data_9ETB
# 
_entry.id   9ETB 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ETB         pdb_00009etb 10.2210/pdb9etb/pdb 
WWPDB D_1292137009 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ETB 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Cyclin-A2                                             30817.473 2   ?         ? ? ? 
2 polymer     man 'Cyclin-dependent kinase 2'                           34354.770 2   2.7.11.22 ? ? ? 
3 non-polymer syn 4-IODOPYRAZOLE                                        193.974   12  ?         ? ? ? 
4 non-polymer syn '4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID' 238.305   1   ?         ? ? ? 
5 water       nat water                                                 18.015    244 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 Cyclin-A                                            
2 'Cell division protein kinase 2,p33 protein kinase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
D,B ? 
2 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 4-IODOPYRAZOLE                                        PYZ 
4 '4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID' EPE 
5 water                                                 HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   VAL n 
1 3   ASN n 
1 4   GLU n 
1 5   VAL n 
1 6   PRO n 
1 7   ASP n 
1 8   TYR n 
1 9   HIS n 
1 10  GLU n 
1 11  ASP n 
1 12  ILE n 
1 13  HIS n 
1 14  THR n 
1 15  TYR n 
1 16  LEU n 
1 17  ARG n 
1 18  GLU n 
1 19  MET n 
1 20  GLU n 
1 21  VAL n 
1 22  LYS n 
1 23  CYS n 
1 24  LYS n 
1 25  PRO n 
1 26  LYS n 
1 27  VAL n 
1 28  GLY n 
1 29  TYR n 
1 30  MET n 
1 31  LYS n 
1 32  LYS n 
1 33  GLN n 
1 34  PRO n 
1 35  ASP n 
1 36  ILE n 
1 37  THR n 
1 38  ASN n 
1 39  SER n 
1 40  MET n 
1 41  ARG n 
1 42  ALA n 
1 43  ILE n 
1 44  LEU n 
1 45  VAL n 
1 46  ASP n 
1 47  TRP n 
1 48  LEU n 
1 49  VAL n 
1 50  GLU n 
1 51  VAL n 
1 52  GLY n 
1 53  GLU n 
1 54  GLU n 
1 55  TYR n 
1 56  LYS n 
1 57  LEU n 
1 58  GLN n 
1 59  ASN n 
1 60  GLU n 
1 61  THR n 
1 62  LEU n 
1 63  HIS n 
1 64  LEU n 
1 65  ALA n 
1 66  VAL n 
1 67  ASN n 
1 68  TYR n 
1 69  ILE n 
1 70  ASP n 
1 71  ARG n 
1 72  PHE n 
1 73  LEU n 
1 74  SER n 
1 75  SER n 
1 76  MET n 
1 77  SER n 
1 78  VAL n 
1 79  LEU n 
1 80  ARG n 
1 81  GLY n 
1 82  LYS n 
1 83  LEU n 
1 84  GLN n 
1 85  LEU n 
1 86  VAL n 
1 87  GLY n 
1 88  THR n 
1 89  ALA n 
1 90  ALA n 
1 91  MET n 
1 92  LEU n 
1 93  LEU n 
1 94  ALA n 
1 95  SER n 
1 96  LYS n 
1 97  PHE n 
1 98  GLU n 
1 99  GLU n 
1 100 ILE n 
1 101 TYR n 
1 102 PRO n 
1 103 PRO n 
1 104 GLU n 
1 105 VAL n 
1 106 ALA n 
1 107 GLU n 
1 108 PHE n 
1 109 VAL n 
1 110 TYR n 
1 111 ILE n 
1 112 THR n 
1 113 ASP n 
1 114 ASP n 
1 115 THR n 
1 116 TYR n 
1 117 THR n 
1 118 LYS n 
1 119 LYS n 
1 120 GLN n 
1 121 VAL n 
1 122 LEU n 
1 123 ARG n 
1 124 MET n 
1 125 GLU n 
1 126 HIS n 
1 127 LEU n 
1 128 VAL n 
1 129 LEU n 
1 130 LYS n 
1 131 VAL n 
1 132 LEU n 
1 133 ALA n 
1 134 PHE n 
1 135 ASP n 
1 136 LEU n 
1 137 ALA n 
1 138 ALA n 
1 139 PRO n 
1 140 THR n 
1 141 ILE n 
1 142 ASN n 
1 143 GLN n 
1 144 PHE n 
1 145 LEU n 
1 146 THR n 
1 147 GLN n 
1 148 TYR n 
1 149 PHE n 
1 150 LEU n 
1 151 HIS n 
1 152 GLN n 
1 153 GLN n 
1 154 PRO n 
1 155 ALA n 
1 156 ASN n 
1 157 CYS n 
1 158 LYS n 
1 159 VAL n 
1 160 GLU n 
1 161 SER n 
1 162 LEU n 
1 163 ALA n 
1 164 MET n 
1 165 PHE n 
1 166 LEU n 
1 167 GLY n 
1 168 GLU n 
1 169 LEU n 
1 170 SER n 
1 171 LEU n 
1 172 ILE n 
1 173 ASP n 
1 174 ALA n 
1 175 ASP n 
1 176 PRO n 
1 177 TYR n 
1 178 LEU n 
1 179 LYS n 
1 180 TYR n 
1 181 LEU n 
1 182 PRO n 
1 183 SER n 
1 184 VAL n 
1 185 ILE n 
1 186 ALA n 
1 187 ALA n 
1 188 ALA n 
1 189 ALA n 
1 190 PHE n 
1 191 HIS n 
1 192 LEU n 
1 193 ALA n 
1 194 LEU n 
1 195 TYR n 
1 196 THR n 
1 197 VAL n 
1 198 THR n 
1 199 GLY n 
1 200 GLN n 
1 201 SER n 
1 202 TRP n 
1 203 PRO n 
1 204 GLU n 
1 205 SER n 
1 206 LEU n 
1 207 VAL n 
1 208 GLN n 
1 209 LYS n 
1 210 THR n 
1 211 GLY n 
1 212 TYR n 
1 213 THR n 
1 214 LEU n 
1 215 GLU n 
1 216 THR n 
1 217 LEU n 
1 218 LYS n 
1 219 PRO n 
1 220 CYS n 
1 221 LEU n 
1 222 LEU n 
1 223 ASP n 
1 224 LEU n 
1 225 HIS n 
1 226 GLN n 
1 227 THR n 
1 228 TYR n 
1 229 LEU n 
1 230 ARG n 
1 231 ALA n 
1 232 PRO n 
1 233 GLN n 
1 234 HIS n 
1 235 ALA n 
1 236 GLN n 
1 237 GLN n 
1 238 SER n 
1 239 ILE n 
1 240 ARG n 
1 241 GLU n 
1 242 LYS n 
1 243 TYR n 
1 244 LYS n 
1 245 ASN n 
1 246 SER n 
1 247 LYS n 
1 248 TYR n 
1 249 HIS n 
1 250 GLY n 
1 251 VAL n 
1 252 SER n 
1 253 LEU n 
1 254 LEU n 
1 255 ASN n 
1 256 PRO n 
1 257 PRO n 
1 258 GLU n 
1 259 THR n 
1 260 LEU n 
1 261 ASN n 
1 262 VAL n 
1 263 HIS n 
1 264 HIS n 
1 265 HIS n 
1 266 HIS n 
1 267 HIS n 
1 268 HIS n 
2 1   GLY n 
2 2   PRO n 
2 3   GLY n 
2 4   SER n 
2 5   MET n 
2 6   GLU n 
2 7   ASN n 
2 8   PHE n 
2 9   GLN n 
2 10  LYS n 
2 11  VAL n 
2 12  GLU n 
2 13  LYS n 
2 14  ILE n 
2 15  GLY n 
2 16  GLU n 
2 17  GLY n 
2 18  THR n 
2 19  TYR n 
2 20  GLY n 
2 21  VAL n 
2 22  VAL n 
2 23  TYR n 
2 24  LYS n 
2 25  ALA n 
2 26  ARG n 
2 27  ASN n 
2 28  LYS n 
2 29  LEU n 
2 30  THR n 
2 31  GLY n 
2 32  GLU n 
2 33  VAL n 
2 34  VAL n 
2 35  ALA n 
2 36  LEU n 
2 37  LYS n 
2 38  LYS n 
2 39  ILE n 
2 40  ARG n 
2 41  LEU n 
2 42  ASP n 
2 43  THR n 
2 44  GLU n 
2 45  THR n 
2 46  GLU n 
2 47  GLY n 
2 48  VAL n 
2 49  PRO n 
2 50  SER n 
2 51  THR n 
2 52  ALA n 
2 53  ILE n 
2 54  ARG n 
2 55  GLU n 
2 56  ILE n 
2 57  SER n 
2 58  LEU n 
2 59  LEU n 
2 60  LYS n 
2 61  GLU n 
2 62  LEU n 
2 63  ASN n 
2 64  HIS n 
2 65  PRO n 
2 66  ASN n 
2 67  ILE n 
2 68  VAL n 
2 69  LYS n 
2 70  LEU n 
2 71  LEU n 
2 72  ASP n 
2 73  VAL n 
2 74  ILE n 
2 75  HIS n 
2 76  THR n 
2 77  GLU n 
2 78  ASN n 
2 79  LYS n 
2 80  LEU n 
2 81  TYR n 
2 82  LEU n 
2 83  VAL n 
2 84  PHE n 
2 85  GLU n 
2 86  PHE n 
2 87  LEU n 
2 88  HIS n 
2 89  GLN n 
2 90  ASP n 
2 91  LEU n 
2 92  LYS n 
2 93  LYS n 
2 94  PHE n 
2 95  MET n 
2 96  ASP n 
2 97  ALA n 
2 98  SER n 
2 99  ALA n 
2 100 LEU n 
2 101 THR n 
2 102 GLY n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 PRO n 
2 107 LEU n 
2 108 ILE n 
2 109 LYS n 
2 110 SER n 
2 111 TYR n 
2 112 LEU n 
2 113 PHE n 
2 114 GLN n 
2 115 LEU n 
2 116 LEU n 
2 117 GLN n 
2 118 GLY n 
2 119 LEU n 
2 120 ALA n 
2 121 PHE n 
2 122 CYS n 
2 123 HIS n 
2 124 SER n 
2 125 HIS n 
2 126 ARG n 
2 127 VAL n 
2 128 LEU n 
2 129 HIS n 
2 130 ARG n 
2 131 ASP n 
2 132 LEU n 
2 133 LYS n 
2 134 PRO n 
2 135 GLN n 
2 136 ASN n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ASN n 
2 141 THR n 
2 142 GLU n 
2 143 GLY n 
2 144 ALA n 
2 145 ILE n 
2 146 LYS n 
2 147 LEU n 
2 148 ALA n 
2 149 ASP n 
2 150 PHE n 
2 151 GLY n 
2 152 LEU n 
2 153 ALA n 
2 154 ARG n 
2 155 ALA n 
2 156 PHE n 
2 157 GLY n 
2 158 VAL n 
2 159 PRO n 
2 160 VAL n 
2 161 ARG n 
2 162 THR n 
2 163 TYR n 
2 164 TPO n 
2 165 HIS n 
2 166 GLU n 
2 167 VAL n 
2 168 VAL n 
2 169 THR n 
2 170 LEU n 
2 171 TRP n 
2 172 TYR n 
2 173 ARG n 
2 174 ALA n 
2 175 PRO n 
2 176 GLU n 
2 177 ILE n 
2 178 LEU n 
2 179 LEU n 
2 180 GLY n 
2 181 CYS n 
2 182 LYS n 
2 183 TYR n 
2 184 TYR n 
2 185 SER n 
2 186 THR n 
2 187 ALA n 
2 188 VAL n 
2 189 ASP n 
2 190 ILE n 
2 191 TRP n 
2 192 SER n 
2 193 LEU n 
2 194 GLY n 
2 195 CYS n 
2 196 ILE n 
2 197 PHE n 
2 198 ALA n 
2 199 GLU n 
2 200 MET n 
2 201 VAL n 
2 202 THR n 
2 203 ARG n 
2 204 ARG n 
2 205 ALA n 
2 206 LEU n 
2 207 PHE n 
2 208 PRO n 
2 209 GLY n 
2 210 ASP n 
2 211 SER n 
2 212 GLU n 
2 213 ILE n 
2 214 ASP n 
2 215 GLN n 
2 216 LEU n 
2 217 PHE n 
2 218 ARG n 
2 219 ILE n 
2 220 PHE n 
2 221 ARG n 
2 222 THR n 
2 223 LEU n 
2 224 GLY n 
2 225 THR n 
2 226 PRO n 
2 227 ASP n 
2 228 GLU n 
2 229 VAL n 
2 230 VAL n 
2 231 TRP n 
2 232 PRO n 
2 233 GLY n 
2 234 VAL n 
2 235 THR n 
2 236 SER n 
2 237 MET n 
2 238 PRO n 
2 239 ASP n 
2 240 TYR n 
2 241 LYS n 
2 242 PRO n 
2 243 SER n 
2 244 PHE n 
2 245 PRO n 
2 246 LYS n 
2 247 TRP n 
2 248 ALA n 
2 249 ARG n 
2 250 GLN n 
2 251 ASP n 
2 252 PHE n 
2 253 SER n 
2 254 LYS n 
2 255 VAL n 
2 256 VAL n 
2 257 PRO n 
2 258 PRO n 
2 259 LEU n 
2 260 ASP n 
2 261 GLU n 
2 262 ASP n 
2 263 GLY n 
2 264 ARG n 
2 265 SER n 
2 266 LEU n 
2 267 LEU n 
2 268 SER n 
2 269 GLN n 
2 270 MET n 
2 271 LEU n 
2 272 HIS n 
2 273 TYR n 
2 274 ASP n 
2 275 PRO n 
2 276 ASN n 
2 277 LYS n 
2 278 ARG n 
2 279 ILE n 
2 280 SER n 
2 281 ALA n 
2 282 LYS n 
2 283 ALA n 
2 284 ALA n 
2 285 LEU n 
2 286 ALA n 
2 287 HIS n 
2 288 PRO n 
2 289 PHE n 
2 290 PHE n 
2 291 GLN n 
2 292 ASP n 
2 293 VAL n 
2 294 THR n 
2 295 LYS n 
2 296 PRO n 
2 297 VAL n 
2 298 PRO n 
2 299 HIS n 
2 300 LEU n 
2 301 ARG n 
2 302 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
2 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                               ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                              ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                            ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                       ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                              ?                  'C3 H7 N O2 S'   121.158 
EPE non-polymer         . '4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID' HEPES              'C8 H18 N2 O4 S' 238.305 
GLN 'L-peptide linking' y GLUTAMINE                                             ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                       ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                               ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                             ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                                 ?                  'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                            ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                               ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                            ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                         ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                               ?                  'C5 H9 N O2'     115.130 
PYZ non-polymer         . 4-IODOPYRAZOLE                                        ?                  'C3 H3 I N2'     193.974 
SER 'L-peptide linking' y SERINE                                                ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                             ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE                                      PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN                                            ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                              ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   171 171 GLY GLY D . n 
A 1 2   VAL 2   172 172 VAL VAL D . n 
A 1 3   ASN 3   173 173 ASN ASN D . n 
A 1 4   GLU 4   174 174 GLU GLU D . n 
A 1 5   VAL 5   175 175 VAL VAL D . n 
A 1 6   PRO 6   176 176 PRO PRO D . n 
A 1 7   ASP 7   177 177 ASP ASP D . n 
A 1 8   TYR 8   178 178 TYR TYR D . n 
A 1 9   HIS 9   179 179 HIS HIS D . n 
A 1 10  GLU 10  180 180 GLU GLU D . n 
A 1 11  ASP 11  181 181 ASP ASP D . n 
A 1 12  ILE 12  182 182 ILE ILE D . n 
A 1 13  HIS 13  183 183 HIS HIS D . n 
A 1 14  THR 14  184 184 THR THR D . n 
A 1 15  TYR 15  185 185 TYR TYR D . n 
A 1 16  LEU 16  186 186 LEU LEU D . n 
A 1 17  ARG 17  187 187 ARG ARG D . n 
A 1 18  GLU 18  188 188 GLU GLU D . n 
A 1 19  MET 19  189 189 MET MET D . n 
A 1 20  GLU 20  190 190 GLU GLU D . n 
A 1 21  VAL 21  191 191 VAL VAL D . n 
A 1 22  LYS 22  192 192 LYS LYS D . n 
A 1 23  CYS 23  193 193 CYS CYS D . n 
A 1 24  LYS 24  194 194 LYS LYS D . n 
A 1 25  PRO 25  195 195 PRO PRO D . n 
A 1 26  LYS 26  196 196 LYS LYS D . n 
A 1 27  VAL 27  197 197 VAL VAL D . n 
A 1 28  GLY 28  198 198 GLY GLY D . n 
A 1 29  TYR 29  199 199 TYR TYR D . n 
A 1 30  MET 30  200 200 MET MET D . n 
A 1 31  LYS 31  201 201 LYS LYS D . n 
A 1 32  LYS 32  202 202 LYS LYS D . n 
A 1 33  GLN 33  203 203 GLN GLN D . n 
A 1 34  PRO 34  204 204 PRO PRO D . n 
A 1 35  ASP 35  205 205 ASP ASP D . n 
A 1 36  ILE 36  206 206 ILE ILE D . n 
A 1 37  THR 37  207 207 THR THR D . n 
A 1 38  ASN 38  208 208 ASN ASN D . n 
A 1 39  SER 39  209 209 SER SER D . n 
A 1 40  MET 40  210 210 MET MET D . n 
A 1 41  ARG 41  211 211 ARG ARG D . n 
A 1 42  ALA 42  212 212 ALA ALA D . n 
A 1 43  ILE 43  213 213 ILE ILE D . n 
A 1 44  LEU 44  214 214 LEU LEU D . n 
A 1 45  VAL 45  215 215 VAL VAL D . n 
A 1 46  ASP 46  216 216 ASP ASP D . n 
A 1 47  TRP 47  217 217 TRP TRP D . n 
A 1 48  LEU 48  218 218 LEU LEU D . n 
A 1 49  VAL 49  219 219 VAL VAL D . n 
A 1 50  GLU 50  220 220 GLU GLU D . n 
A 1 51  VAL 51  221 221 VAL VAL D . n 
A 1 52  GLY 52  222 222 GLY GLY D . n 
A 1 53  GLU 53  223 223 GLU GLU D . n 
A 1 54  GLU 54  224 224 GLU GLU D . n 
A 1 55  TYR 55  225 225 TYR TYR D . n 
A 1 56  LYS 56  226 226 LYS LYS D . n 
A 1 57  LEU 57  227 227 LEU LEU D . n 
A 1 58  GLN 58  228 228 GLN GLN D . n 
A 1 59  ASN 59  229 229 ASN ASN D . n 
A 1 60  GLU 60  230 230 GLU GLU D . n 
A 1 61  THR 61  231 231 THR THR D . n 
A 1 62  LEU 62  232 232 LEU LEU D . n 
A 1 63  HIS 63  233 233 HIS HIS D . n 
A 1 64  LEU 64  234 234 LEU LEU D . n 
A 1 65  ALA 65  235 235 ALA ALA D . n 
A 1 66  VAL 66  236 236 VAL VAL D . n 
A 1 67  ASN 67  237 237 ASN ASN D . n 
A 1 68  TYR 68  238 238 TYR TYR D . n 
A 1 69  ILE 69  239 239 ILE ILE D . n 
A 1 70  ASP 70  240 240 ASP ASP D . n 
A 1 71  ARG 71  241 241 ARG ARG D . n 
A 1 72  PHE 72  242 242 PHE PHE D . n 
A 1 73  LEU 73  243 243 LEU LEU D . n 
A 1 74  SER 74  244 244 SER SER D . n 
A 1 75  SER 75  245 245 SER SER D . n 
A 1 76  MET 76  246 246 MET MET D . n 
A 1 77  SER 77  247 247 SER SER D . n 
A 1 78  VAL 78  248 248 VAL VAL D . n 
A 1 79  LEU 79  249 249 LEU LEU D . n 
A 1 80  ARG 80  250 250 ARG ARG D . n 
A 1 81  GLY 81  251 251 GLY GLY D . n 
A 1 82  LYS 82  252 252 LYS LYS D . n 
A 1 83  LEU 83  253 253 LEU LEU D . n 
A 1 84  GLN 84  254 254 GLN GLN D . n 
A 1 85  LEU 85  255 255 LEU LEU D . n 
A 1 86  VAL 86  256 256 VAL VAL D . n 
A 1 87  GLY 87  257 257 GLY GLY D . n 
A 1 88  THR 88  258 258 THR THR D . n 
A 1 89  ALA 89  259 259 ALA ALA D . n 
A 1 90  ALA 90  260 260 ALA ALA D . n 
A 1 91  MET 91  261 261 MET MET D . n 
A 1 92  LEU 92  262 262 LEU LEU D . n 
A 1 93  LEU 93  263 263 LEU LEU D . n 
A 1 94  ALA 94  264 264 ALA ALA D . n 
A 1 95  SER 95  265 265 SER SER D . n 
A 1 96  LYS 96  266 266 LYS LYS D . n 
A 1 97  PHE 97  267 267 PHE PHE D . n 
A 1 98  GLU 98  268 268 GLU GLU D . n 
A 1 99  GLU 99  269 269 GLU GLU D . n 
A 1 100 ILE 100 270 270 ILE ILE D . n 
A 1 101 TYR 101 271 271 TYR TYR D . n 
A 1 102 PRO 102 272 272 PRO PRO D . n 
A 1 103 PRO 103 273 273 PRO PRO D . n 
A 1 104 GLU 104 274 274 GLU GLU D . n 
A 1 105 VAL 105 275 275 VAL VAL D . n 
A 1 106 ALA 106 276 276 ALA ALA D . n 
A 1 107 GLU 107 277 277 GLU GLU D . n 
A 1 108 PHE 108 278 278 PHE PHE D . n 
A 1 109 VAL 109 279 279 VAL VAL D . n 
A 1 110 TYR 110 280 280 TYR TYR D . n 
A 1 111 ILE 111 281 281 ILE ILE D . n 
A 1 112 THR 112 282 282 THR THR D . n 
A 1 113 ASP 113 283 283 ASP ASP D . n 
A 1 114 ASP 114 284 284 ASP ASP D . n 
A 1 115 THR 115 285 285 THR THR D . n 
A 1 116 TYR 116 286 286 TYR TYR D . n 
A 1 117 THR 117 287 287 THR THR D . n 
A 1 118 LYS 118 288 288 LYS LYS D . n 
A 1 119 LYS 119 289 289 LYS LYS D . n 
A 1 120 GLN 120 290 290 GLN GLN D . n 
A 1 121 VAL 121 291 291 VAL VAL D . n 
A 1 122 LEU 122 292 292 LEU LEU D . n 
A 1 123 ARG 123 293 293 ARG ARG D . n 
A 1 124 MET 124 294 294 MET MET D . n 
A 1 125 GLU 125 295 295 GLU GLU D . n 
A 1 126 HIS 126 296 296 HIS HIS D . n 
A 1 127 LEU 127 297 297 LEU LEU D . n 
A 1 128 VAL 128 298 298 VAL VAL D . n 
A 1 129 LEU 129 299 299 LEU LEU D . n 
A 1 130 LYS 130 300 300 LYS LYS D . n 
A 1 131 VAL 131 301 301 VAL VAL D . n 
A 1 132 LEU 132 302 302 LEU LEU D . n 
A 1 133 ALA 133 303 303 ALA ALA D . n 
A 1 134 PHE 134 304 304 PHE PHE D . n 
A 1 135 ASP 135 305 305 ASP ASP D . n 
A 1 136 LEU 136 306 306 LEU LEU D . n 
A 1 137 ALA 137 307 307 ALA ALA D . n 
A 1 138 ALA 138 308 308 ALA ALA D . n 
A 1 139 PRO 139 309 309 PRO PRO D . n 
A 1 140 THR 140 310 310 THR THR D . n 
A 1 141 ILE 141 311 311 ILE ILE D . n 
A 1 142 ASN 142 312 312 ASN ASN D . n 
A 1 143 GLN 143 313 313 GLN GLN D . n 
A 1 144 PHE 144 314 314 PHE PHE D . n 
A 1 145 LEU 145 315 315 LEU LEU D . n 
A 1 146 THR 146 316 316 THR THR D . n 
A 1 147 GLN 147 317 317 GLN GLN D . n 
A 1 148 TYR 148 318 318 TYR TYR D . n 
A 1 149 PHE 149 319 319 PHE PHE D . n 
A 1 150 LEU 150 320 320 LEU LEU D . n 
A 1 151 HIS 151 321 321 HIS HIS D . n 
A 1 152 GLN 152 322 322 GLN GLN D . n 
A 1 153 GLN 153 323 323 GLN GLN D . n 
A 1 154 PRO 154 324 324 PRO PRO D . n 
A 1 155 ALA 155 325 325 ALA ALA D . n 
A 1 156 ASN 156 326 326 ASN ASN D . n 
A 1 157 CYS 157 327 327 CYS CYS D . n 
A 1 158 LYS 158 328 328 LYS LYS D . n 
A 1 159 VAL 159 329 329 VAL VAL D . n 
A 1 160 GLU 160 330 330 GLU GLU D . n 
A 1 161 SER 161 331 331 SER SER D . n 
A 1 162 LEU 162 332 332 LEU LEU D . n 
A 1 163 ALA 163 333 333 ALA ALA D . n 
A 1 164 MET 164 334 334 MET MET D . n 
A 1 165 PHE 165 335 335 PHE PHE D . n 
A 1 166 LEU 166 336 336 LEU LEU D . n 
A 1 167 GLY 167 337 337 GLY GLY D . n 
A 1 168 GLU 168 338 338 GLU GLU D . n 
A 1 169 LEU 169 339 339 LEU LEU D . n 
A 1 170 SER 170 340 340 SER SER D . n 
A 1 171 LEU 171 341 341 LEU LEU D . n 
A 1 172 ILE 172 342 342 ILE ILE D . n 
A 1 173 ASP 173 343 343 ASP ASP D . n 
A 1 174 ALA 174 344 344 ALA ALA D . n 
A 1 175 ASP 175 345 345 ASP ASP D . n 
A 1 176 PRO 176 346 346 PRO PRO D . n 
A 1 177 TYR 177 347 347 TYR TYR D . n 
A 1 178 LEU 178 348 348 LEU LEU D . n 
A 1 179 LYS 179 349 349 LYS LYS D . n 
A 1 180 TYR 180 350 350 TYR TYR D . n 
A 1 181 LEU 181 351 351 LEU LEU D . n 
A 1 182 PRO 182 352 352 PRO PRO D . n 
A 1 183 SER 183 353 353 SER SER D . n 
A 1 184 VAL 184 354 354 VAL VAL D . n 
A 1 185 ILE 185 355 355 ILE ILE D . n 
A 1 186 ALA 186 356 356 ALA ALA D . n 
A 1 187 ALA 187 357 357 ALA ALA D . n 
A 1 188 ALA 188 358 358 ALA ALA D . n 
A 1 189 ALA 189 359 359 ALA ALA D . n 
A 1 190 PHE 190 360 360 PHE PHE D . n 
A 1 191 HIS 191 361 361 HIS HIS D . n 
A 1 192 LEU 192 362 362 LEU LEU D . n 
A 1 193 ALA 193 363 363 ALA ALA D . n 
A 1 194 LEU 194 364 364 LEU LEU D . n 
A 1 195 TYR 195 365 365 TYR TYR D . n 
A 1 196 THR 196 366 366 THR THR D . n 
A 1 197 VAL 197 367 367 VAL VAL D . n 
A 1 198 THR 198 368 368 THR THR D . n 
A 1 199 GLY 199 369 369 GLY GLY D . n 
A 1 200 GLN 200 370 370 GLN GLN D . n 
A 1 201 SER 201 371 371 SER SER D . n 
A 1 202 TRP 202 372 372 TRP TRP D . n 
A 1 203 PRO 203 373 373 PRO PRO D . n 
A 1 204 GLU 204 374 374 GLU GLU D . n 
A 1 205 SER 205 375 375 SER SER D . n 
A 1 206 LEU 206 376 376 LEU LEU D . n 
A 1 207 VAL 207 377 377 VAL VAL D . n 
A 1 208 GLN 208 378 378 GLN GLN D . n 
A 1 209 LYS 209 379 379 LYS LYS D . n 
A 1 210 THR 210 380 380 THR THR D . n 
A 1 211 GLY 211 381 381 GLY GLY D . n 
A 1 212 TYR 212 382 382 TYR TYR D . n 
A 1 213 THR 213 383 383 THR THR D . n 
A 1 214 LEU 214 384 384 LEU LEU D . n 
A 1 215 GLU 215 385 385 GLU GLU D . n 
A 1 216 THR 216 386 386 THR THR D . n 
A 1 217 LEU 217 387 387 LEU LEU D . n 
A 1 218 LYS 218 388 388 LYS LYS D . n 
A 1 219 PRO 219 389 389 PRO PRO D . n 
A 1 220 CYS 220 390 390 CYS CYS D . n 
A 1 221 LEU 221 391 391 LEU LEU D . n 
A 1 222 LEU 222 392 392 LEU LEU D . n 
A 1 223 ASP 223 393 393 ASP ASP D . n 
A 1 224 LEU 224 394 394 LEU LEU D . n 
A 1 225 HIS 225 395 395 HIS HIS D . n 
A 1 226 GLN 226 396 396 GLN GLN D . n 
A 1 227 THR 227 397 397 THR THR D . n 
A 1 228 TYR 228 398 398 TYR TYR D . n 
A 1 229 LEU 229 399 399 LEU LEU D . n 
A 1 230 ARG 230 400 400 ARG ARG D . n 
A 1 231 ALA 231 401 401 ALA ALA D . n 
A 1 232 PRO 232 402 402 PRO PRO D . n 
A 1 233 GLN 233 403 403 GLN GLN D . n 
A 1 234 HIS 234 404 404 HIS HIS D . n 
A 1 235 ALA 235 405 405 ALA ALA D . n 
A 1 236 GLN 236 406 406 GLN GLN D . n 
A 1 237 GLN 237 407 407 GLN GLN D . n 
A 1 238 SER 238 408 408 SER SER D . n 
A 1 239 ILE 239 409 409 ILE ILE D . n 
A 1 240 ARG 240 410 410 ARG ARG D . n 
A 1 241 GLU 241 411 411 GLU GLU D . n 
A 1 242 LYS 242 412 412 LYS LYS D . n 
A 1 243 TYR 243 413 413 TYR TYR D . n 
A 1 244 LYS 244 414 414 LYS LYS D . n 
A 1 245 ASN 245 415 415 ASN ASN D . n 
A 1 246 SER 246 416 416 SER SER D . n 
A 1 247 LYS 247 417 417 LYS LYS D . n 
A 1 248 TYR 248 418 418 TYR TYR D . n 
A 1 249 HIS 249 419 419 HIS HIS D . n 
A 1 250 GLY 250 420 420 GLY GLY D . n 
A 1 251 VAL 251 421 421 VAL VAL D . n 
A 1 252 SER 252 422 422 SER SER D . n 
A 1 253 LEU 253 423 423 LEU LEU D . n 
A 1 254 LEU 254 424 424 LEU LEU D . n 
A 1 255 ASN 255 425 425 ASN ASN D . n 
A 1 256 PRO 256 426 426 PRO PRO D . n 
A 1 257 PRO 257 427 427 PRO PRO D . n 
A 1 258 GLU 258 428 428 GLU GLU D . n 
A 1 259 THR 259 429 429 THR THR D . n 
A 1 260 LEU 260 430 430 LEU LEU D . n 
A 1 261 ASN 261 431 431 ASN ASN D . n 
A 1 262 VAL 262 432 432 VAL VAL D . n 
A 1 263 HIS 263 433 ?   ?   ?   D . n 
A 1 264 HIS 264 434 ?   ?   ?   D . n 
A 1 265 HIS 265 435 ?   ?   ?   D . n 
A 1 266 HIS 266 436 ?   ?   ?   D . n 
A 1 267 HIS 267 437 ?   ?   ?   D . n 
A 1 268 HIS 268 438 ?   ?   ?   D . n 
B 2 1   GLY 1   -3  ?   ?   ?   A . n 
B 2 2   PRO 2   -2  -2  PRO PRO A . n 
B 2 3   GLY 3   -1  -1  GLY GLY A . n 
B 2 4   SER 4   0   0   SER SER A . n 
B 2 5   MET 5   1   1   MET MET A . n 
B 2 6   GLU 6   2   2   GLU GLU A . n 
B 2 7   ASN 7   3   3   ASN ASN A . n 
B 2 8   PHE 8   4   4   PHE PHE A . n 
B 2 9   GLN 9   5   5   GLN GLN A . n 
B 2 10  LYS 10  6   6   LYS LYS A . n 
B 2 11  VAL 11  7   7   VAL VAL A . n 
B 2 12  GLU 12  8   8   GLU GLU A . n 
B 2 13  LYS 13  9   9   LYS LYS A . n 
B 2 14  ILE 14  10  10  ILE ILE A . n 
B 2 15  GLY 15  11  11  GLY GLY A . n 
B 2 16  GLU 16  12  12  GLU GLU A . n 
B 2 17  GLY 17  13  13  GLY GLY A . n 
B 2 18  THR 18  14  14  THR THR A . n 
B 2 19  TYR 19  15  15  TYR TYR A . n 
B 2 20  GLY 20  16  16  GLY GLY A . n 
B 2 21  VAL 21  17  17  VAL VAL A . n 
B 2 22  VAL 22  18  18  VAL VAL A . n 
B 2 23  TYR 23  19  19  TYR TYR A . n 
B 2 24  LYS 24  20  20  LYS LYS A . n 
B 2 25  ALA 25  21  21  ALA ALA A . n 
B 2 26  ARG 26  22  22  ARG ARG A . n 
B 2 27  ASN 27  23  23  ASN ASN A . n 
B 2 28  LYS 28  24  24  LYS LYS A . n 
B 2 29  LEU 29  25  25  LEU LEU A . n 
B 2 30  THR 30  26  26  THR THR A . n 
B 2 31  GLY 31  27  27  GLY GLY A . n 
B 2 32  GLU 32  28  28  GLU GLU A . n 
B 2 33  VAL 33  29  29  VAL VAL A . n 
B 2 34  VAL 34  30  30  VAL VAL A . n 
B 2 35  ALA 35  31  31  ALA ALA A . n 
B 2 36  LEU 36  32  32  LEU LEU A . n 
B 2 37  LYS 37  33  33  LYS LYS A . n 
B 2 38  LYS 38  34  34  LYS LYS A . n 
B 2 39  ILE 39  35  35  ILE ILE A . n 
B 2 40  ARG 40  36  36  ARG ARG A . n 
B 2 41  LEU 41  37  37  LEU LEU A . n 
B 2 42  ASP 42  38  38  ASP ASP A . n 
B 2 43  THR 43  39  39  THR THR A . n 
B 2 44  GLU 44  40  40  GLU GLU A . n 
B 2 45  THR 45  41  41  THR THR A . n 
B 2 46  GLU 46  42  42  GLU GLU A . n 
B 2 47  GLY 47  43  43  GLY GLY A . n 
B 2 48  VAL 48  44  44  VAL VAL A . n 
B 2 49  PRO 49  45  45  PRO PRO A . n 
B 2 50  SER 50  46  46  SER SER A . n 
B 2 51  THR 51  47  47  THR THR A . n 
B 2 52  ALA 52  48  48  ALA ALA A . n 
B 2 53  ILE 53  49  49  ILE ILE A . n 
B 2 54  ARG 54  50  50  ARG ARG A . n 
B 2 55  GLU 55  51  51  GLU GLU A . n 
B 2 56  ILE 56  52  52  ILE ILE A . n 
B 2 57  SER 57  53  53  SER SER A . n 
B 2 58  LEU 58  54  54  LEU LEU A . n 
B 2 59  LEU 59  55  55  LEU LEU A . n 
B 2 60  LYS 60  56  56  LYS LYS A . n 
B 2 61  GLU 61  57  57  GLU GLU A . n 
B 2 62  LEU 62  58  58  LEU LEU A . n 
B 2 63  ASN 63  59  59  ASN ASN A . n 
B 2 64  HIS 64  60  60  HIS HIS A . n 
B 2 65  PRO 65  61  61  PRO PRO A . n 
B 2 66  ASN 66  62  62  ASN ASN A . n 
B 2 67  ILE 67  63  63  ILE ILE A . n 
B 2 68  VAL 68  64  64  VAL VAL A . n 
B 2 69  LYS 69  65  65  LYS LYS A . n 
B 2 70  LEU 70  66  66  LEU LEU A . n 
B 2 71  LEU 71  67  67  LEU LEU A . n 
B 2 72  ASP 72  68  68  ASP ASP A . n 
B 2 73  VAL 73  69  69  VAL VAL A . n 
B 2 74  ILE 74  70  70  ILE ILE A . n 
B 2 75  HIS 75  71  71  HIS HIS A . n 
B 2 76  THR 76  72  72  THR THR A . n 
B 2 77  GLU 77  73  73  GLU GLU A . n 
B 2 78  ASN 78  74  74  ASN ASN A . n 
B 2 79  LYS 79  75  75  LYS LYS A . n 
B 2 80  LEU 80  76  76  LEU LEU A . n 
B 2 81  TYR 81  77  77  TYR TYR A . n 
B 2 82  LEU 82  78  78  LEU LEU A . n 
B 2 83  VAL 83  79  79  VAL VAL A . n 
B 2 84  PHE 84  80  80  PHE PHE A . n 
B 2 85  GLU 85  81  81  GLU GLU A . n 
B 2 86  PHE 86  82  82  PHE PHE A . n 
B 2 87  LEU 87  83  83  LEU LEU A . n 
B 2 88  HIS 88  84  84  HIS HIS A . n 
B 2 89  GLN 89  85  85  GLN GLN A . n 
B 2 90  ASP 90  86  86  ASP ASP A . n 
B 2 91  LEU 91  87  87  LEU LEU A . n 
B 2 92  LYS 92  88  88  LYS LYS A . n 
B 2 93  LYS 93  89  89  LYS LYS A . n 
B 2 94  PHE 94  90  90  PHE PHE A . n 
B 2 95  MET 95  91  91  MET MET A . n 
B 2 96  ASP 96  92  92  ASP ASP A . n 
B 2 97  ALA 97  93  93  ALA ALA A . n 
B 2 98  SER 98  94  94  SER SER A . n 
B 2 99  ALA 99  95  95  ALA ALA A . n 
B 2 100 LEU 100 96  96  LEU LEU A . n 
B 2 101 THR 101 97  97  THR THR A . n 
B 2 102 GLY 102 98  98  GLY GLY A . n 
B 2 103 ILE 103 99  99  ILE ILE A . n 
B 2 104 PRO 104 100 100 PRO PRO A . n 
B 2 105 LEU 105 101 101 LEU LEU A . n 
B 2 106 PRO 106 102 102 PRO PRO A . n 
B 2 107 LEU 107 103 103 LEU LEU A . n 
B 2 108 ILE 108 104 104 ILE ILE A . n 
B 2 109 LYS 109 105 105 LYS LYS A . n 
B 2 110 SER 110 106 106 SER SER A . n 
B 2 111 TYR 111 107 107 TYR TYR A . n 
B 2 112 LEU 112 108 108 LEU LEU A . n 
B 2 113 PHE 113 109 109 PHE PHE A . n 
B 2 114 GLN 114 110 110 GLN GLN A . n 
B 2 115 LEU 115 111 111 LEU LEU A . n 
B 2 116 LEU 116 112 112 LEU LEU A . n 
B 2 117 GLN 117 113 113 GLN GLN A . n 
B 2 118 GLY 118 114 114 GLY GLY A . n 
B 2 119 LEU 119 115 115 LEU LEU A . n 
B 2 120 ALA 120 116 116 ALA ALA A . n 
B 2 121 PHE 121 117 117 PHE PHE A . n 
B 2 122 CYS 122 118 118 CYS CYS A . n 
B 2 123 HIS 123 119 119 HIS HIS A . n 
B 2 124 SER 124 120 120 SER SER A . n 
B 2 125 HIS 125 121 121 HIS HIS A . n 
B 2 126 ARG 126 122 122 ARG ARG A . n 
B 2 127 VAL 127 123 123 VAL VAL A . n 
B 2 128 LEU 128 124 124 LEU LEU A . n 
B 2 129 HIS 129 125 125 HIS HIS A . n 
B 2 130 ARG 130 126 126 ARG ARG A . n 
B 2 131 ASP 131 127 127 ASP ASP A . n 
B 2 132 LEU 132 128 128 LEU LEU A . n 
B 2 133 LYS 133 129 129 LYS LYS A . n 
B 2 134 PRO 134 130 130 PRO PRO A . n 
B 2 135 GLN 135 131 131 GLN GLN A . n 
B 2 136 ASN 136 132 132 ASN ASN A . n 
B 2 137 LEU 137 133 133 LEU LEU A . n 
B 2 138 LEU 138 134 134 LEU LEU A . n 
B 2 139 ILE 139 135 135 ILE ILE A . n 
B 2 140 ASN 140 136 136 ASN ASN A . n 
B 2 141 THR 141 137 137 THR THR A . n 
B 2 142 GLU 142 138 138 GLU GLU A . n 
B 2 143 GLY 143 139 139 GLY GLY A . n 
B 2 144 ALA 144 140 140 ALA ALA A . n 
B 2 145 ILE 145 141 141 ILE ILE A . n 
B 2 146 LYS 146 142 142 LYS LYS A . n 
B 2 147 LEU 147 143 143 LEU LEU A . n 
B 2 148 ALA 148 144 144 ALA ALA A . n 
B 2 149 ASP 149 145 145 ASP ASP A . n 
B 2 150 PHE 150 146 146 PHE PHE A . n 
B 2 151 GLY 151 147 147 GLY GLY A . n 
B 2 152 LEU 152 148 148 LEU LEU A . n 
B 2 153 ALA 153 149 149 ALA ALA A . n 
B 2 154 ARG 154 150 150 ARG ARG A . n 
B 2 155 ALA 155 151 151 ALA ALA A . n 
B 2 156 PHE 156 152 152 PHE PHE A . n 
B 2 157 GLY 157 153 153 GLY GLY A . n 
B 2 158 VAL 158 154 154 VAL VAL A . n 
B 2 159 PRO 159 155 155 PRO PRO A . n 
B 2 160 VAL 160 156 156 VAL VAL A . n 
B 2 161 ARG 161 157 157 ARG ARG A . n 
B 2 162 THR 162 158 158 THR THR A . n 
B 2 163 TYR 163 159 159 TYR TYR A . n 
B 2 164 TPO 164 160 160 TPO TPO A . n 
B 2 165 HIS 165 161 161 HIS HIS A . n 
B 2 166 GLU 166 162 162 GLU GLU A . n 
B 2 167 VAL 167 163 163 VAL VAL A . n 
B 2 168 VAL 168 164 164 VAL VAL A . n 
B 2 169 THR 169 165 165 THR THR A . n 
B 2 170 LEU 170 166 166 LEU LEU A . n 
B 2 171 TRP 171 167 167 TRP TRP A . n 
B 2 172 TYR 172 168 168 TYR TYR A . n 
B 2 173 ARG 173 169 169 ARG ARG A . n 
B 2 174 ALA 174 170 170 ALA ALA A . n 
B 2 175 PRO 175 171 171 PRO PRO A . n 
B 2 176 GLU 176 172 172 GLU GLU A . n 
B 2 177 ILE 177 173 173 ILE ILE A . n 
B 2 178 LEU 178 174 174 LEU LEU A . n 
B 2 179 LEU 179 175 175 LEU LEU A . n 
B 2 180 GLY 180 176 176 GLY GLY A . n 
B 2 181 CYS 181 177 177 CYS CYS A . n 
B 2 182 LYS 182 178 178 LYS LYS A . n 
B 2 183 TYR 183 179 179 TYR TYR A . n 
B 2 184 TYR 184 180 180 TYR TYR A . n 
B 2 185 SER 185 181 181 SER SER A . n 
B 2 186 THR 186 182 182 THR THR A . n 
B 2 187 ALA 187 183 183 ALA ALA A . n 
B 2 188 VAL 188 184 184 VAL VAL A . n 
B 2 189 ASP 189 185 185 ASP ASP A . n 
B 2 190 ILE 190 186 186 ILE ILE A . n 
B 2 191 TRP 191 187 187 TRP TRP A . n 
B 2 192 SER 192 188 188 SER SER A . n 
B 2 193 LEU 193 189 189 LEU LEU A . n 
B 2 194 GLY 194 190 190 GLY GLY A . n 
B 2 195 CYS 195 191 191 CYS CYS A . n 
B 2 196 ILE 196 192 192 ILE ILE A . n 
B 2 197 PHE 197 193 193 PHE PHE A . n 
B 2 198 ALA 198 194 194 ALA ALA A . n 
B 2 199 GLU 199 195 195 GLU GLU A . n 
B 2 200 MET 200 196 196 MET MET A . n 
B 2 201 VAL 201 197 197 VAL VAL A . n 
B 2 202 THR 202 198 198 THR THR A . n 
B 2 203 ARG 203 199 199 ARG ARG A . n 
B 2 204 ARG 204 200 200 ARG ARG A . n 
B 2 205 ALA 205 201 201 ALA ALA A . n 
B 2 206 LEU 206 202 202 LEU LEU A . n 
B 2 207 PHE 207 203 203 PHE PHE A . n 
B 2 208 PRO 208 204 204 PRO PRO A . n 
B 2 209 GLY 209 205 205 GLY GLY A . n 
B 2 210 ASP 210 206 206 ASP ASP A . n 
B 2 211 SER 211 207 207 SER SER A . n 
B 2 212 GLU 212 208 208 GLU GLU A . n 
B 2 213 ILE 213 209 209 ILE ILE A . n 
B 2 214 ASP 214 210 210 ASP ASP A . n 
B 2 215 GLN 215 211 211 GLN GLN A . n 
B 2 216 LEU 216 212 212 LEU LEU A . n 
B 2 217 PHE 217 213 213 PHE PHE A . n 
B 2 218 ARG 218 214 214 ARG ARG A . n 
B 2 219 ILE 219 215 215 ILE ILE A . n 
B 2 220 PHE 220 216 216 PHE PHE A . n 
B 2 221 ARG 221 217 217 ARG ARG A . n 
B 2 222 THR 222 218 218 THR THR A . n 
B 2 223 LEU 223 219 219 LEU LEU A . n 
B 2 224 GLY 224 220 220 GLY GLY A . n 
B 2 225 THR 225 221 221 THR THR A . n 
B 2 226 PRO 226 222 222 PRO PRO A . n 
B 2 227 ASP 227 223 223 ASP ASP A . n 
B 2 228 GLU 228 224 224 GLU GLU A . n 
B 2 229 VAL 229 225 225 VAL VAL A . n 
B 2 230 VAL 230 226 226 VAL VAL A . n 
B 2 231 TRP 231 227 227 TRP TRP A . n 
B 2 232 PRO 232 228 228 PRO PRO A . n 
B 2 233 GLY 233 229 229 GLY GLY A . n 
B 2 234 VAL 234 230 230 VAL VAL A . n 
B 2 235 THR 235 231 231 THR THR A . n 
B 2 236 SER 236 232 232 SER SER A . n 
B 2 237 MET 237 233 233 MET MET A . n 
B 2 238 PRO 238 234 234 PRO PRO A . n 
B 2 239 ASP 239 235 235 ASP ASP A . n 
B 2 240 TYR 240 236 236 TYR TYR A . n 
B 2 241 LYS 241 237 237 LYS LYS A . n 
B 2 242 PRO 242 238 238 PRO PRO A . n 
B 2 243 SER 243 239 239 SER SER A . n 
B 2 244 PHE 244 240 240 PHE PHE A . n 
B 2 245 PRO 245 241 241 PRO PRO A . n 
B 2 246 LYS 246 242 242 LYS LYS A . n 
B 2 247 TRP 247 243 243 TRP TRP A . n 
B 2 248 ALA 248 244 244 ALA ALA A . n 
B 2 249 ARG 249 245 245 ARG ARG A . n 
B 2 250 GLN 250 246 246 GLN GLN A . n 
B 2 251 ASP 251 247 247 ASP ASP A . n 
B 2 252 PHE 252 248 248 PHE PHE A . n 
B 2 253 SER 253 249 249 SER SER A . n 
B 2 254 LYS 254 250 250 LYS LYS A . n 
B 2 255 VAL 255 251 251 VAL VAL A . n 
B 2 256 VAL 256 252 252 VAL VAL A . n 
B 2 257 PRO 257 253 253 PRO PRO A . n 
B 2 258 PRO 258 254 254 PRO PRO A . n 
B 2 259 LEU 259 255 255 LEU LEU A . n 
B 2 260 ASP 260 256 256 ASP ASP A . n 
B 2 261 GLU 261 257 257 GLU GLU A . n 
B 2 262 ASP 262 258 258 ASP ASP A . n 
B 2 263 GLY 263 259 259 GLY GLY A . n 
B 2 264 ARG 264 260 260 ARG ARG A . n 
B 2 265 SER 265 261 261 SER SER A . n 
B 2 266 LEU 266 262 262 LEU LEU A . n 
B 2 267 LEU 267 263 263 LEU LEU A . n 
B 2 268 SER 268 264 264 SER SER A . n 
B 2 269 GLN 269 265 265 GLN GLN A . n 
B 2 270 MET 270 266 266 MET MET A . n 
B 2 271 LEU 271 267 267 LEU LEU A . n 
B 2 272 HIS 272 268 268 HIS HIS A . n 
B 2 273 TYR 273 269 269 TYR TYR A . n 
B 2 274 ASP 274 270 270 ASP ASP A . n 
B 2 275 PRO 275 271 271 PRO PRO A . n 
B 2 276 ASN 276 272 272 ASN ASN A . n 
B 2 277 LYS 277 273 273 LYS LYS A . n 
B 2 278 ARG 278 274 274 ARG ARG A . n 
B 2 279 ILE 279 275 275 ILE ILE A . n 
B 2 280 SER 280 276 276 SER SER A . n 
B 2 281 ALA 281 277 277 ALA ALA A . n 
B 2 282 LYS 282 278 278 LYS LYS A . n 
B 2 283 ALA 283 279 279 ALA ALA A . n 
B 2 284 ALA 284 280 280 ALA ALA A . n 
B 2 285 LEU 285 281 281 LEU LEU A . n 
B 2 286 ALA 286 282 282 ALA ALA A . n 
B 2 287 HIS 287 283 283 HIS HIS A . n 
B 2 288 PRO 288 284 284 PRO PRO A . n 
B 2 289 PHE 289 285 285 PHE PHE A . n 
B 2 290 PHE 290 286 286 PHE PHE A . n 
B 2 291 GLN 291 287 287 GLN GLN A . n 
B 2 292 ASP 292 288 288 ASP ASP A . n 
B 2 293 VAL 293 289 289 VAL VAL A . n 
B 2 294 THR 294 290 290 THR THR A . n 
B 2 295 LYS 295 291 291 LYS LYS A . n 
B 2 296 PRO 296 292 292 PRO PRO A . n 
B 2 297 VAL 297 293 293 VAL VAL A . n 
B 2 298 PRO 298 294 294 PRO PRO A . n 
B 2 299 HIS 299 295 295 HIS HIS A . n 
B 2 300 LEU 300 296 296 LEU LEU A . n 
B 2 301 ARG 301 297 297 ARG ARG A . n 
B 2 302 LEU 302 298 298 LEU LEU A . n 
C 1 1   GLY 1   171 171 GLY GLY B . n 
C 1 2   VAL 2   172 172 VAL VAL B . n 
C 1 3   ASN 3   173 173 ASN ASN B . n 
C 1 4   GLU 4   174 174 GLU GLU B . n 
C 1 5   VAL 5   175 175 VAL VAL B . n 
C 1 6   PRO 6   176 176 PRO PRO B . n 
C 1 7   ASP 7   177 177 ASP ASP B . n 
C 1 8   TYR 8   178 178 TYR TYR B . n 
C 1 9   HIS 9   179 179 HIS HIS B . n 
C 1 10  GLU 10  180 180 GLU GLU B . n 
C 1 11  ASP 11  181 181 ASP ASP B . n 
C 1 12  ILE 12  182 182 ILE ILE B . n 
C 1 13  HIS 13  183 183 HIS HIS B . n 
C 1 14  THR 14  184 184 THR THR B . n 
C 1 15  TYR 15  185 185 TYR TYR B . n 
C 1 16  LEU 16  186 186 LEU LEU B . n 
C 1 17  ARG 17  187 187 ARG ARG B . n 
C 1 18  GLU 18  188 188 GLU GLU B . n 
C 1 19  MET 19  189 189 MET MET B . n 
C 1 20  GLU 20  190 190 GLU GLU B . n 
C 1 21  VAL 21  191 191 VAL VAL B . n 
C 1 22  LYS 22  192 192 LYS LYS B . n 
C 1 23  CYS 23  193 193 CYS CYS B . n 
C 1 24  LYS 24  194 194 LYS LYS B . n 
C 1 25  PRO 25  195 195 PRO PRO B . n 
C 1 26  LYS 26  196 196 LYS LYS B . n 
C 1 27  VAL 27  197 197 VAL VAL B . n 
C 1 28  GLY 28  198 198 GLY GLY B . n 
C 1 29  TYR 29  199 199 TYR TYR B . n 
C 1 30  MET 30  200 200 MET MET B . n 
C 1 31  LYS 31  201 201 LYS LYS B . n 
C 1 32  LYS 32  202 202 LYS LYS B . n 
C 1 33  GLN 33  203 203 GLN GLN B . n 
C 1 34  PRO 34  204 204 PRO PRO B . n 
C 1 35  ASP 35  205 205 ASP ASP B . n 
C 1 36  ILE 36  206 206 ILE ILE B . n 
C 1 37  THR 37  207 207 THR THR B . n 
C 1 38  ASN 38  208 208 ASN ASN B . n 
C 1 39  SER 39  209 209 SER SER B . n 
C 1 40  MET 40  210 210 MET MET B . n 
C 1 41  ARG 41  211 211 ARG ARG B . n 
C 1 42  ALA 42  212 212 ALA ALA B . n 
C 1 43  ILE 43  213 213 ILE ILE B . n 
C 1 44  LEU 44  214 214 LEU LEU B . n 
C 1 45  VAL 45  215 215 VAL VAL B . n 
C 1 46  ASP 46  216 216 ASP ASP B . n 
C 1 47  TRP 47  217 217 TRP TRP B . n 
C 1 48  LEU 48  218 218 LEU LEU B . n 
C 1 49  VAL 49  219 219 VAL VAL B . n 
C 1 50  GLU 50  220 220 GLU GLU B . n 
C 1 51  VAL 51  221 221 VAL VAL B . n 
C 1 52  GLY 52  222 222 GLY GLY B . n 
C 1 53  GLU 53  223 223 GLU GLU B . n 
C 1 54  GLU 54  224 224 GLU GLU B . n 
C 1 55  TYR 55  225 225 TYR TYR B . n 
C 1 56  LYS 56  226 226 LYS LYS B . n 
C 1 57  LEU 57  227 227 LEU LEU B . n 
C 1 58  GLN 58  228 228 GLN GLN B . n 
C 1 59  ASN 59  229 229 ASN ASN B . n 
C 1 60  GLU 60  230 230 GLU GLU B . n 
C 1 61  THR 61  231 231 THR THR B . n 
C 1 62  LEU 62  232 232 LEU LEU B . n 
C 1 63  HIS 63  233 233 HIS HIS B . n 
C 1 64  LEU 64  234 234 LEU LEU B . n 
C 1 65  ALA 65  235 235 ALA ALA B . n 
C 1 66  VAL 66  236 236 VAL VAL B . n 
C 1 67  ASN 67  237 237 ASN ASN B . n 
C 1 68  TYR 68  238 238 TYR TYR B . n 
C 1 69  ILE 69  239 239 ILE ILE B . n 
C 1 70  ASP 70  240 240 ASP ASP B . n 
C 1 71  ARG 71  241 241 ARG ARG B . n 
C 1 72  PHE 72  242 242 PHE PHE B . n 
C 1 73  LEU 73  243 243 LEU LEU B . n 
C 1 74  SER 74  244 244 SER SER B . n 
C 1 75  SER 75  245 245 SER SER B . n 
C 1 76  MET 76  246 246 MET MET B . n 
C 1 77  SER 77  247 247 SER SER B . n 
C 1 78  VAL 78  248 248 VAL VAL B . n 
C 1 79  LEU 79  249 249 LEU LEU B . n 
C 1 80  ARG 80  250 250 ARG ARG B . n 
C 1 81  GLY 81  251 251 GLY GLY B . n 
C 1 82  LYS 82  252 252 LYS LYS B . n 
C 1 83  LEU 83  253 253 LEU LEU B . n 
C 1 84  GLN 84  254 254 GLN GLN B . n 
C 1 85  LEU 85  255 255 LEU LEU B . n 
C 1 86  VAL 86  256 256 VAL VAL B . n 
C 1 87  GLY 87  257 257 GLY GLY B . n 
C 1 88  THR 88  258 258 THR THR B . n 
C 1 89  ALA 89  259 259 ALA ALA B . n 
C 1 90  ALA 90  260 260 ALA ALA B . n 
C 1 91  MET 91  261 261 MET MET B . n 
C 1 92  LEU 92  262 262 LEU LEU B . n 
C 1 93  LEU 93  263 263 LEU LEU B . n 
C 1 94  ALA 94  264 264 ALA ALA B . n 
C 1 95  SER 95  265 265 SER SER B . n 
C 1 96  LYS 96  266 266 LYS LYS B . n 
C 1 97  PHE 97  267 267 PHE PHE B . n 
C 1 98  GLU 98  268 268 GLU GLU B . n 
C 1 99  GLU 99  269 269 GLU GLU B . n 
C 1 100 ILE 100 270 270 ILE ILE B . n 
C 1 101 TYR 101 271 271 TYR TYR B . n 
C 1 102 PRO 102 272 272 PRO PRO B . n 
C 1 103 PRO 103 273 273 PRO PRO B . n 
C 1 104 GLU 104 274 274 GLU GLU B . n 
C 1 105 VAL 105 275 275 VAL VAL B . n 
C 1 106 ALA 106 276 276 ALA ALA B . n 
C 1 107 GLU 107 277 277 GLU GLU B . n 
C 1 108 PHE 108 278 278 PHE PHE B . n 
C 1 109 VAL 109 279 279 VAL VAL B . n 
C 1 110 TYR 110 280 280 TYR TYR B . n 
C 1 111 ILE 111 281 281 ILE ILE B . n 
C 1 112 THR 112 282 282 THR THR B . n 
C 1 113 ASP 113 283 283 ASP ASP B . n 
C 1 114 ASP 114 284 284 ASP ASP B . n 
C 1 115 THR 115 285 285 THR THR B . n 
C 1 116 TYR 116 286 286 TYR TYR B . n 
C 1 117 THR 117 287 287 THR THR B . n 
C 1 118 LYS 118 288 288 LYS LYS B . n 
C 1 119 LYS 119 289 289 LYS LYS B . n 
C 1 120 GLN 120 290 290 GLN GLN B . n 
C 1 121 VAL 121 291 291 VAL VAL B . n 
C 1 122 LEU 122 292 292 LEU LEU B . n 
C 1 123 ARG 123 293 293 ARG ARG B . n 
C 1 124 MET 124 294 294 MET MET B . n 
C 1 125 GLU 125 295 295 GLU GLU B . n 
C 1 126 HIS 126 296 296 HIS HIS B . n 
C 1 127 LEU 127 297 297 LEU LEU B . n 
C 1 128 VAL 128 298 298 VAL VAL B . n 
C 1 129 LEU 129 299 299 LEU LEU B . n 
C 1 130 LYS 130 300 300 LYS LYS B . n 
C 1 131 VAL 131 301 301 VAL VAL B . n 
C 1 132 LEU 132 302 302 LEU LEU B . n 
C 1 133 ALA 133 303 303 ALA ALA B . n 
C 1 134 PHE 134 304 304 PHE PHE B . n 
C 1 135 ASP 135 305 305 ASP ASP B . n 
C 1 136 LEU 136 306 306 LEU LEU B . n 
C 1 137 ALA 137 307 307 ALA ALA B . n 
C 1 138 ALA 138 308 308 ALA ALA B . n 
C 1 139 PRO 139 309 309 PRO PRO B . n 
C 1 140 THR 140 310 310 THR THR B . n 
C 1 141 ILE 141 311 311 ILE ILE B . n 
C 1 142 ASN 142 312 312 ASN ASN B . n 
C 1 143 GLN 143 313 313 GLN GLN B . n 
C 1 144 PHE 144 314 314 PHE PHE B . n 
C 1 145 LEU 145 315 315 LEU LEU B . n 
C 1 146 THR 146 316 316 THR THR B . n 
C 1 147 GLN 147 317 317 GLN GLN B . n 
C 1 148 TYR 148 318 318 TYR TYR B . n 
C 1 149 PHE 149 319 319 PHE PHE B . n 
C 1 150 LEU 150 320 320 LEU LEU B . n 
C 1 151 HIS 151 321 321 HIS HIS B . n 
C 1 152 GLN 152 322 322 GLN GLN B . n 
C 1 153 GLN 153 323 323 GLN GLN B . n 
C 1 154 PRO 154 324 324 PRO PRO B . n 
C 1 155 ALA 155 325 325 ALA ALA B . n 
C 1 156 ASN 156 326 326 ASN ASN B . n 
C 1 157 CYS 157 327 327 CYS CYS B . n 
C 1 158 LYS 158 328 328 LYS LYS B . n 
C 1 159 VAL 159 329 329 VAL VAL B . n 
C 1 160 GLU 160 330 330 GLU GLU B . n 
C 1 161 SER 161 331 331 SER SER B . n 
C 1 162 LEU 162 332 332 LEU LEU B . n 
C 1 163 ALA 163 333 333 ALA ALA B . n 
C 1 164 MET 164 334 334 MET MET B . n 
C 1 165 PHE 165 335 335 PHE PHE B . n 
C 1 166 LEU 166 336 336 LEU LEU B . n 
C 1 167 GLY 167 337 337 GLY GLY B . n 
C 1 168 GLU 168 338 338 GLU GLU B . n 
C 1 169 LEU 169 339 339 LEU LEU B . n 
C 1 170 SER 170 340 340 SER SER B . n 
C 1 171 LEU 171 341 341 LEU LEU B . n 
C 1 172 ILE 172 342 342 ILE ILE B . n 
C 1 173 ASP 173 343 343 ASP ASP B . n 
C 1 174 ALA 174 344 344 ALA ALA B . n 
C 1 175 ASP 175 345 345 ASP ASP B . n 
C 1 176 PRO 176 346 346 PRO PRO B . n 
C 1 177 TYR 177 347 347 TYR TYR B . n 
C 1 178 LEU 178 348 348 LEU LEU B . n 
C 1 179 LYS 179 349 349 LYS LYS B . n 
C 1 180 TYR 180 350 350 TYR TYR B . n 
C 1 181 LEU 181 351 351 LEU LEU B . n 
C 1 182 PRO 182 352 352 PRO PRO B . n 
C 1 183 SER 183 353 353 SER SER B . n 
C 1 184 VAL 184 354 354 VAL VAL B . n 
C 1 185 ILE 185 355 355 ILE ILE B . n 
C 1 186 ALA 186 356 356 ALA ALA B . n 
C 1 187 ALA 187 357 357 ALA ALA B . n 
C 1 188 ALA 188 358 358 ALA ALA B . n 
C 1 189 ALA 189 359 359 ALA ALA B . n 
C 1 190 PHE 190 360 360 PHE PHE B . n 
C 1 191 HIS 191 361 361 HIS HIS B . n 
C 1 192 LEU 192 362 362 LEU LEU B . n 
C 1 193 ALA 193 363 363 ALA ALA B . n 
C 1 194 LEU 194 364 364 LEU LEU B . n 
C 1 195 TYR 195 365 365 TYR TYR B . n 
C 1 196 THR 196 366 366 THR THR B . n 
C 1 197 VAL 197 367 367 VAL VAL B . n 
C 1 198 THR 198 368 368 THR THR B . n 
C 1 199 GLY 199 369 369 GLY GLY B . n 
C 1 200 GLN 200 370 370 GLN GLN B . n 
C 1 201 SER 201 371 371 SER SER B . n 
C 1 202 TRP 202 372 372 TRP TRP B . n 
C 1 203 PRO 203 373 373 PRO PRO B . n 
C 1 204 GLU 204 374 374 GLU GLU B . n 
C 1 205 SER 205 375 375 SER SER B . n 
C 1 206 LEU 206 376 376 LEU LEU B . n 
C 1 207 VAL 207 377 377 VAL VAL B . n 
C 1 208 GLN 208 378 378 GLN GLN B . n 
C 1 209 LYS 209 379 379 LYS LYS B . n 
C 1 210 THR 210 380 380 THR THR B . n 
C 1 211 GLY 211 381 381 GLY GLY B . n 
C 1 212 TYR 212 382 382 TYR TYR B . n 
C 1 213 THR 213 383 383 THR THR B . n 
C 1 214 LEU 214 384 384 LEU LEU B . n 
C 1 215 GLU 215 385 385 GLU GLU B . n 
C 1 216 THR 216 386 386 THR THR B . n 
C 1 217 LEU 217 387 387 LEU LEU B . n 
C 1 218 LYS 218 388 388 LYS LYS B . n 
C 1 219 PRO 219 389 389 PRO PRO B . n 
C 1 220 CYS 220 390 390 CYS CYS B . n 
C 1 221 LEU 221 391 391 LEU LEU B . n 
C 1 222 LEU 222 392 392 LEU LEU B . n 
C 1 223 ASP 223 393 393 ASP ASP B . n 
C 1 224 LEU 224 394 394 LEU LEU B . n 
C 1 225 HIS 225 395 395 HIS HIS B . n 
C 1 226 GLN 226 396 396 GLN GLN B . n 
C 1 227 THR 227 397 397 THR THR B . n 
C 1 228 TYR 228 398 398 TYR TYR B . n 
C 1 229 LEU 229 399 399 LEU LEU B . n 
C 1 230 ARG 230 400 400 ARG ARG B . n 
C 1 231 ALA 231 401 401 ALA ALA B . n 
C 1 232 PRO 232 402 402 PRO PRO B . n 
C 1 233 GLN 233 403 403 GLN GLN B . n 
C 1 234 HIS 234 404 404 HIS HIS B . n 
C 1 235 ALA 235 405 405 ALA ALA B . n 
C 1 236 GLN 236 406 406 GLN GLN B . n 
C 1 237 GLN 237 407 407 GLN GLN B . n 
C 1 238 SER 238 408 408 SER SER B . n 
C 1 239 ILE 239 409 409 ILE ILE B . n 
C 1 240 ARG 240 410 410 ARG ARG B . n 
C 1 241 GLU 241 411 411 GLU GLU B . n 
C 1 242 LYS 242 412 412 LYS LYS B . n 
C 1 243 TYR 243 413 413 TYR TYR B . n 
C 1 244 LYS 244 414 414 LYS LYS B . n 
C 1 245 ASN 245 415 415 ASN ASN B . n 
C 1 246 SER 246 416 416 SER SER B . n 
C 1 247 LYS 247 417 417 LYS LYS B . n 
C 1 248 TYR 248 418 418 TYR TYR B . n 
C 1 249 HIS 249 419 419 HIS HIS B . n 
C 1 250 GLY 250 420 420 GLY GLY B . n 
C 1 251 VAL 251 421 421 VAL VAL B . n 
C 1 252 SER 252 422 422 SER SER B . n 
C 1 253 LEU 253 423 423 LEU LEU B . n 
C 1 254 LEU 254 424 424 LEU LEU B . n 
C 1 255 ASN 255 425 425 ASN ASN B . n 
C 1 256 PRO 256 426 426 PRO PRO B . n 
C 1 257 PRO 257 427 427 PRO PRO B . n 
C 1 258 GLU 258 428 428 GLU GLU B . n 
C 1 259 THR 259 429 429 THR THR B . n 
C 1 260 LEU 260 430 430 LEU LEU B . n 
C 1 261 ASN 261 431 431 ASN ASN B . n 
C 1 262 VAL 262 432 432 VAL VAL B . n 
C 1 263 HIS 263 433 433 HIS HIS B . n 
C 1 264 HIS 264 434 434 HIS HIS B . n 
C 1 265 HIS 265 435 435 HIS HIS B . n 
C 1 266 HIS 266 436 436 HIS HIS B . n 
C 1 267 HIS 267 437 437 HIS HIS B . n 
C 1 268 HIS 268 438 438 HIS HIS B . n 
D 2 1   GLY 1   -3  ?   ?   ?   C . n 
D 2 2   PRO 2   -2  ?   ?   ?   C . n 
D 2 3   GLY 3   -1  ?   ?   ?   C . n 
D 2 4   SER 4   0   0   SER SER C . n 
D 2 5   MET 5   1   1   MET MET C . n 
D 2 6   GLU 6   2   2   GLU GLU C . n 
D 2 7   ASN 7   3   3   ASN ASN C . n 
D 2 8   PHE 8   4   4   PHE PHE C . n 
D 2 9   GLN 9   5   5   GLN GLN C . n 
D 2 10  LYS 10  6   6   LYS LYS C . n 
D 2 11  VAL 11  7   7   VAL VAL C . n 
D 2 12  GLU 12  8   8   GLU GLU C . n 
D 2 13  LYS 13  9   9   LYS LYS C . n 
D 2 14  ILE 14  10  10  ILE ILE C . n 
D 2 15  GLY 15  11  11  GLY GLY C . n 
D 2 16  GLU 16  12  12  GLU GLU C . n 
D 2 17  GLY 17  13  13  GLY GLY C . n 
D 2 18  THR 18  14  14  THR THR C . n 
D 2 19  TYR 19  15  15  TYR TYR C . n 
D 2 20  GLY 20  16  16  GLY GLY C . n 
D 2 21  VAL 21  17  17  VAL VAL C . n 
D 2 22  VAL 22  18  18  VAL VAL C . n 
D 2 23  TYR 23  19  19  TYR TYR C . n 
D 2 24  LYS 24  20  20  LYS LYS C . n 
D 2 25  ALA 25  21  21  ALA ALA C . n 
D 2 26  ARG 26  22  22  ARG ARG C . n 
D 2 27  ASN 27  23  23  ASN ASN C . n 
D 2 28  LYS 28  24  24  LYS LYS C . n 
D 2 29  LEU 29  25  25  LEU LEU C . n 
D 2 30  THR 30  26  26  THR THR C . n 
D 2 31  GLY 31  27  27  GLY GLY C . n 
D 2 32  GLU 32  28  28  GLU GLU C . n 
D 2 33  VAL 33  29  29  VAL VAL C . n 
D 2 34  VAL 34  30  30  VAL VAL C . n 
D 2 35  ALA 35  31  31  ALA ALA C . n 
D 2 36  LEU 36  32  32  LEU LEU C . n 
D 2 37  LYS 37  33  33  LYS LYS C . n 
D 2 38  LYS 38  34  34  LYS LYS C . n 
D 2 39  ILE 39  35  35  ILE ILE C . n 
D 2 40  ARG 40  36  36  ARG ARG C . n 
D 2 41  LEU 41  37  37  LEU LEU C . n 
D 2 42  ASP 42  38  38  ASP ASP C . n 
D 2 43  THR 43  39  39  THR THR C . n 
D 2 44  GLU 44  40  40  GLU GLU C . n 
D 2 45  THR 45  41  41  THR THR C . n 
D 2 46  GLU 46  42  42  GLU GLU C . n 
D 2 47  GLY 47  43  43  GLY GLY C . n 
D 2 48  VAL 48  44  44  VAL VAL C . n 
D 2 49  PRO 49  45  45  PRO PRO C . n 
D 2 50  SER 50  46  46  SER SER C . n 
D 2 51  THR 51  47  47  THR THR C . n 
D 2 52  ALA 52  48  48  ALA ALA C . n 
D 2 53  ILE 53  49  49  ILE ILE C . n 
D 2 54  ARG 54  50  50  ARG ARG C . n 
D 2 55  GLU 55  51  51  GLU GLU C . n 
D 2 56  ILE 56  52  52  ILE ILE C . n 
D 2 57  SER 57  53  53  SER SER C . n 
D 2 58  LEU 58  54  54  LEU LEU C . n 
D 2 59  LEU 59  55  55  LEU LEU C . n 
D 2 60  LYS 60  56  56  LYS LYS C . n 
D 2 61  GLU 61  57  57  GLU GLU C . n 
D 2 62  LEU 62  58  58  LEU LEU C . n 
D 2 63  ASN 63  59  59  ASN ASN C . n 
D 2 64  HIS 64  60  60  HIS HIS C . n 
D 2 65  PRO 65  61  61  PRO PRO C . n 
D 2 66  ASN 66  62  62  ASN ASN C . n 
D 2 67  ILE 67  63  63  ILE ILE C . n 
D 2 68  VAL 68  64  64  VAL VAL C . n 
D 2 69  LYS 69  65  65  LYS LYS C . n 
D 2 70  LEU 70  66  66  LEU LEU C . n 
D 2 71  LEU 71  67  67  LEU LEU C . n 
D 2 72  ASP 72  68  68  ASP ASP C . n 
D 2 73  VAL 73  69  69  VAL VAL C . n 
D 2 74  ILE 74  70  70  ILE ILE C . n 
D 2 75  HIS 75  71  71  HIS HIS C . n 
D 2 76  THR 76  72  72  THR THR C . n 
D 2 77  GLU 77  73  73  GLU GLU C . n 
D 2 78  ASN 78  74  74  ASN ASN C . n 
D 2 79  LYS 79  75  75  LYS LYS C . n 
D 2 80  LEU 80  76  76  LEU LEU C . n 
D 2 81  TYR 81  77  77  TYR TYR C . n 
D 2 82  LEU 82  78  78  LEU LEU C . n 
D 2 83  VAL 83  79  79  VAL VAL C . n 
D 2 84  PHE 84  80  80  PHE PHE C . n 
D 2 85  GLU 85  81  81  GLU GLU C . n 
D 2 86  PHE 86  82  82  PHE PHE C . n 
D 2 87  LEU 87  83  83  LEU LEU C . n 
D 2 88  HIS 88  84  84  HIS HIS C . n 
D 2 89  GLN 89  85  85  GLN GLN C . n 
D 2 90  ASP 90  86  86  ASP ASP C . n 
D 2 91  LEU 91  87  87  LEU LEU C . n 
D 2 92  LYS 92  88  88  LYS LYS C . n 
D 2 93  LYS 93  89  89  LYS LYS C . n 
D 2 94  PHE 94  90  90  PHE PHE C . n 
D 2 95  MET 95  91  91  MET MET C . n 
D 2 96  ASP 96  92  92  ASP ASP C . n 
D 2 97  ALA 97  93  93  ALA ALA C . n 
D 2 98  SER 98  94  94  SER SER C . n 
D 2 99  ALA 99  95  95  ALA ALA C . n 
D 2 100 LEU 100 96  96  LEU LEU C . n 
D 2 101 THR 101 97  97  THR THR C . n 
D 2 102 GLY 102 98  98  GLY GLY C . n 
D 2 103 ILE 103 99  99  ILE ILE C . n 
D 2 104 PRO 104 100 100 PRO PRO C . n 
D 2 105 LEU 105 101 101 LEU LEU C . n 
D 2 106 PRO 106 102 102 PRO PRO C . n 
D 2 107 LEU 107 103 103 LEU LEU C . n 
D 2 108 ILE 108 104 104 ILE ILE C . n 
D 2 109 LYS 109 105 105 LYS LYS C . n 
D 2 110 SER 110 106 106 SER SER C . n 
D 2 111 TYR 111 107 107 TYR TYR C . n 
D 2 112 LEU 112 108 108 LEU LEU C . n 
D 2 113 PHE 113 109 109 PHE PHE C . n 
D 2 114 GLN 114 110 110 GLN GLN C . n 
D 2 115 LEU 115 111 111 LEU LEU C . n 
D 2 116 LEU 116 112 112 LEU LEU C . n 
D 2 117 GLN 117 113 113 GLN GLN C . n 
D 2 118 GLY 118 114 114 GLY GLY C . n 
D 2 119 LEU 119 115 115 LEU LEU C . n 
D 2 120 ALA 120 116 116 ALA ALA C . n 
D 2 121 PHE 121 117 117 PHE PHE C . n 
D 2 122 CYS 122 118 118 CYS CYS C . n 
D 2 123 HIS 123 119 119 HIS HIS C . n 
D 2 124 SER 124 120 120 SER SER C . n 
D 2 125 HIS 125 121 121 HIS HIS C . n 
D 2 126 ARG 126 122 122 ARG ARG C . n 
D 2 127 VAL 127 123 123 VAL VAL C . n 
D 2 128 LEU 128 124 124 LEU LEU C . n 
D 2 129 HIS 129 125 125 HIS HIS C . n 
D 2 130 ARG 130 126 126 ARG ARG C . n 
D 2 131 ASP 131 127 127 ASP ASP C . n 
D 2 132 LEU 132 128 128 LEU LEU C . n 
D 2 133 LYS 133 129 129 LYS LYS C . n 
D 2 134 PRO 134 130 130 PRO PRO C . n 
D 2 135 GLN 135 131 131 GLN GLN C . n 
D 2 136 ASN 136 132 132 ASN ASN C . n 
D 2 137 LEU 137 133 133 LEU LEU C . n 
D 2 138 LEU 138 134 134 LEU LEU C . n 
D 2 139 ILE 139 135 135 ILE ILE C . n 
D 2 140 ASN 140 136 136 ASN ASN C . n 
D 2 141 THR 141 137 137 THR THR C . n 
D 2 142 GLU 142 138 138 GLU GLU C . n 
D 2 143 GLY 143 139 139 GLY GLY C . n 
D 2 144 ALA 144 140 140 ALA ALA C . n 
D 2 145 ILE 145 141 141 ILE ILE C . n 
D 2 146 LYS 146 142 142 LYS LYS C . n 
D 2 147 LEU 147 143 143 LEU LEU C . n 
D 2 148 ALA 148 144 144 ALA ALA C . n 
D 2 149 ASP 149 145 145 ASP ASP C . n 
D 2 150 PHE 150 146 146 PHE PHE C . n 
D 2 151 GLY 151 147 147 GLY GLY C . n 
D 2 152 LEU 152 148 148 LEU LEU C . n 
D 2 153 ALA 153 149 149 ALA ALA C . n 
D 2 154 ARG 154 150 150 ARG ARG C . n 
D 2 155 ALA 155 151 151 ALA ALA C . n 
D 2 156 PHE 156 152 152 PHE PHE C . n 
D 2 157 GLY 157 153 153 GLY GLY C . n 
D 2 158 VAL 158 154 154 VAL VAL C . n 
D 2 159 PRO 159 155 155 PRO PRO C . n 
D 2 160 VAL 160 156 156 VAL VAL C . n 
D 2 161 ARG 161 157 157 ARG ARG C . n 
D 2 162 THR 162 158 158 THR THR C . n 
D 2 163 TYR 163 159 159 TYR TYR C . n 
D 2 164 TPO 164 160 160 TPO TPO C . n 
D 2 165 HIS 165 161 161 HIS HIS C . n 
D 2 166 GLU 166 162 162 GLU GLU C . n 
D 2 167 VAL 167 163 163 VAL VAL C . n 
D 2 168 VAL 168 164 164 VAL VAL C . n 
D 2 169 THR 169 165 165 THR THR C . n 
D 2 170 LEU 170 166 166 LEU LEU C . n 
D 2 171 TRP 171 167 167 TRP TRP C . n 
D 2 172 TYR 172 168 168 TYR TYR C . n 
D 2 173 ARG 173 169 169 ARG ARG C . n 
D 2 174 ALA 174 170 170 ALA ALA C . n 
D 2 175 PRO 175 171 171 PRO PRO C . n 
D 2 176 GLU 176 172 172 GLU GLU C . n 
D 2 177 ILE 177 173 173 ILE ILE C . n 
D 2 178 LEU 178 174 174 LEU LEU C . n 
D 2 179 LEU 179 175 175 LEU LEU C . n 
D 2 180 GLY 180 176 176 GLY GLY C . n 
D 2 181 CYS 181 177 177 CYS CYS C . n 
D 2 182 LYS 182 178 178 LYS LYS C . n 
D 2 183 TYR 183 179 179 TYR TYR C . n 
D 2 184 TYR 184 180 180 TYR TYR C . n 
D 2 185 SER 185 181 181 SER SER C . n 
D 2 186 THR 186 182 182 THR THR C . n 
D 2 187 ALA 187 183 183 ALA ALA C . n 
D 2 188 VAL 188 184 184 VAL VAL C . n 
D 2 189 ASP 189 185 185 ASP ASP C . n 
D 2 190 ILE 190 186 186 ILE ILE C . n 
D 2 191 TRP 191 187 187 TRP TRP C . n 
D 2 192 SER 192 188 188 SER SER C . n 
D 2 193 LEU 193 189 189 LEU LEU C . n 
D 2 194 GLY 194 190 190 GLY GLY C . n 
D 2 195 CYS 195 191 191 CYS CYS C . n 
D 2 196 ILE 196 192 192 ILE ILE C . n 
D 2 197 PHE 197 193 193 PHE PHE C . n 
D 2 198 ALA 198 194 194 ALA ALA C . n 
D 2 199 GLU 199 195 195 GLU GLU C . n 
D 2 200 MET 200 196 196 MET MET C . n 
D 2 201 VAL 201 197 197 VAL VAL C . n 
D 2 202 THR 202 198 198 THR THR C . n 
D 2 203 ARG 203 199 199 ARG ARG C . n 
D 2 204 ARG 204 200 200 ARG ARG C . n 
D 2 205 ALA 205 201 201 ALA ALA C . n 
D 2 206 LEU 206 202 202 LEU LEU C . n 
D 2 207 PHE 207 203 203 PHE PHE C . n 
D 2 208 PRO 208 204 204 PRO PRO C . n 
D 2 209 GLY 209 205 205 GLY GLY C . n 
D 2 210 ASP 210 206 206 ASP ASP C . n 
D 2 211 SER 211 207 207 SER SER C . n 
D 2 212 GLU 212 208 208 GLU GLU C . n 
D 2 213 ILE 213 209 209 ILE ILE C . n 
D 2 214 ASP 214 210 210 ASP ASP C . n 
D 2 215 GLN 215 211 211 GLN GLN C . n 
D 2 216 LEU 216 212 212 LEU LEU C . n 
D 2 217 PHE 217 213 213 PHE PHE C . n 
D 2 218 ARG 218 214 214 ARG ARG C . n 
D 2 219 ILE 219 215 215 ILE ILE C . n 
D 2 220 PHE 220 216 216 PHE PHE C . n 
D 2 221 ARG 221 217 217 ARG ARG C . n 
D 2 222 THR 222 218 218 THR THR C . n 
D 2 223 LEU 223 219 219 LEU LEU C . n 
D 2 224 GLY 224 220 220 GLY GLY C . n 
D 2 225 THR 225 221 221 THR THR C . n 
D 2 226 PRO 226 222 222 PRO PRO C . n 
D 2 227 ASP 227 223 223 ASP ASP C . n 
D 2 228 GLU 228 224 224 GLU GLU C . n 
D 2 229 VAL 229 225 225 VAL VAL C . n 
D 2 230 VAL 230 226 226 VAL VAL C . n 
D 2 231 TRP 231 227 227 TRP TRP C . n 
D 2 232 PRO 232 228 228 PRO PRO C . n 
D 2 233 GLY 233 229 229 GLY GLY C . n 
D 2 234 VAL 234 230 230 VAL VAL C . n 
D 2 235 THR 235 231 231 THR THR C . n 
D 2 236 SER 236 232 232 SER SER C . n 
D 2 237 MET 237 233 233 MET MET C . n 
D 2 238 PRO 238 234 234 PRO PRO C . n 
D 2 239 ASP 239 235 235 ASP ASP C . n 
D 2 240 TYR 240 236 236 TYR TYR C . n 
D 2 241 LYS 241 237 237 LYS LYS C . n 
D 2 242 PRO 242 238 238 PRO PRO C . n 
D 2 243 SER 243 239 239 SER SER C . n 
D 2 244 PHE 244 240 240 PHE PHE C . n 
D 2 245 PRO 245 241 241 PRO PRO C . n 
D 2 246 LYS 246 242 ?   ?   ?   C . n 
D 2 247 TRP 247 243 ?   ?   ?   C . n 
D 2 248 ALA 248 244 ?   ?   ?   C . n 
D 2 249 ARG 249 245 ?   ?   ?   C . n 
D 2 250 GLN 250 246 ?   ?   ?   C . n 
D 2 251 ASP 251 247 ?   ?   ?   C . n 
D 2 252 PHE 252 248 ?   ?   ?   C . n 
D 2 253 SER 253 249 ?   ?   ?   C . n 
D 2 254 LYS 254 250 ?   ?   ?   C . n 
D 2 255 VAL 255 251 ?   ?   ?   C . n 
D 2 256 VAL 256 252 ?   ?   ?   C . n 
D 2 257 PRO 257 253 ?   ?   ?   C . n 
D 2 258 PRO 258 254 254 PRO PRO C . n 
D 2 259 LEU 259 255 255 LEU LEU C . n 
D 2 260 ASP 260 256 256 ASP ASP C . n 
D 2 261 GLU 261 257 257 GLU GLU C . n 
D 2 262 ASP 262 258 258 ASP ASP C . n 
D 2 263 GLY 263 259 259 GLY GLY C . n 
D 2 264 ARG 264 260 260 ARG ARG C . n 
D 2 265 SER 265 261 261 SER SER C . n 
D 2 266 LEU 266 262 262 LEU LEU C . n 
D 2 267 LEU 267 263 263 LEU LEU C . n 
D 2 268 SER 268 264 264 SER SER C . n 
D 2 269 GLN 269 265 265 GLN GLN C . n 
D 2 270 MET 270 266 266 MET MET C . n 
D 2 271 LEU 271 267 267 LEU LEU C . n 
D 2 272 HIS 272 268 268 HIS HIS C . n 
D 2 273 TYR 273 269 269 TYR TYR C . n 
D 2 274 ASP 274 270 270 ASP ASP C . n 
D 2 275 PRO 275 271 271 PRO PRO C . n 
D 2 276 ASN 276 272 272 ASN ASN C . n 
D 2 277 LYS 277 273 273 LYS LYS C . n 
D 2 278 ARG 278 274 274 ARG ARG C . n 
D 2 279 ILE 279 275 275 ILE ILE C . n 
D 2 280 SER 280 276 276 SER SER C . n 
D 2 281 ALA 281 277 277 ALA ALA C . n 
D 2 282 LYS 282 278 278 LYS LYS C . n 
D 2 283 ALA 283 279 279 ALA ALA C . n 
D 2 284 ALA 284 280 280 ALA ALA C . n 
D 2 285 LEU 285 281 281 LEU LEU C . n 
D 2 286 ALA 286 282 282 ALA ALA C . n 
D 2 287 HIS 287 283 283 HIS HIS C . n 
D 2 288 PRO 288 284 284 PRO PRO C . n 
D 2 289 PHE 289 285 285 PHE PHE C . n 
D 2 290 PHE 290 286 286 PHE PHE C . n 
D 2 291 GLN 291 287 287 GLN GLN C . n 
D 2 292 ASP 292 288 288 ASP ASP C . n 
D 2 293 VAL 293 289 289 VAL VAL C . n 
D 2 294 THR 294 290 290 THR THR C . n 
D 2 295 LYS 295 291 291 LYS LYS C . n 
D 2 296 PRO 296 292 292 PRO PRO C . n 
D 2 297 VAL 297 293 293 VAL VAL C . n 
D 2 298 PRO 298 294 294 PRO PRO C . n 
D 2 299 HIS 299 295 295 HIS HIS C . n 
D 2 300 LEU 300 296 296 LEU LEU C . n 
D 2 301 ARG 301 297 ?   ?   ?   C . n 
D 2 302 LEU 302 298 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        PYZ 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   PYZ 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 PYZ 1  501 604  PYZ DRG D . 
F 3 PYZ 1  601 601  PYZ DRG A . 
G 3 PYZ 1  602 602  PYZ DRG A . 
H 3 PYZ 1  604 607  PYZ DRG A . 
I 3 PYZ 1  606 801  PYZ DRG A . 
J 3 PYZ 1  501 1605 PYZ DRG B . 
K 3 PYZ 1  502 1606 PYZ DRG B . 
L 3 PYZ 1  503 1701 PYZ DRG B . 
M 3 PYZ 1  504 1801 PYZ DRG B . 
N 3 PYZ 1  501 501  PYZ DRG C . 
O 3 PYZ 1  502 608  PYZ DRG C . 
P 3 PYZ 1  504 1601 PYZ DRG C . 
Q 4 EPE 1  505 1701 EPE EPE C . 
R 5 HOH 1  601 521  HOH HOH D . 
R 5 HOH 2  602 46   HOH HOH D . 
R 5 HOH 3  603 511  HOH HOH D . 
R 5 HOH 4  604 512  HOH HOH D . 
R 5 HOH 5  605 519  HOH HOH D . 
R 5 HOH 6  606 532  HOH HOH D . 
R 5 HOH 7  607 505  HOH HOH D . 
R 5 HOH 8  608 515  HOH HOH D . 
R 5 HOH 9  609 503  HOH HOH D . 
R 5 HOH 10 610 539  HOH HOH D . 
R 5 HOH 11 611 523  HOH HOH D . 
R 5 HOH 12 612 20   HOH HOH D . 
R 5 HOH 13 613 524  HOH HOH D . 
R 5 HOH 14 614 529  HOH HOH D . 
R 5 HOH 15 615 526  HOH HOH D . 
R 5 HOH 16 616 513  HOH HOH D . 
R 5 HOH 17 617 520  HOH HOH D . 
R 5 HOH 18 618 536  HOH HOH D . 
R 5 HOH 19 619 506  HOH HOH D . 
R 5 HOH 20 620 65   HOH HOH D . 
R 5 HOH 21 621 502  HOH HOH D . 
R 5 HOH 22 622 534  HOH HOH D . 
R 5 HOH 23 623 562  HOH HOH D . 
R 5 HOH 24 624 507  HOH HOH D . 
R 5 HOH 25 625 527  HOH HOH D . 
R 5 HOH 26 626 542  HOH HOH D . 
R 5 HOH 27 627 548  HOH HOH D . 
R 5 HOH 28 628 41   HOH HOH D . 
R 5 HOH 29 629 530  HOH HOH D . 
R 5 HOH 30 630 576  HOH HOH D . 
R 5 HOH 31 631 550  HOH HOH D . 
R 5 HOH 32 632 553  HOH HOH D . 
R 5 HOH 33 633 544  HOH HOH D . 
R 5 HOH 34 634 453  HOH HOH D . 
R 5 HOH 35 635 62   HOH HOH D . 
R 5 HOH 36 636 504  HOH HOH D . 
R 5 HOH 37 637 541  HOH HOH D . 
R 5 HOH 38 638 574  HOH HOH D . 
R 5 HOH 39 639 566  HOH HOH D . 
R 5 HOH 40 640 435  HOH HOH D . 
R 5 HOH 41 641 538  HOH HOH D . 
R 5 HOH 42 642 572  HOH HOH D . 
R 5 HOH 43 643 577  HOH HOH D . 
R 5 HOH 44 644 546  HOH HOH D . 
R 5 HOH 45 645 551  HOH HOH D . 
R 5 HOH 46 646 575  HOH HOH D . 
R 5 HOH 47 647 579  HOH HOH D . 
S 5 HOH 1  701 468  HOH HOH A . 
S 5 HOH 2  702 467  HOH HOH A . 
S 5 HOH 3  703 421  HOH HOH A . 
S 5 HOH 4  704 440  HOH HOH A . 
S 5 HOH 5  705 544  HOH HOH A . 
S 5 HOH 6  706 428  HOH HOH A . 
S 5 HOH 7  707 64   HOH HOH A . 
S 5 HOH 8  708 452  HOH HOH A . 
S 5 HOH 9  709 49   HOH HOH A . 
S 5 HOH 10 710 444  HOH HOH A . 
S 5 HOH 11 711 463  HOH HOH A . 
S 5 HOH 12 712 456  HOH HOH A . 
S 5 HOH 13 713 474  HOH HOH A . 
S 5 HOH 14 714 514  HOH HOH A . 
S 5 HOH 15 715 422  HOH HOH A . 
S 5 HOH 16 716 427  HOH HOH A . 
S 5 HOH 17 717 478  HOH HOH A . 
S 5 HOH 18 718 479  HOH HOH A . 
S 5 HOH 19 719 459  HOH HOH A . 
S 5 HOH 20 720 493  HOH HOH A . 
S 5 HOH 21 721 504  HOH HOH A . 
S 5 HOH 22 722 22   HOH HOH A . 
S 5 HOH 23 723 465  HOH HOH A . 
S 5 HOH 24 724 490  HOH HOH A . 
S 5 HOH 25 725 470  HOH HOH A . 
S 5 HOH 26 726 556  HOH HOH A . 
S 5 HOH 27 727 545  HOH HOH A . 
S 5 HOH 28 728 464  HOH HOH A . 
S 5 HOH 29 729 517  HOH HOH A . 
S 5 HOH 30 730 622  HOH HOH A . 
S 5 HOH 31 731 560  HOH HOH A . 
S 5 HOH 32 732 475  HOH HOH A . 
S 5 HOH 33 733 461  HOH HOH A . 
S 5 HOH 34 734 451  HOH HOH A . 
S 5 HOH 35 735 441  HOH HOH A . 
S 5 HOH 36 736 584  HOH HOH A . 
S 5 HOH 37 737 56   HOH HOH A . 
S 5 HOH 38 738 511  HOH HOH A . 
S 5 HOH 39 739 469  HOH HOH A . 
S 5 HOH 40 740 510  HOH HOH A . 
S 5 HOH 41 741 482  HOH HOH A . 
S 5 HOH 42 742 462  HOH HOH A . 
S 5 HOH 43 743 491  HOH HOH A . 
S 5 HOH 44 744 71   HOH HOH A . 
S 5 HOH 45 745 67   HOH HOH A . 
S 5 HOH 46 746 566  HOH HOH A . 
S 5 HOH 47 747 541  HOH HOH A . 
S 5 HOH 48 748 531  HOH HOH A . 
S 5 HOH 49 749 526  HOH HOH A . 
S 5 HOH 50 750 524  HOH HOH A . 
S 5 HOH 51 751 416  HOH HOH A . 
S 5 HOH 52 752 503  HOH HOH A . 
S 5 HOH 53 753 537  HOH HOH A . 
S 5 HOH 54 754 54   HOH HOH A . 
S 5 HOH 55 755 512  HOH HOH A . 
S 5 HOH 56 756 527  HOH HOH A . 
S 5 HOH 57 757 447  HOH HOH A . 
S 5 HOH 58 758 581  HOH HOH A . 
S 5 HOH 59 759 12   HOH HOH A . 
S 5 HOH 60 760 477  HOH HOH A . 
S 5 HOH 61 761 442  HOH HOH A . 
S 5 HOH 62 762 485  HOH HOH A . 
S 5 HOH 63 763 487  HOH HOH A . 
S 5 HOH 64 764 424  HOH HOH A . 
S 5 HOH 65 765 569  HOH HOH A . 
S 5 HOH 66 766 50   HOH HOH A . 
S 5 HOH 67 767 571  HOH HOH A . 
S 5 HOH 68 768 466  HOH HOH A . 
S 5 HOH 69 769 500  HOH HOH A . 
S 5 HOH 70 770 499  HOH HOH A . 
S 5 HOH 71 771 577  HOH HOH A . 
S 5 HOH 72 772 48   HOH HOH A . 
S 5 HOH 73 773 653  HOH HOH A . 
S 5 HOH 74 774 545  HOH HOH A . 
S 5 HOH 75 775 429  HOH HOH A . 
S 5 HOH 76 776 570  HOH HOH A . 
S 5 HOH 77 777 535  HOH HOH A . 
S 5 HOH 78 778 508  HOH HOH A . 
S 5 HOH 79 779 552  HOH HOH A . 
S 5 HOH 80 780 52   HOH HOH A . 
S 5 HOH 81 781 567  HOH HOH A . 
S 5 HOH 82 782 437  HOH HOH A . 
S 5 HOH 83 783 592  HOH HOH A . 
S 5 HOH 84 784 557  HOH HOH A . 
S 5 HOH 85 785 582  HOH HOH A . 
T 5 HOH 1  601 524  HOH HOH B . 
T 5 HOH 2  602 58   HOH HOH B . 
T 5 HOH 3  603 508  HOH HOH B . 
T 5 HOH 4  604 572  HOH HOH B . 
T 5 HOH 5  605 522  HOH HOH B . 
T 5 HOH 6  606 57   HOH HOH B . 
T 5 HOH 7  607 60   HOH HOH B . 
T 5 HOH 8  608 555  HOH HOH B . 
T 5 HOH 9  609 68   HOH HOH B . 
T 5 HOH 10 610 560  HOH HOH B . 
T 5 HOH 11 611 520  HOH HOH B . 
T 5 HOH 12 612 30   HOH HOH B . 
T 5 HOH 13 613 589  HOH HOH B . 
T 5 HOH 14 614 506  HOH HOH B . 
T 5 HOH 15 615 66   HOH HOH B . 
T 5 HOH 16 616 615  HOH HOH B . 
T 5 HOH 17 617 537  HOH HOH B . 
T 5 HOH 18 618 576  HOH HOH B . 
T 5 HOH 19 619 585  HOH HOH B . 
T 5 HOH 20 620 532  HOH HOH B . 
T 5 HOH 21 621 595  HOH HOH B . 
T 5 HOH 22 622 568  HOH HOH B . 
T 5 HOH 23 623 628  HOH HOH B . 
T 5 HOH 24 624 526  HOH HOH B . 
T 5 HOH 25 625 592  HOH HOH B . 
T 5 HOH 26 626 571  HOH HOH B . 
T 5 HOH 27 627 599  HOH HOH B . 
T 5 HOH 28 628 563  HOH HOH B . 
T 5 HOH 29 629 591  HOH HOH B . 
T 5 HOH 30 630 617  HOH HOH B . 
T 5 HOH 31 631 582  HOH HOH B . 
T 5 HOH 32 632 605  HOH HOH B . 
T 5 HOH 33 633 607  HOH HOH B . 
T 5 HOH 34 634 70   HOH HOH B . 
T 5 HOH 35 635 583  HOH HOH B . 
T 5 HOH 36 636 643  HOH HOH B . 
T 5 HOH 37 637 415  HOH HOH B . 
T 5 HOH 38 638 546  HOH HOH B . 
T 5 HOH 39 639 574  HOH HOH B . 
T 5 HOH 40 640 543  HOH HOH B . 
T 5 HOH 41 641 629  HOH HOH B . 
T 5 HOH 42 642 667  HOH HOH B . 
T 5 HOH 43 643 25   HOH HOH B . 
T 5 HOH 44 644 636  HOH HOH B . 
T 5 HOH 45 645 550  HOH HOH B . 
T 5 HOH 46 646 590  HOH HOH B . 
T 5 HOH 47 647 535  HOH HOH B . 
T 5 HOH 48 648 627  HOH HOH B . 
T 5 HOH 49 649 600  HOH HOH B . 
T 5 HOH 50 650 63   HOH HOH B . 
T 5 HOH 51 651 623  HOH HOH B . 
T 5 HOH 52 652 609  HOH HOH B . 
T 5 HOH 53 653 551  HOH HOH B . 
T 5 HOH 54 654 72   HOH HOH B . 
T 5 HOH 55 655 624  HOH HOH B . 
T 5 HOH 56 656 630  HOH HOH B . 
T 5 HOH 57 657 502  HOH HOH B . 
T 5 HOH 58 658 659  HOH HOH B . 
T 5 HOH 59 659 581  HOH HOH B . 
T 5 HOH 60 660 559  HOH HOH B . 
T 5 HOH 61 661 637  HOH HOH B . 
T 5 HOH 62 662 606  HOH HOH B . 
T 5 HOH 63 663 638  HOH HOH B . 
T 5 HOH 64 664 634  HOH HOH B . 
T 5 HOH 65 665 656  HOH HOH B . 
T 5 HOH 66 666 640  HOH HOH B . 
T 5 HOH 67 667 459  HOH HOH B . 
T 5 HOH 68 668 621  HOH HOH B . 
T 5 HOH 69 669 507  HOH HOH B . 
T 5 HOH 70 670 669  HOH HOH B . 
T 5 HOH 71 671 662  HOH HOH B . 
T 5 HOH 72 672 586  HOH HOH B . 
T 5 HOH 73 673 676  HOH HOH B . 
T 5 HOH 74 674 672  HOH HOH B . 
U 5 HOH 1  601 437  HOH HOH C . 
U 5 HOH 2  602 414  HOH HOH C . 
U 5 HOH 3  603 420  HOH HOH C . 
U 5 HOH 4  604 69   HOH HOH C . 
U 5 HOH 5  605 438  HOH HOH C . 
U 5 HOH 6  606 423  HOH HOH C . 
U 5 HOH 7  607 430  HOH HOH C . 
U 5 HOH 8  608 407  HOH HOH C . 
U 5 HOH 9  609 439  HOH HOH C . 
U 5 HOH 10 610 468  HOH HOH C . 
U 5 HOH 11 611 431  HOH HOH C . 
U 5 HOH 12 612 448  HOH HOH C . 
U 5 HOH 13 613 445  HOH HOH C . 
U 5 HOH 14 614 17   HOH HOH C . 
U 5 HOH 15 615 472  HOH HOH C . 
U 5 HOH 16 616 432  HOH HOH C . 
U 5 HOH 17 617 417  HOH HOH C . 
U 5 HOH 18 618 455  HOH HOH C . 
U 5 HOH 19 619 436  HOH HOH C . 
U 5 HOH 20 620 6    HOH HOH C . 
U 5 HOH 21 621 464  HOH HOH C . 
U 5 HOH 22 622 451  HOH HOH C . 
U 5 HOH 23 623 415  HOH HOH C . 
U 5 HOH 24 624 477  HOH HOH C . 
U 5 HOH 25 625 558  HOH HOH C . 
U 5 HOH 26 626 426  HOH HOH C . 
U 5 HOH 27 627 40   HOH HOH C . 
U 5 HOH 28 628 450  HOH HOH C . 
U 5 HOH 29 629 446  HOH HOH C . 
U 5 HOH 30 630 412  HOH HOH C . 
U 5 HOH 31 631 442  HOH HOH C . 
U 5 HOH 32 632 45   HOH HOH C . 
U 5 HOH 33 633 37   HOH HOH C . 
U 5 HOH 34 634 447  HOH HOH C . 
U 5 HOH 35 635 509  HOH HOH C . 
U 5 HOH 36 636 471  HOH HOH C . 
U 5 HOH 37 637 461  HOH HOH C . 
U 5 HOH 38 638 473  HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ETB 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.151 
_cell.length_a_esd                 ? 
_cell.length_b                     133.667 
_cell.length_b_esd                 ? 
_cell.length_c                     147.94 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ETB 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ETB 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.81 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.26 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ETB 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.76 
_reflns.d_resolution_low                               147.94 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     38283 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.982 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.445 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.76 
_reflns_shell.d_res_low                                     2.88 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4851 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               12.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.489 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.1 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  2.173 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -1.216 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.378 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.839 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               46.127 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.930 
_refine.correlation_coeff_Fo_to_Fc_free          0.913 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ETB 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.760 
_refine.ls_d_res_low                             99.377 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     38242 
_refine.ls_number_reflns_R_free                  1861 
_refine.ls_number_reflns_R_work                  36381 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.147 
_refine.ls_percent_reflns_R_free                 4.866 
_refine.ls_R_factor_all                          0.213 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2280 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2122 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.225 
_refine.ls_wR_factor_R_work                      0.195 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  0.325 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9623 
_refine.pdbx_average_fsc_free                    0.9551 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.760 
_refine_hist.d_res_low                        99.377 
_refine_hist.number_atoms_solvent             244 
_refine_hist.number_atoms_total               9332 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8983 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         105 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  9330  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.649  1.852  12659 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.281  5.000  1113  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 26.513 5.000  44    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.059 10.000 1610  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.703 10.000 403   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.093  0.200  1426  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020  6985  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.232  0.200  4553  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.319  0.200  6321  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.161  0.200  403   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.326  0.200  67    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.311  0.200  7     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.497  4.499  4464  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.195  8.083  5573  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.746  4.722  4866  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.086  8.575  7086  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.287  49.789 14298 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.760  2.832  2806 . 121 2645 98.5745 . 0.430 . . 0.430 . . . . . 0.427 . 20 . 0.908 0.916 0.421 
'X-RAY DIFFRACTION' 2.832  2.909  2717 . 156 2524 98.6382 . 0.355 . . 0.353 . . . . . 0.348 . 20 . 0.922 0.903 0.375 
'X-RAY DIFFRACTION' 2.909  2.993  2673 . 153 2497 99.1395 . 0.313 . . 0.311 . . . . . 0.304 . 20 . 0.934 0.915 0.352 
'X-RAY DIFFRACTION' 2.993  3.086  2601 . 133 2441 98.9619 . 0.271 . . 0.271 . . . . . 0.260 . 20 . 0.950 0.951 0.266 
'X-RAY DIFFRACTION' 3.086  3.187  2512 . 125 2352 98.6067 . 0.259 . . 0.258 . . . . . 0.248 . 20 . 0.955 0.949 0.272 
'X-RAY DIFFRACTION' 3.187  3.298  2405 . 121 2267 99.2931 . 0.241 . . 0.241 . . . . . 0.231 . 20 . 0.963 0.962 0.251 
'X-RAY DIFFRACTION' 3.298  3.423  2370 . 125 2220 98.9451 . 0.223 . . 0.221 . . . . . 0.209 . 20 . 0.971 0.957 0.258 
'X-RAY DIFFRACTION' 3.423  3.562  2272 . 110 2145 99.2518 . 0.208 . . 0.208 . . . . . 0.197 . 20 . 0.975 0.972 0.211 
'X-RAY DIFFRACTION' 3.562  3.720  2188 . 88  2078 98.9945 . 0.197 . . 0.197 . . . . . 0.183 . 20 . 0.978 0.970 0.208 
'X-RAY DIFFRACTION' 3.720  3.902  2087 . 93  1984 99.5208 . 0.183 . . 0.184 . . . . . 0.174 . 20 . 0.980 0.978 0.173 
'X-RAY DIFFRACTION' 3.902  4.112  1996 . 94  1887 99.2485 . 0.161 . . 0.161 . . . . . 0.151 . 20 . 0.984 0.981 0.170 
'X-RAY DIFFRACTION' 4.112  4.361  1898 . 74  1811 99.3151 . 0.162 . . 0.162 . . . . . 0.154 . 20 . 0.984 0.984 0.164 
'X-RAY DIFFRACTION' 4.361  4.662  1758 . 81  1667 99.4312 . 0.154 . . 0.153 . . . . . 0.146 . 20 . 0.986 0.974 0.184 
'X-RAY DIFFRACTION' 4.662  5.035  1654 . 71  1574 99.4559 . 0.163 . . 0.163 . . . . . 0.156 . 20 . 0.984 0.982 0.163 
'X-RAY DIFFRACTION' 5.035  5.514  1546 . 81  1458 99.5472 . 0.180 . . 0.179 . . . . . 0.172 . 20 . 0.981 0.976 0.211 
'X-RAY DIFFRACTION' 5.514  6.162  1410 . 68  1336 99.5745 . 0.212 . . 0.212 . . . . . 0.202 . 20 . 0.976 0.977 0.229 
'X-RAY DIFFRACTION' 6.162  7.111  1243 . 55  1182 99.5173 . 0.219 . . 0.222 . . . . . 0.215 . 20 . 0.974 0.977 0.177 
'X-RAY DIFFRACTION' 7.111  8.698  1071 . 47  1021 99.7199 . 0.180 . . 0.179 . . . . . 0.179 . 20 . 0.981 0.979 0.194 
'X-RAY DIFFRACTION' 8.698  12.254 850  . 35  813  99.7647 . 0.159 . . 0.157 . . . . . 0.165 . 20 . 0.987 0.977 0.201 
'X-RAY DIFFRACTION' 12.254 99.377 514  . 30  479  99.0272 . 0.277 . . 0.276 . . . . . 0.323 . 20 . 0.951 0.938 0.293 
# 
_struct.entry_id                     9ETB 
_struct.title                        'CDK2-cyclin A in complex with FragLite 2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ETB 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
O N N 3 ? 
P N N 3 ? 
Q N N 4 ? 
R N N 5 ? 
S N N 5 ? 
T N N 5 ? 
U N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CCNA2_BOVIN P30274 ? 1 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
2 UNP CDK2_HUMAN  P24941 ? 2 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ETB D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
2 2 9ETB A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
3 1 9ETB B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
4 2 9ETB C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ETB GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 1  
1 9ETB HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 2  
1 9ETB HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 3  
1 9ETB HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 4  
1 9ETB HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 5  
1 9ETB HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 6  
1 9ETB HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 7  
2 9ETB GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  8  
2 9ETB PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  9  
2 9ETB GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  10 
2 9ETB SER A 4   ? UNP P24941 ? ? 'expression tag' 0   11 
3 9ETB GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 12 
3 9ETB HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 13 
3 9ETB HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 14 
3 9ETB HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 15 
3 9ETB HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 16 
3 9ETB HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 17 
3 9ETB HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 18 
4 9ETB GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  19 
4 9ETB PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  20 
4 9ETB GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  21 
4 9ETB SER C 4   ? UNP P24941 ? ? 'expression tag' 0   22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 4820  ? 
1 MORE         -10   ? 
1 'SSA (A^2)'  23090 ? 
2 'ABSA (A^2)' 6130  ? 
2 MORE         0     ? 
2 'SSA (A^2)'  24110 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E,N,O,P,Q,R,U       
2 1 B,C,F,G,H,I,J,K,L,M,S,T 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 1   ? VAL A 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P2  AA2 TYR A 8   ? CYS A 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P3  AA3 GLY A 28  ? LYS A 32  ? GLY D 198 LYS D 202 5 ? 5  
HELX_P HELX_P4  AA4 THR A 37  ? TYR A 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P5  AA5 GLN A 58  ? SER A 74  ? GLN D 228 SER D 244 1 ? 17 
HELX_P HELX_P6  AA6 LEU A 79  ? GLY A 81  ? LEU D 249 GLY D 251 5 ? 3  
HELX_P HELX_P7  AA7 LYS A 82  ? GLU A 99  ? LYS D 252 GLU D 269 1 ? 18 
HELX_P HELX_P8  AA8 GLU A 104 ? ILE A 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P9  AA9 THR A 117 ? ALA A 133 ? THR D 287 ALA D 303 1 ? 17 
HELX_P HELX_P10 AB1 THR A 140 ? PHE A 149 ? THR D 310 PHE D 319 1 ? 10 
HELX_P HELX_P11 AB2 LEU A 150 ? GLN A 152 ? LEU D 320 GLN D 322 5 ? 3  
HELX_P HELX_P12 AB3 ASN A 156 ? ASP A 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P13 AB4 ASP A 173 ? LEU A 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P14 AB5 LEU A 181 ? GLY A 199 ? LEU D 351 GLY D 369 1 ? 19 
HELX_P HELX_P15 AB6 GLU A 204 ? GLY A 211 ? GLU D 374 GLY D 381 1 ? 8  
HELX_P HELX_P16 AB7 LEU A 217 ? ARG A 230 ? LEU D 387 ARG D 400 1 ? 14 
HELX_P HELX_P17 AB8 ALA A 231 ? HIS A 234 ? ALA D 401 HIS D 404 5 ? 4  
HELX_P HELX_P18 AB9 GLN A 237 ? TYR A 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P19 AC1 LYS A 244 ? HIS A 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P20 AC2 SER B 4   ? GLU B 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P21 AC3 PRO B 49  ? LEU B 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P22 AC4 LEU B 91  ? SER B 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P23 AC5 PRO B 104 ? HIS B 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P24 AC6 LYS B 133 ? GLN B 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P25 AC7 THR B 169 ? ARG B 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P26 AC8 ALA B 174 ? LEU B 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P27 AC9 THR B 186 ? ARG B 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P28 AD1 SER B 211 ? GLY B 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P29 AD2 GLY B 233 ? MET B 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P30 AD3 ASP B 260 ? LEU B 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P31 AD4 SER B 280 ? LEU B 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P32 AD5 ALA B 286 ? GLN B 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P33 AD6 GLY C 1   ? VAL C 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P34 AD7 TYR C 8   ? CYS C 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P35 AD8 THR C 37  ? LYS C 56  ? THR B 207 LYS B 226 1 ? 20 
HELX_P HELX_P36 AD9 GLN C 58  ? SER C 74  ? GLN B 228 SER B 244 1 ? 17 
HELX_P HELX_P37 AE1 LEU C 79  ? GLY C 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P38 AE2 LYS C 82  ? GLU C 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P39 AE3 GLU C 104 ? ILE C 111 ? GLU B 274 ILE B 281 1 ? 8  
HELX_P HELX_P40 AE4 THR C 117 ? LEU C 132 ? THR B 287 LEU B 302 1 ? 16 
HELX_P HELX_P41 AE5 THR C 140 ? LEU C 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P42 AE6 ASN C 156 ? ASP C 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P43 AE7 ASP C 173 ? LEU C 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P44 AE8 LEU C 181 ? GLY C 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P45 AE9 PRO C 203 ? GLY C 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P46 AF1 THR C 213 ? ALA C 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P47 AF2 PRO C 232 ? HIS C 234 ? PRO B 402 HIS B 404 5 ? 3  
HELX_P HELX_P48 AF3 GLN C 237 ? TYR C 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P49 AF4 LYS C 244 ? HIS C 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P50 AF5 GLY C 250 ? LEU C 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P51 AF6 PRO D 49  ? LEU D 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P52 AF7 LEU D 91  ? SER D 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P53 AF8 PRO D 104 ? HIS D 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P54 AF9 LYS D 133 ? GLN D 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P55 AG1 THR D 169 ? ARG D 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P56 AG2 ALA D 174 ? LEU D 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P57 AG3 THR D 186 ? ARG D 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P58 AG4 SER D 211 ? GLY D 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P59 AG5 ASP D 260 ? LEU D 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P60 AG6 SER D 280 ? HIS D 287 ? SER C 276 HIS C 283 1 ? 8  
HELX_P HELX_P61 AG7 PRO D 288 ? VAL D 293 ? PRO C 284 VAL C 289 5 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? B TYR 163 C ? ? ? 1_555 B TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.339 ? ? 
covale2 covale both ? B TPO 164 C ? ? ? 1_555 B HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.337 ? ? 
covale3 covale both ? D TYR 163 C ? ? ? 1_555 D TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.334 ? ? 
covale4 covale both ? D TPO 164 C ? ? ? 1_555 D HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.338 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO B 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO D 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 153 A . ? GLN 323 D PRO 154 A ? PRO 324 D 1 -13.37 
2 ASP 175 A . ? ASP 345 D PRO 176 A ? PRO 346 D 1 9.56   
3 VAL 158 B . ? VAL 154 A PRO 159 B ? PRO 155 A 1 -7.24  
4 GLN 153 C . ? GLN 323 B PRO 154 C ? PRO 324 B 1 -6.86  
5 ASP 175 C . ? ASP 345 B PRO 176 C ? PRO 346 B 1 10.54  
6 VAL 158 D . ? VAL 154 C PRO 159 D ? PRO 155 C 1 -5.11  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 8   ? GLU B 16  ? PHE A 4   GLU A 12  
AA1 2 VAL B 21  ? ASN B 27  ? VAL A 17  ASN A 23  
AA1 3 VAL B 33  ? ARG B 40  ? VAL A 29  ARG A 36  
AA1 4 LYS B 79  ? GLU B 85  ? LYS A 75  GLU A 81  
AA1 5 LEU B 70  ? HIS B 75  ? LEU A 66  HIS A 71  
AA2 1 GLN B 89  ? ASP B 90  ? GLN A 85  ASP A 86  
AA2 2 LEU B 137 ? ILE B 139 ? LEU A 133 ILE A 135 
AA2 3 ILE B 145 ? LEU B 147 ? ILE A 141 LEU A 143 
AA3 1 VAL B 127 ? LEU B 128 ? VAL A 123 LEU A 124 
AA3 2 ARG B 154 ? ALA B 155 ? ARG A 150 ALA A 151 
AA4 1 PHE D 8   ? GLU D 16  ? PHE C 4   GLU C 12  
AA4 2 VAL D 21  ? ASN D 27  ? VAL C 17  ASN C 23  
AA4 3 VAL D 33  ? ARG D 40  ? VAL C 29  ARG C 36  
AA4 4 LYS D 79  ? GLU D 85  ? LYS C 75  GLU C 81  
AA4 5 LEU D 70  ? HIS D 75  ? LEU C 66  HIS C 71  
AA5 1 GLN D 89  ? ASP D 90  ? GLN C 85  ASP C 86  
AA5 2 LEU D 137 ? ILE D 139 ? LEU C 133 ILE C 135 
AA5 3 ILE D 145 ? LEU D 147 ? ILE C 141 LEU C 143 
AA6 1 VAL D 127 ? LEU D 128 ? VAL C 123 LEU C 124 
AA6 2 ARG D 154 ? ALA D 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY B 15  ? N GLY A 11  O VAL B 22  ? O VAL A 18  
AA1 2 3 N TYR B 23  ? N TYR A 19  O LEU B 36  ? O LEU A 32  
AA1 3 4 N ILE B 39  ? N ILE A 35  O LEU B 80  ? O LEU A 76  
AA1 4 5 O VAL B 83  ? O VAL A 79  N LEU B 71  ? N LEU A 67  
AA2 1 2 N GLN B 89  ? N GLN A 85  O ILE B 139 ? O ILE A 135 
AA2 2 3 N LEU B 138 ? N LEU A 134 O LYS B 146 ? O LYS A 142 
AA3 1 2 N LEU B 128 ? N LEU A 124 O ARG B 154 ? O ARG A 150 
AA4 1 2 N ILE D 14  ? N ILE C 10  O VAL D 22  ? O VAL C 18  
AA4 2 3 N ALA D 25  ? N ALA C 21  O VAL D 34  ? O VAL C 30  
AA4 3 4 N LYS D 37  ? N LYS C 33  O LEU D 82  ? O LEU C 78  
AA4 4 5 O VAL D 83  ? O VAL C 79  N LEU D 71  ? N LEU C 67  
AA5 1 2 N GLN D 89  ? N GLN C 85  O ILE D 139 ? O ILE C 135 
AA5 2 3 N LEU D 138 ? N LEU C 134 O LYS D 146 ? O LYS C 142 
AA6 1 2 N LEU D 128 ? N LEU C 124 O ARG D 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ETB 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N D PRO 346 ? ? CA D PRO 346 ? ? CB D PRO 346 ? ? 89.24 102.60 -13.36 1.10 N 
2 1 N B PRO 346 ? ? CA B PRO 346 ? ? CB B PRO 346 ? ? 89.96 102.60 -12.64 1.10 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL D 175 ? ? 31.55   70.70   
2  1 SER D 245 ? ? -140.62 -9.32   
3  1 TRP D 372 ? ? -38.25  114.41  
4  1 PRO D 402 ? ? -59.37  -9.60   
5  1 GLU A 73  ? ? 55.70   84.07   
6  1 SER A 94  ? ? -93.87  35.42   
7  1 ASP A 127 ? ? -154.92 45.17   
8  1 LYS A 129 ? ? 173.22  153.76  
9  1 ASP A 145 ? ? 52.18   79.05   
10 1 PHE A 146 ? ? -90.46  32.64   
11 1 VAL A 164 ? ? 77.56   126.12  
12 1 VAL B 175 ? ? 38.45   64.21   
13 1 TYR B 178 ? ? -140.77 -5.16   
14 1 ASP B 283 ? ? 44.83   22.60   
15 1 TRP B 372 ? ? -35.32  115.83  
16 1 SER B 422 ? ? -68.91  1.17    
17 1 THR C 41  ? ? -131.52 -86.38  
18 1 ASP C 127 ? ? -160.33 51.73   
19 1 ASP C 145 ? ? 51.51   80.46   
20 1 PHE C 146 ? ? -98.47  34.67   
21 1 ARG C 150 ? ? -172.27 128.35  
22 1 VAL C 164 ? ? 65.12   133.84  
23 1 SER C 181 ? ? -150.60 -157.32 
24 1 ASP C 223 ? ? -116.44 -74.86  
25 1 MET C 233 ? ? -47.57  109.24  
26 1 PHE C 240 ? ? -145.30 43.25   
27 1 THR C 290 ? ? -127.27 -166.49 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG D 250 ? ? 0.260 'SIDE CHAIN' 
2  1 ARG A 36  ? ? 0.228 'SIDE CHAIN' 
3  1 ARG A 122 ? ? 0.284 'SIDE CHAIN' 
4  1 ARG A 150 ? ? 0.175 'SIDE CHAIN' 
5  1 ARG A 217 ? ? 0.281 'SIDE CHAIN' 
6  1 ARG A 297 ? ? 0.226 'SIDE CHAIN' 
7  1 ARG B 211 ? ? 0.210 'SIDE CHAIN' 
8  1 ARG C 122 ? ? 0.242 'SIDE CHAIN' 
9  1 ARG C 214 ? ? 0.159 'SIDE CHAIN' 
10 1 ARG C 217 ? ? 0.225 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 B TPO 164 A TPO 160 ? THR 'modified residue' 
2 D TPO 164 C TPO 160 ? THR 'modified residue' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 D HIS 433 ? A HIS 263 
2  1 Y 1 D HIS 434 ? A HIS 264 
3  1 Y 1 D HIS 435 ? A HIS 265 
4  1 Y 1 D HIS 436 ? A HIS 266 
5  1 Y 1 D HIS 437 ? A HIS 267 
6  1 Y 1 D HIS 438 ? A HIS 268 
7  1 Y 1 A GLY -3  ? B GLY 1   
8  1 Y 1 C GLY -3  ? D GLY 1   
9  1 Y 1 C PRO -2  ? D PRO 2   
10 1 Y 1 C GLY -1  ? D GLY 3   
11 1 Y 1 C LYS 242 ? D LYS 246 
12 1 Y 1 C TRP 243 ? D TRP 247 
13 1 Y 1 C ALA 244 ? D ALA 248 
14 1 Y 1 C ARG 245 ? D ARG 249 
15 1 Y 1 C GLN 246 ? D GLN 250 
16 1 Y 1 C ASP 247 ? D ASP 251 
17 1 Y 1 C PHE 248 ? D PHE 252 
18 1 Y 1 C SER 249 ? D SER 253 
19 1 Y 1 C LYS 250 ? D LYS 254 
20 1 Y 1 C VAL 251 ? D VAL 255 
21 1 Y 1 C VAL 252 ? D VAL 256 
22 1 Y 1 C PRO 253 ? D PRO 257 
23 1 Y 1 C ARG 297 ? D ARG 301 
24 1 Y 1 C LEU 298 ? D LEU 302 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EPE N1   N N N 88  
EPE C2   C N N 89  
EPE C3   C N N 90  
EPE N4   N N N 91  
EPE C5   C N N 92  
EPE C6   C N N 93  
EPE C7   C N N 94  
EPE C8   C N N 95  
EPE O8   O N N 96  
EPE C9   C N N 97  
EPE C10  C N N 98  
EPE S    S N N 99  
EPE O1S  O N N 100 
EPE O2S  O N N 101 
EPE O3S  O N N 102 
EPE H21  H N N 103 
EPE H22  H N N 104 
EPE H31  H N N 105 
EPE H32  H N N 106 
EPE H51  H N N 107 
EPE H52  H N N 108 
EPE H61  H N N 109 
EPE H62  H N N 110 
EPE H71  H N N 111 
EPE H72  H N N 112 
EPE H81  H N N 113 
EPE H82  H N N 114 
EPE HO8  H N N 115 
EPE H91  H N N 116 
EPE H92  H N N 117 
EPE H101 H N N 118 
EPE H102 H N N 119 
EPE HOS3 H N N 120 
GLN N    N N N 121 
GLN CA   C N S 122 
GLN C    C N N 123 
GLN O    O N N 124 
GLN CB   C N N 125 
GLN CG   C N N 126 
GLN CD   C N N 127 
GLN OE1  O N N 128 
GLN NE2  N N N 129 
GLN OXT  O N N 130 
GLN H    H N N 131 
GLN H2   H N N 132 
GLN HA   H N N 133 
GLN HB2  H N N 134 
GLN HB3  H N N 135 
GLN HG2  H N N 136 
GLN HG3  H N N 137 
GLN HE21 H N N 138 
GLN HE22 H N N 139 
GLN HXT  H N N 140 
GLU N    N N N 141 
GLU CA   C N S 142 
GLU C    C N N 143 
GLU O    O N N 144 
GLU CB   C N N 145 
GLU CG   C N N 146 
GLU CD   C N N 147 
GLU OE1  O N N 148 
GLU OE2  O N N 149 
GLU OXT  O N N 150 
GLU H    H N N 151 
GLU H2   H N N 152 
GLU HA   H N N 153 
GLU HB2  H N N 154 
GLU HB3  H N N 155 
GLU HG2  H N N 156 
GLU HG3  H N N 157 
GLU HE2  H N N 158 
GLU HXT  H N N 159 
GLY N    N N N 160 
GLY CA   C N N 161 
GLY C    C N N 162 
GLY O    O N N 163 
GLY OXT  O N N 164 
GLY H    H N N 165 
GLY H2   H N N 166 
GLY HA2  H N N 167 
GLY HA3  H N N 168 
GLY HXT  H N N 169 
HIS N    N N N 170 
HIS CA   C N S 171 
HIS C    C N N 172 
HIS O    O N N 173 
HIS CB   C N N 174 
HIS CG   C Y N 175 
HIS ND1  N Y N 176 
HIS CD2  C Y N 177 
HIS CE1  C Y N 178 
HIS NE2  N Y N 179 
HIS OXT  O N N 180 
HIS H    H N N 181 
HIS H2   H N N 182 
HIS HA   H N N 183 
HIS HB2  H N N 184 
HIS HB3  H N N 185 
HIS HD1  H N N 186 
HIS HD2  H N N 187 
HIS HE1  H N N 188 
HIS HE2  H N N 189 
HIS HXT  H N N 190 
HOH O    O N N 191 
HOH H1   H N N 192 
HOH H2   H N N 193 
ILE N    N N N 194 
ILE CA   C N S 195 
ILE C    C N N 196 
ILE O    O N N 197 
ILE CB   C N S 198 
ILE CG1  C N N 199 
ILE CG2  C N N 200 
ILE CD1  C N N 201 
ILE OXT  O N N 202 
ILE H    H N N 203 
ILE H2   H N N 204 
ILE HA   H N N 205 
ILE HB   H N N 206 
ILE HG12 H N N 207 
ILE HG13 H N N 208 
ILE HG21 H N N 209 
ILE HG22 H N N 210 
ILE HG23 H N N 211 
ILE HD11 H N N 212 
ILE HD12 H N N 213 
ILE HD13 H N N 214 
ILE HXT  H N N 215 
LEU N    N N N 216 
LEU CA   C N S 217 
LEU C    C N N 218 
LEU O    O N N 219 
LEU CB   C N N 220 
LEU CG   C N N 221 
LEU CD1  C N N 222 
LEU CD2  C N N 223 
LEU OXT  O N N 224 
LEU H    H N N 225 
LEU H2   H N N 226 
LEU HA   H N N 227 
LEU HB2  H N N 228 
LEU HB3  H N N 229 
LEU HG   H N N 230 
LEU HD11 H N N 231 
LEU HD12 H N N 232 
LEU HD13 H N N 233 
LEU HD21 H N N 234 
LEU HD22 H N N 235 
LEU HD23 H N N 236 
LEU HXT  H N N 237 
LYS N    N N N 238 
LYS CA   C N S 239 
LYS C    C N N 240 
LYS O    O N N 241 
LYS CB   C N N 242 
LYS CG   C N N 243 
LYS CD   C N N 244 
LYS CE   C N N 245 
LYS NZ   N N N 246 
LYS OXT  O N N 247 
LYS H    H N N 248 
LYS H2   H N N 249 
LYS HA   H N N 250 
LYS HB2  H N N 251 
LYS HB3  H N N 252 
LYS HG2  H N N 253 
LYS HG3  H N N 254 
LYS HD2  H N N 255 
LYS HD3  H N N 256 
LYS HE2  H N N 257 
LYS HE3  H N N 258 
LYS HZ1  H N N 259 
LYS HZ2  H N N 260 
LYS HZ3  H N N 261 
LYS HXT  H N N 262 
MET N    N N N 263 
MET CA   C N S 264 
MET C    C N N 265 
MET O    O N N 266 
MET CB   C N N 267 
MET CG   C N N 268 
MET SD   S N N 269 
MET CE   C N N 270 
MET OXT  O N N 271 
MET H    H N N 272 
MET H2   H N N 273 
MET HA   H N N 274 
MET HB2  H N N 275 
MET HB3  H N N 276 
MET HG2  H N N 277 
MET HG3  H N N 278 
MET HE1  H N N 279 
MET HE2  H N N 280 
MET HE3  H N N 281 
MET HXT  H N N 282 
PHE N    N N N 283 
PHE CA   C N S 284 
PHE C    C N N 285 
PHE O    O N N 286 
PHE CB   C N N 287 
PHE CG   C Y N 288 
PHE CD1  C Y N 289 
PHE CD2  C Y N 290 
PHE CE1  C Y N 291 
PHE CE2  C Y N 292 
PHE CZ   C Y N 293 
PHE OXT  O N N 294 
PHE H    H N N 295 
PHE H2   H N N 296 
PHE HA   H N N 297 
PHE HB2  H N N 298 
PHE HB3  H N N 299 
PHE HD1  H N N 300 
PHE HD2  H N N 301 
PHE HE1  H N N 302 
PHE HE2  H N N 303 
PHE HZ   H N N 304 
PHE HXT  H N N 305 
PRO N    N N N 306 
PRO CA   C N S 307 
PRO C    C N N 308 
PRO O    O N N 309 
PRO CB   C N N 310 
PRO CG   C N N 311 
PRO CD   C N N 312 
PRO OXT  O N N 313 
PRO H    H N N 314 
PRO HA   H N N 315 
PRO HB2  H N N 316 
PRO HB3  H N N 317 
PRO HG2  H N N 318 
PRO HG3  H N N 319 
PRO HD2  H N N 320 
PRO HD3  H N N 321 
PRO HXT  H N N 322 
PYZ N1   N Y N 323 
PYZ N2   N Y N 324 
PYZ C3   C Y N 325 
PYZ C4   C Y N 326 
PYZ I4   I N N 327 
PYZ C5   C Y N 328 
PYZ HN1  H N N 329 
PYZ H3   H N N 330 
PYZ H5   H N N 331 
SER N    N N N 332 
SER CA   C N S 333 
SER C    C N N 334 
SER O    O N N 335 
SER CB   C N N 336 
SER OG   O N N 337 
SER OXT  O N N 338 
SER H    H N N 339 
SER H2   H N N 340 
SER HA   H N N 341 
SER HB2  H N N 342 
SER HB3  H N N 343 
SER HG   H N N 344 
SER HXT  H N N 345 
THR N    N N N 346 
THR CA   C N S 347 
THR C    C N N 348 
THR O    O N N 349 
THR CB   C N R 350 
THR OG1  O N N 351 
THR CG2  C N N 352 
THR OXT  O N N 353 
THR H    H N N 354 
THR H2   H N N 355 
THR HA   H N N 356 
THR HB   H N N 357 
THR HG1  H N N 358 
THR HG21 H N N 359 
THR HG22 H N N 360 
THR HG23 H N N 361 
THR HXT  H N N 362 
TPO N    N N N 363 
TPO CA   C N S 364 
TPO CB   C N R 365 
TPO CG2  C N N 366 
TPO OG1  O N N 367 
TPO P    P N N 368 
TPO O1P  O N N 369 
TPO O2P  O N N 370 
TPO O3P  O N N 371 
TPO C    C N N 372 
TPO O    O N N 373 
TPO OXT  O N N 374 
TPO H    H N N 375 
TPO H2   H N N 376 
TPO HA   H N N 377 
TPO HB   H N N 378 
TPO HG21 H N N 379 
TPO HG22 H N N 380 
TPO HG23 H N N 381 
TPO HOP2 H N N 382 
TPO HOP3 H N N 383 
TPO HXT  H N N 384 
TRP N    N N N 385 
TRP CA   C N S 386 
TRP C    C N N 387 
TRP O    O N N 388 
TRP CB   C N N 389 
TRP CG   C Y N 390 
TRP CD1  C Y N 391 
TRP CD2  C Y N 392 
TRP NE1  N Y N 393 
TRP CE2  C Y N 394 
TRP CE3  C Y N 395 
TRP CZ2  C Y N 396 
TRP CZ3  C Y N 397 
TRP CH2  C Y N 398 
TRP OXT  O N N 399 
TRP H    H N N 400 
TRP H2   H N N 401 
TRP HA   H N N 402 
TRP HB2  H N N 403 
TRP HB3  H N N 404 
TRP HD1  H N N 405 
TRP HE1  H N N 406 
TRP HE3  H N N 407 
TRP HZ2  H N N 408 
TRP HZ3  H N N 409 
TRP HH2  H N N 410 
TRP HXT  H N N 411 
TYR N    N N N 412 
TYR CA   C N S 413 
TYR C    C N N 414 
TYR O    O N N 415 
TYR CB   C N N 416 
TYR CG   C Y N 417 
TYR CD1  C Y N 418 
TYR CD2  C Y N 419 
TYR CE1  C Y N 420 
TYR CE2  C Y N 421 
TYR CZ   C Y N 422 
TYR OH   O N N 423 
TYR OXT  O N N 424 
TYR H    H N N 425 
TYR H2   H N N 426 
TYR HA   H N N 427 
TYR HB2  H N N 428 
TYR HB3  H N N 429 
TYR HD1  H N N 430 
TYR HD2  H N N 431 
TYR HE1  H N N 432 
TYR HE2  H N N 433 
TYR HH   H N N 434 
TYR HXT  H N N 435 
VAL N    N N N 436 
VAL CA   C N S 437 
VAL C    C N N 438 
VAL O    O N N 439 
VAL CB   C N N 440 
VAL CG1  C N N 441 
VAL CG2  C N N 442 
VAL OXT  O N N 443 
VAL H    H N N 444 
VAL H2   H N N 445 
VAL HA   H N N 446 
VAL HB   H N N 447 
VAL HG11 H N N 448 
VAL HG12 H N N 449 
VAL HG13 H N N 450 
VAL HG21 H N N 451 
VAL HG22 H N N 452 
VAL HG23 H N N 453 
VAL HXT  H N N 454 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EPE N1  C2   sing N N 83  
EPE N1  C6   sing N N 84  
EPE N1  C9   sing N N 85  
EPE C2  C3   sing N N 86  
EPE C2  H21  sing N N 87  
EPE C2  H22  sing N N 88  
EPE C3  N4   sing N N 89  
EPE C3  H31  sing N N 90  
EPE C3  H32  sing N N 91  
EPE N4  C5   sing N N 92  
EPE N4  C7   sing N N 93  
EPE C5  C6   sing N N 94  
EPE C5  H51  sing N N 95  
EPE C5  H52  sing N N 96  
EPE C6  H61  sing N N 97  
EPE C6  H62  sing N N 98  
EPE C7  C8   sing N N 99  
EPE C7  H71  sing N N 100 
EPE C7  H72  sing N N 101 
EPE C8  O8   sing N N 102 
EPE C8  H81  sing N N 103 
EPE C8  H82  sing N N 104 
EPE O8  HO8  sing N N 105 
EPE C9  C10  sing N N 106 
EPE C9  H91  sing N N 107 
EPE C9  H92  sing N N 108 
EPE C10 S    sing N N 109 
EPE C10 H101 sing N N 110 
EPE C10 H102 sing N N 111 
EPE S   O1S  doub N N 112 
EPE S   O2S  doub N N 113 
EPE S   O3S  sing N N 114 
EPE O3S HOS3 sing N N 115 
GLN N   CA   sing N N 116 
GLN N   H    sing N N 117 
GLN N   H2   sing N N 118 
GLN CA  C    sing N N 119 
GLN CA  CB   sing N N 120 
GLN CA  HA   sing N N 121 
GLN C   O    doub N N 122 
GLN C   OXT  sing N N 123 
GLN CB  CG   sing N N 124 
GLN CB  HB2  sing N N 125 
GLN CB  HB3  sing N N 126 
GLN CG  CD   sing N N 127 
GLN CG  HG2  sing N N 128 
GLN CG  HG3  sing N N 129 
GLN CD  OE1  doub N N 130 
GLN CD  NE2  sing N N 131 
GLN NE2 HE21 sing N N 132 
GLN NE2 HE22 sing N N 133 
GLN OXT HXT  sing N N 134 
GLU N   CA   sing N N 135 
GLU N   H    sing N N 136 
GLU N   H2   sing N N 137 
GLU CA  C    sing N N 138 
GLU CA  CB   sing N N 139 
GLU CA  HA   sing N N 140 
GLU C   O    doub N N 141 
GLU C   OXT  sing N N 142 
GLU CB  CG   sing N N 143 
GLU CB  HB2  sing N N 144 
GLU CB  HB3  sing N N 145 
GLU CG  CD   sing N N 146 
GLU CG  HG2  sing N N 147 
GLU CG  HG3  sing N N 148 
GLU CD  OE1  doub N N 149 
GLU CD  OE2  sing N N 150 
GLU OE2 HE2  sing N N 151 
GLU OXT HXT  sing N N 152 
GLY N   CA   sing N N 153 
GLY N   H    sing N N 154 
GLY N   H2   sing N N 155 
GLY CA  C    sing N N 156 
GLY CA  HA2  sing N N 157 
GLY CA  HA3  sing N N 158 
GLY C   O    doub N N 159 
GLY C   OXT  sing N N 160 
GLY OXT HXT  sing N N 161 
HIS N   CA   sing N N 162 
HIS N   H    sing N N 163 
HIS N   H2   sing N N 164 
HIS CA  C    sing N N 165 
HIS CA  CB   sing N N 166 
HIS CA  HA   sing N N 167 
HIS C   O    doub N N 168 
HIS C   OXT  sing N N 169 
HIS CB  CG   sing N N 170 
HIS CB  HB2  sing N N 171 
HIS CB  HB3  sing N N 172 
HIS CG  ND1  sing Y N 173 
HIS CG  CD2  doub Y N 174 
HIS ND1 CE1  doub Y N 175 
HIS ND1 HD1  sing N N 176 
HIS CD2 NE2  sing Y N 177 
HIS CD2 HD2  sing N N 178 
HIS CE1 NE2  sing Y N 179 
HIS CE1 HE1  sing N N 180 
HIS NE2 HE2  sing N N 181 
HIS OXT HXT  sing N N 182 
HOH O   H1   sing N N 183 
HOH O   H2   sing N N 184 
ILE N   CA   sing N N 185 
ILE N   H    sing N N 186 
ILE N   H2   sing N N 187 
ILE CA  C    sing N N 188 
ILE CA  CB   sing N N 189 
ILE CA  HA   sing N N 190 
ILE C   O    doub N N 191 
ILE C   OXT  sing N N 192 
ILE CB  CG1  sing N N 193 
ILE CB  CG2  sing N N 194 
ILE CB  HB   sing N N 195 
ILE CG1 CD1  sing N N 196 
ILE CG1 HG12 sing N N 197 
ILE CG1 HG13 sing N N 198 
ILE CG2 HG21 sing N N 199 
ILE CG2 HG22 sing N N 200 
ILE CG2 HG23 sing N N 201 
ILE CD1 HD11 sing N N 202 
ILE CD1 HD12 sing N N 203 
ILE CD1 HD13 sing N N 204 
ILE OXT HXT  sing N N 205 
LEU N   CA   sing N N 206 
LEU N   H    sing N N 207 
LEU N   H2   sing N N 208 
LEU CA  C    sing N N 209 
LEU CA  CB   sing N N 210 
LEU CA  HA   sing N N 211 
LEU C   O    doub N N 212 
LEU C   OXT  sing N N 213 
LEU CB  CG   sing N N 214 
LEU CB  HB2  sing N N 215 
LEU CB  HB3  sing N N 216 
LEU CG  CD1  sing N N 217 
LEU CG  CD2  sing N N 218 
LEU CG  HG   sing N N 219 
LEU CD1 HD11 sing N N 220 
LEU CD1 HD12 sing N N 221 
LEU CD1 HD13 sing N N 222 
LEU CD2 HD21 sing N N 223 
LEU CD2 HD22 sing N N 224 
LEU CD2 HD23 sing N N 225 
LEU OXT HXT  sing N N 226 
LYS N   CA   sing N N 227 
LYS N   H    sing N N 228 
LYS N   H2   sing N N 229 
LYS CA  C    sing N N 230 
LYS CA  CB   sing N N 231 
LYS CA  HA   sing N N 232 
LYS C   O    doub N N 233 
LYS C   OXT  sing N N 234 
LYS CB  CG   sing N N 235 
LYS CB  HB2  sing N N 236 
LYS CB  HB3  sing N N 237 
LYS CG  CD   sing N N 238 
LYS CG  HG2  sing N N 239 
LYS CG  HG3  sing N N 240 
LYS CD  CE   sing N N 241 
LYS CD  HD2  sing N N 242 
LYS CD  HD3  sing N N 243 
LYS CE  NZ   sing N N 244 
LYS CE  HE2  sing N N 245 
LYS CE  HE3  sing N N 246 
LYS NZ  HZ1  sing N N 247 
LYS NZ  HZ2  sing N N 248 
LYS NZ  HZ3  sing N N 249 
LYS OXT HXT  sing N N 250 
MET N   CA   sing N N 251 
MET N   H    sing N N 252 
MET N   H2   sing N N 253 
MET CA  C    sing N N 254 
MET CA  CB   sing N N 255 
MET CA  HA   sing N N 256 
MET C   O    doub N N 257 
MET C   OXT  sing N N 258 
MET CB  CG   sing N N 259 
MET CB  HB2  sing N N 260 
MET CB  HB3  sing N N 261 
MET CG  SD   sing N N 262 
MET CG  HG2  sing N N 263 
MET CG  HG3  sing N N 264 
MET SD  CE   sing N N 265 
MET CE  HE1  sing N N 266 
MET CE  HE2  sing N N 267 
MET CE  HE3  sing N N 268 
MET OXT HXT  sing N N 269 
PHE N   CA   sing N N 270 
PHE N   H    sing N N 271 
PHE N   H2   sing N N 272 
PHE CA  C    sing N N 273 
PHE CA  CB   sing N N 274 
PHE CA  HA   sing N N 275 
PHE C   O    doub N N 276 
PHE C   OXT  sing N N 277 
PHE CB  CG   sing N N 278 
PHE CB  HB2  sing N N 279 
PHE CB  HB3  sing N N 280 
PHE CG  CD1  doub Y N 281 
PHE CG  CD2  sing Y N 282 
PHE CD1 CE1  sing Y N 283 
PHE CD1 HD1  sing N N 284 
PHE CD2 CE2  doub Y N 285 
PHE CD2 HD2  sing N N 286 
PHE CE1 CZ   doub Y N 287 
PHE CE1 HE1  sing N N 288 
PHE CE2 CZ   sing Y N 289 
PHE CE2 HE2  sing N N 290 
PHE CZ  HZ   sing N N 291 
PHE OXT HXT  sing N N 292 
PRO N   CA   sing N N 293 
PRO N   CD   sing N N 294 
PRO N   H    sing N N 295 
PRO CA  C    sing N N 296 
PRO CA  CB   sing N N 297 
PRO CA  HA   sing N N 298 
PRO C   O    doub N N 299 
PRO C   OXT  sing N N 300 
PRO CB  CG   sing N N 301 
PRO CB  HB2  sing N N 302 
PRO CB  HB3  sing N N 303 
PRO CG  CD   sing N N 304 
PRO CG  HG2  sing N N 305 
PRO CG  HG3  sing N N 306 
PRO CD  HD2  sing N N 307 
PRO CD  HD3  sing N N 308 
PRO OXT HXT  sing N N 309 
PYZ N1  N2   sing Y N 310 
PYZ N1  C5   sing Y N 311 
PYZ N1  HN1  sing N N 312 
PYZ N2  C3   doub Y N 313 
PYZ C3  C4   sing Y N 314 
PYZ C3  H3   sing N N 315 
PYZ C4  I4   sing N N 316 
PYZ C4  C5   doub Y N 317 
PYZ C5  H5   sing N N 318 
SER N   CA   sing N N 319 
SER N   H    sing N N 320 
SER N   H2   sing N N 321 
SER CA  C    sing N N 322 
SER CA  CB   sing N N 323 
SER CA  HA   sing N N 324 
SER C   O    doub N N 325 
SER C   OXT  sing N N 326 
SER CB  OG   sing N N 327 
SER CB  HB2  sing N N 328 
SER CB  HB3  sing N N 329 
SER OG  HG   sing N N 330 
SER OXT HXT  sing N N 331 
THR N   CA   sing N N 332 
THR N   H    sing N N 333 
THR N   H2   sing N N 334 
THR CA  C    sing N N 335 
THR CA  CB   sing N N 336 
THR CA  HA   sing N N 337 
THR C   O    doub N N 338 
THR C   OXT  sing N N 339 
THR CB  OG1  sing N N 340 
THR CB  CG2  sing N N 341 
THR CB  HB   sing N N 342 
THR OG1 HG1  sing N N 343 
THR CG2 HG21 sing N N 344 
THR CG2 HG22 sing N N 345 
THR CG2 HG23 sing N N 346 
THR OXT HXT  sing N N 347 
TPO N   CA   sing N N 348 
TPO N   H    sing N N 349 
TPO N   H2   sing N N 350 
TPO CA  CB   sing N N 351 
TPO CA  C    sing N N 352 
TPO CA  HA   sing N N 353 
TPO CB  CG2  sing N N 354 
TPO CB  OG1  sing N N 355 
TPO CB  HB   sing N N 356 
TPO CG2 HG21 sing N N 357 
TPO CG2 HG22 sing N N 358 
TPO CG2 HG23 sing N N 359 
TPO OG1 P    sing N N 360 
TPO P   O1P  doub N N 361 
TPO P   O2P  sing N N 362 
TPO P   O3P  sing N N 363 
TPO O2P HOP2 sing N N 364 
TPO O3P HOP3 sing N N 365 
TPO C   O    doub N N 366 
TPO C   OXT  sing N N 367 
TPO OXT HXT  sing N N 368 
TRP N   CA   sing N N 369 
TRP N   H    sing N N 370 
TRP N   H2   sing N N 371 
TRP CA  C    sing N N 372 
TRP CA  CB   sing N N 373 
TRP CA  HA   sing N N 374 
TRP C   O    doub N N 375 
TRP C   OXT  sing N N 376 
TRP CB  CG   sing N N 377 
TRP CB  HB2  sing N N 378 
TRP CB  HB3  sing N N 379 
TRP CG  CD1  doub Y N 380 
TRP CG  CD2  sing Y N 381 
TRP CD1 NE1  sing Y N 382 
TRP CD1 HD1  sing N N 383 
TRP CD2 CE2  doub Y N 384 
TRP CD2 CE3  sing Y N 385 
TRP NE1 CE2  sing Y N 386 
TRP NE1 HE1  sing N N 387 
TRP CE2 CZ2  sing Y N 388 
TRP CE3 CZ3  doub Y N 389 
TRP CE3 HE3  sing N N 390 
TRP CZ2 CH2  doub Y N 391 
TRP CZ2 HZ2  sing N N 392 
TRP CZ3 CH2  sing Y N 393 
TRP CZ3 HZ3  sing N N 394 
TRP CH2 HH2  sing N N 395 
TRP OXT HXT  sing N N 396 
TYR N   CA   sing N N 397 
TYR N   H    sing N N 398 
TYR N   H2   sing N N 399 
TYR CA  C    sing N N 400 
TYR CA  CB   sing N N 401 
TYR CA  HA   sing N N 402 
TYR C   O    doub N N 403 
TYR C   OXT  sing N N 404 
TYR CB  CG   sing N N 405 
TYR CB  HB2  sing N N 406 
TYR CB  HB3  sing N N 407 
TYR CG  CD1  doub Y N 408 
TYR CG  CD2  sing Y N 409 
TYR CD1 CE1  sing Y N 410 
TYR CD1 HD1  sing N N 411 
TYR CD2 CE2  doub Y N 412 
TYR CD2 HD2  sing N N 413 
TYR CE1 CZ   doub Y N 414 
TYR CE1 HE1  sing N N 415 
TYR CE2 CZ   sing Y N 416 
TYR CE2 HE2  sing N N 417 
TYR CZ  OH   sing N N 418 
TYR OH  HH   sing N N 419 
TYR OXT HXT  sing N N 420 
VAL N   CA   sing N N 421 
VAL N   H    sing N N 422 
VAL N   H2   sing N N 423 
VAL CA  C    sing N N 424 
VAL CA  CB   sing N N 425 
VAL CA  HA   sing N N 426 
VAL C   O    doub N N 427 
VAL C   OXT  sing N N 428 
VAL CB  CG1  sing N N 429 
VAL CB  CG2  sing N N 430 
VAL CB  HB   sing N N 431 
VAL CG1 HG11 sing N N 432 
VAL CG1 HG12 sing N N 433 
VAL CG1 HG13 sing N N 434 
VAL CG2 HG21 sing N N 435 
VAL CG2 HG22 sing N N 436 
VAL CG2 HG23 sing N N 437 
VAL OXT HXT  sing N N 438 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ETB 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013486 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007481 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006759 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201  10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
I 53 53 20.1470 4.3470  18.9947 0.3814  7.5137 27.7660 2.2735 66.8776 3.6514   
N 7  7  12.2220 0.0057  3.1346  9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870  5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P 15 15 6.4348  1.9067  4.1793  27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S 16 16 6.9054  1.4679  5.2035  22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 1   ? -65.243 0.215   33.268  1   65.08  ? 171 GLY D N   1 
ATOM   2    C CA  . GLY A 1 1   ? -64.781 1.616   33.292  1   65.23  ? 171 GLY D CA  1 
ATOM   3    C C   . GLY A 1 1   ? -63.381 1.736   32.695  1   62.49  ? 171 GLY D C   1 
ATOM   4    O O   . GLY A 1 1   ? -62.978 0.903   31.882  1   61.72  ? 171 GLY D O   1 
ATOM   5    N N   . VAL A 1 2   ? -62.647 2.759   33.142  1   60.78  ? 172 VAL D N   1 
ATOM   6    C CA  . VAL A 1 2   ? -61.347 3.082   32.579  1   59.87  ? 172 VAL D CA  1 
ATOM   7    C C   . VAL A 1 2   ? -60.285 2.146   33.161  1   60.28  ? 172 VAL D C   1 
ATOM   8    O O   . VAL A 1 2   ? -59.16  2.048   32.659  1   58.52  ? 172 VAL D O   1 
ATOM   9    C CB  . VAL A 1 2   ? -61.013 4.571   32.784  1   59.49  ? 172 VAL D CB  1 
ATOM   10   C CG1 . VAL A 1 2   ? -60.585 4.876   34.218  1   58.48  ? 172 VAL D CG1 1 
ATOM   11   C CG2 . VAL A 1 2   ? -60.002 5.083   31.763  1   56.95  ? 172 VAL D CG2 1 
ATOM   12   N N   . ASN A 1 3   ? -60.667 1.428   34.22   1   63.48  ? 173 ASN D N   1 
ATOM   13   C CA  . ASN A 1 3   ? -59.795 0.425   34.815  1   62.58  ? 173 ASN D CA  1 
ATOM   14   C C   . ASN A 1 3   ? -59.616 -0.741  33.841  1   59.71  ? 173 ASN D C   1 
ATOM   15   O O   . ASN A 1 3   ? -58.665 -1.502  33.979  1   59.07  ? 173 ASN D O   1 
ATOM   16   C CB  . ASN A 1 3   ? -60.272 0.069   36.222  1   66.55  ? 173 ASN D CB  1 
ATOM   17   C CG  . ASN A 1 3   ? -60.419 1.268   37.146  1   72.03  ? 173 ASN D CG  1 
ATOM   18   O OD1 . ASN A 1 3   ? -59.901 2.372   36.897  1   73.51  ? 173 ASN D OD1 1 
ATOM   19   N ND2 . ASN A 1 3   ? -61.113 1.07    38.257  1   74.85  ? 173 ASN D ND2 1 
ATOM   20   N N   . GLU A 1 4   ? -60.514 -0.846  32.846  1   60.2   ? 174 GLU D N   1 
ATOM   21   C CA  . GLU A 1 4   ? -60.484 -1.862  31.797  1   59.7   ? 174 GLU D CA  1 
ATOM   22   C C   . GLU A 1 4   ? -59.963 -1.267  30.485  1   59.07  ? 174 GLU D C   1 
ATOM   23   O O   . GLU A 1 4   ? -59.988 -1.93   29.439  1   58.72  ? 174 GLU D O   1 
ATOM   24   C CB  . GLU A 1 4   ? -61.854 -2.528  31.622  1   61.28  ? 174 GLU D CB  1 
ATOM   25   C CG  . GLU A 1 4   ? -62.1   -3.698  32.569  1   60.8   ? 174 GLU D CG  1 
ATOM   26   C CD  . GLU A 1 4   ? -63.537 -4.061  32.912  1   63.92  ? 174 GLU D CD  1 
ATOM   27   O OE1 . GLU A 1 4   ? -64.447 -4.1    32.059  1   66.92  ? 174 GLU D OE1 1 
ATOM   28   O OE2 . GLU A 1 4   ? -63.742 -4.326  34.1    1   63.59  ? 174 GLU D OE2 1 
ATOM   29   N N   . VAL A 1 5   ? -59.463 -0.025  30.573  1   57.7   ? 175 VAL D N   1 
ATOM   30   C CA  . VAL A 1 5   ? -58.911 0.725   29.452  1   57.89  ? 175 VAL D CA  1 
ATOM   31   C C   . VAL A 1 5   ? -59.623 0.342   28.154  1   59.4   ? 175 VAL D C   1 
ATOM   32   O O   . VAL A 1 5   ? -59.043 -0.331  27.296  1   58.87  ? 175 VAL D O   1 
ATOM   33   C CB  . VAL A 1 5   ? -57.386 0.536   29.368  1   54.72  ? 175 VAL D CB  1 
ATOM   34   C CG1 . VAL A 1 5   ? -56.671 1.422   30.383  1   55.9   ? 175 VAL D CG1 1 
ATOM   35   C CG2 . VAL A 1 5   ? -56.979 -0.913  29.562  1   51.6   ? 175 VAL D CG2 1 
ATOM   36   N N   . PRO A 1 6   ? -60.906 0.754   28.001  1   60.52  ? 176 PRO D N   1 
ATOM   37   C CA  . PRO A 1 6   ? -61.711 0.448   26.815  1   62.26  ? 176 PRO D CA  1 
ATOM   38   C C   . PRO A 1 6   ? -61.07  0.825   25.485  1   63.43  ? 176 PRO D C   1 
ATOM   39   O O   . PRO A 1 6   ? -61.16  0.077   24.523  1   66.24  ? 176 PRO D O   1 
ATOM   40   C CB  . PRO A 1 6   ? -62.99  1.268   27.018  1   64.83  ? 176 PRO D CB  1 
ATOM   41   C CG  . PRO A 1 6   ? -63.067 1.523   28.512  1   63.84  ? 176 PRO D CG  1 
ATOM   42   C CD  . PRO A 1 6   ? -61.642 1.54    29.003  1   60.84  ? 176 PRO D CD  1 
ATOM   43   N N   . ASP A 1 7   ? -60.456 2.01    25.421  1   63.69  ? 177 ASP D N   1 
ATOM   44   C CA  . ASP A 1 7   ? -59.959 2.567   24.171  1   64.61  ? 177 ASP D CA  1 
ATOM   45   C C   . ASP A 1 7   ? -58.615 1.936   23.769  1   63.74  ? 177 ASP D C   1 
ATOM   46   O O   . ASP A 1 7   ? -58.153 2.145   22.648  1   65.99  ? 177 ASP D O   1 
ATOM   47   C CB  . ASP A 1 7   ? -59.963 4.094   24.201  1   64.6   ? 177 ASP D CB  1 
ATOM   48   C CG  . ASP A 1 7   ? -61.326 4.784   24.117  1   67.72  ? 177 ASP D CG  1 
ATOM   49   O OD1 . ASP A 1 7   ? -62.354 4.08    24.112  1   69.44  ? 177 ASP D OD1 1 
ATOM   50   O OD2 . ASP A 1 7   ? -61.374 6.031   24.042  1   68.47  ? 177 ASP D OD2 1 
ATOM   51   N N   . TYR A 1 8   ? -57.969 1.174   24.668  1   60.12  ? 178 TYR D N   1 
ATOM   52   C CA  . TYR A 1 8   ? -56.6   0.74    24.426  1   57.32  ? 178 TYR D CA  1 
ATOM   53   C C   . TYR A 1 8   ? -56.415 -0.767  24.609  1   60.2   ? 178 TYR D C   1 
ATOM   54   O O   . TYR A 1 8   ? -55.322 -1.26   24.349  1   63.19  ? 178 TYR D O   1 
ATOM   55   C CB  . TYR A 1 8   ? -55.595 1.47    25.326  1   52.12  ? 178 TYR D CB  1 
ATOM   56   C CG  . TYR A 1 8   ? -55.627 2.988   25.244  1   52.52  ? 178 TYR D CG  1 
ATOM   57   C CD1 . TYR A 1 8   ? -54.865 3.683   24.313  1   52.27  ? 178 TYR D CD1 1 
ATOM   58   C CD2 . TYR A 1 8   ? -56.433 3.726   26.098  1   53.14  ? 178 TYR D CD2 1 
ATOM   59   C CE1 . TYR A 1 8   ? -54.905 5.065   24.23   1   53.12  ? 178 TYR D CE1 1 
ATOM   60   C CE2 . TYR A 1 8   ? -56.483 5.107   26.017  1   54.4   ? 178 TYR D CE2 1 
ATOM   61   C CZ  . TYR A 1 8   ? -55.712 5.787   25.095  1   54.8   ? 178 TYR D CZ  1 
ATOM   62   O OH  . TYR A 1 8   ? -55.791 7.164   25.092  1   58.18  ? 178 TYR D OH  1 
ATOM   63   N N   . HIS A 1 9   ? -57.463 -1.508  25.006  1   63.51  ? 179 HIS D N   1 
ATOM   64   C CA  . HIS A 1 9   ? -57.338 -2.935  25.296  1   62.87  ? 179 HIS D CA  1 
ATOM   65   C C   . HIS A 1 9   ? -56.944 -3.751  24.061  1   62.6   ? 179 HIS D C   1 
ATOM   66   O O   . HIS A 1 9   ? -56.346 -4.817  24.196  1   62.32  ? 179 HIS D O   1 
ATOM   67   C CB  . HIS A 1 9   ? -58.537 -3.506  26.078  1   67.19  ? 179 HIS D CB  1 
ATOM   68   C CG  . HIS A 1 9   ? -59.818 -3.725  25.322  1   74.44  ? 179 HIS D CG  1 
ATOM   69   N ND1 . HIS A 1 9   ? -60.031 -4.727  24.395  1   76.52  ? 179 HIS D ND1 1 
ATOM   70   C CD2 . HIS A 1 9   ? -60.981 -3.054  25.396  1   79.46  ? 179 HIS D CD2 1 
ATOM   71   C CE1 . HIS A 1 9   ? -61.255 -4.633  23.904  1   81.06  ? 179 HIS D CE1 1 
ATOM   72   N NE2 . HIS A 1 9   ? -61.858 -3.636  24.514  1   83.77  ? 179 HIS D NE2 1 
ATOM   73   N N   . GLU A 1 10  ? -57.294 -3.284  22.857  1   64.5   ? 180 GLU D N   1 
ATOM   74   C CA  . GLU A 1 10  ? -56.942 -4.05   21.672  1   67.17  ? 180 GLU D CA  1 
ATOM   75   C C   . GLU A 1 10  ? -55.526 -3.724  21.208  1   65.26  ? 180 GLU D C   1 
ATOM   76   O O   . GLU A 1 10  ? -54.768 -4.634  20.874  1   65.7   ? 180 GLU D O   1 
ATOM   77   C CB  . GLU A 1 10  ? -57.981 -3.83   20.583  1   74.48  ? 180 GLU D CB  1 
ATOM   78   C CG  . GLU A 1 10  ? -59.378 -4.242  21.034  1   82.08  ? 180 GLU D CG  1 
ATOM   79   C CD  . GLU A 1 10  ? -60.373 -3.957  19.936  1   91.78  ? 180 GLU D CD  1 
ATOM   80   O OE1 . GLU A 1 10  ? -61.441 -3.375  20.233  1   101.57 ? 180 GLU D OE1 1 
ATOM   81   O OE2 . GLU A 1 10  ? -60.019 -4.276  18.774  1   90.41  ? 180 GLU D OE2 1 
ATOM   82   N N   . ASP A 1 11  ? -55.189 -2.425  21.205  1   63.67  ? 181 ASP D N   1 
ATOM   83   C CA  . ASP A 1 11  ? -53.88  -1.942  20.781  1   59.36  ? 181 ASP D CA  1 
ATOM   84   C C   . ASP A 1 11  ? -52.789 -2.625  21.592  1   55.27  ? 181 ASP D C   1 
ATOM   85   O O   . ASP A 1 11  ? -51.756 -3.008  21.039  1   53.63  ? 181 ASP D O   1 
ATOM   86   C CB  . ASP A 1 11  ? -53.728 -0.447  20.996  1   59.74  ? 181 ASP D CB  1 
ATOM   87   C CG  . ASP A 1 11  ? -54.378 0.424   19.943  1   63.38  ? 181 ASP D CG  1 
ATOM   88   O OD1 . ASP A 1 11  ? -55.014 -0.138  19.048  1   68.12  ? 181 ASP D OD1 1 
ATOM   89   O OD2 . ASP A 1 11  ? -54.216 1.655   20.004  1   64.53  ? 181 ASP D OD2 1 
ATOM   90   N N   . ILE A 1 12  ? -53.048 -2.707  22.908  1   51.26  ? 182 ILE D N   1 
ATOM   91   C CA  . ILE A 1 12  ? -52.205 -3.306  23.924  1   48.32  ? 182 ILE D CA  1 
ATOM   92   C C   . ILE A 1 12  ? -52.047 -4.802  23.638  1   50.39  ? 182 ILE D C   1 
ATOM   93   O O   . ILE A 1 12  ? -50.957 -5.35   23.803  1   49.02  ? 182 ILE D O   1 
ATOM   94   C CB  . ILE A 1 12  ? -52.829 -3.066  25.317  1   46.45  ? 182 ILE D CB  1 
ATOM   95   C CG1 . ILE A 1 12  ? -52.787 -1.599  25.751  1   46.16  ? 182 ILE D CG1 1 
ATOM   96   C CG2 . ILE A 1 12  ? -52.235 -3.982  26.394  1   43.8   ? 182 ILE D CG2 1 
ATOM   97   C CD1 . ILE A 1 12  ? -53.51  -1.318  27.061  1   44.81  ? 182 ILE D CD1 1 
ATOM   98   N N   . HIS A 1 13  ? -53.156 -5.47   23.273  1   53.45  ? 183 HIS D N   1 
ATOM   99   C CA  . HIS A 1 13  ? -53.163 -6.896  22.996  1   52.72  ? 183 HIS D CA  1 
ATOM   100  C C   . HIS A 1 13  ? -52.33  -7.172  21.739  1   51.19  ? 183 HIS D C   1 
ATOM   101  O O   . HIS A 1 13  ? -51.506 -8.078  21.726  1   50.15  ? 183 HIS D O   1 
ATOM   102  C CB  . HIS A 1 13  ? -54.607 -7.403  22.974  1   58.94  ? 183 HIS D CB  1 
ATOM   103  C CG  . HIS A 1 13  ? -54.762 -8.829  22.537  1   61.59  ? 183 HIS D CG  1 
ATOM   104  N ND1 . HIS A 1 13  ? -54.759 -9.883  23.421  1   59.18  ? 183 HIS D ND1 1 
ATOM   105  C CD2 . HIS A 1 13  ? -54.93  -9.357  21.313  1   62.17  ? 183 HIS D CD2 1 
ATOM   106  C CE1 . HIS A 1 13  ? -54.911 -11.008 22.739  1   63.3   ? 183 HIS D CE1 1 
ATOM   107  N NE2 . HIS A 1 13  ? -55.012 -10.711 21.458  1   64.13  ? 183 HIS D NE2 1 
ATOM   108  N N   . THR A 1 14  ? -52.506 -6.364  20.69   1   50.45  ? 184 THR D N   1 
ATOM   109  C CA  . THR A 1 14  ? -51.644 -6.465  19.522  1   49.88  ? 184 THR D CA  1 
ATOM   110  C C   . THR A 1 14  ? -50.175 -6.422  19.945  1   47.08  ? 184 THR D C   1 
ATOM   111  O O   . THR A 1 14  ? -49.409 -7.289  19.559  1   46.81  ? 184 THR D O   1 
ATOM   112  C CB  . THR A 1 14  ? -51.998 -5.368  18.511  1   51.65  ? 184 THR D CB  1 
ATOM   113  O OG1 . THR A 1 14  ? -53.275 -5.728  17.986  1   53.28  ? 184 THR D OG1 1 
ATOM   114  C CG2 . THR A 1 14  ? -50.989 -5.216  17.385  1   51.24  ? 184 THR D CG2 1 
ATOM   115  N N   . TYR A 1 15  ? -49.79  -5.39   20.703  1   46.29  ? 185 TYR D N   1 
ATOM   116  C CA  . TYR A 1 15  ? -48.402 -5.124  21.034  1   45.24  ? 185 TYR D CA  1 
ATOM   117  C C   . TYR A 1 15  ? -47.844 -6.276  21.862  1   44.33  ? 185 TYR D C   1 
ATOM   118  O O   . TYR A 1 15  ? -46.721 -6.718  21.644  1   43.87  ? 185 TYR D O   1 
ATOM   119  C CB  . TYR A 1 15  ? -48.304 -3.807  21.809  1   46.06  ? 185 TYR D CB  1 
ATOM   120  C CG  . TYR A 1 15  ? -46.885 -3.389  22.165  1   46.51  ? 185 TYR D CG  1 
ATOM   121  C CD1 . TYR A 1 15  ? -45.981 -3.051  21.167  1   48.51  ? 185 TYR D CD1 1 
ATOM   122  C CD2 . TYR A 1 15  ? -46.441 -3.344  23.481  1   46.06  ? 185 TYR D CD2 1 
ATOM   123  C CE1 . TYR A 1 15  ? -44.683 -2.667  21.461  1   48.14  ? 185 TYR D CE1 1 
ATOM   124  C CE2 . TYR A 1 15  ? -45.141 -2.967  23.793  1   46.3   ? 185 TYR D CE2 1 
ATOM   125  C CZ  . TYR A 1 15  ? -44.26  -2.618  22.778  1   48.09  ? 185 TYR D CZ  1 
ATOM   126  O OH  . TYR A 1 15  ? -42.961 -2.245  23.015  1   48.45  ? 185 TYR D OH  1 
ATOM   127  N N   . LEU A 1 16  ? -48.608 -6.7    22.86   1   44.24  ? 186 LEU D N   1 
ATOM   128  C CA  . LEU A 1 16  ? -48.142 -7.77   23.768  1   43.68  ? 186 LEU D CA  1 
ATOM   129  C C   . LEU A 1 16  ? -47.921 -9.048  22.963  1   45.06  ? 186 LEU D C   1 
ATOM   130  O O   . LEU A 1 16  ? -47.008 -9.809  23.288  1   44.22  ? 186 LEU D O   1 
ATOM   131  C CB  . LEU A 1 16  ? -49.203 -7.965  24.845  1   43.77  ? 186 LEU D CB  1 
ATOM   132  C CG  . LEU A 1 16  ? -49.206 -6.966  26.002  1   42.13  ? 186 LEU D CG  1 
ATOM   133  C CD1 . LEU A 1 16  ? -50.016 -7.568  27.129  1   40.39  ? 186 LEU D CD1 1 
ATOM   134  C CD2 . LEU A 1 16  ? -47.796 -6.646  26.451  1   41.86  ? 186 LEU D CD2 1 
ATOM   135  N N   . ARG A 1 17  ? -48.702 -9.347  21.985  1   47.93  ? 187 ARG D N   1 
ATOM   136  C CA  . ARG A 1 17  ? -48.551 -10.573 21.157  1   50.11  ? 187 ARG D CA  1 
ATOM   137  C C   . ARG A 1 17  ? -47.302 -10.446 20.278  1   51.74  ? 187 ARG D C   1 
ATOM   138  O O   . ARG A 1 17  ? -46.72  -11.482 19.939  1   56.53  ? 187 ARG D O   1 
ATOM   139  C CB  . ARG A 1 17  ? -49.844 -10.758 20.358  1   49.52  ? 187 ARG D CB  1 
ATOM   140  C CG  . ARG A 1 17  ? -51.092 -11.078 21.164  1   48.85  ? 187 ARG D CG  1 
ATOM   141  C CD  . ARG A 1 17  ? -51.361 -12.562 21.286  1   47.91  ? 187 ARG D CD  1 
ATOM   142  N NE  . ARG A 1 17  ? -51.201 -13.272 20.015  1   48.61  ? 187 ARG D NE  1 
ATOM   143  C CZ  . ARG A 1 17  ? -52.195 -13.867 19.381  1   49.98  ? 187 ARG D CZ  1 
ATOM   144  N NH1 . ARG A 1 17  ? -51.98  -14.439 18.213  1   50.73  ? 187 ARG D NH1 1 
ATOM   145  N NH2 . ARG A 1 17  ? -53.399 -13.892 19.92   1   48.55  ? 187 ARG D NH2 1 
ATOM   146  N N   . GLU A 1 18  ? -46.934 -9.131  19.927  1   49.77  ? 188 GLU D N   1 
ATOM   147  C CA  . GLU A 1 18  ? -45.694 -8.943  19.139  1   50.03  ? 188 GLU D CA  1 
ATOM   148  C C   . GLU A 1 18  ? -44.508 -9.046  20.082  1   49.37  ? 188 GLU D C   1 
ATOM   149  O O   . GLU A 1 18  ? -43.52  -9.702  19.726  1   49.37  ? 188 GLU D O   1 
ATOM   150  C CB  . GLU A 1 18  ? -45.569 -7.554  18.525  1   54.18  ? 188 GLU D CB  1 
ATOM   151  C CG  . GLU A 1 18  ? -46.759 -7.155  17.66   1   59.42  ? 188 GLU D CG  1 
ATOM   152  C CD  . GLU A 1 18  ? -46.612 -5.775  17.049  1   68.55  ? 188 GLU D CD  1 
ATOM   153  O OE1 . GLU A 1 18  ? -47.377 -5.454  16.118  1   64.77  ? 188 GLU D OE1 1 
ATOM   154  O OE2 . GLU A 1 18  ? -45.727 -5.023  17.505  1   71.19  ? 188 GLU D OE2 1 
ATOM   155  N N   . MET A 1 19  ? -44.618 -8.404  21.242  1   47.59  ? 189 MET D N   1 
ATOM   156  C CA  . MET A 1 19  ? -43.527 -8.427  22.202  1   45.26  ? 189 MET D CA  1 
ATOM   157  C C   . MET A 1 19  ? -43.285 -9.846  22.723  1   47.06  ? 189 MET D C   1 
ATOM   158  O O   . MET A 1 19  ? -42.136 -10.214 22.981  1   46.28  ? 189 MET D O   1 
ATOM   159  C CB  . MET A 1 19  ? -43.8   -7.455  23.353  1   44.33  ? 189 MET D CB  1 
ATOM   160  C CG  . MET A 1 19  ? -43.798 -6.005  22.898  1   49.24  ? 189 MET D CG  1 
ATOM   161  S SD  . MET A 1 19  ? -42.271 -5.411  22.134  1   51.21  ? 189 MET D SD  1 
ATOM   162  C CE  . MET A 1 19  ? -41.106 -5.708  23.485  1   48.82  ? 189 MET D CE  1 
ATOM   163  N N   . GLU A 1 20  ? -44.36  -10.643 22.871  1   48.4   ? 190 GLU D N   1 
ATOM   164  C CA  . GLU A 1 20  ? -44.251 -12.002 23.388  1   45.2   ? 190 GLU D CA  1 
