data_9ETA
# 
_entry.id   9ETA 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ETA         pdb_00009eta 10.2210/pdb9eta/pdb 
WWPDB D_1292137003 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ETA 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Cyclin-A2                   30817.473 2   ?         ? ? ? 
2 polymer     man 'Cyclin-dependent kinase 2' 34354.770 2   2.7.11.22 ? ? ? 
3 non-polymer syn 4-bromanyl-1,2-oxazole      147.958   2   ?         ? ? ? 
4 water       nat water                       18.015    224 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 Cyclin-A                                            
2 'Cell division protein kinase 2,p33 protein kinase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
D,B ? 
2 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 4-bromanyl-1,2-oxazole 7ZX 
4 water                  HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   VAL n 
1 3   ASN n 
1 4   GLU n 
1 5   VAL n 
1 6   PRO n 
1 7   ASP n 
1 8   TYR n 
1 9   HIS n 
1 10  GLU n 
1 11  ASP n 
1 12  ILE n 
1 13  HIS n 
1 14  THR n 
1 15  TYR n 
1 16  LEU n 
1 17  ARG n 
1 18  GLU n 
1 19  MET n 
1 20  GLU n 
1 21  VAL n 
1 22  LYS n 
1 23  CYS n 
1 24  LYS n 
1 25  PRO n 
1 26  LYS n 
1 27  VAL n 
1 28  GLY n 
1 29  TYR n 
1 30  MET n 
1 31  LYS n 
1 32  LYS n 
1 33  GLN n 
1 34  PRO n 
1 35  ASP n 
1 36  ILE n 
1 37  THR n 
1 38  ASN n 
1 39  SER n 
1 40  MET n 
1 41  ARG n 
1 42  ALA n 
1 43  ILE n 
1 44  LEU n 
1 45  VAL n 
1 46  ASP n 
1 47  TRP n 
1 48  LEU n 
1 49  VAL n 
1 50  GLU n 
1 51  VAL n 
1 52  GLY n 
1 53  GLU n 
1 54  GLU n 
1 55  TYR n 
1 56  LYS n 
1 57  LEU n 
1 58  GLN n 
1 59  ASN n 
1 60  GLU n 
1 61  THR n 
1 62  LEU n 
1 63  HIS n 
1 64  LEU n 
1 65  ALA n 
1 66  VAL n 
1 67  ASN n 
1 68  TYR n 
1 69  ILE n 
1 70  ASP n 
1 71  ARG n 
1 72  PHE n 
1 73  LEU n 
1 74  SER n 
1 75  SER n 
1 76  MET n 
1 77  SER n 
1 78  VAL n 
1 79  LEU n 
1 80  ARG n 
1 81  GLY n 
1 82  LYS n 
1 83  LEU n 
1 84  GLN n 
1 85  LEU n 
1 86  VAL n 
1 87  GLY n 
1 88  THR n 
1 89  ALA n 
1 90  ALA n 
1 91  MET n 
1 92  LEU n 
1 93  LEU n 
1 94  ALA n 
1 95  SER n 
1 96  LYS n 
1 97  PHE n 
1 98  GLU n 
1 99  GLU n 
1 100 ILE n 
1 101 TYR n 
1 102 PRO n 
1 103 PRO n 
1 104 GLU n 
1 105 VAL n 
1 106 ALA n 
1 107 GLU n 
1 108 PHE n 
1 109 VAL n 
1 110 TYR n 
1 111 ILE n 
1 112 THR n 
1 113 ASP n 
1 114 ASP n 
1 115 THR n 
1 116 TYR n 
1 117 THR n 
1 118 LYS n 
1 119 LYS n 
1 120 GLN n 
1 121 VAL n 
1 122 LEU n 
1 123 ARG n 
1 124 MET n 
1 125 GLU n 
1 126 HIS n 
1 127 LEU n 
1 128 VAL n 
1 129 LEU n 
1 130 LYS n 
1 131 VAL n 
1 132 LEU n 
1 133 ALA n 
1 134 PHE n 
1 135 ASP n 
1 136 LEU n 
1 137 ALA n 
1 138 ALA n 
1 139 PRO n 
1 140 THR n 
1 141 ILE n 
1 142 ASN n 
1 143 GLN n 
1 144 PHE n 
1 145 LEU n 
1 146 THR n 
1 147 GLN n 
1 148 TYR n 
1 149 PHE n 
1 150 LEU n 
1 151 HIS n 
1 152 GLN n 
1 153 GLN n 
1 154 PRO n 
1 155 ALA n 
1 156 ASN n 
1 157 CYS n 
1 158 LYS n 
1 159 VAL n 
1 160 GLU n 
1 161 SER n 
1 162 LEU n 
1 163 ALA n 
1 164 MET n 
1 165 PHE n 
1 166 LEU n 
1 167 GLY n 
1 168 GLU n 
1 169 LEU n 
1 170 SER n 
1 171 LEU n 
1 172 ILE n 
1 173 ASP n 
1 174 ALA n 
1 175 ASP n 
1 176 PRO n 
1 177 TYR n 
1 178 LEU n 
1 179 LYS n 
1 180 TYR n 
1 181 LEU n 
1 182 PRO n 
1 183 SER n 
1 184 VAL n 
1 185 ILE n 
1 186 ALA n 
1 187 ALA n 
1 188 ALA n 
1 189 ALA n 
1 190 PHE n 
1 191 HIS n 
1 192 LEU n 
1 193 ALA n 
1 194 LEU n 
1 195 TYR n 
1 196 THR n 
1 197 VAL n 
1 198 THR n 
1 199 GLY n 
1 200 GLN n 
1 201 SER n 
1 202 TRP n 
1 203 PRO n 
1 204 GLU n 
1 205 SER n 
1 206 LEU n 
1 207 VAL n 
1 208 GLN n 
1 209 LYS n 
1 210 THR n 
1 211 GLY n 
1 212 TYR n 
1 213 THR n 
1 214 LEU n 
1 215 GLU n 
1 216 THR n 
1 217 LEU n 
1 218 LYS n 
1 219 PRO n 
1 220 CYS n 
1 221 LEU n 
1 222 LEU n 
1 223 ASP n 
1 224 LEU n 
1 225 HIS n 
1 226 GLN n 
1 227 THR n 
1 228 TYR n 
1 229 LEU n 
1 230 ARG n 
1 231 ALA n 
1 232 PRO n 
1 233 GLN n 
1 234 HIS n 
1 235 ALA n 
1 236 GLN n 
1 237 GLN n 
1 238 SER n 
1 239 ILE n 
1 240 ARG n 
1 241 GLU n 
1 242 LYS n 
1 243 TYR n 
1 244 LYS n 
1 245 ASN n 
1 246 SER n 
1 247 LYS n 
1 248 TYR n 
1 249 HIS n 
1 250 GLY n 
1 251 VAL n 
1 252 SER n 
1 253 LEU n 
1 254 LEU n 
1 255 ASN n 
1 256 PRO n 
1 257 PRO n 
1 258 GLU n 
1 259 THR n 
1 260 LEU n 
1 261 ASN n 
1 262 VAL n 
1 263 HIS n 
1 264 HIS n 
1 265 HIS n 
1 266 HIS n 
1 267 HIS n 
1 268 HIS n 
2 1   GLY n 
2 2   PRO n 
2 3   GLY n 
2 4   SER n 
2 5   MET n 
2 6   GLU n 
2 7   ASN n 
2 8   PHE n 
2 9   GLN n 
2 10  LYS n 
2 11  VAL n 
2 12  GLU n 
2 13  LYS n 
2 14  ILE n 
2 15  GLY n 
2 16  GLU n 
2 17  GLY n 
2 18  THR n 
2 19  TYR n 
2 20  GLY n 
2 21  VAL n 
2 22  VAL n 
2 23  TYR n 
2 24  LYS n 
2 25  ALA n 
2 26  ARG n 
2 27  ASN n 
2 28  LYS n 
2 29  LEU n 
2 30  THR n 
2 31  GLY n 
2 32  GLU n 
2 33  VAL n 
2 34  VAL n 
2 35  ALA n 
2 36  LEU n 
2 37  LYS n 
2 38  LYS n 
2 39  ILE n 
2 40  ARG n 
2 41  LEU n 
2 42  ASP n 
2 43  THR n 
2 44  GLU n 
2 45  THR n 
2 46  GLU n 
2 47  GLY n 
2 48  VAL n 
2 49  PRO n 
2 50  SER n 
2 51  THR n 
2 52  ALA n 
2 53  ILE n 
2 54  ARG n 
2 55  GLU n 
2 56  ILE n 
2 57  SER n 
2 58  LEU n 
2 59  LEU n 
2 60  LYS n 
2 61  GLU n 
2 62  LEU n 
2 63  ASN n 
2 64  HIS n 
2 65  PRO n 
2 66  ASN n 
2 67  ILE n 
2 68  VAL n 
2 69  LYS n 
2 70  LEU n 
2 71  LEU n 
2 72  ASP n 
2 73  VAL n 
2 74  ILE n 
2 75  HIS n 
2 76  THR n 
2 77  GLU n 
2 78  ASN n 
2 79  LYS n 
2 80  LEU n 
2 81  TYR n 
2 82  LEU n 
2 83  VAL n 
2 84  PHE n 
2 85  GLU n 
2 86  PHE n 
2 87  LEU n 
2 88  HIS n 
2 89  GLN n 
2 90  ASP n 
2 91  LEU n 
2 92  LYS n 
2 93  LYS n 
2 94  PHE n 
2 95  MET n 
2 96  ASP n 
2 97  ALA n 
2 98  SER n 
2 99  ALA n 
2 100 LEU n 
2 101 THR n 
2 102 GLY n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 PRO n 
2 107 LEU n 
2 108 ILE n 
2 109 LYS n 
2 110 SER n 
2 111 TYR n 
2 112 LEU n 
2 113 PHE n 
2 114 GLN n 
2 115 LEU n 
2 116 LEU n 
2 117 GLN n 
2 118 GLY n 
2 119 LEU n 
2 120 ALA n 
2 121 PHE n 
2 122 CYS n 
2 123 HIS n 
2 124 SER n 
2 125 HIS n 
2 126 ARG n 
2 127 VAL n 
2 128 LEU n 
2 129 HIS n 
2 130 ARG n 
2 131 ASP n 
2 132 LEU n 
2 133 LYS n 
2 134 PRO n 
2 135 GLN n 
2 136 ASN n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ASN n 
2 141 THR n 
2 142 GLU n 
2 143 GLY n 
2 144 ALA n 
2 145 ILE n 
2 146 LYS n 
2 147 LEU n 
2 148 ALA n 
2 149 ASP n 
2 150 PHE n 
2 151 GLY n 
2 152 LEU n 
2 153 ALA n 
2 154 ARG n 
2 155 ALA n 
2 156 PHE n 
2 157 GLY n 
2 158 VAL n 
2 159 PRO n 
2 160 VAL n 
2 161 ARG n 
2 162 THR n 
2 163 TYR n 
2 164 TPO n 
2 165 HIS n 
2 166 GLU n 
2 167 VAL n 
2 168 VAL n 
2 169 THR n 
2 170 LEU n 
2 171 TRP n 
2 172 TYR n 
2 173 ARG n 
2 174 ALA n 
2 175 PRO n 
2 176 GLU n 
2 177 ILE n 
2 178 LEU n 
2 179 LEU n 
2 180 GLY n 
2 181 CYS n 
2 182 LYS n 
2 183 TYR n 
2 184 TYR n 
2 185 SER n 
2 186 THR n 
2 187 ALA n 
2 188 VAL n 
2 189 ASP n 
2 190 ILE n 
2 191 TRP n 
2 192 SER n 
2 193 LEU n 
2 194 GLY n 
2 195 CYS n 
2 196 ILE n 
2 197 PHE n 
2 198 ALA n 
2 199 GLU n 
2 200 MET n 
2 201 VAL n 
2 202 THR n 
2 203 ARG n 
2 204 ARG n 
2 205 ALA n 
2 206 LEU n 
2 207 PHE n 
2 208 PRO n 
2 209 GLY n 
2 210 ASP n 
2 211 SER n 
2 212 GLU n 
2 213 ILE n 
2 214 ASP n 
2 215 GLN n 
2 216 LEU n 
2 217 PHE n 
2 218 ARG n 
2 219 ILE n 
2 220 PHE n 
2 221 ARG n 
2 222 THR n 
2 223 LEU n 
2 224 GLY n 
2 225 THR n 
2 226 PRO n 
2 227 ASP n 
2 228 GLU n 
2 229 VAL n 
2 230 VAL n 
2 231 TRP n 
2 232 PRO n 
2 233 GLY n 
2 234 VAL n 
2 235 THR n 
2 236 SER n 
2 237 MET n 
2 238 PRO n 
2 239 ASP n 
2 240 TYR n 
2 241 LYS n 
2 242 PRO n 
2 243 SER n 
2 244 PHE n 
2 245 PRO n 
2 246 LYS n 
2 247 TRP n 
2 248 ALA n 
2 249 ARG n 
2 250 GLN n 
2 251 ASP n 
2 252 PHE n 
2 253 SER n 
2 254 LYS n 
2 255 VAL n 
2 256 VAL n 
2 257 PRO n 
2 258 PRO n 
2 259 LEU n 
2 260 ASP n 
2 261 GLU n 
2 262 ASP n 
2 263 GLY n 
2 264 ARG n 
2 265 SER n 
2 266 LEU n 
2 267 LEU n 
2 268 SER n 
2 269 GLN n 
2 270 MET n 
2 271 LEU n 
2 272 HIS n 
2 273 TYR n 
2 274 ASP n 
2 275 PRO n 
2 276 ASN n 
2 277 LYS n 
2 278 ARG n 
2 279 ILE n 
2 280 SER n 
2 281 ALA n 
2 282 LYS n 
2 283 ALA n 
2 284 ALA n 
2 285 LEU n 
2 286 ALA n 
2 287 HIS n 
2 288 PRO n 
2 289 PHE n 
2 290 PHE n 
2 291 GLN n 
2 292 ASP n 
2 293 VAL n 
2 294 THR n 
2 295 LYS n 
2 296 PRO n 
2 297 VAL n 
2 298 PRO n 
2 299 HIS n 
2 300 LEU n 
2 301 ARG n 
2 302 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
2 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
7ZX non-polymer         . 4-bromanyl-1,2-oxazole ?                  'C3 H2 Br N O'   147.958 
ALA 'L-peptide linking' y ALANINE                ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE               ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE             ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'        ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE               ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE              ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'        ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE              ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                  ?                  'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE             ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                 ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE             ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE          ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                 ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE              ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE       PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN             ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE               ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                 ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   171 171 GLY GLY D . n 
A 1 2   VAL 2   172 172 VAL VAL D . n 
A 1 3   ASN 3   173 173 ASN ASN D . n 
A 1 4   GLU 4   174 174 GLU GLU D . n 
A 1 5   VAL 5   175 175 VAL VAL D . n 
A 1 6   PRO 6   176 176 PRO PRO D . n 
A 1 7   ASP 7   177 177 ASP ASP D . n 
A 1 8   TYR 8   178 178 TYR TYR D . n 
A 1 9   HIS 9   179 179 HIS HIS D . n 
A 1 10  GLU 10  180 180 GLU GLU D . n 
A 1 11  ASP 11  181 181 ASP ASP D . n 
A 1 12  ILE 12  182 182 ILE ILE D . n 
A 1 13  HIS 13  183 183 HIS HIS D . n 
A 1 14  THR 14  184 184 THR THR D . n 
A 1 15  TYR 15  185 185 TYR TYR D . n 
A 1 16  LEU 16  186 186 LEU LEU D . n 
A 1 17  ARG 17  187 187 ARG ARG D . n 
A 1 18  GLU 18  188 188 GLU GLU D . n 
A 1 19  MET 19  189 189 MET MET D . n 
A 1 20  GLU 20  190 190 GLU GLU D . n 
A 1 21  VAL 21  191 191 VAL VAL D . n 
A 1 22  LYS 22  192 192 LYS LYS D . n 
A 1 23  CYS 23  193 193 CYS CYS D . n 
A 1 24  LYS 24  194 194 LYS LYS D . n 
A 1 25  PRO 25  195 195 PRO PRO D . n 
A 1 26  LYS 26  196 196 LYS LYS D . n 
A 1 27  VAL 27  197 197 VAL VAL D . n 
A 1 28  GLY 28  198 198 GLY GLY D . n 
A 1 29  TYR 29  199 199 TYR TYR D . n 
A 1 30  MET 30  200 200 MET MET D . n 
A 1 31  LYS 31  201 201 LYS LYS D . n 
A 1 32  LYS 32  202 202 LYS LYS D . n 
A 1 33  GLN 33  203 203 GLN GLN D . n 
A 1 34  PRO 34  204 204 PRO PRO D . n 
A 1 35  ASP 35  205 205 ASP ASP D . n 
A 1 36  ILE 36  206 206 ILE ILE D . n 
A 1 37  THR 37  207 207 THR THR D . n 
A 1 38  ASN 38  208 208 ASN ASN D . n 
A 1 39  SER 39  209 209 SER SER D . n 
A 1 40  MET 40  210 210 MET MET D . n 
A 1 41  ARG 41  211 211 ARG ARG D . n 
A 1 42  ALA 42  212 212 ALA ALA D . n 
A 1 43  ILE 43  213 213 ILE ILE D . n 
A 1 44  LEU 44  214 214 LEU LEU D . n 
A 1 45  VAL 45  215 215 VAL VAL D . n 
A 1 46  ASP 46  216 216 ASP ASP D . n 
A 1 47  TRP 47  217 217 TRP TRP D . n 
A 1 48  LEU 48  218 218 LEU LEU D . n 
A 1 49  VAL 49  219 219 VAL VAL D . n 
A 1 50  GLU 50  220 220 GLU GLU D . n 
A 1 51  VAL 51  221 221 VAL VAL D . n 
A 1 52  GLY 52  222 222 GLY GLY D . n 
A 1 53  GLU 53  223 223 GLU GLU D . n 
A 1 54  GLU 54  224 224 GLU GLU D . n 
A 1 55  TYR 55  225 225 TYR TYR D . n 
A 1 56  LYS 56  226 226 LYS LYS D . n 
A 1 57  LEU 57  227 227 LEU LEU D . n 
A 1 58  GLN 58  228 228 GLN GLN D . n 
A 1 59  ASN 59  229 229 ASN ASN D . n 
A 1 60  GLU 60  230 230 GLU GLU D . n 
A 1 61  THR 61  231 231 THR THR D . n 
A 1 62  LEU 62  232 232 LEU LEU D . n 
A 1 63  HIS 63  233 233 HIS HIS D . n 
A 1 64  LEU 64  234 234 LEU LEU D . n 
A 1 65  ALA 65  235 235 ALA ALA D . n 
A 1 66  VAL 66  236 236 VAL VAL D . n 
A 1 67  ASN 67  237 237 ASN ASN D . n 
A 1 68  TYR 68  238 238 TYR TYR D . n 
A 1 69  ILE 69  239 239 ILE ILE D . n 
A 1 70  ASP 70  240 240 ASP ASP D . n 
A 1 71  ARG 71  241 241 ARG ARG D . n 
A 1 72  PHE 72  242 242 PHE PHE D . n 
A 1 73  LEU 73  243 243 LEU LEU D . n 
A 1 74  SER 74  244 244 SER SER D . n 
A 1 75  SER 75  245 245 SER SER D . n 
A 1 76  MET 76  246 246 MET MET D . n 
A 1 77  SER 77  247 247 SER SER D . n 
A 1 78  VAL 78  248 248 VAL VAL D . n 
A 1 79  LEU 79  249 249 LEU LEU D . n 
A 1 80  ARG 80  250 250 ARG ARG D . n 
A 1 81  GLY 81  251 251 GLY GLY D . n 
A 1 82  LYS 82  252 252 LYS LYS D . n 
A 1 83  LEU 83  253 253 LEU LEU D . n 
A 1 84  GLN 84  254 254 GLN GLN D . n 
A 1 85  LEU 85  255 255 LEU LEU D . n 
A 1 86  VAL 86  256 256 VAL VAL D . n 
A 1 87  GLY 87  257 257 GLY GLY D . n 
A 1 88  THR 88  258 258 THR THR D . n 
A 1 89  ALA 89  259 259 ALA ALA D . n 
A 1 90  ALA 90  260 260 ALA ALA D . n 
A 1 91  MET 91  261 261 MET MET D . n 
A 1 92  LEU 92  262 262 LEU LEU D . n 
A 1 93  LEU 93  263 263 LEU LEU D . n 
A 1 94  ALA 94  264 264 ALA ALA D . n 
A 1 95  SER 95  265 265 SER SER D . n 
A 1 96  LYS 96  266 266 LYS LYS D . n 
A 1 97  PHE 97  267 267 PHE PHE D . n 
A 1 98  GLU 98  268 268 GLU GLU D . n 
A 1 99  GLU 99  269 269 GLU GLU D . n 
A 1 100 ILE 100 270 270 ILE ILE D . n 
A 1 101 TYR 101 271 271 TYR TYR D . n 
A 1 102 PRO 102 272 272 PRO PRO D . n 
A 1 103 PRO 103 273 273 PRO PRO D . n 
A 1 104 GLU 104 274 274 GLU GLU D . n 
A 1 105 VAL 105 275 275 VAL VAL D . n 
A 1 106 ALA 106 276 276 ALA ALA D . n 
A 1 107 GLU 107 277 277 GLU GLU D . n 
A 1 108 PHE 108 278 278 PHE PHE D . n 
A 1 109 VAL 109 279 279 VAL VAL D . n 
A 1 110 TYR 110 280 280 TYR TYR D . n 
A 1 111 ILE 111 281 281 ILE ILE D . n 
A 1 112 THR 112 282 282 THR THR D . n 
A 1 113 ASP 113 283 283 ASP ASP D . n 
A 1 114 ASP 114 284 284 ASP ASP D . n 
A 1 115 THR 115 285 285 THR THR D . n 
A 1 116 TYR 116 286 286 TYR TYR D . n 
A 1 117 THR 117 287 287 THR THR D . n 
A 1 118 LYS 118 288 288 LYS LYS D . n 
A 1 119 LYS 119 289 289 LYS LYS D . n 
A 1 120 GLN 120 290 290 GLN GLN D . n 
A 1 121 VAL 121 291 291 VAL VAL D . n 
A 1 122 LEU 122 292 292 LEU LEU D . n 
A 1 123 ARG 123 293 293 ARG ARG D . n 
A 1 124 MET 124 294 294 MET MET D . n 
A 1 125 GLU 125 295 295 GLU GLU D . n 
A 1 126 HIS 126 296 296 HIS HIS D . n 
A 1 127 LEU 127 297 297 LEU LEU D . n 
A 1 128 VAL 128 298 298 VAL VAL D . n 
A 1 129 LEU 129 299 299 LEU LEU D . n 
A 1 130 LYS 130 300 300 LYS LYS D . n 
A 1 131 VAL 131 301 301 VAL VAL D . n 
A 1 132 LEU 132 302 302 LEU LEU D . n 
A 1 133 ALA 133 303 303 ALA ALA D . n 
A 1 134 PHE 134 304 304 PHE PHE D . n 
A 1 135 ASP 135 305 305 ASP ASP D . n 
A 1 136 LEU 136 306 306 LEU LEU D . n 
A 1 137 ALA 137 307 307 ALA ALA D . n 
A 1 138 ALA 138 308 308 ALA ALA D . n 
A 1 139 PRO 139 309 309 PRO PRO D . n 
A 1 140 THR 140 310 310 THR THR D . n 
A 1 141 ILE 141 311 311 ILE ILE D . n 
A 1 142 ASN 142 312 312 ASN ASN D . n 
A 1 143 GLN 143 313 313 GLN GLN D . n 
A 1 144 PHE 144 314 314 PHE PHE D . n 
A 1 145 LEU 145 315 315 LEU LEU D . n 
A 1 146 THR 146 316 316 THR THR D . n 
A 1 147 GLN 147 317 317 GLN GLN D . n 
A 1 148 TYR 148 318 318 TYR TYR D . n 
A 1 149 PHE 149 319 319 PHE PHE D . n 
A 1 150 LEU 150 320 320 LEU LEU D . n 
A 1 151 HIS 151 321 321 HIS HIS D . n 
A 1 152 GLN 152 322 322 GLN GLN D . n 
A 1 153 GLN 153 323 323 GLN GLN D . n 
A 1 154 PRO 154 324 324 PRO PRO D . n 
A 1 155 ALA 155 325 325 ALA ALA D . n 
A 1 156 ASN 156 326 326 ASN ASN D . n 
A 1 157 CYS 157 327 327 CYS CYS D . n 
A 1 158 LYS 158 328 328 LYS LYS D . n 
A 1 159 VAL 159 329 329 VAL VAL D . n 
A 1 160 GLU 160 330 330 GLU GLU D . n 
A 1 161 SER 161 331 331 SER SER D . n 
A 1 162 LEU 162 332 332 LEU LEU D . n 
A 1 163 ALA 163 333 333 ALA ALA D . n 
A 1 164 MET 164 334 334 MET MET D . n 
A 1 165 PHE 165 335 335 PHE PHE D . n 
A 1 166 LEU 166 336 336 LEU LEU D . n 
A 1 167 GLY 167 337 337 GLY GLY D . n 
A 1 168 GLU 168 338 338 GLU GLU D . n 
A 1 169 LEU 169 339 339 LEU LEU D . n 
A 1 170 SER 170 340 340 SER SER D . n 
A 1 171 LEU 171 341 341 LEU LEU D . n 
A 1 172 ILE 172 342 342 ILE ILE D . n 
A 1 173 ASP 173 343 343 ASP ASP D . n 
A 1 174 ALA 174 344 344 ALA ALA D . n 
A 1 175 ASP 175 345 345 ASP ASP D . n 
A 1 176 PRO 176 346 346 PRO PRO D . n 
A 1 177 TYR 177 347 347 TYR TYR D . n 
A 1 178 LEU 178 348 348 LEU LEU D . n 
A 1 179 LYS 179 349 349 LYS LYS D . n 
A 1 180 TYR 180 350 350 TYR TYR D . n 
A 1 181 LEU 181 351 351 LEU LEU D . n 
A 1 182 PRO 182 352 352 PRO PRO D . n 
A 1 183 SER 183 353 353 SER SER D . n 
A 1 184 VAL 184 354 354 VAL VAL D . n 
A 1 185 ILE 185 355 355 ILE ILE D . n 
A 1 186 ALA 186 356 356 ALA ALA D . n 
A 1 187 ALA 187 357 357 ALA ALA D . n 
A 1 188 ALA 188 358 358 ALA ALA D . n 
A 1 189 ALA 189 359 359 ALA ALA D . n 
A 1 190 PHE 190 360 360 PHE PHE D . n 
A 1 191 HIS 191 361 361 HIS HIS D . n 
A 1 192 LEU 192 362 362 LEU LEU D . n 
A 1 193 ALA 193 363 363 ALA ALA D . n 
A 1 194 LEU 194 364 364 LEU LEU D . n 
A 1 195 TYR 195 365 365 TYR TYR D . n 
A 1 196 THR 196 366 366 THR THR D . n 
A 1 197 VAL 197 367 367 VAL VAL D . n 
A 1 198 THR 198 368 368 THR THR D . n 
A 1 199 GLY 199 369 369 GLY GLY D . n 
A 1 200 GLN 200 370 370 GLN GLN D . n 
A 1 201 SER 201 371 371 SER SER D . n 
A 1 202 TRP 202 372 372 TRP TRP D . n 
A 1 203 PRO 203 373 373 PRO PRO D . n 
A 1 204 GLU 204 374 374 GLU GLU D . n 
A 1 205 SER 205 375 375 SER SER D . n 
A 1 206 LEU 206 376 376 LEU LEU D . n 
A 1 207 VAL 207 377 377 VAL VAL D . n 
A 1 208 GLN 208 378 378 GLN GLN D . n 
A 1 209 LYS 209 379 379 LYS LYS D . n 
A 1 210 THR 210 380 380 THR THR D . n 
A 1 211 GLY 211 381 381 GLY GLY D . n 
A 1 212 TYR 212 382 382 TYR TYR D . n 
A 1 213 THR 213 383 383 THR THR D . n 
A 1 214 LEU 214 384 384 LEU LEU D . n 
A 1 215 GLU 215 385 385 GLU GLU D . n 
A 1 216 THR 216 386 386 THR THR D . n 
A 1 217 LEU 217 387 387 LEU LEU D . n 
A 1 218 LYS 218 388 388 LYS LYS D . n 
A 1 219 PRO 219 389 389 PRO PRO D . n 
A 1 220 CYS 220 390 390 CYS CYS D . n 
A 1 221 LEU 221 391 391 LEU LEU D . n 
A 1 222 LEU 222 392 392 LEU LEU D . n 
A 1 223 ASP 223 393 393 ASP ASP D . n 
A 1 224 LEU 224 394 394 LEU LEU D . n 
A 1 225 HIS 225 395 395 HIS HIS D . n 
A 1 226 GLN 226 396 396 GLN GLN D . n 
A 1 227 THR 227 397 397 THR THR D . n 
A 1 228 TYR 228 398 398 TYR TYR D . n 
A 1 229 LEU 229 399 399 LEU LEU D . n 
A 1 230 ARG 230 400 400 ARG ARG D . n 
A 1 231 ALA 231 401 401 ALA ALA D . n 
A 1 232 PRO 232 402 402 PRO PRO D . n 
A 1 233 GLN 233 403 403 GLN GLN D . n 
A 1 234 HIS 234 404 404 HIS HIS D . n 
A 1 235 ALA 235 405 405 ALA ALA D . n 
A 1 236 GLN 236 406 406 GLN GLN D . n 
A 1 237 GLN 237 407 407 GLN GLN D . n 
A 1 238 SER 238 408 408 SER SER D . n 
A 1 239 ILE 239 409 409 ILE ILE D . n 
A 1 240 ARG 240 410 410 ARG ARG D . n 
A 1 241 GLU 241 411 411 GLU GLU D . n 
A 1 242 LYS 242 412 412 LYS LYS D . n 
A 1 243 TYR 243 413 413 TYR TYR D . n 
A 1 244 LYS 244 414 414 LYS LYS D . n 
A 1 245 ASN 245 415 415 ASN ASN D . n 
A 1 246 SER 246 416 416 SER SER D . n 
A 1 247 LYS 247 417 417 LYS LYS D . n 
A 1 248 TYR 248 418 418 TYR TYR D . n 
A 1 249 HIS 249 419 419 HIS HIS D . n 
A 1 250 GLY 250 420 420 GLY GLY D . n 
A 1 251 VAL 251 421 421 VAL VAL D . n 
A 1 252 SER 252 422 422 SER SER D . n 
A 1 253 LEU 253 423 423 LEU LEU D . n 
A 1 254 LEU 254 424 424 LEU LEU D . n 
A 1 255 ASN 255 425 425 ASN ASN D . n 
A 1 256 PRO 256 426 426 PRO PRO D . n 
A 1 257 PRO 257 427 427 PRO PRO D . n 
A 1 258 GLU 258 428 428 GLU GLU D . n 
A 1 259 THR 259 429 429 THR THR D . n 
A 1 260 LEU 260 430 430 LEU LEU D . n 
A 1 261 ASN 261 431 431 ASN ASN D . n 
A 1 262 VAL 262 432 ?   ?   ?   D . n 
A 1 263 HIS 263 433 ?   ?   ?   D . n 
A 1 264 HIS 264 434 ?   ?   ?   D . n 
A 1 265 HIS 265 435 ?   ?   ?   D . n 
A 1 266 HIS 266 436 ?   ?   ?   D . n 
A 1 267 HIS 267 437 ?   ?   ?   D . n 
A 1 268 HIS 268 438 ?   ?   ?   D . n 
B 2 1   GLY 1   -3  -3  GLY GLY A . n 
B 2 2   PRO 2   -2  -2  PRO PRO A . n 
B 2 3   GLY 3   -1  -1  GLY GLY A . n 
B 2 4   SER 4   0   0   SER SER A . n 
B 2 5   MET 5   1   1   MET MET A . n 
B 2 6   GLU 6   2   2   GLU GLU A . n 
B 2 7   ASN 7   3   3   ASN ASN A . n 
B 2 8   PHE 8   4   4   PHE PHE A . n 
B 2 9   GLN 9   5   5   GLN GLN A . n 
B 2 10  LYS 10  6   6   LYS LYS A . n 
B 2 11  VAL 11  7   7   VAL VAL A . n 
B 2 12  GLU 12  8   8   GLU GLU A . n 
B 2 13  LYS 13  9   9   LYS LYS A . n 
B 2 14  ILE 14  10  10  ILE ILE A . n 
B 2 15  GLY 15  11  11  GLY GLY A . n 
B 2 16  GLU 16  12  12  GLU GLU A . n 
B 2 17  GLY 17  13  13  GLY GLY A . n 
B 2 18  THR 18  14  14  THR THR A . n 
B 2 19  TYR 19  15  15  TYR TYR A . n 
B 2 20  GLY 20  16  16  GLY GLY A . n 
B 2 21  VAL 21  17  17  VAL VAL A . n 
B 2 22  VAL 22  18  18  VAL VAL A . n 
B 2 23  TYR 23  19  19  TYR TYR A . n 
B 2 24  LYS 24  20  20  LYS LYS A . n 
B 2 25  ALA 25  21  21  ALA ALA A . n 
B 2 26  ARG 26  22  22  ARG ARG A . n 
B 2 27  ASN 27  23  23  ASN ASN A . n 
B 2 28  LYS 28  24  24  LYS LYS A . n 
B 2 29  LEU 29  25  25  LEU LEU A . n 
B 2 30  THR 30  26  26  THR THR A . n 
B 2 31  GLY 31  27  27  GLY GLY A . n 
B 2 32  GLU 32  28  28  GLU GLU A . n 
B 2 33  VAL 33  29  29  VAL VAL A . n 
B 2 34  VAL 34  30  30  VAL VAL A . n 
B 2 35  ALA 35  31  31  ALA ALA A . n 
B 2 36  LEU 36  32  32  LEU LEU A . n 
B 2 37  LYS 37  33  33  LYS LYS A . n 
B 2 38  LYS 38  34  34  LYS LYS A . n 
B 2 39  ILE 39  35  35  ILE ILE A . n 
B 2 40  ARG 40  36  36  ARG ARG A . n 
B 2 41  LEU 41  37  37  LEU LEU A . n 
B 2 42  ASP 42  38  38  ASP ASP A . n 
B 2 43  THR 43  39  39  THR THR A . n 
B 2 44  GLU 44  40  40  GLU GLU A . n 
B 2 45  THR 45  41  41  THR THR A . n 
B 2 46  GLU 46  42  42  GLU GLU A . n 
B 2 47  GLY 47  43  43  GLY GLY A . n 
B 2 48  VAL 48  44  44  VAL VAL A . n 
B 2 49  PRO 49  45  45  PRO PRO A . n 
B 2 50  SER 50  46  46  SER SER A . n 
B 2 51  THR 51  47  47  THR THR A . n 
B 2 52  ALA 52  48  48  ALA ALA A . n 
B 2 53  ILE 53  49  49  ILE ILE A . n 
B 2 54  ARG 54  50  50  ARG ARG A . n 
B 2 55  GLU 55  51  51  GLU GLU A . n 
B 2 56  ILE 56  52  52  ILE ILE A . n 
B 2 57  SER 57  53  53  SER SER A . n 
B 2 58  LEU 58  54  54  LEU LEU A . n 
B 2 59  LEU 59  55  55  LEU LEU A . n 
B 2 60  LYS 60  56  56  LYS LYS A . n 
B 2 61  GLU 61  57  57  GLU GLU A . n 
B 2 62  LEU 62  58  58  LEU LEU A . n 
B 2 63  ASN 63  59  59  ASN ASN A . n 
B 2 64  HIS 64  60  60  HIS HIS A . n 
B 2 65  PRO 65  61  61  PRO PRO A . n 
B 2 66  ASN 66  62  62  ASN ASN A . n 
B 2 67  ILE 67  63  63  ILE ILE A . n 
B 2 68  VAL 68  64  64  VAL VAL A . n 
B 2 69  LYS 69  65  65  LYS LYS A . n 
B 2 70  LEU 70  66  66  LEU LEU A . n 
B 2 71  LEU 71  67  67  LEU LEU A . n 
B 2 72  ASP 72  68  68  ASP ASP A . n 
B 2 73  VAL 73  69  69  VAL VAL A . n 
B 2 74  ILE 74  70  70  ILE ILE A . n 
B 2 75  HIS 75  71  71  HIS HIS A . n 
B 2 76  THR 76  72  72  THR THR A . n 
B 2 77  GLU 77  73  73  GLU GLU A . n 
B 2 78  ASN 78  74  74  ASN ASN A . n 
B 2 79  LYS 79  75  75  LYS LYS A . n 
B 2 80  LEU 80  76  76  LEU LEU A . n 
B 2 81  TYR 81  77  77  TYR TYR A . n 
B 2 82  LEU 82  78  78  LEU LEU A . n 
B 2 83  VAL 83  79  79  VAL VAL A . n 
B 2 84  PHE 84  80  80  PHE PHE A . n 
B 2 85  GLU 85  81  81  GLU GLU A . n 
B 2 86  PHE 86  82  82  PHE PHE A . n 
B 2 87  LEU 87  83  83  LEU LEU A . n 
B 2 88  HIS 88  84  84  HIS HIS A . n 
B 2 89  GLN 89  85  85  GLN GLN A . n 
B 2 90  ASP 90  86  86  ASP ASP A . n 
B 2 91  LEU 91  87  87  LEU LEU A . n 
B 2 92  LYS 92  88  88  LYS LYS A . n 
B 2 93  LYS 93  89  89  LYS LYS A . n 
B 2 94  PHE 94  90  90  PHE PHE A . n 
B 2 95  MET 95  91  91  MET MET A . n 
B 2 96  ASP 96  92  92  ASP ASP A . n 
B 2 97  ALA 97  93  93  ALA ALA A . n 
B 2 98  SER 98  94  94  SER SER A . n 
B 2 99  ALA 99  95  95  ALA ALA A . n 
B 2 100 LEU 100 96  96  LEU LEU A . n 
B 2 101 THR 101 97  97  THR THR A . n 
B 2 102 GLY 102 98  98  GLY GLY A . n 
B 2 103 ILE 103 99  99  ILE ILE A . n 
B 2 104 PRO 104 100 100 PRO PRO A . n 
B 2 105 LEU 105 101 101 LEU LEU A . n 
B 2 106 PRO 106 102 102 PRO PRO A . n 
B 2 107 LEU 107 103 103 LEU LEU A . n 
B 2 108 ILE 108 104 104 ILE ILE A . n 
B 2 109 LYS 109 105 105 LYS LYS A . n 
B 2 110 SER 110 106 106 SER SER A . n 
B 2 111 TYR 111 107 107 TYR TYR A . n 
B 2 112 LEU 112 108 108 LEU LEU A . n 
B 2 113 PHE 113 109 109 PHE PHE A . n 
B 2 114 GLN 114 110 110 GLN GLN A . n 
B 2 115 LEU 115 111 111 LEU LEU A . n 
B 2 116 LEU 116 112 112 LEU LEU A . n 
B 2 117 GLN 117 113 113 GLN GLN A . n 
B 2 118 GLY 118 114 114 GLY GLY A . n 
B 2 119 LEU 119 115 115 LEU LEU A . n 
B 2 120 ALA 120 116 116 ALA ALA A . n 
B 2 121 PHE 121 117 117 PHE PHE A . n 
B 2 122 CYS 122 118 118 CYS CYS A . n 
B 2 123 HIS 123 119 119 HIS HIS A . n 
B 2 124 SER 124 120 120 SER SER A . n 
B 2 125 HIS 125 121 121 HIS HIS A . n 
B 2 126 ARG 126 122 122 ARG ARG A . n 
B 2 127 VAL 127 123 123 VAL VAL A . n 
B 2 128 LEU 128 124 124 LEU LEU A . n 
B 2 129 HIS 129 125 125 HIS HIS A . n 
B 2 130 ARG 130 126 126 ARG ARG A . n 
B 2 131 ASP 131 127 127 ASP ASP A . n 
B 2 132 LEU 132 128 128 LEU LEU A . n 
B 2 133 LYS 133 129 129 LYS LYS A . n 
B 2 134 PRO 134 130 130 PRO PRO A . n 
B 2 135 GLN 135 131 131 GLN GLN A . n 
B 2 136 ASN 136 132 132 ASN ASN A . n 
B 2 137 LEU 137 133 133 LEU LEU A . n 
B 2 138 LEU 138 134 134 LEU LEU A . n 
B 2 139 ILE 139 135 135 ILE ILE A . n 
B 2 140 ASN 140 136 136 ASN ASN A . n 
B 2 141 THR 141 137 137 THR THR A . n 
B 2 142 GLU 142 138 138 GLU GLU A . n 
B 2 143 GLY 143 139 139 GLY GLY A . n 
B 2 144 ALA 144 140 140 ALA ALA A . n 
B 2 145 ILE 145 141 141 ILE ILE A . n 
B 2 146 LYS 146 142 142 LYS LYS A . n 
B 2 147 LEU 147 143 143 LEU LEU A . n 
B 2 148 ALA 148 144 144 ALA ALA A . n 
B 2 149 ASP 149 145 145 ASP ASP A . n 
B 2 150 PHE 150 146 146 PHE PHE A . n 
B 2 151 GLY 151 147 147 GLY GLY A . n 
B 2 152 LEU 152 148 148 LEU LEU A . n 
B 2 153 ALA 153 149 149 ALA ALA A . n 
B 2 154 ARG 154 150 150 ARG ARG A . n 
B 2 155 ALA 155 151 151 ALA ALA A . n 
B 2 156 PHE 156 152 152 PHE PHE A . n 
B 2 157 GLY 157 153 153 GLY GLY A . n 
B 2 158 VAL 158 154 154 VAL VAL A . n 
B 2 159 PRO 159 155 155 PRO PRO A . n 
B 2 160 VAL 160 156 156 VAL VAL A . n 
B 2 161 ARG 161 157 157 ARG ARG A . n 
B 2 162 THR 162 158 158 THR THR A . n 
B 2 163 TYR 163 159 159 TYR TYR A . n 
B 2 164 TPO 164 160 160 TPO TPO A . n 
B 2 165 HIS 165 161 161 HIS HIS A . n 
B 2 166 GLU 166 162 162 GLU GLU A . n 
B 2 167 VAL 167 163 163 VAL VAL A . n 
B 2 168 VAL 168 164 164 VAL VAL A . n 
B 2 169 THR 169 165 165 THR THR A . n 
B 2 170 LEU 170 166 166 LEU LEU A . n 
B 2 171 TRP 171 167 167 TRP TRP A . n 
B 2 172 TYR 172 168 168 TYR TYR A . n 
B 2 173 ARG 173 169 169 ARG ARG A . n 
B 2 174 ALA 174 170 170 ALA ALA A . n 
B 2 175 PRO 175 171 171 PRO PRO A . n 
B 2 176 GLU 176 172 172 GLU GLU A . n 
B 2 177 ILE 177 173 173 ILE ILE A . n 
B 2 178 LEU 178 174 174 LEU LEU A . n 
B 2 179 LEU 179 175 175 LEU LEU A . n 
B 2 180 GLY 180 176 176 GLY GLY A . n 
B 2 181 CYS 181 177 177 CYS CYS A . n 
B 2 182 LYS 182 178 178 LYS LYS A . n 
B 2 183 TYR 183 179 179 TYR TYR A . n 
B 2 184 TYR 184 180 180 TYR TYR A . n 
B 2 185 SER 185 181 181 SER SER A . n 
B 2 186 THR 186 182 182 THR THR A . n 
B 2 187 ALA 187 183 183 ALA ALA A . n 
B 2 188 VAL 188 184 184 VAL VAL A . n 
B 2 189 ASP 189 185 185 ASP ASP A . n 
B 2 190 ILE 190 186 186 ILE ILE A . n 
B 2 191 TRP 191 187 187 TRP TRP A . n 
B 2 192 SER 192 188 188 SER SER A . n 
B 2 193 LEU 193 189 189 LEU LEU A . n 
B 2 194 GLY 194 190 190 GLY GLY A . n 
B 2 195 CYS 195 191 191 CYS CYS A . n 
B 2 196 ILE 196 192 192 ILE ILE A . n 
B 2 197 PHE 197 193 193 PHE PHE A . n 
B 2 198 ALA 198 194 194 ALA ALA A . n 
B 2 199 GLU 199 195 195 GLU GLU A . n 
B 2 200 MET 200 196 196 MET MET A . n 
B 2 201 VAL 201 197 197 VAL VAL A . n 
B 2 202 THR 202 198 198 THR THR A . n 
B 2 203 ARG 203 199 199 ARG ARG A . n 
B 2 204 ARG 204 200 200 ARG ARG A . n 
B 2 205 ALA 205 201 201 ALA ALA A . n 
B 2 206 LEU 206 202 202 LEU LEU A . n 
B 2 207 PHE 207 203 203 PHE PHE A . n 
B 2 208 PRO 208 204 204 PRO PRO A . n 
B 2 209 GLY 209 205 205 GLY GLY A . n 
B 2 210 ASP 210 206 206 ASP ASP A . n 
B 2 211 SER 211 207 207 SER SER A . n 
B 2 212 GLU 212 208 208 GLU GLU A . n 
B 2 213 ILE 213 209 209 ILE ILE A . n 
B 2 214 ASP 214 210 210 ASP ASP A . n 
B 2 215 GLN 215 211 211 GLN GLN A . n 
B 2 216 LEU 216 212 212 LEU LEU A . n 
B 2 217 PHE 217 213 213 PHE PHE A . n 
B 2 218 ARG 218 214 214 ARG ARG A . n 
B 2 219 ILE 219 215 215 ILE ILE A . n 
B 2 220 PHE 220 216 216 PHE PHE A . n 
B 2 221 ARG 221 217 217 ARG ARG A . n 
B 2 222 THR 222 218 218 THR THR A . n 
B 2 223 LEU 223 219 219 LEU LEU A . n 
B 2 224 GLY 224 220 220 GLY GLY A . n 
B 2 225 THR 225 221 221 THR THR A . n 
B 2 226 PRO 226 222 222 PRO PRO A . n 
B 2 227 ASP 227 223 223 ASP ASP A . n 
B 2 228 GLU 228 224 224 GLU GLU A . n 
B 2 229 VAL 229 225 225 VAL VAL A . n 
B 2 230 VAL 230 226 226 VAL VAL A . n 
B 2 231 TRP 231 227 227 TRP TRP A . n 
B 2 232 PRO 232 228 228 PRO PRO A . n 
B 2 233 GLY 233 229 229 GLY GLY A . n 
B 2 234 VAL 234 230 230 VAL VAL A . n 
B 2 235 THR 235 231 231 THR THR A . n 
B 2 236 SER 236 232 232 SER SER A . n 
B 2 237 MET 237 233 233 MET MET A . n 
B 2 238 PRO 238 234 234 PRO PRO A . n 
B 2 239 ASP 239 235 235 ASP ASP A . n 
B 2 240 TYR 240 236 236 TYR TYR A . n 
B 2 241 LYS 241 237 237 LYS LYS A . n 
B 2 242 PRO 242 238 238 PRO PRO A . n 
B 2 243 SER 243 239 239 SER SER A . n 
B 2 244 PHE 244 240 240 PHE PHE A . n 
B 2 245 PRO 245 241 241 PRO PRO A . n 
B 2 246 LYS 246 242 242 LYS LYS A . n 
B 2 247 TRP 247 243 243 TRP TRP A . n 
B 2 248 ALA 248 244 244 ALA ALA A . n 
B 2 249 ARG 249 245 245 ARG ARG A . n 
B 2 250 GLN 250 246 246 GLN GLN A . n 
B 2 251 ASP 251 247 247 ASP ASP A . n 
B 2 252 PHE 252 248 248 PHE PHE A . n 
B 2 253 SER 253 249 249 SER SER A . n 
B 2 254 LYS 254 250 250 LYS LYS A . n 
B 2 255 VAL 255 251 251 VAL VAL A . n 
B 2 256 VAL 256 252 252 VAL VAL A . n 
B 2 257 PRO 257 253 253 PRO PRO A . n 
B 2 258 PRO 258 254 254 PRO PRO A . n 
B 2 259 LEU 259 255 255 LEU LEU A . n 
B 2 260 ASP 260 256 256 ASP ASP A . n 
B 2 261 GLU 261 257 257 GLU GLU A . n 
B 2 262 ASP 262 258 258 ASP ASP A . n 
B 2 263 GLY 263 259 259 GLY GLY A . n 
B 2 264 ARG 264 260 260 ARG ARG A . n 
B 2 265 SER 265 261 261 SER SER A . n 
B 2 266 LEU 266 262 262 LEU LEU A . n 
B 2 267 LEU 267 263 263 LEU LEU A . n 
B 2 268 SER 268 264 264 SER SER A . n 
B 2 269 GLN 269 265 265 GLN GLN A . n 
B 2 270 MET 270 266 266 MET MET A . n 
B 2 271 LEU 271 267 267 LEU LEU A . n 
B 2 272 HIS 272 268 268 HIS HIS A . n 
B 2 273 TYR 273 269 269 TYR TYR A . n 
B 2 274 ASP 274 270 270 ASP ASP A . n 
B 2 275 PRO 275 271 271 PRO PRO A . n 
B 2 276 ASN 276 272 272 ASN ASN A . n 
B 2 277 LYS 277 273 273 LYS LYS A . n 
B 2 278 ARG 278 274 274 ARG ARG A . n 
B 2 279 ILE 279 275 275 ILE ILE A . n 
B 2 280 SER 280 276 276 SER SER A . n 
B 2 281 ALA 281 277 277 ALA ALA A . n 
B 2 282 LYS 282 278 278 LYS LYS A . n 
B 2 283 ALA 283 279 279 ALA ALA A . n 
B 2 284 ALA 284 280 280 ALA ALA A . n 
B 2 285 LEU 285 281 281 LEU LEU A . n 
B 2 286 ALA 286 282 282 ALA ALA A . n 
B 2 287 HIS 287 283 283 HIS HIS A . n 
B 2 288 PRO 288 284 284 PRO PRO A . n 
B 2 289 PHE 289 285 285 PHE PHE A . n 
B 2 290 PHE 290 286 286 PHE PHE A . n 
B 2 291 GLN 291 287 287 GLN GLN A . n 
B 2 292 ASP 292 288 288 ASP ASP A . n 
B 2 293 VAL 293 289 289 VAL VAL A . n 
B 2 294 THR 294 290 290 THR THR A . n 
B 2 295 LYS 295 291 291 LYS LYS A . n 
B 2 296 PRO 296 292 292 PRO PRO A . n 
B 2 297 VAL 297 293 293 VAL VAL A . n 
B 2 298 PRO 298 294 294 PRO PRO A . n 
B 2 299 HIS 299 295 295 HIS HIS A . n 
B 2 300 LEU 300 296 296 LEU LEU A . n 
B 2 301 ARG 301 297 297 ARG ARG A . n 
B 2 302 LEU 302 298 298 LEU LEU A . n 
C 1 1   GLY 1   171 171 GLY GLY B . n 
C 1 2   VAL 2   172 172 VAL VAL B . n 
C 1 3   ASN 3   173 173 ASN ASN B . n 
C 1 4   GLU 4   174 174 GLU GLU B . n 
C 1 5   VAL 5   175 175 VAL VAL B . n 
C 1 6   PRO 6   176 176 PRO PRO B . n 
C 1 7   ASP 7   177 177 ASP ASP B . n 
C 1 8   TYR 8   178 178 TYR TYR B . n 
C 1 9   HIS 9   179 179 HIS HIS B . n 
C 1 10  GLU 10  180 180 GLU GLU B . n 
C 1 11  ASP 11  181 181 ASP ASP B . n 
C 1 12  ILE 12  182 182 ILE ILE B . n 
C 1 13  HIS 13  183 183 HIS HIS B . n 
C 1 14  THR 14  184 184 THR THR B . n 
C 1 15  TYR 15  185 185 TYR TYR B . n 
C 1 16  LEU 16  186 186 LEU LEU B . n 
C 1 17  ARG 17  187 187 ARG ARG B . n 
C 1 18  GLU 18  188 188 GLU GLU B . n 
C 1 19  MET 19  189 189 MET MET B . n 
C 1 20  GLU 20  190 190 GLU GLU B . n 
C 1 21  VAL 21  191 191 VAL VAL B . n 
C 1 22  LYS 22  192 192 LYS LYS B . n 
C 1 23  CYS 23  193 193 CYS CYS B . n 
C 1 24  LYS 24  194 194 LYS LYS B . n 
C 1 25  PRO 25  195 195 PRO PRO B . n 
C 1 26  LYS 26  196 196 LYS LYS B . n 
C 1 27  VAL 27  197 197 VAL VAL B . n 
C 1 28  GLY 28  198 198 GLY GLY B . n 
C 1 29  TYR 29  199 199 TYR TYR B . n 
C 1 30  MET 30  200 200 MET MET B . n 
C 1 31  LYS 31  201 201 LYS LYS B . n 
C 1 32  LYS 32  202 202 LYS LYS B . n 
C 1 33  GLN 33  203 203 GLN GLN B . n 
C 1 34  PRO 34  204 204 PRO PRO B . n 
C 1 35  ASP 35  205 205 ASP ASP B . n 
C 1 36  ILE 36  206 206 ILE ILE B . n 
C 1 37  THR 37  207 207 THR THR B . n 
C 1 38  ASN 38  208 208 ASN ASN B . n 
C 1 39  SER 39  209 209 SER SER B . n 
C 1 40  MET 40  210 210 MET MET B . n 
C 1 41  ARG 41  211 211 ARG ARG B . n 
C 1 42  ALA 42  212 212 ALA ALA B . n 
C 1 43  ILE 43  213 213 ILE ILE B . n 
C 1 44  LEU 44  214 214 LEU LEU B . n 
C 1 45  VAL 45  215 215 VAL VAL B . n 
C 1 46  ASP 46  216 216 ASP ASP B . n 
C 1 47  TRP 47  217 217 TRP TRP B . n 
C 1 48  LEU 48  218 218 LEU LEU B . n 
C 1 49  VAL 49  219 219 VAL VAL B . n 
C 1 50  GLU 50  220 220 GLU GLU B . n 
C 1 51  VAL 51  221 221 VAL VAL B . n 
C 1 52  GLY 52  222 222 GLY GLY B . n 
C 1 53  GLU 53  223 223 GLU GLU B . n 
C 1 54  GLU 54  224 224 GLU GLU B . n 
C 1 55  TYR 55  225 225 TYR TYR B . n 
C 1 56  LYS 56  226 226 LYS LYS B . n 
C 1 57  LEU 57  227 227 LEU LEU B . n 
C 1 58  GLN 58  228 228 GLN GLN B . n 
C 1 59  ASN 59  229 229 ASN ASN B . n 
C 1 60  GLU 60  230 230 GLU GLU B . n 
C 1 61  THR 61  231 231 THR THR B . n 
C 1 62  LEU 62  232 232 LEU LEU B . n 
C 1 63  HIS 63  233 233 HIS HIS B . n 
C 1 64  LEU 64  234 234 LEU LEU B . n 
C 1 65  ALA 65  235 235 ALA ALA B . n 
C 1 66  VAL 66  236 236 VAL VAL B . n 
C 1 67  ASN 67  237 237 ASN ASN B . n 
C 1 68  TYR 68  238 238 TYR TYR B . n 
C 1 69  ILE 69  239 239 ILE ILE B . n 
C 1 70  ASP 70  240 240 ASP ASP B . n 
C 1 71  ARG 71  241 241 ARG ARG B . n 
C 1 72  PHE 72  242 242 PHE PHE B . n 
C 1 73  LEU 73  243 243 LEU LEU B . n 
C 1 74  SER 74  244 244 SER SER B . n 
C 1 75  SER 75  245 245 SER SER B . n 
C 1 76  MET 76  246 246 MET MET B . n 
C 1 77  SER 77  247 247 SER SER B . n 
C 1 78  VAL 78  248 248 VAL VAL B . n 
C 1 79  LEU 79  249 249 LEU LEU B . n 
C 1 80  ARG 80  250 250 ARG ARG B . n 
C 1 81  GLY 81  251 251 GLY GLY B . n 
C 1 82  LYS 82  252 252 LYS LYS B . n 
C 1 83  LEU 83  253 253 LEU LEU B . n 
C 1 84  GLN 84  254 254 GLN GLN B . n 
C 1 85  LEU 85  255 255 LEU LEU B . n 
C 1 86  VAL 86  256 256 VAL VAL B . n 
C 1 87  GLY 87  257 257 GLY GLY B . n 
C 1 88  THR 88  258 258 THR THR B . n 
C 1 89  ALA 89  259 259 ALA ALA B . n 
C 1 90  ALA 90  260 260 ALA ALA B . n 
C 1 91  MET 91  261 261 MET MET B . n 
C 1 92  LEU 92  262 262 LEU LEU B . n 
C 1 93  LEU 93  263 263 LEU LEU B . n 
C 1 94  ALA 94  264 264 ALA ALA B . n 
C 1 95  SER 95  265 265 SER SER B . n 
C 1 96  LYS 96  266 266 LYS LYS B . n 
C 1 97  PHE 97  267 267 PHE PHE B . n 
C 1 98  GLU 98  268 268 GLU GLU B . n 
C 1 99  GLU 99  269 269 GLU GLU B . n 
C 1 100 ILE 100 270 270 ILE ILE B . n 
C 1 101 TYR 101 271 271 TYR TYR B . n 
C 1 102 PRO 102 272 272 PRO PRO B . n 
C 1 103 PRO 103 273 273 PRO PRO B . n 
C 1 104 GLU 104 274 274 GLU GLU B . n 
C 1 105 VAL 105 275 275 VAL VAL B . n 
C 1 106 ALA 106 276 276 ALA ALA B . n 
C 1 107 GLU 107 277 277 GLU GLU B . n 
C 1 108 PHE 108 278 278 PHE PHE B . n 
C 1 109 VAL 109 279 279 VAL VAL B . n 
C 1 110 TYR 110 280 280 TYR TYR B . n 
C 1 111 ILE 111 281 281 ILE ILE B . n 
C 1 112 THR 112 282 282 THR THR B . n 
C 1 113 ASP 113 283 283 ASP ASP B . n 
C 1 114 ASP 114 284 284 ASP ASP B . n 
C 1 115 THR 115 285 285 THR THR B . n 
C 1 116 TYR 116 286 286 TYR TYR B . n 
C 1 117 THR 117 287 287 THR THR B . n 
C 1 118 LYS 118 288 288 LYS LYS B . n 
C 1 119 LYS 119 289 289 LYS LYS B . n 
C 1 120 GLN 120 290 290 GLN GLN B . n 
C 1 121 VAL 121 291 291 VAL VAL B . n 
C 1 122 LEU 122 292 292 LEU LEU B . n 
C 1 123 ARG 123 293 293 ARG ARG B . n 
C 1 124 MET 124 294 294 MET MET B . n 
C 1 125 GLU 125 295 295 GLU GLU B . n 
C 1 126 HIS 126 296 296 HIS HIS B . n 
C 1 127 LEU 127 297 297 LEU LEU B . n 
C 1 128 VAL 128 298 298 VAL VAL B . n 
C 1 129 LEU 129 299 299 LEU LEU B . n 
C 1 130 LYS 130 300 300 LYS LYS B . n 
C 1 131 VAL 131 301 301 VAL VAL B . n 
C 1 132 LEU 132 302 302 LEU LEU B . n 
C 1 133 ALA 133 303 303 ALA ALA B . n 
C 1 134 PHE 134 304 304 PHE PHE B . n 
C 1 135 ASP 135 305 305 ASP ASP B . n 
C 1 136 LEU 136 306 306 LEU LEU B . n 
C 1 137 ALA 137 307 307 ALA ALA B . n 
C 1 138 ALA 138 308 308 ALA ALA B . n 
C 1 139 PRO 139 309 309 PRO PRO B . n 
C 1 140 THR 140 310 310 THR THR B . n 
C 1 141 ILE 141 311 311 ILE ILE B . n 
C 1 142 ASN 142 312 312 ASN ASN B . n 
C 1 143 GLN 143 313 313 GLN GLN B . n 
C 1 144 PHE 144 314 314 PHE PHE B . n 
C 1 145 LEU 145 315 315 LEU LEU B . n 
C 1 146 THR 146 316 316 THR THR B . n 
C 1 147 GLN 147 317 317 GLN GLN B . n 
C 1 148 TYR 148 318 318 TYR TYR B . n 
C 1 149 PHE 149 319 319 PHE PHE B . n 
C 1 150 LEU 150 320 320 LEU LEU B . n 
C 1 151 HIS 151 321 321 HIS HIS B . n 
C 1 152 GLN 152 322 322 GLN GLN B . n 
C 1 153 GLN 153 323 323 GLN GLN B . n 
C 1 154 PRO 154 324 324 PRO PRO B . n 
C 1 155 ALA 155 325 325 ALA ALA B . n 
C 1 156 ASN 156 326 326 ASN ASN B . n 
C 1 157 CYS 157 327 327 CYS CYS B . n 
C 1 158 LYS 158 328 328 LYS LYS B . n 
C 1 159 VAL 159 329 329 VAL VAL B . n 
C 1 160 GLU 160 330 330 GLU GLU B . n 
C 1 161 SER 161 331 331 SER SER B . n 
C 1 162 LEU 162 332 332 LEU LEU B . n 
C 1 163 ALA 163 333 333 ALA ALA B . n 
C 1 164 MET 164 334 334 MET MET B . n 
C 1 165 PHE 165 335 335 PHE PHE B . n 
C 1 166 LEU 166 336 336 LEU LEU B . n 
C 1 167 GLY 167 337 337 GLY GLY B . n 
C 1 168 GLU 168 338 338 GLU GLU B . n 
C 1 169 LEU 169 339 339 LEU LEU B . n 
C 1 170 SER 170 340 340 SER SER B . n 
C 1 171 LEU 171 341 341 LEU LEU B . n 
C 1 172 ILE 172 342 342 ILE ILE B . n 
C 1 173 ASP 173 343 343 ASP ASP B . n 
C 1 174 ALA 174 344 344 ALA ALA B . n 
C 1 175 ASP 175 345 345 ASP ASP B . n 
C 1 176 PRO 176 346 346 PRO PRO B . n 
C 1 177 TYR 177 347 347 TYR TYR B . n 
C 1 178 LEU 178 348 348 LEU LEU B . n 
C 1 179 LYS 179 349 349 LYS LYS B . n 
C 1 180 TYR 180 350 350 TYR TYR B . n 
C 1 181 LEU 181 351 351 LEU LEU B . n 
C 1 182 PRO 182 352 352 PRO PRO B . n 
C 1 183 SER 183 353 353 SER SER B . n 
C 1 184 VAL 184 354 354 VAL VAL B . n 
C 1 185 ILE 185 355 355 ILE ILE B . n 
C 1 186 ALA 186 356 356 ALA ALA B . n 
C 1 187 ALA 187 357 357 ALA ALA B . n 
C 1 188 ALA 188 358 358 ALA ALA B . n 
C 1 189 ALA 189 359 359 ALA ALA B . n 
C 1 190 PHE 190 360 360 PHE PHE B . n 
C 1 191 HIS 191 361 361 HIS HIS B . n 
C 1 192 LEU 192 362 362 LEU LEU B . n 
C 1 193 ALA 193 363 363 ALA ALA B . n 
C 1 194 LEU 194 364 364 LEU LEU B . n 
C 1 195 TYR 195 365 365 TYR TYR B . n 
C 1 196 THR 196 366 366 THR THR B . n 
C 1 197 VAL 197 367 367 VAL VAL B . n 
C 1 198 THR 198 368 368 THR THR B . n 
C 1 199 GLY 199 369 369 GLY GLY B . n 
C 1 200 GLN 200 370 370 GLN GLN B . n 
C 1 201 SER 201 371 371 SER SER B . n 
C 1 202 TRP 202 372 372 TRP TRP B . n 
C 1 203 PRO 203 373 373 PRO PRO B . n 
C 1 204 GLU 204 374 374 GLU GLU B . n 
C 1 205 SER 205 375 375 SER SER B . n 
C 1 206 LEU 206 376 376 LEU LEU B . n 
C 1 207 VAL 207 377 377 VAL VAL B . n 
C 1 208 GLN 208 378 378 GLN GLN B . n 
C 1 209 LYS 209 379 379 LYS LYS B . n 
C 1 210 THR 210 380 380 THR THR B . n 
C 1 211 GLY 211 381 381 GLY GLY B . n 
C 1 212 TYR 212 382 382 TYR TYR B . n 
C 1 213 THR 213 383 383 THR THR B . n 
C 1 214 LEU 214 384 384 LEU LEU B . n 
C 1 215 GLU 215 385 385 GLU GLU B . n 
C 1 216 THR 216 386 386 THR THR B . n 
C 1 217 LEU 217 387 387 LEU LEU B . n 
C 1 218 LYS 218 388 388 LYS LYS B . n 
C 1 219 PRO 219 389 389 PRO PRO B . n 
C 1 220 CYS 220 390 390 CYS CYS B . n 
C 1 221 LEU 221 391 391 LEU LEU B . n 
C 1 222 LEU 222 392 392 LEU LEU B . n 
C 1 223 ASP 223 393 393 ASP ASP B . n 
C 1 224 LEU 224 394 394 LEU LEU B . n 
C 1 225 HIS 225 395 395 HIS HIS B . n 
C 1 226 GLN 226 396 396 GLN GLN B . n 
C 1 227 THR 227 397 397 THR THR B . n 
C 1 228 TYR 228 398 398 TYR TYR B . n 
C 1 229 LEU 229 399 399 LEU LEU B . n 
C 1 230 ARG 230 400 400 ARG ARG B . n 
C 1 231 ALA 231 401 401 ALA ALA B . n 
C 1 232 PRO 232 402 402 PRO PRO B . n 
C 1 233 GLN 233 403 403 GLN GLN B . n 
C 1 234 HIS 234 404 404 HIS HIS B . n 
C 1 235 ALA 235 405 405 ALA ALA B . n 
C 1 236 GLN 236 406 406 GLN GLN B . n 
C 1 237 GLN 237 407 407 GLN GLN B . n 
C 1 238 SER 238 408 408 SER SER B . n 
C 1 239 ILE 239 409 409 ILE ILE B . n 
C 1 240 ARG 240 410 410 ARG ARG B . n 
C 1 241 GLU 241 411 411 GLU GLU B . n 
C 1 242 LYS 242 412 412 LYS LYS B . n 
C 1 243 TYR 243 413 413 TYR TYR B . n 
C 1 244 LYS 244 414 414 LYS LYS B . n 
C 1 245 ASN 245 415 415 ASN ASN B . n 
C 1 246 SER 246 416 416 SER SER B . n 
C 1 247 LYS 247 417 417 LYS LYS B . n 
C 1 248 TYR 248 418 418 TYR TYR B . n 
C 1 249 HIS 249 419 419 HIS HIS B . n 
C 1 250 GLY 250 420 420 GLY GLY B . n 
C 1 251 VAL 251 421 421 VAL VAL B . n 
C 1 252 SER 252 422 422 SER SER B . n 
C 1 253 LEU 253 423 423 LEU LEU B . n 
C 1 254 LEU 254 424 424 LEU LEU B . n 
C 1 255 ASN 255 425 425 ASN ASN B . n 
C 1 256 PRO 256 426 426 PRO PRO B . n 
C 1 257 PRO 257 427 427 PRO PRO B . n 
C 1 258 GLU 258 428 428 GLU GLU B . n 
C 1 259 THR 259 429 429 THR THR B . n 
C 1 260 LEU 260 430 430 LEU LEU B . n 
C 1 261 ASN 261 431 431 ASN ASN B . n 
C 1 262 VAL 262 432 432 VAL VAL B . n 
C 1 263 HIS 263 433 ?   ?   ?   B . n 
C 1 264 HIS 264 434 ?   ?   ?   B . n 
C 1 265 HIS 265 435 ?   ?   ?   B . n 
C 1 266 HIS 266 436 ?   ?   ?   B . n 
C 1 267 HIS 267 437 ?   ?   ?   B . n 
C 1 268 HIS 268 438 ?   ?   ?   B . n 
D 2 1   GLY 1   -3  ?   ?   ?   C . n 
D 2 2   PRO 2   -2  ?   ?   ?   C . n 
D 2 3   GLY 3   -1  ?   ?   ?   C . n 
D 2 4   SER 4   0   0   SER SER C . n 
D 2 5   MET 5   1   1   MET MET C . n 
D 2 6   GLU 6   2   2   GLU GLU C . n 
D 2 7   ASN 7   3   3   ASN ASN C . n 
D 2 8   PHE 8   4   4   PHE PHE C . n 
D 2 9   GLN 9   5   5   GLN GLN C . n 
D 2 10  LYS 10  6   6   LYS LYS C . n 
D 2 11  VAL 11  7   7   VAL VAL C . n 
D 2 12  GLU 12  8   8   GLU GLU C . n 
D 2 13  LYS 13  9   9   LYS LYS C . n 
D 2 14  ILE 14  10  10  ILE ILE C . n 
D 2 15  GLY 15  11  11  GLY GLY C . n 
D 2 16  GLU 16  12  12  GLU GLU C . n 
D 2 17  GLY 17  13  13  GLY GLY C . n 
D 2 18  THR 18  14  14  THR THR C . n 
D 2 19  TYR 19  15  15  TYR TYR C . n 
D 2 20  GLY 20  16  16  GLY GLY C . n 
D 2 21  VAL 21  17  17  VAL VAL C . n 
D 2 22  VAL 22  18  18  VAL VAL C . n 
D 2 23  TYR 23  19  19  TYR TYR C . n 
D 2 24  LYS 24  20  20  LYS LYS C . n 
D 2 25  ALA 25  21  21  ALA ALA C . n 
D 2 26  ARG 26  22  22  ARG ARG C . n 
D 2 27  ASN 27  23  23  ASN ASN C . n 
D 2 28  LYS 28  24  24  LYS LYS C . n 
D 2 29  LEU 29  25  25  LEU LEU C . n 
D 2 30  THR 30  26  26  THR THR C . n 
D 2 31  GLY 31  27  27  GLY GLY C . n 
D 2 32  GLU 32  28  28  GLU GLU C . n 
D 2 33  VAL 33  29  29  VAL VAL C . n 
D 2 34  VAL 34  30  30  VAL VAL C . n 
D 2 35  ALA 35  31  31  ALA ALA C . n 
D 2 36  LEU 36  32  32  LEU LEU C . n 
D 2 37  LYS 37  33  33  LYS LYS C . n 
D 2 38  LYS 38  34  34  LYS LYS C . n 
D 2 39  ILE 39  35  35  ILE ILE C . n 
D 2 40  ARG 40  36  36  ARG ARG C . n 
D 2 41  LEU 41  37  37  LEU LEU C . n 
D 2 42  ASP 42  38  38  ASP ASP C . n 
D 2 43  THR 43  39  39  THR THR C . n 
D 2 44  GLU 44  40  40  GLU GLU C . n 
D 2 45  THR 45  41  41  THR THR C . n 
D 2 46  GLU 46  42  42  GLU GLU C . n 
D 2 47  GLY 47  43  43  GLY GLY C . n 
D 2 48  VAL 48  44  44  VAL VAL C . n 
D 2 49  PRO 49  45  45  PRO PRO C . n 
D 2 50  SER 50  46  46  SER SER C . n 
D 2 51  THR 51  47  47  THR THR C . n 
D 2 52  ALA 52  48  48  ALA ALA C . n 
D 2 53  ILE 53  49  49  ILE ILE C . n 
D 2 54  ARG 54  50  50  ARG ARG C . n 
D 2 55  GLU 55  51  51  GLU GLU C . n 
D 2 56  ILE 56  52  52  ILE ILE C . n 
D 2 57  SER 57  53  53  SER SER C . n 
D 2 58  LEU 58  54  54  LEU LEU C . n 
D 2 59  LEU 59  55  55  LEU LEU C . n 
D 2 60  LYS 60  56  56  LYS LYS C . n 
D 2 61  GLU 61  57  57  GLU GLU C . n 
D 2 62  LEU 62  58  58  LEU LEU C . n 
D 2 63  ASN 63  59  59  ASN ASN C . n 
D 2 64  HIS 64  60  60  HIS HIS C . n 
D 2 65  PRO 65  61  61  PRO PRO C . n 
D 2 66  ASN 66  62  62  ASN ASN C . n 
D 2 67  ILE 67  63  63  ILE ILE C . n 
D 2 68  VAL 68  64  64  VAL VAL C . n 
D 2 69  LYS 69  65  65  LYS LYS C . n 
D 2 70  LEU 70  66  66  LEU LEU C . n 
D 2 71  LEU 71  67  67  LEU LEU C . n 
D 2 72  ASP 72  68  68  ASP ASP C . n 
D 2 73  VAL 73  69  69  VAL VAL C . n 
D 2 74  ILE 74  70  70  ILE ILE C . n 
D 2 75  HIS 75  71  71  HIS HIS C . n 
D 2 76  THR 76  72  72  THR THR C . n 
D 2 77  GLU 77  73  73  GLU GLU C . n 
D 2 78  ASN 78  74  74  ASN ASN C . n 
D 2 79  LYS 79  75  75  LYS LYS C . n 
D 2 80  LEU 80  76  76  LEU LEU C . n 
D 2 81  TYR 81  77  77  TYR TYR C . n 
D 2 82  LEU 82  78  78  LEU LEU C . n 
D 2 83  VAL 83  79  79  VAL VAL C . n 
D 2 84  PHE 84  80  80  PHE PHE C . n 
D 2 85  GLU 85  81  81  GLU GLU C . n 
D 2 86  PHE 86  82  82  PHE PHE C . n 
D 2 87  LEU 87  83  83  LEU LEU C . n 
D 2 88  HIS 88  84  84  HIS HIS C . n 
D 2 89  GLN 89  85  85  GLN GLN C . n 
D 2 90  ASP 90  86  86  ASP ASP C . n 
D 2 91  LEU 91  87  87  LEU LEU C . n 
D 2 92  LYS 92  88  88  LYS LYS C . n 
D 2 93  LYS 93  89  89  LYS LYS C . n 
D 2 94  PHE 94  90  90  PHE PHE C . n 
D 2 95  MET 95  91  91  MET MET C . n 
D 2 96  ASP 96  92  92  ASP ASP C . n 
D 2 97  ALA 97  93  93  ALA ALA C . n 
D 2 98  SER 98  94  94  SER SER C . n 
D 2 99  ALA 99  95  95  ALA ALA C . n 
D 2 100 LEU 100 96  96  LEU LEU C . n 
D 2 101 THR 101 97  97  THR THR C . n 
D 2 102 GLY 102 98  98  GLY GLY C . n 
D 2 103 ILE 103 99  99  ILE ILE C . n 
D 2 104 PRO 104 100 100 PRO PRO C . n 
D 2 105 LEU 105 101 101 LEU LEU C . n 
D 2 106 PRO 106 102 102 PRO PRO C . n 
D 2 107 LEU 107 103 103 LEU LEU C . n 
D 2 108 ILE 108 104 104 ILE ILE C . n 
D 2 109 LYS 109 105 105 LYS LYS C . n 
D 2 110 SER 110 106 106 SER SER C . n 
D 2 111 TYR 111 107 107 TYR TYR C . n 
D 2 112 LEU 112 108 108 LEU LEU C . n 
D 2 113 PHE 113 109 109 PHE PHE C . n 
D 2 114 GLN 114 110 110 GLN GLN C . n 
D 2 115 LEU 115 111 111 LEU LEU C . n 
D 2 116 LEU 116 112 112 LEU LEU C . n 
D 2 117 GLN 117 113 113 GLN GLN C . n 
D 2 118 GLY 118 114 114 GLY GLY C . n 
D 2 119 LEU 119 115 115 LEU LEU C . n 
D 2 120 ALA 120 116 116 ALA ALA C . n 
D 2 121 PHE 121 117 117 PHE PHE C . n 
D 2 122 CYS 122 118 118 CYS CYS C . n 
D 2 123 HIS 123 119 119 HIS HIS C . n 
D 2 124 SER 124 120 120 SER SER C . n 
D 2 125 HIS 125 121 121 HIS HIS C . n 
D 2 126 ARG 126 122 122 ARG ARG C . n 
D 2 127 VAL 127 123 123 VAL VAL C . n 
D 2 128 LEU 128 124 124 LEU LEU C . n 
D 2 129 HIS 129 125 125 HIS HIS C . n 
D 2 130 ARG 130 126 126 ARG ARG C . n 
D 2 131 ASP 131 127 127 ASP ASP C . n 
D 2 132 LEU 132 128 128 LEU LEU C . n 
D 2 133 LYS 133 129 129 LYS LYS C . n 
D 2 134 PRO 134 130 130 PRO PRO C . n 
D 2 135 GLN 135 131 131 GLN GLN C . n 
D 2 136 ASN 136 132 132 ASN ASN C . n 
D 2 137 LEU 137 133 133 LEU LEU C . n 
D 2 138 LEU 138 134 134 LEU LEU C . n 
D 2 139 ILE 139 135 135 ILE ILE C . n 
D 2 140 ASN 140 136 136 ASN ASN C . n 
D 2 141 THR 141 137 137 THR THR C . n 
D 2 142 GLU 142 138 138 GLU GLU C . n 
D 2 143 GLY 143 139 139 GLY GLY C . n 
D 2 144 ALA 144 140 140 ALA ALA C . n 
D 2 145 ILE 145 141 141 ILE ILE C . n 
D 2 146 LYS 146 142 142 LYS LYS C . n 
D 2 147 LEU 147 143 143 LEU LEU C . n 
D 2 148 ALA 148 144 144 ALA ALA C . n 
D 2 149 ASP 149 145 145 ASP ASP C . n 
D 2 150 PHE 150 146 146 PHE PHE C . n 
D 2 151 GLY 151 147 147 GLY GLY C . n 
D 2 152 LEU 152 148 148 LEU LEU C . n 
D 2 153 ALA 153 149 149 ALA ALA C . n 
D 2 154 ARG 154 150 150 ARG ARG C . n 
D 2 155 ALA 155 151 151 ALA ALA C . n 
D 2 156 PHE 156 152 152 PHE PHE C . n 
D 2 157 GLY 157 153 153 GLY GLY C . n 
D 2 158 VAL 158 154 154 VAL VAL C . n 
D 2 159 PRO 159 155 155 PRO PRO C . n 
D 2 160 VAL 160 156 156 VAL VAL C . n 
D 2 161 ARG 161 157 157 ARG ARG C . n 
D 2 162 THR 162 158 158 THR THR C . n 
D 2 163 TYR 163 159 159 TYR TYR C . n 
D 2 164 TPO 164 160 160 TPO TPO C . n 
D 2 165 HIS 165 161 161 HIS HIS C . n 
D 2 166 GLU 166 162 162 GLU GLU C . n 
D 2 167 VAL 167 163 163 VAL VAL C . n 
D 2 168 VAL 168 164 164 VAL VAL C . n 
D 2 169 THR 169 165 165 THR THR C . n 
D 2 170 LEU 170 166 166 LEU LEU C . n 
D 2 171 TRP 171 167 167 TRP TRP C . n 
D 2 172 TYR 172 168 168 TYR TYR C . n 
D 2 173 ARG 173 169 169 ARG ARG C . n 
D 2 174 ALA 174 170 170 ALA ALA C . n 
D 2 175 PRO 175 171 171 PRO PRO C . n 
D 2 176 GLU 176 172 172 GLU GLU C . n 
D 2 177 ILE 177 173 173 ILE ILE C . n 
D 2 178 LEU 178 174 174 LEU LEU C . n 
D 2 179 LEU 179 175 175 LEU LEU C . n 
D 2 180 GLY 180 176 176 GLY GLY C . n 
D 2 181 CYS 181 177 177 CYS CYS C . n 
D 2 182 LYS 182 178 178 LYS LYS C . n 
D 2 183 TYR 183 179 179 TYR TYR C . n 
D 2 184 TYR 184 180 180 TYR TYR C . n 
D 2 185 SER 185 181 181 SER SER C . n 
D 2 186 THR 186 182 182 THR THR C . n 
D 2 187 ALA 187 183 183 ALA ALA C . n 
D 2 188 VAL 188 184 184 VAL VAL C . n 
D 2 189 ASP 189 185 185 ASP ASP C . n 
D 2 190 ILE 190 186 186 ILE ILE C . n 
D 2 191 TRP 191 187 187 TRP TRP C . n 
D 2 192 SER 192 188 188 SER SER C . n 
D 2 193 LEU 193 189 189 LEU LEU C . n 
D 2 194 GLY 194 190 190 GLY GLY C . n 
D 2 195 CYS 195 191 191 CYS CYS C . n 
D 2 196 ILE 196 192 192 ILE ILE C . n 
D 2 197 PHE 197 193 193 PHE PHE C . n 
D 2 198 ALA 198 194 194 ALA ALA C . n 
D 2 199 GLU 199 195 195 GLU GLU C . n 
D 2 200 MET 200 196 196 MET MET C . n 
D 2 201 VAL 201 197 197 VAL VAL C . n 
D 2 202 THR 202 198 198 THR THR C . n 
D 2 203 ARG 203 199 199 ARG ARG C . n 
D 2 204 ARG 204 200 200 ARG ARG C . n 
D 2 205 ALA 205 201 201 ALA ALA C . n 
D 2 206 LEU 206 202 202 LEU LEU C . n 
D 2 207 PHE 207 203 203 PHE PHE C . n 
D 2 208 PRO 208 204 204 PRO PRO C . n 
D 2 209 GLY 209 205 205 GLY GLY C . n 
D 2 210 ASP 210 206 206 ASP ASP C . n 
D 2 211 SER 211 207 207 SER SER C . n 
D 2 212 GLU 212 208 208 GLU GLU C . n 
D 2 213 ILE 213 209 209 ILE ILE C . n 
D 2 214 ASP 214 210 210 ASP ASP C . n 
D 2 215 GLN 215 211 211 GLN GLN C . n 
D 2 216 LEU 216 212 212 LEU LEU C . n 
D 2 217 PHE 217 213 213 PHE PHE C . n 
D 2 218 ARG 218 214 214 ARG ARG C . n 
D 2 219 ILE 219 215 215 ILE ILE C . n 
D 2 220 PHE 220 216 216 PHE PHE C . n 
D 2 221 ARG 221 217 217 ARG ARG C . n 
D 2 222 THR 222 218 218 THR THR C . n 
D 2 223 LEU 223 219 219 LEU LEU C . n 
D 2 224 GLY 224 220 220 GLY GLY C . n 
D 2 225 THR 225 221 221 THR THR C . n 
D 2 226 PRO 226 222 222 PRO PRO C . n 
D 2 227 ASP 227 223 223 ASP ASP C . n 
D 2 228 GLU 228 224 224 GLU GLU C . n 
D 2 229 VAL 229 225 225 VAL VAL C . n 
D 2 230 VAL 230 226 226 VAL VAL C . n 
D 2 231 TRP 231 227 227 TRP TRP C . n 
D 2 232 PRO 232 228 228 PRO PRO C . n 
D 2 233 GLY 233 229 229 GLY GLY C . n 
D 2 234 VAL 234 230 230 VAL VAL C . n 
D 2 235 THR 235 231 231 THR THR C . n 
D 2 236 SER 236 232 232 SER SER C . n 
D 2 237 MET 237 233 233 MET MET C . n 
D 2 238 PRO 238 234 234 PRO PRO C . n 
D 2 239 ASP 239 235 235 ASP ASP C . n 
D 2 240 TYR 240 236 236 TYR TYR C . n 
D 2 241 LYS 241 237 237 LYS LYS C . n 
D 2 242 PRO 242 238 238 PRO PRO C . n 
D 2 243 SER 243 239 239 SER SER C . n 
D 2 244 PHE 244 240 240 PHE PHE C . n 
D 2 245 PRO 245 241 241 PRO PRO C . n 
D 2 246 LYS 246 242 242 LYS LYS C . n 
D 2 247 TRP 247 243 243 TRP TRP C . n 
D 2 248 ALA 248 244 244 ALA ALA C . n 
D 2 249 ARG 249 245 245 ARG ARG C . n 
D 2 250 GLN 250 246 246 GLN GLN C . n 
D 2 251 ASP 251 247 247 ASP ASP C . n 
D 2 252 PHE 252 248 248 PHE PHE C . n 
D 2 253 SER 253 249 249 SER SER C . n 
D 2 254 LYS 254 250 250 LYS LYS C . n 
D 2 255 VAL 255 251 251 VAL VAL C . n 
D 2 256 VAL 256 252 252 VAL VAL C . n 
D 2 257 PRO 257 253 253 PRO PRO C . n 
D 2 258 PRO 258 254 254 PRO PRO C . n 
D 2 259 LEU 259 255 255 LEU LEU C . n 
D 2 260 ASP 260 256 256 ASP ASP C . n 
D 2 261 GLU 261 257 257 GLU GLU C . n 
D 2 262 ASP 262 258 258 ASP ASP C . n 
D 2 263 GLY 263 259 259 GLY GLY C . n 
D 2 264 ARG 264 260 260 ARG ARG C . n 
D 2 265 SER 265 261 261 SER SER C . n 
D 2 266 LEU 266 262 262 LEU LEU C . n 
D 2 267 LEU 267 263 263 LEU LEU C . n 
D 2 268 SER 268 264 264 SER SER C . n 
D 2 269 GLN 269 265 265 GLN GLN C . n 
D 2 270 MET 270 266 266 MET MET C . n 
D 2 271 LEU 271 267 267 LEU LEU C . n 
D 2 272 HIS 272 268 268 HIS HIS C . n 
D 2 273 TYR 273 269 269 TYR TYR C . n 
D 2 274 ASP 274 270 270 ASP ASP C . n 
D 2 275 PRO 275 271 271 PRO PRO C . n 
D 2 276 ASN 276 272 272 ASN ASN C . n 
D 2 277 LYS 277 273 273 LYS LYS C . n 
D 2 278 ARG 278 274 274 ARG ARG C . n 
D 2 279 ILE 279 275 275 ILE ILE C . n 
D 2 280 SER 280 276 276 SER SER C . n 
D 2 281 ALA 281 277 277 ALA ALA C . n 
D 2 282 LYS 282 278 278 LYS LYS C . n 
D 2 283 ALA 283 279 279 ALA ALA C . n 
D 2 284 ALA 284 280 280 ALA ALA C . n 
D 2 285 LEU 285 281 281 LEU LEU C . n 
D 2 286 ALA 286 282 282 ALA ALA C . n 
D 2 287 HIS 287 283 283 HIS HIS C . n 
D 2 288 PRO 288 284 284 PRO PRO C . n 
D 2 289 PHE 289 285 285 PHE PHE C . n 
D 2 290 PHE 290 286 286 PHE PHE C . n 
D 2 291 GLN 291 287 287 GLN GLN C . n 
D 2 292 ASP 292 288 288 ASP ASP C . n 
D 2 293 VAL 293 289 289 VAL VAL C . n 
D 2 294 THR 294 290 290 THR THR C . n 
D 2 295 LYS 295 291 291 LYS LYS C . n 
D 2 296 PRO 296 292 292 PRO PRO C . n 
D 2 297 VAL 297 293 293 VAL VAL C . n 
D 2 298 PRO 298 294 294 PRO PRO C . n 
D 2 299 HIS 299 295 295 HIS HIS C . n 
D 2 300 LEU 300 296 296 LEU LEU C . n 
D 2 301 ARG 301 297 ?   ?   ?   C . n 
D 2 302 LEU 302 298 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        7ZX 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   7ZX 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 7ZX 1  601 601  7ZX DRG A . 
F 3 7ZX 1  301 474  7ZX DRG C . 
G 4 HOH 1  501 779  HOH HOH D . 
G 4 HOH 2  502 706  HOH HOH D . 
G 4 HOH 3  503 701  HOH HOH D . 
G 4 HOH 4  504 555  HOH HOH D . 
G 4 HOH 5  505 699  HOH HOH D . 
G 4 HOH 6  506 667  HOH HOH D . 
G 4 HOH 7  507 724  HOH HOH D . 
G 4 HOH 8  508 668  HOH HOH D . 
G 4 HOH 9  509 551  HOH HOH D . 
G 4 HOH 10 510 905  HOH HOH D . 
G 4 HOH 11 511 679  HOH HOH D . 
G 4 HOH 12 512 502  HOH HOH D . 
G 4 HOH 13 513 676  HOH HOH D . 
G 4 HOH 14 514 771  HOH HOH D . 
G 4 HOH 15 515 820  HOH HOH D . 
G 4 HOH 16 516 766  HOH HOH D . 
G 4 HOH 17 517 545  HOH HOH D . 
G 4 HOH 18 518 566  HOH HOH D . 
G 4 HOH 19 519 556  HOH HOH D . 
G 4 HOH 20 520 716  HOH HOH D . 
G 4 HOH 21 521 552  HOH HOH D . 
G 4 HOH 22 522 678  HOH HOH D . 
G 4 HOH 23 523 683  HOH HOH D . 
G 4 HOH 24 524 508  HOH HOH D . 
G 4 HOH 25 525 842  HOH HOH D . 
G 4 HOH 26 526 861  HOH HOH D . 
G 4 HOH 27 527 561  HOH HOH D . 
G 4 HOH 28 528 1242 HOH HOH D . 
G 4 HOH 29 529 572  HOH HOH D . 
G 4 HOH 30 530 482  HOH HOH D . 
H 4 HOH 1  701 529  HOH HOH A . 
H 4 HOH 2  702 723  HOH HOH A . 
H 4 HOH 3  703 670  HOH HOH A . 
H 4 HOH 4  704 577  HOH HOH A . 
H 4 HOH 5  705 825  HOH HOH A . 
H 4 HOH 6  706 511  HOH HOH A . 
H 4 HOH 7  707 598  HOH HOH A . 
H 4 HOH 8  708 586  HOH HOH A . 
H 4 HOH 9  709 478  HOH HOH A . 
H 4 HOH 10 710 579  HOH HOH A . 
H 4 HOH 11 711 791  HOH HOH A . 
H 4 HOH 12 712 594  HOH HOH A . 
H 4 HOH 13 713 582  HOH HOH A . 
H 4 HOH 14 714 545  HOH HOH A . 
H 4 HOH 15 715 530  HOH HOH A . 
H 4 HOH 16 716 516  HOH HOH A . 
H 4 HOH 17 717 580  HOH HOH A . 
H 4 HOH 18 718 566  HOH HOH A . 
H 4 HOH 19 719 527  HOH HOH A . 
H 4 HOH 20 720 748  HOH HOH A . 
H 4 HOH 21 721 512  HOH HOH A . 
H 4 HOH 22 722 534  HOH HOH A . 
H 4 HOH 23 723 535  HOH HOH A . 
H 4 HOH 24 724 538  HOH HOH A . 
H 4 HOH 25 725 424  HOH HOH A . 
H 4 HOH 26 726 588  HOH HOH A . 
H 4 HOH 27 727 853  HOH HOH A . 
H 4 HOH 28 728 520  HOH HOH A . 
H 4 HOH 29 729 589  HOH HOH A . 
H 4 HOH 30 730 686  HOH HOH A . 
H 4 HOH 31 731 515  HOH HOH A . 
H 4 HOH 32 732 468  HOH HOH A . 
H 4 HOH 33 733 522  HOH HOH A . 
H 4 HOH 34 734 425  HOH HOH A . 
H 4 HOH 35 735 528  HOH HOH A . 
H 4 HOH 36 736 514  HOH HOH A . 
H 4 HOH 37 737 521  HOH HOH A . 
H 4 HOH 38 738 574  HOH HOH A . 
H 4 HOH 39 739 585  HOH HOH A . 
H 4 HOH 40 740 517  HOH HOH A . 
H 4 HOH 41 741 531  HOH HOH A . 
H 4 HOH 42 742 532  HOH HOH A . 
H 4 HOH 43 743 584  HOH HOH A . 
H 4 HOH 44 744 518  HOH HOH A . 
H 4 HOH 45 745 744  HOH HOH A . 
H 4 HOH 46 746 629  HOH HOH A . 
H 4 HOH 47 747 581  HOH HOH A . 
H 4 HOH 48 748 600  HOH HOH A . 
H 4 HOH 49 749 595  HOH HOH A . 
H 4 HOH 50 750 788  HOH HOH A . 
H 4 HOH 51 751 536  HOH HOH A . 
H 4 HOH 52 752 1258 HOH HOH A . 
H 4 HOH 53 753 727  HOH HOH A . 
H 4 HOH 54 754 591  HOH HOH A . 
H 4 HOH 55 755 640  HOH HOH A . 
H 4 HOH 56 756 674  HOH HOH A . 
H 4 HOH 57 757 1108 HOH HOH A . 
H 4 HOH 58 758 599  HOH HOH A . 
H 4 HOH 59 759 487  HOH HOH A . 
H 4 HOH 60 760 526  HOH HOH A . 
H 4 HOH 61 761 597  HOH HOH A . 
H 4 HOH 62 762 697  HOH HOH A . 
H 4 HOH 63 763 532  HOH HOH A . 
H 4 HOH 64 764 524  HOH HOH A . 
H 4 HOH 65 765 757  HOH HOH A . 
H 4 HOH 66 766 593  HOH HOH A . 
H 4 HOH 67 767 462  HOH HOH A . 
H 4 HOH 68 768 590  HOH HOH A . 
H 4 HOH 69 769 513  HOH HOH A . 
H 4 HOH 70 770 484  HOH HOH A . 
H 4 HOH 71 771 465  HOH HOH A . 
H 4 HOH 72 772 525  HOH HOH A . 
H 4 HOH 73 773 579  HOH HOH A . 
H 4 HOH 74 774 537  HOH HOH A . 
I 4 HOH 1  501 648  HOH HOH B . 
I 4 HOH 2  502 633  HOH HOH B . 
I 4 HOH 3  503 637  HOH HOH B . 
I 4 HOH 4  504 608  HOH HOH B . 
I 4 HOH 5  505 807  HOH HOH B . 
I 4 HOH 6  506 630  HOH HOH B . 
I 4 HOH 7  507 627  HOH HOH B . 
I 4 HOH 8  508 677  HOH HOH B . 
I 4 HOH 9  509 612  HOH HOH B . 
I 4 HOH 10 510 621  HOH HOH B . 
I 4 HOH 11 511 619  HOH HOH B . 
I 4 HOH 12 512 611  HOH HOH B . 
I 4 HOH 13 513 736  HOH HOH B . 
I 4 HOH 14 514 685  HOH HOH B . 
I 4 HOH 15 515 573  HOH HOH B . 
I 4 HOH 16 516 523  HOH HOH B . 
I 4 HOH 17 517 512  HOH HOH B . 
I 4 HOH 18 518 576  HOH HOH B . 
I 4 HOH 19 519 606  HOH HOH B . 
I 4 HOH 20 520 774  HOH HOH B . 
I 4 HOH 21 521 615  HOH HOH B . 
I 4 HOH 22 522 572  HOH HOH B . 
I 4 HOH 23 523 751  HOH HOH B . 
I 4 HOH 24 524 635  HOH HOH B . 
I 4 HOH 25 525 1252 HOH HOH B . 
I 4 HOH 26 526 618  HOH HOH B . 
I 4 HOH 27 527 799  HOH HOH B . 
I 4 HOH 28 528 636  HOH HOH B . 
I 4 HOH 29 529 805  HOH HOH B . 
I 4 HOH 30 530 617  HOH HOH B . 
I 4 HOH 31 531 694  HOH HOH B . 
I 4 HOH 32 532 430  HOH HOH B . 
I 4 HOH 33 533 559  HOH HOH B . 
I 4 HOH 34 534 660  HOH HOH B . 
I 4 HOH 35 535 625  HOH HOH B . 
I 4 HOH 36 536 768  HOH HOH B . 
I 4 HOH 37 537 607  HOH HOH B . 
I 4 HOH 38 538 579  HOH HOH B . 
I 4 HOH 39 539 602  HOH HOH B . 
I 4 HOH 40 540 651  HOH HOH B . 
I 4 HOH 41 541 640  HOH HOH B . 
I 4 HOH 42 542 628  HOH HOH B . 
I 4 HOH 43 543 605  HOH HOH B . 
I 4 HOH 44 544 722  HOH HOH B . 
I 4 HOH 45 545 644  HOH HOH B . 
I 4 HOH 46 546 822  HOH HOH B . 
I 4 HOH 47 547 655  HOH HOH B . 
I 4 HOH 48 548 638  HOH HOH B . 
I 4 HOH 49 549 647  HOH HOH B . 
I 4 HOH 50 550 953  HOH HOH B . 
I 4 HOH 51 551 604  HOH HOH B . 
I 4 HOH 52 552 613  HOH HOH B . 
I 4 HOH 53 553 600  HOH HOH B . 
I 4 HOH 54 554 603  HOH HOH B . 
I 4 HOH 55 555 567  HOH HOH B . 
I 4 HOH 56 556 721  HOH HOH B . 
I 4 HOH 57 557 641  HOH HOH B . 
I 4 HOH 58 558 642  HOH HOH B . 
I 4 HOH 59 559 643  HOH HOH B . 
I 4 HOH 60 560 661  HOH HOH B . 
I 4 HOH 61 561 626  HOH HOH B . 
I 4 HOH 62 562 623  HOH HOH B . 
I 4 HOH 63 563 616  HOH HOH B . 
I 4 HOH 64 564 649  HOH HOH B . 
I 4 HOH 65 565 592  HOH HOH B . 
I 4 HOH 66 566 620  HOH HOH B . 
I 4 HOH 67 567 257  HOH HOH B . 
J 4 HOH 1  401 673  HOH HOH C . 
J 4 HOH 2  402 992  HOH HOH C . 
J 4 HOH 3  403 808  HOH HOH C . 
J 4 HOH 4  404 3    HOH HOH C . 
J 4 HOH 5  405 672  HOH HOH C . 
J 4 HOH 6  406 553  HOH HOH C . 
J 4 HOH 7  407 571  HOH HOH C . 
J 4 HOH 8  408 664  HOH HOH C . 
J 4 HOH 9  409 691  HOH HOH C . 
J 4 HOH 10 410 430  HOH HOH C . 
J 4 HOH 11 411 798  HOH HOH C . 
J 4 HOH 12 412 669  HOH HOH C . 
J 4 HOH 13 413 688  HOH HOH C . 
J 4 HOH 14 414 662  HOH HOH C . 
J 4 HOH 15 415 564  HOH HOH C . 
J 4 HOH 16 416 561  HOH HOH C . 
J 4 HOH 17 417 557  HOH HOH C . 
J 4 HOH 18 418 785  HOH HOH C . 
J 4 HOH 19 419 565  HOH HOH C . 
J 4 HOH 20 420 705  HOH HOH C . 
J 4 HOH 21 421 562  HOH HOH C . 
J 4 HOH 22 422 549  HOH HOH C . 
J 4 HOH 23 423 570  HOH HOH C . 
J 4 HOH 24 424 559  HOH HOH C . 
J 4 HOH 25 425 737  HOH HOH C . 
J 4 HOH 26 426 463  HOH HOH C . 
J 4 HOH 27 427 756  HOH HOH C . 
J 4 HOH 28 428 548  HOH HOH C . 
J 4 HOH 29 429 550  HOH HOH C . 
J 4 HOH 30 430 20   HOH HOH C . 
J 4 HOH 31 431 447  HOH HOH C . 
J 4 HOH 32 432 558  HOH HOH C . 
J 4 HOH 33 433 634  HOH HOH C . 
J 4 HOH 34 434 563  HOH HOH C . 
J 4 HOH 35 435 28   HOH HOH C . 
J 4 HOH 36 436 554  HOH HOH C . 
J 4 HOH 37 437 446  HOH HOH C . 
J 4 HOH 38 438 503  HOH HOH C . 
J 4 HOH 39 439 567  HOH HOH C . 
J 4 HOH 40 440 543  HOH HOH C . 
J 4 HOH 41 441 714  HOH HOH C . 
J 4 HOH 42 442 717  HOH HOH C . 
J 4 HOH 43 443 764  HOH HOH C . 
J 4 HOH 44 444 738  HOH HOH C . 
J 4 HOH 45 445 542  HOH HOH C . 
J 4 HOH 46 446 560  HOH HOH C . 
J 4 HOH 47 447 663  HOH HOH C . 
J 4 HOH 48 448 874  HOH HOH C . 
J 4 HOH 49 449 904  HOH HOH C . 
J 4 HOH 50 450 1255 HOH HOH C . 
J 4 HOH 51 451 473  HOH HOH C . 
J 4 HOH 52 452 578  HOH HOH C . 
J 4 HOH 53 453 1240 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ETA 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.164 
_cell.length_a_esd                 ? 
_cell.length_b                     133.63 
_cell.length_b_esd                 ? 
_cell.length_c                     147.675 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ETA 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ETA 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.81 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.18 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ETA 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.5 
_reflns.d_resolution_low                               99.282 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     51613 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.146 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.5 
_reflns_shell.d_res_low                                     2.58 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.2 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4396 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.7 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.851 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.051 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -3.110 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            2.322 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.788 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               54.478 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.950 
_refine.correlation_coeff_Fo_to_Fc_free          0.937 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ETA 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.512 
_refine.ls_d_res_low                             99.282 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     50452 
_refine.ls_number_reflns_R_free                  2583 
_refine.ls_number_reflns_R_work                  47869 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.198 
_refine.ls_percent_reflns_R_free                 5.120 
_refine.ls_R_factor_all                          0.220 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2401 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2184 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.232 
_refine.ls_wR_factor_R_work                      0.211 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.523 
_refine.pdbx_overall_ESU_R_Free                  0.271 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9626 
_refine.pdbx_average_fsc_free                    0.9547 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.512 
_refine_hist.d_res_low                        99.282 
_refine_hist.number_atoms_solvent             224 
_refine_hist.number_atoms_total               9259 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9023 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         12 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  9302  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.685  1.849  12637 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.174  5.000  1122  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 25.904 5.000  45    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.099 10.000 1622  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.501 10.000 403   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.105  0.200  1430  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  6976  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.223  0.200  4285  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.316  0.200  6342  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.126  0.200  318   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.218  0.200  59    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.166  0.200  14    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 3.321  5.303  4494  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.256  9.534  5614  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.738  5.553  4808  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 7.296  10.069 7023  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.514  57.903 13952 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.512  2.577  3714 . 161 3167 89.6069  . 1.493 . . 1.499 . . . . . 1.833 . 20 . 0.876 0.884 1.381 
'X-RAY DIFFRACTION' 2.577  2.648  3628 . 174 3454 100.0000 . 0.417 . . 0.417 . . . . . 0.424 . 20 . 0.942 0.918 0.428 
'X-RAY DIFFRACTION' 2.648  2.725  3521 . 186 3335 100.0000 . 0.316 . . 0.313 . . . . . 0.314 . 20 . 0.950 0.945 0.369 
'X-RAY DIFFRACTION' 2.725  2.808  3387 . 146 3240 99.9705  . 0.279 . . 0.278 . . . . . 0.274 . 20 . 0.956 0.952 0.285 
'X-RAY DIFFRACTION' 2.808  2.900  3339 . 173 3166 100.0000 . 0.263 . . 0.261 . . . . . 0.253 . 20 . 0.956 0.943 0.304 
'X-RAY DIFFRACTION' 2.900  3.002  3202 . 161 3041 100.0000 . 0.263 . . 0.260 . . . . . 0.253 . 20 . 0.956 0.934 0.310 
'X-RAY DIFFRACTION' 3.002  3.115  3114 . 176 2937 99.9679  . 0.247 . . 0.245 . . . . . 0.238 . 20 . 0.964 0.950 0.278 
'X-RAY DIFFRACTION' 3.115  3.242  2973 . 155 2818 100.0000 . 0.237 . . 0.236 . . . . . 0.230 . 20 . 0.968 0.959 0.257 
'X-RAY DIFFRACTION' 3.242  3.386  2887 . 142 2745 100.0000 . 0.227 . . 0.226 . . . . . 0.221 . 20 . 0.972 0.961 0.252 
'X-RAY DIFFRACTION' 3.386  3.551  2743 . 145 2598 100.0000 . 0.222 . . 0.221 . . . . . 0.219 . 20 . 0.976 0.973 0.234 
'X-RAY DIFFRACTION' 3.551  3.743  2618 . 128 2490 100.0000 . 0.205 . . 0.203 . . . . . 0.199 . 20 . 0.980 0.972 0.248 
'X-RAY DIFFRACTION' 3.743  3.970  2481 . 144 2337 100.0000 . 0.188 . . 0.188 . . . . . 0.185 . 20 . 0.984 0.976 0.200 
'X-RAY DIFFRACTION' 3.970  4.244  2362 . 131 2231 100.0000 . 0.171 . . 0.170 . . . . . 0.167 . 20 . 0.985 0.979 0.196 
'X-RAY DIFFRACTION' 4.244  4.583  2175 . 114 2061 100.0000 . 0.156 . . 0.154 . . . . . 0.152 . 20 . 0.987 0.978 0.202 
'X-RAY DIFFRACTION' 4.583  5.019  2024 . 105 1917 99.9012  . 0.150 . . 0.149 . . . . . 0.148 . 20 . 0.986 0.983 0.161 
'X-RAY DIFFRACTION' 5.019  5.610  1847 . 84  1762 99.9459  . 0.169 . . 0.168 . . . . . 0.167 . 20 . 0.985 0.979 0.195 
'X-RAY DIFFRACTION' 5.610  6.474  1642 . 80  1560 99.8782  . 0.195 . . 0.194 . . . . . 0.192 . 20 . 0.983 0.975 0.215 
'X-RAY DIFFRACTION' 6.474  7.921  1407 . 71  1335 99.9289  . 0.203 . . 0.204 . . . . . 0.205 . 20 . 0.981 0.980 0.182 
'X-RAY DIFFRACTION' 7.921  11.167 1118 . 63  1054 99.9106  . 0.139 . . 0.139 . . . . . 0.144 . 20 . 0.990 0.989 0.147 
'X-RAY DIFFRACTION' 11.167 99.282 667  . 44  621  99.7001  . 0.230 . . 0.227 . . . . . 0.278 . 20 . 0.967 0.968 0.276 
# 
_struct.entry_id                     9ETA 
_struct.title                        'CDK2-cyclin A in complex with FragLite 3' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ETA 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CCNA2_BOVIN P30274 ? 1 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
2 UNP CDK2_HUMAN  P24941 ? 2 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ETA D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
2 2 9ETA A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
3 1 9ETA B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
4 2 9ETA C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ETA GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 1  
1 9ETA HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 2  
1 9ETA HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 3  
1 9ETA HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 4  
1 9ETA HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 5  
1 9ETA HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 6  
1 9ETA HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 7  
2 9ETA GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  8  
2 9ETA PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  9  
2 9ETA GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  10 
2 9ETA SER A 4   ? UNP P24941 ? ? 'expression tag' 0   11 
3 9ETA GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 12 
3 9ETA HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 13 
3 9ETA HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 14 
3 9ETA HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 15 
3 9ETA HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 16 
3 9ETA HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 17 
3 9ETA HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 18 
4 9ETA GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  19 
4 9ETA PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  20 
4 9ETA GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  21 
4 9ETA SER C 4   ? UNP P24941 ? ? 'expression tag' 0   22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3700  ? 
1 MORE         -14   ? 
1 'SSA (A^2)'  23410 ? 
2 'ABSA (A^2)' 3630  ? 
