   1 
ATOM   1522 C  CA  . TRP A 1 191 ? -6.004  -29.978 1.305   1   28.86  ? 187 TRP A CA  1 
ATOM   1523 C  C   . TRP A 1 191 ? -5.452  -30.064 2.726   1   29.06  ? 187 TRP A C   1 
ATOM   1524 O  O   . TRP A 1 191 ? -4.986  -31.112 3.139   1   31.78  ? 187 TRP A O   1 
ATOM   1525 C  CB  . TRP A 1 191 ? -5.12   -29.114 0.401   1   27.79  ? 187 TRP A CB  1 
ATOM   1526 C  CG  . TRP A 1 191 ? -3.707  -29.628 0.357   1   31.26  ? 187 TRP A CG  1 
ATOM   1527 C  CD1 . TRP A 1 191 ? -2.702  -29.352 1.243   1   29.34  ? 187 TRP A CD1 1 
ATOM   1528 C  CD2 . TRP A 1 191 ? -3.141  -30.511 -0.645  1   29.79  ? 187 TRP A CD2 1 
ATOM   1529 N  NE1 . TRP A 1 191 ? -1.553  -30.006 0.87    1   30.73  ? 187 TRP A NE1 1 
ATOM   1530 C  CE2 . TRP A 1 191 ? -1.79   -30.715 -0.282  1   30.45  ? 187 TRP A CE2 1 
ATOM   1531 C  CE3 . TRP A 1 191 ? -3.633  -31.132 -1.796  1   27.12  ? 187 TRP A CE3 1 
ATOM   1532 C  CZ2 . TRP A 1 191 ? -0.943  -31.512 -1.049  1   31.2   ? 187 TRP A CZ2 1 
ATOM   1533 C  CZ3 . TRP A 1 191 ? -2.787  -31.911 -2.552  1   28.71  ? 187 TRP A CZ3 1 
ATOM   1534 C  CH2 . TRP A 1 191 ? -1.458  -32.108 -2.182  1   28.63  ? 187 TRP A CH2 1 
ATOM   1535 N  N   . SER A 1 192 ? -5.554  -28.974 3.493   1   30.6   ? 188 SER A N   1 
ATOM   1536 C  CA  . SER A 1 192 ? -5.134  -28.961 4.894   1   31.04  ? 188 SER A CA  1 
ATOM   1537 C  C   . SER A 1 192 ? -5.735  -30.129 5.679   1   30.14  ? 188 SER A C   1 
ATOM   1538 O  O   . SER A 1 192 ? -5.014  -30.875 6.314   1   30.08  ? 188 SER A O   1 
ATOM   1539 C  CB  . SER A 1 192 ? -5.4    -27.624 5.562   1   28.48  ? 188 SER A CB  1 
ATOM   1540 O  OG  . SER A 1 192 ? -4.683  -26.599 4.885   1   28.92  ? 188 SER A OG  1 
ATOM   1541 N  N   . LEU A 1 193 ? -7.057  -30.325 5.595   1   32.73  ? 189 LEU A N   1 
ATOM   1542 C  CA  . LEU A 1 193 ? -7.722  -31.394 6.328   1   29.72  ? 189 LEU A CA  1 
ATOM   1543 C  C   . LEU A 1 193 ? -7.195  -32.761 5.895   1   31.85  ? 189 LEU A C   1 
ATOM   1544 O  O   . LEU A 1 193 ? -7.096  -33.67  6.73    1   33.11  ? 189 LEU A O   1 
ATOM   1545 C  CB  . LEU A 1 193 ? -9.236  -31.344 6.156   1   28.75  ? 189 LEU A CB  1 
ATOM   1546 C  CG  . LEU A 1 193 ? -9.986  -30.26  6.933   1   28.79  ? 189 LEU A CG  1 
ATOM   1547 C  CD1 . LEU A 1 193 ? -11.486 -30.658 6.916   1   24.49  ? 189 LEU A CD1 1 
ATOM   1548 C  CD2 . LEU A 1 193 ? -9.367  -30.094 8.344   1   25.85  ? 189 LEU A CD2 1 
ATOM   1549 N  N   . GLY A 1 194 ? -6.897  -32.91  4.592   1   28.04  ? 190 GLY A N   1 
ATOM   1550 C  CA  . GLY A 1 194 ? -6.266  -34.122 4.089   1   27.59  ? 190 GLY A CA  1 
ATOM   1551 C  C   . GLY A 1 194 ? -4.947  -34.398 4.821   1   28.44  ? 190 GLY A C   1 
ATOM   1552 O  O   . GLY A 1 194 ? -4.726  -35.481 5.36    1   27.35  ? 190 GLY A O   1 
ATOM   1553 N  N   . CYS A 1 195 ? -4.064  -33.397 4.857   1   27.82  ? 191 CYS A N   1 
ATOM   1554 C  CA  . CYS A 1 195 ? -2.805  -33.557 5.562   1   27.08  ? 191 CYS A CA  1 
ATOM   1555 C  C   . CYS A 1 195 ? -3.047  -33.959 7.008   1   27.46  ? 191 CYS A C   1 
ATOM   1556 O  O   . CYS A 1 195 ? -2.342  -34.829 7.504   1   26.97  ? 191 CYS A O   1 
ATOM   1557 C  CB  . CYS A 1 195 ? -2.022  -32.262 5.526   1   27.26  ? 191 CYS A CB  1 
ATOM   1558 S  SG  . CYS A 1 195 ? -1.481  -31.884 3.843   1   30.86  ? 191 CYS A SG  1 
ATOM   1559 N  N   . ILE A 1 196 ? -4.057  -33.342 7.659   1   27.94  ? 192 ILE A N   1 
ATOM   1560 C  CA  . ILE A 1 196 ? -4.34   -33.568 9.069   1   28.36  ? 192 ILE A CA  1 
ATOM   1561 C  C   . ILE A 1 196 ? -4.893  -34.986 9.26    1   32.19  ? 192 ILE A C   1 
ATOM   1562 O  O   . ILE A 1 196 ? -4.627  -35.624 10.294  1   31.84  ? 192 ILE A O   1 
ATOM   1563 C  CB  . ILE A 1 196 ? -5.308  -32.486 9.575   1   27.46  ? 192 ILE A CB  1 
ATOM   1564 C  CG1 . ILE A 1 196 ? -4.62   -31.158 9.646   1   25.59  ? 192 ILE A CG1 1 
ATOM   1565 C  CG2 . ILE A 1 196 ? -5.919  -32.862 10.933  1   26.77  ? 192 ILE A CG2 1 
ATOM   1566 C  CD1 . ILE A 1 196 ? -5.576  -29.986 9.633   1   28.45  ? 192 ILE A CD1 1 
ATOM   1567 N  N   . PHE A 1 197 ? -5.684  -35.454 8.263   1   31.18  ? 193 PHE A N   1 
ATOM   1568 C  CA  . PHE A 1 197 ? -6.286  -36.782 8.295   1   29.13  ? 193 PHE A CA  1 
ATOM   1569 C  C   . PHE A 1 197 ? -5.166  -37.809 8.364   1   30.2   ? 193 PHE A C   1 
ATOM   1570 O  O   . PHE A 1 197 ? -5.153  -38.641 9.272   1   36.69  ? 193 PHE A O   1 
ATOM   1571 C  CB  . PHE A 1 197 ? -7.158  -37.027 7.063   1   26.88  ? 193 PHE A CB  1 
ATOM   1572 C  CG  . PHE A 1 197 ? -7.802  -38.406 6.94    1   28.07  ? 193 PHE A CG  1 
ATOM   1573 C  CD1 . PHE A 1 197 ? -7.842  -39.299 8.016   1   28.04  ? 193 PHE A CD1 1 
ATOM   1574 C  CD2 . PHE A 1 197 ? -8.393  -38.809 5.742   1   27.13  ? 193 PHE A CD2 1 
ATOM   1575 C  CE1 . PHE A 1 197 ? -8.437  -40.55  7.881   1   27.81  ? 193 PHE A CE1 1 
ATOM   1576 C  CE2 . PHE A 1 197 ? -9.011  -40.052 5.616   1   27.52  ? 193 PHE A CE2 1 
ATOM   1577 C  CZ  . PHE A 1 197 ? -9.029  -40.926 6.683   1   27.78  ? 193 PHE A CZ  1 
ATOM   1578 N  N   . ALA A 1 198 ? -4.228  -37.715 7.413   1   28.3   ? 194 ALA A N   1 
ATOM   1579 C  CA  . ALA A 1 198 ? -3.061  -38.584 7.367   1   31.66  ? 194 ALA A CA  1 
ATOM   1580 C  C   . ALA A 1 198 ? -2.3    -38.497 8.697   1   34.25  ? 194 ALA A C   1 
ATOM   1581 O  O   . ALA A 1 198 ? -1.918  -39.522 9.265   1   35.34  ? 194 ALA A O   1 
ATOM   1582 C  CB  . ALA A 1 198 ? -2.182  -38.229 6.169   1   30.08  ? 194 ALA A CB  1 
ATOM   1583 N  N   . GLU A 1 199 ? -2.172  -37.272 9.232   1   33.61  ? 195 GLU A N   1 
ATOM   1584 C  CA  . GLU A 1 199 ? -1.419  -37.005 10.448  1   35.52  ? 195 GLU A CA  1 
ATOM   1585 C  C   . GLU A 1 199 ? -2.055  -37.687 11.665  1   37.32  ? 195 GLU A C   1 
ATOM   1586 O  O   . GLU A 1 199 ? -1.331  -38.198 12.518  1   40.22  ? 195 GLU A O   1 
ATOM   1587 C  CB  . GLU A 1 199 ? -1.139  -35.51  10.658  1   32.74  ? 195 GLU A CB  1 
ATOM   1588 C  CG  . GLU A 1 199 ? -0.074  -35.263 11.729  1   33.02  ? 195 GLU A CG  1 
ATOM   1589 C  CD  . GLU A 1 199 ? 0.372   -33.819 11.903  1   30.2   ? 195 GLU A CD  1 
ATOM   1590 O  OE1 . GLU A 1 199 ? -0.022  -33.049 11.012  1   28.81  ? 195 GLU A OE1 1 
ATOM   1591 O  OE2 . GLU A 1 199 ? 1.062   -33.461 12.899  1   30.96  ? 195 GLU A OE2 1 
ATOM   1592 N  N   . MET A 1 200 ? -3.393  -37.679 11.778  1   37.85  ? 196 MET A N   1 
ATOM   1593 C  CA  . MET A 1 200 ? -4.043  -38.409 12.867  1   36.91  ? 196 MET A CA  1 
ATOM   1594 C  C   . MET A 1 200 ? -3.712  -39.901 12.785  1   38.35  ? 196 MET A C   1 
ATOM   1595 O  O   . MET A 1 200 ? -3.531  -40.558 13.805  1   40.1   ? 196 MET A O   1 
ATOM   1596 C  CB  . MET A 1 200 ? -5.559  -38.185 12.911  1   31.51  ? 196 MET A CB  1 
ATOM   1597 C  CG  . MET A 1 200 ? -5.947  -36.834 13.414  1   28.66  ? 196 MET A CG  1 
ATOM   1598 S  SD  . MET A 1 200 ? -7.73   -36.657 13.586  1   30.66  ? 196 MET A SD  1 
ATOM   1599 C  CE  . MET A 1 200 ? -8.398  -36.688 11.919  1   28.45  ? 196 MET A CE  1 
ATOM   1600 N  N   . VAL A 1 201 ? -3.581  -40.425 11.561  1   38.62  ? 197 VAL A N   1 
ATOM   1601 C  CA  . VAL A 1 201 ? -3.354  -41.858 11.404  1   40.45  ? 197 VAL A CA  1 
ATOM   1602 C  C   . VAL A 1 201 ? -1.941  -42.249 11.851  1   42.92  ? 197 VAL A C   1 
ATOM   1603 O  O   . VAL A 1 201 ? -1.787  -43.245 12.554  1   44.87  ? 197 VAL A O   1 
ATOM   1604 C  CB  . VAL A 1 201 ? -3.647  -42.303 9.96    1   37.29  ? 197 VAL A CB  1 
ATOM   1605 C  CG1 . VAL A 1 201 ? -3.234  -43.75  9.745   1   37.6   ? 197 VAL A CG1 1 
ATOM   1606 C  CG2 . VAL A 1 201 ? -5.098  -42.047 9.573   1   34.52  ? 197 VAL A CG2 1 
ATOM   1607 N  N   . THR A 1 202 ? -0.946  -41.435 11.487  1   42.84  ? 198 THR A N   1 
ATOM   1608 C  CA  . THR A 1 202 ? 0.476   -41.741 11.733  1   44.32  ? 198 THR A CA  1 
ATOM   1609 C  C   . THR A 1 202 ? 1.029   -40.97  12.903  1   44.76  ? 198 THR A C   1 
ATOM   1610 O  O   . THR A 1 202 ? 2.093   -41.375 13.394  1   50.09  ? 198 THR A O   1 
ATOM   1611 C  CB  . THR A 1 202 ? 1.218   -41.351 10.458  1   44.64  ? 198 THR A CB  1 
ATOM   1612 O  OG1 . THR A 1 202 ? 1.148   -39.931 10.414  1   39.05  ? 198 THR A OG1 1 
ATOM   1613 C  CG2 . THR A 1 202 ? 0.586   -41.935 9.209   1   42.5   ? 198 THR A CG2 1 
ATOM   1614 N  N   . ARG A 1 203 ? 0.457   -39.93  13.353  1   43.52  ? 199 ARG A N   1 
ATOM   1615 C  CA  . ARG A 1 203 ? 0.982   -39.073 14.455  1   48.46  ? 199 ARG A CA  1 
ATOM   1616 C  C   . ARG A 1 203 ? 2.207   -38.288 13.949  1   46.85  ? 199 ARG A C   1 
ATOM   1617 O  O   . ARG A 1 203 ? 2.94    -37.753 14.787  1   51.55  ? 199 ARG A O   1 
ATOM   1618 C  CB  . ARG A 1 203 ? 1.16    -39.863 15.755  1   51.45  ? 199 ARG A CB  1 
ATOM   1619 C  CG  . ARG A 1 203 ? -0.133  -39.878 16.557  1   54.88  ? 199 ARG A CG  1 
ATOM   1620 C  CD  . ARG A 1 203 ? -0.303  -41.176 17.309  1   53.72  ? 199 ARG A CD  1 
ATOM   1621 N  NE  . ARG A 1 203 ? -0.134  -42.307 16.394  1   69.27  ? 199 ARG A NE  1 
ATOM   1622 C  CZ  . ARG A 1 203 ? 0.873   -43.162 16.437  1   74.22  ? 199 ARG A CZ  1 
ATOM   1623 N  NH1 . ARG A 1 203 ? 0.893   -44.198 15.621  1   71.26  ? 199 ARG A NH1 1 
ATOM   1624 N  NH2 . ARG A 1 203 ? 1.861   -42.972 17.291  1   78.11  ? 199 ARG A NH2 1 
ATOM   1625 N  N   . ARG A 1 204 ? 2.425   -38.1   12.735  1   45.56  ? 200 ARG A N   1 
ATOM   1626 C  CA  . ARG A 1 204 ? 3.539   -37.31  12.154  1   45.94  ? 200 ARG A CA  1 
ATOM   1627 C  C   . ARG A 1 204 ? 3.052   -36.564 10.896  1   45.71  ? 200 ARG A C   1 
ATOM   1628 O  O   . ARG A 1 204 ? 2.244   -37.144 10.159  1   46.17  ? 200 ARG A O   1 
ATOM   1629 C  CB  . ARG A 1 204 ? 4.668   -38.234 11.703  1   48.24  ? 200 ARG A CB  1 
ATOM   1630 C  CG  . ARG A 1 204 ? 4.255   -39.666 11.413  1   64.73  ? 200 ARG A CG  1 
ATOM   1631 C  CD  . ARG A 1 204 ? 5.355   -40.447 10.723  1   73.85  ? 200 ARG A CD  1 
ATOM   1632 N  NE  . ARG A 1 204 ? 5.461   -40.13  9.296   1   79.24  ? 200 ARG A NE  1 
ATOM   1633 C  CZ  . ARG A 1 204 ? 6.263   -40.771 8.459   1   79.69  ? 200 ARG A CZ  1 
ATOM   1634 N  NH1 . ARG A 1 204 ? 5.754   -41.49  7.477   1   85.1   ? 200 ARG A NH1 1 
ATOM   1635 N  NH2 . ARG A 1 204 ? 7.571   -40.699 8.612   1   80.29  ? 200 ARG A NH2 1 
ATOM   1636 N  N   . ALA A 1 205 ? 3.515   -35.436 10.592  1   40.73  ? 201 ALA A N   1 
ATOM   1637 C  CA  . ALA A 1 205 ? 3.159   -34.604 9.425   1   37.03  ? 201 ALA A CA  1 
ATOM   1638 C  C   . ALA A 1 205 ? 3.459   -35.317 8.112   1   35.56  ? 201 ALA A C   1 
ATOM   1639 O  O   . ALA A 1 205 ? 4.527   -35.896 7.969   1   35.59  ? 201 ALA A O   1 
ATOM   1640 C  CB  . ALA A 1 205 ? 3.789   -33.245 9.495   1   36.82  ? 201 ALA A CB  1 
ATOM   1641 N  N   . LEU A 1 206 ? 2.509   -35.227 7.194   1   32.45  ? 202 LEU A N   1 
ATOM   1642 C  CA  . LEU A 1 206 ? 2.573   -35.948 5.94    1   32.44  ? 202 LEU A CA  1 
ATOM   1643 C  C   . LEU A 1 206 ? 3.604   -35.272 5.039   1   32.86  ? 202 LEU A C   1 
ATOM   1644 O  O   . LEU A 1 206 ? 4.402   -35.932 4.406   1   36.97  ? 202 LEU A O   1 
ATOM   1645 C  CB  . LEU A 1 206 ? 1.165   -35.956 5.339   1   32.25  ? 202 LEU A CB  1 
ATOM   1646 C  CG  . LEU A 1 206 ? 0.997   -36.547 3.929   1   32.38  ? 202 LEU A CG  1 
ATOM   1647 C  CD1 . LEU A 1 206 ? 1.327   -38.062 3.926   1   32.57  ? 202 LEU A CD1 1 
ATOM   1648 C  CD2 . LEU A 1 206 ? -0.387  -36.22  3.343   1   26.07  ? 202 LEU A CD2 1 
ATOM   1649 N  N   . PHE A 1 207 ? 3.614   -33.949 4.972   1   29.7   ? 203 PHE A N   1 
ATOM   1650 C  CA  . PHE A 1 207 ? 4.628   -33.35  4.136   1   29.99  ? 203 PHE A CA  1 
ATOM   1651 C  C   . PHE A 1 207 ? 5.422   -32.339 4.949   1   33.01  ? 203 PHE A C   1 
ATOM   1652 O  O   . PHE A 1 207 ? 5.136   -31.15  4.871   1   39.86  ? 203 PHE A O   1 
ATOM   1653 C  CB  . PHE A 1 207 ? 3.906   -32.595 3.018   1   29.12  ? 203 PHE A CB  1 
ATOM   1654 C  CG  . PHE A 1 207 ? 3.041   -33.454 2.112   1   26.46  ? 203 PHE A CG  1 
ATOM   1655 C  CD1 . PHE A 1 207 ? 3.572   -34.589 1.507   1   26.7   ? 203 PHE A CD1 1 
ATOM   1656 C  CD2 . PHE A 1 207 ? 1.69    -33.149 1.923   1   24.17  ? 203 PHE A CD2 1 
ATOM   1657 C  CE1 . PHE A 1 207 ? 2.777   -35.395 0.686   1   28.61  ? 203 PHE A CE1 1 
ATOM   1658 C  CE2 . PHE A 1 207 ? 0.892   -33.954 1.105   1   24.34  ? 203 PHE A CE2 1 
ATOM   1659 C  CZ  . PHE A 1 207 ? 1.434   -35.069 0.47    1   25.61  ? 203 PHE A CZ  1 
ATOM   1660 N  N   . PRO A 1 208 ? 6.386   -32.741 5.804   1   33.88  ? 204 PRO A N   1 
ATOM   1661 C  CA  . PRO A 1 208 ? 7.105   -31.76  6.63    1   34.13  ? 204 PRO A CA  1 
ATOM   1662 C  C   . PRO A 1 208 ? 8.23    -31.047 5.882   1   34.91  ? 204 PRO A C   1 
ATOM   1663 O  O   . PRO A 1 208 ? 9.398   -31.337 6.105   1   37.05  ? 204 PRO A O   1 
ATOM   1664 C  CB  . PRO A 1 208 ? 7.651   -32.693 7.755   1   34.61  ? 204 PRO A CB  1 
ATOM   1665 C  CG  . PRO A 1 208 ? 7.975   -33.982 7.031   1   32.54  ? 204 PRO A CG  1 
ATOM   1666 C  CD  . PRO A 1 208 ? 6.767   -34.142 6.091   1   33.08  ? 204 PRO A CD  1 
ATOM   1667 N  N   . GLY A 1 209 ? 7.879   -30.127 4.987   1   33.8   ? 205 GLY A N   1 
ATOM   1668 C  CA  . GLY A 1 209 ? 8.882   -29.455 4.181   1   37.4   ? 205 GLY A CA  1 
ATOM   1669 C  C   . GLY A 1 209 ? 9.673   -28.41  4.983   1   41.33  ? 205 GLY A C   1 
ATOM   1670 O  O   . GLY A 1 209 ? 9.217   -27.946 6.026   1   41.31  ? 205 GLY A O   1 
ATOM   1671 N  N   . ASP A 1 210 ? 10.866  -28.047 4.48    1   43.8   ? 206 ASP A N   1 
ATOM   1672 C  CA  . ASP A 1 210 ? 11.803  -27.161 5.157   1   48.36  ? 206 ASP A CA  1 
ATOM   1673 C  C   . ASP A 1 210 ? 11.81   -25.807 4.453   1   46.41  ? 206 ASP A C   1 
ATOM   1674 O  O   . ASP A 1 210 ? 12.497  -24.894 4.893   1   48.71  ? 206 ASP A O   1 
ATOM   1675 C  CB  . ASP A 1 210 ? 13.224  -27.714 5.15    1   57.82  ? 206 ASP A CB  1 
ATOM   1676 C  CG  . ASP A 1 210 ? 13.45   -29.086 5.79    1   68.32  ? 206 ASP A CG  1 
ATOM   1677 O  OD1 . ASP A 1 210 ? 13.528  -29.168 7.04    1   74.99  ? 206 ASP A OD1 1 
ATOM   1678 O  OD2 . ASP A 1 210 ? 13.538  -30.087 5.038   1   62.48  ? 206 ASP A OD2 1 
ATOM   1679 N  N   . SER A 1 211 ? 11.08   -25.71  3.331   1   41.93  ? 207 SER A N   1 
ATOM   1680 C  CA  . SER A 1 211 ? 10.996  -24.535 2.475   1   38.67  ? 207 SER A CA  1 
ATOM   1681 C  C   . SER A 1 211 ? 9.882   -24.753 1.467   1   37.71  ? 207 SER A C   1 
ATOM   1682 O  O   . SER A 1 211 ? 9.354   -25.85  1.37    1   35.27  ? 207 SER A O   1 
ATOM   1683 C  CB  . SER A 1 211 ? 12.277  -24.269 1.76    1   41.03  ? 207 SER A CB  1 
ATOM   1684 O  OG  . SER A 1 211 ? 12.651  -25.353 0.922   1   42.92  ? 207 SER A OG  1 
ATOM   1685 N  N   . GLU A 1 212 ? 9.526   -23.707 0.717   1   39.3   ? 208 GLU A N   1 
ATOM   1686 C  CA  . GLU A 1 212 ? 8.451   -23.844 -0.248  1   37.06  ? 208 GLU A CA  1 
ATOM   1687 C  C   . GLU A 1 212 ? 8.818   -24.88  -1.315  1   36.78  ? 208 GLU A C   1 
ATOM   1688 O  O   . GLU A 1 212 ? 8.031   -25.775 -1.559  1   34.66  ? 208 GLU A O   1 
ATOM   1689 C  CB  . GLU A 1 212 ? 8.116   -22.493 -0.868  1   38.84  ? 208 GLU A CB  1 
ATOM   1690 C  CG  . GLU A 1 212 ? 7.565   -21.478 0.123   1   40.24  ? 208 GLU A CG  1 
ATOM   1691 C  CD  . GLU A 1 212 ? 7.297   -20.191 -0.637  1   45.5   ? 208 GLU A CD  1 
ATOM   1692 O  OE1 . GLU A 1 212 ? 6.313   -20.191 -1.403  1   46.01  ? 208 GLU A OE1 1 
ATOM   1693 O  OE2 . GLU A 1 212 ? 8.096   -19.217 -0.52   1   49.29  ? 208 GLU A OE2 1 
ATOM   1694 N  N   . ILE A 1 213 ? 10.026  -24.815 -1.906  1   40.05  ? 209 ILE A N   1 
ATOM   1695 C  CA  . ILE A 1 213 ? 10.417  -25.802 -2.91   1   40.76  ? 209 ILE A CA  1 
ATOM   1696 C  C   . ILE A 1 213 ? 10.493  -27.218 -2.314  1   40.35  ? 209 ILE A C   1 
ATOM   1697 O  O   . ILE A 1 213 ? 10.022  -28.181 -2.945  1   40.01  ? 209 ILE A O   1 
ATOM   1698 C  CB  . ILE A 1 213 ? 11.678  -25.402 -3.701  1   42.86  ? 209 ILE A CB  1 
ATOM   1699 C  CG1 . ILE A 1 213 ? 11.788  -26.226 -4.961  1   42.98  ? 209 ILE A CG1 1 
ATOM   1700 C  CG2 . ILE A 1 213 ? 12.959  -25.482 -2.881  1   49.21  ? 209 ILE A CG2 1 
ATOM   1701 C  CD1 . ILE A 1 213 ? 10.749  -25.803 -5.989  1   43.73  ? 209 ILE A CD1 1 
ATOM   1702 N  N   . ASP A 1 214 ? 11.02   -27.33  -1.078  1   36.77  ? 210 ASP A N   1 
ATOM   1703 C  CA  . ASP A 1 214 ? 11.125  -28.619 -0.416  1   36.39  ? 210 ASP A CA  1 
ATOM   1704 C  C   . ASP A 1 214 ? 9.74    -29.214 -0.173  1   35.17  ? 210 ASP A C   1 
ATOM   1705 O  O   . ASP A 1 214 ? 9.55    -30.421 -0.299  1   35.79  ? 210 ASP A O   1 
ATOM   1706 C  CB  . ASP A 1 214 ? 12.021  -28.594 0.812   1   39.37  ? 210 ASP A CB  1 
ATOM   1707 C  CG  . ASP A 1 214 ? 12.16   -29.955 1.499   1   42.01  ? 210 ASP A CG  1 
ATOM   1708 O  OD1 . ASP A 1 214 ? 12.765  -30.897 0.871   1   41.92  ? 210 ASP A OD1 1 
ATOM   1709 O  OD2 . ASP A 1 214 ? 11.643  -30.07  2.642   1   37.56  ? 210 ASP A OD2 1 
ATOM   1710 N  N   . GLN A 1 215 ? 8.784   -28.355 0.197   1   33.9   ? 211 GLN A N   1 
ATOM   1711 C  CA  . GLN A 1 215 ? 7.413   -28.76  0.461   1   33.13  ? 211 GLN A CA  1 
ATOM   1712 C  C   . GLN A 1 215 ? 6.819   -29.336 -0.82   1   32.97  ? 211 GLN A C   1 
ATOM   1713 O  O   . GLN A 1 215 ? 6.217   -30.406 -0.82   1   32.84  ? 211 GLN A O   1 
ATOM   1714 C  CB  . GLN A 1 215 ? 6.583   -27.55  0.892   1   31.11  ? 211 GLN A CB  1 
ATOM   1715 C  CG  . GLN A 1 215 ? 5.17    -27.861 1.365   1   29.98  ? 211 GLN A CG  1 
ATOM   1716 C  CD  . GLN A 1 215 ? 5.16    -28.657 2.656   1   32.98  ? 211 GLN A CD  1 
ATOM   1717 O  OE1 . GLN A 1 215 ? 6.074   -28.531 3.487   1   33.22  ? 211 GLN A OE1 1 
ATOM   1718 N  NE2 . GLN A 1 215 ? 4.139   -29.504 2.811   1   30.91  ? 211 GLN A NE2 1 
ATOM   1719 N  N   . LEU A 1 216 ? 7.043   -28.627 -1.921  1   32.69  ? 212 LEU A N   1 
ATOM   1720 C  CA  . LEU A 1 216 ? 6.464   -29.013 -3.189  1   33.09  ? 212 LEU A CA  1 
ATOM   1721 C  C   . LEU A 1 216 ? 7.082   -30.328 -3.665  1   34.77  ? 212 LEU A C   1 
ATOM   1722 O  O   . LEU A 1 216 ? 6.378   -31.194 -4.191  1   33.52  ? 212 LEU A O   1 
ATOM   1723 C  CB  . LEU A 1 216 ? 6.804   -27.849 -4.112  1   35.37  ? 212 LEU A CB  1 
ATOM   1724 C  CG  . LEU A 1 216 ? 6.069   -27.84  -5.443  1   39.49  ? 212 LEU A CG  1 
ATOM   1725 C  CD1 . LEU A 1 216 ? 4.579   -27.621 -5.137  1   35.57  ? 212 LEU A CD1 1 
ATOM   1726 C  CD2 . LEU A 1 216 ? 6.67    -26.746 -6.322  1   41.56  ? 212 LEU A CD2 1 
ATOM   1727 N  N   . PHE A 1 217 ? 8.363   -30.526 -3.385  1   33.84  ? 213 PHE A N   1 
ATOM   1728 C  CA  . PHE A 1 217 ? 9.062   -31.744 -3.862  1   32.89  ? 213 PHE A CA  1 
ATOM   1729 C  C   . PHE A 1 217 ? 8.674   -32.942 -2.996  1   35.04  ? 213 PHE A C   1 
ATOM   1730 O  O   . PHE A 1 217 ? 8.703   -34.061 -3.505  1   37.42  ? 213 PHE A O   1 
ATOM   1731 C  CB  . PHE A 1 217 ? 10.559  -31.436 -3.92   1   31.7   ? 213 PHE A CB  1 
ATOM   1732 C  CG  . PHE A 1 217 ? 11.025  -30.639 -5.128  1   31.12  ? 213 PHE A CG  1 
ATOM   1733 C  CD1 . PHE A 1 217 ? 10.126  -30.213 -6.095  1   29.93  ? 213 PHE A CD1 1 
ATOM   1734 C  CD2 . PHE A 1 217 ? 12.366  -30.317 -5.291  1   31.29  ? 213 PHE A CD2 1 
ATOM   1735 C  CE1 . PHE A 1 217 ? 10.559  -29.489 -7.19   1   29.52  ? 213 PHE A CE1 1 
ATOM   1736 C  CE2 . PHE A 1 217 ? 12.791  -29.593 -6.389  1   31.46  ? 213 PHE A CE2 1 
ATOM   1737 C  CZ  . PHE A 1 217 ? 11.887  -29.18  -7.334  1   30.59  ? 213 PHE A CZ  1 
ATOM   1738 N  N   . ARG A 1 218 ? 8.299   -32.711 -1.742  1   32.69  ? 214 ARG A N   1 
ATOM   1739 C  CA  . ARG A 1 218 ? 7.844   -33.815 -0.86   1   34.7   ? 214 ARG A CA  1 
ATOM   1740 C  C   . ARG A 1 218 ? 6.459   -34.244 -1.334  1   31.05  ? 214 ARG A C   1 
ATOM   1741 O  O   . ARG A 1 218 ? 6.229   -35.45  -1.44   1   32.39  ? 214 ARG A O   1 
ATOM   1742 C  CB  . ARG A 1 218 ? 7.873   -33.364 0.599   1   39.45  ? 214 ARG A CB  1 
ATOM   1743 C  CG  . ARG A 1 218 ? 9.223   -33.418 1.29    1   41.1   ? 214 ARG A CG  1 
ATOM   1744 C  CD  . ARG A 1 218 ? 9.082   -32.819 2.67    1   44.03  ? 214 ARG A CD  1 
ATOM   1745 N  NE  . ARG A 1 218 ? 10.386  -32.494 3.25    1   40.22  ? 214 ARG A NE  1 
ATOM   1746 C  CZ  . ARG A 1 218 ? 10.982  -33.224 4.171   1   40.09  ? 214 ARG A CZ  1 
ATOM   1747 N  NH1 . ARG A 1 218 ? 10.47   -34.388 4.515   1   37.63  ? 214 ARG A NH1 1 
ATOM   1748 N  NH2 . ARG A 1 218 ? 12.079  -32.784 4.751   1   42.45  ? 214 ARG A NH2 1 
ATOM   1749 N  N   . ILE A 1 219 ? 5.57    -33.286 -1.543  1   28.35  ? 215 ILE A N   1 
ATOM   1750 C  CA  . ILE A 1 219 ? 4.283   -33.575 -2.154  1   28.67  ? 215 ILE A CA  1 
ATOM   1751 C  C   . ILE A 1 219 ? 4.464   -34.365 -3.449  1   29.77  ? 215 ILE A C   1 
ATOM   1752 O  O   . ILE A 1 219 ? 3.902   -35.456 -3.582  1   30.85  ? 215 ILE A O   1 
ATOM   1753 C  CB  . ILE A 1 219 ? 3.466   -32.302 -2.413  1   27.55  ? 215 ILE A CB  1 
ATOM   1754 C  CG1 . ILE A 1 219 ? 3.171   -31.578 -1.081  1   28.01  ? 215 ILE A CG1 1 
ATOM   1755 C  CG2 . ILE A 1 219 ? 2.174   -32.685 -3.139  1   24.83  ? 215 ILE A CG2 1 
ATOM   1756 C  CD1 . ILE A 1 219 ? 2.574   -30.183 -1.247  1   27.73  ? 215 ILE A CD1 1 
ATOM   1757 N  N   . PHE A 1 220 ? 5.255   -33.822 -4.378  1   28.67  ? 216 PHE A N   1 
ATOM   1758 C  CA  . PHE A 1 220 ? 5.476   -34.494 -5.644  1   29.52  ? 216 PHE A CA  1 
ATOM   1759 C  C   . PHE A 1 220 ? 6.036   -35.901 -5.422  1   31.08  ? 216 PHE A C   1 
ATOM   1760 O  O   . PHE A 1 220 ? 5.663   -36.818 -6.155  1   32.07  ? 216 PHE A O   1 
ATOM   1761 C  CB  . PHE A 1 220 ? 6.466   -33.768 -6.558  1   29.71  ? 216 PHE A CB  1 
ATOM   1762 C  CG  . PHE A 1 220 ? 6.076   -32.416 -7.134  1   29.3   ? 216 PHE A CG  1 
ATOM   1763 C  CD1 . PHE A 1 220 ? 4.788   -31.895 -6.968  1   28.63  ? 216 PHE A CD1 1 
ATOM   1764 C  CD2 . PHE A 1 220 ? 6.999   -31.697 -7.901  1   30.61  ? 216 PHE A CD2 1 
ATOM   1765 C  CE1 . PHE A 1 220 ? 4.449   -30.652 -7.497  1   28.81  ? 216 PHE A CE1 1 
ATOM   1766 C  CE2 . PHE A 1 220 ? 6.641   -30.473 -8.474  1   31.53  ? 216 PHE A CE2 1 
ATOM   1767 C  CZ  . PHE A 1 220 ? 5.376   -29.947 -8.259  1   29.84  ? 216 PHE A CZ  1 
ATOM   1768 N  N   . ARG A 1 221 ? 6.958   -36.074 -4.462  1   30.13  ? 217 ARG A N   1 
ATOM   1769 C  CA  . ARG A 1 221 ? 7.577   -37.378 -4.252  1   32.17  ? 217 ARG A CA  1 
ATOM   1770 C  C   . ARG A 1 221 ? 6.583   -38.419 -3.724  1   33.53  ? 217 ARG A C   1 
ATOM   1771 O  O   . ARG A 1 221 ? 6.807   -39.609 -3.899  1   33.56  ? 217 ARG A O   1 
ATOM   1772 C  CB  . ARG A 1 221 ? 8.824   -37.331 -3.366  1   33.1   ? 217 ARG A CB  1 
ATOM   1773 C  CG  . ARG A 1 221 ? 10.006  -36.903 -4.232  1   34.37  ? 217 ARG A CG  1 
ATOM   1774 C  CD  . ARG A 1 221 ? 11.335  -37.183 -3.58   1   36.63  ? 217 ARG A CD  1 
ATOM   1775 N  NE  . ARG A 1 221 ? 11.41   -36.394 -2.345  1   38.44  ? 217 ARG A NE  1 
ATOM   1776 C  CZ  . ARG A 1 221 ? 11.965  -35.18  -2.239  1   40.31  ? 217 ARG A CZ  1 
ATOM   1777 N  NH1 . ARG A 1 221 ? 11.928  -34.542 -1.093  1   40.94  ? 217 ARG A NH1 1 
ATOM   1778 N  NH2 . ARG A 1 221 ? 12.523  -34.574 -3.269  1   39.58  ? 217 ARG A NH2 1 
ATOM   1779 N  N   . THR A 1 222 ? 5.474   -37.966 -3.13   1   33.13  ? 218 THR A N   1 
ATOM   1780 C  CA  . THR A 1 222 ? 4.435   -38.812 -2.578  1   35.03  ? 218 THR A CA  1 
ATOM   1781 C  C   . THR A 1 222 ? 3.303   -39.043 -3.595  1   37.49  ? 218 THR A C   1 
ATOM   1782 O  O   . THR A 1 222 ? 2.919   -40.183 -3.831  1   43.89  ? 218 THR A O   1 
ATOM   1783 C  CB  . THR A 1 222 ? 3.932   -38.103 -1.323  1   33.45  ? 218 THR A CB  1 
ATOM   1784 O  OG1 . THR A 1 222 ? 5.043   -38.132 -0.441  1   34.75  ? 218 THR A OG1 1 
ATOM   1785 C  CG2 . THR A 1 222 ? 2.768   -38.82  -0.678  1   33.56  ? 218 THR A CG2 1 
ATOM   1786 N  N   . LEU A 1 223 ? 2.775   -37.979 -4.221  1   34.43  ? 219 LEU A N   1 
ATOM   1787 C  CA  . LEU A 1 223 ? 1.581   -38.094 -5.05   1   33.19  ? 219 LEU A CA  1 
ATOM   1788 C  C   . LEU A 1 223 ? 1.953   -38.122 -6.521  1   34.06  ? 219 LEU A C   1 
ATOM   1789 O  O   . LEU A 1 223 ? 1.061   -38.204 -7.375  1   36.13  ? 219 LEU A O   1 
ATOM   1790 C  CB  . LEU A 1 223 ? 0.749   -36.854 -4.755  1   32.34  ? 219 LEU A CB  1 
ATOM   1791 C  CG  . LEU A 1 223 ? 0.292   -36.689 -3.298  1   31.78  ? 219 LEU A CG  1 
ATOM   1792 C  CD1 . LEU A 1 223 ? -0.701  -35.541 -3.231  1   28.96  ? 219 LEU A CD1 1 
ATOM   1793 C  CD2 . LEU A 1 223 ? -0.33   -38.021 -2.905  1   33     ? 219 LEU A CD2 1 
ATOM   1794 N  N   . GLY A 1 224 ? 3.261   -37.965 -6.798  1   31.83  ? 220 GLY A N   1 
ATOM   1795 C  CA  . GLY A 1 224 ? 3.786   -37.903 -8.157  1   31.88  ? 220 GLY A CA  1 
ATOM   1796 C  C   . GLY A 1 224 ? 3.849   -36.468 -8.661  1   30.92  ? 220 GLY A C   1 
ATOM   1797 O  O   . GLY A 1 224 ? 3.051   -35.635 -8.226  1   29.22  ? 220 GLY A O   1 
ATOM   1798 N  N   . THR A 1 225 ? 4.798   -36.168 -9.559  1   30.43  ? 221 THR A N   1 
ATOM   1799 C  CA  . THR A 1 225 ? 4.833   -34.807 -10.074 1   31.46  ? 221 THR A CA  1 
ATOM   1800 C  C   . THR A 1 225 ? 3.626   -34.623 -10.998 1   34.93  ? 221 THR A C   1 
ATOM   1801 O  O   . THR A 1 225 ? 3.444   -35.398 -11.933 1   36.58  ? 221 THR A O   1 
ATOM   1802 C  CB  . THR A 1 225 ? 6.124   -34.508 -10.825 1   32.82  ? 221 THR A CB  1 
ATOM   1803 O  OG1 . THR A 1 225 ? 7.222   -34.887 -10.003 1   34.77  ? 221 THR A OG1 1 
ATOM   1804 C  CG2 . THR A 1 225 ? 6.216   -33.062 -11.264 1   30.99  ? 221 THR A CG2 1 
ATOM   1805 N  N   . PRO A 1 226 ? 2.755   -33.611 -10.779 1   36.32  ? 222 PRO A N   1 
ATOM   1806 C  CA  . PRO A 1 226 ? 1.571   -33.433 -11.629 1   36.77  ? 222 PRO A CA  1 
ATOM   1807 C  C   . PRO A 1 226 ? 1.947   -33.058 -13.062 1   39.61  ? 222 PRO A C   1 
ATOM   1808 O  O   . PRO A 1 226 ? 2.934   -32.363 -13.296 1   42.02  ? 222 PRO A O   1 
ATOM   1809 C  CB  . PRO A 1 226 ? 0.812   -32.303 -10.915 1   34.99  ? 222 PRO A CB  1 
ATOM   1810 C  CG  . PRO A 1 226 ? 1.89    -31.542 -10.183 1   34.8   ? 222 PRO A CG  1 
ATOM   1811 C  CD  . PRO A 1 226 ? 2.894   -32.579 -9.734  1   34.93  ? 222 PRO A CD  1 
ATOM   1812 N  N   . ASP A 1 227 ? 1.166   -33.53  -14.038 1   41.02  ? 223 ASP A N   1 
ATOM   1813 C  CA  . ASP A 1 227 ? 1.353   -33.123 -15.427 1   43.04  ? 223 ASP A CA  1 
ATOM   1814 C  C   . ASP A 1 227 ? 0.004   -32.625 -15.957 1   43.46  ? 223 ASP A C   1 
ATOM   1815 O  O   . ASP A 1 227 ? -0.962  -32.532 -15.194 1   40.16  ? 223 ASP A O   1 
ATOM   1816 C  CB  . ASP A 1 227 ? 1.911   -34.269 -16.258 1   44.5   ? 223 ASP A CB  1 
ATOM   1817 C  CG  . ASP A 1 227 ? 0.961   -35.456 -16.355 1   48.03  ? 223 ASP A CG  1 
ATOM   1818 O  OD1 . ASP A 1 227 ? -0.174  -35.362 -15.832 1   46.81  ? 223 ASP A OD1 1 
ATOM   1819 O  OD2 . ASP A 1 227 ? 1.346   -36.461 -16.962 1   50.97  ? 223 ASP A OD2 1 
ATOM   1820 N  N   . GLU A 1 228 ? -0.085  -32.36  -17.273 1   44.77  ? 224 GLU A N   1 
ATOM   1821 C  CA  . GLU A 1 228 ? -1.278  -31.736 -17.832 1   42.31  ? 224 GLU A CA  1 
ATOM   1822 C  C   . GLU A 1 228 ? -2.472  -32.696 -17.734 1   44.78  ? 224 GLU A C   1 
ATOM   1823 O  O   . GLU A 1 228 ? -3.625  -32.27  -17.568 1   44.21  ? 224 GLU A O   1 
ATOM   1824 C  CB  . GLU A 1 228 ? -0.999  -31.17  -19.221 1   41.76  ? 224 GLU A CB  1 
ATOM   1825 C  CG  . GLU A 1 228 ? -0.225  -29.856 -19.224 1   41.93  ? 224 GLU A CG  1 
ATOM   1826 C  CD  . GLU A 1 228 ? -0.954  -28.588 -18.809 1   43.86  ? 224 GLU A CD  1 
ATOM   1827 O  OE1 . GLU A 1 228 ? -2.22   -28.598 -18.773 1   41.84  ? 224 GLU A OE1 1 
ATOM   1828 O  OE2 . GLU A 1 228 ? -0.242  -27.591 -18.478 1   42.17  ? 224 GLU A OE2 1 
ATOM   1829 N  N   . VAL A 1 229 ? -2.187  -34.005 -17.788 1   44.86  ? 225 VAL A N   1 
ATOM   1830 C  CA  . VAL A 1 229 ? -3.237  -35.002 -17.642 1   45.66  ? 225 VAL A CA  1 
ATOM   1831 C  C   . VAL A 1 229 ? -3.86   -34.919 -16.242 1   45.03  ? 225 VAL A C   1 
ATOM   1832 O  O   . VAL A 1 229 ? -5.064  -34.747 -16.092 1   41.93  ? 225 VAL A O   1 
ATOM   1833 C  CB  . VAL A 1 229 ? -2.692  -36.411 -17.934 1   46.74  ? 225 VAL A CB  1 
ATOM   1834 C  CG1 . VAL A 1 229 ? -3.836  -37.421 -18.004 1   46.16  ? 225 VAL A CG1 1 
ATOM   1835 C  CG2 . VAL A 1 229 ? -1.83   -36.43  -19.196 1   47.74  ? 225 VAL A CG2 1 
ATOM   1836 N  N   . VAL A 1 230 ? -3.035  -35.004 -15.198 1   42.69  ? 226 VAL A N   1 
ATOM   1837 C  CA  . VAL A 1 230 ? -3.576  -35.037 -13.854 1   42.67  ? 226 VAL A CA  1 
ATOM   1838 C  C   . VAL A 1 230 ? -4.211  -33.706 -13.473 1   38.98  ? 226 VAL A C   1 
ATOM   1839 O  O   . VAL A 1 230 ? -5.157  -33.706 -12.695 1   39.74  ? 226 VAL A O   1 
ATOM   1840 C  CB  . VAL A 1 230 ? -2.494  -35.438 -12.838 1   43.72  ? 226 VAL A CB  1 
ATOM   1841 C  CG1 . VAL A 1 230 ? -3.017  -35.291 -11.422 1   45.07  ? 226 VAL A CG1 1 
ATOM   1842 C  CG2 . VAL A 1 230 ? -2.036  -36.873 -13.061 1   45.36  ? 226 VAL A CG2 1 
ATOM   1843 N  N   . TRP A 1 231 ? -3.635  -32.586 -13.932 1   38.68  ? 227 TRP A N   1 
ATOM   1844 C  CA  . TRP A 1 231 ? -3.985  -31.259 -13.424 1   37.1   ? 227 TRP A CA  1 
ATOM   1845 C  C   . TRP A 1 231 ? -3.908  -30.255 -14.572 1   39.53  ? 227 TRP A C   1 
ATOM   1846 O  O   . TRP A 1 231 ? -2.89   -29.603 -14.753 1   42.16  ? 227 TRP A O   1 
ATOM   1847 C  CB  . TRP A 1 231 ? -3.006  -30.872 -12.304 1   32.55  ? 227 TRP A CB  1 
ATOM   1848 C  CG  . TRP A 1 231 ? -3.321  -29.589 -11.582 1   33.47  ? 227 TRP A CG  1 
ATOM   1849 C  CD1 . TRP A 1 231 ? -4.299  -28.691 -11.894 1   35.75  ? 227 TRP A CD1 1 
ATOM   1850 C  CD2 . TRP A 1 231 ? -2.598  -29.004 -10.473 1   34.8   ? 227 TRP A CD2 1 
ATOM   1851 N  NE1 . TRP A 1 231 ? -4.295  -27.636 -11.018 1   33.78  ? 227 TRP A NE1 1 
ATOM   1852 C  CE2 . TRP A 1 231 ? -3.245  -27.782 -10.152 1   33.64  ? 227 TRP A CE2 1 
ATOM   1853 C  CE3 . TRP A 1 231 ? -1.466  -29.38  -9.724  1   35.86  ? 227 TRP A CE3 1 
ATOM   1854 C  CZ2 . TRP A 1 231 ? -2.802  -26.943 -9.125  1   31.44  ? 227 TRP A CZ2 1 
ATOM   1855 C  CZ3 . TRP A 1 231 ? -1.008  -28.534 -8.727  1   33.53  ? 227 TRP A CZ3 1 
ATOM   1856 C  CH2 . TRP A 1 231 ? -1.665  -27.325 -8.441  1   32.65  ? 227 TRP A CH2 1 
ATOM   1857 N  N   . PRO A 1 232 ? -4.916  -30.132 -15.458 1   43.59  ? 228 PRO A N   1 
ATOM   1858 C  CA  . PRO A 1 232 ? -4.766  -29.263 -16.639 1   45.83  ? 228 PRO A CA  1 
ATOM   1859 C  C   . PRO A 1 232 ? -4.484  -27.822 -16.198 1   47.29  ? 228 PRO A C   1 
ATOM   1860 O  O   . PRO A 1 232 ? -5.129  -27.325 -15.253 1   43.48  ? 228 PRO A O   1 
ATOM   1861 C  CB  . PRO A 1 232 ? -6.075  -29.405 -17.445 1   42.59  ? 228 PRO A CB  1 
ATOM   1862 C  CG  . PRO A 1 232 ? -6.713  -30.646 -16.852 1   45.69  ? 228 PRO A CG  1 
ATOM   1863 C  CD  . PRO A 1 232 ? -6.224  -30.807 -15.395 1   45.33  ? 228 PRO A CD  1 
ATOM   1864 N  N   . GLY A 1 233 ? -3.465  -27.211 -16.841 1   45.78  ? 229 GLY A N   1 
ATOM   1865 C  CA  . GLY A 1 233 ? -2.994  -25.867 -16.528 1   49.02  ? 229 GLY A CA  1 
ATOM   1866 C  C   . GLY A 1 233 ? -1.707  -25.815 -15.689 1   53.8   ? 229 GLY A C   1 
ATOM   1867 O  O   . GLY A 1 233 ? -1.018  -24.79  -15.68  1   57.18  ? 229 GLY A O   1 
ATOM   1868 N  N   . VAL A 1 234 ? -1.372  -26.911 -14.987 1   49.26  ? 230 VAL A N   1 
ATOM   1869 C  CA  . VAL A 1 234 ? -0.307  -26.882 -13.998 1   44.4   ? 230 VAL A CA  1 
ATOM   1870 C  C   . VAL A 1 234 ? 0.975   -26.373 -14.669 1   46.86  ? 230 VAL A C   1 
ATOM   1871 O  O   . VAL A 1 234 ? 1.668   -25.531 -14.083 1   48.88  ? 230 VAL A O   1 
ATOM   1872 C  CB  . VAL A 1 234 ? -0.107  -28.193 -13.204 1   39.16  ? 230 VAL A CB  1 
ATOM   1873 C  CG1 . VAL A 1 234 ? 0.414   -29.318 -14.104 1   40.66  ? 230 VAL A CG1 1 
ATOM   1874 C  CG2 . VAL A 1 234 ? 0.812   -28.018 -11.998 1   34.79  ? 230 VAL A CG2 1 
ATOM   1875 N  N   . THR A 1 235 ? 1.278   -26.842 -15.895 1   44.54  ? 231 THR A N   1 
ATOM   1876 C  CA  . THR A 1 235 ? 2.562   -26.488 -16.498 1   46.16  ? 231 THR A CA  1 
ATOM   1877 C  C   . THR A 1 235 ? 2.604   -24.997 -16.853 1   46.56  ? 231 THR A C   1 
ATOM   1878 O  O   . THR A 1 235 ? 3.647   -24.495 -17.264 1   46.94  ? 231 THR A O   1 
ATOM   1879 C  CB  . THR A 1 235 ? 3.047   -27.374 -17.661 1   49.42  ? 231 THR A CB  1 
ATOM   1880 O  OG1 . THR A 1 235 ? 2.216   -27.168 -18.797 1   55.3   ? 231 THR A OG1 1 
ATOM   1881 C  CG2 . THR A 1 235 ? 3.189   -28.857 -17.344 1   47.39  ? 231 THR A CG2 1 
ATOM   1882 N  N   . SER A 1 236 ? 1.497   -24.275 -16.669 1   46.03  ? 232 SER A N   1 
ATOM   1883 C  CA  . SER A 1 236 ? 1.493   -22.85  -16.985 1   55.26  ? 232 SER A CA  1 
ATOM   1884 C  C   . SER A 1 236 ? 1.345   -21.988 -15.734 1   55.63  ? 232 SER A C   1 
ATOM   1885 O  O   . SER A 1 236 ? 1.159   -20.784 -15.837 1   59.19  ? 232 SER A O   1 
ATOM   1886 C  CB  . SER A 1 236 ? 0.394   -22.502 -17.969 1   62.23  ? 232 SER A CB  1 
ATOM   1887 O  OG  . SER A 1 236 ? 0.753   -22.937 -19.268 1   81.77  ? 232 SER A OG  1 
ATOM   1888 N  N   . MET A 1 237 ? 1.396   -22.593 -14.551 1   51.26  ? 233 MET A N   1 
ATOM   1889 C  CA  . MET A 1 237 ? 1.214   -21.815 -13.339 1   44.63  ? 233 MET A CA  1 
ATOM   1890 C  C   . MET A 1 237 ? 2.46    -20.978 -13.059 1   41.64  ? 233 MET A C   1 
ATOM   1891 O  O   . MET A 1 237 ? 3.568   -21.343 -13.432 1   42.37  ? 233 MET A O   1 
ATOM   1892 C  CB  . MET A 1 237 ? 0.895   -22.764 -12.193 1   46.41  ? 233 MET A CB  1 
ATOM   1893 C  CG  . MET A 1 237 ? -0.208  -23.661 -12.627 1   51.05  ? 233 MET A CG  1 
ATOM   1894 S  SD  . MET A 1 237 ? -1.09   -24.406 -11.256 1   57.89  ? 233 MET A SD  1 
ATOM   1895 C  CE  . MET A 1 237 ? -2.665  -24.722 -12.068 1   59.37  ? 233 MET A CE  1 
ATOM   1896 N  N   . PRO A 1 238 ? 2.33    -19.808 -12.403 1   40.01  ? 234 PRO A N   1 
ATOM   1897 C  CA  . PRO A 1 238 ? 3.418   -18.844 -12.372 1   39.73  ? 234 PRO A CA  1 
ATOM   1898 C  C   . PRO A 1 238 ? 4.709   -19.456 -11.842 1   38.56  ? 234 PRO A C   1 
ATOM   1899 O  O   . PRO A 1 238 ? 5.779   -19.082 -12.302 1   40.5   ? 234 PRO A O   1 
ATOM   1900 C  CB  . PRO A 1 238 ? 2.833   -17.719 -11.474 1   40.83  ? 234 PRO A CB  1 
ATOM   1901 C  CG  . PRO A 1 238 ? 1.33    -17.82  -11.677 1   38.28  ? 234 PRO A CG  1 
ATOM   1902 C  CD  . PRO A 1 238 ? 1.145   -19.329 -11.671 1   39.57  ? 234 PRO A CD  1 
ATOM   1903 N  N   . ASP A 1 239 ? 4.614   -20.385 -10.881 1   38.07  ? 235 ASP A N   1 
ATOM   1904 C  CA  . ASP A 1 239 ? 5.82    -20.877 -10.222 1   39.21  ? 235 ASP A CA  1 
ATOM   1905 C  C   . ASP A 1 239 ? 6.113   -22.312 -10.622 1   39.79  ? 235 ASP A C   1 
ATOM   1906 O  O   . ASP A 1 239 ? 6.945   -22.956 -10.003 1   39.46  ? 235 ASP A O   1 
ATOM   1907 C  CB  . ASP A 1 239 ? 5.845   -20.59  -8.726  1   36.61  ? 235 ASP A CB  1 
ATOM   1908 C  CG  . ASP A 1 239 ? 6.048   -19.122 -8.433  1   36.45  ? 235 ASP A CG  1 
ATOM   1909 O  OD1 . ASP A 1 239 ? 6.814   -18.486 -9.155  1   39.09  ? 235 ASP A OD1 1 
ATOM   1910 O  OD2 . ASP A 1 239 ? 5.424   -18.63  -7.518  1   38.74  ? 235 ASP A OD2 1 
ATOM   1911 N  N   . TYR A 1 240 ? 5.408   -22.798 -11.644 1   42.11  ? 236 TYR A N   1 
ATOM   1912 C  CA  . TYR A 1 240 ? 5.773   -24.062 -12.259 1   45.67  ? 236 TYR A CA  1 
ATOM   1913 C  C   . TYR A 1 240 ? 7.124   -23.858 -12.94  1   45.71  ? 236 TYR A C   1 
ATOM   1914 O  O   . TYR A 1 240 ? 7.381   -22.784 -13.48  1   48.39  ? 236 TYR A O   1 
ATOM   1915 C  CB  . TYR A 1 240 ? 4.689   -24.559 -13.228 1   49.02  ? 236 TYR A CB  1 
ATOM   1916 C  CG  . TYR A 1 240 ? 5.071   -25.922 -13.773 1   50.67  ? 236 TYR A CG  1 
ATOM   1917 C  CD1 . TYR A 1 240 ? 4.917   -27.05  -12.978 1   52.46  ? 236 TYR A CD1 1 
ATOM   1918 C  CD2 . TYR A 1 240 ? 5.648   -26.074 -15.032 1   55.28  ? 236 TYR A CD2 1 
ATOM   1919 C  CE1 . TYR A 1 240 ? 5.303   -28.304 -13.424 1   60.6   ? 236 TYR A CE1 1 
ATOM   1920 C  CE2 . TYR A 1 240 ? 6.032   -27.327 -15.498 1   61.42  ? 236 TYR A CE2 1 
ATOM   1921 C  CZ  . TYR A 1 240 ? 5.854   -28.441 -14.689 1   64.72  ? 236 TYR A CZ  1 
ATOM   1922 O  OH  . TYR A 1 240 ? 6.226   -29.687 -15.1   1   73.55  ? 236 TYR A OH  1 
ATOM   1923 N  N   . LYS A 1 241 ? 7.983   -24.883 -12.903 1   44.17  ? 237 LYS A N   1 
ATOM   1924 C  CA  . LYS A 1 241 ? 9.23    -24.868 -13.646 1   43.76  ? 237 LYS A CA  1 
ATOM   1925 C  C   . LYS A 1 241 ? 9.337   -26.169 -14.442 1   42.39  ? 237 LYS A C   1 
ATOM   1926 O  O   . LYS A 1 241 ? 9.272   -27.245 -13.858 1   42.95  ? 237 LYS A O   1 
ATOM   1927 C  CB  . LYS A 1 241 ? 10.404  -24.641 -12.686 1   44.92  ? 237 LYS A CB  1 
ATOM   1928 C  CG  . LYS A 1 241 ? 10.506  -23.243 -12.094 1   49.62  ? 237 LYS A CG  1 
ATOM   1929 C  CD  . LYS A 1 241 ? 11.683  -23.044 -11.136 1   57.05  ? 237 LYS A CD  1 
ATOM   1930 C  CE  . LYS A 1 241 ? 13.073  -23.404 -11.625 1   61.91  ? 237 LYS A CE  1 
ATOM   1931 N  NZ  . LYS A 1 241 ? 13.549  -22.784 -12.876 1   63.24  ? 237 LYS A NZ  1 
ATOM   1932 N  N   . PRO A 1 242 ? 9.491   -26.135 -15.789 1   40.83  ? 238 PRO A N   1 
ATOM   1933 C  CA  . PRO A 1 242 ? 9.749   -27.345 -16.574 1   40.69  ? 238 PRO A CA  1 
ATOM   1934 C  C   . PRO A 1 242 ? 10.819  -28.3   -16.038 1   40.53  ? 238 PRO A C   1 
ATOM   1935 O  O   . PRO A 1 242 ? 10.797  -29.481 -16.36  1   40.37  ? 238 PRO A O   1 
ATOM   1936 C  CB  . PRO A 1 242 ? 10.141  -26.799 -17.99  1   41.68  ? 238 PRO A CB  1 
ATOM   1937 C  CG  . PRO A 1 242 ? 10.44   -25.328 -17.755 1   41.06  ? 238 PRO A CG  1 
ATOM   1938 C  CD  . PRO A 1 242 ? 9.462   -24.935 -16.639 1   40.93  ? 238 PRO A CD  1 
ATOM   1939 N  N   . SER A 1 243 ? 11.776  -27.789 -15.253 1   40.3   ? 239 SER A N   1 
ATOM   1940 C  CA  . SER A 1 243 ? 12.892  -28.604 -14.786 1   40.17  ? 239 SER A CA  1 
ATOM   1941 C  C   . SER A 1 243 ? 12.532  -29.353 -13.497 1   36.89  ? 239 SER A C   1 
ATOM   1942 O  O   . SER A 1 243 ? 13.307  -30.145 -12.988 1   36.34  ? 239 SER A O   1 
ATOM   1943 C  CB  . SER A 1 243 ? 14.149  -27.785 -14.643 1   42     ? 239 SER A CB  1 
ATOM   1944 O  OG  . SER A 1 243 ? 13.84   -26.655 -13.84  1   44.01  ? 239 SER A OG  1 
ATOM   1945 N  N   . PHE A 1 244 ? 11.334  -29.124 -12.969 1   35.53  ? 240 PHE A N   1 
ATOM   1946 C  CA  . PHE A 1 244 ? 10.886  -29.912 -11.841 1   35.9   ? 240 PHE A CA  1 
ATOM   1947 C  C   . PHE A 1 244 ? 11.136  -31.39  -12.105 1   37.17  ? 240 PHE A C   1 
ATOM   1948 O  O   . PHE A 1 244 ? 10.857  -31.926 -13.185 1   37.63  ? 240 PHE A O   1 
ATOM   1949 C  CB  . PHE A 1 244 ? 9.387   -29.784 -11.623 1   35.75  ? 240 PHE A CB  1 
ATOM   1950 C  CG  . PHE A 1 244 ? 8.975   -28.534 -10.866 1   36.89  ? 240 PHE A CG  1 
ATOM   1951 C  CD1 . PHE A 1 244 ? 9.924   -27.727 -10.243 1   36.72  ? 240 PHE A CD1 1 
ATOM   1952 C  CD2 . PHE A 1 244 ? 7.633   -28.18  -10.773 1   35.61  ? 240 PHE A CD2 1 
ATOM   1953 C  CE1 . PHE A 1 244 ? 9.527   -26.591 -9.547  1   36.4   ? 240 PHE A CE1 1 
ATOM   1954 C  CE2 . PHE A 1 244 ? 7.256   -27.056 -10.053 1   36.2   ? 240 PHE A CE2 1 
ATOM   1955 C  CZ  . PHE A 1 244 ? 8.2     -26.264 -9.449  1   34.39  ? 240 PHE A CZ  1 
ATOM   1956 N  N   . PRO A 1 245 ? 11.683  -32.106 -11.111 1   37.25  ? 241 PRO A N   1 
ATOM   1957 C  CA  . PRO A 1 245 ? 11.923  -33.531 -11.277 1   38     ? 241 PRO A CA  1 
ATOM   1958 C  C   . PRO A 1 245 ? 10.548  -34.164 -11.448 1   36.99  ? 241 PRO A C   1 
ATOM   1959 O  O   . PRO A 1 245 ? 9.569   -33.67  -10.899 1   33.89  ? 241 PRO A O   1 
ATOM   1960 C  CB  . PRO A 1 245 ? 12.615  -33.884 -9.953  1   38.93  ? 241 PRO A CB  1 
ATOM   1961 C  CG  . PRO A 1 245 ? 13.256  -32.586 -9.529  1   38.03  ? 241 PRO A CG  1 
ATOM   1962 C  CD  . PRO A 1 245 ? 12.154  -31.581 -9.824  1   36.94  ? 241 PRO A CD  1 
ATOM   1963 N  N   . LYS A 1 246 ? 10.481  -35.222 -12.269 1   39.88  ? 242 LYS A N   1 
ATOM   1964 C  CA  . LYS A 1 246 ? 9.222   -35.899 -12.561 1   41.35  ? 242 LYS A CA  1 
ATOM   1965 C  C   . LYS A 1 246 ? 9.19    -37.206 -11.778 1   39.51  ? 242 LYS A C   1 
ATOM   1966 O  O   . LYS A 1 246 ? 9.819   -38.173 -12.192 1   40.28  ? 242 LYS A O   1 
ATOM   1967 C  CB  . LYS A 1 246 ? 9.088   -36.086 -14.078 1   42.56  ? 242 LYS A CB  1 
ATOM   1968 C  CG  . LYS A 1 246 ? 8.659   -34.797 -14.753 1   48.95  ? 242 LYS A CG  1 
ATOM   1969 C  CD  . LYS A 1 246 ? 8.161   -35.023 -16.176 1   57.74  ? 242 LYS A CD  1 
ATOM   1970 C  CE  . LYS A 1 246 ? 7.945   -33.784 -17     1   57.26  ? 242 LYS A CE  1 
ATOM   1971 N  NZ  . LYS A 1 246 ? 9.135   -33.527 -17.813 1   56.04  ? 242 LYS A NZ  1 
ATOM   1972 N  N   . TRP A 1 247 ? 8.607   -37.16  -10.594 1   35.69  ? 243 TRP A N   1 
ATOM   1973 C  CA  . TRP A 1 247 ? 8.544   -38.363 -9.743  1   35.75  ? 243 TRP A CA  1 
ATOM   1974 C  C   . TRP A 1 247 ? 7.268   -39.105 -10.077 1   37.14  ? 243 TRP A C   1 
ATOM   1975 O  O   . TRP A 1 247 ? 6.282   -38.477 -10.474 1   39.5   ? 243 TRP A O   1 
ATOM   1976 C  CB  . TRP A 1 247 ? 8.593   -37.984 -8.261  1   32.8   ? 243 TRP A CB  1 
ATOM   1977 C  CG  . TRP A 1 247 ? 9.916   -37.46  -7.78   1   33.8   ? 243 TRP A CG  1 
ATOM   1978 C  CD1 . TRP A 1 247 ? 11.036  -38.185 -7.506  1   35.01  ? 243 TRP A CD1 1 
ATOM   1979 C  CD2 . TRP A 1 247 ? 10.238  -36.089 -7.473  1   33.17  ? 243 TRP A CD2 1 
ATOM   1980 N  NE1 . TRP A 1 247 ? 12.035  -37.362 -7.065  1   36.79  ? 243 TRP A NE1 1 
ATOM   1981 C  CE2 . TRP A 1 247 ? 11.577  -36.073 -7.032  1   36.56  ? 243 TRP A CE2 1 
ATOM   1982 C  CE3 . TRP A 1 247 ? 9.532   -34.886 -7.528  1   31.27  ? 243 TRP A CE3 1 
ATOM   1983 C  CZ2 . TRP A 1 247 ? 12.216  -34.899 -6.646  1   35.14  ? 243 TRP A CZ2 1 
ATOM   1984 C  CZ3 . TRP A 1 247 ? 10.166  -33.727 -7.147  1   31.28  ? 243 TRP A CZ3 1 
ATOM   1985 C  CH2 . TRP A 1 247 ? 11.485  -33.737 -6.704  1   33.58  ? 243 TRP A CH2 1 
ATOM   1986 N  N   . ALA A 1 248 ? 7.306   -40.414 -9.926  1   39.52  ? 244 ALA A N   1 
ATOM   1987 C  CA  . ALA A 1 248 ? 6.126   -41.236 -10.235 1   39.32  ? 244 ALA A CA  1 
ATOM   1988 C  C   . ALA A 1 248 ? 5.222   -41.313 -9.012  1   38.73  ? 244 ALA A C   1 
ATOM   1989 O  O   . ALA A 1 248 ? 5.732   -41.252 -7.883  1   38.61  ? 244 ALA A O   1 
ATOM   1990 C  CB  . ALA A 1 248 ? 6.578   -42.598 -10.685 1   37.58  ? 244 ALA A CB  1 
ATOM   1991 N  N   . ARG A 1 249 ? 3.931   -41.399 -9.224  1   40.55  ? 245 ARG A N   1 
ATOM   1992 C  CA  . ARG A 1 249 ? 2.962   -41.526 -8.115  1   43.47  ? 245 ARG A CA  1 
ATOM   1993 C  C   . ARG A 1 249 ? 3.195   -42.875 -7.448  1   48.34  ? 245 ARG A C   1 
ATOM   1994 O  O   . ARG A 1 249 ? 3.333   -43.877 -8.16   1   52.02  ? 245 ARG A O   1 
ATOM   1995 C  CB  . ARG A 1 249 ? 1.531   -41.412 -8.645  1   41.81  ? 245 ARG A CB  1 
ATOM   1996 C  CG  . ARG A 1 249 ? 0.446   -41.409 -7.583  1   43.09  ? 245 ARG A CG  1 
ATOM   1997 C  CD  . ARG A 1 249 ? -0.907  -41.195 -8.215  1   46.51  ? 245 ARG A CD  1 
ATOM   1998 N  NE  . ARG A 1 249 ? -1.954  -41.216 -7.191  1   56.5   ? 245 ARG A NE  1 
ATOM   1999 C  CZ  . ARG A 1 249 ? -2.277  -40.174 -6.453  1   53.97  ? 245 ARG A CZ  1 
ATOM   2000 N  NH1 . ARG A 1 249 ? -3.502  -39.691 -6.504  1   59.23  ? 245 ARG A NH1 1 
ATOM   2001 N  NH2 . ARG A 1 249 ? -1.367  -39.612 -5.682  1   62.58  ? 245 ARG A NH2 1 
ATOM   2002 N  N   . GLN A 1 250 ? 3.244   -42.891 -6.146  1   57.98  ? 246 GLN A N   1 
ATOM   2003 C  CA  . GLN A 1 250 ? 3.521   -44.129 -5.385  1   61.27  ? 246 GLN A CA  1 
ATOM   2004 C  C   . GLN A 1 250 ? 2.194   -44.799 -5.029  1   59.35  ? 246 GLN A C   1 
ATOM   2005 O  O   . GLN A 1 250 ? 1.18    -44.082 -4.955  1   59.02  ? 246 GLN A O   1 
ATOM   2006 C  CB  . GLN A 1 250 ? 4.36    -43.748 -4.167  1   58.57  ? 246 GLN A CB  1 
ATOM   2007 C  CG  . GLN A 1 250 ? 3.569   -43.492 -2.89   1   65.07  ? 246 GLN A CG  1 
ATOM   2008 C  CD  . GLN A 1 250 ? 4.457   -43.191 -1.704  1   73.75  ? 246 GLN A CD  1 
ATOM   2009 O  OE1 . GLN A 1 250 ? 5.326   -42.315 -1.758  1   77.2   ? 246 GLN A OE1 1 
ATOM   2010 N  NE2 . GLN A 1 250 ? 4.255   -43.924 -0.62   1   73.14  ? 246 GLN A NE2 1 
ATOM   2011 N  N   . ASP A 1 251 ? 2.202   -46.124 -4.87   1   58.67  ? 247 ASP A N   1 
ATOM   2012 C  CA  . ASP A 1 251 ? 0.984   -46.827 -4.402  1   55.59  ? 247 ASP A CA  1 
ATOM   2013 C  C   . ASP A 1 251 ? 0.444   -46.006 -3.244  1   49.8   ? 247 ASP A C   1 
ATOM   2014 O  O   . ASP A 1 251 ? 1.174   -45.797 -2.271  1   52.87  ? 247 ASP A O   1 
ATOM   2015 C  CB  . ASP A 1 251 ? 1.283   -48.261 -4.006  1   64.97  ? 247 ASP A CB  1 
ATOM   2016 C  CG  . ASP A 1 251 ? 0.076   -49.149 -3.756  1   71.49  ? 247 ASP A CG  1 
ATOM   2017 O  OD1 . ASP A 1 251 ? -1.028  -48.778 -4.201  1   75.98  ? 247 ASP A OD1 1 
ATOM   2018 O  OD2 . ASP A 1 251 ? 0.256   -50.202 -3.113  1   68.97  ? 247 ASP A OD2 1 
ATOM   2019 N  N   . PHE A 1 252 ? -0.782  -45.537 -3.368  1   43.19  ? 248 PHE A N   1 
ATOM   2020 C  CA  . PHE A 1 252 ? -1.317  -44.665 -2.344  1   40.07  ? 248 PHE A CA  1 
ATOM   2021 C  C   . PHE A 1 252 ? -1.551  -45.434 -1.047  1   40.87  ? 248 PHE A C   1 
ATOM   2022 O  O   . PHE A 1 252 ? -1.662  -44.839 0.028   1   42.11  ? 248 PHE A O   1 
ATOM   2023 C  CB  . PHE A 1 252 ? -2.603  -44.033 -2.88   1   43.19  ? 248 PHE A CB  1 
ATOM   2024 C  CG  . PHE A 1 252 ? -2.986  -42.754 -2.15   1   40.26  ? 248 PHE A CG  1 
ATOM   2025 C  CD1 . PHE A 1 252 ? -3.655  -42.793 -0.937  1   39.59  ? 248 PHE A CD1 1 
ATOM   2026 C  CD2 . PHE A 1 252 ? -2.638  -41.513 -2.67   1   38.83  ? 248 PHE A CD2 1 
ATOM   2027 C  CE1 . PHE A 1 252 ? -3.969  -41.607 -0.276  1   38.97  ? 248 PHE A CE1 1 
ATOM   2028 C  CE2 . PHE A 1 252 ? -2.958  -40.341 -2.011  1   35.87  ? 248 PHE A CE2 1 
ATOM   2029 C  CZ  . PHE A 1 252 ? -3.608  -40.39  -0.802  1   35.73  ? 248 PHE A CZ  1 
ATOM   2030 N  N   . SER A 1 253 ? -1.648  -46.766 -1.149  1   44.38  ? 249 SER A N   1 
ATOM   2031 C  CA  . SER A 1 253 ? -1.75   -47.585 0.051   1   43.74  ? 249 SER A CA  1 
ATOM   2032 C  C   . SER A 1 253 ? -0.479  -47.408 0.877   1   46.9   ? 249 SER A C   1 
ATOM   2033 O  O   . SER A 1 253 ? -0.499  -47.578 2.086   1   51.45  ? 249 SER A O   1 
ATOM   2034 C  CB  . SER A 1 253 ? -2.003  -49.028 -0.268  1   40.23  ? 249 SER A CB  1 
ATOM   2035 O  OG  . SER A 1 253 ? -0.889  -49.56  -0.953  1   41.78  ? 249 SER A OG  1 
ATOM   2036 N  N   . LYS A 1 254 ? 0.61    -47.003 0.215   1   47.47  ? 250 LYS A N   1 
ATOM   2037 C  CA  . LYS A 1 254 ? 1.919   -46.851 0.832   1   46.44  ? 250 LYS A CA  1 
ATOM   2038 C  C   . LYS A 1 254 ? 2.058   -45.497 1.52    1   47.14  ? 250 LYS A C   1 
ATOM   2039 O  O   . LYS A 1 254 ? 2.996   -45.302 2.271   1   55.04  ? 250 LYS A O   1 
ATOM   2040 C  CB  . LYS A 1 254 ? 3.018   -47.126 -0.196  1   47.16  ? 250 LYS A CB  1 
ATOM   2041 C  CG  . LYS A 1 254 ? 3.034   -48.593 -0.649  1   47.47  ? 250 LYS A CG  1 
ATOM   2042 C  CD  . LYS A 1 254 ? 3.504   -49.576 0.417   1   46.66  ? 250 LYS A CD  1 
ATOM   2043 C  CE  . LYS A 1 254 ? 3.236   -50.956 -0.042  1   47.07  ? 250 LYS A CE  1 
ATOM   2044 N  NZ  . LYS A 1 254 ? 1.848   -51.27  0.281   1   46.18  ? 250 LYS A NZ  1 
ATOM   2045 N  N   . VAL A 1 255 ? 1.108   -44.588 1.312   1   44.46  ? 251 VAL A N   1 
ATOM   2046 C  CA  . VAL A 1 255 ? 1.187   -43.268 1.905   1   43.12  ? 251 VAL A CA  1 
ATOM   2047 C  C   . VAL A 1 255 ? 0.711   -43.322 3.354   1   45.63  ? 251 VAL A C   1 
ATOM   2048 O  O   . VAL A 1 255 ? 1.173   -42.544 4.185   1   52.59  ? 251 VAL A O   1 
ATOM   2049 C  CB  . VAL A 1 255 ? 0.373   -42.246 1.088   1   40.81  ? 251 VAL A CB  1 
ATOM   2050 C  CG1 . VAL A 1 255 ? 0.271   -40.892 1.785   1   39.22  ? 251 VAL A CG1 1 
ATOM   2051 C  CG2 . VAL A 1 255 ? 0.958   -42.083 -0.308  1   43.65  ? 251 VAL A CG2 1 
ATOM   2052 N  N   . VAL A 1 256 ? -0.272  -44.18  3.637   1   44.11  ? 252 VAL A N   1 
ATOM   2053 C  CA  . VAL A 1 256 ? -0.831  -44.284 4.97    1   39.97  ? 252 VAL A CA  1 
ATOM   2054 C  C   . VAL A 1 256 ? -1.164  -45.751 5.206   1   41.04  ? 252 VAL A C   1 
ATOM   2055 O  O   . VAL A 1 256 ? -2.332  -46.159 5.269   1   42.92  ? 252 VAL A O   1 
ATOM   2056 C  CB  . VAL A 1 256 ? -2.018  -43.342 5.232   1   43.43  ? 252 VAL A CB  1 
ATOM   2057 C  CG1 . VAL A 1 256 ? -2.414  -43.356 6.701   1   47.15  ? 252 VAL A CG1 1 
ATOM   2058 C  CG2 . VAL A 1 256 ? -1.694  -41.908 4.849   1   43.12  ? 252 VAL A CG2 1 
ATOM   2059 N  N   . PRO A 1 257 ? -0.122  -46.599 5.347   1   38.67  ? 253 PRO A N   1 
ATOM   2060 C  CA  . PRO A 1 257 ? -0.309  -48.035 5.237   1   38.67  ? 253 PRO A CA  1 
ATOM   2061 C  C   . PRO A 1 257 ? -1.434  -48.628 6.076   1   39.43  ? 253 PRO A C   1 
ATOM   2062 O  O   . PRO A 1 257 ? -2.061  -49.577 5.625   1   40.67  ? 253 PRO A O   1 
ATOM   2063 C  CB  . PRO A 1 257 ? 1.077   -48.608 5.578   1   39.76  ? 253 PRO A CB  1 
ATOM   2064 C  CG  . PRO A 1 257 ? 2.024   -47.492 5.246   1   38.32  ? 253 PRO A CG  1 
ATOM   2065 C  CD  . PRO A 1 257 ? 1.279   -46.226 5.609   1   36.98  ? 253 PRO A CD  1 
ATOM   2066 N  N   . PRO A 1 258 ? -1.672  -48.192 7.333   1   40.21  ? 254 PRO A N   1 
ATOM   2067 C  CA  . PRO A 1 258 ? -2.737  -48.802 8.134   1   43.44  ? 254 PRO A CA  1 
ATOM   2068 C  C   . PRO A 1 258 ? -4.167  -48.439 7.729   1   42.59  ? 254 PRO A C   1 
ATOM   2069 O  O   . PRO A 1 258 ? -5.115  -49.083 8.194   1   41.36  ? 254 PRO A O   1 
ATOM   2070 C  CB  . PRO A 1 258 ? -2.411  -48.421 9.597   1   40.64  ? 254 PRO A CB  1 
ATOM   2071 C  CG  . PRO A 1 258 ? -1.629  -47.139 9.451   1   38.59  ? 254 PRO A CG  1 
ATOM   2072 C  CD  . PRO A 1 258 ? -0.908  -47.192 8.101   1   38.44  ? 254 PRO A CD  1 
ATOM   2073 N  N   . LEU A 1 259 ? -4.31   -47.427 6.856   1   41.6   ? 255 LEU A N   1 
ATOM   2074 C  CA  . LEU A 1 259 ? -5.638  -46.979 6.455   1   42.43  ? 255 LEU A CA  1 
ATOM   2075 C  C   . LEU A 1 259 ? -6.22   -48.035 5.524   1   47.28  ? 255 LEU A C   1 
ATOM   2076 O  O   . LEU A 1 259 ? -5.471  -48.617 4.736   1   44.59  ? 255 LEU A O   1 
ATOM   2077 C  CB  . LEU A 1 259 ? -5.46   -45.659 5.722   1   44.03  ? 255 LEU A CB  1 
ATOM   2078 C  CG  . LEU A 1 259 ? -6.556  -44.617 5.898   1   44.49  ? 255 LEU A CG  1 
ATOM   2079 C  CD1 . LEU A 1 259 ? -6.903  -44.412 7.349   1   43.85  ? 255 LEU A CD1 1 
ATOM   2080 C  CD2 . LEU A 1 259 ? -6.01   -43.355 5.296   1   42.74  ? 255 LEU A CD2 1 
ATOM   2081 N  N   . ASP A 1 260 ? -7.531  -48.315 5.658   1   54.11  ? 256 ASP A N   1 
ATOM   2082 C  CA  . ASP A 1 260 ? -8.196  -49.309 4.825   1   56.45  ? 256 ASP A CA  1 
ATOM   2083 C  C   . ASP A 1 260 ? -8.742  -48.614 3.583   1   50.71  ? 256 ASP A C   1 
ATOM   2084 O  O   . ASP A 1 260 ? -8.535  -47.418 3.419   1   46.66  ? 256 ASP A O   1 
ATOM   2085 C  CB  . ASP A 1 260 ? -9.161  -50.181 5.616   1   71.22  ? 256 ASP A CB  1 
ATOM   2086 C  CG  . ASP A 1 260 ? -8.543  -50.979 6.767   1   87.23  ? 256 ASP A CG  1 
ATOM   2087 O  OD1 . ASP A 1 260 ? -7.387  -51.477 6.616   1   80.69  ? 256 ASP A OD1 1 
ATOM   2088 O  OD2 . ASP A 1 260 ? -9.227  -51.112 7.814   1   88.13  ? 256 ASP A OD2 1 
ATOM   2089 N  N   . GLU A 1 261 ? -9.416  -49.373 2.713   1   50.95  ? 257 GLU A N   1 
ATOM   2090 C  CA  . GLU A 1 261 ? -9.821  -48.923 1.393   1   47.89  ? 257 GLU A CA  1 
ATOM   2091 C  C   . GLU A 1 261 ? -10.667 -47.642 1.443   1   45.8   ? 257 GLU A C   1 
ATOM   2092 O  O   . GLU A 1 261 ? -10.521 -46.774 0.584   1   42.4   ? 257 GLU A O   1 
ATOM   2093 C  CB  . GLU A 1 261 ? -10.55  -50.092 0.741   1   55.57  ? 257 GLU A CB  1 
ATOM   2094 C  CG  . GLU A 1 261 ? -10.692 -49.918 -0.768  1   65.93  ? 257 GLU A CG  1 
ATOM   2095 C  CD  . GLU A 1 261 ? -11.46  -51.07  -1.393  1   73.07  ? 257 GLU A CD  1 
ATOM   2096 O  OE1 . GLU A 1 261 ? -12.52  -50.795 -1.982  1   73.93  ? 257 GLU A OE1 1 
ATOM   2097 O  OE2 . GLU A 1 261 ? -11.016 -52.232 -1.274  1   76.48  ? 257 GLU A OE2 1 
ATOM   2098 N  N   . ASP A 1 262 ? -11.566 -47.509 2.433   1   42.87  ? 258 ASP A N   1 
ATOM   2099 C  CA  . ASP A 1 262 ? -12.444 -46.351 2.474   1   38.36  ? 258 ASP A CA  1 
ATOM   2100 C  C   . ASP A 1 262 ? -11.628 -45.124 2.86    1   38.5   ? 258 ASP A C   1 
ATOM   2101 O  O   . ASP A 1 262 ? -11.726 -44.085 2.204   1   35.77  ? 258 ASP A O   1 
ATOM   2102 C  CB  . ASP A 1 262 ? -13.632 -46.572 3.393   1   40.32  ? 258 ASP A CB  1 
ATOM   2103 C  CG  . ASP A 1 262 ? -14.739 -47.502 2.888   1   44.27  ? 258 ASP A CG  1 
ATOM   2104 O  OD1 . ASP A 1 262 ? -14.847 -47.709 1.66    1   42.98  ? 258 ASP A OD1 1 
ATOM   2105 O  OD2 . ASP A 1 262 ? -15.49  -48.041 3.744   1   46.34  ? 258 ASP A OD2 1 
ATOM   2106 N  N   . GLY A 1 263 ? -10.848 -45.245 3.949   1   38.08  ? 259 GLY A N   1 
ATOM   2107 C  CA  . GLY A 1 263 ? -9.971  -44.173 4.386   1   32.17  ? 259 GLY A CA  1 
ATOM   2108 C  C   . GLY A 1 263 ? -9.08   -43.731 3.233   1   33.6   ? 259 GLY A C   1 
ATOM   2109 O  O   . GLY A 1 263 ? -8.946  -42.533 2.997   1   34.59  ? 259 GLY A O   1 
ATOM   2110 N  N   . ARG A 1 264 ? -8.538  -44.695 2.47    1   32.78  ? 260 ARG A N   1 
ATOM   2111 C  CA  . ARG A 1 264 ? -7.635  -44.366 1.38    1   33.55  ? 260 ARG A CA  1 
ATOM   2112 C  C   . ARG A 1 264 ? -8.385  -43.615 0.285   1   33.09  ? 260 ARG A C   1 
ATOM   2113 O  O   . ARG A 1 264 ? -7.852  -42.664 -0.264  1   32.39  ? 260 ARG A O   1 
ATOM   2114 C  CB  . ARG A 1 264 ? -6.981  -45.566 0.692   1   35.41  ? 260 ARG A CB  1 
ATOM   2115 C  CG  . ARG A 1 264 ? -5.91   -46.262 1.513   1   40.79  ? 260 ARG A CG  1 
ATOM   2116 C  CD  . ARG A 1 264 ? -5.041  -47.166 0.625   1   44.29  ? 260 ARG A CD  1 
ATOM   2117 N  NE  . ARG A 1 264 ? -5.761  -48.245 -0.057  1   43.71  ? 260 ARG A NE  1 
ATOM   2118 C  CZ  . ARG A 1 264 ? -6.144  -49.358 0.535   1   45.06  ? 260 ARG A CZ  1 
ATOM   2119 N  NH1 . ARG A 1 264 ? -5.819  -49.592 1.796   1   43.84  ? 260 ARG A NH1 1 
ATOM   2120 N  NH2 . ARG A 1 264 ? -6.812  -50.267 -0.156  1   48     ? 260 ARG A NH2 1 
ATOM   2121 N  N   . SER A 1 265 ? -9.584  -44.096 -0.061  1   33.47  ? 261 SER A N   1 
ATOM   2122 C  CA  . SER A 1 265 ? -10.399 -43.474 -1.086  1   33.63  ? 261 SER A CA  1 
ATOM   2123 C  C   . SER A 1 265 ? -10.591 -42.005 -0.716  1   33.37  ? 261 SER A C   1 
ATOM   2124 O  O   . SER A 1 265 ? -10.28  -41.104 -1.502  1   33.12  ? 261 SER A O   1 
ATOM   2125 C  CB  . SER A 1 265 ? -11.702 -44.216 -1.235  1   33.17  ? 261 SER A CB  1 
ATOM   2126 O  OG  . SER A 1 265 ? -12.74  -43.413 -1.764  1   33.64  ? 261 SER A OG  1 
ATOM   2127 N  N   . LEU A 1 266 ? -10.995 -41.775 0.539   1   33.21  ? 262 LEU A N   1 
ATOM   2128 C  CA  . LEU A 1 266 ? -11.327 -40.428 0.981   1   33.17  ? 262 LEU A CA  1 
ATOM   2129 C  C   . LEU A 1 266 ? -10.074 -39.55  0.974   1   36.13  ? 262 LEU A C   1 
ATOM   2130 O  O   . LEU A 1 266 ? -10.14  -38.412 0.472   1   36.61  ? 262 LEU A O   1 
ATOM   2131 C  CB  . LEU A 1 266 ? -12.01  -40.454 2.348   1   31.48  ? 262 LEU A CB  1 
ATOM   2132 C  CG  . LEU A 1 266 ? -12.188 -39.108 3.057   1   31.26  ? 262 LEU A CG  1 
ATOM   2133 C  CD1 . LEU A 1 266 ? -12.998 -38.076 2.229   1   27.79  ? 262 LEU A CD1 1 
ATOM   2134 C  CD2 . LEU A 1 266 ? -12.84  -39.401 4.405   1   29.23  ? 262 LEU A CD2 1 
ATOM   2135 N  N   . LEU A 1 267 ? -8.963  -40.076 1.544   1   32.2   ? 263 LEU A N   1 
ATOM   2136 C  CA  . LEU A 1 267 ? -7.748  -39.294 1.684   1   31.83  ? 263 LEU A CA  1 
ATOM   2137 C  C   . LEU A 1 267 ? -7.294  -38.849 0.298   1   35.11  ? 263 LEU A C   1 
ATOM   2138 O  O   . LEU A 1 267 ? -6.981  -37.665 0.128   1   38.55  ? 263 LEU A O   1 
ATOM   2139 C  CB  . LEU A 1 267 ? -6.614  -39.972 2.453   1   32.84  ? 263 LEU A CB  1 
ATOM   2140 C  CG  . LEU A 1 267 ? -5.288  -39.198 2.562   1   30.18  ? 263 LEU A CG  1 
ATOM   2141 C  CD1 . LEU A 1 267 ? -5.371  -37.982 3.467   1   28.99  ? 263 LEU A CD1 1 
ATOM   2142 C  CD2 . LEU A 1 267 ? -4.187  -40.1   3.067   1   31.82  ? 263 LEU A CD2 1 
ATOM   2143 N  N   . SER A 1 268 ? -7.303  -39.781 -0.675  1   31.85  ? 264 SER A N   1 
ATOM   2144 C  CA  . SER A 1 268 ? -6.887  -39.486 -2.042  1   33.52  ? 264 SER A CA  1 
ATOM   2145 C  C   . SER A 1 268 ? -7.726  -38.38  -2.673  1   34.55  ? 264 SER A C   1 
ATOM   2146 O  O   . SER A 1 268 ? -7.234  -37.668 -3.541  1   36.4   ? 264 SER A O   1 
ATOM   2147 C  CB  . SER A 1 268 ? -6.893  -40.694 -2.939  1   34.85  ? 264 SER A CB  1 
ATOM   2148 O  OG  . SER A 1 268 ? -8.234  -41.099 -3.167  1   42.1   ? 264 SER A OG  1 
ATOM   2149 N  N   . GLN A 1 269 ? -8.997  -38.26  -2.276  1   33.98  ? 265 GLN A N   1 
ATOM   2150 C  CA  . GLN A 1 269 ? -9.839  -37.254 -2.899  1   32.86  ? 265 GLN A CA  1 
ATOM   2151 C  C   . GLN A 1 269 ? -9.633  -35.915 -2.204  1   32.93  ? 265 GLN A C   1 
ATOM   2152 O  O   . GLN A 1 269 ? -9.963  -34.864 -2.746  1   37.17  ? 265 GLN A O   1 
ATOM   2153 C  CB  . GLN A 1 269 ? -11.307 -37.656 -2.859  1   34.63  ? 265 GLN A CB  1 
ATOM   2154 C  CG  . GLN A 1 269 ? -11.638 -38.846 -3.749  1   37.42  ? 265 GLN A CG  1 
ATOM   2155 C  CD  . GLN A 1 269 ? -13.082 -39.288 -3.641  1   43.51  ? 265 GLN A CD  1 
ATOM   2156 O  OE1 . GLN A 1 269 ? -13.39  -40.344 -3.069  1   49.07  ? 265 GLN A OE1 1 
ATOM   2157 N  NE2 . GLN A 1 269 ? -13.998 -38.487 -4.18   1   43.24  ? 265 GLN A NE2 1 
ATOM   2158 N  N   . MET A 1 270 ? -9.078  -35.952 -0.996  1   31.62  ? 266 MET A N   1 
ATOM   2159 C  CA  . MET A 1 270 ? -8.721  -34.716 -0.327  1   32.43  ? 266 MET A CA  1 
ATOM   2160 C  C   . MET A 1 270 ? -7.41   -34.139 -0.89   1   36.17  ? 266 MET A C   1 
ATOM   2161 O  O   . MET A 1 270 ? -7.254  -32.919 -0.956  1   39.33  ? 266 MET A O   1 
ATOM   2162 C  CB  . MET A 1 270 ? -8.706  -34.891 1.195   1   27.1   ? 266 MET A CB  1 
ATOM   2163 C  CG  . MET A 1 270 ? -10.054 -35.28  1.686   1   27     ? 266 MET A CG  1 
ATOM   2164 S  SD  . MET A 1 270 ? -10.097 -35.647 3.449   1   33.59  ? 266 MET A SD  1 
ATOM   2165 C  CE  . MET A 1 270 ? -10.102 -33.982 4.126   1   29.2   ? 266 MET A CE  1 
ATOM   2166 N  N   . LEU A 1 271 ? -6.489  -35.006 -1.328  1   33.47  ? 267 LEU A N   1 
ATOM   2167 C  CA  . LEU A 1 271 ? -5.175  -34.572 -1.762  1   32.3   ? 267 LEU A CA  1 
ATOM   2168 C  C   . LEU A 1 271 ? -5.074  -34.666 -3.282  1   35.87  ? 267 LEU A C   1 
ATOM   2169 O  O   . LEU A 1 271 ? -3.972  -34.844 -3.795  1   35.38  ? 267 LEU A O   1 
ATOM   2170 C  CB  . LEU A 1 271 ? -4.138  -35.489 -1.124  1   29.09  ? 267 LEU A CB  1 
ATOM   2171 C  CG  . LEU A 1 271 ? -4.142  -35.602 0.395   1   27.69  ? 267 LEU A CG  1 
ATOM   2172 C  CD1 . LEU A 1 271 ? -3.175  -36.707 0.737   1   28.38  ? 267 LEU A CD1 1 
ATOM   2173 C  CD2 . LEU A 1 271 ? -3.671  -34.307 1.011   1   26.89  ? 267 LEU A CD2 1 
ATOM   2174 N  N   . HIS A 1 272 ? -6.216  -34.613 -3.982  1   33.8   ? 268 HIS A N   1 
ATOM   2175 C  CA  . HIS A 1 272 ? -6.212  -34.508 -5.433  1   39.13  ? 268 HIS A CA  1 
ATOM   2176 C  C   . HIS A 1 272 ? -5.434  -33.25  -5.876  1   38.04  ? 268 HIS A C   1 
ATOM   2177 O  O   . HIS A 1 272 ? -5.617  -32.15  -5.336  1   36.94  ? 268 HIS A O   1 
ATOM   2178 C  CB  . HIS A 1 272 ? -7.659  -34.641 -5.925  1   40.78  ? 268 HIS A CB  1 
ATOM   2179 C  CG  . HIS A 1 272 ? -7.825  -35.038 -7.351  1   50.53  ? 268 HIS A CG  1 
ATOM   2180 N  ND1 . HIS A 1 272 ? -7.144  -34.45  -8.409  1   61.99  ? 268 HIS A ND1 1 
ATOM   2181 C  CD2 . HIS A 1 272 ? -8.645  -35.946 -7.906  1   56.82  ? 268 HIS A CD2 1 
ATOM   2182 C  CE1 . HIS A 1 272 ? -7.53   -34.987 -9.568  1   55.9   ? 268 HIS A CE1 1 
ATOM   2183 N  NE2 . HIS A 1 272 ? -8.459  -35.884 -9.294  1   58.47  ? 268 HIS A NE2 1 
ATOM   2184 N  N   . TYR A 1 273 ? -4.521  -33.392 -6.846  1   34.62  ? 269 TYR A N   1 
ATOM   2185 C  CA  . TYR A 1 273 ? -3.81   -32.209 -7.319  1   34.57  ? 269 TYR A CA  1 
ATOM   2186 C  C   . TYR A 1 273 ? -4.767  -31.111 -7.806  1   36.74  ? 269 TYR A C   1 
ATOM   2187 O  O   . TYR A 1 273 ? -4.641  -29.949 -7.397  1   38.75  ? 269 TYR A O   1 
ATOM   2188 C  CB  . TYR A 1 273 ? -2.826  -32.471 -8.456  1   32.19  ? 269 TYR A CB  1 
ATOM   2189 C  CG  . TYR A 1 273 ? -1.503  -32.929 -7.9    1   32.79  ? 269 TYR A CG  1 
ATOM   2190 C  CD1 . TYR A 1 273 ? -0.746  -32.068 -7.119  1   34.31  ? 269 TYR A CD1 1 
ATOM   2191 C  CD2 . TYR A 1 273 ? -1.018  -34.21  -8.134  1   33.78  ? 269 TYR A CD2 1 
ATOM   2192 C  CE1 . TYR A 1 273 ? 0.456   -32.48  -6.575  1   34.3   ? 269 TYR A CE1 1 
ATOM   2193 C  CE2 . TYR A 1 273 ? 0.192   -34.63  -7.599  1   34.44  ? 269 TYR A CE2 1 
ATOM   2194 C  CZ  . TYR A 1 273 ? 0.938   -33.753 -6.828  1   35.05  ? 269 TYR A CZ  1 
ATOM   2195 O  OH  . TYR A 1 273 ? 2.132   -34.122 -6.272  1   38.42  ? 269 TYR A OH  1 
ATOM   2196 N  N   . ASP A 1 274 ? -5.685  -31.461 -8.723  1   33.2   ? 270 ASP A N   1 
ATOM   2197 C  CA  . ASP A 1 274 ? -6.506  -30.448 -9.368  1   33.86  ? 270 ASP A CA  1 
ATOM   2198 C  C   . ASP A 1 274 ? -7.558  -29.889 -8.403  1   33.99  ? 270 ASP A C   1 
ATOM   2199 O  O   . ASP A 1 274 ? -8.447  -30.612 -7.971  1   36.12  ? 270 ASP A O   1 
ATOM   2200 C  CB  . ASP A 1 274 ? -7.109  -31.043 -10.624 1   35.91  ? 270 ASP A CB  1 
ATOM   2201 C  CG  . ASP A 1 274 ? -7.973  -30.091 -11.422 1   36.89  ? 270 ASP A CG  1 
ATOM   2202 O  OD1 . ASP A 1 274 ? -8.178  -28.941 -10.964 1   37.49  ? 270 ASP A OD1 1 
ATOM   2203 O  OD2 . ASP A 1 274 ? -8.44   -30.524 -12.481 1   42.13  ? 270 ASP A OD2 1 
ATOM   2204 N  N   . PRO A 1 275 ? -7.564  -28.584 -8.035  1   35.24  ? 271 PRO A N   1 
ATOM   2205 C  CA  . PRO A 1 275 ? -8.524  -28.095 -7.037  1   31.64  ? 271 PRO A CA  1 
ATOM   2206 C  C   . PRO A 1 275 ? -9.979  -28.243 -7.473  1   34.31  ? 271 PRO A C   1 
ATOM   2207 O  O   . PRO A 1 275 ? -10.886 -28.213 -6.628  1   33.18  ? 271 PRO A O   1 
ATOM   2208 C  CB  . PRO A 1 275 ? -8.146  -26.647 -6.854  1   30.65  ? 271 PRO A CB  1 
ATOM   2209 C  CG  . PRO A 1 275 ? -6.717  -26.6   -7.295  1   33.2   ? 271 PRO A CG  1 
ATOM   2210 C  CD  . PRO A 1 275 ? -6.666  -27.527 -8.523  1   34.54  ? 271 PRO A CD  1 
ATOM   2211 N  N   . ASN A 1 276 ? -10.188 -28.418 -8.791  1   35.12  ? 272 ASN A N   1 
ATOM   2212 C  CA  . ASN A 1 276 ? -11.527 -28.634 -9.319  1   36.43  ? 272 ASN A CA  1 
ATOM   2213 C  C   . ASN A 1 276 ? -12.021 -30.034 -8.971  1   36     ? 272 ASN A C   1 
ATOM   2214 O  O   . ASN A 1 276 ? -13.208 -30.194 -8.74   1   35.64  ? 272 ASN A O   1 
ATOM   2215 C  CB  . ASN A 1 276 ? -11.626 -28.414 -10.821 1   37.77  ? 272 ASN A CB  1 
ATOM   2216 C  CG  . ASN A 1 276 ? -11.324 -26.985 -11.208 1   42.25  ? 272 ASN A CG  1 
ATOM   2217 O  OD1 . ASN A 1 276 ? -11.729 -26.055 -10.496 1   38.37  ? 272 ASN A OD1 1 
ATOM   2218 N  ND2 . ASN A 1 276 ? -10.597 -26.795 -12.309 1   40.8   ? 272 ASN A ND2 1 
ATOM   2219 N  N   . LYS A 1 277 ? -11.127 -31.03  -8.923  1   36.6   ? 273 LYS A N   1 
ATOM   2220 C  CA  . LYS A 1 277 ? -11.533 -32.404 -8.67   1   39.83  ? 273 LYS A CA  1 
ATOM   2221 C  C   . LYS A 1 277 ? -11.449 -32.739 -7.181  1   36.72  ? 273 LYS A C   1 
ATOM   2222 O  O   . LYS A 1 277 ? -12.015 -33.73  -6.755  1   36.16  ? 273 LYS A O   1 
ATOM   2223 C  CB  . LYS A 1 277 ? -10.708 -33.41  -9.479  1   46.12  ? 273 LYS A CB  1 
ATOM   2224 C  CG  . LYS A 1 277 ? -10.907 -33.285 -10.977 1   59.22  ? 273 LYS A CG  1 
ATOM   2225 C  CD  . LYS A 1 277 ? -10.334 -34.374 -11.882 1   69.66  ? 273 LYS A CD  1 
ATOM   2226 C  CE  . LYS A 1 277 ? -11.104 -34.258 -13.183 1   78.53  ? 273 LYS A CE  1 
ATOM   2227 N  NZ  . LYS A 1 277 ? -10.394 -34.723 -14.383 1   79.77  ? 273 LYS A NZ  1 
ATOM   2228 N  N   . ARG A 1 278 ? -10.721 -31.946 -6.384  1   35.52  ? 274 ARG A N   1 
ATOM   2229 C  CA  . ARG A 1 278 ? -10.6   -32.223 -4.957  1   33.24  ? 274 ARG A CA  1 
ATOM   2230 C  C   . ARG A 1 278 ? -11.988 -32.226 -4.303  1   32.49  ? 274 ARG A C   1 
ATOM   2231 O  O   . ARG A 1 278 ? -12.839 -31.39  -4.624  1   31.96  ? 274 ARG A O   1 
ATOM   2232 C  CB  . ARG A 1 278 ? -9.725  -31.114 -4.387  1   33.23  ? 274 ARG A CB  1 
ATOM   2233 C  CG  . ARG A 1 278 ? -8.89   -31.608 -3.219  1   34.9   ? 274 ARG A CG  1 
ATOM   2234 C  CD  . ARG A 1 278 ? -8.027  -30.449 -2.692  1   32.28  ? 274 ARG A CD  1 
ATOM   2235 N  NE  . ARG A 1 278 ? -6.929  -30.221 -3.633  1   29.35  ? 274 ARG A NE  1 
ATOM   2236 C  CZ  . ARG A 1 278 ? -6.219  -29.093 -3.705  1   30.12  ? 274 ARG A CZ  1 
ATOM   2237 N  NH1 . ARG A 1 278 ? -6.442  -28.116 -2.836  1   26.68  ? 274 ARG A NH1 1 
ATOM   2238 N  NH2 . ARG A 1 278 ? -5.306  -28.943 -4.667  1   28.11  ? 274 ARG A NH2 1 
ATOM   2239 N  N   . ILE A 1 279 ? -12.229 -33.202 -3.42   1   28.66  ? 275 ILE A N   1 
ATOM   2240 C  CA  . ILE A 1 279 ? -13.526 -33.372 -2.777  1   29.86  ? 275 ILE A CA  1 
ATOM   2241 C  C   . ILE A 1 279 ? -13.866 -32.121 -1.953  1   30.37  ? 275 ILE A C   1 
ATOM   2242 O  O   . ILE A 1 279 ? -12.963 -31.481 -1.394  1   30.34  ? 275 ILE A O   1 
ATOM   2243 C  CB  . ILE A 1 279 ? -13.559 -34.653 -1.921  1   27.56  ? 275 ILE A CB  1 
ATOM   2244 C  CG1 . ILE A 1 279 ? -14.992 -35.058 -1.575  1   28.41  ? 275 ILE A CG1 1 
ATOM   2245 C  CG2 . ILE A 1 279 ? -12.722 -34.456 -0.66   1   25.35  ? 275 ILE A CG2 1 
ATOM   2246 C  CD1 . ILE A 1 279 ? -15.164 -36.5   -1.136  1   27.09  ? 275 ILE A CD1 1 
ATOM   2247 N  N   . SER A 1 280 ? -15.163 -31.773 -1.897  1   27.56  ? 276 SER A N   1 
ATOM   2248 C  CA  . SER A 1 280 ? -15.636 -30.688 -1.042  1   29.05  ? 276 SER A CA  1 
ATOM   2249 C  C   . SER A 1 280 ? -15.935 -31.234 0.363   1   28.96  ? 276 SER A C   1 
ATOM   2250 O  O   . SER A 1 280 ? -16.256 -32.423 0.482   1   26.99  ? 276 SER A O   1 
ATOM   2251 C  CB  . SER A 1 280 ? -16.882 -30.078 -1.625  1   30.46  ? 276 SER A CB  1 
ATOM   2252 O  OG  . SER A 1 280 ? -17.999 -30.928 -1.372  1   32.29  ? 276 SER A OG  1 
ATOM   2253 N  N   . ALA A 1 281 ? -15.893 -30.365 1.405   1   28.08  ? 277 ALA A N   1 
ATOM   2254 C  CA  . ALA A 1 281 ? -16.253 -30.748 2.77    1   26.13  ? 277 ALA A CA  1 
ATOM   2255 C  C   . ALA A 1 281 ? -17.647 -31.361 2.785   1   30.1   ? 277 ALA A C   1 
ATOM   2256 O  O   . ALA A 1 281 ? -17.89  -32.366 3.441   1   34.72  ? 277 ALA A O   1 
ATOM   2257 C  CB  . ALA A 1 281 ? -16.245 -29.551 3.662   1   24.44  ? 277 ALA A CB  1 
ATOM   2258 N  N   . LYS A 1 282 ? -18.561 -30.743 2.041   1   32.34  ? 278 LYS A N   1 
ATOM   2259 C  CA  . LYS A 1 282 ? -19.96  -31.133 1.992   1   31.94  ? 278 LYS A CA  1 
ATOM   2260 C  C   . LYS A 1 282 ? -20.094 -32.56  1.455   1   33.64  ? 278 LYS A C   1 
ATOM   2261 O  O   . LYS A 1 282 ? -20.817 -33.396 2.02    1   31.9   ? 278 LYS A O   1 
ATOM   2262 C  CB  . LYS A 1 282 ? -20.663 -30.043 1.171   1   30.85  ? 278 LYS A CB  1 
ATOM   2263 C  CG  . LYS A 1 282 ? -22.149 -30.087 1.085   1   32.97  ? 278 LYS A CG  1 
ATOM   2264 C  CD  . LYS A 1 282 ? -22.648 -28.989 0.146   1   36.63  ? 278 LYS A CD  1 
ATOM   2265 C  CE  . LYS A 1 282 ? -23.055 -27.729 0.852   1   38.18  ? 278 LYS A CE  1 
ATOM   2266 N  NZ  . LYS A 1 282 ? -23.936 -26.9   0.032   1   35.97  ? 278 LYS A NZ  1 
ATOM   2267 N  N   . ALA A 1 283 ? -19.402 -32.842 0.345   1   38.11  ? 279 ALA A N   1 
ATOM   2268 C  CA  . ALA A 1 283 ? -19.456 -34.189 -0.247  1   39.09  ? 279 ALA A CA  1 
ATOM   2269 C  C   . ALA A 1 283 ? -18.696 -35.235 0.593   1   35.64  ? 279 ALA A C   1 
ATOM   2270 O  O   . ALA A 1 283 ? -19.106 -36.387 0.65    1   38.17  ? 279 ALA A O   1 
ATOM   2271 C  CB  . ALA A 1 283 ? -18.99  -34.182 -1.69   1   31.5   ? 279 ALA A CB  1 
ATOM   2272 N  N   . ALA A 1 284 ? -17.6   -34.836 1.253   1   31.1   ? 280 ALA A N   1 
ATOM   2273 C  CA  . ALA A 1 284 ? -16.826 -35.755 2.064   1   29.8   ? 280 ALA A CA  1 
ATOM   2274 C  C   . ALA A 1 284 ? -17.666 -36.38  3.178   1   30.94  ? 280 ALA A C   1 
ATOM   2275 O  O   . ALA A 1 284 ? -17.443 -37.549 3.493   1   32.03  ? 280 ALA A O   1 
ATOM   2276 C  CB  . ALA A 1 284 ? -15.618 -35.058 2.615   1   27.81  ? 280 ALA A CB  1 
ATOM   2277 N  N   . LEU A 1 285 ? -18.621 -35.612 3.756   1   29.68  ? 281 LEU A N   1 
ATOM   2278 C  CA  . LEU A 1 285 ? -19.482 -36.051 4.856   1   27.93  ? 281 LEU A CA  1 
ATOM   2279 C  C   . LEU A 1 285 ? -20.214 -37.351 4.5     1   31.95  ? 281 LEU A C   1 
ATOM   2280 O  O   . LEU A 1 285 ? -20.552 -38.123 5.41    1   32.35  ? 281 LEU A O   1 
ATOM   2281 C  CB  . LEU A 1 285 ? -20.494 -34.96  5.203   1   27.66  ? 281 LEU A CB  1 
ATOM   2282 C  CG  . LEU A 1 285 ? -19.924 -33.716 5.895   1   28.63  ? 281 LEU A CG  1 
ATOM   2283 C  CD1 . LEU A 1 285 ? -21.015 -32.685 6.135   1   26.21  ? 281 LEU A CD1 1 
ATOM   2284 C  CD2 . LEU A 1 285 ? -19.293 -34.101 7.219   1   28.04  ? 281 LEU A CD2 1 
ATOM   2285 N  N   . ALA A 1 286 ? -20.484 -37.569 3.189   1   28.68  ? 282 ALA A N   1 
ATOM   2286 C  CA  . ALA A 1 286 ? -21.251 -38.721 2.737   1   31.75  ? 282 ALA A CA  1 
ATOM   2287 C  C   . ALA A 1 286 ? -20.352 -39.882 2.32    1   30.54  ? 282 ALA A C   1 
ATOM   2288 O  O   . ALA A 1 286 ? -20.835 -40.854 1.742   1   31.18  ? 282 ALA A O   1 
ATOM   2289 C  CB  . ALA A 1 286 ? -22.154 -38.352 1.569   1   33.82  ? 282 ALA A CB  1 
ATOM   2290 N  N   . HIS A 1 287 ? -19.048 -39.75  2.56    1   29.49  ? 283 HIS A N   1 
ATOM   2291 C  CA  . HIS A 1 287 ? -18.124 -40.759 2.086   1   30.99  ? 283 HIS A CA  1 
ATOM   2292 C  C   . HIS A 1 287 ? -18.377 -42.036 2.88    1   31.54  ? 283 HIS A C   1 
ATOM   2293 O  O   . HIS A 1 287 ? -18.714 -41.963 4.059   1   32.03  ? 283 HIS A O   1 
ATOM   2294 C  CB  . HIS A 1 287 ? -16.677 -40.274 2.209   1   30.18  ? 283 HIS A CB  1 
ATOM   2295 C  CG  . HIS A 1 287 ? -15.738 -41.144 1.438   1   33.25  ? 283 HIS A CG  1 
ATOM   2296 N  ND1 . HIS A 1 287 ? -15.382 -42.409 1.863   1   32.13  ? 283 HIS A ND1 1 
ATOM   2297 C  CD2 . HIS A 1 287 ? -15.131 -40.958 0.241   1   31.26  ? 283 HIS A CD2 1 
ATOM   2298 C  CE1 . HIS A 1 287 ? -14.579 -42.946 0.946   1   33.54  ? 283 HIS A CE1 1 
ATOM   2299 N  NE2 . HIS A 1 287 ? -14.407 -42.083 -0.041  1   30.54  ? 283 HIS A NE2 1 
ATOM   2300 N  N   . PRO A 1 288 ? -18.254 -43.227 2.258   1   32.24  ? 284 PRO A N   1 
ATOM   2301 C  CA  . PRO A 1 288 ? -18.478 -44.492 2.963   1   33.26  ? 284 PRO A CA  1 
ATOM   2302 C  C   . PRO A 1 288 ? -17.592 -44.694 4.191   1   33.06  ? 284 PRO A C   1 
ATOM   2303 O  O   . PRO A 1 288 ? -17.997 -45.384 5.134   1   34.45  ? 284 PRO A O   1 
ATOM   2304 C  CB  . PRO A 1 288 ? -18.287 -45.595 1.91    1   34.35  ? 284 PRO A CB  1 
ATOM   2305 C  CG  . PRO A 1 288 ? -18.295 -44.862 0.574   1   34.78  ? 284 PRO A CG  1 
ATOM   2306 C  CD  . PRO A 1 288 ? -17.902 -43.421 0.837   1   33.59  ? 284 PRO A CD  1 
ATOM   2307 N  N   . PHE A 1 289 ? -16.405 -44.063 4.193   1   32.39  ? 285 PHE A N   1 
ATOM   2308 C  CA  . PHE A 1 289 ? -15.539 -44.039 5.365   1   32.65  ? 285 PHE A CA  1 
ATOM   2309 C  C   . PHE A 1 289 ? -16.31  -43.711 6.648   1   33.25  ? 285 PHE A C   1 
ATOM   2310 O  O   . PHE A 1 289 ? -15.996 -44.238 7.706   1   34.19  ? 285 PHE A O   1 
ATOM   2311 C  CB  . PHE A 1 289 ? -14.405 -43.031 5.202   1   31.8   ? 285 PHE A CB  1 
ATOM   2312 C  CG  . PHE A 1 289 ? -13.418 -43.038 6.356   1   34.55  ? 285 PHE A CG  1 
ATOM   2313 C  CD1 . PHE A 1 289 ? -12.584 -44.138 6.576   1   37.66  ? 285 PHE A CD1 1 
ATOM   2314 C  CD2 . PHE A 1 289 ? -13.287 -41.938 7.198   1   35.24  ? 285 PHE A CD2 1 
ATOM   2315 C  CE1 . PHE A 1 289 ? -11.665 -44.149 7.614   1   35.48  ? 285 PHE A CE1 1 
ATOM   2316 C  CE2 . PHE A 1 289 ? -12.328 -41.927 8.209   1   34.8   ? 285 PHE A CE2 1 
ATOM   2317 C  CZ  . PHE A 1 289 ? -11.537 -43.041 8.418   1   36.27  ? 285 PHE A CZ  1 
ATOM   2318 N  N   . PHE A 1 290 ? -17.331 -42.857 6.574   1   31.94  ? 286 PHE A N   1 
ATOM   2319 C  CA  . PHE A 1 290 ? -17.979 -42.441 7.805   1   33.99  ? 286 PHE A CA  1 
ATOM   2320 C  C   . PHE A 1 290 ? -19.223 -43.275 8.127   1   38.35  ? 286 PHE A C   1 
ATOM   2321 O  O   . PHE A 1 290 ? -19.933 -42.921 9.064   1   38.99  ? 286 PHE A O   1 
ATOM   2322 C  CB  . PHE A 1 290 ? -18.335 -40.954 7.771   1   30.11  ? 286 PHE A CB  1 
ATOM   2323 C  CG  . PHE A 1 290 ? -17.161 -40.003 7.571   1   28.58  ? 286 PHE A CG  1 
ATOM   2324 C  CD1 . PHE A 1 290 ? -16.18  -39.877 8.542   1   29.17  ? 286 PHE A CD1 1 
ATOM   2325 C  CD2 . PHE A 1 290 ? -17.04  -39.224 6.424   1   27.07  ? 286 PHE A CD2 1 
ATOM   2326 C  CE1 . PHE A 1 290 ? -15.123 -38.986 8.371   1   28.61  ? 286 PHE A CE1 1 
ATOM   2327 C  CE2 . PHE A 1 290 ? -15.972 -38.358 6.255   1   25.29  ? 286 PHE A CE2 1 
ATOM   2328 C  CZ  . PHE A 1 290 ? -15.027 -38.22  7.234   1   26.31  ? 286 PHE A CZ  1 
ATOM   2329 N  N   . GLN A 1 291 ? -19.463 -44.39  7.413   1   42.17  ? 287 GLN A N   1 
ATOM   2330 C  CA  . GLN A 1 291 ? -20.714 -45.125 7.555   1   45.94  ? 287 GLN A CA  1 
ATOM   2331 C  C   . GLN A 1 291 ? -20.992 -45.477 9.023   1   50.81  ? 287 GLN A C   1 
ATOM   2332 O  O   . GLN A 1 291 ? -22.14  -45.453 9.473   1   54.71  ? 287 GLN A O   1 
ATOM   2333 C  CB  . GLN A 1 291 ? -20.843 -46.291 6.571   1   51     ? 287 GLN A CB  1 
ATOM   2334 C  CG  . GLN A 1 291 ? -19.971 -47.506 6.889   1   67.84  ? 287 GLN A CG  1 
ATOM   2335 C  CD  . GLN A 1 291 ? -20.031 -48.641 5.875   1   72.43  ? 287 GLN A CD  1 
ATOM   2336 O  OE1 . GLN A 1 291 ? -20.873 -49.546 5.957   1   73.11  ? 287 GLN A OE1 1 
ATOM   2337 N  NE2 . GLN A 1 291 ? -19.09  -48.638 4.938   1   67.88  ? 287 GLN A NE2 1 
ATOM   2338 N  N   . ASP A 1 292 ? -19.95  -45.777 9.801   1   50.68  ? 288 ASP A N   1 
ATOM   2339 C  CA  . ASP A 1 292 ? -20.192 -46.268 11.149  1   51.82  ? 288 ASP A CA  1 
ATOM   2340 C  C   . ASP A 1 292 ? -19.816 -45.219 12.197  1   46.97  ? 288 ASP A C   1 
ATOM   2341 O  O   . ASP A 1 292 ? -19.602 -45.558 13.35   1   46.7   ? 288 ASP A O   1 
ATOM   2342 C  CB  . ASP A 1 292 ? -19.508 -47.616 11.348  1   59.49  ? 288 ASP A CB  1 
ATOM   2343 C  CG  . ASP A 1 292 ? -18.041 -47.687 10.923  1   68.19  ? 288 ASP A CG  1 
ATOM   2344 O  OD1 . ASP A 1 292 ? -17.524 -46.692 10.323  1   62.27  ? 288 ASP A OD1 1 
ATOM   2345 O  OD2 . ASP A 1 292 ? -17.416 -48.748 11.19   1   74.03  ? 288 ASP A OD2 1 
ATOM   2346 N  N   . VAL A 1 293 ? -19.744 -43.936 11.82   1   43.75  ? 289 VAL A N   1 
ATOM   2347 C  CA  . VAL A 1 293 ? -19.121 -42.959 12.707  1   40.7   ? 289 VAL A CA  1 
ATOM   2348 C  C   . VAL A 1 293 ? -19.911 -42.807 14.015  1   44.93  ? 289 VAL A C   1 
ATOM   2349 O  O   . VAL A 1 293 ? -21.144 -42.944 14.04   1   44.43  ? 289 VAL A O   1 
ATOM   2350 C  CB  . VAL A 1 293 ? -18.885 -41.614 12.002  1   36.5   ? 289 VAL A CB  1 
ATOM   2351 C  CG1 . VAL A 1 293 ? -20.194 -40.993 11.533  1   36.16  ? 289 VAL A CG1 1 
ATOM   2352 C  CG2 . VAL A 1 293 ? -18.08  -40.644 12.857  1   33.7   ? 289 VAL A CG2 1 
ATOM   2353 N  N   . THR A 1 294 ? -19.173 -42.56  15.109  1   45.21  ? 290 THR A N   1 
ATOM   2354 C  CA  . THR A 1 294 ? -19.769 -42.113 16.359  1   46.29  ? 290 THR A CA  1 
ATOM   2355 C  C   . THR A 1 294 ? -18.9   -40.98  16.875  1   45.97  ? 290 THR A C   1 
ATOM   2356 O  O   . THR A 1 294 ? -17.931 -40.63  16.204  1   47.98  ? 290 THR A O   1 
ATOM   2357 C  CB  . THR A 1 294 ? -19.976 -43.217 17.404  1   48.87  ? 290 THR A CB  1 
ATOM   2358 O  OG1 . THR A 1 294 ? -18.788 -43.994 17.504  1   48     ? 290 THR A OG1 1 
ATOM   2359 C  CG2 . THR A 1 294 ? -21.184 -44.097 17.125  1   48.96  ? 290 THR A CG2 1 
ATOM   2360 N  N   . LYS A 1 295 ? -19.264 -40.421 18.038  1   43.57  ? 291 LYS A N   1 
ATOM   2361 C  CA  . LYS A 1 295 ? -18.471 -39.366 18.647  1   44.29  ? 291 LYS A CA  1 
ATOM   2362 C  C   . LYS A 1 295 ? -18.079 -39.775 20.064  1   45.44  ? 291 LYS A C   1 
ATOM   2363 O  O   . LYS A 1 295 ? -18.707 -39.344 21.038  1   46.91  ? 291 LYS A O   1 
ATOM   2364 C  CB  . LYS A 1 295 ? -19.18  -38.01  18.67   1   46.85  ? 291 LYS A CB  1 
ATOM   2365 C  CG  . LYS A 1 295 ? -19.985 -37.709 17.406  1   55.67  ? 291 LYS A CG  1 
ATOM   2366 C  CD  . LYS A 1 295 ? -19.345 -37.145 16.146  1   45.56  ? 291 LYS A CD  1 
ATOM   2367 C  CE  . LYS A 1 295 ? -20.322 -36.039 15.801  1   47.67  ? 291 LYS A CE  1 
ATOM   2368 N  NZ  . LYS A 1 295 ? -20.749 -35.124 16.878  1   39.67  ? 291 LYS A NZ  1 
ATOM   2369 N  N   . PRO A 1 296 ? -17.051 -40.644 20.218  1   41.88  ? 292 PRO A N   1 
ATOM   2370 C  CA  . PRO A 1 296 ? -16.626 -41.007 21.565  1   40.72  ? 292 PRO A CA  1 
ATOM   2371 C  C   . PRO A 1 296 ? -15.737 -39.912 22.164  1   40.16  ? 292 PRO A C   1 
ATOM   2372 O  O   . PRO A 1 296 ? -15.129 -39.108 21.443  1   38.96  ? 292 PRO A O   1 
ATOM   2373 C  CB  . PRO A 1 296 ? -15.901 -42.335 21.258  1   38.83  ? 292 PRO A CB  1 
ATOM   2374 C  CG  . PRO A 1 296 ? -15.212 -42.071 19.932  1   37.26  ? 292 PRO A CG  1 
ATOM   2375 C  CD  . PRO A 1 296 ? -16.29  -41.337 19.149  1   36.51  ? 292 PRO A CD  1 
ATOM   2376 N  N   . VAL A 1 297 ? -15.696 -39.889 23.499  1   38.07  ? 293 VAL A N   1 
ATOM   2377 C  CA  . VAL A 1 297 ? -14.788 -39.039 24.258  1   38.07  ? 293 VAL A CA  1 
ATOM   2378 C  C   . VAL A 1 297 ? -13.349 -39.48  23.984  1   40.4   ? 293 VAL A C   1 
ATOM   2379 O  O   . VAL A 1 297 ? -13.108 -40.621 23.571  1   39.22  ? 293 VAL A O   1 
ATOM   2380 C  CB  . VAL A 1 297 ? -15.115 -39.094 25.766  1   39.15  ? 293 VAL A CB  1 
ATOM   2381 C  CG1 . VAL A 1 297 ? -16.547 -38.634 26.055  1   43.84  ? 293 VAL A CG1 1 
ATOM   2382 C  CG2 . VAL A 1 297 ? -14.87  -40.47  26.365  1   38.77  ? 293 VAL A CG2 1 
ATOM   2383 N  N   . PRO A 1 298 ? -12.356 -38.58  24.143  1   39.8   ? 294 PRO A N   1 
ATOM   2384 C  CA  . PRO A 1 298 ? -10.956 -38.986 24.037  1   38.92  ? 294 PRO A CA  1 
ATOM   2385 C  C   . PRO A 1 298 ? -10.652 -40.134 25.017  1   41.3   ? 294 PRO A C   1 
ATOM   2386 O  O   . PRO A 1 298 ? -11.162 -40.164 26.141  1   43.28  ? 294 PRO A O   1 
ATOM   2387 C  CB  . PRO A 1 298 ? -10.232 -37.664 24.354  1   37.52  ? 294 PRO A CB  1 
ATOM   2388 C  CG  . PRO A 1 298 ? -11.19  -36.578 24.005  1   38.37  ? 294 PRO A CG  1 
ATOM   2389 C  CD  . PRO A 1 298 ? -12.537 -37.141 24.402  1   41.22  ? 294 PRO A CD  1 
ATOM   2390 N  N   . HIS A 1 299 ? -9.822  -41.096 24.584  1   41.95  ? 295 HIS A N   1 
ATOM   2391 C  CA  . HIS A 1 299 ? -9.435  -42.265 25.37   1   44.34  ? 295 HIS A CA  1 
ATOM   2392 C  C   . HIS A 1 299 ? -8.386  -41.913 26.435  1   47.56  ? 295 HIS A C   1 
ATOM   2393 O  O   . HIS A 1 299 ? -8.046  -42.733 27.28   1   51.36  ? 295 HIS A O   1 
ATOM   2394 C  CB  . HIS A 1 299 ? -8.903  -43.346 24.425  1   43.79  ? 295 HIS A CB  1 
ATOM   2395 C  CG  . HIS A 1 299 ? -7.689  -42.918 23.675  1   43.37  ? 295 HIS A CG  1 
ATOM   2396 N  ND1 . HIS A 1 299 ? -6.546  -43.696 23.662  1   46.42  ? 295 HIS A ND1 1 
ATOM   2397 C  CD2 . HIS A 1 299 ? -7.408  -41.808 22.973  1   41.17  ? 295 HIS A CD2 1 
ATOM   2398 C  CE1 . HIS A 1 299 ? -5.61   -43.081 22.954  1   46.57  ? 295 HIS A CE1 1 
ATOM   2399 N  NE2 . HIS A 1 299 ? -6.12   -41.929 22.523  1   44.64  ? 295 HIS A NE2 1 
ATOM   2400 N  N   . LEU A 1 300 ? -7.877  -40.675 26.419  1   50.41  ? 296 LEU A N   1 
ATOM   2401 C  CA  . LEU A 1 300 ? -6.851  -40.224 27.351  1   49.81  ? 296 LEU A CA  1 
ATOM   2402 C  C   . LEU A 1 300 ? -7.376  -38.972 28.042  1   51.32  ? 296 LEU A C   1 
ATOM   2403 O  O   . LEU A 1 300 ? -8.236  -38.308 27.466  1   53.85  ? 296 LEU A O   1 
ATOM   2404 C  CB  . LEU A 1 300 ? -5.59   -39.962 26.523  1   46.83  ? 296 LEU A CB  1 
ATOM   2405 C  CG  . LEU A 1 300 ? -4.817  -41.205 26.049  1   45.49  ? 296 LEU A CG  1 
ATOM   2406 C  CD1 . LEU A 1 300 ? -3.773  -40.73  25.058  1   45.73  ? 296 LEU A CD1 1 
ATOM   2407 C  CD2 . LEU A 1 300 ? -4.144  -42.05  27.155  1   45.71  ? 296 LEU A CD2 1 
ATOM   2408 N  N   . ARG A 1 301 ? -6.914  -38.701 29.275  1   53.4   ? 297 ARG A N   1 
ATOM   2409 C  CA  . ARG A 1 301 ? -7.296  -37.51  30.04   1   55.84  ? 297 ARG A CA  1 
ATOM   2410 C  C   . ARG A 1 301 ? -6.967  -36.205 29.285  1   55.44  ? 297 ARG A C   1 
ATOM   2411 O  O   . ARG A 1 301 ? -5.9    -36.186 28.617  1   56.39  ? 297 ARG A O   1 
ATOM   2412 C  CB  . ARG A 1 301 ? -6.667  -37.487 31.438  1   58.79  ? 297 ARG A CB  1 
ATOM   2413 C  CG  . ARG A 1 301 ? -7.563  -38.263 32.391  1   68.45  ? 297 ARG A CG  1 
ATOM   2414 C  CD  . ARG A 1 301 ? -7.326  -38.035 33.871  1   80.31  ? 297 ARG A CD  1 
ATOM   2415 N  NE  . ARG A 1 301 ? -8.366  -38.741 34.632  1   91.23  ? 297 ARG A NE  1 
ATOM   2416 C  CZ  . ARG A 1 301 ? -8.192  -39.687 35.559  1   93.61  ? 297 ARG A CZ  1 
ATOM   2417 N  NH1 . ARG A 1 301 ? -9.255  -40.273 36.096  1   87.4   ? 297 ARG A NH1 1 
ATOM   2418 N  NH2 . ARG A 1 301 ? -6.968  -40.059 35.92   1   92.17  ? 297 ARG A NH2 1 
ATOM   2419 N  N   . GLY B 2 1   ? -15.405 -24.276 -12.161 1   34.42  ? 171 GLY B N   1 
ATOM   2420 C  CA  . GLY B 2 1   ? -14.651 -25.07  -11.178 1   35.2   ? 171 GLY B CA  1 
ATOM   2421 C  C   . GLY B 2 1   ? -14.681 -24.446 -9.773  1   35.82  ? 171 GLY B C   1 
ATOM   2422 O  O   . GLY B 2 1   ? -15.527 -23.599 -9.455  1   33.38  ? 171 GLY B O   1 
ATOM   2423 N  N   . VAL B 2 2   ? -13.706 -24.85  -8.941  1   36.89  ? 172 VAL B N   1 
ATOM   2424 C  CA  . VAL B 2 2   ? -13.743 -24.616 -7.514  1   38.01  ? 172 VAL B CA  1 
ATOM   2425 C  C   . VAL B 2 2   ? -13.72  -23.112 -7.239  1   39.57  ? 172 VAL B C   1 
ATOM   2426 O  O   . VAL B 2 2   ? -14.198 -22.696 -6.197  1   40.43  ? 172 VAL B O   1 
ATOM   2427 C  CB  . VAL B 2 2   ? -12.65  -25.405 -6.758  1   38.88  ? 172 VAL B CB  1 
ATOM   2428 C  CG1 . VAL B 2 2   ? -11.258 -24.84  -6.999  1   37.14  ? 172 VAL B CG1 1 
ATOM   2429 C  CG2 . VAL B 2 2   ? -12.922 -25.501 -5.254  1   37.94  ? 172 VAL B CG2 1 
ATOM   2430 N  N   . ASN B 2 3   ? -13.218 -22.292 -8.18   1   41.31  ? 173 ASN B N   1 
ATOM   2431 C  CA  . ASN B 2 3   ? -13.084 -20.85  -7.961  1   38.78  ? 173 ASN B CA  1 
ATOM   2432 C  C   . ASN B 2 3   ? -14.453 -20.19  -7.898  1   37.5   ? 173 ASN B C   1 
ATOM   2433 O  O   . ASN B 2 3   ? -14.575 -19.071 -7.392  1   34.23  ? 173 ASN B O   1 
ATOM   2434 C  CB  . ASN B 2 3   ? -12.212 -20.163 -9.015  1   38.01  ? 173 ASN B CB  1 
ATOM   2435 C  CG  . ASN B 2 3   ? -10.763 -20.598 -8.939  1   42.3   ? 173 ASN B CG  1 
ATOM   2436 O  OD1 . ASN B 2 3   ? -10.293 -21.113 -7.911  1   42.51  ? 173 ASN B OD1 1 
ATOM   2437 N  ND2 . ASN B 2 3   ? -10.014 -20.379 -10.007 1   42.44  ? 173 ASN B ND2 1 
ATOM   2438 N  N   . GLU B 2 4   ? -15.449 -20.875 -8.488  1   41.71  ? 174 GLU B N   1 
ATOM   2439 C  CA  . GLU B 2 4   ? -16.846 -20.448 -8.509  1   41.47  ? 174 GLU B CA  1 
ATOM   2440 C  C   . GLU B 2 4   ? -17.67  -21.337 -7.573  1   39.11  ? 174 GLU B C   1 
ATOM   2441 O  O   . GLU B 2 4   ? -18.89  -21.34  -7.671  1   37.46  ? 174 GLU B O   1 
ATOM   2442 C  CB  . GLU B 2 4   ? -17.473 -20.523 -9.906  1   42.01  ? 174 GLU B CB  1 
ATOM   2443 C  CG  . GLU B 2 4   ? -16.479 -20.409 -11.059 1   48.84  ? 174 GLU B CG  1 
ATOM   2444 C  CD  . GLU B 2 4   ? -17.068 -20.314 -12.465 1   59.45  ? 174 GLU B CD  1 
ATOM   2445 O  OE1 . GLU B 2 4   ? -18.043 -21.034 -12.834 1   59.15  ? 174 GLU B OE1 1 
ATOM   2446 O  OE2 . GLU B 2 4   ? -16.508 -19.485 -13.219 1   60.19  ? 174 GLU B OE2 1 
ATOM   2447 N  N   . VAL B 2 5   ? -16.981 -22.1   -6.7    1   37.92  ? 175 VAL B N   1 
ATOM   2448 C  CA  . VAL B 2 5   ? -17.53  -22.907 -5.611  1   37.73  ? 175 VAL B CA  1 
ATOM   2449 C  C   . VAL B 2 5   ? -18.884 -23.525 -5.986  1   38.61  ? 175 VAL B C   1 
ATOM   2450 O  O   . VAL B 2 5   ? -19.89  -23.262 -5.321  1   40.07  ? 175 VAL B O   1 
ATOM   2451 C  CB  . VAL B 2 5   ? -17.613 -22.197 -4.238  1   34.4   ? 175 VAL B CB  1 
ATOM   2452 C  CG1 . VAL B 2 5   ? -16.246 -21.965 -3.621  1   33.65  ? 175 VAL B CG1 1 
ATOM   2453 C  CG2 . VAL B 2 5   ? -18.401 -20.895 -4.276  1   32.34  ? 175 VAL B CG2 1 
ATOM   2454 N  N   . PRO B 2 6   ? -18.964 -24.41  -7.003  1   37.58  ? 176 PRO B N   1 
ATOM   2455 C  CA  . PRO B 2 6   ? -20.202 -25.145 -7.273  1   37.44  ? 176 PRO B CA  1 
ATOM   2456 C  C   . PRO B 2 6   ? -20.901 -25.733 -6.039  1   40.89  ? 176 PRO B C   1 
ATOM   2457 O  O   . PRO B 2 6   ? -22.125 -25.746 -6.016  1   49.24  ? 176 PRO B O   1 
ATOM   2458 C  CB  . PRO B 2 6   ? -19.774 -26.254 -8.283  1   36.54  ? 176 PRO B CB  1 
ATOM   2459 C  CG  . PRO B 2 6   ? -18.241 -26.302 -8.224  1   34.27  ? 176 PRO B CG  1 
ATOM   2460 C  CD  . PRO B 2 6   ? -17.85  -24.868 -7.854  1   36.84  ? 176 PRO B CD  1 
ATOM   2461 N  N   . ASP B 2 7   ? -20.161 -26.231 -5.027  1   38     ? 177 ASP B N   1 
ATOM   2462 C  CA  . ASP B 2 7   ? -20.809 -26.933 -3.92   1   38.27  ? 177 ASP B CA  1 
ATOM   2463 C  C   . ASP B 2 7   ? -21.401 -25.969 -2.888  1   36.55  ? 177 ASP B C   1 
ATOM   2464 O  O   . ASP B 2 7   ? -22.144 -26.43  -2.02   1   36.82  ? 177 ASP B O   1 
ATOM   2465 C  CB  . ASP B 2 7   ? -19.993 -28.064 -3.295  1   37.9   ? 177 ASP B CB  1 
ATOM   2466 C  CG  . ASP B 2 7   ? -19.939 -29.305 -4.163  1   43.29  ? 177 ASP B CG  1 
ATOM   2467 O  OD1 . ASP B 2 7   ? -20.341 -29.177 -5.339  1   48.88  ? 177 ASP B OD1 1 
ATOM   2468 O  OD2 . ASP B 2 7   ? -19.53  -30.381 -3.674  1   44.11  ? 177 ASP B OD2 1 
ATOM   2469 N  N   . TYR B 2 8   ? -21.095 -24.662 -3.002  1   32.43  ? 178 TYR B N   1 
ATOM   2470 C  CA  . TYR B 2 8   ? -21.447 -23.71  -1.959  1   30.8   ? 178 TYR B CA  1 
ATOM   2471 C  C   . TYR B 2 8   ? -22.104 -22.45  -2.52   1   33.33  ? 178 TYR B C   1 
ATOM   2472 O  O   . TYR B 2 8   ? -22.606 -21.636 -1.74   1   34.6   ? 178 TYR B O   1 
ATOM   2473 C  CB  . TYR B 2 8   ? -20.294 -23.329 -1.019  1   29.66  ? 178 TYR B CB  1 
ATOM   2474 C  CG  . TYR B 2 8   ? -19.602 -24.512 -0.354  1   27.92  ? 178 TYR B CG  1 
ATOM   2475 C  CD1 . TYR B 2 8   ? -20.158 -25.094 0.771   1   27.16  ? 178 TYR B CD1 1 
ATOM   2476 C  CD2 . TYR B 2 8   ? -18.432 -25.054 -0.867  1   25.96  ? 178 TYR B CD2 1 
ATOM   2477 C  CE1 . TYR B 2 8   ? -19.552 -26.163 1.392   1   27.94  ? 178 TYR B CE1 1 
ATOM   2478 C  CE2 . TYR B 2 8   ? -17.84  -26.156 -0.279  1   26.57  ? 178 TYR B CE2 1 
ATOM   2479 C  CZ  . TYR B 2 8   ? -18.397 -26.708 0.859   1   28.6   ? 178 TYR B CZ  1 
ATOM   2480 O  OH  . TYR B 2 8   ? -17.848 -27.817 1.477   1   32.14  ? 178 TYR B OH  1 
ATOM   2481 N  N   . HIS B 2 9   ? -22.163 -22.285 -3.852  1   37.5   ? 179 HIS B N   1 
ATOM   2482 C  CA  . HIS B 2 9   ? -22.673 -21.014 -4.356  1   40.79  ? 179 HIS B CA  1 
ATOM   2483 C  C   . HIS B 2 9   ? -24.122 -20.783 -3.907  1   39.35  ? 179 HIS B C   1 
ATOM   2484 O  O   . HIS B 2 9   ? -24.485 -19.672 -3.501  1   34.76  ? 179 HIS B O   1 
ATOM   2485 C  CB  . HIS B 2 9   ? -22.328 -20.793 -5.834  1   52.26  ? 179 HIS B CB  1 
ATOM   2486 C  CG  . HIS B 2 9   ? -23.339 -21.352 -6.763  1   70.71  ? 179 HIS B CG  1 
ATOM   2487 N  ND1 . HIS B 2 9   ? -24.115 -20.549 -7.572  1   76.97  ? 179 HIS B ND1 1 
ATOM   2488 C  CD2 . HIS B 2 9   ? -23.711 -22.632 -7.005  1   75.62  ? 179 HIS B CD2 1 
ATOM   2489 C  CE1 . HIS B 2 9   ? -24.939 -21.337 -8.26   1   90.28  ? 179 HIS B CE1 1 
ATOM   2490 N  NE2 . HIS B 2 9   ? -24.711 -22.603 -7.933  1   78.7   ? 179 HIS B NE2 1 
ATOM   2491 N  N   . GLU B 2 10  ? -24.939 -21.847 -3.936  1   37.8   ? 180 GLU B N   1 
ATOM   2492 C  CA  . GLU B 2 10  ? -26.337 -21.692 -3.599  1   36.83  ? 180 GLU B CA  1 
ATOM   2493 C  C   . GLU B 2 10  ? -26.432 -21.312 -2.124  1   34.84  ? 180 GLU B C   1 
ATOM   2494 O  O   . GLU B 2 10  ? -27.101 -20.33  -1.8    1   33.49  ? 180 GLU B O   1 
ATOM   2495 C  CB  . GLU B 2 10  ? -27.16  -22.885 -4.08   1   42.68  ? 180 GLU B CB  1 
ATOM   2496 C  CG  . GLU B 2 10  ? -28.667 -22.726 -3.872  1   49.05  ? 180 GLU B CG  1 
ATOM   2497 C  CD  . GLU B 2 10  ? -29.541 -23.964 -4.094  1   55.48  ? 180 GLU B CD  1 
ATOM   2498 O  OE1 . GLU B 2 10  ? -29.019 -25.093 -4.205  1   62.96  ? 180 GLU B OE1 1 
ATOM   2499 O  OE2 . GLU B 2 10  ? -30.778 -23.82  -4.148  1   57.42  ? 180 GLU B OE2 1 
ATOM   2500 N  N   . ASP B 2 11  ? -25.728 -22.054 -1.253  1   33.08  ? 181 ASP B N   1 
ATOM   2501 C  CA  . ASP B 2 11  ? -25.771 -21.756 0.175   1   32.35  ? 181 ASP B CA  1 
ATOM   2502 C  C   . ASP B 2 11  ? -25.284 -20.324 0.382   1   33.18  ? 181 ASP B C   1 
ATOM   2503 O  O   . ASP B 2 11  ? -25.823 -19.598 1.212   1   36.39  ? 181 ASP B O   1 
ATOM   2504 C  CB  . ASP B 2 11  ? -24.962 -22.708 1.056   1   30.69  ? 181 ASP B CB  1 
ATOM   2505 C  CG  . ASP B 2 11  ? -25.442 -24.153 1.191   1   32.61  ? 181 ASP B CG  1 
ATOM   2506 O  OD1 . ASP B 2 11  ? -26.634 -24.399 0.876   1   32.36  ? 181 ASP B OD1 1 
ATOM   2507 O  OD2 . ASP B 2 11  ? -24.619 -25.044 1.603   1   32.82  ? 181 ASP B OD2 1 
ATOM   2508 N  N   . ILE B 2 12  ? -24.246 -19.919 -0.358  1   32.03  ? 182 ILE B N   1 
ATOM   2509 C  CA  . ILE B 2 12  ? -23.653 -18.611 -0.131  1   32.36  ? 182 ILE B CA  1 
ATOM   2510 C  C   . ILE B 2 12  ? -24.657 -17.506 -0.461  1   34.99  ? 182 ILE B C   1 
ATOM   2511 O  O   . ILE B 2 12  ? -24.743 -16.498 0.25    1   38.01  ? 182 ILE B O   1 
ATOM   2512 C  CB  . ILE B 2 12  ? -22.302 -18.464 -0.852  1   30.08  ? 182 ILE B CB  1 
ATOM   2513 C  CG1 . ILE B 2 12  ? -21.233 -19.315 -0.147  1   30.09  ? 182 ILE B CG1 1 
ATOM   2514 C  CG2 . ILE B 2 12  ? -21.882 -17     -0.864  1   28.42  ? 182 ILE B CG2 1 