ATOM   165  C C   . GLU A 1 20  ? -43.369 -12.831 22.46   1   44.58  ? 190 GLU D C   1 
ATOM   166  O O   . GLU A 1 20  ? -42.613 -13.676 22.937  1   44.46  ? 190 GLU D O   1 
ATOM   167  C CB  . GLU A 1 20  ? -45.586 -12.696 23.673  1   44.11  ? 190 GLU D CB  1 
ATOM   168  C CG  . GLU A 1 20  ? -46.264 -13.328 22.463  1   44.23  ? 190 GLU D CG  1 
ATOM   169  C CD  . GLU A 1 20  ? -47.519 -14.119 22.805  1   44.58  ? 190 GLU D CD  1 
ATOM   170  O OE1 . GLU A 1 20  ? -47.578 -14.659 23.941  1   40.16  ? 190 GLU D OE1 1 
ATOM   171  O OE2 . GLU A 1 20  ? -48.451 -14.171 21.943  1   45.88  ? 190 GLU D OE2 1 
ATOM   172  N N   . VAL A 1 21  ? -43.464 -12.561 21.149  1   43.15  ? 191 VAL D N   1 
ATOM   173  C CA  . VAL A 1 21  ? -42.62  -13.222 20.17   1   43.11  ? 191 VAL D CA  1 
ATOM   174  C C   . VAL A 1 21  ? -41.176 -12.764 20.351  1   45.09  ? 191 VAL D C   1 
ATOM   175  O O   . VAL A 1 21  ? -40.265 -13.572 20.289  1   46.3   ? 191 VAL D O   1 
ATOM   176  C CB  . VAL A 1 21  ? -43.145 -12.972 18.741  1   41.87  ? 191 VAL D CB  1 
ATOM   177  C CG1 . VAL A 1 21  ? -42.092 -13.13  17.646  1   39.72  ? 191 VAL D CG1 1 
ATOM   178  C CG2 . VAL A 1 21  ? -44.388 -13.791 18.454  1   40.46  ? 191 VAL D CG2 1 
ATOM   179  N N   . LYS A 1 22  ? -40.969 -11.466 20.577  1   51.28  ? 192 LYS D N   1 
ATOM   180  C CA  . LYS A 1 22  ? -39.633 -10.895 20.712  1   59.62  ? 192 LYS D CA  1 
ATOM   181  C C   . LYS A 1 22  ? -38.939 -11.326 22.013  1   57.32  ? 192 LYS D C   1 
ATOM   182  O O   . LYS A 1 22  ? -37.74  -11.606 22.007  1   56.77  ? 192 LYS D O   1 
ATOM   183  C CB  . LYS A 1 22  ? -39.656 -9.372  20.519  1   66.66  ? 192 LYS D CB  1 
ATOM   184  C CG  . LYS A 1 22  ? -39.818 -8.963  19.046  1   75.81  ? 192 LYS D CG  1 
ATOM   185  C CD  . LYS A 1 22  ? -39.771 -7.485  18.664  1   89.36  ? 192 LYS D CD  1 
ATOM   186  C CE  . LYS A 1 22  ? -38.409 -6.823  18.671  1   96.06  ? 192 LYS D CE  1 
ATOM   187  N NZ  . LYS A 1 22  ? -37.376 -7.541  17.908  1   88.65  ? 192 LYS D NZ  1 
ATOM   188  N N   . CYS A 1 23  ? -39.683 -11.375 23.128  1   54.75  ? 193 CYS D N   1 
ATOM   189  C CA  . CYS A 1 23  ? -39.108 -11.74  24.418  1   54.09  ? 193 CYS D CA  1 
ATOM   190  C C   . CYS A 1 23  ? -38.96  -13.253 24.602  1   52.82  ? 193 CYS D C   1 
ATOM   191  O O   . CYS A 1 23  ? -38.83  -13.694 25.743  1   48.18  ? 193 CYS D O   1 
ATOM   192  C CB  . CYS A 1 23  ? -39.982 -11.291 25.585  1   51.14  ? 193 CYS D CB  1 
ATOM   193  S SG  . CYS A 1 23  ? -39.983 -9.5    25.832  1   58.67  ? 193 CYS D SG  1 
ATOM   194  N N   . LYS A 1 24  ? -38.98  -14.039 23.514  1   52.45  ? 194 LYS D N   1 
ATOM   195  C CA  . LYS A 1 24  ? -39.199 -15.475 23.642  1   54.16  ? 194 LYS D CA  1 
ATOM   196  C C   . LYS A 1 24  ? -37.868 -16.186 23.88   1   55.32  ? 194 LYS D C   1 
ATOM   197  O O   . LYS A 1 24  ? -36.918 -15.88  23.159  1   60.31  ? 194 LYS D O   1 
ATOM   198  C CB  . LYS A 1 24  ? -39.839 -16.099 22.397  1   56.09  ? 194 LYS D CB  1 
ATOM   199  C CG  . LYS A 1 24  ? -40.74  -17.277 22.757  1   60.4   ? 194 LYS D CG  1 
ATOM   200  C CD  . LYS A 1 24  ? -40.82  -18.364 21.691  1   65.99  ? 194 LYS D CD  1 
ATOM   201  C CE  . LYS A 1 24  ? -41.727 -19.474 22.147  1   63.27  ? 194 LYS D CE  1 
ATOM   202  N NZ  . LYS A 1 24  ? -42.142 -20.317 21.029  1   56.27  ? 194 LYS D NZ  1 
ATOM   203  N N   . PRO A 1 25  ? -37.76  -17.129 24.87   1   48.84  ? 195 PRO D N   1 
ATOM   204  C CA  . PRO A 1 25  ? -36.522 -17.872 25.13   1   42.38  ? 195 PRO D CA  1 
ATOM   205  C C   . PRO A 1 25  ? -36.291 -18.829 23.974  1   41.66  ? 195 PRO D C   1 
ATOM   206  O O   . PRO A 1 25  ? -37.227 -19.075 23.219  1   45.27  ? 195 PRO D O   1 
ATOM   207  C CB  . PRO A 1 25  ? -36.813 -18.641 26.421  1   43.15  ? 195 PRO D CB  1 
ATOM   208  C CG  . PRO A 1 25  ? -38.047 -17.983 27.015  1   43.74  ? 195 PRO D CG  1 
ATOM   209  C CD  . PRO A 1 25  ? -38.83  -17.524 25.808  1   47.91  ? 195 PRO D CD  1 
ATOM   210  N N   . LYS A 1 26  ? -35.086 -19.388 23.888  1   40.41  ? 196 LYS D N   1 
ATOM   211  C CA  . LYS A 1 26  ? -34.748 -20.344 22.809  1   47.22  ? 196 LYS D CA  1 
ATOM   212  C C   . LYS A 1 26  ? -35.214 -21.754 23.193  1   47.8   ? 196 LYS D C   1 
ATOM   213  O O   . LYS A 1 26  ? -34.7   -22.301 24.17   1   48.83  ? 196 LYS D O   1 
ATOM   214  C CB  . LYS A 1 26  ? -33.241 -20.293 22.55   1   51.2   ? 196 LYS D CB  1 
ATOM   215  C CG  . LYS A 1 26  ? -32.78  -19.283 21.516  1   59.6   ? 196 LYS D CG  1 
ATOM   216  C CD  . LYS A 1 26  ? -31.382 -18.749 21.796  1   65.45  ? 196 LYS D CD  1 
ATOM   217  C CE  . LYS A 1 26  ? -31.398 -17.29  22.112  1   68.94  ? 196 LYS D CE  1 
ATOM   218  N NZ  . LYS A 1 26  ? -30.108 -16.831 22.631  1   69.41  ? 196 LYS D NZ  1 
ATOM   219  N N   . VAL A 1 27  ? -36.158 -22.312 22.436  1   49.17  ? 197 VAL D N   1 
ATOM   220  C CA  . VAL A 1 27  ? -36.664 -23.656 22.713  1   54.12  ? 197 VAL D CA  1 
ATOM   221  C C   . VAL A 1 27  ? -35.489 -24.628 22.833  1   50.45  ? 197 VAL D C   1 
ATOM   222  O O   . VAL A 1 27  ? -34.645 -24.67  21.948  1   50.92  ? 197 VAL D O   1 
ATOM   223  C CB  . VAL A 1 27  ? -37.643 -24.107 21.605  1   60.55  ? 197 VAL D CB  1 
ATOM   224  C CG1 . VAL A 1 27  ? -38.38  -25.398 21.958  1   62.6   ? 197 VAL D CG1 1 
ATOM   225  C CG2 . VAL A 1 27  ? -38.645 -23.009 21.247  1   62.79  ? 197 VAL D CG2 1 
ATOM   226  N N   . GLY A 1 28  ? -35.434 -25.405 23.922  1   49.91  ? 198 GLY D N   1 
ATOM   227  C CA  . GLY A 1 28  ? -34.359 -26.372 24.143  1   53.38  ? 198 GLY D CA  1 
ATOM   228  C C   . GLY A 1 28  ? -32.957 -25.751 24.26   1   54.25  ? 198 GLY D C   1 
ATOM   229  O O   . GLY A 1 28  ? -31.981 -26.356 23.817  1   57.64  ? 198 GLY D O   1 
ATOM   230  N N   . TYR A 1 29  ? -32.86  -24.545 24.855  1   45.68  ? 199 TYR D N   1 
ATOM   231  C CA  . TYR A 1 29  ? -31.607 -23.976 25.317  1   38.88  ? 199 TYR D CA  1 
ATOM   232  C C   . TYR A 1 29  ? -30.977 -24.955 26.31   1   38.41  ? 199 TYR D C   1 
ATOM   233  O O   . TYR A 1 29  ? -29.77  -24.939 26.53   1   38.95  ? 199 TYR D O   1 
ATOM   234  C CB  . TYR A 1 29  ? -31.749 -22.564 25.921  1   35.77  ? 199 TYR D CB  1 
ATOM   235  C CG  . TYR A 1 29  ? -32.438 -22.487 27.28   1   32.45  ? 199 TYR D CG  1 
ATOM   236  C CD1 . TYR A 1 29  ? -31.793 -22.919 28.439  1   33.07  ? 199 TYR D CD1 1 
ATOM   237  C CD2 . TYR A 1 29  ? -33.732 -22.02  27.41   1   30.13  ? 199 TYR D CD2 1 
ATOM   238  C CE1 . TYR A 1 29  ? -32.394 -22.879 29.685  1   31.82  ? 199 TYR D CE1 1 
ATOM   239  C CE2 . TYR A 1 29  ? -34.345 -21.964 28.652  1   30.76  ? 199 TYR D CE2 1 
ATOM   240  C CZ  . TYR A 1 29  ? -33.68  -22.387 29.795  1   32.47  ? 199 TYR D CZ  1 
ATOM   241  O OH  . TYR A 1 29  ? -34.286 -22.362 31.031  1   35.06  ? 199 TYR D OH  1 
ATOM   242  N N   . MET A 1 30  ? -31.783 -25.828 26.91   1   37.04  ? 200 MET D N   1 
ATOM   243  C CA  . MET A 1 30  ? -31.198 -26.684 27.914  1   39.3   ? 200 MET D CA  1 
ATOM   244  C C   . MET A 1 30  ? -30.251 -27.7   27.27   1   42.52  ? 200 MET D C   1 
ATOM   245  O O   . MET A 1 30  ? -29.325 -28.209 27.901  1   43.22  ? 200 MET D O   1 
ATOM   246  C CB  . MET A 1 30  ? -32.305 -27.32  28.755  1   42.18  ? 200 MET D CB  1 
ATOM   247  C CG  . MET A 1 30  ? -31.838 -27.812 30.109  1   44.04  ? 200 MET D CG  1 
ATOM   248  S SD  . MET A 1 30  ? -31.48  -26.37  31.126  1   47.95  ? 200 MET D SD  1 
ATOM   249  C CE  . MET A 1 30  ? -33.164 -25.799 31.383  1   48.35  ? 200 MET D CE  1 
ATOM   250  N N   . LYS A 1 31  ? -30.468 -28.034 26.004  1   45.97  ? 201 LYS D N   1 
ATOM   251  C CA  . LYS A 1 31  ? -29.564 -29     25.391  1   50.54  ? 201 LYS D CA  1 
ATOM   252  C C   . LYS A 1 31  ? -28.168 -28.389 25.229  1   50.17  ? 201 LYS D C   1 
ATOM   253  O O   . LYS A 1 31  ? -27.172 -29.106 25.177  1   51.64  ? 201 LYS D O   1 
ATOM   254  C CB  . LYS A 1 31  ? -30.1   -29.531 24.054  1   55.71  ? 201 LYS D CB  1 
ATOM   255  C CG  . LYS A 1 31  ? -31.542 -29.998 24.077  1   59.62  ? 201 LYS D CG  1 
ATOM   256  C CD  . LYS A 1 31  ? -32.183 -29.973 22.694  1   65.96  ? 201 LYS D CD  1 
ATOM   257  C CE  . LYS A 1 31  ? -31.706 -31.029 21.745  1   78.53  ? 201 LYS D CE  1 
ATOM   258  N NZ  . LYS A 1 31  ? -31.902 -32.396 22.242  1   79.89  ? 201 LYS D NZ  1 
ATOM   259  N N   . LYS A 1 32  ? -28.091 -27.056 25.13   1   49.04  ? 202 LYS D N   1 
ATOM   260  C CA  . LYS A 1 32  ? -26.83  -26.371 24.889  1   49.41  ? 202 LYS D CA  1 
ATOM   261  C C   . LYS A 1 32  ? -26.132 -26.045 26.205  1   44.76  ? 202 LYS D C   1 
ATOM   262  O O   . LYS A 1 32  ? -24.964 -25.687 26.199  1   44.22  ? 202 LYS D O   1 
ATOM   263  C CB  . LYS A 1 32  ? -27.087 -25.131 24.029  1   55.6   ? 202 LYS D CB  1 
ATOM   264  C CG  . LYS A 1 32  ? -27.703 -25.428 22.643  1   60.73  ? 202 LYS D CG  1 
ATOM   265  C CD  . LYS A 1 32  ? -26.93  -26.311 21.667  1   66.54  ? 202 LYS D CD  1 
ATOM   266  C CE  . LYS A 1 32  ? -25.681 -25.703 21.062  1   75.9   ? 202 LYS D CE  1 
ATOM   267  N NZ  . LYS A 1 32  ? -24.809 -26.683 20.388  1   74.91  ? 202 LYS D NZ  1 
ATOM   268  N N   . GLN A 1 33  ? -26.859 -26.193 27.318  1   41.9   ? 203 GLN D N   1 
ATOM   269  C CA  . GLN A 1 33  ? -26.367 -25.964 28.673  1   37.86  ? 203 GLN D CA  1 
ATOM   270  C C   . GLN A 1 33  ? -25.683 -27.224 29.186  1   39.03  ? 203 GLN D C   1 
ATOM   271  O O   . GLN A 1 33  ? -26.357 -28.147 29.655  1   39.12  ? 203 GLN D O   1 
ATOM   272  C CB  . GLN A 1 33  ? -27.519 -25.685 29.643  1   35.58  ? 203 GLN D CB  1 
ATOM   273  C CG  . GLN A 1 33  ? -28.082 -24.271 29.597  1   33.55  ? 203 GLN D CG  1 
ATOM   274  C CD  . GLN A 1 33  ? -27.126 -23.287 30.225  1   34.83  ? 203 GLN D CD  1 
ATOM   275  O OE1 . GLN A 1 33  ? -26.113 -23.675 30.818  1   37.24  ? 203 GLN D OE1 1 
ATOM   276  N NE2 . GLN A 1 33  ? -27.424 -22.002 30.102  1   33.24  ? 203 GLN D NE2 1 
ATOM   277  N N   . PRO A 1 34  ? -24.328 -27.285 29.19   1   40.63  ? 204 PRO D N   1 
ATOM   278  C CA  . PRO A 1 34  ? -23.62  -28.529 29.519  1   41.91  ? 204 PRO D CA  1 
ATOM   279  C C   . PRO A 1 34  ? -23.943 -29.124 30.889  1   42.35  ? 204 PRO D C   1 
ATOM   280  O O   . PRO A 1 34  ? -24.076 -30.338 31      1   47.26  ? 204 PRO D O   1 
ATOM   281  C CB  . PRO A 1 34  ? -22.137 -28.218 29.342  1   40.36  ? 204 PRO D CB  1 
ATOM   282  C CG  . PRO A 1 34  ? -22.08  -26.699 29.432  1   39.61  ? 204 PRO D CG  1 
ATOM   283  C CD  . PRO A 1 34  ? -23.412 -26.159 28.948  1   39.02  ? 204 PRO D CD  1 
ATOM   284  N N   . ASP A 1 35  ? -24.143 -28.268 31.897  1   41.48  ? 205 ASP D N   1 
ATOM   285  C CA  . ASP A 1 35  ? -24.12  -28.689 33.287  1   42.37  ? 205 ASP D CA  1 
ATOM   286  C C   . ASP A 1 35  ? -25.507 -28.7   33.933  1   39.02  ? 205 ASP D C   1 
ATOM   287  O O   . ASP A 1 35  ? -25.73  -29.471 34.854  1   41.71  ? 205 ASP D O   1 
ATOM   288  C CB  . ASP A 1 35  ? -23.091 -27.915 34.091  1   45.91  ? 205 ASP D CB  1 
ATOM   289  C CG  . ASP A 1 35  ? -22.889 -28.397 35.522  1   50.62  ? 205 ASP D CG  1 
ATOM   290  O OD1 . ASP A 1 35  ? -22.889 -29.647 35.744  1   56.4   ? 205 ASP D OD1 1 
ATOM   291  O OD2 . ASP A 1 35  ? -22.706 -27.522 36.4    1   48.78  ? 205 ASP D OD2 1 
ATOM   292  N N   . ILE A 1 36  ? -26.431 -27.854 33.483  1   35.83  ? 206 ILE D N   1 
ATOM   293  C CA  . ILE A 1 36  ? -27.757 -27.83  34.079  1   36.03  ? 206 ILE D CA  1 
ATOM   294  C C   . ILE A 1 36  ? -28.759 -28.536 33.167  1   39.21  ? 206 ILE D C   1 
ATOM   295  O O   . ILE A 1 36  ? -28.509 -28.707 31.966  1   43.23  ? 206 ILE D O   1 
ATOM   296  C CB  . ILE A 1 36  ? -28.221 -26.397 34.397  1   35.23  ? 206 ILE D CB  1 
ATOM   297  C CG1 . ILE A 1 36  ? -28.269 -25.513 33.152  1   35.07  ? 206 ILE D CG1 1 
ATOM   298  C CG2 . ILE A 1 36  ? -27.407 -25.775 35.537  1   34.04  ? 206 ILE D CG2 1 
ATOM   299  C CD1 . ILE A 1 36  ? -29.124 -24.261 33.305  1   36.47  ? 206 ILE D CD1 1 
ATOM   300  N N   . THR A 1 37  ? -29.906 -28.937 33.755  1   38.5   ? 207 THR D N   1 
ATOM   301  C CA  . THR A 1 37  ? -30.924 -29.754 33.091  1   38.55  ? 207 THR D CA  1 
ATOM   302  C C   . THR A 1 37  ? -32.316 -29.191 33.368  1   38.62  ? 207 THR D C   1 
ATOM   303  O O   . THR A 1 37  ? -32.48  -28.371 34.271  1   37.25  ? 207 THR D O   1 
ATOM   304  C CB  . THR A 1 37  ? -30.852 -31.214 33.537  1   37.51  ? 207 THR D CB  1 
ATOM   305  O OG1 . THR A 1 37  ? -31.267 -31.312 34.898  1   37.83  ? 207 THR D OG1 1 
ATOM   306  C CG2 . THR A 1 37  ? -29.466 -31.796 33.356  1   37.13  ? 207 THR D CG2 1 
ATOM   307  N N   . ASN A 1 38  ? -33.315 -29.682 32.609  1   39.29  ? 208 ASN D N   1 
ATOM   308  C CA  . ASN A 1 38  ? -34.707 -29.284 32.794  1   39.15  ? 208 ASN D CA  1 
ATOM   309  C C   . ASN A 1 38  ? -35.174 -29.584 34.216  1   36.44  ? 208 ASN D C   1 
ATOM   310  O O   . ASN A 1 38  ? -35.93  -28.806 34.797  1   33.23  ? 208 ASN D O   1 
ATOM   311  C CB  . ASN A 1 38  ? -35.644 -29.937 31.776  1   42.93  ? 208 ASN D CB  1 
ATOM   312  C CG  . ASN A 1 38  ? -35.651 -29.256 30.425  1   44.57  ? 208 ASN D CG  1 
ATOM   313  O OD1 . ASN A 1 38  ? -35.254 -28.097 30.28   1   45.98  ? 208 ASN D OD1 1 
ATOM   314  N ND2 . ASN A 1 38  ? -36.142 -29.944 29.412  1   47.99  ? 208 ASN D ND2 1 
ATOM   315  N N   . SER A 1 39  ? -34.744 -30.735 34.745  1   36.24  ? 209 SER D N   1 
ATOM   316  C CA  . SER A 1 39  ? -35.146 -31.122 36.079  1   37.41  ? 209 SER D CA  1 
ATOM   317  C C   . SER A 1 39  ? -34.656 -30.099 37.104  1   37.66  ? 209 SER D C   1 
ATOM   318  O O   . SER A 1 39  ? -35.374 -29.773 38.054  1   38.02  ? 209 SER D O   1 
ATOM   319  C CB  . SER A 1 39  ? -34.627 -32.459 36.409  1   38.7   ? 209 SER D CB  1 
ATOM   320  O OG  . SER A 1 39  ? -34.908 -32.68  37.782  1   39.76  ? 209 SER D OG  1 
ATOM   321  N N   . MET A 1 40  ? -33.408 -29.646 36.927  1   36.83  ? 210 MET D N   1 
ATOM   322  C CA  . MET A 1 40  ? -32.812 -28.615 37.766  1   36.83  ? 210 MET D CA  1 
ATOM   323  C C   . MET A 1 40  ? -33.62  -27.303 37.726  1   35.54  ? 210 MET D C   1 
ATOM   324  O O   . MET A 1 40  ? -33.941 -26.729 38.766  1   34.03  ? 210 MET D O   1 
ATOM   325  C CB  . MET A 1 40  ? -31.363 -28.359 37.339  1   35.85  ? 210 MET D CB  1 
ATOM   326  C CG  . MET A 1 40  ? -30.458 -29.534 37.587  1   37.95  ? 210 MET D CG  1 
ATOM   327  S SD  . MET A 1 40  ? -28.72  -29.076 37.427  1   38.29  ? 210 MET D SD  1 
ATOM   328  C CE  . MET A 1 40  ? -27.948 -30.651 37.012  1   37.38  ? 210 MET D CE  1 
ATOM   329  N N   . ARG A 1 41  ? -33.965 -26.842 36.515  1   33.66  ? 211 ARG D N   1 
ATOM   330  C CA  . ARG A 1 41  ? -34.825 -25.687 36.315  1   31.65  ? 211 ARG D CA  1 
ATOM   331  C C   . ARG A 1 41  ? -36.182 -25.858 37.011  1   32.04  ? 211 ARG D C   1 
ATOM   332  O O   . ARG A 1 41  ? -36.782 -24.888 37.455  1   33.16  ? 211 ARG D O   1 
ATOM   333  C CB  . ARG A 1 41  ? -34.964 -25.458 34.805  1   30.06  ? 211 ARG D CB  1 
ATOM   334  C CG  . ARG A 1 41  ? -35.823 -24.256 34.463  1   29.19  ? 211 ARG D CG  1 
ATOM   335  C CD  . ARG A 1 41  ? -36.171 -24.23  32.981  1   30.87  ? 211 ARG D CD  1 
ATOM   336  N NE  . ARG A 1 41  ? -37.21  -23.245 32.652  1   29.84  ? 211 ARG D NE  1 
ATOM   337  C CZ  . ARG A 1 41  ? -38.461 -23.273 33.1    1   28.76  ? 211 ARG D CZ  1 
ATOM   338  N NH1 . ARG A 1 41  ? -38.92  -24.312 33.758  1   28.76  ? 211 ARG D NH1 1 
ATOM   339  N NH2 . ARG A 1 41  ? -39.248 -22.244 32.888  1   28.27  ? 211 ARG D NH2 1 
ATOM   340  N N   . ALA A 1 42  ? -36.707 -27.079 37.08   1   33.05  ? 212 ALA D N   1 
ATOM   341  C CA  . ALA A 1 42  ? -37.969 -27.3   37.766  1   33.83  ? 212 ALA D CA  1 
ATOM   342  C C   . ALA A 1 42  ? -37.816 -27.037 39.266  1   35.02  ? 212 ALA D C   1 
ATOM   343  O O   . ALA A 1 42  ? -38.689 -26.398 39.851  1   36.24  ? 212 ALA D O   1 
ATOM   344  C CB  . ALA A 1 42  ? -38.494 -28.692 37.486  1   34.92  ? 212 ALA D CB  1 
ATOM   345  N N   . ILE A 1 43  ? -36.715 -27.511 39.882  1   33.91  ? 213 ILE D N   1 
ATOM   346  C CA  . ILE A 1 43  ? -36.411 -27.204 41.276  1   33.23  ? 213 ILE D CA  1 
ATOM   347  C C   . ILE A 1 43  ? -36.335 -25.693 41.524  1   31.33  ? 213 ILE D C   1 
ATOM   348  O O   . ILE A 1 43  ? -36.824 -25.198 42.53   1   31.38  ? 213 ILE D O   1 
ATOM   349  C CB  . ILE A 1 43  ? -35.093 -27.852 41.715  1   33.26  ? 213 ILE D CB  1 
ATOM   350  C CG1 . ILE A 1 43  ? -35.139 -29.379 41.63   1   34.35  ? 213 ILE D CG1 1 
ATOM   351  C CG2 . ILE A 1 43  ? -34.654 -27.324 43.089  1   32.8   ? 213 ILE D CG2 1 
ATOM   352  C CD1 . ILE A 1 43  ? -33.789 -30.045 41.868  1   34.44  ? 213 ILE D CD1 1 
ATOM   353  N N   . LEU A 1 44  ? -35.705 -24.962 40.608  1   29.94  ? 214 LEU D N   1 
ATOM   354  C CA  . LEU A 1 44  ? -35.586 -23.521 40.718  1   29.29  ? 214 LEU D CA  1 
ATOM   355  C C   . LEU A 1 44  ? -36.948 -22.845 40.678  1   29.93  ? 214 LEU D C   1 
ATOM   356  O O   . LEU A 1 44  ? -37.252 -22.012 41.526  1   32.61  ? 214 LEU D O   1 
ATOM   357  C CB  . LEU A 1 44  ? -34.71  -22.956 39.607  1   26.95  ? 214 LEU D CB  1 
ATOM   358  C CG  . LEU A 1 44  ? -34.497 -21.442 39.672  1   24.67  ? 214 LEU D CG  1 
ATOM   359  C CD1 . LEU A 1 44  ? -33.757 -21.123 40.961  1   24.79  ? 214 LEU D CD1 1 
ATOM   360  C CD2 . LEU A 1 44  ? -33.731 -20.938 38.45   1   23.47  ? 214 LEU D CD2 1 
ATOM   361  N N   . VAL A 1 45  ? -37.722 -23.139 39.642  1   29.01  ? 215 VAL D N   1 
ATOM   362  C CA  . VAL A 1 45  ? -38.948 -22.399 39.45   1   30.33  ? 215 VAL D CA  1 
ATOM   363  C C   . VAL A 1 45  ? -39.863 -22.67  40.637  1   33.56  ? 215 VAL D C   1 
ATOM   364  O O   . VAL A 1 45  ? -40.49  -21.763 41.173  1   36.94  ? 215 VAL D O   1 
ATOM   365  C CB  . VAL A 1 45  ? -39.618 -22.773 38.119  1   31.28  ? 215 VAL D CB  1 
ATOM   366  C CG1 . VAL A 1 45  ? -41.055 -22.243 38.05   1   30.51  ? 215 VAL D CG1 1 
ATOM   367  C CG2 . VAL A 1 45  ? -38.756 -22.359 36.91   1   28.56  ? 215 VAL D CG2 1 
ATOM   368  N N   . ASP A 1 46  ? -39.914 -23.928 41.065  1   35.36  ? 216 ASP D N   1 
ATOM   369  C CA  . ASP A 1 46  ? -40.698 -24.294 42.227  1   37.09  ? 216 ASP D CA  1 
ATOM   370  C C   . ASP A 1 46  ? -40.24  -23.478 43.435  1   38.68  ? 216 ASP D C   1 
ATOM   371  O O   . ASP A 1 46  ? -41.079 -22.98  44.183  1   42.02  ? 216 ASP D O   1 
ATOM   372  C CB  . ASP A 1 46  ? -40.562 -25.774 42.503  1   38.18  ? 216 ASP D CB  1 
ATOM   373  C CG  . ASP A 1 46  ? -41.541 -26.309 43.531  1   41.21  ? 216 ASP D CG  1 
ATOM   374  O OD1 . ASP A 1 46  ? -42.733 -26.49  43.186  1   42.3   ? 216 ASP D OD1 1 
ATOM   375  O OD2 . ASP A 1 46  ? -41.096 -26.548 44.663  1   42.82  ? 216 ASP D OD2 1 
ATOM   376  N N   . TRP A 1 47  ? -38.917 -23.356 43.627  1   35.9   ? 217 TRP D N   1 
ATOM   377  C CA  . TRP A 1 47  ? -38.387 -22.537 44.699  1   36.6   ? 217 TRP D CA  1 
ATOM   378  C C   . TRP A 1 47  ? -38.835 -21.078 44.561  1   38.1   ? 217 TRP D C   1 
ATOM   379  O O   . TRP A 1 47  ? -39.08  -20.395 45.557  1   38.31  ? 217 TRP D O   1 
ATOM   380  C CB  . TRP A 1 47  ? -36.857 -22.613 44.734  1   36.4   ? 217 TRP D CB  1 
ATOM   381  C CG  . TRP A 1 47  ? -36.24  -21.751 45.814  1   35.17  ? 217 TRP D CG  1 
ATOM   382  C CD1 . TRP A 1 47  ? -36.367 -21.95  47.154  1   36.04  ? 217 TRP D CD1 1 
ATOM   383  C CD2 . TRP A 1 47  ? -35.404 -20.584 45.656  1   32.14  ? 217 TRP D CD2 1 
ATOM   384  N NE1 . TRP A 1 47  ? -35.669 -20.998 47.835  1   36.05  ? 217 TRP D NE1 1 
ATOM   385  C CE2 . TRP A 1 47  ? -35.072 -20.14  46.951  1   33.56  ? 217 TRP D CE2 1 
ATOM   386  C CE3 . TRP A 1 47  ? -34.906 -19.88  44.561  1   30.05  ? 217 TRP D CE3 1 
ATOM   387  C CZ2 . TRP A 1 47  ? -34.278 -19.019 47.194  1   32.32  ? 217 TRP D CZ2 1 
ATOM   388  C CZ3 . TRP A 1 47  ? -34.115 -18.778 44.792  1   29.56  ? 217 TRP D CZ3 1 
ATOM   389  C CH2 . TRP A 1 47  ? -33.804 -18.357 46.09   1   31.03  ? 217 TRP D CH2 1 
ATOM   390  N N   . LEU A 1 48  ? -38.918 -20.577 43.327  1   37.33  ? 218 LEU D N   1 
ATOM   391  C CA  . LEU A 1 48  ? -39.35  -19.207 43.15   1   38.07  ? 218 LEU D CA  1 
ATOM   392  C C   . LEU A 1 48  ? -40.79  -19.037 43.625  1   40.6   ? 218 LEU D C   1 
ATOM   393  O O   . LEU A 1 48  ? -41.099 -18.032 44.271  1   42.7   ? 218 LEU D O   1 
ATOM   394  C CB  . LEU A 1 48  ? -39.101 -18.789 41.707  1   36.57  ? 218 LEU D CB  1 
ATOM   395  C CG  . LEU A 1 48  ? -37.615 -18.604 41.366  1   36.02  ? 218 LEU D CG  1 
ATOM   396  C CD1 . LEU A 1 48  ? -37.413 -18.468 39.878  1   36.4   ? 218 LEU D CD1 1 
ATOM   397  C CD2 . LEU A 1 48  ? -37.003 -17.402 42.069  1   33.17  ? 218 LEU D CD2 1 
ATOM   398  N N   . VAL A 1 49  ? -41.64  -20.039 43.345  1   40.7   ? 219 VAL D N   1 
ATOM   399  C CA  . VAL A 1 49  ? -43.025 -20.058 43.811  1   41.71  ? 219 VAL D CA  1 
ATOM   400  C C   . VAL A 1 49  ? -43.076 -19.863 45.328  1   42.17  ? 219 VAL D C   1 
ATOM   401  O O   . VAL A 1 49  ? -43.765 -18.967 45.82   1   42.39  ? 219 VAL D O   1 
ATOM   402  C CB  . VAL A 1 49  ? -43.771 -21.338 43.379  1   40.96  ? 219 VAL D CB  1 
ATOM   403  C CG1 . VAL A 1 49  ? -45.141 -21.468 44.029  1   40.07  ? 219 VAL D CG1 1 
ATOM   404  C CG2 . VAL A 1 49  ? -43.905 -21.405 41.863  1   39.29  ? 219 VAL D CG2 1 
ATOM   405  N N   . GLU A 1 50  ? -42.342 -20.706 46.056  1   41.93  ? 220 GLU D N   1 
ATOM   406  C CA  . GLU A 1 50  ? -42.296 -20.606 47.503  1   43.8   ? 220 GLU D CA  1 
ATOM   407  C C   . GLU A 1 50  ? -41.88  -19.209 47.928  1   44.15  ? 220 GLU D C   1 
ATOM   408  O O   . GLU A 1 50  ? -42.398 -18.708 48.923  1   47.2   ? 220 GLU D O   1 
ATOM   409  C CB  . GLU A 1 50  ? -41.212 -21.452 48.155  1   44.51  ? 220 GLU D CB  1 
ATOM   410  C CG  . GLU A 1 50  ? -41.423 -22.936 47.908  1   50.68  ? 220 GLU D CG  1 
ATOM   411  C CD  . GLU A 1 50  ? -40.74  -23.717 49.002  1   55.05  ? 220 GLU D CD  1 
ATOM   412  O OE1 . GLU A 1 50  ? -41.468 -24.469 49.693  1   58.83  ? 220 GLU D OE1 1 
ATOM   413  O OE2 . GLU A 1 50  ? -39.511 -23.536 49.169  1   54.74  ? 220 GLU D OE2 1 
ATOM   414  N N   . VAL A 1 51  ? -40.903 -18.633 47.213  1   40.66  ? 221 VAL D N   1 
ATOM   415  C CA  . VAL A 1 51  ? -40.33  -17.358 47.602  1   38.19  ? 221 VAL D CA  1 
ATOM   416  C C   . VAL A 1 51  ? -41.394 -16.276 47.437  1   39.88  ? 221 VAL D C   1 
ATOM   417  O O   . VAL A 1 51  ? -41.562 -15.462 48.35   1   42.2   ? 221 VAL D O   1 
ATOM   418  C CB  . VAL A 1 51  ? -39.024 -17.045 46.857  1   33.86  ? 221 VAL D CB  1 
ATOM   419  C CG1 . VAL A 1 51  ? -38.637 -15.585 46.988  1   32.16  ? 221 VAL D CG1 1 
ATOM   420  C CG2 . VAL A 1 51  ? -37.895 -17.927 47.349  1   32.91  ? 221 VAL D CG2 1 
ATOM   421  N N   . GLY A 1 52  ? -42.121 -16.306 46.304  1   38.12  ? 222 GLY D N   1 
ATOM   422  C CA  . GLY A 1 52  ? -43.211 -15.377 46.061  1   38.37  ? 222 GLY D CA  1 
ATOM   423  C C   . GLY A 1 52  ? -44.278 -15.467 47.15   1   43.92  ? 222 GLY D C   1 
ATOM   424  O O   . GLY A 1 52  ? -44.903 -14.468 47.483  1   44.16  ? 222 GLY D O   1 
ATOM   425  N N   . GLU A 1 53  ? -44.477 -16.678 47.697  1   49.07  ? 223 GLU D N   1 
ATOM   426  C CA  . GLU A 1 53  ? -45.543 -16.985 48.642  1   52.62  ? 223 GLU D CA  1 
ATOM   427  C C   . GLU A 1 53  ? -45.166 -16.467 50.031  1   53.38  ? 223 GLU D C   1 
ATOM   428  O O   . GLU A 1 53  ? -45.991 -15.874 50.717  1   56.09  ? 223 GLU D O   1 
ATOM   429  C CB  . GLU A 1 53  ? -45.753 -18.5   48.613  1   59.18  ? 223 GLU D CB  1 
ATOM   430  C CG  . GLU A 1 53  ? -46.965 -19.003 49.389  1   74.47  ? 223 GLU D CG  1 
ATOM   431  C CD  . GLU A 1 53  ? -48.275 -18.999 48.613  1   87.18  ? 223 GLU D CD  1 
ATOM   432  O OE1 . GLU A 1 53  ? -48.471 -18.081 47.762  1   82.54  ? 223 GLU D OE1 1 
ATOM   433  O OE2 . GLU A 1 53  ? -49.11  -19.904 48.909  1   88.91  ? 223 GLU D OE2 1 
ATOM   434  N N   . GLU A 1 54  ? -43.91  -16.71  50.431  1   52.37  ? 224 GLU D N   1 
ATOM   435  C CA  . GLU A 1 54  ? -43.318 -16.26  51.679  1   52.71  ? 224 GLU D CA  1 
ATOM   436  C C   . GLU A 1 54  ? -43.422 -14.744 51.782  1   51.46  ? 224 GLU D C   1 
ATOM   437  O O   . GLU A 1 54  ? -43.885 -14.251 52.8    1   53.41  ? 224 GLU D O   1 
ATOM   438  C CB  . GLU A 1 54  ? -41.848 -16.691 51.675  1   56.74  ? 224 GLU D CB  1 
ATOM   439  C CG  . GLU A 1 54  ? -41.014 -16.275 52.883  1   62.76  ? 224 GLU D CG  1 
ATOM   440  C CD  . GLU A 1 54  ? -41.242 -17.118 54.111  1   72.11  ? 224 GLU D CD  1 
ATOM   441  O OE1 . GLU A 1 54  ? -41.92  -18.164 54.009  1   76.12  ? 224 GLU D OE1 1 
ATOM   442  O OE2 . GLU A 1 54  ? -40.713 -16.73  55.177  1   77.08  ? 224 GLU D OE2 1 
ATOM   443  N N   . TYR A 1 55  ? -42.988 -14.03  50.729  1   49.24  ? 225 TYR D N   1 
ATOM   444  C CA  . TYR A 1 55  ? -42.909 -12.578 50.707  1   50.06  ? 225 TYR D CA  1 
ATOM   445  C C   . TYR A 1 55  ? -44.192 -11.938 50.168  1   54.74  ? 225 TYR D C   1 
ATOM   446  O O   . TYR A 1 55  ? -44.259 -10.709 50.037  1   57.89  ? 225 TYR D O   1 
ATOM   447  C CB  . TYR A 1 55  ? -41.657 -12.152 49.935  1   48.79  ? 225 TYR D CB  1 
ATOM   448  C CG  . TYR A 1 55  ? -40.397 -12.378 50.755  1   53.16  ? 225 TYR D CG  1 
ATOM   449  C CD1 . TYR A 1 55  ? -40.185 -11.663 51.93   1   56.21  ? 225 TYR D CD1 1 
ATOM   450  C CD2 . TYR A 1 55  ? -39.439 -13.315 50.386  1   51.67  ? 225 TYR D CD2 1 
ATOM   451  C CE1 . TYR A 1 55  ? -39.065 -11.876 52.718  1   55.6   ? 225 TYR D CE1 1 
ATOM   452  C CE2 . TYR A 1 55  ? -38.318 -13.536 51.175  1   50.68  ? 225 TYR D CE2 1 
ATOM   453  C CZ  . TYR A 1 55  ? -38.128 -12.82  52.345  1   51.6   ? 225 TYR D CZ  1 
ATOM   454  O OH  . TYR A 1 55  ? -37.039 -12.989 53.155  1   50.75  ? 225 TYR D OH  1 
ATOM   455  N N   . LYS A 1 56  ? -45.196 -12.772 49.842  1   55.31  ? 226 LYS D N   1 
ATOM   456  C CA  . LYS A 1 56  ? -46.475 -12.317 49.307  1   52.96  ? 226 LYS D CA  1 
ATOM   457  C C   . LYS A 1 56  ? -46.252 -11.369 48.121  1   48.35  ? 226 LYS D C   1 
ATOM   458  O O   . LYS A 1 56  ? -46.739 -10.252 48.123  1   48.89  ? 226 LYS D O   1 
ATOM   459  C CB  . LYS A 1 56  ? -47.342 -11.784 50.457  1   56.19  ? 226 LYS D CB  1 
ATOM   460  C CG  . LYS A 1 56  ? -48.281 -12.811 51.096  1   62.37  ? 226 LYS D CG  1 
ATOM   461  C CD  . LYS A 1 56  ? -48.465 -12.708 52.608  1   67.18  ? 226 LYS D CD  1 
ATOM   462  C CE  . LYS A 1 56  ? -47.463 -13.579 53.343  1   70.54  ? 226 LYS D CE  1 
ATOM   463  N NZ  . LYS A 1 56  ? -47.185 -13.147 54.715  1   74.26  ? 226 LYS D NZ  1 
ATOM   464  N N   . LEU A 1 57  ? -45.506 -11.822 47.108  1   44.28  ? 227 LEU D N   1 
ATOM   465  C CA  . LEU A 1 57  ? -45.324 -11.105 45.856  1   40.57  ? 227 LEU D CA  1 
ATOM   466  C C   . LEU A 1 57  ? -46.469 -11.426 44.9    1   40.47  ? 227 LEU D C   1 
ATOM   467  O O   . LEU A 1 57  ? -47.098 -12.482 44.995  1   41.19  ? 227 LEU D O   1 
ATOM   468  C CB  . LEU A 1 57  ? -44.008 -11.529 45.205  1   38.1   ? 227 LEU D CB  1 
ATOM   469  C CG  . LEU A 1 57  ? -42.762 -11.539 46.095  1   37.73  ? 227 LEU D CG  1 
ATOM   470  C CD1 . LEU A 1 57  ? -41.591 -12.056 45.302  1   35.52  ? 227 LEU D CD1 1 
ATOM   471  C CD2 . LEU A 1 57  ? -42.448 -10.159 46.672  1   37.3   ? 227 LEU D CD2 1 
ATOM   472  N N   . GLN A 1 58  ? -46.683 -10.522 43.936  1   39.97  ? 228 GLN D N   1 
ATOM   473  C CA  . GLN A 1 58  ? -47.68  -10.719 42.896  1   41.64  ? 228 GLN D CA  1 
ATOM   474  C C   . GLN A 1 58  ? -47.32  -11.933 42.057  1   41.34  ? 228 GLN D C   1 
ATOM   475  O O   . GLN A 1 58  ? -46.154 -12.307 42.008  1   38.47  ? 228 GLN D O   1 
ATOM   476  C CB  . GLN A 1 58  ? -47.712 -9.547  41.922  1   40.2   ? 228 GLN D CB  1 
ATOM   477  C CG  . GLN A 1 58  ? -48.088 -8.232  42.572  1   41.87  ? 228 GLN D CG  1 
ATOM   478  C CD  . GLN A 1 58  ? -49.522 -8.24   43.04   1   43.41  ? 228 GLN D CD  1 
ATOM   479  O OE1 . GLN A 1 58  ? -50.453 -8.257  42.233  1   45.38  ? 228 GLN D OE1 1 
ATOM   480  N NE2 . GLN A 1 58  ? -49.705 -8.186  44.35   1   43.95  ? 228 GLN D NE2 1 
ATOM   481  N N   . ASN A 1 59  ? -48.333 -12.496 41.38   1   43.8   ? 229 ASN D N   1 
ATOM   482  C CA  . ASN A 1 59  ? -48.111 -13.627 40.496  1   44.21  ? 229 ASN D CA  1 
ATOM   483  C C   . ASN A 1 59  ? -47.414 -13.142 39.229  1   41.77  ? 229 ASN D C   1 
ATOM   484  O O   . ASN A 1 59  ? -46.669 -13.889 38.594  1   38.19  ? 229 ASN D O   1 
ATOM   485  C CB  . ASN A 1 59  ? -49.379 -14.445 40.277  1   47.57  ? 229 ASN D CB  1 
ATOM   486  C CG  . ASN A 1 59  ? -49.667 -15.339 41.463  1   49.93  ? 229 ASN D CG  1 
ATOM   487  O OD1 . ASN A 1 59  ? -48.893 -16.247 41.789  1   51.47  ? 229 ASN D OD1 1 
ATOM   488  N ND2 . ASN A 1 59  ? -50.775 -15.089 42.136  1   50.91  ? 229 ASN D ND2 1 
ATOM   489  N N   . GLU A 1 60  ? -47.658 -11.873 38.884  1   41.18  ? 230 GLU D N   1 
ATOM   490  C CA  . GLU A 1 60  ? -46.994 -11.294 37.733  1   40.06  ? 230 GLU D CA  1 
ATOM   491  C C   . GLU A 1 60  ? -45.479 -11.382 37.915  1   40.87  ? 230 GLU D C   1 
ATOM   492  O O   . GLU A 1 60  ? -44.764 -11.758 36.989  1   43.11  ? 230 GLU D O   1 
ATOM   493  C CB  . GLU A 1 60  ? -47.457 -9.863  37.486  1   39.09  ? 230 GLU D CB  1 
ATOM   494  C CG  . GLU A 1 60  ? -46.716 -9.222  36.317  1   37.61  ? 230 GLU D CG  1 
ATOM   495  C CD  . GLU A 1 60  ? -46.973 -9.847  34.962  1   36.71  ? 230 GLU D CD  1 
ATOM   496  O OE1 . GLU A 1 60  ? -47.879 -10.682 34.851  1   36.68  ? 230 GLU D OE1 1 
ATOM   497  O OE2 . GLU A 1 60  ? -46.259 -9.479  34.019  1   37.7   ? 230 GLU D OE2 1 
ATOM   498  N N   . THR A 1 61  ? -45.006 -11.04  39.122  1   38.93  ? 231 THR D N   1 
ATOM   499  C CA  . THR A 1 61  ? -43.59  -11.026 39.462  1   36.97  ? 231 THR D CA  1 
ATOM   500  C C   . THR A 1 61  ? -42.966 -12.396 39.197  1   38.04  ? 231 THR D C   1 
ATOM   501  O O   . THR A 1 61  ? -41.834 -12.476 38.718  1   38.32  ? 231 THR D O   1 
ATOM   502  C CB  . THR A 1 61  ? -43.397 -10.646 40.932  1   36.41  ? 231 THR D CB  1 
ATOM   503  O OG1 . THR A 1 61  ? -43.98  -9.367  41.143  1   37.07  ? 231 THR D OG1 1 
ATOM   504  C CG2 . THR A 1 61  ? -41.934 -10.588 41.345  1   35.9   ? 231 THR D CG2 1 
ATOM   505  N N   . LEU A 1 62  ? -43.698 -13.46  39.555  1   37.45  ? 232 LEU D N   1 
ATOM   506  C CA  . LEU A 1 62  ? -43.19  -14.813 39.436  1   36.37  ? 232 LEU D CA  1 
ATOM   507  C C   . LEU A 1 62  ? -42.97  -15.136 37.963  1   36.29  ? 232 LEU D C   1 
ATOM   508  O O   . LEU A 1 62  ? -41.931 -15.688 37.603  1   37.43  ? 232 LEU D O   1 
ATOM   509  C CB  . LEU A 1 62  ? -44.151 -15.802 40.086  1   36.54  ? 232 LEU D CB  1 
ATOM   510  C CG  . LEU A 1 62  ? -43.867 -17.283 39.819  1   36.68  ? 232 LEU D CG  1 
ATOM   511  C CD1 . LEU A 1 62  ? -42.487 -17.678 40.313  1   36.3   ? 232 LEU D CD1 1 
ATOM   512  C CD2 . LEU A 1 62  ? -44.929 -18.156 40.449  1   37.04  ? 232 LEU D CD2 1 
ATOM   513  N N   . HIS A 1 63  ? -43.959 -14.795 37.129  1   35.57  ? 233 HIS D N   1 
ATOM   514  C CA  . HIS A 1 63  ? -43.856 -15.086 35.715  1   36.6   ? 233 HIS D CA  1 
ATOM   515  C C   . HIS A 1 63  ? -42.733 -14.289 35.07   1   37.27  ? 233 HIS D C   1 
ATOM   516  O O   . HIS A 1 63  ? -42.122 -14.803 34.135  1   38.84  ? 233 HIS D O   1 
ATOM   517  C CB  . HIS A 1 63  ? -45.151 -14.777 34.971  1   38.69  ? 233 HIS D CB  1 
ATOM   518  C CG  . HIS A 1 63  ? -46.225 -15.761 35.215  1   40.26  ? 233 HIS D CG  1 
ATOM   519  N ND1 . HIS A 1 63  ? -46.716 -15.996 36.48   1   42     ? 233 HIS D ND1 1 
ATOM   520  C CD2 . HIS A 1 63  ? -46.866 -16.579 34.409  1   40.5   ? 233 HIS D CD2 1 
ATOM   521  C CE1 . HIS A 1 63  ? -47.675 -16.907 36.422  1   41.69  ? 233 HIS D CE1 1 
ATOM   522  N NE2 . HIS A 1 63  ? -47.772 -17.274 35.175  1   42.8   ? 233 HIS D NE2 1 
ATOM   523  N N   . LEU A 1 64  ? -42.493 -13.049 35.535  1   35.09  ? 234 LEU D N   1 
ATOM   524  C CA  . LEU A 1 64  ? -41.445 -12.212 34.961  1   33.1   ? 234 LEU D CA  1 
ATOM   525  C C   . LEU A 1 64  ? -40.084 -12.856 35.222  1   33.1   ? 234 LEU D C   1 
ATOM   526  O O   . LEU A 1 64  ? -39.302 -13.08  34.276  1   34.19  ? 234 LEU D O   1 
ATOM   527  C CB  . LEU A 1 64  ? -41.515 -10.784 35.499  1   31.37  ? 234 LEU D CB  1 
ATOM   528  C CG  . LEU A 1 64  ? -42.645 -9.9    34.959  1   30.69  ? 234 LEU D CG  1 
ATOM   529  C CD1 . LEU A 1 64  ? -42.712 -8.597  35.719  1   30.51  ? 234 LEU D CD1 1 
ATOM   530  C CD2 . LEU A 1 64  ? -42.493 -9.616  33.48   1   28.6   ? 234 LEU D CD2 1 
ATOM   531  N N   . ALA A 1 65  ? -39.846 -13.173 36.507  1   30.86  ? 235 ALA D N   1 
ATOM   532  C CA  . ALA A 1 65  ? -38.634 -13.859 36.93   1   30.46  ? 235 ALA D CA  1 
ATOM   533  C C   . ALA A 1 65  ? -38.326 -15.03  35.991  1   30.21  ? 235 ALA D C   1 
ATOM   534  O O   . ALA A 1 65  ? -37.195 -15.171 35.522  1   29.63  ? 235 ALA D O   1 
ATOM   535  C CB  . ALA A 1 65  ? -38.73  -14.293 38.372  1   29.61  ? 235 ALA D CB  1 
ATOM   536  N N   . VAL A 1 66  ? -39.332 -15.861 35.703  1   29.29  ? 236 VAL D N   1 
ATOM   537  C CA  . VAL A 1 66  ? -39.093 -17.074 34.939  1   30.52  ? 236 VAL D CA  1 
ATOM   538  C C   . VAL A 1 66  ? -38.67  -16.73  33.508  1   32.29  ? 236 VAL D C   1 
ATOM   539  O O   . VAL A 1 66  ? -37.747 -17.358 32.969  1   32.59  ? 236 VAL D O   1 
ATOM   540  C CB  . VAL A 1 66  ? -40.299 -18.024 34.994  1   29.36  ? 236 VAL D CB  1 
ATOM   541  C CG1 . VAL A 1 66  ? -40.125 -19.182 34.022  1   27.3   ? 236 VAL D CG1 1 
ATOM   542  C CG2 . VAL A 1 66  ? -40.517 -18.504 36.43   1   29.61  ? 236 VAL D CG2 1 
ATOM   543  N N   . ASN A 1 67  ? -39.344 -15.724 32.915  1   32.02  ? 237 ASN D N   1 
ATOM   544  C CA  . ASN A 1 67  ? -38.972 -15.174 31.62   1   30.33  ? 237 ASN D CA  1 
ATOM   545  C C   . ASN A 1 67  ? -37.531 -14.672 31.682  1   29.54  ? 237 ASN D C   1 
ATOM   546  O O   . ASN A 1 67  ? -36.745 -14.935 30.765  1   28.4   ? 237 ASN D O   1 
ATOM   547  C CB  . ASN A 1 67  ? -39.904 -14.058 31.159  1   31.46  ? 237 ASN D CB  1 
ATOM   548  C CG  . ASN A 1 67  ? -39.443 -13.368 29.884  1   33.13  ? 237 ASN D CG  1 
ATOM   549  O OD1 . ASN A 1 67  ? -38.666 -12.401 29.935  1   32.16  ? 237 ASN D OD1 1 
ATOM   550  N ND2 . ASN A 1 67  ? -39.973 -13.795 28.744  1   33.67  ? 237 ASN D ND2 1 
ATOM   551  N N   . TYR A 1 68  ? -37.198 -13.936 32.757  1   27.16  ? 238 TYR D N   1 
ATOM   552  C CA  . TYR A 1 68  ? -35.863 -13.367 32.85   1   26.53  ? 238 TYR D CA  1 
ATOM   553  C C   . TYR A 1 68  ? -34.827 -14.488 32.812  1   28.31  ? 238 TYR D C   1 
ATOM   554  O O   . TYR A 1 68  ? -33.898 -14.422 32.016  1   28.39  ? 238 TYR D O   1 
ATOM   555  C CB  . TYR A 1 68  ? -35.712 -12.49  34.087  1   25.54  ? 238 TYR D CB  1 
ATOM   556  C CG  . TYR A 1 68  ? -36.601 -11.262 34.088  1   24.64  ? 238 TYR D CG  1 
ATOM   557  C CD1 . TYR A 1 68  ? -37.297 -10.873 32.945  1   24.81  ? 238 TYR D CD1 1 
ATOM   558  C CD2 . TYR A 1 68  ? -36.736 -10.508 35.238  1   23.41  ? 238 TYR D CD2 1 
ATOM   559  C CE1 . TYR A 1 68  ? -38.105 -9.752  32.944  1   24.93  ? 238 TYR D CE1 1 
ATOM   560  C CE2 . TYR A 1 68  ? -37.534 -9.382  35.249  1   24.62  ? 238 TYR D CE2 1 
ATOM   561  C CZ  . TYR A 1 68  ? -38.222 -9.01   34.106  1   25.87  ? 238 TYR D CZ  1 
ATOM   562  O OH  . TYR A 1 68  ? -39.02  -7.905  34.134  1   27.62  ? 238 TYR D OH  1 
ATOM   563  N N   . ILE A 1 69  ? -35.042 -15.53  33.644  1   30.48  ? 239 ILE D N   1 
ATOM   564  C CA  . ILE A 1 69  ? -34.231 -16.743 33.739  1   28.56  ? 239 ILE D CA  1 
ATOM   565  C C   . ILE A 1 69  ? -34.075 -17.437 32.376  1   28.94  ? 239 ILE D C   1 
ATOM   566  O O   . ILE A 1 69  ? -32.959 -17.754 31.963  1   28.14  ? 239 ILE D O   1 
ATOM   567  C CB  . ILE A 1 69  ? -34.799 -17.701 34.805  1   26.59  ? 239 ILE D CB  1 
ATOM   568  C CG1 . ILE A 1 69  ? -34.688 -17.106 36.214  1   25.02  ? 239 ILE D CG1 1 
ATOM   569  C CG2 . ILE A 1 69  ? -34.124 -19.078 34.708  1   25.69  ? 239 ILE D CG2 1 
ATOM   570  C CD1 . ILE A 1 69  ? -35.683 -17.673 37.209  1   24.14  ? 239 ILE D CD1 1 
ATOM   571  N N   . ASP A 1 70  ? -35.186 -17.721 31.68   1   28.98  ? 240 ASP D N   1 
ATOM   572  C CA  . ASP A 1 70  ? -35.056 -18.562 30.498  1   30.17  ? 240 ASP D CA  1 
ATOM   573  C C   . ASP A 1 70  ? -34.316 -17.82  29.402  1   32.26  ? 240 ASP D C   1 
ATOM   574  O O   . ASP A 1 70  ? -33.629 -18.456 28.608  1   34.85  ? 240 ASP D O   1 
ATOM   575  C CB  . ASP A 1 70  ? -36.351 -19.19  30.029  1   29.06  ? 240 ASP D CB  1 
ATOM   576  C CG  . ASP A 1 70  ? -36.934 -20.206 30.999  1   29.89  ? 240 ASP D CG  1 
ATOM   577  O OD1 . ASP A 1 70  ? -36.165 -21.031 31.558  1   29.4   ? 240 ASP D OD1 1 
ATOM   578  O OD2 . ASP A 1 70  ? -38.162 -20.162 31.205  1   30.08  ? 240 ASP D OD2 1 
ATOM   579  N N   . ARG A 1 71  ? -34.433 -16.485 29.389  1   31.79  ? 241 ARG D N   1 
ATOM   580  C CA  . ARG A 1 71  ? -33.784 -15.701 28.346  1   32.28  ? 241 ARG D CA  1 
ATOM   581  C C   . ARG A 1 71  ? -32.289 -15.627 28.619  1   30.29  ? 241 ARG D C   1 
ATOM   582  O O   . ARG A 1 71  ? -31.478 -15.705 27.698  1   32.02  ? 241 ARG D O   1 
ATOM   583  C CB  . ARG A 1 71  ? -34.395 -14.302 28.227  1   33.29  ? 241 ARG D CB  1 
ATOM   584  C CG  . ARG A 1 71  ? -35.743 -14.343 27.518  1   34.07  ? 241 ARG D CG  1 
ATOM   585  C CD  . ARG A 1 71  ? -36.619 -13.167 27.861  1   32.8   ? 241 ARG D CD  1 
ATOM   586  N NE  . ARG A 1 71  ? -35.992 -11.939 27.371  1   34.14  ? 241 ARG D NE  1 
ATOM   587  C CZ  . ARG A 1 71  ? -36.288 -10.728 27.843  1   33.89  ? 241 ARG D CZ  1 
ATOM   588  N NH1 . ARG A 1 71  ? -37.148 -10.615 28.845  1   32.87  ? 241 ARG D NH1 1 
ATOM   589  N NH2 . ARG A 1 71  ? -35.708 -9.656  27.32   1   32.08  ? 241 ARG D NH2 1 
ATOM   590  N N   . PHE A 1 72  ? -31.96  -15.48  29.9    1   27.87  ? 242 PHE D N   1 
ATOM   591  C CA  . PHE A 1 72  ? -30.584 -15.436 30.351  1   26.1   ? 242 PHE D CA  1 
ATOM   592  C C   . PHE A 1 72  ? -29.895 -16.759 30.043  1   27.27  ? 242 PHE D C   1 
ATOM   593  O O   . PHE A 1 72  ? -28.791 -16.741 29.519  1   29.05  ? 242 PHE D O   1 
ATOM   594  C CB  . PHE A 1 72  ? -30.551 -15.179 31.862  1   24.18  ? 242 PHE D CB  1 
ATOM   595  C CG  . PHE A 1 72  ? -29.153 -14.949 32.404  1   24.08  ? 242 PHE D CG  1 
ATOM   596  C CD1 . PHE A 1 72  ? -28.578 -13.68  32.321  1   23.92  ? 242 PHE D CD1 1 
ATOM   597  C CD2 . PHE A 1 72  ? -28.419 -16.007 32.959  1   24.15  ? 242 PHE D CD2 1 
ATOM   598  C CE1 . PHE A 1 72  ? -27.292 -13.485 32.8    1   25.35  ? 242 PHE D CE1 1 
ATOM   599  C CE2 . PHE A 1 72  ? -27.145 -15.806 33.454  1   24.45  ? 242 PHE D CE2 1 
ATOM   600  C CZ  . PHE A 1 72  ? -26.589 -14.547 33.378  1   26.19  ? 242 PHE D CZ  1 
ATOM   601  N N   . LEU A 1 73  ? -30.527 -17.888 30.414  1   26.97  ? 243 LEU D N   1 
ATOM   602  C CA  . LEU A 1 73  ? -29.967 -19.21  30.214  1   26.94  ? 243 LEU D CA  1 
ATOM   603  C C   . LEU A 1 73  ? -29.964 -19.565 28.733  1   28.88  ? 243 LEU D C   1 
ATOM   604  O O   . LEU A 1 73  ? -29.26  -20.492 28.324  1   31.46  ? 243 LEU D O   1 
ATOM   605  C CB  . LEU A 1 73  ? -30.775 -20.23  31.005  1   27.48  ? 243 LEU D CB  1 
ATOM   606  C CG  . LEU A 1 73  ? -30.62  -20.153 32.525  1   28.51  ? 243 LEU D CG  1 
ATOM   607  C CD1 . LEU A 1 73  ? -31.46  -21.22  33.167  1   29.96  ? 243 LEU D CD1 1 
ATOM   608  C CD2 . LEU A 1 73  ? -29.186 -20.326 32.972  1   28.98  ? 243 LEU D CD2 1 
ATOM   609  N N   . SER A 1 74  ? -30.746 -18.825 27.943  1   28.67  ? 244 SER D N   1 
ATOM   610  C CA  . SER A 1 74  ? -30.727 -18.936 26.495  1   32.11  ? 244 SER D CA  1 
ATOM   611  C C   . SER A 1 74  ? -29.405 -18.487 25.868  1   33.79  ? 244 SER D C   1 
ATOM   612  O O   . SER A 1 74  ? -29.178 -18.802 24.696  1   37.12  ? 244 SER D O   1 
ATOM   613  C CB  . SER A 1 74  ? -31.868 -18.172 25.901  1   33.66  ? 244 SER D CB  1 
ATOM   614  O OG  . SER A 1 74  ? -33.067 -18.924 25.974  1   36.26  ? 244 SER D OG  1 
ATOM   615  N N   . SER A 1 75  ? -28.552 -17.762 26.62   1   32.89  ? 245 SER D N   1 
ATOM   616  C CA  . SER A 1 75  ? -27.368 -17.12  26.05   1   35.73  ? 245 SER D CA  1 
ATOM   617  C C   . SER A 1 75  ? -26.139 -17.196 26.956  1   33.28  ? 245 SER D C   1 
ATOM   618  O O   . SER A 1 75  ? -25.042 -16.841 26.54   1   34.6   ? 245 SER D O   1 
ATOM   619  C CB  . SER A 1 75  ? -27.648 -15.69  25.626  1   38.13  ? 245 SER D CB  1 
ATOM   620  O OG  . SER A 1 75  ? -28.423 -15.016 26.612  1   42.6   ? 245 SER D OG  1 
ATOM   621  N N   . MET A 1 76  ? -26.315 -17.643 28.195  1   30.57  ? 246 MET D N   1 
ATOM   622  C CA  . MET A 1 76  ? -25.205 -17.697 29.132  1   30.98  ? 246 MET D CA  1 
ATOM   623  C C   . MET A 1 76  ? -25.166 -19.087 29.75   1   31.88  ? 246 MET D C   1 
ATOM   624  O O   . MET A 1 76  ? -26.099 -19.474 30.461  1   31.83  ? 246 MET D O   1 
ATOM   625  C CB  . MET A 1 76  ? -25.404 -16.68  30.259  1   31.45  ? 246 MET D CB  1 
ATOM   626  C CG  . MET A 1 76  ? -25.526 -15.252 29.775  1   31.84  ? 246 MET D CG  1 
ATOM   627  S SD  . MET A 1 76  ? -23.899 -14.644 29.329  1   37.35  ? 246 MET D SD  1 
ATOM   628  C CE  . MET A 1 76  ? -23.222 -14.274 30.955  1   32.6   ? 246 MET D CE  1 
ATOM   629  N N   . SER A 1 77  ? -24.108 -19.836 29.404  1   32.94  ? 247 SER D N   1 
ATOM   630  C CA  . SER A 1 77  ? -23.691 -21.034 30.124  1   32.79  ? 247 SER D CA  1 
ATOM   631  C C   . SER A 1 77  ? -23.652 -20.733 31.62   1   33.25  ? 247 SER D C   1 
ATOM   632  O O   . SER A 1 77  ? -23.115 -19.705 32.033  1   33.97  ? 247 SER D O   1 
ATOM   633  C CB  . SER A 1 77  ? -22.349 -21.498 29.667  1   32.89  ? 247 SER D CB  1 
ATOM   634  O OG  . SER A 1 77  ? -22.433 -22.241 28.461  1   33.65  ? 247 SER D OG  1 
ATOM   635  N N   . VAL A 1 78  ? -24.281 -21.599 32.421  1   32     ? 248 VAL D N   1 
ATOM   636  C CA  . VAL A 1 78  ? -24.285 -21.405 33.865  1   30.39  ? 248 VAL D CA  1 
ATOM   637  C C   . VAL A 1 78  ? -24.033 -22.744 34.561  1   31.29  ? 248 VAL D C   1 
ATOM   638  O O   . VAL A 1 78  ? -24.794 -23.695 34.365  1   31.13  ? 248 VAL D O   1 
ATOM   639  C CB  . VAL A 1 78  ? -25.613 -20.764 34.314  1   28.33  ? 248 VAL D CB  1 
ATOM   640  C CG1 . VAL A 1 78  ? -25.775 -20.791 35.83   1   26.81  ? 248 VAL D CG1 1 
ATOM   641  C CG2 . VAL A 1 78  ? -25.793 -19.354 33.762  1   26.37  ? 248 VAL D CG2 1 
ATOM   642  N N   . LEU A 1 79  ? -23.011 -22.782 35.42   1   31.48  ? 249 LEU D N   1 
ATOM   643  C CA  . LEU A 1 79  ? -22.756 -24.01  36.215  1   32.48  ? 249 LEU D CA  1 
ATOM   644  C C   . LEU A 1 79  ? -23.884 -24.161 37.246  1   33.25  ? 249 LEU D C   1 
ATOM   645  O O   . LEU A 1 79  ? -24.378 -23.126 37.739  1   33.11  ? 249 LEU D O   1 
ATOM   646  C CB  . LEU A 1 79  ? -21.391 -23.912 36.891  1   31.6   ? 249 LEU D CB  1 
ATOM   647  C CG  . LEU A 1 79  ? -20.177 -24.036 35.967  1   31.2   ? 249 LEU D CG  1 
ATOM   648  C CD1 . LEU A 1 79  ? -18.978 -24.547 36.745  1   31.27  ? 249 LEU D CD1 1 
ATOM   649  C CD2 . LEU A 1 79  ? -20.476 -24.945 34.788  1   31.31  ? 249 LEU D CD2 1 
ATOM   650  N N   . ARG A 1 80  ? -24.263 -25.399 37.568  1   34.85  ? 250 ARG D N   1 
ATOM   651  C CA  . ARG A 1 80  ? -25.383 -25.64  38.516  1   36.36  ? 250 ARG D CA  1 
ATOM   652  C C   . ARG A 1 80  ? -25.195 -24.799 39.79   1   33.73  ? 250 ARG D C   1 
ATOM   653  O O   . ARG A 1 80  ? -26.182 -24.179 40.237  1   31.49  ? 250 ARG D O   1 
ATOM   654  C CB  . ARG A 1 80  ? -25.455 -27.139 38.824  1   41.2   ? 250 ARG D CB  1 
ATOM   655  C CG  . ARG A 1 80  ? -26.382 -27.526 39.967  1   45.26  ? 250 ARG D CG  1 
ATOM   656  C CD  . ARG A 1 80  ? -26.139 -28.96  40.41   1   52.25  ? 250 ARG D CD  1 
ATOM   657  N NE  . ARG A 1 80  ? -24.924 -29.528 39.814  1   58.72  ? 250 ARG D NE  1 
ATOM   658  C CZ  . ARG A 1 80  ? -24.902 -30.583 39.01   1   72.08  ? 250 ARG D CZ  1 
ATOM   659  N NH1 . ARG A 1 80  ? -24.478 -30.456 37.766  1   76.35  ? 250 ARG D NH1 1 
ATOM   660  N NH2 . ARG A 1 80  ? -25.31  -31.759 39.452  1   76.53  ? 250 ARG D NH2 1 
ATOM   661  N N   . GLY A 1 81  ? -23.984 -24.783 40.354  1   33     ? 251 GLY D N   1 
ATOM   662  C CA  . GLY A 1 81  ? -23.739 -24.049 41.611  1   32.79  ? 251 GLY D CA  1 
ATOM   663  C C   . GLY A 1 81  ? -24.142 -22.59  41.511  1   31.81  ? 251 GLY D C   1 
ATOM   664  O O   . GLY A 1 81  ? -24.185 -21.924 42.565  1   32.66  ? 251 GLY D O   1 
ATOM   665  N N   . LYS A 1 82  ? -24.43  -22.101 40.302  1   30.59  ? 252 LYS D N   1 
ATOM   666  C CA  . LYS A 1 82  ? -24.76  -20.701 40.119  1   29.02  ? 252 LYS D CA  1 
ATOM   667  C C   . LYS A 1 82  ? -26.197 -20.549 39.635  1   29.49  ? 252 LYS D C   1 
ATOM   668  O O   . LYS A 1 82  ? -26.639 -19.416 39.444  1   28.78  ? 252 LYS D O   1 
ATOM   669  C CB  . LYS A 1 82  ? -23.748 -20.079 39.153  1   27.56  ? 252 LYS D CB  1 
ATOM   670  C CG  . LYS A 1 82  ? -22.338 -19.971 39.698  1   27.39  ? 252 LYS D CG  1 
ATOM   671  C CD  . LYS A 1 82  ? -22.437 -19.225 41.018  1   27.31  ? 252 LYS D CD  1 
ATOM   672  C CE  . LYS A 1 82  ? -21.199 -18.579 41.495  1   27.76  ? 252 LYS D CE  1 
ATOM   673  N NZ  . LYS A 1 82  ? -20.317 -19.546 42.146  1   29.57  ? 252 LYS D NZ  1 
ATOM   674  N N   . LEU A 1 83  ? -26.911 -21.681 39.453  1   29.86  ? 253 LEU D N   1 
ATOM   675  C CA  . LEU A 1 83  ? -28.288 -21.654 38.979  1   28.86  ? 253 LEU D CA  1 
ATOM   676  C C   . LEU A 1 83  ? -29.145 -20.803 39.92   1   31.37  ? 253 LEU D C   1 
ATOM   677  O O   . LEU A 1 83  ? -29.85  -19.896 39.474  1   33.24  ? 253 LEU D O   1 
ATOM   678  C CB  . LEU A 1 83  ? -28.86  -23.054 38.808  1   27.33  ? 253 LEU D CB  1 
ATOM   679  C CG  . LEU A 1 83  ? -30.229 -23.127 38.123  1   25.94  ? 253 LEU D CG  1 
ATOM   680  C CD1 . LEU A 1 83  ? -30.255 -22.617 36.707  1   24.74  ? 253 LEU D CD1 1 
ATOM   681  C CD2 . LEU A 1 83  ? -30.749 -24.546 38.109  1   27     ? 253 LEU D CD2 1 
ATOM   682  N N   . GLN A 1 84  ? -29.055 -21.051 41.232  1   32.75  ? 254 GLN D N   1 
ATOM   683  C CA  . GLN A 1 84  ? -29.905 -20.325 42.168  1   33.79  ? 254 GLN D CA  1 
ATOM   684  C C   . GLN A 1 84  ? -29.635 -18.816 42.167  1   32.96  ? 254 GLN D C   1 
ATOM   685  O O   . GLN A 1 84  ? -30.527 -18.036 42.451  1   31.84  ? 254 GLN D O   1 
ATOM   686  C CB  . GLN A 1 84  ? -29.719 -20.845 43.587  1   35.29  ? 254 GLN D CB  1 
ATOM   687  C CG  . GLN A 1 84  ? -30.73  -20.27  44.567  1   35.45  ? 254 GLN D CG  1 
ATOM   688  C CD  . GLN A 1 84  ? -30.721 -20.977 45.899  1   38.83  ? 254 GLN D CD  1 
ATOM   689  O OE1 . GLN A 1 84  ? -31.544 -20.692 46.772  1   42.07  ? 254 GLN D OE1 1 
ATOM   690  N NE2 . GLN A 1 84  ? -29.789 -21.902 46.079  1   40.74  ? 254 GLN D NE2 1 
ATOM   691  N N   . LEU A 1 85  ? -28.396 -18.417 41.859  1   33.11  ? 255 LEU D N   1 
ATOM   692  C CA  . LEU A 1 85  ? -27.997 -17.022 41.876  1   32.41  ? 255 LEU D CA  1 
ATOM   693  C C   . LEU A 1 85  ? -28.572 -16.312 40.658  1   31.4   ? 255 LEU D C   1 
ATOM   694  O O   . LEU A 1 85  ? -28.926 -15.148 40.733  1   33.4   ? 255 LEU D O   1 
ATOM   695  C CB  . LEU A 1 85  ? -26.475 -16.923 41.93   1   32.04  ? 255 LEU D CB  1 
ATOM   696  C CG  . LEU A 1 85  ? -25.868 -15.523 41.853  1   31.66  ? 255 LEU D CG  1 
ATOM   697  C CD1 . LEU A 1 85  ? -26.15  -14.734 43.111  1   30.5   ? 255 LEU D CD1 1 
ATOM   698  C CD2 . LEU A 1 85  ? -24.366 -15.622 41.566  1   31.03  ? 255 LEU D CD2 1 
ATOM   699  N N   . VAL A 1 86  ? -28.667 -17     39.528  1   29.79  ? 256 VAL D N   1 
ATOM   700  C CA  . VAL A 1 86  ? -29.351 -16.384 38.401  1   29.71  ? 256 VAL D CA  1 
ATOM   701  C C   . VAL A 1 86  ? -30.796 -16.068 38.795  1   31.57  ? 256 VAL D C   1 
ATOM   702  O O   . VAL A 1 86  ? -31.278 -14.954 38.568  1   30.2   ? 256 VAL D O   1 
ATOM   703  C CB  . VAL A 1 86  ? -29.317 -17.25  37.132  1   26.09  ? 256 VAL D CB  1 
ATOM   704  C CG1 . VAL A 1 86  ? -30.252 -16.663 36.095  1   23.22  ? 256 VAL D CG1 1 
ATOM   705  C CG2 . VAL A 1 86  ? -27.9   -17.424 36.605  1   25.27  ? 256 VAL D CG2 1 
ATOM   706  N N   . GLY A 1 87  ? -31.469 -17.078 39.377  1   32.89  ? 257 GLY D N   1 
ATOM   707  C CA  . GLY A 1 87  ? -32.882 -17.025 39.706  1   31     ? 257 GLY D CA  1 
ATOM   708  C C   . GLY A 1 87  ? -33.145 -16.001 40.806  1   32.64  ? 257 GLY D C   1 
ATOM   709  O O   . GLY A 1 87  ? -34.157 -15.312 40.764  1   35.5   ? 257 GLY D O   1 
ATOM   710  N N   . THR A 1 88  ? -32.242 -15.893 41.789  1   31.77  ? 258 THR D N   1 
ATOM   711  C CA  . THR A 1 88  ? -32.409 -14.907 42.848  1   32.07  ? 258 THR D CA  1 
ATOM   712  C C   . THR A 1 88  ? -32.41  -13.528 42.193  1   31.83  ? 258 THR D C   1 
ATOM   713  O O   . THR A 1 88  ? -33.358 -12.758 42.353  1   31.05  ? 258 THR D O   1 
ATOM   714  C CB  . THR A 1 88  ? -31.33  -15.052 43.925  1   33.22  ? 258 THR D CB  1 
ATOM   715  O OG1 . THR A 1 88  ? -31.501 -16.345 44.491  1   38.82  ? 258 THR D OG1 1 
ATOM   716  C CG2 . THR A 1 88  ? -31.488 -14.104 45.099  1   32.66  ? 258 THR D CG2 1 
ATOM   717  N N   . ALA A 1 89  ? -31.349 -13.274 41.415  1   30.92  ? 259 ALA D N   1 
ATOM   718  C CA  . ALA A 1 89  ? -31.114 -12.042 40.682  1   29.89  ? 259 ALA D CA  1 
ATOM   719  C C   . ALA A 1 89  ? -32.336 -11.64  39.876  1   29.22  ? 259 ALA D C   1 
ATOM   720  O O   . ALA A 1 89  ? -32.623 -10.455 39.778  1   32.36  ? 259 ALA D O   1 
ATOM   721  C CB  . ALA A 1 89  ? -29.952 -12.243 39.749  1   31.53  ? 259 ALA D CB  1 
ATOM   722  N N   . ALA A 1 90  ? -33.022 -12.625 39.288  1   27.69  ? 260 ALA D N   1 
ATOM   723  C CA  . ALA A 1 90  ? -34.17  -12.387 38.432  1   27.08  ? 260 ALA D CA  1 
ATOM   724  C C   . ALA A 1 90  ? -35.395 -12.042 39.272  1   29.35  ? 260 ALA D C   1 
ATOM   725  O O   . ALA A 1 90  ? -36.159 -11.144 38.932  1   32.55  ? 260 ALA D O   1 
ATOM   726  C CB  . ALA A 1 90  ? -34.418 -13.603 37.577  1   25.85  ? 260 ALA D CB  1 
ATOM   727  N N   . MET A 1 91  ? -35.597 -12.772 40.371  1   29.87  ? 261 MET D N   1 
ATOM   728  C CA  . MET A 1 91  ? -36.73  -12.498 41.234  1   31.62  ? 261 MET D CA  1 
ATOM   729  C C   . MET A 1 91  ? -36.664 -11.048 41.711  1   31.48  ? 261 MET D C   1 
ATOM   730  O O   . MET A 1 91  ? -37.687 -10.37  41.766  1   32.55  ? 261 MET D O   1 
ATOM   731  C CB  . MET A 1 91  ? -36.736 -13.44  42.444  1   32.95  ? 261 MET D CB  1 
ATOM   732  C CG  . MET A 1 91  ? -38.104 -13.619 43.072  1   34.35  ? 261 MET D CG  1 
ATOM   733  S SD  . MET A 1 91  ? -39.302 -14.2   41.85   1   36.19  ? 261 MET D SD  1 
ATOM   734  C CE  . MET A 1 91  ? -40.803 -14.201 42.833  1   36.17  ? 261 MET D CE  1 
ATOM   735  N N   . LEU A 1 92  ? -35.443 -10.622 42.065  1   30.95  ? 262 LEU D N   1 
ATOM   736  C CA  . LEU A 1 92  ? -35.117 -9.289  42.525  1   30.45  ? 262 LEU D CA  1 
ATOM   737  C C   . LEU A 1 92  ? -35.448 -8.296  41.418  1   31.55  ? 262 LEU D C   1 
ATOM   738  O O   . LEU A 1 92  ? -36.088 -7.261  41.653  1   33.31  ? 262 LEU D O   1 
ATOM   739  C CB  . LEU A 1 92  ? -33.635 -9.214  42.895  1   29.85  ? 262 LEU D CB  1 
ATOM   740  C CG  . LEU A 1 92  ? -33.112 -7.819  43.281  1   30.03  ? 262 LEU D CG  1 
ATOM   741  C CD1 . LEU A 1 92  ? -33.757 -7.326  44.555  1   31.49  ? 262 LEU D CD1 1 
ATOM   742  C CD2 . LEU A 1 92  ? -31.612 -7.749  43.424  1   28.83  ? 262 LEU D CD2 1 
ATOM   743  N N   . LEU A 1 93  ? -34.977 -8.608  40.208  1   29.03  ? 263 LEU D N   1 
ATOM   744  C CA  . LEU A 1 93  ? -35.233 -7.718  39.099  1   29.2   ? 263 LEU D CA  1 
ATOM   745  C C   . LEU A 1 93  ? -36.736 -7.621  38.885  1   30.43  ? 263 LEU D C   1 
ATOM   746  O O   . LEU A 1 93  ? -37.265 -6.513  38.813  1   34.86  ? 263 LEU D O   1 
ATOM   747  C CB  . LEU A 1 93  ? -34.479 -8.198  37.874  1   29.67  ? 263 LEU D CB  1 
ATOM   748  C CG  . LEU A 1 93  ? -33     -7.816  37.85   1   32.34  ? 263 LEU D CG  1 
ATOM   749  C CD1 . LEU A 1 93  ? -32.253 -8.578  36.768  1   31.99  ? 263 LEU D CD1 1 
ATOM   750  C CD2 . LEU A 1 93  ? -32.864 -6.306  37.627  1   36.65  ? 263 LEU D CD2 1 
ATOM   751  N N   . ALA A 1 94  ? -37.42  -8.769  38.866  1   28.02  ? 264 ALA D N   1 
ATOM   752  C CA  . ALA A 1 94  ? -38.853 -8.78   38.627  1   27.66  ? 264 ALA D CA  1 
ATOM   753  C C   . ALA A 1 94  ? -39.581 -8.027  39.727  1   27.69  ? 264 ALA D C   1 
ATOM   754  O O   . ALA A 1 94  ? -40.571 -7.356  39.459  1   28.43  ? 264 ALA D O   1 
ATOM   755  C CB  . ALA A 1 94  ? -39.375 -10.183 38.532  1   28.27  ? 264 ALA D CB  1 
ATOM   756  N N   . SER A 1 95  ? -39.084 -8.162  40.957  1   26.46  ? 265 SER D N   1 
ATOM   757  C CA  . SER A 1 95  ? -39.694 -7.491  42.085  1   26.8   ? 265 SER D CA  1 
ATOM   758  C C   . SER A 1 95  ? -39.569 -5.983  41.896  1   28.61  ? 265 SER D C   1 
ATOM   759  O O   . SER A 1 95  ? -40.553 -5.258  42.061  1   30.22  ? 265 SER D O   1 
ATOM   760  C CB  . SER A 1 95  ? -39.09  -7.933  43.375  1   26.12  ? 265 SER D CB  1 
ATOM   761  O OG  . SER A 1 95  ? -39.385 -9.295  43.626  1   26.88  ? 265 SER D OG  1 
ATOM   762  N N   . LYS A 1 96  ? -38.355 -5.52   41.549  1   28.29  ? 266 LYS D N   1 
ATOM   763  C CA  . LYS A 1 96  ? -38.086 -4.099  41.382  1   27.42  ? 266 LYS D CA  1 
ATOM   764  C C   . LYS A 1 96  ? -38.952 -3.53   40.265  1   27.86  ? 266 LYS D C   1 
ATOM   765  O O   . LYS A 1 96  ? -39.469 -2.428  40.4    1   28.31  ? 266 LYS D O   1 
ATOM   766  C CB  . LYS A 1 96  ? -36.611 -3.881  41.051  1   26.04  ? 266 LYS D CB  1 
ATOM   767  C CG  . LYS A 1 96  ? -35.729 -3.77   42.292  1   25.68  ? 266 LYS D CG  1 
ATOM   768  C CD  . LYS A 1 96  ? -34.258 -3.738  41.899  1   24.08  ? 266 LYS D CD  1 
ATOM   769  C CE  . LYS A 1 96  ? -33.315 -3.633  43.036  1   23.91  ? 266 LYS D CE  1 
ATOM   770  N NZ  . LYS A 1 96  ? -32.022 -3.179  42.54   1   23.05  ? 266 LYS D NZ  1 
ATOM   771  N N   . PHE A 1 97  ? -39.109 -4.304  39.184  1   27.54  ? 267 PHE D N   1 
ATOM   772  C CA  . PHE A 1 97  ? -39.93  -3.903  38.054  1   28.27  ? 267 PHE D CA  1 
ATOM   773  C C   . PHE A 1 97  ? -41.397 -3.772  38.462  1   29.5   ? 267 PHE D C   1 
ATOM   774  O O   . PHE A 1 97  ? -42.047 -2.805  38.064  1   29.59  ? 267 PHE D O   1 
ATOM   775  C CB  . PHE A 1 97  ? -39.795 -4.858  36.864  1   26.53  ? 267 PHE D CB  1 
ATOM   776  C CG  . PHE A 1 97  ? -40.565 -4.442  35.612  1   27.9   ? 267 PHE D CG  1 
ATOM   777  C CD1 . PHE A 1 97  ? -39.991 -3.595  34.661  1   29     ? 267 PHE D CD1 1 
ATOM   778  C CD2 . PHE A 1 97  ? -41.857 -4.903  35.357  1   28.07  ? 267 PHE D CD2 1 
ATOM   779  C CE1 . PHE A 1 97  ? -40.679 -3.22   33.5    1   28.56  ? 267 PHE D CE1 1 
ATOM   780  C CE2 . PHE A 1 97  ? -42.535 -4.525  34.194  1   28.82  ? 267 PHE D CE2 1 
ATOM   781  C CZ  . PHE A 1 97  ? -41.953 -3.685  33.263  1   28.09  ? 267 PHE D CZ  1 
ATOM   782  N N   . GLU A 1 98  ? -41.905 -4.754  39.23   1   30.36  ? 268 GLU D N   1 
ATOM   783  C CA  . GLU A 1 98  ? -43.337 -5.038  39.269  1   31.53  ? 268 GLU D CA  1 
ATOM   784  C C   . GLU A 1 98  ? -44.004 -4.659  40.591  1   32.31  ? 268 GLU D C   1 
ATOM   785  O O   . GLU A 1 98  ? -45.161 -4.262  40.571  1   35.63  ? 268 GLU D O   1 
ATOM   786  C CB  . GLU A 1 98  ? -43.615 -6.5    38.926  1   31.56  ? 268 GLU D CB  1 
ATOM   787  C CG  . GLU A 1 98  ? -45.074 -6.814  38.594  1   33.85  ? 268 GLU D CG  1 
ATOM   788  C CD  . GLU A 1 98  ? -45.696 -5.977  37.484  1   35.47  ? 268 GLU D CD  1 
ATOM   789  O OE1 . GLU A 1 98  ? -44.942 -5.601  36.565  1   34.76  ? 268 GLU D OE1 1 
ATOM   790  O OE2 . GLU A 1 98  ? -46.93  -5.748  37.5    1   36.5   ? 268 GLU D OE2 1 
ATOM   791  N N   . GLU A 1 99  ? -43.309 -4.792  41.726  1   31.46  ? 269 GLU D N   1 
ATOM   792  C CA  . GLU A 1 99  ? -43.962 -4.638  43.015  1   33.59  ? 269 GLU D CA  1 
ATOM   793  C C   . GLU A 1 99  ? -43.926 -3.188  43.479  1   35.73  ? 269 GLU D C   1 
ATOM   794  O O   . GLU A 1 99  ? -42.987 -2.46   43.144  1   36.38  ? 269 GLU D O   1 
ATOM   795  C CB  . GLU A 1 99  ? -43.196 -5.424  44.068  1   34.81  ? 269 GLU D CB  1 
ATOM   796  C CG  . GLU A 1 99  ? -43.22  -6.922  43.797  1   36.98  ? 269 GLU D CG  1 
ATOM   797  C CD  . GLU A 1 99  ? -44.584 -7.524  44.042  1   39.96  ? 269 GLU D CD  1 
ATOM   798  O OE1 . GLU A 1 99  ? -45.281 -6.997  44.928  1   43.25  ? 269 GLU D OE1 1 
ATOM   799  O OE2 . GLU A 1 99  ? -44.917 -8.527  43.39   1   40.8   ? 269 GLU D OE2 1 
ATOM   800  N N   . ILE A 1 100 ? -44.936 -2.802  44.278  1   36.14  ? 270 ILE D N   1 
ATOM   801  C CA  . ILE A 1 100 ? -45.014 -1.465  44.855  1   37.33  ? 270 ILE D CA  1 
ATOM   802  C C   . ILE A 1 100 ? -43.975 -1.34   45.967  1   39.37  ? 270 ILE D C   1 
ATOM   803  O O   . ILE A 1 100 ? -43.359 -0.286  46.154  1   40.42  ? 270 ILE D O   1 
ATOM   804  C CB  . ILE A 1 100 ? -46.421 -1.178  45.408  1   37.35  ? 270 ILE D CB  1 
ATOM   805  C CG1 . ILE A 1 100 ? -47.476 -1.166  44.315  1   36.72  ? 270 ILE D CG1 1 
ATOM   806  C CG2 . ILE A 1 100 ? -46.433 0.111   46.228  1   37.76  ? 270 ILE D CG2 1 
ATOM   807  C CD1 . ILE A 1 100 ? -48.893 -1.149  44.856  1   38.3   ? 270 ILE D CD1 1 
ATOM   808  N N   . TYR A 1 101 ? -43.84  -2.441  46.715  1   41.41  ? 271 TYR D N   1 
ATOM   809  C CA  . TYR A 1 101 ? -43.014 -2.55   47.909  1   42.1   ? 271 TYR D CA  1 
ATOM   810  C C   . TYR A 1 101 ? -42.159 -3.822  47.793  1   41.91  ? 271 TYR D C   1 
ATOM   811  O O   . TYR A 1 101 ? -42.408 -4.817  48.484  1   42.46  ? 271 TYR D O   1 
ATOM   812  C CB  . TYR A 1 101 ? -43.971 -2.644  49.1    1   42.52  ? 271 TYR D CB  1 
ATOM   813  C CG  . TYR A 1 101 ? -44.865 -1.444  49.368  1   45.12  ? 271 TYR D CG  1 
ATOM   814  C CD1 . TYR A 1 101 ? -44.334 -0.229  49.789  1   47.49  ? 271 TYR D CD1 1 
ATOM   815  C CD2 . TYR A 1 101 ? -46.249 -1.549  49.278  1   46.18  ? 271 TYR D CD2 1 
ATOM   816  C CE1 . TYR A 1 101 ? -45.155 0.853   50.073  1   50.44  ? 271 TYR D CE1 1 
ATOM   817  C CE2 . TYR A 1 101 ? -47.083 -0.474  49.565  1   48.37  ? 271 TYR D CE2 1 
ATOM   818  C CZ  . TYR A 1 101 ? -46.533 0.735   49.955  1   51.06  ? 271 TYR D CZ  1 
ATOM   819  O OH  . TYR A 1 101 ? -47.321 1.82    50.24   1   55     ? 271 TYR D OH  1 
ATOM   820  N N   . PRO A 1 102 ? -41.15  -3.87   46.885  1   38.43  ? 272 PRO D N   1 
ATOM   821  C CA  . PRO A 1 102 ? -40.38  -5.093  46.679  1   36.04  ? 272 PRO D CA  1 
ATOM   822  C C   . PRO A 1 102 ? -39.584 -5.383  47.95   1   38.58  ? 272 PRO D C   1 
ATOM   823  O O   . PRO A 1 102 ? -39.298 -4.484  48.738  1   40.45  ? 272 PRO D O   1 
ATOM   824  C CB  . PRO A 1 102 ? -39.484 -4.737  45.503  1   33.19  ? 272 PRO D CB  1 
ATOM   825  C CG  . PRO A 1 102 ? -39.351 -3.257  45.577  1   34.43  ? 272 PRO D CG  1 
ATOM   826  C CD  . PRO A 1 102 ? -40.696 -2.755  46.039  1   36.64  ? 272 PRO D CD  1 
ATOM   827  N N   . PRO A 1 103 ? -39.201 -6.654  48.207  1   38.27  ? 273 PRO D N   1 
ATOM   828  C CA  . PRO A 1 103 ? -38.398 -6.97   49.385  1   38.63  ? 273 PRO D CA  1 
ATOM   829  C C   . PRO A 1 103 ? -37.032 -6.363  49.122  1   38.89  ? 273 PRO D C   1 
ATOM   830  O O   . PRO A 1 103 ? -36.666 -6.073  47.988  1   36.27  ? 273 PRO D O   1 
ATOM   831  C CB  . PRO A 1 103 ? -38.342 -8.503  49.42   1   38.33  ? 273 PRO D CB  1 
ATOM   832  C CG  . PRO A 1 103 ? -39.354 -8.953  48.387  1   37.32  ? 273 PRO D CG  1 
ATOM   833  C CD  . PRO A 1 103 ? -39.504 -7.832  47.381  1   35.83  ? 273 PRO D CD  1 
ATOM   834  N N   . GLU A 1 104 ? -36.271 -6.212  50.198  1   44.39  ? 274 GLU D N   1 
ATOM   835  C CA  . GLU A 1 104 ? -34.953 -5.608  50.112  1   49.76  ? 274 GLU D CA  1 
ATOM   836  C C   . GLU A 1 104 ? -33.95  -6.592  49.53   1   49.09  ? 274 GLU D C   1 
ATOM   837  O O   . GLU A 1 104 ? -34.223 -7.786  49.365  1   50.87  ? 274 GLU D O   1 
ATOM   838  C CB  . GLU A 1 104 ? -34.586 -5.119  51.51   1   56.82  ? 274 GLU D CB  1 
ATOM   839  C CG  . GLU A 1 104 ? -35.782 -4.412  52.148  1   69.45  ? 274 GLU D CG  1 
ATOM   840  C CD  . GLU A 1 104 ? -35.533 -3.23   53.058  1   85.53  ? 274 GLU D CD  1 
ATOM   841  O OE1 . GLU A 1 104 ? -35.947 -2.105  52.666  1   90.24  ? 274 GLU D OE1 1 
ATOM   842  O OE2 . GLU A 1 104 ? -34.922 -3.46   54.131  1   96.01  ? 274 GLU D OE2 1 
ATOM   843  N N   . VAL A 1 105 ? -32.772 -6.075  49.203  1   46.87  ? 275 VAL D N   1 
ATOM   844  C CA  . VAL A 1 105 ? -31.795 -6.969  48.613  1   44.25  ? 275 VAL D CA  1 
ATOM   845  C C   . VAL A 1 105 ? -31.389 -7.996  49.667  1   44.59  ? 275 VAL D C   1 
ATOM   846  O O   . VAL A 1 105 ? -31.169 -9.163  49.348  1   44.15  ? 275 VAL D O   1 
ATOM   847  C CB  . VAL A 1 105 ? -30.605 -6.192  48.024  1   44.7   ? 275 VAL D CB  1 
ATOM   848  C CG1 . VAL A 1 105 ? -29.454 -7.106  47.645  1   46.03  ? 275 VAL D CG1 1 
ATOM   849  C CG2 . VAL A 1 105 ? -31.044 -5.375  46.822  1   43.02  ? 275 VAL D CG2 1 
ATOM   850  N N   . ALA A 1 106 ? -31.322 -7.545  50.927  1   45.6   ? 276 ALA D N   1 
ATOM   851  C CA  . ALA A 1 106 ? -30.959 -8.402  52.043  1   43.42  ? 276 ALA D CA  1 
ATOM   852  C C   . ALA A 1 106 ? -31.882 -9.613  52.111  1   43.26  ? 276 ALA D C   1 
ATOM   853  O O   . ALA A 1 106 ? -31.415 -10.711 52.4    1   43.64  ? 276 ALA D O   1 
ATOM   854  C CB  . ALA A 1 106 ? -30.956 -7.62   53.316  1   44.17  ? 276 ALA D CB  1 
ATOM   855  N N   . GLU A 1 107 ? -33.169 -9.418  51.795  1   43.26  ? 277 GLU D N   1 
ATOM   856  C CA  . GLU A 1 107 ? -34.128 -10.506 51.892  1   45.33  ? 277 GLU D CA  1 
ATOM   857  C C   . GLU A 1 107 ? -33.911 -11.523 50.775  1   44.1   ? 277 GLU D C   1 
ATOM   858  O O   . GLU A 1 107 ? -34.198 -12.706 50.938  1   43.15  ? 277 GLU D O   1 
ATOM   859  C CB  . GLU A 1 107 ? -35.546 -10.002 52.104  1   47.07  ? 277 GLU D CB  1 
ATOM   860  C CG  . GLU A 1 107 ? -35.819 -9.778  53.59   1   55.3   ? 277 GLU D CG  1 
ATOM   861  C CD  . GLU A 1 107 ? -37.11  -9.032  53.908  1   65.75  ? 277 GLU D CD  1 
ATOM   862  O OE1 . GLU A 1 107 ? -37.674 -9.353  54.998  1   73.06  ? 277 GLU D OE1 1 
ATOM   863  O OE2 . GLU A 1 107 ? -37.56  -8.153  53.092  1   63.71  ? 277 GLU D OE2 1 
ATOM   864  N N   . PHE A 1 108 ? -33.344 -11.076 49.656  1   43.98  ? 278 PHE D N   1 
ATOM   865  C CA  . PHE A 1 108 ? -33.02  -12.026 48.608  1   42.28  ? 278 PHE D CA  1 
ATOM   866  C C   . PHE A 1 108 ? -31.773 -12.827 48.969  1   44.87  ? 278 PHE D C   1 
ATOM   867  O O   . PHE A 1 108 ? -31.535 -13.871 48.368  1   51.16  ? 278 PHE D O   1 
ATOM   868  C CB  . PHE A 1 108 ? -32.908 -11.354 47.244  1   38.28  ? 278 PHE D CB  1 
ATOM   869  C CG  . PHE A 1 108 ? -34.273 -10.969 46.699  1   37.69  ? 278 PHE D CG  1 
ATOM   870  C CD1 . PHE A 1 108 ? -35.056 -11.915 46.036  1   37.04  ? 278 PHE D CD1 1 
ATOM   871  C CD2 . PHE A 1 108 ? -34.769 -9.68   46.861  1   36.87  ? 278 PHE D CD2 1 
ATOM   872  C CE1 . PHE A 1 108 ? -36.3   -11.586 45.524  1   35.36  ? 278 PHE D CE1 1 
ATOM   873  C CE2 . PHE A 1 108 ? -36.009 -9.358  46.34   1   37.45  ? 278 PHE D CE2 1 
ATOM   874  C CZ  . PHE A 1 108 ? -36.766 -10.311 45.666  1   35.56  ? 278 PHE D CZ  1 
ATOM   875  N N   . VAL A 1 109 ? -30.981 -12.341 49.93   1   43.79  ? 279 VAL D N   1 
ATOM   876  C CA  . VAL A 1 109 ? -29.76  -13.038 50.303  1   43.71  ? 279 VAL D CA  1 
ATOM   877  C C   . VAL A 1 109 ? -30.088 -14.006 51.43   1   48.66  ? 279 VAL D C   1 
ATOM   878  O O   . VAL A 1 109 ? -29.401 -15.012 51.605  1   53.85  ? 279 VAL D O   1 
ATOM   879  C CB  . VAL A 1 109 ? -28.627 -12.088 50.725  1   41.38  ? 279 VAL D CB  1 
ATOM   880  C CG1 . VAL A 1 109 ? -27.361 -12.853 51.089  1   40.76  ? 279 VAL D CG1 1 
ATOM   881  C CG2 . VAL A 1 109 ? -28.361 -11.032 49.667  1   39.72  ? 279 VAL D CG2 1 
ATOM   882  N N   . TYR A 1 110 ? -31.115 -13.653 52.21   1   50.9   ? 280 TYR D N   1 
ATOM   883  C CA  . TYR A 1 110 ? -31.584 -14.49  53.293  1   51.99  ? 280 TYR D CA  1 
ATOM   884  C C   . TYR A 1 110 ? -32.187 -15.767 52.711  1   50.75  ? 280 TYR D C   1 
ATOM   885  O O   . TYR A 1 110 ? -31.887 -16.837 53.218  1   52.81  ? 280 TYR D O   1 
ATOM   886  C CB  . TYR A 1 110 ? -32.553 -13.697 54.165  1   56.12  ? 280 TYR D CB  1 
ATOM   887  C CG  . TYR A 1 110 ? -33.164 -14.527 55.281  1   65.07  ? 280 TYR D CG  1 
ATOM   888  C CD1 . TYR A 1 110 ? -32.512 -14.66  56.502  1   69.46  ? 280 TYR D CD1 1 
ATOM   889  C CD2 . TYR A 1 110 ? -34.392 -15.169 55.114  1   67.47  ? 280 TYR D CD2 1 
ATOM   890  C CE1 . TYR A 1 110 ? -33.068 -15.412 57.526  1   74.9   ? 280 TYR D CE1 1 
ATOM   891  C CE2 . TYR A 1 110 ? -34.95  -15.934 56.126  1   73.59  ? 280 TYR D CE2 1 
ATOM   892  C CZ  . TYR A 1 110 ? -34.287 -16.052 57.339  1   77.47  ? 280 TYR D CZ  1 
ATOM   893  O OH  . TYR A 1 110 ? -34.837 -16.79  58.355  1   80.39  ? 280 TYR D OH  1 
ATOM   894  N N   . ILE A 1 111 ? -32.982 -15.671 51.629  1   47.47  ? 281 ILE D N   1 
ATOM   895  C CA  . ILE A 1 111 ? -33.663 -16.842 51.085  1   47.41  ? 281 ILE D CA  1 
ATOM   896  C C   . ILE A 1 111 ? -32.702 -17.811 50.398  1   49.28  ? 281 ILE D C   1 
ATOM   897  O O   . ILE A 1 111 ? -33.112 -18.921 50.086  1   50.92  ? 281 ILE D O   1 
ATOM   898  C CB  . ILE A 1 111 ? -34.815 -16.517 50.117  1   44.21  ? 281 ILE D CB  1 
ATOM   899  C CG1 . ILE A 1 111 ? -34.427 -15.426 49.136  1   43.85  ? 281 ILE D CG1 1 
ATOM   900  C CG2 . ILE A 1 111 ? -36.116 -16.227 50.851  1   42.19  ? 281 ILE D CG2 1 
ATOM   901  C CD1 . ILE A 1 111 ? -35.493 -15.098 48.107  1   45.03  ? 281 ILE D CD1 1 
ATOM   902  N N   . THR A 1 112 ? -31.463 -17.409 50.102  1   50.89  ? 282 THR D N   1 
ATOM   903  C CA  . THR A 1 112 ? -30.543 -18.343 49.464  1   53.35  ? 282 THR D CA  1 
ATOM   904  C C   . THR A 1 112 ? -29.794 -19.162 50.509  1   59.01  ? 282 THR D C   1 
ATOM   905  O O   . THR A 1 112 ? -28.855 -19.868 50.146  1   61.53  ? 282 THR D O   1 
ATOM   906  C CB  . THR A 1 112 ? -29.53  -17.624 48.579  1   53.58  ? 282 THR D CB  1 
ATOM   907  O OG1 . THR A 1 112 ? -28.764 -16.845 49.495  1   56.42  ? 282 THR D OG1 1 
ATOM   908  C CG2 . THR A 1 112 ? -30.168 -16.809 47.471  1   47.43  ? 282 THR D CG2 1 
ATOM   909  N N   . ASP A 1 113 ? -30.177 -19.007 51.788  1   65.53  ? 283 ASP D N   1 
ATOM   910  C CA  . ASP A 1 113 ? -29.56  -19.672 52.93   1   72.35  ? 283 ASP D CA  1 
ATOM   911  C C   . ASP A 1 113 ? -28.072 -19.357 52.964  1   69.93  ? 283 ASP D C   1 
ATOM   912  O O   . ASP A 1 113 ? -27.258 -20.197 53.34   1   65.5   ? 283 ASP D O   1 
ATOM   913  C CB  . ASP A 1 113 ? -29.869 -21.161 52.979  1   85.98  ? 283 ASP D CB  1 
ATOM   914  C CG  . ASP A 1 113 ? -31.306 -21.529 53.33   1   97.19  ? 283 ASP D CG  1 
ATOM   915  O OD1 . ASP A 1 113 ? -32.082 -20.62  53.722  1   89.46  ? 283 ASP D OD1 1 
ATOM   916  O OD2 . ASP A 1 113 ? -31.638 -22.734 53.223  1   108.16 ? 283 ASP D OD2 1 
ATOM   917  N N   . ASP A 1 114 ? -27.749 -18.123 52.563  1   73.84  ? 284 ASP D N   1 
ATOM   918  C CA  . ASP A 1 114 ? -26.377 -17.64  52.519  1   81.35  ? 284 ASP D CA  1 
ATOM   919  C C   . ASP A 1 114 ? -25.494 -18.629 51.757  1   78.6   ? 284 ASP D C   1 
ATOM   920  O O   . ASP A 1 114 ? -24.359 -18.901 52.143  1   79.88  ? 284 ASP D O   1 
ATOM   921  C CB  . ASP A 1 114 ? -25.904 -17.229 53.907  1   90.6   ? 284 ASP D CB  1 
ATOM   922  C CG  . ASP A 1 114 ? -26.707 -16.09  54.528  1   90.53  ? 284 ASP D CG  1 
ATOM   923  O OD1 . ASP A 1 114 ? -27.102 -15.179 53.757  1   88.08  ? 284 ASP D OD1 1 
ATOM   924  O OD2 . ASP A 1 114 ? -26.923 -16.119 55.768  1   85.71  ? 284 ASP D OD2 1 
ATOM   925  N N   . THR A 1 115 ? -26.045 -19.176 50.669  1   72.58  ? 285 THR D N   1 
ATOM   926  C CA  . THR A 1 115 ? -25.255 -19.832 49.64   1   64.63  ? 285 THR D CA  1 
ATOM   927  C C   . THR A 1 115 ? -24.404 -18.76  48.947  1   57.48  ? 285 THR D C   1 
ATOM   928  O O   . THR A 1 115 ? -23.214 -18.964 48.716  1   57.87  ? 285 THR D O   1 
ATOM   929  C CB  . THR A 1 115 ? -26.205 -20.598 48.708  1   62.96  ? 285 THR D CB  1 
ATOM   930  O OG1 . THR A 1 115 ? -26.687 -21.73  49.425  1   62.42  ? 285 THR D OG1 1 
ATOM   931  C CG2 . THR A 1 115 ? -25.551 -21.104 47.437  1   60.21  ? 285 THR D CG2 1 
ATOM   932  N N   . TYR A 1 116 ? -25.008 -17.59  48.688  1   49.91  ? 286 TYR D N   1 
ATOM   933  C CA  . TYR A 1 116 ? -24.334 -16.473 48.046  1   46.11  ? 286 TYR D CA  1 
ATOM   934  C C   . TYR A 1 116 ? -24.278 -15.25  48.971  1   46.59  ? 286 TYR D C   1 
ATOM   935  O O   . TYR A 1 116 ? -25.091 -15.13  49.885  1   50.65  ? 286 TYR D O   1 
ATOM   936  C CB  . TYR A 1 116 ? -25.116 -16.162 46.771  1   42.92  ? 286 TYR D CB  1 
ATOM   937  C CG  . TYR A 1 116 ? -25.468 -17.374 45.921  1   42.04  ? 286 TYR D CG  1 
ATOM   938  C CD1 . TYR A 1 116 ? -24.479 -18.081 45.242  1   43.77  ? 286 TYR D CD1 1 
ATOM   939  C CD2 . TYR A 1 116 ? -26.784 -17.797 45.772  1   40.2   ? 286 TYR D CD2 1 
ATOM   940  C CE1 . TYR A 1 116 ? -24.783 -19.175 44.442  1   42.13  ? 286 TYR D CE1 1 
ATOM   941  C CE2 . TYR A 1 116 ? -27.097 -18.892 44.978  1   40.08  ? 286 TYR D CE2 1 
ATOM   942  C CZ  . TYR A 1 116 ? -26.099 -19.593 44.307  1   40.06  ? 286 TYR D CZ  1 
ATOM   943  O OH  . TYR A 1 116 ? -26.391 -20.675 43.499  1   35.96  ? 286 TYR D OH  1 
ATOM   944  N N   . THR A 1 117 ? -23.303 -14.352 48.74   1   45.07  ? 287 THR D N   1 
ATOM   945  C CA  . THR A 1 117 ? -23.161 -13.082 49.457  1   47.19  ? 287 THR D CA  1 
ATOM   946  C C   . THR A 1 117 ? -24.098 -12.029 48.864  1   45.25  ? 287 THR D C   1 
ATOM   947  O O   . THR A 1 117 ? -24.627 -12.214 47.78   1   46.99  ? 287 THR D O   1 
ATOM   948  C CB  . THR A 1 117 ? -21.736 -12.53  49.385  1   48.22  ? 287 THR D CB  1 
ATOM   949  O OG1 . THR A 1 117 ? -21.551 -12.076 48.045  1   52.84  ? 287 THR D OG1 1 
ATOM   950  C CG2 . THR A 1 117 ? -20.673 -13.531 49.785  1   46.76  ? 287 THR D CG2 1 
ATOM   951  N N   . LYS A 1 118 ? -24.241 -10.883 49.532  1   43.6   ? 288 LYS D N   1 
ATOM   952  C CA  . LYS A 1 118 ? -25.035 -9.8    48.982  1   41.96  ? 288 LYS D CA  1 
ATOM   953  C C   . LYS A 1 118 ? -24.376 -9.263  47.71   1   42.77  ? 288 LYS D C   1 
ATOM   954  O O   . LYS A 1 118 ? -25.042 -8.814  46.777  1   41.49  ? 288 LYS D O   1 
ATOM   955  C CB  . LYS A 1 118 ? -25.171 -8.729  50.069  1   44.8   ? 288 LYS D CB  1 
ATOM   956  C CG  . LYS A 1 118 ? -26.029 -7.511  49.77   1   45.1   ? 288 LYS D CG  1 
ATOM   957  C CD  . LYS A 1 118 ? -26.14  -6.621  51.008  1   50.55  ? 288 LYS D CD  1 
ATOM   958  C CE  . LYS A 1 118 ? -27.149 -5.509  50.897  1   52.71  ? 288 LYS D CE  1 
ATOM   959  N NZ  . LYS A 1 118 ? -27.159 -4.667  52.097  1   54.95  ? 288 LYS D NZ  1 
ATOM   960  N N   . LYS A 1 119 ? -23.051 -9.313  47.641  1   46.66  ? 289 LYS D N   1 
ATOM   961  C CA  . LYS A 1 119 ? -22.348 -8.706  46.478  1   47.1   ? 289 LYS D CA  1 
ATOM   962  C C   . LYS A 1 119 ? -22.401 -9.634  45.265  1   41.71  ? 289 LYS D C   1 
ATOM   963  O O   . LYS A 1 119 ? -22.195 -9.138  44.162  1   40.19  ? 289 LYS D O   1 
ATOM   964  C CB  . LYS A 1 119 ? -20.896 -8.356  46.808  1   54.43  ? 289 LYS D CB  1 
ATOM   965  C CG  . LYS A 1 119 ? -20.419 -7.051  46.192  1   59.85  ? 289 LYS D CG  1 
ATOM   966  C CD  . LYS A 1 119 ? -18.909 -6.96   46.016  1   65.12  ? 289 LYS D CD  1 
ATOM   967  C CE  . LYS A 1 119 ? -18.436 -5.545  46.103  1   65.33  ? 289 LYS D CE  1 
ATOM   968  N NZ  . LYS A 1 119 ? -19.412 -4.612  45.536  1   66.09  ? 289 LYS D NZ  1 
ATOM   969  N N   . GLN A 1 120 ? -22.636 -10.925 45.471  1   38.12  ? 290 GLN D N   1 
ATOM   970  C CA  . GLN A 1 120 ? -22.814 -11.804 44.33   1   35.9   ? 290 GLN D CA  1 
ATOM   971  C C   . GLN A 1 120 ? -24.206 -11.596 43.746  1   36.35  ? 290 GLN D C   1 
ATOM   972  O O   . GLN A 1 120 ? -24.396 -11.578 42.53   1   36.8   ? 290 GLN D O   1 
ATOM   973  C CB  . GLN A 1 120 ? -22.66  -13.264 44.726  1   33.91  ? 290 GLN D CB  1 
ATOM   974  C CG  . GLN A 1 120 ? -21.224 -13.662 45.025  1   34.34  ? 290 GLN D CG  1 
ATOM   975  C CD  . GLN A 1 120 ? -21.203 -15.02  45.671  1   35.87  ? 290 GLN D CD  1 
ATOM   976  O OE1 . GLN A 1 120 ? -21.425 -15.149 46.876  1   39.01  ? 290 GLN D OE1 1 
ATOM   977  N NE2 . GLN A 1 120 ? -20.998 -16.054 44.872  1   35.5   ? 290 GLN D NE2 1 
ATOM   978  N N   . VAL A 1 121 ? -25.186 -11.446 44.636  1   36.86  ? 291 VAL D N   1 
ATOM   979  C CA  . VAL A 1 121 ? -26.553 -11.209 44.211  1   35.5   ? 291 VAL D CA  1 
ATOM   980  C C   . VAL A 1 121 ? -26.612 -9.919  43.401  1   35.63  ? 291 VAL D C   1 
ATOM   981  O O   . VAL A 1 121 ? -27.308 -9.849  42.393  1   34.38  ? 291 VAL D O   1 
ATOM   982  C CB  . VAL A 1 121 ? -27.487 -11.142 45.427  1   35.39  ? 291 VAL D CB  1 
ATOM   983  C CG1 . VAL A 1 121 ? -28.907 -10.768 45      1   35.7   ? 291 VAL D CG1 1 
ATOM   984  C CG2 . VAL A 1 121 ? -27.431 -12.431 46.254  1   34.39  ? 291 VAL D CG2 1 
ATOM   985  N N   . LEU A 1 122 ? -25.887 -8.898  43.866  1   36.77  ? 292 LEU D N   1 
ATOM   986  C CA  . LEU A 1 122 ? -25.905 -7.58   43.179  1   35.71  ? 292 LEU D CA  1 
ATOM   987  C C   . LEU A 1 122 ? -25.08  -7.669  41.888  1   34.94  ? 292 LEU D C   1 
ATOM   988  O O   . LEU A 1 122 ? -25.535 -7.131  40.856  1   36.16  ? 292 LEU D O   1 
ATOM   989  C CB  . LEU A 1 122 ? -25.369 -6.506  44.123  1   35.4   ? 292 LEU D CB  1 
ATOM   990  C CG  . LEU A 1 122 ? -26.363 -5.996  45.171  1   34.23  ? 292 LEU D CG  1 
ATOM   991  C CD1 . LEU A 1 122 ? -25.865 -4.72   45.82   1   36.28  ? 292 LEU D CD1 1 
ATOM   992  C CD2 . LEU A 1 122 ? -27.727 -5.782  44.538  1   30.72  ? 292 LEU D CD2 1 
ATOM   993  N N   . ARG A 1 123 ? -23.918 -8.296  41.902  1   33.27  ? 293 ARG D N   1 
ATOM   994  C CA  . ARG A 1 123 ? -23.151 -8.417  40.644  1   33.09  ? 293 ARG D CA  1 
ATOM   995  C C   . ARG A 1 123 ? -23.973 -9.215  39.625  1   32.56  ? 293 ARG D C   1 
ATOM   996  O O   . ARG A 1 123 ? -23.969 -8.816  38.452  1   32.7   ? 293 ARG D O   1 
ATOM   997  C CB  . ARG A 1 123 ? -21.766 -8.987  40.957  1   36.38  ? 293 ARG D CB  1 
ATOM   998  C CG  . ARG A 1 123 ? -20.702 -7.941  41.246  1   40.8   ? 293 ARG D CG  1 
ATOM   999  C CD  . ARG A 1 123 ? -19.403 -8.589  41.686  1   49.82  ? 293 ARG D CD  1 
ATOM   1000 N NE  . ARG A 1 123 ? -18.801 -9.409  40.631  1   59.54  ? 293 ARG D NE  1 
ATOM   1001 C CZ  . ARG A 1 123 ? -18.349 -10.647 40.791  1   60.36  ? 293 ARG D CZ  1 
ATOM   1002 N NH1 . ARG A 1 123 ? -18.483 -11.266 41.95   1   52.08  ? 293 ARG D NH1 1 
ATOM   1003 N NH2 . ARG A 1 123 ? -17.769 -11.263 39.781  1   60.4   ? 293 ARG D NH2 1 
ATOM   1004 N N   . MET A 1 124 ? -24.673 -10.267 40.033  1   30.48  ? 294 MET D N   1 
ATOM   1005 C CA  . MET A 1 124 ? -25.542 -10.997 39.076  1   28.96  ? 294 MET D CA  1 
ATOM   1006 C C   . MET A 1 124 ? -26.632 -10.06  38.548  1   29.95  ? 294 MET D C   1 
ATOM   1007 O O   . MET A 1 124 ? -26.907 -10.093 37.351  1   31.79  ? 294 MET D O   1 
ATOM   1008 C CB  . MET A 1 124 ? -26.172 -12.231 39.724  1   26.73  ? 294 MET D CB  1 
ATOM   1009 C CG  . MET A 1 124 ? -26.853 -13.175 38.76   1   25.1   ? 294 MET D CG  1 
ATOM   1010 S SD  . MET A 1 124 ? -25.866 -13.633 37.328  1   26.83  ? 294 MET D SD  1 
ATOM   1011 C CE  . MET A 1 124 ? -25.352 -15.262 37.873  1   26.39  ? 294 MET D CE  1 
ATOM   1012 N N   . GLU A 1 125 ? -27.208 -9.236  39.409  1   29.89  ? 295 GLU D N   1 
ATOM   1013 C CA  . GLU A 1 125 ? -28.197 -8.284  38.941  1   30.82  ? 295 GLU D CA  1 
ATOM   1014 C C   . GLU A 1 125 ? -27.679 -7.489  37.733  1   32.03  ? 295 GLU D C   1 
ATOM   1015 O O   . GLU A 1 125 ? -28.38  -7.387  36.737  1   30.62  ? 295 GLU D O   1 
ATOM   1016 C CB  . GLU A 1 125 ? -28.687 -7.385  40.072  1   30.55  ? 295 GLU D CB  1 
ATOM   1017 C CG  . GLU A 1 125 ? -29.87  -6.537  39.635  1   31.16  ? 295 GLU D CG  1 
ATOM   1018 C CD  . GLU A 1 125 ? -30.318 -5.484  40.617  1   34.97  ? 295 GLU D CD  1 
ATOM   1019 O OE1 . GLU A 1 125 ? -29.487 -4.633  41.013  1   37.46  ? 295 GLU D OE1 1 
ATOM   1020 O OE2 . GLU A 1 125 ? -31.511 -5.506  40.972  1   37.4   ? 295 GLU D OE2 1 
ATOM   1021 N N   . HIS A 1 126 ? -26.465 -6.915  37.804  1   34.93  ? 296 HIS D N   1 
ATOM   1022 C CA  . HIS A 1 126 ? -26.016 -6.055  36.717  1   38.27  ? 296 HIS D CA  1 
ATOM   1023 C C   . HIS A 1 126 ? -25.789 -6.904  35.468  1   37.59  ? 296 HIS D C   1 
ATOM   1024 O O   . HIS A 1 126 ? -26.02  -6.434  34.344  1   36.09  ? 296 HIS D O   1 
ATOM   1025 C CB  . HIS A 1 126 ? -24.786 -5.2    37.07   1   42.04  ? 296 HIS D CB  1 
ATOM   1026 C CG  . HIS A 1 126 ? -24.681 -3.946  36.252  1   51.11  ? 296 HIS D CG  1 
ATOM   1027 N ND1 . HIS A 1 126 ? -23.528 -3.238  35.996  1   55.62  ? 296 HIS D ND1 1 
ATOM   1028 C CD2 . HIS A 1 126 ? -25.68  -3.234  35.642  1   58.82  ? 296 HIS D CD2 1 
ATOM   1029 C CE1 . HIS A 1 126 ? -23.838 -2.158  35.259  1   61.93  ? 296 HIS D CE1 1 
ATOM   1030 N NE2 . HIS A 1 126 ? -25.151 -2.111  35.051  1   52.09  ? 296 HIS D NE2 1 
ATOM   1031 N N   . LEU A 1 127 ? -25.315 -8.144  35.688  1   35.04  ? 297 LEU D N   1 
ATOM   1032 C CA  . LEU A 1 127 ? -25.023 -9.056  34.595  1   31.77  ? 297 LEU D CA  1 
ATOM   1033 C C   . LEU A 1 127 ? -26.322 -9.402  33.876  1   31.35  ? 297 LEU D C   1 
ATOM   1034 O O   . LEU A 1 127 ? -26.331 -9.534  32.642  1   31.4   ? 297 LEU D O   1 
ATOM   1035 C CB  . LEU A 1 127 ? -24.313 -10.323 35.064  1   28.79  ? 297 LEU D CB  1 
ATOM   1036 C CG  . LEU A 1 127 ? -23.98  -11.32  33.948  1   26.73  ? 297 LEU D CG  1 
ATOM   1037 C CD1 . LEU A 1 127 ? -23.034 -10.704 32.938  1   26.22  ? 297 LEU D CD1 1 
ATOM   1038 C CD2 . LEU A 1 127 ? -23.425 -12.624 34.494  1   26.39  ? 297 LEU D CD2 1 
ATOM   1039 N N   . VAL A 1 128 ? -27.397 -9.565  34.662  1   28.54  ? 298 VAL D N   1 
ATOM   1040 C CA  . VAL A 1 128 ? -28.645 -10.009 34.073  1   27.68  ? 298 VAL D CA  1 
ATOM   1041 C C   . VAL A 1 128 ? -29.203 -8.903  33.185  1   28.71  ? 298 VAL D C   1 
ATOM   1042 O O   . VAL A 1 128 ? -29.685 -9.174  32.081  1   29.76  ? 298 VAL D O   1 
ATOM   1043 C CB  . VAL A 1 128 ? -29.676 -10.5   35.093  1   26.7   ? 298 VAL D CB  1 
ATOM   1044 C CG1 . VAL A 1 128 ? -30.985 -10.872 34.397  1   25.16  ? 298 VAL D CG1 1 
ATOM   1045 C CG2 . VAL A 1 128 ? -29.13  -11.672 35.894  1   26.5   ? 298 VAL D CG2 1 
ATOM   1046 N N   . LEU A 1 129 ? -29.133 -7.669  33.693  1   28.94  ? 299 LEU D N   1 
ATOM   1047 C CA  . LEU A 1 129 ? -29.554 -6.5    32.939  1   28.37  ? 299 LEU D CA  1 
ATOM   1048 C C   . LEU A 1 129 ? -28.748 -6.419  31.645  1   28.74  ? 299 LEU D C   1 
ATOM   1049 O O   . LEU A 1 129 ? -29.321 -6.198  30.588  1   27.41  ? 299 LEU D O   1 
ATOM   1050 C CB  . LEU A 1 129 ? -29.454 -5.223  33.777  1   28.33  ? 299 LEU D CB  1 
ATOM   1051 C CG  . LEU A 1 129 ? -30.467 -5.083  34.92   1   27.88  ? 299 LEU D CG  1 
ATOM   1052 C CD1 . LEU A 1 129 ? -30.045 -4.026  35.908  1   26.41  ? 299 LEU D CD1 1 
ATOM   1053 C CD2 . LEU A 1 129 ? -31.837 -4.77   34.38   1   28.05  ? 299 LEU D CD2 1 
ATOM   1054 N N   . LYS A 1 130 ? -27.426 -6.597  31.746  1   31.63  ? 300 LYS D N   1 
ATOM   1055 C CA  . LYS A 1 130 ? -26.558 -6.524  30.581  1   36.07  ? 300 LYS D CA  1 
ATOM   1056 C C   . LYS A 1 130 ? -26.987 -7.569  29.545  1   34.49  ? 300 LYS D C   1 
ATOM   1057 O O   . LYS A 1 130 ? -27.138 -7.247  28.37   1   37.08  ? 300 LYS D O   1 
ATOM   1058 C CB  . LYS A 1 130 ? -25.06  -6.671  30.888  1   44.01  ? 300 LYS D CB  1 
ATOM   1059 C CG  . LYS A 1 130 ? -24.379 -5.554  31.694  1   54.03  ? 300 LYS D CG  1 
ATOM   1060 C CD  . LYS A 1 130 ? -22.89  -5.744  32.002  1   64.81  ? 300 LYS D CD  1 
ATOM   1061 C CE  . LYS A 1 130 ? -22.241 -4.612  32.779  1   67.67  ? 300 LYS D CE  1 
ATOM   1062 N NZ  . LYS A 1 130 ? -20.825 -4.812  33.089  1   64.91  ? 300 LYS D NZ  1 
ATOM   1063 N N   . VAL A 1 131 ? -27.216 -8.809  29.983  1   29.47  ? 301 VAL D N   1 
ATOM   1064 C CA  . VAL A 1 131 ? -27.498 -9.882  29.05   1   28.12  ? 301 VAL D CA  1 
ATOM   1065 C C   . VAL A 1 131 ? -28.865 -9.69   28.4    1   27.89  ? 301 VAL D C   1 
ATOM   1066 O O   . VAL A 1 131 ? -28.999 -9.933  27.21   1   28.05  ? 301 VAL D O   1 
ATOM   1067 C CB  . VAL A 1 131 ? -27.387 -11.259 29.723  1   27.95  ? 301 VAL D CB  1 
ATOM   1068 C CG1 . VAL A 1 131 ? -28.137 -12.338 28.952  1   26.98  ? 301 VAL D CG1 1 
ATOM   1069 C CG2 . VAL A 1 131 ? -25.934 -11.66  29.905  1   29.25  ? 301 VAL D CG2 1 
ATOM   1070 N N   . LEU A 1 132 ? -29.876 -9.307  29.192  1   28.6   ? 302 LEU D N   1 
ATOM   1071 C CA  . LEU A 1 132 ? -31.224 -9.017  28.711  1   29.01  ? 302 LEU D CA  1 
ATOM   1072 C C   . LEU A 1 132 ? -31.316 -7.626  28.079  1   30.93  ? 302 LEU D C   1 
ATOM   1073 O O   . LEU A 1 132 ? -32.377 -7.265  27.578  1   32.12  ? 302 LEU D O   1 
ATOM   1074 C CB  . LEU A 1 132 ? -32.214 -9.094  29.873  1   27.11  ? 302 LEU D CB  1 
ATOM   1075 C CG  . LEU A 1 132 ? -32.344 -10.453 30.556  1   27.28  ? 302 LEU D CG  1 
ATOM   1076 C CD1 . LEU A 1 132 ? -33.412 -10.398 31.638  1   26.79  ? 302 LEU D CD1 1 
ATOM   1077 C CD2 . LEU A 1 132 ? -32.636 -11.571 29.548  1   25.57  ? 302 LEU D CD2 1 
ATOM   1078 N N   . ALA A 1 133 ? -30.237 -6.835  28.169  1   31.85  ? 303 ALA D N   1 
ATOM   1079 C CA  . ALA A 1 133 ? -30.199 -5.466  27.675  1   32.49  ? 303 ALA D CA  1 
ATOM   1080 C C   . ALA A 1 133 ? -31.416 -4.672  28.156  1   33.09  ? 303 ALA D C   1 
ATOM   1081 O O   . ALA A 1 133 ? -32.041 -3.962  27.369  1   32.41  ? 303 ALA D O   1 
ATOM   1082 C CB  . ALA A 1 133 ? -30.074 -5.457  26.168  1   32.67  ? 303 ALA D CB  1 
ATOM   1083 N N   . PHE A 1 134 ? -31.764 -4.832  29.441  1   34.05  ? 304 PHE D N   1 
ATOM   1084 C CA  . PHE A 1 134 ? -32.762 -4.008  30.118  1   37.48  ? 304 PHE D CA  1 
ATOM   1085 C C   . PHE A 1 134 ? -34.193 -4.225  29.614  1   40.07  ? 304 PHE D C   1 
ATOM   1086 O O   . PHE A 1 134 ? -35.104 -3.542  30.097  1   38.78  ? 304 PHE D O   1 
ATOM   1087 C CB  . PHE A 1 134 ? -32.429 -2.517  30.079  1   38.3   ? 304 PHE D CB  1 
ATOM   1088 C CG  . PHE A 1 134 ? -31.495 -2.068  31.19   1   40.24  ? 304 PHE D CG  1 
ATOM   1089 C CD1 . PHE A 1 134 ? -30.115 -2.079  31.003  1   41.91  ? 304 PHE D CD1 1 
ATOM   1090 C CD2 . PHE A 1 134 ? -32.012 -1.618  32.408  1   39.87  ? 304 PHE D CD2 1 
ATOM   1091 C CE1 . PHE A 1 134 ? -29.272 -1.648  32.02   1   44.98  ? 304 PHE D CE1 1 
ATOM   1092 C CE2 . PHE A 1 134 ? -31.166 -1.19   33.419  1   41.78  ? 304 PHE D CE2 1 
ATOM   1093 C CZ  . PHE A 1 134 ? -29.798 -1.197  33.221  1   44.61  ? 304 PHE D CZ  1 
ATOM   1094 N N   . ASP A 1 135 ? -34.384 -5.182  28.684  1   41.17  ? 305 ASP D N   1 
ATOM   1095 C CA  . ASP A 1 135 ? -35.695 -5.52   28.137  1   45.57  ? 305 ASP D CA  1 
ATOM   1096 C C   . ASP A 1 135 ? -36.497 -6.353  29.143  1   42.11  ? 305 ASP D C   1 
ATOM   1097 O O   . ASP A 1 135 ? -36.541 -7.583  29.057  1   42.01  ? 305 ASP D O   1 
ATOM   1098 C CB  . ASP A 1 135 ? -35.578 -6.211  26.79   1   52.58  ? 305 ASP D CB  1 
ATOM   1099 C CG  . ASP A 1 135 ? -35.195 -5.287  25.651  1   64.5   ? 305 ASP D CG  1 
ATOM   1100 O OD1 . ASP A 1 135 ? -33.988 -5.061  25.434  1   65.81  ? 305 ASP D OD1 1 
ATOM   1101 O OD2 . ASP A 1 135 ? -36.126 -4.769  25.021  1   84.38  ? 305 ASP D OD2 1 
ATOM   1102 N N   . LEU A 1 136 ? -37.126 -5.677  30.111  1   35.59  ? 306 LEU D N   1 
ATOM   1103 C CA  . LEU A 1 136 ? -37.674 -6.389  31.25   1   32.7   ? 306 LEU D CA  1 
ATOM   1104 C C   . LEU A 1 136 ? -39.199 -6.471  31.16   1   31.8   ? 306 LEU D C   1 
ATOM   1105 O O   . LEU A 1 136 ? -39.827 -7.24   31.879  1   29.19  ? 306 LEU D O   1 
ATOM   1106 C CB  . LEU A 1 136 ? -37.202 -5.704  32.535  1   34.28  ? 306 LEU D CB  1 
ATOM   1107 C CG  . LEU A 1 136 ? -35.706 -5.759  32.887  1   35.26  ? 306 LEU D CG  1 
ATOM   1108 C CD1 . LEU A 1 136 ? -35.541 -5.928  34.395  1   34.91  ? 306 LEU D CD1 1 
ATOM   1109 C CD2 . LEU A 1 136 ? -34.894 -6.835  32.174  1   33.86  ? 306 LEU D CD2 1 
ATOM   1110 N N   . ALA A 1 137 ? -39.798 -5.668  30.274  1   33.05  ? 307 ALA D N   1 
ATOM   1111 C CA  . ALA A 1 137 ? -41.246 -5.529  30.211  1   34.69  ? 307 ALA D CA  1 
ATOM   1112 C C   . ALA A 1 137 ? -41.813 -6.657  29.362  1   35.82  ? 307 ALA D C   1 
ATOM   1113 O O   . ALA A 1 137 ? -42.4   -6.426  28.297  1   36.69  ? 307 ALA D O   1 
ATOM   1114 C CB  . ALA A 1 137 ? -41.607 -4.18   29.632  1   36.43  ? 307 ALA D CB  1 
ATOM   1115 N N   . ALA A 1 138 ? -41.567 -7.879  29.833  1   35.13  ? 308 ALA D N   1 
ATOM   1116 C CA  . ALA A 1 138 ? -41.879 -9.058  29.049  1   36.77  ? 308 ALA D CA  1 
ATOM   1117 C C   . ALA A 1 138 ? -43.336 -9.413  29.304  1   40.04  ? 308 ALA D C   1 
ATOM   1118 O O   . ALA A 1 138 ? -43.772 -9.44   30.457  1   42.38  ? 308 ALA D O   1 
ATOM   1119 C CB  . ALA A 1 138 ? -40.953 -10.201 29.399  1   32.54  ? 308 ALA D CB  1 
ATOM   1120 N N   . PRO A 1 139 ? -44.141 -9.673  28.246  1   39.19  ? 309 PRO D N   1 
ATOM   1121 C CA  . PRO A 1 139 ? -45.512 -10.133 28.449  1   39.42  ? 309 PRO D CA  1 
ATOM   1122 C C   . PRO A 1 139 ? -45.477 -11.553 29.024  1   38.62  ? 309 PRO D C   1 
ATOM   1123 O O   . PRO A 1 139 ? -44.566 -12.339 28.755  1   36.34  ? 309 PRO D O   1 
ATOM   1124 C CB  . PRO A 1 139 ? -46.175 -10.045 27.064  1   39.49  ? 309 PRO D CB  1 
ATOM   1125 C CG  . PRO A 1 139 ? -45.122 -9.471  26.134  1   38.36  ? 309 PRO D CG  1 
ATOM   1126 C CD  . PRO A 1 139 ? -43.779 -9.548  26.827  1   37.35  ? 309 PRO D CD  1 
ATOM   1127 N N   . THR A 1 140 ? -46.505 -11.861 29.821  1   39.2   ? 310 THR D N   1 
ATOM   1128 C CA  . THR A 1 140 ? -46.569 -13.08  30.607  1   39.05  ? 310 THR D CA  1 
ATOM   1129 C C   . THR A 1 140 ? -47.88  -13.785 30.286  1   42.78  ? 310 THR D C   1 
ATOM   1130 O O   . THR A 1 140 ? -48.705 -13.252 29.532  1   43.31  ? 310 THR D O   1 
ATOM   1131 C CB  . THR A 1 140 ? -46.51  -12.701 32.087  1   38.16  ? 310 THR D CB  1 
ATOM   1132 O OG1 . THR A 1 140 ? -47.47  -11.676 32.347  1   38.64  ? 310 THR D OG1 1 
ATOM   1133 C CG2 . THR A 1 140 ? -45.136 -12.219 32.501  1   34.94  ? 310 THR D CG2 1 
ATOM   1134 N N   . ILE A 1 141 ? -48.052 -14.985 30.863  1   44.62  ? 311 ILE D N   1 
ATOM   1135 C CA  . ILE A 1 141 ? -49.321 -15.693 30.785  1   46.7   ? 311 ILE D CA  1 
ATOM   1136 C C   . ILE A 1 141 ? -50.354 -14.855 31.53   1   47.78  ? 311 ILE D C   1 
ATOM   1137 O O   . ILE A 1 141 ? -51.35  -14.436 30.949  1   47.57  ? 311 ILE D O   1 
ATOM   1138 C CB  . ILE A 1 141 ? -49.203 -17.119 31.352  1   45.39  ? 311 ILE D CB  1 
ATOM   1139 C CG1 . ILE A 1 141 ? -48.43  -18.017 30.402  1   49.01  ? 311 ILE D CG1 1 
ATOM   1140 C CG2 . ILE A 1 141 ? -50.568 -17.707 31.711  1   45.18  ? 311 ILE D CG2 1 
ATOM   1141 C CD1 . ILE A 1 141 ? -47.607 -19.068 31.125  1   50.51  ? 311 ILE D CD1 1 
ATOM   1142 N N   . ASN A 1 142 ? -50.088 -14.608 32.81   1   47.01  ? 312 ASN D N   1 
ATOM   1143 C CA  . ASN A 1 142 ? -51.032 -13.855 33.67   1   50.12  ? 312 ASN D CA  1 
ATOM   1144 C C   . ASN A 1 142 ? -51.558 -12.613 32.96   1   50.16  ? 312 ASN D C   1 
ATOM   1145 O O   . ASN A 1 142 ? -52.706 -12.24  33.221  1   52.7   ? 312 ASN D O   1 
ATOM   1146 C CB  . ASN A 1 142 ? -50.347 -13.437 34.962  1   54.85  ? 312 ASN D CB  1 
ATOM   1147 C CG  . ASN A 1 142 ? -50.611 -14.383 36.102  1   64.93  ? 312 ASN D CG  1 
ATOM   1148 O OD1 . ASN A 1 142 ? -50.589 -15.603 35.918  1   75.51  ? 312 ASN D OD1 1 
ATOM   1149 N ND2 . ASN A 1 142 ? -50.857 -13.836 37.28   1   68.41  ? 312 ASN D ND2 1 
ATOM   1150 N N   . GLN A 1 143 ? -50.75  -11.993 32.109  1   44.27  ? 313 GLN D N   1 
ATOM   1151 C CA  . GLN A 1 143 ? -51.152 -10.74  31.487  1   42.66  ? 313 GLN D CA  1 
ATOM   1152 C C   . GLN A 1 143 ? -52.215 -10.942 30.417  1   45.22  ? 313 GLN D C   1 
ATOM   1153 O O   . GLN A 1 143 ? -53.089 -10.097 30.266  1   51.05  ? 313 GLN D O   1 
ATOM   1154 C CB  . GLN A 1 143 ? -49.976 -10.051 30.807  1   40.66  ? 313 GLN D CB  1 
ATOM   1155 C CG  . GLN A 1 143 ? -49.253 -9.069  31.716  1   39.04  ? 313 GLN D CG  1 
ATOM   1156 C CD  . GLN A 1 143 ? -48.038 -8.49   31.043  1   37.18  ? 313 GLN D CD  1 
ATOM   1157 O OE1 . GLN A 1 143 ? -48.158 -7.665  30.131  1   38.16  ? 313 GLN D OE1 1 
ATOM   1158 N NE2 . GLN A 1 143 ? -46.876 -8.949  31.482  1   33.93  ? 313 GLN D NE2 1 
ATOM   1159 N N   . PHE A 1 144 ? -52.087 -12.015 29.636  1   44.62  ? 314 PHE D N   1 
ATOM   1160 C CA  . PHE A 1 144 ? -53.108 -12.4   28.68   1   45.1   ? 314 PHE D CA  1 
ATOM   1161 C C   . PHE A 1 144 ? -54.346 -12.869 29.438  1   47.59  ? 314 PHE D C   1 
ATOM   1162 O O   . PHE A 1 144 ? -55.448 -12.386 29.18   1   52.18  ? 314 PHE D O   1 
ATOM   1163 C CB  . PHE A 1 144 ? -52.578 -13.432 27.682  1   42.02  ? 314 PHE D CB  1 
ATOM   1164 C CG  . PHE A 1 144 ? -51.586 -12.861 26.683  1   39.44  ? 314 PHE D CG  1 
ATOM   1165 C CD1 . PHE A 1 144 ? -52.015 -12.1   25.595  1   40.05  ? 314 PHE D CD1 1 
ATOM   1166 C CD2 . PHE A 1 144 ? -50.234 -13.111 26.814  1   37.27  ? 314 PHE D CD2 1 
ATOM   1167 C CE1 . PHE A 1 144 ? -51.113 -11.585 24.675  1   37.89  ? 314 PHE D CE1 1 
ATOM   1168 C CE2 . PHE A 1 144 ? -49.341 -12.595 25.891  1   36.88  ? 314 PHE D CE2 1 
ATOM   1169 C CZ  . PHE A 1 144 ? -49.783 -11.847 24.818  1   36.64  ? 314 PHE D CZ  1 
ATOM   1170 N N   . LEU A 1 145 ? -54.137 -13.779 30.391  1   45.66  ? 315 LEU D N   1 
ATOM   1171 C CA  . LEU A 1 145 ? -55.195 -14.352 31.208  1   48.15  ? 315 LEU D CA  1 
ATOM   1172 C C   . LEU A 1 145 ? -56.175 -13.282 31.691  1   51.09  ? 315 LEU D C   1 
ATOM   1173 O O   . LEU A 1 145 ? -57.382 -13.425 31.502  1   56.42  ? 315 LEU D O   1 
ATOM   1174 C CB  . LEU A 1 145 ? -54.572 -15.082 32.401  1   45.68  ? 315 LEU D CB  1 
ATOM   1175 C CG  . LEU A 1 145 ? -54.307 -16.577 32.222  1   45.93  ? 315 LEU D CG  1 
ATOM   1176 C CD1 . LEU A 1 145 ? -53.896 -17.156 33.57   1   45.52  ? 315 LEU D CD1 1 
ATOM   1177 C CD2 . LEU A 1 145 ? -55.529 -17.302 31.63   1   48.31  ? 315 LEU D CD2 1 
ATOM   1178 N N   . THR A 1 146 ? -55.654 -12.237 32.355  1   49.39  ? 316 THR D N   1 
ATOM   1179 C CA  . THR A 1 146 ? -56.473 -11.217 32.997  1   50.06  ? 316 THR D CA  1 
ATOM   1180 C C   . THR A 1 146 ? -57.397 -10.572 31.966  1   51.33  ? 316 THR D C   1 
ATOM   1181 O O   . THR A 1 146 ? -58.531 -10.22  32.294  1   56.81  ? 316 THR D O   1 
ATOM   1182 C CB  . THR A 1 146 ? -55.627 -10.174 33.736  1   49.02  ? 316 THR D CB  1 
ATOM   1183 O OG1 . THR A 1 146 ? -54.68  -9.663  32.798  1   49.98  ? 316 THR D OG1 1 
ATOM   1184 C CG2 . THR A 1 146 ? -54.961 -10.693 35.002  1   45.5   ? 316 THR D CG2 1 
ATOM   1185 N N   . GLN A 1 147 ? -56.915 -10.44  30.724  1   48.23  ? 317 GLN D N   1 
ATOM   1186 C CA  . GLN A 1 147 ? -57.723 -9.906  29.643  1   49.93  ? 317 GLN D CA  1 
ATOM   1187 C C   . GLN A 1 147 ? -58.79  -10.913 29.236  1   52.08  ? 317 GLN D C   1 
ATOM   1188 O O   . GLN A 1 147 ? -59.941 -10.54  28.997  1   55.03  ? 317 GLN D O   1 
ATOM   1189 C CB  . GLN A 1 147 ? -56.847 -9.612  28.432  1   51.57  ? 317 GLN D CB  1 
ATOM   1190 C CG  . GLN A 1 147 ? -56.021 -8.342  28.572  1   55.48  ? 317 GLN D CG  1 
ATOM   1191 C CD  . GLN A 1 147 ? -55.264 -8.024  27.305  1   58.23  ? 317 GLN D CD  1 
ATOM   1192 O OE1 . GLN A 1 147 ? -54.042 -8.173  27.253  1   61.86  ? 317 GLN D OE1 1 
ATOM   1193 N NE2 . GLN A 1 147 ? -55.985 -7.597  26.28   1   57.27  ? 317 GLN D NE2 1 
ATOM   1194 N N   . TYR A 1 148 ? -58.374 -12.179 29.108  1   51.84  ? 318 TYR D N   1 
ATOM   1195 C CA  . TYR A 1 148 ? -59.274 -13.268 28.757  1   53.37  ? 318 TYR D CA  1 
ATOM   1196 C C   . TYR A 1 148 ? -60.375 -13.334 29.808  1   56.5   ? 318 TYR D C   1 
ATOM   1197 O O   . TYR A 1 148 ? -61.542 -13.535 29.476  1   60.74  ? 318 TYR D O   1 
ATOM   1198 C CB  . TYR A 1 148 ? -58.52  -14.598 28.7    1   52.1   ? 318 TYR D CB  1 
ATOM   1199 C CG  . TYR A 1 148 ? -57.46  -14.736 27.616  1   50.64  ? 318 TYR D CG  1 
ATOM   1200 C CD1 . TYR A 1 148 ? -57.409 -13.87  26.528  1   50.74  ? 318 TYR D CD1 1 
ATOM   1201 C CD2 . TYR A 1 148 ? -56.506 -15.739 27.686  1   49.11  ? 318 TYR D CD2 1 
ATOM   1202 C CE1 . TYR A 1 148 ? -56.439 -13.996 25.549  1   49.6   ? 318 TYR D CE1 1 
ATOM   1203 C CE2 . TYR A 1 148 ? -55.555 -15.894 26.691  1   48.22  ? 318 TYR D CE2 1 
ATOM   1204 C CZ  . TYR A 1 148 ? -55.521 -15.024 25.617  1   48.28  ? 318 TYR D CZ  1 
ATOM   1205 O OH  . TYR A 1 148 ? -54.579 -15.144 24.637  1   46.95  ? 318 TYR D OH  1 
ATOM   1206 N N   . PHE A 1 149 ? -59.993 -13.112 31.072  1   55.49  ? 319 PHE D N   1 
ATOM   1207 C CA  . PHE A 1 149 ? -60.937 -13.112 32.176  1   58.22  ? 319 PHE D CA  1 
ATOM   1208 C C   . PHE A 1 149 ? -62.072 -12.121 31.958  1   60.93  ? 319 PHE D C   1 
ATOM   1209 O O   . PHE A 1 149 ? -63.157 -12.317 32.503  1   63.79  ? 319 PHE D O   1 
ATOM   1210 C CB  . PHE A 1 149 ? -60.273 -12.745 33.496  1   58.82  ? 319 PHE D CB  1 
ATOM   1211 C CG  . PHE A 1 149 ? -59.466 -13.862 34.133  1   61.22  ? 319 PHE D CG  1 
ATOM   1212 C CD1 . PHE A 1 149 ? -59.343 -15.109 33.514  1   60.49  ? 319 PHE D CD1 1 
ATOM   1213 C CD2 . PHE A 1 149 ? -58.828 -13.634 35.352  1   61.25  ? 319 PHE D CD2 1 
ATOM   1214 C CE1 . PHE A 1 149 ? -58.597 -16.105 34.118  1   62.13  ? 319 PHE D CE1 1 
ATOM   1215 C CE2 . PHE A 1 149 ? -58.096 -14.636 35.957  1   63.17  ? 319 PHE D CE2 1 
ATOM   1216 C CZ  . PHE A 1 149 ? -57.986 -15.868 35.335  1   64.82  ? 319 PHE D CZ  1 
ATOM   1217 N N   . LEU A 1 150 ? -61.826 -11.075 31.163  1   61.17  ? 320 LEU D N   1 
ATOM   1218 C CA  . LEU A 1 150 ? -62.81  -10.022 30.961  1   63.57  ? 320 LEU D CA  1 
ATOM   1219 C C   . LEU A 1 150 ? -64.004 -10.523 30.145  1   68     ? 320 LEU D C   1 
ATOM   1220 O O   . LEU A 1 150 ? -65.08  -9.926  30.198  1   71.11  ? 320 LEU D O   1 
ATOM   1221 C CB  . LEU A 1 150 ? -62.145 -8.793  30.339  1   60.55  ? 320 LEU D CB  1 
ATOM   1222 C CG  . LEU A 1 150 ? -61.134 -8.053  31.227  1   56.94  ? 320 LEU D CG  1 
ATOM   1223 C CD1 . LEU A 1 150 ? -60.595 -6.83   30.513  1   56.1   ? 320 LEU D CD1 1 
ATOM   1224 C CD2 . LEU A 1 150 ? -61.687 -7.647  32.595  1   55.49  ? 320 LEU D CD2 1 
ATOM   1225 N N   . HIS A 1 151 ? -63.817 -11.628 29.412  1   68.94  ? 321 HIS D N   1 
ATOM   1226 C CA  . HIS A 1 151 ? -64.842 -12.132 28.509  1   74.8   ? 321 HIS D CA  1 
ATOM   1227 C C   . HIS A 1 151 ? -65.747 -13.156 29.196  1   78.67  ? 321 HIS D C   1 
ATOM   1228 O O   . HIS A 1 151 ? -66.652 -13.709 28.577  1   85.34  ? 321 HIS D O   1 
ATOM   1229 C CB  . HIS A 1 151 ? -64.222 -12.722 27.24   1   75.52  ? 321 HIS D CB  1 
ATOM   1230 C CG  . HIS A 1 151 ? -63.591 -11.709 26.354  1   77.57  ? 321 HIS D CG  1 
ATOM   1231 N ND1 . HIS A 1 151 ? -63.796 -11.683 24.993  1   81.37  ? 321 HIS D ND1 1 
ATOM   1232 C CD2 . HIS A 1 151 ? -62.766 -10.687 26.626  1   78.86  ? 321 HIS D CD2 1 
ATOM   1233 C CE1 . HIS A 1 151 ? -63.108 -10.678 24.464  1   81.08  ? 321 HIS D CE1 1 
ATOM   1234 N NE2 . HIS A 1 151 ? -62.484 -10.054 25.44   1   80.21  ? 321 HIS D NE2 1 
ATOM   1235 N N   . GLN A 1 152 ? -65.521 -13.408 30.485  1   76.28  ? 322 GLN D N   1 
ATOM   1236 C CA  . GLN A 1 152 ? -66.377 -14.322 31.217  1   76.66  ? 322 GLN D CA  1 
ATOM   1237 C C   . GLN A 1 152 ? -67.815 -13.824 31.213  1   79.42  ? 322 GLN D C   1 
ATOM   1238 O O   . GLN A 1 152 ? -68.083 -12.647 30.995  1   79.6   ? 322 GLN D O   1 
ATOM   1239 C CB  . GLN A 1 152 ? -65.902 -14.444 32.658  1   77.03  ? 322 GLN D CB  1 
ATOM   1240 C CG  . GLN A 1 152 ? -64.75  -15.42  32.847  1   75.02  ? 322 GLN D CG  1 
ATOM   1241 C CD  . GLN A 1 152 ? -64.601 -15.79  34.299  1   74.09  ? 322 GLN D CD  1 
ATOM   1242 O OE1 . GLN A 1 152 ? -64.976 -16.891 34.704  1   77.28  ? 322 GLN D OE1 1 
ATOM   1243 N NE2 . GLN A 1 152 ? -64.108 -14.85  35.091  1   71.47  ? 322 GLN D NE2 1 
ATOM   1244 N N   . GLN A 1 153 ? -68.732 -14.749 31.489  1   82.99  ? 323 GLN D N   1 
ATOM   1245 C CA  . GLN A 1 153 ? -70.144 -14.425 31.53   1   87.7   ? 323 GLN D CA  1 
ATOM   1246 C C   . GLN A 1 153 ? -70.888 -15.473 32.363  1   91.31  ? 323 GLN D C   1 
ATOM   1247 O O   . GLN A 1 153 ? -71.288 -16.52  31.838  1   93.11  ? 323 GLN D O   1 
ATOM   1248 C CB  . GLN A 1 153 ? -70.608 -14.27  30.078  1   88.83  ? 323 GLN D CB  1 
ATOM   1249 C CG  . GLN A 1 153 ? -72.1   -13.979 29.91   1   93.92  ? 323 GLN D CG  1 
ATOM   1250 C CD  . GLN A 1 153 ? -72.593 -12.85  30.786  1   92.68  ? 323 GLN D CD  1 
ATOM   1251 O OE1 . GLN A 1 153 ? -72.054 -11.739 30.77   1   90.01  ? 323 GLN D OE1 1 
ATOM   1252 N NE2 . GLN A 1 153 ? -73.607 -13.147 31.583  1   94.65  ? 323 GLN D NE2 1 
ATOM   1253 N N   . PRO A 1 154 ? -71.084 -15.257 33.692  1   91.88  ? 324 PRO D N   1 
ATOM   1254 C CA  . PRO A 1 154 ? -70.396 -14.217 34.474  1   91.13  ? 324 PRO D CA  1 
ATOM   1255 C C   . PRO A 1 154 ? -69.016 -14.667 34.972  1   91.78  ? 324 PRO D C   1 
ATOM   1256 O O   . PRO A 1 154 ? -68.502 -15.672 34.494  1   97.2   ? 324 PRO D O   1 
ATOM   1257 C CB  . PRO A 1 154 ? -71.388 -13.993 35.619  1   92.58  ? 324 PRO D CB  1 
ATOM   1258 C CG  . PRO A 1 154 ? -71.941 -15.373 35.879  1   94.46  ? 324 PRO D CG  1 
ATOM   1259 C CD  . PRO A 1 154 ? -72.031 -16.032 34.513  1   94.91  ? 324 PRO D CD  1 
ATOM   1260 N N   . ALA A 1 155 ? -68.403 -13.938 35.924  1   86.07  ? 325 ALA D N   1 
ATOM   1261 C CA  . ALA A 1 155 ? -67.068 -14.281 36.406  1   77.32  ? 325 ALA D CA  1 
ATOM   1262 C C   . ALA A 1 155 ? -67.151 -15.418 37.427  1   79.63  ? 325 ALA D C   1 
ATOM   1263 O O   . ALA A 1 155 ? -68.193 -15.585 38.055  1   83.1   ? 325 ALA D O   1 
ATOM   1264 C CB  . ALA A 1 155 ? -66.412 -13.059 36.985  1   71.94  ? 325 ALA D CB  1 
ATOM   1265 N N   . ASN A 1 156 ? -66.074 -16.202 37.526  1   78.45  ? 326 ASN D N   1 
ATOM   1266 C CA  . ASN A 1 156 ? -66.045 -17.352 38.467  1   80.78  ? 326 ASN D CA  1 
ATOM   1267 C C   . ASN A 1 156 ? -64.687 -17.427 39.158  1   80.29  ? 326 ASN D C   1 
ATOM   1268 O O   . ASN A 1 156 ? -63.748 -17.94  38.54   1   81.69  ? 326 ASN D O   1 
ATOM   1269 C CB  . ASN A 1 156 ? -66.338 -18.676 37.776  1   82.29  ? 326 ASN D CB  1 
ATOM   1270 C CG  . ASN A 1 156 ? -66.97  -19.676 38.713  1   86.42  ? 326 ASN D CG  1 
ATOM   1271 O OD1 . ASN A 1 156 ? -66.991 -19.468 39.93   1   86.34  ? 326 ASN D OD1 1 
ATOM   1272 N ND2 . ASN A 1 156 ? -67.492 -20.763 38.168  1   90.69  ? 326 ASN D ND2 1 
ATOM   1273 N N   . CYS A 1 157 ? -64.608 -16.965 40.402  1   83.52  ? 327 CYS D N   1 
ATOM   1274 C CA  . CYS A 1 157 ? -63.362 -17.073 41.192  1   82.92  ? 327 CYS D CA  1 
ATOM   1275 C C   . CYS A 1 157 ? -62.685 -18.41  40.914  1   78.28  ? 327 CYS D C   1 
ATOM   1276 O O   . CYS A 1 157 ? -61.481 -18.414 40.629  1   80.82  ? 327 CYS D O   1 
ATOM   1277 C CB  . CYS A 1 157 ? -63.68  -17.128 42.676  1   93.09  ? 327 CYS D CB  1 
ATOM   1278 S SG  . CYS A 1 157 ? -64.304 -15.574 43.366  1   104.17 ? 327 CYS D SG  1 
ATOM   1279 N N   . LYS A 1 158 ? -63.437 -19.498 41.02   1   73.96  ? 328 LYS D N   1 
ATOM   1280 C CA  . LYS A 1 158 ? -62.857 -20.845 40.828  1   71.35  ? 328 LYS D CA  1 
ATOM   1281 C C   . LYS A 1 158 ? -62.122 -20.903 39.485  1   69.23  ? 328 LYS D C   1 
ATOM   1282 O O   . LYS A 1 158 ? -60.963 -21.325 39.486  1   65.57  ? 328 LYS D O   1 
ATOM   1283 C CB  . LYS A 1 158 ? -63.987 -21.867 40.949  1   74.75  ? 328 LYS D CB  1 
ATOM   1284 C CG  . LYS A 1 158 ? -64.602 -21.987 42.331  1   77.26  ? 328 LYS D CG  1 
ATOM   1285 C CD  . LYS A 1 158 ? -65.736 -23     42.385  1   78.24  ? 328 LYS D CD  1 
ATOM   1286 C CE  . LYS A 1 158 ? -66.317 -23.126 43.756  1   78.12  ? 328 LYS D CE  1 
ATOM   1287 N NZ  . LYS A 1 158 ? -67.423 -24.087 43.786  1   79.54  ? 328 LYS D NZ  1 
ATOM   1288 N N   . VAL A 1 159 ? -62.779 -20.516 38.392  1   68.77  ? 329 VAL D N   1 
ATOM   1289 C CA  . VAL A 1 159 ? -62.149 -20.591 37.042  1   64.01  ? 329 VAL D CA  1 
ATOM   1290 C C   . VAL A 1 159 ? -60.901 -19.713 37.081  1   61.45  ? 329 VAL D C   1 
ATOM   1291 O O   . VAL A 1 159 ? -59.854 -20.175 36.631  1   62.91  ? 329 VAL D O   1 
ATOM   1292 C CB  . VAL A 1 159 ? -63.105 -20.142 35.924  1   62.6   ? 329 VAL D CB  1 
ATOM   1293 C CG1 . VAL A 1 159 ? -62.372 -19.797 34.635  1   58.65  ? 329 VAL D CG1 1 
ATOM   1294 C CG2 . VAL A 1 159 ? -64.196 -21.169 35.665  1   65.43  ? 329 VAL D CG2 1 
ATOM   1295 N N   . GLU A 1 160 ? -61.02  -18.513 37.635  1   60.73  ? 330 GLU D N   1 
ATOM   1296 C CA  . GLU A 1 160 ? -59.913 -17.578 37.73   1   57.59  ? 330 GLU D CA  1 
ATOM   1297 C C   . GLU A 1 160 ? -58.758 -18.251 38.454  1   55.34  ? 330 GLU D C   1 
ATOM   1298 O O   . GLU A 1 160 ? -57.734 -18.577 37.851  1   53.63  ? 330 GLU D O   1 
ATOM   1299 C CB  . GLU A 1 160 ? -60.369 -16.311 38.448  1   60.24  ? 330 GLU D CB  1 
ATOM   1300 C CG  . GLU A 1 160 ? -61.61  -15.69  37.81   1   67.74  ? 330 GLU D CG  1 
ATOM   1301 C CD  . GLU A 1 160 ? -61.646 -14.171 37.646  1   70.61  ? 330 GLU D CD  1 
ATOM   1302 O OE1 . GLU A 1 160 ? -61.382 -13.44  38.625  1   70.86  ? 330 GLU D OE1 1 
ATOM   1303 O OE2 . GLU A 1 160 ? -61.979 -13.703 36.532  1   71.2   ? 330 GLU D OE2 1 
ATOM   1304 N N   . SER A 1 161 ? -58.977 -18.523 39.737  1   56.82  ? 331 SER D N   1 
ATOM   1305 C CA  . SER A 1 161 ? -58.01  -19.254 40.537  1   56.92  ? 331 SER D CA  1 
ATOM   1306 C C   . SER A 1 161 ? -57.51  -20.51  39.82   1   57.33  ? 331 SER D C   1 
ATOM   1307 O O   . SER A 1 161 ? -56.32  -20.813 39.921  1   56.62  ? 331 SER D O   1 
ATOM   1308 C CB  . SER A 1 161 ? -58.55  -19.578 41.904  1   59.01  ? 331 SER D CB  1 
ATOM   1309 O OG  . SER A 1 161 ? -59.043 -18.402 42.532  1   60.56  ? 331 SER D OG  1 
ATOM   1310 N N   . LEU A 1 162 ? -58.394 -21.229 39.104  1   58.94  ? 332 LEU D N   1 
ATOM   1311 C CA  . LEU A 1 162 ? -57.985 -22.464 38.446  1   59.73  ? 332 LEU D CA  1 
ATOM   1312 C C   . LEU A 1 162 ? -57.232 -22.192 37.137  1   58.87  ? 332 LEU D C   1 
ATOM   1313 O O   . LEU A 1 162 ? -56.347 -22.96  36.752  1   60.41  ? 332 LEU D O   1 
ATOM   1314 C CB  . LEU A 1 162 ? -59.143 -23.434 38.249  1   62.73  ? 332 LEU D CB  1 
ATOM   1315 C CG  . LEU A 1 162 ? -58.772 -24.772 37.593  1   64.97  ? 332 LEU D CG  1 
ATOM   1316 C CD1 . LEU A 1 162 ? -57.753 -25.559 38.415  1   62.93  ? 332 LEU D CD1 1 
ATOM   1317 C CD2 . LEU A 1 162 ? -59.998 -25.641 37.33   1   68.66  ? 332 LEU D CD2 1 
ATOM   1318 N N   . ALA A 1 163 ? -57.577 -21.112 36.43   1   57.32  ? 333 ALA D N   1 
ATOM   1319 C CA  . ALA A 1 163 ? -56.806 -20.757 35.251  1   55.74  ? 333 ALA D CA  1 
ATOM   1320 C C   . ALA A 1 163 ? -55.411 -20.304 35.681  1   55.73  ? 333 ALA D C   1 
ATOM   1321 O O   . ALA A 1 163 ? -54.429 -20.734 35.081  1   56.2   ? 333 ALA D O   1 
ATOM   1322 C CB  . ALA A 1 163 ? -57.525 -19.731 34.405  1   53.68  ? 333 ALA D CB  1 
ATOM   1323 N N   . MET A 1 164 ? -55.333 -19.462 36.728  1   56.03  ? 334 MET D N   1 
ATOM   1324 C CA  . MET A 1 164 ? -54.056 -19.059 37.305  1   54.13  ? 334 MET D CA  1 
ATOM   1325 C C   . MET A 1 164 ? -53.223 -20.301 37.607  1   53.28  ? 334 MET D C   1 
ATOM   1326 O O   . MET A 1 164 ? -52.142 -20.453 37.039  1   51     ? 334 MET D O   1 
ATOM   1327 C CB  . MET A 1 164 ? -54.221 -18.219 38.578  1   57.39  ? 334 MET D CB  1 
ATOM   1328 C CG  . MET A 1 164 ? -54.702 -16.777 38.334  1   63.54  ? 334 MET D CG  1 
ATOM   1329 S SD  . MET A 1 164 ? -53.552 -15.656 37.499  1   65.53  ? 334 MET D SD  1 
ATOM   1330 C CE  . MET A 1 164 ? -54.378 -14.06  37.501  1   70.79  ? 334 MET D CE  1 
ATOM   1331 N N   . PHE A 1 165 ? -53.766 -21.202 38.446  1   54.28  ? 335 PHE D N   1 
ATOM   1332 C CA  . PHE A 1 165 ? -53.122 -22.452 38.852  1   52.26  ? 335 PHE D CA  1 
ATOM   1333 C C   . PHE A 1 165 ? -52.476 -23.193 37.673  1   50.34  ? 335 PHE D C   1 
ATOM   1334 O O   . PHE A 1 165 ? -51.32  -23.613 37.781  1   49.37  ? 335 PHE D O   1 
ATOM   1335 C CB  . PHE A 1 165 ? -54.088 -23.388 39.58   1   52.93  ? 335 PHE D CB  1 
ATOM   1336 C CG  . PHE A 1 165 ? -53.565 -24.804 39.807  1   55.5   ? 335 PHE D CG  1 
ATOM   1337 C CD1 . PHE A 1 165 ? -52.612 -25.082 40.79   1   56.15  ? 335 PHE D CD1 1 
ATOM   1338 C CD2 . PHE A 1 165 ? -54.026 -25.876 39.043  1   56.71  ? 335 PHE D CD2 1 
ATOM   1339 C CE1 . PHE A 1 165 ? -52.15  -26.382 41.01   1   56.13  ? 335 PHE D CE1 1 
ATOM   1340 C CE2 . PHE A 1 165 ? -53.575 -27.177 39.279  1   56.08  ? 335 PHE D CE2 1 
ATOM   1341 C CZ  . PHE A 1 165 ? -52.638 -27.432 40.258  1   55.22  ? 335 PHE D CZ  1 
ATOM   1342 N N   . LEU A 1 166 ? -53.22  -23.369 36.569  1   47.68  ? 336 LEU D N   1 
ATOM   1343 C CA  . LEU A 1 166 ? -52.745 -24.162 35.442  1   46.54  ? 336 LEU D CA  1 
ATOM   1344 C C   . LEU A 1 166 ? -51.622 -23.449 34.688  1   44.41  ? 336 LEU D C   1 
ATOM   1345 O O   . LEU A 1 166 ? -50.661 -24.077 34.231  1   42.82  ? 336 LEU D O   1 
ATOM   1346 C CB  . LEU A 1 166 ? -53.911 -24.533 34.528  1   46.5   ? 336 LEU D CB  1 
ATOM   1347 C CG  . LEU A 1 166 ? -54.941 -25.464 35.165  1   48.14  ? 336 LEU D CG  1 
ATOM   1348 C CD1 . LEU A 1 166 ? -56.17  -25.58  34.298  1   50.99  ? 336 LEU D CD1 1 
ATOM   1349 C CD2 . LEU A 1 166 ? -54.335 -26.824 35.414  1   48.34  ? 336 LEU D CD2 1 
ATOM   1350 N N   . GLY A 1 167 ? -51.759 -22.129 34.544  1   44.23  ? 337 GLY D N   1 
ATOM   1351 C CA  . GLY A 1 167 ? -50.728 -21.331 33.902  1   43.95  ? 337 GLY D CA  1 
ATOM   1352 C C   . GLY A 1 167 ? -49.39  -21.555 34.601  1   43.64  ? 337 GLY D C   1 
ATOM   1353 O O   . GLY A 1 167 ? -48.378 -21.826 33.959  1   45.96  ? 337 GLY D O   1 
ATOM   1354 N N   . GLU A 1 168 ? -49.443 -21.507 35.937  1   42.72  ? 338 GLU D N   1 
ATOM   1355 C CA  . GLU A 1 168 ? -48.275 -21.571 36.791  1   41.09  ? 338 GLU D CA  1 
ATOM   1356 C C   . GLU A 1 168 ? -47.63  -22.953 36.684  1   42.67  ? 338 GLU D C   1 
ATOM   1357 O O   . GLU A 1 168 ? -46.402 -23.066 36.742  1   43.66  ? 338 GLU D O   1 
ATOM   1358 C CB  . GLU A 1 168 ? -48.741 -21.222 38.202  1   40.94  ? 338 GLU D CB  1 
ATOM   1359 C CG  . GLU A 1 168 ? -47.72  -20.417 38.985  1   40.06  ? 338 GLU D CG  1 
ATOM   1360 C CD  . GLU A 1 168 ? -48.314 -19.771 40.22   1   42.35  ? 338 GLU D CD  1 
ATOM   1361 O OE1 . GLU A 1 168 ? -47.886 -20.271 41.287  1   43.38  ? 338 GLU D OE1 1 
ATOM   1362 O OE2 . GLU A 1 168 ? -49.13  -18.799 40.133  1   41.17  ? 338 GLU D OE2 1 
ATOM   1363 N N   . LEU A 1 169 ? -48.453 -24.005 36.529  1   43.15  ? 339 LEU D N   1 
ATOM   1364 C CA  . LEU A 1 169 ? -47.95  -25.364 36.407  1   42.01  ? 339 LEU D CA  1 
ATOM   1365 C C   . LEU A 1 169 ? -47.007 -25.461 35.215  1   43.13  ? 339 LEU D C   1 
ATOM   1366 O O   . LEU A 1 169 ? -45.981 -26.137 35.303  1   45.31  ? 339 LEU D O   1 
ATOM   1367 C CB  . LEU A 1 169 ? -49.084 -26.377 36.305  1   42.63  ? 339 LEU D CB  1 
ATOM   1368 C CG  . LEU A 1 169 ? -49.782 -26.787 37.609  1   42.18  ? 339 LEU D CG  1 
ATOM   1369 C CD1 . LEU A 1 169 ? -50.669 -27.98  37.322  1   43.38  ? 339 LEU D CD1 1 
ATOM   1370 C CD2 . LEU A 1 169 ? -48.811 -27.134 38.704  1   40.75  ? 339 LEU D CD2 1 
ATOM   1371 N N   . SER A 1 170 ? -47.35  -24.761 34.123  1   44.37  ? 340 SER D N   1 
ATOM   1372 C CA  . SER A 1 170 ? -46.504 -24.663 32.938  1   44.56  ? 340 SER D CA  1 
ATOM   1373 C C   . SER A 1 170 ? -45.08  -24.154 33.25   1   44.88  ? 340 SER D C   1 
ATOM   1374 O O   . SER A 1 170 ? -44.114 -24.635 32.647  1   47.45  ? 340 SER D O   1 
ATOM   1375 C CB  . SER A 1 170 ? -47.173 -23.837 31.872  1   43.93  ? 340 SER D CB  1 
ATOM   1376 O OG  . SER A 1 170 ? -46.785 -22.468 31.954  1   43.76  ? 340 SER D OG  1 
ATOM   1377 N N   . LEU A 1 171 ? -44.929 -23.181 34.17   1   40.75  ? 341 LEU D N   1 
ATOM   1378 C CA  . LEU A 1 171 ? -43.639 -22.54  34.406  1   37.77  ? 341 LEU D CA  1 
ATOM   1379 C C   . LEU A 1 171 ? -42.575 -23.593 34.721  1   38.29  ? 341 LEU D C   1 
ATOM   1380 O O   . LEU A 1 171 ? -41.453 -23.506 34.222  1   37.67  ? 341 LEU D O   1 
ATOM   1381 C CB  . LEU A 1 171 ? -43.712 -21.487 35.514  1   35.88  ? 341 LEU D CB  1 
ATOM   1382 C CG  . LEU A 1 171 ? -44.737 -20.357 35.353  1   36.29  ? 341 LEU D CG  1 
ATOM   1383 C CD1 . LEU A 1 171 ? -44.81  -19.518 36.62   1   36.72  ? 341 LEU D CD1 1 
ATOM   1384 C CD2 . LEU A 1 171 ? -44.418 -19.465 34.18   1   35.83  ? 341 LEU D CD2 1 
ATOM   1385 N N   . ILE A 1 172 ? -42.959 -24.581 35.549  1   38.23  ? 342 ILE D N   1 
ATOM   1386 C CA  . ILE A 1 172 ? -42.095 -25.61  36.113  1   36.89  ? 342 ILE D CA  1 
ATOM   1387 C C   . ILE A 1 172 ? -41.367 -26.422 35.039  1   37.36  ? 342 ILE D C   1 
ATOM   1388 O O   . ILE A 1 172 ? -40.216 -26.803 35.25   1   37.24  ? 342 ILE D O   1 
ATOM   1389 C CB  . ILE A 1 172 ? -42.967 -26.549 36.957  1   38.54  ? 342 ILE D CB  1 
ATOM   1390 C CG1 . ILE A 1 172 ? -43.431 -25.857 38.234  1   39.12  ? 342 ILE D CG1 1 
ATOM   1391 C CG2 . ILE A 1 172 ? -42.278 -27.89  37.222  1   37.59  ? 342 ILE D CG2 1 
ATOM   1392 C CD1 . ILE A 1 172 ? -42.317 -25.535 39.205  1   39.2   ? 342 ILE D CD1 1 
ATOM   1393 N N   . ASP A 1 173 ? -42.072 -26.734 33.936  1   37.2   ? 343 ASP D N   1 
ATOM   1394 C CA  . ASP A 1 173 ? -41.683 -27.79  33.015  1   37.7   ? 343 ASP D CA  1 
ATOM   1395 C C   . ASP A 1 173 ? -41.278 -27.21  31.667  1   37.98  ? 343 ASP D C   1 
ATOM   1396 O O   . ASP A 1 173 ? -42.092 -27.156 30.755  1   39.8   ? 343 ASP D O   1 
ATOM   1397 C CB  . ASP A 1 173 ? -42.798 -28.813 32.867  1   39.74  ? 343 ASP D CB  1 
ATOM   1398 C CG  . ASP A 1 173 ? -43.089 -29.631 34.112  1   41.53  ? 343 ASP D CG  1 
ATOM   1399 O OD1 . ASP A 1 173 ? -42.107 -30.147 34.685  1   40.97  ? 343 ASP D OD1 1 
ATOM   1400 O OD2 . ASP A 1 173 ? -44.286 -29.737 34.492  1   43.11  ? 343 ASP D OD2 1 
ATOM   1401 N N   . ALA A 1 174 ? -40.006 -26.877 31.471  1   38.69  ? 344 ALA D N   1 
ATOM   1402 C CA  . ALA A 1 174 ? -39.509 -26.394 30.158  1   39.65  ? 344 ALA D CA  1 
ATOM   1403 C C   . ALA A 1 174 ? -40.006 -27.274 29.017  1   39.58  ? 344 ALA D C   1 
ATOM   1404 O O   . ALA A 1 174 ? -40.218 -26.74  27.923  1   38.19  ? 344 ALA D O   1 
ATOM   1405 C CB  . ALA A 1 174 ? -38.015 -26.363 30.179  1   40.35  ? 344 ALA D CB  1 
ATOM   1406 N N   . ASP A 1 175 ? -40.127 -28.578 29.252  1   41.23  ? 345 ASP D N   1 
ATOM   1407 C CA  . ASP A 1 175 ? -40.715 -29.495 28.244  1   43.5   ? 345 ASP D CA  1 
ATOM   1408 C C   . ASP A 1 175 ? -42.082 -29.927 28.761  1   44.61  ? 345 ASP D C   1 
ATOM   1409 O O   . ASP A 1 175 ? -42.135 -30.633 29.774  1   45.9   ? 345 ASP D O   1 
ATOM   1410 C CB  . ASP A 1 175 ? -39.829 -30.691 27.962  1   46.07  ? 345 ASP D CB  1 
ATOM   1411 C CG  . ASP A 1 175 ? -40.151 -31.454 26.687  1   49.73  ? 345 ASP D CG  1 
ATOM   1412 O OD1 . ASP A 1 175 ? -40.518 -30.802 25.691  1   50.93  ? 345 ASP D OD1 1 
ATOM   1413 O OD2 . ASP A 1 175 ? -40.03  -32.693 26.704  1   50.66  ? 345 ASP D OD2 1 
ATOM   1414 N N   . PRO A 1 176 ? -43.182 -29.52  28.107  1   44.88  ? 346 PRO D N   1 
ATOM   1415 C CA  . PRO A 1 176 ? -43.07  -28.859 26.816  1   45.15  ? 346 PRO D CA  1 
ATOM   1416 C C   . PRO A 1 176 ? -43.524 -27.43  26.67   1   44.97  ? 346 PRO D C   1 
ATOM   1417 O O   . PRO A 1 176 ? -44.08  -27.123 25.62   1   49.89  ? 346 PRO D O   1 
ATOM   1418 C CB  . PRO A 1 176 ? -44.128 -29.778 26.276  1   44.85  ? 346 PRO D CB  1 
ATOM   1419 C CG  . PRO A 1 176 ? -45.261 -29.635 27.255  1   44.9   ? 346 PRO D CG  1 
ATOM   1420 C CD  . PRO A 1 176 ? -44.53  -29.743 28.564  1   44.47  ? 346 PRO D CD  1 
ATOM   1421 N N   . TYR A 1 177 ? -43.217 -26.55  27.615  1   41.36  ? 347 TYR D N   1 
ATOM   1422 C CA  . TYR A 1 177 ? -43.835 -25.197 27.563  1   43.3   ? 347 TYR D CA  1 
ATOM   1423 C C   . TYR A 1 177 ? -42.927 -24.124 26.975  1   41.15  ? 347 TYR D C   1 
ATOM   1424 O O   . TYR A 1 177 ? -43.401 -23.012 26.722  1   39.94  ? 347 TYR D O   1 
ATOM   1425 C CB  . TYR A 1 177 ? -44.371 -24.973 28.976  1   43.56  ? 347 TYR D CB  1 
ATOM   1426 C CG  . TYR A 1 177 ? -45.463 -25.967 29.329  1   47.26  ? 347 TYR D CG  1 
ATOM   1427 C CD1 . TYR A 1 177 ? -46.627 -26.045 28.576  1   45.84  ? 347 TYR D CD1 1 
ATOM   1428 C CD2 . TYR A 1 177 ? -45.314 -26.841 30.396  1   47.96  ? 347 TYR D CD2 1 
ATOM   1429 C CE1 . TYR A 1 177 ? -47.619 -26.957 28.885  1   46.69  ? 347 TYR D CE1 1 
ATOM   1430 C CE2 . TYR A 1 177 ? -46.3   -27.753 30.72   1   47.08  ? 347 TYR D CE2 1 
ATOM   1431 C CZ  . TYR A 1 177 ? -47.45  -27.811 29.958  1   49.48  ? 347 TYR D CZ  1 
ATOM   1432 O OH  . TYR A 1 177 ? -48.408 -28.715 30.282  1   53.71  ? 347 TYR D OH  1 
ATOM   1433 N N   . LEU A 1 178 ? -41.662 -24.434 26.745  1   40.4   ? 348 LEU D N   1 
ATOM   1434 C CA  . LEU A 1 178 ? -40.866 -23.433 26.062  1   40.15  ? 348 LEU D CA  1 
ATOM   1435 C C   . LEU A 1 178 ? -41.313 -23.261 24.615  1   43.29  ? 348 LEU D C   1 
ATOM   1436 O O   . LEU A 1 178 ? -40.898 -22.323 23.948  1   45.98  ? 348 LEU D O   1 
ATOM   1437 C CB  . LEU A 1 178 ? -39.389 -23.795 26.145  1   40.19  ? 348 LEU D CB  1 
ATOM   1438 C CG  . LEU A 1 178 ? -38.666 -23.367 27.43   1   41.78  ? 348 LEU D CG  1 
ATOM   1439 C CD1 . LEU A 1 178 ? -37.17  -23.645 27.284  1   40.42  ? 348 LEU D CD1 1 
ATOM   1440 C CD2 . LEU A 1 178 ? -38.912 -21.897 27.858  1   40.2   ? 348 LEU D CD2 1 
ATOM   1441 N N   . LYS A 1 179 ? -42.152 -24.166 24.119  1   47.46  ? 349 LYS D N   1 
ATOM   1442 C CA  . LYS A 1 179 ? -42.482 -24.147 22.703  1   52.46  ? 349 LYS D CA  1 
ATOM   1443 C C   . LYS A 1 179 ? -43.878 -23.567 22.487  1   55.47  ? 349 LYS D C   1 
ATOM   1444 O O   . LYS A 1 179 ? -44.38  -23.57  21.368  1   62.22  ? 349 LYS D O   1 
ATOM   1445 C CB  . LYS A 1 179 ? -42.265 -25.528 22.065  1   53.38  ? 349 LYS D CB  1 
ATOM   1446 C CG  . LYS A 1 179 ? -43.171 -26.657 22.528  1   50.14  ? 349 LYS D CG  1 
ATOM   1447 C CD  . LYS A 1 179 ? -42.471 -28.001 22.37   1   50.55  ? 349 LYS D CD  1 
ATOM   1448 C CE  . LYS A 1 179 ? -43.422 -29.16  22.231  1   52.36  ? 349 LYS D CE  1 
ATOM   1449 N NZ  . LYS A 1 179 ? -42.727 -30.451 22.23   1   51.51  ? 349 LYS D NZ  1 
ATOM   1450 N N   . TYR A 1 180 ? -44.495 -23.067 23.557  1   54.06  ? 350 TYR D N   1 
ATOM   1451 C CA  . TYR A 1 180 ? -45.74  -22.333 23.426  1   51.27  ? 350 TYR D CA  1 
ATOM   1452 C C   . TYR A 1 180 ? -45.508 -20.891 23.862  1   48.33  ? 350 TYR D C   1 
ATOM   1453 O O   . TYR A 1 180 ? -44.703 -20.614 24.764  1   44.15  ? 350 TYR D O   1 
ATOM   1454 C CB  . TYR A 1 180 ? -46.843 -23.011 24.246  1   54.45  ? 350 TYR D CB  1 
ATOM   1455 C CG  . TYR A 1 180 ? -47.09  -24.464 23.876  1   58.44  ? 350 TYR D CG  1 
ATOM   1456 C CD1 . TYR A 1 180 ? -47.841 -24.808 22.751  1   59.76  ? 350 TYR D CD1 1 
ATOM   1457 C CD2 . TYR A 1 180 ? -46.556 -25.492 24.649  1   61.1   ? 350 TYR D CD2 1 
ATOM   1458 C CE1 . TYR A 1 180 ? -48.055 -26.135 22.403  1   59.2   ? 350 TYR D CE1 1 
ATOM   1459 C CE2 . TYR A 1 180 ? -46.773 -26.819 24.309  1   60.14  ? 350 TYR D CE2 1 
ATOM   1460 C CZ  . TYR A 1 180 ? -47.52  -27.14  23.19   1   59.15  ? 350 TYR D CZ  1 
ATOM   1461 O OH  . TYR A 1 180 ? -47.7   -28.458 22.902  1   62.14  ? 350 TYR D OH  1 
ATOM   1462 N N   . LEU A 1 181 ? -46.232 -19.99  23.191  1   48.34  ? 351 LEU D N   1 
ATOM   1463 C CA  . LEU A 1 181 ? -46.235 -18.574 23.519  1   44.03  ? 351 LEU D CA  1 
ATOM   1464 C C   . LEU A 1 181 ? -47.099 -18.355 24.749  1   43.37  ? 351 LEU D C   1 
ATOM   1465 O O   . LEU A 1 181 ? -48.068 -19.075 24.99   1   41.06  ? 351 LEU D O   1 
ATOM   1466 C CB  . LEU A 1 181 ? -46.685 -17.727 22.333  1   42.53  ? 351 LEU D CB  1 
ATOM   1467 C CG  . LEU A 1 181 ? -45.64  -17.559 21.225  1   42.24  ? 351 LEU D CG  1 
ATOM   1468 C CD1 . LEU A 1 181 ? -46.217 -16.933 19.991  1   42.95  ? 351 LEU D CD1 1 
ATOM   1469 C CD2 . LEU A 1 181 ? -44.468 -16.734 21.719  1   42.39  ? 351 LEU D CD2 1 
ATOM   1470 N N   . PRO A 1 182 ? -46.721 -17.391 25.608  1   46.51  ? 352 PRO D N   1 
ATOM   1471 C CA  . PRO A 1 182 ? -47.523 -17.086 26.795  1   47.57  ? 352 PRO D CA  1 
ATOM   1472 C C   . PRO A 1 182 ? -49.009 -16.967 26.457  1   48.15  ? 352 PRO D C   1 
ATOM   1473 O O   . PRO A 1 182 ? -49.821 -17.49  27.223  1   51.79  ? 352 PRO D O   1 
ATOM   1474 C CB  . PRO A 1 182 ? -46.886 -15.785 27.329  1   42.58  ? 352 PRO D CB  1 
ATOM   1475 C CG  . PRO A 1 182 ? -45.438 -15.921 26.904  1   40.84  ? 352 PRO D CG  1 
ATOM   1476 C CD  . PRO A 1 182 ? -45.486 -16.587 25.523  1   43.83  ? 352 PRO D CD  1 