2 MORE         -15   ? 
2 'SSA (A^2)'  23800 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,F,G,J 
2 1 B,C,E,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 1   ? VAL A 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P2  AA2 TYR A 8   ? CYS A 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P3  AA3 TYR A 29  ? GLN A 33  ? TYR D 199 GLN D 203 5 ? 5  
HELX_P HELX_P4  AA4 THR A 37  ? TYR A 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P5  AA5 GLN A 58  ? LEU A 73  ? GLN D 228 LEU D 243 1 ? 16 
HELX_P HELX_P6  AA6 LEU A 79  ? GLU A 99  ? LEU D 249 GLU D 269 1 ? 21 
HELX_P HELX_P7  AA7 GLU A 104 ? ILE A 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P8  AA8 THR A 117 ? LEU A 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P9  AA9 THR A 140 ? LEU A 150 ? THR D 310 LEU D 320 1 ? 11 
HELX_P HELX_P10 AB1 ASN A 156 ? ASP A 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P11 AB2 ASP A 173 ? LEU A 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P12 AB3 LEU A 181 ? THR A 198 ? LEU D 351 THR D 368 1 ? 18 
HELX_P HELX_P13 AB4 PRO A 203 ? GLY A 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P14 AB5 LEU A 217 ? ALA A 231 ? LEU D 387 ALA D 401 1 ? 15 
HELX_P HELX_P15 AB6 PRO A 232 ? HIS A 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P16 AB7 GLN A 237 ? TYR A 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P17 AB8 LYS A 244 ? HIS A 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P18 AB9 GLY A 250 ? LEU A 254 ? GLY D 420 LEU D 424 5 ? 5  
HELX_P HELX_P19 AC1 SER B 4   ? GLU B 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P20 AC2 PRO B 49  ? GLU B 61  ? PRO A 45  GLU A 57  1 ? 13 
HELX_P HELX_P21 AC3 LEU B 91  ? SER B 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P22 AC4 PRO B 104 ? HIS B 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P23 AC5 LYS B 133 ? GLN B 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P24 AC6 THR B 169 ? ARG B 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P25 AC7 ALA B 174 ? LEU B 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P26 AC8 THR B 186 ? ARG B 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P27 AC9 SER B 211 ? GLY B 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P28 AD1 GLY B 233 ? MET B 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P29 AD2 ASP B 251 ? VAL B 255 ? ASP A 247 VAL A 251 5 ? 5  
HELX_P HELX_P30 AD3 ASP B 260 ? LEU B 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P31 AD4 SER B 280 ? LEU B 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P32 AD5 ALA B 286 ? GLN B 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P33 AD6 GLY C 1   ? VAL C 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P34 AD7 TYR C 8   ? CYS C 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P35 AD8 GLY C 28  ? GLN C 33  ? GLY B 198 GLN B 203 5 ? 6  
HELX_P HELX_P36 AD9 THR C 37  ? TYR C 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P37 AE1 GLN C 58  ? MET C 76  ? GLN B 228 MET B 246 1 ? 19 
HELX_P HELX_P38 AE2 LEU C 79  ? GLY C 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P39 AE3 LYS C 82  ? GLU C 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P40 AE4 GLU C 104 ? THR C 112 ? GLU B 274 THR B 282 1 ? 9  
HELX_P HELX_P41 AE5 THR C 117 ? ALA C 133 ? THR B 287 ALA B 303 1 ? 17 
HELX_P HELX_P42 AE6 THR C 140 ? LEU C 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P43 AE7 ASN C 156 ? ASP C 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P44 AE8 ASP C 173 ? LEU C 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P45 AE9 LEU C 181 ? GLY C 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P46 AF1 PRO C 203 ? GLY C 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P47 AF2 THR C 213 ? ALA C 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P48 AF3 PRO C 232 ? HIS C 234 ? PRO B 402 HIS B 404 5 ? 3  
HELX_P HELX_P49 AF4 GLN C 237 ? TYR C 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P50 AF5 LYS C 244 ? HIS C 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P51 AF6 GLY C 250 ? LEU C 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P52 AF7 PRO D 49  ? LEU D 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P53 AF8 LEU D 91  ? SER D 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P54 AF9 PRO D 104 ? SER D 124 ? PRO C 100 SER C 120 1 ? 21 
HELX_P HELX_P55 AG1 LYS D 133 ? GLN D 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P56 AG2 THR D 169 ? ARG D 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P57 AG3 ALA D 174 ? LEU D 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P58 AG4 THR D 186 ? ARG D 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P59 AG5 SER D 211 ? GLY D 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P60 AG6 GLY D 233 ? MET D 237 ? GLY C 229 MET C 233 5 ? 5  
HELX_P HELX_P61 AG7 ASP D 251 ? VAL D 256 ? ASP C 247 VAL C 252 1 ? 6  
HELX_P HELX_P62 AG8 ASP D 260 ? LEU D 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P63 AG9 SER D 280 ? LEU D 285 ? SER C 276 LEU C 281 1 ? 6  
HELX_P HELX_P64 AH1 ALA D 286 ? VAL D 293 ? ALA C 282 VAL C 289 5 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? B TYR 163 C ? ? ? 1_555 B TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale2 covale both ? B TPO 164 C ? ? ? 1_555 B HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.348 ? ? 
covale3 covale both ? D TYR 163 C ? ? ? 1_555 D TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.342 ? ? 
covale4 covale both ? D TPO 164 C ? ? ? 1_555 D HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.351 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO B 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO D 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 153 A . ? GLN 323 D PRO 154 A ? PRO 324 D 1 2.60  
2 ASP 175 A . ? ASP 345 D PRO 176 A ? PRO 346 D 1 4.81  
3 VAL 158 B . ? VAL 154 A PRO 159 B ? PRO 155 A 1 3.31  
4 GLN 153 C . ? GLN 323 B PRO 154 C ? PRO 324 B 1 5.38  
5 ASP 175 C . ? ASP 345 B PRO 176 C ? PRO 346 B 1 5.80  
6 VAL 158 D . ? VAL 154 C PRO 159 D ? PRO 155 C 1 -3.16 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 8   ? GLU B 16  ? PHE A 4   GLU A 12  
AA1 2 VAL B 21  ? ASN B 27  ? VAL A 17  ASN A 23  
AA1 3 VAL B 33  ? ARG B 40  ? VAL A 29  ARG A 36  
AA1 4 LYS B 79  ? GLU B 85  ? LYS A 75  GLU A 81  
AA1 5 LEU B 70  ? HIS B 75  ? LEU A 66  HIS A 71  
AA2 1 GLN B 89  ? ASP B 90  ? GLN A 85  ASP A 86  
AA2 2 LEU B 137 ? ILE B 139 ? LEU A 133 ILE A 135 
AA2 3 ILE B 145 ? LEU B 147 ? ILE A 141 LEU A 143 
AA3 1 VAL B 127 ? LEU B 128 ? VAL A 123 LEU A 124 
AA3 2 ARG B 154 ? ALA B 155 ? ARG A 150 ALA A 151 
AA4 1 PHE D 8   ? GLU D 16  ? PHE C 4   GLU C 12  
AA4 2 VAL D 21  ? ASN D 27  ? VAL C 17  ASN C 23  
AA4 3 VAL D 33  ? ARG D 40  ? VAL C 29  ARG C 36  
AA4 4 LYS D 79  ? GLU D 85  ? LYS C 75  GLU C 81  
AA4 5 LEU D 70  ? HIS D 75  ? LEU C 66  HIS C 71  
AA5 1 GLN D 89  ? ASP D 90  ? GLN C 85  ASP C 86  
AA5 2 LEU D 137 ? ILE D 139 ? LEU C 133 ILE C 135 
AA5 3 ILE D 145 ? LEU D 147 ? ILE C 141 LEU C 143 
AA6 1 VAL D 127 ? LEU D 128 ? VAL C 123 LEU C 124 
AA6 2 ARG D 154 ? ALA D 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE B 14  ? N ILE A 10  O VAL B 22  ? O VAL A 18  
AA1 2 3 N ALA B 25  ? N ALA A 21  O VAL B 34  ? O VAL A 30  
AA1 3 4 N ALA B 35  ? N ALA A 31  O PHE B 84  ? O PHE A 80  
AA1 4 5 O VAL B 83  ? O VAL A 79  N LEU B 71  ? N LEU A 67  
AA2 1 2 N GLN B 89  ? N GLN A 85  O ILE B 139 ? O ILE A 135 
AA2 2 3 N LEU B 138 ? N LEU A 134 O LYS B 146 ? O LYS A 142 
AA3 1 2 N LEU B 128 ? N LEU A 124 O ARG B 154 ? O ARG A 150 
AA4 1 2 N GLY D 15  ? N GLY C 11  O VAL D 22  ? O VAL C 18  
AA4 2 3 N TYR D 23  ? N TYR C 19  O LEU D 36  ? O LEU C 32  
AA4 3 4 N ILE D 39  ? N ILE C 35  O LEU D 80  ? O LEU C 76  
AA4 4 5 O VAL D 83  ? O VAL C 79  N LEU D 71  ? N LEU C 67  
AA5 1 2 N GLN D 89  ? N GLN C 85  O ILE D 139 ? O ILE C 135 
AA5 2 3 N LEU D 138 ? N LEU C 134 O LYS D 146 ? O LYS C 142 
AA6 1 2 N LEU D 128 ? N LEU C 124 O ARG D 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ETA 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL D 175 ? ? 34.36   67.26   
2  1 GLN D 323 ? ? -164.61 92.50   
3  1 TRP D 372 ? ? -37.93  120.06  
4  1 LEU A 58  ? ? -100.34 75.38   
5  1 THR A 72  ? ? -95.45  -158.87 
6  1 ARG A 126 ? ? 80.32   14.58   
7  1 ASP A 127 ? ? -157.63 42.88   
8  1 ASP A 145 ? ? 61.19   88.41   
9  1 VAL A 164 ? ? 80.83   121.24  
10 1 SER A 181 ? ? -142.13 -147.39 
11 1 ASP A 223 ? ? -120.76 -166.84 
12 1 VAL B 175 ? ? 39.28   63.06   
13 1 TRP B 372 ? ? -36.29  117.50  
14 1 GLU C 12  ? ? -124.84 -162.66 
15 1 THR C 41  ? ? -120.78 -79.98  
16 1 ASP C 127 ? ? -150.34 43.19   
17 1 ASP C 145 ? ? 55.91   77.10   
18 1 VAL C 164 ? ? 70.71   128.57  
19 1 SER C 181 ? ? -144.49 -159.46 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG D 187 ? ? 0.108 'SIDE CHAIN' 
2  1 ARG D 241 ? ? 0.105 'SIDE CHAIN' 
3  1 ARG D 250 ? ? 0.233 'SIDE CHAIN' 
4  1 ARG A 122 ? ? 0.231 'SIDE CHAIN' 
5  1 ARG A 157 ? ? 0.215 'SIDE CHAIN' 
6  1 ARG A 297 ? ? 0.258 'SIDE CHAIN' 
7  1 ARG B 187 ? ? 0.104 'SIDE CHAIN' 
8  1 ARG B 241 ? ? 0.268 'SIDE CHAIN' 
9  1 ARG C 36  ? ? 0.122 'SIDE CHAIN' 
10 1 ARG C 122 ? ? 0.258 'SIDE CHAIN' 
11 1 ARG C 157 ? ? 0.095 'SIDE CHAIN' 
12 1 ARG C 245 ? ? 0.289 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 B TPO 164 A TPO 160 ? THR 'modified residue' 
2 D TPO 164 C TPO 160 ? THR 'modified residue' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 D VAL 432 ? A VAL 262 
2  1 Y 1 D HIS 433 ? A HIS 263 
3  1 Y 1 D HIS 434 ? A HIS 264 
4  1 Y 1 D HIS 435 ? A HIS 265 
5  1 Y 1 D HIS 436 ? A HIS 266 
6  1 Y 1 D HIS 437 ? A HIS 267 
7  1 Y 1 D HIS 438 ? A HIS 268 
8  1 Y 1 B HIS 433 ? C HIS 263 
9  1 Y 1 B HIS 434 ? C HIS 264 
10 1 Y 1 B HIS 435 ? C HIS 265 
11 1 Y 1 B HIS 436 ? C HIS 266 
12 1 Y 1 B HIS 437 ? C HIS 267 
13 1 Y 1 B HIS 438 ? C HIS 268 
14 1 Y 1 C GLY -3  ? D GLY 1   
15 1 Y 1 C PRO -2  ? D PRO 2   
16 1 Y 1 C GLY -1  ? D GLY 3   
17 1 Y 1 C ARG 297 ? D ARG 301 
18 1 Y 1 C LEU 298 ? D LEU 302 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
7ZX N1   N  Y N 1   
7ZX C3   C  Y N 2   
7ZX BR1  BR N N 3   
7ZX C1   C  Y N 4   
7ZX C2   C  Y N 5   
7ZX O1   O  Y N 6   
7ZX H1   H  N N 7   
7ZX H2   H  N N 8   
ALA N    N  N N 9   
ALA CA   C  N S 10  
ALA C    C  N N 11  
ALA O    O  N N 12  
ALA CB   C  N N 13  
ALA OXT  O  N N 14  
ALA H    H  N N 15  
ALA H2   H  N N 16  
ALA HA   H  N N 17  
ALA HB1  H  N N 18  
ALA HB2  H  N N 19  
ALA HB3  H  N N 20  
ALA HXT  H  N N 21  
ARG N    N  N N 22  
ARG CA   C  N S 23  
ARG C    C  N N 24  
ARG O    O  N N 25  
ARG CB   C  N N 26  
ARG CG   C  N N 27  
ARG CD   C  N N 28  
ARG NE   N  N N 29  
ARG CZ   C  N N 30  
ARG NH1  N  N N 31  
ARG NH2  N  N N 32  
ARG OXT  O  N N 33  
ARG H    H  N N 34  
ARG H2   H  N N 35  
ARG HA   H  N N 36  
ARG HB2  H  N N 37  
ARG HB3  H  N N 38  
ARG HG2  H  N N 39  
ARG HG3  H  N N 40  
ARG HD2  H  N N 41  
ARG HD3  H  N N 42  
ARG HE   H  N N 43  
ARG HH11 H  N N 44  
ARG HH12 H  N N 45  
ARG HH21 H  N N 46  
ARG HH22 H  N N 47  
ARG HXT  H  N N 48  
ASN N    N  N N 49  
ASN CA   C  N S 50  
ASN C    C  N N 51  
ASN O    O  N N 52  
ASN CB   C  N N 53  
ASN CG   C  N N 54  
ASN OD1  O  N N 55  
ASN ND2  N  N N 56  
ASN OXT  O  N N 57  
ASN H    H  N N 58  
ASN H2   H  N N 59  
ASN HA   H  N N 60  
ASN HB2  H  N N 61  
ASN HB3  H  N N 62  
ASN HD21 H  N N 63  
ASN HD22 H  N N 64  
ASN HXT  H  N N 65  
ASP N    N  N N 66  
ASP CA   C  N S 67  
ASP C    C  N N 68  
ASP O    O  N N 69  
ASP CB   C  N N 70  
ASP CG   C  N N 71  
ASP OD1  O  N N 72  
ASP OD2  O  N N 73  
ASP OXT  O  N N 74  
ASP H    H  N N 75  
ASP H2   H  N N 76  
ASP HA   H  N N 77  
ASP HB2  H  N N 78  
ASP HB3  H  N N 79  
ASP HD2  H  N N 80  
ASP HXT  H  N N 81  
CYS N    N  N N 82  
CYS CA   C  N R 83  
CYS C    C  N N 84  
CYS O    O  N N 85  
CYS CB   C  N N 86  
CYS SG   S  N N 87  
CYS OXT  O  N N 88  
CYS H    H  N N 89  
CYS H2   H  N N 90  
CYS HA   H  N N 91  
CYS HB2  H  N N 92  
CYS HB3  H  N N 93  
CYS HG   H  N N 94  
CYS HXT  H  N N 95  
GLN N    N  N N 96  
GLN CA   C  N S 97  
GLN C    C  N N 98  
GLN O    O  N N 99  
GLN CB   C  N N 100 
GLN CG   C  N N 101 
GLN CD   C  N N 102 
GLN OE1  O  N N 103 
GLN NE2  N  N N 104 
GLN OXT  O  N N 105 
GLN H    H  N N 106 
GLN H2   H  N N 107 
GLN HA   H  N N 108 
GLN HB2  H  N N 109 
GLN HB3  H  N N 110 
GLN HG2  H  N N 111 
GLN HG3  H  N N 112 
GLN HE21 H  N N 113 
GLN HE22 H  N N 114 
GLN HXT  H  N N 115 
GLU N    N  N N 116 
GLU CA   C  N S 117 
GLU C    C  N N 118 
GLU O    O  N N 119 
GLU CB   C  N N 120 
GLU CG   C  N N 121 
GLU CD   C  N N 122 
GLU OE1  O  N N 123 
GLU OE2  O  N N 124 
GLU OXT  O  N N 125 
GLU H    H  N N 126 
GLU H2   H  N N 127 
GLU HA   H  N N 128 
GLU HB2  H  N N 129 
GLU HB3  H  N N 130 
GLU HG2  H  N N 131 
GLU HG3  H  N N 132 
GLU HE2  H  N N 133 
GLU HXT  H  N N 134 
GLY N    N  N N 135 
GLY CA   C  N N 136 
GLY C    C  N N 137 
GLY O    O  N N 138 
GLY OXT  O  N N 139 
GLY H    H  N N 140 
GLY H2   H  N N 141 
GLY HA2  H  N N 142 
GLY HA3  H  N N 143 
GLY HXT  H  N N 144 
HIS N    N  N N 145 
HIS CA   C  N S 146 
HIS C    C  N N 147 
HIS O    O  N N 148 
HIS CB   C  N N 149 
HIS CG   C  Y N 150 
HIS ND1  N  Y N 151 
HIS CD2  C  Y N 152 
HIS CE1  C  Y N 153 
HIS NE2  N  Y N 154 
HIS OXT  O  N N 155 
HIS H    H  N N 156 
HIS H2   H  N N 157 
HIS HA   H  N N 158 
HIS HB2  H  N N 159 
HIS HB3  H  N N 160 
HIS HD1  H  N N 161 
HIS HD2  H  N N 162 
HIS HE1  H  N N 163 
HIS HE2  H  N N 164 
HIS HXT  H  N N 165 
HOH O    O  N N 166 
HOH H1   H  N N 167 
HOH H2   H  N N 168 
ILE N    N  N N 169 
ILE CA   C  N S 170 
ILE C    C  N N 171 
ILE O    O  N N 172 
ILE CB   C  N S 173 
ILE CG1  C  N N 174 
ILE CG2  C  N N 175 
ILE CD1  C  N N 176 
ILE OXT  O  N N 177 
ILE H    H  N N 178 
ILE H2   H  N N 179 
ILE HA   H  N N 180 
ILE HB   H  N N 181 
ILE HG12 H  N N 182 
ILE HG13 H  N N 183 
ILE HG21 H  N N 184 
ILE HG22 H  N N 185 
ILE HG23 H  N N 186 
ILE HD11 H  N N 187 
ILE HD12 H  N N 188 
ILE HD13 H  N N 189 
ILE HXT  H  N N 190 
LEU N    N  N N 191 
LEU CA   C  N S 192 
LEU C    C  N N 193 
LEU O    O  N N 194 
LEU CB   C  N N 195 
LEU CG   C  N N 196 
LEU CD1  C  N N 197 
LEU CD2  C  N N 198 
LEU OXT  O  N N 199 
LEU H    H  N N 200 
LEU H2   H  N N 201 
LEU HA   H  N N 202 
LEU HB2  H  N N 203 
LEU HB3  H  N N 204 
LEU HG   H  N N 205 
LEU HD11 H  N N 206 
LEU HD12 H  N N 207 
LEU HD13 H  N N 208 
LEU HD21 H  N N 209 
LEU HD22 H  N N 210 
LEU HD23 H  N N 211 
LEU HXT  H  N N 212 
LYS N    N  N N 213 
LYS CA   C  N S 214 
LYS C    C  N N 215 
LYS O    O  N N 216 
LYS CB   C  N N 217 
LYS CG   C  N N 218 
LYS CD   C  N N 219 
LYS CE   C  N N 220 
LYS NZ   N  N N 221 
LYS OXT  O  N N 222 
LYS H    H  N N 223 
LYS H2   H  N N 224 
LYS HA   H  N N 225 
LYS HB2  H  N N 226 
LYS HB3  H  N N 227 
LYS HG2  H  N N 228 
LYS HG3  H  N N 229 
LYS HD2  H  N N 230 
LYS HD3  H  N N 231 
LYS HE2  H  N N 232 
LYS HE3  H  N N 233 
LYS HZ1  H  N N 234 
LYS HZ2  H  N N 235 
LYS HZ3  H  N N 236 
LYS HXT  H  N N 237 
MET N    N  N N 238 
MET CA   C  N S 239 
MET C    C  N N 240 
MET O    O  N N 241 
MET CB   C  N N 242 
MET CG   C  N N 243 
MET SD   S  N N 244 
MET CE   C  N N 245 
MET OXT  O  N N 246 
MET H    H  N N 247 
MET H2   H  N N 248 
MET HA   H  N N 249 
MET HB2  H  N N 250 
MET HB3  H  N N 251 
MET HG2  H  N N 252 
MET HG3  H  N N 253 
MET HE1  H  N N 254 
MET HE2  H  N N 255 
MET HE3  H  N N 256 
MET HXT  H  N N 257 
PHE N    N  N N 258 
PHE CA   C  N S 259 
PHE C    C  N N 260 
PHE O    O  N N 261 
PHE CB   C  N N 262 
PHE CG   C  Y N 263 
PHE CD1  C  Y N 264 
PHE CD2  C  Y N 265 
PHE CE1  C  Y N 266 
PHE CE2  C  Y N 267 
PHE CZ   C  Y N 268 
PHE OXT  O  N N 269 
PHE H    H  N N 270 
PHE H2   H  N N 271 
PHE HA   H  N N 272 
PHE HB2  H  N N 273 
PHE HB3  H  N N 274 
PHE HD1  H  N N 275 
PHE HD2  H  N N 276 
PHE HE1  H  N N 277 
PHE HE2  H  N N 278 
PHE HZ   H  N N 279 
PHE HXT  H  N N 280 
PRO N    N  N N 281 
PRO CA   C  N S 282 
PRO C    C  N N 283 
PRO O    O  N N 284 
PRO CB   C  N N 285 
PRO CG   C  N N 286 
PRO CD   C  N N 287 
PRO OXT  O  N N 288 
PRO H    H  N N 289 
PRO HA   H  N N 290 
PRO HB2  H  N N 291 
PRO HB3  H  N N 292 
PRO HG2  H  N N 293 
PRO HG3  H  N N 294 
PRO HD2  H  N N 295 
PRO HD3  H  N N 296 
PRO HXT  H  N N 297 
SER N    N  N N 298 
SER CA   C  N S 299 
SER C    C  N N 300 
SER O    O  N N 301 
SER CB   C  N N 302 
SER OG   O  N N 303 
SER OXT  O  N N 304 
SER H    H  N N 305 
SER H2   H  N N 306 
SER HA   H  N N 307 
SER HB2  H  N N 308 
SER HB3  H  N N 309 
SER HG   H  N N 310 
SER HXT  H  N N 311 
THR N    N  N N 312 
THR CA   C  N S 313 
THR C    C  N N 314 
THR O    O  N N 315 
THR CB   C  N R 316 
THR OG1  O  N N 317 
THR CG2  C  N N 318 
THR OXT  O  N N 319 
THR H    H  N N 320 
THR H2   H  N N 321 
THR HA   H  N N 322 
THR HB   H  N N 323 
THR HG1  H  N N 324 
THR HG21 H  N N 325 
THR HG22 H  N N 326 
THR HG23 H  N N 327 
THR HXT  H  N N 328 
TPO N    N  N N 329 
TPO CA   C  N S 330 
TPO CB   C  N R 331 
TPO CG2  C  N N 332 
TPO OG1  O  N N 333 
TPO P    P  N N 334 
TPO O1P  O  N N 335 
TPO O2P  O  N N 336 
TPO O3P  O  N N 337 
TPO C    C  N N 338 
TPO O    O  N N 339 
TPO OXT  O  N N 340 
TPO H    H  N N 341 
TPO H2   H  N N 342 
TPO HA   H  N N 343 
TPO HB   H  N N 344 
TPO HG21 H  N N 345 
TPO HG22 H  N N 346 
TPO HG23 H  N N 347 
TPO HOP2 H  N N 348 
TPO HOP3 H  N N 349 
TPO HXT  H  N N 350 
TRP N    N  N N 351 
TRP CA   C  N S 352 
TRP C    C  N N 353 
TRP O    O  N N 354 
TRP CB   C  N N 355 
TRP CG   C  Y N 356 
TRP CD1  C  Y N 357 
TRP CD2  C  Y N 358 
TRP NE1  N  Y N 359 
TRP CE2  C  Y N 360 
TRP CE3  C  Y N 361 
TRP CZ2  C  Y N 362 
TRP CZ3  C  Y N 363 
TRP CH2  C  Y N 364 
TRP OXT  O  N N 365 
TRP H    H  N N 366 
TRP H2   H  N N 367 
TRP HA   H  N N 368 
TRP HB2  H  N N 369 
TRP HB3  H  N N 370 
TRP HD1  H  N N 371 
TRP HE1  H  N N 372 
TRP HE3  H  N N 373 
TRP HZ2  H  N N 374 
TRP HZ3  H  N N 375 
TRP HH2  H  N N 376 
TRP HXT  H  N N 377 
TYR N    N  N N 378 
TYR CA   C  N S 379 
TYR C    C  N N 380 
TYR O    O  N N 381 
TYR CB   C  N N 382 
TYR CG   C  Y N 383 
TYR CD1  C  Y N 384 
TYR CD2  C  Y N 385 
TYR CE1  C  Y N 386 
TYR CE2  C  Y N 387 
TYR CZ   C  Y N 388 
TYR OH   O  N N 389 
TYR OXT  O  N N 390 
TYR H    H  N N 391 
TYR H2   H  N N 392 
TYR HA   H  N N 393 
TYR HB2  H  N N 394 
TYR HB3  H  N N 395 
TYR HD1  H  N N 396 
TYR HD2  H  N N 397 
TYR HE1  H  N N 398 
TYR HE2  H  N N 399 
TYR HH   H  N N 400 
TYR HXT  H  N N 401 
VAL N    N  N N 402 
VAL CA   C  N S 403 
VAL C    C  N N 404 
VAL O    O  N N 405 
VAL CB   C  N N 406 
VAL CG1  C  N N 407 
VAL CG2  C  N N 408 
VAL OXT  O  N N 409 
VAL H    H  N N 410 
VAL H2   H  N N 411 
VAL HA   H  N N 412 
VAL HB   H  N N 413 
VAL HG11 H  N N 414 
VAL HG12 H  N N 415 
VAL HG13 H  N N 416 
VAL HG21 H  N N 417 
VAL HG22 H  N N 418 
VAL HG23 H  N N 419 
VAL HXT  H  N N 420 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
7ZX N1  C2   doub Y N 1   
7ZX N1  O1   sing Y N 2   
7ZX C2  C1   sing Y N 3   
7ZX C1  BR1  sing N N 4   
7ZX C1  C3   doub Y N 5   
7ZX O1  C3   sing Y N 6   
7ZX C3  H1   sing N N 7   
7ZX C2  H2   sing N N 8   
ALA N   CA   sing N N 9   
ALA N   H    sing N N 10  
ALA N   H2   sing N N 11  
ALA CA  C    sing N N 12  
ALA CA  CB   sing N N 13  
ALA CA  HA   sing N N 14  
ALA C   O    doub N N 15  
ALA C   OXT  sing N N 16  
ALA CB  HB1  sing N N 17  
ALA CB  HB2  sing N N 18  
ALA CB  HB3  sing N N 19  
ALA OXT HXT  sing N N 20  
ARG N   CA   sing N N 21  
ARG N   H    sing N N 22  
ARG N   H2   sing N N 23  
ARG CA  C    sing N N 24  
ARG CA  CB   sing N N 25  
ARG CA  HA   sing N N 26  
ARG C   O    doub N N 27  
ARG C   OXT  sing N N 28  
ARG CB  CG   sing N N 29  
ARG CB  HB2  sing N N 30  
ARG CB  HB3  sing N N 31  
ARG CG  CD   sing N N 32  
ARG CG  HG2  sing N N 33  
ARG CG  HG3  sing N N 34  
ARG CD  NE   sing N N 35  
ARG CD  HD2  sing N N 36  
ARG CD  HD3  sing N N 37  
ARG NE  CZ   sing N N 38  
ARG NE  HE   sing N N 39  
ARG CZ  NH1  sing N N 40  
ARG CZ  NH2  doub N N 41  
ARG NH1 HH11 sing N N 42  
ARG NH1 HH12 sing N N 43  
ARG NH2 HH21 sing N N 44  
ARG NH2 HH22 sing N N 45  
ARG OXT HXT  sing N N 46  
ASN N   CA   sing N N 47  
ASN N   H    sing N N 48  
ASN N   H2   sing N N 49  
ASN CA  C    sing N N 50  
ASN CA  CB   sing N N 51  
ASN CA  HA   sing N N 52  
ASN C   O    doub N N 53  
ASN C   OXT  sing N N 54  
ASN CB  CG   sing N N 55  
ASN CB  HB2  sing N N 56  
ASN CB  HB3  sing N N 57  
ASN CG  OD1  doub N N 58  
ASN CG  ND2  sing N N 59  
ASN ND2 HD21 sing N N 60  
ASN ND2 HD22 sing N N 61  
ASN OXT HXT  sing N N 62  
ASP N   CA   sing N N 63  
ASP N   H    sing N N 64  
ASP N   H2   sing N N 65  
ASP CA  C    sing N N 66  
ASP CA  CB   sing N N 67  
ASP CA  HA   sing N N 68  
ASP C   O    doub N N 69  
ASP C   OXT  sing N N 70  
ASP CB  CG   sing N N 71  
ASP CB  HB2  sing N N 72  
ASP CB  HB3  sing N N 73  
ASP CG  OD1  doub N N 74  
ASP CG  OD2  sing N N 75  
ASP OD2 HD2  sing N N 76  
ASP OXT HXT  sing N N 77  
CYS N   CA   sing N N 78  
CYS N   H    sing N N 79  
CYS N   H2   sing N N 80  
CYS CA  C    sing N N 81  
CYS CA  CB   sing N N 82  
CYS CA  HA   sing N N 83  
CYS C   O    doub N N 84  
CYS C   OXT  sing N N 85  
CYS CB  SG   sing N N 86  
CYS CB  HB2  sing N N 87  
CYS CB  HB3  sing N N 88  
CYS SG  HG   sing N N 89  
CYS OXT HXT  sing N N 90  
GLN N   CA   sing N N 91  
GLN N   H    sing N N 92  
GLN N   H2   sing N N 93  
GLN CA  C    sing N N 94  
GLN CA  CB   sing N N 95  
GLN CA  HA   sing N N 96  
GLN C   O    doub N N 97  
GLN C   OXT  sing N N 98  
GLN CB  CG   sing N N 99  
GLN CB  HB2  sing N N 100 
GLN CB  HB3  sing N N 101 
GLN CG  CD   sing N N 102 
GLN CG  HG2  sing N N 103 
GLN CG  HG3  sing N N 104 
GLN CD  OE1  doub N N 105 
GLN CD  NE2  sing N N 106 
GLN NE2 HE21 sing N N 107 
GLN NE2 HE22 sing N N 108 
GLN OXT HXT  sing N N 109 
GLU N   CA   sing N N 110 
GLU N   H    sing N N 111 
GLU N   H2   sing N N 112 
GLU CA  C    sing N N 113 
GLU CA  CB   sing N N 114 
GLU CA  HA   sing N N 115 
GLU C   O    doub N N 116 
GLU C   OXT  sing N N 117 
GLU CB  CG   sing N N 118 
GLU CB  HB2  sing N N 119 
GLU CB  HB3  sing N N 120 
GLU CG  CD   sing N N 121 
GLU CG  HG2  sing N N 122 
GLU CG  HG3  sing N N 123 
GLU CD  OE1  doub N N 124 
GLU CD  OE2  sing N N 125 
GLU OE2 HE2  sing N N 126 
GLU OXT HXT  sing N N 127 
GLY N   CA   sing N N 128 
GLY N   H    sing N N 129 
GLY N   H2   sing N N 130 
GLY CA  C    sing N N 131 
GLY CA  HA2  sing N N 132 
GLY CA  HA3  sing N N 133 
GLY C   O    doub N N 134 
GLY C   OXT  sing N N 135 
GLY OXT HXT  sing N N 136 
HIS N   CA   sing N N 137 
HIS N   H    sing N N 138 
HIS N   H2   sing N N 139 
HIS CA  C    sing N N 140 
HIS CA  CB   sing N N 141 
HIS CA  HA   sing N N 142 
HIS C   O    doub N N 143 
HIS C   OXT  sing N N 144 
HIS CB  CG   sing N N 145 
HIS CB  HB2  sing N N 146 
HIS CB  HB3  sing N N 147 
HIS CG  ND1  sing Y N 148 
HIS CG  CD2  doub Y N 149 
HIS ND1 CE1  doub Y N 150 
HIS ND1 HD1  sing N N 151 
HIS CD2 NE2  sing Y N 152 
HIS CD2 HD2  sing N N 153 
HIS CE1 NE2  sing Y N 154 
HIS CE1 HE1  sing N N 155 
HIS NE2 HE2  sing N N 156 
HIS OXT HXT  sing N N 157 
HOH O   H1   sing N N 158 
HOH O   H2   sing N N 159 
ILE N   CA   sing N N 160 
ILE N   H    sing N N 161 
ILE N   H2   sing N N 162 
ILE CA  C    sing N N 163 
ILE CA  CB   sing N N 164 
ILE CA  HA   sing N N 165 
ILE C   O    doub N N 166 
ILE C   OXT  sing N N 167 
ILE CB  CG1  sing N N 168 
ILE CB  CG2  sing N N 169 
ILE CB  HB   sing N N 170 
ILE CG1 CD1  sing N N 171 
ILE CG1 HG12 sing N N 172 
ILE CG1 HG13 sing N N 173 
ILE CG2 HG21 sing N N 174 
ILE CG2 HG22 sing N N 175 
ILE CG2 HG23 sing N N 176 
ILE CD1 HD11 sing N N 177 
ILE CD1 HD12 sing N N 178 
ILE CD1 HD13 sing N N 179 
ILE OXT HXT  sing N N 180 
LEU N   CA   sing N N 181 
LEU N   H    sing N N 182 
LEU N   H2   sing N N 183 
LEU CA  C    sing N N 184 
LEU CA  CB   sing N N 185 
LEU CA  HA   sing N N 186 
LEU C   O    doub N N 187 
LEU C   OXT  sing N N 188 
LEU CB  CG   sing N N 189 
LEU CB  HB2  sing N N 190 
LEU CB  HB3  sing N N 191 
LEU CG  CD1  sing N N 192 
LEU CG  CD2  sing N N 193 
LEU CG  HG   sing N N 194 
LEU CD1 HD11 sing N N 195 
LEU CD1 HD12 sing N N 196 
LEU CD1 HD13 sing N N 197 
LEU CD2 HD21 sing N N 198 
LEU CD2 HD22 sing N N 199 
LEU CD2 HD23 sing N N 200 
LEU OXT HXT  sing N N 201 
LYS N   CA   sing N N 202 
LYS N   H    sing N N 203 
LYS N   H2   sing N N 204 
LYS CA  C    sing N N 205 
LYS CA  CB   sing N N 206 
LYS CA  HA   sing N N 207 
LYS C   O    doub N N 208 
LYS C   OXT  sing N N 209 
LYS CB  CG   sing N N 210 
LYS CB  HB2  sing N N 211 
LYS CB  HB3  sing N N 212 
LYS CG  CD   sing N N 213 
LYS CG  HG2  sing N N 214 
LYS CG  HG3  sing N N 215 
LYS CD  CE   sing N N 216 
LYS CD  HD2  sing N N 217 
LYS CD  HD3  sing N N 218 
LYS CE  NZ   sing N N 219 
LYS CE  HE2  sing N N 220 
LYS CE  HE3  sing N N 221 
LYS NZ  HZ1  sing N N 222 
LYS NZ  HZ2  sing N N 223 
LYS NZ  HZ3  sing N N 224 
LYS OXT HXT  sing N N 225 
MET N   CA   sing N N 226 
MET N   H    sing N N 227 
MET N   H2   sing N N 228 
MET CA  C    sing N N 229 
MET CA  CB   sing N N 230 
MET CA  HA   sing N N 231 
MET C   O    doub N N 232 
MET C   OXT  sing N N 233 
MET CB  CG   sing N N 234 
MET CB  HB2  sing N N 235 
MET CB  HB3  sing N N 236 
MET CG  SD   sing N N 237 
MET CG  HG2  sing N N 238 
MET CG  HG3  sing N N 239 
MET SD  CE   sing N N 240 
MET CE  HE1  sing N N 241 
MET CE  HE2  sing N N 242 
MET CE  HE3  sing N N 243 
MET OXT HXT  sing N N 244 
PHE N   CA   sing N N 245 
PHE N   H    sing N N 246 
PHE N   H2   sing N N 247 
PHE CA  C    sing N N 248 
PHE CA  CB   sing N N 249 
PHE CA  HA   sing N N 250 
PHE C   O    doub N N 251 
PHE C   OXT  sing N N 252 
PHE CB  CG   sing N N 253 
PHE CB  HB2  sing N N 254 
PHE CB  HB3  sing N N 255 
PHE CG  CD1  doub Y N 256 
PHE CG  CD2  sing Y N 257 
PHE CD1 CE1  sing Y N 258 
PHE CD1 HD1  sing N N 259 
PHE CD2 CE2  doub Y N 260 
PHE CD2 HD2  sing N N 261 
PHE CE1 CZ   doub Y N 262 
PHE CE1 HE1  sing N N 263 
PHE CE2 CZ   sing Y N 264 
PHE CE2 HE2  sing N N 265 
PHE CZ  HZ   sing N N 266 
PHE OXT HXT  sing N N 267 
PRO N   CA   sing N N 268 
PRO N   CD   sing N N 269 
PRO N   H    sing N N 270 
PRO CA  C    sing N N 271 
PRO CA  CB   sing N N 272 
PRO CA  HA   sing N N 273 
PRO C   O    doub N N 274 
PRO C   OXT  sing N N 275 
PRO CB  CG   sing N N 276 
PRO CB  HB2  sing N N 277 
PRO CB  HB3  sing N N 278 
PRO CG  CD   sing N N 279 
PRO CG  HG2  sing N N 280 
PRO CG  HG3  sing N N 281 
PRO CD  HD2  sing N N 282 
PRO CD  HD3  sing N N 283 
PRO OXT HXT  sing N N 284 
SER N   CA   sing N N 285 
SER N   H    sing N N 286 
SER N   H2   sing N N 287 
SER CA  C    sing N N 288 
SER CA  CB   sing N N 289 
SER CA  HA   sing N N 290 
SER C   O    doub N N 291 
SER C   OXT  sing N N 292 
SER CB  OG   sing N N 293 
SER CB  HB2  sing N N 294 
SER CB  HB3  sing N N 295 
SER OG  HG   sing N N 296 
SER OXT HXT  sing N N 297 
THR N   CA   sing N N 298 
THR N   H    sing N N 299 
THR N   H2   sing N N 300 
THR CA  C    sing N N 301 
THR CA  CB   sing N N 302 
THR CA  HA   sing N N 303 
THR C   O    doub N N 304 
THR C   OXT  sing N N 305 
THR CB  OG1  sing N N 306 
THR CB  CG2  sing N N 307 
THR CB  HB   sing N N 308 
THR OG1 HG1  sing N N 309 
THR CG2 HG21 sing N N 310 
THR CG2 HG22 sing N N 311 
THR CG2 HG23 sing N N 312 
THR OXT HXT  sing N N 313 
TPO N   CA   sing N N 314 
TPO N   H    sing N N 315 
TPO N   H2   sing N N 316 
TPO CA  CB   sing N N 317 
TPO CA  C    sing N N 318 
TPO CA  HA   sing N N 319 
TPO CB  CG2  sing N N 320 
TPO CB  OG1  sing N N 321 
TPO CB  HB   sing N N 322 
TPO CG2 HG21 sing N N 323 
TPO CG2 HG22 sing N N 324 
TPO CG2 HG23 sing N N 325 
TPO OG1 P    sing N N 326 
TPO P   O1P  doub N N 327 
TPO P   O2P  sing N N 328 
TPO P   O3P  sing N N 329 
TPO O2P HOP2 sing N N 330 
TPO O3P HOP3 sing N N 331 
TPO C   O    doub N N 332 
TPO C   OXT  sing N N 333 
TPO OXT HXT  sing N N 334 
TRP N   CA   sing N N 335 
TRP N   H    sing N N 336 
TRP N   H2   sing N N 337 
TRP CA  C    sing N N 338 
TRP CA  CB   sing N N 339 
TRP CA  HA   sing N N 340 
TRP C   O    doub N N 341 
TRP C   OXT  sing N N 342 
TRP CB  CG   sing N N 343 
TRP CB  HB2  sing N N 344 
TRP CB  HB3  sing N N 345 
TRP CG  CD1  doub Y N 346 
TRP CG  CD2  sing Y N 347 
TRP CD1 NE1  sing Y N 348 
TRP CD1 HD1  sing N N 349 
TRP CD2 CE2  doub Y N 350 
TRP CD2 CE3  sing Y N 351 
TRP NE1 CE2  sing Y N 352 
TRP NE1 HE1  sing N N 353 
TRP CE2 CZ2  sing Y N 354 
TRP CE3 CZ3  doub Y N 355 
TRP CE3 HE3  sing N N 356 
TRP CZ2 CH2  doub Y N 357 
TRP CZ2 HZ2  sing N N 358 
TRP CZ3 CH2  sing Y N 359 
TRP CZ3 HZ3  sing N N 360 
TRP CH2 HH2  sing N N 361 
TRP OXT HXT  sing N N 362 
TYR N   CA   sing N N 363 
TYR N   H    sing N N 364 
TYR N   H2   sing N N 365 
TYR CA  C    sing N N 366 
TYR CA  CB   sing N N 367 
TYR CA  HA   sing N N 368 
TYR C   O    doub N N 369 
TYR C   OXT  sing N N 370 
TYR CB  CG   sing N N 371 
TYR CB  HB2  sing N N 372 
TYR CB  HB3  sing N N 373 
TYR CG  CD1  doub Y N 374 
TYR CG  CD2  sing Y N 375 
TYR CD1 CE1  sing Y N 376 
TYR CD1 HD1  sing N N 377 
TYR CD2 CE2  doub Y N 378 
TYR CD2 HD2  sing N N 379 
TYR CE1 CZ   doub Y N 380 
TYR CE1 HE1  sing N N 381 
TYR CE2 CZ   sing Y N 382 
TYR CE2 HE2  sing N N 383 
TYR CZ  OH   sing N N 384 
TYR OH  HH   sing N N 385 
TYR OXT HXT  sing N N 386 
VAL N   CA   sing N N 387 
VAL N   H    sing N N 388 
VAL N   H2   sing N N 389 
VAL CA  C    sing N N 390 
VAL CA  CB   sing N N 391 
VAL CA  HA   sing N N 392 
VAL C   O    doub N N 393 
VAL C   OXT  sing N N 394 
VAL CB  CG1  sing N N 395 
VAL CB  CG2  sing N N 396 
VAL CB  HB   sing N N 397 
VAL CG1 HG11 sing N N 398 
VAL CG1 HG12 sing N N 399 
VAL CG1 HG13 sing N N 400 
VAL CG2 HG21 sing N N 401 
VAL CG2 HG22 sing N N 402 
VAL CG2 HG23 sing N N 403 
VAL OXT HXT  sing N N 404 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ETA 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013484 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007483 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006772 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 -0.0750  
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P  15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2467   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0258   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLY A 1 1   ? -65.49  1.819   29.967  1    63.52  ? 171 GLY D N   1 
ATOM   2    C  CA  . GLY A 1 1   ? -64.878 2.797   30.878  1    64.7   ? 171 GLY D CA  1 
ATOM   3    C  C   . GLY A 1 1   ? -63.364 2.809   30.701  1    64.57  ? 171 GLY D C   1 
ATOM   4    O  O   . GLY A 1 1   ? -62.792 1.828   30.227  1    63.56  ? 171 GLY D O   1 
ATOM   5    N  N   . VAL A 1 2   ? -62.746 3.916   31.137  1    65.16  ? 172 VAL D N   1 
ATOM   6    C  CA  . VAL A 1 2   ? -61.385 4.287   30.793  1    63.05  ? 172 VAL D CA  1 
ATOM   7    C  C   . VAL A 1 2   ? -60.398 3.294   31.401  1    62.54  ? 172 VAL D C   1 
ATOM   8    O  O   . VAL A 1 2   ? -59.276 3.185   30.911  1    59.88  ? 172 VAL D O   1 
ATOM   9    C  CB  . VAL A 1 2   ? -61.05  5.735   31.196  1    64.72  ? 172 VAL D CB  1 
ATOM   10   C  CG1 . VAL A 1 2   ? -60.952 5.923   32.708  1    60.94  ? 172 VAL D CG1 1 
ATOM   11   C  CG2 . VAL A 1 2   ? -59.783 6.22    30.502  1    67.14  ? 172 VAL D CG2 1 
ATOM   12   N  N   . ASN A 1 3   ? -60.841 2.55    32.426  1    63.48  ? 173 ASN D N   1 
ATOM   13   C  CA  . ASN A 1 3   ? -60.052 1.483   33.028  1    59.19  ? 173 ASN D CA  1 
ATOM   14   C  C   . ASN A 1 3   ? -59.793 0.363   32.025  1    58.45  ? 173 ASN D C   1 
ATOM   15   O  O   . ASN A 1 3   ? -58.914 -0.463  32.255  1    55.72  ? 173 ASN D O   1 
ATOM   16   C  CB  . ASN A 1 3   ? -60.728 0.916   34.273  1    61.81  ? 173 ASN D CB  1 
ATOM   17   C  CG  . ASN A 1 3   ? -60.785 1.928   35.389  1    65     ? 173 ASN D CG  1 
ATOM   18   O  OD1 . ASN A 1 3   ? -60.043 2.917   35.361  1    65.56  ? 173 ASN D OD1 1 
ATOM   19   N  ND2 . ASN A 1 3   ? -61.635 1.695   36.377  1    67.96  ? 173 ASN D ND2 1 
ATOM   20   N  N   . GLU A 1 4   ? -60.606 0.289   30.959  1    64.85  ? 174 GLU D N   1 
ATOM   21   C  CA  . GLU A 1 4   ? -60.436 -0.746  29.95   1    68.24  ? 174 GLU D CA  1 
ATOM   22   C  C   . GLU A 1 4   ? -59.871 -0.131  28.674  1    70.07  ? 174 GLU D C   1 
ATOM   23   O  O   . GLU A 1 4   ? -59.836 -0.786  27.638  1    72.04  ? 174 GLU D O   1 
ATOM   24   C  CB  . GLU A 1 4   ? -61.753 -1.476  29.723  1    69.07  ? 174 GLU D CB  1 
ATOM   25   C  CG  . GLU A 1 4   ? -62.271 -2.165  30.98   1    72.11  ? 174 GLU D CG  1 
ATOM   26   C  CD  . GLU A 1 4   ? -63.634 -2.8    30.753  1    81.22  ? 174 GLU D CD  1 
ATOM   27   O  OE1 . GLU A 1 4   ? -64.214 -2.589  29.658  1    85.03  ? 174 GLU D OE1 1 
ATOM   28   O  OE2 . GLU A 1 4   ? -64.109 -3.514  31.665  1    80.62  ? 174 GLU D OE2 1 
ATOM   29   N  N   . VAL A 1 5   ? -59.41  1.128   28.794  1    70.23  ? 175 VAL D N   1 
ATOM   30   C  CA  . VAL A 1 5   ? -58.759 1.929   27.762  1    61.97  ? 175 VAL D CA  1 
ATOM   31   C  C   . VAL A 1 5   ? -59.371 1.588   26.408  1    62.78  ? 175 VAL D C   1 
ATOM   32   O  O   . VAL A 1 5   ? -58.714 0.979   25.567  1    63.03  ? 175 VAL D O   1 
ATOM   33   C  CB  . VAL A 1 5   ? -57.219 1.811   27.75   1    55.26  ? 175 VAL D CB  1 
ATOM   34   C  CG1 . VAL A 1 5   ? -56.585 2.426   28.998  1    49.94  ? 175 VAL D CG1 1 
ATOM   35   C  CG2 . VAL A 1 5   ? -56.756 0.379   27.518  1    51.1   ? 175 VAL D CG2 1 
ATOM   36   N  N   . PRO A 1 6   ? -60.661 1.93    26.176  1    63.95  ? 176 PRO D N   1 
ATOM   37   C  CA  . PRO A 1 6   ? -61.321 1.606   24.917  1    63.31  ? 176 PRO D CA  1 
ATOM   38   C  C   . PRO A 1 6   ? -60.648 2.243   23.698  1    65.48  ? 176 PRO D C   1 
ATOM   39   O  O   . PRO A 1 6   ? -60.568 1.634   22.637  1    71.37  ? 176 PRO D O   1 
ATOM   40   C  CB  . PRO A 1 6   ? -62.772 2.075   25.123  1    61.79  ? 176 PRO D CB  1 
ATOM   41   C  CG  . PRO A 1 6   ? -62.737 3.02    26.29   1    61.14  ? 176 PRO D CG  1 
ATOM   42   C  CD  . PRO A 1 6   ? -61.557 2.609   27.128  1    64.14  ? 176 PRO D CD  1 
ATOM   43   N  N   . ASP A 1 7   ? -60.133 3.463   23.836  1    64.84  ? 177 ASP D N   1 
ATOM   44   C  CA  . ASP A 1 7   ? -59.5   4.111   22.7    1    63.16  ? 177 ASP D CA  1 
ATOM   45   C  C   . ASP A 1 7   ? -58.141 3.487   22.362  1    59.74  ? 177 ASP D C   1 
ATOM   46   O  O   . ASP A 1 7   ? -57.55  3.884   21.358  1    58.04  ? 177 ASP D O   1 
ATOM   47   C  CB  . ASP A 1 7   ? -59.338 5.604   22.926  1    66.33  ? 177 ASP D CB  1 
ATOM   48   C  CG  . ASP A 1 7   ? -60.578 6.438   22.674  1    69.14  ? 177 ASP D CG  1 
ATOM   49   O  OD1 . ASP A 1 7   ? -61.208 6.234   21.625  1    71.93  ? 177 ASP D OD1 1 
ATOM   50   O  OD2 . ASP A 1 7   ? -60.878 7.298   23.521  1    72.6   ? 177 ASP D OD2 1 
ATOM   51   N  N   . TYR A 1 8   ? -57.64  2.541   23.187  1    55.7   ? 178 TYR D N   1 
ATOM   52   C  CA  . TYR A 1 8   ? -56.284 2.022   23.036  1    54.53  ? 178 TYR D CA  1 
ATOM   53   C  C   . TYR A 1 8   ? -56.198 0.493   23.051  1    57     ? 178 TYR D C   1 
ATOM   54   O  O   . TYR A 1 8   ? -55.129 -0.034  22.766  1    58.42  ? 178 TYR D O   1 
ATOM   55   C  CB  . TYR A 1 8   ? -55.317 2.601   24.078  1    50.43  ? 178 TYR D CB  1 
ATOM   56   C  CG  . TYR A 1 8   ? -55.204 4.109   23.98   1    52.03  ? 178 TYR D CG  1 
ATOM   57   C  CD1 . TYR A 1 8   ? -54.421 4.696   22.998  1    52.39  ? 178 TYR D CD1 1 
ATOM   58   C  CD2 . TYR A 1 8   ? -55.925 4.94    24.826  1    53.34  ? 178 TYR D CD2 1 
ATOM   59   C  CE1 . TYR A 1 8   ? -54.345 6.073   22.869  1    54.78  ? 178 TYR D CE1 1 
ATOM   60   C  CE2 . TYR A 1 8   ? -55.849 6.317   24.71   1    54.2   ? 178 TYR D CE2 1 
ATOM   61   C  CZ  . TYR A 1 8   ? -55.068 6.891   23.72   1    55.58  ? 178 TYR D CZ  1 
ATOM   62   O  OH  . TYR A 1 8   ? -54.994 8.256   23.574  1    57.19  ? 178 TYR D OH  1 
ATOM   63   N  N   . HIS A 1 9   ? -57.267 -0.244  23.393  1    61.06  ? 179 HIS D N   1 
ATOM   64   C  CA  . HIS A 1 9   ? -57.145 -1.694  23.6    1    63.19  ? 179 HIS D CA  1 
ATOM   65   C  C   . HIS A 1 9   ? -56.529 -2.379  22.372  1    59.16  ? 179 HIS D C   1 
ATOM   66   O  O   . HIS A 1 9   ? -55.643 -3.219  22.51   1    53.71  ? 179 HIS D O   1 
ATOM   67   C  CB  . HIS A 1 9   ? -58.42  -2.353  24.172  1    65.14  ? 179 HIS D CB  1 
ATOM   68   C  CG  . HIS A 1 9   ? -59.53  -2.591  23.191  1    78.92  ? 179 HIS D CG  1 
ATOM   69   N  ND1 . HIS A 1 9   ? -60.736 -1.918  23.228  1    90.16  ? 179 HIS D ND1 1 
ATOM   70   C  CD2 . HIS A 1 9   ? -59.625 -3.444  22.148  1    82.55  ? 179 HIS D CD2 1 
ATOM   71   C  CE1 . HIS A 1 9   ? -61.513 -2.335  22.23   1    90.98  ? 179 HIS D CE1 1 
ATOM   72   N  NE2 . HIS A 1 9   ? -60.857 -3.266  21.564  1    85.57  ? 179 HIS D NE2 1 
ATOM   73   N  N   . GLU A 1 10  ? -56.974 -1.975  21.173  1    59.35  ? 180 GLU D N   1 
ATOM   74   C  CA  . GLU A 1 10  ? -56.591 -2.586  19.908  1    61.3   ? 180 GLU D CA  1 
ATOM   75   C  C   . GLU A 1 10  ? -55.11  -2.319  19.626  1    62.39  ? 180 GLU D C   1 
ATOM   76   O  O   . GLU A 1 10  ? -54.35  -3.262  19.373  1    62.69  ? 180 GLU D O   1 
ATOM   77   C  CB  . GLU A 1 10  ? -57.518 -2.043  18.822  1    66.61  ? 180 GLU D CB  1 
ATOM   78   C  CG  . GLU A 1 10  ? -57.661 -2.899  17.562  1    74.04  ? 180 GLU D CG  1 
ATOM   79   C  CD  . GLU A 1 10  ? -58.368 -2.127  16.438  1    84.33  ? 180 GLU D CD  1 
ATOM   80   O  OE1 . GLU A 1 10  ? -58.697 -0.925  16.629  1    85.34  ? 180 GLU D OE1 1 
ATOM   81   O  OE2 . GLU A 1 10  ? -58.598 -2.703  15.349  1    85.14  ? 180 GLU D OE2 1 
ATOM   82   N  N   . ASP A 1 11  ? -54.702 -1.038  19.678  1    60.01  ? 181 ASP D N   1 
ATOM   83   C  CA  . ASP A 1 11  ? -53.296 -0.706  19.517  1    57.32  ? 181 ASP D CA  1 
ATOM   84   C  C   . ASP A 1 11  ? -52.446 -1.487  20.519  1    56.68  ? 181 ASP D C   1 
ATOM   85   O  O   . ASP A 1 11  ? -51.415 -2.025  20.13   1    61.41  ? 181 ASP D O   1 
ATOM   86   C  CB  . ASP A 1 11  ? -53.014 0.784   19.63   1    58.6   ? 181 ASP D CB  1 
ATOM   87   C  CG  . ASP A 1 11  ? -53.511 1.648   18.481  1    62.82  ? 181 ASP D CG  1 
ATOM   88   O  OD1 . ASP A 1 11  ? -54.014 1.042   17.495  1    59.09  ? 181 ASP D OD1 1 
ATOM   89   O  OD2 . ASP A 1 11  ? -53.374 2.915   18.591  1    61.17  ? 181 ASP D OD2 1 
ATOM   90   N  N   . ILE A 1 12  ? -52.886 -1.565  21.787  1    49.09  ? 182 ILE D N   1 
ATOM   91   C  CA  . ILE A 1 12  ? -52.063 -2.146  22.837  1    49.01  ? 182 ILE D CA  1 
ATOM   92   C  C   . ILE A 1 12  ? -51.821 -3.612  22.505  1    48.3   ? 182 ILE D C   1 
ATOM   93   O  O   . ILE A 1 12  ? -50.674 -4.041  22.448  1    48.26  ? 182 ILE D O   1 
ATOM   94   C  CB  . ILE A 1 12  ? -52.635 -1.917  24.259  1    48.61  ? 182 ILE D CB  1 
ATOM   95   C  CG1 . ILE A 1 12  ? -52.517 -0.457  24.684  1    49.44  ? 182 ILE D CG1 1 
ATOM   96   C  CG2 . ILE A 1 12  ? -51.92  -2.788  25.281  1    45.89  ? 182 ILE D CG2 1 
ATOM   97   C  CD1 . ILE A 1 12  ? -53.152 -0.136  26.026  1    50.48  ? 182 ILE D CD1 1 
ATOM   98   N  N   . HIS A 1 13  ? -52.917 -4.339  22.247  1    51.61  ? 183 HIS D N   1 
ATOM   99   C  CA  . HIS A 1 13  ? -52.937 -5.745  21.839  1    48.03  ? 183 HIS D CA  1 
ATOM   100  C  C   . HIS A 1 13  ? -51.995 -6.003  20.658  1    48.11  ? 183 HIS D C   1 
ATOM   101  O  O   . HIS A 1 13  ? -51.106 -6.853  20.759  1    46.11  ? 183 HIS D O   1 
ATOM   102  C  CB  . HIS A 1 13  ? -54.383 -6.204  21.613  1    49.75  ? 183 HIS D CB  1 
ATOM   103  C  CG  . HIS A 1 13  ? -54.477 -7.591  21.105  1    50.32  ? 183 HIS D CG  1 
ATOM   104  N  ND1 . HIS A 1 13  ? -54.364 -8.677  21.944  1    51.22  ? 183 HIS D ND1 1 
ATOM   105  C  CD2 . HIS A 1 13  ? -54.604 -8.068  19.873  1    49.15  ? 183 HIS D CD2 1 
ATOM   106  C  CE1 . HIS A 1 13  ? -54.418 -9.79   21.231  1    51.2   ? 183 HIS D CE1 1 
ATOM   107  N  NE2 . HIS A 1 13  ? -54.57  -9.432  19.977  1    52.26  ? 183 HIS D NE2 1 
ATOM   108  N  N   . THR A 1 14  ? -52.151 -5.218  19.571  1    48.1   ? 184 THR D N   1 
ATOM   109  C  CA  . THR A 1 14  ? -51.299 -5.327  18.391  1    47.34  ? 184 THR D CA  1 
ATOM   110  C  C   . THR A 1 14  ? -49.825 -5.176  18.779  1    49.72  ? 184 THR D C   1 
ATOM   111  O  O   . THR A 1 14  ? -48.965 -5.878  18.252  1    52.89  ? 184 THR D O   1 
ATOM   112  C  CB  . THR A 1 14  ? -51.731 -4.303  17.343  1    47.42  ? 184 THR D CB  1 
ATOM   113  O  OG1 . THR A 1 14  ? -53.006 -4.734  16.879  1    54.03  ? 184 THR D OG1 1 
ATOM   114  C  CG2 . THR A 1 14  ? -50.819 -4.255  16.13   1    43.56  ? 184 THR D CG2 1 
ATOM   115  N  N   . TYR A 1 15  ? -49.528 -4.295  19.728  1    48.15  ? 185 TYR D N   1 
ATOM   116  C  CA  . TYR A 1 15  ? -48.117 -4.046  20.125  1    45.67  ? 185 TYR D CA  1 
ATOM   117  C  C   . TYR A 1 15  ? -47.595 -5.201  20.964  1    44.56  ? 185 TYR D C   1 
ATOM   118  O  O   . TYR A 1 15  ? -46.471 -5.638  20.722  1    44.62  ? 185 TYR D O   1 
ATOM   119  C  CB  . TYR A 1 15  ? -48.043 -2.716  20.873  1    44.07  ? 185 TYR D CB  1 
ATOM   120  C  CG  . TYR A 1 15  ? -46.648 -2.331  21.336  1    47.05  ? 185 TYR D CG  1 
ATOM   121  C  CD1 . TYR A 1 15  ? -45.628 -2.126  20.42   1    47.02  ? 185 TYR D CD1 1 
ATOM   122  C  CD2 . TYR A 1 15  ? -46.357 -2.186  22.685  1    43.07  ? 185 TYR D CD2 1 
ATOM   123  C  CE1 . TYR A 1 15  ? -44.356 -1.779  20.83   1    47.11  ? 185 TYR D CE1 1 
ATOM   124  C  CE2 . TYR A 1 15  ? -45.087 -1.841  23.108  1    43.02  ? 185 TYR D CE2 1 
ATOM   125  C  CZ  . TYR A 1 15  ? -44.087 -1.633  22.178  1    49.48  ? 185 TYR D CZ  1 
ATOM   126  O  OH  . TYR A 1 15  ? -42.83  -1.296  22.572  1    48.55  ? 185 TYR D OH  1 
ATOM   127  N  N   . LEU A 1 16  ? -48.398 -5.69   21.905  1    42.85  ? 186 LEU D N   1 
ATOM   128  C  CA  . LEU A 1 16  ? -47.975 -6.797  22.798  1    42.27  ? 186 LEU D CA  1 
ATOM   129  C  C   . LEU A 1 16  ? -47.707 -8.054  21.968  1    43.19  ? 186 LEU D C   1 
ATOM   130  O  O   . LEU A 1 16  ? -46.838 -8.843  22.346  1    41.55  ? 186 LEU D O   1 
ATOM   131  C  CB  . LEU A 1 16  ? -49.049 -7.041  23.854  1    40.65  ? 186 LEU D CB  1 
ATOM   132  C  CG  . LEU A 1 16  ? -49.26  -5.941  24.894  1    42.64  ? 186 LEU D CG  1 
ATOM   133  C  CD1 . LEU A 1 16  ? -50.388 -6.362  25.81   1    42.14  ? 186 LEU D CD1 1 
ATOM   134  C  CD2 . LEU A 1 16  ? -47.993 -5.688  25.683  1    37.38  ? 186 LEU D CD2 1 
ATOM   135  N  N   . ARG A 1 17  ? -48.432 -8.211  20.871  1    46.29  ? 187 ARG D N   1 
ATOM   136  C  CA  . ARG A 1 17  ? -48.261 -9.39   19.996  1    47.57  ? 187 ARG D CA  1 
ATOM   137  C  C   . ARG A 1 17  ? -46.911 -9.284  19.292  1    49.71  ? 187 ARG D C   1 
ATOM   138  O  O   . ARG A 1 17  ? -46.231 -10.304 19.14   1    49.79  ? 187 ARG D O   1 
ATOM   139  C  CB  . ARG A 1 17  ? -49.438 -9.444  19.02   1    45.66  ? 187 ARG D CB  1 
ATOM   140  C  CG  . ARG A 1 17  ? -50.769 -9.826  19.646  1    45.62  ? 187 ARG D CG  1 
ATOM   141  C  CD  . ARG A 1 17  ? -50.816 -11.298 19.993  1    45.22  ? 187 ARG D CD  1 
ATOM   142  N  NE  . ARG A 1 17  ? -50.721 -12.139 18.797  1    49.73  ? 187 ARG D NE  1 
ATOM   143  C  CZ  . ARG A 1 17  ? -51.757 -12.505 18.059  1    50.66  ? 187 ARG D CZ  1 
ATOM   144  N  NH1 . ARG A 1 17  ? -52.969 -12.515 18.58   1    52.92  ? 187 ARG D NH1 1 
ATOM   145  N  NH2 . ARG A 1 17  ? -51.572 -12.875 16.808  1    47.26  ? 187 ARG D NH2 1 
ATOM   146  N  N   . GLU A 1 18  ? -46.557 -8.077  18.876  1    48.75  ? 188 GLU D N   1 
ATOM   147  C  CA  . GLU A 1 18  ? -45.258 -7.872  18.2    1    50.57  ? 188 GLU D CA  1 
ATOM   148  C  C   . GLU A 1 18  ? -44.168 -7.975  19.264  1    48.81  ? 188 GLU D C   1 
ATOM   149  O  O   . GLU A 1 18  ? -43.081 -8.483  18.963  1    48.35  ? 188 GLU D O   1 
ATOM   150  C  CB  . GLU A 1 18  ? -45.321 -6.545  17.446  1    53.33  ? 188 GLU D CB  1 
ATOM   151  C  CG  . GLU A 1 18  ? -44.077 -6.215  16.631  1    63.8   ? 188 GLU D CG  1 
ATOM   152  C  CD  . GLU A 1 18  ? -44.24  -4.91   15.877  1    71.43  ? 188 GLU D CD  1 
ATOM   153  O  OE1 . GLU A 1 18  ? -45.3   -4.268  16.032  1    65.36  ? 188 GLU D OE1 1 
ATOM   154  O  OE2 . GLU A 1 18  ? -43.31  -4.541  15.133  1    64.97  ? 188 GLU D OE2 1 
ATOM   155  N  N   . MET A 1 19  ? -44.485 -7.553  20.481  1    47.09  ? 189 MET D N   1 
ATOM   156  C  CA  . MET A 1 19  ? -43.44  -7.547  21.485  1    49.15  ? 189 MET D CA  1 
ATOM   157  C  C   . MET A 1 19  ? -43.15  -8.931  22.06   1    49.2   ? 189 MET D C   1 
ATOM   158  O  O   . MET A 1 19  ? -42.014 -9.204  22.435  1    51.19  ? 189 MET D O   1 
ATOM   159  C  CB  . MET A 1 19  ? -43.787 -6.536  22.578  1    45.18  ? 189 MET D CB  1 
ATOM   160  C  CG  . MET A 1 19  ? -43.665 -5.116  22.08   1    53.54  ? 189 MET D CG  1 
ATOM   161  S  SD  . MET A 1 19  ? -41.98  -4.617  21.652  1    56.06  ? 189 MET D SD  1 
ATOM   162  C  CE  . MET A 1 19  ? -41.217 -5.116  23.221  1    59.15  ? 189 MET D CE  1 
ATOM   163  N  N   . GLU A 1 20  ? -44.175 -9.785  22.166  1    49.12  ? 190 GLU D N   1 
ATOM   164  C  CA  . GLU A 1 20  ? -44.022 -11.133 22.701  1    49.52  ? 190 GLU D CA  1 
ATOM   165  C  C   . GLU A 1 20  ? -43.135 -11.999 21.79   1    52.09  ? 190 GLU D C   1 
ATOM   166  O  O   . GLU A 1 20  ? -42.606 -13.02  22.218  1    57.84  ? 190 GLU D O   1 
ATOM   167  C  CB  . GLU A 1 20  ? -45.373 -11.824 22.925  1    46.48  ? 190 GLU D CB  1 
ATOM   168  C  CG  . GLU A 1 20  ? -46.133 -12.151 21.638  1    45.87  ? 190 GLU D CG  1 
ATOM   169  C  CD  . GLU A 1 20  ? -47.382 -13.023 21.825  1    50.62  ? 190 GLU D CD  1 
ATOM   170  O  OE1 . GLU A 1 20  ? -47.643 -13.461 22.99   1    44.63  ? 190 GLU D OE1 1 
ATOM   171  O  OE2 . GLU A 1 20  ? -48.109 -13.248 20.805  1    51.09  ? 190 GLU D OE2 1 
ATOM   172  N  N   . VAL A 1 21  ? -43.014 -11.62  20.518  1    50.51  ? 191 VAL D N   1 
ATOM   173  C  CA  . VAL A 1 21  ? -42.107 -12.261 19.588  1    52.21  ? 191 VAL D CA  1 
ATOM   174  C  C   . VAL A 1 21  ? -40.66  -11.832 19.862  1    56     ? 191 VAL D C   1 
ATOM   175  O  O   . VAL A 1 21  ? -39.746 -12.622 19.646  1    55.42  ? 191 VAL D O   1 
ATOM   176  C  CB  . VAL A 1 21  ? -42.504 -11.902 18.136  1    52.96  ? 191 VAL D CB  1 
ATOM   177  C  CG1 . VAL A 1 21  ? -41.413 -12.272 17.131  1    47.54  ? 191 VAL D CG1 1 
ATOM   178  C  CG2 . VAL A 1 21  ? -43.853 -12.476 17.714  1    45.8   ? 191 VAL D CG2 1 
ATOM   179  N  N   . LYS A 1 22  ? -40.432 -10.573 20.263  1    55.34  ? 192 LYS D N   1 
ATOM   180  C  CA  . LYS A 1 22  ? -39.062 -10.13  20.454  1    60.17  ? 192 LYS D CA  1 
ATOM   181  C  C   . LYS A 1 22  ? -38.573 -10.569 21.828  1    51.19  ? 192 LYS D C   1 
ATOM   182  O  O   . LYS A 1 22  ? -37.383 -10.731 22.011  1    55.13  ? 192 LYS D O   1 
ATOM   183  C  CB  . LYS A 1 22  ? -38.847 -8.635  20.164  1    79.91  ? 192 LYS D CB  1 
ATOM   184  C  CG  . LYS A 1 22  ? -39.006 -8.141  18.706  1    95.53  ? 192 LYS D CG  1 
ATOM   185  C  CD  . LYS A 1 22  ? -38.807 -6.641  18.465  1    100.33 ? 192 LYS D CD  1 
ATOM   186  C  CE  . LYS A 1 22  ? -38.948 -6.2    17.025  1    101.9  ? 192 LYS D CE  1 
ATOM   187  N  NZ  . LYS A 1 22  ? -38.78  -4.759  16.793  1    88.31  ? 192 LYS D NZ  1 
ATOM   188  N  N   . CYS A 1 23  ? -39.485 -10.767 22.784  1    50.59  ? 193 CYS D N   1 
ATOM   189  C  CA  . CYS A 1 23  ? -39.1   -11.2   24.131  1    53.11  ? 193 CYS D CA  1 
ATOM   190  C  C   . CYS A 1 23  ? -39.125 -12.729 24.24   1    52.03  ? 193 CYS D C   1 
ATOM   191  O  O   . CYS A 1 23  ? -39.087 -13.285 25.342  1    49.12  ? 193 CYS D O   1 
ATOM   192  C  CB  . CYS A 1 23  ? -39.988 -10.603 25.229  1    49.54  ? 193 CYS D CB  1 
ATOM   193  S  SG  . CYS A 1 23  ? -39.832 -8.807  25.442  1    58.87  ? 193 CYS D SG  1 
ATOM   194  N  N   . LYS A 1 24  ? -39.213 -13.408 23.09   1    55.27  ? 194 LYS D N   1 
ATOM   195  C  CA  . LYS A 1 24  ? -39.446 -14.842 23.077  1    55.57  ? 194 LYS D CA  1 
ATOM   196  C  C   . LYS A 1 24  ? -38.112 -15.521 23.352  1    55.41  ? 194 LYS D C   1 
ATOM   197  O  O   . LYS A 1 24  ? -37.113 -15.217 22.701  1    51.65  ? 194 LYS D O   1 
ATOM   198  C  CB  . LYS A 1 24  ? -39.969 -15.261 21.7    1    61.36  ? 194 LYS D CB  1 
ATOM   199  C  CG  . LYS A 1 24  ? -41.008 -16.356 21.655  1    65.22  ? 194 LYS D CG  1 
ATOM   200  C  CD  . LYS A 1 24  ? -40.504 -17.772 21.877  1    71.54  ? 194 LYS D CD  1 
ATOM   201  C  CE  . LYS A 1 24  ? -41.468 -18.773 21.304  1    81.58  ? 194 LYS D CE  1 
ATOM   202  N  NZ  . LYS A 1 24  ? -41.572 -18.66  19.842  1    75.64  ? 194 LYS D NZ  1 
ATOM   203  N  N   . PRO A 1 25  ? -38.055 -16.438 24.346  1    55.12  ? 195 PRO D N   1 
ATOM   204  C  CA  . PRO A 1 25  ? -36.825 -17.191 24.617  1    51.77  ? 195 PRO D CA  1 
ATOM   205  C  C   . PRO A 1 25  ? -36.59  -18.159 23.474  1    50.09  ? 195 PRO D C   1 
ATOM   206  O  O   . PRO A 1 25  ? -37.539 -18.523 22.8    1    53.02  ? 195 PRO D O   1 
ATOM   207  C  CB  . PRO A 1 25  ? -37.092 -17.956 25.904  1    52.19  ? 195 PRO D CB  1 
ATOM   208  C  CG  . PRO A 1 25  ? -38.431 -17.426 26.413  1    55.23  ? 195 PRO D CG  1 
ATOM   209  C  CD  . PRO A 1 25  ? -39.174 -16.8   25.241  1    53.44  ? 195 PRO D CD  1 
ATOM   210  N  N   . LYS A 1 26  ? -35.34  -18.583 23.288  1    50.71  ? 196 LYS D N   1 
ATOM   211  C  CA  . LYS A 1 26  ? -35.038 -19.641 22.339  1    55.46  ? 196 LYS D CA  1 
ATOM   212  C  C   . LYS A 1 26  ? -35.668 -20.951 22.821  1    56.07  ? 196 LYS D C   1 
ATOM   213  O  O   . LYS A 1 26  ? -35.33  -21.431 23.9    1    63.49  ? 196 LYS D O   1 
ATOM   214  C  CB  . LYS A 1 26  ? -33.52  -19.75  22.134  1    58.73  ? 196 LYS D CB  1 
ATOM   215  C  CG  . LYS A 1 26  ? -32.886 -18.693 21.216  1    69.69  ? 196 LYS D CG  1 
ATOM   216  C  CD  . LYS A 1 26  ? -31.375 -18.471 21.366  1    78.12  ? 196 LYS D CD  1 
ATOM   217  C  CE  . LYS A 1 26  ? -30.41  -19.532 20.874  1    85.31  ? 196 LYS D CE  1 
ATOM   218  N  NZ  . LYS A 1 26  ? -30.381 -20.76  21.676  1    78.5   ? 196 LYS D NZ  1 
ATOM   219  N  N   . VAL A 1 27  ? -36.593 -21.515 22.027  1    53.43  ? 197 VAL D N   1 
ATOM   220  C  CA  . VAL A 1 27  ? -37.093 -22.879 22.185  1    54.23  ? 197 VAL D CA  1 
ATOM   221  C  C   . VAL A 1 27  ? -35.919 -23.857 22.271  1    51     ? 197 VAL D C   1 
ATOM   222  O  O   . VAL A 1 27  ? -35.023 -23.845 21.435  1    49.87  ? 197 VAL D O   1 
ATOM   223  C  CB  . VAL A 1 27  ? -38.008 -23.293 21.009  1    56.49  ? 197 VAL D CB  1 
ATOM   224  C  CG1 . VAL A 1 27  ? -38.752 -24.581 21.315  1    59.08  ? 197 VAL D CG1 1 
ATOM   225  C  CG2 . VAL A 1 27  ? -39.009 -22.21  20.629  1    58.14  ? 197 VAL D CG2 1 
ATOM   226  N  N   . GLY A 1 28  ? -35.951 -24.761 23.248  1    55.27  ? 198 GLY D N   1 
ATOM   227  C  CA  . GLY A 1 28  ? -34.891 -25.758 23.363  1    62.97  ? 198 GLY D CA  1 
ATOM   228  C  C   . GLY A 1 28  ? -33.502 -25.123 23.492  1    63.11  ? 198 GLY D C   1 
ATOM   229  O  O   . GLY A 1 28  ? -32.547 -25.526 22.821  1    58.44  ? 198 GLY D O   1 
ATOM   230  N  N   . TYR A 1 29  ? -33.408 -24.111 24.37   1    60.56  ? 199 TYR D N   1 
ATOM   231  C  CA  . TYR A 1 29  ? -32.122 -23.612 24.828  1    55.09  ? 199 TYR D CA  1 
ATOM   232  C  C   . TYR A 1 29  ? -31.556 -24.655 25.787  1    55.17  ? 199 TYR D C   1 
ATOM   233  O  O   . TYR A 1 29  ? -30.347 -24.699 26.02   1    51.81  ? 199 TYR D O   1 
ATOM   234  C  CB  . TYR A 1 29  ? -32.24  -22.232 25.488  1    48.06  ? 199 TYR D CB  1 
ATOM   235  C  CG  . TYR A 1 29  ? -32.959 -22.184 26.831  1    45.55  ? 199 TYR D CG  1 
ATOM   236  C  CD1 . TYR A 1 29  ? -32.376 -22.723 27.983  1    48.41  ? 199 TYR D CD1 1 
ATOM   237  C  CD2 . TYR A 1 29  ? -34.214 -21.592 26.965  1    43.59  ? 199 TYR D CD2 1 
ATOM   238  C  CE1 . TYR A 1 29  ? -33.008 -22.686 29.221  1    45.45  ? 199 TYR D CE1 1 
ATOM   239  C  CE2 . TYR A 1 29  ? -34.864 -21.561 28.194  1    44.71  ? 199 TYR D CE2 1 
ATOM   240  C  CZ  . TYR A 1 29  ? -34.253 -22.087 29.328  1    46.07  ? 199 TYR D CZ  1 
ATOM   241  O  OH  . TYR A 1 29  ? -34.886 -22.046 30.538  1    47.66  ? 199 TYR D OH  1 
ATOM   242  N  N   . MET A 1 30  ? -32.458 -25.499 26.309  1    53.47  ? 200 MET D N   1 
ATOM   243  C  CA  . MET A 1 30  ? -32.123 -26.41  27.388  1    57.2   ? 200 MET D CA  1 
ATOM   244  C  C   . MET A 1 30  ? -31.093 -27.438 26.903  1    61     ? 200 MET D C   1 
ATOM   245  O  O   . MET A 1 30  ? -30.205 -27.847 27.662  1    58.38  ? 200 MET D O   1 
ATOM   246  C  CB  . MET A 1 30  ? -33.391 -27.06  27.958  1    58.66  ? 200 MET D CB  1 
ATOM   247  C  CG  . MET A 1 30  ? -33.225 -27.54  29.396  1    62.41  ? 200 MET D CG  1 
ATOM   248  S  SD  . MET A 1 30  ? -32.349 -26.391 30.482  1    61.2   ? 200 MET D SD  1 
ATOM   249  C  CE  . MET A 1 30  ? -33.713 -25.582 31.315  1    59.58  ? 200 MET D CE  1 
ATOM   250  N  N   . LYS A 1 31  ? -31.215 -27.861 25.636  1    60.65  ? 201 LYS D N   1 
ATOM   251  C  CA  . LYS A 1 31  ? -30.32  -28.878 25.113  1    62.6   ? 201 LYS D CA  1 
ATOM   252  C  C   . LYS A 1 31  ? -28.917 -28.297 25.009  1    60.74  ? 201 LYS D C   1 
ATOM   253  O  O   . LYS A 1 31  ? -27.942 -29.042 24.989  1    69.42  ? 201 LYS D O   1 
ATOM   254  C  CB  . LYS A 1 31  ? -30.684 -29.335 23.698  1    71.9   ? 201 LYS D CB  1 
ATOM   255  C  CG  . LYS A 1 31  ? -32.096 -29.823 23.494  1    79.6   ? 201 LYS D CG  1 
ATOM   256  C  CD  . LYS A 1 31  ? -32.549 -29.65  22.047  1    87.12  ? 201 LYS D CD  1 
ATOM   257  C  CE  . LYS A 1 31  ? -34.05  -29.695 21.903  1    89.02  ? 201 LYS D CE  1 
ATOM   258  N  NZ  . LYS A 1 31  ? -34.486 -29.964 20.53   1    97.68  ? 201 LYS D NZ  1 
ATOM   259  N  N   . LYS A 1 32  ? -28.836 -26.965 24.931  1    57.05  ? 202 LYS D N   1 
ATOM   260  C  CA  . LYS A 1 32  ? -27.586 -26.258 24.703  1    57.74  ? 202 LYS D CA  1 
ATOM   261  C  C   . LYS A 1 32  ? -26.947 -25.824 26.023  1    54.61  ? 202 LYS D C   1 
ATOM   262  O  O   . LYS A 1 32  ? -25.821 -25.342 26.003  1    56.19  ? 202 LYS D O   1 
ATOM   263  C  CB  . LYS A 1 32  ? -27.852 -25.073 23.769  1    66.1   ? 202 LYS D CB  1 
ATOM   264  C  CG  . LYS A 1 32  ? -28.653 -25.411 22.512  1    74.24  ? 202 LYS D CG  1 
ATOM   265  C  CD  . LYS A 1 32  ? -28.851 -24.293 21.493  1    82.22  ? 202 LYS D CD  1 
ATOM   266  C  CE  . LYS A 1 32  ? -29.921 -24.607 20.474  1    87.94  ? 202 LYS D CE  1 
ATOM   267  N  NZ  . LYS A 1 32  ? -29.913 -23.757 19.279  1    84.56  ? 202 LYS D NZ  1 
ATOM   268  N  N   . GLN A 1 33  ? -27.684 -25.978 27.141  1    52.41  ? 203 GLN D N   1 
ATOM   269  C  CA  . GLN A 1 33  ? -27.18  -25.85  28.506  1    47.71  ? 203 GLN D CA  1 
ATOM   270  C  C   . GLN A 1 33  ? -26.601 -27.187 28.991  1    53.17  ? 203 GLN D C   1 
ATOM   271  O  O   . GLN A 1 33  ? -27.339 -28.135 29.31   1    54.16  ? 203 GLN D O   1 
ATOM   272  C  CB  . GLN A 1 33  ? -28.314 -25.49  29.46   1    43.19  ? 203 GLN D CB  1 
ATOM   273  C  CG  . GLN A 1 33  ? -28.834 -24.069 29.332  1    45.24  ? 203 GLN D CG  1 
ATOM   274  C  CD  . GLN A 1 33  ? -27.868 -23.056 29.912  1    47.89  ? 203 GLN D CD  1 
ATOM   275  O  OE1 . GLN A 1 33  ? -26.829 -23.397 30.482  1    51.41  ? 203 GLN D OE1 1 
ATOM   276  N  NE2 . GLN A 1 33  ? -28.171 -21.783 29.735  1    46.18  ? 203 GLN D NE2 1 
ATOM   277  N  N   . PRO A 1 34  ? -25.256 -27.322 29.094  1    53.43  ? 204 PRO D N   1 
ATOM   278  C  CA  . PRO A 1 34  ? -24.657 -28.61  29.429  1    54.69  ? 204 PRO D CA  1 
ATOM   279  C  C   . PRO A 1 34  ? -25.028 -29.129 30.814  1    55.24  ? 204 PRO D C   1 
ATOM   280  O  O   . PRO A 1 34  ? -25.064 -30.334 31.041  1    63.7   ? 204 PRO D O   1 
ATOM   281  C  CB  . PRO A 1 34  ? -23.148 -28.359 29.308  1    54.83  ? 204 PRO D CB  1 
ATOM   282  C  CG  . PRO A 1 34  ? -23.029 -27.061 28.534  1    56.25  ? 204 PRO D CG  1 
ATOM   283  C  CD  . PRO A 1 34  ? -24.255 -26.259 28.893  1    53.46  ? 204 PRO D CD  1 
ATOM   284  N  N   . ASP A 1 35  ? -25.277 -28.212 31.741  1    56.47  ? 205 ASP D N   1 
ATOM   285  C  CA  . ASP A 1 35  ? -25.267 -28.578 33.138  1    56.56  ? 205 ASP D CA  1 
ATOM   286  C  C   . ASP A 1 35  ? -26.635 -28.37  33.79   1    56.03  ? 205 ASP D C   1 
ATOM   287  O  O   . ASP A 1 35  ? -26.759 -28.572 35      1    60.29  ? 205 ASP D O   1 
ATOM   288  C  CB  . ASP A 1 35  ? -24.103 -27.911 33.85   1    57.45  ? 205 ASP D CB  1 
ATOM   289  C  CG  . ASP A 1 35  ? -23.878 -28.445 35.251  1    64.11  ? 205 ASP D CG  1 
ATOM   290  O  OD1 . ASP A 1 35  ? -23.698 -29.676 35.354  1    69.88  ? 205 ASP D OD1 1 
ATOM   291  O  OD2 . ASP A 1 35  ? -23.945 -27.647 36.221  1    63.49  ? 205 ASP D OD2 1 
ATOM   292  N  N   . ILE A 1 36  ? -27.663 -28.015 33.002  1    50.18  ? 206 ILE D N   1 
ATOM   293  C  CA  . ILE A 1 36  ? -28.988 -27.785 33.566  1    49.49  ? 206 ILE D CA  1 
ATOM   294  C  C   . ILE A 1 36  ? -30.098 -28.315 32.644  1    49.82  ? 206 ILE D C   1 
ATOM   295  O  O   . ILE A 1 36  ? -29.931 -28.439 31.422  1    52.85  ? 206 ILE D O   1 
ATOM   296  C  CB  . ILE A 1 36  ? -29.178 -26.305 33.979  1    53.1   ? 206 ILE D CB  1 
ATOM   297  C  CG1 . ILE A 1 36  ? -29.127 -25.356 32.811  1    50.16  ? 206 ILE D CG1 1 
ATOM   298  C  CG2 . ILE A 1 36  ? -28.2   -25.857 35.075  1    52.04  ? 206 ILE D CG2 1 
ATOM   299  C  CD1 . ILE A 1 36  ? -29.037 -23.909 33.247  1    51.64  ? 206 ILE D CD1 1 
ATOM   300  N  N   . THR A 1 37  ? -31.256 -28.624 33.251  1    46.9   ? 207 THR D N   1 
ATOM   301  C  CA  . THR A 1 37  ? -32.306 -29.43  32.643  1    46.53  ? 207 THR D CA  1 
ATOM   302  C  C   . THR A 1 37  ? -33.679 -28.836 32.924  1    47.36  ? 207 THR D C   1 
ATOM   303  O  O   . THR A 1 37  ? -33.824 -27.975 33.79   1    48.23  ? 207 THR D O   1 
ATOM   304  C  CB  . THR A 1 37  ? -32.249 -30.869 33.167  1    47.33  ? 207 THR D CB  1 
ATOM   305  O  OG1 . THR A 1 37  ? -32.538 -30.888 34.572  1    47.99  ? 207 THR D OG1 1 
ATOM   306  C  CG2 . THR A 1 37  ? -30.991 -31.604 32.73   1    43.59  ? 207 THR D CG2 1 
ATOM   307  N  N   . ASN A 1 38  ? -34.684 -29.333 32.189  1    50.48  ? 208 ASN D N   1 
ATOM   308  C  CA  . ASN A 1 38  ? -36.055 -28.866 32.303  1    51.98  ? 208 ASN D CA  1 
ATOM   309  C  C   . ASN A 1 38  ? -36.564 -29.13  33.72   1    56.16  ? 208 ASN D C   1 
ATOM   310  O  O   . ASN A 1 38  ? -37.353 -28.338 34.245  1    54.98  ? 208 ASN D O   1 
ATOM   311  C  CB  . ASN A 1 38  ? -36.984 -29.539 31.295  1    52.13  ? 208 ASN D CB  1 
ATOM   312  C  CG  . ASN A 1 38  ? -36.712 -29.238 29.832  1    52.59  ? 208 ASN D CG  1 
ATOM   313  O  OD1 . ASN A 1 38  ? -36.422 -28.094 29.435  1    51.89  ? 208 ASN D OD1 1 
ATOM   314  N  ND2 . ASN A 1 38  ? -36.839 -30.269 29.009  1    50.98  ? 208 ASN D ND2 1 
ATOM   315  N  N   . SER A 1 39  ? -36.119 -30.261 34.309  1    57.95  ? 209 SER D N   1 
ATOM   316  C  CA  . SER A 1 39  ? -36.475 -30.693 35.659  1    55.41  ? 209 SER D CA  1 
ATOM   317  C  C   . SER A 1 39  ? -35.917 -29.707 36.692  1    53.39  ? 209 SER D C   1 
ATOM   318  O  O   . SER A 1 39  ? -36.591 -29.357 37.664  1    53.33  ? 209 SER D O   1 
ATOM   319  C  CB  . SER A 1 39  ? -35.994 -32.115 35.924  1    55.34  ? 209 SER D CB  1 
ATOM   320  O  OG  . SER A 1 39  ? -35.969 -32.425 37.316  1    54.31  ? 209 SER D OG  1 
ATOM   321  N  N   . MET A 1 40  ? -34.67  -29.274 36.489  1    49.37  ? 210 MET D N   1 
ATOM   322  C  CA  . MET A 1 40  ? -34.063 -28.326 37.411  1    48.86  ? 210 MET D CA  1 
ATOM   323  C  C   . MET A 1 40  ? -34.822 -27.012 37.359  1    46.28  ? 210 MET D C   1 
ATOM   324  O  O   . MET A 1 40  ? -34.962 -26.338 38.377  1    47.72  ? 210 MET D O   1 
ATOM   325  C  CB  . MET A 1 40  ? -32.607 -28.006 37.056  1    45.67  ? 210 MET D CB  1 
ATOM   326  C  CG  . MET A 1 40  ? -31.727 -29.2   37.208  1    46.61  ? 210 MET D CG  1 
ATOM   327  S  SD  . MET A 1 40  ? -30.065 -28.67  36.794  1    47.46  ? 210 MET D SD  1 
ATOM   328  C  CE  . MET A 1 40  ? -29.264 -30.281 36.817  1    43.23  ? 210 MET D CE  1 
ATOM   329  N  N   . ARG A 1 41  ? -35.282 -26.672 36.156  1    42.6   ? 211 ARG D N   1 
ATOM   330  C  CA  . ARG A 1 41  ? -35.886 -25.378 35.906  1    43.22  ? 211 ARG D CA  1 
ATOM   331  C  C   . ARG A 1 41  ? -37.29  -25.397 36.501  1    43.04  ? 211 ARG D C   1 
ATOM   332  O  O   . ARG A 1 41  ? -37.722 -24.39  37.063  1    44.45  ? 211 ARG D O   1 
ATOM   333  C  CB  . ARG A 1 41  ? -35.865 -25.047 34.407  1    42.09  ? 211 ARG D CB  1 
ATOM   334  C  CG  . ARG A 1 41  ? -36.93  -24.045 33.992  1    41.96  ? 211 ARG D CG  1 
ATOM   335  C  CD  . ARG A 1 41  ? -36.977 -23.776 32.503  1    46.61  ? 211 ARG D CD  1 
ATOM   336  N  NE  . ARG A 1 41  ? -37.882 -22.669 32.171  1    46.8   ? 211 ARG D NE  1 
ATOM   337  C  CZ  . ARG A 1 41  ? -39.175 -22.671 32.428  1    42.24  ? 211 ARG D CZ  1 
ATOM   338  N  NH1 . ARG A 1 41  ? -39.718 -23.723 33.019  1    41.66  ? 211 ARG D NH1 1 
ATOM   339  N  NH2 . ARG A 1 41  ? -39.902 -21.613 32.115  1    36.35  ? 211 ARG D NH2 1 
ATOM   340  N  N   . ALA A 1 42  ? -37.982 -26.532 36.34   1    42.17  ? 212 ALA D N   1 
ATOM   341  C  CA  . ALA A 1 42  ? -39.251 -26.792 37.002  1    46.39  ? 212 ALA D CA  1 
ATOM   342  C  C   . ALA A 1 42  ? -39.127 -26.517 38.506  1    50.59  ? 212 ALA D C   1 
ATOM   343  O  O   . ALA A 1 42  ? -39.988 -25.857 39.092  1    52.6   ? 212 ALA D O   1 
ATOM   344  C  CB  . ALA A 1 42  ? -39.696 -28.217 36.748  1    44.08  ? 212 ALA D CB  1 
ATOM   345  N  N   . ILE A 1 43  ? -38.063 -27.029 39.141  1    49.87  ? 213 ILE D N   1 
ATOM   346  C  CA  . ILE A 1 43  ? -37.874 -26.824 40.57   1    47.81  ? 213 ILE D CA  1 
ATOM   347  C  C   . ILE A 1 43  ? -37.715 -25.334 40.884  1    47.58  ? 213 ILE D C   1 
ATOM   348  O  O   . ILE A 1 43  ? -38.248 -24.836 41.875  1    46.71  ? 213 ILE D O   1 
ATOM   349  C  CB  . ILE A 1 43  ? -36.692 -27.675 41.05   1    45.4   ? 213 ILE D CB  1 
ATOM   350  C  CG1 . ILE A 1 43  ? -37.08  -29.175 41.006  1    44.33  ? 213 ILE D CG1 1 
ATOM   351  C  CG2 . ILE A 1 43  ? -36.22  -27.22  42.429  1    41.28  ? 213 ILE D CG2 1 
ATOM   352  C  CD1 . ILE A 1 43  ? -35.902 -30.11  40.86   1    41.61  ? 213 ILE D CD1 1 
ATOM   353  N  N   . LEU A 1 44  ? -36.985 -24.642 40.01   1    45.24  ? 214 LEU D N   1 
ATOM   354  C  CA  . LEU A 1 44  ? -36.714 -23.234 40.184  1    46     ? 214 LEU D CA  1 
ATOM   355  C  C   . LEU A 1 44  ? -38.026 -22.453 40.161  1    48.32  ? 214 LEU D C   1 
ATOM   356  O  O   . LEU A 1 44  ? -38.295 -21.689 41.085  1    50.66  ? 214 LEU D O   1 
ATOM   357  C  CB  . LEU A 1 44  ? -35.752 -22.748 39.107  1    43.11  ? 214 LEU D CB  1 
ATOM   358  C  CG  . LEU A 1 44  ? -35.342 -21.275 39.23   1    41.33  ? 214 LEU D CG  1 
ATOM   359  C  CD1 . LEU A 1 44  ? -34.518 -21.057 40.513  1    38.72  ? 214 LEU D CD1 1 
ATOM   360  C  CD2 . LEU A 1 44  ? -34.568 -20.825 37.981  1    35.85  ? 214 LEU D CD2 1 
ATOM   361  N  N   . VAL A 1 45  ? -38.84  -22.665 39.117  1    46.5   ? 215 VAL D N   1 
ATOM   362  C  CA  . VAL A 1 45  ? -40.071 -21.909 38.914  1    42.89  ? 215 VAL D CA  1 
ATOM   363  C  C   . VAL A 1 45  ? -41.038 -22.161 40.066  1    41.51  ? 215 VAL D C   1 
ATOM   364  O  O   . VAL A 1 45  ? -41.728 -21.24  40.515  1    39.37  ? 215 VAL D O   1 
ATOM   365  C  CB  . VAL A 1 45  ? -40.725 -22.218 37.555  1    40.46  ? 215 VAL D CB  1 
ATOM   366  C  CG1 . VAL A 1 45  ? -42.087 -21.544 37.396  1    37.31  ? 215 VAL D CG1 1 
ATOM   367  C  CG2 . VAL A 1 45  ? -39.8   -21.833 36.412  1    35.62  ? 215 VAL D CG2 1 
ATOM   368  N  N   . ASP A 1 46  ? -41.082 -23.425 40.507  1    43.77  ? 216 ASP D N   1 
ATOM   369  C  CA  . ASP A 1 46  ? -42.002 -23.868 41.544  1    45.17  ? 216 ASP D CA  1 
ATOM   370  C  C   . ASP A 1 46  ? -41.696 -23.124 42.834  1    48.25  ? 216 ASP D C   1 
ATOM   371  O  O   . ASP A 1 46  ? -42.616 -22.701 43.541  1    52.64  ? 216 ASP D O   1 
ATOM   372  C  CB  . ASP A 1 46  ? -41.855 -25.342 41.848  1    44.62  ? 216 ASP D CB  1 
ATOM   373  C  CG  . ASP A 1 46  ? -42.966 -25.875 42.728  1    48.62  ? 216 ASP D CG  1 
ATOM   374  O  OD1 . ASP A 1 46  ? -44.071 -26.095 42.194  1    50.88  ? 216 ASP D OD1 1 
ATOM   375  O  OD2 . ASP A 1 46  ? -42.731 -25.994 43.936  1    50.4   ? 216 ASP D OD2 1 
ATOM   376  N  N   . TRP A 1 47  ? -40.387 -22.994 43.103  1    46.86  ? 217 TRP D N   1 
ATOM   377  C  CA  . TRP A 1 47  ? -39.83  -22.241 44.211  1    46.38  ? 217 TRP D CA  1 
ATOM   378  C  C   . TRP A 1 47  ? -40.227 -20.758 44.125  1    45.63  ? 217 TRP D C   1 
ATOM   379  O  O   . TRP A 1 47  ? -40.662 -20.178 45.114  1    47.3   ? 217 TRP D O   1 
ATOM   380  C  CB  . TRP A 1 47  ? -38.308 -22.465 44.291  1    44.91  ? 217 TRP D CB  1 
ATOM   381  C  CG  . TRP A 1 47  ? -37.651 -21.604 45.34   1    50.35  ? 217 TRP D CG  1 
ATOM   382  C  CD1 . TRP A 1 47  ? -37.781 -21.719 46.7    1    48.84  ? 217 TRP D CD1 1 
ATOM   383  C  CD2 . TRP A 1 47  ? -36.788 -20.465 45.116  1    45.02  ? 217 TRP D CD2 1 
ATOM   384  N  NE1 . TRP A 1 47  ? -37.069 -20.732 47.331  1    46.89  ? 217 TRP D NE1 1 
ATOM   385  C  CE2 . TRP A 1 47  ? -36.45  -19.952 46.386  1    45.2   ? 217 TRP D CE2 1 
ATOM   386  C  CE3 . TRP A 1 47  ? -36.273 -19.844 43.98   1    43.07  ? 217 TRP D CE3 1 
ATOM   387  C  CZ2 . TRP A 1 47  ? -35.611 -18.854 46.538  1    44.68  ? 217 TRP D CZ2 1 
ATOM   388  C  CZ3 . TRP A 1 47  ? -35.44  -18.756 44.131  1    43.28  ? 217 TRP D CZ3 1 
ATOM   389  C  CH2 . TRP A 1 47  ? -35.117 -18.268 45.391  1    43.88  ? 217 TRP D CH2 1 
ATOM   390  N  N   . LEU A 1 48  ? -40.118 -20.156 42.938  1    42.99  ? 218 LEU D N   1 
ATOM   391  C  CA  . LEU A 1 48  ? -40.501 -18.772 42.705  1    42.38  ? 218 LEU D CA  1 
ATOM   392  C  C   . LEU A 1 48  ? -41.994 -18.568 42.988  1    46.31  ? 218 LEU D C   1 
ATOM   393  O  O   . LEU A 1 48  ? -42.383 -17.532 43.53   1    44.2   ? 218 LEU D O   1 
ATOM   394  C  CB  . LEU A 1 48  ? -40.086 -18.362 41.292  1    40.75  ? 218 LEU D CB  1 
ATOM   395  C  CG  . LEU A 1 48  ? -38.577 -18.195 41.073  1    41.77  ? 218 LEU D CG  1 
ATOM   396  C  CD1 . LEU A 1 48  ? -38.234 -17.774 39.662  1    43.77  ? 218 LEU D CD1 1 
ATOM   397  C  CD2 . LEU A 1 48  ? -38.027 -17.157 42.028  1    42.81  ? 218 LEU D CD2 1 
ATOM   398  N  N   . VAL A 1 49  ? -42.819 -19.585 42.696  1    47.55  ? 219 VAL D N   1 
ATOM   399  C  CA  . VAL A 1 49  ? -44.241 -19.554 43.022  1    50.13  ? 219 VAL D CA  1 
ATOM   400  C  C   . VAL A 1 49  ? -44.44  -19.389 44.534  1    52.8   ? 219 VAL D C   1 
ATOM   401  O  O   . VAL A 1 49  ? -45.242 -18.557 44.966  1    52.72  ? 219 VAL D O   1 
ATOM   402  C  CB  . VAL A 1 49  ? -44.978 -20.791 42.457  1    50.22  ? 219 VAL D CB  1 
ATOM   403  C  CG1 . VAL A 1 49  ? -46.374 -20.985 43.052  1    46.92  ? 219 VAL D CG1 1 
ATOM   404  C  CG2 . VAL A 1 49  ? -45.032 -20.763 40.932  1    47.16  ? 219 VAL D CG2 1 
ATOM   405  N  N   . GLU A 1 50  ? -43.729 -20.213 45.321  1    55.09  ? 220 GLU D N   1 
ATOM   406  C  CA  . GLU A 1 50  ? -43.751 -20.141 46.78   1    57.62  ? 220 GLU D CA  1 
ATOM   407  C  C   . GLU A 1 50  ? -43.306 -18.763 47.266  1    51.53  ? 220 GLU D C   1 
ATOM   408  O  O   . GLU A 1 50  ? -43.985 -18.148 48.079  1    51.52  ? 220 GLU D O   1 
ATOM   409  C  CB  . GLU A 1 50  ? -42.793 -21.111 47.473  1    58.32  ? 220 GLU D CB  1 
ATOM   410  C  CG  . GLU A 1 50  ? -43.31  -22.542 47.523  1    64.72  ? 220 GLU D CG  1 
ATOM   411  C  CD  . GLU A 1 50  ? -42.41  -23.493 48.287  1    71.09  ? 220 GLU D CD  1 
ATOM   412  O  OE1 . GLU A 1 50  ? -42.957 -24.231 49.138  1    79.88  ? 220 GLU D OE1 1 
ATOM   413  O  OE2 . GLU A 1 50  ? -41.179 -23.504 48.033  1    71.64  ? 220 GLU D OE2 1 
ATOM   414  N  N   . VAL A 1 51  ? -42.146 -18.316 46.776  1    46.72  ? 221 VAL D N   1 
ATOM   415  C  CA  . VAL A 1 51  ? -41.598 -17.014 47.109  1    44.9   ? 221 VAL D CA  1 
ATOM   416  C  C   . VAL A 1 51  ? -42.671 -15.963 46.842  1    44.64  ? 221 VAL D C   1 
ATOM   417  O  O   . VAL A 1 51  ? -42.908 -15.074 47.664  1    42.8   ? 221 VAL D O   1 
ATOM   418  C  CB  . VAL A 1 51  ? -40.302 -16.733 46.325  1    39.12  ? 221 VAL D CB  1 
ATOM   419  C  CG1 . VAL A 1 51  ? -39.903 -15.27  46.445  1    34.04  ? 221 VAL D CG1 1 
ATOM   420  C  CG2 . VAL A 1 51  ? -39.178 -17.65  46.797  1    38.2   ? 221 VAL D CG2 1 
ATOM   421  N  N   . GLY A 1 52  ? -43.333 -16.12  45.694  1    42.82  ? 222 GLY D N   1 
ATOM   422  C  CA  . GLY A 1 52  ? -44.434 -15.262 45.299  1    43.47  ? 222 GLY D CA  1 
ATOM   423  C  C   . GLY A 1 52  ? -45.558 -15.215 46.339  1    48.44  ? 222 GLY D C   1 
ATOM   424  O  O   . GLY A 1 52  ? -46.077 -14.131 46.616  1    51.55  ? 222 GLY D O   1 
ATOM   425  N  N   . GLU A 1 53  ? -45.94  -16.378 46.887  1    47.71  ? 223 GLU D N   1 
ATOM   426  C  CA  . GLU A 1 53  ? -47.015 -16.473 47.865  1    50.11  ? 223 GLU D CA  1 
ATOM   427  C  C   . GLU A 1 53  ? -46.555 -15.964 49.23   1    50.66  ? 223 GLU D C   1 
ATOM   428  O  O   . GLU A 1 53  ? -47.301 -15.27  49.899  1    52.96  ? 223 GLU D O   1 
ATOM   429  C  CB  . GLU A 1 53  ? -47.614 -17.878 47.911  1    52.83  ? 223 GLU D CB  1 
ATOM   430  C  CG  . GLU A 1 53  ? -48.594 -18.113 46.762  1    59.71  ? 223 GLU D CG  1 
ATOM   431  C  CD  . GLU A 1 53  ? -50.057 -17.699 46.974  1    72.47  ? 223 GLU D CD  1 
ATOM   432  O  OE1 . GLU A 1 53  ? -50.455 -16.703 46.271  1    65.73  ? 223 GLU D OE1 1 
ATOM   433  O  OE2 . GLU A 1 53  ? -50.809 -18.383 47.781  1    63.12  ? 223 GLU D OE2 1 
ATOM   434  N  N   . GLU A 1 54  ? -45.312 -16.254 49.63   1    52.98  ? 224 GLU D N   1 
ATOM   435  C  CA  . GLU A 1 54  ? -44.791 -15.795 50.912  1    55.43  ? 224 GLU D CA  1 
ATOM   436  C  C   . GLU A 1 54  ? -44.58  -14.274 50.976  1    53.22  ? 224 GLU D C   1 
ATOM   437  O  O   . GLU A 1 54  ? -44.609 -13.69  52.055  1    54.68  ? 224 GLU D O   1 
ATOM   438  C  CB  . GLU A 1 54  ? -43.514 -16.533 51.313  1    58.52  ? 224 GLU D CB  1 
ATOM   439  C  CG  . GLU A 1 54  ? -42.754 -15.756 52.381  1    70.05  ? 224 GLU D CG  1 
ATOM   440  C  CD  . GLU A 1 54  ? -41.72  -16.449 53.241  1    86.41  ? 224 GLU D CD  1 
ATOM   441  O  OE1 . GLU A 1 54  ? -42.091 -16.684 54.418  1    99.08  ? 224 GLU D OE1 1 
ATOM   442  O  OE2 . GLU A 1 54  ? -40.574 -16.699 52.769  1    93.93  ? 224 GLU D OE2 1 
ATOM   443  N  N   . TYR A 1 55  ? -44.31  -13.624 49.844  1    50.37  ? 225 TYR D N   1 
ATOM   444  C  CA  . TYR A 1 55  ? -44.053 -12.191 49.828  1    52.2   ? 225 TYR D CA  1 
ATOM   445  C  C   . TYR A 1 55  ? -45.276 -11.449 49.295  1    54.09  ? 225 TYR D C   1 
ATOM   446  O  O   . TYR A 1 55  ? -45.208 -10.253 49.01   1    56.1   ? 225 TYR D O   1 
ATOM   447  C  CB  . TYR A 1 55  ? -42.733 -11.872 49.106  1    50.26  ? 225 TYR D CB  1 
ATOM   448  C  CG  . TYR A 1 55  ? -41.547 -12.153 50.013  1    53.06  ? 225 TYR D CG  1 
ATOM   449  C  CD1 . TYR A 1 55  ? -41.224 -11.301 51.065  1    54.87  ? 225 TYR D CD1 1 
ATOM   450  C  CD2 . TYR A 1 55  ? -40.825 -13.334 49.903  1    58.13  ? 225 TYR D CD2 1 
ATOM   451  C  CE1 . TYR A 1 55  ? -40.189 -11.605 51.94   1    56.33  ? 225 TYR D CE1 1 
ATOM   452  C  CE2 . TYR A 1 55  ? -39.791 -13.646 50.775  1    55.96  ? 225 TYR D CE2 1 
ATOM   453  C  CZ  . TYR A 1 55  ? -39.464 -12.775 51.792  1    53.52  ? 225 TYR D CZ  1 
ATOM   454  O  OH  . TYR A 1 55  ? -38.427 -13.074 52.615  1    55.48  ? 225 TYR D OH  1 
ATOM   455  N  N   . LYS A 1 56  ? -46.379 -12.194 49.159  1    55.55  ? 226 LYS D N   1 
ATOM   456  C  CA  . LYS A 1 56  ? -47.64  -11.726 48.599  1    54.19  ? 226 LYS D CA  1 
ATOM   457  C  C   . LYS A 1 56  ? -47.414 -10.899 47.339  1    48.96  ? 226 LYS D C   1 
ATOM   458  O  O   . LYS A 1 56  ? -47.99  -9.829  47.203  1    54.08  ? 226 LYS D O   1 
ATOM   459  C  CB  . LYS A 1 56  ? -48.489 -11.026 49.669  1    60.19  ? 226 LYS D CB  1 
ATOM   460  C  CG  . LYS A 1 56  ? -49.44  -11.92  50.468  1    68.49  ? 226 LYS D CG  1 
ATOM   461  C  CD  . LYS A 1 56  ? -48.819 -13.005 51.347  1    77.05  ? 226 LYS D CD  1 
ATOM   462  C  CE  . LYS A 1 56  ? -49.857 -13.945 51.899  1    75.21  ? 226 LYS D CE  1 
ATOM   463  N  NZ  . LYS A 1 56  ? -50.905 -13.144 52.556  1    69.72  ? 226 LYS D NZ  1 