ATOM   2515 C  CD1 . ILE B 2 12  ? -20.03  -19.648 -1.018  1   29.04  ? 182 ILE B CD1 1 
ATOM   2516 N  N   . HIS B 2 13  ? -25.439 -17.72  -1.527  1   34.53  ? 183 HIS B N   1 
ATOM   2517 C  CA  . HIS B 2 13  ? -26.375 -16.723 -2.017  1   31.27  ? 183 HIS B CA  1 
ATOM   2518 C  C   . HIS B 2 13  ? -27.541 -16.597 -1.022  1   35.77  ? 183 HIS B C   1 
ATOM   2519 O  O   . HIS B 2 13  ? -27.91  -15.482 -0.628  1   35.78  ? 183 HIS B O   1 
ATOM   2520 C  CB  . HIS B 2 13  ? -26.748 -17.062 -3.457  1   27.58  ? 183 HIS B CB  1 
ATOM   2521 C  CG  . HIS B 2 13  ? -27.931 -16.311 -3.922  1   26.96  ? 183 HIS B CG  1 
ATOM   2522 N  ND1 . HIS B 2 13  ? -27.748 -15.062 -4.455  1   27.61  ? 183 HIS B ND1 1 
ATOM   2523 C  CD2 . HIS B 2 13  ? -29.244 -16.523 -3.95   1   27.88  ? 183 HIS B CD2 1 
ATOM   2524 C  CE1 . HIS B 2 13  ? -28.918 -14.523 -4.788  1   28.26  ? 183 HIS B CE1 1 
ATOM   2525 N  NE2 . HIS B 2 13  ? -29.838 -15.398 -4.498  1   29.57  ? 183 HIS B NE2 1 
ATOM   2526 N  N   . THR B 2 14  ? -28.063 -17.722 -0.559  1   34.29  ? 184 THR B N   1 
ATOM   2527 C  CA  . THR B 2 14  ? -29.132 -17.687 0.452   1   34.99  ? 184 THR B CA  1 
ATOM   2528 C  C   . THR B 2 14  ? -28.649 -16.908 1.654   1   36.35  ? 184 THR B C   1 
ATOM   2529 O  O   . THR B 2 14  ? -29.412 -16.069 2.154   1   40.03  ? 184 THR B O   1 
ATOM   2530 C  CB  . THR B 2 14  ? -29.53  -19.119 0.804   1   36.98  ? 184 THR B CB  1 
ATOM   2531 O  OG1 . THR B 2 14  ? -30.118 -19.661 -0.372  1   37.93  ? 184 THR B OG1 1 
ATOM   2532 C  CG2 . THR B 2 14  ? -30.519 -19.186 1.952   1   37.87  ? 184 THR B CG2 1 
ATOM   2533 N  N   . TYR B 2 15  ? -27.407 -17.127 2.069   1   33.1   ? 185 TYR B N   1 
ATOM   2534 C  CA  . TYR B 2 15  ? -26.872 -16.481 3.294   1   33     ? 185 TYR B CA  1 
ATOM   2535 C  C   . TYR B 2 15  ? -26.746 -14.968 3.124   1   32.55  ? 185 TYR B C   1 
ATOM   2536 O  O   . TYR B 2 15  ? -27.074 -14.231 4.06    1   32.87  ? 185 TYR B O   1 
ATOM   2537 C  CB  . TYR B 2 15  ? -25.543 -17.149 3.651   1   33.16  ? 185 TYR B CB  1 
ATOM   2538 C  CG  . TYR B 2 15  ? -24.96  -16.588 4.935   1   34.59  ? 185 TYR B CG  1 
ATOM   2539 C  CD1 . TYR B 2 15  ? -25.688 -16.64  6.113   1   36.55  ? 185 TYR B CD1 1 
ATOM   2540 C  CD2 . TYR B 2 15  ? -23.718 -15.973 4.954   1   32.83  ? 185 TYR B CD2 1 
ATOM   2541 C  CE1 . TYR B 2 15  ? -25.187 -16.117 7.288   1   37.15  ? 185 TYR B CE1 1 
ATOM   2542 C  CE2 . TYR B 2 15  ? -23.205 -15.446 6.125   1   36.51  ? 185 TYR B CE2 1 
ATOM   2543 C  CZ  . TYR B 2 15  ? -23.943 -15.522 7.291   1   38.35  ? 185 TYR B CZ  1 
ATOM   2544 O  OH  . TYR B 2 15  ? -23.47  -15.016 8.456   1   42.72  ? 185 TYR B OH  1 
ATOM   2545 N  N   . LEU B 2 16  ? -26.286 -14.523 1.962   1   31.16  ? 186 LEU B N   1 
ATOM   2546 C  CA  . LEU B 2 16  ? -26.087 -13.075 1.717   1   31.88  ? 186 LEU B CA  1 
ATOM   2547 C  C   . LEU B 2 16  ? -27.451 -12.379 1.59    1   35.38  ? 186 LEU B C   1 
ATOM   2548 O  O   . LEU B 2 16  ? -27.543 -11.213 1.977   1   36.03  ? 186 LEU B O   1 
ATOM   2549 C  CB  . LEU B 2 16  ? -25.22  -12.896 0.474   1   31.85  ? 186 LEU B CB  1 
ATOM   2550 C  CG  . LEU B 2 16  ? -23.792 -13.437 0.544   1   30.53  ? 186 LEU B CG  1 
ATOM   2551 C  CD1 . LEU B 2 16  ? -23.189 -13.369 -0.842  1   28.83  ? 186 LEU B CD1 1 
ATOM   2552 C  CD2 . LEU B 2 16  ? -22.951 -12.667 1.539   1   28.86  ? 186 LEU B CD2 1 
ATOM   2553 N  N   . ARG B 2 17  ? -28.468 -13.094 1.11    1   37.62  ? 187 ARG B N   1 
ATOM   2554 C  CA  . ARG B 2 17  ? -29.835 -12.535 0.968   1   36.86  ? 187 ARG B CA  1 
ATOM   2555 C  C   . ARG B 2 17  ? -30.432 -12.293 2.363   1   40.9   ? 187 ARG B C   1 
ATOM   2556 O  O   . ARG B 2 17  ? -31.211 -11.348 2.519   1   42.08  ? 187 ARG B O   1 
ATOM   2557 C  CB  . ARG B 2 17  ? -30.685 -13.476 0.112   1   33.09  ? 187 ARG B CB  1 
ATOM   2558 C  CG  . ARG B 2 17  ? -30.382 -13.482 -1.376  1   32.3   ? 187 ARG B CG  1 
ATOM   2559 C  CD  . ARG B 2 17  ? -30.969 -12.266 -2.055  1   33.58  ? 187 ARG B CD  1 
ATOM   2560 N  NE  . ARG B 2 17  ? -32.415 -12.138 -1.856  1   30.79  ? 187 ARG B NE  1 
ATOM   2561 C  CZ  . ARG B 2 17  ? -33.329 -12.713 -2.617  1   31.71  ? 187 ARG B CZ  1 
ATOM   2562 N  NH1 . ARG B 2 17  ? -32.992 -13.228 -3.782  1   34.08  ? 187 ARG B NH1 1 
ATOM   2563 N  NH2 . ARG B 2 17  ? -34.581 -12.768 -2.213  1   27.91  ? 187 ARG B NH2 1 
ATOM   2564 N  N   . GLU B 2 18  ? -30.041 -13.103 3.341   1   42.67  ? 188 GLU B N   1 
ATOM   2565 C  CA  . GLU B 2 18  ? -30.527 -12.915 4.727   1   46.89  ? 188 GLU B CA  1 
ATOM   2566 C  C   . GLU B 2 18  ? -29.676 -11.854 5.432   1   42.51  ? 188 GLU B C   1 
ATOM   2567 O  O   . GLU B 2 18  ? -30.225 -11.098 6.236   1   43.62  ? 188 GLU B O   1 
ATOM   2568 C  CB  . GLU B 2 18  ? -30.525 -14.28  5.412   1   50.47  ? 188 GLU B CB  1 
ATOM   2569 C  CG  . GLU B 2 18  ? -29.977 -14.273 6.833   1   67.31  ? 188 GLU B CG  1 
ATOM   2570 C  CD  . GLU B 2 18  ? -29.729 -15.683 7.327   1   89.35  ? 188 GLU B CD  1 
ATOM   2571 O  OE1 . GLU B 2 18  ? -29.606 -16.586 6.474   1   107.39 ? 188 GLU B OE1 1 
ATOM   2572 O  OE2 . GLU B 2 18  ? -29.667 -15.88  8.556   1   101.9  ? 188 GLU B OE2 1 
ATOM   2573 N  N   . MET B 2 19  ? -28.399 -11.776 5.096   1   38.69  ? 189 MET B N   1 
ATOM   2574 C  CA  . MET B 2 19  ? -27.495 -10.844 5.805   1   37.87  ? 189 MET B CA  1 
ATOM   2575 C  C   . MET B 2 19  ? -27.692 -9.425  5.269   1   37.75  ? 189 MET B C   1 
ATOM   2576 O  O   . MET B 2 19  ? -27.406 -8.481  6.004   1   40.74  ? 189 MET B O   1 
ATOM   2577 C  CB  . MET B 2 19  ? -26.045 -11.301 5.634   1   38.53  ? 189 MET B CB  1 
ATOM   2578 C  CG  . MET B 2 19  ? -25.662 -12.518 6.441   1   44.15  ? 189 MET B CG  1 
ATOM   2579 S  SD  . MET B 2 19  ? -26.648 -12.765 7.929   1   62.63  ? 189 MET B SD  1 
ATOM   2580 C  CE  . MET B 2 19  ? -25.562 -12.026 9.153   1   57.65  ? 189 MET B CE  1 
ATOM   2581 N  N   . GLU B 2 20  ? -28.166 -9.302  4.035   1   38.02  ? 190 GLU B N   1 
ATOM   2582 C  CA  . GLU B 2 20  ? -28.392 -7.971  3.422   1   37.8   ? 190 GLU B CA  1 
ATOM   2583 C  C   . GLU B 2 20  ? -29.583 -7.324  4.13    1   36.17  ? 190 GLU B C   1 
ATOM   2584 O  O   . GLU B 2 20  ? -29.57  -6.101  4.292   1   36.12  ? 190 GLU B O   1 
ATOM   2585 C  CB  . GLU B 2 20  ? -28.523 -8.124  1.907   1   36.57  ? 190 GLU B CB  1 
ATOM   2586 C  CG  . GLU B 2 20  ? -29.925 -8.457  1.415   1   38.72  ? 190 GLU B CG  1 
ATOM   2587 C  CD  . GLU B 2 20  ? -29.989 -8.45   -0.096  1   40.02  ? 190 GLU B CD  1 
ATOM   2588 O  OE1 . GLU B 2 20  ? -29.138 -7.797  -0.714  1   40.24  ? 190 GLU B OE1 1 
ATOM   2589 O  OE2 . GLU B 2 20  ? -30.884 -9.095  -0.656  1   40.19  ? 190 GLU B OE2 1 
ATOM   2590 N  N   . VAL B 2 21  ? -30.554 -8.132  4.54    1   36.29  ? 191 VAL B N   1 
ATOM   2591 C  CA  . VAL B 2 21  ? -31.69  -7.6    5.336   1   38.27  ? 191 VAL B CA  1 
ATOM   2592 C  C   . VAL B 2 21  ? -31.148 -7.192  6.711   1   43.25  ? 191 VAL B C   1 
ATOM   2593 O  O   . VAL B 2 21  ? -31.512 -6.11   7.191   1   45.83  ? 191 VAL B O   1 
ATOM   2594 C  CB  . VAL B 2 21  ? -32.801 -8.654  5.441   1   37.55  ? 191 VAL B CB  1 
ATOM   2595 C  CG1 . VAL B 2 21  ? -33.932 -8.205  6.354   1   36.59  ? 191 VAL B CG1 1 
ATOM   2596 C  CG2 . VAL B 2 21  ? -33.334 -9.046  4.07    1   36.27  ? 191 VAL B CG2 1 
ATOM   2597 N  N   . LYS B 2 22  ? -30.272 -8.005  7.293   1   47.85  ? 192 LYS B N   1 
ATOM   2598 C  CA  . LYS B 2 22  ? -29.784 -7.665  8.62    1   55.19  ? 192 LYS B CA  1 
ATOM   2599 C  C   . LYS B 2 22  ? -28.835 -6.46   8.588   1   53.86  ? 192 LYS B C   1 
ATOM   2600 O  O   . LYS B 2 22  ? -28.725 -5.759  9.586   1   58.33  ? 192 LYS B O   1 
ATOM   2601 C  CB  . LYS B 2 22  ? -29.156 -8.869  9.334   1   68.47  ? 192 LYS B CB  1 
ATOM   2602 C  CG  . LYS B 2 22  ? -30.012 -10.132 9.509   1   80.14  ? 192 LYS B CG  1 
ATOM   2603 C  CD  . LYS B 2 22  ? -29.356 -11.139 10.46   1   93.63  ? 192 LYS B CD  1 
ATOM   2604 C  CE  . LYS B 2 22  ? -29.567 -12.622 10.204  1   94.59  ? 192 LYS B CE  1 
ATOM   2605 N  NZ  . LYS B 2 22  ? -30.908 -13.169 10.442  1   79.65  ? 192 LYS B NZ  1 
ATOM   2606 N  N   . CYS B 2 23  ? -28.128 -6.224  7.47    1   54.35  ? 193 CYS B N   1 
ATOM   2607 C  CA  . CYS B 2 23  ? -27.162 -5.129  7.365   1   51.51  ? 193 CYS B CA  1 
ATOM   2608 C  C   . CYS B 2 23  ? -27.758 -3.913  6.65    1   52.54  ? 193 CYS B C   1 
ATOM   2609 O  O   . CYS B 2 23  ? -27.026 -3.113  6.051   1   59.71  ? 193 CYS B O   1 
ATOM   2610 C  CB  . CYS B 2 23  ? -25.911 -5.544  6.592   1   45.01  ? 193 CYS B CB  1 
ATOM   2611 S  SG  . CYS B 2 23  ? -24.829 -6.703  7.482   1   62.13  ? 193 CYS B SG  1 
ATOM   2612 N  N   . LYS B 2 24  ? -29.088 -3.793  6.68    1   46.22  ? 194 LYS B N   1 
ATOM   2613 C  CA  . LYS B 2 24  ? -29.765 -2.799  5.867   1   48.15  ? 194 LYS B CA  1 
ATOM   2614 C  C   . LYS B 2 24  ? -29.818 -1.484  6.641   1   50.14  ? 194 LYS B C   1 
ATOM   2615 O  O   . LYS B 2 24  ? -30.321 -1.449  7.756   1   56.52  ? 194 LYS B O   1 
ATOM   2616 C  CB  . LYS B 2 24  ? -31.196 -3.247  5.544   1   53.9   ? 194 LYS B CB  1 
ATOM   2617 C  CG  . LYS B 2 24  ? -31.941 -2.251  4.667   1   60.72  ? 194 LYS B CG  1 
ATOM   2618 C  CD  . LYS B 2 24  ? -33.32  -2.577  4.103   1   65.23  ? 194 LYS B CD  1 
ATOM   2619 C  CE  . LYS B 2 24  ? -33.675 -1.523  3.07    1   69.53  ? 194 LYS B CE  1 
ATOM   2620 N  NZ  . LYS B 2 24  ? -34.799 -1.889  2.199   1   68.61  ? 194 LYS B NZ  1 
ATOM   2621 N  N   . PRO B 2 25  ? -29.325 -0.357  6.085   1   46.47  ? 195 PRO B N   1 
ATOM   2622 C  CA  . PRO B 2 25  ? -29.503 0.91    6.763   1   45.33  ? 195 PRO B CA  1 
ATOM   2623 C  C   . PRO B 2 25  ? -30.964 1.307   6.796   1   44.41  ? 195 PRO B C   1 
ATOM   2624 O  O   . PRO B 2 25  ? -31.779 0.761   6.045   1   45.23  ? 195 PRO B O   1 
ATOM   2625 C  CB  . PRO B 2 25  ? -28.663 1.832   5.885   1   44.62  ? 195 PRO B CB  1 
ATOM   2626 C  CG  . PRO B 2 25  ? -27.613 0.928   5.315   1   46.3   ? 195 PRO B CG  1 
ATOM   2627 C  CD  . PRO B 2 25  ? -28.483 -0.218  4.883   1   46.2   ? 195 PRO B CD  1 
ATOM   2628 N  N   . LYS B 2 26  ? -31.309 2.255   7.654   1   47.31  ? 196 LYS B N   1 
ATOM   2629 C  CA  . LYS B 2 26  ? -32.699 2.765   7.698   1   52.91  ? 196 LYS B CA  1 
ATOM   2630 C  C   . LYS B 2 26  ? -32.929 3.673   6.483   1   53.97  ? 196 LYS B C   1 
ATOM   2631 O  O   . LYS B 2 26  ? -32.135 4.604   6.283   1   56.69  ? 196 LYS B O   1 
ATOM   2632 C  CB  . LYS B 2 26  ? -32.923 3.491   9.026   1   61.23  ? 196 LYS B CB  1 
ATOM   2633 C  CG  . LYS B 2 26  ? -34.264 4.194   9.164   1   80.23  ? 196 LYS B CG  1 
ATOM   2634 C  CD  . LYS B 2 26  ? -34.408 5.022   10.436  1   87.62  ? 196 LYS B CD  1 
ATOM   2635 C  CE  . LYS B 2 26  ? -33.103 5.524   10.963  1   88.63  ? 196 LYS B CE  1 
ATOM   2636 N  NZ  . LYS B 2 26  ? -33.224 6.874   11.516  1   93.69  ? 196 LYS B NZ  1 
ATOM   2637 N  N   . VAL B 2 27  ? -33.989 3.419   5.722   1   52.76  ? 197 VAL B N   1 
ATOM   2638 C  CA  . VAL B 2 27  ? -34.232 4.192   4.471   1   54.66  ? 197 VAL B CA  1 
ATOM   2639 C  C   . VAL B 2 27  ? -34.386 5.684   4.783   1   60.23  ? 197 VAL B C   1 
ATOM   2640 O  O   . VAL B 2 27  ? -34.02  6.499   3.926   1   67.4   ? 197 VAL B O   1 
ATOM   2641 C  CB  . VAL B 2 27  ? -35.464 3.646   3.734   1   55.37  ? 197 VAL B CB  1 
ATOM   2642 C  CG1 . VAL B 2 27  ? -35.648 4.298   2.371   1   55.12  ? 197 VAL B CG1 1 
ATOM   2643 C  CG2 . VAL B 2 27  ? -35.402 2.132   3.596   1   57.5   ? 197 VAL B CG2 1 
ATOM   2644 N  N   . GLY B 2 28  ? -34.883 6.037   5.963   1   64     ? 198 GLY B N   1 
ATOM   2645 C  CA  . GLY B 2 28  ? -35.141 7.464   6.225   1   69.99  ? 198 GLY B CA  1 
ATOM   2646 C  C   . GLY B 2 28  ? -34.236 8.059   7.277   1   67.99  ? 198 GLY B C   1 
ATOM   2647 O  O   . GLY B 2 28  ? -34.742 8.835   8.107   1   76.8   ? 198 GLY B O   1 
ATOM   2648 N  N   . TYR B 2 29  ? -32.946 7.754   7.229   1   58.95  ? 199 TYR B N   1 
ATOM   2649 C  CA  . TYR B 2 29  ? -32.045 8.223   8.309   1   52.23  ? 199 TYR B CA  1 
ATOM   2650 C  C   . TYR B 2 29  ? -31.705 9.681   8.083   1   53.36  ? 199 TYR B C   1 
ATOM   2651 O  O   . TYR B 2 29  ? -31.491 10.378  9.082   1   56.14  ? 199 TYR B O   1 
ATOM   2652 C  CB  . TYR B 2 29  ? -30.839 7.282   8.418   1   46.25  ? 199 TYR B CB  1 
ATOM   2653 C  CG  . TYR B 2 29  ? -29.65  7.468   7.487   1   43.95  ? 199 TYR B CG  1 
ATOM   2654 C  CD1 . TYR B 2 29  ? -28.855 8.603   7.547   1   44.35  ? 199 TYR B CD1 1 
ATOM   2655 C  CD2 . TYR B 2 29  ? -29.295 6.476   6.585   1   41.99  ? 199 TYR B CD2 1 
ATOM   2656 C  CE1 . TYR B 2 29  ? -27.778 8.772   6.698   1   44.58  ? 199 TYR B CE1 1 
ATOM   2657 C  CE2 . TYR B 2 29  ? -28.207 6.623   5.745   1   42.65  ? 199 TYR B CE2 1 
ATOM   2658 C  CZ  . TYR B 2 29  ? -27.444 7.774   5.805   1   44.34  ? 199 TYR B CZ  1 
ATOM   2659 O  OH  . TYR B 2 29  ? -26.371 7.938   4.987   1   41.29  ? 199 TYR B OH  1 
ATOM   2660 N  N   . MET B 2 30  ? -31.664 10.13   6.828   1   53.08  ? 200 MET B N   1 
ATOM   2661 C  CA  . MET B 2 30  ? -31.206 11.521  6.571   1   52.55  ? 200 MET B CA  1 
ATOM   2662 C  C   . MET B 2 30  ? -32.233 12.528  7.102   1   56.77  ? 200 MET B C   1 
ATOM   2663 O  O   . MET B 2 30  ? -31.811 13.583  7.593   1   54.1   ? 200 MET B O   1 
ATOM   2664 C  CB  . MET B 2 30  ? -30.944 11.766  5.084   1   51.1   ? 200 MET B CB  1 
ATOM   2665 C  CG  . MET B 2 30  ? -29.882 12.801  4.822   1   52.49  ? 200 MET B CG  1 
ATOM   2666 S  SD  . MET B 2 30  ? -28.303 12.389  5.586   1   54.51  ? 200 MET B SD  1 
ATOM   2667 C  CE  . MET B 2 30  ? -27.597 11.41   4.257   1   51.69  ? 200 MET B CE  1 
ATOM   2668 N  N   . LYS B 2 31  ? -33.519 12.193  7.038   1   63.25  ? 201 LYS B N   1 
ATOM   2669 C  CA  . LYS B 2 31  ? -34.481 13.137  7.595   1   68.52  ? 201 LYS B CA  1 
ATOM   2670 C  C   . LYS B 2 31  ? -34.219 13.357  9.087   1   66.23  ? 201 LYS B C   1 
ATOM   2671 O  O   . LYS B 2 31  ? -34.404 14.459  9.587   1   66.37  ? 201 LYS B O   1 
ATOM   2672 C  CB  . LYS B 2 31  ? -35.931 12.666  7.431   1   77.47  ? 201 LYS B CB  1 
ATOM   2673 C  CG  . LYS B 2 31  ? -36.498 12.334  6.041   1   87.22  ? 201 LYS B CG  1 
ATOM   2674 C  CD  . LYS B 2 31  ? -37.908 11.728  6.127   1   97.6   ? 201 LYS B CD  1 
ATOM   2675 C  CE  . LYS B 2 31  ? -38.112 10.222  6.339   1   99.62  ? 201 LYS B CE  1 
ATOM   2676 N  NZ  . LYS B 2 31  ? -37.679 9.557   7.581   1   90.85  ? 201 LYS B NZ  1 
ATOM   2677 N  N   . LYS B 2 32  ? -33.778 12.314  9.797   1   67.59  ? 202 LYS B N   1 
ATOM   2678 C  CA  . LYS B 2 32  ? -33.574 12.388  11.239  1   70.16  ? 202 LYS B CA  1 
ATOM   2679 C  C   . LYS B 2 32  ? -32.188 12.942  11.565  1   64.45  ? 202 LYS B C   1 
ATOM   2680 O  O   . LYS B 2 32  ? -31.873 13.139  12.729  1   67.22  ? 202 LYS B O   1 
ATOM   2681 C  CB  . LYS B 2 32  ? -33.713 11.016  11.914  1   75.27  ? 202 LYS B CB  1 
ATOM   2682 C  CG  . LYS B 2 32  ? -34.858 10.143  11.416  1   84.4   ? 202 LYS B CG  1 
ATOM   2683 C  CD  . LYS B 2 32  ? -35.581 9.443   12.56   1   89.77  ? 202 LYS B CD  1 
ATOM   2684 C  CE  . LYS B 2 32  ? -36.99  9.14    12.149  1   96.71  ? 202 LYS B CE  1 
ATOM   2685 N  NZ  . LYS B 2 32  ? -37.928 9.282   13.267  1   99.1   ? 202 LYS B NZ  1 
ATOM   2686 N  N   . GLN B 2 33  ? -31.353 13.156  10.541  1   58.14  ? 203 GLN B N   1 
ATOM   2687 C  CA  . GLN B 2 33  ? -30.049 13.777  10.718  1   54.2   ? 203 GLN B CA  1 
ATOM   2688 C  C   . GLN B 2 33  ? -30.229 15.29   10.639  1   55.62  ? 203 GLN B C   1 
ATOM   2689 O  O   . GLN B 2 33  ? -30.624 15.817  9.598   1   55.62  ? 203 GLN B O   1 
ATOM   2690 C  CB  . GLN B 2 33  ? -29.058 13.302  9.658   1   49.52  ? 203 GLN B CB  1 
ATOM   2691 C  CG  . GLN B 2 33  ? -28.571 11.872  9.861   1   45.65  ? 203 GLN B CG  1 
ATOM   2692 C  CD  . GLN B 2 33  ? -27.477 11.741  10.904  1   44.51  ? 203 GLN B CD  1 
ATOM   2693 O  OE1 . GLN B 2 33  ? -26.92  12.729  11.397  1   45.57  ? 203 GLN B OE1 1 
ATOM   2694 N  NE2 . GLN B 2 33  ? -27.105 10.506  11.212  1   41.2   ? 203 GLN B NE2 1 
ATOM   2695 N  N   . PRO B 2 34  ? -30.005 16.022  11.752  1   56.54  ? 204 PRO B N   1 
ATOM   2696 C  CA  . PRO B 2 34  ? -30.344 17.439  11.819  1   57.86  ? 204 PRO B CA  1 
ATOM   2697 C  C   . PRO B 2 34  ? -29.469 18.274  10.897  1   58.37  ? 204 PRO B C   1 
ATOM   2698 O  O   . PRO B 2 34  ? -29.916 19.281  10.384  1   63.37  ? 204 PRO B O   1 
ATOM   2699 C  CB  . PRO B 2 34  ? -30.141 17.805  13.281  1   57.79  ? 204 PRO B CB  1 
ATOM   2700 C  CG  . PRO B 2 34  ? -29.111 16.816  13.751  1   58.14  ? 204 PRO B CG  1 
ATOM   2701 C  CD  . PRO B 2 34  ? -29.422 15.523  13.006  1   57.08  ? 204 PRO B CD  1 
ATOM   2702 N  N   . ASP B 2 35  ? -28.241 17.83   10.64   1   58.49  ? 205 ASP B N   1 
ATOM   2703 C  CA  . ASP B 2 35  ? -27.227 18.737  10.137  1   58.26  ? 205 ASP B CA  1 
ATOM   2704 C  C   . ASP B 2 35  ? -26.578 18.225  8.852   1   58.22  ? 205 ASP B C   1 
ATOM   2705 O  O   . ASP B 2 35  ? -25.7   18.893  8.302   1   61.72  ? 205 ASP B O   1 
ATOM   2706 C  CB  . ASP B 2 35  ? -26.149 18.936  11.182  1   57.71  ? 205 ASP B CB  1 
ATOM   2707 C  CG  . ASP B 2 35  ? -25.278 20.136  10.896  1   59.47  ? 205 ASP B CG  1 
ATOM   2708 O  OD1 . ASP B 2 35  ? -25.868 21.221  10.749  1   58.83  ? 205 ASP B OD1 1 
ATOM   2709 O  OD2 . ASP B 2 35  ? -24.044 19.946  10.786  1   60.99  ? 205 ASP B OD2 1 
ATOM   2710 N  N   . ILE B 2 36  ? -26.999 17.046  8.383   1   52.67  ? 206 ILE B N   1 
ATOM   2711 C  CA  . ILE B 2 36  ? -26.463 16.522  7.144   1   52.26  ? 206 ILE B CA  1 
ATOM   2712 C  C   . ILE B 2 36  ? -27.607 16.079  6.223   1   52.66  ? 206 ILE B C   1 
ATOM   2713 O  O   . ILE B 2 36  ? -28.733 15.859  6.672   1   51.47  ? 206 ILE B O   1 
ATOM   2714 C  CB  . ILE B 2 36  ? -25.388 15.453  7.422   1   50     ? 206 ILE B CB  1 
ATOM   2715 C  CG1 . ILE B 2 36  ? -25.968 14.23   8.084   1   47.47  ? 206 ILE B CG1 1 
ATOM   2716 C  CG2 . ILE B 2 36  ? -24.256 16.043  8.264   1   50.51  ? 206 ILE B CG2 1 
ATOM   2717 C  CD1 . ILE B 2 36  ? -24.997 13.073  8.138   1   46.7   ? 206 ILE B CD1 1 
ATOM   2718 N  N   . THR B 2 37  ? -27.286 15.981  4.919   1   52.01  ? 207 THR B N   1 
ATOM   2719 C  CA  . THR B 2 37  ? -28.252 15.856  3.829   1   50.67  ? 207 THR B CA  1 
ATOM   2720 C  C   . THR B 2 37  ? -27.754 14.79   2.854   1   46.58  ? 207 THR B C   1 
ATOM   2721 O  O   . THR B 2 37  ? -26.592 14.392  2.909   1   44.51  ? 207 THR B O   1 
ATOM   2722 C  CB  . THR B 2 37  ? -28.368 17.192  3.089   1   51.91  ? 207 THR B CB  1 
ATOM   2723 O  OG1 . THR B 2 37  ? -27.022 17.407  2.66    1   52.31  ? 207 THR B OG1 1 
ATOM   2724 C  CG2 . THR B 2 37  ? -28.845 18.331  3.969   1   53.45  ? 207 THR B CG2 1 
ATOM   2725 N  N   . ASN B 2 38  ? -28.644 14.363  1.948   1   46.05  ? 208 ASN B N   1 
ATOM   2726 C  CA  . ASN B 2 38  ? -28.292 13.486  0.844   1   45.44  ? 208 ASN B CA  1 
ATOM   2727 C  C   . ASN B 2 38  ? -27.101 14.04   0.052   1   45.73  ? 208 ASN B C   1 
ATOM   2728 O  O   . ASN B 2 38  ? -26.176 13.279  -0.258  1   45.88  ? 208 ASN B O   1 
ATOM   2729 C  CB  . ASN B 2 38  ? -29.501 13.107  -0.001  1   46.27  ? 208 ASN B CB  1 
ATOM   2730 C  CG  . ASN B 2 38  ? -30.551 12.357  0.795   1   49.32  ? 208 ASN B CG  1 
ATOM   2731 O  OD1 . ASN B 2 38  ? -30.234 11.495  1.628   1   48.67  ? 208 ASN B OD1 1 
ATOM   2732 N  ND2 . ASN B 2 38  ? -31.814 12.637  0.522   1   48.94  ? 208 ASN B ND2 1 
ATOM   2733 N  N   . SER B 2 39  ? -27.087 15.359  -0.192  1   44.92  ? 209 SER B N   1 
ATOM   2734 C  CA  . SER B 2 39  ? -26.047 16.006  -0.979  1   48.21  ? 209 SER B CA  1 
ATOM   2735 C  C   . SER B 2 39  ? -24.692 15.896  -0.304  1   48.3   ? 209 SER B C   1 
ATOM   2736 O  O   . SER B 2 39  ? -23.69  15.66   -0.986  1   48.7   ? 209 SER B O   1 
ATOM   2737 C  CB  . SER B 2 39  ? -26.344 17.449  -1.249  1   51.13  ? 209 SER B CB  1 
ATOM   2738 O  OG  . SER B 2 39  ? -27.561 17.498  -1.968  1   57.65  ? 209 SER B OG  1 
ATOM   2739 N  N   . MET B 2 40  ? -24.678 16.118  1.021   1   48.19  ? 210 MET B N   1 
ATOM   2740 C  CA  . MET B 2 40  ? -23.451 15.978  1.789   1   46.94  ? 210 MET B CA  1 
ATOM   2741 C  C   . MET B 2 40  ? -22.889 14.572  1.639   1   44.6   ? 210 MET B C   1 
ATOM   2742 O  O   . MET B 2 40  ? -21.697 14.422  1.348   1   44.37  ? 210 MET B O   1 
ATOM   2743 C  CB  . MET B 2 40  ? -23.65  16.36   3.249   1   47.77  ? 210 MET B CB  1 
ATOM   2744 C  CG  . MET B 2 40  ? -23.76  17.857  3.39    1   50.5   ? 210 MET B CG  1 
ATOM   2745 S  SD  . MET B 2 40  ? -24.087 18.34   5.091   1   52.08  ? 210 MET B SD  1 
ATOM   2746 C  CE  . MET B 2 40  ? -24.465 20.075  4.81    1   52.61  ? 210 MET B CE  1 
ATOM   2747 N  N   . ARG B 2 41  ? -23.78  13.577  1.772   1   42.43  ? 211 ARG B N   1 
ATOM   2748 C  CA  . ARG B 2 41  ? -23.375 12.176  1.73    1   42.06  ? 211 ARG B CA  1 
ATOM   2749 C  C   . ARG B 2 41  ? -22.849 11.845  0.331   1   41.63  ? 211 ARG B C   1 
ATOM   2750 O  O   . ARG B 2 41  ? -21.883 11.103  0.194   1   40.16  ? 211 ARG B O   1 
ATOM   2751 C  CB  . ARG B 2 41  ? -24.512 11.264  2.218   1   40     ? 211 ARG B CB  1 
ATOM   2752 C  CG  . ARG B 2 41  ? -24.382 9.789   1.866   1   36.95  ? 211 ARG B CG  1 
ATOM   2753 C  CD  . ARG B 2 41  ? -25.743 9.117   1.953   1   37.19  ? 211 ARG B CD  1 
ATOM   2754 N  NE  . ARG B 2 41  ? -25.554 7.68    1.715   1   36.71  ? 211 ARG B NE  1 
ATOM   2755 C  CZ  . ARG B 2 41  ? -25.23  7.162   0.536   1   36.9   ? 211 ARG B CZ  1 
ATOM   2756 N  NH1 . ARG B 2 41  ? -25.317 7.915   -0.556  1   36.35  ? 211 ARG B NH1 1 
ATOM   2757 N  NH2 . ARG B 2 41  ? -24.878 5.883   0.445   1   33.98  ? 211 ARG B NH2 1 
ATOM   2758 N  N   . ALA B 2 42  ? -23.497 12.426  -0.692  1   45.33  ? 212 ALA B N   1 
ATOM   2759 C  CA  . ALA B 2 42  ? -23.122 12.304  -2.098  1   44.3   ? 212 ALA B CA  1 
ATOM   2760 C  C   . ALA B 2 42  ? -21.701 12.827  -2.324  1   44.05  ? 212 ALA B C   1 
ATOM   2761 O  O   . ALA B 2 42  ? -20.872 12.168  -2.949  1   44.04  ? 212 ALA B O   1 
ATOM   2762 C  CB  . ALA B 2 42  ? -24.13  13.042  -2.956  1   41.57  ? 212 ALA B CB  1 
ATOM   2763 N  N   . ILE B 2 43  ? -21.408 14.006  -1.778  1   43.73  ? 213 ILE B N   1 
ATOM   2764 C  CA  . ILE B 2 43  ? -20.045 14.499  -1.833  1   43.24  ? 213 ILE B CA  1 
ATOM   2765 C  C   . ILE B 2 43  ? -19.096 13.491  -1.17   1   43.26  ? 213 ILE B C   1 
ATOM   2766 O  O   . ILE B 2 43  ? -18.044 13.19   -1.722  1   46.85  ? 213 ILE B O   1 
ATOM   2767 C  CB  . ILE B 2 43  ? -19.961 15.907  -1.222  1   44.38  ? 213 ILE B CB  1 
ATOM   2768 C  CG1 . ILE B 2 43  ? -20.712 16.926  -2.087  1   45.1   ? 213 ILE B CG1 1 
ATOM   2769 C  CG2 . ILE B 2 43  ? -18.512 16.332  -0.963  1   43.74  ? 213 ILE B CG2 1 
ATOM   2770 C  CD1 . ILE B 2 43  ? -20.915 18.27   -1.408  1   45.89  ? 213 ILE B CD1 1 
ATOM   2771 N  N   . LEU B 2 44  ? -19.466 12.943  -0.008  1   40.39  ? 214 LEU B N   1 
ATOM   2772 C  CA  . LEU B 2 44  ? -18.576 12.059  0.728   1   39.11  ? 214 LEU B CA  1 
ATOM   2773 C  C   . LEU B 2 44  ? -18.298 10.778  -0.06   1   38.29  ? 214 LEU B C   1 
ATOM   2774 O  O   . LEU B 2 44  ? -17.152 10.337  -0.168  1   38.56  ? 214 LEU B O   1 
ATOM   2775 C  CB  . LEU B 2 44  ? -19.152 11.701  2.093   1   37.06  ? 214 LEU B CB  1 
ATOM   2776 C  CG  . LEU B 2 44  ? -18.317 10.695  2.892   1   35.37  ? 214 LEU B CG  1 
ATOM   2777 C  CD1 . LEU B 2 44  ? -17.02  11.344  3.356   1   33.96  ? 214 LEU B CD1 1 
ATOM   2778 C  CD2 . LEU B 2 44  ? -19.121 10.112  4.059   1   34.65  ? 214 LEU B CD2 1 
ATOM   2779 N  N   . VAL B 2 45  ? -19.364 10.154  -0.561  1   37.57  ? 215 VAL B N   1 
ATOM   2780 C  CA  . VAL B 2 45  ? -19.211 8.912   -1.294  1   36.59  ? 215 VAL B CA  1 
ATOM   2781 C  C   . VAL B 2 45  ? -18.398 9.182   -2.556  1   39.43  ? 215 VAL B C   1 
ATOM   2782 O  O   . VAL B 2 45  ? -17.588 8.348   -2.963  1   39.82  ? 215 VAL B O   1 
ATOM   2783 C  CB  . VAL B 2 45  ? -20.554 8.222   -1.591  1   35.62  ? 215 VAL B CB  1 
ATOM   2784 C  CG1 . VAL B 2 45  ? -20.358 7.023   -2.504  1   35.01  ? 215 VAL B CG1 1 
ATOM   2785 C  CG2 . VAL B 2 45  ? -21.259 7.794   -0.302  1   33.98  ? 215 VAL B CG2 1 
ATOM   2786 N  N   . ASP B 2 46  ? -18.572 10.379  -3.14   1   40.27  ? 216 ASP B N   1 
ATOM   2787 C  CA  . ASP B 2 46  ? -17.869 10.698  -4.369  1   39.41  ? 216 ASP B CA  1 
ATOM   2788 C  C   . ASP B 2 46  ? -16.374 10.791  -4.097  1   39.69  ? 216 ASP B C   1 
ATOM   2789 O  O   . ASP B 2 46  ? -15.563 10.358  -4.907  1   40.58  ? 216 ASP B O   1 
ATOM   2790 C  CB  . ASP B 2 46  ? -18.412 11.935  -5.059  1   39.86  ? 216 ASP B CB  1 
ATOM   2791 C  CG  . ASP B 2 46  ? -17.653 12.33   -6.319  1   40.21  ? 216 ASP B CG  1 
ATOM   2792 O  OD1 . ASP B 2 46  ? -16.632 13.038  -6.182  1   39.15  ? 216 ASP B OD1 1 
ATOM   2793 O  OD2 . ASP B 2 46  ? -18.037 11.851  -7.418  1   40.59  ? 216 ASP B OD2 1 
ATOM   2794 N  N   . TRP B 2 47  ? -16.036 11.371  -2.949  1   40.74  ? 217 TRP B N   1 
ATOM   2795 C  CA  . TRP B 2 47  ? -14.663 11.477  -2.484  1   41.84  ? 217 TRP B CA  1 
ATOM   2796 C  C   . TRP B 2 47  ? -14.05  10.105  -2.199  1   40.82  ? 217 TRP B C   1 
ATOM   2797 O  O   . TRP B 2 47  ? -12.886 9.864   -2.524  1   45     ? 217 TRP B O   1 
ATOM   2798 C  CB  . TRP B 2 47  ? -14.612 12.389  -1.252  1   40.71  ? 217 TRP B CB  1 
ATOM   2799 C  CG  . TRP B 2 47  ? -13.273 12.437  -0.572  1   41.35  ? 217 TRP B CG  1 
ATOM   2800 C  CD1 . TRP B 2 47  ? -12.165 13.071  -1.035  1   42.42  ? 217 TRP B CD1 1 
ATOM   2801 C  CD2 . TRP B 2 47  ? -12.911 11.861  0.711   1   41.47  ? 217 TRP B CD2 1 
ATOM   2802 N  NE1 . TRP B 2 47  ? -11.144 12.953  -0.131  1   43.92  ? 217 TRP B NE1 1 
ATOM   2803 C  CE2 . TRP B 2 47  ? -11.562 12.216  0.945   1   42.33  ? 217 TRP B CE2 1 
ATOM   2804 C  CE3 . TRP B 2 47  ? -13.589 11.101  1.679   1   39.26  ? 217 TRP B CE3 1 
ATOM   2805 C  CZ2 . TRP B 2 47  ? -10.871 11.822  2.088   1   42.29  ? 217 TRP B CZ2 1 
ATOM   2806 C  CZ3 . TRP B 2 47  ? -12.913 10.723  2.821   1   39.62  ? 217 TRP B CZ3 1 
ATOM   2807 C  CH2 . TRP B 2 47  ? -11.571 11.073  3.014   1   42.62  ? 217 TRP B CH2 1 
ATOM   2808 N  N   . LEU B 2 48  ? -14.82  9.199   -1.591  1   40.34  ? 218 LEU B N   1 
ATOM   2809 C  CA  . LEU B 2 48  ? -14.281 7.883   -1.264  1   39     ? 218 LEU B CA  1 
ATOM   2810 C  C   . LEU B 2 48  ? -13.909 7.155   -2.547  1   38.58  ? 218 LEU B C   1 
ATOM   2811 O  O   . LEU B 2 48  ? -12.923 6.42    -2.59   1   40.63  ? 218 LEU B O   1 
ATOM   2812 C  CB  . LEU B 2 48  ? -15.247 7.073   -0.399  1   35.67  ? 218 LEU B CB  1 
ATOM   2813 C  CG  . LEU B 2 48  ? -15.44  7.637   1.008   1   35.35  ? 218 LEU B CG  1 
ATOM   2814 C  CD1 . LEU B 2 48  ? -16.5   6.91    1.797   1   33.31  ? 218 LEU B CD1 1 
ATOM   2815 C  CD2 . LEU B 2 48  ? -14.092 7.564   1.713   1   34.32  ? 218 LEU B CD2 1 
ATOM   2816 N  N   . VAL B 2 49  ? -14.708 7.388   -3.591  1   38.54  ? 219 VAL B N   1 
ATOM   2817 C  CA  . VAL B 2 49  ? -14.442 6.812   -4.896  1   38.77  ? 219 VAL B CA  1 
ATOM   2818 C  C   . VAL B 2 49  ? -13.031 7.209   -5.34   1   41.53  ? 219 VAL B C   1 
ATOM   2819 O  O   . VAL B 2 49  ? -12.241 6.334   -5.715  1   41.86  ? 219 VAL B O   1 
ATOM   2820 C  CB  . VAL B 2 49  ? -15.552 7.129   -5.915  1   38.08  ? 219 VAL B CB  1 
ATOM   2821 C  CG1 . VAL B 2 49  ? -15.181 6.699   -7.331  1   38.54  ? 219 VAL B CG1 1 
ATOM   2822 C  CG2 . VAL B 2 49  ? -16.838 6.43    -5.495  1   36.03  ? 219 VAL B CG2 1 
ATOM   2823 N  N   . GLU B 2 50  ? -12.688 8.5     -5.209  1   42.01  ? 220 GLU B N   1 
ATOM   2824 C  CA  . GLU B 2 50  ? -11.37  8.958   -5.605  1   44.67  ? 220 GLU B CA  1 
ATOM   2825 C  C   . GLU B 2 50  ? -10.316 8.372   -4.674  1   46.45  ? 220 GLU B C   1 
ATOM   2826 O  O   . GLU B 2 50  ? -9.261  7.935   -5.131  1   46.69  ? 220 GLU B O   1 
ATOM   2827 C  CB  . GLU B 2 50  ? -11.161 10.453  -5.449  1   47.45  ? 220 GLU B CB  1 
ATOM   2828 C  CG  . GLU B 2 50  ? -12.332 11.26   -5.968  1   52.89  ? 220 GLU B CG  1 
ATOM   2829 C  CD  . GLU B 2 50  ? -11.862 12.686  -6.156  1   58.31  ? 220 GLU B CD  1 
ATOM   2830 O  OE1 . GLU B 2 50  ? -11.89  13.139  -7.324  1   60.34  ? 220 GLU B OE1 1 
ATOM   2831 O  OE2 . GLU B 2 50  ? -11.472 13.318  -5.153  1   60.28  ? 220 GLU B OE2 1 
ATOM   2832 N  N   . VAL B 2 51  ? -10.587 8.372   -3.361  1   47.06  ? 221 VAL B N   1 
ATOM   2833 C  CA  . VAL B 2 51  ? -9.654  7.72    -2.446  1   46.53  ? 221 VAL B CA  1 
ATOM   2834 C  C   . VAL B 2 51  ? -9.338  6.301   -2.952  1   45.71  ? 221 VAL B C   1 
ATOM   2835 O  O   . VAL B 2 51  ? -8.16   5.946   -3.07   1   45.34  ? 221 VAL B O   1 
ATOM   2836 C  CB  . VAL B 2 51  ? -10.159 7.752   -0.987  1   44.61  ? 221 VAL B CB  1 
ATOM   2837 C  CG1 . VAL B 2 51  ? -9.38   6.817   -0.059  1   41.06  ? 221 VAL B CG1 1 
ATOM   2838 C  CG2 . VAL B 2 51  ? -10.168 9.169   -0.44   1   44.01  ? 221 VAL B CG2 1 
ATOM   2839 N  N   . GLY B 2 52  ? -10.393 5.52    -3.278  1   42.22  ? 222 GLY B N   1 
ATOM   2840 C  CA  . GLY B 2 52  ? -10.273 4.177   -3.838  1   40.6   ? 222 GLY B CA  1 
ATOM   2841 C  C   . GLY B 2 52  ? -9.432  4.11    -5.121  1   44.08  ? 222 GLY B C   1 
ATOM   2842 O  O   . GLY B 2 52  ? -8.643  3.184   -5.31   1   45.29  ? 222 GLY B O   1 
ATOM   2843 N  N   . GLU B 2 53  ? -9.576  5.113   -5.991  1   46.03  ? 223 GLU B N   1 
ATOM   2844 C  CA  . GLU B 2 53  ? -8.823  5.206   -7.234  1   47.8   ? 223 GLU B CA  1 
ATOM   2845 C  C   . GLU B 2 53  ? -7.36   5.529   -6.977  1   50.18  ? 223 GLU B C   1 
ATOM   2846 O  O   . GLU B 2 53  ? -6.486  4.883   -7.546  1   53.71  ? 223 GLU B O   1 
ATOM   2847 C  CB  . GLU B 2 53  ? -9.481  6.181   -8.205  1   51.76  ? 223 GLU B CB  1 
ATOM   2848 C  CG  . GLU B 2 53  ? -10.598 5.487   -8.975  1   58.49  ? 223 GLU B CG  1 
ATOM   2849 C  CD  . GLU B 2 53  ? -9.97   4.453   -9.909  1   72.12  ? 223 GLU B CD  1 
ATOM   2850 O  OE1 . GLU B 2 53  ? -9.297  4.936   -10.877 1   68.27  ? 223 GLU B OE1 1 
ATOM   2851 O  OE2 . GLU B 2 53  ? -10.137 3.201   -9.686  1   71.8   ? 223 GLU B OE2 1 
ATOM   2852 N  N   . GLU B 2 54  ? -7.119  6.518   -6.11   1   53.13  ? 224 GLU B N   1 
ATOM   2853 C  CA  . GLU B 2 54  ? -5.803  6.946   -5.649  1   54.37  ? 224 GLU B CA  1 
ATOM   2854 C  C   . GLU B 2 54  ? -5.004  5.791   -5.04   1   49.61  ? 224 GLU B C   1 
ATOM   2855 O  O   . GLU B 2 54  ? -3.81   5.695   -5.298  1   49.46  ? 224 GLU B O   1 
ATOM   2856 C  CB  . GLU B 2 54  ? -5.944  8.061   -4.607  1   60.62  ? 224 GLU B CB  1 
ATOM   2857 C  CG  . GLU B 2 54  ? -4.614  8.681   -4.177  1   68.67  ? 224 GLU B CG  1 
ATOM   2858 C  CD  . GLU B 2 54  ? -3.965  9.55    -5.245  1   79.29  ? 224 GLU B CD  1 
ATOM   2859 O  OE1 . GLU B 2 54  ? -4.619  9.774   -6.297  1   85.19  ? 224 GLU B OE1 1 
ATOM   2860 O  OE2 . GLU B 2 54  ? -2.817  10.014  -5.044  1   82.41  ? 224 GLU B OE2 1 
ATOM   2861 N  N   . TYR B 2 55  ? -5.648  4.946   -4.216  1   46.75  ? 225 TYR B N   1 
ATOM   2862 C  CA  . TYR B 2 55  ? -4.934  3.909   -3.481  1   44.3   ? 225 TYR B CA  1 
ATOM   2863 C  C   . TYR B 2 55  ? -5.085  2.579   -4.202  1   44.92  ? 225 TYR B C   1 
ATOM   2864 O  O   . TYR B 2 55  ? -4.611  1.553   -3.723  1   43.53  ? 225 TYR B O   1 
ATOM   2865 C  CB  . TYR B 2 55  ? -5.297  3.912   -1.993  1   42.5   ? 225 TYR B CB  1 
ATOM   2866 C  CG  . TYR B 2 55  ? -4.656  5.102   -1.302  1   44.98  ? 225 TYR B CG  1 
ATOM   2867 C  CD1 . TYR B 2 55  ? -3.357  5.043   -0.809  1   44.51  ? 225 TYR B CD1 1 
ATOM   2868 C  CD2 . TYR B 2 55  ? -5.323  6.318   -1.216  1   48.76  ? 225 TYR B CD2 1 
ATOM   2869 C  CE1 . TYR B 2 55  ? -2.746  6.15    -0.237  1   47.07  ? 225 TYR B CE1 1 
ATOM   2870 C  CE2 . TYR B 2 55  ? -4.726  7.431   -0.638  1   50.76  ? 225 TYR B CE2 1 
ATOM   2871 C  CZ  . TYR B 2 55  ? -3.438  7.346   -0.138  1   49.37  ? 225 TYR B CZ  1 
ATOM   2872 O  OH  . TYR B 2 55  ? -2.881  8.446   0.456   1   51.49  ? 225 TYR B OH  1 
ATOM   2873 N  N   . LYS B 2 56  ? -5.758  2.628   -5.363  1   49.05  ? 226 LYS B N   1 
ATOM   2874 C  CA  . LYS B 2 56  ? -6.054  1.455   -6.172  1   48.34  ? 226 LYS B CA  1 
ATOM   2875 C  C   . LYS B 2 56  ? -6.614  0.352   -5.275  1   45.9   ? 226 LYS B C   1 
ATOM   2876 O  O   . LYS B 2 56  ? -6.045  -0.731  -5.212  1   43.02  ? 226 LYS B O   1 
ATOM   2877 C  CB  . LYS B 2 56  ? -4.833  0.951   -6.94   1   49.12  ? 226 LYS B CB  1 
ATOM   2878 C  CG  . LYS B 2 56  ? -4.09   2.006   -7.725  1   58.3   ? 226 LYS B CG  1 
ATOM   2879 C  CD  . LYS B 2 56  ? -2.95   1.383   -8.518  1   70.96  ? 226 LYS B CD  1 
ATOM   2880 C  CE  . LYS B 2 56  ? -1.728  2.254   -8.608  1   83.5   ? 226 LYS B CE  1 
ATOM   2881 N  NZ  . LYS B 2 56  ? -2.045  3.666   -8.834  1   91.38  ? 226 LYS B NZ  1 
ATOM   2882 N  N   . LEU B 2 57  ? -7.716  0.674   -4.577  1   43.08  ? 227 LEU B N   1 
ATOM   2883 C  CA  . LEU B 2 57  ? -8.429  -0.211  -3.664  1   41.16  ? 227 LEU B CA  1 
ATOM   2884 C  C   . LEU B 2 57  ? -9.427  -1.032  -4.471  1   39.61  ? 227 LEU B C   1 
ATOM   2885 O  O   . LEU B 2 57  ? -9.749  -0.682  -5.598  1   40.42  ? 227 LEU B O   1 
ATOM   2886 C  CB  . LEU B 2 57  ? -9.156  0.613   -2.595  1   36.63  ? 227 LEU B CB  1 
ATOM   2887 C  CG  . LEU B 2 57  ? -8.258  1.435   -1.666  1   37.76  ? 227 LEU B CG  1 
ATOM   2888 C  CD1 . LEU B 2 57  ? -9.108  2.122   -0.612  1   37.76  ? 227 LEU B CD1 1 
ATOM   2889 C  CD2 . LEU B 2 57  ? -7.115  0.611   -1.053  1   35.53  ? 227 LEU B CD2 1 
ATOM   2890 N  N   . GLN B 2 58  ? -9.933  -2.109  -3.874  1   38.53  ? 228 GLN B N   1 
ATOM   2891 C  CA  . GLN B 2 58  ? -10.973 -2.882  -4.516  1   37.92  ? 228 GLN B CA  1 
ATOM   2892 C  C   . GLN B 2 58  ? -12.259 -2.062  -4.541  1   38.29  ? 228 GLN B C   1 
ATOM   2893 O  O   . GLN B 2 58  ? -12.487 -1.207  -3.675  1   40.94  ? 228 GLN B O   1 
ATOM   2894 C  CB  . GLN B 2 58  ? -11.149 -4.19   -3.749  1   39.83  ? 228 GLN B CB  1 
ATOM   2895 C  CG  . GLN B 2 58  ? -9.945  -5.13   -3.8    1   42.86  ? 228 GLN B CG  1 
ATOM   2896 C  CD  . GLN B 2 58  ? -9.589  -5.585  -5.199  1   43.81  ? 228 GLN B CD  1 
ATOM   2897 O  OE1 . GLN B 2 58  ? -10.404 -6.159  -5.926  1   44.21  ? 228 GLN B OE1 1 
ATOM   2898 N  NE2 . GLN B 2 58  ? -8.352  -5.335  -5.589  1   42.98  ? 228 GLN B NE2 1 
ATOM   2899 N  N   . ASN B 2 59  ? -13.11  -2.363  -5.53   1   37.4   ? 229 ASN B N   1 
ATOM   2900 C  CA  . ASN B 2 59  ? -14.483 -1.877  -5.563  1   36.25  ? 229 ASN B CA  1 
ATOM   2901 C  C   . ASN B 2 59  ? -15.268 -2.424  -4.373  1   36.26  ? 229 ASN B C   1 
ATOM   2902 O  O   . ASN B 2 59  ? -16.142 -1.757  -3.831  1   41.62  ? 229 ASN B O   1 
ATOM   2903 C  CB  . ASN B 2 59  ? -15.173 -2.207  -6.881  1   36.33  ? 229 ASN B CB  1 
ATOM   2904 C  CG  . ASN B 2 59  ? -14.542 -1.476  -8.048  1   36.96  ? 229 ASN B CG  1 
ATOM   2905 O  OD1 . ASN B 2 59  ? -13.777 -0.515  -7.874  1   32.92  ? 229 ASN B OD1 1 
ATOM   2906 N  ND2 . ASN B 2 59  ? -14.845 -1.941  -9.248  1   37.79  ? 229 ASN B ND2 1 
ATOM   2907 N  N   . GLU B 2 60  ? -14.979 -3.656  -3.974  1   35.4   ? 230 GLU B N   1 
ATOM   2908 C  CA  . GLU B 2 60  ? -15.636 -4.228  -2.813  1   34.88  ? 230 GLU B CA  1 
ATOM   2909 C  C   . GLU B 2 60  ? -15.363 -3.393  -1.553  1   34.32  ? 230 GLU B C   1 
ATOM   2910 O  O   . GLU B 2 60  ? -16.253 -3.216  -0.727  1   37.49  ? 230 GLU B O   1 
ATOM   2911 C  CB  . GLU B 2 60  ? -15.202 -5.69   -2.729  1   32.44  ? 230 GLU B CB  1 
ATOM   2912 C  CG  . GLU B 2 60  ? -15.721 -6.418  -1.5    1   30.18  ? 230 GLU B CG  1 
ATOM   2913 C  CD  . GLU B 2 60  ? -17.216 -6.587  -1.552  1   32.61  ? 230 GLU B CD  1 
ATOM   2914 O  OE1 . GLU B 2 60  ? -17.845 -6.381  -2.633  1   34.21  ? 230 GLU B OE1 1 
ATOM   2915 O  OE2 . GLU B 2 60  ? -17.748 -6.86   -0.451  1   33.13  ? 230 GLU B OE2 1 
ATOM   2916 N  N   . THR B 2 61  ? -14.143 -2.883  -1.385  1   34.38  ? 231 THR B N   1 
ATOM   2917 C  CA  . THR B 2 61  ? -13.803 -2.084  -0.211  1   35.54  ? 231 THR B CA  1 
ATOM   2918 C  C   . THR B 2 61  ? -14.695 -0.844  -0.183  1   36.58  ? 231 THR B C   1 
ATOM   2919 O  O   . THR B 2 61  ? -15.221 -0.501  0.87    1   32.89  ? 231 THR B O   1 
ATOM   2920 C  CB  . THR B 2 61  ? -12.327 -1.671  -0.254  1   37.7   ? 231 THR B CB  1 
ATOM   2921 O  OG1 . THR B 2 61  ? -11.473 -2.77   -0.567  1   38.59  ? 231 THR B OG1 1 
ATOM   2922 C  CG2 . THR B 2 61  ? -11.851 -1.02   1.028   1   34.42  ? 231 THR B CG2 1 
ATOM   2923 N  N   . LEU B 2 62  ? -14.83  -0.165  -1.343  1   38.49  ? 232 LEU B N   1 
ATOM   2924 C  CA  . LEU B 2 62  ? -15.702 0.996   -1.506  1   36.49  ? 232 LEU B CA  1 
ATOM   2925 C  C   . LEU B 2 62  ? -17.129 0.682   -1.04   1   36.14  ? 232 LEU B C   1 
ATOM   2926 O  O   . LEU B 2 62  ? -17.683 1.426   -0.231  1   39.33  ? 232 LEU B O   1 
ATOM   2927 C  CB  . LEU B 2 62  ? -15.655 1.512   -2.951  1   35.67  ? 232 LEU B CB  1 
ATOM   2928 C  CG  . LEU B 2 62  ? -16.705 2.555   -3.379  1   32.7   ? 232 LEU B CG  1 
ATOM   2929 C  CD1 . LEU B 2 62  ? -16.512 3.851   -2.612  1   30.65  ? 232 LEU B CD1 1 
ATOM   2930 C  CD2 . LEU B 2 62  ? -16.697 2.833   -4.884  1   30.86  ? 232 LEU B CD2 1 
ATOM   2931 N  N   . HIS B 2 63  ? -17.729 -0.397  -1.565  1   31.8   ? 233 HIS B N   1 
ATOM   2932 C  CA  . HIS B 2 63  ? -19.088 -0.775  -1.209  1   29.88  ? 233 HIS B CA  1 
ATOM   2933 C  C   . HIS B 2 63  ? -19.233 -1.089  0.286   1   34.2   ? 233 HIS B C   1 
ATOM   2934 O  O   . HIS B 2 63  ? -20.244 -0.71   0.893   1   34.45  ? 233 HIS B O   1 
ATOM   2935 C  CB  . HIS B 2 63  ? -19.562 -1.949  -2.058  1   29.18  ? 233 HIS B CB  1 
ATOM   2936 C  CG  . HIS B 2 63  ? -19.937 -1.638  -3.474  1   31.6   ? 233 HIS B CG  1 
ATOM   2937 N  ND1 . HIS B 2 63  ? -19.014 -1.402  -4.479  1   32.78  ? 233 HIS B ND1 1 
ATOM   2938 C  CD2 . HIS B 2 63  ? -21.134 -1.557  -4.055  1   30.29  ? 233 HIS B CD2 1 
ATOM   2939 C  CE1 . HIS B 2 63  ? -19.652 -1.174  -5.621  1   32.16  ? 233 HIS B CE1 1 
ATOM   2940 N  NE2 . HIS B 2 63  ? -20.936 -1.25   -5.385  1   32.38  ? 233 HIS B NE2 1 
ATOM   2941 N  N   . LEU B 2 64  ? -18.252 -1.81   0.877   1   34.39  ? 234 LEU B N   1 
ATOM   2942 C  CA  . LEU B 2 64  ? -18.239 -2.08   2.312   1   33.09  ? 234 LEU B CA  1 
ATOM   2943 C  C   . LEU B 2 64  ? -18.256 -0.758  3.087   1   34.61  ? 234 LEU B C   1 
ATOM   2944 O  O   . LEU B 2 64  ? -18.975 -0.625  4.072   1   34.42  ? 234 LEU B O   1 
ATOM   2945 C  CB  . LEU B 2 64  ? -17.089 -2.976  2.77    1   31.77  ? 234 LEU B CB  1 
ATOM   2946 C  CG  . LEU B 2 64  ? -17.103 -4.424  2.256   1   35.42  ? 234 LEU B CG  1 
ATOM   2947 C  CD1 . LEU B 2 64  ? -15.761 -5.136  2.455   1   31.21  ? 234 LEU B CD1 1 
ATOM   2948 C  CD2 . LEU B 2 64  ? -18.239 -5.253  2.869   1   36.19  ? 234 LEU B CD2 1 
ATOM   2949 N  N   . ALA B 2 65  ? -17.501 0.24    2.615   1   33.61  ? 235 ALA B N   1 
ATOM   2950 C  CA  . ALA B 2 65  ? -17.332 1.474   3.361   1   36.08  ? 235 ALA B CA  1 
ATOM   2951 C  C   . ALA B 2 65  ? -18.65  2.254   3.398   1   39.98  ? 235 ALA B C   1 
ATOM   2952 O  O   . ALA B 2 65  ? -19.039 2.796   4.442   1   47.12  ? 235 ALA B O   1 
ATOM   2953 C  CB  . ALA B 2 65  ? -16.213 2.303   2.746   1   34.64  ? 235 ALA B CB  1 
ATOM   2954 N  N   . VAL B 2 66  ? -19.326 2.306   2.245   1   36.19  ? 236 VAL B N   1 
ATOM   2955 C  CA  . VAL B 2 66  ? -20.604 2.98    2.127   1   34.79  ? 236 VAL B CA  1 
ATOM   2956 C  C   . VAL B 2 66  ? -21.606 2.279   3.054   1   35.94  ? 236 VAL B C   1 
ATOM   2957 O  O   . VAL B 2 66  ? -22.379 2.959   3.731   1   41.66  ? 236 VAL B O   1 
ATOM   2958 C  CB  . VAL B 2 66  ? -21.092 3.084   0.658   1   32.28  ? 236 VAL B CB  1 
ATOM   2959 C  CG1 . VAL B 2 66  ? -22.508 3.652   0.547   1   31.4   ? 236 VAL B CG1 1 
ATOM   2960 C  CG2 . VAL B 2 66  ? -20.129 3.879   -0.222  1   29.69  ? 236 VAL B CG2 1 
ATOM   2961 N  N   . ASN B 2 67  ? -21.589 0.935   3.103   1   33.26  ? 237 ASN B N   1 
ATOM   2962 C  CA  . ASN B 2 67  ? -22.466 0.169   3.985   1   33.75  ? 237 ASN B CA  1 
ATOM   2963 C  C   . ASN B 2 67  ? -22.249 0.595   5.447   1   34.2   ? 237 ASN B C   1 
ATOM   2964 O  O   . ASN B 2 67  ? -23.205 0.854   6.186   1   33.65  ? 237 ASN B O   1 
ATOM   2965 C  CB  . ASN B 2 67  ? -22.273 -1.34   3.821   1   33.72  ? 237 ASN B CB  1 
ATOM   2966 C  CG  . ASN B 2 67  ? -23.106 -2.127  4.81    1   35.96  ? 237 ASN B CG  1 
ATOM   2967 O  OD1 . ASN B 2 67  ? -22.613 -2.497  5.885   1   38.14  ? 237 ASN B OD1 1 
ATOM   2968 N  ND2 . ASN B 2 67  ? -24.382 -2.339  4.517   1   36.78  ? 237 ASN B ND2 1 
ATOM   2969 N  N   . TYR B 2 68  ? -20.978 0.694   5.856   1   32.63  ? 238 TYR B N   1 
ATOM   2970 C  CA  . TYR B 2 68  ? -20.645 1.044   7.224   1   34.72  ? 238 TYR B CA  1 
ATOM   2971 C  C   . TYR B 2 68  ? -21.166 2.446   7.544   1   35.44  ? 238 TYR B C   1 
ATOM   2972 O  O   . TYR B 2 68  ? -21.678 2.683   8.65    1   34.34  ? 238 TYR B O   1 
ATOM   2973 C  CB  . TYR B 2 68  ? -19.135 0.978   7.478   1   35.93  ? 238 TYR B CB  1 
ATOM   2974 C  CG  . TYR B 2 68  ? -18.514 -0.377  7.201   1   33.37  ? 238 TYR B CG  1 
ATOM   2975 C  CD1 . TYR B 2 68  ? -19.295 -1.532  7.112   1   34.48  ? 238 TYR B CD1 1 
ATOM   2976 C  CD2 . TYR B 2 68  ? -17.148 -0.493  7.044   1   31.54  ? 238 TYR B CD2 1 
ATOM   2977 C  CE1 . TYR B 2 68  ? -18.734 -2.772  6.834   1   32.87  ? 238 TYR B CE1 1 
ATOM   2978 C  CE2 . TYR B 2 68  ? -16.573 -1.72   6.777   1   31.87  ? 238 TYR B CE2 1 
ATOM   2979 C  CZ  . TYR B 2 68  ? -17.36  -2.858  6.67    1   33.67  ? 238 TYR B CZ  1 
ATOM   2980 O  OH  . TYR B 2 68  ? -16.729 -4.033  6.377   1   31.68  ? 238 TYR B OH  1 
ATOM   2981 N  N   . ILE B 2 69  ? -21.005 3.363   6.575   1   34.92  ? 239 ILE B N   1 
ATOM   2982 C  CA  . ILE B 2 69  ? -21.366 4.757   6.798   1   36.67  ? 239 ILE B CA  1 
ATOM   2983 C  C   . ILE B 2 69  ? -22.868 4.853   7.061   1   38.7   ? 239 ILE B C   1 
ATOM   2984 O  O   . ILE B 2 69  ? -23.303 5.483   8.036   1   38.82  ? 239 ILE B O   1 
ATOM   2985 C  CB  . ILE B 2 69  ? -20.915 5.67    5.642   1   34.65  ? 239 ILE B CB  1 
ATOM   2986 C  CG1 . ILE B 2 69  ? -19.397 5.748   5.532   1   33.14  ? 239 ILE B CG1 1 
ATOM   2987 C  CG2 . ILE B 2 69  ? -21.523 7.063   5.817   1   34.5   ? 239 ILE B CG2 1 
ATOM   2988 C  CD1 . ILE B 2 69  ? -18.894 6.356   4.237   1   32.71  ? 239 ILE B CD1 1 
ATOM   2989 N  N   . ASP B 2 70  ? -23.632 4.205   6.174   1   35.75  ? 240 ASP B N   1 
ATOM   2990 C  CA  . ASP B 2 70  ? -25.073 4.325   6.172   1   36.4   ? 240 ASP B CA  1 
ATOM   2991 C  C   . ASP B 2 70  ? -25.669 3.704   7.431   1   36.45  ? 240 ASP B C   1 
ATOM   2992 O  O   . ASP B 2 70  ? -26.642 4.229   7.983   1   38.2   ? 240 ASP B O   1 
ATOM   2993 C  CB  . ASP B 2 70  ? -25.631 3.708   4.909   1   37.77  ? 240 ASP B CB  1 
ATOM   2994 C  CG  . ASP B 2 70  ? -25.507 4.576   3.674   1   40.16  ? 240 ASP B CG  1 
ATOM   2995 O  OD1 . ASP B 2 70  ? -25.469 5.819   3.828   1   43.58  ? 240 ASP B OD1 1 
ATOM   2996 O  OD2 . ASP B 2 70  ? -25.399 3.991   2.578   1   42.7   ? 240 ASP B OD2 1 
ATOM   2997 N  N   . ARG B 2 71  ? -25.09  2.578   7.854   1   34.8   ? 241 ARG B N   1 
ATOM   2998 C  CA  . ARG B 2 71  ? -25.497 1.894   9.075   1   36.5   ? 241 ARG B CA  1 
ATOM   2999 C  C   . ARG B 2 71  ? -25.117 2.723   10.297  1   38.37  ? 241 ARG B C   1 
ATOM   3000 O  O   . ARG B 2 71  ? -25.841 2.757   11.292  1   42.22  ? 241 ARG B O   1 
ATOM   3001 C  CB  . ARG B 2 71  ? -24.833 0.516   9.19    1   35.7   ? 241 ARG B CB  1 
ATOM   3002 C  CG  . ARG B 2 71  ? -25.658 -0.564  8.509   1   37.8   ? 241 ARG B CG  1 
ATOM   3003 C  CD  . ARG B 2 71  ? -24.803 -1.769  8.158   1   35.61  ? 241 ARG B CD  1 
ATOM   3004 N  NE  . ARG B 2 71  ? -24.314 -2.423  9.365   1   39.05  ? 241 ARG B NE  1 
ATOM   3005 C  CZ  . ARG B 2 71  ? -23.286 -3.277  9.393   1   39     ? 241 ARG B CZ  1 
ATOM   3006 N  NH1 . ARG B 2 71  ? -22.628 -3.597  8.287   1   35.85  ? 241 ARG B NH1 1 
ATOM   3007 N  NH2 . ARG B 2 71  ? -22.921 -3.791  10.559  1   40.55  ? 241 ARG B NH2 1 
ATOM   3008 N  N   . PHE B 2 72  ? -23.946 3.358   10.223  1   38.13  ? 242 PHE B N   1 
ATOM   3009 C  CA  . PHE B 2 72  ? -23.499 4.222   11.297  1   38.33  ? 242 PHE B CA  1 
ATOM   3010 C  C   . PHE B 2 72  ? -24.446 5.423   11.387  1   40.84  ? 242 PHE B C   1 
ATOM   3011 O  O   . PHE B 2 72  ? -24.965 5.747   12.452  1   40.37  ? 242 PHE B O   1 
ATOM   3012 C  CB  . PHE B 2 72  ? -22.013 4.543   11.092  1   35.66  ? 242 PHE B CB  1 
ATOM   3013 C  CG  . PHE B 2 72  ? -21.427 5.34    12.25   1   36.64  ? 242 PHE B CG  1 
ATOM   3014 C  CD1 . PHE B 2 72  ? -21.606 6.724   12.327  1   37.19  ? 242 PHE B CD1 1 
ATOM   3015 C  CD2 . PHE B 2 72  ? -20.724 4.714   13.279  1   34.92  ? 242 PHE B CD2 1 
ATOM   3016 C  CE1 . PHE B 2 72  ? -21.114 7.458   13.401  1   36.9   ? 242 PHE B CE1 1 
ATOM   3017 C  CE2 . PHE B 2 72  ? -20.206 5.472   14.331  1   36.08  ? 242 PHE B CE2 1 
ATOM   3018 C  CZ  . PHE B 2 72  ? -20.421 6.832   14.408  1   36.28  ? 242 PHE B CZ  1 
ATOM   3019 N  N   . LEU B 2 73  ? -24.665 6.086   10.247  1   42.55  ? 243 LEU B N   1 
ATOM   3020 C  CA  . LEU B 2 73  ? -25.518 7.258   10.16   1   43.68  ? 243 LEU B CA  1 
ATOM   3021 C  C   . LEU B 2 73  ? -26.957 6.929   10.55   1   43.82  ? 243 LEU B C   1 
ATOM   3022 O  O   . LEU B 2 73  ? -27.693 7.839   10.885  1   48.7   ? 243 LEU B O   1 
ATOM   3023 C  CB  . LEU B 2 73  ? -25.441 7.883   8.762   1   45     ? 243 LEU B CB  1 
ATOM   3024 C  CG  . LEU B 2 73  ? -24.144 8.619   8.397   1   42.87  ? 243 LEU B CG  1 
ATOM   3025 C  CD1 . LEU B 2 73  ? -24.287 9.445   7.137   1   40.91  ? 243 LEU B CD1 1 
ATOM   3026 C  CD2 . LEU B 2 73  ? -23.637 9.506   9.532   1   45.37  ? 243 LEU B CD2 1 
ATOM   3027 N  N   . SER B 2 74  ? -27.361 5.651   10.529  1   45.04  ? 244 SER B N   1 
ATOM   3028 C  CA  . SER B 2 74  ? -28.712 5.258   10.936  1   47.74  ? 244 SER B CA  1 
ATOM   3029 C  C   . SER B 2 74  ? -28.941 5.416   12.449  1   49.43  ? 244 SER B C   1 
ATOM   3030 O  O   . SER B 2 74  ? -30.037 5.785   12.855  1   52.1   ? 244 SER B O   1 
ATOM   3031 C  CB  . SER B 2 74  ? -29.075 3.847   10.471  1   46.45  ? 244 SER B CB  1 
ATOM   3032 O  OG  . SER B 2 74  ? -29.132 3.723   9.055   1   44.56  ? 244 SER B OG  1 
ATOM   3033 N  N   . SER B 2 75  ? -27.919 5.167   13.285  1   47.53  ? 245 SER B N   1 
ATOM   3034 C  CA  . SER B 2 75  ? -28.053 5.296   14.731  1   48.12  ? 245 SER B CA  1 
ATOM   3035 C  C   . SER B 2 75  ? -27.343 6.522   15.309  1   51.1   ? 245 SER B C   1 
ATOM   3036 O  O   . SER B 2 75  ? -27.662 6.905   16.429  1   55.04  ? 245 SER B O   1 
ATOM   3037 C  CB  . SER B 2 75  ? -27.613 4.067   15.453  1   46.63  ? 245 SER B CB  1 
ATOM   3038 O  OG  . SER B 2 75  ? -26.459 3.53    14.825  1   46.26  ? 245 SER B OG  1 
ATOM   3039 N  N   . MET B 2 76  ? -26.403 7.142   14.578  1   48.13  ? 246 MET B N   1 
ATOM   3040 C  CA  . MET B 2 76  ? -25.588 8.192   15.181  1   47.71  ? 246 MET B CA  1 
ATOM   3041 C  C   . MET B 2 76  ? -25.8   9.51    14.442  1   48.7   ? 246 MET B C   1 
ATOM   3042 O  O   . MET B 2 76  ? -25.621 9.559   13.216  1   47.34  ? 246 MET B O   1 
ATOM   3043 C  CB  . MET B 2 76  ? -24.089 7.873   15.099  1   45.52  ? 246 MET B CB  1 
ATOM   3044 C  CG  . MET B 2 76  ? -23.682 6.595   15.782  1   45.15  ? 246 MET B CG  1 
ATOM   3045 S  SD  . MET B 2 76  ? -23.962 6.615   17.554  1   49.13  ? 246 MET B SD  1 
ATOM   3046 C  CE  . MET B 2 76  ? -22.532 7.467   18.228  1   45.58  ? 246 MET B CE  1 
ATOM   3047 N  N   . SER B 2 77  ? -26.163 10.561  15.197  1   47.97  ? 247 SER B N   1 
ATOM   3048 C  CA  . SER B 2 77  ? -26.219 11.906  14.65   1   50.23  ? 247 SER B CA  1 
ATOM   3049 C  C   . SER B 2 77  ? -24.802 12.426  14.47   1   50.83  ? 247 SER B C   1 
ATOM   3050 O  O   . SER B 2 77  ? -23.981 12.299  15.38   1   52.81  ? 247 SER B O   1 
ATOM   3051 C  CB  . SER B 2 77  ? -26.984 12.857  15.514  1   51.28  ? 247 SER B CB  1 
ATOM   3052 O  OG  . SER B 2 77  ? -28.346 12.508  15.438  1   52.33  ? 247 SER B OG  1 
ATOM   3053 N  N   . VAL B 2 78  ? -24.557 13.034  13.306  1   49.59  ? 248 VAL B N   1 
ATOM   3054 C  CA  . VAL B 2 78  ? -23.235 13.532  12.969  1   49.79  ? 248 VAL B CA  1 
ATOM   3055 C  C   . VAL B 2 78  ? -23.359 14.951  12.419  1   51.11  ? 248 VAL B C   1 
ATOM   3056 O  O   . VAL B 2 78  ? -24.241 15.224  11.604  1   54.85  ? 248 VAL B O   1 
ATOM   3057 C  CB  . VAL B 2 78  ? -22.566 12.558  11.978  1   48.29  ? 248 VAL B CB  1 
ATOM   3058 C  CG1 . VAL B 2 78  ? -21.156 13.003  11.622  1   50.47  ? 248 VAL B CG1 1 
ATOM   3059 C  CG2 . VAL B 2 78  ? -22.519 11.131  12.523  1   44.91  ? 248 VAL B CG2 1 
ATOM   3060 N  N   . LEU B 2 79  ? -22.501 15.856  12.913  1   51.05  ? 249 LEU B N   1 
ATOM   3061 C  CA  . LEU B 2 79  ? -22.378 17.202  12.37   1   52.76  ? 249 LEU B CA  1 
ATOM   3062 C  C   . LEU B 2 79  ? -21.677 17.154  11.003  1   51.81  ? 249 LEU B C   1 
ATOM   3063 O  O   . LEU B 2 79  ? -20.857 16.269  10.732  1   48.08  ? 249 LEU B O   1 
ATOM   3064 C  CB  . LEU B 2 79  ? -21.618 18.065  13.377  1   54.03  ? 249 LEU B CB  1 
ATOM   3065 C  CG  . LEU B 2 79  ? -22.342 18.4    14.69   1   58.24  ? 249 LEU B CG  1 
ATOM   3066 C  CD1 . LEU B 2 79  ? -21.431 19.298  15.519  1   59.38  ? 249 LEU B CD1 1 
ATOM   3067 C  CD2 . LEU B 2 79  ? -23.727 19.051  14.526  1   56.34  ? 249 LEU B CD2 1 
ATOM   3068 N  N   . ARG B 2 80  ? -22.001 18.114  10.134  1   51.57  ? 250 ARG B N   1 
ATOM   3069 C  CA  . ARG B 2 80  ? -21.407 18.156  8.806   1   51.83  ? 250 ARG B CA  1 
ATOM   3070 C  C   . ARG B 2 80  ? -19.876 18.136  8.881   1   54.19  ? 250 ARG B C   1 
ATOM   3071 O  O   . ARG B 2 80  ? -19.24  17.492  8.039   1   54.87  ? 250 ARG B O   1 
ATOM   3072 C  CB  . ARG B 2 80  ? -21.885 19.393  8.051   1   53.12  ? 250 ARG B CB  1 
ATOM   3073 C  CG  . ARG B 2 80  ? -21.284 20.637  8.686   1   57.38  ? 250 ARG B CG  1 
ATOM   3074 C  CD  . ARG B 2 80  ? -21.91  21.864  8.091   1   60.98  ? 250 ARG B CD  1 
ATOM   3075 N  NE  . ARG B 2 80  ? -23.359 21.701  8.216   1   63.71  ? 250 ARG B NE  1 
ATOM   3076 C  CZ  . ARG B 2 80  ? -24.268 22.469  7.644   1   64.55  ? 250 ARG B CZ  1 
ATOM   3077 N  NH1 . ARG B 2 80  ? -25.529 22.089  7.667   1   65.23  ? 250 ARG B NH1 1 
ATOM   3078 N  NH2 . ARG B 2 80  ? -23.914 23.557  6.996   1   64.55  ? 250 ARG B NH2 1 
ATOM   3079 N  N   . GLY B 2 81  ? -19.297 18.819  9.893   1   54.13  ? 251 GLY B N   1 
ATOM   3080 C  CA  . GLY B 2 81  ? -17.853 18.91   10.1    1   52.94  ? 251 GLY B CA  1 
ATOM   3081 C  C   . GLY B 2 81  ? -17.145 17.581  10.417  1   52.64  ? 251 GLY B C   1 
ATOM   3082 O  O   . GLY B 2 81  ? -15.914 17.537  10.437  1   53     ? 251 GLY B O   1 
ATOM   3083 N  N   . LYS B 2 82  ? -17.907 16.496  10.661  1   49.5   ? 252 LYS B N   1 
ATOM   3084 C  CA  . LYS B 2 82  ? -17.364 15.238  11.15   1   46.11  ? 252 LYS B CA  1 
ATOM   3085 C  C   . LYS B 2 82  ? -17.837 14.091  10.273  1   45     ? 252 LYS B C   1 
ATOM   3086 O  O   . LYS B 2 82  ? -17.477 12.935  10.513  1   45.56  ? 252 LYS B O   1 
ATOM   3087 C  CB  . LYS B 2 82  ? -17.78  14.994  12.602  1   45.51  ? 252 LYS B CB  1 
ATOM   3088 C  CG  . LYS B 2 82  ? -17.132 15.972  13.549  1   48.7   ? 252 LYS B CG  1 
ATOM   3089 C  CD  . LYS B 2 82  ? -15.804 15.407  14.041  1   49.58  ? 252 LYS B CD  1 
ATOM   3090 C  CE  . LYS B 2 82  ? -14.973 16.452  14.721  1   52.78  ? 252 LYS B CE  1 
ATOM   3091 N  NZ  . LYS B 2 82  ? -15.751 17.327  15.598  1   54.96  ? 252 LYS B NZ  1 
ATOM   3092 N  N   . LEU B 2 83  ? -18.635 14.42   9.252   1   46.2   ? 253 LEU B N   1 
ATOM   3093 C  CA  . LEU B 2 83  ? -19.079 13.425  8.288   1   44.2   ? 253 LEU B CA  1 
ATOM   3094 C  C   . LEU B 2 83  ? -17.872 12.765  7.625   1   45.76  ? 253 LEU B C   1 
ATOM   3095 O  O   . LEU B 2 83  ? -17.894 11.553  7.38    1   46.16  ? 253 LEU B O   1 
ATOM   3096 C  CB  . LEU B 2 83  ? -20.011 14.021  7.241   1   41.67  ? 253 LEU B CB  1 
ATOM   3097 C  CG  . LEU B 2 83  ? -20.589 13.001  6.251   1   38.96  ? 253 LEU B CG  1 
ATOM   3098 C  CD1 . LEU B 2 83  ? -21.236 11.811  6.92    1   36.18  ? 253 LEU B CD1 1 
ATOM   3099 C  CD2 . LEU B 2 83  ? -21.609 13.711  5.379   1   40.09  ? 253 LEU B CD2 1 
ATOM   3100 N  N   . GLN B 2 84  ? -16.838 13.571  7.34    1   44.42  ? 254 GLN B N   1 
ATOM   3101 C  CA  . GLN B 2 84  ? -15.658 13.082  6.647   1   45.91  ? 254 GLN B CA  1 
ATOM   3102 C  C   . GLN B 2 84  ? -14.832 12.186  7.568   1   48.24  ? 254 GLN B C   1 
ATOM   3103 O  O   . GLN B 2 84  ? -14.175 11.248  7.115   1   49.54  ? 254 GLN B O   1 
ATOM   3104 C  CB  . GLN B 2 84  ? -14.813 14.216  6.071   1   47.53  ? 254 GLN B CB  1 
ATOM   3105 C  CG  . GLN B 2 84  ? -13.849 13.763  4.984   1   48.67  ? 254 GLN B CG  1 
ATOM   3106 C  CD  . GLN B 2 84  ? -12.822 14.81   4.595   1   51.74  ? 254 GLN B CD  1 
ATOM   3107 O  OE1 . GLN B 2 84  ? -12.648 15.848  5.247   1   53.6   ? 254 GLN B OE1 1 
ATOM   3108 N  NE2 . GLN B 2 84  ? -12.089 14.513  3.533   1   49.64  ? 254 GLN B NE2 1 
ATOM   3109 N  N   . LEU B 2 85  ? -14.847 12.473  8.871   1   49.83  ? 255 LEU B N   1 
ATOM   3110 C  CA  . LEU B 2 85  ? -14.148 11.602  9.8     1   47.8   ? 255 LEU B CA  1 
ATOM   3111 C  C   . LEU B 2 85  ? -14.839 10.243  9.838   1   45.91  ? 255 LEU B C   1 
ATOM   3112 O  O   . LEU B 2 85  ? -14.19  9.206   9.774   1   49.59  ? 255 LEU B O   1 
ATOM   3113 C  CB  . LEU B 2 85  ? -14.029 12.235  11.182  1   50.1   ? 255 LEU B CB  1 
ATOM   3114 C  CG  . LEU B 2 85  ? -13.214 11.432  12.201  1   50.47  ? 255 LEU B CG  1 
ATOM   3115 C  CD1 . LEU B 2 85  ? -11.871 10.909  11.747  1   46.97  ? 255 LEU B CD1 1 
ATOM   3116 C  CD2 . LEU B 2 85  ? -13.096 12.251  13.47   1   54.27  ? 255 LEU B CD2 1 
ATOM   3117 N  N   . VAL B 2 86  ? -16.17  10.255  9.877   1   44.24  ? 256 VAL B N   1 
ATOM   3118 C  CA  . VAL B 2 86  ? -16.925 9.013   9.828   1   42.42  ? 256 VAL B CA  1 
ATOM   3119 C  C   . VAL B 2 86  ? -16.497 8.206   8.605   1   41.92  ? 256 VAL B C   1 
ATOM   3120 O  O   . VAL B 2 86  ? -16.167 7.034   8.739   1   44.96  ? 256 VAL B O   1 
ATOM   3121 C  CB  . VAL B 2 86  ? -18.449 9.221   9.863   1   41.49  ? 256 VAL B CB  1 
ATOM   3122 C  CG1 . VAL B 2 86  ? -19.214 7.918   9.716   1   40.07  ? 256 VAL B CG1 1 
ATOM   3123 C  CG2 . VAL B 2 86  ? -18.869 9.902   11.151  1   41.25  ? 256 VAL B CG2 1 
ATOM   3124 N  N   . GLY B 2 87  ? -16.472 8.835   7.42    1   41.8   ? 257 GLY B N   1 
ATOM   3125 C  CA  . GLY B 2 87  ? -16.172 8.167   6.155   1   37.08  ? 257 GLY B CA  1 
ATOM   3126 C  C   . GLY B 2 87  ? -14.737 7.645   6.077   1   36.3   ? 257 GLY B C   1 
ATOM   3127 O  O   . GLY B 2 87  ? -14.497 6.558   5.551   1   34.72  ? 257 GLY B O   1 
ATOM   3128 N  N   . THR B 2 88  ? -13.782 8.413   6.616   1   36.78  ? 258 THR B N   1 
ATOM   3129 C  CA  . THR B 2 88  ? -12.393 7.992   6.636   1   37.75  ? 258 THR B CA  1 
ATOM   3130 C  C   . THR B 2 88  ? -12.258 6.736   7.487   1   38.78  ? 258 THR B C   1 
ATOM   3131 O  O   . THR B 2 88  ? -11.613 5.79    7.046   1   38.62  ? 258 THR B O   1 
ATOM   3132 C  CB  . THR B 2 88  ? -11.472 9.088   7.173   1   39.49  ? 258 THR B CB  1 
ATOM   3133 O  OG1 . THR B 2 88  ? -11.774 10.255  6.416   1   41.54  ? 258 THR B OG1 1 
ATOM   3134 C  CG2 . THR B 2 88  ? -10.005 8.695   7.096   1   38.71  ? 258 THR B CG2 1 
ATOM   3135 N  N   . ALA B 2 89  ? -12.855 6.728   8.7     1   40.25  ? 259 ALA B N   1 
ATOM   3136 C  CA  . ALA B 2 89  ? -12.744 5.558   9.572   1   38.92  ? 259 ALA B CA  1 
ATOM   3137 C  C   . ALA B 2 89  ? -13.39  4.358   8.89    1   35.85  ? 259 ALA B C   1 
ATOM   3138 O  O   . ALA B 2 89  ? -12.866 3.247   8.922   1   35.54  ? 259 ALA B O   1 
ATOM   3139 C  CB  . ALA B 2 89  ? -13.345 5.812   10.938  1   39.88  ? 259 ALA B CB  1 
ATOM   3140 N  N   . ALA B 2 90  ? -14.526 4.618   8.251   1   33.9   ? 260 ALA B N   1 
ATOM   3141 C  CA  . ALA B 2 90  ? -15.24  3.597   7.511   1   34.04  ? 260 ALA B CA  1 
ATOM   3142 C  C   . ALA B 2 90  ? -14.298 2.945   6.496   1   34.3   ? 260 ALA B C   1 
ATOM   3143 O  O   . ALA B 2 90  ? -14.203 1.727   6.443   1   34.44  ? 260 ALA B O   1 
ATOM   3144 C  CB  . ALA B 2 90  ? -16.472 4.213   6.863   1   31.49  ? 260 ALA B CB  1 
ATOM   3145 N  N   . MET B 2 91  ? -13.619 3.769   5.688   1   34.61  ? 261 MET B N   1 
ATOM   3146 C  CA  . MET B 2 91  ? -12.833 3.323   4.558   1   33.34  ? 261 MET B CA  1 
ATOM   3147 C  C   . MET B 2 91  ? -11.609 2.594   5.099   1   35.26  ? 261 MET B C   1 
ATOM   3148 O  O   . MET B 2 91  ? -11.196 1.562   4.564   1   37.02  ? 261 MET B O   1 
ATOM   3149 C  CB  . MET B 2 91  ? -12.411 4.527   3.708   1   36.49  ? 261 MET B CB  1 
ATOM   3150 C  CG  . MET B 2 91  ? -11.947 4.171   2.305   1   41.61  ? 261 MET B CG  1 
ATOM   3151 S  SD  . MET B 2 91  ? -13.218 3.503   1.202   1   43     ? 261 MET B SD  1 
ATOM   3152 C  CE  . MET B 2 91  ? -12.336 3.063   -0.303  1   48.99  ? 261 MET B CE  1 
ATOM   3153 N  N   . LEU B 2 92  ? -11.055 3.1     6.206   1   35.01  ? 262 LEU B N   1 
ATOM   3154 C  CA  . LEU B 2 92  ? -9.966  2.405   6.87    1   34.87  ? 262 LEU B CA  1 
ATOM   3155 C  C   . LEU B 2 92  ? -10.386 0.987   7.289   1   34.99  ? 262 LEU B C   1 
ATOM   3156 O  O   . LEU B 2 92  ? -9.628  0.037   7.097   1   35.85  ? 262 LEU B O   1 
ATOM   3157 C  CB  . LEU B 2 92  ? -9.442  3.247   8.031   1   35.67  ? 262 LEU B CB  1 
ATOM   3158 C  CG  . LEU B 2 92  ? -8.542  2.488   9.015   1   37.75  ? 262 LEU B CG  1 
ATOM   3159 C  CD1 . LEU B 2 92  ? -7.231  2.054   8.359   1   38.29  ? 262 LEU B CD1 1 
ATOM   3160 C  CD2 . LEU B 2 92  ? -8.302  3.248   10.302  1   37.23  ? 262 LEU B CD2 1 
ATOM   3161 N  N   . LEU B 2 93  ? -11.593 0.833   7.858   1   32.64  ? 263 LEU B N   1 
ATOM   3162 C  CA  . LEU B 2 93  ? -12.057 -0.47   8.325   1   31.81  ? 263 LEU B CA  1 
ATOM   3163 C  C   . LEU B 2 93  ? -12.309 -1.403  7.147   1   31.64  ? 263 LEU B C   1 
ATOM   3164 O  O   . LEU B 2 93  ? -11.901 -2.567  7.182   1   32.24  ? 263 LEU B O   1 
ATOM   3165 C  CB  . LEU B 2 93  ? -13.329 -0.355  9.156   1   31.98  ? 263 LEU B CB  1 
ATOM   3166 C  CG  . LEU B 2 93  ? -13.141 0.138   10.589  1   34.64  ? 263 LEU B CG  1 
ATOM   3167 C  CD1 . LEU B 2 93  ? -14.509 0.518   11.14   1   33.84  ? 263 LEU B CD1 1 
ATOM   3168 C  CD2 . LEU B 2 93  ? -12.501 -0.993  11.383  1   34.61  ? 263 LEU B CD2 1 
ATOM   3169 N  N   . ALA B 2 94  ? -13.046 -0.903  6.146   1   29.55  ? 264 ALA B N   1 
ATOM   3170 C  CA  . ALA B 2 94  ? -13.217 -1.592  4.879   1   28.98  ? 264 ALA B CA  1 
ATOM   3171 C  C   . ALA B 2 94  ? -11.87  -2.136  4.384   1   30.62  ? 264 ALA B C   1 
ATOM   3172 O  O   . ALA B 2 94  ? -11.758 -3.314  4.073   1   29.25  ? 264 ALA B O   1 
ATOM   3173 C  CB  . ALA B 2 94  ? -13.854 -0.66   3.857   1   26.79  ? 264 ALA B CB  1 
ATOM   3174 N  N   . SER B 2 95  ? -10.845 -1.272  4.303   1   33.27  ? 265 SER B N   1 
ATOM   3175 C  CA  . SER B 2 95  ? -9.562  -1.65   3.732   1   32.74  ? 265 SER B CA  1 
ATOM   3176 C  C   . SER B 2 95  ? -8.945  -2.804  4.509   1   34.91  ? 265 SER B C   1 
ATOM   3177 O  O   . SER B 2 95  ? -8.467  -3.752  3.898   1   37.84  ? 265 SER B O   1 
ATOM   3178 C  CB  . SER B 2 95  ? -8.634  -0.495  3.697   1   35.22  ? 265 SER B CB  1 
ATOM   3179 O  OG  . SER B 2 95  ? -9.15   0.513   2.839   1   40.35  ? 265 SER B OG  1 
ATOM   3180 N  N   . LYS B 2 96  ? -8.92   -2.688  5.848   1   34.9   ? 266 LYS B N   1 
ATOM   3181 C  CA  . LYS B 2 96  ? -8.347  -3.709  6.702   1   33.42  ? 266 LYS B CA  1 
ATOM   3182 C  C   . LYS B 2 96  ? -9.168  -4.99   6.57    1   31.74  ? 266 LYS B C   1 
ATOM   3183 O  O   . LYS B 2 96  ? -8.599  -6.065  6.546   1   34.61  ? 266 LYS B O   1 
ATOM   3184 C  CB  . LYS B 2 96  ? -8.268  -3.285  8.166   1   34.7   ? 266 LYS B CB  1 
ATOM   3185 C  CG  . LYS B 2 96  ? -7.381  -2.113  8.53    1   35.27  ? 266 LYS B CG  1 
ATOM   3186 C  CD  . LYS B 2 96  ? -7.48   -1.88   10.039  1   35     ? 266 LYS B CD  1 
ATOM   3187 C  CE  . LYS B 2 96  ? -6.875  -0.615  10.546  1   35.81  ? 266 LYS B CE  1 
ATOM   3188 N  NZ  . LYS B 2 96  ? -6.796  -0.634  12.012  1   36.86  ? 266 LYS B NZ  1 
ATOM   3189 N  N   . PHE B 2 97  ? -10.483 -4.893  6.41    1   29.58  ? 267 PHE B N   1 
ATOM   3190 C  CA  . PHE B 2 97  ? -11.27  -6.088  6.163   1   29.45  ? 267 PHE B CA  1 
ATOM   3191 C  C   . PHE B 2 97  ? -10.879 -6.78   4.856   1   31.29  ? 267 PHE B C   1 
ATOM   3192 O  O   . PHE B 2 97  ? -10.662 -8.017  4.831   1   30.62  ? 267 PHE B O   1 
ATOM   3193 C  CB  . PHE B 2 97  ? -12.764 -5.785  6.081   1   29.15  ? 267 PHE B CB  1 
ATOM   3194 C  CG  . PHE B 2 97  ? -13.638 -7.042  6.1     1   30.78  ? 267 PHE B CG  1 
ATOM   3195 C  CD1 . PHE B 2 97  ? -13.911 -7.707  7.301   1   30.96  ? 267 PHE B CD1 1 
ATOM   3196 C  CD2 . PHE B 2 97  ? -14.207 -7.548  4.928   1   28.51  ? 267 PHE B CD2 1 
ATOM   3197 C  CE1 . PHE B 2 97  ? -14.698 -8.859  7.322   1   30.83  ? 267 PHE B CE1 1 
ATOM   3198 C  CE2 . PHE B 2 97  ? -15.005 -8.691  4.953   1   29.51  ? 267 PHE B CE2 1 
ATOM   3199 C  CZ  . PHE B 2 97  ? -15.256 -9.346  6.148   1   30.13  ? 267 PHE B CZ  1 
ATOM   3200 N  N   . GLU B 2 98  ? -10.802 -5.97   3.78    1   30.99  ? 268 GLU B N   1 
ATOM   3201 C  CA  . GLU B 2 98  ? -10.993 -6.474  2.427   1   31.45  ? 268 GLU B CA  1 
ATOM   3202 C  C   . GLU B 2 98  ? -9.701  -6.53   1.608   1   32.95  ? 268 GLU B C   1 
ATOM   3203 O  O   . GLU B 2 98  ? -9.632  -7.336  0.677   1   30.66  ? 268 GLU B O   1 
ATOM   3204 C  CB  . GLU B 2 98  ? -12.063 -5.688  1.678   1   31.99  ? 268 GLU B CB  1 
ATOM   3205 C  CG  . GLU B 2 98  ? -12.469 -6.319  0.346   1   34.95  ? 268 GLU B CG  1 
ATOM   3206 C  CD  . GLU B 2 98  ? -13.113 -7.697  0.437   1   37.78  ? 268 GLU B CD  1 
ATOM   3207 O  OE1 . GLU B 2 98  ? -13.899 -7.961  1.391   1   38.13  ? 268 GLU B OE1 1 
ATOM   3208 O  OE2 . GLU B 2 98  ? -12.824 -8.505  -0.469  1   36.59  ? 268 GLU B OE2 1 
ATOM   3209 N  N   . GLU B 2 99  ? -8.695  -5.71   1.97    1   33.03  ? 269 GLU B N   1 
ATOM   3210 C  CA  . GLU B 2 99  ? -7.512  -5.523  1.152   1   32.58  ? 269 GLU B CA  1 
ATOM   3211 C  C   . GLU B 2 99  ? -6.37   -6.381  1.65    1   36.38  ? 269 GLU B C   1 
ATOM   3212 O  O   . GLU B 2 99  ? -6.185  -6.5    2.858   1   39.24  ? 269 GLU B O   1 
ATOM   3213 C  CB  . GLU B 2 99  ? -7.023  -4.083  1.252   1   35.46  ? 269 GLU B CB  1 
ATOM   3214 C  CG  . GLU B 2 99  ? -7.981  -3.073  0.626   1   36.32  ? 269 GLU B CG  1 
ATOM   3215 C  CD  . GLU B 2 99  ? -8.056  -3.093  -0.889  1   38.73  ? 269 GLU B CD  1 
ATOM   3216 O  OE1 . GLU B 2 99  ? -7.105  -3.606  -1.543  1   41.24  ? 269 GLU B OE1 1 
ATOM   3217 O  OE2 . GLU B 2 99  ? -9.09   -2.59   -1.393  1   36.46  ? 269 GLU B OE2 1 
ATOM   3218 N  N   . ILE B 2 100 ? -5.596  -6.936  0.694   1   38.84  ? 270 ILE B N   1 
ATOM   3219 C  CA  . ILE B 2 100 ? -4.35   -7.627  0.973   1   38.4   ? 270 ILE B CA  1 
ATOM   3220 C  C   . ILE B 2 100 ? -3.418  -6.656  1.68    1   42.33  ? 270 ILE B C   1 
ATOM   3221 O  O   . ILE B 2 100 ? -2.927  -6.957  2.769   1   41.54  ? 270 ILE B O   1 
ATOM   3222 C  CB  . ILE B 2 100 ? -3.707  -8.188  -0.308  1   37.76  ? 270 ILE B CB  1 
ATOM   3223 C  CG1 . ILE B 2 100 ? -4.633  -9.211  -0.979  1   37.28  ? 270 ILE B CG1 1 
ATOM   3224 C  CG2 . ILE B 2 100 ? -2.325  -8.78   -0.004  1   35.18  ? 270 ILE B CG2 1 
ATOM   3225 C  CD1 . ILE B 2 100 ? -4.195  -9.625  -2.376  1   39.47  ? 270 ILE B CD1 1 
ATOM   3226 N  N   . TYR B 2 101 ? -3.226  -5.489  1.038   1   45.79  ? 271 TYR B N   1 
ATOM   3227 C  CA  . TYR B 2 101 ? -2.395  -4.416  1.562   1   46.04  ? 271 TYR B CA  1 
ATOM   3228 C  C   . TYR B 2 101 ? -3.226  -3.15   1.751   1   44.03  ? 271 TYR B C   1 
ATOM   3229 O  O   . TYR B 2 101 ? -3.298  -2.312  0.857   1   45.71  ? 271 TYR B O   1 
ATOM   3230 C  CB  . TYR B 2 101 ? -1.219  -4.131  0.633   1   44.9   ? 271 TYR B CB  1 
ATOM   3231 C  CG  . TYR B 2 101 ? -0.427  -5.356  0.216   1   46.42  ? 271 TYR B CG  1 
ATOM   3232 C  CD1 . TYR B 2 101 ? 0.537   -5.908  1.057   1   45.87  ? 271 TYR B CD1 1 
ATOM   3233 C  CD2 . TYR B 2 101 ? -0.629  -5.925  -1.049  1   47.22  ? 271 TYR B CD2 1 
ATOM   3234 C  CE1 . TYR B 2 101 ? 1.265   -7.015  0.65    1   50.6   ? 271 TYR B CE1 1 
ATOM   3235 C  CE2 . TYR B 2 101 ? 0.11    -7.017  -1.473  1   48.45  ? 271 TYR B CE2 1 
ATOM   3236 C  CZ  . TYR B 2 101 ? 1.053   -7.56   -0.615  1   54.24  ? 271 TYR B CZ  1 
ATOM   3237 O  OH  . TYR B 2 101 ? 1.753   -8.655  -1.043  1   69.35  ? 271 TYR B OH  1 
ATOM   3238 N  N   . PRO B 2 102 ? -3.865  -2.977  2.929   1   40.77  ? 272 PRO B N   1 
ATOM   3239 C  CA  . PRO B 2 102 ? -4.539  -1.723  3.262   1   39.27  ? 272 PRO B CA  1 
ATOM   3240 C  C   . PRO B 2 102 ? -3.515  -0.591  3.324   1   41.52  ? 272 PRO B C   1 
ATOM   3241 O  O   . PRO B 2 102 ? -2.357  -0.787  3.706   1   41.34  ? 272 PRO B O   1 
ATOM   3242 C  CB  . PRO B 2 102 ? -5.135  -2.016  4.646   1   36.14  ? 272 PRO B CB  1 
ATOM   3243 C  CG  . PRO B 2 102 ? -4.222  -3.105  5.192   1   36.94  ? 272 PRO B CG  1 
ATOM   3244 C  CD  . PRO B 2 102 ? -3.956  -3.98   3.999   1   37.5   ? 272 PRO B CD  1 
ATOM   3245 N  N   . PRO B 2 103 ? -3.922  0.637   2.942   1   41.68  ? 273 PRO B N   1 
ATOM   3246 C  CA  . PRO B 2 103 ? -3.116  1.83    3.22    1   44.15  ? 273 PRO B CA  1 
ATOM   3247 C  C   . PRO B 2 103 ? -2.904  1.982   4.727   1   46.4   ? 273 PRO B C   1 
ATOM   3248 O  O   . PRO B 2 103 ? -3.717  1.527   5.533   1   48.52  ? 273 PRO B O   1 
ATOM   3249 C  CB  . PRO B 2 103 ? -3.923  3.009   2.631   1   43.64  ? 273 PRO B CB  1 
ATOM   3250 C  CG  . PRO B 2 103 ? -5.111  2.387   1.89    1   42.02  ? 273 PRO B CG  1 
ATOM   3251 C  CD  . PRO B 2 103 ? -5.176  0.911   2.223   1   38.91  ? 273 PRO B CD  1 
ATOM   3252 N  N   . GLU B 2 104 ? -1.82   2.653   5.1     1   49.02  ? 274 GLU B N   1 
ATOM   3253 C  CA  . GLU B 2 104 ? -1.555  2.937   6.5     1   58.24  ? 274 GLU B CA  1 
ATOM   3254 C  C   . GLU B 2 104 ? -2.551  3.975   7.022   1   55.92  ? 274 GLU B C   1 
ATOM   3255 O  O   . GLU B 2 104 ? -3.139  4.742   6.258   1   53.77  ? 274 GLU B O   1 
ATOM   3256 C  CB  . GLU B 2 104 ? -0.115  3.421   6.701   1   66.42  ? 274 GLU B CB  1 
ATOM   3257 C  CG  . GLU B 2 104 ? 0.932   2.315   6.572   1   78.89  ? 274 GLU B CG  1 
ATOM   3258 C  CD  . GLU B 2 104 ? 2.37    2.744   6.289   1   94.53  ? 274 GLU B CD  1 
ATOM   3259 O  OE1 . GLU B 2 104 ? 3.264   1.864   6.231   1   99.71  ? 274 GLU B OE1 1 
ATOM   3260 O  OE2 . GLU B 2 104 ? 2.61    3.961   6.113   1   97.31  ? 274 GLU B OE2 1 
ATOM   3261 N  N   . VAL B 2 105 ? -2.711  4.005   8.35    1   55.09  ? 275 VAL B N   1 
ATOM   3262 C  CA  . VAL B 2 105 ? -3.518  5.026   8.996   1   51.74  ? 275 VAL B CA  1 
ATOM   3263 C  C   . VAL B 2 105 ? -3.04   6.398   8.526   1   53.69  ? 275 VAL B C   1 
ATOM   3264 O  O   . VAL B 2 105 ? -3.871  7.233   8.158   1   54.44  ? 275 VAL B O   1 
ATOM   3265 C  CB  . VAL B 2 105 ? -3.527  4.912   10.531  1   48.89  ? 275 VAL B CB  1 
ATOM   3266 C  CG1 . VAL B 2 105 ? -4.473  5.932   11.15   1   46.45  ? 275 VAL B CG1 1 
ATOM   3267 C  CG2 . VAL B 2 105 ? -3.887  3.491   10.957  1   47.53  ? 275 VAL B CG2 1 
ATOM   3268 N  N   . ALA B 2 106 ? -1.707  6.601   8.529   1   53.28  ? 276 ALA B N   1 
ATOM   3269 C  CA  . ALA B 2 106 ? -1.12   7.88    8.148   1   53.9   ? 276 ALA B CA  1 
ATOM   3270 C  C   . ALA B 2 106 ? -1.601  8.294   6.75    1   54.62  ? 276 ALA B C   1 
ATOM   3271 O  O   . ALA B 2 106 ? -2.015  9.437   6.544   1   54.96  ? 276 ALA B O   1 
ATOM   3272 C  CB  . ALA B 2 106 ? 0.39    7.873   8.3     1   52.76  ? 276 ALA B CB  1 
ATOM   3273 N  N   . GLU B 2 107 ? -1.624  7.347   5.807   1   52.68  ? 277 GLU B N   1 
ATOM   3274 C  CA  . GLU B 2 107 ? -2.173  7.641   4.496   1   55.79  ? 277 GLU B CA  1 
ATOM   3275 C  C   . GLU B 2 107 ? -3.589  8.209   4.636   1   52.54  ? 277 GLU B C   1 
ATOM   3276 O  O   . GLU B 2 107 ? -3.914  9.203   3.989   1   53.18  ? 277 GLU B O   1 
ATOM   3277 C  CB  . GLU B 2 107 ? -2.009  6.463   3.532   1   59.04  ? 277 GLU B CB  1 
ATOM   3278 C  CG  . GLU B 2 107 ? -0.653  6.457   2.827   1   68.54  ? 277 GLU B CG  1 
ATOM   3279 C  CD  . GLU B 2 107 ? 0.034   5.103   2.708   1   80.02  ? 277 GLU B CD  1 
ATOM   3280 O  OE1 . GLU B 2 107 ? -0.561  4.098   2.235   1   78.9   ? 277 GLU B OE1 1 
ATOM   3281 O  OE2 . GLU B 2 107 ? 1.226   5.073   3.097   1   92.19  ? 277 GLU B OE2 1 
ATOM   3282 N  N   . PHE B 2 108 ? -4.418  7.579   5.478   1   48.99  ? 278 PHE B N   1 
ATOM   3283 C  CA  . PHE B 2 108 ? -5.8    7.997   5.641   1   46.76  ? 278 PHE B CA  1 
ATOM   3284 C  C   . PHE B 2 108 ? -5.847  9.402   6.241   1   51.29  ? 278 PHE B C   1 
ATOM   3285 O  O   . PHE B 2 108 ? -6.632  10.226  5.786   1   54.52  ? 278 PHE B O   1 
ATOM   3286 C  CB  . PHE B 2 108 ? -6.649  6.999   6.43    1   45.01  ? 278 PHE B CB  1 
ATOM   3287 C  CG  . PHE B 2 108 ? -7.102  5.794   5.623   1   46.08  ? 278 PHE B CG  1 
ATOM   3288 C  CD1 . PHE B 2 108 ? -8.138  5.918   4.702   1   45.86  ? 278 PHE B CD1 1 
ATOM   3289 C  CD2 . PHE B 2 108 ? -6.485  4.549   5.758   1   46.38  ? 278 PHE B CD2 1 
ATOM   3290 C  CE1 . PHE B 2 108 ? -8.56   4.818   3.961   1   43.63  ? 278 PHE B CE1 1 
ATOM   3291 C  CE2 . PHE B 2 108 ? -6.904  3.45    5.007   1   46.77  ? 278 PHE B CE2 1 
ATOM   3292 C  CZ  . PHE B 2 108 ? -7.947  3.584   4.109   1   44.17  ? 278 PHE B CZ  1 
ATOM   3293 N  N   . VAL B 2 109 ? -4.997  9.688   7.24    1   51.1   ? 279 VAL B N   1 
ATOM   3294 C  CA  . VAL B 2 109 ? -4.919  11.023  7.816   1   50.54  ? 279 VAL B CA  1 
ATOM   3295 C  C   . VAL B 2 109 ? -4.584  12.03   6.719   1   52.64  ? 279 VAL B C   1 
ATOM   3296 O  O   . VAL B 2 109 ? -5.143  13.119  6.672   1   52.73  ? 279 VAL B O   1 
ATOM   3297 C  CB  . VAL B 2 109 ? -3.869  11.085  8.94    1   50.88  ? 279 VAL B CB  1 
ATOM   3298 C  CG1 . VAL B 2 109 ? -3.691  12.497  9.483   1   51.01  ? 279 VAL B CG1 1 
ATOM   3299 C  CG2 . VAL B 2 109 ? -4.168  10.108  10.069  1   51.2   ? 279 VAL B CG2 1 
ATOM   3300 N  N   . TYR B 2 110 ? -3.661  11.681  5.831   1   55.37  ? 280 TYR B N   1 
ATOM   3301 C  CA  . TYR B 2 110 ? -3.197  12.645  4.801   1   59.74  ? 280 TYR B CA  1 
ATOM   3302 C  C   . TYR B 2 110 ? -4.283  12.965  3.786   1   59.79  ? 280 TYR B C   1 
ATOM   3303 O  O   . TYR B 2 110 ? -4.296  14.098  3.283   1   62.26  ? 280 TYR B O   1 
ATOM   3304 C  CB  . TYR B 2 110 ? -1.965  12.023  4.147   1   66.31  ? 280 TYR B CB  1 
ATOM   3305 C  CG  . TYR B 2 110 ? -1.387  12.788  2.967   1   77.82  ? 280 TYR B CG  1 
ATOM   3306 C  CD1 . TYR B 2 110 ? -0.522  13.855  3.164   1   88.44  ? 280 TYR B CD1 1 
ATOM   3307 C  CD2 . TYR B 2 110 ? -1.697  12.436  1.661   1   78.06  ? 280 TYR B CD2 1 
ATOM   3308 C  CE1 . TYR B 2 110 ? 0.013   14.555  2.096   1   95.07  ? 280 TYR B CE1 1 
ATOM   3309 C  CE2 . TYR B 2 110 ? -1.171  13.129  0.584   1   85.53  ? 280 TYR B CE2 1 
ATOM   3310 C  CZ  . TYR B 2 110 ? -0.314  14.191  0.803   1   98.09  ? 280 TYR B CZ  1 
ATOM   3311 O  OH  . TYR B 2 110 ? 0.211   14.879  -0.251  1   104.63 ? 280 TYR B OH  1 
ATOM   3312 N  N   . ILE B 2 111 ? -5.17   12.021  3.484   1   56.88  ? 281 ILE B N   1 
ATOM   3313 C  CA  . ILE B 2 111 ? -6.18   12.266  2.412   1   58.15  ? 281 ILE B CA  1 
ATOM   3314 C  C   . ILE B 2 111 ? -7.288  13.176  2.959   1   59.17  ? 281 ILE B C   1 
ATOM   3315 O  O   . ILE B 2 111 ? -8.136  13.607  2.165   1   56.63  ? 281 ILE B O   1 
ATOM   3316 C  CB  . ILE B 2 111 ? -6.724  10.943  1.85    1   56.1   ? 281 ILE B CB  1 
ATOM   3317 C  CG1 . ILE B 2 111 ? -7.622  10.227  2.846   1   57.26  ? 281 ILE B CG1 1 
ATOM   3318 C  CG2 . ILE B 2 111 ? -5.581  10.053  1.376   1   54.87  ? 281 ILE B CG2 1 
ATOM   3319 C  CD1 . ILE B 2 111 ? -7.76   8.741   2.59    1   61.13  ? 281 ILE B CD1 1 
ATOM   3320 N  N   . THR B 2 112 ? -7.256  13.459  4.257   1   62.47  ? 282 THR B N   1 
ATOM   3321 C  CA  . THR B 2 112 ? -8.225  14.376  4.872   1   66.96  ? 282 THR B CA  1 
ATOM   3322 C  C   . THR B 2 112 ? -7.604  15.754  4.984   1   75.38  ? 282 THR B C   1 
ATOM   3323 O  O   . THR B 2 112 ? -8.056  16.517  5.834   1   75.37  ? 282 THR B O   1 
ATOM   3324 C  CB  . THR B 2 112 ? -8.604  13.835  6.247   1   66.8   ? 282 THR B CB  1 
ATOM   3325 O  OG1 . THR B 2 112 ? -7.462  14.045  7.07    1   69.24  ? 282 THR B OG1 1 
ATOM   3326 C  CG2 . THR B 2 112 ? -8.973  12.364  6.217   1   56.63  ? 282 THR B CG2 1 
ATOM   3327 N  N   . ASP B 2 113 ? -6.462  15.937  4.165   1   81.81  ? 283 ASP B N   1 
ATOM   3328 C  CA  . ASP B 2 113 ? -5.798  17.269  4.164   1   89.22  ? 283 ASP B CA  1 
ATOM   3329 C  C   . ASP B 2 113 ? -5.624  17.742  5.609   1   89.67  ? 283 ASP B C   1 
ATOM   3330 O  O   . ASP B 2 113 ? -6.015  18.887  5.907   1   80.68  ? 283 ASP B O   1 
ATOM   3331 C  CB  . ASP B 2 113 ? -6.555  18.268  3.309   1   95.26  ? 283 ASP B CB  1 
ATOM   3332 C  CG  . ASP B 2 113 ? -5.698  19.3    2.594   1   104.93 ? 283 ASP B CG  1 
ATOM   3333 O  OD1 . ASP B 2 113 ? -4.487  19.362  2.889   1   108.52 ? 283 ASP B OD1 1 
ATOM   3334 O  OD2 . ASP B 2 113 ? -6.25   20.034  1.75    1   111.83 ? 283 ASP B OD2 1 
ATOM   3335 N  N   . ASP B 2 114 ? -5.15   16.953  6.469   1   96.27  ? 284 ASP B N   1 
ATOM   3336 C  CA  . ASP B 2 114 ? -4.904  17.238  7.881   1   104.33 ? 284 ASP B CA  1 
ATOM   3337 C  C   . ASP B 2 114 ? -6.073  17.98   8.537   1   95.13  ? 284 ASP B C   1 
ATOM   3338 O  O   . ASP B 2 114 ? -5.866  18.81   9.423   1   89.81  ? 284 ASP B O   1 
ATOM   3339 C  CB  . ASP B 2 114 ? -3.544  17.885  8.113   1   115.29 ? 284 ASP B CB  1 
ATOM   3340 C  CG  . ASP B 2 114 ? -2.33   16.989  7.908   1   114.48 ? 284 ASP B CG  1 
ATOM   3341 O  OD1 . ASP B 2 114 ? -2.509  15.867  7.382   1   109.03 ? 284 ASP B OD1 1 
ATOM   3342 O  OD2 . ASP B 2 114 ? -1.217  17.425  8.281   1   115.02 ? 284 ASP B OD2 1 
ATOM   3343 N  N   . THR B 2 115 ? -7.3    17.647  8.118   1   87.53  ? 285 THR B N   1 
ATOM   3344 C  CA  . THR B 2 115 ? -8.499  18.143  8.769   1   82.31  ? 285 THR B CA  1 
ATOM   3345 C  C   . THR B 2 115 ? -8.592  17.473  10.137  1   77.54  ? 285 THR B C   1 
ATOM   3346 O  O   . THR B 2 115 ? -8.94   18.126  11.114  1   79.69  ? 285 THR B O   1 
ATOM   3347 C  CB  . THR B 2 115 ? -9.728  17.865  7.899   1   80.55  ? 285 THR B CB  1 
ATOM   3348 O  OG1 . THR B 2 115 ? -9.382  18.423  6.639   1   80.75  ? 285 THR B OG1 1 
ATOM   3349 C  CG2 . THR B 2 115 ? -10.986 18.573  8.367   1   78.56  ? 285 THR B CG2 1 
ATOM   3350 N  N   . TYR B 2 116 ? -8.255  16.173  10.183  1   69.35  ? 286 TYR B N   1 
ATOM   3351 C  CA  . TYR B 2 116 ? -8.31   15.395  11.409  1   61.21  ? 286 TYR B CA  1 
ATOM   3352 C  C   . TYR B 2 116 ? -6.936  14.844  11.782  1   60.63  ? 286 TYR B C   1 
ATOM   3353 O  O   . TYR B 2 116 ? -6.074  14.64   10.924  1   59.78  ? 286 TYR B O   1 
ATOM   3354 C  CB  . TYR B 2 116 ? -9.277  14.225  11.259  1   55.15  ? 286 TYR B CB  1 
ATOM   3355 C  CG  . TYR B 2 116 ? -10.625 14.619  10.674  1   54.37  ? 286 TYR B CG  1 
ATOM   3356 C  CD1 . TYR B 2 116 ? -11.494 15.486  11.349  1   52.78  ? 286 TYR B CD1 1 
ATOM   3357 C  CD2 . TYR B 2 116 ? -11.029 14.104  9.442   1   51.15  ? 286 TYR B CD2 1 
ATOM   3358 C  CE1 . TYR B 2 116 ? -12.729 15.82   10.809  1   52.15  ? 286 TYR B CE1 1 
ATOM   3359 C  CE2 . TYR B 2 116 ? -12.257 14.438  8.891   1   50.97  ? 286 TYR B CE2 1 
ATOM   3360 C  CZ  . TYR B 2 116 ? -13.106 15.3    9.573   1   52.55  ? 286 TYR B CZ  1 
ATOM   3361 O  OH  . TYR B 2 116 ? -14.308 15.594  8.978   1   51.71  ? 286 TYR B OH  1 
ATOM   3362 N  N   . THR B 2 117 ? -6.766  14.608  13.089  1   57.34  ? 287 THR B N   1 
ATOM   3363 C  CA  . THR B 2 117 ? -5.57   13.989  13.624  1   55.37  ? 287 THR B CA  1 
ATOM   3364 C  C   . THR B 2 117 ? -5.69   12.477  13.498  1   53.88  ? 287 THR B C   1 
ATOM   3365 O  O   . THR B 2 117 ? -6.774  11.925  13.27   1   51.74  ? 287 THR B O   1 
ATOM   3366 C  CB  . THR B 2 117 ? -5.338  14.386  15.083  1   57.64  ? 287 THR B CB  1 
ATOM   3367 O  OG1 . THR B 2 117 ? -6.215  13.58   15.866  1   55.1   ? 287 THR B OG1 1 
ATOM   3368 C  CG2 . THR B 2 117 ? -5.455  15.881  15.343  1   57.6   ? 287 THR B CG2 1 
ATOM   3369 N  N   . LYS B 2 118 ? -4.542  11.814  13.669  1   55.06  ? 288 LYS B N   1 
ATOM   3370 C  CA  . LYS B 2 118 ? -4.47   10.365  13.625  1   52.94  ? 288 LYS B CA  1 
ATOM   3371 C  C   . LYS B 2 118 ? -5.222  9.798   14.829  1   52.26  ? 288 LYS B C   1 
ATOM   3372 O  O   . LYS B 2 118 ? -5.895  8.782   14.698  1   48.38  ? 288 LYS B O   1 
ATOM   3373 C  CB  . LYS B 2 118 ? -2.999  9.96    13.513  1   54.11  ? 288 LYS B CB  1 
ATOM   3374 C  CG  . LYS B 2 118 ? -2.73   8.482   13.395  1   54.52  ? 288 LYS B CG  1 
ATOM   3375 C  CD  . LYS B 2 118 ? -1.273  8.098   13.621  1   57.25  ? 288 LYS B CD  1 
ATOM   3376 C  CE  . LYS B 2 118 ? -1.32   6.746   14.287  1   62.04  ? 288 LYS B CE  1 
ATOM   3377 N  NZ  . LYS B 2 118 ? -0.22   5.797   14.042  1   66.47  ? 288 LYS B NZ  1 
ATOM   3378 N  N   . LYS B 2 119 ? -5.141  10.485  15.981  1   55.38  ? 289 LYS B N   1 
ATOM   3379 C  CA  . LYS B 2 119 ? -5.863  10.088  17.177  1   58.39  ? 289 LYS B CA  1 
ATOM   3380 C  C   . LYS B 2 119 ? -7.368  10.126  16.929  1   59.42  ? 289 LYS B C   1 
ATOM   3381 O  O   . LYS B 2 119 ? -8.109  9.295   17.444  1   61.44  ? 289 LYS B O   1 
ATOM   3382 C  CB  . LYS B 2 119 ? -5.555  11.032  18.331  1   63.08  ? 289 LYS B CB  1 
ATOM   3383 C  CG  . LYS B 2 119 ? -5.986  10.476  19.663  1   72.66  ? 289 LYS B CG  1 
ATOM   3384 C  CD  . LYS B 2 119 ? -5.928  11.53   20.767  1   85.07  ? 289 LYS B CD  1 
ATOM   3385 C  CE  . LYS B 2 119 ? -6.228  10.984  22.134  1   87.68  ? 289 LYS B CE  1 
ATOM   3386 N  NZ  . LYS B 2 119 ? -6.151  12.049  23.135  1   87.15  ? 289 LYS B NZ  1 
ATOM   3387 N  N   . GLN B 2 120 ? -7.82   11.111  16.149  1   57.82  ? 290 GLN B N   1 
ATOM   3388 C  CA  . GLN B 2 120 ? -9.234  11.237  15.825  1   54.72  ? 290 GLN B CA  1 
ATOM   3389 C  C   . GLN B 2 120 ? -9.726  10.056  14.975  1   51.87  ? 290 GLN B C   1 
ATOM   3390 O  O   . GLN B 2 120 ? -10.831 9.554   15.204  1   50.96  ? 290 GLN B O   1 
ATOM   3391 C  CB  . GLN B 2 120 ? -9.529  12.59   15.181  1   52.73  ? 290 GLN B CB  1 
ATOM   3392 C  CG  . GLN B 2 120 ? -9.604  13.772  16.144  1   54.45  ? 290 GLN B CG  1 
ATOM   3393 C  CD  . GLN B 2 120 ? -10.022 15.031  15.415  1   55.41  ? 290 GLN B CD  1 
ATOM   3394 O  OE1 . GLN B 2 120 ? -9.412  15.431  14.418  1   55.82  ? 290 GLN B OE1 1 
ATOM   3395 N  NE2 . GLN B 2 120 ? -11.11  15.638  15.856  1   56.35  ? 290 GLN B NE2 1 
ATOM   3396 N  N   . VAL B 2 121 ? -8.926  9.646   13.975  1   49.05  ? 291 VAL B N   1 
ATOM   3397 C  CA  . VAL B 2 121 ? -9.287  8.582   13.051  1   42.51  ? 291 VAL B CA  1 
ATOM   3398 C  C   . VAL B 2 121 ? -9.367  7.269   13.819  1   42.73  ? 291 VAL B C   1 
ATOM   3399 O  O   . VAL B 2 121 ? -10.313 6.507   13.642  1   42.01  ? 291 VAL B O   1 
ATOM   3400 C  CB  . VAL B 2 121 ? -8.34   8.44    11.843  1   41.23  ? 291 VAL B CB  1 
ATOM   3401 C  CG1 . VAL B 2 121 ? -8.662  7.216   10.981  1   37.8   ? 291 VAL B CG1 1 
ATOM   3402 C  CG2 . VAL B 2 121 ? -8.311  9.704   11      1   41.78  ? 291 VAL B CG2 1 
ATOM   3403 N  N   . LEU B 2 122 ? -8.375  7.018   14.676  1   44.07  ? 292 LEU B N   1 
ATOM   3404 C  CA  . LEU B 2 122 ? -8.338  5.733   15.422  1   43.58  ? 292 LEU B CA  1 
ATOM   3405 C  C   . LEU B 2 122 ? -9.498  5.692   16.43   1   43.87  ? 292 LEU B C   1 
ATOM   3406 O  O   . LEU B 2 122 ? -10.066 4.597   16.634  1   45.18  ? 292 LEU B O   1 
ATOM   3407 C  CB  . LEU B 2 122 ? -6.975  5.578   16.093  1   45.33  ? 292 LEU B CB  1 
ATOM   3408 C  CG  . LEU B 2 122 ? -5.809  5.307   15.137  1   45.96  ? 292 LEU B CG  1 
ATOM   3409 C  CD1 . LEU B 2 122 ? -4.597  4.753   15.865  1   45.38  ? 292 LEU B CD1 1 
ATOM   3410 C  CD2 . LEU B 2 122 ? -6.25   4.365   14.029  1   43.57  ? 292 LEU B CD2 1 
ATOM   3411 N  N   . ARG B 2 123 ? -9.836  6.836   17.032  1   45.34  ? 293 ARG B N   1 
ATOM   3412 C  CA  . ARG B 2 123 ? -10.992 6.885   17.964  1   46.03  ? 293 ARG B CA  1 
ATOM   3413 C  C   . ARG B 2 123 ? -12.271 6.59    17.17   1   45     ? 293 ARG B C   1 
ATOM   3414 O  O   . ARG B 2 123 ? -13.043 5.704   17.593  1   45.08  ? 293 ARG B O   1 
ATOM   3415 C  CB  . ARG B 2 123 ? -11.084 8.259   18.635  1   48.9   ? 293 ARG B CB  1 
ATOM   3416 C  CG  . ARG B 2 123 ? -10.198 8.429   19.859  1   54.48  ? 293 ARG B CG  1 
ATOM   3417 C  CD  . ARG B 2 123 ? -10.4   9.802   20.475  1   67.5   ? 293 ARG B CD  1 
ATOM   3418 N  NE  . ARG B 2 123 ? -11.755 9.949   21.016  1   83.46  ? 293 ARG B NE  1 
ATOM   3419 C  CZ  . ARG B 2 123 ? -12.239 11.072  21.528  1   83.91  ? 293 ARG B CZ  1 
ATOM   3420 N  NH1 . ARG B 2 123 ? -12.621 11.109  22.791  1   82.96  ? 293 ARG B NH1 1 
ATOM   3421 N  NH2 . ARG B 2 123 ? -12.339 12.15   20.772  1   74.19  ? 293 ARG B NH2 1 
ATOM   3422 N  N   . MET B 2 124 ? -12.484 7.311   16.067  1   44.07  ? 294 MET B N   1 
ATOM   3423 C  CA  . MET B 2 124 ? -13.649 7.073   15.23   1   42.98  ? 294 MET B CA  1 
ATOM   3424 C  C   . MET B 2 124 ? -13.716 5.604   14.81   1   42.71  ? 294 MET B C   1 
ATOM   3425 O  O   . MET B 2 124 ? -14.781 4.997   14.854  1   43.79  ? 294 MET B O   1 
ATOM   3426 C  CB  . MET B 2 124 ? -13.606 7.957   13.991  1   42.85  ? 294 MET B CB  1 
ATOM   3427 C  CG  . MET B 2 124 ? -14.874 7.951   13.154  1   41.77  ? 294 MET B CG  1 
ATOM   3428 S  SD  . MET B 2 124 ? -16.414 8.219   14.043  1   39.46  ? 294 MET B SD  1 
ATOM   3429 C  CE  . MET B 2 124 ? -16.595 9.993   13.897  1   40.37  ? 294 MET B CE  1 
ATOM   3430 N  N   . GLU B 2 125 ? -12.557 5.014   14.489  1   41.7   ? 295 GLU B N   1 
ATOM   3431 C  CA  . GLU B 2 125 ? -12.494 3.626   14.083  1   40.65  ? 295 GLU B CA  1 
ATOM   3432 C  C   . GLU B 2 125 ? -13.15  2.775   15.164  1   41.24  ? 295 GLU B C   1 
ATOM   3433 O  O   . GLU B 2 125 ? -13.97  1.919   14.856  1   40.57  ? 295 GLU B O   1 
ATOM   3434 C  CB  . GLU B 2 125 ? -11.05  3.207   13.808  1   41.15  ? 295 GLU B CB  1 
ATOM   3435 C  CG  . GLU B 2 125 ? -10.935 1.749   13.379  1   42.1   ? 295 GLU B CG  1 
ATOM   3436 C  CD  . GLU B 2 125 ? -9.544  1.147   13.305  1   43.36  ? 295 GLU B CD  1 
ATOM   3437 O  OE1 . GLU B 2 125 ? -8.859  1.054   14.341  1   46.59  ? 295 GLU B OE1 1 
ATOM   3438 O  OE2 . GLU B 2 125 ? -9.143  0.756   12.19   1   44.58  ? 295 GLU B OE2 1 
ATOM   3439 N  N   . HIS B 2 126 ? -12.788 3.035   16.423  1   43.58  ? 296 HIS B N   1 
ATOM   3440 C  CA  . HIS B 2 126 ? -13.272 2.252   17.541  1   47.5   ? 296 HIS B CA  1 
ATOM   3441 C  C   . HIS B 2 126 ? -14.771 2.47    17.707  1   47.9   ? 296 HIS B C   1 
ATOM   3442 O  O   . HIS B 2 126 ? -15.503 1.511   17.94   1   48.43  ? 296 HIS B O   1 
ATOM   3443 C  CB  . HIS B 2 126 ? -12.557 2.643   18.838  1   54.8   ? 296 HIS B CB  1 
ATOM   3444 C  CG  . HIS B 2 126 ? -12.423 1.487   19.76   1   65.61  ? 296 HIS B CG  1 
ATOM   3445 N  ND1 . HIS B 2 126 ? -12.297 1.568   21.129  1   79.68  ? 296 HIS B ND1 1 
ATOM   3446 C  CD2 . HIS B 2 126 ? -12.398 0.19    19.462  1   73.93  ? 296 HIS B CD2 1 
ATOM   3447 C  CE1 . HIS B 2 126 ? -12.194 0.348   21.636  1   87.56  ? 296 HIS B CE1 1 
ATOM   3448 N  NE2 . HIS B 2 126 ? -12.245 -0.506  20.63   1   86.36  ? 296 HIS B NE2 1 
ATOM   3449 N  N   . LEU B 2 127 ? -15.202 3.742   17.624  1   44.78  ? 297 LEU B N   1 
ATOM   3450 C  CA  . LEU B 2 127 ? -16.599 4.13    17.715  1   42.11  ? 297 LEU B CA  1 
ATOM   3451 C  C   . LEU B 2 127 ? -17.415 3.373   16.671  1   41.22  ? 297 LEU B C   1 
ATOM   3452 O  O   . LEU B 2 127 ? -18.464 2.852   17.014  1   43.02  ? 297 LEU B O   1 
ATOM   3453 C  CB  . LEU B 2 127 ? -16.816 5.636   17.585  1   40.84  ? 297 LEU B CB  1 
ATOM   3454 C  CG  . LEU B 2 127 ? -18.246 6.112   17.885  1   40.75  ? 297 LEU B CG  1 
ATOM   3455 C  CD1 . LEU B 2 127 ? -18.674 5.724   19.301  1   41.75  ? 297 LEU B CD1 1 
ATOM   3456 C  CD2 . LEU B 2 127 ? -18.418 7.603   17.663  1   41.31  ? 297 LEU B CD2 1 
ATOM   3457 N  N   . VAL B 2 128 ? -16.944 3.349   15.413  1   38.06  ? 298 VAL B N   1 
ATOM   3458 C  CA  . VAL B 2 128 ? -17.631 2.688   14.319  1   36.26  ? 298 VAL B CA  1 
ATOM   3459 C  C   . VAL B 2 128 ? -17.734 1.191   14.618  1   38.66  ? 298 VAL B C   1 
ATOM   3460 O  O   . VAL B 2 128 ? -18.771 0.586   14.348  1   38.37  ? 298 VAL B O   1 
ATOM   3461 C  CB  . VAL B 2 128 ? -17.013 2.933   12.925  1   33.95  ? 298 VAL B CB  1 
ATOM   3462 C  CG1 . VAL B 2 128 ? -17.564 1.976   11.877  1   30.7   ? 298 VAL B CG1 1 
ATOM   3463 C  CG2 . VAL B 2 128 ? -17.178 4.374   12.44   1   33.75  ? 298 VAL B CG2 1 
ATOM   3464 N  N   . LEU B 2 129 ? -16.686 0.607   15.186  1   38.2   ? 299 LEU B N   1 
ATOM   3465 C  CA  . LEU B 2 129 ? -16.697 -0.847  15.46   1   38.11  ? 299 LEU B CA  1 
ATOM   3466 C  C   . LEU B 2 129 ? -17.714 -1.157  16.557  1   38.78  ? 299 LEU B C   1 
ATOM   3467 O  O   . LEU B 2 129 ? -18.356 -2.21   16.481  1   39.68  ? 299 LEU B O   1 
ATOM   3468 C  CB  . LEU B 2 129 ? -15.293 -1.292  15.842  1   41     ? 299 LEU B CB  1 
ATOM   3469 C  CG  . LEU B 2 129 ? -14.349 -1.58   14.676  1   41.51  ? 299 LEU B CG  1 
ATOM   3470 C  CD1 . LEU B 2 129 ? -12.969 -1.903  15.204  1   39.22  ? 299 LEU B CD1 1 
ATOM   3471 C  CD2 . LEU B 2 129 ? -14.907 -2.723  13.855  1   39.33  ? 299 LEU B CD2 1 
ATOM   3472 N  N   . LYS B 2 130 ? -17.86  -0.251  17.517  1   41.75  ? 300 LYS B N   1 
ATOM   3473 C  CA  . LYS B 2 130 ? -18.824 -0.44   18.628  1   48.62  ? 300 LYS B CA  1 
ATOM   3474 C  C   . LYS B 2 130 ? -20.259 -0.272  18.113  1   43.63  ? 300 LYS B C   1 
ATOM   3475 O  O   . LYS B 2 130 ? -21.126 -1.057  18.511  1   44.11  ? 300 LYS B O   1 
ATOM   3476 C  CB  . LYS B 2 130 ? -18.458 0.55    19.737  1   56.84  ? 300 LYS B CB  1 
ATOM   3477 C  CG  . LYS B 2 130 ? -19.45  0.66    20.882  1   79.42  ? 300 LYS B CG  1 
ATOM   3478 C  CD  . LYS B 2 130 ? -19.95  2.079   21.118  1   109.3  ? 300 LYS B CD  1 
ATOM   3479 C  CE  . LYS B 2 130 ? -21.287 2.112   21.785  1   120.01 ? 300 LYS B CE  1 
ATOM   3480 N  NZ  . LYS B 2 130 ? -22.321 1.487   20.957  1   121.27 ? 300 LYS B NZ  1 
ATOM   3481 N  N   . VAL B 2 131 ? -20.485 0.712   17.254  1   42.25  ? 301 VAL B N   1 
ATOM   3482 C  CA  . VAL B 2 131 ? -21.856 0.982   16.74   1   43.96  ? 301 VAL B CA  1 
ATOM   3483 C  C   . VAL B 2 131 ? -22.292 -0.176  15.835  1   42.83  ? 301 VAL B C   1 
ATOM   3484 O  O   . VAL B 2 131 ? -23.484 -0.511  15.834  1   44.01  ? 301 VAL B O   1 
ATOM   3485 C  CB  . VAL B 2 131 ? -21.875 2.349   16.029  1   42.75  ? 301 VAL B CB  1 
ATOM   3486 C  CG1 . VAL B 2 131 ? -23.076 2.524   15.109  1   39.08  ? 301 VAL B CG1 1 
ATOM   3487 C  CG2 . VAL B 2 131 ? -21.782 3.494   17.025  1   42.31  ? 301 VAL B CG2 1 
ATOM   3488 N  N   . LEU B 2 132 ? -21.348 -0.795  15.135  1   41.35  ? 302 LEU B N   1 
ATOM   3489 C  CA  . LEU B 2 132 ? -21.726 -1.842  14.194  1   38.19  ? 302 LEU B CA  1 
ATOM   3490 C  C   . LEU B 2 132 ? -21.622 -3.207  14.88   1   38.56  ? 302 LEU B C   1 
ATOM   3491 O  O   . LEU B 2 132 ? -21.862 -4.244  14.245  1   39.36  ? 302 LEU B O   1 
ATOM   3492 C  CB  . LEU B 2 132 ? -20.814 -1.751  12.968  1   36.18  ? 302 LEU B CB  1 
ATOM   3493 C  CG  . LEU B 2 132 ? -20.882 -0.436  12.173  1   35.73  ? 302 LEU B CG  1 
ATOM   3494 C  CD1 . LEU B 2 132 ? -20.031 -0.462  10.901  1   32.96  ? 302 LEU B CD1 1 
ATOM   3495 C  CD2 . LEU B 2 132 ? -22.286 0.04    11.842  1   35.1   ? 302 LEU B CD2 1 
ATOM   3496 N  N   . ALA B 2 133 ? -21.255 -3.186  16.172  1   38.52  ? 303 ALA B N   1 
ATOM   3497 C  CA  . ALA B 2 133 ? -20.961 -4.379  16.958  1   38.5   ? 303 ALA B CA  1 
ATOM   3498 C  C   . ALA B 2 133 ? -20.063 -5.327  16.157  1   36.73  ? 303 ALA B C   1 
ATOM   3499 O  O   . ALA B 2 133 ? -20.239 -6.537  16.199  1   35.4   ? 303 ALA B O   1 
ATOM   3500 C  CB  . ALA B 2 133 ? -22.237 -5.046  17.442  1   34.49  ? 303 ALA B CB  1 
ATOM   3501 N  N   . PHE B 2 134 ? -19.116 -4.737  15.413  1   37.44  ? 304 PHE B N   1 
ATOM   3502 C  CA  . PHE B 2 134 ? -18.172 -5.449  14.578  1   38.63  ? 304 PHE B CA  1 
ATOM   3503 C  C   . PHE B 2 134 ? -18.849 -6.25   13.461  1   40.22  ? 304 PHE B C   1 
ATOM   3504 O  O   . PHE B 2 134 ? -18.211 -7.178  12.963  1   43.39  ? 304 PHE B O   1 
ATOM   3505 C  CB  . PHE B 2 134 ? -17.385 -6.477  15.397  1   40.28  ? 304 PHE B CB  1 
ATOM   3506 C  CG  . PHE B 2 134 ? -16.15  -5.943  16.1    1   41.52  ? 304 PHE B CG  1 
ATOM   3507 C  CD1 . PHE B 2 134 ? -16.253 -5.324  17.341  1   44.33  ? 304 PHE B CD1 1 
ATOM   3508 C  CD2 . PHE B 2 134 ? -14.901 -6.072  15.516  1   42.67  ? 304 PHE B CD2 1 