ATOM   1477 N N   . SER A 1 183 ? -49.34  -16.309 25.323  1   43.64  ? 353 SER D N   1 
ATOM   1478 C CA  . SER A 1 183 ? -50.72  -16.108 24.896  1   43.52  ? 353 SER D CA  1 
ATOM   1479 C C   . SER A 1 183 ? -51.437 -17.444 24.685  1   45.29  ? 353 SER D C   1 
ATOM   1480 O O   . SER A 1 183 ? -52.532 -17.656 25.185  1   45.55  ? 353 SER D O   1 
ATOM   1481 C CB  . SER A 1 183 ? -50.827 -15.219 23.673  1   43.26  ? 353 SER D CB  1 
ATOM   1482 O OG  . SER A 1 183 ? -50.148 -15.756 22.551  1   42.99  ? 353 SER D OG  1 
ATOM   1483 N N   . VAL A 1 184 ? -50.791 -18.353 23.958  1   46.6   ? 354 VAL D N   1 
ATOM   1484 C CA  . VAL A 1 184 ? -51.309 -19.687 23.7    1   48.3   ? 354 VAL D CA  1 
ATOM   1485 C C   . VAL A 1 184 ? -51.486 -20.441 25.023  1   48.8   ? 354 VAL D C   1 
ATOM   1486 O O   . VAL A 1 184 ? -52.541 -21.028 25.27   1   51.08  ? 354 VAL D O   1 
ATOM   1487 C CB  . VAL A 1 184 ? -50.371 -20.444 22.735  1   47.31  ? 354 VAL D CB  1 
ATOM   1488 C CG1 . VAL A 1 184 ? -50.643 -21.939 22.722  1   47.8   ? 354 VAL D CG1 1 
ATOM   1489 C CG2 . VAL A 1 184 ? -50.385 -19.875 21.32   1   47.25  ? 354 VAL D CG2 1 
ATOM   1490 N N   . ILE A 1 185 ? -50.456 -20.449 25.874  1   46.03  ? 355 ILE D N   1 
ATOM   1491 C CA  . ILE A 1 185 ? -50.603 -21.173 27.128  1   47.83  ? 355 ILE D CA  1 
ATOM   1492 C C   . ILE A 1 185 ? -51.835 -20.638 27.864  1   50.81  ? 355 ILE D C   1 
ATOM   1493 O O   . ILE A 1 185 ? -52.644 -21.408 28.371  1   53     ? 355 ILE D O   1 
ATOM   1494 C CB  . ILE A 1 185 ? -49.314 -21.142 27.981  1   45.35  ? 355 ILE D CB  1 
ATOM   1495 C CG1 . ILE A 1 185 ? -48.121 -21.709 27.206  1   43.46  ? 355 ILE D CG1 1 
ATOM   1496 C CG2 . ILE A 1 185 ? -49.511 -21.873 29.312  1   42.12  ? 355 ILE D CG2 1 
ATOM   1497 C CD1 . ILE A 1 185 ? -46.805 -21.556 27.939  1   40.22  ? 355 ILE D CD1 1 
ATOM   1498 N N   . ALA A 1 186 ? -52.019 -19.314 27.868  1   52.54  ? 356 ALA D N   1 
ATOM   1499 C CA  . ALA A 1 186 ? -53.057 -18.71  28.691  1   56.69  ? 356 ALA D CA  1 
ATOM   1500 C C   . ALA A 1 186 ? -54.447 -19.054 28.149  1   61.03  ? 356 ALA D C   1 
ATOM   1501 O O   . ALA A 1 186 ? -55.368 -19.325 28.913  1   68.06  ? 356 ALA D O   1 
ATOM   1502 C CB  . ALA A 1 186 ? -52.83  -17.222 28.805  1   53.36  ? 356 ALA D CB  1 
ATOM   1503 N N   . ALA A 1 187 ? -54.588 -19.042 26.82   1   59.25  ? 357 ALA D N   1 
ATOM   1504 C CA  . ALA A 1 187 ? -55.781 -19.531 26.156  1   58.18  ? 357 ALA D CA  1 
ATOM   1505 C C   . ALA A 1 187 ? -56.079 -20.952 26.622  1   57.29  ? 357 ALA D C   1 
ATOM   1506 O O   . ALA A 1 187 ? -57.209 -21.267 26.992  1   58.53  ? 357 ALA D O   1 
ATOM   1507 C CB  . ALA A 1 187 ? -55.575 -19.472 24.661  1   58.45  ? 357 ALA D CB  1 
ATOM   1508 N N   . ALA A 1 188 ? -55.045 -21.795 26.619  1   54.38  ? 358 ALA D N   1 
ATOM   1509 C CA  . ALA A 1 188 ? -55.226 -23.201 26.929  1   57.57  ? 358 ALA D CA  1 
ATOM   1510 C C   . ALA A 1 188 ? -55.668 -23.372 28.375  1   56.85  ? 358 ALA D C   1 
ATOM   1511 O O   . ALA A 1 188 ? -56.579 -24.138 28.673  1   60.42  ? 358 ALA D O   1 
ATOM   1512 C CB  . ALA A 1 188 ? -53.966 -23.98  26.641  1   57.46  ? 358 ALA D CB  1 
ATOM   1513 N N   . ALA A 1 189 ? -55.012 -22.64  29.266  1   54.34  ? 359 ALA D N   1 
ATOM   1514 C CA  . ALA A 1 189 ? -55.334 -22.749 30.671  1   57.16  ? 359 ALA D CA  1 
ATOM   1515 C C   . ALA A 1 189 ? -56.733 -22.191 30.945  1   61.38  ? 359 ALA D C   1 
ATOM   1516 O O   . ALA A 1 189 ? -57.4   -22.685 31.859  1   66.18  ? 359 ALA D O   1 
ATOM   1517 C CB  . ALA A 1 189 ? -54.27  -22.076 31.504  1   54.93  ? 359 ALA D CB  1 
ATOM   1518 N N   . PHE A 1 190 ? -57.177 -21.179 30.171  1   58.97  ? 360 PHE D N   1 
ATOM   1519 C CA  . PHE A 1 190 ? -58.477 -20.561 30.404  1   58.84  ? 360 PHE D CA  1 
ATOM   1520 C C   . PHE A 1 190 ? -59.593 -21.541 30.026  1   63.85  ? 360 PHE D C   1 
ATOM   1521 O O   . PHE A 1 190 ? -60.509 -21.791 30.826  1   65.63  ? 360 PHE D O   1 
ATOM   1522 C CB  . PHE A 1 190 ? -58.633 -19.193 29.74   1   56.47  ? 360 PHE D CB  1 
ATOM   1523 C CG  . PHE A 1 190 ? -59.95  -18.502 30.075  1   57.53  ? 360 PHE D CG  1 
ATOM   1524 C CD1 . PHE A 1 190 ? -60.314 -18.247 31.397  1   56.68  ? 360 PHE D CD1 1 
ATOM   1525 C CD2 . PHE A 1 190 ? -60.837 -18.132 29.066  1   59.52  ? 360 PHE D CD2 1 
ATOM   1526 C CE1 . PHE A 1 190 ? -61.512 -17.617 31.699  1   58.68  ? 360 PHE D CE1 1 
ATOM   1527 C CE2 . PHE A 1 190 ? -62.046 -17.517 29.373  1   61.44  ? 360 PHE D CE2 1 
ATOM   1528 C CZ  . PHE A 1 190 ? -62.378 -17.254 30.691  1   61.14  ? 360 PHE D CZ  1 
ATOM   1529 N N   . HIS A 1 191 ? -59.502 -22.104 28.806  1   63.02  ? 361 HIS D N   1 
ATOM   1530 C CA  . HIS A 1 191 ? -60.379 -23.198 28.416  1   63.28  ? 361 HIS D CA  1 
ATOM   1531 C C   . HIS A 1 191 ? -60.399 -24.258 29.515  1   63.88  ? 361 HIS D C   1 
ATOM   1532 O O   . HIS A 1 191 ? -61.446 -24.548 30.09   1   66.92  ? 361 HIS D O   1 
ATOM   1533 C CB  . HIS A 1 191 ? -59.948 -23.867 27.108  1   63.06  ? 361 HIS D CB  1 
ATOM   1534 C CG  . HIS A 1 191 ? -60.837 -25.022 26.804  1   66.55  ? 361 HIS D CG  1 
ATOM   1535 N ND1 . HIS A 1 191 ? -62.147 -24.864 26.4    1   70.17  ? 361 HIS D ND1 1 
ATOM   1536 C CD2 . HIS A 1 191 ? -60.65  -26.335 26.929  1   67.18  ? 361 HIS D CD2 1 
ATOM   1537 C CE1 . HIS A 1 191 ? -62.711 -26.057 26.254  1   71.87  ? 361 HIS D CE1 1 
ATOM   1538 N NE2 . HIS A 1 191 ? -61.814 -26.968 26.566  1   70.25  ? 361 HIS D NE2 1 
ATOM   1539 N N   . LEU A 1 192 ? -59.233 -24.83  29.806  1   61.84  ? 362 LEU D N   1 
ATOM   1540 C CA  . LEU A 1 192 ? -59.191 -26.004 30.652  1   64.57  ? 362 LEU D CA  1 
ATOM   1541 C C   . LEU A 1 192 ? -59.862 -25.752 32.006  1   67.76  ? 362 LEU D C   1 
ATOM   1542 O O   . LEU A 1 192 ? -60.546 -26.642 32.505  1   72.09  ? 362 LEU D O   1 
ATOM   1543 C CB  . LEU A 1 192 ? -57.761 -26.517 30.782  1   63.3   ? 362 LEU D CB  1 
ATOM   1544 C CG  . LEU A 1 192 ? -57.603 -27.871 31.478  1   65.28  ? 362 LEU D CG  1 
ATOM   1545 C CD1 . LEU A 1 192 ? -58.413 -28.974 30.79   1   67.9   ? 362 LEU D CD1 1 
ATOM   1546 C CD2 . LEU A 1 192 ? -56.133 -28.231 31.52   1   64.42  ? 362 LEU D CD2 1 
ATOM   1547 N N   . ALA A 1 193 ? -59.684 -24.556 32.596  1   67.62  ? 363 ALA D N   1 
ATOM   1548 C CA  . ALA A 1 193 ? -60.325 -24.214 33.867  1   69.79  ? 363 ALA D CA  1 
ATOM   1549 C C   . ALA A 1 193 ? -61.843 -24.053 33.696  1   74.42  ? 363 ALA D C   1 
ATOM   1550 O O   . ALA A 1 193 ? -62.648 -24.762 34.313  1   74.8   ? 363 ALA D O   1 
ATOM   1551 C CB  . ALA A 1 193 ? -59.693 -22.981 34.473  1   63.91  ? 363 ALA D CB  1 
ATOM   1552 N N   . LEU A 1 194 ? -62.232 -23.113 32.827  1   73.78  ? 364 LEU D N   1 
ATOM   1553 C CA  . LEU A 1 194 ? -63.627 -22.929 32.46   1   72.81  ? 364 LEU D CA  1 
ATOM   1554 C C   . LEU A 1 194 ? -64.332 -24.281 32.314  1   71.89  ? 364 LEU D C   1 
ATOM   1555 O O   . LEU A 1 194 ? -65.357 -24.517 32.945  1   72.83  ? 364 LEU D O   1 
ATOM   1556 C CB  . LEU A 1 194 ? -63.614 -22.112 31.168  1   72.88  ? 364 LEU D CB  1 
ATOM   1557 C CG  . LEU A 1 194 ? -64.898 -21.367 30.809  1   76.29  ? 364 LEU D CG  1 
ATOM   1558 C CD1 . LEU A 1 194 ? -65.336 -20.493 31.971  1   77.32  ? 364 LEU D CD1 1 
ATOM   1559 C CD2 . LEU A 1 194 ? -64.601 -20.533 29.573  1   75.45  ? 364 LEU D CD2 1 
ATOM   1560 N N   . TYR A 1 195 ? -63.767 -25.183 31.505  1   71.41  ? 365 TYR D N   1 
ATOM   1561 C CA  . TYR A 1 195 ? -64.366 -26.494 31.284  1   74.7   ? 365 TYR D CA  1 
ATOM   1562 C C   . TYR A 1 195 ? -64.59  -27.203 32.619  1   74.29  ? 365 TYR D C   1 
ATOM   1563 O O   . TYR A 1 195 ? -65.727 -27.486 32.965  1   76.51  ? 365 TYR D O   1 
ATOM   1564 C CB  . TYR A 1 195 ? -63.514 -27.33  30.324  1   74.12  ? 365 TYR D CB  1 
ATOM   1565 C CG  . TYR A 1 195 ? -64.136 -28.656 29.916  1   79.91  ? 365 TYR D CG  1 
ATOM   1566 C CD1 . TYR A 1 195 ? -65.509 -28.875 30.024  1   84.61  ? 365 TYR D CD1 1 
ATOM   1567 C CD2 . TYR A 1 195 ? -63.358 -29.677 29.376  1   80.8   ? 365 TYR D CD2 1 
ATOM   1568 C CE1 . TYR A 1 195 ? -66.079 -30.086 29.662  1   88.31  ? 365 TYR D CE1 1 
ATOM   1569 C CE2 . TYR A 1 195 ? -63.919 -30.889 29.005  1   85.48  ? 365 TYR D CE2 1 
ATOM   1570 C CZ  . TYR A 1 195 ? -65.285 -31.096 29.139  1   88.79  ? 365 TYR D CZ  1 
ATOM   1571 O OH  . TYR A 1 195 ? -65.845 -32.291 28.761  1   90.97  ? 365 TYR D OH  1 
ATOM   1572 N N   . THR A 1 196 ? -63.506 -27.444 33.37   1   71.2   ? 366 THR D N   1 
ATOM   1573 C CA  . THR A 1 196 ? -63.542 -28.115 34.664  1   70.87  ? 366 THR D CA  1 
ATOM   1574 C C   . THR A 1 196 ? -64.619 -27.537 35.589  1   73.56  ? 366 THR D C   1 
ATOM   1575 O O   . THR A 1 196 ? -65.351 -28.306 36.21   1   75.54  ? 366 THR D O   1 
ATOM   1576 C CB  . THR A 1 196 ? -62.175 -28.079 35.349  1   67.51  ? 366 THR D CB  1 
ATOM   1577 O OG1 . THR A 1 196 ? -61.198 -28.336 34.345  1   65.34  ? 366 THR D OG1 1 
ATOM   1578 C CG2 . THR A 1 196 ? -62.061 -29.043 36.522  1   68.3   ? 366 THR D CG2 1 
ATOM   1579 N N   . VAL A 1 197 ? -64.713 -26.199 35.703  1   73.39  ? 367 VAL D N   1 
ATOM   1580 C CA  . VAL A 1 197 ? -65.547 -25.59  36.736  1   75.32  ? 367 VAL D CA  1 
ATOM   1581 C C   . VAL A 1 197 ? -66.986 -25.396 36.255  1   80.28  ? 367 VAL D C   1 
ATOM   1582 O O   . VAL A 1 197 ? -67.901 -25.387 37.072  1   83.68  ? 367 VAL D O   1 
ATOM   1583 C CB  . VAL A 1 197 ? -64.97  -24.282 37.311  1   72.27  ? 367 VAL D CB  1 
ATOM   1584 C CG1 . VAL A 1 197 ? -65.82  -23.735 38.453  1   72.64  ? 367 VAL D CG1 1 
ATOM   1585 C CG2 . VAL A 1 197 ? -63.521 -24.448 37.763  1   69.82  ? 367 VAL D CG2 1 
ATOM   1586 N N   . THR A 1 198 ? -67.193 -25.236 34.938  1   82.61  ? 368 THR D N   1 
ATOM   1587 C CA  . THR A 1 198 ? -68.508 -24.873 34.42   1   85.06  ? 368 THR D CA  1 
ATOM   1588 C C   . THR A 1 198 ? -69.017 -25.872 33.385  1   87.38  ? 368 THR D C   1 
ATOM   1589 O O   . THR A 1 198 ? -70.222 -26.003 33.209  1   89.87  ? 368 THR D O   1 
ATOM   1590 C CB  . THR A 1 198 ? -68.493 -23.457 33.844  1   82.76  ? 368 THR D CB  1 
ATOM   1591 O OG1 . THR A 1 198 ? -67.549 -23.474 32.776  1   83.55  ? 368 THR D OG1 1 
ATOM   1592 C CG2 . THR A 1 198 ? -68.134 -22.417 34.888  1   79.07  ? 368 THR D CG2 1 
ATOM   1593 N N   . GLY A 1 199 ? -68.101 -26.526 32.664  1   88.03  ? 369 GLY D N   1 
ATOM   1594 C CA  . GLY A 1 199 ? -68.481 -27.312 31.5    1   92.7   ? 369 GLY D CA  1 
ATOM   1595 C C   . GLY A 1 199 ? -68.518 -26.43  30.256  1   93.45  ? 369 GLY D C   1 
ATOM   1596 O O   . GLY A 1 199 ? -68.78  -26.913 29.153  1   93.5   ? 369 GLY D O   1 
ATOM   1597 N N   . GLN A 1 200 ? -68.244 -25.14  30.46   1   92.48  ? 370 GLN D N   1 
ATOM   1598 C CA  . GLN A 1 200 ? -68.236 -24.181 29.33   1   92.6   ? 370 GLN D CA  1 
ATOM   1599 C C   . GLN A 1 200 ? -66.916 -24.307 28.562  1   91.12  ? 370 GLN D C   1 
ATOM   1600 O O   . GLN A 1 200 ? -66.062 -25.104 28.975  1   91.4   ? 370 GLN D O   1 
ATOM   1601 C CB  . GLN A 1 200 ? -68.451 -22.777 29.881  1   92.51  ? 370 GLN D CB  1 
ATOM   1602 C CG  . GLN A 1 200 ? -69.82  -22.572 30.516  1   98.85  ? 370 GLN D CG  1 
ATOM   1603 C CD  . GLN A 1 200 ? -70.064 -21.144 30.948  1   100.01 ? 370 GLN D CD  1 
ATOM   1604 O OE1 . GLN A 1 200 ? -69.431 -20.204 30.456  1   95.05  ? 370 GLN D OE1 1 
ATOM   1605 N NE2 . GLN A 1 200 ? -70.992 -20.969 31.877  1   103.53 ? 370 GLN D NE2 1 
ATOM   1606 N N   . SER A 1 201 ? -66.751 -23.538 27.488  1   89.57  ? 371 SER D N   1 
ATOM   1607 C CA  . SER A 1 201 ? -65.539 -23.711 26.654  1   88.03  ? 371 SER D CA  1 
ATOM   1608 C C   . SER A 1 201 ? -64.986 -22.371 26.152  1   89.23  ? 371 SER D C   1 
ATOM   1609 O O   . SER A 1 201 ? -65.672 -21.349 26.327  1   95.71  ? 371 SER D O   1 
ATOM   1610 C CB  . SER A 1 201 ? -65.84  -24.616 25.501  1   89.1   ? 371 SER D CB  1 
ATOM   1611 O OG  . SER A 1 201 ? -66.156 -25.923 25.957  1   94.37  ? 371 SER D OG  1 
ATOM   1612 N N   . TRP A 1 202 ? -63.793 -22.392 25.551  1   83.57  ? 372 TRP D N   1 
ATOM   1613 C CA  . TRP A 1 202 ? -63.165 -21.175 24.986  1   77.66  ? 372 TRP D CA  1 
ATOM   1614 C C   . TRP A 1 202 ? -64.242 -20.322 24.348  1   80.77  ? 372 TRP D C   1 
ATOM   1615 O O   . TRP A 1 202 ? -64.846 -20.76  23.355  1   84.55  ? 372 TRP D O   1 
ATOM   1616 C CB  . TRP A 1 202 ? -62.11  -21.598 23.959  1   76.05  ? 372 TRP D CB  1 
ATOM   1617 C CG  . TRP A 1 202 ? -61.228 -20.51  23.405  1   74.59  ? 372 TRP D CG  1 
ATOM   1618 C CD1 . TRP A 1 202 ? -61.018 -20.245 22.085  1   74.89  ? 372 TRP D CD1 1 
ATOM   1619 C CD2 . TRP A 1 202 ? -60.401 -19.578 24.136  1   74.19  ? 372 TRP D CD2 1 
ATOM   1620 N NE1 . TRP A 1 202 ? -60.142 -19.206 21.939  1   74.13  ? 372 TRP D NE1 1 
ATOM   1621 C CE2 . TRP A 1 202 ? -59.744 -18.778 23.176  1   71.52  ? 372 TRP D CE2 1 
ATOM   1622 C CE3 . TRP A 1 202 ? -60.157 -19.337 25.492  1   73.06  ? 372 TRP D CE3 1 
ATOM   1623 C CZ2 . TRP A 1 202 ? -58.866 -17.76  23.533  1   65.73  ? 372 TRP D CZ2 1 
ATOM   1624 C CZ3 . TRP A 1 202 ? -59.288 -18.33  25.841  1   70.77  ? 372 TRP D CZ3 1 
ATOM   1625 C CH2 . TRP A 1 202 ? -58.653 -17.553 24.874  1   67.12  ? 372 TRP D CH2 1 
ATOM   1626 N N   . PRO A 1 203 ? -64.515 -19.118 24.882  1   79.4   ? 373 PRO D N   1 
ATOM   1627 C CA  . PRO A 1 203 ? -65.586 -18.289 24.356  1   79.87  ? 373 PRO D CA  1 
ATOM   1628 C C   . PRO A 1 203 ? -65.329 -17.798 22.944  1   78.09  ? 373 PRO D C   1 
ATOM   1629 O O   . PRO A 1 203 ? -64.163 -17.627 22.569  1   74.86  ? 373 PRO D O   1 
ATOM   1630 C CB  . PRO A 1 203 ? -65.616 -17.152 25.378  1   78.93  ? 373 PRO D CB  1 
ATOM   1631 C CG  . PRO A 1 203 ? -64.972 -17.74  26.607  1   77.68  ? 373 PRO D CG  1 
ATOM   1632 C CD  . PRO A 1 203 ? -63.835 -18.546 26.021  1   77.13  ? 373 PRO D CD  1 
ATOM   1633 N N   . GLU A 1 204 ? -66.4   -17.577 22.178  1   78.25  ? 374 GLU D N   1 
ATOM   1634 C CA  . GLU A 1 204 ? -66.268 -17.051 20.796  1   78.37  ? 374 GLU D CA  1 
ATOM   1635 C C   . GLU A 1 204 ? -65.72  -15.634 20.887  1   77.97  ? 374 GLU D C   1 
ATOM   1636 O O   . GLU A 1 204 ? -64.852 -15.28  20.074  1   77.15  ? 374 GLU D O   1 
ATOM   1637 C CB  . GLU A 1 204 ? -67.616 -17.061 20.082  1   80.77  ? 374 GLU D CB  1 
ATOM   1638 C CG  . GLU A 1 204 ? -67.545 -16.557 18.645  1   81.87  ? 374 GLU D CG  1 
ATOM   1639 C CD  . GLU A 1 204 ? -66.747 -17.441 17.708  1   81.42  ? 374 GLU D CD  1 
ATOM   1640 O OE1 . GLU A 1 204 ? -66.718 -18.667 17.937  1   80.9   ? 374 GLU D OE1 1 
ATOM   1641 O OE2 . GLU A 1 204 ? -66.158 -16.907 16.747  1   81.03  ? 374 GLU D OE2 1 
ATOM   1642 N N   . SER A 1 205 ? -66.248 -14.848 21.818  1   79.47  ? 375 SER D N   1 
ATOM   1643 C CA  . SER A 1 205 ? -65.693 -13.524 22.068  1   78.28  ? 375 SER D CA  1 
ATOM   1644 C C   . SER A 1 205 ? -64.159 -13.549 22.017  1   75.51  ? 375 SER D C   1 
ATOM   1645 O O   . SER A 1 205 ? -63.562 -12.676 21.386  1   74.24  ? 375 SER D O   1 
ATOM   1646 C CB  . SER A 1 205 ? -66.197 -12.987 23.377  1   77.52  ? 375 SER D CB  1 
ATOM   1647 O OG  . SER A 1 205 ? -66.121 -14.012 24.359  1   79.41  ? 375 SER D OG  1 
ATOM   1648 N N   . LEU A 1 206 ? -63.541 -14.573 22.636  1   71.73  ? 376 LEU D N   1 
ATOM   1649 C CA  . LEU A 1 206 ? -62.093 -14.696 22.715  1   67.45  ? 376 LEU D CA  1 
ATOM   1650 C C   . LEU A 1 206 ? -61.513 -15.387 21.485  1   66.7   ? 376 LEU D C   1 
ATOM   1651 O O   . LEU A 1 206 ? -60.298 -15.454 21.341  1   64.56  ? 376 LEU D O   1 
ATOM   1652 C CB  . LEU A 1 206 ? -61.686 -15.44  23.984  1   66.53  ? 376 LEU D CB  1 
ATOM   1653 C CG  . LEU A 1 206 ? -61.769 -14.637 25.282  1   66.09  ? 376 LEU D CG  1 
ATOM   1654 C CD1 . LEU A 1 206 ? -61.515 -15.525 26.491  1   66.82  ? 376 LEU D CD1 1 
ATOM   1655 C CD2 . LEU A 1 206 ? -60.773 -13.488 25.266  1   64.37  ? 376 LEU D CD2 1 
ATOM   1656 N N   . VAL A 1 207 ? -62.378 -15.928 20.625  1   70.27  ? 377 VAL D N   1 
ATOM   1657 C CA  . VAL A 1 207 ? -61.894 -16.507 19.384  1   73.72  ? 377 VAL D CA  1 
ATOM   1658 C C   . VAL A 1 207 ? -61.674 -15.367 18.402  1   73.67  ? 377 VAL D C   1 
ATOM   1659 O O   . VAL A 1 207 ? -60.777 -15.409 17.56   1   72.13  ? 377 VAL D O   1 
ATOM   1660 C CB  . VAL A 1 207 ? -62.879 -17.547 18.818  1   79.05  ? 377 VAL D CB  1 
ATOM   1661 C CG1 . VAL A 1 207 ? -62.44  -18.072 17.455  1   80.17  ? 377 VAL D CG1 1 
ATOM   1662 C CG2 . VAL A 1 207 ? -63.088 -18.694 19.802  1   82.48  ? 377 VAL D CG2 1 
ATOM   1663 N N   . GLN A 1 208 ? -62.515 -14.346 18.554  1   75.52  ? 378 GLN D N   1 
ATOM   1664 C CA  . GLN A 1 208 ? -62.454 -13.162 17.725  1   78.4   ? 378 GLN D CA  1 
ATOM   1665 C C   . GLN A 1 208 ? -61.278 -12.287 18.15   1   74.46  ? 378 GLN D C   1 
ATOM   1666 O O   . GLN A 1 208 ? -60.652 -11.657 17.298  1   74.34  ? 378 GLN D O   1 
ATOM   1667 C CB  . GLN A 1 208 ? -63.788 -12.433 17.849  1   86.98  ? 378 GLN D CB  1 
ATOM   1668 C CG  . GLN A 1 208 ? -64.959 -13.227 17.284  1   94.37  ? 378 GLN D CG  1 
ATOM   1669 C CD  . GLN A 1 208 ? -64.863 -13.398 15.785  1   97.84  ? 378 GLN D CD  1 
ATOM   1670 O OE1 . GLN A 1 208 ? -65.381 -14.371 15.23   1   102.17 ? 378 GLN D OE1 1 
ATOM   1671 N NE2 . GLN A 1 208 ? -64.152 -12.489 15.126  1   96.09  ? 378 GLN D NE2 1 
ATOM   1672 N N   . LYS A 1 209 ? -60.985 -12.262 19.457  1   71.15  ? 379 LYS D N   1 
ATOM   1673 C CA  . LYS A 1 209 ? -59.87  -11.496 20.002  1   68.01  ? 379 LYS D CA  1 
ATOM   1674 C C   . LYS A 1 209 ? -58.537 -12.129 19.601  1   66.37  ? 379 LYS D C   1 
ATOM   1675 O O   . LYS A 1 209 ? -57.707 -11.469 18.982  1   63.83  ? 379 LYS D O   1 
ATOM   1676 C CB  . LYS A 1 209 ? -60     -11.376 21.525  1   64.88  ? 379 LYS D CB  1 
ATOM   1677 C CG  . LYS A 1 209 ? -59.01  -10.447 22.205  1   62.68  ? 379 LYS D CG  1 
ATOM   1678 C CD  . LYS A 1 209 ? -59.08  -10.491 23.73   1   61.83  ? 379 LYS D CD  1 
ATOM   1679 C CE  . LYS A 1 209 ? -58.48  -9.295  24.418  1   59.05  ? 379 LYS D CE  1 
ATOM   1680 N NZ  . LYS A 1 209 ? -59.244 -8.056  24.196  1   58.51  ? 379 LYS D NZ  1 
ATOM   1681 N N   . THR A 1 210 ? -58.365 -13.423 19.927  1   67.81  ? 380 THR D N   1 
ATOM   1682 C CA  . THR A 1 210 ? -57.086 -14.119 19.833  1   64.35  ? 380 THR D CA  1 
ATOM   1683 C C   . THR A 1 210 ? -56.829 -14.691 18.435  1   63.61  ? 380 THR D C   1 
ATOM   1684 O O   . THR A 1 210 ? -55.677 -14.798 18.019  1   61.01  ? 380 THR D O   1 
ATOM   1685 C CB  . THR A 1 210 ? -57.017 -15.213 20.899  1   64.52  ? 380 THR D CB  1 
ATOM   1686 O OG1 . THR A 1 210 ? -57.997 -16.21  20.607  1   70.06  ? 380 THR D OG1 1 
ATOM   1687 C CG2 . THR A 1 210 ? -57.24  -14.63  22.281  1   62.63  ? 380 THR D CG2 1 
ATOM   1688 N N   . GLY A 1 211 ? -57.884 -15.106 17.726  1   64.5   ? 381 GLY D N   1 
ATOM   1689 C CA  . GLY A 1 211 ? -57.684 -15.787 16.461  1   66.42  ? 381 GLY D CA  1 
ATOM   1690 C C   . GLY A 1 211 ? -57.273 -17.229 16.731  1   67.62  ? 381 GLY D C   1 
ATOM   1691 O O   . GLY A 1 211 ? -56.738 -17.908 15.859  1   69.76  ? 381 GLY D O   1 
ATOM   1692 N N   . TYR A 1 212 ? -57.54  -17.673 17.964  1   66.83  ? 382 TYR D N   1 
ATOM   1693 C CA  . TYR A 1 212 ? -57.203 -19.011 18.413  1   65.75  ? 382 TYR D CA  1 
ATOM   1694 C C   . TYR A 1 212 ? -58.486 -19.83  18.465  1   69.69  ? 382 TYR D C   1 
ATOM   1695 O O   . TYR A 1 212 ? -59.47  -19.378 19.065  1   68.59  ? 382 TYR D O   1 
ATOM   1696 C CB  . TYR A 1 212 ? -56.577 -18.982 19.809  1   60.13  ? 382 TYR D CB  1 
ATOM   1697 C CG  . TYR A 1 212 ? -55.19  -18.374 19.931  1   56     ? 382 TYR D CG  1 
ATOM   1698 C CD1 . TYR A 1 212 ? -54.285 -18.392 18.873  1   54.59  ? 382 TYR D CD1 1 
ATOM   1699 C CD2 . TYR A 1 212 ? -54.785 -17.803 21.138  1   54.4   ? 382 TYR D CD2 1 
ATOM   1700 C CE1 . TYR A 1 212 ? -53.026 -17.828 19.015  1   53.83  ? 382 TYR D CE1 1 
ATOM   1701 C CE2 . TYR A 1 212 ? -53.523 -17.253 21.297  1   52.01  ? 382 TYR D CE2 1 
ATOM   1702 C CZ  . TYR A 1 212 ? -52.641 -17.259 20.228  1   53.02  ? 382 TYR D CZ  1 
ATOM   1703 O OH  . TYR A 1 212 ? -51.404 -16.698 20.423  1   51.12  ? 382 TYR D OH  1 
ATOM   1704 N N   . THR A 1 213 ? -58.455 -21.008 17.823  1   73.31  ? 383 THR D N   1 
ATOM   1705 C CA  . THR A 1 213 ? -59.548 -21.97  17.897  1   76.76  ? 383 THR D CA  1 
ATOM   1706 C C   . THR A 1 213 ? -59.132 -23.141 18.783  1   74.47  ? 383 THR D C   1 
ATOM   1707 O O   . THR A 1 213 ? -57.939 -23.384 18.96   1   74.51  ? 383 THR D O   1 
ATOM   1708 C CB  . THR A 1 213 ? -59.936 -22.409 16.489  1   80.64  ? 383 THR D CB  1 
ATOM   1709 O OG1 . THR A 1 213 ? -58.77  -22.981 15.896  1   80.36  ? 383 THR D OG1 1 
ATOM   1710 C CG2 . THR A 1 213 ? -60.459 -21.238 15.678  1   82.75  ? 383 THR D CG2 1 
ATOM   1711 N N   . LEU A 1 214 ? -60.12  -23.85  19.34   1   73.82  ? 384 LEU D N   1 
ATOM   1712 C CA  . LEU A 1 214 ? -59.811 -25.029 20.13   1   74.87  ? 384 LEU D CA  1 
ATOM   1713 C C   . LEU A 1 214 ? -58.974 -26.011 19.306  1   79.34  ? 384 LEU D C   1 
ATOM   1714 O O   . LEU A 1 214 ? -58.342 -26.926 19.851  1   83.99  ? 384 LEU D O   1 
ATOM   1715 C CB  . LEU A 1 214 ? -61.062 -25.661 20.733  1   73.81  ? 384 LEU D CB  1 
ATOM   1716 C CG  . LEU A 1 214 ? -61.437 -25.145 22.127  1   72.79  ? 384 LEU D CG  1 
ATOM   1717 C CD1 . LEU A 1 214 ? -62.666 -25.843 22.682  1   73.86  ? 384 LEU D CD1 1 
ATOM   1718 C CD2 . LEU A 1 214 ? -60.261 -25.232 23.111  1   69.4   ? 384 LEU D CD2 1 
ATOM   1719 N N   . GLU A 1 215 ? -58.973 -25.791 17.986  1   79.02  ? 385 GLU D N   1 
ATOM   1720 C CA  . GLU A 1 215 ? -58.184 -26.575 17.058  1   77.18  ? 385 GLU D CA  1 
ATOM   1721 C C   . GLU A 1 215 ? -56.742 -26.101 17.164  1   73.1   ? 385 GLU D C   1 
ATOM   1722 O O   . GLU A 1 215 ? -55.828 -26.911 17.264  1   74.73  ? 385 GLU D O   1 
ATOM   1723 C CB  . GLU A 1 215 ? -58.747 -26.427 15.645  1   79.81  ? 385 GLU D CB  1 
ATOM   1724 C CG  . GLU A 1 215 ? -58.184 -27.429 14.643  1   82.41  ? 385 GLU D CG  1 
ATOM   1725 C CD  . GLU A 1 215 ? -58.948 -27.38  13.323  1   89.64  ? 385 GLU D CD  1 
ATOM   1726 O OE1 . GLU A 1 215 ? -59.57  -28.392 12.93   1   93.78  ? 385 GLU D OE1 1 
ATOM   1727 O OE2 . GLU A 1 215 ? -58.951 -26.31  12.683  1   90.36  ? 385 GLU D OE2 1 
ATOM   1728 N N   . THR A 1 216 ? -56.56  -24.777 17.148  1   71.65  ? 386 THR D N   1 
ATOM   1729 C CA  . THR A 1 216 ? -55.233 -24.188 17.245  1   70.96  ? 386 THR D CA  1 
ATOM   1730 C C   . THR A 1 216 ? -54.648 -24.502 18.618  1   68.7   ? 386 THR D C   1 
ATOM   1731 O O   . THR A 1 216 ? -53.459 -24.796 18.725  1   65.73  ? 386 THR D O   1 
ATOM   1732 C CB  . THR A 1 216 ? -55.233 -22.689 16.93   1   71.17  ? 386 THR D CB  1 
ATOM   1733 O OG1 . THR A 1 216 ? -56.076 -22.023 17.866  1   74.98  ? 386 THR D OG1 1 
ATOM   1734 C CG2 . THR A 1 216 ? -55.7   -22.381 15.518  1   71.97  ? 386 THR D CG2 1 
ATOM   1735 N N   . LEU A 1 217 ? -55.514 -24.516 19.64   1   71.68  ? 387 LEU D N   1 
ATOM   1736 C CA  . LEU A 1 217 ? -55.087 -24.631 21.028  1   73.38  ? 387 LEU D CA  1 
ATOM   1737 C C   . LEU A 1 217 ? -55.012 -26.077 21.525  1   75.31  ? 387 LEU D C   1 
ATOM   1738 O O   . LEU A 1 217 ? -55.058 -26.289 22.735  1   73.13  ? 387 LEU D O   1 
ATOM   1739 C CB  . LEU A 1 217 ? -56.069 -23.858 21.91   1   73.32  ? 387 LEU D CB  1 
ATOM   1740 C CG  . LEU A 1 217 ? -56.132 -22.345 21.719  1   70.9   ? 387 LEU D CG  1 
ATOM   1741 C CD1 . LEU A 1 217 ? -57.172 -21.769 22.678  1   73.03  ? 387 LEU D CD1 1 
ATOM   1742 C CD2 . LEU A 1 217 ? -54.766 -21.747 21.961  1   68.28  ? 387 LEU D CD2 1 
ATOM   1743 N N   . LYS A 1 218 ? -54.92  -27.071 20.632  1   77.61  ? 388 LYS D N   1 
ATOM   1744 C CA  . LYS A 1 218 ? -55.028 -28.451 21.085  1   79.15  ? 388 LYS D CA  1 
ATOM   1745 C C   . LYS A 1 218 ? -53.66  -29.052 21.445  1   75.91  ? 388 LYS D C   1 
ATOM   1746 O O   . LYS A 1 218 ? -53.528 -29.716 22.477  1   71.25  ? 388 LYS D O   1 
ATOM   1747 C CB  . LYS A 1 218 ? -55.853 -29.279 20.098  1   82.66  ? 388 LYS D CB  1 
ATOM   1748 C CG  . LYS A 1 218 ? -56.42  -30.567 20.668  1   84.38  ? 388 LYS D CG  1 
ATOM   1749 C CD  . LYS A 1 218 ? -57.204 -31.328 19.603  1   87.47  ? 388 LYS D CD  1 
ATOM   1750 C CE  . LYS A 1 218 ? -56.463 -31.566 18.329  1   83.84  ? 388 LYS D CE  1 
ATOM   1751 N NZ  . LYS A 1 218 ? -57.328 -32.364 17.463  1   87.25  ? 388 LYS D NZ  1 
ATOM   1752 N N   . PRO A 1 219 ? -52.59  -28.865 20.632  1   72.8   ? 389 PRO D N   1 
ATOM   1753 C CA  . PRO A 1 219 ? -51.277 -29.367 21.039  1   70.3   ? 389 PRO D CA  1 
ATOM   1754 C C   . PRO A 1 219 ? -50.995 -28.955 22.484  1   70.22  ? 389 PRO D C   1 
ATOM   1755 O O   . PRO A 1 219 ? -50.64  -29.823 23.28   1   70.39  ? 389 PRO D O   1 
ATOM   1756 C CB  . PRO A 1 219 ? -50.313 -28.804 19.996  1   67.45  ? 389 PRO D CB  1 
ATOM   1757 C CG  . PRO A 1 219 ? -51.204 -28.662 18.778  1   70.91  ? 389 PRO D CG  1 
ATOM   1758 C CD  . PRO A 1 219 ? -52.584 -28.224 19.3    1   71.61  ? 389 PRO D CD  1 
ATOM   1759 N N   . CYS A 1 220 ? -51.246 -27.672 22.822  1   67.35  ? 390 CYS D N   1 
ATOM   1760 C CA  . CYS A 1 220 ? -51.028 -27.118 24.153  1   64.35  ? 390 CYS D CA  1 
ATOM   1761 C C   . CYS A 1 220 ? -51.999 -27.727 25.172  1   64.8   ? 390 CYS D C   1 
ATOM   1762 O O   . CYS A 1 220 ? -51.6   -28.165 26.257  1   64.75  ? 390 CYS D O   1 
ATOM   1763 C CB  . CYS A 1 220 ? -51.119 -25.59  24.143  1   61.77  ? 390 CYS D CB  1 
ATOM   1764 S SG  . CYS A 1 220 ? -50.398 -24.759 25.597  1   56.43  ? 390 CYS D SG  1 
ATOM   1765 N N   . LEU A 1 221 ? -53.288 -27.73  24.824  1   63.54  ? 391 LEU D N   1 
ATOM   1766 C CA  . LEU A 1 221 ? -54.339 -28.162 25.73   1   65.25  ? 391 LEU D CA  1 
ATOM   1767 C C   . LEU A 1 221 ? -54.135 -29.617 26.164  1   67.73  ? 391 LEU D C   1 
ATOM   1768 O O   . LEU A 1 221 ? -54.528 -29.984 27.278  1   70.25  ? 391 LEU D O   1 
ATOM   1769 C CB  . LEU A 1 221 ? -55.676 -27.954 25.02   1   67.09  ? 391 LEU D CB  1 
ATOM   1770 C CG  . LEU A 1 221 ? -56.897 -27.718 25.912  1   67.6   ? 391 LEU D CG  1 
ATOM   1771 C CD1 . LEU A 1 221 ? -56.638 -26.642 26.974  1   64.04  ? 391 LEU D CD1 1 
ATOM   1772 C CD2 . LEU A 1 221 ? -58.095 -27.357 25.041  1   67.75  ? 391 LEU D CD2 1 
ATOM   1773 N N   . LEU A 1 222 ? -53.503 -30.421 25.295  1   65.46  ? 392 LEU D N   1 
ATOM   1774 C CA  . LEU A 1 222 ? -53.214 -31.823 25.575  1   65.01  ? 392 LEU D CA  1 
ATOM   1775 C C   . LEU A 1 222 ? -52.034 -31.941 26.544  1   61.8   ? 392 LEU D C   1 
ATOM   1776 O O   . LEU A 1 222 ? -52.077 -32.749 27.464  1   64.98  ? 392 LEU D O   1 
ATOM   1777 C CB  . LEU A 1 222 ? -52.99  -32.608 24.278  1   63.75  ? 392 LEU D CB  1 
ATOM   1778 C CG  . LEU A 1 222 ? -54.187 -32.704 23.327  1   63.46  ? 392 LEU D CG  1 
ATOM   1779 C CD1 . LEU A 1 222 ? -53.796 -33.279 21.984  1   63.18  ? 392 LEU D CD1 1 
ATOM   1780 C CD2 . LEU A 1 222 ? -55.212 -33.58  23.995  1   63.33  ? 392 LEU D CD2 1 
ATOM   1781 N N   . ASP A 1 223 ? -50.987 -31.138 26.33   1   56.38  ? 393 ASP D N   1 
ATOM   1782 C CA  . ASP A 1 223 ? -49.819 -31.151 27.193  1   53.65  ? 393 ASP D CA  1 
ATOM   1783 C C   . ASP A 1 223 ? -50.183 -30.698 28.61   1   53.45  ? 393 ASP D C   1 
ATOM   1784 O O   . ASP A 1 223 ? -49.559 -31.149 29.572  1   52.55  ? 393 ASP D O   1 
ATOM   1785 C CB  . ASP A 1 223 ? -48.675 -30.372 26.566  1   51.39  ? 393 ASP D CB  1 
ATOM   1786 C CG  . ASP A 1 223 ? -47.995 -31.075 25.407  1   52.81  ? 393 ASP D CG  1 
ATOM   1787 O OD1 . ASP A 1 223 ? -48.268 -32.279 25.253  1   59.03  ? 393 ASP D OD1 1 
ATOM   1788 O OD2 . ASP A 1 223 ? -47.207 -30.426 24.685  1   48.53  ? 393 ASP D OD2 1 
ATOM   1789 N N   . LEU A 1 224 ? -51.184 -29.812 28.731  1   53.29  ? 394 LEU D N   1 
ATOM   1790 C CA  . LEU A 1 224 ? -51.541 -29.214 30.01   1   51.53  ? 394 LEU D CA  1 
ATOM   1791 C C   . LEU A 1 224 ? -52.576 -30.081 30.727  1   55.21  ? 394 LEU D C   1 
ATOM   1792 O O   . LEU A 1 224 ? -52.668 -30.057 31.957  1   54.89  ? 394 LEU D O   1 
ATOM   1793 C CB  . LEU A 1 224 ? -52.052 -27.794 29.766  1   48.58  ? 394 LEU D CB  1 
ATOM   1794 C CG  . LEU A 1 224 ? -52.122 -26.881 30.994  1   45.09  ? 394 LEU D CG  1 
ATOM   1795 C CD1 . LEU A 1 224 ? -50.767 -26.496 31.487  1   42.37  ? 394 LEU D CD1 1 
ATOM   1796 C CD2 . LEU A 1 224 ? -52.86  -25.61  30.675  1   44.38  ? 394 LEU D CD2 1 
ATOM   1797 N N   . HIS A 1 225 ? -53.378 -30.814 29.947  1   57.3   ? 395 HIS D N   1 
ATOM   1798 C CA  . HIS A 1 225 ? -54.308 -31.775 30.51   1   60.21  ? 395 HIS D CA  1 
ATOM   1799 C C   . HIS A 1 225 ? -53.483 -32.853 31.216  1   62.41  ? 395 HIS D C   1 
ATOM   1800 O O   . HIS A 1 225 ? -53.757 -33.209 32.364  1   64.88  ? 395 HIS D O   1 
ATOM   1801 C CB  . HIS A 1 225 ? -55.201 -32.322 29.392  1   61.54  ? 395 HIS D CB  1 
ATOM   1802 C CG  . HIS A 1 225 ? -56.256 -33.267 29.849  1   63.63  ? 395 HIS D CG  1 
ATOM   1803 N ND1 . HIS A 1 225 ? -57.008 -33.06  30.987  1   64.06  ? 395 HIS D ND1 1 
ATOM   1804 C CD2 . HIS A 1 225 ? -56.685 -34.409 29.313  1   65.67  ? 395 HIS D CD2 1 
ATOM   1805 C CE1 . HIS A 1 225 ? -57.867 -34.053 31.126  1   67.36  ? 395 HIS D CE1 1 
ATOM   1806 N NE2 . HIS A 1 225 ? -57.688 -34.882 30.123  1   68.78  ? 395 HIS D NE2 1 
ATOM   1807 N N   . GLN A 1 226 ? -52.442 -33.325 30.516  1   61     ? 396 GLN D N   1 
ATOM   1808 C CA  . GLN A 1 226 ? -51.528 -34.328 31.028  1   61.01  ? 396 GLN D CA  1 
ATOM   1809 C C   . GLN A 1 226 ? -50.846 -33.778 32.283  1   59.01  ? 396 GLN D C   1 
ATOM   1810 O O   . GLN A 1 226 ? -50.784 -34.463 33.304  1   60.23  ? 396 GLN D O   1 
ATOM   1811 C CB  . GLN A 1 226 ? -50.544 -34.701 29.917  1   62.15  ? 396 GLN D CB  1 
ATOM   1812 C CG  . GLN A 1 226 ? -50.209 -36.18  29.817  1   70.78  ? 396 GLN D CG  1 
ATOM   1813 C CD  . GLN A 1 226 ? -51.378 -37.054 29.394  1   82.25  ? 396 GLN D CD  1 
ATOM   1814 O OE1 . GLN A 1 226 ? -52.435 -36.562 28.974  1   87.73  ? 396 GLN D OE1 1 
ATOM   1815 N NE2 . GLN A 1 226 ? -51.214 -38.372 29.49   1   81.92  ? 396 GLN D NE2 1 
ATOM   1816 N N   . THR A 1 227 ? -50.386 -32.515 32.2    1   55.61  ? 397 THR D N   1 
ATOM   1817 C CA  . THR A 1 227 ? -49.724 -31.834 33.306  1   52.84  ? 397 THR D CA  1 
ATOM   1818 C C   . THR A 1 227 ? -50.676 -31.759 34.499  1   53.3   ? 397 THR D C   1 
ATOM   1819 O O   . THR A 1 227 ? -50.268 -32.034 35.627  1   55.63  ? 397 THR D O   1 
ATOM   1820 C CB  . THR A 1 227 ? -49.171 -30.477 32.849  1   49.71  ? 397 THR D CB  1 
ATOM   1821 O OG1 . THR A 1 227 ? -47.913 -30.726 32.233  1   48.29  ? 397 THR D OG1 1 
ATOM   1822 C CG2 . THR A 1 227 ? -48.928 -29.48  33.967  1   47.96  ? 397 THR D CG2 1 
ATOM   1823 N N   . TYR A 1 228 ? -51.952 -31.448 34.235  1   51.98  ? 398 TYR D N   1 
ATOM   1824 C CA  . TYR A 1 228 ? -52.937 -31.296 35.288  1   52.82  ? 398 TYR D CA  1 
ATOM   1825 C C   . TYR A 1 228 ? -53.188 -32.649 35.937  1   58.62  ? 398 TYR D C   1 
ATOM   1826 O O   . TYR A 1 228 ? -53.435 -32.708 37.143  1   61.8   ? 398 TYR D O   1 
ATOM   1827 C CB  . TYR A 1 228 ? -54.186 -30.648 34.69   1   51.12  ? 398 TYR D CB  1 
ATOM   1828 C CG  . TYR A 1 228 ? -55.276 -30.221 35.661  1   50.59  ? 398 TYR D CG  1 
ATOM   1829 C CD1 . TYR A 1 228 ? -55.052 -30.174 37.032  1   50.13  ? 398 TYR D CD1 1 
ATOM   1830 C CD2 . TYR A 1 228 ? -56.526 -29.846 35.185  1   51.28  ? 398 TYR D CD2 1 
ATOM   1831 C CE1 . TYR A 1 228 ? -56.058 -29.785 37.9    1   51.94  ? 398 TYR D CE1 1 
ATOM   1832 C CE2 . TYR A 1 228 ? -57.532 -29.443 36.04   1   52.72  ? 398 TYR D CE2 1 
ATOM   1833 C CZ  . TYR A 1 228 ? -57.297 -29.418 37.404  1   53.27  ? 398 TYR D CZ  1 
ATOM   1834 O OH  . TYR A 1 228 ? -58.26  -29.008 38.277  1   55.75  ? 398 TYR D OH  1 
ATOM   1835 N N   . LEU A 1 229 ? -53.141 -33.72  35.129  1   62.43  ? 399 LEU D N   1 
ATOM   1836 C CA  . LEU A 1 229 ? -53.531 -35.052 35.573  1   67.92  ? 399 LEU D CA  1 
ATOM   1837 C C   . LEU A 1 229 ? -52.427 -35.688 36.415  1   74.4   ? 399 LEU D C   1 
ATOM   1838 O O   . LEU A 1 229 ? -52.733 -36.387 37.383  1   80.31  ? 399 LEU D O   1 
ATOM   1839 C CB  . LEU A 1 229 ? -53.901 -35.926 34.377  1   65.03  ? 399 LEU D CB  1 
ATOM   1840 C CG  . LEU A 1 229 ? -55.27  -35.659 33.749  1   64.03  ? 399 LEU D CG  1 
ATOM   1841 C CD1 . LEU A 1 229 ? -55.294 -36.167 32.324  1   63.58  ? 399 LEU D CD1 1 
ATOM   1842 C CD2 . LEU A 1 229 ? -56.372 -36.303 34.565  1   65.52  ? 399 LEU D CD2 1 
ATOM   1843 N N   . ARG A 1 230 ? -51.156 -35.448 36.044  1   77.18  ? 400 ARG D N   1 
ATOM   1844 C CA  . ARG A 1 230 ? -50.009 -36.05  36.715  1   78.15  ? 400 ARG D CA  1 
ATOM   1845 C C   . ARG A 1 230 ? -49.437 -35.118 37.791  1   71.45  ? 400 ARG D C   1 
ATOM   1846 O O   . ARG A 1 230 ? -48.383 -35.425 38.356  1   68.55  ? 400 ARG D O   1 
ATOM   1847 C CB  . ARG A 1 230 ? -48.942 -36.452 35.687  1   83.79  ? 400 ARG D CB  1 
ATOM   1848 C CG  . ARG A 1 230 ? -49.475 -36.958 34.354  1   94.27  ? 400 ARG D CG  1 
ATOM   1849 C CD  . ARG A 1 230 ? -48.432 -37.769 33.597  1   104.04 ? 400 ARG D CD  1 
ATOM   1850 N NE  . ARG A 1 230 ? -48.385 -37.531 32.146  1   108.46 ? 400 ARG D NE  1 
ATOM   1851 C CZ  . ARG A 1 230 ? -47.498 -38.079 31.303  1   105.07 ? 400 ARG D CZ  1 
ATOM   1852 N NH1 . ARG A 1 230 ? -46.737 -39.092 31.679  1   106.87 ? 400 ARG D NH1 1 
ATOM   1853 N NH2 . ARG A 1 230 ? -47.413 -37.653 30.053  1   100.59 ? 400 ARG D NH2 1 
ATOM   1854 N N   . ALA A 1 231 ? -50.156 -34.018 38.101  1   65.31  ? 401 ALA D N   1 
ATOM   1855 C CA  . ALA A 1 231 ? -49.691 -32.958 38.99   1   59.45  ? 401 ALA D CA  1 
ATOM   1856 C C   . ALA A 1 231 ? -49.483 -33.457 40.423  1   59.79  ? 401 ALA D C   1 
ATOM   1857 O O   . ALA A 1 231 ? -48.466 -33.144 41.051  1   58.03  ? 401 ALA D O   1 
ATOM   1858 C CB  . ALA A 1 231 ? -50.652 -31.807 38.954  1   57.22  ? 401 ALA D CB  1 
ATOM   1859 N N   . PRO A 1 232 ? -50.432 -34.228 41.009  1   60.67  ? 402 PRO D N   1 
ATOM   1860 C CA  . PRO A 1 232 ? -50.232 -34.802 42.345  1   60.07  ? 402 PRO D CA  1 
ATOM   1861 C C   . PRO A 1 232 ? -49.018 -35.726 42.477  1   58.47  ? 402 PRO D C   1 
ATOM   1862 O O   . PRO A 1 232 ? -48.623 -36.067 43.585  1   58.33  ? 402 PRO D O   1 
ATOM   1863 C CB  . PRO A 1 232 ? -51.55  -35.541 42.581  1   62.75  ? 402 PRO D CB  1 
ATOM   1864 C CG  . PRO A 1 232 ? -52.531 -34.806 41.71   1   62.57  ? 402 PRO D CG  1 
ATOM   1865 C CD  . PRO A 1 232 ? -51.747 -34.563 40.439  1   61.02  ? 402 PRO D CD  1 
ATOM   1866 N N   . GLN A 1 233 ? -48.392 -36.072 41.349  1   57.44  ? 403 GLN D N   1 
ATOM   1867 C CA  . GLN A 1 233 ? -47.278 -37.006 41.349  1   58.58  ? 403 GLN D CA  1 
ATOM   1868 C C   . GLN A 1 233 ? -45.989 -36.344 40.863  1   54.89  ? 403 GLN D C   1 
ATOM   1869 O O   . GLN A 1 233 ? -44.968 -37.019 40.763  1   54.18  ? 403 GLN D O   1 
ATOM   1870 C CB  . GLN A 1 233 ? -47.58  -38.261 40.518  1   63.32  ? 403 GLN D CB  1 
ATOM   1871 C CG  . GLN A 1 233 ? -48.627 -39.223 41.091  1   67.9   ? 403 GLN D CG  1 
ATOM   1872 C CD  . GLN A 1 233 ? -50.06  -38.864 40.743  1   70.47  ? 403 GLN D CD  1 
ATOM   1873 O OE1 . GLN A 1 233 ? -50.953 -38.811 41.599  1   72.96  ? 403 GLN D OE1 1 
ATOM   1874 N NE2 . GLN A 1 233 ? -50.311 -38.631 39.462  1   70.15  ? 403 GLN D NE2 1 
ATOM   1875 N N   . HIS A 1 234 ? -46.029 -35.029 40.597  1   52.65  ? 404 HIS D N   1 
ATOM   1876 C CA  . HIS A 1 234 ? -44.852 -34.294 40.152  1   49.04  ? 404 HIS D CA  1 
ATOM   1877 C C   . HIS A 1 234 ? -43.892 -34.137 41.332  1   48.51  ? 404 HIS D C   1 
ATOM   1878 O O   . HIS A 1 234 ? -44.311 -34.119 42.485  1   50.79  ? 404 HIS D O   1 
ATOM   1879 C CB  . HIS A 1 234 ? -45.29  -32.968 39.528  1   47.01  ? 404 HIS D CB  1 
ATOM   1880 C CG  . HIS A 1 234 ? -44.257 -32.292 38.708  1   45.92  ? 404 HIS D CG  1 
ATOM   1881 N ND1 . HIS A 1 234 ? -43.113 -31.74  39.253  1   45.78  ? 404 HIS D ND1 1 
ATOM   1882 C CD2 . HIS A 1 234 ? -44.197 -32.062 37.386  1   45.04  ? 404 HIS D CD2 1 
ATOM   1883 C CE1 . HIS A 1 234 ? -42.371 -31.22  38.283  1   43.77  ? 404 HIS D CE1 1 
ATOM   1884 N NE2 . HIS A 1 234 ? -43.028 -31.394 37.139  1   43.51  ? 404 HIS D NE2 1 
ATOM   1885 N N   . ALA A 1 235 ? -42.593 -34.067 41.044  1   46.9   ? 405 ALA D N   1 
ATOM   1886 C CA  . ALA A 1 235 ? -41.584 -33.946 42.081  1   47.76  ? 405 ALA D CA  1 
ATOM   1887 C C   . ALA A 1 235 ? -41.722 -32.597 42.786  1   49.37  ? 405 ALA D C   1 
ATOM   1888 O O   . ALA A 1 235 ? -41.326 -32.449 43.944  1   50.26  ? 405 ALA D O   1 
ATOM   1889 C CB  . ALA A 1 235 ? -40.218 -34.11  41.459  1   45.57  ? 405 ALA D CB  1 
ATOM   1890 N N   . GLN A 1 236 ? -42.278 -31.622 42.052  1   50.05  ? 406 GLN D N   1 
ATOM   1891 C CA  . GLN A 1 236 ? -42.432 -30.254 42.503  1   49.53  ? 406 GLN D CA  1 
ATOM   1892 C C   . GLN A 1 236 ? -43.898 -30.035 42.858  1   52.66  ? 406 GLN D C   1 
ATOM   1893 O O   . GLN A 1 236 ? -44.774 -30.392 42.074  1   53.6   ? 406 GLN D O   1 
ATOM   1894 C CB  . GLN A 1 236 ? -41.937 -29.337 41.386  1   48.61  ? 406 GLN D CB  1 
ATOM   1895 C CG  . GLN A 1 236 ? -40.506 -28.829 41.541  1   48.79  ? 406 GLN D CG  1 
ATOM   1896 C CD  . GLN A 1 236 ? -39.44  -29.896 41.567  1   52.13  ? 406 GLN D CD  1 
ATOM   1897 O OE1 . GLN A 1 236 ? -39.337 -30.717 40.646  1   56.98  ? 406 GLN D OE1 1 
ATOM   1898 N NE2 . GLN A 1 236 ? -38.622 -29.862 42.613  1   52.97  ? 406 GLN D NE2 1 
ATOM   1899 N N   . GLN A 1 237 ? -44.163 -29.455 44.042  1   55.4   ? 407 GLN D N   1 
ATOM   1900 C CA  . GLN A 1 237 ? -45.497 -29.483 44.628  1   55.88  ? 407 GLN D CA  1 
ATOM   1901 C C   . GLN A 1 237 ? -45.906 -28.151 45.258  1   56.28  ? 407 GLN D C   1 
ATOM   1902 O O   . GLN A 1 237 ? -47.015 -28.07  45.763  1   59.56  ? 407 GLN D O   1 
ATOM   1903 C CB  . GLN A 1 237 ? -45.59  -30.608 45.658  1   54.91  ? 407 GLN D CB  1 
ATOM   1904 C CG  . GLN A 1 237 ? -45.555 -31.996 45.034  1   55.43  ? 407 GLN D CG  1 
ATOM   1905 C CD  . GLN A 1 237 ? -46.819 -32.347 44.277  1   56.55  ? 407 GLN D CD  1 
ATOM   1906 O OE1 . GLN A 1 237 ? -47.934 -32.135 44.766  1   56.69  ? 407 GLN D OE1 1 
ATOM   1907 N NE2 . GLN A 1 237 ? -46.665 -32.891 43.074  1   57.24  ? 407 GLN D NE2 1 
ATOM   1908 N N   . SER A 1 238 ? -45.076 -27.103 45.159  1   53.9   ? 408 SER D N   1 
ATOM   1909 C CA  . SER A 1 238 ? -45.364 -25.819 45.79   1   52.66  ? 408 SER D CA  1 
ATOM   1910 C C   . SER A 1 238 ? -46.574 -25.14  45.158  1   52.9   ? 408 SER D C   1 
ATOM   1911 O O   . SER A 1 238 ? -47.341 -24.488 45.872  1   56.99  ? 408 SER D O   1 
ATOM   1912 C CB  . SER A 1 238 ? -44.177 -24.896 45.787  1   49.79  ? 408 SER D CB  1 
ATOM   1913 O OG  . SER A 1 238 ? -43.081 -25.503 46.446  1   52.53  ? 408 SER D OG  1 
ATOM   1914 N N   . ILE A 1 239 ? -46.736 -25.274 43.832  1   49.72  ? 409 ILE D N   1 
ATOM   1915 C CA  . ILE A 1 239 ? -47.856 -24.64  43.156  1   49.27  ? 409 ILE D CA  1 
ATOM   1916 C C   . ILE A 1 239 ? -49.172 -25.18  43.716  1   52.91  ? 409 ILE D C   1 
ATOM   1917 O O   . ILE A 1 239 ? -50.035 -24.405 44.137  1   57.47  ? 409 ILE D O   1 
ATOM   1918 C CB  . ILE A 1 239 ? -47.749 -24.74  41.625  1   46.88  ? 409 ILE D CB  1 
ATOM   1919 C CG1 . ILE A 1 239 ? -46.458 -24.083 41.116  1   43.92  ? 409 ILE D CG1 1 
ATOM   1920 C CG2 . ILE A 1 239 ? -48.987 -24.13  40.959  1   46.53  ? 409 ILE D CG2 1 
ATOM   1921 C CD1 . ILE A 1 239 ? -46.167 -24.26  39.641  1   40.4   ? 409 ILE D CD1 1 
ATOM   1922 N N   . ARG A 1 240 ? -49.297 -26.509 43.753  1   53.44  ? 410 ARG D N   1 
ATOM   1923 C CA  . ARG A 1 240 ? -50.463 -27.168 44.327  1   56.85  ? 410 ARG D CA  1 
ATOM   1924 C C   . ARG A 1 240 ? -50.667 -26.774 45.793  1   57.73  ? 410 ARG D C   1 
ATOM   1925 O O   . ARG A 1 240 ? -51.781 -26.446 46.185  1   59.48  ? 410 ARG D O   1 
ATOM   1926 C CB  . ARG A 1 240 ? -50.337 -28.691 44.189  1   58.96  ? 410 ARG D CB  1 
ATOM   1927 C CG  . ARG A 1 240 ? -50.458 -29.181 42.753  1   58.5   ? 410 ARG D CG  1 
ATOM   1928 C CD  . ARG A 1 240 ? -50.519 -30.691 42.659  1   59.84  ? 410 ARG D CD  1 
ATOM   1929 N NE  . ARG A 1 240 ? -51.767 -31.251 43.187  1   61.71  ? 410 ARG D NE  1 
ATOM   1930 C CZ  . ARG A 1 240 ? -51.877 -31.976 44.303  1   63.53  ? 410 ARG D CZ  1 
ATOM   1931 N NH1 . ARG A 1 240 ? -53.056 -32.142 44.869  1   65.86  ? 410 ARG D NH1 1 
ATOM   1932 N NH2 . ARG A 1 240 ? -50.814 -32.464 44.907  1   62.51  ? 410 ARG D NH2 1 
ATOM   1933 N N   . GLU A 1 241 ? -49.596 -26.818 46.596  1   56.7   ? 411 GLU D N   1 
ATOM   1934 C CA  . GLU A 1 241 ? -49.636 -26.401 47.989  1   57.48  ? 411 GLU D CA  1 
ATOM   1935 C C   . GLU A 1 241 ? -50.218 -24.995 48.08   1   56.42  ? 411 GLU D C   1 
ATOM   1936 O O   . GLU A 1 241 ? -51.029 -24.731 48.963  1   59.74  ? 411 GLU D O   1 
ATOM   1937 C CB  . GLU A 1 241 ? -48.262 -26.394 48.666  1   57.62  ? 411 GLU D CB  1 
ATOM   1938 C CG  . GLU A 1 241 ? -47.568 -27.754 48.732  1   62.86  ? 411 GLU D CG  1 
ATOM   1939 C CD  . GLU A 1 241 ? -48.414 -28.903 49.286  1   71.79  ? 411 GLU D CD  1 
ATOM   1940 O OE1 . GLU A 1 241 ? -49.369 -28.661 50.078  1   74.15  ? 411 GLU D OE1 1 
ATOM   1941 O OE2 . GLU A 1 241 ? -48.11  -30.074 48.913  1   74.44  ? 411 GLU D OE2 1 
ATOM   1942 N N   . LYS A 1 242 ? -49.806 -24.115 47.16   1   52.49  ? 412 LYS D N   1 
ATOM   1943 C CA  . LYS A 1 242 ? -50.257 -22.731 47.121  1   52.57  ? 412 LYS D CA  1 
ATOM   1944 C C   . LYS A 1 242 ? -51.754 -22.633 46.826  1   56.15  ? 412 LYS D C   1 
ATOM   1945 O O   . LYS A 1 242 ? -52.477 -21.903 47.508  1   58.89  ? 412 LYS D O   1 
ATOM   1946 C CB  . LYS A 1 242 ? -49.46  -21.986 46.048  1   48.04  ? 412 LYS D CB  1 
ATOM   1947 C CG  . LYS A 1 242 ? -49.964 -20.603 45.662  1   45.13  ? 412 LYS D CG  1 
ATOM   1948 C CD  . LYS A 1 242 ? -49.218 -20.166 44.406  1   41.1   ? 412 LYS D CD  1 
ATOM   1949 C CE  . LYS A 1 242 ? -49.09  -18.679 44.246  1   37.86  ? 412 LYS D CE  1 
ATOM   1950 N NZ  . LYS A 1 242 ? -47.993 -18.355 43.341  1   34.64  ? 412 LYS D NZ  1 
ATOM   1951 N N   . TYR A 1 243 ? -52.218 -23.366 45.805  1   57.17  ? 413 TYR D N   1 
ATOM   1952 C CA  . TYR A 1 243 ? -53.594 -23.223 45.353  1   60.74  ? 413 TYR D CA  1 
ATOM   1953 C C   . TYR A 1 243 ? -54.543 -24.169 46.106  1   65.32  ? 413 TYR D C   1 
ATOM   1954 O O   . TYR A 1 243 ? -55.664 -24.424 45.645  1   65.37  ? 413 TYR D O   1 
ATOM   1955 C CB  . TYR A 1 243 ? -53.644 -23.339 43.829  1   58.24  ? 413 TYR D CB  1 
ATOM   1956 C CG  . TYR A 1 243 ? -53.071 -22.152 43.074  1   57.15  ? 413 TYR D CG  1 
ATOM   1957 C CD1 . TYR A 1 243 ? -53.871 -21.062 42.757  1   57.2   ? 413 TYR D CD1 1 
ATOM   1958 C CD2 . TYR A 1 243 ? -51.744 -22.134 42.648  1   56.18  ? 413 TYR D CD2 1 
ATOM   1959 C CE1 . TYR A 1 243 ? -53.359 -19.982 42.049  1   55.85  ? 413 TYR D CE1 1 
ATOM   1960 C CE2 . TYR A 1 243 ? -51.231 -21.065 41.93   1   52.86  ? 413 TYR D CE2 1 
ATOM   1961 C CZ  . TYR A 1 243 ? -52.037 -19.98  41.641  1   53.11  ? 413 TYR D CZ  1 
ATOM   1962 O OH  . TYR A 1 243 ? -51.529 -18.913 40.955  1   53.17  ? 413 TYR D OH  1 
ATOM   1963 N N   . LYS A 1 244 ? -54.111 -24.66  47.277  1   66.95  ? 414 LYS D N   1 
ATOM   1964 C CA  . LYS A 1 244 ? -55.002 -25.378 48.178  1   71.7   ? 414 LYS D CA  1 
ATOM   1965 C C   . LYS A 1 244 ? -55.632 -24.353 49.108  1   73.86  ? 414 LYS D C   1 
ATOM   1966 O O   . LYS A 1 244 ? -56.767 -24.525 49.55   1   75.3   ? 414 LYS D O   1 
ATOM   1967 C CB  . LYS A 1 244 ? -54.287 -26.425 49.043  1   72.6   ? 414 LYS D CB  1 
ATOM   1968 C CG  . LYS A 1 244 ? -53.703 -27.636 48.34   1   72.64  ? 414 LYS D CG  1 
ATOM   1969 C CD  . LYS A 1 244 ? -53.145 -28.693 49.278  1   72.49  ? 414 LYS D CD  1 
ATOM   1970 C CE  . LYS A 1 244 ? -52.083 -29.565 48.651  1   71.56  ? 414 LYS D CE  1 
ATOM   1971 N NZ  . LYS A 1 244 ? -52.611 -30.437 47.58   1   71.67  ? 414 LYS D NZ  1 
ATOM   1972 N N   . ASN A 1 245 ? -54.85  -23.301 49.394  1   74.39  ? 415 ASN D N   1 
ATOM   1973 C CA  . ASN A 1 245 ? -55.23  -22.204 50.268  1   76.95  ? 415 ASN D CA  1 
ATOM   1974 C C   . ASN A 1 245 ? -56.542 -21.588 49.768  1   77.13  ? 415 ASN D C   1 
ATOM   1975 O O   . ASN A 1 245 ? -56.896 -21.746 48.6    1   75.44  ? 415 ASN D O   1 
ATOM   1976 C CB  . ASN A 1 245 ? -54.049 -21.247 50.422  1   76.3   ? 415 ASN D CB  1 
ATOM   1977 C CG  . ASN A 1 245 ? -54.366 -20.006 51.23   1   85.13  ? 415 ASN D CG  1 
ATOM   1978 O OD1 . ASN A 1 245 ? -54.032 -18.887 50.815  1   80.8   ? 415 ASN D OD1 1 
ATOM   1979 N ND2 . ASN A 1 245 ? -55.002 -20.173 52.386  1   95.63  ? 415 ASN D ND2 1 
ATOM   1980 N N   . SER A 1 246 ? -57.237 -20.858 50.656  1   78.47  ? 416 SER D N   1 
ATOM   1981 C CA  . SER A 1 246 ? -58.566 -20.325 50.384  1   79.38  ? 416 SER D CA  1 
ATOM   1982 C C   . SER A 1 246 ? -58.519 -19.02  49.582  1   72.57  ? 416 SER D C   1 
ATOM   1983 O O   . SER A 1 246 ? -59.526 -18.614 49.005  1   72.96  ? 416 SER D O   1 
ATOM   1984 C CB  . SER A 1 246 ? -59.329 -20.143 51.66   1   84.31  ? 416 SER D CB  1 
ATOM   1985 O OG  . SER A 1 246 ? -58.579 -19.281 52.501  1   89.25  ? 416 SER D OG  1 
ATOM   1986 N N   . LYS A 1 247 ? -57.366 -18.348 49.575  1   65.69  ? 417 LYS D N   1 
ATOM   1987 C CA  . LYS A 1 247 ? -57.183 -17.199 48.708  1   63     ? 417 LYS D CA  1 
ATOM   1988 C C   . LYS A 1 247 ? -57.445 -17.594 47.259  1   61.91  ? 417 LYS D C   1 
ATOM   1989 O O   . LYS A 1 247 ? -57.842 -16.757 46.448  1   59.23  ? 417 LYS D O   1 
ATOM   1990 C CB  . LYS A 1 247 ? -55.768 -16.646 48.871  1   62.4   ? 417 LYS D CB  1 
ATOM   1991 C CG  . LYS A 1 247 ? -55.478 -15.348 48.124  1   63.14  ? 417 LYS D CG  1 
ATOM   1992 C CD  . LYS A 1 247 ? -53.993 -15.074 47.9    1   64.31  ? 417 LYS D CD  1 
ATOM   1993 C CE  . LYS A 1 247 ? -53.17  -15.108 49.164  1   71.64  ? 417 LYS D CE  1 
ATOM   1994 N NZ  . LYS A 1 247 ? -51.762 -14.714 49.007  1   77.7   ? 417 LYS D NZ  1 
ATOM   1995 N N   . TYR A 1 248 ? -57.222 -18.879 46.962  1   63.54  ? 418 TYR D N   1 
ATOM   1996 C CA  . TYR A 1 248 ? -57.335 -19.412 45.615  1   64.18  ? 418 TYR D CA  1 
ATOM   1997 C C   . TYR A 1 248 ? -58.502 -20.396 45.53   1   69.53  ? 418 TYR D C   1 
ATOM   1998 O O   . TYR A 1 248 ? -58.72  -20.997 44.474  1   71.7   ? 418 TYR D O   1 
ATOM   1999 C CB  . TYR A 1 248 ? -56.004 -20.043 45.189  1   60.6   ? 418 TYR D CB  1 
ATOM   2000 C CG  . TYR A 1 248 ? -54.806 -19.106 45.274  1   58.85  ? 418 TYR D CG  1 
ATOM   2001 C CD1 . TYR A 1 248 ? -54.644 -18.06  44.368  1   56.05  ? 418 TYR D CD1 1 
ATOM   2002 C CD2 . TYR A 1 248 ? -53.84  -19.26  46.27   1   60.02  ? 418 TYR D CD2 1 
ATOM   2003 C CE1 . TYR A 1 248 ? -53.55  -17.212 44.436  1   53.16  ? 418 TYR D CE1 1 
ATOM   2004 C CE2 . TYR A 1 248 ? -52.754 -18.398 46.372  1   55.66  ? 418 TYR D CE2 1 
ATOM   2005 C CZ  . TYR A 1 248 ? -52.606 -17.379 45.442  1   54.52  ? 418 TYR D CZ  1 
ATOM   2006 O OH  . TYR A 1 248 ? -51.536 -16.534 45.528  1   52.81  ? 418 TYR D OH  1 
ATOM   2007 N N   . HIS A 1 249 ? -59.248 -20.563 46.637  1   71.81  ? 419 HIS D N   1 
ATOM   2008 C CA  . HIS A 1 249 ? -60.477 -21.355 46.665  1   72.97  ? 419 HIS D CA  1 
ATOM   2009 C C   . HIS A 1 249 ? -60.2   -22.848 46.489  1   72.92  ? 419 HIS D C   1 
ATOM   2010 O O   . HIS A 1 249 ? -61.078 -23.572 46.021  1   75.29  ? 419 HIS D O   1 
ATOM   2011 C CB  . HIS A 1 249 ? -61.484 -20.836 45.625  1   72.59  ? 419 HIS D CB  1 
ATOM   2012 C CG  . HIS A 1 249 ? -61.565 -19.343 45.591  1   72.47  ? 419 HIS D CG  1 
ATOM   2013 N ND1 . HIS A 1 249 ? -60.805 -18.559 44.744  1   69.39  ? 419 HIS D ND1 1 
ATOM   2014 C CD2 . HIS A 1 249 ? -62.289 -18.491 46.334  1   73.19  ? 419 HIS D CD2 1 
ATOM   2015 C CE1 . HIS A 1 249 ? -61.076 -17.283 44.967  1   67.43  ? 419 HIS D CE1 1 
ATOM   2016 N NE2 . HIS A 1 249 ? -61.98  -17.219 45.924  1   70.6   ? 419 HIS D NE2 1 
ATOM   2017 N N   . GLY A 1 250 ? -58.985 -23.29  46.857  1   72.27  ? 420 GLY D N   1 
ATOM   2018 C CA  . GLY A 1 250 ? -58.58  -24.692 46.816  1   74.96  ? 420 GLY D CA  1 
ATOM   2019 C C   . GLY A 1 250 ? -58.884 -25.377 45.479  1   75.24  ? 420 GLY D C   1 
ATOM   2020 O O   . GLY A 1 250 ? -59.541 -26.422 45.424  1   78.4   ? 420 GLY D O   1 
ATOM   2021 N N   . VAL A 1 251 ? -58.399 -24.775 44.391  1   70.52  ? 421 VAL D N   1 
ATOM   2022 C CA  . VAL A 1 251 ? -58.657 -25.282 43.052  1   68.27  ? 421 VAL D CA  1 
ATOM   2023 C C   . VAL A 1 251 ? -57.656 -26.399 42.729  1   68.03  ? 421 VAL D C   1 
ATOM   2024 O O   . VAL A 1 251 ? -57.851 -27.183 41.791  1   70.43  ? 421 VAL D O   1 
ATOM   2025 C CB  . VAL A 1 251 ? -58.59  -24.109 42.053  1   64.48  ? 421 VAL D CB  1 
ATOM   2026 C CG1 . VAL A 1 251 ? -59.852 -23.245 42.104  1   64.93  ? 421 VAL D CG1 1 
ATOM   2027 C CG2 . VAL A 1 251 ? -57.341 -23.265 42.299  1   62.13  ? 421 VAL D CG2 1 
ATOM   2028 N N   . SER A 1 252 ? -56.578 -26.48  43.523  1   65.43  ? 422 SER D N   1 
ATOM   2029 C CA  . SER A 1 252 ? -55.628 -27.578 43.421  1   64.34  ? 422 SER D CA  1 
ATOM   2030 C C   . SER A 1 252 ? -56.246 -28.872 43.956  1   65.94  ? 422 SER D C   1 
ATOM   2031 O O   . SER A 1 252 ? -55.644 -29.933 43.829  1   65.53  ? 422 SER D O   1 
ATOM   2032 C CB  . SER A 1 252 ? -54.366 -27.272 44.18   1   62.49  ? 422 SER D CB  1 
ATOM   2033 O OG  . SER A 1 252 ? -54.588 -27.392 45.578  1   66.36  ? 422 SER D OG  1 
ATOM   2034 N N   . LEU A 1 253 ? -57.416 -28.759 44.599  1   66.96  ? 423 LEU D N   1 
ATOM   2035 C CA  . LEU A 1 253 ? -58.082 -29.874 45.25   1   68.42  ? 423 LEU D CA  1 
ATOM   2036 C C   . LEU A 1 253 ? -59.229 -30.362 44.372  1   70.82  ? 423 LEU D C   1 
ATOM   2037 O O   . LEU A 1 253 ? -59.707 -31.478 44.534  1   73.39  ? 423 LEU D O   1 
ATOM   2038 C CB  . LEU A 1 253 ? -58.536 -29.446 46.649  1   67.58  ? 423 LEU D CB  1 
ATOM   2039 C CG  . LEU A 1 253 ? -57.427 -29.076 47.645  1   64.69  ? 423 LEU D CG  1 
ATOM   2040 C CD1 . LEU A 1 253 ? -57.99  -28.482 48.93   1   64.91  ? 423 LEU D CD1 1 
ATOM   2041 C CD2 . LEU A 1 253 ? -56.52  -30.265 47.956  1   64.6   ? 423 LEU D CD2 1 
ATOM   2042 N N   . LEU A 1 254 ? -59.631 -29.535 43.404  1   71.76  ? 424 LEU D N   1 
ATOM   2043 C CA  . LEU A 1 254 ? -60.619 -29.953 42.421  1   75.57  ? 424 LEU D CA  1 
ATOM   2044 C C   . LEU A 1 254 ? -59.984 -31.029 41.543  1   78.01  ? 424 LEU D C   1 
ATOM   2045 O O   . LEU A 1 254 ? -58.758 -31.045 41.421  1   77.65  ? 424 LEU D O   1 
ATOM   2046 C CB  . LEU A 1 254 ? -61.062 -28.723 41.63   1   71.94  ? 424 LEU D CB  1 
ATOM   2047 C CG  . LEU A 1 254 ? -61.612 -27.573 42.486  1   71.96  ? 424 LEU D CG  1 
ATOM   2048 C CD1 . LEU A 1 254 ? -62.106 -26.415 41.642  1   71.09  ? 424 LEU D CD1 1 
ATOM   2049 C CD2 . LEU A 1 254 ? -62.725 -28.024 43.424  1   73.04  ? 424 LEU D CD2 1 
ATOM   2050 N N   . ASN A 1 255 ? -60.809 -31.901 40.939  1   80.33  ? 425 ASN D N   1 
ATOM   2051 C CA  . ASN A 1 255 ? -60.32  -33.037 40.17   1   80.67  ? 425 ASN D CA  1 
ATOM   2052 C C   . ASN A 1 255 ? -60.276 -32.725 38.675  1   77.73  ? 425 ASN D C   1 
ATOM   2053 O O   . ASN A 1 255 ? -61.3   -32.38  38.089  1   77.18  ? 425 ASN D O   1 
ATOM   2054 C CB  . ASN A 1 255 ? -61.159 -34.279 40.432  1   88.68  ? 425 ASN D CB  1 
ATOM   2055 C CG  . ASN A 1 255 ? -60.998 -34.801 41.842  1   94.77  ? 425 ASN D CG  1 
ATOM   2056 O OD1 . ASN A 1 255 ? -61.795 -34.458 42.725  1   100.76 ? 425 ASN D OD1 1 
ATOM   2057 N ND2 . ASN A 1 255 ? -59.981 -35.62  42.074  1   92.1   ? 425 ASN D ND2 1 
ATOM   2058 N N   . PRO A 1 256 ? -59.097 -32.866 38.014  1   76.11  ? 426 PRO D N   1 
ATOM   2059 C CA  . PRO A 1 256 ? -58.974 -32.655 36.568  1   74.61  ? 426 PRO D CA  1 
ATOM   2060 C C   . PRO A 1 256 ? -60.09  -33.4   35.846  1   77.57  ? 426 PRO D C   1 
ATOM   2061 O O   . PRO A 1 256 ? -60.401 -34.538 36.198  1   82.58  ? 426 PRO D O   1 
ATOM   2062 C CB  . PRO A 1 256 ? -57.601 -33.262 36.194  1   72.79  ? 426 PRO D CB  1 
ATOM   2063 C CG  . PRO A 1 256 ? -57.127 -33.991 37.451  1   74.4   ? 426 PRO D CG  1 
ATOM   2064 C CD  . PRO A 1 256 ? -57.817 -33.277 38.618  1   75.46  ? 426 PRO D CD  1 
ATOM   2065 N N   . PRO A 1 257 ? -60.7   -32.821 34.79   1   76.09  ? 427 PRO D N   1 
ATOM   2066 C CA  . PRO A 1 257 ? -61.622 -33.588 33.948  1   80.31  ? 427 PRO D CA  1 
ATOM   2067 C C   . PRO A 1 257 ? -60.785 -34.72  33.354  1   83.79  ? 427 PRO D C   1 
ATOM   2068 O O   . PRO A 1 257 ? -59.553 -34.661 33.397  1   83.69  ? 427 PRO D O   1 
ATOM   2069 C CB  . PRO A 1 257 ? -62.095 -32.58  32.906  1   78.18  ? 427 PRO D CB  1 
ATOM   2070 C CG  . PRO A 1 257 ? -60.995 -31.53  32.888  1   74.48  ? 427 PRO D CG  1 
ATOM   2071 C CD  . PRO A 1 257 ? -60.481 -31.45  34.314  1   72.24  ? 427 PRO D CD  1 
ATOM   2072 N N   . GLU A 1 258 ? -61.447 -35.767 32.853  1   90.9   ? 428 GLU D N   1 
ATOM   2073 C CA  . GLU A 1 258 ? -60.732 -36.93  32.338  1   93.97  ? 428 GLU D CA  1 
ATOM   2074 C C   . GLU A 1 258 ? -60.536 -36.8   30.83   1   92.42  ? 428 GLU D C   1 
ATOM   2075 O O   . GLU A 1 258 ? -59.529 -37.255 30.284  1   88.54  ? 428 GLU D O   1 
ATOM   2076 C CB  . GLU A 1 258 ? -61.499 -38.228 32.575  1   98.6   ? 428 GLU D CB  1 
ATOM   2077 C CG  . GLU A 1 258 ? -61.867 -38.478 34.033  1   103.54 ? 428 GLU D CG  1 
ATOM   2078 C CD  . GLU A 1 258 ? -62.58  -39.818 34.196  1   115.24 ? 428 GLU D CD  1 
ATOM   2079 O OE1 . GLU A 1 258 ? -63.066 -40.419 33.198  1   117.22 ? 428 GLU D OE1 1 
ATOM   2080 O OE2 . GLU A 1 258 ? -62.625 -40.29  35.352  1   121.81 ? 428 GLU D OE2 1 
ATOM   2081 N N   . THR A 1 259 ? -61.583 -36.272 30.193  1   93.21  ? 429 THR D N   1 
ATOM   2082 C CA  . THR A 1 259 ? -61.568 -36.111 28.731  1   92.95  ? 429 THR D CA  1 
ATOM   2083 C C   . THR A 1 259 ? -62.016 -34.714 28.434  1   91.51  ? 429 THR D C   1 
ATOM   2084 O O   . THR A 1 259 ? -62.872 -34.199 29.176  1   92.12  ? 429 THR D O   1 
ATOM   2085 C CB  . THR A 1 259 ? -62.511 -37.122 28.083  1   95.43  ? 429 THR D CB  1 
ATOM   2086 O OG1 . THR A 1 259 ? -63.808 -36.748 28.535  1   99.03  ? 429 THR D OG1 1 
ATOM   2087 C CG2 . THR A 1 259 ? -62.223 -38.556 28.488  1   94.55  ? 429 THR D CG2 1 
ATOM   2088 N N   . LEU A 1 260 ? -61.465 -34.123 27.381  1   90.45  ? 430 LEU D N   1 
ATOM   2089 C CA  . LEU A 1 260 ? -61.794 -32.722 27.041  1   91.39  ? 430 LEU D CA  1 
ATOM   2090 C C   . LEU A 1 260 ? -62.842 -32.739 25.933  1   95.87  ? 430 LEU D C   1 
ATOM   2091 O O   . LEU A 1 260 ? -63.329 -31.655 25.571  1   96.65  ? 430 LEU D O   1 
ATOM   2092 C CB  . LEU A 1 260 ? -60.507 -32.023 26.616  1   87.54  ? 430 LEU D CB  1 
ATOM   2093 C CG  . LEU A 1 260 ? -59.371 -32.042 27.643  1   84.45  ? 430 LEU D CG  1 
ATOM   2094 C CD1 . LEU A 1 260 ? -58.275 -31.071 27.247  1   79.8   ? 430 LEU D CD1 1 
ATOM   2095 C CD2 . LEU A 1 260 ? -59.9   -31.719 29.028  1   84.26  ? 430 LEU D CD2 1 
ATOM   2096 N N   . ASN A 1 261 ? -63.159 -33.931 25.432  1   100.49 ? 431 ASN D N   1 
ATOM   2097 C CA  . ASN A 1 261 ? -64.19  -34.084 24.37   1   105.1  ? 431 ASN D CA  1 
ATOM   2098 C C   . ASN A 1 261 ? -63.843 -33.131 23.224  1   102.8  ? 431 ASN D C   1 
ATOM   2099 O O   . ASN A 1 261 ? -64.584 -32.159 22.999  1   102.1  ? 431 ASN D O   1 
ATOM   2100 C CB  . ASN A 1 261 ? -65.593 -33.972 24.956  1   110.13 ? 431 ASN D CB  1 
ATOM   2101 C CG  . ASN A 1 261 ? -65.738 -34.795 26.212  1   112.17 ? 431 ASN D CG  1 
ATOM   2102 O OD1 . ASN A 1 261 ? -66.139 -34.271 27.255  1   114.37 ? 431 ASN D OD1 1 
ATOM   2103 N ND2 . ASN A 1 261 ? -65.414 -36.077 26.135  1   110.78 ? 431 ASN D ND2 1 
ATOM   2104 N N   . VAL A 1 262 ? -62.755 -33.432 22.52   1   102.32 ? 432 VAL D N   1 
ATOM   2105 C CA  . VAL A 1 262 ? -62.309 -32.582 21.383  1   99.08  ? 432 VAL D CA  1 
ATOM   2106 C C   . VAL A 1 262 ? -62.79  -33.223 20.075  1   101.08 ? 432 VAL D C   1 
ATOM   2107 O O   . VAL A 1 262 ? -64.008 -33.131 19.807  1   101.71 ? 432 VAL D O   1 
ATOM   2108 C CB  . VAL A 1 262 ? -60.777 -32.466 21.422  1   94.96  ? 432 VAL D CB  1 
ATOM   2109 C CG1 . VAL A 1 262 ? -60.241 -31.709 20.213  1   87.41  ? 432 VAL D CG1 1 
ATOM   2110 C CG2 . VAL A 1 262 ? -60.3   -31.809 22.71   1   94.28  ? 432 VAL D CG2 1 
ATOM   2111 N N   . PRO B 2 2   ? -22.221 -7.765  26.606  1   97.71  ? -2  PRO A N   1 
ATOM   2112 C CA  . PRO B 2 2   ? -22.616 -8.363  27.883  1   95.76  ? -2  PRO A CA  1 
ATOM   2113 C C   . PRO B 2 2   ? -21.623 -8.265  29.051  1   88.66  ? -2  PRO A C   1 
ATOM   2114 O O   . PRO B 2 2   ? -22.036 -8.27   30.213  1   84.69  ? -2  PRO A O   1 
ATOM   2115 C CB  . PRO B 2 2   ? -22.918 -9.84   27.489  1   90.82  ? -2  PRO A CB  1 
ATOM   2116 C CG  . PRO B 2 2   ? -23.429 -9.748  26.063  1   88.78  ? -2  PRO A CG  1 
ATOM   2117 C CD  . PRO B 2 2   ? -22.863 -8.449  25.484  1   89.43  ? -2  PRO A CD  1 
ATOM   2118 N N   . GLY B 2 3   ? -20.322 -8.125  28.732  1   82.44  ? -1  GLY A N   1 
ATOM   2119 C CA  . GLY B 2 3   ? -19.207 -8.488  29.6    1   83.12  ? -1  GLY A CA  1 
ATOM   2120 C C   . GLY B 2 3   ? -18.609 -7.335  30.413  1   90.8   ? -1  GLY A C   1 
ATOM   2121 O O   . GLY B 2 3   ? -18.817 -6.164  30.113  1   92.22  ? -1  GLY A O   1 
ATOM   2122 N N   . SER B 2 4   ? -17.84  -7.698  31.452  1   91.99  ? 0   SER A N   1 
ATOM   2123 C CA  . SER B 2 4   ? -17.111 -6.805  32.344  1   84.65  ? 0   SER A CA  1 
ATOM   2124 C C   . SER B 2 4   ? -15.89  -7.576  32.868  1   81.01  ? 0   SER A C   1 
ATOM   2125 O O   . SER B 2 4   ? -16.081 -8.641  33.461  1   87.43  ? 0   SER A O   1 
ATOM   2126 C CB  . SER B 2 4   ? -18.066 -6.382  33.47   1   87.15  ? 0   SER A CB  1 
ATOM   2127 O OG  . SER B 2 4   ? -17.459 -5.631  34.52   1   86.36  ? 0   SER A OG  1 
ATOM   2128 N N   . MET B 2 5   ? -14.648 -7.088  32.633  1   71.51  ? 1   MET A N   1 
ATOM   2129 C CA  . MET B 2 5   ? -13.434 -7.85   32.967  1   63.01  ? 1   MET A CA  1 
ATOM   2130 C C   . MET B 2 5   ? -13.31  -8.125  34.47   1   61.97  ? 1   MET A C   1 
ATOM   2131 O O   . MET B 2 5   ? -12.518 -8.964  34.889  1   60.31  ? 1   MET A O   1 
ATOM   2132 C CB  . MET B 2 5   ? -12.13  -7.16   32.546  1   59.03  ? 1   MET A CB  1 
ATOM   2133 C CG  . MET B 2 5   ? -11.921 -7.07   31.072  1   56.14  ? 1   MET A CG  1 
ATOM   2134 S SD  . MET B 2 5   ? -12.371 -8.555  30.149  1   53.06  ? 1   MET A SD  1 
ATOM   2135 C CE  . MET B 2 5   ? -11.266 -9.828  30.755  1   51.6   ? 1   MET A CE  1 
ATOM   2136 N N   . GLU B 2 6   ? -14.067 -7.38   35.276  1   62.4   ? 2   GLU A N   1 
ATOM   2137 C CA  . GLU B 2 6   ? -14.036 -7.556  36.709  1   64.49  ? 2   GLU A CA  1 
ATOM   2138 C C   . GLU B 2 6   ? -14.574 -8.928  37.114  1   61.81  ? 2   GLU A C   1 
ATOM   2139 O O   . GLU B 2 6   ? -14.127 -9.474  38.12   1   63.91  ? 2   GLU A O   1 
ATOM   2140 C CB  . GLU B 2 6   ? -14.818 -6.453  37.414  1   69.71  ? 2   GLU A CB  1 
ATOM   2141 C CG  . GLU B 2 6   ? -14.759 -6.61   38.933  1   75.27  ? 2   GLU A CG  1 
ATOM   2142 C CD  . GLU B 2 6   ? -13.411 -6.587  39.654  1   79.26  ? 2   GLU A CD  1 
ATOM   2143 O OE1 . GLU B 2 6   ? -13.454 -6.935  40.852  1   83.23  ? 2   GLU A OE1 1 
ATOM   2144 O OE2 . GLU B 2 6   ? -12.34  -6.229  39.097  1   80.52  ? 2   GLU A OE2 1 
ATOM   2145 N N   . ASN B 2 7   ? -15.545 -9.468  36.361  1   57.49  ? 3   ASN A N   1 
ATOM   2146 C CA  . ASN B 2 7   ? -16.177 -10.739 36.706  1   55.4   ? 3   ASN A CA  1 
ATOM   2147 C C   . ASN B 2 7   ? -15.396 -11.931 36.166  1   53.36  ? 3   ASN A C   1 
ATOM   2148 O O   . ASN B 2 7   ? -15.898 -13.053 36.211  1   50.52  ? 3   ASN A O   1 
ATOM   2149 C CB  . ASN B 2 7   ? -17.563 -10.933 36.101  1   54.09  ? 3   ASN A CB  1 
ATOM   2150 C CG  . ASN B 2 7   ? -18.502 -9.811  36.451  1   58.24  ? 3   ASN A CG  1 
ATOM   2151 O OD1 . ASN B 2 7   ? -18.483 -9.312  37.6    1   60.52  ? 3   ASN A OD1 1 
ATOM   2152 N ND2 . ASN B 2 7   ? -19.291 -9.415  35.455  1   55.73  ? 3   ASN A ND2 1 
ATOM   2153 N N   . PHE B 2 8   ? -14.2   -11.667 35.625  1   53.83  ? 4   PHE A N   1 
ATOM   2154 C CA  . PHE B 2 8   ? -13.322 -12.72  35.145  1   49.76  ? 4   PHE A CA  1 
ATOM   2155 C C   . PHE B 2 8   ? -12.134 -12.857 36.088  1   53.08  ? 4   PHE A C   1 
ATOM   2156 O O   . PHE B 2 8   ? -11.547 -11.879 36.545  1   58.14  ? 4   PHE A O   1 
ATOM   2157 C CB  . PHE B 2 8   ? -12.938 -12.439 33.702  1   45.55  ? 4   PHE A CB  1 
ATOM   2158 C CG  . PHE B 2 8   ? -14.088 -12.686 32.749  1   44.44  ? 4   PHE A CG  1 
ATOM   2159 C CD1 . PHE B 2 8   ? -14.619 -13.962 32.606  1   43.75  ? 4   PHE A CD1 1 
ATOM   2160 C CD2 . PHE B 2 8   ? -14.617 -11.661 31.968  1   45.92  ? 4   PHE A CD2 1 
ATOM   2161 C CE1 . PHE B 2 8   ? -15.64  -14.217 31.698  1   42.52  ? 4   PHE A CE1 1 
ATOM   2162 C CE2 . PHE B 2 8   ? -15.639 -11.916 31.061  1   44.27  ? 4   PHE A CE2 1 
ATOM   2163 C CZ  . PHE B 2 8   ? -16.139 -13.193 30.916  1   43.21  ? 4   PHE A CZ  1 
ATOM   2164 N N   . GLN B 2 9   ? -11.808 -14.11  36.367  1   52.11  ? 5   GLN A N   1 
ATOM   2165 C CA  . GLN B 2 9   ? -10.773 -14.499 37.301  1   53.82  ? 5   GLN A CA  1 
ATOM   2166 C C   . GLN B 2 9   ? -9.729  -15.257 36.484  1   53.14  ? 5   GLN A C   1 
ATOM   2167 O O   . GLN B 2 9   ? -10.06  -16.251 35.831  1   50.71  ? 5   GLN A O   1 
ATOM   2168 C CB  . GLN B 2 9   ? -11.539 -15.382 38.283  1   54.24  ? 5   GLN A CB  1 
ATOM   2169 C CG  . GLN B 2 9   ? -10.721 -16.47  38.955  1   57.72  ? 5   GLN A CG  1 
ATOM   2170 C CD  . GLN B 2 9   ? -9.878  -15.862 40.032  1   64.88  ? 5   GLN A CD  1 
ATOM   2171 O OE1 . GLN B 2 9   ? -10.389 -15.4   41.066  1   68.62  ? 5   GLN A OE1 1 
ATOM   2172 N NE2 . GLN B 2 9   ? -8.586  -15.812 39.747  1   68.35  ? 5   GLN A NE2 1 
ATOM   2173 N N   . LYS B 2 10  ? -8.493  -14.744 36.458  1   54.3   ? 6   LYS A N   1 
ATOM   2174 C CA  . LYS B 2 10  ? -7.453  -15.379 35.662  1   54.16  ? 6   LYS A CA  1 
ATOM   2175 C C   . LYS B 2 10  ? -6.991  -16.634 36.381  1   54     ? 6   LYS A C   1 
ATOM   2176 O O   . LYS B 2 10  ? -6.899  -16.65  37.611  1   57.1   ? 6   LYS A O   1 
ATOM   2177 C CB  . LYS B 2 10  ? -6.189  -14.547 35.435  1   57.92  ? 6   LYS A CB  1 
ATOM   2178 C CG  . LYS B 2 10  ? -6.151  -13.665 34.2    1   59.31  ? 6   LYS A CG  1 
ATOM   2179 C CD  . LYS B 2 10  ? -5.17   -12.495 34.334  1   64.6   ? 6   LYS A CD  1 
ATOM   2180 C CE  . LYS B 2 10  ? -3.708  -12.809 34.16   1   64.67  ? 6   LYS A CE  1 
ATOM   2181 N NZ  . LYS B 2 10  ? -2.84   -11.761 34.702  1   67.22  ? 6   LYS A NZ  1 
ATOM   2182 N N   . VAL B 2 11  ? -6.694  -17.657 35.58   1   50.6   ? 7   VAL A N   1 
ATOM   2183 C CA  . VAL B 2 11  ? -6.358  -18.969 36.089  1   51.68  ? 7   VAL A CA  1 
ATOM   2184 C C   . VAL B 2 11  ? -4.916  -19.289 35.696  1   54.41  ? 7   VAL A C   1 
ATOM   2185 O O   . VAL B 2 11  ? -4.092  -19.552 36.565  1   61.39  ? 7   VAL A O   1 
ATOM   2186 C CB  . VAL B 2 11  ? -7.353  -20.038 35.599  1   48.74  ? 7   VAL A CB  1 
ATOM   2187 C CG1 . VAL B 2 11  ? -6.893  -21.442 35.962  1   49.65  ? 7   VAL A CG1 1 
ATOM   2188 C CG2 . VAL B 2 11  ? -8.767  -19.784 36.095  1   45.98  ? 7   VAL A CG2 1 
ATOM   2189 N N   . GLU B 2 12  ? -4.602  -19.241 34.394  1   52.4   ? 8   GLU A N   1 
ATOM   2190 C CA  . GLU B 2 12  ? -3.258  -19.526 33.919  1   53.15  ? 8   GLU A CA  1 
ATOM   2191 C C   . GLU B 2 12  ? -3.139  -19.17  32.44   1   54.1   ? 8   GLU A C   1 
ATOM   2192 O O   . GLU B 2 12  ? -4.131  -19.22  31.71   1   55.66  ? 8   GLU A O   1 
ATOM   2193 C CB  . GLU B 2 12  ? -2.97   -21.015 34.099  1   53.1   ? 8   GLU A CB  1 
ATOM   2194 C CG  . GLU B 2 12  ? -3.939  -21.925 33.354  1   51.68  ? 8   GLU A CG  1 
ATOM   2195 C CD  . GLU B 2 12  ? -3.697  -23.398 33.58   1   52.89  ? 8   GLU A CD  1 
ATOM   2196 O OE1 . GLU B 2 12  ? -3.652  -23.748 34.787  1   54.63  ? 8   GLU A OE1 1 
ATOM   2197 O OE2 . GLU B 2 12  ? -3.582  -24.164 32.58   1   50.29  ? 8   GLU A OE2 1 
ATOM   2198 N N   . LYS B 2 13  ? -1.921  -18.827 31.996  1   55.54  ? 9   LYS A N   1 
ATOM   2199 C CA  . LYS B 2 13  ? -1.623  -18.801 30.572  1   54.32  ? 9   LYS A CA  1 
ATOM   2200 C C   . LYS B 2 13  ? -1.907  -20.201 30.027  1   53.23  ? 9   LYS A C   1 
ATOM   2201 O O   . LYS B 2 13  ? -1.586  -21.171 30.708  1   53.8   ? 9   LYS A O   1 
ATOM   2202 C CB  . LYS B 2 13  ? -0.16   -18.398 30.342  1   57.85  ? 9   LYS A CB  1 
ATOM   2203 C CG  . LYS B 2 13  ? 0.231   -18.336 28.863  1   64.1   ? 9   LYS A CG  1 
ATOM   2204 C CD  . LYS B 2 13  ? 1.719   -18.453 28.523  1   70.8   ? 9   LYS A CD  1 
ATOM   2205 C CE  . LYS B 2 13  ? 1.955   -19.042 27.137  1   67.83  ? 9   LYS A CE  1 
ATOM   2206 N NZ  . LYS B 2 13  ? 3.352   -19.127 26.695  1   63.96  ? 9   LYS A NZ  1 
ATOM   2207 N N   . ILE B 2 14  ? -2.531  -20.264 28.847  1   53.78  ? 10  ILE A N   1 
ATOM   2208 C CA  . ILE B 2 14  ? -2.867  -21.563 28.197  1   55.09  ? 10  ILE A CA  1 
ATOM   2209 C C   . ILE B 2 14  ? -2.262  -21.591 26.788  1   55.33  ? 10  ILE A C   1 
ATOM   2210 O O   . ILE B 2 14  ? -2.377  -22.633 26.122  1   55.19  ? 10  ILE A O   1 
ATOM   2211 C CB  . ILE B 2 14  ? -4.388  -21.782 28.141  1   55.87  ? 10  ILE A CB  1 
ATOM   2212 C CG1 . ILE B 2 14  ? -5.13   -20.628 27.491  1   54.58  ? 10  ILE A CG1 1 
ATOM   2213 C CG2 . ILE B 2 14  ? -4.932  -22.102 29.531  1   59.61  ? 10  ILE A CG2 1 
ATOM   2214 C CD1 . ILE B 2 14  ? -6.611  -20.898 27.311  1   53.56  ? 10  ILE A CD1 1 
ATOM   2215 N N   . GLY B 2 15  ? -1.64   -20.497 26.361  1   58.13  ? 11  GLY A N   1 
ATOM   2216 C CA  . GLY B 2 15  ? -0.988  -20.508 25.047  1   58.5   ? 11  GLY A CA  1 
ATOM   2217 C C   . GLY B 2 15  ? -0.67   -19.134 24.525  1   59.27  ? 11  GLY A C   1 
ATOM   2218 O O   . GLY B 2 15  ? -1.127  -18.156 25.125  1   59.94  ? 11  GLY A O   1 
ATOM   2219 N N   . GLU B 2 16  ? 0.119   -19.072 23.456  1   62.81  ? 12  GLU A N   1 
ATOM   2220 C CA  . GLU B 2 16  ? 0.46    -17.779 22.816  1   70.52  ? 12  GLU A CA  1 
ATOM   2221 C C   . GLU B 2 16  ? -0.101  -17.8   21.393  1   69.33  ? 12  GLU A C   1 
ATOM   2222 O O   . GLU B 2 16  ? 0.075   -18.812 20.704  1   70.52  ? 12  GLU A O   1 
ATOM   2223 C CB  . GLU B 2 16  ? 1.968   -17.551 22.842  1   73.61  ? 12  GLU A CB  1 
ATOM   2224 C CG  . GLU B 2 16  ? 2.518   -17.347 24.249  1   80.64  ? 12  GLU A CG  1 
ATOM   2225 C CD  . GLU B 2 16  ? 4.026   -17.193 24.28   1   88.07  ? 12  GLU A CD  1 
ATOM   2226 O OE1 . GLU B 2 16  ? 4.661   -17.433 23.233  1   85.27  ? 12  GLU A OE1 1 
ATOM   2227 O OE2 . GLU B 2 16  ? 4.562   -16.831 25.347  1   91.77  ? 12  GLU A OE2 1 
ATOM   2228 N N   . GLY B 2 17  ? -0.755  -16.723 20.975  1   74.77  ? 13  GLY A N   1 
ATOM   2229 C CA  . GLY B 2 17  ? -1.427  -16.742 19.67   1   72.52  ? 13  GLY A CA  1 
ATOM   2230 C C   . GLY B 2 17  ? -1.169  -15.497 18.861  1   81.11  ? 13  GLY A C   1 
ATOM   2231 O O   . GLY B 2 17  ? -0.073  -14.921 18.993  1   85.62  ? 13  GLY A O   1 
ATOM   2232 N N   . THR B 2 18  ? -2.15   -15.082 18.063  1   76.74  ? 14  THR A N   1 
ATOM   2233 C CA  . THR B 2 18  ? -1.911  -13.972 17.149  1   72.56  ? 14  THR A CA  1 
ATOM   2234 C C   . THR B 2 18  ? -1.764  -12.649 17.907  1   73.36  ? 14  THR A C   1 
ATOM   2235 O O   . THR B 2 18  ? -0.878  -11.852 17.605  1   74.74  ? 14  THR A O   1 
ATOM   2236 C CB  . THR B 2 18  ? -3.028  -13.908 16.103  1   70.95  ? 14  THR A CB  1 
ATOM   2237 O OG1 . THR B 2 18  ? -3.093  -15.177 15.452  1   65.81  ? 14  THR A OG1 1 
ATOM   2238 C CG2 . THR B 2 18  ? -2.826  -12.777 15.11   1   68.38  ? 14  THR A CG2 1 
ATOM   2239 N N   . TYR B 2 19  ? -2.637  -12.414 18.894  1   70.38  ? 15  TYR A N   1 
ATOM   2240 C CA  . TYR B 2 19  ? -2.714  -11.104 19.522  1   73.49  ? 15  TYR A CA  1 
ATOM   2241 C C   . TYR B 2 19  ? -1.809  -11.051 20.743  1   75.21  ? 15  TYR A C   1 
ATOM   2242 O O   . TYR B 2 19  ? -1.445  -9.967  21.201  1   78.57  ? 15  TYR A O   1 
ATOM   2243 C CB  . TYR B 2 19  ? -4.172  -10.755 19.827  1   76.2   ? 15  TYR A CB  1 
ATOM   2244 C CG  . TYR B 2 19  ? -5.072  -11.121 18.657  1   78.34  ? 15  TYR A CG  1 
ATOM   2245 C CD1 . TYR B 2 19  ? -5.034  -10.398 17.469  1   72.34  ? 15  TYR A CD1 1 
ATOM   2246 C CD2 . TYR B 2 19  ? -5.905  -12.234 18.72   1   80.99  ? 15  TYR A CD2 1 
ATOM   2247 C CE1 . TYR B 2 19  ? -5.83   -10.749 16.393  1   68.02  ? 15  TYR A CE1 1 
ATOM   2248 C CE2 . TYR B 2 19  ? -6.698  -12.597 17.642  1   79.88  ? 15  TYR A CE2 1 
ATOM   2249 C CZ  . TYR B 2 19  ? -6.662  -11.854 16.475  1   71.24  ? 15  TYR A CZ  1 
ATOM   2250 O OH  . TYR B 2 19  ? -7.465  -12.232 15.438  1   69.12  ? 15  TYR A OH  1 
ATOM   2251 N N   . GLY B 2 20  ? -1.46   -12.231 21.256  1   70.68  ? 16  GLY A N   1 
ATOM   2252 C CA  . GLY B 2 20  ? -0.485  -12.302 22.325  1   73.04  ? 16  GLY A CA  1 
ATOM   2253 C C   . GLY B 2 20  ? -0.573  -13.654 23.008  1   72.44  ? 16  GLY A C   1 
ATOM   2254 O O   . GLY B 2 20  ? -0.531  -14.688 22.349  1   75.61  ? 16  GLY A O   1 
ATOM   2255 N N   . VAL B 2 21  ? -0.814  -13.603 24.313  1   70.16  ? 17  VAL A N   1 
ATOM   2256 C CA  . VAL B 2 21  ? -0.982  -14.844 25.106  1   66.4   ? 17  VAL A CA  1 
ATOM   2257 C C   . VAL B 2 21  ? -2.479  -15.08  25.321  1   61.07  ? 17  VAL A C   1 
ATOM   2258 O O   . VAL B 2 21  ? -3.209  -14.088 25.521  1   59.07  ? 17  VAL A O   1 
ATOM   2259 C CB  . VAL B 2 21  ? -0.233  -14.616 26.428  1   69.18  ? 17  VAL A CB  1 
ATOM   2260 C CG1 . VAL B 2 21  ? -0.837  -13.476 27.235  1   74.34  ? 17  VAL A CG1 1 
ATOM   2261 C CG2 . VAL B 2 21  ? -0.142  -15.874 27.278  1   70.36  ? 17  VAL A CG2 1 
ATOM   2262 N N   . VAL B 2 22  ? -2.922  -16.329 25.211  1   51.45  ? 18  VAL A N   1 
ATOM   2263 C CA  . VAL B 2 22  ? -4.339  -16.655 25.534  1   43.53  ? 18  VAL A CA  1 
ATOM   2264 C C   . VAL B 2 22  ? -4.333  -17.074 27.007  1   43.42  ? 18  VAL A C   1 
ATOM   2265 O O   . VAL B 2 22  ? -3.308  -17.581 27.476  1   42.65  ? 18  VAL A O   1 
ATOM   2266 C CB  . VAL B 2 22  ? -4.965  -17.723 24.621  1   39.48  ? 18  VAL A CB  1 
ATOM   2267 C CG1 . VAL B 2 22  ? -6.466  -17.86  24.83   1   39     ? 18  VAL A CG1 1 
ATOM   2268 C CG2 . VAL B 2 22  ? -4.662  -17.433 23.158  1   41.27  ? 18  VAL A CG2 1 
ATOM   2269 N N   . TYR B 2 23  ? -5.433  -16.842 27.7    1   44.81  ? 19  TYR A N   1 
ATOM   2270 C CA  . TYR B 2 23  ? -5.457  -17.119 29.15   1   48.72  ? 19  TYR A CA  1 
ATOM   2271 C C   . TYR B 2 23  ? -6.716  -17.843 29.522  1   45.47  ? 19  TYR A C   1 
ATOM   2272 O O   . TYR B 2 23  ? -7.781  -17.526 28.992  1   42.18  ? 19  TYR A O   1 
ATOM   2273 C CB  . TYR B 2 23  ? -5.364  -15.768 29.863  1   53.46  ? 19  TYR A CB  1 
ATOM   2274 C CG  . TYR B 2 23  ? -4.155  -15.586 30.765  1   63.11  ? 19  TYR A CG  1 
ATOM   2275 C CD1 . TYR B 2 23  ? -4.202  -15.955 32.1    1   73.45  ? 19  TYR A CD1 1 
ATOM   2276 C CD2 . TYR B 2 23  ? -2.975  -15.041 30.282  1   67.81  ? 19  TYR A CD2 1 
ATOM   2277 C CE1 . TYR B 2 23  ? -3.105  -15.797 32.929  1   76.71  ? 19  TYR A CE1 1 
ATOM   2278 C CE2 . TYR B 2 23  ? -1.874  -14.868 31.102  1   75.3   ? 19  TYR A CE2 1 
ATOM   2279 C CZ  . TYR B 2 23  ? -1.939  -15.249 32.429  1   78.03  ? 19  TYR A CZ  1 
ATOM   2280 O OH  . TYR B 2 23  ? -0.863  -15.088 33.251  1   78.08  ? 19  TYR A OH  1 
ATOM   2281 N N   . LYS B 2 24  ? -6.584  -18.839 30.385  1   44.79  ? 20  LYS A N   1 
ATOM   2282 C CA  . LYS B 2 24  ? -7.744  -19.516 30.934  1   42.99  ? 20  LYS A CA  1 
ATOM   2283 C C   . LYS B 2 24  ? -8.244  -18.662 32.081  1   43.07  ? 20  LYS A C   1 
ATOM   2284 O O   . LYS B 2 24  ? -7.451  -18.217 32.893  1   46.57  ? 20  LYS A O   1 
ATOM   2285 C CB  . LYS B 2 24  ? -7.434  -20.936 31.423  1   44.31  ? 20  LYS A CB  1 
ATOM   2286 C CG  . LYS B 2 24  ? -8.557  -21.692 32.14   1   43.32  ? 20  LYS A CG  1 
ATOM   2287 C CD  . LYS B 2 24  ? -8.299  -23.193 32.218  1   45.05  ? 20  LYS A CD  1 
ATOM   2288 C CE  . LYS B 2 24  ? -9.167  -23.895 33.218  1   49.24  ? 20  LYS A CE  1 
ATOM   2289 N NZ  . LYS B 2 24  ? -9.132  -25.365 33.199  1   48.75  ? 20  LYS A NZ  1 
ATOM   2290 N N   . ALA B 2 25  ? -9.552  -18.418 32.113  1   40.27  ? 21  ALA A N   1 
ATOM   2291 C CA  . ALA B 2 25  ? -10.158 -17.631 33.17   1   40.17  ? 21  ALA A CA  1 
ATOM   2292 C C   . ALA B 2 25  ? -11.55  -18.186 33.44   1   38.53  ? 21  ALA A C   1 
ATOM   2293 O O   . ALA B 2 25  ? -12.069 -18.98  32.654  1   36.1   ? 21  ALA A O   1 
ATOM   2294 C CB  . ALA B 2 25  ? -10.209 -16.183 32.757  1   40.31  ? 21  ALA A CB  1 
ATOM   2295 N N   . ARG B 2 26  ? -12.135 -17.763 34.562  1   39.68  ? 22  ARG A N   1 
ATOM   2296 C CA  . ARG B 2 26  ? -13.42  -18.283 34.983  1   39.8   ? 22  ARG A CA  1 
ATOM   2297 C C   . ARG B 2 26  ? -14.353 -17.115 35.248  1   39.67  ? 22  ARG A C   1 
ATOM   2298 O O   . ARG B 2 26  ? -13.984 -16.182 35.94   1   42.19  ? 22  ARG A O   1 
ATOM   2299 C CB  . ARG B 2 26  ? -13.261 -19.052 36.296  1   43.49  ? 22  ARG A CB  1 
ATOM   2300 C CG  . ARG B 2 26  ? -14.557 -19.523 36.943  1   47.63  ? 22  ARG A CG  1 
ATOM   2301 C CD  . ARG B 2 26  ? -14.308 -20.245 38.268  1   54.3   ? 22  ARG A CD  1 
ATOM   2302 N NE  . ARG B 2 26  ? -13.197 -21.215 38.197  1   61.3   ? 22  ARG A NE  1 
ATOM   2303 C CZ  . ARG B 2 26  ? -13.179 -22.428 37.586  1   60.47  ? 22  ARG A CZ  1 
ATOM   2304 N NH1 . ARG B 2 26  ? -14.286 -22.932 37.021  1   55.72  ? 22  ARG A NH1 1 
ATOM   2305 N NH2 . ARG B 2 26  ? -12.046 -23.132 37.575  1   57.35  ? 22  ARG A NH2 1 
ATOM   2306 N N   . ASN B 2 27  ? -15.562 -17.18  34.689  1   37.2   ? 23  ASN A N   1 
ATOM   2307 C CA  . ASN B 2 27  ? -16.61  -16.242 35.051  1   37.58  ? 23  ASN A CA  1 
ATOM   2308 C C   . ASN B 2 27  ? -16.945 -16.443 36.526  1   39.42  ? 23  ASN A C   1 
ATOM   2309 O O   . ASN B 2 27  ? -17.196 -17.553 36.984  1   39.64  ? 23  ASN A O   1 
ATOM   2310 C CB  . ASN B 2 27  ? -17.866 -16.44  34.212  1   35.16  ? 23  ASN A CB  1 
ATOM   2311 C CG  . ASN B 2 27  ? -18.884 -15.346 34.412  1   35.57  ? 23  ASN A CG  1 
ATOM   2312 O OD1 . ASN B 2 27  ? -19.202 -14.983 35.557  1   37.05  ? 23  ASN A OD1 1 
ATOM   2313 N ND2 . ASN B 2 27  ? -19.395 -14.82  33.304  1   33.43  ? 23  ASN A ND2 1 
ATOM   2314 N N   . LYS B 2 28  ? -16.992 -15.353 37.274  1   41.47  ? 24  LYS A N   1 
ATOM   2315 C CA  . LYS B 2 28  ? -17.143 -15.505 38.706  1   43.58  ? 24  LYS A CA  1 
ATOM   2316 C C   . LYS B 2 28  ? -18.616 -15.552 39.094  1   43.33  ? 24  LYS A C   1 
ATOM   2317 O O   . LYS B 2 28  ? -18.909 -15.776 40.255  1   45.11  ? 24  LYS A O   1 
ATOM   2318 C CB  . LYS B 2 28  ? -16.475 -14.324 39.407  1   47.06  ? 24  LYS A CB  1 
ATOM   2319 C CG  . LYS B 2 28  ? -15.003 -14.486 39.657  1   50.39  ? 24  LYS A CG  1 
ATOM   2320 C CD  . LYS B 2 28  ? -14.392 -13.324 40.442  1   55.64  ? 24  LYS A CD  1 
ATOM   2321 C CE  . LYS B 2 28  ? -13.948 -12.194 39.548  1   56.5   ? 24  LYS A CE  1 
ATOM   2322 N NZ  . LYS B 2 28  ? -13.541 -11.016 40.32   1   59.7   ? 24  LYS A NZ  1 
ATOM   2323 N N   . LEU B 2 29  ? -19.537 -15.358 38.141  1   41.66  ? 25  LEU A N   1 
ATOM   2324 C CA  . LEU B 2 29  ? -20.948 -15.226 38.483  1   41.73  ? 25  LEU A CA  1 
ATOM   2325 C C   . LEU B 2 29  ? -21.754 -16.426 37.988  1   40.96  ? 25  LEU A C   1 
ATOM   2326 O O   . LEU B 2 29  ? -22.71  -16.847 38.638  1   42.24  ? 25  LEU A O   1 
ATOM   2327 C CB  . LEU B 2 29  ? -21.467 -13.925 37.879  1   40.25  ? 25  LEU A CB  1 
ATOM   2328 C CG  . LEU B 2 29  ? -21.019 -12.647 38.58   1   41.03  ? 25  LEU A CG  1 
ATOM   2329 C CD1 . LEU B 2 29  ? -21.69  -11.489 37.874  1   40.67  ? 25  LEU A CD1 1 
ATOM   2330 C CD2 . LEU B 2 29  ? -21.387 -12.674 40.038  1   42.41  ? 25  LEU A CD2 1 
ATOM   2331 N N   . THR B 2 30  ? -21.368 -16.941 36.821  1   39.26  ? 26  THR A N   1 
ATOM   2332 C CA  . THR B 2 30  ? -22.039 -18.064 36.195  1   39.66  ? 26  THR A CA  1 
ATOM   2333 C C   . THR B 2 30  ? -21.182 -19.335 36.288  1   40.83  ? 26  THR A C   1 
ATOM   2334 O O   . THR B 2 30  ? -21.697 -20.452 36.141  1   40.77  ? 26  THR A O   1 
ATOM   2335 C CB  . THR B 2 30  ? -22.28  -17.716 34.731  1   39.32  ? 26  THR A CB  1 
ATOM   2336 O OG1 . THR B 2 30  ? -20.986 -17.77  34.12   1   39.11  ? 26  THR A OG1 1 
ATOM   2337 C CG2 . THR B 2 30  ? -22.999 -16.393 34.564  1   39.78  ? 26  THR A CG2 1 
ATOM   2338 N N   . GLY B 2 31  ? -19.861 -19.176 36.458  1   40.44  ? 27  GLY A N   1 
ATOM   2339 C CA  . GLY B 2 31  ? -18.973 -20.306 36.699  1   38.44  ? 27  GLY A CA  1 
ATOM   2340 C C   . GLY B 2 31  ? -18.314 -20.839 35.426  1   35.78  ? 27  GLY A C   1 
ATOM   2341 O O   . GLY B 2 31  ? -17.439 -21.703 35.513  1   35.27  ? 27  GLY A O   1 
ATOM   2342 N N   . GLU B 2 32  ? -18.706 -20.278 34.273  1   33.8   ? 28  GLU A N   1 
ATOM   2343 C CA  . GLU B 2 32  ? -18.228 -20.706 32.969  1   32.65  ? 28  GLU A CA  1 
ATOM   2344 C C   . GLU B 2 32  ? -16.735 -20.429 32.79   1   32.91  ? 28  GLU A C   1 
ATOM   2345 O O   . GLU B 2 32  ? -16.238 -19.348 33.057  1   33.6   ? 28  GLU A O   1 
ATOM   2346 C CB  . GLU B 2 32  ? -19.05  -20.014 31.882  1   31.64  ? 28  GLU A CB  1 
ATOM   2347 C CG  . GLU B 2 32  ? -18.55  -20.302 30.473  1   30.64  ? 28  GLU A CG  1 
ATOM   2348 C CD  . GLU B 2 32  ? -19.411 -19.58  29.453  1   31.54  ? 28  GLU A CD  1 
ATOM   2349 O OE1 . GLU B 2 32  ? -19.901 -18.491 29.822  1   32.52  ? 28  GLU A OE1 1 
ATOM   2350 O OE2 . GLU B 2 32  ? -19.562 -20.065 28.302  1   30.1   ? 28  GLU A OE2 1 
ATOM   2351 N N   . VAL B 2 33  ? -16.029 -21.437 32.298  1   32.73  ? 29  VAL A N   1 
ATOM   2352 C CA  . VAL B 2 33  ? -14.613 -21.338 32.015  1   33.49  ? 29  VAL A CA  1 
ATOM   2353 C C   . VAL B 2 33  ? -14.472 -20.86  30.58   1   32.9   ? 29  VAL A C   1 
ATOM   2354 O O   . VAL B 2 33  ? -15.058 -21.456 29.679  1   33.9   ? 29  VAL A O   1 
ATOM   2355 C CB  . VAL B 2 33  ? -13.935 -22.711 32.2    1   32.93  ? 29  VAL A CB  1 
ATOM   2356 C CG1 . VAL B 2 33  ? -12.441 -22.654 31.928  1   33.48  ? 29  VAL A CG1 1 
ATOM   2357 C CG2 . VAL B 2 33  ? -14.156 -23.25  33.601  1   34.63  ? 29  VAL A CG2 1 
ATOM   2358 N N   . VAL B 2 34  ? -13.652 -19.825 30.392  1   32.62  ? 30  VAL A N   1 
ATOM   2359 C CA  . VAL B 2 34  ? -13.482 -19.168 29.107  1   30.8   ? 30  VAL A CA  1 
ATOM   2360 C C   . VAL B 2 34  ? -11.995 -19.059 28.796  1   31.74  ? 30  VAL A C   1 
ATOM   2361 O O   . VAL B 2 34  ? -11.154 -19.336 29.65   1   33.89  ? 30  VAL A O   1 
ATOM   2362 C CB  . VAL B 2 34  ? -14.125 -17.777 29.155  1   31.36  ? 30  VAL A CB  1 
ATOM   2363 C CG1 . VAL B 2 34  ? -15.615 -17.896 29.401  1   31.36  ? 30  VAL A CG1 1 
ATOM   2364 C CG2 . VAL B 2 34  ? -13.478 -16.873 30.204  1   32.84  ? 30  VAL A CG2 1 
ATOM   2365 N N   . ALA B 2 35  ? -11.688 -18.707 27.549  1   30.3   ? 31  ALA A N   1 
ATOM   2366 C CA  . ALA B 2 35  ? -10.344 -18.328 27.17   1   31.7   ? 31  ALA A CA  1 
ATOM   2367 C C   . ALA B 2 35  ? -10.373 -16.849 26.787  1   34.58  ? 31  ALA A C   1 
ATOM   2368 O O   . ALA B 2 35  ? -11.232 -16.411 26.027  1   33.62  ? 31  ALA A O   1 
ATOM   2369 C CB  . ALA B 2 35  ? -9.855  -19.2   26.04   1   29.08  ? 31  ALA A CB  1 
ATOM   2370 N N   . LEU B 2 36  ? -9.431  -16.075 27.324  1   37.63  ? 32  LEU A N   1 
ATOM   2371 C CA  . LEU B 2 36  ? -9.391  -14.66  27.023  1   38.46  ? 32  LEU A CA  1 
ATOM   2372 C C   . LEU B 2 36  ? -8.212  -14.415 26.098  1   41.57  ? 32  LEU A C   1 
ATOM   2373 O O   . LEU B 2 36  ? -7.079  -14.753 26.429  1   43.89  ? 32  LEU A O   1 
ATOM   2374 C CB  . LEU B 2 36  ? -9.284  -13.871 28.319  1   38.44  ? 32  LEU A CB  1 
ATOM   2375 C CG  . LEU B 2 36  ? -10.431 -14.092 29.31   1   38.27  ? 32  LEU A CG  1 
ATOM   2376 C CD1 . LEU B 2 36  ? -10.219 -13.324 30.594  1   39.77  ? 32  LEU A CD1 1 
ATOM   2377 C CD2 . LEU B 2 36  ? -11.8   -13.777 28.736  1   37.02  ? 32  LEU A CD2 1 
ATOM   2378 N N   . LYS B 2 37  ? -8.518  -13.884 24.909  1   42.55  ? 33  LYS A N   1 
ATOM   2379 C CA  . LYS B 2 37  ? -7.505  -13.385 23.993  1   44.39  ? 33  LYS A CA  1 
ATOM   2380 C C   . LYS B 2 37  ? -7.377  -11.872 24.204  1   46.27  ? 33  LYS A C   1 
ATOM   2381 O O   . LYS B 2 37  ? -8.381  -11.175 24.255  1   49.45  ? 33  LYS A O   1 
ATOM   2382 C CB  . LYS B 2 37  ? -7.983  -13.884 22.63   1   44.78  ? 33  LYS A CB  1 
ATOM   2383 C CG  . LYS B 2 37  ? -6.905  -14.217 21.628  1   53.69  ? 33  LYS A CG  1 
ATOM   2384 C CD  . LYS B 2 37  ? -7.381  -14.83  20.306  1   60.97  ? 33  LYS A CD  1 
ATOM   2385 C CE  . LYS B 2 37  ? -6.994  -16.254 20.011  1   64.78  ? 33  LYS A CE  1 
ATOM   2386 N NZ  . LYS B 2 37  ? -6.953  -16.509 18.562  1   61.83  ? 33  LYS A NZ  1 
ATOM   2387 N N   . LYS B 2 38  ? -6.161  -11.348 24.375  1   47.12  ? 34  LYS A N   1 
ATOM   2388 C CA  . LYS B 2 38  ? -6.005  -9.946  24.754  1   51.61  ? 34  LYS A CA  1 
ATOM   2389 C C   . LYS B 2 38  ? -5.219  -9.189  23.683  1   57.11  ? 34  LYS A C   1 
ATOM   2390 O O   . LYS B 2 38  ? -4.171  -9.662  23.25   1   63.38  ? 34  LYS A O   1 
ATOM   2391 C CB  . LYS B 2 38  ? -5.292  -9.782  26.1    1   51.67  ? 34  LYS A CB  1 
ATOM   2392 C CG  . LYS B 2 38  ? -4.869  -8.368  26.474  1   53.1   ? 34  LYS A CG  1 
ATOM   2393 C CD  . LYS B 2 38  ? -3.985  -8.265  27.714  1   56.07  ? 34  LYS A CD  1 
ATOM   2394 C CE  . LYS B 2 38  ? -3.78   -6.841  28.178  1   60.26  ? 34  LYS A CE  1 
ATOM   2395 N NZ  . LYS B 2 38  ? -2.878  -6.725  29.329  1   64.2   ? 34  LYS A NZ  1 
ATOM   2396 N N   . ILE B 2 39  ? -5.718  -8.004  23.296  1   57.78  ? 35  ILE A N   1 
ATOM   2397 C CA  . ILE B 2 39  ? -5.163  -7.211  22.213  1   59.45  ? 35  ILE A CA  1 
ATOM   2398 C C   . ILE B 2 39  ? -4.986  -5.79   22.723  1   68.58  ? 35  ILE A C   1 
ATOM   2399 O O   . ILE B 2 39  ? -5.983  -5.12   22.988  1   72.37  ? 35  ILE A O   1 
ATOM   2400 C CB  . ILE B 2 39  ? -6.113  -7.204  21.003  1   56.87  ? 35  ILE A CB  1 
ATOM   2401 C CG1 . ILE B 2 39  ? -6.715  -8.589  20.719  1   57.24  ? 35  ILE A CG1 1 
ATOM   2402 C CG2 . ILE B 2 39  ? -5.381  -6.634  19.794  1   56.06  ? 35  ILE A CG2 1 
ATOM   2403 C CD1 . ILE B 2 39  ? -7.383  -8.758  19.364  1   55.63  ? 35  ILE A CD1 1 
ATOM   2404 N N   . ARG B 2 40  ? -3.888  -5.32   23.034  1   78.57  ? 36  ARG A N   1 
ATOM   2405 C CA  . ARG B 2 40  ? -3.684  -3.93   23.514  1   86.06  ? 36  ARG A CA  1 
ATOM   2406 C C   . ARG B 2 40  ? -3.633  -3.03   22.284  1   87.34  ? 36  ARG A C   1 
ATOM   2407 O O   . ARG B 2 40  ? -2.912  -3.367  21.33   1   87.02  ? 36  ARG A O   1 
ATOM   2408 C CB  . ARG B 2 40  ? -2.382  -3.784  24.305  1   89.06  ? 36  ARG A CB  1 
ATOM   2409 C CG  . ARG B 2 40  ? -2.036  -2.335  24.62   1   102.66 ? 36  ARG A CG  1 
ATOM   2410 C CD  . ARG B 2 40  ? -0.945  -2.213  25.669  1   107.17 ? 36  ARG A CD  1 
ATOM   2411 N NE  . ARG B 2 40  ? -1.427  -2.515  27.021  1   105.54 ? 36  ARG A NE  1 
ATOM   2412 C CZ  . ARG B 2 40  ? -0.916  -3.453  27.81   1   104.67 ? 36  ARG A CZ  1 
ATOM   2413 N NH1 . ARG B 2 40  ? -0.556  -3.153  29.044  1   102.68 ? 36  ARG A NH1 1 
ATOM   2414 N NH2 . ARG B 2 40  ? -0.77   -4.687  27.363  1   103.69 ? 36  ARG A NH2 1 
ATOM   2415 N N   . LEU B 2 41  ? -4.241  -1.977  22.262  1   89.11  ? 37  LEU A N   1 
ATOM   2416 C CA  . LEU B 2 41  ? -4.442  -1.124  21.07   1   94.33  ? 37  LEU A CA  1 
ATOM   2417 C C   . LEU B 2 41  ? -3.557  0.127   21.096  1   108.23 ? 37  LEU A C   1 
ATOM   2418 O O   . LEU B 2 41  ? -3.134  0.528   20.01   1   114.57 ? 37  LEU A O   1 
ATOM   2419 C CB  . LEU B 2 41  ? -5.933  -0.793  21.031  1   84.88  ? 37  LEU A CB  1 
ATOM   2420 C CG  . LEU B 2 41  ? -6.882  -1.993  21.075  1   71.34  ? 37  LEU A CG  1 
ATOM   2421 C CD1 . LEU B 2 41  ? -8.278  -1.538  21.443  1   69.67  ? 37  LEU A CD1 1 
ATOM   2422 C CD2 . LEU B 2 41  ? -6.883  -2.697  19.734  1   63.88  ? 37  LEU A CD2 1 
ATOM   2423 N N   . ASP B 2 42  ? -3.29   0.729   22.257  1   110.56 ? 38  ASP A N   1 
ATOM   2424 C CA  . ASP B 2 42  ? -2.373  1.902   22.236  1   113.89 ? 38  ASP A CA  1 
ATOM   2425 C C   . ASP B 2 42  ? -1.103  1.467   21.508  1   117.64 ? 38  ASP A C   1 
ATOM   2426 O O   . ASP B 2 42  ? -0.683  2.183   20.581  1   122.33 ? 38  ASP A O   1 
ATOM   2427 C CB  . ASP B 2 42  ? -2.145  2.495   23.619  1   112.47 ? 38  ASP A CB  1 
ATOM   2428 C CG  . ASP B 2 42  ? -1.613  1.561   24.693  1   110.07 ? 38  ASP A CG  1 
ATOM   2429 O OD1 . ASP B 2 42  ? -0.571  0.918   24.456  1   103.03 ? 38  ASP A OD1 1 
ATOM   2430 O OD2 . ASP B 2 42  ? -2.234  1.508   25.772  1   112.92 ? 38  ASP A OD2 1 
ATOM   2431 N N   . THR B 2 43  ? -0.544  0.322   21.895  1   113.86 ? 39  THR A N   1 
ATOM   2432 C CA  . THR B 2 43  ? 0.652   -0.221  21.227  1   112.8  ? 39  THR A CA  1 
ATOM   2433 C C   . THR B 2 43  ? 0.431   -0.204  19.734  1   115.3  ? 39  THR A C   1 
ATOM   2434 O O   . THR B 2 43  ? 1.386   0.124   19.005  1   125.7  ? 39  THR A O   1 
ATOM   2435 C CB  . THR B 2 43  ? 0.867   -1.636  21.76   1   30     ? 39  THR A CB  1 
ATOM   2436 O OG1 . THR B 2 43  ? 1.735   -1.473  22.877  1   30     ? 39  THR A OG1 1 
ATOM   2437 C CG2 . THR B 2 43  ? 1.482   -2.581  20.743  1   30     ? 39  THR A CG2 1 
ATOM   2438 N N   . GLU B 2 44  ? -0.788  -0.512  19.285  1   106.39 ? 40  GLU A N   1 
ATOM   2439 C CA  . GLU B 2 44  ? -1.064  -0.61   17.83   1   98.27  ? 40  GLU A CA  1 
ATOM   2440 C C   . GLU B 2 44  ? -1.225  0.793   17.241  1   99.4   ? 40  GLU A C   1 
ATOM   2441 O O   . GLU B 2 44  ? -2.161  1.511   17.639  1   103.3  ? 40  GLU A O   1 
ATOM   2442 C CB  . GLU B 2 44  ? -2.325  -1.43   17.576  1   30     ? 40  GLU A CB  1 
ATOM   2443 C CG  . GLU B 2 44  ? -2.224  -2.871  18.058  1   30     ? 40  GLU A CG  1 
ATOM   2444 C CD  . GLU B 2 44  ? -1.14   -3.665  17.361  1   30     ? 40  GLU A CD  1 
ATOM   2445 O OE1 . GLU B 2 44  ? -1.222  -3.826  16.128  1   30     ? 40  GLU A OE1 1 
ATOM   2446 O OE2 . GLU B 2 44  ? -0.213  -4.122  18.056  1   30     ? 40  GLU A OE2 1 
ATOM   2447 N N   . THR B 2 45  ? -0.354  1.155   16.305  1   97.1   ? 41  THR A N   1 
ATOM   2448 C CA  . THR B 2 45  ? -0.411  2.507   15.718  1   99.5   ? 41  THR A CA  1 
ATOM   2449 C C   . THR B 2 45  ? -1.42   2.522   14.599  1   91.3   ? 41  THR A C   1 
ATOM   2450 O O   . THR B 2 45  ? -1.752  3.622   14.122  1   94.54  ? 41  THR A O   1 
ATOM   2451 C CB  . THR B 2 45  ? 0.98    2.881   15.223  1   102.18 ? 41  THR A CB  1 
ATOM   2452 O OG1 . THR B 2 45  ? 1.341   1.891   14.266  1   99.37  ? 41  THR A OG1 1 
ATOM   2453 C CG2 . THR B 2 45  ? 2       2.899   16.347  1   99.63  ? 41  THR A CG2 1 
ATOM   2454 N N   . GLU B 2 46  ? -1.874  1.347   14.174  1   76.73  ? 42  GLU A N   1 
ATOM   2455 C CA  . GLU B 2 46  ? -2.815  1.262   13.033  1   70.26  ? 42  GLU A CA  1 
ATOM   2456 C C   . GLU B 2 46  ? -4.212  1.006   13.59   1   63.21  ? 42  GLU A C   1 
ATOM   2457 O O   . GLU B 2 46  ? -5.129  0.741   12.802  1   60.96  ? 42  GLU A O   1 
ATOM   2458 C CB  . GLU B 2 46  ? -2.376  0.175   12.055  1   69.92  ? 42  GLU A CB  1 
ATOM   2459 C CG  . GLU B 2 46  ? -1.097  0.534   11.306  1   74.03  ? 42  GLU A CG  1 
ATOM   2460 C CD  . GLU B 2 46  ? -1.315  1.522   10.177  1   78.53  ? 42  GLU A CD  1 
ATOM   2461 O OE1 . GLU B 2 46  ? -2.191  1.253   9.335   1   78.44  ? 42  GLU A OE1 1 
ATOM   2462 O OE2 . GLU B 2 46  ? -0.621  2.556   10.142  1   80.18  ? 42  GLU A OE2 1 
ATOM   2463 N N   . GLY B 2 47  ? -4.342  1.096   14.906  1   59.94  ? 43  GLY A N   1 
ATOM   2464 C CA  . GLY B 2 47  ? -5.644  0.876   15.541  1   55.13  ? 43  GLY A CA  1 
ATOM   2465 C C   . GLY B 2 47  ? -5.97   -0.587  15.616  1   49.61  ? 43  GLY A C   1 
ATOM   2466 O O   . GLY B 2 47  ? -5.047  -1.388  15.795  1   48.46  ? 43  GLY A O   1 
ATOM   2467 N N   . VAL B 2 48  ? -7.245  -0.92   15.463  1   46.64  ? 44  VAL A N   1 
ATOM   2468 C CA  . VAL B 2 48  ? -7.646  -2.309  15.612  1   42.42  ? 44  VAL A CA  1 
ATOM   2469 C C   . VAL B 2 48  ? -7.002  -3.109  14.486  1   40.91  ? 44  VAL A C   1 
ATOM   2470 O O   . VAL B 2 48  ? -7.131  -2.74   13.33   1   40.98  ? 44  VAL A O   1 
ATOM   2471 C CB  . VAL B 2 48  ? -9.17   -2.506  15.621  1   40.01  ? 44  VAL A CB  1 
ATOM   2472 C CG1 . VAL B 2 48  ? -9.526  -3.965  15.843  1   36.58  ? 44  VAL A CG1 1 
ATOM   2473 C CG2 . VAL B 2 48  ? -9.859  -1.613  16.631  1   41.4   ? 44  VAL A CG2 1 
ATOM   2474 N N   . PRO B 2 49  ? -6.245  -4.187  14.777  1   39.73  ? 45  PRO A N   1 
ATOM   2475 C CA  . PRO B 2 49  ? -5.567  -4.953  13.725  1   38.99  ? 45  PRO A CA  1 
ATOM   2476 C C   . PRO B 2 49  ? -6.513  -5.653  12.763  1   37.03  ? 45  PRO A C   1 
ATOM   2477 O O   . PRO B 2 49  ? -7.547  -6.139  13.192  1   36.5   ? 45  PRO A O   1 
ATOM   2478 C CB  . PRO B 2 49  ? -4.722  -5.964  14.507  1   37.78  ? 45  PRO A CB  1 
ATOM   2479 C CG  . PRO B 2 49  ? -4.553  -5.292  15.856  1   39.58  ? 45  PRO A CG  1 
ATOM   2480 C CD  . PRO B 2 49  ? -5.889  -4.64   16.126  1   39.54  ? 45  PRO A CD  1 
ATOM   2481 N N   . SER B 2 50  ? -6.137  -5.72   11.477  1   36.77  ? 46  SER A N   1 
ATOM   2482 C CA  . SER B 2 50  ? -7.011  -6.262  10.456  1   35.32  ? 46  SER A CA  1 
ATOM   2483 C C   . SER B 2 50  ? -7.353  -7.692  10.842  1   34.56  ? 46  SER A C   1 
ATOM   2484 O O   . SER B 2 50  ? -8.421  -8.208  10.519  1   34.21  ? 46  SER A O   1 
ATOM   2485 C CB  . SER B 2 50  ? -6.391  -6.191  9.084   1   35.78  ? 46  SER A CB  1 
ATOM   2486 O OG  . SER B 2 50  ? -5.306  -7.103  8.918   1   35.52  ? 46  SER A OG  1 
ATOM   2487 N N   . THR B 2 51  ? -6.433  -8.324  11.572  1   36.03  ? 47  THR A N   1 
ATOM   2488 C CA  . THR B 2 51  ? -6.537  -9.727  11.942  1   33.61  ? 47  THR A CA  1 
ATOM   2489 C C   . THR B 2 51  ? -7.721  -9.883  12.894  1   31.74  ? 47  THR A C   1 
ATOM   2490 O O   . THR B 2 51  ? -8.526  -10.799 12.751  1   29.79  ? 47  THR A O   1 
ATOM   2491 C CB  . THR B 2 51  ? -5.205  -10.164 12.556  1   35.48  ? 47  THR A CB  1 
ATOM   2492 O OG1 . THR B 2 51  ? -4.124  -9.449  11.948  1   38.91  ? 47  THR A OG1 1 
ATOM   2493 C CG2 . THR B 2 51  ? -4.954  -11.648 12.377  1   34     ? 47  THR A CG2 1 
ATOM   2494 N N   . ALA B 2 52  ? -7.846  -8.937  13.821  1   32.1   ? 48  ALA A N   1 
ATOM   2495 C CA  . ALA B 2 52  ? -8.889  -8.995  14.821  1   32.13  ? 48  ALA A CA  1 
ATOM   2496 C C   . ALA B 2 52  ? -10.222 -8.631  14.192  1   32.34  ? 48  ALA A C   1 
ATOM   2497 O O   . ALA B 2 52  ? -11.216 -9.288  14.465  1   32.43  ? 48  ALA A O   1 
ATOM   2498 C CB  . ALA B 2 52  ? -8.556  -8.069  15.964  1   34.5   ? 48  ALA A CB  1 
ATOM   2499 N N   . ILE B 2 53  ? -10.225 -7.6    13.342  1   33.3   ? 49  ILE A N   1 
ATOM   2500 C CA  . ILE B 2 53  ? -11.406 -7.169  12.606  1   32.78  ? 49  ILE A CA  1 
ATOM   2501 C C   . ILE B 2 53  ? -11.986 -8.327  11.797  1   30.56  ? 49  ILE A C   1 
ATOM   2502 O O   . ILE B 2 53  ? -13.192 -8.517  11.75   1   30.51  ? 49  ILE A O   1 
ATOM   2503 C CB  . ILE B 2 53  ? -11.041 -5.937  11.762  1   34.32  ? 49  ILE A CB  1 
ATOM   2504 C CG1 . ILE B 2 53  ? -11.141 -4.715  12.651  1   36.71  ? 49  ILE A CG1 1 
ATOM   2505 C CG2 . ILE B 2 53  ? -11.865 -5.805  10.479  1   33.08  ? 49  ILE A CG2 1 
ATOM   2506 C CD1 . ILE B 2 53  ? -10.268 -3.578  12.188  1   40.29  ? 49  ILE A CD1 1 
ATOM   2507 N N   . ARG B 2 54  ? -11.115 -9.147  11.223  1   29.31  ? 50  ARG A N   1 
ATOM   2508 C CA  . ARG B 2 54  ? -11.599 -10.342 10.562  1   28.06  ? 50  ARG A CA  1 
ATOM   2509 C C   . ARG B 2 54  ? -12.068 -11.393 11.565  1   27.21  ? 50  ARG A C   1 
ATOM   2510 O O   . ARG B 2 54  ? -13.147 -11.939 11.414  1   26.26  ? 50  ARG A O   1 
ATOM   2511 C CB  . ARG B 2 54  ? -10.552 -10.862 9.572   1   27.46  ? 50  ARG A CB  1 
ATOM   2512 C CG  . ARG B 2 54  ? -10.404 -9.99   8.333   1   28.08  ? 50  ARG A CG  1 
ATOM   2513 C CD  . ARG B 2 54  ? -9.392  -10.566 7.408   1   27.27  ? 50  ARG A CD  1 
ATOM   2514 N NE  . ARG B 2 54  ? -9.111  -9.663  6.292   1   29.7   ? 50  ARG A NE  1 
ATOM   2515 C CZ  . ARG B 2 54  ? -8.233  -9.964  5.328   1   30.1   ? 50  ARG A CZ  1 
ATOM   2516 N NH1 . ARG B 2 54  ? -7.564  -11.104 5.392   1   28.28  ? 50  ARG A NH1 1 
ATOM   2517 N NH2 . ARG B 2 54  ? -8.011  -9.127  4.326   1   31.28  ? 50  ARG A NH2 1 
ATOM   2518 N N   . GLU B 2 55  ? -11.273 -11.679 12.597  1   28.98  ? 51  GLU A N   1 
ATOM   2519 C CA  . GLU B 2 55  ? -11.584 -12.84  13.417  1   29.5   ? 51  GLU A CA  1 
ATOM   2520 C C   . GLU B 2 55  ? -12.937 -12.629 14.087  1   29.48  ? 51  GLU A C   1 
ATOM   2521 O O   . GLU B 2 55  ? -13.758 -13.538 14.113  1   28.1   ? 51  GLU A O   1 
ATOM   2522 C CB  . GLU B 2 55  ? -10.481 -13.175 14.414  1   32.05  ? 51  GLU A CB  1 
ATOM   2523 C CG  . GLU B 2 55  ? -10.922 -14.233 15.413  1   34.74  ? 51  GLU A CG  1 
ATOM   2524 C CD  . GLU B 2 55  ? -9.826  -15.057 16.076  1   41.27  ? 51  GLU A CD  1 
ATOM   2525 O OE1 . GLU B 2 55  ? -8.757  -14.453 16.412  1   44.57  ? 51  GLU A OE1 1 
ATOM   2526 O OE2 . GLU B 2 55  ? -10.066 -16.3   16.29   1   39.07  ? 51  GLU A OE2 1 
ATOM   2527 N N   . ILE B 2 56  ? -13.167 -11.398 14.552  1   29.95  ? 52  ILE A N   1 
ATOM   2528 C CA  . ILE B 2 56  ? -14.347 -11.032 15.314  1   30.04  ? 52  ILE A CA  1 
ATOM   2529 C C   . ILE B 2 56  ? -15.569 -11.062 14.402  1   29.69  ? 52  ILE A C   1 
ATOM   2530 O O   . ILE B 2 56  ? -16.476 -11.842 14.656  1   29.21  ? 52  ILE A O   1 
ATOM   2531 C CB  . ILE B 2 56  ? -14.15  -9.685  16.055  1   32.03  ? 52  ILE A CB  1 
ATOM   2532 C CG1 . ILE B 2 56  ? -12.969 -9.727  17.056  1   31.04  ? 52  ILE A CG1 1 
ATOM   2533 C CG2 . ILE B 2 56  ? -15.438 -9.194  16.727  1   31.05  ? 52  ILE A CG2 1 
ATOM   2534 C CD1 . ILE B 2 56  ? -12.441 -8.366  17.463  1   31.45  ? 52  ILE A CD1 1 
ATOM   2535 N N   . SER B 2 57  ? -15.616 -10.206 13.374  1   32.46  ? 53  SER A N   1 
ATOM   2536 C CA  . SER B 2 57  ? -16.769 -10.152 12.463  1   35.68  ? 53  SER A CA  1 
ATOM   2537 C C   . SER B 2 57  ? -17.131 -11.53  11.88   1   33.91  ? 53  SER A C   1 
ATOM   2538 O O   . SER B 2 57  ? -18.302 -11.891 11.818  1   35.01  ? 53  SER A O   1 
ATOM   2539 C CB  . SER B 2 57  ? -16.616 -9.112  11.356  1   36.1   ? 53  SER A CB  1 
ATOM   2540 O OG  . SER B 2 57  ? -15.42  -9.313  10.609  1   35.13  ? 53  SER A OG  1 
ATOM   2541 N N   . LEU B 2 58  ? -16.127 -12.317 11.494  1   31.13  ? 54  LEU A N   1 
ATOM   2542 C CA  . LEU B 2 58  ? -16.366 -13.622 10.9    1   29.54  ? 54  LEU A CA  1 
ATOM   2543 C C   . LEU B 2 58  ? -16.866 -14.625 11.937  1   29.02  ? 54  LEU A C   1 
ATOM   2544 O O   . LEU B 2 58  ? -17.753 -15.395 11.622  1   31.56  ? 54  LEU A O   1 
ATOM   2545 C CB  . LEU B 2 58  ? -15.166 -14.164 10.119  1   26.66  ? 54  LEU A CB  1 
ATOM   2546 C CG  . LEU B 2 58  ? -14.669 -13.266 8.982   1   26.34  ? 54  LEU A CG  1 
ATOM   2547 C CD1 . LEU B 2 58  ? -13.459 -13.796 8.299   1   26.07  ? 54  LEU A CD1 1 
ATOM   2548 C CD2 . LEU B 2 58  ? -15.74  -13.023 7.966   1   25.8   ? 54  LEU A CD2 1 
ATOM   2549 N N   . LEU B 2 59  ? -16.299 -14.648 13.145  1   28.89  ? 55  LEU A N   1 
ATOM   2550 C CA  . LEU B 2 59  ? -16.758 -15.567 14.185  1   29.68  ? 55  LEU A CA  1 
ATOM   2551 C C   . LEU B 2 59  ? -18.158 -15.227 14.701  1   31.49  ? 55  LEU A C   1 
ATOM   2552 O O   . LEU B 2 59  ? -18.871 -16.093 15.206  1   31.21  ? 55  LEU A O   1 
ATOM   2553 C CB  . LEU B 2 59  ? -15.756 -15.658 15.333  1   27.25  ? 55  LEU A CB  1 
ATOM   2554 C CG  . LEU B 2 59  ? -14.535 -16.523 15.023  1   25.45  ? 55  LEU A CG  1 
ATOM   2555 C CD1 . LEU B 2 59  ? -13.67  -16.584 16.262  1   25.21  ? 55  LEU A CD1 1 
ATOM   2556 C CD2 . LEU B 2 59  ? -14.953 -17.901 14.49   1   22.72  ? 55  LEU A CD2 1 
ATOM   2557 N N   . LYS B 2 60  ? -18.535 -13.957 14.598  1   34.04  ? 56  LYS A N   1 
ATOM   2558 C CA  . LYS B 2 60  ? -19.839 -13.549 15.062  1   36.79  ? 56  LYS A CA  1 
ATOM   2559 C C   . LYS B 2 60  ? -20.942 -14.166 14.215  1   39.74  ? 56  LYS A C   1 
ATOM   2560 O O   . LYS B 2 60  ? -22.058 -14.293 14.704  1   52.61  ? 56  LYS A O   1 
ATOM   2561 C CB  . LYS B 2 60  ? -19.989 -12.033 14.957  1   38.14  ? 56  LYS A CB  1 
ATOM   2562 C CG  . LYS B 2 60  ? -19.181 -11.265 15.962  1   37.94  ? 56  LYS A CG  1 
ATOM   2563 C CD  . LYS B 2 60  ? -19.888 -9.948  16.258  1   41.04  ? 56  LYS A CD  1 
ATOM   2564 C CE  . LYS B 2 60  ? -21.235 -10.078 16.895  1   41.13  ? 56  LYS A CE  1 
ATOM   2565 N NZ  . LYS B 2 60  ? -21.735 -8.758  17.288  1   45.73  ? 56  LYS A NZ  1 
ATOM   2566 N N   A GLU B 2 61  ? -20.657 -14.518 12.959  0.5 39.1   ? 57  GLU A N   1 
ATOM   2567 N N   B GLU B 2 61  ? -20.631 -14.484 12.953  0.5 37.52  ? 57  GLU A N   1 
ATOM   2568 C CA  A GLU B 2 61  ? -21.68  -15.097 12.095  0.5 38.83  ? 57  GLU A CA  1 
ATOM   2569 C CA  B GLU B 2 61  ? -21.577 -15.086 12.02   0.5 36.01  ? 57  GLU A CA  1 
ATOM   2570 C C   A GLU B 2 61  ? -21.526 -16.618 11.96   0.5 37.18  ? 57  GLU A C   1 
ATOM   2571 C C   B GLU B 2 61  ? -21.617 -16.609 12.187  0.5 35.42  ? 57  GLU A C   1 
ATOM   2572 O O   A GLU B 2 61  ? -22.364 -17.261 11.327  0.5 38.48  ? 57  GLU A O   1 
ATOM   2573 O O   B GLU B 2 61  ? -22.68  -17.22  12.036  0.5 36.11  ? 57  GLU A O   1 
ATOM   2574 C CB  A GLU B 2 61  ? -21.733 -14.385 10.743  0.5 38.91  ? 57  GLU A CB  1 
ATOM   2575 C CB  B GLU B 2 61  ? -21.257 -14.677 10.58   0.5 33.66  ? 57  GLU A CB  1 
ATOM   2576 C CG  A GLU B 2 61  ? -22.36  -12.996 10.816  0.5 41.37  ? 57  GLU A CG  1 
ATOM   2577 C CG  B GLU B 2 61  ? -21.648 -13.235 10.281  0.5 33.26  ? 57  GLU A CG  1 
ATOM   2578 C CD  A GLU B 2 61  ? -23.687 -12.901 11.556  0.5 43.09  ? 57  GLU A CD  1 
ATOM   2579 C CD  B GLU B 2 61  ? -21.566 -12.814 8.831   0.5 33.57  ? 57  GLU A CD  1 
ATOM   2580 O OE1 A GLU B 2 61  ? -24.652 -13.631 11.215  0.5 42.21  ? 57  GLU A OE1 1 
ATOM   2581 O OE1 B GLU B 2 61  ? -20.974 -13.559 8.017   0.5 32.48  ? 57  GLU A OE1 1 
ATOM   2582 O OE2 A GLU B 2 61  ? -23.743 -12.075 12.492  0.5 44.19  ? 57  GLU A OE2 1 
ATOM   2583 O OE2 B GLU B 2 61  ? -22.14  -11.747 8.51    0.5 35.61  ? 57  GLU A OE2 1 
ATOM   2584 N N   . LEU B 2 62  ? -20.468 -17.203 12.544  1   33.53  ? 58  LEU A N   1 
ATOM   2585 C CA  . LEU B 2 62  ? -20.262 -18.64  12.455  1   30.1   ? 58  LEU A CA  1 
ATOM   2586 C C   . LEU B 2 62  ? -20.657 -19.331 13.753  1   33.72  ? 58  LEU A C   1 
ATOM   2587 O O   . LEU B 2 62  ? -19.796 -19.693 14.542  1   37.5   ? 58  LEU A O   1 
ATOM   2588 C CB  . LEU B 2 62  ? -18.806 -18.92  12.095  1   27.2   ? 58  LEU A CB  1 
ATOM   2589 C CG  . LEU B 2 62  ? -18.308 -18.327 10.77   1   26.09  ? 58  LEU A CG  1 
ATOM   2590 C CD1 . LEU B 2 62  ? -16.898 -18.71  10.503  1   24.17  ? 58  LEU A CD1 1 
ATOM   2591 C CD2 . LEU B 2 62  ? -19.119 -18.731 9.569   1   26.89  ? 58  LEU A CD2 1 
ATOM   2592 N N   . ASN B 2 63  ? -21.959 -19.567 13.951  1   39.14  ? 59  ASN A N   1 
ATOM   2593 C CA  . ASN B 2 63  ? -22.418 -20.334 15.1    1   39.92  ? 59  ASN A CA  1 
ATOM   2594 C C   . ASN B 2 63  ? -22.551 -21.783 14.663  1   33.26  ? 59  ASN A C   1 
ATOM   2595 O O   . ASN B 2 63  ? -23.401 -22.114 13.838  1   30.12  ? 59  ASN A O   1 
ATOM   2596 C CB  . ASN B 2 63  ? -23.558 -19.647 15.848  1   49.7   ? 59  ASN A CB  1 
ATOM   2597 C CG  . ASN B 2 63  ? -23.12  -18.259 16.265  1   67.15  ? 59  ASN A CG  1 
ATOM   2598 O OD1 . ASN B 2 63  ? -23.644 -17.239 15.795  1   78     ? 59  ASN A OD1 1 
ATOM   2599 N ND2 . ASN B 2 63  ? -22.09  -18.188 17.09   1   68.84  ? 59  ASN A ND2 1 
ATOM   2600 N N   . HIS B 2 64  ? -21.645 -22.612 15.193  1   27.98  ? 60  HIS A N   1 
ATOM   2601 C CA  . HIS B 2 64  ? -21.637 -24.031 14.891  1   25.77  ? 60  HIS A CA  1 
ATOM   2602 C C   . HIS B 2 64  ? -20.971 -24.797 16.034  1   24.39  ? 60  HIS A C   1 
ATOM   2603 O O   . HIS B 2 64  ? -20.05  -24.269 16.662  1   24.01  ? 60  HIS A O   1 
ATOM   2604 C CB  . HIS B 2 64  ? -20.937 -24.257 13.547  1   24.56  ? 60  HIS A CB  1 
ATOM   2605 C CG  . HIS B 2 64  ? -21.151 -25.62  13.008  1   23.98  ? 60  HIS A CG  1 
ATOM   2606 N ND1 . HIS B 2 64  ? -20.441 -26.721 13.449  1   23.77  ? 60  HIS A ND1 1 
ATOM   2607 C CD2 . HIS B 2 64  ? -22.031 -26.048 12.089  1   23.92  ? 60  HIS A CD2 1 
ATOM   2608 C CE1 . HIS B 2 64  ? -20.855 -27.784 12.771  1   26.05  ? 60  HIS A CE1 1 
ATOM   2609 N NE2 . HIS B 2 64  ? -21.842 -27.397 11.951  1   26.67  ? 60  HIS A NE2 1 
ATOM   2610 N N   . PRO B 2 65  ? -21.425 -26.042 16.34   1   23.13  ? 61  PRO A N   1 
ATOM   2611 C CA  . PRO B 2 65  ? -20.808 -26.88  17.378  1   22.31  ? 61  PRO A CA  1 
ATOM   2612 C C   . PRO B 2 65  ? -19.365 -27.34  17.177  1   21.96  ? 61  PRO A C   1 
ATOM   2613 O O   . PRO B 2 65  ? -18.755 -27.85  18.12   1   21.51  ? 61  PRO A O   1 
ATOM   2614 C CB  . PRO B 2 65  ? -21.753 -28.069 17.509  1   21.87  ? 61  PRO A CB  1 
ATOM   2615 C CG  . PRO B 2 65  ? -22.478 -28.118 16.182  1   21.91  ? 61  PRO A CG  1 
ATOM   2616 C CD  . PRO B 2 65  ? -22.625 -26.669 15.766  1   22.03  ? 61  PRO A CD  1 
ATOM   2617 N N   . ASN B 2 66  ? -18.834 -27.144 15.953  1   20.97  ? 62  ASN A N   1 
ATOM   2618 C CA  . ASN B 2 66  ? -17.464 -27.525 15.641  1   21.23  ? 62  ASN A CA  1 
ATOM   2619 C C   . ASN B 2 66  ? -16.666 -26.316 15.165  1   22.93  ? 62  ASN A C   1 
ATOM   2620 O O   . ASN B 2 66  ? -15.656 -26.476 14.47   1   24.49  ? 62  ASN A O   1 
ATOM   2621 C CB  . ASN B 2 66  ? -17.426 -28.612 14.58   1   20.46  ? 62  ASN A CB  1 
ATOM   2622 C CG  . ASN B 2 66  ? -18.136 -29.829 15.092  1   21.64  ? 62  ASN A CG  1 
ATOM   2623 O OD1 . ASN B 2 66  ? -19.279 -30.091 14.683  1   22.61  ? 62  ASN A OD1 1 
ATOM   2624 N ND2 . ASN B 2 66  ? -17.516 -30.499 16.059  1   21.11  ? 62  ASN A ND2 1 
ATOM   2625 N N   . ILE B 2 67  ? -17.146 -25.116 15.524  1   22.11  ? 63  ILE A N   1 
ATOM   2626 C CA  . ILE B 2 67  ? -16.36  -23.901 15.456  1   21.87  ? 63  ILE A CA  1 
ATOM   2627 C C   . ILE B 2 67  ? -16.332 -23.302 16.855  1   24.12  ? 63  ILE A C   1 
ATOM   2628 O O   . ILE B 2 67  ? -17.391 -23.144 17.466  1   26.13  ? 63  ILE A O   1 
ATOM   2629 C CB  . ILE B 2 67  ? -16.995 -22.938 14.441  1   22.03  ? 63  ILE A CB  1 
ATOM   2630 C CG1 . ILE B 2 67  ? -17.092 -23.593 13.052  1   20.4   ? 63  ILE A CG1 1 
ATOM   2631 C CG2 . ILE B 2 67  ? -16.274 -21.577 14.418  1   22.16  ? 63  ILE A CG2 1 
ATOM   2632 C CD1 . ILE B 2 67  ? -17.853 -22.763 12.031  1   20.2   ? 63  ILE A CD1 1 
ATOM   2633 N N   . VAL B 2 68  ? -15.127 -22.982 17.354  1   24.85  ? 64  VAL A N   1 
ATOM   2634 C CA  . VAL B 2 68  ? -14.976 -22.245 18.599  1   26.68  ? 64  VAL A CA  1 
ATOM   2635 C C   . VAL B 2 68  ? -15.919 -21.035 18.635  1   30.12  ? 64  VAL A C   1 
ATOM   2636 O O   . VAL B 2 68  ? -16.019 -20.246 17.689  1   32.03  ? 64  VAL A O   1 
ATOM   2637 C CB  . VAL B 2 68  ? -13.527 -21.792 18.803  1   26.38  ? 64  VAL A CB  1 
ATOM   2638 C CG1 . VAL B 2 68  ? -13.223 -20.562 17.938  1   25.86  ? 64  VAL A CG1 1 
ATOM   2639 C CG2 . VAL B 2 68  ? -13.259 -21.519 20.282  1   27.81  ? 64  VAL A CG2 1 
ATOM   2640 N N   . LYS B 2 69  ? -16.584 -20.877 19.78   1   32.45  ? 65  LYS A N   1 
ATOM   2641 C CA  . LYS B 2 69  ? -17.553 -19.815 19.993  1   32.63  ? 65  LYS A CA  1 
ATOM   2642 C C   . LYS B 2 69  ? -16.848 -18.627 20.639  1   31.26  ? 65  LYS A C   1 
ATOM   2643 O O   . LYS B 2 69  ? -16.344 -18.721 21.758  1   32.76  ? 65  LYS A O   1 
ATOM   2644 C CB  . LYS B 2 69  ? -18.654 -20.384 20.891  1   37.03  ? 65  LYS A CB  1 
ATOM   2645 C CG  . LYS B 2 69  ? -19.705 -19.422 21.373  1   45.65  ? 65  LYS A CG  1 
ATOM   2646 C CD  . LYS B 2 69  ? -20.93  -19.318 20.474  1   58.78  ? 65  LYS A CD  1 
ATOM   2647 C CE  . LYS B 2 69  ? -21.777 -18.085 20.743  1   66.42  ? 65  LYS A CE  1 
ATOM   2648 N NZ  . LYS B 2 69  ? -21.751 -17.106 19.652  1   70.9   ? 65  LYS A NZ  1 
ATOM   2649 N N   . LEU B 2 70  ? -16.789 -17.515 19.9    1   28.94  ? 66  LEU A N   1 
ATOM   2650 C CA  . LEU B 2 70  ? -16.525 -16.202 20.48   1   28.25  ? 66  LEU A CA  1 
ATOM   2651 C C   . LEU B 2 70  ? -17.737 -15.781 21.306  1   27.51  ? 66  LEU A C   1 
ATOM   2652 O O   . LEU B 2 70  ? -18.821 -15.59  20.759  1   26.39  ? 66  LEU A O   1 
ATOM   2653 C CB  . LEU B 2 70  ? -16.28  -15.194 19.357  1   27.63  ? 66  LEU A CB  1 
ATOM   2654 C CG  . LEU B 2 70  ? -16.048 -13.743 19.776  1   28.02  ? 66  LEU A CG  1 
ATOM   2655 C CD1 . LEU B 2 70  ? -14.787 -13.596 20.604  1   27.81  ? 66  LEU A CD1 1 
ATOM   2656 C CD2 . LEU B 2 70  ? -15.966 -12.904 18.499  1   28.05  ? 66  LEU A CD2 1 
ATOM   2657 N N   . LEU B 2 71  ? -17.542 -15.653 22.622  1   26.77  ? 67  LEU A N   1 
ATOM   2658 C CA  . LEU B 2 71  ? -18.669 -15.513 23.524  1   26.58  ? 67  LEU A CA  1 
ATOM   2659 C C   . LEU B 2 71  ? -18.998 -14.046 23.744  1   27.73  ? 67  LEU A C   1 
ATOM   2660 O O   . LEU B 2 71  ? -20.11  -13.745 24.167  1   28.67  ? 67  LEU A O   1 
ATOM   2661 C CB  . LEU B 2 71  ? -18.354 -16.198 24.848  1   26.63  ? 67  LEU A CB  1 
ATOM   2662 C CG  . LEU B 2 71  ? -18.348 -17.732 24.831  1   25.46  ? 67  LEU A CG  1 
ATOM   2663 C CD1 . LEU B 2 71  ? -17.921 -18.292 26.207  1   26.28  ? 67  LEU A CD1 1 
ATOM   2664 C CD2 . LEU B 2 71  ? -19.702 -18.288 24.419  1   23.67  ? 67  LEU A CD2 1 
ATOM   2665 N N   . ASP B 2 72  ? -18.004 -13.173 23.52   1   27.86  ? 68  ASP A N   1 
ATOM   2666 C CA  . ASP B 2 72  ? -18.076 -11.759 23.844  1   28.69  ? 68  ASP A CA  1 
ATOM   2667 C C   . ASP B 2 72  ? -16.818 -11.05  23.367  1   28.59  ? 68  ASP A C   1 
ATOM   2668 O O   . ASP B 2 72  ? -15.8   -11.691 23.157  1   27.58  ? 68  ASP A O   1 
ATOM   2669 C CB  . ASP B 2 72  ? -18.2   -11.505 25.333  1   31.05  ? 68  ASP A CB  1 
ATOM   2670 C CG  . ASP B 2 72  ? -18.831 -10.158 25.639  1   34.78  ? 68  ASP A CG  1 
ATOM   2671 O OD1 . ASP B 2 72  ? -18.97  -9.349  24.696  1   35.65  ? 68  ASP A OD1 1 
ATOM   2672 O OD2 . ASP B 2 72  ? -19.2   -9.925  26.8    1   38.04  ? 68  ASP A OD2 1 
ATOM   2673 N N   . VAL B 2 73  ? -16.901 -9.724  23.212  1   29.8   ? 69  VAL A N   1 
ATOM   2674 C CA  . VAL B 2 73  ? -15.745 -8.886  22.942  1   31.69  ? 69  VAL A CA  1 
ATOM   2675 C C   . VAL B 2 73  ? -15.794 -7.679  23.871  1   35.25  ? 69  VAL A C   1 
ATOM   2676 O O   . VAL B 2 73  ? -16.791 -6.987  23.876  1   35.7   ? 69  VAL A O   1 
ATOM   2677 C CB  . VAL B 2 73  ? -15.737 -8.39   21.489  1   30.92  ? 69  VAL A CB  1 
ATOM   2678 C CG1 . VAL B 2 73  ? -14.79  -7.199  21.343  1   32.89  ? 69  VAL A CG1 1 
ATOM   2679 C CG2 . VAL B 2 73  ? -15.446 -9.509  20.486  1   28.09  ? 69  VAL A CG2 1 
ATOM   2680 N N   . ILE B 2 74  ? -14.715 -7.401  24.615  1   38.69  ? 70  ILE A N   1 
ATOM   2681 C CA  . ILE B 2 74  ? -14.781 -6.385  25.656  1   43.96  ? 70  ILE A CA  1 
ATOM   2682 C C   . ILE B 2 74  ? -13.745 -5.305  25.391  1   49.2   ? 70  ILE A C   1 
ATOM   2683 O O   . ILE B 2 74  ? -12.574 -5.63   25.246  1   49.53  ? 70  ILE A O   1 
ATOM   2684 C CB  . ILE B 2 74  ? -14.607 -7.014  27.046  1   42.94  ? 70  ILE A CB  1 
ATOM   2685 C CG1 . ILE B 2 74  ? -15.849 -7.779  27.443  1   40.63  ? 70  ILE A CG1 1 
ATOM   2686 C CG2 . ILE B 2 74  ? -14.298 -5.911  28.049  1   46.06  ? 70  ILE A CG2 1 
ATOM   2687 C CD1 . ILE B 2 74  ? -15.613 -8.822  28.503  1   40.13  ? 70  ILE A CD1 1 
ATOM   2688 N N   . HIS B 2 75  ? -14.202 -4.051  25.282  1   55.97  ? 71  HIS A N   1 
ATOM   2689 C CA  . HIS B 2 75  ? -13.277 -2.941  25.104  1   67.92  ? 71  HIS A CA  1 
ATOM   2690 C C   . HIS B 2 75  ? -13.048 -2.25   26.448  1   71.66  ? 71  HIS A C   1 
ATOM   2691 O O   . HIS B 2 75  ? -13.995 -1.736  27.045  1   68.39  ? 71  HIS A O   1 
ATOM   2692 C CB  . HIS B 2 75  ? -13.711 -1.959  24.004  1   76.21  ? 71  HIS A CB  1 
ATOM   2693 C CG  . HIS B 2 75  ? -12.714 -0.84   23.871  1   90.36  ? 71  HIS A CG  1 
ATOM   2694 N ND1 . HIS B 2 75  ? -11.365 -1.132  23.881  1   96.35  ? 71  HIS A ND1 1 
ATOM   2695 C CD2 . HIS B 2 75  ? -12.802 0.506   23.774  1   92.18  ? 71  HIS A CD2 1 
ATOM   2696 C CE1 . HIS B 2 75  ? -10.675 -0.008  23.785  1   97.13  ? 71  HIS A CE1 1 
ATOM   2697 N NE2 . HIS B 2 75  ? -11.524 1       23.722  1   94.62  ? 71  HIS A NE2 1 
ATOM   2698 N N   . THR B 2 76  ? -11.786 -2.245  26.906  1   77.28  ? 72  THR A N   1 
ATOM   2699 C CA  . THR B 2 76  ? -11.462 -1.733  28.23   1   88.55  ? 72  THR A CA  1 
ATOM   2700 C C   . THR B 2 76  ? -10.162 -0.959  28.154  1   97.2   ? 72  THR A C   1 
ATOM   2701 O O   . THR B 2 76  ? -9.113  -1.542  28.398  1   104.21 ? 72  THR A O   1 
ATOM   2702 C CB  . THR B 2 76  ? -11.309 -2.821  29.3    1   92.83  ? 72  THR A CB  1 
ATOM   2703 O OG1 . THR B 2 76  ? -12.447 -3.665  29.256  1   104.95 ? 72  THR A OG1 1 
ATOM   2704 C CG2 . THR B 2 76  ? -11.232 -2.278  30.72   1   91.5   ? 72  THR A CG2 1 
ATOM   2705 N N   . GLU B 2 77  ? -10.248 0.342   27.851  1   105.04 ? 73  GLU A N   1 
ATOM   2706 C CA  . GLU B 2 77  ? -9.129  1.276   27.966  1   108.16 ? 73  GLU A CA  1 
ATOM   2707 C C   . GLU B 2 77  ? -7.911  0.803   27.16   1   103.3  ? 73  GLU A C   1 
ATOM   2708 O O   . GLU B 2 77  ? -6.996  0.188   27.715  1   106.58 ? 73  GLU A O   1 
ATOM   2709 C CB  . GLU B 2 77  ? -8.702  1.489   29.424  1   114.93 ? 73  GLU A CB  1 
ATOM   2710 C CG  . GLU B 2 77  ? -9.869  1.618   30.398  1   126.81 ? 73  GLU A CG  1 
ATOM   2711 C CD  . GLU B 2 77  ? -10.997 2.449   29.819  1   135.96 ? 73  GLU A CD  1 
ATOM   2712 O OE1 . GLU B 2 77  ? -10.814 3.678   29.662  1   138.2  ? 73  GLU A OE1 1 
ATOM   2713 O OE2 . GLU B 2 77  ? -12.042 1.85    29.486  1   136.77 ? 73  GLU A OE2 1 
ATOM   2714 N N   . ASN B 2 78  ? -7.882  1.106   25.852  1   94.37  ? 74  ASN A N   1 
ATOM   2715 C CA  . ASN B 2 78  ? -6.724  0.826   25.01   1   88.7   ? 74  ASN A CA  1 
ATOM   2716 C C   . ASN B 2 78  ? -6.393  -0.668  25.041  1   82.38  ? 74  ASN A C   1 
ATOM   2717 O O   . ASN B 2 78  ? -5.239  -1.055  24.885  1   85.69  ? 74  ASN A O   1 
ATOM   2718 C CB  . ASN B 2 78  ? -5.518  1.671   25.422  1   94.59  ? 74  ASN A CB  1 
ATOM   2719 C CG  . ASN B 2 78  ? -5.918  3.014   25.999  1   99.54  ? 74  ASN A CG  1 
ATOM   2720 O OD1 . ASN B 2 78  ? -5.565  3.351   27.137  1   99.49  ? 74  ASN A OD1 1 
ATOM   2721 N ND2 . ASN B 2 78  ? -6.667  3.798   25.239  1   102.07 ? 74  ASN A ND2 1 
ATOM   2722 N N   . LYS B 2 79  ? -7.413  -1.509  25.245  1   75.27  ? 75  LYS A N   1 
ATOM   2723 C CA  . LYS B 2 79  ? -7.259  -2.956  25.251  1   66.83  ? 75  LYS A CA  1 
ATOM   2724 C C   . LYS B 2 79  ? -8.549  -3.596  24.75   1   59.92  ? 75  LYS A C   1 
ATOM   2725 O O   . LYS B 2 79  ? -9.625  -3.18   25.16   1   60.99  ? 75  LYS A O   1 
ATOM   2726 C CB  . LYS B 2 79  ? -6.892  -3.417  26.665  1   68.4   ? 75  LYS A CB  1 
ATOM   2727 C CG  . LYS B 2 79  ? -5.522  -2.963  27.137  1   71.27  ? 75  LYS A CG  1 
ATOM   2728 C CD  . LYS B 2 79  ? -5.204  -3.421  28.557  1   79     ? 75  LYS A CD  1 
ATOM   2729 C CE  . LYS B 2 79  ? -3.849  -3.021  29.071  1   78.39  ? 75  LYS A CE  1 
ATOM   2730 N NZ  . LYS B 2 79  ? -3.631  -3.477  30.444  1   78.12  ? 75  LYS A NZ  1 
ATOM   2731 N N   . LEU B 2 80  ? -8.426  -4.575  23.852  1   53.93  ? 76  LEU A N   1 
ATOM   2732 C CA  . LEU B 2 80  ? -9.565  -5.362  23.41   1   49.78  ? 76  LEU A CA  1 
ATOM   2733 C C   . LEU B 2 80  ? -9.396  -6.808  23.891  1   47.05  ? 76  LEU A C   1 
ATOM   2734 O O   . LEU B 2 80  ? -8.311  -7.374  23.762  1   46.32  ? 76  LEU A O   1 
ATOM   2735 C CB  . LEU B 2 80  ? -9.602  -5.291  21.883  1   48.55  ? 76  LEU A CB  1 
ATOM   2736 C CG  . LEU B 2 80  ? -10.977 -5.425  21.23   1   45.87  ? 76  LEU A CG  1 
ATOM   2737 C CD1 . LEU B 2 80  ? -11.942 -4.398  21.896  1   47.09  ? 76  LEU A CD1 1 
ATOM   2738 C CD2 . LEU B 2 80  ? -10.751 -5.244  19.732  1   43.68  ? 76  LEU A CD2 1 
ATOM   2739 N N   . TYR B 2 81  ? -10.473 -7.402  24.435  1   44.13  ? 77  TYR A N   1 
ATOM   2740 C CA  . TYR B 2 81  ? -10.446 -8.744  25.011  1   41.36  ? 77  TYR A CA  1 
ATOM   2741 C C   . TYR B 2 81  ? -11.485 -9.634  24.333  1   38.39  ? 77  TYR A C   1 
ATOM   2742 O O   . TYR B 2 81  ? -12.676 -9.351  24.383  1   38.56  ? 77  TYR A O   1 
ATOM   2743 C CB  . TYR B 2 81  ? -10.809 -8.72   26.501  1   41.95  ? 77  TYR A CB  1 
ATOM   2744 C CG  . TYR B 2 81  ? -9.772  -8.185  27.476  1   44.22  ? 77  TYR A CG  1 
ATOM   2745 C CD1 . TYR B 2 81  ? -8.746  -8.999  27.94   1   44.8   ? 77  TYR A CD1 1 
ATOM   2746 C CD2 . TYR B 2 81  ? -9.831  -6.886  27.964  1   46.5   ? 77  TYR A CD2 1 
ATOM   2747 C CE1 . TYR B 2 81  ? -7.799  -8.525  28.837  1   47.52  ? 77  TYR A CE1 1 
ATOM   2748 C CE2 . TYR B 2 81  ? -8.896  -6.397  28.862  1   49.94  ? 77  TYR A CE2 1 
ATOM   2749 C CZ  . TYR B 2 81  ? -7.878  -7.224  29.312  1   50.84  ? 77  TYR A CZ  1 
ATOM   2750 O OH  . TYR B 2 81  ? -6.976  -6.74   30.23   1   54.78  ? 77  TYR A OH  1 
ATOM   2751 N N   . LEU B 2 82  ? -11.043 -10.729 23.719  1   35.96  ? 78  LEU A N   1 
ATOM   2752 C CA  . LEU B 2 82  ? -11.961 -11.7   23.139  1   33.84  ? 78  LEU A CA  1 
ATOM   2753 C C   . LEU B 2 82  ? -12.217 -12.836 24.122  1   32.58  ? 78  LEU A C   1 
ATOM   2754 O O   . LEU B 2 82  ? -11.295 -13.56  24.497  1   32.94  ? 78  LEU A O   1 
ATOM   2755 C CB  . LEU B 2 82  ? -11.436 -12.285 21.829  1   31.6   ? 78  LEU A CB  1 
ATOM   2756 C CG  . LEU B 2 82  ? -10.762 -11.299 20.882  1   32.36  ? 78  LEU A CG  1 
ATOM   2757 C CD1 . LEU B 2 82  ? -10.856 -11.848 19.492  1   30.38  ? 78  LEU A CD1 1 
ATOM   2758 C CD2 . LEU B 2 82  ? -11.404 -9.939  20.997  1   34.08  ? 78  LEU A CD2 1 
ATOM   2759 N N   . VAL B 2 83  ? -13.489 -13.01  24.469  1   30.81  ? 79  VAL A N   1 
ATOM   2760 C CA  . VAL B 2 83  ? -13.908 -14.086 25.335  1   31.03  ? 79  VAL A CA  1 
ATOM   2761 C C   . VAL B 2 83  ? -14.327 -15.261 24.449  1   29.98  ? 79  VAL A C   1 
ATOM   2762 O O   . VAL B 2 83  ? -15.299 -15.15  23.706  1   29.71  ? 79  VAL A O   1 
ATOM   2763 C CB  . VAL B 2 83  ? -15.058 -13.598 26.24   1   30.92  ? 79  VAL A CB  1 
ATOM   2764 C CG1 . VAL B 2 83  ? -15.475 -14.665 27.261  1   30.06  ? 79  VAL A CG1 1 
ATOM   2765 C CG2 . VAL B 2 83  ? -14.721 -12.269 26.907  1   32.03  ? 79  VAL A CG2 1 
ATOM   2766 N N   . PHE B 2 84  ? -13.604 -16.392 24.518  1   30.07  ? 80  PHE A N   1 
ATOM   2767 C CA  . PHE B 2 84  ? -14.02  -17.565 23.755  1   30     ? 80  PHE A CA  1 
ATOM   2768 C C   . PHE B 2 84  ? -14.461 -18.713 24.663  1   31.99  ? 80  PHE A C   1 
ATOM   2769 O O   . PHE B 2 84  ? -14.087 -18.781 25.837  1   35.13  ? 80  PHE A O   1 
ATOM   2770 C CB  . PHE B 2 84  ? -12.912 -18.14  22.889  1   27.94  ? 80  PHE A CB  1 
ATOM   2771 C CG  . PHE B 2 84  ? -12.419 -17.282 21.742  1   28.44  ? 80  PHE A CG  1 
ATOM   2772 C CD1 . PHE B 2 84  ? -11.453 -16.305 21.945  1   29.68  ? 80  PHE A CD1 1 
ATOM   2773 C CD2 . PHE B 2 84  ? -12.851 -17.527 20.437  1   27.76  ? 80  PHE A CD2 1 
ATOM   2774 C CE1 . PHE B 2 84  ? -10.966 -15.578 20.861  1   30.51  ? 80  PHE A CE1 1 
ATOM   2775 C CE2 . PHE B 2 84  ? -12.346 -16.799 19.365  1   26.86  ? 80  PHE A CE2 1 
ATOM   2776 C CZ  . PHE B 2 84  ? -11.417 -15.82  19.574  1   27.99  ? 80  PHE A CZ  1 
ATOM   2777 N N   . GLU B 2 85  ? -15.219 -19.634 24.058  1   31.33  ? 81  GLU A N   1 
ATOM   2778 C CA  . GLU B 2 85  ? -15.578 -20.861 24.804  1   31.83  ? 81  GLU A CA  1 
ATOM   2779 C C   . GLU B 2 85  ? -14.253 -21.586 25.054  1   33.83  ? 81  GLU A C   1 
ATOM   2780 O O   . GLU B 2 85  ? -13.39  -21.607 24.144  1   37.31  ? 81  GLU A O   1 
ATOM   2781 C CB  . GLU B 2 85  ? -16.589 -21.711 24.033  1   29.92  ? 81  GLU A CB  1 
ATOM   2782 C CG  . GLU B 2 85  ? -16.052 -22.242 22.708  1   31.61  ? 81  GLU A CG  1 
ATOM   2783 C CD  . GLU B 2 85  ? -16.773 -23.462 22.167  1   34.62  ? 81  GLU A CD  1 
ATOM   2784 O OE1 . GLU B 2 85  ? -16.978 -24.418 22.942  1   39.96  ? 81  GLU A OE1 1 
ATOM   2785 O OE2 . GLU B 2 85  ? -17.126 -23.456 20.97   1   28.45  ? 81  GLU A OE2 1 
ATOM   2786 N N   . PHE B 2 86  ? -14.081 -22.127 26.25   1   33.02  ? 82  PHE A N   1 
ATOM   2787 C CA  . PHE B 2 86  ? -12.817 -22.754 26.606  1   30.91  ? 82  PHE A CA  1 
ATOM   2788 C C   . PHE B 2 86  ? -12.827 -24.224 26.201  1   29.78  ? 82  PHE A C   1 