ATOM   464  N  N   . LEU A 1 57  ? -46.59  -11.406 46.422  1    45.24  ? 227 LEU D N   1 
ATOM   465  C  CA  . LEU A 1 57  ? -46.317 -10.702 45.177  1    45.52  ? 227 LEU D CA  1 
ATOM   466  C  C   . LEU A 1 57  ? -47.478 -10.887 44.205  1    46.96  ? 227 LEU D C   1 
ATOM   467  O  O   . LEU A 1 57  ? -48.271 -11.806 44.354  1    57.51  ? 227 LEU D O   1 
ATOM   468  C  CB  . LEU A 1 57  ? -45.019 -11.219 44.552  1    42.58  ? 227 LEU D CB  1 
ATOM   469  C  CG  . LEU A 1 57  ? -43.778 -11.188 45.45   1    40.62  ? 227 LEU D CG  1 
ATOM   470  C  CD1 . LEU A 1 57  ? -42.604 -11.68  44.646  1    35.92  ? 227 LEU D CD1 1 
ATOM   471  C  CD2 . LEU A 1 57  ? -43.531 -9.798  46.017  1    38.7   ? 227 LEU D CD2 1 
ATOM   472  N  N   . GLN A 1 58  ? -47.545 -10.023 43.188  1    45.87  ? 228 GLN D N   1 
ATOM   473  C  CA  . GLN A 1 58  ? -48.479 -10.157 42.079  1    45.41  ? 228 GLN D CA  1 
ATOM   474  C  C   . GLN A 1 58  ? -48.116 -11.352 41.189  1    46.8   ? 228 GLN D C   1 
ATOM   475  O  O   . GLN A 1 58  ? -46.947 -11.628 40.936  1    49.52  ? 228 GLN D O   1 
ATOM   476  C  CB  . GLN A 1 58  ? -48.394 -8.916  41.195  1    41.88  ? 228 GLN D CB  1 
ATOM   477  C  CG  . GLN A 1 58  ? -48.797 -7.631  41.894  1    41.75  ? 228 GLN D CG  1 
ATOM   478  C  CD  . GLN A 1 58  ? -50.272 -7.651  42.176  1    44.37  ? 228 GLN D CD  1 
ATOM   479  O  OE1 . GLN A 1 58  ? -51.096 -7.703  41.253  1    49.98  ? 228 GLN D OE1 1 
ATOM   480  N  NE2 . GLN A 1 58  ? -50.595 -7.671  43.456  1    43.08  ? 228 GLN D NE2 1 
ATOM   481  N  N   . ASN A 1 59  ? -49.134 -12.006 40.634  1    47.05  ? 229 ASN D N   1 
ATOM   482  C  CA  . ASN A 1 59  ? -48.897 -13.081 39.688  1    45.88  ? 229 ASN D CA  1 
ATOM   483  C  C   . ASN A 1 59  ? -48.077 -12.592 38.504  1    44.35  ? 229 ASN D C   1 
ATOM   484  O  O   . ASN A 1 59  ? -47.208 -13.334 38.032  1    43.55  ? 229 ASN D O   1 
ATOM   485  C  CB  . ASN A 1 59  ? -50.189 -13.748 39.242  1    46.67  ? 229 ASN D CB  1 
ATOM   486  C  CG  . ASN A 1 59  ? -50.861 -14.427 40.402  1    53.15  ? 229 ASN D CG  1 
ATOM   487  O  OD1 . ASN A 1 59  ? -50.193 -14.817 41.374  1    53.28  ? 229 ASN D OD1 1 
ATOM   488  N  ND2 . ASN A 1 59  ? -52.177 -14.564 40.312  1    59.48  ? 229 ASN D ND2 1 
ATOM   489  N  N   . GLU A 1 60  ? -48.393 -11.377 38.018  1    43.56  ? 230 GLU D N   1 
ATOM   490  C  CA  . GLU A 1 60  ? -47.669 -10.754 36.913  1    42.61  ? 230 GLU D CA  1 
ATOM   491  C  C   . GLU A 1 60  ? -46.15  -10.722 37.168  1    43.46  ? 230 GLU D C   1 
ATOM   492  O  O   . GLU A 1 60  ? -45.356 -10.831 36.234  1    45.24  ? 230 GLU D O   1 
ATOM   493  C  CB  . GLU A 1 60  ? -48.273 -9.371  36.683  1    41.3   ? 230 GLU D CB  1 
ATOM   494  C  CG  . GLU A 1 60  ? -47.536 -8.528  35.643  1    45.09  ? 230 GLU D CG  1 
ATOM   495  C  CD  . GLU A 1 60  ? -47.566 -9.042  34.214  1    46.06  ? 230 GLU D CD  1 
ATOM   496  O  OE1 . GLU A 1 60  ? -48.222 -10.067 33.98   1    48.96  ? 230 GLU D OE1 1 
ATOM   497  O  OE2 . GLU A 1 60  ? -46.943 -8.423  33.34   1    46.6   ? 230 GLU D OE2 1 
ATOM   498  N  N   . THR A 1 61  ? -45.734 -10.548 38.433  1    42.35  ? 231 THR D N   1 
ATOM   499  C  CA  . THR A 1 61  ? -44.326 -10.455 38.797  1    42.61  ? 231 THR D CA  1 
ATOM   500  C  C   . THR A 1 61  ? -43.64  -11.805 38.558  1    42.23  ? 231 THR D C   1 
ATOM   501  O  O   . THR A 1 61  ? -42.553 -11.846 37.976  1    40.56  ? 231 THR D O   1 
ATOM   502  C  CB  . THR A 1 61  ? -44.162 -9.96   40.241  1    41.68  ? 231 THR D CB  1 
ATOM   503  O  OG1 . THR A 1 61  ? -44.787 -8.686  40.332  1    41.59  ? 231 THR D OG1 1 
ATOM   504  C  CG2 . THR A 1 61  ? -42.712 -9.747  40.644  1    38.84  ? 231 THR D CG2 1 
ATOM   505  N  N   . LEU A 1 62  ? -44.274 -12.893 39.032  1    42.41  ? 232 LEU D N   1 
ATOM   506  C  CA  . LEU A 1 62  ? -43.824 -14.261 38.811  1    41.73  ? 232 LEU D CA  1 
ATOM   507  C  C   . LEU A 1 62  ? -43.676 -14.561 37.321  1    41.54  ? 232 LEU D C   1 
ATOM   508  O  O   . LEU A 1 62  ? -42.699 -15.199 36.922  1    42.43  ? 232 LEU D O   1 
ATOM   509  C  CB  . LEU A 1 62  ? -44.749 -15.254 39.513  1    42.87  ? 232 LEU D CB  1 
ATOM   510  C  CG  . LEU A 1 62  ? -44.652 -16.71  39.049  1    44.39  ? 232 LEU D CG  1 
ATOM   511  C  CD1 . LEU A 1 62  ? -43.284 -17.335 39.295  1    42.04  ? 232 LEU D CD1 1 
ATOM   512  C  CD2 . LEU A 1 62  ? -45.751 -17.544 39.671  1    44.12  ? 232 LEU D CD2 1 
ATOM   513  N  N   . HIS A 1 63  ? -44.643 -14.114 36.502  1    43.8   ? 233 HIS D N   1 
ATOM   514  C  CA  . HIS A 1 63  ? -44.587 -14.33  35.054  1    42.23  ? 233 HIS D CA  1 
ATOM   515  C  C   . HIS A 1 63  ? -43.433 -13.546 34.417  1    43.1   ? 233 HIS D C   1 
ATOM   516  O  O   . HIS A 1 63  ? -42.785 -14.031 33.495  1    48.54  ? 233 HIS D O   1 
ATOM   517  C  CB  . HIS A 1 63  ? -45.898 -13.926 34.364  1    40.03  ? 233 HIS D CB  1 
ATOM   518  C  CG  . HIS A 1 63  ? -46.976 -14.948 34.306  1    43.02  ? 233 HIS D CG  1 
ATOM   519  N  ND1 . HIS A 1 63  ? -47.836 -15.211 35.361  1    43.06  ? 233 HIS D ND1 1 
ATOM   520  C  CD2 . HIS A 1 63  ? -47.341 -15.741 33.297  1    41.24  ? 233 HIS D CD2 1 
ATOM   521  C  CE1 . HIS A 1 63  ? -48.698 -16.135 34.995  1    41.03  ? 233 HIS D CE1 1 
ATOM   522  N  NE2 . HIS A 1 63  ? -48.408 -16.469 33.755  1    42.8   ? 233 HIS D NE2 1 
ATOM   523  N  N   . LEU A 1 64  ? -43.209 -12.303 34.862  1    39.41  ? 234 LEU D N   1 
ATOM   524  C  CA  . LEU A 1 64  ? -42.084 -11.539 34.367  1    37.41  ? 234 LEU D CA  1 
ATOM   525  C  C   . LEU A 1 64  ? -40.792 -12.273 34.731  1    41.27  ? 234 LEU D C   1 
ATOM   526  O  O   . LEU A 1 64  ? -39.949 -12.501 33.86   1    42.19  ? 234 LEU D O   1 
ATOM   527  C  CB  . LEU A 1 64  ? -42.146 -10.125 34.931  1    34.97  ? 234 LEU D CB  1 
ATOM   528  C  CG  . LEU A 1 64  ? -43.208 -9.234  34.279  1    37.26  ? 234 LEU D CG  1 
ATOM   529  C  CD1 . LEU A 1 64  ? -43.463 -7.965  35.095  1    34.81  ? 234 LEU D CD1 1 
ATOM   530  C  CD2 . LEU A 1 64  ? -42.809 -8.893  32.847  1    32.67  ? 234 LEU D CD2 1 
ATOM   531  N  N   . ALA A 1 65  ? -40.676 -12.715 35.996  1    38.22  ? 235 ALA D N   1 
ATOM   532  C  CA  . ALA A 1 65  ? -39.446 -13.334 36.457  1    36.73  ? 235 ALA D CA  1 
ATOM   533  C  C   . ALA A 1 65  ? -39.039 -14.492 35.552  1    37.49  ? 235 ALA D C   1 
ATOM   534  O  O   . ALA A 1 65  ? -37.86  -14.561 35.215  1    37.39  ? 235 ALA D O   1 
ATOM   535  C  CB  . ALA A 1 65  ? -39.543 -13.73  37.913  1    38.04  ? 235 ALA D CB  1 
ATOM   536  N  N   . VAL A 1 66  ? -40.003 -15.357 35.144  1    36.04  ? 236 VAL D N   1 
ATOM   537  C  CA  . VAL A 1 66  ? -39.731 -16.535 34.322  1    36.58  ? 236 VAL D CA  1 
ATOM   538  C  C   . VAL A 1 66  ? -39.298 -16.103 32.908  1    40.23  ? 236 VAL D C   1 
ATOM   539  O  O   . VAL A 1 66  ? -38.404 -16.71  32.28   1    42.82  ? 236 VAL D O   1 
ATOM   540  C  CB  . VAL A 1 66  ? -40.955 -17.466 34.257  1    37.5   ? 236 VAL D CB  1 
ATOM   541  C  CG1 . VAL A 1 66  ? -40.746 -18.598 33.27   1    34.87  ? 236 VAL D CG1 1 
ATOM   542  C  CG2 . VAL A 1 66  ? -41.36  -18.022 35.613  1    39.62  ? 236 VAL D CG2 1 
ATOM   543  N  N   . ASN A 1 67  ? -39.954 -15.061 32.378  1    33.47  ? 237 ASN D N   1 
ATOM   544  C  CA  . ASN A 1 67  ? -39.511 -14.502 31.114  1    33.61  ? 237 ASN D CA  1 
ATOM   545  C  C   . ASN A 1 67  ? -38.027 -14.141 31.199  1    35.27  ? 237 ASN D C   1 
ATOM   546  O  O   . ASN A 1 67  ? -37.277 -14.402 30.263  1    39.91  ? 237 ASN D O   1 
ATOM   547  C  CB  . ASN A 1 67  ? -40.314 -13.277 30.702  1    32.58  ? 237 ASN D CB  1 
ATOM   548  C  CG  . ASN A 1 67  ? -39.888 -12.787 29.334  1    38.6   ? 237 ASN D CG  1 
ATOM   549  O  OD1 . ASN A 1 67  ? -39.163 -11.79  29.225  1    43.55  ? 237 ASN D OD1 1 
ATOM   550  N  ND2 . ASN A 1 67  ? -40.28  -13.485 28.27   1    40.22  ? 237 ASN D ND2 1 
ATOM   551  N  N   . TYR A 1 68  ? -37.606 -13.518 32.312  1    34.17  ? 238 TYR D N   1 
ATOM   552  C  CA  . TYR A 1 68  ? -36.261 -12.975 32.419  1    35.91  ? 238 TYR D CA  1 
ATOM   553  C  C   . TYR A 1 68  ? -35.26  -14.129 32.423  1    41.27  ? 238 TYR D C   1 
ATOM   554  O  O   . TYR A 1 68  ? -34.26  -14.111 31.691  1    41.86  ? 238 TYR D O   1 
ATOM   555  C  CB  . TYR A 1 68  ? -36.158 -12.091 33.666  1    34.49  ? 238 TYR D CB  1 
ATOM   556  C  CG  . TYR A 1 68  ? -37.051 -10.856 33.65   1    35.79  ? 238 TYR D CG  1 
ATOM   557  C  CD1 . TYR A 1 68  ? -37.716 -10.445 32.49   1    33.93  ? 238 TYR D CD1 1 
ATOM   558  C  CD2 . TYR A 1 68  ? -37.242 -10.099 34.805  1    34.44  ? 238 TYR D CD2 1 
ATOM   559  C  CE1 . TYR A 1 68  ? -38.526 -9.314  32.472  1    33.98  ? 238 TYR D CE1 1 
ATOM   560  C  CE2 . TYR A 1 68  ? -38.068 -8.985  34.808  1    34.04  ? 238 TYR D CE2 1 
ATOM   561  C  CZ  . TYR A 1 68  ? -38.698 -8.583  33.635  1    36.42  ? 238 TYR D CZ  1 
ATOM   562  O  OH  . TYR A 1 68  ? -39.495 -7.47   33.609  1    40.92  ? 238 TYR D OH  1 
ATOM   563  N  N   . ILE A 1 69  ? -35.591 -15.154 33.228  1    43.6   ? 239 ILE D N   1 
ATOM   564  C  CA  . ILE A 1 69  ? -34.798 -16.364 33.408  1    41.01  ? 239 ILE D CA  1 
ATOM   565  C  C   . ILE A 1 69  ? -34.603 -17.068 32.067  1    42.92  ? 239 ILE D C   1 
ATOM   566  O  O   . ILE A 1 69  ? -33.481 -17.407 31.7    1    40.82  ? 239 ILE D O   1 
ATOM   567  C  CB  . ILE A 1 69  ? -35.433 -17.295 34.458  1    38.86  ? 239 ILE D CB  1 
ATOM   568  C  CG1 . ILE A 1 69  ? -35.481 -16.608 35.854  1    35.81  ? 239 ILE D CG1 1 
ATOM   569  C  CG2 . ILE A 1 69  ? -34.702 -18.642 34.481  1    35.15  ? 239 ILE D CG2 1 
ATOM   570  C  CD1 . ILE A 1 69  ? -36.346 -17.297 36.897  1    32.4   ? 239 ILE D CD1 1 
ATOM   571  N  N   . ASP A 1 70  ? -35.701 -17.264 31.329  1    44.38  ? 240 ASP D N   1 
ATOM   572  C  CA  . ASP A 1 70  ? -35.647 -18.006 30.079  1    43.59  ? 240 ASP D CA  1 
ATOM   573  C  C   . ASP A 1 70  ? -34.844 -17.249 29.032  1    40.83  ? 240 ASP D C   1 
ATOM   574  O  O   . ASP A 1 70  ? -34.211 -17.897 28.203  1    42.51  ? 240 ASP D O   1 
ATOM   575  C  CB  . ASP A 1 70  ? -37.039 -18.332 29.571  1    42.6   ? 240 ASP D CB  1 
ATOM   576  C  CG  . ASP A 1 70  ? -37.727 -19.452 30.331  1    45.43  ? 240 ASP D CG  1 
ATOM   577  O  OD1 . ASP A 1 70  ? -36.991 -20.292 30.942  1    41.02  ? 240 ASP D OD1 1 
ATOM   578  O  OD2 . ASP A 1 70  ? -38.988 -19.454 30.328  1    44.68  ? 240 ASP D OD2 1 
ATOM   579  N  N   . ARG A 1 71  ? -34.883 -15.902 29.054  1    37.48  ? 241 ARG D N   1 
ATOM   580  C  CA  . ARG A 1 71  ? -34.119 -15.144 28.064  1    39.67  ? 241 ARG D CA  1 
ATOM   581  C  C   . ARG A 1 71  ? -32.639 -15.155 28.437  1    40.06  ? 241 ARG D C   1 
ATOM   582  O  O   . ARG A 1 71  ? -31.774 -15.324 27.573  1    40.42  ? 241 ARG D O   1 
ATOM   583  C  CB  . ARG A 1 71  ? -34.625 -13.711 27.876  1    38.99  ? 241 ARG D CB  1 
ATOM   584  C  CG  . ARG A 1 71  ? -35.84  -13.612 26.966  1    40.21  ? 241 ARG D CG  1 
ATOM   585  C  CD  . ARG A 1 71  ? -36.846 -12.554 27.39   1    39.86  ? 241 ARG D CD  1 
ATOM   586  N  NE  . ARG A 1 71  ? -36.446 -11.262 26.835  1    42.45  ? 241 ARG D NE  1 
ATOM   587  C  CZ  . ARG A 1 71  ? -36.472 -10.104 27.493  1    43.54  ? 241 ARG D CZ  1 
ATOM   588  N  NH1 . ARG A 1 71  ? -37.31  -9.914  28.516  1    37.77  ? 241 ARG D NH1 1 
ATOM   589  N  NH2 . ARG A 1 71  ? -35.714 -9.116  27.041  1    36.66  ? 241 ARG D NH2 1 
ATOM   590  N  N   . PHE A 1 72  ? -32.371 -15.019 29.744  1    39.81  ? 242 PHE D N   1 
ATOM   591  C  CA  . PHE A 1 72  ? -31.015 -15.084 30.262  1    37.27  ? 242 PHE D CA  1 
ATOM   592  C  C   . PHE A 1 72  ? -30.363 -16.409 29.87   1    39.77  ? 242 PHE D C   1 
ATOM   593  O  O   . PHE A 1 72  ? -29.251 -16.439 29.339  1    43.14  ? 242 PHE D O   1 
ATOM   594  C  CB  . PHE A 1 72  ? -31.041 -14.943 31.783  1    32.94  ? 242 PHE D CB  1 
ATOM   595  C  CG  . PHE A 1 72  ? -29.631 -14.729 32.311  1    32.85  ? 242 PHE D CG  1 
ATOM   596  C  CD1 . PHE A 1 72  ? -29.051 -13.48  32.266  1    33.68  ? 242 PHE D CD1 1 
ATOM   597  C  CD2 . PHE A 1 72  ? -28.883 -15.782 32.837  1    34.34  ? 242 PHE D CD2 1 
ATOM   598  C  CE1 . PHE A 1 72  ? -27.772 -13.293 32.753  1    36.23  ? 242 PHE D CE1 1 
ATOM   599  C  CE2 . PHE A 1 72  ? -27.6   -15.601 33.316  1    31.2   ? 242 PHE D CE2 1 
ATOM   600  C  CZ  . PHE A 1 72  ? -27.049 -14.352 33.269  1    33.33  ? 242 PHE D CZ  1 
ATOM   601  N  N   . LEU A 1 73  ? -31.065 -17.51  30.14   1    39.03  ? 243 LEU D N   1 
ATOM   602  C  CA  . LEU A 1 73  ? -30.584 -18.842 29.812  1    43.45  ? 243 LEU D CA  1 
ATOM   603  C  C   . LEU A 1 73  ? -30.595 -19.139 28.307  1    41.12  ? 243 LEU D C   1 
ATOM   604  O  O   . LEU A 1 73  ? -30.102 -20.185 27.909  1    40.97  ? 243 LEU D O   1 
ATOM   605  C  CB  . LEU A 1 73  ? -31.446 -19.847 30.576  1    45.04  ? 243 LEU D CB  1 
ATOM   606  C  CG  . LEU A 1 73  ? -31.344 -19.806 32.105  1    43.89  ? 243 LEU D CG  1 
ATOM   607  C  CD1 . LEU A 1 73  ? -32.25  -20.857 32.718  1    40.56  ? 243 LEU D CD1 1 
ATOM   608  C  CD2 . LEU A 1 73  ? -29.907 -20.001 32.579  1    45.43  ? 243 LEU D CD2 1 
ATOM   609  N  N   . SER A 1 74  ? -31.151 -18.254 27.468  1    40.64  ? 244 SER D N   1 
ATOM   610  C  CA  . SER A 1 74  ? -31.01  -18.394 26.019  1    41.86  ? 244 SER D CA  1 
ATOM   611  C  C   . SER A 1 74  ? -29.672 -17.838 25.525  1    40.91  ? 244 SER D C   1 
ATOM   612  O  O   . SER A 1 74  ? -29.285 -18.096 24.388  1    41.57  ? 244 SER D O   1 
ATOM   613  C  CB  . SER A 1 74  ? -32.167 -17.768 25.285  1    42.82  ? 244 SER D CB  1 
ATOM   614  O  OG  . SER A 1 74  ? -33.404 -18.335 25.706  1    49.68  ? 244 SER D OG  1 
ATOM   615  N  N   . SER A 1 75  ? -28.943 -17.134 26.41   1    44.34  ? 245 SER D N   1 
ATOM   616  C  CA  . SER A 1 75  ? -27.742 -16.379 26.055  1    48.47  ? 245 SER D CA  1 
ATOM   617  C  C   . SER A 1 75  ? -26.496 -16.817 26.849  1    48.34  ? 245 SER D C   1 
ATOM   618  O  O   . SER A 1 75  ? -25.374 -16.676 26.368  1    53.87  ? 245 SER D O   1 
ATOM   619  C  CB  . SER A 1 75  ? -27.986 -14.883 26.186  1    55.03  ? 245 SER D CB  1 
ATOM   620  O  OG  . SER A 1 75  ? -29.315 -14.508 25.822  1    63.08  ? 245 SER D OG  1 
ATOM   621  N  N   . MET A 1 76  ? -26.66  -17.345 28.068  1    45.21  ? 246 MET D N   1 
ATOM   622  C  CA  . MET A 1 76  ? -25.508 -17.592 28.929  1    43.68  ? 246 MET D CA  1 
ATOM   623  C  C   . MET A 1 76  ? -25.572 -19.015 29.482  1    45.41  ? 246 MET D C   1 
ATOM   624  O  O   . MET A 1 76  ? -26.632 -19.466 29.926  1    47.79  ? 246 MET D O   1 
ATOM   625  C  CB  . MET A 1 76  ? -25.506 -16.639 30.129  1    41.13  ? 246 MET D CB  1 
ATOM   626  C  CG  . MET A 1 76  ? -25.74  -15.182 29.787  1    41.23  ? 246 MET D CG  1 
ATOM   627  S  SD  . MET A 1 76  ? -24.245 -14.317 29.295  1    47.96  ? 246 MET D SD  1 
ATOM   628  C  CE  . MET A 1 76  ? -23.329 -14.546 30.826  1    39.66  ? 246 MET D CE  1 
ATOM   629  N  N   . SER A 1 77  ? -24.438 -19.722 29.459  1    44.23  ? 247 SER D N   1 
ATOM   630  C  CA  . SER A 1 77  ? -24.381 -21.01  30.129  1    42.76  ? 247 SER D CA  1 
ATOM   631  C  C   . SER A 1 77  ? -24.317 -20.77  31.634  1    46.12  ? 247 SER D C   1 
ATOM   632  O  O   . SER A 1 77  ? -23.694 -19.827 32.119  1    50.37  ? 247 SER D O   1 
ATOM   633  C  CB  . SER A 1 77  ? -23.203 -21.801 29.665  1    41.84  ? 247 SER D CB  1 
ATOM   634  O  OG  . SER A 1 77  ? -23.396 -22.19  28.315  1    45.64  ? 247 SER D OG  1 
ATOM   635  N  N   . VAL A 1 78  ? -25.079 -21.568 32.387  1    45.08  ? 248 VAL D N   1 
ATOM   636  C  CA  . VAL A 1 78  ? -25.155 -21.336 33.862  1    44.14  ? 248 VAL D CA  1 
ATOM   637  C  C   . VAL A 1 78  ? -25.024 -22.686 34.583  1    44.86  ? 248 VAL D C   1 
ATOM   638  O  O   . VAL A 1 78  ? -25.68  -23.657 34.146  1    47.22  ? 248 VAL D O   1 
ATOM   639  C  CB  . VAL A 1 78  ? -26.465 -20.618 34.245  1    41.32  ? 248 VAL D CB  1 
ATOM   640  C  CG1 . VAL A 1 78  ? -26.722 -20.641 35.746  1    38.39  ? 248 VAL D CG1 1 
ATOM   641  C  CG2 . VAL A 1 78  ? -26.509 -19.185 33.726  1    37.27  ? 248 VAL D CG2 1 
ATOM   642  N  N   . LEU A 1 79  ? -24.139 -22.792 35.567  1    47.22  ? 249 LEU D N   1 
ATOM   643  C  CA  . LEU A 1 79  ? -23.951 -24.077 36.28   1    45.74  ? 249 LEU D CA  1 
ATOM   644  C  C   . LEU A 1 79  ? -25.112 -24.266 37.268  1    47.41  ? 249 LEU D C   1 
ATOM   645  O  O   . LEU A 1 79  ? -25.671 -23.255 37.702  1    48.39  ? 249 LEU D O   1 
ATOM   646  C  CB  . LEU A 1 79  ? -22.579 -24.097 36.943  1    42.07  ? 249 LEU D CB  1 
ATOM   647  C  CG  . LEU A 1 79  ? -21.383 -24.13  35.991  1    44.91  ? 249 LEU D CG  1 
ATOM   648  C  CD1 . LEU A 1 79  ? -20.164 -24.652 36.718  1    44.38  ? 249 LEU D CD1 1 
ATOM   649  C  CD2 . LEU A 1 79  ? -21.688 -24.983 34.777  1    42.35  ? 249 LEU D CD2 1 
ATOM   650  N  N   . ARG A 1 80  ? -25.466 -25.51  37.594  1    47.62  ? 250 ARG D N   1 
ATOM   651  C  CA  . ARG A 1 80  ? -26.623 -25.806 38.482  1    46.82  ? 250 ARG D CA  1 
ATOM   652  C  C   . ARG A 1 80  ? -26.52  -25.012 39.784  1    47.76  ? 250 ARG D C   1 
ATOM   653  O  O   . ARG A 1 80  ? -27.556 -24.552 40.285  1    44.96  ? 250 ARG D O   1 
ATOM   654  C  CB  . ARG A 1 80  ? -26.66  -27.303 38.791  1    46.74  ? 250 ARG D CB  1 
ATOM   655  C  CG  . ARG A 1 80  ? -27.846 -27.757 39.628  1    50.65  ? 250 ARG D CG  1 
ATOM   656  C  CD  . ARG A 1 80  ? -27.502 -28.967 40.473  1    56.13  ? 250 ARG D CD  1 
ATOM   657  N  NE  . ARG A 1 80  ? -26.093 -29.345 40.331  1    56.44  ? 250 ARG D NE  1 
ATOM   658  C  CZ  . ARG A 1 80  ? -25.64  -30.587 40.4    1    58.29  ? 250 ARG D CZ  1 
ATOM   659  N  NH1 . ARG A 1 80  ? -24.663 -30.885 41.234  1    57.9   ? 250 ARG D NH1 1 
ATOM   660  N  NH2 . ARG A 1 80  ? -26.165 -31.525 39.636  1    58.05  ? 250 ARG D NH2 1 
ATOM   661  N  N   . GLY A 1 81  ? -25.309 -24.855 40.298  1    47.46  ? 251 GLY D N   1 
ATOM   662  C  CA  . GLY A 1 81  ? -25.106 -24.151 41.57   1    46.67  ? 251 GLY D CA  1 
ATOM   663  C  C   . GLY A 1 81  ? -25.431 -22.684 41.456  1    46.22  ? 251 GLY D C   1 
ATOM   664  O  O   . GLY A 1 81  ? -25.625 -22.048 42.5    1    45.23  ? 251 GLY D O   1 
ATOM   665  N  N   . LYS A 1 82  ? -25.476 -22.166 40.229  1    41.96  ? 252 LYS D N   1 
ATOM   666  C  CA  . LYS A 1 82  ? -25.741 -20.715 40.04   1    41.93  ? 252 LYS D CA  1 
ATOM   667  C  C   . LYS A 1 82  ? -27.158 -20.513 39.483  1    41.02  ? 252 LYS D C   1 
ATOM   668  O  O   . LYS A 1 82  ? -27.588 -19.346 39.365  1    41.93  ? 252 LYS D O   1 
ATOM   669  C  CB  . LYS A 1 82  ? -24.691 -20.119 39.098  1    37.52  ? 252 LYS D CB  1 
ATOM   670  C  CG  . LYS A 1 82  ? -23.268 -20.234 39.616  1    39.89  ? 252 LYS D CG  1 
ATOM   671  C  CD  . LYS A 1 82  ? -23.1   -19.59  40.987  1    38.15  ? 252 LYS D CD  1 
ATOM   672  C  CE  . LYS A 1 82  ? -21.798 -18.869 41.131  1    37.29  ? 252 LYS D CE  1 
ATOM   673  N  NZ  . LYS A 1 82  ? -21.03  -18.86  39.883  1    42.72  ? 252 LYS D NZ  1 
ATOM   674  N  N   . LEU A 1 83  ? -27.846 -21.607 39.148  1    41.95  ? 253 LEU D N   1 
ATOM   675  C  CA  . LEU A 1 83  ? -29.219 -21.504 38.59   1    39.18  ? 253 LEU D CA  1 
ATOM   676  C  C   . LEU A 1 83  ? -30.086 -20.663 39.539  1    39.83  ? 253 LEU D C   1 
ATOM   677  O  O   . LEU A 1 83  ? -30.787 -19.751 39.048  1    39.54  ? 253 LEU D O   1 
ATOM   678  C  CB  . LEU A 1 83  ? -29.806 -22.898 38.38   1    43.55  ? 253 LEU D CB  1 
ATOM   679  C  CG  . LEU A 1 83  ? -31.014 -22.976 37.442  1    41.63  ? 253 LEU D CG  1 
ATOM   680  C  CD1 . LEU A 1 83  ? -30.783 -22.12  36.209  1    36.75  ? 253 LEU D CD1 1 
ATOM   681  C  CD2 . LEU A 1 83  ? -31.304 -24.414 37.05   1    41.44  ? 253 LEU D CD2 1 
ATOM   682  N  N   . GLN A 1 84  ? -30.038 -20.953 40.843  1    38.57  ? 254 GLN D N   1 
ATOM   683  C  CA  . GLN A 1 84  ? -30.882 -20.231 41.778  1    39.8   ? 254 GLN D CA  1 
ATOM   684  C  C   . GLN A 1 84  ? -30.478 -18.755 41.848  1    40.66  ? 254 GLN D C   1 
ATOM   685  O  O   . GLN A 1 84  ? -31.325 -17.885 42.072  1    42.71  ? 254 GLN D O   1 
ATOM   686  C  CB  . GLN A 1 84  ? -30.896 -20.878 43.161  1    40.58  ? 254 GLN D CB  1 
ATOM   687  C  CG  . GLN A 1 84  ? -32.093 -20.454 44.005  1    39.24  ? 254 GLN D CG  1 
ATOM   688  C  CD  . GLN A 1 84  ? -32.147 -21.131 45.358  1    42.95  ? 254 GLN D CD  1 
ATOM   689  O  OE1 . GLN A 1 84  ? -33.104 -20.939 46.103  1    45.8   ? 254 GLN D OE1 1 
ATOM   690  N  NE2 . GLN A 1 84  ? -31.166 -21.96  45.696  1    42.94  ? 254 GLN D NE2 1 
ATOM   691  N  N   . LEU A 1 85  ? -29.189 -18.453 41.671  1    38.35  ? 255 LEU D N   1 
ATOM   692  C  CA  . LEU A 1 85  ? -28.793 -17.055 41.728  1    38.89  ? 255 LEU D CA  1 
ATOM   693  C  C   . LEU A 1 85  ? -29.453 -16.282 40.579  1    41.67  ? 255 LEU D C   1 
ATOM   694  O  O   . LEU A 1 85  ? -29.94  -15.171 40.768  1    41.28  ? 255 LEU D O   1 
ATOM   695  C  CB  . LEU A 1 85  ? -27.274 -16.975 41.694  1    37.8   ? 255 LEU D CB  1 
ATOM   696  C  CG  . LEU A 1 85  ? -26.685 -15.579 41.886  1    36.83  ? 255 LEU D CG  1 
ATOM   697  C  CD1 . LEU A 1 85  ? -27.185 -14.917 43.169  1    34.83  ? 255 LEU D CD1 1 
ATOM   698  C  CD2 . LEU A 1 85  ? -25.186 -15.717 41.905  1    35.22  ? 255 LEU D CD2 1 
ATOM   699  N  N   . VAL A 1 86  ? -29.501 -16.892 39.386  1    42.56  ? 256 VAL D N   1 
ATOM   700  C  CA  . VAL A 1 86  ? -30.176 -16.275 38.261  1    37.79  ? 256 VAL D CA  1 
ATOM   701  C  C   . VAL A 1 86  ? -31.639 -16.027 38.642  1    38.02  ? 256 VAL D C   1 
ATOM   702  O  O   . VAL A 1 86  ? -32.119 -14.906 38.563  1    37.08  ? 256 VAL D O   1 
ATOM   703  C  CB  . VAL A 1 86  ? -30.04  -17.118 36.986  1    37.05  ? 256 VAL D CB  1 
ATOM   704  C  CG1 . VAL A 1 86  ? -30.851 -16.52  35.843  1    34.02  ? 256 VAL D CG1 1 
ATOM   705  C  CG2 . VAL A 1 86  ? -28.58  -17.283 36.578  1    39.79  ? 256 VAL D CG2 1 
ATOM   706  N  N   . GLY A 1 87  ? -32.331 -17.063 39.123  1    40.11  ? 257 GLY D N   1 
ATOM   707  C  CA  . GLY A 1 87  ? -33.741 -16.982 39.478  1    36.62  ? 257 GLY D CA  1 
ATOM   708  C  C   . GLY A 1 87  ? -34.021 -15.889 40.51   1    37.17  ? 257 GLY D C   1 
ATOM   709  O  O   . GLY A 1 87  ? -35.021 -15.195 40.402  1    39.17  ? 257 GLY D O   1 
ATOM   710  N  N   . THR A 1 88  ? -33.15  -15.738 41.515  1    37.89  ? 258 THR D N   1 
ATOM   711  C  CA  . THR A 1 88  ? -33.349 -14.763 42.593  1    39.07  ? 258 THR D CA  1 
ATOM   712  C  C   . THR A 1 88  ? -33.196 -13.351 42.02   1    38.79  ? 258 THR D C   1 
ATOM   713  O  O   . THR A 1 88  ? -33.976 -12.441 42.322  1    36.75  ? 258 THR D O   1 
ATOM   714  C  CB  . THR A 1 88  ? -32.327 -14.984 43.712  1    36.87  ? 258 THR D CB  1 
ATOM   715  O  OG1 . THR A 1 88  ? -32.407 -16.337 44.145  1    39.64  ? 258 THR D OG1 1 
ATOM   716  C  CG2 . THR A 1 88  ? -32.552 -14.074 44.896  1    36.04  ? 258 THR D CG2 1 
ATOM   717  N  N   . ALA A 1 89  ? -32.161 -13.187 41.185  1    37.19  ? 259 ALA D N   1 
ATOM   718  C  CA  . ALA A 1 89  ? -31.889 -11.904 40.563  1    35.57  ? 259 ALA D CA  1 
ATOM   719  C  C   . ALA A 1 89  ? -33.081 -11.509 39.692  1    35.99  ? 259 ALA D C   1 
ATOM   720  O  O   . ALA A 1 89  ? -33.541 -10.373 39.778  1    38.1   ? 259 ALA D O   1 
ATOM   721  C  CB  . ALA A 1 89  ? -30.615 -11.997 39.799  1    30.96  ? 259 ALA D CB  1 
ATOM   722  N  N   . ALA A 1 90  ? -33.664 -12.452 38.964  1    33.55  ? 260 ALA D N   1 
ATOM   723  C  CA  . ALA A 1 90  ? -34.787 -12.144 38.049  1    33.76  ? 260 ALA D CA  1 
ATOM   724  C  C   . ALA A 1 90  ? -36.063 -11.779 38.805  1    38.41  ? 260 ALA D C   1 
ATOM   725  O  O   . ALA A 1 90  ? -36.8   -10.92  38.318  1    42.86  ? 260 ALA D O   1 
ATOM   726  C  CB  . ALA A 1 90  ? -35.025 -13.316 37.149  1    31.99  ? 260 ALA D CB  1 
ATOM   727  N  N   . MET A 1 91  ? -36.327 -12.428 39.933  1    37.63  ? 261 MET D N   1 
ATOM   728  C  CA  . MET A 1 91  ? -37.507 -12.077 40.761  1    39.27  ? 261 MET D CA  1 
ATOM   729  C  C   . MET A 1 91  ? -37.292 -10.684 41.368  1    41.51  ? 261 MET D C   1 
ATOM   730  O  O   . MET A 1 91  ? -38.26  -9.92   41.428  1    42.16  ? 261 MET D O   1 
ATOM   731  C  CB  . MET A 1 91  ? -37.752 -13.132 41.844  1    36.65  ? 261 MET D CB  1 
ATOM   732  C  CG  . MET A 1 91  ? -38.98  -12.888 42.69   1    40     ? 261 MET D CG  1 
ATOM   733  S  SD  . MET A 1 91  ? -40.506 -13.026 41.743  1    44.65  ? 261 MET D SD  1 
ATOM   734  C  CE  . MET A 1 91  ? -40.626 -14.807 41.557  1    42.94  ? 261 MET D CE  1 
ATOM   735  N  N   . LEU A 1 92  ? -36.068 -10.367 41.778  1    38.92  ? 262 LEU D N   1 
ATOM   736  C  CA  . LEU A 1 92  ? -35.768 -9.011  42.291  1    36.81  ? 262 LEU D CA  1 
ATOM   737  C  C   . LEU A 1 92  ? -36.08  -7.98   41.194  1    36.91  ? 262 LEU D C   1 
ATOM   738  O  O   . LEU A 1 92  ? -36.738 -6.984  41.505  1    36.75  ? 262 LEU D O   1 
ATOM   739  C  CB  . LEU A 1 92  ? -34.317 -8.957  42.762  1    34.31  ? 262 LEU D CB  1 
ATOM   740  C  CG  . LEU A 1 92  ? -33.776 -7.589  43.18   1    34.62  ? 262 LEU D CG  1 
ATOM   741  C  CD1 . LEU A 1 92  ? -34.533 -7.054  44.376  1    33.48  ? 262 LEU D CD1 1 
ATOM   742  C  CD2 . LEU A 1 92  ? -32.305 -7.726  43.504  1    34.2   ? 262 LEU D CD2 1 
ATOM   743  N  N   . LEU A 1 93  ? -35.637 -8.233  39.961  1    34.65  ? 263 LEU D N   1 
ATOM   744  C  CA  . LEU A 1 93  ? -35.897 -7.27   38.901  1    34.54  ? 263 LEU D CA  1 
ATOM   745  C  C   . LEU A 1 93  ? -37.391 -7.157  38.607  1    36.7   ? 263 LEU D C   1 
ATOM   746  O  O   . LEU A 1 93  ? -37.903 -6.038  38.547  1    37.87  ? 263 LEU D O   1 
ATOM   747  C  CB  . LEU A 1 93  ? -35.091 -7.672  37.672  1    38.59  ? 263 LEU D CB  1 
ATOM   748  C  CG  . LEU A 1 93  ? -33.581 -7.391  37.743  1    42.33  ? 263 LEU D CG  1 
ATOM   749  C  CD1 . LEU A 1 93  ? -32.878 -8.056  36.563  1    36.59  ? 263 LEU D CD1 1 
ATOM   750  C  CD2 . LEU A 1 93  ? -33.301 -5.865  37.745  1    39.58  ? 263 LEU D CD2 1 
ATOM   751  N  N   . ALA A 1 94  ? -38.08  -8.311  38.48   1    33.68  ? 264 ALA D N   1 
ATOM   752  C  CA  . ALA A 1 94  ? -39.515 -8.367  38.249  1    33.4   ? 264 ALA D CA  1 
ATOM   753  C  C   . ALA A 1 94  ? -40.243 -7.546  39.304  1    36.84  ? 264 ALA D C   1 
ATOM   754  O  O   . ALA A 1 94  ? -41.105 -6.738  38.988  1    40.7   ? 264 ALA D O   1 
ATOM   755  C  CB  . ALA A 1 94  ? -39.996 -9.786  38.313  1    31.72  ? 264 ALA D CB  1 
ATOM   756  N  N   . SER A 1 95  ? -39.898 -7.781  40.568  1    38.12  ? 265 SER D N   1 
ATOM   757  C  CA  . SER A 1 95  ? -40.49  -7.073  41.688  1    37.85  ? 265 SER D CA  1 
ATOM   758  C  C   . SER A 1 95  ? -40.259 -5.567  41.55   1    40.06  ? 265 SER D C   1 
ATOM   759  O  O   . SER A 1 95  ? -41.188 -4.782  41.774  1    40.16  ? 265 SER D O   1 
ATOM   760  C  CB  . SER A 1 95  ? -39.922 -7.571  42.975  1    39.46  ? 265 SER D CB  1 
ATOM   761  O  OG  . SER A 1 95  ? -40.177 -8.959  43.133  1    42.01  ? 265 SER D OG  1 
ATOM   762  N  N   . LYS A 1 96  ? -39.03  -5.165  41.187  1    35     ? 266 LYS D N   1 
ATOM   763  C  CA  . LYS A 1 96  ? -38.733 -3.747  41.103  1    35.38  ? 266 LYS D CA  1 
ATOM   764  C  C   . LYS A 1 96  ? -39.512 -3.12   39.95   1    36.69  ? 266 LYS D C   1 
ATOM   765  O  O   . LYS A 1 96  ? -39.944 -1.966  40.043  1    38.98  ? 266 LYS D O   1 
ATOM   766  C  CB  . LYS A 1 96  ? -37.241 -3.486  40.909  1    35.98  ? 266 LYS D CB  1 
ATOM   767  C  CG  . LYS A 1 96  ? -36.36  -3.681  42.135  1    32.6   ? 266 LYS D CG  1 
ATOM   768  C  CD  . LYS A 1 96  ? -34.993 -3.044  41.905  1    33.18  ? 266 LYS D CD  1 
ATOM   769  C  CE  . LYS A 1 96  ? -34.024 -3.59   42.922  1    34.22  ? 266 LYS D CE  1 
ATOM   770  N  NZ  . LYS A 1 96  ? -32.67  -3.044  42.777  1    32.13  ? 266 LYS D NZ  1 
ATOM   771  N  N   . PHE A 1 97  ? -39.733 -3.905  38.886  1    35.05  ? 267 PHE D N   1 
ATOM   772  C  CA  . PHE A 1 97  ? -40.441 -3.399  37.723  1    33.73  ? 267 PHE D CA  1 
ATOM   773  C  C   . PHE A 1 97  ? -41.927 -3.216  38.025  1    34.65  ? 267 PHE D C   1 
ATOM   774  O  O   . PHE A 1 97  ? -42.498 -2.186  37.661  1    32.24  ? 267 PHE D O   1 
ATOM   775  C  CB  . PHE A 1 97  ? -40.239 -4.315  36.518  1    30.65  ? 267 PHE D CB  1 
ATOM   776  C  CG  . PHE A 1 97  ? -40.974 -3.874  35.264  1    31.76  ? 267 PHE D CG  1 
ATOM   777  C  CD1 . PHE A 1 97  ? -40.394 -3.002  34.352  1    34.46  ? 267 PHE D CD1 1 
ATOM   778  C  CD2 . PHE A 1 97  ? -42.254 -4.333  34.995  1    34.59  ? 267 PHE D CD2 1 
ATOM   779  C  CE1 . PHE A 1 97  ? -41.068 -2.606  33.197  1    37.01  ? 267 PHE D CE1 1 
ATOM   780  C  CE2 . PHE A 1 97  ? -42.921 -3.97   33.832  1    37.78  ? 267 PHE D CE2 1 
ATOM   781  C  CZ  . PHE A 1 97  ? -42.332 -3.103  32.93   1    39.8   ? 267 PHE D CZ  1 
ATOM   782  N  N   . GLU A 1 98  ? -42.52  -4.221  38.694  1    35.5   ? 268 GLU D N   1 
ATOM   783  C  CA  . GLU A 1 98  ? -43.959 -4.433  38.696  1    37.14  ? 268 GLU D CA  1 
ATOM   784  C  C   . GLU A 1 98  ? -44.636 -4.08   40.026  1    38.07  ? 268 GLU D C   1 
ATOM   785  O  O   . GLU A 1 98  ? -45.82  -3.781  40.028  1    40.58  ? 268 GLU D O   1 
ATOM   786  C  CB  . GLU A 1 98  ? -44.236 -5.891  38.345  1    35.01  ? 268 GLU D CB  1 
ATOM   787  C  CG  . GLU A 1 98  ? -45.706 -6.13   38.011  1    41.13  ? 268 GLU D CG  1 
ATOM   788  C  CD  . GLU A 1 98  ? -46.21  -5.321  36.826  1    45.26  ? 268 GLU D CD  1 
ATOM   789  O  OE1 . GLU A 1 98  ? -45.447 -5.06   35.86   1    44.23  ? 268 GLU D OE1 1 
ATOM   790  O  OE2 . GLU A 1 98  ? -47.407 -4.986  36.866  1    43.86  ? 268 GLU D OE2 1 
ATOM   791  N  N   . GLU A 1 99  ? -43.923 -4.12   41.155  1    38.46  ? 269 GLU D N   1 
ATOM   792  C  CA  . GLU A 1 99  ? -44.598 -4.105  42.446  1    38.08  ? 269 GLU D CA  1 
ATOM   793  C  C   . GLU A 1 99  ? -44.621 -2.683  42.984  1    40.78  ? 269 GLU D C   1 
ATOM   794  O  O   . GLU A 1 99  ? -43.643 -1.955  42.86   1    42.66  ? 269 GLU D O   1 
ATOM   795  C  CB  . GLU A 1 99  ? -43.855 -4.986  43.448  1    37.86  ? 269 GLU D CB  1 
ATOM   796  C  CG  . GLU A 1 99  ? -43.955 -6.484  43.163  1    37.61  ? 269 GLU D CG  1 
ATOM   797  C  CD  . GLU A 1 99  ? -45.297 -7.123  43.495  1    43.4   ? 269 GLU D CD  1 
ATOM   798  O  OE1 . GLU A 1 99  ? -46.05  -6.615  44.361  1    47.72  ? 269 GLU D OE1 1 
ATOM   799  O  OE2 . GLU A 1 99  ? -45.633 -8.118  42.824  1    41.16  ? 269 GLU D OE2 1 
ATOM   800  N  N   . ILE A 1 100 ? -45.747 -2.287  43.574  1    41.54  ? 270 ILE D N   1 
ATOM   801  C  CA  . ILE A 1 100 ? -45.765 -1.037  44.295  1    42.05  ? 270 ILE D CA  1 
ATOM   802  C  C   . ILE A 1 100 ? -44.676 -1.041  45.385  1    45.31  ? 270 ILE D C   1 
ATOM   803  O  O   . ILE A 1 100 ? -43.976 -0.049  45.578  1    45.17  ? 270 ILE D O   1 
ATOM   804  C  CB  . ILE A 1 100 ? -47.159 -0.782  44.887  1    44.59  ? 270 ILE D CB  1 
ATOM   805  C  CG1 . ILE A 1 100 ? -48.288 -0.728  43.843  1    43.48  ? 270 ILE D CG1 1 
ATOM   806  C  CG2 . ILE A 1 100 ? -47.123 0.487   45.74   1    44.62  ? 270 ILE D CG2 1 
ATOM   807  C  CD1 . ILE A 1 100 ? -49.672 -0.539  44.459  1    38.36  ? 270 ILE D CD1 1 
ATOM   808  N  N   . TYR A 1 101 ? -44.569 -2.146  46.141  1    46.92  ? 271 TYR D N   1 
ATOM   809  C  CA  . TYR A 1 101 ? -43.723 -2.244  47.325  1    46.85  ? 271 TYR D CA  1 
ATOM   810  C  C   . TYR A 1 101 ? -42.883 -3.513  47.208  1    45.54  ? 271 TYR D C   1 
ATOM   811  O  O   . TYR A 1 101 ? -43.155 -4.519  47.866  1    45.91  ? 271 TYR D O   1 
ATOM   812  C  CB  . TYR A 1 101 ? -44.532 -2.313  48.632  1    47.32  ? 271 TYR D CB  1 
ATOM   813  C  CG  . TYR A 1 101 ? -45.465 -1.14   48.889  1    51.03  ? 271 TYR D CG  1 
ATOM   814  C  CD1 . TYR A 1 101 ? -44.97  0.072   49.374  1    52.69  ? 271 TYR D CD1 1 
ATOM   815  C  CD2 . TYR A 1 101 ? -46.842 -1.242  48.656  1    52.09  ? 271 TYR D CD2 1 
ATOM   816  C  CE1 . TYR A 1 101 ? -45.811 1.15    49.622  1    55.56  ? 271 TYR D CE1 1 
ATOM   817  C  CE2 . TYR A 1 101 ? -47.691 -0.165  48.89   1    55.08  ? 271 TYR D CE2 1 
ATOM   818  C  CZ  . TYR A 1 101 ? -47.172 1.032   49.363  1    56.41  ? 271 TYR D CZ  1 
ATOM   819  O  OH  . TYR A 1 101 ? -48.016 2.08    49.582  1    64.25  ? 271 TYR D OH  1 
ATOM   820  N  N   . PRO A 1 102 ? -41.831 -3.528  46.357  1    45     ? 272 PRO D N   1 
ATOM   821  C  CA  . PRO A 1 102 ? -41.009 -4.733  46.209  1    41.33  ? 272 PRO D CA  1 
ATOM   822  C  C   . PRO A 1 102 ? -40.347 -5.094  47.536  1    42.98  ? 272 PRO D C   1 
ATOM   823  O  O   . PRO A 1 102 ? -40.03  -4.233  48.355  1    42.82  ? 272 PRO D O   1 
ATOM   824  C  CB  . PRO A 1 102 ? -39.967 -4.308  45.19   1    38.62  ? 272 PRO D CB  1 
ATOM   825  C  CG  . PRO A 1 102 ? -39.907 -2.811  45.321  1    39.97  ? 272 PRO D CG  1 
ATOM   826  C  CD  . PRO A 1 102 ? -41.345 -2.396  45.55   1    40.06  ? 272 PRO D CD  1 
ATOM   827  N  N   . PRO A 1 103 ? -40.118 -6.39   47.811  1    43.3   ? 273 PRO D N   1 
ATOM   828  C  CA  . PRO A 1 103 ? -39.305 -6.75   48.967  1    41.39  ? 273 PRO D CA  1 
ATOM   829  C  C   . PRO A 1 103 ? -37.915 -6.145  48.806  1    43.68  ? 273 PRO D C   1 
ATOM   830  O  O   . PRO A 1 103 ? -37.397 -5.955  47.699  1    40.18  ? 273 PRO D O   1 
ATOM   831  C  CB  . PRO A 1 103 ? -39.283 -8.28   48.926  1    39.68  ? 273 PRO D CB  1 
ATOM   832  C  CG  . PRO A 1 103 ? -40.504 -8.658  48.09   1    40.56  ? 273 PRO D CG  1 
ATOM   833  C  CD  . PRO A 1 103 ? -40.67  -7.546  47.07   1    40.42  ? 273 PRO D CD  1 
ATOM   834  N  N   . GLU A 1 104 ? -37.295 -5.881  49.956  1    48.44  ? 274 GLU D N   1 
ATOM   835  C  CA  . GLU A 1 104 ? -35.935 -5.381  50      1    51.47  ? 274 GLU D CA  1 
ATOM   836  C  C   . GLU A 1 104 ? -34.969 -6.469  49.542  1    46.34  ? 274 GLU D C   1 
ATOM   837  O  O   . GLU A 1 104 ? -35.305 -7.649  49.527  1    44.67  ? 274 GLU D O   1 
ATOM   838  C  CB  . GLU A 1 104 ? -35.709 -4.903  51.431  1    62.26  ? 274 GLU D CB  1 
ATOM   839  C  CG  . GLU A 1 104 ? -35.089 -3.515  51.422  1    77.17  ? 274 GLU D CG  1 
ATOM   840  C  CD  . GLU A 1 104 ? -35.649 -2.669  52.531  1    89.7   ? 274 GLU D CD  1 
ATOM   841  O  OE1 . GLU A 1 104 ? -36.452 -1.775  52.18   1    89.8   ? 274 GLU D OE1 1 
ATOM   842  O  OE2 . GLU A 1 104 ? -35.27  -2.897  53.705  1    97     ? 274 GLU D OE2 1 
ATOM   843  N  N   . VAL A 1 105 ? -33.767 -6.053  49.144  1    43.22  ? 275 VAL D N   1 
ATOM   844  C  CA  . VAL A 1 105 ? -32.782 -7.006  48.653  1    44.67  ? 275 VAL D CA  1 
ATOM   845  C  C   . VAL A 1 105 ? -32.42  -8.061  49.711  1    46.41  ? 275 VAL D C   1 
ATOM   846  O  O   . VAL A 1 105 ? -32.195 -9.227  49.373  1    44.32  ? 275 VAL D O   1 
ATOM   847  C  CB  . VAL A 1 105 ? -31.537 -6.272  48.124  1    43.5   ? 275 VAL D CB  1 
ATOM   848  C  CG1 . VAL A 1 105 ? -30.427 -7.26   47.802  1    42.94  ? 275 VAL D CG1 1 
ATOM   849  C  CG2 . VAL A 1 105 ? -31.878 -5.414  46.908  1    45.71  ? 275 VAL D CG2 1 
ATOM   850  N  N   . ALA A 1 106 ? -32.325 -7.639  50.984  1    46.52  ? 276 ALA D N   1 
ATOM   851  C  CA  . ALA A 1 106 ? -32.063 -8.57   52.069  1    49.89  ? 276 ALA D CA  1 
ATOM   852  C  C   . ALA A 1 106 ? -33.031 -9.758  52.026  1    50.47  ? 276 ALA D C   1 
ATOM   853  O  O   . ALA A 1 106 ? -32.614 -10.893 52.187  1    53.86  ? 276 ALA D O   1 
ATOM   854  C  CB  . ALA A 1 106 ? -32.112 -7.857  53.4    1    47.91  ? 276 ALA D CB  1 
ATOM   855  N  N   . GLU A 1 107 ? -34.323 -9.495  51.829  1    49.55  ? 277 GLU D N   1 
ATOM   856  C  CA  . GLU A 1 107 ? -35.338 -10.535 51.832  1    50.56  ? 277 GLU D CA  1 
ATOM   857  C  C   . GLU A 1 107 ? -35.05  -11.558 50.729  1    49.84  ? 277 GLU D C   1 
ATOM   858  O  O   . GLU A 1 107 ? -35.27  -12.742 50.936  1    55.86  ? 277 GLU D O   1 
ATOM   859  C  CB  . GLU A 1 107 ? -36.744 -9.928  51.806  1    53.02  ? 277 GLU D CB  1 
ATOM   860  C  CG  . GLU A 1 107 ? -37.17  -9.216  53.095  1    64.58  ? 277 GLU D CG  1 
ATOM   861  C  CD  . GLU A 1 107 ? -38.477 -8.403  52.997  1    88.1   ? 277 GLU D CD  1 
ATOM   862  O  OE1 . GLU A 1 107 ? -39.464 -8.81   53.669  1    102.52 ? 277 GLU D OE1 1 
ATOM   863  O  OE2 . GLU A 1 107 ? -38.561 -7.371  52.274  1    87.46  ? 277 GLU D OE2 1 
ATOM   864  N  N   . PHE A 1 108 ? -34.498 -11.125 49.585  1    46.47  ? 278 PHE D N   1 
ATOM   865  C  CA  . PHE A 1 108 ? -34.143 -12.032 48.499  1    41.9   ? 278 PHE D CA  1 
ATOM   866  C  C   . PHE A 1 108 ? -32.918 -12.886 48.85   1    44.52  ? 278 PHE D C   1 
ATOM   867  O  O   . PHE A 1 108 ? -32.715 -13.958 48.265  1    46.54  ? 278 PHE D O   1 
ATOM   868  C  CB  . PHE A 1 108 ? -33.906 -11.269 47.189  1    37.84  ? 278 PHE D CB  1 
ATOM   869  C  CG  . PHE A 1 108 ? -35.209 -10.812 46.561  1    39.22  ? 278 PHE D CG  1 
ATOM   870  C  CD1 . PHE A 1 108 ? -35.957 -11.697 45.771  1    39.71  ? 278 PHE D CD1 1 
ATOM   871  C  CD2 . PHE A 1 108 ? -35.713 -9.528  46.802  1    37.76  ? 278 PHE D CD2 1 
ATOM   872  C  CE1 . PHE A 1 108 ? -37.179 -11.311 45.219  1    37.61  ? 278 PHE D CE1 1 
ATOM   873  C  CE2 . PHE A 1 108 ? -36.94  -9.148  46.254  1    37.9   ? 278 PHE D CE2 1 
ATOM   874  C  CZ  . PHE A 1 108 ? -37.665 -10.026 45.451  1    36.05  ? 278 PHE D CZ  1 
ATOM   875  N  N   . VAL A 1 109 ? -32.063 -12.411 49.744  1    42.73  ? 279 VAL D N   1 
ATOM   876  C  CA  . VAL A 1 109 ? -30.849 -13.189 50.122  1    49.22  ? 279 VAL D CA  1 
ATOM   877  C  C   . VAL A 1 109 ? -31.268 -14.217 51.18   1    55.09  ? 279 VAL D C   1 
ATOM   878  O  O   . VAL A 1 109 ? -30.583 -15.244 51.325  1    62.21  ? 279 VAL D O   1 
ATOM   879  C  CB  . VAL A 1 109 ? -29.703 -12.286 50.613  1    46.89  ? 279 VAL D CB  1 
ATOM   880  C  CG1 . VAL A 1 109 ? -28.404 -13.051 50.809  1    44.23  ? 279 VAL D CG1 1 
ATOM   881  C  CG2 . VAL A 1 109 ? -29.485 -11.104 49.682  1    44.09  ? 279 VAL D CG2 1 
ATOM   882  N  N   . TYR A 1 110 ? -32.388 -13.967 51.846  1    53.72  ? 280 TYR D N   1 
ATOM   883  C  CA  . TYR A 1 110 ? -32.841 -14.861 52.933  1    54.48  ? 280 TYR D CA  1 
ATOM   884  C  C   . TYR A 1 110 ? -33.55  -16.068 52.355  1    52.89  ? 280 TYR D C   1 
ATOM   885  O  O   . TYR A 1 110 ? -33.422 -17.164 52.917  1    53.68  ? 280 TYR D O   1 
ATOM   886  C  CB  . TYR A 1 110 ? -33.733 -13.985 53.811  1    60.97  ? 280 TYR D CB  1 
ATOM   887  C  CG  . TYR A 1 110 ? -34.487 -14.765 54.877  1    78.43  ? 280 TYR D CG  1 
ATOM   888  C  CD1 . TYR A 1 110 ? -33.84  -15.221 56.017  1    79.86  ? 280 TYR D CD1 1 
ATOM   889  C  CD2 . TYR A 1 110 ? -35.835 -15.063 54.731  1    80.4   ? 280 TYR D CD2 1 
ATOM   890  C  CE1 . TYR A 1 110 ? -34.513 -15.942 56.987  1    83.9   ? 280 TYR D CE1 1 
ATOM   891  C  CE2 . TYR A 1 110 ? -36.519 -15.784 55.694  1    83.15  ? 280 TYR D CE2 1 
ATOM   892  C  CZ  . TYR A 1 110 ? -35.857 -16.223 56.825  1    87.67  ? 280 TYR D CZ  1 
ATOM   893  O  OH  . TYR A 1 110 ? -36.522 -16.933 57.781  1    92.89  ? 280 TYR D OH  1 
ATOM   894  N  N   . ILE A 1 111 ? -34.265 -15.888 51.25   1    55.77  ? 281 ILE D N   1 
ATOM   895  C  CA  . ILE A 1 111 ? -35.064 -17.001 50.66   1    60.97  ? 281 ILE D CA  1 
ATOM   896  C  C   . ILE A 1 111 ? -34.14  -18.051 50.021  1    62.29  ? 281 ILE D C   1 
ATOM   897  O  O   . ILE A 1 111 ? -34.624 -19.16  49.765  1    62.64  ? 281 ILE D O   1 
ATOM   898  C  CB  . ILE A 1 111 ? -36.091 -16.446 49.661  1    58.58  ? 281 ILE D CB  1 
ATOM   899  C  CG1 . ILE A 1 111 ? -35.509 -15.334 48.811  1    53.57  ? 281 ILE D CG1 1 
ATOM   900  C  CG2 . ILE A 1 111 ? -37.355 -15.999 50.389  1    61.98  ? 281 ILE D CG2 1 
ATOM   901  C  CD1 . ILE A 1 111 ? -36.118 -15.229 47.427  1    53.41  ? 281 ILE D CD1 1 
ATOM   902  N  N   . THR A 1 112 ? -32.867 -17.724 49.802  1    59.71  ? 282 THR D N   1 
ATOM   903  C  CA  . THR A 1 112 ? -31.896 -18.672 49.218  1    58.85  ? 282 THR D CA  1 
ATOM   904  C  C   . THR A 1 112 ? -31.213 -19.427 50.324  1    63.4   ? 282 THR D C   1 
ATOM   905  O  O   . THR A 1 112 ? -30.29  -20.181 50.011  1    65.13  ? 282 THR D O   1 
ATOM   906  C  CB  . THR A 1 112 ? -30.881 -17.911 48.37   1    57.59  ? 282 THR D CB  1 
ATOM   907  O  OG1 . THR A 1 112 ? -30.09  -17.157 49.282  1    54.64  ? 282 THR D OG1 1 
ATOM   908  C  CG2 . THR A 1 112 ? -31.547 -16.992 47.364  1    53.71  ? 282 THR D CG2 1 
ATOM   909  N  N   . ASP A 1 113 ? -31.644 -19.238 51.57   1    70.61  ? 283 ASP D N   1 
ATOM   910  C  CA  . ASP A 1 113 ? -31.024 -19.875 52.738  1    75.29  ? 283 ASP D CA  1 
ATOM   911  C  C   . ASP A 1 113 ? -29.535 -19.541 52.879  1    75.47  ? 283 ASP D C   1 
ATOM   912  O  O   . ASP A 1 113 ? -28.741 -20.399 53.288  1    67.03  ? 283 ASP D O   1 
ATOM   913  C  CB  . ASP A 1 113 ? -31.149 -21.391 52.718  1    83.57  ? 283 ASP D CB  1 
ATOM   914  C  CG  . ASP A 1 113 ? -32.541 -21.937 52.963  1    86.94  ? 283 ASP D CG  1 
ATOM   915  O  OD1 . ASP A 1 113 ? -33.405 -21.16  53.439  1    87.04  ? 283 ASP D OD1 1 
ATOM   916  O  OD2 . ASP A 1 113 ? -32.723 -23.132 52.669  1    93.23  ? 283 ASP D OD2 1 
ATOM   917  N  N   . ASP A 1 114 ? -29.169 -18.285 52.569  1    79.26  ? 284 ASP D N   1 
ATOM   918  C  CA  . ASP A 1 114 ? -27.779 -17.842 52.51   1    86.44  ? 284 ASP D CA  1 
ATOM   919  C  C   . ASP A 1 114 ? -26.919 -18.761 51.63   1    77.8   ? 284 ASP D C   1 
ATOM   920  O  O   . ASP A 1 114 ? -25.715 -18.903 51.842  1    70.86  ? 284 ASP D O   1 
ATOM   921  C  CB  . ASP A 1 114 ? -27.21  -17.572 53.897  1    102.27 ? 284 ASP D CB  1 
ATOM   922  C  CG  . ASP A 1 114 ? -28.004 -16.6   54.761  1    104.74 ? 284 ASP D CG  1 
ATOM   923  O  OD1 . ASP A 1 114 ? -28.234 -15.445 54.314  1    100.39 ? 284 ASP D OD1 1 
ATOM   924  O  OD2 . ASP A 1 114 ? -28.379 -17.009 55.881  1    107.21 ? 284 ASP D OD2 1 
ATOM   925  N  N   . THR A 1 115 ? -27.529 -19.354 50.596  1    74.05  ? 285 THR D N   1 
ATOM   926  C  CA  . THR A 1 115 ? -26.755 -20.032 49.569  1    71.58  ? 285 THR D CA  1 
ATOM   927  C  C   . THR A 1 115 ? -25.797 -18.996 48.949  1    67.2   ? 285 THR D C   1 
ATOM   928  O  O   . THR A 1 115 ? -24.624 -19.284 48.7    1    62.23  ? 285 THR D O   1 
ATOM   929  C  CB  . THR A 1 115 ? -27.702 -20.738 48.583  1    70.37  ? 285 THR D CB  1 
ATOM   930  O  OG1 . THR A 1 115 ? -28.474 -21.735 49.248  1    75.22  ? 285 THR D OG1 1 
ATOM   931  C  CG2 . THR A 1 115 ? -26.979 -21.533 47.513  1    71.44  ? 285 THR D CG2 1 
ATOM   932  N  N   . TYR A 1 116 ? -26.287 -17.759 48.765  1    55.37  ? 286 TYR D N   1 
ATOM   933  C  CA  . TYR A 1 116 ? -25.486 -16.7   48.174  1    53.93  ? 286 TYR D CA  1 
ATOM   934  C  C   . TYR A 1 116 ? -25.44  -15.483 49.089  1    55.04  ? 286 TYR D C   1 
ATOM   935  O  O   . TYR A 1 116 ? -26.303 -15.317 49.946  1    57.83  ? 286 TYR D O   1 
ATOM   936  C  CB  . TYR A 1 116 ? -26.104 -16.247 46.855  1    49.34  ? 286 TYR D CB  1 
ATOM   937  C  CG  . TYR A 1 116 ? -26.511 -17.398 45.952  1    51.69  ? 286 TYR D CG  1 
ATOM   938  C  CD1 . TYR A 1 116 ? -25.549 -18.186 45.334  1    50.12  ? 286 TYR D CD1 1 
ATOM   939  C  CD2 . TYR A 1 116 ? -27.852 -17.694 45.722  1    51.13  ? 286 TYR D CD2 1 
ATOM   940  C  CE1 . TYR A 1 116 ? -25.91  -19.25  44.526  1    48.81  ? 286 TYR D CE1 1 
ATOM   941  C  CE2 . TYR A 1 116 ? -28.221 -18.754 44.91   1    48.73  ? 286 TYR D CE2 1 
ATOM   942  C  CZ  . TYR A 1 116 ? -27.247 -19.527 44.307  1    47.52  ? 286 TYR D CZ  1 
ATOM   943  O  OH  . TYR A 1 116 ? -27.581 -20.543 43.471  1    50.57  ? 286 TYR D OH  1 
ATOM   944  N  N   . THR A 1 117 ? -24.415 -14.644 48.871  1    52.14  ? 287 THR D N   1 
ATOM   945  C  CA  . THR A 1 117 ? -24.227 -13.373 49.56   1    51.19  ? 287 THR D CA  1 
ATOM   946  C  C   . THR A 1 117 ? -25.031 -12.28  48.86   1    47.62  ? 287 THR D C   1 
ATOM   947  O  O   . THR A 1 117 ? -25.411 -12.427 47.697  1    45.96  ? 287 THR D O   1 
ATOM   948  C  CB  . THR A 1 117 ? -22.743 -12.986 49.598  1    53.38  ? 287 THR D CB  1 
ATOM   949  O  OG1 . THR A 1 117 ? -22.439 -12.345 48.359  1    51.72  ? 287 THR D OG1 1 
ATOM   950  C  CG2 . THR A 1 117 ? -21.829 -14.173 49.875  1    49.06  ? 287 THR D CG2 1 
ATOM   951  N  N   . LYS A 1 118 ? -25.217 -11.153 49.556  1    46.86  ? 288 LYS D N   1 
ATOM   952  C  CA  . LYS A 1 118 ? -25.922 -10.011 48.997  1    45.8   ? 288 LYS D CA  1 
ATOM   953  C  C   . LYS A 1 118 ? -25.203 -9.499  47.742  1    47.49  ? 288 LYS D C   1 
ATOM   954  O  O   . LYS A 1 118 ? -25.882 -9.075  46.786  1    43.83  ? 288 LYS D O   1 
ATOM   955  C  CB  . LYS A 1 118 ? -26.141 -8.921  50.053  1    47.06  ? 288 LYS D CB  1 
ATOM   956  C  CG  . LYS A 1 118 ? -27.147 -7.857  49.634  1    45.66  ? 288 LYS D CG  1 
ATOM   957  C  CD  . LYS A 1 118 ? -27.877 -7.083  50.731  1    52.36  ? 288 LYS D CD  1 
ATOM   958  C  CE  . LYS A 1 118 ? -27.115 -6.049  51.521  1    57.12  ? 288 LYS D CE  1 
ATOM   959  N  NZ  . LYS A 1 118 ? -28.001 -5.19   52.311  1    60.71  ? 288 LYS D NZ  1 
ATOM   960  N  N   . LYS A 1 119 ? -23.849 -9.537  47.76   1    48.05  ? 289 LYS D N   1 
ATOM   961  C  CA  . LYS A 1 119 ? -23.064 -9.025  46.646  1    48.73  ? 289 LYS D CA  1 
ATOM   962  C  C   . LYS A 1 119 ? -23.295 -9.846  45.385  1    47.96  ? 289 LYS D C   1 
ATOM   963  O  O   . LYS A 1 119 ? -23.321 -9.29   44.286  1    51.01  ? 289 LYS D O   1 
ATOM   964  C  CB  . LYS A 1 119 ? -21.55  -8.923  46.822  1    53.59  ? 289 LYS D CB  1 
ATOM   965  C  CG  . LYS A 1 119 ? -20.861 -8.303  45.606  1    67.62  ? 289 LYS D CG  1 
ATOM   966  C  CD  . LYS A 1 119 ? -19.398 -7.938  45.833  1    71.76  ? 289 LYS D CD  1 
ATOM   967  C  CE  . LYS A 1 119 ? -18.546 -9.17   45.933  1    74.09  ? 289 LYS D CE  1 
ATOM   968  N  NZ  . LYS A 1 119 ? -17.105 -8.899  45.966  1    78.57  ? 289 LYS D NZ  1 
ATOM   969  N  N   . GLN A 1 120 ? -23.429 -11.165 45.543  1    45.29  ? 290 GLN D N   1 
ATOM   970  C  CA  . GLN A 1 120 ? -23.73  -12.006 44.399  1    44.65  ? 290 GLN D CA  1 
ATOM   971  C  C   . GLN A 1 120 ? -25.083 -11.648 43.814  1    40.22  ? 290 GLN D C   1 
ATOM   972  O  O   . GLN A 1 120 ? -25.22  -11.486 42.599  1    41.42  ? 290 GLN D O   1 
ATOM   973  C  CB  . GLN A 1 120 ? -23.671 -13.473 44.785  1    47.84  ? 290 GLN D CB  1 
ATOM   974  C  CG  . GLN A 1 120 ? -22.245 -13.918 45.076  1    49.95  ? 290 GLN D CG  1 
ATOM   975  C  CD  . GLN A 1 120 ? -22.209 -15.328 45.601  1    51.11  ? 290 GLN D CD  1 
ATOM   976  O  OE1 . GLN A 1 120 ? -22.782 -15.637 46.655  1    54.87  ? 290 GLN D OE1 1 
ATOM   977  N  NE2 . GLN A 1 120 ? -21.588 -16.196 44.823  1    48.2   ? 290 GLN D NE2 1 
ATOM   978  N  N   . VAL A 1 121 ? -26.064 -11.502 44.693  1    38.09  ? 291 VAL D N   1 
ATOM   979  C  CA  . VAL A 1 121 ? -27.384 -11.126 44.232  1    37.4   ? 291 VAL D CA  1 
ATOM   980  C  C   . VAL A 1 121 ? -27.326 -9.792  43.469  1    38.01  ? 291 VAL D C   1 
ATOM   981  O  O   . VAL A 1 121 ? -27.894 -9.686  42.391  1    40.26  ? 291 VAL D O   1 
ATOM   982  C  CB  . VAL A 1 121 ? -28.42  -11.171 45.374  1    38.4   ? 291 VAL D CB  1 
ATOM   983  C  CG1 . VAL A 1 121 ? -29.769 -10.619 44.929  1    36.51  ? 291 VAL D CG1 1 
ATOM   984  C  CG2 . VAL A 1 121 ? -28.564 -12.58  45.955  1    34.25  ? 291 VAL D CG2 1 
ATOM   985  N  N   . LEU A 1 122 ? -26.612 -8.77   43.96   1    40.82  ? 292 LEU D N   1 
ATOM   986  C  CA  . LEU A 1 122 ? -26.655 -7.476  43.273  1    42.82  ? 292 LEU D CA  1 
ATOM   987  C  C   . LEU A 1 122 ? -25.859 -7.486  41.963  1    45.57  ? 292 LEU D C   1 
ATOM   988  O  O   . LEU A 1 122 ? -26.227 -6.811  40.994  1    46.16  ? 292 LEU D O   1 
ATOM   989  C  CB  . LEU A 1 122 ? -26.182 -6.373  44.209  1    42.4   ? 292 LEU D CB  1 
ATOM   990  C  CG  . LEU A 1 122 ? -27.134 -6.094  45.378  1    48.26  ? 292 LEU D CG  1 
ATOM   991  C  CD1 . LEU A 1 122 ? -26.477 -5.163  46.386  1    46.27  ? 292 LEU D CD1 1 
ATOM   992  C  CD2 . LEU A 1 122 ? -28.498 -5.571  44.904  1    44.89  ? 292 LEU D CD2 1 
ATOM   993  N  N   . ARG A 1 123 ? -24.76  -8.25   41.951  1    42.76  ? 293 ARG D N   1 
ATOM   994  C  CA  . ARG A 1 123 ? -23.924 -8.375  40.778  1    40.34  ? 293 ARG D CA  1 
ATOM   995  C  C   . ARG A 1 123 ? -24.681 -9.129  39.689  1    40.08  ? 293 ARG D C   1 
ATOM   996  O  O   . ARG A 1 123 ? -24.672 -8.7    38.541  1    39.68  ? 293 ARG D O   1 
ATOM   997  C  CB  . ARG A 1 123 ? -22.56  -8.949  41.156  1    42.73  ? 293 ARG D CB  1 
ATOM   998  C  CG  . ARG A 1 123 ? -21.6   -7.882  41.662  1    45.03  ? 293 ARG D CG  1 
ATOM   999  C  CD  . ARG A 1 123 ? -20.218 -8.472  41.735  1    63     ? 293 ARG D CD  1 
ATOM   1000 N  NE  . ARG A 1 123 ? -19.307 -7.509  42.363  1    92.21  ? 293 ARG D NE  1 
ATOM   1001 C  CZ  . ARG A 1 123 ? -18.061 -7.756  42.785  1    102.42 ? 293 ARG D CZ  1 
ATOM   1002 N  NH1 . ARG A 1 123 ? -17.373 -6.818  43.417  1    85.19  ? 293 ARG D NH1 1 
ATOM   1003 N  NH2 . ARG A 1 123 ? -17.514 -8.946  42.595  1    118.38 ? 293 ARG D NH2 1 
ATOM   1004 N  N   . MET A 1 124 ? -25.37  -10.215 40.068  1    39.59  ? 294 MET D N   1 
ATOM   1005 C  CA  . MET A 1 124 ? -26.212 -10.962 39.144  1    37.13  ? 294 MET D CA  1 
ATOM   1006 C  C   . MET A 1 124 ? -27.344 -10.085 38.634  1    35.64  ? 294 MET D C   1 
ATOM   1007 O  O   . MET A 1 124 ? -27.677 -10.179 37.46   1    38.09  ? 294 MET D O   1 
ATOM   1008 C  CB  . MET A 1 124 ? -26.835 -12.209 39.774  1    36.29  ? 294 MET D CB  1 
ATOM   1009 C  CG  . MET A 1 124 ? -27.682 -13.017 38.801  1    34.02  ? 294 MET D CG  1 
ATOM   1010 S  SD  . MET A 1 124 ? -26.752 -13.789 37.458  1    39.18  ? 294 MET D SD  1 
ATOM   1011 C  CE  . MET A 1 124 ? -25.964 -15.153 38.336  1    39.92  ? 294 MET D CE  1 
ATOM   1012 N  N   . GLU A 1 125 ? -27.958 -9.287  39.518  1    35.2   ? 295 GLU D N   1 
ATOM   1013 C  CA  . GLU A 1 125 ? -28.896 -8.264  39.071  1    36.17  ? 295 GLU D CA  1 
ATOM   1014 C  C   . GLU A 1 125 ? -28.318 -7.459  37.898  1    39.01  ? 295 GLU D C   1 
ATOM   1015 O  O   . GLU A 1 125 ? -28.975 -7.299  36.874  1    40.07  ? 295 GLU D O   1 
ATOM   1016 C  CB  . GLU A 1 125 ? -29.295 -7.289  40.176  1    34.11  ? 295 GLU D CB  1 
ATOM   1017 C  CG  . GLU A 1 125 ? -30.368 -6.299  39.74   1    32.65  ? 295 GLU D CG  1 
ATOM   1018 C  CD  . GLU A 1 125 ? -30.756 -5.242  40.761  1    39.74  ? 295 GLU D CD  1 
ATOM   1019 O  OE1 . GLU A 1 125 ? -29.89  -4.383  41.138  1    46.66  ? 295 GLU D OE1 1 
ATOM   1020 O  OE2 . GLU A 1 125 ? -31.957 -5.244  41.145  1    40.12  ? 295 GLU D OE2 1 
ATOM   1021 N  N   . HIS A 1 126 ? -27.093 -6.954  38.045  1    38.08  ? 296 HIS D N   1 
ATOM   1022 C  CA  . HIS A 1 126 ? -26.547 -6.084  37.018  1    41.27  ? 296 HIS D CA  1 
ATOM   1023 C  C   . HIS A 1 126 ? -26.356 -6.917  35.743  1    41.38  ? 296 HIS D C   1 
ATOM   1024 O  O   . HIS A 1 126 ? -26.691 -6.47   34.633  1    37.63  ? 296 HIS D O   1 
ATOM   1025 C  CB  . HIS A 1 126 ? -25.33  -5.292  37.539  1    40.06  ? 296 HIS D CB  1 
ATOM   1026 C  CG  . HIS A 1 126 ? -24.972 -4.078  36.719  1    51.56  ? 296 HIS D CG  1 
ATOM   1027 N  ND1 . HIS A 1 126 ? -23.932 -3.224  37.05   1    55.44  ? 296 HIS D ND1 1 
ATOM   1028 C  CD2 . HIS A 1 126 ? -25.487 -3.588  35.548  1    51.94  ? 296 HIS D CD2 1 
ATOM   1029 C  CE1 . HIS A 1 126 ? -23.841 -2.261  36.126  1    55.36  ? 296 HIS D CE1 1 
ATOM   1030 N  NE2 . HIS A 1 126 ? -24.789 -2.446  35.218  1    52.51  ? 296 HIS D NE2 1 
ATOM   1031 N  N   . LEU A 1 127 ? -25.822 -8.138  35.918  1    40.14  ? 297 LEU D N   1 
ATOM   1032 C  CA  . LEU A 1 127 ? -25.518 -8.985  34.776  1    38.09  ? 297 LEU D CA  1 
ATOM   1033 C  C   . LEU A 1 127 ? -26.806 -9.282  34.015  1    36.58  ? 297 LEU D C   1 
ATOM   1034 O  O   . LEU A 1 127 ? -26.837 -9.146  32.805  1    42.1   ? 297 LEU D O   1 
ATOM   1035 C  CB  . LEU A 1 127 ? -24.773 -10.261 35.146  1    37.03  ? 297 LEU D CB  1 
ATOM   1036 C  CG  . LEU A 1 127 ? -24.434 -11.182 33.963  1    38.03  ? 297 LEU D CG  1 
ATOM   1037 C  CD1 . LEU A 1 127 ? -23.376 -10.617 33.014  1    34.64  ? 297 LEU D CD1 1 
ATOM   1038 C  CD2 . LEU A 1 127 ? -23.991 -12.564 34.446  1    37.59  ? 297 LEU D CD2 1 
ATOM   1039 N  N   . VAL A 1 128 ? -27.874 -9.63   34.724  1    32.51  ? 298 VAL D N   1 
ATOM   1040 C  CA  . VAL A 1 128 ? -29.122 -9.913  34.044  1    33.1   ? 298 VAL D CA  1 
ATOM   1041 C  C   . VAL A 1 128 ? -29.614 -8.701  33.254  1    37.05  ? 298 VAL D C   1 
ATOM   1042 O  O   . VAL A 1 128 ? -30.119 -8.864  32.134  1    46.68  ? 298 VAL D O   1 
ATOM   1043 C  CB  . VAL A 1 128 ? -30.205 -10.458 34.975  1    33.09  ? 298 VAL D CB  1 
ATOM   1044 C  CG1 . VAL A 1 128 ? -31.538 -10.511 34.249  1    30.55  ? 298 VAL D CG1 1 
ATOM   1045 C  CG2 . VAL A 1 128 ? -29.836 -11.848 35.494  1    32.12  ? 298 VAL D CG2 1 
ATOM   1046 N  N   . LEU A 1 129 ? -29.439 -7.493  33.806  1    35.79  ? 299 LEU D N   1 
ATOM   1047 C  CA  . LEU A 1 129 ? -29.878 -6.271  33.143  1    35.18  ? 299 LEU D CA  1 
ATOM   1048 C  C   . LEU A 1 129 ? -29.1   -6.071  31.844  1    39.92  ? 299 LEU D C   1 
ATOM   1049 O  O   . LEU A 1 129 ? -29.682 -5.671  30.833  1    39.15  ? 299 LEU D O   1 
ATOM   1050 C  CB  . LEU A 1 129 ? -29.752 -5.056  34.062  1    35.56  ? 299 LEU D CB  1 
ATOM   1051 C  CG  . LEU A 1 129 ? -30.908 -4.825  35.044  1    39.96  ? 299 LEU D CG  1 
ATOM   1052 C  CD1 . LEU A 1 129 ? -30.54  -3.699  36.001  1    38.7   ? 299 LEU D CD1 1 
ATOM   1053 C  CD2 . LEU A 1 129 ? -32.247 -4.536  34.338  1    35.48  ? 299 LEU D CD2 1 
ATOM   1054 N  N   . LYS A 1 130 ? -27.789 -6.379  31.879  1    39.95  ? 300 LYS D N   1 
ATOM   1055 C  CA  . LYS A 1 130 ? -26.921 -6.193  30.728  1    39.3   ? 300 LYS D CA  1 
ATOM   1056 C  C   . LYS A 1 130 ? -27.305 -7.169  29.617  1    40.43  ? 300 LYS D C   1 
ATOM   1057 O  O   . LYS A 1 130 ? -27.42  -6.773  28.447  1    38.99  ? 300 LYS D O   1 
ATOM   1058 C  CB  . LYS A 1 130 ? -25.445 -6.35   31.106  1    41.05  ? 300 LYS D CB  1 
ATOM   1059 C  CG  . LYS A 1 130 ? -24.805 -5.161  31.803  1    44.41  ? 300 LYS D CG  1 
ATOM   1060 C  CD  . LYS A 1 130 ? -23.295 -5.306  31.991  1    54.08  ? 300 LYS D CD  1 
ATOM   1061 C  CE  . LYS A 1 130 ? -22.667 -4.322  32.936  1    64.18  ? 300 LYS D CE  1 
ATOM   1062 N  NZ  . LYS A 1 130 ? -21.629 -4.856  33.829  1    70.97  ? 300 LYS D NZ  1 
ATOM   1063 N  N   . VAL A 1 131 ? -27.506 -8.438  30.001  1    36.99  ? 301 VAL D N   1 
ATOM   1064 C  CA  . VAL A 1 131 ? -27.813 -9.487  29.047  1    39.38  ? 301 VAL D CA  1 
ATOM   1065 C  C   . VAL A 1 131 ? -29.165 -9.246  28.382  1    41.45  ? 301 VAL D C   1 
ATOM   1066 O  O   . VAL A 1 131 ? -29.272 -9.414  27.171  1    42.41  ? 301 VAL D O   1 
ATOM   1067 C  CB  . VAL A 1 131 ? -27.754 -10.855 29.732  1    43.76  ? 301 VAL D CB  1 
ATOM   1068 C  CG1 . VAL A 1 131 ? -28.556 -11.896 28.975  1    39.36  ? 301 VAL D CG1 1 
ATOM   1069 C  CG2 . VAL A 1 131 ? -26.31  -11.303 29.921  1    44.92  ? 301 VAL D CG2 1 
ATOM   1070 N  N   . LEU A 1 132 ? -30.176 -8.817  29.151  1    39.28  ? 302 LEU D N   1 
ATOM   1071 C  CA  . LEU A 1 132 ? -31.475 -8.468  28.578  1    38.15  ? 302 LEU D CA  1 
ATOM   1072 C  C   . LEU A 1 132 ? -31.496 -7.057  27.995  1    40.32  ? 302 LEU D C   1 
ATOM   1073 O  O   . LEU A 1 132 ? -32.559 -6.615  27.564  1    39.35  ? 302 LEU D O   1 
ATOM   1074 C  CB  . LEU A 1 132 ? -32.558 -8.522  29.649  1    37.28  ? 302 LEU D CB  1 
ATOM   1075 C  CG  . LEU A 1 132 ? -32.753 -9.866  30.342  1    41     ? 302 LEU D CG  1 
ATOM   1076 C  CD1 . LEU A 1 132 ? -33.928 -9.76   31.304  1    41.1   ? 302 LEU D CD1 1 
ATOM   1077 C  CD2 . LEU A 1 132 ? -32.948 -10.972 29.318  1    37.89  ? 302 LEU D CD2 1 
ATOM   1078 N  N   . ALA A 1 133 ? -30.386 -6.307  28.095  1    38.91  ? 303 ALA D N   1 
ATOM   1079 C  CA  . ALA A 1 133 ? -30.339 -4.926  27.607  1    40.26  ? 303 ALA D CA  1 
ATOM   1080 C  C   . ALA A 1 133 ? -31.481 -4.056  28.148  1    39.55  ? 303 ALA D C   1 
ATOM   1081 O  O   . ALA A 1 133 ? -31.994 -3.214  27.418  1    38.11  ? 303 ALA D O   1 
ATOM   1082 C  CB  . ALA A 1 133 ? -30.355 -4.922  26.099  1    37.33  ? 303 ALA D CB  1 
ATOM   1083 N  N   . PHE A 1 134 ? -31.901 -4.291  29.39   1    39.01  ? 304 PHE D N   1 
ATOM   1084 C  CA  . PHE A 1 134 ? -32.977 -3.507  30.061  1    39.48  ? 304 PHE D CA  1 
ATOM   1085 C  C   . PHE A 1 134 ? -34.303 -3.67   29.35   1    39.35  ? 304 PHE D C   1 
ATOM   1086 O  O   . PHE A 1 134 ? -35.194 -2.878  29.61   1    44.77  ? 304 PHE D O   1 
ATOM   1087 C  CB  . PHE A 1 134 ? -32.624 -2.024  30.203  1    43.15  ? 304 PHE D CB  1 
ATOM   1088 C  CG  . PHE A 1 134 ? -31.81  -1.638  31.429  1    47.97  ? 304 PHE D CG  1 
ATOM   1089 C  CD1 . PHE A 1 134 ? -30.423 -1.699  31.412  1    44.85  ? 304 PHE D CD1 1 
ATOM   1090 C  CD2 . PHE A 1 134 ? -32.435 -1.189  32.586  1    44.99  ? 304 PHE D CD2 1 
ATOM   1091 C  CE1 . PHE A 1 134 ? -29.686 -1.335  32.524  1    45.83  ? 304 PHE D CE1 1 
ATOM   1092 C  CE2 . PHE A 1 134 ? -31.691 -0.824  33.693  1    45.51  ? 304 PHE D CE2 1 
ATOM   1093 C  CZ  . PHE A 1 134 ? -30.321 -0.898  33.659  1    43.81  ? 304 PHE D CZ  1 
ATOM   1094 N  N   . ASP A 1 135 ? -34.441 -4.659  28.477  1    44.37  ? 305 ASP D N   1 
ATOM   1095 C  CA  . ASP A 1 135 ? -35.767 -4.914  27.849  1    44.72  ? 305 ASP D CA  1 
ATOM   1096 C  C   . ASP A 1 135 ? -36.564 -5.751  28.842  1    41.9   ? 305 ASP D C   1 
ATOM   1097 O  O   . ASP A 1 135 ? -36.522 -6.984  28.742  1    41.86  ? 305 ASP D O   1 
ATOM   1098 C  CB  . ASP A 1 135 ? -35.644 -5.481  26.445  1    52.68  ? 305 ASP D CB  1 
ATOM   1099 C  CG  . ASP A 1 135 ? -34.832 -4.637  25.475  1    72.4   ? 305 ASP D CG  1 
ATOM   1100 O  OD1 . ASP A 1 135 ? -34.9   -3.398  25.578  1    72.03  ? 305 ASP D OD1 1 
ATOM   1101 O  OD2 . ASP A 1 135 ? -34.137 -5.228  24.626  1    93.12  ? 305 ASP D OD2 1 
ATOM   1102 N  N   . LEU A 1 136 ? -37.274 -5.146  29.735  1    37.02  ? 306 LEU D N   1 
ATOM   1103 C  CA  . LEU A 1 136 ? -37.965 -5.876  30.818  1    35.16  ? 306 LEU D CA  1 
ATOM   1104 C  C   . LEU A 1 136 ? -39.491 -5.799  30.703  1    37.35  ? 306 LEU D C   1 
ATOM   1105 O  O   . LEU A 1 136 ? -40.157 -6.526  31.446  1    38.43  ? 306 LEU D O   1 
ATOM   1106 C  CB  . LEU A 1 136 ? -37.481 -5.213  32.103  1    36.62  ? 306 LEU D CB  1 
ATOM   1107 C  CG  . LEU A 1 136 ? -36.076 -5.555  32.605  1    39.64  ? 306 LEU D CG  1 
ATOM   1108 C  CD1 . LEU A 1 136 ? -36.087 -5.557  34.118  1    42.41  ? 306 LEU D CD1 1 
ATOM   1109 C  CD2 . LEU A 1 136 ? -35.588 -6.884  32.096  1    35.03  ? 306 LEU D CD2 1 
ATOM   1110 N  N   . ALA A 1 137 ? -40.029 -4.907  29.849  1    35.06  ? 307 ALA D N   1 
ATOM   1111 C  CA  . ALA A 1 137 ? -41.488 -4.837  29.807  1    37.27  ? 307 ALA D CA  1 
ATOM   1112 C  C   . ALA A 1 137 ? -42.052 -5.916  28.873  1    40.39  ? 307 ALA D C   1 
ATOM   1113 O  O   . ALA A 1 137 ? -42.499 -5.599  27.779  1    42.84  ? 307 ALA D O   1 
ATOM   1114 C  CB  . ALA A 1 137 ? -41.971 -3.447  29.449  1    34.19  ? 307 ALA D CB  1 
ATOM   1115 N  N   . ALA A 1 138 ? -42.017 -7.192  29.302  1    36.75  ? 308 ALA D N   1 
ATOM   1116 C  CA  . ALA A 1 138 ? -42.333 -8.315  28.431  1    35.64  ? 308 ALA D CA  1 
ATOM   1117 C  C   . ALA A 1 138 ? -43.816 -8.593  28.534  1    37.91  ? 308 ALA D C   1 
ATOM   1118 O  O   . ALA A 1 138 ? -44.377 -8.568  29.615  1    42.89  ? 308 ALA D O   1 
ATOM   1119 C  CB  . ALA A 1 138 ? -41.584 -9.573  28.828  1    32.72  ? 308 ALA D CB  1 
ATOM   1120 N  N   . PRO A 1 139 ? -44.5   -8.89   27.424  1    39.16  ? 309 PRO D N   1 
ATOM   1121 C  CA  . PRO A 1 139 ? -45.887 -9.336  27.522  1    42.43  ? 309 PRO D CA  1 
ATOM   1122 C  C   . PRO A 1 139 ? -45.936 -10.729 28.157  1    43.07  ? 309 PRO D C   1 
ATOM   1123 O  O   . PRO A 1 139 ? -45.117 -11.597 27.837  1    44.24  ? 309 PRO D O   1 
ATOM   1124 C  CB  . PRO A 1 139 ? -46.34  -9.314  26.047  1    43.91  ? 309 PRO D CB  1 
ATOM   1125 C  CG  . PRO A 1 139 ? -45.299 -8.488  25.317  1    38.86  ? 309 PRO D CG  1 
ATOM   1126 C  CD  . PRO A 1 139 ? -43.999 -8.779  26.046  1    39.2   ? 309 PRO D CD  1 
ATOM   1127 N  N   . THR A 1 140 ? -46.874 -10.908 29.092  1    39.97  ? 310 THR D N   1 
ATOM   1128 C  CA  . THR A 1 140 ? -47.038 -12.155 29.825  1    38.99  ? 310 THR D CA  1 
ATOM   1129 C  C   . THR A 1 140 ? -48.346 -12.824 29.404  1    41.3   ? 310 THR D C   1 
ATOM   1130 O  O   . THR A 1 140 ? -49.244 -12.181 28.857  1    39.48  ? 310 THR D O   1 
ATOM   1131 C  CB  . THR A 1 140 ? -47.084 -11.915 31.337  1    36.41  ? 310 THR D CB  1 
ATOM   1132 O  OG1 . THR A 1 140 ? -48.21  -11.062 31.566  1    40.51  ? 310 THR D OG1 1 
ATOM   1133 C  CG2 . THR A 1 140 ? -45.813 -11.302 31.883  1    33.05  ? 310 THR D CG2 1 
ATOM   1134 N  N   . ILE A 1 141 ? -48.471 -14.104 29.768  1    42.64  ? 311 ILE D N   1 
ATOM   1135 C  CA  . ILE A 1 141 ? -49.741 -14.802 29.673  1    42.98  ? 311 ILE D CA  1 
ATOM   1136 C  C   . ILE A 1 141 ? -50.82  -13.949 30.338  1    50.42  ? 311 ILE D C   1 
ATOM   1137 O  O   . ILE A 1 141 ? -51.866 -13.709 29.737  1    60.02  ? 311 ILE D O   1 
ATOM   1138 C  CB  . ILE A 1 141 ? -49.614 -16.195 30.298  1    38.64  ? 311 ILE D CB  1 
ATOM   1139 C  CG1 . ILE A 1 141 ? -48.773 -17.121 29.409  1    37.63  ? 311 ILE D CG1 1 
ATOM   1140 C  CG2 . ILE A 1 141 ? -50.993 -16.757 30.608  1    37.83  ? 311 ILE D CG2 1 
ATOM   1141 C  CD1 . ILE A 1 141 ? -48.296 -18.396 30.09   1    36.86  ? 311 ILE D CD1 1 
ATOM   1142 N  N   . ASN A 1 142 ? -50.531 -13.415 31.535  1    49.07  ? 312 ASN D N   1 
ATOM   1143 C  CA  . ASN A 1 142 ? -51.521 -12.655 32.288  1    51.27  ? 312 ASN D CA  1 
ATOM   1144 C  C   . ASN A 1 142 ? -51.966 -11.401 31.54   1    48.2   ? 312 ASN D C   1 
ATOM   1145 O  O   . ASN A 1 142 ? -53.108 -10.974 31.66   1    51.56  ? 312 ASN D O   1 
ATOM   1146 C  CB  . ASN A 1 142 ? -51.061 -12.276 33.694  1    53.05  ? 312 ASN D CB  1 
ATOM   1147 C  CG  . ASN A 1 142 ? -51.208 -13.403 34.682  1    58.73  ? 312 ASN D CG  1 
ATOM   1148 O  OD1 . ASN A 1 142 ? -51.211 -14.587 34.317  1    73.09  ? 312 ASN D OD1 1 
ATOM   1149 N  ND2 . ASN A 1 142 ? -51.296 -13.048 35.947  1    61.44  ? 312 ASN D ND2 1 
ATOM   1150 N  N   . GLN A 1 143 ? -51.066 -10.778 30.79   1    47.72  ? 313 GLN D N   1 
ATOM   1151 C  CA  . GLN A 1 143 ? -51.485 -9.562  30.114  1    46.79  ? 313 GLN D CA  1 
ATOM   1152 C  C   . GLN A 1 143 ? -52.472 -9.887  29.005  1    46.34  ? 313 GLN D C   1 
ATOM   1153 O  O   . GLN A 1 143 ? -53.207 -8.992  28.602  1    50.8   ? 313 GLN D O   1 
ATOM   1154 C  CB  . GLN A 1 143 ? -50.308 -8.79   29.536  1    41.82  ? 313 GLN D CB  1 
ATOM   1155 C  CG  . GLN A 1 143 ? -49.533 -8.048  30.609  1    41.07  ? 313 GLN D CG  1 
ATOM   1156 C  CD  . GLN A 1 143 ? -48.258 -7.442  30.063  1    41.78  ? 313 GLN D CD  1 
ATOM   1157 O  OE1 . GLN A 1 143 ? -48.268 -6.678  29.087  1    43.14  ? 313 GLN D OE1 1 
ATOM   1158 N  NE2 . GLN A 1 143 ? -47.142 -7.788  30.689  1    38.61  ? 313 GLN D NE2 1 
ATOM   1159 N  N   . PHE A 1 144 ? -52.428 -11.124 28.479  1    43.14  ? 314 PHE D N   1 
ATOM   1160 C  CA  . PHE A 1 144 ? -53.336 -11.518 27.423  1    45.26  ? 314 PHE D CA  1 
ATOM   1161 C  C   . PHE A 1 144 ? -54.636 -12.008 28.047  1    49.13  ? 314 PHE D C   1 
ATOM   1162 O  O   . PHE A 1 144 ? -55.711 -11.756 27.495  1    50.44  ? 314 PHE D O   1 
ATOM   1163 C  CB  . PHE A 1 144 ? -52.757 -12.534 26.442  1    47.19  ? 314 PHE D CB  1 
ATOM   1164 C  CG  . PHE A 1 144 ? -51.773 -11.904 25.479  1    47.9   ? 314 PHE D CG  1 
ATOM   1165 C  CD1 . PHE A 1 144 ? -52.231 -11.129 24.413  1    49.46  ? 314 PHE D CD1 1 
ATOM   1166 C  CD2 . PHE A 1 144 ? -50.397 -12.061 25.661  1    44.83  ? 314 PHE D CD2 1 
ATOM   1167 C  CE1 . PHE A 1 144 ? -51.32  -10.534 23.539  1    47.41  ? 314 PHE D CE1 1 
ATOM   1168 C  CE2 . PHE A 1 144 ? -49.492 -11.462 24.791  1    43.02  ? 314 PHE D CE2 1 
ATOM   1169 C  CZ  . PHE A 1 144 ? -49.955 -10.715 23.724  1    44.4   ? 314 PHE D CZ  1 
ATOM   1170 N  N   . LEU A 1 145 ? -54.532 -12.661 29.217  1    49.1   ? 315 LEU D N   1 
ATOM   1171 C  CA  . LEU A 1 145 ? -55.708 -13.223 29.867  1    51.04  ? 315 LEU D CA  1 
ATOM   1172 C  C   . LEU A 1 145 ? -56.657 -12.123 30.326  1    52.17  ? 315 LEU D C   1 
ATOM   1173 O  O   . LEU A 1 145 ? -57.858 -12.205 30.051  1    53.7   ? 315 LEU D O   1 
ATOM   1174 C  CB  . LEU A 1 145 ? -55.312 -14.101 31.042  1    53.35  ? 315 LEU D CB  1 
ATOM   1175 C  CG  . LEU A 1 145 ? -54.851 -15.522 30.727  1    52.45  ? 315 LEU D CG  1 
ATOM   1176 C  CD1 . LEU A 1 145 ? -54.644 -16.246 32.053  1    50.57  ? 315 LEU D CD1 1 
ATOM   1177 C  CD2 . LEU A 1 145 ? -55.864 -16.214 29.86   1    51.91  ? 315 LEU D CD2 1 
ATOM   1178 N  N   . THR A 1 146 ? -56.12  -11.104 31.018  1    48.41  ? 316 THR D N   1 
ATOM   1179 C  CA  . THR A 1 146 ? -56.989 -10.061 31.544  1    52.09  ? 316 THR D CA  1 
ATOM   1180 C  C   . THR A 1 146 ? -57.743 -9.422  30.387  1    57.83  ? 316 THR D C   1 
ATOM   1181 O  O   . THR A 1 146 ? -58.873 -8.979  30.581  1    67.76  ? 316 THR D O   1 
ATOM   1182 C  CB  . THR A 1 146 ? -56.268 -8.995  32.361  1    49.76  ? 316 THR D CB  1 
ATOM   1183 O  OG1 . THR A 1 146 ? -55.283 -8.516  31.457  1    51.26  ? 316 THR D OG1 1 
ATOM   1184 C  CG2 . THR A 1 146 ? -55.667 -9.508  33.657  1    46.59  ? 316 THR D CG2 1 
ATOM   1185 N  N   . GLN A 1 147 ? -57.117 -9.395  29.199  1    57.12  ? 317 GLN D N   1 
ATOM   1186 C  CA  . GLN A 1 147 ? -57.726 -8.793  28.02   1    56.88  ? 317 GLN D CA  1 
ATOM   1187 C  C   . GLN A 1 147 ? -58.819 -9.706  27.481  1    59.5   ? 317 GLN D C   1 
ATOM   1188 O  O   . GLN A 1 147 ? -59.854 -9.217  27.037  1    62.76  ? 317 GLN D O   1 
ATOM   1189 C  CB  . GLN A 1 147 ? -56.741 -8.471  26.898  1    56.6   ? 317 GLN D CB  1 
ATOM   1190 C  CG  . GLN A 1 147 ? -56.019 -7.138  27.067  1    58.47  ? 317 GLN D CG  1 
ATOM   1191 C  CD  . GLN A 1 147 ? -55.092 -6.775  25.921  1    59.36  ? 317 GLN D CD  1 
ATOM   1192 O  OE1 . GLN A 1 147 ? -55.485 -6.664  24.751  1    60.78  ? 317 GLN D OE1 1 
ATOM   1193 N  NE2 . GLN A 1 147 ? -53.837 -6.547  26.263  1    60.49  ? 317 GLN D NE2 1 
ATOM   1194 N  N   . TYR A 1 148 ? -58.565 -11.025 27.501  1    60.22  ? 318 TYR D N   1 
ATOM   1195 C  CA  . TYR A 1 148 ? -59.48  -12.009 26.933  1    59.57  ? 318 TYR D CA  1 
ATOM   1196 C  C   . TYR A 1 148 ? -60.734 -12.1   27.807  1    61.69  ? 318 TYR D C   1 
ATOM   1197 O  O   . TYR A 1 148 ? -61.822 -12.406 27.314  1    63.15  ? 318 TYR D O   1 
ATOM   1198 C  CB  . TYR A 1 148 ? -58.817 -13.381 26.755  1    56.4   ? 318 TYR D CB  1 
ATOM   1199 C  CG  . TYR A 1 148 ? -57.649 -13.525 25.786  1    53.09  ? 318 TYR D CG  1 
ATOM   1200 C  CD1 . TYR A 1 148 ? -57.33  -12.553 24.842  1    50.19  ? 318 TYR D CD1 1 
ATOM   1201 C  CD2 . TYR A 1 148 ? -56.853 -14.662 25.822  1    52.41  ? 318 TYR D CD2 1 
ATOM   1202 C  CE1 . TYR A 1 148 ? -56.252 -12.711 23.98   1    49.05  ? 318 TYR D CE1 1 
ATOM   1203 C  CE2 . TYR A 1 148 ? -55.786 -14.835 24.951  1    50.66  ? 318 TYR D CE2 1 
ATOM   1204 C  CZ  . TYR A 1 148 ? -55.468 -13.856 24.027  1    50.01  ? 318 TYR D CZ  1 
ATOM   1205 O  OH  . TYR A 1 148 ? -54.374 -14.044 23.193  1    52.18  ? 318 TYR D OH  1 
ATOM   1206 N  N   . PHE A 1 149 ? -60.57  -11.789 29.099  1    61.4   ? 319 PHE D N   1 
ATOM   1207 C  CA  . PHE A 1 149 ? -61.637 -11.857 30.084  1    63.33  ? 319 PHE D CA  1 
ATOM   1208 C  C   . PHE A 1 149 ? -62.748 -10.866 29.756  1    63.89  ? 319 PHE D C   1 
ATOM   1209 O  O   . PHE A 1 149 ? -63.913 -11.16  30.023  1    68.04  ? 319 PHE D O   1 
ATOM   1210 C  CB  . PHE A 1 149 ? -61.11  -11.546 31.483  1    61.98  ? 319 PHE D CB  1 
ATOM   1211 C  CG  . PHE A 1 149 ? -60.213 -12.606 32.098  1    61.49  ? 319 PHE D CG  1 
ATOM   1212 C  CD1 . PHE A 1 149 ? -60.079 -13.867 31.522  1    63.06  ? 319 PHE D CD1 1 
ATOM   1213 C  CD2 . PHE A 1 149 ? -59.531 -12.342 33.283  1    60.86  ? 319 PHE D CD2 1 
ATOM   1214 C  CE1 . PHE A 1 149 ? -59.26  -14.819 32.107  1    63.17  ? 319 PHE D CE1 1 
ATOM   1215 C  CE2 . PHE A 1 149 ? -58.726 -13.297 33.879  1    59.23  ? 319 PHE D CE2 1 
ATOM   1216 C  CZ  . PHE A 1 149 ? -58.584 -14.53  33.285  1    63.02  ? 319 PHE D CZ  1 
ATOM   1217 N  N   . LEU A 1 150 ? -62.384 -9.708  29.195  1    62.29  ? 320 LEU D N   1 
ATOM   1218 C  CA  . LEU A 1 150 ? -63.331 -8.64   28.884  1    66.93  ? 320 LEU D CA  1 
ATOM   1219 C  C   . LEU A 1 150 ? -64.387 -9.092  27.861  1    67.9   ? 320 LEU D C   1 
ATOM   1220 O  O   . LEU A 1 150 ? -65.423 -8.445  27.699  1    68.95  ? 320 LEU D O   1 
ATOM   1221 C  CB  . LEU A 1 150 ? -62.579 -7.384  28.428  1    64.14  ? 320 LEU D CB  1 
ATOM   1222 C  CG  . LEU A 1 150 ? -61.618 -6.736  29.439  1    61.47  ? 320 LEU D CG  1 
ATOM   1223 C  CD1 . LEU A 1 150 ? -60.697 -5.714  28.748  1    55.12  ? 320 LEU D CD1 1 
ATOM   1224 C  CD2 . LEU A 1 150 ? -62.319 -6.121  30.666  1    56.95  ? 320 LEU D CD2 1 
ATOM   1225 N  N   . HIS A 1 151 ? -64.119 -10.196 27.154  1    65.68  ? 321 HIS D N   1 
ATOM   1226 C  CA  . HIS A 1 151 ? -65.049 -10.719 26.17   1    66.05  ? 321 HIS D CA  1 
ATOM   1227 C  C   . HIS A 1 151 ? -66.114 -11.598 26.828  1    70     ? 321 HIS D C   1 
ATOM   1228 O  O   . HIS A 1 151 ? -67.096 -11.975 26.176  1    70.09  ? 321 HIS D O   1 
ATOM   1229 C  CB  . HIS A 1 151 ? -64.293 -11.368 25.011  1    65.07  ? 321 HIS D CB  1 
ATOM   1230 C  CG  . HIS A 1 151 ? -63.581 -10.375 24.166  1    65.62  ? 321 HIS D CG  1 
ATOM   1231 N  ND1 . HIS A 1 151 ? -63.834 -10.239 22.817  1    66.68  ? 321 HIS D ND1 1 
ATOM   1232 C  CD2 . HIS A 1 151 ? -62.668 -9.435  24.487  1    62.82  ? 321 HIS D CD2 1 
ATOM   1233 C  CE1 . HIS A 1 151 ? -63.064 -9.266  22.339  1    67.69  ? 321 HIS D CE1 1 
ATOM   1234 N  NE2 . HIS A 1 151 ? -62.345 -8.767  23.335  1    63.9   ? 321 HIS D NE2 1 
ATOM   1235 N  N   . GLN A 1 152 ? -65.94  -11.887 28.129  1    70.17  ? 322 GLN D N   1 
ATOM   1236 C  CA  . GLN A 1 152 ? -66.947 -12.617 28.881  1    72.69  ? 322 GLN D CA  1 
ATOM   1237 C  C   . GLN A 1 152 ? -68.205 -11.771 29.026  1    79.64  ? 322 GLN D C   1 
ATOM   1238 O  O   . GLN A 1 152 ? -68.133 -10.552 28.947  1    83.97  ? 322 GLN D O   1 
ATOM   1239 C  CB  . GLN A 1 152 ? -66.468 -12.876 30.296  1    70.53  ? 322 GLN D CB  1 
ATOM   1240 C  CG  . GLN A 1 152 ? -65.422 -13.972 30.377  1    70.58  ? 322 GLN D CG  1 
ATOM   1241 C  CD  . GLN A 1 152 ? -65.165 -14.317 31.82   1    73.72  ? 322 GLN D CD  1 
ATOM   1242 O  OE1 . GLN A 1 152 ? -65.796 -15.23  32.364  1    78.33  ? 322 GLN D OE1 1 
ATOM   1243 N  NE2 . GLN A 1 152 ? -64.321 -13.519 32.464  1    68.56  ? 322 GLN D NE2 1 
ATOM   1244 N  N   . GLN A 1 153 ? -69.34  -12.44  29.267  1    85.61  ? 323 GLN D N   1 
ATOM   1245 C  CA  . GLN A 1 153 ? -70.647 -11.811 29.409  1    92.07  ? 323 GLN D CA  1 
ATOM   1246 C  C   . GLN A 1 153 ? -71.6   -12.824 30.047  1    91.07  ? 323 GLN D C   1 
ATOM   1247 O  O   . GLN A 1 153 ? -72.19  -13.664 29.359  1    87.96  ? 323 GLN D O   1 
ATOM   1248 C  CB  . GLN A 1 153 ? -71.152 -11.166 28.111  1    102    ? 323 GLN D CB  1 
ATOM   1249 C  CG  . GLN A 1 153 ? -70.92  -11.995 26.848  1    104.32 ? 323 GLN D CG  1 
ATOM   1250 C  CD  . GLN A 1 153 ? -71.513 -11.395 25.586  1    108.92 ? 323 GLN D CD  1 
ATOM   1251 O  OE1 . GLN A 1 153 ? -71.387 -11.96  24.496  1    104.95 ? 323 GLN D OE1 1 
ATOM   1252 N  NE2 . GLN A 1 153 ? -72.175 -10.25  25.712  1    112.33 ? 323 GLN D NE2 1 
ATOM   1253 N  N   . PRO A 1 154 ? -71.73  -12.819 31.397  1    90.26  ? 324 PRO D N   1 
ATOM   1254 C  CA  . PRO A 1 154 ? -71.038 -11.849 32.25   1    85.08  ? 324 PRO D CA  1 
ATOM   1255 C  C   . PRO A 1 154 ? -69.671 -12.428 32.6    1    86.17  ? 324 PRO D C   1 
ATOM   1256 O  O   . PRO A 1 154 ? -69.345 -13.537 32.174  1    81.72  ? 324 PRO D O   1 
ATOM   1257 C  CB  . PRO A 1 154 ? -71.953 -11.874 33.47   1    87.34  ? 324 PRO D CB  1 
ATOM   1258 C  CG  . PRO A 1 154 ? -72.343 -13.341 33.609  1    90.7   ? 324 PRO D CG  1 
ATOM   1259 C  CD  . PRO A 1 154 ? -72.504 -13.812 32.171  1    92.39  ? 324 PRO D CD  1 
ATOM   1260 N  N   . ALA A 1 155 ? -68.908 -11.68  33.413  1    87.41  ? 325 ALA D N   1 
ATOM   1261 C  CA  . ALA A 1 155 ? -67.698 -12.172 34.058  1    82.53  ? 325 ALA D CA  1 
ATOM   1262 C  C   . ALA A 1 155 ? -68.048 -13.327 34.997  1    87.27  ? 325 ALA D C   1 
ATOM   1263 O  O   . ALA A 1 155 ? -69.056 -13.254 35.698  1    90.9   ? 325 ALA D O   1 
ATOM   1264 C  CB  . ALA A 1 155 ? -67.047 -11.046 34.82   1    76.71  ? 325 ALA D CB  1 