ATOM   3509 C  CE1 . PHE B 2 134 ? -15.126 -4.809  17.975  1   46.23  ? 304 PHE B CE1 1 
ATOM   3510 C  CE2 . PHE B 2 134 ? -13.772 -5.586  16.163  1   44.82  ? 304 PHE B CE2 1 
ATOM   3511 C  CZ  . PHE B 2 134 ? -13.889 -4.943  17.378  1   45.28  ? 304 PHE B CZ  1 
ATOM   3512 N  N   . ASP B 2 135 ? -20.098 -5.941  13.058  1   40.98  ? 305 ASP B N   1 
ATOM   3513 C  CA  . ASP B 2 135 ? -20.694 -6.72   11.966  1   42.85  ? 305 ASP B CA  1 
ATOM   3514 C  C   . ASP B 2 135 ? -20.212 -6.182  10.624  1   41.98  ? 305 ASP B C   1 
ATOM   3515 O  O   . ASP B 2 135 ? -20.921 -5.392  10.003  1   44.9   ? 305 ASP B O   1 
ATOM   3516 C  CB  . ASP B 2 135 ? -22.202 -6.908  12.049  1   42.35  ? 305 ASP B CB  1 
ATOM   3517 C  CG  . ASP B 2 135 ? -22.698 -7.614  13.312  1   53.82  ? 305 ASP B CG  1 
ATOM   3518 O  OD1 . ASP B 2 135 ? -21.937 -8.402  13.941  1   58.69  ? 305 ASP B OD1 1 
ATOM   3519 O  OD2 . ASP B 2 135 ? -23.844 -7.354  13.703  1   59.47  ? 305 ASP B OD2 1 
ATOM   3520 N  N   . LEU B 2 136 ? -19.007 -6.605  10.205  1   35.28  ? 306 LEU B N   1 
ATOM   3521 C  CA  . LEU B 2 136 ? -18.33  -5.953  9.089   1   36.5   ? 306 LEU B CA  1 
ATOM   3522 C  C   . LEU B 2 136 ? -18.457 -6.762  7.79    1   33.24  ? 306 LEU B C   1 
ATOM   3523 O  O   . LEU B 2 136 ? -18.163 -6.266  6.706   1   29.64  ? 306 LEU B O   1 
ATOM   3524 C  CB  . LEU B 2 136 ? -16.873 -5.621  9.437   1   38.86  ? 306 LEU B CB  1 
ATOM   3525 C  CG  . LEU B 2 136 ? -16.635 -4.542  10.507  1   41.46  ? 306 LEU B CG  1 
ATOM   3526 C  CD1 . LEU B 2 136 ? -15.192 -4.11   10.357  1   43.37  ? 306 LEU B CD1 1 
ATOM   3527 C  CD2 . LEU B 2 136 ? -17.544 -3.332  10.448  1   37.48  ? 306 LEU B CD2 1 
ATOM   3528 N  N   . ALA B 2 137 ? -18.915 -8.015  7.89    1   32.16  ? 307 ALA B N   1 
ATOM   3529 C  CA  . ALA B 2 137 ? -18.978 -8.862  6.712   1   30.22  ? 307 ALA B CA  1 
ATOM   3530 C  C   . ALA B 2 137 ? -20.319 -8.663  6.007   1   28.19  ? 307 ALA B C   1 
ATOM   3531 O  O   . ALA B 2 137 ? -21.105 -9.572  5.865   1   30.2   ? 307 ALA B O   1 
ATOM   3532 C  CB  . ALA B 2 137 ? -18.687 -10.297 7.1     1   30.07  ? 307 ALA B CB  1 
ATOM   3533 N  N   . ALA B 2 138 ? -20.595 -7.439  5.586   1   28.78  ? 308 ALA B N   1 
ATOM   3534 C  CA  . ALA B 2 138 ? -21.876 -7.11   4.994   1   31.42  ? 308 ALA B CA  1 
ATOM   3535 C  C   . ALA B 2 138 ? -21.858 -7.447  3.511   1   33.43  ? 308 ALA B C   1 
ATOM   3536 O  O   . ALA B 2 138 ? -20.846 -7.257  2.847   1   34.56  ? 308 ALA B O   1 
ATOM   3537 C  CB  . ALA B 2 138 ? -22.095 -5.636  5.169   1   32.54  ? 308 ALA B CB  1 
ATOM   3538 N  N   . PRO B 2 139 ? -22.977 -7.961  2.953   1   35.43  ? 309 PRO B N   1 
ATOM   3539 C  CA  . PRO B 2 139 ? -23.089 -8.202  1.507   1   34.04  ? 309 PRO B CA  1 
ATOM   3540 C  C   . PRO B 2 139 ? -23.146 -6.897  0.726   1   33.58  ? 309 PRO B C   1 
ATOM   3541 O  O   . PRO B 2 139 ? -23.733 -5.921  1.196   1   33.06  ? 309 PRO B O   1 
ATOM   3542 C  CB  . PRO B 2 139 ? -24.418 -8.972  1.374   1   36.04  ? 309 PRO B CB  1 
ATOM   3543 C  CG  . PRO B 2 139 ? -24.725 -9.44   2.783   1   36.18  ? 309 PRO B CG  1 
ATOM   3544 C  CD  . PRO B 2 139 ? -24.168 -8.38   3.711   1   35.02  ? 309 PRO B CD  1 
ATOM   3545 N  N   . THR B 2 140 ? -22.538 -6.9    -0.467  1   34.45  ? 310 THR B N   1 
ATOM   3546 C  CA  . THR B 2 140 ? -22.462 -5.717  -1.316  1   32.56  ? 310 THR B CA  1 
ATOM   3547 C  C   . THR B 2 140 ? -23.157 -5.991  -2.65   1   35.96  ? 310 THR B C   1 
ATOM   3548 O  O   . THR B 2 140 ? -23.514 -7.142  -2.972  1   36.01  ? 310 THR B O   1 
ATOM   3549 C  CB  . THR B 2 140 ? -21.007 -5.285  -1.475  1   33.6   ? 310 THR B CB  1 
ATOM   3550 O  OG1 . THR B 2 140 ? -20.312 -6.375  -2.094  1   36.94  ? 310 THR B OG1 1 
ATOM   3551 C  CG2 . THR B 2 140 ? -20.375 -4.912  -0.143  1   31.18  ? 310 THR B CG2 1 
ATOM   3552 N  N   . ILE B 2 141 ? -23.4   -4.905  -3.403  1   34.19  ? 311 ILE B N   1 
ATOM   3553 C  CA  . ILE B 2 141 ? -23.922 -5.063  -4.741  1   33.06  ? 311 ILE B CA  1 
ATOM   3554 C  C   . ILE B 2 141 ? -22.969 -5.959  -5.532  1   38.51  ? 311 ILE B C   1 
ATOM   3555 O  O   . ILE B 2 141 ? -23.426 -6.785  -6.341  1   40.72  ? 311 ILE B O   1 
ATOM   3556 C  CB  . ILE B 2 141 ? -24.106 -3.693  -5.39   1   31.78  ? 311 ILE B CB  1 
ATOM   3557 C  CG1 . ILE B 2 141 ? -25.326 -3.004  -4.807  1   29.86  ? 311 ILE B CG1 1 
ATOM   3558 C  CG2 . ILE B 2 141 ? -24.221 -3.817  -6.908  1   29.88  ? 311 ILE B CG2 1 
ATOM   3559 C  CD1 . ILE B 2 141 ? -25.257 -1.496  -4.932  1   27.62  ? 311 ILE B CD1 1 
ATOM   3560 N  N   . ASN B 2 142 ? -21.66  -5.824  -5.239  1   37.43  ? 312 ASN B N   1 
ATOM   3561 C  CA  . ASN B 2 142 ? -20.627 -6.589  -5.919  1   41.63  ? 312 ASN B CA  1 
ATOM   3562 C  C   . ASN B 2 142 ? -20.8   -8.093  -5.729  1   40.78  ? 312 ASN B C   1 
ATOM   3563 O  O   . ASN B 2 142 ? -20.675 -8.861  -6.707  1   39.99  ? 312 ASN B O   1 
ATOM   3564 C  CB  . ASN B 2 142 ? -19.219 -6.116  -5.587  1   46.35  ? 312 ASN B CB  1 
ATOM   3565 C  CG  . ASN B 2 142 ? -18.801 -5.08   -6.594  1   57.99  ? 312 ASN B CG  1 
ATOM   3566 O  OD1 . ASN B 2 142 ? -19.544 -4.112  -6.852  1   63.65  ? 312 ASN B OD1 1 
ATOM   3567 N  ND2 . ASN B 2 142 ? -17.652 -5.316  -7.206  1   62.13  ? 312 ASN B ND2 1 
ATOM   3568 N  N   . GLN B 2 143 ? -21.065 -8.488  -4.472  1   33.91  ? 313 GLN B N   1 
ATOM   3569 C  CA  . GLN B 2 143 ? -21.055 -9.901  -4.141  1   33.04  ? 313 GLN B CA  1 
ATOM   3570 C  C   . GLN B 2 143 ? -22.156 -10.599 -4.924  1   31.6   ? 313 GLN B C   1 
ATOM   3571 O  O   . GLN B 2 143 ? -22.017 -11.769 -5.288  1   33.56  ? 313 GLN B O   1 
ATOM   3572 C  CB  . GLN B 2 143 ? -21.121 -10.114 -2.636  1   30.98  ? 313 GLN B CB  1 
ATOM   3573 C  CG  . GLN B 2 143 ? -19.81  -9.786  -1.93   1   31.11  ? 313 GLN B CG  1 
ATOM   3574 C  CD  . GLN B 2 143 ? -19.935 -9.782  -0.419  1   33.82  ? 313 GLN B CD  1 
ATOM   3575 O  OE1 . GLN B 2 143 ? -20.324 -10.782 0.2     1   35.84  ? 313 GLN B OE1 1 
ATOM   3576 N  NE2 . GLN B 2 143 ? -19.658 -8.635  0.194   1   34.79  ? 313 GLN B NE2 1 
ATOM   3577 N  N   . PHE B 2 144 ? -23.231 -9.85   -5.186  1   31.32  ? 314 PHE B N   1 
ATOM   3578 C  CA  . PHE B 2 144 ? -24.346 -10.354 -5.968  1   32.71  ? 314 PHE B CA  1 
ATOM   3579 C  C   . PHE B 2 144 ? -23.968 -10.311 -7.451  1   34.99  ? 314 PHE B C   1 
ATOM   3580 O  O   . PHE B 2 144 ? -24.118 -11.325 -8.146  1   36.05  ? 314 PHE B O   1 
ATOM   3581 C  CB  . PHE B 2 144 ? -25.67  -9.694  -5.565  1   32.26  ? 314 PHE B CB  1 
ATOM   3582 C  CG  . PHE B 2 144 ? -26.242 -10.176 -4.233  1   33.05  ? 314 PHE B CG  1 
ATOM   3583 C  CD1 . PHE B 2 144 ? -26.795 -11.46  -4.104  1   31.35  ? 314 PHE B CD1 1 
ATOM   3584 C  CD2 . PHE B 2 144 ? -26.235 -9.339  -3.107  1   30.67  ? 314 PHE B CD2 1 
ATOM   3585 C  CE1 . PHE B 2 144 ? -27.327 -11.884 -2.879  1   32.16  ? 314 PHE B CE1 1 
ATOM   3586 C  CE2 . PHE B 2 144 ? -26.742 -9.784  -1.881  1   31.48  ? 314 PHE B CE2 1 
ATOM   3587 C  CZ  . PHE B 2 144 ? -27.304 -11.046 -1.773  1   31.3   ? 314 PHE B CZ  1 
ATOM   3588 N  N   . LEU B 2 145 ? -23.445 -9.156  -7.901  1   33.29  ? 315 LEU B N   1 
ATOM   3589 C  CA  . LEU B 2 145 ? -23.104 -8.925  -9.3    1   34.9   ? 315 LEU B CA  1 
ATOM   3590 C  C   . LEU B 2 145 ? -22.223 -10.053 -9.839  1   35.9   ? 315 LEU B C   1 
ATOM   3591 O  O   . LEU B 2 145 ? -22.517 -10.625 -10.905 1   35.96  ? 315 LEU B O   1 
ATOM   3592 C  CB  . LEU B 2 145 ? -22.42  -7.576  -9.497  1   35.56  ? 315 LEU B CB  1 
ATOM   3593 C  CG  . LEU B 2 145 ? -23.304 -6.349  -9.734  1   33.98  ? 315 LEU B CG  1 
ATOM   3594 C  CD1 . LEU B 2 145 ? -22.392 -5.147  -9.892  1   32.04  ? 315 LEU B CD1 1 
ATOM   3595 C  CD2 . LEU B 2 145 ? -24.192 -6.504  -10.956 1   36.63  ? 315 LEU B CD2 1 
ATOM   3596 N  N   . THR B 2 146 ? -21.14  -10.346 -9.095  1   33.83  ? 316 THR B N   1 
ATOM   3597 C  CA  . THR B 2 146 ? -20.138 -11.298 -9.564  1   35.1   ? 316 THR B CA  1 
ATOM   3598 C  C   . THR B 2 146 ? -20.81  -12.661 -9.733  1   35.48  ? 316 THR B C   1 
ATOM   3599 O  O   . THR B 2 146 ? -20.435 -13.433 -10.621 1   36.07  ? 316 THR B O   1 
ATOM   3600 C  CB  . THR B 2 146 ? -18.892 -11.388 -8.662  1   35.03  ? 316 THR B CB  1 
ATOM   3601 O  OG1 . THR B 2 146 ? -19.284 -11.848 -7.367  1   34.51  ? 316 THR B OG1 1 
ATOM   3602 C  CG2 . THR B 2 146 ? -18.129 -10.084 -8.516  1   29.66  ? 316 THR B CG2 1 
ATOM   3603 N  N   . GLN B 2 147 ? -21.796 -12.949 -8.867  1   32.32  ? 317 GLN B N   1 
ATOM   3604 C  CA  . GLN B 2 147 ? -22.555 -14.186 -8.986  1   33.2   ? 317 GLN B CA  1 
ATOM   3605 C  C   . GLN B 2 147 ? -23.43  -14.162 -10.231 1   34.51  ? 317 GLN B C   1 
ATOM   3606 O  O   . GLN B 2 147 ? -23.504 -15.159 -10.949 1   37.33  ? 317 GLN B O   1 
ATOM   3607 C  CB  . GLN B 2 147 ? -23.415 -14.445 -7.755  1   33.87  ? 317 GLN B CB  1 
ATOM   3608 C  CG  . GLN B 2 147 ? -22.587 -14.884 -6.563  1   32.51  ? 317 GLN B CG  1 
ATOM   3609 C  CD  . GLN B 2 147 ? -23.388 -15.361 -5.379  1   35.4   ? 317 GLN B CD  1 
ATOM   3610 O  OE1 . GLN B 2 147 ? -22.967 -15.127 -4.246  1   41.22  ? 317 GLN B OE1 1 
ATOM   3611 N  NE2 . GLN B 2 147 ? -24.473 -16.099 -5.596  1   35.09  ? 317 GLN B NE2 1 
ATOM   3612 N  N   . TYR B 2 148 ? -24.095 -13.022 -10.458 1   34.02  ? 318 TYR B N   1 
ATOM   3613 C  CA  . TYR B 2 148 ? -25.013 -12.904 -11.579 1   35.22  ? 318 TYR B CA  1 
ATOM   3614 C  C   . TYR B 2 148 ? -24.227 -13.107 -12.868 1   36.12  ? 318 TYR B C   1 
ATOM   3615 O  O   . TYR B 2 148 ? -24.74  -13.704 -13.804 1   37.17  ? 318 TYR B O   1 
ATOM   3616 C  CB  . TYR B 2 148 ? -25.763 -11.568 -11.568 1   34.17  ? 318 TYR B CB  1 
ATOM   3617 C  CG  . TYR B 2 148 ? -26.663 -11.312 -10.366 1   33.84  ? 318 TYR B CG  1 
ATOM   3618 C  CD1 . TYR B 2 148 ? -27.015 -12.326 -9.48   1   34.46  ? 318 TYR B CD1 1 
ATOM   3619 C  CD2 . TYR B 2 148 ? -27.213 -10.054 -10.136 1   35.09  ? 318 TYR B CD2 1 
ATOM   3620 C  CE1 . TYR B 2 148 ? -27.863 -12.106 -8.401  1   34.39  ? 318 TYR B CE1 1 
ATOM   3621 C  CE2 . TYR B 2 148 ? -28.04  -9.808  -9.046  1   35.43  ? 318 TYR B CE2 1 
ATOM   3622 C  CZ  . TYR B 2 148 ? -28.386 -10.843 -8.189  1   34.72  ? 318 TYR B CZ  1 
ATOM   3623 O  OH  . TYR B 2 148 ? -29.214 -10.629 -7.133  1   34.42  ? 318 TYR B OH  1 
ATOM   3624 N  N   . PHE B 2 149 ? -22.969 -12.646 -12.895 1   35.88  ? 319 PHE B N   1 
ATOM   3625 C  CA  . PHE B 2 149 ? -22.236 -12.635 -14.15  1   37.3   ? 319 PHE B CA  1 
ATOM   3626 C  C   . PHE B 2 149 ? -22.046 -14.063 -14.641 1   38.54  ? 319 PHE B C   1 
ATOM   3627 O  O   . PHE B 2 149 ? -21.814 -14.283 -15.836 1   38.58  ? 319 PHE B O   1 
ATOM   3628 C  CB  . PHE B 2 149 ? -20.851 -12.028 -13.959 1   36.14  ? 319 PHE B CB  1 
ATOM   3629 C  CG  . PHE B 2 149 ? -20.846 -10.544 -13.63  1   36.44  ? 319 PHE B CG  1 
ATOM   3630 C  CD1 . PHE B 2 149 ? -21.95  -9.749  -13.927 1   37.65  ? 319 PHE B CD1 1 
ATOM   3631 C  CD2 . PHE B 2 149 ? -19.721 -9.944  -13.057 1   33.3   ? 319 PHE B CD2 1 
ATOM   3632 C  CE1 . PHE B 2 149 ? -21.942 -8.389  -13.627 1   37.52  ? 319 PHE B CE1 1 
ATOM   3633 C  CE2 . PHE B 2 149 ? -19.706 -8.584  -12.787 1   34.57  ? 319 PHE B CE2 1 
ATOM   3634 C  CZ  . PHE B 2 149 ? -20.819 -7.804  -13.08  1   36.43  ? 319 PHE B CZ  1 
ATOM   3635 N  N   . LEU B 2 150 ? -22.114 -15.021 -13.701 1   36.82  ? 320 LEU B N   1 
ATOM   3636 C  CA  . LEU B 2 150 ? -21.852 -16.409 -14.041 1   38.19  ? 320 LEU B CA  1 
ATOM   3637 C  C   . LEU B 2 150 ? -22.931 -16.934 -14.99  1   41.39  ? 320 LEU B C   1 
ATOM   3638 O  O   . LEU B 2 150 ? -22.768 -17.995 -15.571 1   41.33  ? 320 LEU B O   1 
ATOM   3639 C  CB  . LEU B 2 150 ? -21.687 -17.278 -12.796 1   35.91  ? 320 LEU B CB  1 
ATOM   3640 C  CG  . LEU B 2 150 ? -20.455 -16.965 -11.951 1   36.53  ? 320 LEU B CG  1 
ATOM   3641 C  CD1 . LEU B 2 150 ? -20.437 -17.807 -10.677 1   34.22  ? 320 LEU B CD1 1 
ATOM   3642 C  CD2 . LEU B 2 150 ? -19.213 -17.181 -12.813 1   33.93  ? 320 LEU B CD2 1 
ATOM   3643 N  N   . HIS B 2 151 ? -24.025 -16.182 -15.152 1   42.74  ? 321 HIS B N   1 
ATOM   3644 C  CA  . HIS B 2 151 ? -25.148 -16.615 -15.967 1   43.27  ? 321 HIS B CA  1 
ATOM   3645 C  C   . HIS B 2 151 ? -25.066 -16.057 -17.392 1   49.41  ? 321 HIS B C   1 
ATOM   3646 O  O   . HIS B 2 151 ? -25.937 -16.353 -18.217 1   53.93  ? 321 HIS B O   1 
ATOM   3647 C  CB  . HIS B 2 151 ? -26.431 -16.191 -15.256 1   41.2   ? 321 HIS B CB  1 
ATOM   3648 C  CG  . HIS B 2 151 ? -26.686 -16.991 -14.024 1   39.91  ? 321 HIS B CG  1 
ATOM   3649 N  ND1 . HIS B 2 151 ? -27.715 -17.91  -13.922 1   40.45  ? 321 HIS B ND1 1 
ATOM   3650 C  CD2 . HIS B 2 151 ? -26.059 -16.994 -12.842 1   36.8   ? 321 HIS B CD2 1 
ATOM   3651 C  CE1 . HIS B 2 151 ? -27.689 -18.455 -12.711 1   37.49  ? 321 HIS B CE1 1 
ATOM   3652 N  NE2 . HIS B 2 151 ? -26.696 -17.908 -12.043 1   37     ? 321 HIS B NE2 1 
ATOM   3653 N  N   . GLN B 2 152 ? -24.058 -15.225 -17.632 1   47.9   ? 322 GLN B N   1 
ATOM   3654 C  CA  . GLN B 2 152 ? -23.866 -14.631 -18.971 1   52.35  ? 322 GLN B CA  1 
ATOM   3655 C  C   . GLN B 2 152 ? -23.52  -15.741 -19.957 1   58.53  ? 322 GLN B C   1 
ATOM   3656 O  O   . GLN B 2 152 ? -22.623 -16.545 -19.654 1   54.85  ? 322 GLN B O   1 
ATOM   3657 C  CB  . GLN B 2 152 ? -22.72  -13.627 -19.028 1   51.38  ? 322 GLN B CB  1 
ATOM   3658 C  CG  . GLN B 2 152 ? -22.848 -12.443 -18.08  1   60.36  ? 322 GLN B CG  1 
ATOM   3659 C  CD  . GLN B 2 152 ? -21.556 -11.669 -17.955 1   69.65  ? 322 GLN B CD  1 
ATOM   3660 O  OE1 . GLN B 2 152 ? -20.508 -12.22  -17.609 1   91.23  ? 322 GLN B OE1 1 
ATOM   3661 N  NE2 . GLN B 2 152 ? -21.622 -10.375 -18.222 1   59.27  ? 322 GLN B NE2 1 
ATOM   3662 N  N   . GLN B 2 153 ? -24.214 -15.763 -21.089 1   70.35  ? 323 GLN B N   1 
ATOM   3663 C  CA  . GLN B 2 153 ? -23.927 -16.76  -22.147 1   84.41  ? 323 GLN B CA  1 
ATOM   3664 C  C   . GLN B 2 153 ? -23.809 -16.008 -23.482 1   83.77  ? 323 GLN B C   1 
ATOM   3665 O  O   . GLN B 2 153 ? -24.856 -15.716 -24.09  1   84.44  ? 323 GLN B O   1 
ATOM   3666 C  CB  . GLN B 2 153 ? -25.035 -17.812 -22.181 1   97.49  ? 323 GLN B CB  1 
ATOM   3667 C  CG  . GLN B 2 153 ? -24.781 -19.018 -21.285 1   108.35 ? 323 GLN B CG  1 
ATOM   3668 C  CD  . GLN B 2 153 ? -26.002 -19.894 -21.112 1   119.43 ? 323 GLN B CD  1 
ATOM   3669 O  OE1 . GLN B 2 153 ? -26.938 -19.862 -21.917 1   109.32 ? 323 GLN B OE1 1 
ATOM   3670 N  NE2 . GLN B 2 153 ? -26.004 -20.69  -20.053 1   139.26 ? 323 GLN B NE2 1 
ATOM   3671 N  N   . PRO B 2 154 ? -22.591 -15.647 -23.937 1   72.22  ? 324 PRO B N   1 
ATOM   3672 C  CA  . PRO B 2 154 ? -21.39  -15.93  -23.173 1   61.94  ? 324 PRO B CA  1 
ATOM   3673 C  C   . PRO B 2 154 ? -20.95  -14.79  -22.285 1   57.32  ? 324 PRO B C   1 
ATOM   3674 O  O   . PRO B 2 154 ? -21.638 -13.766 -22.2   1   54.73  ? 324 PRO B O   1 
ATOM   3675 C  CB  . PRO B 2 154 ? -20.43  -16.132 -24.326 1   63.51  ? 324 PRO B CB  1 
ATOM   3676 C  CG  . PRO B 2 154 ? -20.816 -15.043 -25.296 1   67.51  ? 324 PRO B CG  1 
ATOM   3677 C  CD  . PRO B 2 154 ? -22.331 -14.982 -25.198 1   69.33  ? 324 PRO B CD  1 
ATOM   3678 N  N   . ALA B 2 155 ? -19.797 -14.961 -21.645 1   53.09  ? 325 ALA B N   1 
ATOM   3679 C  CA  . ALA B 2 155 ? -19.256 -13.922 -20.747 1   47.78  ? 325 ALA B CA  1 
ATOM   3680 C  C   . ALA B 2 155 ? -18.891 -12.69  -21.564 1   47.83  ? 325 ALA B C   1 
ATOM   3681 O  O   . ALA B 2 155 ? -18.426 -12.84  -22.702 1   53.09  ? 325 ALA B O   1 
ATOM   3682 C  CB  . ALA B 2 155 ? -18.098 -14.48  -19.974 1   43.07  ? 325 ALA B CB  1 
ATOM   3683 N  N   . ASN B 2 156 ? -19.062 -11.509 -20.987 1   46.18  ? 326 ASN B N   1 
ATOM   3684 C  CA  . ASN B 2 156 ? -18.878 -10.272 -21.736 1   46.91  ? 326 ASN B CA  1 
ATOM   3685 C  C   . ASN B 2 156 ? -18.425 -9.176  -20.78  1   48.37  ? 326 ASN B C   1 
ATOM   3686 O  O   . ASN B 2 156 ? -19.205 -8.76   -19.924 1   52.36  ? 326 ASN B O   1 
ATOM   3687 C  CB  . ASN B 2 156 ? -20.159 -9.837  -22.441 1   45.12  ? 326 ASN B CB  1 
ATOM   3688 C  CG  . ASN B 2 156 ? -19.961 -8.64   -23.342 1   47.73  ? 326 ASN B CG  1 
ATOM   3689 O  OD1 . ASN B 2 156 ? -19.426 -7.609  -22.923 1   51.63  ? 326 ASN B OD1 1 
ATOM   3690 N  ND2 . ASN B 2 156 ? -20.395 -8.737  -24.589 1   47.97  ? 326 ASN B ND2 1 
ATOM   3691 N  N   . CYS B 2 157 ? -17.182 -8.698  -20.96  1   48.62  ? 327 CYS B N   1 
ATOM   3692 C  CA  . CYS B 2 157 ? -16.512 -7.796  -20.025 1   48.49  ? 327 CYS B CA  1 
ATOM   3693 C  C   . CYS B 2 157 ? -17.132 -6.389  -20.034 1   45.03  ? 327 CYS B C   1 
ATOM   3694 O  O   . CYS B 2 157 ? -17.101 -5.718  -19.004 1   41.82  ? 327 CYS B O   1 
ATOM   3695 C  CB  . CYS B 2 157 ? -14.994 -7.814  -20.197 1   52.73  ? 327 CYS B CB  1 
ATOM   3696 S  SG  . CYS B 2 157 ? -14.467 -7.197  -21.824 1   75.3   ? 327 CYS B SG  1 
ATOM   3697 N  N   . LYS B 2 158 ? -17.737 -5.965  -21.158 1   45.36  ? 328 LYS B N   1 
ATOM   3698 C  CA  . LYS B 2 158 ? -18.43  -4.684  -21.218 1   47.28  ? 328 LYS B CA  1 
ATOM   3699 C  C   . LYS B 2 158 ? -19.69  -4.73   -20.358 1   46.78  ? 328 LYS B C   1 
ATOM   3700 O  O   . LYS B 2 158 ? -20.033 -3.754  -19.688 1   47.76  ? 328 LYS B O   1 
ATOM   3701 C  CB  . LYS B 2 158 ? -18.761 -4.214  -22.634 1   54.52  ? 328 LYS B CB  1 
ATOM   3702 C  CG  . LYS B 2 158 ? -17.54  -3.722  -23.376 1   61.48  ? 328 LYS B CG  1 
ATOM   3703 C  CD  . LYS B 2 158 ? -17.833 -3.098  -24.731 1   78.45  ? 328 LYS B CD  1 
ATOM   3704 C  CE  . LYS B 2 158 ? -16.533 -2.716  -25.396 1   99.72  ? 328 LYS B CE  1 
ATOM   3705 N  NZ  . LYS B 2 158 ? -15.644 -1.926  -24.527 1   96.55  ? 328 LYS B NZ  1 
ATOM   3706 N  N   . VAL B 2 159 ? -20.357 -5.887  -20.367 1   44.97  ? 329 VAL B N   1 
ATOM   3707 C  CA  . VAL B 2 159 ? -21.519 -6.11   -19.529 1   40.63  ? 329 VAL B CA  1 
ATOM   3708 C  C   . VAL B 2 159 ? -21.067 -6.029  -18.08  1   39.81  ? 329 VAL B C   1 
ATOM   3709 O  O   . VAL B 2 159 ? -21.682 -5.304  -17.297 1   37.91  ? 329 VAL B O   1 
ATOM   3710 C  CB  . VAL B 2 159 ? -22.326 -7.389  -19.826 1   39.64  ? 329 VAL B CB  1 
ATOM   3711 C  CG1 . VAL B 2 159 ? -23.417 -7.628  -18.784 1   37.81  ? 329 VAL B CG1 1 
ATOM   3712 C  CG2 . VAL B 2 159 ? -22.96  -7.309  -21.207 1   39.77  ? 329 VAL B CG2 1 
ATOM   3713 N  N   . GLU B 2 160 ? -19.964 -6.732  -17.766 1   39.01  ? 330 GLU B N   1 
ATOM   3714 C  CA  . GLU B 2 160 ? -19.502 -6.799  -16.389 1   37.4   ? 330 GLU B CA  1 
ATOM   3715 C  C   . GLU B 2 160 ? -19.128 -5.4    -15.923 1   35.97  ? 330 GLU B C   1 
ATOM   3716 O  O   . GLU B 2 160 ? -19.695 -4.928  -14.957 1   39.06  ? 330 GLU B O   1 
ATOM   3717 C  CB  . GLU B 2 160 ? -18.394 -7.821  -16.173 1   38.04  ? 330 GLU B CB  1 
ATOM   3718 C  CG  . GLU B 2 160 ? -18.772 -9.209  -16.669 1   41     ? 330 GLU B CG  1 
ATOM   3719 C  CD  . GLU B 2 160 ? -17.814 -10.289 -16.235 1   42.62  ? 330 GLU B CD  1 
ATOM   3720 O  OE1 . GLU B 2 160 ? -16.992 -10.049 -15.331 1   44.51  ? 330 GLU B OE1 1 
ATOM   3721 O  OE2 . GLU B 2 160 ? -17.898 -11.381 -16.809 1   48.69  ? 330 GLU B OE2 1 
ATOM   3722 N  N   . SER B 2 161 ? -18.28  -4.705  -16.689 1   36.03  ? 331 SER B N   1 
ATOM   3723 C  CA  . SER B 2 161 ? -17.859 -3.368  -16.317 1   36.54  ? 331 SER B CA  1 
ATOM   3724 C  C   . SER B 2 161 ? -19.061 -2.418  -16.244 1   38.7   ? 331 SER B C   1 
ATOM   3725 O  O   . SER B 2 161 ? -19.176 -1.64   -15.3   1   36.37  ? 331 SER B O   1 
ATOM   3726 C  CB  . SER B 2 161 ? -16.754 -2.854  -17.204 1   36.03  ? 331 SER B CB  1 
ATOM   3727 O  OG  . SER B 2 161 ? -15.576 -3.627  -17.006 1   37.96  ? 331 SER B OG  1 
ATOM   3728 N  N   . LEU B 2 162 ? -19.971 -2.497  -17.218 1   39.03  ? 332 LEU B N   1 
ATOM   3729 C  CA  . LEU B 2 162 ? -21.084 -1.564  -17.233 1   40.6   ? 332 LEU B CA  1 
ATOM   3730 C  C   . LEU B 2 162 ? -21.952 -1.768  -15.986 1   38.67  ? 332 LEU B C   1 
ATOM   3731 O  O   . LEU B 2 162 ? -22.495 -0.812  -15.436 1   38.8   ? 332 LEU B O   1 
ATOM   3732 C  CB  . LEU B 2 162 ? -21.862 -1.599  -18.558 1   38.92  ? 332 LEU B CB  1 
ATOM   3733 C  CG  . LEU B 2 162 ? -23.041 -0.625  -18.678 1   39.16  ? 332 LEU B CG  1 
ATOM   3734 C  CD1 . LEU B 2 162 ? -22.69  0.825   -18.35  1   39.12  ? 332 LEU B CD1 1 
ATOM   3735 C  CD2 . LEU B 2 162 ? -23.655 -0.684  -20.073 1   39.71  ? 332 LEU B CD2 1 
ATOM   3736 N  N   . ALA B 2 163 ? -22.104 -3.028  -15.569 1   35.65  ? 333 ALA B N   1 
ATOM   3737 C  CA  . ALA B 2 163 ? -22.96  -3.331  -14.396 1   33.97  ? 333 ALA B CA  1 
ATOM   3738 C  C   . ALA B 2 163 ? -22.351 -2.692  -13.148 1   34.08  ? 333 ALA B C   1 
ATOM   3739 O  O   . ALA B 2 163 ? -23.068 -1.961  -12.432 1   32.86  ? 333 ALA B O   1 
ATOM   3740 C  CB  . ALA B 2 163 ? -23.113 -4.827  -14.235 1   31.93  ? 333 ALA B CB  1 
ATOM   3741 N  N   . MET B 2 164 ? -21.066 -2.959  -12.899 1   36.4   ? 334 MET B N   1 
ATOM   3742 C  CA  . MET B 2 164 ? -20.374 -2.36   -11.728 1   38.64  ? 334 MET B CA  1 
ATOM   3743 C  C   . MET B 2 164 ? -20.561 -0.837  -11.767 1   37.74  ? 334 MET B C   1 
ATOM   3744 O  O   . MET B 2 164 ? -20.938 -0.26   -10.727 1   39.13  ? 334 MET B O   1 
ATOM   3745 C  CB  . MET B 2 164 ? -18.879 -2.689  -11.754 1   45.22  ? 334 MET B CB  1 
ATOM   3746 C  CG  . MET B 2 164 ? -18.583 -4.153  -11.999 1   50.53  ? 334 MET B CG  1 
ATOM   3747 S  SD  . MET B 2 164 ? -18.28  -5.064  -10.472 1   70.05  ? 334 MET B SD  1 
ATOM   3748 C  CE  . MET B 2 164 ? -16.486 -4.961  -10.422 1   62.24  ? 334 MET B CE  1 
ATOM   3749 N  N   . PHE B 2 165 ? -20.303 -0.222  -12.923 1   39.77  ? 335 PHE B N   1 
ATOM   3750 C  CA  . PHE B 2 165 ? -20.468 1.248   -13.069 1   38.91  ? 335 PHE B CA  1 
ATOM   3751 C  C   . PHE B 2 165 ? -21.841 1.657   -12.545 1   40.72  ? 335 PHE B C   1 
ATOM   3752 O  O   . PHE B 2 165 ? -21.917 2.591   -11.718 1   42.14  ? 335 PHE B O   1 
ATOM   3753 C  CB  . PHE B 2 165 ? -20.277 1.613   -14.543 1   36.5   ? 335 PHE B CB  1 
ATOM   3754 C  CG  . PHE B 2 165 ? -20.65  3.045   -14.899 1   35.21  ? 335 PHE B CG  1 
ATOM   3755 C  CD1 . PHE B 2 165 ? -19.984 4.119   -14.323 1   35.57  ? 335 PHE B CD1 1 
ATOM   3756 C  CD2 . PHE B 2 165 ? -21.666 3.311   -15.809 1   34.8   ? 335 PHE B CD2 1 
ATOM   3757 C  CE1 . PHE B 2 165 ? -20.326 5.421   -14.648 1   37.45  ? 335 PHE B CE1 1 
ATOM   3758 C  CE2 . PHE B 2 165 ? -22.003 4.616   -16.132 1   37.41  ? 335 PHE B CE2 1 
ATOM   3759 C  CZ  . PHE B 2 165 ? -21.333 5.667   -15.551 1   36.94  ? 335 PHE B CZ  1 
ATOM   3760 N  N   . LEU B 2 166 ? -22.899 0.978   -12.999 1   40.39  ? 336 LEU B N   1 
ATOM   3761 C  CA  . LEU B 2 166 ? -24.239 1.366   -12.602 1   39.37  ? 336 LEU B CA  1 
ATOM   3762 C  C   . LEU B 2 166 ? -24.414 1.097   -11.111 1   40     ? 336 LEU B C   1 
ATOM   3763 O  O   . LEU B 2 166 ? -24.959 1.931   -10.381 1   42.84  ? 336 LEU B O   1 
ATOM   3764 C  CB  . LEU B 2 166 ? -25.217 0.588   -13.476 1   36.28  ? 336 LEU B CB  1 
ATOM   3765 C  CG  . LEU B 2 166 ? -25.147 0.954   -14.954 1   34.91  ? 336 LEU B CG  1 
ATOM   3766 C  CD1 . LEU B 2 166 ? -25.835 -0.133  -15.756 1   35.83  ? 336 LEU B CD1 1 
ATOM   3767 C  CD2 . LEU B 2 166 ? -25.8   2.322   -15.158 1   34.49  ? 336 LEU B CD2 1 
ATOM   3768 N  N   . GLY B 2 167 ? -23.882 -0.037  -10.643 1   37.7   ? 337 GLY B N   1 
ATOM   3769 C  CA  . GLY B 2 167 ? -24.017 -0.356  -9.226  1   36.34  ? 337 GLY B CA  1 
ATOM   3770 C  C   . GLY B 2 167 ? -23.327 0.687   -8.361  1   36.31  ? 337 GLY B C   1 
ATOM   3771 O  O   . GLY B 2 167 ? -23.796 0.986   -7.273  1   39.63  ? 337 GLY B O   1 
ATOM   3772 N  N   . GLU B 2 168 ? -22.226 1.257   -8.865  1   37.22  ? 338 GLU B N   1 
ATOM   3773 C  CA  . GLU B 2 168 ? -21.459 2.216   -8.093  1   38.44  ? 338 GLU B CA  1 
ATOM   3774 C  C   . GLU B 2 168 ? -22.244 3.53    -8.04   1   40.81  ? 338 GLU B C   1 
ATOM   3775 O  O   . GLU B 2 168 ? -22.349 4.158   -6.986  1   43.87  ? 338 GLU B O   1 
ATOM   3776 C  CB  . GLU B 2 168 ? -20.05  2.281   -8.686  1   39.1   ? 338 GLU B CB  1 
ATOM   3777 C  CG  . GLU B 2 168 ? -18.956 2.229   -7.627  1   37.86  ? 338 GLU B CG  1 
ATOM   3778 C  CD  . GLU B 2 168 ? -17.559 2.077   -8.202  1   37.5   ? 338 GLU B CD  1 
ATOM   3779 O  OE1 . GLU B 2 168 ? -16.813 3.089   -8.27   1   36.52  ? 338 GLU B OE1 1 
ATOM   3780 O  OE2 . GLU B 2 168 ? -17.209 0.935   -8.563  1   34.85  ? 338 GLU B OE2 1 
ATOM   3781 N  N   . LEU B 2 169 ? -22.843 3.916   -9.172  1   39.53  ? 339 LEU B N   1 
ATOM   3782 C  CA  . LEU B 2 169 ? -23.558 5.172   -9.28   1   40.04  ? 339 LEU B CA  1 
ATOM   3783 C  C   . LEU B 2 169 ? -24.597 5.248   -8.163  1   41.87  ? 339 LEU B C   1 
ATOM   3784 O  O   . LEU B 2 169 ? -24.805 6.305   -7.573  1   46.3   ? 339 LEU B O   1 
ATOM   3785 C  CB  . LEU B 2 169 ? -24.2   5.264   -10.666 1   38.98  ? 339 LEU B CB  1 
ATOM   3786 C  CG  . LEU B 2 169 ? -23.31  5.678   -11.847 1   38.21  ? 339 LEU B CG  1 
ATOM   3787 C  CD1 . LEU B 2 169 ? -24.136 5.888   -13.106 1   35.71  ? 339 LEU B CD1 1 
ATOM   3788 C  CD2 . LEU B 2 169 ? -22.5   6.932   -11.547 1   38.66  ? 339 LEU B CD2 1 
ATOM   3789 N  N   . SER B 2 170 ? -25.271 4.124   -7.904  1   40.78  ? 340 SER B N   1 
ATOM   3790 C  CA  . SER B 2 170 ? -26.353 4.069   -6.93   1   41.7   ? 340 SER B CA  1 
ATOM   3791 C  C   . SER B 2 170 ? -25.851 4.369   -5.513  1   41.4   ? 340 SER B C   1 
ATOM   3792 O  O   . SER B 2 170 ? -26.644 4.761   -4.683  1   47.04  ? 340 SER B O   1 
ATOM   3793 C  CB  . SER B 2 170 ? -27.067 2.725   -6.969  1   41.26  ? 340 SER B CB  1 
ATOM   3794 O  OG  . SER B 2 170 ? -26.252 1.729   -6.345  1   39.51  ? 340 SER B OG  1 
ATOM   3795 N  N   . LEU B 2 171 ? -24.566 4.151   -5.208  1   40.58  ? 341 LEU B N   1 
ATOM   3796 C  CA  . LEU B 2 171 ? -24.025 4.417   -3.883  1   40.24  ? 341 LEU B CA  1 
ATOM   3797 C  C   . LEU B 2 171 ? -24.146 5.899   -3.54   1   45.18  ? 341 LEU B C   1 
ATOM   3798 O  O   . LEU B 2 171 ? -24.211 6.245   -2.36   1   47.93  ? 341 LEU B O   1 
ATOM   3799 C  CB  . LEU B 2 171 ? -22.562 3.995   -3.816  1   36.78  ? 341 LEU B CB  1 
ATOM   3800 C  CG  . LEU B 2 171 ? -22.282 2.505   -4.022  1   34.24  ? 341 LEU B CG  1 
ATOM   3801 C  CD1 . LEU B 2 171 ? -20.791 2.275   -4.207  1   33.92  ? 341 LEU B CD1 1 
ATOM   3802 C  CD2 . LEU B 2 171 ? -22.812 1.672   -2.86   1   31.95  ? 341 LEU B CD2 1 
ATOM   3803 N  N   . ILE B 2 172 ? -24.173 6.758   -4.576  1   44.83  ? 342 ILE B N   1 
ATOM   3804 C  CA  . ILE B 2 172 ? -23.962 8.186   -4.394  1   41.24  ? 342 ILE B CA  1 
ATOM   3805 C  C   . ILE B 2 172 ? -25.232 8.815   -3.837  1   42.77  ? 342 ILE B C   1 
ATOM   3806 O  O   . ILE B 2 172 ? -25.148 9.847   -3.184  1   44.28  ? 342 ILE B O   1 
ATOM   3807 C  CB  . ILE B 2 172 ? -23.504 8.878   -5.697  1   40.62  ? 342 ILE B CB  1 
ATOM   3808 C  CG1 . ILE B 2 172 ? -22.148 8.372   -6.19   1   38.43  ? 342 ILE B CG1 1 
ATOM   3809 C  CG2 . ILE B 2 172 ? -23.488 10.401  -5.543  1   40.4   ? 342 ILE B CG2 1 
ATOM   3810 C  CD1 . ILE B 2 172 ? -20.948 8.987   -5.49   1   37.92  ? 342 ILE B CD1 1 
ATOM   3811 N  N   . ASP B 2 173 ? -26.386 8.206   -4.145  1   43.55  ? 343 ASP B N   1 
ATOM   3812 C  CA  . ASP B 2 173 ? -27.692 8.84    -4.016  1   46.21  ? 343 ASP B CA  1 
ATOM   3813 C  C   . ASP B 2 173 ? -28.569 8.049   -3.034  1   47.45  ? 343 ASP B C   1 
ATOM   3814 O  O   . ASP B 2 173 ? -29.359 7.188   -3.458  1   47.11  ? 343 ASP B O   1 
ATOM   3815 C  CB  . ASP B 2 173 ? -28.34  8.988   -5.387  1   46.6   ? 343 ASP B CB  1 
ATOM   3816 C  CG  . ASP B 2 173 ? -27.679 9.949   -6.372  1   50.2   ? 343 ASP B CG  1 
ATOM   3817 O  OD1 . ASP B 2 173 ? -27.211 11.015  -5.935  1   50.28  ? 343 ASP B OD1 1 
ATOM   3818 O  OD2 . ASP B 2 173 ? -27.659 9.649   -7.584  1   48.1   ? 343 ASP B OD2 1 
ATOM   3819 N  N   . ALA B 2 174 ? -28.425 8.335   -1.727  1   44.07  ? 344 ALA B N   1 
ATOM   3820 C  CA  . ALA B 2 174 ? -29.271 7.726   -0.707  1   44.13  ? 344 ALA B CA  1 
ATOM   3821 C  C   . ALA B 2 174 ? -30.742 7.722   -1.149  1   47.81  ? 344 ALA B C   1 
ATOM   3822 O  O   . ALA B 2 174 ? -31.456 6.731   -0.969  1   49.9   ? 344 ALA B O   1 
ATOM   3823 C  CB  . ALA B 2 174 ? -29.092 8.443   0.604   1   41.87  ? 344 ALA B CB  1 
ATOM   3824 N  N   . ASP B 2 175 ? -31.178 8.829   -1.758  1   48.34  ? 345 ASP B N   1 
ATOM   3825 C  CA  . ASP B 2 175 ? -32.472 8.888   -2.414  1   55.7   ? 345 ASP B CA  1 
ATOM   3826 C  C   . ASP B 2 175 ? -32.261 8.814   -3.925  1   53.64  ? 345 ASP B C   1 
ATOM   3827 O  O   . ASP B 2 175 ? -31.811 9.79    -4.53   1   53.72  ? 345 ASP B O   1 
ATOM   3828 C  CB  . ASP B 2 175 ? -33.308 10.102  -2.005  1   63.56  ? 345 ASP B CB  1 
ATOM   3829 C  CG  . ASP B 2 175 ? -34.818 9.924   -2.185  1   70.24  ? 345 ASP B CG  1 
ATOM   3830 O  OD1 . ASP B 2 175 ? -35.316 8.868   -1.7    1   103.04 ? 345 ASP B OD1 1 
ATOM   3831 O  OD2 . ASP B 2 175 ? -35.464 10.767  -2.86   1   58.98  ? 345 ASP B OD2 1 
ATOM   3832 N  N   . PRO B 2 176 ? -32.686 7.705   -4.586  1   49.25  ? 346 PRO B N   1 
ATOM   3833 C  CA  . PRO B 2 176 ? -33.573 6.714   -3.948  1   45.61  ? 346 PRO B CA  1 
ATOM   3834 C  C   . PRO B 2 176 ? -32.985 5.431   -3.377  1   44.24  ? 346 PRO B C   1 
ATOM   3835 O  O   . PRO B 2 176 ? -33.724 4.591   -2.877  1   48.53  ? 346 PRO B O   1 
ATOM   3836 C  CB  . PRO B 2 176 ? -34.464 6.392   -5.142  1   45.3   ? 346 PRO B CB  1 
ATOM   3837 C  CG  . PRO B 2 176 ? -33.501 6.394   -6.309  1   45.95  ? 346 PRO B CG  1 
ATOM   3838 C  CD  . PRO B 2 176 ? -32.407 7.417   -6      1   44.98  ? 346 PRO B CD  1 
ATOM   3839 N  N   . TYR B 2 177 ? -31.668 5.257   -3.487  1   40.02  ? 347 TYR B N   1 
ATOM   3840 C  CA  . TYR B 2 177 ? -31.155 3.903   -3.451  1   39.61  ? 347 TYR B CA  1 
ATOM   3841 C  C   . TYR B 2 177 ? -31.259 3.222   -2.078  1   41.03  ? 347 TYR B C   1 
ATOM   3842 O  O   . TYR B 2 177 ? -31.271 1.996   -2.05   1   40.81  ? 347 TYR B O   1 
ATOM   3843 C  CB  . TYR B 2 177 ? -29.883 3.754   -4.29   1   41.83  ? 347 TYR B CB  1 
ATOM   3844 C  CG  . TYR B 2 177 ? -30.187 3.955   -5.77   1   42.64  ? 347 TYR B CG  1 
ATOM   3845 C  CD1 . TYR B 2 177 ? -30.87  2.987   -6.506  1   39.76  ? 347 TYR B CD1 1 
ATOM   3846 C  CD2 . TYR B 2 177 ? -29.821 5.136   -6.41   1   42.37  ? 347 TYR B CD2 1 
ATOM   3847 C  CE1 . TYR B 2 177 ? -31.167 3.186   -7.839  1   40.78  ? 347 TYR B CE1 1 
ATOM   3848 C  CE2 . TYR B 2 177 ? -30.093 5.339   -7.749  1   42.65  ? 347 TYR B CE2 1 
ATOM   3849 C  CZ  . TYR B 2 177 ? -30.78  4.37    -8.46   1   45.12  ? 347 TYR B CZ  1 
ATOM   3850 O  OH  . TYR B 2 177 ? -31.065 4.65    -9.773  1   49.52  ? 347 TYR B OH  1 
ATOM   3851 N  N   . LEU B 2 178 ? -31.376 3.966   -0.959  1   41.98  ? 348 LEU B N   1 
ATOM   3852 C  CA  . LEU B 2 178 ? -31.545 3.349   0.357   1   40.55  ? 348 LEU B CA  1 
ATOM   3853 C  C   . LEU B 2 178 ? -32.776 2.448   0.377   1   42.22  ? 348 LEU B C   1 
ATOM   3854 O  O   . LEU B 2 178 ? -32.822 1.497   1.138   1   43.73  ? 348 LEU B O   1 
ATOM   3855 C  CB  . LEU B 2 178 ? -31.661 4.367   1.484   1   43.95  ? 348 LEU B CB  1 
ATOM   3856 C  CG  . LEU B 2 178 ? -30.381 5.148   1.8     1   47.89  ? 348 LEU B CG  1 
ATOM   3857 C  CD1 . LEU B 2 178 ? -30.675 6.064   2.997   1   47.1   ? 348 LEU B CD1 1 
ATOM   3858 C  CD2 . LEU B 2 178 ? -29.188 4.231   2.062   1   41.91  ? 348 LEU B CD2 1 
ATOM   3859 N  N   . LYS B 2 179 ? -33.777 2.779   -0.442  1   46.59  ? 349 LYS B N   1 
ATOM   3860 C  CA  . LYS B 2 179 ? -34.994 1.994   -0.582  1   49.29  ? 349 LYS B CA  1 
ATOM   3861 C  C   . LYS B 2 179 ? -34.666 0.552   -0.98   1   43.57  ? 349 LYS B C   1 
ATOM   3862 O  O   . LYS B 2 179 ? -35.42  -0.343  -0.663  1   46.1   ? 349 LYS B O   1 
ATOM   3863 C  CB  . LYS B 2 179 ? -35.917 2.633   -1.636  1   54.69  ? 349 LYS B CB  1 
ATOM   3864 C  CG  . LYS B 2 179 ? -36.79  3.802   -1.149  1   64.48  ? 349 LYS B CG  1 
ATOM   3865 C  CD  . LYS B 2 179 ? -36.886 5.13    -1.904  1   68.49  ? 349 LYS B CD  1 
ATOM   3866 C  CE  . LYS B 2 179 ? -37.29  4.99    -3.342  1   68.25  ? 349 LYS B CE  1 
ATOM   3867 N  NZ  . LYS B 2 179 ? -38.464 4.136   -3.528  1   64.81  ? 349 LYS B NZ  1 
ATOM   3868 N  N   . TYR B 2 180 ? -33.562 0.312   -1.684  1   38.62  ? 350 TYR B N   1 
ATOM   3869 C  CA  . TYR B 2 180 ? -33.382 -0.98   -2.329  1   38.16  ? 350 TYR B CA  1 
ATOM   3870 C  C   . TYR B 2 180 ? -32.24  -1.769  -1.68   1   39.19  ? 350 TYR B C   1 
ATOM   3871 O  O   . TYR B 2 180 ? -31.212 -1.199  -1.301  1   36.98  ? 350 TYR B O   1 
ATOM   3872 C  CB  . TYR B 2 180 ? -33.119 -0.822  -3.834  1   37.16  ? 350 TYR B CB  1 
ATOM   3873 C  CG  . TYR B 2 180 ? -34.2   -0.103  -4.624  1   38.32  ? 350 TYR B CG  1 
ATOM   3874 C  CD1 . TYR B 2 180 ? -35.472 -0.671  -4.805  1   39.47  ? 350 TYR B CD1 1 
ATOM   3875 C  CD2 . TYR B 2 180 ? -33.954 1.149   -5.178  1   37.03  ? 350 TYR B CD2 1 
ATOM   3876 C  CE1 . TYR B 2 180 ? -36.467 -0.023  -5.53   1   37.99  ? 350 TYR B CE1 1 
ATOM   3877 C  CE2 . TYR B 2 180 ? -34.947 1.807   -5.888  1   38.88  ? 350 TYR B CE2 1 
ATOM   3878 C  CZ  . TYR B 2 180 ? -36.187 1.22    -6.06   1   38.75  ? 350 TYR B CZ  1 
ATOM   3879 O  OH  . TYR B 2 180 ? -37.096 1.916   -6.758  1   42.35  ? 350 TYR B OH  1 
ATOM   3880 N  N   . LEU B 2 181 ? -32.446 -3.097  -1.587  1   40.6   ? 351 LEU B N   1 
ATOM   3881 C  CA  . LEU B 2 181 ? -31.457 -4.075  -1.144  1   37.31  ? 351 LEU B CA  1 
ATOM   3882 C  C   . LEU B 2 181 ? -30.385 -4.241  -2.219  1   38.13  ? 351 LEU B C   1 
ATOM   3883 O  O   . LEU B 2 181 ? -30.651 -4.114  -3.424  1   35.95  ? 351 LEU B O   1 
ATOM   3884 C  CB  . LEU B 2 181 ? -32.093 -5.43   -0.818  1   38.62  ? 351 LEU B CB  1 
ATOM   3885 C  CG  . LEU B 2 181 ? -33.023 -5.518  0.408   1   42.93  ? 351 LEU B CG  1 
ATOM   3886 C  CD1 . LEU B 2 181 ? -33.652 -6.904  0.491   1   42.9   ? 351 LEU B CD1 1 
ATOM   3887 C  CD2 . LEU B 2 181 ? -32.332 -5.239  1.743   1   40.16  ? 351 LEU B CD2 1 
ATOM   3888 N  N   . PRO B 2 182 ? -29.144 -4.567  -1.794  1   37.98  ? 352 PRO B N   1 
ATOM   3889 C  CA  . PRO B 2 182 ? -28.054 -4.899  -2.723  1   36.27  ? 352 PRO B CA  1 
ATOM   3890 C  C   . PRO B 2 182 ? -28.384 -5.877  -3.851  1   37.29  ? 352 PRO B C   1 
ATOM   3891 O  O   . PRO B 2 182 ? -27.95  -5.689  -4.993  1   39.37  ? 352 PRO B O   1 
ATOM   3892 C  CB  . PRO B 2 182 ? -26.957 -5.476  -1.807  1   34.35  ? 352 PRO B CB  1 
ATOM   3893 C  CG  . PRO B 2 182 ? -27.221 -4.85   -0.459  1   36.37  ? 352 PRO B CG  1 
ATOM   3894 C  CD  . PRO B 2 182 ? -28.732 -4.621  -0.379  1   37.96  ? 352 PRO B CD  1 
ATOM   3895 N  N   . SER B 2 183 ? -29.132 -6.937  -3.517  1   36.24  ? 353 SER B N   1 
ATOM   3896 C  CA  . SER B 2 183 ? -29.377 -8.032  -4.444  1   32.74  ? 353 SER B CA  1 
ATOM   3897 C  C   . SER B 2 183 ? -30.285 -7.524  -5.556  1   36.2   ? 353 SER B C   1 
ATOM   3898 O  O   . SER B 2 183 ? -30.204 -8.017  -6.679  1   37.95  ? 353 SER B O   1 
ATOM   3899 C  CB  . SER B 2 183 ? -29.972 -9.223  -3.725  1   32.01  ? 353 SER B CB  1 
ATOM   3900 O  OG  . SER B 2 183 ? -31.269 -8.951  -3.216  1   30.15  ? 353 SER B OG  1 
ATOM   3901 N  N   . VAL B 2 184 ? -31.112 -6.509  -5.226  1   35.43  ? 354 VAL B N   1 
ATOM   3902 C  CA  . VAL B 2 184 ? -32.061 -5.937  -6.164  1   33.48  ? 354 VAL B CA  1 
ATOM   3903 C  C   . VAL B 2 184 ? -31.379 -4.919  -7.081  1   35.74  ? 354 VAL B C   1 
ATOM   3904 O  O   . VAL B 2 184 ? -31.633 -4.903  -8.289  1   39.75  ? 354 VAL B O   1 
ATOM   3905 C  CB  . VAL B 2 184 ? -33.273 -5.371  -5.412  1   32.39  ? 354 VAL B CB  1 
ATOM   3906 C  CG1 . VAL B 2 184 ? -34.214 -4.593  -6.327  1   31.92  ? 354 VAL B CG1 1 
ATOM   3907 C  CG2 . VAL B 2 184 ? -34.014 -6.489  -4.69   1   30.07  ? 354 VAL B CG2 1 
ATOM   3908 N  N   . ILE B 2 185 ? -30.476 -4.105  -6.526  1   34.34  ? 355 ILE B N   1 
ATOM   3909 C  CA  . ILE B 2 185 ? -29.784 -3.11   -7.318  1   35.56  ? 355 ILE B CA  1 
ATOM   3910 C  C   . ILE B 2 185 ? -28.844 -3.805  -8.306  1   39.44  ? 355 ILE B C   1 
ATOM   3911 O  O   . ILE B 2 185 ? -28.722 -3.378  -9.461  1   40.21  ? 355 ILE B O   1 
ATOM   3912 C  CB  . ILE B 2 185 ? -29.024 -2.12   -6.418  1   33.99  ? 355 ILE B CB  1 
ATOM   3913 C  CG1 . ILE B 2 185 ? -29.988 -1.289  -5.579  1   34.21  ? 355 ILE B CG1 1 
ATOM   3914 C  CG2 . ILE B 2 185 ? -28.14  -1.218  -7.283  1   31.92  ? 355 ILE B CG2 1 
ATOM   3915 C  CD1 . ILE B 2 185 ? -29.291 -0.383  -4.585  1   34.03  ? 355 ILE B CD1 1 
ATOM   3916 N  N   . ALA B 2 186 ? -28.148 -4.842  -7.814  1   36.9   ? 356 ALA B N   1 
ATOM   3917 C  CA  . ALA B 2 186 ? -27.264 -5.658  -8.624  1   34.9   ? 356 ALA B CA  1 
ATOM   3918 C  C   . ALA B 2 186 ? -28.062 -6.253  -9.784  1   37.4   ? 356 ALA B C   1 
ATOM   3919 O  O   . ALA B 2 186 ? -27.571 -6.31   -10.911 1   41.39  ? 356 ALA B O   1 
ATOM   3920 C  CB  . ALA B 2 186 ? -26.669 -6.756  -7.777  1   33.48  ? 356 ALA B CB  1 
ATOM   3921 N  N   . ALA B 2 187 ? -29.29  -6.7    -9.494  1   34.37  ? 357 ALA B N   1 
ATOM   3922 C  CA  . ALA B 2 187 ? -30.118 -7.322  -10.507 1   34.73  ? 357 ALA B CA  1 
ATOM   3923 C  C   . ALA B 2 187 ? -30.545 -6.284  -11.553 1   38.12  ? 357 ALA B C   1 
ATOM   3924 O  O   . ALA B 2 187 ? -30.541 -6.546  -12.756 1   35.76  ? 357 ALA B O   1 
ATOM   3925 C  CB  . ALA B 2 187 ? -31.292 -7.984  -9.84   1   32.65  ? 357 ALA B CB  1 
ATOM   3926 N  N   . ALA B 2 188 ? -30.882 -5.083  -11.08  1   37.13  ? 358 ALA B N   1 
ATOM   3927 C  CA  . ALA B 2 188 ? -31.305 -4.032  -11.97  1   38.23  ? 358 ALA B CA  1 
ATOM   3928 C  C   . ALA B 2 188 ? -30.114 -3.588  -12.821 1   39.58  ? 358 ALA B C   1 
ATOM   3929 O  O   . ALA B 2 188 ? -30.231 -3.406  -14.038 1   40.92  ? 358 ALA B O   1 
ATOM   3930 C  CB  . ALA B 2 188 ? -31.878 -2.9    -11.144 1   38.36  ? 358 ALA B CB  1 
ATOM   3931 N  N   . ALA B 2 189 ? -28.96  -3.419  -12.165 1   37.41  ? 359 ALA B N   1 
ATOM   3932 C  CA  . ALA B 2 189 ? -27.755 -2.978  -12.843 1   36.46  ? 359 ALA B CA  1 
ATOM   3933 C  C   . ALA B 2 189 ? -27.318 -4.021  -13.879 1   36.47  ? 359 ALA B C   1 
ATOM   3934 O  O   . ALA B 2 189 ? -26.866 -3.677  -14.973 1   34.81  ? 359 ALA B O   1 
ATOM   3935 C  CB  . ALA B 2 189 ? -26.7   -2.704  -11.799 1   35.53  ? 359 ALA B CB  1 
ATOM   3936 N  N   . PHE B 2 190 ? -27.502 -5.304  -13.536 1   35.22  ? 360 PHE B N   1 
ATOM   3937 C  CA  . PHE B 2 190 ? -27.056 -6.394  -14.383 1   35.89  ? 360 PHE B CA  1 
ATOM   3938 C  C   . PHE B 2 190 ? -27.904 -6.422  -15.644 1   37.85  ? 360 PHE B C   1 
ATOM   3939 O  O   . PHE B 2 190 ? -27.375 -6.52   -16.751 1   40.34  ? 360 PHE B O   1 
ATOM   3940 C  CB  . PHE B 2 190 ? -27.054 -7.785  -13.749 1   36.52  ? 360 PHE B CB  1 
ATOM   3941 C  CG  . PHE B 2 190 ? -26.595 -8.86   -14.733 1   41.22  ? 360 PHE B CG  1 
ATOM   3942 C  CD1 . PHE B 2 190 ? -25.28  -8.889  -15.207 1   41.64  ? 360 PHE B CD1 1 
ATOM   3943 C  CD2 . PHE B 2 190 ? -27.465 -9.855  -15.17  1   43.07  ? 360 PHE B CD2 1 
ATOM   3944 C  CE1 . PHE B 2 190 ? -24.831 -9.887  -16.075 1   43.73  ? 360 PHE B CE1 1 
ATOM   3945 C  CE2 . PHE B 2 190 ? -27.018 -10.847 -16.038 1   47.83  ? 360 PHE B CE2 1 
ATOM   3946 C  CZ  . PHE B 2 190 ? -25.704 -10.859 -16.501 1   46.71  ? 360 PHE B CZ  1 
ATOM   3947 N  N   . HIS B 2 191 ? -29.224 -6.328  -15.45  1   38.04  ? 361 HIS B N   1 
ATOM   3948 C  CA  . HIS B 2 191 ? -30.165 -6.269  -16.552 1   37.08  ? 361 HIS B CA  1 
ATOM   3949 C  C   . HIS B 2 191 ? -29.871 -5.063  -17.443 1   40.01  ? 361 HIS B C   1 
ATOM   3950 O  O   . HIS B 2 191 ? -29.906 -5.152  -18.675 1   41.1   ? 361 HIS B O   1 
ATOM   3951 C  CB  . HIS B 2 191 ? -31.59  -6.145  -16.032 1   34.8   ? 361 HIS B CB  1 
ATOM   3952 C  CG  . HIS B 2 191 ? -32.538 -5.889  -17.144 1   37.61  ? 361 HIS B CG  1 
ATOM   3953 N  ND1 . HIS B 2 191 ? -32.798 -6.826  -18.123 1   38.96  ? 361 HIS B ND1 1 
ATOM   3954 C  CD2 . HIS B 2 191 ? -33.226 -4.791  -17.481 1   38.07  ? 361 HIS B CD2 1 
ATOM   3955 C  CE1 . HIS B 2 191 ? -33.647 -6.315  -18.993 1   39.93  ? 361 HIS B CE1 1 
ATOM   3956 N  NE2 . HIS B 2 191 ? -33.916 -5.08   -18.624 1   40.16  ? 361 HIS B NE2 1 
ATOM   3957 N  N   . LEU B 2 192 ? -29.596 -3.925  -16.804 1   40.67  ? 362 LEU B N   1 
ATOM   3958 C  CA  . LEU B 2 192 ? -29.504 -2.683  -17.548 1   42.21  ? 362 LEU B CA  1 
ATOM   3959 C  C   . LEU B 2 192 ? -28.228 -2.686  -18.392 1   40.8   ? 362 LEU B C   1 
ATOM   3960 O  O   . LEU B 2 192 ? -28.187 -2.12   -19.493 1   40.4   ? 362 LEU B O   1 
ATOM   3961 C  CB  . LEU B 2 192 ? -29.603 -1.505  -16.582 1   41.8   ? 362 LEU B CB  1 
ATOM   3962 C  CG  . LEU B 2 192 ? -29.654 -0.11   -17.213 1   44.64  ? 362 LEU B CG  1 
ATOM   3963 C  CD1 . LEU B 2 192 ? -30.63  0.002   -18.361 1   45.39  ? 362 LEU B CD1 1 
ATOM   3964 C  CD2 . LEU B 2 192 ? -30.032 0.858   -16.114 1   44.71  ? 362 LEU B CD2 1 
ATOM   3965 N  N   . ALA B 2 193 ? -27.208 -3.373  -17.87  1   38.06  ? 363 ALA B N   1 
ATOM   3966 C  CA  . ALA B 2 193 ? -25.941 -3.413  -18.558 1   39.11  ? 363 ALA B CA  1 
ATOM   3967 C  C   . ALA B 2 193 ? -26.096 -4.343  -19.757 1   41.33  ? 363 ALA B C   1 
ATOM   3968 O  O   . ALA B 2 193 ? -25.727 -3.993  -20.882 1   44.29  ? 363 ALA B O   1 
ATOM   3969 C  CB  . ALA B 2 193 ? -24.863 -3.837  -17.6   1   37.67  ? 363 ALA B CB  1 
ATOM   3970 N  N   . LEU B 2 194 ? -26.745 -5.479  -19.506 1   40.61  ? 364 LEU B N   1 
ATOM   3971 C  CA  . LEU B 2 194 ? -26.978 -6.49   -20.514 1   40.85  ? 364 LEU B CA  1 
ATOM   3972 C  C   . LEU B 2 194 ? -27.783 -5.885  -21.662 1   41.57  ? 364 LEU B C   1 
ATOM   3973 O  O   . LEU B 2 194 ? -27.429 -6.04   -22.834 1   43.3   ? 364 LEU B O   1 
ATOM   3974 C  CB  . LEU B 2 194 ? -27.694 -7.624  -19.786 1   43.54  ? 364 LEU B CB  1 
ATOM   3975 C  CG  . LEU B 2 194 ? -27.891 -8.919  -20.58  1   51.79  ? 364 LEU B CG  1 
ATOM   3976 C  CD1 . LEU B 2 194 ? -26.608 -9.63   -21.049 1   48.65  ? 364 LEU B CD1 1 
ATOM   3977 C  CD2 . LEU B 2 194 ? -28.709 -9.833  -19.708 1   56.53  ? 364 LEU B CD2 1 
ATOM   3978 N  N   . TYR B 2 195 ? -28.859 -5.177  -21.32  1   41.43  ? 365 TYR B N   1 
ATOM   3979 C  CA  . TYR B 2 195 ? -29.723 -4.567  -22.318 1   43.02  ? 365 TYR B CA  1 
ATOM   3980 C  C   . TYR B 2 195 ? -28.939 -3.521  -23.118 1   43.5   ? 365 TYR B C   1 
ATOM   3981 O  O   . TYR B 2 195 ? -28.994 -3.48   -24.345 1   44.23  ? 365 TYR B O   1 
ATOM   3982 C  CB  . TYR B 2 195 ? -31.023 -4.069  -21.669 1   42.49  ? 365 TYR B CB  1 
ATOM   3983 C  CG  . TYR B 2 195 ? -32.01  -3.503  -22.683 1   46.02  ? 365 TYR B CG  1 
ATOM   3984 C  CD1 . TYR B 2 195 ? -32.651 -4.328  -23.615 1   48.76  ? 365 TYR B CD1 1 
ATOM   3985 C  CD2 . TYR B 2 195 ? -32.291 -2.141  -22.731 1   47.21  ? 365 TYR B CD2 1 
ATOM   3986 C  CE1 . TYR B 2 195 ? -33.543 -3.821  -24.55  1   50.26  ? 365 TYR B CE1 1 
ATOM   3987 C  CE2 . TYR B 2 195 ? -33.179 -1.621  -23.661 1   50.61  ? 365 TYR B CE2 1 
ATOM   3988 C  CZ  . TYR B 2 195 ? -33.804 -2.458  -24.575 1   52.49  ? 365 TYR B CZ  1 
ATOM   3989 O  OH  . TYR B 2 195 ? -34.692 -1.91   -25.465 1   55.34  ? 365 TYR B OH  1 
ATOM   3990 N  N   . THR B 2 196 ? -28.194 -2.662  -22.423 1   41.66  ? 366 THR B N   1 
ATOM   3991 C  CA  . THR B 2 196 ? -27.482 -1.606  -23.125 1   41.97  ? 366 THR B CA  1 
ATOM   3992 C  C   . THR B 2 196 ? -26.503 -2.219  -24.122 1   42.35  ? 366 THR B C   1 
ATOM   3993 O  O   . THR B 2 196 ? -26.408 -1.751  -25.231 1   43.95  ? 366 THR B O   1 
ATOM   3994 C  CB  . THR B 2 196 ? -26.759 -0.667  -22.161 1   41.62  ? 366 THR B CB  1 
ATOM   3995 O  OG1 . THR B 2 196 ? -27.685 -0.104  -21.237 1   42.71  ? 366 THR B OG1 1 
ATOM   3996 C  CG2 . THR B 2 196 ? -26.057 0.467   -22.884 1   41.82  ? 366 THR B CG2 1 
ATOM   3997 N  N   . VAL B 2 197 ? -25.788 -3.277  -23.734 1   44.02  ? 367 VAL B N   1 
ATOM   3998 C  CA  . VAL B 2 197 ? -24.638 -3.728  -24.494 1   44.35  ? 367 VAL B CA  1 
ATOM   3999 C  C   . VAL B 2 197 ? -25.044 -4.758  -25.546 1   46.26  ? 367 VAL B C   1 
ATOM   4000 O  O   . VAL B 2 197 ? -24.612 -4.637  -26.698 1   47.96  ? 367 VAL B O   1 
ATOM   4001 C  CB  . VAL B 2 197 ? -23.496 -4.244  -23.604 1   45.05  ? 367 VAL B CB  1 
ATOM   4002 C  CG1 . VAL B 2 197 ? -22.377 -4.832  -24.459 1   47     ? 367 VAL B CG1 1 
ATOM   4003 C  CG2 . VAL B 2 197 ? -22.934 -3.159  -22.69  1   42.66  ? 367 VAL B CG2 1 
ATOM   4004 N  N   . THR B 2 198 ? -25.85  -5.764  -25.148 1   44.84  ? 368 THR B N   1 
ATOM   4005 C  CA  . THR B 2 198 ? -26.152 -6.909  -26.003 1   44.25  ? 368 THR B CA  1 
ATOM   4006 C  C   . THR B 2 198 ? -27.58  -6.866  -26.546 1   46.82  ? 368 THR B C   1 
ATOM   4007 O  O   . THR B 2 198 ? -27.92  -7.64   -27.441 1   48.27  ? 368 THR B O   1 
ATOM   4008 C  CB  . THR B 2 198 ? -25.936 -8.217  -25.243 1   41.74  ? 368 THR B CB  1 
ATOM   4009 O  OG1 . THR B 2 198 ? -26.868 -8.173  -24.168 1   41.29  ? 368 THR B OG1 1 
ATOM   4010 C  CG2 . THR B 2 198 ? -24.52  -8.389  -24.733 1   39.13  ? 368 THR B CG2 1 
ATOM   4011 N  N   . GLY B 2 199 ? -28.438 -6.024  -25.955 1   48.25  ? 369 GLY B N   1 
ATOM   4012 C  CA  . GLY B 2 199 ? -29.849 -6.054  -26.3   1   51.49  ? 369 GLY B CA  1 
ATOM   4013 C  C   . GLY B 2 199 ? -30.652 -7.101  -25.517 1   56.77  ? 369 GLY B C   1 
ATOM   4014 O  O   . GLY B 2 199 ? -31.858 -7.186  -25.717 1   61.04  ? 369 GLY B O   1 
ATOM   4015 N  N   . GLN B 2 200 ? -30.022 -7.885  -24.622 1   53.68  ? 370 GLN B N   1 
ATOM   4016 C  CA  . GLN B 2 200 ? -30.708 -8.997  -23.97  1   55.65  ? 370 GLN B CA  1 
ATOM   4017 C  C   . GLN B 2 200 ? -31.24  -8.576  -22.597 1   53.68  ? 370 GLN B C   1 
ATOM   4018 O  O   . GLN B 2 200 ? -30.985 -7.463  -22.148 1   53.26  ? 370 GLN B O   1 
ATOM   4019 C  CB  . GLN B 2 200 ? -29.77  -10.194 -23.794 1   62.02  ? 370 GLN B CB  1 
ATOM   4020 C  CG  . GLN B 2 200 ? -29.129 -10.67  -25.092 1   70.08  ? 370 GLN B CG  1 
ATOM   4021 C  CD  . GLN B 2 200 ? -28.049 -11.718 -24.922 1   75.06  ? 370 GLN B CD  1 
ATOM   4022 O  OE1 . GLN B 2 200 ? -28.004 -12.686 -25.687 1   91.93  ? 370 GLN B OE1 1 
ATOM   4023 N  NE2 . GLN B 2 200 ? -27.136 -11.52  -23.98  1   65.16  ? 370 GLN B NE2 1 
ATOM   4024 N  N   . SER B 2 201 ? -31.955 -9.49   -21.948 1   50.54  ? 371 SER B N   1 
ATOM   4025 C  CA  . SER B 2 201 ? -32.626 -9.134  -20.678 1   48.25  ? 371 SER B CA  1 
ATOM   4026 C  C   . SER B 2 201 ? -32.355 -10.146 -19.567 1   48.1   ? 371 SER B C   1 
ATOM   4027 O  O   . SER B 2 201 ? -31.806 -11.215 -19.872 1   48.57  ? 371 SER B O   1 
ATOM   4028 C  CB  . SER B 2 201 ? -34.106 -9.011  -20.909 1   48.49  ? 371 SER B CB  1 
ATOM   4029 O  OG  . SER B 2 201 ? -34.421 -7.825  -21.622 1   54.2   ? 371 SER B OG  1 
ATOM   4030 N  N   . TRP B 2 202 ? -32.745 -9.808  -18.337 1   46.45  ? 372 TRP B N   1 
ATOM   4031 C  CA  . TRP B 2 202 ? -32.618 -10.703 -17.165 1   43.22  ? 372 TRP B CA  1 
ATOM   4032 C  C   . TRP B 2 202 ? -32.917 -12.128 -17.575 1   44.4   ? 372 TRP B C   1 
ATOM   4033 O  O   . TRP B 2 202 ? -34.023 -12.397 -18.061 1   46.63  ? 372 TRP B O   1 
ATOM   4034 C  CB  . TRP B 2 202 ? -33.616 -10.224 -16.107 1   42.51  ? 372 TRP B CB  1 
ATOM   4035 C  CG  . TRP B 2 202 ? -33.486 -10.815 -14.729 1   41.92  ? 372 TRP B CG  1 
ATOM   4036 C  CD1 . TRP B 2 202 ? -34.433 -11.543 -14.075 1   41.95  ? 372 TRP B CD1 1 
ATOM   4037 C  CD2 . TRP B 2 202 ? -32.375 -10.688 -13.817 1   39.57  ? 372 TRP B CD2 1 
ATOM   4038 N  NE1 . TRP B 2 202 ? -33.987 -11.897 -12.832 1   40.35  ? 372 TRP B NE1 1 
ATOM   4039 C  CE2 . TRP B 2 202 ? -32.732 -11.386 -12.643 1   39.07  ? 372 TRP B CE2 1 
ATOM   4040 C  CE3 . TRP B 2 202 ? -31.124 -10.068 -13.877 1   39.53  ? 372 TRP B CE3 1 
ATOM   4041 C  CZ2 . TRP B 2 202 ? -31.882 -11.475 -11.546 1   38.25  ? 372 TRP B CZ2 1 
ATOM   4042 C  CZ3 . TRP B 2 202 ? -30.285 -10.16  -12.791 1   36.71  ? 372 TRP B CZ3 1 
ATOM   4043 C  CH2 . TRP B 2 202 ? -30.658 -10.857 -11.645 1   37.52  ? 372 TRP B CH2 1 
ATOM   4044 N  N   . PRO B 2 203 ? -31.966 -13.06  -17.391 1   41.85  ? 373 PRO B N   1 
ATOM   4045 C  CA  . PRO B 2 203 ? -32.187 -14.432 -17.808 1   42.42  ? 373 PRO B CA  1 
ATOM   4046 C  C   . PRO B 2 203 ? -33.054 -15.27  -16.88  1   44.42  ? 373 PRO B C   1 
ATOM   4047 O  O   . PRO B 2 203 ? -33.025 -15.073 -15.662 1   40.75  ? 373 PRO B O   1 
ATOM   4048 C  CB  . PRO B 2 203 ? -30.763 -14.954 -17.891 1   39.26  ? 373 PRO B CB  1 
ATOM   4049 C  CG  . PRO B 2 203 ? -30.003 -14.158 -16.872 1   39.42  ? 373 PRO B CG  1 
ATOM   4050 C  CD  . PRO B 2 203 ? -30.662 -12.799 -16.831 1   38.75  ? 373 PRO B CD  1 
ATOM   4051 N  N   . GLU B 2 204 ? -33.838 -16.175 -17.462 1   47.36  ? 374 GLU B N   1 
ATOM   4052 C  CA  . GLU B 2 204 ? -34.642 -17.112 -16.644 1   50.94  ? 374 GLU B CA  1 
ATOM   4053 C  C   . GLU B 2 204 ? -33.73  -17.709 -15.582 1   44.13  ? 374 GLU B C   1 
ATOM   4054 O  O   . GLU B 2 204 ? -34.192 -17.968 -14.472 1   44.49  ? 374 GLU B O   1 
ATOM   4055 C  CB  . GLU B 2 204 ? -35.19  -18.243 -17.513 1   57.99  ? 374 GLU B CB  1 
ATOM   4056 C  CG  . GLU B 2 204 ? -35.853 -19.371 -16.729 1   65.02  ? 374 GLU B CG  1 
ATOM   4057 C  CD  . GLU B 2 204 ? -37.274 -19.094 -16.275 1   78.5   ? 374 GLU B CD  1 
ATOM   4058 O  OE1 . GLU B 2 204 ? -37.785 -17.977 -16.492 1   77.53  ? 374 GLU B OE1 1 
ATOM   4059 O  OE2 . GLU B 2 204 ? -37.874 -20.016 -15.694 1   91.38  ? 374 GLU B OE2 1 
ATOM   4060 N  N   . SER B 2 205 ? -32.473 -17.92  -15.946 1   42.24  ? 375 SER B N   1 
ATOM   4061 C  CA  . SER B 2 205 ? -31.547 -18.527 -14.989 1   42.54  ? 375 SER B CA  1 
ATOM   4062 C  C   . SER B 2 205 ? -31.488 -17.745 -13.682 1   41.46  ? 375 SER B C   1 
ATOM   4063 O  O   . SER B 2 205 ? -31.309 -18.326 -12.611 1   40.29  ? 375 SER B O   1 
ATOM   4064 C  CB  . SER B 2 205 ? -30.129 -18.534 -15.486 1   41.74  ? 375 SER B CB  1 
ATOM   4065 O  OG  . SER B 2 205 ? -30.055 -19.126 -16.754 1   49.39  ? 375 SER B OG  1 
ATOM   4066 N  N   . LEU B 2 206 ? -31.458 -16.416 -13.802 1   40.49  ? 376 LEU B N   1 
ATOM   4067 C  CA  . LEU B 2 206 ? -31.346 -15.592 -12.613 1   40.82  ? 376 LEU B CA  1 
ATOM   4068 C  C   . LEU B 2 206 ? -32.718 -15.405 -11.965 1   39.2   ? 376 LEU B C   1 
ATOM   4069 O  O   . LEU B 2 206 ? -32.782 -15.132 -10.768 1   43.44  ? 376 LEU B O   1 
ATOM   4070 C  CB  . LEU B 2 206 ? -30.649 -14.292 -12.98  1   38.45  ? 376 LEU B CB  1 
ATOM   4071 C  CG  . LEU B 2 206 ? -29.157 -14.446 -13.252 1   37.18  ? 376 LEU B CG  1 
ATOM   4072 C  CD1 . LEU B 2 206 ? -28.598 -13.145 -13.799 1   36.79  ? 376 LEU B CD1 1 
ATOM   4073 C  CD2 . LEU B 2 206 ? -28.485 -14.869 -11.959 1   35.1   ? 376 LEU B CD2 1 
ATOM   4074 N  N   . VAL B 2 207 ? -33.784 -15.625 -12.745 1   36.14  ? 377 VAL B N   1 
ATOM   4075 C  CA  . VAL B 2 207 ? -35.128 -15.73  -12.215 1   38.8   ? 377 VAL B CA  1 
ATOM   4076 C  C   . VAL B 2 207 ? -35.161 -16.903 -11.235 1   40.74  ? 377 VAL B C   1 
ATOM   4077 O  O   . VAL B 2 207 ? -35.552 -16.732 -10.087 1   40.05  ? 377 VAL B O   1 
ATOM   4078 C  CB  . VAL B 2 207 ? -36.236 -15.844 -13.282 1   41.12  ? 377 VAL B CB  1 
ATOM   4079 C  CG1 . VAL B 2 207 ? -37.624 -15.943 -12.659 1   41.24  ? 377 VAL B CG1 1 
ATOM   4080 C  CG2 . VAL B 2 207 ? -36.186 -14.711 -14.3   1   40.41  ? 377 VAL B CG2 1 
ATOM   4081 N  N   . GLN B 2 208 ? -34.688 -18.076 -11.673 1   42.66  ? 378 GLN B N   1 
ATOM   4082 C  CA  . GLN B 2 208 ? -34.619 -19.262 -10.83  1   42.82  ? 378 GLN B CA  1 
ATOM   4083 C  C   . GLN B 2 208 ? -33.746 -19.01  -9.6    1   41.35  ? 378 GLN B C   1 
ATOM   4084 O  O   . GLN B 2 208 ? -34.092 -19.42  -8.497  1   44.14  ? 378 GLN B O   1 
ATOM   4085 C  CB  . GLN B 2 208 ? -33.897 -20.381 -11.567 1   44.57  ? 378 GLN B CB  1 
ATOM   4086 C  CG  . GLN B 2 208 ? -34.591 -20.819 -12.845 1   46.58  ? 378 GLN B CG  1 
ATOM   4087 C  CD  . GLN B 2 208 ? -35.905 -21.477 -12.53  1   51.7   ? 378 GLN B CD  1 
ATOM   4088 O  OE1 . GLN B 2 208 ? -36.757 -21.631 -13.407 1   57.45  ? 378 GLN B OE1 1 
ATOM   4089 N  NE2 . GLN B 2 208 ? -36.083 -21.854 -11.269 1   52.22  ? 378 GLN B NE2 1 
ATOM   4090 N  N   . LYS B 2 209 ? -32.598 -18.361 -9.782  1   38.84  ? 379 LYS B N   1 
ATOM   4091 C  CA  . LYS B 2 209 ? -31.664 -18.236 -8.677  1   40.03  ? 379 LYS B CA  1 
ATOM   4092 C  C   . LYS B 2 209 ? -32.233 -17.289 -7.617  1   39.35  ? 379 LYS B C   1 
ATOM   4093 O  O   . LYS B 2 209 ? -32.151 -17.617 -6.434  1   37.68  ? 379 LYS B O   1 
ATOM   4094 C  CB  . LYS B 2 209 ? -30.31  -17.728 -9.181  1   40.43  ? 379 LYS B CB  1 
ATOM   4095 C  CG  . LYS B 2 209 ? -29.215 -17.613 -8.124  1   42.78  ? 379 LYS B CG  1 
ATOM   4096 C  CD  . LYS B 2 209 ? -28.069 -16.705 -8.578  1   45.64  ? 379 LYS B CD  1 
ATOM   4097 C  CE  . LYS B 2 209 ? -26.923 -16.679 -7.614  1   47.38  ? 379 LYS B CE  1 
ATOM   4098 N  NZ  . LYS B 2 209 ? -26.486 -18.042 -7.27   1   49.32  ? 379 LYS B NZ  1 
ATOM   4099 N  N   . THR B 2 210 ? -32.811 -16.146 -8.066  1   35.75  ? 380 THR B N   1 
ATOM   4100 C  CA  . THR B 2 210 ? -33.055 -14.99  -7.209  1   34.65  ? 380 THR B CA  1 
ATOM   4101 C  C   . THR B 2 210 ? -34.528 -14.92  -6.832  1   35.13  ? 380 THR B C   1 
ATOM   4102 O  O   . THR B 2 210 ? -34.886 -14.297 -5.831  1   36.33  ? 380 THR B O   1 
ATOM   4103 C  CB  . THR B 2 210 ? -32.621 -13.654 -7.84   1   33.87  ? 380 THR B CB  1 
ATOM   4104 O  OG1 . THR B 2 210 ? -33.422 -13.302 -8.976  1   36.43  ? 380 THR B OG1 1 
ATOM   4105 C  CG2 . THR B 2 210 ? -31.186 -13.67  -8.313  1   32.65  ? 380 THR B CG2 1 
ATOM   4106 N  N   . GLY B 2 211 ? -35.365 -15.455 -7.719  1   35.84  ? 381 GLY B N   1 
ATOM   4107 C  CA  . GLY B 2 211 ? -36.803 -15.265 -7.654  1   36.01  ? 381 GLY B CA  1 
ATOM   4108 C  C   . GLY B 2 211 ? -37.23  -13.881 -8.128  1   35.3   ? 381 GLY B C   1 
ATOM   4109 O  O   . GLY B 2 211 ? -38.412 -13.564 -8.111  1   36.61  ? 381 GLY B O   1 
ATOM   4110 N  N   . TYR B 2 212 ? -36.283 -13.055 -8.57   1   35.4   ? 382 TYR B N   1 
ATOM   4111 C  CA  . TYR B 2 212 ? -36.662 -11.761 -9.124  1   36.54  ? 382 TYR B CA  1 
ATOM   4112 C  C   . TYR B 2 212 ? -37.035 -11.884 -10.599 1   39.43  ? 382 TYR B C   1 
ATOM   4113 O  O   . TYR B 2 212 ? -36.306 -12.52  -11.365 1   37.44  ? 382 TYR B O   1 
ATOM   4114 C  CB  . TYR B 2 212 ? -35.504 -10.774 -9.04   1   34.08  ? 382 TYR B CB  1 
ATOM   4115 C  CG  . TYR B 2 212 ? -34.999 -10.53  -7.627  1   34.13  ? 382 TYR B CG  1 
ATOM   4116 C  CD1 . TYR B 2 212 ? -35.819 -10.74  -6.508  1   35.24  ? 382 TYR B CD1 1 
ATOM   4117 C  CD2 . TYR B 2 212 ? -33.7   -10.086 -7.42   1   31.96  ? 382 TYR B CD2 1 
ATOM   4118 C  CE1 . TYR B 2 212 ? -35.349 -10.494 -5.228  1   33.02  ? 382 TYR B CE1 1 
ATOM   4119 C  CE2 . TYR B 2 212 ? -33.216 -9.879  -6.142  1   32.3   ? 382 TYR B CE2 1 
ATOM   4120 C  CZ  . TYR B 2 212 ? -34.035 -10.096 -5.047  1   32.9   ? 382 TYR B CZ  1 
ATOM   4121 O  OH  . TYR B 2 212 ? -33.491 -9.823  -3.826  1   35.09  ? 382 TYR B OH  1 
ATOM   4122 N  N   . THR B 2 213 ? -38.159 -11.248 -10.978 1   43.47  ? 383 THR B N   1 
ATOM   4123 C  CA  . THR B 2 213 ? -38.518 -11.044 -12.381 1   46.93  ? 383 THR B CA  1 
ATOM   4124 C  C   . THR B 2 213 ? -38.328 -9.577  -12.796 1   46.96  ? 383 THR B C   1 
ATOM   4125 O  O   . THR B 2 213 ? -38.256 -8.675  -11.961 1   46.93  ? 383 THR B O   1 
ATOM   4126 C  CB  . THR B 2 213 ? -39.974 -11.453 -12.593 1   49.11  ? 383 THR B CB  1 
ATOM   4127 O  OG1 . THR B 2 213 ? -40.646 -10.529 -11.738 1   54.29  ? 383 THR B OG1 1 
ATOM   4128 C  CG2 . THR B 2 213 ? -40.257 -12.902 -12.239 1   47.86  ? 383 THR B CG2 1 
ATOM   4129 N  N   . LEU B 2 214 ? -38.327 -9.325  -14.111 1   49.62  ? 384 LEU B N   1 
ATOM   4130 C  CA  . LEU B 2 214 ? -38.318 -7.955  -14.599 1   49.98  ? 384 LEU B CA  1 
ATOM   4131 C  C   . LEU B 2 214 ? -39.427 -7.139  -13.94  1   52.12  ? 384 LEU B C   1 
ATOM   4132 O  O   . LEU B 2 214 ? -39.284 -5.938  -13.761 1   54.54  ? 384 LEU B O   1 
ATOM   4133 C  CB  . LEU B 2 214 ? -38.419 -7.893  -16.117 1   48.28  ? 384 LEU B CB  1 
ATOM   4134 C  CG  . LEU B 2 214 ? -37.114 -8.042  -16.888 1   47.08  ? 384 LEU B CG  1 
ATOM   4135 C  CD1 . LEU B 2 214 ? -37.366 -7.76   -18.348 1   45.39  ? 384 LEU B CD1 1 
ATOM   4136 C  CD2 . LEU B 2 214 ? -36.039 -7.111  -16.315 1   44.98  ? 384 LEU B CD2 1 
ATOM   4137 N  N   . GLU B 2 215 ? -40.546 -7.788  -13.619 1   55.69  ? 385 GLU B N   1 
ATOM   4138 C  CA  . GLU B 2 215 ? -41.645 -7.114  -12.939 1   59.49  ? 385 GLU B CA  1 
ATOM   4139 C  C   . GLU B 2 215 ? -41.205 -6.681  -11.54  1   57.29  ? 385 GLU B C   1 
ATOM   4140 O  O   . GLU B 2 215 ? -41.466 -5.55   -11.147 1   58.82  ? 385 GLU B O   1 
ATOM   4141 C  CB  . GLU B 2 215 ? -42.895 -7.994  -12.883 1   65.92  ? 385 GLU B CB  1 
ATOM   4142 C  CG  . GLU B 2 215 ? -43.286 -8.575  -14.239 1   75.01  ? 385 GLU B CG  1 
ATOM   4143 C  CD  . GLU B 2 215 ? -44.791 -8.78   -14.341 1   87.89  ? 385 GLU B CD  1 
ATOM   4144 O  OE1 . GLU B 2 215 ? -45.394 -8.953  -13.246 1   86.96  ? 385 GLU B OE1 1 
ATOM   4145 O  OE2 . GLU B 2 215 ? -45.351 -8.716  -15.479 1   87.36  ? 385 GLU B OE2 1 
ATOM   4146 N  N   . THR B 2 216 ? -40.551 -7.591  -10.799 1   52.94  ? 386 THR B N   1 
ATOM   4147 C  CA  . THR B 2 216 ? -40.041 -7.326  -9.461  1   52.66  ? 386 THR B CA  1 
ATOM   4148 C  C   . THR B 2 216 ? -39.078 -6.153  -9.538  1   52.69  ? 386 THR B C   1 
ATOM   4149 O  O   . THR B 2 216 ? -39.129 -5.292  -8.661  1   56.56  ? 386 THR B O   1 
ATOM   4150 C  CB  . THR B 2 216 ? -39.316 -8.548  -8.886  1   50.94  ? 386 THR B CB  1 
ATOM   4151 O  OG1 . THR B 2 216 ? -40.354 -9.513  -8.797  1   55.54  ? 386 THR B OG1 1 
ATOM   4152 C  CG2 . THR B 2 216 ? -38.674 -8.303  -7.527  1   48.41  ? 386 THR B CG2 1 
ATOM   4153 N  N   . LEU B 2 217 ? -38.214 -6.155  -10.576 1   48.61  ? 387 LEU B N   1 
ATOM   4154 C  CA  . LEU B 2 217 ? -37.083 -5.235  -10.681 1   45.13  ? 387 LEU B CA  1 
ATOM   4155 C  C   . LEU B 2 217 ? -37.49  -3.861  -11.215 1   45.22  ? 387 LEU B C   1 
ATOM   4156 O  O   . LEU B 2 217 ? -36.749 -2.895  -11.028 1   45.47  ? 387 LEU B O   1 
ATOM   4157 C  CB  . LEU B 2 217 ? -36.02  -5.851  -11.58  1   41.7   ? 387 LEU B CB  1 
ATOM   4158 C  CG  . LEU B 2 217 ? -35.448 -7.155  -11.043 1   39.99  ? 387 LEU B CG  1 
ATOM   4159 C  CD1 . LEU B 2 217 ? -34.517 -7.695  -12.095 1   40.71  ? 387 LEU B CD1 1 
ATOM   4160 C  CD2 . LEU B 2 217 ? -34.726 -6.919  -9.709  1   38.08  ? 387 LEU B CD2 1 
ATOM   4161 N  N   . LYS B 2 218 ? -38.665 -3.787  -11.85  1   45.3   ? 388 LYS B N   1 
ATOM   4162 C  CA  . LYS B 2 218 ? -39.141 -2.599  -12.548 1   49.26  ? 388 LYS B CA  1 
ATOM   4163 C  C   . LYS B 2 218 ? -38.897 -1.327  -11.726 1   51.41  ? 388 LYS B C   1 
ATOM   4164 O  O   . LYS B 2 218 ? -38.286 -0.392  -12.238 1   52.67  ? 388 LYS B O   1 
ATOM   4165 C  CB  . LYS B 2 218 ? -40.591 -2.763  -13.018 1   47.64  ? 388 LYS B CB  1 
ATOM   4166 C  CG  . LYS B 2 218 ? -41.03  -1.9    -14.188 1   50.45  ? 388 LYS B CG  1 
ATOM   4167 C  CD  . LYS B 2 218 ? -42.543 -1.76   -14.277 1   54.24  ? 388 LYS B CD  1 
ATOM   4168 C  CE  . LYS B 2 218 ? -42.919 -0.551  -15.076 1   58.56  ? 388 LYS B CE  1 
ATOM   4169 N  NZ  . LYS B 2 218 ? -44.327 -0.513  -15.466 1   59.07  ? 388 LYS B NZ  1 
ATOM   4170 N  N   . PRO B 2 219 ? -39.365 -1.196  -10.458 1   52.5   ? 389 PRO B N   1 
ATOM   4171 C  CA  . PRO B 2 219 ? -39.22  0.074   -9.735  1   51.53  ? 389 PRO B CA  1 
ATOM   4172 C  C   . PRO B 2 219 ? -37.761 0.507   -9.587  1   50.69  ? 389 PRO B C   1 
ATOM   4173 O  O   . PRO B 2 219 ? -37.431 1.686   -9.709  1   48.84  ? 389 PRO B O   1 
ATOM   4174 C  CB  . PRO B 2 219 ? -39.898 -0.219  -8.389  1   49.17  ? 389 PRO B CB  1 
ATOM   4175 C  CG  . PRO B 2 219 ? -40.902 -1.302  -8.738  1   49.33  ? 389 PRO B CG  1 
ATOM   4176 C  CD  . PRO B 2 219 ? -40.098 -2.203  -9.675  1   51.09  ? 389 PRO B CD  1 
ATOM   4177 N  N   . CYS B 2 220 ? -36.881 -0.458  -9.322  1   50.83  ? 390 CYS B N   1 
ATOM   4178 C  CA  . CYS B 2 220 ? -35.465 -0.151  -9.216  1   48.21  ? 390 CYS B CA  1 
ATOM   4179 C  C   . CYS B 2 220 ? -34.886 0.143   -10.603 1   48.02  ? 390 CYS B C   1 
ATOM   4180 O  O   . CYS B 2 220 ? -34.033 1.019   -10.746 1   46.71  ? 390 CYS B O   1 
ATOM   4181 C  CB  . CYS B 2 220 ? -34.741 -1.292  -8.526  1   46     ? 390 CYS B CB  1 
ATOM   4182 S  SG  . CYS B 2 220 ? -33.01  -0.923  -8.156  1   44.23  ? 390 CYS B SG  1 
ATOM   4183 N  N   . LEU B 2 221 ? -35.352 -0.585  -11.625 1   47.3   ? 391 LEU B N   1 
ATOM   4184 C  CA  . LEU B 2 221 ? -34.918 -0.33   -12.991 1   47.91  ? 391 LEU B CA  1 
ATOM   4185 C  C   . LEU B 2 221 ? -35.267 1.087   -13.44  1   46.86  ? 391 LEU B C   1 
ATOM   4186 O  O   . LEU B 2 221 ? -34.431 1.761   -14.038 1   47.34  ? 391 LEU B O   1 
ATOM   4187 C  CB  . LEU B 2 221 ? -35.487 -1.362  -13.954 1   51.93  ? 391 LEU B CB  1 
ATOM   4188 C  CG  . LEU B 2 221 ? -34.616 -2.595  -14.169 1   57.88  ? 391 LEU B CG  1 
ATOM   4189 C  CD1 . LEU B 2 221 ? -35.44  -3.605  -14.935 1   60.16  ? 391 LEU B CD1 1 
ATOM   4190 C  CD2 . LEU B 2 221 ? -33.339 -2.231  -14.916 1   56.91  ? 391 LEU B CD2 1 
ATOM   4191 N  N   . LEU B 2 222 ? -36.507 1.521   -13.19  1   46.84  ? 392 LEU B N   1 
ATOM   4192 C  CA  . LEU B 2 222 ? -36.943 2.851   -13.599 1   49.17  ? 392 LEU B CA  1 
ATOM   4193 C  C   . LEU B 2 222 ? -36.002 3.916   -13.026 1   49.68  ? 392 LEU B C   1 
ATOM   4194 O  O   . LEU B 2 222 ? -35.653 4.884   -13.704 1   52.84  ? 392 LEU B O   1 
ATOM   4195 C  CB  . LEU B 2 222 ? -38.403 3.124   -13.241 1   47.85  ? 392 LEU B CB  1 
ATOM   4196 C  CG  . LEU B 2 222 ? -39.441 2.321   -14.034 1   51.14  ? 392 LEU B CG  1 
ATOM   4197 C  CD1 . LEU B 2 222 ? -40.846 2.894   -13.958 1   51.13  ? 392 LEU B CD1 1 
ATOM   4198 C  CD2 . LEU B 2 222 ? -39.033 2.159   -15.482 1   51.81  ? 392 LEU B CD2 1 
ATOM   4199 N  N   . ASP B 2 223 ? -35.592 3.713   -11.773 1   46.07  ? 393 ASP B N   1 
ATOM   4200 C  CA  . ASP B 2 223 ? -34.758 4.665   -11.074 1   46.82  ? 393 ASP B CA  1 
ATOM   4201 C  C   . ASP B 2 223 ? -33.352 4.599   -11.653 1   45.71  ? 393 ASP B C   1 
ATOM   4202 O  O   . ASP B 2 223 ? -32.764 5.624   -11.961 1   44.5   ? 393 ASP B O   1 
ATOM   4203 C  CB  . ASP B 2 223 ? -34.734 4.398   -9.575  1   48.73  ? 393 ASP B CB  1 
ATOM   4204 C  CG  . ASP B 2 223 ? -35.913 4.924   -8.765  1   53.61  ? 393 ASP B CG  1 
ATOM   4205 O  OD1 . ASP B 2 223 ? -36.521 5.952   -9.182  1   56.73  ? 393 ASP B OD1 1 
ATOM   4206 O  OD2 . ASP B 2 223 ? -36.23  4.28    -7.73   1   52.46  ? 393 ASP B OD2 1 
ATOM   4207 N  N   . LEU B 2 224 ? -32.8   3.386   -11.754 1   45.03  ? 394 LEU B N   1 
ATOM   4208 C  CA  . LEU B 2 224 ? -31.408 3.206   -12.138 1   42.69  ? 394 LEU B CA  1 
ATOM   4209 C  C   . LEU B 2 224 ? -31.182 3.682   -13.572 1   43.31  ? 394 LEU B C   1 
ATOM   4210 O  O   . LEU B 2 224 ? -30.15  4.275   -13.867 1   43.04  ? 394 LEU B O   1 
ATOM   4211 C  CB  . LEU B 2 224 ? -30.965 1.762   -11.926 1   41.71  ? 394 LEU B CB  1 
ATOM   4212 C  CG  . LEU B 2 224 ? -29.459 1.507   -12.024 1   40.48  ? 394 LEU B CG  1 
ATOM   4213 C  CD1 . LEU B 2 224 ? -28.696 2.257   -10.954 1   39.32  ? 394 LEU B CD1 1 
ATOM   4214 C  CD2 . LEU B 2 224 ? -29.196 0.019   -11.907 1   38.9   ? 394 LEU B CD2 1 
ATOM   4215 N  N   . HIS B 2 225 ? -32.18  3.489   -14.433 1   43.15  ? 395 HIS B N   1 
ATOM   4216 C  CA  . HIS B 2 225 ? -32.104 3.961   -15.839 1   44.47  ? 395 HIS B CA  1 
ATOM   4217 C  C   . HIS B 2 225 ? -32.062 5.488   -15.878 1   49     ? 395 HIS B C   1 
ATOM   4218 O  O   . HIS B 2 225 ? -31.314 6.053   -16.684 1   50.95  ? 395 HIS B O   1 
ATOM   4219 C  CB  . HIS B 2 225 ? -33.304 3.417   -16.606 1   43.67  ? 395 HIS B CB  1 
ATOM   4220 C  CG  . HIS B 2 225 ? -33.464 3.896   -18.001 1   45.01  ? 395 HIS B CG  1 
ATOM   4221 N  ND1 . HIS B 2 225 ? -32.496 3.742   -18.965 1   45.41  ? 395 HIS B ND1 1 
ATOM   4222 C  CD2 . HIS B 2 225 ? -34.495 4.492   -18.599 1   47.12  ? 395 HIS B CD2 1 
ATOM   4223 C  CE1 . HIS B 2 225 ? -32.942 4.244   -20.102 1   47.55  ? 395 HIS B CE1 1 
ATOM   4224 N  NE2 . HIS B 2 225 ? -34.151 4.706   -19.903 1   48.29  ? 395 HIS B NE2 1 
ATOM   4225 N  N   . GLN B 2 226 ? -32.828 6.126   -15.012 1   52.93  ? 396 GLN B N   1 
ATOM   4226 C  CA  . GLN B 2 226 ? -32.837 7.603   -14.956 1   55.1   ? 396 GLN B CA  1 
ATOM   4227 C  C   . GLN B 2 226 ? -31.443 8.077   -14.517 1   53.05  ? 396 GLN B C   1 
ATOM   4228 O  O   . GLN B 2 226 ? -30.904 8.956   -15.189 1   56.99  ? 396 GLN B O   1 
ATOM   4229 C  CB  . GLN B 2 226 ? -34.057 7.949   -14.103 1   61.5   ? 396 GLN B CB  1 
ATOM   4230 C  CG  . GLN B 2 226 ? -34.107 9.375   -13.579 1   70.22  ? 396 GLN B CG  1 
ATOM   4231 C  CD  . GLN B 2 226 ? -35.507 9.872   -13.3   1   78.88  ? 396 GLN B CD  1 
ATOM   4232 O  OE1 . GLN B 2 226 ? -36.487 9.126   -13.377 1   80.2   ? 396 GLN B OE1 1 
ATOM   4233 N  NE2 . GLN B 2 226 ? -35.612 11.149  -12.966 1   79.03  ? 396 GLN B NE2 1 
ATOM   4234 N  N   . THR B 2 227 ? -30.853 7.46    -13.496 1   49.89  ? 397 THR B N   1 
ATOM   4235 C  CA  . THR B 2 227 ? -29.512 7.84    -13.012 1   48.42  ? 397 THR B CA  1 
ATOM   4236 C  C   . THR B 2 227 ? -28.507 7.721   -14.141 1   47.23  ? 397 THR B C   1 
ATOM   4237 O  O   . THR B 2 227 ? -27.636 8.592   -14.234 1   47.65  ? 397 THR B O   1 
ATOM   4238 C  CB  . THR B 2 227 ? -29.168 6.963   -11.809 1   45.2   ? 397 THR B CB  1 
ATOM   4239 O  OG1 . THR B 2 227 ? -30.12  7.326   -10.817 1   47.04  ? 397 THR B OG1 1 
ATOM   4240 C  CG2 . THR B 2 227 ? -27.757 7.18    -11.297 1   44.61  ? 397 THR B CG2 1 
ATOM   4241 N  N   . TYR B 2 228 ? -28.628 6.692   -14.975 1   45.57  ? 398 TYR B N   1 
ATOM   4242 C  CA  . TYR B 2 228 ? -27.723 6.506   -16.137 1   45.46  ? 398 TYR B CA  1 
ATOM   4243 C  C   . TYR B 2 228 ? -27.899 7.669   -17.113 1   48.71  ? 398 TYR B C   1 
ATOM   4244 O  O   . TYR B 2 228 ? -26.894 8.243   -17.557 1   49.22  ? 398 TYR B O   1 
ATOM   4245 C  CB  . TYR B 2 228 ? -28.067 5.141   -16.733 1   43.52  ? 398 TYR B CB  1 
ATOM   4246 C  CG  . TYR B 2 228 ? -27.08  4.532   -17.716 1   45.16  ? 398 TYR B CG  1 
ATOM   4247 C  CD1 . TYR B 2 228 ? -25.839 5.107   -17.944 1   45.01  ? 398 TYR B CD1 1 
ATOM   4248 C  CD2 . TYR B 2 228 ? -27.394 3.369   -18.405 1   45.84  ? 398 TYR B CD2 1 
ATOM   4249 C  CE1 . TYR B 2 228 ? -24.945 4.55    -18.839 1   46.05  ? 398 TYR B CE1 1 
ATOM   4250 C  CE2 . TYR B 2 228 ? -26.505 2.799   -19.3   1   47.89  ? 398 TYR B CE2 1 
ATOM   4251 C  CZ  . TYR B 2 228 ? -25.278 3.395   -19.519 1   49.43  ? 398 TYR B CZ  1 
ATOM   4252 O  OH  . TYR B 2 228 ? -24.4   2.844   -20.403 1   54.21  ? 398 TYR B OH  1 
ATOM   4253 N  N   . LEU B 2 229 ? -29.145 8.003   -17.444 1   48.42  ? 399 LEU B N   1 
ATOM   4254 C  CA  . LEU B 2 229 ? -29.43  9.1     -18.401 1   51.16  ? 399 LEU B CA  1 
ATOM   4255 C  C   . LEU B 2 229 ? -28.935 10.445  -17.838 1   53.08  ? 399 LEU B C   1 
ATOM   4256 O  O   . LEU B 2 229 ? -28.52  11.287  -18.65  1   55.39  ? 399 LEU B O   1 
ATOM   4257 C  CB  . LEU B 2 229 ? -30.921 9.128   -18.726 1   50.93  ? 399 LEU B CB  1 
ATOM   4258 C  CG  . LEU B 2 229 ? -31.488 7.891   -19.423 1   52.76  ? 399 LEU B CG  1 
ATOM   4259 C  CD1 . LEU B 2 229 ? -32.986 7.871   -19.212 1   54.69  ? 399 LEU B CD1 1 
ATOM   4260 C  CD2 . LEU B 2 229 ? -31.161 7.904   -20.901 1   50.19  ? 399 LEU B CD2 1 
ATOM   4261 N  N   . ARG B 2 230 ? -28.931 10.606  -16.52  1   52.51  ? 400 ARG B N   1 
ATOM   4262 C  CA  . ARG B 2 230 ? -28.555 11.907  -15.921 1   60.17  ? 400 ARG B CA  1 
ATOM   4263 C  C   . ARG B 2 230 ? -27.102 11.883  -15.429 1   53.88  ? 400 ARG B C   1 
ATOM   4264 O  O   . ARG B 2 230 ? -26.63  12.933  -14.973 1   51.94  ? 400 ARG B O   1 
ATOM   4265 C  CB  . ARG B 2 230 ? -29.581 12.187  -14.819 1   67.4   ? 400 ARG B CB  1 
ATOM   4266 C  CG  . ARG B 2 230 ? -31.009 12.156  -15.339 1   78.56  ? 400 ARG B CG  1 
ATOM   4267 C  CD  . ARG B 2 230 ? -31.989 12.779  -14.367 1   91.73  ? 400 ARG B CD  1 
ATOM   4268 N  NE  . ARG B 2 230 ? -33.371 12.68   -14.847 1   114.61 ? 400 ARG B NE  1 
ATOM   4269 C  CZ  . ARG B 2 230 ? -34.355 13.48   -14.459 1   120.7  ? 400 ARG B CZ  1 
ATOM   4270 N  NH1 . ARG B 2 230 ? -35.506 13.478  -15.108 1   121.68 ? 400 ARG B NH1 1 
ATOM   4271 N  NH2 . ARG B 2 230 ? -34.191 14.269  -13.413 1   119.29 ? 400 ARG B NH2 1 
ATOM   4272 N  N   . ALA B 2 231 ? -26.425 10.739  -15.541 1   50.29  ? 401 ALA B N   1 
ATOM   4273 C  CA  . ALA B 2 231 ? -25.063 10.608  -15.039 1   48.04  ? 401 ALA B CA  1 
ATOM   4274 C  C   . ALA B 2 231 ? -24.192 11.782  -15.501 1   49.55  ? 401 ALA B C   1 
ATOM   4275 O  O   . ALA B 2 231 ? -23.562 12.435  -14.668 1   52.11  ? 401 ALA B O   1 
ATOM   4276 C  CB  . ALA B 2 231 ? -24.472 9.262   -15.385 1   44.93  ? 401 ALA B CB  1 
ATOM   4277 N  N   . PRO B 2 232 ? -24.151 12.145  -16.809 1   49.28  ? 402 PRO B N   1 
ATOM   4278 C  CA  . PRO B 2 232 ? -23.302 13.259  -17.246 1   50.61  ? 402 PRO B CA  1 
ATOM   4279 C  C   . PRO B 2 232 ? -23.531 14.592  -16.527 1   53.14  ? 402 PRO B C   1 
ATOM   4280 O  O   . PRO B 2 232 ? -22.641 15.443  -16.481 1   54     ? 402 PRO B O   1 
ATOM   4281 C  CB  . PRO B 2 232 ? -23.567 13.362  -18.764 1   50.01  ? 402 PRO B CB  1 
ATOM   4282 C  CG  . PRO B 2 232 ? -24.114 12.014  -19.154 1   49.59  ? 402 PRO B CG  1 
ATOM   4283 C  CD  . PRO B 2 232 ? -24.87  11.5    -17.925 1   48.46  ? 402 PRO B CD  1 
ATOM   4284 N  N   . GLN B 2 233 ? -24.738 14.789  -15.984 1   53.71  ? 403 GLN B N   1 
ATOM   4285 C  CA  . GLN B 2 233 ? -25.092 16.088  -15.431 1   55.62  ? 403 GLN B CA  1 
ATOM   4286 C  C   . GLN B 2 233 ? -25.073 16.063  -13.909 1   54.64  ? 403 GLN B C   1 
ATOM   4287 O  O   . GLN B 2 233 ? -25.288 17.1    -13.296 1   58.31  ? 403 GLN B O   1 
ATOM   4288 C  CB  . GLN B 2 233 ? -26.497 16.571  -15.78  1   58.32  ? 403 GLN B CB  1 
ATOM   4289 C  CG  . GLN B 2 233 ? -26.587 17.338  -17.09  1   67.16  ? 403 GLN B CG  1 
ATOM   4290 C  CD  . GLN B 2 233 ? -26.186 16.518  -18.296 1   72.93  ? 403 GLN B CD  1 
ATOM   4291 O  OE1 . GLN B 2 233 ? -25.394 16.966  -19.134 1   82.24  ? 403 GLN B OE1 1 
ATOM   4292 N  NE2 . GLN B 2 233 ? -26.753 15.324  -18.421 1   72.85  ? 403 GLN B NE2 1 
ATOM   4293 N  N   . HIS B 2 234 ? -24.833 14.9    -13.297 1   50.32  ? 404 HIS B N   1 
ATOM   4294 C  CA  . HIS B 2 234 ? -24.761 14.825  -11.848 1   48.3   ? 404 HIS B CA  1 
ATOM   4295 C  C   . HIS B 2 234 ? -23.657 15.75   -11.31  1   47.89  ? 404 HIS B C   1 
ATOM   4296 O  O   . HIS B 2 234 ? -22.613 15.917  -11.936 1   47.07  ? 404 HIS B O   1 
ATOM   4297 C  CB  . HIS B 2 234 ? -24.598 13.36   -11.453 1   46.61  ? 404 HIS B CB  1 
ATOM   4298 C  CG  . HIS B 2 234 ? -24.988 13.085  -10.045 1   48.64  ? 404 HIS B CG  1 
ATOM   4299 N  ND1 . HIS B 2 234 ? -24.33  13.62   -8.956  1   49.74  ? 404 HIS B ND1 1 
ATOM   4300 C  CD2 . HIS B 2 234 ? -25.984 12.334  -9.551  1   47.08  ? 404 HIS B CD2 1 
ATOM   4301 C  CE1 . HIS B 2 234 ? -24.923 13.202  -7.842  1   48.62  ? 404 HIS B CE1 1 
ATOM   4302 N  NE2 . HIS B 2 234 ? -25.927 12.418  -8.184  1   47.06  ? 404 HIS B NE2 1 
ATOM   4303 N  N   . ALA B 2 235 ? -23.873 16.346  -10.132 1   47.18  ? 405 ALA B N   1 
ATOM   4304 C  CA  . ALA B 2 235 ? -22.824 17.148  -9.504  1   48.18  ? 405 ALA B CA  1 
ATOM   4305 C  C   . ALA B 2 235 ? -21.591 16.297  -9.166  1   47.12  ? 405 ALA B C   1 
ATOM   4306 O  O   . ALA B 2 235 ? -20.486 16.824  -9.097  1   49.15  ? 405 ALA B O   1 
ATOM   4307 C  CB  . ALA B 2 235 ? -23.353 17.849  -8.263  1   46.31  ? 405 ALA B CB  1 
ATOM   4308 N  N   . GLN B 2 236 ? -21.775 14.989  -8.965  1   42.36  ? 406 GLN B N   1 
ATOM   4309 C  CA  . GLN B 2 236 ? -20.666 14.102  -8.665  1   42.55  ? 406 GLN B CA  1 
ATOM   4310 C  C   . GLN B 2 236 ? -20.234 13.357  -9.928  1   43.33  ? 406 GLN B C   1 
ATOM   4311 O  O   . GLN B 2 236 ? -21.054 12.672  -10.542 1   42.75  ? 406 GLN B O   1 
ATOM   4312 C  CB  . GLN B 2 236 ? -21.115 13.103  -7.6    1   39.8   ? 406 GLN B CB  1 
ATOM   4313 C  CG  . GLN B 2 236 ? -21.069 13.651  -6.176  1   43.73  ? 406 GLN B CG  1 
ATOM   4314 C  CD  . GLN B 2 236 ? -21.986 14.824  -5.875  1   47.84  ? 406 GLN B CD  1 
ATOM   4315 O  OE1 . GLN B 2 236 ? -23.223 14.711  -5.869  1   49.59  ? 406 GLN B OE1 1 
ATOM   4316 N  NE2 . GLN B 2 236 ? -21.377 15.961  -5.573  1   47.09  ? 406 GLN B NE2 1 
ATOM   4317 N  N   . GLN B 2 237 ? -18.925 13.436  -10.248 1   43.15  ? 407 GLN B N   1 
ATOM   4318 C  CA  . GLN B 2 237 ? -18.364 12.944  -11.497 1   42.09  ? 407 GLN B CA  1 
ATOM   4319 C  C   . GLN B 2 237 ? -17.307 11.843  -11.314 1   42.76  ? 407 GLN B C   1 
ATOM   4320 O  O   . GLN B 2 237 ? -16.922 11.215  -12.295 1   43.6   ? 407 GLN B O   1 
ATOM   4321 C  CB  . GLN B 2 237 ? -17.904 14.133  -12.335 1   43.66  ? 407 GLN B CB  1 
ATOM   4322 C  CG  . GLN B 2 237 ? -19.037 14.874  -13.054 1   46.89  ? 407 GLN B CG  1 
ATOM   4323 C  CD  . GLN B 2 237 ? -19.832 13.993  -13.999 1   46.95  ? 407 GLN B CD  1 
ATOM   4324 O  OE1 . GLN B 2 237 ? -19.234 13.304  -14.824 1   49.81  ? 407 GLN B OE1 1 
ATOM   4325 N  NE2 . GLN B 2 237 ? -21.157 13.955  -13.88  1   43.62  ? 407 GLN B NE2 1 
ATOM   4326 N  N   . SER B 2 238 ? -16.891 11.542  -10.072 1   41.89  ? 408 SER B N   1 
ATOM   4327 C  CA  . SER B 2 238 ? -15.733 10.698  -9.798  1   40.39  ? 408 SER B CA  1 
ATOM   4328 C  C   . SER B 2 238 ? -15.903 9.286   -10.347 1   40.32  ? 408 SER B C   1 
ATOM   4329 O  O   . SER B 2 238 ? -14.939 8.658   -10.769 1   41.89  ? 408 SER B O   1 
ATOM   4330 C  CB  . SER B 2 238 ? -15.439 10.634  -8.327  1   39.65  ? 408 SER B CB  1 
ATOM   4331 O  OG  . SER B 2 238 ? -14.926 11.884  -7.899  1   41.68  ? 408 SER B OG  1 
ATOM   4332 N  N   . ILE B 2 239 ? -17.13  8.776   -10.325 1   39.97  ? 409 ILE B N   1 
ATOM   4333 C  CA  . ILE B 2 239 ? -17.398 7.43    -10.828 1   39.63  ? 409 ILE B CA  1 
ATOM   4334 C  C   . ILE B 2 239 ? -17.326 7.369   -12.357 1   39.65  ? 409 ILE B C   1 
ATOM   4335 O  O   . ILE B 2 239 ? -16.73  6.441   -12.886 1   39.47  ? 409 ILE B O   1 
ATOM   4336 C  CB  . ILE B 2 239 ? -18.708 6.835   -10.26  1   36.27  ? 409 ILE B CB  1 
ATOM   4337 C  CG1 . ILE B 2 239 ? -18.531 6.468   -8.788  1   33.58  ? 409 ILE B CG1 1 
ATOM   4338 C  CG2 . ILE B 2 239 ? -19.187 5.638   -11.079 1   32.79  ? 409 ILE B CG2 1 
ATOM   4339 C  CD1 . ILE B 2 239 ? -19.839 6.404   -8.021  1   32.82  ? 409 ILE B CD1 1 
ATOM   4340 N  N   . ARG B 2 240 ? -17.929 8.327   -13.066 1   39.68  ? 410 ARG B N   1 
ATOM   4341 C  CA  . ARG B 2 240 ? -17.866 8.27    -14.518 1   41.77  ? 410 ARG B CA  1 
ATOM   4342 C  C   . ARG B 2 240 ? -16.42  8.34    -14.991 1   44.8   ? 410 ARG B C   1 
ATOM   4343 O  O   . ARG B 2 240 ? -16.068 7.65    -15.956 1   47     ? 410 ARG B O   1 
ATOM   4344 C  CB  . ARG B 2 240 ? -18.582 9.421   -15.227 1   41.92  ? 410 ARG B CB  1 
ATOM   4345 C  CG  . ARG B 2 240 ? -20.089 9.372   -15.067 1   41.48  ? 410 ARG B CG  1 
ATOM   4346 C  CD  . ARG B 2 240 ? -20.628 10.567  -15.781 1   40.45  ? 410 ARG B CD  1 
ATOM   4347 N  NE  . ARG B 2 240 ? -20.451 10.401  -17.226 1   41.54  ? 410 ARG B NE  1 
ATOM   4348 C  CZ  . ARG B 2 240 ? -20.093 11.358  -18.076 1   42.56  ? 410 ARG B CZ  1 
ATOM   4349 N  NH1 . ARG B 2 240 ? -20.21  11.159  -19.376 1   42.67  ? 410 ARG B NH1 1 
ATOM   4350 N  NH2 . ARG B 2 240 ? -19.689 12.53   -17.627 1   42.28  ? 410 ARG B NH2 1 
ATOM   4351 N  N   . GLU B 2 241 ? -15.631 9.204   -14.32  1   46.31  ? 411 GLU B N   1 
ATOM   4352 C  CA  . GLU B 2 241 ? -14.226 9.459   -14.617 1   50.34  ? 411 GLU B CA  1 
ATOM   4353 C  C   . GLU B 2 241 ? -13.469 8.141   -14.456 1   48.64  ? 411 GLU B C   1 
ATOM   4354 O  O   . GLU B 2 241 ? -12.754 7.712   -15.36  1   51.95  ? 411 GLU B O   1 
ATOM   4355 C  CB  . GLU B 2 241 ? -13.565 10.489  -13.687 1   51.03  ? 411 GLU B CB  1 
ATOM   4356 C  CG  . GLU B 2 241 ? -14.214 11.869  -13.654 1   55.99  ? 411 GLU B CG  1 
ATOM   4357 C  CD  . GLU B 2 241 ? -14.095 12.755  -14.888 1   66.58  ? 411 GLU B CD  1 
ATOM   4358 O  OE1 . GLU B 2 241 ? -13.305 12.428  -15.815 1   68.19  ? 411 GLU B OE1 1 
ATOM   4359 O  OE2 . GLU B 2 241 ? -14.807 13.797  -14.915 1   68.15  ? 411 GLU B OE2 1 
ATOM   4360 N  N   . LYS B 2 242 ? -13.655 7.516   -13.289 1   43.37  ? 412 LYS B N   1 
ATOM   4361 C  CA  . LYS B 2 242 ? -13.088 6.225   -12.977 1   42.81  ? 412 LYS B CA  1 
ATOM   4362 C  C   . LYS B 2 242 ? -13.402 5.229   -14.091 1   43.04  ? 412 LYS B C   1 
ATOM   4363 O  O   . LYS B 2 242 ? -12.517 4.494   -14.535 1   44.3   ? 412 LYS B O   1 
ATOM   4364 C  CB  . LYS B 2 242 ? -13.71  5.721   -11.678 1   39.59  ? 412 LYS B CB  1 
ATOM   4365 C  CG  . LYS B 2 242 ? -13.192 4.389   -11.194 1   39.97  ? 412 LYS B CG  1 
ATOM   4366 C  CD  . LYS B 2 242 ? -13.974 3.875   -9.983  1   42.06  ? 412 LYS B CD  1 
ATOM   4367 C  CE  . LYS B 2 242 ? -13.439 2.649   -9.311  1   38.79  ? 412 LYS B CE  1 
ATOM   4368 N  NZ  . LYS B 2 242 ? -14.417 2.218   -8.321  1   37.72  ? 412 LYS B NZ  1 
ATOM   4369 N  N   . TYR B 2 243 ? -14.662 5.192   -14.532 1   40.85  ? 413 TYR B N   1 
ATOM   4370 C  CA  . TYR B 2 243 ? -15.047 4.177   -15.498 1   42.38  ? 413 TYR B CA  1 
ATOM   4371 C  C   . TYR B 2 243 ? -14.756 4.579   -16.943 1   45.71  ? 413 TYR B C   1 
ATOM   4372 O  O   . TYR B 2 243 ? -15.188 3.865   -17.842 1   48.16  ? 413 TYR B O   1 
ATOM   4373 C  CB  . TYR B 2 243 ? -16.465 3.662   -15.311 1   39.61  ? 413 TYR B CB  1 
ATOM   4374 C  CG  . TYR B 2 243 ? -16.546 2.658   -14.174 1   39.61  ? 413 TYR B CG  1 
ATOM   4375 C  CD1 . TYR B 2 243 ? -16.608 3.088   -12.85  1   38.95  ? 413 TYR B CD1 1 
ATOM   4376 C  CD2 . TYR B 2 243 ? -16.611 1.291   -14.424 1   37.83  ? 413 TYR B CD2 1 
ATOM   4377 C  CE1 . TYR B 2 243 ? -16.704 2.192   -11.8   1   37.23  ? 413 TYR B CE1 1 
ATOM   4378 C  CE2 . TYR B 2 243 ? -16.696 0.388   -13.381 1   37.87  ? 413 TYR B CE2 1 
ATOM   4379 C  CZ  . TYR B 2 243 ? -16.722 0.838   -12.066 1   38.35  ? 413 TYR B CZ  1 
ATOM   4380 O  OH  . TYR B 2 243 ? -16.781 -0.025  -11.004 1   39.28  ? 413 TYR B OH  1 
ATOM   4381 N  N   . LYS B 2 244 ? -14.003 5.666   -17.16  1   46.91  ? 414 LYS B N   1 
ATOM   4382 C  CA  . LYS B 2 244 ? -13.475 5.981   -18.482 1   51.31  ? 414 LYS B CA  1 
ATOM   4383 C  C   . LYS B 2 244 ? -12.253 5.109   -18.774 1   52.13  ? 414 LYS B C   1 
ATOM   4384 O  O   . LYS B 2 244 ? -11.886 4.934   -19.937 1   52.26  ? 414 LYS B O   1 
ATOM   4385 C  CB  . LYS B 2 244 ? -13.033 7.443   -18.636 1   52.26  ? 414 LYS B CB  1 
ATOM   4386 C  CG  . LYS B 2 244 ? -14.103 8.52    -18.661 1   53.92  ? 414 LYS B CG  1 
ATOM   4387 C  CD  . LYS B 2 244 ? -13.411 9.876   -18.748 1   61.24  ? 414 LYS B CD  1 
ATOM   4388 C  CE  . LYS B 2 244 ? -14.258 11.045  -19.171 1   71.14  ? 414 LYS B CE  1 
ATOM   4389 N  NZ  . LYS B 2 244 ? -15.336 11.31   -18.216 1   68.03  ? 414 LYS B NZ  1 
ATOM   4390 N  N   . ASN B 2 245 ? -11.628 4.597   -17.699 1   52.31  ? 415 ASN B N   1 
ATOM   4391 C  CA  . ASN B 2 245 ? -10.365 3.869   -17.725 1   53.32  ? 415 ASN B CA  1 
ATOM   4392 C  C   . ASN B 2 245 ? -10.513 2.559   -18.502 1   53.36  ? 415 ASN B C   1 
ATOM   4393 O  O   . ASN B 2 245 ? -11.515 1.838   -18.386 1   50.72  ? 415 ASN B O   1 
ATOM   4394 C  CB  . ASN B 2 245 ? -9.917  3.519   -16.307 1   56.41  ? 415 ASN B CB  1 
ATOM   4395 C  CG  . ASN B 2 245 ? -8.458  3.137   -16.168 1   59.63  ? 415 ASN B CG  1 
ATOM   4396 O  OD1 . ASN B 2 245 ? -8.097  1.949   -16.171 1   59.29  ? 415 ASN B OD1 1 
ATOM   4397 N  ND2 . ASN B 2 245 ? -7.602  4.134   -16     1   60.57  ? 415 ASN B ND2 1 
ATOM   4398 N  N   . SER B 2 246 ? -9.455  2.222   -19.246 1   53.51  ? 416 SER B N   1 
ATOM   4399 C  CA  . SER B 2 246 ? -9.428  0.974   -19.992 1   54.56  ? 416 SER B CA  1 
ATOM   4400 C  C   . SER B 2 246 ? -9.67   -0.22   -19.065 1   52.78  ? 416 SER B C   1 
ATOM   4401 O  O   . SER B 2 246 ? -10.214 -1.232  -19.492 1   51.4   ? 416 SER B O   1 
ATOM   4402 C  CB  . SER B 2 246 ? -8.14   0.834   -20.746 1   55.94  ? 416 SER B CB  1 
ATOM   4403 O  OG  . SER B 2 246 ? -7.061  0.832   -19.822 1   60.17  ? 416 SER B OG  1 
ATOM   4404 N  N   . LYS B 2 247 ? -9.24   -0.099  -17.801 1   51.38  ? 417 LYS B N   1 
ATOM   4405 C  CA  . LYS B 2 247 ? -9.326  -1.17   -16.824 1   48.77  ? 417 LYS B CA  1 
ATOM   4406 C  C   . LYS B 2 247 ? -10.767 -1.635  -16.734 1   46.9   ? 417 LYS B C   1 
ATOM   4407 O  O   . LYS B 2 247 ? -10.996 -2.806  -16.462 1   48.55  ? 417 LYS B O   1 
ATOM   4408 C  CB  . LYS B 2 247 ? -8.881  -0.667  -15.447 1   50.61  ? 417 LYS B CB  1 
ATOM   4409 C  CG  . LYS B 2 247 ? -9.178  -1.536  -14.236 1   49.08  ? 417 LYS B CG  1 
ATOM   4410 C  CD  . LYS B 2 247 ? -8.212  -1.082  -13.142 1   55.9   ? 417 LYS B CD  1 
ATOM   4411 C  CE  . LYS B 2 247 ? -8.599  -1.49   -11.75  1   58.68  ? 417 LYS B CE  1 
ATOM   4412 N  NZ  . LYS B 2 247 ? -8.91   -2.921  -11.705 1   64.68  ? 417 LYS B NZ  1 
ATOM   4413 N  N   . TYR B 2 248 ? -11.702 -0.698  -16.972 1   44.87  ? 418 TYR B N   1 
ATOM   4414 C  CA  . TYR B 2 248 ? -13.132 -0.942  -16.901 1   41.45  ? 418 TYR B CA  1 
ATOM   4415 C  C   . TYR B 2 248 ? -13.751 -0.752  -18.279 1   41.07  ? 418 TYR B C   1 
ATOM   4416 O  O   . TYR B 2 248 ? -14.907 -0.37   -18.384 1   40.74  ? 418 TYR B O   1 
ATOM   4417 C  CB  . TYR B 2 248 ? -13.802 0.005   -15.903 1   42.13  ? 418 TYR B CB  1 
ATOM   4418 C  CG  . TYR B 2 248 ? -13.21  -0.02   -14.502 1   43.34  ? 418 TYR B CG  1 
ATOM   4419 C  CD1 . TYR B 2 248 ? -13.504 -1.047  -13.605 1   42.28  ? 418 TYR B CD1 1 
ATOM   4420 C  CD2 . TYR B 2 248 ? -12.371 1.006   -14.077 1   44.75  ? 418 TYR B CD2 1 
ATOM   4421 C  CE1 . TYR B 2 248 ? -12.987 -1.06   -12.318 1   43.75  ? 418 TYR B CE1 1 
ATOM   4422 C  CE2 . TYR B 2 248 ? -11.829 0.994   -12.803 1   47.17  ? 418 TYR B CE2 1 
ATOM   4423 C  CZ  . TYR B 2 248 ? -12.137 -0.038  -11.925 1   49.64  ? 418 TYR B CZ  1 
ATOM   4424 O  OH  . TYR B 2 248 ? -11.594 -0.034  -10.67  1   58.19  ? 418 TYR B OH  1 
ATOM   4425 N  N   . HIS B 2 249 ? -12.957 -1.013  -19.321 1   42.12  ? 419 HIS B N   1 
ATOM   4426 C  CA  . HIS B 2 249 ? -13.377 -1.058  -20.714 1   43.54  ? 419 HIS B CA  1 
ATOM   4427 C  C   . HIS B 2 249 ? -14.147 0.195   -21.105 1   43.85  ? 419 HIS B C   1 
ATOM   4428 O  O   . HIS B 2 249 ? -14.967 0.127   -22.005 1   47.02  ? 419 HIS B O   1 
ATOM   4429 C  CB  . HIS B 2 249 ? -14.145 -2.342  -21.062 1   45.78  ? 419 HIS B CB  1 
ATOM   4430 C  CG  . HIS B 2 249 ? -13.543 -3.554  -20.426 1   51.39  ? 419 HIS B CG  1 
ATOM   4431 N  ND1 . HIS B 2 249 ? -13.823 -3.919  -19.111 1   51.65  ? 419 HIS B ND1 1 
ATOM   4432 C  CD2 . HIS B 2 249 ? -12.62  -4.444  -20.893 1   49.37  ? 419 HIS B CD2 1 
ATOM   4433 C  CE1 . HIS B 2 249 ? -13.117 -5.015  -18.808 1   50.08  ? 419 HIS B CE1 1 
ATOM   4434 N  NE2 . HIS B 2 249 ? -12.373 -5.345  -19.871 1   50.99  ? 419 HIS B NE2 1 
ATOM   4435 N  N   . GLY B 2 250 ? -13.835 1.332   -20.472 1   43.93  ? 420 GLY B N   1 
ATOM   4436 C  CA  . GLY B 2 250 ? -14.346 2.646   -20.845 1   43.17  ? 420 GLY B CA  1 
ATOM   4437 C  C   . GLY B 2 250 ? -15.873 2.691   -20.859 1   42.65  ? 420 GLY B C   1 
ATOM   4438 O  O   . GLY B 2 250 ? -16.464 3.443   -21.636 1   43.19  ? 420 GLY B O   1 
ATOM   4439 N  N   . VAL B 2 251 ? -16.515 1.929   -19.962 1   40.22  ? 421 VAL B N   1 
ATOM   4440 C  CA  . VAL B 2 251 ? -17.949 1.755   -20.116 1   41.29  ? 421 VAL B CA  1 
ATOM   4441 C  C   . VAL B 2 251 ? -18.718 3.05    -19.858 1   42.72  ? 421 VAL B C   1 
ATOM   4442 O  O   . VAL B 2 251 ? -19.781 3.232   -20.437 1   44.06  ? 421 VAL B O   1 
ATOM   4443 C  CB  . VAL B 2 251 ? -18.533 0.571   -19.337 1   39.34  ? 421 VAL B CB  1 
ATOM   4444 C  CG1 . VAL B 2 251 ? -17.891 -0.726  -19.806 1   38     ? 421 VAL B CG1 1 
ATOM   4445 C  CG2 . VAL B 2 251 ? -18.404 0.773   -17.826 1   37.42  ? 421 VAL B CG2 1 
ATOM   4446 N  N   . SER B 2 252 ? -18.191 3.955   -19.017 1   43.51  ? 422 SER B N   1 
ATOM   4447 C  CA  . SER B 2 252 ? -18.899 5.203   -18.755 1   42.84  ? 422 SER B CA  1 
ATOM   4448 C  C   . SER B 2 252 ? -19.068 6.016   -20.033 1   44.16  ? 422 SER B C   1 
ATOM   4449 O  O   . SER B 2 252 ? -19.767 7.02    -20.01  1   44.22  ? 422 SER B O   1 
ATOM   4450 C  CB  . SER B 2 252 ? -18.268 6.033   -17.679 1   41.76  ? 422 SER B CB  1 
ATOM   4451 O  OG  . SER B 2 252 ? -16.98  6.472   -18.074 1   45.3   ? 422 SER B OG  1 
ATOM   4452 N  N   . LEU B 2 253 ? -18.454 5.568   -21.136 1   45.94  ? 423 LEU B N   1 
ATOM   4453 C  CA  . LEU B 2 253 ? -18.521 6.316   -22.386 1   48.99  ? 423 LEU B CA  1 
ATOM   4454 C  C   . LEU B 2 253 ? -19.63  5.772   -23.295 1   49.22  ? 423 LEU B C   1 
ATOM   4455 O  O   . LEU B 2 253 ? -19.977 6.413   -24.299 1   49.31  ? 423 LEU B O   1 
ATOM   4456 C  CB  . LEU B 2 253 ? -17.156 6.328   -23.077 1   50.67  ? 423 LEU B CB  1 
ATOM   4457 C  CG  . LEU B 2 253 ? -16.031 7.096   -22.368 1   52.41  ? 423 LEU B CG  1 
ATOM   4458 C  CD1 . LEU B 2 253 ? -14.746 6.728   -23.074 1   53.38  ? 423 LEU B CD1 1 
ATOM   4459 C  CD2 . LEU B 2 253 ? -16.174 8.63    -22.352 1   55.68  ? 423 LEU B CD2 1 
ATOM   4460 N  N   . LEU B 2 254 ? -20.144 4.574   -22.946 1   46.69  ? 424 LEU B N   1 
ATOM   4461 C  CA  . LEU B 2 254 ? -21.23  3.932   -23.669 1   46     ? 424 LEU B CA  1 
ATOM   4462 C  C   . LEU B 2 254 ? -22.459 4.817   -23.489 1   48.89  ? 424 LEU B C   1 
ATOM   4463 O  O   . LEU B 2 254 ? -22.643 5.421   -22.437 1   48.32  ? 424 LEU B O   1 
ATOM   4464 C  CB  . LEU B 2 254 ? -21.463 2.508   -23.159 1   42.23  ? 424 LEU B CB  1 
ATOM   4465 C  CG  . LEU B 2 254 ? -20.378 1.468   -23.479 1   41.19  ? 424 LEU B CG  1 
ATOM   4466 C  CD1 . LEU B 2 254 ? -20.627 0.096   -22.828 1   36.88  ? 424 LEU B CD1 1 
ATOM   4467 C  CD2 . LEU B 2 254 ? -20.202 1.334   -25.005 1   41.37  ? 424 LEU B CD2 1 
ATOM   4468 N  N   . ASN B 2 255 ? -23.274 4.944   -24.541 1   53.61  ? 425 ASN B N   1 
ATOM   4469 C  CA  . ASN B 2 255 ? -24.519 5.7     -24.441 1   55.18  ? 425 ASN B CA  1 
ATOM   4470 C  C   . ASN B 2 255 ? -25.619 4.87    -23.769 1   54.67  ? 425 ASN B C   1 
ATOM   4471 O  O   . ASN B 2 255 ? -25.878 3.719   -24.143 1   53.63  ? 425 ASN B O   1 
ATOM   4472 C  CB  . ASN B 2 255 ? -24.984 6.226   -25.791 1   56.54  ? 425 ASN B CB  1 
ATOM   4473 C  CG  . ASN B 2 255 ? -24.04  7.253   -26.362 1   56.89  ? 425 ASN B CG  1 
ATOM   4474 O  OD1 . ASN B 2 255 ? -23.817 7.251   -27.572 1   59.06  ? 425 ASN B OD1 1 
ATOM   4475 N  ND2 . ASN B 2 255 ? -23.524 8.16    -25.545 1   56.16  ? 425 ASN B ND2 1 
ATOM   4476 N  N   . PRO B 2 256 ? -26.327 5.442   -22.769 1   50.8   ? 426 PRO B N   1 
ATOM   4477 C  CA  . PRO B 2 256 ? -27.474 4.757   -22.171 1   50.5   ? 426 PRO B CA  1 
ATOM   4478 C  C   . PRO B 2 256 ? -28.552 4.575   -23.247 1   52.35  ? 426 PRO B C   1 
ATOM   4479 O  O   . PRO B 2 256 ? -28.639 5.355   -24.2   1   53.4   ? 426 PRO B O   1 
ATOM   4480 C  CB  . PRO B 2 256 ? -27.89  5.709   -21.036 1   47.95  ? 426 PRO B CB  1 
ATOM   4481 C  CG  . PRO B 2 256 ? -27.437 7.059   -21.549 1   49.43  ? 426 PRO B CG  1 
ATOM   4482 C  CD  . PRO B 2 256 ? -26.108 6.79    -22.231 1   49.78  ? 426 PRO B CD  1 
ATOM   4483 N  N   . PRO B 2 257 ? -29.406 3.528   -23.146 1   51.93  ? 427 PRO B N   1 
ATOM   4484 C  CA  . PRO B 2 257 ? -30.472 3.346   -24.129 1   52.16  ? 427 PRO B CA  1 
ATOM   4485 C  C   . PRO B 2 257 ? -31.538 4.382   -23.785 1   53.37  ? 427 PRO B C   1 
ATOM   4486 O  O   . PRO B 2 257 ? -31.65  4.791   -22.631 1   50.57  ? 427 PRO B O   1 
ATOM   4487 C  CB  . PRO B 2 257 ? -30.907 1.887   -23.88  1   51.95  ? 427 PRO B CB  1 
ATOM   4488 C  CG  . PRO B 2 257 ? -30.575 1.616   -22.413 1   48.01  ? 427 PRO B CG  1 
ATOM   4489 C  CD  . PRO B 2 257 ? -29.394 2.5     -22.079 1   47.99  ? 427 PRO B CD  1 
ATOM   4490 N  N   . GLU B 2 258 ? -32.285 4.835   -24.796 1   60.07  ? 428 GLU B N   1 
ATOM   4491 C  CA  . GLU B 2 258 ? -33.303 5.861   -24.587 1   67.15  ? 428 GLU B CA  1 
ATOM   4492 C  C   . GLU B 2 258 ? -34.515 5.3     -23.839 1   66.51  ? 428 GLU B C   1 
ATOM   4493 O  O   . GLU B 2 258 ? -35.101 5.996   -23.015 1   66.85  ? 428 GLU B O   1 
ATOM   4494 C  CB  . GLU B 2 258 ? -33.832 6.477   -25.879 1   70.94  ? 428 GLU B CB  1 
ATOM   4495 C  CG  . GLU B 2 258 ? -32.764 7.069   -26.792 1   80.36  ? 428 GLU B CG  1 
ATOM   4496 C  CD  . GLU B 2 258 ? -33.362 7.495   -28.131 1   95.6   ? 428 GLU B CD  1 
ATOM   4497 O  OE1 . GLU B 2 258 ? -34.617 7.527   -28.271 1   94.5   ? 428 GLU B OE1 1 
ATOM   4498 O  OE2 . GLU B 2 258 ? -32.563 7.786   -29.057 1   104.43 ? 428 GLU B OE2 1 
ATOM   4499 N  N   . THR B 2 259 ? -34.896 4.051   -24.158 1   63.82  ? 429 THR B N   1 
ATOM   4500 C  CA  . THR B 2 259 ? -36.035 3.368   -23.554 1   63.49  ? 429 THR B CA  1 
ATOM   4501 C  C   . THR B 2 259 ? -35.649 1.953   -23.116 1   62.8   ? 429 THR B C   1 