ATOM   2789 O O   . PHE B 2 86  ? -13.813 -24.92  26.354  1   28.9   ? 82  PHE A O   1 
ATOM   2790 C CB  . PHE B 2 86  ? -12.542 -22.669 28.106  1   30.83  ? 82  PHE A CB  1 
ATOM   2791 C CG  . PHE B 2 86  ? -11.392 -23.548 28.543  1   32.25  ? 82  PHE A CG  1 
ATOM   2792 C CD1 . PHE B 2 86  ? -10.086 -23.151 28.331  1   34.5   ? 82  PHE A CD1 1 
ATOM   2793 C CD2 . PHE B 2 86  ? -11.611 -24.786 29.143  1   32.75  ? 82  PHE A CD2 1 
ATOM   2794 C CE1 . PHE B 2 86  ? -9.034  -23.973 28.738  1   36.06  ? 82  PHE A CE1 1 
ATOM   2795 C CE2 . PHE B 2 86  ? -10.557 -25.592 29.539  1   32.6   ? 82  PHE A CE2 1 
ATOM   2796 C CZ  . PHE B 2 86  ? -9.27   -25.193 29.337  1   33.65  ? 82  PHE A CZ  1 
ATOM   2797 N N   . LEU B 2 87  ? -11.691 -24.684 25.694  1   31.51  ? 83  LEU A N   1 
ATOM   2798 C CA  . LEU B 2 87  ? -11.443 -26.075 25.373  1   31.54  ? 83  LEU A CA  1 
ATOM   2799 C C   . LEU B 2 87  ? -10.074 -26.45  25.911  1   32.25  ? 83  LEU A C   1 
ATOM   2800 O O   . LEU B 2 87  ? -9.208  -25.589 26.041  1   33.11  ? 83  LEU A O   1 
ATOM   2801 C CB  . LEU B 2 87  ? -11.508 -26.251 23.861  1   30.26  ? 83  LEU A CB  1 
ATOM   2802 C CG  . LEU B 2 87  ? -12.926 -26.306 23.281  1   30.96  ? 83  LEU A CG  1 
ATOM   2803 C CD1 . LEU B 2 87  ? -13.404 -24.995 22.732  1   31.14  ? 83  LEU A CD1 1 
ATOM   2804 C CD2 . LEU B 2 87  ? -13.11  -27.398 22.247  1   34.15  ? 83  LEU A CD2 1 
ATOM   2805 N N   . HIS B 2 88  ? -9.905  -27.739 26.2    1   33.16  ? 84  HIS A N   1 
ATOM   2806 C CA  . HIS B 2 88  ? -8.855  -28.179 27.102  1   37.65  ? 84  HIS A CA  1 
ATOM   2807 C C   . HIS B 2 88  ? -7.498  -28.253 26.398  1   37.02  ? 84  HIS A C   1 
ATOM   2808 O O   . HIS B 2 88  ? -6.47   -28.087 27.047  1   40.08  ? 84  HIS A O   1 
ATOM   2809 C CB  . HIS B 2 88  ? -9.243  -29.513 27.747  1   42.15  ? 84  HIS A CB  1 
ATOM   2810 C CG  . HIS B 2 88  ? -10.551 -29.463 28.476  1   50.76  ? 84  HIS A CG  1 
ATOM   2811 N ND1 . HIS B 2 88  ? -11.769 -29.265 27.84   1   51.99  ? 84  HIS A ND1 1 
ATOM   2812 C CD2 . HIS B 2 88  ? -10.836 -29.559 29.808  1   52.73  ? 84  HIS A CD2 1 
ATOM   2813 C CE1 . HIS B 2 88  ? -12.751 -29.274 28.746  1   52.63  ? 84  HIS A CE1 1 
ATOM   2814 N NE2 . HIS B 2 88  ? -12.21  -29.454 29.954  1   52.69  ? 84  HIS A NE2 1 
ATOM   2815 N N   . GLN B 2 89  ? -7.482  -28.471 25.075  1   34.36  ? 85  GLN A N   1 
ATOM   2816 C CA  . GLN B 2 89  ? -6.277  -28.93  24.393  1   33.79  ? 85  GLN A CA  1 
ATOM   2817 C C   . GLN B 2 89  ? -6.425  -28.863 22.866  1   30.56  ? 85  GLN A C   1 
ATOM   2818 O O   . GLN B 2 89  ? -7.52   -28.78  22.332  1   27.99  ? 85  GLN A O   1 
ATOM   2819 C CB  . GLN B 2 89  ? -6.065  -30.344 24.918  1   36.83  ? 85  GLN A CB  1 
ATOM   2820 C CG  . GLN B 2 89  ? -4.918  -31.106 24.287  1   45.48  ? 85  GLN A CG  1 
ATOM   2821 C CD  . GLN B 2 89  ? -4.48   -32.218 25.208  1   61.11  ? 85  GLN A CD  1 
ATOM   2822 O OE1 . GLN B 2 89  ? -4.026  -31.953 26.33   1   74.15  ? 85  GLN A OE1 1 
ATOM   2823 N NE2 . GLN B 2 89  ? -4.644  -33.464 24.769  1   62.71  ? 85  GLN A NE2 1 
ATOM   2824 N N   . ASP B 2 90  ? -5.293  -28.88  22.156  1   31.23  ? 86  ASP A N   1 
ATOM   2825 C CA  . ASP B 2 90  ? -5.243  -28.938 20.703  1   28.78  ? 86  ASP A CA  1 
ATOM   2826 C C   . ASP B 2 90  ? -4.933  -30.35  20.23   1   28.32  ? 86  ASP A C   1 
ATOM   2827 O O   . ASP B 2 90  ? -4.301  -31.157 20.916  1   28.76  ? 86  ASP A O   1 
ATOM   2828 C CB  . ASP B 2 90  ? -4.228  -27.968 20.119  1   29.72  ? 86  ASP A CB  1 
ATOM   2829 C CG  . ASP B 2 90  ? -2.774  -28.185 20.517  1   32.91  ? 86  ASP A CG  1 
ATOM   2830 O OD1 . ASP B 2 90  ? -2.183  -29.15  20.045  1   36.1   ? 86  ASP A OD1 1 
ATOM   2831 O OD2 . ASP B 2 90  ? -2.237  -27.398 21.308  1   36.11  ? 86  ASP A OD2 1 
ATOM   2832 N N   . LEU B 2 91  ? -5.344  -30.61  18.998  1   27.35  ? 87  LEU A N   1 
ATOM   2833 C CA  . LEU B 2 91  ? -5.166  -31.924 18.423  1   29.09  ? 87  LEU A CA  1 
ATOM   2834 C C   . LEU B 2 91  ? -3.681  -32.274 18.435  1   33.18  ? 87  LEU A C   1 
ATOM   2835 O O   . LEU B 2 91  ? -3.34   -33.437 18.628  1   39.24  ? 87  LEU A O   1 
ATOM   2836 C CB  . LEU B 2 91  ? -5.786  -31.985 17.03   1   26.64  ? 87  LEU A CB  1 
ATOM   2837 C CG  . LEU B 2 91  ? -5.676  -33.331 16.306  1   26.66  ? 87  LEU A CG  1 
ATOM   2838 C CD1 . LEU B 2 91  ? -6.25   -34.387 17.204  1   26.86  ? 87  LEU A CD1 1 
ATOM   2839 C CD2 . LEU B 2 91  ? -6.375  -33.337 14.946  1   24.46  ? 87  LEU A CD2 1 
ATOM   2840 N N   . LYS B 2 92  ? -2.805  -31.28  18.254  1   32.86  ? 88  LYS A N   1 
ATOM   2841 C CA  . LYS B 2 92  ? -1.37   -31.537 18.2    1   35.1   ? 88  LYS A CA  1 
ATOM   2842 C C   . LYS B 2 92  ? -0.885  -32.116 19.532  1   40.34  ? 88  LYS A C   1 
ATOM   2843 O O   . LYS B 2 92  ? -0.152  -33.094 19.533  1   45.47  ? 88  LYS A O   1 
ATOM   2844 C CB  . LYS B 2 92  ? -0.578  -30.331 17.689  1   33.02  ? 88  LYS A CB  1 
ATOM   2845 C CG  . LYS B 2 92  ? 0.934   -30.366 17.843  1   35.8   ? 88  LYS A CG  1 
ATOM   2846 C CD  . LYS B 2 92  ? 1.754   -31.597 17.452  1   39.79  ? 88  LYS A CD  1 
ATOM   2847 C CE  . LYS B 2 92  ? 1.762   -31.929 15.993  1   43.19  ? 88  LYS A CE  1 
ATOM   2848 N NZ  . LYS B 2 92  ? 2.281   -33.27  15.68   1   40.84  ? 88  LYS A NZ  1 
ATOM   2849 N N   . LYS B 2 93  ? -1.306  -31.555 20.668  1   42.99  ? 89  LYS A N   1 
ATOM   2850 C CA  . LYS B 2 93  ? -0.832  -32.079 21.936  1   48.05  ? 89  LYS A CA  1 
ATOM   2851 C C   . LYS B 2 93  ? -1.392  -33.483 22.153  1   46.83  ? 89  LYS A C   1 
ATOM   2852 O O   . LYS B 2 93  ? -0.685  -34.346 22.661  1   47.98  ? 89  LYS A O   1 
ATOM   2853 C CB  . LYS B 2 93  ? -1.129  -31.145 23.11   1   56.25  ? 89  LYS A CB  1 
ATOM   2854 C CG  . LYS B 2 93  ? -0.373  -29.815 23.082  1   66.42  ? 89  LYS A CG  1 
ATOM   2855 C CD  . LYS B 2 93  ? -0.209  -29.153 24.453  1   71.2   ? 89  LYS A CD  1 
ATOM   2856 C CE  . LYS B 2 93  ? -0.453  -27.668 24.435  1   65.3   ? 89  LYS A CE  1 
ATOM   2857 N NZ  . LYS B 2 93  ? -1.892  -27.396 24.348  1   62.5   ? 89  LYS A NZ  1 
ATOM   2858 N N   . PHE B 2 94  ? -2.637  -33.713 21.717  1   44.16  ? 90  PHE A N   1 
ATOM   2859 C CA  . PHE B 2 94  ? -3.308  -34.994 21.901  1   41.85  ? 90  PHE A CA  1 
ATOM   2860 C C   . PHE B 2 94  ? -2.633  -36.082 21.057  1   42.55  ? 90  PHE A C   1 
ATOM   2861 O O   . PHE B 2 94  ? -2.485  -37.216 21.503  1   44.5   ? 90  PHE A O   1 
ATOM   2862 C CB  . PHE B 2 94  ? -4.797  -34.851 21.577  1   38.17  ? 90  PHE A CB  1 
ATOM   2863 C CG  . PHE B 2 94  ? -5.58   -36.142 21.686  1   38.63  ? 90  PHE A CG  1 
ATOM   2864 C CD1 . PHE B 2 94  ? -5.59   -36.872 22.871  1   41.24  ? 90  PHE A CD1 1 
ATOM   2865 C CD2 . PHE B 2 94  ? -6.265  -36.657 20.589  1   37.14  ? 90  PHE A CD2 1 
ATOM   2866 C CE1 . PHE B 2 94  ? -6.28   -38.079 22.959  1   39.82  ? 90  PHE A CE1 1 
ATOM   2867 C CE2 . PHE B 2 94  ? -6.964  -37.858 20.677  1   36.5   ? 90  PHE A CE2 1 
ATOM   2868 C CZ  . PHE B 2 94  ? -6.981  -38.557 21.868  1   38.04  ? 90  PHE A CZ  1 
ATOM   2869 N N   . MET B 2 95  ? -2.203  -35.734 19.838  1   38.83  ? 91  MET A N   1 
ATOM   2870 C CA  . MET B 2 95  ? -1.504  -36.681 18.997  1   37.52  ? 91  MET A CA  1 
ATOM   2871 C C   . MET B 2 95  ? -0.229  -37.116 19.708  1   42.15  ? 91  MET A C   1 
ATOM   2872 O O   . MET B 2 95  ? 0.125   -38.296 19.728  1   47.87  ? 91  MET A O   1 
ATOM   2873 C CB  . MET B 2 95  ? -1.176  -36.06  17.643  1   37.4   ? 91  MET A CB  1 
ATOM   2874 C CG  . MET B 2 95  ? -2.348  -35.987 16.682  1   40.36  ? 91  MET A CG  1 
ATOM   2875 S SD  . MET B 2 95  ? -1.977  -35.288 15.052  1   47.27  ? 91  MET A SD  1 
ATOM   2876 C CE  . MET B 2 95  ? -1.116  -33.763 15.446  1   42.27  ? 91  MET A CE  1 
ATOM   2877 N N   . ASP B 2 96  ? 0.459   -36.151 20.315  1   43.39  ? 92  ASP A N   1 
ATOM   2878 C CA  . ASP B 2 96  ? 1.7     -36.426 21.02   1   45.83  ? 92  ASP A CA  1 
ATOM   2879 C C   . ASP B 2 96  ? 1.415   -37.34  22.205  1   46.88  ? 92  ASP A C   1 
ATOM   2880 O O   . ASP B 2 96  ? 2.159   -38.281 22.434  1   50.92  ? 92  ASP A O   1 
ATOM   2881 C CB  . ASP B 2 96  ? 2.39    -35.151 21.484  1   48.59  ? 92  ASP A CB  1 
ATOM   2882 C CG  . ASP B 2 96  ? 2.818   -34.163 20.406  1   49.22  ? 92  ASP A CG  1 
ATOM   2883 O OD1 . ASP B 2 96  ? 2.855   -34.556 19.197  1   45.78  ? 92  ASP A OD1 1 
ATOM   2884 O OD2 . ASP B 2 96  ? 3.07    -32.992 20.792  1   49.76  ? 92  ASP A OD2 1 
ATOM   2885 N N   . ALA B 2 97  ? 0.335   -37.06  22.948  1   45.72  ? 93  ALA A N   1 
ATOM   2886 C CA  . ALA B 2 97  ? -0.063  -37.867 24.094  1   45.74  ? 93  ALA A CA  1 
ATOM   2887 C C   . ALA B 2 97  ? -0.41   -39.304 23.685  1   46.95  ? 93  ALA A C   1 
ATOM   2888 O O   . ALA B 2 97  ? -0.287  -40.22  24.488  1   49.39  ? 93  ALA A O   1 
ATOM   2889 C CB  . ALA B 2 97  ? -1.208  -37.194 24.809  1   42.79  ? 93  ALA A CB  1 
ATOM   2890 N N   . SER B 2 98  ? -0.837  -39.504 22.432  1   47.13  ? 94  SER A N   1 
ATOM   2891 C CA  . SER B 2 98  ? -1.263  -40.802 21.935  1   47.81  ? 94  SER A CA  1 
ATOM   2892 C C   . SER B 2 98  ? -0.129  -41.558 21.246  1   52.09  ? 94  SER A C   1 
ATOM   2893 O O   . SER B 2 98  ? -0.405  -42.279 20.291  1   55.08  ? 94  SER A O   1 
ATOM   2894 C CB  . SER B 2 98  ? -2.381  -40.633 20.956  1   42.73  ? 94  SER A CB  1 
ATOM   2895 O OG  . SER B 2 98  ? -3.442  -39.928 21.56   1   43.36  ? 94  SER A OG  1 
ATOM   2896 N N   . ALA B 2 99  ? 1.12    -41.442 21.714  1   54.29  ? 95  ALA A N   1 
ATOM   2897 C CA  . ALA B 2 99  ? 2.229   -41.935 20.902  1   57.67  ? 95  ALA A CA  1 
ATOM   2898 C C   . ALA B 2 99  ? 2.234   -43.464 20.825  1   62.37  ? 95  ALA A C   1 
ATOM   2899 O O   . ALA B 2 99  ? 2.348   -44.024 19.739  1   63.1   ? 95  ALA A O   1 
ATOM   2900 C CB  . ALA B 2 99  ? 3.562   -41.391 21.378  1   57.04  ? 95  ALA A CB  1 
ATOM   2901 N N   . LEU B 2 100 ? 2.108   -44.128 21.982  1   65.53  ? 96  LEU A N   1 
ATOM   2902 C CA  . LEU B 2 100 ? 2.307   -45.566 22.095  1   66.37  ? 96  LEU A CA  1 
ATOM   2903 C C   . LEU B 2 100 ? 1.036   -46.332 21.737  1   65.55  ? 96  LEU A C   1 
ATOM   2904 O O   . LEU B 2 100 ? 1.098   -47.541 21.504  1   67.85  ? 96  LEU A O   1 
ATOM   2905 C CB  . LEU B 2 100 ? 2.738   -45.91  23.521  1   70.96  ? 96  LEU A CB  1 
ATOM   2906 C CG  . LEU B 2 100 ? 4.24    -45.997 23.808  1   72.37  ? 96  LEU A CG  1 
ATOM   2907 C CD1 . LEU B 2 100 ? 5.008   -44.71  23.498  1   69.74  ? 96  LEU A CD1 1 
ATOM   2908 C CD2 . LEU B 2 100 ? 4.401   -46.387 25.276  1   74.51  ? 96  LEU A CD2 1 
ATOM   2909 N N   . THR B 2 101 ? -0.108  -45.631 21.763  1   61.63  ? 97  THR A N   1 
ATOM   2910 C CA  . THR B 2 101 ? -1.402  -46.22  21.452  1   61.84  ? 97  THR A CA  1 
ATOM   2911 C C   . THR B 2 101 ? -1.721  -45.955 19.98   1   60.49  ? 97  THR A C   1 
ATOM   2912 O O   . THR B 2 101 ? -2.199  -46.839 19.265  1   65.21  ? 97  THR A O   1 
ATOM   2913 C CB  . THR B 2 101 ? -2.53   -45.671 22.338  1   61.16  ? 97  THR A CB  1 
ATOM   2914 O OG1 . THR B 2 101 ? -2.628  -44.259 22.178  1   56.33  ? 97  THR A OG1 1 
ATOM   2915 C CG2 . THR B 2 101 ? -2.356  -45.946 23.818  1   62.13  ? 97  THR A CG2 1 
ATOM   2916 N N   . GLY B 2 102 ? -1.47   -44.715 19.545  1   52.63  ? 98  GLY A N   1 
ATOM   2917 C CA  . GLY B 2 102 ? -2.111  -44.179 18.36   1   45.29  ? 98  GLY A CA  1 
ATOM   2918 C C   . GLY B 2 102 ? -3.473  -43.623 18.755  1   43.48  ? 98  GLY A C   1 
ATOM   2919 O O   . GLY B 2 102 ? -3.92   -43.853 19.878  1   43.67  ? 98  GLY A O   1 
ATOM   2920 N N   . ILE B 2 103 ? -4.109  -42.868 17.85   1   39.82  ? 99  ILE A N   1 
ATOM   2921 C CA  . ILE B 2 103 ? -5.471  -42.426 18.09   1   36.55  ? 99  ILE A CA  1 
ATOM   2922 C C   . ILE B 2 103 ? -6.397  -43.545 17.633  1   36.48  ? 99  ILE A C   1 
ATOM   2923 O O   . ILE B 2 103 ? -6.371  -43.927 16.481  1   38.21  ? 99  ILE A O   1 
ATOM   2924 C CB  . ILE B 2 103 ? -5.776  -41.128 17.325  1   34.31  ? 99  ILE A CB  1 
ATOM   2925 C CG1 . ILE B 2 103 ? -4.807  -40     17.697  1   33.71  ? 99  ILE A CG1 1 
ATOM   2926 C CG2 . ILE B 2 103 ? -7.232  -40.716 17.551  1   32.48  ? 99  ILE A CG2 1 
ATOM   2927 C CD1 . ILE B 2 103 ? -5.105  -38.686 16.988  1   31.29  ? 99  ILE A CD1 1 
ATOM   2928 N N   . PRO B 2 104 ? -7.28   -44.106 18.473  1   36.34  ? 100 PRO A N   1 
ATOM   2929 C CA  . PRO B 2 104 ? -8.094  -45.24  18.031  1   35.92  ? 100 PRO A CA  1 
ATOM   2930 C C   . PRO B 2 104 ? -8.936  -44.75  16.862  1   33.32  ? 100 PRO A C   1 
ATOM   2931 O O   . PRO B 2 104 ? -9.238  -43.563 16.768  1   31.69  ? 100 PRO A O   1 
ATOM   2932 C CB  . PRO B 2 104 ? -8.948  -45.573 19.25   1   36.89  ? 100 PRO A CB  1 
ATOM   2933 C CG  . PRO B 2 104 ? -8.266  -44.883 20.399  1   37.02  ? 100 PRO A CG  1 
ATOM   2934 C CD  . PRO B 2 104 ? -7.593  -43.645 19.829  1   35.88  ? 100 PRO A CD  1 
ATOM   2935 N N   . LEU B 2 105 ? -9.321  -45.676 15.985  1   33.69  ? 101 LEU A N   1 
ATOM   2936 C CA  . LEU B 2 105 ? -9.925  -45.339 14.701  1   31.12  ? 101 LEU A CA  1 
ATOM   2937 C C   . LEU B 2 105 ? -11.242 -44.613 14.903  1   30.02  ? 101 LEU A C   1 
ATOM   2938 O O   . LEU B 2 105 ? -11.514 -43.698 14.155  1   28.04  ? 101 LEU A O   1 
ATOM   2939 C CB  . LEU B 2 105 ? -10.173 -46.589 13.864  1   31.99  ? 101 LEU A CB  1 
ATOM   2940 C CG  . LEU B 2 105 ? -10.871 -46.353 12.524  1   30.13  ? 101 LEU A CG  1 
ATOM   2941 C CD1 . LEU B 2 105 ? -10.045 -45.497 11.606  1   30.86  ? 101 LEU A CD1 1 
ATOM   2942 C CD2 . LEU B 2 105 ? -11.295 -47.644 11.858  1   27.26  ? 101 LEU A CD2 1 
ATOM   2943 N N   . PRO B 2 106 ? -12.127 -45.029 15.845  1   31.85  ? 102 PRO A N   1 
ATOM   2944 C CA  . PRO B 2 106 ? -13.371 -44.301 16.092  1   31.62  ? 102 PRO A CA  1 
ATOM   2945 C C   . PRO B 2 106 ? -13.105 -42.822 16.314  1   31.02  ? 102 PRO A C   1 
ATOM   2946 O O   . PRO B 2 106 ? -13.935 -42.007 15.944  1   33.45  ? 102 PRO A O   1 
ATOM   2947 C CB  . PRO B 2 106 ? -13.966 -44.959 17.343  1   32.34  ? 102 PRO A CB  1 
ATOM   2948 C CG  . PRO B 2 106 ? -13.377 -46.35  17.364  1   33.47  ? 102 PRO A CG  1 
ATOM   2949 C CD  . PRO B 2 106 ? -12.031 -46.243 16.672  1   33.22  ? 102 PRO A CD  1 
ATOM   2950 N N   . LEU B 2 107 ? -11.946 -42.486 16.89   1   30.82  ? 103 LEU A N   1 
ATOM   2951 C CA  . LEU B 2 107 ? -11.663 -41.114 17.255  1   30.65  ? 103 LEU A CA  1 
ATOM   2952 C C   . LEU B 2 107 ? -11.149 -40.334 16.047  1   29.37  ? 103 LEU A C   1 
ATOM   2953 O O   . LEU B 2 107 ? -11.591 -39.211 15.795  1   28.07  ? 103 LEU A O   1 
ATOM   2954 C CB  . LEU B 2 107 ? -10.68  -41.109 18.417  1   33.92  ? 103 LEU A CB  1 
ATOM   2955 C CG  . LEU B 2 107 ? -10.884 -40.018 19.481  1   36.74  ? 103 LEU A CG  1 
ATOM   2956 C CD1 . LEU B 2 107 ? -12.325 -39.648 19.788  1   35.37  ? 103 LEU A CD1 1 
ATOM   2957 C CD2 . LEU B 2 107 ? -10.209 -40.516 20.771  1   41.47  ? 103 LEU A CD2 1 
ATOM   2958 N N   . ILE B 2 108 ? -10.228 -40.936 15.289  1   28.61  ? 104 ILE A N   1 
ATOM   2959 C CA  . ILE B 2 108 ? -9.783  -40.355 14.035  1   27.48  ? 104 ILE A CA  1 
ATOM   2960 C C   . ILE B 2 108 ? -11.01  -40.078 13.168  1   28.59  ? 104 ILE A C   1 
ATOM   2961 O O   . ILE B 2 108 ? -11.061 -39.123 12.394  1   30.86  ? 104 ILE A O   1 
ATOM   2962 C CB  . ILE B 2 108 ? -8.821  -41.334 13.345  1   28.39  ? 104 ILE A CB  1 
ATOM   2963 C CG1 . ILE B 2 108 ? -7.576  -41.597 14.179  1   28.86  ? 104 ILE A CG1 1 
ATOM   2964 C CG2 . ILE B 2 108 ? -8.479  -40.894 11.921  1   26.94  ? 104 ILE A CG2 1 
ATOM   2965 C CD1 . ILE B 2 108 ? -6.543  -42.441 13.46   1   28.96  ? 104 ILE A CD1 1 
ATOM   2966 N N   . LYS B 2 109 ? -12.022 -40.925 13.306  1   28.78  ? 105 LYS A N   1 
ATOM   2967 C CA  . LYS B 2 109 ? -13.132 -40.933 12.379  1   28.58  ? 105 LYS A CA  1 
ATOM   2968 C C   . LYS B 2 109 ? -14.148 -39.88  12.814  1   28.72  ? 105 LYS A C   1 
ATOM   2969 O O   . LYS B 2 109 ? -14.641 -39.107 11.995  1   27.55  ? 105 LYS A O   1 
ATOM   2970 C CB  . LYS B 2 109 ? -13.655 -42.372 12.374  1   29.62  ? 105 LYS A CB  1 
ATOM   2971 C CG  . LYS B 2 109 ? -14.623 -42.713 11.271  1   29.13  ? 105 LYS A CG  1 
ATOM   2972 C CD  . LYS B 2 109 ? -15.059 -44.167 11.368  1   31.64  ? 105 LYS A CD  1 
ATOM   2973 C CE  . LYS B 2 109 ? -14.205 -45.138 10.635  1   32.1   ? 105 LYS A CE  1 
ATOM   2974 N NZ  . LYS B 2 109 ? -15.035 -46.321 10.376  1   34.85  ? 105 LYS A NZ  1 
ATOM   2975 N N   . SER B 2 110 ? -14.46  -39.871 14.116  1   29.85  ? 106 SER A N   1 
ATOM   2976 C CA  . SER B 2 110 ? -15.293 -38.848 14.717  1   29.51  ? 106 SER A CA  1 
ATOM   2977 C C   . SER B 2 110 ? -14.675 -37.464 14.491  1   29.59  ? 106 SER A C   1 
ATOM   2978 O O   . SER B 2 110 ? -15.379 -36.515 14.136  1   31.78  ? 106 SER A O   1 
ATOM   2979 C CB  . SER B 2 110 ? -15.495 -39.134 16.167  1   29.63  ? 106 SER A CB  1 
ATOM   2980 O OG  . SER B 2 110 ? -16.027 -38.002 16.848  1   30.18  ? 106 SER A OG  1 
ATOM   2981 N N   . TYR B 2 111 ? -13.354 -37.346 14.674  1   28.31  ? 107 TYR A N   1 
ATOM   2982 C CA  . TYR B 2 111 ? -12.719 -36.044 14.57   1   26.27  ? 107 TYR A CA  1 
ATOM   2983 C C   . TYR B 2 111 ? -12.777 -35.551 13.126  1   25.11  ? 107 TYR A C   1 
ATOM   2984 O O   . TYR B 2 111 ? -13.114 -34.392 12.906  1   23.3   ? 107 TYR A O   1 
ATOM   2985 C CB  . TYR B 2 111 ? -11.285 -36.025 15.108  1   26.02  ? 107 TYR A CB  1 
ATOM   2986 C CG  . TYR B 2 111 ? -11.133 -35.932 16.618  1   25.36  ? 107 TYR A CG  1 
ATOM   2987 C CD1 . TYR B 2 111 ? -12.219 -35.623 17.433  1   24.98  ? 107 TYR A CD1 1 
ATOM   2988 C CD2 . TYR B 2 111 ? -9.898  -36.153 17.227  1   24.65  ? 107 TYR A CD2 1 
ATOM   2989 C CE1 . TYR B 2 111 ? -12.074 -35.535 18.813  1   25.81  ? 107 TYR A CE1 1 
ATOM   2990 C CE2 . TYR B 2 111 ? -9.758  -36.071 18.604  1   25.41  ? 107 TYR A CE2 1 
ATOM   2991 C CZ  . TYR B 2 111 ? -10.844 -35.758 19.403  1   25.62  ? 107 TYR A CZ  1 
ATOM   2992 O OH  . TYR B 2 111 ? -10.78  -35.646 20.763  1   27.53  ? 107 TYR A OH  1 
ATOM   2993 N N   . LEU B 2 112 ? -12.448 -36.409 12.149  1   24.88  ? 108 LEU A N   1 
ATOM   2994 C CA  . LEU B 2 112 ? -12.467 -35.924 10.778  1   26.2   ? 108 LEU A CA  1 
ATOM   2995 C C   . LEU B 2 112 ? -13.889 -35.476 10.429  1   29.07  ? 108 LEU A C   1 
ATOM   2996 O O   . LEU B 2 112 ? -14.113 -34.384 9.884   1   27.41  ? 108 LEU A O   1 
ATOM   2997 C CB  . LEU B 2 112 ? -11.973 -36.998 9.815   1   26.45  ? 108 LEU A CB  1 
ATOM   2998 C CG  . LEU B 2 112 ? -11.795 -36.586 8.348   1   24.51  ? 108 LEU A CG  1 
ATOM   2999 C CD1 . LEU B 2 112 ? -10.751 -35.483 8.207   1   21.96  ? 108 LEU A CD1 1 
ATOM   3000 C CD2 . LEU B 2 112 ? -11.415 -37.827 7.536   1   24.39  ? 108 LEU A CD2 1 
ATOM   3001 N N   . PHE B 2 113 ? -14.862 -36.334 10.779  1   30.23  ? 109 PHE A N   1 
ATOM   3002 C CA  . PHE B 2 113 ? -16.264 -36.071 10.503  1   28.54  ? 109 PHE A CA  1 
ATOM   3003 C C   . PHE B 2 113 ? -16.684 -34.7   11.024  1   27.88  ? 109 PHE A C   1 
ATOM   3004 O O   . PHE B 2 113 ? -17.464 -34.006 10.368  1   31.01  ? 109 PHE A O   1 
ATOM   3005 C CB  . PHE B 2 113 ? -17.151 -37.116 11.166  1   28.01  ? 109 PHE A CB  1 
ATOM   3006 C CG  . PHE B 2 113 ? -18.564 -37.141 10.608  1   28.76  ? 109 PHE A CG  1 
ATOM   3007 C CD1 . PHE B 2 113 ? -18.79  -37.223 9.233   1   27.96  ? 109 PHE A CD1 1 
ATOM   3008 C CD2 . PHE B 2 113 ? -19.661 -37.106 11.463  1   29.14  ? 109 PHE A CD2 1 
ATOM   3009 C CE1 . PHE B 2 113 ? -20.077 -37.285 8.724   1   28.11  ? 109 PHE A CE1 1 
ATOM   3010 C CE2 . PHE B 2 113 ? -20.949 -37.153 10.951  1   29.88  ? 109 PHE A CE2 1 
ATOM   3011 C CZ  . PHE B 2 113 ? -21.153 -37.251 9.587   1   29.69  ? 109 PHE A CZ  1 
ATOM   3012 N N   . GLN B 2 114 ? -16.211 -34.345 12.226  1   26.49  ? 110 GLN A N   1 
ATOM   3013 C CA  . GLN B 2 114 ? -16.596 -33.092 12.869  1   25.45  ? 110 GLN A CA  1 
ATOM   3014 C C   . GLN B 2 114 ? -15.93  -31.905 12.154  1   23.36  ? 110 GLN A C   1 
ATOM   3015 O O   . GLN B 2 114 ? -16.561 -30.877 11.955  1   20.57  ? 110 GLN A O   1 
ATOM   3016 C CB  . GLN B 2 114 ? -16.256 -33.131 14.36   1   23.99  ? 110 GLN A CB  1 
ATOM   3017 C CG  . GLN B 2 114 ? -17.219 -33.914 15.234  1   25.92  ? 110 GLN A CG  1 
ATOM   3018 C CD  . GLN B 2 114 ? -16.735 -34.073 16.667  1   28.2   ? 110 GLN A CD  1 
ATOM   3019 O OE1 . GLN B 2 114 ? -16.842 -33.164 17.508  1   27.94  ? 110 GLN A OE1 1 
ATOM   3020 N NE2 . GLN B 2 114 ? -16.222 -35.261 16.971  1   28.32  ? 110 GLN A NE2 1 
ATOM   3021 N N   . LEU B 2 115 ? -14.64  -32.054 11.807  1   23.25  ? 111 LEU A N   1 
ATOM   3022 C CA  . LEU B 2 115 ? -13.849 -31.025 11.156  1   23.49  ? 111 LEU A CA  1 
ATOM   3023 C C   . LEU B 2 115 ? -14.501 -30.643 9.834   1   23.43  ? 111 LEU A C   1 
ATOM   3024 O O   . LEU B 2 115 ? -14.595 -29.465 9.487   1   22.3   ? 111 LEU A O   1 
ATOM   3025 C CB  . LEU B 2 115 ? -12.426 -31.54  10.947  1   23.5   ? 111 LEU A CB  1 
ATOM   3026 C CG  . LEU B 2 115 ? -11.592 -31.756 12.217  1   22.83  ? 111 LEU A CG  1 
ATOM   3027 C CD1 . LEU B 2 115 ? -10.298 -32.497 11.897  1   21.41  ? 111 LEU A CD1 1 
ATOM   3028 C CD2 . LEU B 2 115 ? -11.287 -30.44  12.914  1   20.61  ? 111 LEU A CD2 1 
ATOM   3029 N N   . LEU B 2 116 ? -14.941 -31.677 9.115   1   25.51  ? 112 LEU A N   1 
ATOM   3030 C CA  . LEU B 2 116 ? -15.633 -31.513 7.852   1   25.94  ? 112 LEU A CA  1 
ATOM   3031 C C   . LEU B 2 116 ? -16.943 -30.776 8.083   1   27.12  ? 112 LEU A C   1 
ATOM   3032 O O   . LEU B 2 116 ? -17.238 -29.857 7.329   1   32.12  ? 112 LEU A O   1 
ATOM   3033 C CB  . LEU B 2 116 ? -15.876 -32.868 7.201   1   25.02  ? 112 LEU A CB  1 
ATOM   3034 C CG  . LEU B 2 116 ? -14.647 -33.538 6.584   1   23.19  ? 112 LEU A CG  1 
ATOM   3035 C CD1 . LEU B 2 116 ? -14.969 -34.979 6.313   1   22.45  ? 112 LEU A CD1 1 
ATOM   3036 C CD2 . LEU B 2 116 ? -14.182 -32.832 5.312   1   22.65  ? 112 LEU A CD2 1 
ATOM   3037 N N   . GLN B 2 117 ? -17.704 -31.157 9.115   1   25.09  ? 113 GLN A N   1 
ATOM   3038 C CA  . GLN B 2 117 ? -18.957 -30.471 9.383   1   25.56  ? 113 GLN A CA  1 
ATOM   3039 C C   . GLN B 2 117 ? -18.729 -28.962 9.501   1   24.91  ? 113 GLN A C   1 
ATOM   3040 O O   . GLN B 2 117 ? -19.477 -28.175 8.913   1   25.41  ? 113 GLN A O   1 
ATOM   3041 C CB  . GLN B 2 117 ? -19.627 -30.972 10.654  1   26.62  ? 113 GLN A CB  1 
ATOM   3042 C CG  . GLN B 2 117 ? -20.316 -32.317 10.494  1   30.08  ? 113 GLN A CG  1 
ATOM   3043 C CD  . GLN B 2 117 ? -21.149 -32.679 11.706  1   31.68  ? 113 GLN A CD  1 
ATOM   3044 O OE1 . GLN B 2 117 ? -21.897 -31.852 12.254  1   31.19  ? 113 GLN A OE1 1 
ATOM   3045 N NE2 . GLN B 2 117 ? -21.003 -33.92  12.144  1   30.79  ? 113 GLN A NE2 1 
ATOM   3046 N N   . GLY B 2 118 ? -17.688 -28.578 10.258  1   22.56  ? 114 GLY A N   1 
ATOM   3047 C CA  . GLY B 2 118 ? -17.441 -27.198 10.632  1   20.93  ? 114 GLY A CA  1 
ATOM   3048 C C   . GLY B 2 118 ? -16.85  -26.419 9.466   1   21.63  ? 114 GLY A C   1 
ATOM   3049 O O   . GLY B 2 118 ? -17.118 -25.232 9.281   1   19.35  ? 114 GLY A O   1 
ATOM   3050 N N   . LEU B 2 119 ? -16.016 -27.12  8.69    1   23.27  ? 115 LEU A N   1 
ATOM   3051 C CA  . LEU B 2 119 ? -15.45  -26.529 7.499   1   22.28  ? 115 LEU A CA  1 
ATOM   3052 C C   . LEU B 2 119 ? -16.569 -26.276 6.493   1   23.34  ? 115 LEU A C   1 
ATOM   3053 O O   . LEU B 2 119 ? -16.606 -25.242 5.835   1   23.68  ? 115 LEU A O   1 
ATOM   3054 C CB  . LEU B 2 119 ? -14.361 -27.433 6.936   1   20.6   ? 115 LEU A CB  1 
ATOM   3055 C CG  . LEU B 2 119 ? -13.669 -26.876 5.689   1   20.98  ? 115 LEU A CG  1 
ATOM   3056 C CD1 . LEU B 2 119 ? -13.005 -25.533 5.983   1   19.67  ? 115 LEU A CD1 1 
ATOM   3057 C CD2 . LEU B 2 119 ? -12.672 -27.888 5.162   1   21.13  ? 115 LEU A CD2 1 
ATOM   3058 N N   . ALA B 2 120 ? -17.469 -27.243 6.334   1   23.73  ? 116 ALA A N   1 
ATOM   3059 C CA  . ALA B 2 120 ? -18.48  -27.072 5.31    1   25.91  ? 116 ALA A CA  1 
ATOM   3060 C C   . ALA B 2 120 ? -19.323 -25.858 5.677   1   27.75  ? 116 ALA A C   1 
ATOM   3061 O O   . ALA B 2 120 ? -19.842 -25.156 4.816   1   29.44  ? 116 ALA A O   1 
ATOM   3062 C CB  . ALA B 2 120 ? -19.322 -28.32  5.218   1   26.56  ? 116 ALA A CB  1 
ATOM   3063 N N   . PHE B 2 121 ? -19.503 -25.652 6.981   1   28.66  ? 117 PHE A N   1 
ATOM   3064 C CA  . PHE B 2 121 ? -20.337 -24.575 7.471   1   26.67  ? 117 PHE A CA  1 
ATOM   3065 C C   . PHE B 2 121 ? -19.661 -23.248 7.148   1   25.59  ? 117 PHE A C   1 
ATOM   3066 O O   . PHE B 2 121 ? -20.321 -22.382 6.61    1   26.27  ? 117 PHE A O   1 
ATOM   3067 C CB  . PHE B 2 121 ? -20.66  -24.81  8.942   1   25.42  ? 117 PHE A CB  1 
ATOM   3068 C CG  . PHE B 2 121 ? -21.532 -23.721 9.534   1   27.47  ? 117 PHE A CG  1 
ATOM   3069 C CD1 . PHE B 2 121 ? -20.989 -22.502 9.933   1   28.25  ? 117 PHE A CD1 1 
ATOM   3070 C CD2 . PHE B 2 121 ? -22.894 -23.917 9.691   1   28.15  ? 117 PHE A CD2 1 
ATOM   3071 C CE1 . PHE B 2 121 ? -21.787 -21.509 10.48   1   27.76  ? 117 PHE A CE1 1 
ATOM   3072 C CE2 . PHE B 2 121 ? -23.691 -22.918 10.22   1   27.56  ? 117 PHE A CE2 1 
ATOM   3073 C CZ  . PHE B 2 121 ? -23.138 -21.722 10.608  1   27.81  ? 117 PHE A CZ  1 
ATOM   3074 N N   . CYS B 2 122 ? -18.352 -23.123 7.409   1   25.67  ? 118 CYS A N   1 
ATOM   3075 C CA  . CYS B 2 122 ? -17.597 -21.933 7.016   1   28.54  ? 118 CYS A CA  1 
ATOM   3076 C C   . CYS B 2 122 ? -17.804 -21.643 5.52    1   29.6   ? 118 CYS A C   1 
ATOM   3077 O O   . CYS B 2 122 ? -18.194 -20.547 5.113   1   32.7   ? 118 CYS A O   1 
ATOM   3078 C CB  . CYS B 2 122 ? -16.097 -22.054 7.292   1   26.54  ? 118 CYS A CB  1 
ATOM   3079 S SG  . CYS B 2 122 ? -15.655 -22.34  9.029   1   28.64  ? 118 CYS A SG  1 
ATOM   3080 N N   . HIS B 2 123 ? -17.579 -22.653 4.703   1   26.73  ? 119 HIS A N   1 
ATOM   3081 C CA  . HIS B 2 123 ? -17.652 -22.509 3.23    1   25.56  ? 119 HIS A CA  1 
ATOM   3082 C C   . HIS B 2 123 ? -19.052 -22.117 2.766   1   26.71  ? 119 HIS A C   1 
ATOM   3083 O O   . HIS B 2 123 ? -19.179 -21.463 1.722   1   26.13  ? 119 HIS A O   1 
ATOM   3084 C CB  . HIS B 2 123 ? -17.164 -23.833 2.651   1   25.17  ? 119 HIS A CB  1 
ATOM   3085 C CG  . HIS B 2 123 ? -15.696 -24.047 2.765   1   25.94  ? 119 HIS A CG  1 
ATOM   3086 N ND1 . HIS B 2 123 ? -15.095 -25.24  2.435   1   26.9   ? 119 HIS A ND1 1 
ATOM   3087 C CD2 . HIS B 2 123 ? -14.713 -23.228 3.143   1   27.29  ? 119 HIS A CD2 1 
ATOM   3088 C CE1 . HIS B 2 123 ? -13.792 -25.131 2.618   1   28.45  ? 119 HIS A CE1 1 
ATOM   3089 N NE2 . HIS B 2 123 ? -13.538 -23.917 3.047   1   27.91  ? 119 HIS A NE2 1 
ATOM   3090 N N   . SER B 2 124 ? -20.074 -22.525 3.511   1   27.37  ? 120 SER A N   1 
ATOM   3091 C CA  . SER B 2 124 ? -21.478 -22.218 3.148   1   28.46  ? 120 SER A CA  1 
ATOM   3092 C C   . SER B 2 124 ? -21.817 -20.804 3.616   1   28.2   ? 120 SER A C   1 
ATOM   3093 O O   . SER B 2 124 ? -22.812 -20.248 3.149   1   31.24  ? 120 SER A O   1 
ATOM   3094 C CB  . SER B 2 124 ? -22.391 -23.224 3.752   1   29.12  ? 120 SER A CB  1 
ATOM   3095 O OG  . SER B 2 124 ? -21.914 -24.547 3.57    1   31.65  ? 120 SER A OG  1 
ATOM   3096 N N   . HIS B 2 125 ? -20.973 -20.235 4.471   1   26.29  ? 121 HIS A N   1 
ATOM   3097 C CA  . HIS B 2 125 ? -21.182 -18.856 4.976   1   26.46  ? 121 HIS A CA  1 
ATOM   3098 C C   . HIS B 2 125 ? -20.102 -17.95  4.377   1   28.61  ? 121 HIS A C   1 
ATOM   3099 O O   . HIS B 2 125 ? -19.866 -16.897 4.985   1   30.66  ? 121 HIS A O   1 
ATOM   3100 C CB  . HIS B 2 125 ? -21.348 -18.887 6.497   1   23.77  ? 121 HIS A CB  1 
ATOM   3101 C CG  . HIS B 2 125 ? -22.552 -19.641 6.919   1   25.34  ? 121 HIS A CG  1 
ATOM   3102 N ND1 . HIS B 2 125 ? -22.598 -21.015 6.93    1   25.98  ? 121 HIS A ND1 1 
ATOM   3103 C CD2 . HIS B 2 125 ? -23.748 -19.226 7.317   1   27.23  ? 121 HIS A CD2 1 
ATOM   3104 C CE1 . HIS B 2 125 ? -23.796 -21.402 7.322   1   26.5   ? 121 HIS A CE1 1 
ATOM   3105 N NE2 . HIS B 2 125 ? -24.508 -20.331 7.569   1   28.21  ? 121 HIS A NE2 1 
ATOM   3106 N N   . ARG B 2 126 ? -19.483 -18.35  3.261   1   28.8   ? 122 ARG A N   1 
ATOM   3107 C CA  . ARG B 2 126 ? -18.525 -17.507 2.492   1   29.66  ? 122 ARG A CA  1 
ATOM   3108 C C   . ARG B 2 126 ? -17.207 -17.28  3.251   1   29.42  ? 122 ARG A C   1 
ATOM   3109 O O   . ARG B 2 126 ? -16.599 -16.218 3.09    1   29.68  ? 122 ARG A O   1 
ATOM   3110 C CB  . ARG B 2 126 ? -19.288 -16.268 1.999   1   31.28  ? 122 ARG A CB  1 
ATOM   3111 C CG  . ARG B 2 126 ? -18.965 -14.824 2.353   1   33.16  ? 122 ARG A CG  1 
ATOM   3112 C CD  . ARG B 2 126 ? -20.17  -14.035 2.794   1   36.79  ? 122 ARG A CD  1 
ATOM   3113 N NE  . ARG B 2 126 ? -19.812 -13.136 3.893   1   43.5   ? 122 ARG A NE  1 
ATOM   3114 C CZ  . ARG B 2 126 ? -20.308 -13.243 5.112   1   46.2   ? 122 ARG A CZ  1 
ATOM   3115 N NH1 . ARG B 2 126 ? -19.941 -14.242 5.89    1   40.98  ? 122 ARG A NH1 1 
ATOM   3116 N NH2 . ARG B 2 126 ? -21.182 -12.357 5.543   1   45.32  ? 122 ARG A NH2 1 
ATOM   3117 N N   . VAL B 2 127 ? -16.723 -18.289 3.972   1   26.52  ? 123 VAL A N   1 
ATOM   3118 C CA  . VAL B 2 127 ? -15.491 -18.045 4.778   1   26.17  ? 123 VAL A CA  1 
ATOM   3119 C C   . VAL B 2 127 ? -14.425 -19.119 4.537   1   26.57  ? 123 VAL A C   1 
ATOM   3120 O O   . VAL B 2 127 ? -14.752 -20.299 4.664   1   30.74  ? 123 VAL A O   1 
ATOM   3121 C CB  . VAL B 2 127 ? -15.737 -17.861 6.295   1   23.61  ? 123 VAL A CB  1 
ATOM   3122 C CG1 . VAL B 2 127 ? -14.443 -17.793 7.09    1   22.4   ? 123 VAL A CG1 1 
ATOM   3123 C CG2 . VAL B 2 127 ? -16.603 -16.647 6.596   1   23.28  ? 123 VAL A CG2 1 
ATOM   3124 N N   . LEU B 2 128 ? -13.238 -18.714 4.09    1   24.46  ? 124 LEU A N   1 
ATOM   3125 C CA  . LEU B 2 128 ? -12.09  -19.599 4.065   1   23.4   ? 124 LEU A CA  1 
ATOM   3126 C C   . LEU B 2 128 ? -11.339 -19.496 5.386   1   25.34  ? 124 LEU A C   1 
ATOM   3127 O O   . LEU B 2 128 ? -11.162 -18.392 5.937   1   26.85  ? 124 LEU A O   1 
ATOM   3128 C CB  . LEU B 2 128 ? -11.132 -19.212 2.945   1   23.07  ? 124 LEU A CB  1 
ATOM   3129 C CG  . LEU B 2 128 ? -11.691 -19.245 1.53    1   23.46  ? 124 LEU A CG  1 
ATOM   3130 C CD1 . LEU B 2 128 ? -10.579 -19.01  0.565   1   23.41  ? 124 LEU A CD1 1 
ATOM   3131 C CD2 . LEU B 2 128 ? -12.297 -20.591 1.253   1   24.49  ? 124 LEU A CD2 1 
ATOM   3132 N N   . HIS B 2 129 ? -10.804 -20.647 5.816   1   23.48  ? 125 HIS A N   1 
ATOM   3133 C CA  . HIS B 2 129 ? -10.078 -20.695 7.07    1   24.32  ? 125 HIS A CA  1 
ATOM   3134 C C   . HIS B 2 129 ? -8.634  -20.263 6.842   1   25.36  ? 125 HIS A C   1 
ATOM   3135 O O   . HIS B 2 129 ? -8.156  -19.321 7.473   1   27.65  ? 125 HIS A O   1 
ATOM   3136 C CB  . HIS B 2 129 ? -10.183 -22.073 7.726   1   23.6   ? 125 HIS A CB  1 
ATOM   3137 C CG  . HIS B 2 129 ? -9.591  -22.032 9.087   1   23.86  ? 125 HIS A CG  1 
ATOM   3138 N ND1 . HIS B 2 129 ? -8.23   -22.039 9.28    1   25.43  ? 125 HIS A ND1 1 
ATOM   3139 C CD2 . HIS B 2 129 ? -10.13  -21.923 10.294  1   23.72  ? 125 HIS A CD2 1 
ATOM   3140 C CE1 . HIS B 2 129 ? -7.974  -21.993 10.577  1   26.01  ? 125 HIS A CE1 1 
ATOM   3141 N NE2 . HIS B 2 129 ? -9.118  -21.914 11.213  1   25.37  ? 125 HIS A NE2 1 
ATOM   3142 N N   . ARG B 2 130 ? -7.95   -21.012 5.975   1   24.87  ? 126 ARG A N   1 
ATOM   3143 C CA  . ARG B 2 130 ? -6.634  -20.691 5.446   1   26.03  ? 126 ARG A CA  1 
ATOM   3144 C C   . ARG B 2 130 ? -5.531  -20.871 6.488   1   28.17  ? 126 ARG A C   1 
ATOM   3145 O O   . ARG B 2 130 ? -4.426  -20.374 6.256   1   32.39  ? 126 ARG A O   1 
ATOM   3146 C CB  . ARG B 2 130 ? -6.598  -19.267 4.874   1   26.44  ? 126 ARG A CB  1 
ATOM   3147 C CG  . ARG B 2 130 ? -7.602  -18.999 3.76    1   26.12  ? 126 ARG A CG  1 
ATOM   3148 C CD  . ARG B 2 130 ? -7.255  -17.775 2.945   1   25.93  ? 126 ARG A CD  1 
ATOM   3149 N NE  . ARG B 2 130 ? -7.318  -16.621 3.839   1   26.77  ? 126 ARG A NE  1 
ATOM   3150 C CZ  . ARG B 2 130 ? -6.859  -15.407 3.581   1   27.5   ? 126 ARG A CZ  1 
ATOM   3151 N NH1 . ARG B 2 130 ? -6.361  -15.088 2.399   1   27.58  ? 126 ARG A NH1 1 
ATOM   3152 N NH2 . ARG B 2 130 ? -6.937  -14.505 4.535   1   28.01  ? 126 ARG A NH2 1 
ATOM   3153 N N   . ASP B 2 131 ? -5.804  -21.557 7.614   1   26.48  ? 127 ASP A N   1 
ATOM   3154 C CA  . ASP B 2 131 ? -4.716  -21.997 8.478   1   28.2   ? 127 ASP A CA  1 
ATOM   3155 C C   . ASP B 2 131 ? -5.114  -23.21  9.302   1   28.74  ? 127 ASP A C   1 
ATOM   3156 O O   . ASP B 2 131 ? -4.809  -23.275 10.489  1   33.36  ? 127 ASP A O   1 
ATOM   3157 C CB  . ASP B 2 131 ? -4.181  -20.946 9.441   1   29.85  ? 127 ASP A CB  1 
ATOM   3158 C CG  . ASP B 2 131 ? -2.775  -21.236 9.953   1   33.58  ? 127 ASP A CG  1 
ATOM   3159 O OD1 . ASP B 2 131 ? -2.111  -22.174 9.419   1   39.23  ? 127 ASP A OD1 1 
ATOM   3160 O OD2 . ASP B 2 131 ? -2.354  -20.548 10.885  1   34.25  ? 127 ASP A OD2 1 
ATOM   3161 N N   . LEU B 2 132 ? -5.75   -24.187 8.657   1   26.74  ? 128 LEU A N   1 
ATOM   3162 C CA  . LEU B 2 132 ? -6.049  -25.455 9.301   1   26.31  ? 128 LEU A CA  1 
ATOM   3163 C C   . LEU B 2 132 ? -4.757  -26.229 9.585   1   27.65  ? 128 LEU A C   1 
ATOM   3164 O O   . LEU B 2 132 ? -3.83   -26.299 8.764   1   32.33  ? 128 LEU A O   1 
ATOM   3165 C CB  . LEU B 2 132 ? -6.994  -26.206 8.369   1   25.29  ? 128 LEU A CB  1 
ATOM   3166 C CG  . LEU B 2 132 ? -8.384  -25.581 8.208   1   25.04  ? 128 LEU A CG  1 
ATOM   3167 C CD1 . LEU B 2 132 ? -9.237  -26.47  7.305   1   26.83  ? 128 LEU A CD1 1 
ATOM   3168 C CD2 . LEU B 2 132 ? -9.052  -25.355 9.562   1   23.08  ? 128 LEU A CD2 1 
ATOM   3169 N N   . LYS B 2 133 ? -4.694  -26.796 10.788  1   25.35  ? 129 LYS A N   1 
ATOM   3170 C CA  . LYS B 2 133 ? -3.534  -27.516 11.285  1   25.08  ? 129 LYS A CA  1 
ATOM   3171 C C   . LYS B 2 133 ? -3.775  -27.87  12.752  1   26.69  ? 129 LYS A C   1 
ATOM   3172 O O   . LYS B 2 133 ? -4.545  -27.192 13.45   1   25.24  ? 129 LYS A O   1 
ATOM   3173 C CB  . LYS B 2 133 ? -2.248  -26.692 11.194  1   26.45  ? 129 LYS A CB  1 
ATOM   3174 C CG  . LYS B 2 133 ? -2.256  -25.366 11.928  1   28.19  ? 129 LYS A CG  1 
ATOM   3175 C CD  . LYS B 2 133 ? -0.863  -24.848 12.228  1   29.87  ? 129 LYS A CD  1 
ATOM   3176 C CE  . LYS B 2 133 ? -0.897  -23.473 12.845  1   33.24  ? 129 LYS A CE  1 
ATOM   3177 N NZ  . LYS B 2 133 ? 0.353   -22.738 12.609  1   34.82  ? 129 LYS A NZ  1 
ATOM   3178 N N   . PRO B 2 134 ? -3.138  -28.955 13.268  1   27.4   ? 130 PRO A N   1 
ATOM   3179 C CA  . PRO B 2 134 ? -3.529  -29.517 14.562  1   26.94  ? 130 PRO A CA  1 
ATOM   3180 C C   . PRO B 2 134 ? -3.518  -28.506 15.706  1   29.37  ? 130 PRO A C   1 
ATOM   3181 O O   . PRO B 2 134 ? -4.364  -28.585 16.598  1   33.21  ? 130 PRO A O   1 
ATOM   3182 C CB  . PRO B 2 134 ? -2.53   -30.654 14.739  1   25.86  ? 130 PRO A CB  1 
ATOM   3183 C CG  . PRO B 2 134 ? -2.178  -31.039 13.328  1   23.75  ? 130 PRO A CG  1 
ATOM   3184 C CD  . PRO B 2 134 ? -2.049  -29.712 12.626  1   24.81  ? 130 PRO A CD  1 
ATOM   3185 N N   . GLN B 2 135 ? -2.609  -27.523 15.642  1   28.84  ? 131 GLN A N   1 
ATOM   3186 C CA  . GLN B 2 135 ? -2.466  -26.548 16.714  1   28.79  ? 131 GLN A CA  1 
ATOM   3187 C C   . GLN B 2 135 ? -3.684  -25.628 16.761  1   26.78  ? 131 GLN A C   1 
ATOM   3188 O O   . GLN B 2 135 ? -3.912  -24.967 17.759  1   27.24  ? 131 GLN A O   1 
ATOM   3189 C CB  . GLN B 2 135 ? -1.184  -25.724 16.573  1   32.33  ? 131 GLN A CB  1 
ATOM   3190 C CG  . GLN B 2 135 ? 0.135   -26.501 16.565  1   33.85  ? 131 GLN A CG  1 
ATOM   3191 C CD  . GLN B 2 135 ? 0.332   -27.376 15.338  1   34.73  ? 131 GLN A CD  1 
ATOM   3192 O OE1 . GLN B 2 135 ? -0.554  -27.559 14.495  1   33.82  ? 131 GLN A OE1 1 
ATOM   3193 N NE2 . GLN B 2 135 ? 1.503   -27.974 15.231  1   37.06  ? 131 GLN A NE2 1 
ATOM   3194 N N   . ASN B 2 136 ? -4.465  -25.572 15.681  1   25.61  ? 132 ASN A N   1 
ATOM   3195 C CA  . ASN B 2 136 ? -5.616  -24.685 15.629  1   26.16  ? 132 ASN A CA  1 
ATOM   3196 C C   . ASN B 2 136 ? -6.93   -25.472 15.639  1   27.25  ? 132 ASN A C   1 
ATOM   3197 O O   . ASN B 2 136 ? -7.978  -24.96  15.243  1   28.19  ? 132 ASN A O   1 
ATOM   3198 C CB  . ASN B 2 136 ? -5.558  -23.785 14.4    1   27.32  ? 132 ASN A CB  1 
ATOM   3199 C CG  . ASN B 2 136 ? -4.428  -22.783 14.41   1   30.76  ? 132 ASN A CG  1 
ATOM   3200 O OD1 . ASN B 2 136 ? -4.03   -22.278 15.463  1   34.4   ? 132 ASN A OD1 1 
ATOM   3201 N ND2 . ASN B 2 136 ? -3.934  -22.415 13.238  1   31.46  ? 132 ASN A ND2 1 
ATOM   3202 N N   . LEU B 2 137 ? -6.886  -26.721 16.107  1   27.67  ? 133 LEU A N   1 
ATOM   3203 C CA  . LEU B 2 137 ? -8.085  -27.529 16.235  1   25.78  ? 133 LEU A CA  1 
ATOM   3204 C C   . LEU B 2 137 ? -8.192  -27.936 17.691  1   27.75  ? 133 LEU A C   1 
ATOM   3205 O O   . LEU B 2 137 ? -7.34   -28.689 18.166  1   29.65  ? 133 LEU A O   1 
ATOM   3206 C CB  . LEU B 2 137 ? -7.961  -28.742 15.32   1   24.26  ? 133 LEU A CB  1 
ATOM   3207 C CG  . LEU B 2 137 ? -7.796  -28.412 13.83   1   24.08  ? 133 LEU A CG  1 
ATOM   3208 C CD1 . LEU B 2 137 ? -7.671  -29.66  12.958  1   21.56  ? 133 LEU A CD1 1 
ATOM   3209 C CD2 . LEU B 2 137 ? -8.959  -27.542 13.354  1   23.52  ? 133 LEU A CD2 1 
ATOM   3210 N N   . LEU B 2 138 ? -9.228  -27.425 18.373  1   27.17  ? 134 LEU A N   1 
ATOM   3211 C CA  . LEU B 2 138 ? -9.379  -27.598 19.813  1   28.62  ? 134 LEU A CA  1 
ATOM   3212 C C   . LEU B 2 138 ? -10.315 -28.749 20.187  1   28.68  ? 134 LEU A C   1 
ATOM   3213 O O   . LEU B 2 138 ? -11.467 -28.791 19.764  1   32.05  ? 134 LEU A O   1 
ATOM   3214 C CB  . LEU B 2 138 ? -9.91   -26.267 20.326  1   28.54  ? 134 LEU A CB  1 
ATOM   3215 C CG  . LEU B 2 138 ? -8.923  -25.113 20.163  1   30.26  ? 134 LEU A CG  1 
ATOM   3216 C CD1 . LEU B 2 138 ? -9.286  -23.924 21.037  1   31.13  ? 134 LEU A CD1 1 
ATOM   3217 C CD2 . LEU B 2 138 ? -7.508  -25.576 20.467  1   29.16  ? 134 LEU A CD2 1 
ATOM   3218 N N   . ILE B 2 139 ? -9.837  -29.656 21.03   1   27.45  ? 135 ILE A N   1 
ATOM   3219 C CA  . ILE B 2 139 ? -10.651 -30.773 21.483  1   28.89  ? 135 ILE A CA  1 
ATOM   3220 C C   . ILE B 2 139 ? -11.151 -30.495 22.905  1   30.51  ? 135 ILE A C   1 
ATOM   3221 O O   . ILE B 2 139 ? -10.532 -29.75  23.638  1   33.14  ? 135 ILE A O   1 
ATOM   3222 C CB  . ILE B 2 139 ? -9.882  -32.118 21.37   1   28.26  ? 135 ILE A CB  1 
ATOM   3223 C CG1 . ILE B 2 139 ? -8.654  -32.221 22.273  1   26.61  ? 135 ILE A CG1 1 
ATOM   3224 C CG2 . ILE B 2 139 ? -9.508  -32.422 19.923  1   27.08  ? 135 ILE A CG2 1 
ATOM   3225 C CD1 . ILE B 2 139 ? -8.033  -33.597 22.249  1   26.08  ? 135 ILE A CD1 1 
ATOM   3226 N N   . ASN B 2 140 ? -12.247 -31.132 23.315  1   31.35  ? 136 ASN A N   1 
ATOM   3227 C CA  . ASN B 2 140 ? -12.723 -31.075 24.693  1   32.39  ? 136 ASN A CA  1 
ATOM   3228 C C   . ASN B 2 140 ? -12.902 -32.496 25.249  1   33.93  ? 136 ASN A C   1 
ATOM   3229 O O   . ASN B 2 140 ? -12.576 -33.492 24.589  1   36.23  ? 136 ASN A O   1 
ATOM   3230 C CB  . ASN B 2 140 ? -13.967 -30.197 24.817  1   29.85  ? 136 ASN A CB  1 
ATOM   3231 C CG  . ASN B 2 140 ? -15.194 -30.875 24.26   1   29.51  ? 136 ASN A CG  1 
ATOM   3232 O OD1 . ASN B 2 140 ? -15.257 -32.107 24.168  1   31.07  ? 136 ASN A OD1 1 
ATOM   3233 N ND2 . ASN B 2 140 ? -16.195 -30.102 23.874  1   28.78  ? 136 ASN A ND2 1 
ATOM   3234 N N   . THR B 2 141 ? -13.453 -32.575 26.465  1   33.3   ? 137 THR A N   1 
ATOM   3235 C CA  . THR B 2 141 ? -13.452 -33.819 27.216  1   34.17  ? 137 THR A CA  1 
ATOM   3236 C C   . THR B 2 141 ? -14.62  -34.683 26.773  1   33.69  ? 137 THR A C   1 
ATOM   3237 O O   . THR B 2 141 ? -14.664 -35.845 27.13   1   35.67  ? 137 THR A O   1 
ATOM   3238 C CB  . THR B 2 141 ? -13.496 -33.597 28.735  1   35.61  ? 137 THR A CB  1 
ATOM   3239 O OG1 . THR B 2 141 ? -14.502 -32.63  29.016  1   36.99  ? 137 THR A OG1 1 
ATOM   3240 C CG2 . THR B 2 141 ? -12.191 -33.081 29.315  1   34.53  ? 137 THR A CG2 1 
ATOM   3241 N N   . GLU B 2 142 ? -15.568 -34.105 26.029  1   33.67  ? 138 GLU A N   1 
ATOM   3242 C CA  . GLU B 2 142 ? -16.769 -34.811 25.596  1   35.09  ? 138 GLU A CA  1 
ATOM   3243 C C   . GLU B 2 142 ? -16.602 -35.353 24.17   1   33.35  ? 138 GLU A C   1 
ATOM   3244 O O   . GLU B 2 142 ? -17.48  -35.988 23.608  1   32.35  ? 138 GLU A O   1 
ATOM   3245 C CB  . GLU B 2 142 ? -17.949 -33.852 25.768  1   36.67  ? 138 GLU A CB  1 
ATOM   3246 C CG  . GLU B 2 142 ? -18.242 -33.526 27.226  1   42.38  ? 138 GLU A CG  1 
ATOM   3247 C CD  . GLU B 2 142 ? -18.707 -34.696 28.088  1   52.64  ? 138 GLU A CD  1 
ATOM   3248 O OE1 . GLU B 2 142 ? -19.931 -34.682 28.331  1   56.6   ? 138 GLU A OE1 1 
ATOM   3249 O OE2 . GLU B 2 142 ? -17.919 -35.584 28.544  1   56.32  ? 138 GLU A OE2 1 
ATOM   3250 N N   . GLY B 2 143 ? -15.442 -35.112 23.574  1   35.04  ? 139 GLY A N   1 
ATOM   3251 C CA  . GLY B 2 143 ? -15.105 -35.715 22.296  1   35.21  ? 139 GLY A CA  1 
ATOM   3252 C C   . GLY B 2 143 ? -15.461 -34.816 21.12   1   31.4   ? 139 GLY A C   1 
ATOM   3253 O O   . GLY B 2 143 ? -15.493 -35.314 19.99   1   30.28  ? 139 GLY A O   1 
ATOM   3254 N N   . ALA B 2 144 ? -15.748 -33.537 21.427  1   28.61  ? 140 ALA A N   1 
ATOM   3255 C CA  . ALA B 2 144 ? -15.886 -32.493 20.422  1   27.16  ? 140 ALA A CA  1 
ATOM   3256 C C   . ALA B 2 144 ? -14.506 -32.062 19.926  1   26.32  ? 140 ALA A C   1 
ATOM   3257 O O   . ALA B 2 144 ? -13.539 -32.098 20.679  1   31.18  ? 140 ALA A O   1 
ATOM   3258 C CB  . ALA B 2 144 ? -16.641 -31.323 20.997  1   25.55  ? 140 ALA A CB  1 
ATOM   3259 N N   . ILE B 2 145 ? -14.398 -31.729 18.642  1   23.46  ? 141 ILE A N   1 
ATOM   3260 C CA  . ILE B 2 145 ? -13.241 -31.017 18.12   1   22.99  ? 141 ILE A CA  1 
ATOM   3261 C C   . ILE B 2 145 ? -13.774 -29.797 17.377  1   23.11  ? 141 ILE A C   1 
ATOM   3262 O O   . ILE B 2 145 ? -14.873 -29.851 16.805  1   23.98  ? 141 ILE A O   1 
ATOM   3263 C CB  . ILE B 2 145 ? -12.379 -31.914 17.206  1   22.65  ? 141 ILE A CB  1 
ATOM   3264 C CG1 . ILE B 2 145 ? -11.033 -31.284 16.895  1   23.03  ? 141 ILE A CG1 1 
ATOM   3265 C CG2 . ILE B 2 145 ? -13.109 -32.295 15.921  1   22.61  ? 141 ILE A CG2 1 
ATOM   3266 C CD1 . ILE B 2 145 ? -10.06  -32.203 16.174  1   23.32  ? 141 ILE A CD1 1 
ATOM   3267 N N   . LYS B 2 146 ? -13.026 -28.685 17.417  1   22.81  ? 142 LYS A N   1 
ATOM   3268 C CA  . LYS B 2 146 ? -13.561 -27.425 16.892  1   22.91  ? 142 LYS A CA  1 
ATOM   3269 C C   . LYS B 2 146 ? -12.452 -26.636 16.216  1   22.52  ? 142 LYS A C   1 
ATOM   3270 O O   . LYS B 2 146 ? -11.342 -26.582 16.752  1   23.61  ? 142 LYS A O   1 
ATOM   3271 C CB  . LYS B 2 146 ? -14.244 -26.551 17.951  1   21.59  ? 142 LYS A CB  1 
ATOM   3272 C CG  . LYS B 2 146 ? -15.25  -27.323 18.769  1   21.31  ? 142 LYS A CG  1 
ATOM   3273 C CD  . LYS B 2 146 ? -16.112 -26.429 19.635  1   22.13  ? 142 LYS A CD  1 
ATOM   3274 C CE  . LYS B 2 146 ? -16.799 -27.206 20.708  1   22.12  ? 142 LYS A CE  1 
ATOM   3275 N NZ  . LYS B 2 146 ? -18.103 -26.617 21.003  1   20.7   ? 142 LYS A NZ  1 
ATOM   3276 N N   . LEU B 2 147 ? -12.786 -26.077 15.041  1   21.58  ? 143 LEU A N   1 
ATOM   3277 C CA  . LEU B 2 147 ? -11.949 -25.154 14.289  1   21.57  ? 143 LEU A CA  1 
ATOM   3278 C C   . LEU B 2 147 ? -11.711 -23.92  15.148  1   22.78  ? 143 LEU A C   1 
ATOM   3279 O O   . LEU B 2 147 ? -12.67  -23.352 15.652  1   23.86  ? 143 LEU A O   1 
ATOM   3280 C CB  . LEU B 2 147 ? -12.671 -24.704 13.013  1   21.02  ? 143 LEU A CB  1 
ATOM   3281 C CG  . LEU B 2 147 ? -13.163 -25.771 12.024  1   19.63  ? 143 LEU A CG  1 
ATOM   3282 C CD1 . LEU B 2 147 ? -13.15  -25.196 10.624  1   18.38  ? 143 LEU A CD1 1 
ATOM   3283 C CD2 . LEU B 2 147 ? -12.373 -27.032 12.068  1   18.95  ? 143 LEU A CD2 1 
ATOM   3284 N N   . ALA B 2 148 ? -10.447 -23.49  15.265  1   24.18  ? 144 ALA A N   1 
ATOM   3285 C CA  . ALA B 2 148 ? -10.09  -22.311 16.042  1   25.63  ? 144 ALA A CA  1 
ATOM   3286 C C   . ALA B 2 148 ? -9.122  -21.428 15.247  1   30.89  ? 144 ALA A C   1 
ATOM   3287 O O   . ALA B 2 148 ? -8.746  -21.743 14.107  1   32.32  ? 144 ALA A O   1 
ATOM   3288 C CB  . ALA B 2 148 ? -9.507  -22.739 17.352  1   22.3   ? 144 ALA A CB  1 
ATOM   3289 N N   . ASP B 2 149 ? -8.731  -20.312 15.872  1   33.11  ? 145 ASP A N   1 
ATOM   3290 C CA  . ASP B 2 149 ? -7.824  -19.321 15.317  1   34.54  ? 145 ASP A CA  1 
ATOM   3291 C C   . ASP B 2 149 ? -8.28   -18.86  13.933  1   34.29  ? 145 ASP A C   1 
ATOM   3292 O O   . ASP B 2 149 ? -7.718  -19.306 12.939  1   35.12  ? 145 ASP A O   1 
ATOM   3293 C CB  . ASP B 2 149 ? -6.391  -19.816 15.335  1   36.61  ? 145 ASP A CB  1 
ATOM   3294 C CG  . ASP B 2 149 ? -5.344  -18.71  15.212  1   46.87  ? 145 ASP A CG  1 
ATOM   3295 O OD1 . ASP B 2 149 ? -5.713  -17.592 14.778  1   45.38  ? 145 ASP A OD1 1 
ATOM   3296 O OD2 . ASP B 2 149 ? -4.171  -18.948 15.589  1   52.26  ? 145 ASP A OD2 1 
ATOM   3297 N N   . PHE B 2 150 ? -9.275  -17.958 13.87   1   32.1   ? 146 PHE A N   1 
ATOM   3298 C CA  . PHE B 2 150 ? -9.754  -17.413 12.601  1   29.96  ? 146 PHE A CA  1 
ATOM   3299 C C   . PHE B 2 150 ? -8.98   -16.142 12.234  1   33.63  ? 146 PHE A C   1 
ATOM   3300 O O   . PHE B 2 150 ? -9.501  -15.23  11.594  1   35.26  ? 146 PHE A O   1 
ATOM   3301 C CB  . PHE B 2 150 ? -11.273 -17.218 12.66   1   25.66  ? 146 PHE A CB  1 
ATOM   3302 C CG  . PHE B 2 150 ? -12.059 -18.473 12.321  1   23.95  ? 146 PHE A CG  1 
ATOM   3303 C CD1 . PHE B 2 150 ? -12.147 -19.53  13.225  1   23.9   ? 146 PHE A CD1 1 
ATOM   3304 C CD2 . PHE B 2 150 ? -12.668 -18.619 11.074  1   21.91  ? 146 PHE A CD2 1 
ATOM   3305 C CE1 . PHE B 2 150 ? -12.862 -20.676 12.901  1   22.22  ? 146 PHE A CE1 1 
ATOM   3306 C CE2 . PHE B 2 150 ? -13.365 -19.768 10.751  1   19.85  ? 146 PHE A CE2 1 
ATOM   3307 C CZ  . PHE B 2 150 ? -13.454 -20.794 11.659  1   20.71  ? 146 PHE A CZ  1 
ATOM   3308 N N   . GLY B 2 151 ? -7.704  -16.09  12.616  1   34.48  ? 147 GLY A N   1 
ATOM   3309 C CA  . GLY B 2 151 ? -6.942  -14.866 12.471  1   35.87  ? 147 GLY A CA  1 
ATOM   3310 C C   . GLY B 2 151 ? -6.597  -14.619 11.014  1   35.81  ? 147 GLY A C   1 
ATOM   3311 O O   . GLY B 2 151 ? -6.519  -13.477 10.589  1   40.24  ? 147 GLY A O   1 
ATOM   3312 N N   . LEU B 2 152 ? -6.451  -15.706 10.26   1   35.24  ? 148 LEU A N   1 
ATOM   3313 C CA  . LEU B 2 152 ? -5.964  -15.644 8.892   1   36.02  ? 148 LEU A CA  1 
ATOM   3314 C C   . LEU B 2 152 ? -7.089  -15.939 7.892   1   34.66  ? 148 LEU A C   1 
ATOM   3315 O O   . LEU B 2 152 ? -6.831  -16.114 6.7     1   34.58  ? 148 LEU A O   1 
ATOM   3316 C CB  . LEU B 2 152 ? -4.854  -16.683 8.78    1   36.23  ? 148 LEU A CB  1 
ATOM   3317 C CG  . LEU B 2 152 ? -4.244  -16.838 7.393   1   36.68  ? 148 LEU A CG  1 
ATOM   3318 C CD1 . LEU B 2 152 ? -3.611  -15.48  7.103   1   36.12  ? 148 LEU A CD1 1 
ATOM   3319 C CD2 . LEU B 2 152 ? -3.244  -18.006 7.391   1   36.23  ? 148 LEU A CD2 1 
ATOM   3320 N N   . ALA B 2 153 ? -8.335  -15.984 8.387   1   33.87  ? 149 ALA A N   1 
ATOM   3321 C CA  . ALA B 2 153 ? -9.509  -16.329 7.597   1   30.83  ? 149 ALA A CA  1 
ATOM   3322 C C   . ALA B 2 153 ? -9.925  -15.12  6.792   1   30.4   ? 149 ALA A C   1 
ATOM   3323 O O   . ALA B 2 153 ? -9.457  -14.026 7.07    1   30.29  ? 149 ALA A O   1 
ATOM   3324 C CB  . ALA B 2 153 ? -10.638 -16.708 8.502   1   29.08  ? 149 ALA A CB  1 
ATOM   3325 N N   . ARG B 2 154 ? -10.731 -15.413 5.743   1   29.32  ? 150 ARG A N   1 
ATOM   3326 C CA  . ARG B 2 154 ? -11.163 -14.339 4.824   1   30.24  ? 150 ARG A CA  1 
ATOM   3327 C C   . ARG B 2 154 ? -12.554 -14.619 4.267   1   31.31  ? 150 ARG A C   1 
ATOM   3328 O O   . ARG B 2 154 ? -12.863 -15.78  3.981   1   33.5   ? 150 ARG A O   1 
ATOM   3329 C CB  . ARG B 2 154 ? -10.204 -14.23  3.638   1   29.63  ? 150 ARG A CB  1 
ATOM   3330 C CG  . ARG B 2 154 ? -10.538 -13.362 2.437   1   29.8   ? 150 ARG A CG  1 
ATOM   3331 C CD  . ARG B 2 154 ? -9.917  -12.012 2.677   1   32.34  ? 150 ARG A CD  1 
ATOM   3332 N NE  . ARG B 2 154 ? -9.012  -11.603 1.602   1   33.79  ? 150 ARG A NE  1 
ATOM   3333 C CZ  . ARG B 2 154 ? -9.102  -10.425 1.025   1   36.4   ? 150 ARG A CZ  1 
ATOM   3334 N NH1 . ARG B 2 154 ? -10.289 -9.884  0.845   1   38.07  ? 150 ARG A NH1 1 
ATOM   3335 N NH2 . ARG B 2 154 ? -8.015  -9.79   0.638   1   37.01  ? 150 ARG A NH2 1 
ATOM   3336 N N   . ALA B 2 155 ? -13.352 -13.542 4.123   1   30.21  ? 151 ALA A N   1 
ATOM   3337 C CA  . ALA B 2 155 ? -14.654 -13.66  3.488   1   28.98  ? 151 ALA A CA  1 
ATOM   3338 C C   . ALA B 2 155 ? -14.487 -13.581 1.972   1   29.8   ? 151 ALA A C   1 
ATOM   3339 O O   . ALA B 2 155 ? -13.988 -12.589 1.448   1   30.45  ? 151 ALA A O   1 
ATOM   3340 C CB  . ALA B 2 155 ? -15.548 -12.542 3.986   1   29.39  ? 151 ALA A CB  1 
ATOM   3341 N N   . PHE B 2 156 ? -14.912 -14.631 1.264   1   29.8   ? 152 PHE A N   1 
ATOM   3342 C CA  . PHE B 2 156 ? -14.769 -14.646 -0.183  1   30.23  ? 152 PHE A CA  1 
ATOM   3343 C C   . PHE B 2 156 ? -16.079 -14.25  -0.859  1   34.25  ? 152 PHE A C   1 
ATOM   3344 O O   . PHE B 2 156 ? -17.13  -14.129 -0.206  1   39.43  ? 152 PHE A O   1 
ATOM   3345 C CB  . PHE B 2 156 ? -14.246 -15.985 -0.694  1   28.12  ? 152 PHE A CB  1 
ATOM   3346 C CG  . PHE B 2 156 ? -15.101 -17.22  -0.46   1   27.91  ? 152 PHE A CG  1 
ATOM   3347 C CD1 . PHE B 2 156 ? -14.989 -17.948 0.724   1   26.51  ? 152 PHE A CD1 1 
ATOM   3348 C CD2 . PHE B 2 156 ? -15.981 -17.682 -1.438  1   28.19  ? 152 PHE A CD2 1 
ATOM   3349 C CE1 . PHE B 2 156 ? -15.747 -19.093 0.928   1   24.73  ? 152 PHE A CE1 1 
ATOM   3350 C CE2 . PHE B 2 156 ? -16.707 -18.856 -1.243  1   26.54  ? 152 PHE A CE2 1 
ATOM   3351 C CZ  . PHE B 2 156 ? -16.614 -19.539 -0.053  1   25.13  ? 152 PHE A CZ  1 
ATOM   3352 N N   . GLY B 2 157 ? -15.962 -13.954 -2.162  1   32.74  ? 153 GLY A N   1 
ATOM   3353 C CA  . GLY B 2 157 ? -17.092 -13.719 -3.04   1   31.94  ? 153 GLY A CA  1 
ATOM   3354 C C   . GLY B 2 157 ? -17.14  -14.851 -4.06   1   31.63  ? 153 GLY A C   1 
ATOM   3355 O O   . GLY B 2 157 ? -16.227 -15.662 -4.099  1   29.31  ? 153 GLY A O   1 
ATOM   3356 N N   . VAL B 2 158 ? -18.189 -14.885 -4.899  1   32.72  ? 154 VAL A N   1 
ATOM   3357 C CA  . VAL B 2 158 ? -18.324 -15.963 -5.859  1   30.86  ? 154 VAL A CA  1 
ATOM   3358 C C   . VAL B 2 158 ? -18.385 -15.359 -7.251  1   31.57  ? 154 VAL A C   1 
ATOM   3359 O O   . VAL B 2 158 ? -19.307 -14.624 -7.544  1   34.44  ? 154 VAL A O   1 
ATOM   3360 C CB  . VAL B 2 158 ? -19.571 -16.818 -5.564  1   31.34  ? 154 VAL A CB  1 
ATOM   3361 C CG1 . VAL B 2 158 ? -19.762 -17.878 -6.643  1   32.08  ? 154 VAL A CG1 1 
ATOM   3362 C CG2 . VAL B 2 158 ? -19.531 -17.461 -4.17   1   28.72  ? 154 VAL A CG2 1 
ATOM   3363 N N   . PRO B 2 159 ? -17.423 -15.637 -8.158  1   31.08  ? 155 PRO A N   1 
ATOM   3364 C CA  . PRO B 2 159 ? -16.205 -16.388 -7.835  1   29.9   ? 155 PRO A CA  1 
ATOM   3365 C C   . PRO B 2 159 ? -15.141 -15.676 -7.021  1   30.91  ? 155 PRO A C   1 
ATOM   3366 O O   . PRO B 2 159 ? -15.137 -14.451 -6.875  1   32.77  ? 155 PRO A O   1 
ATOM   3367 C CB  . PRO B 2 159 ? -15.623 -16.716 -9.198  1   28.87  ? 155 PRO A CB  1 
ATOM   3368 C CG  . PRO B 2 159 ? -16.118 -15.616 -10.073 1   30.56  ? 155 PRO A CG  1 
ATOM   3369 C CD  . PRO B 2 159 ? -17.529 -15.358 -9.597  1   31.78  ? 155 PRO A CD  1 
ATOM   3370 N N   . VAL B 2 160 ? -14.181 -16.467 -6.55   1   29.66  ? 156 VAL A N   1 
ATOM   3371 C CA  . VAL B 2 160 ? -13.147 -15.874 -5.73   1   30     ? 156 VAL A CA  1 
ATOM   3372 C C   . VAL B 2 160 ? -12.37  -14.876 -6.581  1   34.19  ? 156 VAL A C   1 
ATOM   3373 O O   . VAL B 2 160 ? -12.372 -14.918 -7.815  1   39.05  ? 156 VAL A O   1 
ATOM   3374 C CB  . VAL B 2 160 ? -12.231 -16.95  -5.133  1   26.77  ? 156 VAL A CB  1 
ATOM   3375 C CG1 . VAL B 2 160 ? -13.001 -17.864 -4.188  1   23.76  ? 156 VAL A CG1 1 
ATOM   3376 C CG2 . VAL B 2 160 ? -11.517 -17.721 -6.235  1   25.62  ? 156 VAL A CG2 1 
ATOM   3377 N N   . ARG B 2 161 ? -11.734 -13.943 -5.889  1   34.95  ? 157 ARG A N   1 
ATOM   3378 C CA  . ARG B 2 161 ? -10.852 -12.968 -6.49   1   36.9   ? 157 ARG A CA  1 
ATOM   3379 C C   . ARG B 2 161 ? -9.465  -13.314 -5.95   1   37.51  ? 157 ARG A C   1 
ATOM   3380 O O   . ARG B 2 161 ? -9.348  -14.191 -5.081  1   34.92  ? 157 ARG A O   1 
ATOM   3381 C CB  . ARG B 2 161 ? -11.48  -11.629 -6.069  1   38.31  ? 157 ARG A CB  1 
ATOM   3382 C CG  . ARG B 2 161 ? -10.529 -10.521 -5.649  1   41.43  ? 157 ARG A CG  1 
ATOM   3383 C CD  . ARG B 2 161 ? -11.164 -9.159  -5.77   1   46.67  ? 157 ARG A CD  1 
ATOM   3384 N NE  . ARG B 2 161 ? -11.871 -8.736  -4.556  1   51.52  ? 157 ARG A NE  1 
ATOM   3385 C CZ  . ARG B 2 161 ? -11.323 -8.562  -3.333  1   51.89  ? 157 ARG A CZ  1 
ATOM   3386 N NH1 . ARG B 2 161 ? -12.087 -8.104  -2.349  1   49.85  ? 157 ARG A NH1 1 
ATOM   3387 N NH2 . ARG B 2 161 ? -10.036 -8.82   -3.101  1   47.3   ? 157 ARG A NH2 1 
ATOM   3388 N N   . THR B 2 162 ? -8.417  -12.657 -6.474  1   39.03  ? 158 THR A N   1 
ATOM   3389 C CA  . THR B 2 162 ? -7.083  -12.85  -5.917  1   38.25  ? 158 THR A CA  1 
ATOM   3390 C C   . THR B 2 162 ? -7.082  -12.397 -4.462  1   37.08  ? 158 THR A C   1 
ATOM   3391 O O   . THR B 2 162 ? -7.387  -11.252 -4.166  1   37.39  ? 158 THR A O   1 
ATOM   3392 C CB  . THR B 2 162 ? -5.998  -12.14  -6.734  1   41.12  ? 158 THR A CB  1 
ATOM   3393 O OG1 . THR B 2 162 ? -6.06   -12.607 -8.078  1   44.26  ? 158 THR A OG1 1 
ATOM   3394 C CG2 . THR B 2 162 ? -4.587  -12.411 -6.238  1   38.87  ? 158 THR A CG2 1 
ATOM   3395 N N   . TYR B 2 163 ? -6.704  -13.311 -3.568  1   37.53  ? 159 TYR A N   1 
ATOM   3396 C CA  . TYR B 2 163 ? -6.464  -12.96  -2.179  1   39.38  ? 159 TYR A CA  1 
ATOM   3397 C C   . TYR B 2 163 ? -4.978  -13.095 -1.85   1   38.68  ? 159 TYR A C   1 
ATOM   3398 O O   . TYR B 2 163 ? -4.15   -13.38  -2.73   1   40.04  ? 159 TYR A O   1 
ATOM   3399 C CB  . TYR B 2 163 ? -7.307  -13.878 -1.29   1   42.53  ? 159 TYR A CB  1 
ATOM   3400 C CG  . TYR B 2 163 ? -8.78   -13.909 -1.67   1   43.92  ? 159 TYR A CG  1 
ATOM   3401 C CD1 . TYR B 2 163 ? -9.519  -12.739 -1.744  1   43.08  ? 159 TYR A CD1 1 
ATOM   3402 C CD2 . TYR B 2 163 ? -9.41   -15.106 -1.989  1   41.53  ? 159 TYR A CD2 1 
ATOM   3403 C CE1 . TYR B 2 163 ? -10.849 -12.762 -2.114  1   44.55  ? 159 TYR A CE1 1 
ATOM   3404 C CE2 . TYR B 2 163 ? -10.739 -15.135 -2.364  1   39.1   ? 159 TYR A CE2 1 
ATOM   3405 C CZ  . TYR B 2 163 ? -11.463 -13.96  -2.42   1   40.82  ? 159 TYR A CZ  1 
ATOM   3406 O OH  . TYR B 2 163 ? -12.779 -13.939 -2.792  1   42.2   ? 159 TYR A OH  1 
HETATM 3407 N N   . TPO B 2 164 ? -4.675  -12.876 -0.564  1   35.02  ? 160 TPO A N   1 
HETATM 3408 C CA  . TPO B 2 164 ? -3.345  -12.981 0.009   1   36.03  ? 160 TPO A CA  1 
HETATM 3409 C CB  . TPO B 2 164 ? -3.44   -12.813 1.52    1   35.04  ? 160 TPO A CB  1 
HETATM 3410 C CG2 . TPO B 2 164 ? -2.107  -12.843 2.221   1   35.01  ? 160 TPO A CG2 1 
HETATM 3411 O OG1 . TPO B 2 164 ? -4.045  -11.506 1.724   1   37.95  ? 160 TPO A OG1 1 
HETATM 3412 P P   . TPO B 2 164 ? -5.393  -11.552 2.593   1   39.2   ? 160 TPO A P   1 
HETATM 3413 O O1P . TPO B 2 164 ? -6.426  -12.342 1.799   1   36.83  ? 160 TPO A O1P 1 
HETATM 3414 O O2P . TPO B 2 164 ? -5.765  -10.075 2.856   1   37.48  ? 160 TPO A O2P 1 
HETATM 3415 O O3P . TPO B 2 164 ? -4.987  -12.327 3.822   1   36.17  ? 160 TPO A O3P 1 
HETATM 3416 C C   . TPO B 2 164 ? -2.685  -14.326 -0.299  1   37.71  ? 160 TPO A C   1 
HETATM 3417 O O   . TPO B 2 164 ? -3.324  -15.375 -0.257  1   35.72  ? 160 TPO A O   1 
ATOM   3418 N N   . HIS B 2 165 ? -1.377  -14.259 -0.57   1   40.64  ? 161 HIS A N   1 
ATOM   3419 C CA  . HIS B 2 165 ? -0.582  -15.369 -1.05   1   42.94  ? 161 HIS A CA  1 
ATOM   3420 C C   . HIS B 2 165 ? 0.11    -16.113 0.098   1   46.29  ? 161 HIS A C   1 
ATOM   3421 O O   . HIS B 2 165 ? 0.217   -17.341 0.1     1   43.49  ? 161 HIS A O   1 
ATOM   3422 C CB  . HIS B 2 165 ? 0.498   -14.831 -1.986  1   49.07  ? 161 HIS A CB  1 
ATOM   3423 C CG  . HIS B 2 165 ? 1.346   -15.969 -2.424  1   64.23  ? 161 HIS A CG  1 
ATOM   3424 N ND1 . HIS B 2 165 ? 0.762   -17.11  -2.946  1   63.21  ? 161 HIS A ND1 1 
ATOM   3425 C CD2 . HIS B 2 165 ? 2.673   -16.198 -2.388  1   70.99  ? 161 HIS A CD2 1 
ATOM   3426 C CE1 . HIS B 2 165 ? 1.71    -17.981 -3.247  1   65.66  ? 161 HIS A CE1 1 
ATOM   3427 N NE2 . HIS B 2 165 ? 2.877   -17.453 -2.918  1   70.25  ? 161 HIS A NE2 1 
ATOM   3428 N N   . GLU B 2 166 ? 0.656   -15.353 1.05    1   55.92  ? 162 GLU A N   1 
ATOM   3429 C CA  . GLU B 2 166 ? 1.302   -15.926 2.223   1   62.47  ? 162 GLU A CA  1 
ATOM   3430 C C   . GLU B 2 166 ? 0.203   -16.394 3.181   1   66.05  ? 162 GLU A C   1 
ATOM   3431 O O   . GLU B 2 166 ? -0.157  -15.664 4.111   1   73.37  ? 162 GLU A O   1 
ATOM   3432 C CB  . GLU B 2 166 ? 2.386   -15.013 2.822   1   66.96  ? 162 GLU A CB  1 
ATOM   3433 C CG  . GLU B 2 166 ? 2.095   -13.516 2.708   1   80.68  ? 162 GLU A CG  1 
ATOM   3434 C CD  . GLU B 2 166 ? 2.648   -12.712 1.533   1   89.54  ? 162 GLU A CD  1 
ATOM   3435 O OE1 . GLU B 2 166 ? 2.478   -13.081 0.335   1   85.53  ? 162 GLU A OE1 1 
ATOM   3436 O OE2 . GLU B 2 166 ? 3.265   -11.674 1.856   1   96.03  ? 162 GLU A OE2 1 
ATOM   3437 N N   . VAL B 2 167 ? -0.346  -17.595 2.907   1   58.14  ? 163 VAL A N   1 
ATOM   3438 C CA  . VAL B 2 167 ? -1.456  -18.157 3.671   1   47.16  ? 163 VAL A CA  1 
ATOM   3439 C C   . VAL B 2 167 ? -1.194  -19.638 3.912   1   40.58  ? 163 VAL A C   1 
ATOM   3440 O O   . VAL B 2 167 ? -0.665  -20.3   3.031   1   39.14  ? 163 VAL A O   1 
ATOM   3441 C CB  . VAL B 2 167 ? -2.818  -17.979 2.968   1   44.47  ? 163 VAL A CB  1 
ATOM   3442 C CG1 . VAL B 2 167 ? -3.296  -16.535 3.009   1   39.45  ? 163 VAL A CG1 1 
ATOM   3443 C CG2 . VAL B 2 167 ? -2.818  -18.555 1.553   1   38.46  ? 163 VAL A CG2 1 
ATOM   3444 N N   . VAL B 2 168 ? -1.621  -20.135 5.085   1   36.99  ? 164 VAL A N   1 
ATOM   3445 C CA  . VAL B 2 168 ? -1.542  -21.539 5.484   1   31.46  ? 164 VAL A CA  1 
ATOM   3446 C C   . VAL B 2 168 ? -0.118  -21.861 5.908   1   30.32  ? 164 VAL A C   1 
ATOM   3447 O O   . VAL B 2 168 ? 0.801   -21.651 5.131   1   33.25  ? 164 VAL A O   1 
ATOM   3448 C CB  . VAL B 2 168 ? -2.017  -22.577 4.446   1   28.3   ? 164 VAL A CB  1 
ATOM   3449 C CG1 . VAL B 2 168 ? -2.142  -23.956 5.081   1   27.99  ? 164 VAL A CG1 1 
ATOM   3450 C CG2 . VAL B 2 168 ? -3.342  -22.186 3.806   1   26.19  ? 164 VAL A CG2 1 
ATOM   3451 N N   . THR B 2 169 ? 0.042   -22.408 7.121   1   29.31  ? 165 THR A N   1 
ATOM   3452 C CA  . THR B 2 169 ? 1.303   -22.989 7.575   1   26.94  ? 165 THR A CA  1 
ATOM   3453 C C   . THR B 2 169 ? 1.806   -23.98  6.514   1   26.62  ? 165 THR A C   1 
ATOM   3454 O O   . THR B 2 169 ? 1.043   -24.768 5.944   1   24.87  ? 165 THR A O   1 
ATOM   3455 C CB  . THR B 2 169 ? 1.072   -23.66  8.931   1   25.2   ? 165 THR A CB  1 
ATOM   3456 O OG1 . THR B 2 169 ? 0.491   -22.664 9.761   1   26.39  ? 165 THR A OG1 1 
ATOM   3457 C CG2 . THR B 2 169 ? 2.333   -24.215 9.563   1   24.84  ? 165 THR A CG2 1 
ATOM   3458 N N   . LEU B 2 170 ? 3.117   -23.951 6.282   1   27.03  ? 166 LEU A N   1 
ATOM   3459 C CA  . LEU B 2 170 ? 3.727   -24.538 5.106   1   26.49  ? 166 LEU A CA  1 
ATOM   3460 C C   . LEU B 2 170 ? 3.265   -25.978 4.945   1   26.7   ? 166 LEU A C   1 
ATOM   3461 O O   . LEU B 2 170 ? 2.72    -26.342 3.902   1   26.57  ? 166 LEU A O   1 
ATOM   3462 C CB  . LEU B 2 170 ? 5.248   -24.454 5.241   1   26.42  ? 166 LEU A CB  1 
ATOM   3463 C CG  . LEU B 2 170 ? 6.052   -24.994 4.055   1   25.35  ? 166 LEU A CG  1 
ATOM   3464 C CD1 . LEU B 2 170 ? 5.541   -24.431 2.73    1   23.67  ? 166 LEU A CD1 1 
ATOM   3465 C CD2 . LEU B 2 170 ? 7.521   -24.726 4.272   1   25.36  ? 166 LEU A CD2 1 
ATOM   3466 N N   . TRP B 2 171 ? 3.487   -26.774 5.992   1   25.85  ? 167 TRP A N   1 
ATOM   3467 C CA  . TRP B 2 171 ? 3.251   -28.2   5.914   1   26.25  ? 167 TRP A CA  1 
ATOM   3468 C C   . TRP B 2 171 ? 1.837   -28.531 5.44    1   28.89  ? 167 TRP A C   1 
ATOM   3469 O O   . TRP B 2 171 ? 1.636   -29.635 4.938   1   33.73  ? 167 TRP A O   1 
ATOM   3470 C CB  . TRP B 2 171 ? 3.503   -28.839 7.275   1   26.74  ? 167 TRP A CB  1 
ATOM   3471 C CG  . TRP B 2 171 ? 4.939   -28.808 7.696   1   30.51  ? 167 TRP A CG  1 
ATOM   3472 C CD1 . TRP B 2 171 ? 6.024   -28.434 6.966   1   34.07  ? 167 TRP A CD1 1 
ATOM   3473 C CD2 . TRP B 2 171 ? 5.446   -29.204 8.979   1   32.45  ? 167 TRP A CD2 1 
ATOM   3474 N NE1 . TRP B 2 171 ? 7.176   -28.57  7.701   1   35.47  ? 167 TRP A NE1 1 
ATOM   3475 C CE2 . TRP B 2 171 ? 6.848   -29.041 8.935   1   34.99  ? 167 TRP A CE2 1 
ATOM   3476 C CE3 . TRP B 2 171 ? 4.839   -29.678 10.143  1   33.38  ? 167 TRP A CE3 1 
ATOM   3477 C CZ2 . TRP B 2 171 ? 7.663   -29.333 10.012  1   39.32  ? 167 TRP A CZ2 1 
ATOM   3478 C CZ3 . TRP B 2 171 ? 5.638   -29.985 11.211  1   35.61  ? 167 TRP A CZ3 1 
ATOM   3479 C CH2 . TRP B 2 171 ? 7.021   -29.795 11.142  1   42.08  ? 167 TRP A CH2 1 
ATOM   3480 N N   . TYR B 2 172 ? 0.876   -27.591 5.584   1   28.61  ? 168 TYR A N   1 
ATOM   3481 C CA  . TYR B 2 172 ? -0.546  -27.832 5.34    1   26.99  ? 168 TYR A CA  1 
ATOM   3482 C C   . TYR B 2 172 ? -1.014  -27.087 4.087   1   30.75  ? 168 TYR A C   1 
ATOM   3483 O O   . TYR B 2 172 ? -2.203  -27.155 3.735   1   33.1   ? 168 TYR A O   1 
ATOM   3484 C CB  . TYR B 2 172 ? -1.397  -27.51  6.576   1   24.53  ? 168 TYR A CB  1 
ATOM   3485 C CG  . TYR B 2 172 ? -0.858  -28.246 7.784   1   23.63  ? 168 TYR A CG  1 
ATOM   3486 C CD1 . TYR B 2 172 ? -1.221  -29.564 8.014   1   24.21  ? 168 TYR A CD1 1 
ATOM   3487 C CD2 . TYR B 2 172 ? 0.113   -27.68  8.601   1   23.39  ? 168 TYR A CD2 1 
ATOM   3488 C CE1 . TYR B 2 172 ? -0.7    -30.289 9.072   1   24.18  ? 168 TYR A CE1 1 
ATOM   3489 C CE2 . TYR B 2 172 ? 0.654   -28.398 9.651   1   24.31  ? 168 TYR A CE2 1 
ATOM   3490 C CZ  . TYR B 2 172 ? 0.239   -29.699 9.897   1   25.09  ? 168 TYR A CZ  1 
ATOM   3491 O OH  . TYR B 2 172 ? 0.762   -30.435 10.921  1   27.56  ? 168 TYR A OH  1 
ATOM   3492 N N   . ARG B 2 173 ? -0.057  -26.424 3.405   1   31.15  ? 169 ARG A N   1 
ATOM   3493 C CA  . ARG B 2 173 ? -0.335  -25.535 2.284   1   28.36  ? 169 ARG A CA  1 
ATOM   3494 C C   . ARG B 2 173 ? -0.445  -26.327 0.985   1   27.35  ? 169 ARG A C   1 
ATOM   3495 O O   . ARG B 2 173 ? 0.472   -27.049 0.6     1   27.57  ? 169 ARG A O   1 
ATOM   3496 C CB  . ARG B 2 173 ? 0.748   -24.458 2.158   1   27.86  ? 169 ARG A CB  1 
ATOM   3497 C CG  . ARG B 2 173 ? 0.496   -23.444 1.046   1   26.51  ? 169 ARG A CG  1 
ATOM   3498 C CD  . ARG B 2 173 ? 1.617   -22.431 0.942   1   25.98  ? 169 ARG A CD  1 
ATOM   3499 N NE  . ARG B 2 173 ? 1.885   -21.853 2.261   1   25.74  ? 169 ARG A NE  1 
ATOM   3500 C CZ  . ARG B 2 173 ? 3.019   -21.271 2.618   1   26.82  ? 169 ARG A CZ  1 
ATOM   3501 N NH1 . ARG B 2 173 ? 3.972   -21.047 1.728   1   27.46  ? 169 ARG A NH1 1 
ATOM   3502 N NH2 . ARG B 2 173 ? 3.201   -20.918 3.876   1   26.89  ? 169 ARG A NH2 1 
ATOM   3503 N N   . ALA B 2 174 ? -1.584  -26.104 0.33    1   26.56  ? 170 ALA A N   1 
ATOM   3504 C CA  . ALA B 2 174 ? -2.027  -26.638 -0.949  1   26.52  ? 170 ALA A CA  1 
ATOM   3505 C C   . ALA B 2 174 ? -1.103  -26.267 -2.109  1   29.18  ? 170 ALA A C   1 
ATOM   3506 O O   . ALA B 2 174 ? -0.577  -25.149 -2.202  1   30.18  ? 170 ALA A O   1 
ATOM   3507 C CB  . ALA B 2 174 ? -3.4    -26.089 -1.22   1   25.47  ? 170 ALA A CB  1 
ATOM   3508 N N   . PRO B 2 175 ? -0.949  -27.181 -3.096  1   29.2   ? 171 PRO A N   1 
ATOM   3509 C CA  . PRO B 2 175 ? -0.027  -26.956 -4.216  1   28.09  ? 171 PRO A CA  1 
ATOM   3510 C C   . PRO B 2 175 ? -0.402  -25.764 -5.093  1   27.59  ? 171 PRO A C   1 
ATOM   3511 O O   . PRO B 2 175 ? 0.454   -25.137 -5.697  1   26.04  ? 171 PRO A O   1 
ATOM   3512 C CB  . PRO B 2 175 ? -0.017  -28.288 -4.993  1   28.79  ? 171 PRO A CB  1 
ATOM   3513 C CG  . PRO B 2 175 ? -1.257  -29.031 -4.529  1   29.54  ? 171 PRO A CG  1 
ATOM   3514 C CD  . PRO B 2 175 ? -1.632  -28.482 -3.152  1   28.34  ? 171 PRO A CD  1 
ATOM   3515 N N   . GLU B 2 176 ? -1.693  -25.438 -5.168  1   28.83  ? 172 GLU A N   1 
ATOM   3516 C CA  . GLU B 2 176 ? -2.077  -24.334 -6.031  1   30.05  ? 172 GLU A CA  1 
ATOM   3517 C C   . GLU B 2 176 ? -1.613  -23.023 -5.413  1   30.08  ? 172 GLU A C   1 
ATOM   3518 O O   . GLU B 2 176 ? -1.628  -22.011 -6.105  1   32.74  ? 172 GLU A O   1 
ATOM   3519 C CB  . GLU B 2 176 ? -3.558  -24.214 -6.385  1   29.76  ? 172 GLU A CB  1 
ATOM   3520 C CG  . GLU B 2 176 ? -4.491  -24.05  -5.191  1   29.51  ? 172 GLU A CG  1 
ATOM   3521 C CD  . GLU B 2 176 ? -4.986  -25.363 -4.592  1   29.38  ? 172 GLU A CD  1 
ATOM   3522 O OE1 . GLU B 2 176 ? -6.083  -25.35  -3.987  1   28.05  ? 172 GLU A OE1 1 
ATOM   3523 O OE2 . GLU B 2 176 ? -4.264  -26.392 -4.694  1   28.92  ? 172 GLU A OE2 1 
ATOM   3524 N N   . ILE B 2 177 ? -1.265  -23.049 -4.119  1   26.31  ? 173 ILE A N   1 
ATOM   3525 C CA  . ILE B 2 177 ? -0.713  -21.863 -3.492  1   26.04  ? 173 ILE A CA  1 
ATOM   3526 C C   . ILE B 2 177 ? 0.797   -21.874 -3.674  1   26.85  ? 173 ILE A C   1 
ATOM   3527 O O   . ILE B 2 177 ? 1.374   -20.849 -4.001  1   28.91  ? 173 ILE A O   1 
ATOM   3528 C CB  . ILE B 2 177 ? -1.113  -21.735 -2.013  1   26.24  ? 173 ILE A CB  1 
ATOM   3529 C CG1 . ILE B 2 177 ? -2.637  -21.848 -1.832  1   26.14  ? 173 ILE A CG1 1 
ATOM   3530 C CG2 . ILE B 2 177 ? -0.553  -20.435 -1.436  1   26.21  ? 173 ILE A CG2 1 
ATOM   3531 C CD1 . ILE B 2 177 ? -3.128  -21.847 -0.396  1   23.35  ? 173 ILE A CD1 1 
ATOM   3532 N N   . LEU B 2 178 ? 1.433   -23.039 -3.487  1   26.18  ? 174 LEU A N   1 
ATOM   3533 C CA  . LEU B 2 178 ? 2.879   -23.147 -3.631  1   25.93  ? 174 LEU A CA  1 
ATOM   3534 C C   . LEU B 2 178 ? 3.309   -22.794 -5.06   1   28.24  ? 174 LEU A C   1 
ATOM   3535 O O   . LEU B 2 178 ? 4.445   -22.386 -5.258  1   32.19  ? 174 LEU A O   1 
ATOM   3536 C CB  . LEU B 2 178 ? 3.323   -24.553 -3.238  1   24.19  ? 174 LEU A CB  1 
ATOM   3537 C CG  . LEU B 2 178 ? 3.195   -24.892 -1.751  1   23.25  ? 174 LEU A CG  1 
ATOM   3538 C CD1 . LEU B 2 178 ? 3.163   -26.395 -1.523  1   22.04  ? 174 LEU A CD1 1 
ATOM   3539 C CD2 . LEU B 2 178 ? 4.329   -24.265 -0.96   1   23.07  ? 174 LEU A CD2 1 
ATOM   3540 N N   . LEU B 2 179 ? 2.413   -22.948 -6.049  1   27.45  ? 175 LEU A N   1 
ATOM   3541 C CA  . LEU B 2 179 ? 2.699   -22.621 -7.433  1   28.62  ? 175 LEU A CA  1 
ATOM   3542 C C   . LEU B 2 179 ? 2.231   -21.194 -7.759  1   33.13  ? 175 LEU A C   1 
ATOM   3543 O O   . LEU B 2 179 ? 2.201   -20.78  -8.923  1   35.89  ? 175 LEU A O   1 
ATOM   3544 C CB  . LEU B 2 179 ? 2.039   -23.655 -8.343  1   28.06  ? 175 LEU A CB  1 
ATOM   3545 C CG  . LEU B 2 179 ? 2.591   -25.084 -8.293  1   26.87  ? 175 LEU A CG  1 
ATOM   3546 C CD1 . LEU B 2 179 ? 1.722   -26.095 -9.025  1   24.81  ? 175 LEU A CD1 1 
ATOM   3547 C CD2 . LEU B 2 179 ? 3.986   -25.093 -8.861  1   27.72  ? 175 LEU A CD2 1 
ATOM   3548 N N   . GLY B 2 180 ? 1.87    -20.41  -6.735  1   32.5   ? 176 GLY A N   1 
ATOM   3549 C CA  . GLY B 2 180 ? 1.531   -19.016 -6.955  1   32.64  ? 176 GLY A CA  1 
ATOM   3550 C C   . GLY B 2 180 ? 0.422   -18.869 -7.992  1   34.23  ? 176 GLY A C   1 
ATOM   3551 O O   . GLY B 2 180 ? 0.519   -18.072 -8.92   1   35.49  ? 176 GLY A O   1 
ATOM   3552 N N   . CYS B 2 181 ? -0.639  -19.66  -7.833  1   36.84  ? 177 CYS A N   1 
ATOM   3553 C CA  . CYS B 2 181 ? -1.798  -19.53  -8.702  1   39.27  ? 177 CYS A CA  1 
ATOM   3554 C C   . CYS B 2 181 ? -2.484  -18.208 -8.388  1   37.45  ? 177 CYS A C   1 
ATOM   3555 O O   . CYS B 2 181 ? -2.365  -17.681 -7.28   1   35.82  ? 177 CYS A O   1 
ATOM   3556 C CB  . CYS B 2 181 ? -2.739  -20.733 -8.611  1   43.78  ? 177 CYS A CB  1 
ATOM   3557 S SG  . CYS B 2 181 ? -2.25   -22.15  -9.648  1   48.84  ? 177 CYS A SG  1 
ATOM   3558 N N   . LYS B 2 182 ? -3.14   -17.665 -9.413  1   37.02  ? 178 LYS A N   1 
ATOM   3559 C CA  . LYS B 2 182 ? -3.735  -16.351 -9.297  1   37.39  ? 178 LYS A CA  1 
ATOM   3560 C C   . LYS B 2 182 ? -4.897  -16.451 -8.313  1   36.64  ? 178 LYS A C   1 
ATOM   3561 O O   . LYS B 2 182 ? -5.129  -15.545 -7.512  1   34.41  ? 178 LYS A O   1 
ATOM   3562 C CB  . LYS B 2 182 ? -4.081  -15.911 -10.719 1   38.49  ? 178 LYS A CB  1 
ATOM   3563 C CG  . LYS B 2 182 ? -4.805  -14.589 -10.83  1   43.43  ? 178 LYS A CG  1 
ATOM   3564 C CD  . LYS B 2 182 ? -5.246  -14.321 -12.265 1   49.99  ? 178 LYS A CD  1 
ATOM   3565 C CE  . LYS B 2 182 ? -5.745  -12.924 -12.491 1   57.1   ? 178 LYS A CE  1 
ATOM   3566 N NZ  . LYS B 2 182 ? -6.632  -12.871 -13.66  1   61.92  ? 178 LYS A NZ  1 
ATOM   3567 N N   . TYR B 2 183 ? -5.595  -17.598 -8.371  1   36.8   ? 179 TYR A N   1 
ATOM   3568 C CA  . TYR B 2 183 ? -6.846  -17.79  -7.649  1   34.84  ? 179 TYR A CA  1 
ATOM   3569 C C   . TYR B 2 183 ? -6.765  -19.069 -6.822  1   32.37  ? 179 TYR A C   1 
ATOM   3570 O O   . TYR B 2 183 ? -6.248  -20.095 -7.301  1   30.9   ? 179 TYR A O   1 
ATOM   3571 C CB  . TYR B 2 183 ? -8.003  -17.997 -8.625  1   34.07  ? 179 TYR A CB  1 
ATOM   3572 C CG  . TYR B 2 183 ? -8.366  -16.788 -9.462  1   35.72  ? 179 TYR A CG  1 
ATOM   3573 C CD1 . TYR B 2 183 ? -8.712  -15.566 -8.882  1   38.79  ? 179 TYR A CD1 1 
ATOM   3574 C CD2 . TYR B 2 183 ? -8.352  -16.875 -10.838 1   35.39  ? 179 TYR A CD2 1 
ATOM   3575 C CE1 . TYR B 2 183 ? -9.045  -14.462 -9.652  1   39.93  ? 179 TYR A CE1 1 
ATOM   3576 C CE2 . TYR B 2 183 ? -8.671  -15.779 -11.618 1   38.3   ? 179 TYR A CE2 1 
ATOM   3577 C CZ  . TYR B 2 183 ? -9.014  -14.576 -11.034 1   40.74  ? 179 TYR A CZ  1 
ATOM   3578 O OH  . TYR B 2 183 ? -9.341  -13.558 -11.891 1   44.15  ? 179 TYR A OH  1 
ATOM   3579 N N   . TYR B 2 184 ? -7.262  -18.972 -5.576  1   29.6   ? 180 TYR A N   1 
ATOM   3580 C CA  . TYR B 2 184 ? -7.463  -20.149 -4.751  1   27.9   ? 180 TYR A CA  1 
ATOM   3581 C C   . TYR B 2 184 ? -8.837  -20.059 -4.084  1   27.44  ? 180 TYR A C   1 
ATOM   3582 O O   . TYR B 2 184 ? -9.372  -18.961 -3.881  1   26.41  ? 180 TYR A O   1 
ATOM   3583 C CB  . TYR B 2 184 ? -6.256  -20.477 -3.863  1   26.2   ? 180 TYR A CB  1 
ATOM   3584 C CG  . TYR B 2 184 ? -6.024  -19.434 -2.788  1   27.12  ? 180 TYR A CG  1 
ATOM   3585 C CD1 . TYR B 2 184 ? -6.849  -19.374 -1.661  1   26.59  ? 180 TYR A CD1 1 
ATOM   3586 C CD2 . TYR B 2 184 ? -4.952  -18.553 -2.877  1   28.91  ? 180 TYR A CD2 1 
ATOM   3587 C CE1 . TYR B 2 184 ? -6.629  -18.438 -0.661  1   29.15  ? 180 TYR A CE1 1 
ATOM   3588 C CE2 . TYR B 2 184 ? -4.727  -17.605 -1.887  1   32.05  ? 180 TYR A CE2 1 
ATOM   3589 C CZ  . TYR B 2 184 ? -5.574  -17.542 -0.785  1   32.83  ? 180 TYR A CZ  1 
ATOM   3590 O OH  . TYR B 2 184 ? -5.36   -16.597 0.177   1   35.1   ? 180 TYR A OH  1 
ATOM   3591 N N   . SER B 2 185 ? -9.388  -21.245 -3.767  1   25.36  ? 181 SER A N   1 
ATOM   3592 C CA  . SER B 2 185 ? -10.737 -21.374 -3.253  1   25.48  ? 181 SER A CA  1 
ATOM   3593 C C   . SER B 2 185 ? -10.785 -22.293 -2.035  1   25.5   ? 181 SER A C   1 
ATOM   3594 O O   . SER B 2 185 ? -9.781  -22.572 -1.381  1   26.22  ? 181 SER A O   1 
ATOM   3595 C CB  . SER B 2 185 ? -11.634 -21.902 -4.338  1   27.28  ? 181 SER A CB  1 
ATOM   3596 O OG  . SER B 2 185 ? -12.994 -21.517 -4.14   1   30.76  ? 181 SER A OG  1 
ATOM   3597 N N   . THR B 2 186 ? -12     -22.762 -1.758  1   26.27  ? 182 THR A N   1 
ATOM   3598 C CA  . THR B 2 186 ? -12.351 -23.631 -0.648  1   25.43  ? 182 THR A CA  1 
ATOM   3599 C C   . THR B 2 186 ? -11.429 -24.844 -0.603  1   25.15  ? 182 THR A C   1 
ATOM   3600 O O   . THR B 2 186 ? -11.232 -25.429 0.457   1   23.41  ? 182 THR A O   1 
ATOM   3601 C CB  . THR B 2 186 ? -13.808 -24.063 -0.82   1   26.55  ? 182 THR A CB  1 
ATOM   3602 O OG1 . THR B 2 186 ? -14.057 -24.269 -2.207  1   30.86  ? 182 THR A OG1 1 
ATOM   3603 C CG2 . THR B 2 186 ? -14.794 -23.008 -0.377  1   23.64  ? 182 THR A CG2 1 
ATOM   3604 N N   . ALA B 2 187 ? -10.879 -25.229 -1.76   1   26.95  ? 183 ALA A N   1 
ATOM   3605 C CA  . ALA B 2 187 ? -10.081 -26.445 -1.859  1   26     ? 183 ALA A CA  1 
ATOM   3606 C C   . ALA B 2 187 ? -8.803  -26.349 -1.016  1   25.91  ? 183 ALA A C   1 
ATOM   3607 O O   . ALA B 2 187 ? -8.252  -27.371 -0.614  1   27.25  ? 183 ALA A O   1 
ATOM   3608 C CB  . ALA B 2 187 ? -9.797  -26.757 -3.306  1   22.55  ? 183 ALA A CB  1 
ATOM   3609 N N   . VAL B 2 188 ? -8.311  -25.133 -0.747  1   24.25  ? 184 VAL A N   1 
ATOM   3610 C CA  . VAL B 2 188 ? -7.078  -25.028 0.019   1   24.89  ? 184 VAL A CA  1 
ATOM   3611 C C   . VAL B 2 188 ? -7.294  -25.587 1.434   1   24.9   ? 184 VAL A C   1 
ATOM   3612 O O   . VAL B 2 188 ? -6.372  -26.136 2.038   1   22.42  ? 184 VAL A O   1 
ATOM   3613 C CB  . VAL B 2 188 ? -6.52   -23.597 0.038   1   24.72  ? 184 VAL A CB  1 
ATOM   3614 C CG1 . VAL B 2 188 ? -6.499  -23.002 -1.362  1   26.72  ? 184 VAL A CG1 1 
ATOM   3615 C CG2 . VAL B 2 188 ? -7.306  -22.694 0.968   1   23.04  ? 184 VAL A CG2 1 
ATOM   3616 N N   . ASP B 2 189 ? -8.529  -25.454 1.949   1   24.68  ? 185 ASP A N   1 
ATOM   3617 C CA  . ASP B 2 189 ? -8.87   -25.926 3.28    1   24.22  ? 185 ASP A CA  1 
ATOM   3618 C C   . ASP B 2 189 ? -9.014  -27.436 3.237   1   26.95  ? 185 ASP A C   1 
ATOM   3619 O O   . ASP B 2 189 ? -8.535  -28.108 4.14    1   30.78  ? 185 ASP A O   1 
ATOM   3620 C CB  . ASP B 2 189 ? -10.132 -25.298 3.835   1   24.35  ? 185 ASP A CB  1 
ATOM   3621 C CG  . ASP B 2 189 ? -10.021 -23.831 4.227   1   26.46  ? 185 ASP A CG  1 
ATOM   3622 O OD1 . ASP B 2 189 ? -8.871  -23.412 4.509   1   25.33  ? 185 ASP A OD1 1 
ATOM   3623 O OD2 . ASP B 2 189 ? -11.087 -23.114 4.229   1   27.09  ? 185 ASP A OD2 1 
ATOM   3624 N N   . ILE B 2 190 ? -9.65   -27.975 2.19    1   26.87  ? 186 ILE A N   1 
ATOM   3625 C CA  . ILE B 2 190 ? -9.78   -29.419 2.107   1   26.83  ? 186 ILE A CA  1 
ATOM   3626 C C   . ILE B 2 190 ? -8.385  -30.052 2.076   1   30.24  ? 186 ILE A C   1 
ATOM   3627 O O   . ILE B 2 190 ? -8.179  -31.09  2.709   1   35.3   ? 186 ILE A O   1 
ATOM   3628 C CB  . ILE B 2 190 ? -10.714 -29.849 0.96    1   24.83  ? 186 ILE A CB  1 
ATOM   3629 C CG1 . ILE B 2 190 ? -12.17  -29.619 1.335   1   23.97  ? 186 ILE A CG1 1 
ATOM   3630 C CG2 . ILE B 2 190 ? -10.483 -31.304 0.566   1   23.77  ? 186 ILE A CG2 1 
ATOM   3631 C CD1 . ILE B 2 190 ? -12.725 -30.612 2.338   1   23.77  ? 186 ILE A CD1 1 
ATOM   3632 N N   . TRP B 2 191 ? -7.421  -29.425 1.376   1   28.1   ? 187 TRP A N   1 
ATOM   3633 C CA  . TRP B 2 191 ? -6.062  -29.957 1.352   1   27.6   ? 187 TRP A CA  1 
ATOM   3634 C C   . TRP B 2 191 ? -5.55   -30.115 2.789   1   28.31  ? 187 TRP A C   1 
ATOM   3635 O O   . TRP B 2 191 ? -5.231  -31.219 3.238   1   28.57  ? 187 TRP A O   1 
ATOM   3636 C CB  . TRP B 2 191 ? -5.128  -29.08  0.507   1   25.58  ? 187 TRP A CB  1 
ATOM   3637 C CG  . TRP B 2 191 ? -3.714  -29.598 0.413   1   27.02  ? 187 TRP A CG  1 
ATOM   3638 C CD1 . TRP B 2 191 ? -2.683  -29.327 1.271   1   28.83  ? 187 TRP A CD1 1 
ATOM   3639 C CD2 . TRP B 2 191 ? -3.164  -30.476 -0.596  1   27.4   ? 187 TRP A CD2 1 
ATOM   3640 N NE1 . TRP B 2 191 ? -1.533  -29.97  0.874   1   28.97  ? 187 TRP A NE1 1 
ATOM   3641 C CE2 . TRP B 2 191 ? -1.802  -30.677 -0.275  1   28.7   ? 187 TRP A CE2 1 
ATOM   3642 C CE3 . TRP B 2 191 ? -3.675  -31.1   -1.735  1   26.16  ? 187 TRP A CE3 1 
ATOM   3643 C CZ2 . TRP B 2 191 ? -0.968  -31.464 -1.073  1   28.51  ? 187 TRP A CZ2 1 
ATOM   3644 C CZ3 . TRP B 2 191 ? -2.842  -31.878 -2.509  1   26.24  ? 187 TRP A CZ3 1 
ATOM   3645 C CH2 . TRP B 2 191 ? -1.507  -32.066 -2.187  1   25.81  ? 187 TRP A CH2 1 
ATOM   3646 N N   . SER B 2 192 ? -5.509  -28.992 3.508   1   25.79  ? 188 SER A N   1 
ATOM   3647 C CA  . SER B 2 192 ? -5.178  -28.975 4.917   1   25.53  ? 188 SER A CA  1 
ATOM   3648 C C   . SER B 2 192 ? -5.839  -30.143 5.67    1   25.46  ? 188 SER A C   1 
ATOM   3649 O O   . SER B 2 192 ? -5.144  -30.919 6.309   1   26.11  ? 188 SER A O   1 
ATOM   3650 C CB  . SER B 2 192 ? -5.48   -27.608 5.521   1   24.12  ? 188 SER A CB  1 
ATOM   3651 O OG  . SER B 2 192 ? -4.707  -26.592 4.893   1   22.62  ? 188 SER A OG  1 
ATOM   3652 N N   . LEU B 2 193 ? -7.163  -30.319 5.572   1   25.6   ? 189 LEU A N   1 
ATOM   3653 C CA  . LEU B 2 193 ? -7.854  -31.35  6.342   1   26.92  ? 189 LEU A CA  1 
ATOM   3654 C C   . LEU B 2 193 ? -7.325  -32.735 5.985   1   27.92  ? 189 LEU A C   1 
ATOM   3655 O O   . LEU B 2 193 ? -7.389  -33.638 6.827   1   29.09  ? 189 LEU A O   1 
ATOM   3656 C CB  . LEU B 2 193 ? -9.367  -31.355 6.123   1   25.56  ? 189 LEU A CB  1 
ATOM   3657 C CG  . LEU B 2 193 ? -10.195 -30.385 6.962   1   26.03  ? 189 LEU A CG  1 
ATOM   3658 C CD1 . LEU B 2 193 ? -11.651 -30.848 6.878   1   25.59  ? 189 LEU A CD1 1 
ATOM   3659 C CD2 . LEU B 2 193 ? -9.702  -30.303 8.409   1   25.76  ? 189 LEU A CD2 1 
ATOM   3660 N N   . GLY B 2 194 ? -6.928  -32.898 4.711   1   25.24  ? 190 GLY A N   1 
ATOM   3661 C CA  . GLY B 2 194 ? -6.348  -34.128 4.2     1   24.86  ? 190 GLY A CA  1 
ATOM   3662 C C   . GLY B 2 194 ? -4.986  -34.432 4.821   1   25.15  ? 190 GLY A C   1 
ATOM   3663 O O   . GLY B 2 194 ? -4.736  -35.554 5.23    1   25.95  ? 190 GLY A O   1 
ATOM   3664 N N   . CYS B 2 195 ? -4.115  -33.419 4.905   1   24.65  ? 191 CYS A N   1 
ATOM   3665 C CA  . CYS B 2 195 ? -2.87   -33.521 5.634   1   22.98  ? 191 CYS A CA  1 
ATOM   3666 C C   . CYS B 2 195 ? -3.134  -33.908 7.083   1   23.05  ? 191 CYS A C   1 
ATOM   3667 O O   . CYS B 2 195 ? -2.409  -34.731 7.634   1   25.84  ? 191 CYS A O   1 
ATOM   3668 C CB  . CYS B 2 195 ? -2.137  -32.194 5.574   1   24.42  ? 191 CYS A CB  1 
ATOM   3669 S SG  . CYS B 2 195 ? -1.529  -31.827 3.91    1   31.91  ? 191 CYS A SG  1 
ATOM   3670 N N   . ILE B 2 196 ? -4.159  -33.335 7.702   1   20.52  ? 192 ILE A N   1 
ATOM   3671 C CA  . ILE B 2 196 ? -4.455  -33.578 9.145   1   20.61  ? 192 ILE A CA  1 
ATOM   3672 C C   . ILE B 2 196 ? -5.013  -34.995 9.351   1   22.8   ? 192 ILE A C   1 
ATOM   3673 O O   . ILE B 2 196 ? -4.668  -35.621 10.36   1   23.03  ? 192 ILE A O   1 
ATOM   3674 C CB  . ILE B 2 196 ? -5.407  -32.485 9.666   1   18.92  ? 192 ILE A CB  1 
ATOM   3675 C CG1 . ILE B 2 196 ? -4.725  -31.126 9.727   1   18     ? 192 ILE A CG1 1 
ATOM   3676 C CG2 . ILE B 2 196 ? -6.019  -32.864 11.014  1   18.32  ? 192 ILE A CG2 1 
ATOM   3677 C CD1 . ILE B 2 196 ? -5.686  -29.963 9.596   1   16.54  ? 192 ILE A CD1 1 
ATOM   3678 N N   . PHE B 2 197 ? -5.831  -35.48  8.425   1   22.79  ? 193 PHE A N   1 
ATOM   3679 C CA  . PHE B 2 197 ? -6.371  -36.856 8.508   1   23.17  ? 193 PHE A CA  1 
ATOM   3680 C C   . PHE B 2 197 ? -5.215  -37.792 8.579   1   25.58  ? 193 PHE A C   1 
ATOM   3681 O O   . PHE B 2 197 ? -5.112  -38.561 9.541   1   27.08  ? 193 PHE A O   1 
ATOM   3682 C CB  . PHE B 2 197 ? -7.219  -37.058 7.252   1   23.02  ? 193 PHE A CB  1 
ATOM   3683 C CG  . PHE B 2 197 ? -7.852  -38.425 7.037   1   27.11  ? 193 PHE A CG  1 
ATOM   3684 C CD1 . PHE B 2 197 ? -7.976  -39.34  8.074   1   27.63  ? 193 PHE A CD1 1 
ATOM   3685 C CD2 . PHE B 2 197 ? -8.336  -38.787 5.787   1   28.42  ? 193 PHE A CD2 1 
ATOM   3686 C CE1 . PHE B 2 197 ? -8.552  -40.58  7.861   1   29.35  ? 193 PHE A CE1 1 
ATOM   3687 C CE2 . PHE B 2 197 ? -8.918  -40.025 5.583   1   30.12  ? 193 PHE A CE2 1 
ATOM   3688 C CZ  . PHE B 2 197 ? -9.023  -40.917 6.618   1   30.4   ? 193 PHE A CZ  1 
ATOM   3689 N N   . ALA B 2 198 ? -4.369  -37.748 7.56    1   24.89  ? 194 ALA A N   1 
ATOM   3690 C CA  . ALA B 2 198 ? -3.16   -38.587 7.539   1   26.23  ? 194 ALA A CA  1 
ATOM   3691 C C   . ALA B 2 198 ? -2.39   -38.375 8.833   1   27.96  ? 194 ALA A C   1 
ATOM   3692 O O   . ALA B 2 198 ? -1.968  -39.356 9.451   1   28.04  ? 194 ALA A O   1 
ATOM   3693 C CB  . ALA B 2 198 ? -2.343  -38.19  6.355   1   25.7   ? 194 ALA A CB  1 
ATOM   3694 N N   . GLU B 2 199 ? -2.25   -37.117 9.239   1   27.97  ? 195 GLU A N   1 
ATOM   3695 C CA  . GLU B 2 199 ? -1.46   -36.85  10.429  1   29.75  ? 195 GLU A CA  1 
ATOM   3696 C C   . GLU B 2 199 ? -2.106  -37.468 11.68   1   30.95  ? 195 GLU A C   1 
ATOM   3697 O O   . GLU B 2 199 ? -1.392  -37.853 12.608  1   32.18  ? 195 GLU A O   1 
ATOM   3698 C CB  . GLU B 2 199 ? -1.204  -35.349 10.554  1   28.3   ? 195 GLU A CB  1 
ATOM   3699 C CG  . GLU B 2 199 ? -0.262  -35.047 11.714  1   28.91  ? 195 GLU A CG  1 
ATOM   3700 C CD  . GLU B 2 199 ? 0.264   -33.645 11.809  1   28.43  ? 195 GLU A CD  1 
ATOM   3701 O OE1 . GLU B 2 199 ? -0.04   -32.863 10.89   1   27.1   ? 195 GLU A OE1 1 
ATOM   3702 O OE2 . GLU B 2 199 ? 0.983   -33.372 12.804  1   30.79  ? 195 GLU A OE2 1 
ATOM   3703 N N   . MET B 2 200 ? -3.443  -37.574 11.714  1   28.78  ? 196 MET A N   1 
ATOM   3704 C CA  . MET B 2 200 ? -4.079  -38.255 12.833  1   29.99  ? 196 MET A CA  1 
ATOM   3705 C C   . MET B 2 200 ? -3.7    -39.739 12.863  1   31.51  ? 196 MET A C   1 
ATOM   3706 O O   . MET B 2 200 ? -3.486  -40.303 13.932  1   32.61  ? 196 MET A O   1 
ATOM   3707 C CB  . MET B 2 200 ? -5.6    -38.075 12.85   1   28.9   ? 196 MET A CB  1 
ATOM   3708 C CG  . MET B 2 200 ? -6.047  -36.76  13.426  1   26.97  ? 196 MET A CG  1 
ATOM   3709 S SD  . MET B 2 200 ? -7.832  -36.554 13.551  1   25.09  ? 196 MET A SD  1 
ATOM   3710 C CE  . MET B 2 200 ? -8.421  -36.828 11.88   1   23.52  ? 196 MET A CE  1 
ATOM   3711 N N   . VAL B 2 201 ? -3.563  -40.354 11.685  1   31.33  ? 197 VAL A N   1 
ATOM   3712 C CA  . VAL B 2 201 ? -3.358  -41.795 11.603  1   33.34  ? 197 VAL A CA  1 
ATOM   3713 C C   . VAL B 2 201 ? -1.952  -42.18  12.05   1   35.04  ? 197 VAL A C   1 
ATOM   3714 O O   . VAL B 2 201 ? -1.785  -43.193 12.726  1   36.58  ? 197 VAL A O   1 
ATOM   3715 C CB  . VAL B 2 201 ? -3.671  -42.297 10.18   1   33.7   ? 197 VAL A CB  1 
ATOM   3716 C CG1 . VAL B 2 201 ? -3.437  -43.79  10.031  1   33.99  ? 197 VAL A CG1 1 
ATOM   3717 C CG2 . VAL B 2 201 ? -5.108  -41.943 9.796   1   34.32  ? 197 VAL A CG2 1 
ATOM   3718 N N   . THR B 2 202 ? -0.963  -41.347 11.676  1   37.01  ? 198 THR A N   1 
ATOM   3719 C CA  . THR B 2 202 ? 0.466   -41.614 11.839  1   37.6   ? 198 THR A CA  1 
ATOM   3720 C C   . THR B 2 202 ? 1.068   -40.802 12.994  1   39.71  ? 198 THR A C   1 
ATOM   3721 O O   . THR B 2 202 ? 2.115   -41.156 13.536  1   39.92  ? 198 THR A O   1 
ATOM   3722 C CB  . THR B 2 202 ? 1.217   -41.271 10.558  1   34.94  ? 198 THR A CB  1 
ATOM   3723 O OG1 . THR B 2 202 ? 1.202   -39.849 10.549  1   35.83  ? 198 THR A OG1 1 
ATOM   3724 C CG2 . THR B 2 202 ? 0.587   -41.813 9.297   1   33     ? 198 THR A CG2 1 
ATOM   3725 N N   . ARG B 2 203 ? 0.435   -39.677 13.338  1   41.19  ? 199 ARG A N   1 
ATOM   3726 C CA  . ARG B 2 203 ? 0.938   -38.802 14.389  1   45.97  ? 199 ARG A CA  1 
ATOM   3727 C C   . ARG B 2 203 ? 2.231   -38.116 13.942  1   47.62  ? 199 ARG A C   1 
ATOM   3728 O O   . ARG B 2 203 ? 2.931   -37.532 14.774  1   52.43  ? 199 ARG A O   1 
ATOM   3729 C CB  . ARG B 2 203 ? 1.094   -39.508 15.744  1   47.74  ? 199 ARG A CB  1 
ATOM   3730 C CG  . ARG B 2 203 ? -0.22   -39.67  16.493  1   49.06  ? 199 ARG A CG  1 
ATOM   3731 C CD  . ARG B 2 203 ? -0.237  -40.89  17.388  1   51.01  ? 199 ARG A CD  1 
ATOM   3732 N NE  . ARG B 2 203 ? -0.102  -42.087 16.549  1   56.39  ? 199 ARG A NE  1 
ATOM   3733 C CZ  . ARG B 2 203 ? 0.956   -42.897 16.557  1   60.16  ? 199 ARG A CZ  1 
ATOM   3734 N NH1 . ARG B 2 203 ? 1.989   -42.609 17.347  1   60.38  ? 199 ARG A NH1 1 
ATOM   3735 N NH2 . ARG B 2 203 ? 0.965   -43.981 15.784  1   59.49  ? 199 ARG A NH2 1 
ATOM   3736 N N   . ARG B 2 204 ? 2.51    -38.147 12.631  1   43.12  ? 200 ARG A N   1 
ATOM   3737 C CA  . ARG B 2 204 ? 3.547   -37.301 12.07   1   44.82  ? 200 ARG A CA  1 
ATOM   3738 C C   . ARG B 2 204 ? 3.065   -36.593 10.799  1   42.88  ? 200 ARG A C   1 
ATOM   3739 O O   . ARG B 2 204 ? 2.201   -37.09  10.076  1   41.55  ? 200 ARG A O   1 
ATOM   3740 C CB  . ARG B 2 204 ? 4.819   -38.122 11.869  1   48.3   ? 200 ARG A CB  1 
ATOM   3741 C CG  . ARG B 2 204 ? 4.613   -39.259 10.888  1   50.09  ? 200 ARG A CG  1 
ATOM   3742 C CD  . ARG B 2 204 ? 5.907   -39.594 10.169  1   55.58  ? 200 ARG A CD  1 
ATOM   3743 N NE  . ARG B 2 204 ? 5.543   -40.332 8.959   1   56.22  ? 200 ARG A NE  1 
ATOM   3744 C CZ  . ARG B 2 204 ? 6.375   -41.088 8.262   1   64.42  ? 200 ARG A CZ  1 
ATOM   3745 N NH1 . ARG B 2 204 ? 7.654   -41.191 8.607   1   68.38  ? 200 ARG A NH1 1 
ATOM   3746 N NH2 . ARG B 2 204 ? 5.909   -41.756 7.222   1   67.9   ? 200 ARG A NH2 1 
ATOM   3747 N N   . ALA B 2 205 ? 3.643   -35.419 10.526  1   40.13  ? 201 ALA A N   1 
ATOM   3748 C CA  . ALA B 2 205 ? 3.139   -34.631 9.414   1   37.57  ? 201 ALA A CA  1 
ATOM   3749 C C   . ALA B 2 205 ? 3.449   -35.365 8.111   1   35.21  ? 201 ALA A C   1 
ATOM   3750 O O   . ALA B 2 205 ? 4.488   -36.014 8.006   1   37.13  ? 201 ALA A O   1 
ATOM   3751 C CB  . ALA B 2 205 ? 3.69    -33.219 9.444   1   35.59  ? 201 ALA A CB  1 
ATOM   3752 N N   . LEU B 2 206 ? 2.516   -35.259 7.157   1   30.18  ? 202 LEU A N   1 
ATOM   3753 C CA  . LEU B 2 206 ? 2.536   -35.969 5.895   1   29.45  ? 202 LEU A CA  1 
ATOM   3754 C C   . LEU B 2 206 ? 3.58    -35.351 4.963   1   30.56  ? 202 LEU A C   1 
ATOM   3755 O O   . LEU B 2 206 ? 4.275   -36.064 4.233   1   31.68  ? 202 LEU A O   1 
ATOM   3756 C CB  . LEU B 2 206 ? 1.118   -35.866 5.321   1   27.71  ? 202 LEU A CB  1 
ATOM   3757 C CG  . LEU B 2 206 ? 0.869   -36.508 3.947   1   26.31  ? 202 LEU A CG  1 
ATOM   3758 C CD1 . LEU B 2 206 ? 1.002   -38.006 4.011   1   28.16  ? 202 LEU A CD1 1 
ATOM   3759 C CD2 . LEU B 2 206 ? -0.485  -36.141 3.428   1   23.58  ? 202 LEU A CD2 1 
ATOM   3760 N N   . PHE B 2 207 ? 3.649   -34.014 4.962   1   28.99  ? 203 PHE A N   1 
ATOM   3761 C CA  . PHE B 2 207 ? 4.608   -33.31  4.131   1   28.2   ? 203 PHE A CA  1 
ATOM   3762 C C   . PHE B 2 207 ? 5.323   -32.232 4.945   1   29.17  ? 203 PHE A C   1 
ATOM   3763 O O   . PHE B 2 207 ? 4.978   -31.051 4.842   1   28.77  ? 203 PHE A O   1 
ATOM   3764 C CB  . PHE B 2 207 ? 3.864   -32.595 3.015   1   27.78  ? 203 PHE A CB  1 
ATOM   3765 C CG  . PHE B 2 207 ? 2.963   -33.456 2.166   1   29.35  ? 203 PHE A CG  1 
ATOM   3766 C CD1 . PHE B 2 207 ? 3.448   -34.612 1.564   1   33.04  ? 203 PHE A CD1 1 
ATOM   3767 C CD2 . PHE B 2 207 ? 1.627   -33.093 1.978   1   29.85  ? 203 PHE A CD2 1 
ATOM   3768 C CE1 . PHE B 2 207 ? 2.594   -35.396 0.779   1   36.19  ? 203 PHE A CE1 1 
ATOM   3769 C CE2 . PHE B 2 207 ? 0.779   -33.873 1.203   1   30.87  ? 203 PHE A CE2 1 
ATOM   3770 C CZ  . PHE B 2 207 ? 1.262   -35.021 0.58    1   33.16  ? 203 PHE A CZ  1 
ATOM   3771 N N   . PRO B 2 208 ? 6.376   -32.616 5.725   1   29.67  ? 204 PRO A N   1 
ATOM   3772 C CA  . PRO B 2 208 ? 7.106   -31.68  6.564   1   28.94  ? 204 PRO A CA  1 
ATOM   3773 C C   . PRO B 2 208 ? 8.247   -30.961 5.868   1   30.45  ? 204 PRO A C   1 
ATOM   3774 O O   . PRO B 2 208 ? 9.416   -31.225 6.157   1   30.9   ? 204 PRO A O   1 
ATOM   3775 C CB  . PRO B 2 208 ? 7.571   -32.606 7.679   1   28.66  ? 204 PRO A CB  1 
ATOM   3776 C CG  . PRO B 2 208 ? 7.935   -33.89  7.003   1   28.5   ? 204 PRO A CG  1 
ATOM   3777 C CD  . PRO B 2 208 ? 6.971   -33.969 5.857   1   28.03  ? 204 PRO A CD  1 
ATOM   3778 N N   . GLY B 2 209 ? 7.906   -29.998 5.019   1   31.61  ? 205 GLY A N   1 
ATOM   3779 C CA  . GLY B 2 209 ? 8.903   -29.271 4.225   1   34.08  ? 205 GLY A CA  1 
ATOM   3780 C C   . GLY B 2 209 ? 9.66    -28.213 4.977   1   37.49  ? 205 GLY A C   1 
ATOM   3781 O O   . GLY B 2 209 ? 9.131   -27.697 5.973   1   38.84  ? 205 GLY A O   1 
ATOM   3782 N N   . ASP B 2 210 ? 10.845  -27.873 4.477   1   39.89  ? 206 ASP A N   1 
ATOM   3783 C CA  . ASP B 2 210 ? 11.734  -26.893 5.146   1   43.73  ? 206 ASP A CA  1 
ATOM   3784 C C   . ASP B 2 210 ? 11.723  -25.62  4.314   1   42.04  ? 206 ASP A C   1 
ATOM   3785 O O   . ASP B 2 210 ? 12.231  -24.592 4.777   1   46.37  ? 206 ASP A O   1 
ATOM   3786 C CB  . ASP B 2 210 ? 13.131  -27.471 5.257   1   48.59  ? 206 ASP A CB  1 
ATOM   3787 C CG  . ASP B 2 210 ? 13.205  -28.921 5.71    1   54.75  ? 206 ASP A CG  1 
ATOM   3788 O OD1 . ASP B 2 210 ? 12.831  -29.192 6.867   1   56.42  ? 206 ASP A OD1 1 
ATOM   3789 O OD2 . ASP B 2 210 ? 13.638  -29.767 4.904   1   53.48  ? 206 ASP A OD2 1 
ATOM   3790 N N   . SER B 2 211 ? 11.137  -25.708 3.13    1   36.75  ? 207 SER A N   1 
ATOM   3791 C CA  . SER B 2 211 ? 11.073  -24.553 2.217   1   35.2   ? 207 SER A CA  1 
ATOM   3792 C C   . SER B 2 211 ? 9.85    -24.737 1.326   1   34.5   ? 207 SER A C   1 
ATOM   3793 O O   . SER B 2 211 ? 9.273   -25.826 1.346   1   34.01  ? 207 SER A O   1 
ATOM   3794 C CB  . SER B 2 211 ? 12.314  -24.477 1.407   1   35.79  ? 207 SER A CB  1 
ATOM   3795 O OG  . SER B 2 211 ? 12.241  -25.319 0.269   1   36.61  ? 207 SER A OG  1 
ATOM   3796 N N   . GLU B 2 212 ? 9.489   -23.71  0.574   1   33.35  ? 208 GLU A N   1 
ATOM   3797 C CA  . GLU B 2 212 ? 8.369   -23.841 -0.376  1   31.28  ? 208 GLU A CA  1 
ATOM   3798 C C   . GLU B 2 212 ? 8.737   -24.847 -1.477  1   30.27  ? 208 GLU A C   1 
ATOM   3799 O O   . GLU B 2 212 ? 7.841   -25.577 -1.912  1   28.84  ? 208 GLU A O   1 
ATOM   3800 C CB  . GLU B 2 212 ? 8.045   -22.469 -0.955  1   32.82  ? 208 GLU A CB  1 
ATOM   3801 C CG  . GLU B 2 212 ? 7.603   -21.435 0.071   1   35.98  ? 208 GLU A CG  1 
ATOM   3802 C CD  . GLU B 2 212 ? 7.196   -20.176 -0.665  1   37.99  ? 208 GLU A CD  1 
ATOM   3803 O OE1 . GLU B 2 212 ? 6.398   -20.297 -1.612  1   36.38  ? 208 GLU A OE1 1 
ATOM   3804 O OE2 . GLU B 2 212 ? 7.68    -19.087 -0.311  1   42.29  ? 208 GLU A OE2 1 
ATOM   3805 N N   . ILE B 2 213 ? 9.988   -24.869 -1.937  1   29.37  ? 209 ILE A N   1 
ATOM   3806 C CA  . ILE B 2 213 ? 10.292  -25.795 -3.005  1   29.58  ? 209 ILE A CA  1 
ATOM   3807 C C   . ILE B 2 213 ? 10.406  -27.213 -2.431  1   30.84  ? 209 ILE A C   1 
ATOM   3808 O O   . ILE B 2 213 ? 10.093  -28.212 -3.099  1   28.56  ? 209 ILE A O   1 
ATOM   3809 C CB  . ILE B 2 213 ? 11.535  -25.346 -3.794  1   29.67  ? 209 ILE A CB  1 
ATOM   3810 C CG1 . ILE B 2 213 ? 11.548  -25.981 -5.176  1   28.42  ? 209 ILE A CG1 1 
ATOM   3811 C CG2 . ILE B 2 213 ? 12.828  -25.591 -3.018  1   30.54  ? 209 ILE A CG2 1 
ATOM   3812 C CD1 . ILE B 2 213 ? 10.491  -25.392 -6.094  1   27.34  ? 209 ILE A CD1 1 
ATOM   3813 N N   . ASP B 2 214 ? 10.873  -27.284 -1.174  1   32.37  ? 210 ASP A N   1 
ATOM   3814 C CA  . ASP B 2 214 ? 11.024  -28.553 -0.498  1   33.35  ? 210 ASP A CA  1 
ATOM   3815 C C   . ASP B 2 214 ? 9.642   -29.152 -0.267  1   33     ? 210 ASP A C   1 
ATOM   3816 O O   . ASP B 2 214 ? 9.383   -30.307 -0.597  1   34.58  ? 210 ASP A O   1 
ATOM   3817 C CB  . ASP B 2 214 ? 11.814  -28.374 0.778   1   36.86  ? 210 ASP A CB  1 
ATOM   3818 C CG  . ASP B 2 214 ? 12.141  -29.677 1.484   1   39.09  ? 210 ASP A CG  1 
ATOM   3819 O OD1 . ASP B 2 214 ? 12.907  -30.474 0.889   1   39.33  ? 210 ASP A OD1 1 
ATOM   3820 O OD2 . ASP B 2 214 ? 11.597  -29.893 2.6     1   37.53  ? 210 ASP A OD2 1 
ATOM   3821 N N   . GLN B 2 215 ? 8.744   -28.332 0.277   1   32.99  ? 211 GLN A N   1 
ATOM   3822 C CA  . GLN B 2 215 ? 7.349   -28.695 0.458   1   31.09  ? 211 GLN A CA  1 
ATOM   3823 C C   . GLN B 2 215 ? 6.816   -29.309 -0.835  1   31.79  ? 211 GLN A C   1 
ATOM   3824 O O   . GLN B 2 215 ? 6.361   -30.448 -0.841  1   32.07  ? 211 GLN A O   1 
ATOM   3825 C CB  . GLN B 2 215 ? 6.588   -27.435 0.862   1   30.68  ? 211 GLN A CB  1 
ATOM   3826 C CG  . GLN B 2 215 ? 5.173   -27.682 1.361   1   31.24  ? 211 GLN A CG  1 
ATOM   3827 C CD  . GLN B 2 215 ? 5.134   -28.591 2.566   1   33.48  ? 211 GLN A CD  1 
ATOM   3828 O OE1 . GLN B 2 215 ? 6.006   -28.543 3.444   1   34.42  ? 211 GLN A OE1 1 
ATOM   3829 N NE2 . GLN B 2 215 ? 4.128   -29.455 2.592   1   33.87  ? 211 GLN A NE2 1 
ATOM   3830 N N   . LEU B 2 216 ? 6.921   -28.559 -1.94   1   32.75  ? 212 LEU A N   1 
ATOM   3831 C CA  . LEU B 2 216 ? 6.35    -28.941 -3.225  1   31.76  ? 212 LEU A CA  1 
ATOM   3832 C C   . LEU B 2 216 ? 6.909   -30.294 -3.662  1   31.6   ? 212 LEU A C   1 
ATOM   3833 O O   . LEU B 2 216 ? 6.149   -31.15  -4.115  1   31.72  ? 212 LEU A O   1 
ATOM   3834 C CB  . LEU B 2 216 ? 6.731   -27.844 -4.213  1   35.52  ? 212 LEU A CB  1 
ATOM   3835 C CG  . LEU B 2 216 ? 6.303   -28.05  -5.668  1   38.96  ? 212 LEU A CG  1 
ATOM   3836 C CD1 . LEU B 2 216 ? 4.773   -28.091 -5.764  1   41.78  ? 212 LEU A CD1 1 
ATOM   3837 C CD2 . LEU B 2 216 ? 6.813   -26.909 -6.495  1   39.41  ? 212 LEU A CD2 1 
ATOM   3838 N N   . PHE B 2 217 ? 8.23    -30.482 -3.503  1   29.48  ? 213 PHE A N   1 
ATOM   3839 C CA  . PHE B 2 217 ? 8.895   -31.719 -3.867  1   28.78  ? 213 PHE A CA  1 
ATOM   3840 C C   . PHE B 2 217 ? 8.486   -32.857 -2.931  1   29.16  ? 213 PHE A C   1 
ATOM   3841 O O   . PHE B 2 217 ? 8.434   -34.005 -3.347  1   30.73  ? 213 PHE A O   1 
ATOM   3842 C CB  . PHE B 2 217 ? 10.413  -31.583 -3.852  1   28.45  ? 213 PHE A CB  1 
ATOM   3843 C CG  . PHE B 2 217 ? 11.029  -30.811 -5.006  1   29.51  ? 213 PHE A CG  1 
ATOM   3844 C CD1 . PHE B 2 217 ? 10.246  -30.149 -5.949  1   29.64  ? 213 PHE A CD1 1 
ATOM   3845 C CD2 . PHE B 2 217 ? 12.41   -30.726 -5.137  1   31.15  ? 213 PHE A CD2 1 
ATOM   3846 C CE1 . PHE B 2 217 ? 10.826  -29.407 -6.974  1   28.31  ? 213 PHE A CE1 1 
ATOM   3847 C CE2 . PHE B 2 217 ? 12.985  -30.015 -6.179  1   31.18  ? 213 PHE A CE2 1 
ATOM   3848 C CZ  . PHE B 2 217 ? 12.186  -29.356 -7.085  1   29.37  ? 213 PHE A CZ  1 
ATOM   3849 N N   . ARG B 2 218 ? 8.18    -32.57  -1.668  1   26.81  ? 214 ARG A N   1 
ATOM   3850 C CA  . ARG B 2 218 ? 7.757   -33.666 -0.813  1   26.95  ? 214 ARG A CA  1 
ATOM   3851 C C   . ARG B 2 218 ? 6.426   -34.206 -1.315  1   25.5   ? 214 ARG A C   1 
ATOM   3852 O O   . ARG B 2 218 ? 6.225   -35.416 -1.383  1   26.44  ? 214 ARG A O   1 
ATOM   3853 C CB  . ARG B 2 218 ? 7.711   -33.289 0.677   1   27.17  ? 214 ARG A CB  1 
ATOM   3854 C CG  . ARG B 2 218 ? 9.011   -33.516 1.437   1   27.09  ? 214 ARG A CG  1 
ATOM   3855 C CD  . ARG B 2 218 ? 9.274   -32.367 2.374   1   27.51  ? 214 ARG A CD  1 
ATOM   3856 N NE  . ARG B 2 218 ? 10.543  -32.482 3.101   1   28.37  ? 214 ARG A NE  1 
ATOM   3857 C CZ  . ARG B 2 218 ? 10.753  -33.368 4.047   1   27.83  ? 214 ARG A CZ  1 
ATOM   3858 N NH1 . ARG B 2 218 ? 9.863   -34.326 4.24    1   27.33  ? 214 ARG A NH1 1 
ATOM   3859 N NH2 . ARG B 2 218 ? 11.85   -33.295 4.761   1   28.41  ? 214 ARG A NH2 1 
ATOM   3860 N N   . ILE B 2 219 ? 5.516   -33.283 -1.615  1   23.85  ? 215 ILE A N   1 
ATOM   3861 C CA  . ILE B 2 219 ? 4.224   -33.614 -2.172  1   23.4   ? 215 ILE A CA  1 
ATOM   3862 C C   . ILE B 2 219 ? 4.452   -34.439 -3.437  1   25.96  ? 215 ILE A C   1 
ATOM   3863 O O   . ILE B 2 219 ? 3.978   -35.568 -3.559  1   26.99  ? 215 ILE A O   1 
ATOM   3864 C CB  . ILE B 2 219 ? 3.477   -32.309 -2.452  1   22.61  ? 215 ILE A CB  1 
ATOM   3865 C CG1 . ILE B 2 219 ? 3.039   -31.622 -1.141  1   24.4   ? 215 ILE A CG1 1 
ATOM   3866 C CG2 . ILE B 2 219 ? 2.298   -32.584 -3.357  1   22.33  ? 215 ILE A CG2 1 
ATOM   3867 C CD1 . ILE B 2 219 ? 2.47    -30.212 -1.305  1   23.47  ? 215 ILE A CD1 1 
ATOM   3868 N N   . PHE B 2 220 ? 5.274   -33.894 -4.337  1   27.28  ? 216 PHE A N   1 
ATOM   3869 C CA  . PHE B 2 220 ? 5.603   -34.601 -5.599  1   27.1   ? 216 PHE A CA  1 
ATOM   3870 C C   . PHE B 2 220 ? 6.155   -35.983 -5.318  1   27.9   ? 216 PHE A C   1 
ATOM   3871 O O   . PHE B 2 220 ? 6.001   -36.879 -6.165  1   28.77  ? 216 PHE A O   1 
ATOM   3872 C CB  . PHE B 2 220 ? 6.746   -33.842 -6.265  1   27.06  ? 216 PHE A CB  1 
ATOM   3873 C CG  . PHE B 2 220 ? 6.388   -32.633 -7.113  1   25.61  ? 216 PHE A CG  1 
ATOM   3874 C CD1 . PHE B 2 220 ? 5.112   -32.088 -7.084  1   24.29  ? 216 PHE A CD1 1 
ATOM   3875 C CD2 . PHE B 2 220 ? 7.341   -32.043 -7.932  1   25.32  ? 216 PHE A CD2 1 
ATOM   3876 C CE1 . PHE B 2 220 ? 4.808   -30.982 -7.856  1   23.95  ? 216 PHE A CE1 1 
ATOM   3877 C CE2 . PHE B 2 220 ? 7.028   -30.941 -8.705  1   24.99  ? 216 PHE A CE2 1 
ATOM   3878 C CZ  . PHE B 2 220 ? 5.759   -30.421 -8.676  1   24.42  ? 216 PHE A CZ  1 
ATOM   3879 N N   . ARG B 2 221 ? 6.828   -36.162 -4.18   1   27.93  ? 217 ARG A N   1 
ATOM   3880 C CA  . ARG B 2 221 ? 7.485   -37.469 -3.916  1   29.05  ? 217 ARG A CA  1 
ATOM   3881 C C   . ARG B 2 221 ? 6.49    -38.441 -3.261  1   30.83  ? 217 ARG A C   1 
ATOM   3882 O O   . ARG B 2 221 ? 6.851   -39.625 -3.082  1   33.05  ? 217 ARG A O   1 
ATOM   3883 C CB  . ARG B 2 221 ? 8.734   -37.277 -3.049  1   29.86  ? 217 ARG A CB  1 
ATOM   3884 C CG  . ARG B 2 221 ? 10.005  -37.535 -3.844  1   31.46  ? 217 ARG A CG  1 
ATOM   3885 C CD  . ARG B 2 221 ? 11.181  -36.733 -3.321  1   34.87  ? 217 ARG A CD  1 
ATOM   3886 N NE  . ARG B 2 221 ? 10.844  -35.321 -3.119  1   37.77  ? 217 ARG A NE  1 
ATOM   3887 C CZ  . ARG B 2 221 ? 11.632  -34.454 -2.498  1   38.21  ? 217 ARG A CZ  1 
ATOM   3888 N NH1 . ARG B 2 221 ? 11.309  -34.009 -1.297  1   39.17  ? 217 ARG A NH1 1 
ATOM   3889 N NH2 . ARG B 2 221 ? 12.738  -34.034 -3.084  1   37.79  ? 217 ARG A NH2 1 
ATOM   3890 N N   . THR B 2 222 ? 5.29    -37.962 -2.925  1   31.04  ? 218 THR A N   1 
ATOM   3891 C CA  . THR B 2 222 ? 4.281   -38.824 -2.275  1   30.77  ? 218 THR A CA  1 
ATOM   3892 C C   . THR B 2 222 ? 3.136   -39.051 -3.235  1   32.16  ? 218 THR A C   1 
ATOM   3893 O O   . THR B 2 222 ? 2.611   -40.186 -3.269  1   41.96  ? 218 THR A O   1 
ATOM   3894 C CB  . THR B 2 222 ? 3.803   -38.165 -0.982  1   30.93  ? 218 THR A CB  1 
ATOM   3895 O OG1 . THR B 2 222 ? 4.927   -37.472 -0.448  1   32.51  ? 218 THR A OG1 1 
ATOM   3896 C CG2 . THR B 2 222 ? 3.306   -39.174 0.036   1   32.79  ? 218 THR A CG2 1 
ATOM   3897 N N   . LEU B 2 223 ? 2.76    -38.021 -3.996  1   29.29  ? 219 LEU A N   1 
ATOM   3898 C CA  . LEU B 2 223 ? 1.617   -38.131 -4.896  1   28.36  ? 219 LEU A CA  1 
ATOM   3899 C C   . LEU B 2 223 ? 2.029   -38.171 -6.371  1   26.79  ? 219 LEU A C   1 
ATOM   3900 O O   . LEU B 2 223 ? 1.18    -38.26  -7.241  1   26.44  ? 219 LEU A O   1 
ATOM   3901 C CB  . LEU B 2 223 ? 0.723   -36.918 -4.645  1   29.56  ? 219 LEU A CB  1 
ATOM   3902 C CG  . LEU B 2 223 ? 0.221   -36.713 -3.213  1   30.23  ? 219 LEU A CG  1 
ATOM   3903 C CD1 . LEU B 2 223 ? -0.714  -35.502 -3.212  1   31.82  ? 219 LEU A CD1 1 
ATOM   3904 C CD2 . LEU B 2 223 ? -0.498  -37.956 -2.713  1   30.61  ? 219 LEU A CD2 1 
ATOM   3905 N N   . GLY B 2 224 ? 3.319   -37.992 -6.647  1   26.79  ? 220 GLY A N   1 
ATOM   3906 C CA  . GLY B 2 224 ? 3.847   -37.979 -8.005  1   27.8   ? 220 GLY A CA  1 
ATOM   3907 C C   . GLY B 2 224 ? 3.866   -36.553 -8.562  1   26.92  ? 220 GLY A C   1 
ATOM   3908 O O   . GLY B 2 224 ? 2.986   -35.76  -8.219  1   26.11  ? 220 GLY A O   1 
ATOM   3909 N N   . THR B 2 225 ? 4.862   -36.235 -9.415  1   26.11  ? 221 THR A N   1 
ATOM   3910 C CA  . THR B 2 225 ? 4.908   -34.904 -10.007 1   25.98  ? 221 THR A CA  1 
ATOM   3911 C C   . THR B 2 225 ? 3.722   -34.784 -10.943 1   27.26  ? 221 THR A C   1 
ATOM   3912 O O   . THR B 2 225 ? 3.597   -35.595 -11.853 1   30.43  ? 221 THR A O   1 
ATOM   3913 C CB  . THR B 2 225 ? 6.182   -34.595 -10.8   1   26.47  ? 221 THR A CB  1 
ATOM   3914 O OG1 . THR B 2 225 ? 7.396   -34.894 -10.105 1   27.57  ? 221 THR A OG1 1 
ATOM   3915 C CG2 . THR B 2 225 ? 6.207   -33.154 -11.274 1   24.96  ? 221 THR A CG2 1 
ATOM   3916 N N   . PRO B 2 226 ? 2.863   -33.756 -10.804 1   27.41  ? 222 PRO A N   1 
ATOM   3917 C CA  . PRO B 2 226 ? 1.701   -33.586 -11.677 1   28.49  ? 222 PRO A CA  1 
ATOM   3918 C C   . PRO B 2 226 ? 2.007   -33.082 -13.088 1   31.25  ? 222 PRO A C   1 
ATOM   3919 O O   . PRO B 2 226 ? 3.024   -32.435 -13.358 1   31.08  ? 222 PRO A O   1 
ATOM   3920 C CB  . PRO B 2 226 ? 0.877   -32.565 -10.896 1   27.79  ? 222 PRO A CB  1 
ATOM   3921 C CG  . PRO B 2 226 ? 1.911   -31.673 -10.249 1   26.72  ? 222 PRO A CG  1 
ATOM   3922 C CD  . PRO B 2 226 ? 2.99    -32.668 -9.829  1   27.13  ? 222 PRO A CD  1 
ATOM   3923 N N   . ASP B 2 227 ? 1.087   -33.413 -13.994 1   34.66  ? 223 ASP A N   1 
ATOM   3924 C CA  . ASP B 2 227 ? 1.214   -33.092 -15.403 1   39.36  ? 223 ASP A CA  1 
ATOM   3925 C C   . ASP B 2 227 ? -0.131  -32.578 -15.915 1   40.98  ? 223 ASP A C   1 
ATOM   3926 O O   . ASP B 2 227 ? -1.11   -32.45  -15.16  1   37.96  ? 223 ASP A O   1 
ATOM   3927 C CB  . ASP B 2 227 ? 1.75    -34.262 -16.212 1   39.83  ? 223 ASP A CB  1 
ATOM   3928 C CG  . ASP B 2 227 ? 0.844   -35.479 -16.234 1   42.97  ? 223 ASP A CG  1 
ATOM   3929 O OD1 . ASP B 2 227 ? -0.283  -35.408 -15.669 1   41.93  ? 223 ASP A OD1 1 
ATOM   3930 O OD2 . ASP B 2 227 ? 1.262   -36.474 -16.851 1   47.54  ? 223 ASP A OD2 1 
ATOM   3931 N N   . GLU B 2 228 ? -0.146  -32.293 -17.223 1   40.91  ? 224 GLU A N   1 
ATOM   3932 C CA  . GLU B 2 228 ? -1.321  -31.721 -17.841 1   40.1   ? 224 GLU A CA  1 
ATOM   3933 C C   . GLU B 2 228 ? -2.483  -32.713 -17.771 1   41.44  ? 224 GLU A C   1 
ATOM   3934 O O   . GLU B 2 228 ? -3.644  -32.303 -17.813 1   41.93  ? 224 GLU A O   1 
ATOM   3935 C CB  . GLU B 2 228 ? -0.91   -31.272 -19.24  1   41     ? 224 GLU A CB  1 
ATOM   3936 C CG  . GLU B 2 228 ? -0.193  -29.93  -19.235 1   40.65  ? 224 GLU A CG  1 
ATOM   3937 C CD  . GLU B 2 228 ? -1.065  -28.789 -18.738 1   41.97  ? 224 GLU A CD  1 
ATOM   3938 O OE1 . GLU B 2 228 ? -2.306  -28.875 -18.888 1   42.4   ? 224 GLU A OE1 1 
ATOM   3939 O OE2 . GLU B 2 228 ? -0.509  -27.813 -18.167 1   41.92  ? 224 GLU A OE2 1 
ATOM   3940 N N   . VAL B 2 229 ? -2.18   -34.012 -17.639 1   41.85  ? 225 VAL A N   1 
ATOM   3941 C CA  . VAL B 2 229 ? -3.23   -35.017 -17.664 1   41.11  ? 225 VAL A CA  1 
ATOM   3942 C C   . VAL B 2 229 ? -3.989  -34.953 -16.345 1   39.96  ? 225 VAL A C   1 
ATOM   3943 O O   . VAL B 2 229 ? -5.182  -34.677 -16.333 1   42.02  ? 225 VAL A O   1 
ATOM   3944 C CB  . VAL B 2 229 ? -2.765  -36.449 -17.979 1   42.33  ? 225 VAL A CB  1 
ATOM   3945 C CG1 . VAL B 2 229 ? -3.978  -37.351 -18.182 1   42.48  ? 225 VAL A CG1 1 
ATOM   3946 C CG2 . VAL B 2 229 ? -1.836  -36.509 -19.194 1   42.72  ? 225 VAL A CG2 1 
ATOM   3947 N N   . VAL B 2 230 ? -3.283  -35.155 -15.232 1   38.39  ? 226 VAL A N   1 
ATOM   3948 C CA  . VAL B 2 230 ? -3.948  -35.209 -13.943 1   36.49  ? 226 VAL A CA  1 
ATOM   3949 C C   . VAL B 2 230 ? -4.39   -33.813 -13.515 1   37.21  ? 226 VAL A C   1 
ATOM   3950 O O   . VAL B 2 230 ? -5.41   -33.703 -12.849 1   43.38  ? 226 VAL A O   1 
ATOM   3951 C CB  . VAL B 2 230 ? -3.18   -35.955 -12.833 1   33.99  ? 226 VAL A CB  1 
ATOM   3952 C CG1 . VAL B 2 230 ? -1.712  -35.628 -12.867 1   32.84  ? 226 VAL A CG1 1 
ATOM   3953 C CG2 . VAL B 2 230 ? -3.724  -35.669 -11.437 1   33.88  ? 226 VAL A CG2 1 
ATOM   3954 N N   . TRP B 2 231 ? -3.651  -32.753 -13.867 1   36.02  ? 227 TRP A N   1 
ATOM   3955 C CA  . TRP B 2 231 ? -4.052  -31.415 -13.425 1   35.84  ? 227 TRP A CA  1 
ATOM   3956 C C   . TRP B 2 231 ? -3.95   -30.45  -14.594 1   40.06  ? 227 TRP A C   1 
ATOM   3957 O O   . TRP B 2 231 ? -2.921  -29.791 -14.74  1   44.46  ? 227 TRP A O   1 
ATOM   3958 C CB  . TRP B 2 231 ? -3.182  -30.946 -12.247 1   32.99  ? 227 TRP A CB  1 
ATOM   3959 C CG  . TRP B 2 231 ? -3.51   -29.61  -11.626 1   33.5   ? 227 TRP A CG  1 
ATOM   3960 C CD1 . TRP B 2 231 ? -4.515  -28.744 -11.952 1   35.02  ? 227 TRP A CD1 1 
ATOM   3961 C CD2 . TRP B 2 231 ? -2.831  -29     -10.506 1   32.06  ? 227 TRP A CD2 1 
ATOM   3962 N NE1 . TRP B 2 231 ? -4.504  -27.645 -11.132 1   31.05  ? 227 TRP A NE1 1 
ATOM   3963 C CE2 . TRP B 2 231 ? -3.476  -27.77  -10.242 1   30.39  ? 227 TRP A CE2 1 
ATOM   3964 C CE3 . TRP B 2 231 ? -1.745  -29.378 -9.716  1   33.43  ? 227 TRP A CE3 1 
ATOM   3965 C CZ2 . TRP B 2 231 ? -3.08   -26.916 -9.221  1   30.35  ? 227 TRP A CZ2 1 
ATOM   3966 C CZ3 . TRP B 2 231 ? -1.349  -28.528 -8.707  1   34.58  ? 227 TRP A CZ3 1 
ATOM   3967 C CH2 . TRP B 2 231 ? -2.009  -27.319 -8.461  1   32.82  ? 227 TRP A CH2 1 
ATOM   3968 N N   . PRO B 2 232 ? -4.962  -30.375 -15.499 1   43.09  ? 228 PRO A N   1 
ATOM   3969 C CA  . PRO B 2 232 ? -4.86   -29.501 -16.672 1   42.21  ? 228 PRO A CA  1 
ATOM   3970 C C   . PRO B 2 232 ? -4.523  -28.091 -16.186 1   42.62  ? 228 PRO A C   1 
ATOM   3971 O O   . PRO B 2 232 ? -5.056  -27.641 -15.158 1   40.99  ? 228 PRO A O   1 
ATOM   3972 C CB  . PRO B 2 232 ? -6.248  -29.641 -17.332 1   40.81  ? 228 PRO A CB  1 
ATOM   3973 C CG  . PRO B 2 232 ? -6.699  -31.025 -16.934 1   39.38  ? 228 PRO A CG  1 
ATOM   3974 C CD  . PRO B 2 232 ? -6.217  -31.156 -15.489 1   41.77  ? 228 PRO A CD  1 
ATOM   3975 N N   . GLY B 2 233 ? -3.564  -27.456 -16.879 1   42.09  ? 229 GLY A N   1 
ATOM   3976 C CA  . GLY B 2 233 ? -3.206  -26.063 -16.641 1   44.55  ? 229 GLY A CA  1 
ATOM   3977 C C   . GLY B 2 233 ? -2.024  -25.862 -15.689 1   44.72  ? 229 GLY A C   1 
ATOM   3978 O O   . GLY B 2 233 ? -1.529  -24.742 -15.565 1   46.44  ? 229 GLY A O   1 
ATOM   3979 N N   . VAL B 2 234 ? -1.583  -26.935 -15.018 1   42.2   ? 230 VAL A N   1 
ATOM   3980 C CA  . VAL B 2 234 ? -0.503  -26.851 -14.05  1   39.16  ? 230 VAL A CA  1 
ATOM   3981 C C   . VAL B 2 234 ? 0.76    -26.301 -14.717 1   40.92  ? 230 VAL A C   1 
ATOM   3982 O O   . VAL B 2 234 ? 1.347   -25.353 -14.211 1   40.56  ? 230 VAL A O   1 
ATOM   3983 C CB  . VAL B 2 234 ? -0.22   -28.2   -13.366 1   36.9   ? 230 VAL A CB  1 
ATOM   3984 C CG1 . VAL B 2 234 ? 0.278   -29.239 -14.372 1   34.71  ? 230 VAL A CG1 1 
ATOM   3985 C CG2 . VAL B 2 234 ? 0.739   -28.035 -12.188 1   33.16  ? 230 VAL A CG2 1 
ATOM   3986 N N   . THR B 2 235 ? 1.178   -26.888 -15.846 1   41.76  ? 231 THR A N   1 
ATOM   3987 C CA  . THR B 2 235 ? 2.483   -26.559 -16.409 1   43.42  ? 231 THR A CA  1 
ATOM   3988 C C   . THR B 2 235 ? 2.537   -25.079 -16.815 1   45.03  ? 231 THR A C   1 
ATOM   3989 O O   . THR B 2 235 ? 3.605   -24.575 -17.145 1   48.1   ? 231 THR A O   1 
ATOM   3990 C CB  . THR B 2 235 ? 2.917   -27.488 -17.554 1   43.4   ? 231 THR A CB  1 
ATOM   3991 O OG1 . THR B 2 235 ? 1.872   -27.493 -18.52  1   44.58  ? 231 THR A OG1 1 
ATOM   3992 C CG2 . THR B 2 235 ? 3.245   -28.914 -17.142 1   39.84  ? 231 THR A CG2 1 
ATOM   3993 N N   . SER B 2 236 ? 1.45    -24.361 -16.691 1   44.94  ? 232 SER A N   1 
ATOM   3994 C CA  . SER B 2 236 ? 1.441   -22.946 -17.118 1   46.81  ? 232 SER A CA  1 
ATOM   3995 C C   . SER B 2 236 ? 1.379   -22.051 -15.887 1   47.52  ? 232 SER A C   1 
ATOM   3996 O O   . SER B 2 236 ? 1.374   -20.826 -16.064 1   55.23  ? 232 SER A O   1 
ATOM   3997 C CB  . SER B 2 236 ? 0.285   -22.671 -18.018 1   50.03  ? 232 SER A CB  1 
ATOM   3998 O OG  . SER B 2 236 ? 0.254   -23.593 -19.097 1   60.09  ? 232 SER A OG  1 
ATOM   3999 N N   . MET B 2 237 ? 1.319   -22.646 -14.697 1   41.33  ? 233 MET A N   1 
ATOM   4000 C CA  . MET B 2 237 ? 1.171   -21.837 -13.502 1   37.17  ? 233 MET A CA  1 
ATOM   4001 C C   . MET B 2 237 ? 2.409   -20.993 -13.201 1   37.62  ? 233 MET A C   1 
ATOM   4002 O O   . MET B 2 237 ? 3.54    -21.359 -13.545 1   38.43  ? 233 MET A O   1 
ATOM   4003 C CB  . MET B 2 237 ? 0.797   -22.727 -12.324 1   38.64  ? 233 MET A CB  1 
ATOM   4004 C CG  . MET B 2 237 ? -0.685  -22.937 -12.296 1   45.76  ? 233 MET A CG  1 
ATOM   4005 S SD  . MET B 2 237 ? -1.276  -24.582 -11.859 1   47.43  ? 233 MET A SD  1 
ATOM   4006 C CE  . MET B 2 237 ? -1.065  -24.468 -10.082 1   52.71  ? 233 MET A CE  1 
ATOM   4007 N N   . PRO B 2 238 ? 2.225   -19.83  -12.532 1   37.33  ? 234 PRO A N   1 
ATOM   4008 C CA  . PRO B 2 238 ? 3.278   -18.829 -12.405 1   37.7   ? 234 PRO A CA  1 
ATOM   4009 C C   . PRO B 2 238 ? 4.596   -19.386 -11.885 1   38.88  ? 234 PRO A C   1 
ATOM   4010 O O   . PRO B 2 238 ? 5.654   -19.057 -12.43  1   46.43  ? 234 PRO A O   1 
ATOM   4011 C CB  . PRO B 2 238 ? 2.66    -17.794 -11.456 1   36.92  ? 234 PRO A CB  1 
ATOM   4012 C CG  . PRO B 2 238 ? 1.179   -17.884 -11.699 1   35.22  ? 234 PRO A CG  1 
ATOM   4013 C CD  . PRO B 2 238 ? 0.972   -19.381 -11.895 1   36.76  ? 234 PRO A CD  1 
ATOM   4014 N N   . ASP B 2 239 ? 4.528   -20.231 -10.848 1   35.62  ? 235 ASP A N   1 
ATOM   4015 C CA  . ASP B 2 239 ? 5.74    -20.749 -10.232 1   36.73  ? 235 ASP A CA  1 
ATOM   4016 C C   . ASP B 2 239 ? 5.972   -22.205 -10.618 1   37.4   ? 235 ASP A C   1 
ATOM   4017 O O   . ASP B 2 239 ? 6.842   -22.847 -10.044 1   38.84  ? 235 ASP A O   1 
ATOM   4018 C CB  . ASP B 2 239 ? 5.78    -20.528 -8.726  1   34.92  ? 235 ASP A CB  1 
ATOM   4019 C CG  . ASP B 2 239 ? 5.62    -19.081 -8.295  1   35.77  ? 235 ASP A CG  1 
ATOM   4020 O OD1 . ASP B 2 239 ? 6.207   -18.22  -8.963  1   36.37  ? 235 ASP A OD1 1 
ATOM   4021 O OD2 . ASP B 2 239 ? 4.912   -18.825 -7.295  1   36.41  ? 235 ASP A OD2 1 
ATOM   4022 N N   . TYR B 2 240 ? 5.22    -22.71  -11.597 1   38.31  ? 236 TYR A N   1 
ATOM   4023 C CA  . TYR B 2 240 ? 5.575   -23.974 -12.208 1   40.84  ? 236 TYR A CA  1 
ATOM   4024 C C   . TYR B 2 240 ? 6.863   -23.744 -12.996 1   45.43  ? 236 TYR A C   1 
ATOM   4025 O O   . TYR B 2 240 ? 7.015   -22.69  -13.625 1   49.16  ? 236 TYR A O   1 
ATOM   4026 C CB  . TYR B 2 240 ? 4.487   -24.552 -13.119 1   40.91  ? 236 TYR A CB  1 
ATOM   4027 C CG  . TYR B 2 240 ? 4.937   -25.885 -13.691 1   43.33  ? 236 TYR A CG  1 
ATOM   4028 C CD1 . TYR B 2 240 ? 4.966   -27.02  -12.891 1   43.06  ? 236 TYR A CD1 1 
ATOM   4029 C CD2 . TYR B 2 240 ? 5.399   -25.991 -14.995 1   46.03  ? 236 TYR A CD2 1 
ATOM   4030 C CE1 . TYR B 2 240 ? 5.401   -28.236 -13.378 1   43.19  ? 236 TYR A CE1 1 
ATOM   4031 C CE2 . TYR B 2 240 ? 5.833   -27.206 -15.502 1   47.44  ? 236 TYR A CE2 1 
ATOM   4032 C CZ  . TYR B 2 240 ? 5.847   -28.325 -14.684 1   46.46  ? 236 TYR A CZ  1 
ATOM   4033 O OH  . TYR B 2 240 ? 6.298   -29.522 -15.157 1   48.96  ? 236 TYR A OH  1 
ATOM   4034 N N   . LYS B 2 241 ? 7.774   -24.725 -12.923 1   41.69  ? 237 LYS A N   1 
ATOM   4035 C CA  . LYS B 2 241 ? 9.047   -24.708 -13.62  1   40.79  ? 237 LYS A CA  1 
ATOM   4036 C C   . LYS B 2 241 ? 9.254   -26.054 -14.319 1   37.92  ? 237 LYS A C   1 
ATOM   4037 O O   . LYS B 2 241 ? 9.252   -27.104 -13.68  1   35.6   ? 237 LYS A O   1 
ATOM   4038 C CB  . LYS B 2 241 ? 10.174  -24.5   -12.596 1   42.78  ? 237 LYS A CB  1 
ATOM   4039 C CG  . LYS B 2 241 ? 10.772  -23.123 -12.457 1   47.17  ? 237 LYS A CG  1 
ATOM   4040 C CD  . LYS B 2 241 ? 9.951   -22.025 -11.789 1   48.59  ? 237 LYS A CD  1 
ATOM   4041 C CE  . LYS B 2 241 ? 10.457  -20.621 -12.059 1   48.57  ? 237 LYS A CE  1 
ATOM   4042 N NZ  . LYS B 2 241 ? 9.332   -19.679 -11.963 1   48.29  ? 237 LYS A NZ  1 
ATOM   4043 N N   . PRO B 2 242 ? 9.497   -26.087 -15.649 1   36.77  ? 238 PRO A N   1 
ATOM   4044 C CA  . PRO B 2 242 ? 9.699   -27.348 -16.374 1   36.67  ? 238 PRO A CA  1 
ATOM   4045 C C   . PRO B 2 242 ? 10.853  -28.238 -15.897 1   36.6   ? 238 PRO A C   1 
ATOM   4046 O O   . PRO B 2 242 ? 10.978  -29.404 -16.29  1   34.64  ? 238 PRO A O   1 
ATOM   4047 C CB  . PRO B 2 242 ? 9.937   -26.81  -17.783 1   36.54  ? 238 PRO A CB  1 
ATOM   4048 C CG  . PRO B 2 242 ? 10.618  -25.496 -17.529 1   37.17  ? 238 PRO A CG  1 
ATOM   4049 C CD  . PRO B 2 242 ? 9.65    -24.917 -16.517 1   36.88  ? 238 PRO A CD  1 
ATOM   4050 N N   . SER B 2 243 ? 11.716  -27.649 -15.065 1   37.99  ? 239 SER A N   1 
ATOM   4051 C CA  . SER B 2 243 ? 12.918  -28.3   -14.567 1   38.78  ? 239 SER A CA  1 
ATOM   4052 C C   . SER B 2 243 ? 12.545  -29.289 -13.455 1   35.82  ? 239 SER A C   1 
ATOM   4053 O O   . SER B 2 243 ? 13.359  -30.126 -13.058 1   36.7   ? 239 SER A O   1 
ATOM   4054 C CB  . SER B 2 243 ? 13.888  -27.256 -14.061 1   41.39  ? 239 SER A CB  1 
ATOM   4055 O OG  . SER B 2 243 ? 13.369  -26.683 -12.858 1   44.64  ? 239 SER A OG  1 
ATOM   4056 N N   . PHE B 2 244 ? 11.323  -29.159 -12.931 1   32.39  ? 240 PHE A N   1 
ATOM   4057 C CA  . PHE B 2 244 ? 10.862  -29.964 -11.81  1   30.12  ? 240 PHE A CA  1 
ATOM   4058 C C   . PHE B 2 244 ? 11.056  -31.436 -12.119 1   30.62  ? 240 PHE A C   1 
ATOM   4059 O O   . PHE B 2 244 ? 10.574  -31.952 -13.13  1   31.48  ? 240 PHE A O   1 
ATOM   4060 C CB  . PHE B 2 244 ? 9.365   -29.834 -11.535 1   27.79  ? 240 PHE A CB  1 
ATOM   4061 C CG  . PHE B 2 244 ? 8.941   -28.551 -10.841 1   27.01  ? 240 PHE A CG  1 
ATOM   4062 C CD1 . PHE B 2 244 ? 9.871   -27.671 -10.298 1   26.76  ? 240 PHE A CD1 1 
ATOM   4063 C CD2 . PHE B 2 244 ? 7.598   -28.237 -10.711 1   26.39  ? 240 PHE A CD2 1 
ATOM   4064 C CE1 . PHE B 2 244 ? 9.468   -26.506 -9.669  1   25.46  ? 240 PHE A CE1 1 
ATOM   4065 C CE2 . PHE B 2 244 ? 7.213   -27.084 -10.055 1   25.6   ? 240 PHE A CE2 1 
ATOM   4066 C CZ  . PHE B 2 244 ? 8.15    -26.22  -9.552  1   25.12  ? 240 PHE A CZ  1 
ATOM   4067 N N   . PRO B 2 245 ? 11.737  -32.162 -11.218 1   30.43  ? 241 PRO A N   1 
ATOM   4068 C CA  . PRO B 2 245 ? 11.916  -33.6   -11.411 1   31.9   ? 241 PRO A CA  1 
ATOM   4069 C C   . PRO B 2 245 ? 10.543  -34.26  -11.544 1   32.28  ? 241 PRO A C   1 
ATOM   4070 O O   . PRO B 2 245 ? 9.6     -33.895 -10.845 1   30.42  ? 241 PRO A O   1 
ATOM   4071 C CB  . PRO B 2 245 ? 12.686  -34.009 -10.149 1   32.19  ? 241 PRO A CB  1 
ATOM   4072 C CG  . PRO B 2 245 ? 13.33   -32.703 -9.678  1   31.54  ? 241 PRO A CG  1 
ATOM   4073 C CD  . PRO B 2 245 ? 12.316  -31.634 -9.978  1   29.34  ? 241 PRO A CD  1 
ATOM   4074 N N   . LYS B 2 246 ? 10.407  -35.196 -12.494 1   35.96  ? 242 LYS A N   1 
ATOM   4075 C CA  . LYS B 2 246 ? 9.12    -35.858 -12.705 1   36.04  ? 242 LYS A CA  1 
ATOM   4076 C C   . LYS B 2 246 ? 9.097   -37.168 -11.919 1   35.46  ? 242 LYS A C   1 
ATOM   4077 O O   . LYS B 2 246 ? 9.708   -38.132 -12.366 1   40.89  ? 242 LYS A O   1 
ATOM   4078 C CB  . LYS B 2 246 ? 8.869   -36.053 -14.204 1   35.19  ? 242 LYS A CB  1 
ATOM   4079 C CG  . LYS B 2 246 ? 8.489   -34.783 -14.923 1   37.05  ? 242 LYS A CG  1 
ATOM   4080 C CD  . LYS B 2 246 ? 8.122   -35.008 -16.379 1   44.73  ? 242 LYS A CD  1 
ATOM   4081 C CE  . LYS B 2 246 ? 7.961   -33.761 -17.205 1   49.49  ? 242 LYS A CE  1 
ATOM   4082 N NZ  . LYS B 2 246 ? 9.274   -33.238 -17.597 1   53.36  ? 242 LYS A NZ  1 
ATOM   4083 N N   . TRP B 2 247 ? 8.472   -37.156 -10.736 1   31.37  ? 243 TRP A N   1 
ATOM   4084 C CA  . TRP B 2 247 ? 8.418   -38.334 -9.886  1   31.2   ? 243 TRP A CA  1 
ATOM   4085 C C   . TRP B 2 247 ? 7.129   -39.093 -10.174 1   31.46  ? 243 TRP A C   1 
ATOM   4086 O O   . TRP B 2 247 ? 6.107   -38.482 -10.506 1   30.65  ? 243 TRP A O   1 
ATOM   4087 C CB  . TRP B 2 247 ? 8.455   -37.964 -8.398  1   30.61  ? 243 TRP A CB  1 
ATOM   4088 C CG  . TRP B 2 247 ? 9.776   -37.493 -7.845  1   31.32  ? 243 TRP A CG  1 
ATOM   4089 C CD1 . TRP B 2 247 ? 10.848  -38.259 -7.479  1   31.65  ? 243 TRP A CD1 1 
ATOM   4090 C CD2 . TRP B 2 247 ? 10.13   -36.127 -7.526  1   31.04  ? 243 TRP A CD2 1 
ATOM   4091 N NE1 . TRP B 2 247 ? 11.854  -37.467 -6.99   1   32.36  ? 243 TRP A NE1 1 
ATOM   4092 C CE2 . TRP B 2 247 ? 11.443  -36.153 -7.002  1   31.93  ? 243 TRP A CE2 1 
ATOM   4093 C CE3 . TRP B 2 247 ? 9.477   -34.891 -7.644  1   30.38  ? 243 TRP A CE3 1 
ATOM   4094 C CZ2 . TRP B 2 247 ? 12.105  -34.984 -6.605  1   31.91  ? 243 TRP A CZ2 1 
ATOM   4095 C CZ3 . TRP B 2 247 ? 10.132  -33.747 -7.231  1   30.58  ? 243 TRP A CZ3 1 
ATOM   4096 C CH2 . TRP B 2 247 ? 11.433  -33.787 -6.724  1   30.55  ? 243 TRP A CH2 1 
ATOM   4097 N N   . ALA B 2 248 ? 7.198   -40.416 -9.996  1   31.79  ? 244 ALA A N   1 
ATOM   4098 C CA  . ALA B 2 248 ? 6.084   -41.314 -10.213 1   33.02  ? 244 ALA A CA  1 
ATOM   4099 C C   . ALA B 2 248 ? 5.142   -41.266 -9.015  1   35.59  ? 244 ALA A C   1 
ATOM   4100 O O   . ALA B 2 248 ? 5.58    -41.025 -7.894  1   38.44  ? 244 ALA A O   1 