ATOM   1265 N  N   . ASN A 1 156 ? -67.228 -14.397 34.957  1    87.17  ? 326 ASN D N   1 
ATOM   1266 C  CA  . ASN A 1 156 ? -67.253 -15.519 35.89   1    83.68  ? 326 ASN D CA  1 
ATOM   1267 C  C   . ASN A 1 156 ? -65.869 -15.62  36.523  1    84.31  ? 326 ASN D C   1 
ATOM   1268 O  O   . ASN A 1 156 ? -64.873 -15.807 35.824  1    84.08  ? 326 ASN D O   1 
ATOM   1269 C  CB  . ASN A 1 156 ? -67.569 -16.85  35.207  1    86.32  ? 326 ASN D CB  1 
ATOM   1270 C  CG  . ASN A 1 156 ? -68.009 -17.943 36.159  1    90.78  ? 326 ASN D CG  1 
ATOM   1271 O  OD1 . ASN A 1 156 ? -67.31  -18.28  37.13   1    91.49  ? 326 ASN D OD1 1 
ATOM   1272 N  ND2 . ASN A 1 156 ? -69.17  -18.52  35.883  1    88.17  ? 326 ASN D ND2 1 
ATOM   1273 N  N   . CYS A 1 157 ? -65.824 -15.48  37.853  1    85.19  ? 327 CYS D N   1 
ATOM   1274 C  CA  . CYS A 1 157 ? -64.584 -15.423 38.613  1    83.75  ? 327 CYS D CA  1 
ATOM   1275 C  C   . CYS A 1 157 ? -63.892 -16.786 38.611  1    79.27  ? 327 CYS D C   1 
ATOM   1276 O  O   . CYS A 1 157 ? -62.668 -16.849 38.72   1    76.43  ? 327 CYS D O   1 
ATOM   1277 C  CB  . CYS A 1 157 ? -64.85  -14.958 40.039  1    90.21  ? 327 CYS D CB  1 
ATOM   1278 S  SG  . CYS A 1 157 ? -66.263 -15.829 40.764  1    121.38 ? 327 CYS D SG  1 
ATOM   1279 N  N   . LYS A 1 158 ? -64.678 -17.864 38.494  1    80.49  ? 328 LYS D N   1 
ATOM   1280 C  CA  . LYS A 1 158 ? -64.143 -19.216 38.47   1    80.68  ? 328 LYS D CA  1 
ATOM   1281 C  C   . LYS A 1 158 ? -63.496 -19.524 37.121  1    78.29  ? 328 LYS D C   1 
ATOM   1282 O  O   . LYS A 1 158 ? -62.47  -20.204 37.063  1    78.7   ? 328 LYS D O   1 
ATOM   1283 C  CB  . LYS A 1 158 ? -65.203 -20.233 38.892  1    83.49  ? 328 LYS D CB  1 
ATOM   1284 C  CG  . LYS A 1 158 ? -65.408 -20.259 40.402  1    88.61  ? 328 LYS D CG  1 
ATOM   1285 C  CD  . LYS A 1 158 ? -66.046 -21.543 40.926  1    94.44  ? 328 LYS D CD  1 
ATOM   1286 C  CE  . LYS A 1 158 ? -67.331 -21.954 40.277  1    94.57  ? 328 LYS D CE  1 
ATOM   1287 N  NZ  . LYS A 1 158 ? -67.697 -23.308 40.705  1    99.13  ? 328 LYS D NZ  1 
ATOM   1288 N  N   . VAL A 1 159 ? -64.095 -19.018 36.039  1    75.19  ? 329 VAL D N   1 
ATOM   1289 C  CA  . VAL A 1 159 ? -63.425 -19.045 34.75   1    69.7   ? 329 VAL D CA  1 
ATOM   1290 C  C   . VAL A 1 159 ? -62.078 -18.324 34.879  1    67.3   ? 329 VAL D C   1 
ATOM   1291 O  O   . VAL A 1 159 ? -61.065 -18.852 34.44   1    66     ? 329 VAL D O   1 
ATOM   1292 C  CB  . VAL A 1 159 ? -64.299 -18.473 33.615  1    67.22  ? 329 VAL D CB  1 
ATOM   1293 C  CG1 . VAL A 1 159 ? -63.559 -18.417 32.29   1    64.12  ? 329 VAL D CG1 1 
ATOM   1294 C  CG2 . VAL A 1 159 ? -65.585 -19.259 33.437  1    70.7   ? 329 VAL D CG2 1 
ATOM   1295 N  N   . GLU A 1 160 ? -62.057 -17.134 35.502  1    66.57  ? 330 GLU D N   1 
ATOM   1296 C  CA  . GLU A 1 160 ? -60.867 -16.285 35.511  1    63.69  ? 330 GLU D CA  1 
ATOM   1297 C  C   . GLU A 1 160 ? -59.745 -16.939 36.312  1    60.51  ? 330 GLU D C   1 
ATOM   1298 O  O   . GLU A 1 160 ? -58.636 -17.081 35.8    1    57.66  ? 330 GLU D O   1 
ATOM   1299 C  CB  . GLU A 1 160 ? -61.136 -14.865 36.007  1    64.79  ? 330 GLU D CB  1 
ATOM   1300 C  CG  . GLU A 1 160 ? -61.96  -14.057 35.011  1    70.49  ? 330 GLU D CG  1 
ATOM   1301 C  CD  . GLU A 1 160 ? -62.368 -12.652 35.404  1    70.13  ? 330 GLU D CD  1 
ATOM   1302 O  OE1 . GLU A 1 160 ? -61.885 -12.19  36.455  1    69.89  ? 330 GLU D OE1 1 
ATOM   1303 O  OE2 . GLU A 1 160 ? -63.156 -12.038 34.644  1    68.7   ? 330 GLU D OE2 1 
ATOM   1304 N  N   . SER A 1 161 ? -60.053 -17.327 37.556  1    59.4   ? 331 SER D N   1 
ATOM   1305 C  CA  . SER A 1 161 ? -59.165 -18.115 38.397  1    59.42  ? 331 SER D CA  1 
ATOM   1306 C  C   . SER A 1 161 ? -58.595 -19.33  37.665  1    59.04  ? 331 SER D C   1 
ATOM   1307 O  O   . SER A 1 161 ? -57.391 -19.531 37.708  1    59.94  ? 331 SER D O   1 
ATOM   1308 C  CB  . SER A 1 161 ? -59.831 -18.529 39.679  1    61.33  ? 331 SER D CB  1 
ATOM   1309 O  OG  . SER A 1 161 ? -59.786 -17.469 40.622  1    63.38  ? 331 SER D OG  1 
ATOM   1310 N  N   . LEU A 1 162 ? -59.454 -20.15  37.043  1    62.04  ? 332 LEU D N   1 
ATOM   1311 C  CA  . LEU A 1 162 ? -59.036 -21.401 36.419  1    62.05  ? 332 LEU D CA  1 
ATOM   1312 C  C   . LEU A 1 162 ? -58.052 -21.149 35.275  1    59.58  ? 332 LEU D C   1 
ATOM   1313 O  O   . LEU A 1 162 ? -57.078 -21.886 35.132  1    61.51  ? 332 LEU D O   1 
ATOM   1314 C  CB  . LEU A 1 162 ? -60.259 -22.195 35.952  1    65.15  ? 332 LEU D CB  1 
ATOM   1315 C  CG  . LEU A 1 162 ? -60.001 -23.538 35.251  1    67.42  ? 332 LEU D CG  1 
ATOM   1316 C  CD1 . LEU A 1 162 ? -59.14  -24.467 36.066  1    67.76  ? 332 LEU D CD1 1 
ATOM   1317 C  CD2 . LEU A 1 162 ? -61.275 -24.276 34.908  1    74.12  ? 332 LEU D CD2 1 
ATOM   1318 N  N   . ALA A 1 163 ? -58.307 -20.117 34.459  1    55.95  ? 333 ALA D N   1 
ATOM   1319 C  CA  . ALA A 1 163 ? -57.412 -19.762 33.37   1    56.53  ? 333 ALA D CA  1 
ATOM   1320 C  C   . ALA A 1 163 ? -56.079 -19.227 33.896  1    56.9   ? 333 ALA D C   1 
ATOM   1321 O  O   . ALA A 1 163 ? -55.036 -19.474 33.279  1    60.21  ? 333 ALA D O   1 
ATOM   1322 C  CB  . ALA A 1 163 ? -58.078 -18.823 32.386  1    54.28  ? 333 ALA D CB  1 
ATOM   1323 N  N   . MET A 1 164 ? -56.109 -18.512 35.033  1    56.39  ? 334 MET D N   1 
ATOM   1324 C  CA  . MET A 1 164 ? -54.88  -18.094 35.702  1    57.39  ? 334 MET D CA  1 
ATOM   1325 C  C   . MET A 1 164 ? -54.075 -19.334 36.118  1    60.01  ? 334 MET D C   1 
ATOM   1326 O  O   . MET A 1 164 ? -52.855 -19.383 35.888  1    57.51  ? 334 MET D O   1 
ATOM   1327 C  CB  . MET A 1 164 ? -55.154 -17.177 36.907  1    56.33  ? 334 MET D CB  1 
ATOM   1328 C  CG  . MET A 1 164 ? -55.534 -15.725 36.59   1    59.58  ? 334 MET D CG  1 
ATOM   1329 S  SD  . MET A 1 164 ? -54.3   -14.825 35.621  1    69.14  ? 334 MET D SD  1 
ATOM   1330 C  CE  . MET A 1 164 ? -54.139 -13.294 36.559  1    77.22  ? 334 MET D CE  1 
ATOM   1331 N  N   . PHE A 1 165 ? -54.786 -20.34  36.675  1    55.5   ? 335 PHE D N   1 
ATOM   1332 C  CA  . PHE A 1 165 ? -54.185 -21.538 37.251  1    55.22  ? 335 PHE D CA  1 
ATOM   1333 C  C   . PHE A 1 165 ? -53.45  -22.337 36.184  1    53.82  ? 335 PHE D C   1 
ATOM   1334 O  O   . PHE A 1 165 ? -52.325 -22.762 36.413  1    50.32  ? 335 PHE D O   1 
ATOM   1335 C  CB  . PHE A 1 165 ? -55.249 -22.449 37.869  1    57.26  ? 335 PHE D CB  1 
ATOM   1336 C  CG  . PHE A 1 165 ? -54.833 -23.875 38.184  1    55.98  ? 335 PHE D CG  1 
ATOM   1337 C  CD1 . PHE A 1 165 ? -53.757 -24.157 39.013  1    56.07  ? 335 PHE D CD1 1 
ATOM   1338 C  CD2 . PHE A 1 165 ? -55.545 -24.943 37.657  1    57.93  ? 335 PHE D CD2 1 
ATOM   1339 C  CE1 . PHE A 1 165 ? -53.417 -25.474 39.307  1    58.29  ? 335 PHE D CE1 1 
ATOM   1340 C  CE2 . PHE A 1 165 ? -55.207 -26.257 37.958  1    58.17  ? 335 PHE D CE2 1 
ATOM   1341 C  CZ  . PHE A 1 165 ? -54.143 -26.527 38.779  1    58.21  ? 335 PHE D CZ  1 
ATOM   1342 N  N   . LEU A 1 166 ? -54.126 -22.564 35.049  1    56.35  ? 336 LEU D N   1 
ATOM   1343 C  CA  . LEU A 1 166 ? -53.576 -23.35  33.96   1    55.09  ? 336 LEU D CA  1 
ATOM   1344 C  C   . LEU A 1 166 ? -52.385 -22.594 33.383  1    56.69  ? 336 LEU D C   1 
ATOM   1345 O  O   . LEU A 1 166 ? -51.363 -23.21  33.054  1    56.93  ? 336 LEU D O   1 
ATOM   1346 C  CB  . LEU A 1 166 ? -54.64  -23.621 32.902  1    53.78  ? 336 LEU D CB  1 
ATOM   1347 C  CG  . LEU A 1 166 ? -55.865 -24.424 33.353  1    57.95  ? 336 LEU D CG  1 
ATOM   1348 C  CD1 . LEU A 1 166 ? -57.023 -24.235 32.385  1    58.1   ? 336 LEU D CD1 1 
ATOM   1349 C  CD2 . LEU A 1 166 ? -55.562 -25.907 33.467  1    57.59  ? 336 LEU D CD2 1 
ATOM   1350 N  N   . GLY A 1 167 ? -52.535 -21.262 33.274  1    51.67  ? 337 GLY D N   1 
ATOM   1351 C  CA  . GLY A 1 167 ? -51.463 -20.403 32.785  1    49.24  ? 337 GLY D CA  1 
ATOM   1352 C  C   . GLY A 1 167 ? -50.148 -20.599 33.547  1    48     ? 337 GLY D C   1 
ATOM   1353 O  O   . GLY A 1 167 ? -49.091 -20.723 32.937  1    47.5   ? 337 GLY D O   1 
ATOM   1354 N  N   . GLU A 1 168 ? -50.222 -20.639 34.885  1    48.8   ? 338 GLU D N   1 
ATOM   1355 C  CA  . GLU A 1 168 ? -49.04  -20.777 35.718  1    48.42  ? 338 GLU D CA  1 
ATOM   1356 C  C   . GLU A 1 168 ? -48.429 -22.172 35.571  1    52.14  ? 338 GLU D C   1 
ATOM   1357 O  O   . GLU A 1 168 ? -47.206 -22.291 35.634  1    58.04  ? 338 GLU D O   1 
ATOM   1358 C  CB  . GLU A 1 168 ? -49.31  -20.523 37.202  1    46.43  ? 338 GLU D CB  1 
ATOM   1359 C  CG  . GLU A 1 168 ? -49.914 -19.161 37.491  1    48.6   ? 338 GLU D CG  1 
ATOM   1360 C  CD  . GLU A 1 168 ? -49.745 -18.674 38.917  1    56.09  ? 338 GLU D CD  1 
ATOM   1361 O  OE1 . GLU A 1 168 ? -49.121 -19.372 39.763  1    55.28  ? 338 GLU D OE1 1 
ATOM   1362 O  OE2 . GLU A 1 168 ? -50.244 -17.542 39.148  1    56.87  ? 338 GLU D OE2 1 
ATOM   1363 N  N   . LEU A 1 169 ? -49.266 -23.217 35.426  1    49.27  ? 339 LEU D N   1 
ATOM   1364 C  CA  . LEU A 1 169 ? -48.775 -24.586 35.318  1    49.65  ? 339 LEU D CA  1 
ATOM   1365 C  C   . LEU A 1 169 ? -47.797 -24.69  34.159  1    50.34  ? 339 LEU D C   1 
ATOM   1366 O  O   . LEU A 1 169 ? -46.858 -25.466 34.233  1    58.33  ? 339 LEU D O   1 
ATOM   1367 C  CB  . LEU A 1 169 ? -49.893 -25.618 35.151  1    50.95  ? 339 LEU D CB  1 
ATOM   1368 C  CG  . LEU A 1 169 ? -50.752 -25.934 36.383  1    50.7   ? 339 LEU D CG  1 
ATOM   1369 C  CD1 . LEU A 1 169 ? -51.727 -27.022 36.025  1    53.71  ? 339 LEU D CD1 1 
ATOM   1370 C  CD2 . LEU A 1 169 ? -49.958 -26.362 37.612  1    47.71  ? 339 LEU D CD2 1 
ATOM   1371 N  N   . SER A 1 170 ? -48.039 -23.898 33.108  1    49.8   ? 340 SER D N   1 
ATOM   1372 C  CA  . SER A 1 170 ? -47.225 -23.891 31.909  1    50.05  ? 340 SER D CA  1 
ATOM   1373 C  C   . SER A 1 170 ? -45.835 -23.326 32.206  1    51.48  ? 340 SER D C   1 
ATOM   1374 O  O   . SER A 1 170 ? -44.865 -23.715 31.553  1    54.91  ? 340 SER D O   1 
ATOM   1375 C  CB  . SER A 1 170 ? -47.921 -23.173 30.761  1    48.54  ? 340 SER D CB  1 
ATOM   1376 O  OG  . SER A 1 170 ? -47.883 -21.757 30.906  1    49.92  ? 340 SER D OG  1 
ATOM   1377 N  N   . LEU A 1 171 ? -45.741 -22.374 33.15   1    50.05  ? 341 LEU D N   1 
ATOM   1378 C  CA  . LEU A 1 171 ? -44.462 -21.783 33.53   1    44.9   ? 341 LEU D CA  1 
ATOM   1379 C  C   . LEU A 1 171 ? -43.463 -22.892 33.901  1    44.8   ? 341 LEU D C   1 
ATOM   1380 O  O   . LEU A 1 171 ? -42.262 -22.769 33.678  1    44.63  ? 341 LEU D O   1 
ATOM   1381 C  CB  . LEU A 1 171 ? -44.642 -20.788 34.678  1    40.85  ? 341 LEU D CB  1 
ATOM   1382 C  CG  . LEU A 1 171 ? -45.511 -19.547 34.443  1    37.72  ? 341 LEU D CG  1 
ATOM   1383 C  CD1 . LEU A 1 171 ? -45.492 -18.646 35.682  1    38.13  ? 341 LEU D CD1 1 
ATOM   1384 C  CD2 . LEU A 1 171 ? -45.082 -18.746 33.232  1    34.8   ? 341 LEU D CD2 1 
ATOM   1385 N  N   . ILE A 1 172 ? -43.969 -23.986 34.475  1    43.95  ? 342 ILE D N   1 
ATOM   1386 C  CA  . ILE A 1 172 ? -43.122 -24.976 35.119  1    46.24  ? 342 ILE D CA  1 
ATOM   1387 C  C   . ILE A 1 172 ? -42.34  -25.806 34.091  1    48.37  ? 342 ILE D C   1 
ATOM   1388 O  O   . ILE A 1 172 ? -41.169 -26.144 34.308  1    48.55  ? 342 ILE D O   1 
ATOM   1389 C  CB  . ILE A 1 172 ? -43.98  -25.866 36.04   1    44.7   ? 342 ILE D CB  1 
ATOM   1390 C  CG1 . ILE A 1 172 ? -44.682 -25.058 37.128  1    42.92  ? 342 ILE D CG1 1 
ATOM   1391 C  CG2 . ILE A 1 172 ? -43.146 -26.999 36.636  1    47.18  ? 342 ILE D CG2 1 
ATOM   1392 C  CD1 . ILE A 1 172 ? -43.793 -24.678 38.299  1    41.72  ? 342 ILE D CD1 1 
ATOM   1393 N  N   . ASP A 1 173 ? -43.018 -26.196 33.009  1    46.59  ? 343 ASP D N   1 
ATOM   1394 C  CA  . ASP A 1 173 ? -42.502 -27.209 32.102  1    48.24  ? 343 ASP D CA  1 
ATOM   1395 C  C   . ASP A 1 173 ? -42.059 -26.563 30.793  1    49.13  ? 343 ASP D C   1 
ATOM   1396 O  O   . ASP A 1 173 ? -42.89  -26.285 29.927  1    50.1   ? 343 ASP D O   1 
ATOM   1397 C  CB  . ASP A 1 173 ? -43.592 -28.221 31.819  1    51.41  ? 343 ASP D CB  1 
ATOM   1398 C  CG  . ASP A 1 173 ? -44.125 -28.876 33.072  1    55.85  ? 343 ASP D CG  1 
ATOM   1399 O  OD1 . ASP A 1 173 ? -43.266 -29.45  33.789  1    55.31  ? 343 ASP D OD1 1 
ATOM   1400 O  OD2 . ASP A 1 173 ? -45.369 -28.781 33.304  1    59.75  ? 343 ASP D OD2 1 
ATOM   1401 N  N   . ALA A 1 174 ? -40.752 -26.34  30.639  1    47.64  ? 344 ALA D N   1 
ATOM   1402 C  CA  . ALA A 1 174 ? -40.244 -25.738 29.417  1    50.14  ? 344 ALA D CA  1 
ATOM   1403 C  C   . ALA A 1 174 ? -40.588 -26.629 28.221  1    56.21  ? 344 ALA D C   1 
ATOM   1404 O  O   . ALA A 1 174 ? -40.747 -26.141 27.101  1    55.76  ? 344 ALA D O   1 
ATOM   1405 C  CB  . ALA A 1 174 ? -38.751 -25.527 29.521  1    50.47  ? 344 ALA D CB  1 
ATOM   1406 N  N   . ASP A 1 175 ? -40.642 -27.945 28.461  1    55.78  ? 345 ASP D N   1 
ATOM   1407 C  CA  . ASP A 1 175 ? -41.197 -28.852 27.473  1    57.94  ? 345 ASP D CA  1 
ATOM   1408 C  C   . ASP A 1 175 ? -42.615 -29.234 27.892  1    58.89  ? 345 ASP D C   1 
ATOM   1409 O  O   . ASP A 1 175 ? -42.802 -29.901 28.905  1    56.24  ? 345 ASP D O   1 
ATOM   1410 C  CB  . ASP A 1 175 ? -40.318 -30.071 27.278  1    58.24  ? 345 ASP D CB  1 
ATOM   1411 C  CG  . ASP A 1 175 ? -40.807 -31.073 26.249  1    61.65  ? 345 ASP D CG  1 
ATOM   1412 O  OD1 . ASP A 1 175 ? -41.989 -31.019 25.834  1    65.38  ? 345 ASP D OD1 1 
ATOM   1413 O  OD2 . ASP A 1 175 ? -39.983 -31.886 25.852  1    63.45  ? 345 ASP D OD2 1 
ATOM   1414 N  N   . PRO A 1 176 ? -43.659 -28.878 27.104  1    61.44  ? 346 PRO D N   1 
ATOM   1415 C  CA  . PRO A 1 176 ? -43.474 -28.223 25.8    1    57.47  ? 346 PRO D CA  1 
ATOM   1416 C  C   . PRO A 1 176 ? -43.633 -26.703 25.668  1    55.52  ? 346 PRO D C   1 
ATOM   1417 O  O   . PRO A 1 176 ? -43.547 -26.198 24.559  1    56.64  ? 346 PRO D O   1 
ATOM   1418 C  CB  . PRO A 1 176 ? -44.596 -28.955 25.025  1    57.1   ? 346 PRO D CB  1 
ATOM   1419 C  CG  . PRO A 1 176 ? -45.726 -29.06  26.04   1    57.88  ? 346 PRO D CG  1 
ATOM   1420 C  CD  . PRO A 1 176 ? -45.074 -29.167 27.411  1    56.68  ? 346 PRO D CD  1 
ATOM   1421 N  N   . TYR A 1 177 ? -43.845 -25.972 26.771  1    49.05  ? 347 TYR D N   1 
ATOM   1422 C  CA  . TYR A 1 177 ? -44.482 -24.662 26.698  1    49.09  ? 347 TYR D CA  1 
ATOM   1423 C  C   . TYR A 1 177 ? -43.591 -23.568 26.1    1    50.6   ? 347 TYR D C   1 
ATOM   1424 O  O   . TYR A 1 177 ? -44.115 -22.528 25.688  1    54.05  ? 347 TYR D O   1 
ATOM   1425 C  CB  . TYR A 1 177 ? -45.198 -24.282 28.003  1    48.54  ? 347 TYR D CB  1 
ATOM   1426 C  CG  . TYR A 1 177 ? -46.353 -25.234 28.28   1    56.04  ? 347 TYR D CG  1 
ATOM   1427 C  CD1 . TYR A 1 177 ? -47.48  -25.259 27.455  1    58.86  ? 347 TYR D CD1 1 
ATOM   1428 C  CD2 . TYR A 1 177 ? -46.29  -26.167 29.309  1    58.87  ? 347 TYR D CD2 1 
ATOM   1429 C  CE1 . TYR A 1 177 ? -48.512 -26.166 27.66   1    60.97  ? 347 TYR D CE1 1 
ATOM   1430 C  CE2 . TYR A 1 177 ? -47.322 -27.068 29.528  1    62.52  ? 347 TYR D CE2 1 
ATOM   1431 C  CZ  . TYR A 1 177 ? -48.438 -27.075 28.705  1    61.04  ? 347 TYR D CZ  1 
ATOM   1432 O  OH  . TYR A 1 177 ? -49.45  -27.968 28.941  1    54.44  ? 347 TYR D OH  1 
ATOM   1433 N  N   . LEU A 1 178 ? -42.27  -23.787 26.012  1    48.46  ? 348 LEU D N   1 
ATOM   1434 C  CA  . LEU A 1 178 ? -41.41  -22.813 25.345  1    48.75  ? 348 LEU D CA  1 
ATOM   1435 C  C   . LEU A 1 178 ? -41.719 -22.678 23.844  1    54.94  ? 348 LEU D C   1 
ATOM   1436 O  O   . LEU A 1 178 ? -41.313 -21.695 23.216  1    58.43  ? 348 LEU D O   1 
ATOM   1437 C  CB  . LEU A 1 178 ? -39.924 -23.105 25.546  1    47.72  ? 348 LEU D CB  1 
ATOM   1438 C  CG  . LEU A 1 178 ? -39.268 -22.598 26.829  1    47.57  ? 348 LEU D CG  1 
ATOM   1439 C  CD1 . LEU A 1 178 ? -37.837 -23.051 26.82   1    48.7   ? 348 LEU D CD1 1 
ATOM   1440 C  CD2 . LEU A 1 178 ? -39.299 -21.106 26.943  1    46.81  ? 348 LEU D CD2 1 
ATOM   1441 N  N   . LYS A 1 179 ? -42.414 -23.654 23.243  1    57.8   ? 349 LYS D N   1 
ATOM   1442 C  CA  . LYS A 1 179 ? -42.702 -23.542 21.822  1    58.58  ? 349 LYS D CA  1 
ATOM   1443 C  C   . LYS A 1 179 ? -43.941 -22.673 21.577  1    64.67  ? 349 LYS D C   1 
ATOM   1444 O  O   . LYS A 1 179 ? -44.186 -22.293 20.432  1    67.73  ? 349 LYS D O   1 
ATOM   1445 C  CB  . LYS A 1 179 ? -42.704 -24.874 21.077  1    55.35  ? 349 LYS D CB  1 
ATOM   1446 C  CG  . LYS A 1 179 ? -43.849 -25.805 21.354  1    59.3   ? 349 LYS D CG  1 
ATOM   1447 C  CD  . LYS A 1 179 ? -43.474 -27.263 21.076  1    65.32  ? 349 LYS D CD  1 
ATOM   1448 C  CE  . LYS A 1 179 ? -44.682 -28.153 20.95   1    71.74  ? 349 LYS D CE  1 
ATOM   1449 N  NZ  . LYS A 1 179 ? -44.384 -29.486 20.417  1    76.3   ? 349 LYS D NZ  1 
ATOM   1450 N  N   . TYR A 1 180 ? -44.676 -22.308 22.645  1    58.69  ? 350 TYR D N   1 
ATOM   1451 C  CA  . TYR A 1 180 ? -45.9   -21.53  22.489  1    55.55  ? 350 TYR D CA  1 
ATOM   1452 C  C   . TYR A 1 180 ? -45.706 -20.114 23.011  1    55.07  ? 350 TYR D C   1 
ATOM   1453 O  O   . TYR A 1 180 ? -45.126 -19.925 24.076  1    59.3   ? 350 TYR D O   1 
ATOM   1454 C  CB  . TYR A 1 180 ? -47.075 -22.163 23.234  1    53.66  ? 350 TYR D CB  1 
ATOM   1455 C  CG  . TYR A 1 180 ? -47.366 -23.593 22.792  1    54.72  ? 350 TYR D CG  1 
ATOM   1456 C  CD1 . TYR A 1 180 ? -47.886 -23.86  21.526  1    54.22  ? 350 TYR D CD1 1 
ATOM   1457 C  CD2 . TYR A 1 180 ? -47.125 -24.666 23.647  1    50.55  ? 350 TYR D CD2 1 
ATOM   1458 C  CE1 . TYR A 1 180 ? -48.171 -25.155 21.13   1    57.79  ? 350 TYR D CE1 1 
ATOM   1459 C  CE2 . TYR A 1 180 ? -47.408 -25.961 23.255  1    51.68  ? 350 TYR D CE2 1 
ATOM   1460 C  CZ  . TYR A 1 180 ? -47.934 -26.204 22.001  1    54.59  ? 350 TYR D CZ  1 
ATOM   1461 O  OH  . TYR A 1 180 ? -48.186 -27.476 21.623  1    53.87  ? 350 TYR D OH  1 
ATOM   1462 N  N   . LEU A 1 181 ? -46.209 -19.143 22.248  1    51.54  ? 351 LEU D N   1 
ATOM   1463 C  CA  . LEU A 1 181 ? -46.201 -17.739 22.623  1    49.4   ? 351 LEU D CA  1 
ATOM   1464 C  C   . LEU A 1 181 ? -47.175 -17.502 23.775  1    50.14  ? 351 LEU D C   1 
ATOM   1465 O  O   . LEU A 1 181 ? -48.154 -18.23  23.936  1    52.21  ? 351 LEU D O   1 
ATOM   1466 C  CB  . LEU A 1 181 ? -46.58  -16.87  21.428  1    45.45  ? 351 LEU D CB  1 
ATOM   1467 C  CG  . LEU A 1 181 ? -45.47  -16.626 20.411  1    44.67  ? 351 LEU D CG  1 
ATOM   1468 C  CD1 . LEU A 1 181 ? -46.004 -15.922 19.175  1    44.06  ? 351 LEU D CD1 1 
ATOM   1469 C  CD2 . LEU A 1 181 ? -44.451 -15.758 21.112  1    46.65  ? 351 LEU D CD2 1 
ATOM   1470 N  N   . PRO A 1 182 ? -46.94  -16.473 24.619  1    47.39  ? 352 PRO D N   1 
ATOM   1471 C  CA  . PRO A 1 182 ? -47.822 -16.215 25.759  1    46.2   ? 352 PRO D CA  1 
ATOM   1472 C  C   . PRO A 1 182 ? -49.279 -16.067 25.343  1    49.77  ? 352 PRO D C   1 
ATOM   1473 O  O   . PRO A 1 182 ? -50.174 -16.585 26.013  1    54.89  ? 352 PRO D O   1 
ATOM   1474 C  CB  . PRO A 1 182 ? -47.24  -14.927 26.336  1    45.04  ? 352 PRO D CB  1 
ATOM   1475 C  CG  . PRO A 1 182 ? -45.767 -15.03  25.989  1    43.42  ? 352 PRO D CG  1 
ATOM   1476 C  CD  . PRO A 1 182 ? -45.767 -15.581 24.571  1    43.53  ? 352 PRO D CD  1 
ATOM   1477 N  N   . SER A 1 183 ? -49.496 -15.391 24.21   1    48.5   ? 353 SER D N   1 
ATOM   1478 C  CA  . SER A 1 183 ? -50.842 -15.102 23.748  1    47.01  ? 353 SER D CA  1 
ATOM   1479 C  C   . SER A 1 183 ? -51.553 -16.378 23.306  1    49.84  ? 353 SER D C   1 
ATOM   1480 O  O   . SER A 1 183 ? -52.784 -16.408 23.285  1    54.05  ? 353 SER D O   1 
ATOM   1481 C  CB  . SER A 1 183 ? -50.843 -14.063 22.67   1    47.25  ? 353 SER D CB  1 
ATOM   1482 O  OG  . SER A 1 183 ? -50.273 -14.579 21.481  1    50.71  ? 353 SER D OG  1 
ATOM   1483 N  N   . VAL A 1 184 ? -50.778 -17.42  22.976  1    48.85  ? 354 VAL D N   1 
ATOM   1484 C  CA  . VAL A 1 184 ? -51.33  -18.711 22.596  1    48.9   ? 354 VAL D CA  1 
ATOM   1485 C  C   . VAL A 1 184 ? -51.687 -19.497 23.855  1    48.45  ? 354 VAL D C   1 
ATOM   1486 O  O   . VAL A 1 184 ? -52.786 -20.044 23.988  1    51.51  ? 354 VAL D O   1 
ATOM   1487 C  CB  . VAL A 1 184 ? -50.398 -19.519 21.672  1    49.65  ? 354 VAL D CB  1 
ATOM   1488 C  CG1 . VAL A 1 184 ? -50.946 -20.915 21.403  1    49.55  ? 354 VAL D CG1 1 
ATOM   1489 C  CG2 . VAL A 1 184 ? -50.137 -18.81  20.35   1    52.29  ? 354 VAL D CG2 1 
ATOM   1490 N  N   . ILE A 1 185 ? -50.728 -19.576 24.772  1    46.37  ? 355 ILE D N   1 
ATOM   1491 C  CA  . ILE A 1 185 ? -50.956 -20.302 26.004  1    47.5   ? 355 ILE D CA  1 
ATOM   1492 C  C   . ILE A 1 185 ? -52.156 -19.675 26.704  1    49.71  ? 355 ILE D C   1 
ATOM   1493 O  O   . ILE A 1 185 ? -52.991 -20.4   27.215  1    50.5   ? 355 ILE D O   1 
ATOM   1494 C  CB  . ILE A 1 185 ? -49.698 -20.286 26.88   1    43.75  ? 355 ILE D CB  1 
ATOM   1495 C  CG1 . ILE A 1 185 ? -48.593 -21.161 26.268  1    45.09  ? 355 ILE D CG1 1 
ATOM   1496 C  CG2 . ILE A 1 185 ? -50.063 -20.724 28.292  1    43.66  ? 355 ILE D CG2 1 
ATOM   1497 C  CD1 . ILE A 1 185 ? -47.212 -20.906 26.847  1    41.21  ? 355 ILE D CD1 1 
ATOM   1498 N  N   . ALA A 1 186 ? -52.235 -18.336 26.69   1    47.75  ? 356 ALA D N   1 
ATOM   1499 C  CA  . ALA A 1 186 ? -53.317 -17.578 27.303  1    48.24  ? 356 ALA D CA  1 
ATOM   1500 C  C   . ALA A 1 186 ? -54.662 -18.023 26.752  1    53.58  ? 356 ALA D C   1 
ATOM   1501 O  O   . ALA A 1 186 ? -55.572 -18.351 27.513  1    55.05  ? 356 ALA D O   1 
ATOM   1502 C  CB  . ALA A 1 186 ? -53.133 -16.111 27.022  1    46.63  ? 356 ALA D CB  1 
ATOM   1503 N  N   . ALA A 1 187 ? -54.762 -18.003 25.416  1    54.13  ? 357 ALA D N   1 
ATOM   1504 C  CA  . ALA A 1 187 ? -55.95  -18.37  24.667  1    53.62  ? 357 ALA D CA  1 
ATOM   1505 C  C   . ALA A 1 187 ? -56.382 -19.8   24.983  1    58.09  ? 357 ALA D C   1 
ATOM   1506 O  O   . ALA A 1 187 ? -57.578 -20.046 25.13   1    61.6   ? 357 ALA D O   1 
ATOM   1507 C  CB  . ALA A 1 187 ? -55.684 -18.196 23.196  1    51.66  ? 357 ALA D CB  1 
ATOM   1508 N  N   . ALA A 1 188 ? -55.421 -20.732 25.062  1    57.83  ? 358 ALA D N   1 
ATOM   1509 C  CA  . ALA A 1 188 ? -55.736 -22.13  25.316  1    61.56  ? 358 ALA D CA  1 
ATOM   1510 C  C   . ALA A 1 188 ? -56.214 -22.318 26.753  1    60.74  ? 358 ALA D C   1 
ATOM   1511 O  O   . ALA A 1 188 ? -57.137 -23.094 27.004  1    63.69  ? 358 ALA D O   1 
ATOM   1512 C  CB  . ALA A 1 188 ? -54.548 -23.016 25.008  1    61.02  ? 358 ALA D CB  1 
ATOM   1513 N  N   . ALA A 1 189 ? -55.589 -21.58  27.671  1    54.52  ? 359 ALA D N   1 
ATOM   1514 C  CA  . ALA A 1 189 ? -55.931 -21.629 29.084  1    57.47  ? 359 ALA D CA  1 
ATOM   1515 C  C   . ALA A 1 189 ? -57.324 -21.045 29.335  1    60.84  ? 359 ALA D C   1 
ATOM   1516 O  O   . ALA A 1 189 ? -58.036 -21.471 30.245  1    64.41  ? 359 ALA D O   1 
ATOM   1517 C  CB  . ALA A 1 189 ? -54.877 -20.893 29.876  1    53.03  ? 359 ALA D CB  1 
ATOM   1518 N  N   . PHE A 1 190 ? -57.713 -20.063 28.523  1    57.84  ? 360 PHE D N   1 
ATOM   1519 C  CA  . PHE A 1 190 ? -59.021 -19.448 28.658  1    56.8   ? 360 PHE D CA  1 
ATOM   1520 C  C   . PHE A 1 190 ? -60.128 -20.337 28.06   1    58.66  ? 360 PHE D C   1 
ATOM   1521 O  O   . PHE A 1 190 ? -61.155 -20.523 28.706  1    58.22  ? 360 PHE D O   1 
ATOM   1522 C  CB  . PHE A 1 190 ? -58.964 -18.014 28.133  1    53.24  ? 360 PHE D CB  1 
ATOM   1523 C  CG  . PHE A 1 190 ? -60.322 -17.338 28.095  1    56.96  ? 360 PHE D CG  1 
ATOM   1524 C  CD1 . PHE A 1 190 ? -60.929 -16.912 29.27   1    57.99  ? 360 PHE D CD1 1 
ATOM   1525 C  CD2 . PHE A 1 190 ? -60.992 -17.161 26.894  1    58.89  ? 360 PHE D CD2 1 
ATOM   1526 C  CE1 . PHE A 1 190 ? -62.162 -16.292 29.247  1    58.43  ? 360 PHE D CE1 1 
ATOM   1527 C  CE2 . PHE A 1 190 ? -62.217 -16.525 26.868  1    60.39  ? 360 PHE D CE2 1 
ATOM   1528 C  CZ  . PHE A 1 190 ? -62.796 -16.09  28.043  1    62.19  ? 360 PHE D CZ  1 
ATOM   1529 N  N   . HIS A 1 191 ? -59.935 -20.875 26.843  1    58.72  ? 361 HIS D N   1 
ATOM   1530 C  CA  . HIS A 1 191 ? -60.926 -21.76  26.241  1    63.71  ? 361 HIS D CA  1 
ATOM   1531 C  C   . HIS A 1 191 ? -61.203 -22.915 27.201  1    66.93  ? 361 HIS D C   1 
ATOM   1532 O  O   . HIS A 1 191 ? -62.356 -23.322 27.383  1    68.18  ? 361 HIS D O   1 
ATOM   1533 C  CB  . HIS A 1 191 ? -60.51  -22.329 24.867  1    65.48  ? 361 HIS D CB  1 
ATOM   1534 C  CG  . HIS A 1 191 ? -61.359 -23.514 24.428  1    71.44  ? 361 HIS D CG  1 
ATOM   1535 N  ND1 . HIS A 1 191 ? -62.459 -23.443 23.588  1    73.36  ? 361 HIS D ND1 1 
ATOM   1536 C  CD2 . HIS A 1 191 ? -61.263 -24.818 24.774  1    69.28  ? 361 HIS D CD2 1 
ATOM   1537 C  CE1 . HIS A 1 191 ? -62.985 -24.646 23.433  1    74.33  ? 361 HIS D CE1 1 
ATOM   1538 N  NE2 . HIS A 1 191 ? -62.276 -25.494 24.146  1    74.71  ? 361 HIS D NE2 1 
ATOM   1539 N  N   . LEU A 1 192 ? -60.117 -23.427 27.799  1    65.89  ? 362 LEU D N   1 
ATOM   1540 C  CA  . LEU A 1 192 ? -60.142 -24.644 28.588  1    65.51  ? 362 LEU D CA  1 
ATOM   1541 C  C   . LEU A 1 192 ? -60.759 -24.402 29.971  1    68.12  ? 362 LEU D C   1 
ATOM   1542 O  O   . LEU A 1 192 ? -61.464 -25.276 30.491  1    68.65  ? 362 LEU D O   1 
ATOM   1543 C  CB  . LEU A 1 192 ? -58.708 -25.151 28.643  1    60.93  ? 362 LEU D CB  1 
ATOM   1544 C  CG  . LEU A 1 192 ? -58.501 -26.422 29.464  1    63.01  ? 362 LEU D CG  1 
ATOM   1545 C  CD1 . LEU A 1 192 ? -59.413 -27.557 29.001  1    65.56  ? 362 LEU D CD1 1 
ATOM   1546 C  CD2 . LEU A 1 192 ? -57.045 -26.828 29.448  1    60.65  ? 362 LEU D CD2 1 
ATOM   1547 N  N   . ALA A 1 193 ? -60.504 -23.214 30.546  1    65.18  ? 363 ALA D N   1 
ATOM   1548 C  CA  . ALA A 1 193 ? -61.147 -22.775 31.781  1    69.17  ? 363 ALA D CA  1 
ATOM   1549 C  C   . ALA A 1 193 ? -62.651 -22.575 31.583  1    73.58  ? 363 ALA D C   1 
ATOM   1550 O  O   . ALA A 1 193 ? -63.456 -22.931 32.444  1    77.49  ? 363 ALA D O   1 
ATOM   1551 C  CB  . ALA A 1 193 ? -60.521 -21.493 32.269  1    64.51  ? 363 ALA D CB  1 
ATOM   1552 N  N   . LEU A 1 194 ? -62.998 -21.95  30.452  1    71.8   ? 364 LEU D N   1 
ATOM   1553 C  CA  . LEU A 1 194 ? -64.359 -21.697 30.029  1    72.51  ? 364 LEU D CA  1 
ATOM   1554 C  C   . LEU A 1 194 ? -65.073 -23.029 29.776  1    77.56  ? 364 LEU D C   1 
ATOM   1555 O  O   . LEU A 1 194 ? -66.167 -23.25  30.299  1    79.54  ? 364 LEU D O   1 
ATOM   1556 C  CB  . LEU A 1 194 ? -64.214 -20.849 28.768  1    73.83  ? 364 LEU D CB  1 
ATOM   1557 C  CG  . LEU A 1 194 ? -65.403 -19.991 28.327  1    81.84  ? 364 LEU D CG  1 
ATOM   1558 C  CD1 . LEU A 1 194 ? -65.719 -18.869 29.296  1    83.98  ? 364 LEU D CD1 1 
ATOM   1559 C  CD2 . LEU A 1 194 ? -65.081 -19.407 26.957  1    86.38  ? 364 LEU D CD2 1 
ATOM   1560 N  N   . TYR A 1 195 ? -64.452 -23.927 28.999  1    75.49  ? 365 TYR D N   1 
ATOM   1561 C  CA  . TYR A 1 195 ? -65.068 -25.205 28.684  1    79.21  ? 365 TYR D CA  1 
ATOM   1562 C  C   . TYR A 1 195 ? -65.381 -25.943 29.982  1    81.48  ? 365 TYR D C   1 
ATOM   1563 O  O   . TYR A 1 195 ? -66.482 -26.466 30.161  1    84.36  ? 365 TYR D O   1 
ATOM   1564 C  CB  . TYR A 1 195 ? -64.217 -26.064 27.742  1    81.04  ? 365 TYR D CB  1 
ATOM   1565 C  CG  . TYR A 1 195 ? -64.921 -27.289 27.168  1    84.75  ? 365 TYR D CG  1 
ATOM   1566 C  CD1 . TYR A 1 195 ? -66.007 -27.143 26.305  1    88.26  ? 365 TYR D CD1 1 
ATOM   1567 C  CD2 . TYR A 1 195 ? -64.497 -28.584 27.46   1    85.47  ? 365 TYR D CD2 1 
ATOM   1568 C  CE1 . TYR A 1 195 ? -66.662 -28.238 25.758  1    92.44  ? 365 TYR D CE1 1 
ATOM   1569 C  CE2 . TYR A 1 195 ? -65.147 -29.69  26.922  1    92.02  ? 365 TYR D CE2 1 
ATOM   1570 C  CZ  . TYR A 1 195 ? -66.225 -29.517 26.064  1    94.71  ? 365 TYR D CZ  1 
ATOM   1571 O  OH  . TYR A 1 195 ? -66.88  -30.583 25.519  1    96.54  ? 365 TYR D OH  1 
ATOM   1572 N  N   . THR A 1 196 ? -64.408 -25.938 30.902  1    79.29  ? 366 THR D N   1 
ATOM   1573 C  CA  . THR A 1 196 ? -64.495 -26.733 32.119  1    78.03  ? 366 THR D CA  1 
ATOM   1574 C  C   . THR A 1 196 ? -65.655 -26.247 32.984  1    78.95  ? 366 THR D C   1 
ATOM   1575 O  O   . THR A 1 196 ? -66.383 -27.06  33.554  1    81.24  ? 366 THR D O   1 
ATOM   1576 C  CB  . THR A 1 196 ? -63.181 -26.732 32.901  1    74.12  ? 366 THR D CB  1 
ATOM   1577 O  OG1 . THR A 1 196 ? -62.146 -27.221 32.047  1    69.94  ? 366 THR D OG1 1 
ATOM   1578 C  CG2 . THR A 1 196 ? -63.294 -27.543 34.183  1    71.72  ? 366 THR D CG2 1 
ATOM   1579 N  N   . VAL A 1 197 ? -65.823 -24.922 33.057  1    75.96  ? 367 VAL D N   1 
ATOM   1580 C  CA  . VAL A 1 197 ? -66.729 -24.326 34.023  1    78.04  ? 367 VAL D CA  1 
ATOM   1581 C  C   . VAL A 1 197 ? -68.126 -24.109 33.428  1    82.52  ? 367 VAL D C   1 
ATOM   1582 O  O   . VAL A 1 197 ? -69.12  -24.402 34.093  1    83     ? 367 VAL D O   1 
ATOM   1583 C  CB  . VAL A 1 197 ? -66.116 -23.048 34.624  1    74.31  ? 367 VAL D CB  1 
ATOM   1584 C  CG1 . VAL A 1 197 ? -67.075 -22.345 35.571  1    75.71  ? 367 VAL D CG1 1 
ATOM   1585 C  CG2 . VAL A 1 197 ? -64.824 -23.366 35.357  1    73.03  ? 367 VAL D CG2 1 
ATOM   1586 N  N   . THR A 1 198 ? -68.208 -23.602 32.186  1    83.38  ? 368 THR D N   1 
ATOM   1587 C  CA  . THR A 1 198 ? -69.485 -23.186 31.612  1    84.85  ? 368 THR D CA  1 
ATOM   1588 C  C   . THR A 1 198 ? -69.993 -24.206 30.594  1    86.84  ? 368 THR D C   1 
ATOM   1589 O  O   . THR A 1 198 ? -71.202 -24.39  30.478  1    93.37  ? 368 THR D O   1 
ATOM   1590 C  CB  . THR A 1 198 ? -69.427 -21.78  31.003  1    83.68  ? 368 THR D CB  1 
ATOM   1591 O  OG1 . THR A 1 198 ? -68.675 -21.832 29.794  1    82.43  ? 368 THR D OG1 1 
ATOM   1592 C  CG2 . THR A 1 198 ? -68.836 -20.753 31.951  1    78.83  ? 368 THR D CG2 1 
ATOM   1593 N  N   . GLY A 1 199 ? -69.07  -24.854 29.866  1    83.49  ? 369 GLY D N   1 
ATOM   1594 C  CA  . GLY A 1 199 ? -69.403 -25.688 28.72   1    82.86  ? 369 GLY D CA  1 
ATOM   1595 C  C   . GLY A 1 199 ? -69.223 -24.935 27.4    1    82.43  ? 369 GLY D C   1 
ATOM   1596 O  O   . GLY A 1 199 ? -69.294 -25.532 26.33   1    81.43  ? 369 GLY D O   1 
ATOM   1597 N  N   . GLN A 1 200 ? -68.975 -23.62  27.487  1    84.09  ? 370 GLN D N   1 
ATOM   1598 C  CA  . GLN A 1 200 ? -68.814 -22.752 26.328  1    85.01  ? 370 GLN D CA  1 
ATOM   1599 C  C   . GLN A 1 200 ? -67.406 -22.906 25.747  1    80.05  ? 370 GLN D C   1 
ATOM   1600 O  O   . GLN A 1 200 ? -66.49  -23.401 26.415  1    73.92  ? 370 GLN D O   1 
ATOM   1601 C  CB  . GLN A 1 200 ? -69.001 -21.287 26.737  1    90.71  ? 370 GLN D CB  1 
ATOM   1602 C  CG  . GLN A 1 200 ? -70.097 -20.56  25.971  1    97.89  ? 370 GLN D CG  1 
ATOM   1603 C  CD  . GLN A 1 200 ? -71.462 -20.934 26.503  1    109.42 ? 370 GLN D CD  1 
ATOM   1604 O  OE1 . GLN A 1 200 ? -71.766 -20.647 27.666  1    116.82 ? 370 GLN D OE1 1 
ATOM   1605 N  NE2 . GLN A 1 200 ? -72.275 -21.605 25.688  1    106.32 ? 370 GLN D NE2 1 
ATOM   1606 N  N   . SER A 1 201 ? -67.246 -22.446 24.496  1    80.21  ? 371 SER D N   1 
ATOM   1607 C  CA  . SER A 1 201 ? -65.958 -22.422 23.817  1    78.26  ? 371 SER D CA  1 
ATOM   1608 C  C   . SER A 1 201 ? -65.427 -20.995 23.674  1    77.47  ? 371 SER D C   1 
ATOM   1609 O  O   . SER A 1 201 ? -66.096 -20.014 23.996  1    80.29  ? 371 SER D O   1 
ATOM   1610 C  CB  . SER A 1 201 ? -66.03  -23.101 22.467  1    79.6   ? 371 SER D CB  1 
ATOM   1611 O  OG  . SER A 1 201 ? -66.206 -24.504 22.596  1    79.85  ? 371 SER D OG  1 
ATOM   1612 N  N   . TRP A 1 202 ? -64.181 -20.921 23.208  1    75.31  ? 372 TRP D N   1 
ATOM   1613 C  CA  . TRP A 1 202 ? -63.523 -19.741 22.67   1    71.92  ? 372 TRP D CA  1 
ATOM   1614 C  C   . TRP A 1 202 ? -64.5   -18.899 21.844  1    74.29  ? 372 TRP D C   1 
ATOM   1615 O  O   . TRP A 1 202 ? -65.043 -19.388 20.854  1    79.8   ? 372 TRP D O   1 
ATOM   1616 C  CB  . TRP A 1 202 ? -62.373 -20.282 21.808  1    69.71  ? 372 TRP D CB  1 
ATOM   1617 C  CG  . TRP A 1 202 ? -61.422 -19.277 21.218  1    67.97  ? 372 TRP D CG  1 
ATOM   1618 C  CD1 . TRP A 1 202 ? -61.22  -19.066 19.888  1    66.78  ? 372 TRP D CD1 1 
ATOM   1619 C  CD2 . TRP A 1 202 ? -60.526 -18.382 21.917  1    64.13  ? 372 TRP D CD2 1 
ATOM   1620 N  NE1 . TRP A 1 202 ? -60.276 -18.093 19.704  1    67.09  ? 372 TRP D NE1 1 
ATOM   1621 C  CE2 . TRP A 1 202 ? -59.82  -17.662 20.923  1    63.2   ? 372 TRP D CE2 1 
ATOM   1622 C  CE3 . TRP A 1 202 ? -60.247 -18.121 23.267  1    62.97  ? 372 TRP D CE3 1 
ATOM   1623 C  CZ2 . TRP A 1 202 ? -58.853 -16.71  21.235  1    56.17  ? 372 TRP D CZ2 1 
ATOM   1624 C  CZ3 . TRP A 1 202 ? -59.292 -17.172 23.577  1    59.84  ? 372 TRP D CZ3 1 
ATOM   1625 C  CH2 . TRP A 1 202 ? -58.612 -16.477 22.571  1    56.4   ? 372 TRP D CH2 1 
ATOM   1626 N  N   . PRO A 1 203 ? -64.76  -17.615 22.2    1    73.3   ? 373 PRO D N   1 
ATOM   1627 C  CA  . PRO A 1 203 ? -65.782 -16.808 21.513  1    77.12  ? 373 PRO D CA  1 
ATOM   1628 C  C   . PRO A 1 203 ? -65.384 -16.284 20.133  1    77.92  ? 373 PRO D C   1 
ATOM   1629 O  O   . PRO A 1 203 ? -64.202 -16.046 19.885  1    75.78  ? 373 PRO D O   1 
ATOM   1630 C  CB  . PRO A 1 203 ? -66.095 -15.639 22.476  1    75.95  ? 373 PRO D CB  1 
ATOM   1631 C  CG  . PRO A 1 203 ? -65.198 -15.875 23.683  1    73.87  ? 373 PRO D CG  1 
ATOM   1632 C  CD  . PRO A 1 203 ? -64.116 -16.878 23.294  1    71.24  ? 373 PRO D CD  1 
ATOM   1633 N  N   . GLU A 1 204 ? -66.383 -16.054 19.266  1    79     ? 374 GLU D N   1 
ATOM   1634 C  CA  . GLU A 1 204 ? -66.149 -15.465 17.954  1    81.07  ? 374 GLU D CA  1 
ATOM   1635 C  C   . GLU A 1 204 ? -65.431 -14.117 18.095  1    78.95  ? 374 GLU D C   1 
ATOM   1636 O  O   . GLU A 1 204 ? -64.593 -13.753 17.265  1    80.4   ? 374 GLU D O   1 
ATOM   1637 C  CB  . GLU A 1 204 ? -67.489 -15.317 17.229  1    89.08  ? 374 GLU D CB  1 
ATOM   1638 C  CG  . GLU A 1 204 ? -67.399 -14.68  15.843  1    94.36  ? 374 GLU D CG  1 
ATOM   1639 C  CD  . GLU A 1 204 ? -66.611 -15.429 14.782  1    100.08 ? 374 GLU D CD  1 
ATOM   1640 O  OE1 . GLU A 1 204 ? -66.332 -16.636 14.945  1    100.37 ? 374 GLU D OE1 1 
ATOM   1641 O  OE2 . GLU A 1 204 ? -66.248 -14.773 13.784  1    105.47 ? 374 GLU D OE2 1 
ATOM   1642 N  N   . SER A 1 205 ? -65.776 -13.376 19.154  1    72.15  ? 375 SER D N   1 
ATOM   1643 C  CA  . SER A 1 205 ? -65.317 -12.01  19.313  1    67.58  ? 375 SER D CA  1 
ATOM   1644 C  C   . SER A 1 205 ? -63.8   -11.997 19.545  1    66.42  ? 375 SER D C   1 
ATOM   1645 O  O   . SER A 1 205 ? -63.104 -11.048 19.164  1    61.93  ? 375 SER D O   1 
ATOM   1646 C  CB  . SER A 1 205 ? -66.092 -11.313 20.416  1    65.16  ? 375 SER D CB  1 
ATOM   1647 O  OG  . SER A 1 205 ? -65.653 -11.705 21.712  1    62.97  ? 375 SER D OG  1 
ATOM   1648 N  N   . LEU A 1 206 ? -63.295 -13.065 20.179  1    65.38  ? 376 LEU D N   1 
ATOM   1649 C  CA  . LEU A 1 206 ? -61.868 -13.209 20.437  1    62.76  ? 376 LEU D CA  1 
ATOM   1650 C  C   . LEU A 1 206 ? -61.154 -13.795 19.225  1    64.54  ? 376 LEU D C   1 
ATOM   1651 O  O   . LEU A 1 206 ? -60     -13.432 18.982  1    62.61  ? 376 LEU D O   1 
ATOM   1652 C  CB  . LEU A 1 206 ? -61.601 -14.049 21.677  1    58.61  ? 376 LEU D CB  1 
ATOM   1653 C  CG  . LEU A 1 206 ? -61.768 -13.309 23.002  1    58.29  ? 376 LEU D CG  1 
ATOM   1654 C  CD1 . LEU A 1 206 ? -61.667 -14.25  24.187  1    56.54  ? 376 LEU D CD1 1 
ATOM   1655 C  CD2 . LEU A 1 206 ? -60.761 -12.167 23.091  1    56.13  ? 376 LEU D CD2 1 
ATOM   1656 N  N   . VAL A 1 207 ? -61.842 -14.68  18.481  1    62.19  ? 377 VAL D N   1 
ATOM   1657 C  CA  . VAL A 1 207 ? -61.348 -15.06  17.169  1    64.99  ? 377 VAL D CA  1 
ATOM   1658 C  C   . VAL A 1 207 ? -61.077 -13.79  16.357  1    68.06  ? 377 VAL D C   1 
ATOM   1659 O  O   . VAL A 1 207 ? -59.995 -13.634 15.787  1    65.67  ? 377 VAL D O   1 
ATOM   1660 C  CB  . VAL A 1 207 ? -62.293 -16.032 16.434  1    68.78  ? 377 VAL D CB  1 
ATOM   1661 C  CG1 . VAL A 1 207 ? -61.903 -16.266 14.976  1    66.61  ? 377 VAL D CG1 1 
ATOM   1662 C  CG2 . VAL A 1 207 ? -62.366 -17.362 17.163  1    68.5   ? 377 VAL D CG2 1 
ATOM   1663 N  N   . GLN A 1 208 ? -62.049 -12.866 16.34   1    71.31  ? 378 GLN D N   1 
ATOM   1664 C  CA  . GLN A 1 208 ? -61.895 -11.618 15.601  1    73.79  ? 378 GLN D CA  1 
ATOM   1665 C  C   . GLN A 1 208 ? -60.759 -10.749 16.161  1    70.82  ? 378 GLN D C   1 
ATOM   1666 O  O   . GLN A 1 208 ? -60.108 -10.029 15.402  1    70.25  ? 378 GLN D O   1 
ATOM   1667 C  CB  . GLN A 1 208 ? -63.233 -10.885 15.467  1    75.62  ? 378 GLN D CB  1 
ATOM   1668 C  CG  . GLN A 1 208 ? -64.147 -11.436 14.379  1    83.65  ? 378 GLN D CG  1 
ATOM   1669 C  CD  . GLN A 1 208 ? -63.443 -11.717 13.063  1    89.23  ? 378 GLN D CD  1 
ATOM   1670 O  OE1 . GLN A 1 208 ? -63.66  -12.757 12.423  1    84.7   ? 378 GLN D OE1 1 
ATOM   1671 N  NE2 . GLN A 1 208 ? -62.589 -10.787 12.642  1    94.5   ? 378 GLN D NE2 1 
ATOM   1672 N  N   . LYS A 1 209 ? -60.535 -10.79  17.487  1    67.51  ? 379 LYS D N   1 
ATOM   1673 C  CA  . LYS A 1 209 ? -59.525 -9.956  18.125  1    66.17  ? 379 LYS D CA  1 
ATOM   1674 C  C   . LYS A 1 209 ? -58.124 -10.488 17.832  1    68.19  ? 379 LYS D C   1 
ATOM   1675 O  O   . LYS A 1 209 ? -57.214 -9.706  17.536  1    67.43  ? 379 LYS D O   1 
ATOM   1676 C  CB  . LYS A 1 209 ? -59.701 -9.863  19.648  1    66.21  ? 379 LYS D CB  1 
ATOM   1677 C  CG  . LYS A 1 209 ? -58.731 -8.906  20.367  1    67.14  ? 379 LYS D CG  1 
ATOM   1678 C  CD  . LYS A 1 209 ? -58.839 -8.955  21.891  1    68.34  ? 379 LYS D CD  1 
ATOM   1679 C  CE  . LYS A 1 209 ? -58.113 -7.912  22.681  1    62.38  ? 379 LYS D CE  1 
ATOM   1680 N  NZ  . LYS A 1 209 ? -58.482 -6.575  22.224  1    66.05  ? 379 LYS D NZ  1 
ATOM   1681 N  N   . THR A 1 210 ? -57.965 -11.822 17.961  1    68.35  ? 380 THR D N   1 
ATOM   1682 C  CA  . THR A 1 210 ? -56.667 -12.488 18.042  1    64.07  ? 380 THR D CA  1 
ATOM   1683 C  C   . THR A 1 210 ? -56.25  -13.117 16.714  1    62.8   ? 380 THR D C   1 
ATOM   1684 O  O   . THR A 1 210 ? -55.066 -13.369 16.498  1    61.14  ? 380 THR D O   1 
ATOM   1685 C  CB  . THR A 1 210 ? -56.681 -13.574 19.118  1    63.97  ? 380 THR D CB  1 
ATOM   1686 O  OG1 . THR A 1 210 ? -57.55  -14.605 18.643  1    69.33  ? 380 THR D OG1 1 
ATOM   1687 C  CG2 . THR A 1 210 ? -57.092 -13.024 20.471  1    60.48  ? 380 THR D CG2 1 
ATOM   1688 N  N   . GLY A 1 211 ? -57.229 -13.466 15.875  1    61.96  ? 381 GLY D N   1 
ATOM   1689 C  CA  . GLY A 1 211 ? -56.937 -14.235 14.683  1    59.25  ? 381 GLY D CA  1 
ATOM   1690 C  C   . GLY A 1 211 ? -56.807 -15.73  14.959  1    57.88  ? 381 GLY D C   1 
ATOM   1691 O  O   . GLY A 1 211 ? -56.728 -16.502 14.013  1    63.14  ? 381 GLY D O   1 
ATOM   1692 N  N   . TYR A 1 212 ? -56.815 -16.149 16.229  1    56.63  ? 382 TYR D N   1 
ATOM   1693 C  CA  . TYR A 1 212 ? -56.643 -17.561 16.552  1    60.26  ? 382 TYR D CA  1 
ATOM   1694 C  C   . TYR A 1 212 ? -57.99  -18.283 16.491  1    64.51  ? 382 TYR D C   1 
ATOM   1695 O  O   . TYR A 1 212 ? -58.966 -17.819 17.072  1    66.21  ? 382 TYR D O   1 
ATOM   1696 C  CB  . TYR A 1 212 ? -56.017 -17.788 17.937  1    59.75  ? 382 TYR D CB  1 
ATOM   1697 C  CG  . TYR A 1 212 ? -54.668 -17.127 18.199  1    56.65  ? 382 TYR D CG  1 
ATOM   1698 C  CD1 . TYR A 1 212 ? -53.694 -17.024 17.205  1    55.81  ? 382 TYR D CD1 1 
ATOM   1699 C  CD2 . TYR A 1 212 ? -54.372 -16.598 19.451  1    53.41  ? 382 TYR D CD2 1 
ATOM   1700 C  CE1 . TYR A 1 212 ? -52.475 -16.407 17.453  1    54.9   ? 382 TYR D CE1 1 
ATOM   1701 C  CE2 . TYR A 1 212 ? -53.153 -15.992 19.716  1    50.15  ? 382 TYR D CE2 1 
ATOM   1702 C  CZ  . TYR A 1 212 ? -52.205 -15.893 18.713  1    52.45  ? 382 TYR D CZ  1 
ATOM   1703 O  OH  . TYR A 1 212 ? -51.013 -15.29  18.975  1    48.98  ? 382 TYR D OH  1 
ATOM   1704 N  N   . THR A 1 213 ? -58.035 -19.444 15.821  1    67.86  ? 383 THR D N   1 
ATOM   1705 C  CA  . THR A 1 213 ? -59.199 -20.32  15.889  1    71.42  ? 383 THR D CA  1 
ATOM   1706 C  C   . THR A 1 213 ? -58.867 -21.55  16.735  1    70.26  ? 383 THR D C   1 
ATOM   1707 O  O   . THR A 1 213 ? -57.704 -21.782 17.071  1    68.8   ? 383 THR D O   1 
ATOM   1708 C  CB  . THR A 1 213 ? -59.655 -20.676 14.476  1    77.1   ? 383 THR D CB  1 
ATOM   1709 O  OG1 . THR A 1 213 ? -58.775 -21.686 13.989  1    82.73  ? 383 THR D OG1 1 
ATOM   1710 C  CG2 . THR A 1 213 ? -59.638 -19.47  13.554  1    77.7   ? 383 THR D CG2 1 
ATOM   1711 N  N   . LEU A 1 214 ? -59.898 -22.321 17.098  1    73.9   ? 384 LEU D N   1 
ATOM   1712 C  CA  . LEU A 1 214 ? -59.704 -23.561 17.843  1    76.88  ? 384 LEU D CA  1 
ATOM   1713 C  C   . LEU A 1 214 ? -58.789 -24.517 17.076  1    76.4   ? 384 LEU D C   1 
ATOM   1714 O  O   . LEU A 1 214 ? -58.007 -25.242 17.683  1    73.88  ? 384 LEU D O   1 
ATOM   1715 C  CB  . LEU A 1 214 ? -61.012 -24.245 18.239  1    77.48  ? 384 LEU D CB  1 
ATOM   1716 C  CG  . LEU A 1 214 ? -61.822 -23.568 19.347  1    75.1   ? 384 LEU D CG  1 
ATOM   1717 C  CD1 . LEU A 1 214 ? -62.78  -24.54  20.012  1    75.42  ? 384 LEU D CD1 1 
ATOM   1718 C  CD2 . LEU A 1 214 ? -60.903 -22.94  20.37   1    69.86  ? 384 LEU D CD2 1 
ATOM   1719 N  N   . GLU A 1 215 ? -58.876 -24.49  15.744  1    78.15  ? 385 GLU D N   1 
ATOM   1720 C  CA  . GLU A 1 215 ? -57.943 -25.237 14.915  1    82.53  ? 385 GLU D CA  1 
ATOM   1721 C  C   . GLU A 1 215 ? -56.502 -24.834 15.259  1    79.45  ? 385 GLU D C   1 
ATOM   1722 O  O   . GLU A 1 215 ? -55.687 -25.675 15.627  1    77.66  ? 385 GLU D O   1 
ATOM   1723 C  CB  . GLU A 1 215 ? -58.325 -25.114 13.438  1    87.22  ? 385 GLU D CB  1 
ATOM   1724 C  CG  . GLU A 1 215 ? -57.46  -25.989 12.536  1    95.86  ? 385 GLU D CG  1 
ATOM   1725 C  CD  . GLU A 1 215 ? -57.771 -25.84  11.063  1    104.07 ? 385 GLU D CD  1 
ATOM   1726 O  OE1 . GLU A 1 215 ? -58.747 -26.473 10.606  1    110.01 ? 385 GLU D OE1 1 
ATOM   1727 O  OE2 . GLU A 1 215 ? -57.051 -25.067 10.393  1    103.34 ? 385 GLU D OE2 1 
ATOM   1728 N  N   . THR A 1 216 ? -56.2   -23.533 15.184  1    74.66  ? 386 THR D N   1 
ATOM   1729 C  CA  . THR A 1 216 ? -54.836 -23.064 15.358  1    71.14  ? 386 THR D CA  1 
ATOM   1730 C  C   . THR A 1 216 ? -54.392 -23.214 16.814  1    68.9   ? 386 THR D C   1 
ATOM   1731 O  O   . THR A 1 216 ? -53.192 -23.265 17.081  1    66.44  ? 386 THR D O   1 
ATOM   1732 C  CB  . THR A 1 216 ? -54.667 -21.62  14.876  1    72.41  ? 386 THR D CB  1 
ATOM   1733 O  OG1 . THR A 1 216 ? -55.412 -20.826 15.791  1    72.97  ? 386 THR D OG1 1 
ATOM   1734 C  CG2 . THR A 1 216 ? -55.111 -21.379 13.44   1    71.34  ? 386 THR D CG2 1 
ATOM   1735 N  N   . LEU A 1 217 ? -55.346 -23.273 17.757  1    65.89  ? 387 LEU D N   1 
ATOM   1736 C  CA  . LEU A 1 217 ? -55.005 -23.445 19.164  1    61.63  ? 387 LEU D CA  1 
ATOM   1737 C  C   . LEU A 1 217 ? -54.959 -24.918 19.558  1    61.6   ? 387 LEU D C   1 
ATOM   1738 O  O   . LEU A 1 217 ? -54.79  -25.211 20.723  1    65.09  ? 387 LEU D O   1 
ATOM   1739 C  CB  . LEU A 1 217 ? -56.013 -22.737 20.064  1    59.4   ? 387 LEU D CB  1 
ATOM   1740 C  CG  . LEU A 1 217 ? -56.115 -21.221 19.929  1    58.73  ? 387 LEU D CG  1 
ATOM   1741 C  CD1 . LEU A 1 217 ? -57.333 -20.779 20.718  1    59.88  ? 387 LEU D CD1 1 
ATOM   1742 C  CD2 . LEU A 1 217 ? -54.86  -20.516 20.41   1    55.19  ? 387 LEU D CD2 1 
ATOM   1743 N  N   . LYS A 1 218 ? -55.145 -25.839 18.624  1    62.79  ? 388 LYS D N   1 
ATOM   1744 C  CA  . LYS A 1 218 ? -55.304 -27.239 18.991  1    68.24  ? 388 LYS D CA  1 
ATOM   1745 C  C   . LYS A 1 218 ? -54.021 -27.809 19.603  1    67.92  ? 388 LYS D C   1 
ATOM   1746 O  O   . LYS A 1 218 ? -54.095 -28.452 20.651  1    68.5   ? 388 LYS D O   1 
ATOM   1747 C  CB  . LYS A 1 218 ? -55.806 -28.098 17.819  1    71.24  ? 388 LYS D CB  1 
ATOM   1748 C  CG  . LYS A 1 218 ? -56.128 -29.558 18.1    1    73.62  ? 388 LYS D CG  1 
ATOM   1749 C  CD  . LYS A 1 218 ? -56.768 -30.241 16.896  1    77.89  ? 388 LYS D CD  1 
ATOM   1750 C  CE  . LYS A 1 218 ? -57.32  -31.608 17.141  1    82.24  ? 388 LYS D CE  1 
ATOM   1751 N  NZ  . LYS A 1 218 ? -58.257 -31.992 16.077  1    86.62  ? 388 LYS D NZ  1 
ATOM   1752 N  N   . PRO A 1 219 ? -52.83  -27.672 18.964  1    68.12  ? 389 PRO D N   1 
ATOM   1753 C  CA  . PRO A 1 219 ? -51.596 -28.23  19.527  1    67.98  ? 389 PRO D CA  1 
ATOM   1754 C  C   . PRO A 1 219 ? -51.413 -27.847 20.989  1    70.91  ? 389 PRO D C   1 
ATOM   1755 O  O   . PRO A 1 219 ? -51.177 -28.717 21.831  1    77.53  ? 389 PRO D O   1 
ATOM   1756 C  CB  . PRO A 1 219 ? -50.482 -27.645 18.638  1    68.01  ? 389 PRO D CB  1 
ATOM   1757 C  CG  . PRO A 1 219 ? -51.166 -27.372 17.296  1    67.39  ? 389 PRO D CG  1 
ATOM   1758 C  CD  . PRO A 1 219 ? -52.608 -27.025 17.654  1    67.39  ? 389 PRO D CD  1 
ATOM   1759 N  N   . CYS A 1 220 ? -51.55  -26.54  21.268  1    69.14  ? 390 CYS D N   1 
ATOM   1760 C  CA  . CYS A 1 220 ? -51.332 -25.994 22.595  1    63.17  ? 390 CYS D CA  1 
ATOM   1761 C  C   . CYS A 1 220 ? -52.398 -26.513 23.562  1    63.62  ? 390 CYS D C   1 
ATOM   1762 O  O   . CYS A 1 220 ? -52.108 -26.767 24.728  1    61.47  ? 390 CYS D O   1 
ATOM   1763 C  CB  . CYS A 1 220 ? -51.296 -24.473 22.524  1    63.19  ? 390 CYS D CB  1 
ATOM   1764 S  SG  . CYS A 1 220 ? -50.897 -23.68  24.102  1    61.05  ? 390 CYS D SG  1 
ATOM   1765 N  N   . LEU A 1 221 ? -53.618 -26.674 23.107  1    66.38  ? 391 LEU D N   1 
ATOM   1766 C  CA  . LEU A 1 221 ? -54.713 -27.143 23.995  1    67.91  ? 391 LEU D CA  1 
ATOM   1767 C  C   . LEU A 1 221 ? -54.52  -28.632 24.31   1    70.32  ? 391 LEU D C   1 
ATOM   1768 O  O   . LEU A 1 221 ? -54.858 -29.035 25.429  1    69.17  ? 391 LEU D O   1 
ATOM   1769 C  CB  . LEU A 1 221 ? -56.062 -26.85  23.347  1    75.1   ? 391 LEU D CB  1 
ATOM   1770 C  CG  . LEU A 1 221 ? -56.401 -25.37  23.165  1    81.45  ? 391 LEU D CG  1 
ATOM   1771 C  CD1 . LEU A 1 221 ? -57.689 -25.21  22.383  1    81.88  ? 391 LEU D CD1 1 
ATOM   1772 C  CD2 . LEU A 1 221 ? -56.492 -24.68  24.513  1    82.66  ? 391 LEU D CD2 1 
ATOM   1773 N  N   . LEU A 1 222 ? -53.986 -29.409 23.353  1    70.21  ? 392 LEU D N   1 
ATOM   1774 C  CA  . LEU A 1 222 ? -53.692 -30.811 23.62   1    72.92  ? 392 LEU D CA  1 
ATOM   1775 C  C   . LEU A 1 222 ? -52.666 -30.955 24.746  1    74.79  ? 392 LEU D C   1 
ATOM   1776 O  O   . LEU A 1 222 ? -52.822 -31.816 25.609  1    73.76  ? 392 LEU D O   1 
ATOM   1777 C  CB  . LEU A 1 222 ? -53.24  -31.55  22.361  1    74.97  ? 392 LEU D CB  1 
ATOM   1778 C  CG  . LEU A 1 222 ? -54.345 -32.032 21.408  1    78.37  ? 392 LEU D CG  1 
ATOM   1779 C  CD1 . LEU A 1 222 ? -53.74  -32.931 20.341  1    78.23  ? 392 LEU D CD1 1 
ATOM   1780 C  CD2 . LEU A 1 222 ? -55.513 -32.735 22.117  1    77.09  ? 392 LEU D CD2 1 
ATOM   1781 N  N   . ASP A 1 223 ? -51.614 -30.119 24.719  1    75.79  ? 393 ASP D N   1 
ATOM   1782 C  CA  . ASP A 1 223 ? -50.563 -30.166 25.726  1    71.14  ? 393 ASP D CA  1 
ATOM   1783 C  C   . ASP A 1 223 ? -51.151 -29.749 27.069  1    68     ? 393 ASP D C   1 
ATOM   1784 O  O   . ASP A 1 223 ? -50.886 -30.399 28.082  1    72.23  ? 393 ASP D O   1 
ATOM   1785 C  CB  . ASP A 1 223 ? -49.339 -29.339 25.348  1    66.58  ? 393 ASP D CB  1 
ATOM   1786 C  CG  . ASP A 1 223 ? -48.417 -29.939 24.299  1    66.79  ? 393 ASP D CG  1 
ATOM   1787 O  OD1 . ASP A 1 223 ? -48.22  -31.166 24.344  1    81.06  ? 393 ASP D OD1 1 
ATOM   1788 O  OD2 . ASP A 1 223 ? -47.862 -29.184 23.489  1    61.98  ? 393 ASP D OD2 1 
ATOM   1789 N  N   . LEU A 1 224 ? -51.968 -28.69  27.042  1    59.93  ? 394 LEU D N   1 
ATOM   1790 C  CA  . LEU A 1 224 ? -52.39  -28.008 28.25   1    57.56  ? 394 LEU D CA  1 
ATOM   1791 C  C   . LEU A 1 224 ? -53.424 -28.865 28.964  1    58.88  ? 394 LEU D C   1 
ATOM   1792 O  O   . LEU A 1 224 ? -53.437 -28.948 30.192  1    59.91  ? 394 LEU D O   1 
ATOM   1793 C  CB  . LEU A 1 224 ? -52.943 -26.628 27.902  1    55.22  ? 394 LEU D CB  1 
ATOM   1794 C  CG  . LEU A 1 224 ? -53.092 -25.644 29.068  1    53.51  ? 394 LEU D CG  1 
ATOM   1795 C  CD1 . LEU A 1 224 ? -51.767 -25.314 29.723  1    51.64  ? 394 LEU D CD1 1 
ATOM   1796 C  CD2 . LEU A 1 224 ? -53.787 -24.347 28.656  1    51.29  ? 394 LEU D CD2 1 
ATOM   1797 N  N   . HIS A 1 225 ? -54.301 -29.47  28.161  1    60.21  ? 395 HIS D N   1 
ATOM   1798 C  CA  . HIS A 1 225 ? -55.264 -30.44  28.641  1    62.54  ? 395 HIS D CA  1 
ATOM   1799 C  C   . HIS A 1 225 ? -54.542 -31.557 29.399  1    65.58  ? 395 HIS D C   1 
ATOM   1800 O  O   . HIS A 1 225 ? -54.992 -31.965 30.459  1    68.53  ? 395 HIS D O   1 
ATOM   1801 C  CB  . HIS A 1 225 ? -56.083 -30.967 27.46   1    63.91  ? 395 HIS D CB  1 
ATOM   1802 C  CG  . HIS A 1 225 ? -57.199 -31.913 27.808  1    66.08  ? 395 HIS D CG  1 
ATOM   1803 N  ND1 . HIS A 1 225 ? -57.838 -31.97  29.034  1    64.14  ? 395 HIS D ND1 1 
ATOM   1804 C  CD2 . HIS A 1 225 ? -57.788 -32.837 27.039  1    66.42  ? 395 HIS D CD2 1 
ATOM   1805 C  CE1 . HIS A 1 225 ? -58.766 -32.896 29.005  1    65.61  ? 395 HIS D CE1 1 
ATOM   1806 N  NE2 . HIS A 1 225 ? -58.763 -33.423 27.801  1    68.15  ? 395 HIS D NE2 1 
ATOM   1807 N  N   . GLN A 1 226 ? -53.421 -32.047 28.854  1    67.92  ? 396 GLN D N   1 
ATOM   1808 C  CA  . GLN A 1 226 ? -52.678 -33.147 29.446  1    73.28  ? 396 GLN D CA  1 
ATOM   1809 C  C   . GLN A 1 226 ? -51.983 -32.719 30.731  1    71.97  ? 396 GLN D C   1 
ATOM   1810 O  O   . GLN A 1 226 ? -51.874 -33.523 31.648  1    75.94  ? 396 GLN D O   1 
ATOM   1811 C  CB  . GLN A 1 226 ? -51.604 -33.699 28.516  1    84.13  ? 396 GLN D CB  1 
ATOM   1812 C  CG  . GLN A 1 226 ? -52.117 -34.713 27.498  1    109.15 ? 396 GLN D CG  1 
ATOM   1813 C  CD  . GLN A 1 226 ? -51.027 -35.186 26.559  1    120.64 ? 396 GLN D CD  1 
ATOM   1814 O  OE1 . GLN A 1 226 ? -50.935 -36.374 26.227  1    133.74 ? 396 GLN D OE1 1 
ATOM   1815 N  NE2 . GLN A 1 226 ? -50.194 -34.252 26.114  1    116.8  ? 396 GLN D NE2 1 
ATOM   1816 N  N   . THR A 1 227 ? -51.481 -31.48  30.77   1    66.91  ? 397 THR D N   1 
ATOM   1817 C  CA  . THR A 1 227 ? -50.792 -30.971 31.944  1    65.78  ? 397 THR D CA  1 
ATOM   1818 C  C   . THR A 1 227 ? -51.774 -30.931 33.125  1    68.24  ? 397 THR D C   1 
ATOM   1819 O  O   . THR A 1 227 ? -51.399 -31.281 34.256  1    66.12  ? 397 THR D O   1 
ATOM   1820 C  CB  . THR A 1 227 ? -50.148 -29.621 31.599  1    59.55  ? 397 THR D CB  1 
ATOM   1821 O  OG1 . THR A 1 227 ? -49.015 -29.884 30.778  1    58.2   ? 397 THR D OG1 1 
ATOM   1822 C  CG2 . THR A 1 227 ? -49.616 -28.867 32.798  1    55.52  ? 397 THR D CG2 1 
ATOM   1823 N  N   . TYR A 1 228 ? -53.034 -30.551 32.823  1    66.36  ? 398 TYR D N   1 
ATOM   1824 C  CA  . TYR A 1 228 ? -54.101 -30.315 33.789  1    68.43  ? 398 TYR D CA  1 
ATOM   1825 C  C   . TYR A 1 228 ? -54.53  -31.635 34.422  1    72.22  ? 398 TYR D C   1 
ATOM   1826 O  O   . TYR A 1 228 ? -54.759 -31.698 35.633  1    74.13  ? 398 TYR D O   1 
ATOM   1827 C  CB  . TYR A 1 228 ? -55.281 -29.634 33.081  1    67.71  ? 398 TYR D CB  1 
ATOM   1828 C  CG  . TYR A 1 228 ? -56.461 -29.184 33.937  1    70.75  ? 398 TYR D CG  1 
ATOM   1829 C  CD1 . TYR A 1 228 ? -56.38  -29.144 35.333  1    70.2   ? 398 TYR D CD1 1 
ATOM   1830 C  CD2 . TYR A 1 228 ? -57.658 -28.772 33.345  1    71.26  ? 398 TYR D CD2 1 
ATOM   1831 C  CE1 . TYR A 1 228 ? -57.452 -28.724 36.106  1    70.31  ? 398 TYR D CE1 1 
ATOM   1832 C  CE2 . TYR A 1 228 ? -58.739 -28.351 34.111  1    70.93  ? 398 TYR D CE2 1 
ATOM   1833 C  CZ  . TYR A 1 228 ? -58.632 -28.323 35.495  1    71.71  ? 398 TYR D CZ  1 
ATOM   1834 O  OH  . TYR A 1 228 ? -59.662 -27.91  36.292  1    69.81  ? 398 TYR D OH  1 
ATOM   1835 N  N   . LEU A 1 229 ? -54.666 -32.663 33.566  1    74.63  ? 399 LEU D N   1 
ATOM   1836 C  CA  . LEU A 1 229 ? -55.004 -34.039 33.91   1    74.81  ? 399 LEU D CA  1 
ATOM   1837 C  C   . LEU A 1 229 ? -53.928 -34.694 34.774  1    75.7   ? 399 LEU D C   1 
ATOM   1838 O  O   . LEU A 1 229 ? -54.24  -35.582 35.56   1    76.38  ? 399 LEU D O   1 
ATOM   1839 C  CB  . LEU A 1 229 ? -55.173 -34.84  32.621  1    74.03  ? 399 LEU D CB  1 
ATOM   1840 C  CG  . LEU A 1 229 ? -56.514 -34.712 31.899  1    73.06  ? 399 LEU D CG  1 
ATOM   1841 C  CD1 . LEU A 1 229 ? -56.384 -35.299 30.507  1    72.55  ? 399 LEU D CD1 1 
ATOM   1842 C  CD2 . LEU A 1 229 ? -57.56  -35.455 32.701  1    72.21  ? 399 LEU D CD2 1 
ATOM   1843 N  N   . ARG A 1 230 ? -52.667 -34.283 34.592  1    77.34  ? 400 ARG D N   1 
ATOM   1844 C  CA  . ARG A 1 230 ? -51.534 -34.913 35.254  1    78.93  ? 400 ARG D CA  1 
ATOM   1845 C  C   . ARG A 1 230 ? -51.052 -34.077 36.435  1    77.49  ? 400 ARG D C   1 
ATOM   1846 O  O   . ARG A 1 230 ? -50.216 -34.551 37.19   1    78.28  ? 400 ARG D O   1 
ATOM   1847 C  CB  . ARG A 1 230 ? -50.388 -35.164 34.266  1    79.94  ? 400 ARG D CB  1 
ATOM   1848 C  CG  . ARG A 1 230 ? -50.807 -36.16  33.196  1    88.92  ? 400 ARG D CG  1 
ATOM   1849 C  CD  . ARG A 1 230 ? -49.81  -36.424 32.092  1    94.2   ? 400 ARG D CD  1 
ATOM   1850 N  NE  . ARG A 1 230 ? -50.32  -37.583 31.344  1    103.65 ? 400 ARG D NE  1 
ATOM   1851 C  CZ  . ARG A 1 230 ? -50.491 -37.642 30.028  1    103.42 ? 400 ARG D CZ  1 
ATOM   1852 N  NH1 . ARG A 1 230 ? -50.128 -36.618 29.268  1    101.84 ? 400 ARG D NH1 1 
ATOM   1853 N  NH2 . ARG A 1 230 ? -51.01  -38.732 29.49   1    101.24 ? 400 ARG D NH2 1 
ATOM   1854 N  N   . ALA A 1 231 ? -51.569 -32.849 36.581  1    75.59  ? 401 ALA D N   1 
ATOM   1855 C  CA  . ALA A 1 231 ? -51.158 -31.942 37.646  1    69.96  ? 401 ALA D CA  1 
ATOM   1856 C  C   . ALA A 1 231 ? -51.096 -32.652 38.998  1    69.39  ? 401 ALA D C   1 
ATOM   1857 O  O   . ALA A 1 231 ? -50.065 -32.594 39.651  1    71.65  ? 401 ALA D O   1 
ATOM   1858 C  CB  . ALA A 1 231 ? -52.036 -30.713 37.684  1    66.66  ? 401 ALA D CB  1 
ATOM   1859 N  N   . PRO A 1 232 ? -52.157 -33.349 39.478  1    72.65  ? 402 PRO D N   1 
ATOM   1860 C  CA  . PRO A 1 232 ? -52.061 -34.091 40.74   1    71.99  ? 402 PRO D CA  1 
ATOM   1861 C  C   . PRO A 1 232 ? -50.781 -34.894 40.963  1    70.2   ? 402 PRO D C   1 
ATOM   1862 O  O   . PRO A 1 232 ? -50.339 -35.002 42.098  1    68.29  ? 402 PRO D O   1 
ATOM   1863 C  CB  . PRO A 1 232 ? -53.306 -34.973 40.727  1    73.52  ? 402 PRO D CB  1 
ATOM   1864 C  CG  . PRO A 1 232 ? -54.32  -34.153 39.961  1    73.37  ? 402 PRO D CG  1 
ATOM   1865 C  CD  . PRO A 1 232 ? -53.505 -33.434 38.882  1    71.07  ? 402 PRO D CD  1 
ATOM   1866 N  N   . GLN A 1 233 ? -50.193 -35.414 39.872  1    70.3   ? 403 GLN D N   1 
ATOM   1867 C  CA  . GLN A 1 233 ? -49.044 -36.318 39.894  1    71.77  ? 403 GLN D CA  1 
ATOM   1868 C  C   . GLN A 1 233 ? -47.734 -35.611 39.538  1    67.73  ? 403 GLN D C   1 
ATOM   1869 O  O   . GLN A 1 233 ? -46.674 -36.229 39.543  1    67.68  ? 403 GLN D O   1 
ATOM   1870 C  CB  . GLN A 1 233 ? -49.211 -37.482 38.91   1    76.31  ? 403 GLN D CB  1 
ATOM   1871 C  CG  . GLN A 1 233 ? -49.602 -38.826 39.519  1    81.93  ? 403 GLN D CG  1 
ATOM   1872 C  CD  . GLN A 1 233 ? -50.954 -38.814 40.192  1    84.38  ? 403 GLN D CD  1 
ATOM   1873 O  OE1 . GLN A 1 233 ? -51.121 -39.371 41.285  1    89.15  ? 403 GLN D OE1 1 
ATOM   1874 N  NE2 . GLN A 1 233 ? -51.934 -38.206 39.531  1    80.3   ? 403 GLN D NE2 1 
ATOM   1875 N  N   . HIS A 1 234 ? -47.794 -34.325 39.195  1    64.45  ? 404 HIS D N   1 
ATOM   1876 C  CA  . HIS A 1 234 ? -46.588 -33.619 38.818  1    59.05  ? 404 HIS D CA  1 
ATOM   1877 C  C   . HIS A 1 234 ? -45.668 -33.592 40.041  1    58.97  ? 404 HIS D C   1 
ATOM   1878 O  O   . HIS A 1 234 ? -46.147 -33.49  41.171  1    56.81  ? 404 HIS D O   1 
ATOM   1879 C  CB  . HIS A 1 234 ? -46.991 -32.25  38.262  1    59.54  ? 404 HIS D CB  1 
ATOM   1880 C  CG  . HIS A 1 234 ? -45.909 -31.572 37.483  1    62.76  ? 404 HIS D CG  1 
ATOM   1881 N  ND1 . HIS A 1 234 ? -44.695 -31.198 38.037  1    63.22  ? 404 HIS D ND1 1 
ATOM   1882 C  CD2 . HIS A 1 234 ? -45.854 -31.236 36.192  1    58.42  ? 404 HIS D CD2 1 
ATOM   1883 C  CE1 . HIS A 1 234 ? -43.94  -30.642 37.109  1    61.77  ? 404 HIS D CE1 1 
ATOM   1884 N  NE2 . HIS A 1 234 ? -44.63  -30.66  35.981  1    62.99  ? 404 HIS D NE2 1 
ATOM   1885 N  N   . ALA A 1 235 ? -44.348 -33.695 39.816  1    58.68  ? 405 ALA D N   1 
ATOM   1886 C  CA  . ALA A 1 235 ? -43.369 -33.544 40.885  1    58.66  ? 405 ALA D CA  1 
ATOM   1887 C  C   . ALA A 1 235 ? -43.51  -32.188 41.581  1    59.86  ? 405 ALA D C   1 
ATOM   1888 O  O   . ALA A 1 235 ? -43.322 -32.127 42.793  1    62.94  ? 405 ALA D O   1 
ATOM   1889 C  CB  . ALA A 1 235 ? -41.954 -33.762 40.378  1    56.08  ? 405 ALA D CB  1 
ATOM   1890 N  N   . GLN A 1 236 ? -43.856 -31.119 40.837  1    56.11  ? 406 GLN D N   1 
ATOM   1891 C  CA  . GLN A 1 236 ? -44.017 -29.782 41.41   1    55.8   ? 406 GLN D CA  1 
ATOM   1892 C  C   . GLN A 1 236 ? -45.486 -29.433 41.654  1    57.77  ? 406 GLN D C   1 
ATOM   1893 O  O   . GLN A 1 236 ? -46.274 -29.416 40.714  1    59.93  ? 406 GLN D O   1 
ATOM   1894 C  CB  . GLN A 1 236 ? -43.408 -28.686 40.54   1    51.49  ? 406 GLN D CB  1 
ATOM   1895 C  CG  . GLN A 1 236 ? -41.933 -28.475 40.815  1    48.94  ? 406 GLN D CG  1 
ATOM   1896 C  CD  . GLN A 1 236 ? -41.121 -29.652 40.35   1    58.29  ? 406 GLN D CD  1 
ATOM   1897 O  OE1 . GLN A 1 236 ? -41.277 -30.117 39.212  1    66.36  ? 406 GLN D OE1 1 
ATOM   1898 N  NE2 . GLN A 1 236 ? -40.247 -30.129 41.226  1    59.46  ? 406 GLN D NE2 1 
ATOM   1899 N  N   . GLN A 1 237 ? -45.804 -29.043 42.899  1    58.13  ? 407 GLN D N   1 
ATOM   1900 C  CA  . GLN A 1 237 ? -47.17  -28.973 43.389  1    59.34  ? 407 GLN D CA  1 
ATOM   1901 C  C   . GLN A 1 237 ? -47.551 -27.591 43.928  1    60.63  ? 407 GLN D C   1 
ATOM   1902 O  O   . GLN A 1 237 ? -48.664 -27.436 44.44   1    64.93  ? 407 GLN D O   1 
ATOM   1903 C  CB  . GLN A 1 237 ? -47.308 -29.936 44.569  1    58.8   ? 407 GLN D CB  1 
ATOM   1904 C  CG  . GLN A 1 237 ? -47.442 -31.391 44.153  1    62.3   ? 407 GLN D CG  1 
ATOM   1905 C  CD  . GLN A 1 237 ? -48.579 -31.593 43.181  1    65.28  ? 407 GLN D CD  1 
ATOM   1906 O  OE1 . GLN A 1 237 ? -49.731 -31.257 43.464  1    69.14  ? 407 GLN D OE1 1 
ATOM   1907 N  NE2 . GLN A 1 237 ? -48.263 -32.116 42.011  1    64.86  ? 407 GLN D NE2 1 
ATOM   1908 N  N   . SER A 1 238 ? -46.645 -26.607 43.851  1    54.31  ? 408 SER D N   1 
ATOM   1909 C  CA  . SER A 1 238 ? -46.868 -25.37  44.587  1    57.11  ? 408 SER D CA  1 
ATOM   1910 C  C   . SER A 1 238 ? -48.07  -24.593 44.042  1    58.87  ? 408 SER D C   1 
ATOM   1911 O  O   . SER A 1 238 ? -48.765 -23.896 44.787  1    62.39  ? 408 SER D O   1 
ATOM   1912 C  CB  . SER A 1 238 ? -45.644 -24.5   44.591  1    53.96  ? 408 SER D CB  1 
ATOM   1913 O  OG  . SER A 1 238 ? -44.623 -25.068 45.386  1    52.03  ? 408 SER D OG  1 
ATOM   1914 N  N   . ILE A 1 239 ? -48.293 -24.698 42.731  1    58.09  ? 409 ILE D N   1 
ATOM   1915 C  CA  . ILE A 1 239 ? -49.334 -23.924 42.089  1    54.19  ? 409 ILE D CA  1 
ATOM   1916 C  C   . ILE A 1 239 ? -50.686 -24.538 42.437  1    61.68  ? 409 ILE D C   1 
ATOM   1917 O  O   . ILE A 1 239 ? -51.644 -23.8   42.675  1    61.21  ? 409 ILE D O   1 
ATOM   1918 C  CB  . ILE A 1 239 ? -49.086 -23.823 40.579  1    50.12  ? 409 ILE D CB  1 
ATOM   1919 C  CG1 . ILE A 1 239 ? -47.796 -23.058 40.272  1    48.87  ? 409 ILE D CG1 1 
ATOM   1920 C  CG2 . ILE A 1 239 ? -50.27  -23.159 39.898  1    47.95  ? 409 ILE D CG2 1 
ATOM   1921 C  CD1 . ILE A 1 239 ? -47.321 -23.194 38.841  1    46.25  ? 409 ILE D CD1 1 
ATOM   1922 N  N   . ARG A 1 240 ? -50.745 -25.877 42.507  1    62.47  ? 410 ARG D N   1 
ATOM   1923 C  CA  . ARG A 1 240 ? -51.986 -26.544 42.891  1    63     ? 410 ARG D CA  1 
ATOM   1924 C  C   . ARG A 1 240 ? -52.426 -26.102 44.286  1    65.39  ? 410 ARG D C   1 
ATOM   1925 O  O   . ARG A 1 240 ? -53.613 -25.837 44.487  1    66.58  ? 410 ARG D O   1 
ATOM   1926 C  CB  . ARG A 1 240 ? -51.9   -28.075 42.862  1    61.96  ? 410 ARG D CB  1 
ATOM   1927 C  CG  . ARG A 1 240 ? -51.948 -28.674 41.467  1    60.59  ? 410 ARG D CG  1 
ATOM   1928 C  CD  . ARG A 1 240 ? -52.088 -30.178 41.462  1    66.55  ? 410 ARG D CD  1 
ATOM   1929 N  NE  . ARG A 1 240 ? -53.444 -30.646 41.794  1    67.85  ? 410 ARG D NE  1 
ATOM   1930 C  CZ  . ARG A 1 240 ? -53.775 -31.43  42.81   1    65.4   ? 410 ARG D CZ  1 
ATOM   1931 N  NH1 . ARG A 1 240 ? -54.995 -31.926 42.863  1    68.73  ? 410 ARG D NH1 1 
ATOM   1932 N  NH2 . ARG A 1 240 ? -52.885 -31.764 43.722  1    61.71  ? 410 ARG D NH2 1 
ATOM   1933 N  N   . GLU A 1 241 ? -51.468 -26.061 45.23   1    66.4   ? 411 GLU D N   1 
ATOM   1934 C  CA  . GLU A 1 241 ? -51.709 -25.683 46.617  1    65.94  ? 411 GLU D CA  1 
ATOM   1935 C  C   . GLU A 1 241 ? -52.153 -24.226 46.666  1    65.92  ? 411 GLU D C   1 
ATOM   1936 O  O   . GLU A 1 241 ? -53.067 -23.868 47.411  1    71.66  ? 411 GLU D O   1 
ATOM   1937 C  CB  . GLU A 1 241 ? -50.444 -25.769 47.472  1    64.43  ? 411 GLU D CB  1 
ATOM   1938 C  CG  . GLU A 1 241 ? -50.054 -27.192 47.856  1    72.34  ? 411 GLU D CG  1 
ATOM   1939 C  CD  . GLU A 1 241 ? -51.23  -28.016 48.365  1    80.81  ? 411 GLU D CD  1 
ATOM   1940 O  OE1 . GLU A 1 241 ? -51.781 -27.636 49.423  1    83.83  ? 411 GLU D OE1 1 
ATOM   1941 O  OE2 . GLU A 1 241 ? -51.613 -29.019 47.713  1    76.42  ? 411 GLU D OE2 1 
ATOM   1942 N  N   . LYS A 1 242 ? -51.498 -23.403 45.846  1    56.26  ? 412 LYS D N   1 
ATOM   1943 C  CA  . LYS A 1 242 ? -51.783 -21.982 45.856  1    57.04  ? 412 LYS D CA  1 
ATOM   1944 C  C   . LYS A 1 242 ? -53.246 -21.753 45.474  1    58.7   ? 412 LYS D C   1 
ATOM   1945 O  O   . LYS A 1 242 ? -53.888 -20.889 46.065  1    64.84  ? 412 LYS D O   1 
ATOM   1946 C  CB  . LYS A 1 242 ? -50.745 -21.297 44.954  1    51.83  ? 412 LYS D CB  1 
ATOM   1947 C  CG  . LYS A 1 242 ? -51.103 -19.933 44.404  1    47.18  ? 412 LYS D CG  1 
ATOM   1948 C  CD  . LYS A 1 242 ? -49.958 -19.287 43.643  1    45.55  ? 412 LYS D CD  1 
ATOM   1949 C  CE  . LYS A 1 242 ? -50.307 -18.073 42.844  1    43.98  ? 412 LYS D CE  1 
ATOM   1950 N  NZ  . LYS A 1 242 ? -49.208 -17.65  41.971  1    41.77  ? 412 LYS D NZ  1 
ATOM   1951 N  N   . TYR A 1 243 ? -53.747 -22.547 44.511  1    57.63  ? 413 TYR D N   1 
ATOM   1952 C  CA  . TYR A 1 243 ? -55.037 -22.349 43.858  1    59.71  ? 413 TYR D CA  1 
ATOM   1953 C  C   . TYR A 1 243 ? -56.121 -23.247 44.466  1    64.03  ? 413 TYR D C   1 
ATOM   1954 O  O   . TYR A 1 243 ? -57.226 -23.341 43.924  1    63.62  ? 413 TYR D O   1 
ATOM   1955 C  CB  . TYR A 1 243 ? -54.954 -22.555 42.341  1    57.68  ? 413 TYR D CB  1 
ATOM   1956 C  CG  . TYR A 1 243 ? -54.395 -21.38  41.556  1    58.43  ? 413 TYR D CG  1 
ATOM   1957 C  CD1 . TYR A 1 243 ? -53.022 -21.14  41.498  1    60.59  ? 413 TYR D CD1 1 
ATOM   1958 C  CD2 . TYR A 1 243 ? -55.233 -20.502 40.867  1    58.24  ? 413 TYR D CD2 1 
ATOM   1959 C  CE1 . TYR A 1 243 ? -52.494 -20.075 40.774  1    54.98  ? 413 TYR D CE1 1 
ATOM   1960 C  CE2 . TYR A 1 243 ? -54.722 -19.426 40.155  1    54.52  ? 413 TYR D CE2 1 
ATOM   1961 C  CZ  . TYR A 1 243 ? -53.351 -19.22  40.11   1    55.6   ? 413 TYR D CZ  1 
ATOM   1962 O  OH  . TYR A 1 243 ? -52.81  -18.174 39.433  1    59.98  ? 413 TYR D OH  1 
ATOM   1963 N  N   . LYS A 1 244 ? -55.804 -23.907 45.589  1    66.31  ? 414 LYS D N   1 
ATOM   1964 C  CA  . LYS A 1 244 ? -56.813 -24.549 46.416  1    70     ? 414 LYS D CA  1 
ATOM   1965 C  C   . LYS A 1 244 ? -57.474 -23.511 47.321  1    75.43  ? 414 LYS D C   1 
ATOM   1966 O  O   . LYS A 1 244 ? -58.653 -23.651 47.683  1    76.62  ? 414 LYS D O   1 
ATOM   1967 C  CB  . LYS A 1 244 ? -56.2   -25.593 47.351  1    71.69  ? 414 LYS D CB  1 
ATOM   1968 C  CG  . LYS A 1 244 ? -55.632 -26.817 46.669  1    75.65  ? 414 LYS D CG  1 
ATOM   1969 C  CD  . LYS A 1 244 ? -55.075 -27.853 47.644  1    81.27  ? 414 LYS D CD  1 
ATOM   1970 C  CE  . LYS A 1 244 ? -54.719 -29.137 46.944  1    81.2   ? 414 LYS D CE  1 
ATOM   1971 N  NZ  . LYS A 1 244 ? -54.295 -30.188 47.866  1    79.9   ? 414 LYS D NZ  1 
ATOM   1972 N  N   A ASN A 1 245 ? -56.705 -22.474 47.67   0.5  73.02  ? 415 ASN D N   1 
ATOM   1973 N  N   B ASN A 1 245 ? -56.7   -22.475 47.692  0.5  75.03  ? 415 ASN D N   1 
ATOM   1974 C  CA  A ASN A 1 245 ? -57.14  -21.506 48.661  0.5  75.01  ? 415 ASN D CA  1 
ATOM   1975 C  CA  B ASN A 1 245 ? -57.145 -21.481 48.66   0.5  78.67  ? 415 ASN D CA  1 
ATOM   1976 C  C   A ASN A 1 245 ? -58.398 -20.795 48.159  0.5  75.7   ? 415 ASN D C   1 
ATOM   1977 C  C   B ASN A 1 245 ? -58.423 -20.814 48.153  0.5  77.63  ? 415 ASN D C   1 
ATOM   1978 O  O   A ASN A 1 245 ? -58.626 -20.7   46.951  0.5  72.86  ? 415 ASN D O   1 
ATOM   1979 O  O   B ASN A 1 245 ? -58.682 -20.765 46.949  0.5  74.35  ? 415 ASN D O   1 
ATOM   1980 C  CB  A ASN A 1 245 ? -55.975 -20.629 49.112  0.5  71.89  ? 415 ASN D CB  1 
ATOM   1981 C  CB  B ASN A 1 245 ? -56.023 -20.53  49.086  0.5  79.58  ? 415 ASN D CB  1 
ATOM   1982 C  CG  A ASN A 1 245 ? -54.841 -21.436 49.704  0.5  69.55  ? 415 ASN D CG  1 
ATOM   1983 C  CG  B ASN A 1 245 ? -56.453 -19.49  50.103  0.5  81.32  ? 415 ASN D CG  1 
ATOM   1984 O  OD1 A ASN A 1 245 ? -55.067 -22.296 50.566  0.5  68.53  ? 415 ASN D OD1 1 
ATOM   1985 O  OD1 B ASN A 1 245 ? -57.265 -19.776 50.995  0.5  83.87  ? 415 ASN D OD1 1 
ATOM   1986 N  ND2 A ASN A 1 245 ? -53.624 -21.189 49.242  0.5  65.62  ? 415 ASN D ND2 1 
ATOM   1987 N  ND2 B ASN A 1 245 ? -55.927 -18.277 49.987  0.5  79.37  ? 415 ASN D ND2 1 
ATOM   1988 N  N   . SER A 1 246 ? -59.22  -20.334 49.114  1    78.33  ? 416 SER D N   1 
ATOM   1989 C  CA  . SER A 1 246 ? -60.389 -19.503 48.86   1    75.08  ? 416 SER D CA  1 
ATOM   1990 C  C   . SER A 1 246 ? -60.114 -18.398 47.821  1    73.11  ? 416 SER D C   1 
ATOM   1991 O  O   . SER A 1 246 ? -60.85  -18.31  46.848  1    69.45  ? 416 SER D O   1 
ATOM   1992 C  CB  . SER A 1 246 ? -60.936 -18.98  50.169  1    71.75  ? 416 SER D CB  1 
ATOM   1993 O  OG  . SER A 1 246 ? -61.68  -17.787 49.974  1    69.33  ? 416 SER D OG  1 
ATOM   1994 N  N   . LYS A 1 247 ? -59.028 -17.616 47.986  1    71.33  ? 417 LYS D N   1 
ATOM   1995 C  CA  . LYS A 1 247 ? -58.712 -16.451 47.164  1    69.68  ? 417 LYS D CA  1 
ATOM   1996 C  C   . LYS A 1 247 ? -58.938 -16.709 45.671  1    71.36  ? 417 LYS D C   1 
ATOM   1997 O  O   . LYS A 1 247 ? -59.456 -15.832 44.978  1    65.47  ? 417 LYS D O   1 
ATOM   1998 C  CB  . LYS A 1 247 ? -57.294 -15.958 47.477  1    69.21  ? 417 LYS D CB  1 
ATOM   1999 C  CG  . LYS A 1 247 ? -56.61  -15.149 46.372  1    71.63  ? 417 LYS D CG  1 
ATOM   2000 C  CD  . LYS A 1 247 ? -55.34  -14.409 46.787  1    77.67  ? 417 LYS D CD  1 
ATOM   2001 C  CE  . LYS A 1 247 ? -54.599 -15.188 47.842  1    93.61  ? 417 LYS D CE  1 
ATOM   2002 N  NZ  . LYS A 1 247 ? -53.261 -14.653 48.113  1    98.97  ? 417 LYS D NZ  1 
ATOM   2003 N  N   . TYR A 1 248 ? -58.522 -17.895 45.182  1    75.57  ? 418 TYR D N   1 
ATOM   2004 C  CA  . TYR A 1 248 ? -58.657 -18.285 43.781  1    73.45  ? 418 TYR D CA  1 
ATOM   2005 C  C   . TYR A 1 248 ? -59.829 -19.258 43.577  1    74.16  ? 418 TYR D C   1 
ATOM   2006 O  O   . TYR A 1 248 ? -59.816 -20.044 42.626  1    74.75  ? 418 TYR D O   1 
ATOM   2007 C  CB  . TYR A 1 248 ? -57.352 -18.867 43.22   1    66.91  ? 418 TYR D CB  1 
ATOM   2008 C  CG  . TYR A 1 248 ? -56.123 -17.991 43.403  1    65.91  ? 418 TYR D CG  1 
ATOM   2009 C  CD1 . TYR A 1 248 ? -55.883 -16.902 42.562  1    63.72  ? 418 TYR D CD1 1 
ATOM   2010 C  CD2 . TYR A 1 248 ? -55.204 -18.259 44.417  1    64.74  ? 418 TYR D CD2 1 
ATOM   2011 C  CE1 . TYR A 1 248 ? -54.769 -16.093 42.732  1    62.09  ? 418 TYR D CE1 1 
ATOM   2012 C  CE2 . TYR A 1 248 ? -54.095 -17.449 44.601  1    64.17  ? 418 TYR D CE2 1 
ATOM   2013 C  CZ  . TYR A 1 248 ? -53.882 -16.362 43.763  1    65.28  ? 418 TYR D CZ  1 
ATOM   2014 O  OH  . TYR A 1 248 ? -52.781 -15.572 43.958  1    67.13  ? 418 TYR D OH  1 
ATOM   2015 N  N   . HIS A 1 249 ? -60.827 -19.216 44.474  1    72.99  ? 419 HIS D N   1 
ATOM   2016 C  CA  . HIS A 1 249 ? -62.115 -19.901 44.322  1    75.53  ? 419 HIS D CA  1 
ATOM   2017 C  C   . HIS A 1 249 ? -62.012 -21.429 44.403  1    73.3   ? 419 HIS D C   1 
ATOM   2018 O  O   . HIS A 1 249 ? -62.997 -22.122 44.149  1    73.94  ? 419 HIS D O   1 
ATOM   2019 C  CB  . HIS A 1 249 ? -62.918 -19.423 43.097  1    79.13  ? 419 HIS D CB  1 
ATOM   2020 C  CG  . HIS A 1 249 ? -63.298 -17.971 43.13   1    89.7   ? 419 HIS D CG  1 
ATOM   2021 N  ND1 . HIS A 1 249 ? -64.484 -17.509 43.662  1    97.21  ? 419 HIS D ND1 1 
ATOM   2022 C  CD2 . HIS A 1 249 ? -62.638 -16.864 42.704  1    89.64  ? 419 HIS D CD2 1 
ATOM   2023 C  CE1 . HIS A 1 249 ? -64.522 -16.181 43.564  1    101.19 ? 419 HIS D CE1 1 
ATOM   2024 N  NE2 . HIS A 1 249 ? -63.417 -15.767 42.968  1    90.4   ? 419 HIS D NE2 1 
ATOM   2025 N  N   . GLY A 1 250 ? -60.831 -21.95  44.757  1    70.54  ? 420 GLY D N   1 
ATOM   2026 C  CA  . GLY A 1 250 ? -60.618 -23.378 44.94   1    70.7   ? 420 GLY D CA  1 
ATOM   2027 C  C   . GLY A 1 250 ? -60.513 -24.164 43.631  1    70.74  ? 420 GLY D C   1 
ATOM   2028 O  O   . GLY A 1 250 ? -60.773 -25.365 43.638  1    79.31  ? 420 GLY D O   1 
ATOM   2029 N  N   . VAL A 1 251 ? -60.071 -23.525 42.543  1    65.17  ? 421 VAL D N   1 
ATOM   2030 C  CA  . VAL A 1 251 ? -60.26  -24.061 41.201  1    65.16  ? 421 VAL D CA  1 
ATOM   2031 C  C   . VAL A 1 251 ? -59.377 -25.287 40.945  1    66.47  ? 421 VAL D C   1 
ATOM   2032 O  O   . VAL A 1 251 ? -59.754 -26.165 40.158  1    69.95  ? 421 VAL D O   1 
ATOM   2033 C  CB  . VAL A 1 251 ? -60.103 -23.007 40.089  1    62     ? 421 VAL D CB  1 
ATOM   2034 C  CG1 . VAL A 1 251 ? -61.208 -21.962 40.152  1    61.89  ? 421 VAL D CG1 1 
ATOM   2035 C  CG2 . VAL A 1 251 ? -58.729 -22.349 40.102  1    58.14  ? 421 VAL D CG2 1 
ATOM   2036 N  N   . SER A 1 252 ? -58.216 -25.353 41.612  1    64.22  ? 422 SER D N   1 
ATOM   2037 C  CA  . SER A 1 252 ? -57.308 -26.483 41.452  1    65.44  ? 422 SER D CA  1 
ATOM   2038 C  C   . SER A 1 252 ? -57.938 -27.794 41.939  1    69.14  ? 422 SER D C   1 
ATOM   2039 O  O   . SER A 1 252 ? -57.449 -28.864 41.587  1    67.57  ? 422 SER D O   1 
ATOM   2040 C  CB  . SER A 1 252 ? -55.966 -26.239 42.106  1    60.97  ? 422 SER D CB  1 
ATOM   2041 O  OG  . SER A 1 252 ? -56.086 -26.254 43.517  1    64.59  ? 422 SER D OG  1 
ATOM   2042 N  N   . LEU A 1 253 ? -59.009 -27.693 42.743  1    72.38  ? 423 LEU D N   1 
ATOM   2043 C  CA  . LEU A 1 253 ? -59.752 -28.836 43.257  1    78.2   ? 423 LEU D CA  1 
ATOM   2044 C  C   . LEU A 1 253 ? -60.831 -29.311 42.277  1    79.42  ? 423 LEU D C   1 
ATOM   2045 O  O   . LEU A 1 253 ? -61.511 -30.291 42.57   1    82.88  ? 423 LEU D O   1 
ATOM   2046 C  CB  . LEU A 1 253 ? -60.394 -28.475 44.599  1    80.82  ? 423 LEU D CB  1 
ATOM   2047 C  CG  . LEU A 1 253 ? -59.47  -28.213 45.797  1    82.69  ? 423 LEU D CG  1 
ATOM   2048 C  CD1 . LEU A 1 253 ? -60.327 -27.68  46.943  1    82.24  ? 423 LEU D CD1 1 
ATOM   2049 C  CD2 . LEU A 1 253 ? -58.697 -29.442 46.272  1    81.82  ? 423 LEU D CD2 1 
ATOM   2050 N  N   . LEU A 1 254 ? -61.029 -28.605 41.152  1    77.21  ? 424 LEU D N   1 
ATOM   2051 C  CA  . LEU A 1 254 ? -62.063 -28.961 40.186  1    76.69  ? 424 LEU D CA  1 
ATOM   2052 C  C   . LEU A 1 254 ? -61.605 -30.151 39.347  1    79.19  ? 424 LEU D C   1 
ATOM   2053 O  O   . LEU A 1 254 ? -60.414 -30.326 39.106  1    78.49  ? 424 LEU D O   1 
ATOM   2054 C  CB  . LEU A 1 254 ? -62.501 -27.782 39.313  1    73.32  ? 424 LEU D CB  1 
ATOM   2055 C  CG  . LEU A 1 254 ? -63.377 -26.712 39.988  1    73.81  ? 424 LEU D CG  1 
ATOM   2056 C  CD1 . LEU A 1 254 ? -63.509 -25.449 39.136  1    69.32  ? 424 LEU D CD1 1 
ATOM   2057 C  CD2 . LEU A 1 254 ? -64.763 -27.187 40.468  1    78.46  ? 424 LEU D CD2 1 
ATOM   2058 N  N   . ASN A 1 255 ? -62.566 -30.976 38.915  1    85.69  ? 425 ASN D N   1 
ATOM   2059 C  CA  . ASN A 1 255 ? -62.276 -32.129 38.077  1    88.63  ? 425 ASN D CA  1 
ATOM   2060 C  C   . ASN A 1 255 ? -62.124 -31.672 36.628  1    87.46  ? 425 ASN D C   1 
ATOM   2061 O  O   . ASN A 1 255 ? -63.08  -31.145 36.056  1    91.27  ? 425 ASN D O   1 
ATOM   2062 C  CB  . ASN A 1 255 ? -63.295 -33.25  38.268  1    89.05  ? 425 ASN D CB  1 
ATOM   2063 C  CG  . ASN A 1 255 ? -63.252 -33.786 39.68   1    92.14  ? 425 ASN D CG  1 
ATOM   2064 O  OD1 . ASN A 1 255 ? -64.296 -33.909 40.325  1    94.16  ? 425 ASN D OD1 1 