ATOM   4502 O  O   . THR B 2 259 ? -34.713 1.334   -23.639 1   62.67  ? 429 THR B O   1 
ATOM   4503 C  CB  . THR B 2 259 ? -37.226 3.314   -24.519 1   66.16  ? 429 THR B CB  1 
ATOM   4504 O  OG1 . THR B 2 259 ? -36.878 2.49    -25.632 1   65.07  ? 429 THR B OG1 1 
ATOM   4505 C  CG2 . THR B 2 259 ? -37.733 4.681   -24.949 1   65.56  ? 429 THR B CG2 1 
ATOM   4506 N  N   . LEU B 2 260 ? -36.449 1.41    -22.192 1   61.31  ? 430 LEU B N   1 
ATOM   4507 C  CA  . LEU B 2 260 ? -36.169 0.106   -21.615 1   61.23  ? 430 LEU B CA  1 
ATOM   4508 C  C   . LEU B 2 260 ? -37.064 -0.972  -22.226 1   64.56  ? 430 LEU B C   1 
ATOM   4509 O  O   . LEU B 2 260 ? -36.719 -2.153  -22.192 1   59.61  ? 430 LEU B O   1 
ATOM   4510 C  CB  . LEU B 2 260 ? -36.327 0.176   -20.1   1   57.28  ? 430 LEU B CB  1 
ATOM   4511 C  CG  . LEU B 2 260 ? -35.184 0.827   -19.321 1   55.93  ? 430 LEU B CG  1 
ATOM   4512 C  CD1 . LEU B 2 260 ? -35.276 0.354   -17.879 1   55.63  ? 430 LEU B CD1 1 
ATOM   4513 C  CD2 . LEU B 2 260 ? -33.841 0.459   -19.909 1   55.13  ? 430 LEU B CD2 1 
ATOM   4514 N  N   . ASN B 2 261 ? -38.161 -0.548  -22.839 1   71.95  ? 431 ASN B N   1 
ATOM   4515 C  CA  . ASN B 2 261 ? -39.063 -1.513  -23.516 1   81.67  ? 431 ASN B CA  1 
ATOM   4516 C  C   . ASN B 2 261 ? -39.292 -2.688  -22.563 1   83.64  ? 431 ASN B C   1 
ATOM   4517 O  O   . ASN B 2 261 ? -39.059 -3.845  -22.96  1   76.5   ? 431 ASN B O   1 
ATOM   4518 C  CB  . ASN B 2 261 ? -38.521 -1.871  -24.894 1   89.4   ? 431 ASN B CB  1 
ATOM   4519 C  CG  . ASN B 2 261 ? -38.106 -0.643  -25.667 1   95.8   ? 431 ASN B CG  1 
ATOM   4520 O  OD1 . ASN B 2 261 ? -36.917 -0.449  -25.939 1   98.44  ? 431 ASN B OD1 1 
ATOM   4521 N  ND2 . ASN B 2 261 ? -39.065 0.199   -26.021 1   95.37  ? 431 ASN B ND2 1 
ATOM   4522 N  N   . VAL B 2 262 ? -39.726 -2.382  -21.343 1   86.8   ? 432 VAL B N   1 
ATOM   4523 C  CA  . VAL B 2 262 ? -39.985 -3.442  -20.329 1   92.6   ? 432 VAL B CA  1 
ATOM   4524 C  C   . VAL B 2 262 ? -41.452 -3.865  -20.484 1   106.91 ? 432 VAL B C   1 
ATOM   4525 O  O   . VAL B 2 262 ? -42.328 -3.007  -20.27  1   121.02 ? 432 VAL B O   1 
ATOM   4526 C  CB  . VAL B 2 262 ? -39.642 -2.893  -18.931 1   81.96  ? 432 VAL B CB  1 
ATOM   4527 C  CG1 . VAL B 2 262 ? -40.001 -3.889  -17.836 1   71.33  ? 432 VAL B CG1 1 
ATOM   4528 C  CG2 . VAL B 2 262 ? -38.177 -2.495  -18.814 1   81.24  ? 432 VAL B CG2 1 
ATOM   4529 N  N   . HIS B 2 263 ? -41.716 -5.12   -20.855 1   107.2  ? 433 HIS B N   1 
ATOM   4530 C  CA  . HIS B 2 263 ? -43.113 -5.536  -21.165 1   109.59 ? 433 HIS B CA  1 
ATOM   4531 C  C   . HIS B 2 263 ? -43.588 -6.691  -20.288 1   108.26 ? 433 HIS B C   1 
ATOM   4532 O  O   . HIS B 2 263 ? -42.759 -7.365  -19.65  1   119.33 ? 433 HIS B O   1 
ATOM   4533 C  CB  . HIS B 2 263 ? -43.235 -6.032  -22.608 1   113.29 ? 433 HIS B CB  1 
ATOM   4534 C  CG  . HIS B 2 263 ? -42.487 -5.22   -23.612 1   131.04 ? 433 HIS B CG  1 
ATOM   4535 N  ND1 . HIS B 2 263 ? -41.527 -5.763  -24.439 1   134.53 ? 433 HIS B ND1 1 
ATOM   4536 C  CD2 . HIS B 2 263 ? -42.558 -3.922  -23.93  1   137.86 ? 433 HIS B CD2 1 
ATOM   4537 C  CE1 . HIS B 2 263 ? -41.039 -4.814  -25.222 1   136.05 ? 433 HIS B CE1 1 
ATOM   4538 N  NE2 . HIS B 2 263 ? -41.65  -3.687  -24.929 1   133.9  ? 433 HIS B NE2 1 
ATOM   4539 N  N   . HIS B 2 264 ? -44.9   -6.931  -20.296 1   104.17 ? 434 HIS B N   1 
ATOM   4540 C  CA  . HIS B 2 264 ? -45.484 -8.029  -19.489 1   103.2  ? 434 HIS B CA  1 
ATOM   4541 C  C   . HIS B 2 264 ? -45.578 -9.318  -20.301 1   106.06 ? 434 HIS B C   1 
ATOM   4542 O  O   . HIS B 2 264 ? -46.068 -9.288  -21.442 1   104.05 ? 434 HIS B O   1 
ATOM   4543 C  CB  . HIS B 2 264 ? -46.883 -7.656  -18.994 1   103.85 ? 434 HIS B CB  1 
ATOM   4544 C  CG  . HIS B 2 264 ? -47.635 -8.791  -18.384 1   105.29 ? 434 HIS B CG  1 
ATOM   4545 N  ND1 . HIS B 2 264 ? -47.369 -9.266  -17.119 1   106.52 ? 434 HIS B ND1 1 
ATOM   4546 C  CD2 . HIS B 2 264 ? -48.636 -9.542  -18.854 1   102.53 ? 434 HIS B CD2 1 
ATOM   4547 C  CE1 . HIS B 2 264 ? -48.188 -10.269 -16.847 1   101.87 ? 434 HIS B CE1 1 
ATOM   4548 N  NE2 . HIS B 2 264 ? -48.963 -10.455 -17.889 1   102.57 ? 434 HIS B NE2 1 
ATOM   4549 N  N   . HIS B 2 265 ? -45.096 -10.414 -19.73  1   103.92 ? 435 HIS B N   1 
ATOM   4550 C  CA  . HIS B 2 265 ? -45.215 -11.735 -20.334 1   103.47 ? 435 HIS B CA  1 
ATOM   4551 C  C   . HIS B 2 265 ? -46.559 -12.346 -19.914 1   100.87 ? 435 HIS B C   1 
ATOM   4552 O  O   . HIS B 2 265 ? -46.808 -12.504 -18.72  1   97.73  ? 435 HIS B O   1 
ATOM   4553 C  CB  . HIS B 2 265 ? -44.035 -12.621 -19.904 1   101.08 ? 435 HIS B CB  1 
ATOM   4554 C  CG  . HIS B 2 265 ? -42.663 -12.009 -19.911 1   97.89  ? 435 HIS B CG  1 
ATOM   4555 N  ND1 . HIS B 2 265 ? -42.31  -10.869 -20.604 1   101.65 ? 435 HIS B ND1 1 
ATOM   4556 C  CD2 . HIS B 2 265 ? -41.547 -12.411 -19.28  1   92.09  ? 435 HIS B CD2 1 
ATOM   4557 C  CE1 . HIS B 2 265 ? -41.026 -10.598 -20.392 1   99.43  ? 435 HIS B CE1 1 
ATOM   4558 N  NE2 . HIS B 2 265 ? -40.544 -11.529 -19.597 1   96.07  ? 435 HIS B NE2 1 
ATOM   4559 N  N   . HIS B 2 266 ? -47.434 -12.666 -20.881 1   104.07 ? 436 HIS B N   1 
ATOM   4560 C  CA  . HIS B 2 266 ? -48.792 -13.1   -20.567 1   106.23 ? 436 HIS B CA  1 
ATOM   4561 C  C   . HIS B 2 266 ? -48.823 -14.61  -20.312 1   111.79 ? 436 HIS B C   1 
ATOM   4562 O  O   . HIS B 2 266 ? -48.591 -15.402 -21.229 1   126.45 ? 436 HIS B O   1 
ATOM   4563 C  CB  . HIS B 2 266 ? -49.78  -12.701 -21.669 1   101.4  ? 436 HIS B CB  1 
ATOM   4564 C  CG  . HIS B 2 266 ? -49.875 -11.245 -21.986 1   104.94 ? 436 HIS B CG  1 
ATOM   4565 N  ND1 . HIS B 2 266 ? -48.81  -10.369 -21.974 1   103.88 ? 436 HIS B ND1 1 
ATOM   4566 C  CD2 . HIS B 2 266 ? -50.938 -10.523 -22.371 1   109.18 ? 436 HIS B CD2 1 
ATOM   4567 C  CE1 . HIS B 2 266 ? -49.226 -9.156  -22.315 1   105.66 ? 436 HIS B CE1 1 
ATOM   4568 N  NE2 . HIS B 2 266 ? -50.516 -9.23   -22.564 1   109.78 ? 436 HIS B NE2 1 
ATOM   4569 N  N   . HIS B 2 267 ? -49.128 -14.996 -19.06  1   103.58 ? 437 HIS B N   1 
ATOM   4570 C  CA  . HIS B 2 267 ? -49.329 -16.38  -18.644 1   92.18  ? 437 HIS B CA  1 
ATOM   4571 C  C   . HIS B 2 267 ? -48.017 -17.169 -18.687 1   85.57  ? 437 HIS B C   1 
ATOM   4572 O  O   . HIS B 2 267 ? -47.982 -18.265 -19.243 1   83.51  ? 437 HIS B O   1 
ATOM   4573 C  CB  . HIS B 2 267 ? -50.454 -17.029 -19.457 1   92.23  ? 437 HIS B CB  1 
ATOM   4574 C  CG  . HIS B 2 267 ? -51.679 -16.183 -19.64  1   100.29 ? 437 HIS B CG  1 
ATOM   4575 N  ND1 . HIS B 2 267 ? -52.091 -15.691 -20.866 1   107.03 ? 437 HIS B ND1 1 
ATOM   4576 C  CD2 . HIS B 2 267 ? -52.62  -15.795 -18.762 1   100.79 ? 437 HIS B CD2 1 
ATOM   4577 C  CE1 . HIS B 2 267 ? -53.225 -15.009 -20.724 1   105.67 ? 437 HIS B CE1 1 
ATOM   4578 N  NE2 . HIS B 2 267 ? -53.566 -15.066 -19.452 1   104.71 ? 437 HIS B NE2 1 
ATOM   4579 N  N   . HIS B 2 268 ? -46.954 -16.599 -18.088 1   79.3   ? 438 HIS B N   1 
ATOM   4580 C  CA  . HIS B 2 268 ? -45.633 -17.204 -17.932 1   77.13  ? 438 HIS B CA  1 
ATOM   4581 C  C   . HIS B 2 268 ? -45.279 -17.253 -16.434 1   69.47  ? 438 HIS B C   1 
ATOM   4582 O  O   . HIS B 2 268 ? -45.298 -18.401 -15.954 1   63.66  ? 438 HIS B O   1 
ATOM   4583 C  CB  . HIS B 2 268 ? -44.583 -16.493 -18.813 1   78.69  ? 438 HIS B CB  1 
ATOM   4584 C  CG  . HIS B 2 268 ? -43.131 -16.941 -18.759 1   83.29  ? 438 HIS B CG  1 
ATOM   4585 N  ND1 . HIS B 2 268 ? -42.093 -16.065 -19.034 1   82.81  ? 438 HIS B ND1 1 
ATOM   4586 C  CD2 . HIS B 2 268 ? -42.533 -18.122 -18.503 1   83.72  ? 438 HIS B CD2 1 
ATOM   4587 C  CE1 . HIS B 2 268 ? -40.927 -16.685 -18.923 1   82.22  ? 438 HIS B CE1 1 
ATOM   4588 N  NE2 . HIS B 2 268 ? -41.172 -17.936 -18.592 1   86.67  ? 438 HIS B NE2 1 
ATOM   4589 N  N   . SER C 1 4   ? -14.837 4.798   28.378  1   75.13  ? 0   SER C N   1 
ATOM   4590 C  CA  . SER C 1 4   ? -16.307 4.594   28.394  1   77.31  ? 0   SER C CA  1 
ATOM   4591 C  C   . SER C 1 4   ? -16.997 5.919   28.061  1   76.75  ? 0   SER C C   1 
ATOM   4592 O  O   . SER C 1 4   ? -17.803 5.956   27.106  1   68.42  ? 0   SER C O   1 
ATOM   4593 C  CB  . SER C 1 4   ? -16.75  4.067   29.729  1   76.72  ? 0   SER C CB  1 
ATOM   4594 O  OG  . SER C 1 4   ? -16.221 2.771   29.974  1   79.46  ? 0   SER C OG  1 
ATOM   4595 N  N   . MET C 1 5   ? -16.679 6.959   28.827  1   70.83  ? 1   MET C N   1 
ATOM   4596 C  CA  . MET C 1 5   ? -17.26  8.295   28.586  1   66.21  ? 1   MET C CA  1 
ATOM   4597 C  C   . MET C 1 5   ? -16.138 9.195   28.057  1   67.31  ? 1   MET C C   1 
ATOM   4598 O  O   . MET C 1 5   ? -16.269 10.425  28.159  1   65.1   ? 1   MET C O   1 
ATOM   4599 C  CB  . MET C 1 5   ? -17.853 8.812   29.898  1   66.25  ? 1   MET C CB  1 
ATOM   4600 C  CG  . MET C 1 5   ? -18.8   7.836   30.55   1   65.98  ? 1   MET C CG  1 
ATOM   4601 S  SD  . MET C 1 5   ? -20.415 7.958   29.763  1   72.53  ? 1   MET C SD  1 
ATOM   4602 C  CE  . MET C 1 5   ? -20.721 9.692   30.111  1   63.42  ? 1   MET C CE  1 
ATOM   4603 N  N   . GLU C 1 6   ? -15.088 8.589   27.499  1   71.3   ? 2   GLU C N   1 
ATOM   4604 C  CA  . GLU C 1 6   ? -13.923 9.337   26.963  1   71.85  ? 2   GLU C CA  1 
ATOM   4605 C  C   . GLU C 1 6   ? -14.355 10.175  25.764  1   66.77  ? 2   GLU C C   1 
ATOM   4606 O  O   . GLU C 1 6   ? -13.696 11.173  25.485  1   67.03  ? 2   GLU C O   1 
ATOM   4607 C  CB  . GLU C 1 6   ? -12.862 8.319   26.554  1   79.88  ? 2   GLU C CB  1 
ATOM   4608 C  CG  . GLU C 1 6   ? -11.693 8.887   25.753  1   95.75  ? 2   GLU C CG  1 
ATOM   4609 C  CD  . GLU C 1 6   ? -11.198 7.992   24.628  1   107.71 ? 2   GLU C CD  1 
ATOM   4610 O  OE1 . GLU C 1 6   ? -10.505 6.996   24.924  1   106.83 ? 2   GLU C OE1 1 
ATOM   4611 O  OE2 . GLU C 1 6   ? -11.501 8.288   23.453  1   109.49 ? 2   GLU C OE2 1 
ATOM   4612 N  N   . ASN C 1 7   ? -15.406 9.753   25.069  1   61.44  ? 3   ASN C N   1 
ATOM   4613 C  CA  . ASN C 1 7   ? -15.82  10.469  23.837  1   58.4   ? 3   ASN C CA  1 
ATOM   4614 C  C   . ASN C 1 7   ? -16.827 11.549  24.211  1   55.65  ? 3   ASN C C   1 
ATOM   4615 O  O   . ASN C 1 7   ? -17.277 12.267  23.311  1   56.31  ? 3   ASN C O   1 
ATOM   4616 C  CB  . ASN C 1 7   ? -16.4   9.518   22.8    1   57.65  ? 3   ASN C CB  1 
ATOM   4617 C  CG  . ASN C 1 7   ? -15.394 8.506   22.313  1   60.94  ? 3   ASN C CG  1 
ATOM   4618 O  OD1 . ASN C 1 7   ? -14.195 8.796   22.256  1   60.71  ? 3   ASN C OD1 1 
ATOM   4619 N  ND2 . ASN C 1 7   ? -15.859 7.32    21.953  1   58.59  ? 3   ASN C ND2 1 
ATOM   4620 N  N   . PHE C 1 8   ? -17.159 11.646  25.494  1   52.3   ? 4   PHE C N   1 
ATOM   4621 C  CA  . PHE C 1 8   ? -18.195 12.621  25.915  1   50.08  ? 4   PHE C CA  1 
ATOM   4622 C  C   . PHE C 1 8   ? -17.537 13.736  26.701  1   52.43  ? 4   PHE C C   1 
ATOM   4623 O  O   . PHE C 1 8   ? -16.863 13.47   27.7    1   56.34  ? 4   PHE C O   1 
ATOM   4624 C  CB  . PHE C 1 8   ? -19.323 11.892  26.648  1   45.2   ? 4   PHE C CB  1 
ATOM   4625 C  CG  . PHE C 1 8   ? -20.294 11.181  25.72   1   42.86  ? 4   PHE C CG  1 
ATOM   4626 C  CD1 . PHE C 1 8   ? -21.045 11.894  24.797  1   41.65  ? 4   PHE C CD1 1 
ATOM   4627 C  CD2 . PHE C 1 8   ? -20.44  9.801   25.765  1   42.74  ? 4   PHE C CD2 1 
ATOM   4628 C  CE1 . PHE C 1 8   ? -21.925 11.244  23.951  1   41.34  ? 4   PHE C CE1 1 
ATOM   4629 C  CE2 . PHE C 1 8   ? -21.32  9.157   24.914  1   41.09  ? 4   PHE C CE2 1 
ATOM   4630 C  CZ  . PHE C 1 8   ? -22.059 9.88    24.011  1   41.37  ? 4   PHE C CZ  1 
ATOM   4631 N  N   . GLN C 1 9   ? -17.722 14.965  26.233  1   53.9   ? 5   GLN C N   1 
ATOM   4632 C  CA  . GLN C 1 9   ? -17.16  16.145  26.93   1   59.04  ? 5   GLN C CA  1 
ATOM   4633 C  C   . GLN C 1 9   ? -18.302 16.912  27.598  1   57.44  ? 5   GLN C C   1 
ATOM   4634 O  O   . GLN C 1 9   ? -19.215 17.35   26.884  1   56.72  ? 5   GLN C O   1 
ATOM   4635 C  CB  . GLN C 1 9   ? -16.478 17.077  25.935  1   64.42  ? 5   GLN C CB  1 
ATOM   4636 C  CG  . GLN C 1 9   ? -15.762 18.264  26.567  1   71.09  ? 5   GLN C CG  1 
ATOM   4637 C  CD  . GLN C 1 9   ? -14.607 17.851  27.449  1   76.49  ? 5   GLN C CD  1 
ATOM   4638 O  OE1 . GLN C 1 9   ? -13.649 17.211  27      1   78.92  ? 5   GLN C OE1 1 
ATOM   4639 N  NE2 . GLN C 1 9   ? -14.686 18.224  28.717  1   77.95  ? 5   GLN C NE2 1 
ATOM   4640 N  N   . LYS C 1 10  ? -18.25  17.059  28.919  1   58.13  ? 6   LYS C N   1 
ATOM   4641 C  CA  . LYS C 1 10  ? -19.357 17.745  29.572  1   57.48  ? 6   LYS C CA  1 
ATOM   4642 C  C   . LYS C 1 10  ? -19.187 19.251  29.396  1   54.71  ? 6   LYS C C   1 
ATOM   4643 O  O   . LYS C 1 10  ? -18.084 19.726  29.141  1   54.33  ? 6   LYS C O   1 
ATOM   4644 C  CB  . LYS C 1 10  ? -19.646 17.258  30.999  1   63.38  ? 6   LYS C CB  1 
ATOM   4645 C  CG  . LYS C 1 10  ? -18.593 17.548  32.055  1   74.6   ? 6   LYS C CG  1 
ATOM   4646 C  CD  . LYS C 1 10  ? -19.042 17.076  33.439  1   79.39  ? 6   LYS C CD  1 
ATOM   4647 C  CE  . LYS C 1 10  ? -18.079 17.436  34.539  1   85.12  ? 6   LYS C CE  1 
ATOM   4648 N  NZ  . LYS C 1 10  ? -18.417 16.688  35.75   1   87.28  ? 6   LYS C NZ  1 
ATOM   4649 N  N   . VAL C 1 11  ? -20.314 19.965  29.501  1   53.01  ? 7   VAL C N   1 
ATOM   4650 C  CA  . VAL C 1 11  ? -20.47  21.344  29.068  1   54.3   ? 7   VAL C CA  1 
ATOM   4651 C  C   . VAL C 1 11  ? -21.086 22.147  30.211  1   54.71  ? 7   VAL C C   1 
ATOM   4652 O  O   . VAL C 1 11  ? -20.527 23.144  30.652  1   56.52  ? 7   VAL C O   1 
ATOM   4653 C  CB  . VAL C 1 11  ? -21.325 21.417  27.785  1   51.75  ? 7   VAL C CB  1 
ATOM   4654 C  CG1 . VAL C 1 11  ? -21.724 22.847  27.439  1   51     ? 7   VAL C CG1 1 
ATOM   4655 C  CG2 . VAL C 1 11  ? -20.623 20.742  26.606  1   52.01  ? 7   VAL C CG2 1 
ATOM   4656 N  N   . GLU C 1 12  ? -22.237 21.691  30.708  1   53.35  ? 8   GLU C N   1 
ATOM   4657 C  CA  . GLU C 1 12  ? -22.87  22.356  31.831  1   57.84  ? 8   GLU C CA  1 
ATOM   4658 C  C   . GLU C 1 12  ? -23.846 21.389  32.5    1   58.41  ? 8   GLU C C   1 
ATOM   4659 O  O   . GLU C 1 12  ? -24.273 20.417  31.883  1   60.4   ? 8   GLU C O   1 
ATOM   4660 C  CB  . GLU C 1 12  ? -23.482 23.67   31.345  1   59.79  ? 8   GLU C CB  1 
ATOM   4661 C  CG  . GLU C 1 12  ? -24.695 23.451  30.448  1   61.69  ? 8   GLU C CG  1 
ATOM   4662 C  CD  . GLU C 1 12  ? -25.23  24.671  29.727  1   64.44  ? 8   GLU C CD  1 
ATOM   4663 O  OE1 . GLU C 1 12  ? -24.495 25.277  28.909  1   65.22  ? 8   GLU C OE1 1 
ATOM   4664 O  OE2 . GLU C 1 12  ? -26.405 24.997  29.99   1   65.51  ? 8   GLU C OE2 1 
ATOM   4665 N  N   . LYS C 1 13  ? -24.167 21.645  33.775  1   62.57  ? 9   LYS C N   1 
ATOM   4666 C  CA  . LYS C 1 13  ? -25.21  20.9    34.466  1   65.14  ? 9   LYS C CA  1 
ATOM   4667 C  C   . LYS C 1 13  ? -26.556 21.375  33.925  1   62.33  ? 9   LYS C C   1 
ATOM   4668 O  O   . LYS C 1 13  ? -26.743 22.576  33.758  1   68.29  ? 9   LYS C O   1 
ATOM   4669 C  CB  . LYS C 1 13  ? -25.12  21.224  35.962  1   72.44  ? 9   LYS C CB  1 
ATOM   4670 C  CG  . LYS C 1 13  ? -26.092 20.48   36.888  1   82.14  ? 9   LYS C CG  1 
ATOM   4671 C  CD  . LYS C 1 13  ? -26.828 21.453  37.812  1   93.36  ? 9   LYS C CD  1 
ATOM   4672 C  CE  . LYS C 1 13  ? -27.439 20.845  39.035  1   96.73  ? 9   LYS C CE  1 
ATOM   4673 N  NZ  . LYS C 1 13  ? -26.365 20.337  39.893  1   100.54 ? 9   LYS C NZ  1 
ATOM   4674 N  N   . ILE C 1 14  ? -27.487 20.454  33.643  1   55.73  ? 10  ILE C N   1 
ATOM   4675 C  CA  . ILE C 1 14  ? -28.769 20.849  33.078  1   57.16  ? 10  ILE C CA  1 
ATOM   4676 C  C   . ILE C 1 14  ? -29.786 20.97   34.208  1   68.12  ? 10  ILE C C   1 
ATOM   4677 O  O   . ILE C 1 14  ? -30.561 21.92   34.264  1   74.43  ? 10  ILE C O   1 
ATOM   4678 C  CB  . ILE C 1 14  ? -29.286 19.814  32.069  1   53.12  ? 10  ILE C CB  1 
ATOM   4679 C  CG1 . ILE C 1 14  ? -28.533 19.853  30.744  1   50.8   ? 10  ILE C CG1 1 
ATOM   4680 C  CG2 . ILE C 1 14  ? -30.8   19.963  31.87   1   51.35  ? 10  ILE C CG2 1 
ATOM   4681 C  CD1 . ILE C 1 14  ? -29.009 18.797  29.757  1   43.46  ? 10  ILE C CD1 1 
ATOM   4682 N  N   . GLY C 1 15  ? -29.801 19.941  35.057  1   71.7   ? 11  GLY C N   1 
ATOM   4683 C  CA  . GLY C 1 15  ? -30.805 19.719  36.079  1   74.36  ? 11  GLY C CA  1 
ATOM   4684 C  C   . GLY C 1 15  ? -30.243 18.727  37.092  1   77.67  ? 11  GLY C C   1 
ATOM   4685 O  O   . GLY C 1 15  ? -29.045 18.446  37.064  1   73.77  ? 11  GLY C O   1 
ATOM   4686 N  N   . GLU C 1 16  ? -31.097 18.232  37.984  1   84.93  ? 12  GLU C N   1 
ATOM   4687 C  CA  . GLU C 1 16  ? -30.633 17.304  39.038  1   90.63  ? 12  GLU C CA  1 
ATOM   4688 C  C   . GLU C 1 16  ? -31.834 16.639  39.69   1   94.21  ? 12  GLU C C   1 
ATOM   4689 O  O   . GLU C 1 16  ? -32.967 17.095  39.447  1   91.63  ? 12  GLU C O   1 
ATOM   4690 C  CB  . GLU C 1 16  ? -29.955 18.025  40.198  1   91.97  ? 12  GLU C CB  1 
ATOM   4691 C  CG  . GLU C 1 16  ? -28.823 17.222  40.829  1   91.52  ? 12  GLU C CG  1 
ATOM   4692 C  CD  . GLU C 1 16  ? -28.291 17.86   42.095  1   94.52  ? 12  GLU C CD  1 
ATOM   4693 O  OE1 . GLU C 1 16  ? -28.929 18.815  42.575  1   88.39  ? 12  GLU C OE1 1 
ATOM   4694 O  OE2 . GLU C 1 16  ? -27.241 17.409  42.593  1   97.94  ? 12  GLU C OE2 1 
ATOM   4695 N  N   . GLY C 1 17  ? -31.583 15.598  40.481  1   112.61 ? 13  GLY C N   1 
ATOM   4696 C  CA  . GLY C 1 17  ? -32.678 14.974  41.245  1   125.84 ? 13  GLY C CA  1 
ATOM   4697 C  C   . GLY C 1 17  ? -32.158 13.958  42.239  1   126.47 ? 13  GLY C C   1 
ATOM   4698 O  O   . GLY C 1 17  ? -30.944 13.965  42.515  1   113.58 ? 13  GLY C O   1 
ATOM   4699 N  N   . THR C 1 18  ? -33.022 13.038  42.66   1   137.6  ? 14  THR C N   1 
ATOM   4700 C  CA  . THR C 1 18  ? -32.544 11.897  43.455  1   136.63 ? 14  THR C CA  1 
ATOM   4701 C  C   . THR C 1 18  ? -31.988 10.956  42.422  1   130.89 ? 14  THR C C   1 
ATOM   4702 O  O   . THR C 1 18  ? -31.302 9.991   42.81   1   126.32 ? 14  THR C O   1 
ATOM   4703 C  CB  . THR C 1 18  ? -33.722 11.275  44.195  1   131.37 ? 14  THR C CB  1 
ATOM   4704 O  OG1 . THR C 1 18  ? -34.542 10.763  43.151  1   123.24 ? 14  THR C OG1 1 
ATOM   4705 C  CG2 . THR C 1 18  ? -34.501 12.288  45.012  1   118.9  ? 14  THR C CG2 1 
ATOM   4706 N  N   . TYR C 1 19  ? -32.269 11.237  41.142  1   123.72 ? 15  TYR C N   1 
ATOM   4707 C  CA  . TYR C 1 19  ? -31.772 10.413  40.012  1   115.35 ? 15  TYR C CA  1 
ATOM   4708 C  C   . TYR C 1 19  ? -30.334 10.741  39.716  1   109.97 ? 15  TYR C C   1 
ATOM   4709 O  O   . TYR C 1 19  ? -29.878 10.445  38.595  1   117.57 ? 15  TYR C O   1 
ATOM   4710 C  CB  . TYR C 1 19  ? -32.465 10.879  38.733  1   121.86 ? 15  TYR C CB  1 
ATOM   4711 C  CG  . TYR C 1 19  ? -33.982 11.005  38.751  1   132.65 ? 15  TYR C CG  1 
ATOM   4712 C  CD1 . TYR C 1 19  ? -34.792 9.923   38.429  1   134.07 ? 15  TYR C CD1 1 
ATOM   4713 C  CD2 . TYR C 1 19  ? -34.603 12.213  39.046  1   124.41 ? 15  TYR C CD2 1 
ATOM   4714 C  CE1 . TYR C 1 19  ? -36.172 10.032  38.425  1   134.24 ? 15  TYR C CE1 1 
ATOM   4715 C  CE2 . TYR C 1 19  ? -35.983 12.334  39.046  1   113.71 ? 15  TYR C CE2 1 
ATOM   4716 C  CZ  . TYR C 1 19  ? -36.77  11.24   38.735  1   123.96 ? 15  TYR C CZ  1 
ATOM   4717 O  OH  . TYR C 1 19  ? -38.131 11.34   38.735  1   93.66  ? 15  TYR C OH  1 
ATOM   4718 N  N   . GLY C 1 20  ? -29.627 11.351  40.665  1   99     ? 16  GLY C N   1 
ATOM   4719 C  CA  . GLY C 1 20  ? -28.266 11.819  40.381  1   88.2   ? 16  GLY C CA  1 
ATOM   4720 C  C   . GLY C 1 20  ? -28.343 13.117  39.607  1   85.18  ? 16  GLY C C   1 
ATOM   4721 O  O   . GLY C 1 20  ? -29.367 13.815  39.716  1   78.46  ? 16  GLY C O   1 
ATOM   4722 N  N   . VAL C 1 21  ? -27.303 13.422  38.836  1   76.64  ? 17  VAL C N   1 
ATOM   4723 C  CA  . VAL C 1 21  ? -27.282 14.706  38.088  1   70.25  ? 17  VAL C CA  1 
ATOM   4724 C  C   . VAL C 1 21  ? -27.488 14.449  36.592  1   66.17  ? 17  VAL C C   1 
ATOM   4725 O  O   . VAL C 1 21  ? -27.307 13.298  36.161  1   61.34  ? 17  VAL C O   1 
ATOM   4726 C  CB  . VAL C 1 21  ? -25.974 15.474  38.343  1   79.02  ? 17  VAL C CB  1 
ATOM   4727 C  CG1 . VAL C 1 21  ? -26.151 16.98   38.205  1   81.59  ? 17  VAL C CG1 1 
ATOM   4728 C  CG2 . VAL C 1 21  ? -25.369 15.13   39.696  1   90.23  ? 17  VAL C CG2 1 
ATOM   4729 N  N   . VAL C 1 22  ? -27.884 15.482  35.859  1   56.46  ? 18  VAL C N   1 
ATOM   4730 C  CA  . VAL C 1 22  ? -28.113 15.431  34.421  1   48.94  ? 18  VAL C CA  1 
ATOM   4731 C  C   . VAL C 1 22  ? -27.259 16.53   33.794  1   51.01  ? 18  VAL C C   1 
ATOM   4732 O  O   . VAL C 1 22  ? -27.341 17.676  34.236  1   52.08  ? 18  VAL C O   1 
ATOM   4733 C  CB  . VAL C 1 22  ? -29.583 15.623  34.009  1   44.81  ? 18  VAL C CB  1 
ATOM   4734 C  CG1 . VAL C 1 22  ? -29.753 15.547  32.501  1   40.83  ? 18  VAL C CG1 1 
ATOM   4735 C  CG2 . VAL C 1 22  ? -30.509 14.63   34.698  1   43.87  ? 18  VAL C CG2 1 
ATOM   4736 N  N   . TYR C 1 23  ? -26.423 16.169  32.803  1   49.11  ? 19  TYR C N   1 
ATOM   4737 C  CA  . TYR C 1 23  ? -25.46  17.11   32.261  1   49.07  ? 19  TYR C CA  1 
ATOM   4738 C  C   . TYR C 1 23  ? -25.586 17.167  30.753  1   46.42  ? 19  TYR C C   1 
ATOM   4739 O  O   . TYR C 1 23  ? -25.94  16.187  30.101  1   45.52  ? 19  TYR C O   1 
ATOM   4740 C  CB  . TYR C 1 23  ? -23.981 16.834  32.503  1   55.57  ? 19  TYR C CB  1 
ATOM   4741 C  CG  . TYR C 1 23  ? -23.639 16.234  33.856  1   67.01  ? 19  TYR C CG  1 
ATOM   4742 C  CD1 . TYR C 1 23  ? -23.846 14.87   34.094  1   77.17  ? 19  TYR C CD1 1 
ATOM   4743 C  CD2 . TYR C 1 23  ? -23.061 17.001  34.869  1   73     ? 19  TYR C CD2 1 
ATOM   4744 C  CE1 . TYR C 1 23  ? -23.502 14.278  35.302  1   85.91  ? 19  TYR C CE1 1 
ATOM   4745 C  CE2 . TYR C 1 23  ? -22.722 16.422  36.088  1   87.21  ? 19  TYR C CE2 1 
ATOM   4746 C  CZ  . TYR C 1 23  ? -22.945 15.062  36.305  1   94.03  ? 19  TYR C CZ  1 
ATOM   4747 O  OH  . TYR C 1 23  ? -22.614 14.45   37.485  1   94.02  ? 19  TYR C OH  1 
ATOM   4748 N  N   . LYS C 1 24  ? -25.289 18.351  30.222  1   45.4   ? 20  LYS C N   1 
ATOM   4749 C  CA  . LYS C 1 24  ? -25.205 18.541  28.791  1   41.47  ? 20  LYS C CA  1 
ATOM   4750 C  C   . LYS C 1 24  ? -23.803 18.131  28.407  1   41.57  ? 20  LYS C C   1 
ATOM   4751 O  O   . LYS C 1 24  ? -22.859 18.43   29.125  1   41.46  ? 20  LYS C O   1 
ATOM   4752 C  CB  . LYS C 1 24  ? -25.392 20.023  28.473  1   42.63  ? 20  LYS C CB  1 
ATOM   4753 C  CG  . LYS C 1 24  ? -25.481 20.296  26.988  1   43.89  ? 20  LYS C CG  1 
ATOM   4754 C  CD  . LYS C 1 24  ? -25.761 21.762  26.707  1   45.26  ? 20  LYS C CD  1 
ATOM   4755 C  CE  . LYS C 1 24  ? -25.482 22.066  25.281  1   47.45  ? 20  LYS C CE  1 
ATOM   4756 N  NZ  . LYS C 1 24  ? -26.466 23.039  24.806  1   50.06  ? 20  LYS C NZ  1 
ATOM   4757 N  N   . ALA C 1 25  ? -23.692 17.414  27.293  1   42     ? 21  ALA C N   1 
ATOM   4758 C  CA  . ALA C 1 25  ? -22.402 16.904  26.868  1   44.59  ? 21  ALA C CA  1 
ATOM   4759 C  C   . ALA C 1 25  ? -22.328 16.994  25.351  1   44.56  ? 21  ALA C C   1 
ATOM   4760 O  O   . ALA C 1 25  ? -23.356 17.198  24.689  1   44.58  ? 21  ALA C O   1 
ATOM   4761 C  CB  . ALA C 1 25  ? -22.275 15.468  27.332  1   43.95  ? 21  ALA C CB  1 
ATOM   4762 N  N   A ARG C 1 26  ? -21.102 16.863  24.841  0.7 45.51  ? 22  ARG C N   1 
ATOM   4763 N  N   B ARG C 1 26  ? -21.128 16.795  24.801  0.3 44.86  ? 22  ARG C N   1 
ATOM   4764 C  CA  A ARG C 1 26  ? -20.827 16.827  23.419  0.7 47.99  ? 22  ARG C CA  1 
ATOM   4765 C  CA  B ARG C 1 26  ? -20.94  16.846  23.363  0.3 45.35  ? 22  ARG C CA  1 
ATOM   4766 C  C   A ARG C 1 26  ? -20.109 15.511  23.125  0.7 47.93  ? 22  ARG C C   1 
ATOM   4767 C  C   B ARG C 1 26  ? -20.034 15.688  22.947  0.3 46.61  ? 22  ARG C C   1 
ATOM   4768 O  O   A ARG C 1 26  ? -19.177 15.136  23.835  0.7 49.19  ? 22  ARG C O   1 
ATOM   4769 O  O   B ARG C 1 26  ? -18.9   15.586  23.413  0.3 48.3   ? 22  ARG C O   1 
ATOM   4770 C  CB  A ARG C 1 26  ? -19.979 18.045  23.01   0.7 52.54  ? 22  ARG C CB  1 
ATOM   4771 C  CB  B ARG C 1 26  ? -20.4   18.231  22.981  0.3 46.31  ? 22  ARG C CB  1 
ATOM   4772 C  CG  A ARG C 1 26  ? -19.553 18.071  21.544  0.7 59.73  ? 22  ARG C CG  1 
ATOM   4773 C  CG  B ARG C 1 26  ? -20.274 18.54   21.495  0.3 47.22  ? 22  ARG C CG  1 
ATOM   4774 C  CD  A ARG C 1 26  ? -18.584 19.137  20.971  0.7 63.37  ? 22  ARG C CD  1 
ATOM   4775 C  CD  B ARG C 1 26  ? -19.593 19.889  21.222  0.3 48.49  ? 22  ARG C CD  1 
ATOM   4776 N  NE  A ARG C 1 26  ? -17.313 19.318  21.686  0.7 67.37  ? 22  ARG C NE  1 
ATOM   4777 N  NE  B ARG C 1 26  ? -20.536 21.002  21.076  0.3 47.31  ? 22  ARG C NE  1 
ATOM   4778 C  CZ  A ARG C 1 26  ? -17.15  20.081  22.777  0.7 69.82  ? 22  ARG C CZ  1 
ATOM   4779 C  CZ  B ARG C 1 26  ? -21.323 21.112  20.018  0.3 46.73  ? 22  ARG C CZ  1 
ATOM   4780 N  NH1 A ARG C 1 26  ? -18.157 20.807  23.281  0.7 66.96  ? 22  ARG C NH1 1 
ATOM   4781 N  NH1 B ARG C 1 26  ? -21.208 20.256  19.022  0.3 46.32  ? 22  ARG C NH1 1 
ATOM   4782 N  NH2 A ARG C 1 26  ? -15.956 20.123  23.352  0.7 68.82  ? 22  ARG C NH2 1 
ATOM   4783 N  NH2 B ARG C 1 26  ? -22.212 22.083  19.951  0.3 46.6   ? 22  ARG C NH2 1 
ATOM   4784 N  N   . ASN C 1 27  ? -20.553 14.808  22.08   1   45.74  ? 23  ASN C N   1 
ATOM   4785 C  CA  . ASN C 1 27  ? -19.758 13.735  21.509  1   46.78  ? 23  ASN C CA  1 
ATOM   4786 C  C   . ASN C 1 27  ? -18.562 14.339  20.775  1   49.74  ? 23  ASN C C   1 
ATOM   4787 O  O   . ASN C 1 27  ? -18.726 15.054  19.791  1   49.58  ? 23  ASN C O   1 
ATOM   4788 C  CB  . ASN C 1 27  ? -20.566 12.921  20.509  1   46     ? 23  ASN C CB  1 
ATOM   4789 C  CG  . ASN C 1 27  ? -19.878 11.634  20.106  1   45.92  ? 23  ASN C CG  1 
ATOM   4790 O  OD1 . ASN C 1 27  ? -18.701 11.641  19.724  1   45.19  ? 23  ASN C OD1 1 
ATOM   4791 N  ND2 . ASN C 1 27  ? -20.607 10.528  20.199  1   43.79  ? 23  ASN C ND2 1 
ATOM   4792 N  N   . LYS C 1 28  ? -17.353 14.034  21.242  1   50.91  ? 24  LYS C N   1 
ATOM   4793 C  CA  . LYS C 1 28  ? -16.175 14.679  20.707  1   53.75  ? 24  LYS C CA  1 
ATOM   4794 C  C   . LYS C 1 28  ? -15.989 14.281  19.247  1   55.29  ? 24  LYS C C   1 
ATOM   4795 O  O   . LYS C 1 28  ? -15.389 15.023  18.457  1   57.17  ? 24  LYS C O   1 
ATOM   4796 C  CB  . LYS C 1 28  ? -14.951 14.214  21.5    1   58.93  ? 24  LYS C CB  1 
ATOM   4797 C  CG  . LYS C 1 28  ? -14.953 14.523  22.988  1   62.89  ? 24  LYS C CG  1 
ATOM   4798 C  CD  . LYS C 1 28  ? -13.564 14.36   23.599  1   68.98  ? 24  LYS C CD  1 
ATOM   4799 C  CE  . LYS C 1 28  ? -13.656 14.087  25.079  1   71.9   ? 24  LYS C CE  1 
ATOM   4800 N  NZ  . LYS C 1 28  ? -12.525 14.534  25.9    1   74.84  ? 24  LYS C NZ  1 
ATOM   4801 N  N   . LEU C 1 29  ? -16.461 13.072  18.908  1   53.26  ? 25  LEU C N   1 
ATOM   4802 C  CA  . LEU C 1 29  ? -16.147 12.459  17.622  1   52.59  ? 25  LEU C CA  1 
ATOM   4803 C  C   . LEU C 1 29  ? -17.206 12.815  16.571  1   52.01  ? 25  LEU C C   1 
ATOM   4804 O  O   . LEU C 1 29  ? -16.854 13.114  15.423  1   53.83  ? 25  LEU C O   1 
ATOM   4805 C  CB  . LEU C 1 29  ? -15.972 10.947  17.766  1   51     ? 25  LEU C CB  1 
ATOM   4806 C  CG  . LEU C 1 29  ? -14.647 10.446  18.346  1   51.58  ? 25  LEU C CG  1 
ATOM   4807 C  CD1 . LEU C 1 29  ? -14.761 8.947   18.556  1   50.66  ? 25  LEU C CD1 1 
ATOM   4808 C  CD2 . LEU C 1 29  ? -13.493 10.751  17.419  1   53.18  ? 25  LEU C CD2 1 
ATOM   4809 N  N   . THR C 1 30  ? -18.489 12.786  16.977  1   47.61  ? 26  THR C N   1 
ATOM   4810 C  CA  . THR C 1 30  ? -19.596 13.018  16.069  1   46.29  ? 26  THR C CA  1 
ATOM   4811 C  C   . THR C 1 30  ? -20.077 14.469  16.127  1   46.44  ? 26  THR C C   1 
ATOM   4812 O  O   . THR C 1 30  ? -20.713 14.941  15.187  1   47.12  ? 26  THR C O   1 
ATOM   4813 C  CB  . THR C 1 30  ? -20.742 12.049  16.338  1   44.43  ? 26  THR C CB  1 
ATOM   4814 O  OG1 . THR C 1 30  ? -21.323 12.386  17.591  1   42.76  ? 26  THR C OG1 1 
ATOM   4815 C  CG2 . THR C 1 30  ? -20.321 10.592  16.318  1   45.44  ? 26  THR C CG2 1 
ATOM   4816 N  N   . GLY C 1 31  ? -19.806 15.172  17.23   1   46.1   ? 27  GLY C N   1 
ATOM   4817 C  CA  . GLY C 1 31  ? -20.272 16.541  17.384  1   46.59  ? 27  GLY C CA  1 
ATOM   4818 C  C   . GLY C 1 31  ? -21.666 16.617  18.012  1   45.42  ? 27  GLY C C   1 
ATOM   4819 O  O   . GLY C 1 31  ? -22.146 17.706  18.332  1   46.3   ? 27  GLY C O   1 
ATOM   4820 N  N   . GLU C 1 32  ? -22.308 15.457  18.188  1   43.95  ? 28  GLU C N   1 
ATOM   4821 C  CA  . GLU C 1 32  ? -23.674 15.383  18.668  1   42.75  ? 28  GLU C CA  1 
ATOM   4822 C  C   . GLU C 1 32  ? -23.707 15.85   20.115  1   43.32  ? 28  GLU C C   1 
ATOM   4823 O  O   . GLU C 1 32  ? -22.872 15.432  20.924  1   44.17  ? 28  GLU C O   1 
ATOM   4824 C  CB  . GLU C 1 32  ? -24.205 13.956  18.51   1   43.21  ? 28  GLU C CB  1 
ATOM   4825 C  CG  . GLU C 1 32  ? -25.516 13.726  19.262  1   43.61  ? 28  GLU C CG  1 
ATOM   4826 C  CD  . GLU C 1 32  ? -26.145 12.349  19.108  1   44.2   ? 28  GLU C CD  1 
ATOM   4827 O  OE1 . GLU C 1 32  ? -25.416 11.335  19.212  1   43.44  ? 28  GLU C OE1 1 
ATOM   4828 O  OE2 . GLU C 1 32  ? -27.389 12.295  18.916  1   44.64  ? 28  GLU C OE2 1 
ATOM   4829 N  N   . VAL C 1 33  ? -24.687 16.71   20.416  1   42.75  ? 29  VAL C N   1 
ATOM   4830 C  CA  . VAL C 1 33  ? -24.918 17.24   21.751  1   41.32  ? 29  VAL C CA  1 
ATOM   4831 C  C   . VAL C 1 33  ? -25.964 16.365  22.427  1   40.39  ? 29  VAL C C   1 
ATOM   4832 O  O   . VAL C 1 33  ? -26.985 16.064  21.826  1   41.17  ? 29  VAL C O   1 
ATOM   4833 C  CB  . VAL C 1 33  ? -25.38  18.707  21.681  1   40.07  ? 29  VAL C CB  1 
ATOM   4834 C  CG1 . VAL C 1 33  ? -25.763 19.228  23.056  1   38.41  ? 29  VAL C CG1 1 
ATOM   4835 C  CG2 . VAL C 1 33  ? -24.302 19.588  21.055  1   41.85  ? 29  VAL C CG2 1 
ATOM   4836 N  N   . VAL C 1 34  ? -25.704 15.955  23.674  1   40.26  ? 30  VAL C N   1 
ATOM   4837 C  CA  . VAL C 1 34  ? -26.57  15.001  24.356  1   39.05  ? 30  VAL C CA  1 
ATOM   4838 C  C   . VAL C 1 34  ? -26.825 15.463  25.787  1   39.14  ? 30  VAL C C   1 
ATOM   4839 O  O   . VAL C 1 34  ? -26.212 16.412  26.271  1   42.65  ? 30  VAL C O   1 
ATOM   4840 C  CB  . VAL C 1 34  ? -25.951 13.588  24.33   1   38.86  ? 30  VAL C CB  1 
ATOM   4841 C  CG1 . VAL C 1 34  ? -25.736 13.09   22.896  1   40.49  ? 30  VAL C CG1 1 
ATOM   4842 C  CG2 . VAL C 1 34  ? -24.641 13.531  25.094  1   37.43  ? 30  VAL C CG2 1 
ATOM   4843 N  N   . ALA C 1 35  ? -27.747 14.778  26.454  1   37.58  ? 31  ALA C N   1 
ATOM   4844 C  CA  . ALA C 1 35  ? -27.929 14.928  27.882  1   37.57  ? 31  ALA C CA  1 
ATOM   4845 C  C   . ALA C 1 35  ? -27.558 13.595  28.532  1   38.75  ? 31  ALA C C   1 
ATOM   4846 O  O   . ALA C 1 35  ? -28.056 12.553  28.112  1   39.46  ? 31  ALA C O   1 
ATOM   4847 C  CB  . ALA C 1 35  ? -29.374 15.29   28.145  1   36.82  ? 31  ALA C CB  1 
ATOM   4848 N  N   . LEU C 1 36  ? -26.653 13.633  29.51   1   38.21  ? 32  LEU C N   1 
ATOM   4849 C  CA  . LEU C 1 36  ? -26.208 12.454  30.228  1   39.97  ? 32  LEU C CA  1 
ATOM   4850 C  C   . LEU C 1 36  ? -26.877 12.433  31.598  1   44.83  ? 32  LEU C C   1 
ATOM   4851 O  O   . LEU C 1 36  ? -26.677 13.348  32.397  1   52.44  ? 32  LEU C O   1 
ATOM   4852 C  CB  . LEU C 1 36  ? -24.693 12.577  30.359  1   38.35  ? 32  LEU C CB  1 
ATOM   4853 C  CG  . LEU C 1 36  ? -23.921 12.432  29.049  1   39.11  ? 32  LEU C CG  1 
ATOM   4854 C  CD1 . LEU C 1 36  ? -22.427 12.594  29.288  1   40.38  ? 32  LEU C CD1 1 
ATOM   4855 C  CD2 . LEU C 1 36  ? -24.241 11.108  28.36   1   36.25  ? 32  LEU C CD2 1 
ATOM   4856 N  N   . LYS C 1 37  ? -27.717 11.429  31.858  1   43.67  ? 33  LYS C N   1 
ATOM   4857 C  CA  . LYS C 1 37  ? -28.261 11.244  33.195  1   42.68  ? 33  LYS C CA  1 
ATOM   4858 C  C   . LYS C 1 37  ? -27.415 10.172  33.881  1   44.76  ? 33  LYS C C   1 
ATOM   4859 O  O   . LYS C 1 37  ? -27.42  9.037   33.445  1   50.98  ? 33  LYS C O   1 
ATOM   4860 C  CB  . LYS C 1 37  ? -29.757 10.947  33.041  1   38.79  ? 33  LYS C CB  1 
ATOM   4861 C  CG  . LYS C 1 37  ? -30.567 10.686  34.308  1   41.29  ? 33  LYS C CG  1 
ATOM   4862 C  CD  . LYS C 1 37  ? -32.03  10.248  34.19   1   41.73  ? 33  LYS C CD  1 
ATOM   4863 C  CE  . LYS C 1 37  ? -33.013 11.268  33.684  1   47.23  ? 33  LYS C CE  1 
ATOM   4864 N  NZ  . LYS C 1 37  ? -34.425 10.91   33.893  1   50.6   ? 33  LYS C NZ  1 
ATOM   4865 N  N   . LYS C 1 38  ? -26.622 10.544  34.886  1   46.62  ? 34  LYS C N   1 
ATOM   4866 C  CA  . LYS C 1 38  ? -25.77  9.617   35.62   1   50.78  ? 34  LYS C CA  1 
ATOM   4867 C  C   . LYS C 1 38  ? -26.54  9.065   36.817  1   55.06  ? 34  LYS C C   1 
ATOM   4868 O  O   . LYS C 1 38  ? -26.958 9.844   37.664  1   60.74  ? 34  LYS C O   1 
ATOM   4869 C  CB  . LYS C 1 38  ? -24.534 10.341  36.165  1   51.9   ? 34  LYS C CB  1 
ATOM   4870 C  CG  . LYS C 1 38  ? -23.846 9.644   37.314  1   58.3   ? 34  LYS C CG  1 
ATOM   4871 C  CD  . LYS C 1 38  ? -23.008 10.572  38.189  1   71.35  ? 34  LYS C CD  1 
ATOM   4872 C  CE  . LYS C 1 38  ? -21.546 10.723  37.829  1   84.71  ? 34  LYS C CE  1 
ATOM   4873 N  NZ  . LYS C 1 38  ? -20.675 9.691   38.407  1   88.79  ? 34  LYS C NZ  1 
ATOM   4874 N  N   . ILE C 1 39  ? -26.745 7.737   36.862  1   54.96  ? 35  ILE C N   1 
ATOM   4875 C  CA  . ILE C 1 39  ? -27.492 7.059   37.914  1   55.43  ? 35  ILE C CA  1 
ATOM   4876 C  C   . ILE C 1 39  ? -26.487 6.408   38.855  1   65.23  ? 35  ILE C C   1 
ATOM   4877 O  O   . ILE C 1 39  ? -25.69  5.554   38.442  1   65.22  ? 35  ILE C O   1 
ATOM   4878 C  CB  . ILE C 1 39  ? -28.437 5.972   37.368  1   54.39  ? 35  ILE C CB  1 
ATOM   4879 C  CG1 . ILE C 1 39  ? -29.536 6.489   36.406  1   56.14  ? 35  ILE C CG1 1 
ATOM   4880 C  CG2 . ILE C 1 39  ? -29.002 5.159   38.531  1   53.25  ? 35  ILE C CG2 1 
ATOM   4881 C  CD1 . ILE C 1 39  ? -30.801 7.052   37.053  1   63.86  ? 35  ILE C CD1 1 
ATOM   4882 N  N   . ARG C 1 40  ? -26.558 6.802   40.132  1   74.76  ? 36  ARG C N   1 
ATOM   4883 C  CA  . ARG C 1 40  ? -25.552 6.391   41.103  1   80.73  ? 36  ARG C CA  1 
ATOM   4884 C  C   . ARG C 1 40  ? -25.896 4.996   41.623  1   69.13  ? 36  ARG C C   1 
ATOM   4885 O  O   . ARG C 1 40  ? -26.999 4.768   42.11   1   68.89  ? 36  ARG C O   1 
ATOM   4886 C  CB  . ARG C 1 40  ? -25.349 7.483   42.168  1   94.93  ? 36  ARG C CB  1 
ATOM   4887 C  CG  . ARG C 1 40  ? -24.108 7.304   43.035  1   106.65 ? 36  ARG C CG  1 
ATOM   4888 C  CD  . ARG C 1 40  ? -22.916 6.803   42.214  1   107.99 ? 36  ARG C CD  1 
ATOM   4889 N  NE  . ARG C 1 40  ? -21.614 6.751   42.895  1   110.29 ? 36  ARG C NE  1 
ATOM   4890 C  CZ  . ARG C 1 40  ? -20.433 6.992   42.319  1   107.37 ? 36  ARG C CZ  1 
ATOM   4891 N  NH1 . ARG C 1 40  ? -20.377 7.376   41.052  1   100.23 ? 36  ARG C NH1 1 
ATOM   4892 N  NH2 . ARG C 1 40  ? -19.316 6.838   43.013  1   107.02 ? 36  ARG C NH2 1 
ATOM   4893 N  N   . LEU C 1 41  ? -24.948 4.068   41.489  1   63.9   ? 37  LEU C N   1 
ATOM   4894 C  CA  . LEU C 1 41  ? -25.204 2.671   41.806  1   62.51  ? 37  LEU C CA  1 
ATOM   4895 C  C   . LEU C 1 41  ? -24.781 2.35    43.239  1   66.59  ? 37  LEU C C   1 
ATOM   4896 O  O   . LEU C 1 41  ? -23.672 2.661   43.656  1   67.14  ? 37  LEU C O   1 
ATOM   4897 C  CB  . LEU C 1 41  ? -24.482 1.771   40.81   1   55.17  ? 37  LEU C CB  1 
ATOM   4898 C  CG  . LEU C 1 41  ? -25.112 1.705   39.419  1   53.15  ? 37  LEU C CG  1 
ATOM   4899 C  CD1 . LEU C 1 41  ? -24.34  0.794   38.459  1   50.87  ? 37  LEU C CD1 1 
ATOM   4900 C  CD2 . LEU C 1 41  ? -26.53  1.227   39.616  1   52.64  ? 37  LEU C CD2 1 
ATOM   4901 N  N   . ASP C 1 42  ? -25.819 1.554   43.886  1   65.61  ? 38  ASP C N   1 
ATOM   4902 C  CA  . ASP C 1 42  ? -25.56  1.038   45.257  1   65.65  ? 38  ASP C CA  1 
ATOM   4903 C  C   . ASP C 1 42  ? -24.949 -0.351  45.087  1   59.46  ? 38  ASP C C   1 
ATOM   4904 O  O   . ASP C 1 42  ? -25.704 -1.323  45.171  1   59.78  ? 38  ASP C O   1 
ATOM   4905 C  CB  . ASP C 1 42  ? -26.836 1.136   46.074  1   71.17  ? 38  ASP C CB  1 
ATOM   4906 C  CG  . ASP C 1 42  ? -27.258 2.546   46.458  1   79.45  ? 38  ASP C CG  1 
ATOM   4907 O  OD1 . ASP C 1 42  ? -26.42  3.459   46.34   1   80.15  ? 38  ASP C OD1 1 
ATOM   4908 O  OD2 . ASP C 1 42  ? -28.422 2.718   46.872  1   85.22  ? 38  ASP C OD2 1 
ATOM   4909 N  N   . THR C 1 43  ? -23.505 -0.406  44.998  1   52.3   ? 39  THR C N   1 
ATOM   4910 C  CA  . THR C 1 43  ? -22.996 -1.702  44.583  1   49.67  ? 39  THR C CA  1 
ATOM   4911 C  C   . THR C 1 43  ? -22.743 -2.631  45.768  1   52.48  ? 39  THR C C   1 
ATOM   4912 O  O   . THR C 1 43  ? -22.229 -3.732  45.568  1   55.2   ? 39  THR C O   1 
ATOM   4913 C  CB  . THR C 1 43  ? -21.728 -1.554  43.743  1   49.35  ? 39  THR C CB  1 
ATOM   4914 O  OG1 . THR C 1 43  ? -20.739 -0.915  44.536  1   52.8   ? 39  THR C OG1 1 
ATOM   4915 C  CG2 . THR C 1 43  ? -21.907 -0.727  42.487  1   46.93  ? 39  THR C CG2 1 
ATOM   4916 N  N   . GLU C 1 44  ? -23.04  -2.189  46.998  1   52.55  ? 40  GLU C N   1 
ATOM   4917 C  CA  . GLU C 1 44  ? -22.863 -3.061  48.152  1   54.25  ? 40  GLU C CA  1 
ATOM   4918 C  C   . GLU C 1 44  ? -24.175 -3.064  48.924  1   55.02  ? 40  GLU C C   1 
ATOM   4919 O  O   . GLU C 1 44  ? -24.221 -3.594  50.027  1   60.89  ? 40  GLU C O   1 
ATOM   4920 C  CB  . GLU C 1 44  ? -21.752 -2.701  49.153  1   54.75  ? 40  GLU C CB  1 
ATOM   4921 C  CG  . GLU C 1 44  ? -20.337 -2.559  48.586  1   55.64  ? 40  GLU C CG  1 
ATOM   4922 C  CD  . GLU C 1 44  ? -20.063 -1.506  47.508  1   54.14  ? 40  GLU C CD  1 
ATOM   4923 O  OE1 . GLU C 1 44  ? -19.358 -1.81   46.519  1   53.36  ? 40  GLU C OE1 1 
ATOM   4924 O  OE2 . GLU C 1 44  ? -20.575 -0.362  47.627  1   53.41  ? 40  GLU C OE2 1 
ATOM   4925 N  N   . THR C 1 45  ? -25.216 -2.422  48.379  1   50.82  ? 41  THR C N   1 
ATOM   4926 C  CA  . THR C 1 45  ? -26.451 -2.285  49.133  1   50.33  ? 41  THR C CA  1 
ATOM   4927 C  C   . THR C 1 45  ? -27.703 -2.6    48.313  1   48.35  ? 41  THR C C   1 
ATOM   4928 O  O   . THR C 1 45  ? -28.239 -3.688  48.469  1   51.26  ? 41  THR C O   1 
ATOM   4929 C  CB  . THR C 1 45  ? -26.53  -1.005  49.965  1   50.16  ? 41  THR C CB  1 
ATOM   4930 O  OG1 . THR C 1 45  ? -26.147 0.068   49.114  1   48.64  ? 41  THR C OG1 1 
ATOM   4931 C  CG2 . THR C 1 45  ? -25.633 -1.069  51.186  1   51.94  ? 41  THR C CG2 1 
ATOM   4932 N  N   A GLU C 1 46  ? -28.147 -1.657  47.471  0.5 45.95  ? 42  GLU C N   1 
ATOM   4933 N  N   B GLU C 1 46  ? -28.148 -1.705  47.432  0.5 45.65  ? 42  GLU C N   1 
ATOM   4934 C  CA  A GLU C 1 46  ? -29.445 -1.736  46.817  0.5 44.7   ? 42  GLU C CA  1 
ATOM   4935 C  CA  B GLU C 1 46  ? -29.452 -1.951  46.843  0.5 44.35  ? 42  GLU C CA  1 
ATOM   4936 C  C   A GLU C 1 46  ? -29.321 -2.283  45.389  0.5 43.13  ? 42  GLU C C   1 
ATOM   4937 C  C   B GLU C 1 46  ? -29.369 -2.202  45.33   0.5 42.65  ? 42  GLU C C   1 
ATOM   4938 O  O   A GLU C 1 46  ? -30.259 -2.909  44.898  0.5 42.05  ? 42  GLU C O   1 
ATOM   4939 O  O   B GLU C 1 46  ? -30.375 -2.569  44.724  0.5 41.09  ? 42  GLU C O   1 
ATOM   4940 C  CB  A GLU C 1 46  ? -30.281 -0.447  46.901  0.5 44.95  ? 42  GLU C CB  1 
ATOM   4941 C  CB  B GLU C 1 46  ? -30.519 -0.973  47.357  0.5 44.69  ? 42  GLU C CB  1 
ATOM   4942 C  CG  A GLU C 1 46  ? -31.022 -0.216  48.226  0.5 46.83  ? 42  GLU C CG  1 
ATOM   4943 C  CG  B GLU C 1 46  ? -30.74  -0.973  48.876  0.5 46.11  ? 42  GLU C CG  1 
ATOM   4944 C  CD  A GLU C 1 46  ? -32.289 0.657   48.236  0.5 46.06  ? 42  GLU C CD  1 
ATOM   4945 C  CD  B GLU C 1 46  ? -31.082 -2.272  49.602  0.5 48.64  ? 42  GLU C CD  1 
ATOM   4946 O  OE1 A GLU C 1 46  ? -32.835 0.875   49.325  0.5 46     ? 42  GLU C OE1 1 
ATOM   4947 O  OE1 B GLU C 1 46  ? -32.103 -2.929  49.268  0.5 46.95  ? 42  GLU C OE1 1 
ATOM   4948 O  OE2 A GLU C 1 46  ? -32.774 1.12    47.18   0.5 46.1   ? 42  GLU C OE2 1 
ATOM   4949 O  OE2 B GLU C 1 46  ? -30.3   -2.636  50.529  0.5 52.41  ? 42  GLU C OE2 1 
ATOM   4950 N  N   . GLY C 1 47  ? -28.187 -2.033  44.719  1   42.04  ? 43  GLY C N   1 
ATOM   4951 C  CA  . GLY C 1 47  ? -28.01  -2.359  43.308  1   39.99  ? 43  GLY C CA  1 
ATOM   4952 C  C   . GLY C 1 47  ? -28.61  -1.285  42.4    1   41.15  ? 43  GLY C C   1 
ATOM   4953 O  O   . GLY C 1 47  ? -28.695 -0.123  42.781  1   45.64  ? 43  GLY C O   1 
ATOM   4954 N  N   . VAL C 1 48  ? -29.041 -1.656  41.188  1   38.43  ? 44  VAL C N   1 
ATOM   4955 C  CA  . VAL C 1 48  ? -29.622 -0.704  40.263  1   35.67  ? 44  VAL C CA  1 
ATOM   4956 C  C   . VAL C 1 48  ? -31.009 -0.325  40.754  1   37.69  ? 44  VAL C C   1 
ATOM   4957 O  O   . VAL C 1 48  ? -31.832 -1.219  40.941  1   40.6   ? 44  VAL C O   1 
ATOM   4958 C  CB  . VAL C 1 48  ? -29.757 -1.345  38.877  1   33.11  ? 44  VAL C CB  1 
ATOM   4959 C  CG1 . VAL C 1 48  ? -30.308 -0.345  37.876  1   30.17  ? 44  VAL C CG1 1 
ATOM   4960 C  CG2 . VAL C 1 48  ? -28.436 -1.926  38.396  1   33.49  ? 44  VAL C CG2 1 
ATOM   4961 N  N   . PRO C 1 49  ? -31.332 0.982   40.959  1   37.46  ? 45  PRO C N   1 
ATOM   4962 C  CA  . PRO C 1 49  ? -32.666 1.365   41.441  1   36.16  ? 45  PRO C CA  1 
ATOM   4963 C  C   . PRO C 1 49  ? -33.792 1.012   40.476  1   37.32  ? 45  PRO C C   1 
ATOM   4964 O  O   . PRO C 1 49  ? -33.642 1.048   39.236  1   40.59  ? 45  PRO C O   1 
ATOM   4965 C  CB  . PRO C 1 49  ? -32.571 2.872   41.724  1   35.58  ? 45  PRO C CB  1 
ATOM   4966 C  CG  . PRO C 1 49  ? -31.421 3.31    40.848  1   35.43  ? 45  PRO C CG  1 
ATOM   4967 C  CD  . PRO C 1 49  ? -30.44  2.141   40.78   1   35.99  ? 45  PRO C CD  1 
ATOM   4968 N  N   . SER C 1 50  ? -34.894 0.59    41.044  1   37     ? 46  SER C N   1 
ATOM   4969 C  CA  . SER C 1 50  ? -36.095 0.215   40.28   1   38.58  ? 46  SER C CA  1 
ATOM   4970 C  C   . SER C 1 50  ? -36.475 1.321   39.271  1   38.23  ? 46  SER C C   1 
ATOM   4971 O  O   . SER C 1 50  ? -36.964 0.966   38.212  1   38.53  ? 46  SER C O   1 
ATOM   4972 C  CB  . SER C 1 50  ? -37.177 -0.075  41.294  1   40.61  ? 46  SER C CB  1 
ATOM   4973 O  OG  . SER C 1 50  ? -37.757 1.09    41.848  1   40.91  ? 46  SER C OG  1 
ATOM   4974 N  N   . THR C 1 51  ? -36.267 2.588   39.629  1   35.73  ? 47  THR C N   1 
ATOM   4975 C  CA  . THR C 1 51  ? -36.574 3.746   38.753  1   36.52  ? 47  THR C CA  1 
ATOM   4976 C  C   . THR C 1 51  ? -35.779 3.662   37.468  1   34.52  ? 47  THR C C   1 
ATOM   4977 O  O   . THR C 1 51  ? -36.353 3.901   36.415  1   37.04  ? 47  THR C O   1 
ATOM   4978 C  CB  . THR C 1 51  ? -36.398 5.102   39.461  1   35.03  ? 47  THR C CB  1 
ATOM   4979 O  OG1 . THR C 1 51  ? -35.098 5.136   40.033  1   38.65  ? 47  THR C OG1 1 
ATOM   4980 C  CG2 . THR C 1 51  ? -37.453 5.304   40.518  1   36.17  ? 47  THR C CG2 1 
ATOM   4981 N  N   . ALA C 1 52  ? -34.504 3.371   37.591  1   32.29  ? 48  ALA C N   1 
ATOM   4982 C  CA  . ALA C 1 52  ? -33.625 3.252   36.422  1   31.58  ? 48  ALA C CA  1 
ATOM   4983 C  C   . ALA C 1 52  ? -34.044 2.048   35.587  1   32.88  ? 48  ALA C C   1 
ATOM   4984 O  O   . ALA C 1 52  ? -34.02  2.136   34.393  1   31.13  ? 48  ALA C O   1 
ATOM   4985 C  CB  . ALA C 1 52  ? -32.2   3.168   36.913  1   31.54  ? 48  ALA C CB  1 
ATOM   4986 N  N   . ILE C 1 53  ? -34.483 0.995   36.253  1   33.74  ? 49  ILE C N   1 
ATOM   4987 C  CA  . ILE C 1 53  ? -34.802 -0.232  35.547  1   34.85  ? 49  ILE C CA  1 
ATOM   4988 C  C   . ILE C 1 53  ? -36.022 0.018   34.68   1   34.7   ? 49  ILE C C   1 
ATOM   4989 O  O   . ILE C 1 53  ? -36.036 -0.306  33.502  1   38.41  ? 49  ILE C O   1 
ATOM   4990 C  CB  . ILE C 1 53  ? -35.019 -1.371  36.562  1   35.75  ? 49  ILE C CB  1 
ATOM   4991 C  CG1 . ILE C 1 53  ? -33.706 -1.844  37.106  1   33.9   ? 49  ILE C CG1 1 
ATOM   4992 C  CG2 . ILE C 1 53  ? -35.846 -2.53   35.991  1   36.39  ? 49  ILE C CG2 1 
ATOM   4993 C  CD1 . ILE C 1 53  ? -33.866 -2.594  38.408  1   35.16  ? 49  ILE C CD1 1 
ATOM   4994 N  N   . ARG C 1 54  ? -37.024 0.641   35.279  1   34.82  ? 50  ARG C N   1 
ATOM   4995 C  CA  . ARG C 1 54  ? -38.252 0.947   34.582  1   35.18  ? 50  ARG C CA  1 
ATOM   4996 C  C   . ARG C 1 54  ? -37.987 1.981   33.495  1   37.76  ? 50  ARG C C   1 
ATOM   4997 O  O   . ARG C 1 54  ? -38.469 1.825   32.369  1   38.82  ? 50  ARG C O   1 
ATOM   4998 C  CB  . ARG C 1 54  ? -39.285 1.415   35.602  1   33.55  ? 50  ARG C CB  1 
ATOM   4999 C  CG  . ARG C 1 54  ? -39.936 0.278   36.383  1   32.36  ? 50  ARG C CG  1 
ATOM   5000 C  CD  . ARG C 1 54  ? -40.875 0.948   37.365  1   31.79  ? 50  ARG C CD  1 
ATOM   5001 N  NE  . ARG C 1 54  ? -41.544 0.001   38.247  1   33.16  ? 50  ARG C NE  1 
ATOM   5002 C  CZ  . ARG C 1 54  ? -42.348 0.364   39.225  1   35.02  ? 50  ARG C CZ  1 
ATOM   5003 N  NH1 . ARG C 1 54  ? -42.625 1.646   39.4    1   32.96  ? 50  ARG C NH1 1 
ATOM   5004 N  NH2 . ARG C 1 54  ? -42.89  -0.562  40.009  1   35.89  ? 50  ARG C NH2 1 
ATOM   5005 N  N   . GLU C 1 55  ? -37.214 3.023   33.839  1   37.72  ? 51  GLU C N   1 
ATOM   5006 C  CA  . GLU C 1 55  ? -36.966 4.089   32.883  1   36.6   ? 51  GLU C CA  1 
ATOM   5007 C  C   . GLU C 1 55  ? -36.291 3.514   31.639  1   34.62  ? 51  GLU C C   1 
ATOM   5008 O  O   . GLU C 1 55  ? -36.734 3.774   30.539  1   31.1   ? 51  GLU C O   1 
ATOM   5009 C  CB  . GLU C 1 55  ? -36.21  5.283   33.469  1   35.69  ? 51  GLU C CB  1 
ATOM   5010 C  CG  . GLU C 1 55  ? -35.939 6.375   32.436  1   35.23  ? 51  GLU C CG  1 
ATOM   5011 C  CD  . GLU C 1 55  ? -35.392 7.694   32.965  1   38.13  ? 51  GLU C CD  1 
ATOM   5012 O  OE1 . GLU C 1 55  ? -34.973 7.728   34.134  1   33.97  ? 51  GLU C OE1 1 
ATOM   5013 O  OE2 . GLU C 1 55  ? -35.466 8.71    32.216  1   44.27  ? 51  GLU C OE2 1 
ATOM   5014 N  N   . ILE C 1 56  ? -35.203 2.767   31.836  1   36.14  ? 52  ILE C N   1 
ATOM   5015 C  CA  . ILE C 1 56  ? -34.418 2.235   30.73   1   37.84  ? 52  ILE C CA  1 
ATOM   5016 C  C   . ILE C 1 56  ? -35.26  1.273   29.888  1   40.13  ? 52  ILE C C   1 
ATOM   5017 O  O   . ILE C 1 56  ? -35.321 1.419   28.663  1   40.24  ? 52  ILE C O   1 
ATOM   5018 C  CB  . ILE C 1 56  ? -33.096 1.607   31.217  1   34.74  ? 52  ILE C CB  1 
ATOM   5019 C  CG1 . ILE C 1 56  ? -32.266 2.659   31.953  1   34.32  ? 52  ILE C CG1 1 
ATOM   5020 C  CG2 . ILE C 1 56  ? -32.336 1.03    30.023  1   34.05  ? 52  ILE C CG2 1 
ATOM   5021 C  CD1 . ILE C 1 56  ? -31.132 2.126   32.806  1   37.31  ? 52  ILE C CD1 1 
ATOM   5022 N  N   . SER C 1 57  ? -35.941 0.331   30.56   1   39.93  ? 53  SER C N   1 
ATOM   5023 C  CA  . SER C 1 57  ? -36.671 -0.729  29.882  1   40.77  ? 53  SER C CA  1 
ATOM   5024 C  C   . SER C 1 57  ? -37.835 -0.136  29.099  1   40.31  ? 53  SER C C   1 
ATOM   5025 O  O   . SER C 1 57  ? -38.098 -0.543  27.974  1   42.01  ? 53  SER C O   1 
ATOM   5026 C  CB  . SER C 1 57  ? -37.155 -1.786  30.843  1   41.88  ? 53  SER C CB  1 
ATOM   5027 O  OG  . SER C 1 57  ? -37.793 -1.163  31.953  1   47.01  ? 53  SER C OG  1 
ATOM   5028 N  N   . LEU C 1 58  ? -38.53  0.824   29.713  1   38.51  ? 54  LEU C N   1 
ATOM   5029 C  CA  . LEU C 1 58  ? -39.699 1.416   29.086  1   37.24  ? 54  LEU C CA  1 
ATOM   5030 C  C   . LEU C 1 58  ? -39.288 2.27    27.892  1   38.44  ? 54  LEU C C   1 
ATOM   5031 O  O   . LEU C 1 58  ? -39.836 2.075   26.806  1   40.29  ? 54  LEU C O   1 
ATOM   5032 C  CB  . LEU C 1 58  ? -40.616 2.125   30.077  1   34.88  ? 54  LEU C CB  1 
ATOM   5033 C  CG  . LEU C 1 58  ? -41.203 1.165   31.124  1   38.2   ? 54  LEU C CG  1 
ATOM   5034 C  CD1 . LEU C 1 58  ? -42.034 1.758   32.264  1   37.22  ? 54  LEU C CD1 1 
ATOM   5035 C  CD2 . LEU C 1 58  ? -41.975 0.075   30.403  1   40.62  ? 54  LEU C CD2 1 
ATOM   5036 N  N   . LEU C 1 59  ? -38.261 3.123   28.066  1   37.33  ? 55  LEU C N   1 
ATOM   5037 C  CA  . LEU C 1 59  ? -37.772 3.996   27.006  1   38     ? 55  LEU C CA  1 
ATOM   5038 C  C   . LEU C 1 59  ? -37.161 3.228   25.827  1   42.55  ? 55  LEU C C   1 
ATOM   5039 O  O   . LEU C 1 59  ? -37.224 3.711   24.695  1   48.67  ? 55  LEU C O   1 
ATOM   5040 C  CB  . LEU C 1 59  ? -36.779 4.997   27.569  1   35.23  ? 55  LEU C CB  1 
ATOM   5041 C  CG  . LEU C 1 59  ? -37.356 6.212   28.288  1   35.25  ? 55  LEU C CG  1 
ATOM   5042 C  CD1 . LEU C 1 59  ? -36.176 7.052   28.593  1   35.66  ? 55  LEU C CD1 1 
ATOM   5043 C  CD2 . LEU C 1 59  ? -38.315 7.012   27.457  1   34.97  ? 55  LEU C CD2 1 
ATOM   5044 N  N   . LYS C 1 60  ? -36.517 2.078   26.085  1   41.44  ? 56  LYS C N   1 
ATOM   5045 C  CA  . LYS C 1 60  ? -36.016 1.236   25.01   1   45.35  ? 56  LYS C CA  1 
ATOM   5046 C  C   . LYS C 1 60  ? -37.162 0.859   24.075  1   47.58  ? 56  LYS C C   1 
ATOM   5047 O  O   . LYS C 1 60  ? -36.979 0.767   22.87   1   50.28  ? 56  LYS C O   1 
ATOM   5048 C  CB  . LYS C 1 60  ? -35.212 0.015   25.484  1   47.54  ? 56  LYS C CB  1 
ATOM   5049 C  CG  . LYS C 1 60  ? -33.812 0.403   25.939  1   48.81  ? 56  LYS C CG  1 
ATOM   5050 C  CD  . LYS C 1 60  ? -32.801 -0.664  26.345  1   53.09  ? 56  LYS C CD  1 
ATOM   5051 C  CE  . LYS C 1 60  ? -32.039 -1.346  25.24   1   58.27  ? 56  LYS C CE  1 
ATOM   5052 N  NZ  . LYS C 1 60  ? -32.791 -2.473  24.676  1   56.32  ? 56  LYS C NZ  1 
ATOM   5053 N  N   . GLU C 1 61  ? -38.36  0.697   24.64   1   49.49  ? 57  GLU C N   1 
ATOM   5054 C  CA  . GLU C 1 61  ? -39.515 0.261   23.879  1   49.76  ? 57  GLU C CA  1 
ATOM   5055 C  C   . GLU C 1 61  ? -40.122 1.437   23.127  1   49.44  ? 57  GLU C C   1 
ATOM   5056 O  O   . GLU C 1 61  ? -40.379 1.333   21.94   1   61.47  ? 57  GLU C O   1 
ATOM   5057 C  CB  . GLU C 1 61  ? -40.562 -0.42   24.762  1   54.86  ? 57  GLU C CB  1 
ATOM   5058 C  CG  . GLU C 1 61  ? -40.341 -1.924  24.88   1   61.73  ? 57  GLU C CG  1 
ATOM   5059 C  CD  . GLU C 1 61  ? -41.329 -2.7    25.74   1   75.08  ? 57  GLU C CD  1 
ATOM   5060 O  OE1 . GLU C 1 61  ? -40.866 -3.478  26.607  1   83.22  ? 57  GLU C OE1 1 
ATOM   5061 O  OE2 . GLU C 1 61  ? -42.564 -2.545  25.563  1   83.54  ? 57  GLU C OE2 1 
ATOM   5062 N  N   . LEU C 1 62  ? -40.388 2.538   23.824  1   47.5   ? 58  LEU C N   1 
ATOM   5063 C  CA  . LEU C 1 62  ? -41.101 3.668   23.245  1   47.37  ? 58  LEU C CA  1 
ATOM   5064 C  C   . LEU C 1 62  ? -40.205 4.443   22.269  1   48.22  ? 58  LEU C C   1 
ATOM   5065 O  O   . LEU C 1 62  ? -39.303 5.175   22.674  1   46.37  ? 58  LEU C O   1 
ATOM   5066 C  CB  . LEU C 1 62  ? -41.588 4.542   24.404  1   46.02  ? 58  LEU C CB  1 
ATOM   5067 C  CG  . LEU C 1 62  ? -42.485 3.872   25.454  1   44.48  ? 58  LEU C CG  1 
ATOM   5068 C  CD1 . LEU C 1 62  ? -42.648 4.735   26.687  1   42.91  ? 58  LEU C CD1 1 
ATOM   5069 C  CD2 . LEU C 1 62  ? -43.846 3.5     24.906  1   43.1   ? 58  LEU C CD2 1 
ATOM   5070 N  N   . ASN C 1 63  ? -40.46  4.279   20.963  1   53.08  ? 59  ASN C N   1 
ATOM   5071 C  CA  . ASN C 1 63  ? -39.777 5.056   19.934  1   55.23  ? 59  ASN C CA  1 
ATOM   5072 C  C   . ASN C 1 63  ? -40.815 5.861   19.17   1   55.7   ? 59  ASN C C   1 
ATOM   5073 O  O   . ASN C 1 63  ? -41.604 5.328   18.388  1   59.76  ? 59  ASN C O   1 
ATOM   5074 C  CB  . ASN C 1 63  ? -38.779 4.252   19.103  1   63.27  ? 59  ASN C CB  1 
ATOM   5075 C  CG  . ASN C 1 63  ? -37.529 3.905   19.898  1   75.98  ? 59  ASN C CG  1 
ATOM   5076 O  OD1 . ASN C 1 63  ? -37.224 2.722   20.107  1   79.1   ? 59  ASN C OD1 1 
ATOM   5077 N  ND2 . ASN C 1 63  ? -36.785 4.905   20.362  1   70.2   ? 59  ASN C ND2 1 
ATOM   5078 N  N   . HIS C 1 64  ? -40.836 7.157   19.477  1   55.37  ? 60  HIS C N   1 
ATOM   5079 C  CA  . HIS C 1 64  ? -41.853 8.066   18.971  1   51.44  ? 60  HIS C CA  1 
ATOM   5080 C  C   . HIS C 1 64  ? -41.267 9.468   18.949  1   51.09  ? 60  HIS C C   1 
ATOM   5081 O  O   . HIS C 1 64  ? -40.51  9.85    19.85   1   52.66  ? 60  HIS C O   1 
ATOM   5082 C  CB  . HIS C 1 64  ? -43.118 8.049   19.833  1   49     ? 60  HIS C CB  1 
ATOM   5083 C  CG  . HIS C 1 64  ? -44.247 8.816   19.234  1   57.69  ? 60  HIS C CG  1 
ATOM   5084 N  ND1 . HIS C 1 64  ? -44.435 10.177  19.401  1   61.53  ? 60  HIS C ND1 1 
ATOM   5085 C  CD2 . HIS C 1 64  ? -45.253 8.398   18.448  1   58.21  ? 60  HIS C CD2 1 
ATOM   5086 C  CE1 . HIS C 1 64  ? -45.521 10.552  18.742  1   57.58  ? 60  HIS C CE1 1 
ATOM   5087 N  NE2 . HIS C 1 64  ? -46.031 9.49    18.153  1   57.7   ? 60  HIS C NE2 1 
ATOM   5088 N  N   . PRO C 1 65  ? -41.597 10.274  17.921  1   51.73  ? 61  PRO C N   1 
ATOM   5089 C  CA  . PRO C 1 65  ? -41.057 11.626  17.842  1   48.92  ? 61  PRO C CA  1 
ATOM   5090 C  C   . PRO C 1 65  ? -41.453 12.593  18.96   1   46.62  ? 61  PRO C C   1 
ATOM   5091 O  O   . PRO C 1 65  ? -40.88  13.678  19.013  1   47.77  ? 61  PRO C O   1 
ATOM   5092 C  CB  . PRO C 1 65  ? -41.531 12.073  16.438  1   50.85  ? 61  PRO C CB  1 
ATOM   5093 C  CG  . PRO C 1 65  ? -42.787 11.268  16.18   1   50.51  ? 61  PRO C CG  1 
ATOM   5094 C  CD  . PRO C 1 65  ? -42.451 9.92    16.767  1   52.37  ? 61  PRO C CD  1 
ATOM   5095 N  N   . ASN C 1 66  ? -42.416 12.212  19.823  1   43.79  ? 62  ASN C N   1 
ATOM   5096 C  CA  . ASN C 1 66  ? -42.897 13.06   20.915  1   44.64  ? 62  ASN C CA  1 
ATOM   5097 C  C   . ASN C 1 66  ? -42.588 12.416  22.275  1   47.98  ? 62  ASN C C   1 
ATOM   5098 O  O   . ASN C 1 66  ? -43.207 12.776  23.298  1   41.39  ? 62  ASN C O   1 
ATOM   5099 C  CB  . ASN C 1 66  ? -44.382 13.398  20.805  1   43.57  ? 62  ASN C CB  1 
ATOM   5100 C  CG  . ASN C 1 66  ? -44.703 14.207  19.566  1   49.17  ? 62  ASN C CG  1 
ATOM   5101 O  OD1 . ASN C 1 66  ? -45.607 13.842  18.786  1   50.83  ? 62  ASN C OD1 1 
ATOM   5102 N  ND2 . ASN C 1 66  ? -44.001 15.322  19.389  1   43.83  ? 62  ASN C ND2 1 
ATOM   5103 N  N   . ILE C 1 67  ? -41.65  11.44   22.251  1   42.2   ? 63  ILE C N   1 
ATOM   5104 C  CA  . ILE C 1 67  ? -41.038 10.881  23.445  1   38.4   ? 63  ILE C CA  1 
ATOM   5105 C  C   . ILE C 1 67  ? -39.513 11.026  23.365  1   38.84  ? 63  ILE C C   1 
ATOM   5106 O  O   . ILE C 1 67  ? -38.891 10.641  22.368  1   41.67  ? 63  ILE C O   1 
ATOM   5107 C  CB  . ILE C 1 67  ? -41.468 9.419   23.585  1   35.33  ? 63  ILE C CB  1 
ATOM   5108 C  CG1 . ILE C 1 67  ? -42.949 9.322   23.75   1   35.95  ? 63  ILE C CG1 1 
ATOM   5109 C  CG2 . ILE C 1 67  ? -40.734 8.745   24.741  1   34.57  ? 63  ILE C CG2 1 
ATOM   5110 C  CD1 . ILE C 1 67  ? -43.484 7.917   23.523  1   37.19  ? 63  ILE C CD1 1 
ATOM   5111 N  N   . VAL C 1 68  ? -38.906 11.591  24.417  1   36.84  ? 64  VAL C N   1 
ATOM   5112 C  CA  . VAL C 1 68  ? -37.467 11.802  24.422  1   37.32  ? 64  VAL C CA  1 
ATOM   5113 C  C   . VAL C 1 68  ? -36.76  10.49   24.069  1   39.41  ? 64  VAL C C   1 
ATOM   5114 O  O   . VAL C 1 68  ? -37.154 9.396   24.49   1   39.62  ? 64  VAL C O   1 
ATOM   5115 C  CB  . VAL C 1 68  ? -36.981 12.354  25.772  1   35.94  ? 64  VAL C CB  1 
ATOM   5116 C  CG1 . VAL C 1 68  ? -37.146 11.307  26.86   1   35.44  ? 64  VAL C CG1 1 
ATOM   5117 C  CG2 . VAL C 1 68  ? -35.54  12.865  25.715  1   34.12  ? 64  VAL C CG2 1 
ATOM   5118 N  N   . LYS C 1 69  ? -35.698 10.624  23.281  1   41.22  ? 65  LYS C N   1 
ATOM   5119 C  CA  . LYS C 1 69  ? -34.987 9.488   22.718  1   43.22  ? 65  LYS C CA  1 
ATOM   5120 C  C   . LYS C 1 69  ? -33.836 9.122   23.654  1   40.08  ? 65  LYS C C   1 
ATOM   5121 O  O   . LYS C 1 69  ? -32.99  9.953   24.008  1   38.24  ? 65  LYS C O   1 
ATOM   5122 C  CB  . LYS C 1 69  ? -34.617 9.826   21.266  1   46.95  ? 65  LYS C CB  1 
ATOM   5123 C  CG  . LYS C 1 69  ? -33.99  8.707   20.475  1   57.4   ? 65  LYS C CG  1 
ATOM   5124 C  CD  . LYS C 1 69  ? -34.362 8.78    18.993  1   74.75  ? 65  LYS C CD  1 
ATOM   5125 C  CE  . LYS C 1 69  ? -33.643 7.718   18.177  1   84.53  ? 65  LYS C CE  1 
ATOM   5126 N  NZ  . LYS C 1 69  ? -33.493 6.484   18.964  1   73.87  ? 65  LYS C NZ  1 
ATOM   5127 N  N   . LEU C 1 70  ? -33.872 7.874   24.108  1   37.15  ? 66  LEU C N   1 
ATOM   5128 C  CA  . LEU C 1 70  ? -32.733 7.277   24.769  1   38.48  ? 66  LEU C CA  1 
ATOM   5129 C  C   . LEU C 1 70  ? -31.8   6.705   23.698  1   43.51  ? 66  LEU C C   1 
ATOM   5130 O  O   . LEU C 1 70  ? -32.184 5.806   22.955  1   45.01  ? 66  LEU C O   1 
ATOM   5131 C  CB  . LEU C 1 70  ? -33.297 6.18    25.666  1   36.31  ? 66  LEU C CB  1 
ATOM   5132 C  CG  . LEU C 1 70  ? -32.254 5.393   26.456  1   36.04  ? 66  LEU C CG  1 
ATOM   5133 C  CD1 . LEU C 1 70  ? -31.621 6.33    27.482  1   35.45  ? 66  LEU C CD1 1 
ATOM   5134 C  CD2 . LEU C 1 70  ? -32.932 4.199   27.103  1   37.02  ? 66  LEU C CD2 1 
ATOM   5135 N  N   . LEU C 1 71  ? -30.579 7.248   23.604  1   44.23  ? 67  LEU C N   1 
ATOM   5136 C  CA  . LEU C 1 71  ? -29.65  6.898   22.537  1   40.17  ? 67  LEU C CA  1 
ATOM   5137 C  C   . LEU C 1 71  ? -28.819 5.695   22.975  1   39.26  ? 67  LEU C C   1 
ATOM   5138 O  O   . LEU C 1 71  ? -28.497 4.833   22.145  1   40.45  ? 67  LEU C O   1 
ATOM   5139 C  CB  . LEU C 1 71  ? -28.763 8.102   22.196  1   38.72  ? 67  LEU C CB  1 
ATOM   5140 C  CG  . LEU C 1 71  ? -29.459 9.418   21.83   1   38.04  ? 67  LEU C CG  1 
ATOM   5141 C  CD1 . LEU C 1 71  ? -28.464 10.55   21.758  1   37.05  ? 67  LEU C CD1 1 
ATOM   5142 C  CD2 . LEU C 1 71  ? -30.16  9.303   20.488  1   40.07  ? 67  LEU C CD2 1 
ATOM   5143 N  N   . ASP C 1 72  ? -28.483 5.638   24.282  1   37.5   ? 68  ASP C N   1 
ATOM   5144 C  CA  . ASP C 1 72  ? -27.544 4.63    24.751  1   37.89  ? 68  ASP C CA  1 
ATOM   5145 C  C   . ASP C 1 72  ? -27.563 4.494   26.266  1   37.68  ? 68  ASP C C   1 
ATOM   5146 O  O   . ASP C 1 72  ? -28.112 5.35    26.971  1   37.02  ? 68  ASP C O   1 
ATOM   5147 C  CB  . ASP C 1 72  ? -26.129 5.017   24.375  1   38.52  ? 68  ASP C CB  1 
ATOM   5148 C  CG  . ASP C 1 72  ? -25.119 3.894   24.287  1   37.54  ? 68  ASP C CG  1 
ATOM   5149 O  OD1 . ASP C 1 72  ? -25.426 2.754   24.651  1   36.35  ? 68  ASP C OD1 1 
ATOM   5150 O  OD2 . ASP C 1 72  ? -24.049 4.19    23.786  1   40.63  ? 68  ASP C OD2 1 
ATOM   5151 N  N   . VAL C 1 73  ? -26.946 3.401   26.729  1   37.02  ? 69  VAL C N   1 
ATOM   5152 C  CA  . VAL C 1 73  ? -26.82  3.148   28.151  1   39.48  ? 69  VAL C CA  1 
ATOM   5153 C  C   . VAL C 1 73  ? -25.407 2.624   28.367  1   43.53  ? 69  VAL C C   1 
ATOM   5154 O  O   . VAL C 1 73  ? -25.033 1.625   27.752  1   45.09  ? 69  VAL C O   1 
ATOM   5155 C  CB  . VAL C 1 73  ? -27.905 2.2     28.709  1   37.71  ? 69  VAL C CB  1 
ATOM   5156 C  CG1 . VAL C 1 73  ? -27.646 1.815   30.155  1   35.97  ? 69  VAL C CG1 1 
ATOM   5157 C  CG2 . VAL C 1 73  ? -29.303 2.808   28.591  1   37.55  ? 69  VAL C CG2 1 
ATOM   5158 N  N   . ILE C 1 74  ? -24.603 3.389   29.134  1   46.12  ? 70  ILE C N   1 
ATOM   5159 C  CA  . ILE C 1 74  ? -23.19  3.082   29.337  1   48.14  ? 70  ILE C CA  1 
ATOM   5160 C  C   . ILE C 1 74  ? -23.001 2.555   30.752  1   48.7   ? 70  ILE C C   1 
ATOM   5161 O  O   . ILE C 1 74  ? -23.377 3.221   31.706  1   46.18  ? 70  ILE C O   1 
ATOM   5162 C  CB  . ILE C 1 74  ? -22.271 4.266   28.969  1   47.15  ? 70  ILE C CB  1 
ATOM   5163 C  CG1 . ILE C 1 74  ? -22.312 4.465   27.469  1   46.17  ? 70  ILE C CG1 1 
ATOM   5164 C  CG2 . ILE C 1 74  ? -20.824 4.025   29.404  1   47.79  ? 70  ILE C CG2 1 
ATOM   5165 C  CD1 . ILE C 1 74  ? -22.201 5.901   27.038  1   45.85  ? 70  ILE C CD1 1 
ATOM   5166 N  N   . HIS C 1 75  ? -22.439 1.342   30.856  1   53.17  ? 71  HIS C N   1 
ATOM   5167 C  CA  . HIS C 1 75  ? -22.333 0.67    32.145  1   60.73  ? 71  HIS C CA  1 
ATOM   5168 C  C   . HIS C 1 75  ? -20.873 0.686   32.557  1   58.8   ? 71  HIS C C   1 
ATOM   5169 O  O   . HIS C 1 75  ? -19.994 0.497   31.726  1   61.6   ? 71  HIS C O   1 
ATOM   5170 C  CB  . HIS C 1 75  ? -22.678 -0.835  32.133  1   64.35  ? 71  HIS C CB  1 
ATOM   5171 C  CG  . HIS C 1 75  ? -23.931 -1.251  31.454  1   66.45  ? 71  HIS C CG  1 
ATOM   5172 N  ND1 . HIS C 1 75  ? -24.208 -0.929  30.141  1   73.96  ? 71  HIS C ND1 1 
ATOM   5173 C  CD2 . HIS C 1 75  ? -24.958 -1.976  31.889  1   69.27  ? 71  HIS C CD2 1 
ATOM   5174 C  CE1 . HIS C 1 75  ? -25.386 -1.429  29.805  1   73.24  ? 71  HIS C CE1 1 
ATOM   5175 N  NE2 . HIS C 1 75  ? -25.863 -2.059  30.86   1   76.63  ? 71  HIS C NE2 1 
ATOM   5176 N  N   . THR C 1 76  ? -20.642 0.939   33.84   1   55.77  ? 72  THR C N   1 
ATOM   5177 C  CA  . THR C 1 76  ? -19.354 0.654   34.432  1   58.67  ? 72  THR C CA  1 
ATOM   5178 C  C   . THR C 1 76  ? -19.652 -0.293  35.581  1   59.04  ? 72  THR C C   1 
ATOM   5179 O  O   . THR C 1 76  ? -20.818 -0.57   35.853  1   57.11  ? 72  THR C O   1 
ATOM   5180 C  CB  . THR C 1 76  ? -18.679 1.964   34.846  1   59.89  ? 72  THR C CB  1 
ATOM   5181 O  OG1 . THR C 1 76  ? -19.406 2.625   35.89   1   62.65  ? 72  THR C OG1 1 
ATOM   5182 C  CG2 . THR C 1 76  ? -18.485 2.873   33.642  1   55.3   ? 72  THR C CG2 1 
ATOM   5183 N  N   . GLU C 1 77  ? -18.604 -0.777  36.239  1   63.34  ? 73  GLU C N   1 
ATOM   5184 C  CA  . GLU C 1 77  ? -18.771 -1.586  37.431  1   63.06  ? 73  GLU C CA  1 
ATOM   5185 C  C   . GLU C 1 77  ? -19.528 -0.802  38.504  1   60.57  ? 73  GLU C C   1 
ATOM   5186 O  O   . GLU C 1 77  ? -20.282 -1.411  39.256  1   58.77  ? 73  GLU C O   1 
ATOM   5187 C  CB  . GLU C 1 77  ? -17.422 -2.124  37.904  1   67.36  ? 73  GLU C CB  1 
ATOM   5188 C  CG  . GLU C 1 77  ? -17.593 -3.22   38.948  1   73.68  ? 73  GLU C CG  1 
ATOM   5189 C  CD  . GLU C 1 77  ? -16.372 -3.369  39.834  1   83.14  ? 73  GLU C CD  1 
ATOM   5190 O  OE1 . GLU C 1 77  ? -16.507 -3.119  41.06   1   84.06  ? 73  GLU C OE1 1 
ATOM   5191 O  OE2 . GLU C 1 77  ? -15.29  -3.715  39.296  1   87.06  ? 73  GLU C OE2 1 
ATOM   5192 N  N   . ASN C 1 78  ? -19.349 0.518   38.549  1   62.27  ? 74  ASN C N   1 
ATOM   5193 C  CA  . ASN C 1 78  ? -19.918 1.309   39.676  1   59.98  ? 74  ASN C CA  1 
ATOM   5194 C  C   . ASN C 1 78  ? -20.903 2.403   39.243  1   55.79  ? 74  ASN C C   1 
ATOM   5195 O  O   . ASN C 1 78  ? -21.506 3.001   40.142  1   58.28  ? 74  ASN C O   1 
ATOM   5196 C  CB  . ASN C 1 78  ? -18.785 1.92    40.494  1   60.77  ? 74  ASN C CB  1 
ATOM   5197 C  CG  . ASN C 1 78  ? -18.041 0.891   41.307  1   61.94  ? 74  ASN C CG  1 
ATOM   5198 O  OD1 . ASN C 1 78  ? -16.976 0.425   40.892  1   62.61  ? 74  ASN C OD1 1 
ATOM   5199 N  ND2 . ASN C 1 78  ? -18.573 0.533   42.465  1   61.3   ? 74  ASN C ND2 1 
ATOM   5200 N  N   . LYS C 1 79  ? -21.052 2.682   37.95   1   53.58  ? 75  LYS C N   1 
ATOM   5201 C  CA  . LYS C 1 79  ? -21.936 3.804   37.537  1   51.02  ? 75  LYS C CA  1 
ATOM   5202 C  C   . LYS C 1 79  ? -22.766 3.433   36.305  1   47.22  ? 75  LYS C C   1 
ATOM   5203 O  O   . LYS C 1 79  ? -22.355 2.55    35.546  1   52.09  ? 75  LYS C O   1 
ATOM   5204 C  CB  . LYS C 1 79  ? -21.155 5.079   37.207  1   54.26  ? 75  LYS C CB  1 
ATOM   5205 C  CG  . LYS C 1 79  ? -20.367 5.7     38.339  1   64.17  ? 75  LYS C CG  1 
ATOM   5206 C  CD  . LYS C 1 79  ? -19.156 6.484   37.854  1   71.7   ? 75  LYS C CD  1 
ATOM   5207 C  CE  . LYS C 1 79  ? -18.326 5.69    36.902  1   76.7   ? 75  LYS C CE  1 
ATOM   5208 N  NZ  . LYS C 1 79  ? -17.767 4.501   37.548  1   78.99  ? 75  LYS C NZ  1 
ATOM   5209 N  N   . LEU C 1 80  ? -23.896 4.101   36.128  1   43.16  ? 76  LEU C N   1 
ATOM   5210 C  CA  . LEU C 1 80  ? -24.75  3.866   34.944  1   43.77  ? 76  LEU C CA  1 
ATOM   5211 C  C   . LEU C 1 80  ? -25.03  5.221   34.296  1   46.96  ? 76  LEU C C   1 
ATOM   5212 O  O   . LEU C 1 80  ? -25.338 6.175   35.021  1   46.36  ? 76  LEU C O   1 
ATOM   5213 C  CB  . LEU C 1 80  ? -26.044 3.18    35.362  1   43.67  ? 76  LEU C CB  1 
ATOM   5214 C  CG  . LEU C 1 80  ? -26.785 2.4     34.276  1   42.45  ? 76  LEU C CG  1 
ATOM   5215 C  CD1 . LEU C 1 80  ? -25.91  1.278   33.757  1   43.56  ? 76  LEU C CD1 1 
ATOM   5216 C  CD2 . LEU C 1 80  ? -28.053 1.849   34.888  1   41.63  ? 76  LEU C CD2 1 
ATOM   5217 N  N   . TYR C 1 81  ? -24.93  5.289   32.975  1   46.51  ? 77  TYR C N   1 
ATOM   5218 C  CA  . TYR C 1 81  ? -25.118 6.592   32.301  1   46.71  ? 77  TYR C CA  1 
ATOM   5219 C  C   . TYR C 1 81  ? -26.127 6.479   31.194  1   43.6   ? 77  TYR C C   1 
ATOM   5220 O  O   . TYR C 1 81  ? -25.877 5.768   30.214  1   44.87  ? 77  TYR C O   1 
ATOM   5221 C  CB  . TYR C 1 81  ? -23.797 7.078   31.705  1   50.24  ? 77  TYR C CB  1 
ATOM   5222 C  CG  . TYR C 1 81  ? -22.725 7.563   32.667  1   51.83  ? 77  TYR C CG  1 
ATOM   5223 C  CD1 . TYR C 1 81  ? -22.688 8.882   33.092  1   53.64  ? 77  TYR C CD1 1 
ATOM   5224 C  CD2 . TYR C 1 81  ? -21.728 6.707   33.113  1   56.59  ? 77  TYR C CD2 1 
ATOM   5225 C  CE1 . TYR C 1 81  ? -21.7   9.333   33.95   1   58.53  ? 77  TYR C CE1 1 
ATOM   5226 C  CE2 . TYR C 1 81  ? -20.738 7.144   33.973  1   60.89  ? 77  TYR C CE2 1 
ATOM   5227 C  CZ  . TYR C 1 81  ? -20.724 8.46    34.393  1   61.54  ? 77  TYR C CZ  1 
ATOM   5228 O  OH  . TYR C 1 81  ? -19.748 8.888   35.241  1   72.42  ? 77  TYR C OH  1 
ATOM   5229 N  N   . LEU C 1 82  ? -27.268 7.139   31.354  1   39.57  ? 78  LEU C N   1 
ATOM   5230 C  CA  . LEU C 1 82  ? -28.199 7.217   30.251  1   39.73  ? 78  LEU C CA  1 
ATOM   5231 C  C   . LEU C 1 82  ? -27.811 8.379   29.334  1   39.81  ? 78  LEU C C   1 
ATOM   5232 O  O   . LEU C 1 82  ? -27.707 9.512   29.791  1   36.83  ? 78  LEU C O   1 
ATOM   5233 C  CB  . LEU C 1 82  ? -29.586 7.406   30.849  1   42.13  ? 78  LEU C CB  1 
ATOM   5234 C  CG  . LEU C 1 82  ? -30.246 6.172   31.478  1   43.94  ? 78  LEU C CG  1 
ATOM   5235 C  CD1 . LEU C 1 82  ? -29.506 5.634   32.677  1   46.06  ? 78  LEU C CD1 1 
ATOM   5236 C  CD2 . LEU C 1 82  ? -31.678 6.498   31.848  1   43.81  ? 78  LEU C CD2 1 
ATOM   5237 N  N   . VAL C 1 83  ? -27.603 8.081   28.045  1   38.03  ? 79  VAL C N   1 
ATOM   5238 C  CA  . VAL C 1 83  ? -27.368 9.091   27.029  1   36.66  ? 79  VAL C CA  1 
ATOM   5239 C  C   . VAL C 1 83  ? -28.697 9.362   26.333  1   36.47  ? 79  VAL C C   1 
ATOM   5240 O  O   . VAL C 1 83  ? -29.268 8.458   25.723  1   38.08  ? 79  VAL C O   1 
ATOM   5241 C  CB  . VAL C 1 83  ? -26.309 8.628   26.008  1   37.82  ? 79  VAL C CB  1 
ATOM   5242 C  CG1 . VAL C 1 83  ? -25.842 9.758   25.089  1   36.69  ? 79  VAL C CG1 1 
ATOM   5243 C  CG2 . VAL C 1 83  ? -25.117 7.977   26.683  1   35.84  ? 79  VAL C CG2 1 
ATOM   5244 N  N   . PHE C 1 84  ? -29.18  10.614  26.439  1   36.5   ? 80  PHE C N   1 
ATOM   5245 C  CA  . PHE C 1 84  ? -30.415 11.081  25.814  1   34.87  ? 80  PHE C CA  1 
ATOM   5246 C  C   . PHE C 1 84  ? -30.116 12.115  24.723  1   35.99  ? 80  PHE C C   1 
ATOM   5247 O  O   . PHE C 1 84  ? -29.082 12.784  24.755  1   37.05  ? 80  PHE C O   1 
ATOM   5248 C  CB  . PHE C 1 84  ? -31.284 11.772  26.863  1   33.98  ? 80  PHE C CB  1 
ATOM   5249 C  CG  . PHE C 1 84  ? -31.98  10.885  27.885  1   34.1   ? 80  PHE C CG  1 
ATOM   5250 C  CD1 . PHE C 1 84  ? -33.162 10.219  27.556  1   33.02  ? 80  PHE C CD1 1 
ATOM   5251 C  CD2 . PHE C 1 84  ? -31.456 10.725  29.174  1   34.51  ? 80  PHE C CD2 1 
ATOM   5252 C  CE1 . PHE C 1 84  ? -33.797 9.415   28.491  1   33.65  ? 80  PHE C CE1 1 
ATOM   5253 C  CE2 . PHE C 1 84  ? -32.091 9.906   30.106  1   32.42  ? 80  PHE C CE2 1 
ATOM   5254 C  CZ  . PHE C 1 84  ? -33.267 9.267   29.77   1   32.51  ? 80  PHE C CZ  1 
ATOM   5255 N  N   . GLU C 1 85  ? -31.021 12.253  23.748  1   35.63  ? 81  GLU C N   1 
ATOM   5256 C  CA  . GLU C 1 85  ? -30.916 13.381  22.844  1   36.77  ? 81  GLU C CA  1 
ATOM   5257 C  C   . GLU C 1 85  ? -31.073 14.642  23.693  1   40.39  ? 81  GLU C C   1 
ATOM   5258 O  O   . GLU C 1 85  ? -31.869 14.668  24.637  1   40.24  ? 81  GLU C O   1 
ATOM   5259 C  CB  . GLU C 1 85  ? -31.989 13.305  21.758  1   37.4   ? 81  GLU C CB  1 
ATOM   5260 C  CG  . GLU C 1 85  ? -33.416 13.509  22.272  1   39.02  ? 81  GLU C CG  1 
ATOM   5261 C  CD  . GLU C 1 85  ? -34.589 13.402  21.306  1   42.37  ? 81  GLU C CD  1 
ATOM   5262 O  OE1 . GLU C 1 85  ? -34.515 13.987  20.209  1   43.71  ? 81  GLU C OE1 1 
ATOM   5263 O  OE2 . GLU C 1 85  ? -35.602 12.769  21.667  1   45.66  ? 81  GLU C OE2 1 
ATOM   5264 N  N   . PHE C 1 86  ? -30.311 15.691  23.359  1   41.98  ? 82  PHE C N   1 
ATOM   5265 C  CA  . PHE C 1 86  ? -30.43  16.973  24.031  1   40.03  ? 82  PHE C CA  1 
ATOM   5266 C  C   . PHE C 1 86  ? -31.579 17.767  23.412  1   42.39  ? 82  PHE C C   1 
ATOM   5267 O  O   . PHE C 1 86  ? -31.636 17.932  22.198  1   41.14  ? 82  PHE C O   1 
ATOM   5268 C  CB  . PHE C 1 86  ? -29.128 17.762  23.895  1   39.5   ? 82  PHE C CB  1 
ATOM   5269 C  CG  . PHE C 1 86  ? -29.26  19.17   24.435  1   40.44  ? 82  PHE C CG  1 
ATOM   5270 C  CD1 . PHE C 1 86  ? -29.297 19.398  25.806  1   39.56  ? 82  PHE C CD1 1 
ATOM   5271 C  CD2 . PHE C 1 86  ? -29.397 20.261  23.575  1   43.08  ? 82  PHE C CD2 1 
ATOM   5272 C  CE1 . PHE C 1 86  ? -29.445 20.688  26.31   1   39.17  ? 82  PHE C CE1 1 
ATOM   5273 C  CE2 . PHE C 1 86  ? -29.539 21.558  24.084  1   43.31  ? 82  PHE C CE2 1 
ATOM   5274 C  CZ  . PHE C 1 86  ? -29.55  21.766  25.455  1   40.07  ? 82  PHE C CZ  1 
ATOM   5275 N  N   . LEU C 1 87  ? -32.503 18.243  24.26   1   42.35  ? 83  LEU C N   1 
ATOM   5276 C  CA  . LEU C 1 87  ? -33.474 19.231  23.834  1   42.91  ? 83  LEU C CA  1 
ATOM   5277 C  C   . LEU C 1 87  ? -33.265 20.501  24.648  1   44.33  ? 83  LEU C C   1 
ATOM   5278 O  O   . LEU C 1 87  ? -32.859 20.438  25.809  1   43.64  ? 83  LEU C O   1 
ATOM   5279 C  CB  . LEU C 1 87  ? -34.918 18.76   23.9    1   43.49  ? 83  LEU C CB  1 
ATOM   5280 C  CG  . LEU C 1 87  ? -35.324 17.736  22.847  1   45.29  ? 83  LEU C CG  1 
ATOM   5281 C  CD1 . LEU C 1 87  ? -35.306 16.371  23.488  1   46.37  ? 83  LEU C CD1 1 
ATOM   5282 C  CD2 . LEU C 1 87  ? -36.731 18.079  22.472  1   48.5   ? 83  LEU C CD2 1 
ATOM   5283 N  N   . HIS C 1 88  ? -33.577 21.63   24.004  1   47.32  ? 84  HIS C N   1 
ATOM   5284 C  CA  . HIS C 1 88  ? -33.09  22.961  24.337  1   53.69  ? 84  HIS C CA  1 
ATOM   5285 C  C   . HIS C 1 88  ? -33.481 23.389  25.758  1   52.71  ? 84  HIS C C   1 
ATOM   5286 O  O   . HIS C 1 88  ? -32.689 24.036  26.458  1   47.89  ? 84  HIS C O   1 
ATOM   5287 C  CB  . HIS C 1 88  ? -33.537 23.935  23.247  1   58.39  ? 84  HIS C CB  1 
ATOM   5288 C  CG  . HIS C 1 88  ? -33.349 25.353  23.628  1   67.57  ? 84  HIS C CG  1 
ATOM   5289 N  ND1 . HIS C 1 88  ? -34.419 26.161  23.947  1   77.78  ? 84  HIS C ND1 1 
ATOM   5290 C  CD2 . HIS C 1 88  ? -32.254 26.121  23.724  1   75.28  ? 84  HIS C CD2 1 
ATOM   5291 C  CE1 . HIS C 1 88  ? -33.981 27.379  24.257  1   77.38  ? 84  HIS C CE1 1 
ATOM   5292 N  NE2 . HIS C 1 88  ? -32.666 27.378  24.12   1   79.19  ? 84  HIS C NE2 1 
ATOM   5293 N  N   . GLN C 1 89  ? -34.722 23.054  26.151  1   50.42  ? 85  GLN C N   1 
ATOM   5294 C  CA  . GLN C 1 89  ? -35.202 23.278  27.506  1   46.76  ? 85  GLN C CA  1 
ATOM   5295 C  C   . GLN C 1 89  ? -36.584 22.664  27.709  1   43.48  ? 85  GLN C C   1 
ATOM   5296 O  O   . GLN C 1 89  ? -37.142 22.04   26.792  1   43.75  ? 85  GLN C O   1 
ATOM   5297 C  CB  . GLN C 1 89  ? -35.329 24.761  27.83   1   50     ? 85  GLN C CB  1 
ATOM   5298 C  CG  . GLN C 1 89  ? -36.349 25.497  26.968  1   50.91  ? 85  GLN C CG  1 
ATOM   5299 C  CD  . GLN C 1 89  ? -36.4   26.948  27.369  1   55.02  ? 85  GLN C CD  1 
ATOM   5300 O  OE1 . GLN C 1 89  ? -35.719 27.372  28.313  1   58.9   ? 85  GLN C OE1 1 
ATOM   5301 N  NE2 . GLN C 1 89  ? -37.212 27.711  26.664  1   56.33  ? 85  GLN C NE2 1 
ATOM   5302 N  N   . ASP C 1 90  ? -37.092 22.849  28.939  1   39.31  ? 86  ASP C N   1 
ATOM   5303 C  CA  . ASP C 1 90  ? -38.36  22.311  29.384  1   40.77  ? 86  ASP C CA  1 
ATOM   5304 C  C   . ASP C 1 90  ? -39.463 23.371  29.272  1   43.46  ? 86  ASP C C   1 
ATOM   5305 O  O   . ASP C 1 90  ? -39.194 24.584  29.283  1   45.22  ? 86  ASP C O   1 
ATOM   5306 C  CB  . ASP C 1 90  ? -38.25  21.709  30.779  1   40.72  ? 86  ASP C CB  1 
ATOM   5307 C  CG  . ASP C 1 90  ? -37.922 22.697  31.882  1   43.86  ? 86  ASP C CG  1 
ATOM   5308 O  OD1 . ASP C 1 90  ? -38.712 23.634  32.094  1   45.96  ? 86  ASP C OD1 1 
ATOM   5309 O  OD2 . ASP C 1 90  ? -36.876 22.529  32.527  1   51.66  ? 86  ASP C OD2 1 
ATOM   5310 N  N   . LEU C 1 91  ? -40.713 22.875  29.225  1   39.4   ? 87  LEU C N   1 
ATOM   5311 C  CA  . LEU C 1 91  ? -41.901 23.69   29.064  1   38.87  ? 87  LEU C CA  1 
ATOM   5312 C  C   . LEU C 1 91  ? -42.013 24.686  30.224  1   39.24  ? 87  LEU C C   1 
ATOM   5313 O  O   . LEU C 1 91  ? -42.4   25.823  30.006  1   38.47  ? 87  LEU C O   1 
ATOM   5314 C  CB  . LEU C 1 91  ? -43.115 22.77   28.911  1   36.32  ? 87  LEU C CB  1 
ATOM   5315 C  CG  . LEU C 1 91  ? -44.467 23.454  28.681  1   37.18  ? 87  LEU C CG  1 
ATOM   5316 C  CD1 . LEU C 1 91  ? -44.429 24.276  27.406  1   39.36  ? 87  LEU C CD1 1 
ATOM   5317 C  CD2 . LEU C 1 91  ? -45.613 22.466  28.605  1   35.09  ? 87  LEU C CD2 1 
ATOM   5318 N  N   . LYS C 1 92  ? -41.65  24.27   31.445  1   38.61  ? 88  LYS C N   1 
ATOM   5319 C  CA  . LYS C 1 92  ? -41.68  25.163  32.592  1   38.74  ? 88  LYS C CA  1 
ATOM   5320 C  C   . LYS C 1 92  ? -40.883 26.443  32.324  1   41.71  ? 88  LYS C C   1 
ATOM   5321 O  O   . LYS C 1 92  ? -41.404 27.536  32.526  1   45.96  ? 88  LYS C O   1 
ATOM   5322 C  CB  . LYS C 1 92  ? -41.37  24.424  33.898  1   37.81  ? 88  LYS C CB  1 
ATOM   5323 C  CG  . LYS C 1 92  ? -41.247 25.24   35.188  1   40.19  ? 88  LYS C CG  1 
ATOM   5324 C  CD  . LYS C 1 92  ? -42.187 26.404  35.509  1   47.19  ? 88  LYS C CD  1 
ATOM   5325 C  CE  . LYS C 1 92  ? -43.646 26.045  35.573  1   53.44  ? 88  LYS C CE  1 
ATOM   5326 N  NZ  . LYS C 1 92  ? -44.553 27.189  35.753  1   55.11  ? 88  LYS C NZ  1 
ATOM   5327 N  N   . LYS C 1 93  ? -39.648 26.334  31.825  1   42.58  ? 89  LYS C N   1 
ATOM   5328 C  CA  . LYS C 1 93  ? -38.82  27.525  31.661  1   44.96  ? 89  LYS C CA  1 
ATOM   5329 C  C   . LYS C 1 93  ? -39.355 28.41   30.536  1   43.72  ? 89  LYS C C   1 
ATOM   5330 O  O   . LYS C 1 93  ? -39.295 29.638  30.628  1   43.04  ? 89  LYS C O   1 
ATOM   5331 C  CB  . LYS C 1 93  ? -37.349 27.211  31.358  1   50.28  ? 89  LYS C CB  1 
ATOM   5332 C  CG  . LYS C 1 93  ? -36.658 26.342  32.394  1   56.36  ? 89  LYS C CG  1 
ATOM   5333 C  CD  . LYS C 1 93  ? -35.153 26.579  32.432  1   65.15  ? 89  LYS C CD  1 
ATOM   5334 C  CE  . LYS C 1 93  ? -34.43  25.694  33.406  1   68.07  ? 89  LYS C CE  1 
ATOM   5335 N  NZ  . LYS C 1 93  ? -33.011 26.054  33.424  1   71.75  ? 89  LYS C NZ  1 
ATOM   5336 N  N   . PHE C 1 94  ? -39.857 27.772  29.472  1   41.2   ? 90  PHE C N   1 
ATOM   5337 C  CA  . PHE C 1 94  ? -40.466 28.48   28.362  1   42.93  ? 90  PHE C CA  1 
ATOM   5338 C  C   . PHE C 1 94  ? -41.661 29.3    28.848  1   46.03  ? 90  PHE C C   1 
ATOM   5339 O  O   . PHE C 1 94  ? -41.778 30.497  28.514  1   47.16  ? 90  PHE C O   1 
ATOM   5340 C  CB  . PHE C 1 94  ? -40.938 27.472  27.316  1   42.12  ? 90  PHE C CB  1 
ATOM   5341 C  CG  . PHE C 1 94  ? -41.555 28.126  26.089  1   43.66  ? 90  PHE C CG  1 
ATOM   5342 C  CD1 . PHE C 1 94  ? -40.781 28.928  25.251  1   43.98  ? 90  PHE C CD1 1 
ATOM   5343 C  CD2 . PHE C 1 94  ? -42.892 27.906  25.753  1   43.71  ? 90  PHE C CD2 1 
ATOM   5344 C  CE1 . PHE C 1 94  ? -41.338 29.517  24.129  1   45.42  ? 90  PHE C CE1 1 
ATOM   5345 C  CE2 . PHE C 1 94  ? -43.432 28.464  24.603  1   43.23  ? 90  PHE C CE2 1 
ATOM   5346 C  CZ  . PHE C 1 94  ? -42.653 29.269  23.805  1   44.36  ? 90  PHE C CZ  1 
ATOM   5347 N  N   . MET C 1 95  ? -42.531 28.632  29.634  1   43.07  ? 91  MET C N   1 
ATOM   5348 C  CA  . MET C 1 95  ? -43.655 29.278  30.29   1   41.17  ? 91  MET C CA  1 
ATOM   5349 C  C   . MET C 1 95  ? -43.175 30.489  31.081  1   41.98  ? 91  MET C C   1 
ATOM   5350 O  O   . MET C 1 95  ? -43.677 31.583  30.846  1   46.6   ? 91  MET C O   1 
ATOM   5351 C  CB  . MET C 1 95  ? -44.497 28.298  31.1    1   40.5   ? 91  MET C CB  1 
ATOM   5352 C  CG  . MET C 1 95  ? -45.397 27.436  30.241  1   44.51  ? 91  MET C CG  1 
ATOM   5353 S  SD  . MET C 1 95  ? -46.249 26.074  31.075  1   50.12  ? 91  MET C SD  1 
ATOM   5354 C  CE  . MET C 1 95  ? -45.191 25.809  32.498  1   48.16  ? 91  MET C CE  1 
ATOM   5355 N  N   . ASP C 1 96  ? -42.154 30.329  31.933  1   41.39  ? 92  ASP C N   1 
ATOM   5356 C  CA  . ASP C 1 96  ? -41.655 31.462  32.717  1   42.12  ? 92  ASP C CA  1 
ATOM   5357 C  C   . ASP C 1 96  ? -41.133 32.55   31.785  1   43.38  ? 92  ASP C C   1 
ATOM   5358 O  O   . ASP C 1 96  ? -41.361 33.721  32.028  1   47.11  ? 92  ASP C O   1 
ATOM   5359 C  CB  . ASP C 1 96  ? -40.609 31.062  33.749  1   40.95  ? 92  ASP C CB  1 
ATOM   5360 C  CG  . ASP C 1 96  ? -41.139 30.203  34.889  1   41.67  ? 92  ASP C CG  1 
ATOM   5361 O  OD1 . ASP C 1 96  ? -42.343 30.335  35.189  1   41.91  ? 92  ASP C OD1 1 
ATOM   5362 O  OD2 . ASP C 1 96  ? -40.369 29.378  35.443  1   41.26  ? 92  ASP C OD2 1 
ATOM   5363 N  N   . ALA C 1 97  ? -40.424 32.172  30.719  1   44.1   ? 93  ALA C N   1 
ATOM   5364 C  CA  . ALA C 1 97  ? -39.879 33.179  29.823  1   46.74  ? 93  ALA C CA  1 
ATOM   5365 C  C   . ALA C 1 97  ? -41.034 33.91   29.152  1   48.56  ? 93  ALA C C   1 
ATOM   5366 O  O   . ALA C 1 97  ? -40.88  35.063  28.762  1   49.28  ? 93  ALA C O   1 
ATOM   5367 C  CB  . ALA C 1 97  ? -38.944 32.569  28.793  1   44.35  ? 93  ALA C CB  1 
ATOM   5368 N  N   . SER C 1 98  ? -42.186 33.233  29.05   1   49.63  ? 94  SER C N   1 
ATOM   5369 C  CA  . SER C 1 98  ? -43.352 33.763  28.355  1   49.63  ? 94  SER C CA  1 
ATOM   5370 C  C   . SER C 1 98  ? -44.398 34.322  29.32   1   48.69  ? 94  SER C C   1 
ATOM   5371 O  O   . SER C 1 98  ? -45.549 34.519  28.93   1   51.25  ? 94  SER C O   1 
ATOM   5372 C  CB  . SER C 1 98  ? -43.966 32.71   27.466  1   49.37  ? 94  SER C CB  1 
ATOM   5373 O  OG  . SER C 1 98  ? -43.11  32.423  26.372  1   51.06  ? 94  SER C OG  1 
ATOM   5374 N  N   . ALA C 1 99  ? -44.008 34.575  30.57   1   47.1   ? 95  ALA C N   1 
ATOM   5375 C  CA  . ALA C 1 99  ? -44.912 35.081  31.603  1   47.68  ? 95  ALA C CA  1 
ATOM   5376 C  C   . ALA C 1 99  ? -45.541 36.423  31.22   1   49.15  ? 95  ALA C C   1 
ATOM   5377 O  O   . ALA C 1 99  ? -46.691 36.688  31.568  1   51.09  ? 95  ALA C O   1 
ATOM   5378 C  CB  . ALA C 1 99  ? -44.162 35.211  32.922  1   49.31  ? 95  ALA C CB  1 
ATOM   5379 N  N   . LEU C 1 100 ? -44.774 37.294  30.555  1   49     ? 96  LEU C N   1 
ATOM   5380 C  CA  . LEU C 1 100 ? -45.301 38.592  30.167  1   51.36  ? 96  LEU C CA  1 
ATOM   5381 C  C   . LEU C 1 100 ? -45.873 38.561  28.743  1   56.97  ? 96  LEU C C   1 
ATOM   5382 O  O   . LEU C 1 100 ? -47.013 38.974  28.567  1   59.19  ? 96  LEU C O   1 
ATOM   5383 C  CB  . LEU C 1 100 ? -44.291 39.713  30.411  1   48.26  ? 96  LEU C CB  1 
ATOM   5384 C  CG  . LEU C 1 100 ? -43.718 39.766  31.832  1   45.52  ? 96  LEU C CG  1 
ATOM   5385 C  CD1 . LEU C 1 100 ? -42.758 40.916  32.08   1   45.44  ? 96  LEU C CD1 1 
ATOM   5386 C  CD2 . LEU C 1 100 ? -44.821 39.751  32.868  1   43.71  ? 96  LEU C CD2 1 
ATOM   5387 N  N   . THR C 1 101 ? -45.112 38.058  27.743  1   59.98  ? 97  THR C N   1 
ATOM   5388 C  CA  . THR C 1 101 ? -45.485 38.065  26.326  1   60.82  ? 97  THR C CA  1 
ATOM   5389 C  C   . THR C 1 101 ? -46.727 37.205  26.09   1   59.14  ? 97  THR C C   1 
ATOM   5390 O  O   . THR C 1 101 ? -47.658 37.623  25.415  1   61.32  ? 97  THR C O   1 
ATOM   5391 C  CB  . THR C 1 101 ? -44.343 37.609  25.405  1   64.44  ? 97  THR C CB  1 
ATOM   5392 O  OG1 . THR C 1 101 ? -44.245 36.186  25.475  1   65.71  ? 97  THR C OG1 1 
ATOM   5393 C  CG2 . THR C 1 101 ? -43     38.251  25.717  1   66.52  ? 97  THR C CG2 1 
ATOM   5394 N  N   . GLY C 1 102 ? -46.729 35.987  26.635  1   56.16  ? 98  GLY C N   1 
ATOM   5395 C  CA  . GLY C 1 102 ? -47.765 35.012  26.336  1   54.83  ? 98  GLY C CA  1 
ATOM   5396 C  C   . GLY C 1 102 ? -47.227 33.94   25.391  1   54.2   ? 98  GLY C C   1 
ATOM   5397 O  O   . GLY C 1 102 ? -46.179 34.135  24.762  1   53.83  ? 98  GLY C O   1 
ATOM   5398 N  N   . ILE C 1 103 ? -47.928 32.795  25.333  1   51.27  ? 99  ILE C N   1 
ATOM   5399 C  CA  . ILE C 1 103 ? -47.637 31.774  24.332  1   51.59  ? 99  ILE C CA  1 
ATOM   5400 C  C   . ILE C 1 103 ? -48.73  31.867  23.274  1   53.3   ? 99  ILE C C   1 
ATOM   5401 O  O   . ILE C 1 103 ? -49.917 31.841  23.609  1   54.34  ? 99  ILE C O   1 
ATOM   5402 C  CB  . ILE C 1 103 ? -47.552 30.349  24.912  1   49.76  ? 99  ILE C CB  1 
ATOM   5403 C  CG1 . ILE C 1 103 ? -46.575 30.229  26.11   1   48.01  ? 99  ILE C CG1 1 
ATOM   5404 C  CG2 . ILE C 1 103 ? -47.229 29.339  23.806  1   49.67  ? 99  ILE C CG2 1 
ATOM   5405 C  CD1 . ILE C 1 103 ? -46.539 28.832  26.726  1   44.71  ? 99  ILE C CD1 1 
ATOM   5406 N  N   . PRO C 1 104 ? -48.358 32.055  21.987  1   54.11  ? 100 PRO C N   1 
ATOM   5407 C  CA  . PRO C 1 104 ? -49.343 32.223  20.912  1   55.3   ? 100 PRO C CA  1 
ATOM   5408 C  C   . PRO C 1 104 ? -50.237 30.985  20.882  1   55.95  ? 100 PRO C C   1 
ATOM   5409 O  O   . PRO C 1 104 ? -49.761 29.885  21.138  1   51.2   ? 100 PRO C O   1 
ATOM   5410 C  CB  . PRO C 1 104 ? -48.451 32.327  19.653  1   56.62  ? 100 PRO C CB  1 
ATOM   5411 C  CG  . PRO C 1 104 ? -47.097 32.8    20.158  1   54.8   ? 100 PRO C CG  1 
ATOM   5412 C  CD  . PRO C 1 104 ? -46.961 32.14   21.524  1   53.51  ? 100 PRO C CD  1 
ATOM   5413 N  N   . LEU C 1 105 ? -51.532 31.16   20.577  1   60.95  ? 101 LEU C N   1 
ATOM   5414 C  CA  . LEU C 1 105 ? -52.459 30.037  20.645  1   63.07  ? 101 LEU C CA  1 
ATOM   5415 C  C   . LEU C 1 105 ? -52.07  28.92   19.668  1   62.86  ? 101 LEU C C   1 
ATOM   5416 O  O   . LEU C 1 105 ? -52.109 27.749  20.042  1   60.47  ? 101 LEU C O   1 
ATOM   5417 C  CB  . LEU C 1 105 ? -53.941 30.392  20.554  1   66.21  ? 101 LEU C CB  1 
ATOM   5418 C  CG  . LEU C 1 105 ? -54.885 29.234  20.9    1   69.2   ? 101 LEU C CG  1 
ATOM   5419 C  CD1 . LEU C 1 105 ? -54.831 28.953  22.402  1   67.04  ? 101 LEU C CD1 1 
ATOM   5420 C  CD2 . LEU C 1 105 ? -56.33  29.465  20.472  1   73.78  ? 101 LEU C CD2 1 
ATOM   5421 N  N   . PRO C 1 106 ? -51.723 29.207  18.387  1   63.78  ? 102 PRO C N   1 
ATOM   5422 C  CA  . PRO C 1 106 ? -51.095 28.203  17.527  1   62.82  ? 102 PRO C CA  1 
ATOM   5423 C  C   . PRO C 1 106 ? -50.098 27.26   18.21   1   63.29  ? 102 PRO C C   1 
ATOM   5424 O  O   . PRO C 1 106 ? -50.193 26.035  18.076  1   65.92  ? 102 PRO C O   1 
ATOM   5425 C  CB  . PRO C 1 106 ? -50.429 29.12   16.476  1   65.13  ? 102 PRO C CB  1 
ATOM   5426 C  CG  . PRO C 1 106 ? -51.436 30.219  16.264  1   65.98  ? 102 PRO C CG  1 
ATOM   5427 C  CD  . PRO C 1 106 ? -51.988 30.466  17.665  1   64.35  ? 102 PRO C CD  1 
ATOM   5428 N  N   . LEU C 1 107 ? -49.125 27.825  18.939  1   60.65  ? 103 LEU C N   1 
ATOM   5429 C  CA  . LEU C 1 107 ? -48.083 27.009  19.553  1   55.64  ? 103 LEU C CA  1 
ATOM   5430 C  C   . LEU C 1 107 ? -48.66  26.155  20.69   1   51.81  ? 103 LEU C C   1 
ATOM   5431 O  O   . LEU C 1 107 ? -48.261 25.004  20.869  1   48.62  ? 103 LEU C O   1 
ATOM   5432 C  CB  . LEU C 1 107 ? -46.884 27.856  19.983  1   52.36  ? 103 LEU C CB  1 
ATOM   5433 C  CG  . LEU C 1 107 ? -45.705 27.075  20.563  1   50.68  ? 103 LEU C CG  1 
ATOM   5434 C  CD1 . LEU C 1 107 ? -45.133 26.168  19.497  1   53.42  ? 103 LEU C CD1 1 
ATOM   5435 C  CD2 . LEU C 1 107 ? -44.655 28.029  21.047  1   50.79  ? 103 LEU C CD2 1 
ATOM   5436 N  N   . ILE C 1 108 ? -49.64  26.708  21.42   1   49.57  ? 104 ILE C N   1 
ATOM   5437 C  CA  . ILE C 1 108 ? -50.236 25.986  22.536  1   50.71  ? 104 ILE C CA  1 
ATOM   5438 C  C   . ILE C 1 108 ? -50.936 24.736  22      1   52.72  ? 104 ILE C C   1 
ATOM   5439 O  O   . ILE C 1 108 ? -50.903 23.666  22.616  1   52.65  ? 104 ILE C O   1 
ATOM   5440 C  CB  . ILE C 1 108 ? -51.17  26.876  23.382  1   48.51  ? 104 ILE C CB  1 
ATOM   5441 C  CG1 . ILE C 1 108 ? -50.405 28.022  24.048  1   50.33  ? 104 ILE C CG1 1 
ATOM   5442 C  CG2 . ILE C 1 108 ? -51.912 26.048  24.427  1   46.41  ? 104 ILE C CG2 1 
ATOM   5443 C  CD1 . ILE C 1 108 ? -51.266 29.079  24.731  1   49.5   ? 104 ILE C CD1 1 
ATOM   5444 N  N   . LYS C 1 109 ? -51.55  24.903  20.827  1   56.34  ? 105 LYS C N   1 
ATOM   5445 C  CA  . LYS C 1 109 ? -52.309 23.876  20.138  1   56.53  ? 105 LYS C CA  1 
ATOM   5446 C  C   . LYS C 1 109 ? -51.341 22.795  19.651  1   55.2   ? 105 LYS C C   1 
ATOM   5447 O  O   . LYS C 1 109 ? -51.568 21.606  19.87   1   54.07  ? 105 LYS C O   1 
ATOM   5448 C  CB  . LYS C 1 109 ? -53.076 24.61   19.033  1   61.82  ? 105 LYS C CB  1 
ATOM   5449 C  CG  . LYS C 1 109 ? -54.055 23.808  18.198  1   69.42  ? 105 LYS C CG  1 
ATOM   5450 C  CD  . LYS C 1 109 ? -54.648 24.6    17.031  1   77.54  ? 105 LYS C CD  1 
ATOM   5451 C  CE  . LYS C 1 109 ? -55.685 25.665  17.353  1   78.28  ? 105 LYS C CE  1 
ATOM   5452 N  NZ  . LYS C 1 109 ? -56.834 25.137  18.1    1   76.17  ? 105 LYS C NZ  1 
ATOM   5453 N  N   . SER C 1 110 ? -50.244 23.224  19.016  1   52.24  ? 106 SER C N   1 
ATOM   5454 C  CA  . SER C 1 110 ? -49.243 22.312  18.497  1   49.59  ? 106 SER C CA  1 
ATOM   5455 C  C   . SER C 1 110 ? -48.622 21.516  19.647  1   50.22  ? 106 SER C C   1 
ATOM   5456 O  O   . SER C 1 110 ? -48.246 20.353  19.477  1   52.25  ? 106 SER C O   1 
ATOM   5457 C  CB  . SER C 1 110 ? -48.202 23.071  17.703  1   49.16  ? 106 SER C CB  1 
ATOM   5458 O  OG  . SER C 1 110 ? -47.066 22.263  17.42   1   48.55  ? 106 SER C OG  1 
ATOM   5459 N  N   . TYR C 1 111 ? -48.498 22.145  20.821  1   48.25  ? 107 TYR C N   1 
ATOM   5460 C  CA  . TYR C 1 111 ? -47.85  21.482  21.936  1   45.07  ? 107 TYR C CA  1 
ATOM   5461 C  C   . TYR C 1 111 ? -48.815 20.477  22.553  1   45.52  ? 107 TYR C C   1 
ATOM   5462 O  O   . TYR C 1 111 ? -48.425 19.359  22.865  1   47.17  ? 107 TYR C O   1 
ATOM   5463 C  CB  . TYR C 1 111 ? -47.318 22.499  22.946  1   43.89  ? 107 TYR C CB  1 
ATOM   5464 C  CG  . TYR C 1 111 ? -45.98  23.153  22.622  1   42.68  ? 107 TYR C CG  1 
ATOM   5465 C  CD1 . TYR C 1 111 ? -45.22  22.775  21.511  1   42.16  ? 107 TYR C CD1 1 
ATOM   5466 C  CD2 . TYR C 1 111 ? -45.462 24.137  23.469  1   40.48  ? 107 TYR C CD2 1 
ATOM   5467 C  CE1 . TYR C 1 111 ? -43.984 23.365  21.259  1   43.68  ? 107 TYR C CE1 1 
ATOM   5468 C  CE2 . TYR C 1 111 ? -44.238 24.736  23.22   1   41.28  ? 107 TYR C CE2 1 
ATOM   5469 C  CZ  . TYR C 1 111 ? -43.494 24.349  22.115  1   43.42  ? 107 TYR C CZ  1 
ATOM   5470 O  OH  . TYR C 1 111 ? -42.29  24.961  21.907  1   42.79  ? 107 TYR C OH  1 
ATOM   5471 N  N   . LEU C 1 112 ? -50.081 20.867  22.726  1   47.93  ? 108 LEU C N   1 
ATOM   5472 C  CA  . LEU C 1 112 ? -51.049 19.935  23.278  1   48.52  ? 108 LEU C CA  1 
ATOM   5473 C  C   . LEU C 1 112 ? -51.204 18.724  22.342  1   49.57  ? 108 LEU C C   1 
ATOM   5474 O  O   . LEU C 1 112 ? -51.347 17.587  22.786  1   48.91  ? 108 LEU C O   1 
ATOM   5475 C  CB  . LEU C 1 112 ? -52.372 20.661  23.533  1   49.46  ? 108 LEU C CB  1 
ATOM   5476 C  CG  . LEU C 1 112 ? -53.426 19.812  24.253  1   50.41  ? 108 LEU C CG  1 
ATOM   5477 C  CD1 . LEU C 1 112 ? -52.938 19.533  25.669  1   47.95  ? 108 LEU C CD1 1 
ATOM   5478 C  CD2 . LEU C 1 112 ? -54.798 20.446  24.283  1   50.19  ? 108 LEU C CD2 1 
ATOM   5479 N  N   . PHE C 1 113 ? -51.135 18.969  21.03   1   50.34  ? 109 PHE C N   1 
ATOM   5480 C  CA  . PHE C 1 113 ? -51.417 17.94   20.045  1   52.69  ? 109 PHE C CA  1 
ATOM   5481 C  C   . PHE C 1 113 ? -50.329 16.869  20.092  1   53.46  ? 109 PHE C C   1 
ATOM   5482 O  O   . PHE C 1 113 ? -50.624 15.669  20.062  1   53.25  ? 109 PHE C O   1 
ATOM   5483 C  CB  . PHE C 1 113 ? -51.493 18.602  18.67   1   53.42  ? 109 PHE C CB  1 
ATOM   5484 C  CG  . PHE C 1 113 ? -51.932 17.694  17.534  1   55.28  ? 109 PHE C CG  1 
ATOM   5485 C  CD1 . PHE C 1 113 ? -53.201 17.118  17.544  1   58.7   ? 109 PHE C CD1 1 
ATOM   5486 C  CD2 . PHE C 1 113 ? -51.086 17.44   16.452  1   56.55  ? 109 PHE C CD2 1 
ATOM   5487 C  CE1 . PHE C 1 113 ? -53.623 16.291  16.503  1   59.8   ? 109 PHE C CE1 1 
ATOM   5488 C  CE2 . PHE C 1 113 ? -51.51  16.619  15.412  1   59.36  ? 109 PHE C CE2 1 
ATOM   5489 C  CZ  . PHE C 1 113 ? -52.779 16.055  15.437  1   60.28  ? 109 PHE C CZ  1 
ATOM   5490 N  N   . GLN C 1 114 ? -49.076 17.328  20.144  1   49.62  ? 110 GLN C N   1 
ATOM   5491 C  CA  . GLN C 1 114 ? -47.933 16.436  20.154  1   47.88  ? 110 GLN C CA  1 
ATOM   5492 C  C   . GLN C 1 114 ? -47.848 15.738  21.505  1   46.21  ? 110 GLN C C   1 
ATOM   5493 O  O   . GLN C 1 114 ? -47.403 14.595  21.594  1   46.72  ? 110 GLN C O   1 
ATOM   5494 C  CB  . GLN C 1 114 ? -46.649 17.241  19.967  1   47.55  ? 110 GLN C CB  1 
ATOM   5495 C  CG  . GLN C 1 114 ? -46.577 18.057  18.68   1   45.41  ? 110 GLN C CG  1 