ATOM   4101 C CB  . ALA B 2 248 ? 6.653   -42.677 -10.412 1   32.46  ? 244 ALA A CB  1 
ATOM   4102 N N   . ARG B 2 249 ? 3.84    -41.481 -9.256  1   38.93  ? 245 ARG A N   1 
ATOM   4103 C CA  . ARG B 2 249 ? 2.874   -41.611 -8.176  1   38.9   ? 245 ARG A CA  1 
ATOM   4104 C C   . ARG B 2 249 ? 3.086   -42.992 -7.561  1   42.21  ? 245 ARG A C   1 
ATOM   4105 O O   . ARG B 2 249 ? 3.138   -43.985 -8.285  1   41     ? 245 ARG A O   1 
ATOM   4106 C CB  . ARG B 2 249 ? 1.456   -41.423 -8.723  1   37.01  ? 245 ARG A CB  1 
ATOM   4107 C CG  . ARG B 2 249 ? 0.382   -41.523 -7.654  1   39.43  ? 245 ARG A CG  1 
ATOM   4108 C CD  . ARG B 2 249 ? -0.945  -41.021 -8.149  1   39.24  ? 245 ARG A CD  1 
ATOM   4109 N NE  . ARG B 2 249 ? -1.895  -41.141 -7.039  1   41.38  ? 245 ARG A NE  1 
ATOM   4110 C CZ  . ARG B 2 249 ? -2.331  -40.149 -6.26   1   39.58  ? 245 ARG A CZ  1 
ATOM   4111 N NH1 . ARG B 2 249 ? -1.752  -38.954 -6.333  1   35.8   ? 245 ARG A NH1 1 
ATOM   4112 N NH2 . ARG B 2 249 ? -3.31   -40.391 -5.388  1   40.83  ? 245 ARG A NH2 1 
ATOM   4113 N N   . GLN B 2 250 ? 3.258   -43.038 -6.236  1   46.84  ? 246 GLN A N   1 
ATOM   4114 C CA  . GLN B 2 250 ? 3.412   -44.329 -5.59   1   51.66  ? 246 GLN A CA  1 
ATOM   4115 C C   . GLN B 2 250 ? 2.009   -44.77  -5.176  1   55.02  ? 246 GLN A C   1 
ATOM   4116 O O   . GLN B 2 250 ? 1.104   -43.928 -5.036  1   53.37  ? 246 GLN A O   1 
ATOM   4117 C CB  . GLN B 2 250 ? 4.391   -44.302 -4.415  1   52.26  ? 246 GLN A CB  1 
ATOM   4118 C CG  . GLN B 2 250 ? 3.772   -43.706 -3.158  1   58.01  ? 246 GLN A CG  1 
ATOM   4119 C CD  . GLN B 2 250 ? 4.787   -43.167 -2.178  1   63.33  ? 246 GLN A CD  1 
ATOM   4120 O OE1 . GLN B 2 250 ? 4.445   -42.424 -1.241  1   61.53  ? 246 GLN A OE1 1 
ATOM   4121 N NE2 . GLN B 2 250 ? 6.048   -43.51  -2.43   1   63.81  ? 246 GLN A NE2 1 
ATOM   4122 N N   . ASP B 2 251 ? 1.863   -46.093 -5.007  1   55.46  ? 247 ASP A N   1 
ATOM   4123 C CA  . ASP B 2 251 ? 0.691   -46.711 -4.409  1   55.74  ? 247 ASP A CA  1 
ATOM   4124 C C   . ASP B 2 251 ? 0.247   -45.864 -3.215  1   50.06  ? 247 ASP A C   1 
ATOM   4125 O O   . ASP B 2 251 ? 0.979   -45.771 -2.229  1   54.57  ? 247 ASP A O   1 
ATOM   4126 C CB  . ASP B 2 251 ? 1.05    -48.107 -3.914  1   63.23  ? 247 ASP A CB  1 
ATOM   4127 C CG  . ASP B 2 251 ? -0.101  -49.089 -3.79   1   71     ? 247 ASP A CG  1 
ATOM   4128 O OD1 . ASP B 2 251 ? -1.212  -48.749 -4.26   1   79.52  ? 247 ASP A OD1 1 
ATOM   4129 O OD2 . ASP B 2 251 ? 0.145   -50.192 -3.255  1   73.39  ? 247 ASP A OD2 1 
ATOM   4130 N N   . PHE B 2 252 ? -0.939  -45.25  -3.309  1   42.71  ? 248 PHE A N   1 
ATOM   4131 C CA  . PHE B 2 252 ? -1.479  -44.428 -2.236  1   37.97  ? 248 PHE A CA  1 
ATOM   4132 C C   . PHE B 2 252 ? -1.681  -45.288 -0.991  1   37.97  ? 248 PHE A C   1 
ATOM   4133 O O   . PHE B 2 252 ? -1.95   -44.793 0.096   1   35.8   ? 248 PHE A O   1 
ATOM   4134 C CB  . PHE B 2 252 ? -2.83   -43.856 -2.673  1   38.1   ? 248 PHE A CB  1 
ATOM   4135 C CG  . PHE B 2 252 ? -3.196  -42.574 -1.942  1   37.8   ? 248 PHE A CG  1 
ATOM   4136 C CD1 . PHE B 2 252 ? -2.68   -41.354 -2.362  1   36.48  ? 248 PHE A CD1 1 
ATOM   4137 C CD2 . PHE B 2 252 ? -4.022  -42.598 -0.83   1   39.01  ? 248 PHE A CD2 1 
ATOM   4138 C CE1 . PHE B 2 252 ? -2.989  -40.187 -1.71   1   36.43  ? 248 PHE A CE1 1 
ATOM   4139 C CE2 . PHE B 2 252 ? -4.335  -41.418 -0.171  1   43.32  ? 248 PHE A CE2 1 
ATOM   4140 C CZ  . PHE B 2 252 ? -3.799  -40.217 -0.597  1   43.02  ? 248 PHE A CZ  1 
ATOM   4141 N N   . SER B 2 253 ? -1.597  -46.609 -1.159  1   40.59  ? 249 SER A N   1 
ATOM   4142 C CA  . SER B 2 253 ? -1.752  -47.455 0.001   1   40.37  ? 249 SER A CA  1 
ATOM   4143 C C   . SER B 2 253 ? -0.482  -47.371 0.847   1   42.67  ? 249 SER A C   1 
ATOM   4144 O O   . SER B 2 253 ? -0.489  -47.734 2.024   1   46.32  ? 249 SER A O   1 
ATOM   4145 C CB  . SER B 2 253 ? -2.116  -48.844 -0.404  1   39.84  ? 249 SER A CB  1 
ATOM   4146 O OG  . SER B 2 253 ? -1.021  -49.406 -1.086  1   41.81  ? 249 SER A OG  1 
ATOM   4147 N N   . LYS B 2 254 ? 0.598   -46.828 0.263   1   43.87  ? 250 LYS A N   1 
ATOM   4148 C CA  . LYS B 2 254 ? 1.872   -46.684 0.957   1   43.34  ? 250 LYS A CA  1 
ATOM   4149 C C   . LYS B 2 254 ? 1.968   -45.325 1.645   1   43.97  ? 250 LYS A C   1 
ATOM   4150 O O   . LYS B 2 254 ? 2.838   -45.124 2.488   1   50.19  ? 250 LYS A O   1 
ATOM   4151 C CB  . LYS B 2 254 ? 3.009   -46.902 -0.031  1   41.47  ? 250 LYS A CB  1 
ATOM   4152 C CG  . LYS B 2 254 ? 3.112   -48.369 -0.423  1   43.89  ? 250 LYS A CG  1 
ATOM   4153 C CD  . LYS B 2 254 ? 3.428   -49.305 0.747   1   42.83  ? 250 LYS A CD  1 
ATOM   4154 C CE  . LYS B 2 254 ? 3.242   -50.724 0.329   1   43.74  ? 250 LYS A CE  1 
ATOM   4155 N NZ  . LYS B 2 254 ? 1.863   -50.937 -0.102  1   42.59  ? 250 LYS A NZ  1 
ATOM   4156 N N   . VAL B 2 255 ? 1.052   -44.413 1.314   1   39.28  ? 251 VAL A N   1 
ATOM   4157 C CA  . VAL B 2 255 ? 1.075   -43.114 1.943   1   34.57  ? 251 VAL A CA  1 
ATOM   4158 C C   . VAL B 2 255 ? 0.61    -43.252 3.381   1   35.75  ? 251 VAL A C   1 
ATOM   4159 O O   . VAL B 2 255 ? 1.223   -42.666 4.257   1   40.82  ? 251 VAL A O   1 
ATOM   4160 C CB  . VAL B 2 255 ? 0.229   -42.094 1.18    1   32.05  ? 251 VAL A CB  1 
ATOM   4161 C CG1 . VAL B 2 255 ? 0.187   -40.766 1.922   1   29.12  ? 251 VAL A CG1 1 
ATOM   4162 C CG2 . VAL B 2 255 ? 0.736   -41.957 -0.251  1   32.15  ? 251 VAL A CG2 1 
ATOM   4163 N N   . VAL B 2 256 ? -0.478  -43.987 3.62    1   34.32  ? 252 VAL A N   1 
ATOM   4164 C CA  . VAL B 2 256 ? -0.937  -44.151 4.986   1   33.24  ? 252 VAL A CA  1 
ATOM   4165 C C   . VAL B 2 256 ? -1.213  -45.634 5.234   1   36.25  ? 252 VAL A C   1 
ATOM   4166 O O   . VAL B 2 256 ? -2.361  -46.057 5.37    1   37.84  ? 252 VAL A O   1 
ATOM   4167 C CB  . VAL B 2 256 ? -2.1    -43.196 5.313   1   31.16  ? 252 VAL A CB  1 
ATOM   4168 C CG1 . VAL B 2 256 ? -2.414  -43.167 6.802   1   32.33  ? 252 VAL A CG1 1 
ATOM   4169 C CG2 . VAL B 2 256 ? -1.779  -41.773 4.888   1   28.96  ? 252 VAL A CG2 1 
ATOM   4170 N N   . PRO B 2 257 ? -0.146  -46.475 5.304   1   36.69  ? 253 PRO A N   1 
ATOM   4171 C CA  . PRO B 2 257 ? -0.282  -47.935 5.322   1   37.49  ? 253 PRO A CA  1 
ATOM   4172 C C   . PRO B 2 257 ? -1.394  -48.559 6.148   1   37.75  ? 253 PRO A C   1 
ATOM   4173 O O   . PRO B 2 257 ? -2.01   -49.501 5.692   1   38.52  ? 253 PRO A O   1 
ATOM   4174 C CB  . PRO B 2 257 ? 1.092   -48.41  5.779   1   38.27  ? 253 PRO A CB  1 
ATOM   4175 C CG  . PRO B 2 257 ? 2.016   -47.363 5.237   1   36.8   ? 253 PRO A CG  1 
ATOM   4176 C CD  . PRO B 2 257 ? 1.261   -46.057 5.355   1   34.83  ? 253 PRO A CD  1 
ATOM   4177 N N   . PRO B 2 258 ? -1.654  -48.111 7.405   1   39.38  ? 254 PRO A N   1 
ATOM   4178 C CA  . PRO B 2 258 ? -2.74   -48.648 8.204   1   41.27  ? 254 PRO A CA  1 
ATOM   4179 C C   . PRO B 2 258 ? -4.136  -48.35  7.681   1   41.89  ? 254 PRO A C   1 
ATOM   4180 O O   . PRO B 2 258 ? -5.044  -49.157 7.92    1   43.38  ? 254 PRO A O   1 
ATOM   4181 C CB  . PRO B 2 258 ? -2.471  -47.965 9.543   1   40.32  ? 254 PRO A CB  1 
ATOM   4182 C CG  . PRO B 2 258 ? -1      -47.745 9.569   1   39.55  ? 254 PRO A CG  1 
ATOM   4183 C CD  . PRO B 2 258 ? -0.911  -47.116 8.216   1   38.86  ? 254 PRO A CD  1 
ATOM   4184 N N   . LEU B 2 259 ? -4.302  -47.237 6.97    1   40.1   ? 255 LEU A N   1 
ATOM   4185 C CA  . LEU B 2 259 ? -5.637  -46.831 6.466   1   41.2   ? 255 LEU A CA  1 
ATOM   4186 C C   . LEU B 2 259 ? -6.183  -47.911 5.527   1   45.6   ? 255 LEU A C   1 
ATOM   4187 O O   . LEU B 2 259 ? -5.39   -48.552 4.826   1   48.36  ? 255 LEU A O   1 
ATOM   4188 C CB  . LEU B 2 259 ? -5.574  -45.469 5.779   1   39.3   ? 255 LEU A CB  1 
ATOM   4189 C CG  . LEU B 2 259 ? -6.725  -44.5   6.048   1   38.99  ? 255 LEU A CG  1 
ATOM   4190 C CD1 . LEU B 2 259 ? -7.189  -44.581 7.486   1   37     ? 255 LEU A CD1 1 
ATOM   4191 C CD2 . LEU B 2 259 ? -6.248  -43.103 5.715   1   36.18  ? 255 LEU A CD2 1 
ATOM   4192 N N   . ASP B 2 260 ? -7.502  -48.058 5.49    1   46.59  ? 256 ASP A N   1 
ATOM   4193 C CA  . ASP B 2 260 ? -8.126  -49.123 4.672   1   47.06  ? 256 ASP A CA  1 
ATOM   4194 C C   . ASP B 2 260 ? -8.756  -48.52  3.423   1   45.39  ? 256 ASP A C   1 
ATOM   4195 O O   . ASP B 2 260 ? -8.604  -47.312 3.213   1   43.78  ? 256 ASP A O   1 
ATOM   4196 C CB  . ASP B 2 260 ? -9.097  -49.946 5.501   1   46.72  ? 256 ASP A CB  1 
ATOM   4197 C CG  . ASP B 2 260 ? -8.446  -50.966 6.424   1   42.69  ? 256 ASP A CG  1 
ATOM   4198 O OD1 . ASP B 2 260 ? -7.251  -51.263 6.221   1   41.81  ? 256 ASP A OD1 1 
ATOM   4199 O OD2 . ASP B 2 260 ? -9.135  -51.448 7.344   1   39.96  ? 256 ASP A OD2 1 
ATOM   4200 N N   . GLU B 2 261 ? -9.459  -49.338 2.654   1   44.42  ? 257 GLU A N   1 
ATOM   4201 C CA  . GLU B 2 261 ? -9.982  -48.886 1.35    1   42.11  ? 257 GLU A CA  1 
ATOM   4202 C C   . GLU B 2 261 ? -10.784 -47.609 1.494   1   40.62  ? 257 GLU A C   1 
ATOM   4203 O O   . GLU B 2 261 ? -10.544 -46.679 0.715   1   37.82  ? 257 GLU A O   1 
ATOM   4204 C CB  . GLU B 2 261 ? -10.852 -49.988 0.757   1   45.48  ? 257 GLU A CB  1 
ATOM   4205 C CG  . GLU B 2 261 ? -10.771 -50.052 -0.763  1   48.55  ? 257 GLU A CG  1 
ATOM   4206 C CD  . GLU B 2 261 ? -11.846 -50.931 -1.363  1   56.46  ? 257 GLU A CD  1 
ATOM   4207 O OE1 . GLU B 2 261 ? -11.756 -51.24  -2.568  1   58.87  ? 257 GLU A OE1 1 
ATOM   4208 O OE2 . GLU B 2 261 ? -12.772 -51.306 -0.617  1   61.57  ? 257 GLU A OE2 1 
ATOM   4209 N N   . ASP B 2 262 ? -11.709 -47.581 2.444   1   40.95  ? 258 ASP A N   1 
ATOM   4210 C CA  . ASP B 2 262 ? -12.568 -46.41  2.498   1   38.37  ? 258 ASP A CA  1 
ATOM   4211 C C   . ASP B 2 262 ? -11.73  -45.207 2.883   1   37.36  ? 258 ASP A C   1 
ATOM   4212 O O   . ASP B 2 262 ? -11.709 -44.214 2.155   1   36.28  ? 258 ASP A O   1 
ATOM   4213 C CB  . ASP B 2 262 ? -13.712 -46.59  3.471   1   40.55  ? 258 ASP A CB  1 
ATOM   4214 C CG  . ASP B 2 262 ? -14.788 -47.56  3.006   1   45.03  ? 258 ASP A CG  1 
ATOM   4215 O OD1 . ASP B 2 262 ? -15.054 -47.571 1.789   1   44.71  ? 258 ASP A OD1 1 
ATOM   4216 O OD2 . ASP B 2 262 ? -15.38  -48.267 3.869   1   48.75  ? 258 ASP A OD2 1 
ATOM   4217 N N   . GLY B 2 263 ? -11.016 -45.323 4.015   1   37.75  ? 259 GLY A N   1 
ATOM   4218 C CA  . GLY B 2 263 ? -10.114 -44.274 4.475   1   34.81  ? 259 GLY A CA  1 
ATOM   4219 C C   . GLY B 2 263 ? -9.249  -43.72  3.344   1   33.18  ? 259 GLY A C   1 
ATOM   4220 O O   . GLY B 2 263 ? -9.242  -42.522 3.113   1   30.31  ? 259 GLY A O   1 
ATOM   4221 N N   . ARG B 2 264 ? -8.538  -44.605 2.633   1   34.71  ? 260 ARG A N   1 
ATOM   4222 C CA  . ARG B 2 264 ? -7.711  -44.206 1.5     1   34.14  ? 260 ARG A CA  1 
ATOM   4223 C C   . ARG B 2 264 ? -8.494  -43.469 0.408   1   33.55  ? 260 ARG A C   1 
ATOM   4224 O O   . ARG B 2 264 ? -7.942  -42.588 -0.243  1   33.54  ? 260 ARG A O   1 
ATOM   4225 C CB  . ARG B 2 264 ? -7.214  -45.427 0.727   1   34.87  ? 260 ARG A CB  1 
ATOM   4226 C CG  . ARG B 2 264 ? -5.948  -46.077 1.241   1   35.96  ? 260 ARG A CG  1 
ATOM   4227 C CD  . ARG B 2 264 ? -5.402  -46.876 0.073   1   37.42  ? 260 ARG A CD  1 
ATOM   4228 N NE  . ARG B 2 264 ? -6.13   -48.149 0.017   1   40.63  ? 260 ARG A NE  1 
ATOM   4229 C CZ  . ARG B 2 264 ? -6.004  -49.15  0.9     1   43.33  ? 260 ARG A CZ  1 
ATOM   4230 N NH1 . ARG B 2 264 ? -5.186  -49.025 1.941   1   43.49  ? 260 ARG A NH1 1 
ATOM   4231 N NH2 . ARG B 2 264 ? -6.67   -50.277 0.699   1   45.74  ? 260 ARG A NH2 1 
ATOM   4232 N N   . SER B 2 265 ? -9.717  -43.94  0.12    1   32.43  ? 261 SER A N   1 
ATOM   4233 C CA  . SER B 2 265 ? -10.529 -43.374 -0.937  1   30.43  ? 261 SER A CA  1 
ATOM   4234 C C   . SER B 2 265 ? -10.738 -41.917 -0.566  1   28.46  ? 261 SER A C   1 
ATOM   4235 O O   . SER B 2 265 ? -10.383 -41.017 -1.32   1   27.43  ? 261 SER A O   1 
ATOM   4236 C CB  . SER B 2 265 ? -11.84  -44.126 -1.083  1   31.84  ? 261 SER A CB  1 
ATOM   4237 O OG  . SER B 2 265 ? -12.813 -43.437 -1.86   1   30.74  ? 261 SER A OG  1 
ATOM   4238 N N   . LEU B 2 266 ? -11.178 -41.729 0.677   1   28.22  ? 262 LEU A N   1 
ATOM   4239 C CA  . LEU B 2 266 ? -11.469 -40.405 1.173   1   27.91  ? 262 LEU A CA  1 
ATOM   4240 C C   . LEU B 2 266 ? -10.196 -39.574 1.055   1   28.96  ? 262 LEU A C   1 
ATOM   4241 O O   . LEU B 2 266 ? -10.227 -38.49  0.456   1   29.71  ? 262 LEU A O   1 
ATOM   4242 C CB  . LEU B 2 266 ? -12.026 -40.467 2.598   1   27.3   ? 262 LEU A CB  1 
ATOM   4243 C CG  . LEU B 2 266 ? -12.351 -39.109 3.237   1   25.46  ? 262 LEU A CG  1 
ATOM   4244 C CD1 . LEU B 2 266 ? -13.107 -38.179 2.291   1   25.24  ? 262 LEU A CD1 1 
ATOM   4245 C CD2 . LEU B 2 266 ? -13.126 -39.256 4.505   1   25.05  ? 262 LEU A CD2 1 
ATOM   4246 N N   . LEU B 2 267 ? -9.086  -40.115 1.592   1   28.39  ? 263 LEU A N   1 
ATOM   4247 C CA  . LEU B 2 267 ? -7.861  -39.351 1.695   1   26.81  ? 263 LEU A CA  1 
ATOM   4248 C C   . LEU B 2 267 ? -7.463  -38.895 0.306   1   27.92  ? 263 LEU A C   1 
ATOM   4249 O O   . LEU B 2 267 ? -7.168  -37.722 0.127   1   30.77  ? 263 LEU A O   1 
ATOM   4250 C CB  . LEU B 2 267 ? -6.732  -40.132 2.35    1   27.85  ? 263 LEU A CB  1 
ATOM   4251 C CG  . LEU B 2 267 ? -5.43   -39.346 2.547   1   26.78  ? 263 LEU A CG  1 
ATOM   4252 C CD1 . LEU B 2 267 ? -5.628  -38.134 3.461   1   24.81  ? 263 LEU A CD1 1 
ATOM   4253 C CD2 . LEU B 2 267 ? -4.325  -40.236 3.079   1   26.52  ? 263 LEU A CD2 1 
ATOM   4254 N N   . SER B 2 268 ? -7.536  -39.806 -0.669  1   29.57  ? 264 SER A N   1 
ATOM   4255 C CA  . SER B 2 268 ? -7.07   -39.558 -2.029  1   30.32  ? 264 SER A CA  1 
ATOM   4256 C C   . SER B 2 268 ? -7.875  -38.447 -2.696  1   29.8   ? 264 SER A C   1 
ATOM   4257 O O   . SER B 2 268 ? -7.356  -37.748 -3.552  1   31.88  ? 264 SER A O   1 
ATOM   4258 C CB  . SER B 2 268 ? -7.066  -40.806 -2.874  1   31.11  ? 264 SER A CB  1 
ATOM   4259 O OG  . SER B 2 268 ? -8.401  -41.208 -3.136  1   32.39  ? 264 SER A OG  1 
ATOM   4260 N N   . GLN B 2 269 ? -9.141  -38.286 -2.313  1   29.24  ? 265 GLN A N   1 
ATOM   4261 C CA  . GLN B 2 269 ? -9.968  -37.247 -2.899  1   29.69  ? 265 GLN A CA  1 
ATOM   4262 C C   . GLN B 2 269 ? -9.741  -35.909 -2.21   1   30.32  ? 265 GLN A C   1 
ATOM   4263 O O   . GLN B 2 269 ? -10.087 -34.859 -2.738  1   30.32  ? 265 GLN A O   1 
ATOM   4264 C CB  . GLN B 2 269 ? -11.43  -37.64  -2.776  1   30.21  ? 265 GLN A CB  1 
ATOM   4265 C CG  . GLN B 2 269 ? -11.746 -38.873 -3.606  1   33.68  ? 265 GLN A CG  1 
ATOM   4266 C CD  . GLN B 2 269 ? -13.21  -39.191 -3.543  1   36.64  ? 265 GLN A CD  1 
ATOM   4267 O OE1 . GLN B 2 269 ? -13.635 -40.165 -2.906  1   37.1   ? 265 GLN A OE1 1 
ATOM   4268 N NE2 . GLN B 2 269 ? -13.979 -38.293 -4.142  1   39.84  ? 265 GLN A NE2 1 
ATOM   4269 N N   . MET B 2 270 ? -9.168  -35.951 -1.012  1   31.57  ? 266 MET A N   1 
ATOM   4270 C CA  . MET B 2 270 ? -8.828  -34.714 -0.339  1   31.44  ? 266 MET A CA  1 
ATOM   4271 C C   . MET B 2 270 ? -7.525  -34.149 -0.908  1   34.49  ? 266 MET A C   1 
ATOM   4272 O O   . MET B 2 270 ? -7.359  -32.928 -0.93   1   41.78  ? 266 MET A O   1 
ATOM   4273 C CB  . MET B 2 270 ? -8.798  -34.933 1.174   1   27.92  ? 266 MET A CB  1 
ATOM   4274 C CG  . MET B 2 270 ? -10.177 -35.249 1.705   1   27.06  ? 266 MET A CG  1 
ATOM   4275 S SD  . MET B 2 270 ? -10.279 -35.575 3.474   1   27.12  ? 266 MET A SD  1 
ATOM   4276 C CE  . MET B 2 270 ? -10.074 -33.91  4.099   1   25.41  ? 266 MET A CE  1 
ATOM   4277 N N   . LEU B 2 271 ? -6.625  -35.025 -1.391  1   31.44  ? 267 LEU A N   1 
ATOM   4278 C CA  . LEU B 2 271 ? -5.284  -34.624 -1.791  1   27.31  ? 267 LEU A CA  1 
ATOM   4279 C C   . LEU B 2 271 ? -5.169  -34.671 -3.304  1   28.59  ? 267 LEU A C   1 
ATOM   4280 O O   . LEU B 2 271 ? -4.062  -34.75  -3.815  1   28.19  ? 267 LEU A O   1 
ATOM   4281 C CB  . LEU B 2 271 ? -4.247  -35.57  -1.2    1   24.99  ? 267 LEU A CB  1 
ATOM   4282 C CG  . LEU B 2 271 ? -4.156  -35.63  0.322   1   24.72  ? 267 LEU A CG  1 
ATOM   4283 C CD1 . LEU B 2 271 ? -3.111  -36.649 0.742   1   24.67  ? 267 LEU A CD1 1 
ATOM   4284 C CD2 . LEU B 2 271 ? -3.872  -34.271 0.92    1   23.53  ? 267 LEU A CD2 1 
ATOM   4285 N N   . HIS B 2 272 ? -6.301  -34.68  -4.008  1   31.04  ? 268 HIS A N   1 
ATOM   4286 C CA  . HIS B 2 272 ? -6.271  -34.521 -5.452  1   34.49  ? 268 HIS A CA  1 
ATOM   4287 C C   . HIS B 2 272 ? -5.499  -33.225 -5.749  1   33.97  ? 268 HIS A C   1 
ATOM   4288 O O   . HIS B 2 272 ? -5.704  -32.211 -5.068  1   29.29  ? 268 HIS A O   1 
ATOM   4289 C CB  . HIS B 2 272 ? -7.704  -34.575 -5.999  1   38.76  ? 268 HIS A CB  1 
ATOM   4290 C CG  . HIS B 2 272 ? -7.838  -35.083 -7.393  1   52.21  ? 268 HIS A CG  1 
ATOM   4291 N ND1 . HIS B 2 272 ? -8.544  -36.236 -7.675  1   63.08  ? 268 HIS A ND1 1 
ATOM   4292 C CD2 . HIS B 2 272 ? -7.388  -34.614 -8.586  1   57.01  ? 268 HIS A CD2 1 
ATOM   4293 C CE1 . HIS B 2 272 ? -8.508  -36.453 -8.997  1   70.91  ? 268 HIS A CE1 1 
ATOM   4294 N NE2 . HIS B 2 272 ? -7.807  -35.478 -9.567  1   63.82  ? 268 HIS A NE2 1 
ATOM   4295 N N   . TYR B 2 273 ? -4.561  -33.296 -6.713  1   32.7   ? 269 TYR A N   1 
ATOM   4296 C CA  . TYR B 2 273 ? -3.826  -32.13  -7.174  1   30.69  ? 269 TYR A CA  1 
ATOM   4297 C C   . TYR B 2 273 ? -4.768  -31.041 -7.69   1   31.89  ? 269 TYR A C   1 
ATOM   4298 O O   . TYR B 2 273 ? -4.715  -29.908 -7.231  1   34.87  ? 269 TYR A O   1 
ATOM   4299 C CB  . TYR B 2 273 ? -2.854  -32.495 -8.289  1   30.2   ? 269 TYR A CB  1 
ATOM   4300 C CG  . TYR B 2 273 ? -1.503  -32.971 -7.794  1   29.71  ? 269 TYR A CG  1 
ATOM   4301 C CD1 . TYR B 2 273 ? -0.644  -32.099 -7.134  1   30.47  ? 269 TYR A CD1 1 
ATOM   4302 C CD2 . TYR B 2 273 ? -1.072  -34.264 -8.027  1   30.09  ? 269 TYR A CD2 1 
ATOM   4303 C CE1 . TYR B 2 273 ? 0.598   -32.507 -6.686  1   30.18  ? 269 TYR A CE1 1 
ATOM   4304 C CE2 . TYR B 2 273 ? 0.172   -34.686 -7.591  1   31.32  ? 269 TYR A CE2 1 
ATOM   4305 C CZ  . TYR B 2 273 ? 1.007   -33.81  -6.919  1   32.46  ? 269 TYR A CZ  1 
ATOM   4306 O OH  . TYR B 2 273 ? 2.242   -34.238 -6.502  1   35.94  ? 269 TYR A OH  1 
ATOM   4307 N N   . ASP B 2 274 ? -5.615  -31.385 -8.661  1   30.87  ? 270 ASP A N   1 
ATOM   4308 C CA  . ASP B 2 274 ? -6.48   -30.417 -9.311  1   29.68  ? 270 ASP A CA  1 
ATOM   4309 C C   . ASP B 2 274 ? -7.536  -29.917 -8.328  1   30.85  ? 270 ASP A C   1 
ATOM   4310 O O   . ASP B 2 274 ? -8.42   -30.666 -7.929  1   33.9   ? 270 ASP A O   1 
ATOM   4311 C CB  . ASP B 2 274 ? -7.115  -31.066 -10.525 1   31.61  ? 270 ASP A CB  1 
ATOM   4312 C CG  . ASP B 2 274 ? -8.03   -30.165 -11.339 1   34.53  ? 270 ASP A CG  1 
ATOM   4313 O OD1 . ASP B 2 274 ? -8.229  -28.999 -10.896 1   33.51  ? 270 ASP A OD1 1 
ATOM   4314 O OD2 . ASP B 2 274 ? -8.497  -30.635 -12.422 1   35.55  ? 270 ASP A OD2 1 
ATOM   4315 N N   . PRO B 2 275 ? -7.548  -28.628 -7.918  1   30.26  ? 271 PRO A N   1 
ATOM   4316 C CA  . PRO B 2 275 ? -8.598  -28.113 -7.037  1   28.11  ? 271 PRO A CA  1 
ATOM   4317 C C   . PRO B 2 275 ? -10.039 -28.275 -7.513  1   30.81  ? 271 PRO A C   1 
ATOM   4318 O O   . PRO B 2 275 ? -10.964 -28.214 -6.714  1   31.75  ? 271 PRO A O   1 
ATOM   4319 C CB  . PRO B 2 275 ? -8.22   -26.641 -6.953  1   26.9   ? 271 PRO A CB  1 
ATOM   4320 C CG  . PRO B 2 275 ? -6.745  -26.689 -7.05   1   26.59  ? 271 PRO A CG  1 
ATOM   4321 C CD  . PRO B 2 275 ? -6.56   -27.6   -8.248  1   29.15  ? 271 PRO A CD  1 
ATOM   4322 N N   . ASN B 2 276 ? -10.254 -28.472 -8.818  1   34.89  ? 272 ASN A N   1 
ATOM   4323 C CA  . ASN B 2 276 ? -11.612 -28.695 -9.304  1   35.6   ? 272 ASN A CA  1 
ATOM   4324 C C   . ASN B 2 276 ? -12.096 -30.101 -8.941  1   34.95  ? 272 ASN A C   1 
ATOM   4325 O O   . ASN B 2 276 ? -13.285 -30.27  -8.723  1   37.01  ? 272 ASN A O   1 
ATOM   4326 C CB  . ASN B 2 276 ? -11.776 -28.372 -10.786 1   37.44  ? 272 ASN A CB  1 
ATOM   4327 C CG  . ASN B 2 276 ? -11.372 -26.954 -11.124 1   38.94  ? 272 ASN A CG  1 
ATOM   4328 O OD1 . ASN B 2 276 ? -11.934 -25.985 -10.591 1   41.21  ? 272 ASN A OD1 1 
ATOM   4329 N ND2 . ASN B 2 276 ? -10.38  -26.813 -11.992 1   38.02  ? 272 ASN A ND2 1 
ATOM   4330 N N   . LYS B 2 277 ? -11.189 -31.087 -8.844  1   33.56  ? 273 LYS A N   1 
ATOM   4331 C CA  . LYS B 2 277 ? -11.544 -32.487 -8.672  1   33.47  ? 273 LYS A CA  1 
ATOM   4332 C C   . LYS B 2 277 ? -11.555 -32.864 -7.195  1   29.56  ? 273 LYS A C   1 
ATOM   4333 O O   . LYS B 2 277 ? -12.111 -33.889 -6.812  1   27.87  ? 273 LYS A O   1 
ATOM   4334 C CB  . LYS B 2 277 ? -10.54  -33.4   -9.386  1   38.93  ? 273 LYS A CB  1 
ATOM   4335 C CG  . LYS B 2 277 ? -10.582 -33.475 -10.906 1   46.74  ? 273 LYS A CG  1 
ATOM   4336 C CD  . LYS B 2 277 ? -12.008 -33.344 -11.447 1   57.19  ? 273 LYS A CD  1 
ATOM   4337 C CE  . LYS B 2 277 ? -12.191 -33.607 -12.926 1   61.27  ? 273 LYS A CE  1 
ATOM   4338 N NZ  . LYS B 2 277 ? -13.425 -32.966 -13.39  1   59.2   ? 273 LYS A NZ  1 
ATOM   4339 N N   . ARG B 2 278 ? -10.915 -32.031 -6.371  1   27.43  ? 274 ARG A N   1 
ATOM   4340 C CA  . ARG B 2 278 ? -10.749 -32.306 -4.952  1   25.14  ? 274 ARG A CA  1 
ATOM   4341 C C   . ARG B 2 278 ? -12.123 -32.256 -4.286  1   24.89  ? 274 ARG A C   1 
ATOM   4342 O O   . ARG B 2 278 ? -12.967 -31.459 -4.667  1   27.61  ? 274 ARG A O   1 
ATOM   4343 C CB  . ARG B 2 278 ? -9.794  -31.248 -4.403  1   23.55  ? 274 ARG A CB  1 
ATOM   4344 C CG  . ARG B 2 278 ? -8.896  -31.749 -3.289  1   24.98  ? 274 ARG A CG  1 
ATOM   4345 C CD  . ARG B 2 278 ? -8.078  -30.597 -2.746  1   25.74  ? 274 ARG A CD  1 
ATOM   4346 N NE  . ARG B 2 278 ? -7.1    -30.126 -3.726  1   27.81  ? 274 ARG A NE  1 
ATOM   4347 C CZ  . ARG B 2 278 ? -6.437  -28.973 -3.648  1   28.1   ? 274 ARG A CZ  1 
ATOM   4348 N NH1 . ARG B 2 278 ? -6.671  -28.118 -2.673  1   25.56  ? 274 ARG A NH1 1 
ATOM   4349 N NH2 . ARG B 2 278 ? -5.535  -28.667 -4.563  1   29.26  ? 274 ARG A NH2 1 
ATOM   4350 N N   . ILE B 2 279 ? -12.371 -33.121 -3.307  1   22.75  ? 275 ILE A N   1 
ATOM   4351 C CA  . ILE B 2 279 ? -13.703 -33.271 -2.74   1   22.06  ? 275 ILE A CA  1 
ATOM   4352 C C   . ILE B 2 279 ? -14.045 -32.028 -1.916  1   22.94  ? 275 ILE A C   1 
ATOM   4353 O O   . ILE B 2 279 ? -13.158 -31.274 -1.502  1   24.26  ? 275 ILE A O   1 
ATOM   4354 C CB  . ILE B 2 279 ? -13.758 -34.578 -1.929  1   21.57  ? 275 ILE A CB  1 
ATOM   4355 C CG1 . ILE B 2 279 ? -15.153 -35.062 -1.61   1   22.56  ? 275 ILE A CG1 1 
ATOM   4356 C CG2 . ILE B 2 279 ? -12.9   -34.488 -0.673  1   20.55  ? 275 ILE A CG2 1 
ATOM   4357 C CD1 . ILE B 2 279 ? -15.204 -36.501 -1.133  1   22.98  ? 275 ILE A CD1 1 
ATOM   4358 N N   . SER B 2 280 ? -15.343 -31.801 -1.7    1   23.86  ? 276 SER A N   1 
ATOM   4359 C CA  . SER B 2 280 ? -15.834 -30.693 -0.895  1   24.63  ? 276 SER A CA  1 
ATOM   4360 C C   . SER B 2 280 ? -16.162 -31.187 0.512   1   26.77  ? 276 SER A C   1 
ATOM   4361 O O   . SER B 2 280 ? -16.52  -32.354 0.686   1   29.03  ? 276 SER A O   1 
ATOM   4362 C CB  . SER B 2 280 ? -17.087 -30.118 -1.497  1   25.37  ? 276 SER A CB  1 
ATOM   4363 O OG  . SER B 2 280 ? -18.165 -31.02  -1.298  1   24.78  ? 276 SER A OG  1 
ATOM   4364 N N   . ALA B 2 281 ? -16.108 -30.29  1.51    1   25.02  ? 277 ALA A N   1 
ATOM   4365 C CA  . ALA B 2 281 ? -16.481 -30.71  2.854   1   24.2   ? 277 ALA A CA  1 
ATOM   4366 C C   . ALA B 2 281 ? -17.866 -31.346 2.823   1   23.95  ? 277 ALA A C   1 
ATOM   4367 O O   . ALA B 2 281 ? -18.112 -32.374 3.436   1   24.88  ? 277 ALA A O   1 
ATOM   4368 C CB  . ALA B 2 281 ? -16.47  -29.539 3.796   1   24.1   ? 277 ALA A CB  1 
ATOM   4369 N N   . LYS B 2 282 ? -18.772 -30.713 2.092   1   23.25  ? 278 LYS A N   1 
ATOM   4370 C CA  . LYS B 2 282 ? -20.162 -31.119 2.075   1   23.74  ? 278 LYS A CA  1 
ATOM   4371 C C   . LYS B 2 282 ? -20.279 -32.545 1.523   1   26.68  ? 278 LYS A C   1 
ATOM   4372 O O   . LYS B 2 282 ? -20.954 -33.394 2.109   1   27.85  ? 278 LYS A O   1 
ATOM   4373 C CB  . LYS B 2 282 ? -20.861 -29.975 1.341   1   22.15  ? 278 LYS A CB  1 
ATOM   4374 C CG  . LYS B 2 282 ? -22.268 -30.157 0.925   1   22.93  ? 278 LYS A CG  1 
ATOM   4375 C CD  . LYS B 2 282 ? -22.648 -28.993 0.018   1   23.88  ? 278 LYS A CD  1 
ATOM   4376 C CE  . LYS B 2 282 ? -23.104 -27.793 0.806   1   24.08  ? 278 LYS A CE  1 
ATOM   4377 N NZ  . LYS B 2 282 ? -23.947 -26.897 -0.003  1   24.99  ? 278 LYS A NZ  1 
ATOM   4378 N N   . ALA B 2 283 ? -19.566 -32.846 0.432   1   28.62  ? 279 ALA A N   1 
ATOM   4379 C CA  . ALA B 2 283 ? -19.682 -34.155 -0.211  1   30.8   ? 279 ALA A CA  1 
ATOM   4380 C C   . ALA B 2 283 ? -18.959 -35.243 0.588   1   32.51  ? 279 ALA A C   1 
ATOM   4381 O O   . ALA B 2 283 ? -19.349 -36.409 0.489   1   35.48  ? 279 ALA A O   1 
ATOM   4382 C CB  . ALA B 2 283 ? -19.155 -34.105 -1.63   1   29.37  ? 279 ALA A CB  1 
ATOM   4383 N N   . ALA B 2 284 ? -17.888 -34.869 1.327   1   28.24  ? 280 ALA A N   1 
ATOM   4384 C CA  . ALA B 2 284 ? -17.056 -35.814 2.048   1   24.79  ? 280 ALA A CA  1 
ATOM   4385 C C   . ALA B 2 284 ? -17.829 -36.399 3.224   1   26.63  ? 280 ALA A C   1 
ATOM   4386 O O   . ALA B 2 284 ? -17.651 -37.576 3.517   1   29.6   ? 280 ALA A O   1 
ATOM   4387 C CB  . ALA B 2 284 ? -15.799 -35.163 2.492   1   21.28  ? 280 ALA A CB  1 
ATOM   4388 N N   . LEU B 2 285 ? -18.692 -35.594 3.872   1   25.43  ? 281 LEU A N   1 
ATOM   4389 C CA  . LEU B 2 285 ? -19.537 -36.029 4.976   1   25.38  ? 281 LEU A CA  1 
ATOM   4390 C C   . LEU B 2 285 ? -20.289 -37.316 4.629   1   28.74  ? 281 LEU A C   1 
ATOM   4391 O O   . LEU B 2 285 ? -20.652 -38.075 5.527   1   31.55  ? 281 LEU A O   1 
ATOM   4392 C CB  . LEU B 2 285 ? -20.537 -34.93  5.321   1   24.34  ? 281 LEU A CB  1 
ATOM   4393 C CG  . LEU B 2 285 ? -20.007 -33.738 6.116   1   22.37  ? 281 LEU A CG  1 
ATOM   4394 C CD1 . LEU B 2 285 ? -21.027 -32.661 6.219   1   21.66  ? 281 LEU A CD1 1 
ATOM   4395 C CD2 . LEU B 2 285 ? -19.663 -34.161 7.516   1   22.38  ? 281 LEU A CD2 1 
ATOM   4396 N N   . ALA B 2 286 ? -20.569 -37.534 3.338   1   27.78  ? 282 ALA A N   1 
ATOM   4397 C CA  . ALA B 2 286 ? -21.393 -38.644 2.913   1   29.38  ? 282 ALA A CA  1 
ATOM   4398 C C   . ALA B 2 286 ? -20.545 -39.854 2.523   1   30.36  ? 282 ALA A C   1 
ATOM   4399 O O   . ALA B 2 286 ? -21.088 -40.885 2.104   1   32.94  ? 282 ALA A O   1 
ATOM   4400 C CB  . ALA B 2 286 ? -22.255 -38.186 1.761   1   31.25  ? 282 ALA A CB  1 
ATOM   4401 N N   . HIS B 2 287 ? -19.22  -39.734 2.663   1   28.53  ? 283 HIS A N   1 
ATOM   4402 C CA  . HIS B 2 287 ? -18.317 -40.793 2.231   1   29     ? 283 HIS A CA  1 
ATOM   4403 C C   . HIS B 2 287 ? -18.545 -42.04  3.081   1   29.43  ? 283 HIS A C   1 
ATOM   4404 O O   . HIS B 2 287 ? -18.913 -41.924 4.244   1   28.9   ? 283 HIS A O   1 
ATOM   4405 C CB  . HIS B 2 287 ? -16.863 -40.312 2.232   1   28.17  ? 283 HIS A CB  1 
ATOM   4406 C CG  . HIS B 2 287 ? -15.94  -41.186 1.44    1   30.26  ? 283 HIS A CG  1 
ATOM   4407 N ND1 . HIS B 2 287 ? -15.585 -42.46  1.832   1   32.14  ? 283 HIS A ND1 1 
ATOM   4408 C CD2 . HIS B 2 287 ? -15.309 -40.98  0.276   1   30.33  ? 283 HIS A CD2 1 
ATOM   4409 C CE1 . HIS B 2 287 ? -14.75  -42.985 0.945   1   32.58  ? 283 HIS A CE1 1 
ATOM   4410 N NE2 . HIS B 2 287 ? -14.57  -42.106 -0.015  1   31.47  ? 283 HIS A NE2 1 
ATOM   4411 N N   . PRO B 2 288 ? -18.401 -43.263 2.509   1   30.68  ? 284 PRO A N   1 
ATOM   4412 C CA  . PRO B 2 288 ? -18.54  -44.513 3.266   1   32.36  ? 284 PRO A CA  1 
ATOM   4413 C C   . PRO B 2 288 ? -17.615 -44.701 4.471   1   31.52  ? 284 PRO A C   1 
ATOM   4414 O O   . PRO B 2 288 ? -17.967 -45.403 5.427   1   31.95  ? 284 PRO A O   1 
ATOM   4415 C CB  . PRO B 2 288 ? -18.281 -45.541 2.175   1   33.47  ? 284 PRO A CB  1 
ATOM   4416 C CG  . PRO B 2 288 ? -18.836 -44.876 0.968   1   33.1   ? 284 PRO A CG  1 
ATOM   4417 C CD  . PRO B 2 288 ? -18.17  -43.529 1.083   1   30.84  ? 284 PRO A CD  1 
ATOM   4418 N N   . PHE B 2 289 ? -16.455 -44.03  4.424   1   29.61  ? 285 PHE A N   1 
ATOM   4419 C CA  . PHE B 2 289 ? -15.505 -44.042 5.523   1   29.53  ? 285 PHE A CA  1 
ATOM   4420 C C   . PHE B 2 289 ? -16.199 -43.769 6.862   1   29.2   ? 285 PHE A C   1 
ATOM   4421 O O   . PHE B 2 289 ? -15.736 -44.238 7.899   1   28.98  ? 285 PHE A O   1 
ATOM   4422 C CB  . PHE B 2 289 ? -14.376 -43.025 5.335   1   27.8   ? 285 PHE A CB  1 
ATOM   4423 C CG  . PHE B 2 289 ? -13.369 -43.017 6.477   1   27.57  ? 285 PHE A CG  1 
ATOM   4424 C CD1 . PHE B 2 289 ? -12.564 -44.138 6.726   1   28.79  ? 285 PHE A CD1 1 
ATOM   4425 C CD2 . PHE B 2 289 ? -13.206 -41.88  7.272   1   25.9   ? 285 PHE A CD2 1 
ATOM   4426 C CE1 . PHE B 2 289 ? -11.626 -44.131 7.75    1   28.49  ? 285 PHE A CE1 1 
ATOM   4427 C CE2 . PHE B 2 289 ? -12.268 -41.875 8.303   1   25.96  ? 285 PHE A CE2 1 
ATOM   4428 C CZ  . PHE B 2 289 ? -11.484 -43     8.541   1   27.4   ? 285 PHE A CZ  1 
ATOM   4429 N N   . PHE B 2 290 ? -17.269 -42.972 6.843   1   28.8   ? 286 PHE A N   1 
ATOM   4430 C CA  . PHE B 2 290 ? -17.921 -42.579 8.071   1   29.93  ? 286 PHE A CA  1 
ATOM   4431 C C   . PHE B 2 290 ? -19.159 -43.432 8.333   1   35.43  ? 286 PHE A C   1 
ATOM   4432 O O   . PHE B 2 290 ? -19.892 -43.129 9.274   1   35.78  ? 286 PHE A O   1 
ATOM   4433 C CB  . PHE B 2 290 ? -18.32  -41.107 8.046   1   26.81  ? 286 PHE A CB  1 
ATOM   4434 C CG  . PHE B 2 290 ? -17.189 -40.14  7.771   1   24.5   ? 286 PHE A CG  1 
ATOM   4435 C CD1 . PHE B 2 290 ? -16.263 -39.85  8.756   1   23.37  ? 286 PHE A CD1 1 
ATOM   4436 C CD2 . PHE B 2 290 ? -17.076 -39.489 6.546   1   23.55  ? 286 PHE A CD2 1 
ATOM   4437 C CE1 . PHE B 2 290 ? -15.252 -38.934 8.507   1   22.11  ? 286 PHE A CE1 1 
ATOM   4438 C CE2 . PHE B 2 290 ? -16.044 -38.583 6.316   1   21.44  ? 286 PHE A CE2 1 
ATOM   4439 C CZ  . PHE B 2 290 ? -15.13  -38.301 7.292   1   20.35  ? 286 PHE A CZ  1 
ATOM   4440 N N   . GLN B 2 291 ? -19.359 -44.522 7.574   1   41.05  ? 287 GLN A N   1 
ATOM   4441 C CA  . GLN B 2 291 ? -20.587 -45.287 7.743   1   47.28  ? 287 GLN A CA  1 
ATOM   4442 C C   . GLN B 2 291 ? -20.832 -45.618 9.219   1   48.11  ? 287 GLN A C   1 
ATOM   4443 O O   . GLN B 2 291 ? -21.975 -45.674 9.646   1   53.75  ? 287 GLN A O   1 
ATOM   4444 C CB  . GLN B 2 291 ? -20.79  -46.423 6.736   1   55.6   ? 287 GLN A CB  1 
ATOM   4445 C CG  . GLN B 2 291 ? -19.74  -47.53  6.813   1   69.84  ? 287 GLN A CG  1 
ATOM   4446 C CD  . GLN B 2 291 ? -19.756 -48.506 5.647   1   80.39  ? 287 GLN A CD  1 
ATOM   4447 O OE1 . GLN B 2 291 ? -20.552 -49.453 5.622   1   88.11  ? 287 GLN A OE1 1 
ATOM   4448 N NE2 . GLN B 2 291 ? -18.838 -48.327 4.698   1   78.49  ? 287 GLN A NE2 1 
ATOM   4449 N N   . ASP B 2 292 ? -19.786 -45.782 10.033  1   47.13  ? 288 ASP A N   1 
ATOM   4450 C CA  . ASP B 2 292 ? -20.001 -46.329 11.362  1   48.09  ? 288 ASP A CA  1 
ATOM   4451 C C   . ASP B 2 292 ? -19.888 -45.303 12.476  1   43.91  ? 288 ASP A C   1 
ATOM   4452 O O   . ASP B 2 292 ? -20.04  -45.668 13.64   1   42.14  ? 288 ASP A O   1 
ATOM   4453 C CB  . ASP B 2 292 ? -19.077 -47.505 11.594  1   56.39  ? 288 ASP A CB  1 
ATOM   4454 C CG  . ASP B 2 292 ? -19.735 -48.844 11.298  1   66.92  ? 288 ASP A CG  1 
ATOM   4455 O OD1 . ASP B 2 292 ? -20.992 -48.95  11.436  1   69.43  ? 288 ASP A OD1 1 
ATOM   4456 O OD2 . ASP B 2 292 ? -18.994 -49.758 10.885  1   73.01  ? 288 ASP A OD2 1 
ATOM   4457 N N   . VAL B 2 293 ? -19.67  -44.034 12.1    1   42.58  ? 289 VAL A N   1 
ATOM   4458 C CA  . VAL B 2 293 ? -19.094 -43.017 12.977  1   40.83  ? 289 VAL A CA  1 
ATOM   4459 C C   . VAL B 2 293 ? -19.957 -42.814 14.224  1   40.24  ? 289 VAL A C   1 
ATOM   4460 O O   . VAL B 2 293 ? -21.181 -42.937 14.17   1   41.95  ? 289 VAL A O   1 
ATOM   4461 C CB  . VAL B 2 293 ? -18.811 -41.689 12.235  1   37.42  ? 289 VAL A CB  1 
ATOM   4462 C CG1 . VAL B 2 293 ? -20.081 -40.943 11.865  1   35.08  ? 289 VAL A CG1 1 
ATOM   4463 C CG2 . VAL B 2 293 ? -17.907 -40.761 13.039  1   35.88  ? 289 VAL A CG2 1 
ATOM   4464 N N   . THR B 2 294 ? -19.298 -42.513 15.344  1   38.59  ? 290 THR A N   1 
ATOM   4465 C CA  . THR B 2 294 ? -19.99  -41.969 16.503  1   40.83  ? 290 THR A CA  1 
ATOM   4466 C C   . THR B 2 294 ? -19.147 -40.811 17.026  1   40.58  ? 290 THR A C   1 
ATOM   4467 O O   . THR B 2 294 ? -18.22  -40.396 16.33   1   42.51  ? 290 THR A O   1 
ATOM   4468 C CB  . THR B 2 294 ? -20.284 -43.032 17.566  1   43.16  ? 290 THR A CB  1 
ATOM   4469 O OG1 . THR B 2 294 ? -19.08  -43.625 18.05   1   41.27  ? 290 THR A OG1 1 
ATOM   4470 C CG2 . THR B 2 294 ? -21.208 -44.124 17.057  1   46.6   ? 290 THR A CG2 1 
ATOM   4471 N N   . LYS B 2 295 ? -19.444 -40.322 18.236  1   38.21  ? 291 LYS A N   1 
ATOM   4472 C CA  . LYS B 2 295 ? -18.645 -39.274 18.839  1   36.1   ? 291 LYS A CA  1 
ATOM   4473 C C   . LYS B 2 295 ? -18.166 -39.722 20.215  1   37.48  ? 291 LYS A C   1 
ATOM   4474 O O   . LYS B 2 295 ? -18.656 -39.223 21.223  1   40.48  ? 291 LYS A O   1 
ATOM   4475 C CB  . LYS B 2 295 ? -19.486 -37.994 18.909  1   37.48  ? 291 LYS A CB  1 
ATOM   4476 C CG  . LYS B 2 295 ? -18.975 -36.857 19.799  1   37.62  ? 291 LYS A CG  1 
ATOM   4477 C CD  . LYS B 2 295 ? -19.533 -35.535 19.302  1   41.57  ? 291 LYS A CD  1 
ATOM   4478 C CE  . LYS B 2 295 ? -19.062 -34.283 19.989  1   49.01  ? 291 LYS A CE  1 
ATOM   4479 N NZ  . LYS B 2 295 ? -19.481 -33.068 19.267  1   46.54  ? 291 LYS A NZ  1 
ATOM   4480 N N   . PRO B 2 296 ? -17.197 -40.66  20.332  1   37.12  ? 292 PRO A N   1 
ATOM   4481 C CA  . PRO B 2 296 ? -16.653 -41.008 21.648  1   38.62  ? 292 PRO A CA  1 
ATOM   4482 C C   . PRO B 2 296 ? -15.748 -39.897 22.199  1   41.23  ? 292 PRO A C   1 
ATOM   4483 O O   . PRO B 2 296 ? -15.267 -39.038 21.429  1   43.73  ? 292 PRO A O   1 
ATOM   4484 C CB  . PRO B 2 296 ? -15.909 -42.315 21.341  1   37.43  ? 292 PRO A CB  1 
ATOM   4485 C CG  . PRO B 2 296 ? -15.468 -42.18  19.902  1   34.95  ? 292 PRO A CG  1 
ATOM   4486 C CD  . PRO B 2 296 ? -16.568 -41.405 19.231  1   34.98  ? 292 PRO A CD  1 
ATOM   4487 N N   . VAL B 2 297 ? -15.562 -39.918 23.534  1   40.04  ? 293 VAL A N   1 
ATOM   4488 C CA  . VAL B 2 297 ? -14.69  -39.023 24.287  1   37.92  ? 293 VAL A CA  1 
ATOM   4489 C C   . VAL B 2 297 ? -13.246 -39.424 24.015  1   39.09  ? 293 VAL A C   1 
ATOM   4490 O O   . VAL B 2 297 ? -12.999 -40.597 23.721  1   40.63  ? 293 VAL A O   1 
ATOM   4491 C CB  . VAL B 2 297 ? -14.952 -39.08  25.806  1   37.37  ? 293 VAL A CB  1 
ATOM   4492 C CG1 . VAL B 2 297 ? -16.404 -38.794 26.134  1   39.02  ? 293 VAL A CG1 1 
ATOM   4493 C CG2 . VAL B 2 297 ? -14.543 -40.397 26.436  1   37.69  ? 293 VAL A CG2 1 
ATOM   4494 N N   . PRO B 2 298 ? -12.252 -38.499 24.142  1   37.26  ? 294 PRO A N   1 
ATOM   4495 C CA  . PRO B 2 298 ? -10.848 -38.881 24.048  1   37.03  ? 294 PRO A CA  1 
ATOM   4496 C C   . PRO B 2 298 ? -10.51  -39.94  25.098  1   40.17  ? 294 PRO A C   1 
ATOM   4497 O O   . PRO B 2 298 ? -11.077 -39.947 26.19   1   42.16  ? 294 PRO A O   1 
ATOM   4498 C CB  . PRO B 2 298 ? -10.11  -37.562 24.241  1   34.83  ? 294 PRO A CB  1 
ATOM   4499 C CG  . PRO B 2 298 ? -11.075 -36.687 24.956  1   34.07  ? 294 PRO A CG  1 
ATOM   4500 C CD  . PRO B 2 298 ? -12.409 -37.053 24.358  1   34.29  ? 294 PRO A CD  1 
ATOM   4501 N N   . HIS B 2 299 ? -9.595  -40.842 24.729  1   41.27  ? 295 HIS A N   1 
ATOM   4502 C CA  . HIS B 2 299 ? -9.284  -42.048 25.481  1   43.48  ? 295 HIS A CA  1 
ATOM   4503 C C   . HIS B 2 299 ? -8.147  -41.791 26.479  1   47.02  ? 295 HIS A C   1 
ATOM   4504 O O   . HIS B 2 299 ? -7.697  -42.725 27.153  1   48.93  ? 295 HIS A O   1 
ATOM   4505 C CB  . HIS B 2 299 ? -8.876  -43.158 24.501  1   42.2   ? 295 HIS A CB  1 
ATOM   4506 C CG  . HIS B 2 299 ? -7.57   -42.873 23.84   1   40.81  ? 295 HIS A CG  1 
ATOM   4507 N ND1 . HIS B 2 299 ? -6.504  -43.754 23.873  1   43.24  ? 295 HIS A ND1 1 
ATOM   4508 C CD2 . HIS B 2 299 ? -7.136  -41.783 23.202  1   37.89  ? 295 HIS A CD2 1 
ATOM   4509 C CE1 . HIS B 2 299 ? -5.459  -43.211 23.263  1   41.77  ? 295 HIS A CE1 1 
ATOM   4510 N NE2 . HIS B 2 299 ? -5.825  -42.008 22.852  1   39.19  ? 295 HIS A NE2 1 
ATOM   4511 N N   . LEU B 2 300 ? -7.656  -40.559 26.493  1   46.9   ? 296 LEU A N   1 
ATOM   4512 C CA  . LEU B 2 300 ? -6.605  -40.155 27.438  1   48.87  ? 296 LEU A CA  1 
ATOM   4513 C C   . LEU B 2 300 ? -7.112  -38.863 28.077  1   51.37  ? 296 LEU A C   1 
ATOM   4514 O O   . LEU B 2 300 ? -7.98   -38.22  27.476  1   50.81  ? 296 LEU A O   1 
ATOM   4515 C CB  . LEU B 2 300 ? -5.282  -39.946 26.706  1   45.79  ? 296 LEU A CB  1 
ATOM   4516 C CG  . LEU B 2 300 ? -4.645  -41.152 26.016  1   45.21  ? 296 LEU A CG  1 
ATOM   4517 C CD1 . LEU B 2 300 ? -3.62   -40.598 25.059  1   44.82  ? 296 LEU A CD1 1 
ATOM   4518 C CD2 . LEU B 2 300 ? -3.992  -42.097 26.996  1   46.32  ? 296 LEU A CD2 1 
ATOM   4519 N N   . ARG B 2 301 ? -6.576  -38.497 29.238  1   53.28  ? 297 ARG A N   1 
ATOM   4520 C CA  . ARG B 2 301 ? -7.078  -37.298 29.955  1   54.51  ? 297 ARG A CA  1 
ATOM   4521 C C   . ARG B 2 301 ? -6.406  -36.036 29.401  1   56.82  ? 297 ARG A C   1 
ATOM   4522 O O   . ARG B 2 301 ? -5.201  -36.087 29.107  1   56.18  ? 297 ARG A O   1 
ATOM   4523 C CB  . ARG B 2 301 ? -6.901  -37.466 31.466  1   53.7   ? 297 ARG A CB  1 
ATOM   4524 C CG  . ARG B 2 301 ? -7.92   -38.44  32.038  1   52.39  ? 297 ARG A CG  1 
ATOM   4525 C CD  . ARG B 2 301 ? -8.097  -38.303 33.536  1   51.43  ? 297 ARG A CD  1 
ATOM   4526 N NE  . ARG B 2 301 ? -7.407  -39.378 34.256  1   52.26  ? 297 ARG A NE  1 
ATOM   4527 C CZ  . ARG B 2 301 ? -7.492  -39.596 35.561  1   52.52  ? 297 ARG A CZ  1 
ATOM   4528 N NH1 . ARG B 2 301 ? -8.674  -39.703 36.141  1   53.95  ? 297 ARG A NH1 1 
ATOM   4529 N NH2 . ARG B 2 301 ? -6.393  -39.717 36.28   1   50.74  ? 297 ARG A NH2 1 
ATOM   4530 N N   . LEU B 2 302 ? -7.174  -34.954 29.264  1   59.12  ? 298 LEU A N   1 
ATOM   4531 C CA  . LEU B 2 302 ? -6.643  -33.683 28.707  1   61.79  ? 298 LEU A CA  1 
ATOM   4532 C C   . LEU B 2 302 ? -6.175  -32.783 29.862  1   65.23  ? 298 LEU A C   1 
ATOM   4533 O O   . LEU B 2 302 ? -5.107  -33.081 30.433  1   70.22  ? 298 LEU A O   1 
ATOM   4534 C CB  . LEU B 2 302 ? -7.653  -32.953 27.814  1   57.69  ? 298 LEU A CB  1 
ATOM   4535 C CG  . LEU B 2 302 ? -8.467  -33.795 26.828  1   53.13  ? 298 LEU A CG  1 
ATOM   4536 C CD1 . LEU B 2 302 ? -9.304  -32.841 26.008  1   45.02  ? 298 LEU A CD1 1 
ATOM   4537 C CD2 . LEU B 2 302 ? -7.589  -34.644 25.927  1   51.44  ? 298 LEU A CD2 1 
ATOM   4538 N N   . GLY C 1 1   ? -15.59  -24.943 -12.139 1   40.64  ? 171 GLY B N   1 
ATOM   4539 C CA  . GLY C 1 1   ? -14.448 -24.326 -11.445 1   43.64  ? 171 GLY B CA  1 
ATOM   4540 C C   . GLY C 1 1   ? -14.714 -24.228 -9.944  1   43.62  ? 171 GLY B C   1 
ATOM   4541 O O   . GLY C 1 1   ? -15.71  -23.621 -9.538  1   43.19  ? 171 GLY B O   1 
ATOM   4542 N N   . VAL C 1 2   ? -13.81  -24.799 -9.129  1   41.44  ? 172 VAL B N   1 
ATOM   4543 C CA  . VAL C 1 2   ? -13.838 -24.642 -7.68   1   38.64  ? 172 VAL B CA  1 
ATOM   4544 C C   . VAL C 1 2   ? -13.827 -23.153 -7.301  1   37.66  ? 172 VAL B C   1 
ATOM   4545 O O   . VAL C 1 2   ? -14.379 -22.788 -6.273  1   36.47  ? 172 VAL B O   1 
ATOM   4546 C CB  . VAL C 1 2   ? -12.694 -25.444 -7.02   1   37.76  ? 172 VAL B CB  1 
ATOM   4547 C CG1 . VAL C 1 2   ? -11.33  -24.839 -7.317  1   38.18  ? 172 VAL B CG1 1 
ATOM   4548 C CG2 . VAL C 1 2   ? -12.86  -25.588 -5.516  1   36.55  ? 172 VAL B CG2 1 
ATOM   4549 N N   . ASN C 1 3   ? -13.231 -22.298 -8.149  1   37.92  ? 173 ASN B N   1 
ATOM   4550 C CA  . ASN C 1 3   ? -13.212 -20.863 -7.943  1   34.24  ? 173 ASN B CA  1 
ATOM   4551 C C   . ASN C 1 3   ? -14.615 -20.263 -7.913  1   33.71  ? 173 ASN B C   1 
ATOM   4552 O O   . ASN C 1 3   ? -14.763 -19.113 -7.483  1   34.33  ? 173 ASN B O   1 
ATOM   4553 C CB  . ASN C 1 3   ? -12.333 -20.191 -8.984  1   34.49  ? 173 ASN B CB  1 
ATOM   4554 C CG  . ASN C 1 3   ? -10.9   -20.642 -8.842  1   37.25  ? 173 ASN B CG  1 
ATOM   4555 O OD1 . ASN C 1 3   ? -10.588 -21.452 -7.958  1   39.01  ? 173 ASN B OD1 1 
ATOM   4556 N ND2 . ASN C 1 3   ? -10.019 -20.145 -9.699  1   36.09  ? 173 ASN B ND2 1 
ATOM   4557 N N   . GLU C 1 4   ? -15.62  -21.017 -8.394  1   33.62  ? 174 GLU B N   1 
ATOM   4558 C CA  . GLU C 1 4   ? -17.015 -20.582 -8.368  1   34.3   ? 174 GLU B CA  1 
ATOM   4559 C C   . GLU C 1 4   ? -17.849 -21.494 -7.457  1   35.24  ? 174 GLU B C   1 
ATOM   4560 O O   . GLU C 1 4   ? -19.073 -21.585 -7.59   1   33.67  ? 174 GLU B O   1 
ATOM   4561 C CB  . GLU C 1 4   ? -17.632 -20.605 -9.769  1   37.67  ? 174 GLU B CB  1 
ATOM   4562 C CG  . GLU C 1 4   ? -16.629 -20.634 -10.923 1   42.38  ? 174 GLU B CG  1 
ATOM   4563 C CD  . GLU C 1 4   ? -17.344 -20.379 -12.238 1   48.53  ? 174 GLU B CD  1 
ATOM   4564 O OE1 . GLU C 1 4   ? -18.329 -21.092 -12.534 1   49.34  ? 174 GLU B OE1 1 
ATOM   4565 O OE2 . GLU C 1 4   ? -16.941 -19.435 -12.951 1   52.57  ? 174 GLU B OE2 1 
ATOM   4566 N N   . VAL C 1 5   ? -17.161 -22.241 -6.585  1   36.32  ? 175 VAL B N   1 
ATOM   4567 C CA  . VAL C 1 5   ? -17.782 -22.966 -5.49   1   37.01  ? 175 VAL B CA  1 
ATOM   4568 C C   . VAL C 1 5   ? -19.117 -23.561 -5.934  1   37.31  ? 175 VAL B C   1 
ATOM   4569 O O   . VAL C 1 5   ? -20.174 -23.206 -5.417  1   41.85  ? 175 VAL B O   1 
ATOM   4570 C CB  . VAL C 1 5   ? -17.889 -22.054 -4.241  1   36.76  ? 175 VAL B CB  1 
ATOM   4571 C CG1 . VAL C 1 5   ? -16.537 -21.921 -3.538  1   38.64  ? 175 VAL B CG1 1 
ATOM   4572 C CG2 . VAL C 1 5   ? -18.447 -20.66  -4.536  1   31.87  ? 175 VAL B CG2 1 
ATOM   4573 N N   . PRO C 1 6   ? -19.139 -24.501 -6.893  1   36.07  ? 176 PRO B N   1 
ATOM   4574 C CA  . PRO C 1 6   ? -20.359 -25.243 -7.223  1   37.7   ? 176 PRO B CA  1 
ATOM   4575 C C   . PRO C 1 6   ? -21.074 -25.913 -6.046  1   39.39  ? 176 PRO B C   1 
ATOM   4576 O O   . PRO C 1 6   ? -22.295 -25.939 -6.039  1   44.35  ? 176 PRO B O   1 
ATOM   4577 C CB  . PRO C 1 6   ? -19.907 -26.276 -8.266  1   36.34  ? 176 PRO B CB  1 
ATOM   4578 C CG  . PRO C 1 6   ? -18.426 -26.389 -8.03   1   36.38  ? 176 PRO B CG  1 
ATOM   4579 C CD  . PRO C 1 6   ? -17.995 -24.967 -7.669  1   36.23  ? 176 PRO B CD  1 
ATOM   4580 N N   . ASP C 1 7   ? -20.346 -26.45  -5.055  1   36.54  ? 177 ASP B N   1 
ATOM   4581 C CA  . ASP C 1 7   ? -21.029 -27.068 -3.93   1   34.4   ? 177 ASP B CA  1 
ATOM   4582 C C   . ASP C 1 7   ? -21.557 -26.037 -2.928  1   33.56  ? 177 ASP B C   1 
ATOM   4583 O O   . ASP C 1 7   ? -22.191 -26.446 -1.964  1   35.33  ? 177 ASP B O   1 
ATOM   4584 C CB  . ASP C 1 7   ? -20.203 -28.142 -3.247  1   34.89  ? 177 ASP B CB  1 
ATOM   4585 C CG  . ASP C 1 7   ? -20.074 -29.43  -4.036  1   38.04  ? 177 ASP B CG  1 
ATOM   4586 O OD1 . ASP C 1 7   ? -20.677 -29.485 -5.127  1   39.85  ? 177 ASP B OD1 1 
ATOM   4587 O OD2 . ASP C 1 7   ? -19.4   -30.366 -3.55   1   38.3   ? 177 ASP B OD2 1 
ATOM   4588 N N   . TYR C 1 8   ? -21.356 -24.727 -3.154  1   31.47  ? 178 TYR B N   1 
ATOM   4589 C CA  . TYR C 1 8   ? -21.644 -23.748 -2.113  1   31.28  ? 178 TYR B CA  1 
ATOM   4590 C C   . TYR C 1 8   ? -22.284 -22.461 -2.652  1   35.27  ? 178 TYR B C   1 
ATOM   4591 O O   . TYR C 1 8   ? -22.7   -21.627 -1.845  1   36.44  ? 178 TYR B O   1 
ATOM   4592 C CB  . TYR C 1 8   ? -20.411 -23.436 -1.251  1   28.34  ? 178 TYR B CB  1 
ATOM   4593 C CG  . TYR C 1 8   ? -19.794 -24.582 -0.448  1   27.23  ? 178 TYR B CG  1 
ATOM   4594 C CD1 . TYR C 1 8   ? -20.347 -25.006 0.759   1   27.13  ? 178 TYR B CD1 1 
ATOM   4595 C CD2 . TYR C 1 8   ? -18.66  -25.239 -0.907  1   26.77  ? 178 TYR B CD2 1 
ATOM   4596 C CE1 . TYR C 1 8   ? -19.81  -26.064 1.469   1   27.76  ? 178 TYR B CE1 1 
ATOM   4597 C CE2 . TYR C 1 8   ? -18.095 -26.28  -0.195  1   27.58  ? 178 TYR B CE2 1 
ATOM   4598 C CZ  . TYR C 1 8   ? -18.673 -26.686 0.992   1   28.88  ? 178 TYR B CZ  1 
ATOM   4599 O OH  . TYR C 1 8   ? -18.136 -27.725 1.694   1   32.32  ? 178 TYR B OH  1 
ATOM   4600 N N   . HIS C 1 9   ? -22.427 -22.287 -3.984  1   38.35  ? 179 HIS B N   1 
ATOM   4601 C CA  . HIS C 1 9   ? -22.993 -21.04  -4.497  1   38.14  ? 179 HIS B CA  1 
ATOM   4602 C C   . HIS C 1 9   ? -24.405 -20.801 -3.963  1   36.84  ? 179 HIS B C   1 
ATOM   4603 O O   . HIS C 1 9   ? -24.709 -19.668 -3.615  1   37.4   ? 179 HIS B O   1 
ATOM   4604 C CB  . HIS C 1 9   ? -22.833 -20.848 -6.016  1   45.8   ? 179 HIS B CB  1 
ATOM   4605 C CG  . HIS C 1 9   ? -23.764 -21.63  -6.883  1   61.04  ? 179 HIS B CG  1 
ATOM   4606 N ND1 . HIS C 1 9   ? -23.72  -23.005 -7.042  1   66.61  ? 179 HIS B ND1 1 
ATOM   4607 C CD2 . HIS C 1 9   ? -24.788 -21.215 -7.644  1   64.86  ? 179 HIS B CD2 1 
ATOM   4608 C CE1 . HIS C 1 9   ? -24.691 -23.398 -7.867  1   64.43  ? 179 HIS B CE1 1 
ATOM   4609 N NE2 . HIS C 1 9   ? -25.354 -22.325 -8.242  1   68.84  ? 179 HIS B NE2 1 
ATOM   4610 N N   . GLU C 1 10  ? -25.267 -21.832 -3.908  1   36.39  ? 180 GLU B N   1 
ATOM   4611 C CA  . GLU C 1 10  ? -26.624 -21.619 -3.428  1   36.05  ? 180 GLU B CA  1 
ATOM   4612 C C   . GLU C 1 10  ? -26.574 -21.205 -1.971  1   37.62  ? 180 GLU B C   1 
ATOM   4613 O O   . GLU C 1 10  ? -27.168 -20.187 -1.616  1   39.43  ? 180 GLU B O   1 
ATOM   4614 C CB  . GLU C 1 10  ? -27.543 -22.826 -3.359  1   39.01  ? 180 GLU B CB  1 
ATOM   4615 C CG  . GLU C 1 10  ? -28.367 -23.034 -4.623  1   45.82  ? 180 GLU B CG  1 
ATOM   4616 C CD  . GLU C 1 10  ? -29.464 -24.059 -4.353  1   52.38  ? 180 GLU B CD  1 
ATOM   4617 O OE1 . GLU C 1 10  ? -30.605 -23.727 -3.922  1   49.4   ? 180 GLU B OE1 1 
ATOM   4618 O OE2 . GLU C 1 10  ? -29.109 -25.246 -4.546  1   59.39  ? 180 GLU B OE2 1 
ATOM   4619 N N   . ASP C 1 11  ? -25.876 -22.013 -1.156  1   35.59  ? 181 ASP B N   1 
ATOM   4620 C CA  . ASP C 1 11  ? -25.768 -21.757 0.271   1   32.53  ? 181 ASP B CA  1 
ATOM   4621 C C   . ASP C 1 11  ? -25.359 -20.306 0.502   1   30.82  ? 181 ASP B C   1 
ATOM   4622 O O   . ASP C 1 11  ? -26.009 -19.608 1.268   1   30.92  ? 181 ASP B O   1 
ATOM   4623 C CB  . ASP C 1 11  ? -24.811 -22.719 0.944   1   32.18  ? 181 ASP B CB  1 
ATOM   4624 C CG  . ASP C 1 11  ? -25.424 -24.066 1.228   1   33.97  ? 181 ASP B CG  1 
ATOM   4625 O OD1 . ASP C 1 11  ? -26.646 -24.149 1.042   1   35.71  ? 181 ASP B OD1 1 
ATOM   4626 O OD2 . ASP C 1 11  ? -24.679 -24.994 1.619   1   36.06  ? 181 ASP B OD2 1 
ATOM   4627 N N   . ILE C 1 12  ? -24.297 -19.867 -0.18   1   28.48  ? 182 ILE B N   1 
ATOM   4628 C CA  . ILE C 1 12  ? -23.79  -18.52  -0.032  1   29.13  ? 182 ILE B CA  1 
ATOM   4629 C C   . ILE C 1 12  ? -24.858 -17.514 -0.455  1   31.45  ? 182 ILE B C   1 
ATOM   4630 O O   . ILE C 1 12  ? -25.063 -16.515 0.228   1   31.64  ? 182 ILE B O   1 
ATOM   4631 C CB  . ILE C 1 12  ? -22.483 -18.346 -0.817  1   28.32  ? 182 ILE B CB  1 
ATOM   4632 C CG1 . ILE C 1 12  ? -21.401 -19.211 -0.192  1   30.22  ? 182 ILE B CG1 1 
ATOM   4633 C CG2 . ILE C 1 12  ? -22.067 -16.873 -0.896  1   25.55  ? 182 ILE B CG2 1 
ATOM   4634 C CD1 . ILE C 1 12  ? -20.197 -19.407 -1.09   1   31.1   ? 182 ILE B CD1 1 
ATOM   4635 N N   . HIS C 1 13  ? -25.524 -17.761 -1.589  1   31.46  ? 183 HIS B N   1 
ATOM   4636 C CA  . HIS C 1 13  ? -26.472 -16.8   -2.125  1   30.66  ? 183 HIS B CA  1 
ATOM   4637 C C   . HIS C 1 13  ? -27.65  -16.642 -1.157  1   36.02  ? 183 HIS B C   1 
ATOM   4638 O O   . HIS C 1 13  ? -28.017 -15.527 -0.775  1   37.71  ? 183 HIS B O   1 
ATOM   4639 C CB  . HIS C 1 13  ? -26.925 -17.249 -3.509  1   28.86  ? 183 HIS B CB  1 
ATOM   4640 C CG  . HIS C 1 13  ? -28.024 -16.408 -4.015  1   27.42  ? 183 HIS B CG  1 
ATOM   4641 N ND1 . HIS C 1 13  ? -27.751 -15.146 -4.472  1   27.95  ? 183 HIS B ND1 1 
ATOM   4642 C CD2 . HIS C 1 13  ? -29.334 -16.551 -4.111  1   28.01  ? 183 HIS B CD2 1 
ATOM   4643 C CE1 . HIS C 1 13  ? -28.879 -14.542 -4.832  1   26.97  ? 183 HIS B CE1 1 
ATOM   4644 N NE2 . HIS C 1 13  ? -29.852 -15.375 -4.62   1   27.37  ? 183 HIS B NE2 1 
ATOM   4645 N N   . THR C 1 14  ? -28.251 -17.774 -0.762  1   37.12  ? 184 THR B N   1 
ATOM   4646 C CA  . THR C 1 14  ? -29.277 -17.797 0.271   1   35.59  ? 184 THR B CA  1 
ATOM   4647 C C   . THR C 1 14  ? -28.813 -17.011 1.491   1   34.99  ? 184 THR B C   1 
ATOM   4648 O O   . THR C 1 14  ? -29.607 -16.25  2.023   1   38.76  ? 184 THR B O   1 
ATOM   4649 C CB  . THR C 1 14  ? -29.627 -19.232 0.668   1   35     ? 184 THR B CB  1 
ATOM   4650 O OG1 . THR C 1 14  ? -30.116 -19.814 -0.532  1   36.5   ? 184 THR B OG1 1 
ATOM   4651 C CG2 . THR C 1 14  ? -30.695 -19.312 1.74    1   33.48  ? 184 THR B CG2 1 
ATOM   4652 N N   . TYR C 1 15  ? -27.554 -17.208 1.927   1   31.75  ? 185 TYR B N   1 
ATOM   4653 C CA  . TYR C 1 15  ? -27.03  -16.599 3.145   1   28.96  ? 185 TYR B CA  1 
ATOM   4654 C C   . TYR C 1 15  ? -26.9   -15.083 2.965   1   26.69  ? 185 TYR B C   1 
ATOM   4655 O O   . TYR C 1 15  ? -27.274 -14.31  3.845   1   25     ? 185 TYR B O   1 
ATOM   4656 C CB  . TYR C 1 15  ? -25.697 -17.228 3.558   1   29.6   ? 185 TYR B CB  1 
ATOM   4657 C CG  . TYR C 1 15  ? -25.047 -16.583 4.776   1   31.21  ? 185 TYR B CG  1 
ATOM   4658 C CD1 . TYR C 1 15  ? -25.73  -16.517 5.992   1   32.28  ? 185 TYR B CD1 1 
ATOM   4659 C CD2 . TYR C 1 15  ? -23.771 -16.018 4.711   1   31.06  ? 185 TYR B CD2 1 
ATOM   4660 C CE1 . TYR C 1 15  ? -25.175 -15.921 7.11    1   31.85  ? 185 TYR B CE1 1 
ATOM   4661 C CE2 . TYR C 1 15  ? -23.204 -15.409 5.823   1   32.86  ? 185 TYR B CE2 1 
ATOM   4662 C CZ  . TYR C 1 15  ? -23.916 -15.362 7.015   1   33.8   ? 185 TYR B CZ  1 
ATOM   4663 O OH  . TYR C 1 15  ? -23.405 -14.796 8.136   1   37.35  ? 185 TYR B OH  1 
ATOM   4664 N N   . LEU C 1 16  ? -26.38  -14.66  1.808   1   25.3   ? 186 LEU B N   1 
ATOM   4665 C CA  . LEU C 1 16  ? -26.256 -13.248 1.519   1   25.86  ? 186 LEU B CA  1 
ATOM   4666 C C   . LEU C 1 16  ? -27.643 -12.607 1.493   1   29.86  ? 186 LEU B C   1 
ATOM   4667 O O   . LEU C 1 16  ? -27.808 -11.445 1.896   1   31.49  ? 186 LEU B O   1 
ATOM   4668 C CB  . LEU C 1 16  ? -25.535 -13.075 0.191   1   24.95  ? 186 LEU B CB  1 
ATOM   4669 C CG  . LEU C 1 16  ? -24.039 -13.414 0.166   1   25.25  ? 186 LEU B CG  1 
ATOM   4670 C CD1 . LEU C 1 16  ? -23.509 -13.288 -1.268  1   23.87  ? 186 LEU B CD1 1 
ATOM   4671 C CD2 . LEU C 1 16  ? -23.196 -12.633 1.18    1   24.76  ? 186 LEU B CD2 1 
ATOM   4672 N N   . ARG C 1 17  ? -28.638 -13.378 1.02    1   31.87  ? 187 ARG B N   1 
ATOM   4673 C CA  . ARG C 1 17  ? -29.998 -12.889 0.849   1   32.03  ? 187 ARG B CA  1 
ATOM   4674 C C   . ARG C 1 17  ? -30.57  -12.511 2.208   1   36.01  ? 187 ARG B C   1 
ATOM   4675 O O   . ARG C 1 17  ? -31.289 -11.519 2.335   1   39.47  ? 187 ARG B O   1 
ATOM   4676 C CB  . ARG C 1 17  ? -30.888 -13.917 0.143   1   29.57  ? 187 ARG B CB  1 
ATOM   4677 C CG  . ARG C 1 17  ? -30.857 -13.801 -1.37   1   29.16  ? 187 ARG B CG  1 
ATOM   4678 C CD  . ARG C 1 17  ? -31.286 -12.414 -1.876  1   26.78  ? 187 ARG B CD  1 
ATOM   4679 N NE  . ARG C 1 17  ? -32.74  -12.259 -1.801  1   25.36  ? 187 ARG B NE  1 
ATOM   4680 C CZ  . ARG C 1 17  ? -33.583 -12.795 -2.661  1   25.6   ? 187 ARG B CZ  1 
ATOM   4681 N NH1 . ARG C 1 17  ? -33.134 -13.283 -3.804  1   28.03  ? 187 ARG B NH1 1 
ATOM   4682 N NH2 . ARG C 1 17  ? -34.875 -12.801 -2.414  1   24.65  ? 187 ARG B NH2 1 
ATOM   4683 N N   . GLU C 1 18  ? -30.235 -13.321 3.216   1   36.18  ? 188 GLU B N   1 
ATOM   4684 C CA  . GLU C 1 18  ? -30.731 -13.095 4.557   1   37.12  ? 188 GLU B CA  1 
ATOM   4685 C C   . GLU C 1 18  ? -29.935 -11.951 5.188   1   36.42  ? 188 GLU B C   1 
ATOM   4686 O O   . GLU C 1 18  ? -30.506 -11.085 5.84    1   36.63  ? 188 GLU B O   1 
ATOM   4687 C CB  . GLU C 1 18  ? -30.723 -14.444 5.275   1   39.73  ? 188 GLU B CB  1 
ATOM   4688 C CG  . GLU C 1 18  ? -30.876 -14.347 6.786   1   45.96  ? 188 GLU B CG  1 
ATOM   4689 C CD  . GLU C 1 18  ? -30.429 -15.636 7.463   1   50.15  ? 188 GLU B CD  1 
ATOM   4690 O OE1 . GLU C 1 18  ? -29.856 -16.494 6.746   1   47.97  ? 188 GLU B OE1 1 
ATOM   4691 O OE2 . GLU C 1 18  ? -30.673 -15.796 8.689   1   51.82  ? 188 GLU B OE2 1 
ATOM   4692 N N   . MET C 1 19  ? -28.621 -11.913 4.953   1   34.66  ? 189 MET B N   1 
ATOM   4693 C CA  . MET C 1 19  ? -27.787 -10.947 5.644   1   36.27  ? 189 MET B CA  1 
ATOM   4694 C C   . MET C 1 19  ? -28.029 -9.535  5.134   1   37.43  ? 189 MET B C   1 
ATOM   4695 O O   . MET C 1 19  ? -27.805 -8.592  5.889   1   39.18  ? 189 MET B O   1 
ATOM   4696 C CB  . MET C 1 19  ? -26.297 -11.266 5.511   1   38.11  ? 189 MET B CB  1 
ATOM   4697 C CG  . MET C 1 19  ? -25.846 -12.43  6.366   1   45.02  ? 189 MET B CG  1 
ATOM   4698 S SD  . MET C 1 19  ? -26.558 -12.55  8.024   1   55.19  ? 189 MET B SD  1 
ATOM   4699 C CE  . MET C 1 19  ? -25.251 -11.841 9.036   1   60.32  ? 189 MET B CE  1 
ATOM   4700 N N   . GLU C 1 20  ? -28.439 -9.392  3.861   1   34.75  ? 190 GLU B N   1 
ATOM   4701 C CA  . GLU C 1 20  ? -28.623 -8.054  3.328   1   32.3   ? 190 GLU B CA  1 
ATOM   4702 C C   . GLU C 1 20  ? -29.779 -7.38   4.058   1   33.27  ? 190 GLU B C   1 
ATOM   4703 O O   . GLU C 1 20  ? -29.791 -6.17   4.245   1   33.51  ? 190 GLU B O   1 
ATOM   4704 C CB  . GLU C 1 20  ? -28.745 -8.031  1.812   1   30.7   ? 190 GLU B CB  1 
ATOM   4705 C CG  . GLU C 1 20  ? -30     -8.713  1.288   1   33.84  ? 190 GLU B CG  1 
ATOM   4706 C CD  . GLU C 1 20  ? -30.177 -8.528  -0.216  1   34.48  ? 190 GLU B CD  1 
ATOM   4707 O OE1 . GLU C 1 20  ? -29.391 -7.766  -0.794  1   34.01  ? 190 GLU B OE1 1 
ATOM   4708 O OE2 . GLU C 1 20  ? -31.078 -9.15   -0.815  1   35.08  ? 190 GLU B OE2 1 
ATOM   4709 N N   . VAL C 1 21  ? -30.721 -8.197  4.523   1   35.06  ? 191 VAL B N   1 
ATOM   4710 C CA  . VAL C 1 21  ? -31.879 -7.724  5.26    1   34.88  ? 191 VAL B CA  1 
ATOM   4711 C C   . VAL C 1 21  ? -31.481 -7.312  6.673   1   38.77  ? 191 VAL B C   1 
ATOM   4712 O O   . VAL C 1 21  ? -31.956 -6.294  7.167   1   43.31  ? 191 VAL B O   1 
ATOM   4713 C CB  . VAL C 1 21  ? -32.987 -8.784  5.26    1   32.06  ? 191 VAL B CB  1 
ATOM   4714 C CG1 . VAL C 1 21  ? -34.212 -8.303  6.007   1   31.7   ? 191 VAL B CG1 1 
ATOM   4715 C CG2 . VAL C 1 21  ? -33.365 -9.119  3.83    1   32.28  ? 191 VAL B CG2 1 
ATOM   4716 N N   . LYS C 1 22  ? -30.589 -8.077  7.306   1   41.66  ? 192 LYS B N   1 
ATOM   4717 C CA  . LYS C 1 22  ? -30.061 -7.705  8.613   1   46.97  ? 192 LYS B CA  1 
ATOM   4718 C C   . LYS C 1 22  ? -29.19  -6.451  8.498   1   46.8   ? 192 LYS B C   1 
ATOM   4719 O O   . LYS C 1 22  ? -29.255 -5.582  9.36    1   51.06  ? 192 LYS B O   1 
ATOM   4720 C CB  . LYS C 1 22  ? -29.316 -8.861  9.296   1   50.32  ? 192 LYS B CB  1 
ATOM   4721 C CG  . LYS C 1 22  ? -30.095 -10.176 9.441   1   60.13  ? 192 LYS B CG  1 
ATOM   4722 C CD  . LYS C 1 22  ? -29.408 -11.196 10.352  1   76.39  ? 192 LYS B CD  1 
ATOM   4723 C CE  . LYS C 1 22  ? -29.576 -12.668 10.041  1   80.47  ? 192 LYS B CE  1 
ATOM   4724 N NZ  . LYS C 1 22  ? -30.869 -13.283 10.371  1   78.7   ? 192 LYS B NZ  1 
ATOM   4725 N N   . CYS C 1 23  ? -28.366 -6.373  7.457   1   44.01  ? 193 CYS B N   1 
ATOM   4726 C CA  . CYS C 1 23  ? -27.401 -5.254  7.334   1   43.74  ? 193 CYS B CA  1 
ATOM   4727 C C   . CYS C 1 23  ? -28.024 -4.096  6.559   1   44.92  ? 193 CYS B C   1 
ATOM   4728 O O   . CYS C 1 23  ? -27.259 -3.333  5.957   1   47.43  ? 193 CYS B O   1 
ATOM   4729 C CB  . CYS C 1 23  ? -26.151 -5.72   6.601   1   42.56  ? 193 CYS B CB  1 
ATOM   4730 S SG  . CYS C 1 23  ? -25.003 -6.689  7.611   1   56.13  ? 193 CYS B SG  1 
ATOM   4731 N N   . LYS C 1 24  ? -29.347 -3.95   6.601   1   41.91  ? 194 LYS B N   1 
ATOM   4732 C CA  . LYS C 1 24  ? -29.986 -2.93   5.79    1   43.33  ? 194 LYS B CA  1 
ATOM   4733 C C   . LYS C 1 24  ? -29.966 -1.61   6.553   1   43.53  ? 194 LYS B C   1 
ATOM   4734 O O   . LYS C 1 24  ? -30.297 -1.582  7.732   1   46.22  ? 194 LYS B O   1 
ATOM   4735 C CB  . LYS C 1 24  ? -31.441 -3.274  5.452   1   48.27  ? 194 LYS B CB  1 
ATOM   4736 C CG  . LYS C 1 24  ? -32.076 -2.312  4.457   1   52.77  ? 194 LYS B CG  1 
ATOM   4737 C CD  . LYS C 1 24  ? -33.542 -2.604  4.157   1   63.39  ? 194 LYS B CD  1 
ATOM   4738 C CE  . LYS C 1 24  ? -34.011 -1.815  2.948   1   77.06  ? 194 LYS B CE  1 
ATOM   4739 N NZ  . LYS C 1 24  ? -35.439 -2.002  2.657   1   79.35  ? 194 LYS B NZ  1 
ATOM   4740 N N   . PRO C 1 25  ? -29.557 -0.485  5.932   1   40.13  ? 195 PRO B N   1 
ATOM   4741 C CA  . PRO C 1 25  ? -29.741 0.827   6.546   1   39.03  ? 195 PRO B CA  1 
ATOM   4742 C C   . PRO C 1 25  ? -31.204 1.182   6.782   1   39.98  ? 195 PRO B C   1 
ATOM   4743 O O   . PRO C 1 25  ? -32.106 0.558   6.225   1   43.29  ? 195 PRO B O   1 
ATOM   4744 C CB  . PRO C 1 25  ? -29.102 1.779   5.518   1   40.57  ? 195 PRO B CB  1 
ATOM   4745 C CG  . PRO C 1 25  ? -28.128 0.927   4.732   1   38.39  ? 195 PRO B CG  1 
ATOM   4746 C CD  . PRO C 1 25  ? -28.798 -0.429  4.674   1   40.32  ? 195 PRO B CD  1 
ATOM   4747 N N   . LYS C 1 26  ? -31.421 2.212   7.609   1   39.83  ? 196 LYS B N   1 
ATOM   4748 C CA  . LYS C 1 26  ? -32.737 2.786   7.808   1   40.48  ? 196 LYS B CA  1 
ATOM   4749 C C   . LYS C 1 26  ? -33.046 3.624   6.566   1   41.28  ? 196 LYS B C   1 
ATOM   4750 O O   . LYS C 1 26  ? -32.227 4.422   6.135   1   39.49  ? 196 LYS B O   1 
ATOM   4751 C CB  . LYS C 1 26  ? -32.667 3.527   9.144   1   44.14  ? 196 LYS B CB  1 
ATOM   4752 C CG  . LYS C 1 26  ? -33.989 3.778   9.881   1   54.2   ? 196 LYS B CG  1 
ATOM   4753 C CD  . LYS C 1 26  ? -33.937 4.577   11.197  1   58.19  ? 196 LYS B CD  1 
ATOM   4754 C CE  . LYS C 1 26  ? -33.931 6.092   11.071  1   58.82  ? 196 LYS B CE  1 
ATOM   4755 N NZ  . LYS C 1 26  ? -33.74  6.779   12.354  1   59.33  ? 196 LYS B NZ  1 
ATOM   4756 N N   . VAL C 1 27  ? -34.22  3.484   5.964   1   44.24  ? 197 VAL B N   1 
ATOM   4757 C CA  . VAL C 1 27  ? -34.461 4.181   4.662   1   47.19  ? 197 VAL B CA  1 
ATOM   4758 C C   . VAL C 1 27  ? -34.561 5.701   4.857   1   52.67  ? 197 VAL B C   1 
ATOM   4759 O O   . VAL C 1 27  ? -33.946 6.431   4.067   1   57.13  ? 197 VAL B O   1 
ATOM   4760 C CB  . VAL C 1 27  ? -35.681 3.628   3.901   1   47.6   ? 197 VAL B CB  1 
ATOM   4761 C CG1 . VAL C 1 27  ? -35.778 4.198   2.493   1   41.94  ? 197 VAL B CG1 1 
ATOM   4762 C CG2 . VAL C 1 27  ? -35.668 2.106   3.858   1   48.5   ? 197 VAL B CG2 1 
ATOM   4763 N N   . GLY C 1 28  ? -35.309 6.163   5.848   1   54.66  ? 198 GLY B N   1 
ATOM   4764 C CA  . GLY C 1 28  ? -35.489 7.617   6.005   1   62.73  ? 198 GLY B CA  1 
ATOM   4765 C C   . GLY C 1 28  ? -34.59  8.162   7.086   1   66.36  ? 198 GLY B C   1 
ATOM   4766 O O   . GLY C 1 28  ? -35.105 8.851   7.981   1   68.28  ? 198 GLY B O   1 
ATOM   4767 N N   . TYR C 1 29  ? -33.39  7.996   7.13    1   59     ? 199 TYR B N   1 
ATOM   4768 C CA  . TYR C 1 29  ? -32.518 8.441   8.242   1   52.83  ? 199 TYR B CA  1 
ATOM   4769 C C   . TYR C 1 29  ? -32.033 9.845   7.993   1   53.7   ? 199 TYR B C   1 
ATOM   4770 O O   . TYR C 1 29  ? -31.639 10.514  8.957   1   58     ? 199 TYR B O   1 
ATOM   4771 C CB  . TYR C 1 29  ? -31.401 7.39    8.313   1   44.85  ? 199 TYR B CB  1 
ATOM   4772 C CG  . TYR C 1 29  ? -30.168 7.501   7.424   1   42.16  ? 199 TYR B CG  1 
ATOM   4773 C CD1 . TYR C 1 29  ? -29.299 8.582   7.505   1   42.26  ? 199 TYR B CD1 1 
ATOM   4774 C CD2 . TYR C 1 29  ? -29.833 6.48    6.547   1   40.19  ? 199 TYR B CD2 1 
ATOM   4775 C CE1 . TYR C 1 29  ? -28.178 8.675   6.701   1   40.31  ? 199 TYR B CE1 1 
ATOM   4776 C CE2 . TYR C 1 29  ? -28.704 6.55    5.749   1   38.71  ? 199 TYR B CE2 1 
ATOM   4777 C CZ  . TYR C 1 29  ? -27.874 7.652   5.826   1   38.56  ? 199 TYR B CZ  1 
ATOM   4778 O OH  . TYR C 1 29  ? -26.761 7.739   5.045   1   35.87  ? 199 TYR B OH  1 
ATOM   4779 N N   . MET C 1 30  ? -32.045 10.276  6.736   1   48.11  ? 200 MET B N   1 
ATOM   4780 C CA  . MET C 1 30  ? -31.5   11.621  6.439   1   49.01  ? 200 MET B CA  1 
ATOM   4781 C C   . MET C 1 30  ? -32.491 12.653  6.98    1   51.05  ? 200 MET B C   1 
ATOM   4782 O O   . MET C 1 30  ? -32.067 13.756  7.348   1   53.73  ? 200 MET B O   1 
ATOM   4783 C CB  . MET C 1 30  ? -31.253 11.803  4.94    1   46.42  ? 200 MET B CB  1 
ATOM   4784 C CG  . MET C 1 30  ? -30.078 12.69   4.613   1   45.9   ? 200 MET B CG  1 
ATOM   4785 S SD  . MET C 1 30  ? -28.595 12.255  5.537   1   45.36  ? 200 MET B SD  1 
ATOM   4786 C CE  . MET C 1 30  ? -27.528 11.686  4.211   1   42.24  ? 200 MET B CE  1 
ATOM   4787 N N   . LYS C 1 31  ? -33.77  12.262  7.054   1   53.23  ? 201 LYS B N   1 
ATOM   4788 C CA  . LYS C 1 31  ? -34.811 13.165  7.588   1   57.49  ? 201 LYS B CA  1 
ATOM   4789 C C   . LYS C 1 31  ? -34.605 13.333  9.096   1   58.72  ? 201 LYS B C   1 
ATOM   4790 O O   . LYS C 1 31  ? -34.991 14.378  9.633   1   61.34  ? 201 LYS B O   1 
ATOM   4791 C CB  . LYS C 1 31  ? -36.165 12.543  7.255   1   61.79  ? 201 LYS B CB  1 
ATOM   4792 C CG  . LYS C 1 31  ? -36.263 11.909  5.88    1   68.13  ? 201 LYS B CG  1 
ATOM   4793 C CD  . LYS C 1 31  ? -37.681 11.459  5.553   1   77.32  ? 201 LYS B CD  1 
ATOM   4794 C CE  . LYS C 1 31  ? -38.406 10.945  6.755   1   81.23  ? 201 LYS B CE  1 
ATOM   4795 N NZ  . LYS C 1 31  ? -38.512 9.483   6.75    1   81.8   ? 201 LYS B NZ  1 
ATOM   4796 N N   . LYS C 1 32  ? -34     12.357  9.739   1   60.09  ? 202 LYS B N   1 
ATOM   4797 C CA  . LYS C 1 32  ? -33.749 12.404  11.203  1   61.65  ? 202 LYS B CA  1 
ATOM   4798 C C   . LYS C 1 32  ? -32.317 12.876  11.433  1   57.07  ? 202 LYS B C   1 
ATOM   4799 O O   . LYS C 1 32  ? -31.852 12.804  12.579  1   56.84  ? 202 LYS B O   1 
ATOM   4800 C CB  . LYS C 1 32  ? -33.993 11.031  11.831  1   66.85  ? 202 LYS B CB  1 
ATOM   4801 C CG  . LYS C 1 32  ? -34.896 10.117  11.026  1   72.43  ? 202 LYS B CG  1 
ATOM   4802 C CD  . LYS C 1 32  ? -36.333 10.106  11.529  1   80.9   ? 202 LYS B CD  1 
ATOM   4803 C CE  . LYS C 1 32  ? -37.016 8.812   11.234  1   82.37  ? 202 LYS B CE  1 
ATOM   4804 N NZ  . LYS C 1 32  ? -37.241 8.641   9.798   1   81.14  ? 202 LYS B NZ  1 
ATOM   4805 N N   . GLN C 1 33  ? -31.638 13.273  10.367  1   51.66  ? 203 GLN B N   1 
ATOM   4806 C CA  . GLN C 1 33  ? -30.309 13.848  10.459  1   48.36  ? 203 GLN B CA  1 
ATOM   4807 C C   . GLN C 1 33  ? -30.48  15.357  10.386  1   48.96  ? 203 GLN B C   1 
ATOM   4808 O O   . GLN C 1 33  ? -30.729 15.914  9.312   1   48.78  ? 203 GLN B O   1 
ATOM   4809 C CB  . GLN C 1 33  ? -29.405 13.31   9.35    1   46.41  ? 203 GLN B CB  1 
ATOM   4810 C CG  . GLN C 1 33  ? -28.78  11.948  9.627   1   44.89  ? 203 GLN B CG  1 
ATOM   4811 C CD  . GLN C 1 33  ? -27.693 12.011  10.681  1   46.36  ? 203 GLN B CD  1 
ATOM   4812 O OE1 . GLN C 1 33  ? -27.234 13.091  11.078  1   49.39  ? 203 GLN B OE1 1 
ATOM   4813 N NE2 . GLN C 1 33  ? -27.271 10.846  11.149  1   45.09  ? 203 GLN B NE2 1 
ATOM   4814 N N   . PRO C 1 34  ? -30.422 16.044  11.547  1   50.61  ? 204 PRO B N   1 
ATOM   4815 C CA  . PRO C 1 34  ? -30.614 17.488  11.603  1   52.14  ? 204 PRO B CA  1 
ATOM   4816 C C   . PRO C 1 34  ? -29.652 18.303  10.74   1   51.65  ? 204 PRO B C   1 
ATOM   4817 O O   . PRO C 1 34  ? -30.021 19.352  10.245  1   54.2   ? 204 PRO B O   1 
ATOM   4818 C CB  . PRO C 1 34  ? -30.463 17.812  13.1    1   53.19  ? 204 PRO B CB  1 
ATOM   4819 C CG  . PRO C 1 34  ? -29.655 16.681  13.647  1   51.91  ? 204 PRO B CG  1 
ATOM   4820 C CD  . PRO C 1 34  ? -30.168 15.477  12.882  1   50.83  ? 204 PRO B CD  1 
ATOM   4821 N N   . ASP C 1 35  ? -28.424 17.825  10.541  1   49.92  ? 205 ASP B N   1 
ATOM   4822 C CA  . ASP C 1 35  ? -27.399 18.71   10.012  1   49.39  ? 205 ASP B CA  1 
ATOM   4823 C C   . ASP C 1 35  ? -26.801 18.212  8.7     1   47.26  ? 205 ASP B C   1 
ATOM   4824 O O   . ASP C 1 35  ? -25.901 18.854  8.162   1   48.19  ? 205 ASP B O   1 
ATOM   4825 C CB  . ASP C 1 35  ? -26.246 18.84   10.986  1   49.22  ? 205 ASP B CB  1 
ATOM   4826 C CG  . ASP C 1 35  ? -25.46  20.115  10.782  1   50.04  ? 205 ASP B CG  1 
ATOM   4827 O OD1 . ASP C 1 35  ? -26.108 21.188  10.753  1   51.82  ? 205 ASP B OD1 1 
ATOM   4828 O OD2 . ASP C 1 35  ? -24.234 20.008  10.65   1   49.3   ? 205 ASP B OD2 1 
ATOM   4829 N N   . ILE C 1 36  ? -27.251 17.048  8.231   1   44.38  ? 206 ILE B N   1 
ATOM   4830 C CA  . ILE C 1 36  ? -26.765 16.55   6.965   1   42.06  ? 206 ILE B CA  1 
ATOM   4831 C C   . ILE C 1 36  ? -27.94  16.137  6.084   1   41.99  ? 206 ILE B C   1 
ATOM   4832 O O   . ILE C 1 36  ? -29.074 15.964  6.549   1   42.3   ? 206 ILE B O   1 
ATOM   4833 C CB  . ILE C 1 36  ? -25.706 15.459  7.162   1   40.66  ? 206 ILE B CB  1 
ATOM   4834 C CG1 . ILE C 1 36  ? -26.257 14.198  7.848   1   39.1   ? 206 ILE B CG1 1 
ATOM   4835 C CG2 . ILE C 1 36  ? -24.504 16.034  7.907   1   41.8   ? 206 ILE B CG2 1 
ATOM   4836 C CD1 . ILE C 1 36  ? -25.353 12.99   7.704   1   36.12  ? 206 ILE B CD1 1 
ATOM   4837 N N   . THR C 1 37  ? -27.626 16.027  4.787   1   41.87  ? 207 THR B N   1 
ATOM   4838 C CA  . THR C 1 37  ? -28.602 15.929  3.711   1   42.51  ? 207 THR B CA  1 
ATOM   4839 C C   . THR C 1 37  ? -28.039 14.981  2.66    1   41.56  ? 207 THR B C   1 
ATOM   4840 O O   . THR C 1 37  ? -26.823 14.796  2.607   1   41.17  ? 207 THR B O   1 
ATOM   4841 C CB  . THR C 1 37  ? -28.839 17.306  3.082   1   43.61  ? 207 THR B CB  1 
ATOM   4842 O OG1 . THR C 1 37  ? -27.565 17.737  2.619   1   44.98  ? 207 THR B OG1 1 
ATOM   4843 C CG2 . THR C 1 37  ? -29.383 18.346  4.041   1   44.86  ? 207 THR B CG2 1 
ATOM   4844 N N   . ASN C 1 38  ? -28.926 14.431  1.815   1   41.91  ? 208 ASN B N   1 
ATOM   4845 C CA  . ASN C 1 38  ? -28.559 13.389  0.866   1   41.18  ? 208 ASN B CA  1 
ATOM   4846 C C   . ASN C 1 38  ? -27.507 13.909  -0.098  1   41.71  ? 208 ASN B C   1 
ATOM   4847 O O   . ASN C 1 38  ? -26.709 13.133  -0.621  1   39.14  ? 208 ASN B O   1 
ATOM   4848 C CB  . ASN C 1 38  ? -29.721 12.93   -0.003  1   41.76  ? 208 ASN B CB  1 
ATOM   4849 C CG  . ASN C 1 38  ? -30.791 12.217  0.785   1   44.13  ? 208 ASN B CG  1 
ATOM   4850 O OD1 . ASN C 1 38  ? -30.498 11.269  1.528   1   43.81  ? 208 ASN B OD1 1 
ATOM   4851 N ND2 . ASN C 1 38  ? -32.035 12.65   0.631   1   46     ? 208 ASN B ND2 1 
ATOM   4852 N N   . SER C 1 39  ? -27.572 15.219  -0.362  1   44.38  ? 209 SER B N   1 
ATOM   4853 C CA  . SER C 1 39  ? -26.587 15.907  -1.178  1   44.39  ? 209 SER B CA  1 
ATOM   4854 C C   . SER C 1 39  ? -25.198 15.834  -0.528  1   43.97  ? 209 SER B C   1 
ATOM   4855 O O   . SER C 1 39  ? -24.228 15.471  -1.207  1   41.6   ? 209 SER B O   1 
ATOM   4856 C CB  . SER C 1 39  ? -27.029 17.314  -1.431  1   45.92  ? 209 SER B CB  1 
ATOM   4857 O OG  . SER C 1 39  ? -25.883 18.115  -1.653  1   46.96  ? 209 SER B OG  1 
ATOM   4858 N N   . MET C 1 40  ? -25.108 16.166  0.762   1   43.38  ? 210 MET B N   1 
ATOM   4859 C CA  . MET C 1 40  ? -23.806 16.058  1.471   1   42.27  ? 210 MET B CA  1 
ATOM   4860 C C   . MET C 1 40  ? -23.288 14.618  1.338   1   40.33  ? 210 MET B C   1 
ATOM   4861 O O   . MET C 1 40  ? -22.083 14.442  1.052   1   41.15  ? 210 MET B O   1 
ATOM   4862 C CB  . MET C 1 40  ? -23.951 16.429  2.951   1   42.36  ? 210 MET B CB  1 
ATOM   4863 C CG  . MET C 1 40  ? -24.16  17.911  3.18    1   46.37  ? 210 MET B CG  1 
ATOM   4864 S SD  . MET C 1 40  ? -24.163 18.374  4.923   1   49.26  ? 210 MET B SD  1 
ATOM   4865 C CE  . MET C 1 40  ? -25.481 19.597  4.905   1   48.67  ? 210 MET B CE  1 
ATOM   4866 N N   . ARG C 1 41  ? -24.17  13.632  1.529   1   37.54  ? 211 ARG B N   1 
ATOM   4867 C CA  . ARG C 1 41  ? -23.767 12.207  1.407   1   35.13  ? 211 ARG B CA  1 
ATOM   4868 C C   . ARG C 1 41  ? -23.2   11.964  0.001   1   34.36  ? 211 ARG B C   1 
ATOM   4869 O O   . ARG C 1 41  ? -22.092 11.398  -0.101  1   33.35  ? 211 ARG B O   1 
ATOM   4870 C CB  . ARG C 1 41  ? -24.955 11.273  1.655   1   34.38  ? 211 ARG B CB  1 
ATOM   4871 C CG  . ARG C 1 41  ? -24.592 9.795   1.636   1   32.46  ? 211 ARG B CG  1 
ATOM   4872 C CD  . ARG C 1 41  ? -25.805 8.909   1.869   1   33.67  ? 211 ARG B CD  1 
ATOM   4873 N NE  . ARG C 1 41  ? -25.566 7.517   1.472   1   34.36  ? 211 ARG B NE  1 
ATOM   4874 C CZ  . ARG C 1 41  ? -26.026 6.963   0.358   1   33.99  ? 211 ARG B CZ  1 
ATOM   4875 N NH1 . ARG C 1 41  ? -25.914 7.602   -0.792  1   34.4   ? 211 ARG B NH1 1 
ATOM   4876 N NH2 . ARG C 1 41  ? -26.597 5.774   0.397   1   32.1   ? 211 ARG B NH2 1 
ATOM   4877 N N   . ALA C 1 42  ? -23.941 12.369  -1.034  1   35.19  ? 212 ALA B N   1 
ATOM   4878 C CA  . ALA C 1 42  ? -23.466 12.194  -2.427  1   34.86  ? 212 ALA B CA  1 
ATOM   4879 C C   . ALA C 1 42  ? -21.997 12.607  -2.518  1   35.42  ? 212 ALA B C   1 
ATOM   4880 O O   . ALA C 1 42  ? -21.16  11.784  -2.95   1   34.17  ? 212 ALA B O   1 
ATOM   4881 C CB  . ALA C 1 42  ? -24.324 13.007  -3.368  1   36.06  ? 212 ALA B CB  1 
ATOM   4882 N N   . ILE C 1 43  ? -21.698 13.845  -2.12   1   36.59  ? 213 ILE B N   1 
ATOM   4883 C CA  . ILE C 1 43  ? -20.297 14.355  -2.171  1   37.48  ? 213 ILE B CA  1 
ATOM   4884 C C   . ILE C 1 43  ? -19.378 13.369  -1.437  1   37.07  ? 213 ILE B C   1 
ATOM   4885 O O   . ILE C 1 43  ? -18.343 12.982  -2.02   1   40.25  ? 213 ILE B O   1 
ATOM   4886 C CB  . ILE C 1 43  ? -20.211 15.758  -1.545  1   39.26  ? 213 ILE B CB  1 
ATOM   4887 C CG1 . ILE C 1 43  ? -21.316 16.675  -2.064  1   41.51  ? 213 ILE B CG1 1 
ATOM   4888 C CG2 . ILE C 1 43  ? -18.825 16.367  -1.753  1   39.53  ? 213 ILE B CG2 1 
ATOM   4889 C CD1 . ILE C 1 43  ? -21.655 17.821  -1.129  1   44.18  ? 213 ILE B CD1 1 
ATOM   4890 N N   . LEU C 1 44  ? -19.742 12.974  -0.214  1   35.49  ? 214 LEU B N   1 
ATOM   4891 C CA  . LEU C 1 44  ? -18.846 12.124  0.561   1   32.61  ? 214 LEU B CA  1 
ATOM   4892 C C   . LEU C 1 44  ? -18.568 10.819  -0.168  1   30.78  ? 214 LEU B C   1 
ATOM   4893 O O   . LEU C 1 44  ? -17.433 10.349  -0.207  1   30.8   ? 214 LEU B O   1 
ATOM   4894 C CB  . LEU C 1 44  ? -19.396 11.804  1.941   1   31.61  ? 214 LEU B CB  1 
ATOM   4895 C CG  . LEU C 1 44  ? -18.659 10.667  2.659   1   30.19  ? 214 LEU B CG  1 
ATOM   4896 C CD1 . LEU C 1 44  ? -17.358 11.164  3.276   1   30.94  ? 214 LEU B CD1 1 
ATOM   4897 C CD2 . LEU C 1 44  ? -19.526 9.998   3.705   1   29.48  ? 214 LEU B CD2 1 
ATOM   4898 N N   . VAL C 1 45  ? -19.621 10.204  -0.699  1   29.6   ? 215 VAL B N   1 
ATOM   4899 C CA  . VAL C 1 45  ? -19.419 8.923   -1.343  1   28.57  ? 215 VAL B CA  1 
ATOM   4900 C C   . VAL C 1 45  ? -18.525 9.109   -2.564  1   29.99  ? 215 VAL B C   1 
ATOM   4901 O O   . VAL C 1 45  ? -17.636 8.292   -2.806  1   29.78  ? 215 VAL B O   1 
ATOM   4902 C CB  . VAL C 1 45  ? -20.754 8.265   -1.706  1   27.31  ? 215 VAL B CB  1 
ATOM   4903 C CG1 . VAL C 1 45  ? -20.545 7.132   -2.714  1   25.7   ? 215 VAL B CG1 1 
ATOM   4904 C CG2 . VAL C 1 45  ? -21.467 7.797   -0.435  1   26.82  ? 215 VAL B CG2 1 
ATOM   4905 N N   . ASP C 1 46  ? -18.766 10.209  -3.3    1   30.98  ? 216 ASP B N   1 
ATOM   4906 C CA  . ASP C 1 46  ? -18.074 10.503  -4.543  1   31.46  ? 216 ASP B CA  1 
ATOM   4907 C C   . ASP C 1 46  ? -16.595 10.63   -4.24   1   33.55  ? 216 ASP B C   1 
ATOM   4908 O O   . ASP C 1 46  ? -15.745 10.196  -5.022  1   35.74  ? 216 ASP B O   1 
ATOM   4909 C CB  . ASP C 1 46  ? -18.539 11.813  -5.163  1   32.37  ? 216 ASP B CB  1 
ATOM   4910 C CG  . ASP C 1 46  ? -17.866 12.209  -6.472  1   32.29  ? 216 ASP B CG  1 
ATOM   4911 O OD1 . ASP C 1 46  ? -18.267 11.681  -7.534  1   32.07  ? 216 ASP B OD1 1 
ATOM   4912 O OD2 . ASP C 1 46  ? -16.923 13.011  -6.414  1   32.85  ? 216 ASP B OD2 1 
ATOM   4913 N N   . TRP C 1 47  ? -16.31  11.259  -3.102  1   34.38  ? 217 TRP B N   1 
ATOM   4914 C CA  . TRP C 1 47  ? -14.939 11.406  -2.662  1   35.41  ? 217 TRP B CA  1 
ATOM   4915 C C   . TRP C 1 47  ? -14.305 10.049  -2.399  1   36.57  ? 217 TRP B C   1 
ATOM   4916 O O   . TRP C 1 47  ? -13.141 9.852   -2.747  1   39.84  ? 217 TRP B O   1 
ATOM   4917 C CB  . TRP C 1 47  ? -14.928 12.249  -1.401  1   33.94  ? 217 TRP B CB  1 
ATOM   4918 C CG  . TRP C 1 47  ? -13.564 12.391  -0.816  1   34.69  ? 217 TRP B CG  1 
ATOM   4919 C CD1 . TRP C 1 47  ? -12.479 13.02   -1.34   1   35.89  ? 217 TRP B CD1 1 
ATOM   4920 C CD2 . TRP C 1 47  ? -13.187 11.944  0.495   1   35.98  ? 217 TRP B CD2 1 
ATOM   4921 N NE1 . TRP C 1 47  ? -11.442 13.012  -0.442  1   37.15  ? 217 TRP B NE1 1 
ATOM   4922 C CE2 . TRP C 1 47  ? -11.845 12.357  0.692   1   37.24  ? 217 TRP B CE2 1 
ATOM   4923 C CE3 . TRP C 1 47  ? -13.866 11.267  1.515   1   34.57  ? 217 TRP B CE3 1 
ATOM   4924 C CZ2 . TRP C 1 47  ? -11.157 12.077  1.867   1   37.64  ? 217 TRP B CZ2 1 
ATOM   4925 C CZ3 . TRP C 1 47  ? -13.184 11.005  2.679   1   35.49  ? 217 TRP B CZ3 1 
ATOM   4926 C CH2 . TRP C 1 47  ? -11.854 11.401  2.847   1   37.15  ? 217 TRP B CH2 1 
ATOM   4927 N N   . LEU C 1 48  ? -15.074 9.132   -1.787  1   34.8   ? 218 LEU B N   1 
ATOM   4928 C CA  . LEU C 1 48  ? -14.571 7.815   -1.447  1   33.71  ? 218 LEU B CA  1 
ATOM   4929 C C   . LEU C 1 48  ? -14.244 7.05    -2.719  1   32.43  ? 218 LEU B C   1 
ATOM   4930 O O   . LEU C 1 48  ? -13.213 6.389   -2.782  1   33.19  ? 218 LEU B O   1 
ATOM   4931 C CB  . LEU C 1 48  ? -15.563 7.061   -0.57   1   33.52  ? 218 LEU B CB  1 
ATOM   4932 C CG  . LEU C 1 48  ? -15.733 7.607   0.847   1   35.15  ? 218 LEU B CG  1 
ATOM   4933 C CD1 . LEU C 1 48  ? -16.89  6.97    1.573   1   34.28  ? 218 LEU B CD1 1 
ATOM   4934 C CD2 . LEU C 1 48  ? -14.449 7.402   1.634   1   35.8   ? 218 LEU B CD2 1 
ATOM   4935 N N   . VAL C 1 49  ? -15.123 7.153   -3.719  1   31.66  ? 219 VAL B N   1 
ATOM   4936 C CA  . VAL C 1 49  ? -14.834 6.632   -5.049  1   33.57  ? 219 VAL B CA  1 
ATOM   4937 C C   . VAL C 1 49  ? -13.439 7.092   -5.475  1   36.01  ? 219 VAL B C   1 
ATOM   4938 O O   . VAL C 1 49  ? -12.616 6.311   -5.952  1   36.08  ? 219 VAL B O   1 
ATOM   4939 C CB  . VAL C 1 49  ? -15.929 7.106   -6.028  1   33.52  ? 219 VAL B CB  1 
ATOM   4940 C CG1 . VAL C 1 49  ? -15.517 6.966   -7.487  1   31.97  ? 219 VAL B CG1 1 
ATOM   4941 C CG2 . VAL C 1 49  ? -17.244 6.375   -5.776  1   33.23  ? 219 VAL B CG2 1 
ATOM   4942 N N   . GLU C 1 50  ? -13.178 8.383   -5.259  1   39.03  ? 220 GLU B N   1 
ATOM   4943 C CA  . GLU C 1 50  ? -11.963 9.016   -5.72   1   40.68  ? 220 GLU B CA  1 
ATOM   4944 C C   . GLU C 1 50  ? -10.787 8.553   -4.875  1   42     ? 220 GLU B C   1 
ATOM   4945 O O   . GLU C 1 50  ? -9.676  8.407   -5.367  1   46.46  ? 220 GLU B O   1 
ATOM   4946 C CB  . GLU C 1 50  ? -12.138 10.517  -5.571  1   43.95  ? 220 GLU B CB  1 
ATOM   4947 C CG  . GLU C 1 50  ? -11.398 11.264  -6.671  1   51.63  ? 220 GLU B CG  1 
ATOM   4948 C CD  . GLU C 1 50  ? -11.665 12.737  -6.506  1   59.08  ? 220 GLU B CD  1 
ATOM   4949 O OE1 . GLU C 1 50  ? -11.627 13.431  -7.542  1   67.82  ? 220 GLU B OE1 1 
ATOM   4950 O OE2 . GLU C 1 50  ? -11.916 13.169  -5.36   1   61.07  ? 220 GLU B OE2 1 
ATOM   4951 N N   . VAL C 1 51  ? -11.031 8.308   -3.592  1   40.39  ? 221 VAL B N   1 
ATOM   4952 C CA  . VAL C 1 51  ? -9.973  7.794   -2.741  1   40.76  ? 221 VAL B CA  1 
ATOM   4953 C C   . VAL C 1 51  ? -9.622  6.363   -3.165  1   40.1   ? 221 VAL B C   1 
ATOM   4954 O O   . VAL C 1 51  ? -8.451  5.976   -3.143  1   38.62  ? 221 VAL B O   1 
ATOM   4955 C CB  . VAL C 1 51  ? -10.392 7.942   -1.264  1   39.22  ? 221 VAL B CB  1 
ATOM   4956 C CG1 . VAL C 1 51  ? -9.68   6.96    -0.332  1   37.88  ? 221 VAL B CG1 1 
ATOM   4957 C CG2 . VAL C 1 51  ? -10.233 9.386   -0.8    1   38.33  ? 221 VAL B CG2 1 
ATOM   4958 N N   . GLY C 1 52  ? -10.65  5.608   -3.585  1   39.51  ? 222 GLY B N   1 
ATOM   4959 C CA  . GLY C 1 52  ? -10.508 4.232   -4.032  1   38.63  ? 222 GLY B CA  1 
ATOM   4960 C C   . GLY C 1 52  ? -9.642  4.112   -5.286  1   42.26  ? 222 GLY B C   1 
ATOM   4961 O O   . GLY C 1 52  ? -8.747  3.269   -5.337  1   41.32  ? 222 GLY B O   1 
ATOM   4962 N N   . GLU C 1 53  ? -9.9    4.957   -6.299  1   45.98  ? 223 GLU B N   1 
ATOM   4963 C CA  . GLU C 1 53  ? -9.034  5.018   -7.47   1   47.15  ? 223 GLU B CA  1 
ATOM   4964 C C   . GLU C 1 53  ? -7.626  5.433   -7.061  1   44.69  ? 223 GLU B C   1 
ATOM   4965 O O   . GLU C 1 53  ? -6.663  4.871   -7.551  1   47.12  ? 223 GLU B O   1 
ATOM   4966 C CB  . GLU C 1 53  ? -9.522  5.992   -8.536  1   57.48  ? 223 GLU B CB  1 
ATOM   4967 C CG  . GLU C 1 53  ? -10.307 5.378   -9.694  1   70.8   ? 223 GLU B CG  1 
ATOM   4968 C CD  . GLU C 1 53  ? -10.29  6.244   -10.973 1   85.9   ? 223 GLU B CD  1 
ATOM   4969 O OE1 . GLU C 1 53  ? -10.872 7.364   -11.003 1   80.76  ? 223 GLU B OE1 1 
ATOM   4970 O OE2 . GLU C 1 53  ? -9.671  5.814   -11.984 1   89.68  ? 223 GLU B OE2 1 
ATOM   4971 N N   . GLU C 1 54  ? -7.509  6.42    -6.171  1   45.79  ? 224 GLU B N   1 
ATOM   4972 C CA  . GLU C 1 54  ? -6.215  6.941   -5.749  1   49.07  ? 224 GLU B CA  1 
ATOM   4973 C C   . GLU C 1 54  ? -5.358  5.869   -5.072  1   45.26  ? 224 GLU B C   1 
ATOM   4974 O O   . GLU C 1 54  ? -4.155  5.837   -5.247  1   47.75  ? 224 GLU B O   1 
ATOM   4975 C CB  . GLU C 1 54  ? -6.406  8.15    -4.832  1   56.09  ? 224 GLU B CB  1 
ATOM   4976 C CG  . GLU C 1 54  ? -5.103  8.78    -4.344  1   68.29  ? 224 GLU B CG  1 
ATOM   4977 C CD  . GLU C 1 54  ? -4.237  9.421   -5.422  1   79.25  ? 224 GLU B CD  1 
ATOM   4978 O OE1 . GLU C 1 54  ? -4.757  9.698   -6.53   1   81.82  ? 224 GLU B OE1 1 
ATOM   4979 O OE2 . GLU C 1 54  ? -3.027  9.635   -5.163  1   84.2   ? 224 GLU B OE2 1 
ATOM   4980 N N   . TYR C 1 55  ? -5.954  5.004   -4.263  1   43.12  ? 225 TYR B N   1 
ATOM   4981 C CA  . TYR C 1 55  ? -5.172  4.023   -3.529  1   42.1   ? 225 TYR B CA  1 
ATOM   4982 C C   . TYR C 1 55  ? -5.283  2.645   -4.178  1   41.76  ? 225 TYR B C   1 
ATOM   4983 O O   . TYR C 1 55  ? -4.772  1.659   -3.63   1   38.29  ? 225 TYR B O   1 
ATOM   4984 C CB  . TYR C 1 55  ? -5.55   4.096   -2.047  1   41.12  ? 225 TYR B CB  1 
ATOM   4985 C CG  . TYR C 1 55  ? -4.847  5.267   -1.389  1   44.33  ? 225 TYR B CG  1 
ATOM   4986 C CD1 . TYR C 1 55  ? -3.541  5.141   -0.929  1   46.51  ? 225 TYR B CD1 1 
ATOM   4987 C CD2 . TYR C 1 55  ? -5.457  6.511   -1.294  1   46.07  ? 225 TYR B CD2 1 
ATOM   4988 C CE1 . TYR C 1 55  ? -2.875  6.222   -0.37   1   50.04  ? 225 TYR B CE1 1 
ATOM   4989 C CE2 . TYR C 1 55  ? -4.801  7.594   -0.72   1   47.68  ? 225 TYR B CE2 1 
ATOM   4990 C CZ  . TYR C 1 55  ? -3.507  7.452   -0.251  1   48.69  ? 225 TYR B CZ  1 
ATOM   4991 O OH  . TYR C 1 55  ? -2.864  8.519   0.311   1   48.58  ? 225 TYR B OH  1 
ATOM   4992 N N   . LYS C 1 56  ? -5.906  2.604   -5.375  1   43.12  ? 226 LYS B N   1 
ATOM   4993 C CA  . LYS C 1 56  ? -6.031  1.374   -6.153  1   43.84  ? 226 LYS B CA  1 
ATOM   4994 C C   . LYS C 1 56  ? -6.63   0.289   -5.246  1   41.62  ? 226 LYS B C   1 
ATOM   4995 O O   . LYS C 1 56  ? -6      -0.737  -4.972  1   41.56  ? 226 LYS B O   1 
ATOM   4996 C CB  . LYS C 1 56  ? -4.675  0.951   -6.732  1   46.15  ? 226 LYS B CB  1 
ATOM   4997 C CG  . LYS C 1 56  ? -3.78   2.038   -7.316  1   52.58  ? 226 LYS B CG  1 
ATOM   4998 C CD  . LYS C 1 56  ? -3.986  2.302   -8.802  1   59.58  ? 226 LYS B CD  1 
ATOM   4999 C CE  . LYS C 1 56  ? -3.738  1.044   -9.605  1   63.91  ? 226 LYS B CE  1 
ATOM   5000 N NZ  . LYS C 1 56  ? -2.397  0.457   -9.448  1   60.28  ? 226 LYS B NZ  1 
ATOM   5001 N N   . LEU C 1 57  ? -7.845  0.567   -4.748  1   38.39  ? 227 LEU B N   1 
ATOM   5002 C CA  . LEU C 1 57  ? -8.58   -0.261  -3.805  1   33.98  ? 227 LEU B CA  1 
ATOM   5003 C C   . LEU C 1 57  ? -9.616  -1.062  -4.571  1   32.99  ? 227 LEU B C   1 
ATOM   5004 O O   . LEU C 1 57  ? -10.097 -0.618  -5.599  1   34.07  ? 227 LEU B O   1 
ATOM   5005 C CB  . LEU C 1 57  ? -9.294  0.588   -2.756  1   31.13  ? 227 LEU B CB  1 
ATOM   5006 C CG  . LEU C 1 57  ? -8.398  1.334   -1.763  1   31.99  ? 227 LEU B CG  1 
ATOM   5007 C CD1 . LEU C 1 57  ? -9.278  2.106   -0.78   1   32.32  ? 227 LEU B CD1 1 
ATOM   5008 C CD2 . LEU C 1 57  ? -7.423  0.421   -1.045  1   30.66  ? 227 LEU B CD2 1 
ATOM   5009 N N   . GLN C 1 58  ? -9.966  -2.225  -4.029  1   31.68  ? 228 GLN B N   1 
ATOM   5010 C CA  . GLN C 1 58  ? -10.983 -3.064  -4.611  1   31.5   ? 228 GLN B CA  1 
ATOM   5011 C C   . GLN C 1 58  ? -12.273 -2.269  -4.64   1   33.24  ? 228 GLN B C   1 
ATOM   5012 O O   . GLN C 1 58  ? -12.51  -1.445  -3.758  1   35.18  ? 228 GLN B O   1 
ATOM   5013 C CB  . GLN C 1 58  ? -11.102 -4.314  -3.741  1   31.64  ? 228 GLN B CB  1 
ATOM   5014 C CG  . GLN C 1 58  ? -9.898  -5.232  -3.892  1   33.8   ? 228 GLN B CG  1 
ATOM   5015 C CD  . GLN C 1 58  ? -9.696  -5.645  -5.341  1   34.73  ? 228 GLN B CD  1 
ATOM   5016 O OE1 . GLN C 1 58  ? -10.603 -6.184  -5.991  1   34.42  ? 228 GLN B OE1 1 
ATOM   5017 N NE2 . GLN C 1 58  ? -8.527  -5.35   -5.889  1   34.15  ? 228 GLN B NE2 1 
ATOM   5018 N N   . ASN C 1 59  ? -13.107 -2.548  -5.648  1   35.83  ? 229 ASN B N   1 
ATOM   5019 C CA  . ASN C 1 59  ? -14.454 -1.997  -5.696  1   36.64  ? 229 ASN B CA  1 
ATOM   5020 C C   . ASN C 1 59  ? -15.226 -2.425  -4.446  1   37     ? 229 ASN B C   1 
ATOM   5021 O O   . ASN C 1 59  ? -15.991 -1.631  -3.894  1   42.38  ? 229 ASN B O   1 
ATOM   5022 C CB  . ASN C 1 59  ? -15.183 -2.377  -6.984  1   37.07  ? 229 ASN B CB  1 
ATOM   5023 C CG  . ASN C 1 59  ? -14.819 -1.498  -8.156  1   40.7   ? 229 ASN B CG  1 
ATOM   5024 O OD1 . ASN C 1 59  ? -14.072 -0.518  -8.015  1   37.69  ? 229 ASN B OD1 1 
ATOM   5025 N ND2 . ASN C 1 59  ? -15.361 -1.834  -9.319  1   45.74  ? 229 ASN B ND2 1 
ATOM   5026 N N   . GLU C 1 60  ? -15.036 -3.687  -4.027  1   33.13  ? 230 GLU B N   1 
ATOM   5027 C CA  . GLU C 1 60  ? -15.748 -4.263  -2.898  1   31.87  ? 230 GLU B CA  1 
ATOM   5028 C C   . GLU C 1 60  ? -15.577 -3.385  -1.65   1   33.11  ? 230 GLU B C   1 
ATOM   5029 O O   . GLU C 1 60  ? -16.516 -3.219  -0.867  1   33.92  ? 230 GLU B O   1 
ATOM   5030 C CB  . GLU C 1 60  ? -15.164 -5.653  -2.654  1   31.6   ? 230 GLU B CB  1 
ATOM   5031 C CG  . GLU C 1 60  ? -15.791 -6.423  -1.5    1   30.18  ? 230 GLU B CG  1 
ATOM   5032 C CD  . GLU C 1 60  ? -17.271 -6.662  -1.704  1   32.86  ? 230 GLU B CD  1 
ATOM   5033 O OE1 . GLU C 1 60  ? -17.747 -6.485  -2.863  1   34.97  ? 230 GLU B OE1 1 
ATOM   5034 O OE2 . GLU C 1 60  ? -17.95  -6.993  -0.7    1   33.74  ? 230 GLU B OE2 1 
ATOM   5035 N N   . THR C 1 61  ? -14.363 -2.852  -1.467  1   31.88  ? 231 THR B N   1 
ATOM   5036 C CA  . THR C 1 61  ? -14.005 -2.028  -0.324  1   33.69  ? 231 THR B CA  1 
ATOM   5037 C C   . THR C 1 61  ? -14.908 -0.795  -0.289  1   35.17  ? 231 THR B C   1 
ATOM   5038 O O   . THR C 1 61  ? -15.477 -0.481  0.768   1   33.48  ? 231 THR B O   1 
ATOM   5039 C CB  . THR C 1 61  ? -12.527 -1.638  -0.394  1   34.56  ? 231 THR B CB  1 
ATOM   5040 O OG1 . THR C 1 61  ? -11.745 -2.824  -0.507  1   33.61  ? 231 THR B OG1 1 
ATOM   5041 C CG2 . THR C 1 61  ? -12.082 -0.826  0.81    1   34.15  ? 231 THR B CG2 1 
ATOM   5042 N N   . LEU C 1 62  ? -15.025 -0.116  -1.451  1   32.75  ? 232 LEU B N   1 
ATOM   5043 C CA  . LEU C 1 62  ? -15.93  1.013   -1.582  1   30.4   ? 232 LEU B CA  1 
ATOM   5044 C C   . LEU C 1 62  ? -17.324 0.629   -1.072  1   30.67  ? 232 LEU B C   1 
ATOM   5045 O O   . LEU C 1 62  ? -17.819 1.24    -0.114  1   31.23  ? 232 LEU B O   1 
ATOM   5046 C CB  . LEU C 1 62  ? -15.972 1.505   -3.025  1   29.04  ? 232 LEU B CB  1 
ATOM   5047 C CG  . LEU C 1 62  ? -16.911 2.688   -3.316  1   28.09  ? 232 LEU B CG  1 
ATOM   5048 C CD1 . LEU C 1 62  ? -16.499 3.945   -2.587  1   27.94  ? 232 LEU B CD1 1 
ATOM   5049 C CD2 . LEU C 1 62  ? -17.055 2.984   -4.807  1   26.85  ? 232 LEU B CD2 1 
ATOM   5050 N N   . HIS C 1 63  ? -17.941 -0.383  -1.714  1   29.03  ? 233 HIS B N   1 
ATOM   5051 C CA  . HIS C 1 63  ? -19.305 -0.794  -1.399  1   30.13  ? 233 HIS B CA  1 
ATOM   5052 C C   . HIS C 1 63  ? -19.517 -1.104  0.094   1   30.15  ? 233 HIS B C   1 
ATOM   5053 O O   . HIS C 1 63  ? -20.578 -0.807  0.658   1   26.81  ? 233 HIS B O   1 
ATOM   5054 C CB  . HIS C 1 63  ? -19.707 -1.986  -2.27   1   31.49  ? 233 HIS B CB  1 
ATOM   5055 C CG  . HIS C 1 63  ? -20.108 -1.647  -3.664  1   35.33  ? 233 HIS B CG  1 
ATOM   5056 N ND1 . HIS C 1 63  ? -19.204 -1.264  -4.627  1   37.14  ? 233 HIS B ND1 1 
ATOM   5057 C CD2 . HIS C 1 63  ? -21.303 -1.664  -4.28   1   34.4   ? 233 HIS B CD2 1 
ATOM   5058 C CE1 . HIS C 1 63  ? -19.846 -1.065  -5.782  1   35.84  ? 233 HIS B CE1 1 
ATOM   5059 N NE2 . HIS C 1 63  ? -21.113 -1.301  -5.591  1   33.72  ? 233 HIS B NE2 1 
ATOM   5060 N N   . LEU C 1 64  ? -18.521 -1.762  0.71    1   31.27  ? 234 LEU B N   1 
ATOM   5061 C CA  . LEU C 1 64  ? -18.516 -2.049  2.131   1   31.49  ? 234 LEU B CA  1 
ATOM   5062 C C   . LEU C 1 64  ? -18.49  -0.751  2.935   1   32.06  ? 234 LEU B C   1 
ATOM   5063 O O   . LEU C 1 64  ? -19.27  -0.603  3.876   1   32.01  ? 234 LEU B O   1 
ATOM   5064 C CB  . LEU C 1 64  ? -17.323 -2.933  2.477   1   32.93  ? 234 LEU B CB  1 
ATOM   5065 C CG  . LEU C 1 64  ? -17.431 -4.402  2.062   1   33.8   ? 234 LEU B CG  1 
ATOM   5066 C CD1 . LEU C 1 64  ? -16.21  -5.183  2.535   1   31.13  ? 234 LEU B CD1 1 
ATOM   5067 C CD2 . LEU C 1 64  ? -18.714 -5.022  2.614   1   35.03  ? 234 LEU B CD2 1 
ATOM   5068 N N   . ALA C 1 65  ? -17.616 0.189   2.553   1   30.99  ? 235 ALA B N   1 
ATOM   5069 C CA  . ALA C 1 65  ? -17.487 1.422   3.318   1   32.28  ? 235 ALA B CA  1 
ATOM   5070 C C   . ALA C 1 65  ? -18.806 2.212   3.334   1   34.25  ? 235 ALA B C   1 
ATOM   5071 O O   . ALA C 1 65  ? -19.192 2.771   4.368   1   35.82  ? 235 ALA B O   1 
ATOM   5072 C CB  . ALA C 1 65  ? -16.33  2.235   2.799   1   31.53  ? 235 ALA B CB  1 
ATOM   5073 N N   . VAL C 1 66  ? -19.508 2.229   2.187   1   32.01  ? 236 VAL B N   1 
ATOM   5074 C CA  . VAL C 1 66  ? -20.777 2.922   2.061   1   29.59  ? 236 VAL B CA  1 
ATOM   5075 C C   . VAL C 1 66  ? -21.83  2.263   2.96    1   31.56  ? 236 VAL B C   1 
ATOM   5076 O O   . VAL C 1 66  ? -22.649 2.951   3.58    1   34.73  ? 236 VAL B O   1 
ATOM   5077 C CB  . VAL C 1 66  ? -21.196 2.949   0.584   1   26.5   ? 236 VAL B CB  1 
ATOM   5078 C CG1 . VAL C 1 66  ? -22.66  3.329   0.401   1   25.9   ? 236 VAL B CG1 1 
ATOM   5079 C CG2 . VAL C 1 66  ? -20.299 3.863   -0.228  1   27.31  ? 236 VAL B CG2 1 
ATOM   5080 N N   . ASN C 1 67  ? -21.816 0.922   3.03    1   29.78  ? 237 ASN B N   1 
ATOM   5081 C CA  . ASN C 1 67  ? -22.695 0.184   3.919   1   28.68  ? 237 ASN B CA  1 
ATOM   5082 C C   . ASN C 1 67  ? -22.465 0.637   5.372   1   30.1   ? 237 ASN B C   1 
ATOM   5083 O O   . ASN C 1 67  ? -23.403 0.867   6.144   1   29.4   ? 237 ASN B O   1 
ATOM   5084 C CB  . ASN C 1 67  ? -22.492 -1.31   3.712   1   26.9   ? 237 ASN B CB  1 
ATOM   5085 C CG  . ASN C 1 67  ? -23.267 -2.102  4.739   1   29.15  ? 237 ASN B CG  1 
ATOM   5086 O OD1 . ASN C 1 67  ? -22.689 -2.536  5.746   1   32.59  ? 237 ASN B OD1 1 
ATOM   5087 N ND2 . ASN C 1 67  ? -24.572 -2.247  4.552   1   27.47  ? 237 ASN B ND2 1 
ATOM   5088 N N   . TYR C 1 68  ? -21.187 0.761   5.754   1   30.39  ? 238 TYR B N   1 
ATOM   5089 C CA  . TYR C 1 68  ? -20.813 1.113   7.118   1   31.44  ? 238 TYR B CA  1 
ATOM   5090 C C   . TYR C 1 68  ? -21.321 2.511   7.457   1   31.58  ? 238 TYR B C   1 
ATOM   5091 O O   . TYR C 1 68  ? -21.79  2.752   8.574   1   31.55  ? 238 TYR B O   1 
ATOM   5092 C CB  . TYR C 1 68  ? -19.297 1.02    7.323   1   32.93  ? 238 TYR B CB  1 
ATOM   5093 C CG  . TYR C 1 68  ? -18.727 -0.373  7.112   1   34.92  ? 238 TYR B CG  1 
ATOM   5094 C CD1 . TYR C 1 68  ? -19.568 -1.488  6.967   1   35.49  ? 238 TYR B CD1 1 
ATOM   5095 C CD2 . TYR C 1 68  ? -17.353 -0.575  7.06    1   34.76  ? 238 TYR B CD2 1 
ATOM   5096 C CE1 . TYR C 1 68  ? -19.068 -2.763  6.757   1   34.13  ? 238 TYR B CE1 1 
ATOM   5097 C CE2 . TYR C 1 68  ? -16.842 -1.849  6.868   1   36.1   ? 238 TYR B CE2 1 
ATOM   5098 C CZ  . TYR C 1 68  ? -17.695 -2.935  6.709   1   35.84  ? 238 TYR B CZ  1 
ATOM   5099 O OH  . TYR C 1 68  ? -17.191 -4.18   6.506   1   38.42  ? 238 TYR B OH  1 
ATOM   5100 N N   . ILE C 1 69  ? -21.182 3.418   6.481   1   30.1   ? 239 ILE B N   1 
ATOM   5101 C CA  . ILE C 1 69  ? -21.594 4.796   6.627   1   30.81  ? 239 ILE B CA  1 
ATOM   5102 C C   . ILE C 1 69  ? -23.105 4.853   6.831   1   32.19  ? 239 ILE B C   1 
ATOM   5103 O O   . ILE C 1 69  ? -23.581 5.505   7.761   1   33.52  ? 239 ILE B O   1 
ATOM   5104 C CB  . ILE C 1 69  ? -21.147 5.625   5.412   1   30.14  ? 239 ILE B CB  1 
ATOM   5105 C CG1 . ILE C 1 69  ? -19.639 5.781   5.356   1   29.79  ? 239 ILE B CG1 1 
ATOM   5106 C CG2 . ILE C 1 69  ? -21.834 6.984   5.447   1   30.98  ? 239 ILE B CG2 1 
ATOM   5107 C CD1 . ILE C 1 69  ? -19.111 6.082   3.973   1   28.83  ? 239 ILE B CD1 1 
ATOM   5108 N N   . ASP C 1 70  ? -23.847 4.17    5.957   1   31.78  ? 240 ASP B N   1 
ATOM   5109 C CA  . ASP C 1 70  ? -25.298 4.237   5.993   1   34.41  ? 240 ASP B CA  1 
ATOM   5110 C C   . ASP C 1 70  ? -25.816 3.666   7.316   1   36.25  ? 240 ASP B C   1 
ATOM   5111 O O   . ASP C 1 70  ? -26.718 4.249   7.923   1   38.29  ? 240 ASP B O   1 
ATOM   5112 C CB  . ASP C 1 70  ? -25.916 3.576   4.769   1   36.38  ? 240 ASP B CB  1 
ATOM   5113 C CG  . ASP C 1 70  ? -25.863 4.369   3.471   1   40.77  ? 240 ASP B CG  1 
ATOM   5114 O OD1 . ASP C 1 70  ? -25.788 5.62    3.558   1   43.65  ? 240 ASP B OD1 1 
ATOM   5115 O OD2 . ASP C 1 70  ? -25.893 3.736   2.377   1   42.17  ? 240 ASP B OD2 1 
ATOM   5116 N N   . ARG C 1 71  ? -25.238 2.532   7.763   1   33.65  ? 241 ARG B N   1 
ATOM   5117 C CA  . ARG C 1 71  ? -25.684 1.879   8.98    1   33.2   ? 241 ARG B CA  1 
ATOM   5118 C C   . ARG C 1 71  ? -25.321 2.736   10.183  1   35.31  ? 241 ARG B C   1 
ATOM   5119 O O   . ARG C 1 71  ? -26.089 2.786   11.14   1   38.1   ? 241 ARG B O   1 
ATOM   5120 C CB  . ARG C 1 71  ? -25.087 0.487   9.162   1   32.57  ? 241 ARG B CB  1 
ATOM   5121 C CG  . ARG C 1 71  ? -25.922 -0.583  8.472   1   34.09  ? 241 ARG B CG  1 
ATOM   5122 C CD  . ARG C 1 71  ? -25.154 -1.833  8.115   1   33.49  ? 241 ARG B CD  1 
ATOM   5123 N NE  . ARG C 1 71  ? -24.701 -2.528  9.324   1   35.61  ? 241 ARG B NE  1 
ATOM   5124 C CZ  . ARG C 1 71  ? -23.601 -3.291  9.373   1   36.67  ? 241 ARG B CZ  1 
ATOM   5125 N NH1 . ARG C 1 71  ? -22.89  -3.533  8.274   1   34.22  ? 241 ARG B NH1 1 
ATOM   5126 N NH2 . ARG C 1 71  ? -23.223 -3.788  10.541  1   37.11  ? 241 ARG B NH2 1 
ATOM   5127 N N   . PHE C 1 72  ? -24.145 3.38    10.133  1   33.85  ? 242 PHE B N   1 
ATOM   5128 C CA  . PHE C 1 72  ? -23.724 4.308   11.174  1   34.26  ? 242 PHE B CA  1 
ATOM   5129 C C   . PHE C 1 72  ? -24.669 5.508   11.241  1   35.04  ? 242 PHE B C   1 
ATOM   5130 O O   . PHE C 1 72  ? -25.243 5.796   12.291  1   35.9   ? 242 PHE B O   1 
ATOM   5131 C CB  . PHE C 1 72  ? -22.261 4.7     10.966  1   33.56  ? 242 PHE B CB  1 
ATOM   5132 C CG  . PHE C 1 72  ? -21.69  5.495   12.128  1   34.7   ? 242 PHE B CG  1 
ATOM   5133 C CD1 . PHE C 1 72  ? -21.19  4.846   13.248  1   34.76  ? 242 PHE B CD1 1 
ATOM   5134 C CD2 . PHE C 1 72  ? -21.671 6.888   12.099  1   36.1   ? 242 PHE B CD2 1 
ATOM   5135 C CE1 . PHE C 1 72  ? -20.672 5.582   14.305  1   37.26  ? 242 PHE B CE1 1 
ATOM   5136 C CE2 . PHE C 1 72  ? -21.15  7.617   13.152  1   37.95  ? 242 PHE B CE2 1 
ATOM   5137 C CZ  . PHE C 1 72  ? -20.652 6.963   14.263  1   38.46  ? 242 PHE B CZ  1 
ATOM   5138 N N   . LEU C 1 73  ? -24.825 6.204   10.111  1   34.7   ? 243 LEU B N   1 
ATOM   5139 C CA  . LEU C 1 73  ? -25.671 7.388   10.038  1   36.59  ? 243 LEU B CA  1 
ATOM   5140 C C   . LEU C 1 73  ? -27.135 7.062   10.364  1   39.46  ? 243 LEU B C   1 
ATOM   5141 O O   . LEU C 1 73  ? -27.923 7.999   10.557  1   43.17  ? 243 LEU B O   1 
ATOM   5142 C CB  . LEU C 1 73  ? -25.545 8.057   8.669   1   34.2   ? 243 LEU B CB  1 
ATOM   5143 C CG  . LEU C 1 73  ? -24.2   8.698   8.318   1   33.08  ? 243 LEU B CG  1 
ATOM   5144 C CD1 . LEU C 1 73  ? -24.219 9.342   6.963   1   31.73  ? 243 LEU B CD1 1 
ATOM   5145 C CD2 . LEU C 1 73  ? -23.77  9.712   9.342   1   35.2   ? 243 LEU B CD2 1 
ATOM   5146 N N   . SER C 1 74  ? -27.499 5.763   10.458  1   38.88  ? 244 SER B N   1 
ATOM   5147 C CA  . SER C 1 74  ? -28.862 5.34    10.782  1   39.62  ? 244 SER B CA  1 
ATOM   5148 C C   . SER C 1 74  ? -29.203 5.38    12.279  1   41.25  ? 244 SER B C   1 
ATOM   5149 O O   . SER C 1 74  ? -30.388 5.425   12.613  1   43.78  ? 244 SER B O   1 
ATOM   5150 C CB  . SER C 1 74  ? -29.196 4.003   10.215  1   38.63  ? 244 SER B CB  1 
ATOM   5151 O OG  . SER C 1 74  ? -29.268 4.071   8.804   1   40.61  ? 244 SER B OG  1 
ATOM   5152 N N   . SER C 1 75  ? -28.205 5.33    13.181  1   40.55  ? 245 SER B N   1 
ATOM   5153 C CA  . SER C 1 75  ? -28.488 5.503   14.601  1   42.31  ? 245 SER B CA  1 
ATOM   5154 C C   . SER C 1 75  ? -27.777 6.716   15.204  1   44.32  ? 245 SER B C   1 
ATOM   5155 O O   . SER C 1 75  ? -28.207 7.194   16.26   1   47.68  ? 245 SER B O   1 
ATOM   5156 C CB  . SER C 1 75  ? -28.209 4.27    15.399  1   41.86  ? 245 SER B CB  1 
ATOM   5157 O OG  . SER C 1 75  ? -26.842 3.936   15.256  1   41.84  ? 245 SER B OG  1 
ATOM   5158 N N   . MET C 1 76  ? -26.7   7.198   14.555  1   42.24  ? 246 MET B N   1 
ATOM   5159 C CA  . MET C 1 76  ? -25.871 8.262   15.108  1   42.7   ? 246 MET B CA  1 
ATOM   5160 C C   . MET C 1 76  ? -26.044 9.583   14.353  1   43.86  ? 246 MET B C   1 
ATOM   5161 O O   . MET C 1 76  ? -25.788 9.659   13.151  1   42.22  ? 246 MET B O   1 
ATOM   5162 C CB  . MET C 1 76  ? -24.402 7.86    15.045  1   40.71  ? 246 MET B CB  1 
ATOM   5163 C CG  . MET C 1 76  ? -24.095 6.562   15.759  1   39.35  ? 246 MET B CG  1 
ATOM   5164 S SD  . MET C 1 76  ? -24.058 6.814   17.535  1   40.82  ? 246 MET B SD  1 
ATOM   5165 C CE  . MET C 1 76  ? -22.781 8.028   17.888  1   43.28  ? 246 MET B CE  1 
ATOM   5166 N N   . SER C 1 77  ? -26.452 10.634  15.087  1   46.29  ? 247 SER B N   1 
ATOM   5167 C CA  . SER C 1 77  ? -26.434 12.009  14.596  1   46.61  ? 247 SER B CA  1 
ATOM   5168 C C   . SER C 1 77  ? -24.996 12.481  14.404  1   46.41  ? 247 SER B C   1 
ATOM   5169 O O   . SER C 1 77  ? -24.168 12.32   15.305  1   49.5   ? 247 SER B O   1 
ATOM   5170 C CB  . SER C 1 77  ? -27.152 12.945  15.534  1   48.08  ? 247 SER B CB  1 
ATOM   5171 O OG  . SER C 1 77  ? -28.54  12.915  15.265  1   48.93  ? 247 SER B OG  1 
ATOM   5172 N N   . VAL C 1 78  ? -24.738 13.097  13.245  1   43.57  ? 248 VAL B N   1 
ATOM   5173 C CA  . VAL C 1 78  ? -23.426 13.604  12.881  1   42.35  ? 248 VAL B CA  1 
ATOM   5174 C C   . VAL C 1 78  ? -23.588 14.989  12.25   1   43.31  ? 248 VAL B C   1 
ATOM   5175 O O   . VAL C 1 78  ? -24.48  15.199  11.423  1   44.03  ? 248 VAL B O   1 
ATOM   5176 C CB  . VAL C 1 78  ? -22.81  12.588  11.908  1   39.97  ? 248 VAL B CB  1 
ATOM   5177 C CG1 . VAL C 1 78  ? -21.438 13.023  11.427  1   40.7   ? 248 VAL B CG1 1 
ATOM   5178 C CG2 . VAL C 1 78  ? -22.697 11.203  12.535  1   39.42  ? 248 VAL B CG2 1 
ATOM   5179 N N   . LEU C 1 79  ? -22.768 15.95   12.702  1   44.03  ? 249 LEU B N   1 
ATOM   5180 C CA  . LEU C 1 79  ? -22.78  17.294  12.146  1   44.71  ? 249 LEU B CA  1 
ATOM   5181 C C   . LEU C 1 79  ? -22.023 17.271  10.826  1   43.81  ? 249 LEU B C   1 
ATOM   5182 O O   . LEU C 1 79  ? -21.234 16.37   10.591  1   42.2   ? 249 LEU B O   1 
ATOM   5183 C CB  . LEU C 1 79  ? -22.103 18.269  13.1    1   46.64  ? 249 LEU B CB  1 
ATOM   5184 C CG  . LEU C 1 79  ? -22.807 18.555  14.427  1   48.67  ? 249 LEU B CG  1 
ATOM   5185 C CD1 . LEU C 1 79  ? -21.99  19.576  15.202  1   51.05  ? 249 LEU B CD1 1 
ATOM   5186 C CD2 . LEU C 1 79  ? -24.216 19.056  14.226  1   49.18  ? 249 LEU B CD2 1 
ATOM   5187 N N   . ARG C 1 80  ? -22.222 18.292  9.991   1   45.1   ? 250 ARG B N   1 
ATOM   5188 C CA  . ARG C 1 80  ? -21.626 18.292  8.672   1   44.15  ? 250 ARG B CA  1 
ATOM   5189 C C   . ARG C 1 80  ? -20.101 18.244  8.79    1   43.95  ? 250 ARG B C   1 
ATOM   5190 O O   . ARG C 1 80  ? -19.435 17.65   7.926   1   43.3   ? 250 ARG B O   1 
ATOM   5191 C CB  . ARG C 1 80  ? -22.142 19.488  7.864   1   46.49  ? 250 ARG B CB  1 
ATOM   5192 C CG  . ARG C 1 80  ? -21.418 20.777  8.216   1   50.73  ? 250 ARG B CG  1 
ATOM   5193 C CD  . ARG C 1 80  ? -22.229 21.969  7.778   1   54.91  ? 250 ARG B CD  1 
ATOM   5194 N NE  . ARG C 1 80  ? -23.627 21.776  8.174   1   56.42  ? 250 ARG B NE  1 
ATOM   5195 C CZ  . ARG C 1 80  ? -24.668 22.231  7.496   1   57.55  ? 250 ARG B CZ  1 
ATOM   5196 N NH1 . ARG C 1 80  ? -24.496 23.123  6.531   1   57.7   ? 250 ARG B NH1 1 
ATOM   5197 N NH2 . ARG C 1 80  ? -25.882 21.815  7.823   1   58.37  ? 250 ARG B NH2 1 
ATOM   5198 N N   . GLY C 1 81  ? -19.563 18.854  9.862   1   44.52  ? 251 GLY B N   1 
ATOM   5199 C CA  . GLY C 1 81  ? -18.123 18.983  10.039  1   44.66  ? 251 GLY B CA  1 
ATOM   5200 C C   . GLY C 1 81  ? -17.39  17.646  10.217  1   42.92  ? 251 GLY B C   1 
ATOM   5201 O O   . GLY C 1 81  ? -16.175 17.571  10.003  1   42.72  ? 251 GLY B O   1 
ATOM   5202 N N   . LYS C 1 82  ? -18.138 16.602  10.63   1   41.37  ? 252 LYS B N   1 
ATOM   5203 C CA  . LYS C 1 82  ? -17.584 15.321  11.032  1   39.33  ? 252 LYS B CA  1 
ATOM   5204 C C   . LYS C 1 82  ? -18.059 14.195  10.122  1   37.31  ? 252 LYS B C   1 
ATOM   5205 O O   . LYS C 1 82  ? -17.718 13.024  10.342  1   36.06  ? 252 LYS B O   1 
ATOM   5206 C CB  . LYS C 1 82  ? -18.031 15.038  12.462  1   39.58  ? 252 LYS B CB  1 
ATOM   5207 C CG  . LYS C 1 82  ? -17.416 15.956  13.508  1   41.58  ? 252 LYS B CG  1 
ATOM   5208 C CD  . LYS C 1 82  ? -15.918 15.746  13.658  1   41.61  ? 252 LYS B CD  1 
ATOM   5209 C CE  . LYS C 1 82  ? -15.417 16.224  14.953  1   43.71  ? 252 LYS B CE  1 
ATOM   5210 N NZ  . LYS C 1 82  ? -16.128 17.439  15.311  1   45.64  ? 252 LYS B NZ  1 
ATOM   5211 N N   . LEU C 1 83  ? -18.825 14.551  9.082   1   37.22  ? 253 LEU B N   1 
ATOM   5212 C CA  . LEU C 1 83  ? -19.34  13.54   8.174   1   35.81  ? 253 LEU B CA  1 
ATOM   5213 C C   . LEU C 1 83  ? -18.176 12.805  7.496   1   35.59  ? 253 LEU B C   1 
ATOM   5214 O O   . LEU C 1 83  ? -18.281 11.611  7.183   1   33.85  ? 253 LEU B O   1 
ATOM   5215 C CB  . LEU C 1 83  ? -20.288 14.158  7.154   1   34.9   ? 253 LEU B CB  1 
ATOM   5216 C CG  . LEU C 1 83  ? -20.793 13.172  6.093   1   32.94  ? 253 LEU B CG  1 
ATOM   5217 C CD1 . LEU C 1 83  ? -21.448 11.945  6.697   1   31.62  ? 253 LEU B CD1 1 
ATOM   5218 C CD2 . LEU C 1 83  ? -21.766 13.854  5.164   1   33.21  ? 253 LEU B CD2 1 
ATOM   5219 N N   . GLN C 1 84  ? -17.071 13.538  7.287   1   36.34  ? 254 GLN B N   1 
ATOM   5220 C CA  . GLN C 1 84  ? -15.919 13.011  6.585   1   35.45  ? 254 GLN B CA  1 
ATOM   5221 C C   . GLN C 1 84  ? -15.106 12.086  7.488   1   36.55  ? 254 GLN B C   1 
ATOM   5222 O O   . GLN C 1 84  ? -14.515 11.125  7.005   1   36.33  ? 254 GLN B O   1 
ATOM   5223 C CB  . GLN C 1 84  ? -15.042 14.135  6.054   1   36.35  ? 254 GLN B CB  1 
ATOM   5224 C CG  . GLN C 1 84  ? -14.079 13.662  4.975   1   35.97  ? 254 GLN B CG  1 
ATOM   5225 C CD  . GLN C 1 84  ? -13.05  14.689  4.538   1   38.45  ? 254 GLN B CD  1 
ATOM   5226 O OE1 . GLN C 1 84  ? -12.256 14.424  3.616   1   37.87  ? 254 GLN B OE1 1 
ATOM   5227 N NE2 . GLN C 1 84  ? -13.028 15.847  5.207   1   40.19  ? 254 GLN B NE2 1 
ATOM   5228 N N   . LEU C 1 85  ? -15.062 12.372  8.796   1   38.07  ? 255 LEU B N   1 
ATOM   5229 C CA  . LEU C 1 85  ? -14.3   11.526  9.696   1   38.14  ? 255 LEU B CA  1 
ATOM   5230 C C   . LEU C 1 85  ? -14.974 10.162  9.774   1   37.68  ? 255 LEU B C   1 
ATOM   5231 O O   . LEU C 1 85  ? -14.292 9.138   9.78    1   37.82  ? 255 LEU B O   1 
ATOM   5232 C CB  . LEU C 1 85  ? -14.167 12.172  11.066  1   39.68  ? 255 LEU B CB  1 
ATOM   5233 C CG  . LEU C 1 85  ? -13.402 11.369  12.118  1   40.16  ? 255 LEU B CG  1 
ATOM   5234 C CD1 . LEU C 1 85  ? -12.001 10.992  11.696  1   39.58  ? 255 LEU B CD1 1 
ATOM   5235 C CD2 . LEU C 1 85  ? -13.362 12.162  13.414  1   42.83  ? 255 LEU B CD2 1 
ATOM   5236 N N   . VAL C 1 86  ? -16.316 10.164  9.799   1   36.95  ? 256 VAL B N   1 
ATOM   5237 C CA  . VAL C 1 86  ? -17.111 8.943   9.731   1   33.85  ? 256 VAL B CA  1 
ATOM   5238 C C   . VAL C 1 86  ? -16.791 8.216   8.426   1   32.05  ? 256 VAL B C   1 
ATOM   5239 O O   . VAL C 1 86  ? -16.704 6.994   8.408   1   31.04  ? 256 VAL B O   1 
ATOM   5240 C CB  . VAL C 1 86  ? -18.618 9.224   9.876   1   32.53  ? 256 VAL B CB  1 
ATOM   5241 C CG1 . VAL C 1 86  ? -19.456 7.966   9.847   1   30.74  ? 256 VAL B CG1 1 
ATOM   5242 C CG2 . VAL C 1 86  ? -18.918 9.966   11.155  1   34.42  ? 256 VAL B CG2 1 
ATOM   5243 N N   . GLY C 1 87  ? -16.598 8.97    7.34    1   32.07  ? 257 GLY B N   1 
ATOM   5244 C CA  . GLY C 1 87  ? -16.344 8.363   6.043   1   31.27  ? 257 GLY B CA  1 
ATOM   5245 C C   . GLY C 1 87  ? -14.949 7.753   5.959   1   31.82  ? 257 GLY B C   1 
ATOM   5246 O O   . GLY C 1 87  ? -14.77  6.68    5.376   1   31.04  ? 257 GLY B O   1 
ATOM   5247 N N   . THR C 1 88  ? -13.977 8.441   6.575   1   33.31  ? 258 THR B N   1 
ATOM   5248 C CA  . THR C 1 88  ? -12.583 8.03    6.561   1   33.59  ? 258 THR B CA  1 
ATOM   5249 C C   . THR C 1 88  ? -12.411 6.79    7.438   1   33.93  ? 258 THR B C   1 
ATOM   5250 O O   . THR C 1 88  ? -11.625 5.916   7.116   1   34.55  ? 258 THR B O   1 
ATOM   5251 C CB  . THR C 1 88  ? -11.702 9.192   7.019   1   35.91  ? 258 THR B CB  1 
ATOM   5252 O OG1 . THR C 1 88  ? -11.909 10.283  6.121   1   36.83  ? 258 THR B OG1 1 
ATOM   5253 C CG2 . THR C 1 88  ? -10.224 8.846   7.028   1   36.82  ? 258 THR B CG2 1 
ATOM   5254 N N   . ALA C 1 89  ? -13.137 6.714   8.558   1   34.82  ? 259 ALA B N   1 
ATOM   5255 C CA  . ALA C 1 89  ? -13.084 5.539   9.421   1   34.17  ? 259 ALA B CA  1 
ATOM   5256 C C   . ALA C 1 89  ? -13.75  4.347   8.74    1   31.81  ? 259 ALA B C   1 
ATOM   5257 O O   . ALA C 1 89  ? -13.233 3.236   8.818   1   31.68  ? 259 ALA B O   1 
ATOM   5258 C CB  . ALA C 1 89  ? -13.741 5.818   10.749  1   34.98  ? 259 ALA B CB  1 
ATOM   5259 N N   . ALA C 1 90  ? -14.897 4.592   8.103   1   29.68  ? 260 ALA B N   1 
ATOM   5260 C CA  . ALA C 1 90  ? -15.566 3.572   7.33    1   28.98  ? 260 ALA B CA  1 
ATOM   5261 C C   . ALA C 1 90  ? -14.578 2.954   6.34    1   30.86  ? 260 ALA B C   1 
ATOM   5262 O O   . ALA C 1 90  ? -14.493 1.727   6.232   1   31.79  ? 260 ALA B O   1 
ATOM   5263 C CB  . ALA C 1 90  ? -16.762 4.17    6.634   1   27.31  ? 260 ALA B CB  1 
ATOM   5264 N N   . MET C 1 91  ? -13.843 3.808   5.603   1   32.13  ? 261 MET B N   1 
ATOM   5265 C CA  . MET C 1 91  ? -13.029 3.318   4.507   1   30.67  ? 261 MET B CA  1 
ATOM   5266 C C   . MET C 1 91  ? -11.831 2.575   5.09    1   30.79  ? 261 MET B C   1 
ATOM   5267 O O   . MET C 1 91  ? -11.394 1.579   4.52    1   30.01  ? 261 MET B O   1 
ATOM   5268 C CB  . MET C 1 91  ? -12.582 4.435   3.567   1   31.58  ? 261 MET B CB  1 
ATOM   5269 C CG  . MET C 1 91  ? -12.095 3.912   2.216   1   33.38  ? 261 MET B CG  1 
ATOM   5270 S SD  . MET C 1 91  ? -13.392 3.528   1.018   1   36     ? 261 MET B SD  1 
ATOM   5271 C CE  . MET C 1 91  ? -12.472 2.904   -0.395  1   34.71  ? 261 MET B CE  1 
ATOM   5272 N N   . LEU C 1 92  ? -11.347 3.037   6.253   1   30.55  ? 262 LEU B N   1 
ATOM   5273 C CA  . LEU C 1 92  ? -10.229 2.393   6.912   1   30.99  ? 262 LEU B CA  1 
ATOM   5274 C C   . LEU C 1 92  ? -10.633 0.974   7.328   1   31.13  ? 262 LEU B C   1 
ATOM   5275 O O   . LEU C 1 92  ? -9.855  0.03    7.173   1   31.08  ? 262 LEU B O   1 
ATOM   5276 C CB  . LEU C 1 92  ? -9.729  3.248   8.074   1   32.64  ? 262 LEU B CB  1 
ATOM   5277 C CG  . LEU C 1 92  ? -8.749  2.58    9.062   1   34.72  ? 262 LEU B CG  1 
ATOM   5278 C CD1 . LEU C 1 92  ? -7.41   2.187   8.449   1   35.1   ? 262 LEU B CD1 1 
ATOM   5279 C CD2 . LEU C 1 92  ? -8.479  3.419   10.309  1   35.88  ? 262 LEU B CD2 1 
ATOM   5280 N N   . LEU C 1 93  ? -11.862 0.81    7.839   1   30.86  ? 263 LEU B N   1 
ATOM   5281 C CA  . LEU C 1 93  ? -12.325 -0.493  8.293   1   30.89  ? 263 LEU B CA  1 
ATOM   5282 C C   . LEU C 1 93  ? -12.605 -1.411  7.106   1   30.13  ? 263 LEU B C   1 
ATOM   5283 O O   . LEU C 1 93  ? -12.23  -2.586  7.109   1   31.15  ? 263 LEU B O   1 
ATOM   5284 C CB  . LEU C 1 93  ? -13.571 -0.325  9.151   1   31.54  ? 263 LEU B CB  1 
ATOM   5285 C CG  . LEU C 1 93  ? -13.331 -0.008  10.625  1   33.66  ? 263 LEU B CG  1 
ATOM   5286 C CD1 . LEU C 1 93  ? -14.633 0.381   11.3    1   32.76  ? 263 LEU B CD1 1 
ATOM   5287 C CD2 . LEU C 1 93  ? -12.724 -1.235  11.3    1   34.81  ? 263 LEU B CD2 1 
ATOM   5288 N N   . ALA C 1 94  ? -13.289 -0.869  6.094   1   28.32  ? 264 ALA B N   1 
ATOM   5289 C CA  . ALA C 1 94  ? -13.484 -1.586  4.853   1   26.99  ? 264 ALA B CA  1 
ATOM   5290 C C   . ALA C 1 94  ? -12.158 -2.141  4.352   1   29.09  ? 264 ALA B C   1 
ATOM   5291 O O   . ALA C 1 94  ? -12.076 -3.322  4.028   1   29.92  ? 264 ALA B O   1 
ATOM   5292 C CB  . ALA C 1 94  ? -14.071 -0.668  3.841   1   26.36  ? 264 ALA B CB  1 
ATOM   5293 N N   . SER C 1 95  ? -11.127 -1.282  4.301   1   30.51  ? 265 SER B N   1 
ATOM   5294 C CA  . SER C 1 95  ? -9.842  -1.644  3.722   1   30.57  ? 265 SER B CA  1 
ATOM   5295 C C   . SER C 1 95  ? -9.239  -2.797  4.506   1   30.68  ? 265 SER B C   1 
ATOM   5296 O O   . SER C 1 95  ? -8.866  -3.81   3.919   1   31.56  ? 265 SER B O   1 
ATOM   5297 C CB  . SER C 1 95  ? -8.893  -0.496  3.691   1   33.46  ? 265 SER B CB  1 
ATOM   5298 O OG  . SER C 1 95  ? -9.513  0.625   3.092   1   36.43  ? 265 SER B OG  1 
ATOM   5299 N N   . LYS C 1 96  ? -9.177  -2.646  5.835   1   30.57  ? 266 LYS B N   1 
ATOM   5300 C CA  . LYS C 1 96  ? -8.582  -3.668  6.679   1   29.71  ? 266 LYS B CA  1 
ATOM   5301 C C   . LYS C 1 96  ? -9.281  -5.005  6.453   1   27.96  ? 266 LYS B C   1 
ATOM   5302 O O   . LYS C 1 96  ? -8.635  -6.031  6.448   1   28.13  ? 266 LYS B O   1 
ATOM   5303 C CB  . LYS C 1 96  ? -8.677  -3.22   8.131   1   30.61  ? 266 LYS B CB  1 
ATOM   5304 C CG  . LYS C 1 96  ? -7.731  -2.09   8.477   1   32.06  ? 266 LYS B CG  1 
ATOM   5305 C CD  . LYS C 1 96  ? -8.033  -1.471  9.843   1   32.44  ? 266 LYS B CD  1 
ATOM   5306 C CE  . LYS C 1 96  ? -6.807  -1.044  10.556  1   34.14  ? 266 LYS B CE  1 
ATOM   5307 N NZ  . LYS C 1 96  ? -7.159  -0.668  11.922  1   36.04  ? 266 LYS B NZ  1 
ATOM   5308 N N   . PHE C 1 97  ? -10.589 -4.98   6.213   1   26.7   ? 267 PHE B N   1 
ATOM   5309 C CA  . PHE C 1 97  ? -11.338 -6.208  6.032   1   27.18  ? 267 PHE B CA  1 
ATOM   5310 C C   . PHE C 1 97  ? -11.032 -6.866  4.683   1   27.81  ? 267 PHE B C   1 
ATOM   5311 O O   . PHE C 1 97  ? -10.783 -8.077  4.601   1   26.8   ? 267 PHE B O   1 
ATOM   5312 C CB  . PHE C 1 97  ? -12.825 -5.861  6.107   1   26.32  ? 267 PHE B CB  1 
ATOM   5313 C CG  . PHE C 1 97  ? -13.743 -7.068  6.147   1   26.53  ? 267 PHE B CG  1 
ATOM   5314 C CD1 . PHE C 1 97  ? -14.022 -7.71   7.347   1   28.32  ? 267 PHE B CD1 1 
ATOM   5315 C CD2 . PHE C 1 97  ? -14.334 -7.554  4.99    1   26.52  ? 267 PHE B CD2 1 
ATOM   5316 C CE1 . PHE C 1 97  ? -14.862 -8.822  7.387   1   29.24  ? 267 PHE B CE1 1 
ATOM   5317 C CE2 . PHE C 1 97  ? -15.174 -8.666  5.026   1   27.13  ? 267 PHE B CE2 1 
ATOM   5318 C CZ  . PHE C 1 97  ? -15.45  -9.295  6.223   1   27.78  ? 267 PHE B CZ  1 
ATOM   5319 N N   . GLU C 1 98  ? -11.066 -6.057  3.617   1   28.11  ? 268 GLU B N   1 
ATOM   5320 C CA  . GLU C 1 98  ? -11.227 -6.576  2.266   1   28.69  ? 268 GLU B CA  1 
ATOM   5321 C C   . GLU C 1 98  ? -9.896  -6.605  1.514   1   30.2   ? 268 GLU B C   1 
ATOM   5322 O O   . GLU C 1 98  ? -9.741  -7.401  0.593   1   30.04  ? 268 GLU B O   1 
ATOM   5323 C CB  . GLU C 1 98  ? -12.273 -5.74   1.53    1   29.04  ? 268 GLU B CB  1 
ATOM   5324 C CG  . GLU C 1 98  ? -12.812 -6.392  0.263   1   32.3   ? 268 GLU B CG  1 
ATOM   5325 C CD  . GLU C 1 98  ? -13.316 -7.817  0.424   1   36.37  ? 268 GLU B CD  1 
ATOM   5326 O OE1 . GLU C 1 98  ? -14.161 -8.047  1.341   1   36.23  ? 268 GLU B OE1 1 
ATOM   5327 O OE2 . GLU C 1 98  ? -12.884 -8.685  -0.388  1   37.35  ? 268 GLU B OE2 1 
ATOM   5328 N N   . GLU C 1 99  ? -8.944  -5.751  1.916   1   31.59  ? 269 GLU B N   1 
ATOM   5329 C CA  . GLU C 1 99  ? -7.741  -5.496  1.142   1   33.34  ? 269 GLU B CA  1 
ATOM   5330 C C   . GLU C 1 99  ? -6.575  -6.343  1.633   1   35.7   ? 269 GLU B C   1 
ATOM   5331 O O   . GLU C 1 99  ? -6.295  -6.403  2.834   1   36.62  ? 269 GLU B O   1 
ATOM   5332 C CB  . GLU C 1 99  ? -7.257  -4.052  1.309   1   36.12  ? 269 GLU B CB  1 
ATOM   5333 C CG  . GLU C 1 99  ? -8.139  -3.027  0.604   1   36.45  ? 269 GLU B CG  1 
ATOM   5334 C CD  . GLU C 1 99  ? -8.183  -3.136  -0.913  1   39.01  ? 269 GLU B CD  1 
ATOM   5335 O OE1 . GLU C 1 99  ? -7.2    -3.634  -1.519  1   42.76  ? 269 GLU B OE1 1 
ATOM   5336 O OE2 . GLU C 1 99  ? -9.234  -2.75   -1.477  1   37.11  ? 269 GLU B OE2 1 
ATOM   5337 N N   . ILE C 1 100 ? -5.838  -6.909  0.661   1   36.07  ? 270 ILE B N   1 
ATOM   5338 C CA  . ILE C 1 100 ? -4.595  -7.594  0.963   1   36.52  ? 270 ILE B CA  1 
ATOM   5339 C C   . ILE C 1 100 ? -3.639  -6.607  1.614   1   37.45  ? 270 ILE B C   1 
ATOM   5340 O O   . ILE C 1 100 ? -3.007  -6.949  2.611   1   38.31  ? 270 ILE B O   1 
ATOM   5341 C CB  . ILE C 1 100 ? -3.971  -8.242  -0.281  1   34.95  ? 270 ILE B CB  1 
ATOM   5342 C CG1 . ILE C 1 100 ? -4.929  -9.24   -0.929  1   35.03  ? 270 ILE B CG1 1 
ATOM   5343 C CG2 . ILE C 1 100 ? -2.659  -8.901  0.124   1   35.01  ? 270 ILE B CG2 1 
ATOM   5344 C CD1 . ILE C 1 100 ? -4.507  -9.722  -2.304  1   36.28  ? 270 ILE B CD1 1 
ATOM   5345 N N   . TYR C 1 101 ? -3.517  -5.424  0.989   1   39.34  ? 271 TYR B N   1 
ATOM   5346 C CA  . TYR C 1 101 ? -2.615  -4.366  1.423   1   42.59  ? 271 TYR B CA  1 
ATOM   5347 C C   . TYR C 1 101 ? -3.407  -3.099  1.732   1   42.15  ? 271 TYR B C   1 
ATOM   5348 O O   . TYR C 1 101 ? -3.414  -2.155  0.946   1   44.39  ? 271 TYR B O   1 
ATOM   5349 C CB  . TYR C 1 101 ? -1.609  -4.062  0.309   1   44.22  ? 271 TYR B CB  1 
ATOM   5350 C CG  . TYR C 1 101 ? -0.617  -5.193  0.117   1   46.55  ? 271 TYR B CG  1 
ATOM   5351 C CD1 . TYR C 1 101 ? 0.337   -5.454  1.103   1   48.04  ? 271 TYR B CD1 1 
ATOM   5352 C CD2 . TYR C 1 101 ? -0.653  -5.999  -1.025  1   44.88  ? 271 TYR B CD2 1 
ATOM   5353 C CE1 . TYR C 1 101 ? 1.227   -6.503  0.962   1   50.6   ? 271 TYR B CE1 1 
ATOM   5354 C CE2 . TYR C 1 101 ? 0.237   -7.05   -1.176  1   46.15  ? 271 TYR B CE2 1 
ATOM   5355 C CZ  . TYR C 1 101 ? 1.167   -7.3    -0.173  1   51.94  ? 271 TYR B CZ  1 
ATOM   5356 O OH  . TYR C 1 101 ? 2.092   -8.302  -0.28   1   58.5   ? 271 TYR B OH  1 
ATOM   5357 N N   . PRO C 1 102 ? -4.096  -3.01   2.886   1   40.3   ? 272 PRO B N   1 
ATOM   5358 C CA  . PRO C 1 102 ? -4.781  -1.771  3.245   1   38.72  ? 272 PRO B CA  1 
ATOM   5359 C C   . PRO C 1 102 ? -3.766  -0.64   3.383   1   38.13  ? 272 PRO B C   1 
ATOM   5360 O O   . PRO C 1 102 ? -2.639  -0.861  3.805   1   39.23  ? 272 PRO B O   1 
ATOM   5361 C CB  . PRO C 1 102 ? -5.479  -2.121  4.571   1   38.12  ? 272 PRO B CB  1 
ATOM   5362 C CG  . PRO C 1 102 ? -4.624  -3.236  5.133   1   39.65  ? 272 PRO B CG  1 
ATOM   5363 C CD  . PRO C 1 102 ? -4.238  -4.052  3.909   1   39.48  ? 272 PRO B CD  1 
ATOM   5364 N N   . PRO C 1 103 ? -4.14   0.6     3.003   1   37.84  ? 273 PRO B N   1 
ATOM   5365 C CA  . PRO C 1 103 ? -3.381  1.799   3.377   1   39.29  ? 273 PRO B CA  1 
ATOM   5366 C C   . PRO C 1 103 ? -3.102  1.909   4.873   1   40.96  ? 273 PRO B C   1 
ATOM   5367 O O   . PRO C 1 103 ? -3.833  1.369   5.701   1   41.21  ? 273 PRO B O   1 
ATOM   5368 C CB  . PRO C 1 103 ? -4.278  2.965   2.94    1   37.92  ? 273 PRO B CB  1 
ATOM   5369 C CG  . PRO C 1 103 ? -5.218  2.377   1.924   1   36.43  ? 273 PRO B CG  1 
ATOM   5370 C CD  . PRO C 1 103 ? -5.334  0.902   2.2     1   35.84  ? 273 PRO B CD  1 
ATOM   5371 N N   . GLU C 1 104 ? -2.061  2.67    5.209   1   43.41  ? 274 GLU B N   1 
ATOM   5372 C CA  . GLU C 1 104 ? -1.801  3.056   6.581   1   47.6   ? 274 GLU B CA  1 
ATOM   5373 C C   . GLU C 1 104 ? -2.838  4.068   7.063   1   46.56  ? 274 GLU B C   1 
ATOM   5374 O O   . GLU C 1 104 ? -3.482  4.764   6.282   1   45.01  ? 274 GLU B O   1 
ATOM   5375 C CB  . GLU C 1 104 ? -0.409  3.674   6.703   1   56.03  ? 274 GLU B CB  1 
ATOM   5376 C CG  . GLU C 1 104 ? 0.733   2.723   6.346   1   64.54  ? 274 GLU B CG  1 
ATOM   5377 C CD  . GLU C 1 104 ? 2.13    3.272   6.6     1   75.19  ? 274 GLU B CD  1 
ATOM   5378 O OE1 . GLU C 1 104 ? 3.107   2.526   6.349   1   80.72  ? 274 GLU B OE1 1 
ATOM   5379 O OE2 . GLU C 1 104 ? 2.253   4.44    7.046   1   79.98  ? 274 GLU B OE2 1 
ATOM   5380 N N   . VAL C 1 105 ? -2.995  4.149   8.383   1   47.36  ? 275 VAL B N   1 
ATOM   5381 C CA  . VAL C 1 105 ? -3.784  5.215   8.97    1   47.82  ? 275 VAL B CA  1 
ATOM   5382 C C   . VAL C 1 105 ? -3.228  6.545   8.478   1   50.11  ? 275 VAL B C   1 
ATOM   5383 O O   . VAL C 1 105 ? -4.005  7.401   8.063   1   51.82  ? 275 VAL B O   1 
ATOM   5384 C CB  . VAL C 1 105 ? -3.777  5.144   10.507  1   48.61  ? 275 VAL B CB  1 
ATOM   5385 C CG1 . VAL C 1 105 ? -4.676  6.204   11.123  1   47.34  ? 275 VAL B CG1 1 
ATOM   5386 C CG2 . VAL C 1 105 ? -4.187  3.754   10.985  1   47.97  ? 275 VAL B CG2 1 
ATOM   5387 N N   . ALA C 1 106 ? -1.889  6.686   8.491   1   50.74  ? 276 ALA B N   1 
ATOM   5388 C CA  . ALA C 1 106 ? -1.221  7.917   8.087   1   50.17  ? 276 ALA B CA  1 
ATOM   5389 C C   . ALA C 1 106 ? -1.75   8.393   6.736   1   48.83  ? 276 ALA B C   1 
ATOM   5390 O O   . ALA C 1 106 ? -2.037  9.574   6.562   1   49.71  ? 276 ALA B O   1 
ATOM   5391 C CB  . ALA C 1 106 ? 0.278   7.75    8.09    1   50.02  ? 276 ALA B CB  1 
ATOM   5392 N N   . GLU C 1 107 ? -1.914  7.448   5.81    1   48.28  ? 277 GLU B N   1 
ATOM   5393 C CA  . GLU C 1 107 ? -2.394  7.729   4.47    1   49.36  ? 277 GLU B CA  1 
ATOM   5394 C C   . GLU C 1 107 ? -3.821  8.259   4.548   1   46.15  ? 277 GLU B C   1 
ATOM   5395 O O   . GLU C 1 107 ? -4.123  9.279   3.929   1   46.44  ? 277 GLU B O   1 
ATOM   5396 C CB  . GLU C 1 107 ? -2.168  6.541   3.528   1   53.88  ? 277 GLU B CB  1 
ATOM   5397 C CG  . GLU C 1 107 ? -0.735  6.444   2.995   1   64.13  ? 277 GLU B CG  1 
ATOM   5398 C CD  . GLU C 1 107 ? -0.275  5.132   2.361   1   72.87  ? 277 GLU B CD  1 
ATOM   5399 O OE1 . GLU C 1 107 ? -0.157  5.071   1.112   1   76.6   ? 277 GLU B OE1 1 
ATOM   5400 O OE2 . GLU C 1 107 ? 0.011   4.167   3.112   1   75.81  ? 277 GLU B OE2 1 
ATOM   5401 N N   . PHE C 1 108 ? -4.68   7.575   5.314   1   43.48  ? 278 PHE B N   1 
ATOM   5402 C CA  . PHE C 1 108 ? -6.026  8.064   5.574   1   42.53  ? 278 PHE B CA  1 
ATOM   5403 C C   . PHE C 1 108 ? -5.997  9.481   6.153   1   44.74  ? 278 PHE B C   1 
ATOM   5404 O O   . PHE C 1 108 ? -6.757  10.334  5.709   1   46.2   ? 278 PHE B O   1 
ATOM   5405 C CB  . PHE C 1 108 ? -6.855  7.082   6.402   1   40.79  ? 278 PHE B CB  1 
ATOM   5406 C CG  . PHE C 1 108 ? -7.314  5.888   5.589   1   40.24  ? 278 PHE B CG  1 
ATOM   5407 C CD1 . PHE C 1 108 ? -8.306  6.026   4.623   1   39.53  ? 278 PHE B CD1 1 
ATOM   5408 C CD2 . PHE C 1 108 ? -6.724  4.639   5.753   1   41.31  ? 278 PHE B CD2 1 
ATOM   5409 C CE1 . PHE C 1 108 ? -8.713  4.932   3.866   1   38.43  ? 278 PHE B CE1 1 
ATOM   5410 C CE2 . PHE C 1 108 ? -7.129  3.54    4.994   1   39.93  ? 278 PHE B CE2 1 
ATOM   5411 C CZ  . PHE C 1 108 ? -8.122  3.687   4.048   1   38.37  ? 278 PHE B CZ  1 
ATOM   5412 N N   . VAL C 1 109 ? -5.129  9.745   7.139   1   45.42  ? 279 VAL B N   1 