ATOM   2065 N  ND2 . ASN A 1 255 ? -62.068 -34.099 40.191  1    91.11  ? 425 ASN D ND2 1 
ATOM   2066 N  N   . PRO A 1 256 ? -60.94  -31.884 35.995  1    77.92  ? 426 PRO D N   1 
ATOM   2067 C  CA  . PRO A 1 256 ? -60.769 -31.564 34.577  1    74.89  ? 426 PRO D CA  1 
ATOM   2068 C  C   . PRO A 1 256 ? -61.683 -32.44  33.707  1    80.07  ? 426 PRO D C   1 
ATOM   2069 O  O   . PRO A 1 256 ? -61.98  -33.589 34.054  1    81.61  ? 426 PRO D O   1 
ATOM   2070 C  CB  . PRO A 1 256 ? -59.269 -31.836 34.356  1    71.58  ? 426 PRO D CB  1 
ATOM   2071 C  CG  . PRO A 1 256 ? -58.918 -32.895 35.388  1    73.52  ? 426 PRO D CG  1 
ATOM   2072 C  CD  . PRO A 1 256 ? -59.75  -32.514 36.596  1    74.12  ? 426 PRO D CD  1 
ATOM   2073 N  N   . PRO A 1 257 ? -62.166 -31.931 32.547  1    80.89  ? 427 PRO D N   1 
ATOM   2074 C  CA  . PRO A 1 257 ? -63.016 -32.729 31.652  1    83.93  ? 427 PRO D CA  1 
ATOM   2075 C  C   . PRO A 1 257 ? -62.16  -33.803 30.988  1    87.2   ? 427 PRO D C   1 
ATOM   2076 O  O   . PRO A 1 257 ? -60.982 -33.567 30.737  1    84.54  ? 427 PRO D O   1 
ATOM   2077 C  CB  . PRO A 1 257 ? -63.485 -31.664 30.637  1    83     ? 427 PRO D CB  1 
ATOM   2078 C  CG  . PRO A 1 257 ? -62.342 -30.653 30.582  1    78.5   ? 427 PRO D CG  1 
ATOM   2079 C  CD  . PRO A 1 257 ? -61.853 -30.589 32.015  1    77.23  ? 427 PRO D CD  1 
ATOM   2080 N  N   . GLU A 1 258 ? -62.739 -34.981 30.784  1    95.17  ? 428 GLU D N   1 
ATOM   2081 C  CA  . GLU A 1 258 ? -61.949 -36.112 30.246  1    101.29 ? 428 GLU D CA  1 
ATOM   2082 C  C   . GLU A 1 258 ? -61.621 -35.859 28.773  1    100.48 ? 428 GLU D C   1 
ATOM   2083 O  O   . GLU A 1 258 ? -60.621 -36.422 28.287  1    96.86  ? 428 GLU D O   1 
ATOM   2084 C  CB  . GLU A 1 258 ? -62.766 -37.384 30.443  1    114.46 ? 428 GLU D CB  1 
ATOM   2085 C  CG  . GLU A 1 258 ? -62.94  -37.757 31.912  1    121.59 ? 428 GLU D CG  1 
ATOM   2086 C  CD  . GLU A 1 258 ? -63.81  -38.98  32.141  1    125.77 ? 428 GLU D CD  1 
ATOM   2087 O  OE1 . GLU A 1 258 ? -64.444 -39.442 31.169  1    118.45 ? 428 GLU D OE1 1 
ATOM   2088 O  OE2 . GLU A 1 258 ? -63.851 -39.471 33.288  1    126.31 ? 428 GLU D OE2 1 
ATOM   2089 N  N   . THR A 1 259 ? -62.427 -35.042 28.102  1    101.32 ? 429 THR D N   1 
ATOM   2090 C  CA  . THR A 1 259 ? -62.188 -34.829 26.669  1    102.7  ? 429 THR D CA  1 
ATOM   2091 C  C   . THR A 1 259 ? -62.744 -33.498 26.23   1    101.62 ? 429 THR D C   1 
ATOM   2092 O  O   . THR A 1 259 ? -63.479 -32.873 27.011  1    99.41  ? 429 THR D O   1 
ATOM   2093 C  CB  . THR A 1 259 ? -62.817 -35.983 25.892  1    106.64 ? 429 THR D CB  1 
ATOM   2094 O  OG1 . THR A 1 259 ? -62.509 -35.722 24.527  1    109.28 ? 429 THR D OG1 1 
ATOM   2095 C  CG2 . THR A 1 259 ? -64.321 -36.061 26.08   1    104.42 ? 429 THR D CG2 1 
ATOM   2096 N  N   . LEU A 1 260 ? -62.386 -33.071 25.022  1    103.43 ? 430 LEU D N   1 
ATOM   2097 C  CA  . LEU A 1 260 ? -62.922 -31.818 24.443  1    104.64 ? 430 LEU D CA  1 
ATOM   2098 C  C   . LEU A 1 260 ? -63.116 -32.067 22.943  1    114.53 ? 430 LEU D C   1 
ATOM   2099 O  O   . LEU A 1 260 ? -62.142 -32.499 22.306  1    128.16 ? 430 LEU D O   1 
ATOM   2100 C  CB  . LEU A 1 260 ? -61.945 -30.674 24.681  1    96.42  ? 430 LEU D CB  1 
ATOM   2101 C  CG  . LEU A 1 260 ? -60.561 -30.816 24.043  1    92.55  ? 430 LEU D CG  1 
ATOM   2102 C  CD1 . LEU A 1 260 ? -60.621 -30.444 22.576  1    87.94  ? 430 LEU D CD1 1 
ATOM   2103 C  CD2 . LEU A 1 260 ? -59.558 -29.951 24.781  1    84.89  ? 430 LEU D CD2 1 
ATOM   2104 N  N   . ASN A 1 261 ? -64.306 -31.801 22.403  1    114.51 ? 431 ASN D N   1 
ATOM   2105 C  CA  . ASN A 1 261 ? -64.53  -31.924 20.936  1    113.12 ? 431 ASN D CA  1 
ATOM   2106 C  C   . ASN A 1 261 ? -63.262 -31.494 20.19   1    108.96 ? 431 ASN D C   1 
ATOM   2107 O  O   . ASN A 1 261 ? -62.978 -32.091 19.131  1    102.79 ? 431 ASN D O   1 
ATOM   2108 C  CB  . ASN A 1 261 ? -65.729 -31.09  20.505  1    115.94 ? 431 ASN D CB  1 
ATOM   2109 C  CG  . ASN A 1 261 ? -65.951 -31.109 19.012  1    112.57 ? 431 ASN D CG  1 
ATOM   2110 O  OD1 . ASN A 1 261 ? -66.179 -30.057 18.405  1    117.46 ? 431 ASN D OD1 1 
ATOM   2111 N  ND2 . ASN A 1 261 ? -65.898 -32.286 18.405  1    109    ? 431 ASN D ND2 1 
ATOM   2112 N  N   . GLY B 2 1   ? -21.475 -6.728  23.734  1    98.74  ? -3  GLY A N   1 
ATOM   2113 C  CA  . GLY B 2 1   ? -22.1   -7.831  24.484  1    89.81  ? -3  GLY A CA  1 
ATOM   2114 C  C   . GLY B 2 1   ? -22.051 -7.564  25.988  1    93.41  ? -3  GLY A C   1 
ATOM   2115 O  O   . GLY B 2 1   ? -21.53  -6.537  26.425  1    89.69  ? -3  GLY A O   1 
ATOM   2116 N  N   . PRO B 2 2   ? -22.557 -8.513  26.814  1    100.55 ? -2  PRO A N   1 
ATOM   2117 C  CA  . PRO B 2 2   ? -22.834 -8.267  28.239  1    97.46  ? -2  PRO A CA  1 
ATOM   2118 C  C   . PRO B 2 2   ? -21.737 -8.107  29.301  1    88.03  ? -2  PRO A C   1 
ATOM   2119 O  O   . PRO B 2 2   ? -22.003 -7.54   30.358  1    85.24  ? -2  PRO A O   1 
ATOM   2120 C  CB  . PRO B 2 2   ? -23.72  -9.503  28.542  1    102.38 ? -2  PRO A CB  1 
ATOM   2121 C  CG  . PRO B 2 2   ? -23.091 -10.616 27.721  1    100.09 ? -2  PRO A CG  1 
ATOM   2122 C  CD  . PRO B 2 2   ? -22.882 -9.895  26.397  1    103.28 ? -2  PRO A CD  1 
ATOM   2123 N  N   . GLY B 2 3   ? -20.521 -8.616  29.036  1    81.93  ? -1  GLY A N   1 
ATOM   2124 C  CA  . GLY B 2 3   ? -19.536 -8.928  30.067  1    77.32  ? -1  GLY A CA  1 
ATOM   2125 C  C   . GLY B 2 3   ? -18.662 -7.744  30.485  1    76.73  ? -1  GLY A C   1 
ATOM   2126 O  O   . GLY B 2 3   ? -18.596 -6.726  29.801  1    75.35  ? -1  GLY A O   1 
ATOM   2127 N  N   . SER B 2 4   ? -18.026 -7.888  31.655  1    85.93  ? 0   SER A N   1 
ATOM   2128 C  CA  . SER B 2 4   ? -16.975 -7.016  32.172  1    92.35  ? 0   SER A CA  1 
ATOM   2129 C  C   . SER B 2 4   ? -15.892 -7.9    32.791  1    92.03  ? 0   SER A C   1 
ATOM   2130 O  O   . SER B 2 4   ? -16.102 -9.099  32.961  1    97.31  ? 0   SER A O   1 
ATOM   2131 C  CB  . SER B 2 4   ? -17.491 -6.052  33.208  1    87.69  ? 0   SER A CB  1 
ATOM   2132 O  OG  . SER B 2 4   ? -18.838 -5.691  32.966  1    88.53  ? 0   SER A OG  1 
ATOM   2133 N  N   . MET B 2 5   ? -14.75  -7.31   33.16   1    86.29  ? 1   MET A N   1 
ATOM   2134 C  CA  . MET B 2 5   ? -13.649 -8.138  33.615  1    76.17  ? 1   MET A CA  1 
ATOM   2135 C  C   . MET B 2 5   ? -13.793 -8.45   35.087  1    74.96  ? 1   MET A C   1 
ATOM   2136 O  O   . MET B 2 5   ? -13.187 -9.403  35.547  1    81.74  ? 1   MET A O   1 
ATOM   2137 C  CB  . MET B 2 5   ? -12.286 -7.509  33.335  1    73.84  ? 1   MET A CB  1 
ATOM   2138 C  CG  . MET B 2 5   ? -11.995 -7.462  31.855  1    75.26  ? 1   MET A CG  1 
ATOM   2139 S  SD  . MET B 2 5   ? -12.437 -8.946  30.92   1    73.13  ? 1   MET A SD  1 
ATOM   2140 C  CE  . MET B 2 5   ? -11.194 -10.06  31.585  1    70.15  ? 1   MET A CE  1 
ATOM   2141 N  N   . GLU B 2 6   ? -14.595 -7.66   35.798  1    77.37  ? 2   GLU A N   1 
ATOM   2142 C  CA  . GLU B 2 6   ? -14.738 -7.845  37.234  1    84.33  ? 2   GLU A CA  1 
ATOM   2143 C  C   . GLU B 2 6   ? -15.482 -9.148  37.524  1    75.49  ? 2   GLU A C   1 
ATOM   2144 O  O   . GLU B 2 6   ? -15.337 -9.685  38.615  1    75.6   ? 2   GLU A O   1 
ATOM   2145 C  CB  . GLU B 2 6   ? -15.3   -6.637  37.997  1    96.64  ? 2   GLU A CB  1 
ATOM   2146 C  CG  . GLU B 2 6   ? -16.355 -5.854  37.213  1    113.1  ? 2   GLU A CG  1 
ATOM   2147 C  CD  . GLU B 2 6   ? -15.808 -4.706  36.377  1    122.98 ? 2   GLU A CD  1 
ATOM   2148 O  OE1 . GLU B 2 6   ? -15.687 -4.81   35.128  1    111.78 ? 2   GLU A OE1 1 
ATOM   2149 O  OE2 . GLU B 2 6   ? -15.537 -3.661  37.009  1    142.41 ? 2   GLU A OE2 1 
ATOM   2150 N  N   . ASN B 2 7   ? -16.241 -9.665  36.544  1    70.14  ? 3   ASN A N   1 
ATOM   2151 C  CA  . ASN B 2 7   ? -16.993 -10.896 36.744  1    68.12  ? 3   ASN A CA  1 
ATOM   2152 C  C   . ASN B 2 7   ? -16.173 -12.125 36.364  1    65.94  ? 3   ASN A C   1 
ATOM   2153 O  O   . ASN B 2 7   ? -16.716 -13.215 36.435  1    71.98  ? 3   ASN A O   1 
ATOM   2154 C  CB  . ASN B 2 7   ? -18.313 -10.965 35.974  1    67.99  ? 3   ASN A CB  1 
ATOM   2155 C  CG  . ASN B 2 7   ? -19.327 -9.934  36.416  1    74.29  ? 3   ASN A CG  1 
ATOM   2156 O  OD1 . ASN B 2 7   ? -19.512 -9.667  37.621  1    74.44  ? 3   ASN A OD1 1 
ATOM   2157 N  ND2 . ASN B 2 7   ? -19.984 -9.334  35.434  1    72.7   ? 3   ASN A ND2 1 
ATOM   2158 N  N   . PHE B 2 8   ? -14.92  -11.972 35.9    1    61.4   ? 4   PHE A N   1 
ATOM   2159 C  CA  . PHE B 2 8   ? -14.069 -13.121 35.623  1    56.8   ? 4   PHE A CA  1 
ATOM   2160 C  C   . PHE B 2 8   ? -12.95  -13.241 36.661  1    60.57  ? 4   PHE A C   1 
ATOM   2161 O  O   . PHE B 2 8   ? -12.473 -12.249 37.224  1    64.9   ? 4   PHE A O   1 
ATOM   2162 C  CB  . PHE B 2 8   ? -13.524 -13.032 34.207  1    54.59  ? 4   PHE A CB  1 
ATOM   2163 C  CG  . PHE B 2 8   ? -14.57  -13.182 33.112  1    54.63  ? 4   PHE A CG  1 
ATOM   2164 C  CD1 . PHE B 2 8   ? -14.946 -14.453 32.668  1    52.9   ? 4   PHE A CD1 1 
ATOM   2165 C  CD2 . PHE B 2 8   ? -15.17  -12.06  32.518  1    52.74  ? 4   PHE A CD2 1 
ATOM   2166 C  CE1 . PHE B 2 8   ? -15.912 -14.599 31.665  1    52.38  ? 4   PHE A CE1 1 
ATOM   2167 C  CE2 . PHE B 2 8   ? -16.141 -12.214 31.527  1    51.24  ? 4   PHE A CE2 1 
ATOM   2168 C  CZ  . PHE B 2 8   ? -16.509 -13.48  31.092  1    49     ? 4   PHE A CZ  1 
ATOM   2169 N  N   . GLN B 2 9   ? -12.561 -14.49  36.936  1    58.97  ? 5   GLN A N   1 
ATOM   2170 C  CA  . GLN B 2 9   ? -11.422 -14.84  37.775  1    60.21  ? 5   GLN A CA  1 
ATOM   2171 C  C   . GLN B 2 9   ? -10.446 -15.639 36.913  1    59.34  ? 5   GLN A C   1 
ATOM   2172 O  O   . GLN B 2 9   ? -10.837 -16.656 36.347  1    59.55  ? 5   GLN A O   1 
ATOM   2173 C  CB  . GLN B 2 9   ? -11.908 -15.727 38.925  1    62.4   ? 5   GLN A CB  1 
ATOM   2174 C  CG  . GLN B 2 9   ? -10.835 -16.176 39.915  1    65.11  ? 5   GLN A CG  1 
ATOM   2175 C  CD  . GLN B 2 9   ? -10.318 -15.01  40.726  1    71.66  ? 5   GLN A CD  1 
ATOM   2176 O  OE1 . GLN B 2 9   ? -11.063 -14.379 41.488  1    75.17  ? 5   GLN A OE1 1 
ATOM   2177 N  NE2 . GLN B 2 9   ? -9.057  -14.662 40.52   1    71.6   ? 5   GLN A NE2 1 
ATOM   2178 N  N   . LYS B 2 10  ? -9.199  -15.159 36.778  1    60.06  ? 6   LYS A N   1 
ATOM   2179 C  CA  . LYS B 2 10  ? -8.173  -15.85  36.008  1    58.53  ? 6   LYS A CA  1 
ATOM   2180 C  C   . LYS B 2 10  ? -7.711  -17.046 36.833  1    58.85  ? 6   LYS A C   1 
ATOM   2181 O  O   . LYS B 2 10  ? -7.588  -16.924 38.047  1    59.63  ? 6   LYS A O   1 
ATOM   2182 C  CB  . LYS B 2 10  ? -7.014  -14.926 35.615  1    60.88  ? 6   LYS A CB  1 
ATOM   2183 C  CG  . LYS B 2 10  ? -7.412  -13.795 34.674  1    67.51  ? 6   LYS A CG  1 
ATOM   2184 C  CD  . LYS B 2 10  ? -6.242  -12.953 34.177  1    78.97  ? 6   LYS A CD  1 
ATOM   2185 C  CE  . LYS B 2 10  ? -6.583  -11.88  33.166  1    83.35  ? 6   LYS A CE  1 
ATOM   2186 N  NZ  . LYS B 2 10  ? -6.734  -10.56  33.797  1    85.61  ? 6   LYS A NZ  1 
ATOM   2187 N  N   . VAL B 2 11  ? -7.515  -18.189 36.165  1    58.07  ? 7   VAL A N   1 
ATOM   2188 C  CA  . VAL B 2 11  ? -7.199  -19.439 36.834  1    60.81  ? 7   VAL A CA  1 
ATOM   2189 C  C   . VAL B 2 11  ? -5.734  -19.742 36.544  1    63.21  ? 7   VAL A C   1 
ATOM   2190 O  O   . VAL B 2 11  ? -4.943  -19.842 37.482  1    69.19  ? 7   VAL A O   1 
ATOM   2191 C  CB  . VAL B 2 11  ? -8.163  -20.581 36.433  1    59.22  ? 7   VAL A CB  1 
ATOM   2192 C  CG1 . VAL B 2 11  ? -7.796  -21.947 36.995  1    59.86  ? 7   VAL A CG1 1 
ATOM   2193 C  CG2 . VAL B 2 11  ? -9.601  -20.252 36.799  1    58.04  ? 7   VAL A CG2 1 
ATOM   2194 N  N   . GLU B 2 12  ? -5.384  -19.809 35.252  1    60.62  ? 8   GLU A N   1 
ATOM   2195 C  CA  . GLU B 2 12  ? -4.002  -19.977 34.824  1    63.79  ? 8   GLU A CA  1 
ATOM   2196 C  C   . GLU B 2 12  ? -3.841  -19.528 33.367  1    64.12  ? 8   GLU A C   1 
ATOM   2197 O  O   . GLU B 2 12  ? -4.821  -19.382 32.624  1    61.57  ? 8   GLU A O   1 
ATOM   2198 C  CB  . GLU B 2 12  ? -3.576  -21.441 34.952  1    66.56  ? 8   GLU A CB  1 
ATOM   2199 C  CG  . GLU B 2 12  ? -4.19   -22.321 33.87   1    72.09  ? 8   GLU A CG  1 
ATOM   2200 C  CD  . GLU B 2 12  ? -4.278  -23.813 34.103  1    77.38  ? 8   GLU A CD  1 
ATOM   2201 O  OE1 . GLU B 2 12  ? -4.768  -24.181 35.197  1    79.99  ? 8   GLU A OE1 1 
ATOM   2202 O  OE2 . GLU B 2 12  ? -3.916  -24.582 33.172  1    76.14  ? 8   GLU A OE2 1 
ATOM   2203 N  N   . LYS B 2 13  ? -2.579  -19.346 32.95   1    63.97  ? 9   LYS A N   1 
ATOM   2204 C  CA  . LYS B 2 13  ? -2.255  -19.055 31.565  1    64.87  ? 9   LYS A CA  1 
ATOM   2205 C  C   . LYS B 2 13  ? -2.314  -20.345 30.74   1    63.23  ? 9   LYS A C   1 
ATOM   2206 O  O   . LYS B 2 13  ? -1.853  -21.388 31.188  1    67.27  ? 9   LYS A O   1 
ATOM   2207 C  CB  . LYS B 2 13  ? -0.866  -18.411 31.549  1    69.7   ? 9   LYS A CB  1 
ATOM   2208 C  CG  . LYS B 2 13  ? -0.212  -18.325 30.171  1    77.13  ? 9   LYS A CG  1 
ATOM   2209 C  CD  . LYS B 2 13  ? 1.104   -17.557 30.225  1    85.87  ? 9   LYS A CD  1 
ATOM   2210 C  CE  . LYS B 2 13  ? 1.762   -17.503 28.891  1    91.79  ? 9   LYS A CE  1 
ATOM   2211 N  NZ  . LYS B 2 13  ? 2.595   -16.302 28.775  1    104.49 ? 9   LYS A NZ  1 
ATOM   2212 N  N   . ILE B 2 14  ? -2.863  -20.28  29.523  1    56     ? 10  ILE A N   1 
ATOM   2213 C  CA  . ILE B 2 14  ? -3.034  -21.501 28.764  1    54.93  ? 10  ILE A CA  1 
ATOM   2214 C  C   . ILE B 2 14  ? -2.336  -21.414 27.416  1    57.51  ? 10  ILE A C   1 
ATOM   2215 O  O   . ILE B 2 14  ? -2.141  -22.446 26.764  1    60.81  ? 10  ILE A O   1 
ATOM   2216 C  CB  . ILE B 2 14  ? -4.506  -21.929 28.611  1    54.58  ? 10  ILE A CB  1 
ATOM   2217 C  CG1 . ILE B 2 14  ? -5.436  -20.808 28.124  1    51.55  ? 10  ILE A CG1 1 
ATOM   2218 C  CG2 . ILE B 2 14  ? -4.999  -22.575 29.903  1    60.39  ? 10  ILE A CG2 1 
ATOM   2219 C  CD1 . ILE B 2 14  ? -6.829  -21.278 27.734  1    45.93  ? 10  ILE A CD1 1 
ATOM   2220 N  N   . GLY B 2 15  ? -1.963  -20.196 27.016  1    59.02  ? 11  GLY A N   1 
ATOM   2221 C  CA  . GLY B 2 15  ? -1.497  -19.994 25.653  1    62.81  ? 11  GLY A CA  1 
ATOM   2222 C  C   . GLY B 2 15  ? -0.891  -18.609 25.444  1    68.75  ? 11  GLY A C   1 
ATOM   2223 O  O   . GLY B 2 15  ? -1.038  -17.7   26.264  1    70.63  ? 11  GLY A O   1 
ATOM   2224 N  N   . GLU B 2 16  ? -0.19   -18.485 24.316  1    72.34  ? 12  GLU A N   1 
ATOM   2225 C  CA  . GLU B 2 16  ? 0.352   -17.223 23.866  1    80.05  ? 12  GLU A CA  1 
ATOM   2226 C  C   . GLU B 2 16  ? 0.16    -17.162 22.358  1    96.05  ? 12  GLU A C   1 
ATOM   2227 O  O   . GLU B 2 16  ? 0.83    -17.885 21.621  1    90.61  ? 12  GLU A O   1 
ATOM   2228 C  CB  . GLU B 2 16  ? 1.822   -17.212 24.25   1    83.81  ? 12  GLU A CB  1 
ATOM   2229 C  CG  . GLU B 2 16  ? 2.406   -15.818 24.422  1    93.07  ? 12  GLU A CG  1 
ATOM   2230 C  CD  . GLU B 2 16  ? 3.578   -15.897 25.379  1    112.75 ? 12  GLU A CD  1 
ATOM   2231 O  OE1 . GLU B 2 16  ? 3.923   -17.039 25.773  1    117.43 ? 12  GLU A OE1 1 
ATOM   2232 O  OE2 . GLU B 2 16  ? 4.138   -14.83  25.728  1    125    ? 12  GLU A OE2 1 
ATOM   2233 N  N   . GLY B 2 17  ? -0.845  -16.368 21.954  1    118.24 ? 13  GLY A N   1 
ATOM   2234 C  CA  . GLY B 2 17  ? -1.084  -16.004 20.57   1    120.96 ? 13  GLY A CA  1 
ATOM   2235 C  C   . GLY B 2 17  ? -0.09   -14.93  20.127  1    136.71 ? 13  GLY A C   1 
ATOM   2236 O  O   . GLY B 2 17  ? 0.823   -14.539 20.871  1    115.5  ? 13  GLY A O   1 
ATOM   2237 N  N   . THR B 2 18  ? -0.307  -14.439 18.901  1    136.41 ? 14  THR A N   1 
ATOM   2238 C  CA  . THR B 2 18  ? 0.607   -13.511 18.254  1    121.25 ? 14  THR A CA  1 
ATOM   2239 C  C   . THR B 2 18  ? 0.358   -12.079 18.74   1    116.39 ? 14  THR A C   1 
ATOM   2240 O  O   . THR B 2 18  ? 1.212   -11.214 18.534  1    100.74 ? 14  THR A O   1 
ATOM   2241 C  CB  . THR B 2 18  ? 0.543   -13.683 16.731  1    121.15 ? 14  THR A CB  1 
ATOM   2242 O  OG1 . THR B 2 18  ? 1.356   -12.636 16.212  1    123.38 ? 14  THR A OG1 1 
ATOM   2243 C  CG2 . THR B 2 18  ? -0.866  -13.676 16.152  1    109.15 ? 14  THR A CG2 1 
ATOM   2244 N  N   . TYR B 2 19  ? -0.797  -11.849 19.404  1    118.66 ? 15  TYR A N   1 
ATOM   2245 C  CA  . TYR B 2 19  ? -1.195  -10.532 19.894  1    122.41 ? 15  TYR A CA  1 
ATOM   2246 C  C   . TYR B 2 19  ? -1.394  -10.514 21.407  1    114.31 ? 15  TYR A C   1 
ATOM   2247 O  O   . TYR B 2 19  ? -1.535  -9.445  22.011  1    104    ? 15  TYR A O   1 
ATOM   2248 C  CB  . TYR B 2 19  ? -2.34   -9.89   19.107  1    128.34 ? 15  TYR A CB  1 
ATOM   2249 C  CG  . TYR B 2 19  ? -1.8    -9.175  17.874  1    140.53 ? 15  TYR A CG  1 
ATOM   2250 C  CD1 . TYR B 2 19  ? -1.234  -7.904  17.97   1    136.65 ? 15  TYR A CD1 1 
ATOM   2251 C  CD2 . TYR B 2 19  ? -1.801  -9.796  16.623  1    142.45 ? 15  TYR A CD2 1 
ATOM   2252 C  CE1 . TYR B 2 19  ? -0.71   -7.271  16.852  1    140.13 ? 15  TYR A CE1 1 
ATOM   2253 C  CE2 . TYR B 2 19  ? -1.275  -9.174  15.5    1    133.99 ? 15  TYR A CE2 1 
ATOM   2254 C  CZ  . TYR B 2 19  ? -0.731  -7.905  15.617  1    139.88 ? 15  TYR A CZ  1 
ATOM   2255 O  OH  . TYR B 2 19  ? -0.22   -7.282  14.511  1    146.98 ? 15  TYR A OH  1 
ATOM   2256 N  N   . GLY B 2 20  ? -1.377  -11.699 22.022  1    103.33 ? 16  GLY A N   1 
ATOM   2257 C  CA  . GLY B 2 20  ? -1.139  -11.713 23.455  1    90.56  ? 16  GLY A CA  1 
ATOM   2258 C  C   . GLY B 2 20  ? -1.351  -13.065 24.129  1    79.38  ? 16  GLY A C   1 
ATOM   2259 O  O   . GLY B 2 20  ? -1.291  -14.123 23.513  1    73.54  ? 16  GLY A O   1 
ATOM   2260 N  N   . VAL B 2 21  ? -1.61   -12.963 25.433  1    76.68  ? 17  VAL A N   1 
ATOM   2261 C  CA  . VAL B 2 21  ? -1.744  -14.075 26.354  1    74.8   ? 17  VAL A CA  1 
ATOM   2262 C  C   . VAL B 2 21  ? -3.177  -14.602 26.273  1    68.17  ? 17  VAL A C   1 
ATOM   2263 O  O   . VAL B 2 21  ? -4.097  -13.847 25.991  1    66.67  ? 17  VAL A O   1 
ATOM   2264 C  CB  . VAL B 2 21  ? -1.342  -13.595 27.773  1    76.49  ? 17  VAL A CB  1 
ATOM   2265 C  CG1 . VAL B 2 21  ? -2.178  -12.417 28.286  1    81.94  ? 17  VAL A CG1 1 
ATOM   2266 C  CG2 . VAL B 2 21  ? -1.294  -14.718 28.801  1    72.66  ? 17  VAL A CG2 1 
ATOM   2267 N  N   . VAL B 2 22  ? -3.346  -15.912 26.491  1    60.78  ? 18  VAL A N   1 
ATOM   2268 C  CA  . VAL B 2 22  ? -4.649  -16.51  26.748  1    52.58  ? 18  VAL A CA  1 
ATOM   2269 C  C   . VAL B 2 22  ? -4.668  -17.133 28.145  1    54.76  ? 18  VAL A C   1 
ATOM   2270 O  O   . VAL B 2 22  ? -3.784  -17.896 28.535  1    59.17  ? 18  VAL A O   1 
ATOM   2271 C  CB  . VAL B 2 22  ? -4.991  -17.543 25.671  1    48.47  ? 18  VAL A CB  1 
ATOM   2272 C  CG1 . VAL B 2 22  ? -6.366  -18.158 25.879  1    47.44  ? 18  VAL A CG1 1 
ATOM   2273 C  CG2 . VAL B 2 22  ? -4.897  -16.917 24.29   1    48.8   ? 18  VAL A CG2 1 
ATOM   2274 N  N   . TYR B 2 23  ? -5.692  -16.766 28.908  1    54.86  ? 19  TYR A N   1 
ATOM   2275 C  CA  . TYR B 2 23  ? -5.92   -17.279 30.243  1    57.33  ? 19  TYR A CA  1 
ATOM   2276 C  C   . TYR B 2 23  ? -7.18   -18.154 30.265  1    54.76  ? 19  TYR A C   1 
ATOM   2277 O  O   . TYR B 2 23  ? -8.149  -17.915 29.548  1    51.11  ? 19  TYR A O   1 
ATOM   2278 C  CB  . TYR B 2 23  ? -6.122  -16.051 31.125  1    64.95  ? 19  TYR A CB  1 
ATOM   2279 C  CG  . TYR B 2 23  ? -4.907  -15.262 31.599  1    75.95  ? 19  TYR A CG  1 
ATOM   2280 C  CD1 . TYR B 2 23  ? -4.141  -15.722 32.667  1    81.94  ? 19  TYR A CD1 1 
ATOM   2281 C  CD2 . TYR B 2 23  ? -4.598  -14.01  31.071  1    80.27  ? 19  TYR A CD2 1 
ATOM   2282 C  CE1 . TYR B 2 23  ? -3.072  -14.994 33.163  1    91.09  ? 19  TYR A CE1 1 
ATOM   2283 C  CE2 . TYR B 2 23  ? -3.526  -13.273 31.555  1    91.26  ? 19  TYR A CE2 1 
ATOM   2284 C  CZ  . TYR B 2 23  ? -2.761  -13.765 32.608  1    99.49  ? 19  TYR A CZ  1 
ATOM   2285 O  OH  . TYR B 2 23  ? -1.701  -13.088 33.158  1    109.47 ? 19  TYR A OH  1 
ATOM   2286 N  N   . LYS B 2 24  ? -7.179  -19.199 31.097  1    51.98  ? 20  LYS A N   1 
ATOM   2287 C  CA  . LYS B 2 24  ? -8.429  -19.845 31.457  1    47.64  ? 20  LYS A CA  1 
ATOM   2288 C  C   . LYS B 2 24  ? -9.025  -19.118 32.652  1    49.76  ? 20  LYS A C   1 
ATOM   2289 O  O   . LYS B 2 24  ? -8.324  -18.742 33.599  1    51.46  ? 20  LYS A O   1 
ATOM   2290 C  CB  . LYS B 2 24  ? -8.198  -21.32  31.753  1    47.21  ? 20  LYS A CB  1 
ATOM   2291 C  CG  . LYS B 2 24  ? -9.132  -21.959 32.737  1    48.6   ? 20  LYS A CG  1 
ATOM   2292 C  CD  . LYS B 2 24  ? -8.924  -23.468 32.831  1    50.52  ? 20  LYS A CD  1 
ATOM   2293 C  CE  . LYS B 2 24  ? -9.784  -24.056 33.908  1    54.09  ? 20  LYS A CE  1 
ATOM   2294 N  NZ  . LYS B 2 24  ? -9.671  -25.51  33.977  1    55.19  ? 20  LYS A NZ  1 
ATOM   2295 N  N   . ALA B 2 25  ? -10.34  -18.9   32.586  1    49.1   ? 21  ALA A N   1 
ATOM   2296 C  CA  . ALA B 2 25  ? -11.03  -18.128 33.608  1    49.87  ? 21  ALA A CA  1 
ATOM   2297 C  C   . ALA B 2 25  ? -12.422 -18.715 33.862  1    50.39  ? 21  ALA A C   1 
ATOM   2298 O  O   . ALA B 2 25  ? -12.968 -19.481 33.051  1    50.28  ? 21  ALA A O   1 
ATOM   2299 C  CB  . ALA B 2 25  ? -11.088 -16.676 33.186  1    46.9   ? 21  ALA A CB  1 
ATOM   2300 N  N   . ARG B 2 26  ? -12.96  -18.32  35.008  1    51.71  ? 22  ARG A N   1 
ATOM   2301 C  CA  . ARG B 2 26  ? -14.242 -18.747 35.516  1    55.34  ? 22  ARG A CA  1 
ATOM   2302 C  C   . ARG B 2 26  ? -15.123 -17.505 35.683  1    55.39  ? 22  ARG A C   1 
ATOM   2303 O  O   . ARG B 2 26  ? -14.698 -16.499 36.255  1    52.54  ? 22  ARG A O   1 
ATOM   2304 C  CB  . ARG B 2 26  ? -13.973 -19.499 36.822  1    60.03  ? 22  ARG A CB  1 
ATOM   2305 C  CG  . ARG B 2 26  ? -15.197 -20.078 37.52   1    70.08  ? 22  ARG A CG  1 
ATOM   2306 C  CD  . ARG B 2 26  ? -14.853 -20.907 38.778  1    81.18  ? 22  ARG A CD  1 
ATOM   2307 N  NE  . ARG B 2 26  ? -14.232 -22.199 38.428  1    87.87  ? 22  ARG A NE  1 
ATOM   2308 C  CZ  . ARG B 2 26  ? -14.778 -23.232 37.749  1    83.86  ? 22  ARG A CZ  1 
ATOM   2309 N  NH1 . ARG B 2 26  ? -13.983 -24.203 37.323  1    74.74  ? 22  ARG A NH1 1 
ATOM   2310 N  NH2 . ARG B 2 26  ? -16.08  -23.255 37.444  1    78.1   ? 22  ARG A NH2 1 
ATOM   2311 N  N   . ASN B 2 27  ? -16.332 -17.571 35.103  1    52.65  ? 23  ASN A N   1 
ATOM   2312 C  CA  . ASN B 2 27  ? -17.345 -16.542 35.283  1    49.77  ? 23  ASN A CA  1 
ATOM   2313 C  C   . ASN B 2 27  ? -17.881 -16.669 36.704  1    51.06  ? 23  ASN A C   1 
ATOM   2314 O  O   . ASN B 2 27  ? -18.409 -17.694 37.097  1    52.65  ? 23  ASN A O   1 
ATOM   2315 C  CB  . ASN B 2 27  ? -18.432 -16.644 34.212  1    45.14  ? 23  ASN A CB  1 
ATOM   2316 C  CG  . ASN B 2 27  ? -19.48  -15.565 34.378  1    43.92  ? 23  ASN A CG  1 
ATOM   2317 O  OD1 . ASN B 2 27  ? -19.848 -15.231 35.508  1    44.96  ? 23  ASN A OD1 1 
ATOM   2318 N  ND2 . ASN B 2 27  ? -19.993 -15.027 33.286  1    40.83  ? 23  ASN A ND2 1 
ATOM   2319 N  N   . LYS B 2 28  ? -17.753 -15.621 37.494  1    53.78  ? 24  LYS A N   1 
ATOM   2320 C  CA  . LYS B 2 28  ? -17.95  -15.79  38.92   1    55.1   ? 24  LYS A CA  1 
ATOM   2321 C  C   . LYS B 2 28  ? -19.433 -15.848 39.236  1    53.81  ? 24  LYS A C   1 
ATOM   2322 O  O   . LYS B 2 28  ? -19.81  -16.288 40.315  1    54.65  ? 24  LYS A O   1 
ATOM   2323 C  CB  . LYS B 2 28  ? -17.245 -14.676 39.693  1    60.21  ? 24  LYS A CB  1 
ATOM   2324 C  CG  . LYS B 2 28  ? -15.756 -14.927 39.879  1    65.71  ? 24  LYS A CG  1 
ATOM   2325 C  CD  . LYS B 2 28  ? -15.135 -13.939 40.869  1    72.92  ? 24  LYS A CD  1 
ATOM   2326 C  CE  . LYS B 2 28  ? -15.106 -12.55  40.299  1    71.65  ? 24  LYS A CE  1 
ATOM   2327 N  NZ  . LYS B 2 28  ? -14.582 -11.586 41.265  1    73.77  ? 24  LYS A NZ  1 
ATOM   2328 N  N   . LEU B 2 29  ? -20.264 -15.398 38.293  1    52.91  ? 25  LEU A N   1 
ATOM   2329 C  CA  . LEU B 2 29  ? -21.689 -15.26  38.575  1    53.12  ? 25  LEU A CA  1 
ATOM   2330 C  C   . LEU B 2 29  ? -22.454 -16.487 38.082  1    52.33  ? 25  LEU A C   1 
ATOM   2331 O  O   . LEU B 2 29  ? -23.388 -16.906 38.774  1    53.48  ? 25  LEU A O   1 
ATOM   2332 C  CB  . LEU B 2 29  ? -22.219 -13.962 37.983  1    51.4   ? 25  LEU A CB  1 
ATOM   2333 C  CG  . LEU B 2 29  ? -21.828 -12.713 38.771  1    53.07  ? 25  LEU A CG  1 
ATOM   2334 C  CD1 . LEU B 2 29  ? -22.357 -11.45  38.134  1    52.66  ? 25  LEU A CD1 1 
ATOM   2335 C  CD2 . LEU B 2 29  ? -22.314 -12.835 40.194  1    54.68  ? 25  LEU A CD2 1 
ATOM   2336 N  N   . THR B 2 30  ? -22.035 -17.03  36.914  1    47.22  ? 26  THR A N   1 
ATOM   2337 C  CA  . THR B 2 30  ? -22.731 -18.103 36.222  1    46.34  ? 26  THR A CA  1 
ATOM   2338 C  C   . THR B 2 30  ? -22.003 -19.434 36.388  1    48.46  ? 26  THR A C   1 
ATOM   2339 O  O   . THR B 2 30  ? -22.615 -20.492 36.251  1    49.86  ? 26  THR A O   1 
ATOM   2340 C  CB  . THR B 2 30  ? -22.948 -17.851 34.726  1    42.27  ? 26  THR A CB  1 
ATOM   2341 O  OG1 . THR B 2 30  ? -21.676 -17.996 34.109  1    40.22  ? 26  THR A OG1 1 
ATOM   2342 C  CG2 . THR B 2 30  ? -23.632 -16.536 34.434  1    41.64  ? 26  THR A CG2 1 
ATOM   2343 N  N   . GLY B 2 31  ? -20.682 -19.383 36.572  1    49.07  ? 27  GLY A N   1 
ATOM   2344 C  CA  . GLY B 2 31  ? -19.887 -20.572 36.835  1    48.26  ? 27  GLY A CA  1 
ATOM   2345 C  C   . GLY B 2 31  ? -19.123 -21.015 35.595  1    48.19  ? 27  GLY A C   1 
ATOM   2346 O  O   . GLY B 2 31  ? -18.291 -21.913 35.669  1    51.44  ? 27  GLY A O   1 
ATOM   2347 N  N   . GLU B 2 32  ? -19.397 -20.358 34.468  1    45.48  ? 28  GLU A N   1 
ATOM   2348 C  CA  . GLU B 2 32  ? -18.896 -20.816 33.187  1    44.9   ? 28  GLU A CA  1 
ATOM   2349 C  C   . GLU B 2 32  ? -17.383 -20.628 33.123  1    46.82  ? 28  GLU A C   1 
ATOM   2350 O  O   . GLU B 2 32  ? -16.849 -19.582 33.484  1    49.39  ? 28  GLU A O   1 
ATOM   2351 C  CB  . GLU B 2 32  ? -19.702 -20.199 32.039  1    42.78  ? 28  GLU A CB  1 
ATOM   2352 C  CG  . GLU B 2 32  ? -19.065 -20.378 30.671  1    41.42  ? 28  GLU A CG  1 
ATOM   2353 C  CD  . GLU B 2 32  ? -19.838 -19.94  29.435  1    44.63  ? 28  GLU A CD  1 
ATOM   2354 O  OE1 . GLU B 2 32  ? -20.494 -18.864 29.405  1    42.42  ? 28  GLU A OE1 1 
ATOM   2355 O  OE2 . GLU B 2 32  ? -19.707 -20.711 28.425  1    51.89  ? 28  GLU A OE2 1 
ATOM   2356 N  N   . VAL B 2 33  ? -16.709 -21.68  32.663  1    45.97  ? 29  VAL A N   1 
ATOM   2357 C  CA  . VAL B 2 33  ? -15.298 -21.638 32.346  1    44.12  ? 29  VAL A CA  1 
ATOM   2358 C  C   . VAL B 2 33  ? -15.145 -21.195 30.895  1    44.5   ? 29  VAL A C   1 
ATOM   2359 O  O   . VAL B 2 33  ? -15.788 -21.738 29.991  1    42.68  ? 29  VAL A O   1 
ATOM   2360 C  CB  . VAL B 2 33  ? -14.642 -23.013 32.558  1    43.18  ? 29  VAL A CB  1 
ATOM   2361 C  CG1 . VAL B 2 33  ? -13.151 -22.931 32.29   1    43.78  ? 29  VAL A CG1 1 
ATOM   2362 C  CG2 . VAL B 2 33  ? -14.88  -23.558 33.96   1    44.15  ? 29  VAL A CG2 1 
ATOM   2363 N  N   . VAL B 2 34  ? -14.234 -20.233 30.689  1    45.02  ? 30  VAL A N   1 
ATOM   2364 C  CA  . VAL B 2 34  ? -14.026 -19.573 29.405  1    41.51  ? 30  VAL A CA  1 
ATOM   2365 C  C   . VAL B 2 34  ? -12.523 -19.446 29.197  1    42.03  ? 30  VAL A C   1 
ATOM   2366 O  O   . VAL B 2 34  ? -11.759 -19.624 30.154  1    45.96  ? 30  VAL A O   1 
ATOM   2367 C  CB  . VAL B 2 34  ? -14.694 -18.176 29.408  1    40.17  ? 30  VAL A CB  1 
ATOM   2368 C  CG1 . VAL B 2 34  ? -16.186 -18.266 29.673  1    38.81  ? 30  VAL A CG1 1 
ATOM   2369 C  CG2 . VAL B 2 34  ? -14.058 -17.234 30.432  1    40.65  ? 30  VAL A CG2 1 
ATOM   2370 N  N   . ALA B 2 35  ? -12.124 -19.111 27.966  1    39.16  ? 31  ALA A N   1 
ATOM   2371 C  CA  . ALA B 2 35  ? -10.765 -18.678 27.674  1    39.8   ? 31  ALA A CA  1 
ATOM   2372 C  C   . ALA B 2 35  ? -10.776 -17.197 27.296  1    42.36  ? 31  ALA A C   1 
ATOM   2373 O  O   . ALA B 2 35  ? -11.488 -16.859 26.367  1    44.16  ? 31  ALA A O   1 
ATOM   2374 C  CB  . ALA B 2 35  ? -10.235 -19.464 26.521  1    34.99  ? 31  ALA A CB  1 
ATOM   2375 N  N   . LEU B 2 36  ? -9.979  -16.346 27.97   1    44.15  ? 32  LEU A N   1 
ATOM   2376 C  CA  . LEU B 2 36  ? -9.824  -14.943 27.61   1    45.69  ? 32  LEU A CA  1 
ATOM   2377 C  C   . LEU B 2 36  ? -8.579  -14.757 26.747  1    48.71  ? 32  LEU A C   1 
ATOM   2378 O  O   . LEU B 2 36  ? -7.483  -15.012 27.214  1    57.7   ? 32  LEU A O   1 
ATOM   2379 C  CB  . LEU B 2 36  ? -9.659  -14.13  28.884  1    47.13  ? 32  LEU A CB  1 
ATOM   2380 C  CG  . LEU B 2 36  ? -10.714 -14.308 29.971  1    49.85  ? 32  LEU A CG  1 
ATOM   2381 C  CD1 . LEU B 2 36  ? -10.326 -13.515 31.223  1    49.5   ? 32  LEU A CD1 1 
ATOM   2382 C  CD2 . LEU B 2 36  ? -12.068 -13.86  29.435  1    51.4   ? 32  LEU A CD2 1 
ATOM   2383 N  N   . LYS B 2 37  ? -8.729  -14.256 25.515  1    49.23  ? 33  LYS A N   1 
ATOM   2384 C  CA  . LYS B 2 37  ? -7.614  -13.786 24.704  1    51.96  ? 33  LYS A CA  1 
ATOM   2385 C  C   . LYS B 2 37  ? -7.49   -12.272 24.888  1    56.73  ? 33  LYS A C   1 
ATOM   2386 O  O   . LYS B 2 37  ? -8.354  -11.526 24.45   1    61.66  ? 33  LYS A O   1 
ATOM   2387 C  CB  . LYS B 2 37  ? -7.893  -14.16  23.239  1    53.86  ? 33  LYS A CB  1 
ATOM   2388 C  CG  . LYS B 2 37  ? -6.733  -14.288 22.269  1    57.55  ? 33  LYS A CG  1 
ATOM   2389 C  CD  . LYS B 2 37  ? -7.065  -14.077 20.796  1    60.04  ? 33  LYS A CD  1 
ATOM   2390 C  CE  . LYS B 2 37  ? -6.295  -14.87  19.761  1    61.58  ? 33  LYS A CE  1 
ATOM   2391 N  NZ  . LYS B 2 37  ? -6.96   -16.131 19.379  1    59.86  ? 33  LYS A NZ  1 
ATOM   2392 N  N   . LYS B 2 38  ? -6.427  -11.802 25.547  1    60.28  ? 34  LYS A N   1 
ATOM   2393 C  CA  . LYS B 2 38  ? -6.153  -10.375 25.656  1    62     ? 34  LYS A CA  1 
ATOM   2394 C  C   . LYS B 2 38  ? -5.42   -9.91   24.403  1    66.32  ? 34  LYS A C   1 
ATOM   2395 O  O   . LYS B 2 38  ? -4.469  -10.559 23.975  1    70.68  ? 34  LYS A O   1 
ATOM   2396 C  CB  . LYS B 2 38  ? -5.254  -10.053 26.854  1    68.34  ? 34  LYS A CB  1 
ATOM   2397 C  CG  . LYS B 2 38  ? -5.117  -8.572  27.194  1    76.08  ? 34  LYS A CG  1 
ATOM   2398 C  CD  . LYS B 2 38  ? -3.821  -8.19   27.906  1    86.76  ? 34  LYS A CD  1 
ATOM   2399 C  CE  . LYS B 2 38  ? -3.825  -8.317  29.408  1    91.68  ? 34  LYS A CE  1 
ATOM   2400 N  NZ  . LYS B 2 38  ? -2.536  -8.818  29.896  1    91.97  ? 34  LYS A NZ  1 
ATOM   2401 N  N   . ILE B 2 39  ? -5.883  -8.792  23.825  1    69.09  ? 35  ILE A N   1 
ATOM   2402 C  CA  . ILE B 2 39  ? -5.218  -8.115  22.72   1    67.9   ? 35  ILE A CA  1 
ATOM   2403 C  C   . ILE B 2 39  ? -4.91   -6.679  23.167  1    71.88  ? 35  ILE A C   1 
ATOM   2404 O  O   . ILE B 2 39  ? -5.821  -5.917  23.483  1    72.16  ? 35  ILE A O   1 
ATOM   2405 C  CB  . ILE B 2 39  ? -6.104  -8.211  21.459  1    66.92  ? 35  ILE A CB  1 
ATOM   2406 C  CG1 . ILE B 2 39  ? -6.21   -9.648  20.964  1    65.55  ? 35  ILE A CG1 1 
ATOM   2407 C  CG2 . ILE B 2 39  ? -5.609  -7.286  20.347  1    67.27  ? 35  ILE A CG2 1 
ATOM   2408 C  CD1 . ILE B 2 39  ? -7.262  -9.854  19.896  1    61.85  ? 35  ILE A CD1 1 
ATOM   2409 N  N   . ARG B 2 40  ? -3.63   -6.314  23.228  1    78.37  ? 36  ARG A N   1 
ATOM   2410 C  CA  . ARG B 2 40  ? -3.274  -4.961  23.731  1    89.76  ? 36  ARG A CA  1 
ATOM   2411 C  C   . ARG B 2 40  ? -3.329  -3.953  22.571  1    93.69  ? 36  ARG A C   1 
ATOM   2412 O  O   . ARG B 2 40  ? -2.862  -4.298  21.47   1    91     ? 36  ARG A O   1 
ATOM   2413 C  CB  . ARG B 2 40  ? -1.915  -4.982  24.433  1    96.96  ? 36  ARG A CB  1 
ATOM   2414 C  CG  . ARG B 2 40  ? -1.66   -6.231  25.261  1    104.99 ? 36  ARG A CG  1 
ATOM   2415 C  CD  . ARG B 2 40  ? -0.34   -6.128  26.007  1    107.07 ? 36  ARG A CD  1 
ATOM   2416 N  NE  . ARG B 2 40  ? -0.493  -6.386  27.442  1    109.57 ? 36  ARG A NE  1 
ATOM   2417 C  CZ  . ARG B 2 40  ? -0.778  -5.461  28.347  1    109.08 ? 36  ARG A CZ  1 
ATOM   2418 N  NH1 . ARG B 2 40  ? -0.778  -4.184  28.011  1    106.19 ? 36  ARG A NH1 1 
ATOM   2419 N  NH2 . ARG B 2 40  ? -1.058  -5.817  29.588  1    105.69 ? 36  ARG A NH2 1 
ATOM   2420 N  N   . LEU B 2 41  ? -3.924  -2.784  22.801  1    94.46  ? 37  LEU A N   1 
ATOM   2421 C  CA  . LEU B 2 41  ? -4.073  -1.776  21.723  1    96.82  ? 37  LEU A CA  1 
ATOM   2422 C  C   . LEU B 2 41  ? -3.23   -0.549  22.088  1    117.52 ? 37  LEU A C   1 
ATOM   2423 O  O   . LEU B 2 41  ? -2.929  0.251   21.183  1    126.43 ? 37  LEU A O   1 
ATOM   2424 C  CB  . LEU B 2 41  ? -5.548  -1.433  21.537  1    86.53  ? 37  LEU A CB  1 
ATOM   2425 C  CG  . LEU B 2 41  ? -6.541  -2.588  21.687  1    73.63  ? 37  LEU A CG  1 
ATOM   2426 C  CD1 . LEU B 2 41  ? -7.928  -2.042  21.957  1    68.17  ? 37  LEU A CD1 1 
ATOM   2427 C  CD2 . LEU B 2 41  ? -6.539  -3.439  20.434  1    72.47  ? 37  LEU A CD2 1 
ATOM   2428 N  N   . ASP B 2 42  ? -2.868  -0.41   23.365  1    127.16 ? 38  ASP A N   1 
ATOM   2429 C  CA  . ASP B 2 42  ? -1.982  0.699   23.805  1    133.45 ? 38  ASP A CA  1 
ATOM   2430 C  C   . ASP B 2 42  ? -0.604  0.476   23.185  1    133.59 ? 38  ASP A C   1 
ATOM   2431 O  O   . ASP B 2 42  ? 0.068   1.473   22.859  1    131.22 ? 38  ASP A O   1 
ATOM   2432 C  CB  . ASP B 2 42  ? -1.904  0.759   25.32   1    137.49 ? 38  ASP A CB  1 
ATOM   2433 C  CG  . ASP B 2 42  ? -1.899  -0.59   26.027  1    141.06 ? 38  ASP A CG  1 
ATOM   2434 O  OD1 . ASP B 2 42  ? -1.823  -1.623  25.331  1    142.29 ? 38  ASP A OD1 1 
ATOM   2435 O  OD2 . ASP B 2 42  ? -1.97   -0.6    27.273  1    133.98 ? 38  ASP A OD2 1 
ATOM   2436 N  N   . THR B 2 43  ? -0.211  -0.788  23.023  1    137.25 ? 39  THR A N   1 
ATOM   2437 C  CA  . THR B 2 43  ? 1.075   -1.124  22.388  1    142.25 ? 39  THR A CA  1 
ATOM   2438 C  C   . THR B 2 43  ? 0.907   -1.104  20.894  1    143.41 ? 39  THR A C   1 
ATOM   2439 O  O   . THR B 2 43  ? 1.788   -1.657  20.208  1    137.4  ? 39  THR A O   1 
ATOM   2440 C  CB  . THR B 2 43  ? 1.476   -2.522  22.843  1    145.05 ? 39  THR A CB  1 
ATOM   2441 O  OG1 . THR B 2 43  ? 0.628   -3.397  22.107  1    152.11 ? 39  THR A OG1 1 
ATOM   2442 C  CG2 . THR B 2 43  ? 1.27    -2.732  24.331  1    135.45 ? 39  THR A CG2 1 
ATOM   2443 N  N   . GLU B 2 44  ? -0.184  -0.517  20.395  1    149.57 ? 40  GLU A N   1 
ATOM   2444 C  CA  . GLU B 2 44  ? -0.465  -0.55   18.938  1    139.42 ? 40  GLU A CA  1 
ATOM   2445 C  C   . GLU B 2 44  ? -0.603  0.877   18.394  1    135.84 ? 40  GLU A C   1 
ATOM   2446 O  O   . GLU B 2 44  ? -1.472  1.622   18.891  1    137.37 ? 40  GLU A O   1 
ATOM   2447 C  CB  . GLU B 2 44  ? -1.737  -1.352  18.673  1    131.14 ? 40  GLU A CB  1 
ATOM   2448 C  CG  . GLU B 2 44  ? -1.467  -2.765  18.164  1    126.41 ? 40  GLU A CG  1 
ATOM   2449 C  CD  . GLU B 2 44  ? -1.341  -2.868  16.655  1    128.27 ? 40  GLU A CD  1 
ATOM   2450 O  OE1 . GLU B 2 44  ? -1.636  -1.875  15.958  1    125.99 ? 40  GLU A OE1 1 
ATOM   2451 O  OE2 . GLU B 2 44  ? -0.942  -3.949  16.177  1    123.98 ? 40  GLU A OE2 1 
ATOM   2452 N  N   . THR B 2 45  ? 0.212   1.223   17.398  1    123.56 ? 41  THR A N   1 
ATOM   2453 C  CA  . THR B 2 45  ? 0.151   2.563   16.786  1    117.5  ? 41  THR A CA  1 
ATOM   2454 C  C   . THR B 2 45  ? -0.695  2.497   15.536  1    102.18 ? 41  THR A C   1 
ATOM   2455 O  O   . THR B 2 45  ? -0.95   3.553   14.942  1    103.14 ? 41  THR A O   1 
ATOM   2456 C  CB  . THR B 2 45  ? 1.581   3.023   16.496  1    121.8  ? 41  THR A CB  1 
ATOM   2457 O  OG1 . THR B 2 45  ? 2.163   2.063   15.619  1    123.16 ? 41  THR A OG1 1 
ATOM   2458 C  CG2 . THR B 2 45  ? 2.423   3.128   17.755  1    110.81 ? 41  THR A CG2 1 
ATOM   2459 N  N   . GLU B 2 46  ? -1.104  1.294   15.133  1    87.58  ? 42  GLU A N   1 
ATOM   2460 C  CA  . GLU B 2 46  ? -1.889  1.137   13.884  1    80.28  ? 42  GLU A CA  1 
ATOM   2461 C  C   . GLU B 2 46  ? -3.345  0.866   14.256  1    72.43  ? 42  GLU A C   1 
ATOM   2462 O  O   . GLU B 2 46  ? -4.112  0.454   13.378  1    69.55  ? 42  GLU A O   1 
ATOM   2463 C  CB  . GLU B 2 46  ? -1.286  0.034   13.024  1    78.75  ? 42  GLU A CB  1 
ATOM   2464 C  CG  . GLU B 2 46  ? -0.084  0.506   12.21   1    81.14  ? 42  GLU A CG  1 
ATOM   2465 C  CD  . GLU B 2 46  ? -0.306  1.787   11.428  1    80     ? 42  GLU A CD  1 
ATOM   2466 O  OE1 . GLU B 2 46  ? 0.066   2.86    11.939  1    80.49  ? 42  GLU A OE1 1 
ATOM   2467 O  OE2 . GLU B 2 46  ? -0.844  1.714   10.308  1    72.96  ? 42  GLU A OE2 1 
ATOM   2468 N  N   . GLY B 2 47  ? -3.695  1.11    15.51   1    67.15  ? 43  GLY A N   1 
ATOM   2469 C  CA  . GLY B 2 47  ? -5.067  0.919   15.968  1    60.7   ? 43  GLY A CA  1 
ATOM   2470 C  C   . GLY B 2 47  ? -5.42   -0.556  16.137  1    56.51  ? 43  GLY A C   1 
ATOM   2471 O  O   . GLY B 2 47  ? -4.548  -1.4    16.305  1    58.6   ? 43  GLY A O   1 
ATOM   2472 N  N   . VAL B 2 48  ? -6.709  -0.894  16.061  1    51.51  ? 44  VAL A N   1 
ATOM   2473 C  CA  . VAL B 2 48  ? -7.075  -2.276  16.286  1    46.5   ? 44  VAL A CA  1 
ATOM   2474 C  C   . VAL B 2 48  ? -6.511  -3.126  15.147  1    47.94  ? 44  VAL A C   1 
ATOM   2475 O  O   . VAL B 2 48  ? -6.72   -2.869  13.959  1    48.18  ? 44  VAL A O   1 
ATOM   2476 C  CB  . VAL B 2 48  ? -8.599  -2.399  16.429  1    43.24  ? 44  VAL A CB  1 
ATOM   2477 C  CG1 . VAL B 2 48  ? -9.048  -3.84   16.549  1    39.16  ? 44  VAL A CG1 1 
ATOM   2478 C  CG2 . VAL B 2 48  ? -9.108  -1.568  17.585  1    43.76  ? 44  VAL A CG2 1 
ATOM   2479 N  N   . PRO B 2 49  ? -5.745  -4.188  15.454  1    49.03  ? 45  PRO A N   1 
ATOM   2480 C  CA  . PRO B 2 49  ? -5.083  -4.962  14.402  1    49.04  ? 45  PRO A CA  1 
ATOM   2481 C  C   . PRO B 2 49  ? -6.084  -5.681  13.508  1    49.26  ? 45  PRO A C   1 
ATOM   2482 O  O   . PRO B 2 49  ? -7.15   -6.076  13.96   1    50.26  ? 45  PRO A O   1 
ATOM   2483 C  CB  . PRO B 2 49  ? -4.194  -5.931  15.199  1    47.49  ? 45  PRO A CB  1 
ATOM   2484 C  CG  . PRO B 2 49  ? -4.909  -6.042  16.508  1    46.62  ? 45  PRO A CG  1 
ATOM   2485 C  CD  . PRO B 2 49  ? -5.445  -4.661  16.809  1    48.8   ? 45  PRO A CD  1 
ATOM   2486 N  N   . SER B 2 50  ? -5.712  -5.887  12.24   1    50.67  ? 46  SER A N   1 
ATOM   2487 C  CA  . SER B 2 50  ? -6.614  -6.461  11.256  1    47.86  ? 46  SER A CA  1 
ATOM   2488 C  C   . SER B 2 50  ? -6.918  -7.931  11.534  1    48.07  ? 46  SER A C   1 
ATOM   2489 O  O   . SER B 2 50  ? -8.044  -8.369  11.271  1    50.59  ? 46  SER A O   1 
ATOM   2490 C  CB  . SER B 2 50  ? -6.119  -6.25   9.853   1    49.41  ? 46  SER A CB  1 
ATOM   2491 O  OG  . SER B 2 50  ? -4.94   -6.998  9.608   1    51.75  ? 46  SER A OG  1 
ATOM   2492 N  N   . THR B 2 51  ? -5.939  -8.692  12.058  1    46.77  ? 47  THR A N   1 
ATOM   2493 C  CA  . THR B 2 51  ? -6.201  -10.056 12.512  1    45.71  ? 47  THR A CA  1 
ATOM   2494 C  C   . THR B 2 51  ? -7.39   -10.052 13.471  1    41.96  ? 47  THR A C   1 
ATOM   2495 O  O   . THR B 2 51  ? -8.309  -10.838 13.315  1    37.98  ? 47  THR A O   1 
ATOM   2496 C  CB  . THR B 2 51  ? -4.984  -10.758 13.127  1    49.57  ? 47  THR A CB  1 
ATOM   2497 O  OG1 . THR B 2 51  ? -4.547  -9.981  14.238  1    57.75  ? 47  THR A OG1 1 
ATOM   2498 C  CG2 . THR B 2 51  ? -3.805  -10.831 12.179  1    53.07  ? 47  THR A CG2 1 
ATOM   2499 N  N   . ALA B 2 52  ? -7.382  -9.139  14.443  1    42.25  ? 48  ALA A N   1 
ATOM   2500 C  CA  . ALA B 2 52  ? -8.436  -9.144  15.445  1    45.01  ? 48  ALA A CA  1 
ATOM   2501 C  C   . ALA B 2 52  ? -9.786  -8.732  14.837  1    46.87  ? 48  ALA A C   1 
ATOM   2502 O  O   . ALA B 2 52  ? -10.827 -9.248  15.245  1    47.87  ? 48  ALA A O   1 
ATOM   2503 C  CB  . ALA B 2 52  ? -8.053  -8.277  16.628  1    43.42  ? 48  ALA A CB  1 
ATOM   2504 N  N   . ILE B 2 53  ? -9.756  -7.807  13.868  1    42.92  ? 49  ILE A N   1 
ATOM   2505 C  CA  . ILE B 2 53  ? -10.953 -7.315  13.214  1    41.73  ? 49  ILE A CA  1 
ATOM   2506 C  C   . ILE B 2 53  ? -11.623 -8.423  12.407  1    40.32  ? 49  ILE A C   1 
ATOM   2507 O  O   . ILE B 2 53  ? -12.842 -8.545  12.411  1    39.93  ? 49  ILE A O   1 
ATOM   2508 C  CB  . ILE B 2 53  ? -10.62  -6.093  12.351  1    41.12  ? 49  ILE A CB  1 
ATOM   2509 C  CG1 . ILE B 2 53  ? -10.358 -4.901  13.263  1    40.91  ? 49  ILE A CG1 1 
ATOM   2510 C  CG2 . ILE B 2 53  ? -11.735 -5.855  11.335  1    39.36  ? 49  ILE A CG2 1 
ATOM   2511 C  CD1 . ILE B 2 53  ? -10.112 -3.59   12.554  1    43.01  ? 49  ILE A CD1 1 
ATOM   2512 N  N   . ARG B 2 54  ? -10.815 -9.225  11.723  1    41.4   ? 50  ARG A N   1 
ATOM   2513 C  CA  . ARG B 2 54  ? -11.345 -10.365 10.992  1    41.16  ? 50  ARG A CA  1 
ATOM   2514 C  C   . ARG B 2 54  ? -11.819 -11.455 11.95   1    41.98  ? 50  ARG A C   1 
ATOM   2515 O  O   . ARG B 2 54  ? -12.886 -12.017 11.743  1    44.36  ? 50  ARG A O   1 
ATOM   2516 C  CB  . ARG B 2 54  ? -10.288 -10.934 10.042  1    40.62  ? 50  ARG A CB  1 
ATOM   2517 C  CG  . ARG B 2 54  ? -10.055 -10.031 8.835   1    42.87  ? 50  ARG A CG  1 
ATOM   2518 C  CD  . ARG B 2 54  ? -8.964  -10.593 7.929   1    40.46  ? 50  ARG A CD  1 
ATOM   2519 N  NE  . ARG B 2 54  ? -8.781  -9.805  6.711   1    41.04  ? 50  ARG A NE  1 
ATOM   2520 C  CZ  . ARG B 2 54  ? -7.756  -9.993  5.887   1    41.35  ? 50  ARG A CZ  1 
ATOM   2521 N  NH1 . ARG B 2 54  ? -6.865  -10.952 6.147   1    36.87  ? 50  ARG A NH1 1 
ATOM   2522 N  NH2 . ARG B 2 54  ? -7.655  -9.229  4.805   1    39.64  ? 50  ARG A NH2 1 
ATOM   2523 N  N   . GLU B 2 55  ? -11.02  -11.785 12.972  1    42.56  ? 51  GLU A N   1 
ATOM   2524 C  CA  . GLU B 2 55  ? -11.39  -12.857 13.889  1    41.39  ? 51  GLU A CA  1 
ATOM   2525 C  C   . GLU B 2 55  ? -12.766 -12.566 14.493  1    40.09  ? 51  GLU A C   1 
ATOM   2526 O  O   . GLU B 2 55  ? -13.661 -13.404 14.448  1    40.59  ? 51  GLU A O   1 
ATOM   2527 C  CB  . GLU B 2 55  ? -10.311 -13.128 14.942  1    40.54  ? 51  GLU A CB  1 
ATOM   2528 C  CG  . GLU B 2 55  ? -10.712 -14.276 15.858  1    43.9   ? 51  GLU A CG  1 
ATOM   2529 C  CD  . GLU B 2 55  ? -9.66   -14.96  16.718  1    50.93  ? 51  GLU A CD  1 
ATOM   2530 O  OE1 . GLU B 2 55  ? -8.834  -14.228 17.306  1    45.63  ? 51  GLU A OE1 1 
ATOM   2531 O  OE2 . GLU B 2 55  ? -9.708  -16.237 16.804  1    55.29  ? 51  GLU A OE2 1 
ATOM   2532 N  N   . ILE B 2 56  ? -12.937 -11.355 15.023  1    37.28  ? 52  ILE A N   1 
ATOM   2533 C  CA  . ILE B 2 56  ? -14.15  -10.994 15.724  1    38.94  ? 52  ILE A CA  1 
ATOM   2534 C  C   . ILE B 2 56  ? -15.326 -10.972 14.75   1    41.8   ? 52  ILE A C   1 
ATOM   2535 O  O   . ILE B 2 56  ? -16.317 -11.664 14.986  1    43.83  ? 52  ILE A O   1 
ATOM   2536 C  CB  . ILE B 2 56  ? -14.012 -9.656  16.472  1    40.4   ? 52  ILE A CB  1 
ATOM   2537 C  CG1 . ILE B 2 56  ? -12.908 -9.714  17.528  1    40.19  ? 52  ILE A CG1 1 
ATOM   2538 C  CG2 . ILE B 2 56  ? -15.357 -9.25   17.078  1    40.18  ? 52  ILE A CG2 1 
ATOM   2539 C  CD1 . ILE B 2 56  ? -12.588 -8.383  18.172  1    42.02  ? 52  ILE A CD1 1 
ATOM   2540 N  N   . SER B 2 57  ? -15.219 -10.185 13.673  1    42.32  ? 53  SER A N   1 
ATOM   2541 C  CA  . SER B 2 57  ? -16.326 -10.059 12.727  1    45.5   ? 53  SER A CA  1 
ATOM   2542 C  C   . SER B 2 57  ? -16.767 -11.417 12.151  1    43.26  ? 53  SER A C   1 
ATOM   2543 O  O   . SER B 2 57  ? -17.95  -11.629 11.892  1    48.46  ? 53  SER A O   1 
ATOM   2544 C  CB  . SER B 2 57  ? -16.044 -9.048  11.626  1    42.81  ? 53  SER A CB  1 
ATOM   2545 O  OG  . SER B 2 57  ? -14.999 -9.553  10.815  1    44.73  ? 53  SER A OG  1 
ATOM   2546 N  N   . LEU B 2 58  ? -15.838 -12.339 11.935  1    38.24  ? 54  LEU A N   1 
ATOM   2547 C  CA  . LEU B 2 58  ? -16.226 -13.565 11.267  1    41.74  ? 54  LEU A CA  1 
ATOM   2548 C  C   . LEU B 2 58  ? -16.798 -14.541 12.282  1    46.05  ? 54  LEU A C   1 
ATOM   2549 O  O   . LEU B 2 58  ? -17.721 -15.276 11.946  1    57.14  ? 54  LEU A O   1 
ATOM   2550 C  CB  . LEU B 2 58  ? -15.125 -14.177 10.414  1    37.73  ? 54  LEU A CB  1 
ATOM   2551 C  CG  . LEU B 2 58  ? -14.483 -13.179 9.449   1    38.44  ? 54  LEU A CG  1 
ATOM   2552 C  CD1 . LEU B 2 58  ? -13.207 -13.729 8.839   1    37.26  ? 54  LEU A CD1 1 
ATOM   2553 C  CD2 . LEU B 2 58  ? -15.509 -12.846 8.425   1    35.76  ? 54  LEU A CD2 1 
ATOM   2554 N  N   . LEU B 2 59  ? -16.306 -14.488 13.523  1    45.52  ? 55  LEU A N   1 
ATOM   2555 C  CA  . LEU B 2 59  ? -16.709 -15.476 14.512  1    45.85  ? 55  LEU A CA  1 
ATOM   2556 C  C   . LEU B 2 59  ? -18.092 -15.154 15.072  1    50.97  ? 55  LEU A C   1 
ATOM   2557 O  O   . LEU B 2 59  ? -18.804 -16.059 15.514  1    49.16  ? 55  LEU A O   1 
ATOM   2558 C  CB  . LEU B 2 59  ? -15.681 -15.565 15.632  1    46.68  ? 55  LEU A CB  1 
ATOM   2559 C  CG  . LEU B 2 59  ? -14.55  -16.572 15.431  1    45.27  ? 55  LEU A CG  1 
ATOM   2560 C  CD1 . LEU B 2 59  ? -13.665 -16.545 16.64   1    44.25  ? 55  LEU A CD1 1 
ATOM   2561 C  CD2 . LEU B 2 59  ? -15.074 -17.96  15.215  1    44.27  ? 55  LEU A CD2 1 
ATOM   2562 N  N   . LYS B 2 60  ? -18.439 -13.859 15.073  1    52.68  ? 56  LYS A N   1 
ATOM   2563 C  CA  . LYS B 2 60  ? -19.761 -13.404 15.46   1    55.58  ? 56  LYS A CA  1 
ATOM   2564 C  C   . LYS B 2 60  ? -20.823 -14.23  14.737  1    59.79  ? 56  LYS A C   1 
ATOM   2565 O  O   . LYS B 2 60  ? -21.692 -14.8   15.384  1    62.46  ? 56  LYS A O   1 
ATOM   2566 C  CB  . LYS B 2 60  ? -19.931 -11.902 15.194  1    59.67  ? 56  LYS A CB  1 
ATOM   2567 C  CG  . LYS B 2 60  ? -19.232 -11.015 16.217  1    59.79  ? 56  LYS A CG  1 
ATOM   2568 C  CD  . LYS B 2 60  ? -19.907 -9.653  16.336  1    66.34  ? 56  LYS A CD  1 
ATOM   2569 C  CE  . LYS B 2 60  ? -20.86  -9.606  17.483  1    67.5   ? 56  LYS A CE  1 
ATOM   2570 N  NZ  . LYS B 2 60  ? -21.759 -8.451  17.45   1    70.12  ? 56  LYS A NZ  1 
ATOM   2571 N  N   . GLU B 2 61  ? -20.711 -14.344 13.408  1    61.06  ? 57  GLU A N   1 
ATOM   2572 C  CA  . GLU B 2 61  ? -21.749 -15.003 12.628  1    67.41  ? 57  GLU A CA  1 
ATOM   2573 C  C   . GLU B 2 61  ? -21.506 -16.509 12.375  1    62.39  ? 57  GLU A C   1 
ATOM   2574 O  O   . GLU B 2 61  ? -22.301 -17.156 11.693  1    61.08  ? 57  GLU A O   1 
ATOM   2575 C  CB  . GLU B 2 61  ? -21.997 -14.132 11.397  1    74.54  ? 57  GLU A CB  1 
ATOM   2576 C  CG  . GLU B 2 61  ? -20.735 -13.856 10.581  1    80.97  ? 57  GLU A CG  1 
ATOM   2577 C  CD  . GLU B 2 61  ? -21.031 -12.897 9.431   1    88.43  ? 57  GLU A CD  1 
ATOM   2578 O  OE1 . GLU B 2 61  ? -21.132 -11.687 9.735   1    86.67  ? 57  GLU A OE1 1 
ATOM   2579 O  OE2 . GLU B 2 61  ? -21.186 -13.335 8.255   1    83.11  ? 57  GLU A OE2 1 
ATOM   2580 N  N   . LEU B 2 62  ? -20.397 -17.034 12.906  1    50.79  ? 58  LEU A N   1 
ATOM   2581 C  CA  . LEU B 2 62  ? -20.054 -18.465 12.687  1    48.6   ? 58  LEU A CA  1 
ATOM   2582 C  C   . LEU B 2 62  ? -20.45  -19.281 13.927  1    47.86  ? 58  LEU A C   1 
ATOM   2583 O  O   . LEU B 2 62  ? -19.543 -19.664 14.7    1    48.82  ? 58  LEU A O   1 
ATOM   2584 C  CB  . LEU B 2 62  ? -18.562 -18.601 12.386  1    41.22  ? 58  LEU A CB  1 
ATOM   2585 C  CG  . LEU B 2 62  ? -18.151 -18.413 10.923  1    42.24  ? 58  LEU A CG  1 
ATOM   2586 C  CD1 . LEU B 2 62  ? -16.639 -18.352 10.802  1    40.97  ? 58  LEU A CD1 1 
ATOM   2587 C  CD2 . LEU B 2 62  ? -18.714 -19.514 10.044  1    41.19  ? 58  LEU A CD2 1 
ATOM   2588 N  N   . ASN B 2 63  ? -21.749 -19.537 14.102  1    49.02  ? 59  ASN A N   1 
ATOM   2589 C  CA  . ASN B 2 63  ? -22.219 -20.353 15.257  1    47.31  ? 59  ASN A CA  1 
ATOM   2590 C  C   . ASN B 2 63  ? -22.38  -21.809 14.812  1    43.17  ? 59  ASN A C   1 
ATOM   2591 O  O   . ASN B 2 63  ? -23.319 -22.092 14.037  1    44.38  ? 59  ASN A O   1 
ATOM   2592 C  CB  . ASN B 2 63  ? -23.5   -19.796 15.868  1    53.56  ? 59  ASN A CB  1 
ATOM   2593 C  CG  . ASN B 2 63  ? -23.61  -20.136 17.334  1    80.15  ? 59  ASN A CG  1 
ATOM   2594 O  OD1 . ASN B 2 63  ? -22.61  -20.498 17.965  1    98.46  ? 59  ASN A OD1 1 
ATOM   2595 N  ND2 . ASN B 2 63  ? -24.806 -20.03  17.894  1    84.94  ? 59  ASN A ND2 1 
ATOM   2596 N  N   . HIS B 2 64  ? -21.504 -22.695 15.294  1    38.78  ? 60  HIS A N   1 
ATOM   2597 C  CA  . HIS B 2 64  ? -21.55  -24.128 14.897  1    37.73  ? 60  HIS A CA  1 
ATOM   2598 C  C   . HIS B 2 64  ? -21.004 -24.968 16.057  1    39.01  ? 60  HIS A C   1 
ATOM   2599 O  O   . HIS B 2 64  ? -20.027 -24.525 16.697  1    38.22  ? 60  HIS A O   1 
ATOM   2600 C  CB  . HIS B 2 64  ? -20.758 -24.329 13.6    1    35.25  ? 60  HIS A CB  1 
ATOM   2601 C  CG  . HIS B 2 64  ? -20.874 -25.695 13.019  1    39.23  ? 60  HIS A CG  1 
ATOM   2602 N  ND1 . HIS B 2 64  ? -19.905 -26.659 13.185  1    39.56  ? 60  HIS A ND1 1 
ATOM   2603 C  CD2 . HIS B 2 64  ? -21.84  -26.264 12.288  1    37.03  ? 60  HIS A CD2 1 
ATOM   2604 C  CE1 . HIS B 2 64  ? -20.284 -27.768 12.57   1    35.71  ? 60  HIS A CE1 1 
ATOM   2605 N  NE2 . HIS B 2 64  ? -21.454 -27.549 12.013  1    36.9   ? 60  HIS A NE2 1 
ATOM   2606 N  N   . PRO B 2 65  ? -21.561 -26.163 16.363  1    39.77  ? 61  PRO A N   1 
ATOM   2607 C  CA  . PRO B 2 65  ? -20.994 -26.994 17.426  1    37.9   ? 61  PRO A CA  1 
ATOM   2608 C  C   . PRO B 2 65  ? -19.503 -27.291 17.286  1    37.04  ? 61  PRO A C   1 
ATOM   2609 O  O   . PRO B 2 65  ? -18.866 -27.561 18.297  1    41.23  ? 61  PRO A O   1 
ATOM   2610 C  CB  . PRO B 2 65  ? -21.808 -28.285 17.348  1    37.09  ? 61  PRO A CB  1 
ATOM   2611 C  CG  . PRO B 2 65  ? -23.093 -27.821 16.725  1    40.22  ? 61  PRO A CG  1 
ATOM   2612 C  CD  . PRO B 2 65  ? -22.693 -26.804 15.668  1    38.24  ? 61  PRO A CD  1 
ATOM   2613 N  N   . ASN B 2 66  ? -18.964 -27.256 16.064  1    31.82  ? 62  ASN A N   1 
ATOM   2614 C  CA  . ASN B 2 66  ? -17.587 -27.641 15.797  1    32.74  ? 62  ASN A CA  1 
ATOM   2615 C  C   . ASN B 2 66  ? -16.744 -26.422 15.403  1    35.3   ? 62  ASN A C   1 
ATOM   2616 O  O   . ASN B 2 66  ? -15.692 -26.57  14.773  1    35.85  ? 62  ASN A O   1 
ATOM   2617 C  CB  . ASN B 2 66  ? -17.503 -28.723 14.727  1    31.84  ? 62  ASN A CB  1 
ATOM   2618 C  CG  . ASN B 2 66  ? -18.298 -29.942 15.13   1    37.5   ? 62  ASN A CG  1 
ATOM   2619 O  OD1 . ASN B 2 66  ? -19.394 -30.167 14.602  1    42.56  ? 62  ASN A OD1 1 
ATOM   2620 N  ND2 . ASN B 2 66  ? -17.811 -30.717 16.093  1    34.14  ? 62  ASN A ND2 1 
ATOM   2621 N  N   . ILE B 2 67  ? -17.222 -25.218 15.761  1    33.61  ? 63  ILE A N   1 
ATOM   2622 C  CA  . ILE B 2 67  ? -16.43  -24     15.72   1    34.04  ? 63  ILE A CA  1 
ATOM   2623 C  C   . ILE B 2 67  ? -16.442 -23.404 17.13   1    39.29  ? 63  ILE A C   1 
ATOM   2624 O  O   . ILE B 2 67  ? -17.497 -23.304 17.756  1    46.91  ? 63  ILE A O   1 
ATOM   2625 C  CB  . ILE B 2 67  ? -16.958 -23.029 14.647  1    32.25  ? 63  ILE A CB  1 
ATOM   2626 C  CG1 . ILE B 2 67  ? -16.921 -23.681 13.236  1    32.3   ? 63  ILE A CG1 1 
ATOM   2627 C  CG2 . ILE B 2 67  ? -16.197 -21.696 14.681  1    28.55  ? 63  ILE A CG2 1 
ATOM   2628 C  CD1 . ILE B 2 67  ? -17.694 -22.953 12.135  1    31.07  ? 63  ILE A CD1 1 
ATOM   2629 N  N   . VAL B 2 68  ? -15.262 -23.065 17.659  1    37.76  ? 64  VAL A N   1 
ATOM   2630 C  CA  . VAL B 2 68  ? -15.169 -22.521 19.003  1    40.31  ? 64  VAL A CA  1 
ATOM   2631 C  C   . VAL B 2 68  ? -15.967 -21.227 18.995  1    40.99  ? 64  VAL A C   1 
ATOM   2632 O  O   . VAL B 2 68  ? -15.913 -20.443 18.037  1    37.53  ? 64  VAL A O   1 
ATOM   2633 C  CB  . VAL B 2 68  ? -13.701 -22.327 19.451  1    44.01  ? 64  VAL A CB  1 
ATOM   2634 C  CG1 . VAL B 2 68  ? -13.549 -21.596 20.779  1    39.82  ? 64  VAL A CG1 1 
ATOM   2635 C  CG2 . VAL B 2 68  ? -12.969 -23.666 19.539  1    50.8   ? 64  VAL A CG2 1 
ATOM   2636 N  N   . LYS B 2 69  ? -16.761 -21.068 20.05   1    41.68  ? 65  LYS A N   1 
ATOM   2637 C  CA  . LYS B 2 69  ? -17.712 -19.983 20.081  1    43.55  ? 65  LYS A CA  1 
ATOM   2638 C  C   . LYS B 2 69  ? -17.058 -18.77  20.735  1    45.52  ? 65  LYS A C   1 
ATOM   2639 O  O   . LYS B 2 69  ? -16.423 -18.904 21.785  1    53.08  ? 65  LYS A O   1 
ATOM   2640 C  CB  . LYS B 2 69  ? -18.941 -20.494 20.833  1    46.62  ? 65  LYS A CB  1 
ATOM   2641 C  CG  . LYS B 2 69  ? -20.083 -19.478 20.802  1    52.68  ? 65  LYS A CG  1 
ATOM   2642 C  CD  . LYS B 2 69  ? -21.377 -20.038 21.374  1    62     ? 65  LYS A CD  1 
ATOM   2643 C  CE  . LYS B 2 69  ? -22.479 -19.018 21.319  1    62.39  ? 65  LYS A CE  1 
ATOM   2644 N  NZ  . LYS B 2 69  ? -22.484 -18.478 19.957  1    56.34  ? 65  LYS A NZ  1 
ATOM   2645 N  N   . LEU B 2 70  ? -17.209 -17.601 20.095  1    41.46  ? 66  LEU A N   1 
ATOM   2646 C  CA  . LEU B 2 70  ? -16.902 -16.309 20.698  1    39.23  ? 66  LEU A CA  1 
ATOM   2647 C  C   . LEU B 2 70  ? -18.114 -15.879 21.519  1    39.82  ? 66  LEU A C   1 
ATOM   2648 O  O   . LEU B 2 70  ? -19.178 -15.644 20.951  1    40.68  ? 66  LEU A O   1 
ATOM   2649 C  CB  . LEU B 2 70  ? -16.624 -15.325 19.557  1    38.39  ? 66  LEU A CB  1 
ATOM   2650 C  CG  . LEU B 2 70  ? -16.22  -13.895 19.935  1    39.55  ? 66  LEU A CG  1 
ATOM   2651 C  CD1 . LEU B 2 70  ? -15.073 -13.888 20.892  1    39.24  ? 66  LEU A CD1 1 
ATOM   2652 C  CD2 . LEU B 2 70  ? -15.767 -13.124 18.706  1    39.24  ? 66  LEU A CD2 1 
ATOM   2653 N  N   . LEU B 2 71  ? -17.959 -15.794 22.846  1    39.31  ? 67  LEU A N   1 
ATOM   2654 C  CA  . LEU B 2 71  ? -19.075 -15.513 23.735  1    36.53  ? 67  LEU A CA  1 
ATOM   2655 C  C   . LEU B 2 71  ? -19.262 -14.015 23.875  1    38.83  ? 67  LEU A C   1 
ATOM   2656 O  O   . LEU B 2 71  ? -20.382 -13.558 24.074  1    42.89  ? 67  LEU A O   1 
ATOM   2657 C  CB  . LEU B 2 71  ? -18.88  -16.169 25.093  1    35.28  ? 67  LEU A CB  1 
ATOM   2658 C  CG  . LEU B 2 71  ? -18.607 -17.68  25.083  1    35.42  ? 67  LEU A CG  1 
ATOM   2659 C  CD1 . LEU B 2 71  ? -18.405 -18.246 26.498  1    34.68  ? 67  LEU A CD1 1 
ATOM   2660 C  CD2 . LEU B 2 71  ? -19.721 -18.437 24.38   1    33.54  ? 67  LEU A CD2 1 
ATOM   2661 N  N   . ASP B 2 72  ? -18.172 -13.247 23.784  1    39.6   ? 68  ASP A N   1 
ATOM   2662 C  CA  . ASP B 2 72  ? -18.258 -11.826 24.092  1    41.94  ? 68  ASP A CA  1 
ATOM   2663 C  C   . ASP B 2 72  ? -16.942 -11.141 23.721  1    42.4   ? 68  ASP A C   1 
ATOM   2664 O  O   . ASP B 2 72  ? -15.93  -11.819 23.485  1    39.96  ? 68  ASP A O   1 
ATOM   2665 C  CB  . ASP B 2 72  ? -18.568 -11.603 25.57   1    45.42  ? 68  ASP A CB  1 
ATOM   2666 C  CG  . ASP B 2 72  ? -19.247 -10.288 25.928  1    51.43  ? 68  ASP A CG  1 
ATOM   2667 O  OD1 . ASP B 2 72  ? -19.473 -9.452  25.019  1    54.88  ? 68  ASP A OD1 1 
ATOM   2668 O  OD2 . ASP B 2 72  ? -19.605 -10.135 27.107  1    56.3   ? 68  ASP A OD2 1 
ATOM   2669 N  N   . VAL B 2 73  ? -16.991 -9.793  23.699  1    41.37  ? 69  VAL A N   1 
ATOM   2670 C  CA  . VAL B 2 73  ? -15.867 -8.917  23.424  1    41.57  ? 69  VAL A CA  1 
ATOM   2671 C  C   . VAL B 2 73  ? -15.924 -7.739  24.391  1    45.79  ? 69  VAL A C   1 
ATOM   2672 O  O   . VAL B 2 73  ? -16.867 -6.951  24.34   1    47.8   ? 69  VAL A O   1 
ATOM   2673 C  CB  . VAL B 2 73  ? -15.941 -8.413  21.974  1    40.13  ? 69  VAL A CB  1 
ATOM   2674 C  CG1 . VAL B 2 73  ? -14.884 -7.346  21.725  1    40.62  ? 69  VAL A CG1 1 
ATOM   2675 C  CG2 . VAL B 2 73  ? -15.864 -9.54   20.939  1    36.62  ? 69  VAL A CG2 1 
ATOM   2676 N  N   . ILE B 2 74  ? -14.882 -7.6    25.217  1    49.43  ? 70  ILE A N   1 
ATOM   2677 C  CA  . ILE B 2 74  ? -14.797 -6.443  26.158  1    54.26  ? 70  ILE A CA  1 
ATOM   2678 C  C   . ILE B 2 74  ? -13.722 -5.481  25.627  1    58.43  ? 70  ILE A C   1 
ATOM   2679 O  O   . ILE B 2 74  ? -12.534 -5.683  25.964  1    57.22  ? 70  ILE A O   1 
ATOM   2680 C  CB  . ILE B 2 74  ? -14.477 -6.923  27.586  1    55.85  ? 70  ILE A CB  1 
ATOM   2681 C  CG1 . ILE B 2 74  ? -15.608 -7.776  28.164  1    57.73  ? 70  ILE A CG1 1 
ATOM   2682 C  CG2 . ILE B 2 74  ? -14.137 -5.743  28.495  1    56.42  ? 70  ILE A CG2 1 
ATOM   2683 C  CD1 . ILE B 2 74  ? -15.358 -9.271  28.095  1    56.46  ? 70  ILE A CD1 1 
ATOM   2684 N  N   . HIS B 2 75  ? -14.166 -4.449  24.918  1    66.73  ? 71  HIS A N   1 
ATOM   2685 C  CA  . HIS B 2 75  ? -13.244 -3.442  24.338  1    80.98  ? 71  HIS A CA  1 
ATOM   2686 C  C   . HIS B 2 75  ? -13.116 -2.254  25.28   1    82.05  ? 71  HIS A C   1 
ATOM   2687 O  O   . HIS B 2 75  ? -14.054 -1.453  25.385  1    90.86  ? 71  HIS A O   1 
ATOM   2688 C  CB  . HIS B 2 75  ? -13.704 -2.886  22.982  1    87.17  ? 71  HIS A CB  1 
ATOM   2689 C  CG  . HIS B 2 75  ? -15.015 -2.176  22.878  1    102.83 ? 71  HIS A CG  1 
ATOM   2690 N  ND1 . HIS B 2 75  ? -16.168 -2.928  22.902  1    111.35 ? 71  HIS A ND1 1 
ATOM   2691 C  CD2 . HIS B 2 75  ? -15.413 -0.904  22.756  1    116.27 ? 71  HIS A CD2 1 
ATOM   2692 C  CE1 . HIS B 2 75  ? -17.218 -2.128  22.8    1    122.69 ? 71  HIS A CE1 1 
ATOM   2693 N  NE2 . HIS B 2 75  ? -16.781 -0.893  22.711  1    126.81 ? 71  HIS A NE2 1 
ATOM   2694 N  N   . THR B 2 76  ? -11.968 -2.147  25.933  1    88.98  ? 72  THR A N   1 
ATOM   2695 C  CA  . THR B 2 76  ? -11.715 -0.985  26.795  1    94.16  ? 72  THR A CA  1 
ATOM   2696 C  C   . THR B 2 76  ? -10.947 0.016   25.969  1    92.5   ? 72  THR A C   1 
ATOM   2697 O  O   . THR B 2 76  ? -10.988 -0.073  24.73   1    77.73  ? 72  THR A O   1 
ATOM   2698 C  CB  . THR B 2 76  ? -10.956 -1.437  28.041  1    86.56  ? 72  THR A CB  1 
ATOM   2699 O  OG1 . THR B 2 76  ? -9.597  -1.592  27.651  1    83.14  ? 72  THR A OG1 1 
ATOM   2700 C  CG2 . THR B 2 76  ? -11.477 -2.754  28.587  1    77.17  ? 72  THR A CG2 1 
ATOM   2701 N  N   . GLU B 2 77  ? -10.246 0.93    26.626  1    100.23 ? 73  GLU A N   1 
ATOM   2702 C  CA  . GLU B 2 77  ? -9.535  1.993   25.882  1    101.48 ? 73  GLU A CA  1 
ATOM   2703 C  C   . GLU B 2 77  ? -8.169  1.473   25.443  1    96.83  ? 73  GLU A C   1 
ATOM   2704 O  O   . GLU B 2 77  ? -7.728  1.838   24.336  1    92.97  ? 73  GLU A O   1 
ATOM   2705 C  CB  . GLU B 2 77  ? -9.386  3.214   26.784  1    114.61 ? 73  GLU A CB  1 
ATOM   2706 C  CG  . GLU B 2 77  ? -10.649 4.065   26.844  1    119.38 ? 73  GLU A CG  1 
ATOM   2707 C  CD  . GLU B 2 77  ? -10.481 5.318   26.013  1    129.97 ? 73  GLU A CD  1 
ATOM   2708 O  OE1 . GLU B 2 77  ? -11.164 5.443   24.976  1    133.15 ? 73  GLU A OE1 1 
ATOM   2709 O  OE2 . GLU B 2 77  ? -9.651  6.165   26.402  1    130.93 ? 73  GLU A OE2 1 
ATOM   2710 N  N   . ASN B 2 78  ? -7.533  0.655   26.277  1    90.72  ? 74  ASN A N   1 
ATOM   2711 C  CA  . ASN B 2 78  ? -6.156  0.205   25.945  1    89.49  ? 74  ASN A CA  1 
ATOM   2712 C  C   . ASN B 2 78  ? -6.142  -1.307  25.745  1    82.92  ? 74  ASN A C   1 
ATOM   2713 O  O   . ASN B 2 78  ? -5.08   -1.84   25.381  1    87.36  ? 74  ASN A O   1 
ATOM   2714 C  CB  . ASN B 2 78  ? -5.179  0.648   27.024  1    91.9   ? 74  ASN A CB  1 
ATOM   2715 C  CG  . ASN B 2 78  ? -5.162  2.147   27.191  1    91.97  ? 74  ASN A CG  1 
ATOM   2716 O  OD1 . ASN B 2 78  ? -5.115  2.882   26.2    1    90.76  ? 74  ASN A OD1 1 
ATOM   2717 N  ND2 . ASN B 2 78  ? -5.205  2.617   28.428  1    89.35  ? 74  ASN A ND2 1 
ATOM   2718 N  N   . LYS B 2 79  ? -7.285  -1.96   25.945  1    79.89  ? 75  LYS A N   1 
ATOM   2719 C  CA  . LYS B 2 79  ? -7.303  -3.438  25.865  1    76.74  ? 75  LYS A CA  1 
ATOM   2720 C  C   . LYS B 2 79  ? -8.582  -3.969  25.205  1    66.77  ? 75  LYS A C   1 
ATOM   2721 O  O   . LYS B 2 79  ? -9.625  -3.303  25.293  1    64.98  ? 75  LYS A O   1 
ATOM   2722 C  CB  . LYS B 2 79  ? -7.149  -3.994  27.282  1    83.13  ? 75  LYS A CB  1 
ATOM   2723 C  CG  . LYS B 2 79  ? -5.801  -3.731  27.923  1    91.68  ? 75  LYS A CG  1 
ATOM   2724 C  CD  . LYS B 2 79  ? -5.725  -4.289  29.338  1    101.91 ? 75  LYS A CD  1 
ATOM   2725 C  CE  . LYS B 2 79  ? -4.389  -4.049  29.958  1    102.3  ? 75  LYS A CE  1 
ATOM   2726 N  NZ  . LYS B 2 79  ? -4.337  -4.569  31.325  1    102.04 ? 75  LYS A NZ  1 
ATOM   2727 N  N   . LEU B 2 80  ? -8.475  -5.128  24.56   1    60.13  ? 76  LEU A N   1 
ATOM   2728 C  CA  . LEU B 2 80  ? -9.64   -5.79   23.936  1    57.23  ? 76  LEU A CA  1 
ATOM   2729 C  C   . LEU B 2 80  ? -9.601  -7.254  24.379  1    57.65  ? 76  LEU A C   1 
ATOM   2730 O  O   . LEU B 2 80  ? -8.563  -7.898  24.171  1    55.9   ? 76  LEU A O   1 
ATOM   2731 C  CB  . LEU B 2 80  ? -9.521  -5.632  22.425  1    55.39  ? 76  LEU A CB  1 
ATOM   2732 C  CG  . LEU B 2 80  ? -10.566 -6.344  21.567  1    54.77  ? 76  LEU A CG  1 
ATOM   2733 C  CD1 . LEU B 2 80  ? -11.838 -5.536  21.578  1    56.63  ? 76  LEU A CD1 1 
ATOM   2734 C  CD2 . LEU B 2 80  ? -10.017 -6.429  20.158  1    55.45  ? 76  LEU A CD2 1 
ATOM   2735 N  N   . TYR B 2 81  ? -10.669 -7.734  25.013  1    56.27  ? 77  TYR A N   1 
ATOM   2736 C  CA  . TYR B 2 81  ? -10.712 -9.115  25.49   1    52.47  ? 77  TYR A CA  1 
ATOM   2737 C  C   . TYR B 2 81  ? -11.732 -9.929  24.698  1    50.28  ? 77  TYR A C   1 
ATOM   2738 O  O   . TYR B 2 81  ? -12.895 -9.54   24.587  1    51.59  ? 77  TYR A O   1 
ATOM   2739 C  CB  . TYR B 2 81  ? -11.077 -9.134  26.975  1    56.9   ? 77  TYR A CB  1 
ATOM   2740 C  CG  . TYR B 2 81  ? -9.958  -8.758  27.942  1    65.43  ? 77  TYR A CG  1 
ATOM   2741 C  CD1 . TYR B 2 81  ? -9.04   -9.703  28.404  1    69.29  ? 77  TYR A CD1 1 
ATOM   2742 C  CD2 . TYR B 2 81  ? -9.827  -7.461  28.422  1    67.51  ? 77  TYR A CD2 1 
ATOM   2743 C  CE1 . TYR B 2 81  ? -8.014  -9.359  29.277  1    74.17  ? 77  TYR A CE1 1 
ATOM   2744 C  CE2 . TYR B 2 81  ? -8.82   -7.11   29.311  1    74.74  ? 77  TYR A CE2 1 
ATOM   2745 C  CZ  . TYR B 2 81  ? -7.912  -8.06   29.749  1    78.61  ? 77  TYR A CZ  1 
ATOM   2746 O  OH  . TYR B 2 81  ? -6.926  -7.701  30.634  1    86.8   ? 77  TYR A OH  1 
ATOM   2747 N  N   . LEU B 2 82  ? -11.288 -11.047 24.119  1    44.87  ? 78  LEU A N   1 
ATOM   2748 C  CA  . LEU B 2 82  ? -12.2   -11.971 23.472  1    43.9   ? 78  LEU A CA  1 
ATOM   2749 C  C   . LEU B 2 82  ? -12.527 -13.085 24.464  1    46.09  ? 78  LEU A C   1 
ATOM   2750 O  O   . LEU B 2 82  ? -11.62  -13.708 24.984  1    50.63  ? 78  LEU A O   1 
ATOM   2751 C  CB  . LEU B 2 82  ? -11.605 -12.564 22.197  1    40.34  ? 78  LEU A CB  1 
ATOM   2752 C  CG  . LEU B 2 82  ? -10.959 -11.6   21.204  1    40.18  ? 78  LEU A CG  1 
ATOM   2753 C  CD1 . LEU B 2 82  ? -11.151 -12.178 19.817  1    38.43  ? 78  LEU A CD1 1 
ATOM   2754 C  CD2 . LEU B 2 82  ? -11.46  -10.202 21.274  1    43.73  ? 78  LEU A CD2 1 
ATOM   2755 N  N   . VAL B 2 83  ? -13.81  -13.341 24.745  1    45.73  ? 79  VAL A N   1 
ATOM   2756 C  CA  . VAL B 2 83  ? -14.2   -14.433 25.633  1    43.38  ? 79  VAL A CA  1 
ATOM   2757 C  C   . VAL B 2 83  ? -14.653 -15.596 24.758  1    41.98  ? 79  VAL A C   1 
ATOM   2758 O  O   . VAL B 2 83  ? -15.58  -15.444 23.977  1    42.56  ? 79  VAL A O   1 
ATOM   2759 C  CB  . VAL B 2 83  ? -15.357 -13.985 26.546  1    43.39  ? 79  VAL A CB  1 
ATOM   2760 C  CG1 . VAL B 2 83  ? -15.624 -14.969 27.683  1    42.03  ? 79  VAL A CG1 1 
ATOM   2761 C  CG2 . VAL B 2 83  ? -15.158 -12.564 27.057  1    41.69  ? 79  VAL A CG2 1 
ATOM   2762 N  N   . PHE B 2 84  ? -13.991 -16.749 24.873  1    43.03  ? 80  PHE A N   1 
ATOM   2763 C  CA  . PHE B 2 84  ? -14.307 -17.915 24.058  1    40.69  ? 80  PHE A CA  1 
ATOM   2764 C  C   . PHE B 2 84  ? -14.739 -19.041 24.982  1    41.75  ? 80  PHE A C   1 
ATOM   2765 O  O   . PHE B 2 84  ? -14.278 -19.108 26.115  1    44.56  ? 80  PHE A O   1 
ATOM   2766 C  CB  . PHE B 2 84  ? -13.107 -18.496 23.31   1    38.79  ? 80  PHE A CB  1 
ATOM   2767 C  CG  . PHE B 2 84  ? -12.5   -17.652 22.198  1    39.02  ? 80  PHE A CG  1 
ATOM   2768 C  CD1 . PHE B 2 84  ? -11.556 -16.675 22.474  1    38.48  ? 80  PHE A CD1 1 
ATOM   2769 C  CD2 . PHE B 2 84  ? -12.99  -17.742 20.895  1    36.97  ? 80  PHE A CD2 1 
ATOM   2770 C  CE1 . PHE B 2 84  ? -11.087 -15.87  21.443  1    40.55  ? 80  PHE A CE1 1 
ATOM   2771 C  CE2 . PHE B 2 84  ? -12.468 -16.957 19.876  1    35.59  ? 80  PHE A CE2 1 
ATOM   2772 C  CZ  . PHE B 2 84  ? -11.516 -16.03  20.146  1    35.19  ? 80  PHE A CZ  1 
ATOM   2773 N  N   . GLU B 2 85  ? -15.561 -19.957 24.471  1    41.95  ? 81  GLU A N   1 
ATOM   2774 C  CA  . GLU B 2 85  ? -15.778 -21.202 25.188  1    43.11  ? 81  GLU A CA  1 
ATOM   2775 C  C   . GLU B 2 85  ? -14.428 -21.878 25.432  1    42.61  ? 81  GLU A C   1 
ATOM   2776 O  O   . GLU B 2 85  ? -13.543 -21.79  24.596  1    41.47  ? 81  GLU A O   1 
ATOM   2777 C  CB  . GLU B 2 85  ? -16.797 -22.1   24.482  1    40.93  ? 81  GLU A CB  1 
ATOM   2778 C  CG  . GLU B 2 85  ? -16.272 -22.703 23.197  1    40.52  ? 81  GLU A CG  1 
ATOM   2779 C  CD  . GLU B 2 85  ? -17.083 -23.881 22.684  1    44.6   ? 81  GLU A CD  1 
ATOM   2780 O  OE1 . GLU B 2 85  ? -17.416 -24.809 23.462  1    44.32  ? 81  GLU A OE1 1 
ATOM   2781 O  OE2 . GLU B 2 85  ? -17.35  -23.871 21.458  1    45.42  ? 81  GLU A OE2 1 
ATOM   2782 N  N   . PHE B 2 86  ? -14.294 -22.529 26.597  1    42.86  ? 82  PHE A N   1 
ATOM   2783 C  CA  . PHE B 2 86  ? -13.07  -23.196 26.998  1    40.16  ? 82  PHE A CA  1 
ATOM   2784 C  C   . PHE B 2 86  ? -13.096 -24.638 26.532  1    40.61  ? 82  PHE A C   1 
ATOM   2785 O  O   . PHE B 2 86  ? -14.03  -25.366 26.847  1    42.38  ? 82  PHE A O   1 
ATOM   2786 C  CB  . PHE B 2 86  ? -12.928 -23.237 28.523  1    41.51  ? 82  PHE A CB  1 
ATOM   2787 C  CG  . PHE B 2 86  ? -11.669 -23.956 28.978  1    41.16  ? 82  PHE A CG  1 
ATOM   2788 C  CD1 . PHE B 2 86  ? -10.407 -23.419 28.7    1    40.4   ? 82  PHE A CD1 1 
ATOM   2789 C  CD2 . PHE B 2 86  ? -11.754 -25.194 29.618  1    40.33  ? 82  PHE A CD2 1 
ATOM   2790 C  CE1 . PHE B 2 86  ? -9.252  -24.117 29.063  1    41.73  ? 82  PHE A CE1 1 
ATOM   2791 C  CE2 . PHE B 2 86  ? -10.604 -25.87  30.019  1    41.16  ? 82  PHE A CE2 1 
ATOM   2792 C  CZ  . PHE B 2 86  ? -9.351  -25.344 29.725  1    42     ? 82  PHE A CZ  1 
ATOM   2793 N  N   . LEU B 2 87  ? -12.002 -25.04  25.888  1    42.08  ? 83  LEU A N   1 
ATOM   2794 C  CA  . LEU B 2 87  ? -11.785 -26.454 25.513  1    40.97  ? 83  LEU A CA  1 
ATOM   2795 C  C   . LEU B 2 87  ? -10.409 -26.77  26.106  1    43.19  ? 83  LEU A C   1 
ATOM   2796 O  O   . LEU B 2 87  ? -9.514  -25.926 25.961  1    41.18  ? 83  LEU A O   1 
ATOM   2797 C  CB  . LEU B 2 87  ? -11.868 -26.677 24.007  1    39.36  ? 83  LEU A CB  1 
ATOM   2798 C  CG  . LEU B 2 87  ? -13.276 -26.689 23.409  1    40.3   ? 83  LEU A CG  1 
ATOM   2799 C  CD1 . LEU B 2 87  ? -13.582 -25.354 22.762  1    35.35  ? 83  LEU A CD1 1 
ATOM   2800 C  CD2 . LEU B 2 87  ? -13.42  -27.815 22.409  1    37.49  ? 83  LEU A CD2 1 
ATOM   2801 N  N   . HIS B 2 88  ? -10.241 -27.928 26.74   1    46.99  ? 84  HIS A N   1 
ATOM   2802 C  CA  . HIS B 2 88  ? -8.991  -28.219 27.501  1    49.66  ? 84  HIS A CA  1 
ATOM   2803 C  C   . HIS B 2 88  ? -7.758  -28.578 26.663  1    50.39  ? 84  HIS A C   1 
ATOM   2804 O  O   . HIS B 2 88  ? -6.661  -28.397 27.209  1    51.02  ? 84  HIS A O   1 
ATOM   2805 C  CB  . HIS B 2 88  ? -9.261  -29.29  28.564  1    50.25  ? 84  HIS A CB  1 
ATOM   2806 C  CG  . HIS B 2 88  ? -9.202  -30.704 28.103  1    59.23  ? 84  HIS A CG  1 
ATOM   2807 N  ND1 . HIS B 2 88  ? -8.333  -31.616 28.659  1    69.72  ? 84  HIS A ND1 1 
ATOM   2808 C  CD2 . HIS B 2 88  ? -9.903  -31.372 27.186  1    61.55  ? 84  HIS A CD2 1 
ATOM   2809 C  CE1 . HIS B 2 88  ? -8.504  -32.79  28.074  1    67.18  ? 84  HIS A CE1 1 
ATOM   2810 N  NE2 . HIS B 2 88  ? -9.453  -32.664 27.177  1    65.74  ? 84  HIS A NE2 1 
ATOM   2811 N  N   . GLN B 2 89  ? -7.895  -29.055 25.427  1    46.97  ? 85  GLN A N   1 
ATOM   2812 C  CA  . GLN B 2 89  ? -6.668  -29.488 24.713  1    46.45  ? 85  GLN A CA  1 
ATOM   2813 C  C   . GLN B 2 89  ? -6.707  -29.242 23.204  1    43.91  ? 85  GLN A C   1 
ATOM   2814 O  O   . GLN B 2 89  ? -7.787  -28.974 22.677  1    43.38  ? 85  GLN A O   1 
ATOM   2815 C  CB  . GLN B 2 89  ? -6.448  -30.984 24.922  1    50.36  ? 85  GLN A CB  1 
ATOM   2816 C  CG  . GLN B 2 89  ? -4.983  -31.389 25.013  1    55.09  ? 85  GLN A CG  1 
ATOM   2817 C  CD  . GLN B 2 89  ? -4.807  -32.869 25.258  1    63     ? 85  GLN A CD  1 
ATOM   2818 O  OE1 . GLN B 2 89  ? -3.711  -33.347 25.559  1    69.18  ? 85  GLN A OE1 1 
ATOM   2819 N  NE2 . GLN B 2 89  ? -5.899  -33.607 25.135  1    72.84  ? 85  GLN A NE2 1 
ATOM   2820 N  N   . ASP B 2 90  ? -5.544  -29.32  22.562  1    40.14  ? 86  ASP A N   1 
ATOM   2821 C  CA  . ASP B 2 90  ? -5.459  -29.218 21.086  1    41.11  ? 86  ASP A CA  1 
ATOM   2822 C  C   . ASP B 2 90  ? -5.125  -30.613 20.563  1    42.56  ? 86  ASP A C   1 
ATOM   2823 O  O   . ASP B 2 90  ? -4.742  -31.462 21.376  1    46.01  ? 86  ASP A O   1 
ATOM   2824 C  CB  . ASP B 2 90  ? -4.439  -28.187 20.64   1    43.51  ? 86  ASP A CB  1 
ATOM   2825 C  CG  . ASP B 2 90  ? -3.024  -28.369 21.159  1    47.32  ? 86  ASP A CG  1 
ATOM   2826 O  OD1 . ASP B 2 90  ? -2.77   -27.972 22.309  1    55.59  ? 86  ASP A OD1 1 
ATOM   2827 O  OD2 . ASP B 2 90  ? -2.191  -28.886 20.399  1    51.51  ? 86  ASP A OD2 1 
ATOM   2828 N  N   . LEU B 2 91  ? -5.267  -30.838 19.262  1    38.59  ? 87  LEU A N   1 
ATOM   2829 C  CA  . LEU B 2 91  ? -5.046  -32.196 18.713  1    41.07  ? 87  LEU A CA  1 
ATOM   2830 C  C   . LEU B 2 91  ? -3.537  -32.484 18.663  1    44.44  ? 87  LEU A C   1 
ATOM   2831 O  O   . LEU B 2 91  ? -3.172  -33.659 18.774  1    45.72  ? 87  LEU A O   1 
ATOM   2832 C  CB  . LEU B 2 91  ? -5.729  -32.332 17.355  1    38.28  ? 87  LEU A CB  1 
ATOM   2833 C  CG  . LEU B 2 91  ? -5.543  -33.654 16.61   1    39.04  ? 87  LEU A CG  1 
ATOM   2834 C  CD1 . LEU B 2 91  ? -6.335  -34.756 17.278  1    41.73  ? 87  LEU A CD1 1 
ATOM   2835 C  CD2 . LEU B 2 91  ? -5.994  -33.46  15.18   1    35.74  ? 87  LEU A CD2 1 
ATOM   2836 N  N   . LYS B 2 92  ? -2.702  -31.45  18.578  1    42.35  ? 88  LYS A N   1 
ATOM   2837 C  CA  . LYS B 2 92  ? -1.27   -31.72  18.548  1    44.38  ? 88  LYS A CA  1 
ATOM   2838 C  C   . LYS B 2 92  ? -0.827  -32.279 19.899  1    45.53  ? 88  LYS A C   1 
ATOM   2839 O  O   . LYS B 2 92  ? -0.132  -33.295 19.956  1    47.32  ? 88  LYS A O   1 
ATOM   2840 C  CB  . LYS B 2 92  ? -0.48   -30.457 18.202  1    45.49  ? 88  LYS A CB  1 
ATOM   2841 C  CG  . LYS B 2 92  ? 1.029   -30.597 18.161  1    51.56  ? 88  LYS A CG  1 
ATOM   2842 C  CD  . LYS B 2 92  ? 1.631   -31.556 17.137  1    63.7   ? 88  LYS A CD  1 
ATOM   2843 C  CE  . LYS B 2 92  ? 3.118   -31.498 17.065  1    68.52  ? 88  LYS A CE  1 
ATOM   2844 N  NZ  . LYS B 2 92  ? 3.615   -32.584 16.228  1    69.55  ? 88  LYS A NZ  1 
ATOM   2845 N  N   . LYS B 2 93  ? -1.296  -31.645 20.983  1    46.9   ? 89  LYS A N   1 
ATOM   2846 C  CA  . LYS B 2 93  ? -0.949  -32.022 22.344  1    49.31  ? 89  LYS A CA  1 
ATOM   2847 C  C   . LYS B 2 93  ? -1.495  -33.421 22.666  1    52.58  ? 89  LYS A C   1 
ATOM   2848 O  O   . LYS B 2 93  ? -0.807  -34.236 23.295  1    55.94  ? 89  LYS A O   1 
ATOM   2849 C  CB  . LYS B 2 93  ? -1.399  -30.925 23.312  1    52.51  ? 89  LYS A CB  1 
ATOM   2850 C  CG  . LYS B 2 93  ? -0.646  -29.605 23.166  1    68.39  ? 89  LYS A CG  1 
ATOM   2851 C  CD  . LYS B 2 93  ? -1.084  -28.473 24.103  1    78.61  ? 89  LYS A CD  1 
ATOM   2852 C  CE  . LYS B 2 93  ? -0.327  -27.159 23.985  1    75.89  ? 89  LYS A CE  1 
ATOM   2853 N  NZ  . LYS B 2 93  ? -0.831  -26.13  24.902  1    69.16  ? 89  LYS A NZ  1 
ATOM   2854 N  N   . PHE B 2 94  ? -2.717  -33.728 22.199  1    47.69  ? 90  PHE A N   1 
ATOM   2855 C  CA  . PHE B 2 94  ? -3.299  -35.046 22.423  1    47.9   ? 90  PHE A CA  1 
ATOM   2856 C  C   . PHE B 2 94  ? -2.505  -36.134 21.691  1    49.18  ? 90  PHE A C   1 
ATOM   2857 O  O   . PHE B 2 94  ? -2.252  -37.201 22.251  1    51.3   ? 90  PHE A O   1 
ATOM   2858 C  CB  . PHE B 2 94  ? -4.767  -35.033 21.996  1    44.6   ? 90  PHE A CB  1 
ATOM   2859 C  CG  . PHE B 2 94  ? -5.489  -36.371 22      1    41.01  ? 90  PHE A CG  1 
ATOM   2860 C  CD1 . PHE B 2 94  ? -5.726  -37.044 23.188  1    43.04  ? 90  PHE A CD1 1 
ATOM   2861 C  CD2 . PHE B 2 94  ? -5.964  -36.921 20.82   1    40.39  ? 90  PHE A CD2 1 
ATOM   2862 C  CE1 . PHE B 2 94  ? -6.385  -38.261 23.205  1    42.74  ? 90  PHE A CE1 1 
ATOM   2863 C  CE2 . PHE B 2 94  ? -6.642  -38.13  20.842  1    42.67  ? 90  PHE A CE2 1 
ATOM   2864 C  CZ  . PHE B 2 94  ? -6.847  -38.795 22.031  1    43.08  ? 90  PHE A CZ  1 