ATOM   5496 C  CD  . GLN C 1 114 ? -45.27  18.809  18.586  1   46.11  ? 110 GLN C CD  1 
ATOM   5497 O  OE1 . GLN C 1 114 ? -44.202 18.195  18.5    1   44.57  ? 110 GLN C OE1 1 
ATOM   5498 N  NE2 . GLN C 1 114 ? -45.329 20.138  18.646  1   46.92  ? 110 GLN C NE2 1 
ATOM   5499 N  N   . LEU C 1 115 ? -48.22  16.462  22.566  1   46.75  ? 111 LEU C N   1 
ATOM   5500 C  CA  . LEU C 1 115 ? -48.177 15.884  23.896  1   43.82  ? 111 LEU C CA  1 
ATOM   5501 C  C   . LEU C 1 115 ? -49.159 14.721  23.94   1   45.78  ? 111 LEU C C   1 
ATOM   5502 O  O   . LEU C 1 115 ? -48.838 13.674  24.483  1   45.91  ? 111 LEU C O   1 
ATOM   5503 C  CB  . LEU C 1 115 ? -48.492 16.928  24.96   1   40.34  ? 111 LEU C CB  1 
ATOM   5504 C  CG  . LEU C 1 115 ? -47.377 17.918  25.313  1   37.02  ? 111 LEU C CG  1 
ATOM   5505 C  CD1 . LEU C 1 115 ? -47.877 18.939  26.334  1   33.71  ? 111 LEU C CD1 1 
ATOM   5506 C  CD2 . LEU C 1 115 ? -46.16  17.212  25.85   1   34.3   ? 111 LEU C CD2 1 
ATOM   5507 N  N   . LEU C 1 116 ? -50.335 14.906  23.324  1   50.44  ? 112 LEU C N   1 
ATOM   5508 C  CA  . LEU C 1 116 ? -51.364 13.879  23.245  1   49.49  ? 112 LEU C CA  1 
ATOM   5509 C  C   . LEU C 1 116 ? -50.901 12.705  22.379  1   51.09  ? 112 LEU C C   1 
ATOM   5510 O  O   . LEU C 1 116 ? -51.258 11.552  22.661  1   51.94  ? 112 LEU C O   1 
ATOM   5511 C  CB  . LEU C 1 116 ? -52.671 14.486  22.743  1   49.35  ? 112 LEU C CB  1 
ATOM   5512 C  CG  . LEU C 1 116 ? -53.462 15.284  23.782  1   53.58  ? 112 LEU C CG  1 
ATOM   5513 C  CD1 . LEU C 1 116 ? -54.525 16.176  23.173  1   55.85  ? 112 LEU C CD1 1 
ATOM   5514 C  CD2 . LEU C 1 116 ? -54.095 14.313  24.77   1   56.18  ? 112 LEU C CD2 1 
ATOM   5515 N  N   . GLN C 1 117 ? -50.128 12.994  21.317  1   48.9   ? 113 GLN C N   1 
ATOM   5516 C  CA  . GLN C 1 117 ? -49.663 11.931  20.435  1   48.92  ? 113 GLN C CA  1 
ATOM   5517 C  C   . GLN C 1 117 ? -48.671 11.071  21.209  1   49.03  ? 113 GLN C C   1 
ATOM   5518 O  O   . GLN C 1 117 ? -48.75  9.843   21.184  1   48.92  ? 113 GLN C O   1 
ATOM   5519 C  CB  . GLN C 1 117 ? -48.995 12.499  19.19   1   48.68  ? 113 GLN C CB  1 
ATOM   5520 C  CG  . GLN C 1 117 ? -49.994 12.93   18.13   1   53.77  ? 113 GLN C CG  1 
ATOM   5521 C  CD  . GLN C 1 117 ? -49.338 13.578  16.932  1   59.98  ? 113 GLN C CD  1 
ATOM   5522 O  OE1 . GLN C 1 117 ? -48.187 14.023  16.968  1   64.28  ? 113 GLN C OE1 1 
ATOM   5523 N  NE2 . GLN C 1 117 ? -50.09  13.663  15.847  1   68.33  ? 113 GLN C NE2 1 
ATOM   5524 N  N   . GLY C 1 118 ? -47.757 11.752  21.918  1   46.72  ? 114 GLY C N   1 
ATOM   5525 C  CA  . GLY C 1 118 ? -46.796 11.112  22.794  1   42.7   ? 114 GLY C CA  1 
ATOM   5526 C  C   . GLY C 1 118 ? -47.508 10.17   23.761  1   45.01  ? 114 GLY C C   1 
ATOM   5527 O  O   . GLY C 1 118 ? -47.159 8.985   23.844  1   49.27  ? 114 GLY C O   1 
ATOM   5528 N  N   . LEU C 1 119 ? -48.521 10.704  24.463  1   43.63  ? 115 LEU C N   1 
ATOM   5529 C  CA  . LEU C 1 119 ? -49.195 9.975   25.523  1   42.89  ? 115 LEU C CA  1 
ATOM   5530 C  C   . LEU C 1 119 ? -50.036 8.83    24.956  1   47.35  ? 115 LEU C C   1 
ATOM   5531 O  O   . LEU C 1 119 ? -50.063 7.749   25.549  1   49.56  ? 115 LEU C O   1 
ATOM   5532 C  CB  . LEU C 1 119 ? -50.003 10.931  26.39   1   41.54  ? 115 LEU C CB  1 
ATOM   5533 C  CG  . LEU C 1 119 ? -50.599 10.318  27.664  1   42.19  ? 115 LEU C CG  1 
ATOM   5534 C  CD1 . LEU C 1 119 ? -49.533 9.845   28.637  1   36.8   ? 115 LEU C CD1 1 
ATOM   5535 C  CD2 . LEU C 1 119 ? -51.546 11.315  28.329  1   41.46  ? 115 LEU C CD2 1 
ATOM   5536 N  N   . ALA C 1 120 ? -50.715 9.057   23.815  1   48.52  ? 116 ALA C N   1 
ATOM   5537 C  CA  . ALA C 1 120 ? -51.475 7.995   23.174  1   49.1   ? 116 ALA C CA  1 
ATOM   5538 C  C   . ALA C 1 120 ? -50.556 6.814   22.874  1   51.83  ? 116 ALA C C   1 
ATOM   5539 O  O   . ALA C 1 120 ? -50.926 5.661   23.131  1   54.21  ? 116 ALA C O   1 
ATOM   5540 C  CB  . ALA C 1 120 ? -52.178 8.469   21.924  1   50.83  ? 116 ALA C CB  1 
ATOM   5541 N  N   . PHE C 1 121 ? -49.355 7.113   22.358  1   48.44  ? 117 PHE C N   1 
ATOM   5542 C  CA  . PHE C 1 121 ? -48.341 6.084   22.162  1   48.71  ? 117 PHE C CA  1 
ATOM   5543 C  C   . PHE C 1 121 ? -48.049 5.34    23.473  1   48.96  ? 117 PHE C C   1 
ATOM   5544 O  O   . PHE C 1 121 ? -48.042 4.098   23.498  1   49.59  ? 117 PHE C O   1 
ATOM   5545 C  CB  . PHE C 1 121 ? -47.023 6.66    21.631  1   45.98  ? 117 PHE C CB  1 
ATOM   5546 C  CG  . PHE C 1 121 ? -46.178 5.605   20.921  1   45.24  ? 117 PHE C CG  1 
ATOM   5547 C  CD1 . PHE C 1 121 ? -46.458 5.241   19.595  1   45.53  ? 117 PHE C CD1 1 
ATOM   5548 C  CD2 . PHE C 1 121 ? -45.103 4.983   21.561  1   40.31  ? 117 PHE C CD2 1 
ATOM   5549 C  CE1 . PHE C 1 121 ? -45.707 4.274   18.931  1   42.94  ? 117 PHE C CE1 1 
ATOM   5550 C  CE2 . PHE C 1 121 ? -44.364 4.008   20.892  1   40.91  ? 117 PHE C CE2 1 
ATOM   5551 C  CZ  . PHE C 1 121 ? -44.669 3.655   19.582  1   41.3   ? 117 PHE C CZ  1 
ATOM   5552 N  N   . CYS C 1 122 ? -47.762 6.103   24.544  1   43.62  ? 118 CYS C N   1 
ATOM   5553 C  CA  . CYS C 1 122 ? -47.495 5.498   25.843  1   43.05  ? 118 CYS C CA  1 
ATOM   5554 C  C   . CYS C 1 122 ? -48.632 4.585   26.267  1   45.6   ? 118 CYS C C   1 
ATOM   5555 O  O   . CYS C 1 122 ? -48.374 3.438   26.632  1   49.42  ? 118 CYS C O   1 
ATOM   5556 C  CB  . CYS C 1 122 ? -47.309 6.512   26.956  1   39.33  ? 118 CYS C CB  1 
ATOM   5557 S  SG  . CYS C 1 122 ? -45.719 7.332   26.772  1   41.62  ? 118 CYS C SG  1 
ATOM   5558 N  N   . HIS C 1 123 ? -49.867 5.108   26.191  1   47.55  ? 119 HIS C N   1 
ATOM   5559 C  CA  . HIS C 1 123 ? -51.041 4.384   26.64   1   48.07  ? 119 HIS C CA  1 
ATOM   5560 C  C   . HIS C 1 123 ? -51.26  3.142   25.781  1   49.53  ? 119 HIS C C   1 
ATOM   5561 O  O   . HIS C 1 123 ? -51.701 2.115   26.289  1   49.83  ? 119 HIS C O   1 
ATOM   5562 C  CB  . HIS C 1 123 ? -52.234 5.325   26.794  1   49.14  ? 119 HIS C CB  1 
ATOM   5563 C  CG  . HIS C 1 123 ? -52.065 6.242   27.955  1   49.59  ? 119 HIS C CG  1 
ATOM   5564 N  ND1 . HIS C 1 123 ? -52.94  7.272   28.211  1   50.29  ? 119 HIS C ND1 1 
ATOM   5565 C  CD2 . HIS C 1 123 ? -51.149 6.272   28.946  1   49.02  ? 119 HIS C CD2 1 
ATOM   5566 C  CE1 . HIS C 1 123 ? -52.553 7.904   29.315  1   50.01  ? 119 HIS C CE1 1 
ATOM   5567 N  NE2 . HIS C 1 123 ? -51.469 7.313   29.781  1   48.53  ? 119 HIS C NE2 1 
ATOM   5568 N  N   . SER C 1 124 ? -50.906 3.236   24.499  1   47.09  ? 120 SER C N   1 
ATOM   5569 C  CA  . SER C 1 124 ? -51.173 2.134   23.603  1   50.07  ? 120 SER C CA  1 
ATOM   5570 C  C   . SER C 1 124 ? -50.054 1.093   23.706  1   49.87  ? 120 SER C C   1 
ATOM   5571 O  O   . SER C 1 124 ? -50.154 0.041   23.06   1   48.73  ? 120 SER C O   1 
ATOM   5572 C  CB  . SER C 1 124 ? -51.439 2.604   22.169  1   53.03  ? 120 SER C CB  1 
ATOM   5573 O  OG  . SER C 1 124 ? -50.246 3.025   21.523  1   59.21  ? 120 SER C OG  1 
ATOM   5574 N  N   . HIS C 1 125 ? -49.031 1.395   24.509  1   45.97  ? 121 HIS C N   1 
ATOM   5575 C  CA  . HIS C 1 125 ? -47.93  0.424   24.742  1   47.24  ? 121 HIS C CA  1 
ATOM   5576 C  C   . HIS C 1 125 ? -47.934 0.098   26.235  1   47.04  ? 121 HIS C C   1 
ATOM   5577 O  O   . HIS C 1 125 ? -46.844 0.004   26.828  1   47.71  ? 121 HIS C O   1 
ATOM   5578 C  CB  . HIS C 1 125 ? -46.601 0.991   24.234  1   49.2   ? 121 HIS C CB  1 
ATOM   5579 C  CG  . HIS C 1 125 ? -46.538 1.044   22.746  1   56.48  ? 121 HIS C CG  1 
ATOM   5580 N  ND1 . HIS C 1 125 ? -47.409 1.798   21.99   1   57.27  ? 121 HIS C ND1 1 
ATOM   5581 C  CD2 . HIS C 1 125 ? -45.729 0.431   21.876  1   58.4   ? 121 HIS C CD2 1 
ATOM   5582 C  CE1 . HIS C 1 125 ? -47.128 1.636   20.708  1   57.84  ? 121 HIS C CE1 1 
ATOM   5583 N  NE2 . HIS C 1 125 ? -46.108 0.811   20.615  1   59.28  ? 121 HIS C NE2 1 
ATOM   5584 N  N   . ARG C 1 126 ? -49.108 -0.033  26.835  1   49.13  ? 122 ARG C N   1 
ATOM   5585 C  CA  . ARG C 1 126 ? -49.253 -0.369  28.278  1   48.97  ? 122 ARG C CA  1 
ATOM   5586 C  C   . ARG C 1 126 ? -48.235 0.386   29.161  1   43.21  ? 122 ARG C C   1 
ATOM   5587 O  O   . ARG C 1 126 ? -47.625 -0.256  30.015  1   41.59  ? 122 ARG C O   1 
ATOM   5588 C  CB  . ARG C 1 126 ? -49.21  -1.884  28.54   1   50.11  ? 122 ARG C CB  1 
ATOM   5589 C  CG  . ARG C 1 126 ? -48.257 -2.788  27.772  1   54.21  ? 122 ARG C CG  1 
ATOM   5590 C  CD  . ARG C 1 126 ? -47.233 -3.431  28.689  1   56.02  ? 122 ARG C CD  1 
ATOM   5591 N  NE  . ARG C 1 126 ? -45.956 -2.712  28.665  1   56.08  ? 122 ARG C NE  1 
ATOM   5592 C  CZ  . ARG C 1 126 ? -45.04  -2.817  27.714  1   52.94  ? 122 ARG C CZ  1 
ATOM   5593 N  NH1 . ARG C 1 126 ? -44.552 -3.999  27.389  1   46.5   ? 122 ARG C NH1 1 
ATOM   5594 N  NH2 . ARG C 1 126 ? -44.608 -1.737  27.096  1   51.69  ? 122 ARG C NH2 1 
ATOM   5595 N  N   . VAL C 1 127 ? -48.147 1.709   29.025  1   41.05  ? 123 VAL C N   1 
ATOM   5596 C  CA  . VAL C 1 127 ? -47.188 2.464   29.829  1   37.16  ? 123 VAL C CA  1 
ATOM   5597 C  C   . VAL C 1 127 ? -47.871 3.715   30.409  1   36.38  ? 123 VAL C C   1 
ATOM   5598 O  O   . VAL C 1 127 ? -48.306 4.596   29.666  1   36.49  ? 123 VAL C O   1 
ATOM   5599 C  CB  . VAL C 1 127 ? -45.881 2.829   29.076  1   35.37  ? 123 VAL C CB  1 
ATOM   5600 C  CG1 . VAL C 1 127 ? -45.056 3.903   29.799  1   32.01  ? 123 VAL C CG1 1 
ATOM   5601 C  CG2 . VAL C 1 127 ? -44.97  1.654   28.772  1   32.98  ? 123 VAL C CG2 1 
ATOM   5602 N  N   . LEU C 1 128 ? -47.967 3.792   31.744  1   35.92  ? 124 LEU C N   1 
ATOM   5603 C  CA  . LEU C 1 128 ? -48.387 5.018   32.409  1   36.6   ? 124 LEU C CA  1 
ATOM   5604 C  C   . LEU C 1 128 ? -47.157 5.894   32.63   1   35.99  ? 124 LEU C C   1 
ATOM   5605 O  O   . LEU C 1 128 ? -46.133 5.364   33.056  1   37.38  ? 124 LEU C O   1 
ATOM   5606 C  CB  . LEU C 1 128 ? -49.014 4.696   33.759  1   36.13  ? 124 LEU C CB  1 
ATOM   5607 C  CG  . LEU C 1 128 ? -50.318 3.917   33.738  1   39.36  ? 124 LEU C CG  1 
ATOM   5608 C  CD1 . LEU C 1 128 ? -50.795 3.808   35.194  1   38.65  ? 124 LEU C CD1 1 
ATOM   5609 C  CD2 . LEU C 1 128 ? -51.295 4.621   32.806  1   40.25  ? 124 LEU C CD2 1 
ATOM   5610 N  N   . HIS C 1 129 ? -47.267 7.216   32.404  1   36     ? 125 HIS C N   1 
ATOM   5611 C  CA  . HIS C 1 129 ? -46.14  8.112   32.645  1   37.02  ? 125 HIS C CA  1 
ATOM   5612 C  C   . HIS C 1 129 ? -46.099 8.518   34.117  1   39.95  ? 125 HIS C C   1 
ATOM   5613 O  O   . HIS C 1 129 ? -45.071 8.34    34.783  1   37.44  ? 125 HIS C O   1 
ATOM   5614 C  CB  . HIS C 1 129 ? -46.163 9.345   31.732  1   37.69  ? 125 HIS C CB  1 
ATOM   5615 C  CG  . HIS C 1 129 ? -44.963 10.23   31.904  1   38.31  ? 125 HIS C CG  1 
ATOM   5616 N  ND1 . HIS C 1 129 ? -44.766 11.047  33.01   1   36.05  ? 125 HIS C ND1 1 
ATOM   5617 C  CD2 . HIS C 1 129 ? -43.897 10.419  31.107  1   36.72  ? 125 HIS C CD2 1 
ATOM   5618 C  CE1 . HIS C 1 129 ? -43.611 11.688  32.88   1   36.14  ? 125 HIS C CE1 1 
ATOM   5619 N  NE2 . HIS C 1 129 ? -43.067 11.332  31.733  1   36.75  ? 125 HIS C NE2 1 
ATOM   5620 N  N   . ARG C 1 130 ? -47.205 9.105   34.608  1   38.72  ? 126 ARG C N   1 
ATOM   5621 C  CA  . ARG C 1 130 ? -47.411 9.231   36.05   1   38.79  ? 126 ARG C CA  1 
ATOM   5622 C  C   . ARG C 1 130 ? -46.615 10.388  36.642  1   36.85  ? 126 ARG C C   1 
ATOM   5623 O  O   . ARG C 1 130 ? -46.589 10.574  37.856  1   39.99  ? 126 ARG C O   1 
ATOM   5624 C  CB  . ARG C 1 130 ? -47.15  7.956   36.87   1   37.8   ? 126 ARG C CB  1 
ATOM   5625 C  CG  . ARG C 1 130 ? -48.062 6.785   36.505  1   38.35  ? 126 ARG C CG  1 
ATOM   5626 C  CD  . ARG C 1 130 ? -48.196 5.8     37.666  1   38.58  ? 126 ARG C CD  1 
ATOM   5627 N  NE  . ARG C 1 130 ? -46.872 5.302   38.061  1   39.13  ? 126 ARG C NE  1 
ATOM   5628 C  CZ  . ARG C 1 130 ? -46.564 4.28    38.848  1   41.24  ? 126 ARG C CZ  1 
ATOM   5629 N  NH1 . ARG C 1 130 ? -47.504 3.602   39.491  1   41.81  ? 126 ARG C NH1 1 
ATOM   5630 N  NH2 . ARG C 1 130 ? -45.291 3.927   38.962  1   39.96  ? 126 ARG C NH2 1 
ATOM   5631 N  N   . ASP C 1 131 ? -46.004 11.197  35.786  1   35.31  ? 127 ASP C N   1 
ATOM   5632 C  CA  . ASP C 1 131 ? -45.327 12.365  36.313  1   36.04  ? 127 ASP C CA  1 
ATOM   5633 C  C   . ASP C 1 131 ? -45.265 13.455  35.255  1   36.06  ? 127 ASP C C   1 
ATOM   5634 O  O   . ASP C 1 131 ? -44.213 14.082  35.061  1   33.66  ? 127 ASP C O   1 
ATOM   5635 C  CB  . ASP C 1 131 ? -43.937 12.068  36.851  1   36.12  ? 127 ASP C CB  1 
ATOM   5636 C  CG  . ASP C 1 131 ? -43.384 13.154  37.761  1   37.97  ? 127 ASP C CG  1 
ATOM   5637 O  OD1 . ASP C 1 131 ? -44.185 13.999  38.26   1   37.92  ? 127 ASP C OD1 1 
ATOM   5638 O  OD2 . ASP C 1 131 ? -42.156 13.172  37.948  1   40.98  ? 127 ASP C OD2 1 
ATOM   5639 N  N   . LEU C 1 132 ? -46.402 13.686  34.599  1   33.98  ? 128 LEU C N   1 
ATOM   5640 C  CA  . LEU C 1 132 ? -46.395 14.745  33.611  1   37.35  ? 128 LEU C CA  1 
ATOM   5641 C  C   . LEU C 1 132 ? -46.562 16.09   34.325  1   38.55  ? 128 LEU C C   1 
ATOM   5642 O  O   . LEU C 1 132 ? -47.465 16.282  35.121  1   43.92  ? 128 LEU C O   1 
ATOM   5643 C  CB  . LEU C 1 132 ? -47.443 14.464  32.536  1   39.61  ? 128 LEU C CB  1 
ATOM   5644 C  CG  . LEU C 1 132 ? -47.273 13.124  31.81   1   37.52  ? 128 LEU C CG  1 
ATOM   5645 C  CD1 . LEU C 1 132 ? -48.613 12.574  31.315  1   38.91  ? 128 LEU C CD1 1 
ATOM   5646 C  CD2 . LEU C 1 132 ? -46.24  13.199  30.688  1   36.44  ? 128 LEU C CD2 1 
ATOM   5647 N  N   . LYS C 1 133 ? -45.591 16.974  34.137  1   36.13  ? 129 LYS C N   1 
ATOM   5648 C  CA  . LYS C 1 133 ? -45.659 18.342  34.59   1   35.39  ? 129 LYS C CA  1 
ATOM   5649 C  C   . LYS C 1 133 ? -44.769 19.122  33.633  1   36.9   ? 129 LYS C C   1 
ATOM   5650 O  O   . LYS C 1 133 ? -44.021 18.517  32.869  1   39.12  ? 129 LYS C O   1 
ATOM   5651 C  CB  . LYS C 1 133 ? -45.233 18.405  36.055  1   32.75  ? 129 LYS C CB  1 
ATOM   5652 C  CG  . LYS C 1 133 ? -43.89  17.768  36.305  1   34.63  ? 129 LYS C CG  1 
ATOM   5653 C  CD  . LYS C 1 133 ? -43.381 17.931  37.731  1   34.97  ? 129 LYS C CD  1 
ATOM   5654 C  CE  . LYS C 1 133 ? -42.191 17.075  37.924  1   34.14  ? 129 LYS C CE  1 
ATOM   5655 N  NZ  . LYS C 1 133 ? -41.491 17.639  39.067  1   36.06  ? 129 LYS C NZ  1 
ATOM   5656 N  N   . PRO C 1 134 ? -44.828 20.47   33.594  1   36.47  ? 130 PRO C N   1 
ATOM   5657 C  CA  . PRO C 1 134 ? -44.105 21.191  32.553  1   36.04  ? 130 PRO C CA  1 
ATOM   5658 C  C   . PRO C 1 134 ? -42.601 20.924  32.591  1   37.09  ? 130 PRO C C   1 
ATOM   5659 O  O   . PRO C 1 134 ? -41.968 20.938  31.534  1   37.87  ? 130 PRO C O   1 
ATOM   5660 C  CB  . PRO C 1 134 ? -44.479 22.637  32.784  1   36.91  ? 130 PRO C CB  1 
ATOM   5661 C  CG  . PRO C 1 134 ? -45.727 22.566  33.629  1   37.16  ? 130 PRO C CG  1 
ATOM   5662 C  CD  . PRO C 1 134 ? -45.586 21.343  34.501  1   35.75  ? 130 PRO C CD  1 
ATOM   5663 N  N   . GLN C 1 135 ? -42.067 20.611  33.794  1   36.07  ? 131 GLN C N   1 
ATOM   5664 C  CA  . GLN C 1 135 ? -40.638 20.418  34.043  1   34.24  ? 131 GLN C CA  1 
ATOM   5665 C  C   . GLN C 1 135 ? -40.147 19.133  33.369  1   35.16  ? 131 GLN C C   1 
ATOM   5666 O  O   . GLN C 1 135 ? -38.93  18.913  33.271  1   35.89  ? 131 GLN C O   1 
ATOM   5667 C  CB  . GLN C 1 135 ? -40.29  20.273  35.533  1   35.09  ? 131 GLN C CB  1 
ATOM   5668 C  CG  . GLN C 1 135 ? -40.584 21.499  36.404  1   38.38  ? 131 GLN C CG  1 
ATOM   5669 C  CD  . GLN C 1 135 ? -42.056 21.758  36.695  1   39.71  ? 131 GLN C CD  1 
ATOM   5670 O  OE1 . GLN C 1 135 ? -42.962 21.038  36.256  1   39.86  ? 131 GLN C OE1 1 
ATOM   5671 N  NE2 . GLN C 1 135 ? -42.332 22.836  37.415  1   43.09  ? 131 GLN C NE2 1 
ATOM   5672 N  N   . ASN C 1 136 ? -41.092 18.275  32.94   1   30.24  ? 132 ASN C N   1 
ATOM   5673 C  CA  . ASN C 1 136 ? -40.732 16.995  32.368  1   30.07  ? 132 ASN C CA  1 
ATOM   5674 C  C   . ASN C 1 136 ? -41.116 16.942  30.9    1   31.29  ? 132 ASN C C   1 
ATOM   5675 O  O   . ASN C 1 136 ? -41.176 15.866  30.341  1   31.4   ? 132 ASN C O   1 
ATOM   5676 C  CB  . ASN C 1 136 ? -41.403 15.836  33.093  1   29.44  ? 132 ASN C CB  1 
ATOM   5677 C  CG  . ASN C 1 136 ? -40.852 15.651  34.486  1   29.67  ? 132 ASN C CG  1 
ATOM   5678 O  OD1 . ASN C 1 136 ? -39.84  16.271  34.831  1   29.02  ? 132 ASN C OD1 1 
ATOM   5679 N  ND2 . ASN C 1 136 ? -41.477 14.792  35.286  1   29.44  ? 132 ASN C ND2 1 
ATOM   5680 N  N   . LEU C 1 137 ? -41.389 18.096  30.285  1   33.35  ? 133 LEU C N   1 
ATOM   5681 C  CA  . LEU C 1 137 ? -41.684 18.151  28.862  1   31.82  ? 133 LEU C CA  1 
ATOM   5682 C  C   . LEU C 1 137 ? -40.626 19.029  28.214  1   33.63  ? 133 LEU C C   1 
ATOM   5683 O  O   . LEU C 1 137 ? -40.367 20.139  28.684  1   34.75  ? 133 LEU C O   1 
ATOM   5684 C  CB  . LEU C 1 137 ? -43.074 18.768  28.76   1   32.72  ? 133 LEU C CB  1 
ATOM   5685 C  CG  . LEU C 1 137 ? -44.174 18.037  29.537  1   33.61  ? 133 LEU C CG  1 
ATOM   5686 C  CD1 . LEU C 1 137 ? -45.518 18.742  29.373  1   32.8   ? 133 LEU C CD1 1 
ATOM   5687 C  CD2 . LEU C 1 137 ? -44.275 16.576  29.054  1   32.17  ? 133 LEU C CD2 1 
ATOM   5688 N  N   . LEU C 1 138 ? -39.969 18.504  27.176  1   34.68  ? 134 LEU C N   1 
ATOM   5689 C  CA  . LEU C 1 138 ? -38.823 19.179  26.576  1   34.91  ? 134 LEU C CA  1 
ATOM   5690 C  C   . LEU C 1 138 ? -39.187 19.695  25.19   1   38.73  ? 134 LEU C C   1 
ATOM   5691 O  O   . LEU C 1 138 ? -39.834 18.991  24.383  1   37.43  ? 134 LEU C O   1 
ATOM   5692 C  CB  . LEU C 1 138 ? -37.626 18.233  26.509  1   33.68  ? 134 LEU C CB  1 
ATOM   5693 C  CG  . LEU C 1 138 ? -37.221 17.612  27.853  1   32.83  ? 134 LEU C CG  1 
ATOM   5694 C  CD1 . LEU C 1 138 ? -36.247 16.475  27.641  1   32.51  ? 134 LEU C CD1 1 
ATOM   5695 C  CD2 . LEU C 1 138 ? -36.714 18.597  28.915  1   30.68  ? 134 LEU C CD2 1 
ATOM   5696 N  N   . ILE C 1 139 ? -38.731 20.928  24.918  1   38.27  ? 135 ILE C N   1 
ATOM   5697 C  CA  . ILE C 1 139 ? -39.011 21.519  23.618  1   38.99  ? 135 ILE C CA  1 
ATOM   5698 C  C   . ILE C 1 139 ? -37.693 21.728  22.885  1   40.62  ? 135 ILE C C   1 
ATOM   5699 O  O   . ILE C 1 139 ? -36.678 22.01   23.508  1   39.83  ? 135 ILE C O   1 
ATOM   5700 C  CB  . ILE C 1 139 ? -39.783 22.844  23.759  1   37.37  ? 135 ILE C CB  1 
ATOM   5701 C  CG1 . ILE C 1 139 ? -38.996 23.879  24.499  1   36.49  ? 135 ILE C CG1 1 
ATOM   5702 C  CG2 . ILE C 1 139 ? -41.168 22.646  24.373  1   35.64  ? 135 ILE C CG2 1 
ATOM   5703 C  CD1 . ILE C 1 139 ? -39.677 25.233  24.454  1   39.33  ? 135 ILE C CD1 1 
ATOM   5704 N  N   . ASN C 1 140 ? -37.731 21.638  21.556  1   45.28  ? 136 ASN C N   1 
ATOM   5705 C  CA  . ASN C 1 140 ? -36.585 22.075  20.765  1   53.65  ? 136 ASN C CA  1 
ATOM   5706 C  C   . ASN C 1 140 ? -36.854 23.468  20.19   1   60.04  ? 136 ASN C C   1 
ATOM   5707 O  O   . ASN C 1 140 ? -37.863 24.099  20.53   1   60.23  ? 136 ASN C O   1 
ATOM   5708 C  CB  . ASN C 1 140 ? -36.16  21.033  19.734  1   50.96  ? 136 ASN C CB  1 
ATOM   5709 C  CG  . ASN C 1 140 ? -37.233 20.759  18.709  1   51.26  ? 136 ASN C CG  1 
ATOM   5710 O  OD1 . ASN C 1 140 ? -38.11  21.599  18.45   1   52.24  ? 136 ASN C OD1 1 
ATOM   5711 N  ND2 . ASN C 1 140 ? -37.195 19.571  18.131  1   50.05  ? 136 ASN C ND2 1 
ATOM   5712 N  N   . THR C 1 141 ? -35.934 23.93   19.324  1   65.55  ? 137 THR C N   1 
ATOM   5713 C  CA  . THR C 1 141 ? -36     25.269  18.744  1   68.51  ? 137 THR C CA  1 
ATOM   5714 C  C   . THR C 1 141 ? -36.913 25.258  17.522  1   73.09  ? 137 THR C C   1 
ATOM   5715 O  O   . THR C 1 141 ? -37.223 26.326  16.988  1   82.27  ? 137 THR C O   1 
ATOM   5716 C  CB  . THR C 1 141 ? -34.624 25.805  18.353  1   65.8   ? 137 THR C CB  1 
ATOM   5717 O  OG1 . THR C 1 141 ? -34.185 24.92   17.326  1   69.22  ? 137 THR C OG1 1 
ATOM   5718 C  CG2 . THR C 1 141 ? -33.652 25.86   19.516  1   64.52  ? 137 THR C CG2 1 
ATOM   5719 N  N   . GLU C 1 142 ? -37.338 24.051  17.116  1   68.62  ? 138 GLU C N   1 
ATOM   5720 C  CA  . GLU C 1 142 ? -38.011 23.832  15.845  1   67.45  ? 138 GLU C CA  1 
ATOM   5721 C  C   . GLU C 1 142 ? -39.455 23.362  16.044  1   64.23  ? 138 GLU C C   1 
ATOM   5722 O  O   . GLU C 1 142 ? -40.047 22.804  15.118  1   65.23  ? 138 GLU C O   1 
ATOM   5723 C  CB  . GLU C 1 142 ? -37.211 22.83   15.013  1   70.86  ? 138 GLU C CB  1 
ATOM   5724 C  CG  . GLU C 1 142 ? -35.71  23.101  15.038  1   79.82  ? 138 GLU C CG  1 
ATOM   5725 C  CD  . GLU C 1 142 ? -34.963 22.527  13.85   1   89.07  ? 138 GLU C CD  1 
ATOM   5726 O  OE1 . GLU C 1 142 ? -35.043 21.297  13.639  1   94.56  ? 138 GLU C OE1 1 
ATOM   5727 O  OE2 . GLU C 1 142 ? -34.3   23.313  13.132  1   93.05  ? 138 GLU C OE2 1 
ATOM   5728 N  N   . GLY C 1 143 ? -40.019 23.567  17.243  1   56.1   ? 139 GLY C N   1 
ATOM   5729 C  CA  . GLY C 1 143 ? -41.462 23.444  17.415  1   53.35  ? 139 GLY C CA  1 
ATOM   5730 C  C   . GLY C 1 143 ? -41.912 22.094  17.988  1   52.49  ? 139 GLY C C   1 
ATOM   5731 O  O   . GLY C 1 143 ? -43.124 21.854  18.13   1   50.51  ? 139 GLY C O   1 
ATOM   5732 N  N   . ALA C 1 144 ? -40.949 21.207  18.312  1   47.39  ? 140 ALA C N   1 
ATOM   5733 C  CA  . ALA C 1 144 ? -41.314 19.921  18.894  1   44.01  ? 140 ALA C CA  1 
ATOM   5734 C  C   . ALA C 1 144 ? -41.333 20.028  20.414  1   44.55  ? 140 ALA C C   1 
ATOM   5735 O  O   . ALA C 1 144 ? -40.574 20.818  21.014  1   42.81  ? 140 ALA C O   1 
ATOM   5736 C  CB  . ALA C 1 144 ? -40.364 18.848  18.46   1   41.69  ? 140 ALA C CB  1 
ATOM   5737 N  N   . ILE C 1 145 ? -42.238 19.23   21      1   42.38  ? 141 ILE C N   1 
ATOM   5738 C  CA  . ILE C 1 145 ? -42.252 18.975  22.43   1   41.6   ? 141 ILE C CA  1 
ATOM   5739 C  C   . ILE C 1 145 ? -42.25  17.469  22.637  1   42.51  ? 141 ILE C C   1 
ATOM   5740 O  O   . ILE C 1 145 ? -42.793 16.739  21.806  1   48.43  ? 141 ILE C O   1 
ATOM   5741 C  CB  . ILE C 1 145 ? -43.47  19.646  23.081  1   41.72  ? 141 ILE C CB  1 
ATOM   5742 C  CG1 . ILE C 1 145 ? -43.33  19.695  24.616  1   39.69  ? 141 ILE C CG1 1 
ATOM   5743 C  CG2 . ILE C 1 145 ? -44.778 19.005  22.601  1   41.93  ? 141 ILE C CG2 1 
ATOM   5744 C  CD1 . ILE C 1 145 ? -44.244 20.704  25.291  1   39.59  ? 141 ILE C CD1 1 
ATOM   5745 N  N   . LYS C 1 146 ? -41.614 17      23.72   1   41.53  ? 142 LYS C N   1 
ATOM   5746 C  CA  . LYS C 1 146 ? -41.519 15.561  23.956  1   40.64  ? 142 LYS C CA  1 
ATOM   5747 C  C   . LYS C 1 146 ? -41.761 15.235  25.426  1   40.46  ? 142 LYS C C   1 
ATOM   5748 O  O   . LYS C 1 146 ? -41.416 16.035  26.294  1   41.32  ? 142 LYS C O   1 
ATOM   5749 C  CB  . LYS C 1 146 ? -40.154 15.015  23.525  1   40.39  ? 142 LYS C CB  1 
ATOM   5750 C  CG  . LYS C 1 146 ? -39.817 15.256  22.062  1   42.93  ? 142 LYS C CG  1 
ATOM   5751 C  CD  . LYS C 1 146 ? -38.495 14.648  21.6    1   43.57  ? 142 LYS C CD  1 
ATOM   5752 C  CE  . LYS C 1 146 ? -38.192 15.016  20.165  1   43.43  ? 142 LYS C CE  1 
ATOM   5753 N  NZ  . LYS C 1 146 ? -37.25  14.097  19.531  1   41.36  ? 142 LYS C NZ  1 
ATOM   5754 N  N   . LEU C 1 147 ? -42.341 14.052  25.691  1   40.01  ? 143 LEU C N   1 
ATOM   5755 C  CA  . LEU C 1 147 ? -42.448 13.532  27.048  1   36.77  ? 143 LEU C CA  1 
ATOM   5756 C  C   . LEU C 1 147 ? -41.053 13.091  27.468  1   38.33  ? 143 LEU C C   1 
ATOM   5757 O  O   . LEU C 1 147 ? -40.348 12.393  26.716  1   40.53  ? 143 LEU C O   1 
ATOM   5758 C  CB  . LEU C 1 147 ? -43.405 12.356  27.286  1   36.79  ? 143 LEU C CB  1 
ATOM   5759 C  CG  . LEU C 1 147 ? -44.722 12.286  26.509  1   38.72  ? 143 LEU C CG  1 
ATOM   5760 C  CD1 . LEU C 1 147 ? -45.658 11.204  27.07   1   36.55  ? 143 LEU C CD1 1 
ATOM   5761 C  CD2 . LEU C 1 147 ? -45.369 13.65   26.497  1   37.08  ? 143 LEU C CD2 1 
ATOM   5762 N  N   . ALA C 1 148 ? -40.691 13.473  28.688  1   34     ? 144 ALA C N   1 
ATOM   5763 C  CA  . ALA C 1 148 ? -39.434 13.014  29.246  1   36.7   ? 144 ALA C CA  1 
ATOM   5764 C  C   . ALA C 1 148 ? -39.607 12.673  30.725  1   37.5   ? 144 ALA C C   1 
ATOM   5765 O  O   . ALA C 1 148 ? -40.711 12.703  31.263  1   38.77  ? 144 ALA C O   1 
ATOM   5766 C  CB  . ALA C 1 148 ? -38.356 14.046  29.016  1   35.43  ? 144 ALA C CB  1 
ATOM   5767 N  N   . ASP C 1 149 ? -38.496 12.277  31.343  1   37.22  ? 145 ASP C N   1 
ATOM   5768 C  CA  . ASP C 1 149 ? -38.431 11.767  32.694  1   36.56  ? 145 ASP C CA  1 
ATOM   5769 C  C   . ASP C 1 149 ? -39.446 10.649  32.946  1   38.26  ? 145 ASP C C   1 
ATOM   5770 O  O   . ASP C 1 149 ? -40.492 10.885  33.558  1   39.88  ? 145 ASP C O   1 
ATOM   5771 C  CB  . ASP C 1 149 ? -38.527 12.91   33.679  1   38.28  ? 145 ASP C CB  1 
ATOM   5772 C  CG  . ASP C 1 149 ? -38.059 12.47   35.048  1   45.79  ? 145 ASP C CG  1 
ATOM   5773 O  OD1 . ASP C 1 149 ? -37.933 11.225  35.212  1   44.9   ? 145 ASP C OD1 1 
ATOM   5774 O  OD2 . ASP C 1 149 ? -37.758 13.363  35.89   1   48.36  ? 145 ASP C OD2 1 
ATOM   5775 N  N   . PHE C 1 150 ? -39.121 9.42    32.512  1   37.33  ? 146 PHE C N   1 
ATOM   5776 C  CA  . PHE C 1 150 ? -39.948 8.243   32.774  1   34.76  ? 146 PHE C CA  1 
ATOM   5777 C  C   . PHE C 1 150 ? -39.533 7.52    34.063  1   36.42  ? 146 PHE C C   1 
ATOM   5778 O  O   . PHE C 1 150 ? -39.773 6.319   34.237  1   35.75  ? 146 PHE C O   1 
ATOM   5779 C  CB  . PHE C 1 150 ? -39.867 7.328   31.563  1   32.63  ? 146 PHE C CB  1 
ATOM   5780 C  CG  . PHE C 1 150 ? -40.694 7.831   30.401  1   35.48  ? 146 PHE C CG  1 
ATOM   5781 C  CD1 . PHE C 1 150 ? -40.348 9.005   29.734  1   36.58  ? 146 PHE C CD1 1 
ATOM   5782 C  CD2 . PHE C 1 150 ? -41.793 7.096   29.944  1   35.84  ? 146 PHE C CD2 1 
ATOM   5783 C  CE1 . PHE C 1 150 ? -41.111 9.446   28.645  1   39.57  ? 146 PHE C CE1 1 
ATOM   5784 C  CE2 . PHE C 1 150 ? -42.531 7.522   28.838  1   36.32  ? 146 PHE C CE2 1 
ATOM   5785 C  CZ  . PHE C 1 150 ? -42.197 8.696   28.188  1   36.35  ? 146 PHE C CZ  1 
ATOM   5786 N  N   . GLY C 1 151 ? -38.953 8.281   34.999  1   36.04  ? 147 GLY C N   1 
ATOM   5787 C  CA  . GLY C 1 151 ? -38.537 7.769   36.289  1   37.89  ? 147 GLY C CA  1 
ATOM   5788 C  C   . GLY C 1 151 ? -39.692 7.196   37.118  1   39.49  ? 147 GLY C C   1 
ATOM   5789 O  O   . GLY C 1 151 ? -39.47  6.292   37.929  1   41.95  ? 147 GLY C O   1 
ATOM   5790 N  N   . LEU C 1 152 ? -40.906 7.73    36.924  1   38.2   ? 148 LEU C N   1 
ATOM   5791 C  CA  . LEU C 1 152 ? -42.062 7.281   37.687  1   39.63  ? 148 LEU C CA  1 
ATOM   5792 C  C   . LEU C 1 152 ? -43.015 6.464   36.811  1   37.52  ? 148 LEU C C   1 
ATOM   5793 O  O   . LEU C 1 152 ? -44.16  6.221   37.181  1   42.22  ? 148 LEU C O   1 
ATOM   5794 C  CB  . LEU C 1 152 ? -42.767 8.478   38.317  1   43.47  ? 148 LEU C CB  1 
ATOM   5795 C  CG  . LEU C 1 152 ? -42.177 9.039   39.615  1   48.51  ? 148 LEU C CG  1 
ATOM   5796 C  CD1 . LEU C 1 152 ? -43.119 10.162  40.075  1   47.31  ? 148 LEU C CD1 1 
ATOM   5797 C  CD2 . LEU C 1 152 ? -42.072 7.948   40.69   1   45.75  ? 148 LEU C CD2 1 
ATOM   5798 N  N   . ALA C 1 153 ? -42.528 5.995   35.668  1   33.67  ? 149 ALA C N   1 
ATOM   5799 C  CA  . ALA C 1 153 ? -43.389 5.328   34.71   1   35     ? 149 ALA C CA  1 
ATOM   5800 C  C   . ALA C 1 153 ? -43.578 3.865   35.083  1   39.22  ? 149 ALA C C   1 
ATOM   5801 O  O   . ALA C 1 153 ? -42.732 3.261   35.744  1   43.2   ? 149 ALA C O   1 
ATOM   5802 C  CB  . ALA C 1 153 ? -42.816 5.481   33.321  1   33.6   ? 149 ALA C CB  1 
ATOM   5803 N  N   . ARG C 1 154 ? -44.673 3.268   34.601  1   39.84  ? 150 ARG C N   1 
ATOM   5804 C  CA  . ARG C 1 154 ? -44.936 1.872   34.924  1   40.35  ? 150 ARG C CA  1 
ATOM   5805 C  C   . ARG C 1 154 ? -45.641 1.191   33.758  1   40.04  ? 150 ARG C C   1 
ATOM   5806 O  O   . ARG C 1 154 ? -46.428 1.83    33.063  1   39.3   ? 150 ARG C O   1 
ATOM   5807 C  CB  . ARG C 1 154 ? -45.892 1.796   36.117  1   42.02  ? 150 ARG C CB  1 
ATOM   5808 C  CG  . ARG C 1 154 ? -45.483 0.748   37.135  1   43.9   ? 150 ARG C CG  1 
ATOM   5809 C  CD  . ARG C 1 154 ? -46.728 0.035   37.598  1   43.96  ? 150 ARG C CD  1 
ATOM   5810 N  NE  . ARG C 1 154 ? -46.471 -0.324  38.997  1   44.72  ? 150 ARG C NE  1 
ATOM   5811 C  CZ  . ARG C 1 154 ? -46.225 -1.55   39.398  1   45.73  ? 150 ARG C CZ  1 
ATOM   5812 N  NH1 . ARG C 1 154 ? -46.022 -1.794  40.688  1   45.8   ? 150 ARG C NH1 1 
ATOM   5813 N  NH2 . ARG C 1 154 ? -46.204 -2.529  38.503  1   46.86  ? 150 ARG C NH2 1 
ATOM   5814 N  N   . ALA C 1 155 ? -45.335 -0.095  33.547  1   38.96  ? 151 ALA C N   1 
ATOM   5815 C  CA  . ALA C 1 155 ? -46.024 -0.903  32.555  1   39.58  ? 151 ALA C CA  1 
ATOM   5816 C  C   . ALA C 1 155 ? -47.255 -1.504  33.225  1   42.31  ? 151 ALA C C   1 
ATOM   5817 O  O   . ALA C 1 155 ? -47.107 -2.243  34.182  1   46.81  ? 151 ALA C O   1 
ATOM   5818 C  CB  . ALA C 1 155 ? -45.089 -1.99   32.079  1   36.87  ? 151 ALA C CB  1 
ATOM   5819 N  N   . PHE C 1 156 ? -48.465 -1.205  32.739  1   42.58  ? 152 PHE C N   1 
ATOM   5820 C  CA  . PHE C 1 156 ? -49.651 -1.68   33.452  1   44.83  ? 152 PHE C CA  1 
ATOM   5821 C  C   . PHE C 1 156 ? -50.228 -2.974  32.858  1   46.82  ? 152 PHE C C   1 
ATOM   5822 O  O   . PHE C 1 156 ? -49.954 -3.32   31.722  1   47.65  ? 152 PHE C O   1 
ATOM   5823 C  CB  . PHE C 1 156 ? -50.67  -0.539  33.532  1   42.47  ? 152 PHE C CB  1 
ATOM   5824 C  CG  . PHE C 1 156 ? -51.205 -0.023  32.204  1   41.8   ? 152 PHE C CG  1 
ATOM   5825 C  CD1 . PHE C 1 156 ? -50.576 1.037   31.554  1   41.97  ? 152 PHE C CD1 1 
ATOM   5826 C  CD2 . PHE C 1 156 ? -52.359 -0.556  31.635  1   42.74  ? 152 PHE C CD2 1 
ATOM   5827 C  CE1 . PHE C 1 156 ? -51.081 1.547   30.364  1   41.72  ? 152 PHE C CE1 1 
ATOM   5828 C  CE2 . PHE C 1 156 ? -52.854 -0.055  30.434  1   42.95  ? 152 PHE C CE2 1 
ATOM   5829 C  CZ  . PHE C 1 156 ? -52.213 0.989   29.799  1   42.43  ? 152 PHE C CZ  1 
ATOM   5830 N  N   . GLY C 1 157 ? -51.057 -3.695  33.627  1   49.21  ? 153 GLY C N   1 
ATOM   5831 C  CA  . GLY C 1 157 ? -51.797 -4.839  33.101  1   52.51  ? 153 GLY C CA  1 
ATOM   5832 C  C   . GLY C 1 157 ? -53.218 -4.425  32.708  1   57.19  ? 153 GLY C C   1 
ATOM   5833 O  O   . GLY C 1 157 ? -53.627 -3.303  33.02   1   57.82  ? 153 GLY C O   1 
ATOM   5834 N  N   . VAL C 1 158 ? -53.955 -5.307  32.008  1   56.67  ? 154 VAL C N   1 
ATOM   5835 C  CA  . VAL C 1 158 ? -55.341 -5.038  31.625  1   56.43  ? 154 VAL C CA  1 
ATOM   5836 C  C   . VAL C 1 158 ? -56.255 -6.15   32.156  1   60.55  ? 154 VAL C C   1 
ATOM   5837 O  O   . VAL C 1 158 ? -56.198 -7.283  31.673  1   64.35  ? 154 VAL C O   1 
ATOM   5838 C  CB  . VAL C 1 158 ? -55.492 -4.889  30.101  1   55.01  ? 154 VAL C CB  1 
ATOM   5839 C  CG1 . VAL C 1 158 ? -56.934 -4.616  29.698  1   58.07  ? 154 VAL C CG1 1 
ATOM   5840 C  CG2 . VAL C 1 158 ? -54.533 -3.86   29.523  1   51.95  ? 154 VAL C CG2 1 
ATOM   5841 N  N   . PRO C 1 159 ? -57.096 -5.936  33.201  1   60.42  ? 155 PRO C N   1 
ATOM   5842 C  CA  . PRO C 1 159 ? -57.265 -4.638  33.829  1   59.42  ? 155 PRO C CA  1 
ATOM   5843 C  C   . PRO C 1 159 ? -56.143 -4.249  34.768  1   58.76  ? 155 PRO C C   1 
ATOM   5844 O  O   . PRO C 1 159 ? -55.278 -5.078  35.088  1   62.01  ? 155 PRO C O   1 
ATOM   5845 C  CB  . PRO C 1 159 ? -58.58  -4.841  34.575  1   59.51  ? 155 PRO C CB  1 
ATOM   5846 C  CG  . PRO C 1 159 ? -58.48  -6.243  35.086  1   61.82  ? 155 PRO C CG  1 
ATOM   5847 C  CD  . PRO C 1 159 ? -57.945 -6.943  33.861  1   61.46  ? 155 PRO C CD  1 
ATOM   5848 N  N   . VAL C 1 160 ? -56.17  -3.006  35.225  1   54.78  ? 156 VAL C N   1 
ATOM   5849 C  CA  . VAL C 1 160 ? -55.064 -2.49   36.073  1   53.9   ? 156 VAL C CA  1 
ATOM   5850 C  C   . VAL C 1 160 ? -55.197 -3.02   37.505  1   56.82  ? 156 VAL C C   1 
ATOM   5851 O  O   . VAL C 1 160 ? -56.319 -3.37   37.908  1   60.11  ? 156 VAL C O   1 
ATOM   5852 C  CB  . VAL C 1 160 ? -55.068 -0.949  36.023  1   49.92  ? 156 VAL C CB  1 
ATOM   5853 C  CG1 . VAL C 1 160 ? -55.048 -0.42   34.596  1   48.27  ? 156 VAL C CG1 1 
ATOM   5854 C  CG2 . VAL C 1 160 ? -56.211 -0.337  36.82   1   48.54  ? 156 VAL C CG2 1 
ATOM   5855 N  N   . ARG C 1 161 ? -54.068 -3.104  38.217  1   57.07  ? 157 ARG C N   1 
ATOM   5856 C  CA  . ARG C 1 161 ? -54.101 -3.497  39.645  1   59.7   ? 157 ARG C CA  1 
ATOM   5857 C  C   . ARG C 1 161 ? -53.677 -2.264  40.459  1   58.75  ? 157 ARG C C   1 
ATOM   5858 O  O   . ARG C 1 161 ? -53.348 -1.237  39.844  1   58.87  ? 157 ARG C O   1 
ATOM   5859 C  CB  . ARG C 1 161 ? -53.227 -4.738  39.848  1   62.43  ? 157 ARG C CB  1 
ATOM   5860 C  CG  . ARG C 1 161 ? -51.737 -4.524  40.046  1   67.54  ? 157 ARG C CG  1 
ATOM   5861 C  CD  . ARG C 1 161 ? -51.133 -5.74   40.717  1   73.17  ? 157 ARG C CD  1 
ATOM   5862 N  NE  . ARG C 1 161 ? -49.736 -5.497  41.085  1   70.44  ? 157 ARG C NE  1 
ATOM   5863 C  CZ  . ARG C 1 161 ? -48.743 -5.484  40.215  1   67.93  ? 157 ARG C CZ  1 
ATOM   5864 N  NH1 . ARG C 1 161 ? -48.752 -6.317  39.193  1   59.01  ? 157 ARG C NH1 1 
ATOM   5865 N  NH2 . ARG C 1 161 ? -47.747 -4.637  40.371  1   71.43  ? 157 ARG C NH2 1 
ATOM   5866 N  N   . THR C 1 162 ? -53.741 -2.348  41.786  1   56.98  ? 158 THR C N   1 
ATOM   5867 C  CA  . THR C 1 162 ? -53.34  -1.206  42.624  1   57.53  ? 158 THR C CA  1 
ATOM   5868 C  C   . THR C 1 162 ? -51.894 -0.889  42.313  1   54.78  ? 158 THR C C   1 
ATOM   5869 O  O   . THR C 1 162 ? -51.071 -1.815  42.347  1   58.83  ? 158 THR C O   1 
ATOM   5870 C  CB  . THR C 1 162 ? -53.587 -1.513  44.1    1   59.39  ? 158 THR C CB  1 
ATOM   5871 O  OG1 . THR C 1 162 ? -54.984 -1.76   44.193  1   59.92  ? 158 THR C OG1 1 
ATOM   5872 C  CG2 . THR C 1 162 ? -53.192 -0.368  45.014  1   52.04  ? 158 THR C CG2 1 
ATOM   5873 N  N   . TYR C 1 163 ? -51.599 0.377   41.997  1   50.02  ? 159 TYR C N   1 
ATOM   5874 C  CA  . TYR C 1 163 ? -50.178 0.749   41.749  1   44.98  ? 159 TYR C CA  1 
ATOM   5875 C  C   . TYR C 1 163 ? -49.717 1.682   42.87   1   44.31  ? 159 TYR C C   1 
ATOM   5876 O  O   . TYR C 1 163 ? -50.527 1.984   43.774  1   44.4   ? 159 TYR C O   1 
ATOM   5877 C  CB  . TYR C 1 163 ? -50.032 1.337   40.342  1   44.02  ? 159 TYR C CB  1 
ATOM   5878 C  CG  . TYR C 1 163 ? -50.376 0.339   39.247  1   47.47  ? 159 TYR C CG  1 
ATOM   5879 C  CD1 . TYR C 1 163 ? -49.916 -0.971  39.307  1   49.16  ? 159 TYR C CD1 1 
ATOM   5880 C  CD2 . TYR C 1 163 ? -51.172 0.699   38.167  1   47.11  ? 159 TYR C CD2 1 
ATOM   5881 C  CE1 . TYR C 1 163 ? -50.226 -1.889  38.319  1   50.81  ? 159 TYR C CE1 1 
ATOM   5882 C  CE2 . TYR C 1 163 ? -51.493 -0.213  37.175  1   48.75  ? 159 TYR C CE2 1 
ATOM   5883 C  CZ  . TYR C 1 163 ? -51.021 -1.511  37.253  1   50.13  ? 159 TYR C CZ  1 
ATOM   5884 O  OH  . TYR C 1 163 ? -51.331 -2.42   36.283  1   56.41  ? 159 TYR C OH  1 
HETATM 5885 N  N   . TPO C 1 164 ? -48.458 2.128   42.824  1   43.95  ? 160 TPO C N   1 
HETATM 5886 C  CA  . TPO C 1 164 ? -47.928 2.95    43.906  1   43.34  ? 160 TPO C CA  1 
HETATM 5887 C  CB  . TPO C 1 164 ? -46.521 3.439   43.541  1   40.67  ? 160 TPO C CB  1 
HETATM 5888 C  CG2 . TPO C 1 164 ? -45.865 4.267   44.625  1   38.61  ? 160 TPO C CG2 1 
HETATM 5889 O  OG1 . TPO C 1 164 ? -45.711 2.253   43.296  1   39.97  ? 160 TPO C OG1 1 
HETATM 5890 P  P   . TPO C 1 164 ? -45.207 1.867   41.8    1   40.65  ? 160 TPO C P   1 
HETATM 5891 O  O1P . TPO C 1 164 ? -46.479 1.584   40.985  1   41.56  ? 160 TPO C O1P 1 
HETATM 5892 O  O2P . TPO C 1 164 ? -44.331 0.639   41.994  1   40.16  ? 160 TPO C O2P 1 
HETATM 5893 O  O3P . TPO C 1 164 ? -44.426 3.027   41.27   1   36.57  ? 160 TPO C O3P 1 
HETATM 5894 C  C   . TPO C 1 164 ? -48.8   4.188   44.106  1   44.64  ? 160 TPO C C   1 
HETATM 5895 O  O   . TPO C 1 164 ? -49.2   4.81    43.125  1   43.22  ? 160 TPO C O   1 
ATOM   5896 N  N   . HIS C 1 165 ? -49.058 4.562   45.368  1   50.39  ? 161 HIS C N   1 
ATOM   5897 C  CA  . HIS C 1 165 ? -49.92  5.705   45.675  1   53.97  ? 161 HIS C CA  1 
ATOM   5898 C  C   . HIS C 1 165 ? -49.209 7.04    45.43   1   53.99  ? 161 HIS C C   1 
ATOM   5899 O  O   . HIS C 1 165 ? -49.817 7.975   44.91   1   51.6   ? 161 HIS C O   1 
ATOM   5900 C  CB  . HIS C 1 165 ? -50.529 5.589   47.081  1   58.77  ? 161 HIS C CB  1 
ATOM   5901 C  CG  . HIS C 1 165 ? -51.061 6.88    47.653  1   67.93  ? 161 HIS C CG  1 
ATOM   5902 N  ND1 . HIS C 1 165 ? -52.217 7.49    47.205  1   69.11  ? 161 HIS C ND1 1 
ATOM   5903 C  CD2 . HIS C 1 165 ? -50.572 7.693   48.621  1   67.37  ? 161 HIS C CD2 1 
ATOM   5904 C  CE1 . HIS C 1 165 ? -52.412 8.616   47.882  1   68.87  ? 161 HIS C CE1 1 
ATOM   5905 N  NE2 . HIS C 1 165 ? -51.427 8.758   48.746  1   69.1   ? 161 HIS C NE2 1 
ATOM   5906 N  N   . GLU C 1 166 ? -47.921 7.116   45.809  1   58.56  ? 162 GLU C N   1 
ATOM   5907 C  CA  . GLU C 1 166 ? -47.112 8.33    45.745  1   59.37  ? 162 GLU C CA  1 
ATOM   5908 C  C   . GLU C 1 166 ? -46.714 8.594   44.289  1   58.63  ? 162 GLU C C   1 
ATOM   5909 O  O   . GLU C 1 166 ? -45.584 8.286   43.899  1   60.73  ? 162 GLU C O   1 
ATOM   5910 C  CB  . GLU C 1 166 ? -45.804 8.228   46.548  1   57.21  ? 162 GLU C CB  1 
ATOM   5911 C  CG  . GLU C 1 166 ? -45.948 7.992   48.053  1   63.9   ? 162 GLU C CG  1 
ATOM   5912 C  CD  . GLU C 1 166 ? -46.598 6.708   48.569  1   66.96  ? 162 GLU C CD  1 
ATOM   5913 O  OE1 . GLU C 1 166 ? -46.22  5.606   48.095  1   67.03  ? 162 GLU C OE1 1 
ATOM   5914 O  OE2 . GLU C 1 166 ? -47.475 6.801   49.469  1   65.6   ? 162 GLU C OE2 1 
ATOM   5915 N  N   . VAL C 1 167 ? -47.624 9.178   43.49   1   53.85  ? 163 VAL C N   1 
ATOM   5916 C  CA  . VAL C 1 167 ? -47.318 9.429   42.082  1   53.56  ? 163 VAL C CA  1 
ATOM   5917 C  C   . VAL C 1 167 ? -47.867 10.79   41.653  1   53.14  ? 163 VAL C C   1 
ATOM   5918 O  O   . VAL C 1 167 ? -48.919 11.22   42.156  1   53.56  ? 163 VAL C O   1 
ATOM   5919 C  CB  . VAL C 1 167 ? -47.836 8.303   41.161  1   48.81  ? 163 VAL C CB  1 
ATOM   5920 C  CG1 . VAL C 1 167 ? -47.095 7.004   41.437  1   45.86  ? 163 VAL C CG1 1 
ATOM   5921 C  CG2 . VAL C 1 167 ? -49.35  8.101   41.271  1   43.74  ? 163 VAL C CG2 1 
ATOM   5922 N  N   . VAL C 1 168 ? -47.163 11.453  40.736  1   47.77  ? 164 VAL C N   1 
ATOM   5923 C  CA  . VAL C 1 168 ? -47.586 12.782  40.184  1   46.18  ? 164 VAL C CA  1 
ATOM   5924 C  C   . VAL C 1 168 ? -47.378 13.9    41.221  1   43.52  ? 164 VAL C C   1 
ATOM   5925 O  O   . VAL C 1 168 ? -47.854 13.77   42.354  1   42.96  ? 164 VAL C O   1 
ATOM   5926 C  CB  . VAL C 1 168 ? -49     12.867  39.553  1   45.37  ? 164 VAL C CB  1 
ATOM   5927 C  CG1 . VAL C 1 168 ? -49.092 13.998  38.544  1   43.55  ? 164 VAL C CG1 1 
ATOM   5928 C  CG2 . VAL C 1 168 ? -49.444 11.566  38.898  1   45.9   ? 164 VAL C CG2 1 
ATOM   5929 N  N   . THR C 1 169 ? -46.692 14.966  40.825  1   43.08  ? 165 THR C N   1 
ATOM   5930 C  CA  . THR C 1 169 ? -46.545 16.146  41.688  1   45.73  ? 165 THR C CA  1 
ATOM   5931 C  C   . THR C 1 169 ? -47.93  16.659  42.015  1   46.02  ? 165 THR C C   1 
ATOM   5932 O  O   . THR C 1 169 ? -48.734 16.781  41.079  1   41.54  ? 165 THR C O   1 
ATOM   5933 C  CB  . THR C 1 169 ? -45.699 17.159  40.923  1   47.56  ? 165 THR C CB  1 
ATOM   5934 O  OG1 . THR C 1 169 ? -44.44  16.521  40.745  1   51.05  ? 165 THR C OG1 1 
ATOM   5935 C  CG2 . THR C 1 169 ? -45.534 18.471  41.667  1   50.78  ? 165 THR C CG2 1 
ATOM   5936 N  N   . LEU C 1 170 ? -48.202 16.967  43.283  1   42.01  ? 166 LEU C N   1 
ATOM   5937 C  CA  . LEU C 1 170 ? -49.55  17.381  43.756  1   41.02  ? 166 LEU C CA  1 
ATOM   5938 C  C   . LEU C 1 170 ? -50.355 18.184  42.728  1   40.58  ? 166 LEU C C   1 
ATOM   5939 O  O   . LEU C 1 170 ? -51.483 17.784  42.443  1   42.18  ? 166 LEU C O   1 
ATOM   5940 C  CB  . LEU C 1 170 ? -49.342 18.181  45.041  1   38.68  ? 166 LEU C CB  1 
ATOM   5941 C  CG  . LEU C 1 170 ? -50.602 18.528  45.836  1   39.98  ? 166 LEU C CG  1 
ATOM   5942 C  CD1 . LEU C 1 170 ? -51.131 17.33   46.589  1   39.63  ? 166 LEU C CD1 1 
ATOM   5943 C  CD2 . LEU C 1 170 ? -50.331 19.681  46.777  1   37.83  ? 166 LEU C CD2 1 
ATOM   5944 N  N   . TRP C 1 171 ? -49.809 19.269  42.208  1   37.99  ? 167 TRP C N   1 
ATOM   5945 C  CA  . TRP C 1 171 ? -50.581 20.169  41.319  1   37.79  ? 167 TRP C CA  1 
ATOM   5946 C  C   . TRP C 1 171 ? -51.148 19.451  40.098  1   39.04  ? 167 TRP C C   1 
ATOM   5947 O  O   . TRP C 1 171 ? -52.131 19.944  39.537  1   41.75  ? 167 TRP C O   1 
ATOM   5948 C  CB  . TRP C 1 171 ? -49.694 21.347  40.912  1   36     ? 167 TRP C CB  1 
ATOM   5949 C  CG  . TRP C 1 171 ? -49.211 22.19   42.059  1   35.5   ? 167 TRP C CG  1 
ATOM   5950 C  CD1 . TRP C 1 171 ? -49.488 22.04   43.384  1   35.96  ? 167 TRP C CD1 1 
ATOM   5951 C  CD2 . TRP C 1 171 ? -48.349 23.34   41.957  1   33.72  ? 167 TRP C CD2 1 
ATOM   5952 N  NE1 . TRP C 1 171 ? -48.859 23.011  44.113  1   35.28  ? 167 TRP C NE1 1 
ATOM   5953 C  CE2 . TRP C 1 171 ? -48.155 23.823  43.266  1   34.22  ? 167 TRP C CE2 1 
ATOM   5954 C  CE3 . TRP C 1 171 ? -47.728 23.999  40.894  1   33.51  ? 167 TRP C CE3 1 
ATOM   5955 C  CZ2 . TRP C 1 171 ? -47.367 24.937  43.534  1   34.23  ? 167 TRP C CZ2 1 
ATOM   5956 C  CZ3 . TRP C 1 171 ? -46.951 25.101  41.161  1   33.71  ? 167 TRP C CZ3 1 
ATOM   5957 C  CH2 . TRP C 1 171 ? -46.775 25.561  42.463  1   33.52  ? 167 TRP C CH2 1 
ATOM   5958 N  N   . TYR C 1 172 ? -50.554 18.336  39.703  1   36.93  ? 168 TYR C N   1 
ATOM   5959 C  CA  . TYR C 1 172 ? -50.992 17.639  38.47   1   37.56  ? 168 TYR C CA  1 
ATOM   5960 C  C   . TYR C 1 172 ? -51.624 16.306  38.845  1   39.28  ? 168 TYR C C   1 
ATOM   5961 O  O   . TYR C 1 172 ? -52.05  15.584  37.939  1   39.06  ? 168 TYR C O   1 
ATOM   5962 C  CB  . TYR C 1 172 ? -49.727 17.605  37.61   1   34.95  ? 168 TYR C CB  1 
ATOM   5963 C  CG  . TYR C 1 172 ? -49.081 18.963  37.398  1   35.74  ? 168 TYR C CG  1 
ATOM   5964 C  CD1 . TYR C 1 172 ? -49.511 19.804  36.383  1   34.19  ? 168 TYR C CD1 1 
ATOM   5965 C  CD2 . TYR C 1 172 ? -48.05  19.403  38.218  1   34.47  ? 168 TYR C CD2 1 
ATOM   5966 C  CE1 . TYR C 1 172 ? -48.937 21.046  36.189  1   33.89  ? 168 TYR C CE1 1 
ATOM   5967 C  CE2 . TYR C 1 172 ? -47.472 20.646  38.038  1   35.74  ? 168 TYR C CE2 1 
ATOM   5968 C  CZ  . TYR C 1 172 ? -47.918 21.468  37.021  1   36.15  ? 168 TYR C CZ  1 
ATOM   5969 O  OH  . TYR C 1 172 ? -47.351 22.689  36.837  1   36.95  ? 168 TYR C OH  1 
ATOM   5970 N  N   . ARG C 1 173 ? -51.722 16.016  40.141  1   38.7   ? 169 ARG C N   1 
ATOM   5971 C  CA  . ARG C 1 173 ? -52.254 14.747  40.616  1   38.78  ? 169 ARG C CA  1 
ATOM   5972 C  C   . ARG C 1 173 ? -53.77  14.733  40.49   1   41.85  ? 169 ARG C C   1 
ATOM   5973 O  O   . ARG C 1 173 ? -54.447 15.603  41.043  1   46.03  ? 169 ARG C O   1 
ATOM   5974 C  CB  . ARG C 1 173 ? -51.835 14.618  42.082  1   38.73  ? 169 ARG C CB  1 
ATOM   5975 C  CG  . ARG C 1 173 ? -52.008 13.218  42.644  1   39.83  ? 169 ARG C CG  1 
ATOM   5976 C  CD  . ARG C 1 173 ? -51.541 13.142  44.079  1   38.83  ? 169 ARG C CD  1 
ATOM   5977 N  NE  . ARG C 1 173 ? -50.113 13.446  44.19   1   39.82  ? 169 ARG C NE  1 
ATOM   5978 C  CZ  . ARG C 1 173 ? -49.521 13.846  45.317  1   40.92  ? 169 ARG C CZ  1 
ATOM   5979 N  NH1 . ARG C 1 173 ? -50.232 14.031  46.43   1   41.53  ? 169 ARG C NH1 1 
ATOM   5980 N  NH2 . ARG C 1 173 ? -48.212 14.055  45.325  1   39.56  ? 169 ARG C NH2 1 
ATOM   5981 N  N   . ALA C 1 174 ? -54.297 13.72   39.791  1   43.06  ? 170 ALA C N   1 
ATOM   5982 C  CA  . ALA C 1 174 ? -55.732 13.56   39.566  1   44.03  ? 170 ALA C CA  1 
ATOM   5983 C  C   . ALA C 1 174 ? -56.475 13.254  40.866  1   47.7   ? 170 ALA C C   1 
ATOM   5984 O  O   . ALA C 1 174 ? -55.952 12.56   41.735  1   54.44  ? 170 ALA C O   1 
ATOM   5985 C  CB  . ALA C 1 174 ? -55.982 12.455  38.578  1   42.34  ? 170 ALA C CB  1 
ATOM   5986 N  N   . PRO C 1 175 ? -57.753 13.68   41.012  1   46.64  ? 171 PRO C N   1 
ATOM   5987 C  CA  . PRO C 1 175 ? -58.513 13.4    42.235  1   48.78  ? 171 PRO C CA  1 
ATOM   5988 C  C   . PRO C 1 175 ? -58.527 11.96   42.766  1   52.37  ? 171 PRO C C   1 
ATOM   5989 O  O   . PRO C 1 175 ? -58.496 11.75   43.981  1   50.97  ? 171 PRO C O   1 
ATOM   5990 C  CB  . PRO C 1 175 ? -59.904 13.883  41.875  1   50.83  ? 171 PRO C CB  1 
ATOM   5991 C  CG  . PRO C 1 175 ? -59.903 13.986  40.368  1   50.2   ? 171 PRO C CG  1 
ATOM   5992 C  CD  . PRO C 1 175 ? -58.519 14.413  39.998  1   44.82  ? 171 PRO C CD  1 
ATOM   5993 N  N   . GLU C 1 176 ? -58.527 10.969  41.857  1   52.97  ? 172 GLU C N   1 
ATOM   5994 C  CA  . GLU C 1 176 ? -58.676 9.58    42.265  1   55.15  ? 172 GLU C CA  1 
ATOM   5995 C  C   . GLU C 1 176 ? -57.439 9.092   43.016  1   57.69  ? 172 GLU C C   1 
ATOM   5996 O  O   . GLU C 1 176 ? -57.516 8.124   43.78   1   62.45  ? 172 GLU C O   1 
ATOM   5997 C  CB  . GLU C 1 176 ? -59     8.641   41.105  1   56.28  ? 172 GLU C CB  1 
ATOM   5998 C  CG  . GLU C 1 176 ? -58.04  8.77    39.928  1   54.69  ? 172 GLU C CG  1 
ATOM   5999 C  CD  . GLU C 1 176 ? -58.465 9.717   38.829  1   53.62  ? 172 GLU C CD  1 
ATOM   6000 O  OE1 . GLU C 1 176 ? -59.106 10.736  39.157  1   51.94  ? 172 GLU C OE1 1 
ATOM   6001 O  OE2 . GLU C 1 176 ? -58.115 9.452   37.655  1   51.63  ? 172 GLU C OE2 1 
ATOM   6002 N  N   . ILE C 1 177 ? -56.297 9.758   42.779  1   55.89  ? 173 ILE C N   1 
ATOM   6003 C  CA  . ILE C 1 177 ? -55.063 9.481   43.505  1   49.32  ? 173 ILE C CA  1 
ATOM   6004 C  C   . ILE C 1 177 ? -55.091 10.227  44.833  1   49.65  ? 173 ILE C C   1 
ATOM   6005 O  O   . ILE C 1 177 ? -54.641 9.715   45.869  1   46.57  ? 173 ILE C O   1 
ATOM   6006 C  CB  . ILE C 1 177 ? -53.831 9.909   42.692  1   46.64  ? 173 ILE C CB  1 
ATOM   6007 C  CG1 . ILE C 1 177 ? -53.796 9.236   41.327  1   45.85  ? 173 ILE C CG1 1 
ATOM   6008 C  CG2 . ILE C 1 177 ? -52.541 9.667   43.486  1   43.51  ? 173 ILE C CG2 1 
ATOM   6009 C  CD1 . ILE C 1 177 ? -52.606 9.664   40.492  1   45.57  ? 173 ILE C CD1 1 
ATOM   6010 N  N   . LEU C 1 178 ? -55.591 11.47   44.771  1   48.33  ? 174 LEU C N   1 
ATOM   6011 C  CA  . LEU C 1 178 ? -55.696 12.277  45.972  1   48.3   ? 174 LEU C CA  1 
ATOM   6012 C  C   . LEU C 1 178 ? -56.531 11.544  47.012  1   50.06  ? 174 LEU C C   1 
ATOM   6013 O  O   . LEU C 1 178 ? -56.149 11.521  48.183  1   48.26  ? 174 LEU C O   1 
ATOM   6014 C  CB  . LEU C 1 178 ? -56.288 13.643  45.65   1   47.56  ? 174 LEU C CB  1 
ATOM   6015 C  CG  . LEU C 1 178 ? -55.293 14.646  45.079  1   45.78  ? 174 LEU C CG  1 
ATOM   6016 C  CD1 . LEU C 1 178 ? -56.051 15.841  44.534  1   49.65  ? 174 LEU C CD1 1 
ATOM   6017 C  CD2 . LEU C 1 178 ? -54.296 15.014  46.174  1   44.12  ? 174 LEU C CD2 1 
ATOM   6018 N  N   . LEU C 1 179 ? -57.653 10.96   46.548  1   53.38  ? 175 LEU C N   1 
ATOM   6019 C  CA  . LEU C 1 179 ? -58.676 10.364  47.4    1   56.74  ? 175 LEU C CA  1 
ATOM   6020 C  C   . LEU C 1 179 ? -58.274 8.957   47.826  1   58.82  ? 175 LEU C C   1 
ATOM   6021 O  O   . LEU C 1 179 ? -58.819 8.439   48.795  1   61.8   ? 175 LEU C O   1 
ATOM   6022 C  CB  . LEU C 1 179 ? -60.034 10.427  46.706  1   54.8   ? 175 LEU C CB  1 
ATOM   6023 C  CG  . LEU C 1 179 ? -60.558 11.856  46.544  1   55.38  ? 175 LEU C CG  1 
ATOM   6024 C  CD1 . LEU C 1 179 ? -61.739 11.935  45.625  1   55.39  ? 175 LEU C CD1 1 
ATOM   6025 C  CD2 . LEU C 1 179 ? -60.905 12.457  47.906  1   58.75  ? 175 LEU C CD2 1 
ATOM   6026 N  N   . GLY C 1 180 ? -57.293 8.375   47.118  1   56.94  ? 176 GLY C N   1 
ATOM   6027 C  CA  . GLY C 1 180 ? -56.713 7.091   47.474  1   56.4   ? 176 GLY C CA  1 
ATOM   6028 C  C   . GLY C 1 180 ? -57.571 5.924   46.992  1   58.72  ? 176 GLY C C   1 
ATOM   6029 O  O   . GLY C 1 180 ? -57.726 4.929   47.704  1   59.14  ? 176 GLY C O   1 
ATOM   6030 N  N   . CYS C 1 181 ? -58.11  6.056   45.774  1   59.21  ? 177 CYS C N   1 
ATOM   6031 C  CA  . CYS C 1 181 ? -58.905 5.004   45.164  1   60.97  ? 177 CYS C CA  1 
ATOM   6032 C  C   . CYS C 1 181 ? -58.028 3.794   44.9    1   62.23  ? 177 CYS C C   1 
ATOM   6033 O  O   . CYS C 1 181 ? -56.939 3.946   44.353  1   64.62  ? 177 CYS C O   1 
ATOM   6034 C  CB  . CYS C 1 181 ? -59.453 5.454   43.82   1   59.2   ? 177 CYS C CB  1 
ATOM   6035 S  SG  . CYS C 1 181 ? -60.716 6.73    44.04   1   63.54  ? 177 CYS C SG  1 
ATOM   6036 N  N   . LYS C 1 182 ? -58.531 2.612   45.278  1   63.41  ? 178 LYS C N   1 
ATOM   6037 C  CA  . LYS C 1 182 ? -57.84  1.346   45.069  1   62.53  ? 178 LYS C CA  1 
ATOM   6038 C  C   . LYS C 1 182 ? -57.124 1.328   43.713  1   58.83  ? 178 LYS C C   1 
ATOM   6039 O  O   . LYS C 1 182 ? -55.958 0.955   43.625  1   58.78  ? 178 LYS C O   1 
ATOM   6040 C  CB  . LYS C 1 182 ? -58.793 0.152   45.205  1   62.16  ? 178 LYS C CB  1 
ATOM   6041 C  CG  . LYS C 1 182 ? -58.12  -1.189  45.434  1   62.79  ? 178 LYS C CG  1 
ATOM   6042 C  CD  . LYS C 1 182 ? -59.187 -2.266  45.557  1   68.59  ? 178 LYS C CD  1 
ATOM   6043 C  CE  . LYS C 1 182 ? -58.72  -3.633  45.952  1   69.41  ? 178 LYS C CE  1 
ATOM   6044 N  NZ  . LYS C 1 182 ? -59.887 -4.459  46.3    1   71.5   ? 178 LYS C NZ  1 
ATOM   6045 N  N   . TYR C 1 183 ? -57.82  1.73    42.649  1   54.92  ? 179 TYR C N   1 
ATOM   6046 C  CA  . TYR C 1 183 ? -57.252 1.598   41.322  1   52.02  ? 179 TYR C CA  1 
ATOM   6047 C  C   . TYR C 1 183 ? -57.201 2.97    40.668  1   52.46  ? 179 TYR C C   1 
ATOM   6048 O  O   . TYR C 1 183 ? -58.01  3.842   41.007  1   53.65  ? 179 TYR C O   1 
ATOM   6049 C  CB  . TYR C 1 183 ? -58.16  0.722   40.454  1   53.6   ? 179 TYR C CB  1 
ATOM   6050 C  CG  . TYR C 1 183 ? -58.397 -0.694  40.947  1   54.51  ? 179 TYR C CG  1 
ATOM   6051 C  CD1 . TYR C 1 183 ? -57.336 -1.508  41.332  1   53.78  ? 179 TYR C CD1 1 
ATOM   6052 C  CD2 . TYR C 1 183 ? -59.679 -1.214  41.044  1   56.6   ? 179 TYR C CD2 1 
ATOM   6053 C  CE1 . TYR C 1 183 ? -57.535 -2.804  41.786  1   53.68  ? 179 TYR C CE1 1 
ATOM   6054 C  CE2 . TYR C 1 183 ? -59.889 -2.505  41.508  1   58.41  ? 179 TYR C CE2 1 
ATOM   6055 C  CZ  . TYR C 1 183 ? -58.817 -3.302  41.877  1   56.42  ? 179 TYR C CZ  1 
ATOM   6056 O  OH  . TYR C 1 183 ? -59.029 -4.572  42.321  1   58.49  ? 179 TYR C OH  1 
ATOM   6057 N  N   . TYR C 1 184 ? -56.245 3.125   39.734  1   49.94  ? 180 TYR C N   1 
ATOM   6058 C  CA  . TYR C 1 184 ? -56.193 4.229   38.79   1   47.96  ? 180 TYR C CA  1 
ATOM   6059 C  C   . TYR C 1 184 ? -55.442 3.802   37.531  1   48.93  ? 180 TYR C C   1 
ATOM   6060 O  O   . TYR C 1 184 ? -54.661 2.851   37.553  1   54.46  ? 180 TYR C O   1 
ATOM   6061 C  CB  . TYR C 1 184 ? -55.522 5.441   39.421  1   46.49  ? 180 TYR C CB  1 
ATOM   6062 C  CG  . TYR C 1 184 ? -54.045 5.216   39.688  1   46.91  ? 180 TYR C CG  1 
ATOM   6063 C  CD1 . TYR C 1 184 ? -53.119 5.245   38.652  1   45     ? 180 TYR C CD1 1 
ATOM   6064 C  CD2 . TYR C 1 184 ? -53.584 4.976   40.979  1   48.13  ? 180 TYR C CD2 1 
ATOM   6065 C  CE1 . TYR C 1 184 ? -51.772 5.047   38.895  1   43.29  ? 180 TYR C CE1 1 
ATOM   6066 C  CE2 . TYR C 1 184 ? -52.246 4.756   41.235  1   45.18  ? 180 TYR C CE2 1 
ATOM   6067 C  CZ  . TYR C 1 184 ? -51.339 4.807   40.189  1   44.85  ? 180 TYR C CZ  1 
ATOM   6068 O  OH  . TYR C 1 184 ? -50.011 4.618   40.463  1   46.54  ? 180 TYR C OH  1 
ATOM   6069 N  N   . SER C 1 185 ? -55.66  4.551   36.445  1   46.55  ? 181 SER C N   1 
ATOM   6070 C  CA  . SER C 1 185 ? -55.368 4.107   35.096  1   44.91  ? 181 SER C CA  1 
ATOM   6071 C  C   . SER C 1 185 ? -54.849 5.291   34.284  1   44.07  ? 181 SER C C   1 
ATOM   6072 O  O   . SER C 1 185 ? -54.406 6.275   34.873  1   45.74  ? 181 SER C O   1 
ATOM   6073 C  CB  . SER C 1 185 ? -56.618 3.486   34.488  1   48.81  ? 181 SER C CB  1 
ATOM   6074 O  OG  . SER C 1 185 ? -56.416 2.977   33.17   1   49.55  ? 181 SER C OG  1 
ATOM   6075 N  N   . THR C 1 186 ? -54.918 5.173   32.948  1   43.67  ? 182 THR C N   1 
ATOM   6076 C  CA  . THR C 1 186 ? -54.449 6.123   31.947  1   43.41  ? 182 THR C CA  1 
ATOM   6077 C  C   . THR C 1 186 ? -55.043 7.505   32.191  1   46.5   ? 182 THR C C   1 
ATOM   6078 O  O   . THR C 1 186 ? -54.45  8.517   31.805  1   50.35  ? 182 THR C O   1 
ATOM   6079 C  CB  . THR C 1 186 ? -54.838 5.648   30.544  1   44.85  ? 182 THR C CB  1 
ATOM   6080 O  OG1 . THR C 1 186 ? -56.098 4.996   30.656  1   47.06  ? 182 THR C OG1 1 
ATOM   6081 C  CG2 . THR C 1 186 ? -53.883 4.628   29.952  1   44.54  ? 182 THR C CG2 1 
ATOM   6082 N  N   . ALA C 1 187 ? -56.239 7.534   32.786  1   46.12  ? 183 ALA C N   1 
ATOM   6083 C  CA  . ALA C 1 187 ? -56.92  8.77    33.132  1   47.2   ? 183 ALA C CA  1 
ATOM   6084 C  C   . ALA C 1 187 ? -56.03  9.733   33.94   1   47.68  ? 183 ALA C C   1 
ATOM   6085 O  O   . ALA C 1 187 ? -56.147 10.946  33.784  1   51.6   ? 183 ALA C O   1 
ATOM   6086 C  CB  . ALA C 1 187 ? -58.211 8.448   33.849  1   46.58  ? 183 ALA C CB  1 
ATOM   6087 N  N   . VAL C 1 188 ? -55.12  9.225   34.78   1   46.08  ? 184 VAL C N   1 
ATOM   6088 C  CA  . VAL C 1 188 ? -54.325 10.1    35.629  1   45.34  ? 184 VAL C CA  1 
ATOM   6089 C  C   . VAL C 1 188 ? -53.366 10.953  34.789  1   46.92  ? 184 VAL C C   1 
ATOM   6090 O  O   . VAL C 1 188 ? -53.029 12.069  35.176  1   53.08  ? 184 VAL C O   1 
ATOM   6091 C  CB  . VAL C 1 188 ? -53.592 9.395   36.79   1   46.13  ? 184 VAL C CB  1 
ATOM   6092 C  CG1 . VAL C 1 188 ? -54.51  8.517   37.645  1   43.91  ? 184 VAL C CG1 1 
ATOM   6093 C  CG2 . VAL C 1 188 ? -52.376 8.613   36.316  1   43.07  ? 184 VAL C CG2 1 
ATOM   6094 N  N   . ASP C 1 189 ? -52.946 10.468  33.62   1   46.51  ? 185 ASP C N   1 
ATOM   6095 C  CA  . ASP C 1 189 ? -52.04  11.253  32.794  1   46.3   ? 185 ASP C CA  1 
ATOM   6096 C  C   . ASP C 1 189 ? -52.78  12.342  32.02   1   47.52  ? 185 ASP C C   1 
ATOM   6097 O  O   . ASP C 1 189 ? -52.231 13.42   31.789  1   48.55  ? 185 ASP C O   1 
ATOM   6098 C  CB  . ASP C 1 189 ? -51.307 10.372  31.804  1   46.37  ? 185 ASP C CB  1 
ATOM   6099 C  CG  . ASP C 1 189 ? -50.242 9.473   32.406  1   46.76  ? 185 ASP C CG  1 
ATOM   6100 O  OD1 . ASP C 1 189 ? -49.715 9.826   33.488  1   45.03  ? 185 ASP C OD1 1 
ATOM   6101 O  OD2 . ASP C 1 189 ? -49.972 8.413   31.787  1   47.18  ? 185 ASP C OD2 1 
ATOM   6102 N  N   . ILE C 1 190 ? -54     12.028  31.562  1   48.23  ? 186 ILE C N   1 
ATOM   6103 C  CA  . ILE C 1 190 ? -54.822 12.998  30.856  1   47.09  ? 186 ILE C CA  1 
ATOM   6104 C  C   . ILE C 1 190 ? -55.062 14.193  31.783  1   49.15  ? 186 ILE C C   1 
ATOM   6105 O  O   . ILE C 1 190 ? -54.944 15.352  31.385  1   50.63  ? 186 ILE C O   1 
ATOM   6106 C  CB  . ILE C 1 190 ? -56.136 12.344  30.375  1   48.46  ? 186 ILE C CB  1 
ATOM   6107 C  CG1 . ILE C 1 190 ? -55.893 11.43   29.169  1   48.12  ? 186 ILE C CG1 1 
ATOM   6108 C  CG2 . ILE C 1 190 ? -57.225 13.381  30.064  1   47.24  ? 186 ILE C CG2 1 
ATOM   6109 C  CD1 . ILE C 1 190 ? -55.477 12.17   27.909  1   47.21  ? 186 ILE C CD1 1 
ATOM   6110 N  N   . TRP C 1 191 ? -55.402 13.901  33.04   1   47.15  ? 187 TRP C N   1 
ATOM   6111 C  CA  . TRP C 1 191 ? -55.65  14.954  34.002  1   45.41  ? 187 TRP C CA  1 
ATOM   6112 C  C   . TRP C 1 191 ? -54.459 15.91   33.986  1   43.81  ? 187 TRP C C   1 
ATOM   6113 O  O   . TRP C 1 191 ? -54.609 17.132  33.936  1   42.27  ? 187 TRP C O   1 
ATOM   6114 C  CB  . TRP C 1 191 ? -55.854 14.345  35.395  1   44.73  ? 187 TRP C CB  1 
ATOM   6115 C  CG  . TRP C 1 191 ? -56.099 15.396  36.44   1   46.11  ? 187 TRP C CG  1 
ATOM   6116 C  CD1 . TRP C 1 191 ? -55.146 16.045  37.164  1   44.89  ? 187 TRP C CD1 1 
ATOM   6117 C  CD2 . TRP C 1 191 ? -57.372 15.959  36.836  1   47.35  ? 187 TRP C CD2 1 
ATOM   6118 N  NE1 . TRP C 1 191 ? -55.728 16.944  38.011  1   45.11  ? 187 TRP C NE1 1 
ATOM   6119 C  CE2 . TRP C 1 191 ? -57.09  16.923  37.826  1   48.02  ? 187 TRP C CE2 1 
ATOM   6120 C  CE3 . TRP C 1 191 ? -58.703 15.732  36.477  1   48.29  ? 187 TRP C CE3 1 
ATOM   6121 C  CZ2 . TRP C 1 191 ? -58.096 17.656  38.456  1   48.7   ? 187 TRP C CZ2 1 
ATOM   6122 C  CZ3 . TRP C 1 191 ? -59.686 16.474  37.092  1   51.21  ? 187 TRP C CZ3 1 
ATOM   6123 C  CH2 . TRP C 1 191 ? -59.391 17.419  38.071  1   49.64  ? 187 TRP C CH2 1 
ATOM   6124 N  N   . SER C 1 192 ? -53.263 15.317  34.001  1   42.72  ? 188 SER C N   1 
ATOM   6125 C  CA  . SER C 1 192 ? -52.045 16.101  34.082  1   41.16  ? 188 SER C CA  1 
ATOM   6126 C  C   . SER C 1 192 ? -51.909 16.979  32.832  1   41.14  ? 188 SER C C   1 
ATOM   6127 O  O   . SER C 1 192 ? -51.68  18.171  32.964  1   39.15  ? 188 SER C O   1 
ATOM   6128 C  CB  . SER C 1 192 ? -50.834 15.235  34.386  1   36.42  ? 188 SER C CB  1 
ATOM   6129 O  OG  . SER C 1 192 ? -51.04  14.494  35.583  1   32.64  ? 188 SER C OG  1 
ATOM   6130 N  N   . LEU C 1 193 ? -52.136 16.423  31.631  1   42.06  ? 189 LEU C N   1 
ATOM   6131 C  CA  . LEU C 1 193 ? -52.096 17.223  30.414  1   41.51  ? 189 LEU C CA  1 
ATOM   6132 C  C   . LEU C 1 193 ? -53.18  18.291  30.464  1   40.56  ? 189 LEU C C   1 
ATOM   6133 O  O   . LEU C 1 193 ? -53.005 19.372  29.91   1   39.5   ? 189 LEU C O   1 
ATOM   6134 C  CB  . LEU C 1 193 ? -52.22  16.409  29.13   1   42.36  ? 189 LEU C CB  1 
ATOM   6135 C  CG  . LEU C 1 193 ? -51.048 15.483  28.807  1   44.64  ? 189 LEU C CG  1 
ATOM   6136 C  CD1 . LEU C 1 193 ? -51.2   14.945  27.37   1   44.71  ? 189 LEU C CD1 1 
ATOM   6137 C  CD2 . LEU C 1 193 ? -49.739 16.23   29.005  1   40.67  ? 189 LEU C CD2 1 
ATOM   6138 N  N   . GLY C 1 194 ? -54.309 17.955  31.1    1   42.1   ? 190 GLY C N   1 
ATOM   6139 C  CA  . GLY C 1 194 ? -55.407 18.894  31.274  1   42.77  ? 190 GLY C CA  1 
ATOM   6140 C  C   . GLY C 1 194 ? -54.931 20.119  32.044  1   42.62  ? 190 GLY C C   1 
ATOM   6141 O  O   . GLY C 1 194 ? -55.105 21.25   31.599  1   44.35  ? 190 GLY C O   1 
ATOM   6142 N  N   . CYS C 1 195 ? -54.263 19.855  33.174  1   43.13  ? 191 CYS C N   1 
ATOM   6143 C  CA  . CYS C 1 195 ? -53.649 20.895  33.981  1   43.42  ? 191 CYS C CA  1 
ATOM   6144 C  C   . CYS C 1 195 ? -52.631 21.671  33.158  1   44.59  ? 191 CYS C C   1 
ATOM   6145 O  O   . CYS C 1 195 ? -52.57  22.894  33.266  1   47.14  ? 191 CYS C O   1 
ATOM   6146 C  CB  . CYS C 1 195 ? -52.95  20.316  35.2    1   41.54  ? 191 CYS C CB  1 
ATOM   6147 S  SG  . CYS C 1 195 ? -54.138 19.543  36.32   1   44.35  ? 191 CYS C SG  1 
ATOM   6148 N  N   . ILE C 1 196 ? -51.871 20.956  32.316  1   42.66  ? 192 ILE C N   1 
ATOM   6149 C  CA  . ILE C 1 196 ? -50.778 21.546  31.561  1   41.71  ? 192 ILE C CA  1 
ATOM   6150 C  C   . ILE C 1 196 ? -51.332 22.4    30.419  1   41.47  ? 192 ILE C C   1 
ATOM   6151 O  O   . ILE C 1 196 ? -50.766 23.454  30.131  1   42     ? 192 ILE C O   1 
ATOM   6152 C  CB  . ILE C 1 196 ? -49.738 20.481  31.138  1   42.12  ? 192 ILE C CB  1 
ATOM   6153 C  CG1 . ILE C 1 196 ? -49.013 19.925  32.372  1   37.41  ? 192 ILE C CG1 1 
ATOM   6154 C  CG2 . ILE C 1 196 ? -48.737 21.032  30.106  1   39.76  ? 192 ILE C CG2 1 
ATOM   6155 C  CD1 . ILE C 1 196 ? -48.456 18.529  32.171  1   36.82  ? 192 ILE C CD1 1 
ATOM   6156 N  N   . PHE C 1 197 ? -52.449 21.971  29.814  1   41.71  ? 193 PHE C N   1 
ATOM   6157 C  CA  . PHE C 1 197 ? -53.125 22.776  28.81   1   44.89  ? 193 PHE C CA  1 
ATOM   6158 C  C   . PHE C 1 197 ? -53.475 24.16   29.375  1   45.37  ? 193 PHE C C   1 
ATOM   6159 O  O   . PHE C 1 197 ? -53.051 25.193  28.85   1   45.57  ? 193 PHE C O   1 
ATOM   6160 C  CB  . PHE C 1 197 ? -54.364 21.989  28.387  1   47.26  ? 193 PHE C CB  1 
ATOM   6161 C  CG  . PHE C 1 197 ? -55.202 22.66   27.305  1   49.27  ? 193 PHE C CG  1 
ATOM   6162 C  CD1 . PHE C 1 197 ? -54.694 23.702  26.53   1   48.89  ? 193 PHE C CD1 1 
ATOM   6163 C  CD2 . PHE C 1 197 ? -56.506 22.244  27.058  1   50.88  ? 193 PHE C CD2 1 
ATOM   6164 C  CE1 . PHE C 1 197 ? -55.478 24.31   25.549  1   51.41  ? 193 PHE C CE1 1 
ATOM   6165 C  CE2 . PHE C 1 197 ? -57.282 22.865  26.079  1   53.27  ? 193 PHE C CE2 1 
ATOM   6166 C  CZ  . PHE C 1 197 ? -56.766 23.887  25.32   1   51.4   ? 193 PHE C CZ  1 
ATOM   6167 N  N   . ALA C 1 198 ? -54.238 24.17   30.472  1   42.93  ? 194 ALA C N   1 
ATOM   6168 C  CA  . ALA C 1 198 ? -54.61  25.403  31.148  1   42.42  ? 194 ALA C CA  1 
ATOM   6169 C  C   . ALA C 1 198 ? -53.391 26.26   31.498  1   43.82  ? 194 ALA C C   1 
ATOM   6170 O  O   . ALA C 1 198 ? -53.491 27.482  31.405  1   47.45  ? 194 ALA C O   1 
ATOM   6171 C  CB  . ALA C 1 198 ? -55.437 25.081  32.372  1   41.23  ? 194 ALA C CB  1 
ATOM   6172 N  N   . GLU C 1 199 ? -52.255 25.638  31.887  1   42.61  ? 195 GLU C N   1 
ATOM   6173 C  CA  . GLU C 1 199 ? -51.056 26.357  32.328  1   43.91  ? 195 GLU C CA  1 
ATOM   6174 C  C   . GLU C 1 199 ? -50.324 27.006  31.144  1   43.39  ? 195 GLU C C   1 
ATOM   6175 O  O   . GLU C 1 199 ? -49.641 28.022  31.315  1   42.8   ? 195 GLU C O   1 
ATOM   6176 C  CB  . GLU C 1 199 ? -50.128 25.489  33.19   1   43.17  ? 195 GLU C CB  1 
ATOM   6177 C  CG  . GLU C 1 199 ? -48.961 26.222  33.862  1   42.73  ? 195 GLU C CG  1 
ATOM   6178 C  CD  . GLU C 1 199 ? -48.085 25.378  34.792  1   42.46  ? 195 GLU C CD  1 
ATOM   6179 O  OE1 . GLU C 1 199 ? -48.514 24.225  35.043  1   39.24  ? 195 GLU C OE1 1 
ATOM   6180 O  OE2 . GLU C 1 199 ? -46.994 25.836  35.254  1   41.83  ? 195 GLU C OE2 1 
ATOM   6181 N  N   . MET C 1 200 ? -50.466 26.412  29.95   1   41.73  ? 196 MET C N   1 
ATOM   6182 C  CA  . MET C 1 200 ? -49.875 26.991  28.754  1   43.39  ? 196 MET C CA  1 
ATOM   6183 C  C   . MET C 1 200 ? -50.639 28.257  28.373  1   45.47  ? 196 MET C C   1 
ATOM   6184 O  O   . MET C 1 200 ? -50.103 29.132  27.722  1   52.13  ? 196 MET C O   1 
ATOM   6185 C  CB  . MET C 1 200 ? -49.872 26.01   27.574  1   42.36  ? 196 MET C CB  1 
ATOM   6186 C  CG  . MET C 1 200 ? -48.671 25.075  27.514  1   40.52  ? 196 MET C CG  1 
ATOM   6187 S  SD  . MET C 1 200 ? -48.556 24.02   26.046  1   41.4   ? 196 MET C SD  1 
ATOM   6188 C  CE  . MET C 1 200 ? -49.986 22.959  26.291  1   39.92  ? 196 MET C CE  1 
ATOM   6189 N  N   . VAL C 1 201 ? -51.9   28.36   28.782  1   46.6   ? 197 VAL C N   1 
ATOM   6190 C  CA  . VAL C 1 201 ? -52.734 29.481  28.391  1   46.98  ? 197 VAL C CA  1 
ATOM   6191 C  C   . VAL C 1 201 ? -52.418 30.661  29.31   1   48.38  ? 197 VAL C C   1 
ATOM   6192 O  O   . VAL C 1 201 ? -52.159 31.77   28.841  1   48.1   ? 197 VAL C O   1 
ATOM   6193 C  CB  . VAL C 1 201 ? -54.211 29.038  28.457  1   46.7   ? 197 VAL C CB  1 
ATOM   6194 C  CG1 . VAL C 1 201 ? -55.172 30.22   28.572  1   46.29  ? 197 VAL C CG1 1 
ATOM   6195 C  CG2 . VAL C 1 201 ? -54.572 28.125  27.28   1   46.46  ? 197 VAL C CG2 1 
ATOM   6196 N  N   . THR C 1 202 ? -52.367 30.378  30.617  1   45.88  ? 198 THR C N   1 
ATOM   6197 C  CA  . THR C 1 202 ? -52.237 31.402  31.638  1   46.01  ? 198 THR C CA  1 
ATOM   6198 C  C   . THR C 1 202 ? -50.778 31.562  32.071  1   44.83  ? 198 THR C C   1 
ATOM   6199 O  O   . THR C 1 202 ? -50.415 32.584  32.635  1   43.71  ? 198 THR C O   1 
ATOM   6200 C  CB  . THR C 1 202 ? -53.162 31.038  32.808  1   47.47  ? 198 THR C CB  1 
ATOM   6201 O  OG1 . THR C 1 202 ? -52.619 29.934  33.544  1   46.06  ? 198 THR C OG1 1 
ATOM   6202 C  CG2 . THR C 1 202 ? -54.585 30.743  32.351  1   45.02  ? 198 THR C CG2 1 
ATOM   6203 N  N   . ARG C 1 203 ? -49.946 30.533  31.865  1   47.17  ? 199 ARG C N   1 
ATOM   6204 C  CA  . ARG C 1 203 ? -48.56  30.533  32.34   1   49.64  ? 199 ARG C CA  1 
ATOM   6205 C  C   . ARG C 1 203 ? -48.53  30.551  33.869  1   49.73  ? 199 ARG C C   1 
ATOM   6206 O  O   . ARG C 1 203 ? -47.557 31.014  34.46   1   47.65  ? 199 ARG C O   1 
ATOM   6207 C  CB  . ARG C 1 203 ? -47.712 31.648  31.711  1   50.43  ? 199 ARG C CB  1 
ATOM   6208 C  CG  . ARG C 1 203 ? -47.822 31.62   30.19   1   54.85  ? 199 ARG C CG  1 
ATOM   6209 C  CD  . ARG C 1 203 ? -48.018 33.004  29.516  1   59.01  ? 199 ARG C CD  1 
ATOM   6210 N  NE  . ARG C 1 203 ? -49.347 33.631  29.546  1   56.76  ? 199 ARG C NE  1 
ATOM   6211 C  CZ  . ARG C 1 203 ? -49.529 34.913  29.806  1   63.87  ? 199 ARG C CZ  1 
ATOM   6212 N  NH1 . ARG C 1 203 ? -50.729 35.472  29.727  1   69.86  ? 199 ARG C NH1 1 
ATOM   6213 N  NH2 . ARG C 1 203 ? -48.488 35.66   30.115  1   67.16  ? 199 ARG C NH2 1 
ATOM   6214 N  N   A ARG C 1 204 ? -49.619 30.061  34.48   0.5 50.75  ? 200 ARG C N   1 
ATOM   6215 N  N   B ARG C 1 204 ? -49.619 30.051  34.476  0.5 49.21  ? 200 ARG C N   1 
ATOM   6216 C  CA  A ARG C 1 204 ? -49.714 29.805  35.909  0.5 51.51  ? 200 ARG C CA  1 
ATOM   6217 C  CA  B ARG C 1 204 ? -49.751 29.825  35.907  0.5 48.86  ? 200 ARG C CA  1 
ATOM   6218 C  C   A ARG C 1 204 ? -50.4   28.46   36.107  0.5 49.57  ? 200 ARG C C   1 
ATOM   6219 C  C   B ARG C 1 204 ? -50.403 28.46   36.105  0.5 48.06  ? 200 ARG C C   1 
ATOM   6220 O  O   A ARG C 1 204 ? -51.312 28.115  35.357  0.5 52.79  ? 200 ARG C O   1 
ATOM   6221 O  O   B ARG C 1 204 ? -51.297 28.094  35.343  0.5 51.34  ? 200 ARG C O   1 
ATOM   6222 C  CB  A ARG C 1 204 ? -50.636 30.8    36.612  0.5 54.02  ? 200 ARG C CB  1 
ATOM   6223 C  CB  B ARG C 1 204 ? -50.752 30.812  36.511  0.5 48.72  ? 200 ARG C CB  1 
ATOM   6224 C  CG  A ARG C 1 204 ? -50.1   32.215  36.73   0.5 56.55  ? 200 ARG C CG  1 
ATOM   6225 C  CG  B ARG C 1 204 ? -50.599 32.274  36.125  0.5 48.18  ? 200 ARG C CG  1 
ATOM   6226 C  CD  A ARG C 1 204 ? -51.111 33.054  37.485  0.5 58.56  ? 200 ARG C CD  1 
ATOM   6227 C  CD  B ARG C 1 204 ? -51.798 33.037  36.663  0.5 47.77  ? 200 ARG C CD  1 
ATOM   6228 N  NE  A ARG C 1 204 ? -50.72  34.447  37.261  0.5 62.46  ? 200 ARG C NE  1 
ATOM   6229 N  NE  B ARG C 1 204 ? -51.705 34.463  36.338  0.5 48.95  ? 200 ARG C NE  1 
ATOM   6230 C  CZ  A ARG C 1 204 ? -49.617 35.018  37.717  0.5 60.51  ? 200 ARG C CZ  1 
ATOM   6231 C  CZ  B ARG C 1 204 ? -52.55  35.104  35.546  0.5 49.14  ? 200 ARG C CZ  1 
ATOM   6232 N  NH1 A ARG C 1 204 ? -48.89  34.445  38.665  0.5 58.51  ? 200 ARG C NH1 1 
ATOM   6233 N  NH1 B ARG C 1 204 ? -53.534 34.421  34.974  0.5 48.51  ? 200 ARG C NH1 1 
ATOM   6234 N  NH2 A ARG C 1 204 ? -49.289 36.198  37.238  0.5 61.74  ? 200 ARG C NH2 1 
ATOM   6235 N  NH2 B ARG C 1 204 ? -52.391 36.403  35.33   0.5 48.67  ? 200 ARG C NH2 1 
ATOM   6236 N  N   . ALA C 1 205 ? -49.958 27.721  37.129  1   45.85  ? 201 ALA C N   1 
ATOM   6237 C  CA  . ALA C 1 205 ? -50.512 26.412  37.448  1   44.21  ? 201 ALA C CA  1 
ATOM   6238 C  C   . ALA C 1 205 ? -52.002 26.561  37.746  1   45.66  ? 201 ALA C C   1 
ATOM   6239 O  O   . ALA C 1 205 ? -52.406 27.528  38.412  1   49.57  ? 201 ALA C O   1 
ATOM   6240 C  CB  . ALA C 1 205 ? -49.757 25.811  38.619  1   41.76  ? 201 ALA C CB  1 
ATOM   6241 N  N   . LEU C 1 206 ? -52.798 25.617  37.218  1   42.71  ? 202 LEU C N   1 
ATOM   6242 C  CA  . LEU C 1 206 ? -54.242 25.614  37.402  1   41.18  ? 202 LEU C CA  1 
ATOM   6243 C  C   . LEU C 1 206 ? -54.594 25.273  38.853  1   42.14  ? 202 LEU C C   1 
ATOM   6244 O  O   . LEU C 1 206 ? -55.399 25.972  39.458  1   42.35  ? 202 LEU C O   1 
ATOM   6245 C  CB  . LEU C 1 206 ? -54.867 24.631  36.417  1   39.49  ? 202 LEU C CB  1 
ATOM   6246 C  CG  . LEU C 1 206 ? -56.399 24.527  36.423  1   40.28  ? 202 LEU C CG  1 
ATOM   6247 C  CD1 . LEU C 1 206 ? -57.043 25.812  35.906  1   38.58  ? 202 LEU C CD1 1 
ATOM   6248 C  CD2 . LEU C 1 206 ? -56.857 23.296  35.614  1   39.24  ? 202 LEU C CD2 1 
ATOM   6249 N  N   . PHE C 1 207 ? -53.977 24.224  39.427  1   41.3   ? 203 PHE C N   1 
ATOM   6250 C  CA  . PHE C 1 207 ? -54.322 23.786  40.779  1   41.57  ? 203 PHE C CA  1 
ATOM   6251 C  C   . PHE C 1 207 ? -53.088 23.805  41.701  1   40.62  ? 203 PHE C C   1 
ATOM   6252 O  O   . PHE C 1 207 ? -52.561 22.752  42.099  1   40.58  ? 203 PHE C O   1 
ATOM   6253 C  CB  . PHE C 1 207 ? -55.018 22.427  40.651  1   40.44  ? 203 PHE C CB  1 
ATOM   6254 C  CG  . PHE C 1 207 ? -56.317 22.4    39.854  1   43.01  ? 203 PHE C CG  1 
ATOM   6255 C  CD1 . PHE C 1 207 ? -57.368 23.274  40.15   1   44.09  ? 203 PHE C CD1 1 
ATOM   6256 C  CD2 . PHE C 1 207 ? -56.486 21.495  38.803  1   42.73  ? 203 PHE C CD2 1 
ATOM   6257 C  CE1 . PHE C 1 207 ? -58.548 23.237  39.416  1   46.03  ? 203 PHE C CE1 1 
ATOM   6258 C  CE2 . PHE C 1 207 ? -57.678 21.446  38.088  1   44.83  ? 203 PHE C CE2 1 
ATOM   6259 C  CZ  . PHE C 1 207 ? -58.708 22.32   38.391  1   46.37  ? 203 PHE C CZ  1 
ATOM   6260 N  N   . PRO C 1 208 ? -52.578 24.999  42.075  1   38.86  ? 204 PRO C N   1 
ATOM   6261 C  CA  . PRO C 1 208 ? -51.38  25.089  42.912  1   38.58  ? 204 PRO C CA  1 
ATOM   6262 C  C   . PRO C 1 208 ? -51.601 24.849  44.405  1   39.12  ? 204 PRO C C   1 
ATOM   6263 O  O   . PRO C 1 208 ? -51.331 25.715  45.221  1   41.86  ? 204 PRO C O   1 
ATOM   6264 C  CB  . PRO C 1 208 ? -50.876 26.522  42.606  1   37.54  ? 204 PRO C CB  1 
ATOM   6265 C  CG  . PRO C 1 208 ? -52.142 27.304  42.408  1   39.21  ? 204 PRO C CG  1 
ATOM   6266 C  CD  . PRO C 1 208 ? -53.093 26.326  41.687  1   39.54  ? 204 PRO C CD  1 
ATOM   6267 N  N   . GLY C 1 209 ? -52.046 23.653  44.769  1   38.85  ? 205 GLY C N   1 
ATOM   6268 C  CA  . GLY C 1 209 ? -52.381 23.416  46.159  1   43.02  ? 205 GLY C CA  1 
ATOM   6269 C  C   . GLY C 1 209 ? -51.134 23.417  47.044  1   43.9   ? 205 GLY C C   1 
ATOM   6270 O  O   . GLY C 1 209 ? -50.04  23.142  46.554  1   43.58  ? 205 GLY C O   1 
ATOM   6271 N  N   . ASP C 1 210 ? -51.34  23.703  48.337  1   44.32  ? 206 ASP C N   1 
ATOM   6272 C  CA  . ASP C 1 210 ? -50.295 23.715  49.347  1   47.35  ? 206 ASP C CA  1 
ATOM   6273 C  C   . ASP C 1 210 ? -50.302 22.421  50.152  1   47.23  ? 206 ASP C C   1 
ATOM   6274 O  O   . ASP C 1 210 ? -49.446 22.224  50.997  1   49.08  ? 206 ASP C O   1 
ATOM   6275 C  CB  . ASP C 1 210 ? -50.564 24.738  50.437  1   49.94  ? 206 ASP C CB  1 
ATOM   6276 C  CG  . ASP C 1 210 ? -50.572 26.193  49.991  1   53.58  ? 206 ASP C CG  1 
ATOM   6277 O  OD1 . ASP C 1 210 ? -49.756 26.518  49.078  1   50.55  ? 206 ASP C OD1 1 
ATOM   6278 O  OD2 . ASP C 1 210 ? -51.391 26.978  50.568  1   54.96  ? 206 ASP C OD2 1 
ATOM   6279 N  N   . SER C 1 211 ? -51.31  21.581  49.952  1   47.91  ? 207 SER C N   1 
ATOM   6280 C  CA  . SER C 1 211 ? -51.501 20.361  50.727  1   48.92  ? 207 SER C CA  1 
ATOM   6281 C  C   . SER C 1 211 ? -52.541 19.532  49.998  1   48.88  ? 207 SER C C   1 
ATOM   6282 O  O   . SER C 1 211 ? -53.218 20.042  49.112  1   50.54  ? 207 SER C O   1 
ATOM   6283 C  CB  . SER C 1 211 ? -51.976 20.646  52.145  1   49.6   ? 207 SER C CB  1 
ATOM   6284 O  OG  . SER C 1 211 ? -53.288 21.203  52.162  1   50.17  ? 207 SER C OG  1 
ATOM   6285 N  N   . GLU C 1 212 ? -52.704 18.282  50.411  1   52.06  ? 208 GLU C N   1 
ATOM   6286 C  CA  . GLU C 1 212 ? -53.707 17.439  49.784  1   52.44  ? 208 GLU C CA  1 
ATOM   6287 C  C   . GLU C 1 212 ? -55.093 18.054  49.944  1   53     ? 208 GLU C C   1 
ATOM   6288 O  O   . GLU C 1 212 ? -55.857 18.074  48.964  1   52.45  ? 208 GLU C O   1 
ATOM   6289 C  CB  . GLU C 1 212 ? -53.614 16.048  50.389  1   53.66  ? 208 GLU C CB  1 
ATOM   6290 C  CG  . GLU C 1 212 ? -52.343 15.361  49.912  1   53.55  ? 208 GLU C CG  1 
ATOM   6291 C  CD  . GLU C 1 212 ? -52.226 13.973  50.488  1   57.75  ? 208 GLU C CD  1 
ATOM   6292 O  OE1 . GLU C 1 212 ? -53.211 13.474  51.079  1   57.08  ? 208 GLU C OE1 1 
ATOM   6293 O  OE2 . GLU C 1 212 ? -51.114 13.421  50.367  1   64.25  ? 208 GLU C OE2 1 
ATOM   6294 N  N   . ILE C 1 213 ? -55.383 18.548  51.168  1   49.41  ? 209 ILE C N   1 
ATOM   6295 C  CA  . ILE C 1 213 ? -56.654 19.195  51.453  1   48.81  ? 209 ILE C CA  1 
ATOM   6296 C  C   . ILE C 1 213 ? -56.872 20.326  50.443  1   48.24  ? 209 ILE C C   1 
ATOM   6297 O  O   . ILE C 1 213 ? -57.919 20.376  49.81   1   48.81  ? 209 ILE C O   1 
ATOM   6298 C  CB  . ILE C 1 213 ? -56.74  19.734  52.894  1   50.14  ? 209 ILE C CB  1 
ATOM   6299 C  CG1 . ILE C 1 213 ? -56.462 18.669  53.958  1   53.43  ? 209 ILE C CG1 1 
ATOM   6300 C  CG2 . ILE C 1 213 ? -58.086 20.419  53.128  1   49.51  ? 209 ILE C CG2 1 
ATOM   6301 C  CD1 . ILE C 1 213 ? -56.669 19.12   55.41   1   53.83  ? 209 ILE C CD1 1 
ATOM   6302 N  N   . ASP C 1 214 ? -55.898 21.251  50.342  1   46.75  ? 210 ASP C N   1 
ATOM   6303 C  CA  . ASP C 1 214 ? -55.986 22.456  49.534  1   44.83  ? 210 ASP C CA  1 
ATOM   6304 C  C   . ASP C 1 214 ? -56.101 22.06   48.063  1   43.6   ? 210 ASP C C   1 
ATOM   6305 O  O   . ASP C 1 214 ? -56.877 22.681  47.327  1   40.51  ? 210 ASP C O   1 
ATOM   6306 C  CB  . ASP C 1 214 ? -54.816 23.39   49.796  1   44.93  ? 210 ASP C CB  1 
ATOM   6307 C  CG  . ASP C 1 214 ? -54.845 24.721  49.058  1   45.03  ? 210 ASP C CG  1 
ATOM   6308 O  OD1 . ASP C 1 214 ? -55.822 25.47   49.257  1   46.71  ? 210 ASP C OD1 1 
ATOM   6309 O  OD2 . ASP C 1 214 ? -53.884 25.012  48.309  1   44.45  ? 210 ASP C OD2 1 
ATOM   6310 N  N   . GLN C 1 215 ? -55.325 21.057  47.647  1   41.77  ? 211 GLN C N   1 
ATOM   6311 C  CA  . GLN C 1 215 ? -55.355 20.613  46.23   1   42.8   ? 211 GLN C CA  1 
ATOM   6312 C  C   . GLN C 1 215 ? -56.78  20.164  45.878  1   45.89  ? 211 GLN C C   1 
ATOM   6313 O  O   . GLN C 1 215 ? -57.355 20.712  44.913  1   47.66  ? 211 GLN C O   1 
ATOM   6314 C  CB  . GLN C 1 215 ? -54.36  19.474  46.015  1   43.86  ? 211 GLN C CB  1 
ATOM   6315 C  CG  . GLN C 1 215 ? -54.257 19.011  44.567  1   41.86  ? 211 GLN C CG  1 
ATOM   6316 C  CD  . GLN C 1 215 ? -53.416 19.926  43.707  1   41.15  ? 211 GLN C CD  1 
ATOM   6317 O  OE1 . GLN C 1 215 ? -52.504 20.609  44.187  1   42.76  ? 211 GLN C OE1 1 
ATOM   6318 N  NE2 . GLN C 1 215 ? -53.713 19.94   42.417  1   38.2   ? 211 GLN C NE2 1 
ATOM   6319 N  N   . LEU C 1 216 ? -57.328 19.214  46.641  1   47.41  ? 212 LEU C N   1 
ATOM   6320 C  CA  . LEU C 1 216 ? -58.686 18.682  46.356  1   48.82  ? 212 LEU C CA  1 
ATOM   6321 C  C   . LEU C 1 216 ? -59.698 19.835  46.294  1   50.69  ? 212 LEU C C   1 
ATOM   6322 O  O   . LEU C 1 216 ? -60.513 19.856  45.353  1   55.26  ? 212 LEU C O   1 
ATOM   6323 C  CB  . LEU C 1 216 ? -59.062 17.674  47.438  1   51.2   ? 212 LEU C CB  1 
ATOM   6324 C  CG  . LEU C 1 216 ? -58.646 16.227  47.16   1   54.7   ? 212 LEU C CG  1 
ATOM   6325 C  CD1 . LEU C 1 216 ? -58.596 15.411  48.438  1   53.55  ? 212 LEU C CD1 1 
ATOM   6326 C  CD2 . LEU C 1 216 ? -59.574 15.593  46.139  1   57.7   ? 212 LEU C CD2 1 
ATOM   6327 N  N   . PHE C 1 217 ? -59.654 20.744  47.269  1   50.61  ? 213 PHE C N   1 
ATOM   6328 C  CA  . PHE C 1 217 ? -60.642 21.854  47.318  1   48.07  ? 213 PHE C CA  1 
ATOM   6329 C  C   . PHE C 1 217 ? -60.507 22.693  46.054  1   48.86  ? 213 PHE C C   1 
ATOM   6330 O  O   . PHE C 1 217 ? -61.534 23.027  45.426  1   53.24  ? 213 PHE C O   1 
ATOM   6331 C  CB  . PHE C 1 217 ? -60.398 22.672  48.589  1   46.92  ? 213 PHE C CB  1 
ATOM   6332 C  CG  . PHE C 1 217 ? -60.868 21.998  49.871  1   47.52  ? 213 PHE C CG  1 
ATOM   6333 C  CD1 . PHE C 1 217 ? -61.396 20.712  49.851  1   46.68  ? 213 PHE C CD1 1 
ATOM   6334 C  CD2 . PHE C 1 217 ? -60.785 22.653  51.093  1   48.09  ? 213 PHE C CD2 1 
ATOM   6335 C  CE1 . PHE C 1 217 ? -61.823 20.101  51.017  1   47.08  ? 213 PHE C CE1 1 
ATOM   6336 C  CE2 . PHE C 1 217 ? -61.218 22.038  52.257  1   48.47  ? 213 PHE C CE2 1 
ATOM   6337 C  CZ  . PHE C 1 217 ? -61.735 20.765  52.217  1   48.31  ? 213 PHE C CZ  1 
ATOM   6338 N  N   . ARG C 1 218 ? -59.269 23.026  45.685  1   47.89  ? 214 ARG C N   1 
ATOM   6339 C  CA  . ARG C 1 218 ? -59.029 23.846  44.501  1   48.12  ? 214 ARG C CA  1 
ATOM   6340 C  C   . ARG C 1 218 ? -59.68  23.229  43.256  1   52.09  ? 214 ARG C C   1 
ATOM   6341 O  O   . ARG C 1 218 ? -60.125 23.954  42.353  1   51.46  ? 214 ARG C O   1 
ATOM   6342 C  CB  . ARG C 1 218 ? -57.533 24.032  44.255  1   43.17  ? 214 ARG C CB  1 
ATOM   6343 C  CG  . ARG C 1 218 ? -56.959 25.124  45.144  1   41.42  ? 214 ARG C CG  1 
ATOM   6344 C  CD  . ARG C 1 218 ? -55.45  25.103  44.993  1   39.35  ? 214 ARG C CD  1 
ATOM   6345 N  NE  . ARG C 1 218 ? -54.809 26.071  45.876  1   40.54  ? 214 ARG C NE  1 
ATOM   6346 C  CZ  . ARG C 1 218 ? -54.762 27.337  45.505  1   42.43  ? 214 ARG C CZ  1 
ATOM   6347 N  NH1 . ARG C 1 218 ? -55.237 27.658  44.309  1   41.14  ? 214 ARG C NH1 1 
ATOM   6348 N  NH2 . ARG C 1 218 ? -54.255 28.253  46.324  1   43.35  ? 214 ARG C NH2 1 
ATOM   6349 N  N   . ILE C 1 219 ? -59.73  21.891  43.238  1   51.15  ? 215 ILE C N   1 
ATOM   6350 C  CA  . ILE C 1 219 ? -60.436 21.13   42.226  1   55.83  ? 215 ILE C CA  1 
ATOM   6351 C  C   . ILE C 1 219 ? -61.953 21.211  42.457  1   63.26  ? 215 ILE C C   1 
ATOM   6352 O  O   . ILE C 1 219 ? -62.699 21.61   41.551  1   68.4   ? 215 ILE C O   1 
ATOM   6353 C  CB  . ILE C 1 219 ? -59.904 19.685  42.191  1   54.32  ? 215 ILE C CB  1 
ATOM   6354 C  CG1 . ILE C 1 219 ? -58.388 19.66   41.903  1   49.14  ? 215 ILE C CG1 1 
ATOM   6355 C  CG2 . ILE C 1 219 ? -60.691 18.822  41.2    1   54.46  ? 215 ILE C CG2 1 
ATOM   6356 C  CD1 . ILE C 1 219 ? -57.717 18.34   42.23   1   46.22  ? 215 ILE C CD1 1 
ATOM   6357 N  N   . PHE C 1 220 ? -62.396 20.843  43.673  1   62.97  ? 216 PHE C N   1 
ATOM   6358 C  CA  . PHE C 1 220 ? -63.805 20.777  44.036  1   64.06  ? 216 PHE C CA  1 
ATOM   6359 C  C   . PHE C 1 220 ? -64.547 22.049  43.642  1   66.71  ? 216 PHE C C   1 
ATOM   6360 O  O   . PHE C 1 220 ? -65.733 21.986  43.326  1   81.17  ? 216 PHE C O   1 
ATOM   6361 C  CB  . PHE C 1 220 ? -64.075 20.713  45.539  1   63.35  ? 216 PHE C CB  1 
ATOM   6362 C  CG  . PHE C 1 220 ? -63.716 19.415  46.246  1   65.06  ? 216 PHE C CG  1 
ATOM   6363 C  CD1 . PHE C 1 220 ? -63.349 18.273  45.528  1   64.02  ? 216 PHE C CD1 1 
ATOM   6364 C  CD2 . PHE C 1 220 ? -63.79  19.334  47.639  1   66.31  ? 216 PHE C CD2 1 
ATOM   6365 C  CE1 . PHE C 1 220 ? -63.021 17.097  46.197  1   68.05  ? 216 PHE C CE1 1 
ATOM   6366 C  CE2 . PHE C 1 220 ? -63.478 18.154  48.308  1   71.42  ? 216 PHE C CE2 1 
ATOM   6367 C  CZ  . PHE C 1 220 ? -63.084 17.039  47.583  1   71.91  ? 216 PHE C CZ  1 
ATOM   6368 N  N   . ARG C 1 221 ? -63.877 23.203  43.692  1   62.75  ? 217 ARG C N   1 
ATOM   6369 C  CA  . ARG C 1 221 ? -64.586 24.459  43.496  1   66.65  ? 217 ARG C CA  1 
ATOM   6370 C  C   . ARG C 1 221 ? -64.911 24.655  42.019  1   72.34  ? 217 ARG C C   1 
ATOM   6371 O  O   . ARG C 1 221 ? -65.799 25.436  41.67   1   76.58  ? 217 ARG C O   1 
ATOM   6372 C  CB  . ARG C 1 221 ? -63.886 25.674  44.113  1   61.26  ? 217 ARG C CB  1 
ATOM   6373 C  CG  . ARG C 1 221 ? -62.541 26.027  43.511  1   55.54  ? 217 ARG C CG  1 
ATOM   6374 C  CD  . ARG C 1 221 ? -62.022 27.191  44.291  1   54.61  ? 217 ARG C CD  1 
ATOM   6375 N  NE  . ARG C 1 221 ? -60.637 27.51   43.932  1   55.18  ? 217 ARG C NE  1 
ATOM   6376 C  CZ  . ARG C 1 221 ? -60.001 28.586  44.41   1   57.48  ? 217 ARG C CZ  1 
ATOM   6377 N  NH1 . ARG C 1 221 ? -60.592 29.309  45.362  1   59.8   ? 217 ARG C NH1 1 
ATOM   6378 N  NH2 . ARG C 1 221 ? -58.792 28.925  43.956  1   51.48  ? 217 ARG C NH2 1 
ATOM   6379 N  N   . THR C 1 222 ? -64.201 23.92   41.158  1   77.39  ? 218 THR C N   1 
ATOM   6380 C  CA  . THR C 1 222 ? -64.565 23.874  39.749  1   75.2   ? 218 THR C CA  1 
ATOM   6381 C  C   . THR C 1 222 ? -65.682 22.84   39.519  1   74.01  ? 218 THR C C   1 
ATOM   6382 O  O   . THR C 1 222 ? -66.28  22.787  38.449  1   73.55  ? 218 THR C O   1 
ATOM   6383 C  CB  . THR C 1 222 ? -63.297 23.666  38.928  1   69.22  ? 218 THR C CB  1 
ATOM   6384 O  OG1 . THR C 1 222 ? -63.055 22.272  39.103  1   68.91  ? 218 THR C OG1 1 
ATOM   6385 C  CG2 . THR C 1 222 ? -62.171 24.568  39.417  1   63.53  ? 218 THR C CG2 1 
ATOM   6386 N  N   . LEU C 1 223 ? -66.043 22.096  40.572  1   72.46  ? 219 LEU C N   1 
ATOM   6387 C  CA  . LEU C 1 223 ? -67.037 21.041  40.478  1   73.69  ? 219 LEU C CA  1 
ATOM   6388 C  C   . LEU C 1 223 ? -68.447 21.606  40.466  1   78.06  ? 219 LEU C C   1 
ATOM   6389 O  O   . LEU C 1 223 ? -69.353 20.91   40.014  1   80.99  ? 219 LEU C O   1 
ATOM   6390 C  CB  . LEU C 1 223 ? -66.884 19.987  41.573  1   75.96  ? 219 LEU C CB  1 
ATOM   6391 C  CG  . LEU C 1 223 ? -66.201 18.681  41.15   1   76.44  ? 219 LEU C CG  1 
ATOM   6392 C  CD1 . LEU C 1 223 ? -64.823 18.876  40.521  1   71.15  ? 219 LEU C CD1 1 
ATOM   6393 C  CD2 . LEU C 1 223 ? -66.169 17.676  42.301  1   76.29  ? 219 LEU C CD2 1 
ATOM   6394 N  N   . GLY C 1 224 ? -68.623 22.834  40.976  1   83.23  ? 220 GLY C N   1 
ATOM   6395 C  CA  . GLY C 1 224 ? -69.938 23.46   41.105  1   90.42  ? 220 GLY C CA  1 
ATOM   6396 C  C   . GLY C 1 224 ? -70.577 23.163  42.465  1   96.28  ? 220 GLY C C   1 
ATOM   6397 O  O   . GLY C 1 224 ? -69.855 23.015  43.453  1   105.21 ? 220 GLY C O   1 
ATOM   6398 N  N   . THR C 1 225 ? -71.919 23.044  42.5    1   94.75  ? 221 THR C N   1 
ATOM   6399 C  CA  . THR C 1 225 ? -72.665 22.783  43.731  1   91.55  ? 221 THR C CA  1 
ATOM   6400 C  C   . THR C 1 225 ? -73.337 21.414  43.646  1   88.73  ? 221 THR C C   1 
ATOM   6401 O  O   . THR C 1 225 ? -73.303 20.662  44.662  1   84.49  ? 221 THR C O   1 
ATOM   6402 C  CB  . THR C 1 225 ? -73.63  23.93   44.095  1   91.24  ? 221 THR C CB  1 
ATOM   6403 O  OG1 . THR C 1 225 ? -74.828 23.902  43.317  1   91.47  ? 221 THR C OG1 1 
ATOM   6404 C  CG2 . THR C 1 225 ? -72.992 25.311  44.058  1   87.91  ? 221 THR C CG2 1 
ATOM   6405 N  N   . VAL C 1 230 ? -72.925 14.498  47.5    1   79     ? 226 VAL C N   1 
ATOM   6406 C  CA  . VAL C 1 230 ? -73.022 15.731  48.346  1   84.9   ? 226 VAL C CA  1 
ATOM   6407 C  C   . VAL C 1 230 ? -71.619 16.198  48.759  1   84.84  ? 226 VAL C C   1 
ATOM   6408 O  O   . VAL C 1 230 ? -71.207 17.319  48.451  1   83.19  ? 226 VAL C O   1 
ATOM   6409 C  CB  . VAL C 1 230 ? -73.972 15.546  49.553  1   87.67  ? 226 VAL C CB  1 
ATOM   6410 C  CG1 . VAL C 1 230 ? -73.768 14.198  50.254  1   88.48  ? 226 VAL C CG1 1 
ATOM   6411 C  CG2 . VAL C 1 230 ? -73.901 16.717  50.533  1   84.51  ? 226 VAL C CG2 1 
ATOM   6412 N  N   . TRP C 1 231 ? -70.914 15.348  49.515  1   83.12  ? 227 TRP C N   1 
ATOM   6413 C  CA  . TRP C 1 231 ? -69.489 15.522  49.722  1   80.3   ? 227 TRP C CA  1 
ATOM   6414 C  C   . TRP C 1 231 ? -68.716 14.727  48.655  1   82.48  ? 227 TRP C C   1 
ATOM   6415 O  O   . TRP C 1 231 ? -68.774 13.491  48.611  1   80.49  ? 227 TRP C O   1 
ATOM   6416 C  CB  . TRP C 1 231 ? -69.061 15.187  51.166  1   78.44  ? 227 TRP C CB  1 
ATOM   6417 C  CG  . TRP C 1 231 ? -67.658 15.666  51.445  1   74.36  ? 227 TRP C CG  1 
ATOM   6418 C  CD1 . TRP C 1 231 ? -66.516 14.921  51.539  1   70.16  ? 227 TRP C CD1 1 
ATOM   6419 C  CD2 . TRP C 1 231 ? -67.251 17.053  51.56   1   72.86  ? 227 TRP C CD2 1 
ATOM   6420 N  NE1 . TRP C 1 231 ? -65.432 15.742  51.726  1   69.02  ? 227 TRP C NE1 1 
ATOM   6421 C  CE2 . TRP C 1 231 ? -65.849 17.053  51.739  1   68.87  ? 227 TRP C CE2 1 
ATOM   6422 C  CE3 . TRP C 1 231 ? -67.938 18.277  51.543  1   72.56  ? 227 TRP C CE3 1 
ATOM   6423 C  CZ2 . TRP C 1 231 ? -65.128 18.234  51.891  1   65.44  ? 227 TRP C CZ2 1 
ATOM   6424 C  CZ3 . TRP C 1 231 ? -67.223 19.441  51.703  1   69.09  ? 227 TRP C CZ3 1 
ATOM   6425 C  CH2 . TRP C 1 231 ? -65.839 19.412  51.855  1   66.31  ? 227 TRP C CH2 1 
ATOM   6426 N  N   . PRO C 1 232 ? -68.006 15.418  47.721  1   81.18  ? 228 PRO C N   1 
ATOM   6427 C  CA  . PRO C 1 232 ? -67.198 14.744  46.7    1   79.44  ? 228 PRO C CA  1 
ATOM   6428 C  C   . PRO C 1 232 ? -65.917 14.026  47.139  1   78.38  ? 228 PRO C C   1 
ATOM   6429 O  O   . PRO C 1 232 ? -65.352 13.269  46.348  1   74.09  ? 228 PRO C O   1 
ATOM   6430 C  CB  . PRO C 1 232 ? -66.922 15.854  45.652  1   77.41  ? 228 PRO C CB  1 
ATOM   6431 C  CG  . PRO C 1 232 ? -67.014 17.148  46.431  1   74.56  ? 228 PRO C CG  1 
ATOM   6432 C  CD  . PRO C 1 232 ? -67.99  16.887  47.57   1   78.99  ? 228 PRO C CD  1 
ATOM   6433 N  N   . GLY C 1 233 ? -65.481 14.259  48.391  1   76.85  ? 229 GLY C N   1 
ATOM   6434 C  CA  . GLY C 1 233 ? -64.284 13.65   48.957  1   75.45  ? 229 GLY C CA  1 
ATOM   6435 C  C   . GLY C 1 233 ? -64.515 12.216  49.449  1   80.43  ? 229 GLY C C   1 
ATOM   6436 O  O   . GLY C 1 233 ? -64.133 11.879  50.567  1   79.43  ? 229 GLY C O   1 
ATOM   6437 N  N   . VAL C 1 234 ? -65.125 11.377  48.594  1   82.72  ? 230 VAL C N   1 
ATOM   6438 C  CA  . VAL C 1 234 ? -65.34  9.955   48.829  1   82.35  ? 230 VAL C CA  1 
ATOM   6439 C  C   . VAL C 1 234 ? -64.68  9.188   47.69   1   84.59  ? 230 VAL C C   1 
ATOM   6440 O  O   . VAL C 1 234 ? -64.76  9.62    46.539  1   81.89  ? 230 VAL C O   1 
ATOM   6441 C  CB  . VAL C 1 234 ? -66.833 9.578   48.91   1   86.37  ? 230 VAL C CB  1 
ATOM   6442 C  CG1 . VAL C 1 234 ? -67.455 9.985   50.238  1   90.07  ? 230 VAL C CG1 1 
ATOM   6443 C  CG2 . VAL C 1 234 ? -67.635 10.111  47.722  1   86.44  ? 230 VAL C CG2 1 
ATOM   6444 N  N   . THR C 1 235 ? -64.073 8.034   48.017  1   88.52  ? 231 THR C N   1 
ATOM   6445 C  CA  . THR C 1 235 ? -63.364 7.223   47.033  1   89.57  ? 231 THR C CA  1 
ATOM   6446 C  C   . THR C 1 235 ? -64.285 6.812   45.874  1   94.4   ? 231 THR C C   1 
ATOM   6447 O  O   . THR C 1 235 ? -63.768 6.42    44.828  1   94.95  ? 231 THR C O   1 
ATOM   6448 C  CB  . THR C 1 235 ? -62.645 6.026   47.671  1   89.23  ? 231 THR C CB  1 
ATOM   6449 O  OG1 . THR C 1 235 ? -63.58  5.289   48.458  1   96.48  ? 231 THR C OG1 1 
ATOM   6450 C  CG2 . THR C 1 235 ? -61.501 6.425   48.584  1   84.74  ? 231 THR C CG2 1 
ATOM   6451 N  N   . SER C 1 236 ? -65.626 6.916   46.052  1   97.26  ? 232 SER C N   1 
ATOM   6452 C  CA  . SER C 1 236 ? -66.622 6.421   45.098  1   96.34  ? 232 SER C CA  1 
ATOM   6453 C  C   . SER C 1 236 ? -66.607 7.21    43.785  1   101.03 ? 232 SER C C   1 
ATOM   6454 O  O   . SER C 1 236 ? -66.979 6.669   42.745  1   100.53 ? 232 SER C O   1 
ATOM   6455 C  CB  . SER C 1 236 ? -68.031 6.264   45.686  1   88.63  ? 232 SER C CB  1 
ATOM   6456 O  OG  . SER C 1 236 ? -68.494 7.417   46.374  1   81.6   ? 232 SER C OG  1 
ATOM   6457 N  N   . MET C 1 237 ? -66.152 8.472   43.846  1   107.59 ? 233 MET C N   1 
ATOM   6458 C  CA  . MET C 1 237 ? -65.888 9.328   42.69   1   111.48 ? 233 MET C CA  1 
ATOM   6459 C  C   . MET C 1 237 ? -67.197 9.681   41.989  1   112.46 ? 233 MET C C   1 
ATOM   6460 O  O   . MET C 1 237 ? -67.449 9.223   40.871  1   117.09 ? 233 MET C O   1 
ATOM   6461 C  CB  . MET C 1 237 ? -64.909 8.701   41.683  1   112.79 ? 233 MET C CB  1 
ATOM   6462 C  CG  . MET C 1 237 ? -63.534 8.353   42.237  1   106.14 ? 233 MET C CG  1 
ATOM   6463 S  SD  . MET C 1 237 ? -62.633 9.742   42.957  1   94.31  ? 233 MET C SD  1 
ATOM   6464 C  CE  . MET C 1 237 ? -62.65  10.865  41.551  1   99.04  ? 233 MET C CE  1 
ATOM   6465 N  N   . PRO C 1 238 ? -68.056 10.52   42.614  1   108.68 ? 234 PRO C N   1 
ATOM   6466 C  CA  . PRO C 1 238 ? -69.334 10.88   41.999  1   112.23 ? 234 PRO C CA  1 
ATOM   6467 C  C   . PRO C 1 238 ? -69.104 11.659  40.699  1   111.27 ? 234 PRO C C   1 
ATOM   6468 O  O   . PRO C 1 238 ? -68.12  12.384  40.564  1   110.47 ? 234 PRO C O   1 
ATOM   6469 C  CB  . PRO C 1 238 ? -70.062 11.684  43.105  1   109.92 ? 234 PRO C CB  1 
ATOM   6470 C  CG  . PRO C 1 238 ? -68.945 12.206  43.993  1   103.34 ? 234 PRO C CG  1 
ATOM   6471 C  CD  . PRO C 1 238 ? -67.823 11.188  43.909  1   100.43 ? 234 PRO C CD  1 
ATOM   6472 N  N   . ASP C 1 239 ? -70.015 11.475  39.738  1   111.28 ? 235 ASP C N   1 
ATOM   6473 C  CA  . ASP C 1 239 ? -69.963 12.128  38.436  1   109.25 ? 235 ASP C CA  1 
ATOM   6474 C  C   . ASP C 1 239 ? -70.23  13.64   38.546  1   105.95 ? 235 ASP C C   1 
ATOM   6475 O  O   . ASP C 1 239 ? -71.368 14.075  38.766  1   98.95  ? 235 ASP C O   1 
ATOM   6476 C  CB  . ASP C 1 239 ? -70.819 11.352  37.445  1   112.45 ? 235 ASP C CB  1 
ATOM   6477 C  CG  . ASP C 1 239 ? -71.333 12.129  36.243  1   110.36 ? 235 ASP C CG  1 
ATOM   6478 O  OD1 . ASP C 1 239 ? -70.488 12.614  35.456  1   99.63  ? 235 ASP C OD1 1 
ATOM   6479 O  OD2 . ASP C 1 239 ? -72.578 12.24   36.112  1   112.78 ? 235 ASP C OD2 1 
ATOM   6480 N  N   . TYR C 1 240 ? -69.149 14.426  38.37   1   103.52 ? 236 TYR C N   1 
ATOM   6481 C  CA  . TYR C 1 240 ? -69.11  15.887  38.398  1   100.16 ? 236 TYR C CA  1 
ATOM   6482 C  C   . TYR C 1 240 ? -68.149 16.422  37.318  1   100.64 ? 236 TYR C C   1 
ATOM   6483 O  O   . TYR C 1 240 ? -66.926 16.428  37.496  1   93.7   ? 236 TYR C O   1 
ATOM   6484 C  CB  . TYR C 1 240 ? -68.673 16.413  39.778  1   93.34  ? 236 TYR C CB  1 
ATOM   6485 C  CG  . TYR C 1 240 ? -69.692 16.42   40.911  1   88.72  ? 236 TYR C CG  1 
ATOM   6486 C  CD1 . TYR C 1 240 ? -70.734 17.344  40.938  1   90.75  ? 236 TYR C CD1 1 
ATOM   6487 C  CD2 . TYR C 1 240 ? -69.599 15.519  41.973  1   87.46  ? 236 TYR C CD2 1 
ATOM   6488 C  CE1 . TYR C 1 240 ? -71.673 17.339  41.963  1   91.6   ? 236 TYR C CE1 1 