ATOM   5413 C CA  . VAL C 1 109 ? -5.081  11.063  7.751   1   48.09  ? 279 VAL B CA  1 
ATOM   5414 C C   . VAL C 1 109 ? -4.747  12.12   6.7     1   51.3   ? 279 VAL B C   1 
ATOM   5415 O O   . VAL C 1 109 ? -5.214  13.26   6.773   1   51.91  ? 279 VAL B O   1 
ATOM   5416 C CB  . VAL C 1 109 ? -4.052  11.084  8.894   1   49.49  ? 279 VAL B CB  1 
ATOM   5417 C CG1 . VAL C 1 109 ? -3.577  12.49   9.249   1   51.35  ? 279 VAL B CG1 1 
ATOM   5418 C CG2 . VAL C 1 109 ? -4.616  10.399  10.12   1   49.15  ? 279 VAL B CG2 1 
ATOM   5419 N N   . TYR C 1 110 ? -3.886  11.724  5.762   1   54.36  ? 280 TYR B N   1 
ATOM   5420 C CA  . TYR C 1 110 ? -3.317  12.618  4.774   1   57.47  ? 280 TYR B CA  1 
ATOM   5421 C C   . TYR C 1 110 ? -4.369  13.035  3.747   1   57.45  ? 280 TYR B C   1 
ATOM   5422 O O   . TYR C 1 110 ? -4.353  14.181  3.305   1   63.96  ? 280 TYR B O   1 
ATOM   5423 C CB  . TYR C 1 110 ? -2.095  11.959  4.139   1   60.42  ? 280 TYR B CB  1 
ATOM   5424 C CG  . TYR C 1 110 ? -1.55   12.72   2.943   1   69.41  ? 280 TYR B CG  1 
ATOM   5425 C CD1 . TYR C 1 110 ? -0.76   13.858  3.122   1   72.86  ? 280 TYR B CD1 1 
ATOM   5426 C CD2 . TYR C 1 110 ? -1.834  12.302  1.636   1   72.21  ? 280 TYR B CD2 1 
ATOM   5427 C CE1 . TYR C 1 110 ? -0.244  14.55   2.035   1   75.86  ? 280 TYR B CE1 1 
ATOM   5428 C CE2 . TYR C 1 110 ? -1.329  12.992  0.543   1   75.18  ? 280 TYR B CE2 1 
ATOM   5429 C CZ  . TYR C 1 110 ? -0.536  14.116  0.746   1   78.43  ? 280 TYR B CZ  1 
ATOM   5430 O OH  . TYR C 1 110 ? -0.067  14.787  -0.348  1   78.34  ? 280 TYR B OH  1 
ATOM   5431 N N   . ILE C 1 111 ? -5.282  12.128  3.373   1   53.01  ? 281 ILE B N   1 
ATOM   5432 C CA  . ILE C 1 111 ? -6.262  12.432  2.336   1   51.3   ? 281 ILE B CA  1 
ATOM   5433 C C   . ILE C 1 111 ? -7.414  13.257  2.893   1   51.76  ? 281 ILE B C   1 
ATOM   5434 O O   . ILE C 1 111 ? -8.339  13.58   2.15    1   51.37  ? 281 ILE B O   1 
ATOM   5435 C CB  . ILE C 1 111 ? -6.835  11.175  1.653   1   49.47  ? 281 ILE B CB  1 
ATOM   5436 C CG1 . ILE C 1 111 ? -7.34   10.156  2.668   1   46.97  ? 281 ILE B CG1 1 
ATOM   5437 C CG2 . ILE C 1 111 ? -5.851  10.57   0.655   1   50.69  ? 281 ILE B CG2 1 
ATOM   5438 C CD1 . ILE C 1 111 ? -8.667  9.544   2.277   1   43.88  ? 281 ILE B CD1 1 
ATOM   5439 N N   . THR C 1 112 ? -7.394  13.523  4.201   1   53.87  ? 282 THR B N   1 
ATOM   5440 C CA  . THR C 1 112 ? -8.372  14.416  4.792   1   58     ? 282 THR B CA  1 
ATOM   5441 C C   . THR C 1 112 ? -7.789  15.829  4.851   1   66.77  ? 282 THR B C   1 
ATOM   5442 O O   . THR C 1 112 ? -8.197  16.609  5.713   1   69.01  ? 282 THR B O   1 
ATOM   5443 C CB  . THR C 1 112 ? -8.785  13.916  6.18    1   58.96  ? 282 THR B CB  1 
ATOM   5444 O OG1 . THR C 1 112 ? -7.738  14.16   7.124   1   61.01  ? 282 THR B OG1 1 
ATOM   5445 C CG2 . THR C 1 112 ? -9.197  12.454  6.174   1   54.12  ? 282 THR B CG2 1 
ATOM   5446 N N   . ASP C 1 113 ? -6.83   16.138  3.952   1   71.76  ? 283 ASP B N   1 
ATOM   5447 C CA  . ASP C 1 113 ? -6.075  17.39   3.93    1   80.08  ? 283 ASP B CA  1 
ATOM   5448 C C   . ASP C 1 113 ? -5.582  17.823  5.312   1   79.6   ? 283 ASP B C   1 
ATOM   5449 O O   . ASP C 1 113 ? -5.296  19.002  5.516   1   80.02  ? 283 ASP B O   1 
ATOM   5450 C CB  . ASP C 1 113 ? -6.854  18.526  3.278   1   88.91  ? 283 ASP B CB  1 
ATOM   5451 C CG  . ASP C 1 113 ? -7.032  18.413  1.772   1   95.74  ? 283 ASP B CG  1 
ATOM   5452 O OD1 . ASP C 1 113 ? -6.305  17.589  1.157   1   94.78  ? 283 ASP B OD1 1 
ATOM   5453 O OD2 . ASP C 1 113 ? -7.891  19.159  1.23    1   96.72  ? 283 ASP B OD2 1 
ATOM   5454 N N   . ASP C 1 114 ? -5.462  16.873  6.247   1   80.16  ? 284 ASP B N   1 
ATOM   5455 C CA  . ASP C 1 114 ? -5.176  17.183  7.644   1   85.1   ? 284 ASP B CA  1 
ATOM   5456 C C   . ASP C 1 114 ? -6.285  18.028  8.284   1   79     ? 284 ASP B C   1 
ATOM   5457 O O   . ASP C 1 114 ? -5.991  18.892  9.107   1   77.87  ? 284 ASP B O   1 
ATOM   5458 C CB  . ASP C 1 114 ? -3.799  17.812  7.797   1   93.01  ? 284 ASP B CB  1 
ATOM   5459 C CG  . ASP C 1 114 ? -2.623  16.891  7.509   1   92.6   ? 284 ASP B CG  1 
ATOM   5460 O OD1 . ASP C 1 114 ? -2.723  16.066  6.556   1   86.93  ? 284 ASP B OD1 1 
ATOM   5461 O OD2 . ASP C 1 114 ? -1.611  17.032  8.231   1   91.7   ? 284 ASP B OD2 1 
ATOM   5462 N N   . THR C 1 115 ? -7.552  17.756  7.921   1   72.8   ? 285 THR B N   1 
ATOM   5463 C CA  . THR C 1 115 ? -8.726  18.263  8.63    1   69.34  ? 285 THR B CA  1 
ATOM   5464 C C   . THR C 1 115 ? -8.774  17.607  10.018  1   63.92  ? 285 THR B C   1 
ATOM   5465 O O   . THR C 1 115 ? -9.075  18.258  11.011  1   64.03  ? 285 THR B O   1 
ATOM   5466 C CB  . THR C 1 115 ? -10.011 18.006  7.82    1   68.99  ? 285 THR B CB  1 
ATOM   5467 O OG1 . THR C 1 115 ? -9.767  18.048  6.42    1   69.27  ? 285 THR B OG1 1 
ATOM   5468 C CG2 . THR C 1 115 ? -11.145 18.986  8.073   1   67.42  ? 285 THR B CG2 1 
ATOM   5469 N N   . TYR C 1 116 ? -8.452  16.305  10.076  1   59.27  ? 286 TYR B N   1 
ATOM   5470 C CA  . TYR C 1 116 ? -8.52   15.509  11.29   1   55.04  ? 286 TYR B CA  1 
ATOM   5471 C C   . TYR C 1 116 ? -7.165  14.89   11.627  1   54.22  ? 286 TYR B C   1 
ATOM   5472 O O   . TYR C 1 116 ? -6.358  14.629  10.742  1   54.04  ? 286 TYR B O   1 
ATOM   5473 C CB  . TYR C 1 116 ? -9.437  14.32   11.03   1   51.46  ? 286 TYR B CB  1 
ATOM   5474 C CG  . TYR C 1 116 ? -10.796 14.692  10.464  1   50.29  ? 286 TYR B CG  1 
ATOM   5475 C CD1 . TYR C 1 116 ? -11.691 15.462  11.2    1   50.46  ? 286 TYR B CD1 1 
ATOM   5476 C CD2 . TYR C 1 116 ? -11.185 14.248  9.201   1   47.95  ? 286 TYR B CD2 1 
ATOM   5477 C CE1 . TYR C 1 116 ? -12.931 15.799  10.681  1   49.71  ? 286 TYR B CE1 1 
ATOM   5478 C CE2 . TYR C 1 116 ? -12.42  14.586  8.672   1   46.26  ? 286 TYR B CE2 1 
ATOM   5479 C CZ  . TYR C 1 116 ? -13.299 15.357  9.418   1   47.66  ? 286 TYR B CZ  1 
ATOM   5480 O OH  . TYR C 1 116 ? -14.539 15.673  8.933   1   47.2   ? 286 TYR B OH  1 
ATOM   5481 N N   . THR C 1 117 ? -6.952  14.62   12.924  1   53.49  ? 287 THR B N   1 
ATOM   5482 C CA  . THR C 1 117 ? -5.727  14.012  13.422  1   53.49  ? 287 THR B CA  1 
ATOM   5483 C C   . THR C 1 117 ? -5.826  12.498  13.295  1   51.61  ? 287 THR B C   1 
ATOM   5484 O O   . THR C 1 117 ? -6.896  11.965  13.03   1   48.51  ? 287 THR B O   1 
ATOM   5485 C CB  . THR C 1 117 ? -5.469  14.378  14.881  1   55.52  ? 287 THR B CB  1 
ATOM   5486 O OG1 . THR C 1 117 ? -6.587  13.834  15.568  1   54.54  ? 287 THR B OG1 1 
ATOM   5487 C CG2 . THR C 1 117 ? -5.325  15.87   15.119  1   57.86  ? 287 THR B CG2 1 
ATOM   5488 N N   . LYS C 1 118 ? -4.693  11.82   13.534  1   54.03  ? 288 LYS B N   1 
ATOM   5489 C CA  . LYS C 1 118 ? -4.595  10.363  13.543  1   52.23  ? 288 LYS B CA  1 
ATOM   5490 C C   . LYS C 1 118 ? -5.425  9.797   14.692  1   51.87  ? 288 LYS B C   1 
ATOM   5491 O O   . LYS C 1 118 ? -6.11   8.796   14.482  1   49.38  ? 288 LYS B O   1 
ATOM   5492 C CB  . LYS C 1 118 ? -3.129  9.929   13.654  1   54.34  ? 288 LYS B CB  1 
ATOM   5493 C CG  . LYS C 1 118 ? -2.774  8.453   13.737  1   54.31  ? 288 LYS B CG  1 
ATOM   5494 C CD  . LYS C 1 118 ? -1.25   8.275   13.734  1   58.03  ? 288 LYS B CD  1 
ATOM   5495 C CE  . LYS C 1 118 ? -0.624  6.912   13.897  1   60.45  ? 288 LYS B CE  1 
ATOM   5496 N NZ  . LYS C 1 118 ? -1.088  6.11    15.043  1   63.26  ? 288 LYS B NZ  1 
ATOM   5497 N N   . LYS C 1 119 ? -5.372  10.454  15.872  1   53.23  ? 289 LYS B N   1 
ATOM   5498 C CA  . LYS C 1 119 ? -6.174  10.057  17.02   1   53.16  ? 289 LYS B CA  1 
ATOM   5499 C C   . LYS C 1 119 ? -7.679  10.112  16.722  1   51.12  ? 289 LYS B C   1 
ATOM   5500 O O   . LYS C 1 119 ? -8.421  9.18    16.999  1   50.61  ? 289 LYS B O   1 
ATOM   5501 C CB  . LYS C 1 119 ? -5.845  10.863  18.272  1   56.84  ? 289 LYS B CB  1 
ATOM   5502 C CG  . LYS C 1 119 ? -7.066  10.939  19.165  1   60.21  ? 289 LYS B CG  1 
ATOM   5503 C CD  . LYS C 1 119 ? -6.797  11.206  20.647  1   67.16  ? 289 LYS B CD  1 
ATOM   5504 C CE  . LYS C 1 119 ? -8.057  11.435  21.461  1   69.16  ? 289 LYS B CE  1 
ATOM   5505 N NZ  . LYS C 1 119 ? -7.757  11.527  22.895  1   70.4   ? 289 LYS B NZ  1 
ATOM   5506 N N   . GLN C 1 120 ? -8.149  11.201  16.127  1   50.72  ? 290 GLN B N   1 
ATOM   5507 C CA  . GLN C 1 120 ? -9.562  11.306  15.802  1   48.85  ? 290 GLN B CA  1 
ATOM   5508 C C   . GLN C 1 120 ? -10.034 10.138  14.917  1   46.47  ? 290 GLN B C   1 
ATOM   5509 O O   . GLN C 1 120 ? -11.177 9.687   15.03   1   45.3   ? 290 GLN B O   1 
ATOM   5510 C CB  . GLN C 1 120 ? -9.842  12.619  15.073  1   48.12  ? 290 GLN B CB  1 
ATOM   5511 C CG  . GLN C 1 120 ? -9.878  13.841  15.97   1   51.03  ? 290 GLN B CG  1 
ATOM   5512 C CD  . GLN C 1 120 ? -10.161 15.073  15.153  1   51.82  ? 290 GLN B CD  1 
ATOM   5513 O OE1 . GLN C 1 120 ? -9.352  15.49   14.32   1   53.12  ? 290 GLN B OE1 1 
ATOM   5514 N NE2 . GLN C 1 120 ? -11.323 15.66   15.365  1   51.41  ? 290 GLN B NE2 1 
ATOM   5515 N N   . VAL C 1 121 ? -9.159  9.66    14.02   1   44.77  ? 291 VAL B N   1 
ATOM   5516 C CA  . VAL C 1 121 ? -9.533  8.639   13.059  1   41.51  ? 291 VAL B CA  1 
ATOM   5517 C C   . VAL C 1 121 ? -9.65   7.288   13.763  1   40.59  ? 291 VAL B C   1 
ATOM   5518 O O   . VAL C 1 121 ? -10.575 6.53    13.476  1   38.98  ? 291 VAL B O   1 
ATOM   5519 C CB  . VAL C 1 121 ? -8.567  8.597   11.86   1   40.7   ? 291 VAL B CB  1 
ATOM   5520 C CG1 . VAL C 1 121 ? -8.752  7.345   10.998  1   37.66  ? 291 VAL B CG1 1 
ATOM   5521 C CG2 . VAL C 1 121 ? -8.684  9.867   11.027  1   40.59  ? 291 VAL B CG2 1 
ATOM   5522 N N   . LEU C 1 122 ? -8.724  7.011   14.687  1   41.41  ? 292 LEU B N   1 
ATOM   5523 C CA  . LEU C 1 122 ? -8.685  5.738   15.381  1   41.54  ? 292 LEU B CA  1 
ATOM   5524 C C   . LEU C 1 122 ? -9.836  5.624   16.368  1   42.93  ? 292 LEU B C   1 
ATOM   5525 O O   . LEU C 1 122 ? -10.358 4.525   16.544  1   42.42  ? 292 LEU B O   1 
ATOM   5526 C CB  . LEU C 1 122 ? -7.348  5.611   16.1    1   42.92  ? 292 LEU B CB  1 
ATOM   5527 C CG  . LEU C 1 122 ? -6.118  5.54    15.196  1   42.19  ? 292 LEU B CG  1 
ATOM   5528 C CD1 . LEU C 1 122 ? -4.876  5.207   16.029  1   43.92  ? 292 LEU B CD1 1 
ATOM   5529 C CD2 . LEU C 1 122 ? -6.362  4.575   14.037  1   39.01  ? 292 LEU B CD2 1 
ATOM   5530 N N   . ARG C 1 123 ? -10.181 6.743   17.029  1   45.97  ? 293 ARG B N   1 
ATOM   5531 C CA  . ARG C 1 123 ? -11.256 6.789   18.018  1   48.05  ? 293 ARG B CA  1 
ATOM   5532 C C   . ARG C 1 123 ? -12.595 6.577   17.309  1   45.83  ? 293 ARG B C   1 
ATOM   5533 O O   . ARG C 1 123 ? -13.482 5.888   17.828  1   46.07  ? 293 ARG B O   1 
ATOM   5534 C CB  . ARG C 1 123 ? -11.328 8.105   18.799  1   51.48  ? 293 ARG B CB  1 
ATOM   5535 C CG  . ARG C 1 123 ? -10.128 8.666   19.548  1   57.98  ? 293 ARG B CG  1 
ATOM   5536 C CD  . ARG C 1 123 ? -9.764  8.048   20.898  1   66.23  ? 293 ARG B CD  1 
ATOM   5537 N NE  . ARG C 1 123 ? -10.907 7.827   21.792  1   76.14  ? 293 ARG B NE  1 
ATOM   5538 C CZ  . ARG C 1 123 ? -10.845 7.544   23.104  1   82.85  ? 293 ARG B CZ  1 
ATOM   5539 N NH1 . ARG C 1 123 ? -11.937 7.144   23.727  1   82.54  ? 293 ARG B NH1 1 
ATOM   5540 N NH2 . ARG C 1 123 ? -9.704  7.607   23.784  1   85.12  ? 293 ARG B NH2 1 
ATOM   5541 N N   . MET C 1 124 ? -12.734 7.182   16.117  1   43.54  ? 294 MET B N   1 
ATOM   5542 C CA  . MET C 1 124 ? -13.934 7.028   15.314  1   40.98  ? 294 MET B CA  1 
ATOM   5543 C C   . MET C 1 124 ? -14.02  5.59    14.811  1   40.63  ? 294 MET B C   1 
ATOM   5544 O O   . MET C 1 124 ? -15.117 5.051   14.678  1   40.99  ? 294 MET B O   1 
ATOM   5545 C CB  . MET C 1 124 ? -13.943 8.013   14.144  1   39.22  ? 294 MET B CB  1 
ATOM   5546 C CG  . MET C 1 124 ? -15.14  7.89    13.196  1   36.22  ? 294 MET B CG  1 
ATOM   5547 S SD  . MET C 1 124 ? -16.734 8.355   13.895  1   35.72  ? 294 MET B SD  1 
ATOM   5548 C CE  . MET C 1 124 ? -16.486 10.126  14.104  1   38.18  ? 294 MET B CE  1 
ATOM   5549 N N   . GLU C 1 125 ? -12.857 4.97    14.555  1   40.95  ? 295 GLU B N   1 
ATOM   5550 C CA  . GLU C 1 125 ? -12.775 3.58    14.131  1   39.32  ? 295 GLU B CA  1 
ATOM   5551 C C   . GLU C 1 125 ? -13.443 2.69    15.184  1   40.47  ? 295 GLU B C   1 
ATOM   5552 O O   . GLU C 1 125 ? -14.271 1.85    14.846  1   39.83  ? 295 GLU B O   1 
ATOM   5553 C CB  . GLU C 1 125 ? -11.341 3.175   13.773  1   39.04  ? 295 GLU B CB  1 
ATOM   5554 C CG  . GLU C 1 125 ? -11.159 1.657   13.704  1   38.54  ? 295 GLU B CG  1 
ATOM   5555 C CD  . GLU C 1 125 ? -9.813  1.127   13.251  1   38.56  ? 295 GLU B CD  1 
ATOM   5556 O OE1 . GLU C 1 125 ? -8.988  0.787   14.131  1   40.13  ? 295 GLU B OE1 1 
ATOM   5557 O OE2 . GLU C 1 125 ? -9.595  1.065   12.019  1   37.41  ? 295 GLU B OE2 1 
ATOM   5558 N N   . HIS C 1 126 ? -13.09  2.885   16.46   1   43.44  ? 296 HIS B N   1 
ATOM   5559 C CA  . HIS C 1 126 ? -13.72  2.163   17.555  1   46.67  ? 296 HIS B CA  1 
ATOM   5560 C C   . HIS C 1 126 ? -15.232 2.371   17.6    1   45.39  ? 296 HIS B C   1 
ATOM   5561 O O   . HIS C 1 126 ? -15.996 1.425   17.807  1   43.95  ? 296 HIS B O   1 
ATOM   5562 C CB  . HIS C 1 126 ? -13.295 2.749   18.896  1   54.21  ? 296 HIS B CB  1 
ATOM   5563 C CG  . HIS C 1 126 ? -12.188 2.012   19.524  1   63.27  ? 296 HIS B CG  1 
ATOM   5564 N ND1 . HIS C 1 126 ? -10.997 1.678   18.914  1   66.7   ? 296 HIS B ND1 1 
ATOM   5565 C CD2 . HIS C 1 126 ? -12.113 1.579   20.778  1   71.56  ? 296 HIS B CD2 1 
ATOM   5566 C CE1 . HIS C 1 126 ? -10.232 1.045   19.789  1   74.71  ? 296 HIS B CE1 1 
ATOM   5567 N NE2 . HIS C 1 126 ? -10.897 0.962   20.927  1   80.13  ? 296 HIS B NE2 1 
ATOM   5568 N N   . LEU C 1 127 ? -15.642 3.642   17.483  1   44.33  ? 297 LEU B N   1 
ATOM   5569 C CA  . LEU C 1 127 ? -17.029 4.033   17.625  1   42.32  ? 297 LEU B CA  1 
ATOM   5570 C C   . LEU C 1 127 ? -17.847 3.394   16.505  1   39.28  ? 297 LEU B C   1 
ATOM   5571 O O   . LEU C 1 127 ? -18.949 2.911   16.745  1   39.63  ? 297 LEU B O   1 
ATOM   5572 C CB  . LEU C 1 127 ? -17.114 5.557   17.6    1   42.79  ? 297 LEU B CB  1 
ATOM   5573 C CG  . LEU C 1 127 ? -18.523 6.145   17.699  1   42.2   ? 297 LEU B CG  1 
ATOM   5574 C CD1 . LEU C 1 127 ? -19.05  5.966   19.089  1   43.42  ? 297 LEU B CD1 1 
ATOM   5575 C CD2 . LEU C 1 127 ? -18.534 7.604   17.334  1   42.9   ? 297 LEU B CD2 1 
ATOM   5576 N N   . VAL C 1 128 ? -17.318 3.411   15.282  1   36.38  ? 298 VAL B N   1 
ATOM   5577 C CA  . VAL C 1 128 ? -17.973 2.726   14.183  1   33.83  ? 298 VAL B CA  1 
ATOM   5578 C C   . VAL C 1 128 ? -18.08  1.232   14.503  1   33.8   ? 298 VAL B C   1 
ATOM   5579 O O   . VAL C 1 128 ? -19.156 0.652   14.335  1   34.44  ? 298 VAL B O   1 
ATOM   5580 C CB  . VAL C 1 128 ? -17.282 2.999   12.833  1   31.89  ? 298 VAL B CB  1 
ATOM   5581 C CG1 . VAL C 1 128 ? -17.819 2.096   11.723  1   29.23  ? 298 VAL B CG1 1 
ATOM   5582 C CG2 . VAL C 1 128 ? -17.37  4.469   12.419  1   31.61  ? 298 VAL B CG2 1 
ATOM   5583 N N   . LEU C 1 129 ? -16.995 0.624   15.01   1   33.48  ? 299 LEU B N   1 
ATOM   5584 C CA  . LEU C 1 129 ? -16.992 -0.798  15.323  1   32.43  ? 299 LEU B CA  1 
ATOM   5585 C C   . LEU C 1 129 ? -17.998 -1.081  16.426  1   33.6   ? 299 LEU B C   1 
ATOM   5586 O O   . LEU C 1 129 ? -18.639 -2.13   16.417  1   32.9   ? 299 LEU B O   1 
ATOM   5587 C CB  . LEU C 1 129 ? -15.614 -1.296  15.743  1   32.88  ? 299 LEU B CB  1 
ATOM   5588 C CG  . LEU C 1 129 ? -14.584 -1.554  14.641  1   31.67  ? 299 LEU B CG  1 
ATOM   5589 C CD1 . LEU C 1 129 ? -13.209 -1.786  15.23   1   32.1   ? 299 LEU B CD1 1 
ATOM   5590 C CD2 . LEU C 1 129 ? -15.006 -2.713  13.766  1   29.76  ? 299 LEU B CD2 1 
ATOM   5591 N N   . LYS C 1 130 ? -18.081 -0.153  17.391  1   35.15  ? 300 LYS B N   1 
ATOM   5592 C CA  . LYS C 1 130 ? -19.023 -0.267  18.496  1   36.23  ? 300 LYS B CA  1 
ATOM   5593 C C   . LYS C 1 130 ? -20.447 -0.183  17.947  1   34.9   ? 300 LYS B C   1 
ATOM   5594 O O   . LYS C 1 130 ? -21.321 -0.921  18.351  1   35.12  ? 300 LYS B O   1 
ATOM   5595 C CB  . LYS C 1 130 ? -18.766 0.797   19.571  1   38.47  ? 300 LYS B CB  1 
ATOM   5596 C CG  . LYS C 1 130 ? -19.917 0.987   20.574  1   40.36  ? 300 LYS B CG  1 
ATOM   5597 C CD  . LYS C 1 130 ? -19.804 2.084   21.632  1   42.46  ? 300 LYS B CD  1 
ATOM   5598 C CE  . LYS C 1 130 ? -21.1   2.518   22.246  1   42.82  ? 300 LYS B CE  1 
ATOM   5599 N NZ  . LYS C 1 130 ? -20.843 3.475   23.333  1   45.03  ? 300 LYS B NZ  1 
ATOM   5600 N N   . VAL C 1 131 ? -20.691 0.733   17.021  1   34.2   ? 301 VAL B N   1 
ATOM   5601 C CA  . VAL C 1 131 ? -22.053 1.014   16.622  1   34.3   ? 301 VAL B CA  1 
ATOM   5602 C C   . VAL C 1 131 ? -22.55  -0.107  15.711  1   33.37  ? 301 VAL B C   1 
ATOM   5603 O O   . VAL C 1 131 ? -23.731 -0.441  15.716  1   33.32  ? 301 VAL B O   1 
ATOM   5604 C CB  . VAL C 1 131 ? -22.126 2.409   15.966  1   34.11  ? 301 VAL B CB  1 
ATOM   5605 C CG1 . VAL C 1 131 ? -23.337 2.597   15.047  1   32.65  ? 301 VAL B CG1 1 
ATOM   5606 C CG2 . VAL C 1 131 ? -22.062 3.503   17.02   1   35.62  ? 301 VAL B CG2 1 
ATOM   5607 N N   . LEU C 1 132 ? -21.642 -0.698  14.936  1   32.65  ? 302 LEU B N   1 
ATOM   5608 C CA  . LEU C 1 132 ? -22.039 -1.748  14.016  1   31.53  ? 302 LEU B CA  1 
ATOM   5609 C C   . LEU C 1 132 ? -21.979 -3.113  14.709  1   32.8   ? 302 LEU B C   1 
ATOM   5610 O O   . LEU C 1 132 ? -22.365 -4.113  14.095  1   32.62  ? 302 LEU B O   1 
ATOM   5611 C CB  . LEU C 1 132 ? -21.145 -1.686  12.778  1   28.93  ? 302 LEU B CB  1 
ATOM   5612 C CG  . LEU C 1 132 ? -21.185 -0.375  11.991  1   27.57  ? 302 LEU B CG  1 
ATOM   5613 C CD1 . LEU C 1 132 ? -20.484 -0.547  10.652  1   26.15  ? 302 LEU B CD1 1 
ATOM   5614 C CD2 . LEU C 1 132 ? -22.605 0.078   11.769  1   27.2   ? 302 LEU B CD2 1 
ATOM   5615 N N   . ALA C 1 133 ? -21.503 -3.125  15.971  1   33.73  ? 303 ALA B N   1 
ATOM   5616 C CA  . ALA C 1 133 ? -21.233 -4.32   16.765  1   34.74  ? 303 ALA B CA  1 
ATOM   5617 C C   . ALA C 1 133 ? -20.305 -5.277  16.019  1   34.46  ? 303 ALA B C   1 
ATOM   5618 O O   . ALA C 1 133 ? -20.453 -6.487  16.098  1   33.97  ? 303 ALA B O   1 
ATOM   5619 C CB  . ALA C 1 133 ? -22.52  -4.996  17.17   1   34.26  ? 303 ALA B CB  1 
ATOM   5620 N N   . PHE C 1 134 ? -19.383 -4.702  15.246  1   35.02  ? 304 PHE B N   1 
ATOM   5621 C CA  . PHE C 1 134 ? -18.405 -5.45   14.486  1   35.03  ? 304 PHE B CA  1 
ATOM   5622 C C   . PHE C 1 134 ? -19.029 -6.181  13.306  1   35.75  ? 304 PHE B C   1 
ATOM   5623 O O   . PHE C 1 134 ? -18.287 -6.9    12.643  1   39.24  ? 304 PHE B O   1 
ATOM   5624 C CB  . PHE C 1 134 ? -17.65  -6.476  15.325  1   34.37  ? 304 PHE B CB  1 
ATOM   5625 C CG  . PHE C 1 134 ? -16.317 -6.003  15.868  1   35.44  ? 304 PHE B CG  1 
ATOM   5626 C CD1 . PHE C 1 134 ? -15.173 -6.11   15.09   1   34.49  ? 304 PHE B CD1 1 
ATOM   5627 C CD2 . PHE C 1 134 ? -16.201 -5.506  17.163  1   38.29  ? 304 PHE B CD2 1 
ATOM   5628 C CE1 . PHE C 1 134 ? -13.942 -5.719  15.587  1   36.14  ? 304 PHE B CE1 1 
ATOM   5629 C CE2 . PHE C 1 134 ? -14.968 -5.118  17.668  1   39.24  ? 304 PHE B CE2 1 
ATOM   5630 C CZ  . PHE C 1 134 ? -13.843 -5.225  16.877  1   38.61  ? 304 PHE B CZ  1 
ATOM   5631 N N   . ASP C 1 135 ? -20.338 -6.007  13.04   1   34.97  ? 305 ASP B N   1 
ATOM   5632 C CA  . ASP C 1 135 ? -21.009 -6.805  12.017  1   34.73  ? 305 ASP B CA  1 
ATOM   5633 C C   . ASP C 1 135 ? -20.559 -6.304  10.649  1   32.86  ? 305 ASP B C   1 
ATOM   5634 O O   . ASP C 1 135 ? -21.307 -5.587  10      1   34.68  ? 305 ASP B O   1 
ATOM   5635 C CB  . ASP C 1 135 ? -22.506 -6.941  12.284  1   38.12  ? 305 ASP B CB  1 
ATOM   5636 C CG  . ASP C 1 135 ? -22.902 -7.768  13.519  1   48.18  ? 305 ASP B CG  1 
ATOM   5637 O OD1 . ASP C 1 135 ? -22.078 -8.593  14.001  1   53.14  ? 305 ASP B OD1 1 
ATOM   5638 O OD2 . ASP C 1 135 ? -24.027 -7.584  14.046  1   49.42  ? 305 ASP B OD2 1 
ATOM   5639 N N   . LEU C 1 136 ? -19.339 -6.676  10.221  1   31.32  ? 306 LEU B N   1 
ATOM   5640 C CA  . LEU C 1 136 ? -18.643 -6.008  9.122   1   29.9   ? 306 LEU B CA  1 
ATOM   5641 C C   . LEU C 1 136 ? -18.773 -6.76   7.803   1   28.37  ? 306 LEU B C   1 
ATOM   5642 O O   . LEU C 1 136 ? -18.603 -6.179  6.754   1   27.55  ? 306 LEU B O   1 
ATOM   5643 C CB  . LEU C 1 136 ? -17.167 -5.831  9.455   1   30.2   ? 306 LEU B CB  1 
ATOM   5644 C CG  . LEU C 1 136 ? -16.828 -4.734  10.462  1   31.93  ? 306 LEU B CG  1 
ATOM   5645 C CD1 . LEU C 1 136 ? -15.388 -4.305  10.264  1   32.8   ? 306 LEU B CD1 1 
ATOM   5646 C CD2 . LEU C 1 136 ? -17.751 -3.539  10.342  1   31.31  ? 306 LEU B CD2 1 
ATOM   5647 N N   . ALA C 1 137 ? -19.031 -8.065  7.857   1   30.64  ? 307 ALA B N   1 
ATOM   5648 C CA  . ALA C 1 137 ? -19.163 -8.887  6.667   1   28.62  ? 307 ALA B CA  1 
ATOM   5649 C C   . ALA C 1 137 ? -20.545 -8.683  6.052   1   27.94  ? 307 ALA B C   1 
ATOM   5650 O O   . ALA C 1 137 ? -21.458 -9.484  6.211   1   30.24  ? 307 ALA B O   1 
ATOM   5651 C CB  . ALA C 1 137 ? -18.905 -10.323 7.061   1   28.63  ? 307 ALA B CB  1 
ATOM   5652 N N   . ALA C 1 138 ? -20.7   -7.57   5.354   1   27.94  ? 308 ALA B N   1 
ATOM   5653 C CA  . ALA C 1 138 ? -22.007 -7.172  4.854   1   29.66  ? 308 ALA B CA  1 
ATOM   5654 C C   . ALA C 1 138 ? -22.096 -7.547  3.388   1   31.11  ? 308 ALA B C   1 
ATOM   5655 O O   . ALA C 1 138 ? -21.107 -7.386  2.67    1   35.12  ? 308 ALA B O   1 
ATOM   5656 C CB  . ALA C 1 138 ? -22.18  -5.673  4.978   1   30.04  ? 308 ALA B CB  1 
ATOM   5657 N N   . PRO C 1 139 ? -23.263 -8.022  2.903   1   29.36  ? 309 PRO B N   1 
ATOM   5658 C CA  . PRO C 1 139 ? -23.453 -8.246  1.469   1   28.74  ? 309 PRO B CA  1 
ATOM   5659 C C   . PRO C 1 139 ? -23.453 -6.909  0.733   1   29.86  ? 309 PRO B C   1 
ATOM   5660 O O   . PRO C 1 139 ? -24.065 -5.952  1.212   1   32.2   ? 309 PRO B O   1 
ATOM   5661 C CB  . PRO C 1 139 ? -24.797 -8.951  1.357   1   28.85  ? 309 PRO B CB  1 
ATOM   5662 C CG  . PRO C 1 139 ? -25.12  -9.382  2.781   1   31.32  ? 309 PRO B CG  1 
ATOM   5663 C CD  . PRO C 1 139 ? -24.433 -8.386  3.705   1   29.99  ? 309 PRO B CD  1 
ATOM   5664 N N   . THR C 1 140 ? -22.736 -6.867  -0.405  1   28.45  ? 310 THR B N   1 
ATOM   5665 C CA  . THR C 1 140 ? -22.611 -5.7    -1.28   1   27.66  ? 310 THR B CA  1 
ATOM   5666 C C   . THR C 1 140 ? -23.321 -5.956  -2.612  1   29.47  ? 310 THR B C   1 
ATOM   5667 O O   . THR C 1 140 ? -23.665 -7.101  -2.952  1   30.65  ? 310 THR B O   1 
ATOM   5668 C CB  . THR C 1 140 ? -21.157 -5.338  -1.571  1   25.59  ? 310 THR B CB  1 
ATOM   5669 O OG1 . THR C 1 140 ? -20.581 -6.48   -2.211  1   24.64  ? 310 THR B OG1 1 
ATOM   5670 C CG2 . THR C 1 140 ? -20.384 -4.918  -0.334  1   24.51  ? 310 THR B CG2 1 
ATOM   5671 N N   . ILE C 1 141 ? -23.519 -4.867  -3.367  1   26.51  ? 311 ILE B N   1 
ATOM   5672 C CA  . ILE C 1 141 ? -24.154 -4.991  -4.653  1   28.05  ? 311 ILE B CA  1 
ATOM   5673 C C   . ILE C 1 141 ? -23.278 -5.889  -5.512  1   34.73  ? 311 ILE B C   1 
ATOM   5674 O O   . ILE C 1 141 ? -23.787 -6.634  -6.34   1   44.26  ? 311 ILE B O   1 
ATOM   5675 C CB  . ILE C 1 141 ? -24.353 -3.613  -5.286  1   27.54  ? 311 ILE B CB  1 
ATOM   5676 C CG1 . ILE C 1 141 ? -25.442 -2.838  -4.555  1   28.15  ? 311 ILE B CG1 1 
ATOM   5677 C CG2 . ILE C 1 141 ? -24.63  -3.734  -6.788  1   27.64  ? 311 ILE B CG2 1 
ATOM   5678 C CD1 . ILE C 1 141 ? -25.429 -1.348  -4.854  1   28.58  ? 311 ILE B CD1 1 
ATOM   5679 N N   . ASN C 1 142 ? -21.97  -5.856  -5.263  1   36.07  ? 312 ASN B N   1 
ATOM   5680 C CA  . ASN C 1 142 ? -20.997 -6.642  -6.071  1   36.35  ? 312 ASN B CA  1 
ATOM   5681 C C   . ASN C 1 142 ? -21.046 -8.134  -5.727  1   35.57  ? 312 ASN B C   1 
ATOM   5682 O O   . ASN C 1 142 ? -20.891 -8.932  -6.648  1   36.01  ? 312 ASN B O   1 
ATOM   5683 C CB  . ASN C 1 142 ? -19.584 -6.099  -5.915  1   39.31  ? 312 ASN B CB  1 
ATOM   5684 C CG  . ASN C 1 142 ? -19.36  -4.812  -6.667  1   47.72  ? 312 ASN B CG  1 
ATOM   5685 O OD1 . ASN C 1 142 ? -18.218 -4.363  -6.784  1   56.85  ? 312 ASN B OD1 1 
ATOM   5686 N ND2 . ASN C 1 142 ? -20.418 -4.207  -7.184  1   45.33  ? 312 ASN B ND2 1 
ATOM   5687 N N   . GLN C 1 143 ? -21.242 -8.506  -4.463  1   33.44  ? 313 GLN B N   1 
ATOM   5688 C CA  . GLN C 1 143 ? -21.247 -9.924  -4.168  1   31.71  ? 313 GLN B CA  1 
ATOM   5689 C C   . GLN C 1 143 ? -22.347 -10.625 -4.96   1   31.02  ? 313 GLN B C   1 
ATOM   5690 O O   . GLN C 1 143 ? -22.235 -11.803 -5.293  1   31.15  ? 313 GLN B O   1 
ATOM   5691 C CB  . GLN C 1 143 ? -21.365 -10.115 -2.667  1   31.19  ? 313 GLN B CB  1 
ATOM   5692 C CG  . GLN C 1 143 ? -20.007 -10.024 -1.998  1   32.33  ? 313 GLN B CG  1 
ATOM   5693 C CD  . GLN C 1 143 ? -20.177 -9.962  -0.508  1   35.24  ? 313 GLN B CD  1 
ATOM   5694 O OE1 . GLN C 1 143 ? -20.464 -10.972 0.147   1   43.37  ? 313 GLN B OE1 1 
ATOM   5695 N NE2 . GLN C 1 143 ? -20.014 -8.763  0.035   1   34.37  ? 313 GLN B NE2 1 
ATOM   5696 N N   . PHE C 1 144 ? -23.402 -9.875  -5.29   1   30.74  ? 314 PHE B N   1 
ATOM   5697 C CA  . PHE C 1 144 ? -24.492 -10.429 -6.071  1   30.07  ? 314 PHE B CA  1 
ATOM   5698 C C   . PHE C 1 144 ? -24.134 -10.425 -7.557  1   30.37  ? 314 PHE B C   1 
ATOM   5699 O O   . PHE C 1 144 ? -24.303 -11.446 -8.232  1   30.45  ? 314 PHE B O   1 
ATOM   5700 C CB  . PHE C 1 144 ? -25.761 -9.678  -5.678  1   30.7   ? 314 PHE B CB  1 
ATOM   5701 C CG  . PHE C 1 144 ? -26.358 -10.104 -4.342  1   31.95  ? 314 PHE B CG  1 
ATOM   5702 C CD1 . PHE C 1 144 ? -26.953 -11.364 -4.189  1   30.4   ? 314 PHE B CD1 1 
ATOM   5703 C CD2 . PHE C 1 144 ? -26.352 -9.229  -3.251  1   31.01  ? 314 PHE B CD2 1 
ATOM   5704 C CE1 . PHE C 1 144 ? -27.522 -11.742 -2.973  1   29.69  ? 314 PHE B CE1 1 
ATOM   5705 C CE2 . PHE C 1 144 ? -26.922 -9.621  -2.035  1   30.71  ? 314 PHE B CE2 1 
ATOM   5706 C CZ  . PHE C 1 144 ? -27.518 -10.865 -1.906  1   29.08  ? 314 PHE B CZ  1 
ATOM   5707 N N   . LEU C 1 145 ? -23.604 -9.282  -8.032  1   29.11  ? 315 LEU B N   1 
ATOM   5708 C CA  . LEU C 1 145 ? -23.292 -9.034  -9.433  1   28.82  ? 315 LEU B CA  1 
ATOM   5709 C C   . LEU C 1 145 ? -22.366 -10.122 -9.975  1   29.26  ? 315 LEU B C   1 
ATOM   5710 O O   . LEU C 1 145 ? -22.596 -10.675 -11.052 1   29.39  ? 315 LEU B O   1 
ATOM   5711 C CB  . LEU C 1 145 ? -22.679 -7.642  -9.614  1   28.38  ? 315 LEU B CB  1 
ATOM   5712 C CG  . LEU C 1 145 ? -23.62  -6.473  -9.932  1   28.73  ? 315 LEU B CG  1 
ATOM   5713 C CD1 . LEU C 1 145 ? -22.825 -5.191  -10.053 1   29.54  ? 315 LEU B CD1 1 
ATOM   5714 C CD2 . LEU C 1 145 ? -24.379 -6.669  -11.227 1   29.93  ? 315 LEU B CD2 1 
ATOM   5715 N N   . THR C 1 146 ? -21.309 -10.428 -9.212  1   29.4   ? 316 THR B N   1 
ATOM   5716 C CA  . THR C 1 146 ? -20.328 -11.421 -9.633  1   30.26  ? 316 THR B CA  1 
ATOM   5717 C C   . THR C 1 146 ? -21.029 -12.771 -9.823  1   31.06  ? 316 THR B C   1 
ATOM   5718 O O   . THR C 1 146 ? -20.654 -13.534 -10.71  1   34.99  ? 316 THR B O   1 
ATOM   5719 C CB  . THR C 1 146 ? -19.101 -11.479 -8.713  1   27.46  ? 316 THR B CB  1 
ATOM   5720 O OG1 . THR C 1 146 ? -19.582 -12.017 -7.49   1   28.16  ? 316 THR B OG1 1 
ATOM   5721 C CG2 . THR C 1 146 ? -18.507 -10.118 -8.398  1   25.68  ? 316 THR B CG2 1 
ATOM   5722 N N   . GLN C 1 147 ? -22.062 -13.042 -9.011  1   28.64  ? 317 GLN B N   1 
ATOM   5723 C CA  . GLN C 1 147 ? -22.805 -14.292 -9.087  1   30.13  ? 317 GLN B CA  1 
ATOM   5724 C C   . GLN C 1 147 ? -23.74  -14.307 -10.295 1   31.59  ? 317 GLN B C   1 
ATOM   5725 O O   . GLN C 1 147 ? -23.833 -15.309 -11.008 1   31.15  ? 317 GLN B O   1 
ATOM   5726 C CB  . GLN C 1 147 ? -23.592 -14.52  -7.8    1   29.11  ? 317 GLN B CB  1 
ATOM   5727 C CG  . GLN C 1 147 ? -22.661 -14.79  -6.634  1   31.1   ? 317 GLN B CG  1 
ATOM   5728 C CD  . GLN C 1 147 ? -23.307 -15.334 -5.385  1   33.54  ? 317 GLN B CD  1 
ATOM   5729 O OE1 . GLN C 1 147 ? -22.692 -15.293 -4.312  1   38.45  ? 317 GLN B OE1 1 
ATOM   5730 N NE2 . GLN C 1 147 ? -24.518 -15.859 -5.505  1   31.47  ? 317 GLN B NE2 1 
ATOM   5731 N N   . TYR C 1 148 ? -24.455 -13.194 -10.473 1   32.92  ? 318 TYR B N   1 
ATOM   5732 C CA  . TYR C 1 148 ? -25.278 -12.958 -11.646 1   31.96  ? 318 TYR B CA  1 
ATOM   5733 C C   . TYR C 1 148 ? -24.424 -13.195 -12.886 1   33.7   ? 318 TYR B C   1 
ATOM   5734 O O   . TYR C 1 148 ? -24.895 -13.836 -13.814 1   37.39  ? 318 TYR B O   1 
ATOM   5735 C CB  . TYR C 1 148 ? -25.944 -11.574 -11.627 1   29.77  ? 318 TYR B CB  1 
ATOM   5736 C CG  . TYR C 1 148 ? -26.886 -11.345 -10.451 1   29     ? 318 TYR B CG  1 
ATOM   5737 C CD1 . TYR C 1 148 ? -27.294 -12.393 -9.639  1   29.43  ? 318 TYR B CD1 1 
ATOM   5738 C CD2 . TYR C 1 148 ? -27.373 -10.083 -10.14  1   28.52  ? 318 TYR B CD2 1 
ATOM   5739 C CE1 . TYR C 1 148 ? -28.148 -12.199 -8.565  1   28.65  ? 318 TYR B CE1 1 
ATOM   5740 C CE2 . TYR C 1 148 ? -28.223 -9.872  -9.066  1   27.77  ? 318 TYR B CE2 1 
ATOM   5741 C CZ  . TYR C 1 148 ? -28.607 -10.932 -8.259  1   27.69  ? 318 TYR B CZ  1 
ATOM   5742 O OH  . TYR C 1 148 ? -29.439 -10.779 -7.178  1   25.95  ? 318 TYR B OH  1 
ATOM   5743 N N   . PHE C 1 149 ? -23.169 -12.716 -12.893 1   31.77  ? 319 PHE B N   1 
ATOM   5744 C CA  . PHE C 1 149 ? -22.366 -12.725 -14.11  1   31.6   ? 319 PHE B CA  1 
ATOM   5745 C C   . PHE C 1 149 ? -22.177 -14.14  -14.649 1   31.29  ? 319 PHE B C   1 
ATOM   5746 O O   . PHE C 1 149 ? -21.97  -14.311 -15.837 1   33.93  ? 319 PHE B O   1 
ATOM   5747 C CB  . PHE C 1 149 ? -20.977 -12.103 -13.95  1   32.31  ? 319 PHE B CB  1 
ATOM   5748 C CG  . PHE C 1 149 ? -20.97  -10.605 -13.712 1   30.82  ? 319 PHE B CG  1 
ATOM   5749 C CD1 . PHE C 1 149 ? -22.074 -9.825  -14.042 1   32.01  ? 319 PHE B CD1 1 
ATOM   5750 C CD2 . PHE C 1 149 ? -19.868 -9.991  -13.138 1   29.89  ? 319 PHE B CD2 1 
ATOM   5751 C CE1 . PHE C 1 149 ? -22.075 -8.458  -13.784 1   32.34  ? 319 PHE B CE1 1 
ATOM   5752 C CE2 . PHE C 1 149 ? -19.868 -8.627  -12.9   1   29.99  ? 319 PHE B CE2 1 
ATOM   5753 C CZ  . PHE C 1 149 ? -20.972 -7.863  -13.222 1   31.53  ? 319 PHE B CZ  1 
ATOM   5754 N N   . LEU C 1 150 ? -22.236 -15.123 -13.774 1   30.92  ? 320 LEU B N   1 
ATOM   5755 C CA  . LEU C 1 150 ? -21.939 -16.509 -14.186 1   32.13  ? 320 LEU B CA  1 
ATOM   5756 C C   . LEU C 1 150 ? -23.104 -17.062 -15.001 1   34.63  ? 320 LEU B C   1 
ATOM   5757 O O   . LEU C 1 150 ? -23.017 -18.201 -15.465 1   38.25  ? 320 LEU B O   1 
ATOM   5758 C CB  . LEU C 1 150 ? -21.679 -17.269 -12.891 1   30.84  ? 320 LEU B CB  1 
ATOM   5759 C CG  . LEU C 1 150 ? -20.538 -16.753 -12.012 1   30.07  ? 320 LEU B CG  1 
ATOM   5760 C CD1 . LEU C 1 150 ? -20.504 -17.518 -10.704 1   30.59  ? 320 LEU B CD1 1 
ATOM   5761 C CD2 . LEU C 1 150 ? -19.216 -16.879 -12.732 1   28.23  ? 320 LEU B CD2 1 
ATOM   5762 N N   . HIS C 1 151 ? -24.13  -16.251 -15.202 1   34.81  ? 321 HIS B N   1 
ATOM   5763 C CA  . HIS C 1 151 ? -25.334 -16.689 -15.945 1   38.43  ? 321 HIS B CA  1 
ATOM   5764 C C   . HIS C 1 151 ? -25.324 -16.053 -17.333 1   44.47  ? 321 HIS B C   1 
ATOM   5765 O O   . HIS C 1 151 ? -26.38  -15.959 -17.968 1   50.48  ? 321 HIS B O   1 
ATOM   5766 C CB  . HIS C 1 151 ? -26.586 -16.293 -15.166 1   37.27  ? 321 HIS B CB  1 
ATOM   5767 C CG  . HIS C 1 151 ? -26.753 -17.008 -13.874 1   37.76  ? 321 HIS B CG  1 
ATOM   5768 N ND1 . HIS C 1 151 ? -27.799 -17.873 -13.659 1   37.68  ? 321 HIS B ND1 1 
ATOM   5769 C CD2 . HIS C 1 151 ? -26.045 -16.996 -12.747 1   36.08  ? 321 HIS B CD2 1 
ATOM   5770 C CE1 . HIS C 1 151 ? -27.712 -18.363 -12.438 1   37.01  ? 321 HIS B CE1 1 
ATOM   5771 N NE2 . HIS C 1 151 ? -26.653 -17.846 -11.867 1   35.19  ? 321 HIS B NE2 1 
ATOM   5772 N N   . GLN C 1 152 ? -24.15  -15.639 -17.79  1   45.69  ? 322 GLN B N   1 
ATOM   5773 C CA  . GLN C 1 152 ? -24.029 -14.972 -19.101 1   49.81  ? 322 GLN B CA  1 
ATOM   5774 C C   . GLN C 1 152 ? -23.768 -16.012 -20.191 1   59.38  ? 322 GLN B C   1 
ATOM   5775 O O   . GLN C 1 152 ? -23.035 -16.977 -19.923 1   66.58  ? 322 GLN B O   1 
ATOM   5776 C CB  . GLN C 1 152 ? -22.889 -13.967 -19.01  1   46.57  ? 322 GLN B CB  1 
ATOM   5777 C CG  . GLN C 1 152 ? -23.317 -12.57  -18.588 1   50.04  ? 322 GLN B CG  1 
ATOM   5778 C CD  . GLN C 1 152 ? -22.194 -11.568 -18.701 1   55.71  ? 322 GLN B CD  1 
ATOM   5779 O OE1 . GLN C 1 152 ? -22.072 -10.849 -19.697 1   60.32  ? 322 GLN B OE1 1 
ATOM   5780 N NE2 . GLN C 1 152 ? -21.349 -11.527 -17.683 1   51.81  ? 322 GLN B NE2 1 
ATOM   5781 N N   . GLN C 1 153 ? -24.35  -15.806 -21.374 1   66.48  ? 323 GLN B N   1 
ATOM   5782 C CA  . GLN C 1 153 ? -24.139 -16.732 -22.513 1   70.76  ? 323 GLN B CA  1 
ATOM   5783 C C   . GLN C 1 153 ? -23.878 -15.919 -23.792 1   68.41  ? 323 GLN B C   1 
ATOM   5784 O O   . GLN C 1 153 ? -24.855 -15.556 -24.469 1   68.85  ? 323 GLN B O   1 
ATOM   5785 C CB  . GLN C 1 153 ? -25.375 -17.608 -22.679 1   79.27  ? 323 GLN B CB  1 
ATOM   5786 C CG  . GLN C 1 153 ? -25.062 -19.045 -23.076 1   92.39  ? 323 GLN B CG  1 
ATOM   5787 C CD  . GLN C 1 153 ? -24.748 -19.923 -21.886 1   99.17  ? 323 GLN B CD  1 
ATOM   5788 O OE1 . GLN C 1 153 ? -25.592 -20.151 -21.013 1   88.93  ? 323 GLN B OE1 1 
ATOM   5789 N NE2 . GLN C 1 153 ? -23.52  -20.418 -21.84  1   102.2  ? 323 GLN B NE2 1 
ATOM   5790 N N   . PRO C 1 154 ? -22.612 -15.617 -24.149 1   61.45  ? 324 PRO B N   1 
ATOM   5791 C CA  . PRO C 1 154 ? -21.487 -15.912 -23.282 1   58.93  ? 324 PRO B CA  1 
ATOM   5792 C C   . PRO C 1 154 ? -21.125 -14.743 -22.4   1   56.83  ? 324 PRO B C   1 
ATOM   5793 O O   . PRO C 1 154 ? -21.874 -13.759 -22.315 1   54.11  ? 324 PRO B O   1 
ATOM   5794 C CB  . PRO C 1 154 ? -20.439 -16.154 -24.334 1   58.04  ? 324 PRO B CB  1 
ATOM   5795 C CG  . PRO C 1 154 ? -20.708 -15.073 -25.346 1   59.14  ? 324 PRO B CG  1 
ATOM   5796 C CD  . PRO C 1 154 ? -22.224 -14.986 -25.392 1   58.66  ? 324 PRO B CD  1 
ATOM   5797 N N   . ALA C 1 155 ? -19.975 -14.84  -21.75  1   54.95  ? 325 ALA B N   1 
ATOM   5798 C CA  . ALA C 1 155 ? -19.543 -13.769 -20.834 1   48.59  ? 325 ALA B CA  1 
ATOM   5799 C C   . ALA C 1 155 ? -19.094 -12.546 -21.621 1   42.87  ? 325 ALA B C   1 
ATOM   5800 O O   . ALA C 1 155 ? -18.246 -12.693 -22.501 1   43.36  ? 325 ALA B O   1 
ATOM   5801 C CB  . ALA C 1 155 ? -18.443 -14.291 -19.959 1   46.14  ? 325 ALA B CB  1 
ATOM   5802 N N   . ASN C 1 156 ? -19.661 -11.387 -21.313 1   38.67  ? 326 ASN B N   1 
ATOM   5803 C CA  . ASN C 1 156 ? -19.217 -10.124 -21.951 1   39.71  ? 326 ASN B CA  1 
ATOM   5804 C C   . ASN C 1 156 ? -18.708 -9.242  -20.823 1   41.69  ? 326 ASN B C   1 
ATOM   5805 O O   . ASN C 1 156 ? -19.469 -8.976  -19.89  1   40.63  ? 326 ASN B O   1 
ATOM   5806 C CB  . ASN C 1 156 ? -20.295 -9.474  -22.807 1   40.27  ? 326 ASN B CB  1 
ATOM   5807 C CG  . ASN C 1 156 ? -19.784 -8.346  -23.663 1   40.82  ? 326 ASN B CG  1 
ATOM   5808 O OD1 . ASN C 1 156 ? -18.646 -7.898  -23.499 1   41.31  ? 326 ASN B OD1 1 
ATOM   5809 N ND2 . ASN C 1 156 ? -20.61  -7.881  -24.586 1   40.96  ? 326 ASN B ND2 1 
ATOM   5810 N N   . CYS C 1 157 ? -17.466 -8.808  -20.934 1   44.35  ? 327 CYS B N   1 
ATOM   5811 C CA  . CYS C 1 157 ? -16.837 -8.012  -19.885 1   46.93  ? 327 CYS B CA  1 
ATOM   5812 C C   . CYS C 1 157 ? -17.269 -6.539  -19.974 1   42.17  ? 327 CYS B C   1 
ATOM   5813 O O   . CYS C 1 157 ? -17.096 -5.779  -19.004 1   36.03  ? 327 CYS B O   1 
ATOM   5814 C CB  . CYS C 1 157 ? -15.324 -8.174  -19.983 1   53.74  ? 327 CYS B CB  1 
ATOM   5815 S SG  . CYS C 1 157 ? -14.68  -7.594  -21.58  1   70     ? 327 CYS B SG  1 
ATOM   5816 N N   . LYS C 1 158 ? -17.808 -6.162  -21.154 1   40.21  ? 328 LYS B N   1 
ATOM   5817 C CA  . LYS C 1 158 ? -18.456 -4.881  -21.399 1   39.44  ? 328 LYS B CA  1 
ATOM   5818 C C   . LYS C 1 158 ? -19.74  -4.814  -20.563 1   39.43  ? 328 LYS B C   1 
ATOM   5819 O O   . LYS C 1 158 ? -20.034 -3.792  -19.931 1   38.21  ? 328 LYS B O   1 
ATOM   5820 C CB  . LYS C 1 158 ? -18.768 -4.728  -22.891 1   40.69  ? 328 LYS B CB  1 
ATOM   5821 C CG  . LYS C 1 158 ? -17.595 -4.721  -23.862 1   43.99  ? 328 LYS B CG  1 
ATOM   5822 C CD  . LYS C 1 158 ? -16.739 -3.469  -23.696 1   50.59  ? 328 LYS B CD  1 
ATOM   5823 C CE  . LYS C 1 158 ? -15.528 -3.311  -24.592 1   55.37  ? 328 LYS B CE  1 
ATOM   5824 N NZ  . LYS C 1 158 ? -15.8   -3.164  -26.023 1   61.8   ? 328 LYS B NZ  1 
ATOM   5825 N N   . VAL C 1 159 ? -20.496 -5.924  -20.553 1   38.79  ? 329 VAL B N   1 
ATOM   5826 C CA  . VAL C 1 159 ? -21.68  -6.081  -19.722 1   34.88  ? 329 VAL B CA  1 
ATOM   5827 C C   . VAL C 1 159 ? -21.258 -5.987  -18.265 1   33.48  ? 329 VAL B C   1 
ATOM   5828 O O   . VAL C 1 159 ? -21.871 -5.244  -17.514 1   34.39  ? 329 VAL B O   1 
ATOM   5829 C CB  . VAL C 1 159 ? -22.465 -7.379  -20.008 1   33.92  ? 329 VAL B CB  1 
ATOM   5830 C CG1 . VAL C 1 159 ? -23.567 -7.628  -18.989 1   32.19  ? 329 VAL B CG1 1 
ATOM   5831 C CG2 . VAL C 1 159 ? -23.048 -7.395  -21.414 1   33.88  ? 329 VAL B CG2 1 
ATOM   5832 N N   . GLU C 1 160 ? -20.202 -6.727  -17.882 1   34.15  ? 330 GLU B N   1 
ATOM   5833 C CA  . GLU C 1 160 ? -19.785 -6.83   -16.483 1   29.73  ? 330 GLU B CA  1 
ATOM   5834 C C   . GLU C 1 160 ? -19.354 -5.453  -16.008 1   28.71  ? 330 GLU B C   1 
ATOM   5835 O O   . GLU C 1 160 ? -19.797 -5.005  -14.967 1   28.49  ? 330 GLU B O   1 
ATOM   5836 C CB  . GLU C 1 160 ? -18.684 -7.86   -16.249 1   28.48  ? 330 GLU B CB  1 
ATOM   5837 C CG  . GLU C 1 160 ? -19.097 -9.271  -16.648 1   31.54  ? 330 GLU B CG  1 
ATOM   5838 C CD  . GLU C 1 160 ? -18.143 -10.412 -16.309 1   33.73  ? 330 GLU B CD  1 
ATOM   5839 O OE1 . GLU C 1 160 ? -17.322 -10.271 -15.367 1   32.44  ? 330 GLU B OE1 1 
ATOM   5840 O OE2 . GLU C 1 160 ? -18.208 -11.447 -17.021 1   34.77  ? 330 GLU B OE2 1 
ATOM   5841 N N   . SER C 1 161 ? -18.503 -4.784  -16.796 1   30.22  ? 331 SER B N   1 
ATOM   5842 C CA  . SER C 1 161 ? -17.988 -3.483  -16.401 1   30.02  ? 331 SER B CA  1 
ATOM   5843 C C   . SER C 1 161 ? -19.146 -2.498  -16.318 1   32.1   ? 331 SER B C   1 
ATOM   5844 O O   . SER C 1 161 ? -19.188 -1.69   -15.401 1   33.29  ? 331 SER B O   1 
ATOM   5845 C CB  . SER C 1 161 ? -16.893 -2.992  -17.305 1   29.32  ? 331 SER B CB  1 
ATOM   5846 O OG  . SER C 1 161 ? -15.674 -3.682  -17.072 1   27.75  ? 331 SER B OG  1 
ATOM   5847 N N   . LEU C 1 162 ? -20.097 -2.591  -17.254 1   33.75  ? 332 LEU B N   1 
ATOM   5848 C CA  . LEU C 1 162 ? -21.237 -1.687  -17.244 1   34.18  ? 332 LEU B CA  1 
ATOM   5849 C C   . LEU C 1 162 ? -22.114 -1.968  -16.022 1   33.79  ? 332 LEU B C   1 
ATOM   5850 O O   . LEU C 1 162 ? -22.657 -1.037  -15.443 1   37.31  ? 332 LEU B O   1 
ATOM   5851 C CB  . LEU C 1 162 ? -22.024 -1.733  -18.557 1   33.21  ? 332 LEU B CB  1 
ATOM   5852 C CG  . LEU C 1 162 ? -23.166 -0.715  -18.715 1   32.55  ? 332 LEU B CG  1 
ATOM   5853 C CD1 . LEU C 1 162 ? -22.748 0.717   -18.422 1   31.01  ? 332 LEU B CD1 1 
ATOM   5854 C CD2 . LEU C 1 162 ? -23.76  -0.771  -20.106 1   32.92  ? 332 LEU B CD2 1 
ATOM   5855 N N   . ALA C 1 163 ? -22.242 -3.236  -15.621 1   31.41  ? 333 ALA B N   1 
ATOM   5856 C CA  . ALA C 1 163 ? -23.035 -3.597  -14.457 1   30.68  ? 333 ALA B CA  1 
ATOM   5857 C C   . ALA C 1 163 ? -22.415 -3.028  -13.174 1   32.75  ? 333 ALA B C   1 
ATOM   5858 O O   . ALA C 1 163 ? -23.12  -2.528  -12.299 1   30.73  ? 333 ALA B O   1 
ATOM   5859 C CB  . ALA C 1 163 ? -23.15  -5.096  -14.383 1   29.08  ? 333 ALA B CB  1 
ATOM   5860 N N   . MET C 1 164 ? -21.089 -3.147  -13.071 1   35.28  ? 334 MET B N   1 
ATOM   5861 C CA  . MET C 1 164 ? -20.275 -2.606  -12     1   37.54  ? 334 MET B CA  1 
ATOM   5862 C C   . MET C 1 164 ? -20.526 -1.099  -11.865 1   37.19  ? 334 MET B C   1 
ATOM   5863 O O   . MET C 1 164 ? -20.741 -0.563  -10.771 1   36.9   ? 334 MET B O   1 
ATOM   5864 C CB  . MET C 1 164 ? -18.791 -2.879  -12.321 1   43.49  ? 334 MET B CB  1 
ATOM   5865 C CG  . MET C 1 164 ? -18.255 -4.265  -11.944 1   45.18  ? 334 MET B CG  1 
ATOM   5866 S SD  . MET C 1 164 ? -18.514 -4.521  -10.171 1   61.02  ? 334 MET B SD  1 
ATOM   5867 C CE  . MET C 1 164 ? -18.114 -6.254  -9.932  1   56.37  ? 334 MET B CE  1 
ATOM   5868 N N   . PHE C 1 165 ? -20.487 -0.417  -13.014 1   38.03  ? 335 PHE B N   1 
ATOM   5869 C CA  . PHE C 1 165 ? -20.606 1.028   -13.122 1   37.93  ? 335 PHE B CA  1 
ATOM   5870 C C   . PHE C 1 165 ? -21.953 1.499   -12.585 1   38.94  ? 335 PHE B C   1 
ATOM   5871 O O   . PHE C 1 165 ? -22.001 2.45    -11.805 1   40.64  ? 335 PHE B O   1 
ATOM   5872 C CB  . PHE C 1 165 ? -20.434 1.449   -14.584 1   34.13  ? 335 PHE B CB  1 
ATOM   5873 C CG  . PHE C 1 165 ? -20.778 2.898   -14.875 1   32.95  ? 335 PHE B CG  1 
ATOM   5874 C CD1 . PHE C 1 165 ? -20.067 3.936   -14.287 1   33.81  ? 335 PHE B CD1 1 
ATOM   5875 C CD2 . PHE C 1 165 ? -21.79  3.22    -15.758 1   33.37  ? 335 PHE B CD2 1 
ATOM   5876 C CE1 . PHE C 1 165 ? -20.368 5.259   -14.573 1   34.85  ? 335 PHE B CE1 1 
ATOM   5877 C CE2 . PHE C 1 165 ? -22.061 4.542   -16.074 1   35.27  ? 335 PHE B CE2 1 
ATOM   5878 C CZ  . PHE C 1 165 ? -21.354 5.558   -15.485 1   35.72  ? 335 PHE B CZ  1 
ATOM   5879 N N   . LEU C 1 166 ? -23.035 0.846   -13.035 1   37.28  ? 336 LEU B N   1 
ATOM   5880 C CA  . LEU C 1 166 ? -24.393 1.253   -12.711 1   35.83  ? 336 LEU B CA  1 
ATOM   5881 C C   . LEU C 1 166 ? -24.652 1.021   -11.232 1   35.28  ? 336 LEU B C   1 
ATOM   5882 O O   . LEU C 1 166 ? -25.326 1.822   -10.589 1   35.7   ? 336 LEU B O   1 
ATOM   5883 C CB  . LEU C 1 166 ? -25.392 0.498   -13.586 1   33.62  ? 336 LEU B CB  1 
ATOM   5884 C CG  . LEU C 1 166 ? -25.335 0.816   -15.082 1   32.16  ? 336 LEU B CG  1 
ATOM   5885 C CD1 . LEU C 1 166 ? -26.072 -0.255  -15.849 1   32.13  ? 336 LEU B CD1 1 
ATOM   5886 C CD2 . LEU C 1 166 ? -25.932 2.174   -15.356 1   31.68  ? 336 LEU B CD2 1 
ATOM   5887 N N   . GLY C 1 167 ? -24.123 -0.092  -10.717 1   36.73  ? 337 GLY B N   1 
ATOM   5888 C CA  . GLY C 1 167 ? -24.199 -0.412  -9.297  1   38.56  ? 337 GLY B CA  1 
ATOM   5889 C C   . GLY C 1 167 ? -23.493 0.627   -8.42   1   39.27  ? 337 GLY B C   1 
ATOM   5890 O O   . GLY C 1 167 ? -23.967 0.92    -7.32   1   37.85  ? 337 GLY B O   1 
ATOM   5891 N N   . GLU C 1 168 ? -22.351 1.152   -8.896  1   37.36  ? 338 GLU B N   1 
ATOM   5892 C CA  . GLU C 1 168 ? -21.636 2.193   -8.176  1   35.79  ? 338 GLU B CA  1 
ATOM   5893 C C   . GLU C 1 168 ? -22.444 3.483   -8.173  1   39.18  ? 338 GLU B C   1 
ATOM   5894 O O   . GLU C 1 168 ? -22.513 4.174   -7.152  1   42.77  ? 338 GLU B O   1 
ATOM   5895 C CB  . GLU C 1 168 ? -20.251 2.456   -8.755  1   32.78  ? 338 GLU B CB  1 
ATOM   5896 C CG  . GLU C 1 168 ? -19.174 2.082   -7.749  1   32.78  ? 338 GLU B CG  1 
ATOM   5897 C CD  . GLU C 1 168 ? -17.852 1.828   -8.404  1   33.07  ? 338 GLU B CD  1 
ATOM   5898 O OE1 . GLU C 1 168 ? -17.124 2.818   -8.646  1   31.73  ? 338 GLU B OE1 1 
ATOM   5899 O OE2 . GLU C 1 168 ? -17.601 0.627   -8.692  1   33.45  ? 338 GLU B OE2 1 
ATOM   5900 N N   . LEU C 1 169 ? -23.043 3.784   -9.332  1   38.6   ? 339 LEU B N   1 
ATOM   5901 C CA  . LEU C 1 169 ? -23.829 4.988   -9.509  1   37.65  ? 339 LEU B CA  1 
ATOM   5902 C C   . LEU C 1 169 ? -24.896 5.039   -8.424  1   37.87  ? 339 LEU B C   1 
ATOM   5903 O O   . LEU C 1 169 ? -25.17  6.106   -7.885  1   40.97  ? 339 LEU B O   1 
ATOM   5904 C CB  . LEU C 1 169 ? -24.416 5.056   -10.916 1   37.08  ? 339 LEU B CB  1 
ATOM   5905 C CG  . LEU C 1 169 ? -23.497 5.588   -12.023 1   36.88  ? 339 LEU B CG  1 
ATOM   5906 C CD1 . LEU C 1 169 ? -24.265 5.864   -13.315 1   36.19  ? 339 LEU B CD1 1 
ATOM   5907 C CD2 . LEU C 1 169 ? -22.752 6.83    -11.567 1   36.99  ? 339 LEU B CD2 1 
ATOM   5908 N N   . SER C 1 170 ? -25.468 3.876   -8.086  1   37.07  ? 340 SER B N   1 
ATOM   5909 C CA  . SER C 1 170 ? -26.568 3.825   -7.126  1   35.64  ? 340 SER B CA  1 
ATOM   5910 C C   . SER C 1 170 ? -26.116 4.257   -5.728  1   34.03  ? 340 SER B C   1 
ATOM   5911 O O   . SER C 1 170 ? -26.943 4.777   -4.996  1   39.71  ? 340 SER B O   1 
ATOM   5912 C CB  . SER C 1 170 ? -27.29  2.487   -7.123  1   32.81  ? 340 SER B CB  1 
ATOM   5913 O OG  . SER C 1 170 ? -26.494 1.461   -6.552  1   31.94  ? 340 SER B OG  1 
ATOM   5914 N N   . LEU C 1 171 ? -24.828 4.11    -5.378  1   30.61  ? 341 LEU B N   1 
ATOM   5915 C CA  . LEU C 1 171 ? -24.342 4.398   -4.031  1   31.25  ? 341 LEU B CA  1 
ATOM   5916 C C   . LEU C 1 171 ? -24.436 5.891   -3.689  1   34.58  ? 341 LEU B C   1 
ATOM   5917 O O   . LEU C 1 171 ? -24.533 6.266   -2.513  1   34.35  ? 341 LEU B O   1 
ATOM   5918 C CB  . LEU C 1 171 ? -22.896 3.942   -3.875  1   30.37  ? 341 LEU B CB  1 
ATOM   5919 C CG  . LEU C 1 171 ? -22.618 2.454   -4.069  1   30.7   ? 341 LEU B CG  1 
ATOM   5920 C CD1 . LEU C 1 171 ? -21.135 2.2     -4.294  1   29.03  ? 341 LEU B CD1 1 
ATOM   5921 C CD2 . LEU C 1 171 ? -23.135 1.645   -2.888  1   29.8   ? 341 LEU B CD2 1 
ATOM   5922 N N   . ILE C 1 172 ? -24.39  6.743   -4.722  1   34.85  ? 342 ILE B N   1 
ATOM   5923 C CA  . ILE C 1 172 ? -24.196 8.172   -4.553  1   34.7   ? 342 ILE B CA  1 
ATOM   5924 C C   . ILE C 1 172 ? -25.481 8.79    -3.998  1   35.55  ? 342 ILE B C   1 
ATOM   5925 O O   . ILE C 1 172 ? -25.407 9.751   -3.234  1   36.03  ? 342 ILE B O   1 
ATOM   5926 C CB  . ILE C 1 172 ? -23.79  8.81    -5.901  1   34.22  ? 342 ILE B CB  1 
ATOM   5927 C CG1 . ILE C 1 172 ? -22.505 8.253   -6.474  1   31.46  ? 342 ILE B CG1 1 
ATOM   5928 C CG2 . ILE C 1 172 ? -23.696 10.323  -5.767  1   37.14  ? 342 ILE B CG2 1 
ATOM   5929 C CD1 . ILE C 1 172 ? -21.253 8.968   -5.997  1   31.75  ? 342 ILE B CD1 1 
ATOM   5930 N N   . ASP C 1 173 ? -26.611 8.273   -4.484  1   35.88  ? 343 ASP B N   1 
ATOM   5931 C CA  . ASP C 1 173 ? -27.927 8.886   -4.185  1   38.06  ? 343 ASP B CA  1 
ATOM   5932 C C   . ASP C 1 173 ? -28.806 8.005   -3.302  1   42.11  ? 343 ASP B C   1 
ATOM   5933 O O   . ASP C 1 173 ? -29.377 7.044   -3.823  1   44.24  ? 343 ASP B O   1 
ATOM   5934 C CB  . ASP C 1 173 ? -28.619 9.19    -5.499  1   37.52  ? 343 ASP B CB  1 
ATOM   5935 C CG  . ASP C 1 173 ? -27.755 9.85    -6.559  1   40.79  ? 343 ASP B CG  1 
ATOM   5936 O OD1 . ASP C 1 173 ? -27.378 11.015  -6.352  1   40.72  ? 343 ASP B OD1 1 
ATOM   5937 O OD2 . ASP C 1 173 ? -27.471 9.194   -7.577  1   43.22  ? 343 ASP B OD2 1 
ATOM   5938 N N   . ALA C 1 174 ? -28.97  8.381   -2.031  1   41.3   ? 344 ALA B N   1 
ATOM   5939 C CA  . ALA C 1 174 ? -29.827 7.639   -1.083  1   36.74  ? 344 ALA B CA  1 
ATOM   5940 C C   . ALA C 1 174 ? -31.264 7.663   -1.573  1   39.92  ? 344 ALA B C   1 
ATOM   5941 O O   . ALA C 1 174 ? -32.034 6.769   -1.205  1   39.84  ? 344 ALA B O   1 
ATOM   5942 C CB  . ALA C 1 174 ? -29.708 8.29    0.25    1   33.65  ? 344 ALA B CB  1 
ATOM   5943 N N   . ASP C 1 175 ? -31.617 8.68    -2.357  1   47.34  ? 345 ASP B N   1 
ATOM   5944 C CA  . ASP C 1 175 ? -32.967 8.726   -2.976  1   48.83  ? 345 ASP B CA  1 
ATOM   5945 C C   . ASP C 1 175 ? -32.807 8.462   -4.468  1   47.06  ? 345 ASP B C   1 
ATOM   5946 O O   . ASP C 1 175 ? -32.295 9.336   -5.17   1   47.8   ? 345 ASP B O   1 
ATOM   5947 C CB  . ASP C 1 175 ? -33.684 10.038  -2.725  1   49.97  ? 345 ASP B CB  1 
ATOM   5948 C CG  . ASP C 1 175 ? -35.14  10.072  -3.163  1   53.86  ? 345 ASP B CG  1 
ATOM   5949 O OD1 . ASP C 1 175 ? -35.56  11.105  -3.717  1   54.95  ? 345 ASP B OD1 1 
ATOM   5950 O OD2 . ASP C 1 175 ? -35.837 9.064   -2.948  1   56.39  ? 345 ASP B OD2 1 
ATOM   5951 N N   . PRO C 1 176 ? -33.218 7.286   -4.97   1   46.11  ? 346 PRO B N   1 
ATOM   5952 C CA  . PRO C 1 176 ? -34.01  6.363   -4.171  1   45.06  ? 346 PRO B CA  1 
ATOM   5953 C C   . PRO C 1 176 ? -33.423 5.019   -3.896  1   43.52  ? 346 PRO B C   1 
ATOM   5954 O O   . PRO C 1 176 ? -34.184 4.064   -3.815  1   46.82  ? 346 PRO B O   1 
ATOM   5955 C CB  . PRO C 1 176 ? -34.994 6.23    -5.302  1   46.6   ? 346 PRO B CB  1 
ATOM   5956 C CG  . PRO C 1 176 ? -34.128 5.889   -6.482  1   44.58  ? 346 PRO B CG  1 
ATOM   5957 C CD  . PRO C 1 176 ? -32.989 6.859   -6.328  1   44.2   ? 346 PRO B CD  1 
ATOM   5958 N N   . TYR C 1 177 ? -32.118 4.926   -3.702  1   40.33  ? 347 TYR B N   1 
ATOM   5959 C CA  . TYR C 1 177 ? -31.505 3.575   -3.651  1   38.65  ? 347 TYR B CA  1 
ATOM   5960 C C   . TYR C 1 177 ? -31.489 2.983   -2.262  1   38.62  ? 347 TYR B C   1 
ATOM   5961 O O   . TYR C 1 177 ? -31.288 1.772   -2.146  1   41.5   ? 347 TYR B O   1 
ATOM   5962 C CB  . TYR C 1 177 ? -30.173 3.744   -4.381  1   37.62  ? 347 TYR B CB  1 
ATOM   5963 C CG  . TYR C 1 177 ? -30.384 4.041   -5.856  1   40.19  ? 347 TYR B CG  1 
ATOM   5964 C CD1 . TYR C 1 177 ? -31.098 3.167   -6.665  1   36.37  ? 347 TYR B CD1 1 
ATOM   5965 C CD2 . TYR C 1 177 ? -29.896 5.21    -6.421  1   44.87  ? 347 TYR B CD2 1 
ATOM   5966 C CE1 . TYR C 1 177 ? -31.307 3.442   -8.004  1   36.81  ? 347 TYR B CE1 1 
ATOM   5967 C CE2 . TYR C 1 177 ? -30.095 5.495   -7.758  1   42.93  ? 347 TYR B CE2 1 
ATOM   5968 C CZ  . TYR C 1 177 ? -30.803 4.61    -8.546  1   43.16  ? 347 TYR B CZ  1 
ATOM   5969 O OH  . TYR C 1 177 ? -30.992 4.917   -9.853  1   45.23  ? 347 TYR B OH  1 
ATOM   5970 N N   . LEU C 1 178 ? -31.712 3.78    -1.233  1   37.19  ? 348 LEU B N   1 
ATOM   5971 C CA  . LEU C 1 178 ? -31.805 3.145   0.069   1   38.35  ? 348 LEU B CA  1 
ATOM   5972 C C   . LEU C 1 178 ? -33.017 2.217   0.141   1   39.17  ? 348 LEU B C   1 
ATOM   5973 O O   . LEU C 1 178 ? -33.04  1.305   0.963   1   41.95  ? 348 LEU B O   1 
ATOM   5974 C CB  . LEU C 1 178 ? -31.859 4.205   1.167   1   40.06  ? 348 LEU B CB  1 
ATOM   5975 C CG  . LEU C 1 178 ? -30.54  4.909   1.475   1   40.47  ? 348 LEU B CG  1 
ATOM   5976 C CD1 . LEU C 1 178 ? -30.673 5.686   2.782   1   39.99  ? 348 LEU B CD1 1 
ATOM   5977 C CD2 . LEU C 1 178 ? -29.398 3.881   1.526   1   39.08  ? 348 LEU B CD2 1 
ATOM   5978 N N   . LYS C 1 179 ? -34.04  2.469   -0.682  1   39.58  ? 349 LYS B N   1 
ATOM   5979 C CA  . LYS C 1 179 ? -35.271 1.706   -0.573  1   41.01  ? 349 LYS B CA  1 
ATOM   5980 C C   . LYS C 1 179 ? -35.104 0.34    -1.237  1   41.42  ? 349 LYS B C   1 
ATOM   5981 O O   . LYS C 1 179 ? -36.001 -0.494  -1.187  1   46.41  ? 349 LYS B O   1 
ATOM   5982 C CB  . LYS C 1 179 ? -36.457 2.496   -1.133  1   40.14  ? 349 LYS B CB  1 
ATOM   5983 C CG  . LYS C 1 179 ? -36.543 2.528   -2.639  1   41.28  ? 349 LYS B CG  1 
ATOM   5984 C CD  . LYS C 1 179 ? -37.667 3.417   -3.191  1   43.54  ? 349 LYS B CD  1 
ATOM   5985 C CE  . LYS C 1 179 ? -37.664 4.809   -2.622  1   42.8   ? 349 LYS B CE  1 
ATOM   5986 N NZ  . LYS C 1 179 ? -38.701 5.616   -3.258  1   43.93  ? 349 LYS B NZ  1 
ATOM   5987 N N   . TYR C 1 180 ? -33.953 0.119   -1.865  1   38     ? 350 TYR B N   1 
ATOM   5988 C CA  . TYR C 1 180 ? -33.717 -1.131  -2.564  1   37.39  ? 350 TYR B CA  1 
ATOM   5989 C C   . TYR C 1 180 ? -32.551 -1.886  -1.921  1   37.09  ? 350 TYR B C   1 
ATOM   5990 O O   . TYR C 1 180 ? -31.514 -1.297  -1.595  1   35.58  ? 350 TYR B O   1 
ATOM   5991 C CB  . TYR C 1 180 ? -33.446 -0.846  -4.048  1   38.12  ? 350 TYR B CB  1 
ATOM   5992 C CG  . TYR C 1 180 ? -34.533 -0.102  -4.812  1   38.82  ? 350 TYR B CG  1 
ATOM   5993 C CD1 . TYR C 1 180 ? -35.726 -0.732  -5.144  1   39.53  ? 350 TYR B CD1 1 
ATOM   5994 C CD2 . TYR C 1 180 ? -34.36  1.224   -5.211  1   39.28  ? 350 TYR B CD2 1 
ATOM   5995 C CE1 . TYR C 1 180 ? -36.713 -0.069  -5.855  1   41.19  ? 350 TYR B CE1 1 
ATOM   5996 C CE2 . TYR C 1 180 ? -35.338 1.892   -5.932  1   39.07  ? 350 TYR B CE2 1 
ATOM   5997 C CZ  . TYR C 1 180 ? -36.514 1.243   -6.249  1   40.77  ? 350 TYR B CZ  1 
ATOM   5998 O OH  . TYR C 1 180 ? -37.498 1.895   -6.914  1   43.37  ? 350 TYR B OH  1 
ATOM   5999 N N   . LEU C 1 181 ? -32.731 -3.208  -1.785  1   36.93  ? 351 LEU B N   1 
ATOM   6000 C CA  . LEU C 1 181 ? -31.717 -4.122  -1.278  1   36.76  ? 351 LEU B CA  1 
ATOM   6001 C C   . LEU C 1 181 ? -30.578 -4.261  -2.287  1   37.25  ? 351 LEU B C   1 
ATOM   6002 O O   . LEU C 1 181 ? -30.776 -4.087  -3.497  1   37.35  ? 351 LEU B O   1 
ATOM   6003 C CB  . LEU C 1 181 ? -32.328 -5.498  -1.024  1   36.12  ? 351 LEU B CB  1 
ATOM   6004 C CG  . LEU C 1 181 ? -33.36  -5.625  0.099   1   34.43  ? 351 LEU B CG  1 
ATOM   6005 C CD1 . LEU C 1 181 ? -33.796 -7.09   0.201   1   35.1   ? 351 LEU B CD1 1 
ATOM   6006 C CD2 . LEU C 1 181 ? -32.774 -5.164  1.414   1   32.35  ? 351 LEU B CD2 1 
ATOM   6007 N N   . PRO C 1 182 ? -29.354 -4.604  -1.807  1   34.45  ? 352 PRO B N   1 
ATOM   6008 C CA  . PRO C 1 182 ? -28.242 -4.964  -2.689  1   32.39  ? 352 PRO B CA  1 
ATOM   6009 C C   . PRO C 1 182 ? -28.593 -5.978  -3.777  1   32.31  ? 352 PRO B C   1 
ATOM   6010 O O   . PRO C 1 182 ? -28.104 -5.876  -4.894  1   33.2   ? 352 PRO B O   1 
ATOM   6011 C CB  . PRO C 1 182 ? -27.22  -5.548  -1.691  1   31.08  ? 352 PRO B CB  1 
ATOM   6012 C CG  . PRO C 1 182 ? -27.457 -4.757  -0.436  1   30.18  ? 352 PRO B CG  1 
ATOM   6013 C CD  . PRO C 1 182 ? -28.963 -4.595  -0.387  1   31.96  ? 352 PRO B CD  1 
ATOM   6014 N N   . SER C 1 183 ? -29.423 -6.978  -3.465  1   31.92  ? 353 SER B N   1 
ATOM   6015 C CA  . SER C 1 183 ? -29.659 -8.038  -4.436  1   30.45  ? 353 SER B CA  1 
ATOM   6016 C C   . SER C 1 183 ? -30.527 -7.514  -5.586  1   32.51  ? 353 SER B C   1 
ATOM   6017 O O   . SER C 1 183 ? -30.5   -8.055  -6.69   1   32.28  ? 353 SER B O   1 
ATOM   6018 C CB  . SER C 1 183 ? -30.281 -9.248  -3.778  1   27.7   ? 353 SER B CB  1 
ATOM   6019 O OG  . SER C 1 183 ? -31.545 -8.953  -3.218  1   25.94  ? 353 SER B OG  1 
ATOM   6020 N N   . VAL C 1 184 ? -31.322 -6.473  -5.3    1   31.28  ? 354 VAL B N   1 
ATOM   6021 C CA  . VAL C 1 184 ? -32.281 -5.947  -6.251  1   32.04  ? 354 VAL B CA  1 
ATOM   6022 C C   . VAL C 1 184 ? -31.598 -4.968  -7.207  1   33.06  ? 354 VAL B C   1 
ATOM   6023 O O   . VAL C 1 184 ? -31.863 -5.013  -8.408  1   35.39  ? 354 VAL B O   1 
ATOM   6024 C CB  . VAL C 1 184 ? -33.48  -5.323  -5.516  1   31.53  ? 354 VAL B CB  1 
ATOM   6025 C CG1 . VAL C 1 184 ? -34.327 -4.445  -6.435  1   30.64  ? 354 VAL B CG1 1 
ATOM   6026 C CG2 . VAL C 1 184 ? -34.323 -6.393  -4.82   1   29.43  ? 354 VAL B CG2 1 
ATOM   6027 N N   . ILE C 1 185 ? -30.729 -4.094  -6.67   1   30.99  ? 355 ILE B N   1 
ATOM   6028 C CA  . ILE C 1 185 ? -29.968 -3.128  -7.454  1   29.35  ? 355 ILE B CA  1 
ATOM   6029 C C   . ILE C 1 185 ? -28.931 -3.827  -8.336  1   31.57  ? 355 ILE B C   1 
ATOM   6030 O O   . ILE C 1 185 ? -28.575 -3.321  -9.4    1   34.05  ? 355 ILE B O   1 
ATOM   6031 C CB  . ILE C 1 185 ? -29.278 -2.09   -6.553  1   26.62  ? 355 ILE B CB  1 
ATOM   6032 C CG1 . ILE C 1 185 ? -30.261 -1.374  -5.62   1   25.62  ? 355 ILE B CG1 1 
ATOM   6033 C CG2 . ILE C 1 185 ? -28.448 -1.12   -7.401  1   25.39  ? 355 ILE B CG2 1 
ATOM   6034 C CD1 . ILE C 1 185 ? -29.605 -0.456  -4.609  1   24.11  ? 355 ILE B CD1 1 
ATOM   6035 N N   . ALA C 1 186 ? -28.394 -4.956  -7.856  1   33.99  ? 356 ALA B N   1 
ATOM   6036 C CA  . ALA C 1 186 ? -27.442 -5.771  -8.602  1   32.44  ? 356 ALA B CA  1 
ATOM   6037 C C   . ALA C 1 186 ? -28.159 -6.425  -9.784  1   32.58  ? 356 ALA B C   1 
ATOM   6038 O O   . ALA C 1 186 ? -27.613 -6.485  -10.874 1   36.47  ? 356 ALA B O   1 
ATOM   6039 C CB  . ALA C 1 186 ? -26.814 -6.79   -7.681  1   29.24  ? 356 ALA B CB  1 
ATOM   6040 N N   . ALA C 1 187 ? -29.402 -6.867  -9.573  1   31.23  ? 357 ALA B N   1 
ATOM   6041 C CA  . ALA C 1 187 ? -30.209 -7.465  -10.624 1   32.31  ? 357 ALA B CA  1 
ATOM   6042 C C   . ALA C 1 187 ? -30.649 -6.41   -11.641 1   32.97  ? 357 ALA B C   1 
ATOM   6043 O O   . ALA C 1 187 ? -30.608 -6.668  -12.837 1   33.32  ? 357 ALA B O   1 
ATOM   6044 C CB  . ALA C 1 187 ? -31.405 -8.168  -10.035 1   30.51  ? 357 ALA B CB  1 
ATOM   6045 N N   . ALA C 1 188 ? -31.104 -5.248  -11.153 1   30.91  ? 358 ALA B N   1 
ATOM   6046 C CA  . ALA C 1 188 ? -31.491 -4.136  -11.994 1   30.93  ? 358 ALA B CA  1 
ATOM   6047 C C   . ALA C 1 188 ? -30.331 -3.73   -12.905 1   33.65  ? 358 ALA B C   1 
ATOM   6048 O O   . ALA C 1 188 ? -30.496 -3.605  -14.136 1   33.11  ? 358 ALA B O   1 
ATOM   6049 C CB  . ALA C 1 188 ? -31.914 -2.999  -11.108 1   29.76  ? 358 ALA B CB  1 
ATOM   6050 N N   . ALA C 1 189 ? -29.155 -3.532  -12.275 1   34.72  ? 359 ALA B N   1 
ATOM   6051 C CA  . ALA C 1 189 ? -27.945 -3.093  -12.961 1   33.81  ? 359 ALA B CA  1 
ATOM   6052 C C   . ALA C 1 189 ? -27.53  -4.113  -14.034 1   34.73  ? 359 ALA B C   1 
ATOM   6053 O O   . ALA C 1 189 ? -27.236 -3.722  -15.17  1   33.9   ? 359 ALA B O   1 
ATOM   6054 C CB  . ALA C 1 189 ? -26.851 -2.795  -11.955 1   28.41  ? 359 ALA B CB  1 
ATOM   6055 N N   . PHE C 1 190 ? -27.528 -5.41   -13.654 1   33.78  ? 360 PHE B N   1 
ATOM   6056 C CA  . PHE C 1 190 ? -27.186 -6.52   -14.532 1   32.07  ? 360 PHE B CA  1 
ATOM   6057 C C   . PHE C 1 190 ? -28.083 -6.508  -15.774 1   34.02  ? 360 PHE B C   1 
ATOM   6058 O O   . PHE C 1 190 ? -27.587 -6.588  -16.894 1   37.54  ? 360 PHE B O   1 
ATOM   6059 C CB  . PHE C 1 190 ? -27.199 -7.881  -13.835 1   29.1   ? 360 PHE B CB  1 
ATOM   6060 C CG  . PHE C 1 190 ? -26.791 -9.003  -14.78  1   30.3   ? 360 PHE B CG  1 
ATOM   6061 C CD1 . PHE C 1 190 ? -25.474 -9.133  -15.213 1   30.26  ? 360 PHE B CD1 1 
ATOM   6062 C CD2 . PHE C 1 190 ? -27.732 -9.906  -15.26  1   31.61  ? 360 PHE B CD2 1 
ATOM   6063 C CE1 . PHE C 1 190 ? -25.11  -10.14  -16.097 1   32.08  ? 360 PHE B CE1 1 
ATOM   6064 C CE2 . PHE C 1 190 ? -27.365 -10.905 -16.155 1   33.54  ? 360 PHE B CE2 1 
ATOM   6065 C CZ  . PHE C 1 190 ? -26.053 -11.032 -16.568 1   32.8   ? 360 PHE B CZ  1 
ATOM   6066 N N   . HIS C 1 191 ? -29.401 -6.393  -15.583 1   32.82  ? 361 HIS B N   1 
ATOM   6067 C CA  . HIS C 1 191 ? -30.335 -6.374  -16.696 1   34.24  ? 361 HIS B CA  1 
ATOM   6068 C C   . HIS C 1 191 ? -30.071 -5.181  -17.621 1   39.43  ? 361 HIS B C   1 
ATOM   6069 O O   . HIS C 1 191 ? -30.065 -5.312  -18.857 1   42.85  ? 361 HIS B O   1 
ATOM   6070 C CB  . HIS C 1 191 ? -31.777 -6.312  -16.193 1   32.04  ? 361 HIS B CB  1 
ATOM   6071 C CG  . HIS C 1 191 ? -32.748 -6.056  -17.301 1   33.15  ? 361 HIS B CG  1 
ATOM   6072 N ND1 . HIS C 1 191 ? -32.991 -6.962  -18.315 1   33.3   ? 361 HIS B ND1 1 
ATOM   6073 C CD2 . HIS C 1 191 ? -33.494 -4.976  -17.577 1   33.4   ? 361 HIS B CD2 1 
ATOM   6074 C CE1 . HIS C 1 191 ? -33.894 -6.46   -19.135 1   34.34  ? 361 HIS B CE1 1 
ATOM   6075 N NE2 . HIS C 1 191 ? -34.217 -5.257  -18.704 1   34.25  ? 361 HIS B NE2 1 
ATOM   6076 N N   . LEU C 1 192 ? -29.877 -4.01   -16.999 1   38.43  ? 362 LEU B N   1 
ATOM   6077 C CA  . LEU C 1 192 ? -29.738 -2.77   -17.737 1   37.24  ? 362 LEU B CA  1 
ATOM   6078 C C   . LEU C 1 192 ? -28.422 -2.758  -18.524 1   37.32  ? 362 LEU B C   1 
ATOM   6079 O O   . LEU C 1 192 ? -28.353 -2.166  -19.612 1   36.7   ? 362 LEU B O   1 
ATOM   6080 C CB  . LEU C 1 192 ? -29.857 -1.634  -16.722 1   35.11  ? 362 LEU B CB  1 
ATOM   6081 C CG  . LEU C 1 192 ? -29.887 -0.217  -17.296 1   35.32  ? 362 LEU B CG  1 
ATOM   6082 C CD1 . LEU C 1 192 ? -31.031 -0.085  -18.289 1   36.06  ? 362 LEU B CD1 1 
ATOM   6083 C CD2 . LEU C 1 192 ? -30.037 0.773   -16.148 1   35.08  ? 362 LEU B CD2 1 
ATOM   6084 N N   . ALA C 1 193 ? -27.389 -3.432  -17.975 1   34.67  ? 363 ALA B N   1 
ATOM   6085 C CA  . ALA C 1 193 ? -26.105 -3.53   -18.658 1   33.65  ? 363 ALA B CA  1 
ATOM   6086 C C   . ALA C 1 193 ? -26.268 -4.408  -19.896 1   35.82  ? 363 ALA B C   1 
ATOM   6087 O O   . ALA C 1 193 ? -25.958 -3.991  -21.016 1   37.53  ? 363 ALA B O   1 
ATOM   6088 C CB  . ALA C 1 193 ? -25.056 -4.058  -17.733 1   29.83  ? 363 ALA B CB  1 
ATOM   6089 N N   . LEU C 1 194 ? -26.832 -5.598  -19.672 1   34.76  ? 364 LEU B N   1 
ATOM   6090 C CA  . LEU C 1 194 ? -27.073 -6.581  -20.71  1   36.08  ? 364 LEU B CA  1 
ATOM   6091 C C   . LEU C 1 194 ? -27.903 -5.997  -21.859 1   37.42  ? 364 LEU B C   1 
ATOM   6092 O O   . LEU C 1 194 ? -27.675 -6.297  -23.033 1   37.09  ? 364 LEU B O   1 
ATOM   6093 C CB  . LEU C 1 194 ? -27.789 -7.747  -20.037 1   35.74  ? 364 LEU B CB  1 
ATOM   6094 C CG  . LEU C 1 194 ? -27.821 -9.042  -20.853 1   39.17  ? 364 LEU B CG  1 
ATOM   6095 C CD1 . LEU C 1 194 ? -26.424 -9.578  -21.175 1   38.14  ? 364 LEU B CD1 1 
ATOM   6096 C CD2 . LEU C 1 194 ? -28.633 -10.084 -20.102 1   41.82  ? 364 LEU B CD2 1 
ATOM   6097 N N   . TYR C 1 195 ? -28.894 -5.18   -21.507 1   38.4   ? 365 TYR B N   1 
ATOM   6098 C CA  . TYR C 1 195 ? -29.811 -4.662  -22.504 1   41     ? 365 TYR B CA  1 
ATOM   6099 C C   . TYR C 1 195 ? -29.077 -3.667  -23.401 1   41.13  ? 365 TYR B C   1 
ATOM   6100 O O   . TYR C 1 195 ? -29.062 -3.825  -24.614 1   41.61  ? 365 TYR B O   1 
ATOM   6101 C CB  . TYR C 1 195 ? -31.025 -4.038  -21.813 1   42.21  ? 365 TYR B CB  1 
ATOM   6102 C CG  . TYR C 1 195 ? -32.095 -3.593  -22.796 1   46.82  ? 365 TYR B CG  1 
ATOM   6103 C CD1 . TYR C 1 195 ? -32.662 -4.506  -23.682 1   49.45  ? 365 TYR B CD1 1 
ATOM   6104 C CD2 . TYR C 1 195 ? -32.506 -2.267  -22.868 1   46.81  ? 365 TYR B CD2 1 
ATOM   6105 C CE1 . TYR C 1 195 ? -33.64  -4.125  -24.584 1   52.04  ? 365 TYR B CE1 1 
ATOM   6106 C CE2 . TYR C 1 195 ? -33.492 -1.877  -23.757 1   50     ? 365 TYR B CE2 1 
ATOM   6107 C CZ  . TYR C 1 195 ? -34.056 -2.803  -24.621 1   54.1   ? 365 TYR B CZ  1 
ATOM   6108 O OH  . TYR C 1 195 ? -35.025 -2.426  -25.519 1   61.17  ? 365 TYR B OH  1 
ATOM   6109 N N   . THR C 1 196 ? -28.457 -2.663  -22.768 1   40.27  ? 366 THR B N   1 
ATOM   6110 C CA  . THR C 1 196 ? -27.624 -1.649  -23.403 1   39.3   ? 366 THR B CA  1 
ATOM   6111 C C   . THR C 1 196 ? -26.622 -2.283  -24.356 1   37.61  ? 366 THR B C   1 
ATOM   6112 O O   . THR C 1 196 ? -26.432 -1.774  -25.441 1   39.85  ? 366 THR B O   1 
ATOM   6113 C CB  . THR C 1 196 ? -26.837 -0.868  -22.349 1   38.92  ? 366 THR B CB  1 
ATOM   6114 O OG1 . THR C 1 196 ? -27.722 -0.298  -21.4   1   40.24  ? 366 THR B OG1 1 
ATOM   6115 C CG2 . THR C 1 196 ? -25.998 0.255   -22.929 1   38.61  ? 366 THR B CG2 1 
ATOM   6116 N N   . VAL C 1 197 ? -25.95  -3.349  -23.92  1   35.87  ? 367 VAL B N   1 
ATOM   6117 C CA  . VAL C 1 197 ? -24.774 -3.861  -24.609 1   36.07  ? 367 VAL B CA  1 
ATOM   6118 C C   . VAL C 1 197 ? -25.165 -4.854  -25.709 1   38.54  ? 367 VAL B C   1 
ATOM   6119 O O   . VAL C 1 197 ? -24.748 -4.688  -26.87  1   40.03  ? 367 VAL B O   1 
ATOM   6120 C CB  . VAL C 1 197 ? -23.75  -4.44   -23.613 1   33.43  ? 367 VAL B CB  1 
ATOM   6121 C CG1 . VAL C 1 197 ? -22.603 -5.164  -24.305 1   33.52  ? 367 VAL B CG1 1 
ATOM   6122 C CG2 . VAL C 1 197 ? -23.194 -3.35   -22.708 1   31.9   ? 367 VAL B CG2 1 
ATOM   6123 N N   . THR C 1 198 ? -25.969 -5.871  -25.334 1   38.16  ? 368 THR B N   1 
ATOM   6124 C CA  . THR C 1 198 ? -26.231 -7.047  -26.165 1   39.99  ? 368 THR B CA  1 
ATOM   6125 C C   . THR C 1 198 ? -27.667 -7.082  -26.705 1   43.15  ? 368 THR B C   1 
ATOM   6126 O O   . THR C 1 198 ? -27.966 -7.825  -27.648 1   44.09  ? 368 THR B O   1 
ATOM   6127 C CB  . THR C 1 198 ? -25.936 -8.327  -25.387 1   37.52  ? 368 THR B CB  1 
ATOM   6128 O OG1 . THR C 1 198 ? -26.873 -8.496  -24.323 1   36.7   ? 368 THR B OG1 1 
ATOM   6129 C CG2 . THR C 1 198 ? -24.557 -8.324  -24.78  1   36.67  ? 368 THR B CG2 1 
ATOM   6130 N N   . GLY C 1 199 ? -28.574 -6.345  -26.053 1   44.1   ? 369 GLY B N   1 
ATOM   6131 C CA  . GLY C 1 199 ? -29.968 -6.348  -26.452 1   48.22  ? 369 GLY B CA  1 
ATOM   6132 C C   . GLY C 1 199 ? -30.803 -7.329  -25.634 1   52.65  ? 369 GLY B C   1 
ATOM   6133 O O   . GLY C 1 199 ? -32.026 -7.265  -25.686 1   57.58  ? 369 GLY B O   1 
ATOM   6134 N N   . GLN C 1 200 ? -30.122 -8.18   -24.87  1   54.31  ? 370 GLN B N   1 
ATOM   6135 C CA  . GLN C 1 200 ? -30.811 -9.274  -24.149 1   56.19  ? 370 GLN B CA  1 
ATOM   6136 C C   . GLN C 1 200 ? -31.347 -8.826  -22.791 1   52.74  ? 370 GLN B C   1 
ATOM   6137 O O   . GLN C 1 200 ? -31.098 -7.681  -22.402 1   53.63  ? 370 GLN B O   1 
ATOM   6138 C CB  . GLN C 1 200 ? -29.82  -10.428 -24.038 1   62.2   ? 370 GLN B CB  1 
ATOM   6139 C CG  . GLN C 1 200 ? -29.139 -10.794 -25.35  1   68.04  ? 370 GLN B CG  1 
ATOM   6140 C CD  . GLN C 1 200 ? -27.894 -11.627 -25.149 1   74.71  ? 370 GLN B CD  1 
ATOM   6141 O OE1 . GLN C 1 200 ? -27.568 -12.038 -24.031 1   81.02  ? 370 GLN B OE1 1 
ATOM   6142 N NE2 . GLN C 1 200 ? -27.185 -11.886 -26.237 1   79.54  ? 370 GLN B NE2 1 
ATOM   6143 N N   . SER C 1 201 ? -32.042 -9.729  -22.1   1   49.79  ? 371 SER B N   1 
ATOM   6144 C CA  . SER C 1 201 ? -32.717 -9.342  -20.841 1   44.68  ? 371 SER B CA  1 
ATOM   6145 C C   . SER C 1 201 ? -32.51  -10.365 -19.723 1   42.16  ? 371 SER B C   1 
ATOM   6146 O O   . SER C 1 201 ? -32.023 -11.465 -20.021 1   41.84  ? 371 SER B O   1 
ATOM   6147 C CB  . SER C 1 201 ? -34.183 -9.146  -21.098 1   44.38  ? 371 SER B CB  1 
ATOM   6148 O OG  . SER C 1 201 ? -34.431 -7.969  -21.851 1   47.26  ? 371 SER B OG  1 
ATOM   6149 N N   . TRP C 1 202 ? -32.875 -9.995  -18.494 1   40.18  ? 372 TRP B N   1 
ATOM   6150 C CA  . TRP C 1 202 ? -32.774 -10.873 -17.304 1   36.72  ? 372 TRP B CA  1 
ATOM   6151 C C   . TRP C 1 202 ? -33.06  -12.321 -17.661 1   39.8   ? 372 TRP B C   1 
ATOM   6152 O O   . TRP C 1 202 ? -34.205 -12.646 -18.009 1   41     ? 372 TRP B O   1 
ATOM   6153 C CB  . TRP C 1 202 ? -33.775 -10.363 -16.264 1   34.7   ? 372 TRP B CB  1 
ATOM   6154 C CG  . TRP C 1 202 ? -33.677 -10.954 -14.884 1   34.17  ? 372 TRP B CG  1 
ATOM   6155 C CD1 . TRP C 1 202 ? -34.641 -11.673 -14.244 1   34.72  ? 372 TRP B CD1 1 
ATOM   6156 C CD2 . TRP C 1 202 ? -32.58  -10.838 -13.953 1   31.32  ? 372 TRP B CD2 1 
ATOM   6157 N NE1 . TRP C 1 202 ? -34.218 -12.029 -12.994 1   33.03  ? 372 TRP B NE1 1 
ATOM   6158 C CE2 . TRP C 1 202 ? -32.962 -11.529 -12.785 1   31.38  ? 372 TRP B CE2 1 
ATOM   6159 C CE3 . TRP C 1 202 ? -31.323 -10.228 -13.993 1   29.7   ? 372 TRP B CE3 1 
ATOM   6160 C CZ2 . TRP C 1 202 ? -32.132 -11.626 -11.673 1   29.44  ? 372 TRP B CZ2 1 
ATOM   6161 C CZ3 . TRP C 1 202 ? -30.505 -10.324 -12.892 1   28.89  ? 372 TRP B CZ3 1 
ATOM   6162 C CH2 . TRP C 1 202 ? -30.902 -11.02  -11.753 1   28.88  ? 372 TRP B CH2 1 
ATOM   6163 N N   . PRO C 1 203 ? -32.067 -13.218 -17.52  1   40.93  ? 373 PRO B N   1 
ATOM   6164 C CA  . PRO C 1 203 ? -32.27  -14.624 -17.828 1   43.08  ? 373 PRO B CA  1 
ATOM   6165 C C   . PRO C 1 203 ? -33.146 -15.397 -16.848 1   43.41  ? 373 PRO B C   1 
ATOM   6166 O O   . PRO C 1 203 ? -33.277 -14.985 -15.691 1   42.56  ? 373 PRO B O   1 
ATOM   6167 C CB  . PRO C 1 203 ? -30.833 -15.134 -17.843 1   43.56  ? 373 PRO B CB  1 
ATOM   6168 C CG  . PRO C 1 203 ? -30.106 -14.245 -16.879 1   42.32  ? 373 PRO B CG  1 
ATOM   6169 C CD  . PRO C 1 203 ? -30.734 -12.887 -17.068 1   39.42  ? 373 PRO B CD  1 
ATOM   6170 N N   . GLU C 1 204 ? -33.747 -16.492 -17.309 1   45.77  ? 374 GLU B N   1 
ATOM   6171 C CA  . GLU C 1 204 ? -34.573 -17.344 -16.421 1   47.9   ? 374 GLU B CA  1 
ATOM   6172 C C   . GLU C 1 204 ? -33.636 -17.957 -15.402 1   42.75  ? 374 GLU B C   1 
ATOM   6173 O O   . GLU C 1 204 ? -34.003 -18.03  -14.235 1   42.2   ? 374 GLU B O   1 
ATOM   6174 C CB  . GLU C 1 204 ? -35.259 -18.474 -17.182 1   53.49  ? 374 GLU B CB  1 
ATOM   6175 C CG  . GLU C 1 204 ? -36.557 -18.945 -16.533 1   59.93  ? 374 GLU B CG  1 
ATOM   6176 C CD  . GLU C 1 204 ? -37.782 -18.078 -16.772 1   69.97  ? 374 GLU B CD  1 
ATOM   6177 O OE1 . GLU C 1 204 ? -37.716 -17.127 -17.577 1   68.81  ? 374 GLU B OE1 1 
ATOM   6178 O OE2 . GLU C 1 204 ? -38.817 -18.364 -16.141 1   68.03  ? 374 GLU B OE2 1 
ATOM   6179 N N   . SER C 1 205 ? -32.482 -18.407 -15.867 1   41.08  ? 375 SER B N   1 
ATOM   6180 C CA  . SER C 1 205 ? -31.449 -18.917 -14.952 1   38.5   ? 375 SER B CA  1 
ATOM   6181 C C   . SER C 1 205 ? -31.398 -17.976 -13.746 1   38.38  ? 375 SER B C   1 
ATOM   6182 O O   . SER C 1 205 ? -31.179 -18.461 -12.629 1   40.05  ? 375 SER B O   1 
ATOM   6183 C CB  . SER C 1 205 ? -30.153 -18.981 -15.682 1   36.22  ? 375 SER B CB  1 
ATOM   6184 O OG  . SER C 1 205 ? -29.709 -17.686 -16.051 1   35.37  ? 375 SER B OG  1 
ATOM   6185 N N   . LEU C 1 206 ? -31.634 -16.686 -13.976 1   36.04  ? 376 LEU B N   1 
ATOM   6186 C CA  . LEU C 1 206 ? -31.549 -15.757 -12.857 1   33.43  ? 376 LEU B CA  1 
ATOM   6187 C C   . LEU C 1 206 ? -32.896 -15.498 -12.182 1   33.84  ? 376 LEU B C   1 
ATOM   6188 O O   . LEU C 1 206 ? -32.917 -15.045 -11.04  1   34.61  ? 376 LEU B O   1 
ATOM   6189 C CB  . LEU C 1 206 ? -30.87  -14.466 -13.297 1   30.82  ? 376 LEU B CB  1 
ATOM   6190 C CG  . LEU C 1 206 ? -29.348 -14.484 -13.176 1   30.23  ? 376 LEU B CG  1 
ATOM   6191 C CD1 . LEU C 1 206 ? -28.785 -13.191 -13.703 1   30.47  ? 376 LEU B CD1 1 
ATOM   6192 C CD2 . LEU C 1 206 ? -28.903 -14.738 -11.728 1   28.29  ? 376 LEU B CD2 1 
ATOM   6193 N N   . VAL C 1 207 ? -34.002 -15.752 -12.893 1   35.14  ? 377 VAL B N   1 
ATOM   6194 C CA  . VAL C 1 207 ? -35.342 -15.799 -12.319 1   36.13  ? 377 VAL B CA  1 
ATOM   6195 C C   . VAL C 1 207 ? -35.415 -16.953 -11.317 1   38.35  ? 377 VAL B C   1 
ATOM   6196 O O   . VAL C 1 207 ? -36.121 -16.847 -10.315 1   39.24  ? 377 VAL B O   1 
ATOM   6197 C CB  . VAL C 1 207 ? -36.431 -15.936 -13.406 1   35.77  ? 377 VAL B CB  1 
ATOM   6198 C CG1 . VAL C 1 207 ? -37.819 -16.148 -12.831 1   36.23  ? 377 VAL B CG1 1 
ATOM   6199 C CG2 . VAL C 1 207 ? -36.447 -14.739 -14.332 1   34.51  ? 377 VAL B CG2 1 
ATOM   6200 N N   . GLN C 1 208 ? -34.699 -18.051 -11.62  1   38.77  ? 378 GLN B N   1 
ATOM   6201 C CA  . GLN C 1 208 ? -34.695 -19.26  -10.818 1   39.93  ? 378 GLN B CA  1 
ATOM   6202 C C   . GLN C 1 208 ? -33.837 -19.057 -9.57   1   42     ? 378 GLN B C   1 
ATOM   6203 O O   . GLN C 1 208 ? -34.2   -19.494 -8.478  1   46.7   ? 378 GLN B O   1 
ATOM   6204 C CB  . GLN C 1 208 ? -34.05  -20.414 -11.577 1   40.04  ? 378 GLN B CB  1 
ATOM   6205 C CG  . GLN C 1 208 ? -34.724 -20.788 -12.884 1   43.85  ? 378 GLN B CG  1 
ATOM   6206 C CD  . GLN C 1 208 ? -36.067 -21.432 -12.665 1   49.79  ? 378 GLN B CD  1 
ATOM   6207 O OE1 . GLN C 1 208 ? -36.919 -21.477 -13.568 1   57.32  ? 378 GLN B OE1 1 
ATOM   6208 N NE2 . GLN C 1 208 ? -36.262 -21.921 -11.447 1   48.08  ? 378 GLN B NE2 1 
ATOM   6209 N N   . LYS C 1 209 ? -32.659 -18.459 -9.759  1   41.12  ? 379 LYS B N   1 
ATOM   6210 C CA  . LYS C 1 209 ? -31.701 -18.28  -8.682  1   37.52  ? 379 LYS B CA  1 
ATOM   6211 C C   . LYS C 1 209 ? -32.292 -17.336 -7.642  1   36.22  ? 379 LYS B C   1 
ATOM   6212 O O   . LYS C 1 209 ? -32.298 -17.668 -6.461  1   35.35  ? 379 LYS B O   1 
ATOM   6213 C CB  . LYS C 1 209 ? -30.42  -17.655 -9.248  1   37.32  ? 379 LYS B CB  1 
ATOM   6214 C CG  . LYS C 1 209 ? -29.312 -17.487 -8.204  1   37.38  ? 379 LYS B CG  1 
ATOM   6215 C CD  . LYS C 1 209 ? -28.115 -16.69  -8.719  1   36.72  ? 379 LYS B CD  1 
ATOM   6216 C CE  . LYS C 1 209 ? -27.024 -16.516 -7.716  1   33.44  ? 379 LYS B CE  1 
ATOM   6217 N NZ  . LYS C 1 209 ? -26.435 -17.792 -7.302  1   32.35  ? 379 LYS B NZ  1 
ATOM   6218 N N   . THR C 1 210 ? -32.845 -16.2   -8.118  1   34.43  ? 380 THR B N   1 
ATOM   6219 C CA  . THR C 1 210 ? -33.175 -15.049 -7.282  1   31.71  ? 380 THR B CA  1 
ATOM   6220 C C   . THR C 1 210 ? -34.67  -14.991 -6.976  1   32.04  ? 380 THR B C   1 
ATOM   6221 O O   . THR C 1 210 ? -35.073 -14.463 -5.939  1   30.91  ? 380 THR B O   1 
ATOM   6222 C CB  . THR C 1 210 ? -32.775 -13.735 -7.954  1   30.25  ? 380 THR B CB  1 
ATOM   6223 O OG1 . THR C 1 210 ? -33.682 -13.489 -9.022  1   31.59  ? 380 THR B OG1 1 
ATOM   6224 C CG2 . THR C 1 210 ? -31.368 -13.715 -8.501  1   28.62  ? 380 THR B CG2 1 
ATOM   6225 N N   . GLY C 1 211 ? -35.487 -15.458 -7.925  1   32.18  ? 381 GLY B N   1 
ATOM   6226 C CA  . GLY C 1 211 ? -36.93  -15.378 -7.777  1   32.64  ? 381 GLY B CA  1 
ATOM   6227 C C   . GLY C 1 211 ? -37.479 -14.019 -8.201  1   32.27  ? 381 GLY B C   1 
ATOM   6228 O O   . GLY C 1 211 ? -38.698 -13.814 -8.191  1   32.33  ? 381 GLY B O   1 
ATOM   6229 N N   . TYR C 1 212 ? -36.57  -13.106 -8.573  1   31.43  ? 382 TYR B N   1 
ATOM   6230 C CA  . TYR C 1 212 ? -36.956 -11.816 -9.122  1   32.19  ? 382 TYR B CA  1 
ATOM   6231 C C   . TYR C 1 212 ? -37.357 -12.002 -10.582 1   35.88  ? 382 TYR B C   1 
ATOM   6232 O O   . TYR C 1 212 ? -36.682 -12.723 -11.323 1   37.02  ? 382 TYR B O   1 
ATOM   6233 C CB  . TYR C 1 212 ? -35.791 -10.824 -9.035  1   29.34  ? 382 TYR B CB  1 
ATOM   6234 C CG  . TYR C 1 212 ? -35.232 -10.575 -7.64   1   28.11  ? 382 TYR B CG  1 
ATOM   6235 C CD1 . TYR C 1 212 ? -35.986 -10.812 -6.491  1   28.86  ? 382 TYR B CD1 1 
ATOM   6236 C CD2 . TYR C 1 212 ? -33.939 -10.11  -7.468  1   26.45  ? 382 TYR B CD2 1 
ATOM   6237 C CE1 . TYR C 1 212 ? -35.473 -10.58  -5.223  1   27.84  ? 382 TYR B CE1 1 
ATOM   6238 C CE2 . TYR C 1 212 ? -33.408 -9.893  -6.207  1   26.25  ? 382 TYR B CE2 1 
ATOM   6239 C CZ  . TYR C 1 212 ? -34.176 -10.124 -5.073  1   26.66  ? 382 TYR B CZ  1 
ATOM   6240 O OH  . TYR C 1 212 ? -33.656 -9.918  -3.826  1   25.42  ? 382 TYR B OH  1 
ATOM   6241 N N   . THR C 1 213 ? -38.438 -11.325 -11     1   40     ? 383 THR B N   1 
ATOM   6242 C CA  . THR C 1 213 ? -38.754 -11.166 -12.422 1   42.35  ? 383 THR B CA  1 
ATOM   6243 C C   . THR C 1 213 ? -38.625 -9.706  -12.843 1   43.54  ? 383 THR B C   1 
ATOM   6244 O O   . THR C 1 213 ? -38.526 -8.815  -11.998 1   43.72  ? 383 THR B O   1 
ATOM   6245 C CB  . THR C 1 213 ? -40.158 -11.668 -12.751 1   42.93  ? 383 THR B CB  1 
ATOM   6246 O OG1 . THR C 1 213 ? -41.063 -10.882 -11.982 1   43.69  ? 383 THR B OG1 1 
ATOM   6247 C CG2 . THR C 1 213 ? -40.317 -13.147 -12.461 1   41.78  ? 383 THR B CG2 1 
ATOM   6248 N N   . LEU C 1 214 ? -38.678 -9.469  -14.159 1   45.14  ? 384 LEU B N   1 
ATOM   6249 C CA  . LEU C 1 214 ? -38.679 -8.107  -14.671 1   44.2   ? 384 LEU B CA  1 
ATOM   6250 C C   . LEU C 1 214 ? -39.836 -7.326  -14.055 1   46.89  ? 384 LEU B C   1 
ATOM   6251 O O   . LEU C 1 214 ? -39.703 -6.131  -13.793 1   47.76  ? 384 LEU B O   1 
ATOM   6252 C CB  . LEU C 1 214 ? -38.728 -8.095  -16.195 1   41.78  ? 384 LEU B CB  1 
ATOM   6253 C CG  . LEU C 1 214 ? -37.381 -8.233  -16.898 1   38.78  ? 384 LEU B CG  1 
ATOM   6254 C CD1 . LEU C 1 214 ? -37.515 -8.027  -18.382 1   38.41  ? 384 LEU B CD1 1 
ATOM   6255 C CD2 . LEU C 1 214 ? -36.455 -7.189  -16.325 1   38.84  ? 384 LEU B CD2 1 
ATOM   6256 N N   . GLU C 1 215 ? -40.957 -8.025  -13.826 1   48.31  ? 385 GLU B N   1 
ATOM   6257 C CA  . GLU C 1 215 ? -42.082 -7.486  -13.078 1   50.85  ? 385 GLU B CA  1 
ATOM   6258 C C   . GLU C 1 215 ? -41.572 -6.923  -11.747 1   46.95  ? 385 GLU B C   1 
ATOM   6259 O O   . GLU C 1 215 ? -41.84  -5.774  -11.421 1   46.22  ? 385 GLU B O   1 
ATOM   6260 C CB  . GLU C 1 215 ? -43.132 -8.592  -12.916 1   57.56  ? 385 GLU B CB  1 
ATOM   6261 C CG  . GLU C 1 215 ? -44.521 -8.105  -12.509 1   64.53  ? 385 GLU B CG  1 
ATOM   6262 C CD  . GLU C 1 215 ? -45.529 -7.94   -13.644 1   71.85  ? 385 GLU B CD  1 
ATOM   6263 O OE1 . GLU C 1 215 ? -45.105 -7.622  -14.788 1   72.22  ? 385 GLU B OE1 1 
ATOM   6264 O OE2 . GLU C 1 215 ? -46.751 -8.081  -13.372 1   72.62  ? 385 GLU B OE2 1 
ATOM   6265 N N   . THR C 1 216 ? -40.818 -7.737  -10.987 1   44.45  ? 386 THR B N   1 
ATOM   6266 C CA  . THR C 1 216 ? -40.323 -7.404  -9.653  1   41.64  ? 386 THR B CA  1 
ATOM   6267 C C   . THR C 1 216 ? -39.352 -6.239  -9.693  1   39.44  ? 386 THR B C   1 
ATOM   6268 O O   . THR C 1 216 ? -39.364 -5.43   -8.768  1   39.36  ? 386 THR B O   1 
ATOM   6269 C CB  . THR C 1 216 ? -39.558 -8.573  -9.034  1   41.1   ? 386 THR B CB  1 
ATOM   6270 O OG1 . THR C 1 216 ? -40.549 -9.551  -8.745  1   43.49  ? 386 THR B OG1 1 
ATOM   6271 C CG2 . THR C 1 216 ? -38.736 -8.175  -7.811  1   39.24  ? 386 THR B CG2 1 
ATOM   6272 N N   . LEU C 1 217 ? -38.456 -6.259  -10.695 1   37.84  ? 387 LEU B N   1 
ATOM   6273 C CA  . LEU C 1 217 ? -37.32  -5.358  -10.84  1   36.49  ? 387 LEU B CA  1 
ATOM   6274 C C   . LEU C 1 217 ? -37.73  -3.997  -11.395 1   37.58  ? 387 LEU B C   1 
ATOM   6275 O O   . LEU C 1 217 ? -36.946 -3.053  -11.331 1   36.85  ? 387 LEU B O   1 
ATOM   6276 C CB  . LEU C 1 217 ? -36.294 -6.003  -11.768 1   34.54  ? 387 LEU B CB  1 
ATOM   6277 C CG  . LEU C 1 217 ? -35.6   -7.239  -11.195 1   33.1   ? 387 LEU B CG  1 
ATOM   6278 C CD1 . LEU C 1 217 ? -34.622 -7.763  -12.228 1   32.2   ? 387 LEU B CD1 1 
ATOM   6279 C CD2 . LEU C 1 217 ? -34.899 -6.943  -9.855  1   30.81  ? 387 LEU B CD2 1 
ATOM   6280 N N   . LYS C 1 218 ? -38.937 -3.911  -11.954 1   38.78  ? 388 LYS B N   1 
ATOM   6281 C CA  . LYS C 1 218 ? -39.347 -2.748  -12.714 1   41.93  ? 388 LYS B CA  1 
ATOM   6282 C C   . LYS C 1 218 ? -39.15  -1.467  -11.902 1   43.46  ? 388 LYS B C   1 
ATOM   6283 O O   . LYS C 1 218 ? -38.509 -0.535  -12.392 1   43.78  ? 388 LYS B O   1 
ATOM   6284 C CB  . LYS C 1 218 ? -40.769 -2.94   -13.249 1   43.95  ? 388 LYS B CB  1 
ATOM   6285 C CG  . LYS C 1 218 ? -41.157 -2.047  -14.406 1   45.85  ? 388 LYS B CG  1 
ATOM   6286 C CD  . LYS C 1 218 ? -42.662 -1.986  -14.647 1   49.54  ? 388 LYS B CD  1 
ATOM   6287 C CE  . LYS C 1 218 ? -43.061 -0.808  -15.501 1   52.3   ? 388 LYS B CE  1 
ATOM   6288 N NZ  . LYS C 1 218 ? -44.491 -0.49   -15.424 1   54.14  ? 388 LYS B NZ  1 
ATOM   6289 N N   . PRO C 1 219 ? -39.692 -1.331  -10.668 1   42.7   ? 389 PRO B N   1 
ATOM   6290 C CA  . PRO C 1 219 ? -39.562 -0.073  -9.923  1   42.62  ? 389 PRO B CA  1 
ATOM   6291 C C   . PRO C 1 219 ? -38.132 0.453   -9.839  1   42.14  ? 389 PRO B C   1 
ATOM   6292 O O   . PRO C 1 219 ? -37.896 1.624   -10.137 1   42.4   ? 389 PRO B O   1 
ATOM   6293 C CB  . PRO C 1 219 ? -40.141 -0.403  -8.547  1   40.79  ? 389 PRO B CB  1 
ATOM   6294 C CG  . PRO C 1 219 ? -41.144 -1.484  -8.843  1   40.65  ? 389 PRO B CG  1 
ATOM   6295 C CD  . PRO C 1 219 ? -40.491 -2.325  -9.944  1   41.22  ? 389 PRO B CD  1 
ATOM   6296 N N   . CYS C 1 220 ? -37.199 -0.427  -9.44   1   42.12  ? 390 CYS B N   1 
ATOM   6297 C CA  . CYS C 1 220 ? -35.778 -0.115  -9.306  1   39.79  ? 390 CYS B CA  1 
ATOM   6298 C C   . CYS C 1 220 ? -35.19  0.18    -10.683 1   37.82  ? 390 CYS B C   1 
ATOM   6299 O O   . CYS C 1 220 ? -34.393 1.103   -10.86  1   36.83  ? 390 CYS B O   1 
ATOM   6300 C CB  . CYS C 1 220 ? -35.022 -1.279  -8.661  1   38.17  ? 390 CYS B CB  1 
ATOM   6301 S SG  . CYS C 1 220 ? -33.257 -0.974  -8.352  1   41.36  ? 390 CYS B SG  1 
ATOM   6302 N N   . LEU C 1 221 ? -35.596 -0.636  -11.654 1   38.04  ? 391 LEU B N   1 
ATOM   6303 C CA  . LEU C 1 221 ? -35.137 -0.504  -13.025 1   39.55  ? 391 LEU B CA  1 
ATOM   6304 C C   . LEU C 1 221 ? -35.45  0.902   -13.551 1   39.96  ? 391 LEU B C   1 
ATOM   6305 O O   . LEU C 1 221 ? -34.576 1.56    -14.11  1   38.25  ? 391 LEU B O   1 
ATOM   6306 C CB  . LEU C 1 221 ? -35.834 -1.612  -13.809 1   42.42  ? 391 LEU B CB  1 
ATOM   6307 C CG  . LEU C 1 221 ? -34.997 -2.378  -14.837 1   43.9   ? 391 LEU B CG  1 
ATOM   6308 C CD1 . LEU C 1 221 ? -33.602 -2.545  -14.33  1   42.95  ? 391 LEU B CD1 1 
ATOM   6309 C CD2 . LEU C 1 221 ? -35.585 -3.766  -15.008 1   47.75  ? 391 LEU B CD2 1 
ATOM   6310 N N   . LEU C 1 222 ? -36.683 1.379   -13.33  1   39.76  ? 392 LEU B N   1 
ATOM   6311 C CA  . LEU C 1 222 ? -37.066 2.732   -13.713 1   39.48  ? 392 LEU B CA  1 
ATOM   6312 C C   . LEU C 1 222 ? -36.112 3.753   -13.09  1   39.69  ? 392 LEU B C   1 
ATOM   6313 O O   . LEU C 1 222 ? -35.654 4.657   -13.781 1   43.63  ? 392 LEU B O   1 
ATOM   6314 C CB  . LEU C 1 222 ? -38.53  3.034   -13.375 1   38.54  ? 392 LEU B CB  1 
ATOM   6315 C CG  . LEU C 1 222 ? -39.626 2.217   -14.085 1   37.04  ? 392 LEU B CG  1 
ATOM   6316 C CD1 . LEU C 1 222 ? -40.995 2.8     -13.87  1   36.97  ? 392 LEU B CD1 1 
ATOM   6317 C CD2 . LEU C 1 222 ? -39.454 1.967   -15.563 1   36.79  ? 392 LEU B CD2 1 
ATOM   6318 N N   . ASP C 1 223 ? -35.806 3.613   -11.793 1   37.77  ? 393 ASP B N   1 
ATOM   6319 C CA  . ASP C 1 223 ? -34.942 4.569   -11.121 1   37.22  ? 393 ASP B CA  1 
ATOM   6320 C C   . ASP C 1 223 ? -33.538 4.52    -11.698 1   37.64  ? 393 ASP B C   1 
ATOM   6321 O O   . ASP C 1 223 ? -32.953 5.558   -11.986 1   39.38  ? 393 ASP B O   1 
ATOM   6322 C CB  . ASP C 1 223 ? -34.841 4.335   -9.63   1   36.03  ? 393 ASP B CB  1 
ATOM   6323 C CG  . ASP C 1 223 ? -36.089 4.722   -8.868  1   40.21  ? 393 ASP B CG  1 
ATOM   6324 O OD1 . ASP C 1 223 ? -36.614 5.819   -9.128  1   44.33  ? 393 ASP B OD1 1 
ATOM   6325 O OD2 . ASP C 1 223 ? -36.522 3.928   -8.021  1   42.62  ? 393 ASP B OD2 1 
ATOM   6326 N N   . LEU C 1 224 ? -32.994 3.31    -11.844 1   37.63  ? 394 LEU B N   1 
ATOM   6327 C CA  . LEU C 1 224 ? -31.608 3.144   -12.266 1   37.8   ? 394 LEU B CA  1 
ATOM   6328 C C   . LEU C 1 224 ? -31.412 3.693   -13.683 1   39.23  ? 394 LEU B C   1 
ATOM   6329 O O   . LEU C 1 224 ? -30.382 4.288   -13.993 1   40.44  ? 394 LEU B O   1 
ATOM   6330 C CB  . LEU C 1 224 ? -31.203 1.676   -12.112 1   35.43  ? 394 LEU B CB  1 
ATOM   6331 C CG  . LEU C 1 224 ? -29.701 1.381   -12.176 1   34.02  ? 394 LEU B CG  1 
ATOM   6332 C CD1 . LEU C 1 224 ? -28.91  2.162   -11.152 1   31.73  ? 394 LEU B CD1 1 
ATOM   6333 C CD2 . LEU C 1 224 ? -29.432 -0.11   -12.016 1   32.98  ? 394 LEU B CD2 1 
ATOM   6334 N N   . HIS C 1 225 ? -32.436 3.518   -14.526 1   38.53  ? 395 HIS B N   1 
ATOM   6335 C CA  . HIS C 1 225 ? -32.39  3.95    -15.905 1   37.8   ? 395 HIS B CA  1 
ATOM   6336 C C   . HIS C 1 225 ? -32.377 5.476   -15.936 1   43.66  ? 395 HIS B C   1 
ATOM   6337 O O   . HIS C 1 225 ? -31.758 6.047   -16.836 1   49.05  ? 395 HIS B O   1 
ATOM   6338 C CB  . HIS C 1 225 ? -33.544 3.316   -16.676 1   36.22  ? 395 HIS B CB  1 
ATOM   6339 C CG  . HIS C 1 225 ? -33.725 3.781   -18.078 1   37.27  ? 395 HIS B CG  1 
ATOM   6340 N ND1 . HIS C 1 225 ? -32.685 3.797   -18.968 1   37.58  ? 395 HIS B ND1 1 
ATOM   6341 C CD2 . HIS C 1 225 ? -34.793 4.213   -18.77  1   38.63  ? 395 HIS B CD2 1 
ATOM   6342 C CE1 . HIS C 1 225 ? -33.11  4.229   -20.149 1   38.65  ? 395 HIS B CE1 1 
ATOM   6343 N NE2 . HIS C 1 225 ? -34.387 4.495   -20.051 1   39.35  ? 395 HIS B NE2 1 
ATOM   6344 N N   . GLN C 1 226 ? -33.066 6.131   -14.981 1   45.53  ? 396 GLN B N   1 
ATOM   6345 C CA  . GLN C 1 226 ? -33.095 7.586   -14.918 1   46.82  ? 396 GLN B CA  1 
ATOM   6346 C C   . GLN C 1 226 ? -31.686 8.065   -14.615 1   45.5   ? 396 GLN B C   1 
ATOM   6347 O O   . GLN C 1 226 ? -31.166 8.937   -15.316 1   47.05  ? 396 GLN B O   1 
ATOM   6348 C CB  . GLN C 1 226 ? -34.086 8.167   -13.908 1   49.73  ? 396 GLN B CB  1 
ATOM   6349 C CG  . GLN C 1 226 ? -35.492 8.403   -14.45  1   59.83  ? 396 GLN B CG  1 
ATOM   6350 C CD  . GLN C 1 226 ? -35.531 9.074   -15.816 1   72.69  ? 396 GLN B CD  1 
ATOM   6351 O OE1 . GLN C 1 226 ? -36.171 8.59    -16.76  1   75.43  ? 396 GLN B OE1 1 
ATOM   6352 N NE2 . GLN C 1 226 ? -34.843 10.199  -15.965 1   75.46  ? 396 GLN B NE2 1 
ATOM   6353 N N   . THR C 1 227 ? -31.089 7.421   -13.604 1   41.55  ? 397 THR B N   1 
ATOM   6354 C CA  . THR C 1 227 ? -29.788 7.782   -13.075 1   40.42  ? 397 THR B CA  1 
ATOM   6355 C C   . THR C 1 227 ? -28.721 7.602   -14.16  1   42.06  ? 397 THR B C   1 
ATOM   6356 O O   . THR C 1 227 ? -27.739 8.353   -14.205 1   45.27  ? 397 THR B O   1 
ATOM   6357 C CB  . THR C 1 227 ? -29.514 6.982   -11.797 1   37.86  ? 397 THR B CB  1 
ATOM   6358 O OG1 . THR C 1 227 ? -30.364 7.514   -10.778 1   39.52  ? 397 THR B OG1 1 
ATOM   6359 C CG2 . THR C 1 227 ? -28.059 7.054   -11.364 1   34.18  ? 397 THR B CG2 1 
ATOM   6360 N N   . TYR C 1 228 ? -28.919 6.619   -15.053 1   39.54  ? 398 TYR B N   1 
ATOM   6361 C CA  . TYR C 1 228 ? -28.007 6.399   -16.162 1   38.74  ? 398 TYR B CA  1 
ATOM   6362 C C   . TYR C 1 228 ? -28.101 7.549   -17.174 1   44.33  ? 398 TYR B C   1 
ATOM   6363 O O   . TYR C 1 228 ? -27.07  7.983   -17.697 1   48.35  ? 398 TYR B O   1 
ATOM   6364 C CB  . TYR C 1 228 ? -28.354 5.059   -16.801 1   36.34  ? 398 TYR B CB  1 
ATOM   6365 C CG  . TYR C 1 228 ? -27.333 4.476   -17.765 1   37     ? 398 TYR B CG  1 
ATOM   6366 C CD1 . TYR C 1 228 ? -26.097 5.088   -17.99  1   36.62  ? 398 TYR B CD1 1 
ATOM   6367 C CD2 . TYR C 1 228 ? -27.602 3.27    -18.406 1   37.51  ? 398 TYR B CD2 1 
ATOM   6368 C CE1 . TYR C 1 228 ? -25.175 4.544   -18.87  1   38.03  ? 398 TYR B CE1 1 
ATOM   6369 C CE2 . TYR C 1 228 ? -26.691 2.719   -19.285 1   39.57  ? 398 TYR B CE2 1 
ATOM   6370 C CZ  . TYR C 1 228 ? -25.478 3.357   -19.516 1   40.91  ? 398 TYR B CZ  1 
ATOM   6371 O OH  . TYR C 1 228 ? -24.587 2.789   -20.387 1   44.78  ? 398 TYR B OH  1 
ATOM   6372 N N   . LEU C 1 229 ? -29.329 8.018   -17.482 1   42.53  ? 399 LEU B N   1 
ATOM   6373 C CA  . LEU C 1 229 ? -29.55  9.052   -18.481 1   42     ? 399 LEU B CA  1 
ATOM   6374 C C   . LEU C 1 229 ? -29.072 10.408  -17.967 1   43.4   ? 399 LEU B C   1 
ATOM   6375 O O   . LEU C 1 229 ? -28.552 11.21   -18.745 1   42.67  ? 399 LEU B O   1 
ATOM   6376 C CB  . LEU C 1 229 ? -31.033 9.114   -18.84  1   41.93  ? 399 LEU B CB  1 
ATOM   6377 C CG  . LEU C 1 229 ? -31.621 7.962   -19.659 1   41.02  ? 399 LEU B CG  1 
ATOM   6378 C CD1 . LEU C 1 229 ? -33.134 8.048   -19.593 1   42.35  ? 399 LEU B CD1 1 
ATOM   6379 C CD2 . LEU C 1 229 ? -31.177 7.971   -21.1   1   40.62  ? 399 LEU B CD2 1 
ATOM   6380 N N   . ARG C 1 230 ? -29.277 10.658  -16.663 1   43.99  ? 400 ARG B N   1 
ATOM   6381 C CA  . ARG C 1 230 ? -28.947 11.937  -16.049 1   45.94  ? 400 ARG B CA  1 
ATOM   6382 C C   . ARG C 1 230 ? -27.476 11.977  -15.633 1   43.17  ? 400 ARG B C   1 
ATOM   6383 O O   . ARG C 1 230 ? -26.974 13.02   -15.216 1   43.55  ? 400 ARG B O   1 
ATOM   6384 C CB  . ARG C 1 230 ? -29.858 12.228  -14.851 1   47.58  ? 400 ARG B CB  1 
ATOM   6385 C CG  . ARG C 1 230 ? -31.322 12.348  -15.24  1   54.75  ? 400 ARG B CG  1 
ATOM   6386 C CD  . ARG C 1 230 ? -32.198 12.774  -14.063 1   66.75  ? 400 ARG B CD  1 
ATOM   6387 N NE  . ARG C 1 230 ? -33.56  13.125  -14.497 1   77     ? 400 ARG B NE  1 
ATOM   6388 C CZ  . ARG C 1 230 ? -34.696 12.579  -14.061 1   81.84  ? 400 ARG B CZ  1 
ATOM   6389 N NH1 . ARG C 1 230 ? -34.682 11.644  -13.113 1   80.03  ? 400 ARG B NH1 1 
ATOM   6390 N NH2 . ARG C 1 230 ? -35.844 12.97   -14.593 1   81.38  ? 400 ARG B NH2 1 
ATOM   6391 N N   . ALA C 1 231 ? -26.797 10.837  -15.761 1   39.88  ? 401 ALA B N   1 
ATOM   6392 C CA  . ALA C 1 231 ? -25.492 10.646  -15.151 1   40.4   ? 401 ALA B CA  1 
ATOM   6393 C C   . ALA C 1 231 ? -24.466 11.69   -15.612 1   40.96  ? 401 ALA B C   1 
ATOM   6394 O O   . ALA C 1 231 ? -23.648 12.158  -14.823 1   42.66  ? 401 ALA B O   1 
ATOM   6395 C CB  . ALA C 1 231 ? -25.024 9.223   -15.37  1   40.08  ? 401 ALA B CB  1 
ATOM   6396 N N   . PRO C 1 232 ? -24.384 12.05   -16.907 1   41.1   ? 402 PRO B N   1 
ATOM   6397 C CA  . PRO C 1 232 ? -23.518 13.165  -17.306 1   42.57  ? 402 PRO B CA  1 
ATOM   6398 C C   . PRO C 1 232 ? -23.752 14.535  -16.654 1   45.73  ? 402 PRO B C   1 
ATOM   6399 O O   . PRO C 1 232 ? -22.868 15.394  -16.709 1   46.67  ? 402 PRO B O   1 
ATOM   6400 C CB  . PRO C 1 232 ? -23.717 13.189  -18.823 1   41.98  ? 402 PRO B CB  1 
ATOM   6401 C CG  . PRO C 1 232 ? -24.024 11.751  -19.16  1   40.74  ? 402 PRO B CG  1 
ATOM   6402 C CD  . PRO C 1 232 ? -24.96  11.318  -18.049 1   40.41  ? 402 PRO B CD  1 
ATOM   6403 N N   . GLN C 1 233 ? -24.93  14.732  -16.032 1   48.13  ? 403 GLN B N   1 
ATOM   6404 C CA  . GLN C 1 233 ? -25.309 16.003  -15.422 1   50.6   ? 403 GLN B CA  1 
ATOM   6405 C C   . GLN C 1 233 ? -25.333 15.951  -13.892 1   48.95  ? 403 GLN B C   1 
ATOM   6406 O O   . GLN C 1 233 ? -25.585 16.975  -13.256 1   51.06  ? 403 GLN B O   1 
ATOM   6407 C CB  . GLN C 1 233 ? -26.69  16.459  -15.885 1   54.14  ? 403 GLN B CB  1 
ATOM   6408 C CG  . GLN C 1 233 ? -26.624 17.45   -17.036 1   62.58  ? 403 GLN B CG  1 
ATOM   6409 C CD  . GLN C 1 233 ? -25.913 16.877  -18.241 1   68.95  ? 403 GLN B CD  1 
ATOM   6410 O OE1 . GLN C 1 233 ? -24.972 17.47   -18.787 1   72.59  ? 403 GLN B OE1 1 
ATOM   6411 N NE2 . GLN C 1 233 ? -26.386 15.715  -18.675 1   69.85  ? 403 GLN B NE2 1 
ATOM   6412 N N   . HIS C 1 234 ? -25.075 14.779  -13.296 1   43.82  ? 404 HIS B N   1 
ATOM   6413 C CA  . HIS C 1 234 ? -24.981 14.698  -11.847 1   41.03  ? 404 HIS B CA  1 
ATOM   6414 C C   . HIS C 1 234 ? -23.899 15.666  -11.346 1   40.38  ? 404 HIS B C   1 
ATOM   6415 O O   . HIS C 1 234 ? -22.928 15.942  -12.048 1   40.67  ? 404 HIS B O   1 
ATOM   6416 C CB  . HIS C 1 234 ? -24.722 13.242  -11.447 1   39.35  ? 404 HIS B CB  1 
ATOM   6417 C CG  . HIS C 1 234 ? -25.147 12.921  -10.061 1   38.73  ? 404 HIS B CG  1 
ATOM   6418 N ND1 . HIS C 1 234 ? -24.58  13.507  -8.953  1   39.05  ? 404 HIS B ND1 1 
ATOM   6419 C CD2 . HIS C 1 234 ? -26.088 12.096  -9.605  1   38.11  ? 404 HIS B CD2 1 
ATOM   6420 C CE1 . HIS C 1 234 ? -25.165 13.037  -7.865  1   38.98  ? 404 HIS B CE1 1 
ATOM   6421 N NE2 . HIS C 1 234 ? -26.076 12.172  -8.239  1   38.28  ? 404 HIS B NE2 1 
ATOM   6422 N N   . ALA C 1 235 ? -24.054 16.19   -10.127 1   39.27  ? 405 ALA B N   1 
ATOM   6423 C CA  . ALA C 1 235 ? -23.015 17.038  -9.556  1   39.89  ? 405 ALA B CA  1 
ATOM   6424 C C   . ALA C 1 235 ? -21.737 16.23   -9.307  1   39.4   ? 405 ALA B C   1 
ATOM   6425 O O   . ALA C 1 235 ? -20.626 16.759  -9.334  1   41.48  ? 405 ALA B O   1 
ATOM   6426 C CB  . ALA C 1 235 ? -23.51  17.686  -8.289  1   39.06  ? 405 ALA B CB  1 
ATOM   6427 N N   . GLN C 1 236 ? -21.908 14.93   -9.079  1   36.79  ? 406 GLN B N   1 
ATOM   6428 C CA  . GLN C 1 236 ? -20.809 14.046  -8.776  1   35.75  ? 406 GLN B CA  1 
ATOM   6429 C C   . GLN C 1 236 ? -20.426 13.269  -10.027 1   35.74  ? 406 GLN B C   1 
ATOM   6430 O O   . GLN C 1 236 ? -21.272 12.595  -10.618 1   36.19  ? 406 GLN B O   1 
ATOM   6431 C CB  . GLN C 1 236 ? -21.314 13.081  -7.707  1   35.52  ? 406 GLN B CB  1 
ATOM   6432 C CG  . GLN C 1 236 ? -21.186 13.617  -6.281  1   37.94  ? 406 GLN B CG  1 
ATOM   6433 C CD  . GLN C 1 236 ? -21.873 14.932  -5.987  1   38.09  ? 406 GLN B CD  1 
ATOM   6434 O OE1 . GLN C 1 236 ? -23.092 15.055  -6.149  1   37.86  ? 406 GLN B OE1 1 
ATOM   6435 N NE2 . GLN C 1 236 ? -21.103 15.873  -5.45   1   37.78  ? 406 GLN B NE2 1 
ATOM   6436 N N   . GLN C 1 237 ? -19.132 13.324  -10.376 1   34.78  ? 407 GLN B N   1 
ATOM   6437 C CA  . GLN C 1 237 ? -18.676 12.831  -11.659 1   34.02  ? 407 GLN B CA  1 
ATOM   6438 C C   . GLN C 1 237 ? -17.577 11.782  -11.541 1   34.15  ? 407 GLN B C   1 
ATOM   6439 O O   . GLN C 1 237 ? -17.183 11.236  -12.57  1   32.92  ? 407 GLN B O   1 
ATOM   6440 C CB  . GLN C 1 237 ? -18.244 14.06   -12.445 1   35.16  ? 407 GLN B CB  1 
ATOM   6441 C CG  . GLN C 1 237 ? -19.419 14.775  -13.103 1   35.56  ? 407 GLN B CG  1 
ATOM   6442 C CD  . GLN C 1 237 ? -20.12  13.898  -14.114 1   34.6   ? 407 GLN B CD  1 
ATOM   6443 O OE1 . GLN C 1 237 ? -19.471 13.21   -14.907 1   34.64  ? 407 GLN B OE1 1 
ATOM   6444 N NE2 . GLN C 1 237 ? -21.442 13.859  -14.058 1   33.66  ? 407 GLN B NE2 1 
ATOM   6445 N N   . SER C 1 238 ? -17.143 11.468  -10.301 1   35.71  ? 408 SER B N   1 
ATOM   6446 C CA  . SER C 1 238 ? -15.957 10.657  -10.035 1   35.41  ? 408 SER B CA  1 
ATOM   6447 C C   . SER C 1 238 ? -16.119 9.221   -10.516 1   34.22  ? 408 SER B C   1 
ATOM   6448 O O   . SER C 1 238 ? -15.134 8.579   -10.85  1   32.45  ? 408 SER B O   1 
ATOM   6449 C CB  . SER C 1 238 ? -15.584 10.683  -8.596  1   35.25  ? 408 SER B CB  1 
ATOM   6450 O OG  . SER C 1 238 ? -15.289 12.014  -8.198  1   39.05  ? 408 SER B OG  1 
ATOM   6451 N N   . ILE C 1 239 ? -17.36  8.734   -10.548 1   35.92  ? 409 ILE B N   1 
ATOM   6452 C CA  . ILE C 1 239 ? -17.627 7.366   -10.982 1   37.71  ? 409 ILE B CA  1 
ATOM   6453 C C   . ILE C 1 239 ? -17.538 7.253   -12.505 1   39.97  ? 409 ILE B C   1 
ATOM   6454 O O   . ILE C 1 239 ? -16.982 6.272   -12.997 1   44.59  ? 409 ILE B O   1 
ATOM   6455 C CB  . ILE C 1 239 ? -18.941 6.772   -10.426 1   34.19  ? 409 ILE B CB  1 
ATOM   6456 C CG1 . ILE C 1 239 ? -18.862 6.56    -8.918  1   32.36  ? 409 ILE B CG1 1 
ATOM   6457 C CG2 . ILE C 1 239 ? -19.255 5.466   -11.146 1   31.95  ? 409 ILE B CG2 1 
ATOM   6458 C CD1 . ILE C 1 239 ? -20.156 6.113   -8.282  1   30.91  ? 409 ILE B CD1 1 
ATOM   6459 N N   . ARG C 1 240 ? -18.076 8.231   -13.243 1   38.12  ? 410 ARG B N   1 
ATOM   6460 C CA  . ARG C 1 240 ? -17.996 8.176   -14.694 1   38.44  ? 410 ARG B CA  1 
ATOM   6461 C C   . ARG C 1 240 ? -16.547 8.284   -15.161 1   41.55  ? 410 ARG B C   1 
ATOM   6462 O O   . ARG C 1 240 ? -16.179 7.631   -16.144 1   41.67  ? 410 ARG B O   1 
ATOM   6463 C CB  . ARG C 1 240 ? -18.818 9.298   -15.327 1   38.18  ? 410 ARG B CB  1 
ATOM   6464 C CG  . ARG C 1 240 ? -20.323 9.133   -15.19  1   35.13  ? 410 ARG B CG  1 
ATOM   6465 C CD  . ARG C 1 240 ? -21.028 10.226  -15.93  1   34.97  ? 410 ARG B CD  1 
ATOM   6466 N NE  . ARG C 1 240 ? -20.706 10.121  -17.356 1   34.78  ? 410 ARG B NE  1 
ATOM   6467 C CZ  . ARG C 1 240 ? -20.331 11.112  -18.137 1   34.61  ? 410 ARG B CZ  1 
ATOM   6468 N NH1 . ARG C 1 240 ? -20.096 10.875  -19.398 1   35.78  ? 410 ARG B NH1 1 
ATOM   6469 N NH2 . ARG C 1 240 ? -20.206 12.324  -17.667 1   34.6   ? 410 ARG B NH2 1 
ATOM   6470 N N   . GLU C 1 241 ? -15.76  9.123   -14.454 1   43.15  ? 411 GLU B N   1 
ATOM   6471 C CA  . GLU C 1 241 ? -14.349 9.355   -14.737 1   43.39  ? 411 GLU B CA  1 
ATOM   6472 C C   . GLU C 1 241 ? -13.638 8.019   -14.594 1   43.07  ? 411 GLU B C   1 
ATOM   6473 O O   . GLU C 1 241 ? -12.971 7.568   -15.526 1   43.83  ? 411 GLU B O   1 
ATOM   6474 C CB  . GLU C 1 241 ? -13.658 10.3    -13.743 1   44.96  ? 411 GLU B CB  1 
ATOM   6475 C CG  . GLU C 1 241 ? -14.061 11.771  -13.8   1   48.18  ? 411 GLU B CG  1 
ATOM   6476 C CD  . GLU C 1 241 ? -13.9   12.481  -15.142 1   53.09  ? 411 GLU B CD  1 
ATOM   6477 O OE1 . GLU C 1 241 ? -12.868 12.301  -15.87  1   55.57  ? 411 GLU B OE1 1 
ATOM   6478 O OE2 . GLU C 1 241 ? -14.833 13.284  -15.428 1   53.91  ? 411 GLU B OE2 1 
ATOM   6479 N N   . LYS C 1 242 ? -13.826 7.413   -13.409 1   39.51  ? 412 LYS B N   1 
ATOM   6480 C CA  . LYS C 1 242 ? -13.257 6.133   -13.057 1   36.88  ? 412 LYS B CA  1 
ATOM   6481 C C   . LYS C 1 242 ? -13.518 5.118   -14.159 1   36.7   ? 412 LYS B C   1 
ATOM   6482 O O   . LYS C 1 242 ? -12.596 4.404   -14.548 1   39.07  ? 412 LYS B O   1 
ATOM   6483 C CB  . LYS C 1 242 ? -13.903 5.645   -11.762 1   37.13  ? 412 LYS B CB  1 
ATOM   6484 C CG  . LYS C 1 242 ? -13.5   4.239   -11.293 1   36.06  ? 412 LYS B CG  1 
ATOM   6485 C CD  . LYS C 1 242 ? -13.916 3.977   -9.848  1   33.75  ? 412 LYS B CD  1 
ATOM   6486 C CE  . LYS C 1 242 ? -13.706 2.601   -9.362  1   30.41  ? 412 LYS B CE  1 
ATOM   6487 N NZ  . LYS C 1 242 ? -14.787 2.259   -8.453  1   27.27  ? 412 LYS B NZ  1 
ATOM   6488 N N   . TYR C 1 243 ? -14.763 5.061   -14.645 1   34.79  ? 413 TYR B N   1 
ATOM   6489 C CA  . TYR C 1 243 ? -15.184 4.012   -15.555 1   36.2   ? 413 TYR B CA  1 
ATOM   6490 C C   . TYR C 1 243 ? -14.961 4.387   -17.019 1   39.11  ? 413 TYR B C   1 
ATOM   6491 O O   . TYR C 1 243 ? -15.491 3.694   -17.881 1   41.22  ? 413 TYR B O   1 
ATOM   6492 C CB  . TYR C 1 243 ? -16.632 3.6     -15.288 1   36.04  ? 413 TYR B CB  1 
ATOM   6493 C CG  . TYR C 1 243 ? -16.758 2.561   -14.189 1   35.46  ? 413 TYR B CG  1 
ATOM   6494 C CD1 . TYR C 1 243 ? -16.588 2.918   -12.863 1   36.03  ? 413 TYR B CD1 1 
ATOM   6495 C CD2 . TYR C 1 243 ? -16.99  1.226   -14.483 1   35     ? 413 TYR B CD2 1 
ATOM   6496 C CE1 . TYR C 1 243 ? -16.649 1.977   -11.851 1   35.54  ? 413 TYR B CE1 1 
ATOM   6497 C CE2 . TYR C 1 243 ? -17.059 0.275   -13.48  1   34.88  ? 413 TYR B CE2 1 
ATOM   6498 C CZ  . TYR C 1 243 ? -16.903 0.655   -12.157 1   34.34  ? 413 TYR B CZ  1 
ATOM   6499 O OH  . TYR C 1 243 ? -16.947 -0.239  -11.134 1   32.85  ? 413 TYR B OH  1 
ATOM   6500 N N   . LYS C 1 244 ? -14.182 5.446   -17.294 1   39.82  ? 414 LYS B N   1 
ATOM   6501 C CA  . LYS C 1 244 ? -13.628 5.71    -18.619 1   41.42  ? 414 LYS B CA  1 
ATOM   6502 C C   . LYS C 1 244 ? -12.384 4.859   -18.862 1   42.93  ? 414 LYS B C   1 
ATOM   6503 O O   . LYS C 1 244 ? -11.958 4.699   -20.007 1   47.13  ? 414 LYS B O   1 
ATOM   6504 C CB  . LYS C 1 244 ? -13.233 7.184   -18.784 1   41.24  ? 414 LYS B CB  1 
ATOM   6505 C CG  . LYS C 1 244 ? -14.395 8.028   -19.208 1   43.87  ? 414 LYS B CG  1 
ATOM   6506 C CD  . LYS C 1 244 ? -14.329 9.49    -18.799 1   48.82  ? 414 LYS B CD  1 
ATOM   6507 C CE  . LYS C 1 244 ? -15.74  10.05   -18.887 1   50.14  ? 414 LYS B CE  1 
ATOM   6508 N NZ  . LYS C 1 244 ? -15.816 11.432  -18.424 1   51.08  ? 414 LYS B NZ  1 
ATOM   6509 N N   . ASN C 1 245 ? -11.798 4.359   -17.77  1   41.02  ? 415 ASN B N   1 
ATOM   6510 C CA  . ASN C 1 245 ? -10.504 3.716   -17.783 1   42.28  ? 415 ASN B CA  1 
ATOM   6511 C C   . ASN C 1 245 ? -10.601 2.402   -18.546 1   41     ? 415 ASN B C   1 
ATOM   6512 O O   . ASN C 1 245 ? -11.53  1.614   -18.351 1   38.15  ? 415 ASN B O   1 
ATOM   6513 C CB  . ASN C 1 245 ? -10.018 3.506   -16.353 1   46.42  ? 415 ASN B CB  1 
ATOM   6514 C CG  . ASN C 1 245 ? -8.562  3.104   -16.281 1   54.2   ? 415 ASN B CG  1 
ATOM   6515 O OD1 . ASN C 1 245 ? -8.203  1.948   -16.538 1   55.89  ? 415 ASN B OD1 1 
ATOM   6516 N ND2 . ASN C 1 245 ? -7.699  4.054   -15.943 1   58.07  ? 415 ASN B ND2 1 
ATOM   6517 N N   . SER C 1 246 ? -9.575  2.146   -19.361 1   42.83  ? 416 SER B N   1 
ATOM   6518 C CA  . SER C 1 246 ? -9.511  0.926   -20.146 1   45.1   ? 416 SER B CA  1 
ATOM   6519 C C   . SER C 1 246 ? -9.697  -0.308  -19.26  1   44.27  ? 416 SER B C   1 
ATOM   6520 O O   . SER C 1 246 ? -10.127 -1.368  -19.737 1   42.74  ? 416 SER B O   1 
ATOM   6521 C CB  . SER C 1 246 ? -8.224  0.864   -20.907 1   48.54  ? 416 SER B CB  1 
ATOM   6522 O OG  . SER C 1 246 ? -7.176  0.496   -20.023 1   53.06  ? 416 SER B OG  1 
ATOM   6523 N N   . LYS C 1 247 ? -9.349  -0.151  -17.973 1   43.58  ? 417 LYS B N   1 
ATOM   6524 C CA  . LYS C 1 247 ? -9.447  -1.196  -16.966 1   41.35  ? 417 LYS B CA  1 
ATOM   6525 C C   . LYS C 1 247 ? -10.866 -1.737  -16.925 1   40.24  ? 417 LYS B C   1 
ATOM   6526 O O   . LYS C 1 247 ? -11.031 -2.941  -16.735 1   38.97  ? 417 LYS B O   1 
ATOM   6527 C CB  . LYS C 1 247 ? -9.146  -0.585  -15.599 1   40.46  ? 417 LYS B CB  1 
ATOM   6528 C CG  . LYS C 1 247 ? -9.23   -1.508  -14.402 1   39.57  ? 417 LYS B CG  1 
ATOM   6529 C CD  . LYS C 1 247 ? -8.663  -0.817  -13.171 1   43.43  ? 417 LYS B CD  1 
ATOM   6530 C CE  . LYS C 1 247 ? -8.082  -1.829  -12.225 1   46.19  ? 417 LYS B CE  1 
ATOM   6531 N NZ  . LYS C 1 247 ? -9.155  -2.754  -11.836 1   48.1   ? 417 LYS B NZ  1 
ATOM   6532 N N   . TYR C 1 248 ? -11.84  -0.826  -17.12  1   39.67  ? 418 TYR B N   1 
ATOM   6533 C CA  . TYR C 1 248 ? -13.262 -1.114  -17.034 1   38.96  ? 418 TYR B CA  1 
ATOM   6534 C C   . TYR C 1 248 ? -13.892 -0.936  -18.408 1   38.73  ? 418 TYR B C   1 
ATOM   6535 O O   . TYR C 1 248 ? -15.108 -0.771  -18.523 1   37.67  ? 418 TYR B O   1 
ATOM   6536 C CB  . TYR C 1 248 ? -13.993 -0.173  -16.074 1   40.31  ? 418 TYR B CB  1 
ATOM   6537 C CG  . TYR C 1 248 ? -13.413 -0.164  -14.675 1   40.76  ? 418 TYR B CG  1 
ATOM   6538 C CD1 . TYR C 1 248 ? -13.657 -1.215  -13.799 1   40.3   ? 418 TYR B CD1 1 
ATOM   6539 C CD2 . TYR C 1 248 ? -12.636 0.9     -14.239 1   41.1   ? 418 TYR B CD2 1 
ATOM   6540 C CE1 . TYR C 1 248 ? -13.139 -1.206  -12.514 1   40.99  ? 418 TYR B CE1 1 
ATOM   6541 C CE2 . TYR C 1 248 ? -12.092 0.905   -12.967 1   41.54  ? 418 TYR B CE2 1 
ATOM   6542 C CZ  . TYR C 1 248 ? -12.353 -0.143  -12.103 1   41.43  ? 418 TYR B CZ  1 
ATOM   6543 O OH  . TYR C 1 248 ? -11.814 -0.144  -10.852 1   43.79  ? 418 TYR B OH  1 
ATOM   6544 N N   . HIS C 1 249 ? -13.046 -0.942  -19.438 1   39.57  ? 419 HIS B N   1 
ATOM   6545 C CA  . HIS C 1 249 ? -13.548 -1.131  -20.785 1   41.85  ? 419 HIS B CA  1 
ATOM   6546 C C   . HIS C 1 249 ? -14.279 0.132   -21.226 1   42.4   ? 419 HIS B C   1 
ATOM   6547 O O   . HIS C 1 249 ? -15.176 0.055   -22.073 1   43.44  ? 419 HIS B O   1 
ATOM   6548 C CB  . HIS C 1 249 ? -14.406 -2.403  -20.857 1   40.61  ? 419 HIS B CB  1 
ATOM   6549 C CG  . HIS C 1 249 ? -13.682 -3.638  -20.43  1   43.71  ? 419 HIS B CG  1 
ATOM   6550 N ND1 . HIS C 1 249 ? -13.827 -4.181  -19.167 1   43.96  ? 419 HIS B ND1 1 
ATOM   6551 C CD2 . HIS C 1 249 ? -12.79  -4.426  -21.072 1   46.06  ? 419 HIS B CD2 1 
ATOM   6552 C CE1 . HIS C 1 249 ? -13.059 -5.268  -19.059 1   42.51  ? 419 HIS B CE1 1 
ATOM   6553 N NE2 . HIS C 1 249 ? -12.424 -5.435  -20.203 1   45.77  ? 419 HIS B NE2 1 
ATOM   6554 N N   . GLY C 1 250 ? -13.871 1.271   -20.638 1   40.18  ? 420 GLY B N   1 
ATOM   6555 C CA  . GLY C 1 250 ? -14.419 2.589   -20.922 1   40.35  ? 420 GLY B CA  1 
ATOM   6556 C C   . GLY C 1 250 ? -15.935 2.624   -21.095 1   40.48  ? 420 GLY B C   1 
ATOM   6557 O O   . GLY C 1 250 ? -16.404 3.343   -21.986 1   44.07  ? 420 GLY B O   1 
ATOM   6558 N N   . VAL C 1 251 ? -16.671 1.914   -20.213 1   36.39  ? 421 VAL B N   1 
ATOM   6559 C CA  . VAL C 1 251 ? -18.103 1.682   -20.356 1   34.16  ? 421 VAL B CA  1 
ATOM   6560 C C   . VAL C 1 251 ? -18.894 2.963   -20.134 1   35.23  ? 421 VAL B C   1 
ATOM   6561 O O   . VAL C 1 251 ? -19.973 3.099   -20.69  1   36.28  ? 421 VAL B O   1 
ATOM   6562 C CB  . VAL C 1 251 ? -18.641 0.552   -19.469 1   31.52  ? 421 VAL B CB  1 
ATOM   6563 C CG1 . VAL C 1 251 ? -18.165 -0.797  -19.966 1   32.15  ? 421 VAL B CG1 1 
ATOM   6564 C CG2 . VAL C 1 251 ? -18.276 0.728   -18.005 1   29.15  ? 421 VAL B CG2 1 
ATOM   6565 N N   . SER C 1 252 ? -18.383 3.873   -19.295 1   36.67  ? 422 SER B N   1 
ATOM   6566 C CA  . SER C 1 252 ? -19.09  5.11    -18.994 1   38.07  ? 422 SER B CA  1 
ATOM   6567 C C   . SER C 1 252 ? -19.111 6.008   -20.227 1   40.88  ? 422 SER B C   1 
ATOM   6568 O O   . SER C 1 252 ? -19.664 7.103   -20.185 1   43.33  ? 422 SER B O   1 
ATOM   6569 C CB  . SER C 1 252 ? -18.546 5.83    -17.77  1   36.7   ? 422 SER B CB  1 
ATOM   6570 O OG  . SER C 1 252 ? -17.181 6.19    -17.917 1   36.67  ? 422 SER B OG  1 
ATOM   6571 N N   . LEU C 1 253 ? -18.53  5.526   -21.329 1   41.27  ? 423 LEU B N   1 
ATOM   6572 C CA  . LEU C 1 253 ? -18.664 6.226   -22.601 1   45.22  ? 423 LEU B CA  1 
ATOM   6573 C C   . LEU C 1 253 ? -19.767 5.629   -23.48  1   44.73  ? 423 LEU B C   1 
ATOM   6574 O O   . LEU C 1 253 ? -19.935 6.068   -24.621 1   45.12  ? 423 LEU B O   1 
ATOM   6575 C CB  . LEU C 1 253 ? -17.324 6.186   -23.333 1   46.72  ? 423 LEU B CB  1 
ATOM   6576 C CG  . LEU C 1 253 ? -16.152 6.86    -22.617 1   46.76  ? 423 LEU B CG  1 
ATOM   6577 C CD1 . LEU C 1 253 ? -14.886 6.281   -23.254 1   46.84  ? 423 LEU B CD1 1 
ATOM   6578 C CD2 . LEU C 1 253 ? -16.225 8.407   -22.703 1   46.27  ? 423 LEU B CD2 1 
ATOM   6579 N N   . LEU C 1 254 ? -20.478 4.603   -22.982 1   41.31  ? 424 LEU B N   1 
ATOM   6580 C CA  . LEU C 1 254 ? -21.484 3.945   -23.796 1   39.06  ? 424 LEU B CA  1 
ATOM   6581 C C   . LEU C 1 254 ? -22.743 4.789   -23.694 1   41.38  ? 424 LEU B C   1 
ATOM   6582 O O   . LEU C 1 254 ? -22.923 5.549   -22.75  1   41.79  ? 424 LEU B O   1 
ATOM   6583 C CB  . LEU C 1 254 ? -21.726 2.505   -23.359 1   35.37  ? 424 LEU B CB  1 
ATOM   6584 C CG  . LEU C 1 254 ? -20.572 1.517   -23.561 1   34.22  ? 424 LEU B CG  1 
ATOM   6585 C CD1 . LEU C 1 254 ? -20.876 0.129   -23.019 1   32.03  ? 424 LEU B CD1 1 
ATOM   6586 C CD2 . LEU C 1 254 ? -20.193 1.405   -25.021 1   35.89  ? 424 LEU B CD2 1 
ATOM   6587 N N   . ASN C 1 255 ? -23.598 4.671   -24.699 1   45.04  ? 425 ASN B N   1 
ATOM   6588 C CA  . ASN C 1 255 ? -24.81  5.461   -24.726 1   47.16  ? 425 ASN B CA  1 
ATOM   6589 C C   . ASN C 1 255 ? -25.939 4.68    -24.074 1   46.24  ? 425 ASN B C   1 
ATOM   6590 O O   . ASN C 1 255 ? -26.3   3.582   -24.508 1   45.47  ? 425 ASN B O   1 
ATOM   6591 C CB  . ASN C 1 255 ? -25.155 5.887   -26.141 1   51.57  ? 425 ASN B CB  1 
ATOM   6592 C CG  . ASN C 1 255 ? -24.183 6.942   -26.58  1   56.17  ? 425 ASN B CG  1 
ATOM   6593 O OD1 . ASN C 1 255 ? -23.392 6.686   -27.488 1   57.99  ? 425 ASN B OD1 1 
ATOM   6594 N ND2 . ASN C 1 255 ? -24.185 8.087   -25.905 1   61.2   ? 425 ASN B ND2 1 
ATOM   6595 N N   . PRO C 1 256 ? -26.544 5.254   -23.02  1   44.78  ? 426 PRO B N   1 
ATOM   6596 C CA  . PRO C 1 256 ? -27.66  4.582   -22.368 1   44.1   ? 426 PRO B CA  1 
ATOM   6597 C C   . PRO C 1 256 ? -28.771 4.509   -23.423 1   46.3   ? 426 PRO B C   1 
ATOM   6598 O O   . PRO C 1 256 ? -28.814 5.323   -24.348 1   45.53  ? 426 PRO B O   1 
ATOM   6599 C CB  . PRO C 1 256 ? -27.949 5.486   -21.159 1   41.96  ? 426 PRO B CB  1 
ATOM   6600 C CG  . PRO C 1 256 ? -27.42  6.846   -21.568 1   42.97  ? 426 PRO B CG  1 
ATOM   6601 C CD  . PRO C 1 256 ? -26.23  6.583   -22.469 1   44.21  ? 426 PRO B CD  1 
ATOM   6602 N N   . PRO C 1 257 ? -29.661 3.488   -23.364 1   46.89  ? 427 PRO B N   1 
ATOM   6603 C CA  . PRO C 1 257 ? -30.733 3.374   -24.352 1   48.36  ? 427 PRO B CA  1 
ATOM   6604 C C   . PRO C 1 257 ? -31.809 4.382   -23.982 1   50.36  ? 427 PRO B C   1 
ATOM   6605 O O   . PRO C 1 257 ? -31.898 4.783   -22.817 1   49.11  ? 427 PRO B O   1 
ATOM   6606 C CB  . PRO C 1 257 ? -31.19  1.916   -24.188 1   48.37  ? 427 PRO B CB  1 
ATOM   6607 C CG  . PRO C 1 257 ? -30.846 1.551   -22.748 1   44.68  ? 427 PRO B CG  1 
ATOM   6608 C CD  . PRO C 1 257 ? -29.66  2.401   -22.363 1   43.48  ? 427 PRO B CD  1 
ATOM   6609 N N   . GLU C 1 258 ? -32.596 4.798   -24.985 1   55.31  ? 428 GLU B N   1 
ATOM   6610 C CA  . GLU C 1 258 ? -33.615 5.821   -24.778 1   58.43  ? 428 GLU B CA  1 
ATOM   6611 C C   . GLU C 1 258 ? -34.822 5.237   -24.04  1   59.7   ? 428 GLU B C   1 
ATOM   6612 O O   . GLU C 1 258 ? -35.406 5.908   -23.192 1   59.51  ? 428 GLU B O   1 
ATOM   6613 C CB  . GLU C 1 258 ? -34.099 6.415   -26.098 1   59.85  ? 428 GLU B CB  1 
ATOM   6614 C CG  . GLU C 1 258 ? -32.999 7.027   -26.955 1   64.97  ? 428 GLU B CG  1 
ATOM   6615 C CD  . GLU C 1 258 ? -33.579 7.483   -28.289 1   77.91  ? 428 GLU B CD  1 
ATOM   6616 O OE1 . GLU C 1 258 ? -34.845 7.468   -28.4   1   77.62  ? 428 GLU B OE1 1 
ATOM   6617 O OE2 . GLU C 1 258 ? -32.782 7.839   -29.213 1   83.17  ? 428 GLU B OE2 1 
ATOM   6618 N N   . THR C 1 259 ? -35.209 4.003   -24.413 1   59.14  ? 429 THR B N   1 
ATOM   6619 C CA  . THR C 1 259 ? -36.308 3.281   -23.78  1   58.03  ? 429 THR B CA  1 
ATOM   6620 C C   . THR C 1 259 ? -35.817 1.936   -23.258 1   56.14  ? 429 THR B C   1 
ATOM   6621 O O   . THR C 1 259 ? -34.785 1.431   -23.698 1   56.98  ? 429 THR B O   1 
ATOM   6622 C CB  . THR C 1 259 ? -37.483 3.045   -24.727 1   59.02  ? 429 THR B CB  1 
ATOM   6623 O OG1 . THR C 1 259 ? -36.847 2.656   -25.941 1   58.54  ? 429 THR B OG1 1 
ATOM   6624 C CG2 . THR C 1 259 ? -38.44  4.223   -24.809 1   58.96  ? 429 THR B CG2 1 
ATOM   6625 N N   . LEU C 1 260 ? -36.615 1.35    -22.361 1   54.31  ? 430 LEU B N   1 
ATOM   6626 C CA  . LEU C 1 260 ? -36.312 0.061   -21.772 1   56.01  ? 430 LEU B CA  1 
ATOM   6627 C C   . LEU C 1 260 ? -37.192 -1.034  -22.361 1   62.9   ? 430 LEU B C   1 
ATOM   6628 O O   . LEU C 1 260 ? -36.863 -2.211  -22.208 1   60.83  ? 430 LEU B O   1 
ATOM   6629 C CB  . LEU C 1 260 ? -36.494 0.132   -20.264 1   52.57  ? 430 LEU B CB  1 
ATOM   6630 C CG  . LEU C 1 260 ? -35.246 0.516   -19.482 1   51.56  ? 430 LEU B CG  1 
ATOM   6631 C CD1 . LEU C 1 260 ? -35.447 0.22    -17.99  1   51.24  ? 430 LEU B CD1 1 
ATOM   6632 C CD2 . LEU C 1 260 ? -34.035 -0.218  -20.055 1   53.25  ? 430 LEU B CD2 1 
ATOM   6633 N N   . ASN C 1 261 ? -38.323 -0.646  -22.974 1   71.92  ? 431 ASN B N   1 
ATOM   6634 C CA  . ASN C 1 261 ? -39.186 -1.632  -23.6   1   81.78  ? 431 ASN B CA  1 
ATOM   6635 C C   . ASN C 1 261 ? -39.42  -2.771  -22.601 1   80.54  ? 431 ASN B C   1 
ATOM   6636 O O   . ASN C 1 261 ? -39.253 -3.945  -22.932 1   82.32  ? 431 ASN B O   1 
ATOM   6637 C CB  . ASN C 1 261 ? -38.54  -2.094  -24.907 1   98.33  ? 431 ASN B CB  1 
ATOM   6638 C CG  . ASN C 1 261 ? -39.079 -3.408  -25.438 1   114.05 ? 431 ASN B CG  1 
ATOM   6639 O OD1 . ASN C 1 261 ? -38.535 -4.481  -25.129 1   103.62 ? 431 ASN B OD1 1 
ATOM   6640 N ND2 . ASN C 1 261 ? -40.139 -3.345  -26.237 1   123.83 ? 431 ASN B ND2 1 
ATOM   6641 N N   . VAL C 1 262 ? -39.705 -2.411  -21.356 1   76.96  ? 432 VAL B N   1 
ATOM   6642 C CA  . VAL C 1 262 ? -40.011 -3.465  -20.349 1   74.15  ? 432 VAL B CA  1 
ATOM   6643 C C   . VAL C 1 262 ? -41.484 -3.825  -20.571 1   81     ? 432 VAL B C   1 
ATOM   6644 O O   . VAL C 1 262 ? -42.323 -2.915  -20.458 1   88.37  ? 432 VAL B O   1 
ATOM   6645 C CB  . VAL C 1 262 ? -39.689 -3.015  -18.911 1   65.02  ? 432 VAL B CB  1 
ATOM   6646 C CG1 . VAL C 1 262 ? -39.838 -4.164  -17.925 1   54.5   ? 432 VAL B CG1 1 
ATOM   6647 C CG2 . VAL C 1 262 ? -38.287 -2.439  -18.799 1   64.02  ? 432 VAL B CG2 1 
ATOM   6648 N N   . HIS C 1 263 ? -41.779 -5.081  -20.913 1   82.66  ? 433 HIS B N   1 
ATOM   6649 C CA  . HIS C 1 263 ? -43.166 -5.469  -21.281 1   78.35  ? 433 HIS B CA  1 
ATOM   6650 C C   . HIS C 1 263 ? -43.758 -6.472  -20.298 1   76.66  ? 433 HIS B C   1 
ATOM   6651 O O   . HIS C 1 263 ? -43.15  -6.753  -19.25  1   75.24  ? 433 HIS B O   1 
ATOM   6652 C CB  . HIS C 1 263 ? -43.175 -6.186  -22.629 1   83.42  ? 433 HIS B CB  1 
ATOM   6653 C CG  . HIS C 1 263 ? -43.225 -5.318  -23.838 1   96.18  ? 433 HIS B CG  1 
ATOM   6654 N ND1 . HIS C 1 263 ? -43.366 -5.856  -25.098 1   104.57 ? 433 HIS B ND1 1 
ATOM   6655 C CD2 . HIS C 1 263 ? -43.156 -3.994  -24.004 1   99.39  ? 433 HIS B CD2 1 
ATOM   6656 C CE1 . HIS C 1 263 ? -43.384 -4.878  -25.989 1   103.99 ? 433 HIS B CE1 1 
ATOM   6657 N NE2 . HIS C 1 263 ? -43.258 -3.738  -25.347 1   109.63 ? 433 HIS B NE2 1 
ATOM   6658 N N   . HIS C 1 264 ? -44.923 -7.012  -20.651 1   78.62  ? 434 HIS B N   1 
ATOM   6659 C CA  . HIS C 1 264 ? -45.585 -8.022  -19.789 1   78.37  ? 434 HIS B CA  1 
ATOM   6660 C C   . HIS C 1 264 ? -45.62  -9.378  -20.486 1   77.53  ? 434 HIS B C   1 
ATOM   6661 O O   . HIS C 1 264 ? -46.143 -9.481  -21.608 1   78.27  ? 434 HIS B O   1 
ATOM   6662 C CB  . HIS C 1 264 ? -47.014 -7.623  -19.416 1   83.1   ? 434 HIS B CB  1 
ATOM   6663 C CG  . HIS C 1 264 ? -47.727 -8.692  -18.657 1   85.46  ? 434 HIS B CG  1 
ATOM   6664 N ND1 . HIS C 1 264 ? -47.415 -9.002  -17.351 1   83.18  ? 434 HIS B ND1 1 
ATOM   6665 C CD2 . HIS C 1 264 ? -48.707 -9.531  -19.009 1   83.47  ? 434 HIS B CD2 1 
ATOM   6666 C CE1 . HIS C 1 264 ? -48.193 -9.989  -16.939 1   80.63  ? 434 HIS B CE1 1 
ATOM   6667 N NE2 . HIS C 1 264 ? -48.983 -10.328 -17.931 1   82.54  ? 434 HIS B NE2 1 
ATOM   6668 N N   . HIS C 1 265 ? -45.065 -10.385 -19.828 1   71.99  ? 435 HIS B N   1 
ATOM   6669 C CA  . HIS C 1 265 ? -45.075 -11.756 -20.327 1   72.82  ? 435 HIS B CA  1 
ATOM   6670 C C   . HIS C 1 265 ? -46.426 -12.411 -20.007 1   77.55  ? 435 HIS B C   1 
ATOM   6671 O O   . HIS C 1 265 ? -46.746 -12.628 -18.843 1   79.88  ? 435 HIS B O   1 
ATOM   6672 C CB  . HIS C 1 265 ? -43.906 -12.555 -19.723 1   70.51  ? 435 HIS B CB  1 
ATOM   6673 C CG  . HIS C 1 265 ? -42.508 -12.123 -20.069 1   70.09  ? 435 HIS B CG  1 
ATOM   6674 N ND1 . HIS C 1 265 ? -41.44  -12.987 -19.942 1   67.05  ? 435 HIS B ND1 1 
ATOM   6675 C CD2 . HIS C 1 265 ? -41.982 -10.962 -20.511 1   71.73  ? 435 HIS B CD2 1 
ATOM   6676 C CE1 . HIS C 1 265 ? -40.323 -12.372 -20.301 1   69.41  ? 435 HIS B CE1 1 
ATOM   6677 N NE2 . HIS C 1 265 ? -40.626 -11.138 -20.647 1   71.95  ? 435 HIS B NE2 1 
ATOM   6678 N N   . HIS C 1 266 ? -47.2   -12.778 -21.041 1   79.8   ? 436 HIS B N   1 
ATOM   6679 C CA  . HIS C 1 266 ? -48.597 -13.156 -20.871 1   77.72  ? 436 HIS B CA  1 
ATOM   6680 C C   . HIS C 1 266 ? -48.694 -14.656 -20.607 1   78.57  ? 436 HIS B C   1 
ATOM   6681 O O   . HIS C 1 266 ? -48.479 -15.476 -21.507 1   83.66  ? 436 HIS B O   1 
ATOM   6682 C CB  . HIS C 1 266 ? -49.441 -12.74  -22.084 1   78.87  ? 436 HIS B CB  1 
ATOM   6683 C CG  . HIS C 1 266 ? -49.795 -11.292 -22.191 1   79.6   ? 436 HIS B CG  1 
ATOM   6684 N ND1 . HIS C 1 266 ? -48.86  -10.288 -22.366 1   80.24  ? 436 HIS B ND1 1 
ATOM   6685 C CD2 . HIS C 1 266 ? -50.996 -10.689 -22.165 1   80.24  ? 436 HIS B CD2 1 
ATOM   6686 C CE1 . HIS C 1 266 ? -49.481 -9.116  -22.44  1   81.09  ? 436 HIS B CE1 1 
ATOM   6687 N NE2 . HIS C 1 266 ? -50.784 -9.343  -22.335 1   82.14  ? 436 HIS B NE2 1 
ATOM   6688 N N   . HIS C 1 267 ? -49.052 -14.985 -19.358 1   74.5   ? 437 HIS B N   1 
ATOM   6689 C CA  . HIS C 1 267 ? -49.369 -16.335 -18.909 1   69.03  ? 437 HIS B CA  1 
ATOM   6690 C C   . HIS C 1 267 ? -48.093 -17.172 -18.902 1   64.16  ? 437 HIS B C   1 
ATOM   6691 O O   . HIS C 1 267 ? -48.082 -18.256 -19.463 1   62.91  ? 437 HIS B O   1 
ATOM   6692 C CB  . HIS C 1 267 ? -50.421 -17.007 -19.799 1   73.99  ? 437 HIS B CB  1 
ATOM   6693 C CG  . HIS C 1 267 ? -51.629 -16.208 -20.215 1   81.08  ? 437 HIS B CG  1 
ATOM   6694 N ND1 . HIS C 1 267 ? -52.635 -15.795 -19.365 1   83.48  ? 437 HIS B ND1 1 
ATOM   6695 C CD2 . HIS C 1 267 ? -52     -15.79  -21.441 1   85.31  ? 437 HIS B CD2 1 
ATOM   6696 C CE1 . HIS C 1 267 ? -53.557 -15.132 -20.056 1   87.97  ? 437 HIS B CE1 1 
ATOM   6697 N NE2 . HIS C 1 267 ? -53.191 -15.113 -21.322 1   89.12  ? 437 HIS B NE2 1 
ATOM   6698 N N   . HIS C 1 268 ? -47.029 -16.643 -18.277 1   62.7   ? 438 HIS B N   1 
ATOM   6699 C CA  . HIS C 1 268 ? -45.722 -17.283 -18.193 1   63.48  ? 438 HIS B CA  1 
ATOM   6700 C C   . HIS C 1 268 ? -45.636 -18.123 -16.903 1   58.15  ? 438 HIS B C   1 
ATOM   6701 O O   . HIS C 1 268 ? -45.281 -17.629 -15.82  1   51.42  ? 438 HIS B O   1 
ATOM   6702 C CB  . HIS C 1 268 ? -44.585 -16.269 -18.441 1   65.38  ? 438 HIS B CB  1 
ATOM   6703 C CG  . HIS C 1 268 ? -43.218 -16.822 -18.8   1   70.62  ? 438 HIS B CG  1 
ATOM   6704 N ND1 . HIS C 1 268 ? -42.185 -15.985 -19.181 1   72.09  ? 438 HIS B ND1 1 
ATOM   6705 C CD2 . HIS C 1 268 ? -42.68  -18.068 -18.813 1   73.92  ? 438 HIS B CD2 1 
ATOM   6706 C CE1 . HIS C 1 268 ? -41.083 -16.697 -19.411 1   72.66  ? 438 HIS B CE1 1 
ATOM   6707 N NE2 . HIS C 1 268 ? -41.366 -17.966 -19.193 1   74.51  ? 438 HIS B NE2 1 
ATOM   6708 N N   . SER D 2 4   ? -14.713 5.111   27.834  1   61.95  ? 0   SER C N   1 
ATOM   6709 C CA  . SER D 2 4   ? -16.117 4.738   28.157  1   63.21  ? 0   SER C CA  1 
ATOM   6710 C C   . SER D 2 4   ? -17.035 5.957   27.963  1   63.1   ? 0   SER C C   1 
ATOM   6711 O O   . SER D 2 4   ? -17.935 5.964   27.106  1   60.72  ? 0   SER C O   1 
ATOM   6712 C CB  . SER D 2 4   ? -16.175 4.147   29.551  1   62.22  ? 0   SER C CB  1 
ATOM   6713 O OG  . SER D 2 4   ? -17.414 3.489   29.778  1   62.74  ? 0   SER C OG  1 
ATOM   6714 N N   . MET D 2 5   ? -16.745 7.019   28.729  1   59.81  ? 1   MET C N   1 
ATOM   6715 C CA  . MET D 2 5   ? -17.345 8.326   28.529  1   55.14  ? 1   MET C CA  1 
ATOM   6716 C C   . MET D 2 5   ? -16.255 9.309   28.099  1   57.83  ? 1   MET C C   1 
ATOM   6717 O O   . MET D 2 5   ? -16.324 10.505  28.401  1   57.22  ? 1   MET C O   1 
ATOM   6718 C CB  . MET D 2 5   ? -17.963 8.785   29.846  1   51.98  ? 1   MET C CB  1 
ATOM   6719 C CG  . MET D 2 5   ? -18.954 7.803   30.383  1   51.15  ? 1   MET C CG  1 
ATOM   6720 S SD  . MET D 2 5   ? -20.529 8.054   29.549  1   53.76  ? 1   MET C SD  1 
ATOM   6721 C CE  . MET D 2 5   ? -20.936 9.769   29.924  1   51.96  ? 1   MET C CE  1 
ATOM   6722 N N   . GLU D 2 6   ? -15.241 8.769   27.399  1   59.88  ? 2   GLU C N   1 
ATOM   6723 C CA  . GLU D 2 6   ? -14.071 9.511   26.968  1   62.32  ? 2   GLU C CA  1 