ATOM   2865 N  N   . MET B 2 95  ? -2.142  -35.885 20.426  1    46.77  ? 91  MET A N   1 
ATOM   2866 C  CA  . MET B 2 95  ? -1.296  -36.797 19.67   1    49.11  ? 91  MET A CA  1 
ATOM   2867 C  C   . MET B 2 95  ? 0.057   -37.054 20.355  1    56.69  ? 91  MET A C   1 
ATOM   2868 O  O   . MET B 2 95  ? 0.513   -38.195 20.409  1    63.68  ? 91  MET A O   1 
ATOM   2869 C  CB  . MET B 2 95  ? -1.123  -36.29  18.24   1    46.88  ? 91  MET A CB  1 
ATOM   2870 C  CG  . MET B 2 95  ? -2.269  -36.717 17.34   1    46.62  ? 91  MET A CG  1 
ATOM   2871 S  SD  . MET B 2 95  ? -2.166  -36.1   15.645  1    55.11  ? 91  MET A SD  1 
ATOM   2872 C  CE  . MET B 2 95  ? -1.841  -34.341 15.792  1    47.07  ? 91  MET A CE  1 
ATOM   2873 N  N   . ASP B 2 96  ? 0.703   -36.022 20.921  1    56.94  ? 92  ASP A N   1 
ATOM   2874 C  CA  . ASP B 2 96  ? 2.049   -36.206 21.444  1    56.4   ? 92  ASP A CA  1 
ATOM   2875 C  C   . ASP B 2 96  ? 2.023   -36.922 22.78   1    58.18  ? 92  ASP A C   1 
ATOM   2876 O  O   . ASP B 2 96  ? 2.914   -37.713 23.063  1    65.6   ? 92  ASP A O   1 
ATOM   2877 C  CB  . ASP B 2 96  ? 2.776   -34.895 21.704  1    55.33  ? 92  ASP A CB  1 
ATOM   2878 C  CG  . ASP B 2 96  ? 3.012   -34.023 20.482  1    55.35  ? 92  ASP A CG  1 
ATOM   2879 O  OD1 . ASP B 2 96  ? 3.048   -34.562 19.32   1    52.11  ? 92  ASP A OD1 1 
ATOM   2880 O  OD2 . ASP B 2 96  ? 3.087   -32.798 20.707  1    58.74  ? 92  ASP A OD2 1 
ATOM   2881 N  N   . ALA B 2 97  ? 1.029   -36.642 23.612  1    61.13  ? 93  ALA A N   1 
ATOM   2882 C  CA  . ALA B 2 97  ? 1.084   -37.174 24.993  1    63.25  ? 93  ALA A CA  1 
ATOM   2883 C  C   . ALA B 2 97  ? 0.217   -38.406 25.241  1    67.89  ? 93  ALA A C   1 
ATOM   2884 O  O   . ALA B 2 97  ? 0.597   -39.194 26.116  1    75.52  ? 93  ALA A O   1 
ATOM   2885 C  CB  . ALA B 2 97  ? 0.709   -36.071 25.939  1    60.44  ? 93  ALA A CB  1 
ATOM   2886 N  N   . SER B 2 98  ? -0.903  -38.563 24.552  1    65.53  ? 94  SER A N   1 
ATOM   2887 C  CA  . SER B 2 98  ? -1.794  -39.697 24.907  1    69.84  ? 94  SER A CA  1 
ATOM   2888 C  C   . SER B 2 98  ? -1.849  -40.71  23.762  1    65.77  ? 94  SER A C   1 
ATOM   2889 O  O   . SER B 2 98  ? -2.12   -41.897 24.022  1    64.57  ? 94  SER A O   1 
ATOM   2890 C  CB  . SER B 2 98  ? -3.17   -39.216 25.3    1    66.71  ? 94  SER A CB  1 
ATOM   2891 O  OG  . SER B 2 98  ? -3.093  -38.144 26.227  1    70.46  ? 94  SER A OG  1 
ATOM   2892 N  N   . ALA B 2 99  ? -1.6    -40.244 22.547  1    57.79  ? 95  ALA A N   1 
ATOM   2893 C  CA  . ALA B 2 99  ? -1.644  -41.148 21.386  1    56.28  ? 95  ALA A CA  1 
ATOM   2894 C  C   . ALA B 2 99  ? -0.218  -41.619 21.134  1    62.85  ? 95  ALA A C   1 
ATOM   2895 O  O   . ALA B 2 99  ? 0.485   -41.052 20.301  1    67.08  ? 95  ALA A O   1 
ATOM   2896 C  CB  . ALA B 2 99  ? -2.254  -40.428 20.23   1    47.79  ? 95  ALA A CB  1 
ATOM   2897 N  N   . LEU B 2 100 ? 0.228   -42.585 21.926  1    73.8   ? 96  LEU A N   1 
ATOM   2898 C  CA  . LEU B 2 100 ? 1.612   -43.09  21.806  1    73.96  ? 96  LEU A CA  1 
ATOM   2899 C  C   . LEU B 2 100 ? 1.564   -44.377 20.99   1    75.89  ? 96  LEU A C   1 
ATOM   2900 O  O   . LEU B 2 100 ? 2.51    -44.627 20.231  1    84.16  ? 96  LEU A O   1 
ATOM   2901 C  CB  . LEU B 2 100 ? 2.137   -43.345 23.212  1    77.32  ? 96  LEU A CB  1 
ATOM   2902 C  CG  . LEU B 2 100 ? 2.304   -42.137 24.136  1    78.98  ? 96  LEU A CG  1 
ATOM   2903 C  CD1 . LEU B 2 100 ? 2.692   -42.49  25.555  1    75.3   ? 96  LEU A CD1 1 
ATOM   2904 C  CD2 . LEU B 2 100 ? 3.272   -41.153 23.518  1    76.4   ? 96  LEU A CD2 1 
ATOM   2905 N  N   . THR B 2 101 ? 0.502   -45.159 21.158  1    73.7   ? 97  THR A N   1 
ATOM   2906 C  CA  . THR B 2 101 ? 0.33    -46.378 20.351  1    71     ? 97  THR A CA  1 
ATOM   2907 C  C   . THR B 2 101 ? -0.768  -46.141 19.343  1    71.5   ? 97  THR A C   1 
ATOM   2908 O  O   . THR B 2 101 ? -1.225  -47.126 18.735  1    69.74  ? 97  THR A O   1 
ATOM   2909 C  CB  . THR B 2 101 ? 0.038   -47.57  21.257  1    72.54  ? 97  THR A CB  1 
ATOM   2910 O  OG1 . THR B 2 101 ? -1.16   -47.234 21.947  1    75.53  ? 97  THR A OG1 1 
ATOM   2911 C  CG2 . THR B 2 101 ? 1.161   -47.829 22.243  1    70.32  ? 97  THR A CG2 1 
ATOM   2912 N  N   . GLY B 2 102 ? -1.235  -44.899 19.198  1    63.52  ? 98  GLY A N   1 
ATOM   2913 C  CA  . GLY B 2 102 ? -2.178  -44.632 18.125  1    57.93  ? 98  GLY A CA  1 
ATOM   2914 C  C   . GLY B 2 102 ? -3.445  -43.955 18.638  1    58.52  ? 98  GLY A C   1 
ATOM   2915 O  O   . GLY B 2 102 ? -3.686  -43.942 19.847  1    56.49  ? 98  GLY A O   1 
ATOM   2916 N  N   . ILE B 2 103 ? -4.204  -43.365 17.697  1    56.16  ? 99  ILE A N   1 
ATOM   2917 C  CA  . ILE B 2 103 ? -5.576  -42.936 17.921  1    52.13  ? 99  ILE A CA  1 
ATOM   2918 C  C   . ILE B 2 103 ? -6.478  -44.019 17.348  1    50.31  ? 99  ILE A C   1 
ATOM   2919 O  O   . ILE B 2 103 ? -6.38   -44.321 16.17   1    49.27  ? 99  ILE A O   1 
ATOM   2920 C  CB  . ILE B 2 103 ? -5.853  -41.587 17.244  1    50.77  ? 99  ILE A CB  1 
ATOM   2921 C  CG1 . ILE B 2 103 ? -4.851  -40.529 17.701  1    51.24  ? 99  ILE A CG1 1 
ATOM   2922 C  CG2 . ILE B 2 103 ? -7.31   -41.161 17.461  1    48.22  ? 99  ILE A CG2 1 
ATOM   2923 C  CD1 . ILE B 2 103 ? -5.286  -39.099 17.434  1    50.13  ? 99  ILE A CD1 1 
ATOM   2924 N  N   . PRO B 2 104 ? -7.423  -44.595 18.128  1    51.7   ? 100 PRO A N   1 
ATOM   2925 C  CA  . PRO B 2 104 ? -8.287  -45.664 17.609  1    50.15  ? 100 PRO A CA  1 
ATOM   2926 C  C   . PRO B 2 104 ? -9.132  -45.124 16.463  1    48.69  ? 100 PRO A C   1 
ATOM   2927 O  O   . PRO B 2 104 ? -9.461  -43.938 16.452  1    47.13  ? 100 PRO A O   1 
ATOM   2928 C  CB  . PRO B 2 104 ? -9.146  -46.066 18.801  1    54.82  ? 100 PRO A CB  1 
ATOM   2929 C  CG  . PRO B 2 104 ? -8.428  -45.464 19.994  1    55.66  ? 100 PRO A CG  1 
ATOM   2930 C  CD  . PRO B 2 104 ? -7.767  -44.185 19.5    1    49.26  ? 100 PRO A CD  1 
ATOM   2931 N  N   . LEU B 2 105 ? -9.458  -46     15.503  1    51.75  ? 101 LEU A N   1 
ATOM   2932 C  CA  . LEU B 2 105 ? -10.151 -45.617 14.277  1    51.97  ? 101 LEU A CA  1 
ATOM   2933 C  C   . LEU B 2 105 ? -11.473 -44.916 14.617  1    53.09  ? 101 LEU A C   1 
ATOM   2934 O  O   . LEU B 2 105 ? -11.769 -43.838 14.091  1    53.71  ? 101 LEU A O   1 
ATOM   2935 C  CB  . LEU B 2 105 ? -10.406 -46.85  13.418  1    51.67  ? 101 LEU A CB  1 
ATOM   2936 C  CG  . LEU B 2 105 ? -11.192 -46.643 12.117  1    55.65  ? 101 LEU A CG  1 
ATOM   2937 C  CD1 . LEU B 2 105 ? -10.416 -45.73  11.184  1    58.57  ? 101 LEU A CD1 1 
ATOM   2938 C  CD2 . LEU B 2 105 ? -11.647 -47.902 11.387  1    52.29  ? 101 LEU A CD2 1 
ATOM   2939 N  N   . PRO B 2 106 ? -12.323 -45.503 15.491  1    49.79  ? 102 PRO A N   1 
ATOM   2940 C  CA  . PRO B 2 106 ? -13.518 -44.805 15.969  1    49.12  ? 102 PRO A CA  1 
ATOM   2941 C  C   . PRO B 2 106 ? -13.341 -43.311 16.224  1    49.22  ? 102 PRO A C   1 
ATOM   2942 O  O   . PRO B 2 106 ? -14.173 -42.512 15.791  1    51.89  ? 102 PRO A O   1 
ATOM   2943 C  CB  . PRO B 2 106 ? -13.879 -45.59  17.234  1    50     ? 102 PRO A CB  1 
ATOM   2944 C  CG  . PRO B 2 106 ? -13.462 -47.012 16.883  1    50.08  ? 102 PRO A CG  1 
ATOM   2945 C  CD  . PRO B 2 106 ? -12.22  -46.883 15.998  1    48.42  ? 102 PRO A CD  1 
ATOM   2946 N  N   . LEU B 2 107 ? -12.258 -42.93  16.914  1    47.82  ? 103 LEU A N   1 
ATOM   2947 C  CA  . LEU B 2 107 ? -12.083 -41.551 17.354  1    43.64  ? 103 LEU A CA  1 
ATOM   2948 C  C   . LEU B 2 107 ? -11.506 -40.726 16.201  1    43.32  ? 103 LEU A C   1 
ATOM   2949 O  O   . LEU B 2 107 ? -11.69  -39.506 16.135  1    43.38  ? 103 LEU A O   1 
ATOM   2950 C  CB  . LEU B 2 107 ? -11.187 -41.581 18.586  1    44.6   ? 103 LEU A CB  1 
ATOM   2951 C  CG  . LEU B 2 107 ? -11.013 -40.285 19.392  1    50.27  ? 103 LEU A CG  1 
ATOM   2952 C  CD1 . LEU B 2 107 ? -12.334 -39.633 19.859  1    50.06  ? 103 LEU A CD1 1 
ATOM   2953 C  CD2 . LEU B 2 107 ? -10.099 -40.564 20.603  1    48.49  ? 103 LEU A CD2 1 
ATOM   2954 N  N   . ILE B 2 108 ? -10.849 -41.393 15.241  1    43.22  ? 104 ILE A N   1 
ATOM   2955 C  CA  . ILE B 2 108 ? -10.307 -40.679 14.094  1    42.04  ? 104 ILE A CA  1 
ATOM   2956 C  C   . ILE B 2 108 ? -11.452 -40.268 13.165  1    43.91  ? 104 ILE A C   1 
ATOM   2957 O  O   . ILE B 2 108 ? -11.47  -39.136 12.661  1    42.82  ? 104 ILE A O   1 
ATOM   2958 C  CB  . ILE B 2 108 ? -9.245  -41.517 13.369  1    40.41  ? 104 ILE A CB  1 
ATOM   2959 C  CG1 . ILE B 2 108 ? -7.959  -41.653 14.192  1    41.1   ? 104 ILE A CG1 1 
ATOM   2960 C  CG2 . ILE B 2 108 ? -8.958  -40.893 12.005  1    41.61  ? 104 ILE A CG2 1 
ATOM   2961 C  CD1 . ILE B 2 108 ? -6.858  -42.491 13.529  1    36.52  ? 104 ILE A CD1 1 
ATOM   2962 N  N   . LYS B 2 109 ? -12.381 -41.218 12.944  1    41.34  ? 105 LYS A N   1 
ATOM   2963 C  CA  . LYS B 2 109 ? -13.568 -41.028 12.124  1    41.52  ? 105 LYS A CA  1 
ATOM   2964 C  C   . LYS B 2 109 ? -14.422 -39.9   12.694  1    40.14  ? 105 LYS A C   1 
ATOM   2965 O  O   . LYS B 2 109 ? -14.842 -38.987 11.97   1    35.88  ? 105 LYS A O   1 
ATOM   2966 C  CB  . LYS B 2 109 ? -14.456 -42.278 12.078  1    41.59  ? 105 LYS A CB  1 
ATOM   2967 C  CG  . LYS B 2 109 ? -13.903 -43.397 11.221  1    43.24  ? 105 LYS A CG  1 
ATOM   2968 C  CD  . LYS B 2 109 ? -14.799 -44.617 11.11   1    44.86  ? 105 LYS A CD  1 
ATOM   2969 C  CE  . LYS B 2 109 ? -14.118 -45.619 10.204  1    48.14  ? 105 LYS A CE  1 
ATOM   2970 N  NZ  . LYS B 2 109 ? -14.901 -46.859 10.045  1    52.09  ? 105 LYS A NZ  1 
ATOM   2971 N  N   . SER B 2 110 ? -14.694 -40.022 13.998  1    42.08  ? 106 SER A N   1 
ATOM   2972 C  CA  . SER B 2 110 ? -15.462 -39.05  14.754  1    42.6   ? 106 SER A CA  1 
ATOM   2973 C  C   . SER B 2 110 ? -14.859 -37.656 14.603  1    42.1   ? 106 SER A C   1 
ATOM   2974 O  O   . SER B 2 110 ? -15.587 -36.738 14.223  1    41.93  ? 106 SER A O   1 
ATOM   2975 C  CB  . SER B 2 110 ? -15.643 -39.445 16.194  1    43.7   ? 106 SER A CB  1 
ATOM   2976 O  OG  . SER B 2 110 ? -16.219 -38.357 16.904  1    45.24  ? 106 SER A OG  1 
ATOM   2977 N  N   . TYR B 2 111 ? -13.545 -37.513 14.855  1    41.19  ? 107 TYR A N   1 
ATOM   2978 C  CA  . TYR B 2 111 ? -12.905 -36.201 14.81   1    42.52  ? 107 TYR A CA  1 
ATOM   2979 C  C   . TYR B 2 111 ? -12.963 -35.636 13.386  1    41.87  ? 107 TYR A C   1 
ATOM   2980 O  O   . TYR B 2 111 ? -13.288 -34.461 13.202  1    39.89  ? 107 TYR A O   1 
ATOM   2981 C  CB  . TYR B 2 111 ? -11.452 -36.194 15.312  1    45.89  ? 107 TYR A CB  1 
ATOM   2982 C  CG  . TYR B 2 111 ? -11.181 -36.233 16.814  1    50.09  ? 107 TYR A CG  1 
ATOM   2983 C  CD1 . TYR B 2 111 ? -12.202 -36.087 17.755  1    51.7   ? 107 TYR A CD1 1 
ATOM   2984 C  CD2 . TYR B 2 111 ? -9.893  -36.455 17.299  1    50.78  ? 107 TYR A CD2 1 
ATOM   2985 C  CE1 . TYR B 2 111 ? -11.939 -36.126 19.119  1    53.77  ? 107 TYR A CE1 1 
ATOM   2986 C  CE2 . TYR B 2 111 ? -9.619  -36.491 18.66   1    49.82  ? 107 TYR A CE2 1 
ATOM   2987 C  CZ  . TYR B 2 111 ? -10.646 -36.322 19.567  1    52.46  ? 107 TYR A CZ  1 
ATOM   2988 O  OH  . TYR B 2 111 ? -10.406 -36.346 20.9    1    64.63  ? 107 TYR A OH  1 
ATOM   2989 N  N   . LEU B 2 112 ? -12.643 -36.475 12.379  1    37.52  ? 108 LEU A N   1 
ATOM   2990 C  CA  . LEU B 2 112 ? -12.593 -35.99  11.009  1    36.49  ? 108 LEU A CA  1 
ATOM   2991 C  C   . LEU B 2 112 ? -13.988 -35.583 10.519  1    38.9   ? 108 LEU A C   1 
ATOM   2992 O  O   . LEU B 2 112 ? -14.141 -34.615 9.753   1    38.28  ? 108 LEU A O   1 
ATOM   2993 C  CB  . LEU B 2 112 ? -11.958 -37.026 10.087  1    34.13  ? 108 LEU A CB  1 
ATOM   2994 C  CG  . LEU B 2 112 ? -11.855 -36.605 8.619   1    31.37  ? 108 LEU A CG  1 
ATOM   2995 C  CD1 . LEU B 2 112 ? -11.057 -35.334 8.481   1    29.53  ? 108 LEU A CD1 1 
ATOM   2996 C  CD2 . LEU B 2 112 ? -11.206 -37.693 7.806   1    30.64  ? 108 LEU A CD2 1 
ATOM   2997 N  N   . PHE B 2 113 ? -15.001 -36.366 10.929  1    36.66  ? 109 PHE A N   1 
ATOM   2998 C  CA  . PHE B 2 113 ? -16.37  -36.052 10.58   1    36.49  ? 109 PHE A CA  1 
ATOM   2999 C  C   . PHE B 2 113 ? -16.766 -34.711 11.183  1    38.36  ? 109 PHE A C   1 
ATOM   3000 O  O   . PHE B 2 113 ? -17.399 -33.897 10.522  1    40.32  ? 109 PHE A O   1 
ATOM   3001 C  CB  . PHE B 2 113 ? -17.282 -37.12  11.146  1    37.5   ? 109 PHE A CB  1 
ATOM   3002 C  CG  . PHE B 2 113 ? -18.672 -37.146 10.531  1    38.83  ? 109 PHE A CG  1 
ATOM   3003 C  CD1 . PHE B 2 113 ? -18.835 -37.404 9.172   1    36.52  ? 109 PHE A CD1 1 
ATOM   3004 C  CD2 . PHE B 2 113 ? -19.795 -37.025 11.341  1    37.92  ? 109 PHE A CD2 1 
ATOM   3005 C  CE1 . PHE B 2 113 ? -20.1   -37.493 8.633   1    36.91  ? 109 PHE A CE1 1 
ATOM   3006 C  CE2 . PHE B 2 113 ? -21.058 -37.128 10.804  1    40.24  ? 109 PHE A CE2 1 
ATOM   3007 C  CZ  . PHE B 2 113 ? -21.208 -37.37  9.45    1    41.98  ? 109 PHE A CZ  1 
ATOM   3008 N  N   . GLN B 2 114 ? -16.344 -34.458 12.423  1    39.1   ? 110 GLN A N   1 
ATOM   3009 C  CA  . GLN B 2 114 ? -16.708 -33.214 13.067  1    36.66  ? 110 GLN A CA  1 
ATOM   3010 C  C   . GLN B 2 114 ? -16.001 -32.052 12.374  1    37.42  ? 110 GLN A C   1 
ATOM   3011 O  O   . GLN B 2 114 ? -16.619 -31     12.178  1    35.91  ? 110 GLN A O   1 
ATOM   3012 C  CB  . GLN B 2 114 ? -16.359 -33.277 14.546  1    35.19  ? 110 GLN A CB  1 
ATOM   3013 C  CG  . GLN B 2 114 ? -17.313 -34.121 15.373  1    36.59  ? 110 GLN A CG  1 
ATOM   3014 C  CD  . GLN B 2 114 ? -16.907 -34.072 16.827  1    40.75  ? 110 GLN A CD  1 
ATOM   3015 O  OE1 . GLN B 2 114 ? -17.121 -33.065 17.516  1    45.6   ? 110 GLN A OE1 1 
ATOM   3016 N  NE2 . GLN B 2 114 ? -16.283 -35.141 17.302  1    38.75  ? 110 GLN A NE2 1 
ATOM   3017 N  N   . LEU B 2 115 ? -14.718 -32.252 12.019  1    35.08  ? 111 LEU A N   1 
ATOM   3018 C  CA  . LEU B 2 115 ? -13.935 -31.206 11.385  1    35.03  ? 111 LEU A CA  1 
ATOM   3019 C  C   . LEU B 2 115 ? -14.577 -30.801 10.058  1    38.65  ? 111 LEU A C   1 
ATOM   3020 O  O   . LEU B 2 115 ? -14.657 -29.616 9.746   1    37.34  ? 111 LEU A O   1 
ATOM   3021 C  CB  . LEU B 2 115 ? -12.501 -31.684 11.199  1    34.35  ? 111 LEU A CB  1 
ATOM   3022 C  CG  . LEU B 2 115 ? -11.703 -31.73  12.505  1    37.63  ? 111 LEU A CG  1 
ATOM   3023 C  CD1 . LEU B 2 115 ? -10.381 -32.442 12.347  1    37.22  ? 111 LEU A CD1 1 
ATOM   3024 C  CD2 . LEU B 2 115 ? -11.49  -30.32  13.077  1    35.69  ? 111 LEU A CD2 1 
ATOM   3025 N  N   . LEU B 2 116 ? -15.05  -31.794 9.287   1    37.36  ? 112 LEU A N   1 
ATOM   3026 C  CA  . LEU B 2 116 ? -15.688 -31.549 8.002   1    36.22  ? 112 LEU A CA  1 
ATOM   3027 C  C   . LEU B 2 116 ? -17.012 -30.8   8.172   1    41.44  ? 112 LEU A C   1 
ATOM   3028 O  O   . LEU B 2 116 ? -17.357 -29.965 7.329   1    44.95  ? 112 LEU A O   1 
ATOM   3029 C  CB  . LEU B 2 116 ? -15.855 -32.875 7.263   1    34.12  ? 112 LEU A CB  1 
ATOM   3030 C  CG  . LEU B 2 116 ? -14.564 -33.435 6.647   1    31.52  ? 112 LEU A CG  1 
ATOM   3031 C  CD1 . LEU B 2 116 ? -14.707 -34.9   6.342   1    29.79  ? 112 LEU A CD1 1 
ATOM   3032 C  CD2 . LEU B 2 116 ? -14.121 -32.643 5.403   1    28.95  ? 112 LEU A CD2 1 
ATOM   3033 N  N   . GLN B 2 117 ? -17.75  -31.094 9.253   1    36.16  ? 113 GLN A N   1 
ATOM   3034 C  CA  . GLN B 2 117 ? -18.962 -30.346 9.549   1    35.05  ? 113 GLN A CA  1 
ATOM   3035 C  C   . GLN B 2 117 ? -18.618 -28.887 9.799   1    35.41  ? 113 GLN A C   1 
ATOM   3036 O  O   . GLN B 2 117 ? -19.305 -28.014 9.302   1    39.98  ? 113 GLN A O   1 
ATOM   3037 C  CB  . GLN B 2 117 ? -19.758 -30.841 10.756  1    34.01  ? 113 GLN A CB  1 
ATOM   3038 C  CG  . GLN B 2 117 ? -20.339 -32.24  10.589  1    34.2   ? 113 GLN A CG  1 
ATOM   3039 C  CD  . GLN B 2 117 ? -21.147 -32.681 11.786  1    37.31  ? 113 GLN A CD  1 
ATOM   3040 O  OE1 . GLN B 2 117 ? -22.044 -31.974 12.278  1    42.91  ? 113 GLN A OE1 1 
ATOM   3041 N  NE2 . GLN B 2 117 ? -20.869 -33.891 12.225  1    37.97  ? 113 GLN A NE2 1 
ATOM   3042 N  N   . GLY B 2 118 ? -17.566 -28.632 10.589  1    41.66  ? 114 GLY A N   1 
ATOM   3043 C  CA  . GLY B 2 118 ? -17.147 -27.276 10.92   1    38.98  ? 114 GLY A CA  1 
ATOM   3044 C  C   . GLY B 2 118 ? -16.77  -26.495 9.665   1    38.91  ? 114 GLY A C   1 
ATOM   3045 O  O   . GLY B 2 118 ? -17.2   -25.362 9.472   1    39.77  ? 114 GLY A O   1 
ATOM   3046 N  N   . LEU B 2 119 ? -16.003 -27.146 8.794   1    38.1   ? 115 LEU A N   1 
ATOM   3047 C  CA  . LEU B 2 119 ? -15.476 -26.511 7.6     1    37.99  ? 115 LEU A CA  1 
ATOM   3048 C  C   . LEU B 2 119 ? -16.59  -26.256 6.583   1    37.14  ? 115 LEU A C   1 
ATOM   3049 O  O   . LEU B 2 119 ? -16.673 -25.146 6.051   1    37.88  ? 115 LEU A O   1 
ATOM   3050 C  CB  . LEU B 2 119 ? -14.364 -27.393 7.045   1    36.82  ? 115 LEU A CB  1 
ATOM   3051 C  CG  . LEU B 2 119 ? -13.529 -26.742 5.947   1    40.22  ? 115 LEU A CG  1 
ATOM   3052 C  CD1 . LEU B 2 119 ? -12.94  -25.406 6.432   1    35.33  ? 115 LEU A CD1 1 
ATOM   3053 C  CD2 . LEU B 2 119 ? -12.435 -27.714 5.533   1    38.99  ? 115 LEU A CD2 1 
ATOM   3054 N  N   . ALA B 2 120 ? -17.453 -27.265 6.347   1    32.83  ? 116 ALA A N   1 
ATOM   3055 C  CA  . ALA B 2 120 ? -18.657 -27.073 5.544   1    30.51  ? 116 ALA A CA  1 
ATOM   3056 C  C   . ALA B 2 120 ? -19.403 -25.81  5.989   1    30.94  ? 116 ALA A C   1 
ATOM   3057 O  O   . ALA B 2 120 ? -19.806 -25.005 5.161   1    32.41  ? 116 ALA A O   1 
ATOM   3058 C  CB  . ALA B 2 120 ? -19.55  -28.283 5.575   1    28.33  ? 116 ALA A CB  1 
ATOM   3059 N  N   . PHE B 2 121 ? -19.533 -25.607 7.3     1    30.25  ? 117 PHE A N   1 
ATOM   3060 C  CA  . PHE B 2 121 ? -20.286 -24.484 7.823   1    33.55  ? 117 PHE A CA  1 
ATOM   3061 C  C   . PHE B 2 121 ? -19.582 -23.16  7.481   1    36.49  ? 117 PHE A C   1 
ATOM   3062 O  O   . PHE B 2 121 ? -20.224 -22.233 7       1    40.37  ? 117 PHE A O   1 
ATOM   3063 C  CB  . PHE B 2 121 ? -20.567 -24.707 9.316   1    31.94  ? 117 PHE A CB  1 
ATOM   3064 C  CG  . PHE B 2 121 ? -21.499 -23.644 9.869   1    33.51  ? 117 PHE A CG  1 
ATOM   3065 C  CD1 . PHE B 2 121 ? -21.005 -22.375 10.2    1    32.68  ? 117 PHE A CD1 1 
ATOM   3066 C  CD2 . PHE B 2 121 ? -22.88  -23.879 9.947   1    35     ? 117 PHE A CD2 1 
ATOM   3067 C  CE1 . PHE B 2 121 ? -21.868 -21.383 10.667  1    35.88  ? 117 PHE A CE1 1 
ATOM   3068 C  CE2 . PHE B 2 121 ? -23.756 -22.887 10.402  1    34.99  ? 117 PHE A CE2 1 
ATOM   3069 C  CZ  . PHE B 2 121 ? -23.247 -21.643 10.778  1    37.59  ? 117 PHE A CZ  1 
ATOM   3070 N  N   . CYS B 2 122 ? -18.272 -23.067 7.753   1    34.07  ? 118 CYS A N   1 
ATOM   3071 C  CA  . CYS B 2 122 ? -17.414 -21.981 7.307   1    34.24  ? 118 CYS A CA  1 
ATOM   3072 C  C   . CYS B 2 122 ? -17.608 -21.658 5.823   1    36.03  ? 118 CYS A C   1 
ATOM   3073 O  O   . CYS B 2 122 ? -17.913 -20.518 5.46    1    33.57  ? 118 CYS A O   1 
ATOM   3074 C  CB  . CYS B 2 122 ? -15.95  -22.357 7.476   1    33.59  ? 118 CYS A CB  1 
ATOM   3075 S  SG  . CYS B 2 122 ? -15.445 -22.292 9.213   1    40.44  ? 118 CYS A SG  1 
ATOM   3076 N  N   . HIS B 2 123 ? -17.423 -22.67  4.968   1    34.64  ? 119 HIS A N   1 
ATOM   3077 C  CA  . HIS B 2 123 ? -17.55  -22.471 3.533   1    35.83  ? 119 HIS A CA  1 
ATOM   3078 C  C   . HIS B 2 123 ? -18.967 -22.034 3.143   1    36.83  ? 119 HIS A C   1 
ATOM   3079 O  O   . HIS B 2 123 ? -19.117 -21.227 2.241   1    42.2   ? 119 HIS A O   1 
ATOM   3080 C  CB  . HIS B 2 123 ? -17.048 -23.712 2.787   1    36.13  ? 119 HIS A CB  1 
ATOM   3081 C  CG  . HIS B 2 123 ? -15.592 -23.951 3       1    36.72  ? 119 HIS A CG  1 
ATOM   3082 N  ND1 . HIS B 2 123 ? -14.944 -25.092 2.574   1    38.06  ? 119 HIS A ND1 1 
ATOM   3083 C  CD2 . HIS B 2 123 ? -14.651 -23.161 3.555   1    36.02  ? 119 HIS A CD2 1 
ATOM   3084 C  CE1 . HIS B 2 123 ? -13.658 -24.992 2.893   1    41.19  ? 119 HIS A CE1 1 
ATOM   3085 N  NE2 . HIS B 2 123 ? -13.458 -23.826 3.509   1    37.24  ? 119 HIS A NE2 1 
ATOM   3086 N  N   . SER B 2 124 ? -19.99  -22.577 3.785   1    34.16  ? 120 SER A N   1 
ATOM   3087 C  CA  . SER B 2 124 ? -21.385 -22.178 3.485   1    37.91  ? 120 SER A CA  1 
ATOM   3088 C  C   . SER B 2 124 ? -21.637 -20.738 3.955   1    39.22  ? 120 SER A C   1 
ATOM   3089 O  O   . SER B 2 124 ? -22.694 -20.188 3.615   1    36.93  ? 120 SER A O   1 
ATOM   3090 C  CB  . SER B 2 124 ? -22.346 -23.141 4.102   1    37.58  ? 120 SER A CB  1 
ATOM   3091 O  OG  . SER B 2 124 ? -22.019 -24.479 3.762   1    41.12  ? 120 SER A OG  1 
ATOM   3092 N  N   . HIS B 2 125 ? -20.689 -20.155 4.691   1    39.26  ? 121 HIS A N   1 
ATOM   3093 C  CA  . HIS B 2 125 ? -20.821 -18.767 5.209   1    38.77  ? 121 HIS A CA  1 
ATOM   3094 C  C   . HIS B 2 125 ? -19.676 -17.926 4.65    1    38.97  ? 121 HIS A C   1 
ATOM   3095 O  O   . HIS B 2 125 ? -19.225 -17.015 5.357   1    37.19  ? 121 HIS A O   1 
ATOM   3096 C  CB  . HIS B 2 125 ? -20.929 -18.78  6.734   1    36.93  ? 121 HIS A CB  1 
ATOM   3097 C  CG  . HIS B 2 125 ? -22.201 -19.397 7.191   1    40.48  ? 121 HIS A CG  1 
ATOM   3098 N  ND1 . HIS B 2 125 ? -22.433 -20.752 7.125   1    41.21  ? 121 HIS A ND1 1 
ATOM   3099 C  CD2 . HIS B 2 125 ? -23.311 -18.856 7.68    1    41.66  ? 121 HIS A CD2 1 
ATOM   3100 C  CE1 . HIS B 2 125 ? -23.651 -21.005 7.563   1    43.54  ? 121 HIS A CE1 1 
ATOM   3101 N  NE2 . HIS B 2 125 ? -24.199 -19.867 7.914   1    44.24  ? 121 HIS A NE2 1 
ATOM   3102 N  N   . ARG B 2 126 ? -19.246 -18.219 3.423   1    34.04  ? 122 ARG A N   1 
ATOM   3103 C  CA  . ARG B 2 126 ? -18.179 -17.461 2.716   1    33.15  ? 122 ARG A CA  1 
ATOM   3104 C  C   . ARG B 2 126 ? -16.974 -17.179 3.625   1    33.77  ? 122 ARG A C   1 
ATOM   3105 O  O   . ARG B 2 126 ? -16.495 -16.044 3.62    1    35.76  ? 122 ARG A O   1 
ATOM   3106 C  CB  . ARG B 2 126 ? -18.729 -16.191 2.059   1    34.05  ? 122 ARG A CB  1 
ATOM   3107 C  CG  . ARG B 2 126 ? -19.927 -15.449 2.626   1    33.82  ? 122 ARG A CG  1 
ATOM   3108 C  CD  . ARG B 2 126 ? -19.497 -14.048 2.976   1    36.77  ? 122 ARG A CD  1 
ATOM   3109 N  NE  . ARG B 2 126 ? -18.918 -13.981 4.32    1    48.85  ? 122 ARG A NE  1 
ATOM   3110 C  CZ  . ARG B 2 126 ? -19.602 -13.695 5.416   1    47.57  ? 122 ARG A CZ  1 
ATOM   3111 N  NH1 . ARG B 2 126 ? -19.54  -14.501 6.457   1    44.73  ? 122 ARG A NH1 1 
ATOM   3112 N  NH2 . ARG B 2 126 ? -20.347 -12.608 5.468   1    43.72  ? 122 ARG A NH2 1 
ATOM   3113 N  N   . VAL B 2 127 ? -16.456 -18.209 4.289   1    32.73  ? 123 VAL A N   1 
ATOM   3114 C  CA  . VAL B 2 127 ? -15.256 -18.016 5.152   1    33.19  ? 123 VAL A CA  1 
ATOM   3115 C  C   . VAL B 2 127 ? -14.173 -19.091 4.965   1    34.89  ? 123 VAL A C   1 
ATOM   3116 O  O   . VAL B 2 127 ? -14.446 -20.26  5.26    1    37.81  ? 123 VAL A O   1 
ATOM   3117 C  CB  . VAL B 2 127 ? -15.609 -17.851 6.648   1    33.53  ? 123 VAL A CB  1 
ATOM   3118 C  CG1 . VAL B 2 127 ? -14.396 -18.03  7.552   1    29.84  ? 123 VAL A CG1 1 
ATOM   3119 C  CG2 . VAL B 2 127 ? -16.277 -16.515 6.938   1    30.04  ? 123 VAL A CG2 1 
ATOM   3120 N  N   . LEU B 2 128 ? -13.02  -18.716 4.422   1    34.63  ? 124 LEU A N   1 
ATOM   3121 C  CA  . LEU B 2 128 ? -11.814 -19.54  4.421   1    34.48  ? 124 LEU A CA  1 
ATOM   3122 C  C   . LEU B 2 128 ? -11.117 -19.466 5.786   1    36.76  ? 124 LEU A C   1 
ATOM   3123 O  O   . LEU B 2 128 ? -10.903 -18.375 6.325   1    39.8   ? 124 LEU A O   1 
ATOM   3124 C  CB  . LEU B 2 128 ? -10.842 -19.044 3.344   1    33.81  ? 124 LEU A CB  1 
ATOM   3125 C  CG  . LEU B 2 128 ? -11.312 -19.074 1.888   1    34.4   ? 124 LEU A CG  1 
ATOM   3126 C  CD1 . LEU B 2 128 ? -10.156 -18.731 0.975   1    35.87  ? 124 LEU A CD1 1 
ATOM   3127 C  CD2 . LEU B 2 128 ? -11.786 -20.446 1.506   1    31.34  ? 124 LEU A CD2 1 
ATOM   3128 N  N   . HIS B 2 129 ? -10.672 -20.618 6.306   1    33.82  ? 125 HIS A N   1 
ATOM   3129 C  CA  . HIS B 2 129 ? -9.896  -20.635 7.532   1    35.45  ? 125 HIS A CA  1 
ATOM   3130 C  C   . HIS B 2 129 ? -8.415  -20.296 7.279   1    36.46  ? 125 HIS A C   1 
ATOM   3131 O  O   . HIS B 2 129 ? -7.884  -19.352 7.876   1    36.88  ? 125 HIS A O   1 
ATOM   3132 C  CB  . HIS B 2 129 ? -10.103 -21.968 8.251   1    36.59  ? 125 HIS A CB  1 
ATOM   3133 C  CG  . HIS B 2 129 ? -9.478  -21.997 9.612   1    37.4   ? 125 HIS A CG  1 
ATOM   3134 N  ND1 . HIS B 2 129 ? -8.12   -22.188 9.783   1    33.8   ? 125 HIS A ND1 1 
ATOM   3135 C  CD2 . HIS B 2 129 ? -9.99   -21.837 10.846  1    33.81  ? 125 HIS A CD2 1 
ATOM   3136 C  CE1 . HIS B 2 129 ? -7.828  -22.128 11.084  1    32.4   ? 125 HIS A CE1 1 
ATOM   3137 N  NE2 . HIS B 2 129 ? -8.941  -21.936 11.75   1    33.94  ? 125 HIS A NE2 1 
ATOM   3138 N  N   . ARG B 2 130 ? -7.722  -21.103 6.457   1    32.64  ? 126 ARG A N   1 
ATOM   3139 C  CA  . ARG B 2 130 ? -6.405  -20.74  5.937   1    33.84  ? 126 ARG A CA  1 
ATOM   3140 C  C   . ARG B 2 130 ? -5.293  -20.999 6.959   1    34.99  ? 126 ARG A C   1 
ATOM   3141 O  O   . ARG B 2 130 ? -4.188  -20.484 6.819   1    42.17  ? 126 ARG A O   1 
ATOM   3142 C  CB  . ARG B 2 130 ? -6.305  -19.276 5.474   1    31.1   ? 126 ARG A CB  1 
ATOM   3143 C  CG  . ARG B 2 130 ? -7.277  -18.893 4.37    1    31.34  ? 126 ARG A CG  1 
ATOM   3144 C  CD  . ARG B 2 130 ? -6.879  -17.642 3.587   1    34.66  ? 126 ARG A CD  1 
ATOM   3145 N  NE  . ARG B 2 130 ? -6.981  -16.447 4.432   1    35.34  ? 126 ARG A NE  1 
ATOM   3146 C  CZ  . ARG B 2 130 ? -6.482  -15.262 4.126   1    37.69  ? 126 ARG A CZ  1 
ATOM   3147 N  NH1 . ARG B 2 130 ? -6.035  -15.018 2.913   1    38.19  ? 126 ARG A NH1 1 
ATOM   3148 N  NH2 . ARG B 2 130 ? -6.471  -14.303 5.03    1    37.04  ? 126 ARG A NH2 1 
ATOM   3149 N  N   . ASP B 2 131 ? -5.571  -21.761 8.016   1    35.64  ? 127 ASP A N   1 
ATOM   3150 C  CA  . ASP B 2 131 ? -4.536  -22.149 8.972   1    35.96  ? 127 ASP A CA  1 
ATOM   3151 C  C   . ASP B 2 131 ? -4.995  -23.413 9.704   1    36.44  ? 127 ASP A C   1 
ATOM   3152 O  O   . ASP B 2 131 ? -4.875  -23.52  10.925  1    37.41  ? 127 ASP A O   1 
ATOM   3153 C  CB  . ASP B 2 131 ? -4.168  -21.044 9.962   1    35.6   ? 127 ASP A CB  1 
ATOM   3154 C  CG  . ASP B 2 131 ? -2.751  -21.1   10.541  1    40.53  ? 127 ASP A CG  1 
ATOM   3155 O  OD1 . ASP B 2 131 ? -1.878  -21.776 9.973   1    40.75  ? 127 ASP A OD1 1 
ATOM   3156 O  OD2 . ASP B 2 131 ? -2.515  -20.487 11.589  1    49.11  ? 127 ASP A OD2 1 
ATOM   3157 N  N   . LEU B 2 132 ? -5.563  -24.37  8.971   1    33.68  ? 128 LEU A N   1 
ATOM   3158 C  CA  . LEU B 2 132 ? -5.981  -25.555 9.688   1    36.3   ? 128 LEU A CA  1 
ATOM   3159 C  C   . LEU B 2 132 ? -4.752  -26.426 9.943   1    37.74  ? 128 LEU A C   1 
ATOM   3160 O  O   . LEU B 2 132 ? -4.044  -26.84  9.024   1    39.28  ? 128 LEU A O   1 
ATOM   3161 C  CB  . LEU B 2 132 ? -7.034  -26.26  8.839   1    37.25  ? 128 LEU A CB  1 
ATOM   3162 C  CG  . LEU B 2 132 ? -8.381  -25.544 8.749   1    36.71  ? 128 LEU A CG  1 
ATOM   3163 C  CD1 . LEU B 2 132 ? -9.181  -26.208 7.635   1    32.69  ? 128 LEU A CD1 1 
ATOM   3164 C  CD2 . LEU B 2 132 ? -9.102  -25.58  10.112  1    33.18  ? 128 LEU A CD2 1 
ATOM   3165 N  N   . LYS B 2 133 ? -4.488  -26.639 11.226  1    34.9   ? 129 LYS A N   1 
ATOM   3166 C  CA  . LYS B 2 133 ? -3.344  -27.459 11.668  1    37.37  ? 129 LYS A CA  1 
ATOM   3167 C  C   . LYS B 2 133 ? -3.772  -28.041 13.02   1    42.92  ? 129 LYS A C   1 
ATOM   3168 O  O   . LYS B 2 133 ? -4.661  -27.451 13.645  1    45.7   ? 129 LYS A O   1 
ATOM   3169 C  CB  . LYS B 2 133 ? -2.108  -26.565 11.752  1    34.67  ? 129 LYS A CB  1 
ATOM   3170 C  CG  . LYS B 2 133 ? -2.158  -25.451 12.776  1    36.47  ? 129 LYS A CG  1 
ATOM   3171 C  CD  . LYS B 2 133 ? -0.866  -24.651 12.779  1    38.15  ? 129 LYS A CD  1 
ATOM   3172 C  CE  . LYS B 2 133 ? -0.881  -23.546 13.775  1    39.47  ? 129 LYS A CE  1 
ATOM   3173 N  NZ  . LYS B 2 133 ? 0.375   -22.795 13.754  1    38.33  ? 129 LYS A NZ  1 
ATOM   3174 N  N   . PRO B 2 134 ? -3.206  -29.165 13.5    1    45.32  ? 130 PRO A N   1 
ATOM   3175 C  CA  . PRO B 2 134 ? -3.674  -29.772 14.743  1    42.77  ? 130 PRO A CA  1 
ATOM   3176 C  C   . PRO B 2 134 ? -3.701  -28.895 15.998  1    44.85  ? 130 PRO A C   1 
ATOM   3177 O  O   . PRO B 2 134 ? -4.497  -29.168 16.902  1    45.64  ? 130 PRO A O   1 
ATOM   3178 C  CB  . PRO B 2 134 ? -2.668  -30.914 14.848  1    40.51  ? 130 PRO A CB  1 
ATOM   3179 C  CG  . PRO B 2 134 ? -2.378  -31.277 13.422  1    40.75  ? 130 PRO A CG  1 
ATOM   3180 C  CD  . PRO B 2 134 ? -2.156  -29.905 12.842  1    40.68  ? 130 PRO A CD  1 
ATOM   3181 N  N   . GLN B 2 135 ? -2.866  -27.865 16.048  1    41.95  ? 131 GLN A N   1 
ATOM   3182 C  CA  . GLN B 2 135 ? -2.786  -26.951 17.208  1    45.11  ? 131 GLN A CA  1 
ATOM   3183 C  C   . GLN B 2 135 ? -3.931  -25.937 17.176  1    45.9   ? 131 GLN A C   1 
ATOM   3184 O  O   . GLN B 2 135 ? -4.101  -25.214 18.168  1    46.76  ? 131 GLN A O   1 
ATOM   3185 C  CB  . GLN B 2 135 ? -1.455  -26.227 17.067  1    49.84  ? 131 GLN A CB  1 
ATOM   3186 C  CG  . GLN B 2 135 ? -0.236  -27.139 17.129  1    63.43  ? 131 GLN A CG  1 
ATOM   3187 C  CD  . GLN B 2 135 ? 0.3     -27.548 15.774  1    67.7   ? 131 GLN A CD  1 
ATOM   3188 O  OE1 . GLN B 2 135 ? -0.431  -27.64  14.784  1    54.31  ? 131 GLN A OE1 1 
ATOM   3189 N  NE2 . GLN B 2 135 ? 1.596   -27.813 15.723  1    69.25  ? 131 GLN A NE2 1 
ATOM   3190 N  N   . ASN B 2 136 ? -4.669  -25.883 16.07   1    40.73  ? 132 ASN A N   1 
ATOM   3191 C  CA  . ASN B 2 136 ? -5.803  -24.936 15.924  1    38.95  ? 132 ASN A CA  1 
ATOM   3192 C  C   . ASN B 2 136 ? -7.104  -25.731 16.035  1    39.12  ? 132 ASN A C   1 
ATOM   3193 O  O   . ASN B 2 136 ? -8.155  -25.161 15.743  1    38.86  ? 132 ASN A O   1 
ATOM   3194 C  CB  . ASN B 2 136 ? -5.641  -24.116 14.651  1    36.65  ? 132 ASN A CB  1 
ATOM   3195 C  CG  . ASN B 2 136 ? -4.596  -23.037 14.771  1    37.68  ? 132 ASN A CG  1 
ATOM   3196 O  OD1 . ASN B 2 136 ? -4.057  -22.809 15.857  1    39.6   ? 132 ASN A OD1 1 
ATOM   3197 N  ND2 . ASN B 2 136 ? -4.3    -22.362 13.672  1    37.78  ? 132 ASN A ND2 1 
ATOM   3198 N  N   . LEU B 2 137 ? -7.021  -27.003 16.424  1    35.14  ? 133 LEU A N   1 
ATOM   3199 C  CA  . LEU B 2 137 ? -8.182  -27.848 16.612  1    34.95  ? 133 LEU A CA  1 
ATOM   3200 C  C   . LEU B 2 137 ? -8.287  -28.235 18.079  1    37.17  ? 133 LEU A C   1 
ATOM   3201 O  O   . LEU B 2 137 ? -7.49   -29.034 18.568  1    40.11  ? 133 LEU A O   1 
ATOM   3202 C  CB  . LEU B 2 137 ? -7.975  -29.083 15.743  1    34.43  ? 133 LEU A CB  1 
ATOM   3203 C  CG  . LEU B 2 137 ? -7.649  -28.795 14.275  1    33.75  ? 133 LEU A CG  1 
ATOM   3204 C  CD1 . LEU B 2 137 ? -7.713  -30.11  13.475  1    33.47  ? 133 LEU A CD1 1 
ATOM   3205 C  CD2 . LEU B 2 137 ? -8.568  -27.701 13.708  1    29.2   ? 133 LEU A CD2 1 
ATOM   3206 N  N   . LEU B 2 138 ? -9.293  -27.686 18.763  1    37.54  ? 134 LEU A N   1 
ATOM   3207 C  CA  . LEU B 2 138 ? -9.455  -27.916 20.189  1    39.01  ? 134 LEU A CA  1 
ATOM   3208 C  C   . LEU B 2 138 ? -10.42  -29.081 20.446  1    40.32  ? 134 LEU A C   1 
ATOM   3209 O  O   . LEU B 2 138 ? -11.41  -29.228 19.742  1    44.57  ? 134 LEU A O   1 
ATOM   3210 C  CB  . LEU B 2 138 ? -9.907  -26.572 20.767  1    39.14  ? 134 LEU A CB  1 
ATOM   3211 C  CG  . LEU B 2 138 ? -8.965  -25.377 20.503  1    39.76  ? 134 LEU A CG  1 
ATOM   3212 C  CD1 . LEU B 2 138 ? -9.392  -24.122 21.236  1    35.67  ? 134 LEU A CD1 1 
ATOM   3213 C  CD2 . LEU B 2 138 ? -7.466  -25.609 20.781  1    38.41  ? 134 LEU A CD2 1 
ATOM   3214 N  N   . ILE B 2 139 ? -10.109 -29.928 21.437  1    39.62  ? 135 ILE A N   1 
ATOM   3215 C  CA  . ILE B 2 139 ? -10.969 -31.015 21.87   1    39.58  ? 135 ILE A CA  1 
ATOM   3216 C  C   . ILE B 2 139 ? -11.388 -30.786 23.322  1    43.54  ? 135 ILE A C   1 
ATOM   3217 O  O   . ILE B 2 139 ? -10.663 -30.171 24.103  1    45.89  ? 135 ILE A O   1 
ATOM   3218 C  CB  . ILE B 2 139 ? -10.25  -32.369 21.709  1    40.76  ? 135 ILE A CB  1 
ATOM   3219 C  CG1 . ILE B 2 139 ? -9.215  -32.599 22.766  1    45.8   ? 135 ILE A CG1 1 
ATOM   3220 C  CG2 . ILE B 2 139 ? -9.594  -32.5   20.342  1    37.25  ? 135 ILE A CG2 1 
ATOM   3221 C  CD1 . ILE B 2 139 ? -8.208  -33.673 22.373  1    47.22  ? 135 ILE A CD1 1 
ATOM   3222 N  N   . ASN B 2 140 ? -12.553 -31.317 23.71   1    45.2   ? 136 ASN A N   1 
ATOM   3223 C  CA  . ASN B 2 140 ? -13.019 -31.189 25.087  1    48.74  ? 136 ASN A CA  1 
ATOM   3224 C  C   . ASN B 2 140 ? -13.094 -32.571 25.74   1    52.05  ? 136 ASN A C   1 
ATOM   3225 O  O   . ASN B 2 140 ? -12.684 -33.565 25.15   1    54.2   ? 136 ASN A O   1 
ATOM   3226 C  CB  . ASN B 2 140 ? -14.319 -30.39  25.195  1    46.13  ? 136 ASN A CB  1 
ATOM   3227 C  CG  . ASN B 2 140 ? -15.501 -31.113 24.585  1    45.92  ? 136 ASN A CG  1 
ATOM   3228 O  OD1 . ASN B 2 140 ? -15.485 -32.337 24.384  1    43.83  ? 136 ASN A OD1 1 
ATOM   3229 N  ND2 . ASN B 2 140 ? -16.537 -30.362 24.246  1    45.2   ? 136 ASN A ND2 1 
ATOM   3230 N  N   . THR B 2 141 ? -13.652 -32.633 26.952  1    54.57  ? 137 THR A N   1 
ATOM   3231 C  CA  . THR B 2 141 ? -13.662 -33.882 27.702  1    58.34  ? 137 THR A CA  1 
ATOM   3232 C  C   . THR B 2 141 ? -14.721 -34.858 27.164  1    62.16  ? 137 THR A C   1 
ATOM   3233 O  O   . THR B 2 141 ? -14.649 -36.05  27.462  1    67.73  ? 137 THR A O   1 
ATOM   3234 C  CB  . THR B 2 141 ? -13.828 -33.566 29.19   1    59.35  ? 137 THR A CB  1 
ATOM   3235 O  OG1 . THR B 2 141 ? -14.814 -32.546 29.261  1    57.13  ? 137 THR A OG1 1 
ATOM   3236 C  CG2 . THR B 2 141 ? -12.595 -32.916 29.787  1    63.69  ? 137 THR A CG2 1 
ATOM   3237 N  N   . GLU B 2 142 ? -15.646 -34.353 26.331  1    59.82  ? 138 GLU A N   1 
ATOM   3238 C  CA  . GLU B 2 142 ? -16.854 -35.033 25.879  1    62.41  ? 138 GLU A CA  1 
ATOM   3239 C  C   . GLU B 2 142 ? -16.67  -35.696 24.507  1    63.66  ? 138 GLU A C   1 
ATOM   3240 O  O   . GLU B 2 142 ? -17.609 -36.33  24.007  1    68.85  ? 138 GLU A O   1 
ATOM   3241 C  CB  . GLU B 2 142 ? -17.998 -34.041 25.627  1    61.29  ? 138 GLU A CB  1 
ATOM   3242 C  CG  . GLU B 2 142 ? -18.496 -33.288 26.855  1    67.7   ? 138 GLU A CG  1 
ATOM   3243 C  CD  . GLU B 2 142 ? -19.079 -34.171 27.945  1    77.97  ? 138 GLU A CD  1 
ATOM   3244 O  OE1 . GLU B 2 142 ? -19.826 -35.136 27.639  1    78.34  ? 138 GLU A OE1 1 
ATOM   3245 O  OE2 . GLU B 2 142 ? -18.798 -33.859 29.124  1    80.18  ? 138 GLU A OE2 1 
ATOM   3246 N  N   . GLY B 2 143 ? -15.521 -35.464 23.851  1    55.37  ? 139 GLY A N   1 
ATOM   3247 C  CA  . GLY B 2 143 ? -15.262 -36.03  22.534  1    47.56  ? 139 GLY A CA  1 
ATOM   3248 C  C   . GLY B 2 143 ? -15.515 -35.048 21.387  1    42.45  ? 139 GLY A C   1 
ATOM   3249 O  O   . GLY B 2 143 ? -15.481 -35.442 20.218  1    38.47  ? 139 GLY A O   1 
ATOM   3250 N  N   . ALA B 2 144 ? -15.802 -33.783 21.711  1    38.6   ? 140 ALA A N   1 
ATOM   3251 C  CA  . ALA B 2 144 ? -15.975 -32.803 20.653  1    38.53  ? 140 ALA A CA  1 
ATOM   3252 C  C   . ALA B 2 144 ? -14.608 -32.322 20.142  1    41.61  ? 140 ALA A C   1 
ATOM   3253 O  O   . ALA B 2 144 ? -13.602 -32.385 20.854  1    42.6   ? 140 ALA A O   1 
ATOM   3254 C  CB  . ALA B 2 144 ? -16.8   -31.67  21.187  1    36.37  ? 140 ALA A CB  1 
ATOM   3255 N  N   . ILE B 2 145 ? -14.565 -31.875 18.881  1    39.95  ? 141 ILE A N   1 
ATOM   3256 C  CA  . ILE B 2 145 ? -13.394 -31.213 18.325  1    39.06  ? 141 ILE A CA  1 
ATOM   3257 C  C   . ILE B 2 145 ? -13.852 -30.043 17.45   1    38.77  ? 141 ILE A C   1 
ATOM   3258 O  O   . ILE B 2 145 ? -14.839 -30.131 16.739  1    33.6   ? 141 ILE A O   1 
ATOM   3259 C  CB  . ILE B 2 145 ? -12.487 -32.197 17.576  1    38.57  ? 141 ILE A CB  1 
ATOM   3260 C  CG1 . ILE B 2 145 ? -11.212 -31.524 17.072  1    41.3   ? 141 ILE A CG1 1 
ATOM   3261 C  CG2 . ILE B 2 145 ? -13.264 -32.849 16.436  1    40.93  ? 141 ILE A CG2 1 
ATOM   3262 C  CD1 . ILE B 2 145 ? -10.118 -32.49  16.651  1    40.14  ? 141 ILE A CD1 1 
ATOM   3263 N  N   . LYS B 2 146 ? -13.144 -28.913 17.546  1    40.32  ? 142 LYS A N   1 
ATOM   3264 C  CA  . LYS B 2 146 ? -13.7   -27.668 17.053  1    39.17  ? 142 LYS A CA  1 
ATOM   3265 C  C   . LYS B 2 146 ? -12.591 -26.849 16.416  1    40.82  ? 142 LYS A C   1 
ATOM   3266 O  O   . LYS B 2 146 ? -11.458 -26.864 16.898  1    44.88  ? 142 LYS A O   1 
ATOM   3267 C  CB  . LYS B 2 146 ? -14.306 -26.9   18.227  1    39.33  ? 142 LYS A CB  1 
ATOM   3268 C  CG  . LYS B 2 146 ? -15.26  -27.722 19.063  1    38.82  ? 142 LYS A CG  1 
ATOM   3269 C  CD  . LYS B 2 146 ? -16.242 -26.855 19.843  1    39.72  ? 142 LYS A CD  1 
ATOM   3270 C  CE  . LYS B 2 146 ? -17.118 -27.645 20.789  1    38.93  ? 142 LYS A CE  1 
ATOM   3271 N  NZ  . LYS B 2 146 ? -18.19  -26.786 21.305  1    42.95  ? 142 LYS A NZ  1 
ATOM   3272 N  N   . LEU B 2 147 ? -12.929 -26.173 15.316  1    38.77  ? 143 LEU A N   1 
ATOM   3273 C  CA  . LEU B 2 147 ? -11.966 -25.34  14.625  1    37.87  ? 143 LEU A CA  1 
ATOM   3274 C  C   . LEU B 2 147 ? -11.723 -24.134 15.52   1    37.78  ? 143 LEU A C   1 
ATOM   3275 O  O   . LEU B 2 147 ? -12.662 -23.531 16      1    41.43  ? 143 LEU A O   1 
ATOM   3276 C  CB  . LEU B 2 147 ? -12.461 -24.879 13.248  1    37.79  ? 143 LEU A CB  1 
ATOM   3277 C  CG  . LEU B 2 147 ? -13.071 -25.901 12.277  1    39.67  ? 143 LEU A CG  1 
ATOM   3278 C  CD1 . LEU B 2 147 ? -13.075 -25.225 10.905  1    37.12  ? 143 LEU A CD1 1 
ATOM   3279 C  CD2 . LEU B 2 147 ? -12.362 -27.237 12.172  1    38.26  ? 143 LEU A CD2 1 
ATOM   3280 N  N   . ALA B 2 148 ? -10.467 -23.737 15.677  1    38.45  ? 144 ALA A N   1 
ATOM   3281 C  CA  . ALA B 2 148 ? -10.142 -22.498 16.376  1    37.64  ? 144 ALA A CA  1 
ATOM   3282 C  C   . ALA B 2 148 ? -9.163  -21.67  15.538  1    39.73  ? 144 ALA A C   1 
ATOM   3283 O  O   . ALA B 2 148 ? -8.7    -22.091 14.46   1    39.02  ? 144 ALA A O   1 
ATOM   3284 C  CB  . ALA B 2 148 ? -9.581  -22.811 17.758  1    31.74  ? 144 ALA A CB  1 
ATOM   3285 N  N   . ASP B 2 149 ? -8.859  -20.494 16.092  1    41.04  ? 145 ASP A N   1 
ATOM   3286 C  CA  . ASP B 2 149 ? -7.885  -19.524 15.625  1    42.31  ? 145 ASP A CA  1 
ATOM   3287 C  C   . ASP B 2 149 ? -8.275  -19.046 14.244  1    39.3   ? 145 ASP A C   1 
ATOM   3288 O  O   . ASP B 2 149 ? -7.791  -19.593 13.267  1    39.3   ? 145 ASP A O   1 
ATOM   3289 C  CB  . ASP B 2 149 ? -6.452  -20.016 15.709  1    45.94  ? 145 ASP A CB  1 
ATOM   3290 C  CG  . ASP B 2 149 ? -5.394  -18.908 15.778  1    56.79  ? 145 ASP A CG  1 
ATOM   3291 O  OD1 . ASP B 2 149 ? -5.718  -17.735 15.475  1    53.12  ? 145 ASP A OD1 1 
ATOM   3292 O  OD2 . ASP B 2 149 ? -4.236  -19.21  16.169  1    67.87  ? 145 ASP A OD2 1 
ATOM   3293 N  N   . PHE B 2 150 ? -9.097  -17.999 14.2    1    39.03  ? 146 PHE A N   1 
ATOM   3294 C  CA  . PHE B 2 150 ? -9.611  -17.458 12.917  1    39.56  ? 146 PHE A CA  1 
ATOM   3295 C  C   . PHE B 2 150 ? -8.959  -16.11  12.608  1    42.49  ? 146 PHE A C   1 
ATOM   3296 O  O   . PHE B 2 150 ? -9.583  -15.286 11.929  1    40.64  ? 146 PHE A O   1 
ATOM   3297 C  CB  . PHE B 2 150 ? -11.131 -17.387 13.062  1    38.74  ? 146 PHE A CB  1 
ATOM   3298 C  CG  . PHE B 2 150 ? -11.899 -18.677 12.82   1    34.18  ? 146 PHE A CG  1 
ATOM   3299 C  CD1 . PHE B 2 150 ? -11.962 -19.665 13.794  1    31.29  ? 146 PHE A CD1 1 
ATOM   3300 C  CD2 . PHE B 2 150 ? -12.574 -18.887 11.626  1    30.05  ? 146 PHE A CD2 1 
ATOM   3301 C  CE1 . PHE B 2 150 ? -12.666 -20.834 13.571  1    31.17  ? 146 PHE A CE1 1 
ATOM   3302 C  CE2 . PHE B 2 150 ? -13.278 -20.058 11.41   1    28.86  ? 146 PHE A CE2 1 
ATOM   3303 C  CZ  . PHE B 2 150 ? -13.322 -21.027 12.382  1    29.86  ? 146 PHE A CZ  1 
ATOM   3304 N  N   . GLY B 2 151 ? -7.724  -15.907 13.067  1    43.16  ? 147 GLY A N   1 
ATOM   3305 C  CA  . GLY B 2 151 ? -6.982  -14.663 12.794  1    44.53  ? 147 GLY A CA  1 
ATOM   3306 C  C   . GLY B 2 151 ? -6.432  -14.632 11.388  1    45.07  ? 147 GLY A C   1 
ATOM   3307 O  O   . GLY B 2 151 ? -6.194  -13.529 10.878  1    47.35  ? 147 GLY A O   1 
ATOM   3308 N  N   . LEU B 2 152 ? -6.25   -15.797 10.776  1    42.32  ? 148 LEU A N   1 
ATOM   3309 C  CA  . LEU B 2 152 ? -5.799  -15.865 9.365   1    47.5   ? 148 LEU A CA  1 
ATOM   3310 C  C   . LEU B 2 152 ? -7.005  -16.108 8.446   1    45.32  ? 148 LEU A C   1 
ATOM   3311 O  O   . LEU B 2 152 ? -6.782  -16.35  7.259   1    46.7   ? 148 LEU A O   1 
ATOM   3312 C  CB  . LEU B 2 152 ? -4.769  -16.985 9.252   1    48.34  ? 148 LEU A CB  1 
ATOM   3313 C  CG  . LEU B 2 152 ? -3.462  -16.781 10.018  1    57.17  ? 148 LEU A CG  1 
ATOM   3314 C  CD1 . LEU B 2 152 ? -2.626  -18.039 9.916   1    55.25  ? 148 LEU A CD1 1 
ATOM   3315 C  CD2 . LEU B 2 152 ? -2.709  -15.593 9.45    1    63.7   ? 148 LEU A CD2 1 
ATOM   3316 N  N   . ALA B 2 153 ? -8.227  -16.055 8.987   1    38.81  ? 149 ALA A N   1 
ATOM   3317 C  CA  . ALA B 2 153 ? -9.381  -16.35  8.156   1    39.32  ? 149 ALA A CA  1 
ATOM   3318 C  C   . ALA B 2 153 ? -9.723  -15.177 7.231   1    39.78  ? 149 ALA A C   1 
ATOM   3319 O  O   . ALA B 2 153 ? -9.211  -14.065 7.393   1    39.04  ? 149 ALA A O   1 
ATOM   3320 C  CB  . ALA B 2 153 ? -10.527 -16.718 9.073   1    39.81  ? 149 ALA A CB  1 
ATOM   3321 N  N   . ARG B 2 154 ? -10.543 -15.457 6.223   1    37.44  ? 150 ARG A N   1 
ATOM   3322 C  CA  . ARG B 2 154 ? -10.938 -14.372 5.299   1    41.03  ? 150 ARG A CA  1 
ATOM   3323 C  C   . ARG B 2 154 ? -12.331 -14.542 4.7     1    42.99  ? 150 ARG A C   1 
ATOM   3324 O  O   . ARG B 2 154 ? -12.631 -15.628 4.188   1    45.13  ? 150 ARG A O   1 
ATOM   3325 C  CB  . ARG B 2 154 ? -10.042 -14.247 4.066   1    39.31  ? 150 ARG A CB  1 
ATOM   3326 C  CG  . ARG B 2 154 ? -9.584  -12.817 3.836   1    39.06  ? 150 ARG A CG  1 
ATOM   3327 C  CD  . ARG B 2 154 ? -9.715  -12.443 2.382   1    45.24  ? 150 ARG A CD  1 
ATOM   3328 N  NE  . ARG B 2 154 ? -8.572  -11.624 1.972   1    49.59  ? 150 ARG A NE  1 
ATOM   3329 C  CZ  . ARG B 2 154 ? -8.662  -10.357 1.614   1    48.49  ? 150 ARG A CZ  1 
ATOM   3330 N  NH1 . ARG B 2 154 ? -7.577  -9.685  1.286   1    44.56  ? 150 ARG A NH1 1 
ATOM   3331 N  NH2 . ARG B 2 154 ? -9.84   -9.768  1.584   1    49.57  ? 150 ARG A NH2 1 
ATOM   3332 N  N   . ALA B 2 155 ? -13.146 -13.492 4.78    1    39.07  ? 151 ALA A N   1 
ATOM   3333 C  CA  . ALA B 2 155 ? -14.413 -13.473 4.067   1    38.31  ? 151 ALA A CA  1 
ATOM   3334 C  C   . ALA B 2 155 ? -14.197 -13.412 2.549   1    37.68  ? 151 ALA A C   1 
ATOM   3335 O  O   . ALA B 2 155 ? -13.689 -12.427 2.02    1    41.72  ? 151 ALA A O   1 
ATOM   3336 C  CB  . ALA B 2 155 ? -15.245 -12.318 4.576   1    35.88  ? 151 ALA A CB  1 
ATOM   3337 N  N   . PHE B 2 156 ? -14.634 -14.45  1.833   1    35.34  ? 152 PHE A N   1 
ATOM   3338 C  CA  . PHE B 2 156 ? -14.439 -14.484 0.391   1    35.64  ? 152 PHE A CA  1 
ATOM   3339 C  C   . PHE B 2 156 ? -15.7   -14.079 -0.368  1    39.19  ? 152 PHE A C   1 
ATOM   3340 O  O   . PHE B 2 156 ? -16.803 -13.995 0.189   1    44.1   ? 152 PHE A O   1 
ATOM   3341 C  CB  . PHE B 2 156 ? -13.897 -15.819 -0.111  1    36.32  ? 152 PHE A CB  1 
ATOM   3342 C  CG  . PHE B 2 156 ? -14.741 -17.079 -0.005  1    38.38  ? 152 PHE A CG  1 
ATOM   3343 C  CD1 . PHE B 2 156 ? -15.575 -17.476 -1.061  1    40.82  ? 152 PHE A CD1 1 
ATOM   3344 C  CD2 . PHE B 2 156 ? -14.65  -17.907 1.11    1    36.97  ? 152 PHE A CD2 1 
ATOM   3345 C  CE1 . PHE B 2 156 ? -16.299 -18.674 -1.016  1    37.54  ? 152 PHE A CE1 1 
ATOM   3346 C  CE2 . PHE B 2 156 ? -15.411 -19.073 1.178   1    37.17  ? 152 PHE A CE2 1 
ATOM   3347 C  CZ  . PHE B 2 156 ? -16.22  -19.467 0.114   1    35.8   ? 152 PHE A CZ  1 
ATOM   3348 N  N   . GLY B 2 157 ? -15.495 -13.792 -1.659  1    37.92  ? 153 GLY A N   1 
ATOM   3349 C  CA  . GLY B 2 157 ? -16.551 -13.464 -2.599  1    35.83  ? 153 GLY A CA  1 
ATOM   3350 C  C   . GLY B 2 157 ? -16.618 -14.556 -3.658  1    36.78  ? 153 GLY A C   1 
ATOM   3351 O  O   . GLY B 2 157 ? -15.723 -15.412 -3.723  1    35.45  ? 153 GLY A O   1 
ATOM   3352 N  N   . VAL B 2 158 ? -17.693 -14.551 -4.454  1    39.3   ? 154 VAL A N   1 
ATOM   3353 C  CA  . VAL B 2 158 ? -17.886 -15.599 -5.503  1    38.39  ? 154 VAL A CA  1 
ATOM   3354 C  C   . VAL B 2 158 ? -18.013 -14.908 -6.871  1    39.8   ? 154 VAL A C   1 
ATOM   3355 O  O   . VAL B 2 158 ? -19.031 -14.219 -7.086  1    39.47  ? 154 VAL A O   1 
ATOM   3356 C  CB  . VAL B 2 158 ? -19.123 -16.472 -5.216  1    38.46  ? 154 VAL A CB  1 
ATOM   3357 C  CG1 . VAL B 2 158 ? -19.247 -17.624 -6.206  1    42.36  ? 154 VAL A CG1 1 
ATOM   3358 C  CG2 . VAL B 2 158 ? -19.147 -16.981 -3.78   1    37.72  ? 154 VAL A CG2 1 
ATOM   3359 N  N   . PRO B 2 159 ? -17.046 -15.07  -7.803  1    38.42  ? 155 PRO A N   1 
ATOM   3360 C  CA  . PRO B 2 159 ? -15.901 -15.946 -7.583  1    37.83  ? 155 PRO A CA  1 
ATOM   3361 C  C   . PRO B 2 159 ? -14.8   -15.328 -6.726  1    41.99  ? 155 PRO A C   1 
ATOM   3362 O  O   . PRO B 2 159 ? -14.772 -14.091 -6.56   1    43.88  ? 155 PRO A O   1 
ATOM   3363 C  CB  . PRO B 2 159 ? -15.432 -16.22  -9.021  1    36.29  ? 155 PRO A CB  1 
ATOM   3364 C  CG  . PRO B 2 159 ? -15.762 -14.942 -9.756  1    37.27  ? 155 PRO A CG  1 
ATOM   3365 C  CD  . PRO B 2 159 ? -17.045 -14.439 -9.113  1    39.79  ? 155 PRO A CD  1 
ATOM   3366 N  N   . VAL B 2 160 ? -13.911 -16.168 -6.187  1    39.74  ? 156 VAL A N   1 
ATOM   3367 C  CA  . VAL B 2 160 ? -12.834 -15.669 -5.278  1    39.78  ? 156 VAL A CA  1 
ATOM   3368 C  C   . VAL B 2 160 ? -11.873 -14.76  -6.06   1    41.42  ? 156 VAL A C   1 
ATOM   3369 O  O   . VAL B 2 160 ? -11.711 -14.972 -7.285  1    40.04  ? 156 VAL A O   1 
ATOM   3370 C  CB  . VAL B 2 160 ? -12.076 -16.834 -4.612  1    36.47  ? 156 VAL A CB  1 
ATOM   3371 C  CG1 . VAL B 2 160 ? -12.993 -17.676 -3.734  1    33.19  ? 156 VAL A CG1 1 
ATOM   3372 C  CG2 . VAL B 2 160 ? -11.363 -17.709 -5.636  1    32.53  ? 156 VAL A CG2 1 
ATOM   3373 N  N   . ARG B 2 161 ? -11.274 -13.785 -5.383  1    43.23  ? 157 ARG A N   1 
ATOM   3374 C  CA  . ARG B 2 161 ? -10.283 -12.879 -6.013  1    50.65  ? 157 ARG A CA  1 
ATOM   3375 C  C   . ARG B 2 161 ? -8.887  -13.222 -5.463  1    49.71  ? 157 ARG A C   1 
ATOM   3376 O  O   . ARG B 2 161 ? -8.779  -14.218 -4.737  1    46.77  ? 157 ARG A O   1 
ATOM   3377 C  CB  . ARG B 2 161 ? -10.737 -11.436 -5.765  1    49.99  ? 157 ARG A CB  1 
ATOM   3378 C  CG  . ARG B 2 161 ? -10.364 -10.781 -4.447  1    53.42  ? 157 ARG A CG  1 
ATOM   3379 C  CD  . ARG B 2 161 ? -10.872 -9.355  -4.402  1    64.57  ? 157 ARG A CD  1 
ATOM   3380 N  NE  . ARG B 2 161 ? -9.902  -8.47   -3.751  1    70.81  ? 157 ARG A NE  1 
ATOM   3381 C  CZ  . ARG B 2 161 ? -9.735  -8.392  -2.441  1    71.68  ? 157 ARG A CZ  1 
ATOM   3382 N  NH1 . ARG B 2 161 ? -8.524  -8.426  -1.92   1    69.93  ? 157 ARG A NH1 1 
ATOM   3383 N  NH2 . ARG B 2 161 ? -10.787 -8.281  -1.659  1    71.71  ? 157 ARG A NH2 1 
ATOM   3384 N  N   . THR B 2 162 ? -7.859  -12.45  -5.828  1    49.5   ? 158 THR A N   1 
ATOM   3385 C  CA  . THR B 2 162 ? -6.485  -12.744 -5.368  1    49.7   ? 158 THR A CA  1 
ATOM   3386 C  C   . THR B 2 162 ? -6.317  -12.3   -3.933  1    48.15  ? 158 THR A C   1 
ATOM   3387 O  O   . THR B 2 162 ? -6.37   -11.077 -3.684  1    48.56  ? 158 THR A O   1 
ATOM   3388 C  CB  . THR B 2 162 ? -5.469  -12.07  -6.29   1    50.94  ? 158 THR A CB  1 
ATOM   3389 O  OG1 . THR B 2 162 ? -5.741  -12.608 -7.58   1    59.21  ? 158 THR A OG1 1 
ATOM   3390 C  CG2 . THR B 2 162 ? -4.036  -12.367 -5.89   1    46.76  ? 158 THR A CG2 1 
ATOM   3391 N  N   . TYR B 2 163 ? -6.14   -13.25  -3.013  1    45.48  ? 159 TYR A N   1 
ATOM   3392 C  CA  . TYR B 2 163 ? -5.872  -12.915 -1.615  1    46.87  ? 159 TYR A CA  1 
ATOM   3393 C  C   . TYR B 2 163 ? -4.383  -13.051 -1.264  1    46.24  ? 159 TYR A C   1 
ATOM   3394 O  O   . TYR B 2 163 ? -3.538  -13.345 -2.1    1    45.48  ? 159 TYR A O   1 
ATOM   3395 C  CB  . TYR B 2 163 ? -6.768  -13.761 -0.707  1    43.66  ? 159 TYR A CB  1 
ATOM   3396 C  CG  . TYR B 2 163 ? -8.248  -13.711 -1.074  1    46.7   ? 159 TYR A CG  1 
ATOM   3397 C  CD1 . TYR B 2 163 ? -8.949  -12.514 -1.169  1    43.9   ? 159 TYR A CD1 1 
ATOM   3398 C  CD2 . TYR B 2 163 ? -8.928  -14.887 -1.369  1    44.8   ? 159 TYR A CD2 1 
ATOM   3399 C  CE1 . TYR B 2 163 ? -10.279 -12.501 -1.533  1    44.5   ? 159 TYR A CE1 1 
ATOM   3400 C  CE2 . TYR B 2 163 ? -10.263 -14.885 -1.721  1    43.96  ? 159 TYR A CE2 1 
ATOM   3401 C  CZ  . TYR B 2 163 ? -10.945 -13.689 -1.789  1    45.38  ? 159 TYR A CZ  1 
ATOM   3402 O  OH  . TYR B 2 163 ? -12.249 -13.744 -2.208  1    48.66  ? 159 TYR A OH  1 
HETATM 3403 N  N   . TPO B 2 164 ? -4.066  -12.81  0.002   1    47.07  ? 160 TPO A N   1 
HETATM 3404 C  CA  . TPO B 2 164 ? -2.721  -12.917 0.541   1    47.56  ? 160 TPO A CA  1 
HETATM 3405 C  CB  . TPO B 2 164 ? -2.81   -12.857 2.073   1    44.49  ? 160 TPO A CB  1 
HETATM 3406 C  CG2 . TPO B 2 164 ? -1.471  -12.759 2.755   1    39.78  ? 160 TPO A CG2 1 
HETATM 3407 O  OG1 . TPO B 2 164 ? -3.539  -11.619 2.375   1    48.49  ? 160 TPO A OG1 1 
HETATM 3408 P  P   . TPO B 2 164 ? -4.933  -11.565 3.199   1    41.82  ? 160 TPO A P   1 
HETATM 3409 O  O1P . TPO B 2 164 ? -5.947  -12.363 2.393   1    43.08  ? 160 TPO A O1P 1 
HETATM 3410 O  O2P . TPO B 2 164 ? -5.228  -10.084 3.321   1    39.35  ? 160 TPO A O2P 1 
HETATM 3411 O  O3P . TPO B 2 164 ? -4.691  -12.256 4.528   1    40.18  ? 160 TPO A O3P 1 
HETATM 3412 C  C   . TPO B 2 164 ? -2.146  -14.262 0.118   1    48.27  ? 160 TPO A C   1 
HETATM 3413 O  O   . TPO B 2 164 ? -2.838  -15.277 0.292   1    44.12  ? 160 TPO A O   1 
ATOM   3414 N  N   . HIS B 2 165 ? -0.902  -14.23  -0.4    1    49.86  ? 161 HIS A N   1 
ATOM   3415 C  CA  . HIS B 2 165 ? -0.12   -15.406 -0.768  1    59.52  ? 161 HIS A CA  1 
ATOM   3416 C  C   . HIS B 2 165 ? 0.55    -15.967 0.484   1    62.58  ? 161 HIS A C   1 
ATOM   3417 O  O   . HIS B 2 165 ? 0.627   -15.276 1.499   1    73.24  ? 161 HIS A O   1 
ATOM   3418 C  CB  . HIS B 2 165 ? 0.929   -15.027 -1.822  1    64.52  ? 161 HIS A CB  1 
ATOM   3419 C  CG  . HIS B 2 165 ? 1.66    -16.171 -2.474  1    92.66  ? 161 HIS A CG  1 
ATOM   3420 N  ND1 . HIS B 2 165 ? 2.616   -15.925 -3.443  1    112.79 ? 161 HIS A ND1 1 
ATOM   3421 C  CD2 . HIS B 2 165 ? 1.586   -17.518 -2.381  1    88.21  ? 161 HIS A CD2 1 
ATOM   3422 C  CE1 . HIS B 2 165 ? 3.129   -17.071 -3.876  1    107.96 ? 161 HIS A CE1 1 
ATOM   3423 N  NE2 . HIS B 2 165 ? 2.517   -18.052 -3.24   1    99.66  ? 161 HIS A NE2 1 
ATOM   3424 N  N   . GLU B 2 166 ? 1.062   -17.207 0.44    1    68.59  ? 162 GLU A N   1 
ATOM   3425 C  CA  . GLU B 2 166 ? 1.824   -17.706 1.587   1    81.91  ? 162 GLU A CA  1 
ATOM   3426 C  C   . GLU B 2 166 ? 0.948   -17.409 2.806   1    80.35  ? 162 GLU A C   1 
ATOM   3427 O  O   . GLU B 2 166 ? 1.151   -16.473 3.608   1    72.53  ? 162 GLU A O   1 
ATOM   3428 C  CB  . GLU B 2 166 ? 3.242   -17.135 1.721   1    92.53  ? 162 GLU A CB  1 
ATOM   3429 C  CG  . GLU B 2 166 ? 3.897   -16.856 0.372   1    97.71  ? 162 GLU A CG  1 
ATOM   3430 C  CD  . GLU B 2 166 ? 5.351   -16.433 0.402   1    90.34  ? 162 GLU A CD  1 
ATOM   3431 O  OE1 . GLU B 2 166 ? 5.632   -15.234 0.272   1    85.12  ? 162 GLU A OE1 1 
ATOM   3432 O  OE2 . GLU B 2 166 ? 6.213   -17.31  0.52    1    91.52  ? 162 GLU A OE2 1 
ATOM   3433 N  N   . VAL B 2 167 ? -0.158  -18.135 2.778   1    67.55  ? 163 VAL A N   1 
ATOM   3434 C  CA  . VAL B 2 167 ? -1.072  -18.219 3.885   1    57.42  ? 163 VAL A CA  1 
ATOM   3435 C  C   . VAL B 2 167 ? -1.092  -19.731 4.16    1    51.88  ? 163 VAL A C   1 
ATOM   3436 O  O   . VAL B 2 167 ? -0.629  -20.502 3.309   1    49.19  ? 163 VAL A O   1 
ATOM   3437 C  CB  . VAL B 2 167 ? -2.351  -17.618 3.264   1    52.78  ? 163 VAL A CB  1 
ATOM   3438 C  CG1 . VAL B 2 167 ? -3.137  -18.665 2.491   1    44.07  ? 163 VAL A CG1 1 
ATOM   3439 C  CG2 . VAL B 2 167 ? -3.203  -16.849 4.284   1    58.71  ? 163 VAL A CG2 1 
ATOM   3440 N  N   . VAL B 2 168 ? -1.469  -20.161 5.374   1    43.25  ? 164 VAL A N   1 
ATOM   3441 C  CA  . VAL B 2 168 ? -1.396  -21.572 5.755   1    39.5   ? 164 VAL A CA  1 
ATOM   3442 C  C   . VAL B 2 168 ? 0.036   -21.935 6.166   1    44.32  ? 164 VAL A C   1 
ATOM   3443 O  O   . VAL B 2 168 ? 0.972   -21.786 5.366   1    44.26  ? 164 VAL A O   1 
ATOM   3444 C  CB  . VAL B 2 168 ? -1.903  -22.581 4.697   1    38.52  ? 164 VAL A CB  1 
ATOM   3445 C  CG1 . VAL B 2 168 ? -2.152  -23.953 5.316   1    35.43  ? 164 VAL A CG1 1 
ATOM   3446 C  CG2 . VAL B 2 168 ? -3.158  -22.104 3.949   1    32.46  ? 164 VAL A CG2 1 
ATOM   3447 N  N   . THR B 2 169 ? 0.197   -22.414 7.419   1    40.77  ? 165 THR A N   1 
ATOM   3448 C  CA  . THR B 2 169 ? 1.414   -23.075 7.865   1    39.47  ? 165 THR A CA  1 
ATOM   3449 C  C   . THR B 2 169 ? 1.848   -24.095 6.806   1    42.13  ? 165 THR A C   1 
ATOM   3450 O  O   . THR B 2 169 ? 1.035   -24.875 6.273   1    37.44  ? 165 THR A O   1 
ATOM   3451 C  CB  . THR B 2 169 ? 1.176   -23.779 9.202   1    40.49  ? 165 THR A CB  1 
ATOM   3452 O  OG1 . THR B 2 169 ? 0.687   -22.788 10.095  1    41.67  ? 165 THR A OG1 1 
ATOM   3453 C  CG2 . THR B 2 169 ? 2.435   -24.384 9.803   1    37.25  ? 165 THR A CG2 1 
ATOM   3454 N  N   . LEU B 2 170 ? 3.168   -24.12  6.579   1    38.76  ? 166 LEU A N   1 
ATOM   3455 C  CA  . LEU B 2 170 ? 3.766   -24.699 5.394   1    39.15  ? 166 LEU A CA  1 
ATOM   3456 C  C   . LEU B 2 170 ? 3.422   -26.184 5.295   1    39.52  ? 166 LEU A C   1 
ATOM   3457 O  O   . LEU B 2 170 ? 3.129   -26.68  4.208   1    35.54  ? 166 LEU A O   1 
ATOM   3458 C  CB  . LEU B 2 170 ? 5.273   -24.489 5.513   1    41.25  ? 166 LEU A CB  1 
ATOM   3459 C  CG  . LEU B 2 170 ? 6.112   -25.039 4.354   1    42.18  ? 166 LEU A CG  1 
ATOM   3460 C  CD1 . LEU B 2 170 ? 5.81    -24.275 3.046   1    41.44  ? 166 LEU A CD1 1 
ATOM   3461 C  CD2 . LEU B 2 170 ? 7.592   -24.962 4.689   1    36.77  ? 166 LEU A CD2 1 
ATOM   3462 N  N   . TRP B 2 171 ? 3.513   -26.91  6.418   1    39.08  ? 167 TRP A N   1 
ATOM   3463 C  CA  . TRP B 2 171 ? 3.324   -28.348 6.295   1    36.92  ? 167 TRP A CA  1 
ATOM   3464 C  C   . TRP B 2 171 ? 1.933   -28.643 5.777   1    36.47  ? 167 TRP A C   1 
ATOM   3465 O  O   . TRP B 2 171 ? 1.724   -29.718 5.247   1    43.31  ? 167 TRP A O   1 
ATOM   3466 C  CB  . TRP B 2 171 ? 3.565   -29.085 7.61    1    35.14  ? 167 TRP A CB  1 
ATOM   3467 C  CG  . TRP B 2 171 ? 4.999   -29.067 8.059   1    35.04  ? 167 TRP A CG  1 
ATOM   3468 C  CD1 . TRP B 2 171 ? 6.09    -28.604 7.381   1    34.8   ? 167 TRP A CD1 1 
ATOM   3469 C  CD2 . TRP B 2 171 ? 5.478   -29.56  9.322   1    35.02  ? 167 TRP A CD2 1 
ATOM   3470 N  NE1 . TRP B 2 171 ? 7.217   -28.789 8.127   1    35.99  ? 167 TRP A NE1 1 
ATOM   3471 C  CE2 . TRP B 2 171 ? 6.878   -29.371 9.323   1    38.39  ? 167 TRP A CE2 1 
ATOM   3472 C  CE3 . TRP B 2 171 ? 4.867   -30.121 10.451  1    35.7   ? 167 TRP A CE3 1 
ATOM   3473 C  CZ2 . TRP B 2 171 ? 7.673   -29.749 10.413  1    40.15  ? 167 TRP A CZ2 1 
ATOM   3474 C  CZ3 . TRP B 2 171 ? 5.654   -30.494 11.525  1    36.55  ? 167 TRP A CZ3 1 
ATOM   3475 C  CH2 . TRP B 2 171 ? 7.042   -30.308 11.506  1    37.88  ? 167 TRP A CH2 1 
ATOM   3476 N  N   . TYR B 2 172 ? 1.019   -27.668 5.904   1    34     ? 168 TYR A N   1 
ATOM   3477 C  CA  . TYR B 2 172 ? -0.403  -27.897 5.682   1    33.06  ? 168 TYR A CA  1 
ATOM   3478 C  C   . TYR B 2 172 ? -0.88   -27.148 4.43    1    33.09  ? 168 TYR A C   1 
ATOM   3479 O  O   . TYR B 2 172 ? -2.067  -27.142 4.112   1    34.85  ? 168 TYR A O   1 
ATOM   3480 C  CB  . TYR B 2 172 ? -1.175  -27.634 6.986   1    28.15  ? 168 TYR A CB  1 
ATOM   3481 C  CG  . TYR B 2 172 ? -0.696  -28.474 8.16    1    30.31  ? 168 TYR A CG  1 
ATOM   3482 C  CD1 . TYR B 2 172 ? -1.213  -29.755 8.394   1    31.11  ? 168 TYR A CD1 1 
ATOM   3483 C  CD2 . TYR B 2 172 ? 0.299   -28.008 9.031   1    32.36  ? 168 TYR A CD2 1 
ATOM   3484 C  CE1 . TYR B 2 172 ? -0.78   -30.543 9.461   1    30.08  ? 168 TYR A CE1 1 
ATOM   3485 C  CE2 . TYR B 2 172 ? 0.745   -28.785 10.095  1    32.39  ? 168 TYR A CE2 1 
ATOM   3486 C  CZ  . TYR B 2 172 ? 0.206   -30.052 10.312  1    33.4   ? 168 TYR A CZ  1 
ATOM   3487 O  OH  . TYR B 2 172 ? 0.681   -30.789 11.361  1    33.15  ? 168 TYR A OH  1 
ATOM   3488 N  N   . ARG B 2 173 ? 0.055   -26.54  3.698   1    34.04  ? 169 ARG A N   1 
ATOM   3489 C  CA  . ARG B 2 173 ? -0.252  -25.645 2.595   1    35.39  ? 169 ARG A CA  1 
ATOM   3490 C  C   . ARG B 2 173 ? -0.454  -26.41  1.282   1    37.08  ? 169 ARG A C   1 
ATOM   3491 O  O   . ARG B 2 173 ? 0.395   -27.193 0.871   1    41.95  ? 169 ARG A O   1 
ATOM   3492 C  CB  . ARG B 2 173 ? 0.917   -24.671 2.462   1    35.33  ? 169 ARG A CB  1 
ATOM   3493 C  CG  . ARG B 2 173 ? 0.594   -23.521 1.518   1    35.45  ? 169 ARG A CG  1 
ATOM   3494 C  CD  . ARG B 2 173 ? 1.678   -22.482 1.49    1    31.81  ? 169 ARG A CD  1 
ATOM   3495 N  NE  . ARG B 2 173 ? 2.046   -22.042 2.837   1    33.6   ? 169 ARG A NE  1 
ATOM   3496 C  CZ  . ARG B 2 173 ? 3.138   -21.304 3.073   1    38.31  ? 169 ARG A CZ  1 
ATOM   3497 N  NH1 . ARG B 2 173 ? 3.971   -20.955 2.09    1    36.64  ? 169 ARG A NH1 1 
ATOM   3498 N  NH2 . ARG B 2 173 ? 3.423   -20.971 4.31    1    37.41  ? 169 ARG A NH2 1 
ATOM   3499 N  N   . ALA B 2 174 ? -1.564  -26.112 0.6     1    36.09  ? 170 ALA A N   1 
ATOM   3500 C  CA  . ALA B 2 174 ? -1.963  -26.742 -0.649  1    39.12  ? 170 ALA A CA  1 
ATOM   3501 C  C   . ALA B 2 174 ? -0.966  -26.43  -1.763  1    39.49  ? 170 ALA A C   1 
ATOM   3502 O  O   . ALA B 2 174 ? -0.26   -25.434 -1.715  1    41.19  ? 170 ALA A O   1 
ATOM   3503 C  CB  . ALA B 2 174 ? -3.36   -26.283 -1.029  1    38.38  ? 170 ALA A CB  1 
ATOM   3504 N  N   . PRO B 2 175 ? -0.85   -27.292 -2.794  1    39.7   ? 171 PRO A N   1 
ATOM   3505 C  CA  . PRO B 2 175 ? 0.076   -27.045 -3.904  1    38.09  ? 171 PRO A CA  1 
ATOM   3506 C  C   . PRO B 2 175 ? -0.192  -25.779 -4.716  1    40.16  ? 171 PRO A C   1 
ATOM   3507 O  O   . PRO B 2 175 ? 0.763   -25.145 -5.199  1    41.39  ? 171 PRO A O   1 
ATOM   3508 C  CB  . PRO B 2 175 ? -0.04   -28.322 -4.751  1    36.43  ? 171 PRO A CB  1 
ATOM   3509 C  CG  . PRO B 2 175 ? -1.421  -28.806 -4.414  1    37.22  ? 171 PRO A CG  1 
ATOM   3510 C  CD  . PRO B 2 175 ? -1.544  -28.58  -2.905  1    35.7   ? 171 PRO A CD  1 
ATOM   3511 N  N   . GLU B 2 176 ? -1.478  -25.427 -4.869  1    35.2   ? 172 GLU A N   1 
ATOM   3512 C  CA  . GLU B 2 176 ? -1.829  -24.273 -5.675  1    35     ? 172 GLU A CA  1 
ATOM   3513 C  C   . GLU B 2 176 ? -1.239  -23.009 -5.051  1    37.67  ? 172 GLU A C   1 
ATOM   3514 O  O   . GLU B 2 176 ? -0.851  -22.102 -5.788  1    39.35  ? 172 GLU A O   1 
ATOM   3515 C  CB  . GLU B 2 176 ? -3.308  -24.213 -6.061  1    38.01  ? 172 GLU A CB  1 
ATOM   3516 C  CG  . GLU B 2 176 ? -4.319  -24.192 -4.912  1    36.97  ? 172 GLU A CG  1 
ATOM   3517 C  CD  . GLU B 2 176 ? -4.781  -25.517 -4.286  1    38.86  ? 172 GLU A CD  1 
ATOM   3518 O  OE1 . GLU B 2 176 ? -5.916  -25.563 -3.724  1    36.65  ? 172 GLU A OE1 1 
ATOM   3519 O  OE2 . GLU B 2 176 ? -4.014  -26.505 -4.32   1    37.14  ? 172 GLU A OE2 1 
ATOM   3520 N  N   . ILE B 2 177 ? -1.118  -22.979 -3.705  1    35.18  ? 173 ILE A N   1 
ATOM   3521 C  CA  . ILE B 2 177 ? -0.557  -21.827 -3.014  1    34.69  ? 173 ILE A CA  1 
ATOM   3522 C  C   . ILE B 2 177 ? 0.954   -21.818 -3.218  1    37.72  ? 173 ILE A C   1 
ATOM   3523 O  O   . ILE B 2 177 ? 1.553   -20.788 -3.522  1    40.49  ? 173 ILE A O   1 
ATOM   3524 C  CB  . ILE B 2 177 ? -0.954  -21.827 -1.525  1    35.71  ? 173 ILE A CB  1 
ATOM   3525 C  CG1 . ILE B 2 177 ? -2.49   -21.781 -1.331  1    35.37  ? 173 ILE A CG1 1 
ATOM   3526 C  CG2 . ILE B 2 177 ? -0.27   -20.697 -0.755  1    31.05  ? 173 ILE A CG2 1 
ATOM   3527 C  CD1 . ILE B 2 177 ? -2.948  -21.946 0.113   1    32.6   ? 173 ILE A CD1 1 
ATOM   3528 N  N   . LEU B 2 178 ? 1.571   -22.991 -3.092  1    37.76  ? 174 LEU A N   1 
ATOM   3529 C  CA  . LEU B 2 178 ? 3.012   -23.127 -3.26   1    38.58  ? 174 LEU A CA  1 
ATOM   3530 C  C   . LEU B 2 178 ? 3.441   -22.765 -4.679  1    41.16  ? 174 LEU A C   1 
ATOM   3531 O  O   . LEU B 2 178 ? 4.556   -22.265 -4.872  1    44.36  ? 174 LEU A O   1 
ATOM   3532 C  CB  . LEU B 2 178 ? 3.404   -24.559 -2.907  1    36.25  ? 174 LEU A CB  1 
ATOM   3533 C  CG  . LEU B 2 178 ? 3.426   -24.872 -1.409  1    34.11  ? 174 LEU A CG  1 
ATOM   3534 C  CD1 . LEU B 2 178 ? 3.32    -26.375 -1.217  1    32.85  ? 174 LEU A CD1 1 
ATOM   3535 C  CD2 . LEU B 2 178 ? 4.709   -24.296 -0.801  1    32.74  ? 174 LEU A CD2 1 
ATOM   3536 N  N   . LEU B 2 179 ? 2.549   -22.998 -5.661  1    38.41  ? 175 LEU A N   1 
ATOM   3537 C  CA  . LEU B 2 179 ? 2.858   -22.715 -7.057  1    37.83  ? 175 LEU A CA  1 
ATOM   3538 C  C   . LEU B 2 179 ? 2.503   -21.273 -7.441  1    40.44  ? 175 LEU A C   1 
ATOM   3539 O  O   . LEU B 2 179 ? 2.567   -20.91  -8.618  1    43.57  ? 175 LEU A O   1 
ATOM   3540 C  CB  . LEU B 2 179 ? 2.126   -23.723 -7.941  1    34.38  ? 175 LEU A CB  1 
ATOM   3541 C  CG  . LEU B 2 179 ? 2.63    -25.164 -7.899  1    33.34  ? 175 LEU A CG  1 
ATOM   3542 C  CD1 . LEU B 2 179 ? 1.723   -26.036 -8.754  1    34.73  ? 175 LEU A CD1 1 
ATOM   3543 C  CD2 . LEU B 2 179 ? 4.062   -25.284 -8.34   1    31.94  ? 175 LEU A CD2 1 
ATOM   3544 N  N   . GLY B 2 180 ? 2.124   -20.442 -6.459  1    41.17  ? 176 GLY A N   1 
ATOM   3545 C  CA  . GLY B 2 180 ? 1.895   -19.027 -6.707  1    43.39  ? 176 GLY A CA  1 
ATOM   3546 C  C   . GLY B 2 180 ? 0.649   -18.766 -7.561  1    46.31  ? 176 GLY A C   1 
ATOM   3547 O  O   . GLY B 2 180 ? 0.59    -17.762 -8.27   1    48.25  ? 176 GLY A O   1 
ATOM   3548 N  N   . CYS B 2 181 ? -0.351  -19.658 -7.479  1    45.26  ? 177 CYS A N   1 
ATOM   3549 C  CA  . CYS B 2 181 ? -1.561  -19.506 -8.283  1    51.14  ? 177 CYS A CA  1 
ATOM   3550 C  C   . CYS B 2 181 ? -2.227  -18.176 -7.923  1    47.6   ? 177 CYS A C   1 
ATOM   3551 O  O   . CYS B 2 181 ? -2.255  -17.791 -6.752  1    48.97  ? 177 CYS A O   1 
ATOM   3552 C  CB  . CYS B 2 181 ? -2.467  -20.746 -8.219  1    57.78  ? 177 CYS A CB  1 
ATOM   3553 S  SG  . CYS B 2 181 ? -2.072  -22.1   -9.391  1    69.16  ? 177 CYS A SG  1 
ATOM   3554 N  N   . LYS B 2 182 ? -2.739  -17.48  -8.944  1    44.08  ? 178 LYS A N   1 
ATOM   3555 C  CA  . LYS B 2 182 ? -3.429  -16.211 -8.762  1    46.68  ? 178 LYS A CA  1 
ATOM   3556 C  C   . LYS B 2 182 ? -4.651  -16.332 -7.84   1    43.38  ? 178 LYS A C   1 
ATOM   3557 O  O   . LYS B 2 182 ? -5.025  -15.355 -7.186  1    43.25  ? 178 LYS A O   1 
ATOM   3558 C  CB  . LYS B 2 182 ? -3.763  -15.649 -10.147 1    51.12  ? 178 LYS A CB  1 
ATOM   3559 C  CG  . LYS B 2 182 ? -4.934  -14.667 -10.187 1    62.51  ? 178 LYS A CG  1 
ATOM   3560 C  CD  . LYS B 2 182 ? -5.177  -14.079 -11.584 1    67.76  ? 178 LYS A CD  1 
ATOM   3561 C  CE  . LYS B 2 182 ? -5.476  -12.604 -11.49  1    79.82  ? 178 LYS A CE  1 
ATOM   3562 N  NZ  . LYS B 2 182 ? -6.128  -12.005 -12.657 1    83.33  ? 178 LYS A NZ  1 
ATOM   3563 N  N   . TYR B 2 183 ? -5.297  -17.497 -7.857  1    40.07  ? 179 TYR A N   1 
ATOM   3564 C  CA  . TYR B 2 183 ? -6.554  -17.678 -7.092  1    39.51  ? 179 TYR A CA  1 
ATOM   3565 C  C   . TYR B 2 183 ? -6.566  -18.986 -6.338  1    37.88  ? 179 TYR A C   1 
ATOM   3566 O  O   . TYR B 2 183 ? -6.143  -20.007 -6.885  1    38.02  ? 179 TYR A O   1 
ATOM   3567 C  CB  . TYR B 2 183 ? -7.741  -17.718 -8.055  1    39.43  ? 179 TYR A CB  1 
ATOM   3568 C  CG  . TYR B 2 183 ? -8.039  -16.471 -8.868  1    38.73  ? 179 TYR A CG  1 
ATOM   3569 C  CD1 . TYR B 2 183 ? -8.204  -15.235 -8.26   1    38.84  ? 179 TYR A CD1 1 
ATOM   3570 C  CD2 . TYR B 2 183 ? -8.18   -16.543 -10.246 1    36.88  ? 179 TYR A CD2 1 
ATOM   3571 C  CE1 . TYR B 2 183 ? -8.485  -14.103 -9.003  1    41.33  ? 179 TYR A CE1 1 
ATOM   3572 C  CE2 . TYR B 2 183 ? -8.465  -15.419 -10.999 1    39.29  ? 179 TYR A CE2 1 
ATOM   3573 C  CZ  . TYR B 2 183 ? -8.617  -14.196 -10.375 1    42.73  ? 179 TYR A CZ  1 
ATOM   3574 O  OH  . TYR B 2 183 ? -8.893  -13.088 -11.118 1    46.27  ? 179 TYR A OH  1 
ATOM   3575 N  N   . TYR B 2 184 ? -7.058  -18.953 -5.104  1    37.44  ? 180 TYR A N   1 
ATOM   3576 C  CA  . TYR B 2 184 ? -7.209  -20.185 -4.289  1    38.24  ? 180 TYR A CA  1 
ATOM   3577 C  C   . TYR B 2 184 ? -8.594  -20.135 -3.653  1    40.66  ? 180 TYR A C   1 
ATOM   3578 O  O   . TYR B 2 184 ? -9.163  -19.042 -3.541  1    36.84  ? 180 TYR A O   1 
ATOM   3579 C  CB  . TYR B 2 184 ? -6.082  -20.372 -3.269  1    38.88  ? 180 TYR A CB  1 
ATOM   3580 C  CG  . TYR B 2 184 ? -5.85   -19.291 -2.224  1    42.24  ? 180 TYR A CG  1 
ATOM   3581 C  CD1 . TYR B 2 184 ? -6.685  -19.157 -1.124  1    37.53  ? 180 TYR A CD1 1 
ATOM   3582 C  CD2 . TYR B 2 184 ? -4.762  -18.437 -2.319  1    39.91  ? 180 TYR A CD2 1 
ATOM   3583 C  CE1 . TYR B 2 184 ? -6.463  -18.183 -0.168  1    41.55  ? 180 TYR A CE1 1 
ATOM   3584 C  CE2 . TYR B 2 184 ? -4.529  -17.46  -1.37   1    41.46  ? 180 TYR A CE2 1 
ATOM   3585 C  CZ  . TYR B 2 184 ? -5.381  -17.333 -0.291  1    42.81  ? 180 TYR A CZ  1 
ATOM   3586 O  OH  . TYR B 2 184 ? -5.145  -16.373 0.643   1    45.81  ? 180 TYR A OH  1 
ATOM   3587 N  N   . SER B 2 185 ? -9.115  -21.286 -3.239  1    35.42  ? 181 SER A N   1 
ATOM   3588 C  CA  . SER B 2 185 ? -10.499 -21.306 -2.712  1    38.42  ? 181 SER A CA  1 
ATOM   3589 C  C   . SER B 2 185 ? -10.661 -22.26  -1.531  1    37.39  ? 181 SER A C   1 
ATOM   3590 O  O   . SER B 2 185 ? -9.71   -22.418 -0.766  1    38.87  ? 181 SER A O   1 
ATOM   3591 C  CB  . SER B 2 185 ? -11.492 -21.64  -3.796  1    39.01  ? 181 SER A CB  1 
ATOM   3592 O  OG  . SER B 2 185 ? -12.81  -21.276 -3.422  1    42.02  ? 181 SER A OG  1 
ATOM   3593 N  N   . THR B 2 186 ? -11.839 -22.855 -1.419  1    34.32  ? 182 THR A N   1 
ATOM   3594 C  CA  . THR B 2 186 ? -12.19  -23.722 -0.286  1    35.89  ? 182 THR A CA  1 
ATOM   3595 C  C   . THR B 2 186 ? -11.378 -24.982 -0.298  1    36.86  ? 182 THR A C   1 
ATOM   3596 O  O   . THR B 2 186 ? -11.33  -25.658 0.735   1    39.01  ? 182 THR A O   1 
ATOM   3597 C  CB  . THR B 2 186 ? -13.679 -23.984 -0.487  1    37.69  ? 182 THR A CB  1 
ATOM   3598 O  OG1 . THR B 2 186 ? -13.837 -24.424 -1.83   1    34.48  ? 182 THR A OG1 1 
ATOM   3599 C  CG2 . THR B 2 186 ? -14.518 -22.741 -0.261  1    35.29  ? 182 THR A CG2 1 
ATOM   3600 N  N   . ALA B 2 187 ? -10.738 -25.276 -1.419  1    36.84  ? 183 ALA A N   1 
ATOM   3601 C  CA  . ALA B 2 187 ? -9.99   -26.514 -1.58   1    36.75  ? 183 ALA A CA  1 
ATOM   3602 C  C   . ALA B 2 187 ? -8.693  -26.512 -0.762  1    38.37  ? 183 ALA A C   1 
ATOM   3603 O  O   . ALA B 2 187 ? -8.185  -27.595 -0.438  1    39.74  ? 183 ALA A O   1 
ATOM   3604 C  CB  . ALA B 2 187 ? -9.748  -26.777 -3.046  1    33.43  ? 183 ALA A CB  1 
ATOM   3605 N  N   . VAL B 2 188 ? -8.174  -25.307 -0.448  1    33.49  ? 184 VAL A N   1 
ATOM   3606 C  CA  . VAL B 2 188 ? -6.97   -25.159 0.352   1    35.88  ? 184 VAL A CA  1 
ATOM   3607 C  C   . VAL B 2 188 ? -7.249  -25.572 1.806   1    37.52  ? 184 VAL A C   1 
ATOM   3608 O  O   . VAL B 2 188 ? -6.345  -26.031 2.493   1    43.32  ? 184 VAL A O   1 
ATOM   3609 C  CB  . VAL B 2 188 ? -6.308  -23.764 0.248   1    35.87  ? 184 VAL A CB  1 
ATOM   3610 C  CG1 . VAL B 2 188 ? -6.365  -23.215 -1.166  1    34.78  ? 184 VAL A CG1 1 
ATOM   3611 C  CG2 . VAL B 2 188 ? -6.908  -22.772 1.224   1    31.04  ? 184 VAL A CG2 1 
ATOM   3612 N  N   . ASP B 2 189 ? -8.503  -25.46  2.276   1    37.54  ? 185 ASP A N   1 
ATOM   3613 C  CA  . ASP B 2 189 ? -8.869  -25.899 3.62    1    36.05  ? 185 ASP A CA  1 
ATOM   3614 C  C   . ASP B 2 189 ? -9.028  -27.414 3.631   1    35.4   ? 185 ASP A C   1 
ATOM   3615 O  O   . ASP B 2 189 ? -8.681  -28.06  4.619   1    39.06  ? 185 ASP A O   1 
ATOM   3616 C  CB  . ASP B 2 189 ? -10.054 -25.146 4.22    1    34.41  ? 185 ASP A CB  1 
ATOM   3617 C  CG  . ASP B 2 189 ? -9.823  -23.698 4.634   1    38.97  ? 185 ASP A CG  1 
ATOM   3618 O  OD1 . ASP B 2 189 ? -8.642  -23.334 4.897   1    39.86  ? 185 ASP A OD1 1 
ATOM   3619 O  OD2 . ASP B 2 189 ? -10.829 -22.916 4.655   1    38.03  ? 185 ASP A OD2 1 
ATOM   3620 N  N   . ILE B 2 190 ? -9.567  -27.974 2.542   1    33.03  ? 186 ILE A N   1 
ATOM   3621 C  CA  . ILE B 2 190 ? -9.656  -29.42  2.389   1    32.09  ? 186 ILE A CA  1 
ATOM   3622 C  C   . ILE B 2 190 ? -8.263  -30.052 2.368   1    35.19  ? 186 ILE A C   1 
ATOM   3623 O  O   . ILE B 2 190 ? -8.025  -31.087 3.021   1    33.03  ? 186 ILE A O   1 
ATOM   3624 C  CB  . ILE B 2 190 ? -10.486 -29.788 1.149   1    32.47  ? 186 ILE A CB  1 
ATOM   3625 C  CG1 . ILE B 2 190 ? -11.979 -29.44  1.379   1    29.48  ? 186 ILE A CG1 1 
ATOM   3626 C  CG2 . ILE B 2 190 ? -10.288 -31.256 0.776   1    28.74  ? 186 ILE A CG2 1 
ATOM   3627 C  CD1 . ILE B 2 190 ? -12.59  -30.192 2.542   1    26.76  ? 186 ILE A CD1 1 
ATOM   3628 N  N   . TRP B 2 191 ? -7.332  -29.412 1.634   1    35.11  ? 187 TRP A N   1 
ATOM   3629 C  CA  . TRP B 2 191 ? -5.957  -29.909 1.606   1    36.61  ? 187 TRP A CA  1 
ATOM   3630 C  C   . TRP B 2 191 ? -5.419  -30.113 3.025   1    38     ? 187 TRP A C   1 
ATOM   3631 O  O   . TRP B 2 191 ? -4.928  -31.185 3.378   1    41.53  ? 187 TRP A O   1 
ATOM   3632 C  CB  . TRP B 2 191 ? -5.022  -29.017 0.777   1    34.07  ? 187 TRP A CB  1 
ATOM   3633 C  CG  . TRP B 2 191 ? -3.631  -29.596 0.698   1    35.29  ? 187 TRP A CG  1 
ATOM   3634 C  CD1 . TRP B 2 191 ? -2.628  -29.384 1.598   1    33.01  ? 187 TRP A CD1 1 
ATOM   3635 C  CD2 . TRP B 2 191 ? -3.079  -30.48  -0.308  1    31.19  ? 187 TRP A CD2 1 
ATOM   3636 N  NE1 . TRP B 2 191 ? -1.517  -30.096 1.242   1    32.66  ? 187 TRP A NE1 1 
ATOM   3637 C  CE2 . TRP B 2 191 ? -1.744  -30.742 0.065   1    30.13  ? 187 TRP A CE2 1 
ATOM   3638 C  CE3 . TRP B 2 191 ? -3.568  -31.062 -1.48   1    30.88  ? 187 TRP A CE3 1 
ATOM   3639 C  CZ2 . TRP B 2 191 ? -0.891  -31.548 -0.681  1    30.54  ? 187 TRP A CZ2 1 
ATOM   3640 C  CZ3 . TRP B 2 191 ? -2.723  -31.847 -2.239  1    33.09  ? 187 TRP A CZ3 1 
ATOM   3641 C  CH2 . TRP B 2 191 ? -1.395  -32.085 -1.847  1    32.68  ? 187 TRP A CH2 1 
ATOM   3642 N  N   . SER B 2 192 ? -5.541  -29.069 3.848   1    39.4   ? 188 SER A N   1 
ATOM   3643 C  CA  . SER B 2 192 ? -5.052  -29.073 5.217   1    35.1   ? 188 SER A CA  1 
ATOM   3644 C  C   . SER B 2 192 ? -5.666  -30.226 6.016   1    33.46  ? 188 SER A C   1 
ATOM   3645 O  O   . SER B 2 192 ? -4.96   -30.979 6.697   1    32.05  ? 188 SER A O   1 
ATOM   3646 C  CB  . SER B 2 192 ? -5.288  -27.732 5.844   1    33.81  ? 188 SER A CB  1 
ATOM   3647 O  OG  . SER B 2 192 ? -4.564  -26.745 5.128   1    38.73  ? 188 SER A OG  1 
ATOM   3648 N  N   . LEU B 2 193 ? -6.994  -30.367 5.9     1    34.09  ? 189 LEU A N   1 
ATOM   3649 C  CA  . LEU B 2 193 ? -7.722  -31.439 6.565   1    33.89  ? 189 LEU A CA  1 
ATOM   3650 C  C   . LEU B 2 193 ? -7.212  -32.811 6.113   1    33.2   ? 189 LEU A C   1 
ATOM   3651 O  O   . LEU B 2 193 ? -7.14   -33.733 6.918   1    32.92  ? 189 LEU A O   1 
ATOM   3652 C  CB  . LEU B 2 193 ? -9.208  -31.296 6.264   1    33.42  ? 189 LEU A CB  1 
ATOM   3653 C  CG  . LEU B 2 193 ? -10.022 -30.388 7.171   1    37.14  ? 189 LEU A CG  1 
ATOM   3654 C  CD1 . LEU B 2 193 ? -11.407 -31.028 7.253   1    38.22  ? 189 LEU A CD1 1 
ATOM   3655 C  CD2 . LEU B 2 193 ? -9.396  -30.275 8.562   1    41.09  ? 189 LEU A CD2 1 
ATOM   3656 N  N   . GLY B 2 194 ? -6.926  -32.958 4.813   1    32.97  ? 190 GLY A N   1 
ATOM   3657 C  CA  . GLY B 2 194 ? -6.267  -34.164 4.336   1    37.67  ? 190 GLY A CA  1 
ATOM   3658 C  C   . GLY B 2 194 ? -4.956  -34.432 5.085   1    38.52  ? 190 GLY A C   1 
ATOM   3659 O  O   . GLY B 2 194 ? -4.783  -35.513 5.666   1    38.99  ? 190 GLY A O   1 
ATOM   3660 N  N   . CYS B 2 195 ? -4.047  -33.443 5.095   1    34.95  ? 191 CYS A N   1 
ATOM   3661 C  CA  . CYS B 2 195 ? -2.775  -33.612 5.793   1    34.78  ? 191 CYS A CA  1 
ATOM   3662 C  C   . CYS B 2 195 ? -3.034  -34.031 7.248   1    37.06  ? 191 CYS A C   1 
ATOM   3663 O  O   . CYS B 2 195 ? -2.362  -34.922 7.767   1    36.3   ? 191 CYS A O   1 
ATOM   3664 C  CB  . CYS B 2 195 ? -1.918  -32.35  5.685   1    30.4   ? 191 CYS A CB  1 