ATOM   6489 C  CE2 . TYR C 1 240 ? -70.528 15.504  43.003  1   85.34  ? 236 TYR C CE2 1 
ATOM   6490 C  CZ  . TYR C 1 240 ? -71.569 16.418  42.997  1   89.02  ? 236 TYR C CZ  1 
ATOM   6491 O  OH  . TYR C 1 240 ? -72.464 16.404  44.027  1   85.53  ? 236 TYR C OH  1 
ATOM   6492 N  N   . LYS C 1 241 ? -68.702 16.908  36.195  1   101.28 ? 237 LYS C N   1 
ATOM   6493 C  CA  . LYS C 1 241 ? -67.905 17.543  35.151  1   101.19 ? 237 LYS C CA  1 
ATOM   6494 C  C   . LYS C 1 241 ? -67.648 19.001  35.546  1   102.66 ? 237 LYS C C   1 
ATOM   6495 O  O   . LYS C 1 241 ? -68.588 19.715  35.901  1   102.6  ? 237 LYS C O   1 
ATOM   6496 C  CB  . LYS C 1 241 ? -68.614 17.448  33.79   1   99.29  ? 237 LYS C CB  1 
ATOM   6497 C  CG  . LYS C 1 241 ? -67.785 17.792  32.548  1   96.04  ? 237 LYS C CG  1 
ATOM   6498 C  CD  . LYS C 1 241 ? -68.522 18.395  31.351  1   98.61  ? 237 LYS C CD  1 
ATOM   6499 C  CE  . LYS C 1 241 ? -69.781 17.736  30.852  1   102.74 ? 237 LYS C CE  1 
ATOM   6500 N  NZ  . LYS C 1 241 ? -69.574 16.422  30.237  1   102.26 ? 237 LYS C NZ  1 
ATOM   6501 N  N   . PRO C 1 242 ? -66.379 19.49   35.54   1   99.68  ? 238 PRO C N   1 
ATOM   6502 C  CA  . PRO C 1 242 ? -66.101 20.906  35.817  1   99.71  ? 238 PRO C CA  1 
ATOM   6503 C  C   . PRO C 1 242 ? -66.247 21.919  34.673  1   98.09  ? 238 PRO C C   1 
ATOM   6504 O  O   . PRO C 1 242 ? -66.341 21.564  33.494  1   95.76  ? 238 PRO C O   1 
ATOM   6505 C  CB  . PRO C 1 242 ? -64.672 20.906  36.45   1   94.33  ? 238 PRO C CB  1 
ATOM   6506 C  CG  . PRO C 1 242 ? -64.048 19.611  35.961  1   95.63  ? 238 PRO C CG  1 
ATOM   6507 C  CD  . PRO C 1 242 ? -65.147 18.699  35.379  1   93.67  ? 238 PRO C CD  1 
ATOM   6508 N  N   . SER C 1 243 ? -66.256 23.199  35.065  1   95.38  ? 239 SER C N   1 
ATOM   6509 C  CA  . SER C 1 243 ? -66.359 24.351  34.183  1   92.72  ? 239 SER C CA  1 
ATOM   6510 C  C   . SER C 1 243 ? -65.555 25.516  34.792  1   91.39  ? 239 SER C C   1 
ATOM   6511 O  O   . SER C 1 243 ? -65.414 26.559  34.109  1   94.31  ? 239 SER C O   1 
ATOM   6512 C  CB  . SER C 1 243 ? -67.805 24.717  34.005  1   86.1   ? 239 SER C CB  1 
ATOM   6513 O  OG  . SER C 1 243 ? -68.417 24.745  35.286  1   77.76  ? 239 SER C OG  1 
ATOM   6514 N  N   . PRO C 1 257 ? -59.042 31.527  29.495  1   110.97 ? 253 PRO C N   1 
ATOM   6515 C  CA  . PRO C 1 257 ? -59.563 32.849  29.144  1   108.55 ? 253 PRO C CA  1 
ATOM   6516 C  C   . PRO C 1 257 ? -59.485 33.402  27.707  1   108.4  ? 253 PRO C C   1 
ATOM   6517 O  O   . PRO C 1 257 ? -60.523 33.766  27.152  1   114.8  ? 253 PRO C O   1 
ATOM   6518 C  CB  . PRO C 1 257 ? -58.986 33.759  30.256  1   102.83 ? 253 PRO C CB  1 
ATOM   6519 C  CG  . PRO C 1 257 ? -59.101 32.86   31.481  1   106.36 ? 253 PRO C CG  1 
ATOM   6520 C  CD  . PRO C 1 257 ? -58.999 31.409  30.966  1   109.9  ? 253 PRO C CD  1 
ATOM   6521 N  N   . PRO C 1 258 ? -58.316 33.505  27.017  1   102.8  ? 254 PRO C N   1 
ATOM   6522 C  CA  . PRO C 1 258 ? -58.342 33.668  25.556  1   98.43  ? 254 PRO C CA  1 
ATOM   6523 C  C   . PRO C 1 258 ? -58.532 32.309  24.88   1   96.69  ? 254 PRO C C   1 
ATOM   6524 O  O   . PRO C 1 258 ? -57.761 31.923  24.001  1   96.99  ? 254 PRO C O   1 
ATOM   6525 C  CB  . PRO C 1 258 ? -56.971 34.301  25.247  1   96.25  ? 254 PRO C CB  1 
ATOM   6526 C  CG  . PRO C 1 258 ? -56.055 33.769  26.341  1   89.42  ? 254 PRO C CG  1 
ATOM   6527 C  CD  . PRO C 1 258 ? -56.946 33.567  27.57   1   93.21  ? 254 PRO C CD  1 
ATOM   6528 N  N   . LEU C 1 259 ? -59.503 31.542  25.384  1   89.23  ? 255 LEU C N   1 
ATOM   6529 C  CA  . LEU C 1 259 ? -59.701 30.162  24.876  1   85.06  ? 255 LEU C CA  1 
ATOM   6530 C  C   . LEU C 1 259 ? -61.121 29.973  24.33   1   88.65  ? 255 LEU C C   1 
ATOM   6531 O  O   . LEU C 1 259 ? -62.078 30.277  25.063  1   83.54  ? 255 LEU C O   1 
ATOM   6532 C  CB  . LEU C 1 259 ? -59.422 29.184  26.014  1   76.48  ? 255 LEU C CB  1 
ATOM   6533 C  CG  . LEU C 1 259 ? -59.196 27.727  25.604  1   74.61  ? 255 LEU C CG  1 
ATOM   6534 C  CD1 . LEU C 1 259 ? -57.969 27.613  24.721  1   68.82  ? 255 LEU C CD1 1 
ATOM   6535 C  CD2 . LEU C 1 259 ? -59.059 26.842  26.826  1   73.34  ? 255 LEU C CD2 1 
ATOM   6536 N  N   . ASP C 1 260 ? -61.265 29.463  23.136  1   89.53  ? 256 ASP C N   1 
ATOM   6537 C  CA  . ASP C 1 260 ? -62.59  29.231  22.509  1   92.81  ? 256 ASP C CA  1 
ATOM   6538 C  C   . ASP C 1 260 ? -63.345 28.112  23.22   1   91.95  ? 256 ASP C C   1 
ATOM   6539 O  O   . ASP C 1 260 ? -62.766 27.464  24.108  1   84.62  ? 256 ASP C O   1 
ATOM   6540 C  CB  . ASP C 1 260 ? -62.418 28.816  21.063  1   99.82  ? 256 ASP C CB  1 
ATOM   6541 C  CG  . ASP C 1 260 ? -61.637 27.526  20.856  1   105.15 ? 256 ASP C CG  1 
ATOM   6542 O  OD1 . ASP C 1 260 ? -61.148 26.97   21.857  1   107.77 ? 256 ASP C OD1 1 
ATOM   6543 O  OD2 . ASP C 1 260 ? -61.513 27.096  19.692  1   100.2  ? 256 ASP C OD2 1 
ATOM   6544 N  N   . GLU C 1 261 ? -64.561 27.836  22.784  1   93.53  ? 257 GLU C N   1 
ATOM   6545 C  CA  . GLU C 1 261 ? -65.423 26.848  23.482  1   89.37  ? 257 GLU C CA  1 
ATOM   6546 C  C   . GLU C 1 261 ? -64.95  25.44   23.133  1   81.77  ? 257 GLU C C   1 
ATOM   6547 O  O   . GLU C 1 261 ? -65.212 24.518  23.916  1   76.11  ? 257 GLU C O   1 
ATOM   6548 C  CB  . GLU C 1 261 ? -66.889 27.015  23.086  1   91.86  ? 257 GLU C CB  1 
ATOM   6549 C  CG  . GLU C 1 261 ? -67.156 26.815  21.599  1   92.5   ? 257 GLU C CG  1 
ATOM   6550 C  CD  . GLU C 1 261 ? -68.624 26.556  21.325  1   99.4   ? 257 GLU C CD  1 
ATOM   6551 O  OE1 . GLU C 1 261 ? -69.091 26.891  20.218  1   101.48 ? 257 GLU C OE1 1 
ATOM   6552 O  OE2 . GLU C 1 261 ? -69.301 26.026  22.229  1   100.03 ? 257 GLU C OE2 1 
ATOM   6553 N  N   . ASP C 1 262 ? -64.282 25.308  21.993  1   77.54  ? 258 ASP C N   1 
ATOM   6554 C  CA  . ASP C 1 262 ? -63.728 23.991  21.608  1   73.53  ? 258 ASP C CA  1 
ATOM   6555 C  C   . ASP C 1 262 ? -62.682 23.631  22.662  1   70.34  ? 258 ASP C C   1 
ATOM   6556 O  O   . ASP C 1 262 ? -62.837 22.589  23.321  1   67.97  ? 258 ASP C O   1 
ATOM   6557 C  CB  . ASP C 1 262 ? -63.216 24.039  20.178  1   73.29  ? 258 ASP C CB  1 
ATOM   6558 C  CG  . ASP C 1 262 ? -64.243 23.707  19.107  1   76.02  ? 258 ASP C CG  1 
ATOM   6559 O  OD1 . ASP C 1 262 ? -65.315 23.181  19.469  1   74.13  ? 258 ASP C OD1 1 
ATOM   6560 O  OD2 . ASP C 1 262 ? -63.96  23.978  17.924  1   76.88  ? 258 ASP C OD2 1 
ATOM   6561 N  N   . GLY C 1 263 ? -61.691 24.503  22.835  1   67.61  ? 259 GLY C N   1 
ATOM   6562 C  CA  . GLY C 1 263 ? -60.651 24.266  23.845  1   62.44  ? 259 GLY C CA  1 
ATOM   6563 C  C   . GLY C 1 263 ? -61.275 24.123  25.202  1   60.59  ? 259 GLY C C   1 
ATOM   6564 O  O   . GLY C 1 263 ? -60.823 23.269  25.972  1   60.07  ? 259 GLY C O   1 
ATOM   6565 N  N   . ARG C 1 264 ? -62.29  24.926  25.477  1   61.61  ? 260 ARG C N   1 
ATOM   6566 C  CA  . ARG C 1 264 ? -62.898 24.902  26.823  1   65.65  ? 260 ARG C CA  1 
ATOM   6567 C  C   . ARG C 1 264 ? -63.613 23.564  27.01   1   67.05  ? 260 ARG C C   1 
ATOM   6568 O  O   . ARG C 1 264 ? -63.565 23.025  28.127  1   69.31  ? 260 ARG C O   1 
ATOM   6569 C  CB  . ARG C 1 264 ? -63.818 26.111  27.014  1   73     ? 260 ARG C CB  1 
ATOM   6570 C  CG  . ARG C 1 264 ? -63.054 27.344  27.474  1   77.31  ? 260 ARG C CG  1 
ATOM   6571 C  CD  . ARG C 1 264 ? -63.957 28.542  27.695  1   85.72  ? 260 ARG C CD  1 
ATOM   6572 N  NE  . ARG C 1 264 ? -64.172 29.307  26.463  1   95.8   ? 260 ARG C NE  1 
ATOM   6573 C  CZ  . ARG C 1 264 ? -65.355 29.481  25.89   1   98.51  ? 260 ARG C CZ  1 
ATOM   6574 N  NH1 . ARG C 1 264 ? -66.396 28.781  26.303  1   95.56  ? 260 ARG C NH1 1 
ATOM   6575 N  NH2 . ARG C 1 264 ? -65.492 30.349  24.903  1   95.76  ? 260 ARG C NH2 1 
ATOM   6576 N  N   . SER C 1 265 ? -64.246 23.046  25.962  1   67.51  ? 261 SER C N   1 
ATOM   6577 C  CA  . SER C 1 265 ? -64.85  21.736  26.149  1   68.63  ? 261 SER C CA  1 
ATOM   6578 C  C   . SER C 1 265 ? -63.768 20.652  26.238  1   65.3   ? 261 SER C C   1 
ATOM   6579 O  O   . SER C 1 265 ? -63.849 19.769  27.096  1   63.67  ? 261 SER C O   1 
ATOM   6580 C  CB  . SER C 1 265 ? -65.918 21.423  25.122  1   71.34  ? 261 SER C CB  1 
ATOM   6581 O  OG  . SER C 1 265 ? -65.311 21.175  23.863  1   74.01  ? 261 SER C OG  1 
ATOM   6582 N  N   . LEU C 1 266 ? -62.738 20.752  25.382  1   61.99  ? 262 LEU C N   1 
ATOM   6583 C  CA  . LEU C 1 266 ? -61.617 19.821  25.41   1   59.19  ? 262 LEU C CA  1 
ATOM   6584 C  C   . LEU C 1 266 ? -60.966 19.789  26.796  1   58.42  ? 262 LEU C C   1 
ATOM   6585 O  O   . LEU C 1 266 ? -60.615 18.72   27.283  1   57.74  ? 262 LEU C O   1 
ATOM   6586 C  CB  . LEU C 1 266 ? -60.564 20.128  24.346  1   57.93  ? 262 LEU C CB  1 
ATOM   6587 C  CG  . LEU C 1 266 ? -59.276 19.294  24.451  1   53.27  ? 262 LEU C CG  1 
ATOM   6588 C  CD1 . LEU C 1 266 ? -59.587 17.857  24.09   1   54.51  ? 262 LEU C CD1 1 
ATOM   6589 C  CD2 . LEU C 1 266 ? -58.13  19.803  23.604  1   50.26  ? 262 LEU C CD2 1 
ATOM   6590 N  N   . LEU C 1 267 ? -60.783 20.969  27.403  1   57.29  ? 263 LEU C N   1 
ATOM   6591 C  CA  . LEU C 1 267 ? -60.137 21.091  28.698  1   54.47  ? 263 LEU C CA  1 
ATOM   6592 C  C   . LEU C 1 267 ? -61     20.41   29.762  1   56.2   ? 263 LEU C C   1 
ATOM   6593 O  O   . LEU C 1 267 ? -60.506 19.719  30.66   1   54.76  ? 263 LEU C O   1 
ATOM   6594 C  CB  . LEU C 1 267 ? -59.876 22.569  29.02   1   52.77  ? 263 LEU C CB  1 
ATOM   6595 C  CG  . LEU C 1 267 ? -59.386 22.858  30.446  1   51.4   ? 263 LEU C CG  1 
ATOM   6596 C  CD1 . LEU C 1 267 ? -58.064 22.146  30.716  1   49.37  ? 263 LEU C CD1 1 
ATOM   6597 C  CD2 . LEU C 1 267 ? -59.309 24.311  30.889  1   49.88  ? 263 LEU C CD2 1 
ATOM   6598 N  N   . SER C 1 268 ? -62.308 20.658  29.674  1   59.88  ? 264 SER C N   1 
ATOM   6599 C  CA  . SER C 1 268 ? -63.219 20.22   30.717  1   61.81  ? 264 SER C CA  1 
ATOM   6600 C  C   . SER C 1 268 ? -63.457 18.717  30.599  1   62.35  ? 264 SER C C   1 
ATOM   6601 O  O   . SER C 1 268 ? -63.801 18.087  31.596  1   62.58  ? 264 SER C O   1 
ATOM   6602 C  CB  . SER C 1 268 ? -64.499 20.988  30.672  1   62.16  ? 264 SER C CB  1 
ATOM   6603 O  OG  . SER C 1 268 ? -65.07  20.807  29.388  1   64.1   ? 264 SER C OG  1 
ATOM   6604 N  N   . GLN C 1 269 ? -63.259 18.173  29.384  1   63.42  ? 265 GLN C N   1 
ATOM   6605 C  CA  . GLN C 1 269 ? -63.279 16.739  29.12   1   65.46  ? 265 GLN C CA  1 
ATOM   6606 C  C   . GLN C 1 269 ? -61.983 16.103  29.62   1   64.91  ? 265 GLN C C   1 
ATOM   6607 O  O   . GLN C 1 269 ? -61.964 14.947  30.042  1   64.27  ? 265 GLN C O   1 
ATOM   6608 C  CB  . GLN C 1 269 ? -63.454 16.447  27.633  1   66.57  ? 265 GLN C CB  1 
ATOM   6609 C  CG  . GLN C 1 269 ? -64.852 16.788  27.129  1   72.78  ? 265 GLN C CG  1 
ATOM   6610 C  CD  . GLN C 1 269 ? -65.006 16.612  25.635  1   76.3   ? 265 GLN C CD  1 
ATOM   6611 O  OE1 . GLN C 1 269 ? -65.052 17.585  24.867  1   76.91  ? 265 GLN C OE1 1 
ATOM   6612 N  NE2 . GLN C 1 269 ? -65.07  15.356  25.216  1   78.07  ? 265 GLN C NE2 1 
ATOM   6613 N  N   . MET C 1 270 ? -60.9   16.884  29.582  1   60.41  ? 266 MET C N   1 
ATOM   6614 C  CA  . MET C 1 270 ? -59.62  16.41   30.066  1   51.86  ? 266 MET C CA  1 
ATOM   6615 C  C   . MET C 1 270 ? -59.598 16.46   31.582  1   49.41  ? 266 MET C C   1 
ATOM   6616 O  O   . MET C 1 270 ? -58.846 15.709  32.195  1   49.62  ? 266 MET C O   1 
ATOM   6617 C  CB  . MET C 1 270 ? -58.447 17.19   29.472  1   49.45  ? 266 MET C CB  1 
ATOM   6618 C  CG  . MET C 1 270 ? -58.197 16.838  28.022  1   47.83  ? 266 MET C CG  1 
ATOM   6619 S  SD  . MET C 1 270 ? -56.872 17.848  27.346  1   45.33  ? 266 MET C SD  1 
ATOM   6620 C  CE  . MET C 1 270 ? -55.372 17.052  27.942  1   40.23  ? 266 MET C CE  1 
ATOM   6621 N  N   . LEU C 1 271 ? -60.472 17.278  32.173  1   50.12  ? 267 LEU C N   1 
ATOM   6622 C  CA  . LEU C 1 271 ? -60.495 17.4    33.622  1   51.11  ? 267 LEU C CA  1 
ATOM   6623 C  C   . LEU C 1 271 ? -61.773 16.827  34.24   1   56.28  ? 267 LEU C C   1 
ATOM   6624 O  O   . LEU C 1 271 ? -62.09  17.182  35.371  1   61.81  ? 267 LEU C O   1 
ATOM   6625 C  CB  . LEU C 1 271 ? -60.303 18.87   33.992  1   48.22  ? 267 LEU C CB  1 
ATOM   6626 C  CG  . LEU C 1 271 ? -58.965 19.493  33.588  1   46.07  ? 267 LEU C CG  1 
ATOM   6627 C  CD1 . LEU C 1 271 ? -58.934 20.96   34.033  1   44.72  ? 267 LEU C CD1 1 
ATOM   6628 C  CD2 . LEU C 1 271 ? -57.808 18.676  34.193  1   43.2   ? 267 LEU C CD2 1 
ATOM   6629 N  N   . HIS C 1 272 ? -62.488 15.934  33.538  1   55.73  ? 268 HIS C N   1 
ATOM   6630 C  CA  . HIS C 1 272 ? -63.691 15.321  34.082  1   57.57  ? 268 HIS C CA  1 
ATOM   6631 C  C   . HIS C 1 272 ? -63.373 14.65   35.416  1   58.06  ? 268 HIS C C   1 
ATOM   6632 O  O   . HIS C 1 272 ? -62.348 13.981  35.55   1   56.52  ? 268 HIS C O   1 
ATOM   6633 C  CB  . HIS C 1 272 ? -64.297 14.354  33.06   1   60.32  ? 268 HIS C CB  1 
ATOM   6634 C  CG  . HIS C 1 272 ? -65.765 14.111  33.22   1   63.45  ? 268 HIS C CG  1 
ATOM   6635 N  ND1 . HIS C 1 272 ? -66.38  13.787  34.414  1   63.21  ? 268 HIS C ND1 1 
ATOM   6636 C  CD2 . HIS C 1 272 ? -66.734 14.139  32.301  1   65.74  ? 268 HIS C CD2 1 
ATOM   6637 C  CE1 . HIS C 1 272 ? -67.68  13.652  34.22   1   64.58  ? 268 HIS C CE1 1 
ATOM   6638 N  NE2 . HIS C 1 272 ? -67.919 13.857  32.941  1   67.83  ? 268 HIS C NE2 1 
ATOM   6639 N  N   . TYR C 1 273 ? -64.26  14.833  36.402  1   61.62  ? 269 TYR C N   1 
ATOM   6640 C  CA  . TYR C 1 273 ? -64.018 14.306  37.736  1   66.95  ? 269 TYR C CA  1 
ATOM   6641 C  C   . TYR C 1 273 ? -64.163 12.782  37.736  1   72.28  ? 269 TYR C C   1 
ATOM   6642 O  O   . TYR C 1 273 ? -63.582 12.102  38.58   1   70.88  ? 269 TYR C O   1 
ATOM   6643 C  CB  . TYR C 1 273 ? -64.923 14.989  38.762  1   73.42  ? 269 TYR C CB  1 
ATOM   6644 C  CG  . TYR C 1 273 ? -64.548 14.778  40.226  1   79.39  ? 269 TYR C CG  1 
ATOM   6645 C  CD1 . TYR C 1 273 ? -63.548 15.55   40.811  1   80.86  ? 269 TYR C CD1 1 
ATOM   6646 C  CD2 . TYR C 1 273 ? -65.199 13.839  41.038  1   80.78  ? 269 TYR C CD2 1 
ATOM   6647 C  CE1 . TYR C 1 273 ? -63.192 15.378  42.141  1   76.74  ? 269 TYR C CE1 1 
ATOM   6648 C  CE2 . TYR C 1 273 ? -64.859 13.67   42.375  1   75.02  ? 269 TYR C CE2 1 
ATOM   6649 C  CZ  . TYR C 1 273 ? -63.845 14.442  42.923  1   73.6   ? 269 TYR C CZ  1 
ATOM   6650 O  OH  . TYR C 1 273 ? -63.426 14.339  44.218  1   72.13  ? 269 TYR C OH  1 
ATOM   6651 N  N   . ASP C 1 274 ? -64.948 12.252  36.789  1   77.65  ? 270 ASP C N   1 
ATOM   6652 C  CA  . ASP C 1 274 ? -65.102 10.812  36.657  1   80.97  ? 270 ASP C CA  1 
ATOM   6653 C  C   . ASP C 1 274 ? -64.066 10.26   35.674  1   74.93  ? 270 ASP C C   1 
ATOM   6654 O  O   . ASP C 1 274 ? -64.134 10.569  34.483  1   73.95  ? 270 ASP C O   1 
ATOM   6655 C  CB  . ASP C 1 274 ? -66.528 10.395  36.326  1   85.9   ? 270 ASP C CB  1 
ATOM   6656 C  CG  . ASP C 1 274 ? -66.682 8.903   36.072  1   91.53  ? 270 ASP C CG  1 
ATOM   6657 O  OD1 . ASP C 1 274 ? -66.361 8.114   36.989  1   94.79  ? 270 ASP C OD1 1 
ATOM   6658 O  OD2 . ASP C 1 274 ? -67.084 8.542   34.953  1   92.21  ? 270 ASP C OD2 1 
ATOM   6659 N  N   . PRO C 1 275 ? -63.116 9.412   36.154  1   67.29  ? 271 PRO C N   1 
ATOM   6660 C  CA  . PRO C 1 275 ? -62.064 8.82    35.313  1   61.17  ? 271 PRO C CA  1 
ATOM   6661 C  C   . PRO C 1 275 ? -62.549 8.097   34.056  1   61.39  ? 271 PRO C C   1 
ATOM   6662 O  O   . PRO C 1 275 ? -61.861 8.05    33.023  1   58.84  ? 271 PRO C O   1 
ATOM   6663 C  CB  . PRO C 1 275 ? -61.395 7.812   36.27   1   61.67  ? 271 PRO C CB  1 
ATOM   6664 C  CG  . PRO C 1 275 ? -61.687 8.319   37.667  1   63.97  ? 271 PRO C CG  1 
ATOM   6665 C  CD  . PRO C 1 275 ? -63.037 8.985   37.565  1   66.74  ? 271 PRO C CD  1 
ATOM   6666 N  N   . ASN C 1 276 ? -63.73  7.476   34.186  1   63.64  ? 272 ASN C N   1 
ATOM   6667 C  CA  . ASN C 1 276 ? -64.339 6.72    33.105  1   65.3   ? 272 ASN C CA  1 
ATOM   6668 C  C   . ASN C 1 276 ? -64.825 7.678   32.024  1   65.18  ? 272 ASN C C   1 
ATOM   6669 O  O   . ASN C 1 276 ? -64.865 7.323   30.849  1   64.36  ? 272 ASN C O   1 
ATOM   6670 C  CB  . ASN C 1 276 ? -65.469 5.821   33.594  1   69.32  ? 272 ASN C CB  1 
ATOM   6671 C  CG  . ASN C 1 276 ? -65.031 4.897   34.704  1   68.68  ? 272 ASN C CG  1 
ATOM   6672 O  OD1 . ASN C 1 276 ? -63.895 4.413   34.68   1   71.02  ? 272 ASN C OD1 1 
ATOM   6673 N  ND2 . ASN C 1 276 ? -65.881 4.678   35.697  1   66.36  ? 272 ASN C ND2 1 
ATOM   6674 N  N   . LYS C 1 277 ? -65.203 8.891   32.439  1   66.32  ? 273 LYS C N   1 
ATOM   6675 C  CA  . LYS C 1 277 ? -65.772 9.862   31.521  1   67.26  ? 273 LYS C CA  1 
ATOM   6676 C  C   . LYS C 1 277 ? -64.678 10.761  30.967  1   63.25  ? 273 LYS C C   1 
ATOM   6677 O  O   . LYS C 1 277 ? -64.892 11.394  29.94   1   65.46  ? 273 LYS C O   1 
ATOM   6678 C  CB  . LYS C 1 277 ? -66.911 10.643  32.179  1   71.66  ? 273 LYS C CB  1 
ATOM   6679 C  CG  . LYS C 1 277 ? -68.243 9.937   32.037  1   81.64  ? 273 LYS C CG  1 
ATOM   6680 C  CD  . LYS C 1 277 ? -69.247 10.202  33.151  1   88.4   ? 273 LYS C CD  1 
ATOM   6681 C  CE  . LYS C 1 277 ? -70.445 9.334   32.917  1   94.75  ? 273 LYS C CE  1 
ATOM   6682 N  NZ  . LYS C 1 277 ? -71.467 9.529   33.944  1   99.95  ? 273 LYS C NZ  1 
ATOM   6683 N  N   . ARG C 1 278 ? -63.54  10.833  31.673  1   59.24  ? 274 ARG C N   1 
ATOM   6684 C  CA  . ARG C 1 278 ? -62.417 11.664  31.263  1   53.88  ? 274 ARG C CA  1 
ATOM   6685 C  C   . ARG C 1 278 ? -62.017 11.241  29.857  1   53.59  ? 274 ARG C C   1 
ATOM   6686 O  O   . ARG C 1 278 ? -61.953 10.054  29.579  1   54.62  ? 274 ARG C O   1 
ATOM   6687 C  CB  . ARG C 1 278 ? -61.25  11.504  32.24   1   50.76  ? 274 ARG C CB  1 
ATOM   6688 C  CG  . ARG C 1 278 ? -60.279 12.678  32.248  1   49.31  ? 274 ARG C CG  1 
ATOM   6689 C  CD  . ARG C 1 278 ? -59.347 12.74   33.457  1   44.31  ? 274 ARG C CD  1 
ATOM   6690 N  NE  . ARG C 1 278 ? -60.051 12.707  34.741  1   44.84  ? 274 ARG C NE  1 
ATOM   6691 C  CZ  . ARG C 1 278 ? -59.63  12.05   35.827  1   46.55  ? 274 ARG C CZ  1 
ATOM   6692 N  NH1 . ARG C 1 278 ? -58.502 11.367  35.804  1   45.87  ? 274 ARG C NH1 1 
ATOM   6693 N  NH2 . ARG C 1 278 ? -60.312 12.083  36.96   1   48.01  ? 274 ARG C NH2 1 
ATOM   6694 N  N   . ILE C 1 279 ? -61.791 12.212  28.97   1   52.93  ? 275 ILE C N   1 
ATOM   6695 C  CA  . ILE C 1 279 ? -61.453 11.88   27.601  1   52.65  ? 275 ILE C CA  1 
ATOM   6696 C  C   . ILE C 1 279 ? -60.149 11.091  27.614  1   54.13  ? 275 ILE C C   1 
ATOM   6697 O  O   . ILE C 1 279 ? -59.227 11.387  28.376  1   53.41  ? 275 ILE C O   1 
ATOM   6698 C  CB  . ILE C 1 279 ? -61.416 13.115  26.679  1   51.15  ? 275 ILE C CB  1 
ATOM   6699 C  CG1 . ILE C 1 279 ? -61.653 12.721  25.212  1   52.8   ? 275 ILE C CG1 1 
ATOM   6700 C  CG2 . ILE C 1 279 ? -60.137 13.927  26.85   1   47.76  ? 275 ILE C CG2 1 
ATOM   6701 C  CD1 . ILE C 1 279 ? -61.741 13.888  24.241  1   52.11  ? 275 ILE C CD1 1 
ATOM   6702 N  N   . SER C 1 280 ? -60.118 10.033  26.808  1   55.94  ? 276 SER C N   1 
ATOM   6703 C  CA  . SER C 1 280 ? -58.866 9.365   26.513  1   55.25  ? 276 SER C CA  1 
ATOM   6704 C  C   . SER C 1 280 ? -58.089 10.259  25.553  1   54.21  ? 276 SER C C   1 
ATOM   6705 O  O   . SER C 1 280 ? -58.712 11.036  24.818  1   52.68  ? 276 SER C O   1 
ATOM   6706 C  CB  . SER C 1 280 ? -59.127 8.013   25.896  1   58.43  ? 276 SER C CB  1 
ATOM   6707 O  OG  . SER C 1 280 ? -59.591 8.152   24.556  1   59.37  ? 276 SER C OG  1 
ATOM   6708 N  N   . ALA C 1 281 ? -56.753 10.089  25.556  1   52.21  ? 277 ALA C N   1 
ATOM   6709 C  CA  . ALA C 1 281 ? -55.801 10.771  24.688  1   52.35  ? 277 ALA C CA  1 
ATOM   6710 C  C   . ALA C 1 281 ? -56.122 10.53   23.22   1   54.39  ? 277 ALA C C   1 
ATOM   6711 O  O   . ALA C 1 281 ? -56.056 11.454  22.409  1   51.9   ? 277 ALA C O   1 
ATOM   6712 C  CB  . ALA C 1 281 ? -54.411 10.268  24.957  1   49.02  ? 277 ALA C CB  1 
ATOM   6713 N  N   . LYS C 1 282 ? -56.427 9.266   22.903  1   59.02  ? 278 LYS C N   1 
ATOM   6714 C  CA  . LYS C 1 282 ? -56.635 8.838   21.531  1   60     ? 278 LYS C CA  1 
ATOM   6715 C  C   . LYS C 1 282 ? -57.854 9.577   20.996  1   61.09  ? 278 LYS C C   1 
ATOM   6716 O  O   . LYS C 1 282 ? -57.836 10.084  19.878  1   63.23  ? 278 LYS C O   1 
ATOM   6717 C  CB  . LYS C 1 282 ? -56.728 7.311   21.467  1   62.74  ? 278 LYS C CB  1 
ATOM   6718 C  CG  . LYS C 1 282 ? -56.72  6.782   20.038  1   70.63  ? 278 LYS C CG  1 
ATOM   6719 C  CD  . LYS C 1 282 ? -57.04  5.292   19.936  1   75.39  ? 278 LYS C CD  1 
ATOM   6720 C  CE  . LYS C 1 282 ? -56.034 4.429   20.644  1   71.09  ? 278 LYS C CE  1 
ATOM   6721 N  NZ  . LYS C 1 282 ? -56.346 2.999   20.575  1   66.5   ? 278 LYS C NZ  1 
ATOM   6722 N  N   . ALA C 1 283 ? -58.888 9.678   21.839  1   61.74  ? 279 ALA C N   1 
ATOM   6723 C  CA  . ALA C 1 283 ? -60.062 10.49   21.541  1   64.52  ? 279 ALA C CA  1 
ATOM   6724 C  C   . ALA C 1 283 ? -59.679 11.968  21.407  1   66.12  ? 279 ALA C C   1 
ATOM   6725 O  O   . ALA C 1 283 ? -60.038 12.613  20.429  1   68.56  ? 279 ALA C O   1 
ATOM   6726 C  CB  . ALA C 1 283 ? -61.145 10.278  22.586  1   64.18  ? 279 ALA C CB  1 
ATOM   6727 N  N   . ALA C 1 284 ? -58.922 12.517  22.367  1   62.28  ? 280 ALA C N   1 
ATOM   6728 C  CA  . ALA C 1 284 ? -58.632 13.941  22.31   1   63.46  ? 280 ALA C CA  1 
ATOM   6729 C  C   . ALA C 1 284 ? -57.988 14.344  20.977  1   63.38  ? 280 ALA C C   1 
ATOM   6730 O  O   . ALA C 1 284 ? -58.183 15.467  20.52   1   65.88  ? 280 ALA C O   1 
ATOM   6731 C  CB  . ALA C 1 284 ? -57.818 14.372  23.507  1   59.27  ? 280 ALA C CB  1 
ATOM   6732 N  N   . LEU C 1 285 ? -57.243 13.433  20.34   1   60.25  ? 281 LEU C N   1 
ATOM   6733 C  CA  . LEU C 1 285 ? -56.54  13.755  19.107  1   61.51  ? 281 LEU C CA  1 
ATOM   6734 C  C   . LEU C 1 285 ? -57.541 14.113  18.009  1   66.58  ? 281 LEU C C   1 
ATOM   6735 O  O   . LEU C 1 285 ? -57.204 14.822  17.059  1   69.69  ? 281 LEU C O   1 
ATOM   6736 C  CB  . LEU C 1 285 ? -55.616 12.616  18.672  1   59.19  ? 281 LEU C CB  1 
ATOM   6737 C  CG  . LEU C 1 285 ? -54.373 12.376  19.544  1   56.11  ? 281 LEU C CG  1 
ATOM   6738 C  CD1 . LEU C 1 285 ? -53.701 11.018  19.334  1   51.57  ? 281 LEU C CD1 1 
ATOM   6739 C  CD2 . LEU C 1 285 ? -53.38  13.506  19.333  1   52.84  ? 281 LEU C CD2 1 
ATOM   6740 N  N   . ALA C 1 286 ? -58.767 13.595  18.138  1   68.63  ? 282 ALA C N   1 
ATOM   6741 C  CA  . ALA C 1 286 ? -59.786 13.76   17.111  1   72.57  ? 282 ALA C CA  1 
ATOM   6742 C  C   . ALA C 1 286 ? -60.556 15.063  17.333  1   74.53  ? 282 ALA C C   1 
ATOM   6743 O  O   . ALA C 1 286 ? -61.126 15.596  16.385  1   75.03  ? 282 ALA C O   1 
ATOM   6744 C  CB  . ALA C 1 286 ? -60.699 12.548  17.056  1   68.32  ? 282 ALA C CB  1 
ATOM   6745 N  N   . HIS C 1 287 ? -60.533 15.578  18.577  1   71.54  ? 283 HIS C N   1 
ATOM   6746 C  CA  . HIS C 1 287 ? -61.306 16.747  18.976  1   72.15  ? 283 HIS C CA  1 
ATOM   6747 C  C   . HIS C 1 287 ? -61.202 17.867  17.935  1   76.05  ? 283 HIS C C   1 
ATOM   6748 O  O   . HIS C 1 287 ? -60.133 18.056  17.34   1   77.2   ? 283 HIS C O   1 
ATOM   6749 C  CB  . HIS C 1 287 ? -60.865 17.25   20.353  1   65.79  ? 283 HIS C CB  1 
ATOM   6750 C  CG  . HIS C 1 287 ? -61.813 18.232  20.952  1   65.21  ? 283 HIS C CG  1 
ATOM   6751 N  ND1 . HIS C 1 287 ? -61.92  19.536  20.515  1   65.87  ? 283 HIS C ND1 1 
ATOM   6752 C  CD2 . HIS C 1 287 ? -62.716 18.093  21.932  1   64.72  ? 283 HIS C CD2 1 
ATOM   6753 C  CE1 . HIS C 1 287 ? -62.848 20.161  21.228  1   67.05  ? 283 HIS C CE1 1 
ATOM   6754 N  NE2 . HIS C 1 287 ? -63.344 19.302  22.101  1   66.13  ? 283 HIS C NE2 1 
ATOM   6755 N  N   . PRO C 1 288 ? -62.313 18.625  17.689  1   76.69  ? 284 PRO C N   1 
ATOM   6756 C  CA  . PRO C 1 288 ? -62.323 19.766  16.758  1   74.39  ? 284 PRO C CA  1 
ATOM   6757 C  C   . PRO C 1 288 ? -61.254 20.836  16.981  1   70.43  ? 284 PRO C C   1 
ATOM   6758 O  O   . PRO C 1 288 ? -60.766 21.433  16.021  1   68.62  ? 284 PRO C O   1 
ATOM   6759 C  CB  . PRO C 1 288 ? -63.75  20.356  16.853  1   76.16  ? 284 PRO C CB  1 
ATOM   6760 C  CG  . PRO C 1 288 ? -64.346 19.755  18.113  1   75.82  ? 284 PRO C CG  1 
ATOM   6761 C  CD  . PRO C 1 288 ? -63.642 18.415  18.301  1   76.15  ? 284 PRO C CD  1 
ATOM   6762 N  N   . PHE C 1 289 ? -60.884 21.035  18.256  1   66.87  ? 285 PHE C N   1 
ATOM   6763 C  CA  . PHE C 1 289 ? -59.861 21.988  18.648  1   64.25  ? 285 PHE C CA  1 
ATOM   6764 C  C   . PHE C 1 289 ? -58.644 21.845  17.736  1   65.11  ? 285 PHE C C   1 
ATOM   6765 O  O   . PHE C 1 289 ? -57.953 22.823  17.464  1   64.84  ? 285 PHE C O   1 
ATOM   6766 C  CB  . PHE C 1 289 ? -59.621 21.894  20.16   1   60.57  ? 285 PHE C CB  1 
ATOM   6767 C  CG  . PHE C 1 289 ? -58.559 22.843  20.697  1   58.62  ? 285 PHE C CG  1 
ATOM   6768 C  CD1 . PHE C 1 289 ? -58.828 24.195  20.884  1   59.82  ? 285 PHE C CD1 1 
ATOM   6769 C  CD2 . PHE C 1 289 ? -57.298 22.367  21.04   1   57.55  ? 285 PHE C CD2 1 
ATOM   6770 C  CE1 . PHE C 1 289 ? -57.858 25.052  21.38   1   59.24  ? 285 PHE C CE1 1 
ATOM   6771 C  CE2 . PHE C 1 289 ? -56.321 23.221  21.527  1   56.81  ? 285 PHE C CE2 1 
ATOM   6772 C  CZ  . PHE C 1 289 ? -56.607 24.566  21.699  1   59.92  ? 285 PHE C CZ  1 
ATOM   6773 N  N   . PHE C 1 290 ? -58.433 20.633  17.211  1   67.14  ? 286 PHE C N   1 
ATOM   6774 C  CA  . PHE C 1 290 ? -57.219 20.352  16.464  1   68.41  ? 286 PHE C CA  1 
ATOM   6775 C  C   . PHE C 1 290 ? -57.455 20.336  14.961  1   76.35  ? 286 PHE C C   1 
ATOM   6776 O  O   . PHE C 1 290 ? -56.584 19.897  14.217  1   77.92  ? 286 PHE C O   1 
ATOM   6777 C  CB  . PHE C 1 290 ? -56.598 19.016  16.863  1   63.58  ? 286 PHE C CB  1 
ATOM   6778 C  CG  . PHE C 1 290 ? -56.107 19.007  18.298  1   59.06  ? 286 PHE C CG  1 
ATOM   6779 C  CD1 . PHE C 1 290 ? -55.007 19.771  18.664  1   55.67  ? 286 PHE C CD1 1 
ATOM   6780 C  CD2 . PHE C 1 290 ? -56.751 18.246  19.269  1   57.92  ? 286 PHE C CD2 1 
ATOM   6781 C  CE1 . PHE C 1 290 ? -54.556 19.756  19.972  1   53.98  ? 286 PHE C CE1 1 
ATOM   6782 C  CE2 . PHE C 1 290 ? -56.302 18.245  20.582  1   55.66  ? 286 PHE C CE2 1 
ATOM   6783 C  CZ  . PHE C 1 290 ? -55.208 19.003  20.93   1   53.34  ? 286 PHE C CZ  1 
ATOM   6784 N  N   . GLN C 1 291 ? -58.599 20.843  14.501  1   85.59  ? 287 GLN C N   1 
ATOM   6785 C  CA  . GLN C 1 291 ? -58.845 20.836  13.065  1   91.82  ? 287 GLN C CA  1 
ATOM   6786 C  C   . GLN C 1 291 ? -57.741 21.618  12.343  1   90.6   ? 287 GLN C C   1 
ATOM   6787 O  O   . GLN C 1 291 ? -57.148 21.12   11.386  1   86.56  ? 287 GLN C O   1 
ATOM   6788 C  CB  . GLN C 1 291 ? -60.276 21.269  12.734  1   98.56  ? 287 GLN C CB  1 
ATOM   6789 C  CG  . GLN C 1 291 ? -61.341 20.201  12.977  1   105.66 ? 287 GLN C CG  1 
ATOM   6790 C  CD  . GLN C 1 291 ? -62.755 20.712  12.779  1   119.46 ? 287 GLN C CD  1 
ATOM   6791 O  OE1 . GLN C 1 291 ? -63.275 21.509  13.57   1   118.75 ? 287 GLN C OE1 1 
ATOM   6792 N  NE2 . GLN C 1 291 ? -63.404 20.262  11.713  1   125.04 ? 287 GLN C NE2 1 
ATOM   6793 N  N   . ASP C 1 292 ? -57.433 22.821  12.848  1   90.11  ? 288 ASP C N   1 
ATOM   6794 C  CA  . ASP C 1 292 ? -56.651 23.798  12.104  1   94.43  ? 288 ASP C CA  1 
ATOM   6795 C  C   . ASP C 1 292 ? -55.16  23.698  12.445  1   92.37  ? 288 ASP C C   1 
ATOM   6796 O  O   . ASP C 1 292 ? -54.386 24.532  11.975  1   92.45  ? 288 ASP C O   1 
ATOM   6797 C  CB  . ASP C 1 292 ? -57.248 25.2    12.239  1   99.07  ? 288 ASP C CB  1 
ATOM   6798 C  CG  . ASP C 1 292 ? -57.33  25.801  13.644  1   95.02  ? 288 ASP C CG  1 
ATOM   6799 O  OD1 . ASP C 1 292 ? -56.844 25.156  14.604  1   88.36  ? 288 ASP C OD1 1 
ATOM   6800 O  OD2 . ASP C 1 292 ? -57.878 26.922  13.775  1   91.17  ? 288 ASP C OD2 1 
ATOM   6801 N  N   . VAL C 1 293 ? -54.766 22.659  13.209  1   86.64  ? 289 VAL C N   1 
ATOM   6802 C  CA  . VAL C 1 293 ? -53.482 22.607  13.904  1   80.64  ? 289 VAL C CA  1 
ATOM   6803 C  C   . VAL C 1 293 ? -52.326 22.656  12.906  1   78.2   ? 289 VAL C C   1 
ATOM   6804 O  O   . VAL C 1 293 ? -52.381 22.003  11.869  1   80.31  ? 289 VAL C O   1 
ATOM   6805 C  CB  . VAL C 1 293 ? -53.345 21.399  14.854  1   80.3   ? 289 VAL C CB  1 
ATOM   6806 C  CG1 . VAL C 1 293 ? -53.048 20.103  14.108  1   81.44  ? 289 VAL C CG1 1 
ATOM   6807 C  CG2 . VAL C 1 293 ? -52.267 21.641  15.903  1   75.61  ? 289 VAL C CG2 1 
ATOM   6808 N  N   . THR C 1 294 ? -51.302 23.464  13.227  1   77.34  ? 290 THR C N   1 
ATOM   6809 C  CA  . THR C 1 294 ? -50.052 23.542  12.473  1   76.32  ? 290 THR C CA  1 
ATOM   6810 C  C   . THR C 1 294 ? -48.888 23.211  13.41   1   75.7   ? 290 THR C C   1 
ATOM   6811 O  O   . THR C 1 294 ? -49.102 22.654  14.493  1   70.18  ? 290 THR C O   1 
ATOM   6812 C  CB  . THR C 1 294 ? -49.864 24.908  11.8    1   77.87  ? 290 THR C CB  1 
ATOM   6813 O  OG1 . THR C 1 294 ? -49.666 25.882  12.825  1   76.06  ? 290 THR C OG1 1 
ATOM   6814 C  CG2 . THR C 1 294 ? -51.004 25.301  10.871  1   77.78  ? 290 THR C CG2 1 
ATOM   6815 N  N   . LYS C 1 295 ? -47.666 23.574  12.987  1   75.23  ? 291 LYS C N   1 
ATOM   6816 C  CA  . LYS C 1 295 ? -46.476 23.321  13.785  1   72.44  ? 291 LYS C CA  1 
ATOM   6817 C  C   . LYS C 1 295 ? -45.592 24.57   13.873  1   70.67  ? 291 LYS C C   1 
ATOM   6818 O  O   . LYS C 1 295 ? -44.498 24.563  13.312  1   68.36  ? 291 LYS C O   1 
ATOM   6819 C  CB  . LYS C 1 295 ? -45.651 22.169  13.195  1   76.06  ? 291 LYS C CB  1 
ATOM   6820 C  CG  . LYS C 1 295 ? -44.924 21.31   14.24   1   75.81  ? 291 LYS C CG  1 
ATOM   6821 C  CD  . LYS C 1 295 ? -43.536 20.783  13.884  1   74.56  ? 291 LYS C CD  1 
ATOM   6822 C  CE  . LYS C 1 295 ? -43.056 19.678  14.786  1   74.32  ? 291 LYS C CE  1 
ATOM   6823 N  NZ  . LYS C 1 295 ? -41.599 19.503  14.769  1   69.35  ? 291 LYS C NZ  1 
ATOM   6824 N  N   . PRO C 1 296 ? -45.971 25.638  14.632  1   69.47  ? 292 PRO C N   1 
ATOM   6825 C  CA  . PRO C 1 296 ? -45.148 26.853  14.724  1   68.56  ? 292 PRO C CA  1 
ATOM   6826 C  C   . PRO C 1 296 ? -43.794 26.649  15.404  1   68.99  ? 292 PRO C C   1 
ATOM   6827 O  O   . PRO C 1 296 ? -43.593 25.665  16.113  1   66.06  ? 292 PRO C O   1 
ATOM   6828 C  CB  . PRO C 1 296 ? -46.007 27.889  15.479  1   64.85  ? 292 PRO C CB  1 
ATOM   6829 C  CG  . PRO C 1 296 ? -47.329 27.194  15.783  1   63.97  ? 292 PRO C CG  1 
ATOM   6830 C  CD  . PRO C 1 296 ? -47.18  25.718  15.475  1   66.34  ? 292 PRO C CD  1 
ATOM   6831 N  N   . VAL C 1 297 ? -42.868 27.587  15.163  1   72.41  ? 293 VAL C N   1 
ATOM   6832 C  CA  . VAL C 1 297 ? -41.592 27.631  15.866  1   74.01  ? 293 VAL C CA  1 
ATOM   6833 C  C   . VAL C 1 297 ? -41.779 28.471  17.132  1   73.49  ? 293 VAL C C   1 
ATOM   6834 O  O   . VAL C 1 297 ? -42.598 29.383  17.126  1   68.7   ? 293 VAL C O   1 
ATOM   6835 C  CB  . VAL C 1 297 ? -40.488 28.193  14.943  1   74.41  ? 293 VAL C CB  1 
ATOM   6836 C  CG1 . VAL C 1 297 ? -39.26  28.686  15.711  1   69.1   ? 293 VAL C CG1 1 
ATOM   6837 C  CG2 . VAL C 1 297 ? -40.088 27.18   13.87   1   73.5   ? 293 VAL C CG2 1 
ATOM   6838 N  N   . PRO C 1 298 ? -41.092 28.181  18.268  1   76.1   ? 294 PRO C N   1 
ATOM   6839 C  CA  . PRO C 1 298 ? -41.225 29.009  19.471  1   74.85  ? 294 PRO C CA  1 
ATOM   6840 C  C   . PRO C 1 298 ? -40.197 30.129  19.407  1   80.95  ? 294 PRO C C   1 
ATOM   6841 O  O   . PRO C 1 298 ? -39.155 29.968  18.773  1   88.57  ? 294 PRO C O   1 
ATOM   6842 C  CB  . PRO C 1 298 ? -40.894 28.022  20.575  1   72.2   ? 294 PRO C CB  1 
ATOM   6843 C  CG  . PRO C 1 298 ? -39.824 27.161  19.951  1   74.28  ? 294 PRO C CG  1 
ATOM   6844 C  CD  . PRO C 1 298 ? -40.179 27.042  18.469  1   73.73  ? 294 PRO C CD  1 
ATOM   6845 N  N   . HIS C 1 299 ? -40.506 31.244  20.075  1   86.53  ? 295 HIS C N   1 
ATOM   6846 C  CA  . HIS C 1 299 ? -39.639 32.407  20.073  1   91.98  ? 295 HIS C CA  1 
ATOM   6847 C  C   . HIS C 1 299 ? -38.773 32.336  21.323  1   88.84  ? 295 HIS C C   1 
ATOM   6848 O  O   . HIS C 1 299 ? -39.256 32.622  22.423  1   87.57  ? 295 HIS C O   1 
ATOM   6849 C  CB  . HIS C 1 299 ? -40.448 33.703  19.934  1   103.62 ? 295 HIS C CB  1 
ATOM   6850 C  CG  . HIS C 1 299 ? -39.575 34.913  20.031  1   123.17 ? 295 HIS C CG  1 
ATOM   6851 N  ND1 . HIS C 1 299 ? -39.219 35.472  21.243  1   125.86 ? 295 HIS C ND1 1 
ATOM   6852 C  CD2 . HIS C 1 299 ? -38.953 35.64   19.084  1   126.49 ? 295 HIS C CD2 1 
ATOM   6853 C  CE1 . HIS C 1 299 ? -38.426 36.515  21.026  1   126.12 ? 295 HIS C CE1 1 
ATOM   6854 N  NE2 . HIS C 1 299 ? -38.254 36.636  19.722  1   132.28 ? 295 HIS C NE2 1 
ATOM   6855 N  N   . LEU C 1 300 ? -37.513 31.921  21.109  1   90.23  ? 296 LEU C N   1 
ATOM   6856 C  CA  . LEU C 1 300 ? -36.514 31.726  22.149  1   89.01  ? 296 LEU C CA  1 
ATOM   6857 C  C   . LEU C 1 300 ? -35.465 32.847  22.034  1   89.65  ? 296 LEU C C   1 
ATOM   6858 O  O   . LEU C 1 300 ? -34.264 32.522  22.156  1   87.9   ? 296 LEU C O   1 
ATOM   6859 C  CB  . LEU C 1 300 ? -35.863 30.342  22.056  1   81.69  ? 296 LEU C CB  1 
ATOM   6860 C  CG  . LEU C 1 300 ? -36.786 29.117  22.103  1   77.5   ? 296 LEU C CG  1 
ATOM   6861 C  CD1 . LEU C 1 300 ? -36.059 27.89   21.567  1   73.05  ? 296 LEU C CD1 1 
ATOM   6862 C  CD2 . LEU C 1 300 ? -37.332 28.84   23.496  1   74.04  ? 296 LEU C CD2 1 
ATOM   6863 N  N   . GLY D 2 1   ? -65.122 0.623   32.641  1   70.07  ? 171 GLY D N   1 
ATOM   6864 C  CA  . GLY D 2 1   ? -64.384 1.797   33.142  1   70.54  ? 171 GLY D CA  1 
ATOM   6865 C  C   . GLY D 2 1   ? -62.932 1.825   32.658  1   68.91  ? 171 GLY D C   1 
ATOM   6866 O  O   . GLY D 2 1   ? -62.428 0.865   32.074  1   68.15  ? 171 GLY D O   1 
ATOM   6867 N  N   . VAL D 2 2   ? -62.263 2.948   32.931  1   68.72  ? 172 VAL D N   1 
ATOM   6868 C  CA  . VAL D 2 2   ? -60.943 3.231   32.404  1   68.09  ? 172 VAL D CA  1 
ATOM   6869 C  C   . VAL D 2 2   ? -59.94  2.221   32.97   1   67.18  ? 172 VAL D C   1 
ATOM   6870 O  O   . VAL D 2 2   ? -58.819 2.137   32.477  1   67.44  ? 172 VAL D O   1 
ATOM   6871 C  CB  . VAL D 2 2   ? -60.532 4.692   32.694  1   68.89  ? 172 VAL D CB  1 
ATOM   6872 C  CG1 . VAL D 2 2   ? -60.267 4.938   34.183  1   68.75  ? 172 VAL D CG1 1 
ATOM   6873 C  CG2 . VAL D 2 2   ? -59.345 5.146   31.846  1   65.46  ? 172 VAL D CG2 1 
ATOM   6874 N  N   . ASN D 2 3   ? -60.343 1.446   33.988  1   66.82  ? 173 ASN D N   1 
ATOM   6875 C  CA  . ASN D 2 3   ? -59.469 0.445   34.586  1   63.63  ? 173 ASN D CA  1 
ATOM   6876 C  C   . ASN D 2 3   ? -59.281 -0.73   33.63   1   63.4   ? 173 ASN D C   1 
ATOM   6877 O  O   . ASN D 2 3   ? -58.323 -1.483  33.759  1   60.14  ? 173 ASN D O   1 
ATOM   6878 C  CB  . ASN D 2 3   ? -59.962 0.001   35.957  1   65.48  ? 173 ASN D CB  1 
ATOM   6879 C  CG  . ASN D 2 3   ? -60.04  1.147   36.94   1   73.16  ? 173 ASN D CG  1 
ATOM   6880 O  OD1 . ASN D 2 3   ? -59.349 2.169   36.799  1   72.55  ? 173 ASN D OD1 1 
ATOM   6881 N  ND2 . ASN D 2 3   ? -60.871 0.993   37.962  1   78.59  ? 173 ASN D ND2 1 
ATOM   6882 N  N   . GLU D 2 4   ? -60.212 -0.883  32.68   1   67.92  ? 174 GLU D N   1 
ATOM   6883 C  CA  . GLU D 2 4   ? -60.158 -1.945  31.689  1   68.88  ? 174 GLU D CA  1 
ATOM   6884 C  C   . GLU D 2 4   ? -59.611 -1.354  30.395  1   68.41  ? 174 GLU D C   1 
ATOM   6885 O  O   . GLU D 2 4   ? -59.577 -2.03   29.374  1   67.16  ? 174 GLU D O   1 
ATOM   6886 C  CB  . GLU D 2 4   ? -61.524 -2.611  31.484  1   74.8   ? 174 GLU D CB  1 
ATOM   6887 C  CG  . GLU D 2 4   ? -62.023 -3.427  32.679  1   77.96  ? 174 GLU D CG  1 
ATOM   6888 C  CD  . GLU D 2 4   ? -63.446 -3.975  32.616  1   85.66  ? 174 GLU D CD  1 
ATOM   6889 O  OE1 . GLU D 2 4   ? -64.047 -4.099  31.516  1   86.07  ? 174 GLU D OE1 1 
ATOM   6890 O  OE2 . GLU D 2 4   ? -63.972 -4.263  33.714  1   87.09  ? 174 GLU D OE2 1 
ATOM   6891 N  N   . VAL D 2 5   ? -59.168 -0.102  30.482  1   67.76  ? 175 VAL D N   1 
ATOM   6892 C  CA  . VAL D 2 5   ? -58.584 0.604   29.302  1   67.19  ? 175 VAL D CA  1 
ATOM   6893 C  C   . VAL D 2 5   ? -59.391 0.274   28.033  1   68.03  ? 175 VAL D C   1 
ATOM   6894 O  O   . VAL D 2 5   ? -58.806 -0.332  27.123  1   67.98  ? 175 VAL D O   1 
ATOM   6895 C  CB  . VAL D 2 5   ? -57.082 0.307   29.108  1   62.68  ? 175 VAL D CB  1 
ATOM   6896 C  CG1 . VAL D 2 5   ? -56.548 0.941   27.832  1   61.06  ? 175 VAL D CG1 1 
ATOM   6897 C  CG2 . VAL D 2 5   ? -56.239 0.747   30.298  1   60.05  ? 175 VAL D CG2 1 
ATOM   6898 N  N   . PRO D 2 6   ? -60.665 0.697   27.891  1   70.01  ? 176 PRO D N   1 
ATOM   6899 C  CA  . PRO D 2 6   ? -61.414 0.358   26.674  1   71.44  ? 176 PRO D CA  1 
ATOM   6900 C  C   . PRO D 2 6   ? -60.851 0.912   25.362  1   72.58  ? 176 PRO D C   1 
ATOM   6901 O  O   . PRO D 2 6   ? -60.907 0.251   24.336  1   74.21  ? 176 PRO D O   1 
ATOM   6902 C  CB  . PRO D 2 6   ? -62.839 0.858   26.953  1   74.25  ? 176 PRO D CB  1 
ATOM   6903 C  CG  . PRO D 2 6   ? -62.685 1.872   28.085  1   73.94  ? 176 PRO D CG  1 
ATOM   6904 C  CD  . PRO D 2 6   ? -61.431 1.5     28.861  1   70.72  ? 176 PRO D CD  1 
ATOM   6905 N  N   . ASP D 2 7   ? -60.252 2.105   25.395  1   73.15  ? 177 ASP D N   1 
ATOM   6906 C  CA  . ASP D 2 7   ? -59.796 2.734   24.166  1   74.04  ? 177 ASP D CA  1 
ATOM   6907 C  C   . ASP D 2 7   ? -58.465 2.142   23.694  1   71.65  ? 177 ASP D C   1 
ATOM   6908 O  O   . ASP D 2 7   ? -58.022 2.509   22.605  1   71.94  ? 177 ASP D O   1 
ATOM   6909 C  CB  . ASP D 2 7   ? -59.78  4.255   24.27   1   76.9   ? 177 ASP D CB  1 
ATOM   6910 C  CG  . ASP D 2 7   ? -61.121 4.952   24.073  1   83.71  ? 177 ASP D CG  1 
ATOM   6911 O  OD1 . ASP D 2 7   ? -62.127 4.239   23.889  1   89.18  ? 177 ASP D OD1 1 
ATOM   6912 O  OD2 . ASP D 2 7   ? -61.159 6.202   24.083  1   85.39  ? 177 ASP D OD2 1 
ATOM   6913 N  N   . TYR D 2 8   ? -57.803 1.294   24.486  1   67.24  ? 178 TYR D N   1 
ATOM   6914 C  CA  . TYR D 2 8   ? -56.448 0.846   24.047  1   64.44  ? 178 TYR D CA  1 
ATOM   6915 C  C   . TYR D 2 8   ? -56.237 -0.659  24.227  1   66.66  ? 178 TYR D C   1 
ATOM   6916 O  O   . TYR D 2 8   ? -55.262 -1.177  23.661  1   70.26  ? 178 TYR D O   1 
ATOM   6917 C  CB  . TYR D 2 8   ? -55.327 1.584   24.785  1   59.25  ? 178 TYR D CB  1 
ATOM   6918 C  CG  . TYR D 2 8   ? -55.359 3.105   24.817  1   58.23  ? 178 TYR D CG  1 
ATOM   6919 C  CD1 . TYR D 2 8   ? -56.02  3.787   25.829  1   58.38  ? 178 TYR D CD1 1 
ATOM   6920 C  CD2 . TYR D 2 8   ? -54.694 3.853   23.858  1   58.25  ? 178 TYR D CD2 1 
ATOM   6921 C  CE1 . TYR D 2 8   ? -56.046 5.169   25.869  1   59.29  ? 178 TYR D CE1 1 
ATOM   6922 C  CE2 . TYR D 2 8   ? -54.708 5.235   23.887  1   59.89  ? 178 TYR D CE2 1 
ATOM   6923 C  CZ  . TYR D 2 8   ? -55.387 5.893   24.895  1   60.02  ? 178 TYR D CZ  1 
ATOM   6924 O  OH  . TYR D 2 8   ? -55.407 7.25    24.93   1   61.14  ? 178 TYR D OH  1 
ATOM   6925 N  N   . HIS D 2 9   ? -57.119 -1.353  24.938  1   69.71  ? 179 HIS D N   1 
ATOM   6926 C  CA  . HIS D 2 9   ? -56.892 -2.799  25.224  1   72.84  ? 179 HIS D CA  1 
ATOM   6927 C  C   . HIS D 2 9   ? -56.517 -3.584  23.958  1   73.31  ? 179 HIS D C   1 
ATOM   6928 O  O   . HIS D 2 9   ? -55.836 -4.613  24.082  1   72.03  ? 179 HIS D O   1 
ATOM   6929 C  CB  . HIS D 2 9   ? -58.089 -3.418  25.958  1   78.73  ? 179 HIS D CB  1 
ATOM   6930 C  CG  . HIS D 2 9   ? -59.354 -3.54   25.176  1   91.74  ? 179 HIS D CG  1 
ATOM   6931 N  ND1 . HIS D 2 9   ? -59.489 -4.308  24.041  1   97.08  ? 179 HIS D ND1 1 
ATOM   6932 C  CD2 . HIS D 2 9   ? -60.557 -3.007  25.404  1   95.11  ? 179 HIS D CD2 1 
ATOM   6933 C  CE1 . HIS D 2 9   ? -60.73  -4.215  23.594  1   97.28  ? 179 HIS D CE1 1 
ATOM   6934 N  NE2 . HIS D 2 9   ? -61.397 -3.432  24.409  1   98.89  ? 179 HIS D NE2 1 
ATOM   6935 N  N   . GLU D 2 10  ? -56.935 -3.112  22.788  1   73.05  ? 180 GLU D N   1 
ATOM   6936 C  CA  . GLU D 2 10  ? -56.654 -3.854  21.537  1   74.09  ? 180 GLU D CA  1 
ATOM   6937 C  C   . GLU D 2 10  ? -55.244 -3.51   21.054  1   72.47  ? 180 GLU D C   1 
ATOM   6938 O  O   . GLU D 2 10  ? -54.465 -4.446  20.84   1   72.2   ? 180 GLU D O   1 
ATOM   6939 C  CB  . GLU D 2 10  ? -57.703 -3.558  20.468  1   78.88  ? 180 GLU D CB  1 
ATOM   6940 C  CG  . GLU D 2 10  ? -57.502 -4.352  19.182  1   83.79  ? 180 GLU D CG  1 
ATOM   6941 C  CD  . GLU D 2 10  ? -58.575 -4.088  18.145  1   93.76  ? 180 GLU D CD  1 
ATOM   6942 O  OE1 . GLU D 2 10  ? -59.459 -3.251  18.419  1   98.5   ? 180 GLU D OE1 1 
ATOM   6943 O  OE2 . GLU D 2 10  ? -58.528 -4.712  17.066  1   98.41  ? 180 GLU D OE2 1 
ATOM   6944 N  N   . ASP D 2 11  ? -54.955 -2.172  20.937  1   72.15  ? 181 ASP D N   1 
ATOM   6945 C  CA  . ASP D 2 11  ? -53.56  -1.829  20.551  1   70.17  ? 181 ASP D CA  1 
ATOM   6946 C  C   . ASP D 2 11  ? -52.608 -2.53   21.518  1   65.01  ? 181 ASP D C   1 
ATOM   6947 O  O   . ASP D 2 11  ? -51.554 -3.004  21.073  1   64.78  ? 181 ASP D O   1 
ATOM   6948 C  CB  . ASP D 2 11  ? -53.348 -0.324  20.508  1   69.25  ? 181 ASP D CB  1 
ATOM   6949 C  CG  . ASP D 2 11  ? -54.026 0.411   19.364  1   73.83  ? 181 ASP D CG  1 
ATOM   6950 O  OD1 . ASP D 2 11  ? -54.453 -0.263  18.405  1   77.01  ? 181 ASP D OD1 1 
ATOM   6951 O  OD2 . ASP D 2 11  ? -54.131 1.649   19.455  1   76.37  ? 181 ASP D OD2 1 
ATOM   6952 N  N   . ILE D 2 12  ? -52.972 -2.644  22.755  1   60.59  ? 182 ILE D N   1 
ATOM   6953 C  CA  . ILE D 2 12  ? -52.126 -3.17   23.809  1   59.66  ? 182 ILE D CA  1 
ATOM   6954 C  C   . ILE D 2 12  ? -51.905 -4.664  23.572  1   61.68  ? 182 ILE D C   1 
ATOM   6955 O  O   . ILE D 2 12  ? -50.783 -5.153  23.701  1   62.13  ? 182 ILE D O   1 
ATOM   6956 C  CB  . ILE D 2 12  ? -52.703 -2.867  25.207  1   57.72  ? 182 ILE D CB  1 
ATOM   6957 C  CG1 . ILE D 2 12  ? -52.487 -1.411  25.625  1   54.27  ? 182 ILE D CG1 1 
ATOM   6958 C  CG2 . ILE D 2 12  ? -52.139 -3.826  26.264  1   55.03  ? 182 ILE D CG2 1 
ATOM   6959 C  CD1 . ILE D 2 12  ? -53.303 -1.025  26.844  1   52.32  ? 182 ILE D CD1 1 
ATOM   6960 N  N   . HIS D 2 13  ? -52.995 -5.374  23.244  1   63.16  ? 183 HIS D N   1 
ATOM   6961 C  CA  . HIS D 2 13  ? -52.974 -6.792  22.929  1   58.57  ? 183 HIS D CA  1 
ATOM   6962 C  C   . HIS D 2 13  ? -52.055 -7.042  21.729  1   57.09  ? 183 HIS D C   1 
ATOM   6963 O  O   . HIS D 2 13  ? -51.132 -7.854  21.822  1   55.74  ? 183 HIS D O   1 
ATOM   6964 C  CB  . HIS D 2 13  ? -54.411 -7.304  22.79   1   64.28  ? 183 HIS D CB  1 
ATOM   6965 C  CG  . HIS D 2 13  ? -54.476 -8.7    22.262  1   67.53  ? 183 HIS D CG  1 
ATOM   6966 N  ND1 . HIS D 2 13  ? -54.518 -9.809  23.084  1   65.83  ? 183 HIS D ND1 1 
ATOM   6967 C  CD2 . HIS D 2 13  ? -54.459 -9.15   20.992  1   66.69  ? 183 HIS D CD2 1 
ATOM   6968 C  CE1 . HIS D 2 13  ? -54.497 -10.893 22.327  1   68.9   ? 183 HIS D CE1 1 
ATOM   6969 N  NE2 . HIS D 2 13  ? -54.469 -10.512 21.056  1   72.21  ? 183 HIS D NE2 1 
ATOM   6970 N  N   . THR D 2 14  ? -52.293 -6.313  20.627  1   56.88  ? 184 THR D N   1 
ATOM   6971 C  CA  . THR D 2 14  ? -51.505 -6.402  19.404  1   57.28  ? 184 THR D CA  1 
ATOM   6972 C  C   . THR D 2 14  ? -50.004 -6.268  19.692  1   56.92  ? 184 THR D C   1 
ATOM   6973 O  O   . THR D 2 14  ? -49.198 -7.002  19.109  1   56.81  ? 184 THR D O   1 
ATOM   6974 C  CB  . THR D 2 14  ? -52.015 -5.361  18.404  1   59.35  ? 184 THR D CB  1 
ATOM   6975 O  OG1 . THR D 2 14  ? -53.215 -5.91   17.87   1   61.67  ? 184 THR D OG1 1 
ATOM   6976 C  CG2 . THR D 2 14  ? -51.087 -5.125  17.226  1   59.35  ? 184 THR D CG2 1 
ATOM   6977 N  N   . TYR D 2 15  ? -49.642 -5.325  20.581  1   55.95  ? 185 TYR D N   1 
ATOM   6978 C  CA  . TYR D 2 15  ? -48.254 -5.04   20.919  1   54.22  ? 185 TYR D CA  1 
ATOM   6979 C  C   . TYR D 2 15  ? -47.684 -6.153  21.801  1   52.39  ? 185 TYR D C   1 
ATOM   6980 O  O   . TYR D 2 15  ? -46.539 -6.565  21.617  1   54.07  ? 185 TYR D O   1 
ATOM   6981 C  CB  . TYR D 2 15  ? -48.092 -3.645  21.536  1   53.59  ? 185 TYR D CB  1 
ATOM   6982 C  CG  . TYR D 2 15  ? -46.662 -3.287  21.932  1   53.93  ? 185 TYR D CG  1 
ATOM   6983 C  CD1 . TYR D 2 15  ? -45.694 -3.091  20.953  1   56.67  ? 185 TYR D CD1 1 
ATOM   6984 C  CD2 . TYR D 2 15  ? -46.275 -3.132  23.266  1   51.43  ? 185 TYR D CD2 1 
ATOM   6985 C  CE1 . TYR D 2 15  ? -44.392 -2.756  21.284  1   55.32  ? 185 TYR D CE1 1 
ATOM   6986 C  CE2 . TYR D 2 15  ? -44.976 -2.791  23.612  1   50.23  ? 185 TYR D CE2 1 
ATOM   6987 C  CZ  . TYR D 2 15  ? -44.035 -2.592  22.614  1   53.51  ? 185 TYR D CZ  1 
ATOM   6988 O  OH  . TYR D 2 15  ? -42.736 -2.263  22.906  1   53.28  ? 185 TYR D OH  1 
ATOM   6989 N  N   . LEU D 2 16  ? -48.475 -6.622  22.767  1   51.54  ? 186 LEU D N   1 
ATOM   6990 C  CA  . LEU D 2 16  ? -48.069 -7.726  23.625  1   52.78  ? 186 LEU D CA  1 
ATOM   6991 C  C   . LEU D 2 16  ? -47.734 -8.96   22.778  1   56.32  ? 186 LEU D C   1 
ATOM   6992 O  O   . LEU D 2 16  ? -46.704 -9.606  22.987  1   53.27  ? 186 LEU D O   1 
ATOM   6993 C  CB  . LEU D 2 16  ? -49.146 -8.016  24.672  1   53.66  ? 186 LEU D CB  1 
ATOM   6994 C  CG  . LEU D 2 16  ? -49.199 -7.038  25.848  1   54.52  ? 186 LEU D CG  1 
ATOM   6995 C  CD1 . LEU D 2 16  ? -49.93  -7.66   27.03   1   58.47  ? 186 LEU D CD1 1 
ATOM   6996 C  CD2 . LEU D 2 16  ? -47.782 -6.673  26.272  1   52.11  ? 186 LEU D CD2 1 
ATOM   6997 N  N   . ARG D 2 17  ? -48.666 -9.184  21.772  1   58.92  ? 187 ARG D N   1 
ATOM   6998 C  CA  . ARG D 2 17  ? -48.466 -10.318 20.846  1   61.84  ? 187 ARG D CA  1 
ATOM   6999 C  C   . ARG D 2 17  ? -47.093 -10.207 20.177  1   62.36  ? 187 ARG D C   1 
ATOM   7000 O  O   . ARG D 2 17  ? -46.436 -11.245 20.021  1   65.91  ? 187 ARG D O   1 
ATOM   7001 C  CB  . ARG D 2 17  ? -49.582 -10.329 19.803  1   67.38  ? 187 ARG D CB  1 
ATOM   7002 C  CG  . ARG D 2 17  ? -50.896 -10.867 20.339  1   68.34  ? 187 ARG D CG  1 
ATOM   7003 C  CD  . ARG D 2 17  ? -50.734 -12.341 20.612  1   69.89  ? 187 ARG D CD  1 
ATOM   7004 N  NE  . ARG D 2 17  ? -51.808 -12.811 21.486  1   70.39  ? 187 ARG D NE  1 
ATOM   7005 C  CZ  . ARG D 2 17  ? -52.741 -13.661 21.108  1   69.47  ? 187 ARG D CZ  1 
ATOM   7006 N  NH1 . ARG D 2 17  ? -52.856 -13.986 19.834  1   74.07  ? 187 ARG D NH1 1 
ATOM   7007 N  NH2 . ARG D 2 17  ? -53.545 -14.181 22.016  1   67.96  ? 187 ARG D NH2 1 
ATOM   7008 N  N   . GLU D 2 18  ? -46.641 -9.053  19.842  1   59.54  ? 188 GLU D N   1 
ATOM   7009 C  CA  . GLU D 2 18  ? -45.402 -8.919  19.036  1   63.04  ? 188 GLU D CA  1 
ATOM   7010 C  C   . GLU D 2 18  ? -44.193 -8.899  19.971  1   63.98  ? 188 GLU D C   1 
ATOM   7011 O  O   . GLU D 2 18  ? -43.086 -9.209  19.508  1   71.46  ? 188 GLU D O   1 
ATOM   7012 C  CB  . GLU D 2 18  ? -45.437 -7.688  18.136  1   70.51  ? 188 GLU D CB  1 
ATOM   7013 C  CG  . GLU D 2 18  ? -44.997 -6.39   18.801  1   88.47  ? 188 GLU D CG  1 
ATOM   7014 C  CD  . GLU D 2 18  ? -45.278 -5.185  17.925  1   104.15 ? 188 GLU D CD  1 
ATOM   7015 O  OE1 . GLU D 2 18  ? -46.429 -5.051  17.462  1   106.02 ? 188 GLU D OE1 1 
ATOM   7016 O  OE2 . GLU D 2 18  ? -44.345 -4.386  17.701  1   104.88 ? 188 GLU D OE2 1 
ATOM   7017 N  N   . MET D 2 19  ? -44.417 -8.58   21.241  1   60.35  ? 189 MET D N   1 
ATOM   7018 C  CA  . MET D 2 19  ? -43.289 -8.474  22.195  1   58.7   ? 189 MET D CA  1 
ATOM   7019 C  C   . MET D 2 19  ? -43.002 -9.864  22.769  1   60.53  ? 189 MET D C   1 
ATOM   7020 O  O   . MET D 2 19  ? -41.844 -10.136 23.106  1   60.87  ? 189 MET D O   1 
ATOM   7021 C  CB  . MET D 2 19  ? -43.62  -7.453  23.287  1   55.24  ? 189 MET D CB  1 
ATOM   7022 C  CG  . MET D 2 19  ? -43.544 -6.024  22.816  1   55.74  ? 189 MET D CG  1 
ATOM   7023 S  SD  . MET D 2 19  ? -41.859 -5.504  22.445  1   57.29  ? 189 MET D SD  1 
ATOM   7024 C  CE  . MET D 2 19  ? -41.893 -5.439  20.65   1   56.79  ? 189 MET D CE  1 
ATOM   7025 N  N   . GLU D 2 20  ? -44.018 -10.72  22.819  1   59.89  ? 190 GLU D N   1 
ATOM   7026 C  CA  . GLU D 2 20  ? -43.851 -12.086 23.371  1   56.18  ? 190 GLU D CA  1 
ATOM   7027 C  C   . GLU D 2 20  ? -42.956 -12.927 22.447  1   53.5   ? 190 GLU D C   1 
ATOM   7028 O  O   . GLU D 2 20  ? -42.4   -13.92  22.922  1   49.81  ? 190 GLU D O   1 
ATOM   7029 C  CB  . GLU D 2 20  ? -45.242 -12.67  23.605  1   58.23  ? 190 GLU D CB  1 
ATOM   7030 C  CG  . GLU D 2 20  ? -45.805 -13.464 22.434  1   56.44  ? 190 GLU D CG  1 
ATOM   7031 C  CD  . GLU D 2 20  ? -47.113 -14.125 22.813  1   55.12  ? 190 GLU D CD  1 
ATOM   7032 O  OE1 . GLU D 2 20  ? -47.276 -14.487 23.991  1   51.96  ? 190 GLU D OE1 1 
ATOM   7033 O  OE2 . GLU D 2 20  ? -47.972 -14.272 21.929  1   55.15  ? 190 GLU D OE2 1 
ATOM   7034 N  N   . VAL D 2 21  ? -42.804 -12.517 21.194  1   54.98  ? 191 VAL D N   1 
ATOM   7035 C  CA  . VAL D 2 21  ? -41.96  -13.27  20.224  1   57.76  ? 191 VAL D CA  1 
ATOM   7036 C  C   . VAL D 2 21  ? -40.52  -12.764 20.357  1   57.65  ? 191 VAL D C   1 
ATOM   7037 O  O   . VAL D 2 21  ? -39.592 -13.527 20.059  1   54.61  ? 191 VAL D O   1 
ATOM   7038 C  CB  . VAL D 2 21  ? -42.504 -13.113 18.789  1   57.36  ? 191 VAL D CB  1 
ATOM   7039 C  CG1 . VAL D 2 21  ? -41.825 -14.054 17.804  1   53.96  ? 191 VAL D CG1 1 
ATOM   7040 C  CG2 . VAL D 2 21  ? -44.014 -13.296 18.739  1   54.07  ? 191 VAL D CG2 1 
ATOM   7041 N  N   . LYS D 2 22  ? -40.436 -11.454 20.824  1   64.2   ? 192 LYS D N   1 
ATOM   7042 C  CA  . LYS D 2 22  ? -39.102 -10.843 21.048  1   67.29  ? 192 LYS D CA  1 
ATOM   7043 C  C   . LYS D 2 22  ? -38.51  -11.395 22.35   1   61.41  ? 192 LYS D C   1 
ATOM   7044 O  O   . LYS D 2 22  ? -37.316 -11.74  22.354  1   57.99  ? 192 LYS D O   1 
ATOM   7045 C  CB  . LYS D 2 22  ? -39.226 -9.318  21.079  1   74.2   ? 192 LYS D CB  1 
ATOM   7046 C  CG  . LYS D 2 22  ? -38.154 -8.568  21.853  1   81.05  ? 192 LYS D CG  1 
ATOM   7047 C  CD  . LYS D 2 22  ? -38.718 -7.386  22.629  1   84.17  ? 192 LYS D CD  1 
ATOM   7048 C  CE  . LYS D 2 22  ? -37.721 -6.775  23.556  1   85.81  ? 192 LYS D CE  1 
ATOM   7049 N  NZ  . LYS D 2 22  ? -38.38  -6.039  24.637  1   82.09  ? 192 LYS D NZ  1 
ATOM   7050 N  N   . CYS D 2 23  ? -39.287 -11.535 23.365  1   55.27  ? 193 CYS D N   1 
ATOM   7051 C  CA  . CYS D 2 23  ? -38.832 -11.987 24.701  1   55.25  ? 193 CYS D CA  1 
ATOM   7052 C  C   . CYS D 2 23  ? -38.97  -13.511 24.796  1   57.75  ? 193 CYS D C   1 
ATOM   7053 O  O   . CYS D 2 23  ? -39.03  -14.021 25.923  1   59.96  ? 193 CYS D O   1 
ATOM   7054 C  CB  . CYS D 2 23  ? -39.632 -11.31  25.807  1   54.08  ? 193 CYS D CB  1 
ATOM   7055 S  SG  . CYS D 2 23  ? -39.753 -9.512  25.646  1   61.94  ? 193 CYS D SG  1 
ATOM   7056 N  N   . LYS D 2 24  ? -39.029 -14.199 23.654  1   54.75  ? 194 LYS D N   1 
ATOM   7057 C  CA  . LYS D 2 24  ? -39.183 -15.674 23.65   1   55.37  ? 194 LYS D CA  1 
ATOM   7058 C  C   . LYS D 2 24  ? -37.796 -16.32  23.71   1   56.78  ? 194 LYS D C   1 
ATOM   7059 O  O   . LYS D 2 24  ? -36.968 -16.04  22.829  1   55.55  ? 194 LYS D O   1 
ATOM   7060 C  CB  . LYS D 2 24  ? -39.972 -16.188 22.443  1   55.93  ? 194 LYS D CB  1 
ATOM   7061 C  CG  . LYS D 2 24  ? -40.234 -17.682 22.404  1   57.04  ? 194 LYS D CG  1 
ATOM   7062 C  CD  . LYS D 2 24  ? -41.063 -18.122 21.205  1   68.15  ? 194 LYS D CD  1 
ATOM   7063 C  CE  . LYS D 2 24  ? -41.294 -19.602 21.165  1   69.15  ? 194 LYS D CE  1 
ATOM   7064 N  NZ  . LYS D 2 24  ? -42.091 -20.039 20.017  1   69.13  ? 194 LYS D NZ  1 
ATOM   7065 N  N   . PRO D 2 25  ? -37.527 -17.168 24.726  1   54.09  ? 195 PRO D N   1 
ATOM   7066 C  CA  . PRO D 2 25  ? -36.24  -17.836 24.842  1   48.77  ? 195 PRO D CA  1 
ATOM   7067 C  C   . PRO D 2 25  ? -36.025 -18.879 23.774  1   52.71  ? 195 PRO D C   1 
ATOM   7068 O  O   . PRO D 2 25  ? -37.008 -19.374 23.213  1   55.62  ? 195 PRO D O   1 
ATOM   7069 C  CB  . PRO D 2 25  ? -36.34  -18.445 26.207  1   47.64  ? 195 PRO D CB  1 
ATOM   7070 C  CG  . PRO D 2 25  ? -37.405 -17.643 26.903  1   48.94  ? 195 PRO D CG  1 
ATOM   7071 C  CD  . PRO D 2 25  ? -38.43  -17.445 25.821  1   48.59  ? 195 PRO D CD  1 
ATOM   7072 N  N   . LYS D 2 26  ? -34.772 -19.236 23.517  1   53.89  ? 196 LYS D N   1 
ATOM   7073 C  CA  . LYS D 2 26  ? -34.507 -20.312 22.565  1   57.25  ? 196 LYS D CA  1 
ATOM   7074 C  C   . LYS D 2 26  ? -35.069 -21.629 23.106  1   55.86  ? 196 LYS D C   1 
ATOM   7075 O  O   . LYS D 2 26  ? -34.623 -22.084 24.155  1   52.27  ? 196 LYS D O   1 
ATOM   7076 C  CB  . LYS D 2 26  ? -33.004 -20.482 22.304  1   60.37  ? 196 LYS D CB  1 
ATOM   7077 C  CG  . LYS D 2 26  ? -32.245 -19.268 21.764  1   71.17  ? 196 LYS D CG  1 
ATOM   7078 C  CD  . LYS D 2 26  ? -30.853 -19.698 21.308  1   80.99  ? 196 LYS D CD  1 
ATOM   7079 C  CE  . LYS D 2 26  ? -29.737 -18.698 21.442  1   79.14  ? 196 LYS D CE  1 
ATOM   7080 N  NZ  . LYS D 2 26  ? -28.463 -19.427 21.392  1   73.96  ? 196 LYS D NZ  1 
ATOM   7081 N  N   . VAL D 2 27  ? -36.027 -22.249 22.388  1   59.35  ? 197 VAL D N   1 
ATOM   7082 C  CA  . VAL D 2 27  ? -36.582 -23.543 22.789  1   59.72  ? 197 VAL D CA  1 
ATOM   7083 C  C   . VAL D 2 27  ? -35.448 -24.568 22.859  1   57.88  ? 197 VAL D C   1 
ATOM   7084 O  O   . VAL D 2 27  ? -34.562 -24.565 22.012  1   55.78  ? 197 VAL D O   1 
ATOM   7085 C  CB  . VAL D 2 27  ? -37.747 -24.081 21.926  1   62.3   ? 197 VAL D CB  1 
ATOM   7086 C  CG1 . VAL D 2 27  ? -38.698 -22.972 21.474  1   59.42  ? 197 VAL D CG1 1 
ATOM   7087 C  CG2 . VAL D 2 27  ? -37.27  -24.921 20.744  1   62.38  ? 197 VAL D CG2 1 
ATOM   7088 N  N   . GLY D 2 28  ? -35.465 -25.426 23.884  1   61.41  ? 198 GLY D N   1 
ATOM   7089 C  CA  . GLY D 2 28  ? -34.384 -26.39  24.068  1   67.46  ? 198 GLY D CA  1 
ATOM   7090 C  C   . GLY D 2 28  ? -32.998 -25.731 24.085  1   67.21  ? 198 GLY D C   1 
ATOM   7091 O  O   . GLY D 2 28  ? -32.096 -26.106 23.336  1   71.56  ? 198 GLY D O   1 
ATOM   7092 N  N   . TYR D 2 29  ? -32.838 -24.716 24.937  1   57.83  ? 199 TYR D N   1 
ATOM   7093 C  CA  . TYR D 2 29  ? -31.526 -24.179 25.236  1   48.72  ? 199 TYR D CA  1 
ATOM   7094 C  C   . TYR D 2 29  ? -30.832 -25.129 26.206  1   48.33  ? 199 TYR D C   1 
ATOM   7095 O  O   . TYR D 2 29  ? -29.622 -25.091 26.323  1   50.05  ? 199 TYR D O   1 
ATOM   7096 C  CB  . TYR D 2 29  ? -31.611 -22.771 25.836  1   42.58  ? 199 TYR D CB  1 
ATOM   7097 C  CG  . TYR D 2 29  ? -32.296 -22.651 27.195  1   37.58  ? 199 TYR D CG  1 
ATOM   7098 C  CD1 . TYR D 2 29  ? -31.647 -23.02  28.378  1   36.61  ? 199 TYR D CD1 1 
ATOM   7099 C  CD2 . TYR D 2 29  ? -33.578 -22.135 27.309  1   34.6   ? 199 TYR D CD2 1 
ATOM   7100 C  CE1 . TYR D 2 29  ? -32.253 -22.882 29.618  1   33.68  ? 199 TYR D CE1 1 
ATOM   7101 C  CE2 . TYR D 2 29  ? -34.193 -21.986 28.542  1   33.88  ? 199 TYR D CE2 1 
ATOM   7102 C  CZ  . TYR D 2 29  ? -33.534 -22.367 29.699  1   34.95  ? 199 TYR D CZ  1 
ATOM   7103 O  OH  . TYR D 2 29  ? -34.172 -22.235 30.901  1   36.19  ? 199 TYR D OH  1 
ATOM   7104 N  N   . MET D 2 30  ? -31.587 -25.966 26.913  1   46.57  ? 200 MET D N   1 
ATOM   7105 C  CA  . MET D 2 30  ? -30.981 -26.814 27.971  1   48.69  ? 200 MET D CA  1 
ATOM   7106 C  C   . MET D 2 30  ? -30.032 -27.85  27.36   1   50.59  ? 200 MET D C   1 
ATOM   7107 O  O   . MET D 2 30  ? -29.179 -28.365 28.086  1   49.28  ? 200 MET D O   1 
ATOM   7108 C  CB  . MET D 2 30  ? -32.057 -27.529 28.792  1   50.27  ? 200 MET D CB  1 
ATOM   7109 C  CG  . MET D 2 30  ? -32.446 -26.816 30.058  1   52.63  ? 200 MET D CG  1 
ATOM   7110 S  SD  . MET D 2 30  ? -30.979 -26.433 31.026  1   52.04  ? 200 MET D SD  1 
ATOM   7111 C  CE  . MET D 2 30  ? -31.777 -25.531 32.358  1   54.59  ? 200 MET D CE  1 
ATOM   7112 N  N   . LYS D 2 31  ? -30.183 -28.127 26.073  1   54.08  ? 201 LYS D N   1 
ATOM   7113 C  CA  . LYS D 2 31  ? -29.333 -29.145 25.41   1   59.02  ? 201 LYS D CA  1 
ATOM   7114 C  C   . LYS D 2 31  ? -27.969 -28.532 25.086  1   57.14  ? 201 LYS D C   1 
ATOM   7115 O  O   . LYS D 2 31  ? -27.016 -29.296 24.888  1   62.13  ? 201 LYS D O   1 
ATOM   7116 C  CB  . LYS D 2 31  ? -30.039 -29.673 24.16   1   67.01  ? 201 LYS D CB  1 
ATOM   7117 C  CG  . LYS D 2 31  ? -31.285 -30.495 24.444  1   75.42  ? 201 LYS D CG  1 
ATOM   7118 C  CD  . LYS D 2 31  ? -31.844 -31.188 23.209  1   85.17  ? 201 LYS D CD  1 
ATOM   7119 C  CE  . LYS D 2 31  ? -32.402 -30.216 22.223  1   80.38  ? 201 LYS D CE  1 
ATOM   7120 N  NZ  . LYS D 2 31  ? -33.041 -30.898 21.097  1   86.56  ? 201 LYS D NZ  1 
ATOM   7121 N  N   . LYS D 2 32  ? -27.889 -27.207 25.045  1   52.67  ? 202 LYS D N   1 
ATOM   7122 C  CA  . LYS D 2 32  ? -26.593 -26.531 24.805  1   52.71  ? 202 LYS D CA  1 
ATOM   7123 C  C   . LYS D 2 32  ? -25.973 -26.184 26.161  1   49.39  ? 202 LYS D C   1 
ATOM   7124 O  O   . LYS D 2 32  ? -24.817 -25.749 26.178  1   48.61  ? 202 LYS D O   1 
ATOM   7125 C  CB  . LYS D 2 32  ? -26.847 -25.328 23.899  1   55.59  ? 202 LYS D CB  1 
ATOM   7126 C  CG  . LYS D 2 32  ? -27.288 -25.669 22.486  1   59.9   ? 202 LYS D CG  1 
ATOM   7127 C  CD  . LYS D 2 32  ? -27.55  -24.434 21.635  1   63.71  ? 202 LYS D CD  1 
ATOM   7128 C  CE  . LYS D 2 32  ? -27.959 -24.785 20.241  1   71.66  ? 202 LYS D CE  1 
ATOM   7129 N  NZ  . LYS D 2 32  ? -28.233 -23.595 19.432  1   75.84  ? 202 LYS D NZ  1 
ATOM   7130 N  N   . GLN D 2 33  ? -26.722 -26.392 27.242  1   45.24  ? 203 GLN D N   1 
ATOM   7131 C  CA  . GLN D 2 33  ? -26.199 -26.166 28.61   1   41.58  ? 203 GLN D CA  1 
ATOM   7132 C  C   . GLN D 2 33  ? -25.491 -27.447 29.052  1   44.32  ? 203 GLN D C   1 
ATOM   7133 O  O   . GLN D 2 33  ? -26.174 -28.448 29.263  1   43.63  ? 203 GLN D O   1 
ATOM   7134 C  CB  . GLN D 2 33  ? -27.327 -25.747 29.552  1   37.22  ? 203 GLN D CB  1 
ATOM   7135 C  CG  . GLN D 2 33  ? -27.848 -24.333 29.325  1   34.68  ? 203 GLN D CG  1 
ATOM   7136 C  CD  . GLN D 2 33  ? -27.029 -23.264 30.014  1   36.01  ? 203 GLN D CD  1 
ATOM   7137 O  OE1 . GLN D 2 33  ? -26.085 -23.545 30.758  1   37.9   ? 203 GLN D OE1 1 
ATOM   7138 N  NE2 . GLN D 2 33  ? -27.382 -22.014 29.763  1   33.49  ? 203 GLN D NE2 1 
ATOM   7139 N  N   . PRO D 2 34  ? -24.155 -27.452 29.214  1   47.48  ? 204 PRO D N   1 
ATOM   7140 C  CA  . PRO D 2 34  ? -23.427 -28.694 29.507  1   48.05  ? 204 PRO D CA  1 
ATOM   7141 C  C   . PRO D 2 34  ? -23.688 -29.177 30.932  1   47.39  ? 204 PRO D C   1 
ATOM   7142 O  O   . PRO D 2 34  ? -23.627 -30.368 31.199  1   50.34  ? 204 PRO D O   1 
ATOM   7143 C  CB  . PRO D 2 34  ? -21.949 -28.354 29.25   1   46.81  ? 204 PRO D CB  1 
ATOM   7144 C  CG  . PRO D 2 34  ? -21.993 -26.964 28.627  1   49.09  ? 204 PRO D CG  1 
ATOM   7145 C  CD  . PRO D 2 34  ? -23.265 -26.273 29.128  1   45.09  ? 204 PRO D CD  1 
ATOM   7146 N  N   . ASP D 2 35  ? -24.055 -28.264 31.829  1   45.12  ? 205 ASP D N   1 
ATOM   7147 C  CA  . ASP D 2 35  ? -24.025 -28.657 33.216  1   47.58  ? 205 ASP D CA  1 
ATOM   7148 C  C   . ASP D 2 35  ? -25.399 -28.712 33.864  1   46.67  ? 205 ASP D C   1 
ATOM   7149 O  O   . ASP D 2 35  ? -25.539 -29.392 34.859  1   54.71  ? 205 ASP D O   1 
ATOM   7150 C  CB  . ASP D 2 35  ? -23.107 -27.776 34.027  1   52.08  ? 205 ASP D CB  1 
ATOM   7151 C  CG  . ASP D 2 35  ? -22.613 -28.465 35.283  1   58.89  ? 205 ASP D CG  1 
ATOM   7152 O  OD1 . ASP D 2 35  ? -22.231 -29.675 35.167  1   66.68  ? 205 ASP D OD1 1 
ATOM   7153 O  OD2 . ASP D 2 35  ? -22.627 -27.794 36.341  1   52.4   ? 205 ASP D OD2 1 
ATOM   7154 N  N   . ILE D 2 36  ? -26.396 -28.012 33.327  1   43.74  ? 206 ILE D N   1 
ATOM   7155 C  CA  . ILE D 2 36  ? -27.711 -27.992 33.939  1   39.48  ? 206 ILE D CA  1 
ATOM   7156 C  C   . ILE D 2 36  ? -28.734 -28.656 33.009  1   42.99  ? 206 ILE D C   1 
ATOM   7157 O  O   . ILE D 2 36  ? -28.457 -28.859 31.82   1   44.06  ? 206 ILE D O   1 
ATOM   7158 C  CB  . ILE D 2 36  ? -28.095 -26.559 34.336  1   36.29  ? 206 ILE D CB  1 
ATOM   7159 C  CG1 . ILE D 2 36  ? -28.016 -25.606 33.175  1   36.21  ? 206 ILE D CG1 1 
ATOM   7160 C  CG2 . ILE D 2 36  ? -27.239 -26.05  35.499  1   35.24  ? 206 ILE D CG2 1 
ATOM   7161 C  CD1 . ILE D 2 36  ? -28.547 -24.221 33.51   1   36.54  ? 206 ILE D CD1 1 
ATOM   7162 N  N   . THR D 2 37  ? -29.914 -28.998 33.571  1   40.84  ? 207 THR D N   1 
ATOM   7163 C  CA  . THR D 2 37  ? -30.946 -29.784 32.898  1   41.46  ? 207 THR D CA  1 
ATOM   7164 C  C   . THR D 2 37  ? -32.322 -29.211 33.223  1   41.59  ? 207 THR D C   1 
ATOM   7165 O  O   . THR D 2 37  ? -32.436 -28.416 34.155  1   42.47  ? 207 THR D O   1 
ATOM   7166 C  CB  . THR D 2 37  ? -30.88  -31.242 33.363  1   39.68  ? 207 THR D CB  1 
ATOM   7167 O  OG1 . THR D 2 37  ? -31.244 -31.171 34.741  1   40.64  ? 207 THR D OG1 1 
ATOM   7168 C  CG2 . THR D 2 37  ? -29.51  -31.857 33.163  1   37.3   ? 207 THR D CG2 1 
ATOM   7169 N  N   . ASN D 2 38  ? -33.373 -29.691 32.528  1   43.69  ? 208 ASN D N   1 
ATOM   7170 C  CA  . ASN D 2 38  ? -34.732 -29.205 32.776  1   41.98  ? 208 ASN D CA  1 
ATOM   7171 C  C   . ASN D 2 38  ? -35.163 -29.528 34.206  1   39.87  ? 208 ASN D C   1 
ATOM   7172 O  O   . ASN D 2 38  ? -35.918 -28.77  34.813  1   38.79  ? 208 ASN D O   1 
ATOM   7173 C  CB  . ASN D 2 38  ? -35.781 -29.785 31.836  1   43.57  ? 208 ASN D CB  1 
ATOM   7174 C  CG  . ASN D 2 38  ? -35.52  -29.498 30.377  1   45.75  ? 208 ASN D CG  1 
ATOM   7175 O  OD1 . ASN D 2 38  ? -35.472 -28.34  29.957  1   43.72  ? 208 ASN D OD1 1 
ATOM   7176 N  ND2 . ASN D 2 38  ? -35.427 -30.557 29.584  1   48.81  ? 208 ASN D ND2 1 
ATOM   7177 N  N   . SER D 2 39  ? -34.661 -30.652 34.728  1   39.54  ? 209 SER D N   1 
ATOM   7178 C  CA  . SER D 2 39  ? -34.977 -31.106 36.068  1   39.48  ? 209 SER D CA  1 
ATOM   7179 C  C   . SER D 2 39  ? -34.503 -30.091 37.109  1   39.45  ? 209 SER D C   1 
ATOM   7180 O  O   . SER D 2 39  ? -35.216 -29.775 38.066  1   38.43  ? 209 SER D O   1 
ATOM   7181 C  CB  . SER D 2 39  ? -34.353 -32.435 36.318  1   40.21  ? 209 SER D CB  1 
ATOM   7182 O  OG  . SER D 2 39  ? -34.631 -32.8   37.659  1   42.78  ? 209 SER D OG  1 
ATOM   7183 N  N   . MET D 2 40  ? -33.27  -29.605 36.92   1   40.06  ? 210 MET D N   1 
ATOM   7184 C  CA  . MET D 2 40  ? -32.703 -28.577 37.781  1   39.37  ? 210 MET D CA  1 
ATOM   7185 C  C   . MET D 2 40  ? -33.555 -27.31  37.628  1   40.01  ? 210 MET D C   1 
ATOM   7186 O  O   . MET D 2 40  ? -33.919 -26.669 38.617  1   35.83  ? 210 MET D O   1 
ATOM   7187 C  CB  . MET D 2 40  ? -31.221 -28.328 37.461  1   36.25  ? 210 MET D CB  1 
ATOM   7188 C  CG  . MET D 2 40  ? -30.349 -29.547 37.609  1   37.63  ? 210 MET D CG  1 
ATOM   7189 S  SD  . MET D 2 40  ? -28.625 -29.188 37.22   1   41.58  ? 210 MET D SD  1 
ATOM   7190 C  CE  . MET D 2 40  ? -27.936 -30.824 36.897  1   36.1   ? 210 MET D CE  1 
ATOM   7191 N  N   . ARG D 2 41  ? -33.938 -26.996 36.382  1   38.61  ? 211 ARG D N   1 
ATOM   7192 C  CA  . ARG D 2 41  ? -34.687 -25.772 36.161  1   38.75  ? 211 ARG D CA  1 
ATOM   7193 C  C   . ARG D 2 41  ? -36.005 -25.865 36.926  1   38.76  ? 211 ARG D C   1 
ATOM   7194 O  O   . ARG D 2 41  ? -36.454 -24.87  37.493  1   36.96  ? 211 ARG D O   1 
ATOM   7195 C  CB  . ARG D 2 41  ? -34.857 -25.484 34.667  1   37.7   ? 211 ARG D CB  1 
ATOM   7196 C  CG  . ARG D 2 41  ? -35.721 -24.266 34.384  1   36.44  ? 211 ARG D CG  1 
ATOM   7197 C  CD  . ARG D 2 41  ? -36.042 -24.148 32.902  1   39.41  ? 211 ARG D CD  1 
ATOM   7198 N  NE  . ARG D 2 41  ? -37.075 -23.146 32.614  1   40.66  ? 211 ARG D NE  1 
ATOM   7199 C  CZ  . ARG D 2 41  ? -38.353 -23.241 32.981  1   41.89  ? 211 ARG D CZ  1 
ATOM   7200 N  NH1 . ARG D 2 41  ? -38.83  -24.353 33.533  1   43.42  ? 211 ARG D NH1 1 
ATOM   7201 N  NH2 . ARG D 2 41  ? -39.151 -22.213 32.772  1   39.36  ? 211 ARG D NH2 1 
ATOM   7202 N  N   . ALA D 2 42  ? -36.592 -27.073 36.925  1   40.56  ? 212 ALA D N   1 
ATOM   7203 C  CA  . ALA D 2 42  ? -37.852 -27.366 37.595  1   41.61  ? 212 ALA D CA  1 
ATOM   7204 C  C   . ALA D 2 42  ? -37.744 -27.039 39.082  1   41.82  ? 212 ALA D C   1 
ATOM   7205 O  O   . ALA D 2 42  ? -38.604 -26.34  39.627  1   41.35  ? 212 ALA D O   1 
ATOM   7206 C  CB  . ALA D 2 42  ? -38.264 -28.806 37.37   1   39.1   ? 212 ALA D CB  1 
ATOM   7207 N  N   . ILE D 2 43  ? -36.652 -27.514 39.704  1   41.51  ? 213 ILE D N   1 
ATOM   7208 C  CA  . ILE D 2 43  ? -36.363 -27.225 41.099  1   40.99  ? 213 ILE D CA  1 
ATOM   7209 C  C   . ILE D 2 43  ? -36.295 -25.721 41.362  1   40.53  ? 213 ILE D C   1 
ATOM   7210 O  O   . ILE D 2 43  ? -36.793 -25.246 42.372  1   44.47  ? 213 ILE D O   1 
ATOM   7211 C  CB  . ILE D 2 43  ? -35.047 -27.893 41.514  1   39.73  ? 213 ILE D CB  1 
ATOM   7212 C  CG1 . ILE D 2 43  ? -35.211 -29.405 41.606  1   37.91  ? 213 ILE D CG1 1 
ATOM   7213 C  CG2 . ILE D 2 43  ? -34.565 -27.281 42.837  1   38.37  ? 213 ILE D CG2 1 
ATOM   7214 C  CD1 . ILE D 2 43  ? -33.892 -30.158 41.528  1   38.28  ? 213 ILE D CD1 1 
ATOM   7215 N  N   . LEU D 2 44  ? -35.606 -24.993 40.482  1   41.16  ? 214 LEU D N   1 
ATOM   7216 C  CA  . LEU D 2 44  ? -35.399 -23.562 40.589  1   40.23  ? 214 LEU D CA  1 
ATOM   7217 C  C   . LEU D 2 44  ? -36.739 -22.825 40.529  1   40.13  ? 214 LEU D C   1 
ATOM   7218 O  O   . LEU D 2 44  ? -36.998 -21.93  41.342  1   42.06  ? 214 LEU D O   1 
ATOM   7219 C  CB  . LEU D 2 44  ? -34.412 -23.054 39.534  1   39.31  ? 214 LEU D CB  1 
ATOM   7220 C  CG  . LEU D 2 44  ? -34.289 -21.526 39.454  1   39.94  ? 214 LEU D CG  1 
ATOM   7221 C  CD1 . LEU D 2 44  ? -33.748 -20.959 40.777  1   37.53  ? 214 LEU D CD1 1 
ATOM   7222 C  CD2 . LEU D 2 44  ? -33.465 -21.08  38.271  1   37.55  ? 214 LEU D CD2 1 
ATOM   7223 N  N   . VAL D 2 45  ? -37.594 -23.234 39.585  1   35.97  ? 215 VAL D N   1 
ATOM   7224 C  CA  . VAL D 2 45  ? -38.869 -22.56  39.418  1   36.97  ? 215 VAL D CA  1 
ATOM   7225 C  C   . VAL D 2 45  ? -39.807 -22.897 40.578  1   37.95  ? 215 VAL D C   1 
ATOM   7226 O  O   . VAL D 2 45  ? -40.543 -22.04  41.043  1   35.98  ? 215 VAL D O   1 
ATOM   7227 C  CB  . VAL D 2 45  ? -39.522 -22.784 38.043  1   38.07  ? 215 VAL D CB  1 
ATOM   7228 C  CG1 . VAL D 2 45  ? -40.888 -22.116 37.978  1   39.36  ? 215 VAL D CG1 1 
ATOM   7229 C  CG2 . VAL D 2 45  ? -38.619 -22.289 36.908  1   35.31  ? 215 VAL D CG2 1 
ATOM   7230 N  N   . ASP D 2 46  ? -39.774 -24.141 41.069  1   40.2   ? 216 ASP D N   1 
ATOM   7231 C  CA  . ASP D 2 46  ? -40.567 -24.453 42.245  1   41.67  ? 216 ASP D CA  1 
ATOM   7232 C  C   . ASP D 2 46  ? -40.085 -23.605 43.418  1   42.77  ? 216 ASP D C   1 
ATOM   7233 O  O   . ASP D 2 46  ? -40.886 -23.107 44.211  1   45.21  ? 216 ASP D O   1 
ATOM   7234 C  CB  . ASP D 2 46  ? -40.439 -25.906 42.655  1   42.98  ? 216 ASP D CB  1 
ATOM   7235 C  CG  . ASP D 2 46  ? -41.428 -26.358 43.721  1   45.74  ? 216 ASP D CG  1 
ATOM   7236 O  OD1 . ASP D 2 46  ? -42.575 -26.711 43.353  1   48.1   ? 216 ASP D OD1 1 
ATOM   7237 O  OD2 . ASP D 2 46  ? -41.055 -26.351 44.912  1   44.39  ? 216 ASP D OD2 1 
ATOM   7238 N  N   . TRP D 2 47  ? -38.763 -23.465 43.544  1   40.58  ? 217 TRP D N   1 
ATOM   7239 C  CA  . TRP D 2 47  ? -38.25  -22.665 44.637  1   41.67  ? 217 TRP D CA  1 
ATOM   7240 C  C   . TRP D 2 47  ? -38.751 -21.229 44.524  1   41.33  ? 217 TRP D C   1 
ATOM   7241 O  O   . TRP D 2 47  ? -39.141 -20.627 45.522  1   40.94  ? 217 TRP D O   1 
ATOM   7242 C  CB  . TRP D 2 47  ? -36.726 -22.684 44.657  1   41.16  ? 217 TRP D CB  1 
ATOM   7243 C  CG  . TRP D 2 47  ? -36.155 -21.792 45.725  1   41.57  ? 217 TRP D CG  1 
ATOM   7244 C  CD1 . TRP D 2 47  ? -36.294 -21.935 47.075  1   41.92  ? 217 TRP D CD1 1 
ATOM   7245 C  CD2 . TRP D 2 47  ? -35.303 -20.642 45.521  1   39     ? 217 TRP D CD2 1 
ATOM   7246 N  NE1 . TRP D 2 47  ? -35.596 -20.955 47.73   1   41.1   ? 217 TRP D NE1 1 
ATOM   7247 C  CE2 . TRP D 2 47  ? -34.961 -20.159 46.807  1   40.76  ? 217 TRP D CE2 1 
ATOM   7248 C  CE3 . TRP D 2 47  ? -34.8   -19.987 44.392  1   35.39  ? 217 TRP D CE3 1 
ATOM   7249 C  CZ2 . TRP D 2 47  ? -34.141 -19.04  46.985  1   39.71  ? 217 TRP D CZ2 1 
ATOM   7250 C  CZ3 . TRP D 2 47  ? -33.963 -18.909 44.568  1   35.52  ? 217 TRP D CZ3 1 
ATOM   7251 C  CH2 . TRP D 2 47  ? -33.636 -18.447 45.846  1   37.78  ? 217 TRP D CH2 1 
ATOM   7252 N  N   . LEU D 2 48  ? -38.756 -20.697 43.294  1   41.91  ? 218 LEU D N   1 
ATOM   7253 C  CA  . LEU D 2 48  ? -39.275 -19.351 43.072  1   42.48  ? 218 LEU D CA  1 
ATOM   7254 C  C   . LEU D 2 48  ? -40.723 -19.191 43.567  1   42.87  ? 218 LEU D C   1 
ATOM   7255 O  O   . LEU D 2 48  ? -41.056 -18.19  44.198  1   41.6   ? 218 LEU D O   1 
ATOM   7256 C  CB  . LEU D 2 48  ? -39.018 -18.885 41.641  1   38.68  ? 218 LEU D CB  1 
ATOM   7257 C  CG  . LEU D 2 48  ? -37.537 -18.668 41.298  1   39.34  ? 218 LEU D CG  1 
ATOM   7258 C  CD1 . LEU D 2 48  ? -37.437 -18.158 39.873  1   42.06  ? 218 LEU D CD1 1 
ATOM   7259 C  CD2 . LEU D 2 48  ? -36.81  -17.703 42.235  1   38.46  ? 218 LEU D CD2 1 
ATOM   7260 N  N   . VAL D 2 49  ? -41.565 -20.211 43.35   1   43.27  ? 219 VAL D N   1 
ATOM   7261 C  CA  . VAL D 2 49  ? -42.957 -20.159 43.773  1   44.16  ? 219 VAL D CA  1 
ATOM   7262 C  C   . VAL D 2 49  ? -43.041 -19.959 45.289  1   44.47  ? 219 VAL D C   1 
ATOM   7263 O  O   . VAL D 2 49  ? -43.766 -19.092 45.776  1   45.03  ? 219 VAL D O   1 
ATOM   7264 C  CB  . VAL D 2 49  ? -43.667 -21.442 43.299  1   43.93  ? 219 VAL D CB  1 
ATOM   7265 C  CG1 . VAL D 2 49  ? -45.054 -21.585 43.918  1   43.13  ? 219 VAL D CG1 1 
ATOM   7266 C  CG2 . VAL D 2 49  ? -43.706 -21.519 41.774  1   39.96  ? 219 VAL D CG2 1 
ATOM   7267 N  N   . GLU D 2 50  ? -42.264 -20.748 46.032  1   45.74  ? 220 GLU D N   1 
ATOM   7268 C  CA  . GLU D 2 50  ? -42.247 -20.654 47.483  1   49.01  ? 220 GLU D CA  1 
ATOM   7269 C  C   . GLU D 2 50  ? -41.823 -19.266 47.935  1   47.41  ? 220 GLU D C   1 
ATOM   7270 O  O   . GLU D 2 50  ? -42.394 -18.733 48.9    1   48.27  ? 220 GLU D O   1 
ATOM   7271 C  CB  . GLU D 2 50  ? -41.157 -21.534 48.072  1   50.27  ? 220 GLU D CB  1 
ATOM   7272 C  CG  . GLU D 2 50  ? -41.421 -22.99  47.737  1   60.13  ? 220 GLU D CG  1 
ATOM   7273 C  CD  . GLU D 2 50  ? -40.749 -23.861 48.761  1   69.55  ? 220 GLU D CD  1 
ATOM   7274 O  OE1 . GLU D 2 50  ? -41.428 -24.785 49.285  1   77.32  ? 220 GLU D OE1 1 
ATOM   7275 O  OE2 . GLU D 2 50  ? -39.564 -23.566 49.045  1   71.1   ? 220 GLU D OE2 1 
ATOM   7276 N  N   . VAL D 2 51  ? -40.784 -18.746 47.253  1   41.83  ? 221 VAL D N   1 
ATOM   7277 C  CA  . VAL D 2 51  ? -40.255 -17.414 47.503  1   39.8   ? 221 VAL D CA  1 
ATOM   7278 C  C   . VAL D 2 51  ? -41.37  -16.389 47.313  1   39.73  ? 221 VAL D C   1 
ATOM   7279 O  O   . VAL D 2 51  ? -41.639 -15.582 48.21   1   42.97  ? 221 VAL D O   1 
ATOM   7280 C  CB  . VAL D 2 51  ? -38.998 -17.053 46.693  1   37.23  ? 221 VAL D CB  1 
ATOM   7281 C  CG1 . VAL D 2 51  ? -38.727 -15.559 46.761  1   35.4   ? 221 VAL D CG1 1 
ATOM   7282 C  CG2 . VAL D 2 51  ? -37.786 -17.85  47.164  1   34.99  ? 221 VAL D CG2 1 
ATOM   7283 N  N   . GLY D 2 52  ? -42.038 -16.474 46.165  1   36.42  ? 222 GLY D N   1 
ATOM   7284 C  CA  . GLY D 2 52  ? -43.223 -15.692 45.895  1   38.27  ? 222 GLY D CA  1 
ATOM   7285 C  C   . GLY D 2 52  ? -44.197 -15.675 47.071  1   46.19  ? 222 GLY D C   1 
ATOM   7286 O  O   . GLY D 2 52  ? -44.615 -14.586 47.466  1   48.91  ? 222 GLY D O   1 
ATOM   7287 N  N   . GLU D 2 53  ? -44.55  -16.864 47.608  1   48.54  ? 223 GLU D N   1 
ATOM   7288 C  CA  . GLU D 2 53  ? -45.514 -17.008 48.696  1   52.14  ? 223 GLU D CA  1 
ATOM   7289 C  C   . GLU D 2 53  ? -44.953 -16.447 49.993  1   52.33  ? 223 GLU D C   1 
ATOM   7290 O  O   . GLU D 2 53  ? -45.644 -15.704 50.682  1   54.95  ? 223 GLU D O   1 
ATOM   7291 C  CB  . GLU D 2 53  ? -45.968 -18.441 49.002  1   58.27  ? 223 GLU D CB  1 
ATOM   7292 C  CG  . GLU D 2 53  ? -46.899 -19.022 47.942  1   68.23  ? 223 GLU D CG  1 
ATOM   7293 C  CD  . GLU D 2 53  ? -47.904 -18.012 47.382  1   79.71  ? 223 GLU D CD  1 
ATOM   7294 O  OE1 . GLU D 2 53  ? -47.552 -17.425 46.318  1   76.38  ? 223 GLU D OE1 1 
ATOM   7295 O  OE2 . GLU D 2 53  ? -49.012 -17.806 47.967  1   81.04  ? 223 GLU D OE2 1 
ATOM   7296 N  N   . GLU D 2 54  ? -43.716 -16.831 50.335  1   51.79  ? 224 GLU D N   1 
ATOM   7297 C  CA  . GLU D 2 54  ? -43.093 -16.309 51.54   1   54.39  ? 224 GLU D CA  1 
ATOM   7298 C  C   . GLU D 2 54  ? -43.214 -14.786 51.572  1   51.95  ? 224 GLU D C   1 
ATOM   7299 O  O   . GLU D 2 54  ? -43.582 -14.238 52.599  1   51.77  ? 224 GLU D O   1 
ATOM   7300 C  CB  . GLU D 2 54  ? -41.632 -16.747 51.64   1   58.38  ? 224 GLU D CB  1 
ATOM   7301 C  CG  . GLU D 2 54  ? -40.949 -16.311 52.932  1   64.74  ? 224 GLU D CG  1 
ATOM   7302 C  CD  . GLU D 2 54  ? -41.465 -16.986 54.189  1   77.66  ? 224 GLU D CD  1 
ATOM   7303 O  OE1 . GLU D 2 54  ? -42.422 -17.793 54.081  1   82.53  ? 224 GLU D OE1 1 
ATOM   7304 O  OE2 . GLU D 2 54  ? -40.915 -16.693 55.277  1   82.97  ? 224 GLU D OE2 1 
ATOM   7305 N  N   . TYR D 2 55  ? -42.926 -14.119 50.444  1   48.66  ? 225 TYR D N   1 
ATOM   7306 C  CA  . TYR D 2 55  ? -42.828 -12.669 50.43   1   50.01  ? 225 TYR D CA  1 
ATOM   7307 C  C   . TYR D 2 55  ? -44.104 -12.002 49.926  1   51.7   ? 225 TYR D C   1 
ATOM   7308 O  O   . TYR D 2 55  ? -44.14  -10.774 49.844  1   52.46  ? 225 TYR D O   1 
ATOM   7309 C  CB  . TYR D 2 55  ? -41.586 -12.174 49.687  1   48.92  ? 225 TYR D CB  1 
ATOM   7310 C  CG  . TYR D 2 55  ? -40.346 -12.429 50.528  1   52.93  ? 225 TYR D CG  1 
ATOM   7311 C  CD1 . TYR D 2 55  ? -39.972 -11.55  51.547  1   52.53  ? 225 TYR D CD1 1 
ATOM   7312 C  CD2 . TYR D 2 55  ? -39.578 -13.575 50.343  1   51.25  ? 225 TYR D CD2 1 
ATOM   7313 C  CE1 . TYR D 2 55  ? -38.867 -11.798 52.344  1   50.73  ? 225 TYR D CE1 1 
ATOM   7314 C  CE2 . TYR D 2 55  ? -38.462 -13.815 51.125  1   50.24  ? 225 TYR D CE2 1 
ATOM   7315 C  CZ  . TYR D 2 55  ? -38.108 -12.93  52.124  1   50.58  ? 225 TYR D CZ  1 
ATOM   7316 O  OH  . TYR D 2 55  ? -37.004 -13.177 52.885  1   55.43  ? 225 TYR D OH  1 
ATOM   7317 N  N   . LYS D 2 56  ? -45.14  -12.809 49.638  1   53.91  ? 226 LYS D N   1 
ATOM   7318 C  CA  . LYS D 2 56  ? -46.448 -12.348 49.178  1   51.51  ? 226 LYS D CA  1 
ATOM   7319 C  C   . LYS D 2 56  ? -46.309 -11.505 47.909  1   47.75  ? 226 LYS D C   1 
ATOM   7320 O  O   . LYS D 2 56  ? -46.99  -10.512 47.758  1   50.32  ? 226 LYS D O   1 
ATOM   7321 C  CB  . LYS D 2 56  ? -47.241 -11.674 50.31   1   53.19  ? 226 LYS D CB  1 
ATOM   7322 C  CG  . LYS D 2 56  ? -47.681 -12.588 51.452  1   61.37  ? 226 LYS D CG  1 
ATOM   7323 C  CD  . LYS D 2 56  ? -48.452 -11.959 52.611  1   66.97  ? 226 LYS D CD  1 
ATOM   7324 C  CE  . LYS D 2 56  ? -48.865 -12.944 53.678  1   71.1   ? 226 LYS D CE  1 
ATOM   7325 N  NZ  . LYS D 2 56  ? -49.582 -12.296 54.786  1   70.38  ? 226 LYS D NZ  1 
ATOM   7326 N  N   . LEU D 2 57  ? -45.424 -11.895 46.991  1   44.37  ? 227 LEU D N   1 
ATOM   7327 C  CA  . LEU D 2 57  ? -45.25  -11.166 45.745  1   41.73  ? 227 LEU D CA  1 
ATOM   7328 C  C   . LEU D 2 57  ? -46.39  -11.477 44.78   1   43.02  ? 227 LEU D C   1 
ATOM   7329 O  O   . LEU D 2 57  ? -47.06  -12.511 44.88   1   44.63  ? 227 LEU D O   1 
ATOM   7330 C  CB  . LEU D 2 57  ? -43.934 -11.62  45.126  1   37.28  ? 227 LEU D CB  1 
ATOM   7331 C  CG  . LEU D 2 57  ? -42.753 -11.587 46.087  1   36.28  ? 227 LEU D CG  1 
ATOM   7332 C  CD1 . LEU D 2 57  ? -41.585 -12.137 45.319  1   34.26  ? 227 LEU D CD1 1 
ATOM   7333 C  CD2 . LEU D 2 57  ? -42.546 -10.182 46.646  1   33.62  ? 227 LEU D CD2 1 
ATOM   7334 N  N   . GLN D 2 58  ? -46.556 -10.579 43.813  1   41.38  ? 228 GLN D N   1 
ATOM   7335 C  CA  . GLN D 2 58  ? -47.499 -10.775 42.734  1   43.88  ? 228 GLN D CA  1 
ATOM   7336 C  C   . GLN D 2 58  ? -47.072 -11.977 41.907  1   46.6   ? 228 GLN D C   1 
ATOM   7337 O  O   . GLN D 2 58  ? -45.877 -12.234 41.761  1   46.02  ? 228 GLN D O   1 
ATOM   7338 C  CB  . GLN D 2 58  ? -47.403 -9.549  41.837  1   42.51  ? 228 GLN D CB  1 
ATOM   7339 C  CG  . GLN D 2 58  ? -47.862 -8.282  42.537  1   42.31  ? 228 GLN D CG  1 
ATOM   7340 C  CD  . GLN D 2 58  ? -49.3   -8.438  42.948  1   45.86  ? 228 GLN D CD  1 
ATOM   7341 O  OE1 . GLN D 2 58  ? -50.083 -9.02   42.196  1   52.56  ? 228 GLN D OE1 1 
ATOM   7342 N  NE2 . GLN D 2 58  ? -49.646 -8.022  44.152  1   44.9   ? 228 GLN D NE2 1 
ATOM   7343 N  N   . ASN D 2 59  ? -48.072 -12.69  41.369  1   50.93  ? 229 ASN D N   1 
ATOM   7344 C  CA  . ASN D 2 59  ? -47.865 -13.788 40.428  1   54.74  ? 229 ASN D CA  1 
ATOM   7345 C  C   . ASN D 2 59  ? -47.171 -13.281 39.159  1   49.42  ? 229 ASN D C   1 
ATOM   7346 O  O   . ASN D 2 59  ? -46.415 -14.009 38.501  1   46.85  ? 229 ASN D O   1 
ATOM   7347 C  CB  . ASN D 2 59  ? -49.164 -14.55  40.151  1   59.47  ? 229 ASN D CB  1 
ATOM   7348 C  CG  . ASN D 2 59  ? -49.654 -15.302 41.371  1   60.72  ? 229 ASN D CG  1 
ATOM   7349 O  OD1 . ASN D 2 59  ? -48.868 -15.895 42.12   1   59.15  ? 229 ASN D OD1 1 
ATOM   7350 N  ND2 . ASN D 2 59  ? -50.951 -15.274 41.615  1   63.38  ? 229 ASN D ND2 1 
ATOM   7351 N  N   . GLU D 2 60  ? -47.421 -12.007 38.842  1   45.38  ? 230 GLU D N   1 
ATOM   7352 C  CA  . GLU D 2 60  ? -46.807 -11.379 37.689  1   44     ? 230 GLU D CA  1 
ATOM   7353 C  C   . GLU D 2 60  ? -45.292 -11.405 37.872  1   42.12  ? 230 GLU D C   1 
ATOM   7354 O  O   . GLU D 2 60  ? -44.548 -11.66  36.926  1   47.42  ? 230 GLU D O   1 
ATOM   7355 C  CB  . GLU D 2 60  ? -47.381 -9.973  37.471  1   42.28  ? 230 GLU D CB  1 
ATOM   7356 C  CG  . GLU D 2 60  ? -46.712 -9.242  36.309  1   42.7   ? 230 GLU D CG  1 
ATOM   7357 C  CD  . GLU D 2 60  ? -46.818 -9.832  34.905  1   43.18  ? 230 GLU D CD  1 
ATOM   7358 O  OE1 . GLU D 2 60  ? -47.649 -10.715 34.684  1   48.37  ? 230 GLU D OE1 1 
ATOM   7359 O  OE2 . GLU D 2 60  ? -46.073 -9.429  34.004  1   41.47  ? 230 GLU D OE2 1 
ATOM   7360 N  N   . THR D 2 61  ? -44.848 -11.123 39.1    1   39.56  ? 231 THR D N   1 
ATOM   7361 C  CA  . THR D 2 61  ? -43.433 -11.049 39.426  1   38.26  ? 231 THR D CA  1 
ATOM   7362 C  C   . THR D 2 61  ? -42.766 -12.4   39.184  1   40.74  ? 231 THR D C   1 
ATOM   7363 O  O   . THR D 2 61  ? -41.629 -12.437 38.713  1   39.66  ? 231 THR D O   1 
ATOM   7364 C  CB  . THR D 2 61  ? -43.277 -10.62  40.881  1   36.84  ? 231 THR D CB  1 
ATOM   7365 O  OG1 . THR D 2 61  ? -43.963 -9.38   40.915  1   34.98  ? 231 THR D OG1 1 
ATOM   7366 C  CG2 . THR D 2 61  ? -41.826 -10.445 41.298  1   37.81  ? 231 THR D CG2 1 
ATOM   7367 N  N   . LEU D 2 62  ? -43.479 -13.492 39.532  1   43.1   ? 232 LEU D N   1 
ATOM   7368 C  CA  . LEU D 2 62  ? -43.025 -14.859 39.317  1   40.51  ? 232 LEU D CA  1 
ATOM   7369 C  C   . LEU D 2 62  ? -42.831 -15.121 37.826  1   42.4   ? 232 LEU D C   1 
ATOM   7370 O  O   . LEU D 2 62  ? -41.788 -15.617 37.421  1   43.34  ? 232 LEU D O   1 
ATOM   7371 C  CB  . LEU D 2 62  ? -44.027 -15.845 39.909  1   43.71  ? 232 LEU D CB  1 
ATOM   7372 C  CG  . LEU D 2 62  ? -43.729 -17.331 39.664  1   44.36  ? 232 LEU D CG  1 
ATOM   7373 C  CD1 . LEU D 2 62  ? -42.374 -17.691 40.24   1   42.02  ? 232 LEU D CD1 1 
ATOM   7374 C  CD2 . LEU D 2 62  ? -44.772 -18.248 40.269  1   45.42  ? 232 LEU D CD2 1 
ATOM   7375 N  N   . HIS D 2 63  ? -43.849 -14.803 37.02   1   41.81  ? 233 HIS D N   1 
ATOM   7376 C  CA  . HIS D 2 63  ? -43.79  -15.124 35.609  1   42.08  ? 233 HIS D CA  1 
ATOM   7377 C  C   . HIS D 2 63  ? -42.629 -14.374 34.976  1   43.51  ? 233 HIS D C   1 
ATOM   7378 O  O   . HIS D 2 63  ? -41.946 -14.939 34.122  1   43.19  ? 233 HIS D O   1 
ATOM   7379 C  CB  . HIS D 2 63  ? -45.098 -14.773 34.889  1   42.47  ? 233 HIS D CB  1 
ATOM   7380 C  CG  . HIS D 2 63  ? -46.165 -15.787 35.046  1   40.1   ? 233 HIS D CG  1 
ATOM   7381 N  ND1 . HIS D 2 63  ? -46.813 -15.952 36.251  1   41.71  ? 233 HIS D ND1 1 
ATOM   7382 C  CD2 . HIS D 2 63  ? -46.698 -16.678 34.219  1   40.98  ? 233 HIS D CD2 1 
ATOM   7383 C  CE1 . HIS D 2 63  ? -47.709 -16.929 36.153  1   41.35  ? 233 HIS D CE1 1 
ATOM   7384 N  NE2 . HIS D 2 63  ? -47.647 -17.395 34.929  1   43.58  ? 233 HIS D NE2 1 
ATOM   7385 N  N   . LEU D 2 64  ? -42.429 -13.107 35.389  1   44.59  ? 234 LEU D N   1 
ATOM   7386 C  CA  . LEU D 2 64  ? -41.355 -12.261 34.868  1   40.79  ? 234 LEU D CA  1 
ATOM   7387 C  C   . LEU D 2 64  ? -39.994 -12.909 35.169  1   39.52  ? 234 LEU D C   1 
ATOM   7388 O  O   . LEU D 2 64  ? -39.131 -13.04  34.283  1   38.14  ? 234 LEU D O   1 
ATOM   7389 C  CB  . LEU D 2 64  ? -41.455 -10.853 35.458  1   39.57  ? 234 LEU D CB  1 
ATOM   7390 C  CG  . LEU D 2 64  ? -42.48  -9.87   34.862  1   41.28  ? 234 LEU D CG  1 
ATOM   7391 C  CD1 . LEU D 2 64  ? -42.44  -8.551  35.619  1   36.92  ? 234 LEU D CD1 1 
ATOM   7392 C  CD2 . LEU D 2 64  ? -42.326 -9.587  33.372  1   38.61  ? 234 LEU D CD2 1 
ATOM   7393 N  N   . ALA D 2 65  ? -39.826 -13.348 36.426  1   37.2   ? 235 ALA D N   1 
ATOM   7394 C  CA  . ALA D 2 65  ? -38.583 -13.964 36.862  1   36.87  ? 235 ALA D CA  1 
ATOM   7395 C  C   . ALA D 2 65  ? -38.235 -15.133 35.937  1   37.4   ? 235 ALA D C   1 
ATOM   7396 O  O   . ALA D 2 65  ? -37.132 -15.197 35.384  1   37.16  ? 235 ALA D O   1 
ATOM   7397 C  CB  . ALA D 2 65  ? -38.652 -14.352 38.32   1   33.01  ? 235 ALA D CB  1 
ATOM   7398 N  N   . VAL D 2 66  ? -39.212 -16.01  35.696  1   36.9   ? 236 VAL D N   1 
ATOM   7399 C  CA  . VAL D 2 66  ? -38.994 -17.157 34.829  1   35.14  ? 236 VAL D CA  1 
ATOM   7400 C  C   . VAL D 2 66  ? -38.616 -16.719 33.403  1   38.08  ? 236 VAL D C   1 
ATOM   7401 O  O   . VAL D 2 66  ? -37.74  -17.323 32.788  1   42.08  ? 236 VAL D O   1 
ATOM   7402 C  CB  . VAL D 2 66  ? -40.171 -18.145 34.887  1   32.31  ? 236 VAL D CB  1 
ATOM   7403 C  CG1 . VAL D 2 66  ? -39.925 -19.34  33.982  1   29.81  ? 236 VAL D CG1 1 
ATOM   7404 C  CG2 . VAL D 2 66  ? -40.44  -18.598 36.328  1   31.77  ? 236 VAL D CG2 1 
ATOM   7405 N  N   . ASN D 2 67  ? -39.227 -15.647 32.881  1   37.64  ? 237 ASN D N   1 
ATOM   7406 C  CA  . ASN D 2 67  ? -38.865 -15.148 31.564  1   37.56  ? 237 ASN D CA  1 
ATOM   7407 C  C   . ASN D 2 67  ? -37.399 -14.696 31.562  1   40.69  ? 237 ASN D C   1 
ATOM   7408 O  O   . ASN D 2 67  ? -36.667 -14.979 30.602  1   40.07  ? 237 ASN D O   1 
ATOM   7409 C  CB  . ASN D 2 67  ? -39.833 -14.078 31.054  1   35.8   ? 237 ASN D CB  1 
ATOM   7410 C  CG  . ASN D 2 67  ? -39.356 -13.45  29.757  1   38.05  ? 237 ASN D CG  1 
ATOM   7411 O  OD1 . ASN D 2 67  ? -38.559 -12.492 29.77   1   35.13  ? 237 ASN D OD1 1 
ATOM   7412 N  ND2 . ASN D 2 67  ? -39.815 -13.983 28.626  1   36.07  ? 237 ASN D ND2 1 
ATOM   7413 N  N   . TYR D 2 68  ? -37.002 -13.952 32.616  1   34.89  ? 238 TYR D N   1 
ATOM   7414 C  CA  . TYR D 2 68  ? -35.65  -13.429 32.717  1   33.96  ? 238 TYR D CA  1 
ATOM   7415 C  C   . TYR D 2 68  ? -34.628 -14.564 32.713  1   34.61  ? 238 TYR D C   1 
ATOM   7416 O  O   . TYR D 2 68  ? -33.614 -14.462 32.038  1   38.94  ? 238 TYR D O   1 
ATOM   7417 C  CB  . TYR D 2 68  ? -35.496 -12.542 33.955  1   35.44  ? 238 TYR D CB  1 
ATOM   7418 C  CG  . TYR D 2 68  ? -36.41  -11.325 34.01   1   35.86  ? 238 TYR D CG  1 
ATOM   7419 C  CD1 . TYR D 2 68  ? -37.163 -10.927 32.895  1   36.05  ? 238 TYR D CD1 1 
ATOM   7420 C  CD2 . TYR D 2 68  ? -36.505 -10.569 35.176  1   32.24  ? 238 TYR D CD2 1 
ATOM   7421 C  CE1 . TYR D 2 68  ? -37.981 -9.805  32.946  1   36.46  ? 238 TYR D CE1 1 
ATOM   7422 C  CE2 . TYR D 2 68  ? -37.298 -9.431  35.232  1   33.62  ? 238 TYR D CE2 1 
ATOM   7423 C  CZ  . TYR D 2 68  ? -38.023 -9.052  34.115  1   34.65  ? 238 TYR D CZ  1 
ATOM   7424 O  OH  . TYR D 2 68  ? -38.836 -7.988  34.203  1   33.4   ? 238 TYR D OH  1 
ATOM   7425 N  N   . ILE D 2 69  ? -34.895 -15.64  33.473  1   38.78  ? 239 ILE D N   1 
ATOM   7426 C  CA  . ILE D 2 69  ? -34.054 -16.831 33.597  1   36.69  ? 239 ILE D CA  1 
ATOM   7427 C  C   . ILE D 2 69  ? -33.882 -17.552 32.255  1   37.13  ? 239 ILE D C   1 
ATOM   7428 O  O   . ILE D 2 69  ? -32.76  -17.804 31.825  1   34.27  ? 239 ILE D O   1 
ATOM   7429 C  CB  . ILE D 2 69  ? -34.633 -17.77  34.662  1   32.56  ? 239 ILE D CB  1 
ATOM   7430 C  CG1 . ILE D 2 69  ? -34.612 -17.056 36.028  1   31.11  ? 239 ILE D CG1 1 
ATOM   7431 C  CG2 . ILE D 2 69  ? -33.856 -19.085 34.675  1   28.83  ? 239 ILE D CG2 1 
ATOM   7432 C  CD1 . ILE D 2 69  ? -35.449 -17.747 37.087  1   29.65  ? 239 ILE D CD1 1 
ATOM   7433 N  N   . ASP D 2 70  ? -34.994 -17.861 31.587  1   36.65  ? 240 ASP D N   1 
ATOM   7434 C  CA  . ASP D 2 70  ? -34.934 -18.564 30.314  1   36.19  ? 240 ASP D CA  1 
ATOM   7435 C  C   . ASP D 2 70  ? -34.151 -17.756 29.291  1   37     ? 240 ASP D C   1 
ATOM   7436 O  O   . ASP D 2 70  ? -33.367 -18.32  28.544  1   40.61  ? 240 ASP D O   1 
ATOM   7437 C  CB  . ASP D 2 70  ? -36.289 -19.07  29.846  1   35.11  ? 240 ASP D CB  1 
ATOM   7438 C  CG  . ASP D 2 70  ? -36.92  -20.091 30.781  1   38.32  ? 240 ASP D CG  1 
ATOM   7439 O  OD1 . ASP D 2 70  ? -36.157 -20.909 31.366  1   38.25  ? 240 ASP D OD1 1 
ATOM   7440 O  OD2 . ASP D 2 70  ? -38.167 -20.07  30.919  1   39.69  ? 240 ASP D OD2 1 
ATOM   7441 N  N   . ARG D 2 71  ? -34.255 -16.438 29.312  1   35.42  ? 241 ARG D N   1 
ATOM   7442 C  CA  . ARG D 2 71  ? -33.557 -15.658 28.268  1   34.11  ? 241 ARG D CA  1 
ATOM   7443 C  C   . ARG D 2 71  ? -32.052 -15.597 28.582  1   33.64  ? 241 ARG D C   1 
ATOM   7444 O  O   . ARG D 2 71  ? -31.254 -15.569 27.635  1   33.53  ? 241 ARG D O   1 
ATOM   7445 C  CB  . ARG D 2 71  ? -34.263 -14.306 28.147  1   34.16  ? 241 ARG D CB  1 
ATOM   7446 C  CG  . ARG D 2 71  ? -35.494 -14.33  27.257  1   38.27  ? 241 ARG D CG  1 
ATOM   7447 C  CD  . ARG D 2 71  ? -36.363 -13.124 27.516  1   36.83  ? 241 ARG D CD  1 
ATOM   7448 N  NE  . ARG D 2 71  ? -35.639 -11.86  27.361  1   38.7   ? 241 ARG D NE  1 
ATOM   7449 C  CZ  . ARG D 2 71  ? -36.009 -10.716 27.909  1   38.98  ? 241 ARG D CZ  1 
ATOM   7450 N  NH1 . ARG D 2 71  ? -37.011 -10.685 28.765  1   37.54  ? 241 ARG D NH1 1 
ATOM   7451 N  NH2 . ARG D 2 71  ? -35.374 -9.604  27.6    1   38.64  ? 241 ARG D NH2 1 
ATOM   7452 N  N   . PHE D 2 72  ? -31.688 -15.6   29.86   1   32.78  ? 242 PHE D N   1 
ATOM   7453 C  CA  . PHE D 2 72  ? -30.262 -15.538 30.271  1   33.18  ? 242 PHE D CA  1 
ATOM   7454 C  C   . PHE D 2 72  ? -29.589 -16.865 29.961  1   33.76  ? 242 PHE D C   1 
ATOM   7455 O  O   . PHE D 2 72  ? -28.487 -16.865 29.412  1   32.16  ? 242 PHE D O   1 
ATOM   7456 C  CB  . PHE D 2 72  ? -30.202 -15.184 31.76   1   30.78  ? 242 PHE D CB  1 
ATOM   7457 C  CG  . PHE D 2 72  ? -28.813 -14.975 32.343  1   31.33  ? 242 PHE D CG  1 
ATOM   7458 C  CD1 . PHE D 2 72  ? -28.205 -13.729 32.302  1   31     ? 242 PHE D CD1 1 
ATOM   7459 C  CD2 . PHE D 2 72  ? -28.127 -16.023 32.941  1   32.72  ? 242 PHE D CD2 1 
ATOM   7460 C  CE1 . PHE D 2 72  ? -26.945 -13.542 32.839  1   33.23  ? 242 PHE D CE1 1 
ATOM   7461 C  CE2 . PHE D 2 72  ? -26.867 -15.828 33.475  1   34.41  ? 242 PHE D CE2 1 
ATOM   7462 C  CZ  . PHE D 2 72  ? -26.28  -14.591 33.422  1   33.67  ? 242 PHE D CZ  1 
ATOM   7463 N  N   . LEU D 2 73  ? -30.252 -17.963 30.299  1   32.12  ? 243 LEU D N   1 
ATOM   7464 C  CA  . LEU D 2 73  ? -29.707 -19.316 30.061  1   34.5   ? 243 LEU D CA  1 
ATOM   7465 C  C   . LEU D 2 73  ? -29.761 -19.645 28.564  1   38.49  ? 243 LEU D C   1 
ATOM   7466 O  O   . LEU D 2 73  ? -29.111 -20.615 28.155  1   39.5   ? 243 LEU D O   1 
ATOM   7467 C  CB  . LEU D 2 73  ? -30.545 -20.27  30.901  1   35.92  ? 243 LEU D CB  1 
ATOM   7468 C  CG  . LEU D 2 73  ? -30.37  -20.183 32.418  1   34.98  ? 243 LEU D CG  1 
ATOM   7469 C  CD1 . LEU D 2 73  ? -31.232 -21.248 33.054  1   30.97  ? 243 LEU D CD1 1 
ATOM   7470 C  CD2 . LEU D 2 73  ? -28.921 -20.396 32.775  1   34.27  ? 243 LEU D CD2 1 
ATOM   7471 N  N   . SER D 2 74  ? -30.488 -18.848 27.786  1   38.06  ? 244 SER D N   1 
ATOM   7472 C  CA  . SER D 2 74  ? -30.536 -19.022 26.318  1   40.92  ? 244 SER D CA  1 
ATOM   7473 C  C   . SER D 2 74  ? -29.287 -18.384 25.703  1   44.48  ? 244 SER D C   1 
ATOM   7474 O  O   . SER D 2 74  ? -29.018 -18.647 24.53   1   46.01  ? 244 SER D O   1 
ATOM   7475 C  CB  . SER D 2 74  ? -31.796 -18.429 25.76   1   41.39  ? 244 SER D CB  1 
ATOM   7476 O  OG  . SER D 2 74  ? -32.924 -19.247 26.026  1   42.63  ? 244 SER D OG  1 
ATOM   7477 N  N   . SER D 2 75  ? -28.534 -17.619 26.493  1   42.85  ? 245 SER D N   1 
ATOM   7478 C  CA  . SER D 2 75  ? -27.333 -16.912 25.986  1   45.15  ? 245 SER D CA  1 
ATOM   7479 C  C   . SER D 2 75  ? -26.099 -17.193 26.847  1   41.64  ? 245 SER D C   1 
ATOM   7480 O  O   . SER D 2 75  ? -24.986 -16.959 26.359  1   46.13  ? 245 SER D O   1 
ATOM   7481 C  CB  . SER D 2 75  ? -27.584 -15.434 25.933  1   49.41  ? 245 SER D CB  1 
ATOM   7482 O  OG  . SER D 2 75  ? -28.596 -15.105 24.993  1   56.01  ? 245 SER D OG  1 