ATOM   6724 C C   . GLU D 2 6   ? -14.426 10.332  25.737  1   60.37  ? 2   GLU C C   1 
ATOM   6725 O O   . GLU D 2 6   ? -13.713 11.276  25.425  1   64.28  ? 2   GLU C O   1 
ATOM   6726 C CB  . GLU D 2 6   ? -12.895 8.591   26.637  1   69.16  ? 2   GLU C CB  1 
ATOM   6727 C CG  . GLU D 2 6   ? -11.514 9.16    26.969  1   81.91  ? 2   GLU C CG  1 
ATOM   6728 C CD  . GLU D 2 6   ? -10.894 10.311  26.172  1   90.86  ? 2   GLU C CD  1 
ATOM   6729 O OE1 . GLU D 2 6   ? -10.66  10.133  24.955  1   98.53  ? 2   GLU C OE1 1 
ATOM   6730 O OE2 . GLU D 2 6   ? -10.598 11.382  26.757  1   88.37  ? 2   GLU C OE2 1 
ATOM   6731 N N   . ASN D 2 7   ? -15.507 9.949   25.037  1   55.51  ? 3   ASN C N   1 
ATOM   6732 C CA  . ASN D 2 7   ? -15.949 10.638  23.836  1   51.71  ? 3   ASN C CA  1 
ATOM   6733 C C   . ASN D 2 7   ? -16.991 11.695  24.171  1   48.33  ? 3   ASN C C   1 
ATOM   6734 O O   . ASN D 2 7   ? -17.28  12.531  23.333  1   48.04  ? 3   ASN C O   1 
ATOM   6735 C CB  . ASN D 2 7   ? -16.497 9.672   22.796  1   51.8   ? 3   ASN C CB  1 
ATOM   6736 C CG  . ASN D 2 7   ? -15.417 8.85    22.132  1   56.51  ? 3   ASN C CG  1 
ATOM   6737 O OD1 . ASN D 2 7   ? -14.223 9.202   22.149  1   59.24  ? 3   ASN C OD1 1 
ATOM   6738 N ND2 . ASN D 2 7   ? -15.826 7.75    21.52   1   57.48  ? 3   ASN C ND2 1 
ATOM   6739 N N   . PHE D 2 8   ? -17.593 11.615  25.362  1   47.34  ? 4   PHE C N   1 
ATOM   6740 C CA  . PHE D 2 8   ? -18.526 12.632  25.829  1   45.87  ? 4   PHE C CA  1 
ATOM   6741 C C   . PHE D 2 8   ? -17.748 13.7    26.584  1   49.01  ? 4   PHE C C   1 
ATOM   6742 O O   . PHE D 2 8   ? -16.929 13.379  27.445  1   52.18  ? 4   PHE C O   1 
ATOM   6743 C CB  . PHE D 2 8   ? -19.677 12.031  26.637  1   42.19  ? 4   PHE C CB  1 
ATOM   6744 C CG  . PHE D 2 8   ? -20.543 11.152  25.752  1   41     ? 4   PHE C CG  1 
ATOM   6745 C CD1 . PHE D 2 8   ? -21.283 11.712  24.715  1   40     ? 4   PHE C CD1 1 
ATOM   6746 C CD2 . PHE D 2 8   ? -20.558 9.769   25.909  1   40.78  ? 4   PHE C CD2 1 
ATOM   6747 C CE1 . PHE D 2 8   ? -22.043 10.921  23.874  1   38.91  ? 4   PHE C CE1 1 
ATOM   6748 C CE2 . PHE D 2 8   ? -21.312 8.978   25.056  1   39.25  ? 4   PHE C CE2 1 
ATOM   6749 C CZ  . PHE D 2 8   ? -22.049 9.556   24.049  1   38.9   ? 4   PHE C CZ  1 
ATOM   6750 N N   . GLN D 2 9   ? -18.005 14.962  26.224  1   49.97  ? 5   GLN C N   1 
ATOM   6751 C CA  . GLN D 2 9   ? -17.386 16.078  26.911  1   53.64  ? 5   GLN C CA  1 
ATOM   6752 C C   . GLN D 2 9   ? -18.472 16.952  27.511  1   51.79  ? 5   GLN C C   1 
ATOM   6753 O O   . GLN D 2 9   ? -19.418 17.339  26.826  1   49.85  ? 5   GLN C O   1 
ATOM   6754 C CB  . GLN D 2 9   ? -16.467 16.808  25.949  1   60.56  ? 5   GLN C CB  1 
ATOM   6755 C CG  . GLN D 2 9   ? -15.269 17.436  26.642  1   70.12  ? 5   GLN C CG  1 
ATOM   6756 C CD  . GLN D 2 9   ? -15.468 18.921  26.745  1   75.59  ? 5   GLN C CD  1 
ATOM   6757 O OE1 . GLN D 2 9   ? -16.265 19.489  25.991  1   75.86  ? 5   GLN C OE1 1 
ATOM   6758 N NE2 . GLN D 2 9   ? -14.717 19.553  27.636  1   79.3   ? 5   GLN C NE2 1 
ATOM   6759 N N   . LYS D 2 10  ? -18.337 17.191  28.82   1   52.62  ? 6   LYS C N   1 
ATOM   6760 C CA  . LYS D 2 10  ? -19.391 17.784  29.631  1   50.65  ? 6   LYS C CA  1 
ATOM   6761 C C   . LYS D 2 10  ? -19.402 19.285  29.376  1   48.4   ? 6   LYS C C   1 
ATOM   6762 O O   . LYS D 2 10  ? -18.354 19.854  29.144  1   49.38  ? 6   LYS C O   1 
ATOM   6763 C CB  . LYS D 2 10  ? -19.116 17.363  31.077  1   54.18  ? 6   LYS C CB  1 
ATOM   6764 C CG  . LYS D 2 10  ? -20.072 17.869  32.15   1   57.77  ? 6   LYS C CG  1 
ATOM   6765 C CD  . LYS D 2 10  ? -19.7   17.455  33.586  1   59.98  ? 6   LYS C CD  1 
ATOM   6766 C CE  . LYS D 2 10  ? -18.586 18.278  34.219  1   61.85  ? 6   LYS C CE  1 
ATOM   6767 N NZ  . LYS D 2 10  ? -17.859 17.63   35.312  1   63.57  ? 6   LYS C NZ  1 
ATOM   6768 N N   . VAL D 2 11  ? -20.588 19.893  29.367  1   47.18  ? 7   VAL C N   1 
ATOM   6769 C CA  . VAL D 2 11  ? -20.752 21.288  28.979  1   49.48  ? 7   VAL C CA  1 
ATOM   6770 C C   . VAL D 2 11  ? -21.274 22.069  30.186  1   51.85  ? 7   VAL C C   1 
ATOM   6771 O O   . VAL D 2 11  ? -20.649 23.031  30.628  1   54.4   ? 7   VAL C O   1 
ATOM   6772 C CB  . VAL D 2 11  ? -21.671 21.479  27.75   1   47.11  ? 7   VAL C CB  1 
ATOM   6773 C CG1 . VAL D 2 11  ? -21.963 22.95   27.493  1   46.91  ? 7   VAL C CG1 1 
ATOM   6774 C CG2 . VAL D 2 11  ? -21.143 20.781  26.492  1   45.65  ? 7   VAL C CG2 1 
ATOM   6775 N N   . GLU D 2 12  ? -22.415 21.619  30.722  1   51.69  ? 8   GLU C N   1 
ATOM   6776 C CA  . GLU D 2 12  ? -22.987 22.189  31.928  1   56.33  ? 8   GLU C CA  1 
ATOM   6777 C C   . GLU D 2 12  ? -24.008 21.224  32.541  1   57.54  ? 8   GLU C C   1 
ATOM   6778 O O   . GLU D 2 12  ? -24.42  20.257  31.897  1   58.59  ? 8   GLU C O   1 
ATOM   6779 C CB  . GLU D 2 12  ? -23.611 23.527  31.537  1   60.15  ? 8   GLU C CB  1 
ATOM   6780 C CG  . GLU D 2 12  ? -24.969 23.354  30.868  1   60.44  ? 8   GLU C CG  1 
ATOM   6781 C CD  . GLU D 2 12  ? -25.472 24.555  30.117  1   61.68  ? 8   GLU C CD  1 
ATOM   6782 O OE1 . GLU D 2 12  ? -24.635 25.433  29.846  1   66.24  ? 8   GLU C OE1 1 
ATOM   6783 O OE2 . GLU D 2 12  ? -26.681 24.594  29.812  1   60.14  ? 8   GLU C OE2 1 
ATOM   6784 N N   . LYS D 2 13  ? -24.417 21.504  33.794  1   58.96  ? 9   LYS C N   1 
ATOM   6785 C CA  . LYS D 2 13  ? -25.476 20.764  34.469  1   56.42  ? 9   LYS C CA  1 
ATOM   6786 C C   . LYS D 2 13  ? -26.815 21.307  33.991  1   52.73  ? 9   LYS C C   1 
ATOM   6787 O O   . LYS D 2 13  ? -26.919 22.499  33.735  1   54.23  ? 9   LYS C O   1 
ATOM   6788 C CB  . LYS D 2 13  ? -25.426 21.077  35.967  1   59.31  ? 9   LYS C CB  1 
ATOM   6789 C CG  . LYS D 2 13  ? -26.159 20.096  36.885  1   62.39  ? 9   LYS C CG  1 
ATOM   6790 C CD  . LYS D 2 13  ? -26.594 20.768  38.183  1   72.58  ? 9   LYS C CD  1 
ATOM   6791 C CE  . LYS D 2 13  ? -27.661 20.019  38.93   1   85.11  ? 9   LYS C CE  1 
ATOM   6792 N NZ  . LYS D 2 13  ? -28.525 20.941  39.685  1   87.06  ? 9   LYS C NZ  1 
ATOM   6793 N N   . ILE D 2 14  ? -27.836 20.452  33.853  1   51.99  ? 10  ILE C N   1 
ATOM   6794 C CA  . ILE D 2 14  ? -29.161 20.973  33.526  1   53.14  ? 10  ILE C CA  1 
ATOM   6795 C C   . ILE D 2 14  ? -30.257 20.465  34.47   1   57.62  ? 10  ILE C C   1 
ATOM   6796 O O   . ILE D 2 14  ? -31.428 20.546  34.128  1   64.61  ? 10  ILE C O   1 
ATOM   6797 C CB  . ILE D 2 14  ? -29.511 20.802  32.035  1   47.84  ? 10  ILE C CB  1 
ATOM   6798 C CG1 . ILE D 2 14  ? -29.667 19.377  31.623  1   41.93  ? 10  ILE C CG1 1 
ATOM   6799 C CG2 . ILE D 2 14  ? -28.472 21.5    31.165  1   55.68  ? 10  ILE C CG2 1 
ATOM   6800 C CD1 . ILE D 2 14  ? -29.46  19.137  30.14   1   39.2   ? 10  ILE C CD1 1 
ATOM   6801 N N   . GLY D 2 15  ? -29.898 19.988  35.667  1   58.9   ? 11  GLY C N   1 
ATOM   6802 C CA  . GLY D 2 15  ? -30.886 19.775  36.715  1   62.28  ? 11  GLY C CA  1 
ATOM   6803 C C   . GLY D 2 15  ? -30.9   18.339  37.231  1   65.92  ? 11  GLY C C   1 
ATOM   6804 O O   . GLY D 2 15  ? -29.954 17.594  37.012  1   68.15  ? 11  GLY C O   1 
ATOM   6805 N N   . GLU D 2 16  ? -31.896 18.021  38.056  1   70.76  ? 12  GLU C N   1 
ATOM   6806 C CA  . GLU D 2 16  ? -32.066 16.662  38.626  1   71.48  ? 12  GLU C CA  1 
ATOM   6807 C C   . GLU D 2 16  ? -33.568 16.373  38.624  1   79.25  ? 12  GLU C C   1 
ATOM   6808 O O   . GLU D 2 16  ? -34.342 17.319  38.832  1   81.41  ? 12  GLU C O   1 
ATOM   6809 C CB  . GLU D 2 16  ? -31.53  16.579  40.049  1   66.8   ? 12  GLU C CB  1 
ATOM   6810 C CG  . GLU D 2 16  ? -30.017 16.735  40.156  1   73.83  ? 12  GLU C CG  1 
ATOM   6811 C CD  . GLU D 2 16  ? -29.55  16.717  41.595  1   79.69  ? 12  GLU C CD  1 
ATOM   6812 O OE1 . GLU D 2 16  ? -30.418 16.776  42.486  1   80.91  ? 12  GLU C OE1 1 
ATOM   6813 O OE2 . GLU D 2 16  ? -28.33  16.645  41.828  1   78.65  ? 12  GLU C OE2 1 
ATOM   6814 N N   . GLY D 2 17  ? -33.974 15.129  38.405  1   93.62  ? 13  GLY C N   1 
ATOM   6815 C CA  . GLY D 2 17  ? -35.413 14.83   38.261  1   95.73  ? 13  GLY C CA  1 
ATOM   6816 C C   . GLY D 2 17  ? -35.894 13.795  39.245  1   92.21  ? 13  GLY C C   1 
ATOM   6817 O O   . GLY D 2 17  ? -35.689 14.008  40.455  1   94.8   ? 13  GLY C O   1 
ATOM   6818 N N   . THR D 2 18  ? -36.542 12.734  38.765  1   89.16  ? 14  THR C N   1 
ATOM   6819 C CA  . THR D 2 18  ? -36.952 11.663  39.69   1   86.24  ? 14  THR C CA  1 
ATOM   6820 C C   . THR D 2 18  ? -35.685 11.157  40.346  1   96.14  ? 14  THR C C   1 
ATOM   6821 O O   . THR D 2 18  ? -35.687 10.957  41.584  1   90.2   ? 14  THR C O   1 
ATOM   6822 C CB  . THR D 2 18  ? -37.755 10.554  39.009  1   72.9   ? 14  THR C CB  1 
ATOM   6823 O OG1 . THR D 2 18  ? -38.949 11.172  38.543  1   62.94  ? 14  THR C OG1 1 
ATOM   6824 C CG2 . THR D 2 18  ? -38.11  9.415   39.947  1   65.85  ? 14  THR C CG2 1 
ATOM   6825 N N   . TYR D 2 19  ? -34.615 11.03   39.558  1   94.88  ? 15  TYR C N   1 
ATOM   6826 C CA  . TYR D 2 19  ? -33.348 10.487  40.103  1   89.9   ? 15  TYR C CA  1 
ATOM   6827 C C   . TYR D 2 19  ? -32.199 10.887  39.217  1   89.66  ? 15  TYR C C   1 
ATOM   6828 O O   . TYR D 2 19  ? -32.382 11.059  38.006  1   89.39  ? 15  TYR C O   1 
ATOM   6829 C CB  . TYR D 2 19  ? -33.485 8.965   40.178  1   82.21  ? 15  TYR C CB  1 
ATOM   6830 C CG  . TYR D 2 19  ? -33.645 8.277   38.83   1   73.82  ? 15  TYR C CG  1 
ATOM   6831 C CD1 . TYR D 2 19  ? -34.871 8.227   38.18   1   72.74  ? 15  TYR C CD1 1 
ATOM   6832 C CD2 . TYR D 2 19  ? -32.559 7.683   38.21   1   66.43  ? 15  TYR C CD2 1 
ATOM   6833 C CE1 . TYR D 2 19  ? -35.011 7.606   36.952  1   70.54  ? 15  TYR C CE1 1 
ATOM   6834 C CE2 . TYR D 2 19  ? -32.683 7.069   36.979  1   64.32  ? 15  TYR C CE2 1 
ATOM   6835 C CZ  . TYR D 2 19  ? -33.911 7.027   36.354  1   66.16  ? 15  TYR C CZ  1 
ATOM   6836 O OH  . TYR D 2 19  ? -33.999 6.414   35.148  1   67.61  ? 15  TYR C OH  1 
ATOM   6837 N N   . GLY D 2 20  ? -31.029 11.057  39.815  1   87.92  ? 16  GLY C N   1 
ATOM   6838 C CA  . GLY D 2 20  ? -29.828 11.334  39.023  1   83.81  ? 16  GLY C CA  1 
ATOM   6839 C C   . GLY D 2 20  ? -29.556 12.795  38.776  1   81.05  ? 16  GLY C C   1 
ATOM   6840 O O   . GLY D 2 20  ? -30.411 13.62   39.108  1   79.75  ? 16  GLY C O   1 
ATOM   6841 N N   . VAL D 2 21  ? -28.37  13.094  38.252  1   80.82  ? 17  VAL C N   1 
ATOM   6842 C CA  . VAL D 2 21  ? -28.017 14.469  37.826  1   67.84  ? 17  VAL C CA  1 
ATOM   6843 C C   . VAL D 2 21  ? -27.944 14.406  36.296  1   62.06  ? 17  VAL C C   1 
ATOM   6844 O O   . VAL D 2 21  ? -27.396 13.431  35.776  1   63.15  ? 17  VAL C O   1 
ATOM   6845 C CB  . VAL D 2 21  ? -26.697 14.98   38.422  1   65.23  ? 17  VAL C CB  1 
ATOM   6846 C CG1 . VAL D 2 21  ? -26.516 16.472  38.185  1   62.59  ? 17  VAL C CG1 1 
ATOM   6847 C CG2 . VAL D 2 21  ? -26.581 14.645  39.901  1   69.55  ? 17  VAL C CG2 1 
ATOM   6848 N N   . VAL D 2 22  ? -28.533 15.388  35.627  1   53.78  ? 18  VAL C N   1 
ATOM   6849 C CA  . VAL D 2 22  ? -28.488 15.431  34.175  1   47.22  ? 18  VAL C CA  1 
ATOM   6850 C C   . VAL D 2 22  ? -27.587 16.57   33.723  1   48.8   ? 18  VAL C C   1 
ATOM   6851 O O   . VAL D 2 22  ? -27.761 17.713  34.156  1   49.02  ? 18  VAL C O   1 
ATOM   6852 C CB  . VAL D 2 22  ? -29.884 15.525  33.551  1   42.34  ? 18  VAL C CB  1 
ATOM   6853 C CG1 . VAL D 2 22  ? -29.843 16.05   32.138  1   38.69  ? 18  VAL C CG1 1 
ATOM   6854 C CG2 . VAL D 2 22  ? -30.55  14.168  33.552  1   48.12  ? 18  VAL C CG2 1 
ATOM   6855 N N   . TYR D 2 23  ? -26.635 16.225  32.842  1   47.77  ? 19  TYR C N   1 
ATOM   6856 C CA  . TYR D 2 23  ? -25.728 17.192  32.249  1   46.24  ? 19  TYR C CA  1 
ATOM   6857 C C   . TYR D 2 23  ? -25.923 17.23   30.743  1   43.56  ? 19  TYR C C   1 
ATOM   6858 O O   . TYR D 2 23  ? -26.424 16.278  30.152  1   42.05  ? 19  TYR C O   1 
ATOM   6859 C CB  . TYR D 2 23  ? -24.27  16.805  32.437  1   48.78  ? 19  TYR C CB  1 
ATOM   6860 C CG  . TYR D 2 23  ? -23.889 16.441  33.856  1   52.65  ? 19  TYR C CG  1 
ATOM   6861 C CD1 . TYR D 2 23  ? -24.116 15.152  34.341  1   54.47  ? 19  TYR C CD1 1 
ATOM   6862 C CD2 . TYR D 2 23  ? -23.259 17.369  34.675  1   55.27  ? 19  TYR C CD2 1 
ATOM   6863 C CE1 . TYR D 2 23  ? -23.739 14.793  35.623  1   60.65  ? 19  TYR C CE1 1 
ATOM   6864 C CE2 . TYR D 2 23  ? -22.866 17.018  35.956  1   63.61  ? 19  TYR C CE2 1 
ATOM   6865 C CZ  . TYR D 2 23  ? -23.103 15.731  36.426  1   68.41  ? 19  TYR C CZ  1 
ATOM   6866 O OH  . TYR D 2 23  ? -22.715 15.385  37.694  1   76.5   ? 19  TYR C OH  1 
ATOM   6867 N N   . LYS D 2 24  ? -25.503 18.359  30.16   1   42.71  ? 20  LYS C N   1 
ATOM   6868 C CA  . LYS D 2 24  ? -25.502 18.601  28.729  1   39.87  ? 20  LYS C CA  1 
ATOM   6869 C C   . LYS D 2 24  ? -24.096 18.333  28.218  1   39.59  ? 20  LYS C C   1 
ATOM   6870 O O   . LYS D 2 24  ? -23.126 18.716  28.858  1   39.74  ? 20  LYS C O   1 
ATOM   6871 C CB  . LYS D 2 24  ? -25.85  20.062  28.45   1   41.06  ? 20  LYS C CB  1 
ATOM   6872 C CG  . LYS D 2 24  ? -25.58  20.522  27.039  1   43.19  ? 20  LYS C CG  1 
ATOM   6873 C CD  . LYS D 2 24  ? -26.153 21.882  26.691  1   43.1   ? 20  LYS C CD  1 
ATOM   6874 C CE  . LYS D 2 24  ? -25.987 22.185  25.233  1   45.67  ? 20  LYS C CE  1 
ATOM   6875 N NZ  . LYS D 2 24  ? -26.713 23.412  24.875  1   47.56  ? 20  LYS C NZ  1 
ATOM   6876 N N   . ALA D 2 25  ? -24.001 17.633  27.085  1   38.95  ? 21  ALA C N   1 
ATOM   6877 C CA  . ALA D 2 25  ? -22.725 17.1    26.637  1   40.57  ? 21  ALA C CA  1 
ATOM   6878 C C   . ALA D 2 25  ? -22.671 17.131  25.118  1   42.73  ? 21  ALA C C   1 
ATOM   6879 O O   . ALA D 2 25  ? -23.711 17.216  24.447  1   41.25  ? 21  ALA C O   1 
ATOM   6880 C CB  . ALA D 2 25  ? -22.558 15.683  27.119  1   38.74  ? 21  ALA C CB  1 
ATOM   6881 N N   . ARG D 2 26  ? -21.435 17.005  24.611  1   44.61  ? 22  ARG C N   1 
ATOM   6882 C CA  . ARG D 2 26  ? -21.146 16.952  23.191  1   46.09  ? 22  ARG C CA  1 
ATOM   6883 C C   . ARG D 2 26  ? -20.327 15.69   22.917  1   45.52  ? 22  ARG C C   1 
ATOM   6884 O O   . ARG D 2 26  ? -19.325 15.443  23.58   1   47.58  ? 22  ARG C O   1 
ATOM   6885 C CB  . ARG D 2 26  ? -20.396 18.238  22.838  1   52.42  ? 22  ARG C CB  1 
ATOM   6886 C CG  . ARG D 2 26  ? -20.632 18.815  21.45   1   61.05  ? 22  ARG C CG  1 
ATOM   6887 C CD  . ARG D 2 26  ? -19.861 20.122  21.261  1   70.09  ? 22  ARG C CD  1 
ATOM   6888 N NE  . ARG D 2 26  ? -18.454 19.771  21.008  1   79.94  ? 22  ARG C NE  1 
ATOM   6889 C CZ  . ARG D 2 26  ? -17.448 19.717  21.899  1   83     ? 22  ARG C CZ  1 
ATOM   6890 N NH1 . ARG D 2 26  ? -17.605 20.099  23.154  1   81.03  ? 22  ARG C NH1 1 
ATOM   6891 N NH2 . ARG D 2 26  ? -16.269 19.261  21.534  1   84.86  ? 22  ARG C NH2 1 
ATOM   6892 N N   . ASN D 2 27  ? -20.793 14.866  21.972  1   42.34  ? 23  ASN C N   1 
ATOM   6893 C CA  . ASN D 2 27  ? -19.993 13.788  21.419  1   41.69  ? 23  ASN C CA  1 
ATOM   6894 C C   . ASN D 2 27  ? -18.842 14.407  20.637  1   43.59  ? 23  ASN C C   1 
ATOM   6895 O O   . ASN D 2 27  ? -19.062 15.078  19.641  1   44.6   ? 23  ASN C O   1 
ATOM   6896 C CB  . ASN D 2 27  ? -20.816 12.921  20.47   1   40.63  ? 23  ASN C CB  1 
ATOM   6897 C CG  . ASN D 2 27  ? -20.163 11.599  20.112  1   40.42  ? 23  ASN C CG  1 
ATOM   6898 O OD1 . ASN D 2 27  ? -19.042 11.549  19.596  1   41.17  ? 23  ASN C OD1 1 
ATOM   6899 N ND2 . ASN D 2 27  ? -20.868 10.511  20.369  1   38.85  ? 23  ASN C ND2 1 
ATOM   6900 N N   . LYS D 2 28  ? -17.617 14.145  21.081  1   44.92  ? 24  LYS C N   1 
ATOM   6901 C CA  . LYS D 2 28  ? -16.419 14.727  20.508  1   47.62  ? 24  LYS C CA  1 
ATOM   6902 C C   . LYS D 2 28  ? -16.169 14.227  19.088  1   48.95  ? 24  LYS C C   1 
ATOM   6903 O O   . LYS D 2 28  ? -15.443 14.873  18.326  1   51.3   ? 24  LYS C O   1 
ATOM   6904 C CB  . LYS D 2 28  ? -15.211 14.291  21.337  1   49.61  ? 24  LYS C CB  1 
ATOM   6905 C CG  . LYS D 2 28  ? -15.177 14.79   22.758  1   50.1   ? 24  LYS C CG  1 
ATOM   6906 C CD  . LYS D 2 28  ? -13.861 14.401  23.412  1   54.04  ? 24  LYS C CD  1 
ATOM   6907 C CE  . LYS D 2 28  ? -14.014 14.282  24.909  1   55.75  ? 24  LYS C CE  1 
ATOM   6908 N NZ  . LYS D 2 28  ? -12.854 13.622  25.519  1   60.02  ? 24  LYS C NZ  1 
ATOM   6909 N N   . LEU D 2 29  ? -16.74  13.071  18.745  1   48.02  ? 25  LEU C N   1 
ATOM   6910 C CA  . LEU D 2 29  ? -16.438 12.468  17.42   1   49.6   ? 25  LEU C CA  1 
ATOM   6911 C C   . LEU D 2 29  ? -17.483 12.89   16.377  1   49.24  ? 25  LEU C C   1 
ATOM   6912 O O   . LEU D 2 29  ? -17.089 13.105  15.214  1   50.65  ? 25  LEU C O   1 
ATOM   6913 C CB  . LEU D 2 29  ? -16.375 10.951  17.579  1   48.3   ? 25  LEU C CB  1 
ATOM   6914 C CG  . LEU D 2 29  ? -15.055 10.399  18.125  1   49.51  ? 25  LEU C CG  1 
ATOM   6915 C CD1 . LEU D 2 29  ? -15.164 8.909   18.374  1   49.05  ? 25  LEU C CD1 1 
ATOM   6916 C CD2 . LEU D 2 29  ? -13.913 10.702  17.171  1   51.65  ? 25  LEU C CD2 1 
ATOM   6917 N N   . THR D 2 30  ? -18.755 12.993  16.766  1   46.71  ? 26  THR C N   1 
ATOM   6918 C CA  . THR D 2 30  ? -19.81  13.304  15.775  1   46.23  ? 26  THR C CA  1 
ATOM   6919 C C   . THR D 2 30  ? -20.294 14.725  15.966  1   46.49  ? 26  THR C C   1 
ATOM   6920 O O   . THR D 2 30  ? -21.003 15.229  15.066  1   47.37  ? 26  THR C O   1 
ATOM   6921 C CB  . THR D 2 30  ? -20.948 12.296  15.918  1   45.25  ? 26  THR C CB  1 
ATOM   6922 O OG1 . THR D 2 30  ? -21.566 12.618  17.159  1   43.54  ? 26  THR C OG1 1 
ATOM   6923 C CG2 . THR D 2 30  ? -20.459 10.859  15.94   1   45.58  ? 26  THR C CG2 1 
ATOM   6924 N N   . GLY D 2 31  ? -19.942 15.355  17.091  1   45.99  ? 27  GLY C N   1 
ATOM   6925 C CA  . GLY D 2 31  ? -20.431 16.717  17.388  1   46.91  ? 27  GLY C CA  1 
ATOM   6926 C C   . GLY D 2 31  ? -21.856 16.675  17.902  1   45.92  ? 27  GLY C C   1 
ATOM   6927 O O   . GLY D 2 31  ? -22.446 17.758  18.094  1   45.3   ? 27  GLY C O   1 
ATOM   6928 N N   . GLU D 2 32  ? -22.392 15.473  18.136  1   44.7   ? 28  GLU C N   1 
ATOM   6929 C CA  . GLU D 2 32  ? -23.809 15.338  18.561  1   42.76  ? 28  GLU C CA  1 
ATOM   6930 C C   . GLU D 2 32  ? -23.987 15.878  19.987  1   40.85  ? 28  GLU C C   1 
ATOM   6931 O O   . GLU D 2 32  ? -23.257 15.42   20.891  1   41.73  ? 28  GLU C O   1 
ATOM   6932 C CB  . GLU D 2 32  ? -24.253 13.877  18.495  1   43.14  ? 28  GLU C CB  1 
ATOM   6933 C CG  . GLU D 2 32  ? -25.697 13.678  18.939  1   43.39  ? 28  GLU C CG  1 
ATOM   6934 C CD  . GLU D 2 32  ? -26.18  12.244  18.851  1   45.29  ? 28  GLU C CD  1 
ATOM   6935 O OE1 . GLU D 2 32  ? -25.355 11.342  18.591  1   48.74  ? 28  GLU C OE1 1 
ATOM   6936 O OE2 . GLU D 2 32  ? -27.396 12.037  19.036  1   42.84  ? 28  GLU C OE2 1 
ATOM   6937 N N   . VAL D 2 33  ? -24.928 16.807  20.176  1   39.21  ? 29  VAL C N   1 
ATOM   6938 C CA  . VAL D 2 33  ? -25.203 17.332  21.507  1   37.79  ? 29  VAL C CA  1 
ATOM   6939 C C   . VAL D 2 33  ? -26.213 16.408  22.187  1   36.2   ? 29  VAL C C   1 
ATOM   6940 O O   . VAL D 2 33  ? -27.2   16.012  21.577  1   36.12  ? 29  VAL C O   1 
ATOM   6941 C CB  . VAL D 2 33  ? -25.666 18.807  21.454  1   36.23  ? 29  VAL C CB  1 
ATOM   6942 C CG1 . VAL D 2 33  ? -26.159 19.317  22.804  1   34.73  ? 29  VAL C CG1 1 
ATOM   6943 C CG2 . VAL D 2 33  ? -24.544 19.702  20.947  1   37.64  ? 29  VAL C CG2 1 
ATOM   6944 N N   . VAL D 2 34  ? -25.951 16.046  23.446  1   35.8   ? 30  VAL C N   1 
ATOM   6945 C CA  . VAL D 2 34  ? -26.793 15.067  24.118  1   35.3   ? 30  VAL C CA  1 
ATOM   6946 C C   . VAL D 2 34  ? -27.03  15.516  25.551  1   35.94  ? 30  VAL C C   1 
ATOM   6947 O O   . VAL D 2 34  ? -26.457 16.518  25.994  1   40.35  ? 30  VAL C O   1 
ATOM   6948 C CB  . VAL D 2 34  ? -26.173 13.659  24.041  1   35.33  ? 30  VAL C CB  1 
ATOM   6949 C CG1 . VAL D 2 34  ? -26.067 13.187  22.579  1   35.96  ? 30  VAL C CG1 1 
ATOM   6950 C CG2 . VAL D 2 34  ? -24.825 13.575  24.76   1   35.12  ? 30  VAL C CG2 1 
ATOM   6951 N N   . ALA D 2 35  ? -27.925 14.811  26.248  1   33.61  ? 31  ALA C N   1 
ATOM   6952 C CA  . ALA D 2 35  ? -28.033 14.965  27.694  1   32.56  ? 31  ALA C CA  1 
ATOM   6953 C C   . ALA D 2 35  ? -27.765 13.609  28.326  1   33.25  ? 31  ALA C C   1 
ATOM   6954 O O   . ALA D 2 35  ? -28.27  12.604  27.83   1   34.42  ? 31  ALA C O   1 
ATOM   6955 C CB  . ALA D 2 35  ? -29.394 15.461  28.065  1   30.36  ? 31  ALA C CB  1 
ATOM   6956 N N   . LEU D 2 36  ? -26.915 13.581  29.36   1   33.3   ? 32  LEU C N   1 
ATOM   6957 C CA  . LEU D 2 36  ? -26.553 12.343  30.028  1   33.62  ? 32  LEU C CA  1 
ATOM   6958 C C   . LEU D 2 36  ? -27.139 12.357  31.436  1   35.83  ? 32  LEU C C   1 
ATOM   6959 O O   . LEU D 2 36  ? -26.648 13.096  32.281  1   41.06  ? 32  LEU C O   1 
ATOM   6960 C CB  . LEU D 2 36  ? -25.03  12.327  30.111  1   33.58  ? 32  LEU C CB  1 
ATOM   6961 C CG  . LEU D 2 36  ? -24.251 12.517  28.812  1   33.23  ? 32  LEU C CG  1 
ATOM   6962 C CD1 . LEU D 2 36  ? -22.836 12.951  29.189  1   34.07  ? 32  LEU C CD1 1 
ATOM   6963 C CD2 . LEU D 2 36  ? -24.216 11.23   27.987  1   32.11  ? 32  LEU C CD2 1 
ATOM   6964 N N   . LYS D 2 37  ? -28.196 11.579  31.693  1   35.78  ? 33  LYS C N   1 
ATOM   6965 C CA  . LYS D 2 37  ? -28.618 11.278  33.058  1   36.71  ? 33  LYS C CA  1 
ATOM   6966 C C   . LYS D 2 37  ? -27.621 10.269  33.634  1   39.65  ? 33  LYS C C   1 
ATOM   6967 O O   . LYS D 2 37  ? -27.378 9.236   33.006  1   40.08  ? 33  LYS C O   1 
ATOM   6968 C CB  . LYS D 2 37  ? -30.071 10.791  33.004  1   34.98  ? 33  LYS C CB  1 
ATOM   6969 C CG  . LYS D 2 37  ? -30.809 10.508  34.298  1   36.81  ? 33  LYS C CG  1 
ATOM   6970 C CD  . LYS D 2 37  ? -32.287 10.132  34.183  1   38.83  ? 33  LYS C CD  1 
ATOM   6971 C CE  . LYS D 2 37  ? -33.261 11.24   33.815  1   45.68  ? 33  LYS C CE  1 
ATOM   6972 N NZ  . LYS D 2 37  ? -34.694 10.882  33.827  1   46.72  ? 33  LYS C NZ  1 
ATOM   6973 N N   . LYS D 2 38  ? -26.987 10.622  34.767  1   42.77  ? 34  LYS C N   1 
ATOM   6974 C CA  . LYS D 2 38  ? -25.97  9.825   35.454  1   45.33  ? 34  LYS C CA  1 
ATOM   6975 C C   . LYS D 2 38  ? -26.608 9.246   36.71   1   47.22  ? 34  LYS C C   1 
ATOM   6976 O O   . LYS D 2 38  ? -27.06  10.004  37.554  1   50.61  ? 34  LYS C O   1 
ATOM   6977 C CB  . LYS D 2 38  ? -24.821 10.736  35.903  1   48.27  ? 34  LYS C CB  1 
ATOM   6978 C CG  . LYS D 2 38  ? -23.636 10.086  36.573  1   54.31  ? 34  LYS C CG  1 
ATOM   6979 C CD  . LYS D 2 38  ? -22.508 11.02   37.008  1   63.9   ? 34  LYS C CD  1 
ATOM   6980 C CE  . LYS D 2 38  ? -22.946 11.932  38.152  1   77.31  ? 34  LYS C CE  1 
ATOM   6981 N NZ  . LYS D 2 38  ? -23.279 11.307  39.449  1   77.6   ? 34  LYS C NZ  1 
ATOM   6982 N N   . ILE D 2 39  ? -26.695 7.912   36.82   1   50.36  ? 35  ILE C N   1 
ATOM   6983 C CA  . ILE D 2 39  ? -27.439 7.269   37.907  1   50.79  ? 35  ILE C CA  1 
ATOM   6984 C C   . ILE D 2 39  ? -26.464 6.476   38.757  1   50.98  ? 35  ILE C C   1 
ATOM   6985 O O   . ILE D 2 39  ? -25.91  5.499   38.271  1   51.03  ? 35  ILE C O   1 
ATOM   6986 C CB  . ILE D 2 39  ? -28.513 6.29    37.402  1   48.4   ? 35  ILE C CB  1 
ATOM   6987 C CG1 . ILE D 2 39  ? -29.151 6.722   36.109  1   50.1   ? 35  ILE C CG1 1 
ATOM   6988 C CG2 . ILE D 2 39  ? -29.561 6.048   38.469  1   50.62  ? 35  ILE C CG2 1 
ATOM   6989 C CD1 . ILE D 2 39  ? -29.758 5.567   35.321  1   51.88  ? 35  ILE C CD1 1 
ATOM   6990 N N   . ARG D 2 40  ? -26.293 6.898   40.015  1   55.82  ? 36  ARG C N   1 
ATOM   6991 C CA  . ARG D 2 40  ? -25.327 6.29    40.922  1   59.26  ? 36  ARG C CA  1 
ATOM   6992 C C   . ARG D 2 40  ? -25.886 4.952   41.411  1   55.22  ? 36  ARG C C   1 
ATOM   6993 O O   . ARG D 2 40  ? -27.035 4.889   41.84   1   50.9   ? 36  ARG C O   1 
ATOM   6994 C CB  . ARG D 2 40  ? -24.984 7.289   42.033  1   64.79  ? 36  ARG C CB  1 
ATOM   6995 C CG  . ARG D 2 40  ? -23.812 6.896   42.921  1   80.84  ? 36  ARG C CG  1 
ATOM   6996 C CD  . ARG D 2 40  ? -22.454 7.183   42.289  1   95.46  ? 36  ARG C CD  1 
ATOM   6997 N NE  . ARG D 2 40  ? -21.339 6.913   43.208  1   106.1  ? 36  ARG C NE  1 
ATOM   6998 C CZ  . ARG D 2 40  ? -20.381 6.007   43.026  1   112.62 ? 36  ARG C CZ  1 
ATOM   6999 N NH1 . ARG D 2 40  ? -19.423 5.861   43.928  1   109.67 ? 36  ARG C NH1 1 
ATOM   7000 N NH2 . ARG D 2 40  ? -20.374 5.25    41.939  1   121.35 ? 36  ARG C NH2 1 
ATOM   7001 N N   . LEU D 2 41  ? -25.077 3.891   41.307  1   54.84  ? 37  LEU C N   1 
ATOM   7002 C CA  . LEU D 2 41  ? -25.51  2.556   41.705  1   56.47  ? 37  LEU C CA  1 
ATOM   7003 C C   . LEU D 2 41  ? -24.991 2.257   43.111  1   61.65  ? 37  LEU C C   1 
ATOM   7004 O O   . LEU D 2 41  ? -23.888 2.679   43.465  1   66.37  ? 37  LEU C O   1 
ATOM   7005 C CB  . LEU D 2 41  ? -25.11  1.448   40.73   1   51.42  ? 37  LEU C CB  1 
ATOM   7006 C CG  . LEU D 2 41  ? -25.251 1.746   39.236  1   47.11  ? 37  LEU C CG  1 
ATOM   7007 C CD1 . LEU D 2 41  ? -23.94  2.266   38.763  1   50.16  ? 37  LEU C CD1 1 
ATOM   7008 C CD2 . LEU D 2 41  ? -25.556 0.528   38.418  1   44.93  ? 37  LEU C CD2 1 
ATOM   7009 N N   . ASP D 2 42  ? -25.781 1.518   43.904  1   59.32  ? 38  ASP C N   1 
ATOM   7010 C CA  . ASP D 2 42  ? -25.386 1.187   45.266  1   61.33  ? 38  ASP C CA  1 
ATOM   7011 C C   . ASP D 2 42  ? -24.86  -0.245  45.274  1   58.2   ? 38  ASP C C   1 
ATOM   7012 O O   . ASP D 2 42  ? -25.609 -1.171  45.559  1   61.7   ? 38  ASP C O   1 
ATOM   7013 C CB  . ASP D 2 42  ? -26.559 1.349   46.224  1   68.66  ? 38  ASP C CB  1 
ATOM   7014 C CG  . ASP D 2 42  ? -27.376 2.622   46.045  1   76.82  ? 38  ASP C CG  1 
ATOM   7015 O OD1 . ASP D 2 42  ? -26.78  3.712   46.187  1   86.76  ? 38  ASP C OD1 1 
ATOM   7016 O OD2 . ASP D 2 42  ? -28.59  2.514   45.744  1   76.35  ? 38  ASP C OD2 1 
ATOM   7017 N N   . THR D 2 43  ? -23.573 -0.426  44.97   1   53.41  ? 39  THR C N   1 
ATOM   7018 C CA  . THR D 2 43  ? -23.057 -1.724  44.568  1   51.54  ? 39  THR C CA  1 
ATOM   7019 C C   . THR D 2 43  ? -22.76  -2.625  45.768  1   53.71  ? 39  THR C C   1 
ATOM   7020 O O   . THR D 2 43  ? -22.232 -3.73   45.598  1   55.91  ? 39  THR C O   1 
ATOM   7021 C CB  . THR D 2 43  ? -21.817 -1.52   43.705  1   52.1   ? 39  THR C CB  1 
ATOM   7022 O OG1 . THR D 2 43  ? -20.797 -0.98   44.538  1   56.09  ? 39  THR C OG1 1 
ATOM   7023 C CG2 . THR D 2 43  ? -22.064 -0.607  42.522  1   48.6   ? 39  THR C CG2 1 
ATOM   7024 N N   . GLU D 2 44  ? -23.04  -2.136  46.981  1   53.19  ? 40  GLU C N   1 
ATOM   7025 C CA  . GLU D 2 44  ? -22.913 -2.947  48.182  1   53.77  ? 40  GLU C CA  1 
ATOM   7026 C C   . GLU D 2 44  ? -24.27  -3.026  48.873  1   53.1   ? 40  GLU C C   1 
ATOM   7027 O O   . GLU D 2 44  ? -24.379 -3.643  49.923  1   56.77  ? 40  GLU C O   1 
ATOM   7028 C CB  . GLU D 2 44  ? -21.913 -2.357  49.18   1   54.35  ? 40  GLU C CB  1 
ATOM   7029 C CG  . GLU D 2 44  ? -20.452 -2.379  48.738  1   55.39  ? 40  GLU C CG  1 
ATOM   7030 C CD  . GLU D 2 44  ? -20.07  -1.56   47.511  1   53.85  ? 40  GLU C CD  1 
ATOM   7031 O OE1 . GLU D 2 44  ? -19.365 -2.086  46.628  1   54.51  ? 40  GLU C OE1 1 
ATOM   7032 O OE2 . GLU D 2 44  ? -20.491 -0.398  47.409  1   51.84  ? 40  GLU C OE2 1 
ATOM   7033 N N   . THR D 2 45  ? -25.293 -2.376  48.311  1   50.38  ? 41  THR C N   1 
ATOM   7034 C CA  . THR D 2 45  ? -26.52  -2.136  49.058  1   50.03  ? 41  THR C CA  1 
ATOM   7035 C C   . THR D 2 45  ? -27.76  -2.525  48.253  1   47.99  ? 41  THR C C   1 
ATOM   7036 O O   . THR D 2 45  ? -28.233 -3.642  48.395  1   49.93  ? 41  THR C O   1 
ATOM   7037 C CB  . THR D 2 45  ? -26.554 -0.748  49.707  1   50.22  ? 41  THR C CB  1 
ATOM   7038 O OG1 . THR D 2 45  ? -25.931 0.248   48.897  1   50.07  ? 41  THR C OG1 1 
ATOM   7039 C CG2 . THR D 2 45  ? -25.783 -0.74   51.015  1   52.21  ? 41  THR C CG2 1 
ATOM   7040 N N   . GLU D 2 46  ? -28.292 -1.629  47.422  1   46.47  ? 42  GLU C N   1 
ATOM   7041 C CA  . GLU D 2 46  ? -29.561 -1.905  46.772  1   46.75  ? 42  GLU C CA  1 
ATOM   7042 C C   . GLU D 2 46  ? -29.376 -2.166  45.279  1   43.02  ? 42  GLU C C   1 
ATOM   7043 O O   . GLU D 2 46  ? -30.349 -2.441  44.592  1   41.83  ? 42  GLU C O   1 
ATOM   7044 C CB  . GLU D 2 46  ? -30.535 -0.73   46.876  1   50.18  ? 42  GLU C CB  1 
ATOM   7045 C CG  . GLU D 2 46  ? -31.013 -0.453  48.298  1   59.07  ? 42  GLU C CG  1 
ATOM   7046 C CD  . GLU D 2 46  ? -31.928 0.737   48.52   1   68.18  ? 42  GLU C CD  1 
ATOM   7047 O OE1 . GLU D 2 46  ? -32.021 1.482   47.495  1   66.92  ? 42  GLU C OE1 1 
ATOM   7048 O OE2 . GLU D 2 46  ? -32.486 0.939   49.651  1   71.38  ? 42  GLU C OE2 1 
ATOM   7049 N N   . GLY D 2 47  ? -28.151 -2.058  44.77   1   41.48  ? 43  GLY C N   1 
ATOM   7050 C CA  . GLY D 2 47  ? -27.926 -2.217  43.342  1   40.33  ? 43  GLY C CA  1 
ATOM   7051 C C   . GLY D 2 47  ? -28.701 -1.186  42.521  1   38.88  ? 43  GLY C C   1 
ATOM   7052 O O   . GLY D 2 47  ? -28.948 -0.069  42.986  1   40.24  ? 43  GLY C O   1 
ATOM   7053 N N   . VAL D 2 48  ? -29.083 -1.584  41.298  1   36.66  ? 44  VAL C N   1 
ATOM   7054 C CA  . VAL D 2 48  ? -29.628 -0.681  40.297  1   34.82  ? 44  VAL C CA  1 
ATOM   7055 C C   . VAL D 2 48  ? -31.026 -0.27   40.732  1   35.71  ? 44  VAL C C   1 
ATOM   7056 O O   . VAL D 2 48  ? -31.872 -1.136  40.93   1   35.44  ? 44  VAL C O   1 
ATOM   7057 C CB  . VAL D 2 48  ? -29.703 -1.346  38.91   1   33.01  ? 44  VAL C CB  1 
ATOM   7058 C CG1 . VAL D 2 48  ? -30.151 -0.366  37.823  1   30.52  ? 44  VAL C CG1 1 
ATOM   7059 C CG2 . VAL D 2 48  ? -28.398 -2.032  38.533  1   33.54  ? 44  VAL C CG2 1 
ATOM   7060 N N   . PRO D 2 49  ? -31.322 1.048   40.85   1   37.44  ? 45  PRO C N   1 
ATOM   7061 C CA  . PRO D 2 49  ? -32.616 1.521   41.347  1   37.34  ? 45  PRO C CA  1 
ATOM   7062 C C   . PRO D 2 49  ? -33.775 1.118   40.445  1   38.93  ? 45  PRO C C   1 
ATOM   7063 O O   . PRO D 2 49  ? -33.671 1.206   39.217  1   38.98  ? 45  PRO C O   1 
ATOM   7064 C CB  . PRO D 2 49  ? -32.534 3.047   41.418  1   35.08  ? 45  PRO C CB  1 
ATOM   7065 C CG  . PRO D 2 49  ? -31.1   3.355   41.156  1   37.09  ? 45  PRO C CG  1 
ATOM   7066 C CD  . PRO D 2 49  ? -30.439 2.162   40.473  1   38.39  ? 45  PRO C CD  1 
ATOM   7067 N N   . SER D 2 50  ? -34.9   0.77    41.093  1   40.1   ? 46  SER C N   1 
ATOM   7068 C CA  . SER D 2 50  ? -36.129 0.381   40.427  1   37.91  ? 46  SER C CA  1 
ATOM   7069 C C   . SER D 2 50  ? -36.583 1.46    39.435  1   35.33  ? 46  SER C C   1 
ATOM   7070 O O   . SER D 2 50  ? -37.084 1.11    38.369  1   34.11  ? 46  SER C O   1 
ATOM   7071 C CB  . SER D 2 50  ? -37.191 0.006   41.446  1   38.87  ? 46  SER C CB  1 
ATOM   7072 O OG  . SER D 2 50  ? -37.943 1.143   41.841  1   40.32  ? 46  SER C OG  1 
ATOM   7073 N N   . THR D 2 51  ? -36.397 2.753   39.772  1   33.73  ? 47  THR C N   1 
ATOM   7074 C CA  . THR D 2 51  ? -36.818 3.842   38.892  1   33.4   ? 47  THR C CA  1 
ATOM   7075 C C   . THR D 2 51  ? -36.049 3.791   37.575  1   32.81  ? 47  THR C C   1 
ATOM   7076 O O   . THR D 2 51  ? -36.588 4.143   36.529  1   34.25  ? 47  THR C O   1 
ATOM   7077 C CB  . THR D 2 51  ? -36.691 5.239   39.49   1   33.46  ? 47  THR C CB  1 
ATOM   7078 O OG1 . THR D 2 51  ? -35.367 5.227   39.984  1   38.71  ? 47  THR C OG1 1 
ATOM   7079 C CG2 . THR D 2 51  ? -37.662 5.549   40.614  1   35.67  ? 47  THR C CG2 1 
ATOM   7080 N N   . ALA D 2 52  ? -34.795 3.344   37.632  1   32.34  ? 48  ALA C N   1 
ATOM   7081 C CA  . ALA D 2 52  ? -33.919 3.35    36.476  1   31.86  ? 48  ALA C CA  1 
ATOM   7082 C C   . ALA D 2 52  ? -34.227 2.154   35.569  1   31.94  ? 48  ALA C C   1 
ATOM   7083 O O   . ALA D 2 52  ? -34.181 2.288   34.337  1   30.18  ? 48  ALA C O   1 
ATOM   7084 C CB  . ALA D 2 52  ? -32.481 3.37    36.942  1   31.95  ? 48  ALA C CB  1 
ATOM   7085 N N   . ILE D 2 53  ? -34.537 1.006   36.212  1   30.78  ? 49  ILE C N   1 
ATOM   7086 C CA  . ILE D 2 53  ? -34.944 -0.22   35.543  1   30.29  ? 49  ILE C CA  1 
ATOM   7087 C C   . ILE D 2 53  ? -36.232 -0.001  34.746  1   30.7   ? 49  ILE C C   1 
ATOM   7088 O O   . ILE D 2 53  ? -36.396 -0.55   33.661  1   31.56  ? 49  ILE C O   1 
ATOM   7089 C CB  . ILE D 2 53  ? -35.109 -1.367  36.552  1   29.39  ? 49  ILE C CB  1 
ATOM   7090 C CG1 . ILE D 2 53  ? -33.786 -1.789  37.134  1   29.81  ? 49  ILE C CG1 1 
ATOM   7091 C CG2 . ILE D 2 53  ? -35.808 -2.551  35.889  1   28.87  ? 49  ILE C CG2 1 
ATOM   7092 C CD1 . ILE D 2 53  ? -33.937 -2.703  38.339  1   30.83  ? 49  ILE C CD1 1 
ATOM   7093 N N   . ARG D 2 54  ? -37.153 0.792   35.296  1   31.23  ? 50  ARG C N   1 
ATOM   7094 C CA  . ARG D 2 54  ? -38.406 1.101   34.625  1   31.25  ? 50  ARG C CA  1 
ATOM   7095 C C   . ARG D 2 54  ? -38.169 2.1     33.493  1   31.18  ? 50  ARG C C   1 
ATOM   7096 O O   . ARG D 2 54  ? -38.625 1.865   32.379  1   30.22  ? 50  ARG C O   1 
ATOM   7097 C CB  . ARG D 2 54  ? -39.436 1.631   35.635  1   30.64  ? 50  ARG C CB  1 
ATOM   7098 C CG  . ARG D 2 54  ? -40.015 0.522   36.512  1   30.98  ? 50  ARG C CG  1 
ATOM   7099 C CD  . ARG D 2 54  ? -41.143 1.041   37.37   1   29.82  ? 50  ARG C CD  1 
ATOM   7100 N NE  . ARG D 2 54  ? -41.644 0.046   38.315  1   30.52  ? 50  ARG C NE  1 
ATOM   7101 C CZ  . ARG D 2 54  ? -42.48  0.334   39.303  1   31.73  ? 50  ARG C CZ  1 
ATOM   7102 N NH1 . ARG D 2 54  ? -42.934 1.57    39.482  1   29.46  ? 50  ARG C NH1 1 
ATOM   7103 N NH2 . ARG D 2 54  ? -42.854 -0.636  40.124  1   33.98  ? 50  ARG C NH2 1 
ATOM   7104 N N   . GLU D 2 55  ? -37.46  3.191   33.772  1   31.05  ? 51  GLU C N   1 
ATOM   7105 C CA  . GLU D 2 55  ? -37.29  4.219   32.714  1   31.37  ? 51  GLU C CA  1 
ATOM   7106 C C   . GLU D 2 55  ? -36.536 3.606   31.526  1   32.75  ? 51  GLU C C   1 
ATOM   7107 O O   . GLU D 2 55  ? -36.999 3.794   30.388  1   31.93  ? 51  GLU C O   1 
ATOM   7108 C CB  . GLU D 2 55  ? -36.552 5.444   33.255  1   31.58  ? 51  GLU C CB  1 
ATOM   7109 C CG  . GLU D 2 55  ? -36.161 6.436   32.163  1   33.78  ? 51  GLU C CG  1 
ATOM   7110 C CD  . GLU D 2 55  ? -35.84  7.84    32.637  1   34.52  ? 51  GLU C CD  1 
ATOM   7111 O OE1 . GLU D 2 55  ? -36.628 8.762   32.343  1   34.27  ? 51  GLU C OE1 1 
ATOM   7112 O OE2 . GLU D 2 55  ? -34.793 8.015   33.292  1   33.01  ? 51  GLU C OE2 1 
ATOM   7113 N N   . ILE D 2 56  ? -35.468 2.844   31.777  1   34.14  ? 52  ILE C N   1 
ATOM   7114 C CA  . ILE D 2 56  ? -34.631 2.343   30.697  1   33.86  ? 52  ILE C CA  1 
ATOM   7115 C C   . ILE D 2 56  ? -35.436 1.383   29.832  1   37.39  ? 52  ILE C C   1 
ATOM   7116 O O   . ILE D 2 56  ? -35.45  1.529   28.608  1   42.41  ? 52  ILE C O   1 
ATOM   7117 C CB  . ILE D 2 56  ? -33.325 1.718   31.229  1   31.77  ? 52  ILE C CB  1 
ATOM   7118 C CG1 . ILE D 2 56  ? -32.476 2.771   31.973  1   30.4   ? 52  ILE C CG1 1 
ATOM   7119 C CG2 . ILE D 2 56  ? -32.548 1.043   30.1    1   30.61  ? 52  ILE C CG2 1 
ATOM   7120 C CD1 . ILE D 2 56  ? -31.302 2.239   32.767  1   29.97  ? 52  ILE C CD1 1 
ATOM   7121 N N   . SER D 2 57  ? -36.124 0.428   30.473  1   38.42  ? 53  SER C N   1 
ATOM   7122 C CA  . SER D 2 57  ? -36.83  -0.642  29.769  1   39.3   ? 53  SER C CA  1 
ATOM   7123 C C   . SER D 2 57  ? -37.995 -0.08   28.956  1   36.72  ? 53  SER C C   1 
ATOM   7124 O O   . SER D 2 57  ? -38.173 -0.427  27.794  1   35.53  ? 53  SER C O   1 
ATOM   7125 C CB  . SER D 2 57  ? -37.319 -1.706  30.723  1   41.74  ? 53  SER C CB  1 
ATOM   7126 O OG  . SER D 2 57  ? -38.281 -1.149  31.611  1   46.02  ? 53  SER C OG  1 
ATOM   7127 N N   . LEU D 2 58  ? -38.781 0.789   29.604  1   35.25  ? 54  LEU C N   1 
ATOM   7128 C CA  . LEU D 2 58  ? -39.985 1.348   29.024  1   33.42  ? 54  LEU C CA  1 
ATOM   7129 C C   . LEU D 2 58  ? -39.624 2.283   27.88   1   35.44  ? 54  LEU C C   1 
ATOM   7130 O O   . LEU D 2 58  ? -40.269 2.204   26.833  1   37.06  ? 54  LEU C O   1 
ATOM   7131 C CB  . LEU D 2 58  ? -40.821 2.019   30.106  1   30.51  ? 54  LEU C CB  1 
ATOM   7132 C CG  . LEU D 2 58  ? -41.446 1.041   31.11   1   30.3   ? 54  LEU C CG  1 
ATOM   7133 C CD1 . LEU D 2 58  ? -42.362 1.732   32.1    1   29.45  ? 54  LEU C CD1 1 
ATOM   7134 C CD2 . LEU D 2 58  ? -42.198 -0.111  30.43   1   31.17  ? 54  LEU C CD2 1 
ATOM   7135 N N   . LEU D 2 59  ? -38.573 3.101   28.07   1   35.24  ? 55  LEU C N   1 
ATOM   7136 C CA  . LEU D 2 59  ? -38.106 4.029   27.042  1   35.53  ? 55  LEU C CA  1 
ATOM   7137 C C   . LEU D 2 59  ? -37.43  3.337   25.857  1   38.57  ? 55  LEU C C   1 
ATOM   7138 O O   . LEU D 2 59  ? -37.139 4.001   24.86   1   39.66  ? 55  LEU C O   1 
ATOM   7139 C CB  . LEU D 2 59  ? -37.174 5.08    27.631  1   31.58  ? 55  LEU C CB  1 
ATOM   7140 C CG  . LEU D 2 59  ? -37.862 6.332   28.177  1   29.46  ? 55  LEU C CG  1 
ATOM   7141 C CD1 . LEU D 2 59  ? -36.815 7.346   28.556  1   30.06  ? 55  LEU C CD1 1 
ATOM   7142 C CD2 . LEU D 2 59  ? -38.864 6.949   27.234  1   28.11  ? 55  LEU C CD2 1 
ATOM   7143 N N   . LYS D 2 60  ? -37.132 2.036   25.97   1   39.76  ? 56  LYS C N   1 
ATOM   7144 C CA  . LYS D 2 60  ? -36.601 1.29    24.839  1   41.21  ? 56  LYS C CA  1 
ATOM   7145 C C   . LYS D 2 60  ? -37.755 0.805   23.97   1   45.82  ? 56  LYS C C   1 
ATOM   7146 O O   . LYS D 2 60  ? -37.621 0.708   22.756  1   51.14  ? 56  LYS C O   1 
ATOM   7147 C CB  . LYS D 2 60  ? -35.713 0.132   25.291  1   38.4   ? 56  LYS C CB  1 
ATOM   7148 C CG  . LYS D 2 60  ? -34.304 0.544   25.624  1   38.44  ? 56  LYS C CG  1 
ATOM   7149 C CD  . LYS D 2 60  ? -33.586 -0.444  26.53   1   40.17  ? 56  LYS C CD  1 
ATOM   7150 C CE  . LYS D 2 60  ? -33.488 -1.81   25.925  1   41.86  ? 56  LYS C CE  1 
ATOM   7151 N NZ  . LYS D 2 60  ? -32.654 -1.831  24.725  1   41.13  ? 56  LYS C NZ  1 
ATOM   7152 N N   . GLU D 2 61  ? -38.891 0.499   24.598  1   48.05  ? 57  GLU C N   1 
ATOM   7153 C CA  . GLU D 2 61  ? -40.075 0.12    23.847  1   51.99  ? 57  GLU C CA  1 
ATOM   7154 C C   . GLU D 2 61  ? -40.517 1.319   23.023  1   49.61  ? 57  GLU C C   1 
ATOM   7155 O O   . GLU D 2 61  ? -40.921 1.174   21.873  1   54.48  ? 57  GLU C O   1 
ATOM   7156 C CB  . GLU D 2 61  ? -41.292 -0.129  24.741  1   58.5   ? 57  GLU C CB  1 
ATOM   7157 C CG  . GLU D 2 61  ? -41.082 -1.135  25.865  1   64.39  ? 57  GLU C CG  1 
ATOM   7158 C CD  . GLU D 2 61  ? -41.345 -2.561  25.46   1   66.19  ? 57  GLU C CD  1 
ATOM   7159 O OE1 . GLU D 2 61  ? -42.289 -3.148  26.012  1   69.51  ? 57  GLU C OE1 1 
ATOM   7160 O OE2 . GLU D 2 61  ? -40.599 -3.076  24.611  1   74.07  ? 57  GLU C OE2 1 
ATOM   7161 N N   . LEU D 2 62  ? -40.458 2.49    23.659  1   45.89  ? 58  LEU C N   1 
ATOM   7162 C CA  . LEU D 2 62  ? -41.202 3.663   23.235  1   43.71  ? 58  LEU C CA  1 
ATOM   7163 C C   . LEU D 2 62  ? -40.351 4.461   22.258  1   43.37  ? 58  LEU C C   1 
ATOM   7164 O O   . LEU D 2 62  ? -39.408 5.135   22.647  1   42.13  ? 58  LEU C O   1 
ATOM   7165 C CB  . LEU D 2 62  ? -41.589 4.443   24.493  1   39.74  ? 58  LEU C CB  1 
ATOM   7166 C CG  . LEU D 2 62  ? -42.558 3.743   25.456  1   36.34  ? 58  LEU C CG  1 
ATOM   7167 C CD1 . LEU D 2 62  ? -42.759 4.535   26.728  1   37.08  ? 58  LEU C CD1 1 
ATOM   7168 C CD2 . LEU D 2 62  ? -43.895 3.471   24.795  1   33.38  ? 58  LEU C CD2 1 
ATOM   7169 N N   . ASN D 2 63  ? -40.669 4.306   20.973  1   47.7   ? 59  ASN C N   1 
ATOM   7170 C CA  . ASN D 2 63  ? -40.009 5.036   19.91   1   52.29  ? 59  ASN C CA  1 
ATOM   7171 C C   . ASN D 2 63  ? -41.078 5.809   19.163  1   50.35  ? 59  ASN C C   1 
ATOM   7172 O O   . ASN D 2 63  ? -41.792 5.248   18.334  1   54.32  ? 59  ASN C O   1 
ATOM   7173 C CB  . ASN D 2 63  ? -39.089 4.146   19.079  1   64.61  ? 59  ASN C CB  1 
ATOM   7174 C CG  . ASN D 2 63  ? -37.747 3.945   19.758  1   77.3   ? 59  ASN C CG  1 
ATOM   7175 O OD1 . ASN D 2 63  ? -37.439 2.839   20.22   1   71.44  ? 59  ASN C OD1 1 
ATOM   7176 N ND2 . ASN D 2 63  ? -36.951 5.006   19.866  1   82.61  ? 59  ASN C ND2 1 
ATOM   7177 N N   . HIS D 2 64  ? -41.209 7.08    19.552  1   44.97  ? 60  HIS C N   1 
ATOM   7178 C CA  . HIS D 2 64  ? -42.195 7.995   19.014  1   45.62  ? 60  HIS C CA  1 
ATOM   7179 C C   . HIS D 2 64  ? -41.578 9.388   19.016  1   47.22  ? 60  HIS C C   1 
ATOM   7180 O O   . HIS D 2 64  ? -40.767 9.723   19.882  1   49.48  ? 60  HIS C O   1 
ATOM   7181 C CB  . HIS D 2 64  ? -43.504 7.93    19.817  1   46.46  ? 60  HIS C CB  1 
ATOM   7182 C CG  . HIS D 2 64  ? -44.655 8.748   19.288  1   47.62  ? 60  HIS C CG  1 
ATOM   7183 N ND1 . HIS D 2 64  ? -44.856 10.082  19.584  1   46.51  ? 60  HIS C ND1 1 
ATOM   7184 C CD2 . HIS D 2 64  ? -45.698 8.382   18.522  1   48.2   ? 60  HIS C CD2 1 
ATOM   7185 C CE1 . HIS D 2 64  ? -45.971 10.497  19      1   48.05  ? 60  HIS C CE1 1 
ATOM   7186 N NE2 . HIS D 2 64  ? -46.499 9.48    18.349  1   48.11  ? 60  HIS C NE2 1 
ATOM   7187 N N   . PRO D 2 65  ? -41.952 10.259  18.056  1   46.18  ? 61  PRO C N   1 
ATOM   7188 C CA  . PRO D 2 65  ? -41.312 11.564  17.955  1   43.89  ? 61  PRO C CA  1 
ATOM   7189 C C   . PRO D 2 65  ? -41.732 12.554  19.036  1   40.03  ? 61  PRO C C   1 
ATOM   7190 O O   . PRO D 2 65  ? -41.053 13.551  19.181  1   40.86  ? 61  PRO C O   1 
ATOM   7191 C CB  . PRO D 2 65  ? -41.672 12.001  16.539  1   43.22  ? 61  PRO C CB  1 
ATOM   7192 C CG  . PRO D 2 65  ? -43.043 11.385  16.33   1   44.13  ? 61  PRO C CG  1 
ATOM   7193 C CD  . PRO D 2 65  ? -42.999 10.051  17.043  1   44.4   ? 61  PRO C CD  1 
ATOM   7194 N N   . ASN D 2 66  ? -42.808 12.258  19.786  1   39.43  ? 62  ASN C N   1 
ATOM   7195 C CA  . ASN D 2 66  ? -43.263 13.07   20.919  1   40.64  ? 62  ASN C CA  1 
ATOM   7196 C C   . ASN D 2 66  ? -42.952 12.399  22.262  1   42.62  ? 62  ASN C C   1 
ATOM   7197 O O   . ASN D 2 66  ? -43.581 12.725  23.273  1   40.53  ? 62  ASN C O   1 
ATOM   7198 C CB  . ASN D 2 66  ? -44.757 13.352  20.881  1   38.77  ? 62  ASN C CB  1 
ATOM   7199 C CG  . ASN D 2 66  ? -45.097 14.126  19.638  1   42.42  ? 62  ASN C CG  1 
ATOM   7200 O OD1 . ASN D 2 66  ? -45.857 13.648  18.787  1   44.43  ? 62  ASN C OD1 1 
ATOM   7201 N ND2 . ASN D 2 66  ? -44.507 15.305  19.499  1   43.2   ? 62  ASN C ND2 1 
ATOM   7202 N N   . ILE D 2 67  ? -41.996 11.45   22.246  1   39.5   ? 63  ILE C N   1 
ATOM   7203 C CA  . ILE D 2 67  ? -41.402 10.892  23.445  1   34.43  ? 63  ILE C CA  1 
ATOM   7204 C C   . ILE D 2 67  ? -39.892 11.022  23.305  1   34.75  ? 63  ILE C C   1 
ATOM   7205 O O   . ILE D 2 67  ? -39.34  10.621  22.289  1   37.25  ? 63  ILE C O   1 
ATOM   7206 C CB  . ILE D 2 67  ? -41.815 9.42    23.583  1   33.43  ? 63  ILE C CB  1 
ATOM   7207 C CG1 . ILE D 2 67  ? -43.294 9.294   23.772  1   33.51  ? 63  ILE C CG1 1 
ATOM   7208 C CG2 . ILE D 2 67  ? -41.049 8.723   24.705  1   32.07  ? 63  ILE C CG2 1 
ATOM   7209 C CD1 . ILE D 2 67  ? -43.779 7.86    23.765  1   33.86  ? 63  ILE C CD1 1 
ATOM   7210 N N   . VAL D 2 68  ? -39.237 11.538  24.349  1   34.23  ? 64  VAL C N   1 
ATOM   7211 C CA  . VAL D 2 68  ? -37.798 11.764  24.344  1   33.51  ? 64  VAL C CA  1 
ATOM   7212 C C   . VAL D 2 68  ? -37.072 10.462  24.01   1   35.24  ? 64  VAL C C   1 
ATOM   7213 O O   . VAL D 2 68  ? -37.497 9.367   24.411  1   33.76  ? 64  VAL C O   1 
ATOM   7214 C CB  . VAL D 2 68  ? -37.309 12.359  25.677  1   30.98  ? 64  VAL C CB  1 
ATOM   7215 C CG1 . VAL D 2 68  ? -37.387 11.35   26.814  1   30.07  ? 64  VAL C CG1 1 
ATOM   7216 C CG2 . VAL D 2 68  ? -35.9   12.908  25.559  1   30.35  ? 64  VAL C CG2 1 
ATOM   7217 N N   . LYS D 2 69  ? -35.966 10.617  23.272  1   37.5   ? 65  LYS C N   1 
ATOM   7218 C CA  . LYS D 2 69  ? -35.244 9.486   22.719  1   40.63  ? 65  LYS C CA  1 
ATOM   7219 C C   . LYS D 2 69  ? -34.065 9.129   23.61   1   40.31  ? 65  LYS C C   1 
ATOM   7220 O O   . LYS D 2 69  ? -33.099 9.873   23.725  1   40.33  ? 65  LYS C O   1 
ATOM   7221 C CB  . LYS D 2 69  ? -34.775 9.701   21.278  1   44.8   ? 65  LYS C CB  1 
ATOM   7222 C CG  . LYS D 2 69  ? -34.453 8.387   20.564  1   56.37  ? 65  LYS C CG  1 
ATOM   7223 C CD  . LYS D 2 69  ? -34.622 8.43    19.039  1   69.52  ? 65  LYS C CD  1 
ATOM   7224 C CE  . LYS D 2 69  ? -35.859 9.195   18.61   1   70.33  ? 65  LYS C CE  1 
ATOM   7225 N NZ  . LYS D 2 69  ? -36.311 9.141   17.222  1   67.9   ? 65  LYS C NZ  1 
ATOM   7226 N N   . LEU D 2 70  ? -34.173 7.966   24.247  1   40.82  ? 66  LEU C N   1 
ATOM   7227 C CA  . LEU D 2 70  ? -32.999 7.294   24.768  1   39.05  ? 66  LEU C CA  1 
ATOM   7228 C C   . LEU D 2 70  ? -32.189 6.823   23.559  1   37.3   ? 66  LEU C C   1 
ATOM   7229 O O   . LEU D 2 70  ? -32.775 6.359   22.587  1   36.82  ? 66  LEU C O   1 
ATOM   7230 C CB  . LEU D 2 70  ? -33.458 6.151   25.672  1   36.43  ? 66  LEU C CB  1 
ATOM   7231 C CG  . LEU D 2 70  ? -32.353 5.412   26.423  1   36.74  ? 66  LEU C CG  1 
ATOM   7232 C CD1 . LEU D 2 70  ? -31.63  6.349   27.367  1   38.41  ? 66  LEU C CD1 1 
ATOM   7233 C CD2 . LEU D 2 70  ? -32.971 4.253   27.178  1   37.52  ? 66  LEU C CD2 1 
ATOM   7234 N N   . LEU D 2 71  ? -30.868 7.048   23.615  1   35.7   ? 67  LEU C N   1 
ATOM   7235 C CA  . LEU D 2 71  ? -29.922 6.791   22.539  1   35.92  ? 67  LEU C CA  1 
ATOM   7236 C C   . LEU D 2 71  ? -29.057 5.579   22.889  1   36.9   ? 67  LEU C C   1 
ATOM   7237 O O   . LEU D 2 71  ? -28.976 4.639   22.1    1   37.8   ? 67  LEU C O   1 
ATOM   7238 C CB  . LEU D 2 71  ? -29.049 8.022   22.25   1   35.27  ? 67  LEU C CB  1 
ATOM   7239 C CG  . LEU D 2 71  ? -29.723 9.275   21.673  1   34.26  ? 67  LEU C CG  1 
ATOM   7240 C CD1 . LEU D 2 71  ? -28.7   10.388  21.537  1   35.14  ? 67  LEU C CD1 1 
ATOM   7241 C CD2 . LEU D 2 71  ? -30.388 9.036   20.329  1   33.81  ? 67  LEU C CD2 1 
ATOM   7242 N N   . ASP D 2 72  ? -28.391 5.642   24.059  1   36.63  ? 68  ASP C N   1 
ATOM   7243 C CA  . ASP D 2 72  ? -27.426 4.653   24.514  1   36.15  ? 68  ASP C CA  1 
ATOM   7244 C C   . ASP D 2 72  ? -27.502 4.569   26.031  1   36.27  ? 68  ASP C C   1 
ATOM   7245 O O   . ASP D 2 72  ? -28.047 5.467   26.674  1   36.78  ? 68  ASP C O   1 
ATOM   7246 C CB  . ASP D 2 72  ? -26.023 4.961   24.029  1   37.87  ? 68  ASP C CB  1 
ATOM   7247 C CG  . ASP D 2 72  ? -25.043 3.8     23.999  1   40.91  ? 68  ASP C CG  1 
ATOM   7248 O OD1 . ASP D 2 72  ? -25.367 2.722   24.54   1   40.66  ? 68  ASP C OD1 1 
ATOM   7249 O OD2 . ASP D 2 72  ? -23.98  3.977   23.379  1   45.16  ? 68  ASP C OD2 1 
ATOM   7250 N N   . VAL D 2 73  ? -27.011 3.45    26.58   1   37.08  ? 69  VAL C N   1 
ATOM   7251 C CA  . VAL D 2 73  ? -26.89  3.256   28.015  1   37.64  ? 69  VAL C CA  1 
ATOM   7252 C C   . VAL D 2 73  ? -25.49  2.727   28.241  1   40.19  ? 69  VAL C C   1 
ATOM   7253 O O   . VAL D 2 73  ? -25.201 1.64    27.759  1   42.62  ? 69  VAL C O   1 
ATOM   7254 C CB  . VAL D 2 73  ? -27.895 2.239   28.583  1   37.21  ? 69  VAL C CB  1 
ATOM   7255 C CG1 . VAL D 2 73  ? -27.578 1.883   30.032  1   37.43  ? 69  VAL C CG1 1 
ATOM   7256 C CG2 . VAL D 2 73  ? -29.334 2.717   28.466  1   36.06  ? 69  VAL C CG2 1 
ATOM   7257 N N   . ILE D 2 74  ? -24.663 3.487   28.976  1   41.63  ? 70  ILE C N   1 
ATOM   7258 C CA  . ILE D 2 74  ? -23.268 3.142   29.204  1   42.83  ? 70  ILE C CA  1 
ATOM   7259 C C   . ILE D 2 74  ? -23.151 2.615   30.625  1   43.74  ? 70  ILE C C   1 
ATOM   7260 O O   . ILE D 2 74  ? -23.449 3.327   31.569  1   43.24  ? 70  ILE C O   1 
ATOM   7261 C CB  . ILE D 2 74  ? -22.337 4.352   29.004  1   42.95  ? 70  ILE C CB  1 
ATOM   7262 C CG1 . ILE D 2 74  ? -22.694 5.215   27.751  1   41.99  ? 70  ILE C CG1 1 
ATOM   7263 C CG2 . ILE D 2 74  ? -20.871 3.904   29.042  1   43.38  ? 70  ILE C CG2 1 
ATOM   7264 C CD1 . ILE D 2 74  ? -21.988 4.847   26.461  1   41.69  ? 70  ILE C CD1 1 
ATOM   7265 N N   . HIS D 2 75  ? -22.744 1.353   30.759  1   47.73  ? 71  HIS C N   1 
ATOM   7266 C CA  . HIS D 2 75  ? -22.552 0.741   32.063  1   51.91  ? 71  HIS C CA  1 
ATOM   7267 C C   . HIS D 2 75  ? -21.086 0.887   32.46   1   54.16  ? 71  HIS C C   1 
ATOM   7268 O O   . HIS D 2 75  ? -20.192 0.793   31.626  1   58.07  ? 71  HIS C O   1 
ATOM   7269 C CB  . HIS D 2 75  ? -22.799 -0.777  32.038  1   56.7   ? 71  HIS C CB  1 
ATOM   7270 C CG  . HIS D 2 75  ? -24.189 -1.227  31.738  1   59.42  ? 71  HIS C CG  1 
ATOM   7271 N ND1 . HIS D 2 75  ? -24.754 -1.074  30.491  1   58.45  ? 71  HIS C ND1 1 
ATOM   7272 C CD2 . HIS D 2 75  ? -25.118 -1.832  32.496  1   62.98  ? 71  HIS C CD2 1 
ATOM   7273 C CE1 . HIS D 2 75  ? -25.986 -1.565  30.504  1   60.65  ? 71  HIS C CE1 1 
ATOM   7274 N NE2 . HIS D 2 75  ? -26.226 -2.04   31.709  1   63.14  ? 71  HIS C NE2 1 
ATOM   7275 N N   . THR D 2 76  ? -20.852 1.125   33.746  1   52.55  ? 72  THR C N   1 
ATOM   7276 C CA  . THR D 2 76  ? -19.558 0.87    34.339  1   53.6   ? 72  THR C CA  1 
ATOM   7277 C C   . THR D 2 76  ? -19.883 -0.014  35.547  1   53.7   ? 72  THR C C   1 
ATOM   7278 O O   . THR D 2 76  ? -21.041 -0.435  35.668  1   49.13  ? 72  THR C O   1 
ATOM   7279 C CB  . THR D 2 76  ? -18.796 2.197   34.545  1   55.43  ? 72  THR C CB  1 
ATOM   7280 O OG1 . THR D 2 76  ? -19.036 2.855   35.788  1   58.25  ? 72  THR C OG1 1 
ATOM   7281 C CG2 . THR D 2 76  ? -19.049 3.236   33.454  1   50.51  ? 72  THR C CG2 1 
ATOM   7282 N N   . GLU D 2 77  ? -18.879 -0.363  36.372  1   58.82  ? 73  GLU C N   1 
ATOM   7283 C CA  . GLU D 2 77  ? -19.09  -1.197  37.551  1   58.88  ? 73  GLU C CA  1 
ATOM   7284 C C   . GLU D 2 77  ? -19.801 -0.399  38.649  1   58.1   ? 73  GLU C C   1 
ATOM   7285 O O   . GLU D 2 77  ? -20.509 -0.976  39.469  1   56.73  ? 73  GLU C O   1 
ATOM   7286 C CB  . GLU D 2 77  ? -17.772 -1.802  38.029  1   64.28  ? 73  GLU C CB  1 
ATOM   7287 C CG  . GLU D 2 77  ? -17.948 -2.962  39.007  1   72.73  ? 73  GLU C CG  1 
ATOM   7288 C CD  . GLU D 2 77  ? -16.683 -3.533  39.654  1   80.87  ? 73  GLU C CD  1 
ATOM   7289 O OE1 . GLU D 2 77  ? -15.695 -3.78   38.927  1   81.31  ? 73  GLU C OE1 1 
ATOM   7290 O OE2 . GLU D 2 77  ? -16.665 -3.745  40.889  1   82.66  ? 73  GLU C OE2 1 
ATOM   7291 N N   . ASN D 2 78  ? -19.647 0.938   38.63   1   59.58  ? 74  ASN C N   1 
ATOM   7292 C CA  . ASN D 2 78  ? -20.072 1.821   39.709  1   56.43  ? 74  ASN C CA  1 
ATOM   7293 C C   . ASN D 2 78  ? -20.992 2.939   39.221  1   53.22  ? 74  ASN C C   1 
ATOM   7294 O O   . ASN D 2 78  ? -21.652 3.56    40.039  1   55.49  ? 74  ASN C O   1 
ATOM   7295 C CB  . ASN D 2 78  ? -18.865 2.353   40.477  1   58.9   ? 74  ASN C CB  1 
ATOM   7296 C CG  . ASN D 2 78  ? -18.043 1.234   41.087  1   63.78  ? 74  ASN C CG  1 
ATOM   7297 O OD1 . ASN D 2 78  ? -18.323 0.785   42.21   1   65.26  ? 74  ASN C OD1 1 
ATOM   7298 N ND2 . ASN D 2 78  ? -17.024 0.769   40.372  1   64.1   ? 74  ASN C ND2 1 
ATOM   7299 N N   . LYS D 2 79  ? -21.043 3.212   37.914  1   52.34  ? 75  LYS C N   1 
ATOM   7300 C CA  . LYS D 2 79  ? -21.908 4.262   37.383  1   52.83  ? 75  LYS C CA  1 
ATOM   7301 C C   . LYS D 2 79  ? -22.819 3.693   36.292  1   49.95  ? 75  LYS C C   1 
ATOM   7302 O O   . LYS D 2 79  ? -22.514 2.672   35.698  1   53.34  ? 75  LYS C O   1 
ATOM   7303 C CB  . LYS D 2 79  ? -21.029 5.354   36.761  1   59.95  ? 75  LYS C CB  1 
ATOM   7304 C CG  . LYS D 2 79  ? -20.214 6.221   37.708  1   66.81  ? 75  LYS C CG  1 
ATOM   7305 C CD  . LYS D 2 79  ? -21.04  7.318   38.38   1   69.03  ? 75  LYS C CD  1 
ATOM   7306 C CE  . LYS D 2 79  ? -20.264 8.081   39.421  1   75.71  ? 75  LYS C CE  1 
ATOM   7307 N NZ  . LYS D 2 79  ? -18.899 8.379   38.968  1   81.79  ? 75  LYS C NZ  1 
ATOM   7308 N N   . LEU D 2 80  ? -23.944 4.357   36.009  1   45.51  ? 76  LEU C N   1 
ATOM   7309 C CA  . LEU D 2 80  ? -24.758 4.046   34.836  1   42.9   ? 76  LEU C CA  1 
ATOM   7310 C C   . LEU D 2 80  ? -25.133 5.349   34.118  1   43.08  ? 76  LEU C C   1 
ATOM   7311 O O   . LEU D 2 80  ? -25.619 6.277   34.76   1   45.38  ? 76  LEU C O   1 
ATOM   7312 C CB  . LEU D 2 80  ? -25.991 3.333   35.392  1   39.66  ? 76  LEU C CB  1 
ATOM   7313 C CG  . LEU D 2 80  ? -26.853 2.53    34.411  1   36.86  ? 76  LEU C CG  1 
ATOM   7314 C CD1 . LEU D 2 80  ? -26.164 1.23    33.992  1   38.88  ? 76  LEU C CD1 1 
ATOM   7315 C CD2 . LEU D 2 80  ? -28.183 2.235   35.08   1   34.81  ? 76  LEU C CD2 1 
ATOM   7316 N N   . TYR D 2 81  ? -24.895 5.467   32.803  1   42.61  ? 77  TYR C N   1 
ATOM   7317 C CA  . TYR D 2 81  ? -25.179 6.739   32.132  1   41.66  ? 77  TYR C CA  1 
ATOM   7318 C C   . TYR D 2 81  ? -26.221 6.578   31.03   1   39.36  ? 77  TYR C C   1 
ATOM   7319 O O   . TYR D 2 81  ? -26.01  5.817   30.086  1   39.97  ? 77  TYR C O   1 
ATOM   7320 C CB  . TYR D 2 81  ? -23.961 7.338   31.438  1   43.05  ? 77  TYR C CB  1 
ATOM   7321 C CG  . TYR D 2 81  ? -22.871 7.796   32.384  1   45.32  ? 77  TYR C CG  1 
ATOM   7322 C CD1 . TYR D 2 81  ? -21.908 6.902   32.816  1   48.82  ? 77  TYR C CD1 1 
ATOM   7323 C CD2 . TYR D 2 81  ? -22.787 9.109   32.817  1   44.9   ? 77  TYR C CD2 1 
ATOM   7324 C CE1 . TYR D 2 81  ? -20.885 7.298   33.657  1   52.15  ? 77  TYR C CE1 1 
ATOM   7325 C CE2 . TYR D 2 81  ? -21.762 9.52    33.654  1   48.65  ? 77  TYR C CE2 1 
ATOM   7326 C CZ  . TYR D 2 81  ? -20.807 8.61    34.08   1   52.24  ? 77  TYR C CZ  1 
ATOM   7327 O OH  . TYR D 2 81  ? -19.758 8.927   34.907  1   57.55  ? 77  TYR C OH  1 
ATOM   7328 N N   . LEU D 2 82  ? -27.32  7.33    31.139  1   36.82  ? 78  LEU C N   1 
ATOM   7329 C CA  . LEU D 2 82  ? -28.33  7.301   30.094  1   37.64  ? 78  LEU C CA  1 
ATOM   7330 C C   . LEU D 2 82  ? -28.026 8.457   29.144  1   36.9   ? 78  LEU C C   1 
ATOM   7331 O O   . LEU D 2 82  ? -27.854 9.588   29.592  1   36.31  ? 78  LEU C O   1 
ATOM   7332 C CB  . LEU D 2 82  ? -29.753 7.395   30.655  1   39.07  ? 78  LEU C CB  1 
ATOM   7333 C CG  . LEU D 2 82  ? -30.108 6.547   31.888  1   39.93  ? 78  LEU C CG  1 
ATOM   7334 C CD1 . LEU D 2 82  ? -31.62  6.474   32.049  1   38.92  ? 78  LEU C CD1 1 
ATOM   7335 C CD2 . LEU D 2 82  ? -29.533 5.157   31.821  1   44.3   ? 78  LEU C CD2 1 
ATOM   7336 N N   . VAL D 2 83  ? -27.923 8.151   27.846  1   34.78  ? 79  VAL C N   1 
ATOM   7337 C CA  . VAL D 2 83  ? -27.628 9.141   26.832  1   33.78  ? 79  VAL C CA  1 
ATOM   7338 C C   . VAL D 2 83  ? -28.931 9.48    26.116  1   33.85  ? 79  VAL C C   1 
ATOM   7339 O O   . VAL D 2 83  ? -29.403 8.692   25.304  1   34.09  ? 79  VAL C O   1 
ATOM   7340 C CB  . VAL D 2 83  ? -26.586 8.582   25.847  1   33.18  ? 79  VAL C CB  1 
ATOM   7341 C CG1 . VAL D 2 83  ? -26.163 9.634   24.83   1   33.31  ? 79  VAL C CG1 1 
ATOM   7342 C CG2 . VAL D 2 83  ? -25.385 8.025   26.586  1   33.59  ? 79  VAL C CG2 1 
ATOM   7343 N N   . PHE D 2 84  ? -29.501 10.653  26.421  1   33.33  ? 80  PHE C N   1 
ATOM   7344 C CA  . PHE D 2 84  ? -30.724 11.116  25.775  1   33.61  ? 80  PHE C CA  1 
ATOM   7345 C C   . PHE D 2 84  ? -30.396 12.051  24.608  1   34.27  ? 80  PHE C C   1 
ATOM   7346 O O   . PHE D 2 84  ? -29.302 12.596  24.52   1   36.52  ? 80  PHE C O   1 
ATOM   7347 C CB  . PHE D 2 84  ? -31.622 11.855  26.773  1   32.62  ? 80  PHE C CB  1 
ATOM   7348 C CG  . PHE D 2 84  ? -32.269 10.968  27.821  1   31.49  ? 80  PHE C CG  1 
ATOM   7349 C CD1 . PHE D 2 84  ? -33.418 10.249  27.527  1   31.02  ? 80  PHE C CD1 1 
ATOM   7350 C CD2 . PHE D 2 84  ? -31.718 10.845  29.088  1   32.1   ? 80  PHE C CD2 1 
ATOM   7351 C CE1 . PHE D 2 84  ? -34.005 9.434   28.479  1   31.11  ? 80  PHE C CE1 1 
ATOM   7352 C CE2 . PHE D 2 84  ? -32.301 10.021  30.034  1   32.33  ? 80  PHE C CE2 1 
ATOM   7353 C CZ  . PHE D 2 84  ? -33.44  9.31    29.727  1   31.79  ? 80  PHE C CZ  1 
ATOM   7354 N N   . GLU D 2 85  ? -31.357 12.234  23.704  1   33.37  ? 81  GLU C N   1 
ATOM   7355 C CA  . GLU D 2 85  ? -31.281 13.32   22.751  1   34.73  ? 81  GLU C CA  1 
ATOM   7356 C C   . GLU D 2 85  ? -31.441 14.62   23.543  1   36.29  ? 81  GLU C C   1 
ATOM   7357 O O   . GLU D 2 85  ? -32.172 14.661  24.527  1   36.97  ? 81  GLU C O   1 
ATOM   7358 C CB  . GLU D 2 85  ? -32.39  13.182  21.71   1   34.11  ? 81  GLU C CB  1 
ATOM   7359 C CG  . GLU D 2 85  ? -33.762 13.623  22.22   1   34.32  ? 81  GLU C CG  1 
ATOM   7360 C CD  . GLU D 2 85  ? -34.903 13.48   21.229  1   37.31  ? 81  GLU C CD  1 
ATOM   7361 O OE1 . GLU D 2 85  ? -34.825 14.111  20.146  1   38.81  ? 81  GLU C OE1 1 
ATOM   7362 O OE2 . GLU D 2 85  ? -35.87  12.74   21.526  1   37.79  ? 81  GLU C OE2 1 
ATOM   7363 N N   . PHE D 2 86  ? -30.758 15.685  23.114  1   37.5   ? 82  PHE C N   1 
ATOM   7364 C CA  . PHE D 2 86  ? -30.811 16.949  23.826  1   36.91  ? 82  PHE C CA  1 
ATOM   7365 C C   . PHE D 2 86  ? -31.944 17.802  23.272  1   38.48  ? 82  PHE C C   1 
ATOM   7366 O O   . PHE D 2 86  ? -31.993 17.987  22.066  1   42.3   ? 82  PHE C O   1 
ATOM   7367 C CB  . PHE D 2 86  ? -29.492 17.688  23.635  1   36.18  ? 82  PHE C CB  1 
ATOM   7368 C CG  . PHE D 2 86  ? -29.549 19.066  24.253  1   36.66  ? 82  PHE C CG  1 
ATOM   7369 C CD1 . PHE D 2 86  ? -29.497 19.211  25.639  1   36.25  ? 82  PHE C CD1 1 
ATOM   7370 C CD2 . PHE D 2 86  ? -29.694 20.203  23.455  1   36.65  ? 82  PHE C CD2 1 
ATOM   7371 C CE1 . PHE D 2 86  ? -29.568 20.475  26.219  1   35.48  ? 82  PHE C CE1 1 
ATOM   7372 C CE2 . PHE D 2 86  ? -29.745 21.462  24.037  1   36     ? 82  PHE C CE2 1 
ATOM   7373 C CZ  . PHE D 2 86  ? -29.688 21.591  25.41   1   35.87  ? 82  PHE C CZ  1 
ATOM   7374 N N   . LEU D 2 87  ? -32.831 18.301  24.152  1   38.87  ? 83  LEU C N   1 
ATOM   7375 C CA  . LEU D 2 87  ? -33.853 19.283  23.801  1   38.99  ? 83  LEU C CA  1 
ATOM   7376 C C   . LEU D 2 87  ? -33.621 20.59   24.556  1   41.01  ? 83  LEU C C   1 
ATOM   7377 O O   . LEU D 2 87  ? -33.12  20.578  25.673  1   43.75  ? 83  LEU C O   1 
ATOM   7378 C CB  . LEU D 2 87  ? -35.256 18.724  23.986  1   37.1   ? 83  LEU C CB  1 
ATOM   7379 C CG  . LEU D 2 87  ? -35.705 17.775  22.871  1   37.53  ? 83  LEU C CG  1 
ATOM   7380 C CD1 . LEU D 2 87  ? -35.632 16.327  23.319  1   39.5   ? 83  LEU C CD1 1 
ATOM   7381 C CD2 . LEU D 2 87  ? -37.086 18.09   22.401  1   36.14  ? 83  LEU C CD2 1 
ATOM   7382 N N   . HIS D 2 88  ? -33.958 21.714  23.917  1   43.04  ? 84  HIS C N   1 
ATOM   7383 C CA  . HIS D 2 88  ? -33.447 23.035  24.26   1   46.16  ? 84  HIS C CA  1 
ATOM   7384 C C   . HIS D 2 88  ? -33.779 23.45   25.694  1   43.98  ? 84  HIS C C   1 
ATOM   7385 O O   . HIS D 2 88  ? -32.966 24.123  26.33   1   42.78  ? 84  HIS C O   1 
ATOM   7386 C CB  . HIS D 2 88  ? -33.917 24.075  23.228  1   53.55  ? 84  HIS C CB  1 
ATOM   7387 C CG  . HIS D 2 88  ? -33.694 25.5    23.655  1   64.81  ? 84  HIS C CG  1 
ATOM   7388 N ND1 . HIS D 2 88  ? -34.702 26.385  23.991  1   67.35  ? 84  HIS C ND1 1 
ATOM   7389 C CD2 . HIS D 2 88  ? -32.547 26.188  23.796  1   67.77  ? 84  HIS C CD2 1 
ATOM   7390 C CE1 . HIS D 2 88  ? -34.174 27.557  24.321  1   68.79  ? 84  HIS C CE1 1 
ATOM   7391 N NE2 . HIS D 2 88  ? -32.869 27.461  24.209  1   70.73  ? 84  HIS C NE2 1 
ATOM   7392 N N   . GLN D 2 89  ? -34.994 23.103  26.153  1   42.36  ? 85  GLN C N   1 
ATOM   7393 C CA  . GLN D 2 89  ? -35.487 23.454  27.475  1   42.6   ? 85  GLN C CA  1 
ATOM   7394 C C   . GLN D 2 89  ? -36.836 22.798  27.748  1   40.65  ? 85  GLN C C   1 
ATOM   7395 O O   . GLN D 2 89  ? -37.362 22.101  26.881  1   38.32  ? 85  GLN C O   1 
ATOM   7396 C CB  . GLN D 2 89  ? -35.575 24.972  27.626  1   46.63  ? 85  GLN C CB  1 
ATOM   7397 C CG  . GLN D 2 89  ? -36.664 25.698  26.844  1   44.53  ? 85  GLN C CG  1 
ATOM   7398 C CD  . GLN D 2 89  ? -36.628 27.139  27.297  1   49.09  ? 85  GLN C CD  1 
ATOM   7399 O OE1 . GLN D 2 89  ? -35.949 27.435  28.29   1   52.5   ? 85  GLN C OE1 1 
ATOM   7400 N NE2 . GLN D 2 89  ? -37.33  28.042  26.622  1   50.71  ? 85  GLN C NE2 1 
ATOM   7401 N N   . ASP D 2 90  ? -37.386 23.044  28.956  1   39.11  ? 86  ASP C N   1 
ATOM   7402 C CA  . ASP D 2 90  ? -38.622 22.408  29.399  1   37.09  ? 86  ASP C CA  1 
ATOM   7403 C C   . ASP D 2 90  ? -39.78  23.411  29.34   1   37.71  ? 86  ASP C C   1 
ATOM   7404 O O   . ASP D 2 90  ? -39.554 24.627  29.415  1   39.84  ? 86  ASP C O   1 
ATOM   7405 C CB  . ASP D 2 90  ? -38.451 21.794  30.776  1   35.33  ? 86  ASP C CB  1 
ATOM   7406 C CG  . ASP D 2 90  ? -38.261 22.817  31.882  1   38.28  ? 86  ASP C CG  1 
ATOM   7407 O OD1 . ASP D 2 90  ? -39.23  23.536  32.2    1   41.6   ? 86  ASP C OD1 1 
ATOM   7408 O OD2 . ASP D 2 90  ? -37.136 22.931  32.388  1   40.4   ? 86  ASP C OD2 1 
ATOM   7409 N N   . LEU D 2 91  ? -41.017 22.883  29.262  1   33.7   ? 87  LEU C N   1 
ATOM   7410 C CA  . LEU D 2 91  ? -42.227 23.682  29.14   1   33.6   ? 87  LEU C CA  1 
ATOM   7411 C C   . LEU D 2 91  ? -42.329 24.729  30.247  1   34.41  ? 87  LEU C C   1 
ATOM   7412 O O   . LEU D 2 91  ? -42.9   25.796  30.03   1   35.36  ? 87  LEU C O   1 
ATOM   7413 C CB  . LEU D 2 91  ? -43.48  22.816  29.141  1   32.48  ? 87  LEU C CB  1 
ATOM   7414 C CG  . LEU D 2 91  ? -44.766 23.539  28.719  1   33.05  ? 87  LEU C CG  1 
ATOM   7415 C CD1 . LEU D 2 91  ? -44.615 24.056  27.3    1   33.7   ? 87  LEU C CD1 1 
ATOM   7416 C CD2 . LEU D 2 91  ? -45.967 22.615  28.793  1   31.52  ? 87  LEU C CD2 1 
ATOM   7417 N N   . LYS D 2 92  ? -41.819 24.395  31.435  1   33.63  ? 88  LYS C N   1 
ATOM   7418 C CA  . LYS D 2 92  ? -41.938 25.272  32.582  1   34.15  ? 88  LYS C CA  1 
ATOM   7419 C C   . LYS D 2 92  ? -41.144 26.543  32.312  1   35.94  ? 88  LYS C C   1 
ATOM   7420 O O   . LYS D 2 92  ? -41.664 27.643  32.516  1   35.97  ? 88  LYS C O   1 
ATOM   7421 C CB  . LYS D 2 92  ? -41.536 24.575  33.888  1   33.28  ? 88  LYS C CB  1 
ATOM   7422 C CG  . LYS D 2 92  ? -41.308 25.498  35.074  1   35.82  ? 88  LYS C CG  1 
ATOM   7423 C CD  . LYS D 2 92  ? -42.367 26.561  35.353  1   38.72  ? 88  LYS C CD  1 
ATOM   7424 C CE  . LYS D 2 92  ? -43.725 25.961  35.556  1   41.16  ? 88  LYS C CE  1 
ATOM   7425 N NZ  . LYS D 2 92  ? -44.709 26.9    36.127  1   42.76  ? 88  LYS C NZ  1 
ATOM   7426 N N   . LYS D 2 93  ? -39.891 26.36   31.87   1   34.83  ? 89  LYS C N   1 
ATOM   7427 C CA  . LYS D 2 93  ? -38.99  27.477  31.67   1   36.35  ? 89  LYS C CA  1 
ATOM   7428 C C   . LYS D 2 93  ? -39.53  28.38   30.578  1   36.76  ? 89  LYS C C   1 
ATOM   7429 O O   . LYS D 2 93  ? -39.469 29.601  30.709  1   36.09  ? 89  LYS C O   1 
ATOM   7430 C CB  . LYS D 2 93  ? -37.593 26.988  31.3    1   37.78  ? 89  LYS C CB  1 
ATOM   7431 C CG  . LYS D 2 93  ? -36.801 26.451  32.488  1   39.85  ? 89  LYS C CG  1 
ATOM   7432 C CD  . LYS D 2 93  ? -35.34  26.265  32.078  1   44.67  ? 89  LYS C CD  1 
ATOM   7433 C CE  . LYS D 2 93  ? -34.343 26.266  33.211  1   44.4   ? 89  LYS C CE  1 
ATOM   7434 N NZ  . LYS D 2 93  ? -34.975 25.579  34.338  1   44.77  ? 89  LYS C NZ  1 
ATOM   7435 N N   . PHE D 2 94  ? -40.083 27.74   29.536  1   37.13  ? 90  PHE C N   1 
ATOM   7436 C CA  . PHE D 2 94  ? -40.666 28.432  28.394  1   39.53  ? 90  PHE C CA  1 
ATOM   7437 C C   . PHE D 2 94  ? -41.881 29.244  28.834  1   40.8   ? 90  PHE C C   1 
ATOM   7438 O O   . PHE D 2 94  ? -42.038 30.393  28.423  1   42.01  ? 90  PHE C O   1 
ATOM   7439 C CB  . PHE D 2 94  ? -41.089 27.433  27.315  1   39.22  ? 90  PHE C CB  1 
ATOM   7440 C CG  . PHE D 2 94  ? -41.795 28.054  26.114  1   39.44  ? 90  PHE C CG  1 
ATOM   7441 C CD1 . PHE D 2 94  ? -41.114 28.894  25.242  1   40.49  ? 90  PHE C CD1 1 
ATOM   7442 C CD2 . PHE D 2 94  ? -43.131 27.77   25.84   1   38.35  ? 90  PHE C CD2 1 
ATOM   7443 C CE1 . PHE D 2 94  ? -41.769 29.435  24.142  1   41.5   ? 90  PHE C CE1 1 
ATOM   7444 C CE2 . PHE D 2 94  ? -43.775 28.32   24.743  1   38.53  ? 90  PHE C CE2 1 
ATOM   7445 C CZ  . PHE D 2 94  ? -43.094 29.147  23.893  1   40.11  ? 90  PHE C CZ  1 
ATOM   7446 N N   . MET D 2 95  ? -42.735 28.618  29.657  1   39.75  ? 91  MET C N   1 
ATOM   7447 C CA  . MET D 2 95  ? -43.9   29.275  30.228  1   38.69  ? 91  MET C CA  1 
ATOM   7448 C C   . MET D 2 95  ? -43.488 30.493  31.046  1   37.97  ? 91  MET C C   1 
ATOM   7449 O O   . MET D 2 95  ? -44.162 31.501  30.966  1   40.26  ? 91  MET C O   1 
ATOM   7450 C CB  . MET D 2 95  ? -44.761 28.31   31.047  1   38.24  ? 91  MET C CB  1 
ATOM   7451 C CG  . MET D 2 95  ? -45.859 27.666  30.23   1   41.21  ? 91  MET C CG  1 
ATOM   7452 S SD  . MET D 2 95  ? -46.715 26.264  30.987  1   47     ? 91  MET C SD  1 
ATOM   7453 C CE  . MET D 2 95  ? -45.562 25.637  32.217  1   42.55  ? 91  MET C CE  1 
ATOM   7454 N N   . ASP D 2 96  ? -42.378 30.417  31.787  1   36.8   ? 92  ASP C N   1 
ATOM   7455 C CA  . ASP D 2 96  ? -41.931 31.523  32.625  1   38.24  ? 92  ASP C CA  1 
ATOM   7456 C C   . ASP D 2 96  ? -41.358 32.639  31.764  1   39.43  ? 92  ASP C C   1 
ATOM   7457 O O   . ASP D 2 96  ? -41.604 33.804  32.042  1   40.74  ? 92  ASP C O   1 
ATOM   7458 C CB  . ASP D 2 96  ? -40.997 31.108  33.751  1   37.29  ? 92  ASP C CB  1 
ATOM   7459 C CG  . ASP D 2 96  ? -41.636 30.219  34.804  1   37.7   ? 92  ASP C CG  1 
ATOM   7460 O OD1 . ASP D 2 96  ? -42.867 30.214  34.909  1   37.66  ? 92  ASP C OD1 1 
ATOM   7461 O OD2 . ASP D 2 96  ? -40.906 29.488  35.488  1   39.86  ? 92  ASP C OD2 1 
ATOM   7462 N N   . ALA D 2 97  ? -40.6   32.287  30.723  1   39.24  ? 93  ALA C N   1 
ATOM   7463 C CA  . ALA D 2 97  ? -40.118 33.307  29.806  1   40.21  ? 93  ALA C CA  1 
ATOM   7464 C C   . ALA D 2 97  ? -41.315 33.95   29.111  1   41.74  ? 93  ALA C C   1 
ATOM   7465 O O   . ALA D 2 97  ? -41.253 35.129  28.759  1   44.86  ? 93  ALA C O   1 
ATOM   7466 C CB  . ALA D 2 97  ? -39.137 32.72   28.822  1   38.98  ? 93  ALA C CB  1 
ATOM   7467 N N   . SER D 2 98  ? -42.416 33.191  28.979  1   40.68  ? 94  SER C N   1 
ATOM   7468 C CA  . SER D 2 98  ? -43.614 33.619  28.27   1   41.95  ? 94  SER C CA  1 
ATOM   7469 C C   . SER D 2 98  ? -44.637 34.252  29.214  1   44.42  ? 94  SER C C   1 
ATOM   7470 O O   . SER D 2 98  ? -45.763 34.527  28.809  1   46.62  ? 94  SER C O   1 
ATOM   7471 C CB  . SER D 2 98  ? -44.23  32.474  27.492  1   40.03  ? 94  SER C CB  1 
ATOM   7472 O OG  . SER D 2 98  ? -43.582 32.3    26.24   1   40.78  ? 94  SER C OG  1 
ATOM   7473 N N   . ALA D 2 99  ? -44.241 34.529  30.459  1   44.85  ? 95  ALA C N   1 
ATOM   7474 C CA  . ALA D 2 99  ? -45.166 35.05   31.451  1   45.64  ? 95  ALA C CA  1 
ATOM   7475 C C   . ALA D 2 99  ? -45.789 36.392  31.029  1   47.31  ? 95  ALA C C   1 
ATOM   7476 O O   . ALA D 2 99  ? -46.982 36.611  31.228  1   48.29  ? 95  ALA C O   1 
ATOM   7477 C CB  . ALA D 2 99  ? -44.486 35.115  32.803  1   46.55  ? 95  ALA C CB  1 
ATOM   7478 N N   . LEU D 2 100 ? -45.002 37.31   30.467  1   47.15  ? 96  LEU C N   1 
ATOM   7479 C CA  . LEU D 2 100 ? -45.575 38.603  30.128  1   49.29  ? 96  LEU C CA  1 
ATOM   7480 C C   . LEU D 2 100 ? -46.102 38.618  28.689  1   51.73  ? 96  LEU C C   1 
ATOM   7481 O O   . LEU D 2 100 ? -47.142 39.228  28.445  1   53.62  ? 96  LEU C O   1 
ATOM   7482 C CB  . LEU D 2 100 ? -44.628 39.761  30.433  1   47.88  ? 96  LEU C CB  1 
ATOM   7483 C CG  . LEU D 2 100 ? -44.008 39.714  31.828  1   46.03  ? 96  LEU C CG  1 
ATOM   7484 C CD1 . LEU D 2 100 ? -43.055 40.837  32.09   1   47.54  ? 96  LEU C CD1 1 
ATOM   7485 C CD2 . LEU D 2 100 ? -45.059 39.661  32.895  1   45.21  ? 96  LEU C CD2 1 
ATOM   7486 N N   . THR D 2 101 ? -45.398 37.971  27.74   1   51.49  ? 97  THR C N   1 
ATOM   7487 C CA  . THR D 2 101 ? -45.775 38.073  26.33   1   52.02  ? 97  THR C CA  1 
ATOM   7488 C C   . THR D 2 101 ? -47.027 37.254  26.061  1   49.87  ? 97  THR C C   1 
ATOM   7489 O O   . THR D 2 101 ? -47.884 37.694  25.312  1   51.15  ? 97  THR C O   1 
ATOM   7490 C CB  . THR D 2 101 ? -44.688 37.668  25.329  1   52.9   ? 97  THR C CB  1 
ATOM   7491 O OG1 . THR D 2 101 ? -44.582 36.243  25.388  1   54.68  ? 97  THR C OG1 1 
ATOM   7492 C CG2 . THR D 2 101 ? -43.369 38.397  25.531  1   52.26  ? 97  THR C CG2 1 
ATOM   7493 N N   . GLY D 2 102 ? -47.105 36.061  26.659  1   47.73  ? 98  GLY C N   1 
ATOM   7494 C CA  . GLY D 2 102 ? -48.115 35.071  26.321  1   46.32  ? 98  GLY C CA  1 
ATOM   7495 C C   . GLY D 2 102 ? -47.546 34.051  25.342  1   46.18  ? 98  GLY C C   1 
ATOM   7496 O O   . GLY D 2 102 ? -46.509 34.304  24.728  1   47.41  ? 98  GLY C O   1 
ATOM   7497 N N   . ILE D 2 103 ? -48.207 32.885  25.246  1   45.41  ? 99  ILE C N   1 
ATOM   7498 C CA  . ILE D 2 103 ? -47.905 31.865  24.247  1   44.05  ? 99  ILE C CA  1 
ATOM   7499 C C   . ILE D 2 103 ? -48.99  31.893  23.172  1   46.41  ? 99  ILE C C   1 
ATOM   7500 O O   . ILE D 2 103 ? -50.171 31.729  23.49   1   47.71  ? 99  ILE C O   1 
ATOM   7501 C CB  . ILE D 2 103 ? -47.846 30.467  24.882  1   42.34  ? 99  ILE C CB  1 
ATOM   7502 C CG1 . ILE D 2 103 ? -46.731 30.345  25.931  1   41.06  ? 99  ILE C CG1 1 
ATOM   7503 C CG2 . ILE D 2 103 ? -47.73  29.397  23.794  1   42.21  ? 99  ILE C CG2 1 
ATOM   7504 C CD1 . ILE D 2 103 ? -46.778 29.044  26.726  1   38.01  ? 99  ILE C CD1 1 
ATOM   7505 N N   . PRO D 2 104 ? -48.635 32.1    21.879  1   47.9   ? 100 PRO C N   1 
ATOM   7506 C CA  . PRO D 2 104 ? -49.608 32.079  20.782  1   50.12  ? 100 PRO C CA  1 
ATOM   7507 C C   . PRO D 2 104 ? -50.51  30.84   20.806  1   54.51  ? 100 PRO C C   1 
ATOM   7508 O O   . PRO D 2 104 ? -50.036 29.705  20.97   1   54.64  ? 100 PRO C O   1 
ATOM   7509 C CB  . PRO D 2 104 ? -48.729 32.094  19.535  1   48.86  ? 100 PRO C CB  1 
ATOM   7510 C CG  . PRO D 2 104 ? -47.428 32.713  19.957  1   47.61  ? 100 PRO C CG  1 
ATOM   7511 C CD  . PRO D 2 104 ? -47.265 32.367  21.417  1   47.94  ? 100 PRO C CD  1 
ATOM   7512 N N   . LEU D 2 105 ? -51.821 31.072  20.631  1   58.84  ? 101 LEU C N   1 
ATOM   7513 C CA  . LEU D 2 105 ? -52.846 30.048  20.787  1   58.71  ? 101 LEU C CA  1 
ATOM   7514 C C   . LEU D 2 105 ? -52.642 28.925  19.767  1   56.95  ? 101 LEU C C   1 
ATOM   7515 O O   . LEU D 2 105 ? -52.943 27.774  20.067  1   54.59  ? 101 LEU C O   1 
ATOM   7516 C CB  . LEU D 2 105 ? -54.23  30.702  20.73   1   62.47  ? 101 LEU C CB  1 
ATOM   7517 C CG  . LEU D 2 105 ? -55.449 29.833  21.055  1   66.16  ? 101 LEU C CG  1 
ATOM   7518 C CD1 . LEU D 2 105 ? -55.897 28.967  19.885  1   66.61  ? 101 LEU C CD1 1 
ATOM   7519 C CD2 . LEU D 2 105 ? -55.18  28.959  22.265  1   68.53  ? 101 LEU C CD2 1 
ATOM   7520 N N   . PRO D 2 106 ? -52.148 29.212  18.534  1   58.56  ? 102 PRO C N   1 
ATOM   7521 C CA  . PRO D 2 106 ? -51.68  28.165  17.617  1   57.74  ? 102 PRO C CA  1 
ATOM   7522 C C   . PRO D 2 106 ? -50.646 27.21   18.208  1   54.43  ? 102 PRO C C   1 
ATOM   7523 O O   . PRO D 2 106 ? -50.717 26.011  17.968  1   55.47  ? 102 PRO C O   1 
ATOM   7524 C CB  . PRO D 2 106 ? -51.068 28.95   16.46   1   58.47  ? 102 PRO C CB  1 
ATOM   7525 C CG  . PRO D 2 106 ? -51.819 30.253  16.477  1   59.33  ? 102 PRO C CG  1 
ATOM   7526 C CD  . PRO D 2 106 ? -52.081 30.55   17.926  1   57.99  ? 102 PRO C CD  1 
ATOM   7527 N N   . LEU D 2 107 ? -49.683 27.746  18.966  1   50.46  ? 103 LEU C N   1 
ATOM   7528 C CA  . LEU D 2 107 ? -48.623 26.921  19.522  1   46.91  ? 103 LEU C CA  1 
ATOM   7529 C C   . LEU D 2 107 ? -49.167 26.032  20.64   1   45.14  ? 103 LEU C C   1 
ATOM   7530 O O   . LEU D 2 107 ? -48.707 24.907  20.823  1   44.11  ? 103 LEU C O   1 
ATOM   7531 C CB  . LEU D 2 107 ? -47.484 27.812  20.007  1   44.99  ? 103 LEU C CB  1 
ATOM   7532 C CG  . LEU D 2 107 ? -46.233 27.088  20.51   1   42.54  ? 103 LEU C CG  1 
ATOM   7533 C CD1 . LEU D 2 107 ? -45.531 26.321  19.398  1   42.71  ? 103 LEU C CD1 1 
ATOM   7534 C CD2 . LEU D 2 107 ? -45.276 28.062  21.163  1   42.11  ? 103 LEU C CD2 1 
ATOM   7535 N N   . ILE D 2 108 ? -50.139 26.554  21.395  1   45.24  ? 104 ILE C N   1 
ATOM   7536 C CA  . ILE D 2 108 ? -50.743 25.819  22.498  1   43.68  ? 104 ILE C CA  1 
ATOM   7537 C C   . ILE D 2 108 ? -51.437 24.576  21.931  1   45.34  ? 104 ILE C C   1 
ATOM   7538 O O   . ILE D 2 108 ? -51.321 23.473  22.463  1   45.16  ? 104 ILE C O   1 
ATOM   7539 C CB  . ILE D 2 108 ? -51.678 26.725  23.332  1   42.23  ? 104 ILE C CB  1 
ATOM   7540 C CG1 . ILE D 2 108 ? -50.961 27.984  23.853  1   42.37  ? 104 ILE C CG1 1 
ATOM   7541 C CG2 . ILE D 2 108 ? -52.344 25.951  24.468  1   39.79  ? 104 ILE C CG2 1 
ATOM   7542 C CD1 . ILE D 2 108 ? -51.75  28.84   24.841  1   42.33  ? 104 ILE C CD1 1 
ATOM   7543 N N   . LYS D 2 109 ? -52.142 24.758  20.816  1   49.05  ? 105 LYS C N   1 
ATOM   7544 C CA  . LYS D 2 109 ? -52.78  23.648  20.14   1   52.5   ? 105 LYS C CA  1 
ATOM   7545 C C   . LYS D 2 109 ? -51.71  22.64   19.724  1   52.09  ? 105 LYS C C   1 
ATOM   7546 O O   . LYS D 2 109 ? -51.837 21.435  19.955  1   50.07  ? 105 LYS C O   1 
ATOM   7547 C CB  . LYS D 2 109 ? -53.485 24.167  18.883  1   58.6   ? 105 LYS C CB  1 
ATOM   7548 C CG  . LYS D 2 109 ? -54.898 24.665  19.056  1   63.37  ? 105 LYS C CG  1 
ATOM   7549 C CD  . LYS D 2 109 ? -55.567 24.657  17.687  1   69.17  ? 105 LYS C CD  1 
ATOM   7550 C CE  . LYS D 2 109 ? -57.069 24.677  17.73   1   71.59  ? 105 LYS C CE  1 
ATOM   7551 N NZ  . LYS D 2 109 ? -57.656 26.008  17.559  1   75.53  ? 105 LYS C NZ  1 
ATOM   7552 N N   . SER D 2 110 ? -50.665 23.163  19.073  1   51.19  ? 106 SER C N   1 
ATOM   7553 C CA  . SER D 2 110 ? -49.592 22.334  18.567  1   48.15  ? 106 SER C CA  1 
ATOM   7554 C C   . SER D 2 110 ? -49.029 21.524  19.733  1   45     ? 106 SER C C   1 
ATOM   7555 O O   . SER D 2 110 ? -49.013 20.301  19.682  1   44.22  ? 106 SER C O   1 
ATOM   7556 C CB  . SER D 2 110 ? -48.547 23.17   17.859  1   48.21  ? 106 SER C CB  1 
ATOM   7557 O OG  . SER D 2 110 ? -47.485 22.365  17.365  1   49.32  ? 106 SER C OG  1 
ATOM   7558 N N   . TYR D 2 111 ? -48.638 22.21   20.811  1   42.58  ? 107 TYR C N   1 
ATOM   7559 C CA  . TYR D 2 111 ? -48     21.538  21.924  1   41.07  ? 107 TYR C CA  1 
ATOM   7560 C C   . TYR D 2 111 ? -48.95  20.482  22.497  1   41.46  ? 107 TYR C C   1 
ATOM   7561 O O   . TYR D 2 111 ? -48.546 19.335  22.691  1   41.2   ? 107 TYR C O   1 
ATOM   7562 C CB  . TYR D 2 111 ? -47.456 22.573  22.908  1   42.41  ? 107 TYR C CB  1 
ATOM   7563 C CG  . TYR D 2 111 ? -46.114 23.204  22.552  1   44.92  ? 107 TYR C CG  1 
ATOM   7564 C CD1 . TYR D 2 111 ? -45.337 22.737  21.486  1   44.9   ? 107 TYR C CD1 1 
ATOM   7565 C CD2 . TYR D 2 111 ? -45.603 24.256  23.321  1   45.47  ? 107 TYR C CD2 1 
ATOM   7566 C CE1 . TYR D 2 111 ? -44.105 23.31   21.193  1   47.86  ? 107 TYR C CE1 1 
ATOM   7567 C CE2 . TYR D 2 111 ? -44.376 24.838  23.037  1   46.65  ? 107 TYR C CE2 1 
ATOM   7568 C CZ  . TYR D 2 111 ? -43.626 24.359  21.97   1   51.63  ? 107 TYR C CZ  1 
ATOM   7569 O OH  . TYR D 2 111 ? -42.406 24.907  21.672  1   58.25  ? 107 TYR C OH  1 
ATOM   7570 N N   . LEU D 2 112 ? -50.227 20.843  22.711  1   41.83  ? 108 LEU C N   1 
ATOM   7571 C CA  . LEU D 2 112 ? -51.218 19.924  23.273  1   40.89  ? 108 LEU C CA  1 
ATOM   7572 C C   . LEU D 2 112 ? -51.373 18.674  22.396  1   41.7   ? 108 LEU C C   1 
ATOM   7573 O O   . LEU D 2 112 ? -51.45  17.553  22.891  1   37.79  ? 108 LEU C O   1 
ATOM   7574 C CB  . LEU D 2 112 ? -52.562 20.633  23.464  1   39.67  ? 108 LEU C CB  1 
ATOM   7575 C CG  . LEU D 2 112 ? -53.676 19.812  24.126  1   38.92  ? 108 LEU C CG  1 
ATOM   7576 C CD1 . LEU D 2 112 ? -53.282 19.298  25.476  1   36.83  ? 108 LEU C CD1 1 
ATOM   7577 C CD2 . LEU D 2 112 ? -54.934 20.617  24.309  1   41.15  ? 108 LEU C CD2 1 
ATOM   7578 N N   . PHE D 2 113 ? -51.451 18.906  21.078  1   45.84  ? 109 PHE C N   1 
ATOM   7579 C CA  . PHE D 2 113 ? -51.68  17.872  20.083  1   46.71  ? 109 PHE C CA  1 
ATOM   7580 C C   . PHE D 2 113 ? -50.545 16.845  20.149  1   45.75  ? 109 PHE C C   1 
ATOM   7581 O O   . PHE D 2 113 ? -50.776 15.636  20.278  1   46.18  ? 109 PHE C O   1 
ATOM   7582 C CB  . PHE D 2 113 ? -51.85  18.558  18.723  1   48.29  ? 109 PHE C CB  1 
ATOM   7583 C CG  . PHE D 2 113 ? -52.321 17.632  17.616  1   51.24  ? 109 PHE C CG  1 
ATOM   7584 C CD1 . PHE D 2 113 ? -53.487 16.887  17.772  1   53.6   ? 109 PHE C CD1 1 
ATOM   7585 C CD2 . PHE D 2 113 ? -51.58  17.482  16.451  1   52.26  ? 109 PHE C CD2 1 
ATOM   7586 C CE1 . PHE D 2 113 ? -53.928 16.027  16.779  1   55.08  ? 109 PHE C CE1 1 
ATOM   7587 C CE2 . PHE D 2 113 ? -52.021 16.62   15.46   1   55.91  ? 109 PHE C CE2 1 
ATOM   7588 C CZ  . PHE D 2 113 ? -53.182 15.886  15.632  1   57.15  ? 109 PHE C CZ  1 
ATOM   7589 N N   . GLN D 2 114 ? -49.311 17.353  20.104  1   43.13  ? 110 GLN C N   1 
ATOM   7590 C CA  . GLN D 2 114 ? -48.115 16.533  20.191  1   41.46  ? 110 GLN C CA  1 
ATOM   7591 C C   . GLN D 2 114 ? -48.084 15.758  21.508  1   39.71  ? 110 GLN C C   1 
ATOM   7592 O O   . GLN D 2 114 ? -47.745 14.578  21.5    1   40.73  ? 110 GLN C O   1 
ATOM   7593 C CB  . GLN D 2 114 ? -46.875 17.408  20.049  1   41.41  ? 110 GLN C CB  1 
ATOM   7594 C CG  . GLN D 2 114 ? -46.784 18.106  18.703  1   42.52  ? 110 GLN C CG  1 
ATOM   7595 C CD  . GLN D 2 114 ? -45.476 18.835  18.511  1   44.53  ? 110 GLN C CD  1 
ATOM   7596 O OE1 . GLN D 2 114 ? -44.407 18.213  18.404  1   45.18  ? 110 GLN C OE1 1 
ATOM   7597 N NE2 . GLN D 2 114 ? -45.564 20.161  18.446  1   43.27  ? 110 GLN C NE2 1 
ATOM   7598 N N   . LEU D 2 115 ? -48.414 16.429  22.625  1   37.38  ? 111 LEU C N   1 
ATOM   7599 C CA  . LEU D 2 115 ? -48.458 15.806  23.937  1   33.95  ? 111 LEU C CA  1 
ATOM   7600 C C   . LEU D 2 115 ? -49.483 14.668  23.95   1   34.73  ? 111 LEU C C   1 
ATOM   7601 O O   . LEU D 2 115 ? -49.259 13.658  24.611  1   35.43  ? 111 LEU C O   1 
ATOM   7602 C CB  . LEU D 2 115 ? -48.771 16.834  25.023  1   31.23  ? 111 LEU C CB  1 
ATOM   7603 C CG  . LEU D 2 115 ? -47.707 17.885  25.323  1   29.59  ? 111 LEU C CG  1 
ATOM   7604 C CD1 . LEU D 2 115 ? -48.312 18.948  26.247  1   29.79  ? 111 LEU C CD1 1 
ATOM   7605 C CD2 . LEU D 2 115 ? -46.474 17.292  25.95   1   27.24  ? 111 LEU C CD2 1 
ATOM   7606 N N   . LEU D 2 116 ? -50.599 14.829  23.231  1   35.46  ? 112 LEU C N   1 
ATOM   7607 C CA  . LEU D 2 116 ? -51.674 13.848  23.206  1   37.77  ? 112 LEU C CA  1 
ATOM   7608 C C   . LEU D 2 116 ? -51.337 12.653  22.313  1   41.32  ? 112 LEU C C   1 
ATOM   7609 O O   . LEU D 2 116 ? -51.699 11.518  22.649  1   42.28  ? 112 LEU C O   1 
ATOM   7610 C CB  . LEU D 2 116 ? -52.964 14.533  22.765  1   37.68  ? 112 LEU C CB  1 
ATOM   7611 C CG  . LEU D 2 116 ? -53.609 15.415  23.835  1   36.13  ? 112 LEU C CG  1 
ATOM   7612 C CD1 . LEU D 2 116 ? -54.597 16.365  23.224  1   37.07  ? 112 LEU C CD1 1 
ATOM   7613 C CD2 . LEU D 2 116 ? -54.268 14.538  24.888  1   35.85  ? 112 LEU C CD2 1 
ATOM   7614 N N   . GLN D 2 117 ? -50.675 12.921  21.172  1   42.44  ? 113 GLN C N   1 
ATOM   7615 C CA  . GLN D 2 117 ? -50.14  11.865  20.327  1   42.51  ? 113 GLN C CA  1 
ATOM   7616 C C   . GLN D 2 117 ? -49.154 11.043  21.149  1   41.56  ? 113 GLN C C   1 
ATOM   7617 O O   . GLN D 2 117 ? -49.246 9.819   21.196  1   42.67  ? 113 GLN C O   1 
ATOM   7618 C CB  . GLN D 2 117 ? -49.476 12.441  19.078  1   43.63  ? 113 GLN C CB  1 
ATOM   7619 C CG  . GLN D 2 117 ? -50.47  13.059  18.11   1   50.08  ? 113 GLN C CG  1 
ATOM   7620 C CD  . GLN D 2 117 ? -49.862 13.563  16.82   1   58.46  ? 113 GLN C CD  1 
ATOM   7621 O OE1 . GLN D 2 117 ? -49.697 12.828  15.84   1   63.91  ? 113 GLN C OE1 1 
ATOM   7622 N NE2 . GLN D 2 117 ? -49.628 14.865  16.758  1   64.21  ? 113 GLN C NE2 1 
ATOM   7623 N N   . GLY D 2 118 ? -48.22  11.75   21.796  1   40.51  ? 114 GLY C N   1 
ATOM   7624 C CA  . GLY D 2 118 ? -47.193 11.158  22.63   1   40.01  ? 114 GLY C CA  1 
ATOM   7625 C C   . GLY D 2 118 ? -47.819 10.239  23.671  1   42.36  ? 114 GLY C C   1 
ATOM   7626 O O   . GLY D 2 118 ? -47.495 9.058   23.727  1   46.58  ? 114 GLY C O   1 
ATOM   7627 N N   . LEU D 2 119 ? -48.749 10.782  24.463  1   42.37  ? 115 LEU C N   1 
ATOM   7628 C CA  . LEU D 2 119 ? -49.36  10.053  25.568  1   40.21  ? 115 LEU C CA  1 
ATOM   7629 C C   . LEU D 2 119 ? -50.278 8.934   25.07   1   40.66  ? 115 LEU C C   1 
ATOM   7630 O O   . LEU D 2 119 ? -50.392 7.899   25.73   1   40.27  ? 115 LEU C O   1 
ATOM   7631 C CB  . LEU D 2 119 ? -50.117 11.028  26.464  1   36.8   ? 115 LEU C CB  1 
ATOM   7632 C CG  . LEU D 2 119 ? -50.883 10.398  27.626  1   34.13  ? 115 LEU C CG  1 
ATOM   7633 C CD1 . LEU D 2 119 ? -49.926 9.823   28.603  1   32.7   ? 115 LEU C CD1 1 
ATOM   7634 C CD2 . LEU D 2 119 ? -51.704 11.441  28.316  1   35.07  ? 115 LEU C CD2 1 
ATOM   7635 N N   . ALA D 2 120 ? -50.966 9.161   23.941  1   41.06  ? 116 ALA C N   1 
ATOM   7636 C CA  . ALA D 2 120 ? -51.754 8.09    23.346  1   43.46  ? 116 ALA C CA  1 
ATOM   7637 C C   . ALA D 2 120 ? -50.836 6.925   22.96   1   44.39  ? 116 ALA C C   1 
ATOM   7638 O O   . ALA D 2 120 ? -51.234 5.772   23.096  1   44.77  ? 116 ALA C O   1 
ATOM   7639 C CB  . ALA D 2 120 ? -52.592 8.576   22.182  1   41.53  ? 116 ALA C CB  1 
ATOM   7640 N N   . PHE D 2 121 ? -49.61  7.232   22.501  1   42.77  ? 117 PHE C N   1 
ATOM   7641 C CA  . PHE D 2 121 ? -48.633 6.206   22.167  1   43.52  ? 117 PHE C CA  1 
ATOM   7642 C C   . PHE D 2 121 ? -48.249 5.423   23.427  1   43.51  ? 117 PHE C C   1 
ATOM   7643 O O   . PHE D 2 121 ? -48.192 4.188   23.398  1   42.25  ? 117 PHE C O   1 
ATOM   7644 C CB  . PHE D 2 121 ? -47.405 6.765   21.438  1   42.41  ? 117 PHE C CB  1 
ATOM   7645 C CG  . PHE D 2 121 ? -46.462 5.694   20.896  1   42.07  ? 117 PHE C CG  1 
ATOM   7646 C CD1 . PHE D 2 121 ? -45.49  5.116   21.708  1   39.47  ? 117 PHE C CD1 1 
ATOM   7647 C CD2 . PHE D 2 121 ? -46.562 5.249   19.575  1   42.37  ? 117 PHE C CD2 1 
ATOM   7648 C CE1 . PHE D 2 121 ? -44.642 4.144   21.195  1   38.65  ? 117 PHE C CE1 1 
ATOM   7649 C CE2 . PHE D 2 121 ? -45.71  4.282   19.072  1   40.08  ? 117 PHE C CE2 1 
ATOM   7650 C CZ  . PHE D 2 121 ? -44.761 3.727   19.886  1   39.43  ? 117 PHE C CZ  1 
ATOM   7651 N N   . CYS D 2 122 ? -47.981 6.146   24.525  1   41.13  ? 118 CYS C N   1 
ATOM   7652 C CA  . CYS D 2 122 ? -47.725 5.481   25.79   1   41.67  ? 118 CYS C CA  1 
ATOM   7653 C C   . CYS D 2 122 ? -48.863 4.527   26.134  1   44.88  ? 118 CYS C C   1 
ATOM   7654 O O   . CYS D 2 122 ? -48.602 3.334   26.316  1   48.97  ? 118 CYS C O   1 
ATOM   7655 C CB  . CYS D 2 122 ? -47.48  6.441   26.938  1   40.75  ? 118 CYS C CB  1 
ATOM   7656 S SG  . CYS D 2 122 ? -45.928 7.347   26.739  1   43.71  ? 118 CYS C SG  1 
ATOM   7657 N N   . HIS D 2 123 ? -50.107 5.033   26.16   1   43.32  ? 119 HIS C N   1 
ATOM   7658 C CA  . HIS D 2 123 ? -51.225 4.225   26.631  1   44.36  ? 119 HIS C CA  1 
ATOM   7659 C C   . HIS D 2 123 ? -51.461 3.011   25.721  1   46.6   ? 119 HIS C C   1 
ATOM   7660 O O   . HIS D 2 123 ? -51.849 1.936   26.186  1   46.81  ? 119 HIS C O   1 
ATOM   7661 C CB  . HIS D 2 123 ? -52.47  5.088   26.848  1   44.55  ? 119 HIS C CB  1 
ATOM   7662 C CG  . HIS D 2 123 ? -52.354 6.057   27.978  1   47.17  ? 119 HIS C CG  1 
ATOM   7663 N ND1 . HIS D 2 123 ? -53.158 7.172   28.102  1   47.73  ? 119 HIS C ND1 1 
ATOM   7664 C CD2 . HIS D 2 123 ? -51.537 6.071   29.051  1   46.97  ? 119 HIS C CD2 1 
ATOM   7665 C CE1 . HIS D 2 123 ? -52.813 7.83    29.198  1   45.45  ? 119 HIS C CE1 1 
ATOM   7666 N NE2 . HIS D 2 123 ? -51.844 7.174   29.797  1   43.5   ? 119 HIS C NE2 1 
ATOM   7667 N N   . SER D 2 124 ? -51.236 3.193   24.415  1   45.35  ? 120 SER C N   1 
ATOM   7668 C CA  . SER D 2 124 ? -51.361 2.122   23.446  1   44.81  ? 120 SER C CA  1 
ATOM   7669 C C   . SER D 2 124 ? -50.367 1.009   23.742  1   44.6   ? 120 SER C C   1 
ATOM   7670 O O   . SER D 2 124 ? -50.555 -0.098  23.238  1   46.85  ? 120 SER C O   1 
ATOM   7671 C CB  . SER D 2 124 ? -51.142 2.617   22.043  1   45.87  ? 120 SER C CB  1 
ATOM   7672 O OG  . SER D 2 124 ? -52.23  3.416   21.607  1   48.02  ? 120 SER C OG  1 
ATOM   7673 N N   . HIS D 2 125 ? -49.298 1.326   24.492  1   41.16  ? 121 HIS C N   1 
ATOM   7674 C CA  . HIS D 2 125 ? -48.238 0.364   24.758  1   40.63  ? 121 HIS C CA  1 
ATOM   7675 C C   . HIS D 2 125 ? -48.167 0.004   26.234  1   39.85  ? 121 HIS C C   1 
ATOM   7676 O O   . HIS D 2 125 ? -47.103 -0.341  26.718  1   39.08  ? 121 HIS C O   1 
ATOM   7677 C CB  . HIS D 2 125 ? -46.905 0.898   24.24   1   41.67  ? 121 HIS C CB  1 
ATOM   7678 C CG  . HIS D 2 125 ? -46.916 1.055   22.758  1   48.25  ? 121 HIS C CG  1 
ATOM   7679 N ND1 . HIS D 2 125 ? -47.457 2.155   22.114  1   49.93  ? 121 HIS C ND1 1 
ATOM   7680 C CD2 . HIS D 2 125 ? -46.483 0.228   21.792  1   48.66  ? 121 HIS C CD2 1 
ATOM   7681 C CE1 . HIS D 2 125 ? -47.302 2.014   20.804  1   49.37  ? 121 HIS C CE1 1 
ATOM   7682 N NE2 . HIS D 2 125 ? -46.72  0.846   20.588  1   50.52  ? 121 HIS C NE2 1 
ATOM   7683 N N   . ARG D 2 126 ? -49.153 -0.033  26.982  1   41.7   ? 122 ARG C N   1 
ATOM   7684 C CA  . ARG D 2 126 ? -49.171 -0.542  28.382  1   41.07  ? 122 ARG C CA  1 
ATOM   7685 C C   . ARG D 2 126 ? -48.396 0.361   29.371  1   38.6   ? 122 ARG C C   1 
ATOM   7686 O O   . ARG D 2 126 ? -48.155 -0.079  30.49   1   38.97  ? 122 ARG C O   1 
ATOM   7687 C CB  . ARG D 2 126 ? -48.785 -2.028  28.291  1   42.3   ? 122 ARG C CB  1 
ATOM   7688 C CG  . ARG D 2 126 ? -47.972 -2.757  29.351  1   43.24  ? 122 ARG C CG  1 
ATOM   7689 C CD  . ARG D 2 126 ? -46.967 -3.713  28.765  1   44.99  ? 122 ARG C CD  1 
ATOM   7690 N NE  . ARG D 2 126 ? -46.28  -3.04   27.663  1   48.2   ? 122 ARG C NE  1 
ATOM   7691 C CZ  . ARG D 2 126 ? -44.978 -3.09   27.47   1   51.78  ? 122 ARG C CZ  1 
ATOM   7692 N NH1 . ARG D 2 126 ? -44.288 -1.971  27.387  1   47.87  ? 122 ARG C NH1 1 
ATOM   7693 N NH2 . ARG D 2 126 ? -44.372 -4.257  27.357  1   53.16  ? 122 ARG C NH2 1 
ATOM   7694 N N   . VAL D 2 127 ? -48.23  1.711   29.016  1   36.44  ? 123 VAL C N   1 
ATOM   7695 C CA  . VAL D 2 127 ? -47.422 2.506   29.939  1   35.62  ? 123 VAL C CA  1 
ATOM   7696 C C   . VAL D 2 127 ? -48.232 3.689   30.495  1   34.32  ? 123 VAL C C   1 
ATOM   7697 O O   . VAL D 2 127 ? -48.875 4.438   29.745  1   33.41  ? 123 VAL C O   1 
ATOM   7698 C CB  . VAL D 2 127 ? -46.11  2.987   29.275  1   34.26  ? 123 VAL C CB  1 
ATOM   7699 C CG1 . VAL D 2 127 ? -45.346 3.944   30.172  1   33.04  ? 123 VAL C CG1 1 
ATOM   7700 C CG2 . VAL D 2 127 ? -45.202 1.854   28.804  1   32.12  ? 123 VAL C CG2 1 
ATOM   7701 N N   . LEU D 2 128 ? -48.163 3.866   31.822  1   32.92  ? 124 LEU C N   1 
ATOM   7702 C CA  . LEU D 2 128 ? -48.531 5.121   32.47   1   33.35  ? 124 LEU C CA  1 
ATOM   7703 C C   . LEU D 2 128 ? -47.289 5.989   32.726  1   33.31  ? 124 LEU C C   1 
ATOM   7704 O O   . LEU D 2 128 ? -46.28  5.512   33.249  1   32.36  ? 124 LEU C O   1 
ATOM   7705 C CB  . LEU D 2 128 ? -49.249 4.827   33.782  1   31.76  ? 124 LEU C CB  1 
ATOM   7706 C CG  . LEU D 2 128 ? -50.458 3.898   33.704  1   33.47  ? 124 LEU C CG  1 
ATOM   7707 C CD1 . LEU D 2 128 ? -51.003 3.703   35.116  1   34.06  ? 124 LEU C CD1 1 
ATOM   7708 C CD2 . LEU D 2 128 ? -51.533 4.431   32.769  1   33.92  ? 124 LEU C CD2 1 
ATOM   7709 N N   . HIS D 2 129 ? -47.361 7.282   32.377  1   32.83  ? 125 HIS C N   1 
ATOM   7710 C CA  . HIS D 2 129 ? -46.253 8.178   32.663  1   31.25  ? 125 HIS C CA  1 
ATOM   7711 C C   . HIS D 2 129 ? -46.262 8.568   34.147  1   30.34  ? 125 HIS C C   1 
ATOM   7712 O O   . HIS D 2 129 ? -45.23  8.492   34.812  1   30.1   ? 125 HIS C O   1 
ATOM   7713 C CB  . HIS D 2 129 ? -46.268 9.37    31.71   1   30.61  ? 125 HIS C CB  1 
ATOM   7714 C CG  . HIS D 2 129 ? -45.121 10.278  31.933  1   30.96  ? 125 HIS C CG  1 
ATOM   7715 N ND1 . HIS D 2 129 ? -44.956 10.962  33.12   1   30.35  ? 125 HIS C ND1 1 
ATOM   7716 C CD2 . HIS D 2 129 ? -44.094 10.618  31.157  1   31.54  ? 125 HIS C CD2 1 
ATOM   7717 C CE1 . HIS D 2 129 ? -43.852 11.689  33.063  1   29.84  ? 125 HIS C CE1 1 
ATOM   7718 N NE2 . HIS D 2 129 ? -43.318 11.503  31.877  1   31.9   ? 125 HIS C NE2 1 
ATOM   7719 N N   . ARG D 2 130 ? -47.42  9.003   34.655  1   28.17  ? 126 ARG C N   1 
ATOM   7720 C CA  . ARG D 2 130 ? -47.628 9.16    36.084  1   28.16  ? 126 ARG C CA  1 
ATOM   7721 C C   . ARG D 2 130 ? -46.82  10.306  36.708  1   29.01  ? 126 ARG C C   1 
ATOM   7722 O O   . ARG D 2 130 ? -46.728 10.379  37.932  1   32.37  ? 126 ARG C O   1 
ATOM   7723 C CB  . ARG D 2 130 ? -47.375 7.825   36.794  1   26.92  ? 126 ARG C CB  1 
ATOM   7724 C CG  . ARG D 2 130 ? -48.55  6.867   36.744  1   26.92  ? 126 ARG C CG  1 
ATOM   7725 C CD  . ARG D 2 130 ? -48.428 5.863   37.852  1   26.77  ? 126 ARG C CD  1 
ATOM   7726 N NE  . ARG D 2 130 ? -47.046 5.396   37.923  1   26.54  ? 126 ARG C NE  1 
ATOM   7727 C CZ  . ARG D 2 130 ? -46.615 4.402   38.671  1   27.65  ? 126 ARG C CZ  1 
ATOM   7728 N NH1 . ARG D 2 130 ? -47.464 3.669   39.363  1   28.92  ? 126 ARG C NH1 1 
ATOM   7729 N NH2 . ARG D 2 130 ? -45.324 4.116   38.707  1   27.78  ? 126 ARG C NH2 1 
ATOM   7730 N N   . ASP D 2 131 ? -46.25  11.205  35.895  1   28.11  ? 127 ASP C N   1 
ATOM   7731 C CA  . ASP D 2 131 ? -45.582 12.398  36.399  1   28.98  ? 127 ASP C CA  1 
ATOM   7732 C C   . ASP D 2 131 ? -45.477 13.436  35.278  1   30.24  ? 127 ASP C C   1 
ATOM   7733 O O   . ASP D 2 131 ? -44.406 13.962  34.98   1   30.36  ? 127 ASP C O   1 
ATOM   7734 C CB  . ASP D 2 131 ? -44.253 12.117  37.079  1   28.25  ? 127 ASP C CB  1 
ATOM   7735 C CG  . ASP D 2 131 ? -43.711 13.34   37.796  1   31.37  ? 127 ASP C CG  1 
ATOM   7736 O OD1 . ASP D 2 131 ? -44.546 14.123  38.36   1   32.21  ? 127 ASP C OD1 1 
ATOM   7737 O OD2 . ASP D 2 131 ? -42.47  13.497  37.807  1   34.56  ? 127 ASP C OD2 1 
ATOM   7738 N N   . LEU D 2 132 ? -46.609 13.72   34.645  1   30.11  ? 128 LEU C N   1 
ATOM   7739 C CA  . LEU D 2 132 ? -46.626 14.702  33.581  1   31.76  ? 128 LEU C CA  1 
ATOM   7740 C C   . LEU D 2 132 ? -46.781 16.075  34.217  1   32.86  ? 128 LEU C C   1 
ATOM   7741 O O   . LEU D 2 132 ? -47.729 16.355  34.942  1   37.02  ? 128 LEU C O   1 
ATOM   7742 C CB  . LEU D 2 132 ? -47.747 14.364  32.595  1   32.43  ? 128 LEU C CB  1 
ATOM   7743 C CG  . LEU D 2 132 ? -47.501 13.129  31.725  1   33.2   ? 128 LEU C CG  1 
ATOM   7744 C CD1 . LEU D 2 132 ? -48.795 12.637  31.114  1   34.76  ? 128 LEU C CD1 1 
ATOM   7745 C CD2 . LEU D 2 132 ? -46.483 13.412  30.619  1   34.43  ? 128 LEU C CD2 1 
ATOM   7746 N N   . LYS D 2 133 ? -45.808 16.931  33.969  1   32.89  ? 129 LYS C N   1 
ATOM   7747 C CA  . LYS D 2 133 ? -45.767 18.251  34.58   1   33.48  ? 129 LYS C CA  1 
ATOM   7748 C C   . LYS D 2 133 ? -44.88  19.075  33.663  1   36.83  ? 129 LYS C C   1 
ATOM   7749 O O   . LYS D 2 133 ? -44.021 18.529  32.97   1   39.23  ? 129 LYS C O   1 
ATOM   7750 C CB  . LYS D 2 133 ? -45.212 18.203  36.009  1   31.25  ? 129 LYS C CB  1 
ATOM   7751 C CG  . LYS D 2 133 ? -43.788 17.675  36.122  1   31.36  ? 129 LYS C CG  1 
ATOM   7752 C CD  . LYS D 2 133 ? -43.456 17.18   37.514  1   30.96  ? 129 LYS C CD  1 
ATOM   7753 C CE  . LYS D 2 133 ? -42.152 17.737  37.965  1   34.13  ? 129 LYS C CE  1 
ATOM   7754 N NZ  . LYS D 2 133 ? -41.672 17.073  39.178  1   39.39  ? 129 LYS C NZ  1 
ATOM   7755 N N   . PRO D 2 134 ? -45.064 20.404  33.592  1   38.53  ? 130 PRO C N   1 
ATOM   7756 C CA  . PRO D 2 134 ? -44.348 21.197  32.593  1   38.17  ? 130 PRO C CA  1 
ATOM   7757 C C   . PRO D 2 134 ? -42.824 21.037  32.609  1   38.43  ? 130 PRO C C   1 
ATOM   7758 O O   . PRO D 2 134 ? -42.176 21.306  31.601  1   39.22  ? 130 PRO C O   1 
ATOM   7759 C CB  . PRO D 2 134 ? -44.831 22.596  32.969  1   38.71  ? 130 PRO C CB  1 
ATOM   7760 C CG  . PRO D 2 134 ? -46.187 22.38   33.539  1   40.86  ? 130 PRO C CG  1 
ATOM   7761 C CD  . PRO D 2 134 ? -45.989 21.178  34.429  1   39.03  ? 130 PRO C CD  1 
ATOM   7762 N N   . GLN D 2 135 ? -42.269 20.588  33.745  1   37.47  ? 131 GLN C N   1 
ATOM   7763 C CA  . GLN D 2 135 ? -40.834 20.44   33.949  1   36.27  ? 131 GLN C CA  1 
ATOM   7764 C C   . GLN D 2 135 ? -40.341 19.122  33.359  1   36.16  ? 131 GLN C C   1 
ATOM   7765 O O   . GLN D 2 135 ? -39.13  18.941  33.187  1   38.35  ? 131 GLN C O   1 
ATOM   7766 C CB  . GLN D 2 135 ? -40.466 20.445  35.431  1   36.32  ? 131 GLN C CB  1 
ATOM   7767 C CG  . GLN D 2 135 ? -40.922 21.702  36.164  1   39.31  ? 131 GLN C CG  1 
ATOM   7768 C CD  . GLN D 2 135 ? -42.384 21.728  36.572  1   40.37  ? 131 GLN C CD  1 
ATOM   7769 O OE1 . GLN D 2 135 ? -43.207 20.851  36.246  1   39.27  ? 131 GLN C OE1 1 
ATOM   7770 N NE2 . GLN D 2 135 ? -42.715 22.799  37.285  1   40.62  ? 131 GLN C NE2 1 
ATOM   7771 N N   . ASN D 2 136 ? -41.288 18.217  33.071  1   32.08  ? 132 ASN C N   1 
ATOM   7772 C CA  . ASN D 2 136 ? -40.987 16.961  32.426  1   29.24  ? 132 ASN C CA  1 
ATOM   7773 C C   . ASN D 2 136 ? -41.398 16.978  30.963  1   29.54  ? 132 ASN C C   1 
ATOM   7774 O O   . ASN D 2 136 ? -41.474 15.92   30.365  1   29.84  ? 132 ASN C O   1 
ATOM   7775 C CB  . ASN D 2 136 ? -41.669 15.815  33.147  1   29.49  ? 132 ASN C CB  1 
ATOM   7776 C CG  . ASN D 2 136 ? -41.117 15.595  34.541  1   32.53  ? 132 ASN C CG  1 
ATOM   7777 O OD1 . ASN D 2 136 ? -39.993 16.029  34.862  1   31.88  ? 132 ASN C OD1 1 
ATOM   7778 N ND2 . ASN D 2 136 ? -41.876 14.87   35.36   1   31.28  ? 132 ASN C ND2 1 
ATOM   7779 N N   . LEU D 2 137 ? -41.602 18.156  30.357  1   32.02  ? 133 LEU C N   1 
ATOM   7780 C CA  . LEU D 2 137 ? -41.941 18.204  28.932  1   32.91  ? 133 LEU C CA  1 
ATOM   7781 C C   . LEU D 2 137 ? -40.911 19.058  28.2    1   33.88  ? 133 LEU C C   1 
ATOM   7782 O O   . LEU D 2 137 ? -40.749 20.223  28.562  1   37.6   ? 133 LEU C O   1 
ATOM   7783 C CB  . LEU D 2 137 ? -43.344 18.783  28.757  1   32.26  ? 133 LEU C CB  1 
ATOM   7784 C CG  . LEU D 2 137 ? -44.478 18.008  29.433  1   31.75  ? 133 LEU C CG  1 
ATOM   7785 C CD1 . LEU D 2 137 ? -45.778 18.775  29.242  1   31.64  ? 133 LEU C CD1 1 
ATOM   7786 C CD2 . LEU D 2 137 ? -44.58  16.558  28.913  1   28.94  ? 133 LEU C CD2 1 
ATOM   7787 N N   . LEU D 2 138 ? -40.223 18.486  27.196  1   31.45  ? 134 LEU C N   1 
ATOM   7788 C CA  . LEU D 2 138 ? -39.094 19.156  26.557  1   31.23  ? 134 LEU C CA  1 
ATOM   7789 C C   . LEU D 2 138 ? -39.494 19.643  25.169  1   33.05  ? 134 LEU C C   1 
ATOM   7790 O O   . LEU D 2 138 ? -40.145 18.918  24.411  1   33.24  ? 134 LEU C O   1 
ATOM   7791 C CB  . LEU D 2 138 ? -37.881 18.232  26.453  1   29.41  ? 134 LEU C CB  1 
ATOM   7792 C CG  . LEU D 2 138 ? -37.505 17.439  27.707  1   27.2   ? 134 LEU C CG  1 
ATOM   7793 C CD1 . LEU D 2 138 ? -36.541 16.334  27.301  1   26.55  ? 134 LEU C CD1 1 
ATOM   7794 C CD2 . LEU D 2 138 ? -36.952 18.334  28.812  1   25.46  ? 134 LEU C CD2 1 
ATOM   7795 N N   . ILE D 2 139 ? -39.045 20.858  24.829  1   34.19  ? 135 ILE C N   1 
ATOM   7796 C CA  . ILE D 2 139 ? -39.319 21.453  23.532  1   35.62  ? 135 ILE C CA  1 
ATOM   7797 C C   . ILE D 2 139 ? -37.989 21.708  22.848  1   39.2   ? 135 ILE C C   1 
ATOM   7798 O O   . ILE D 2 139 ? -37.017 22.002  23.529  1   41.05  ? 135 ILE C O   1 
ATOM   7799 C CB  . ILE D 2 139 ? -40.098 22.772  23.686  1   34.6   ? 135 ILE C CB  1 
ATOM   7800 C CG1 . ILE D 2 139 ? -39.313 23.846  24.401  1   33.29  ? 135 ILE C CG1 1 
ATOM   7801 C CG2 . ILE D 2 139 ? -41.467 22.549  24.332  1   33.95  ? 135 ILE C CG2 1 
ATOM   7802 C CD1 . ILE D 2 139 ? -40.07  25.159  24.473  1   34.55  ? 135 ILE C CD1 1 
ATOM   7803 N N   . ASN D 2 140 ? -37.954 21.611  21.514  1   42.93  ? 136 ASN C N   1 
ATOM   7804 C CA  . ASN D 2 140 ? -36.823 22.129  20.751  1   46.43  ? 136 ASN C CA  1 
ATOM   7805 C C   . ASN D 2 140 ? -37.214 23.454  20.089  1   52.95  ? 136 ASN C C   1 
ATOM   7806 O O   . ASN D 2 140 ? -38.329 23.953  20.311  1   54.94  ? 136 ASN C O   1 
ATOM   7807 C CB  . ASN D 2 140 ? -36.329 21.098  19.748  1   44.25  ? 136 ASN C CB  1 
ATOM   7808 C CG  . ASN D 2 140 ? -37.417 20.636  18.803  1   43.86  ? 136 ASN C CG  1 
ATOM   7809 O OD1 . ASN D 2 140 ? -38.333 21.389  18.454  1   44.76  ? 136 ASN C OD1 1 
ATOM   7810 N ND2 . ASN D 2 140 ? -37.303 19.408  18.328  1   43.71  ? 136 ASN C ND2 1 
ATOM   7811 N N   . THR D 2 141 ? -36.318 23.962  19.226  1   56.68  ? 137 THR C N   1 
ATOM   7812 C CA  . THR D 2 141 ? -36.446 25.285  18.619  1   64.19  ? 137 THR C CA  1 
ATOM   7813 C C   . THR D 2 141 ? -37.342 25.265  17.373  1   66.99  ? 137 THR C C   1 
ATOM   7814 O O   . THR D 2 141 ? -37.549 26.319  16.761  1   69.12  ? 137 THR C O   1 
ATOM   7815 C CB  . THR D 2 141 ? -35.082 25.903  18.28   1   65.05  ? 137 THR C CB  1 
ATOM   7816 O OG1 . THR D 2 141 ? -34.575 25.26   17.112  1   69.78  ? 137 THR C OG1 1 
ATOM   7817 C CG2 . THR D 2 141 ? -34.07  25.859  19.408  1   59.77  ? 137 THR C CG2 1 
ATOM   7818 N N   . GLU D 2 142 ? -37.867 24.082  17.006  1   64.56  ? 138 GLU C N   1 
ATOM   7819 C CA  . GLU D 2 142 ? -38.557 23.89   15.737  1   64.77  ? 138 GLU C CA  1 
ATOM   7820 C C   . GLU D 2 142 ? -40.015 23.473  15.938  1   61.52  ? 138 GLU C C   1 
ATOM   7821 O O   . GLU D 2 142 ? -40.685 23.121  14.973  1   62.68  ? 138 GLU C O   1 
ATOM   7822 C CB  . GLU D 2 142 ? -37.799 22.879  14.88   1   67.93  ? 138 GLU C CB  1 
ATOM   7823 C CG  . GLU D 2 142 ? -36.295 23.138  14.85   1   74.8   ? 138 GLU C CG  1 
ATOM   7824 C CD  . GLU D 2 142 ? -35.543 22.499  13.692  1   79.09  ? 138 GLU C CD  1 
ATOM   7825 O OE1 . GLU D 2 142 ? -35.668 21.267  13.503  1   76.83  ? 138 GLU C OE1 1 
ATOM   7826 O OE2 . GLU D 2 142 ? -34.807 23.232  12.988  1   79.88  ? 138 GLU C OE2 1 
ATOM   7827 N N   . GLY D 2 143 ? -40.513 23.518  17.178  1   60.54  ? 139 GLY C N   1 
ATOM   7828 C CA  . GLY D 2 143 ? -41.953 23.459  17.41   1   59.53  ? 139 GLY C CA  1 
ATOM   7829 C C   . GLY D 2 143 ? -42.436 22.092  17.899  1   54.95  ? 139 GLY C C   1 
ATOM   7830 O O   . GLY D 2 143 ? -43.643 21.831  17.933  1   51.78  ? 139 GLY C O   1 
ATOM   7831 N N   . ALA D 2 144 ? -41.479 21.223  18.256  1   52.25  ? 140 ALA C N   1 
ATOM   7832 C CA  . ALA D 2 144 ? -41.786 19.91   18.8    1   47.39  ? 140 ALA C CA  1 
ATOM   7833 C C   . ALA D 2 144 ? -41.75  19.963  20.329  1   46.16  ? 140 ALA C C   1 
ATOM   7834 O O   . ALA D 2 144 ? -41.026 20.773  20.942  1   46.95  ? 140 ALA C O   1 
ATOM   7835 C CB  . ALA D 2 144 ? -40.82  18.892  18.248  1   44.71  ? 140 ALA C CB  1 
ATOM   7836 N N   . ILE D 2 145 ? -42.57  19.092  20.93   1   41.65  ? 141 ILE C N   1 
ATOM   7837 C CA  . ILE D 2 145 ? -42.571 18.887  22.368  1   38.45  ? 141 ILE C CA  1 
ATOM   7838 C C   . ILE D 2 145 ? -42.582 17.379  22.619  1   38.53  ? 141 ILE C C   1 
ATOM   7839 O O   . ILE D 2 145 ? -43.086 16.615  21.787  1   40.53  ? 141 ILE C O   1 
ATOM   7840 C CB  . ILE D 2 145 ? -43.789 19.596  22.961  1   36.2   ? 141 ILE C CB  1 
ATOM   7841 C CG1 . ILE D 2 145 ? -43.724 19.703  24.473  1   35.18  ? 141 ILE C CG1 1 
ATOM   7842 C CG2 . ILE D 2 145 ? -45.066 18.918  22.467  1   36.58  ? 141 ILE C CG2 1 
ATOM   7843 C CD1 . ILE D 2 145 ? -44.631 20.777  25.063  1   36.26  ? 141 ILE C CD1 1 
ATOM   7844 N N   . LYS D 2 146 ? -41.962 16.953  23.728  1   36.11  ? 142 LYS C N   1 
ATOM   7845 C CA  . LYS D 2 146 ? -41.808 15.527  23.991  1   36.8   ? 142 LYS C CA  1 
ATOM   7846 C C   . LYS D 2 146 ? -41.957 15.212  25.479  1   35.74  ? 142 LYS C C   1 
ATOM   7847 O O   . LYS D 2 146 ? -41.453 15.953  26.321  1   37.01  ? 142 LYS C O   1 
ATOM   7848 C CB  . LYS D 2 146 ? -40.441 15.043  23.494  1   36.59  ? 142 LYS C CB  1 
ATOM   7849 C CG  . LYS D 2 146 ? -40.175 15.271  22.015  1   35.42  ? 142 LYS C CG  1 
ATOM   7850 C CD  . LYS D 2 146 ? -38.837 14.715  21.557  1   35.25  ? 142 LYS C CD  1 
ATOM   7851 C CE  . LYS D 2 146 ? -38.49  15.209  20.187  1   37.33  ? 142 LYS C CE  1 
ATOM   7852 N NZ  . LYS D 2 146 ? -37.673 14.231  19.479  1   37.3   ? 142 LYS C NZ  1 
ATOM   7853 N N   . LEU D 2 147 ? -42.653 14.103  25.781  1   34.77  ? 143 LEU C N   1 
ATOM   7854 C CA  . LEU D 2 147 ? -42.73  13.534  27.125  1   33.49  ? 143 LEU C CA  1 
ATOM   7855 C C   . LEU D 2 147 ? -41.331 13.087  27.563  1   31.79  ? 143 LEU C C   1 
ATOM   7856 O O   . LEU D 2 147 ? -40.625 12.43   26.791  1   32.53  ? 143 LEU C O   1 
ATOM   7857 C CB  . LEU D 2 147 ? -43.672 12.323  27.178  1   33.36  ? 143 LEU C CB  1 
ATOM   7858 C CG  . LEU D 2 147 ? -45.047 12.416  26.515  1   32     ? 143 LEU C CG  1 
ATOM   7859 C CD1 . LEU D 2 147 ? -45.898 11.256  26.982  1   31.05  ? 143 LEU C CD1 1 
ATOM   7860 C CD2 . LEU D 2 147 ? -45.708 13.73   26.843  1   33.2   ? 143 LEU C CD2 1 
ATOM   7861 N N   . ALA D 2 148 ? -40.996 13.373  28.825  1   28.04  ? 144 ALA C N   1 
ATOM   7862 C CA  . ALA D 2 148 ? -39.687 12.979  29.386  1   28.16  ? 144 ALA C CA  1 
ATOM   7863 C C   . ALA D 2 148 ? -39.827 12.571  30.853  1   28.96  ? 144 ALA C C   1 
ATOM   7864 O O   . ALA D 2 148 ? -40.949 12.61   31.349  1   30.43  ? 144 ALA C O   1 
ATOM   7865 C CB  . ALA D 2 148 ? -38.703 14.101  29.209  1   28.77  ? 144 ALA C CB  1 
ATOM   7866 N N   . ASP D 2 149 ? -38.728 12.214  31.513  1   31.8   ? 145 ASP C N   1 
ATOM   7867 C CA  . ASP D 2 149 ? -38.724 11.7    32.915  1   34.82  ? 145 ASP C CA  1 
ATOM   7868 C C   . ASP D 2 149 ? -39.717 10.552  33.066  1   35.05  ? 145 ASP C C   1 
ATOM   7869 O O   . ASP D 2 149 ? -40.81  10.768  33.606  1   36.75  ? 145 ASP C O   1 
ATOM   7870 C CB  . ASP D 2 149 ? -38.911 12.767  33.978  1   39.48  ? 145 ASP C CB  1 
ATOM   7871 C CG  . ASP D 2 149 ? -38.139 12.541  35.267  1   47.67  ? 145 ASP C CG  1 
ATOM   7872 O OD1 . ASP D 2 149 ? -37.803 11.377  35.55   1   53.5   ? 145 ASP C OD1 1 
ATOM   7873 O OD2 . ASP D 2 149 ? -37.876 13.532  35.972  1   50.72  ? 145 ASP C OD2 1 
ATOM   7874 N N   . PHE D 2 150 ? -39.308 9.363   32.652  1   32.99  ? 146 PHE C N   1 
ATOM   7875 C CA  . PHE D 2 150 ? -40.178 8.176   32.802  1   32.03  ? 146 PHE C CA  1 
ATOM   7876 C C   . PHE D 2 150 ? -39.745 7.411   34.051  1   33.1   ? 146 PHE C C   1 
ATOM   7877 O O   . PHE D 2 150 ? -39.861 6.182   34.084  1   32.93  ? 146 PHE C O   1 
ATOM   7878 C CB  . PHE D 2 150 ? -40.091 7.411   31.481  1   31.09  ? 146 PHE C CB  1 
ATOM   7879 C CG  . PHE D 2 150 ? -41.004 7.917   30.376  1   33.83  ? 146 PHE C CG  1 
ATOM   7880 C CD1 . PHE D 2 150 ? -40.676 9.048   29.642  1   36.62  ? 146 PHE C CD1 1 
ATOM   7881 C CD2 . PHE D 2 150 ? -42.18  7.25    30.065  1   33.86  ? 146 PHE C CD2 1 
ATOM   7882 C CE1 . PHE D 2 150 ? -41.506 9.5     28.632  1   36.39  ? 146 PHE C CE1 1 
ATOM   7883 C CE2 . PHE D 2 150 ? -43.003 7.706   29.052  1   34     ? 146 PHE C CE2 1 
ATOM   7884 C CZ  . PHE D 2 150 ? -42.665 8.829   28.34   1   35.21  ? 146 PHE C CZ  1 
ATOM   7885 N N   . GLY D 2 151 ? -39.307 8.132   35.079  1   32.47  ? 147 GLY C N   1 
ATOM   7886 C CA  . GLY D 2 151 ? -38.872 7.498   36.333  1   35.45  ? 147 GLY C CA  1 
ATOM   7887 C C   . GLY D 2 151 ? -40.034 7.082   37.203  1   34.89  ? 147 GLY C C   1 
ATOM   7888 O O   . GLY D 2 151 ? -39.868 6.121   37.96   1   36.03  ? 147 GLY C O   1 
ATOM   7889 N N   . LEU D 2 152 ? -41.169 7.769   37.103  1   33.05  ? 148 LEU C N   1 
ATOM   7890 C CA  . LEU D 2 152 ? -42.38  7.349   37.851  1   34.19  ? 148 LEU C CA  1 
ATOM   7891 C C   . LEU D 2 152 ? -43.326 6.609   36.897  1   34.56  ? 148 LEU C C   1 
ATOM   7892 O O   . LEU D 2 152 ? -44.496 6.438   37.241  1   36.37  ? 148 LEU C O   1 
ATOM   7893 C CB  . LEU D 2 152 ? -43.045 8.552   38.508  1   37.03  ? 148 LEU C CB  1 
ATOM   7894 C CG  . LEU D 2 152 ? -42.49  8.957   39.874  1   38.28  ? 148 LEU C CG  1 
ATOM   7895 C CD1 . LEU D 2 152 ? -41.067 9.449   39.727  1   39.4   ? 148 LEU C CD1 1 
ATOM   7896 C CD2 . LEU D 2 152 ? -43.367 10.029  40.481  1   36.53  ? 148 LEU C CD2 1 
ATOM   7897 N N   . ALA D 2 153 ? -42.809 6.155   35.763  1   35.1   ? 149 ALA C N   1 
ATOM   7898 C CA  . ALA D 2 153 ? -43.611 5.419   34.767  1   33.09  ? 149 ALA C CA  1 
ATOM   7899 C C   . ALA D 2 153 ? -43.858 4.008   35.255  1   33.6   ? 149 ALA C C   1 
ATOM   7900 O O   . ALA D 2 153 ? -43.257 3.616   36.261  1   35.07  ? 149 ALA C O   1 
ATOM   7901 C CB  . ALA D 2 153 ? -42.904 5.384   33.447  1   30.69  ? 149 ALA C CB  1 
ATOM   7902 N N   . ARG D 2 154 ? -44.657 3.266   34.504  1   35.44  ? 150 ARG C N   1 
ATOM   7903 C CA  . ARG D 2 154 ? -45.038 1.935   34.948  1   38.39  ? 150 ARG C CA  1 
ATOM   7904 C C   . ARG D 2 154 ? -45.801 1.208   33.831  1   38.03  ? 150 ARG C C   1 
ATOM   7905 O O   . ARG D 2 154 ? -46.74  1.753   33.251  1   35.91  ? 150 ARG C O   1 
ATOM   7906 C CB  . ARG D 2 154 ? -45.81  2.101   36.266  1   39.16  ? 150 ARG C CB  1 
ATOM   7907 C CG  . ARG D 2 154 ? -46.83  1.014   36.575  1   40.43  ? 150 ARG C CG  1 
ATOM   7908 C CD  . ARG D 2 154 ? -46.304 -0.218  37.228  1   38.73  ? 150 ARG C CD  1 
ATOM   7909 N NE  . ARG D 2 154 ? -46.433 -0.234  38.686  1   37.19  ? 150 ARG C NE  1 
ATOM   7910 C CZ  . ARG D 2 154 ? -46.452 -1.367  39.407  1   36.38  ? 150 ARG C CZ  1 
ATOM   7911 N NH1 . ARG D 2 154 ? -46.418 -1.306  40.726  1   36.05  ? 150 ARG C NH1 1 
ATOM   7912 N NH2 . ARG D 2 154 ? -46.482 -2.557  38.821  1   35.4   ? 150 ARG C NH2 1 
ATOM   7913 N N   . ALA D 2 155 ? -45.357 -0.015  33.506  1   39.24  ? 151 ALA C N   1 
ATOM   7914 C CA  . ALA D 2 155 ? -46.1   -0.902  32.616  1   40.99  ? 151 ALA C CA  1 
ATOM   7915 C C   . ALA D 2 155 ? -47.296 -1.459  33.376  1   43.72  ? 151 ALA C C   1 
ATOM   7916 O O   . ALA D 2 155 ? -47.12  -2.013  34.455  1   46.06  ? 151 ALA C O   1 
ATOM   7917 C CB  . ALA D 2 155 ? -45.232 -2.03   32.119  1   37.51  ? 151 ALA C CB  1 
ATOM   7918 N N   . PHE D 2 156 ? -48.501 -1.288  32.824  1   43.75  ? 152 PHE C N   1 
ATOM   7919 C CA  . PHE D 2 156 ? -49.707 -1.754  33.493  1   42.28  ? 152 PHE C CA  1 
ATOM   7920 C C   . PHE D 2 156 ? -50.27  -2.968  32.758  1   42.4   ? 152 PHE C C   1 
ATOM   7921 O O   . PHE D 2 156 ? -49.899 -3.207  31.611  1   43.04  ? 152 PHE C O   1 
ATOM   7922 C CB  . PHE D 2 156 ? -50.712 -0.604  33.598  1   41.68  ? 152 PHE C CB  1 
ATOM   7923 C CG  . PHE D 2 156 ? -51.393 -0.104  32.328  1   41.05  ? 152 PHE C CG  1 
ATOM   7924 C CD1 . PHE D 2 156 ? -52.575 -0.678  31.876  1   40.88  ? 152 PHE C CD1 1 
ATOM   7925 C CD2 . PHE D 2 156 ? -50.881 0.983   31.625  1   39.69  ? 152 PHE C CD2 1 
ATOM   7926 C CE1 . PHE D 2 156 ? -53.207 -0.183  30.75   1   41.7   ? 152 PHE C CE1 1 
ATOM   7927 C CE2 . PHE D 2 156 ? -51.539 1.474   30.504  1   39.98  ? 152 PHE C CE2 1 
ATOM   7928 C CZ  . PHE D 2 156 ? -52.694 0.89    30.066  1   39.85  ? 152 PHE C CZ  1 
ATOM   7929 N N   . GLY D 2 157 ? -51.131 -3.729  33.453  1   41.03  ? 153 GLY C N   1 
ATOM   7930 C CA  . GLY D 2 157 ? -51.873 -4.859  32.911  1   41.25  ? 153 GLY C CA  1 
ATOM   7931 C C   . GLY D 2 157 ? -53.36  -4.513  32.827  1   43.23  ? 153 GLY C C   1 
ATOM   7932 O O   . GLY D 2 157 ? -53.781 -3.479  33.355  1   44.25  ? 153 GLY C O   1 
ATOM   7933 N N   . VAL D 2 158 ? -54.158 -5.373  32.171  1   43.95  ? 154 VAL C N   1 
ATOM   7934 C CA  . VAL D 2 158 ? -55.554 -5.067  31.866  1   44.47  ? 154 VAL C CA  1 
ATOM   7935 C C   . VAL D 2 158 ? -56.488 -6.151  32.425  1   47.14  ? 154 VAL C C   1 
ATOM   7936 O O   . VAL D 2 158 ? -56.424 -7.307  32.01   1   50.12  ? 154 VAL C O   1 
ATOM   7937 C CB  . VAL D 2 158 ? -55.734 -4.93   30.345  1   43.97  ? 154 VAL C CB  1 
ATOM   7938 C CG1 . VAL D 2 158 ? -57.157 -4.555  29.989  1   45.84  ? 154 VAL C CG1 1 
ATOM   7939 C CG2 . VAL D 2 158 ? -54.758 -3.945  29.725  1   41.45  ? 154 VAL C CG2 1 
ATOM   7940 N N   . PRO D 2 159 ? -57.398 -5.856  33.387  1   47.33  ? 155 PRO C N   1 
ATOM   7941 C CA  . PRO D 2 159 ? -57.485 -4.54   34.032  1   46.2   ? 155 PRO C CA  1 
ATOM   7942 C C   . PRO D 2 159 ? -56.342 -4.199  34.985  1   44.42  ? 155 PRO C C   1 
ATOM   7943 O O   . PRO D 2 159 ? -55.549 -5.05   35.384  1   44.71  ? 155 PRO C O   1 
ATOM   7944 C CB  . PRO D 2 159 ? -58.816 -4.591  34.799  1   46.38  ? 155 PRO C CB  1 
ATOM   7945 C CG  . PRO D 2 159 ? -59.008 -6.052  35.076  1   48.46  ? 155 PRO C CG  1 
ATOM   7946 C CD  . PRO D 2 159 ? -58.402 -6.805  33.896  1   48.7   ? 155 PRO C CD  1 
ATOM   7947 N N   . VAL D 2 160 ? -56.254 -2.91   35.328  1   42.96  ? 156 VAL C N   1 
ATOM   7948 C CA  . VAL D 2 160 ? -55.138 -2.432  36.198  1   42.9   ? 156 VAL C CA  1 
ATOM   7949 C C   . VAL D 2 160 ? -55.337 -2.922  37.638  1   45.78  ? 156 VAL C C   1 
ATOM   7950 O O   . VAL D 2 160 ? -56.495 -3.203  38.023  1   49.13  ? 156 VAL C O   1 
ATOM   7951 C CB  . VAL D 2 160 ? -55.066 -0.894  36.144  1   41.9   ? 156 VAL C CB  1 
ATOM   7952 C CG1 . VAL D 2 160 ? -54.769 -0.39   34.738  1   41.58  ? 156 VAL C CG1 1 
ATOM   7953 C CG2 . VAL D 2 160 ? -56.337 -0.248  36.683  1   42.53  ? 156 VAL C CG2 1 
ATOM   7954 N N   . ARG D 2 161 ? -54.139 -3.022  38.37   1   46.87  ? 157 ARG C N   1 
ATOM   7955 C CA  . ARG D 2 161 ? -54.194 -3.407  39.801  1   47.58  ? 157 ARG C CA  1 
ATOM   7956 C C   . ARG D 2 161 ? -53.943 -2.162  40.653  1   44.81  ? 157 ARG C C   1 
ATOM   7957 O O   . ARG D 2 161 ? -53.814 -1.078  40.08   1   44.4   ? 157 ARG C O   1 
ATOM   7958 C CB  . ARG D 2 161 ? -53.153 -4.483  40.121  1   48.97  ? 157 ARG C CB  1 
ATOM   7959 C CG  . ARG D 2 161 ? -52.202 -4.906  39.014  1   49.96  ? 157 ARG C CG  1 
ATOM   7960 C CD  . ARG D 2 161 ? -51.148 -5.827  39.599  1   53.21  ? 157 ARG C CD  1 
ATOM   7961 N NE  . ARG D 2 161 ? -50.41  -5.176  40.685  1   61.38  ? 157 ARG C NE  1 
ATOM   7962 C CZ  . ARG D 2 161 ? -49.096 -5.015  40.695  1   63.72  ? 157 ARG C CZ  1 
ATOM   7963 N NH1 . ARG D 2 161 ? -48.357 -5.593  39.768  1   60.47  ? 157 ARG C NH1 1 
ATOM   7964 N NH2 . ARG D 2 161 ? -48.526 -4.282  41.633  1   60.04  ? 157 ARG C NH2 1 
ATOM   7965 N N   . THR D 2 162 ? -54.033 -2.292  41.994  1   44.46  ? 158 THR C N   1 
ATOM   7966 C CA  . THR D 2 162 ? -53.587 -1.177  42.852  1   44.39  ? 158 THR C CA  1 
ATOM   7967 C C   . THR D 2 162 ? -52.14  -0.875  42.527  1   43.88  ? 158 THR C C   1 
ATOM   7968 O O   . THR D 2 162 ? -51.303 -1.793  42.66   1   50.17  ? 158 THR C O   1 
ATOM   7969 C CB  . THR D 2 162 ? -53.776 -1.551  44.32   1   43.09  ? 158 THR C CB  1 
ATOM   7970 O OG1 . THR D 2 162 ? -55.174 -1.787  44.452  1   42.93  ? 158 THR C OG1 1 
ATOM   7971 C CG2 . THR D 2 162 ? -53.338 -0.446  45.264  1   40.7   ? 158 THR C CG2 1 
ATOM   7972 N N   . TYR D 2 163 ? -51.85  0.356   42.098  1   40.52  ? 159 TYR C N   1 
ATOM   7973 C CA  . TYR D 2 163 ? -50.442 0.752   41.817  1   38.31  ? 159 TYR C CA  1 
ATOM   7974 C C   . TYR D 2 163 ? -49.956 1.67    42.936  1   38.61  ? 159 TYR C C   1 
ATOM   7975 O O   . TYR D 2 163 ? -50.696 1.868   43.925  1   38.37  ? 159 TYR C O   1 
ATOM   7976 C CB  . TYR D 2 163 ? -50.335 1.37    40.42   1   38.48  ? 159 TYR C CB  1 
ATOM   7977 C CG  . TYR D 2 163 ? -50.648 0.375   39.313  1   41.83  ? 159 TYR C CG  1 
ATOM   7978 C CD1 . TYR D 2 163 ? -50.073 -0.89   39.31   1   44.36  ? 159 TYR C CD1 1 
ATOM   7979 C CD2 . TYR D 2 163 ? -51.528 0.692   38.287  1   40.77  ? 159 TYR C CD2 1 
ATOM   7980 C CE1 . TYR D 2 163 ? -50.354 -1.806  38.311  1   45.43  ? 159 TYR C CE1 1 
ATOM   7981 C CE2 . TYR D 2 163 ? -51.819 -0.218  37.284  1   41.68  ? 159 TYR C CE2 1 
ATOM   7982 C CZ  . TYR D 2 163 ? -51.234 -1.471  37.298  1   45.13  ? 159 TYR C CZ  1 
ATOM   7983 O OH  . TYR D 2 163 ? -51.518 -2.374  36.316  1   47.54  ? 159 TYR C OH  1 
HETATM 7984 N N   . TPO D 2 164 ? -48.75  2.222   42.792  1   37.73  ? 160 TPO C N   1 
HETATM 7985 C CA  . TPO D 2 164 ? -48.181 3.035   43.86   1   38.74  ? 160 TPO C CA  1 
HETATM 7986 C CB  . TPO D 2 164 ? -46.745 3.483   43.546  1   37.01  ? 160 TPO C CB  1 
HETATM 7987 C CG2 . TPO D 2 164 ? -46.126 4.268   44.676  1   36.82  ? 160 TPO C CG2 1 
HETATM 7988 O OG1 . TPO D 2 164 ? -45.897 2.312   43.335  1   35.63  ? 160 TPO C OG1 1 
HETATM 7989 P P   . TPO D 2 164 ? -45.505 1.882   41.826  1   34.57  ? 160 TPO C P   1 
HETATM 7990 O O1P . TPO D 2 164 ? -44.887 3.056   41.114  1   31.63  ? 160 TPO C O1P 1 
HETATM 7991 O O2P . TPO D 2 164 ? -44.519 0.734   42.043  1   33.54  ? 160 TPO C O2P 1 
HETATM 7992 O O3P . TPO D 2 164 ? -46.832 1.511   41.183  1   35.79  ? 160 TPO C O3P 1 
HETATM 7993 C C   . TPO D 2 164 ? -49.038 4.279   44.078  1   39.65  ? 160 TPO C C   1 
HETATM 7994 O O   . TPO D 2 164 ? -49.46  4.907   43.113  1   38.48  ? 160 TPO C O   1 
ATOM   7995 N N   . HIS D 2 165 ? -49.264 4.636   45.348  1   43.73  ? 161 HIS C N   1 
ATOM   7996 C CA  . HIS D 2 165 ? -50.122 5.767   45.662  1   50.37  ? 161 HIS C CA  1 
ATOM   7997 C C   . HIS D 2 165 ? -49.367 7.079   45.449  1   50.65  ? 161 HIS C C   1 
ATOM   7998 O O   . HIS D 2 165 ? -49.899 8.03    44.885  1   50.98  ? 161 HIS C O   1 
ATOM   7999 C CB  . HIS D 2 165 ? -50.706 5.651   47.072  1   56.95  ? 161 HIS C CB  1 
ATOM   8000 C CG  . HIS D 2 165 ? -51.254 6.943   47.6    1   65.14  ? 161 HIS C CG  1 
ATOM   8001 N ND1 . HIS D 2 165 ? -52.404 7.543   47.131  1   65.35  ? 161 HIS C ND1 1 
ATOM   8002 C CD2 . HIS D 2 165 ? -50.783 7.76    48.564  1   67.52  ? 161 HIS C CD2 1 
ATOM   8003 C CE1 . HIS D 2 165 ? -52.617 8.669   47.809  1   66.5   ? 161 HIS C CE1 1 
ATOM   8004 N NE2 . HIS D 2 165 ? -51.649 8.819   48.688  1   66.93  ? 161 HIS C NE2 1 
ATOM   8005 N N   . GLU D 2 166 ? -48.082 7.047   45.896  1   52.08  ? 162 GLU C N   1 
ATOM   8006 C CA  . GLU D 2 166 ? -47.221 8.248   45.809  1   51.9   ? 162 GLU C CA  1 
ATOM   8007 C C   . GLU D 2 166 ? -46.839 8.534   44.357  1   52.31  ? 162 GLU C C   1 
ATOM   8008 O O   . GLU D 2 166 ? -45.68  8.268   44.006  1   52.37  ? 162 GLU C O   1 
ATOM   8009 C CB  . GLU D 2 166 ? -46.015 8.009   46.713  1   51.1   ? 162 GLU C CB  1 
ATOM   8010 C CG  . GLU D 2 166 ? -46.387 7.877   48.186  1   60.86  ? 162 GLU C CG  1 
ATOM   8011 C CD  . GLU D 2 166 ? -46.827 6.493   48.622  1   68.04  ? 162 GLU C CD  1 
ATOM   8012 O OE1 . GLU D 2 166 ? -46.324 5.499   48.061  1   60.33  ? 162 GLU C OE1 1 
ATOM   8013 O OE2 . GLU D 2 166 ? -47.685 6.414   49.522  1   66.96  ? 162 GLU C OE2 1 
ATOM   8014 N N   . VAL D 2 167 ? -47.792 9.132   43.575  1   47.04  ? 163 VAL C N   1 
ATOM   8015 C CA  . VAL D 2 167 ? -47.516 9.452   42.176  1   44.46  ? 163 VAL C CA  1 
ATOM   8016 C C   . VAL D 2 167 ? -48.135 10.8    41.78   1   41.72  ? 163 VAL C C   1 
ATOM   8017 O O   . VAL D 2 167 ? -49.161 11.214  42.331  1   39.89  ? 163 VAL C O   1 
ATOM   8018 C CB  . VAL D 2 167 ? -47.988 8.339   41.221  1   44.02  ? 163 VAL C CB  1 
ATOM   8019 C CG1 . VAL D 2 167 ? -47.329 7.011   41.555  1   43.68  ? 163 VAL C CG1 1 
ATOM   8020 C CG2 . VAL D 2 167 ? -49.508 8.199   41.223  1   43.66  ? 163 VAL C CG2 1 
ATOM   8021 N N   . VAL D 2 168 ? -47.501 11.429  40.769  1   39.54  ? 164 VAL C N   1 
ATOM   8022 C CA  . VAL D 2 168 ? -47.796 12.753  40.224  1   37.06  ? 164 VAL C CA  1 
ATOM   8023 C C   . VAL D 2 168 ? -47.532 13.846  41.261  1   35     ? 164 VAL C C   1 
ATOM   8024 O O   . VAL D 2 168 ? -47.974 13.744  42.397  1   34.45  ? 164 VAL C O   1 
ATOM   8025 C CB  . VAL D 2 168 ? -49.186 12.947  39.595  1   37.24  ? 164 VAL C CB  1 
ATOM   8026 C CG1 . VAL D 2 168 ? -49.175 14.131  38.652  1   36.06  ? 164 VAL C CG1 1 
ATOM   8027 C CG2 . VAL D 2 168 ? -49.686 11.715  38.855  1   38.78  ? 164 VAL C CG2 1 
ATOM   8028 N N   . THR D 2 169 ? -46.849 14.919  40.846  1   35.38  ? 165 THR C N   1 
ATOM   8029 C CA  . THR D 2 169 ? -46.748 16.121  41.672  1   38.88  ? 165 THR C CA  1 
ATOM   8030 C C   . THR D 2 169 ? -48.154 16.623  42.011  1   41.16  ? 165 THR C C   1 
ATOM   8031 O O   . THR D 2 169 ? -49.038 16.666  41.131  1   42.61  ? 165 THR C O   1 
ATOM   8032 C CB  . THR D 2 169 ? -45.936 17.217  40.974  1   40.59  ? 165 THR C CB  1 
ATOM   8033 O OG1 . THR D 2 169 ? -44.704 16.633  40.559  1   43.28  ? 165 THR C OG1 1 
ATOM   8034 C CG2 . THR D 2 169 ? -45.657 18.412  41.873  1   42.62  ? 165 THR C CG2 1 
ATOM   8035 N N   . LEU D 2 170 ? -48.329 17.044  43.278  1   38.45  ? 166 LEU C N   1 