ATOM   3665 S  SG  . CYS B 2 195 ? -1.517  -31.891 3.977   1    30.96  ? 191 CYS A SG  1 
ATOM   3666 N  N   . ILE B 2 196 ? -4.045  -33.412 7.892   1    33.76  ? 192 ILE A N   1 
ATOM   3667 C  CA  . ILE B 2 196 ? -4.406  -33.713 9.268   1    34.28  ? 192 ILE A CA  1 
ATOM   3668 C  C   . ILE B 2 196 ? -4.967  -35.131 9.422   1    38.51  ? 192 ILE A C   1 
ATOM   3669 O  O   . ILE B 2 196 ? -4.648  -35.803 10.401  1    42.07  ? 192 ILE A O   1 
ATOM   3670 C  CB  . ILE B 2 196 ? -5.367  -32.64  9.818   1    33.34  ? 192 ILE A CB  1 
ATOM   3671 C  CG1 . ILE B 2 196 ? -4.623  -31.303 9.855   1    32.34  ? 192 ILE A CG1 1 
ATOM   3672 C  CG2 . ILE B 2 196 ? -5.935  -33.027 11.195  1    29.11  ? 192 ILE A CG2 1 
ATOM   3673 C  CD1 . ILE B 2 196 ? -5.518  -30.122 10.085  1    29.72  ? 192 ILE A CD1 1 
ATOM   3674 N  N   . PHE B 2 197 ? -5.861  -35.566 8.516   1    37.69  ? 193 PHE A N   1 
ATOM   3675 C  CA  . PHE B 2 197 ? -6.363  -36.935 8.51    1    35.23  ? 193 PHE A CA  1 
ATOM   3676 C  C   . PHE B 2 197 ? -5.187  -37.909 8.566   1    35.57  ? 193 PHE A C   1 
ATOM   3677 O  O   . PHE B 2 197 ? -5.145  -38.754 9.442   1    39.02  ? 193 PHE A O   1 
ATOM   3678 C  CB  . PHE B 2 197 ? -7.241  -37.165 7.274   1    35.28  ? 193 PHE A CB  1 
ATOM   3679 C  CG  . PHE B 2 197 ? -7.872  -38.538 7.09    1    34.62  ? 193 PHE A CG  1 
ATOM   3680 C  CD1 . PHE B 2 197 ? -7.951  -39.453 8.143   1    35.47  ? 193 PHE A CD1 1 
ATOM   3681 C  CD2 . PHE B 2 197 ? -8.396  -38.911 5.846   1    35.32  ? 193 PHE A CD2 1 
ATOM   3682 C  CE1 . PHE B 2 197 ? -8.563  -40.709 7.973   1    37.27  ? 193 PHE A CE1 1 
ATOM   3683 C  CE2 . PHE B 2 197 ? -8.999  -40.158 5.662   1    36.4   ? 193 PHE A CE2 1 
ATOM   3684 C  CZ  . PHE B 2 197 ? -9.085  -41.065 6.728   1    39.46  ? 193 PHE A CZ  1 
ATOM   3685 N  N   . ALA B 2 198 ? -4.233  -37.778 7.64    1    34     ? 194 ALA A N   1 
ATOM   3686 C  CA  . ALA B 2 198 ? -3.08   -38.665 7.582   1    35.9   ? 194 ALA A CA  1 
ATOM   3687 C  C   . ALA B 2 198 ? -2.301  -38.623 8.89    1    38.04  ? 194 ALA A C   1 
ATOM   3688 O  O   . ALA B 2 198 ? -1.826  -39.659 9.356   1    39.06  ? 194 ALA A O   1 
ATOM   3689 C  CB  . ALA B 2 198 ? -2.189  -38.308 6.406   1    31.81  ? 194 ALA A CB  1 
ATOM   3690 N  N   . GLU B 2 199 ? -2.2    -37.416 9.473   1    39.36  ? 195 GLU A N   1 
ATOM   3691 C  CA  . GLU B 2 199 ? -1.394  -37.173 10.663  1    39.94  ? 195 GLU A CA  1 
ATOM   3692 C  C   . GLU B 2 199 ? -2.028  -37.787 11.918  1    41.71  ? 195 GLU A C   1 
ATOM   3693 O  O   . GLU B 2 199 ? -1.326  -38.223 12.82   1    49.57  ? 195 GLU A O   1 
ATOM   3694 C  CB  . GLU B 2 199 ? -1.099  -35.68  10.809  1    36.76  ? 195 GLU A CB  1 
ATOM   3695 C  CG  . GLU B 2 199 ? -0.189  -35.381 11.995  1    35.49  ? 195 GLU A CG  1 
ATOM   3696 C  CD  . GLU B 2 199 ? 0.279   -33.943 12.077  1    36.1   ? 195 GLU A CD  1 
ATOM   3697 O  OE1 . GLU B 2 199 ? 0.128   -33.249 11.05   1    33.12  ? 195 GLU A OE1 1 
ATOM   3698 O  OE2 . GLU B 2 199 ? 0.784   -33.538 13.16   1    38.87  ? 195 GLU A OE2 1 
ATOM   3699 N  N   . MET B 2 200 ? -3.355  -37.835 11.987  1    41.34  ? 196 MET A N   1 
ATOM   3700 C  CA  . MET B 2 200 ? -4.031  -38.517 13.08   1    42.92  ? 196 MET A CA  1 
ATOM   3701 C  C   . MET B 2 200 ? -3.772  -40.019 13.046  1    41.52  ? 196 MET A C   1 
ATOM   3702 O  O   . MET B 2 200 ? -3.911  -40.661 14.071  1    43.18  ? 196 MET A O   1 
ATOM   3703 C  CB  . MET B 2 200 ? -5.55   -38.293 13.02   1    43.24  ? 196 MET A CB  1 
ATOM   3704 C  CG  . MET B 2 200 ? -5.935  -36.873 13.402  1    39.77  ? 196 MET A CG  1 
ATOM   3705 S  SD  . MET B 2 200 ? -7.7    -36.685 13.69   1    35.67  ? 196 MET A SD  1 
ATOM   3706 C  CE  . MET B 2 200 ? -8.393  -36.503 12.041  1    33.9   ? 196 MET A CE  1 
ATOM   3707 N  N   . VAL B 2 201 ? -3.464  -40.578 11.866  1    40.78  ? 197 VAL A N   1 
ATOM   3708 C  CA  . VAL B 2 201 ? -3.313  -42.018 11.717  1    43.86  ? 197 VAL A CA  1 
ATOM   3709 C  C   . VAL B 2 201 ? -1.891  -42.412 12.132  1    47.88  ? 197 VAL A C   1 
ATOM   3710 O  O   . VAL B 2 201 ? -1.707  -43.412 12.822  1    50.12  ? 197 VAL A O   1 
ATOM   3711 C  CB  . VAL B 2 201 ? -3.624  -42.553 10.302  1    39.11  ? 197 VAL A CB  1 
ATOM   3712 C  CG1 . VAL B 2 201 ? -3.136  -43.986 10.159  1    39.33  ? 197 VAL A CG1 1 
ATOM   3713 C  CG2 . VAL B 2 201 ? -5.092  -42.46  9.918   1    34.39  ? 197 VAL A CG2 1 
ATOM   3714 N  N   . THR B 2 202 ? -0.9    -41.631 11.674  1    47.89  ? 198 THR A N   1 
ATOM   3715 C  CA  . THR B 2 202 ? 0.526   -41.89  11.893  1    50.24  ? 198 THR A CA  1 
ATOM   3716 C  C   . THR B 2 202 ? 1.072   -41.116 13.099  1    52.13  ? 198 THR A C   1 
ATOM   3717 O  O   . THR B 2 202 ? 2.145   -41.445 13.586  1    57.2   ? 198 THR A O   1 
ATOM   3718 C  CB  . THR B 2 202 ? 1.367   -41.502 10.676  1    47.36  ? 198 THR A CB  1 
ATOM   3719 O  OG1 . THR B 2 202 ? 1.277   -40.075 10.678  1    54.94  ? 198 THR A OG1 1 
ATOM   3720 C  CG2 . THR B 2 202 ? 0.853   -42.068 9.37    1    43.78  ? 198 THR A CG2 1 
ATOM   3721 N  N   . ARG B 2 203 ? 0.399   -40.043 13.537  1    50.48  ? 199 ARG A N   1 
ATOM   3722 C  CA  . ARG B 2 203 ? 0.946   -39.146 14.547  1    50.97  ? 199 ARG A CA  1 
ATOM   3723 C  C   . ARG B 2 203 ? 2.254   -38.496 14.093  1    50.44  ? 199 ARG A C   1 
ATOM   3724 O  O   . ARG B 2 203 ? 3.039   -38.086 14.936  1    53.34  ? 199 ARG A O   1 
ATOM   3725 C  CB  . ARG B 2 203 ? 1.161   -39.846 15.894  1    59.06  ? 199 ARG A CB  1 
ATOM   3726 C  CG  . ARG B 2 203 ? -0.097  -39.904 16.752  1    65.42  ? 199 ARG A CG  1 
ATOM   3727 C  CD  . ARG B 2 203 ? -0.179  -41.227 17.479  1    65.47  ? 199 ARG A CD  1 
ATOM   3728 N  NE  . ARG B 2 203 ? -0.228  -42.336 16.52   1    65.98  ? 199 ARG A NE  1 
ATOM   3729 C  CZ  . ARG B 2 203 ? 0.633   -43.346 16.503  1    63.71  ? 199 ARG A CZ  1 
ATOM   3730 N  NH1 . ARG B 2 203 ? 1.516   -43.456 17.481  1    61.71  ? 199 ARG A NH1 1 
ATOM   3731 N  NH2 . ARG B 2 203 ? 0.585   -44.24  15.524  1    60.35  ? 199 ARG A NH2 1 
ATOM   3732 N  N   . ARG B 2 204 ? 2.466   -38.358 12.776  1    48.47  ? 200 ARG A N   1 
ATOM   3733 C  CA  . ARG B 2 204 ? 3.533   -37.522 12.245  1    48.19  ? 200 ARG A CA  1 
ATOM   3734 C  C   . ARG B 2 204 ? 3.033   -36.768 11.01   1    44.91  ? 200 ARG A C   1 
ATOM   3735 O  O   . ARG B 2 204 ? 2.163   -37.261 10.299  1    50.32  ? 200 ARG A O   1 
ATOM   3736 C  CB  . ARG B 2 204 ? 4.746   -38.399 11.929  1    53.56  ? 200 ARG A CB  1 
ATOM   3737 C  CG  . ARG B 2 204 ? 4.548   -39.127 10.611  1    55.73  ? 200 ARG A CG  1 
ATOM   3738 C  CD  . ARG B 2 204 ? 5.586   -40.197 10.347  1    65.61  ? 200 ARG A CD  1 
ATOM   3739 N  NE  . ARG B 2 204 ? 5.395   -40.694 8.981   1    70.67  ? 200 ARG A NE  1 
ATOM   3740 C  CZ  . ARG B 2 204 ? 6.33    -41.344 8.293   1    73.31  ? 200 ARG A CZ  1 
ATOM   3741 N  NH1 . ARG B 2 204 ? 7.527   -41.484 8.832   1    75.32  ? 200 ARG A NH1 1 
ATOM   3742 N  NH2 . ARG B 2 204 ? 6.08    -41.832 7.079   1    70.79  ? 200 ARG A NH2 1 
ATOM   3743 N  N   . ALA B 2 205 ? 3.583   -35.574 10.759  1    40.79  ? 201 ALA A N   1 
ATOM   3744 C  CA  . ALA B 2 205 ? 3.199   -34.758 9.615   1    38.88  ? 201 ALA A CA  1 
ATOM   3745 C  C   . ALA B 2 205 ? 3.438   -35.506 8.301   1    42.01  ? 201 ALA A C   1 
ATOM   3746 O  O   . ALA B 2 205 ? 4.427   -36.222 8.164   1    47.58  ? 201 ALA A O   1 
ATOM   3747 C  CB  . ALA B 2 205 ? 3.971   -33.469 9.644   1    35.29  ? 201 ALA A CB  1 
ATOM   3748 N  N   . LEU B 2 206 ? 2.529   -35.328 7.342   1    38.9   ? 202 LEU A N   1 
ATOM   3749 C  CA  . LEU B 2 206 ? 2.599   -36.016 6.066   1    38.81  ? 202 LEU A CA  1 
ATOM   3750 C  C   . LEU B 2 206 ? 3.616   -35.364 5.138   1    40.07  ? 202 LEU A C   1 
ATOM   3751 O  O   . LEU B 2 206 ? 4.324   -36.053 4.421   1    46.54  ? 202 LEU A O   1 
ATOM   3752 C  CB  . LEU B 2 206 ? 1.208   -36.031 5.431   1    34.66  ? 202 LEU A CB  1 
ATOM   3753 C  CG  . LEU B 2 206 ? 1.088   -36.781 4.098   1    33.52  ? 202 LEU A CG  1 
ATOM   3754 C  CD1 . LEU B 2 206 ? 1.376   -38.288 4.228   1    32.75  ? 202 LEU A CD1 1 
ATOM   3755 C  CD2 . LEU B 2 206 ? -0.299  -36.562 3.574   1    31.84  ? 202 LEU A CD2 1 
ATOM   3756 N  N   . PHE B 2 207 ? 3.668   -34.033 5.114   1    40.24  ? 203 PHE A N   1 
ATOM   3757 C  CA  . PHE B 2 207 ? 4.656   -33.355 4.283   1    39.71  ? 203 PHE A CA  1 
ATOM   3758 C  C   . PHE B 2 207 ? 5.451   -32.37  5.13    1    40.82  ? 203 PHE A C   1 
ATOM   3759 O  O   . PHE B 2 207 ? 5.124   -31.185 5.165   1    47.63  ? 203 PHE A O   1 
ATOM   3760 C  CB  . PHE B 2 207 ? 3.895   -32.632 3.168   1    37.25  ? 203 PHE A CB  1 
ATOM   3761 C  CG  . PHE B 2 207 ? 3.032   -33.549 2.319   1    33.87  ? 203 PHE A CG  1 
ATOM   3762 C  CD1 . PHE B 2 207 ? 3.591   -34.628 1.641   1    33.66  ? 203 PHE A CD1 1 
ATOM   3763 C  CD2 . PHE B 2 207 ? 1.666   -33.328 2.207   1    33.18  ? 203 PHE A CD2 1 
ATOM   3764 C  CE1 . PHE B 2 207 ? 2.804   -35.451 0.852   1    33.73  ? 203 PHE A CE1 1 
ATOM   3765 C  CE2 . PHE B 2 207 ? 0.872   -34.162 1.422   1    31.94  ? 203 PHE A CE2 1 
ATOM   3766 C  CZ  . PHE B 2 207 ? 1.445   -35.228 0.743   1    31.83  ? 203 PHE A CZ  1 
ATOM   3767 N  N   . PRO B 2 208 ? 6.485   -32.81  5.883   1    41.77  ? 204 PRO A N   1 
ATOM   3768 C  CA  . PRO B 2 208 ? 7.174   -31.893 6.799   1    39.64  ? 204 PRO A CA  1 
ATOM   3769 C  C   . PRO B 2 208 ? 8.342   -31.171 6.131   1    41.68  ? 204 PRO A C   1 
ATOM   3770 O  O   . PRO B 2 208 ? 9.501   -31.483 6.41    1    41.66  ? 204 PRO A O   1 
ATOM   3771 C  CB  . PRO B 2 208 ? 7.624   -32.878 7.898   1    36.26  ? 204 PRO A CB  1 
ATOM   3772 C  CG  . PRO B 2 208 ? 7.964   -34.15  7.136   1    34.54  ? 204 PRO A CG  1 
ATOM   3773 C  CD  . PRO B 2 208 ? 6.99    -34.199 5.953   1    36.51  ? 204 PRO A CD  1 
ATOM   3774 N  N   . GLY B 2 209 ? 8.039   -30.193 5.286   1    40.8   ? 205 GLY A N   1 
ATOM   3775 C  CA  . GLY B 2 209 ? 9.078   -29.509 4.499   1    43.1   ? 205 GLY A CA  1 
ATOM   3776 C  C   . GLY B 2 209 ? 9.825   -28.411 5.211   1    45.43  ? 205 GLY A C   1 
ATOM   3777 O  O   . GLY B 2 209 ? 9.332   -27.927 6.239   1    48.39  ? 205 GLY A O   1 
ATOM   3778 N  N   . ASP B 2 210 ? 10.961  -28.003 4.647   1    48.63  ? 206 ASP A N   1 
ATOM   3779 C  CA  . ASP B 2 210 ? 11.831  -26.986 5.294   1    56.49  ? 206 ASP A CA  1 
ATOM   3780 C  C   . ASP B 2 210 ? 11.747  -25.676 4.516   1    52.17  ? 206 ASP A C   1 
ATOM   3781 O  O   . ASP B 2 210 ? 12.129  -24.644 5.082   1    57.28  ? 206 ASP A O   1 
ATOM   3782 C  CB  . ASP B 2 210 ? 13.244  -27.522 5.45    1    64.25  ? 206 ASP A CB  1 
ATOM   3783 C  CG  . ASP B 2 210 ? 13.343  -28.984 5.852   1    76.44  ? 206 ASP A CG  1 
ATOM   3784 O  OD1 . ASP B 2 210 ? 12.746  -29.349 6.883   1    85.04  ? 206 ASP A OD1 1 
ATOM   3785 O  OD2 . ASP B 2 210 ? 14.014  -29.746 5.131   1    76.3   ? 206 ASP A OD2 1 
ATOM   3786 N  N   . SER B 2 211 ? 11.16   -25.672 3.366   1    46.95  ? 207 SER A N   1 
ATOM   3787 C  CA  . SER B 2 211 ? 11.076  -24.479 2.53    1    45.25  ? 207 SER A CA  1 
ATOM   3788 C  C   . SER B 2 211 ? 9.915   -24.66  1.571   1    43.22  ? 207 SER A C   1 
ATOM   3789 O  O   . SER B 2 211 ? 9.388   -25.765 1.472   1    43.9   ? 207 SER A O   1 
ATOM   3790 C  CB  . SER B 2 211 ? 12.349  -24.235 1.752   1    45.94  ? 207 SER A CB  1 
ATOM   3791 O  OG  . SER B 2 211 ? 12.796  -25.442 1.154   1    45.44  ? 207 SER A OG  1 
ATOM   3792 N  N   . GLU B 2 212 ? 9.526   -23.592 0.866   1    43.47  ? 208 GLU A N   1 
ATOM   3793 C  CA  . GLU B 2 212 ? 8.462   -23.721 -0.12   1    43.52  ? 208 GLU A CA  1 
ATOM   3794 C  C   . GLU B 2 212 ? 8.804   -24.807 -1.152  1    42.82  ? 208 GLU A C   1 
ATOM   3795 O  O   . GLU B 2 212 ? 7.966   -25.65  -1.455  1    42.77  ? 208 GLU A O   1 
ATOM   3796 C  CB  . GLU B 2 212 ? 8.226   -22.377 -0.803  1    47.79  ? 208 GLU A CB  1 
ATOM   3797 C  CG  . GLU B 2 212 ? 7.195   -21.457 -0.147  1    50.89  ? 208 GLU A CG  1 
ATOM   3798 C  CD  . GLU B 2 212 ? 7.103   -20.14  -0.923  1    59.73  ? 208 GLU A CD  1 
ATOM   3799 O  OE1 . GLU B 2 212 ? 6.11    -19.772 -1.62   1    61.57  ? 208 GLU A OE1 1 
ATOM   3800 O  OE2 . GLU B 2 212 ? 8.136   -19.439 -0.83   1    70.57  ? 208 GLU A OE2 1 
ATOM   3801 N  N   . ILE B 2 213 ? 10.049  -24.827 -1.659  1    42.66  ? 209 ILE A N   1 
ATOM   3802 C  CA  . ILE B 2 213 ? 10.435  -25.73  -2.737  1    43.54  ? 209 ILE A CA  1 
ATOM   3803 C  C   . ILE B 2 213 ? 10.602  -27.16  -2.207  1    43.06  ? 209 ILE A C   1 
ATOM   3804 O  O   . ILE B 2 213 ? 10.251  -28.13  -2.874  1    41.18  ? 209 ILE A O   1 
ATOM   3805 C  CB  . ILE B 2 213 ? 11.685  -25.227 -3.497  1    43.19  ? 209 ILE A CB  1 
ATOM   3806 C  CG1 . ILE B 2 213 ? 11.861  -25.942 -4.811  1    44.85  ? 209 ILE A CG1 1 
ATOM   3807 C  CG2 . ILE B 2 213 ? 12.942  -25.394 -2.67   1    44.91  ? 209 ILE A CG2 1 
ATOM   3808 C  CD1 . ILE B 2 213 ? 10.732  -25.7   -5.8    1    46.94  ? 209 ILE A CD1 1 
ATOM   3809 N  N   . ASP B 2 214 ? 11.139  -27.282 -0.99   1    44.46  ? 210 ASP A N   1 
ATOM   3810 C  CA  . ASP B 2 214 ? 11.244  -28.558 -0.315  1    43.36  ? 210 ASP A CA  1 
ATOM   3811 C  C   . ASP B 2 214 ? 9.872   -29.156 -0.064  1    41.58  ? 210 ASP A C   1 
ATOM   3812 O  O   . ASP B 2 214 ? 9.716   -30.371 -0.118  1    44.61  ? 210 ASP A O   1 
ATOM   3813 C  CB  . ASP B 2 214 ? 11.929  -28.453 1.031   1    49.49  ? 210 ASP A CB  1 
ATOM   3814 C  CG  . ASP B 2 214 ? 12.214  -29.809 1.666   1    54.29  ? 210 ASP A CG  1 
ATOM   3815 O  OD1 . ASP B 2 214 ? 12.699  -30.715 0.936   1    55.57  ? 210 ASP A OD1 1 
ATOM   3816 O  OD2 . ASP B 2 214 ? 11.951  -29.95  2.877   1    53.89  ? 210 ASP A OD2 1 
ATOM   3817 N  N   . GLN B 2 215 ? 8.898   -28.302 0.241   1    39.69  ? 211 GLN A N   1 
ATOM   3818 C  CA  . GLN B 2 215 ? 7.537   -28.746 0.495   1    38.44  ? 211 GLN A CA  1 
ATOM   3819 C  C   . GLN B 2 215 ? 6.928   -29.323 -0.788  1    37.67  ? 211 GLN A C   1 
ATOM   3820 O  O   . GLN B 2 215 ? 6.324   -30.401 -0.745  1    37.27  ? 211 GLN A O   1 
ATOM   3821 C  CB  . GLN B 2 215 ? 6.727   -27.576 1.056   1    37.83  ? 211 GLN A CB  1 
ATOM   3822 C  CG  . GLN B 2 215 ? 5.303   -27.927 1.475   1    35.13  ? 211 GLN A CG  1 
ATOM   3823 C  CD  . GLN B 2 215 ? 5.334   -28.669 2.777   1    35.55  ? 211 GLN A CD  1 
ATOM   3824 O  OE1 . GLN B 2 215 ? 6.311   -28.532 3.511   1    39.74  ? 211 GLN A OE1 1 
ATOM   3825 N  NE2 . GLN B 2 215 ? 4.323   -29.479 3.056   1    33.15  ? 211 GLN A NE2 1 
ATOM   3826 N  N   . LEU B 2 216 ? 7.075   -28.612 -1.921  1    35.96  ? 212 LEU A N   1 
ATOM   3827 C  CA  . LEU B 2 216 ? 6.556   -29.11  -3.191  1    36.83  ? 212 LEU A CA  1 
ATOM   3828 C  C   . LEU B 2 216 ? 7.154   -30.47  -3.492  1    39.03  ? 212 LEU A C   1 
ATOM   3829 O  O   . LEU B 2 216 ? 6.428   -31.377 -3.889  1    38.43  ? 212 LEU A O   1 
ATOM   3830 C  CB  . LEU B 2 216 ? 6.884   -28.218 -4.384  1    37.85  ? 212 LEU A CB  1 
ATOM   3831 C  CG  . LEU B 2 216 ? 5.942   -27.046 -4.594  1    42.71  ? 212 LEU A CG  1 
ATOM   3832 C  CD1 . LEU B 2 216 ? 6.603   -26.145 -5.614  1    44.64  ? 212 LEU A CD1 1 
ATOM   3833 C  CD2 . LEU B 2 216 ? 4.545   -27.539 -5.024  1    38.68  ? 212 LEU A CD2 1 
ATOM   3834 N  N   . PHE B 2 217 ? 8.497   -30.54  -3.387  1    37.98  ? 213 PHE A N   1 
ATOM   3835 C  CA  . PHE B 2 217 ? 9.214   -31.75  -3.719  1    35.58  ? 213 PHE A CA  1 
ATOM   3836 C  C   . PHE B 2 217 ? 8.696   -32.893 -2.855  1    39.11  ? 213 PHE A C   1 
ATOM   3837 O  O   . PHE B 2 217 ? 8.484   -33.982 -3.371  1    45.43  ? 213 PHE A O   1 
ATOM   3838 C  CB  . PHE B 2 217 ? 10.723  -31.543 -3.682  1    34.28  ? 213 PHE A CB  1 
ATOM   3839 C  CG  . PHE B 2 217 ? 11.209  -30.716 -4.857  1    34.73  ? 213 PHE A CG  1 
ATOM   3840 C  CD1 . PHE B 2 217 ? 10.309  -30.191 -5.795  1    32.6   ? 213 PHE A CD1 1 
ATOM   3841 C  CD2 . PHE B 2 217 ? 12.564  -30.429 -5.002  1    35.28  ? 213 PHE A CD2 1 
ATOM   3842 C  CE1 . PHE B 2 217 ? 10.766  -29.438 -6.862  1    32.82  ? 213 PHE A CE1 1 
ATOM   3843 C  CE2 . PHE B 2 217 ? 13.013  -29.658 -6.077  1    35.33  ? 213 PHE A CE2 1 
ATOM   3844 C  CZ  . PHE B 2 217 ? 12.113  -29.179 -7.006  1    33.93  ? 213 PHE A CZ  1 
ATOM   3845 N  N   . ARG B 2 218 ? 8.459   -32.648 -1.563  1    38.67  ? 214 ARG A N   1 
ATOM   3846 C  CA  . ARG B 2 218 ? 8.031   -33.726 -0.68   1    41.69  ? 214 ARG A CA  1 
ATOM   3847 C  C   . ARG B 2 218 ? 6.68    -34.279 -1.135  1    40.26  ? 214 ARG A C   1 
ATOM   3848 O  O   . ARG B 2 218 ? 6.446   -35.49  -1.052  1    41.68  ? 214 ARG A O   1 
ATOM   3849 C  CB  . ARG B 2 218 ? 7.976   -33.307 0.798   1    40.31  ? 214 ARG A CB  1 
ATOM   3850 C  CG  . ARG B 2 218 ? 9.258   -33.575 1.565   1    42.48  ? 214 ARG A CG  1 
ATOM   3851 C  CD  . ARG B 2 218 ? 9.435   -32.6   2.694   1    43.96  ? 214 ARG A CD  1 
ATOM   3852 N  NE  . ARG B 2 218 ? 10.784  -32.616 3.274   1    42.53  ? 214 ARG A NE  1 
ATOM   3853 C  CZ  . ARG B 2 218 ? 11.124  -33.504 4.181   1    41.24  ? 214 ARG A CZ  1 
ATOM   3854 N  NH1 . ARG B 2 218 ? 10.319  -34.542 4.416   1    40.98  ? 214 ARG A NH1 1 
ATOM   3855 N  NH2 . ARG B 2 218 ? 12.24   -33.315 4.844   1    39.33  ? 214 ARG A NH2 1 
ATOM   3856 N  N   . ILE B 2 219 ? 5.812   -33.354 -1.566  1    36.57  ? 215 ILE A N   1 
ATOM   3857 C  CA  . ILE B 2 219 ? 4.465   -33.651 -2.016  1    37.29  ? 215 ILE A CA  1 
ATOM   3858 C  C   . ILE B 2 219 ? 4.531   -34.452 -3.316  1    38.84  ? 215 ILE A C   1 
ATOM   3859 O  O   . ILE B 2 219 ? 3.854   -35.473 -3.436  1    38.96  ? 215 ILE A O   1 
ATOM   3860 C  CB  . ILE B 2 219 ? 3.649   -32.356 -2.206  1    34.98  ? 215 ILE A CB  1 
ATOM   3861 C  CG1 . ILE B 2 219 ? 3.357   -31.672 -0.882  1    33.42  ? 215 ILE A CG1 1 
ATOM   3862 C  CG2 . ILE B 2 219 ? 2.359   -32.669 -2.961  1    33.57  ? 215 ILE A CG2 1 
ATOM   3863 C  CD1 . ILE B 2 219 ? 2.696   -30.31  -1.007  1    32.92  ? 215 ILE A CD1 1 
ATOM   3864 N  N   . PHE B 2 220 ? 5.286   -33.919 -4.298  1    37.78  ? 216 PHE A N   1 
ATOM   3865 C  CA  . PHE B 2 220 ? 5.556   -34.57  -5.573  1    36.79  ? 216 PHE A CA  1 
ATOM   3866 C  C   . PHE B 2 220 ? 6.118   -35.984 -5.372  1    35.86  ? 216 PHE A C   1 
ATOM   3867 O  O   . PHE B 2 220 ? 5.764   -36.885 -6.123  1    37.13  ? 216 PHE A O   1 
ATOM   3868 C  CB  . PHE B 2 220 ? 6.545   -33.766 -6.416  1    34.51  ? 216 PHE A CB  1 
ATOM   3869 C  CG  . PHE B 2 220 ? 6.061   -32.423 -6.947  1    33.7   ? 216 PHE A CG  1 
ATOM   3870 C  CD1 . PHE B 2 220 ? 4.811   -31.916 -6.622  1    30.69  ? 216 PHE A CD1 1 
ATOM   3871 C  CD2 . PHE B 2 220 ? 6.882   -31.665 -7.777  1    35.17  ? 216 PHE A CD2 1 
ATOM   3872 C  CE1 . PHE B 2 220 ? 4.398   -30.696 -7.139  1    31.9   ? 216 PHE A CE1 1 
ATOM   3873 C  CE2 . PHE B 2 220 ? 6.454   -30.443 -8.295  1    34.22  ? 216 PHE A CE2 1 
ATOM   3874 C  CZ  . PHE B 2 220 ? 5.225   -29.95  -7.956  1    31.87  ? 216 PHE A CZ  1 
ATOM   3875 N  N   . ARG B 2 221 ? 6.982   -36.186 -4.378  1    34.59  ? 217 ARG A N   1 
ATOM   3876 C  CA  . ARG B 2 221 ? 7.595   -37.487 -4.163  1    36.28  ? 217 ARG A CA  1 
ATOM   3877 C  C   . ARG B 2 221 ? 6.55    -38.464 -3.634  1    38.36  ? 217 ARG A C   1 
ATOM   3878 O  O   . ARG B 2 221 ? 6.744   -39.664 -3.751  1    39.77  ? 217 ARG A O   1 
ATOM   3879 C  CB  . ARG B 2 221 ? 8.863   -37.418 -3.308  1    35.43  ? 217 ARG A CB  1 
ATOM   3880 C  CG  . ARG B 2 221 ? 10.08   -36.981 -4.119  1    37.82  ? 217 ARG A CG  1 
ATOM   3881 C  CD  . ARG B 2 221 ? 11.456  -37.268 -3.514  1    39.29  ? 217 ARG A CD  1 
ATOM   3882 N  NE  . ARG B 2 221 ? 11.551  -36.599 -2.215  1    44.74  ? 217 ARG A NE  1 
ATOM   3883 C  CZ  . ARG B 2 221 ? 11.905  -35.334 -1.945  1    45.53  ? 217 ARG A CZ  1 
ATOM   3884 N  NH1 . ARG B 2 221 ? 11.611  -34.827 -0.762  1    42.18  ? 217 ARG A NH1 1 
ATOM   3885 N  NH2 . ARG B 2 221 ? 12.489  -34.575 -2.86   1    43.95  ? 217 ARG A NH2 1 
ATOM   3886 N  N   . THR B 2 222 ? 5.411   -37.95  -3.153  1    37.71  ? 218 THR A N   1 
ATOM   3887 C  CA  . THR B 2 222 ? 4.385   -38.759 -2.505  1    40.06  ? 218 THR A CA  1 
ATOM   3888 C  C   . THR B 2 222 ? 3.201   -39.021 -3.441  1    39.2   ? 218 THR A C   1 
ATOM   3889 O  O   . THR B 2 222 ? 2.67    -40.121 -3.435  1    45.55  ? 218 THR A O   1 
ATOM   3890 C  CB  . THR B 2 222 ? 3.916   -38.098 -1.202  1    41.33  ? 218 THR A CB  1 
ATOM   3891 O  OG1 . THR B 2 222 ? 5.058   -38.08  -0.351  1    45.06  ? 218 THR A OG1 1 
ATOM   3892 C  CG2 . THR B 2 222 ? 2.789   -38.85  -0.505  1    39.21  ? 218 THR A CG2 1 
ATOM   3893 N  N   . LEU B 2 223 ? 2.792   -38.028 -4.231  1    33.61  ? 219 LEU A N   1 
ATOM   3894 C  CA  . LEU B 2 223 ? 1.603   -38.129 -5.052  1    34.79  ? 219 LEU A CA  1 
ATOM   3895 C  C   . LEU B 2 223 ? 1.967   -38.082 -6.539  1    37.08  ? 219 LEU A C   1 
ATOM   3896 O  O   . LEU B 2 223 ? 1.076   -38.011 -7.399  1    37.16  ? 219 LEU A O   1 
ATOM   3897 C  CB  . LEU B 2 223 ? 0.727   -36.938 -4.673  1    35.28  ? 219 LEU A CB  1 
ATOM   3898 C  CG  . LEU B 2 223 ? 0.352   -36.811 -3.191  1    37.51  ? 219 LEU A CG  1 
ATOM   3899 C  CD1 . LEU B 2 223 ? -0.477  -35.554 -2.963  1    34.92  ? 219 LEU A CD1 1 
ATOM   3900 C  CD2 . LEU B 2 223 ? -0.442  -38.02  -2.709  1    37.6   ? 219 LEU A CD2 1 
ATOM   3901 N  N   . GLY B 2 224 ? 3.278   -38.12  -6.821  1    35.1   ? 220 GLY A N   1 
ATOM   3902 C  CA  . GLY B 2 224 ? 3.835   -37.931 -8.145  1    34.51  ? 220 GLY A CA  1 
ATOM   3903 C  C   . GLY B 2 224 ? 3.857   -36.449 -8.513  1    37.28  ? 220 GLY A C   1 
ATOM   3904 O  O   . GLY B 2 224 ? 3.12    -35.644 -7.936  1    36.6   ? 220 GLY A O   1 
ATOM   3905 N  N   . THR B 2 225 ? 4.739   -36.107 -9.459  1    37.14  ? 221 THR A N   1 
ATOM   3906 C  CA  . THR B 2 225 ? 4.858   -34.758 -9.971  1    38.42  ? 221 THR A CA  1 
ATOM   3907 C  C   . THR B 2 225 ? 3.681   -34.583 -10.911 1    41.64  ? 221 THR A C   1 
ATOM   3908 O  O   . THR B 2 225 ? 3.549   -35.342 -11.861 1    48.59  ? 221 THR A O   1 
ATOM   3909 C  CB  . THR B 2 225 ? 6.187   -34.53  -10.709 1    42.26  ? 221 THR A CB  1 
ATOM   3910 O  OG1 . THR B 2 225 ? 7.323   -34.897 -9.926  1    45.75  ? 221 THR A OG1 1 
ATOM   3911 C  CG2 . THR B 2 225 ? 6.374   -33.097 -11.181 1    37.94  ? 221 THR A CG2 1 
ATOM   3912 N  N   . PRO B 2 226 ? 2.822   -33.561 -10.72  1    42.95  ? 222 PRO A N   1 
ATOM   3913 C  CA  . PRO B 2 226 ? 1.633   -33.406 -11.568 1    43.19  ? 222 PRO A CA  1 
ATOM   3914 C  C   . PRO B 2 226 ? 1.931   -32.888 -12.978 1    47.75  ? 222 PRO A C   1 
ATOM   3915 O  O   . PRO B 2 226 ? 2.809   -32.049 -13.17  1    50.7   ? 222 PRO A O   1 
ATOM   3916 C  CB  . PRO B 2 226 ? 0.841   -32.381 -10.738 1    43.53  ? 222 PRO A CB  1 
ATOM   3917 C  CG  . PRO B 2 226 ? 1.919   -31.481 -10.118 1    42.31  ? 222 PRO A CG  1 
ATOM   3918 C  CD  . PRO B 2 226 ? 3.012   -32.467 -9.747  1    39.21  ? 222 PRO A CD  1 
ATOM   3919 N  N   . ASP B 2 227 ? 1.191   -33.378 -13.976 1    49.37  ? 223 ASP A N   1 
ATOM   3920 C  CA  . ASP B 2 227 ? 1.319   -32.87  -15.336 1    49.38  ? 223 ASP A CA  1 
ATOM   3921 C  C   . ASP B 2 227 ? -0.047  -32.328 -15.773 1    50.87  ? 223 ASP A C   1 
ATOM   3922 O  O   . ASP B 2 227 ? -0.971  -32.201 -14.956 1    43.63  ? 223 ASP A O   1 
ATOM   3923 C  CB  . ASP B 2 227 ? 1.768   -33.989 -16.259 1    49.69  ? 223 ASP A CB  1 
ATOM   3924 C  CG  . ASP B 2 227 ? 0.889   -35.219 -16.098 1    56.1   ? 223 ASP A CG  1 
ATOM   3925 O  OD1 . ASP B 2 227 ? -0.34   -35.04  -15.971 1    60.99  ? 223 ASP A OD1 1 
ATOM   3926 O  OD2 . ASP B 2 227 ? 1.408   -36.335 -16.103 1    61.51  ? 223 ASP A OD2 1 
ATOM   3927 N  N   . GLU B 2 228 ? -0.183  -32.074 -17.083 1    53.2   ? 224 GLU A N   1 
ATOM   3928 C  CA  . GLU B 2 228 ? -1.395  -31.496 -17.642 1    52.79  ? 224 GLU A CA  1 
ATOM   3929 C  C   . GLU B 2 228 ? -2.565  -32.486 -17.587 1    53     ? 224 GLU A C   1 
ATOM   3930 O  O   . GLU B 2 228 ? -3.712  -32.049 -17.528 1    51.88  ? 224 GLU A O   1 
ATOM   3931 C  CB  . GLU B 2 228 ? -1.126  -30.955 -19.047 1    51.71  ? 224 GLU A CB  1 
ATOM   3932 C  CG  . GLU B 2 228 ? -0.31   -29.671 -19.047 1    50.3   ? 224 GLU A CG  1 
ATOM   3933 C  CD  . GLU B 2 228 ? -1.085  -28.438 -18.601 1    57.8   ? 224 GLU A CD  1 
ATOM   3934 O  OE1 . GLU B 2 228 ? -2.339  -28.435 -18.64  1    53.5   ? 224 GLU A OE1 1 
ATOM   3935 O  OE2 . GLU B 2 228 ? -0.421  -27.458 -18.185 1    59.73  ? 224 GLU A OE2 1 
ATOM   3936 N  N   . VAL B 2 229 ? -2.28   -33.799 -17.552 1    48.07  ? 225 VAL A N   1 
ATOM   3937 C  CA  . VAL B 2 229 ? -3.324  -34.815 -17.49  1    48.04  ? 225 VAL A CA  1 
ATOM   3938 C  C   . VAL B 2 229 ? -3.97   -34.831 -16.104 1    48.57  ? 225 VAL A C   1 
ATOM   3939 O  O   . VAL B 2 229 ? -5.185  -34.835 -15.972 1    50.13  ? 225 VAL A O   1 
ATOM   3940 C  CB  . VAL B 2 229 ? -2.799  -36.221 -17.833 1    48.81  ? 225 VAL A CB  1 
ATOM   3941 C  CG1 . VAL B 2 229 ? -3.891  -37.277 -17.673 1    46.5   ? 225 VAL A CG1 1 
ATOM   3942 C  CG2 . VAL B 2 229 ? -2.14   -36.257 -19.211 1    47.54  ? 225 VAL A CG2 1 
ATOM   3943 N  N   . VAL B 2 230 ? -3.164  -34.912 -15.05  1    44.17  ? 226 VAL A N   1 
ATOM   3944 C  CA  . VAL B 2 230 ? -3.777  -34.984 -13.741 1    44.42  ? 226 VAL A CA  1 
ATOM   3945 C  C   . VAL B 2 230 ? -4.233  -33.59  -13.323 1    43.98  ? 226 VAL A C   1 
ATOM   3946 O  O   . VAL B 2 230 ? -5.193  -33.452 -12.572 1    43.48  ? 226 VAL A O   1 
ATOM   3947 C  CB  . VAL B 2 230 ? -2.908  -35.733 -12.702 1    44.9   ? 226 VAL A CB  1 
ATOM   3948 C  CG1 . VAL B 2 230 ? -3.519  -35.686 -11.316 1    51.63  ? 226 VAL A CG1 1 
ATOM   3949 C  CG2 . VAL B 2 230 ? -2.599  -37.167 -13.076 1    41.09  ? 226 VAL A CG2 1 
ATOM   3950 N  N   . TRP B 2 231 ? -3.552  -32.544 -13.794 1    46.3   ? 227 TRP A N   1 
ATOM   3951 C  CA  . TRP B 2 231 ? -3.923  -31.207 -13.342 1    45.56  ? 227 TRP A CA  1 
ATOM   3952 C  C   . TRP B 2 231 ? -3.841  -30.194 -14.478 1    45.55  ? 227 TRP A C   1 
ATOM   3953 O  O   . TRP B 2 231 ? -2.808  -29.569 -14.665 1    45.55  ? 227 TRP A O   1 
ATOM   3954 C  CB  . TRP B 2 231 ? -3.02   -30.797 -12.173 1    45.46  ? 227 TRP A CB  1 
ATOM   3955 C  CG  . TRP B 2 231 ? -3.39   -29.503 -11.499 1    46.53  ? 227 TRP A CG  1 
ATOM   3956 C  CD1 . TRP B 2 231 ? -4.473  -28.714 -11.74  1    44.47  ? 227 TRP A CD1 1 
ATOM   3957 C  CD2 . TRP B 2 231 ? -2.647  -28.86  -10.445 1    44.89  ? 227 TRP A CD2 1 
ATOM   3958 N  NE1 . TRP B 2 231 ? -4.454  -27.624 -10.917 1    44.88  ? 227 TRP A NE1 1 
ATOM   3959 C  CE2 . TRP B 2 231 ? -3.356  -27.69  -10.107 1    43.96  ? 227 TRP A CE2 1 
ATOM   3960 C  CE3 . TRP B 2 231 ? -1.473  -29.178 -9.748  1    43.86  ? 227 TRP A CE3 1 
ATOM   3961 C  CZ2 . TRP B 2 231 ? -2.924  -26.828 -9.105  1    42.49  ? 227 TRP A CZ2 1 
ATOM   3962 C  CZ3 . TRP B 2 231 ? -1.031  -28.324 -8.765  1    41.59  ? 227 TRP A CZ3 1 
ATOM   3963 C  CH2 . TRP B 2 231 ? -1.741  -27.155 -8.473  1    44.26  ? 227 TRP A CH2 1 
ATOM   3964 N  N   . PRO B 2 232 ? -4.922  -29.962 -15.25  1    49.63  ? 228 PRO A N   1 
ATOM   3965 C  CA  . PRO B 2 232 ? -4.889  -28.944 -16.311 1    53.15  ? 228 PRO A CA  1 
ATOM   3966 C  C   . PRO B 2 232 ? -4.595  -27.552 -15.739 1    54.03  ? 228 PRO A C   1 
ATOM   3967 O  O   . PRO B 2 232 ? -5.216  -27.148 -14.758 1    51.03  ? 228 PRO A O   1 
ATOM   3968 C  CB  . PRO B 2 232 ? -6.276  -29.041 -17.005 1    47.03  ? 228 PRO A CB  1 
ATOM   3969 C  CG  . PRO B 2 232 ? -6.819  -30.387 -16.547 1    46.57  ? 228 PRO A CG  1 
ATOM   3970 C  CD  . PRO B 2 232 ? -6.212  -30.668 -15.168 1    46.88  ? 228 PRO A CD  1 
ATOM   3971 N  N   . GLY B 2 233 ? -3.63   -26.841 -16.354 1    58.18  ? 229 GLY A N   1 
ATOM   3972 C  CA  . GLY B 2 233 ? -3.225  -25.516 -15.909 1    58.07  ? 229 GLY A CA  1 
ATOM   3973 C  C   . GLY B 2 233 ? -1.858  -25.498 -15.221 1    59.38  ? 229 GLY A C   1 
ATOM   3974 O  O   . GLY B 2 233 ? -1.212  -24.452 -15.196 1    63.03  ? 229 GLY A O   1 
ATOM   3975 N  N   . VAL B 2 234 ? -1.425  -26.662 -14.702 1    53.36  ? 230 VAL A N   1 
ATOM   3976 C  CA  . VAL B 2 234 ? -0.355  -26.755 -13.726 1    47.75  ? 230 VAL A CA  1 
ATOM   3977 C  C   . VAL B 2 234 ? 0.909   -26.161 -14.337 1    51.88  ? 230 VAL A C   1 
ATOM   3978 O  O   . VAL B 2 234 ? 1.57    -25.346 -13.699 1    52.94  ? 230 VAL A O   1 
ATOM   3979 C  CB  . VAL B 2 234 ? -0.097  -28.161 -13.145 1    41.28  ? 230 VAL A CB  1 
ATOM   3980 C  CG1 . VAL B 2 234 ? 0.581   -29.094 -14.135 1    37.13  ? 230 VAL A CG1 1 
ATOM   3981 C  CG2 . VAL B 2 234 ? 0.756   -28.104 -11.894 1    37.03  ? 230 VAL A CG2 1 
ATOM   3982 N  N   . THR B 2 235 ? 1.217   -26.587 -15.566 1    51.49  ? 231 THR A N   1 
ATOM   3983 C  CA  . THR B 2 235 ? 2.526   -26.323 -16.133 1    55.83  ? 231 THR A CA  1 
ATOM   3984 C  C   . THR B 2 235 ? 2.585   -24.871 -16.569 1    57.78  ? 231 THR A C   1 
ATOM   3985 O  O   . THR B 2 235 ? 3.628   -24.456 -17.054 1    65.46  ? 231 THR A O   1 
ATOM   3986 C  CB  . THR B 2 235 ? 2.952   -27.233 -17.295 1    55.71  ? 231 THR A CB  1 
ATOM   3987 O  OG1 . THR B 2 235 ? 1.972   -27.091 -18.311 1    59.35  ? 231 THR A OG1 1 
ATOM   3988 C  CG2 . THR B 2 235 ? 3.138   -28.697 -16.937 1    50.84  ? 231 THR A CG2 1 
ATOM   3989 N  N   . SER B 2 236 ? 1.485   -24.12  -16.425 1    56.83  ? 232 SER A N   1 
ATOM   3990 C  CA  . SER B 2 236 ? 1.541   -22.714 -16.803 1    63.52  ? 232 SER A CA  1 
ATOM   3991 C  C   . SER B 2 236 ? 1.36    -21.832 -15.568 1    62.19  ? 232 SER A C   1 
ATOM   3992 O  O   . SER B 2 236 ? 1.184   -20.627 -15.654 1    67.09  ? 232 SER A O   1 
ATOM   3993 C  CB  . SER B 2 236 ? 0.591   -22.354 -17.945 1    69.96  ? 232 SER A CB  1 
ATOM   3994 O  OG  . SER B 2 236 ? -0.757  -22.407 -17.505 1    79.33  ? 232 SER A OG  1 
ATOM   3995 N  N   . MET B 2 237 ? 1.439   -22.442 -14.393 1    61.42  ? 233 MET A N   1 
ATOM   3996 C  CA  . MET B 2 237 ? 1.324   -21.704 -13.145 1    58.73  ? 233 MET A CA  1 
ATOM   3997 C  C   . MET B 2 237 ? 2.554   -20.837 -12.861 1    54.57  ? 233 MET A C   1 
ATOM   3998 O  O   . MET B 2 237 ? 3.666   -21.213 -13.238 1    51.45  ? 233 MET A O   1 
ATOM   3999 C  CB  . MET B 2 237 ? 1.034   -22.674 -12.002 1    54.88  ? 233 MET A CB  1 
ATOM   4000 C  CG  . MET B 2 237 ? -0.434  -22.795 -11.866 1    60.16  ? 233 MET A CG  1 
ATOM   4001 S  SD  . MET B 2 237 ? -0.827  -24.337 -11.052 1    68.99  ? 233 MET A SD  1 
ATOM   4002 C  CE  . MET B 2 237 ? -2.48   -24.636 -11.691 1    77.46  ? 233 MET A CE  1 
ATOM   4003 N  N   . PRO B 2 238 ? 2.388   -19.693 -12.139 1    50.27  ? 234 PRO A N   1 
ATOM   4004 C  CA  . PRO B 2 238 ? 3.424   -18.658 -12.085 1    48.47  ? 234 PRO A CA  1 
ATOM   4005 C  C   . PRO B 2 238 ? 4.767   -19.155 -11.555 1    49.03  ? 234 PRO A C   1 
ATOM   4006 O  O   . PRO B 2 238 ? 5.812   -18.691 -12.007 1    52.92  ? 234 PRO A O   1 
ATOM   4007 C  CB  . PRO B 2 238 ? 2.788   -17.55  -11.197 1    45.15  ? 234 PRO A CB  1 
ATOM   4008 C  CG  . PRO B 2 238 ? 1.295   -17.835 -11.29  1    42.51  ? 234 PRO A CG  1 
ATOM   4009 C  CD  . PRO B 2 238 ? 1.219   -19.352 -11.294 1    43.09  ? 234 PRO A CD  1 
ATOM   4010 N  N   . ASP B 2 239 ? 4.732   -20.102 -10.608 1    47.31  ? 235 ASP A N   1 
ATOM   4011 C  CA  . ASP B 2 239 ? 5.951   -20.647 -10.039 1    48.36  ? 235 ASP A CA  1 
ATOM   4012 C  C   . ASP B 2 239 ? 6.15    -22.114 -10.411 1    52.21  ? 235 ASP A C   1 
ATOM   4013 O  O   . ASP B 2 239 ? 6.994   -22.776 -9.81   1    50.62  ? 235 ASP A O   1 
ATOM   4014 C  CB  . ASP B 2 239 ? 5.993   -20.476 -8.53   1    46.86  ? 235 ASP A CB  1 
ATOM   4015 C  CG  . ASP B 2 239 ? 5.932   -19.033 -8.077  1    45.58  ? 235 ASP A CG  1 
ATOM   4016 O  OD1 . ASP B 2 239 ? 6.563   -18.222 -8.726  1    49.63  ? 235 ASP A OD1 1 
ATOM   4017 O  OD2 . ASP B 2 239 ? 5.226   -18.733 -7.107  1    53.44  ? 235 ASP A OD2 1 
ATOM   4018 N  N   . TYR B 2 240 ? 5.39    -22.621 -11.392 1    55.07  ? 236 TYR A N   1 
ATOM   4019 C  CA  . TYR B 2 240 ? 5.712   -23.902 -12.01  1    54.26  ? 236 TYR A CA  1 
ATOM   4020 C  C   . TYR B 2 240 ? 6.999   -23.729 -12.821 1    52.45  ? 236 TYR A C   1 
ATOM   4021 O  O   . TYR B 2 240 ? 7.164   -22.728 -13.52  1    51.16  ? 236 TYR A O   1 
ATOM   4022 C  CB  . TYR B 2 240 ? 4.573   -24.451 -12.896 1    58.54  ? 236 TYR A CB  1 
ATOM   4023 C  CG  . TYR B 2 240 ? 4.962   -25.762 -13.566 1    60.31  ? 236 TYR A CG  1 
ATOM   4024 C  CD1 . TYR B 2 240 ? 4.925   -26.96  -12.86  1    65.69  ? 236 TYR A CD1 1 
ATOM   4025 C  CD2 . TYR B 2 240 ? 5.47    -25.787 -14.857 1    62.46  ? 236 TYR A CD2 1 
ATOM   4026 C  CE1 . TYR B 2 240 ? 5.36    -28.15  -13.425 1    69.8   ? 236 TYR A CE1 1 
ATOM   4027 C  CE2 . TYR B 2 240 ? 5.888   -26.973 -15.441 1    66.73  ? 236 TYR A CE2 1 
ATOM   4028 C  CZ  . TYR B 2 240 ? 5.84    -28.155 -14.726 1    70.18  ? 236 TYR A CZ  1 
ATOM   4029 O  OH  . TYR B 2 240 ? 6.256   -29.291 -15.36  1    76.3   ? 236 TYR A OH  1 
ATOM   4030 N  N   . LYS B 2 241 ? 7.88    -24.734 -12.763 1    49.77  ? 237 LYS A N   1 
ATOM   4031 C  CA  . LYS B 2 241 ? 9.104   -24.718 -13.535 1    48.88  ? 237 LYS A CA  1 
ATOM   4032 C  C   . LYS B 2 241 ? 9.21    -26.008 -14.34  1    46.75  ? 237 LYS A C   1 
ATOM   4033 O  O   . LYS B 2 241 ? 9.041   -27.084 -13.797 1    41.53  ? 237 LYS A O   1 
ATOM   4034 C  CB  . LYS B 2 241 ? 10.292  -24.481 -12.603 1    52.66  ? 237 LYS A CB  1 
ATOM   4035 C  CG  . LYS B 2 241 ? 10.439  -23.029 -12.16  1    62.88  ? 237 LYS A CG  1 
ATOM   4036 C  CD  . LYS B 2 241 ? 11.684  -22.726 -11.325 1    75.65  ? 237 LYS A CD  1 
ATOM   4037 C  CE  . LYS B 2 241 ? 11.703  -23.588 -10.077 1    83.79  ? 237 LYS A CE  1 
ATOM   4038 N  NZ  . LYS B 2 241 ? 12.564  -23.144 -8.971  1    81.29  ? 237 LYS A NZ  1 
ATOM   4039 N  N   . PRO B 2 242 ? 9.481   -25.941 -15.667 1    49.19  ? 238 PRO A N   1 
ATOM   4040 C  CA  . PRO B 2 242 ? 9.721   -27.138 -16.476 1    49.56  ? 238 PRO A CA  1 
ATOM   4041 C  C   . PRO B 2 242 ? 10.801  -28.068 -15.914 1    51.2   ? 238 PRO A C   1 
ATOM   4042 O  O   . PRO B 2 242 ? 10.793  -29.267 -16.171 1    51.08  ? 238 PRO A O   1 
ATOM   4043 C  CB  . PRO B 2 242 ? 10.133  -26.609 -17.878 1    50.32  ? 238 PRO A CB  1 
ATOM   4044 C  CG  . PRO B 2 242 ? 10.113  -25.092 -17.812 1    50.2   ? 238 PRO A CG  1 
ATOM   4045 C  CD  . PRO B 2 242 ? 9.596   -24.699 -16.44  1    49.86  ? 238 PRO A CD  1 
ATOM   4046 N  N   . SER B 2 243 ? 11.758  -27.492 -15.174 1    51.98  ? 239 SER A N   1 
ATOM   4047 C  CA  . SER B 2 243 ? 12.921  -28.199 -14.653 1    51.52  ? 239 SER A CA  1 
ATOM   4048 C  C   . SER B 2 243 ? 12.569  -29.123 -13.483 1    48.05  ? 239 SER A C   1 
ATOM   4049 O  O   . SER B 2 243 ? 13.394  -29.939 -13.1   1    48.7   ? 239 SER A O   1 
ATOM   4050 C  CB  . SER B 2 243 ? 14.004  -27.215 -14.251 1    52.71  ? 239 SER A CB  1 
ATOM   4051 O  OG  . SER B 2 243 ? 13.557  -26.438 -13.144 1    58.53  ? 239 SER A OG  1 
ATOM   4052 N  N   . PHE B 2 244 ? 11.382  -28.965 -12.884 1    46.62  ? 240 PHE A N   1 
ATOM   4053 C  CA  . PHE B 2 244 ? 10.936  -29.797 -11.771 1    46.93  ? 240 PHE A CA  1 
ATOM   4054 C  C   . PHE B 2 244 ? 11.17   -31.286 -12.028 1    48.3   ? 240 PHE A C   1 
ATOM   4055 O  O   . PHE B 2 244 ? 10.828  -31.815 -13.074 1    51.15  ? 240 PHE A O   1 
ATOM   4056 C  CB  . PHE B 2 244 ? 9.426   -29.703 -11.567 1    42.36  ? 240 PHE A CB  1 
ATOM   4057 C  CG  . PHE B 2 244 ? 8.983   -28.488 -10.768 1    46.19  ? 240 PHE A CG  1 
ATOM   4058 C  CD1 . PHE B 2 244 ? 9.909   -27.692 -10.108 1    48.38  ? 240 PHE A CD1 1 
ATOM   4059 C  CD2 . PHE B 2 244 ? 7.635   -28.165 -10.659 1    46.24  ? 240 PHE A CD2 1 
ATOM   4060 C  CE1 . PHE B 2 244 ? 9.505   -26.579 -9.383  1    49.51  ? 240 PHE A CE1 1 
ATOM   4061 C  CE2 . PHE B 2 244 ? 7.239   -27.059 -9.94   1    48.55  ? 240 PHE A CE2 1 
ATOM   4062 C  CZ  . PHE B 2 244 ? 8.171   -26.279 -9.292  1    48.81  ? 240 PHE A CZ  1 
ATOM   4063 N  N   . PRO B 2 245 ? 11.688  -32.062 -11.066 1    47.16  ? 241 PRO A N   1 
ATOM   4064 C  CA  . PRO B 2 245 ? 11.857  -33.492 -11.312 1    50.53  ? 241 PRO A CA  1 
ATOM   4065 C  C   . PRO B 2 245 ? 10.508  -34.195 -11.449 1    47.91  ? 241 PRO A C   1 
ATOM   4066 O  O   . PRO B 2 245 ? 9.524   -33.821 -10.818 1    43.45  ? 241 PRO A O   1 
ATOM   4067 C  CB  . PRO B 2 245 ? 12.707  -33.953 -10.107 1    50.07  ? 241 PRO A CB  1 
ATOM   4068 C  CG  . PRO B 2 245 ? 13.314  -32.657 -9.595  1    50.1   ? 241 PRO A CG  1 
ATOM   4069 C  CD  . PRO B 2 245 ? 12.189  -31.628 -9.757  1    47.14  ? 241 PRO A CD  1 
ATOM   4070 N  N   . LYS B 2 246 ? 10.477  -35.202 -12.328 1    51.72  ? 242 LYS A N   1 
ATOM   4071 C  CA  . LYS B 2 246 ? 9.278   -35.983 -12.615 1    52.44  ? 242 LYS A CA  1 
ATOM   4072 C  C   . LYS B 2 246 ? 9.288   -37.261 -11.778 1    46.05  ? 242 LYS A C   1 
ATOM   4073 O  O   . LYS B 2 246 ? 9.982   -38.202 -12.136 1    56.21  ? 242 LYS A O   1 
ATOM   4074 C  CB  . LYS B 2 246 ? 9.294   -36.392 -14.096 1    55.61  ? 242 LYS A CB  1 
ATOM   4075 C  CG  . LYS B 2 246 ? 8.368   -35.626 -15.019 1    65.63  ? 242 LYS A CG  1 
ATOM   4076 C  CD  . LYS B 2 246 ? 8.863   -34.311 -15.597 1    69.12  ? 242 LYS A CD  1 
ATOM   4077 C  CE  . LYS B 2 246 ? 8.132   -33.986 -16.857 1    74.11  ? 242 LYS A CE  1 
ATOM   4078 N  NZ  . LYS B 2 246 ? 8.655   -32.752 -17.442 1    74.56  ? 242 LYS A NZ  1 
ATOM   4079 N  N   . TRP B 2 247 ? 8.579   -37.267 -10.647 1    38.62  ? 243 TRP A N   1 
ATOM   4080 C  CA  . TRP B 2 247 ? 8.542   -38.431 -9.78   1    36.36  ? 243 TRP A CA  1 
ATOM   4081 C  C   . TRP B 2 247 ? 7.252   -39.189 -10.074 1    38.57  ? 243 TRP A C   1 
ATOM   4082 O  O   . TRP B 2 247 ? 6.178   -38.587 -10.192 1    37.05  ? 243 TRP A O   1 
ATOM   4083 C  CB  . TRP B 2 247 ? 8.58    -38.052 -8.288  1    33.56  ? 243 TRP A CB  1 
ATOM   4084 C  CG  . TRP B 2 247 ? 9.925   -37.7   -7.715  1    35.56  ? 243 TRP A CG  1 
ATOM   4085 C  CD1 . TRP B 2 247 ? 10.936  -38.555 -7.371  1    35.8   ? 243 TRP A CD1 1 
ATOM   4086 C  CD2 . TRP B 2 247 ? 10.395  -36.376 -7.364  1    36.27  ? 243 TRP A CD2 1 
ATOM   4087 N  NE1 . TRP B 2 247 ? 12.007  -37.86  -6.878  1    35.67  ? 243 TRP A NE1 1 
ATOM   4088 C  CE2 . TRP B 2 247 ? 11.707  -36.528 -6.854  1    36.94  ? 243 TRP A CE2 1 
ATOM   4089 C  CE3 . TRP B 2 247 ? 9.849   -35.086 -7.446  1    34.06  ? 243 TRP A CE3 1 
ATOM   4090 C  CZ2 . TRP B 2 247 ? 12.462  -35.437 -6.422  1    39.17  ? 243 TRP A CZ2 1 
ATOM   4091 C  CZ3 . TRP B 2 247 ? 10.584  -34.013 -6.99   1    34.22  ? 243 TRP A CZ3 1 
ATOM   4092 C  CH2 . TRP B 2 247 ? 11.876  -34.187 -6.496  1    36.83  ? 243 TRP A CH2 1 
ATOM   4093 N  N   . ALA B 2 248 ? 7.37    -40.515 -10.149 1    39.99  ? 244 ALA A N   1 
ATOM   4094 C  CA  . ALA B 2 248 ? 6.234   -41.411 -10.273 1    41.14  ? 244 ALA A CA  1 
ATOM   4095 C  C   . ALA B 2 248 ? 5.339   -41.278 -9.049  1    43.48  ? 244 ALA A C   1 
ATOM   4096 O  O   . ALA B 2 248 ? 5.811   -41.108 -7.924  1    50.52  ? 244 ALA A O   1 
ATOM   4097 C  CB  . ALA B 2 248 ? 6.754   -42.828 -10.402 1    40.65  ? 244 ALA A CB  1 
ATOM   4098 N  N   . ARG B 2 249 ? 4.033   -41.356 -9.272  1    45.21  ? 245 ARG A N   1 
ATOM   4099 C  CA  . ARG B 2 249 ? 3.094   -41.424 -8.159  1    47.53  ? 245 ARG A CA  1 
ATOM   4100 C  C   . ARG B 2 249 ? 3.15    -42.818 -7.54   1    51.9   ? 245 ARG A C   1 
ATOM   4101 O  O   . ARG B 2 249 ? 3.035   -43.824 -8.231  1    54.36  ? 245 ARG A O   1 
ATOM   4102 C  CB  . ARG B 2 249 ? 1.699   -41.187 -8.744  1    44.32  ? 245 ARG A CB  1 
ATOM   4103 C  CG  . ARG B 2 249 ? 0.596   -41.407 -7.725  1    46.53  ? 245 ARG A CG  1 
ATOM   4104 C  CD  . ARG B 2 249 ? -0.762  -41.122 -8.346  1    43.83  ? 245 ARG A CD  1 
ATOM   4105 N  NE  . ARG B 2 249 ? -1.766  -41.191 -7.278  1    46.49  ? 245 ARG A NE  1 
ATOM   4106 C  CZ  . ARG B 2 249 ? -2.229  -40.164 -6.563  1    44.55  ? 245 ARG A CZ  1 
ATOM   4107 N  NH1 . ARG B 2 249 ? -1.582  -39     -6.601  1    43.15  ? 245 ARG A NH1 1 
ATOM   4108 N  NH2 . ARG B 2 249 ? -3.285  -40.354 -5.771  1    37.37  ? 245 ARG A NH2 1 
ATOM   4109 N  N   . GLN B 2 250 ? 3.327   -42.909 -6.228  1    60.15  ? 246 GLN A N   1 
ATOM   4110 C  CA  . GLN B 2 250 ? 3.366   -44.248 -5.654  1    61.96  ? 246 GLN A CA  1 
ATOM   4111 C  C   . GLN B 2 250 ? 1.931   -44.646 -5.29   1    65.68  ? 246 GLN A C   1 
ATOM   4112 O  O   . GLN B 2 250 ? 1.065   -43.784 -5.084  1    60.71  ? 246 GLN A O   1 
ATOM   4113 C  CB  . GLN B 2 250 ? 4.298   -44.264 -4.445  1    58.58  ? 246 GLN A CB  1 
ATOM   4114 C  CG  . GLN B 2 250 ? 3.678   -43.573 -3.236  1    56.86  ? 246 GLN A CG  1 
ATOM   4115 C  CD  . GLN B 2 250 ? 4.684   -43.257 -2.151  1    61.99  ? 246 GLN A CD  1 
ATOM   4116 O  OE1 . GLN B 2 250 ? 4.661   -42.174 -1.563  1    69.95  ? 246 GLN A OE1 1 
ATOM   4117 N  NE2 . GLN B 2 250 ? 5.582   -44.189 -1.866  1    66.02  ? 246 GLN A NE2 1 
ATOM   4118 N  N   . ASP B 2 251 ? 1.686   -45.961 -5.22   1    63.22  ? 247 ASP A N   1 
ATOM   4119 C  CA  . ASP B 2 251 ? 0.414   -46.475 -4.732  1    61.82  ? 247 ASP A CA  1 
ATOM   4120 C  C   . ASP B 2 251 ? 0.035   -45.742 -3.455  1    53.59  ? 247 ASP A C   1 
ATOM   4121 O  O   . ASP B 2 251 ? 0.85    -45.515 -2.569  1    53.61  ? 247 ASP A O   1 
ATOM   4122 C  CB  . ASP B 2 251 ? 0.469   -47.957 -4.406  1    76.24  ? 247 ASP A CB  1 
ATOM   4123 C  CG  . ASP B 2 251 ? 1.148   -48.813 -5.466  1    104.46 ? 247 ASP A CG  1 
ATOM   4124 O  OD1 . ASP B 2 251 ? 0.486   -49.059 -6.499  1    111.77 ? 247 ASP A OD1 1 
ATOM   4125 O  OD2 . ASP B 2 251 ? 2.347   -49.185 -5.269  1    106.19 ? 247 ASP A OD2 1 
ATOM   4126 N  N   . PHE B 2 252 ? -1.237  -45.386 -3.371  1    52.54  ? 248 PHE A N   1 
ATOM   4127 C  CA  . PHE B 2 252 ? -1.756  -44.642 -2.241  1    48.9   ? 248 PHE A CA  1 
ATOM   4128 C  C   . PHE B 2 252 ? -1.737  -45.484 -0.961  1    47.9   ? 248 PHE A C   1 
ATOM   4129 O  O   . PHE B 2 252 ? -1.769  -44.953 0.152   1    49.46  ? 248 PHE A O   1 
ATOM   4130 C  CB  . PHE B 2 252 ? -3.141  -44.172 -2.702  1    47.44  ? 248 PHE A CB  1 
ATOM   4131 C  CG  . PHE B 2 252 ? -3.373  -42.842 -2.018  1    48.03  ? 248 PHE A CG  1 
ATOM   4132 C  CD1 . PHE B 2 252 ? -2.864  -41.682 -2.588  1    46.23  ? 248 PHE A CD1 1 
ATOM   4133 C  CD2 . PHE B 2 252 ? -3.969  -42.767 -0.776  1    44.47  ? 248 PHE A CD2 1 
ATOM   4134 C  CE1 . PHE B 2 252 ? -3.007  -40.462 -1.978  1    38.51  ? 248 PHE A CE1 1 
ATOM   4135 C  CE2 . PHE B 2 252 ? -4.103  -41.532 -0.165  1    47.17  ? 248 PHE A CE2 1 
ATOM   4136 C  CZ  . PHE B 2 252 ? -3.626  -40.388 -0.763  1    42.45  ? 248 PHE A CZ  1 
ATOM   4137 N  N   . SER B 2 253 ? -1.76   -46.815 -1.128  1    48.58  ? 249 SER A N   1 
ATOM   4138 C  CA  . SER B 2 253 ? -1.704  -47.756 -0.019  1    46.41  ? 249 SER A CA  1 
ATOM   4139 C  C   . SER B 2 253 ? -0.371  -47.653 0.702   1    47.72  ? 249 SER A C   1 
ATOM   4140 O  O   . SER B 2 253 ? -0.238  -48.152 1.813   1    51.22  ? 249 SER A O   1 
ATOM   4141 C  CB  . SER B 2 253 ? -1.933  -49.181 -0.467  1    48.31  ? 249 SER A CB  1 
ATOM   4142 O  OG  . SER B 2 253 ? -0.839  -49.681 -1.222  1    54.02  ? 249 SER A OG  1 
ATOM   4143 N  N   . LYS B 2 254 ? 0.631   -47.059 0.046   1    50.89  ? 250 LYS A N   1 
ATOM   4144 C  CA  . LYS B 2 254 ? 1.965   -46.979 0.63    1    50.94  ? 250 LYS A CA  1 
ATOM   4145 C  C   . LYS B 2 254 ? 2.114   -45.698 1.455   1    50.54  ? 250 LYS A C   1 
ATOM   4146 O  O   . LYS B 2 254 ? 2.972   -45.642 2.333   1    57.39  ? 250 LYS A O   1 
ATOM   4147 C  CB  . LYS B 2 254 ? 3.018   -47.173 -0.462  1    44.43  ? 250 LYS A CB  1 
ATOM   4148 C  CG  . LYS B 2 254 ? 3.069   -48.606 -0.943  1    45.82  ? 250 LYS A CG  1 
ATOM   4149 C  CD  . LYS B 2 254 ? 3.717   -49.56  0.049   1    48.06  ? 250 LYS A CD  1 
ATOM   4150 C  CE  . LYS B 2 254 ? 3.802   -50.971 -0.445  1    49.46  ? 250 LYS A CE  1 
ATOM   4151 N  NZ  . LYS B 2 254 ? 2.443   -51.498 -0.456  1    54.92  ? 250 LYS A NZ  1 
ATOM   4152 N  N   . VAL B 2 255 ? 1.247   -44.706 1.198   1    43.53  ? 251 VAL A N   1 
ATOM   4153 C  CA  . VAL B 2 255 ? 1.369   -43.383 1.772   1    42.48  ? 251 VAL A CA  1 
ATOM   4154 C  C   . VAL B 2 255 ? 0.965   -43.407 3.24    1    48.3   ? 251 VAL A C   1 
ATOM   4155 O  O   . VAL B 2 255 ? 1.576   -42.707 4.043   1    51.73  ? 251 VAL A O   1 
ATOM   4156 C  CB  . VAL B 2 255 ? 0.495   -42.391 0.999   1    40.57  ? 251 VAL A CB  1 
ATOM   4157 C  CG1 . VAL B 2 255 ? 0.392   -41.061 1.737   1    40.44  ? 251 VAL A CG1 1 
ATOM   4158 C  CG2 . VAL B 2 255 ? 1.011   -42.222 -0.421  1    41.64  ? 251 VAL A CG2 1 
ATOM   4159 N  N   . VAL B 2 256 ? -0.11   -44.145 3.556   1    49.91  ? 252 VAL A N   1 
ATOM   4160 C  CA  . VAL B 2 256 ? -0.566  -44.342 4.927   1    44.71  ? 252 VAL A CA  1 
ATOM   4161 C  C   . VAL B 2 256 ? -0.928  -45.815 5.062   1    44.01  ? 252 VAL A C   1 
ATOM   4162 O  O   . VAL B 2 256 ? -2.103  -46.173 5.083   1    42.15  ? 252 VAL A O   1 
ATOM   4163 C  CB  . VAL B 2 256 ? -1.749  -43.421 5.286   1    45.43  ? 252 VAL A CB  1 
ATOM   4164 C  CG1 . VAL B 2 256 ? -2.2    -43.604 6.731   1    41.58  ? 252 VAL A CG1 1 
ATOM   4165 C  CG2 . VAL B 2 256 ? -1.401  -41.956 4.998   1    43.38  ? 252 VAL A CG2 1 
ATOM   4166 N  N   . PRO B 2 257 ? 0.09    -46.705 5.134   1    43.44  ? 253 PRO A N   1 
ATOM   4167 C  CA  . PRO B 2 257 ? -0.141  -48.145 5.08    1    44.7   ? 253 PRO A CA  1 
ATOM   4168 C  C   . PRO B 2 257 ? -1.28   -48.655 5.951   1    46.63  ? 253 PRO A C   1 
ATOM   4169 O  O   . PRO B 2 257 ? -2.063  -49.453 5.478   1    54.36  ? 253 PRO A O   1 
ATOM   4170 C  CB  . PRO B 2 257 ? 1.206   -48.768 5.445   1    44.54  ? 253 PRO A CB  1 
ATOM   4171 C  CG  . PRO B 2 257 ? 2.196   -47.679 5.062   1    43.28  ? 253 PRO A CG  1 
ATOM   4172 C  CD  . PRO B 2 257 ? 1.511   -46.356 5.305   1    41.09  ? 253 PRO A CD  1 
ATOM   4173 N  N   . PRO B 2 258 ? -1.428  -48.276 7.24    1    50.19  ? 254 PRO A N   1 
ATOM   4174 C  CA  . PRO B 2 258 ? -2.465  -48.904 8.071   1    54.13  ? 254 PRO A CA  1 
ATOM   4175 C  C   . PRO B 2 258 ? -3.905  -48.478 7.778   1    54.69  ? 254 PRO A C   1 
ATOM   4176 O  O   . PRO B 2 258 ? -4.816  -48.801 8.529   1    59.92  ? 254 PRO A O   1 
ATOM   4177 C  CB  . PRO B 2 258 ? -2.019  -48.557 9.503   1    52.39  ? 254 PRO A CB  1 
ATOM   4178 C  CG  . PRO B 2 258 ? -1.247  -47.257 9.37    1    48.82  ? 254 PRO A CG  1 
ATOM   4179 C  CD  . PRO B 2 258 ? -0.604  -47.308 7.991   1    48.84  ? 254 PRO A CD  1 
ATOM   4180 N  N   . LEU B 2 259 ? -4.102  -47.755 6.673   1    51.9   ? 255 LEU A N   1 
ATOM   4181 C  CA  . LEU B 2 259 ? -5.397  -47.201 6.321   1    47.11  ? 255 LEU A CA  1 
ATOM   4182 C  C   . LEU B 2 259 ? -6.103  -48.143 5.353   1    50.98  ? 255 LEU A C   1 
ATOM   4183 O  O   . LEU B 2 259 ? -5.463  -48.645 4.435   1    50.78  ? 255 LEU A O   1 
ATOM   4184 C  CB  . LEU B 2 259 ? -5.116  -45.866 5.652   1    41.49  ? 255 LEU A CB  1 
ATOM   4185 C  CG  . LEU B 2 259 ? -6.274  -44.88  5.631   1    37.99  ? 255 LEU A CG  1 
ATOM   4186 C  CD1 . LEU B 2 259 ? -6.855  -44.698 7.013   1    39.8   ? 255 LEU A CD1 1 
ATOM   4187 C  CD2 . LEU B 2 259 ? -5.801  -43.565 5.093   1    34.9   ? 255 LEU A CD2 1 
ATOM   4188 N  N   . ASP B 2 260 ? -7.419  -48.329 5.569   1    52.69  ? 256 ASP A N   1 
ATOM   4189 C  CA  . ASP B 2 260 ? -8.3    -49.247 4.85    1    56.93  ? 256 ASP A CA  1 
ATOM   4190 C  C   . ASP B 2 260 ? -8.767  -48.598 3.537   1    53.52  ? 256 ASP A C   1 
ATOM   4191 O  O   . ASP B 2 260 ? -8.493  -47.432 3.268   1    49.54  ? 256 ASP A O   1 
ATOM   4192 C  CB  . ASP B 2 260 ? -9.479  -49.623 5.739   1    65.8   ? 256 ASP A CB  1 
ATOM   4193 C  CG  . ASP B 2 260 ? -10.13  -48.412 6.42    1    80.49  ? 256 ASP A CG  1 
ATOM   4194 O  OD1 . ASP B 2 260 ? -9.451  -47.755 7.284   1    81     ? 256 ASP A OD1 1 
ATOM   4195 O  OD2 . ASP B 2 260 ? -11.287 -48.074 6.051   1    68.24  ? 256 ASP A OD2 1 
ATOM   4196 N  N   . GLU B 2 261 ? -9.498  -49.35  2.709   1    54.02  ? 257 GLU A N   1 
ATOM   4197 C  CA  . GLU B 2 261 ? -9.902  -48.903 1.382   1    55.22  ? 257 GLU A CA  1 
ATOM   4198 C  C   . GLU B 2 261 ? -10.737 -47.61  1.428   1    52.8   ? 257 GLU A C   1 
ATOM   4199 O  O   . GLU B 2 261 ? -10.522 -46.714 0.613   1    48.61  ? 257 GLU A O   1 
ATOM   4200 C  CB  . GLU B 2 261 ? -10.657 -50.07  0.747   1    59.73  ? 257 GLU A CB  1 
ATOM   4201 C  CG  . GLU B 2 261 ? -10.657 -50.054 -0.78   1    67.92  ? 257 GLU A CG  1 
ATOM   4202 C  CD  . GLU B 2 261 ? -11.429 -51.25  -1.31   1    76.22  ? 257 GLU A CD  1 
ATOM   4203 O  OE1 . GLU B 2 261 ? -12.67  -51.202 -1.211  1    76.23  ? 257 GLU A OE1 1 
ATOM   4204 O  OE2 . GLU B 2 261 ? -10.806 -52.241 -1.757  1    83.67  ? 257 GLU A OE2 1 
ATOM   4205 N  N   . ASP B 2 262 ? -11.687 -47.506 2.373   1    48.39  ? 258 ASP A N   1 
ATOM   4206 C  CA  . ASP B 2 262 ? -12.522 -46.319 2.519   1    48.57  ? 258 ASP A CA  1 
ATOM   4207 C  C   . ASP B 2 262 ? -11.654 -45.125 2.928   1    46.08  ? 258 ASP A C   1 
ATOM   4208 O  O   . ASP B 2 262 ? -11.748 -44.047 2.36    1    42.69  ? 258 ASP A O   1 
ATOM   4209 C  CB  . ASP B 2 262 ? -13.688 -46.548 3.481   1    51.53  ? 258 ASP A CB  1 
ATOM   4210 C  CG  . ASP B 2 262 ? -14.839 -47.457 3.033   1    55.78  ? 258 ASP A CG  1 
ATOM   4211 O  OD1 . ASP B 2 262 ? -14.921 -47.766 1.827   1    53.02  ? 258 ASP A OD1 1 
ATOM   4212 O  OD2 . ASP B 2 262 ? -15.672 -47.861 3.901   1    58.63  ? 258 ASP A OD2 1 
ATOM   4213 N  N   . GLY B 2 263 ? -10.802 -45.299 3.942   1    48.12  ? 259 GLY A N   1 
ATOM   4214 C  CA  . GLY B 2 263 ? -9.876  -44.246 4.341   1    43.11  ? 259 GLY A CA  1 
ATOM   4215 C  C   . GLY B 2 263 ? -9.015  -43.761 3.179   1    39.87  ? 259 GLY A C   1 
ATOM   4216 O  O   . GLY B 2 263 ? -8.901  -42.557 2.975   1    37.65  ? 259 GLY A O   1 
ATOM   4217 N  N   . ARG B 2 264 ? -8.458  -44.694 2.393   1    38.41  ? 260 ARG A N   1 
ATOM   4218 C  CA  . ARG B 2 264 ? -7.568  -44.323 1.307   1    39.11  ? 260 ARG A CA  1 
ATOM   4219 C  C   . ARG B 2 264 ? -8.335  -43.531 0.264   1    38.23  ? 260 ARG A C   1 
ATOM   4220 O  O   . ARG B 2 264 ? -7.823  -42.546 -0.25   1    42.35  ? 260 ARG A O   1 
ATOM   4221 C  CB  . ARG B 2 264 ? -6.949  -45.505 0.559   1    42.92  ? 260 ARG A CB  1 
ATOM   4222 C  CG  . ARG B 2 264 ? -5.946  -46.251 1.428   1    47.35  ? 260 ARG A CG  1 
ATOM   4223 C  CD  . ARG B 2 264 ? -4.934  -47.08  0.644   1    46.22  ? 260 ARG A CD  1 
ATOM   4224 N  NE  . ARG B 2 264 ? -5.587  -48.129 -0.139  1    45.97  ? 260 ARG A NE  1 
ATOM   4225 C  CZ  . ARG B 2 264 ? -6.104  -49.223 0.386   1    46.21  ? 260 ARG A CZ  1 
ATOM   4226 N  NH1 . ARG B 2 264 ? -5.936  -49.501 1.666   1    44.53  ? 260 ARG A NH1 1 
ATOM   4227 N  NH2 . ARG B 2 264 ? -6.788  -50.041 -0.384  1    47.02  ? 260 ARG A NH2 1 
ATOM   4228 N  N   . SER B 2 265 ? -9.542  -43.998 -0.045  1    37.67  ? 261 SER A N   1 
ATOM   4229 C  CA  . SER B 2 265 ? -10.41  -43.343 -1.006  1    36.74  ? 261 SER A CA  1 
ATOM   4230 C  C   . SER B 2 265 ? -10.666 -41.884 -0.611  1    36.11  ? 261 SER A C   1 
ATOM   4231 O  O   . SER B 2 265 ? -10.582 -40.982 -1.451  1    37.3   ? 261 SER A O   1 
ATOM   4232 C  CB  . SER B 2 265 ? -11.694 -44.118 -1.152  1    38.28  ? 261 SER A CB  1 
ATOM   4233 O  OG  . SER B 2 265 ? -12.706 -43.291 -1.703  1    41.44  ? 261 SER A OG  1 
ATOM   4234 N  N   . LEU B 2 266 ? -10.999 -41.652 0.666   1    33.06  ? 262 LEU A N   1 
ATOM   4235 C  CA  . LEU B 2 266 ? -11.355 -40.314 1.096   1    33.74  ? 262 LEU A CA  1 
ATOM   4236 C  C   . LEU B 2 266 ? -10.102 -39.437 1.129   1    38.17  ? 262 LEU A C   1 
ATOM   4237 O  O   . LEU B 2 266 ? -10.109 -38.339 0.564   1    38.27  ? 262 LEU A O   1 
ATOM   4238 C  CB  . LEU B 2 266 ? -12.135 -40.371 2.408   1    31.86  ? 262 LEU A CB  1 
ATOM   4239 C  CG  . LEU B 2 266 ? -12.26  -39.061 3.191   1    31.81  ? 262 LEU A CG  1 
ATOM   4240 C  CD1 . LEU B 2 266 ? -13.053 -37.975 2.475   1    29.79  ? 262 LEU A CD1 1 
ATOM   4241 C  CD2 . LEU B 2 266 ? -12.859 -39.355 4.565   1    30.8   ? 262 LEU A CD2 1 
ATOM   4242 N  N   . LEU B 2 267 ? -8.996  -39.967 1.689   1    40.8   ? 263 LEU A N   1 
ATOM   4243 C  CA  . LEU B 2 267 ? -7.721  -39.255 1.721   1    39.29  ? 263 LEU A CA  1 
ATOM   4244 C  C   . LEU B 2 267 ? -7.255  -38.846 0.318   1    40.69  ? 263 LEU A C   1 
ATOM   4245 O  O   . LEU B 2 267 ? -6.828  -37.7   0.127   1    40.14  ? 263 LEU A O   1 
ATOM   4246 C  CB  . LEU B 2 267 ? -6.635  -40.021 2.464   1    37.18  ? 263 LEU A CB  1 
ATOM   4247 C  CG  . LEU B 2 267 ? -5.297  -39.292 2.568   1    35.49  ? 263 LEU A CG  1 
ATOM   4248 C  CD1 . LEU B 2 267 ? -5.418  -38.029 3.412   1    30.77  ? 263 LEU A CD1 1 
ATOM   4249 C  CD2 . LEU B 2 267 ? -4.199  -40.196 3.099   1    34.99  ? 263 LEU A CD2 1 
ATOM   4250 N  N   . SER B 2 268 ? -7.351  -39.76  -0.66   1    38.97  ? 264 SER A N   1 
ATOM   4251 C  CA  . SER B 2 268 ? -6.916  -39.417 -2.014  1    41.9   ? 264 SER A CA  1 
ATOM   4252 C  C   . SER B 2 268 ? -7.76   -38.28  -2.586  1    39.9   ? 264 SER A C   1 
ATOM   4253 O  O   . SER B 2 268 ? -7.219  -37.392 -3.24   1    43.22  ? 264 SER A O   1 
ATOM   4254 C  CB  . SER B 2 268 ? -6.875  -40.594 -2.961  1    39.43  ? 264 SER A CB  1 
ATOM   4255 O  OG  . SER B 2 268 ? -8.188  -41.117 -3.112  1    45.16  ? 264 SER A OG  1 
ATOM   4256 N  N   . GLN B 2 269 ? -9.07   -38.307 -2.321  1    35.3   ? 265 GLN A N   1 
ATOM   4257 C  CA  . GLN B 2 269 ? -9.942  -37.269 -2.831  1    33.97  ? 265 GLN A CA  1 
ATOM   4258 C  C   . GLN B 2 269 ? -9.692  -35.964 -2.086  1    34.67  ? 265 GLN A C   1 
ATOM   4259 O  O   . GLN B 2 269 ? -9.963  -34.892 -2.619  1    39.36  ? 265 GLN A O   1 
ATOM   4260 C  CB  . GLN B 2 269 ? -11.404 -37.691 -2.715  1    34.75  ? 265 GLN A CB  1 
ATOM   4261 C  CG  . GLN B 2 269 ? -11.73  -38.907 -3.573  1    37.02  ? 265 GLN A CG  1 
ATOM   4262 C  CD  . GLN B 2 269 ? -13.117 -39.449 -3.324  1    41.81  ? 265 GLN A CD  1 
ATOM   4263 O  OE1 . GLN B 2 269 ? -13.286 -40.56  -2.801  1    44.04  ? 265 GLN A OE1 1 
ATOM   4264 N  NE2 . GLN B 2 269 ? -14.127 -38.651 -3.659  1    41.73  ? 265 GLN A NE2 1 
ATOM   4265 N  N   . MET B 2 270 ? -9.189  -36.031 -0.845  1    32.27  ? 266 MET A N   1 
ATOM   4266 C  CA  . MET B 2 270 ? -8.868  -34.784 -0.167  1    34.8   ? 266 MET A CA  1 
ATOM   4267 C  C   . MET B 2 270 ? -7.533  -34.193 -0.649  1    40.48  ? 266 MET A C   1 
ATOM   4268 O  O   . MET B 2 270 ? -7.323  -32.981 -0.538  1    43.15  ? 266 MET A O   1 
ATOM   4269 C  CB  . MET B 2 270 ? -8.865  -34.955 1.352   1    32.22  ? 266 MET A CB  1 
ATOM   4270 C  CG  . MET B 2 270 ? -10.217 -35.279 1.908   1    32.74  ? 266 MET A CG  1 
ATOM   4271 S  SD  . MET B 2 270 ? -10.203 -35.608 3.685   1    36.35  ? 266 MET A SD  1 
ATOM   4272 C  CE  . MET B 2 270 ? -10.253 -33.906 4.292   1    27.48  ? 266 MET A CE  1 
ATOM   4273 N  N   . LEU B 2 271 ? -6.644  -35.048 -1.186  1    37.39  ? 267 LEU A N   1 
ATOM   4274 C  CA  . LEU B 2 271 ? -5.31   -34.638 -1.607  1    37.92  ? 267 LEU A CA  1 
ATOM   4275 C  C   . LEU B 2 271 ? -5.187  -34.61  -3.138  1    38.04  ? 267 LEU A C   1 
ATOM   4276 O  O   . LEU B 2 271 ? -4.09   -34.631 -3.666  1    39.06  ? 267 LEU A O   1 
ATOM   4277 C  CB  . LEU B 2 271 ? -4.253  -35.526 -0.939  1    35.29  ? 267 LEU A CB  1 
ATOM   4278 C  CG  . LEU B 2 271 ? -4.17   -35.463 0.596   1    35.7   ? 267 LEU A CG  1 
ATOM   4279 C  CD1 . LEU B 2 271 ? -3.027  -36.301 1.173   1    34.6   ? 267 LEU A CD1 1 
ATOM   4280 C  CD2 . LEU B 2 271 ? -4.02   -34.05  1.141   1    32.93  ? 267 LEU A CD2 1 
ATOM   4281 N  N   . HIS B 2 272 ? -6.299  -34.518 -3.868  1    38.07  ? 268 HIS A N   1 
ATOM   4282 C  CA  . HIS B 2 272 ? -6.232  -34.411 -5.317  1    40.87  ? 268 HIS A CA  1 
ATOM   4283 C  C   . HIS B 2 272 ? -5.549  -33.094 -5.695  1    42.54  ? 268 HIS A C   1 
ATOM   4284 O  O   . HIS B 2 272 ? -5.813  -32.053 -5.068  1    39.42  ? 268 HIS A O   1 
ATOM   4285 C  CB  . HIS B 2 272 ? -7.64   -34.556 -5.901  1    42.92  ? 268 HIS A CB  1 
ATOM   4286 C  CG  . HIS B 2 272 ? -7.737  -34.835 -7.359  1    56.47  ? 268 HIS A CG  1 
ATOM   4287 N  ND1 . HIS B 2 272 ? -8.431  -35.941 -7.807  1    71.16  ? 268 HIS A ND1 1 
ATOM   4288 C  CD2 . HIS B 2 272 ? -7.281  -34.212 -8.467  1    62.05  ? 268 HIS A CD2 1 
ATOM   4289 C  CE1 . HIS B 2 272 ? -8.417  -35.966 -9.143  1    70.76  ? 268 HIS A CE1 1 
ATOM   4290 N  NE2 . HIS B 2 272 ? -7.719  -34.929 -9.56   1    69.49  ? 268 HIS A NE2 1 
ATOM   4291 N  N   . TYR B 2 273 ? -4.693  -33.16  -6.735  1    38.47  ? 269 TYR A N   1 
ATOM   4292 C  CA  . TYR B 2 273 ? -3.901  -32.016 -7.138  1    38.46  ? 269 TYR A CA  1 
ATOM   4293 C  C   . TYR B 2 273 ? -4.823  -30.894 -7.601  1    42.24  ? 269 TYR A C   1 
ATOM   4294 O  O   . TYR B 2 273 ? -4.718  -29.764 -7.11   1    47.26  ? 269 TYR A O   1 
ATOM   4295 C  CB  . TYR B 2 273 ? -2.829  -32.352 -8.174  1    37.62  ? 269 TYR A CB  1 
ATOM   4296 C  CG  . TYR B 2 273 ? -1.497  -32.834 -7.624  1    38.59  ? 269 TYR A CG  1 
ATOM   4297 C  CD1 . TYR B 2 273 ? -0.572  -31.939 -7.11   1    38.63  ? 269 TYR A CD1 1 
ATOM   4298 C  CD2 . TYR B 2 273 ? -1.155  -34.18  -7.649  1    40.37  ? 269 TYR A CD2 1 
ATOM   4299 C  CE1 . TYR B 2 273 ? 0.656   -32.369 -6.636  1    41.25  ? 269 TYR A CE1 1 
ATOM   4300 C  CE2 . TYR B 2 273 ? 0.068   -34.623 -7.17   1    42.51  ? 269 TYR A CE2 1 
ATOM   4301 C  CZ  . TYR B 2 273 ? 0.982   -33.716 -6.655  1    43.54  ? 269 TYR A CZ  1 
ATOM   4302 O  OH  . TYR B 2 273 ? 2.197   -34.133 -6.158  1    43.66  ? 269 TYR A OH  1 
ATOM   4303 N  N   . ASP B 2 274 ? -5.69   -31.22  -8.566  1    39.49  ? 270 ASP A N   1 
ATOM   4304 C  CA  . ASP B 2 274 ? -6.58   -30.251 -9.185  1    43.63  ? 270 ASP A CA  1 
ATOM   4305 C  C   . ASP B 2 274 ? -7.546  -29.706 -8.136  1    42.36  ? 270 ASP A C   1 
ATOM   4306 O  O   . ASP B 2 274 ? -8.386  -30.45  -7.65   1    45.61  ? 270 ASP A O   1 
ATOM   4307 C  CB  . ASP B 2 274 ? -7.353  -30.855 -10.352 1    42.12  ? 270 ASP A CB  1 
ATOM   4308 C  CG  . ASP B 2 274 ? -8.058  -29.834 -11.235 1    46.91  ? 270 ASP A CG  1 
ATOM   4309 O  OD1 . ASP B 2 274 ? -8.167  -28.661 -10.8   1    47.72  ? 270 ASP A OD1 1 
ATOM   4310 O  OD2 . ASP B 2 274 ? -8.47   -30.207 -12.365 1    53.26  ? 270 ASP A OD2 1 
ATOM   4311 N  N   . PRO B 2 275 ? -7.484  -28.413 -7.739  1    42.54  ? 271 PRO A N   1 
ATOM   4312 C  CA  . PRO B 2 275 ? -8.434  -27.862 -6.768  1    39.88  ? 271 PRO A CA  1 
ATOM   4313 C  C   . PRO B 2 275 ? -9.889  -28.061 -7.184  1    43.38  ? 271 PRO A C   1 
ATOM   4314 O  O   . PRO B 2 275 ? -10.755 -28.132 -6.316  1    44.95  ? 271 PRO A O   1 
ATOM   4315 C  CB  . PRO B 2 275 ? -8.071  -26.366 -6.721  1    38.26  ? 271 PRO A CB  1 
ATOM   4316 C  CG  . PRO B 2 275 ? -6.635  -26.324 -7.065  1    37.32  ? 271 PRO A CG  1 
ATOM   4317 C  CD  . PRO B 2 275 ? -6.49   -27.413 -8.159  1    43.75  ? 271 PRO A CD  1 
ATOM   4318 N  N   . ASN B 2 276 ? -10.136 -28.159 -8.502  1    44.52  ? 272 ASN A N   1 
ATOM   4319 C  CA  . ASN B 2 276 ? -11.476 -28.34  -9.056  1    47.71  ? 272 ASN A CA  1 
ATOM   4320 C  C   . ASN B 2 276 ? -12.026 -29.747 -8.772  1    45     ? 272 ASN A C   1 
ATOM   4321 O  O   . ASN B 2 276 ? -13.242 -29.895 -8.636  1    43.61  ? 272 ASN A O   1 
ATOM   4322 C  CB  . ASN B 2 276 ? -11.546 -28.013 -10.549 1    45.48  ? 272 ASN A CB  1 
ATOM   4323 C  CG  . ASN B 2 276 ? -11.272 -26.561 -10.879 1    46.36  ? 272 ASN A CG  1 
ATOM   4324 O  OD1 . ASN B 2 276 ? -11.525 -25.649 -10.092 1    44.31  ? 272 ASN A OD1 1 
ATOM   4325 N  ND2 . ASN B 2 276 ? -10.759 -26.309 -12.063 1    50.76  ? 272 ASN A ND2 1 
ATOM   4326 N  N   . LYS B 2 277 ? -11.154 -30.769 -8.694  1    43     ? 273 LYS A N   1 
ATOM   4327 C  CA  . LYS B 2 277 ? -11.559 -32.16  -8.493  1    43.27  ? 273 LYS A CA  1 
ATOM   4328 C  C   . LYS B 2 277 ? -11.514 -32.52  -7.01   1    39.4   ? 273 LYS A C   1 
ATOM   4329 O  O   . LYS B 2 277 ? -12.133 -33.479 -6.571  1    38.63  ? 273 LYS A O   1 
ATOM   4330 C  CB  . LYS B 2 277 ? -10.637 -33.183 -9.173  1    47.29  ? 273 LYS A CB  1 
ATOM   4331 C  CG  . LYS B 2 277 ? -10.497 -33.101 -10.679 1    59.25  ? 273 LYS A CG  1 
ATOM   4332 C  CD  . LYS B 2 277 ? -11.841 -33.158 -11.399 1    67.74  ? 273 LYS A CD  1 
ATOM   4333 C  CE  . LYS B 2 277 ? -11.785 -32.68  -12.823 1    76.33  ? 273 LYS A CE  1 
ATOM   4334 N  NZ  . LYS B 2 277 ? -13.015 -31.95  -13.174 1    75.94  ? 273 LYS A NZ  1 
ATOM   4335 N  N   . ARG B 2 278 ? -10.735 -31.763 -6.238  1    40.58  ? 274 ARG A N   1 
ATOM   4336 C  CA  . ARG B 2 278 ? -10.609 -32.044 -4.815  1    37.5   ? 274 ARG A CA  1 
ATOM   4337 C  C   . ARG B 2 278 ? -12.004 -31.968 -4.197  1    37.71  ? 274 ARG A C   1 
ATOM   4338 O  O   . ARG B 2 278 ? -12.808 -31.094 -4.573  1    30.96  ? 274 ARG A O   1 
ATOM   4339 C  CB  . ARG B 2 278 ? -9.646  -31.026 -4.208  1    36.9   ? 274 ARG A CB  1 
ATOM   4340 C  CG  . ARG B 2 278 ? -9.058  -31.482 -2.888  1    39.76  ? 274 ARG A CG  1 
ATOM   4341 C  CD  . ARG B 2 278 ? -8.015  -30.498 -2.366  1    37.32  ? 274 ARG A CD  1 
ATOM   4342 N  NE  . ARG B 2 278 ? -6.948  -30.215 -3.33   1    39.33  ? 274 ARG A NE  1 
ATOM   4343 C  CZ  . ARG B 2 278 ? -6.297  -29.057 -3.4    1    35.26  ? 274 ARG A CZ  1 
ATOM   4344 N  NH1 . ARG B 2 278 ? -6.497  -28.127 -2.487  1    34.67  ? 274 ARG A NH1 1 
ATOM   4345 N  NH2 . ARG B 2 278 ? -5.441  -28.845 -4.376  1    33.41  ? 274 ARG A NH2 1 
ATOM   4346 N  N   . ILE B 2 279 ? -12.259 -32.899 -3.252  1    36.81  ? 275 ILE A N   1 
ATOM   4347 C  CA  . ILE B 2 279 ? -13.588 -33.115 -2.693  1    34.2   ? 275 ILE A CA  1 
ATOM   4348 C  C   . ILE B 2 279 ? -13.961 -31.91  -1.835  1    35.4   ? 275 ILE A C   1 
ATOM   4349 O  O   . ILE B 2 279 ? -13.082 -31.329 -1.211  1    40.37  ? 275 ILE A O   1 
ATOM   4350 C  CB  . ILE B 2 279 ? -13.658 -34.452 -1.921  1    33.28  ? 275 ILE A CB  1 
ATOM   4351 C  CG1 . ILE B 2 279 ? -15.093 -34.823 -1.585  1    31.86  ? 275 ILE A CG1 1 
ATOM   4352 C  CG2 . ILE B 2 279 ? -12.783 -34.479 -0.666  1    27.99  ? 275 ILE A CG2 1 
ATOM   4353 C  CD1 . ILE B 2 279 ? -15.285 -36.278 -1.243  1    29.48  ? 275 ILE A CD1 1 
ATOM   4354 N  N   . SER B 2 280 ? -15.25  -31.53  -1.803  1    35.45  ? 276 SER A N   1 
ATOM   4355 C  CA  . SER B 2 280 ? -15.705 -30.487 -0.891  1    33.16  ? 276 SER A CA  1 
ATOM   4356 C  C   . SER B 2 280 ? -15.978 -31.099 0.484   1    36.17  ? 276 SER A C   1 
ATOM   4357 O  O   . SER B 2 280 ? -16.28  -32.287 0.577   1    34.77  ? 276 SER A O   1 
ATOM   4358 C  CB  . SER B 2 280 ? -16.938 -29.807 -1.412  1    32.69  ? 276 SER A CB  1 
ATOM   4359 O  OG  . SER B 2 280 ? -18.061 -30.679 -1.421  1    32.18  ? 276 SER A OG  1 
ATOM   4360 N  N   . ALA B 2 281 ? -15.899 -30.274 1.543   1    37.01  ? 277 ALA A N   1 
ATOM   4361 C  CA  . ALA B 2 281 ? -16.303 -30.707 2.874   1    36.7   ? 277 ALA A CA  1 
ATOM   4362 C  C   . ALA B 2 281 ? -17.743 -31.247 2.881   1    38.1   ? 277 ALA A C   1 
ATOM   4363 O  O   . ALA B 2 281 ? -18.049 -32.273 3.48    1    40.22  ? 277 ALA A O   1 
ATOM   4364 C  CB  . ALA B 2 281 ? -16.131 -29.57  3.84    1    31.85  ? 277 ALA A CB  1 
ATOM   4365 N  N   . LYS B 2 282 ? -18.642 -30.563 2.191   1    38.36  ? 278 LYS A N   1 
ATOM   4366 C  CA  . LYS B 2 282 ? -20.045 -30.948 2.192   1    40.59  ? 278 LYS A CA  1 
ATOM   4367 C  C   . LYS B 2 282 ? -20.204 -32.352 1.607   1    40.88  ? 278 LYS A C   1 
ATOM   4368 O  O   . LYS B 2 282 ? -20.938 -33.167 2.15    1    44.09  ? 278 LYS A O   1 
ATOM   4369 C  CB  . LYS B 2 282 ? -20.834 -29.78  1.58    1    37.26  ? 278 LYS A CB  1 
ATOM   4370 C  CG  . LYS B 2 282 ? -22.027 -30.125 0.764   1    45.23  ? 278 LYS A CG  1 
ATOM   4371 C  CD  . LYS B 2 282 ? -22.703 -28.902 0.147   1    50.61  ? 278 LYS A CD  1 
ATOM   4372 C  CE  . LYS B 2 282 ? -22.966 -27.759 1.085   1    48.6   ? 278 LYS A CE  1 
ATOM   4373 N  NZ  . LYS B 2 282 ? -23.825 -26.758 0.446   1    47.78  ? 278 LYS A NZ  1 
ATOM   4374 N  N   . ALA B 2 283 ? -19.45  -32.675 0.556   1    42.42  ? 279 ALA A N   1 
ATOM   4375 C  CA  . ALA B 2 283 ? -19.608 -33.964 -0.124  1    43.45  ? 279 ALA A CA  1 
ATOM   4376 C  C   . ALA B 2 283 ? -18.911 -35.106 0.62    1    44.63  ? 279 ALA A C   1 
ATOM   4377 O  O   . ALA B 2 283 ? -19.387 -36.248 0.592   1    48.8   ? 279 ALA A O   1 
ATOM   4378 C  CB  . ALA B 2 283 ? -19.115 -33.88  -1.55   1    38.66  ? 279 ALA A CB  1 
ATOM   4379 N  N   . ALA B 2 284 ? -17.794 -34.767 1.285   1    39     ? 280 ALA A N   1 
ATOM   4380 C  CA  . ALA B 2 284 ? -17.014 -35.679 2.107   1    36.46  ? 280 ALA A CA  1 
ATOM   4381 C  C   . ALA B 2 284 ? -17.842 -36.225 3.269   1    39.1   ? 280 ALA A C   1 
ATOM   4382 O  O   . ALA B 2 284 ? -17.644 -37.367 3.653   1    41.6   ? 280 ALA A O   1 
ATOM   4383 C  CB  . ALA B 2 284 ? -15.779 -34.987 2.609   1    31.1   ? 280 ALA A CB  1 
ATOM   4384 N  N   . LEU B 2 285 ? -18.787 -35.436 3.8     1    36.05  ? 281 LEU A N   1 
ATOM   4385 C  CA  . LEU B 2 285 ? -19.647 -35.91  4.868   1    36.63  ? 281 LEU A CA  1 
ATOM   4386 C  C   . LEU B 2 285 ? -20.422 -37.164 4.474   1    40.41  ? 281 LEU A C   1 
ATOM   4387 O  O   . LEU B 2 285 ? -20.9   -37.876 5.35    1    45.45  ? 281 LEU A O   1 
ATOM   4388 C  CB  . LEU B 2 285 ? -20.623 -34.808 5.277   1    38.24  ? 281 LEU A CB  1 
ATOM   4389 C  CG  . LEU B 2 285 ? -20.017 -33.624 6.035   1    36.03  ? 281 LEU A CG  1 
ATOM   4390 C  CD1 . LEU B 2 285 ? -21.063 -32.577 6.264   1    34.95  ? 281 LEU A CD1 1 
ATOM   4391 C  CD2 . LEU B 2 285 ? -19.436 -34.083 7.356   1    34.67  ? 281 LEU A CD2 1 
ATOM   4392 N  N   . ALA B 2 286 ? -20.598 -37.427 3.175   1    39.66  ? 282 ALA A N   1 
ATOM   4393 C  CA  . ALA B 2 286 ? -21.398 -38.575 2.771   1    38.64  ? 282 ALA A CA  1 
ATOM   4394 C  C   . ALA B 2 286 ? -20.526 -39.78  2.382   1    40.17  ? 282 ALA A C   1 
ATOM   4395 O  O   . ALA B 2 286 ? -21.053 -40.809 1.928   1    40.79  ? 282 ALA A O   1 
ATOM   4396 C  CB  . ALA B 2 286 ? -22.254 -38.147 1.62    1    38.96  ? 282 ALA A CB  1 
ATOM   4397 N  N   . HIS B 2 287 ? -19.198 -39.64  2.528   1    36.95  ? 283 HIS A N   1 
ATOM   4398 C  CA  . HIS B 2 287 ? -18.273 -40.692 2.148   1    39.59  ? 283 HIS A CA  1 
ATOM   4399 C  C   . HIS B 2 287 ? -18.487 -41.954 2.987   1    42.05  ? 283 HIS A C   1 
ATOM   4400 O  O   . HIS B 2 287 ? -18.671 -41.873 4.203   1    44.83  ? 283 HIS A O   1 
ATOM   4401 C  CB  . HIS B 2 287 ? -16.829 -40.225 2.271   1    38.25  ? 283 HIS A CB  1 
ATOM   4402 C  CG  . HIS B 2 287 ? -15.869 -41.114 1.561   1    45.9   ? 283 HIS A CG  1 
ATOM   4403 N  ND1 . HIS B 2 287 ? -15.439 -42.327 2.074   1    45.23  ? 283 HIS A ND1 1 
ATOM   4404 C  CD2 . HIS B 2 287 ? -15.242 -40.96  0.363   1    46.03  ? 283 HIS A CD2 1 
ATOM   4405 C  CE1 . HIS B 2 287 ? -14.589 -42.886 1.212   1    45.08  ? 283 HIS A CE1 1 
ATOM   4406 N  NE2 . HIS B 2 287 ? -14.455 -42.077 0.166   1    44.23  ? 283 HIS A NE2 1 
ATOM   4407 N  N   . PRO B 2 288 ? -18.447 -43.155 2.36    1    41.53  ? 284 PRO A N   1 
ATOM   4408 C  CA  . PRO B 2 288 ? -18.539 -44.434 3.076   1    41.92  ? 284 PRO A CA  1 
ATOM   4409 C  C   . PRO B 2 288 ? -17.649 -44.609 4.3     1    42.65  ? 284 PRO A C   1 
ATOM   4410 O  O   . PRO B 2 288 ? -18.001 -45.391 5.191   1    47.2   ? 284 PRO A O   1 
ATOM   4411 C  CB  . PRO B 2 288 ? -18.214 -45.502 2.052   1    39.94  ? 284 PRO A CB  1 
ATOM   4412 C  CG  . PRO B 2 288 ? -18.394 -44.84  0.733   1    40.15  ? 284 PRO A CG  1 
ATOM   4413 C  CD  . PRO B 2 288 ? -18.266 -43.344 0.912   1    39.37  ? 284 PRO A CD  1 
ATOM   4414 N  N   . PHE B 2 289 ? -16.515 -43.888 4.338   1    40.05  ? 285 PHE A N   1 
ATOM   4415 C  CA  . PHE B 2 289 ? -15.613 -43.966 5.481   1    41.07  ? 285 PHE A CA  1 
ATOM   4416 C  C   . PHE B 2 289 ? -16.344 -43.666 6.797   1    41.94  ? 285 PHE A C   1 
ATOM   4417 O  O   . PHE B 2 289 ? -16.003 -44.246 7.835   1    43.13  ? 285 PHE A O   1 
ATOM   4418 C  CB  . PHE B 2 289 ? -14.423 -43.038 5.282   1    41.02  ? 285 PHE A CB  1 
ATOM   4419 C  CG  . PHE B 2 289 ? -13.39  -43.05  6.396   1    46.62  ? 285 PHE A CG  1 
ATOM   4420 C  CD1 . PHE B 2 289 ? -12.548 -44.152 6.568   1    44.7   ? 285 PHE A CD1 1 
ATOM   4421 C  CD2 . PHE B 2 289 ? -13.248 -41.941 7.244   1    46.32  ? 285 PHE A CD2 1 
ATOM   4422 C  CE1 . PHE B 2 289 ? -11.581 -44.14  7.55    1    42.83  ? 285 PHE A CE1 1 
ATOM   4423 C  CE2 . PHE B 2 289 ? -12.293 -41.948 8.245   1    43.18  ? 285 PHE A CE2 1 
ATOM   4424 C  CZ  . PHE B 2 289 ? -11.458 -43.042 8.387   1    44.98  ? 285 PHE A CZ  1 
ATOM   4425 N  N   . PHE B 2 290 ? -17.377 -42.81  6.742   1    39.41  ? 286 PHE A N   1 
ATOM   4426 C  CA  . PHE B 2 290 ? -18.098 -42.401 7.939   1    41.12  ? 286 PHE A CA  1 
ATOM   4427 C  C   . PHE B 2 290 ? -19.31  -43.296 8.218   1    49.61  ? 286 PHE A C   1 
ATOM   4428 O  O   . PHE B 2 290 ? -20.033 -43.036 9.179   1    49.08  ? 286 PHE A O   1 
ATOM   4429 C  CB  . PHE B 2 290 ? -18.518 -40.928 7.904   1    34.97  ? 286 PHE A CB  1 
ATOM   4430 C  CG  . PHE B 2 290 ? -17.34  -40.008 7.654   1    33.44  ? 286 PHE A CG  1 
ATOM   4431 C  CD1 . PHE B 2 290 ? -16.383 -39.822 8.635   1    32.36  ? 286 PHE A CD1 1 
ATOM   4432 C  CD2 . PHE B 2 290 ? -17.162 -39.374 6.423   1    33.12  ? 286 PHE A CD2 1 
ATOM   4433 C  CE1 . PHE B 2 290 ? -15.3   -38.99  8.407   1    32.56  ? 286 PHE A CE1 1 
ATOM   4434 C  CE2 . PHE B 2 290 ? -16.066 -38.549 6.193   1    32.05  ? 286 PHE A CE2 1 
ATOM   4435 C  CZ  . PHE B 2 290 ? -15.128 -38.359 7.19    1    32.07  ? 286 PHE A CZ  1 
ATOM   4436 N  N   . GLN B 2 291 ? -19.537 -44.34  7.408   1    53.7   ? 287 GLN A N   1 
ATOM   4437 C  CA  . GLN B 2 291 ? -20.769 -45.101 7.531   1    57.33  ? 287 GLN A CA  1 
ATOM   4438 C  C   . GLN B 2 291 ? -21.08  -45.479 8.98    1    61.16  ? 287 GLN A C   1 
ATOM   4439 O  O   . GLN B 2 291 ? -22.253 -45.547 9.327   1    77.17  ? 287 GLN A O   1 
ATOM   4440 C  CB  . GLN B 2 291 ? -20.856 -46.324 6.612   1    63.79  ? 287 GLN A CB  1 
ATOM   4441 C  CG  . GLN B 2 291 ? -19.994 -47.531 6.991   1    73.8   ? 287 GLN A CG  1 
ATOM   4442 C  CD  . GLN B 2 291 ? -19.973 -48.628 5.929   1    85.64  ? 287 GLN A CD  1 
ATOM   4443 O  OE1 . GLN B 2 291 ? -19.02  -48.78  5.141   1    81.41  ? 287 GLN A OE1 1 
ATOM   4444 N  NE2 . GLN B 2 291 ? -21.042 -49.419 5.887   1    86.51  ? 287 GLN A NE2 1 
ATOM   4445 N  N   A ASP B 2 292 ? -20.053 -45.711 9.816   0.5  60.07  ? 288 ASP A N   1 
ATOM   4446 N  N   B ASP B 2 292 ? -20.055 -45.722 9.813   0.5  61.34  ? 288 ASP A N   1 
ATOM   4447 C  CA  A ASP B 2 292 ? -20.262 -46.378 11.1    0.5  60.73  ? 288 ASP A CA  1 
ATOM   4448 C  CA  B ASP B 2 292 ? -20.267 -46.39  11.096  0.5  62.87  ? 288 ASP A CA  1 
ATOM   4449 C  C   A ASP B 2 292 ? -20.047 -45.48  12.325  0.5  61.6   ? 288 ASP A C   1 
ATOM   4450 C  C   B ASP B 2 292 ? -20.022 -45.49  12.319  0.5  62.96  ? 288 ASP A C   1 
ATOM   4451 O  O   A ASP B 2 292 ? -20.13  -45.982 13.444  0.5  64.04  ? 288 ASP A O   1 
ATOM   4452 O  O   B ASP B 2 292 ? -20.062 -45.999 13.437  0.5  65.52  ? 288 ASP A O   1 
ATOM   4453 C  CB  A ASP B 2 292 ? -19.487 -47.686 11.207  0.5  57.9   ? 288 ASP A CB  1 
ATOM   4454 C  CB  B ASP B 2 292 ? -19.58  -47.753 11.139  0.5  61.7   ? 288 ASP A CB  1 
ATOM   4455 C  CG  A ASP B 2 292 ? -18.013 -47.601 10.849  0.5  53.09  ? 288 ASP A CG  1 
ATOM   4456 C  CG  B ASP B 2 292 ? -20.363 -48.943 10.589  0.5  62.58  ? 288 ASP A CG  1 
ATOM   4457 O  OD1 A ASP B 2 292 ? -17.577 -46.513 10.425  0.5  49.82  ? 288 ASP A OD1 1 
ATOM   4458 O  OD1 B ASP B 2 292 ? -21.613 -48.873 10.558  0.5  61.85  ? 288 ASP A OD1 1 
ATOM   4459 O  OD2 A ASP B 2 292 ? -17.328 -48.628 10.973  0.5  52.85  ? 288 ASP A OD2 1 
ATOM   4460 O  OD2 B ASP B 2 292 ? -19.718 -49.938 10.186  0.5  60.55  ? 288 ASP A OD2 1 
ATOM   4461 N  N   . VAL B 2 293 ? -19.798 -44.176 12.133  1    62.36  ? 289 VAL A N   1 
ATOM   4462 C  CA  . VAL B 2 293 ? -19.728 -43.233 13.254  1    64.86  ? 289 VAL A CA  1 
ATOM   4463 C  C   . VAL B 2 293 ? -21.136 -43.054 13.802  1    72.76  ? 289 VAL A C   1 
ATOM   4464 O  O   . VAL B 2 293 ? -22.063 -42.855 13.013  1    74.57  ? 289 VAL A O   1 
ATOM   4465 C  CB  . VAL B 2 293 ? -19.154 -41.829 12.993  1    58.65  ? 289 VAL A CB  1 