ATOM   7483 N  N   . MET D 2 76  ? -26.279 -17.654 28.077  1   35.67  ? 246 MET D N   1 
ATOM   7484 C  CA  . MET D 2 76  ? -25.108 -17.789 28.975  1   35.97  ? 246 MET D CA  1 
ATOM   7485 C  C   . MET D 2 76  ? -25.026 -19.176 29.613  1   36.66  ? 246 MET D C   1 
ATOM   7486 O  O   . MET D 2 76  ? -26.009 -19.616 30.225  1   37.66  ? 246 MET D O   1 
ATOM   7487 C  CB  . MET D 2 76  ? -25.157 -16.746 30.092  1   35.8   ? 246 MET D CB  1 
ATOM   7488 C  CG  . MET D 2 76  ? -25.327 -15.328 29.613  1   38.95  ? 246 MET D CG  1 
ATOM   7489 S  SD  . MET D 2 76  ? -23.741 -14.654 29.092  1   45.38  ? 246 MET D SD  1 
ATOM   7490 C  CE  . MET D 2 76  ? -22.997 -14.382 30.704  1   40.83  ? 246 MET D CE  1 
ATOM   7491 N  N   . SER D 2 77  ? -23.869 -19.813 29.483  1   36.44  ? 247 SER D N   1 
ATOM   7492 C  CA  . SER D 2 77  ? -23.643 -21.121 30.13   1   36.77  ? 247 SER D CA  1 
ATOM   7493 C  C   . SER D 2 77  ? -23.549 -20.907 31.641  1   36.83  ? 247 SER D C   1 
ATOM   7494 O  O   . SER D 2 77  ? -22.837 -19.984 32.056  1   38.46  ? 247 SER D O   1 
ATOM   7495 C  CB  . SER D 2 77  ? -22.406 -21.758 29.592  1   36.68  ? 247 SER D CB  1 
ATOM   7496 O  OG  . SER D 2 77  ? -22.589 -22.17  28.248  1   39.02  ? 247 SER D OG  1 
ATOM   7497 N  N   . VAL D 2 78  ? -24.259 -21.719 32.42   1   34.77  ? 248 VAL D N   1 
ATOM   7498 C  CA  . VAL D 2 78  ? -24.24  -21.516 33.856  1   35.83  ? 248 VAL D CA  1 
ATOM   7499 C  C   . VAL D 2 78  ? -23.947 -22.866 34.477  1   38.3   ? 248 VAL D C   1 
ATOM   7500 O  O   . VAL D 2 78  ? -24.531 -23.852 34.043  1   41.75  ? 248 VAL D O   1 
ATOM   7501 C  CB  . VAL D 2 78  ? -25.555 -20.904 34.379  1   34.86  ? 248 VAL D CB  1 
ATOM   7502 C  CG1 . VAL D 2 78  ? -25.701 -21.028 35.899  1   33.46  ? 248 VAL D CG1 1 
ATOM   7503 C  CG2 . VAL D 2 78  ? -25.714 -19.467 33.894  1   32.38  ? 248 VAL D CG2 1 
ATOM   7504 N  N   . LEU D 2 79  ? -23.011 -22.903 35.433  1   39.34  ? 249 LEU D N   1 
ATOM   7505 C  CA  . LEU D 2 79  ? -22.735 -24.124 36.167  1   39.71  ? 249 LEU D CA  1 
ATOM   7506 C  C   . LEU D 2 79  ? -23.847 -24.309 37.192  1   40.8   ? 249 LEU D C   1 
ATOM   7507 O  O   . LEU D 2 79  ? -24.5   -23.346 37.614  1   39.46  ? 249 LEU D O   1 
ATOM   7508 C  CB  . LEU D 2 79  ? -21.365 -24.081 36.844  1   41.27  ? 249 LEU D CB  1 
ATOM   7509 C  CG  . LEU D 2 79  ? -20.146 -24.079 35.91   1   44.51  ? 249 LEU D CG  1 
ATOM   7510 C  CD1 . LEU D 2 79  ? -18.9   -24.294 36.743  1   47.49  ? 249 LEU D CD1 1 
ATOM   7511 C  CD2 . LEU D 2 79  ? -20.206 -25.08  34.765  1   42.65  ? 249 LEU D CD2 1 
ATOM   7512 N  N   . ARG D 2 80  ? -24.021 -25.564 37.602  1   40.2   ? 250 ARG D N   1 
ATOM   7513 C  CA  . ARG D 2 80  ? -25.021 -25.953 38.581  1   42.57  ? 250 ARG D CA  1 
ATOM   7514 C  C   . ARG D 2 80  ? -24.999 -25.094 39.851  1   40.61  ? 250 ARG D C   1 
ATOM   7515 O  O   . ARG D 2 80  ? -26.058 -24.732 40.343  1   40.72  ? 250 ARG D O   1 
ATOM   7516 C  CB  . ARG D 2 80  ? -24.782 -27.412 38.951  1   47.16  ? 250 ARG D CB  1 
ATOM   7517 C  CG  . ARG D 2 80  ? -26.028 -27.888 39.663  1   54.26  ? 250 ARG D CG  1 
ATOM   7518 C  CD  . ARG D 2 80  ? -25.971 -29.383 39.726  1   62.03  ? 250 ARG D CD  1 
ATOM   7519 N  NE  . ARG D 2 80  ? -24.714 -29.845 40.314  1   61.64  ? 250 ARG D NE  1 
ATOM   7520 C  CZ  . ARG D 2 80  ? -24.476 -31.139 40.402  1   65.64  ? 250 ARG D CZ  1 
ATOM   7521 N  NH1 . ARG D 2 80  ? -25.328 -32.006 39.86   1   62.45  ? 250 ARG D NH1 1 
ATOM   7522 N  NH2 . ARG D 2 80  ? -23.383 -31.54  41.018  1   65.63  ? 250 ARG D NH2 1 
ATOM   7523 N  N   . GLY D 2 81  ? -23.816 -24.778 40.391  1   38.19  ? 251 GLY D N   1 
ATOM   7524 C  CA  . GLY D 2 81  ? -23.738 -24.105 41.676  1   35.74  ? 251 GLY D CA  1 
ATOM   7525 C  C   . GLY D 2 81  ? -24.093 -22.633 41.533  1   36.58  ? 251 GLY D C   1 
ATOM   7526 O  O   . GLY D 2 81  ? -24.121 -21.891 42.511  1   36.63  ? 251 GLY D O   1 
ATOM   7527 N  N   . LYS D 2 82  ? -24.356 -22.21  40.293  1   36.18  ? 252 LYS D N   1 
ATOM   7528 C  CA  . LYS D 2 82  ? -24.624 -20.809 40.033  1   34.36  ? 252 LYS D CA  1 
ATOM   7529 C  C   . LYS D 2 82  ? -26.076 -20.629 39.6    1   35.01  ? 252 LYS D C   1 
ATOM   7530 O  O   . LYS D 2 82  ? -26.525 -19.496 39.446  1   36.36  ? 252 LYS D O   1 
ATOM   7531 C  CB  . LYS D 2 82  ? -23.547 -20.24  39.099  1   34.43  ? 252 LYS D CB  1 
ATOM   7532 C  CG  . LYS D 2 82  ? -22.157 -20.084 39.748  1   33.76  ? 252 LYS D CG  1 
ATOM   7533 C  CD  . LYS D 2 82  ? -22.289 -19.348 41.078  1   33.44  ? 252 LYS D CD  1 
ATOM   7534 C  CE  . LYS D 2 82  ? -21.07  -18.666 41.62   1   34.88  ? 252 LYS D CE  1 
ATOM   7535 N  NZ  . LYS D 2 82  ? -19.99  -19.646 41.694  1   37.63  ? 252 LYS D NZ  1 
ATOM   7536 N  N   . LEU D 2 83  ? -26.824 -21.736 39.444  1   36.1   ? 253 LEU D N   1 
ATOM   7537 C  CA  . LEU D 2 83  ? -28.176 -21.687 38.896  1   35.05  ? 253 LEU D CA  1 
ATOM   7538 C  C   . LEU D 2 83  ? -29.09  -20.863 39.808  1   36.03  ? 253 LEU D C   1 
ATOM   7539 O  O   . LEU D 2 83  ? -29.834 -19.991 39.362  1   36.25  ? 253 LEU D O   1 
ATOM   7540 C  CB  . LEU D 2 83  ? -28.741 -23.093 38.733  1   32.54  ? 253 LEU D CB  1 
ATOM   7541 C  CG  . LEU D 2 83  ? -30.114 -23.137 38.059  1   31.56  ? 253 LEU D CG  1 
ATOM   7542 C  CD1 . LEU D 2 83  ? -30.135 -22.435 36.688  1   28.47  ? 253 LEU D CD1 1 
ATOM   7543 C  CD2 . LEU D 2 83  ? -30.467 -24.605 37.912  1   32.29  ? 253 LEU D CD2 1 
ATOM   7544 N  N   . GLN D 2 84  ? -29.041 -21.166 41.104  1   36.77  ? 254 GLN D N   1 
ATOM   7545 C  CA  . GLN D 2 84  ? -29.861 -20.451 42.061  1   38.26  ? 254 GLN D CA  1 
ATOM   7546 C  C   . GLN D 2 84  ? -29.486 -18.966 42.089  1   37.75  ? 254 GLN D C   1 
ATOM   7547 O  O   . GLN D 2 84  ? -30.304 -18.118 42.459  1   38.01  ? 254 GLN D O   1 
ATOM   7548 C  CB  . GLN D 2 84  ? -29.708 -21.072 43.446  1   38.44  ? 254 GLN D CB  1 
ATOM   7549 C  CG  . GLN D 2 84  ? -30.652 -20.448 44.461  1   39.83  ? 254 GLN D CG  1 
ATOM   7550 C  CD  . GLN D 2 84  ? -30.631 -21.125 45.803  1   40.97  ? 254 GLN D CD  1 
ATOM   7551 O  OE1 . GLN D 2 84  ? -31.528 -20.913 46.614  1   45.52  ? 254 GLN D OE1 1 
ATOM   7552 N  NE2 . GLN D 2 84  ? -29.625 -21.949 46.049  1   44.17  ? 254 GLN D NE2 1 
ATOM   7553 N  N   . LEU D 2 85  ? -28.238 -18.652 41.735  1   33.36  ? 255 LEU D N   1 
ATOM   7554 C  CA  . LEU D 2 85  ? -27.828 -17.267 41.84   1   34.27  ? 255 LEU D CA  1 
ATOM   7555 C  C   . LEU D 2 85  ? -28.445 -16.491 40.673  1   33.64  ? 255 LEU D C   1 
ATOM   7556 O  O   . LEU D 2 85  ? -28.861 -15.353 40.823  1   33.13  ? 255 LEU D O   1 
ATOM   7557 C  CB  . LEU D 2 85  ? -26.306 -17.145 41.921  1   32.99  ? 255 LEU D CB  1 
ATOM   7558 C  CG  . LEU D 2 85  ? -25.772 -15.721 41.805  1   31.96  ? 255 LEU D CG  1 
ATOM   7559 C  CD1 . LEU D 2 85  ? -26.206 -14.836 42.973  1   31.51  ? 255 LEU D CD1 1 
ATOM   7560 C  CD2 . LEU D 2 85  ? -24.268 -15.81  41.715  1   32.61  ? 255 LEU D CD2 1 
ATOM   7561 N  N   . VAL D 2 86  ? -28.572 -17.144 39.521  1   32.88  ? 256 VAL D N   1 
ATOM   7562 C  CA  . VAL D 2 86  ? -29.246 -16.516 38.401  1   31.16  ? 256 VAL D CA  1 
ATOM   7563 C  C   . VAL D 2 86  ? -30.703 -16.252 38.786  1   33.05  ? 256 VAL D C   1 
ATOM   7564 O  O   . VAL D 2 86  ? -31.202 -15.148 38.574  1   36.48  ? 256 VAL D O   1 
ATOM   7565 C  CB  . VAL D 2 86  ? -29.135 -17.395 37.142  1   30.24  ? 256 VAL D CB  1 
ATOM   7566 C  CG1 . VAL D 2 86  ? -29.956 -16.811 35.994  1   27.37  ? 256 VAL D CG1 1 
ATOM   7567 C  CG2 . VAL D 2 86  ? -27.676 -17.567 36.738  1   29.6   ? 256 VAL D CG2 1 
ATOM   7568 N  N   . GLY D 2 87  ? -31.361 -17.273 39.356  1   31.6   ? 257 GLY D N   1 
ATOM   7569 C  CA  . GLY D 2 87  ? -32.755 -17.249 39.765  1   30.25  ? 257 GLY D CA  1 
ATOM   7570 C  C   . GLY D 2 87  ? -33.053 -16.145 40.781  1   33.54  ? 257 GLY D C   1 
ATOM   7571 O  O   . GLY D 2 87  ? -34.011 -15.41  40.603  1   36.57  ? 257 GLY D O   1 
ATOM   7572 N  N   . THR D 2 88  ? -32.235 -16.023 41.842  1   33.34  ? 258 THR D N   1 
ATOM   7573 C  CA  . THR D 2 88  ? -32.391 -15.008 42.876  1   34.28  ? 258 THR D CA  1 
ATOM   7574 C  C   . THR D 2 88  ? -32.306 -13.639 42.2    1   36.49  ? 258 THR D C   1 
ATOM   7575 O  O   . THR D 2 88  ? -33.091 -12.729 42.49   1   35.83  ? 258 THR D O   1 
ATOM   7576 C  CB  . THR D 2 88  ? -31.279 -15.175 43.924  1   34.75  ? 258 THR D CB  1 
ATOM   7577 O  OG1 . THR D 2 88  ? -31.314 -16.513 44.412  1   40.39  ? 258 THR D OG1 1 
ATOM   7578 C  CG2 . THR D 2 88  ? -31.466 -14.33  45.163  1   32.34  ? 258 THR D CG2 1 
ATOM   7579 N  N   . ALA D 2 89  ? -31.301 -13.485 41.32   1   37.78  ? 259 ALA D N   1 
ATOM   7580 C  CA  . ALA D 2 89  ? -31.095 -12.196 40.678  1   36.22  ? 259 ALA D CA  1 
ATOM   7581 C  C   . ALA D 2 89  ? -32.289 -11.85  39.795  1   33.04  ? 259 ALA D C   1 
ATOM   7582 O  O   . ALA D 2 89  ? -32.712 -10.708 39.788  1   33.24  ? 259 ALA D O   1 
ATOM   7583 C  CB  . ALA D 2 89  ? -29.796 -12.145 39.927  1   35.49  ? 259 ALA D CB  1 
ATOM   7584 N  N   . ALA D 2 90  ? -32.869 -12.847 39.118  1   31.3   ? 260 ALA D N   1 
ATOM   7585 C  CA  . ALA D 2 90  ? -34.063 -12.612 38.305  1   32.25  ? 260 ALA D CA  1 
ATOM   7586 C  C   . ALA D 2 90  ? -35.258 -12.203 39.17   1   34.96  ? 260 ALA D C   1 
ATOM   7587 O  O   . ALA D 2 90  ? -36.017 -11.309 38.797  1   40.37  ? 260 ALA D O   1 
ATOM   7588 C  CB  . ALA D 2 90  ? -34.397 -13.825 37.481  1   29.34  ? 260 ALA D CB  1 
ATOM   7589 N  N   . MET D 2 91  ? -35.415 -12.846 40.338  1   33.68  ? 261 MET D N   1 
ATOM   7590 C  CA  . MET D 2 91  ? -36.543 -12.56  41.205  1   33.66  ? 261 MET D CA  1 
ATOM   7591 C  C   . MET D 2 91  ? -36.392 -11.125 41.706  1   33.63  ? 261 MET D C   1 
ATOM   7592 O  O   . MET D 2 91  ? -37.356 -10.384 41.783  1   35.7   ? 261 MET D O   1 
ATOM   7593 C  CB  . MET D 2 91  ? -36.607 -13.59  42.347  1   35.88  ? 261 MET D CB  1 
ATOM   7594 C  CG  . MET D 2 91  ? -37.991 -13.772 42.977  1   38.89  ? 261 MET D CG  1 
ATOM   7595 S  SD  . MET D 2 91  ? -39.269 -14.192 41.767  1   40.86  ? 261 MET D SD  1 
ATOM   7596 C  CE  . MET D 2 91  ? -40.51  -14.801 42.917  1   36.82  ? 261 MET D CE  1 
ATOM   7597 N  N   . LEU D 2 92  ? -35.151 -10.725 41.997  1   32.72  ? 262 LEU D N   1 
ATOM   7598 C  CA  . LEU D 2 92  ? -34.888 -9.397  42.499  1   33.58  ? 262 LEU D CA  1 
ATOM   7599 C  C   . LEU D 2 92  ? -35.268 -8.389  41.419  1   34.58  ? 262 LEU D C   1 
ATOM   7600 O  O   . LEU D 2 92  ? -35.997 -7.428  41.674  1   36.64  ? 262 LEU D O   1 
ATOM   7601 C  CB  . LEU D 2 92  ? -33.404 -9.325  42.862  1   34.42  ? 262 LEU D CB  1 
ATOM   7602 C  CG  . LEU D 2 92  ? -32.883 -7.927  43.227  1   33     ? 262 LEU D CG  1 
ATOM   7603 C  CD1 . LEU D 2 92  ? -33.702 -7.375  44.383  1   33.31  ? 262 LEU D CD1 1 
ATOM   7604 C  CD2 . LEU D 2 92  ? -31.389 -7.909  43.509  1   31.18  ? 262 LEU D CD2 1 
ATOM   7605 N  N   . LEU D 2 93  ? -34.77  -8.615  40.2    1   34.17  ? 263 LEU D N   1 
ATOM   7606 C  CA  . LEU D 2 93  ? -35.079 -7.734  39.088  1   33.54  ? 263 LEU D CA  1 
ATOM   7607 C  C   . LEU D 2 93  ? -36.578 -7.653  38.825  1   34.5   ? 263 LEU D C   1 
ATOM   7608 O  O   . LEU D 2 93  ? -37.11  -6.553  38.628  1   34.94  ? 263 LEU D O   1 
ATOM   7609 C  CB  . LEU D 2 93  ? -34.322 -8.185  37.857  1   33.02  ? 263 LEU D CB  1 
ATOM   7610 C  CG  . LEU D 2 93  ? -32.851 -7.788  37.886  1   34.53  ? 263 LEU D CG  1 
ATOM   7611 C  CD1 . LEU D 2 93  ? -32.107 -8.486  36.758  1   33.54  ? 263 LEU D CD1 1 
ATOM   7612 C  CD2 . LEU D 2 93  ? -32.716 -6.269  37.819  1   35.07  ? 263 LEU D CD2 1 
ATOM   7613 N  N   . ALA D 2 94  ? -37.245 -8.81   38.809  1   31.72  ? 264 ALA D N   1 
ATOM   7614 C  CA  . ALA D 2 94  ? -38.679 -8.816  38.575  1   33.27  ? 264 ALA D CA  1 
ATOM   7615 C  C   . ALA D 2 94  ? -39.409 -8.046  39.678  1   35.37  ? 264 ALA D C   1 
ATOM   7616 O  O   . ALA D 2 94  ? -40.379 -7.347  39.394  1   37.89  ? 264 ALA D O   1 
ATOM   7617 C  CB  . ALA D 2 94  ? -39.175 -10.234 38.452  1   35.42  ? 264 ALA D CB  1 
ATOM   7618 N  N   . SER D 2 95  ? -38.928 -8.147  40.928  1   32.99  ? 265 SER D N   1 
ATOM   7619 C  CA  . SER D 2 95  ? -39.532 -7.451  42.053  1   33.87  ? 265 SER D CA  1 
ATOM   7620 C  C   . SER D 2 95  ? -39.376 -5.94   41.886  1   35.14  ? 265 SER D C   1 
ATOM   7621 O  O   . SER D 2 95  ? -40.319 -5.169  42.107  1   38.29  ? 265 SER D O   1 
ATOM   7622 C  CB  . SER D 2 95  ? -38.931 -7.904  43.372  1   34.48  ? 265 SER D CB  1 
ATOM   7623 O  OG  . SER D 2 95  ? -39.211 -9.28   43.585  1   35.38  ? 265 SER D OG  1 
ATOM   7624 N  N   . LYS D 2 96  ? -38.155 -5.514  41.529  1   32.75  ? 266 LYS D N   1 
ATOM   7625 C  CA  . LYS D 2 96  ? -37.872 -4.101  41.339  1   32.06  ? 266 LYS D CA  1 
ATOM   7626 C  C   . LYS D 2 96  ? -38.794 -3.54   40.271  1   32.02  ? 266 LYS D C   1 
ATOM   7627 O  O   . LYS D 2 96  ? -39.388 -2.5    40.476  1   34.63  ? 266 LYS D O   1 
ATOM   7628 C  CB  . LYS D 2 96  ? -36.393 -3.913  41.007  1   31.71  ? 266 LYS D CB  1 
ATOM   7629 C  CG  . LYS D 2 96  ? -35.535 -3.962  42.262  1   31.91  ? 266 LYS D CG  1 
ATOM   7630 C  CD  . LYS D 2 96  ? -34.063 -3.752  41.938  1   32.82  ? 266 LYS D CD  1 
ATOM   7631 C  CE  . LYS D 2 96  ? -33.218 -3.506  43.14   1   33.04  ? 266 LYS D CE  1 
ATOM   7632 N  NZ  . LYS D 2 96  ? -31.852 -3.236  42.684  1   31.84  ? 266 LYS D NZ  1 
ATOM   7633 N  N   . PHE D 2 97  ? -38.952 -4.276  39.163  1   33.18  ? 267 PHE D N   1 
ATOM   7634 C  CA  . PHE D 2 97  ? -39.782 -3.87   38.046  1   33.44  ? 267 PHE D CA  1 
ATOM   7635 C  C   . PHE D 2 97  ? -41.258 -3.776  38.447  1   36.33  ? 267 PHE D C   1 
ATOM   7636 O  O   . PHE D 2 97  ? -41.913 -2.777  38.156  1   35.4   ? 267 PHE D O   1 
ATOM   7637 C  CB  . PHE D 2 97  ? -39.568 -4.855  36.897  1   30.31  ? 267 PHE D CB  1 
ATOM   7638 C  CG  . PHE D 2 97  ? -40.322 -4.428  35.642  1   32.18  ? 267 PHE D CG  1 
ATOM   7639 C  CD1 . PHE D 2 97  ? -39.744 -3.554  34.713  1   33.01  ? 267 PHE D CD1 1 
ATOM   7640 C  CD2 . PHE D 2 97  ? -41.622 -4.874  35.388  1   33.8   ? 267 PHE D CD2 1 
ATOM   7641 C  CE1 . PHE D 2 97  ? -40.431 -3.166  33.555  1   33.85  ? 267 PHE D CE1 1 
ATOM   7642 C  CE2 . PHE D 2 97  ? -42.304 -4.496  34.219  1   34.48  ? 267 PHE D CE2 1 
ATOM   7643 C  CZ  . PHE D 2 97  ? -41.718 -3.632  33.312  1   33.5   ? 267 PHE D CZ  1 
ATOM   7644 N  N   . GLU D 2 98  ? -41.784 -4.827  39.106  1   36.84  ? 268 GLU D N   1 
ATOM   7645 C  CA  . GLU D 2 98  ? -43.221 -5.046  39.154  1   35.18  ? 268 GLU D CA  1 
ATOM   7646 C  C   . GLU D 2 98  ? -43.81  -4.698  40.516  1   36.8   ? 268 GLU D C   1 
ATOM   7647 O  O   . GLU D 2 98  ? -44.996 -4.406  40.599  1   39.33  ? 268 GLU D O   1 
ATOM   7648 C  CB  . GLU D 2 98  ? -43.493 -6.528  38.909  1   33.76  ? 268 GLU D CB  1 
ATOM   7649 C  CG  . GLU D 2 98  ? -44.948 -6.834  38.575  1   35.25  ? 268 GLU D CG  1 
ATOM   7650 C  CD  . GLU D 2 98  ? -45.507 -6.042  37.4    1   38.16  ? 268 GLU D CD  1 
ATOM   7651 O  OE1 . GLU D 2 98  ? -44.836 -5.843  36.349  1   37.3   ? 268 GLU D OE1 1 
ATOM   7652 O  OE2 . GLU D 2 98  ? -46.665 -5.62   37.562  1   39.29  ? 268 GLU D OE2 1 
ATOM   7653 N  N   . GLU D 2 99  ? -43.027 -4.772  41.598  1   36.39  ? 269 GLU D N   1 
ATOM   7654 C  CA  . GLU D 2 99  ? -43.661 -4.67   42.902  1   38.01  ? 269 GLU D CA  1 
ATOM   7655 C  C   . GLU D 2 99  ? -43.653 -3.236  43.401  1   41.83  ? 269 GLU D C   1 
ATOM   7656 O  O   . GLU D 2 99  ? -42.645 -2.56   43.253  1   44.35  ? 269 GLU D O   1 
ATOM   7657 C  CB  . GLU D 2 99  ? -42.902 -5.534  43.897  1   38.59  ? 269 GLU D CB  1 
ATOM   7658 C  CG  . GLU D 2 99  ? -42.995 -7.01   43.533  1   39.16  ? 269 GLU D CG  1 
ATOM   7659 C  CD  . GLU D 2 99  ? -44.302 -7.59   44.035  1   44.88  ? 269 GLU D CD  1 
ATOM   7660 O  OE1 . GLU D 2 99  ? -44.926 -7.022  44.985  1   48.45  ? 269 GLU D OE1 1 
ATOM   7661 O  OE2 . GLU D 2 99  ? -44.694 -8.62   43.447  1   43.41  ? 269 GLU D OE2 1 
ATOM   7662 N  N   . ILE D 2 100 ? -44.751 -2.815  44.055  1   44.14  ? 270 ILE D N   1 
ATOM   7663 C  CA  . ILE D 2 100 ? -44.817 -1.527  44.742  1   46.71  ? 270 ILE D CA  1 
ATOM   7664 C  C   . ILE D 2 100 ? -43.785 -1.493  45.87   1   47.94  ? 270 ILE D C   1 
ATOM   7665 O  O   . ILE D 2 100 ? -43.036 -0.533  46.018  1   51.86  ? 270 ILE D O   1 
ATOM   7666 C  CB  . ILE D 2 100 ? -46.225 -1.27   45.309  1   47.02  ? 270 ILE D CB  1 
ATOM   7667 C  CG1 . ILE D 2 100 ? -47.324 -1.314  44.234  1   46.33  ? 270 ILE D CG1 1 
ATOM   7668 C  CG2 . ILE D 2 100 ? -46.257 0.03    46.116  1   44.77  ? 270 ILE D CG2 1 
ATOM   7669 C  CD1 . ILE D 2 100 ? -48.718 -1.112  44.805  1   47.01  ? 270 ILE D CD1 1 
ATOM   7670 N  N   . TYR D 2 101 ? -43.764 -2.566  46.662  1   47.72  ? 271 TYR D N   1 
ATOM   7671 C  CA  . TYR D 2 101 ? -42.915 -2.672  47.832  1   48.06  ? 271 TYR D CA  1 
ATOM   7672 C  C   . TYR D 2 101 ? -42.047 -3.918  47.697  1   48.15  ? 271 TYR D C   1 
ATOM   7673 O  O   . TYR D 2 101 ? -42.222 -4.867  48.469  1   54.01  ? 271 TYR D O   1 
ATOM   7674 C  CB  . TYR D 2 101 ? -43.834 -2.848  49.043  1   47.77  ? 271 TYR D CB  1 
ATOM   7675 C  CG  . TYR D 2 101 ? -44.78  -1.686  49.325  1   48.65  ? 271 TYR D CG  1 
ATOM   7676 C  CD1 . TYR D 2 101 ? -44.284 -0.468  49.759  1   49.49  ? 271 TYR D CD1 1 
ATOM   7677 C  CD2 . TYR D 2 101 ? -46.165 -1.821  49.197  1   50.85  ? 271 TYR D CD2 1 
ATOM   7678 C  CE1 . TYR D 2 101 ? -45.128 0.591   50.06   1   53.45  ? 271 TYR D CE1 1 
ATOM   7679 C  CE2 . TYR D 2 101 ? -47.021 -0.766  49.49   1   53.89  ? 271 TYR D CE2 1 
ATOM   7680 C  CZ  . TYR D 2 101 ? -46.498 0.442   49.922  1   55.82  ? 271 TYR D CZ  1 
ATOM   7681 O  OH  . TYR D 2 101 ? -47.311 1.498   50.229  1   64.57  ? 271 TYR D OH  1 
ATOM   7682 N  N   . PRO D 2 102 ? -41.072 -3.943  46.75   1   42.73  ? 272 PRO D N   1 
ATOM   7683 C  CA  . PRO D 2 102 ? -40.22  -5.111  46.568  1   38.29  ? 272 PRO D CA  1 
ATOM   7684 C  C   . PRO D 2 102 ? -39.45  -5.376  47.859  1   40.71  ? 272 PRO D C   1 
ATOM   7685 O  O   . PRO D 2 102 ? -39.042 -4.452  48.575  1   41.15  ? 272 PRO D O   1 
ATOM   7686 C  CB  . PRO D 2 102 ? -39.28  -4.668  45.444  1   37.27  ? 272 PRO D CB  1 
ATOM   7687 C  CG  . PRO D 2 102 ? -39.221 -3.172  45.559  1   37.4   ? 272 PRO D CG  1 
ATOM   7688 C  CD  . PRO D 2 102 ? -40.64  -2.798  45.929  1   39.97  ? 272 PRO D CD  1 
ATOM   7689 N  N   . PRO D 2 103 ? -39.194 -6.661  48.179  1   41.32  ? 273 PRO D N   1 
ATOM   7690 C  CA  . PRO D 2 103 ? -38.405 -7.003  49.36   1   42.16  ? 273 PRO D CA  1 
ATOM   7691 C  C   . PRO D 2 103 ? -37.006 -6.454  49.114  1   43.37  ? 273 PRO D C   1 
ATOM   7692 O  O   . PRO D 2 103 ? -36.553 -6.42   47.965  1   40.87  ? 273 PRO D O   1 
ATOM   7693 C  CB  . PRO D 2 103 ? -38.397 -8.546  49.411  1   40.39  ? 273 PRO D CB  1 
ATOM   7694 C  CG  . PRO D 2 103 ? -38.943 -8.998  48.08   1   39.04  ? 273 PRO D CG  1 
ATOM   7695 C  CD  . PRO D 2 103 ? -39.62  -7.83   47.389  1   39.24  ? 273 PRO D CD  1 
ATOM   7696 N  N   . GLU D 2 104 ? -36.31  -6.121  50.203  1   47.1   ? 274 GLU D N   1 
ATOM   7697 C  CA  . GLU D 2 104 ? -34.948 -5.607  50.138  1   54.1   ? 274 GLU D CA  1 
ATOM   7698 C  C   . GLU D 2 104 ? -33.967 -6.65   49.609  1   51.72  ? 274 GLU D C   1 
ATOM   7699 O  O   . GLU D 2 104 ? -34.266 -7.843  49.514  1   54.33  ? 274 GLU D O   1 
ATOM   7700 C  CB  . GLU D 2 104 ? -34.494 -5.13   51.516  1   62.41  ? 274 GLU D CB  1 
ATOM   7701 C  CG  . GLU D 2 104 ? -35.365 -4.011  52.081  1   71.41  ? 274 GLU D CG  1 
ATOM   7702 C  CD  . GLU D 2 104 ? -35.064 -3.858  53.556  1   88.6   ? 274 GLU D CD  1 
ATOM   7703 O  OE1 . GLU D 2 104 ? -35.837 -3.155  54.247  1   105.08 ? 274 GLU D OE1 1 
ATOM   7704 O  OE2 . GLU D 2 104 ? -34.047 -4.44   54.014  1   89.85  ? 274 GLU D OE2 1 
ATOM   7705 N  N   . VAL D 2 105 ? -32.776 -6.171  49.245  1   49     ? 275 VAL D N   1 
ATOM   7706 C  CA  . VAL D 2 105 ? -31.774 -7.061  48.684  1   44.43  ? 275 VAL D CA  1 
ATOM   7707 C  C   . VAL D 2 105 ? -31.371 -8.104  49.719  1   41.69  ? 275 VAL D C   1 
ATOM   7708 O  O   . VAL D 2 105 ? -31.185 -9.257  49.362  1   42.8   ? 275 VAL D O   1 
ATOM   7709 C  CB  . VAL D 2 105 ? -30.561 -6.333  48.079  1   44.21  ? 275 VAL D CB  1 
ATOM   7710 C  CG1 . VAL D 2 105 ? -29.448 -7.302  47.721  1   42.92  ? 275 VAL D CG1 1 
ATOM   7711 C  CG2 . VAL D 2 105 ? -30.968 -5.539  46.846  1   44.45  ? 275 VAL D CG2 1 
ATOM   7712 N  N   . ALA D 2 106 ? -31.289 -7.691  50.989  1   42.88  ? 276 ALA D N   1 
ATOM   7713 C  CA  . ALA D 2 106 ? -30.931 -8.555  52.107  1   42.68  ? 276 ALA D CA  1 
ATOM   7714 C  C   . ALA D 2 106 ? -31.863 -9.755  52.179  1   42.75  ? 276 ALA D C   1 
ATOM   7715 O  O   . ALA D 2 106 ? -31.378 -10.844 52.455  1   43.83  ? 276 ALA D O   1 
ATOM   7716 C  CB  . ALA D 2 106 ? -30.864 -7.828  53.426  1   39.84  ? 276 ALA D CB  1 
ATOM   7717 N  N   . GLU D 2 107 ? -33.151 -9.567  51.856  1   42.44  ? 277 GLU D N   1 
ATOM   7718 C  CA  . GLU D 2 107 ? -34.075 -10.691 51.839  1   44.31  ? 277 GLU D CA  1 
ATOM   7719 C  C   . GLU D 2 107 ? -33.709 -11.663 50.723  1   44.93  ? 277 GLU D C   1 
ATOM   7720 O  O   . GLU D 2 107 ? -33.86  -12.871 50.856  1   47.05  ? 277 GLU D O   1 
ATOM   7721 C  CB  . GLU D 2 107 ? -35.536 -10.272 51.738  1   45.72  ? 277 GLU D CB  1 
ATOM   7722 C  CG  . GLU D 2 107 ? -35.984 -9.438  52.937  1   52.28  ? 277 GLU D CG  1 
ATOM   7723 C  CD  . GLU D 2 107 ? -36.232 -10.174 54.247  1   63.03  ? 277 GLU D CD  1 
ATOM   7724 O  OE1 . GLU D 2 107 ? -37.294 -9.886  54.836  1   82     ? 277 GLU D OE1 1 
ATOM   7725 O  OE2 . GLU D 2 107 ? -35.43  -11.008 54.718  1   64.09  ? 277 GLU D OE2 1 
ATOM   7726 N  N   . PHE D 2 108 ? -33.181 -11.154 49.617  1   44.89  ? 278 PHE D N   1 
ATOM   7727 C  CA  . PHE D 2 108 ? -32.895 -12.084 48.543  1   44.12  ? 278 PHE D CA  1 
ATOM   7728 C  C   . PHE D 2 108 ? -31.679 -12.939 48.893  1   46.48  ? 278 PHE D C   1 
ATOM   7729 O  O   . PHE D 2 108 ? -31.504 -14.034 48.347  1   47.23  ? 278 PHE D O   1 
ATOM   7730 C  CB  . PHE D 2 108 ? -32.795 -11.367 47.199  1   40.41  ? 278 PHE D CB  1 
ATOM   7731 C  CG  . PHE D 2 108 ? -34.173 -11.046 46.66   1   39.13  ? 278 PHE D CG  1 
ATOM   7732 C  CD1 . PHE D 2 108 ? -34.929 -12.039 46.035  1   37.78  ? 278 PHE D CD1 1 
ATOM   7733 C  CD2 . PHE D 2 108 ? -34.711 -9.771  46.796  1   39.18  ? 278 PHE D CD2 1 
ATOM   7734 C  CE1 . PHE D 2 108 ? -36.179 -11.772 45.517  1   35     ? 278 PHE D CE1 1 
ATOM   7735 C  CE2 . PHE D 2 108 ? -35.959 -9.5    46.246  1   40.93  ? 278 PHE D CE2 1 
ATOM   7736 C  CZ  . PHE D 2 108 ? -36.687 -10.499 45.617  1   38.77  ? 278 PHE D CZ  1 
ATOM   7737 N  N   . VAL D 2 109 ? -30.836 -12.414 49.789  1   46.08  ? 279 VAL D N   1 
ATOM   7738 C  CA  . VAL D 2 109 ? -29.682 -13.166 50.246  1   46.51  ? 279 VAL D CA  1 
ATOM   7739 C  C   . VAL D 2 109 ? -30.12  -14.211 51.264  1   49.22  ? 279 VAL D C   1 
ATOM   7740 O  O   . VAL D 2 109 ? -29.601 -15.323 51.265  1   50.77  ? 279 VAL D O   1 
ATOM   7741 C  CB  . VAL D 2 109 ? -28.586 -12.256 50.817  1   43.91  ? 279 VAL D CB  1 
ATOM   7742 C  CG1 . VAL D 2 109 ? -27.452 -13.066 51.437  1   40.85  ? 279 VAL D CG1 1 
ATOM   7743 C  CG2 . VAL D 2 109 ? -28.075 -11.333 49.727  1   42.85  ? 279 VAL D CG2 1 
ATOM   7744 N  N   . TYR D 2 110 ? -31.067 -13.828 52.123  1   51.36  ? 280 TYR D N   1 
ATOM   7745 C  CA  . TYR D 2 110 ? -31.516 -14.67  53.21   1   53.74  ? 280 TYR D CA  1 
ATOM   7746 C  C   . TYR D 2 110 ? -32.123 -15.95  52.639  1   51.31  ? 280 TYR D C   1 
ATOM   7747 O  O   . TYR D 2 110 ? -31.796 -17.044 53.096  1   51.61  ? 280 TYR D O   1 
ATOM   7748 C  CB  . TYR D 2 110 ? -32.485 -13.884 54.092  1   60.57  ? 280 TYR D CB  1 
ATOM   7749 C  CG  . TYR D 2 110 ? -32.878 -14.637 55.353  1   73.89  ? 280 TYR D CG  1 
ATOM   7750 C  CD1 . TYR D 2 110 ? -33.965 -15.518 55.365  1   76.03  ? 280 TYR D CD1 1 
ATOM   7751 C  CD2 . TYR D 2 110 ? -32.157 -14.462 56.534  1   81.58  ? 280 TYR D CD2 1 
ATOM   7752 C  CE1 . TYR D 2 110 ? -34.316 -16.206 56.518  1   78     ? 280 TYR D CE1 1 
ATOM   7753 C  CE2 . TYR D 2 110 ? -32.508 -15.135 57.694  1   85.43  ? 280 TYR D CE2 1 
ATOM   7754 C  CZ  . TYR D 2 110 ? -33.585 -16.009 57.68   1   86.15  ? 280 TYR D CZ  1 
ATOM   7755 O  OH  . TYR D 2 110 ? -33.904 -16.672 58.83   1   92.79  ? 280 TYR D OH  1 
ATOM   7756 N  N   . ILE D 2 111 ? -32.943 -15.818 51.591  1   48.61  ? 281 ILE D N   1 
ATOM   7757 C  CA  . ILE D 2 111 ? -33.613 -16.971 50.998  1   48.97  ? 281 ILE D CA  1 
ATOM   7758 C  C   . ILE D 2 111 ? -32.637 -17.984 50.372  1   50.76  ? 281 ILE D C   1 
ATOM   7759 O  O   . ILE D 2 111 ? -33.018 -19.135 50.172  1   56.93  ? 281 ILE D O   1 
ATOM   7760 C  CB  . ILE D 2 111 ? -34.69  -16.545 49.984  1   48.24  ? 281 ILE D CB  1 
ATOM   7761 C  CG1 . ILE D 2 111 ? -34.096 -15.607 48.928  1   50.32  ? 281 ILE D CG1 1 
ATOM   7762 C  CG2 . ILE D 2 111 ? -35.924 -15.956 50.677  1   45.97  ? 281 ILE D CG2 1 
ATOM   7763 C  CD1 . ILE D 2 111 ? -34.88  -15.516 47.632  1   52.34  ? 281 ILE D CD1 1 
ATOM   7764 N  N   . THR D 2 112 ? -31.41  -17.585 50.007  1   47.99  ? 282 THR D N   1 
ATOM   7765 C  CA  . THR D 2 112 ? -30.466 -18.551 49.456  1   50.05  ? 282 THR D CA  1 
ATOM   7766 C  C   . THR D 2 112 ? -29.653 -19.237 50.564  1   53.77  ? 282 THR D C   1 
ATOM   7767 O  O   . THR D 2 112 ? -28.654 -19.902 50.267  1   51.38  ? 282 THR D O   1 
ATOM   7768 C  CB  . THR D 2 112 ? -29.527 -17.905 48.434  1   48.27  ? 282 THR D CB  1 
ATOM   7769 O  OG1 . THR D 2 112 ? -28.681 -17.042 49.194  1   54.59  ? 282 THR D OG1 1 
ATOM   7770 C  CG2 . THR D 2 112 ? -30.229 -17.173 47.311  1   40.51  ? 282 THR D CG2 1 
ATOM   7771 N  N   . ASP D 2 113 ? -30.059 -19.047 51.834  1   62.09  ? 283 ASP D N   1 
ATOM   7772 C  CA  . ASP D 2 113 ? -29.469 -19.697 53.005  1   67.24  ? 283 ASP D CA  1 
ATOM   7773 C  C   . ASP D 2 113 ? -27.965 -19.474 52.979  1   66.41  ? 283 ASP D C   1 
ATOM   7774 O  O   . ASP D 2 113 ? -27.187 -20.412 53.159  1   60.77  ? 283 ASP D O   1 
ATOM   7775 C  CB  . ASP D 2 113 ? -29.831 -21.174 53.126  1   76.04  ? 283 ASP D CB  1 
ATOM   7776 C  CG  . ASP D 2 113 ? -31.323 -21.51  53.108  1   87.9   ? 283 ASP D CG  1 
ATOM   7777 O  OD1 . ASP D 2 113 ? -32.076 -20.929 53.936  1   91.05  ? 283 ASP D OD1 1 
ATOM   7778 O  OD2 . ASP D 2 113 ? -31.735 -22.356 52.268  1   84.79  ? 283 ASP D OD2 1 
ATOM   7779 N  N   . ASP D 2 114 ? -27.604 -18.22  52.681  1   69.7   ? 284 ASP D N   1 
ATOM   7780 C  CA  . ASP D 2 114 ? -26.226 -17.756 52.598  1   75.05  ? 284 ASP D CA  1 
ATOM   7781 C  C   . ASP D 2 114 ? -25.384 -18.668 51.691  1   68.82  ? 284 ASP D C   1 
ATOM   7782 O  O   . ASP D 2 114 ? -24.18  -18.775 51.886  1   63.07  ? 284 ASP D O   1 
ATOM   7783 C  CB  . ASP D 2 114 ? -25.686 -17.451 53.993  1   93.14  ? 284 ASP D CB  1 
ATOM   7784 C  CG  . ASP D 2 114 ? -26.524 -16.504 54.855  1   97.6   ? 284 ASP D CG  1 
ATOM   7785 O  OD1 . ASP D 2 114 ? -27.543 -15.962 54.354  1   96.78  ? 284 ASP D OD1 1 
ATOM   7786 O  OD2 . ASP D 2 114 ? -26.166 -16.318 56.037  1   98.51  ? 284 ASP D OD2 1 
ATOM   7787 N  N   . THR D 2 115 ? -26.012 -19.308 50.685  1   63.79  ? 285 THR D N   1 
ATOM   7788 C  CA  . THR D 2 115 ? -25.272 -19.928 49.597  1   59.12  ? 285 THR D CA  1 
ATOM   7789 C  C   . THR D 2 115 ? -24.429 -18.855 48.893  1   56.7   ? 285 THR D C   1 
ATOM   7790 O  O   . THR D 2 115 ? -23.294 -19.126 48.506  1   58.49  ? 285 THR D O   1 
ATOM   7791 C  CB  . THR D 2 115 ? -26.193 -20.666 48.615  1   59.48  ? 285 THR D CB  1 
ATOM   7792 O  OG1 . THR D 2 115 ? -27.073 -21.6   49.238  1   56.09  ? 285 THR D OG1 1 
ATOM   7793 C  CG2 . THR D 2 115 ? -25.404 -21.443 47.577  1   58.76  ? 285 THR D CG2 1 
ATOM   7794 N  N   . TYR D 2 116 ? -24.973 -17.631 48.755  1   51.16  ? 286 TYR D N   1 
ATOM   7795 C  CA  . TYR D 2 116 ? -24.315 -16.548 48.027  1   47.41  ? 286 TYR D CA  1 
ATOM   7796 C  C   . TYR D 2 116 ? -24.21  -15.291 48.894  1   47.31  ? 286 TYR D C   1 
ATOM   7797 O  O   . TYR D 2 116 ? -25.007 -15.113 49.807  1   50.73  ? 286 TYR D O   1 
ATOM   7798 C  CB  . TYR D 2 116 ? -25.155 -16.221 46.79   1   40.72  ? 286 TYR D CB  1 
ATOM   7799 C  CG  . TYR D 2 116 ? -25.479 -17.423 45.917  1   39.85  ? 286 TYR D CG  1 
ATOM   7800 C  CD1 . TYR D 2 116 ? -24.473 -18.099 45.225  1   38.99  ? 286 TYR D CD1 1 
ATOM   7801 C  CD2 . TYR D 2 116 ? -26.788 -17.879 45.76   1   37.99  ? 286 TYR D CD2 1 
ATOM   7802 C  CE1 . TYR D 2 116 ? -24.75  -19.204 44.434  1   35.98  ? 286 TYR D CE1 1 
ATOM   7803 C  CE2 . TYR D 2 116 ? -27.073 -18.995 44.979  1   36.82  ? 286 TYR D CE2 1 
ATOM   7804 C  CZ  . TYR D 2 116 ? -26.053 -19.652 44.302  1   36.32  ? 286 TYR D CZ  1 
ATOM   7805 O  OH  . TYR D 2 116 ? -26.334 -20.705 43.469  1   33.49  ? 286 TYR D OH  1 
ATOM   7806 N  N   . THR D 2 117 ? -23.224 -14.423 48.589  1   47.64  ? 287 THR D N   1 
ATOM   7807 C  CA  . THR D 2 117 ? -23.048 -13.092 49.175  1   47.2   ? 287 THR D CA  1 
ATOM   7808 C  C   . THR D 2 117 ? -24.038 -12.083 48.584  1   46.69  ? 287 THR D C   1 
ATOM   7809 O  O   . THR D 2 117 ? -24.501 -12.209 47.452  1   45.7   ? 287 THR D O   1 
ATOM   7810 C  CB  . THR D 2 117 ? -21.641 -12.575 48.88   1   48.76  ? 287 THR D CB  1 
ATOM   7811 O  OG1 . THR D 2 117 ? -20.737 -13.6   49.259  1   47.74  ? 287 THR D OG1 1 
ATOM   7812 C  CG2 . THR D 2 117 ? -21.293 -11.345 49.7    1   54.39  ? 287 THR D CG2 1 
ATOM   7813 N  N   . LYS D 2 118 ? -24.286 -11.006 49.32   1   46.91  ? 288 LYS D N   1 
ATOM   7814 C  CA  . LYS D 2 118 ? -24.99  -9.864  48.766  1   45.93  ? 288 LYS D CA  1 
ATOM   7815 C  C   . LYS D 2 118 ? -24.265 -9.342  47.522  1   46.56  ? 288 LYS D C   1 
ATOM   7816 O  O   . LYS D 2 118 ? -24.916 -9.069  46.521  1   45.93  ? 288 LYS D O   1 
ATOM   7817 C  CB  . LYS D 2 118 ? -25.133 -8.828  49.879  1   47.66  ? 288 LYS D CB  1 
ATOM   7818 C  CG  . LYS D 2 118 ? -26.094 -7.685  49.642  1   49.3   ? 288 LYS D CG  1 
ATOM   7819 C  CD  . LYS D 2 118 ? -25.983 -6.805  50.885  1   54.4   ? 288 LYS D CD  1 
ATOM   7820 C  CE  . LYS D 2 118 ? -27.163 -5.893  51.05   1   57.72  ? 288 LYS D CE  1 
ATOM   7821 N  NZ  . LYS D 2 118 ? -26.97  -5.019  52.208  1   58.44  ? 288 LYS D NZ  1 
ATOM   7822 N  N   . LYS D 2 119 ? -22.929 -9.2    47.576  1   47.65  ? 289 LYS D N   1 
ATOM   7823 C  CA  . LYS D 2 119 ? -22.148 -8.747  46.435  1   46.74  ? 289 LYS D CA  1 
ATOM   7824 C  C   . LYS D 2 119 ? -22.404 -9.643  45.223  1   43.81  ? 289 LYS D C   1 
ATOM   7825 O  O   . LYS D 2 119 ? -22.599 -9.146  44.123  1   43.32  ? 289 LYS D O   1 
ATOM   7826 C  CB  . LYS D 2 119 ? -20.642 -8.701  46.691  1   52.26  ? 289 LYS D CB  1 
ATOM   7827 C  CG  . LYS D 2 119 ? -19.887 -7.72   45.787  1   60.23  ? 289 LYS D CG  1 
ATOM   7828 C  CD  . LYS D 2 119 ? -18.497 -7.324  46.286  1   66.41  ? 289 LYS D CD  1 
ATOM   7829 C  CE  . LYS D 2 119 ? -17.551 -8.489  46.423  1   63.98  ? 289 LYS D CE  1 
ATOM   7830 N  NZ  . LYS D 2 119 ? -16.367 -8.107  47.187  1   63.02  ? 289 LYS D NZ  1 
ATOM   7831 N  N   . GLN D 2 120 ? -22.441 -10.962 45.414  1   41.62  ? 290 GLN D N   1 
ATOM   7832 C  CA  . GLN D 2 120 ? -22.724 -11.866 44.309  1   37.97  ? 290 GLN D CA  1 
ATOM   7833 C  C   . GLN D 2 120 ? -24.131 -11.656 43.773  1   35.72  ? 290 GLN D C   1 
ATOM   7834 O  O   . GLN D 2 120 ? -24.359 -11.805 42.585  1   36.55  ? 290 GLN D O   1 
ATOM   7835 C  CB  . GLN D 2 120 ? -22.613 -13.347 44.653  1   37.52  ? 290 GLN D CB  1 
ATOM   7836 C  CG  . GLN D 2 120 ? -21.182 -13.863 44.635  1   39.42  ? 290 GLN D CG  1 
ATOM   7837 C  CD  . GLN D 2 120 ? -21.023 -15.018 45.593  1   42.7   ? 290 GLN D CD  1 
ATOM   7838 O  OE1 . GLN D 2 120 ? -21.257 -14.867 46.798  1   45.58  ? 290 GLN D OE1 1 
ATOM   7839 N  NE2 . GLN D 2 120 ? -20.692 -16.187 45.066  1   40.9   ? 290 GLN D NE2 1 
ATOM   7840 N  N   . VAL D 2 121 ? -25.08  -11.326 44.637  1   36.66  ? 291 VAL D N   1 
ATOM   7841 C  CA  . VAL D 2 121 ? -26.432 -11.122 44.162  1   34.86  ? 291 VAL D CA  1 
ATOM   7842 C  C   . VAL D 2 121 ? -26.459 -9.844  43.327  1   34.65  ? 291 VAL D C   1 
ATOM   7843 O  O   . VAL D 2 121 ? -26.954 -9.861  42.211  1   32.95  ? 291 VAL D O   1 
ATOM   7844 C  CB  . VAL D 2 121 ? -27.491 -11.146 45.278  1   36.7   ? 291 VAL D CB  1 
ATOM   7845 C  CG1 . VAL D 2 121 ? -28.87  -10.751 44.736  1   34.84  ? 291 VAL D CG1 1 
ATOM   7846 C  CG2 . VAL D 2 121 ? -27.531 -12.503 45.992  1   34.38  ? 291 VAL D CG2 1 
ATOM   7847 N  N   . LEU D 2 122 ? -25.858 -8.764  43.831  1   36.52  ? 292 LEU D N   1 
ATOM   7848 C  CA  . LEU D 2 122 ? -25.864 -7.486  43.13   1   38.2   ? 292 LEU D CA  1 
ATOM   7849 C  C   . LEU D 2 122 ? -25.092 -7.554  41.815  1   36.67  ? 292 LEU D C   1 
ATOM   7850 O  O   . LEU D 2 122 ? -25.588 -7.08   40.792  1   38.45  ? 292 LEU D O   1 
ATOM   7851 C  CB  . LEU D 2 122 ? -25.358 -6.396  44.07   1   40.8   ? 292 LEU D CB  1 
ATOM   7852 C  CG  . LEU D 2 122 ? -26.299 -6.142  45.251  1   42.55  ? 292 LEU D CG  1 
ATOM   7853 C  CD1 . LEU D 2 122 ? -25.804 -5.058  46.155  1   46.56  ? 292 LEU D CD1 1 
ATOM   7854 C  CD2 . LEU D 2 122 ? -27.684 -5.812  44.684  1   42.42  ? 292 LEU D CD2 1 
ATOM   7855 N  N   . ARG D 2 123 ? -23.948 -8.235  41.829  1   34.69  ? 293 ARG D N   1 
ATOM   7856 C  CA  . ARG D 2 123 ? -23.184 -8.43   40.61   1   36.24  ? 293 ARG D CA  1 
ATOM   7857 C  C   . ARG D 2 123 ? -23.958 -9.224  39.548  1   34.44  ? 293 ARG D C   1 
ATOM   7858 O  O   . ARG D 2 123 ? -23.941 -8.864  38.365  1   31.93  ? 293 ARG D O   1 
ATOM   7859 C  CB  . ARG D 2 123 ? -21.801 -9.008  40.9    1   38.87  ? 293 ARG D CB  1 
ATOM   7860 C  CG  . ARG D 2 123 ? -20.868 -7.949  41.475  1   42.12  ? 293 ARG D CG  1 
ATOM   7861 C  CD  . ARG D 2 123 ? -19.45  -8.267  41.041  1   49.66  ? 293 ARG D CD  1 
ATOM   7862 N  NE  . ARG D 2 123 ? -18.446 -8.024  42.083  1   63.63  ? 293 ARG D NE  1 
ATOM   7863 C  CZ  . ARG D 2 123 ? -17.696 -6.918  42.15   1   74.41  ? 293 ARG D CZ  1 
ATOM   7864 N  NH1 . ARG D 2 123 ? -18.066 -5.874  41.419  1   75.6   ? 293 ARG D NH1 1 
ATOM   7865 N  NH2 . ARG D 2 123 ? -16.628 -6.852  42.954  1   65.19  ? 293 ARG D NH2 1 
ATOM   7866 N  N   . MET D 2 124 ? -24.657 -10.285 39.974  1   33     ? 294 MET D N   1 
ATOM   7867 C  CA  . MET D 2 124 ? -25.478 -11.065 39.063  1   31.61  ? 294 MET D CA  1 
ATOM   7868 C  C   . MET D 2 124 ? -26.584 -10.181 38.489  1   31.05  ? 294 MET D C   1 
ATOM   7869 O  O   . MET D 2 124 ? -26.875 -10.263 37.291  1   33.97  ? 294 MET D O   1 
ATOM   7870 C  CB  . MET D 2 124 ? -26.113 -12.252 39.78   1   29.36  ? 294 MET D CB  1 
ATOM   7871 C  CG  . MET D 2 124 ? -26.706 -13.334 38.851  1   30.7   ? 294 MET D CG  1 
ATOM   7872 S  SD  . MET D 2 124 ? -25.935 -13.785 37.276  1   31.27  ? 294 MET D SD  1 
ATOM   7873 C  CE  . MET D 2 124 ? -25.015 -15.244 37.766  1   29.19  ? 294 MET D CE  1 
ATOM   7874 N  N   . GLU D 2 125 ? -27.141 -9.293  39.329  1   30.29  ? 295 GLU D N   1 
ATOM   7875 C  CA  . GLU D 2 125 ? -28.232 -8.431  38.903  1   32.06  ? 295 GLU D CA  1 
ATOM   7876 C  C   . GLU D 2 125 ? -27.741 -7.595  37.726  1   33.8   ? 295 GLU D C   1 
ATOM   7877 O  O   . GLU D 2 125 ? -28.442 -7.489  36.711  1   32.69  ? 295 GLU D O   1 
ATOM   7878 C  CB  . GLU D 2 125 ? -28.867 -7.621  40.04   1   32.42  ? 295 GLU D CB  1 
ATOM   7879 C  CG  . GLU D 2 125 ? -29.648 -6.404  39.56   1   32.22  ? 295 GLU D CG  1 
ATOM   7880 C  CD  . GLU D 2 125 ? -30.079 -5.445  40.647  1   35.23  ? 295 GLU D CD  1 
ATOM   7881 O  OE1 . GLU D 2 125 ? -29.23  -4.637  41.096  1   38.27  ? 295 GLU D OE1 1 
ATOM   7882 O  OE2 . GLU D 2 125 ? -31.25  -5.51   41.085  1   36.06  ? 295 GLU D OE2 1 
ATOM   7883 N  N   . HIS D 2 126 ? -26.532 -7.045  37.897  1   34.55  ? 296 HIS D N   1 
ATOM   7884 C  CA  . HIS D 2 126 ? -25.846 -6.308  36.851  1   40.59  ? 296 HIS D CA  1 
ATOM   7885 C  C   . HIS D 2 126 ? -25.715 -7.197  35.609  1   39.09  ? 296 HIS D C   1 
ATOM   7886 O  O   . HIS D 2 126 ? -26.049 -6.773  34.508  1   37.1   ? 296 HIS D O   1 
ATOM   7887 C  CB  . HIS D 2 126 ? -24.471 -5.804  37.314  1   49.55  ? 296 HIS D CB  1 
ATOM   7888 C  CG  . HIS D 2 126 ? -24.291 -4.388  37.846  1   76.08  ? 296 HIS D CG  1 
ATOM   7889 N  ND1 . HIS D 2 126 ? -23.015 -3.898  38.096  1   91.13  ? 296 HIS D ND1 1 
ATOM   7890 C  CD2 . HIS D 2 126 ? -25.115 -3.384  38.25   1   86.19  ? 296 HIS D CD2 1 
ATOM   7891 C  CE1 . HIS D 2 126 ? -23.066 -2.66   38.597  1   83.01  ? 296 HIS D CE1 1 
ATOM   7892 N  NE2 . HIS D 2 126 ? -24.331 -2.322  38.69   1   84.63  ? 296 HIS D NE2 1 
ATOM   7893 N  N   . LEU D 2 127 ? -25.209 -8.425  35.783  1   37.36  ? 297 LEU D N   1 
ATOM   7894 C  CA  . LEU D 2 127 ? -24.927 -9.283  34.653  1   36.46  ? 297 LEU D CA  1 
ATOM   7895 C  C   . LEU D 2 127 ? -26.235 -9.571  33.94   1   35.8   ? 297 LEU D C   1 
ATOM   7896 O  O   . LEU D 2 127 ? -26.261 -9.621  32.714  1   39.67  ? 297 LEU D O   1 
ATOM   7897 C  CB  . LEU D 2 127 ? -24.237 -10.596 35.013  1   37.32  ? 297 LEU D CB  1 
ATOM   7898 C  CG  . LEU D 2 127 ? -23.83  -11.491 33.827  1   34.52  ? 297 LEU D CG  1 
ATOM   7899 C  CD1 . LEU D 2 127 ? -22.912 -10.815 32.826  1   33.3   ? 297 LEU D CD1 1 
ATOM   7900 C  CD2 . LEU D 2 127 ? -23.225 -12.802 34.366  1   34.55  ? 297 LEU D CD2 1 
ATOM   7901 N  N   . VAL D 2 128 ? -27.296 -9.785  34.722  1   33.6   ? 298 VAL D N   1 
ATOM   7902 C  CA  . VAL D 2 128 ? -28.571 -10.158 34.133  1   34.2   ? 298 VAL D CA  1 
ATOM   7903 C  C   . VAL D 2 128 ? -29.099 -9.009  33.267  1   35.37  ? 298 VAL D C   1 
ATOM   7904 O  O   . VAL D 2 128 ? -29.626 -9.24   32.173  1   35.98  ? 298 VAL D O   1 
ATOM   7905 C  CB  . VAL D 2 128 ? -29.648 -10.65  35.115  1   31.51  ? 298 VAL D CB  1 
ATOM   7906 C  CG1 . VAL D 2 128 ? -30.999 -10.786 34.417  1   32.1   ? 298 VAL D CG1 1 
ATOM   7907 C  CG2 . VAL D 2 128 ? -29.262 -11.962 35.776  1   28.62  ? 298 VAL D CG2 1 
ATOM   7908 N  N   . LEU D 2 129 ? -28.973 -7.779  33.778  1   35.21  ? 299 LEU D N   1 
ATOM   7909 C  CA  . LEU D 2 129 ? -29.417 -6.59   33.065  1   35.05  ? 299 LEU D CA  1 
ATOM   7910 C  C   . LEU D 2 129 ? -28.661 -6.44   31.746  1   37.55  ? 299 LEU D C   1 
ATOM   7911 O  O   . LEU D 2 129 ? -29.267 -6.119  30.726  1   38.94  ? 299 LEU D O   1 
ATOM   7912 C  CB  . LEU D 2 129 ? -29.358 -5.337  33.934  1   33.02  ? 299 LEU D CB  1 
ATOM   7913 C  CG  . LEU D 2 129 ? -30.424 -5.247  35.033  1   32.3   ? 299 LEU D CG  1 
ATOM   7914 C  CD1 . LEU D 2 129 ? -30.024 -4.253  36.104  1   30.12  ? 299 LEU D CD1 1 
ATOM   7915 C  CD2 . LEU D 2 129 ? -31.787 -4.872  34.443  1   31.07  ? 299 LEU D CD2 1 
ATOM   7916 N  N   . LYS D 2 130 ? -27.357 -6.718  31.774  1   37.32  ? 300 LYS D N   1 
ATOM   7917 C  CA  . LYS D 2 130 ? -26.518 -6.594  30.596  1   40.86  ? 300 LYS D CA  1 
ATOM   7918 C  C   . LYS D 2 130 ? -26.898 -7.641  29.542  1   39.27  ? 300 LYS D C   1 
ATOM   7919 O  O   . LYS D 2 130 ? -26.919 -7.373  28.339  1   37.93  ? 300 LYS D O   1 
ATOM   7920 C  CB  . LYS D 2 130 ? -25.033 -6.781  30.917  1   46.77  ? 300 LYS D CB  1 
ATOM   7921 C  CG  . LYS D 2 130 ? -24.34  -5.707  31.766  1   56.02  ? 300 LYS D CG  1 
ATOM   7922 C  CD  . LYS D 2 130 ? -22.921 -5.338  31.314  1   70.05  ? 300 LYS D CD  1 
ATOM   7923 C  CE  . LYS D 2 130 ? -21.932 -5.015  32.412  1   75.83  ? 300 LYS D CE  1 
ATOM   7924 N  NZ  . LYS D 2 130 ? -21.608 -6.178  33.255  1   75.14  ? 300 LYS D NZ  1 
ATOM   7925 N  N   . VAL D 2 131 ? -27.174 -8.851  29.988  1   36.04  ? 301 VAL D N   1 
ATOM   7926 C  CA  . VAL D 2 131 ? -27.398 -9.896  29.014  1   39.07  ? 301 VAL D CA  1 
ATOM   7927 C  C   . VAL D 2 131 ? -28.753 -9.71   28.33   1   41.71  ? 301 VAL D C   1 
ATOM   7928 O  O   . VAL D 2 131 ? -28.862 -9.943  27.129  1   45.2   ? 301 VAL D O   1 
ATOM   7929 C  CB  . VAL D 2 131 ? -27.261 -11.288 29.635  1   38.75  ? 301 VAL D CB  1 
ATOM   7930 C  CG1 . VAL D 2 131 ? -27.935 -12.335 28.763  1   38.74  ? 301 VAL D CG1 1 
ATOM   7931 C  CG2 . VAL D 2 131 ? -25.798 -11.62  29.897  1   37.84  ? 301 VAL D CG2 1 
ATOM   7932 N  N   . LEU D 2 132 ? -29.756 -9.248  29.086  1   40.74  ? 302 LEU D N   1 
ATOM   7933 C  CA  . LEU D 2 132 ? -31.074 -8.926  28.566  1   35.8   ? 302 LEU D CA  1 
ATOM   7934 C  C   . LEU D 2 132 ? -31.104 -7.531  27.968  1   36.56  ? 302 LEU D C   1 
ATOM   7935 O  O   . LEU D 2 132 ? -32.106 -7.158  27.391  1   39.68  ? 302 LEU D O   1 
ATOM   7936 C  CB  . LEU D 2 132 ? -32.085 -9.035  29.699  1   34.62  ? 302 LEU D CB  1 
ATOM   7937 C  CG  . LEU D 2 132 ? -32.106 -10.394 30.404  1   33.56  ? 302 LEU D CG  1 
ATOM   7938 C  CD1 . LEU D 2 132 ? -33.152 -10.382 31.511  1   32.73  ? 302 LEU D CD1 1 
ATOM   7939 C  CD2 . LEU D 2 132 ? -32.362 -11.534 29.409  1   32.44  ? 302 LEU D CD2 1 
ATOM   7940 N  N   . ALA D 2 133 ? -30.025 -6.754  28.096  1   38.63  ? 303 ALA D N   1 
ATOM   7941 C  CA  . ALA D 2 133 ? -30     -5.397  27.561  1   39.68  ? 303 ALA D CA  1 
ATOM   7942 C  C   . ALA D 2 133 ? -31.169 -4.575  28.133  1   41.46  ? 303 ALA D C   1 
ATOM   7943 O  O   . ALA D 2 133 ? -31.768 -3.767  27.427  1   43.49  ? 303 ALA D O   1 
ATOM   7944 C  CB  . ALA D 2 133 ? -30.002 -5.462  26.041  1   37.77  ? 303 ALA D CB  1 
ATOM   7945 N  N   . PHE D 2 134 ? -31.505 -4.819  29.414  1   40.9   ? 304 PHE D N   1 
ATOM   7946 C  CA  . PHE D 2 134 ? -32.538 -4.142  30.178  1   39.58  ? 304 PHE D CA  1 
ATOM   7947 C  C   . PHE D 2 134 ? -33.922 -4.299  29.562  1   42.98  ? 304 PHE D C   1 
ATOM   7948 O  O   . PHE D 2 134 ? -34.774 -3.479  29.874  1   46.78  ? 304 PHE D O   1 
ATOM   7949 C  CB  . PHE D 2 134 ? -32.293 -2.638  30.295  1   41.98  ? 304 PHE D CB  1 
ATOM   7950 C  CG  . PHE D 2 134 ? -31.08  -2.21   31.119  1   48.41  ? 304 PHE D CG  1 
ATOM   7951 C  CD1 . PHE D 2 134 ? -29.78  -2.327  30.612  1   46.51  ? 304 PHE D CD1 1 
ATOM   7952 C  CD2 . PHE D 2 134 ? -31.239 -1.654  32.398  1   48.22  ? 304 PHE D CD2 1 
ATOM   7953 C  CE1 . PHE D 2 134 ? -28.68  -1.929  31.375  1   50.27  ? 304 PHE D CE1 1 
ATOM   7954 C  CE2 . PHE D 2 134 ? -30.132 -1.244  33.142  1   46.99  ? 304 PHE D CE2 1 
ATOM   7955 C  CZ  . PHE D 2 134 ? -28.852 -1.383  32.637  1   45.53  ? 304 PHE D CZ  1 
ATOM   7956 N  N   . ASP D 2 135 ? -34.164 -5.313  28.71   1   45.07  ? 305 ASP D N   1 
ATOM   7957 C  CA  . ASP D 2 135 ? -35.502 -5.534  28.161  1   47.36  ? 305 ASP D CA  1 
ATOM   7958 C  C   . ASP D 2 135 ? -36.327 -6.323  29.17   1   46.72  ? 305 ASP D C   1 
ATOM   7959 O  O   . ASP D 2 135 ? -36.465 -7.545  29.049  1   46.83  ? 305 ASP D O   1 
ATOM   7960 C  CB  . ASP D 2 135 ? -35.523 -6.156  26.772  1   51.26  ? 305 ASP D CB  1 
ATOM   7961 C  CG  . ASP D 2 135 ? -34.647 -5.463  25.733  1   66.03  ? 305 ASP D CG  1 
ATOM   7962 O  OD1 . ASP D 2 135 ? -34.667 -4.209  25.661  1   68.3   ? 305 ASP D OD1 1 
ATOM   7963 O  OD2 . ASP D 2 135 ? -33.939 -6.181  24.99   1   74.98  ? 305 ASP D OD2 1 
ATOM   7964 N  N   . LEU D 2 136 ? -36.863 -5.614  30.168  1   41.69  ? 306 LEU D N   1 
ATOM   7965 C  CA  . LEU D 2 136 ? -37.46  -6.315  31.287  1   40.39  ? 306 LEU D CA  1 
ATOM   7966 C  C   . LEU D 2 136 ? -38.978 -6.415  31.14   1   38.48  ? 306 LEU D C   1 
ATOM   7967 O  O   . LEU D 2 136 ? -39.595 -7.209  31.847  1   39.19  ? 306 LEU D O   1 
ATOM   7968 C  CB  . LEU D 2 136 ? -37.035 -5.688  32.621  1   46.66  ? 306 LEU D CB  1 
ATOM   7969 C  CG  . LEU D 2 136 ? -35.572 -5.849  33.072  1   49.02  ? 306 LEU D CG  1 
ATOM   7970 C  CD1 . LEU D 2 136 ? -35.564 -5.979  34.581  1   53.74  ? 306 LEU D CD1 1 
ATOM   7971 C  CD2 . LEU D 2 136 ? -34.77  -7.001  32.501  1   47.26  ? 306 LEU D CD2 1 
ATOM   7972 N  N   . ALA D 2 137 ? -39.581 -5.62   30.243  1   37.55  ? 307 ALA D N   1 
ATOM   7973 C  CA  . ALA D 2 137 ? -41.03  -5.559  30.162  1   38.6   ? 307 ALA D CA  1 
ATOM   7974 C  C   . ALA D 2 137 ? -41.56  -6.695  29.287  1   40.94  ? 307 ALA D C   1 
ATOM   7975 O  O   . ALA D 2 137 ? -42.137 -6.449  28.227  1   44.55  ? 307 ALA D O   1 
ATOM   7976 C  CB  . ALA D 2 137 ? -41.45  -4.197  29.667  1   39.29  ? 307 ALA D CB  1 
ATOM   7977 N  N   . ALA D 2 138 ? -41.346 -7.94   29.734  1   41.33  ? 308 ALA D N   1 
ATOM   7978 C  CA  . ALA D 2 138 ? -41.757 -9.147  29.015  1   44.75  ? 308 ALA D CA  1 
ATOM   7979 C  C   . ALA D 2 138 ? -43.256 -9.395  29.174  1   46.69  ? 308 ALA D C   1 
ATOM   7980 O  O   . ALA D 2 138 ? -43.767 -9.397  30.29   1   49.16  ? 308 ALA D O   1 
ATOM   7981 C  CB  . ALA D 2 138 ? -40.973 -10.36  29.493  1   41.48  ? 308 ALA D CB  1 
ATOM   7982 N  N   . PRO D 2 139 ? -44.022 -9.627  28.084  1   48.46  ? 309 PRO D N   1 
ATOM   7983 C  CA  . PRO D 2 139 ? -45.402 -10.088 28.234  1   51.48  ? 309 PRO D CA  1 
ATOM   7984 C  C   . PRO D 2 139 ? -45.398 -11.488 28.852  1   52.28  ? 309 PRO D C   1 
ATOM   7985 O  O   . PRO D 2 139 ? -44.514 -12.292 28.575  1   58.06  ? 309 PRO D O   1 
ATOM   7986 C  CB  . PRO D 2 139 ? -46.009 -10.043 26.817  1   52.12  ? 309 PRO D CB  1 
ATOM   7987 C  CG  . PRO D 2 139 ? -44.957 -9.371  25.963  1   50.4   ? 309 PRO D CG  1 
ATOM   7988 C  CD  . PRO D 2 139 ? -43.615 -9.474  26.68   1   48.55  ? 309 PRO D CD  1 
ATOM   7989 N  N   . THR D 2 140 ? -46.379 -11.758 29.718  1   52.84  ? 310 THR D N   1 
ATOM   7990 C  CA  . THR D 2 140 ? -46.432 -12.985 30.494  1   48.98  ? 310 THR D CA  1 
ATOM   7991 C  C   . THR D 2 140 ? -47.759 -13.687 30.238  1   50.75  ? 310 THR D C   1 
ATOM   7992 O  O   . THR D 2 140 ? -48.685 -13.137 29.64   1   47.39  ? 310 THR D O   1 
ATOM   7993 C  CB  . THR D 2 140 ? -46.286 -12.673 31.986  1   50.73  ? 310 THR D CB  1 
ATOM   7994 O  OG1 . THR D 2 140 ? -47.379 -11.851 32.394  1   48.79  ? 310 THR D OG1 1 
ATOM   7995 C  CG2 . THR D 2 140 ? -44.977 -11.985 32.332  1   49.3   ? 310 THR D CG2 1 
ATOM   7996 N  N   . ILE D 2 141 ? -47.845 -14.913 30.752  1   53.53  ? 311 ILE D N   1 
ATOM   7997 C  CA  . ILE D 2 141 ? -49.082 -15.67  30.7    1   54.33  ? 311 ILE D CA  1 
ATOM   7998 C  C   . ILE D 2 141 ? -50.186 -14.875 31.4    1   53.4   ? 311 ILE D C   1 
ATOM   7999 O  O   . ILE D 2 141 ? -51.296 -14.785 30.864  1   55.89  ? 311 ILE D O   1 
ATOM   8000 C  CB  . ILE D 2 141 ? -48.852 -17.08  31.282  1   51.79  ? 311 ILE D CB  1 
ATOM   8001 C  CG1 . ILE D 2 141 ? -48.089 -17.961 30.284  1   49.65  ? 311 ILE D CG1 1 
ATOM   8002 C  CG2 . ILE D 2 141 ? -50.157 -17.734 31.744  1   51.25  ? 311 ILE D CG2 1 
ATOM   8003 C  CD1 . ILE D 2 141 ? -47.445 -19.183 30.917  1   48.72  ? 311 ILE D CD1 1 
ATOM   8004 N  N   . ASN D 2 142 ? -49.861 -14.302 32.572  1   48.29  ? 312 ASN D N   1 
ATOM   8005 C  CA  . ASN D 2 142 ? -50.809 -13.548 33.381  1   51.79  ? 312 ASN D CA  1 
ATOM   8006 C  C   . ASN D 2 142 ? -51.371 -12.34  32.629  1   52.26  ? 312 ASN D C   1 
ATOM   8007 O  O   . ASN D 2 142 ? -52.524 -11.941 32.837  1   56.1   ? 312 ASN D O   1 
ATOM   8008 C  CB  . ASN D 2 142 ? -50.169 -12.992 34.646  1   55.38  ? 312 ASN D CB  1 
ATOM   8009 C  CG  . ASN D 2 142 ? -50.402 -13.89  35.829  1   65.54  ? 312 ASN D CG  1 
ATOM   8010 O  OD1 . ASN D 2 142 ? -50.221 -15.112 35.714  1   67.38  ? 312 ASN D OD1 1 
ATOM   8011 N  ND2 . ASN D 2 142 ? -50.854 -13.302 36.934  1   69.39  ? 312 ASN D ND2 1 
ATOM   8012 N  N   . GLN D 2 143 ? -50.533 -11.729 31.79   1   47.24  ? 313 GLN D N   1 
ATOM   8013 C  CA  . GLN D 2 143 ? -50.919 -10.516 31.106  1   48.4   ? 313 GLN D CA  1 
ATOM   8014 C  C   . GLN D 2 143 ? -51.99  -10.852 30.082  1   51.55  ? 313 GLN D C   1 
ATOM   8015 O  O   . GLN D 2 143 ? -52.874 -10.03  29.838  1   53.91  ? 313 GLN D O   1 
ATOM   8016 C  CB  . GLN D 2 143 ? -49.742 -9.781  30.47   1   46.94  ? 313 GLN D CB  1 
ATOM   8017 C  CG  . GLN D 2 143 ? -48.945 -8.982  31.492  1   45.67  ? 313 GLN D CG  1 
ATOM   8018 C  CD  . GLN D 2 143 ? -47.732 -8.35   30.858  1   47.46  ? 313 GLN D CD  1 
ATOM   8019 O  OE1 . GLN D 2 143 ? -47.829 -7.628  29.854  1   50.8   ? 313 GLN D OE1 1 
ATOM   8020 N  NE2 . GLN D 2 143 ? -46.572 -8.708  31.392  1   45.34  ? 313 GLN D NE2 1 
ATOM   8021 N  N   . PHE D 2 144 ? -51.908 -12.059 29.504  1   50.7   ? 314 PHE D N   1 
ATOM   8022 C  CA  . PHE D 2 144 ? -52.965 -12.502 28.608  1   50.99  ? 314 PHE D CA  1 
ATOM   8023 C  C   . PHE D 2 144 ? -54.219 -12.874 29.398  1   52.64  ? 314 PHE D C   1 
ATOM   8024 O  O   . PHE D 2 144 ? -55.289 -12.354 29.101  1   53.9   ? 314 PHE D O   1 
ATOM   8025 C  CB  . PHE D 2 144 ? -52.457 -13.536 27.609  1   50.02  ? 314 PHE D CB  1 
ATOM   8026 C  CG  . PHE D 2 144 ? -51.487 -12.902 26.629  1   49.34  ? 314 PHE D CG  1 
ATOM   8027 C  CD1 . PHE D 2 144 ? -51.953 -12.118 25.579  1   51.46  ? 314 PHE D CD1 1 
ATOM   8028 C  CD2 . PHE D 2 144 ? -50.117 -13.084 26.751  1   47.45  ? 314 PHE D CD2 1 
ATOM   8029 C  CE1 . PHE D 2 144 ? -51.072 -11.547 24.663  1   50.89  ? 314 PHE D CE1 1 
ATOM   8030 C  CE2 . PHE D 2 144 ? -49.243 -12.502 25.846  1   47.49  ? 314 PHE D CE2 1 
ATOM   8031 C  CZ  . PHE D 2 144 ? -49.723 -11.744 24.802  1   49.95  ? 314 PHE D CZ  1 
ATOM   8032 N  N   . LEU D 2 145 ? -54.059 -13.726 30.423  1   52.19  ? 315 LEU D N   1 
ATOM   8033 C  CA  . LEU D 2 145 ? -55.167 -14.223 31.229  1   54.78  ? 315 LEU D CA  1 
ATOM   8034 C  C   . LEU D 2 145 ? -56.068 -13.074 31.689  1   59.12  ? 315 LEU D C   1 
ATOM   8035 O  O   . LEU D 2 145 ? -57.301 -13.202 31.597  1   65.65  ? 315 LEU D O   1 
ATOM   8036 C  CB  . LEU D 2 145 ? -54.711 -15.048 32.436  1   52.88  ? 315 LEU D CB  1 
ATOM   8037 C  CG  . LEU D 2 145 ? -54.156 -16.45  32.157  1   53.83  ? 315 LEU D CG  1 
ATOM   8038 C  CD1 . LEU D 2 145 ? -53.576 -17.044 33.433  1   51.52  ? 315 LEU D CD1 1 
ATOM   8039 C  CD2 . LEU D 2 145 ? -55.198 -17.401 31.549  1   55.99  ? 315 LEU D CD2 1 
ATOM   8040 N  N   . THR D 2 146 ? -55.457 -11.983 32.208  1   52.62  ? 316 THR D N   1 
ATOM   8041 C  CA  . THR D 2 146 ? -56.23  -10.963 32.904  1   52.3   ? 316 THR D CA  1 
ATOM   8042 C  C   . THR D 2 146 ? -57.151 -10.284 31.898  1   54.18  ? 316 THR D C   1 
ATOM   8043 O  O   . THR D 2 146 ? -58.237 -9.806  32.253  1   56.13  ? 316 THR D O   1 
ATOM   8044 C  CB  . THR D 2 146 ? -55.384 -9.958  33.697  1   51.5   ? 316 THR D CB  1 
ATOM   8045 O  OG1 . THR D 2 146 ? -54.563 -9.233  32.784  1   49.35  ? 316 THR D OG1 1 
ATOM   8046 C  CG2 . THR D 2 146 ? -54.599 -10.583 34.842  1   49.56  ? 316 THR D CG2 1 
ATOM   8047 N  N   . GLN D 2 147 ? -56.71  -10.31  30.634  1   54.21  ? 317 GLN D N   1 
ATOM   8048 C  CA  . GLN D 2 147 ? -57.475 -9.784  29.516  1   57.33  ? 317 GLN D CA  1 
ATOM   8049 C  C   . GLN D 2 147 ? -58.573 -10.758 29.1    1   60.17  ? 317 GLN D C   1 
ATOM   8050 O  O   . GLN D 2 147 ? -59.708 -10.339 28.83   1   62.42  ? 317 GLN D O   1 
ATOM   8051 C  CB  . GLN D 2 147 ? -56.542 -9.58   28.329  1   57.24  ? 317 GLN D CB  1 
ATOM   8052 C  CG  . GLN D 2 147 ? -55.656 -8.348  28.433  1   59.86  ? 317 GLN D CG  1 
ATOM   8053 C  CD  . GLN D 2 147 ? -54.85  -8.124  27.174  1   64.03  ? 317 GLN D CD  1 
ATOM   8054 O  OE1 . GLN D 2 147 ? -53.62  -8.042  27.222  1   66.84  ? 317 GLN D OE1 1 
ATOM   8055 N  NE2 . GLN D 2 147 ? -55.526 -8.023  26.034  1   62.72  ? 317 GLN D NE2 1 
ATOM   8056 N  N   . TYR D 2 148 ? -58.211 -12.046 29.045  1   60.65  ? 318 TYR D N   1 
ATOM   8057 C  CA  . TYR D 2 148 ? -59.127 -13.104 28.64   1   63.23  ? 318 TYR D CA  1 
ATOM   8058 C  C   . TYR D 2 148 ? -60.284 -13.161 29.636  1   65.42  ? 318 TYR D C   1 
ATOM   8059 O  O   . TYR D 2 148 ? -61.424 -13.402 29.239  1   69.04  ? 318 TYR D O   1 
ATOM   8060 C  CB  . TYR D 2 148 ? -58.433 -14.47  28.522  1   60.64  ? 318 TYR D CB  1 
ATOM   8061 C  CG  . TYR D 2 148 ? -57.309 -14.63  27.5    1   57.32  ? 318 TYR D CG  1 
ATOM   8062 C  CD1 . TYR D 2 148 ? -57.123 -13.699 26.48   1   57.99  ? 318 TYR D CD1 1 
ATOM   8063 C  CD2 . TYR D 2 148 ? -56.425 -15.713 27.559  1   54.41  ? 318 TYR D CD2 1 
ATOM   8064 C  CE1 . TYR D 2 148 ? -56.098 -13.845 25.555  1   56.73  ? 318 TYR D CE1 1 
ATOM   8065 C  CE2 . TYR D 2 148 ? -55.414 -15.879 26.622  1   53.27  ? 318 TYR D CE2 1 
ATOM   8066 C  CZ  . TYR D 2 148 ? -55.246 -14.938 25.615  1   55.17  ? 318 TYR D CZ  1 
ATOM   8067 O  OH  . TYR D 2 148 ? -54.24  -15.033 24.684  1   55.22  ? 318 TYR D OH  1 
ATOM   8068 N  N   . PHE D 2 149 ? -59.978 -12.937 30.924  1   64.03  ? 319 PHE D N   1 
ATOM   8069 C  CA  . PHE D 2 149 ? -60.98  -12.982 31.977  1   67.32  ? 319 PHE D CA  1 
ATOM   8070 C  C   . PHE D 2 149 ? -62.099 -11.99  31.699  1   72.5   ? 319 PHE D C   1 
ATOM   8071 O  O   . PHE D 2 149 ? -63.247 -12.243 32.072  1   82.76  ? 319 PHE D O   1 
ATOM   8072 C  CB  . PHE D 2 149 ? -60.403 -12.712 33.36   1   66.79  ? 319 PHE D CB  1 
ATOM   8073 C  CG  . PHE D 2 149 ? -59.409 -13.762 33.838  1   68.87  ? 319 PHE D CG  1 
ATOM   8074 C  CD1 . PHE D 2 149 ? -59.488 -15.083 33.391  1   68.37  ? 319 PHE D CD1 1 
ATOM   8075 C  CD2 . PHE D 2 149 ? -58.401 -13.416 34.738  1   66.72  ? 319 PHE D CD2 1 
ATOM   8076 C  CE1 . PHE D 2 149 ? -58.594 -16.041 33.845  1   67.6   ? 319 PHE D CE1 1 
ATOM   8077 C  CE2 . PHE D 2 149 ? -57.506 -14.377 35.181  1   68     ? 319 PHE D CE2 1 
ATOM   8078 C  CZ  . PHE D 2 149 ? -57.602 -15.687 34.732  1   67.72  ? 319 PHE D CZ  1 
ATOM   8079 N  N   . LEU D 2 150 ? -61.762 -10.893 31.012  1   70.46  ? 320 LEU D N   1 
ATOM   8080 C  CA  . LEU D 2 150 ? -62.743 -9.852  30.734  1   74.59  ? 320 LEU D CA  1 
ATOM   8081 C  C   . LEU D 2 150 ? -63.825 -10.353 29.766  1   80.43  ? 320 LEU D C   1 
ATOM   8082 O  O   . LEU D 2 150 ? -64.721 -9.598  29.383  1   82.57  ? 320 LEU D O   1 
ATOM   8083 C  CB  . LEU D 2 150 ? -62.035 -8.597  30.224  1   69.67  ? 320 LEU D CB  1 
ATOM   8084 C  CG  . LEU D 2 150 ? -60.992 -8.01   31.178  1   68.32  ? 320 LEU D CG  1 
ATOM   8085 C  CD1 . LEU D 2 150 ? -60.126 -6.974  30.462  1   66.29  ? 320 LEU D CD1 1 
ATOM   8086 C  CD2 . LEU D 2 150 ? -61.633 -7.468  32.457  1   67.53  ? 320 LEU D CD2 1 
ATOM   8087 N  N   . HIS D 2 151 ? -63.749 -11.632 29.372  1   81.06  ? 321 HIS D N   1 
ATOM   8088 C  CA  . HIS D 2 151 ? -64.743 -12.189 28.471  1   83.84  ? 321 HIS D CA  1 
ATOM   8089 C  C   . HIS D 2 151 ? -65.519 -13.291 29.175  1   85.54  ? 321 HIS D C   1 
ATOM   8090 O  O   . HIS D 2 151 ? -66.209 -14.059 28.515  1   91.03  ? 321 HIS D O   1 
ATOM   8091 C  CB  . HIS D 2 151 ? -64.121 -12.735 27.182  1   83.88  ? 321 HIS D CB  1 
ATOM   8092 C  CG  . HIS D 2 151 ? -63.385 -11.735 26.358  1   83.62  ? 321 HIS D CG  1 
ATOM   8093 N  ND1 . HIS D 2 151 ? -63.563 -11.649 24.994  1   86.71  ? 321 HIS D ND1 1 
ATOM   8094 C  CD2 . HIS D 2 151 ? -62.483 -10.796 26.675  1   81.08  ? 321 HIS D CD2 1 
ATOM   8095 C  CE1 . HIS D 2 151 ? -62.787 -10.686 24.512  1   85.39  ? 321 HIS D CE1 1 
ATOM   8096 N  NE2 . HIS D 2 151 ? -62.117 -10.161 25.516  1   82.63  ? 321 HIS D NE2 1 
ATOM   8097 N  N   . GLN D 2 152 ? -65.423 -13.34  30.508  1   83.74  ? 322 GLN D N   1 
ATOM   8098 C  CA  . GLN D 2 152 ? -66.157 -14.328 31.279  1   88.87  ? 322 GLN D CA  1 
ATOM   8099 C  C   . GLN D 2 152 ? -67.646 -13.992 31.333  1   97.05  ? 322 GLN D C   1 
ATOM   8100 O  O   . GLN D 2 152 ? -68.006 -12.825 31.416  1   98.28  ? 322 GLN D O   1 
ATOM   8101 C  CB  . GLN D 2 152 ? -65.624 -14.439 32.701  1   85.88  ? 322 GLN D CB  1 
ATOM   8102 C  CG  . GLN D 2 152 ? -64.656 -15.595 32.919  1   85.92  ? 322 GLN D CG  1 
ATOM   8103 C  CD  . GLN D 2 152 ? -63.919 -15.472 34.231  1   88.78  ? 322 GLN D CD  1 
ATOM   8104 O  OE1 . GLN D 2 152 ? -63.771 -16.447 34.968  1   97.73  ? 322 GLN D OE1 1 
ATOM   8105 N  NE2 . GLN D 2 152 ? -63.401 -14.284 34.514  1   85.06  ? 322 GLN D NE2 1 
ATOM   8106 N  N   . GLN D 2 153 ? -68.491 -15.036 31.297  1   104.63 ? 323 GLN D N   1 
ATOM   8107 C  CA  . GLN D 2 153 ? -69.932 -14.878 31.406  1   114.22 ? 323 GLN D CA  1 
ATOM   8108 C  C   . GLN D 2 153 ? -70.511 -15.843 32.446  1   117.98 ? 323 GLN D C   1 
ATOM   8109 O  O   . GLN D 2 153 ? -70.729 -17.036 32.156  1   120.59 ? 323 GLN D O   1 
ATOM   8110 C  CB  . GLN D 2 153 ? -70.592 -14.973 30.03   1   121.52 ? 323 GLN D CB  1 
ATOM   8111 C  CG  . GLN D 2 153 ? -71.963 -14.31  29.972  1   135    ? 323 GLN D CG  1 
ATOM   8112 C  CD  . GLN D 2 153 ? -72.041 -13.07  30.836  1   134.92 ? 323 GLN D CD  1 
ATOM   8113 O  OE1 . GLN D 2 153 ? -71.39  -12.051 30.578  1   133.47 ? 323 GLN D OE1 1 
ATOM   8114 N  NE2 . GLN D 2 153 ? -72.829 -13.162 31.894  1   138.63 ? 323 GLN D NE2 1 
ATOM   8115 N  N   . PRO D 2 154 ? -70.705 -15.369 33.708  1   119.02 ? 324 PRO D N   1 
ATOM   8116 C  CA  . PRO D 2 154 ? -70.02  -14.168 34.213  1   116.11 ? 324 PRO D CA  1 
ATOM   8117 C  C   . PRO D 2 154 ? -68.668 -14.508 34.851  1   111.97 ? 324 PRO D C   1 
ATOM   8118 O  O   . PRO D 2 154 ? -68.194 -15.643 34.743  1   114.49 ? 324 PRO D O   1 
ATOM   8119 C  CB  . PRO D 2 154 ? -71.032 -13.637 35.235  1   112.53 ? 324 PRO D CB  1 
ATOM   8120 C  CG  . PRO D 2 154 ? -71.618 -14.901 35.824  1   115.59 ? 324 PRO D CG  1 
ATOM   8121 C  CD  . PRO D 2 154 ? -71.649 -15.927 34.693  1   118.02 ? 324 PRO D CD  1 
ATOM   8122 N  N   . ALA D 2 155 ? -68.05  -13.521 35.514  1   104.37 ? 325 ALA D N   1 
ATOM   8123 C  CA  . ALA D 2 155 ? -66.766 -13.725 36.17   1   96.28  ? 325 ALA D CA  1 
ATOM   8124 C  C   . ALA D 2 155 ? -66.889 -14.847 37.199  1   96.43  ? 325 ALA D C   1 
ATOM   8125 O  O   . ALA D 2 155 ? -67.816 -14.858 38.005  1   101.58 ? 325 ALA D O   1 
ATOM   8126 C  CB  . ALA D 2 155 ? -66.277 -12.432 36.786  1   92.94  ? 325 ALA D CB  1 
ATOM   8127 N  N   . ASN D 2 156 ? -65.966 -15.814 37.134  1   91.23  ? 326 ASN D N   1 
ATOM   8128 C  CA  . ASN D 2 156 ? -65.97  -16.943 38.054  1   90.2   ? 326 ASN D CA  1 
ATOM   8129 C  C   . ASN D 2 156 ? -64.577 -17.089 38.674  1   84.41  ? 326 ASN D C   1 
ATOM   8130 O  O   . ASN D 2 156 ? -63.588 -17.198 37.954  1   79.56  ? 326 ASN D O   1 
ATOM   8131 C  CB  . ASN D 2 156 ? -66.462 -18.203 37.346  1   93.71  ? 326 ASN D CB  1 
ATOM   8132 C  CG  . ASN D 2 156 ? -66.74  -19.34  38.3    1   98.4   ? 326 ASN D CG  1 
ATOM   8133 O  OD1 . ASN D 2 156 ? -66.032 -19.518 39.296  1   100.22 ? 326 ASN D OD1 1 
ATOM   8134 N  ND2 . ASN D 2 156 ? -67.783 -20.108 38.033  1   103.91 ? 326 ASN D ND2 1 
ATOM   8135 N  N   . CYS D 2 157 ? -64.497 -17.104 40.012  1   85.49  ? 327 CYS D N   1 
ATOM   8136 C  CA  . CYS D 2 157 ? -63.21  -17.015 40.699  1   86.71  ? 327 CYS D CA  1 
ATOM   8137 C  C   . CYS D 2 157 ? -62.631 -18.4   41.002  1   84.64  ? 327 CYS D C   1 
ATOM   8138 O  O   . CYS D 2 157 ? -61.476 -18.513 41.414  1   82.73  ? 327 CYS D O   1 
ATOM   8139 C  CB  . CYS D 2 157 ? -63.267 -16.126 41.94   1   93.23  ? 327 CYS D CB  1 
ATOM   8140 S  SG  . CYS D 2 157 ? -64.548 -16.612 43.125  1   109.23 ? 327 CYS D SG  1 
ATOM   8141 N  N   . LYS D 2 158 ? -63.437 -19.451 40.807  1   83.3   ? 328 LYS D N   1 
ATOM   8142 C  CA  . LYS D 2 158 ? -62.898 -20.793 40.657  1   79.22  ? 328 LYS D CA  1 
ATOM   8143 C  C   . LYS D 2 158 ? -62.179 -20.901 39.309  1   76.14  ? 328 LYS D C   1 
ATOM   8144 O  O   . LYS D 2 158 ? -61.073 -21.444 39.244  1   72.94  ? 328 LYS D O   1 
ATOM   8145 C  CB  . LYS D 2 158 ? -63.961 -21.876 40.882  1   82.53  ? 328 LYS D CB  1 
ATOM   8146 C  CG  . LYS D 2 158 ? -64.141 -22.213 42.36   1   84.59  ? 328 LYS D CG  1 
ATOM   8147 C  CD  . LYS D 2 158 ? -65.404 -22.963 42.77   1   86.05  ? 328 LYS D CD  1 
ATOM   8148 C  CE  . LYS D 2 158 ? -65.563 -22.991 44.264  1   85.76  ? 328 LYS D CE  1 
ATOM   8149 N  NZ  . LYS D 2 158 ? -66.798 -23.658 44.69   1   88.23  ? 328 LYS D NZ  1 
ATOM   8150 N  N   . VAL D 2 159 ? -62.814 -20.379 38.243  1   75.43  ? 329 VAL D N   1 
ATOM   8151 C  CA  . VAL D 2 159 ? -62.265 -20.407 36.896  1   70.75  ? 329 VAL D CA  1 
ATOM   8152 C  C   . VAL D 2 159 ? -60.954 -19.63  36.886  1   68.47  ? 329 VAL D C   1 
ATOM   8153 O  O   . VAL D 2 159 ? -59.916 -20.189 36.537  1   69.93  ? 329 VAL D O   1 
ATOM   8154 C  CB  . VAL D 2 159 ? -63.231 -19.898 35.813  1   70.75  ? 329 VAL D CB  1 
ATOM   8155 C  CG1 . VAL D 2 159 ? -62.561 -19.865 34.448  1   67.21  ? 329 VAL D CG1 1 
ATOM   8156 C  CG2 . VAL D 2 159 ? -64.518 -20.719 35.774  1   75.59  ? 329 VAL D CG2 1 
ATOM   8157 N  N   . GLU D 2 160 ? -61.013 -18.358 37.304  1   70.4   ? 330 GLU D N   1 
ATOM   8158 C  CA  . GLU D 2 160 ? -59.853 -17.473 37.379  1   67.37  ? 330 GLU D CA  1 
ATOM   8159 C  C   . GLU D 2 160 ? -58.696 -18.136 38.122  1   61.64  ? 330 GLU D C   1 
ATOM   8160 O  O   . GLU D 2 160 ? -57.64  -18.403 37.541  1   57.76  ? 330 GLU D O   1 
ATOM   8161 C  CB  . GLU D 2 160 ? -60.23  -16.144 38.03   1   70.47  ? 330 GLU D CB  1 
ATOM   8162 C  CG  . GLU D 2 160 ? -61.015 -15.239 37.083  1   81.44  ? 330 GLU D CG  1 
ATOM   8163 C  CD  . GLU D 2 160 ? -61.54  -13.962 37.717  1   87.41  ? 330 GLU D CD  1 
ATOM   8164 O  OE1 . GLU D 2 160 ? -61.385 -13.791 38.952  1   86.29  ? 330 GLU D OE1 1 
ATOM   8165 O  OE2 . GLU D 2 160 ? -62.129 -13.151 36.963  1   88.27  ? 330 GLU D OE2 1 
ATOM   8166 N  N   . SER D 2 161 ? -58.921 -18.405 39.41   1   60.39  ? 331 SER D N   1 
ATOM   8167 C  CA  . SER D 2 161 ? -57.957 -19.138 40.206  1   61.19  ? 331 SER D CA  1 
ATOM   8168 C  C   . SER D 2 161 ? -57.447 -20.376 39.467  1   61.75  ? 331 SER D C   1 
ATOM   8169 O  O   . SER D 2 161 ? -56.239 -20.572 39.407  1   62.98  ? 331 SER D O   1 
ATOM   8170 C  CB  . SER D 2 161 ? -58.482 -19.471 41.578  1   64.89  ? 331 SER D CB  1 
ATOM   8171 O  OG  . SER D 2 161 ? -58.451 -18.33  42.427  1   63.85  ? 331 SER D OG  1 
ATOM   8172 N  N   . LEU D 2 162 ? -58.342 -21.196 38.9    1   61.27  ? 332 LEU D N   1 
ATOM   8173 C  CA  . LEU D 2 162 ? -57.899 -22.419 38.253  1   60.42  ? 332 LEU D CA  1 
ATOM   8174 C  C   . LEU D 2 162 ? -57.041 -22.107 37.02   1   59.32  ? 332 LEU D C   1 
ATOM   8175 O  O   . LEU D 2 162 ? -56.091 -22.831 36.752  1   58.4   ? 332 LEU D O   1 
ATOM   8176 C  CB  . LEU D 2 162 ? -59.028 -23.401 37.942  1   64.69  ? 332 LEU D CB  1 
ATOM   8177 C  CG  . LEU D 2 162 ? -58.605 -24.766 37.371  1   68.18  ? 332 LEU D CG  1 
ATOM   8178 C  CD1 . LEU D 2 162 ? -57.587 -25.435 38.29   1   67.78  ? 332 LEU D CD1 1 
ATOM   8179 C  CD2 . LEU D 2 162 ? -59.763 -25.742 37.064  1   69.44  ? 332 LEU D CD2 1 
ATOM   8180 N  N   . ALA D 2 163 ? -57.356 -21.057 36.247  1   58.3   ? 333 ALA D N   1 
ATOM   8181 C  CA  . ALA D 2 163 ? -56.547 -20.777 35.068  1   55.29  ? 333 ALA D CA  1 
ATOM   8182 C  C   . ALA D 2 163 ? -55.169 -20.24  35.472  1   56.89  ? 333 ALA D C   1 
ATOM   8183 O  O   . ALA D 2 163 ? -54.168 -20.549 34.822  1   53.07  ? 333 ALA D O   1 
ATOM   8184 C  CB  . ALA D 2 163 ? -57.279 -19.871 34.111  1   52.71  ? 333 ALA D CB  1 
ATOM   8185 N  N   . MET D 2 164 ? -55.108 -19.47  36.573  1   59.62  ? 334 MET D N   1 
ATOM   8186 C  CA  . MET D 2 164 ? -53.837 -18.995 37.118  1   60.04  ? 334 MET D CA  1 
ATOM   8187 C  C   . MET D 2 164 ? -52.963 -20.186 37.513  1   59.08  ? 334 MET D C   1 
ATOM   8188 O  O   . MET D 2 164 ? -51.776 -20.215 37.189  1   58.2   ? 334 MET D O   1 
ATOM   8189 C  CB  . MET D 2 164 ? -54.026 -18.112 38.364  1   65.1   ? 334 MET D CB  1 
ATOM   8190 C  CG  . MET D 2 164 ? -54.559 -16.7   38.101  1   71.04  ? 334 MET D CG  1 
ATOM   8191 S  SD  . MET D 2 164 ? -53.347 -15.643 37.281  1   81.28  ? 334 MET D SD  1 
ATOM   8192 C  CE  . MET D 2 164 ? -54.168 -14.049 37.149  1   81.19  ? 334 MET D CE  1 
ATOM   8193 N  N   . PHE D 2 165 ? -53.573 -21.162 38.208  1   59.49  ? 335 PHE D N   1 
ATOM   8194 C  CA  . PHE D 2 165 ? -52.924 -22.395 38.633  1   56.76  ? 335 PHE D CA  1 
ATOM   8195 C  C   . PHE D 2 165 ? -52.309 -23.136 37.442  1   53.75  ? 335 PHE D C   1 
ATOM   8196 O  O   . PHE D 2 165 ? -51.117 -23.422 37.46   1   53.41  ? 335 PHE D O   1 
ATOM   8197 C  CB  . PHE D 2 165 ? -53.878 -23.263 39.453  1   58.14  ? 335 PHE D CB  1 
ATOM   8198 C  CG  . PHE D 2 165 ? -53.417 -24.702 39.631  1   60.66  ? 335 PHE D CG  1 
ATOM   8199 C  CD1 . PHE D 2 165 ? -52.39  -25.024 40.514  1   61.31  ? 335 PHE D CD1 1 
ATOM   8200 C  CD2 . PHE D 2 165 ? -54.022 -25.741 38.923  1   62.53  ? 335 PHE D CD2 1 
ATOM   8201 C  CE1 . PHE D 2 165 ? -51.97  -26.343 40.676  1   61.22  ? 335 PHE D CE1 1 
ATOM   8202 C  CE2 . PHE D 2 165 ? -53.616 -27.061 39.102  1   62.57  ? 335 PHE D CE2 1 
ATOM   8203 C  CZ  . PHE D 2 165 ? -52.599 -27.36  39.984  1   63.27  ? 335 PHE D CZ  1 
ATOM   8204 N  N   . LEU D 2 166 ? -53.104 -23.422 36.406  1   50.37  ? 336 LEU D N   1 
ATOM   8205 C  CA  . LEU D 2 166 ? -52.604 -24.173 35.264  1   49.92  ? 336 LEU D CA  1 
ATOM   8206 C  C   . LEU D 2 166 ? -51.449 -23.431 34.604  1   49.82  ? 336 LEU D C   1 
ATOM   8207 O  O   . LEU D 2 166 ? -50.418 -24.028 34.278  1   48.26  ? 336 LEU D O   1 
ATOM   8208 C  CB  . LEU D 2 166 ? -53.719 -24.466 34.266  1   51.33  ? 336 LEU D CB  1 
ATOM   8209 C  CG  . LEU D 2 166 ? -54.868 -25.317 34.812  1   53     ? 336 LEU D CG  1 
ATOM   8210 C  CD1 . LEU D 2 166 ? -55.911 -25.555 33.748  1   54.63  ? 336 LEU D CD1 1 
ATOM   8211 C  CD2 . LEU D 2 166 ? -54.333 -26.626 35.358  1   53.88  ? 336 LEU D CD2 1 
ATOM   8212 N  N   . GLY D 2 167 ? -51.639 -22.117 34.421  1   50.54  ? 337 GLY D N   1 
ATOM   8213 C  CA  . GLY D 2 167 ? -50.621 -21.247 33.859  1   48.6   ? 337 GLY D CA  1 
ATOM   8214 C  C   . GLY D 2 167 ? -49.263 -21.425 34.541  1   49.31  ? 337 GLY D C   1 
ATOM   8215 O  O   . GLY D 2 167 ? -48.251 -21.575 33.858  1   52.1   ? 337 GLY D O   1 
ATOM   8216 N  N   . GLU D 2 168 ? -49.253 -21.394 35.883  1   48.87  ? 338 GLU D N   1 
ATOM   8217 C  CA  . GLU D 2 168 ? -48.022 -21.435 36.657  1   44.87  ? 338 GLU D CA  1 
ATOM   8218 C  C   . GLU D 2 168 ? -47.379 -22.813 36.522  1   46.24  ? 338 GLU D C   1 
ATOM   8219 O  O   . GLU D 2 168 ? -46.154 -22.904 36.446  1   43.92  ? 338 GLU D O   1 
ATOM   8220 C  CB  . GLU D 2 168 ? -48.222 -21.224 38.153  1   44.88  ? 338 GLU D CB  1 
ATOM   8221 C  CG  . GLU D 2 168 ? -48.563 -19.791 38.535  1   48.65  ? 338 GLU D CG  1 
ATOM   8222 C  CD  . GLU D 2 168 ? -48.431 -19.499 40.027  1   51.23  ? 338 GLU D CD  1 
ATOM   8223 O  OE1 . GLU D 2 168 ? -47.718 -20.272 40.717  1   50.7   ? 338 GLU D OE1 1 
ATOM   8224 O  OE2 . GLU D 2 168 ? -49.052 -18.509 40.498  1   51.94  ? 338 GLU D OE2 1 
ATOM   8225 N  N   . LEU D 2 169 ? -48.216 -23.867 36.488  1   45.85  ? 339 LEU D N   1 
ATOM   8226 C  CA  . LEU D 2 169 ? -47.77  -25.234 36.293  1   45.46  ? 339 LEU D CA  1 
ATOM   8227 C  C   . LEU D 2 169 ? -46.836 -25.315 35.095  1   45.76  ? 339 LEU D C   1 
ATOM   8228 O  O   . LEU D 2 169 ? -45.816 -25.992 35.185  1   49.05  ? 339 LEU D O   1 
ATOM   8229 C  CB  . LEU D 2 169 ? -48.913 -26.239 36.175  1   48.6   ? 339 LEU D CB  1 
ATOM   8230 C  CG  . LEU D 2 169 ? -49.506 -26.744 37.498  1   51.6   ? 339 LEU D CG  1 
ATOM   8231 C  CD1 . LEU D 2 169 ? -50.438 -27.927 37.237  1   52.06  ? 339 LEU D CD1 1 
ATOM   8232 C  CD2 . LEU D 2 169 ? -48.403 -27.12  38.504  1   51.57  ? 339 LEU D CD2 1 
ATOM   8233 N  N   . SER D 2 170 ? -47.182 -24.608 34.007  1   44.16  ? 340 SER D N   1 
ATOM   8234 C  CA  . SER D 2 170 ? -46.407 -24.648 32.78   1   43.6   ? 340 SER D CA  1 
ATOM   8235 C  C   . SER D 2 170 ? -45.001 -24.062 32.968  1   47.34  ? 340 SER D C   1 
ATOM   8236 O  O   . SER D 2 170 ? -44.083 -24.461 32.241  1   50.39  ? 340 SER D O   1 
ATOM   8237 C  CB  . SER D 2 170 ? -47.141 -23.993 31.649  1   42.55  ? 340 SER D CB  1 
ATOM   8238 O  OG  . SER D 2 170 ? -47.191 -22.575 31.763  1   38.81  ? 340 SER D OG  1 
ATOM   8239 N  N   . LEU D 2 171 ? -44.814 -23.132 33.934  1   46.59  ? 341 LEU D N   1 
ATOM   8240 C  CA  . LEU D 2 171 ? -43.508 -22.522 34.212  1   42.97  ? 341 LEU D CA  1 
ATOM   8241 C  C   . LEU D 2 171 ? -42.475 -23.574 34.628  1   45.51  ? 341 LEU D C   1 
ATOM   8242 O  O   . LEU D 2 171 ? -41.275 -23.383 34.397  1   45.74  ? 341 LEU D O   1 
ATOM   8243 C  CB  . LEU D 2 171 ? -43.576 -21.438 35.291  1   41.07  ? 341 LEU D CB  1 
ATOM   8244 C  CG  . LEU D 2 171 ? -44.544 -20.265 35.07   1   40.69  ? 341 LEU D CG  1 
ATOM   8245 C  CD1 . LEU D 2 171 ? -44.62  -19.433 36.357  1   39.35  ? 341 LEU D CD1 1 
ATOM   8246 C  CD2 . LEU D 2 171 ? -44.136 -19.382 33.894  1   36.37  ? 341 LEU D CD2 1 
ATOM   8247 N  N   . ILE D 2 172 ? -42.932 -24.639 35.319  1   44.71  ? 342 ILE D N   1 
ATOM   8248 C  CA  . ILE D 2 172 ? -42.023 -25.617 35.896  1   44.77  ? 342 ILE D CA  1 
ATOM   8249 C  C   . ILE D 2 172 ? -41.29  -26.41  34.807  1   45.84  ? 342 ILE D C   1 
ATOM   8250 O  O   . ILE D 2 172 ? -40.096 -26.687 34.935  1   45.83  ? 342 ILE D O   1 
ATOM   8251 C  CB  . ILE D 2 172 ? -42.773 -26.559 36.847  1   46.28  ? 342 ILE D CB  1 
ATOM   8252 C  CG1 . ILE D 2 172 ? -43.414 -25.804 38.011  1   47.64  ? 342 ILE D CG1 1 
ATOM   8253 C  CG2 . ILE D 2 172 ? -41.829 -27.661 37.322  1   45.7   ? 342 ILE D CG2 1 
ATOM   8254 C  CD1 . ILE D 2 172 ? -42.474 -25.496 39.161  1   45.11  ? 342 ILE D CD1 1 
ATOM   8255 N  N   . ASP D 2 173 ? -42.035 -26.793 33.777  1   46.41  ? 343 ASP D N   1 
ATOM   8256 C  CA  . ASP D 2 173 ? -41.485 -27.727 32.765  1   46.53  ? 343 ASP D CA  1 
ATOM   8257 C  C   . ASP D 2 173 ? -41.114 -27.028 31.46   1   46.16  ? 343 ASP D C   1 
ATOM   8258 O  O   . ASP D 2 173 ? -42.022 -26.707 30.686  1   47.3   ? 343 ASP D O   1 
ATOM   8259 C  CB  . ASP D 2 173 ? -42.464 -28.878 32.612  1   46.88  ? 343 ASP D CB  1 
ATOM   8260 C  CG  . ASP D 2 173 ? -42.821 -29.591 33.905  1   50.9   ? 343 ASP D CG  1 
ATOM   8261 O  OD1 . ASP D 2 173 ? -41.896 -30.098 34.566  1   50.81  ? 343 ASP D OD1 1 
ATOM   8262 O  OD2 . ASP D 2 173 ? -44.018 -29.627 34.241  1   53.95  ? 343 ASP D OD2 1 
ATOM   8263 N  N   . ALA D 2 174 ? -39.817 -26.849 31.226  1   43.8   ? 344 ALA D N   1 
ATOM   8264 C  CA  . ALA D 2 174 ? -39.331 -26.25  29.969  1   43.86  ? 344 ALA D CA  1 
ATOM   8265 C  C   . ALA D 2 174 ? -39.826 -27.119 28.827  1   46.45  ? 344 ALA D C   1 
ATOM   8266 O  O   . ALA D 2 174 ? -40.224 -26.582 27.791  1   52.65  ? 344 ALA D O   1 
ATOM   8267 C  CB  . ALA D 2 174 ? -37.841 -26.19  30.013  1   42.29  ? 344 ALA D CB  1 
ATOM   8268 N  N   . ASP D 2 175 ? -39.778 -28.427 29.016  1   46.91  ? 345 ASP D N   1 
ATOM   8269 C  CA  . ASP D 2 175 ? -40.385 -29.344 28.024  1   51.69  ? 345 ASP D CA  1 
ATOM   8270 C  C   . ASP D 2 175 ? -41.747 -29.742 28.587  1   53.16  ? 345 ASP D C   1 
ATOM   8271 O  O   . ASP D 2 175 ? -41.785 -30.443 29.602  1   54.41  ? 345 ASP D O   1 
ATOM   8272 C  CB  . ASP D 2 175 ? -39.497 -30.538 27.729  1   52.21  ? 345 ASP D CB  1 
ATOM   8273 C  CG  . ASP D 2 175 ? -39.997 -31.487 26.652  1   55.39  ? 345 ASP D CG  1 
ATOM   8274 O  OD1 . ASP D 2 175 ? -40.562 -31.001 25.655  1   54.92  ? 345 ASP D OD1 1 
ATOM   8275 O  OD2 . ASP D 2 175 ? -39.803 -32.704 26.818  1   58.38  ? 345 ASP D OD2 1 
ATOM   8276 N  N   . PRO D 2 176 ? -42.857 -29.31  27.964  1   53.12  ? 346 PRO D N   1 
ATOM   8277 C  CA  . PRO D 2 176 ? -42.771 -28.678 26.655  1   51.87  ? 346 PRO D CA  1 
ATOM   8278 C  C   . PRO D 2 176 ? -43.162 -27.228 26.485  1   51.42  ? 346 PRO D C   1 
ATOM   8279 O  O   . PRO D 2 176 ? -43.267 -26.785 25.338  1   55.46  ? 346 PRO D O   1 
ATOM   8280 C  CB  . PRO D 2 176 ? -43.878 -29.575 26.135  1   49.84  ? 346 PRO D CB  1 
ATOM   8281 C  CG  . PRO D 2 176 ? -44.973 -29.42  27.156  1   49.39  ? 346 PRO D CG  1 
ATOM   8282 C  CD  . PRO D 2 176 ? -44.202 -29.521 28.448  1   51.19  ? 346 PRO D CD  1 
ATOM   8283 N  N   . TYR D 2 177 ? -43.301 -26.478 27.569  1   51.15  ? 347 TYR D N   1 
ATOM   8284 C  CA  . TYR D 2 177 ? -43.893 -25.119 27.468  1   47.84  ? 347 TYR D CA  1 
ATOM   8285 C  C   . TYR D 2 177 ? -42.952 -24.072 26.887  1   47.57  ? 347 TYR D C   1 
ATOM   8286 O  O   . TYR D 2 177 ? -43.442 -22.993 26.555  1   50.03  ? 347 TYR D O   1 
ATOM   8287 C  CB  . TYR D 2 177 ? -44.444 -24.913 28.879  1   44.26  ? 347 TYR D CB  1 
ATOM   8288 C  CG  . TYR D 2 177 ? -45.493 -25.96  29.212  1   45.8   ? 347 TYR D CG  1 
ATOM   8289 C  CD1 . TYR D 2 177 ? -46.625 -26.103 28.425  1   46.99  ? 347 TYR D CD1 1 
ATOM   8290 C  CD2 . TYR D 2 177 ? -45.335 -26.815 30.292  1   47.16  ? 347 TYR D CD2 1 
ATOM   8291 C  CE1 . TYR D 2 177 ? -47.582 -27.059 28.712  1   49.69  ? 347 TYR D CE1 1 
ATOM   8292 C  CE2 . TYR D 2 177 ? -46.286 -27.771 30.596  1   46.36  ? 347 TYR D CE2 1 
ATOM   8293 C  CZ  . TYR D 2 177 ? -47.407 -27.893 29.798  1   50.27  ? 347 TYR D CZ  1 
ATOM   8294 O  OH  . TYR D 2 177 ? -48.336 -28.838 30.085  1   52.24  ? 347 TYR D OH  1 
ATOM   8295 N  N   . LEU D 2 178 ? -41.668 -24.363 26.743  1   48.39  ? 348 LEU D N   1 
ATOM   8296 C  CA  . LEU D 2 178 ? -40.796 -23.367 26.075  1   50.87  ? 348 LEU D CA  1 
ATOM   8297 C  C   . LEU D 2 178 ? -41.172 -23.311 24.589  1   53.93  ? 348 LEU D C   1 
ATOM   8298 O  O   . LEU D 2 178 ? -40.769 -22.351 23.921  1   56.34  ? 348 LEU D O   1 
ATOM   8299 C  CB  . LEU D 2 178 ? -39.322 -23.71  26.265  1   49.52  ? 348 LEU D CB  1 
ATOM   8300 C  CG  . LEU D 2 178 ? -38.651 -23.18  27.533  1   49.85  ? 348 LEU D CG  1 
ATOM   8301 C  CD1 . LEU D 2 178 ? -37.168 -23.465 27.432  1   49.16  ? 348 LEU D CD1 1 
ATOM   8302 C  CD2 . LEU D 2 178 ? -38.902 -21.697 27.71   1   45.77  ? 348 LEU D CD2 1 
ATOM   8303 N  N   . LYS D 2 179 ? -41.928 -24.295 24.106  1   54.6   ? 349 LYS D N   1 
ATOM   8304 C  CA  . LYS D 2 179 ? -42.299 -24.37  22.673  1   58.62  ? 349 LYS D CA  1 
ATOM   8305 C  C   . LYS D 2 179 ? -43.515 -23.491 22.423  1   58.64  ? 349 LYS D C   1 
ATOM   8306 O  O   . LYS D 2 179 ? -43.793 -23.186 21.255  1   62.52  ? 349 LYS D O   1 
ATOM   8307 C  CB  . LYS D 2 179 ? -42.67  -25.809 22.315  1   60.98  ? 349 LYS D CB  1 
ATOM   8308 C  CG  . LYS D 2 179 ? -41.484 -26.735 22.121  1   66.96  ? 349 LYS D CG  1 
ATOM   8309 C  CD  . LYS D 2 179 ? -41.764 -28.157 22.588  1   67.05  ? 349 LYS D CD  1 
ATOM   8310 C  CE  . LYS D 2 179 ? -43.188 -28.543 22.377  1   70.38  ? 349 LYS D CE  1 
ATOM   8311 N  NZ  . LYS D 2 179 ? -43.287 -29.927 21.913  1   74.13  ? 349 LYS D NZ  1 
ATOM   8312 N  N   . TYR D 2 180 ? -44.204 -23.116 23.491  1   56.81  ? 350 TYR D N   1 
ATOM   8313 C  CA  . TYR D 2 180 ? -45.402 -22.301 23.346  1   54.57  ? 350 TYR D CA  1 
ATOM   8314 C  C   . TYR D 2 180 ? -45.157 -20.867 23.831  1   53.77  ? 350 TYR D C   1 
ATOM   8315 O  O   . TYR D 2 180 ? -44.422 -20.61  24.796  1   48.51  ? 350 TYR D O   1 
ATOM   8316 C  CB  . TYR D 2 180 ? -46.552 -22.96  24.114  1   54.3   ? 350 TYR D CB  1 
ATOM   8317 C  CG  . TYR D 2 180 ? -46.844 -24.421 23.785  1   56.29  ? 350 TYR D CG  1 
ATOM   8318 C  CD1 . TYR D 2 180 ? -47.405 -24.792 22.562  1   59.25  ? 350 TYR D CD1 1 
ATOM   8319 C  CD2 . TYR D 2 180 ? -46.578 -25.428 24.709  1   56.44  ? 350 TYR D CD2 1 
ATOM   8320 C  CE1 . TYR D 2 180 ? -47.675 -26.117 22.255  1   61.53  ? 350 TYR D CE1 1 
ATOM   8321 C  CE2 . TYR D 2 180 ? -46.858 -26.754 24.42   1   60.04  ? 350 TYR D CE2 1 
ATOM   8322 C  CZ  . TYR D 2 180 ? -47.409 -27.095 23.198  1   61.79  ? 350 TYR D CZ  1 
ATOM   8323 O  OH  . TYR D 2 180 ? -47.669 -28.402 22.942  1   66.09  ? 350 TYR D OH  1 
ATOM   8324 N  N   . LEU D 2 181 ? -45.825 -19.94  23.132  1   52.76  ? 351 LEU D N   1 
ATOM   8325 C  CA  . LEU D 2 181 ? -45.9   -18.533 23.482  1   49.31  ? 351 LEU D CA  1 
ATOM   8326 C  C   . LEU D 2 181 ? -46.803 -18.34  24.696  1   49.51  ? 351 LEU D C   1 
ATOM   8327 O  O   . LEU D 2 181 ? -47.784 -19.063 24.89   1   49.72  ? 351 LEU D O   1 
ATOM   8328 C  CB  . LEU D 2 181 ? -46.391 -17.721 22.286  1   49.7   ? 351 LEU D CB  1 
ATOM   8329 C  CG  . LEU D 2 181 ? -45.371 -17.486 21.166  1   49     ? 351 LEU D CG  1 
ATOM   8330 C  CD1 . LEU D 2 181 ? -46.007 -16.824 19.982  1   49.64  ? 351 LEU D CD1 1 
ATOM   8331 C  CD2 . LEU D 2 181 ? -44.212 -16.638 21.652  1   47.8   ? 351 LEU D CD2 1 
ATOM   8332 N  N   . PRO D 2 182 ? -46.479 -17.354 25.565  1   49.6   ? 352 PRO D N   1 
ATOM   8333 C  CA  . PRO D 2 182 ? -47.355 -17.026 26.695  1   49.94  ? 352 PRO D CA  1 
ATOM   8334 C  C   . PRO D 2 182 ? -48.836 -16.914 26.321  1   52.95  ? 352 PRO D C   1 
ATOM   8335 O  O   . PRO D 2 182 ? -49.69  -17.387 27.073  1   57.68  ? 352 PRO D O   1 
ATOM   8336 C  CB  . PRO D 2 182 ? -46.745 -15.695 27.187  1   47.35  ? 352 PRO D CB  1 
ATOM   8337 C  CG  . PRO D 2 182 ? -45.274 -15.834 26.854  1   43.25  ? 352 PRO D CG  1 
ATOM   8338 C  CD  . PRO D 2 182 ? -45.24  -16.545 25.518  1   44.43  ? 352 PRO D CD  1 
ATOM   8339 N  N   . SER D 2 183 ? -49.126 -16.316 25.152  1   51.48  ? 353 SER D N   1 
ATOM   8340 C  CA  . SER D 2 183 ? -50.494 -16.07  24.715  1   53.89  ? 353 SER D CA  1 
ATOM   8341 C  C   . SER D 2 183 ? -51.262 -17.382 24.537  1   59.06  ? 353 SER D C   1 
ATOM   8342 O  O   . SER D 2 183 ? -52.412 -17.492 24.958  1   62     ? 353 SER D O   1 
ATOM   8343 C  CB  . SER D 2 183 ? -50.55  -15.216 23.459  1   53.12  ? 353 SER D CB  1 
ATOM   8344 O  OG  . SER D 2 183 ? -50.032 -15.894 22.323  1   54.11  ? 353 SER D OG  1 
ATOM   8345 N  N   . VAL D 2 184 ? -50.609 -18.372 23.906  1   61.09  ? 354 VAL D N   1 
ATOM   8346 C  CA  . VAL D 2 184 ? -51.18  -19.679 23.621  1   58.11  ? 354 VAL D CA  1 
ATOM   8347 C  C   . VAL D 2 184 ? -51.375 -20.455 24.928  1   58.4   ? 354 VAL D C   1 
ATOM   8348 O  O   . VAL D 2 184 ? -52.416 -21.087 25.127  1   60.36  ? 354 VAL D O   1 
ATOM   8349 C  CB  . VAL D 2 184 ? -50.261 -20.431 22.636  1   57.93  ? 354 VAL D CB  1 
ATOM   8350 C  CG1 . VAL D 2 184 ? -50.597 -21.917 22.522  1   57.54  ? 354 VAL D CG1 1 
ATOM   8351 C  CG2 . VAL D 2 184 ? -50.22  -19.767 21.264  1   57.13  ? 354 VAL D CG2 1 
ATOM   8352 N  N   . ILE D 2 185 ? -50.373 -20.418 25.822  1   53.4   ? 355 ILE D N   1 
ATOM   8353 C  CA  . ILE D 2 185 ? -50.49  -21.203 27.04   1   53.42  ? 355 ILE D CA  1 
ATOM   8354 C  C   . ILE D 2 185 ? -51.659 -20.646 27.839  1   57.34  ? 355 ILE D C   1 
ATOM   8355 O  O   . ILE D 2 185 ? -52.437 -21.407 28.405  1   66.02  ? 355 ILE D O   1 
ATOM   8356 C  CB  . ILE D 2 185 ? -49.194 -21.23  27.881  1   51.01  ? 355 ILE D CB  1 
ATOM   8357 C  CG1 . ILE D 2 185 ? -48.007 -21.875 27.135  1   48.59  ? 355 ILE D CG1 1 
ATOM   8358 C  CG2 . ILE D 2 185 ? -49.443 -21.892 29.243  1   47.38  ? 355 ILE D CG2 1 
ATOM   8359 C  CD1 . ILE D 2 185 ? -46.652 -21.639 27.787  1   41.58  ? 355 ILE D CD1 1 
ATOM   8360 N  N   . ALA D 2 186 ? -51.775 -19.317 27.88   1   55.45  ? 356 ALA D N   1 
ATOM   8361 C  CA  . ALA D 2 186 ? -52.874 -18.679 28.585  1   56.21  ? 356 ALA D CA  1 
ATOM   8362 C  C   . ALA D 2 186 ? -54.225 -19.091 27.987  1   59.93  ? 356 ALA D C   1 
ATOM   8363 O  O   . ALA D 2 186 ? -55.183 -19.332 28.72   1   62.87  ? 356 ALA D O   1 
ATOM   8364 C  CB  . ALA D 2 186 ? -52.68  -17.182 28.55   1   57.47  ? 356 ALA D CB  1 
ATOM   8365 N  N   . ALA D 2 187 ? -54.305 -19.161 26.653  1   58.85  ? 357 ALA D N   1 
ATOM   8366 C  CA  . ALA D 2 187 ? -55.534 -19.568 25.994  1   61.13  ? 357 ALA D CA  1 
ATOM   8367 C  C   . ALA D 2 187 ? -55.878 -20.986 26.432  1   61.93  ? 357 ALA D C   1 
ATOM   8368 O  O   . ALA D 2 187 ? -56.981 -21.231 26.916  1   62.97  ? 357 ALA D O   1 
ATOM   8369 C  CB  . ALA D 2 187 ? -55.379 -19.466 24.497  1   62.07  ? 357 ALA D CB  1 
ATOM   8370 N  N   . ALA D 2 188 ? -54.896 -21.888 26.295  1   60.2   ? 358 ALA D N   1 
ATOM   8371 C  CA  . ALA D 2 188 ? -55.054 -23.263 26.727  1   61.83  ? 358 ALA D CA  1 
ATOM   8372 C  C   . ALA D 2 188 ? -55.471 -23.312 28.191  1   62.68  ? 358 ALA D C   1 
ATOM   8373 O  O   . ALA D 2 188 ? -56.368 -24.071 28.558  1   67.49  ? 358 ALA D O   1 
ATOM   8374 C  CB  . ALA D 2 188 ? -53.788 -24.054 26.497  1   59.71  ? 358 ALA D CB  1 
ATOM   8375 N  N   . ALA D 2 189 ? -54.812 -22.511 29.028  1   60.45  ? 359 ALA D N   1 
ATOM   8376 C  CA  . ALA D 2 189 ? -55.068 -22.602 30.453  1   62.13  ? 359 ALA D CA  1 
ATOM   8377 C  C   . ALA D 2 189 ? -56.458 -22.066 30.779  1   67.4   ? 359 ALA D C   1 
ATOM   8378 O  O   . ALA D 2 189 ? -57.073 -22.536 31.739  1   71.64  ? 359 ALA D O   1 
ATOM   8379 C  CB  . ALA D 2 189 ? -54.003 -21.9   31.247  1   59.73  ? 359 ALA D CB  1 
ATOM   8380 N  N   . PHE D 2 190 ? -56.947 -21.103 29.973  1   67.05  ? 360 PHE D N   1 
ATOM   8381 C  CA  . PHE D 2 190 ? -58.278 -20.535 30.164  1   67.1   ? 360 PHE D CA  1 
ATOM   8382 C  C   . PHE D 2 190 ? -59.362 -21.52  29.708  1   69.9   ? 360 PHE D C   1 
ATOM   8383 O  O   . PHE D 2 190 ? -60.328 -21.775 30.433  1   68.51  ? 360 PHE D O   1 
ATOM   8384 C  CB  . PHE D 2 190 ? -58.479 -19.213 29.424  1   65.47  ? 360 PHE D CB  1 
ATOM   8385 C  CG  . PHE D 2 190 ? -59.738 -18.473 29.85   1   65.78  ? 360 PHE D CG  1 
ATOM   8386 C  CD1 . PHE D 2 190 ? -60.009 -18.228 31.198  1   64.12  ? 360 PHE D CD1 1 
ATOM   8387 C  CD2 . PHE D 2 190 ? -60.664 -18.055 28.896  1   67.82  ? 360 PHE D CD2 1 
ATOM   8388 C  CE1 . PHE D 2 190 ? -61.162 -17.55  31.573  1   66.26  ? 360 PHE D CE1 1 
ATOM   8389 C  CE2 . PHE D 2 190 ? -61.811 -17.38  29.278  1   67.28  ? 360 PHE D CE2 1 
ATOM   8390 C  CZ  . PHE D 2 190 ? -62.065 -17.131 30.611  1   67.38  ? 360 PHE D CZ  1 
ATOM   8391 N  N   . HIS D 2 191 ? -59.192 -22.087 28.505  1   70.07  ? 361 HIS D N   1 
ATOM   8392 C  CA  . HIS D 2 191 ? -60.092 -23.15  28.093  1   72.5   ? 361 HIS D CA  1 
ATOM   8393 C  C   . HIS D 2 191 ? -60.198 -24.215 29.183  1   71.56  ? 361 HIS D C   1 
ATOM   8394 O  O   . HIS D 2 191 ? -61.273 -24.427 29.731  1   77.94  ? 361 HIS D O   1 
ATOM   8395 C  CB  . HIS D 2 191 ? -59.7   -23.811 26.772  1   72.05  ? 361 HIS D CB  1 
ATOM   8396 C  CG  . HIS D 2 191 ? -60.593 -24.986 26.594  1   76.84  ? 361 HIS D CG  1 
ATOM   8397 N  ND1 . HIS D 2 191 ? -61.849 -24.895 26.033  1   79.95  ? 361 HIS D ND1 1 
ATOM   8398 C  CD2 . HIS D 2 191 ? -60.456 -26.253 26.985  1   76.98  ? 361 HIS D CD2 1 
ATOM   8399 C  CE1 . HIS D 2 191 ? -62.423 -26.087 26.049  1   82.15  ? 361 HIS D CE1 1 
ATOM   8400 N  NE2 . HIS D 2 191 ? -61.6   -26.922 26.631  1   80.51  ? 361 HIS D NE2 1 
ATOM   8401 N  N   . LEU D 2 192 ? -59.09  -24.895 29.475  1   66.79  ? 362 LEU D N   1 
ATOM   8402 C  CA  . LEU D 2 192 ? -59.112 -26.015 30.397  1   68.66  ? 362 LEU D CA  1 
ATOM   8403 C  C   . LEU D 2 192 ? -59.844 -25.65  31.693  1   71.98  ? 362 LEU D C   1 
ATOM   8404 O  O   . LEU D 2 192 ? -60.724 -26.399 32.132  1   78.89  ? 362 LEU D O   1 
ATOM   8405 C  CB  . LEU D 2 192 ? -57.704 -26.576 30.618  1   66.41  ? 362 LEU D CB  1 
ATOM   8406 C  CG  . LEU D 2 192 ? -57.589 -27.91  31.373  1   68.24  ? 362 LEU D CG  1 
ATOM   8407 C  CD1 . LEU D 2 192 ? -58.47  -29.033 30.824  1   72.88  ? 362 LEU D CD1 1 
ATOM   8408 C  CD2 . LEU D 2 192 ? -56.155 -28.394 31.464  1   63.84  ? 362 LEU D CD2 1 
ATOM   8409 N  N   . ALA D 2 193 ? -59.512 -24.489 32.28   1   71.77  ? 363 ALA D N   1 
ATOM   8410 C  CA  . ALA D 2 193 ? -60.112 -24.024 33.525  1   73.35  ? 363 ALA D CA  1 
ATOM   8411 C  C   . ALA D 2 193 ? -61.648 -23.968 33.443  1   79.78  ? 363 ALA D C   1 
ATOM   8412 O  O   . ALA D 2 193 ? -62.33  -24.613 34.246  1   84.11  ? 363 ALA D O   1 
ATOM   8413 C  CB  . ALA D 2 193 ? -59.503 -22.704 33.935  1   66.84  ? 363 ALA D CB  1 
ATOM   8414 N  N   . LEU D 2 194 ? -62.171 -23.279 32.426  1   78.88  ? 364 LEU D N   1 
ATOM   8415 C  CA  . LEU D 2 194 ? -63.638 -23.18  32.221  1   79.74  ? 364 LEU D CA  1 
ATOM   8416 C  C   . LEU D 2 194 ? -64.274 -24.575 32.256  1   83.3   ? 364 LEU D C   1 
ATOM   8417 O  O   . LEU D 2 194 ? -65.159 -24.797 33.097  1   82.79  ? 364 LEU D O   1 
ATOM   8418 C  CB  . LEU D 2 194 ? -63.855 -22.524 30.863  1   80.7   ? 364 LEU D CB  1 
ATOM   8419 C  CG  . LEU D 2 194 ? -63.705 -21.003 30.8    1   83.83  ? 364 LEU D CG  1 
ATOM   8420 C  CD1 . LEU D 2 194 ? -63.603 -20.595 29.344  1   83.44  ? 364 LEU D CD1 1 
ATOM   8421 C  CD2 . LEU D 2 194 ? -64.903 -20.347 31.454  1   89.17  ? 364 LEU D CD2 1 
ATOM   8422 N  N   . TYR D 2 195 ? -63.852 -25.453 31.343  1   82.33  ? 365 TYR D N   1 
ATOM   8423 C  CA  . TYR D 2 195 ? -64.396 -26.834 31.255  1   84.61  ? 365 TYR D CA  1 
ATOM   8424 C  C   . TYR D 2 195 ? -64.498 -27.459 32.635  1   83.56  ? 365 TYR D C   1 
ATOM   8425 O  O   . TYR D 2 195 ? -65.596 -27.911 33.024  1   84.38  ? 365 TYR D O   1 
ATOM   8426 C  CB  . TYR D 2 195 ? -63.36  -27.533 30.372  1   84.46  ? 365 TYR D CB  1 
ATOM   8427 C  CG  . TYR D 2 195 ? -63.758 -28.84  29.701  1   88.84  ? 365 TYR D CG  1 
ATOM   8428 C  CD1 . TYR D 2 195 ? -64.023 -29.983 30.445  1   92.64  ? 365 TYR D CD1 1 
ATOM   8429 C  CD2 . TYR D 2 195 ? -63.831 -28.938 28.317  1   89     ? 365 TYR D CD2 1 
ATOM   8430 C  CE1 . TYR D 2 195 ? -64.372 -31.176 29.833  1   95.48  ? 365 TYR D CE1 1 
ATOM   8431 C  CE2 . TYR D 2 195 ? -64.176 -30.125 27.693  1   94.3   ? 365 TYR D CE2 1 
ATOM   8432 C  CZ  . TYR D 2 195 ? -64.448 -31.247 28.454  1   97.73  ? 365 TYR D CZ  1 
ATOM   8433 O  OH  . TYR D 2 195 ? -64.791 -32.42  27.845  1   101.87 ? 365 TYR D OH  1 
ATOM   8434 N  N   . THR D 2 196 ? -63.386 -27.494 33.368  1   80.32  ? 366 THR D N   1 
ATOM   8435 C  CA  . THR D 2 196 ? -63.356 -28.166 34.683  1   79.59  ? 366 THR D CA  1 
ATOM   8436 C  C   . THR D 2 196 ? -64.38  -27.576 35.627  1   83.36  ? 366 THR D C   1 
ATOM   8437 O  O   . THR D 2 196 ? -65.016 -28.357 36.358  1   84.93  ? 366 THR D O   1 
ATOM   8438 C  CB  . THR D 2 196 ? -61.942 -28.074 35.254  1   74.54  ? 366 THR D CB  1 
ATOM   8439 O  OG1 . THR D 2 196 ? -61.066 -28.329 34.16   1   71.85  ? 366 THR D OG1 1 
ATOM   8440 C  CG2 . THR D 2 196 ? -61.697 -29.068 36.374  1   72.21  ? 366 THR D CG2 1 
ATOM   8441 N  N   . VAL D 2 197 ? -64.553 -26.257 35.63   1   84     ? 367 VAL D N   1 
ATOM   8442 C  CA  . VAL D 2 197 ? -65.45  -25.63  36.645  1   88.49  ? 367 VAL D CA  1 
ATOM   8443 C  C   . VAL D 2 197 ? -66.879 -25.495 36.106  1   93.42  ? 367 VAL D C   1 
ATOM   8444 O  O   . VAL D 2 197 ? -67.814 -25.842 36.845  1   96.19  ? 367 VAL D O   1 
ATOM   8445 C  CB  . VAL D 2 197 ? -64.882 -24.264 37.065  1   87.17  ? 367 VAL D CB  1 
ATOM   8446 C  CG1 . VAL D 2 197 ? -65.763 -23.573 38.097  1   88.78  ? 367 VAL D CG1 1 
ATOM   8447 C  CG2 . VAL D 2 197 ? -63.452 -24.385 37.577  1   81.96  ? 367 VAL D CG2 1 
ATOM   8448 N  N   . THR D 2 198 ? -67.032 -25.033 34.867  1   95.06  ? 368 THR D N   1 
ATOM   8449 C  CA  . THR D 2 198 ? -68.378 -24.778 34.323  1   97.65  ? 368 THR D CA  1 
ATOM   8450 C  C   . THR D 2 198 ? -68.671 -25.7   33.168  1   96.59  ? 368 THR D C   1 
ATOM   8451 O  O   . THR D 2 198 ? -69.821 -26.148 33.061  1   101.27 ? 368 THR D O   1 
ATOM   8452 C  CB  . THR D 2 198 ? -68.401 -23.327 33.858  1   97.76  ? 368 THR D CB  1 
ATOM   8453 O  OG1 . THR D 2 198 ? -67.422 -23.285 32.825  1   93.65  ? 368 THR D OG1 1 
ATOM   8454 C  CG2 . THR D 2 198 ? -68.048 -22.352 34.964  1   94.96  ? 368 THR D CG2 1 
ATOM   8455 N  N   . GLY D 2 199 ? -67.682 -25.966 32.32   1   94.21  ? 369 GLY D N   1 
ATOM   8456 C  CA  . GLY D 2 199 ? -67.929 -26.754 31.105  1   96.81  ? 369 GLY D CA  1 
ATOM   8457 C  C   . GLY D 2 199 ? -68.412 -25.817 30.031  1   97.99  ? 369 GLY D C   1 
ATOM   8458 O  O   . GLY D 2 199 ? -69.389 -26.165 29.35   1   96.92  ? 369 GLY D O   1 
ATOM   8459 N  N   . GLN D 2 200 ? -67.747 -24.672 29.869  1   99.7   ? 370 GLN D N   1 
ATOM   8460 C  CA  . GLN D 2 200 ? -68.26  -23.648 28.924  1   106.64 ? 370 GLN D CA  1 
ATOM   8461 C  C   . GLN D 2 200 ? -67.408 -23.566 27.651  1   107.08 ? 370 GLN D C   1 
ATOM   8462 O  O   . GLN D 2 200 ? -67.98  -23.142 26.627  1   119.87 ? 370 GLN D O   1 
ATOM   8463 C  CB  . GLN D 2 200 ? -68.337 -22.306 29.649  1   107.37 ? 370 GLN D CB  1 
ATOM   8464 C  CG  . GLN D 2 200 ? -69.573 -22.154 30.527  1   114.35 ? 370 GLN D CG  1 
ATOM   8465 C  CD  . GLN D 2 200 ? -69.818 -20.729 30.968  1   115.15 ? 370 GLN D CD  1 
ATOM   8466 O  OE1 . GLN D 2 200 ? -69.531 -19.772 30.24   1   112.51 ? 370 GLN D OE1 1 
ATOM   8467 N  NE2 . GLN D 2 200 ? -70.355 -20.573 32.169  1   117.79 ? 370 GLN D NE2 1 
ATOM   8468 N  N   . SER D 2 201 ? -66.115 -23.887 27.722  1   99.37  ? 371 SER D N   1 
ATOM   8469 C  CA  . SER D 2 201 ? -65.214 -23.911 26.533  1   96.74  ? 371 SER D CA  1 
ATOM   8470 C  C   . SER D 2 201 ? -64.748 -22.519 26.075  1   93.87  ? 371 SER D C   1 
ATOM   8471 O  O   . SER D 2 201 ? -65.491 -21.544 26.282  1   95.98  ? 371 SER D O   1 
ATOM   8472 C  CB  . SER D 2 201 ? -65.797 -24.701 25.377  1   98.44  ? 371 SER D CB  1 
ATOM   8473 O  OG  . SER D 2 201 ? -65.339 -24.197 24.131  1   99     ? 371 SER D OG  1 
ATOM   8474 N  N   . TRP D 2 202 ? -63.556 -22.447 25.469  1   88.07  ? 372 TRP D N   1 
ATOM   8475 C  CA  . TRP D 2 202 ? -62.989 -21.183 24.938  1   82.57  ? 372 TRP D CA  1 
ATOM   8476 C  C   . TRP D 2 202 ? -64.088 -20.341 24.313  1   86.09  ? 372 TRP D C   1 