ATOM   8036 C CA  . LEU D 2 170 ? -49.617 17.442  43.847  1   37.4   ? 166 LEU C CA  1 
ATOM   8037 C C   . LEU D 2 170 ? -50.532 18.222  42.883  1   37.66  ? 166 LEU C C   1 
ATOM   8038 O O   . LEU D 2 170 ? -51.707 17.889  42.74   1   39.69  ? 166 LEU C O   1 
ATOM   8039 C CB  . LEU D 2 170 ? -49.337 18.276  45.09   1   36.04  ? 166 LEU C CB  1 
ATOM   8040 C CG  . LEU D 2 170 ? -50.572 18.714  45.874  1   35.64  ? 166 LEU C CG  1 
ATOM   8041 C CD1 . LEU D 2 170 ? -51.311 17.535  46.495  1   34.23  ? 166 LEU C CD1 1 
ATOM   8042 C CD2 . LEU D 2 170 ? -50.152 19.752  46.912  1   36.88  ? 166 LEU C CD2 1 
ATOM   8043 N N   . TRP D 2 171 ? -50.027 19.3    42.271  1   35.42  ? 167 TRP C N   1 
ATOM   8044 C CA  . TRP D 2 171 ? -50.822 20.174  41.412  1   34.37  ? 167 TRP C CA  1 
ATOM   8045 C C   . TRP D 2 171 ? -51.438 19.408  40.235  1   34.06  ? 167 TRP C C   1 
ATOM   8046 O O   . TRP D 2 171 ? -52.517 19.73   39.728  1   33.3   ? 167 TRP C O   1 
ATOM   8047 C CB  . TRP D 2 171 ? -49.941 21.324  40.905  1   33.14  ? 167 TRP C CB  1 
ATOM   8048 C CG  . TRP D 2 171 ? -49.42  22.246  41.974  1   33.46  ? 167 TRP C CG  1 
ATOM   8049 C CD1 . TRP D 2 171 ? -49.69  22.22   43.316  1   34.43  ? 167 TRP C CD1 1 
ATOM   8050 C CD2 . TRP D 2 171 ? -48.581 23.397  41.768  1   32.72  ? 167 TRP C CD2 1 
ATOM   8051 N NE1 . TRP D 2 171 ? -49.073 23.262  43.959  1   33.29  ? 167 TRP C NE1 1 
ATOM   8052 C CE2 . TRP D 2 171 ? -48.39  24.004  43.03   1   33.39  ? 167 TRP C CE2 1 
ATOM   8053 C CE3 . TRP D 2 171 ? -47.974 23.977  40.652  1   32.76  ? 167 TRP C CE3 1 
ATOM   8054 C CZ2 . TRP D 2 171 ? -47.619 25.156  43.188  1   33.53  ? 167 TRP C CZ2 1 
ATOM   8055 C CZ3 . TRP D 2 171 ? -47.229 25.131  40.823  1   33.14  ? 167 TRP C CZ3 1 
ATOM   8056 C CH2 . TRP D 2 171 ? -47.053 25.717  42.069  1   32.03  ? 167 TRP C CH2 1 
ATOM   8057 N N   . TYR D 2 172 ? -50.725 18.373  39.797  1   33.84  ? 168 TYR C N   1 
ATOM   8058 C CA  . TYR D 2 172 ? -51.059 17.731  38.539  1   35.97  ? 168 TYR C CA  1 
ATOM   8059 C C   . TYR D 2 172 ? -51.804 16.429  38.814  1   37     ? 168 TYR C C   1 
ATOM   8060 O O   . TYR D 2 172 ? -52.266 15.776  37.867  1   35.59  ? 168 TYR C O   1 
ATOM   8061 C CB  . TYR D 2 172 ? -49.808 17.621  37.661  1   33     ? 168 TYR C CB  1 
ATOM   8062 C CG  . TYR D 2 172 ? -49.225 18.991  37.365  1   30.96  ? 168 TYR C CG  1 
ATOM   8063 C CD1 . TYR D 2 172 ? -49.709 19.737  36.303  1   31.5   ? 168 TYR C CD1 1 
ATOM   8064 C CD2 . TYR D 2 172 ? -48.263 19.566  38.187  1   30.1   ? 168 TYR C CD2 1 
ATOM   8065 C CE1 . TYR D 2 172 ? -49.219 20.999  36.007  1   31.28  ? 168 TYR C CE1 1 
ATOM   8066 C CE2 . TYR D 2 172 ? -47.775 20.835  37.921  1   30.74  ? 168 TYR C CE2 1 
ATOM   8067 C CZ  . TYR D 2 172 ? -48.244 21.543  36.821  1   31.45  ? 168 TYR C CZ  1 
ATOM   8068 O OH  . TYR D 2 172 ? -47.772 22.78   36.511  1   32.29  ? 168 TYR C OH  1 
ATOM   8069 N N   . ARG D 2 173 ? -51.976 16.136  40.118  1   37.83  ? 169 ARG C N   1 
ATOM   8070 C CA  . ARG D 2 173 ? -52.529 14.873  40.595  1   37.54  ? 169 ARG C CA  1 
ATOM   8071 C C   . ARG D 2 173 ? -54.044 14.84   40.437  1   38.9   ? 169 ARG C C   1 
ATOM   8072 O O   . ARG D 2 173 ? -54.726 15.748  40.918  1   39.71  ? 169 ARG C O   1 
ATOM   8073 C CB  . ARG D 2 173 ? -52.185 14.661  42.07   1   36.13  ? 169 ARG C CB  1 
ATOM   8074 C CG  . ARG D 2 173 ? -52.271 13.197  42.482  1   37.25  ? 169 ARG C CG  1 
ATOM   8075 C CD  . ARG D 2 173 ? -51.846 13.018  43.932  1   36.19  ? 169 ARG C CD  1 
ATOM   8076 N NE  . ARG D 2 173 ? -50.456 13.43   44.114  1   33.81  ? 169 ARG C NE  1 
ATOM   8077 C CZ  . ARG D 2 173 ? -49.959 13.795  45.274  1   33.86  ? 169 ARG C CZ  1 
ATOM   8078 N NH1 . ARG D 2 173 ? -50.754 13.852  46.331  1   35.01  ? 169 ARG C NH1 1 
ATOM   8079 N NH2 . ARG D 2 173 ? -48.683 14.118  45.369  1   32.88  ? 169 ARG C NH2 1 
ATOM   8080 N N   . ALA D 2 174 ? -54.544 13.781  39.771  1   41.21  ? 170 ALA C N   1 
ATOM   8081 C CA  . ALA D 2 174 ? -55.975 13.581  39.559  1   42.07  ? 170 ALA C CA  1 
ATOM   8082 C C   . ALA D 2 174 ? -56.65  13.267  40.885  1   46.08  ? 170 ALA C C   1 
ATOM   8083 O O   . ALA D 2 174 ? -56.016 12.723  41.791  1   50.44  ? 170 ALA C O   1 
ATOM   8084 C CB  . ALA D 2 174 ? -56.215 12.484  38.571  1   40.36  ? 170 ALA C CB  1 
ATOM   8085 N N   . PRO D 2 175 ? -57.943 13.625  41.05   1   46.82  ? 171 PRO C N   1 
ATOM   8086 C CA  . PRO D 2 175 ? -58.628 13.477  42.337  1   45.2   ? 171 PRO C CA  1 
ATOM   8087 C C   . PRO D 2 175 ? -58.737 12.043  42.85   1   44.64  ? 171 PRO C C   1 
ATOM   8088 O O   . PRO D 2 175 ? -58.749 11.842  44.058  1   42.57  ? 171 PRO C O   1 
ATOM   8089 C CB  . PRO D 2 175 ? -60.009 14.098  42.077  1   46.97  ? 171 PRO C CB  1 
ATOM   8090 C CG  . PRO D 2 175 ? -60.186 13.97   40.588  1   48.53  ? 171 PRO C CG  1 
ATOM   8091 C CD  . PRO D 2 175 ? -58.805 14.195  40.004  1   47.04  ? 171 PRO C CD  1 
ATOM   8092 N N   . GLU D 2 176 ? -58.812 11.061  41.932  1   44.25  ? 172 GLU C N   1 
ATOM   8093 C CA  . GLU D 2 176 ? -58.965 9.661   42.308  1   45.41  ? 172 GLU C CA  1 
ATOM   8094 C C   . GLU D 2 176 ? -57.775 9.18    43.137  1   47.3   ? 172 GLU C C   1 
ATOM   8095 O O   . GLU D 2 176 ? -57.931 8.33    44.03   1   50.45  ? 172 GLU C O   1 
ATOM   8096 C CB  . GLU D 2 176 ? -59.142 8.747   41.104  1   44.28  ? 172 GLU C CB  1 
ATOM   8097 C CG  . GLU D 2 176 ? -58.143 9.039   39.995  1   47.11  ? 172 GLU C CG  1 
ATOM   8098 C CD  . GLU D 2 176 ? -58.626 9.782   38.765  1   48.66  ? 172 GLU C CD  1 
ATOM   8099 O OE1 . GLU D 2 176 ? -58.293 9.315   37.643  1   46.44  ? 172 GLU C OE1 1 
ATOM   8100 O OE2 . GLU D 2 176 ? -59.349 10.791  38.931  1   49.18  ? 172 GLU C OE2 1 
ATOM   8101 N N   . ILE D 2 177 ? -56.593 9.746   42.826  1   44.91  ? 173 ILE C N   1 
ATOM   8102 C CA  . ILE D 2 177 ? -55.339 9.472   43.518  1   41.21  ? 173 ILE C CA  1 
ATOM   8103 C C   . ILE D 2 177 ? -55.332 10.181  44.868  1   42     ? 173 ILE C C   1 
ATOM   8104 O O   . ILE D 2 177 ? -54.936 9.586   45.865  1   43.16  ? 173 ILE C O   1 
ATOM   8105 C CB  . ILE D 2 177 ? -54.131 9.883   42.66   1   37.88  ? 173 ILE C CB  1 
ATOM   8106 C CG1 . ILE D 2 177 ? -54.112 9.101   41.344  1   35.75  ? 173 ILE C CG1 1 
ATOM   8107 C CG2 . ILE D 2 177 ? -52.832 9.739   43.461  1   35.53  ? 173 ILE C CG2 1 
ATOM   8108 C CD1 . ILE D 2 177 ? -52.836 9.279   40.549  1   34.53  ? 173 ILE C CD1 1 
ATOM   8109 N N   . LEU D 2 178 ? -55.775 11.448  44.885  1   42.45  ? 174 LEU C N   1 
ATOM   8110 C CA  . LEU D 2 178 ? -55.882 12.255  46.096  1   42.51  ? 174 LEU C CA  1 
ATOM   8111 C C   . LEU D 2 178 ? -56.781 11.576  47.128  1   44.62  ? 174 LEU C C   1 
ATOM   8112 O O   . LEU D 2 178 ? -56.465 11.589  48.319  1   44.14  ? 174 LEU C O   1 
ATOM   8113 C CB  . LEU D 2 178 ? -56.427 13.638  45.737  1   40.79  ? 174 LEU C CB  1 
ATOM   8114 C CG  . LEU D 2 178 ? -55.424 14.636  45.156  1   37.24  ? 174 LEU C CG  1 
ATOM   8115 C CD1 . LEU D 2 178 ? -56.115 15.789  44.459  1   36.17  ? 174 LEU C CD1 1 
ATOM   8116 C CD2 . LEU D 2 178 ? -54.531 15.103  46.28   1   36.41  ? 174 LEU C CD2 1 
ATOM   8117 N N   . LEU D 2 179 ? -57.888 10.979  46.65   1   47.24  ? 175 LEU C N   1 
ATOM   8118 C CA  . LEU D 2 179 ? -58.937 10.422  47.499  1   48.96  ? 175 LEU C CA  1 
ATOM   8119 C C   . LEU D 2 179 ? -58.632 8.983   47.918  1   50.47  ? 175 LEU C C   1 
ATOM   8120 O O   . LEU D 2 179 ? -59.373 8.401   48.716  1   55.01  ? 175 LEU C O   1 
ATOM   8121 C CB  . LEU D 2 179 ? -60.28  10.541  46.78   1   45.55  ? 175 LEU C CB  1 
ATOM   8122 C CG  . LEU D 2 179 ? -60.746 11.978  46.565  1   42.6   ? 175 LEU C CG  1 
ATOM   8123 C CD1 . LEU D 2 179 ? -61.923 12.008  45.624  1   42.52  ? 175 LEU C CD1 1 
ATOM   8124 C CD2 . LEU D 2 179 ? -61.058 12.601  47.916  1   43.18  ? 175 LEU C CD2 1 
ATOM   8125 N N   . GLY D 2 180 ? -57.561 8.409   47.362  1   47.36  ? 176 GLY C N   1 
ATOM   8126 C CA  . GLY D 2 180 ? -57.056 7.12    47.801  1   46.92  ? 176 GLY C CA  1 
ATOM   8127 C C   . GLY D 2 180 ? -57.749 5.959   47.093  1   46.69  ? 176 GLY C C   1 
ATOM   8128 O O   . GLY D 2 180 ? -57.865 4.885   47.674  1   46.39  ? 176 GLY C O   1 
ATOM   8129 N N   . CYS D 2 181 ? -58.182 6.172   45.844  1   46.45  ? 177 CYS C N   1 
ATOM   8130 C CA  . CYS D 2 181 ? -58.939 5.139   45.158  1   49.81  ? 177 CYS C CA  1 
ATOM   8131 C C   . CYS D 2 181 ? -58.083 3.888   45.025  1   50.67  ? 177 CYS C C   1 
ATOM   8132 O O   . CYS D 2 181 ? -56.91  4.003   44.693  1   52.07  ? 177 CYS C O   1 
ATOM   8133 C CB  . CYS D 2 181 ? -59.452 5.645   43.823  1   49.06  ? 177 CYS C CB  1 
ATOM   8134 S SG  . CYS D 2 181 ? -60.745 6.878   44.095  1   53.14  ? 177 CYS C SG  1 
ATOM   8135 N N   . LYS D 2 182 ? -58.668 2.719   45.328  1   50.46  ? 178 LYS C N   1 
ATOM   8136 C CA  . LYS D 2 182 ? -57.974 1.443   45.192  1   48.4   ? 178 LYS C CA  1 
ATOM   8137 C C   . LYS D 2 182 ? -57.326 1.305   43.804  1   44.81  ? 178 LYS C C   1 
ATOM   8138 O O   . LYS D 2 182 ? -56.162 0.912   43.688  1   40.5   ? 178 LYS C O   1 
ATOM   8139 C CB  . LYS D 2 182 ? -58.933 0.289   45.508  1   49.2   ? 178 LYS C CB  1 
ATOM   8140 C CG  . LYS D 2 182 ? -58.256 -1.049  45.71   1   48.45  ? 178 LYS C CG  1 
ATOM   8141 C CD  . LYS D 2 182 ? -59.254 -2.191  45.608  1   51.54  ? 178 LYS C CD  1 
ATOM   8142 C CE  . LYS D 2 182 ? -58.696 -3.548  45.921  1   52.38  ? 178 LYS C CE  1 
ATOM   8143 N NZ  . LYS D 2 182 ? -59.79  -4.482  46.214  1   53.88  ? 178 LYS C NZ  1 
ATOM   8144 N N   . TYR D 2 183 ? -58.089 1.64    42.756  1   44.5   ? 179 TYR C N   1 
ATOM   8145 C CA  . TYR D 2 183 ? -57.562 1.619   41.402  1   44.88  ? 179 TYR C CA  1 
ATOM   8146 C C   . TYR D 2 183 ? -57.497 3.031   40.835  1   45.29  ? 179 TYR C C   1 
ATOM   8147 O O   . TYR D 2 183 ? -58.184 3.93    41.326  1   46.11  ? 179 TYR C O   1 
ATOM   8148 C CB  . TYR D 2 183 ? -58.403 0.739   40.471  1   45.73  ? 179 TYR C CB  1 
ATOM   8149 C CG  . TYR D 2 183 ? -58.588 -0.675  40.991  1   47.03  ? 179 TYR C CG  1 
ATOM   8150 C CD1 . TYR D 2 183 ? -57.499 -1.427  41.414  1   46.04  ? 179 TYR C CD1 1 
ATOM   8151 C CD2 . TYR D 2 183 ? -59.855 -1.229  41.115  1   49.8   ? 179 TYR C CD2 1 
ATOM   8152 C CE1 . TYR D 2 183 ? -57.666 -2.698  41.933  1   47.69  ? 179 TYR C CE1 1 
ATOM   8153 C CE2 . TYR D 2 183 ? -60.032 -2.499  41.637  1   51.27  ? 179 TYR C CE2 1 
ATOM   8154 C CZ  . TYR D 2 183 ? -58.934 -3.238  42.04   1   49.95  ? 179 TYR C CZ  1 
ATOM   8155 O OH  . TYR D 2 183 ? -59.093 -4.492  42.546  1   51.83  ? 179 TYR C OH  1 
ATOM   8156 N N   . TYR D 2 184 ? -56.62  3.177   39.829  1   45.81  ? 180 TYR C N   1 
ATOM   8157 C CA  . TYR D 2 184 ? -56.532 4.296   38.902  1   45.32  ? 180 TYR C CA  1 
ATOM   8158 C C   . TYR D 2 184 ? -55.843 3.789   37.633  1   46.44  ? 180 TYR C C   1 
ATOM   8159 O O   . TYR D 2 184 ? -55.242 2.715   37.647  1   45.95  ? 180 TYR C O   1 
ATOM   8160 C CB  . TYR D 2 184 ? -55.801 5.49    39.517  1   42.29  ? 180 TYR C CB  1 
ATOM   8161 C CG  . TYR D 2 184 ? -54.334 5.233   39.83   1   40.72  ? 180 TYR C CG  1 
ATOM   8162 C CD1 . TYR D 2 184 ? -53.388 5.211   38.804  1   38.29  ? 180 TYR C CD1 1 
ATOM   8163 C CD2 . TYR D 2 184 ? -53.895 5.04    41.144  1   39.26  ? 180 TYR C CD2 1 
ATOM   8164 C CE1 . TYR D 2 184 ? -52.051 4.988   39.076  1   36.27  ? 180 TYR C CE1 1 
ATOM   8165 C CE2 . TYR D 2 184 ? -52.555 4.828   41.428  1   36.79  ? 180 TYR C CE2 1 
ATOM   8166 C CZ  . TYR D 2 184 ? -51.634 4.795   40.387  1   36.33  ? 180 TYR C CZ  1 
ATOM   8167 O OH  . TYR D 2 184 ? -50.295 4.569   40.597  1   35.74  ? 180 TYR C OH  1 
ATOM   8168 N N   . SER D 2 185 ? -55.923 4.582   36.554  1   48.19  ? 181 SER C N   1 
ATOM   8169 C CA  . SER D 2 185 ? -55.618 4.135   35.202  1   45.93  ? 181 SER C CA  1 
ATOM   8170 C C   . SER D 2 185 ? -55.096 5.305   34.359  1   44.66  ? 181 SER C C   1 
ATOM   8171 O O   . SER D 2 185 ? -54.593 6.284   34.903  1   43.99  ? 181 SER C O   1 
ATOM   8172 C CB  . SER D 2 185 ? -56.847 3.488   34.593  1   48.58  ? 181 SER C CB  1 
ATOM   8173 O OG  . SER D 2 185 ? -56.584 2.899   33.322  1   51.61  ? 181 SER C OG  1 
ATOM   8174 N N   . THR D 2 186 ? -55.217 5.186   33.029  1   46.01  ? 182 THR C N   1 
ATOM   8175 C CA  . THR D 2 186 ? -54.789 6.167   32.039  1   45.2   ? 182 THR C CA  1 
ATOM   8176 C C   . THR D 2 186 ? -55.433 7.536   32.292  1   47.74  ? 182 THR C C   1 
ATOM   8177 O O   . THR D 2 186 ? -54.878 8.571   31.904  1   50.07  ? 182 THR C O   1 
ATOM   8178 C CB  . THR D 2 186 ? -55.12  5.663   30.633  1   45.39  ? 182 THR C CB  1 
ATOM   8179 O OG1 . THR D 2 186 ? -56.5   5.327   30.623  1   48.4   ? 182 THR C OG1 1 
ATOM   8180 C CG2 . THR D 2 186 ? -54.352 4.424   30.216  1   44.74  ? 182 THR C CG2 1 
ATOM   8181 N N   . ALA D 2 187 ? -56.609 7.541   32.934  1   47.9   ? 183 ALA C N   1 
ATOM   8182 C CA  . ALA D 2 187 ? -57.268 8.76    33.38   1   48.73  ? 183 ALA C CA  1 
ATOM   8183 C C   . ALA D 2 187 ? -56.272 9.747   33.99   1   50.07  ? 183 ALA C C   1 
ATOM   8184 O O   . ALA D 2 187 ? -56.312 10.933  33.673  1   57.15  ? 183 ALA C O   1 
ATOM   8185 C CB  . ALA D 2 187 ? -58.354 8.439   34.368  1   48.77  ? 183 ALA C CB  1 
ATOM   8186 N N   . VAL D 2 188 ? -55.367 9.255   34.84   1   46.3   ? 184 VAL C N   1 
ATOM   8187 C CA  . VAL D 2 188 ? -54.573 10.136  35.675  1   43.7   ? 184 VAL C CA  1 
ATOM   8188 C C   . VAL D 2 188 ? -53.662 11.009  34.815  1   44.33  ? 184 VAL C C   1 
ATOM   8189 O O   . VAL D 2 188 ? -53.429 12.168  35.166  1   50.88  ? 184 VAL C O   1 
ATOM   8190 C CB  . VAL D 2 188 ? -53.794 9.412   36.786  1   41.37  ? 184 VAL C CB  1 
ATOM   8191 C CG1 . VAL D 2 188 ? -54.678 8.427   37.542  1   41.91  ? 184 VAL C CG1 1 
ATOM   8192 C CG2 . VAL D 2 188 ? -52.544 8.733   36.269  1   39.47  ? 184 VAL C CG2 1 
ATOM   8193 N N   . ASP D 2 189 ? -53.17  10.462  33.698  1   41.41  ? 185 ASP C N   1 
ATOM   8194 C CA  . ASP D 2 189 ? -52.254 11.196  32.838  1   41.36  ? 185 ASP C CA  1 
ATOM   8195 C C   . ASP D 2 189 ? -52.98  12.293  32.059  1   41.77  ? 185 ASP C C   1 
ATOM   8196 O O   . ASP D 2 189 ? -52.422 13.367  31.813  1   41.49  ? 185 ASP C O   1 
ATOM   8197 C CB  . ASP D 2 189 ? -51.501 10.277  31.892  1   41.61  ? 185 ASP C CB  1 
ATOM   8198 C CG  . ASP D 2 189 ? -50.399 9.432   32.514  1   41.09  ? 185 ASP C CG  1 
ATOM   8199 O OD1 . ASP D 2 189 ? -49.748 9.914   33.463  1   38.76  ? 185 ASP C OD1 1 
ATOM   8200 O OD2 . ASP D 2 189 ? -50.165 8.313   32.008  1   40.99  ? 185 ASP C OD2 1 
ATOM   8201 N N   . ILE D 2 190 ? -54.213 11.998  31.635  1   41.36  ? 186 ILE C N   1 
ATOM   8202 C CA  . ILE D 2 190 ? -55.03  12.971  30.934  1   41.83  ? 186 ILE C CA  1 
ATOM   8203 C C   . ILE D 2 190 ? -55.272 14.173  31.85   1   43.89  ? 186 ILE C C   1 
ATOM   8204 O O   . ILE D 2 190 ? -55.02  15.31   31.466  1   43.49  ? 186 ILE C O   1 
ATOM   8205 C CB  . ILE D 2 190 ? -56.331 12.319  30.438  1   42.44  ? 186 ILE C CB  1 
ATOM   8206 C CG1 . ILE D 2 190 ? -56.119 11.599  29.103  1   43.55  ? 186 ILE C CG1 1 
ATOM   8207 C CG2 . ILE D 2 190 ? -57.453 13.342  30.322  1   43.57  ? 186 ILE C CG2 1 
ATOM   8208 C CD1 . ILE D 2 190 ? -55.818 12.508  27.921  1   43.1   ? 186 ILE C CD1 1 
ATOM   8209 N N   . TRP D 2 191 ? -55.748 13.909  33.075  1   45.06  ? 187 TRP C N   1 
ATOM   8210 C CA  . TRP D 2 191 ? -55.977 14.956  34.056  1   43.37  ? 187 TRP C CA  1 
ATOM   8211 C C   . TRP D 2 191 ? -54.799 15.925  34.038  1   43.6   ? 187 TRP C C   1 
ATOM   8212 O O   . TRP D 2 191 ? -54.982 17.141  33.971  1   43.56  ? 187 TRP C O   1 
ATOM   8213 C CB  . TRP D 2 191 ? -56.193 14.358  35.455  1   40.32  ? 187 TRP C CB  1 
ATOM   8214 C CG  . TRP D 2 191 ? -56.435 15.386  36.532  1   39.89  ? 187 TRP C CG  1 
ATOM   8215 C CD1 . TRP D 2 191 ? -55.493 16.021  37.287  1   38.05  ? 187 TRP C CD1 1 
ATOM   8216 C CD2 . TRP D 2 191 ? -57.705 15.917  36.953  1   41.76  ? 187 TRP C CD2 1 
ATOM   8217 N NE1 . TRP D 2 191 ? -56.082 16.885  38.161  1   38.53  ? 187 TRP C NE1 1 
ATOM   8218 C CE2 . TRP D 2 191 ? -57.437 16.849  37.972  1   41.74  ? 187 TRP C CE2 1 
ATOM   8219 C CE3 . TRP D 2 191 ? -59.033 15.709  36.563  1   45.17  ? 187 TRP C CE3 1 
ATOM   8220 C CZ2 . TRP D 2 191 ? -58.458 17.563  38.601  1   45.6   ? 187 TRP C CZ2 1 
ATOM   8221 C CZ3 . TRP D 2 191 ? -60.037 16.411  37.19   1   46.31  ? 187 TRP C CZ3 1 
ATOM   8222 C CH2 . TRP D 2 191 ? -59.752 17.328  38.2    1   46.08  ? 187 TRP C CH2 1 
ATOM   8223 N N   . SER D 2 192 ? -53.587 15.358  34.067  1   43.62  ? 188 SER C N   1 
ATOM   8224 C CA  . SER D 2 192 ? -52.366 16.15   34.094  1   42.38  ? 188 SER C CA  1 
ATOM   8225 C C   . SER D 2 192 ? -52.286 17.015  32.838  1   40.25  ? 188 SER C C   1 
ATOM   8226 O O   . SER D 2 192 ? -52.043 18.217  32.944  1   38.77  ? 188 SER C O   1 
ATOM   8227 C CB  . SER D 2 192 ? -51.134 15.288  34.263  1   41.27  ? 188 SER C CB  1 
ATOM   8228 O OG  . SER D 2 192 ? -51.163 14.564  35.486  1   41.57  ? 188 SER C OG  1 
ATOM   8229 N N   . LEU D 2 193 ? -52.51  16.411  31.659  1   36.52  ? 189 LEU C N   1 
ATOM   8230 C CA  . LEU D 2 193 ? -52.41  17.196  30.444  1   35.73  ? 189 LEU C CA  1 
ATOM   8231 C C   . LEU D 2 193 ? -53.487 18.269  30.44   1   35.98  ? 189 LEU C C   1 
ATOM   8232 O O   . LEU D 2 193 ? -53.343 19.293  29.789  1   36.12  ? 189 LEU C O   1 
ATOM   8233 C CB  . LEU D 2 193 ? -52.515 16.316  29.211  1   38.41  ? 189 LEU C CB  1 
ATOM   8234 C CG  . LEU D 2 193 ? -51.299 15.442  28.901  1   39.43  ? 189 LEU C CG  1 
ATOM   8235 C CD1 . LEU D 2 193 ? -51.283 15.063  27.426  1   39.24  ? 189 LEU C CD1 1 
ATOM   8236 C CD2 . LEU D 2 193 ? -50.041 16.18   29.271  1   39.44  ? 189 LEU C CD2 1 
ATOM   8237 N N   . GLY D 2 194 ? -54.572 18.011  31.166  1   37.07  ? 190 GLY C N   1 
ATOM   8238 C CA  . GLY D 2 194 ? -55.676 18.949  31.256  1   38.75  ? 190 GLY C CA  1 
ATOM   8239 C C   . GLY D 2 194 ? -55.264 20.148  32.095  1   39.08  ? 190 GLY C C   1 
ATOM   8240 O O   . GLY D 2 194 ? -55.541 21.293  31.731  1   42.58  ? 190 GLY C O   1 
ATOM   8241 N N   . CYS D 2 195 ? -54.568 19.858  33.196  1   36.82  ? 191 CYS C N   1 
ATOM   8242 C CA  . CYS D 2 195 ? -53.979 20.901  34.012  1   36.86  ? 191 CYS C CA  1 
ATOM   8243 C C   . CYS D 2 195 ? -52.944 21.67   33.2    1   39.82  ? 191 CYS C C   1 
ATOM   8244 O O   . CYS D 2 195 ? -52.867 22.893  33.333  1   42.99  ? 191 CYS C O   1 
ATOM   8245 C CB  . CYS D 2 195 ? -53.321 20.343  35.263  1   34.07  ? 191 CYS C CB  1 
ATOM   8246 S SG  . CYS D 2 195 ? -54.521 19.523  36.331  1   35.05  ? 191 CYS C SG  1 
ATOM   8247 N N   . ILE D 2 196 ? -52.179 20.957  32.354  1   39.24  ? 192 ILE C N   1 
ATOM   8248 C CA  . ILE D 2 196 ? -51.095 21.582  31.607  1   38.02  ? 192 ILE C CA  1 
ATOM   8249 C C   . ILE D 2 196 ? -51.675 22.43   30.466  1   39.65  ? 192 ILE C C   1 
ATOM   8250 O O   . ILE D 2 196 ? -51.098 23.464  30.114  1   39.93  ? 192 ILE C O   1 
ATOM   8251 C CB  . ILE D 2 196 ? -50.038 20.539  31.178  1   35.43  ? 192 ILE C CB  1 
ATOM   8252 C CG1 . ILE D 2 196 ? -49.205 20.056  32.362  1   33.93  ? 192 ILE C CG1 1 
ATOM   8253 C CG2 . ILE D 2 196 ? -49.119 21.064  30.072  1   35.48  ? 192 ILE C CG2 1 
ATOM   8254 C CD1 . ILE D 2 196 ? -48.692 18.636  32.172  1   33.22  ? 192 ILE C CD1 1 
ATOM   8255 N N   . PHE D 2 197 ? -52.831 22.011  29.912  1   39.38  ? 193 PHE C N   1 
ATOM   8256 C CA  . PHE D 2 197 ? -53.46  22.745  28.821  1   40.47  ? 193 PHE C CA  1 
ATOM   8257 C C   . PHE D 2 197 ? -53.75  24.169  29.289  1   40.64  ? 193 PHE C C   1 
ATOM   8258 O O   . PHE D 2 197 ? -53.389 25.152  28.638  1   38.74  ? 193 PHE C O   1 
ATOM   8259 C CB  . PHE D 2 197 ? -54.74  22.042  28.373  1   41.66  ? 193 PHE C CB  1 
ATOM   8260 C CG  . PHE D 2 197 ? -55.506 22.704  27.236  1   44.25  ? 193 PHE C CG  1 
ATOM   8261 C CD1 . PHE D 2 197 ? -54.928 23.686  26.439  1   44.23  ? 193 PHE C CD1 1 
ATOM   8262 C CD2 . PHE D 2 197 ? -56.808 22.303  26.94   1   47.21  ? 193 PHE C CD2 1 
ATOM   8263 C CE1 . PHE D 2 197 ? -55.641 24.274  25.403  1   45.92  ? 193 PHE C CE1 1 
ATOM   8264 C CE2 . PHE D 2 197 ? -57.517 22.887  25.896  1   48.78  ? 193 PHE C CE2 1 
ATOM   8265 C CZ  . PHE D 2 197 ? -56.93  23.875  25.133  1   48.52  ? 193 PHE C CZ  1 
ATOM   8266 N N   . ALA D 2 198 ? -54.411 24.223  30.446  1   40.19  ? 194 ALA C N   1 
ATOM   8267 C CA  . ALA D 2 198 ? -54.808 25.44   31.119  1   40.79  ? 194 ALA C CA  1 
ATOM   8268 C C   . ALA D 2 198 ? -53.592 26.328  31.368  1   43.07  ? 194 ALA C C   1 
ATOM   8269 O O   . ALA D 2 198 ? -53.676 27.54   31.195  1   46.17  ? 194 ALA C O   1 
ATOM   8270 C CB  . ALA D 2 198 ? -55.505 25.054  32.398  1   39.56  ? 194 ALA C CB  1 
ATOM   8271 N N   . GLU D 2 199 ? -52.457 25.716  31.743  1   43.09  ? 195 GLU C N   1 
ATOM   8272 C CA  . GLU D 2 199 ? -51.277 26.453  32.189  1   42.46  ? 195 GLU C CA  1 
ATOM   8273 C C   . GLU D 2 199 ? -50.545 27.105  31.003  1   43.5   ? 195 GLU C C   1 
ATOM   8274 O O   . GLU D 2 199 ? -49.835 28.099  31.165  1   43.62  ? 195 GLU C O   1 
ATOM   8275 C CB  . GLU D 2 199 ? -50.402 25.512  33.026  1   38.73  ? 195 GLU C CB  1 
ATOM   8276 C CG  . GLU D 2 199 ? -49.298 26.216  33.812  1   38.28  ? 195 GLU C CG  1 
ATOM   8277 C CD  . GLU D 2 199 ? -48.504 25.303  34.729  1   36.96  ? 195 GLU C CD  1 
ATOM   8278 O OE1 . GLU D 2 199 ? -49.078 24.28   35.145  1   35.06  ? 195 GLU C OE1 1 
ATOM   8279 O OE2 . GLU D 2 199 ? -47.316 25.612  35.013  1   37.99  ? 195 GLU C OE2 1 
ATOM   8280 N N   . MET D 2 200 ? -50.686 26.518  29.807  1   42.57  ? 196 MET C N   1 
ATOM   8281 C CA  . MET D 2 200 ? -50.097 27.111  28.622  1   42.4   ? 196 MET C CA  1 
ATOM   8282 C C   . MET D 2 200 ? -50.869 28.39   28.293  1   43.64  ? 196 MET C C   1 
ATOM   8283 O O   . MET D 2 200 ? -50.296 29.37   27.843  1   47.51  ? 196 MET C O   1 
ATOM   8284 C CB  . MET D 2 200 ? -50.101 26.132  27.443  1   43     ? 196 MET C CB  1 
ATOM   8285 C CG  . MET D 2 200 ? -49.067 24.998  27.528  1   42.7   ? 196 MET C CG  1 
ATOM   8286 S SD  . MET D 2 200 ? -48.904 23.896  26.093  1   40.29  ? 196 MET C SD  1 
ATOM   8287 C CE  . MET D 2 200 ? -50.531 23.135  26.02   1   38.59  ? 196 MET C CE  1 
ATOM   8288 N N   . VAL D 2 201 ? -52.176 28.4    28.552  1   43.16  ? 197 VAL C N   1 
ATOM   8289 C CA  . VAL D 2 201 ? -53.026 29.526  28.194  1   43.97  ? 197 VAL C CA  1 
ATOM   8290 C C   . VAL D 2 201 ? -52.72  30.717  29.1    1   44.83  ? 197 VAL C C   1 
ATOM   8291 O O   . VAL D 2 201 ? -52.379 31.795  28.621  1   46.15  ? 197 VAL C O   1 
ATOM   8292 C CB  . VAL D 2 201 ? -54.508 29.125  28.293  1   43.18  ? 197 VAL C CB  1 
ATOM   8293 C CG1 . VAL D 2 201 ? -55.425 30.342  28.336  1   43.77  ? 197 VAL C CG1 1 
ATOM   8294 C CG2 . VAL D 2 201 ? -54.89  28.173  27.17   1   41.96  ? 197 VAL C CG2 1 
ATOM   8295 N N   . THR D 2 202 ? -52.815 30.482  30.412  1   44.16  ? 198 THR C N   1 
ATOM   8296 C CA  . THR D 2 202 ? -52.707 31.504  31.443  1   44.5   ? 198 THR C CA  1 
ATOM   8297 C C   . THR D 2 202 ? -51.265 31.658  31.931  1   44.86  ? 198 THR C C   1 
ATOM   8298 O O   . THR D 2 202 ? -50.899 32.7    32.452  1   44.25  ? 198 THR C O   1 
ATOM   8299 C CB  . THR D 2 202 ? -53.644 31.147  32.604  1   44.07  ? 198 THR C CB  1 
ATOM   8300 O OG1 . THR D 2 202 ? -53.047 30.075  33.33   1   42.1   ? 198 THR C OG1 1 
ATOM   8301 C CG2 . THR D 2 202 ? -55.047 30.759  32.163  1   43.05  ? 198 THR C CG2 1 
ATOM   8302 N N   . ARG D 2 203 ? -50.455 30.596  31.823  1   48.82  ? 199 ARG C N   1 
ATOM   8303 C CA  . ARG D 2 203 ? -49.063 30.584  32.277  1   52.35  ? 199 ARG C CA  1 
ATOM   8304 C C   . ARG D 2 203 ? -48.946 30.51   33.803  1   54.03  ? 199 ARG C C   1 
ATOM   8305 O O   . ARG D 2 203 ? -47.836 30.532  34.326  1   55.64  ? 199 ARG C O   1 
ATOM   8306 C CB  . ARG D 2 203 ? -48.234 31.746  31.719  1   53.02  ? 199 ARG C CB  1 
ATOM   8307 C CG  . ARG D 2 203 ? -47.837 31.515  30.271  1   52.75  ? 199 ARG C CG  1 
ATOM   8308 C CD  . ARG D 2 203 ? -47.948 32.811  29.48   1   57.97  ? 199 ARG C CD  1 
ATOM   8309 N NE  . ARG D 2 203 ? -49.338 33.162  29.163  1   58.81  ? 199 ARG C NE  1 
ATOM   8310 C CZ  . ARG D 2 203 ? -49.936 34.29   29.523  1   60.03  ? 199 ARG C CZ  1 
ATOM   8311 N NH1 . ARG D 2 203 ? -49.246 35.274  30.066  1   59.57  ? 199 ARG C NH1 1 
ATOM   8312 N NH2 . ARG D 2 203 ? -51.229 34.45   29.313  1   62.49  ? 199 ARG C NH2 1 
ATOM   8313 N N   . ARG D 2 204 ? -50.085 30.416  34.501  1   54.38  ? 200 ARG C N   1 
ATOM   8314 C CA  . ARG D 2 204 ? -50.139 30.05   35.909  1   51.75  ? 200 ARG C CA  1 
ATOM   8315 C C   . ARG D 2 204 ? -50.762 28.66   36.051  1   46.8   ? 200 ARG C C   1 
ATOM   8316 O O   . ARG D 2 204 ? -51.673 28.312  35.312  1   50.9   ? 200 ARG C O   1 
ATOM   8317 C CB  . ARG D 2 204 ? -50.95  31.107  36.67   1   55.49  ? 200 ARG C CB  1 
ATOM   8318 C CG  . ARG D 2 204 ? -50.14  32.371  36.908  1   65.9   ? 200 ARG C CG  1 
ATOM   8319 C CD  . ARG D 2 204 ? -50.931 33.433  37.643  1   77.6   ? 200 ARG C CD  1 
ATOM   8320 N NE  . ARG D 2 204 ? -52.195 33.527  36.906  1   86.01  ? 200 ARG C NE  1 
ATOM   8321 C CZ  . ARG D 2 204 ? -52.578 34.539  36.15   1   87.99  ? 200 ARG C CZ  1 
ATOM   8322 N NH1 . ARG D 2 204 ? -51.908 35.688  36.175  1   85.37  ? 200 ARG C NH1 1 
ATOM   8323 N NH2 . ARG D 2 204 ? -53.654 34.384  35.395  1   83.34  ? 200 ARG C NH2 1 
ATOM   8324 N N   . ALA D 2 205 ? -50.269 27.873  37.007  1   41.85  ? 201 ALA C N   1 
ATOM   8325 C CA  . ALA D 2 205 ? -50.801 26.552  37.298  1   37.51  ? 201 ALA C CA  1 
ATOM   8326 C C   . ALA D 2 205 ? -52.245 26.681  37.786  1   38.13  ? 201 ALA C C   1 
ATOM   8327 O O   . ALA D 2 205 ? -52.612 27.644  38.464  1   37.7   ? 201 ALA C O   1 
ATOM   8328 C CB  . ALA D 2 205 ? -49.93  25.841  38.305  1   34.54  ? 201 ALA C CB  1 
ATOM   8329 N N   . LEU D 2 206 ? -53.055 25.69   37.399  1   37.97  ? 202 LEU C N   1 
ATOM   8330 C CA  . LEU D 2 206 ? -54.499 25.754  37.501  1   37.28  ? 202 LEU C CA  1 
ATOM   8331 C C   . LEU D 2 206 ? -54.941 25.367  38.9    1   37.69  ? 202 LEU C C   1 
ATOM   8332 O O   . LEU D 2 206 ? -55.907 25.919  39.397  1   39.76  ? 202 LEU C O   1 
ATOM   8333 C CB  . LEU D 2 206 ? -55.119 24.815  36.472  1   36.4   ? 202 LEU C CB  1 
ATOM   8334 C CG  . LEU D 2 206 ? -56.637 24.628  36.591  1   37.5   ? 202 LEU C CG  1 
ATOM   8335 C CD1 . LEU D 2 206 ? -57.352 25.908  36.137  1   38.04  ? 202 LEU C CD1 1 
ATOM   8336 C CD2 . LEU D 2 206 ? -57.125 23.401  35.821  1   36.71  ? 202 LEU C CD2 1 
ATOM   8337 N N   . PHE D 2 207 ? -54.292 24.366  39.5    1   38.17  ? 203 PHE C N   1 
ATOM   8338 C CA  . PHE D 2 207 ? -54.695 23.902  40.823  1   39.66  ? 203 PHE C CA  1 
ATOM   8339 C C   . PHE D 2 207 ? -53.469 23.869  41.736  1   38.82  ? 203 PHE C C   1 
ATOM   8340 O O   . PHE D 2 207 ? -52.946 22.791  42.026  1   37.55  ? 203 PHE C O   1 
ATOM   8341 C CB  . PHE D 2 207 ? -55.364 22.527  40.746  1   39.43  ? 203 PHE C CB  1 
ATOM   8342 C CG  . PHE D 2 207 ? -56.636 22.448  39.918  1   42.59  ? 203 PHE C CG  1 
ATOM   8343 C CD1 . PHE D 2 207 ? -57.701 23.308  40.157  1   45.25  ? 203 PHE C CD1 1 
ATOM   8344 C CD2 . PHE D 2 207 ? -56.769 21.49   38.916  1   43.5   ? 203 PHE C CD2 1 
ATOM   8345 C CE1 . PHE D 2 207 ? -58.857 23.22   39.4    1   47.44  ? 203 PHE C CE1 1 
ATOM   8346 C CE2 . PHE D 2 207 ? -57.929 21.396  38.164  1   44.55  ? 203 PHE C CE2 1 
ATOM   8347 C CZ  . PHE D 2 207 ? -58.967 22.263  38.408  1   47.66  ? 203 PHE C CZ  1 
ATOM   8348 N N   . PRO D 2 208 ? -52.951 25.047  42.164  1   38.6   ? 204 PRO C N   1 
ATOM   8349 C CA  . PRO D 2 208 ? -51.762 25.105  43.013  1   39.43  ? 204 PRO C CA  1 
ATOM   8350 C C   . PRO D 2 208 ? -51.958 24.956  44.526  1   41.58  ? 204 PRO C C   1 
ATOM   8351 O O   . PRO D 2 208 ? -51.734 25.89   45.296  1   43.7   ? 204 PRO C O   1 
ATOM   8352 C CB  . PRO D 2 208 ? -51.145 26.475  42.585  1   38.45  ? 204 PRO C CB  1 
ATOM   8353 C CG  . PRO D 2 208 ? -52.305 27.332  42.181  1   37.86  ? 204 PRO C CG  1 
ATOM   8354 C CD  . PRO D 2 208 ? -53.399 26.383  41.739  1   38.61  ? 204 PRO C CD  1 
ATOM   8355 N N   . GLY D 2 209 ? -52.317 23.744  44.953  1   41.77  ? 205 GLY C N   1 
ATOM   8356 C CA  . GLY D 2 209 ? -52.582 23.489  46.359  1   43.57  ? 205 GLY C CA  1 
ATOM   8357 C C   . GLY D 2 209 ? -51.315 23.534  47.22   1   43.12  ? 205 GLY C C   1 
ATOM   8358 O O   . GLY D 2 209 ? -50.223 23.178  46.757  1   41.64  ? 205 GLY C O   1 
ATOM   8359 N N   . ASP D 2 210 ? -51.493 23.943  48.484  1   42.8   ? 206 ASP C N   1 
ATOM   8360 C CA  . ASP D 2 210 ? -50.42  23.878  49.453  1   44.49  ? 206 ASP C CA  1 
ATOM   8361 C C   . ASP D 2 210 ? -50.447 22.525  50.14   1   45.56  ? 206 ASP C C   1 
ATOM   8362 O O   . ASP D 2 210 ? -49.435 22.094  50.682  1   50.67  ? 206 ASP C O   1 
ATOM   8363 C CB  . ASP D 2 210 ? -50.527 24.983  50.479  1   48.4   ? 206 ASP C CB  1 
ATOM   8364 C CG  . ASP D 2 210 ? -50.624 26.375  49.878  1   51.06  ? 206 ASP C CG  1 
ATOM   8365 O OD1 . ASP D 2 210 ? -49.856 26.652  48.903  1   48.21  ? 206 ASP C OD1 1 
ATOM   8366 O OD2 . ASP D 2 210 ? -51.475 27.149  50.396  1   53.57  ? 206 ASP C OD2 1 
ATOM   8367 N N   . SER D 2 211 ? -51.611 21.879  50.109  1   43.73  ? 207 SER C N   1 
ATOM   8368 C CA  . SER D 2 211 ? -51.835 20.632  50.818  1   41.74  ? 207 SER C CA  1 
ATOM   8369 C C   . SER D 2 211 ? -52.792 19.76   50.023  1   40.79  ? 207 SER C C   1 
ATOM   8370 O O   . SER D 2 211 ? -53.345 20.195  49.018  1   40.41  ? 207 SER C O   1 
ATOM   8371 C CB  . SER D 2 211 ? -52.376 20.898  52.188  1   44.07  ? 207 SER C CB  1 
ATOM   8372 O OG  . SER D 2 211 ? -53.497 21.773  52.151  1   44.78  ? 207 SER C OG  1 
ATOM   8373 N N   . GLU D 2 212 ? -52.971 18.519  50.479  1   41.9   ? 208 GLU C N   1 
ATOM   8374 C CA  . GLU D 2 212 ? -53.907 17.613  49.834  1   41.29  ? 208 GLU C CA  1 
ATOM   8375 C C   . GLU D 2 212 ? -55.295 18.226  49.939  1   41.51  ? 208 GLU C C   1 
ATOM   8376 O O   . GLU D 2 212 ? -56.031 18.298  48.95   1   40.21  ? 208 GLU C O   1 
ATOM   8377 C CB  . GLU D 2 212 ? -53.833 16.221  50.467  1   41.78  ? 208 GLU C CB  1 
ATOM   8378 C CG  . GLU D 2 212 ? -52.73  15.386  49.83   1   41.68  ? 208 GLU C CG  1 
ATOM   8379 C CD  . GLU D 2 212 ? -52.493 14.017  50.408  1   43.35  ? 208 GLU C CD  1 
ATOM   8380 O OE1 . GLU D 2 212 ? -53.323 13.133  50.163  1   46.06  ? 208 GLU C OE1 1 
ATOM   8381 O OE2 . GLU D 2 212 ? -51.47  13.844  51.082  1   44.87  ? 208 GLU C OE2 1 
ATOM   8382 N N   . ILE D 2 213 ? -55.606 18.682  51.158  1   41.28  ? 209 ILE C N   1 
ATOM   8383 C CA  . ILE D 2 213 ? -56.916 19.233  51.447  1   42.73  ? 209 ILE C CA  1 
ATOM   8384 C C   . ILE D 2 213 ? -57.194 20.399  50.486  1   41.52  ? 209 ILE C C   1 
ATOM   8385 O O   . ILE D 2 213 ? -58.201 20.37   49.786  1   40.88  ? 209 ILE C O   1 
ATOM   8386 C CB  . ILE D 2 213 ? -57.096 19.509  52.959  1   45.68  ? 209 ILE C CB  1 
ATOM   8387 C CG1 . ILE D 2 213 ? -58.34  20.295  53.267  1   48.08  ? 209 ILE C CG1 1 
ATOM   8388 C CG2 . ILE D 2 213 ? -55.877 20.177  53.578  1   48.21  ? 209 ILE C CG2 1 
ATOM   8389 C CD1 . ILE D 2 213 ? -59.573 19.61   52.73   1   52.6   ? 209 ILE C CD1 1 
ATOM   8390 N N   . ASP D 2 214 ? -56.259 21.363  50.391  1   40.23  ? 210 ASP C N   1 
ATOM   8391 C CA  . ASP D 2 214 ? -56.359 22.525  49.52   1   38.98  ? 210 ASP C CA  1 
ATOM   8392 C C   . ASP D 2 214 ? -56.396 22.09   48.058  1   38.27  ? 210 ASP C C   1 
ATOM   8393 O O   . ASP D 2 214 ? -57.096 22.688  47.247  1   37.77  ? 210 ASP C O   1 
ATOM   8394 C CB  . ASP D 2 214 ? -55.181 23.46   49.727  1   39.68  ? 210 ASP C CB  1 
ATOM   8395 C CG  . ASP D 2 214 ? -55.223 24.796  48.997  1   41.58  ? 210 ASP C CG  1 
ATOM   8396 O OD1 . ASP D 2 214 ? -56.259 25.465  49.08   1   44.3   ? 210 ASP C OD1 1 
ATOM   8397 O OD2 . ASP D 2 214 ? -54.198 25.201  48.41   1   41.29  ? 210 ASP C OD2 1 
ATOM   8398 N N   . GLN D 2 215 ? -55.624 21.058  47.713  1   37.26  ? 211 GLN C N   1 
ATOM   8399 C CA  . GLN D 2 215 ? -55.577 20.609  46.298  1   36.59  ? 211 GLN C CA  1 
ATOM   8400 C C   . GLN D 2 215 ? -56.992 20.196  45.864  1   37.2   ? 211 GLN C C   1 
ATOM   8401 O O   . GLN D 2 215 ? -57.509 20.768  44.874  1   37.39  ? 211 GLN C O   1 
ATOM   8402 C CB  . GLN D 2 215 ? -54.594 19.451  46.129  1   36.16  ? 211 GLN C CB  1 
ATOM   8403 C CG  . GLN D 2 215 ? -54.379 19.031  44.68   1   35.71  ? 211 GLN C CG  1 
ATOM   8404 C CD  . GLN D 2 215 ? -53.67  20.079  43.852  1   35.48  ? 211 GLN C CD  1 
ATOM   8405 O OE1 . GLN D 2 215 ? -52.792 20.803  44.334  1   34.79  ? 211 GLN C OE1 1 
ATOM   8406 N NE2 . GLN D 2 215 ? -54.04  20.158  42.583  1   35.23  ? 211 GLN C NE2 1 
ATOM   8407 N N   . LEU D 2 216 ? -57.648 19.372  46.673  1   37.72  ? 212 LEU C N   1 
ATOM   8408 C CA  . LEU D 2 216 ? -59.014 18.884  46.368  1   38.74  ? 212 LEU C CA  1 
ATOM   8409 C C   . LEU D 2 216 ? -60.046 20.015  46.347  1   40.94  ? 212 LEU C C   1 
ATOM   8410 O O   . LEU D 2 216 ? -60.905 19.994  45.464  1   42.66  ? 212 LEU C O   1 
ATOM   8411 C CB  . LEU D 2 216 ? -59.331 17.856  47.446  1   39.54  ? 212 LEU C CB  1 
ATOM   8412 C CG  . LEU D 2 216 ? -58.735 16.462  47.238  1   38.79  ? 212 LEU C CG  1 
ATOM   8413 C CD1 . LEU D 2 216 ? -58.619 15.709  48.547  1   37.8   ? 212 LEU C CD1 1 
ATOM   8414 C CD2 . LEU D 2 216 ? -59.575 15.688  46.244  1   40.13  ? 212 LEU C CD2 1 
ATOM   8415 N N   . PHE D 2 217 ? -59.972 20.951  47.284  1   41.72  ? 213 PHE C N   1 
ATOM   8416 C CA  . PHE D 2 217 ? -60.967 22.054  47.375  1   43.16  ? 213 PHE C CA  1 
ATOM   8417 C C   . PHE D 2 217 ? -60.965 22.9    46.108  1   44.39  ? 213 PHE C C   1 
ATOM   8418 O O   . PHE D 2 217 ? -62.029 23.418  45.762  1   47.99  ? 213 PHE C O   1 
ATOM   8419 C CB  . PHE D 2 217 ? -60.666 22.899  48.614  1   43.46  ? 213 PHE C CB  1 
ATOM   8420 C CG  . PHE D 2 217 ? -61.28  22.381  49.905  1   44.14  ? 213 PHE C CG  1 
ATOM   8421 C CD1 . PHE D 2 217 ? -61.946 21.164  49.939  1   44.02  ? 213 PHE C CD1 1 
ATOM   8422 C CD2 . PHE D 2 217 ? -61.192 23.115  51.08   1   45.31  ? 213 PHE C CD2 1 
ATOM   8423 C CE1 . PHE D 2 217 ? -62.505 20.697  51.114  1   44.72  ? 213 PHE C CE1 1 
ATOM   8424 C CE2 . PHE D 2 217 ? -61.754 22.642  52.253  1   46.26  ? 213 PHE C CE2 1 
ATOM   8425 C CZ  . PHE D 2 217 ? -62.412 21.438  52.266  1   45.85  ? 213 PHE C CZ  1 
ATOM   8426 N N   . ARG D 2 218 ? -59.817 23.049  45.451  1   43.23  ? 214 ARG C N   1 
ATOM   8427 C CA  . ARG D 2 218 ? -59.696 23.842  44.203  1   42.54  ? 214 ARG C CA  1 
ATOM   8428 C C   . ARG D 2 218 ? -60.381 23.098  43.053  1   43.78  ? 214 ARG C C   1 
ATOM   8429 O O   . ARG D 2 218 ? -60.803 23.755  42.087  1   43.42  ? 214 ARG C O   1 
ATOM   8430 C CB  . ARG D 2 218 ? -58.21  24.068  43.939  1   39.87  ? 214 ARG C CB  1 
ATOM   8431 C CG  . ARG D 2 218 ? -57.519 24.914  44.994  1   40.43  ? 214 ARG C CG  1 
ATOM   8432 C CD  . ARG D 2 218 ? -56.016 24.879  44.819  1   38.99  ? 214 ARG C CD  1 
ATOM   8433 N NE  . ARG D 2 218 ? -55.36  25.747  45.8    1   37.92  ? 214 ARG C NE  1 
ATOM   8434 C CZ  . ARG D 2 218 ? -54.97  26.987  45.563  1   38.53  ? 214 ARG C CZ  1 
ATOM   8435 N NH1 . ARG D 2 218 ? -55.66  27.753  44.743  1   38.61  ? 214 ARG C NH1 1 
ATOM   8436 N NH2 . ARG D 2 218 ? -53.889 27.458  46.149  1   40.69  ? 214 ARG C NH2 1 
ATOM   8437 N N   . ILE D 2 219 ? -60.456 21.782  43.151  1   44.65  ? 215 ILE C N   1 
ATOM   8438 C CA  . ILE D 2 219 ? -61.177 20.992  42.122  1   48.47  ? 215 ILE C CA  1 
ATOM   8439 C C   . ILE D 2 219 ? -62.661 21.001  42.504  1   53.8   ? 215 ILE C C   1 
ATOM   8440 O O   . ILE D 2 219 ? -63.495 21.291  41.642  1   60.06  ? 215 ILE C O   1 
ATOM   8441 C CB  . ILE D 2 219 ? -60.599 19.568  42.039  1   47.31  ? 215 ILE C CB  1 
ATOM   8442 C CG1 . ILE D 2 219 ? -59.139 19.587  41.595  1   46.46  ? 215 ILE C CG1 1 
ATOM   8443 C CG2 . ILE D 2 219 ? -61.456 18.673  41.145  1   46.2   ? 215 ILE C CG2 1 
ATOM   8444 C CD1 . ILE D 2 219 ? -58.277 18.532  42.262  1   47.14  ? 215 ILE C CD1 1 
ATOM   8445 N N   . PHE D 2 220 ? -62.969 20.751  43.77   1   53.31  ? 216 PHE C N   1 
ATOM   8446 C CA  . PHE D 2 220 ? -64.386 20.685  44.197  1   52.8   ? 216 PHE C CA  1 
ATOM   8447 C C   . PHE D 2 220 ? -65.073 21.944  43.735  1   54.42  ? 216 PHE C C   1 
ATOM   8448 O O   . PHE D 2 220 ? -66.234 21.898  43.309  1   59.09  ? 216 PHE C O   1 
ATOM   8449 C CB  . PHE D 2 220 ? -64.445 20.534  45.714  1   54.75  ? 216 PHE C CB  1 
ATOM   8450 C CG  . PHE D 2 220 ? -63.964 19.204  46.272  1   58.1   ? 216 PHE C CG  1 
ATOM   8451 C CD1 . PHE D 2 220 ? -63.68  18.134  45.434  1   57.45  ? 216 PHE C CD1 1 
ATOM   8452 C CD2 . PHE D 2 220 ? -63.807 19.028  47.641  1   60.53  ? 216 PHE C CD2 1 
ATOM   8453 C CE1 . PHE D 2 220 ? -63.241 16.929  45.954  1   58.7   ? 216 PHE C CE1 1 
ATOM   8454 C CE2 . PHE D 2 220 ? -63.372 17.818  48.155  1   61.27  ? 216 PHE C CE2 1 
ATOM   8455 C CZ  . PHE D 2 220 ? -63.091 16.773  47.311  1   60.21  ? 216 PHE C CZ  1 
ATOM   8456 N N   . ARG D 2 221 ? -64.372 23.063  43.825  1   52.86  ? 217 ARG C N   1 
ATOM   8457 C CA  . ARG D 2 221 ? -64.944 24.363  43.421  1   54.92  ? 217 ARG C CA  1 
ATOM   8458 C C   . ARG D 2 221 ? -65.291 24.315  41.936  1   56.35  ? 217 ARG C C   1 
ATOM   8459 O O   . ARG D 2 221 ? -66.45  24.564  41.591  1   59.67  ? 217 ARG C O   1 
ATOM   8460 C CB  . ARG D 2 221 ? -63.888 25.42   43.756  1   53.31  ? 217 ARG C CB  1 
ATOM   8461 C CG  . ARG D 2 221 ? -63.857 26.654  42.872  1   52.48  ? 217 ARG C CG  1 
ATOM   8462 C CD  . ARG D 2 221 ? -63.033 27.718  43.554  1   52.91  ? 217 ARG C CD  1 
ATOM   8463 N NE  . ARG D 2 221 ? -61.669 27.265  43.84   1   51.69  ? 217 ARG C NE  1 
ATOM   8464 C CZ  . ARG D 2 221 ? -60.693 28.093  44.171  1   53.95  ? 217 ARG C CZ  1 
ATOM   8465 N NH1 . ARG D 2 221 ? -59.529 28.024  43.558  1   56.05  ? 217 ARG C NH1 1 
ATOM   8466 N NH2 . ARG D 2 221 ? -60.896 28.999  45.107  1   51.36  ? 217 ARG C NH2 1 
ATOM   8467 N N   . THR D 2 222 ? -64.322 23.985  41.094  1   56.04  ? 218 THR C N   1 
ATOM   8468 C CA  . THR D 2 222 ? -64.557 24.036  39.64   1   58.09  ? 218 THR C CA  1 
ATOM   8469 C C   . THR D 2 222 ? -65.682 23.103  39.279  1   59.83  ? 218 THR C C   1 
ATOM   8470 O O   . THR D 2 222 ? -66.403 23.396  38.318  1   62.58  ? 218 THR C O   1 
ATOM   8471 C CB  . THR D 2 222 ? -63.258 23.746  38.897  1   55.91  ? 218 THR C CB  1 
ATOM   8472 O OG1 . THR D 2 222 ? -63.583 24.172  37.579  1   64.09  ? 218 THR C OG1 1 
ATOM   8473 C CG2 . THR D 2 222 ? -62.832 22.292  38.921  1   51.36  ? 218 THR C CG2 1 
ATOM   8474 N N   . LEU D 2 223 ? -65.861 22.046  40.061  1   60.34  ? 219 LEU C N   1 
ATOM   8475 C CA  . LEU D 2 223 ? -66.949 21.074  39.769  1   60.39  ? 219 LEU C CA  1 
ATOM   8476 C C   . LEU D 2 223 ? -68.295 21.81   39.737  1   62.49  ? 219 LEU C C   1 
ATOM   8477 O O   . LEU D 2 223 ? -68.972 21.752  38.687  1   65.3   ? 219 LEU C O   1 
ATOM   8478 C CB  . LEU D 2 223 ? -66.978 19.976  40.829  1   60.6   ? 219 LEU C CB  1 
ATOM   8479 C CG  . LEU D 2 223 ? -65.751 19.065  40.903  1   58.3   ? 219 LEU C CG  1 
ATOM   8480 C CD1 . LEU D 2 223 ? -66.038 17.909  41.843  1   59.87  ? 219 LEU C CD1 1 
ATOM   8481 C CD2 . LEU D 2 223 ? -65.369 18.57   39.522  1   54.65  ? 219 LEU C CD2 1 
ATOM   8482 N N   . GLY D 2 224 ? -68.668 22.46   40.844  1   66.46  ? 220 GLY C N   1 
ATOM   8483 C CA  . GLY D 2 224 ? -69.978 23.136  40.939  1   73.21  ? 220 GLY C CA  1 
ATOM   8484 C C   . GLY D 2 224 ? -70.612 22.871  42.292  1   78.9   ? 220 GLY C C   1 
ATOM   8485 O O   . GLY D 2 224 ? -69.896 22.375  43.188  1   82.45  ? 220 GLY C O   1 
ATOM   8486 N N   . THR D 2 225 ? -71.903 23.184  42.448  1   80.8   ? 221 THR C N   1 
ATOM   8487 C CA  . THR D 2 225 ? -72.558 23.005  43.741  1   80.97  ? 221 THR C CA  1 
ATOM   8488 C C   . THR D 2 225 ? -73.248 21.636  43.745  1   83.98  ? 221 THR C C   1 
ATOM   8489 O O   . THR D 2 225 ? -73.446 21.071  42.671  1   84.64  ? 221 THR C O   1 
ATOM   8490 C CB  . THR D 2 225 ? -73.474 24.19   44.081  1   78.94  ? 221 THR C CB  1 
ATOM   8491 O OG1 . THR D 2 225 ? -74.627 24.14   43.246  1   79.03  ? 221 THR C OG1 1 
ATOM   8492 C CG2 . THR D 2 225 ? -72.765 25.533  43.975  1   75.03  ? 221 THR C CG2 1 
ATOM   8493 N N   . PRO D 2 226 ? -73.587 21.024  44.916  1   84.99  ? 222 PRO C N   1 
ATOM   8494 C CA  . PRO D 2 226 ? -74.039 19.624  44.947  1   84.65  ? 222 PRO C CA  1 
ATOM   8495 C C   . PRO D 2 226 ? -75.342 19.348  44.201  1   87.62  ? 222 PRO C C   1 
ATOM   8496 O O   . PRO D 2 226 ? -76.2   20.224  44.117  1   90.59  ? 222 PRO C O   1 
ATOM   8497 C CB  . PRO D 2 226 ? -74.173 19.291  46.444  1   83.36  ? 222 PRO C CB  1 
ATOM   8498 C CG  . PRO D 2 226 ? -73.427 20.393  47.154  1   81.61  ? 222 PRO C CG  1 
ATOM   8499 C CD  . PRO D 2 226 ? -73.537 21.618  46.265  1   81.91  ? 222 PRO C CD  1 
ATOM   8500 N N   . ASP D 2 227 ? -75.479 18.118  43.69   1   88.98  ? 223 ASP C N   1 
ATOM   8501 C CA  . ASP D 2 227 ? -76.689 17.662  43.023  1   93.91  ? 223 ASP C CA  1 
ATOM   8502 C C   . ASP D 2 227 ? -77.283 16.511  43.844  1   96.29  ? 223 ASP C C   1 
ATOM   8503 O O   . ASP D 2 227 ? -78.258 16.702  44.584  1   94.09  ? 223 ASP C O   1 
ATOM   8504 C CB  . ASP D 2 227 ? -76.419 17.41   41.539  1   93.66  ? 223 ASP C CB  1 
ATOM   8505 C CG  . ASP D 2 227 ? -77.635 17.305  40.622  1   97.51  ? 223 ASP C CG  1 
ATOM   8506 O OD1 . ASP D 2 227 ? -78.602 18.081  40.8    1   98.94  ? 223 ASP C OD1 1 
ATOM   8507 O OD2 . ASP D 2 227 ? -77.595 16.476  39.691  1   99.91  ? 223 ASP C OD2 1 
ATOM   8508 N N   . GLU D 2 228 ? -76.638 15.335  43.742  1   97.85  ? 224 GLU C N   1 
ATOM   8509 C CA  . GLU D 2 228 ? -77.095 14.1    44.367  1   99.22  ? 224 GLU C CA  1 
ATOM   8510 C C   . GLU D 2 228 ? -76.123 13.653  45.46   1   93.62  ? 224 GLU C C   1 
ATOM   8511 O O   . GLU D 2 228 ? -76.517 13.547  46.622  1   93.37  ? 224 GLU C O   1 
ATOM   8512 C CB  . GLU D 2 228 ? -77.268 12.981  43.34   1   103.23 ? 224 GLU C CB  1 
ATOM   8513 C CG  . GLU D 2 228 ? -77.947 11.75   43.934  1   111    ? 224 GLU C CG  1 
ATOM   8514 C CD  . GLU D 2 228 ? -77.777 10.48   43.122  1   116.34 ? 224 GLU C CD  1 
ATOM   8515 O OE1 . GLU D 2 228 ? -78.275 10.426  41.98   1   120.43 ? 224 GLU C OE1 1 
ATOM   8516 O OE2 . GLU D 2 228 ? -77.128 9.545   43.635  1   117.07 ? 224 GLU C OE2 1 
ATOM   8517 N N   . VAL D 2 229 ? -74.878 13.342  45.064  1   87.97  ? 225 VAL C N   1 
ATOM   8518 C CA  . VAL D 2 229 ? -73.781 13.052  45.987  1   83.07  ? 225 VAL C CA  1 
ATOM   8519 C C   . VAL D 2 229 ? -73.266 14.392  46.537  1   79.89  ? 225 VAL C C   1 
ATOM   8520 O O   . VAL D 2 229 ? -72.693 15.182  45.786  1   77.48  ? 225 VAL C O   1 
ATOM   8521 C CB  . VAL D 2 229 ? -72.646 12.2    45.353  1   79.02  ? 225 VAL C CB  1 
ATOM   8522 C CG1 . VAL D 2 229 ? -71.698 11.603  46.388  1   75.9   ? 225 VAL C CG1 1 
ATOM   8523 C CG2 . VAL D 2 229 ? -73.151 11.096  44.426  1   77.75  ? 225 VAL C CG2 1 
ATOM   8524 N N   . VAL D 2 230 ? -73.475 14.625  47.846  1   78     ? 226 VAL C N   1 
ATOM   8525 C CA  . VAL D 2 230 ? -73.36  15.928  48.492  1   76.54  ? 226 VAL C CA  1 
ATOM   8526 C C   . VAL D 2 230 ? -71.903 16.296  48.804  1   75.65  ? 226 VAL C C   1 
ATOM   8527 O O   . VAL D 2 230 ? -71.42  17.376  48.431  1   76.17  ? 226 VAL C O   1 
ATOM   8528 C CB  . VAL D 2 230 ? -74.231 15.951  49.761  1   75.83  ? 226 VAL C CB  1 
ATOM   8529 C CG1 . VAL D 2 230 ? -73.755 16.989  50.779  1   74.36  ? 226 VAL C CG1 1 
ATOM   8530 C CG2 . VAL D 2 230 ? -75.697 16.139  49.411  1   76.93  ? 226 VAL C CG2 1 
ATOM   8531 N N   . TRP D 2 231 ? -71.184 15.387  49.447  1   73.94  ? 227 TRP C N   1 
ATOM   8532 C CA  . TRP D 2 231 ? -69.743 15.658  49.638  1   71.61  ? 227 TRP C CA  1 
ATOM   8533 C C   . TRP D 2 231 ? -68.973 14.838  48.607  1   70.62  ? 227 TRP C C   1 
ATOM   8534 O O   . TRP D 2 231 ? -69.106 13.604  48.591  1   71.79  ? 227 TRP C O   1 
ATOM   8535 C CB  . TRP D 2 231 ? -69.295 15.346  51.068  1   73.19  ? 227 TRP C CB  1 
ATOM   8536 C CG  . TRP D 2 231 ? -67.881 15.777  51.339  1   74.01  ? 227 TRP C CG  1 
ATOM   8537 C CD1 . TRP D 2 231 ? -66.808 14.978  51.596  1   70.03  ? 227 TRP C CD1 1 
ATOM   8538 C CD2 . TRP D 2 231 ? -67.39  17.133  51.362  1   74.13  ? 227 TRP C CD2 1 
ATOM   8539 N NE1 . TRP D 2 231 ? -65.686 15.739  51.782  1   68.47  ? 227 TRP C NE1 1 
ATOM   8540 C CE2 . TRP D 2 231 ? -66.011 17.062  51.645  1   69.15  ? 227 TRP C CE2 1 
ATOM   8541 C CE3 . TRP D 2 231 ? -67.978 18.388  51.176  1   74.88  ? 227 TRP C CE3 1 
ATOM   8542 C CZ2 . TRP D 2 231 ? -65.217 18.2    51.744  1   66.96  ? 227 TRP C CZ2 1 
ATOM   8543 C CZ3 . TRP D 2 231 ? -67.19  19.511  51.271  1   71.73  ? 227 TRP C CZ3 1 
ATOM   8544 C CH2 . TRP D 2 231 ? -65.83  19.415  51.552  1   68.67  ? 227 TRP C CH2 1 
ATOM   8545 N N   . PRO D 2 232 ? -68.193 15.484  47.721  1   67.74  ? 228 PRO C N   1 
ATOM   8546 C CA  . PRO D 2 232 ? -67.49  14.759  46.677  1   65.75  ? 228 PRO C CA  1 
ATOM   8547 C C   . PRO D 2 232 ? -66.187 14.1    47.122  1   62.99  ? 228 PRO C C   1 
ATOM   8548 O O   . PRO D 2 232 ? -65.58  13.373  46.324  1   61.48  ? 228 PRO C O   1 
ATOM   8549 C CB  . PRO D 2 232 ? -67.285 15.904  45.675  1   65.91  ? 228 PRO C CB  1 
ATOM   8550 C CG  . PRO D 2 232 ? -67.061 17.12   46.533  1   65.57  ? 228 PRO C CG  1 
ATOM   8551 C CD  . PRO D 2 232 ? -67.994 16.921  47.702  1   68.57  ? 228 PRO C CD  1 
ATOM   8552 N N   . GLY D 2 233 ? -65.784 14.316  48.372  1   61.81  ? 229 GLY C N   1 
ATOM   8553 C CA  . GLY D 2 233 ? -64.539 13.736  48.901  1   61.95  ? 229 GLY C CA  1 
ATOM   8554 C C   . GLY D 2 233 ? -64.732 12.281  49.234  1   67.4   ? 229 GLY C C   1 
ATOM   8555 O O   . GLY D 2 233 ? -64.406 11.888  50.366  1   67.67  ? 229 GLY C O   1 
ATOM   8556 N N   . VAL D 2 234 ? -65.239 11.52   48.266  1   72.32  ? 230 VAL C N   1 
ATOM   8557 C CA  . VAL D 2 234 ? -65.535 10.081  48.497  1   73.21  ? 230 VAL C CA  1 
ATOM   8558 C C   . VAL D 2 234 ? -64.89  9.239   47.387  1   72.42  ? 230 VAL C C   1 
ATOM   8559 O O   . VAL D 2 234 ? -64.965 9.641   46.217  1   69.01  ? 230 VAL C O   1 
ATOM   8560 C CB  . VAL D 2 234 ? -67.066 9.92    48.569  1   74.56  ? 230 VAL C CB  1 
ATOM   8561 C CG1 . VAL D 2 234 ? -67.779 10.384  47.305  1   73.72  ? 230 VAL C CG1 1 
ATOM   8562 C CG2 . VAL D 2 234 ? -67.486 8.514   48.967  1   79.13  ? 230 VAL C CG2 1 
ATOM   8563 N N   . THR D 2 235 ? -64.295 8.101   47.746  1   74.83  ? 231 THR C N   1 
ATOM   8564 C CA  . THR D 2 235 ? -63.677 7.191   46.76   1   75.97  ? 231 THR C CA  1 
ATOM   8565 C C   . THR D 2 235 ? -64.707 6.775   45.738  1   81.3   ? 231 THR C C   1 
ATOM   8566 O O   . THR D 2 235 ? -64.308 6.214   44.704  1   83.03  ? 231 THR C O   1 
ATOM   8567 C CB  . THR D 2 235 ? -63.098 5.986   47.494  1   73.24  ? 231 THR C CB  1 
ATOM   8568 O OG1 . THR D 2 235 ? -64.013 5.713   48.549  1   75.64  ? 231 THR C OG1 1 
ATOM   8569 C CG2 . THR D 2 235 ? -61.718 6.261   48.06   1   68.46  ? 231 THR C CG2 1 
ATOM   8570 N N   . SER D 2 236 ? -65.942 6.925   45.951  1   83.51  ? 232 SER C N   1 
ATOM   8571 C CA  . SER D 2 236 ? -66.978 6.596   44.946  1   83.99  ? 232 SER C CA  1 
ATOM   8572 C C   . SER D 2 236 ? -67.073 7.812   44.038  1   84.35  ? 232 SER C C   1 
ATOM   8573 O O   . SER D 2 236 ? -67.895 8.692   44.326  1   85.41  ? 232 SER C O   1 
ATOM   8574 C CB  . SER D 2 236 ? -68.284 6.317   45.6    1   83.73  ? 232 SER C CB  1 
ATOM   8575 O OG  . SER D 2 236 ? -68.842 7.487   46.178  1   81.41  ? 232 SER C OG  1 
ATOM   8576 N N   . MET D 2 237 ? -66.276 7.911   43.068  1   82.41  ? 233 MET C N   1 
ATOM   8577 C CA  . MET D 2 237 ? -66.216 9.102   42.185  1   81.82  ? 233 MET C CA  1 
ATOM   8578 C C   . MET D 2 237 ? -67.624 9.497   41.753  1   81.82  ? 233 MET C C   1 
ATOM   8579 O O   . MET D 2 237 ? -68.232 8.768   40.953  1   82.67  ? 233 MET C O   1 
ATOM   8580 C CB  . MET D 2 237 ? -65.353 8.859   40.946  1   82.08  ? 233 MET C CB  1 
ATOM   8581 C CG  . MET D 2 237 ? -63.87  8.743   41.248  1   78.68  ? 233 MET C CG  1 
ATOM   8582 S SD  . MET D 2 237 ? -63.121 10.193  42.017  1   74.08  ? 233 MET C SD  1 
ATOM   8583 C CE  . MET D 2 237 ? -62.941 9.503   43.663  1   70.8   ? 233 MET C CE  1 
ATOM   8584 N N   . PRO D 2 238 ? -68.156 10.625  42.257  1   80.13  ? 234 PRO C N   1 
ATOM   8585 C CA  . PRO D 2 238 ? -69.46  11.08   41.816  1   80.9   ? 234 PRO C CA  1 
ATOM   8586 C C   . PRO D 2 238 ? -69.349 11.673  40.421  1   80.34  ? 234 PRO C C   1 
ATOM   8587 O O   . PRO D 2 238 ? -68.232 11.999  39.983  1   76.81  ? 234 PRO C O   1 
ATOM   8588 C CB  . PRO D 2 238 ? -69.813 12.102  42.898  1   79.48  ? 234 PRO C CB  1 
ATOM   8589 C CG  . PRO D 2 238 ? -68.491 12.621  43.403  1   75.53  ? 234 PRO C CG  1 
ATOM   8590 C CD  . PRO D 2 238 ? -67.518 11.478  43.247  1   73.35  ? 234 PRO C CD  1 
ATOM   8591 N N   . ASP D 2 239 ? -70.483 11.796  39.726  1   82.03  ? 235 ASP C N   1 
ATOM   8592 C CA  . ASP D 2 239 ? -70.475 12.34   38.339  1   78.27  ? 235 ASP C CA  1 
ATOM   8593 C C   . ASP D 2 239 ? -70.55  13.863  38.348  1   74.34  ? 235 ASP C C   1 
ATOM   8594 O O   . ASP D 2 239 ? -71.666 14.398  38.471  1   71.64  ? 235 ASP C O   1 
ATOM   8595 C CB  . ASP D 2 239 ? -71.568 11.743  37.472  1   81.01  ? 235 ASP C CB  1 
ATOM   8596 C CG  . ASP D 2 239 ? -71.771 12.404  36.118  1   84.19  ? 235 ASP C CG  1 
ATOM   8597 O OD1 . ASP D 2 239 ? -70.764 12.641  35.425  1   79.02  ? 235 ASP C OD1 1 
ATOM   8598 O OD2 . ASP D 2 239 ? -72.937 12.679  35.774  1   90.53  ? 235 ASP C OD2 1 
ATOM   8599 N N   . TYR D 2 240 ? -69.406 14.522  38.238  1   75.25  ? 236 TYR C N   1 
ATOM   8600 C CA  . TYR D 2 240 ? -69.314 15.975  38.12   1   80.24  ? 236 TYR C CA  1 
ATOM   8601 C C   . TYR D 2 240 ? -68.214 16.369  37.12   1   80.15  ? 236 TYR C C   1 
ATOM   8602 O O   . TYR D 2 240 ? -67.05  15.991  37.273  1   75.93  ? 236 TYR C O   1 
ATOM   8603 C CB  . TYR D 2 240 ? -68.99  16.644  39.468  1   78.05  ? 236 TYR C CB  1 
ATOM   8604 C CG  . TYR D 2 240 ? -70.016 16.493  40.581  1   77.47  ? 236 TYR C CG  1 
ATOM   8605 C CD1 . TYR D 2 240 ? -71.2   17.221  40.552  1   82.39  ? 236 TYR C CD1 1 
ATOM   8606 C CD2 . TYR D 2 240 ? -69.795 15.653  41.669  1   76.44  ? 236 TYR C CD2 1 
ATOM   8607 C CE1 . TYR D 2 240 ? -72.153 17.084  41.554  1   84.68  ? 236 TYR C CE1 1 
ATOM   8608 C CE2 . TYR D 2 240 ? -70.737 15.516  42.682  1   77.11  ? 236 TYR C CE2 1 
ATOM   8609 C CZ  . TYR D 2 240 ? -71.922 16.232  42.624  1   79.93  ? 236 TYR C CZ  1 
ATOM   8610 O OH  . TYR D 2 240 ? -72.859 16.119  43.612  1   79.94  ? 236 TYR C OH  1 
ATOM   8611 N N   . LYS D 2 241 ? -68.57  17.158  36.097  1   80.74  ? 237 LYS C N   1 
ATOM   8612 C CA  . LYS D 2 241 ? -67.608 17.744  35.171  1   80.71  ? 237 LYS C CA  1 
ATOM   8613 C C   . LYS D 2 241 ? -67.507 19.241  35.484  1   80.35  ? 237 LYS C C   1 
ATOM   8614 O O   . LYS D 2 241 ? -68.533 19.875  35.717  1   85.17  ? 237 LYS C O   1 
ATOM   8615 C CB  . LYS D 2 241 ? -68.113 17.463  33.745  1   82.96  ? 237 LYS C CB  1 
ATOM   8616 C CG  . LYS D 2 241 ? -67.421 18.168  32.577  1   85.26  ? 237 LYS C CG  1 
ATOM   8617 C CD  . LYS D 2 241 ? -68.345 18.383  31.377  1   85.51  ? 237 LYS C CD  1 
ATOM   8618 C CE  . LYS D 2 241 ? -68.746 17.131  30.644  1   87.75  ? 237 LYS C CE  1 
ATOM   8619 N NZ  . LYS D 2 241 ? -69.65  17.391  29.519  1   87.71  ? 237 LYS C NZ  1 
ATOM   8620 N N   . PRO D 2 242 ? -66.303 19.865  35.531  1   74.53  ? 238 PRO C N   1 
ATOM   8621 C CA  . PRO D 2 242 ? -66.187 21.3    35.823  1   75.65  ? 238 PRO C CA  1 
ATOM   8622 C C   . PRO D 2 242 ? -66.609 22.295  34.733  1   77.54  ? 238 PRO C C   1 
ATOM   8623 O O   . PRO D 2 242 ? -66.634 21.934  33.558  1   76.2   ? 238 PRO C O   1 
ATOM   8624 C CB  . PRO D 2 242 ? -64.702 21.481  36.232  1   70.41  ? 238 PRO C CB  1 
ATOM   8625 C CG  . PRO D 2 242 ? -64.099 20.102  36.255  1   67.75  ? 238 PRO C CG  1 
ATOM   8626 C CD  . PRO D 2 242 ? -64.991 19.227  35.375  1   71.07  ? 238 PRO C CD  1 
ATOM   8627 N N   . SER D 2 243 ? -66.839 23.526  35.199  1   78.87  ? 239 SER C N   1 
ATOM   8628 C CA  . SER D 2 243 ? -67.132 24.646  34.281  1   81.11  ? 239 SER C CA  1 
ATOM   8629 C C   . SER D 2 243 ? -66.009 25.669  34.483  1   85.61  ? 239 SER C C   1 
ATOM   8630 O O   . SER D 2 243 ? -65.428 25.69   35.591  1   84.88  ? 239 SER C O   1 
ATOM   8631 C CB  . SER D 2 243 ? -68.48  25.246  34.559  1   80.63  ? 239 SER C CB  1 
ATOM   8632 O OG  . SER D 2 243 ? -68.419 26.12   35.677  1   83     ? 239 SER C OG  1 
ATOM   8633 N N   . PHE D 2 244 ? -65.715 26.477  33.474  1   86.88  ? 240 PHE C N   1 
ATOM   8634 C CA  . PHE D 2 244 ? -64.64  27.472  33.483  1   84.07  ? 240 PHE C CA  1 
ATOM   8635 C C   . PHE D 2 244 ? -64.975 28.75   32.698  1   86.34  ? 240 PHE C C   1 
ATOM   8636 O O   . PHE D 2 244 ? -64.1   29.286  32.011  1   87.72  ? 240 PHE C O   1 
ATOM   8637 C CB  . PHE D 2 244 ? -63.392 26.907  32.797  1   79.71  ? 240 PHE C CB  1 
ATOM   8638 C CG  . PHE D 2 244 ? -62.915 25.541  33.267  1   76.61  ? 240 PHE C CG  1 
ATOM   8639 C CD1 . PHE D 2 244 ? -62.234 25.405  34.485  1   68.69  ? 240 PHE C CD1 1 
ATOM   8640 C CD2 . PHE D 2 244 ? -63.139 24.409  32.478  1   73.75  ? 240 PHE C CD2 1 
ATOM   8641 C CE1 . PHE D 2 244 ? -61.807 24.16   34.911  1   66.19  ? 240 PHE C CE1 1 
ATOM   8642 C CE2 . PHE D 2 244 ? -62.698 23.163  32.899  1   71.28  ? 240 PHE C CE2 1 
ATOM   8643 C CZ  . PHE D 2 244 ? -62.037 23.044  34.117  1   70.92  ? 240 PHE C CZ  1 
ATOM   8644 N N   . PRO D 2 245 ? -66.194 29.339  32.804  1   85.84  ? 241 PRO C N   1 
ATOM   8645 C CA  . PRO D 2 245 ? -66.619 30.364  31.833  1   85.45  ? 241 PRO C CA  1 
ATOM   8646 C C   . PRO D 2 245 ? -65.7   31.577  31.605  1   79.46  ? 241 PRO C C   1 
ATOM   8647 O O   . PRO D 2 245 ? -65.077 32.048  32.583  1   73.85  ? 241 PRO C O   1 
ATOM   8648 C CB  . PRO D 2 245 ? -68.023 30.77   32.31   1   86.95  ? 241 PRO C CB  1 
ATOM   8649 C CG  . PRO D 2 245 ? -68.464 29.62   33.198  1   84.14  ? 241 PRO C CG  1 
ATOM   8650 C CD  . PRO D 2 245 ? -67.201 29.069  33.85   1   81.08  ? 241 PRO C CD  1 
ATOM   8651 N N   . PRO D 2 258 ? -59.426 33.45   26.974  1   74.91  ? 254 PRO C N   1 
ATOM   8652 C CA  . PRO D 2 258 ? -59.012 33.472  25.568  1   76.43  ? 254 PRO C CA  1 
ATOM   8653 C C   . PRO D 2 258 ? -59.039 32.106  24.861  1   83.43  ? 254 PRO C C   1 
ATOM   8654 O O   . PRO D 2 258 ? -58.191 31.8    24.011  1   85.36  ? 254 PRO C O   1 
ATOM   8655 C CB  . PRO D 2 258 ? -57.578 34.054  25.684  1   73.19  ? 254 PRO C CB  1 
ATOM   8656 C CG  . PRO D 2 258 ? -57.084 33.63   27.074  1   68.38  ? 254 PRO C CG  1 
ATOM   8657 C CD  . PRO D 2 258 ? -58.332 33.562  27.962  1   69.34  ? 254 PRO C CD  1 
ATOM   8658 N N   . LEU D 2 259 ? -60.025 31.267  25.224  1   82.48  ? 255 LEU C N   1 
ATOM   8659 C CA  . LEU D 2 259 ? -60.129 29.889  24.76   1   74.11  ? 255 LEU C CA  1 
ATOM   8660 C C   . LEU D 2 259 ? -61.5   29.694  24.116  1   73.89  ? 255 LEU C C   1 
ATOM   8661 O O   . LEU D 2 259 ? -62.51  29.823  24.807  1   73.07  ? 255 LEU C O   1 
ATOM   8662 C CB  . LEU D 2 259 ? -59.977 28.989  25.986  1   68.44  ? 255 LEU C CB  1 
ATOM   8663 C CG  . LEU D 2 259 ? -60.124 27.48   25.753  1   62.58  ? 255 LEU C CG  1 
ATOM   8664 C CD1 . LEU D 2 259 ? -59.058 26.897  24.826  1   57.43  ? 255 LEU C CD1 1 
ATOM   8665 C CD2 . LEU D 2 259 ? -60.211 26.707  27.055  1   61.6   ? 255 LEU C CD2 1 
ATOM   8666 N N   . ASP D 2 260 ? -61.525 29.37   22.812  1   74.72  ? 256 ASP C N   1 
ATOM   8667 C CA  . ASP D 2 260 ? -62.767 29.232  22.052  1   78.8   ? 256 ASP C CA  1 
ATOM   8668 C C   . ASP D 2 260 ? -63.601 28.099  22.643  1   80.48  ? 256 ASP C C   1 
ATOM   8669 O O   . ASP D 2 260 ? -63.043 27.22   23.309  1   82.37  ? 256 ASP C O   1 
ATOM   8670 C CB  . ASP D 2 260 ? -62.526 28.994  20.567  1   78.97  ? 256 ASP C CB  1 
ATOM   8671 C CG  . ASP D 2 260 ? -61.546 27.873  20.244  1   77.99  ? 256 ASP C CG  1 
ATOM   8672 O OD1 . ASP D 2 260 ? -60.352 28.034  20.572  1   76.01  ? 256 ASP C OD1 1 
ATOM   8673 O OD2 . ASP D 2 260 ? -61.981 26.847  19.682  1   75.34  ? 256 ASP C OD2 1 
ATOM   8674 N N   . GLU D 2 261 ? -64.922 28.13   22.375  1   81.66  ? 257 GLU C N   1 
ATOM   8675 C CA  . GLU D 2 261 ? -65.92  27.241  22.972  1   79.67  ? 257 GLU C CA  1 
ATOM   8676 C C   . GLU D 2 261 ? -65.449 25.777  22.975  1   72.17  ? 257 GLU C C   1 
ATOM   8677 O O   . GLU D 2 261 ? -65.703 25.014  23.92   1   68.55  ? 257 GLU C O   1 
ATOM   8678 C CB  . GLU D 2 261 ? -67.265 27.397  22.251  1   84.04  ? 257 GLU C CB  1 
ATOM   8679 C CG  . GLU D 2 261 ? -68.275 26.338  22.686  1   87.97  ? 257 GLU C CG  1 
ATOM   8680 C CD  . GLU D 2 261 ? -69.544 26.155  21.872  1   91.4   ? 257 GLU C CD  1 
ATOM   8681 O OE1 . GLU D 2 261 ? -70.601 26.432  22.461  1   93.27  ? 257 GLU C OE1 1 
ATOM   8682 O OE2 . GLU D 2 261 ? -69.498 25.726  20.699  1   89.85  ? 257 GLU C OE2 1 
ATOM   8683 N N   . ASP D 2 262 ? -64.784 25.404  21.876  1   67.26  ? 258 ASP C N   1 
ATOM   8684 C CA  . ASP D 2 262 ? -64.217 24.091  21.663  1   63.05  ? 258 ASP C CA  1 
ATOM   8685 C C   . ASP D 2 262 ? -63.132 23.817  22.69   1   59.66  ? 258 ASP C C   1 
ATOM   8686 O O   . ASP D 2 262 ? -63.104 22.739  23.288  1   58.82  ? 258 ASP C O   1 
ATOM   8687 C CB  . ASP D 2 262 ? -63.584 24.01   20.288  1   64.64  ? 258 ASP C CB  1 
ATOM   8688 C CG  . ASP D 2 262 ? -64.538 23.627  19.169  1   67.77  ? 258 ASP C CG  1 
ATOM   8689 O OD1 . ASP D 2 262 ? -65.679 23.24   19.502  1   69.01  ? 258 ASP C OD1 1 
ATOM   8690 O OD2 . ASP D 2 262 ? -64.126 23.708  17.984  1   67.56  ? 258 ASP C OD2 1 
ATOM   8691 N N   . GLY D 2 263 ? -62.214 24.788  22.81   1   57.76  ? 259 GLY C N   1 
ATOM   8692 C CA  . GLY D 2 263 ? -61.119 24.723  23.759  1   53.9   ? 259 GLY C CA  1 
ATOM   8693 C C   . GLY D 2 263 ? -61.632 24.401  25.157  1   53.41  ? 259 GLY C C   1 
ATOM   8694 O O   . GLY D 2 263 ? -61.052 23.576  25.863  1   52.74  ? 259 GLY C O   1 
ATOM   8695 N N   . ARG D 2 264 ? -62.726 25.059  25.537  1   55.54  ? 260 ARG C N   1 
ATOM   8696 C CA  . ARG D 2 264 ? -63.247 24.971  26.889  1   57.29  ? 260 ARG C CA  1 
ATOM   8697 C C   . ARG D 2 264 ? -63.863 23.596  27.12   1   57.4   ? 260 ARG C C   1 
ATOM   8698 O O   . ARG D 2 264 ? -63.795 23.056  28.228  1   55.82  ? 260 ARG C O   1 
ATOM   8699 C CB  . ARG D 2 264 ? -64.196 26.135  27.202  1   60.19  ? 260 ARG C CB  1 
ATOM   8700 C CG  . ARG D 2 264 ? -63.445 27.444  27.398  1   61.84  ? 260 ARG C CG  1 
ATOM   8701 C CD  . ARG D 2 264 ? -64.283 28.611  27.899  1   66.05  ? 260 ARG C CD  1 
ATOM   8702 N NE  . ARG D 2 264 ? -64.824 29.429  26.81   1   70.75  ? 260 ARG C NE  1 
ATOM   8703 C CZ  . ARG D 2 264 ? -65.943 29.191  26.125  1   75.25  ? 260 ARG C CZ  1 
ATOM   8704 N NH1 . ARG D 2 264 ? -66.743 28.203  26.494  1   75.63  ? 260 ARG C NH1 1 
ATOM   8705 N NH2 . ARG D 2 264 ? -66.271 29.963  25.093  1   76.52  ? 260 ARG C NH2 1 
ATOM   8706 N N   . SER D 2 265 ? -64.469 23.051  26.062  1   60.43  ? 261 SER C N   1 
ATOM   8707 C CA  . SER D 2 265 ? -65.044 21.717  26.116  1   62.43  ? 261 SER C CA  1 
ATOM   8708 C C   . SER D 2 265 ? -63.941 20.679  26.344  1   59.91  ? 261 SER C C   1 
ATOM   8709 O O   . SER D 2 265 ? -63.951 19.957  27.346  1   58.18  ? 261 SER C O   1 
ATOM   8710 C CB  . SER D 2 265 ? -65.834 21.428  24.866  1   64.2   ? 261 SER C CB  1 
ATOM   8711 O OG  . SER D 2 265 ? -66.508 20.185  24.999  1   65.91  ? 261 SER C OG  1 
ATOM   8712 N N   . LEU D 2 266 ? -62.982 20.633  25.408  1   58.33  ? 262 LEU C N   1 
ATOM   8713 C CA  . LEU D 2 266 ? -61.867 19.705  25.486  1   55.09  ? 262 LEU C CA  1 
ATOM   8714 C C   . LEU D 2 266 ? -61.35  19.683  26.918  1   52.72  ? 262 LEU C C   1 
ATOM   8715 O O   . LEU D 2 266 ? -61.202 18.619  27.506  1   51.95  ? 262 LEU C O   1 
ATOM   8716 C CB  . LEU D 2 266 ? -60.761 20.099  24.505  1   53.93  ? 262 LEU C CB  1 
ATOM   8717 C CG  . LEU D 2 266 ? -59.563 19.145  24.414  1   51.03  ? 262 LEU C CG  1 
ATOM   8718 C CD1 . LEU D 2 266 ? -60.04  17.724  24.158  1   52.27  ? 262 LEU C CD1 1 
ATOM   8719 C CD2 . LEU D 2 266 ? -58.594 19.584  23.321  1   49.49  ? 262 LEU C CD2 1 
ATOM   8720 N N   . LEU D 2 267 ? -61.117 20.879  27.463  1   51.76  ? 263 LEU C N   1 
ATOM   8721 C CA  . LEU D 2 267 ? -60.527 21.043  28.776  1   50.07  ? 263 LEU C CA  1 
ATOM   8722 C C   . LEU D 2 267 ? -61.36  20.289  29.822  1   52.49  ? 263 LEU C C   1 
ATOM   8723 O O   . LEU D 2 267 ? -60.82  19.537  30.642  1   51.69  ? 263 LEU C O   1 
ATOM   8724 C CB  . LEU D 2 267 ? -60.409 22.543  29.062  1   48.28  ? 263 LEU C CB  1 
ATOM   8725 C CG  . LEU D 2 267 ? -59.784 22.923  30.411  1   45.91  ? 263 LEU C CG  1 
ATOM   8726 C CD1 . LEU D 2 267 ? -58.306 22.621  30.441  1   44.03  ? 263 LEU C CD1 1 
ATOM   8727 C CD2 . LEU D 2 267 ? -60.001 24.365  30.768  1   46.65  ? 263 LEU C CD2 1 
ATOM   8728 N N   . SER D 2 268 ? -62.684 20.499  29.8    1   54.25  ? 264 SER C N   1 
ATOM   8729 C CA  . SER D 2 268 ? -63.534 19.99   30.867  1   54.09  ? 264 SER C CA  1 
ATOM   8730 C C   . SER D 2 268 ? -63.787 18.498  30.671  1   53.77  ? 264 SER C C   1 
ATOM   8731 O O   . SER D 2 268 ? -64.219 17.81   31.594  1   52.68  ? 264 SER C O   1 
ATOM   8732 C CB  . SER D 2 268 ? -64.807 20.771  30.978  1   55.5   ? 264 SER C CB  1 
ATOM   8733 O OG  . SER D 2 268 ? -65.308 21.019  29.675  1   60.28  ? 264 SER C OG  1 
ATOM   8734 N N   . GLN D 2 269 ? -63.511 18.021  29.454  1   54.7   ? 265 GLN C N   1 
ATOM   8735 C CA  . GLN D 2 269 ? -63.528 16.595  29.166  1   56.63  ? 265 GLN C CA  1 
ATOM   8736 C C   . GLN D 2 269 ? -62.269 15.96   29.741  1   55.32  ? 265 GLN C C   1 
ATOM   8737 O O   . GLN D 2 269 ? -62.338 14.865  30.283  1   58.39  ? 265 GLN C O   1 
ATOM   8738 C CB  . GLN D 2 269 ? -63.726 16.32   27.679  1   55.78  ? 265 GLN C CB  1 
ATOM   8739 C CG  . GLN D 2 269 ? -65.13  16.698  27.228  1   60.13  ? 265 GLN C CG  1 
ATOM   8740 C CD  . GLN D 2 269 ? -65.292 16.707  25.726  1   62.6   ? 265 GLN C CD  1 
ATOM   8741 O OE1 . GLN D 2 269 ? -65.344 17.768  25.091  1   63.8   ? 265 GLN C OE1 1 
ATOM   8742 N NE2 . GLN D 2 269 ? -65.346 15.516  25.141  1   62.64  ? 265 GLN C NE2 1 
ATOM   8743 N N   . MET D 2 270 ? -61.14  16.673  29.644  1   52.69  ? 266 MET C N   1 
ATOM   8744 C CA  . MET D 2 270 ? -59.861 16.228  30.173  1   47.56  ? 266 MET C CA  1 
ATOM   8745 C C   . MET D 2 270 ? -59.87  16.317  31.692  1   49.46  ? 266 MET C C   1 
ATOM   8746 O O   . MET D 2 270 ? -59.121 15.589  32.341  1   51.92  ? 266 MET C O   1 
ATOM   8747 C CB  . MET D 2 270 ? -58.695 17.057  29.623  1   44.43  ? 266 MET C CB  1 
ATOM   8748 C CG  . MET D 2 270 ? -58.49  16.898  28.124  1   43.7   ? 266 MET C CG  1 
ATOM   8749 S SD  . MET D 2 270 ? -57.191 17.937  27.432  1   41.46  ? 266 MET C SD  1 
ATOM   8750 C CE  . MET D 2 270 ? -55.753 16.914  27.767  1   37.02  ? 266 MET C CE  1 
ATOM   8751 N N   . LEU D 2 271 ? -60.734 17.18   32.248  1   52.13  ? 267 LEU C N   1 
ATOM   8752 C CA  . LEU D 2 271 ? -60.796 17.402  33.689  1   51.48  ? 267 LEU C CA  1 
ATOM   8753 C C   . LEU D 2 271 ? -62.104 16.896  34.304  1   53.4   ? 267 LEU C C   1 
ATOM   8754 O O   . LEU D 2 271 ? -62.55  17.458  35.294  1   54.98  ? 267 LEU C O   1 
ATOM   8755 C CB  . LEU D 2 271 ? -60.59  18.895  33.934  1   49.29  ? 267 LEU C CB  1 
ATOM   8756 C CG  . LEU D 2 271 ? -59.195 19.409  33.579  1   47.61  ? 267 LEU C CG  1 
ATOM   8757 C CD1 . LEU D 2 271 ? -59.108 20.917  33.742  1   47.65  ? 267 LEU C CD1 1 
ATOM   8758 C CD2 . LEU D 2 271 ? -58.134 18.691  34.413  1   45.68  ? 267 LEU C CD2 1 
ATOM   8759 N N   . HIS D 2 272 ? -62.701 15.829  33.745  1   53.78  ? 268 HIS C N   1 
ATOM   8760 C CA  . HIS D 2 272 ? -63.977 15.318  34.227  1   54.42  ? 268 HIS C CA  1 
ATOM   8761 C C   . HIS D 2 272 ? -63.686 14.592  35.526  1   53.14  ? 268 HIS C C   1 
ATOM   8762 O O   . HIS D 2 272 ? -62.673 13.901  35.609  1   54.54  ? 268 HIS C O   1 
ATOM   8763 C CB  . HIS D 2 272 ? -64.621 14.355  33.216  1   56.41  ? 268 HIS C CB  1 
ATOM   8764 C CG  . HIS D 2 272 ? -66.097 14.083  33.381  1   57.67  ? 268 HIS C CG  1 
ATOM   8765 N ND1 . HIS D 2 272 ? -66.652 13.48   34.49   1   57.08  ? 268 HIS C ND1 1 
ATOM   8766 C CD2 . HIS D 2 272 ? -67.137 14.365  32.572  1   59.05  ? 268 HIS C CD2 1 
ATOM   8767 C CE1 . HIS D 2 272 ? -67.97  13.405  34.347  1   58.35  ? 268 HIS C CE1 1 
ATOM   8768 N NE2 . HIS D 2 272 ? -68.286 13.936  33.195  1   59.54  ? 268 HIS C NE2 1 
ATOM   8769 N N   . TYR D 2 273 ? -64.556 14.778  36.523  1   53.31  ? 269 TYR C N   1 
ATOM   8770 C CA  . TYR D 2 273 ? -64.255 14.308  37.861  1   54.84  ? 269 TYR C CA  1 
ATOM   8771 C C   . TYR D 2 273 ? -64.313 12.782  37.923  1   55.91  ? 269 TYR C C   1 
ATOM   8772 O O   . TYR D 2 273 ? -63.528 12.173  38.65   1   53.49  ? 269 TYR C O   1 
ATOM   8773 C CB  . TYR D 2 273 ? -65.14  15.019  38.886  1   58.01  ? 269 TYR C CB  1 
ATOM   8774 C CG  . TYR D 2 273 ? -64.73  14.782  40.335  1   60.96  ? 269 TYR C CG  1 
ATOM   8775 C CD1 . TYR D 2 273 ? -63.678 15.499  40.897  1   59.34  ? 269 TYR C CD1 1 
ATOM   8776 C CD2 . TYR D 2 273 ? -65.395 13.856  41.139  1   62.47  ? 269 TYR C CD2 1 
ATOM   8777 C CE1 . TYR D 2 273 ? -63.298 15.302  42.212  1   59.02  ? 269 TYR C CE1 1 
ATOM   8778 C CE2 . TYR D 2 273 ? -65.032 13.66   42.459  1   61.55  ? 269 TYR C CE2 1 
ATOM   8779 C CZ  . TYR D 2 273 ? -63.975 14.379  42.992  1   60.69  ? 269 TYR C CZ  1 
ATOM   8780 O OH  . TYR D 2 273 ? -63.613 14.161  44.291  1   60.77  ? 269 TYR C OH  1 
ATOM   8781 N N   . ASP D 2 274 ? -65.26  12.185  37.179  1   58.47  ? 270 ASP C N   1 
ATOM   8782 C CA  . ASP D 2 274 ? -65.362 10.74   37.048  1   59.5   ? 270 ASP C CA  1 
ATOM   8783 C C   . ASP D 2 274 ? -64.322 10.264  36.028  1   54.75  ? 270 ASP C C   1 
ATOM   8784 O O   . ASP D 2 274 ? -64.41  10.655  34.867  1   54.12  ? 270 ASP C O   1 
ATOM   8785 C CB  . ASP D 2 274 ? -66.77  10.297  36.675  1   65.16  ? 270 ASP C CB  1 
ATOM   8786 C CG  . ASP D 2 274 ? -67.025 8.793   36.744  1   71.91  ? 270 ASP C CG  1 
ATOM   8787 O OD1 . ASP D 2 274 ? -67.274 8.295   37.867  1   78.74  ? 270 ASP C OD1 1 
ATOM   8788 O OD2 . ASP D 2 274 ? -66.943 8.112   35.683  1   70.48  ? 270 ASP C OD2 1 
ATOM   8789 N N   . PRO D 2 275 ? -63.331 9.418   36.43   1   49.05  ? 271 PRO C N   1 
ATOM   8790 C CA  . PRO D 2 275 ? -62.32  8.874   35.518  1   46.27  ? 271 PRO C CA  1 
ATOM   8791 C C   . PRO D 2 275 ? -62.82  8.067   34.325  1   47.37  ? 271 PRO C C   1 
ATOM   8792 O O   . PRO D 2 275 ? -62.143 7.994   33.303  1   45.59  ? 271 PRO C O   1 
ATOM   8793 C CB  . PRO D 2 275 ? -61.49  7.949   36.413  1   45.2   ? 271 PRO C CB  1 
ATOM   8794 C CG  . PRO D 2 275 ? -61.705 8.447   37.806  1   44.55  ? 271 PRO C CG  1 
ATOM   8795 C CD  . PRO D 2 275 ? -63.124 8.953   37.81   1   47.34  ? 271 PRO C CD  1 
ATOM   8796 N N   . ASN D 2 276 ? -63.984 7.43    34.476  1   51.48  ? 272 ASN C N   1 
ATOM   8797 C CA  . ASN D 2 276 ? -64.516 6.582   33.418  1   55.07  ? 272 ASN C CA  1 
ATOM   8798 C C   . ASN D 2 276 ? -65.068 7.438   32.289  1   55.53  ? 272 ASN C C   1 
ATOM   8799 O O   . ASN D 2 276 ? -65.192 6.929   31.187  1   60.48  ? 272 ASN C O   1 
ATOM   8800 C CB  . ASN D 2 276 ? -65.629 5.628   33.854  1   58.28  ? 272 ASN C CB  1 
ATOM   8801 C CG  . ASN D 2 276 ? -65.288 4.835   35.096  1   60.86  ? 272 ASN C CG  1 
ATOM   8802 O OD1 . ASN D 2 276 ? -64.127 4.452   35.296  1   61.26  ? 272 ASN C OD1 1 
ATOM   8803 N ND2 . ASN D 2 276 ? -66.272 4.616   35.961  1   62.22  ? 272 ASN C ND2 1 
ATOM   8804 N N   . LYS D 2 277 ? -65.396 8.71    32.568  1   53.36  ? 273 LYS C N   1 
ATOM   8805 C CA  . LYS D 2 277 ? -66.026 9.575   31.583  1   52.33  ? 273 LYS C CA  1 
ATOM   8806 C C   . LYS D 2 277 ? -65.029 10.581  31.027  1   50.48  ? 273 LYS C C   1 
ATOM   8807 O O   . LYS D 2 277 ? -65.374 11.291  30.085  1   52.48  ? 273 LYS C O   1 
ATOM   8808 C CB  . LYS D 2 277 ? -67.184 10.408  32.139  1   53.23  ? 273 LYS C CB  1 
ATOM   8809 C CG  . LYS D 2 277 ? -67.928 9.755   33.285  1   54.55  ? 273 LYS C CG  1 
ATOM   8810 C CD  . LYS D 2 277 ? -69.365 10.22   33.429  1   55.86  ? 273 LYS C CD  1 
ATOM   8811 C CE  . LYS D 2 277 ? -70.244 9.444   32.511  1   58.62  ? 273 LYS C CE  1 
ATOM   8812 N NZ  . LYS D 2 277 ? -71.619 9.934   32.638  1   63.14  ? 273 LYS C NZ  1 
ATOM   8813 N N   . ARG D 2 278 ? -63.843 10.679  31.654  1   46.89  ? 274 ARG C N   1 
ATOM   8814 C CA  . ARG D 2 278 ? -62.777 11.579  31.232  1   44.32  ? 274 ARG C CA  1 
ATOM   8815 C C   . ARG D 2 278 ? -62.297 11.16   29.846  1   45.2   ? 274 ARG C C   1 
ATOM   8816 O O   . ARG D 2 278 ? -62.188 9.971   29.571  1   47.52  ? 274 ARG C O   1 
ATOM   8817 C CB  . ARG D 2 278 ? -61.633 11.536  32.252  1   41.42  ? 274 ARG C CB  1 
ATOM   8818 C CG  . ARG D 2 278 ? -60.605 12.657  32.157  1   39.2   ? 274 ARG C CG  1 
ATOM   8819 C CD  . ARG D 2 278 ? -59.645 12.594  33.325  1   37.54  ? 274 ARG C CD  1 
ATOM   8820 N NE  . ARG D 2 278 ? -60.358 12.595  34.609  1   38.92  ? 274 ARG C NE  1 
ATOM   8821 C CZ  . ARG D 2 278 ? -59.875 12.074  35.747  1   38.91  ? 274 ARG C CZ  1 
ATOM   8822 N NH1 . ARG D 2 278 ? -58.655 11.551  35.797  1   37.24  ? 274 ARG C NH1 1 
ATOM   8823 N NH2 . ARG D 2 278 ? -60.613 12.071  36.845  1   39.49  ? 274 ARG C NH2 1 
ATOM   8824 N N   . ILE D 2 279 ? -61.974 12.129  28.987  1   45.52  ? 275 ILE C N   1 
ATOM   8825 C CA  . ILE D 2 279 ? -61.648 11.803  27.608  1   47.69  ? 275 ILE C CA  1 
ATOM   8826 C C   . ILE D 2 279 ? -60.393 10.929  27.57   1   48.46  ? 275 ILE C C   1 
ATOM   8827 O O   . ILE D 2 279 ? -59.531 11.018  28.439  1   49.21  ? 275 ILE C O   1 
ATOM   8828 C CB  . ILE D 2 279 ? -61.543 13.067  26.733  1   46.8   ? 275 ILE C CB  1 
ATOM   8829 C CG1 . ILE D 2 279 ? -61.831 12.753  25.263  1   47.86  ? 275 ILE C CG1 1 
ATOM   8830 C CG2 . ILE D 2 279 ? -60.21  13.789  26.909  1   43.43  ? 275 ILE C CG2 1 
ATOM   8831 C CD1 . ILE D 2 279 ? -62.152 13.979  24.428  1   48.58  ? 275 ILE C CD1 1 
ATOM   8832 N N   . SER D 2 280 ? -60.308 10.055  26.572  1   51.2   ? 276 SER C N   1 
ATOM   8833 C CA  . SER D 2 280 ? -59.065 9.343   26.32   1   53.13  ? 276 SER C CA  1 
ATOM   8834 C C   . SER D 2 280 ? -58.164 10.227  25.455  1   51.85  ? 276 SER C C   1 
ATOM   8835 O O   . SER D 2 280 ? -58.661 11.123  24.773  1   51.99  ? 276 SER C O   1 
ATOM   8836 C CB  . SER D 2 280 ? -59.327 8       25.655  1   57.75  ? 276 SER C CB  1 
ATOM   8837 O OG  . SER D 2 280 ? -59.752 8.17    24.303  1   62.72  ? 276 SER C OG  1 
ATOM   8838 N N   . ALA D 2 281 ? -56.847 9.975   25.488  1   49.05  ? 277 ALA C N   1 
ATOM   8839 C CA  . ALA D 2 281 ? -55.933 10.695  24.617  1   47.76  ? 277 ALA C CA  1 
ATOM   8840 C C   . ALA D 2 281 ? -56.367 10.535  23.158  1   49.39  ? 277 ALA C C   1 
ATOM   8841 O O   . ALA D 2 281 ? -56.457 11.525  22.43   1   48.86  ? 277 ALA C O   1 
ATOM   8842 C CB  . ALA D 2 281 ? -54.521 10.217  24.847  1   45.82  ? 277 ALA C CB  1 
ATOM   8843 N N   . LYS D 2 282 ? -56.648 9.28    22.757  1   49.09  ? 278 LYS C N   1 
ATOM   8844 C CA  . LYS D 2 282 ? -57.116 8.947   21.423  1   49.94  ? 278 LYS C CA  1 
ATOM   8845 C C   . LYS D 2 282 ? -58.314 9.801   21.042  1   51.92  ? 278 LYS C C   1 
ATOM   8846 O O   . LYS D 2 282 ? -58.341 10.375  19.954  1   53.91  ? 278 LYS C O   1 
ATOM   8847 C CB  . LYS D 2 282 ? -57.62  7.507   21.31   1   51.26  ? 278 LYS C CB  1 
ATOM   8848 C CG  . LYS D 2 282 ? -56.673 6.541   20.635  1   51.95  ? 278 LYS C CG  1 
ATOM   8849 C CD  . LYS D 2 282 ? -57.357 5.191   20.421  1   53.93  ? 278 LYS C CD  1 
ATOM   8850 C CE  . LYS D 2 282 ? -56.432 4.016   20.558  1   50.56  ? 278 LYS C CE  1 
ATOM   8851 N NZ  . LYS D 2 282 ? -56.949 2.861   19.831  1   50.61  ? 278 LYS C NZ  1 
ATOM   8852 N N   . ALA D 2 283 ? -59.324 9.814   21.914  1   52.87  ? 279 ALA C N   1 
ATOM   8853 C CA  . ALA D 2 283 ? -60.518 10.615  21.688  1   58.22  ? 279 ALA C CA  1 
ATOM   8854 C C   . ALA D 2 283 ? -60.161 12.096  21.497  1   59.27  ? 279 ALA C C   1 
ATOM   8855 O O   . ALA D 2 283 ? -60.546 12.713  20.502  1   61     ? 279 ALA C O   1 
ATOM   8856 C CB  . ALA D 2 283 ? -61.488 10.388  22.822  1   58.23  ? 279 ALA C CB  1 
ATOM   8857 N N   . ALA D 2 284 ? -59.403 12.656  22.449  1   59.01  ? 280 ALA C N   1 
ATOM   8858 C CA  . ALA D 2 284 ? -59.01  14.054  22.417  1   57.87  ? 280 ALA C CA  1 
ATOM   8859 C C   . ALA D 2 284 ? -58.354 14.404  21.082  1   57.42  ? 280 ALA C C   1 
ATOM   8860 O O   . ALA D 2 284 ? -58.563 15.494  20.564  1   61.33  ? 280 ALA C O   1 
ATOM   8861 C CB  . ALA D 2 284 ? -58.102 14.355  23.589  1   55.47  ? 280 ALA C CB  1 
ATOM   8862 N N   . LEU D 2 285 ? -57.589 13.47   20.512  1   53.87  ? 281 LEU C N   1 
ATOM   8863 C CA  . LEU D 2 285 ? -56.879 13.727  19.271  1   53.89  ? 281 LEU C CA  1 
ATOM   8864 C C   . LEU D 2 285 ? -57.834 14.066  18.129  1   58.5   ? 281 LEU C C   1 
ATOM   8865 O O   . LEU D 2 285 ? -57.42  14.724  17.166  1   60.41  ? 281 LEU C O   1 
ATOM   8866 C CB  . LEU D 2 285 ? -56.001 12.536  18.91   1   52.66  ? 281 LEU C CB  1 
ATOM   8867 C CG  . LEU D 2 285 ? -54.648 12.495  19.62   1   52.13  ? 281 LEU C CG  1 
ATOM   8868 C CD1 . LEU D 2 285 ? -53.964 11.153  19.409  1   50.57  ? 281 LEU C CD1 1 
ATOM   8869 C CD2 . LEU D 2 285 ? -53.77  13.663  19.165  1   51.35  ? 281 LEU C CD2 1 
ATOM   8870 N N   . ALA D 2 286 ? -59.092 13.603  18.235  1   59.17  ? 282 ALA C N   1 
ATOM   8871 C CA  . ALA D 2 286 ? -60.091 13.829  17.195  1   61.23  ? 282 ALA C CA  1 
ATOM   8872 C C   . ALA D 2 286 ? -61.026 14.991  17.535  1   62.72  ? 282 ALA C C   1 
ATOM   8873 O O   . ALA D 2 286 ? -61.872 15.356  16.718  1   64.55  ? 282 ALA C O   1 
ATOM   8874 C CB  . ALA D 2 286 ? -60.869 12.557  16.938  1   61.81  ? 282 ALA C CB  1 
ATOM   8875 N N   . HIS D 2 287 ? -60.863 15.581  18.726  1   61.71  ? 283 HIS C N   1 
ATOM   8876 C CA  . HIS D 2 287 ? -61.728 16.674  19.14   1   63.82  ? 283 HIS C CA  1 
ATOM   8877 C C   . HIS D 2 287 ? -61.705 17.771  18.074  1   65.47  ? 283 HIS C C   1 
ATOM   8878 O O   . HIS D 2 287 ? -60.678 17.969  17.414  1   63.83  ? 283 HIS C O   1 
ATOM   8879 C CB  . HIS D 2 287 ? -61.356 17.178  20.541  1   61.25  ? 283 HIS C CB  1 
ATOM   8880 C CG  . HIS D 2 287 ? -62.324 18.153  21.131  1   62.17  ? 283 HIS C CG  1 
ATOM   8881 N ND1 . HIS D 2 287 ? -62.543 19.406  20.594  1   64.23  ? 283 HIS C ND1 1 
ATOM   8882 C CD2 . HIS D 2 287 ? -63.127 18.064  22.198  1   61.85  ? 283 HIS C CD2 1 
ATOM   8883 C CE1 . HIS D 2 287 ? -63.451 20.047  21.314  1   66.07  ? 283 HIS C CE1 1 
ATOM   8884 N NE2 . HIS D 2 287 ? -63.81  19.252  22.302  1   65.14  ? 283 HIS C NE2 1 
ATOM   8885 N N   . PRO D 2 288 ? -62.855 18.456  17.847  1   68.27  ? 284 PRO C N   1 
ATOM   8886 C CA  . PRO D 2 288 ? -62.919 19.648  16.989  1   70.39  ? 284 PRO C CA  1 
ATOM   8887 C C   . PRO D 2 288 ? -61.828 20.706  17.158  1   68.83  ? 284 PRO C C   1 
ATOM   8888 O O   . PRO D 2 288 ? -61.523 21.419  16.193  1   69.13  ? 284 PRO C O   1 
ATOM   8889 C CB  . PRO D 2 288 ? -64.316 20.23   17.292  1   71.87  ? 284 PRO C CB  1 
ATOM   8890 C CG  . PRO D 2 288 ? -65.152 19.043  17.716  1   72.76  ? 284 PRO C CG  1 
ATOM   8891 C CD  . PRO D 2 288 ? -64.183 18.072  18.363  1   69.46  ? 284 PRO C CD  1 
ATOM   8892 N N   . PHE D 2 289 ? -61.271 20.807  18.382  1   64.87  ? 285 PHE C N   1 
ATOM   8893 C CA  . PHE D 2 289 ? -60.238 21.778  18.707  1   62.15  ? 285 PHE C CA  1 
ATOM   8894 C C   . PHE D 2 289 ? -59.097 21.656  17.704  1   64.03  ? 285 PHE C C   1 
ATOM   8895 O O   . PHE D 2 289 ? -58.58  22.668  17.25   1   65.79  ? 285 PHE C O   1 
ATOM   8896 C CB  . PHE D 2 289 ? -59.788 21.658  20.163  1   59.03  ? 285 PHE C CB  1 
ATOM   8897 C CG  . PHE D 2 289 ? -58.913 22.78   20.709  1   57.55  ? 285 PHE C CG  1 
ATOM   8898 C CD1 . PHE D 2 289 ? -59.429 24.059  20.891  1   59.81  ? 285 PHE C CD1 1 
ATOM   8899 C CD2 . PHE D 2 289 ? -57.595 22.548  21.105  1   54.61  ? 285 PHE C CD2 1 
ATOM   8900 C CE1 . PHE D 2 289 ? -58.654 25.085  21.416  1   57.88  ? 285 PHE C CE1 1 
ATOM   8901 C CE2 . PHE D 2 289 ? -56.817 23.575  21.625  1   52.21  ? 285 PHE C CE2 1 
ATOM   8902 C CZ  . PHE D 2 289 ? -57.345 24.843  21.779  1   54.82  ? 285 PHE C CZ  1 
ATOM   8903 N N   . PHE D 2 290 ? -58.767 20.428  17.29   1   65.01  ? 286 PHE C N   1 
ATOM   8904 C CA  . PHE D 2 290 ? -57.565 20.233  16.495  1   66.21  ? 286 PHE C CA  1 
ATOM   8905 C C   . PHE D 2 290 ? -57.846 20.137  14.998  1   69.45  ? 286 PHE C C   1 
ATOM   8906 O O   . PHE D 2 290 ? -57.011 19.61   14.273  1   71.61  ? 286 PHE C O   1 
ATOM   8907 C CB  . PHE D 2 290 ? -56.835 18.955  16.912  1   63.68  ? 286 PHE C CB  1 
ATOM   8908 C CG  . PHE D 2 290 ? -56.427 18.918  18.371  1   57.4   ? 286 PHE C CG  1 
ATOM   8909 C CD1 . PHE D 2 290 ? -55.436 19.766  18.836  1   55.42  ? 286 PHE C CD1 1 
ATOM   8910 C CD2 . PHE D 2 290 ? -57.023 18.016  19.246  1   55.93  ? 286 PHE C CD2 1 
ATOM   8911 C CE1 . PHE D 2 290 ? -55.065 19.728  20.166  1   54.35  ? 286 PHE C CE1 1 
ATOM   8912 C CE2 . PHE D 2 290 ? -56.645 17.983  20.575  1   52.72  ? 286 PHE C CE2 1 
ATOM   8913 C CZ  . PHE D 2 290 ? -55.683 18.85   21.031  1   52.42  ? 286 PHE C CZ  1 
ATOM   8914 N N   . GLN D 2 291 ? -58.967 20.671  14.51   1   74.94  ? 287 GLN C N   1 
ATOM   8915 C CA  . GLN D 2 291 ? -59.244 20.552  13.083  1   86.98  ? 287 GLN C CA  1 
ATOM   8916 C C   . GLN D 2 291 ? -58.203 21.321  12.258  1   89.28  ? 287 GLN C C   1 
ATOM   8917 O O   . GLN D 2 291 ? -57.807 20.874  11.179  1   88.28  ? 287 GLN C O   1 
ATOM   8918 C CB  . GLN D 2 291 ? -60.687 20.918  12.728  1   96.56  ? 287 GLN C CB  1 
ATOM   8919 C CG  . GLN D 2 291 ? -61.063 22.353  13.089  1   110.12 ? 287 GLN C CG  1 
ATOM   8920 C CD  . GLN D 2 291 ? -62.283 22.874  12.357  1   124.54 ? 287 GLN C CD  1 
ATOM   8921 O OE1 . GLN D 2 291 ? -62.226 23.871  11.621  1   130.73 ? 287 GLN C OE1 1 
ATOM   8922 N NE2 . GLN D 2 291 ? -63.409 22.202  12.556  1   127.75 ? 287 GLN C NE2 1 
ATOM   8923 N N   . ASP D 2 292 ? -57.757 22.473  12.783  1   90.11  ? 288 ASP C N   1 
ATOM   8924 C CA  . ASP D 2 292 ? -57.008 23.455  12.008  1   88.21  ? 288 ASP C CA  1 
ATOM   8925 C C   . ASP D 2 292 ? -55.54  23.4    12.404  1   81.19  ? 288 ASP C C   1 
ATOM   8926 O O   . ASP D 2 292 ? -54.741 24.207  11.941  1   82.68  ? 288 ASP C O   1 
ATOM   8927 C CB  . ASP D 2 292 ? -57.578 24.868  12.144  1   89.5   ? 288 ASP C CB  1 
ATOM   8928 C CG  . ASP D 2 292 ? -57.623 25.495  13.537  1   83.66  ? 288 ASP C CG  1 
ATOM   8929 O OD1 . ASP D 2 292 ? -57.246 24.82   14.515  1   76.78  ? 288 ASP C OD1 1 
ATOM   8930 O OD2 . ASP D 2 292 ? -58.045 26.669  13.635  1   84.11  ? 288 ASP C OD2 1 
ATOM   8931 N N   . VAL D 2 293 ? -55.209 22.43   13.254  1   73.99  ? 289 VAL C N   1 
ATOM   8932 C CA  . VAL D 2 293 ? -53.974 22.466  14.012  1   71.6   ? 289 VAL C CA  1 
ATOM   8933 C C   . VAL D 2 293 ? -52.784 22.414  13.057  1   69.27  ? 289 VAL C C   1 
ATOM   8934 O O   . VAL D 2 293 ? -52.81  21.667  12.088  1   72.25  ? 289 VAL C O   1 
ATOM   8935 C CB  . VAL D 2 293 ? -53.957 21.322  15.046  1   73.22  ? 289 VAL C CB  1 
ATOM   8936 C CG1 . VAL D 2 293 ? -53.827 19.928  14.426  1   70.39  ? 289 VAL C CG1 1 
ATOM   8937 C CG2 . VAL D 2 293 ? -52.892 21.551  16.107  1   71.86  ? 289 VAL C CG2 1 
ATOM   8938 N N   . THR D 2 294 ? -51.764 23.238  13.333  1   67.78  ? 290 THR C N   1 
ATOM   8939 C CA  . THR D 2 294 ? -50.55  23.346  12.53   1   68.72  ? 290 THR C CA  1 
ATOM   8940 C C   . THR D 2 294 ? -49.339 23.167  13.446  1   67.16  ? 290 THR C C   1 
ATOM   8941 O O   . THR D 2 294 ? -49.508 22.77   14.594  1   71.89  ? 290 THR C O   1 
ATOM   8942 C CB  . THR D 2 294 ? -50.49  24.686  11.788  1   68.32  ? 290 THR C CB  1 
ATOM   8943 O OG1 . THR D 2 294 ? -50.354 25.699  12.781  1   64.15  ? 290 THR C OG1 1 
ATOM   8944 C CG2 . THR D 2 294 ? -51.664 24.922  10.851  1   68.71  ? 290 THR C CG2 1 
ATOM   8945 N N   . LYS D 2 295 ? -48.131 23.502  12.966  1   65.21  ? 291 LYS C N   1 
ATOM   8946 C CA  . LYS D 2 295 ? -46.939 23.261  13.765  1   61.84  ? 291 LYS C CA  1 
ATOM   8947 C C   . LYS D 2 295 ? -45.996 24.47   13.765  1   60.35  ? 291 LYS C C   1 
ATOM   8948 O O   . LYS D 2 295 ? -44.924 24.406  13.164  1   58.63  ? 291 LYS C O   1 
ATOM   8949 C CB  . LYS D 2 295 ? -46.27  21.974  13.265  1   62.03  ? 291 LYS C CB  1 
ATOM   8950 C CG  . LYS D 2 295 ? -45.668 21.086  14.346  1   59.9   ? 291 LYS C CG  1 
ATOM   8951 C CD  . LYS D 2 295 ? -44.218 20.724  14.037  1   61.11  ? 291 LYS C CD  1 
ATOM   8952 C CE  . LYS D 2 295 ? -43.668 19.585  14.848  1   61.86  ? 291 LYS C CE  1 
ATOM   8953 N NZ  . LYS D 2 295 ? -42.277 19.282  14.506  1   61.5   ? 291 LYS C NZ  1 
ATOM   8954 N N   . PRO D 2 296 ? -46.319 25.573  14.491  1   60.72  ? 292 PRO C N   1 
ATOM   8955 C CA  . PRO D 2 296 ? -45.446 26.748  14.558  1   63.12  ? 292 PRO C CA  1 
ATOM   8956 C C   . PRO D 2 296 ? -44.148 26.479  15.316  1   65.86  ? 292 PRO C C   1 
ATOM   8957 O O   . PRO D 2 296 ? -44.101 25.603  16.185  1   67.84  ? 292 PRO C O   1 
ATOM   8958 C CB  . PRO D 2 296 ? -46.264 27.863  15.255  1   62.13  ? 292 PRO C CB  1 
ATOM   8959 C CG  . PRO D 2 296 ? -47.534 27.19   15.773  1   60.69  ? 292 PRO C CG  1 
ATOM   8960 C CD  . PRO D 2 296 ? -47.522 25.735  15.323  1   60.99  ? 292 PRO C CD  1 
ATOM   8961 N N   . VAL D 2 297 ? -43.121 27.286  15.015  1   66.8   ? 293 VAL C N   1 
ATOM   8962 C CA  . VAL D 2 297 ? -41.889 27.271  15.79   1   66.07  ? 293 VAL C CA  1 
ATOM   8963 C C   . VAL D 2 297 ? -42.053 28.249  16.958  1   65.9   ? 293 VAL C C   1 
ATOM   8964 O O   . VAL D 2 297 ? -42.89  29.145  16.874  1   64.94  ? 293 VAL C O   1 
ATOM   8965 C CB  . VAL D 2 297 ? -40.633 27.55   14.936  1   63.32  ? 293 VAL C CB  1 
ATOM   8966 C CG1 . VAL D 2 297 ? -40.686 26.808  13.603  1   62.41  ? 293 VAL C CG1 1 
ATOM   8967 C CG2 . VAL D 2 297 ? -40.406 29.036  14.717  1   61.77  ? 293 VAL C CG2 1 
ATOM   8968 N N   . PRO D 2 298 ? -41.322 28.075  18.092  1   65.01  ? 294 PRO C N   1 
ATOM   8969 C CA  . PRO D 2 298 ? -41.46  28.953  19.26   1   64.76  ? 294 PRO C CA  1 
ATOM   8970 C C   . PRO D 2 298 ? -40.488 30.123  19.243  1   70.48  ? 294 PRO C C   1 
ATOM   8971 O O   . PRO D 2 298 ? -39.532 30.111  18.473  1   74.39  ? 294 PRO C O   1 
ATOM   8972 C CB  . PRO D 2 298 ? -41.124 27.981  20.383  1   60.11  ? 294 PRO C CB  1 
ATOM   8973 C CG  . PRO D 2 298 ? -39.996 27.156  19.786  1   64.26  ? 294 PRO C CG  1 
ATOM   8974 C CD  . PRO D 2 298 ? -40.347 26.993  18.316  1   64.53  ? 294 PRO C CD  1 
ATOM   8975 N N   . HIS D 2 299 ? -40.719 31.078  20.152  1   81.77  ? 295 HIS C N   1 
ATOM   8976 C CA  . HIS D 2 299 ? -40.044 32.368  20.23   1   94.86  ? 295 HIS C CA  1 
ATOM   8977 C C   . HIS D 2 299 ? -38.929 32.316  21.283  1   95.33  ? 295 HIS C C   1 
ATOM   8978 O O   . HIS D 2 299 ? -39.105 32.802  22.405  1   95.19  ? 295 HIS C O   1 
ATOM   8979 C CB  . HIS D 2 299 ? -41.084 33.474  20.49   1   107.7  ? 295 HIS C CB  1 
ATOM   8980 C CG  . HIS D 2 299 ? -42.04  33.203  21.635  1   130.8  ? 295 HIS C CG  1 
ATOM   8981 N ND1 . HIS D 2 299 ? -41.981 33.834  22.868  1   132.2  ? 295 HIS C ND1 1 
ATOM   8982 C CD2 . HIS D 2 299 ? -43.104 32.368  21.712  1   125.05 ? 295 HIS C CD2 1 
ATOM   8983 C CE1 . HIS D 2 299 ? -42.961 33.39   23.651  1   120.04 ? 295 HIS C CE1 1 
ATOM   8984 N NE2 . HIS D 2 299 ? -43.652 32.492  22.972  1   121.53 ? 295 HIS C NE2 1 
ATOM   8985 N N   . LEU D 2 300 ? -37.792 31.702  20.918  1   93.03  ? 296 LEU C N   1 
ATOM   8986 C CA  . LEU D 2 300 ? -36.645 31.557  21.811  1   89.75  ? 296 LEU C CA  1 
ATOM   8987 C C   . LEU D 2 300 ? -35.495 32.447  21.303  1   90.94  ? 296 LEU C C   1 
ATOM   8988 O O   . LEU D 2 300 ? -34.949 33.208  22.13   1   87.76  ? 296 LEU C O   1 
ATOM   8989 C CB  . LEU D 2 300 ? -36.19  30.099  21.912  1   82.78  ? 296 LEU C CB  1 
ATOM   8990 C CG  . LEU D 2 300 ? -37.284 29.037  22.059  1   78.12  ? 296 LEU C CG  1 
ATOM   8991 C CD1 . LEU D 2 300 ? -36.805 27.707  21.504  1   71.52  ? 296 LEU C CD1 1 
ATOM   8992 C CD2 . LEU D 2 300 ? -37.723 28.895  23.5    1   75.19  ? 296 LEU C CD2 1 
HETATM 8993 N N1  . PYZ E 3 .   ? -31.934 -25.135 47.769  1   86.63  ? 501 PYZ D N1  1 
HETATM 8994 N N2  . PYZ E 3 .   ? -33.261 -24.853 47.927  1   80.97  ? 501 PYZ D N2  1 
HETATM 8995 C C3  . PYZ E 3 .   ? -33.762 -24.303 46.826  1   67.53  ? 501 PYZ D C3  1 
HETATM 8996 C C4  . PYZ E 3 .   ? -32.719 -24.228 45.956  1   67.82  ? 501 PYZ D C4  1 
HETATM 8997 I I4  . PYZ E 3 .   ? -32.862 -23.447 44.065  1   73.14  ? 501 PYZ D I4  1 
HETATM 8998 C C5  . PYZ E 3 .   ? -31.588 -24.753 46.558  1   69.89  ? 501 PYZ D C5  1 
HETATM 8999 N N1  . PYZ F 3 .   ? -21.793 -42.655 5.856   1   59.06  ? 601 PYZ A N1  1 
HETATM 9000 N N2  . PYZ F 3 .   ? -21.306 -41.408 5.721   1   56.09  ? 601 PYZ A N2  1 
HETATM 9001 C C3  . PYZ F 3 .   ? -21.689 -40.635 6.76    1   55.86  ? 601 PYZ A C3  1 
HETATM 9002 C C4  . PYZ F 3 .   ? -22.46  -41.411 7.628   1   56.52  ? 601 PYZ A C4  1 
HETATM 9003 I I4  . PYZ F 3 .   ? -23.354 -40.817 9.408   1   68.02  ? 601 PYZ A I4  1 
HETATM 9004 C C5  . PYZ F 3 .   ? -22.507 -42.659 7.001   1   60.59  ? 601 PYZ A C5  1 
HETATM 9005 N N1  A PYZ G 3 .   ? -9.416  -22.679 24.594  0.5 35.53  ? 602 PYZ A N1  1 
HETATM 9006 N N1  B PYZ G 3 .   ? -9.534  -22.487 24.408  0.5 34.67  ? 602 PYZ A N1  1 
HETATM 9007 N N2  A PYZ G 3 .   ? -8.083  -22.532 24.498  0.5 36.54  ? 602 PYZ A N2  1 
HETATM 9008 N N2  B PYZ G 3 .   ? -9.993  -21.471 23.652  0.5 34.45  ? 602 PYZ A N2  1 
HETATM 9009 C C3  A PYZ G 3 .   ? -7.768  -21.602 23.575  0.5 36.59  ? 602 PYZ A C3  1 
HETATM 9010 C C3  B PYZ G 3 .   ? -8.994  -20.864 22.992  0.5 35.04  ? 602 PYZ A C3  1 
HETATM 9011 C C4  A PYZ G 3 .   ? -8.954  -21.114 23.063  0.5 35.54  ? 602 PYZ A C4  1 
HETATM 9012 C C4  B PYZ G 3 .   ? -7.847  -21.528 23.334  0.5 35.39  ? 602 PYZ A C4  1 
HETATM 9013 I I4  A PYZ G 3 .   ? -9.184  -19.653 21.615  0.5 34.48  ? 602 PYZ A I4  1 
HETATM 9014 I I4  B PYZ G 3 .   ? -5.947  -21.109 22.654  0.5 35.72  ? 602 PYZ A I4  1 
HETATM 9015 C C5  A PYZ G 3 .   ? -9.955  -21.823 23.73   0.5 34.7   ? 602 PYZ A C5  1 
HETATM 9016 C C5  B PYZ G 3 .   ? -8.225  -22.527 24.229  0.5 35.66  ? 602 PYZ A C5  1 
HETATM 9017 N N1  A PYZ H 3 .   ? -8.606  -9.043  33.376  0.5 53.01  ? 604 PYZ A N1  1 
HETATM 9018 N N1  B PYZ H 3 .   ? -3.482  -12.301 28.436  0.5 70.35  ? 604 PYZ A N1  1 
HETATM 9019 N N2  A PYZ H 3 .   ? -8.992  -10.153 34.012  0.5 51.51  ? 604 PYZ A N2  1 
HETATM 9020 N N2  B PYZ H 3 .   ? -4.54   -12.587 27.655  0.5 66.07  ? 604 PYZ A N2  1 
HETATM 9021 C C3  A PYZ H 3 .   ? -8.436  -11.23  33.467  0.5 51.65  ? 604 PYZ A C3  1 
HETATM 9022 C C3  B PYZ H 3 .   ? -5.686  -12.446 28.324  0.5 66.17  ? 604 PYZ A C3  1 
HETATM 9023 C C4  A PYZ H 3 .   ? -7.647  -10.792 32.437  0.5 55.18  ? 604 PYZ A C4  1 
HETATM 9024 C C4  B PYZ H 3 .   ? -5.349  -12.078 29.588  0.5 73.99  ? 604 PYZ A C4  1 
HETATM 9025 I I4  A PYZ H 3 .   ? -6.533  -11.959 31.141  0.5 72.11  ? 604 PYZ A I4  1 
HETATM 9026 I I4  B PYZ H 3 .   ? -6.66   -11.698 31.134  0.5 99.14  ? 604 PYZ A I4  1 
HETATM 9027 C C5  A PYZ H 3 .   ? -7.788  -9.408  32.417  0.5 53.53  ? 604 PYZ A C5  1 
HETATM 9028 C C5  B PYZ H 3 .   ? -3.963  -11.996 29.62   0.5 73.27  ? 604 PYZ A C5  1 
HETATM 9029 N N1  . PYZ I 3 .   ? -5.287  -45.501 15.106  1   76.88  ? 606 PYZ A N1  1 
HETATM 9030 N N2  . PYZ I 3 .   ? -4.049  -45.364 14.585  1   78.88  ? 606 PYZ A N2  1 
HETATM 9031 C C3  . PYZ I 3 .   ? -4.012  -45.825 13.334  1   77.96  ? 606 PYZ A C3  1 
HETATM 9032 C C4  . PYZ I 3 .   ? -5.278  -46.276 13.048  1   75.17  ? 606 PYZ A C4  1 
HETATM 9033 I I4  . PYZ I 3 .   ? -5.881  -47.144 11.276  1   89.55  ? 606 PYZ A I4  1 
HETATM 9034 C C5  . PYZ I 3 .   ? -6.048  -46.048 14.178  1   70.58  ? 606 PYZ A C5  1 
HETATM 9035 N N1  . PYZ J 3 .   ? -16.316 19.25   1.802   1   94.2   ? 501 PYZ B N1  1 
HETATM 9036 N N2  . PYZ J 3 .   ? -15.513 19.034  2.864   1   93.91  ? 501 PYZ B N2  1 
HETATM 9037 C C3  . PYZ J 3 .   ? -15.114 17.753  2.908   1   99.12  ? 501 PYZ B C3  1 
HETATM 9038 C C4  . PYZ J 3 .   ? -15.677 17.11   1.809   1   102.5  ? 501 PYZ B C4  1 
HETATM 9039 I I4  . PYZ J 3 .   ? -15.47  15.101  1.322   1   91.33  ? 501 PYZ B I4  1 
HETATM 9040 C C5  . PYZ J 3 .   ? -16.445 18.087  1.164   1   95.96  ? 501 PYZ B C5  1 
HETATM 9041 N N1  . PYZ K 3 .   ? -20.072 19.163  4.092   1   72.94  ? 502 PYZ B N1  1 
HETATM 9042 N N2  . PYZ K 3 .   ? -20.645 18.856  2.899   1   76.41  ? 502 PYZ B N2  1 
HETATM 9043 C C3  . PYZ K 3 .   ? -20.249 17.664  2.438   1   70.97  ? 502 PYZ B C3  1 
HETATM 9044 C C4  . PYZ K 3 .   ? -19.403 17.175  3.389   1   77.73  ? 502 PYZ B C4  1 
HETATM 9045 I I4  . PYZ K 3 .   ? -18.476 15.326  3.276   1   103.57 ? 502 PYZ B I4  1 
HETATM 9046 C C5  . PYZ K 3 .   ? -19.327 18.129  4.41    1   72.45  ? 502 PYZ B C5  1 
HETATM 9047 N N1  . PYZ L 3 .   ? -17.02  -3.493  21.398  1   93.31  ? 503 PYZ B N1  1 
HETATM 9048 N N2  . PYZ L 3 .   ? -17.357 -3.47   20.091  1   84.37  ? 503 PYZ B N2  1 
HETATM 9049 C C3  . PYZ L 3 .   ? -16.399 -2.858  19.381  1   93.08  ? 503 PYZ B C3  1 
HETATM 9050 C C4  . PYZ L 3 .   ? -15.37  -2.464  20.274  1   108.12 ? 503 PYZ B C4  1 
HETATM 9051 I I4  . PYZ L 3 .   ? -13.586 -1.458  19.876  1   143.5  ? 503 PYZ B I4  1 
HETATM 9052 C C5  . PYZ L 3 .   ? -15.838 -2.892  21.524  1   96.7   ? 503 PYZ B C5  1 
HETATM 9053 N N1  A PYZ M 3 .   ? -26.008 -9.663  12.313  0.5 30     ? 504 PYZ B N1  1 
HETATM 9054 N N1  B PYZ M 3 .   ? -20.281 -9.845  10.822  0.5 65.38  ? 504 PYZ B N1  1 
HETATM 9055 N N2  A PYZ M 3 .   ? -26.489 -8.469  11.903  0.5 30     ? 504 PYZ B N2  1 
HETATM 9056 N N2  B PYZ M 3 .   ? -21.251 -10.248 11.674  0.5 71.04  ? 504 PYZ B N2  1 
HETATM 9057 C C3  A PYZ M 3 .   ? -25.848 -8.033  10.814  0.5 30     ? 504 PYZ B C3  1 
HETATM 9058 C C3  B PYZ M 3 .   ? -22.468 -9.996  11.167  0.5 75.05  ? 504 PYZ B C3  1 
HETATM 9059 C C4  A PYZ M 3 .   ? -24.913 -8.985  10.508  0.5 30     ? 504 PYZ B C4  1 
HETATM 9060 C C4  B PYZ M 3 .   ? -22.264 -9.368  9.968   0.5 78.56  ? 504 PYZ B C4  1 
HETATM 9061 I I4  A PYZ M 3 .   ? -23.599 -8.92   8.916   0.5 30     ? 504 PYZ B I4  1 
HETATM 9062 I I4  B PYZ M 3 .   ? -23.807 -8.752  8.744   0.5 100.45 ? 504 PYZ B I4  1 
HETATM 9063 C C5  A PYZ M 3 .   ? -25.042 -9.983  11.469  0.5 30     ? 504 PYZ B C5  1 
HETATM 9064 C C5  B PYZ M 3 .   ? -20.888 -9.3    9.775   0.5 67.43  ? 504 PYZ B C5  1 
HETATM 9065 N N1  A PYZ N 3 .   ? -32.681 17.839  28.438  0.5 25.34  ? 501 PYZ C N1  1 
HETATM 9066 N N1  B PYZ N 3 .   ? -33.694 18.212  31.776  0.5 41.38  ? 501 PYZ C N1  1 
HETATM 9067 N N2  A PYZ N 3 .   ? -32.576 17.237  27.256  0.5 25.2   ? 501 PYZ C N2  1 
HETATM 9068 N N2  B PYZ N 3 .   ? -33.59  17.387  32.824  0.5 40.07  ? 501 PYZ C N2  1 
HETATM 9069 C C3  A PYZ N 3 .   ? -32.885 15.952  27.347  0.5 25.55  ? 501 PYZ C C3  1 
HETATM 9070 C C3  B PYZ N 3 .   ? -33.386 16.132  32.414  0.5 40.88  ? 501 PYZ C C3  1 
HETATM 9071 C C4  A PYZ N 3 .   ? -33.204 15.714  28.657  0.5 26.77  ? 501 PYZ C C4  1 
HETATM 9072 C C4  B PYZ N 3 .   ? -33.306 16.144  31.038  0.5 41.86  ? 501 PYZ C C4  1 
HETATM 9073 I I4  A PYZ N 3 .   ? -33.756 13.909  29.507  0.5 33.44  ? 501 PYZ C I4  1 
HETATM 9074 I I4  B PYZ N 3 .   ? -32.968 14.52   29.799  0.5 47.26  ? 501 PYZ C I4  1 
HETATM 9075 C C5  A PYZ N 3 .   ? -33.056 16.933  29.301  0.5 25.52  ? 501 PYZ C C5  1 
HETATM 9076 C C5  B PYZ N 3 .   ? -33.504 17.47   30.681  0.5 41.87  ? 501 PYZ C C5  1 
HETATM 9077 N N1  . PYZ O 3 .   ? -69.074 21.042  47.963  1   73.07  ? 502 PYZ C N1  1 
HETATM 9078 N N2  . PYZ O 3 .   ? -68.173 21.586  47.112  1   69.71  ? 502 PYZ C N2  1 
HETATM 9079 C C3  . PYZ O 3 .   ? -68.326 21.118  45.867  1   69.35  ? 502 PYZ C C3  1 
HETATM 9080 C C4  . PYZ O 3 .   ? -69.383 20.224  45.906  1   76.33  ? 502 PYZ C C4  1 
HETATM 9081 I I4  . PYZ O 3 .   ? -70.151 19.137  44.312  1   76.3   ? 502 PYZ C I4  1 
HETATM 9082 C C5  . PYZ O 3 .   ? -69.823 20.214  47.238  1   76.02  ? 502 PYZ C C5  1 
HETATM 9083 N N1  . PYZ P 3 .   ? -17.905 11.916  31.645  1   63.81  ? 504 PYZ C N1  1 
HETATM 9084 N N2  . PYZ P 3 .   ? -18.203 12.543  30.486  1   60.47  ? 504 PYZ C N2  1 
HETATM 9085 C C3  . PYZ P 3 .   ? -19.343 13.235  30.62   1   61.39  ? 504 PYZ C C3  1 
HETATM 9086 C C4  . PYZ P 3 .   ? -19.803 13.043  31.919  1   61.76  ? 504 PYZ C C4  1 
HETATM 9087 I I4  . PYZ P 3 .   ? -21.538 13.815  32.74   1   67.55  ? 504 PYZ C I4  1 
HETATM 9088 C C5  . PYZ P 3 .   ? -18.874 12.204  32.522  1   60.53  ? 504 PYZ C C5  1 
HETATM 9089 N N1  . EPE Q 4 .   ? -29.4   -0.361  25.337  1   87.21  ? 505 EPE C N1  1 
HETATM 9090 C C2  . EPE Q 4 .   ? -28.476 -1.318  24.691  1   96.1   ? 505 EPE C C2  1 
HETATM 9091 C C3  . EPE Q 4 .   ? -28.068 -2.414  25.645  1   99.16  ? 505 EPE C C3  1 
HETATM 9092 N N4  . EPE Q 4 .   ? -27.772 -1.896  27.006  1   99.22  ? 505 EPE C N4  1 
HETATM 9093 C C5  . EPE Q 4 .   ? -28.949 -1.215  27.582  1   84.12  ? 505 EPE C C5  1 
HETATM 9094 C C6  . EPE Q 4 .   ? -30.004 -0.951  26.538  1   78.63  ? 505 EPE C C6  1 
HETATM 9095 C C7  . EPE Q 4 .   ? -27.33  -2.998  27.872  1   99.12  ? 505 EPE C C7  1 
HETATM 9096 C C8  . EPE Q 4 .   ? -25.893 -3.46   27.67   1   99.5   ? 505 EPE C C8  1 
HETATM 9097 O O8  . EPE Q 4 .   ? -25.635 -3.948  26.368  1   101.33 ? 505 EPE C O8  1 
HETATM 9098 C C9  . EPE Q 4 .   ? -28.742 0.903   25.652  1   83.49  ? 505 EPE C C9  1 
HETATM 9099 C C10 . EPE Q 4 .   ? -29.209 2.061   24.789  1   79.98  ? 505 EPE C C10 1 
HETATM 9100 S S   . EPE Q 4 .   ? -30.962 2.105   24.55   1   70.23  ? 505 EPE C S   1 
HETATM 9101 O O1S . EPE Q 4 .   ? -31.178 1.418   23.308  1   72.14  ? 505 EPE C O1S 1 
HETATM 9102 O O2S . EPE Q 4 .   ? -31.305 3.622   24.394  1   70.47  ? 505 EPE C O2S 1 
HETATM 9103 O O3S . EPE Q 4 .   ? -31.555 1.645   25.773  1   71.3   ? 505 EPE C O3S 1 
HETATM 9104 O O   . HOH R 5 .   ? -24.896 -25.381 31.963  1   28.63  ? 601 HOH D O   1 
HETATM 9105 O O   . HOH R 5 .   ? -27.842 -30.038 29.948  1   24.25  ? 602 HOH D O   1 
HETATM 9106 O O   . HOH R 5 .   ? -40.375 -1.889  42.621  1   42.82  ? 603 HOH D O   1 
HETATM 9107 O O   . HOH R 5 .   ? -47.21  -8.225  45.895  1   33.87  ? 604 HOH D O   1 
HETATM 9108 O O   . HOH R 5 .   ? -19.209 -12.343 47.244  1   37.55  ? 605 HOH D O   1 
HETATM 9109 O O   . HOH R 5 .   ? -38.032 -27.08  34.052  1   32.2   ? 606 HOH D O   1 
HETATM 9110 O O   . HOH R 5 .   ? -49.859 -17.248 18.527  1   43.62  ? 607 HOH D O   1 
HETATM 9111 O O   . HOH R 5 .   ? -37.195 -26.174 44.855  1   37.27  ? 608 HOH D O   1 
HETATM 9112 O O   . HOH R 5 .   ? -39.751 -18.653 29.865  1   43.89  ? 609 HOH D O   1 
HETATM 9113 O O   . HOH R 5 .   ? -41.945 -29.228 45.385  1   42.52  ? 610 HOH D O   1 
HETATM 9114 O O   . HOH R 5 .   ? -50.646 -12.381 42.625  1   32.1   ? 611 HOH D O   1 
HETATM 9115 O O   . HOH R 5 .   ? -58.544 -7.366  21.692  1   51.14  ? 612 HOH D O   1 
HETATM 9116 O O   . HOH R 5 .   ? -46.018 -17.546 44.991  1   40.14  ? 613 HOH D O   1 
HETATM 9117 O O   . HOH R 5 .   ? -27.774 -23.291 42.229  1   23.3   ? 614 HOH D O   1 
HETATM 9118 O O   . HOH R 5 .   ? -32.438 -32.54  38.873  1   43.5   ? 615 HOH D O   1 
HETATM 9119 O O   . HOH R 5 .   ? -52.735 -7.992  33.698  1   41.53  ? 616 HOH D O   1 
HETATM 9120 O O   . HOH R 5 .   ? -45.703 -4.949  46.667  1   30.51  ? 617 HOH D O   1 
HETATM 9121 O O   . HOH R 5 .   ? -20.234 -23.751 27.919  1   39.73  ? 618 HOH D O   1 
HETATM 9122 O O   . HOH R 5 .   ? -26.76  -4.465  40.786  1   35.55  ? 619 HOH D O   1 
HETATM 9123 O O   . HOH R 5 .   ? -42.527 -12.994 27.025  1   34.2   ? 620 HOH D O   1 
HETATM 9124 O O   . HOH R 5 .   ? -43.701 -20.208 27.315  1   40.11  ? 621 HOH D O   1 
HETATM 9125 O O   . HOH R 5 .   ? -47.57  -32.613 35.964  1   44.23  ? 622 HOH D O   1 
HETATM 9126 O O   . HOH R 5 .   ? -34.393 -33.191 33.439  1   35.62  ? 623 HOH D O   1 
HETATM 9127 O O   . HOH R 5 .   ? -27.918 -23.563 44.798  1   33.49  ? 624 HOH D O   1 
HETATM 9128 O O   . HOH R 5 .   ? -42.266 -15.4   25.243  1   38.2   ? 625 HOH D O   1 
HETATM 9129 O O   . HOH R 5 .   ? -26.865 -21.142 26.717  1   44.71  ? 626 HOH D O   1 
HETATM 9130 O O   . HOH R 5 .   ? -25.101 -22.911 27.209  1   29.34  ? 627 HOH D O   1 
HETATM 9131 O O   . HOH R 5 .   ? -35.622 -3.77   46.402  1   8.78   ? 628 HOH D O   1 
HETATM 9132 O O   . HOH R 5 .   ? -22.17  -15.725 26.432  1   44.58  ? 629 HOH D O   1 
HETATM 9133 O O   . HOH R 5 .   ? -33.364 -32.127 30.635  1   31.35  ? 630 HOH D O   1 
HETATM 9134 O O   . HOH R 5 .   ? -39.144 -30.198 31.766  1   31.73  ? 631 HOH D O   1 
HETATM 9135 O O   . HOH R 5 .   ? -44.581 -28.358 39.676  1   36.6   ? 632 HOH D O   1 
HETATM 9136 O O   . HOH R 5 .   ? -20.847 -25.306 40.089  1   26.36  ? 633 HOH D O   1 
HETATM 9137 O O   . HOH R 5 .   ? -43.233 -1.474  35.416  1   27.29  ? 634 HOH D O   1 
HETATM 9138 O O   . HOH R 5 .   ? -32.928 -0.962  52.613  1   21.47  ? 635 HOH D O   1 
HETATM 9139 O O   . HOH R 5 .   ? -38.768 -3.722  27.884  1   29.78  ? 636 HOH D O   1 
HETATM 9140 O O   . HOH R 5 .   ? -38.275 -27.027 25.252  1   48.12  ? 637 HOH D O   1 
HETATM 9141 O O   . HOH R 5 .   ? -48.106 -11.215 16.871  1   36.33  ? 638 HOH D O   1 
HETATM 9142 O O   . HOH R 5 .   ? -32.967 -10.521 25.52   1   32.87  ? 639 HOH D O   1 
HETATM 9143 O O   . HOH R 5 .   ? -30.706 -4.231  51.42   1   41.29  ? 640 HOH D O   1 
HETATM 9144 O O   . HOH R 5 .   ? -44.275 -6.789  32.66   1   42.64  ? 641 HOH D O   1 
HETATM 9145 O O   . HOH R 5 .   ? -59.317 4.374   27.724  1   46.15  ? 642 HOH D O   1 
HETATM 9146 O O   . HOH R 5 .   ? -21.947 -20.289 25.495  1   33.8   ? 643 HOH D O   1 
HETATM 9147 O O   . HOH R 5 .   ? -43.622 -21.443 30.141  1   27.51  ? 644 HOH D O   1 
HETATM 9148 O O   . HOH R 5 .   ? -39.039 -32.485 36.62   1   33.25  ? 645 HOH D O   1 
HETATM 9149 O O   . HOH R 5 .   ? -42.19  -17.936 30.49   1   40.15  ? 646 HOH D O   1 
HETATM 9150 O O   . HOH R 5 .   ? -44.245 -18.797 29.699  1   28.68  ? 647 HOH D O   1 
HETATM 9151 O O   . HOH S 5 .   ? 13.612  -32.337 -1.958  1   20.65  ? 701 HOH A O   1 
HETATM 9152 O O   . HOH S 5 .   ? -1.34   -25.711 -18.993 1   40.41  ? 702 HOH A O   1 
HETATM 9153 O O   . HOH S 5 .   ? -12.718 -28.954 -5.238  1   26.62  ? 703 HOH A O   1 
HETATM 9154 O O   . HOH S 5 .   ? -21.477 -17.597 31.745  1   31.86  ? 704 HOH A O   1 
HETATM 9155 O O   . HOH S 5 .   ? -4.646  -19.095 -10.774 1   33.86  ? 705 HOH A O   1 
HETATM 9156 O O   . HOH S 5 .   ? -21.508 -18.672 27.622  1   35.12  ? 706 HOH A O   1 
HETATM 9157 O O   . HOH S 5 .   ? -12.677 -16.911 -9.279  1   35.03  ? 707 HOH A O   1 
HETATM 9158 O O   . HOH S 5 .   ? -3.043  -19.999 -5.552  1   20.89  ? 708 HOH A O   1 
HETATM 9159 O O   . HOH S 5 .   ? -23.983 -44.415 10.574  1   41.26  ? 709 HOH A O   1 
HETATM 9160 O O   . HOH S 5 .   ? -4.981  -37.964 -4.467  1   34.76  ? 710 HOH A O   1 
HETATM 9161 O O   . HOH S 5 .   ? -2.992  -42.569 15.011  1   42.46  ? 711 HOH A O   1 
HETATM 9162 O O   . HOH S 5 .   ? 1.954   -53.414 -0.869  1   50.14  ? 712 HOH A O   1 
HETATM 9163 O O   . HOH S 5 .   ? -8.158  -16.689 -4.229  1   34.85  ? 713 HOH A O   1 
HETATM 9164 O O   . HOH S 5 .   ? -19.596 -30.472 19.535  1   28.35  ? 714 HOH A O   1 
HETATM 9165 O O   . HOH S 5 .   ? 8.837   -31.362 -15.025 1   27.09  ? 715 HOH A O   1 
HETATM 9166 O O   . HOH S 5 .   ? 1.299   -38.615 8.121   1   37.09  ? 716 HOH A O   1 
HETATM 9167 O O   . HOH S 5 .   ? -7.966  -23.558 -4.464  1   35.55  ? 717 HOH A O   1 
HETATM 9168 O O   . HOH S 5 .   ? -15.063 -12.223 -5.453  1   48.71  ? 718 HOH A O   1 
HETATM 9169 O O   . HOH S 5 .   ? -12.988 -10.328 2.455   1   30.12  ? 719 HOH A O   1 
HETATM 9170 O O   . HOH S 5 .   ? -8.667  -10.721 -8.331  1   31.66  ? 720 HOH A O   1 
HETATM 9171 O O   . HOH S 5 .   ? -18.939 -24.561 19.31   1   17.95  ? 721 HOH A O   1 
HETATM 9172 O O   . HOH S 5 .   ? -9.904  -28.866 -13.912 1   28.86  ? 722 HOH A O   1 
HETATM 9173 O O   . HOH S 5 .   ? -12.737 -12.868 -9.579  1   35.67  ? 723 HOH A O   1 
HETATM 9174 O O   . HOH S 5 .   ? -21.998 -28.801 8.07    1   34     ? 724 HOH A O   1 
HETATM 9175 O O   . HOH S 5 .   ? -3.669  -25.447 2.162   1   22.56  ? 725 HOH A O   1 
HETATM 9176 O O   . HOH S 5 .   ? -16.106 -42.844 -2.173  1   40.41  ? 726 HOH A O   1 
HETATM 9177 O O   . HOH S 5 .   ? -15.502 -27.683 0.874   1   32.59  ? 727 HOH A O   1 
HETATM 9178 O O   . HOH S 5 .   ? -19.256 -21.233 16.795  1   35.82  ? 728 HOH A O   1 
HETATM 9179 O O   . HOH S 5 .   ? -12.344 -11.175 5.215   1   46.21  ? 729 HOH A O   1 
HETATM 9180 O O   . HOH S 5 .   ? -19.733 -13.469 -0.983  1   33.96  ? 730 HOH A O   1 
HETATM 9181 O O   . HOH S 5 .   ? -6.157  -52.311 3.867   1   55.34  ? 731 HOH A O   1 
HETATM 9182 O O   . HOH S 5 .   ? 3.702   -20.853 -1.087  1   20.37  ? 732 HOH A O   1 
HETATM 9183 O O   . HOH S 5 .   ? 1.808   -32.152 6.198   1   19.57  ? 733 HOH A O   1 
HETATM 9184 O O   . HOH S 5 .   ? -0.023  -33.278 8.1     1   28.63  ? 734 HOH A O   1 
HETATM 9185 O O   . HOH S 5 .   ? 6.113   -19.7   -15.147 1   37.74  ? 735 HOH A O   1 
HETATM 9186 O O   . HOH S 5 .   ? -20.437 -13.518 -3.856  1   32.57  ? 736 HOH A O   1 
HETATM 9187 O O   . HOH S 5 .   ? -6.654  -25.787 -11.434 1   29.37  ? 737 HOH A O   1 
HETATM 9188 O O   . HOH S 5 .   ? -12.212 -28.84  -2.668  1   30.62  ? 738 HOH A O   1 
HETATM 9189 O O   . HOH S 5 .   ? -3.402  -36.511 -5.98   1   23.92  ? 739 HOH A O   1 
HETATM 9190 O O   . HOH S 5 .   ? -3.757  -5.259  7.34    1   35.29  ? 740 HOH A O   1 
HETATM 9191 O O   . HOH S 5 .   ? 4.781   -22.034 7.641   1   32.49  ? 741 HOH A O   1 
HETATM 9192 O O   . HOH S 5 .   ? -5.536  -15.88  -4.668  1   40.82  ? 742 HOH A O   1 
HETATM 9193 O O   . HOH S 5 .   ? -6.288  -24.258 5.641   1   29.16  ? 743 HOH A O   1 
HETATM 9194 O O   . HOH S 5 .   ? -3.612  -9.867  32.582  1   34.32  ? 744 HOH A O   1 
HETATM 9195 O O   . HOH S 5 .   ? -5.259  -40.881 30.424  1   38.16  ? 745 HOH A O   1 
HETATM 9196 O O   . HOH S 5 .   ? -19.42  -10.079 32.311  1   43.01  ? 746 HOH A O   1 
HETATM 9197 O O   . HOH S 5 .   ? -15.003 -12.286 -8.925  1   38.55  ? 747 HOH A O   1 
HETATM 9198 O O   . HOH S 5 .   ? -18.42  -18.449 16.983  1   32.59  ? 748 HOH A O   1 
HETATM 9199 O O   . HOH S 5 .   ? -17.561 -23.674 31.017  1   35.63  ? 749 HOH A O   1 
HETATM 9200 O O   . HOH S 5 .   ? 3.758   -41.2   3.579   1   35.99  ? 750 HOH A O   1 
HETATM 9201 O O   . HOH S 5 .   ? 7.233   -29.781 -18.005 1   33.13  ? 751 HOH A O   1 
HETATM 9202 O O   . HOH S 5 .   ? -12.832 -49.835 4.289   1   52.04  ? 752 HOH A O   1 
HETATM 9203 O O   . HOH S 5 .   ? 0.196   -21.689 21.666  1   48.3   ? 753 HOH A O   1 
HETATM 9204 O O   . HOH S 5 .   ? 5.764   -45.471 -7.839  1   31.11  ? 754 HOH A O   1 
HETATM 9205 O O   . HOH S 5 .   ? -18.544 -38.969 -0.964  1   33.68  ? 755 HOH A O   1 
HETATM 9206 O O   . HOH S 5 .   ? 12.031  -22.586 -1.608  1   30.45  ? 756 HOH A O   1 
HETATM 9207 O O   . HOH S 5 .   ? 0.458   -37.803 -10.222 1   15.15  ? 757 HOH A O   1 
HETATM 9208 O O   . HOH S 5 .   ? -23.925 -31.38  14.566  1   31.87  ? 758 HOH A O   1 
HETATM 9209 O O   . HOH S 5 .   ? 7.486   -23.034 -5.033  1   16.83  ? 759 HOH A O   1 
HETATM 9210 O O   . HOH S 5 .   ? -14.406 -27.354 -1.915  1   26.27  ? 760 HOH A O   1 
HETATM 9211 O O   . HOH S 5 .   ? -0.646  -15.298 -6.234  1   30.77  ? 761 HOH A O   1 
HETATM 9212 O O   . HOH S 5 .   ? -10.71  -11.284 -10.231 1   40.85  ? 762 HOH A O   1 
HETATM 9213 O O   . HOH S 5 .   ? -18.381 -15.796 30.344  1   35.34  ? 763 HOH A O   1 
HETATM 9214 O O   . HOH S 5 .   ? -16.925 -38.727 -3.11   1   32.29  ? 764 HOH A O   1 
HETATM 9215 O O   . HOH S 5 .   ? -2.403  -8.341  8.817   1   40.34  ? 765 HOH A O   1 
HETATM 9216 O O   . HOH S 5 .   ? -14.659 -3.858  31.51   1   33.46  ? 766 HOH A O   1 
HETATM 9217 O O   . HOH S 5 .   ? 2.892   -24.544 13.177  1   35.95  ? 767 HOH A O   1 
HETATM 9218 O O   . HOH S 5 .   ? 6.46    -19.425 2.845   1   33.26  ? 768 HOH A O   1 
HETATM 9219 O O   . HOH S 5 .   ? -23.921 -29.327 10.504  1   27.94  ? 769 HOH A O   1 
HETATM 9220 O O   . HOH S 5 .   ? -18.992 -37.217 15.944  1   28.97  ? 770 HOH A O   1 
HETATM 9221 O O   . HOH S 5 .   ? -22.750 -43.612 1.510   1   31.05  ? 771 HOH A O   1 
HETATM 9222 O O   . HOH S 5 .   ? 0.432   -18.742 7.193   1   29.26  ? 772 HOH A O   1 
HETATM 9223 O O   . HOH S 5 .   ? -16.616 -10.909 -0.021  1   35.52  ? 773 HOH A O   1 
HETATM 9224 O O   . HOH S 5 .   ? -19.137 -31.51  23.493  1   31.99  ? 774 HOH A O   1 
HETATM 9225 O O   . HOH S 5 .   ? 8.815   -22.617 -7.382  1   28.63  ? 775 HOH A O   1 
HETATM 9226 O O   . HOH S 5 .   ? 12.059  -39.670 -10.564 1   31.56  ? 776 HOH A O   1 
HETATM 9227 O O   . HOH S 5 .   ? -4.524  -36.083 -8.554  1   26.45  ? 777 HOH A O   1 
HETATM 9228 O O   . HOH S 5 .   ? 12.652  -31.906 -17.765 1   43.36  ? 778 HOH A O   1 
HETATM 9229 O O   . HOH S 5 .   ? -2.597  -19.438 -12.269 1   19.81  ? 779 HOH A O   1 
HETATM 9230 O O   . HOH S 5 .   ? -13.144 -18.445 40.269  1   29.21  ? 780 HOH A O   1 
HETATM 9231 O O   . HOH S 5 .   ? -13.629 -26.82  31.752  1   30.26  ? 781 HOH A O   1 
HETATM 9232 O O   . HOH S 5 .   ? -0.763  -53.506 -0.074  1   45.17  ? 782 HOH A O   1 
HETATM 9233 O O   . HOH S 5 .   ? -20.909 -35.937 16.586  1   28.12  ? 783 HOH A O   1 
HETATM 9234 O O   . HOH S 5 .   ? 7.605   -23.805 8.145   1   46.75  ? 784 HOH A O   1 
HETATM 9235 O O   . HOH S 5 .   ? 4.127   -26.338 11.669  1   24.17  ? 785 HOH A O   1 
HETATM 9236 O O   . HOH T 5 .   ? -6.037  -6.669  5.13    1   50.41  ? 601 HOH B O   1 
HETATM 9237 O O   . HOH T 5 .   ? -45.991 -16.432 -13.795 1   28.5   ? 602 HOH B O   1 
HETATM 9238 O O   . HOH T 5 .   ? -32.625 -10.691 0.417   1   36.69  ? 603 HOH B O   1 
HETATM 9239 O O   . HOH T 5 .   ? -13.212 3.898   -6.127  1   40.52  ? 604 HOH B O   1 
HETATM 9240 O O   . HOH T 5 .   ? -36.944 -13.74  -4.423  1   35.51  ? 605 HOH B O   1 
HETATM 9241 O O   . HOH T 5 .   ? -41.022 -17.189 -15.79  1   20.87  ? 606 HOH B O   1 
HETATM 9242 O O   . HOH T 5 .   ? -29.598 0.186   -0.844  1   32.09  ? 607 HOH B O   1 
HETATM 9243 O O   . HOH T 5 .   ? -26.986 9.956   -1.094  1   41.77  ? 608 HOH B O   1 
HETATM 9244 O O   . HOH T 5 .   ? -12.686 9.159   -10.124 1   32.3   ? 609 HOH B O   1 
HETATM 9245 O O   . HOH T 5 .   ? -19.614 20.587  11.827  1   46.11  ? 610 HOH B O   1 
HETATM 9246 O O   . HOH T 5 .   ? -20.067 10.341  -8.898  1   28.48  ? 611 HOH B O   1 
HETATM 9247 O O   . HOH T 5 .   ? -36.621 5.485   8.022   1   32.56  ? 612 HOH B O   1 
HETATM 9248 O O   . HOH T 5 .   ? -22.553 10.985  -12.734 1   27.04  ? 613 HOH B O   1 
HETATM 9249 O O   . HOH T 5 .   ? -8.823  2.214   16.348  1   36.48  ? 614 HOH B O   1 
HETATM 9250 O O   . HOH T 5 .   ? -27.896 -19.66  -6.137  1   37.04  ? 615 HOH B O   1 
HETATM 9251 O O   . HOH T 5 .   ? -24.407 -24.32  -4.805  1   39.89  ? 616 HOH B O   1 
HETATM 9252 O O   . HOH T 5 .   ? -14.33  -10.834 -1.117  1   32.28  ? 617 HOH B O   1 
HETATM 9253 O O   . HOH T 5 .   ? -26.781 -19.657 -9.876  1   41.79  ? 618 HOH B O   1 
HETATM 9254 O O   . HOH T 5 .   ? -30.095 11.003  13.548  1   36.42  ? 619 HOH B O   1 
HETATM 9255 O O   . HOH T 5 .   ? -16.865 -8.498  1.266   1   23.03  ? 620 HOH B O   1 
HETATM 9256 O O   . HOH T 5 .   ? -28.591 -4.122  2.92    1   37.41  ? 621 HOH B O   1 
HETATM 9257 O O   . HOH T 5 .   ? -27.486 10.453  -12.497 1   37.32  ? 622 HOH B O   1 
HETATM 9258 O O   . HOH T 5 .   ? -31.486 15.106  2.499   1   35.25  ? 623 HOH B O   1 
HETATM 9259 O O   . HOH T 5 .   ? -30.994 -19.896 -5.551  1   45.37  ? 624 HOH B O   1 
HETATM 9260 O O   . HOH T 5 .   ? -24.714 8.105   -19.148 1   36.2   ? 625 HOH B O   1 
HETATM 9261 O O   . HOH T 5 .   ? -21.825 7.779   -18.323 1   40.44  ? 626 HOH B O   1 
HETATM 9262 O O   . HOH T 5 .   ? -20.117 9.536   -11.9   1   30.35  ? 627 HOH B O   1 
HETATM 9263 O O   . HOH T 5 .   ? -17.104 -8.978  -3.904  1   52.11  ? 628 HOH B O   1 
HETATM 9264 O O   . HOH T 5 .   ? -8.338  -22.867 -7.12   1   30.7   ? 629 HOH B O   1 
HETATM 9265 O O   . HOH T 5 .   ? -23.029 2.716   -26.644 1   48.96  ? 630 HOH B O   1 
HETATM 9266 O O   . HOH T 5 .   ? -35.842 -8.79   -2.444  1   21.77  ? 631 HOH B O   1 
HETATM 9267 O O   . HOH T 5 .   ? -37.577 -3.257  -8.319  1   30.28  ? 632 HOH B O   1 
HETATM 9268 O O   . HOH T 5 .   ? -30.887 -12.604 -5.532  1   27.16  ? 633 HOH B O   1 
HETATM 9269 O O   . HOH T 5 .   ? -13.903 5.696   20.653  1   27.32  ? 634 HOH B O   1 
HETATM 9270 O O   . HOH T 5 .   ? -33.491 7.904   -10.431 1   45.05  ? 635 HOH B O   1 
HETATM 9271 O O   . HOH T 5 .   ? -33.686 7.455   1.041   1   42.83  ? 636 HOH B O   1 
HETATM 9272 O O   . HOH T 5 .   ? -29.761 -22.657 -0.309  1   35.24  ? 637 HOH B O   1 
HETATM 9273 O O   . HOH T 5 .   ? -18.995 -9.272  3.178   1   27.65  ? 638 HOH B O   1 
HETATM 9274 O O   . HOH T 5 .   ? -24.308 20.061  -0.184  1   40.83  ? 639 HOH B O   1 
HETATM 9275 O O   . HOH T 5 .   ? -17.698 -11.391 -5.352  1   33.55  ? 640 HOH B O   1 
HETATM 9276 O O   . HOH T 5 .   ? -35.415 -4.219  -2.342  1   30.87  ? 641 HOH B O   1 
HETATM 9277 O O   . HOH T 5 .   ? -29.081 -18.863 5.22    1   44.03  ? 642 HOH B O   1 
HETATM 9278 O O   . HOH T 5 .   ? -7.43   -5.902  -8.557  1   45.33  ? 643 HOH B O   1 
HETATM 9279 O O   . HOH T 5 .   ? -23.161 -28.199 -7.706  1   44.35  ? 644 HOH B O   1 
HETATM 9280 O O   . HOH T 5 .   ? -16.149 16.958  6.835   1   42.56  ? 645 HOH B O   1 
HETATM 9281 O O   . HOH T 5 .   ? -26.156 -2.312  11.881  1   37.96  ? 646 HOH B O   1 
HETATM 9282 O O   . HOH T 5 .   ? -25.952 0.864   1.618   1   43.96  ? 647 HOH B O   1 
HETATM 9283 O O   . HOH T 5 .   ? -7.349  -21.109 -10.58  1   31.93  ? 648 HOH B O   1 
HETATM 9284 O O   . HOH T 5 .   ? -24.61  -18.076 -9.712  1   40.92  ? 649 HOH B O   1 
HETATM 9285 O O   . HOH T 5 .   ? -42.448 -5.76   -16.513 1   28.22  ? 650 HOH B O   1 
HETATM 9286 O O   . HOH T 5 .   ? -32.089 10.575  -12.043 1   34.94  ? 651 HOH B O   1 
HETATM 9287 O O   . HOH T 5 .   ? -25.226 -24.815 -2.02   1   29.36  ? 652 HOH B O   1 
HETATM 9288 O O   . HOH T 5 .   ? -21.901 21.616  11.651  1   46.23  ? 653 HOH B O   1 
HETATM 9289 O O   . HOH T 5 .   ? -12.768 11.98   -9.933  1   29.18  ? 654 HOH B O   1 
HETATM 9290 O O   . HOH T 5 .   ? -23.093 -2.122  -2.081  1   25.29  ? 655 HOH B O   1 
HETATM 9291 O O   . HOH T 5 .   ? -13.684 -5.722  -5.876  1   22.45  ? 656 HOH B O   1 
HETATM 9292 O O   . HOH T 5 .   ? -17.274 -32.545 -4.104  1   30.69  ? 657 HOH B O   1 
HETATM 9293 O O   . HOH T 5 .   ? 4.599   -8.278  -2.096  1   49.29  ? 658 HOH B O   1 
HETATM 9294 O O   . HOH T 5 .   ? -30.447 16.616  0.144   1   45.16  ? 659 HOH B O   1 
HETATM 9295 O O   . HOH T 5 .   ? -29.863 15.197  16.978  1   42.96  ? 660 HOH B O   1 
HETATM 9296 O O   . HOH T 5 .   ? -22.709 10.146  -9.18   1   30.56  ? 661 HOH B O   1 
HETATM 9297 O O   . HOH T 5 .   ? -17.646 15.624  -8.09   1   40.24  ? 662 HOH B O   1 
HETATM 9298 O O   . HOH T 5 .   ? -30.589 8.631   12.791  1   29.9   ? 663 HOH B O   1 
HETATM 9299 O O   . HOH T 5 .   ? -25.036 -19.292 -17.792 1   33.46  ? 664 HOH B O   1 
HETATM 9300 O O   . HOH T 5 .   ? -23.717 -25.789 -8.982  1   28.8   ? 665 HOH B O   1 
HETATM 9301 O O   . HOH T 5 .   ? -6.688  -6.679  -2.627  1   27.2   ? 666 HOH B O   1 
HETATM 9302 O O   . HOH T 5 .   ? -26.155 16.296  14.154  1   37.9   ? 667 HOH B O   1 
HETATM 9303 O O   . HOH T 5 .   ? -31.075 -1.8    -26.507 1   41.09  ? 668 HOH B O   1 
HETATM 9304 O O   . HOH T 5 .   ? -33.451 -16.877 -3.257  1   27.09  ? 669 HOH B O   1 
HETATM 9305 O O   . HOH T 5 .   ? -27.715 -13.23  -19.702 1   44.8   ? 670 HOH B O   1 
HETATM 9306 O O   . HOH T 5 .   ? -16.899 -26.66  -3.988  1   21.63  ? 671 HOH B O   1 
HETATM 9307 O O   . HOH T 5 .   ? -24.301 -0.529  0.469   1   32.43  ? 672 HOH B O   1 
HETATM 9308 O O   . HOH T 5 .   ? -24.86  9.9     -11.939 1   33.43  ? 673 HOH B O   1 
HETATM 9309 O O   . HOH T 5 .   ? -37.929 -10.147 -2.486  1   28.96  ? 674 HOH B O   1 
HETATM 9310 O O   . HOH U 5 .   ? -42.558 37.086  28.822  1   42.08  ? 601 HOH C O   1 
HETATM 9311 O O   . HOH U 5 .   ? -45.41  23.677  16.704  1   43.88  ? 602 HOH C O   1 
HETATM 9312 O O   . HOH U 5 .   ? -41.415 4.176   37.744  1   37.76  ? 603 HOH C O   1 
HETATM 9313 O O   . HOH U 5 .   ? -43.648 6.822   44.214  1   39.01  ? 604 HOH C O   1 
HETATM 9314 O O   . HOH U 5 .   ? -23.681 0.718   47.871  1   45.61  ? 605 HOH C O   1 
HETATM 9315 O O   . HOH U 5 .   ? -37.095 6.891   23.582  1   30.09  ? 606 HOH C O   1 
HETATM 9316 O O   . HOH U 5 .   ? -54.172 1.542   40.2    1   30.99  ? 607 HOH C O   1 
HETATM 9317 O O   . HOH U 5 .   ? -29.48  15.12   20.55   1   48.86  ? 608 HOH C O   1 
HETATM 9318 O O   . HOH U 5 .   ? -51.824 23.554  36.054  1   26.27  ? 609 HOH C O   1 
HETATM 9319 O O   . HOH U 5 .   ? -38.142 7.33    18.383  1   46.36  ? 610 HOH C O   1 
HETATM 9320 O O   . HOH U 5 .   ? -37.051 30.921  31.34   1   47.12  ? 611 HOH C O   1 
HETATM 9321 O O   . HOH U 5 .   ? -38.81  7.971   21.456  1   35.27  ? 612 HOH C O   1 
HETATM 9322 O O   . HOH U 5 .   ? -49.115 12.458  35.002  1   29.55  ? 613 HOH C O   1 
HETATM 9323 O O   . HOH U 5 .   ? -38.463 28.279  34.731  1   35.24  ? 614 HOH C O   1 
HETATM 9324 O O   . HOH U 5 .   ? -57.645 3.846   17.261  1   45.3   ? 615 HOH C O   1 
HETATM 9325 O O   . HOH U 5 .   ? -23.999 10.445  20.945  1   29.08  ? 616 HOH C O   1 
HETATM 9326 O O   . HOH U 5 .   ? -30.121 12.83   18.594  1   42.87  ? 617 HOH C O   1 
HETATM 9327 O O   . HOH U 5 .   ? -23.228 0.867   23.855  1   40.88  ? 618 HOH C O   1 
HETATM 9328 O O   . HOH U 5 .   ? -48.566 10.05   16.377  1   39.35  ? 619 HOH C O   1 
HETATM 9329 O O   . HOH U 5 .   ? -34.982 13.597  32.778  1   20.38  ? 620 HOH C O   1 
HETATM 9330 O O   . HOH U 5 .   ? -54.625 -4.856  43.297  1   34.99  ? 621 HOH C O   1 
HETATM 9331 O O   . HOH U 5 .   ? -21.551 -0.026  28.457  1   37.3   ? 622 HOH C O   1 
HETATM 9332 O O   . HOH U 5 .   ? -36.113 11.219  30.5    1   23.31  ? 623 HOH C O   1 
HETATM 9333 O O   . HOH U 5 .   ? -33.502 12.204  18.272  1   35.19  ? 624 HOH C O   1 
HETATM 9334 O O   . HOH U 5 .   ? -47.534 -4.655  44.427  1   30.99  ? 625 HOH C O   1 
HETATM 9335 O O   . HOH U 5 .   ? -52.284 22.392  38.324  1   28.42  ? 626 HOH C O   1 
HETATM 9336 O O   . HOH U 5 .   ? -61.7   2.695   45.458  1   37.08  ? 627 HOH C O   1 
HETATM 9337 O O   . HOH U 5 .   ? -51.237 5.852   20.032  1   31.3   ? 628 HOH C O   1 
HETATM 9338 O O   . HOH U 5 .   ? -49.038 2.359   47.56   1   29.17  ? 629 HOH C O   1 
HETATM 9339 O O   . HOH U 5 .   ? -57.146 7.275   28.123  1   50.7   ? 630 HOH C O   1 
HETATM 9340 O O   . HOH U 5 .   ? -26.166 8.326   19.643  1   44.79  ? 631 HOH C O   1 
HETATM 9341 O O   . HOH U 5 .   ? -47.707 11.489  47.455  1   22.57  ? 632 HOH C O   1 
HETATM 9342 O O   . HOH U 5 .   ? -73.662 13.456  41.466  1   31.91  ? 633 HOH C O   1 
HETATM 9343 O O   . HOH U 5 .   ? -33.325 22.547  20.502  1   44.03  ? 634 HOH C O   1 
HETATM 9344 O O   . HOH U 5 .   ? -59.199 5.88    37.482  1   46.7   ? 635 HOH C O   1 
HETATM 9345 O O   . HOH U 5 .   ? -25.369 5.004   20.257  1   25.52  ? 636 HOH C O   1 
HETATM 9346 O O   . HOH U 5 .   ? -19.616 7.049   22.02   1   42.81  ? 637 HOH C O   1 
HETATM 9347 O O   . HOH U 5 .   ? -24.572 7.837   21.652  1   27.93  ? 638 HOH C O   1 
# 