ATOM   8477 O  O   . TRP D 2 202 ? -64.681 -20.767 23.311  1   88.79  ? 372 TRP D O   1 
ATOM   8478 C  CB  . TRP D 2 202 ? -61.915 -21.543 23.905  1   79.52  ? 372 TRP D CB  1 
ATOM   8479 C  CG  . TRP D 2 202 ? -61.112 -20.415 23.313  1   76.46  ? 372 TRP D CG  1 
ATOM   8480 C  CD1 . TRP D 2 202 ? -61.051 -20.083 21.993  1   78.71  ? 372 TRP D CD1 1 
ATOM   8481 C  CD2 . TRP D 2 202 ? -60.206 -19.519 23.992  1   71.89  ? 372 TRP D CD2 1 
ATOM   8482 N  NE1 . TRP D 2 202 ? -60.198 -19.03  21.803  1   78.1   ? 372 TRP D NE1 1 
ATOM   8483 C  CE2 . TRP D 2 202 ? -59.662 -18.666 23.008  1   70.83  ? 372 TRP D CE2 1 
ATOM   8484 C  CE3 . TRP D 2 202 ? -59.81  -19.35  25.323  1   68.51  ? 372 TRP D CE3 1 
ATOM   8485 C  CZ2 . TRP D 2 202 ? -58.748 -17.663 23.316  1   66.9   ? 372 TRP D CZ2 1 
ATOM   8486 C  CZ3 . TRP D 2 202 ? -58.903 -18.36  25.622  1   66.8   ? 372 TRP D CZ3 1 
ATOM   8487 C  CH2 . TRP D 2 202 ? -58.382 -17.529 24.633  1   64.84  ? 372 TRP D CH2 1 
ATOM   8488 N  N   . PRO D 2 203 ? -64.372 -19.145 24.861  1   88.4   ? 373 PRO D N   1 
ATOM   8489 C  CA  . PRO D 2 203 ? -65.425 -18.292 24.329  1   90.95  ? 373 PRO D CA  1 
ATOM   8490 C  C   . PRO D 2 203 ? -65.118 -17.794 22.93   1   89.32  ? 373 PRO D C   1 
ATOM   8491 O  O   . PRO D 2 203 ? -63.941 -17.607 22.584  1   83.84  ? 373 PRO D O   1 
ATOM   8492 C  CB  . PRO D 2 203 ? -65.489 -17.151 25.345  1   90.83  ? 373 PRO D CB  1 
ATOM   8493 C  CG  . PRO D 2 203 ? -64.796 -17.699 26.571  1   87.27  ? 373 PRO D CG  1 
ATOM   8494 C  CD  . PRO D 2 203 ? -63.7   -18.582 26.012  1   85.05  ? 373 PRO D CD  1 
ATOM   8495 N  N   . GLU D 2 204 ? -66.249 -17.587 22.164  1   92.3   ? 374 GLU D N   1 
ATOM   8496 C  CA  . GLU D 2 204 ? -66.126 -17.087 20.772  1   91.99  ? 374 GLU D CA  1 
ATOM   8497 C  C   . GLU D 2 204 ? -65.576 -15.661 20.818  1   89.62  ? 374 GLU D C   1 
ATOM   8498 O  O   . GLU D 2 204 ? -64.675 -15.349 20.017  1   86.09  ? 374 GLU D O   1 
ATOM   8499 C  CB  . GLU D 2 204 ? -67.492 -17.179 20.097  1   94.04  ? 374 GLU D CB  1 
ATOM   8500 C  CG  . GLU D 2 204 ? -67.534 -16.519 18.722  1   97.63  ? 374 GLU D CG  1 
ATOM   8501 C  CD  . GLU D 2 204 ? -66.615 -17.148 17.692  1   96.58  ? 374 GLU D CD  1 
ATOM   8502 O  OE1 . GLU D 2 204 ? -66.384 -18.369 17.768  1   96.65  ? 374 GLU D OE1 1 
ATOM   8503 O  OE2 . GLU D 2 204 ? -66.133 -16.413 16.809  1   97.38  ? 374 GLU D OE2 1 
ATOM   8504 N  N   . SER D 2 205 ? -66.059 -14.852 21.711  1   89.44  ? 375 SER D N   1 
ATOM   8505 C  CA  . SER D 2 205 ? -65.535 -13.5   21.869  1   87.91  ? 375 SER D CA  1 
ATOM   8506 C  C   . SER D 2 205 ? -64.004 -13.499 21.939  1   81.99  ? 375 SER D C   1 
ATOM   8507 O  O   . SER D 2 205 ? -63.367 -12.579 21.435  1   80.23  ? 375 SER D O   1 
ATOM   8508 C  CB  . SER D 2 205 ? -66.171 -12.769 23.052  1   87.35  ? 375 SER D CB  1 
ATOM   8509 O  OG  . SER D 2 205 ? -65.923 -13.426 24.29   1   85.59  ? 375 SER D OG  1 
ATOM   8510 N  N   . LEU D 2 206 ? -63.422 -14.538 22.543  1   79.31  ? 376 LEU D N   1 
ATOM   8511 C  CA  . LEU D 2 206 ? -61.942 -14.621 22.692  1   76.46  ? 376 LEU D CA  1 
ATOM   8512 C  C   . LEU D 2 206 ? -61.297 -15.194 21.424  1   75.25  ? 376 LEU D C   1 
ATOM   8513 O  O   . LEU D 2 206 ? -60.094 -14.969 21.231  1   70.15  ? 376 LEU D O   1 
ATOM   8514 C  CB  . LEU D 2 206 ? -61.606 -15.45  23.924  1   73.79  ? 376 LEU D CB  1 
ATOM   8515 C  CG  . LEU D 2 206 ? -61.504 -14.657 25.227  1   73.69  ? 376 LEU D CG  1 
ATOM   8516 C  CD1 . LEU D 2 206 ? -61.167 -15.588 26.363  1   73.37  ? 376 LEU D CD1 1 
ATOM   8517 C  CD2 . LEU D 2 206 ? -60.454 -13.577 25.08   1   70.29  ? 376 LEU D CD2 1 
ATOM   8518 N  N   . VAL D 2 207 ? -62.063 -15.905 20.6    1   79.88  ? 377 VAL D N   1 
ATOM   8519 C  CA  . VAL D 2 207 ? -61.52  -16.377 19.295  1   81.35  ? 377 VAL D CA  1 
ATOM   8520 C  C   . VAL D 2 207 ? -61.311 -15.13  18.438  1   83.12  ? 377 VAL D C   1 
ATOM   8521 O  O   . VAL D 2 207 ? -60.286 -15.047 17.744  1   81.03  ? 377 VAL D O   1 
ATOM   8522 C  CB  . VAL D 2 207 ? -62.48  -17.354 18.6    1   82.97  ? 377 VAL D CB  1 
ATOM   8523 C  CG1 . VAL D 2 207 ? -61.921 -17.857 17.276  1   83.87  ? 377 VAL D CG1 1 
ATOM   8524 C  CG2 . VAL D 2 207 ? -62.868 -18.518 19.501  1   85.47  ? 377 VAL D CG2 1 
ATOM   8525 N  N   . GLN D 2 208 ? -62.161 -14.187 18.532  1   86.58  ? 378 GLN D N   1 
ATOM   8526 C  CA  . GLN D 2 208 ? -62.139 -12.962 17.755  1   91.27  ? 378 GLN D CA  1 
ATOM   8527 C  C   . GLN D 2 208 ? -60.922 -12.123 18.123  1   84.92  ? 378 GLN D C   1 
ATOM   8528 O  O   . GLN D 2 208 ? -60.289 -11.557 17.235  1   82.29  ? 378 GLN D O   1 
ATOM   8529 C  CB  . GLN D 2 208 ? -63.429 -12.171 17.959  1   103.26 ? 378 GLN D CB  1 
ATOM   8530 C  CG  . GLN D 2 208 ? -64.628 -12.774 17.237  1   112.94 ? 378 GLN D CG  1 
ATOM   8531 C  CD  . GLN D 2 208 ? -64.436 -12.841 15.737  1   124.05 ? 378 GLN D CD  1 
ATOM   8532 O  OE1 . GLN D 2 208 ? -64.416 -13.926 15.141  1   129.46 ? 378 GLN D OE1 1 
ATOM   8533 N  NE2 . GLN D 2 208 ? -64.294 -11.678 15.111  1   127.64 ? 378 GLN D NE2 1 
ATOM   8534 N  N   . LYS D 2 209 ? -60.611 -12.068 19.428  1   82.44  ? 379 LYS D N   1 
ATOM   8535 C  CA  . LYS D 2 209 ? -59.509 -11.272 19.955  1   80.26  ? 379 LYS D CA  1 
ATOM   8536 C  C   . LYS D 2 209 ? -58.184 -11.816 19.422  1   78.29  ? 379 LYS D C   1 
ATOM   8537 O  O   . LYS D 2 209 ? -57.41  -11.084 18.806  1   77.74  ? 379 LYS D O   1 
ATOM   8538 C  CB  . LYS D 2 209 ? -59.513 -11.222 21.493  1   77.67  ? 379 LYS D CB  1 
ATOM   8539 C  CG  . LYS D 2 209 ? -58.855 -9.992  22.135  1   78.74  ? 379 LYS D CG  1 
ATOM   8540 C  CD  . LYS D 2 209 ? -58.608 -10.051 23.644  1   82     ? 379 LYS D CD  1 
ATOM   8541 C  CE  . LYS D 2 209 ? -59.007 -8.814  24.416  1   81.57  ? 379 LYS D CE  1 
ATOM   8542 N  NZ  . LYS D 2 209 ? -58.401 -7.569  23.931  1   79.54  ? 379 LYS D NZ  1 
ATOM   8543 N  N   . THR D 2 210 ? -57.973 -13.124 19.638  1   75.7   ? 380 THR D N   1 
ATOM   8544 C  CA  . THR D 2 210 ? -56.678 -13.784 19.556  1   72.57  ? 380 THR D CA  1 
ATOM   8545 C  C   . THR D 2 210 ? -56.468 -14.462 18.2    1   73.17  ? 380 THR D C   1 
ATOM   8546 O  O   . THR D 2 210 ? -55.339 -14.737 17.809  1   68.38  ? 380 THR D O   1 
ATOM   8547 C  CB  . THR D 2 210 ? -56.575 -14.79  20.707  1   73.46  ? 380 THR D CB  1 
ATOM   8548 O  OG1 . THR D 2 210 ? -57.429 -15.897 20.429  1   82.2   ? 380 THR D OG1 1 
ATOM   8549 C  CG2 . THR D 2 210 ? -56.998 -14.206 22.045  1   69.61  ? 380 THR D CG2 1 
ATOM   8550 N  N   . GLY D 2 211 ? -57.558 -14.781 17.494  1   79.05  ? 381 GLY D N   1 
ATOM   8551 C  CA  . GLY D 2 211 ? -57.468 -15.557 16.267  1   80.68  ? 381 GLY D CA  1 
ATOM   8552 C  C   . GLY D 2 211 ? -57.015 -16.988 16.561  1   80.97  ? 381 GLY D C   1 
ATOM   8553 O  O   . GLY D 2 211 ? -56.494 -17.674 15.68   1   81.68  ? 381 GLY D O   1 
ATOM   8554 N  N   . TYR D 2 212 ? -57.209 -17.413 17.819  1   78.83  ? 382 TYR D N   1 
ATOM   8555 C  CA  . TYR D 2 212 ? -56.881 -18.757 18.269  1   75.61  ? 382 TYR D CA  1 
ATOM   8556 C  C   . TYR D 2 212 ? -58.171 -19.56  18.354  1   76.14  ? 382 TYR D C   1 
ATOM   8557 O  O   . TYR D 2 212 ? -59.114 -19.15  19.027  1   73     ? 382 TYR D O   1 
ATOM   8558 C  CB  . TYR D 2 212 ? -56.196 -18.795 19.642  1   69.48  ? 382 TYR D CB  1 
ATOM   8559 C  CG  . TYR D 2 212 ? -54.778 -18.243 19.713  1   64.93  ? 382 TYR D CG  1 
ATOM   8560 C  CD1 . TYR D 2 212 ? -53.918 -18.318 18.62   1   65.55  ? 382 TYR D CD1 1 
ATOM   8561 C  CD2 . TYR D 2 212 ? -54.297 -17.656 20.879  1   61.49  ? 382 TYR D CD2 1 
ATOM   8562 C  CE1 . TYR D 2 212 ? -52.627 -17.816 18.678  1   63.91  ? 382 TYR D CE1 1 
ATOM   8563 C  CE2 . TYR D 2 212 ? -53.006 -17.147 20.953  1   60.75  ? 382 TYR D CE2 1 
ATOM   8564 C  CZ  . TYR D 2 212 ? -52.168 -17.223 19.847  1   61.05  ? 382 TYR D CZ  1 
ATOM   8565 O  OH  . TYR D 2 212 ? -50.89  -16.741 19.909  1   55.88  ? 382 TYR D OH  1 
ATOM   8566 N  N   . THR D 2 213 ? -58.178 -20.706 17.668  1   79.95  ? 383 THR D N   1 
ATOM   8567 C  CA  . THR D 2 213 ? -59.272 -21.659 17.78   1   86.23  ? 383 THR D CA  1 
ATOM   8568 C  C   . THR D 2 213 ? -58.802 -22.867 18.591  1   85.78  ? 383 THR D C   1 
ATOM   8569 O  O   . THR D 2 213 ? -57.602 -23.105 18.721  1   85.82  ? 383 THR D O   1 
ATOM   8570 C  CB  . THR D 2 213 ? -59.797 -22.04  16.391  1   90.51  ? 383 THR D CB  1 
ATOM   8571 O  OG1 . THR D 2 213 ? -58.828 -22.895 15.792  1   93.73  ? 383 THR D OG1 1 
ATOM   8572 C  CG2 . THR D 2 213 ? -60.084 -20.833 15.511  1   88.51  ? 383 THR D CG2 1 
ATOM   8573 N  N   . LEU D 2 214 ? -59.756 -23.626 19.142  1   87.69  ? 384 LEU D N   1 
ATOM   8574 C  CA  . LEU D 2 214 ? -59.43  -24.879 19.805  1   86.41  ? 384 LEU D CA  1 
ATOM   8575 C  C   . LEU D 2 214 ? -58.63  -25.771 18.852  1   89.53  ? 384 LEU D C   1 
ATOM   8576 O  O   . LEU D 2 214 ? -57.801 -26.555 19.306  1   90.21  ? 384 LEU D O   1 
ATOM   8577 C  CB  . LEU D 2 214 ? -60.658 -25.581 20.393  1   84.69  ? 384 LEU D CB  1 
ATOM   8578 C  CG  . LEU D 2 214 ? -61.261 -24.956 21.659  1   81.2   ? 384 LEU D CG  1 
ATOM   8579 C  CD1 . LEU D 2 214 ? -62.719 -25.368 21.865  1   82.89  ? 384 LEU D CD1 1 
ATOM   8580 C  CD2 . LEU D 2 214 ? -60.446 -25.298 22.89   1   74.34  ? 384 LEU D CD2 1 
ATOM   8581 N  N   . GLU D 2 215 ? -58.853 -25.631 17.535  1   91.96  ? 385 GLU D N   1 
ATOM   8582 C  CA  . GLU D 2 215 ? -58.001 -26.288 16.554  1   93.39  ? 385 GLU D CA  1 
ATOM   8583 C  C   . GLU D 2 215 ? -56.551 -25.875 16.805  1   90.72  ? 385 GLU D C   1 
ATOM   8584 O  O   . GLU D 2 215 ? -55.705 -26.714 17.1    1   91.43  ? 385 GLU D O   1 
ATOM   8585 C  CB  . GLU D 2 215 ? -58.424 -26.047 15.103  1   98.97  ? 385 GLU D CB  1 
ATOM   8586 C  CG  . GLU D 2 215 ? -57.551 -26.793 14.096  1   104.86 ? 385 GLU D CG  1 
ATOM   8587 C  CD  . GLU D 2 215 ? -58.166 -27.021 12.722  1   112.02 ? 385 GLU D CD  1 
ATOM   8588 O  OE1 . GLU D 2 215 ? -59.223 -27.682 12.631  1   116.14 ? 385 GLU D OE1 1 
ATOM   8589 O  OE2 . GLU D 2 215 ? -57.582 -26.542 11.732  1   114.36 ? 385 GLU D OE2 1 
ATOM   8590 N  N   . THR D 2 216 ? -56.272 -24.571 16.733  1   86.28  ? 386 THR D N   1 
ATOM   8591 C  CA  . THR D 2 216 ? -54.891 -24.118 16.808  1   81.93  ? 386 THR D CA  1 
ATOM   8592 C  C   . THR D 2 216 ? -54.319 -24.381 18.204  1   78.23  ? 386 THR D C   1 
ATOM   8593 O  O   . THR D 2 216 ? -53.111 -24.544 18.341  1   76.17  ? 386 THR D O   1 
ATOM   8594 C  CB  . THR D 2 216 ? -54.728 -22.662 16.366  1   80.85  ? 386 THR D CB  1 
ATOM   8595 O  OG1 . THR D 2 216 ? -55.2   -21.866 17.447  1   78.67  ? 386 THR D OG1 1 
ATOM   8596 C  CG2 . THR D 2 216 ? -55.446 -22.328 15.068  1   84.34  ? 386 THR D CG2 1 
ATOM   8597 N  N   . LEU D 2 217 ? -55.192 -24.471 19.218  1   76.59  ? 387 LEU D N   1 
ATOM   8598 C  CA  . LEU D 2 217 ? -54.799 -24.665 20.608  1   72.19  ? 387 LEU D CA  1 
ATOM   8599 C  C   . LEU D 2 217 ? -54.732 -26.142 21.028  1   75.42  ? 387 LEU D C   1 
ATOM   8600 O  O   . LEU D 2 217 ? -54.63  -26.415 22.229  1   71.38  ? 387 LEU D O   1 
ATOM   8601 C  CB  . LEU D 2 217 ? -55.808 -23.923 21.485  1   70.69  ? 387 LEU D CB  1 
ATOM   8602 C  CG  . LEU D 2 217 ? -55.805 -22.394 21.424  1   70.96  ? 387 LEU D CG  1 
ATOM   8603 C  CD1 . LEU D 2 217 ? -56.875 -21.92  22.384  1   70.58  ? 387 LEU D CD1 1 
ATOM   8604 C  CD2 . LEU D 2 217 ? -54.446 -21.787 21.786  1   68.18  ? 387 LEU D CD2 1 
ATOM   8605 N  N   . LYS D 2 218 ? -54.803 -27.094 20.076  1   75.75  ? 388 LYS D N   1 
ATOM   8606 C  CA  . LYS D 2 218 ? -54.853 -28.505 20.434  1   77.02  ? 388 LYS D CA  1 
ATOM   8607 C  C   . LYS D 2 218 ? -53.528 -28.948 21.072  1   78.29  ? 388 LYS D C   1 
ATOM   8608 O  O   . LYS D 2 218 ? -53.528 -29.452 22.205  1   76.98  ? 388 LYS D O   1 
ATOM   8609 C  CB  . LYS D 2 218 ? -55.288 -29.4   19.265  1   82.45  ? 388 LYS D CB  1 
ATOM   8610 C  CG  . LYS D 2 218 ? -55.812 -30.804 19.587  1   82.69  ? 388 LYS D CG  1 
ATOM   8611 C  CD  . LYS D 2 218 ? -56.105 -31.627 18.332  1   86.23  ? 388 LYS D CD  1 
ATOM   8612 C  CE  . LYS D 2 218 ? -57.001 -32.822 18.541  1   87.32  ? 388 LYS D CE  1 
ATOM   8613 N  NZ  . LYS D 2 218 ? -56.808 -33.892 17.553  1   91.32  ? 388 LYS D NZ  1 
ATOM   8614 N  N   . PRO D 2 219 ? -52.357 -28.815 20.394  1   75.86  ? 389 PRO D N   1 
ATOM   8615 C  CA  . PRO D 2 219 ? -51.107 -29.299 20.977  1   74     ? 389 PRO D CA  1 
ATOM   8616 C  C   . PRO D 2 219 ? -50.974 -28.88  22.439  1   70.98  ? 389 PRO D C   1 
ATOM   8617 O  O   . PRO D 2 219 ? -50.826 -29.733 23.309  1   72.35  ? 389 PRO D O   1 
ATOM   8618 C  CB  . PRO D 2 219 ? -50.048 -28.682 20.049  1   72.46  ? 389 PRO D CB  1 
ATOM   8619 C  CG  . PRO D 2 219 ? -50.737 -28.717 18.713  1   72.88  ? 389 PRO D CG  1 
ATOM   8620 C  CD  . PRO D 2 219 ? -52.153 -28.234 19.054  1   74.76  ? 389 PRO D CD  1 
ATOM   8621 N  N   . CYS D 2 220 ? -51.107 -27.574 22.698  1   67.42  ? 390 CYS D N   1 
ATOM   8622 C  CA  . CYS D 2 220 ? -50.875 -27.029 24.023  1   61.29  ? 390 CYS D CA  1 
ATOM   8623 C  C   . CYS D 2 220 ? -51.924 -27.563 24.991  1   60.7   ? 390 CYS D C   1 
ATOM   8624 O  O   . CYS D 2 220 ? -51.579 -27.99  26.097  1   58.74  ? 390 CYS D O   1 
ATOM   8625 C  CB  . CYS D 2 220 ? -50.905 -25.504 24.016  1   60.34  ? 390 CYS D CB  1 
ATOM   8626 S  SG  . CYS D 2 220 ? -50.328 -24.761 25.567  1   57.9   ? 390 CYS D SG  1 
ATOM   8627 N  N   . LEU D 2 221 ? -53.196 -27.518 24.566  1   61.6   ? 391 LEU D N   1 
ATOM   8628 C  CA  . LEU D 2 221 ? -54.273 -28.1   25.352  1   64.17  ? 391 LEU D CA  1 
ATOM   8629 C  C   . LEU D 2 221 ? -53.885 -29.513 25.783  1   62.88  ? 391 LEU D C   1 
ATOM   8630 O  O   . LEU D 2 221 ? -53.94  -29.82  26.976  1   59.62  ? 391 LEU D O   1 
ATOM   8631 C  CB  . LEU D 2 221 ? -55.645 -28.074 24.672  1   70.34  ? 391 LEU D CB  1 
ATOM   8632 C  CG  . LEU D 2 221 ? -56.574 -26.903 25.019  1   73.13  ? 391 LEU D CG  1 
ATOM   8633 C  CD1 . LEU D 2 221 ? -57.935 -27.178 24.41   1   76.21  ? 391 LEU D CD1 1 
ATOM   8634 C  CD2 . LEU D 2 221 ? -56.71  -26.643 26.522  1   71.57  ? 391 LEU D CD2 1 
ATOM   8635 N  N   . LEU D 2 222 ? -53.465 -30.336 24.803  1   65.39  ? 392 LEU D N   1 
ATOM   8636 C  CA  . LEU D 2 222 ? -53.092 -31.727 25.05   1   69.2   ? 392 LEU D CA  1 
ATOM   8637 C  C   . LEU D 2 222 ? -52.029 -31.783 26.152  1   66.19  ? 392 LEU D C   1 
ATOM   8638 O  O   . LEU D 2 222 ? -52.257 -32.416 27.184  1   67.51  ? 392 LEU D O   1 
ATOM   8639 C  CB  . LEU D 2 222 ? -52.686 -32.549 23.818  1   70.18  ? 392 LEU D CB  1 
ATOM   8640 C  CG  . LEU D 2 222 ? -53.771 -32.911 22.787  1   74.9   ? 392 LEU D CG  1 
ATOM   8641 C  CD1 . LEU D 2 222 ? -53.229 -33.903 21.746  1   75.34  ? 392 LEU D CD1 1 
ATOM   8642 C  CD2 . LEU D 2 222 ? -55.158 -33.351 23.313  1   75.15  ? 392 LEU D CD2 1 
ATOM   8643 N  N   . ASP D 2 223 ? -50.896 -31.095 25.928  1   62.96  ? 393 ASP D N   1 
ATOM   8644 C  CA  . ASP D 2 223 ? -49.761 -31.062 26.842  1   61.32  ? 393 ASP D CA  1 
ATOM   8645 C  C   . ASP D 2 223 ? -50.182 -30.668 28.256  1   62.06  ? 393 ASP D C   1 
ATOM   8646 O  O   . ASP D 2 223 ? -49.719 -31.279 29.224  1   64.54  ? 393 ASP D O   1 
ATOM   8647 C  CB  . ASP D 2 223 ? -48.624 -30.19  26.334  1   58.34  ? 393 ASP D CB  1 
ATOM   8648 C  CG  . ASP D 2 223 ? -47.639 -30.895 25.425  1   60.86  ? 393 ASP D CG  1 
ATOM   8649 O  OD1 . ASP D 2 223 ? -47.566 -32.134 25.511  1   70.1   ? 393 ASP D OD1 1 
ATOM   8650 O  OD2 . ASP D 2 223 ? -46.977 -30.215 24.619  1   59.54  ? 393 ASP D OD2 1 
ATOM   8651 N  N   . LEU D 2 224 ? -51.05  -29.651 28.365  1   59.53  ? 394 LEU D N   1 
ATOM   8652 C  CA  . LEU D 2 224 ? -51.39  -29.06  29.651  1   57.95  ? 394 LEU D CA  1 
ATOM   8653 C  C   . LEU D 2 224 ? -52.383 -29.949 30.398  1   62.16  ? 394 LEU D C   1 
ATOM   8654 O  O   . LEU D 2 224 ? -52.399 -29.981 31.637  1   59.68  ? 394 LEU D O   1 
ATOM   8655 C  CB  . LEU D 2 224 ? -51.914 -27.639 29.443  1   55.94  ? 394 LEU D CB  1 
ATOM   8656 C  CG  . LEU D 2 224 ? -52.012 -26.743 30.686  1   53.05  ? 394 LEU D CG  1 
ATOM   8657 C  CD1 . LEU D 2 224 ? -50.7   -26.536 31.406  1   49.74  ? 394 LEU D CD1 1 
ATOM   8658 C  CD2 . LEU D 2 224 ? -52.574 -25.386 30.309  1   52.06  ? 394 LEU D CD2 1 
ATOM   8659 N  N   . HIS D 2 225 ? -53.208 -30.668 29.623  1   65.45  ? 395 HIS D N   1 
ATOM   8660 C  CA  . HIS D 2 225 ? -54.172 -31.591 30.187  1   68.79  ? 395 HIS D CA  1 
ATOM   8661 C  C   . HIS D 2 225 ? -53.41  -32.68  30.937  1   72.27  ? 395 HIS D C   1 
ATOM   8662 O  O   . HIS D 2 225 ? -53.781 -33.042 32.053  1   76.43  ? 395 HIS D O   1 
ATOM   8663 C  CB  . HIS D 2 225 ? -55.101 -32.131 29.095  1   71.72  ? 395 HIS D CB  1 
ATOM   8664 C  CG  . HIS D 2 225 ? -56.069 -33.162 29.583  1   73.86  ? 395 HIS D CG  1 
ATOM   8665 N  ND1 . HIS D 2 225 ? -56.799 -32.999 30.743  1   73.97  ? 395 HIS D ND1 1 
ATOM   8666 C  CD2 . HIS D 2 225 ? -56.428 -34.347 29.084  1   74.55  ? 395 HIS D CD2 1 
ATOM   8667 C  CE1 . HIS D 2 225 ? -57.564 -34.057 30.939  1   74.73  ? 395 HIS D CE1 1 
ATOM   8668 N  NE2 . HIS D 2 225 ? -57.357 -34.885 29.942  1   76.79  ? 395 HIS D NE2 1 
ATOM   8669 N  N   . GLN D 2 226 ? -52.338 -33.182 30.311  1   72.49  ? 396 GLN D N   1 
ATOM   8670 C  CA  . GLN D 2 226 ? -51.469 -34.183 30.913  1   73.07  ? 396 GLN D CA  1 
ATOM   8671 C  C   . GLN D 2 226 ? -50.773 -33.618 32.148  1   67.95  ? 396 GLN D C   1 
ATOM   8672 O  O   . GLN D 2 226 ? -50.778 -34.254 33.201  1   68.19  ? 396 GLN D O   1 
ATOM   8673 C  CB  . GLN D 2 226 ? -50.379 -34.613 29.941  1   75.74  ? 396 GLN D CB  1 
ATOM   8674 C  CG  . GLN D 2 226 ? -50.853 -35.598 28.883  1   85.32  ? 396 GLN D CG  1 
ATOM   8675 C  CD  . GLN D 2 226 ? -49.682 -36.3   28.234  1   91.61  ? 396 GLN D CD  1 
ATOM   8676 O  OE1 . GLN D 2 226 ? -49.836 -37.329 27.569  1   97.98  ? 396 GLN D OE1 1 
ATOM   8677 N  NE2 . GLN D 2 226 ? -48.489 -35.764 28.458  1   84.38  ? 396 GLN D NE2 1 
ATOM   8678 N  N   . THR D 2 227 ? -50.179 -32.427 32.005  1   61.29  ? 397 THR D N   1 
ATOM   8679 C  CA  . THR D 2 227 ? -49.535 -31.767 33.131  1   58.17  ? 397 THR D CA  1 
ATOM   8680 C  C   . THR D 2 227 ? -50.526 -31.705 34.292  1   57.56  ? 397 THR D C   1 
ATOM   8681 O  O   . THR D 2 227 ? -50.177 -32.074 35.413  1   56.45  ? 397 THR D O   1 
ATOM   8682 C  CB  . THR D 2 227 ? -48.974 -30.396 32.735  1   54.92  ? 397 THR D CB  1 
ATOM   8683 O  OG1 . THR D 2 227 ? -47.968 -30.632 31.755  1   53.31  ? 397 THR D OG1 1 
ATOM   8684 C  CG2 . THR D 2 227 ? -48.304 -29.661 33.882  1   52.29  ? 397 THR D CG2 1 
ATOM   8685 N  N   . TYR D 2 228 ? -51.77  -31.294 34.002  1   57.56  ? 398 TYR D N   1 
ATOM   8686 C  CA  . TYR D 2 228 ? -52.772 -31.182 35.047  1   60.09  ? 398 TYR D CA  1 
ATOM   8687 C  C   . TYR D 2 228 ? -52.97  -32.562 35.661  1   65.71  ? 398 TYR D C   1 
ATOM   8688 O  O   . TYR D 2 228 ? -53.037 -32.711 36.887  1   68.31  ? 398 TYR D O   1 
ATOM   8689 C  CB  . TYR D 2 228 ? -54.061 -30.569 34.49   1   60.59  ? 398 TYR D CB  1 
ATOM   8690 C  CG  . TYR D 2 228 ? -55.145 -30.183 35.495  1   63.14  ? 398 TYR D CG  1 
ATOM   8691 C  CD1 . TYR D 2 228 ? -54.945 -30.255 36.876  1   63.46  ? 398 TYR D CD1 1 
ATOM   8692 C  CD2 . TYR D 2 228 ? -56.379 -29.705 35.05   1   65.16  ? 398 TYR D CD2 1 
ATOM   8693 C  CE1 . TYR D 2 228 ? -55.945 -29.886 37.77   1   64.81  ? 398 TYR D CE1 1 
ATOM   8694 C  CE2 . TYR D 2 228 ? -57.376 -29.311 35.93   1   64.43  ? 398 TYR D CE2 1 
ATOM   8695 C  CZ  . TYR D 2 228 ? -57.16  -29.41  37.293  1   65.15  ? 398 TYR D CZ  1 
ATOM   8696 O  OH  . TYR D 2 228 ? -58.159 -29.035 38.143  1   66.51  ? 398 TYR D OH  1 
ATOM   8697 N  N   . LEU D 2 229 ? -53.038 -33.565 34.778  1   68.22  ? 399 LEU D N   1 
ATOM   8698 C  CA  . LEU D 2 229 ? -53.443 -34.905 35.161  1   71.96  ? 399 LEU D CA  1 
ATOM   8699 C  C   . LEU D 2 229 ? -52.379 -35.533 36.053  1   72.46  ? 399 LEU D C   1 
ATOM   8700 O  O   . LEU D 2 229 ? -52.721 -36.179 37.042  1   73.19  ? 399 LEU D O   1 
ATOM   8701 C  CB  . LEU D 2 229 ? -53.717 -35.752 33.922  1   72.9   ? 399 LEU D CB  1 
ATOM   8702 C  CG  . LEU D 2 229 ? -55.159 -35.764 33.413  1   74.33  ? 399 LEU D CG  1 
ATOM   8703 C  CD1 . LEU D 2 229 ? -55.141 -36.364 32.026  1   75.87  ? 399 LEU D CD1 1 
ATOM   8704 C  CD2 . LEU D 2 229 ? -56.011 -36.615 34.332  1   75.01  ? 399 LEU D CD2 1 
ATOM   8705 N  N   . ARG D 2 230 ? -51.104 -35.315 35.695  1   70.72  ? 400 ARG D N   1 
ATOM   8706 C  CA  . ARG D 2 230 ? -49.963 -35.92  36.373  1   73.19  ? 400 ARG D CA  1 
ATOM   8707 C  C   . ARG D 2 230 ? -49.465 -35.051 37.535  1   69.62  ? 400 ARG D C   1 
ATOM   8708 O  O   . ARG D 2 230 ? -48.534 -35.461 38.236  1   66.2   ? 400 ARG D O   1 
ATOM   8709 C  CB  . ARG D 2 230 ? -48.844 -36.258 35.378  1   76.08  ? 400 ARG D CB  1 
ATOM   8710 C  CG  . ARG D 2 230 ? -48.995 -37.617 34.709  1   88.75  ? 400 ARG D CG  1 
ATOM   8711 C  CD  . ARG D 2 230 ? -48.287 -37.681 33.351  1   96.53  ? 400 ARG D CD  1 
ATOM   8712 N  NE  . ARG D 2 230 ? -48.591 -38.927 32.628  1   107.73 ? 400 ARG D NE  1 
ATOM   8713 C  CZ  . ARG D 2 230 ? -48.466 -39.154 31.316  1   104.92 ? 400 ARG D CZ  1 
ATOM   8714 N  NH1 . ARG D 2 230 ? -48.084 -38.181 30.507  1   101    ? 400 ARG D NH1 1 
ATOM   8715 N  NH2 . ARG D 2 230 ? -48.733 -40.353 30.818  1   99.15  ? 400 ARG D NH2 1 
ATOM   8716 N  N   . ALA D 2 231 ? -50.114 -33.889 37.751  1   65.48  ? 401 ALA D N   1 
ATOM   8717 C  CA  . ALA D 2 231 ? -49.68  -32.866 38.699  1   61.32  ? 401 ALA D CA  1 
ATOM   8718 C  C   . ALA D 2 231 ? -49.347 -33.439 40.081  1   62.28  ? 401 ALA D C   1 
ATOM   8719 O  O   . ALA D 2 231 ? -48.262 -33.159 40.596  1   63.84  ? 401 ALA D O   1 
ATOM   8720 C  CB  . ALA D 2 231 ? -50.683 -31.738 38.783  1   57.94  ? 401 ALA D CB  1 
ATOM   8721 N  N   . PRO D 2 232 ? -50.229 -34.243 40.733  1   63.77  ? 402 PRO D N   1 
ATOM   8722 C  CA  . PRO D 2 232 ? -49.929 -34.8   42.059  1   65.02  ? 402 PRO D CA  1 
ATOM   8723 C  C   . PRO D 2 232 ? -48.729 -35.741 42.202  1   67.61  ? 402 PRO D C   1 
ATOM   8724 O  O   . PRO D 2 232 ? -48.332 -36.049 43.324  1   70.1   ? 402 PRO D O   1 
ATOM   8725 C  CB  . PRO D 2 232 ? -51.246 -35.485 42.495  1   65.76  ? 402 PRO D CB  1 
ATOM   8726 C  CG  . PRO D 2 232 ? -52.301 -34.905 41.576  1   65.45  ? 402 PRO D CG  1 
ATOM   8727 C  CD  . PRO D 2 232 ? -51.576 -34.627 40.266  1   64.39  ? 402 PRO D CD  1 
ATOM   8728 N  N   . GLN D 2 233 ? -48.171 -36.204 41.07   1   67.25  ? 403 GLN D N   1 
ATOM   8729 C  CA  . GLN D 2 233 ? -47.02  -37.1   41.061  1   67.78  ? 403 GLN D CA  1 
ATOM   8730 C  C   . GLN D 2 233 ? -45.756 -36.339 40.656  1   63.68  ? 403 GLN D C   1 
ATOM   8731 O  O   . GLN D 2 233 ? -44.654 -36.869 40.787  1   64.07  ? 403 GLN D O   1 
ATOM   8732 C  CB  . GLN D 2 233 ? -47.183 -38.343 40.173  1   71.92  ? 403 GLN D CB  1 
ATOM   8733 C  CG  . GLN D 2 233 ? -48.009 -39.48  40.775  1   77.53  ? 403 GLN D CG  1 
ATOM   8734 C  CD  . GLN D 2 233 ? -49.501 -39.21  40.848  1   81.16  ? 403 GLN D CD  1 
ATOM   8735 O  OE1 . GLN D 2 233 ? -50.207 -39.734 41.718  1   84.93  ? 403 GLN D OE1 1 
ATOM   8736 N  NE2 . GLN D 2 233 ? -50.009 -38.379 39.948  1   79.02  ? 403 GLN D NE2 1 
ATOM   8737 N  N   . HIS D 2 234 ? -45.906 -35.1   40.169  1   59.57  ? 404 HIS D N   1 
ATOM   8738 C  CA  . HIS D 2 234 ? -44.746 -34.297 39.812  1   54.67  ? 404 HIS D CA  1 
ATOM   8739 C  C   . HIS D 2 234 ? -43.839 -34.136 41.032  1   53.54  ? 404 HIS D C   1 
ATOM   8740 O  O   . HIS D 2 234 ? -44.32  -34.109 42.153  1   58.75  ? 404 HIS D O   1 
ATOM   8741 C  CB  . HIS D 2 234 ? -45.203 -32.983 39.184  1   51.47  ? 404 HIS D CB  1 
ATOM   8742 C  CG  . HIS D 2 234 ? -44.141 -32.302 38.38   1   49.8   ? 404 HIS D CG  1 
ATOM   8743 N  ND1 . HIS D 2 234 ? -42.9   -31.956 38.881  1   49.13  ? 404 HIS D ND1 1 
ATOM   8744 C  CD2 . HIS D 2 234 ? -44.159 -31.863 37.115  1   48.81  ? 404 HIS D CD2 1 
ATOM   8745 C  CE1 . HIS D 2 234 ? -42.191 -31.345 37.946  1   46.13  ? 404 HIS D CE1 1 
ATOM   8746 N  NE2 . HIS D 2 234 ? -42.943 -31.262 36.87   1   47.3   ? 404 HIS D NE2 1 
ATOM   8747 N  N   . ALA D 2 235 ? -42.525 -34.075 40.822  1   50.82  ? 405 ALA D N   1 
ATOM   8748 C  CA  . ALA D 2 235 ? -41.574 -33.901 41.909  1   51.21  ? 405 ALA D CA  1 
ATOM   8749 C  C   . ALA D 2 235 ? -41.683 -32.495 42.499  1   51.44  ? 405 ALA D C   1 
ATOM   8750 O  O   . ALA D 2 235 ? -41.161 -32.232 43.583  1   50.99  ? 405 ALA D O   1 
ATOM   8751 C  CB  . ALA D 2 235 ? -40.164 -34.195 41.43   1   49.23  ? 405 ALA D CB  1 
ATOM   8752 N  N   . GLN D 2 236 ? -42.383 -31.608 41.782  1   51.4   ? 406 GLN D N   1 
ATOM   8753 C  CA  . GLN D 2 236 ? -42.585 -30.228 42.197  1   51.8   ? 406 GLN D CA  1 
ATOM   8754 C  C   . GLN D 2 236 ? -44.041 -30.019 42.611  1   53.06  ? 406 GLN D C   1 
ATOM   8755 O  O   . GLN D 2 236 ? -44.961 -30.199 41.815  1   56.91  ? 406 GLN D O   1 
ATOM   8756 C  CB  . GLN D 2 236 ? -42.087 -29.283 41.105  1   50.99  ? 406 GLN D CB  1 
ATOM   8757 C  CG  . GLN D 2 236 ? -40.649 -28.794 41.268  1   51.87  ? 406 GLN D CG  1 
ATOM   8758 C  CD  . GLN D 2 236 ? -39.595 -29.876 41.298  1   55.96  ? 406 GLN D CD  1 
ATOM   8759 O  OE1 . GLN D 2 236 ? -39.339 -30.547 40.297  1   63.64  ? 406 GLN D OE1 1 
ATOM   8760 N  NE2 . GLN D 2 236 ? -38.954 -30.045 42.444  1   57.05  ? 406 GLN D NE2 1 
ATOM   8761 N  N   . GLN D 2 237 ? -44.211 -29.587 43.867  1   53.92  ? 407 GLN D N   1 
ATOM   8762 C  CA  . GLN D 2 237 ? -45.479 -29.554 44.573  1   54.23  ? 407 GLN D CA  1 
ATOM   8763 C  C   . GLN D 2 237 ? -45.785 -28.182 45.189  1   55.44  ? 407 GLN D C   1 
ATOM   8764 O  O   . GLN D 2 237 ? -46.844 -28.043 45.796  1   60.63  ? 407 GLN D O   1 
ATOM   8765 C  CB  . GLN D 2 237 ? -45.428 -30.576 45.709  1   55.54  ? 407 GLN D CB  1 
ATOM   8766 C  CG  . GLN D 2 237 ? -45.549 -32.027 45.251  1   58.52  ? 407 GLN D CG  1 
ATOM   8767 C  CD  . GLN D 2 237 ? -46.76  -32.285 44.382  1   58.76  ? 407 GLN D CD  1 
ATOM   8768 O  OE1 . GLN D 2 237 ? -47.881 -31.883 44.709  1   61.01  ? 407 GLN D OE1 1 
ATOM   8769 N  NE2 . GLN D 2 237 ? -46.542 -32.938 43.251  1   57.46  ? 407 GLN D NE2 1 
ATOM   8770 N  N   . SER D 2 238 ? -44.907 -27.171 45.057  1   50.65  ? 408 SER D N   1 
ATOM   8771 C  CA  . SER D 2 238 ? -45.202 -25.855 45.626  1   51.51  ? 408 SER D CA  1 
ATOM   8772 C  C   . SER D 2 238 ? -46.449 -25.18  45.055  1   52.79  ? 408 SER D C   1 
ATOM   8773 O  O   . SER D 2 238 ? -47.184 -24.531 45.804  1   54.12  ? 408 SER D O   1 
ATOM   8774 C  CB  . SER D 2 238 ? -44.058 -24.934 45.544  1   48.24  ? 408 SER D CB  1 
ATOM   8775 O  OG  . SER D 2 238 ? -43.028 -25.482 46.342  1   52.74  ? 408 SER D OG  1 
ATOM   8776 N  N   . ILE D 2 239 ? -46.657 -25.303 43.737  1   51.63  ? 409 ILE D N   1 
ATOM   8777 C  CA  . ILE D 2 239 ? -47.772 -24.662 43.056  1   50.52  ? 409 ILE D CA  1 
ATOM   8778 C  C   . ILE D 2 239 ? -49.091 -25.255 43.551  1   54.76  ? 409 ILE D C   1 
ATOM   8779 O  O   . ILE D 2 239 ? -50.005 -24.523 43.944  1   58.05  ? 409 ILE D O   1 
ATOM   8780 C  CB  . ILE D 2 239 ? -47.61  -24.789 41.536  1   46.71  ? 409 ILE D CB  1 
ATOM   8781 C  CG1 . ILE D 2 239 ? -46.369 -24.009 41.074  1   44.08  ? 409 ILE D CG1 1 
ATOM   8782 C  CG2 . ILE D 2 239 ? -48.889 -24.327 40.846  1   45.67  ? 409 ILE D CG2 1 
ATOM   8783 C  CD1 . ILE D 2 239 ? -46.051 -24.067 39.587  1   43.37  ? 409 ILE D CD1 1 
ATOM   8784 N  N   . ARG D 2 240 ? -49.17  -26.589 43.563  1   56.17  ? 410 ARG D N   1 
ATOM   8785 C  CA  . ARG D 2 240 ? -50.337 -27.27  44.109  1   58.3   ? 410 ARG D CA  1 
ATOM   8786 C  C   . ARG D 2 240 ? -50.541 -26.88  45.574  1   59.68  ? 410 ARG D C   1 
ATOM   8787 O  O   . ARG D 2 240 ? -51.669 -26.611 45.98   1   62.59  ? 410 ARG D O   1 
ATOM   8788 C  CB  . ARG D 2 240 ? -50.23  -28.792 43.962  1   59.86  ? 410 ARG D CB  1 
ATOM   8789 C  CG  . ARG D 2 240 ? -50.363 -29.32  42.54   1   58.6   ? 410 ARG D CG  1 
ATOM   8790 C  CD  . ARG D 2 240 ? -50.433 -30.838 42.587  1   59.7   ? 410 ARG D CD  1 
ATOM   8791 N  NE  . ARG D 2 240 ? -51.749 -31.283 43.051  1   61.69  ? 410 ARG D NE  1 
ATOM   8792 C  CZ  . ARG D 2 240 ? -51.996 -32.012 44.122  1   63.66  ? 410 ARG D CZ  1 
ATOM   8793 N  NH1 . ARG D 2 240 ? -53.227 -32.42  44.359  1   64.96  ? 410 ARG D NH1 1 
ATOM   8794 N  NH2 . ARG D 2 240 ? -51.013 -32.35  44.936  1   62.79  ? 410 ARG D NH2 1 
ATOM   8795 N  N   . GLU D 2 241 ? -49.446 -26.843 46.349  1   60.45  ? 411 GLU D N   1 
ATOM   8796 C  CA  . GLU D 2 241 ? -49.46  -26.422 47.746  1   63.74  ? 411 GLU D CA  1 
ATOM   8797 C  C   . GLU D 2 241 ? -50.07  -25.03  47.883  1   63.41  ? 411 GLU D C   1 
ATOM   8798 O  O   . GLU D 2 241 ? -51.003 -24.845 48.67   1   66.27  ? 411 GLU D O   1 
ATOM   8799 C  CB  . GLU D 2 241 ? -48.112 -26.545 48.46   1   66.38  ? 411 GLU D CB  1 
ATOM   8800 C  CG  . GLU D 2 241 ? -47.956 -27.861 49.216  1   78.44  ? 411 GLU D CG  1 
ATOM   8801 C  CD  . GLU D 2 241 ? -49.193 -28.228 50.036  1   91.09  ? 411 GLU D CD  1 
ATOM   8802 O  OE1 . GLU D 2 241 ? -49.644 -27.367 50.836  1   98     ? 411 GLU D OE1 1 
ATOM   8803 O  OE2 . GLU D 2 241 ? -49.725 -29.357 49.871  1   88.67  ? 411 GLU D OE2 1 
ATOM   8804 N  N   . LYS D 2 242 ? -49.523 -24.08  47.112  1   58.43  ? 412 LYS D N   1 
ATOM   8805 C  CA  . LYS D 2 242 ? -50     -22.708 46.999  1   58.94  ? 412 LYS D CA  1 
ATOM   8806 C  C   . LYS D 2 242 ? -51.51  -22.631 46.759  1   59.3   ? 412 LYS D C   1 
ATOM   8807 O  O   . LYS D 2 242 ? -52.205 -21.907 47.471  1   57.62  ? 412 LYS D O   1 
ATOM   8808 C  CB  . LYS D 2 242 ? -49.23  -22.012 45.872  1   55.67  ? 412 LYS D CB  1 
ATOM   8809 C  CG  . LYS D 2 242 ? -49.681 -20.616 45.506  1   53.59  ? 412 LYS D CG  1 
ATOM   8810 C  CD  . LYS D 2 242 ? -48.655 -19.973 44.581  1   49.15  ? 412 LYS D CD  1 
ATOM   8811 C  CE  . LYS D 2 242 ? -49.041 -18.654 44.006  1   46.36  ? 412 LYS D CE  1 
ATOM   8812 N  NZ  . LYS D 2 242 ? -47.983 -18.216 43.092  1   44.8   ? 412 LYS D NZ  1 
ATOM   8813 N  N   . TYR D 2 243 ? -52.019 -23.379 45.77   1   60.64  ? 413 TYR D N   1 
ATOM   8814 C  CA  . TYR D 2 243 ? -53.414 -23.23  45.36   1   64.28  ? 413 TYR D CA  1 
ATOM   8815 C  C   . TYR D 2 243 ? -54.377 -24.189 46.074  1   67.07  ? 413 TYR D C   1 
ATOM   8816 O  O   . TYR D 2 243 ? -55.486 -24.423 45.593  1   66.11  ? 413 TYR D O   1 
ATOM   8817 C  CB  . TYR D 2 243 ? -53.54  -23.397 43.847  1   62.23  ? 413 TYR D CB  1 
ATOM   8818 C  CG  . TYR D 2 243 ? -52.996 -22.232 43.045  1   59.93  ? 413 TYR D CG  1 
ATOM   8819 C  CD1 . TYR D 2 243 ? -51.626 -22.085 42.841  1   59.89  ? 413 TYR D CD1 1 
ATOM   8820 C  CD2 . TYR D 2 243 ? -53.851 -21.303 42.466  1   59     ? 413 TYR D CD2 1 
ATOM   8821 C  CE1 . TYR D 2 243 ? -51.118 -21.036 42.09   1   57.52  ? 413 TYR D CE1 1 
ATOM   8822 C  CE2 . TYR D 2 243 ? -53.356 -20.25  41.712  1   57.42  ? 413 TYR D CE2 1 
ATOM   8823 C  CZ  . TYR D 2 243 ? -51.991 -20.12  41.524  1   57.67  ? 413 TYR D CZ  1 
ATOM   8824 O  OH  . TYR D 2 243 ? -51.507 -19.093 40.771  1   60.39  ? 413 TYR D OH  1 
ATOM   8825 N  N   . LYS D 2 244 ? -53.966 -24.727 47.226  1   69.02  ? 414 LYS D N   1 
ATOM   8826 C  CA  . LYS D 2 244 ? -54.88  -25.438 48.104  1   73.11  ? 414 LYS D CA  1 
ATOM   8827 C  C   . LYS D 2 244 ? -55.567 -24.393 48.972  1   75.17  ? 414 LYS D C   1 
ATOM   8828 O  O   . LYS D 2 244 ? -56.615 -24.638 49.559  1   78.27  ? 414 LYS D O   1 
ATOM   8829 C  CB  . LYS D 2 244 ? -54.128 -26.4   49.032  1   75.23  ? 414 LYS D CB  1 
ATOM   8830 C  CG  . LYS D 2 244 ? -53.661 -27.765 48.505  1   77.02  ? 414 LYS D CG  1 
ATOM   8831 C  CD  . LYS D 2 244 ? -53.216 -28.665 49.655  1   81.99  ? 414 LYS D CD  1 
ATOM   8832 C  CE  . LYS D 2 244 ? -54.095 -28.405 50.872  1   88.17  ? 414 LYS D CE  1 
ATOM   8833 N  NZ  . LYS D 2 244 ? -53.888 -29.203 52.09   1   87.81  ? 414 LYS D NZ  1 
ATOM   8834 N  N   . ASN D 2 245 ? -54.889 -23.268 49.114  1   76.17  ? 415 ASN D N   1 
ATOM   8835 C  CA  . ASN D 2 245 ? -55.345 -22.212 50.05   1   80.87  ? 415 ASN D CA  1 
ATOM   8836 C  C   . ASN D 2 245 ? -56.667 -21.589 49.624  1   79.2   ? 415 ASN D C   1 
ATOM   8837 O  O   . ASN D 2 245 ? -57.027 -21.668 48.438  1   79.33  ? 415 ASN D O   1 
ATOM   8838 C  CB  . ASN D 2 245 ? -54.259 -21.162 50.253  1   87.23  ? 415 ASN D CB  1 
ATOM   8839 C  CG  . ASN D 2 245 ? -54.573 -20.216 51.386  1   99.03  ? 415 ASN D CG  1 
ATOM   8840 O  OD1 . ASN D 2 245 ? -55.16  -20.628 52.393  1   104.67 ? 415 ASN D OD1 1 
ATOM   8841 N  ND2 . ASN D 2 245 ? -54.216 -18.95  51.237  1   101.12 ? 415 ASN D ND2 1 
ATOM   8842 N  N   . SER D 2 246 ? -57.313 -20.936 50.559  1   78.96  ? 416 SER D N   1 
ATOM   8843 C  CA  . SER D 2 246 ? -58.643 -20.387 50.335  1   80.42  ? 416 SER D CA  1 
ATOM   8844 C  C   . SER D 2 246 ? -58.586 -19.111 49.497  1   76.49  ? 416 SER D C   1 
ATOM   8845 O  O   . SER D 2 246 ? -59.595 -18.693 48.944  1   77.52  ? 416 SER D O   1 
ATOM   8846 C  CB  . SER D 2 246 ? -59.394 -20.187 51.627  1   82.93  ? 416 SER D CB  1 
ATOM   8847 O  OG  . SER D 2 246 ? -58.653 -19.348 52.499  1   84.98  ? 416 SER D OG  1 
ATOM   8848 N  N   . LYS D 2 247 ? -57.397 -18.512 49.397  1   74.31  ? 417 LYS D N   1 
ATOM   8849 C  CA  . LYS D 2 247 ? -57.163 -17.32  48.598  1   73.33  ? 417 LYS D CA  1 
ATOM   8850 C  C   . LYS D 2 247 ? -57.388 -17.618 47.115  1   72.57  ? 417 LYS D C   1 
ATOM   8851 O  O   . LYS D 2 247 ? -57.825 -16.74  46.361  1   67.67  ? 417 LYS D O   1 
ATOM   8852 C  CB  . LYS D 2 247 ? -55.747 -16.819 48.908  1   74.57  ? 417 LYS D CB  1 
ATOM   8853 C  CG  . LYS D 2 247 ? -55.141 -15.803 47.939  1   75.35  ? 417 LYS D CG  1 
ATOM   8854 C  CD  . LYS D 2 247 ? -53.952 -15.005 48.472  1   78.58  ? 417 LYS D CD  1 
ATOM   8855 C  CE  . LYS D 2 247 ? -52.818 -15.885 48.907  1   85.57  ? 417 LYS D CE  1 
ATOM   8856 N  NZ  . LYS D 2 247 ? -51.726 -15.187 49.594  1   86.98  ? 417 LYS D NZ  1 
ATOM   8857 N  N   . TYR D 2 248 ? -57.042 -18.853 46.707  1   75.21  ? 418 TYR D N   1 
ATOM   8858 C  CA  . TYR D 2 248 ? -57.235 -19.336 45.342  1   75.06  ? 418 TYR D CA  1 
ATOM   8859 C  C   . TYR D 2 248 ? -58.406 -20.313 45.305  1   76.36  ? 418 TYR D C   1 
ATOM   8860 O  O   . TYR D 2 248 ? -58.591 -20.997 44.298  1   80.83  ? 418 TYR D O   1 
ATOM   8861 C  CB  . TYR D 2 248 ? -55.982 -19.878 44.635  1   69.35  ? 418 TYR D CB  1 
ATOM   8862 C  CG  . TYR D 2 248 ? -54.809 -18.907 44.703  1   67.8   ? 418 TYR D CG  1 
ATOM   8863 C  CD1 . TYR D 2 248 ? -54.706 -17.816 43.839  1   65.93  ? 418 TYR D CD1 1 
ATOM   8864 C  CD2 . TYR D 2 248 ? -53.826 -19.054 45.678  1   66.21  ? 418 TYR D CD2 1 
ATOM   8865 C  CE1 . TYR D 2 248 ? -53.649 -16.919 43.934  1   64.4   ? 418 TYR D CE1 1 
ATOM   8866 C  CE2 . TYR D 2 248 ? -52.777 -18.159 45.795  1   63.84  ? 418 TYR D CE2 1 
ATOM   8867 C  CZ  . TYR D 2 248 ? -52.679 -17.096 44.914  1   65.14  ? 418 TYR D CZ  1 
ATOM   8868 O  OH  . TYR D 2 248 ? -51.612 -16.253 45.074  1   63.66  ? 418 TYR D OH  1 
ATOM   8869 N  N   . HIS D 2 249 ? -59.178 -20.368 46.401  1   75.98  ? 419 HIS D N   1 
ATOM   8870 C  CA  . HIS D 2 249 ? -60.45  -21.081 46.456  1   79.3   ? 419 HIS D CA  1 
ATOM   8871 C  C   . HIS D 2 249 ? -60.265 -22.586 46.288  1   78.92  ? 419 HIS D C   1 
ATOM   8872 O  O   . HIS D 2 249 ? -61.146 -23.249 45.754  1   79.97  ? 419 HIS D O   1 
ATOM   8873 C  CB  . HIS D 2 249 ? -61.429 -20.535 45.409  1   83.62  ? 419 HIS D CB  1 
ATOM   8874 C  CG  . HIS D 2 249 ? -61.583 -19.048 45.464  1   90.25  ? 419 HIS D CG  1 
ATOM   8875 N  ND1 . HIS D 2 249 ? -60.887 -18.18  44.647  1   89.98  ? 419 HIS D ND1 1 
ATOM   8876 C  CD2 . HIS D 2 249 ? -62.347 -18.274 46.252  1   94.95  ? 419 HIS D CD2 1 
ATOM   8877 C  CE1 . HIS D 2 249 ? -61.23  -16.928 44.935  1   93.74  ? 419 HIS D CE1 1 
ATOM   8878 N  NE2 . HIS D 2 249 ? -62.115 -16.959 45.909  1   95.5   ? 419 HIS D NE2 1 
ATOM   8879 N  N   . GLY D 2 250 ? -59.1   -23.098 46.704  1   79.66  ? 420 GLY D N   1 
ATOM   8880 C  CA  . GLY D 2 250 ? -58.818 -24.521 46.84   1   81.26  ? 420 GLY D CA  1 
ATOM   8881 C  C   . GLY D 2 250 ? -58.72  -25.319 45.532  1   80.53  ? 420 GLY D C   1 
ATOM   8882 O  O   . GLY D 2 250 ? -58.825 -26.547 45.577  1   83.96  ? 420 GLY D O   1 
ATOM   8883 N  N   . VAL D 2 251 ? -58.449 -24.655 44.397  1   74.01  ? 421 VAL D N   1 
ATOM   8884 C  CA  . VAL D 2 251 ? -58.694 -25.212 43.068  1   71.17  ? 421 VAL D CA  1 
ATOM   8885 C  C   . VAL D 2 251 ? -57.712 -26.326 42.682  1   71.54  ? 421 VAL D C   1 
ATOM   8886 O  O   . VAL D 2 251 ? -58.028 -27.182 41.846  1   75.5   ? 421 VAL D O   1 
ATOM   8887 C  CB  . VAL D 2 251 ? -58.74  -24.103 42.006  1   68.03  ? 421 VAL D CB  1 
ATOM   8888 C  CG1 . VAL D 2 251 ? -59.919 -23.169 42.26   1   69.21  ? 421 VAL D CG1 1 
ATOM   8889 C  CG2 . VAL D 2 251 ? -57.424 -23.329 41.945  1   61.19  ? 421 VAL D CG2 1 
ATOM   8890 N  N   . SER D 2 252 ? -56.515 -26.328 43.275  1   67.16  ? 422 SER D N   1 
ATOM   8891 C  CA  . SER D 2 252 ? -55.599 -27.445 43.095  1   64.86  ? 422 SER D CA  1 
ATOM   8892 C  C   . SER D 2 252 ? -56.18  -28.759 43.655  1   68.05  ? 422 SER D C   1 
ATOM   8893 O  O   . SER D 2 252 ? -55.574 -29.815 43.489  1   67.61  ? 422 SER D O   1 
ATOM   8894 C  CB  . SER D 2 252 ? -54.258 -27.127 43.698  1   60.3   ? 422 SER D CB  1 
ATOM   8895 O  OG  . SER D 2 252 ? -54.333 -27.182 45.115  1   60.88  ? 422 SER D OG  1 
ATOM   8896 N  N   . LEU D 2 253 ? -57.35  -28.698 44.312  1   68.79  ? 423 LEU D N   1 
ATOM   8897 C  CA  . LEU D 2 253 ? -58.002 -29.857 44.905  1   72.2   ? 423 LEU D CA  1 
ATOM   8898 C  C   . LEU D 2 253 ? -59.105 -30.375 43.981  1   76.18  ? 423 LEU D C   1 
ATOM   8899 O  O   . LEU D 2 253 ? -59.732 -31.394 44.269  1   81     ? 423 LEU D O   1 
ATOM   8900 C  CB  . LEU D 2 253 ? -58.546 -29.548 46.302  1   73.2   ? 423 LEU D CB  1 
ATOM   8901 C  CG  . LEU D 2 253 ? -57.521 -29.373 47.431  1   72.73  ? 423 LEU D CG  1 
ATOM   8902 C  CD1 . LEU D 2 253 ? -58.133 -28.602 48.601  1   73.77  ? 423 LEU D CD1 1 
ATOM   8903 C  CD2 . LEU D 2 253 ? -56.919 -30.693 47.911  1   72.01  ? 423 LEU D CD2 1 
ATOM   8904 N  N   . LEU D 2 254 ? -59.336 -29.69  42.861  1   76.51  ? 424 LEU D N   1 
ATOM   8905 C  CA  . LEU D 2 254 ? -60.333 -30.181 41.925  1   80.16  ? 424 LEU D CA  1 
ATOM   8906 C  C   . LEU D 2 254 ? -59.78  -31.373 41.152  1   84.59  ? 424 LEU D C   1 
ATOM   8907 O  O   . LEU D 2 254 ? -58.564 -31.52  41.005  1   86.3   ? 424 LEU D O   1 
ATOM   8908 C  CB  . LEU D 2 254 ? -60.771 -29.059 40.993  1   77.85  ? 424 LEU D CB  1 
ATOM   8909 C  CG  . LEU D 2 254 ? -61.603 -27.971 41.674  1   80.49  ? 424 LEU D CG  1 
ATOM   8910 C  CD1 . LEU D 2 254 ? -61.941 -26.847 40.702  1   78.8   ? 424 LEU D CD1 1 
ATOM   8911 C  CD2 . LEU D 2 254 ? -62.859 -28.605 42.287  1   83.22  ? 424 LEU D CD2 1 
ATOM   8912 N  N   . ASN D 2 255 ? -60.695 -32.225 40.673  1   86.93  ? 425 ASN D N   1 
ATOM   8913 C  CA  . ASN D 2 255 ? -60.348 -33.297 39.755  1   85.66  ? 425 ASN D CA  1 
ATOM   8914 C  C   . ASN D 2 255 ? -60.248 -32.733 38.342  1   82.16  ? 425 ASN D C   1 
ATOM   8915 O  O   . ASN D 2 255 ? -61.168 -32.054 37.884  1   81.01  ? 425 ASN D O   1 
ATOM   8916 C  CB  . ASN D 2 255 ? -61.363 -34.433 39.789  1   92.29  ? 425 ASN D CB  1 
ATOM   8917 C  CG  . ASN D 2 255 ? -61.29  -35.214 41.077  1   96.45  ? 425 ASN D CG  1 
ATOM   8918 O  OD1 . ASN D 2 255 ? -62.249 -35.205 41.859  1   97.64  ? 425 ASN D OD1 1 
ATOM   8919 N  ND2 . ASN D 2 255 ? -60.163 -35.871 41.324  1   97.15  ? 425 ASN D ND2 1 
ATOM   8920 N  N   . PRO D 2 256 ? -59.12  -32.977 37.627  1   78.94  ? 426 PRO D N   1 
ATOM   8921 C  CA  . PRO D 2 256 ? -59.042 -32.718 36.188  1   78.32  ? 426 PRO D CA  1 
ATOM   8922 C  C   . PRO D 2 256 ? -60.051 -33.576 35.438  1   83.87  ? 426 PRO D C   1 
ATOM   8923 O  O   . PRO D 2 256 ? -60.208 -34.761 35.744  1   86.43  ? 426 PRO D O   1 
ATOM   8924 C  CB  . PRO D 2 256 ? -57.6   -33.123 35.843  1   76.03  ? 426 PRO D CB  1 
ATOM   8925 C  CG  . PRO D 2 256 ? -57.229 -34.106 36.933  1   75.93  ? 426 PRO D CG  1 
ATOM   8926 C  CD  . PRO D 2 256 ? -57.847 -33.484 38.172  1   76.6   ? 426 PRO D CD  1 
ATOM   8927 N  N   . PRO D 2 257 ? -60.737 -33.027 34.411  1   84.25  ? 427 PRO D N   1 
ATOM   8928 C  CA  . PRO D 2 257 ? -61.723 -33.815 33.676  1   86.99  ? 427 PRO D CA  1 
ATOM   8929 C  C   . PRO D 2 257 ? -60.835 -34.842 32.98   1   89.75  ? 427 PRO D C   1 
ATOM   8930 O  O   . PRO D 2 257 ? -59.751 -34.502 32.505  1   86.78  ? 427 PRO D O   1 
ATOM   8931 C  CB  . PRO D 2 257 ? -62.375 -32.808 32.722  1   85.31  ? 427 PRO D CB  1 
ATOM   8932 C  CG  . PRO D 2 257 ? -61.306 -31.75  32.541  1   82.54  ? 427 PRO D CG  1 
ATOM   8933 C  CD  . PRO D 2 257 ? -60.518 -31.688 33.843  1   79.42  ? 427 PRO D CD  1 
ATOM   8934 N  N   . GLU D 2 258 ? -61.271 -36.109 32.984  1   97.68  ? 428 GLU D N   1 
ATOM   8935 C  CA  . GLU D 2 258 ? -60.502 -37.174 32.359  1   98.66  ? 428 GLU D CA  1 
ATOM   8936 C  C   . GLU D 2 258 ? -60.371 -36.899 30.863  1   96.97  ? 428 GLU D C   1 
ATOM   8937 O  O   . GLU D 2 258 ? -59.406 -37.355 30.253  1   92.27  ? 428 GLU D O   1 
ATOM   8938 C  CB  . GLU D 2 258 ? -61.087 -38.579 32.527  1   106.26 ? 428 GLU D CB  1 
ATOM   8939 C  CG  . GLU D 2 258 ? -61.194 -39.069 33.97   1   110.5  ? 428 GLU D CG  1 
ATOM   8940 C  CD  . GLU D 2 258 ? -62.52  -38.751 34.64   1   114.5  ? 428 GLU D CD  1 
ATOM   8941 O  OE1 . GLU D 2 258 ? -62.838 -37.542 34.806  1   109.76 ? 428 GLU D OE1 1 
ATOM   8942 O  OE2 . GLU D 2 258 ? -63.245 -39.728 34.97   1   118.27 ? 428 GLU D OE2 1 
ATOM   8943 N  N   . THR D 2 259 ? -61.324 -36.14  30.291  1   98.75  ? 429 THR D N   1 
ATOM   8944 C  CA  . THR D 2 259 ? -61.403 -36     28.843  1   101.88 ? 429 THR D CA  1 
ATOM   8945 C  C   . THR D 2 259 ? -61.844 -34.596 28.415  1   101.8  ? 429 THR D C   1 
ATOM   8946 O  O   . THR D 2 259 ? -62.674 -33.964 29.069  1   102.54 ? 429 THR D O   1 
ATOM   8947 C  CB  . THR D 2 259 ? -62.287 -37.108 28.266  1   108.76 ? 429 THR D CB  1 
ATOM   8948 O  OG1 . THR D 2 259 ? -62.044 -37.019 26.867  1   110    ? 429 THR D OG1 1 
ATOM   8949 C  CG2 . THR D 2 259 ? -63.761 -36.976 28.624  1   111.98 ? 429 THR D CG2 1 
ATOM   8950 N  N   . LEU D 2 260 ? -61.256 -34.142 27.295  1   102.23 ? 430 LEU D N   1 
ATOM   8951 C  CA  . LEU D 2 260 ? -61.621 -32.939 26.554  1   102.98 ? 430 LEU D CA  1 
ATOM   8952 C  C   . LEU D 2 260 ? -62.272 -33.375 25.243  1   109.28 ? 430 LEU D C   1 
ATOM   8953 O  O   . LEU D 2 260 ? -61.871 -34.393 24.68   1   112.95 ? 430 LEU D O   1 
ATOM   8954 C  CB  . LEU D 2 260 ? -60.355 -32.146 26.228  1   99.69  ? 430 LEU D CB  1 
ATOM   8955 C  CG  . LEU D 2 260 ? -59.242 -32.105 27.281  1   95.75  ? 430 LEU D CG  1 
ATOM   8956 C  CD1 . LEU D 2 260 ? -57.974 -31.557 26.643  1   91.34  ? 430 LEU D CD1 1 
ATOM   8957 C  CD2 . LEU D 2 260 ? -59.638 -31.267 28.482  1   93.81  ? 430 LEU D CD2 1 
ATOM   8958 N  N   . ASN D 2 261 ? -63.23  -32.59  24.729  1   110.67 ? 431 ASN D N   1 
ATOM   8959 C  CA  . ASN D 2 261 ? -64.084 -33.07  23.646  1   113.13 ? 431 ASN D CA  1 
ATOM   8960 C  C   . ASN D 2 261 ? -63.907 -32.209 22.388  1   109.89 ? 431 ASN D C   1 
ATOM   8961 O  O   . ASN D 2 261 ? -63.096 -32.624 21.527  1   104.59 ? 431 ASN D O   1 
ATOM   8962 C  CB  . ASN D 2 261 ? -65.531 -33.273 24.102  1   115.87 ? 431 ASN D CB  1 
ATOM   8963 C  CG  . ASN D 2 261 ? -65.712 -34.513 24.957  1   118.23 ? 431 ASN D CG  1 
ATOM   8964 O  OD1 . ASN D 2 261 ? -66.501 -35.403 24.616  1   121.04 ? 431 ASN D OD1 1 
ATOM   8965 N  ND2 . ASN D 2 261 ? -65.009 -34.606 26.078  1   116.75 ? 431 ASN D ND2 1 
HETATM 8966 BR BR4 A BYZ E 3 .   ? -9.209  -19.791 21.775  0.5 38.1   ? 601 BYZ A BR4 1 
HETATM 8967 BR BR4 B BYZ E 3 .   ? -6.412  -21.229 22.892  0.5 39.93  ? 601 BYZ A BR4 1 
HETATM 8968 C  C4  A BYZ E 3 .   ? -9.048  -21.121 23.09   0.5 37.17  ? 601 BYZ A C4  1 
HETATM 8969 C  C4  B BYZ E 3 .   ? -8.137  -21.785 23.393  0.5 35.35  ? 601 BYZ A C4  1 
HETATM 8970 C  C5  A BYZ E 3 .   ? -7.875  -21.736 23.532  0.5 37.55  ? 601 BYZ A C5  1 
HETATM 8971 C  C5  B BYZ E 3 .   ? -8.483  -22.946 24.09   0.5 33.4   ? 601 BYZ A C5  1 
HETATM 8972 N  N1  A BYZ E 3 .   ? -8.158  -22.62  24.488  0.5 36.29  ? 601 BYZ A N1  1 
HETATM 8973 N  N1  B BYZ E 3 .   ? -9.795  -22.986 24.254  0.5 32.17  ? 601 BYZ A N1  1 
HETATM 8974 N  N2  A BYZ E 3 .   ? -9.486  -22.592 24.645  0.5 35.73  ? 601 BYZ A N2  1 
HETATM 8975 N  N2  B BYZ E 3 .   ? -10.302 -21.872 23.696  0.5 32.45  ? 601 BYZ A N2  1 
HETATM 8976 C  C3  A BYZ E 3 .   ? -10.062 -21.708 23.82   0.5 36.01  ? 601 BYZ A C3  1 
HETATM 8977 C  C3  B BYZ E 3 .   ? -9.328  -21.121 23.16   0.5 34.38  ? 601 BYZ A C3  1 
HETATM 8978 BR BR4 . BYZ F 3 .   ? 13.428  -27.307 -10.611 1   79.54  ? 603 BYZ A BR4 1 
HETATM 8979 C  C4  . BYZ F 3 .   ? 13.794  -26.285 -9.078  1   62.67  ? 603 BYZ A C4  1 
HETATM 8980 C  C5  . BYZ F 3 .   ? 14.84   -26.479 -8.178  1   60.51  ? 603 BYZ A C5  1 
HETATM 8981 N  N1  . BYZ F 3 .   ? 14.771  -25.563 -7.243  1   62.37  ? 603 BYZ A N1  1 
HETATM 8982 N  N2  . BYZ F 3 .   ? 13.714  -24.779 -7.535  1   61.78  ? 603 BYZ A N2  1 
HETATM 8983 C  C3  . BYZ F 3 .   ? 13.093  -25.194 -8.635  1   58.95  ? 603 BYZ A C3  1 
HETATM 8984 BR BR4 . BYZ G 3 .   ? -7.133  -12.395 32.295  0.5 80.7   ? 604 BYZ A BR4 1 
HETATM 8985 C  C4  . BYZ G 3 .   ? -8.187  -11.212 33.287  0.5 64.46  ? 604 BYZ A C4  1 
HETATM 8986 C  C5  . BYZ G 3 .   ? -9.069  -11.577 34.299  0.5 63.78  ? 604 BYZ A C5  1 
HETATM 8987 N  N1  . BYZ G 3 .   ? -9.621  -10.494 34.798  0.5 64.83  ? 604 BYZ A N1  1 
HETATM 8988 N  N2  . BYZ G 3 .   ? -9.109  -9.46   34.102  0.5 65.81  ? 604 BYZ A N2  1 
HETATM 8989 C  C3  . BYZ G 3 .   ? -8.234  -9.86   33.179  0.5 62.61  ? 604 BYZ A C3  1 
HETATM 8990 BR BR4 . BYZ H 3 .   ? -5.774  -47.094 11.101  1   86.41  ? 605 BYZ A BR4 1 
HETATM 8991 C  C4  . BYZ H 3 .   ? -5.349  -46.336 12.773  1   84.29  ? 605 BYZ A C4  1 
HETATM 8992 C  C5  . BYZ H 3 .   ? -6.086  -46.445 13.958  1   79.04  ? 605 BYZ A C5  1 
HETATM 8993 N  N1  . BYZ H 3 .   ? -5.461  -45.793 14.924  1   78.5   ? 605 BYZ A N1  1 
HETATM 8994 N  N2  . BYZ H 3 .   ? -4.344  -45.25  14.387  1   81.77  ? 605 BYZ A N2  1 
HETATM 8995 C  C3  . BYZ H 3 .   ? -4.235  -45.553 13.087  1   79.07  ? 605 BYZ A C3  1 
HETATM 8996 BR BR4 . BYZ I 3 .   ? -19.213 -11.217 20.241  1   122.82 ? 606 BYZ A BR4 1 
HETATM 8997 C  C4  . BYZ I 3 .   ? -19.214 -9.34   20.12   1   109.86 ? 606 BYZ A C4  1 
HETATM 8998 C  C5  . BYZ I 3 .   ? -19.712 -8.433  21.059  1   105.97 ? 606 BYZ A C5  1 
HETATM 8999 N  N1  . BYZ I 3 .   ? -19.531 -7.192  20.604  1   107.5  ? 606 BYZ A N1  1 
HETATM 9000 N  N2  . BYZ I 3 .   ? -18.921 -7.293  19.402  1   96.37  ? 606 BYZ A N2  1 
HETATM 9001 C  C3  . BYZ I 3 .   ? -18.707 -8.575  19.076  1   98.06  ? 606 BYZ A C3  1 
HETATM 9002 BR BR4 . BYZ J 3 .   ? -6.613  -11.809 30.401  0.5 76.51  ? 607 BYZ A BR4 1 
HETATM 9003 C  C4  . BYZ J 3 .   ? -5.28   -12.013 29.115  0.5 67.73  ? 607 BYZ A C4  1 
HETATM 9004 C  C5  . BYZ J 3 .   ? -5.394  -12.741 27.941  0.5 63.33  ? 607 BYZ A C5  1 
HETATM 9005 N  N1  . BYZ J 3 .   ? -4.253  -12.644 27.287  0.5 67.02  ? 607 BYZ A N1  1 
HETATM 9006 N  N2  . BYZ J 3 .   ? -3.417  -11.878 28.028  0.5 70.56  ? 607 BYZ A N2  1 
HETATM 9007 C  C3  . BYZ J 3 .   ? -4.014  -11.481 29.154  0.5 71.03  ? 607 BYZ A C3  1 
HETATM 9008 BR BR4 . BYZ K 3 .   ? -18.181 15.057  3.873   1   88.59  ? 501 BYZ B BR4 1 
HETATM 9009 C  C4  . BYZ K 3 .   ? -18.926 16.776  3.696   1   78.65  ? 501 BYZ B C4  1 
HETATM 9010 C  C5  . BYZ K 3 .   ? -18.809 17.836  4.601   1   74.26  ? 501 BYZ B C5  1 
HETATM 9011 N  N1  . BYZ K 3 .   ? -19.487 18.869  4.151   1   72.83  ? 501 BYZ B N1  1 
HETATM 9012 N  N2  . BYZ K 3 .   ? -20.041 18.487  2.98    1   73.41  ? 501 BYZ B N2  1 
HETATM 9013 C  C3  . BYZ K 3 .   ? -19.727 17.228  2.671   1   68.29  ? 501 BYZ B C3  1 
HETATM 9014 BR BR4 . BYZ L 3 .   ? -15.594 14.897  1.548   1   94.93  ? 502 BYZ B BR4 1 
HETATM 9015 C  C4  . BYZ L 3 .   ? -15.195 16.682  1.971   1   109.71 ? 502 BYZ B C4  1 
HETATM 9016 C  C5  . BYZ L 3 .   ? -16.081 17.765  1.993   1   111.85 ? 502 BYZ B C5  1 
HETATM 9017 N  N1  . BYZ L 3 .   ? -15.405 18.855  2.365   1   114.4  ? 502 BYZ B N1  1 
HETATM 9018 N  N2  . BYZ L 3 .   ? -14.118 18.484  2.585   1   110.53 ? 502 BYZ B N2  1 
HETATM 9019 C  C3  . BYZ L 3 .   ? -13.95  17.172  2.361   1   110.97 ? 502 BYZ B C3  1 
HETATM 9020 BR BR4 A BYZ M 3 .   ? -32.989 17.118  31.091  0.5 83.68  ? 501 BYZ C BR4 1 
HETATM 9021 BR BR4 B BYZ M 3 .   ? -33.042 14.2    29.627  0.5 26.07  ? 501 BYZ C BR4 1 
HETATM 9022 C  C4  A BYZ M 3 .   ? -32.825 16.722  29.259  0.5 72.65  ? 501 BYZ C C4  1 
HETATM 9023 C  C4  B BYZ M 3 .   ? -32.781 15.842  28.764  0.5 27.86  ? 501 BYZ C C4  1 
HETATM 9024 C  C5  A BYZ M 3 .   ? -32.637 17.628  28.209  0.5 67.11  ? 501 BYZ C C5  1 
HETATM 9025 C  C5  B BYZ M 3 .   ? -32.781 17.105  29.356  0.5 28.9   ? 501 BYZ C C5  1 
HETATM 9026 N  N1  A BYZ M 3 .   ? -32.562 16.971  27.061  0.5 63.76  ? 501 BYZ C N1  1 
HETATM 9027 N  N1  B BYZ M 3 .   ? -32.567 18.039  28.434  0.5 28.91  ? 501 BYZ C N1  1 
HETATM 9028 N  N2  A BYZ M 3 .   ? -32.717 15.666  27.358  0.5 65.09  ? 501 BYZ C N2  1 
HETATM 9029 N  N2  B BYZ M 3 .   ? -32.422 17.393  27.277  0.5 28.65  ? 501 BYZ C N2  1 
HETATM 9030 C  C3  A BYZ M 3 .   ? -32.871 15.472  28.674  0.5 66.96  ? 501 BYZ C C3  1 
HETATM 9031 C  C3  B BYZ M 3 .   ? -32.564 16.072  27.43   0.5 28.23  ? 501 BYZ C C3  1 
HETATM 9032 BR BR4 . BYZ N 3 .   ? -69.78  19.209  44.46   1   92.26  ? 502 BYZ C BR4 1 
HETATM 9033 C  C4  . BYZ N 3 .   ? -68.966 20.376  45.681  1   90.72  ? 502 BYZ C C4  1 
HETATM 9034 C  C5  . BYZ N 3 .   ? -67.98  21.319  45.397  1   81.22  ? 502 BYZ C C5  1 
HETATM 9035 N  N1  . BYZ N 3 .   ? -67.667 21.935  46.527  1   82.06  ? 502 BYZ C N1  1 
HETATM 9036 N  N2  . BYZ N 3 .   ? -68.416 21.412  47.529  1   84.77  ? 502 BYZ C N2  1 
HETATM 9037 C  C3  . BYZ N 3 .   ? -69.222 20.457  47.055  1   87.7   ? 502 BYZ C C3  1 
HETATM 9038 BR BR4 . BYZ O 3 .   ? -21.161 13.813  32.541  1   93.37  ? 503 BYZ C BR4 1 
HETATM 9039 C  C4  . BYZ O 3 .   ? -19.545 13.101  31.897  1   81.61  ? 503 BYZ C C4  1 
HETATM 9040 C  C5  . BYZ O 3 .   ? -18.953 13.324  30.651  1   75.39  ? 503 BYZ C C5  1 
HETATM 9041 N  N1  . BYZ O 3 .   ? -17.829 12.62   30.566  1   76.3   ? 503 BYZ C N1  1 
HETATM 9042 N  N2  . BYZ O 3 .   ? -17.699 11.951  31.73   1   78.54  ? 503 BYZ C N2  1 
HETATM 9043 C  C3  . BYZ O 3 .   ? -18.713 12.219  32.561  1   76.42  ? 503 BYZ C C3  1 
HETATM 9044 BR BR4 . BYZ P 3 .   ? -32.831 -23.426 43.753  1   65.13  ? 501 BYZ D BR4 1 
HETATM 9045 C  C4  . BYZ P 3 .   ? -32.515 -24.162 45.443  1   64.98  ? 501 BYZ D C4  1 
HETATM 9046 C  C5  . BYZ P 3 .   ? -31.318 -24.711 45.899  1   67.54  ? 501 BYZ D C5  1 
HETATM 9047 N  N1  . BYZ P 3 .   ? -31.488 -25.11  47.145  1   79.39  ? 501 BYZ D N1  1 
HETATM 9048 N  N2  . BYZ P 3 .   ? -32.768 -24.816 47.487  1   77.53  ? 501 BYZ D N2  1 
HETATM 9049 C  C3  . BYZ P 3 .   ? -33.415 -24.239 46.472  1   69.67  ? 501 BYZ D C3  1 
HETATM 9050 BR BR4 . BYZ Q 3 .   ? -25.702 -1.367  35.299  1   122.01 ? 502 BYZ D BR4 1 
HETATM 9051 C  C4  . BYZ Q 3 .   ? -24.393 -2.709  35.277  1   87.4   ? 502 BYZ D C4  1 
HETATM 9052 C  C5  . BYZ Q 3 .   ? -23.025 -2.544  35.484  1   80.31  ? 502 BYZ D C5  1 
HETATM 9053 N  N1  . BYZ Q 3 .   ? -22.425 -3.716  35.397  1   74.54  ? 502 BYZ D N1  1 
HETATM 9054 N  N2  . BYZ Q 3 .   ? -23.396 -4.608  35.145  1   74.34  ? 502 BYZ D N2  1 
HETATM 9055 C  C3  . BYZ Q 3 .   ? -24.595 -4.034  35.07   1   71.47  ? 502 BYZ D C3  1 
HETATM 9056 O  O   . HOH R 4 .   ? 4.599   -19.324 -5.409  1   37.11  ? 701 HOH A O   1 
HETATM 9057 O  O   . HOH R 4 .   ? -21.473 -18.904 27.779  1   41.32  ? 702 HOH A O   1 
HETATM 9058 O  O   . HOH R 4 .   ? -16.609 -22.284 28.122  1   43.85  ? 703 HOH A O   1 
HETATM 9059 O  O   . HOH R 4 .   ? -10.232 -17.439 16.488  1   35.52  ? 704 HOH A O   1 
HETATM 9060 O  O   . HOH R 4 .   ? -13.57  -11.927 -3.493  1   39.23  ? 705 HOH A O   1 
HETATM 9061 O  O   . HOH R 4 .   ? -15.466 -31.121 27.768  1   51.65  ? 706 HOH A O   1 
HETATM 9062 O  O   . HOH R 4 .   ? -23.123 -10.237 7.839   1   47.52  ? 707 HOH A O   1 
HETATM 9063 O  O   . HOH R 4 .   ? 7.213   -19.543 -14.197 1   51.36  ? 708 HOH A O   1 
HETATM 9064 O  O   . HOH R 4 .   ? 11.586  -39.015 -13.617 1   39.13  ? 709 HOH A O   1 
HETATM 9065 O  O   . HOH R 4 .   ? -21.745 -35.058 13.967  1   38.62  ? 710 HOH A O   1 
HETATM 9066 O  O   . HOH R 4 .   ? -12.814 -28.741 -5.228  1   28.8   ? 711 HOH A O   1 
HETATM 9067 O  O   . HOH R 4 .   ? 15.858  -25.031 -5.115  1   39.16  ? 712 HOH A O   1 
HETATM 9068 O  O   . HOH R 4 .   ? -4.791  -8.992  7.902   1   51.44  ? 713 HOH A O   1 
HETATM 9069 O  O   . HOH R 4 .   ? -3.171  -12.259 5.727   1   34.37  ? 714 HOH A O   1 
HETATM 9070 O  O   . HOH R 4 .   ? -2.057  -24.296 8.607   1   40.83  ? 715 HOH A O   1 
HETATM 9071 O  O   . HOH R 4 .   ? -15.57  -37.574 19.492  1   40.69  ? 716 HOH A O   1 
HETATM 9072 O  O   . HOH R 4 .   ? -21.45  -17.669 31.578  1   31.68  ? 717 HOH A O   1 
HETATM 9073 O  O   . HOH R 4 .   ? 3.896   -20.912 -1.14   1   25.53  ? 718 HOH A O   1 
HETATM 9074 O  O   . HOH R 4 .   ? -13.636 -36.241 -5.307  1   50.73  ? 719 HOH A O   1 
HETATM 9075 O  O   . HOH R 4 .   ? 9.294   -31.449 -15.144 1   44.14  ? 720 HOH A O   1 
HETATM 9076 O  O   . HOH R 4 .   ? -10.478 -10.181 37.779  1   49.08  ? 721 HOH A O   1 
HETATM 9077 O  O   . HOH R 4 .   ? 0.161   -19.189 33.723  1   54.23  ? 722 HOH A O   1 
HETATM 9078 O  O   . HOH R 4 .   ? -3.478  -19.091 39.022  1   50.39  ? 723 HOH A O   1 
HETATM 9079 O  O   . HOH R 4 .   ? -4.937  -38.086 -4.67   1   37.1   ? 724 HOH A O   1 
HETATM 9080 O  O   . HOH R 4 .   ? -2.956  -42.655 15.231  1   41.24  ? 725 HOH A O   1 
HETATM 9081 O  O   . HOH R 4 .   ? -14.166 -46.45  -0.515  1   45.58  ? 726 HOH A O   1 
HETATM 9082 O  O   . HOH R 4 .   ? -5.367  -15.935 -4.897  1   33.23  ? 727 HOH A O   1 
HETATM 9083 O  O   . HOH R 4 .   ? -9.788  -28.952 -14.096 1   35.31  ? 728 HOH A O   1 
HETATM 9084 O  O   . HOH R 4 .   ? -8.03   -23.784 -4.397  1   30.38  ? 729 HOH A O   1 
HETATM 9085 O  O   . HOH R 4 .   ? -22.894 -15.586 17.856  1   47.93  ? 730 HOH A O   1 
HETATM 9086 O  O   . HOH R 4 .   ? -2.714  -20.032 -5.581  1   27.05  ? 731 HOH A O   1 
HETATM 9087 O  O   . HOH R 4 .   ? -0.618  -13.583 5.58    1   48.27  ? 732 HOH A O   1 
HETATM 9088 O  O   . HOH R 4 .   ? -3.775  -5.752  7.047   1   38.54  ? 733 HOH A O   1 
HETATM 9089 O  O   . HOH R 4 .   ? -25.048 -24.109 13.634  1   40.95  ? 734 HOH A O   1 
HETATM 9090 O  O   . HOH R 4 .   ? -19.131 -15.153 42.507  1   47.15  ? 735 HOH A O   1 
HETATM 9091 O  O   . HOH R 4 .   ? -15.178 -12.038 -5.605  1   42.58  ? 736 HOH A O   1 
HETATM 9092 O  O   . HOH R 4 .   ? -11.78  -16.753 -9.618  1   50.73  ? 737 HOH A O   1 
HETATM 9093 O  O   . HOH R 4 .   ? -7.991  -16.588 -4.248  1   26.33  ? 738 HOH A O   1 
HETATM 9094 O  O   . HOH R 4 .   ? -12.619 -34.396 22.03   1   32.23  ? 739 HOH A O   1 
HETATM 9095 O  O   . HOH R 4 .   ? -3.748  -25.408 2.117   1   30.81  ? 740 HOH A O   1 
HETATM 9096 O  O   . HOH R 4 .   ? -20.535 -32.279 15.34   1   39.32  ? 741 HOH A O   1 
HETATM 9097 O  O   . HOH R 4 .   ? -3.185  -36.538 -5.754  1   28.5   ? 742 HOH A O   1 
HETATM 9098 O  O   . HOH R 4 .   ? -8.01   -33.046 -13.396 1   37.39  ? 743 HOH A O   1 
HETATM 9099 O  O   . HOH R 4 .   ? -3.62   -48.012 2.84    1   42.54  ? 744 HOH A O   1 
HETATM 9100 O  O   . HOH R 4 .   ? -12.753 -10.237 2.492   1   32.44  ? 745 HOH A O   1 
HETATM 9101 O  O   . HOH R 4 .   ? -19.348 -21.318 16.773  1   37.38  ? 746 HOH A O   1 
HETATM 9102 O  O   . HOH R 4 .   ? -1.516  -15.357 -6.328  1   46.32  ? 747 HOH A O   1 
HETATM 9103 O  O   . HOH R 4 .   ? -15.175 -27.447 0.928   1   26.6   ? 748 HOH A O   1 
HETATM 9104 O  O   . HOH R 4 .   ? -1.28   -17.886 -3.746  1   45.18  ? 749 HOH A O   1 
HETATM 9105 O  O   . HOH R 4 .   ? 2.84    -18.698 0.51    1   49.08  ? 750 HOH A O   1 
HETATM 9106 O  O   . HOH R 4 .   ? -18.981 -24.411 19.268  1   25.92  ? 751 HOH A O   1 
HETATM 9107 O  O   . HOH R 4 .   ? -7.526  -27.493 -13.9   1   46.73  ? 752 HOH A O   1 
HETATM 9108 O  O   . HOH R 4 .   ? 2.064   -32.692 -18.99  1   44.17  ? 753 HOH A O   1 
HETATM 9109 O  O   . HOH R 4 .   ? -16.626 -38.771 -3.347  1   46.96  ? 754 HOH A O   1 
HETATM 9110 O  O   . HOH R 4 .   ? -21.757 -28.702 8.045   1   33.75  ? 755 HOH A O   1 
HETATM 9111 O  O   . HOH R 4 .   ? -14.253 -27.19  -1.632  1   28.89  ? 756 HOH A O   1 
HETATM 9112 O  O   . HOH R 4 .   ? -12.531 -12.68  -9.575  1   43.97  ? 757 HOH A O   1 
HETATM 9113 O  O   . HOH R 4 .   ? 4.627   -21.957 7.585   1   30.8   ? 758 HOH A O   1 
HETATM 9114 O  O   . HOH R 4 .   ? -7.534  -18.567 10.268  1   29.5   ? 759 HOH A O   1 
HETATM 9115 O  O   . HOH R 4 .   ? -4.619  -8.572  4.85    1   40.49  ? 760 HOH A O   1 
HETATM 9116 O  O   . HOH R 4 .   ? 1.126   -38.463 7.938   1   34.5   ? 761 HOH A O   1 
HETATM 9117 O  O   . HOH R 4 .   ? 1.828   -32.261 6.346   1   25.54  ? 762 HOH A O   1 
HETATM 9118 O  O   . HOH R 4 .   ? -6.179  -24.314 5.627   1   30.51  ? 763 HOH A O   1 
HETATM 9119 O  O   . HOH R 4 .   ? 14.44   -32.677 2.302   1   44.84  ? 764 HOH A O   1 
HETATM 9120 O  O   . HOH R 4 .   ? -23.322 -34.723 2.134   1   27.82  ? 765 HOH A O   1 
HETATM 9121 O  O   . HOH R 4 .   ? -6.895  -19.521 19.269  1   47.85  ? 766 HOH A O   1 
HETATM 9122 O  O   . HOH R 4 .   ? -12.406 -28.879 -2.408  1   27.14  ? 767 HOH A O   1 
HETATM 9123 O  O   . HOH R 4 .   ? 8.789   -23.266 -7.853  1   49.58  ? 768 HOH A O   1 
HETATM 9124 O  O   . HOH R 4 .   ? -2.504  -2.302  14.447  1   54.2   ? 769 HOH A O   1 
HETATM 9125 O  O   . HOH R 4 .   ? 1.132   -29.476 2.122   1   36.97  ? 770 HOH A O   1 
HETATM 9126 O  O   . HOH R 4 .   ? -2.836  -15.56  -3.941  1   39.23  ? 771 HOH A O   1 
HETATM 9127 O  O   . HOH R 4 .   ? -3.919  -36.01  26.533  1   47.6   ? 772 HOH A O   1 
HETATM 9128 O  O   . HOH R 4 .   ? 0.145   -33.489 8.072   1   26.92  ? 773 HOH A O   1 
HETATM 9129 O  O   . HOH R 4 .   ? -6.676  -52.193 2.715   1   52.58  ? 774 HOH A O   1 
HETATM 9130 O  O   . HOH R 4 .   ? -12.558 -49.689 4.048   1   47.92  ? 775 HOH A O   1 
HETATM 9131 O  O   . HOH R 4 .   ? -22.873 -26.902 4.78    1   39.12  ? 776 HOH A O   1 
HETATM 9132 O  O   . HOH R 4 .   ? 2.39    -30.331 13.3    1   50.43  ? 777 HOH A O   1 
HETATM 9133 O  O   . HOH R 4 .   ? 13.077  -24.497 -15.65  1   48.39  ? 778 HOH A O   1 
HETATM 9134 O  O   . HOH R 4 .   ? -1.629  -8.01   20.563  1   52.56  ? 779 HOH A O   1 
HETATM 9135 O  O   . HOH R 4 .   ? -19.418 -32.629 18.534  1   36.21  ? 780 HOH A O   1 
HETATM 9136 O  O   . HOH R 4 .   ? -14.238 -4.434  33.826  1   53.15  ? 781 HOH A O   1 
HETATM 9137 O  O   . HOH R 4 .   ? -22.255 -43.403 1.553   1   51.78  ? 782 HOH A O   1 
HETATM 9138 O  O   . HOH R 4 .   ? -23.132 -47.905 10.723  1   53.43  ? 783 HOH A O   1 
HETATM 9139 O  O   . HOH R 4 .   ? -10.648 -11.261 -10.083 1   44.98  ? 784 HOH A O   1 
HETATM 9140 O  O   . HOH R 4 .   ? -12.127 -43.525 -4.63   1   42.02  ? 785 HOH A O   1 
HETATM 9141 O  O   . HOH R 4 .   ? -12.995 -47.713 8.218   1   47.49  ? 786 HOH A O   1 
HETATM 9142 O  O   . HOH R 4 .   ? -12.406 -10.918 5.235   1   32.23  ? 787 HOH A O   1 
HETATM 9143 O  O   . HOH R 4 .   ? -6.401  -25.647 -11.569 1   42.23  ? 788 HOH A O   1 
HETATM 9144 O  O   . HOH R 4 .   ? 15.206  -26.761 1.369   1   44.15  ? 789 HOH A O   1 
HETATM 9145 O  O   . HOH R 4 .   ? -25.348 -21.164 4.132   1   50.59  ? 790 HOH A O   1 
HETATM 9146 O  O   . HOH R 4 .   ? 0.492   -37.604 -10.22  1   38.54  ? 791 HOH A O   1 
HETATM 9147 O  O   . HOH R 4 .   ? -23.834 -28.901 10.44   1   39.01  ? 792 HOH A O   1 
HETATM 9148 O  O   . HOH R 4 .   ? -14.823 -46.714 13.066  1   43.43  ? 793 HOH A O   1 
HETATM 9149 O  O   . HOH R 4 .   ? -19.102 -31.056 23.296  1   39.32  ? 794 HOH A O   1 
HETATM 9150 O  O   . HOH R 4 .   ? -8.045  -12.167 37.524  1   53.88  ? 795 HOH A O   1 
HETATM 9151 O  O   . HOH R 4 .   ? -16.426 -43.663 14.724  1   52.66  ? 796 HOH A O   1 
HETATM 9152 O  O   . HOH R 4 .   ? -6.291  -24.935 25.701  1   42.51  ? 797 HOH A O   1 
HETATM 9153 O  O   . HOH R 4 .   ? -19.695 -23.43  28.463  1   45.61  ? 798 HOH A O   1 
HETATM 9154 O  O   . HOH R 4 .   ? -19.645 -30.124 19.48   1   47.55  ? 799 HOH A O   1 
HETATM 9155 O  O   . HOH R 4 .   ? -9.468  -46.723 -2.256  1   45.45  ? 800 HOH A O   1 
HETATM 9156 O  O   . HOH R 4 .   ? -5.389  -25.523 28.343  1   43.78  ? 801 HOH A O   1 
HETATM 9157 O  O   . HOH R 4 .   ? 11.019  -21.081 1.098   1   51.84  ? 802 HOH A O   1 
HETATM 9158 O  O   . HOH R 4 .   ? 12.001  -22.515 -1.55   1   45.1   ? 803 HOH A O   1 
HETATM 9159 O  O   . HOH R 4 .   ? -16.829 -32.588 -4.332  1   39.6   ? 804 HOH A O   1 
HETATM 9160 O  O   . HOH R 4 .   ? -15.297 -22.847 37.24   1   45.06  ? 805 HOH A O   1 
HETATM 9161 O  O   . HOH R 4 .   ? -9.392  -19.344 18.702  1   33.49  ? 806 HOH A O   1 
HETATM 9162 O  O   . HOH R 4 .   ? -5.017  -19.46  -10.854 1   37.4   ? 807 HOH A O   1 
HETATM 9163 O  O   . HOH R 4 .   ? -15.98  -24.804 28.627  1   52.37  ? 808 HOH A O   1 
HETATM 9164 O  O   . HOH R 4 .   ? -8.285  -10.584 -8.61   1   40.74  ? 809 HOH A O   1 
HETATM 9165 O  O   . HOH R 4 .   ? 3.812   -40.932 3.465   1   41.76  ? 810 HOH A O   1 
HETATM 9166 O  O   . HOH R 4 .   ? -20.583 -36.798 24.743  1   57.94  ? 811 HOH A O   1 
HETATM 9167 O  O   . HOH R 4 .   ? 6.803   -19.97  2.892   1   45.11  ? 812 HOH A O   1 
HETATM 9168 O  O   . HOH R 4 .   ? -4.365  -36.151 -8.486  1   32.89  ? 813 HOH A O   1 
HETATM 9169 O  O   . HOH R 4 .   ? -14.934 -12.086 -8.974  1   44.02  ? 814 HOH A O   1 
HETATM 9170 O  O   . HOH R 4 .   ? -14.977 -32.448 -6.893  1   52.51  ? 815 HOH A O   1 
HETATM 9171 O  O   . HOH R 4 .   ? -1.548  -23.324 23.522  1   52.99  ? 816 HOH A O   1 
HETATM 9172 O  O   . HOH R 4 .   ? -16.674 -46.214 14.636  1   37.05  ? 817 HOH A O   1 
HETATM 9173 O  O   . HOH R 4 .   ? -19.167 -10.259 32.626  1   43.46  ? 818 HOH A O   1 
HETATM 9174 O  O   . HOH R 4 .   ? 1.459   -23.668 15.774  1   38.77  ? 819 HOH A O   1 
HETATM 9175 O  O   . HOH R 4 .   ? 2.886   -24.841 13.792  1   45.77  ? 820 HOH A O   1 
HETATM 9176 O  O   . HOH R 4 .   ? -16.346 -41.997 -2.692  1   45.21  ? 821 HOH A O   1 
HETATM 9177 O  O   . HOH R 4 .   ? -18.4   -15.926 30.588  1   36.07  ? 822 HOH A O   1 
HETATM 9178 O  O   . HOH R 4 .   ? -15.833 -44.497 -2.167  1   50.89  ? 823 HOH A O   1 
HETATM 9179 O  O   . HOH R 4 .   ? 0.68    -27.564 20.257  1   46.76  ? 824 HOH A O   1 
HETATM 9180 O  O   . HOH R 4 .   ? -17.952 -23.901 31.278  1   38.25  ? 825 HOH A O   1 
HETATM 9181 O  O   . HOH R 4 .   ? -10.873 -47.732 6.178   1   37.12  ? 826 HOH A O   1 
HETATM 9182 O  O   . HOH R 4 .   ? -23.172 -25.268 18.926  1   60.47  ? 827 HOH A O   1 
HETATM 9183 O  O   . HOH R 4 .   ? 5.086   -26.054 9.04    1   50.67  ? 828 HOH A O   1 
HETATM 9184 O  O   . HOH R 4 .   ? -2.262  -8.333  8.205   1   38.9   ? 829 HOH A O   1 
HETATM 9185 O  O   . HOH R 4 .   ? -2.763  -19.354 -12.28  1   27.47  ? 830 HOH A O   1 
HETATM 9186 O  O   . HOH R 4 .   ? -14.469 -3.955  31.189  1   51.75  ? 831 HOH A O   1 
HETATM 9187 O  O   . HOH R 4 .   ? -24.191 -24.879 6.394   1   49.02  ? 832 HOH A O   1 
HETATM 9188 O  O   . HOH R 4 .   ? -6.881  -44.785 -3.269  1   33.94  ? 833 HOH A O   1 
HETATM 9189 O  O   . HOH R 4 .   ? -22.98  -27.407 20.797  1   48.86  ? 834 HOH A O   1 
HETATM 9190 O  O   . HOH R 4 .   ? -21.582 -45.624 3.574   1   54.46  ? 835 HOH A O   1 
HETATM 9191 O  O   . HOH R 4 .   ? -5.186  -43.24  -5.586  1   49.68  ? 836 HOH A O   1 
HETATM 9192 O  O   . HOH R 4 .   ? -2.279  -9.779  5.978   1   43.89  ? 837 HOH A O   1 
HETATM 9193 O  O   . HOH R 4 .   ? -1.657  -3.652  17.013  1   39.13  ? 838 HOH A O   1 
HETATM 9194 O  O   . HOH R 4 .   ? 3.751   -26.682 11.98   1   37.53  ? 839 HOH A O   1 
HETATM 9195 O  O   . HOH R 4 .   ? -4.623  -24.969 23.547  1   44.44  ? 840 HOH A O   1 
HETATM 9196 O  O   . HOH R 4 .   ? 15.874  -22.651 1.6     1   54.48  ? 841 HOH A O   1 
HETATM 9197 O  O   . HOH R 4 .   ? 6.824   -24.293 8.901   1   54.16  ? 842 HOH A O   1 
HETATM 9198 O  O   . HOH R 4 .   ? -9.711  -28.836 -17.267 1   49.35  ? 843 HOH A O   1 
HETATM 9199 O  O   . HOH S 4 .   ? -9.807  4.462   -13.121 1   50.02  ? 601 HOH B O   1 
HETATM 9200 O  O   . HOH S 4 .   ? -32.479 -10.405 0.549   1   36.35  ? 602 HOH B O   1 
HETATM 9201 O  O   . HOH S 4 .   ? -22.215 4.381   -20.308 1   44.92  ? 603 HOH B O   1 
HETATM 9202 O  O   . HOH S 4 .   ? -27.781 12.206  -3.889  1   43.96  ? 604 HOH B O   1 
HETATM 9203 O  O   . HOH S 4 .   ? -5.993  -6.399  5.285   1   37.17  ? 605 HOH B O   1 
HETATM 9204 O  O   . HOH S 4 .   ? -35.06  -3.346  -20.861 1   52.64  ? 606 HOH B O   1 
HETATM 9205 O  O   . HOH S 4 .   ? -29.513 9.075   -9.182  1   39.21  ? 607 HOH B O   1 
HETATM 9206 O  O   . HOH S 4 .   ? -8.465  2.199   16.494  1   41.2   ? 608 HOH B O   1 
HETATM 9207 O  O   . HOH S 4 .   ? -39.126 3.491   -9.622  1   49.53  ? 609 HOH B O   1 
HETATM 9208 O  O   . HOH S 4 .   ? -9.891  7.313   -11.268 1   38.95  ? 610 HOH B O   1 
HETATM 9209 O  O   . HOH S 4 .   ? -12.563 9.018   -10.1   1   48.37  ? 611 HOH B O   1 
HETATM 9210 O  O   . HOH S 4 .   ? -25.342 -26.239 3.679   1   36.63  ? 612 HOH B O   1 
HETATM 9211 O  O   . HOH S 4 .   ? -32.346 8.768   4.826   1   51.98  ? 613 HOH B O   1 
HETATM 9212 O  O   . HOH S 4 .   ? -31.136 0.938   3.606   1   51.48  ? 614 HOH B O   1 
HETATM 9213 O  O   . HOH S 4 .   ? -26.486 10.465  -1.094  1   49.61  ? 615 HOH B O   1 
HETATM 9214 O  O   . HOH S 4 .   ? -26.418 -19.526 -10.08  1   45.72  ? 616 HOH B O   1 
HETATM 9215 O  O   . HOH S 4 .   ? -28.17  -4.334  3.08    1   42     ? 617 HOH B O   1 
HETATM 9216 O  O   . HOH S 4 .   ? -16.416 -8.477  1.425   1   25.26  ? 618 HOH B O   1 
HETATM 9217 O  O   . HOH S 4 .   ? -18.913 20.467  6.11    1   51.75  ? 619 HOH B O   1 
HETATM 9218 O  O   . HOH S 4 .   ? -16.823 14.736  -3.415  1   40.77  ? 620 HOH B O   1 
HETATM 9219 O  O   . HOH S 4 .   ? -3.651  -0.293  -2.107  1   51.02  ? 621 HOH B O   1 
HETATM 9220 O  O   . HOH S 4 .   ? -36.904 -13.995 -4.164  1   41.96  ? 622 HOH B O   1 
HETATM 9221 O  O   . HOH S 4 .   ? -4.63   -4.461  -1.227  1   50.18  ? 623 HOH B O   1 
HETATM 9222 O  O   . HOH S 4 .   ? -13.941 -10.883 -0.726  1   40.29  ? 624 HOH B O   1 
HETATM 9223 O  O   . HOH S 4 .   ? -18.709 -1.233  -8.298  1   51.63  ? 625 HOH B O   1 
HETATM 9224 O  O   . HOH S 4 .   ? -37.946 5.779   -6.376  1   45.84  ? 626 HOH B O   1 
HETATM 9225 O  O   . HOH S 4 .   ? -31.715 -18.428 -18.705 1   40.71  ? 627 HOH B O   1 
HETATM 9226 O  O   . HOH S 4 .   ? -24.218 -20.139 -18.147 1   59.47  ? 628 HOH B O   1 
HETATM 9227 O  O   . HOH S 4 .   ? -17.053 -8.39   -4.203  1   36.54  ? 629 HOH B O   1 
HETATM 9228 O  O   . HOH S 4 .   ? -37.473 -3.342  -7.874  1   46.78  ? 630 HOH B O   1 
HETATM 9229 O  O   . HOH S 4 .   ? -6.61   -3.347  -4.163  1   39.19  ? 631 HOH B O   1 
HETATM 9230 O  O   . HOH S 4 .   ? -29.172 0.567   -1.196  1   46.12  ? 632 HOH B O   1 
HETATM 9231 O  O   . HOH S 4 .   ? -24.525 8.251   -18.824 1   45.55  ? 633 HOH B O   1 
HETATM 9232 O  O   . HOH S 4 .   ? -26.966 15.448  11.337  1   53.9   ? 634 HOH B O   1 
HETATM 9233 O  O   . HOH S 4 .   ? -22.533 10.994  -12.58  1   44.61  ? 635 HOH B O   1 
HETATM 9234 O  O   . HOH S 4 .   ? -20.407 -13.567 -3.994  1   34.19  ? 636 HOH B O   1 
HETATM 9235 O  O   . HOH S 4 .   ? -23.292 -2.462  -2.154  1   40.12  ? 637 HOH B O   1 
HETATM 9236 O  O   . HOH S 4 .   ? -18.243 -12.953 -12.21  1   41.54  ? 638 HOH B O   1 
HETATM 9237 O  O   . HOH S 4 .   ? -28.807 -23.311 -0.42   1   46.05  ? 639 HOH B O   1 
HETATM 9238 O  O   . HOH S 4 .   ? -17.648 -10.925 -5.344  1   50.38  ? 640 HOH B O   1 
HETATM 9239 O  O   . HOH S 4 .   ? -21.119 17.978  -13.037 1   48.93  ? 641 HOH B O   1 
HETATM 9240 O  O   . HOH S 4 .   ? -19.758 10.06   -8.664  1   43.94  ? 642 HOH B O   1 
HETATM 9241 O  O   . HOH S 4 .   ? -35.398 -12.882 0.449   1   44.39  ? 643 HOH B O   1 
HETATM 9242 O  O   . HOH S 4 .   ? -27.222 10.691  -12.436 1   53.22  ? 644 HOH B O   1 
HETATM 9243 O  O   . HOH S 4 .   ? -28.004 5.98    19.047  1   50.16  ? 645 HOH B O   1 
HETATM 9244 O  O   . HOH S 4 .   ? -12.019 -3.327  -7.93   1   41.42  ? 646 HOH B O   1 
HETATM 9245 O  O   . HOH S 4 .   ? -27.276 4.8     -1.947  1   55.93  ? 647 HOH B O   1 
HETATM 9246 O  O   . HOH S 4 .   ? -24.91  -24.684 -1.804  1   28.94  ? 648 HOH B O   1 
HETATM 9247 O  O   . HOH S 4 .   ? -8.326  -22.961 -7.081  1   39.77  ? 649 HOH B O   1 
HETATM 9248 O  O   . HOH S 4 .   ? -19.872 9.835   -11.677 1   47.33  ? 650 HOH B O   1 
HETATM 9249 O  O   . HOH S 4 .   ? -22.891 2.944   -26.499 1   49.39  ? 651 HOH B O   1 
HETATM 9250 O  O   . HOH S 4 .   ? -24.214 -24.545 -4.431  1   37.08  ? 652 HOH B O   1 
HETATM 9251 O  O   . HOH S 4 .   ? -6.38   14.932  18.355  1   50     ? 653 HOH B O   1 
HETATM 9252 O  O   . HOH S 4 .   ? -32.288 9.619   2.203   1   64.65  ? 654 HOH B O   1 
HETATM 9253 O  O   . HOH S 4 .   ? -30.071 18.148  7.697   1   61.28  ? 655 HOH B O   1 
HETATM 9254 O  O   . HOH S 4 .   ? -38.531 -11.525 -15.93  1   46.43  ? 656 HOH B O   1 
HETATM 9255 O  O   . HOH S 4 .   ? -24.951 -14.916 10.909  1   47.22  ? 657 HOH B O   1 
HETATM 9256 O  O   . HOH S 4 .   ? -24.077 -18.169 -9.174  1   62.2   ? 658 HOH B O   1 
HETATM 9257 O  O   . HOH S 4 .   ? -31.198 15.573  2.447   1   46.45  ? 659 HOH B O   1 
HETATM 9258 O  O   . HOH S 4 .   ? -19.761 -9.376  10.36   1   35.11  ? 660 HOH B O   1 
HETATM 9259 O  O   . HOH S 4 .   ? -6.405  -1.785  -18.822 1   42.4   ? 661 HOH B O   1 
HETATM 9260 O  O   . HOH S 4 .   ? -21.815 7.851   -18.157 1   39.14  ? 662 HOH B O   1 
HETATM 9261 O  O   . HOH S 4 .   ? -18.42  -8.715  3.402   1   28.59  ? 663 HOH B O   1 
HETATM 9262 O  O   . HOH S 4 .   ? -33.434 -6.169  -27.93  1   52.94  ? 664 HOH B O   1 
HETATM 9263 O  O   . HOH S 4 .   ? -19.804 20.775  11.984  1   53.97  ? 665 HOH B O   1 
HETATM 9264 O  O   . HOH S 4 .   ? -37.881 -15.564 -18.113 1   46.91  ? 666 HOH B O   1 
HETATM 9265 O  O   . HOH S 4 .   ? -19.726 -13.375 -0.984  1   41.33  ? 667 HOH B O   1 
HETATM 9266 O  O   . HOH S 4 .   ? -23.352 -27.927 -7.507  1   58.42  ? 668 HOH B O   1 
HETATM 9267 O  O   . HOH S 4 .   ? -30.114 -2.301  -26.764 1   56.79  ? 669 HOH B O   1 
HETATM 9268 O  O   . HOH S 4 .   ? -13.948 -5.754  -5.724  1   31.87  ? 670 HOH B O   1 
HETATM 9269 O  O   . HOH S 4 .   ? -13.828 -21.825 -12.349 1   40.3   ? 671 HOH B O   1 
HETATM 9270 O  O   . HOH S 4 .   ? -30.761 8.607   12.593  1   46.27  ? 672 HOH B O   1 
HETATM 9271 O  O   . HOH S 4 .   ? -30.13  11.452  -2.805  1   41.02  ? 673 HOH B O   1 
HETATM 9272 O  O   . HOH S 4 .   ? -30.599 -12.55  -5.355  1   34.14  ? 674 HOH B O   1 
HETATM 9273 O  O   . HOH S 4 .   ? -30.152 10.89   13.566  1   46.02  ? 675 HOH B O   1 
HETATM 9274 O  O   . HOH S 4 .   ? -3.702  20.411  10.647  1   60.03  ? 676 HOH B O   1 
HETATM 9275 O  O   . HOH S 4 .   ? -14.762 17.7    6.18    1   48.47  ? 677 HOH B O   1 
HETATM 9276 O  O   . HOH S 4 .   ? -22.487 10.448  -9.184  1   41.13  ? 678 HOH B O   1 
HETATM 9277 O  O   . HOH S 4 .   ? -34.247 7.296   0.594   1   57.22  ? 679 HOH B O   1 
HETATM 9278 O  O   . HOH S 4 .   ? -24.44  -3.029  1.36    1   53.83  ? 680 HOH B O   1 
HETATM 9279 O  O   . HOH S 4 .   ? -1.611  -9.572  3.433   1   55.04  ? 681 HOH B O   1 
HETATM 9280 O  O   . HOH S 4 .   ? -25.239 -2.861  12.246  1   55.88  ? 682 HOH B O   1 
HETATM 9281 O  O   . HOH S 4 .   ? -27.271 -25.904 -1.86   1   42.38  ? 683 HOH B O   1 
HETATM 9282 O  O   . HOH S 4 .   ? -25.154 8.817   -9.249  1   50.52  ? 684 HOH B O   1 
HETATM 9283 O  O   . HOH S 4 .   ? -35.772 -8.817  -2.073  1   38.48  ? 685 HOH B O   1 
HETATM 9284 O  O   . HOH S 4 .   ? -7.096  -21.044 -10.602 1   37.24  ? 686 HOH B O   1 
HETATM 9285 O  O   . HOH S 4 .   ? -31.701 3.026   -27.189 1   54.15  ? 687 HOH B O   1 
HETATM 9286 O  O   . HOH S 4 .   ? -30.678 6.595   16.89   1   68.36  ? 688 HOH B O   1 
HETATM 9287 O  O   . HOH S 4 .   ? -4.195  -2.838  -6.455  1   56.84  ? 689 HOH B O   1 
HETATM 9288 O  O   . HOH S 4 .   ? -28.553 -17.589 -19.258 1   53.82  ? 690 HOH B O   1 
HETATM 9289 O  O   . HOH S 4 .   ? -6.65   -6.528  -2.446  1   44.91  ? 691 HOH B O   1 
HETATM 9290 O  O   . HOH S 4 .   ? -17.996 -13.961 -15.067 1   42.98  ? 692 HOH B O   1 
HETATM 9291 O  O   . HOH S 4 .   ? -30.218 -21.062 -11.579 1   47.84  ? 693 HOH B O   1 
HETATM 9292 O  O   . HOH S 4 .   ? -35.271 -4.216  -2.37   1   44.78  ? 694 HOH B O   1 
HETATM 9293 O  O   . HOH S 4 .   ? -12.085 -22.783 -11.071 1   37.25  ? 695 HOH B O   1 
HETATM 9294 O  O   . HOH S 4 .   ? -15.686 -10.42  -23.134 1   46.87  ? 696 HOH B O   1 
HETATM 9295 O  O   . HOH S 4 .   ? -26.768 15.645  -8.702  1   57.22  ? 697 HOH B O   1 
HETATM 9296 O  O   . HOH S 4 .   ? -11.419 -20.03  -12.839 1   39.75  ? 698 HOH B O   1 
HETATM 9297 O  O   . HOH S 4 .   ? -33.142 8.238   -10.165 1   44.51  ? 699 HOH B O   1 
HETATM 9298 O  O   . HOH S 4 .   ? -14.156 19.303  12.621  1   51.8   ? 700 HOH B O   1 
HETATM 9299 O  O   . HOH S 4 .   ? -19.036 -15.974 -16.565 1   45.15  ? 701 HOH B O   1 
HETATM 9300 O  O   . HOH S 4 .   ? -12.255 18.171  13.991  1   48.56  ? 702 HOH B O   1 
HETATM 9301 O  O   . HOH S 4 .   ? -29.502 0.65    1.179   1   56.39  ? 703 HOH B O   1 
HETATM 9302 O  O   . HOH S 4 .   ? -25.33  -0.635  1.69    1   48.63  ? 704 HOH B O   1 
HETATM 9303 O  O   . HOH S 4 .   ? -39.096 -11.627 -5.22   1   50.31  ? 705 HOH B O   1 
HETATM 9304 O  O   . HOH S 4 .   ? -27.403 -13.262 -19.46  1   46.6   ? 706 HOH B O   1 
HETATM 9305 O  O   . HOH S 4 .   ? -32.199 10.727  -11.77  1   52.14  ? 707 HOH B O   1 
HETATM 9306 O  O   . HOH S 4 .   ? -26.709 1.694   -2.708  1   49.99  ? 708 HOH B O   1 
HETATM 9307 O  O   . HOH S 4 .   ? -16.46  -10.308 -0.747  1   46.4   ? 709 HOH B O   1 
HETATM 9308 O  O   . HOH S 4 .   ? -24.285 -9.133  10.389  1   51.34  ? 710 HOH B O   1 
HETATM 9309 O  O   . HOH S 4 .   ? -23.94  8.897   -21.598 1   47.14  ? 711 HOH B O   1 
HETATM 9310 O  O   . HOH S 4 .   ? -27.602 -2.037  2.072   1   53.18  ? 712 HOH B O   1 
HETATM 9311 O  O   . HOH S 4 .   ? -12.798 16.408  -2.711  1   54.46  ? 713 HOH B O   1 
HETATM 9312 O  O   . HOH S 4 .   ? -24.714 9.947   -11.464 1   40.71  ? 714 HOH B O   1 
HETATM 9313 O  O   . HOH S 4 .   ? -16.254 -11.467 -11.053 1   33.78  ? 715 HOH B O   1 
HETATM 9314 O  O   . HOH S 4 .   ? -25.198 -0.483  -1.724  1   47.91  ? 716 HOH B O   1 
HETATM 9315 O  O   . HOH S 4 .   ? -14.782 18.905  -5.337  1   59.43  ? 717 HOH B O   1 
HETATM 9316 O  O   . HOH T 4 .   ? -46.227 15.188  37.907  1   47.35  ? 601 HOH C O   1 
HETATM 9317 O  O   . HOH T 4 .   ? -45.562 24.104  37.76   1   47.74  ? 602 HOH C O   1 
HETATM 9318 O  O   . HOH T 4 .   ? -28.961 15.13   20.635  1   52.9   ? 603 HOH C O   1 
HETATM 9319 O  O   . HOH T 4 .   ? -43.606 32.926  23.982  1   59.79  ? 604 HOH C O   1 
HETATM 9320 O  O   . HOH T 4 .   ? -63.084 29.658  45.494  1   51.99  ? 605 HOH C O   1 
HETATM 9321 O  O   . HOH T 4 .   ? -41.983 0.391   42.888  1   52.4   ? 606 HOH C O   1 
HETATM 9322 O  O   . HOH T 4 .   ? -27.891 10.108  17.736  1   46.88  ? 607 HOH C O   1 
HETATM 9323 O  O   . HOH T 4 .   ? -43.531 6.806   44.135  1   44.52  ? 608 HOH C O   1 
HETATM 9324 O  O   . HOH T 4 .   ? -45.003 23.751  17.173  1   58.29  ? 609 HOH C O   1 
HETATM 9325 O  O   . HOH T 4 .   ? -37.503 30.246  26.437  1   46.6   ? 610 HOH C O   1 
HETATM 9326 O  O   . HOH T 4 .   ? -23.905 0.588   47.988  1   35.62  ? 611 HOH C O   1 
HETATM 9327 O  O   . HOH T 4 .   ? -37.266 30.686  31.801  1   48.1   ? 612 HOH C O   1 
HETATM 9328 O  O   . HOH T 4 .   ? -37.968 28.625  34.809  1   41.93  ? 613 HOH C O   1 
HETATM 9329 O  O   . HOH T 4 .   ? -53.831 1.311   40.064  1   51.09  ? 614 HOH C O   1 
HETATM 9330 O  O   . HOH T 4 .   ? -28.093 24.654  26.041  1   52.59  ? 615 HOH C O   1 
HETATM 9331 O  O   . HOH T 4 .   ? -35.134 0.483   43.645  1   39.79  ? 616 HOH C O   1 
HETATM 9332 O  O   . HOH T 4 .   ? -40.581 23.573  20.478  1   39.47  ? 617 HOH C O   1 
HETATM 9333 O  O   . HOH T 4 .   ? -40.383 29.501  38.065  1   47.19  ? 618 HOH C O   1 
HETATM 9334 O  O   . HOH T 4 .   ? -65.298 13.767  28.887  1   51.45  ? 619 HOH C O   1 
HETATM 9335 O  O   . HOH T 4 .   ? -23.258 10.604  17.431  1   37.95  ? 620 HOH C O   1 
HETATM 9336 O  O   . HOH T 4 .   ? -30.413 17.477  19.908  1   52.27  ? 621 HOH C O   1 
HETATM 9337 O  O   . HOH T 4 .   ? -38.014 11.573  19.761  1   46.94  ? 622 HOH C O   1 
HETATM 9338 O  O   . HOH T 4 .   ? -37.015 6.856   23.738  1   47.17  ? 623 HOH C O   1 
HETATM 9339 O  O   . HOH T 4 .   ? -70.333 11.901  50.112  1   48.31  ? 624 HOH C O   1 
HETATM 9340 O  O   . HOH T 4 .   ? -52.74  12.852  37.763  1   39     ? 625 HOH C O   1 
HETATM 9341 O  O   . HOH T 4 .   ? -52.964 -6.203  35.911  1   53.62  ? 626 HOH C O   1 
HETATM 9342 O  O   . HOH T 4 .   ? -42.718 37.255  28.791  1   46.49  ? 627 HOH C O   1 
HETATM 9343 O  O   . HOH T 4 .   ? -51.122 17.246  52.385  1   45.34  ? 628 HOH C O   1 
HETATM 9344 O  O   . HOH T 4 .   ? -41.131 4.121   37.895  1   36.68  ? 629 HOH C O   1 
HETATM 9345 O  O   . HOH T 4 .   ? -47.806 20.164  15.832  1   52.27  ? 630 HOH C O   1 
HETATM 9346 O  O   . HOH T 4 .   ? -42.444 9.086   34.918  1   30.36  ? 631 HOH C O   1 
HETATM 9347 O  O   . HOH T 4 .   ? -50.151 31.764  26.9    1   45.51  ? 632 HOH C O   1 
HETATM 9348 O  O   . HOH T 4 .   ? -53.927 23.665  53.239  1   48.32  ? 633 HOH C O   1 
HETATM 9349 O  O   . HOH T 4 .   ? -38.497 -3.843  27.982  1   51.07  ? 634 HOH C O   1 
HETATM 9350 O  O   . HOH T 4 .   ? -16.61  1.991   37.541  1   39.53  ? 635 HOH C O   1 
HETATM 9351 O  O   . HOH T 4 .   ? -56.958 26.803  42.322  1   34.17  ? 636 HOH C O   1 
HETATM 9352 O  O   . HOH T 4 .   ? -52.718 25.83   52.704  1   57.02  ? 637 HOH C O   1 
HETATM 9353 O  O   . HOH T 4 .   ? -23.347 10.586  20.886  1   38.64  ? 638 HOH C O   1 
HETATM 9354 O  O   . HOH T 4 .   ? -52.211 12.21   47.097  1   49.12  ? 639 HOH C O   1 
HETATM 9355 O  O   . HOH T 4 .   ? -49.884 10.471  46.137  1   41.75  ? 640 HOH C O   1 
HETATM 9356 O  O   . HOH T 4 .   ? -57.68  6.741   37.188  1   56.65  ? 641 HOH C O   1 
HETATM 9357 O  O   . HOH T 4 .   ? -52.195 22.414  38.247  1   34.19  ? 642 HOH C O   1 
HETATM 9358 O  O   . HOH T 4 .   ? -54.38  18.392  40.13   1   39.64  ? 643 HOH C O   1 
HETATM 9359 O  O   . HOH T 4 .   ? -21.638 0.064   28.492  1   42.15  ? 644 HOH C O   1 
HETATM 9360 O  O   . HOH T 4 .   ? -40.198 10.89   36.857  1   44.72  ? 645 HOH C O   1 
HETATM 9361 O  O   . HOH T 4 .   ? -51.317 23.577  35.719  1   40.33  ? 646 HOH C O   1 
HETATM 9362 O  O   . HOH T 4 .   ? -53.967 27.52   34.532  1   49.1   ? 647 HOH C O   1 
HETATM 9363 O  O   . HOH T 4 .   ? -48.905 12.34   34.754  1   33.46  ? 648 HOH C O   1 
HETATM 9364 O  O   . HOH T 4 .   ? -41.188 -6.078  25.474  1   44.47  ? 649 HOH C O   1 
HETATM 9365 O  O   . HOH T 4 .   ? -57.154 7.086   29.022  1   51.93  ? 650 HOH C O   1 
HETATM 9366 O  O   . HOH T 4 .   ? -47.608 -4.738  32.546  1   58.46  ? 651 HOH C O   1 
HETATM 9367 O  O   . HOH T 4 .   ? -16.353 -0.799  34.43   1   50.7   ? 652 HOH C O   1 
HETATM 9368 O  O   . HOH T 4 .   ? -38.981 15.106  37.841  1   55.11  ? 653 HOH C O   1 
HETATM 9369 O  O   . HOH T 4 .   ? -45.688 16.653  44.687  1   55.21  ? 654 HOH C O   1 
HETATM 9370 O  O   . HOH T 4 .   ? -27.084 2.366   21.577  1   47.65  ? 655 HOH C O   1 
HETATM 9371 O  O   . HOH T 4 .   ? -48.284 9.934   16.368  1   50.02  ? 656 HOH C O   1 
HETATM 9372 O  O   . HOH T 4 .   ? -38.583 7.843   21.592  1   54.59  ? 657 HOH C O   1 
HETATM 9373 O  O   . HOH T 4 .   ? -32.635 20.962  28.692  1   45.99  ? 658 HOH C O   1 
HETATM 9374 O  O   . HOH T 4 .   ? -58.748 9.187   30.275  1   49.35  ? 659 HOH C O   1 
HETATM 9375 O  O   . HOH T 4 .   ? -14.854 17.911  18.697  1   53.64  ? 660 HOH C O   1 
HETATM 9376 O  O   . HOH T 4 .   ? -54.203 27.834  49.956  1   45.28  ? 661 HOH C O   1 
HETATM 9377 O  O   . HOH T 4 .   ? -43.417 33.011  35.897  1   38.25  ? 662 HOH C O   1 
HETATM 9378 O  O   . HOH T 4 .   ? -34.845 13.598  32.67   1   37.24  ? 663 HOH C O   1 
HETATM 9379 O  O   . HOH T 4 .   ? -54.323 -4.822  43.349  1   48.15  ? 664 HOH C O   1 
HETATM 9380 O  O   . HOH T 4 .   ? -38.689 19.005  15.44   1   48.81  ? 665 HOH C O   1 
HETATM 9381 O  O   . HOH T 4 .   ? -43.306 -1.325  35.447  1   42.2   ? 666 HOH C O   1 
HETATM 9382 O  O   . HOH T 4 .   ? -35.871 3.633   42.564  1   46.11  ? 667 HOH C O   1 
HETATM 9383 O  O   . HOH T 4 .   ? -13.786 5.549   20.591  1   55.37  ? 668 HOH C O   1 
HETATM 9384 O  O   . HOH T 4 .   ? -26.256 17.868  18.072  1   46.13  ? 669 HOH C O   1 
HETATM 9385 O  O   . HOH T 4 .   ? -68.253 25.621  43.537  1   46.4   ? 670 HOH C O   1 
HETATM 9386 O  O   . HOH T 4 .   ? -35.696 11.74   30.204  1   46.71  ? 671 HOH C O   1 
HETATM 9387 O  O   . HOH T 4 .   ? -54.425 29.72   39.354  1   45.87  ? 672 HOH C O   1 
HETATM 9388 O  O   . HOH T 4 .   ? -47.251 11.738  47.214  1   45.71  ? 673 HOH C O   1 
HETATM 9389 O  O   . HOH T 4 .   ? -49.077 2.158   47.413  1   31.6   ? 674 HOH C O   1 
HETATM 9390 O  O   . HOH T 4 .   ? -51.513 5.497   20.02   1   46.58  ? 675 HOH C O   1 
HETATM 9391 O  O   . HOH T 4 .   ? -61.672 2.949   45.401  1   41.46  ? 676 HOH C O   1 
HETATM 9392 O  O   . HOH T 4 .   ? -18.976 6.954   22.381  1   47.34  ? 677 HOH C O   1 
HETATM 9393 O  O   . HOH T 4 .   ? -38.412 -0.321  44.618  1   46.02  ? 678 HOH C O   1 
HETATM 9394 O  O   . HOH T 4 .   ? -26.26  8.254   19.409  1   53.41  ? 679 HOH C O   1 
HETATM 9395 O  O   . HOH T 4 .   ? -33.128 22.115  20.859  1   42.96  ? 680 HOH C O   1 
HETATM 9396 O  O   . HOH T 4 .   ? -61.03  2.136   42.827  1   50.25  ? 681 HOH C O   1 
HETATM 9397 O  O   . HOH T 4 .   ? -16.68  9.298   33.345  1   52.94  ? 682 HOH C O   1 
HETATM 9398 O  O   . HOH T 4 .   ? -24.821 4.68    20.535  1   53.75  ? 683 HOH C O   1 
HETATM 9399 O  O   . HOH T 4 .   ? -35.486 30.626  29.799  1   49.79  ? 684 HOH C O   1 
HETATM 9400 O  O   . HOH T 4 .   ? -63.192 30.872  43.064  1   40.62  ? 685 HOH C O   1 
HETATM 9401 O  O   . HOH T 4 .   ? -24.621 8.414   21.676  1   42.05  ? 686 HOH C O   1 
HETATM 9402 O  O   . HOH T 4 .   ? -39.491 6.507   42.115  1   45.41  ? 687 HOH C O   1 
HETATM 9403 O  O   . HOH U 4 .   ? -28.025 -29.872 29.658  1   29.7   ? 601 HOH D O   1 
HETATM 9404 O  O   . HOH U 4 .   ? -47.893 -13.47  19.686  1   47.56  ? 602 HOH D O   1 
HETATM 9405 O  O   . HOH U 4 .   ? -49.319 -17.879 18.504  1   48.92  ? 603 HOH D O   1 
HETATM 9406 O  O   . HOH U 4 .   ? -42.236 -15.005 25.078  1   43.64  ? 604 HOH D O   1 
HETATM 9407 O  O   . HOH U 4 .   ? -53.383 -31.239 41.214  1   55.79  ? 605 HOH D O   1 
HETATM 9408 O  O   . HOH U 4 .   ? -32.501 -32.249 38.816  1   37.02  ? 606 HOH D O   1 
HETATM 9409 O  O   . HOH U 4 .   ? -45.368 -6.851  34.121  1   39.6   ? 607 HOH D O   1 
HETATM 9410 O  O   . HOH U 4 .   ? -40.329 -1.563  42.611  1   32.14  ? 608 HOH D O   1 
HETATM 9411 O  O   . HOH U 4 .   ? -44.559 -26.848 41.772  1   47.93  ? 609 HOH D O   1 
HETATM 9412 O  O   . HOH U 4 .   ? -52.589 -8.129  33.951  1   50.52  ? 610 HOH D O   1 
HETATM 9413 O  O   . HOH U 4 .   ? -43.644 -20.276 50.574  1   49.06  ? 611 HOH D O   1 
HETATM 9414 O  O   . HOH U 4 .   ? -23.473 -10.999 51.794  1   50.02  ? 612 HOH D O   1 
HETATM 9415 O  O   . HOH U 4 .   ? -24.599 -25.371 31.873  1   40.72  ? 613 HOH D O   1 
HETATM 9416 O  O   . HOH U 4 .   ? -26.639 -4.6    40.747  1   35.6   ? 614 HOH D O   1 
HETATM 9417 O  O   . HOH U 4 .   ? -45.173 -3.255  36.072  1   36.6   ? 615 HOH D O   1 
HETATM 9418 O  O   . HOH U 4 .   ? -37.838 -27.39  33.662  1   37.36  ? 616 HOH D O   1 
HETATM 9419 O  O   . HOH U 4 .   ? -45.549 -17.65  44.465  1   44.96  ? 617 HOH D O   1 
HETATM 9420 O  O   . HOH U 4 .   ? -55.353 8.106   27.438  1   49.38  ? 618 HOH D O   1 
HETATM 9421 O  O   . HOH U 4 .   ? -45.556 -31.305 32.651  1   48.98  ? 619 HOH D O   1 
HETATM 9422 O  O   . HOH U 4 .   ? -21.806 -8      37      1   40.2   ? 620 HOH D O   1 
HETATM 9423 O  O   . HOH U 4 .   ? -40.011 -18.537 29.723  1   47.7   ? 621 HOH D O   1 
HETATM 9424 O  O   . HOH U 4 .   ? -42.125 -28.967 45.467  1   40.2   ? 622 HOH D O   1 
HETATM 9425 O  O   . HOH U 4 .   ? -35.587 -4.303  46.588  1   59.28  ? 623 HOH D O   1 
HETATM 9426 O  O   . HOH U 4 .   ? -37.526 -26.328 44.75   1   50.95  ? 624 HOH D O   1 
HETATM 9427 O  O   . HOH U 4 .   ? -39.717 -1.854  49.042  1   47.46  ? 625 HOH D O   1 
HETATM 9428 O  O   . HOH U 4 .   ? -44.482 -28.93  39.445  1   39.23  ? 626 HOH D O   1 
HETATM 9429 O  O   . HOH U 4 .   ? -49.814 -5.782  30.235  1   46.36  ? 627 HOH D O   1 
HETATM 9430 O  O   . HOH U 4 .   ? -21.228 -25.654 40.06   1   33.62  ? 628 HOH D O   1 
HETATM 9431 O  O   . HOH U 4 .   ? -46.95  -28.314 42.083  1   61.18  ? 629 HOH D O   1 
HETATM 9432 O  O   . HOH U 4 .   ? -41.46  -34.508 38.315  1   53.75  ? 630 HOH D O   1 
HETATM 9433 O  O   . HOH U 4 .   ? -47.221 -8.18   46.038  1   40.76  ? 631 HOH D O   1 
HETATM 9434 O  O   . HOH U 4 .   ? -31.936 -21.938 49.528  1   37.73  ? 632 HOH D O   1 
HETATM 9435 O  O   . HOH U 4 .   ? -45.587 -16.194 31.801  1   40.22  ? 633 HOH D O   1 
HETATM 9436 O  O   . HOH U 4 .   ? -40.787 0.958   46.807  1   51.11  ? 634 HOH D O   1 
HETATM 9437 O  O   . HOH U 4 .   ? -45.681 -4.774  46.538  1   34.73  ? 635 HOH D O   1 
HETATM 9438 O  O   . HOH U 4 .   ? -27.527 -23.57  45.028  1   33.41  ? 636 HOH D O   1 
HETATM 9439 O  O   . HOH U 4 .   ? -27.637 -23.34  42.31   1   31     ? 637 HOH D O   1 
HETATM 9440 O  O   . HOH U 4 .   ? -35.389 -27.474 27.185  1   65.74  ? 638 HOH D O   1 
HETATM 9441 O  O   . HOH U 4 .   ? -52.338 -7.16   29.858  1   51.28  ? 639 HOH D O   1 
HETATM 9442 O  O   . HOH U 4 .   ? -33.963 -33.096 33.224  1   40.18  ? 640 HOH D O   1 
HETATM 9443 O  O   . HOH U 4 .   ? -32.949 -32.027 30.31   1   39.86  ? 641 HOH D O   1 
HETATM 9444 O  O   . HOH U 4 .   ? -50.024 -10.742 39.546  1   45.08  ? 642 HOH D O   1 
HETATM 9445 O  O   . HOH U 4 .   ? -50.682 -12.413 42.781  1   48.22  ? 643 HOH D O   1 
HETATM 9446 O  O   . HOH U 4 .   ? -17.593 -18.142 42.649  1   55.08  ? 644 HOH D O   1 
HETATM 9447 O  O   . HOH U 4 .   ? -47.35  -33.008 35.761  1   51.28  ? 645 HOH D O   1 
HETATM 9448 O  O   . HOH U 4 .   ? -58.673 -0.806  21.917  1   57.09  ? 646 HOH D O   1 
HETATM 9449 O  O   . HOH U 4 .   ? -45.368 -28.618 36.755  1   48.94  ? 647 HOH D O   1 
HETATM 9450 O  O   . HOH U 4 .   ? -50.876 -25.186 20.775  1   49.28  ? 648 HOH D O   1 
HETATM 9451 O  O   . HOH U 4 .   ? -47.129 -4.788  43.923  1   38.2   ? 649 HOH D O   1 
HETATM 9452 O  O   . HOH U 4 .   ? -24.824 -2.937  41.691  1   40.2   ? 650 HOH D O   1 
HETATM 9453 O  O   . HOH U 4 .   ? -49.944 -17.546 37.684  1   58.72  ? 651 HOH D O   1 
HETATM 9454 O  O   . HOH U 4 .   ? -51.894 -33.348 47.754  1   65.01  ? 652 HOH D O   1 
HETATM 9455 O  O   . HOH U 4 .   ? -48.954 -31.89  22.042  1   53.91  ? 653 HOH D O   1 
HETATM 9456 O  O   . HOH U 4 .   ? -59.908 5.019   37.999  1   46.42  ? 654 HOH D O   1 
HETATM 9457 O  O   . HOH U 4 .   ? -18.827 -12.063 47.203  1   56.41  ? 655 HOH D O   1 
HETATM 9458 O  O   . HOH U 4 .   ? -39.175 -30.377 31.518  1   43.78  ? 656 HOH D O   1 
HETATM 9459 O  O   . HOH U 4 .   ? -24.161 -29.695 26.356  1   40.35  ? 657 HOH D O   1 
HETATM 9460 O  O   . HOH U 4 .   ? -63.108 1.002   35.615  1   51.21  ? 658 HOH D O   1 
HETATM 9461 O  O   . HOH U 4 .   ? -26.664 -21.332 26.115  1   43.44  ? 659 HOH D O   1 
HETATM 9462 O  O   . HOH U 4 .   ? -44.059 -6.483  31.796  1   39.67  ? 660 HOH D O   1 
HETATM 9463 O  O   . HOH U 4 .   ? -20.14  -18.073 48.213  1   58.79  ? 661 HOH D O   1 
HETATM 9464 O  O   . HOH U 4 .   ? -27.843 -7.365  54.489  1   46.13  ? 662 HOH D O   1 
HETATM 9465 O  O   . HOH U 4 .   ? -37.408 -32.763 31.268  1   47.24  ? 663 HOH D O   1 
HETATM 9466 O  O   . HOH U 4 .   ? -30.537 -31.058 29.731  1   46.93  ? 664 HOH D O   1 
HETATM 9467 O  O   . HOH U 4 .   ? -37.791 -27.533 25.302  1   56.26  ? 665 HOH D O   1 
HETATM 9468 O  O   . HOH U 4 .   ? -21.545 -15.967 27.122  1   49.53  ? 666 HOH D O   1 
HETATM 9469 O  O   . HOH U 4 .   ? -26.617 -9.683  53.172  1   42.2   ? 667 HOH D O   1 
# 