ATOM   4466 C  CG1 . VAL B 2 293 ? -17.817 -41.879 12.301  1    55.09  ? 289 VAL A CG1 1 
ATOM   4467 C  CG2 . VAL B 2 293 ? -20.089 -40.963 12.174  1    57.64  ? 289 VAL A CG2 1 
ATOM   4468 N  N   . THR B 2 294 ? -21.281 -43.134 15.135  1    88.93  ? 290 THR A N   1 
ATOM   4469 C  CA  . THR B 2 294 ? -22.585 -42.963 15.775  1    99.42  ? 290 THR A CA  1 
ATOM   4470 C  C   . THR B 2 294 ? -22.425 -42.108 17.036  1    104.68 ? 290 THR A C   1 
ATOM   4471 O  O   . THR B 2 294 ? -23.385 -41.921 17.791  1    100.77 ? 290 THR A O   1 
ATOM   4472 C  CB  . THR B 2 294 ? -23.336 -44.286 16.024  1    103.82 ? 290 THR A CB  1 
ATOM   4473 O  OG1 . THR B 2 294 ? -22.56  -45.117 16.883  1    101.05 ? 290 THR A OG1 1 
ATOM   4474 C  CG2 . THR B 2 294 ? -23.691 -45.066 14.764  1    98.5   ? 290 THR A CG2 1 
ATOM   4475 N  N   . LYS B 2 295 ? -21.197 -41.592 17.243  1    114.57 ? 291 LYS A N   1 
ATOM   4476 C  CA  . LYS B 2 295 ? -20.895 -40.569 18.24   1    114.92 ? 291 LYS A CA  1 
ATOM   4477 C  C   . LYS B 2 295 ? -21.917 -39.42  18.132  1    118.44 ? 291 LYS A C   1 
ATOM   4478 O  O   . LYS B 2 295 ? -21.98  -38.77  17.091  1    112.74 ? 291 LYS A O   1 
ATOM   4479 C  CB  . LYS B 2 295 ? -19.424 -40.175 18.015  1    94.35  ? 291 LYS A CB  1 
ATOM   4480 C  CG  . LYS B 2 295 ? -18.898 -39.074 18.931  1    83.57  ? 291 LYS A CG  1 
ATOM   4481 C  CD  . LYS B 2 295 ? -18.747 -39.438 20.41   1    90.68  ? 291 LYS A CD  1 
ATOM   4482 C  CE  . LYS B 2 295 ? -19.138 -38.318 21.349  1    91.44  ? 291 LYS A CE  1 
ATOM   4483 N  NZ  . LYS B 2 295 ? -18.862 -37.005 20.75   1    85.42  ? 291 LYS A NZ  1 
ATOM   4484 N  N   . PRO B 2 296 ? -22.78  -39.131 19.15   1    117.1  ? 292 PRO A N   1 
ATOM   4485 C  CA  . PRO B 2 296 ? -23.789 -38.068 19.029  1    106.48 ? 292 PRO A CA  1 
ATOM   4486 C  C   . PRO B 2 296 ? -23.196 -36.683 18.79   1    104.26 ? 292 PRO A C   1 
ATOM   4487 O  O   . PRO B 2 296 ? -22.187 -36.32  19.4    1    108.64 ? 292 PRO A O   1 
ATOM   4488 C  CB  . PRO B 2 296 ? -24.62  -38.1   20.33   1    106.96 ? 292 PRO A CB  1 
ATOM   4489 C  CG  . PRO B 2 296 ? -24.243 -39.415 20.983  1    114.06 ? 292 PRO A CG  1 
ATOM   4490 C  CD  . PRO B 2 296 ? -22.864 -39.817 20.454  1    120.49 ? 292 PRO A CD  1 
ATOM   4491 N  N   . VAL B 2 297 ? -23.842 -35.934 17.888  1    100.75 ? 293 VAL A N   1 
ATOM   4492 C  CA  . VAL B 2 297 ? -23.455 -34.573 17.551  1    100.95 ? 293 VAL A CA  1 
ATOM   4493 C  C   . VAL B 2 297 ? -23.399 -33.738 18.833  1    97.99  ? 293 VAL A C   1 
ATOM   4494 O  O   . VAL B 2 297 ? -24.344 -33.761 19.63   1    88.06  ? 293 VAL A O   1 
ATOM   4495 C  CB  . VAL B 2 297 ? -24.329 -33.902 16.466  1    91.22  ? 293 VAL A CB  1 
ATOM   4496 C  CG1 . VAL B 2 297 ? -23.976 -32.44  16.221  1    82.87  ? 293 VAL A CG1 1 
ATOM   4497 C  CG2 . VAL B 2 297 ? -24.333 -34.686 15.168  1    93.51  ? 293 VAL A CG2 1 
ATOM   4498 N  N   . PRO B 2 298 ? -22.282 -32.996 19.067  1    97.94  ? 294 PRO A N   1 
ATOM   4499 C  CA  . PRO B 2 298 ? -22.241 -32.002 20.146  1    89.92  ? 294 PRO A CA  1 
ATOM   4500 C  C   . PRO B 2 298 ? -23.411 -31.022 19.984  1    86.85  ? 294 PRO A C   1 
ATOM   4501 O  O   . PRO B 2 298 ? -23.821 -30.689 18.865  1    78.36  ? 294 PRO A O   1 
ATOM   4502 C  CB  . PRO B 2 298 ? -20.83  -31.32  20.026  1    81.51  ? 294 PRO A CB  1 
ATOM   4503 C  CG  . PRO B 2 298 ? -20.025 -32.22  19.086  1    75.45  ? 294 PRO A CG  1 
ATOM   4504 C  CD  . PRO B 2 298 ? -21.028 -33.05  18.276  1    84.53  ? 294 PRO A CD  1 
ATOM   4505 N  N   . HIS B 2 299 ? -23.957 -30.557 21.115  1    92.27  ? 295 HIS A N   1 
ATOM   4506 C  CA  . HIS B 2 299 ? -25.017 -29.552 21.103  1    93.05  ? 295 HIS A CA  1 
ATOM   4507 C  C   . HIS B 2 299 ? -24.419 -28.17  20.816  1    89.86  ? 295 HIS A C   1 
ATOM   4508 O  O   . HIS B 2 299 ? -23.238 -27.92  21.077  1    74.73  ? 295 HIS A O   1 
ATOM   4509 C  CB  . HIS B 2 299 ? -25.85  -29.609 22.393  1    97.7   ? 295 HIS A CB  1 
ATOM   4510 C  CG  . HIS B 2 299 ? -26.904 -30.693 22.443  1    117.85 ? 295 HIS A CG  1 
ATOM   4511 N  ND1 . HIS B 2 299 ? -28.007 -30.703 21.606  1    122.18 ? 295 HIS A ND1 1 
ATOM   4512 C  CD2 . HIS B 2 299 ? -27.037 -31.792 23.226  1    114.74 ? 295 HIS A CD2 1 
ATOM   4513 C  CE1 . HIS B 2 299 ? -28.769 -31.76  21.874  1    117.78 ? 295 HIS A CE1 1 
ATOM   4514 N  NE2 . HIS B 2 299 ? -28.198 -32.432 22.857  1    117.52 ? 295 HIS A NE2 1 
ATOM   4515 N  N   . LEU B 2 300 ? -25.236 -27.269 20.254  1    90.03  ? 296 LEU A N   1 
ATOM   4516 C  CA  . LEU B 2 300 ? -24.801 -25.9   19.996  1    93.77  ? 296 LEU A CA  1 
ATOM   4517 C  C   . LEU B 2 300 ? -24.517 -25.207 21.337  1    95.23  ? 296 LEU A C   1 
ATOM   4518 O  O   . LEU B 2 300 ? -25.143 -25.538 22.349  1    96.6   ? 296 LEU A O   1 
ATOM   4519 C  CB  . LEU B 2 300 ? -25.871 -25.185 19.158  1    90.99  ? 296 LEU A CB  1 
ATOM   4520 C  CG  . LEU B 2 300 ? -25.798 -25.376 17.635  1    84.97  ? 296 LEU A CG  1 
ATOM   4521 C  CD1 . LEU B 2 300 ? -26.069 -26.814 17.182  1    77.08  ? 296 LEU A CD1 1 
ATOM   4522 C  CD2 . LEU B 2 300 ? -26.693 -24.367 16.905  1    91.98  ? 296 LEU A CD2 1 
ATOM   4523 N  N   . ARG B 2 301 ? -23.557 -24.281 21.331  1    91.86  ? 297 ARG A N   1 
ATOM   4524 C  CA  . ARG B 2 301 ? -23.243 -23.526 22.569  1    86.18  ? 297 ARG A CA  1 
ATOM   4525 C  C   . ARG B 2 301 ? -24.09  -22.246 22.584  1    79.07  ? 297 ARG A C   1 
ATOM   4526 O  O   . ARG B 2 301 ? -24.492 -21.787 21.492  1    67.81  ? 297 ARG A O   1 
ATOM   4527 C  CB  . ARG B 2 301 ? -21.738 -23.245 22.647  1    86.76  ? 297 ARG A CB  1 
ATOM   4528 C  CG  . ARG B 2 301 ? -21     -24.243 23.525  1    80.12  ? 297 ARG A CG  1 
ATOM   4529 C  CD  . ARG B 2 301 ? -21.74  -24.469 24.835  1    87.32  ? 297 ARG A CD  1 
ATOM   4530 N  NE  . ARG B 2 301 ? -21.416 -23.445 25.835  1    87.15  ? 297 ARG A NE  1 
ATOM   4531 C  CZ  . ARG B 2 301 ? -20.46  -23.566 26.748  1    86.48  ? 297 ARG A CZ  1 
ATOM   4532 N  NH1 . ARG B 2 301 ? -20.766 -23.546 28.032  1    80.14  ? 297 ARG A NH1 1 
ATOM   4533 N  NH2 . ARG B 2 301 ? -19.202 -23.709 26.375  1    78.61  ? 297 ARG A NH2 1 
ATOM   4534 N  N   . LEU B 2 302 ? -24.359 -21.706 23.773  1    77.17  ? 298 LEU A N   1 
ATOM   4535 C  CA  . LEU B 2 302 ? -25.173 -20.497 23.897  1    78.59  ? 298 LEU A CA  1 
ATOM   4536 C  C   . LEU B 2 302 ? -24.291 -19.24  23.974  1    74.83  ? 298 LEU A C   1 
ATOM   4537 O  O   . LEU B 2 302 ? -23.234 -19.365 24.627  1    77.32  ? 298 LEU A O   1 
ATOM   4538 C  CB  . LEU B 2 302 ? -26.063 -20.581 25.136  1    78.03  ? 298 LEU A CB  1 
ATOM   4539 C  CG  . LEU B 2 302 ? -27.154 -21.653 25.107  1    71.23  ? 298 LEU A CG  1 
ATOM   4540 C  CD1 . LEU B 2 302 ? -27.562 -21.964 26.515  1    65.87  ? 298 LEU A CD1 1 
ATOM   4541 C  CD2 . LEU B 2 302 ? -28.351 -21.217 24.292  1    70.5   ? 298 LEU A CD2 1 
ATOM   4542 N  N   . GLY C 1 1   ? -15.508 -23.927 -11.875 1    43.94  ? 171 GLY B N   1 
ATOM   4543 C  CA  . GLY C 1 1   ? -14.52  -24.626 -11.027 1    45.94  ? 171 GLY B CA  1 
ATOM   4544 C  C   . GLY C 1 1   ? -14.623 -24.177 -9.562  1    47.08  ? 171 GLY B C   1 
ATOM   4545 O  O   . GLY C 1 1   ? -15.472 -23.349 -9.195  1    47.89  ? 171 GLY B O   1 
ATOM   4546 N  N   . VAL C 1 2   ? -13.746 -24.724 -8.714  1    44.66  ? 172 VAL B N   1 
ATOM   4547 C  CA  . VAL C 1 2   ? -13.802 -24.414 -7.298  1    45.16  ? 172 VAL B CA  1 
ATOM   4548 C  C   . VAL C 1 2   ? -13.681 -22.903 -6.991  1    47.42  ? 172 VAL B C   1 
ATOM   4549 O  O   . VAL C 1 2   ? -14.075 -22.502 -5.882  1    47.11  ? 172 VAL B O   1 
ATOM   4550 C  CB  . VAL C 1 2   ? -12.785 -25.269 -6.518  1    45.37  ? 172 VAL B CB  1 
ATOM   4551 C  CG1 . VAL C 1 2   ? -11.362 -24.709 -6.662  1    43.64  ? 172 VAL B CG1 1 
ATOM   4552 C  CG2 . VAL C 1 2   ? -13.198 -25.401 -5.049  1    41.2   ? 172 VAL B CG2 1 
ATOM   4553 N  N   . ASN C 1 3   ? -13.159 -22.061 -7.92   1    44.48  ? 173 ASN B N   1 
ATOM   4554 C  CA  . ASN C 1 3   ? -13.073 -20.619 -7.655  1    44.62  ? 173 ASN B CA  1 
ATOM   4555 C  C   . ASN C 1 3   ? -14.461 -19.992 -7.615  1    44.66  ? 173 ASN B C   1 
ATOM   4556 O  O   . ASN C 1 3   ? -14.621 -18.9   -7.088  1    47.11  ? 173 ASN B O   1 
ATOM   4557 C  CB  . ASN C 1 3   ? -12.19  -19.841 -8.628  1    43.84  ? 173 ASN B CB  1 
ATOM   4558 C  CG  . ASN C 1 3   ? -10.759 -20.334 -8.61   1    46.8   ? 173 ASN B CG  1 
ATOM   4559 O  OD1 . ASN C 1 3   ? -10.267 -20.817 -7.579  1    44.67  ? 173 ASN B OD1 1 
ATOM   4560 N  ND2 . ASN C 1 3   ? -10.075 -20.22  -9.74   1    45.48  ? 173 ASN B ND2 1 
ATOM   4561 N  N   . GLU C 1 4   ? -15.438 -20.684 -8.212  1    47.13  ? 174 GLU B N   1 
ATOM   4562 C  CA  . GLU C 1 4   ? -16.827 -20.281 -8.211  1    47.35  ? 174 GLU B CA  1 
ATOM   4563 C  C   . GLU C 1 4   ? -17.598 -21.092 -7.174  1    47.49  ? 174 GLU B C   1 
ATOM   4564 O  O   . GLU C 1 4   ? -18.812 -21.005 -7.15   1    47.88  ? 174 GLU B O   1 
ATOM   4565 C  CB  . GLU C 1 4   ? -17.451 -20.552 -9.578  1    50.52  ? 174 GLU B CB  1 
ATOM   4566 C  CG  . GLU C 1 4   ? -16.504 -20.284 -10.742 1    57.89  ? 174 GLU B CG  1 
ATOM   4567 C  CD  . GLU C 1 4   ? -17.131 -20.244 -12.129 1    69.38  ? 174 GLU B CD  1 
ATOM   4568 O  OE1 . GLU C 1 4   ? -17.981 -21.092 -12.494 1    76.65  ? 174 GLU B OE1 1 
ATOM   4569 O  OE2 . GLU C 1 4   ? -16.713 -19.343 -12.873 1    73.38  ? 174 GLU B OE2 1 
ATOM   4570 N  N   . VAL C 1 5   ? -16.901 -21.906 -6.364  1    46.86  ? 175 VAL B N   1 
ATOM   4571 C  CA  . VAL C 1 5   ? -17.465 -22.692 -5.266  1    45.13  ? 175 VAL B CA  1 
ATOM   4572 C  C   . VAL C 1 5   ? -18.824 -23.283 -5.631  1    47.29  ? 175 VAL B C   1 
ATOM   4573 O  O   . VAL C 1 5   ? -19.836 -22.961 -5.003  1    48.34  ? 175 VAL B O   1 
ATOM   4574 C  CB  . VAL C 1 5   ? -17.538 -21.943 -3.919  1    38.95  ? 175 VAL B CB  1 
ATOM   4575 C  CG1 . VAL C 1 5   ? -16.143 -21.741 -3.344  1    37.53  ? 175 VAL B CG1 1 
ATOM   4576 C  CG2 . VAL C 1 5   ? -18.317 -20.641 -4.015  1    34.27  ? 175 VAL B CG2 1 
ATOM   4577 N  N   . PRO C 1 6   ? -18.896 -24.171 -6.644  1    50.64  ? 176 PRO B N   1 
ATOM   4578 C  CA  . PRO C 1 6   ? -20.166 -24.775 -7.058  1    48.47  ? 176 PRO B CA  1 
ATOM   4579 C  C   . PRO C 1 6   ? -20.972 -25.364 -5.896  1    50.29  ? 176 PRO B C   1 
ATOM   4580 O  O   . PRO C 1 6   ? -22.202 -25.355 -5.934  1    51.24  ? 176 PRO B O   1 
ATOM   4581 C  CB  . PRO C 1 6   ? -19.754 -25.885 -8.074  1    46.76  ? 176 PRO B CB  1 
ATOM   4582 C  CG  . PRO C 1 6   ? -18.245 -26.005 -7.998  1    44.42  ? 176 PRO B CG  1 
ATOM   4583 C  CD  . PRO C 1 6   ? -17.75  -24.687 -7.414  1    49.4   ? 176 PRO B CD  1 
ATOM   4584 N  N   . ASP C 1 7   ? -20.261 -25.879 -4.875  1    52.09  ? 177 ASP B N   1 
ATOM   4585 C  CA  . ASP C 1 7   ? -20.855 -26.633 -3.786  1    49.2   ? 177 ASP B CA  1 
ATOM   4586 C  C   . ASP C 1 7   ? -21.405 -25.718 -2.687  1    47.43  ? 177 ASP B C   1 
ATOM   4587 O  O   . ASP C 1 7   ? -22.097 -26.202 -1.796  1    50.84  ? 177 ASP B O   1 
ATOM   4588 C  CB  . ASP C 1 7   ? -19.895 -27.689 -3.267  1    50.76  ? 177 ASP B CB  1 
ATOM   4589 C  CG  . ASP C 1 7   ? -19.988 -29.03  -3.974  1    54.94  ? 177 ASP B CG  1 
ATOM   4590 O  OD1 . ASP C 1 7   ? -20.656 -29.069 -5.022  1    57.89  ? 177 ASP B OD1 1 
ATOM   4591 O  OD2 . ASP C 1 7   ? -19.433 -30.037 -3.45   1    53.96  ? 177 ASP B OD2 1 
ATOM   4592 N  N   . TYR C 1 8   ? -21.117 -24.407 -2.751  1    40.74  ? 178 TYR B N   1 
ATOM   4593 C  CA  . TYR C 1 8   ? -21.442 -23.513 -1.651  1    39.43  ? 178 TYR B CA  1 
ATOM   4594 C  C   . TYR C 1 8   ? -22.095 -22.213 -2.126  1    38.46  ? 178 TYR B C   1 
ATOM   4595 O  O   . TYR C 1 8   ? -22.475 -21.404 -1.289  1    36.83  ? 178 TYR B O   1 
ATOM   4596 C  CB  . TYR C 1 8   ? -20.255 -23.184 -0.729  1    36.9   ? 178 TYR B CB  1 
ATOM   4597 C  CG  . TYR C 1 8   ? -19.606 -24.394 -0.095  1    38.75  ? 178 TYR B CG  1 
ATOM   4598 C  CD1 . TYR C 1 8   ? -20.131 -24.953 1.058   1    41.85  ? 178 TYR B CD1 1 
ATOM   4599 C  CD2 . TYR C 1 8   ? -18.499 -25.01  -0.671  1    39.21  ? 178 TYR B CD2 1 
ATOM   4600 C  CE1 . TYR C 1 8   ? -19.541 -26.063 1.649   1    41.14  ? 178 TYR B CE1 1 
ATOM   4601 C  CE2 . TYR C 1 8   ? -17.907 -26.128 -0.099  1    40.17  ? 178 TYR B CE2 1 
ATOM   4602 C  CZ  . TYR C 1 8   ? -18.426 -26.653 1.073   1    40.83  ? 178 TYR B CZ  1 
ATOM   4603 O  OH  . TYR C 1 8   ? -17.876 -27.783 1.617   1    40.8   ? 178 TYR B OH  1 
ATOM   4604 N  N   . HIS C 1 9   ? -22.247 -21.989 -3.437  1    40.34  ? 179 HIS B N   1 
ATOM   4605 C  CA  . HIS C 1 9   ? -22.626 -20.65  -3.891  1    44.42  ? 179 HIS B CA  1 
ATOM   4606 C  C   . HIS C 1 9   ? -24.083 -20.3   -3.554  1    41.15  ? 179 HIS B C   1 
ATOM   4607 O  O   . HIS C 1 9   ? -24.391 -19.137 -3.308  1    41.86  ? 179 HIS B O   1 
ATOM   4608 C  CB  . HIS C 1 9   ? -22.158 -20.398 -5.335  1    52.34  ? 179 HIS B CB  1 
ATOM   4609 C  CG  . HIS C 1 9   ? -23.112 -20.874 -6.363  1    64.65  ? 179 HIS B CG  1 
ATOM   4610 N  ND1 . HIS C 1 9   ? -23.8   -19.993 -7.172  1    68.3   ? 179 HIS B ND1 1 
ATOM   4611 C  CD2 . HIS C 1 9   ? -23.523 -22.125 -6.688  1    68.15  ? 179 HIS B CD2 1 
ATOM   4612 C  CE1 . HIS C 1 9   ? -24.615 -20.703 -7.951  1    81.97  ? 179 HIS B CE1 1 
ATOM   4613 N  NE2 . HIS C 1 9   ? -24.472 -21.997 -7.668  1    72.62  ? 179 HIS B NE2 1 
ATOM   4614 N  N   . GLU C 1 10  ? -24.978 -21.302 -3.57   1    43.27  ? 180 GLU B N   1 
ATOM   4615 C  CA  . GLU C 1 10  ? -26.387 -21.134 -3.253  1    44.93  ? 180 GLU B CA  1 
ATOM   4616 C  C   . GLU C 1 10  ? -26.553 -20.834 -1.766  1    44.86  ? 180 GLU B C   1 
ATOM   4617 O  O   . GLU C 1 10  ? -27.235 -19.858 -1.41   1    42.73  ? 180 GLU B O   1 
ATOM   4618 C  CB  . GLU C 1 10  ? -27.215 -22.378 -3.53   1    51.68  ? 180 GLU B CB  1 
ATOM   4619 C  CG  . GLU C 1 10  ? -27.882 -22.403 -4.896  1    66.95  ? 180 GLU B CG  1 
ATOM   4620 C  CD  . GLU C 1 10  ? -28.91  -23.538 -4.959  1    86.17  ? 180 GLU B CD  1 
ATOM   4621 O  OE1 . GLU C 1 10  ? -29.771 -23.712 -4.046  1    78.52  ? 180 GLU B OE1 1 
ATOM   4622 O  OE2 . GLU C 1 10  ? -28.859 -24.272 -5.973  1    90.84  ? 180 GLU B OE2 1 
ATOM   4623 N  N   . ASP C 1 11  ? -25.916 -21.668 -0.914  1    39.93  ? 181 ASP B N   1 
ATOM   4624 C  CA  . ASP C 1 11  ? -25.894 -21.425 0.522   1    38.2   ? 181 ASP B CA  1 
ATOM   4625 C  C   . ASP C 1 11  ? -25.365 -20.022 0.792   1    39.19  ? 181 ASP B C   1 
ATOM   4626 O  O   . ASP C 1 11  ? -25.907 -19.322 1.639   1    41.8   ? 181 ASP B O   1 
ATOM   4627 C  CB  . ASP C 1 11  ? -25.007 -22.398 1.281   1    38.89  ? 181 ASP B CB  1 
ATOM   4628 C  CG  . ASP C 1 11  ? -25.468 -23.846 1.402   1    42.35  ? 181 ASP B CG  1 
ATOM   4629 O  OD1 . ASP C 1 11  ? -26.669 -24.123 1.117   1    44.67  ? 181 ASP B OD1 1 
ATOM   4630 O  OD2 . ASP C 1 11  ? -24.614 -24.692 1.776   1    41.53  ? 181 ASP B OD2 1 
ATOM   4631 N  N   . ILE C 1 12  ? -24.293 -19.633 0.081   1    37.76  ? 182 ILE B N   1 
ATOM   4632 C  CA  . ILE C 1 12  ? -23.653 -18.352 0.282   1    36.72  ? 182 ILE B CA  1 
ATOM   4633 C  C   . ILE C 1 12  ? -24.625 -17.251 -0.118  1    37.8   ? 182 ILE B C   1 
ATOM   4634 O  O   . ILE C 1 12  ? -24.784 -16.281 0.613   1    39.33  ? 182 ILE B O   1 
ATOM   4635 C  CB  . ILE C 1 12  ? -22.288 -18.271 -0.428  1    36.62  ? 182 ILE B CB  1 
ATOM   4636 C  CG1 . ILE C 1 12  ? -21.239 -19.117 0.299   1    38.65  ? 182 ILE B CG1 1 
ATOM   4637 C  CG2 . ILE C 1 12  ? -21.782 -16.836 -0.541  1    34.22  ? 182 ILE B CG2 1 
ATOM   4638 C  CD1 . ILE C 1 12  ? -19.957 -19.339 -0.497  1    36.35  ? 182 ILE B CD1 1 
ATOM   4639 N  N   . HIS C 1 13  ? -25.26  -17.394 -1.283  1    41.16  ? 183 HIS B N   1 
ATOM   4640 C  CA  . HIS C 1 13  ? -26.281 -16.44  -1.722  1    40.44  ? 183 HIS B CA  1 
ATOM   4641 C  C   . HIS C 1 13  ? -27.405 -16.252 -0.681  1    39.7   ? 183 HIS B C   1 
ATOM   4642 O  O   . HIS C 1 13  ? -27.821 -15.136 -0.388  1    39.86  ? 183 HIS B O   1 
ATOM   4643 C  CB  . HIS C 1 13  ? -26.867 -16.88  -3.071  1    37.37  ? 183 HIS B CB  1 
ATOM   4644 C  CG  . HIS C 1 13  ? -27.899 -15.923 -3.565  1    35.61  ? 183 HIS B CG  1 
ATOM   4645 N  ND1 . HIS C 1 13  ? -27.519 -14.669 -4.013  1    36.64  ? 183 HIS B ND1 1 
ATOM   4646 C  CD2 . HIS C 1 13  ? -29.233 -15.96  -3.627  1    34.62  ? 183 HIS B CD2 1 
ATOM   4647 C  CE1 . HIS C 1 13  ? -28.585 -13.968 -4.357  1    35.55  ? 183 HIS B CE1 1 
ATOM   4648 N  NE2 . HIS C 1 13  ? -29.638 -14.736 -4.13   1    36.5   ? 183 HIS B NE2 1 
ATOM   4649 N  N   . THR C 1 14  ? -27.931 -17.358 -0.14   1    39.26  ? 184 THR B N   1 
ATOM   4650 C  CA  . THR C 1 14  ? -29.019 -17.324 0.823   1    39.72  ? 184 THR B CA  1 
ATOM   4651 C  C   . THR C 1 14  ? -28.602 -16.577 2.087   1    41.14  ? 184 THR B C   1 
ATOM   4652 O  O   . THR C 1 14  ? -29.378 -15.817 2.648   1    46.54  ? 184 THR B O   1 
ATOM   4653 C  CB  . THR C 1 14  ? -29.433 -18.754 1.145   1    37.49  ? 184 THR B CB  1 
ATOM   4654 O  OG1 . THR C 1 14  ? -30.104 -19.101 -0.057  1    39.15  ? 184 THR B OG1 1 
ATOM   4655 C  CG2 . THR C 1 14  ? -30.379 -18.826 2.326   1    35.19  ? 184 THR B CG2 1 
ATOM   4656 N  N   . TYR C 1 15  ? -27.363 -16.804 2.516   1    40.82  ? 185 TYR B N   1 
ATOM   4657 C  CA  . TYR C 1 15  ? -26.79  -16.158 3.683   1    39.6   ? 185 TYR B CA  1 
ATOM   4658 C  C   . TYR C 1 15  ? -26.56  -14.669 3.431   1    40.11  ? 185 TYR B C   1 
ATOM   4659 O  O   . TYR C 1 15  ? -26.795 -13.853 4.325   1    44.3   ? 185 TYR B O   1 
ATOM   4660 C  CB  . TYR C 1 15  ? -25.504 -16.899 4.043   1    39.68  ? 185 TYR B CB  1 
ATOM   4661 C  CG  . TYR C 1 15  ? -24.835 -16.27  5.243   1    40.56  ? 185 TYR B CG  1 
ATOM   4662 C  CD1 . TYR C 1 15  ? -25.437 -16.353 6.494   1    42.72  ? 185 TYR B CD1 1 
ATOM   4663 C  CD2 . TYR C 1 15  ? -23.625 -15.597 5.115   1    38.71  ? 185 TYR B CD2 1 
ATOM   4664 C  CE1 . TYR C 1 15  ? -24.87  -15.738 7.595   1    42.92  ? 185 TYR B CE1 1 
ATOM   4665 C  CE2 . TYR C 1 15  ? -23.018 -15.032 6.22    1    43.65  ? 185 TYR B CE2 1 
ATOM   4666 C  CZ  . TYR C 1 15  ? -23.645 -15.103 7.457   1    48.59  ? 185 TYR B CZ  1 
ATOM   4667 O  OH  . TYR C 1 15  ? -23.064 -14.538 8.552   1    57.32  ? 185 TYR B OH  1 
ATOM   4668 N  N   . LEU C 1 16  ? -26.106 -14.29  2.249   1    37.29  ? 186 LEU B N   1 
ATOM   4669 C  CA  . LEU C 1 16  ? -25.916 -12.851 1.975   1    35.24  ? 186 LEU B CA  1 
ATOM   4670 C  C   . LEU C 1 16  ? -27.276 -12.148 1.943   1    37.89  ? 186 LEU B C   1 
ATOM   4671 O  O   . LEU C 1 16  ? -27.369 -11.019 2.435   1    39.23  ? 186 LEU B O   1 
ATOM   4672 C  CB  . LEU C 1 16  ? -25.14  -12.692 0.672   1    39.02  ? 186 LEU B CB  1 
ATOM   4673 C  CG  . LEU C 1 16  ? -23.688 -13.174 0.678   1    38.16  ? 186 LEU B CG  1 
ATOM   4674 C  CD1 . LEU C 1 16  ? -23.072 -12.847 -0.664  1    34.98  ? 186 LEU B CD1 1 
ATOM   4675 C  CD2 . LEU C 1 16  ? -22.908 -12.527 1.803   1    33.09  ? 186 LEU B CD2 1 
ATOM   4676 N  N   . ARG C 1 17  ? -28.288 -12.81  1.4     1    38.32  ? 187 ARG B N   1 
ATOM   4677 C  CA  . ARG C 1 17  ? -29.644 -12.222 1.306   1    39.18  ? 187 ARG B CA  1 
ATOM   4678 C  C   . ARG C 1 17  ? -30.197 -11.965 2.713   1    43.33  ? 187 ARG B C   1 
ATOM   4679 O  O   . ARG C 1 17  ? -30.894 -10.958 2.894   1    48.94  ? 187 ARG B O   1 
ATOM   4680 C  CB  . ARG C 1 17  ? -30.517 -13.158 0.468   1    38.88  ? 187 ARG B CB  1 
ATOM   4681 C  CG  . ARG C 1 17  ? -30.231 -13.112 -1.024  1    38.22  ? 187 ARG B CG  1 
ATOM   4682 C  CD  . ARG C 1 17  ? -30.72  -11.828 -1.654  1    36.18  ? 187 ARG B CD  1 
ATOM   4683 N  NE  . ARG C 1 17  ? -32.172 -11.668 -1.535  1    35.65  ? 187 ARG B NE  1 
ATOM   4684 C  CZ  . ARG C 1 17  ? -33.064 -12.19  -2.362  1    38.76  ? 187 ARG B CZ  1 
ATOM   4685 N  NH1 . ARG C 1 17  ? -32.714 -12.54  -3.583  1    39.13  ? 187 ARG B NH1 1 
ATOM   4686 N  NH2 . ARG C 1 17  ? -34.308 -12.356 -1.964  1    36.57  ? 187 ARG B NH2 1 
ATOM   4687 N  N   . GLU C 1 18  ? -29.895 -12.841 3.662   1    42.59  ? 188 GLU B N   1 
ATOM   4688 C  CA  . GLU C 1 18  ? -30.335 -12.652 5.063   1    44.32  ? 188 GLU B CA  1 
ATOM   4689 C  C   . GLU C 1 18  ? -29.492 -11.556 5.722   1    44.89  ? 188 GLU B C   1 
ATOM   4690 O  O   . GLU C 1 18  ? -30.066 -10.706 6.412   1    45.61  ? 188 GLU B O   1 
ATOM   4691 C  CB  . GLU C 1 18  ? -30.206 -13.992 5.78    1    48.12  ? 188 GLU B CB  1 
ATOM   4692 C  CG  . GLU C 1 18  ? -30.396 -13.918 7.29    1    56.82  ? 188 GLU B CG  1 
ATOM   4693 C  CD  . GLU C 1 18  ? -30.024 -15.232 7.949   1    69.45  ? 188 GLU B CD  1 
ATOM   4694 O  OE1 . GLU C 1 18  ? -29.668 -16.171 7.208   1    67.73  ? 188 GLU B OE1 1 
ATOM   4695 O  OE2 . GLU C 1 18  ? -30.089 -15.319 9.191   1    63.62  ? 188 GLU B OE2 1 
ATOM   4696 N  N   . MET C 1 19  ? -28.178 -11.585 5.515   1    41.83  ? 189 MET B N   1 
ATOM   4697 C  CA  . MET C 1 19  ? -27.35  -10.584 6.17    1    44.41  ? 189 MET B CA  1 
ATOM   4698 C  C   . MET C 1 19  ? -27.649 -9.18   5.647   1    45.06  ? 189 MET B C   1 
ATOM   4699 O  O   . MET C 1 19  ? -27.668 -8.235  6.429   1    48.52  ? 189 MET B O   1 
ATOM   4700 C  CB  . MET C 1 19  ? -25.857 -10.872 6.023   1    36.59  ? 189 MET B CB  1 
ATOM   4701 C  CG  . MET C 1 19  ? -25.393 -12.086 6.764   1    42.3   ? 189 MET B CG  1 
ATOM   4702 S  SD  . MET C 1 19  ? -25.642 -12.043 8.552   1    54.58  ? 189 MET B SD  1 
ATOM   4703 C  CE  . MET C 1 19  ? -27.165 -12.958 8.82    1    45.05  ? 189 MET B CE  1 
ATOM   4704 N  N   . GLU C 1 20  ? -27.876 -9.033  4.341   1    39.67  ? 190 GLU B N   1 
ATOM   4705 C  CA  . GLU C 1 20  ? -28.082 -7.696  3.805   1    40.06  ? 190 GLU B CA  1 
ATOM   4706 C  C   . GLU C 1 20  ? -29.255 -6.994  4.486   1    40.77  ? 190 GLU B C   1 
ATOM   4707 O  O   . GLU C 1 20  ? -29.228 -5.777  4.586   1    43.26  ? 190 GLU B O   1 
ATOM   4708 C  CB  . GLU C 1 20  ? -28.214 -7.586  2.286   1    35.67  ? 190 GLU B CB  1 
ATOM   4709 C  CG  . GLU C 1 20  ? -29.46  -8.242  1.717   1    35.7   ? 190 GLU B CG  1 
ATOM   4710 C  CD  . GLU C 1 20  ? -29.599 -7.932  0.24    1    37.5   ? 190 GLU B CD  1 
ATOM   4711 O  OE1 . GLU C 1 20  ? -28.711 -7.212  -0.274  1    33.74  ? 190 GLU B OE1 1 
ATOM   4712 O  OE2 . GLU C 1 20  ? -30.583 -8.402  -0.394  1    34.35  ? 190 GLU B OE2 1 
ATOM   4713 N  N   . VAL C 1 21  ? -30.259 -7.755  4.942   1    39.28  ? 191 VAL B N   1 
ATOM   4714 C  CA  . VAL C 1 21  ? -31.344 -7.235  5.752   1    40.53  ? 191 VAL B CA  1 
ATOM   4715 C  C   . VAL C 1 21  ? -30.844 -6.865  7.153   1    45.31  ? 191 VAL B C   1 
ATOM   4716 O  O   . VAL C 1 21  ? -31.186 -5.814  7.668   1    49.86  ? 191 VAL B O   1 
ATOM   4717 C  CB  . VAL C 1 21  ? -32.537 -8.218  5.797   1    40.58  ? 191 VAL B CB  1 
ATOM   4718 C  CG1 . VAL C 1 21  ? -33.656 -7.747  6.724   1    34.02  ? 191 VAL B CG1 1 
ATOM   4719 C  CG2 . VAL C 1 21  ? -33.098 -8.499  4.399   1    38.13  ? 191 VAL B CG2 1 
ATOM   4720 N  N   . LYS C 1 22  ? -30.055 -7.731  7.795   1    52.48  ? 192 LYS B N   1 
ATOM   4721 C  CA  . LYS C 1 22  ? -29.487 -7.451  9.104   1    52.04  ? 192 LYS B CA  1 
ATOM   4722 C  C   . LYS C 1 22  ? -28.641 -6.168  9.062   1    53.78  ? 192 LYS B C   1 
ATOM   4723 O  O   . LYS C 1 22  ? -28.681 -5.386  9.998   1    55.9   ? 192 LYS B O   1 
ATOM   4724 C  CB  . LYS C 1 22  ? -28.682 -8.682  9.54    1    59.66  ? 192 LYS B CB  1 
ATOM   4725 C  CG  . LYS C 1 22  ? -28.049 -8.634  10.932  1    69.94  ? 192 LYS B CG  1 
ATOM   4726 C  CD  . LYS C 1 22  ? -27.301 -9.914  11.321  1    75.9   ? 192 LYS B CD  1 
ATOM   4727 C  CE  . LYS C 1 22  ? -26.632 -9.919  12.681  1    84.49  ? 192 LYS B CE  1 
ATOM   4728 N  NZ  . LYS C 1 22  ? -25.92  -11.16  13.032  1    71.14  ? 192 LYS B NZ  1 
ATOM   4729 N  N   . CYS C 1 23  ? -27.899 -5.938  7.972   1    51.76  ? 193 CYS B N   1 
ATOM   4730 C  CA  . CYS C 1 23  ? -26.905 -4.877  7.845   1    53.38  ? 193 CYS B CA  1 
ATOM   4731 C  C   . CYS C 1 23  ? -27.466 -3.627  7.149   1    54.35  ? 193 CYS B C   1 
ATOM   4732 O  O   . CYS C 1 23  ? -26.695 -2.758  6.719   1    54.5   ? 193 CYS B O   1 
ATOM   4733 C  CB  . CYS C 1 23  ? -25.685 -5.346  7.031   1    52.61  ? 193 CYS B CB  1 
ATOM   4734 S  SG  . CYS C 1 23  ? -24.489 -6.443  7.875   1    58.27  ? 193 CYS B SG  1 
ATOM   4735 N  N   . LYS C 1 24  ? -28.794 -3.527  6.992   1    49.04  ? 194 LYS B N   1 
ATOM   4736 C  CA  . LYS C 1 24  ? -29.342 -2.426  6.212   1    46.67  ? 194 LYS B CA  1 
ATOM   4737 C  C   . LYS C 1 24  ? -29.373 -1.138  7.05    1    51     ? 194 LYS B C   1 
ATOM   4738 O  O   . LYS C 1 24  ? -29.776 -1.161  8.208   1    49.29  ? 194 LYS B O   1 
ATOM   4739 C  CB  . LYS C 1 24  ? -30.754 -2.769  5.735   1    49.29  ? 194 LYS B CB  1 
ATOM   4740 C  CG  . LYS C 1 24  ? -31.292 -1.781  4.733   1    57.17  ? 194 LYS B CG  1 
ATOM   4741 C  CD  . LYS C 1 24  ? -32.755 -1.985  4.359   1    63.57  ? 194 LYS B CD  1 
ATOM   4742 C  CE  . LYS C 1 24  ? -33.125 -1.11   3.178   1    63.79  ? 194 LYS B CE  1 
ATOM   4743 N  NZ  . LYS C 1 24  ? -34.541 -1.239  2.817   1    68.23  ? 194 LYS B NZ  1 
ATOM   4744 N  N   . PRO C 1 25  ? -28.996 0.049   6.504   1    52.39  ? 195 PRO B N   1 
ATOM   4745 C  CA  . PRO C 1 25  ? -29.109 1.307   7.253   1    49.03  ? 195 PRO B CA  1 
ATOM   4746 C  C   . PRO C 1 25  ? -30.588 1.646   7.391   1    46.32  ? 195 PRO B C   1 
ATOM   4747 O  O   . PRO C 1 25  ? -31.377 1.081   6.654   1    52.99  ? 195 PRO B O   1 
ATOM   4748 C  CB  . PRO C 1 25  ? -28.379 2.348   6.338   1    53.83  ? 195 PRO B CB  1 
ATOM   4749 C  CG  . PRO C 1 25  ? -27.611 1.525   5.301   1    48.74  ? 195 PRO B CG  1 
ATOM   4750 C  CD  . PRO C 1 25  ? -28.43  0.249   5.152   1    49.9   ? 195 PRO B CD  1 
ATOM   4751 N  N   . LYS C 1 26  ? -30.946 2.56    8.304   1    46.28  ? 196 LYS B N   1 
ATOM   4752 C  CA  . LYS C 1 26  ? -32.273 3.171   8.321   1    51.05  ? 196 LYS B CA  1 
ATOM   4753 C  C   . LYS C 1 26  ? -32.472 3.959   7.029   1    56.14  ? 196 LYS B C   1 
ATOM   4754 O  O   . LYS C 1 26  ? -31.606 4.74    6.655   1    56.34  ? 196 LYS B O   1 
ATOM   4755 C  CB  . LYS C 1 26  ? -32.478 4.206   9.431   1    53.78  ? 196 LYS B CB  1 
ATOM   4756 C  CG  . LYS C 1 26  ? -32.625 3.693   10.862  1    64.55  ? 196 LYS B CG  1 
ATOM   4757 C  CD  . LYS C 1 26  ? -32.977 4.758   11.907  1    74.22  ? 196 LYS B CD  1 
ATOM   4758 C  CE  . LYS C 1 26  ? -32.948 4.152   13.3    1    79.56  ? 196 LYS B CE  1 
ATOM   4759 N  NZ  . LYS C 1 26  ? -33.075 5.089   14.425  1    71.02  ? 196 LYS B NZ  1 
ATOM   4760 N  N   . VAL C 1 27  ? -33.608 3.736   6.355   1    57.58  ? 197 VAL B N   1 
ATOM   4761 C  CA  . VAL C 1 27  ? -33.948 4.398   5.103   1    55.57  ? 197 VAL B CA  1 
ATOM   4762 C  C   . VAL C 1 27  ? -34.021 5.911   5.304   1    56.7   ? 197 VAL B C   1 
ATOM   4763 O  O   . VAL C 1 27  ? -33.657 6.67    4.409   1    58.4   ? 197 VAL B O   1 
ATOM   4764 C  CB  . VAL C 1 27  ? -35.273 3.878   4.507   1    62.18  ? 197 VAL B CB  1 
ATOM   4765 C  CG1 . VAL C 1 27  ? -35.635 4.566   3.189   1    56.28  ? 197 VAL B CG1 1 
ATOM   4766 C  CG2 . VAL C 1 27  ? -35.264 2.358   4.348   1    69.41  ? 197 VAL B CG2 1 
ATOM   4767 N  N   . GLY C 1 28  ? -34.497 6.367   6.465   1    54.04  ? 198 GLY B N   1 
ATOM   4768 C  CA  . GLY C 1 28  ? -34.812 7.786   6.553   1    63.84  ? 198 GLY B CA  1 
ATOM   4769 C  C   . GLY C 1 28  ? -33.845 8.609   7.403   1    69.32  ? 198 GLY B C   1 
ATOM   4770 O  O   . GLY C 1 28  ? -34.248 9.633   7.95    1    77.75  ? 198 GLY B O   1 
ATOM   4771 N  N   . TYR C 1 29  ? -32.571 8.2     7.468   1    62.78  ? 199 TYR B N   1 
ATOM   4772 C  CA  . TYR C 1 29  ? -31.737 8.57    8.6     1    56.21  ? 199 TYR B CA  1 
ATOM   4773 C  C   . TYR C 1 29  ? -31.354 10.042  8.521   1    55.08  ? 199 TYR B C   1 
ATOM   4774 O  O   . TYR C 1 29  ? -31.161 10.672  9.557   1    53.15  ? 199 TYR B O   1 
ATOM   4775 C  CB  . TYR C 1 29  ? -30.55  7.626   8.835   1    50.23  ? 199 TYR B CB  1 
ATOM   4776 C  CG  . TYR C 1 29  ? -29.329 7.819   7.951   1    41.46  ? 199 TYR B CG  1 
ATOM   4777 C  CD1 . TYR C 1 29  ? -28.568 8.975   8.008   1    42.44  ? 199 TYR B CD1 1 
ATOM   4778 C  CD2 . TYR C 1 29  ? -28.907 6.817   7.098   1    39.83  ? 199 TYR B CD2 1 
ATOM   4779 C  CE1 . TYR C 1 29  ? -27.443 9.151   7.214   1    42.77  ? 199 TYR B CE1 1 
ATOM   4780 C  CE2 . TYR C 1 29  ? -27.789 6.97    6.296   1    42.09  ? 199 TYR B CE2 1 
ATOM   4781 C  CZ  . TYR C 1 29  ? -27.039 8.133   6.359   1    45.87  ? 199 TYR B CZ  1 
ATOM   4782 O  OH  . TYR C 1 29  ? -25.93  8.24    5.554   1    44.58  ? 199 TYR B OH  1 
ATOM   4783 N  N   . MET C 1 30  ? -31.278 10.57   7.292   1    52.69  ? 200 MET B N   1 
ATOM   4784 C  CA  . MET C 1 30  ? -30.707 11.886  7.052   1    53.8   ? 200 MET B CA  1 
ATOM   4785 C  C   . MET C 1 30  ? -31.624 13.011  7.537   1    60.39  ? 200 MET B C   1 
ATOM   4786 O  O   . MET C 1 30  ? -31.164 14.111  7.852   1    63.23  ? 200 MET B O   1 
ATOM   4787 C  CB  . MET C 1 30  ? -30.427 12.083  5.565   1    51.27  ? 200 MET B CB  1 
ATOM   4788 C  CG  . MET C 1 30  ? -29.465 13.224  5.293   1    49.59  ? 200 MET B CG  1 
ATOM   4789 S  SD  . MET C 1 30  ? -27.815 13.017  5.989   1    52.48  ? 200 MET B SD  1 
ATOM   4790 C  CE  . MET C 1 30  ? -27.11  11.823  4.85    1    52.98  ? 200 MET B CE  1 
ATOM   4791 N  N   . LYS C 1 31  ? -32.92  12.742  7.6     1    66.39  ? 201 LYS B N   1 
ATOM   4792 C  CA  . LYS C 1 31  ? -33.868 13.751  8.125   1    65.61  ? 201 LYS B CA  1 
ATOM   4793 C  C   . LYS C 1 31  ? -33.598 13.946  9.616   1    64.58  ? 201 LYS B C   1 
ATOM   4794 O  O   . LYS C 1 31  ? -33.762 15.077  10.102  1    68.81  ? 201 LYS B O   1 
ATOM   4795 C  CB  . LYS C 1 31  ? -35.292 13.255  7.886   1    73.06  ? 201 LYS B CB  1 
ATOM   4796 C  CG  . LYS C 1 31  ? -35.543 12.74   6.479   1    87.87  ? 201 LYS B CG  1 
ATOM   4797 C  CD  . LYS C 1 31  ? -36.734 11.796  6.385   1    101.51 ? 201 LYS B CD  1 
ATOM   4798 C  CE  . LYS C 1 31  ? -37.077 11.452  4.971   1    105.4  ? 201 LYS B CE  1 
ATOM   4799 N  NZ  . LYS C 1 31  ? -38.175 12.277  4.464   1    97.36  ? 201 LYS B NZ  1 
ATOM   4800 N  N   . LYS C 1 32  ? -33.176 12.887  10.299  1    64.21  ? 202 LYS B N   1 
ATOM   4801 C  CA  . LYS C 1 32  ? -32.917 12.96   11.757  1    64.68  ? 202 LYS B CA  1 
ATOM   4802 C  C   . LYS C 1 32  ? -31.487 13.441  11.994  1    64.52  ? 202 LYS B C   1 
ATOM   4803 O  O   . LYS C 1 32  ? -31.067 13.466  13.161  1    65.89  ? 202 LYS B O   1 
ATOM   4804 C  CB  . LYS C 1 32  ? -33.143 11.59   12.392  1    66.26  ? 202 LYS B CB  1 
ATOM   4805 C  CG  . LYS C 1 32  ? -34.588 11.126  12.368  1    73.56  ? 202 LYS B CG  1 
ATOM   4806 C  CD  . LYS C 1 32  ? -34.812 9.805   13.09   1    74.48  ? 202 LYS B CD  1 
ATOM   4807 C  CE  . LYS C 1 32  ? -36.258 9.434   13.154  1    70.26  ? 202 LYS B CE  1 
ATOM   4808 N  NZ  . LYS C 1 32  ? -36.777 9.04    11.843  1    69.82  ? 202 LYS B NZ  1 
ATOM   4809 N  N   . GLN C 1 33  ? -30.766 13.787  10.929  1    58.95  ? 203 GLN B N   1 
ATOM   4810 C  CA  . GLN C 1 33  ? -29.407 14.358  11.094  1    54.65  ? 203 GLN B CA  1 
ATOM   4811 C  C   . GLN C 1 33  ? -29.564 15.879  11.015  1    53.51  ? 203 GLN B C   1 
ATOM   4812 O  O   . GLN C 1 33  ? -29.78  16.396  9.914   1    58.85  ? 203 GLN B O   1 
ATOM   4813 C  CB  . GLN C 1 33  ? -28.457 13.713  10.086  1    49.46  ? 203 GLN B CB  1 
ATOM   4814 C  CG  . GLN C 1 33  ? -28.064 12.281  10.432  1    45.91  ? 203 GLN B CG  1 
ATOM   4815 C  CD  . GLN C 1 33  ? -26.862 12.188  11.344  1    45.39  ? 203 GLN B CD  1 
ATOM   4816 O  OE1 . GLN C 1 33  ? -26.271 13.195  11.747  1    47.2   ? 203 GLN B OE1 1 
ATOM   4817 N  NE2 . GLN C 1 33  ? -26.484 10.965  11.678  1    41.01  ? 203 GLN B NE2 1 
ATOM   4818 N  N   . PRO C 1 34  ? -29.488 16.613  12.14   1    55.9   ? 204 PRO B N   1 
ATOM   4819 C  CA  . PRO C 1 34  ? -29.779 18.047  12.136  1    57.71  ? 204 PRO B CA  1 
ATOM   4820 C  C   . PRO C 1 34  ? -28.816 18.854  11.275  1    56.26  ? 204 PRO B C   1 
ATOM   4821 O  O   . PRO C 1 34  ? -29.229 19.85   10.7    1    65.42  ? 204 PRO B O   1 
ATOM   4822 C  CB  . PRO C 1 34  ? -29.736 18.444  13.622  1    53.89  ? 204 PRO B CB  1 
ATOM   4823 C  CG  . PRO C 1 34  ? -28.816 17.413  14.232  1    54.91  ? 204 PRO B CG  1 
ATOM   4824 C  CD  . PRO C 1 34  ? -29.151 16.111  13.486  1    54.28  ? 204 PRO B CD  1 
ATOM   4825 N  N   . ASP C 1 35  ? -27.565 18.39   11.156  1    55.05  ? 205 ASP B N   1 
ATOM   4826 C  CA  . ASP C 1 35  ? -26.491 19.196  10.599  1    54.05  ? 205 ASP B CA  1 
ATOM   4827 C  C   . ASP C 1 35  ? -25.947 18.671  9.273   1    54.66  ? 205 ASP B C   1 
ATOM   4828 O  O   . ASP C 1 35  ? -25.155 19.369  8.645   1    57.92  ? 205 ASP B O   1 
ATOM   4829 C  CB  . ASP C 1 35  ? -25.316 19.319  11.544  1    53.36  ? 205 ASP B CB  1 
ATOM   4830 C  CG  . ASP C 1 35  ? -24.576 20.629  11.365  1    57.39  ? 205 ASP B CG  1 
ATOM   4831 O  OD1 . ASP C 1 35  ? -25.267 21.688  11.378  1    57.39  ? 205 ASP B OD1 1 
ATOM   4832 O  OD2 . ASP C 1 35  ? -23.33  20.575  11.226  1    58.42  ? 205 ASP B OD2 1 
ATOM   4833 N  N   . ILE C 1 36  ? -26.331 17.45   8.872   1    52.14  ? 206 ILE B N   1 
ATOM   4834 C  CA  . ILE C 1 36  ? -25.912 16.895  7.597   1    52.09  ? 206 ILE B CA  1 
ATOM   4835 C  C   . ILE C 1 36  ? -27.099 16.507  6.706   1    57.1   ? 206 ILE B C   1 
ATOM   4836 O  O   . ILE C 1 36  ? -28.256 16.388  7.157   1    58.29  ? 206 ILE B O   1 
ATOM   4837 C  CB  . ILE C 1 36  ? -24.866 15.78   7.763   1    53.12  ? 206 ILE B CB  1 
ATOM   4838 C  CG1 . ILE C 1 36  ? -25.428 14.535  8.402   1    53.01  ? 206 ILE B CG1 1 
ATOM   4839 C  CG2 . ILE C 1 36  ? -23.649 16.305  8.524   1    57.04  ? 206 ILE B CG2 1 
ATOM   4840 C  CD1 . ILE C 1 36  ? -24.367 13.492  8.7     1    52.59  ? 206 ILE B CD1 1 
ATOM   4841 N  N   . THR C 1 37  ? -26.752 16.345  5.408   1    54.47  ? 207 THR B N   1 
ATOM   4842 C  CA  . THR C 1 37  ? -27.637 16.332  4.247   1    51.93  ? 207 THR B CA  1 
ATOM   4843 C  C   . THR C 1 37  ? -27.082 15.345  3.23    1    52.24  ? 207 THR B C   1 
ATOM   4844 O  O   . THR C 1 37  ? -25.884 15.041  3.243   1    53.35  ? 207 THR B O   1 
ATOM   4845 C  CB  . THR C 1 37  ? -27.67  17.687  3.536   1    50.54  ? 207 THR B CB  1 
ATOM   4846 O  OG1 . THR C 1 37  ? -26.33  17.887  3.093   1    48.59  ? 207 THR B OG1 1 
ATOM   4847 C  CG2 . THR C 1 37  ? -28.17  18.831  4.387   1    47.36  ? 207 THR B CG2 1 
ATOM   4848 N  N   . ASN C 1 38  ? -27.954 14.923  2.303   1    52.1   ? 208 ASN B N   1 
ATOM   4849 C  CA  . ASN C 1 38  ? -27.571 13.951  1.295   1    52.03  ? 208 ASN B CA  1 
ATOM   4850 C  C   . ASN C 1 38  ? -26.42  14.517  0.466   1    50.56  ? 208 ASN B C   1 
ATOM   4851 O  O   . ASN C 1 38  ? -25.522 13.782  0.047   1    47.29  ? 208 ASN B O   1 
ATOM   4852 C  CB  . ASN C 1 38  ? -28.75  13.546  0.419   1    53.5   ? 208 ASN B CB  1 
ATOM   4853 C  CG  . ASN C 1 38  ? -29.84  12.873  1.219   1    54.93  ? 208 ASN B CG  1 
ATOM   4854 O  OD1 . ASN C 1 38  ? -29.566 11.978  2.028   1    52     ? 208 ASN B OD1 1 
ATOM   4855 N  ND2 . ASN C 1 38  ? -31.077 13.281  0.999   1    53.72  ? 208 ASN B ND2 1 
ATOM   4856 N  N   . SER C 1 39  ? -26.443 15.84   0.281   1    48.14  ? 209 SER B N   1 
ATOM   4857 C  CA  . SER C 1 39  ? -25.444 16.488  -0.544  1    51.28  ? 209 SER B CA  1 
ATOM   4858 C  C   . SER C 1 39  ? -24.049 16.353  0.078   1    50.11  ? 209 SER B C   1 
ATOM   4859 O  O   . SER C 1 39  ? -23.066 16.124  -0.635  1    48.23  ? 209 SER B O   1 
ATOM   4860 C  CB  . SER C 1 39  ? -25.864 17.907  -0.836  1    57.2   ? 209 SER B CB  1 
ATOM   4861 O  OG  . SER C 1 39  ? -24.742 18.765  -1.003  1    65.21  ? 209 SER B OG  1 
ATOM   4862 N  N   . MET C 1 40  ? -23.97  16.479  1.411   1    49.64  ? 210 MET B N   1 
ATOM   4863 C  CA  . MET C 1 40  ? -22.701 16.388  2.119   1    47.74  ? 210 MET B CA  1 
ATOM   4864 C  C   . MET C 1 40  ? -22.151 14.963  2.105   1    46.76  ? 210 MET B C   1 
ATOM   4865 O  O   . MET C 1 40  ? -20.94  14.763  2.075   1    48.44  ? 210 MET B O   1 
ATOM   4866 C  CB  . MET C 1 40  ? -22.846 16.833  3.572   1    44.12  ? 210 MET B CB  1 
ATOM   4867 C  CG  . MET C 1 40  ? -22.907 18.323  3.727   1    47.21  ? 210 MET B CG  1 
ATOM   4868 S  SD  . MET C 1 40  ? -23.276 18.68   5.457   1    53.84  ? 210 MET B SD  1 
ATOM   4869 C  CE  . MET C 1 40  ? -23.958 20.337  5.272   1    50.54  ? 210 MET B CE  1 
ATOM   4870 N  N   . ARG C 1 41  ? -23.049 13.98   2.178   1    47.18  ? 211 ARG B N   1 
ATOM   4871 C  CA  . ARG C 1 41  ? -22.673 12.573  2.199   1    44.36  ? 211 ARG B CA  1 
ATOM   4872 C  C   . ARG C 1 41  ? -22.136 12.199  0.823   1    44.13  ? 211 ARG B C   1 
ATOM   4873 O  O   . ARG C 1 41  ? -21.226 11.382  0.707   1    44.93  ? 211 ARG B O   1 
ATOM   4874 C  CB  . ARG C 1 41  ? -23.921 11.765  2.575   1    44.21  ? 211 ARG B CB  1 
ATOM   4875 C  CG  . ARG C 1 41  ? -23.767 10.26   2.49    1    44.95  ? 211 ARG B CG  1 
ATOM   4876 C  CD  . ARG C 1 41  ? -25.147 9.612   2.575   1    47.88  ? 211 ARG B CD  1 
ATOM   4877 N  NE  . ARG C 1 41  ? -25.027 8.185   2.249   1    46.11  ? 211 ARG B NE  1 
ATOM   4878 C  CZ  . ARG C 1 41  ? -24.72  7.686   1.051   1    42.95  ? 211 ARG B CZ  1 
ATOM   4879 N  NH1 . ARG C 1 41  ? -24.754 8.45    -0.026  1    40.29  ? 211 ARG B NH1 1 
ATOM   4880 N  NH2 . ARG C 1 41  ? -24.377 6.407   0.941   1    40.87  ? 211 ARG B NH2 1 
ATOM   4881 N  N   . ALA C 1 42  ? -22.709 12.833  -0.209  1    44.11  ? 212 ALA B N   1 
ATOM   4882 C  CA  . ALA C 1 42  ? -22.374 12.573  -1.601  1    41.44  ? 212 ALA B CA  1 
ATOM   4883 C  C   . ALA C 1 42  ? -20.954 13.067  -1.869  1    44.43  ? 212 ALA B C   1 
ATOM   4884 O  O   . ALA C 1 42  ? -20.164 12.389  -2.523  1    45.73  ? 212 ALA B O   1 
ATOM   4885 C  CB  . ALA C 1 42  ? -23.397 13.245  -2.493  1    37.13  ? 212 ALA B CB  1 
ATOM   4886 N  N   . ILE C 1 43  ? -20.636 14.249  -1.325  1    44.65  ? 213 ILE B N   1 
ATOM   4887 C  CA  . ILE C 1 43  ? -19.292 14.786  -1.36   1    43.56  ? 213 ILE B CA  1 
ATOM   4888 C  C   . ILE C 1 43  ? -18.33  13.807  -0.686  1    43.05  ? 213 ILE B C   1 
ATOM   4889 O  O   . ILE C 1 43  ? -17.229 13.572  -1.195  1    44.55  ? 213 ILE B O   1 
ATOM   4890 C  CB  . ILE C 1 43  ? -19.269 16.172  -0.701  1    45.07  ? 213 ILE B CB  1 
ATOM   4891 C  CG1 . ILE C 1 43  ? -20.034 17.213  -1.551  1    44.17  ? 213 ILE B CG1 1 
ATOM   4892 C  CG2 . ILE C 1 43  ? -17.829 16.608  -0.395  1    43.31  ? 213 ILE B CG2 1 
ATOM   4893 C  CD1 . ILE C 1 43  ? -20.204 18.565  -0.872  1    41.17  ? 213 ILE B CD1 1 
ATOM   4894 N  N   . LEU C 1 44  ? -18.755 13.24   0.449   1    39.04  ? 214 LEU B N   1 
ATOM   4895 C  CA  . LEU C 1 44  ? -17.913 12.33   1.216   1    41.63  ? 214 LEU B CA  1 
ATOM   4896 C  C   . LEU C 1 44  ? -17.662 11.028  0.44    1    43.9   ? 214 LEU B C   1 
ATOM   4897 O  O   . LEU C 1 44  ? -16.513 10.622  0.217   1    40.91  ? 214 LEU B O   1 
ATOM   4898 C  CB  . LEU C 1 44  ? -18.535 12.108  2.593   1    38.88  ? 214 LEU B CB  1 
ATOM   4899 C  CG  . LEU C 1 44  ? -17.917 10.977  3.423   1    39.38  ? 214 LEU B CG  1 
ATOM   4900 C  CD1 . LEU C 1 44  ? -16.544 11.346  3.948   1    39.75  ? 214 LEU B CD1 1 
ATOM   4901 C  CD2 . LEU C 1 44  ? -18.819 10.569  4.582   1    35.35  ? 214 LEU B CD2 1 
ATOM   4902 N  N   . VAL C 1 45  ? -18.745 10.408  -0.042  1    44.3   ? 215 VAL B N   1 
ATOM   4903 C  CA  . VAL C 1 45  ? -18.588 9.183   -0.808  1    45.24  ? 215 VAL B CA  1 
ATOM   4904 C  C   . VAL C 1 45  ? -17.697 9.448   -2.026  1    46.65  ? 215 VAL B C   1 
ATOM   4905 O  O   . VAL C 1 45  ? -16.854 8.627   -2.4    1    46.96  ? 215 VAL B O   1 
ATOM   4906 C  CB  . VAL C 1 45  ? -19.943 8.564   -1.185  1    39.84  ? 215 VAL B CB  1 
ATOM   4907 C  CG1 . VAL C 1 45  ? -19.756 7.256   -1.933  1    34.45  ? 215 VAL B CG1 1 
ATOM   4908 C  CG2 . VAL C 1 45  ? -20.764 8.321   0.07    1    37.68  ? 215 VAL B CG2 1 
ATOM   4909 N  N   . ASP C 1 46  ? -17.889 10.607  -2.648  1    42.96  ? 216 ASP B N   1 
ATOM   4910 C  CA  . ASP C 1 46  ? -17.149 10.917  -3.854  1    43.6   ? 216 ASP B CA  1 
ATOM   4911 C  C   . ASP C 1 46  ? -15.657 10.952  -3.534  1    44.89  ? 216 ASP B C   1 
ATOM   4912 O  O   . ASP C 1 46  ? -14.825 10.532  -4.343  1    46.71  ? 216 ASP B O   1 
ATOM   4913 C  CB  . ASP C 1 46  ? -17.588 12.25   -4.43   1    43.9   ? 216 ASP B CB  1 
ATOM   4914 C  CG  . ASP C 1 46  ? -16.984 12.56   -5.788  1    45.29  ? 216 ASP B CG  1 
ATOM   4915 O  OD1 . ASP C 1 46  ? -17.449 11.979  -6.795  1    44.7   ? 216 ASP B OD1 1 
ATOM   4916 O  OD2 . ASP C 1 46  ? -16.005 13.319  -5.814  1    46.6   ? 216 ASP B OD2 1 
ATOM   4917 N  N   . TRP C 1 47  ? -15.337 11.487  -2.35   1    44.09  ? 217 TRP B N   1 
ATOM   4918 C  CA  . TRP C 1 47  ? -13.967 11.659  -1.908  1    42.1   ? 217 TRP B CA  1 
ATOM   4919 C  C   . TRP C 1 47  ? -13.339 10.286  -1.635  1    45.57  ? 217 TRP B C   1 
ATOM   4920 O  O   . TRP C 1 47  ? -12.172 10.023  -1.961  1    47.82  ? 217 TRP B O   1 
ATOM   4921 C  CB  . TRP C 1 47  ? -13.966 12.578  -0.679  1    40.05  ? 217 TRP B CB  1 
ATOM   4922 C  CG  . TRP C 1 47  ? -12.639 12.658  0.018   1    42.39  ? 217 TRP B CG  1 
ATOM   4923 C  CD1 . TRP C 1 47  ? -11.528 13.31   -0.43   1    44.73  ? 217 TRP B CD1 1 
ATOM   4924 C  CD2 . TRP C 1 47  ? -12.271 12.077  1.281   1    41.89  ? 217 TRP B CD2 1 
ATOM   4925 N  NE1 . TRP C 1 47  ? -10.491 13.168  0.451   1    42.33  ? 217 TRP B NE1 1 
ATOM   4926 C  CE2 . TRP C 1 47  ? -10.918 12.425  1.512   1    44.09  ? 217 TRP B CE2 1 
ATOM   4927 C  CE3 . TRP C 1 47  ? -12.935 11.3    2.226   1    42.58  ? 217 TRP B CE3 1 
ATOM   4928 C  CZ2 . TRP C 1 47  ? -10.23  12.037  2.656   1    45.27  ? 217 TRP B CZ2 1 
ATOM   4929 C  CZ3 . TRP C 1 47  ? -12.248 10.895  3.351   1    44.69  ? 217 TRP B CZ3 1 
ATOM   4930 C  CH2 . TRP C 1 47  ? -10.926 11.271  3.567   1    47.53  ? 217 TRP B CH2 1 
ATOM   4931 N  N   . LEU C 1 48  ? -14.131 9.382   -1.046  1    43.13  ? 218 LEU B N   1 
ATOM   4932 C  CA  . LEU C 1 48  ? -13.634 8.061   -0.711  1    41.56  ? 218 LEU B CA  1 
ATOM   4933 C  C   . LEU C 1 48  ? -13.408 7.269   -1.987  1    44.1   ? 218 LEU B C   1 
ATOM   4934 O  O   . LEU C 1 48  ? -12.644 6.307   -1.963  1    48.91  ? 218 LEU B O   1 
ATOM   4935 C  CB  . LEU C 1 48  ? -14.685 7.373   0.149   1    42.43  ? 218 LEU B CB  1 
ATOM   4936 C  CG  . LEU C 1 48  ? -14.867 7.964   1.54    1    41.49  ? 218 LEU B CG  1 
ATOM   4937 C  CD1 . LEU C 1 48  ? -16.083 7.31    2.137   1    39.39  ? 218 LEU B CD1 1 
ATOM   4938 C  CD2 . LEU C 1 48  ? -13.595 7.721   2.341   1    39.59  ? 218 LEU B CD2 1 
ATOM   4939 N  N   . VAL C 1 49  ? -14.102 7.66    -3.067  1    39.51  ? 219 VAL B N   1 
ATOM   4940 C  CA  . VAL C 1 49  ? -13.854 7.086   -4.376  1    40.03  ? 219 VAL B CA  1 
ATOM   4941 C  C   . VAL C 1 49  ? -12.461 7.496   -4.853  1    45.17  ? 219 VAL B C   1 
ATOM   4942 O  O   . VAL C 1 49  ? -11.711 6.646   -5.336  1    45.8   ? 219 VAL B O   1 
ATOM   4943 C  CB  . VAL C 1 49  ? -14.948 7.476   -5.378  1    37.91  ? 219 VAL B CB  1 
ATOM   4944 C  CG1 . VAL C 1 49  ? -14.56  7.141   -6.807  1    36.55  ? 219 VAL B CG1 1 
ATOM   4945 C  CG2 . VAL C 1 49  ? -16.261 6.813   -5.022  1    37.6   ? 219 VAL B CG2 1 
ATOM   4946 N  N   . GLU C 1 50  ? -12.118 8.786   -4.704  1    45.78  ? 220 GLU B N   1 
ATOM   4947 C  CA  . GLU C 1 50  ? -10.784 9.251   -5.046  1    49.7   ? 220 GLU B CA  1 
ATOM   4948 C  C   . GLU C 1 50  ? -9.725  8.543   -4.196  1    49.48  ? 220 GLU B C   1 
ATOM   4949 O  O   . GLU C 1 50  ? -8.685  8.155   -4.717  1    50.46  ? 220 GLU B O   1 
ATOM   4950 C  CB  . GLU C 1 50  ? -10.597 10.739  -4.772  1    54.74  ? 220 GLU B CB  1 
ATOM   4951 C  CG  . GLU C 1 50  ? -11.409 11.636  -5.693  1    66.77  ? 220 GLU B CG  1 
ATOM   4952 C  CD  . GLU C 1 50  ? -10.936 13.071  -5.612  1    72.27  ? 220 GLU B CD  1 
ATOM   4953 O  OE1 . GLU C 1 50  ? -10.763 13.694  -6.696  1    74.95  ? 220 GLU B OE1 1 
ATOM   4954 O  OE2 . GLU C 1 50  ? -10.717 13.523  -4.458  1    66.96  ? 220 GLU B OE2 1 
ATOM   4955 N  N   . VAL C 1 51  ? -9.954  8.427   -2.892  1    46.08  ? 221 VAL B N   1 
ATOM   4956 C  CA  . VAL C 1 51  ? -8.928  7.83    -1.991  1    47.03  ? 221 VAL B CA  1 
ATOM   4957 C  C   . VAL C 1 51  ? -8.677  6.383   -2.422  1    45.8   ? 221 VAL B C   1 
ATOM   4958 O  O   . VAL C 1 51  ? -7.511  5.955   -2.421  1    48.57  ? 221 VAL B O   1 
ATOM   4959 C  CB  . VAL C 1 51  ? -9.393  7.917   -0.53   1    45.38  ? 221 VAL B CB  1 
ATOM   4960 C  CG1 . VAL C 1 51  ? -8.505  7.121   0.416   1    39.88  ? 221 VAL B CG1 1 
ATOM   4961 C  CG2 . VAL C 1 51  ? -9.569  9.357   -0.079  1    45.08  ? 221 VAL B CG2 1 
ATOM   4962 N  N   . GLY C 1 52  ? -9.737  5.679   -2.799  1    41.5   ? 222 GLY B N   1 
ATOM   4963 C  CA  . GLY C 1 52  ? -9.597  4.281   -3.221  1    42.57  ? 222 GLY B CA  1 
ATOM   4964 C  C   . GLY C 1 52  ? -8.735  4.174   -4.446  1    48.35  ? 222 GLY B C   1 
ATOM   4965 O  O   . GLY C 1 52  ? -8.007  3.183   -4.565  1    53.64  ? 222 GLY B O   1 
ATOM   4966 N  N   . GLU C 1 53  ? -8.821  5.155   -5.344  1    48.83  ? 223 GLU B N   1 
ATOM   4967 C  CA  . GLU C 1 53  ? -8.035  5.097   -6.602  1    54.75  ? 223 GLU B CA  1 
ATOM   4968 C  C   . GLU C 1 53  ? -6.598  5.544   -6.299  1    56.69  ? 223 GLU B C   1 
ATOM   4969 O  O   . GLU C 1 53  ? -5.662  5.01    -6.932  1    60.79  ? 223 GLU B O   1 
ATOM   4970 C  CB  . GLU C 1 53  ? -8.713  5.94    -7.681  1    59.51  ? 223 GLU B CB  1 
ATOM   4971 C  CG  . GLU C 1 53  ? -9.89   5.22    -8.329  1    66.34  ? 223 GLU B CG  1 
ATOM   4972 C  CD  . GLU C 1 53  ? -9.702  3.721   -8.49   1    84.07  ? 223 GLU B CD  1 
ATOM   4973 O  OE1 . GLU C 1 53  ? -9.115  3.311   -9.514  1    94.83  ? 223 GLU B OE1 1 
ATOM   4974 O  OE2 . GLU C 1 53  ? -10.149 2.958   -7.605  1    79.45  ? 223 GLU B OE2 1 
ATOM   4975 N  N   . GLU C 1 54  ? -6.44   6.471   -5.353  1    58.87  ? 224 GLU B N   1 
ATOM   4976 C  CA  . GLU C 1 54  ? -5.095  6.972   -5.003  1    59.21  ? 224 GLU B CA  1 
ATOM   4977 C  C   . GLU C 1 54  ? -4.287  5.838   -4.37   1    59.67  ? 224 GLU B C   1 
ATOM   4978 O  O   . GLU C 1 54  ? -3.111  5.686   -4.733  1    57.85  ? 224 GLU B O   1 
ATOM   4979 C  CB  . GLU C 1 54  ? -5.277  8.158   -4.062  1    61.12  ? 224 GLU B CB  1 
ATOM   4980 C  CG  . GLU C 1 54  ? -4.084  8.414   -3.149  1    76.03  ? 224 GLU B CG  1 
ATOM   4981 C  CD  . GLU C 1 54  ? -3.002  9.256   -3.796  1    81.84  ? 224 GLU B CD  1 
ATOM   4982 O  OE1 . GLU C 1 54  ? -3.298  9.923   -4.808  1    81.74  ? 224 GLU B OE1 1 
ATOM   4983 O  OE2 . GLU C 1 54  ? -1.864  9.24    -3.287  1    87.56  ? 224 GLU B OE2 1 
ATOM   4984 N  N   . TYR C 1 55  ? -4.899  5.07    -3.473  1    56.59  ? 225 TYR B N   1 
ATOM   4985 C  CA  . TYR C 1 55  ? -4.161  4.008   -2.743  1    54.01  ? 225 TYR B CA  1 
ATOM   4986 C  C   . TYR C 1 55  ? -4.41   2.694   -3.432  1    51.66  ? 225 TYR B C   1 
ATOM   4987 O  O   . TYR C 1 55  ? -4.041  1.646   -2.884  1    49.84  ? 225 TYR B O   1 
ATOM   4988 C  CB  . TYR C 1 55  ? -4.615  4.092   -1.287  1    53.15  ? 225 TYR B CB  1 
ATOM   4989 C  CG  . TYR C 1 55  ? -4.029  5.29    -0.558  1    57.26  ? 225 TYR B CG  1 
ATOM   4990 C  CD1 . TYR C 1 55  ? -2.681  5.338   -0.235  1    58.98  ? 225 TYR B CD1 1 
ATOM   4991 C  CD2 . TYR C 1 55  ? -4.819  6.375   -0.211  1    59.06  ? 225 TYR B CD2 1 
ATOM   4992 C  CE1 . TYR C 1 55  ? -2.136  6.427   0.421   1    61.8   ? 225 TYR B CE1 1 
ATOM   4993 C  CE2 . TYR C 1 55  ? -4.287  7.47    0.445   1    61.19  ? 225 TYR B CE2 1 
ATOM   4994 C  CZ  . TYR C 1 55  ? -2.942  7.497   0.761   1    62.81  ? 225 TYR B CZ  1 
ATOM   4995 O  OH  . TYR C 1 55  ? -2.41   8.572   1.407   1    69.64  ? 225 TYR B OH  1 
ATOM   4996 N  N   . LYS C 1 56  ? -5.016  2.758   -4.611  1    52.82  ? 226 LYS B N   1 
ATOM   4997 C  CA  . LYS C 1 56  ? -5.274  1.544   -5.424  1    55.86  ? 226 LYS B CA  1 
ATOM   4998 C  C   . LYS C 1 56  ? -5.97   0.489   -4.559  1    53.47  ? 226 LYS B C   1 
ATOM   4999 O  O   . LYS C 1 56  ? -5.505  -0.661  -4.537  1    55.32  ? 226 LYS B O   1 
ATOM   5000 C  CB  . LYS C 1 56  ? -3.961  1.164   -6.114  1    58.82  ? 226 LYS B CB  1 
ATOM   5001 C  CG  . LYS C 1 56  ? -3.525  2.188   -7.15   1    73.85  ? 226 LYS B CG  1 
ATOM   5002 C  CD  . LYS C 1 56  ? -2.205  1.827   -7.823  1    89.13  ? 226 LYS B CD  1 
ATOM   5003 C  CE  . LYS C 1 56  ? -1.749  2.798   -8.87   1    99.83  ? 226 LYS B CE  1 
ATOM   5004 N  NZ  . LYS C 1 56  ? -0.466  2.398   -9.454  1    97.32  ? 226 LYS B NZ  1 
ATOM   5005 N  N   . LEU C 1 57  ? -7.066  0.876   -3.909  1    49.2   ? 227 LEU B N   1 
ATOM   5006 C  CA  . LEU C 1 57  ? -7.843  -0.034  -3.082  1    44.61  ? 227 LEU B CA  1 
ATOM   5007 C  C   . LEU C 1 57  ? -8.83   -0.777  -3.968  1    44.3   ? 227 LEU B C   1 
ATOM   5008 O  O   . LEU C 1 57  ? -9.091  -0.356  -5.09   1    46.53  ? 227 LEU B O   1 
ATOM   5009 C  CB  . LEU C 1 57  ? -8.574  0.731   -1.985  1    41.25  ? 227 LEU B CB  1 
ATOM   5010 C  CG  . LEU C 1 57  ? -7.67   1.485   -1.003  1    39.98  ? 227 LEU B CG  1 
ATOM   5011 C  CD1 . LEU C 1 57  ? -8.487  2.264   -0.022  1    36.85  ? 227 LEU B CD1 1 
ATOM   5012 C  CD2 . LEU C 1 57  ? -6.721  0.562   -0.269  1    39.13  ? 227 LEU B CD2 1 
ATOM   5013 N  N   . GLN C 1 58  ? -9.358  -1.892  -3.451  1    44.28  ? 228 GLN B N   1 
ATOM   5014 C  CA  . GLN C 1 58  ? -10.415 -2.634  -4.121  1    42.5   ? 228 GLN B CA  1 
ATOM   5015 C  C   . GLN C 1 58  ? -11.744 -1.883  -4.053  1    41.39  ? 228 GLN B C   1 
ATOM   5016 O  O   . GLN C 1 58  ? -11.983 -1.057  -3.167  1    42.78  ? 228 GLN B O   1 
ATOM   5017 C  CB  . GLN C 1 58  ? -10.664 -3.955  -3.402  1    43.15  ? 228 GLN B CB  1 
ATOM   5018 C  CG  . GLN C 1 58  ? -9.437  -4.844  -3.302  1    44.94  ? 228 GLN B CG  1 
ATOM   5019 C  CD  . GLN C 1 58  ? -9.039  -5.409  -4.648  1    45.92  ? 228 GLN B CD  1 
ATOM   5020 O  OE1 . GLN C 1 58  ? -9.827  -6.065  -5.33   1    48.39  ? 228 GLN B OE1 1 
ATOM   5021 N  NE2 . GLN C 1 58  ? -7.794  -5.188  -5.021  1    43.56  ? 228 GLN B NE2 1 
ATOM   5022 N  N   . ASN C 1 59  ? -12.63  -2.241  -4.972  1    42.15  ? 229 ASN B N   1 
ATOM   5023 C  CA  . ASN C 1 59  ? -13.931 -1.609  -5.051  1    42.39  ? 229 ASN B CA  1 
ATOM   5024 C  C   . ASN C 1 59  ? -14.795 -2.134  -3.918  1    44.6   ? 229 ASN B C   1 
ATOM   5025 O  O   . ASN C 1 59  ? -15.756 -1.463  -3.527  1    50.37  ? 229 ASN B O   1 
ATOM   5026 C  CB  . ASN C 1 59  ? -14.615 -1.879  -6.381  1    40.9   ? 229 ASN B CB  1 
ATOM   5027 C  CG  . ASN C 1 59  ? -13.977 -1.151  -7.531  1    43.55  ? 229 ASN B CG  1 
ATOM   5028 O  OD1 . ASN C 1 59  ? -13.023 -0.401  -7.346  1    50.36  ? 229 ASN B OD1 1 
ATOM   5029 N  ND2 . ASN C 1 59  ? -14.491 -1.356  -8.728  1    50.18  ? 229 ASN B ND2 1 
ATOM   5030 N  N   . GLU C 1 60  ? -14.467 -3.35   -3.448  1    42.62  ? 230 GLU B N   1 
ATOM   5031 C  CA  . GLU C 1 60  ? -15.186 -3.983  -2.351  1    38.75  ? 230 GLU B CA  1 
ATOM   5032 C  C   . GLU C 1 60  ? -14.993 -3.108  -1.117  1    42.1   ? 230 GLU B C   1 
ATOM   5033 O  O   . GLU C 1 60  ? -15.937 -2.856  -0.348  1    46.18  ? 230 GLU B O   1 
ATOM   5034 C  CB  . GLU C 1 60  ? -14.663 -5.401  -2.109  1    35     ? 230 GLU B CB  1 
ATOM   5035 C  CG  . GLU C 1 60  ? -15.352 -6.152  -0.969  1    38.42  ? 230 GLU B CG  1 
ATOM   5036 C  CD  . GLU C 1 60  ? -16.845 -6.371  -1.162  1    40.28  ? 230 GLU B CD  1 
ATOM   5037 O  OE1 . GLU C 1 60  ? -17.362 -6.209  -2.281  1    48.48  ? 230 GLU B OE1 1 
ATOM   5038 O  OE2 . GLU C 1 60  ? -17.495 -6.727  -0.194  1    35.77  ? 230 GLU B OE2 1 
ATOM   5039 N  N   . THR C 1 61  ? -13.75  -2.634  -0.964  1    38.02  ? 231 THR B N   1 
ATOM   5040 C  CA  . THR C 1 61  ? -13.368 -1.845  0.191   1    40.58  ? 231 THR B CA  1 
ATOM   5041 C  C   . THR C 1 61  ? -14.261 -0.596  0.24    1    41.97  ? 231 THR B C   1 
ATOM   5042 O  O   . THR C 1 61  ? -14.817 -0.258  1.293   1    40.92  ? 231 THR B O   1 
ATOM   5043 C  CB  . THR C 1 61  ? -11.868 -1.534  0.141   1    38.76  ? 231 THR B CB  1 
ATOM   5044 O  OG1 . THR C 1 61  ? -11.106 -2.718  -0.092  1    35.5   ? 231 THR B OG1 1 
ATOM   5045 C  CG2 . THR C 1 61  ? -11.38  -0.878  1.418   1    39.01  ? 231 THR B CG2 1 
ATOM   5046 N  N   . LEU C 1 62  ? -14.421 0.057   -0.918  1    37.58  ? 232 LEU B N   1 
ATOM   5047 C  CA  . LEU C 1 62  ? -15.203 1.273   -1.001  1    38.62  ? 232 LEU B CA  1 
ATOM   5048 C  C   . LEU C 1 62  ? -16.642 0.978   -0.592  1    38.09  ? 232 LEU B C   1 
ATOM   5049 O  O   . LEU C 1 62  ? -17.203 1.715   0.228   1    39.92  ? 232 LEU B O   1 
ATOM   5050 C  CB  . LEU C 1 62  ? -15.121 1.852   -2.411  1    42.21  ? 232 LEU B CB  1 
ATOM   5051 C  CG  . LEU C 1 62  ? -16.149 2.936   -2.755  1    40.41  ? 232 LEU B CG  1 
ATOM   5052 C  CD1 . LEU C 1 62  ? -15.885 4.261   -2.025  1    37.63  ? 232 LEU B CD1 1 
ATOM   5053 C  CD2 . LEU C 1 62  ? -16.211 3.132   -4.268  1    39.3   ? 232 LEU B CD2 1 
ATOM   5054 N  N   . HIS C 1 63  ? -17.209 -0.111  -1.141  1    36.14  ? 233 HIS B N   1 
ATOM   5055 C  CA  . HIS C 1 63  ? -18.581 -0.507  -0.813  1    36     ? 233 HIS B CA  1 
ATOM   5056 C  C   . HIS C 1 63  ? -18.753 -0.805  0.684   1    36.66  ? 233 HIS B C   1 
ATOM   5057 O  O   . HIS C 1 63  ? -19.756 -0.442  1.284   1    36.72  ? 233 HIS B O   1 
ATOM   5058 C  CB  . HIS C 1 63  ? -19.026 -1.712  -1.639  1    35.83  ? 233 HIS B CB  1 
ATOM   5059 C  CG  . HIS C 1 63  ? -19.571 -1.383  -2.981  1    40.03  ? 233 HIS B CG  1 
ATOM   5060 N  ND1 . HIS C 1 63  ? -18.75  -1.134  -4.065  1    41.6   ? 233 HIS B ND1 1 
ATOM   5061 C  CD2 . HIS C 1 63  ? -20.839 -1.266  -3.418  1    37.84  ? 233 HIS B CD2 1 
ATOM   5062 C  CE1 . HIS C 1 63  ? -19.513 -0.851  -5.12   1    40.61  ? 233 HIS B CE1 1 
ATOM   5063 N  NE2 . HIS C 1 63  ? -20.778 -0.97   -4.755  1    42.15  ? 233 HIS B NE2 1 
ATOM   5064 N  N   . LEU C 1 64  ? -17.777 -1.485  1.291   1    37.56  ? 234 LEU B N   1 
ATOM   5065 C  CA  . LEU C 1 64  ? -17.836 -1.754  2.712   1    37.43  ? 234 LEU B CA  1 
ATOM   5066 C  C   . LEU C 1 64  ? -17.811 -0.427  3.475   1    41.25  ? 234 LEU B C   1 
ATOM   5067 O  O   . LEU C 1 64  ? -18.613 -0.244  4.392   1    39.82  ? 234 LEU B O   1 
ATOM   5068 C  CB  . LEU C 1 64  ? -16.662 -2.643  3.113   1    33.75  ? 234 LEU B CB  1 
ATOM   5069 C  CG  . LEU C 1 64  ? -16.729 -4.107  2.7     1    32.89  ? 234 LEU B CG  1 
ATOM   5070 C  CD1 . LEU C 1 64  ? -15.345 -4.706  2.964   1    31.43  ? 234 LEU B CD1 1 
ATOM   5071 C  CD2 . LEU C 1 64  ? -17.86  -4.866  3.438   1    32.15  ? 234 LEU B CD2 1 
ATOM   5072 N  N   . ALA C 1 65  ? -16.9   0.493   3.103   1    39.33  ? 235 ALA B N   1 
ATOM   5073 C  CA  . ALA C 1 65  ? -16.76  1.735   3.858   1    41.7   ? 235 ALA B CA  1 
ATOM   5074 C  C   . ALA C 1 65  ? -18.103 2.474   3.94    1    40.85  ? 235 ALA B C   1 
ATOM   5075 O  O   . ALA C 1 65  ? -18.513 2.978   4.992   1    39.87  ? 235 ALA B O   1 
ATOM   5076 C  CB  . ALA C 1 65  ? -15.682 2.61    3.25    1    38.24  ? 235 ALA B CB  1 
ATOM   5077 N  N   . VAL C 1 66  ? -18.784 2.536   2.797   1    35.84  ? 236 VAL B N   1 
ATOM   5078 C  CA  . VAL C 1 66  ? -20.046 3.235   2.715   1    35.08  ? 236 VAL B CA  1 
ATOM   5079 C  C   . VAL C 1 66  ? -21.118 2.516   3.549   1    37.73  ? 236 VAL B C   1 
ATOM   5080 O  O   . VAL C 1 66  ? -21.962 3.165   4.169   1    42.77  ? 236 VAL B O   1 
ATOM   5081 C  CB  . VAL C 1 66  ? -20.393 3.374   1.224   1    32.81  ? 236 VAL B CB  1 
ATOM   5082 C  CG1 . VAL C 1 66  ? -21.805 3.928   1.033   1    32.49  ? 236 VAL B CG1 1 
ATOM   5083 C  CG2 . VAL C 1 66  ? -19.342 4.23    0.517   1    31.91  ? 236 VAL B CG2 1 
ATOM   5084 N  N   . ASN C 1 67  ? -21.076 1.183   3.624   1    34.39  ? 237 ASN B N   1 
ATOM   5085 C  CA  . ASN C 1 67  ? -22.023 0.451   4.455   1    34.42  ? 237 ASN B CA  1 
ATOM   5086 C  C   . ASN C 1 67  ? -21.82  0.838   5.914   1    34.78  ? 237 ASN B C   1 
ATOM   5087 O  O   . ASN C 1 67  ? -22.795 1.069   6.631   1    37.56  ? 237 ASN B O   1 
ATOM   5088 C  CB  . ASN C 1 67  ? -21.877 -1.057  4.274   1    35.72  ? 237 ASN B CB  1 
ATOM   5089 C  CG  . ASN C 1 67  ? -22.717 -1.824  5.254   1    38.81  ? 237 ASN B CG  1 
ATOM   5090 O  OD1 . ASN C 1 67  ? -22.232 -2.277  6.302   1    48.5   ? 237 ASN B OD1 1 
ATOM   5091 N  ND2 . ASN C 1 67  ? -24.001 -1.903  4.971   1    42.47  ? 237 ASN B ND2 1 
ATOM   5092 N  N   . TYR C 1 68  ? -20.546 0.881   6.338   1    35.02  ? 238 TYR B N   1 
ATOM   5093 C  CA  . TYR C 1 68  ? -20.136 1.273   7.683   1    35.78  ? 238 TYR B CA  1 
ATOM   5094 C  C   . TYR C 1 68  ? -20.639 2.682   7.999   1    40.38  ? 238 TYR B C   1 
ATOM   5095 O  O   . TYR C 1 68  ? -21.161 2.913   9.088   1    45.63  ? 238 TYR B O   1 
ATOM   5096 C  CB  . TYR C 1 68  ? -18.622 1.174   7.895   1    36.14  ? 238 TYR B CB  1 
ATOM   5097 C  CG  . TYR C 1 68  ? -18.023 -0.21   7.669   1    36.46  ? 238 TYR B CG  1 
ATOM   5098 C  CD1 . TYR C 1 68  ? -18.819 -1.349  7.531   1    34.05  ? 238 TYR B CD1 1 
ATOM   5099 C  CD2 . TYR C 1 68  ? -16.648 -0.371  7.584   1    35.25  ? 238 TYR B CD2 1 
ATOM   5100 C  CE1 . TYR C 1 68  ? -18.264 -2.601  7.311   1    35.15  ? 238 TYR B CE1 1 
ATOM   5101 C  CE2 . TYR C 1 68  ? -16.08  -1.616  7.361   1    36.13  ? 238 TYR B CE2 1 
ATOM   5102 C  CZ  . TYR C 1 68  ? -16.887 -2.74   7.238   1    36.88  ? 238 TYR B CZ  1 
ATOM   5103 O  OH  . TYR C 1 68  ? -16.302 -3.964  7.006   1    38.04  ? 238 TYR B OH  1 
ATOM   5104 N  N   . ILE C 1 69  ? -20.506 3.607   7.041   1    37.09  ? 239 ILE B N   1 
ATOM   5105 C  CA  . ILE C 1 69  ? -20.872 4.992   7.28    1    38.43  ? 239 ILE B CA  1 
ATOM   5106 C  C   . ILE C 1 69  ? -22.384 5.099   7.514   1    40.68  ? 239 ILE B C   1 
ATOM   5107 O  O   . ILE C 1 69  ? -22.836 5.687   8.515   1    40.62  ? 239 ILE B O   1 
ATOM   5108 C  CB  . ILE C 1 69  ? -20.364 5.888   6.133   1    37.08  ? 239 ILE B CB  1 
ATOM   5109 C  CG1 . ILE C 1 69  ? -18.852 5.905   6.071   1    35.01  ? 239 ILE B CG1 1 
ATOM   5110 C  CG2 . ILE C 1 69  ? -20.901 7.312   6.264   1    35.68  ? 239 ILE B CG2 1 
ATOM   5111 C  CD1 . ILE C 1 69  ? -18.308 6.566   4.827   1    35.48  ? 239 ILE B CD1 1 
ATOM   5112 N  N   . ASP C 1 70  ? -23.158 4.493   6.601   1    39.16  ? 240 ASP B N   1 
ATOM   5113 C  CA  . ASP C 1 70  ? -24.609 4.62    6.629   1    41.92  ? 240 ASP B CA  1 
ATOM   5114 C  C   . ASP C 1 70  ? -25.188 3.958   7.88    1    43.94  ? 240 ASP B C   1 
ATOM   5115 O  O   . ASP C 1 70  ? -26.152 4.463   8.444   1    45.41  ? 240 ASP B O   1 
ATOM   5116 C  CB  . ASP C 1 70  ? -25.28  4.096   5.369   1    40.93  ? 240 ASP B CB  1 
ATOM   5117 C  CG  . ASP C 1 70  ? -25.009 4.886   4.097   1    41.07  ? 240 ASP B CG  1 
ATOM   5118 O  OD1 . ASP C 1 70  ? -24.933 6.11    4.185   1    39.89  ? 240 ASP B OD1 1 
ATOM   5119 O  OD2 . ASP C 1 70  ? -24.931 4.27    3.016   1    40.85  ? 240 ASP B OD2 1 
ATOM   5120 N  N   . ARG C 1 71  ? -24.576 2.849   8.299   1    40.83  ? 241 ARG B N   1 
ATOM   5121 C  CA  . ARG C 1 71  ? -25.026 2.176   9.543   1    40.05  ? 241 ARG B CA  1 
ATOM   5122 C  C   . ARG C 1 71  ? -24.637 3.056   10.741  1    38.99  ? 241 ARG B C   1 
ATOM   5123 O  O   . ARG C 1 71  ? -25.429 3.127   11.706  1    40.22  ? 241 ARG B O   1 
ATOM   5124 C  CB  . ARG C 1 71  ? -24.412 0.776   9.638   1    36.05  ? 241 ARG B CB  1 
ATOM   5125 C  CG  . ARG C 1 71  ? -25.066 -0.222  8.694   1    36.58  ? 241 ARG B CG  1 
ATOM   5126 C  CD  . ARG C 1 71  ? -24.434 -1.597  8.813   1    38.74  ? 241 ARG B CD  1 
ATOM   5127 N  NE  . ARG C 1 71  ? -22.988 -1.538  9.049   1    38.67  ? 241 ARG B NE  1 
ATOM   5128 C  CZ  . ARG C 1 71  ? -22.278 -2.551  9.526   1    38.5   ? 241 ARG B CZ  1 
ATOM   5129 N  NH1 . ARG C 1 71  ? -21.348 -3.116  8.779   1    32.75  ? 241 ARG B NH1 1 
ATOM   5130 N  NH2 . ARG C 1 71  ? -22.508 -3.004  10.746  1    37.51  ? 241 ARG B NH2 1 
ATOM   5131 N  N   . PHE C 1 72  ? -23.471 3.707   10.673  1    38.16  ? 242 PHE B N   1 
ATOM   5132 C  CA  . PHE C 1 72  ? -23.05  4.555   11.772  1    36.78  ? 242 PHE B CA  1 
ATOM   5133 C  C   . PHE C 1 72  ? -23.985 5.756   11.882  1    37.77  ? 242 PHE B C   1 
ATOM   5134 O  O   . PHE C 1 72  ? -24.388 6.105   12.983  1    39.08  ? 242 PHE B O   1 
ATOM   5135 C  CB  . PHE C 1 72  ? -21.604 5.004   11.574  1    34.71  ? 242 PHE B CB  1 
ATOM   5136 C  CG  . PHE C 1 72  ? -21.048 5.8     12.74   1    38.4   ? 242 PHE B CG  1 
ATOM   5137 C  CD1 . PHE C 1 72  ? -20.478 5.13    13.832  1    38.74  ? 242 PHE B CD1 1 
ATOM   5138 C  CD2 . PHE C 1 72  ? -21.079 7.204   12.745  1    37.86  ? 242 PHE B CD2 1 
ATOM   5139 C  CE1 . PHE C 1 72  ? -19.963 5.845   14.908  1    38.03  ? 242 PHE B CE1 1 
ATOM   5140 C  CE2 . PHE C 1 72  ? -20.551 7.914   13.816  1    37.73  ? 242 PHE B CE2 1 
ATOM   5141 C  CZ  . PHE C 1 72  ? -19.993 7.233   14.892  1    39.43  ? 242 PHE B CZ  1 
ATOM   5142 N  N   . LEU C 1 73  ? -24.322 6.39    10.747  1    37.91  ? 243 LEU B N   1 
ATOM   5143 C  CA  . LEU C 1 73  ? -25.085 7.629   10.783  1    41.65  ? 243 LEU B CA  1 
ATOM   5144 C  C   . LEU C 1 73  ? -26.556 7.361   11.082  1    44.24  ? 243 LEU B C   1 
ATOM   5145 O  O   . LEU C 1 73  ? -27.289 8.311   11.342  1    53.07  ? 243 LEU B O   1 
ATOM   5146 C  CB  . LEU C 1 73  ? -24.941 8.39    9.469   1    44.21  ? 243 LEU B CB  1 
ATOM   5147 C  CG  . LEU C 1 73  ? -23.544 8.924   9.157   1    45.23  ? 243 LEU B CG  1 
ATOM   5148 C  CD1 . LEU C 1 73  ? -23.553 9.508   7.765   1    39.44  ? 243 LEU B CD1 1 
ATOM   5149 C  CD2 . LEU C 1 73  ? -23.116 9.924   10.232  1    47.07  ? 243 LEU B CD2 1 
ATOM   5150 N  N   . SER C 1 74  ? -26.965 6.085   11.069  1    42.11  ? 244 SER B N   1 
ATOM   5151 C  CA  . SER C 1 74  ? -28.317 5.668   11.418  1    42.51  ? 244 SER B CA  1 
ATOM   5152 C  C   . SER C 1 74  ? -28.577 5.771   12.928  1    45.37  ? 244 SER B C   1 
ATOM   5153 O  O   . SER C 1 74  ? -29.742 5.955   13.319  1    44.13  ? 244 SER B O   1 
ATOM   5154 C  CB  . SER C 1 74  ? -28.61  4.275   10.917  1    42.46  ? 244 SER B CB  1 
ATOM   5155 O  OG  . SER C 1 74  ? -28.53  4.195   9.499   1    46.71  ? 244 SER B OG  1 
ATOM   5156 N  N   . SER C 1 75  ? -27.513 5.657   13.767  1    43.13  ? 245 SER B N   1 
ATOM   5157 C  CA  . SER C 1 75  ? -27.7   5.734   15.211  1    43.73  ? 245 SER B CA  1 
ATOM   5158 C  C   . SER C 1 75  ? -26.915 6.861   15.889  1    44.75  ? 245 SER B C   1 
ATOM   5159 O  O   . SER C 1 75  ? -27.167 7.154   17.06   1    45.18  ? 245 SER B O   1 
ATOM   5160 C  CB  . SER C 1 75  ? -27.49  4.422   15.883  1    42.23  ? 245 SER B CB  1 
ATOM   5161 O  OG  . SER C 1 75  ? -26.113 4.142   15.96   1    46.05  ? 245 SER B OG  1 
ATOM   5162 N  N   . MET C 1 76  ? -25.993 7.524   15.168  1    44.68  ? 246 MET B N   1 
ATOM   5163 C  CA  . MET C 1 76  ? -25.153 8.56    15.779  1    41.11  ? 246 MET B CA  1 
ATOM   5164 C  C   . MET C 1 76  ? -25.275 9.86    14.99   1    41.9   ? 246 MET B C   1 
ATOM   5165 O  O   . MET C 1 76  ? -25.048 9.864   13.778  1    43.82  ? 246 MET B O   1 
ATOM   5166 C  CB  . MET C 1 76  ? -23.681 8.141   15.725  1    36.99  ? 246 MET B CB  1 
ATOM   5167 C  CG  . MET C 1 76  ? -23.421 6.801   16.364  1    37.09  ? 246 MET B CG  1 
ATOM   5168 S  SD  . MET C 1 76  ? -23.541 6.856   18.16   1    42.02  ? 246 MET B SD  1 
ATOM   5169 C  CE  . MET C 1 76  ? -22.137 7.888   18.608  1    39.73  ? 246 MET B CE  1 
ATOM   5170 N  N   . SER C 1 77  ? -25.675 10.935  15.672  1    41.51  ? 247 SER B N   1 
ATOM   5171 C  CA  . SER C 1 77  ? -25.676 12.263  15.083  1    43.91  ? 247 SER B CA  1 
ATOM   5172 C  C   . SER C 1 77  ? -24.243 12.767  14.966  1    46.11  ? 247 SER B C   1 
ATOM   5173 O  O   . SER C 1 77  ? -23.446 12.551  15.893  1    47.4   ? 247 SER B O   1 
ATOM   5174 C  CB  . SER C 1 77  ? -26.445 13.243  15.926  1    45.84  ? 247 SER B CB  1 
ATOM   5175 O  OG  . SER C 1 77  ? -27.831 12.958  15.898  1    49.51  ? 247 SER B OG  1 
ATOM   5176 N  N   . VAL C 1 78  ? -23.974 13.494  13.86   1    44.73  ? 248 VAL B N   1 
ATOM   5177 C  CA  . VAL C 1 78  ? -22.636 13.982  13.556  1    44.16  ? 248 VAL B CA  1 
ATOM   5178 C  C   . VAL C 1 78  ? -22.647 15.406  13.004  1    47.18  ? 248 VAL B C   1 
ATOM   5179 O  O   . VAL C 1 78  ? -23.391 15.701  12.074  1    51.6   ? 248 VAL B O   1 
ATOM   5180 C  CB  . VAL C 1 78  ? -22.018 13.016  12.542  1    42.39  ? 248 VAL B CB  1 
ATOM   5181 C  CG1 . VAL C 1 78  ? -20.639 13.494  12.137  1    42.48  ? 248 VAL B CG1 1 
ATOM   5182 C  CG2 . VAL C 1 78  ? -21.948 11.605  13.115  1    43.8   ? 248 VAL B CG2 1 
ATOM   5183 N  N   . LEU C 1 79  ? -21.802 16.283  13.578  1    48.46  ? 249 LEU B N   1 
ATOM   5184 C  CA  . LEU C 1 79  ? -21.567 17.635  13.073  1    48.35  ? 249 LEU B CA  1 
ATOM   5185 C  C   . LEU C 1 79  ? -20.81  17.587  11.741  1    47.46  ? 249 LEU B C   1 
ATOM   5186 O  O   . LEU C 1 79  ? -19.915 16.76   11.53   1    43.94  ? 249 LEU B O   1 
ATOM   5187 C  CB  . LEU C 1 79  ? -20.814 18.463  14.115  1    50.11  ? 249 LEU B CB  1 
ATOM   5188 C  CG  . LEU C 1 79  ? -21.594 18.928  15.348  1    56.7   ? 249 LEU B CG  1 
ATOM   5189 C  CD1 . LEU C 1 79  ? -20.91  20.12   15.99   1    55.21  ? 249 LEU B CD1 1 
ATOM   5190 C  CD2 . LEU C 1 79  ? -23.043 19.278  15.02   1    59.66  ? 249 LEU B CD2 1 
ATOM   5191 N  N   . ARG C 1 80  ? -21.15  18.509  10.839  1    50.53  ? 250 ARG B N   1 
ATOM   5192 C  CA  . ARG C 1 80  ? -20.628 18.459  9.475   1    51.68  ? 250 ARG B CA  1 
ATOM   5193 C  C   . ARG C 1 80  ? -19.096 18.4    9.5     1    54.18  ? 250 ARG B C   1 
ATOM   5194 O  O   . ARG C 1 80  ? -18.503 17.714  8.654   1    50.01  ? 250 ARG B O   1 
ATOM   5195 C  CB  . ARG C 1 80  ? -21.158 19.626  8.636   1    51.68  ? 250 ARG B CB  1 
ATOM   5196 C  CG  . ARG C 1 80  ? -20.581 20.962  9.087   1    55.56  ? 250 ARG B CG  1 
ATOM   5197 C  CD  . ARG C 1 80  ? -21.231 22.137  8.403   1    56.94  ? 250 ARG B CD  1 
ATOM   5198 N  NE  . ARG C 1 80  ? -22.661 22.113  8.72    1    62.66  ? 250 ARG B NE  1 
ATOM   5199 C  CZ  . ARG C 1 80  ? -23.582 22.941  8.216   1    67.97  ? 250 ARG B CZ  1 
ATOM   5200 N  NH1 . ARG C 1 80  ? -23.29  23.839  7.286   1    65.02  ? 250 ARG B NH1 1 
ATOM   5201 N  NH2 . ARG C 1 80  ? -24.821 22.856  8.648   1    68.98  ? 250 ARG B NH2 1 
ATOM   5202 N  N   . GLY C 1 81  ? -18.49  19.077  10.504  1    52.15  ? 251 GLY B N   1 
ATOM   5203 C  CA  . GLY C 1 81  ? -17.052 19.128  10.734  1    47.01  ? 251 GLY B CA  1 
ATOM   5204 C  C   . GLY C 1 81  ? -16.43  17.761  11.028  1    47.76  ? 251 GLY B C   1 
ATOM   5205 O  O   . GLY C 1 81  ? -15.205 17.628  10.982  1    46.26  ? 251 GLY B O   1 
ATOM   5206 N  N   . LYS C 1 82  ? -17.265 16.748  11.331  1    45.65  ? 252 LYS B N   1 
ATOM   5207 C  CA  . LYS C 1 82  ? -16.754 15.453  11.746  1    42.25  ? 252 LYS B CA  1 
ATOM   5208 C  C   . LYS C 1 82  ? -17.159 14.334  10.796  1    42.47  ? 252 LYS B C   1 
ATOM   5209 O  O   . LYS C 1 82  ? -16.767 13.182  10.99   1    44.95  ? 252 LYS B O   1 
ATOM   5210 C  CB  . LYS C 1 82  ? -17.231 15.158  13.164  1    40.97  ? 252 LYS B CB  1 
ATOM   5211 C  CG  . LYS C 1 82  ? -16.654 16.085  14.23   1    43.41  ? 252 LYS B CG  1 
ATOM   5212 C  CD  . LYS C 1 82  ? -15.145 15.89   14.33   1    43.29  ? 252 LYS B CD  1 
ATOM   5213 C  CE  . LYS C 1 82  ? -14.547 16.071  15.689  1    43.57  ? 252 LYS B CE  1 
ATOM   5214 N  NZ  . LYS C 1 82  ? -14.681 17.507  15.952  1    45.73  ? 252 LYS B NZ  1 
ATOM   5215 N  N   . LEU C 1 83  ? -17.951 14.658  9.776   1    42.15  ? 253 LEU B N   1 
ATOM   5216 C  CA  . LEU C 1 83  ? -18.398 13.636  8.849   1    41.49  ? 253 LEU B CA  1 
ATOM   5217 C  C   . LEU C 1 83  ? -17.183 12.959  8.202   1    44.76  ? 253 LEU B C   1 
ATOM   5218 O  O   . LEU C 1 83  ? -17.182 11.739  7.978   1    47.19  ? 253 LEU B O   1 
ATOM   5219 C  CB  . LEU C 1 83  ? -19.286 14.311  7.808   1    38.95  ? 253 LEU B CB  1 
ATOM   5220 C  CG  . LEU C 1 83  ? -19.954 13.398  6.77    1    37.21  ? 253 LEU B CG  1 
ATOM   5221 C  CD1 . LEU C 1 83  ? -20.679 12.193  7.418   1    34     ? 253 LEU B CD1 1 
ATOM   5222 C  CD2 . LEU C 1 83  ? -20.933 14.237  5.946   1    34.85  ? 253 LEU B CD2 1 
ATOM   5223 N  N   . GLN C 1 84  ? -16.153 13.762  7.883   1    44     ? 254 GLN B N   1 
ATOM   5224 C  CA  . GLN C 1 84  ? -14.988 13.241  7.182   1    44.53  ? 254 GLN B CA  1 
ATOM   5225 C  C   . GLN C 1 84  ? -14.19  12.319  8.109   1    42.02  ? 254 GLN B C   1 
ATOM   5226 O  O   . GLN C 1 84  ? -13.606 11.329  7.665   1    39.9   ? 254 GLN B O   1 
ATOM   5227 C  CB  . GLN C 1 84  ? -14.161 14.347  6.526   1    46.14  ? 254 GLN B CB  1 
ATOM   5228 C  CG  . GLN C 1 84  ? -12.919 13.82   5.818   1    46.37  ? 254 GLN B CG  1 
ATOM   5229 C  CD  . GLN C 1 84  ? -12.146 14.87   5.053   1    45.29  ? 254 GLN B CD  1 
ATOM   5230 O  OE1 . GLN C 1 84  ? -11.786 14.648  3.903   1    47.08  ? 254 GLN B OE1 1 
ATOM   5231 N  NE2 . GLN C 1 84  ? -11.834 15.995  5.668   1    44.52  ? 254 GLN B NE2 1 
ATOM   5232 N  N   . LEU C 1 85  ? -14.209 12.639  9.405   1    41.61  ? 255 LEU B N   1 
ATOM   5233 C  CA  . LEU C 1 85  ? -13.563 11.806  10.403  1    40.38  ? 255 LEU B CA  1 
ATOM   5234 C  C   . LEU C 1 85  ? -14.219 10.43   10.45   1    39.73  ? 255 LEU B C   1 
ATOM   5235 O  O   . LEU C 1 85  ? -13.516 9.418   10.556  1    39.99  ? 255 LEU B O   1 
ATOM   5236 C  CB  . LEU C 1 85  ? -13.56  12.478  11.77   1    39.23  ? 255 LEU B CB  1 
ATOM   5237 C  CG  . LEU C 1 85  ? -12.896 11.662  12.881  1    40.26  ? 255 LEU B CG  1 
ATOM   5238 C  CD1 . LEU C 1 85  ? -11.5   11.192  12.507  1    39.28  ? 255 LEU B CD1 1 
ATOM   5239 C  CD2 . LEU C 1 85  ? -12.871 12.492  14.148  1    41.64  ? 255 LEU B CD2 1 
ATOM   5240 N  N   . VAL C 1 86  ? -15.557 10.417  10.398  1    37.52  ? 256 VAL B N   1 
ATOM   5241 C  CA  . VAL C 1 86  ? -16.308 9.172   10.406  1    38.05  ? 256 VAL B CA  1 
ATOM   5242 C  C   . VAL C 1 86  ? -15.932 8.374   9.156   1    39.05  ? 256 VAL B C   1 
ATOM   5243 O  O   . VAL C 1 86  ? -15.661 7.177   9.239   1    36.58  ? 256 VAL B O   1 
ATOM   5244 C  CB  . VAL C 1 86  ? -17.828 9.407   10.453  1    37.81  ? 256 VAL B CB  1 
ATOM   5245 C  CG1 . VAL C 1 86  ? -18.574 8.107   10.256  1    34.97  ? 256 VAL B CG1 1 
ATOM   5246 C  CG2 . VAL C 1 86  ? -18.269 10.106  11.732  1    38.16  ? 256 VAL B CG2 1 
ATOM   5247 N  N   . GLY C 1 87  ? -15.923 9.057   8.002   1    39.84  ? 257 GLY B N   1 
ATOM   5248 C  CA  . GLY C 1 87  ? -15.61  8.425   6.732   1    41.27  ? 257 GLY B CA  1 
ATOM   5249 C  C   . GLY C 1 87  ? -14.181 7.884   6.672   1    45.08  ? 257 GLY B C   1 
ATOM   5250 O  O   . GLY C 1 87  ? -13.947 6.795   6.156   1    43.87  ? 257 GLY B O   1 
ATOM   5251 N  N   . THR C 1 88  ? -13.226 8.646   7.21    1    45.2   ? 258 THR B N   1 
ATOM   5252 C  CA  . THR C 1 88  ? -11.844 8.214   7.206   1    42.94  ? 258 THR B CA  1 
ATOM   5253 C  C   . THR C 1 88  ? -11.735 6.905   7.987   1    43.75  ? 258 THR B C   1 
ATOM   5254 O  O   . THR C 1 88  ? -11.133 5.959   7.5     1    44.51  ? 258 THR B O   1 
ATOM   5255 C  CB  . THR C 1 88  ? -10.959 9.319   7.775   1    43.09  ? 258 THR B CB  1 
ATOM   5256 O  OG1 . THR C 1 88  ? -11.151 10.444  6.915   1    48.64  ? 258 THR B OG1 1 
ATOM   5257 C  CG2 . THR C 1 88  ? -9.496  8.913   7.823   1    43.11  ? 258 THR B CG2 1 
ATOM   5258 N  N   . ALA C 1 89  ? -12.334 6.849   9.182   1    43.19  ? 259 ALA B N   1 
ATOM   5259 C  CA  . ALA C 1 89  ? -12.225 5.679   10.043  1    41.78  ? 259 ALA B CA  1 
ATOM   5260 C  C   . ALA C 1 89  ? -12.928 4.494   9.376   1    39.95  ? 259 ALA B C   1 
ATOM   5261 O  O   . ALA C 1 89  ? -12.504 3.346   9.49    1    40.09  ? 259 ALA B O   1 
ATOM   5262 C  CB  . ALA C 1 89  ? -12.808 5.963   11.424  1    39.23  ? 259 ALA B CB  1 
ATOM   5263 N  N   . ALA C 1 90  ? -14.035 4.774   8.685   1    37.3   ? 260 ALA B N   1 
ATOM   5264 C  CA  . ALA C 1 90  ? -14.757 3.705   8.033   1    35.77  ? 260 ALA B CA  1 
ATOM   5265 C  C   . ALA C 1 90  ? -13.842 3.064   6.978   1    39.54  ? 260 ALA B C   1 
ATOM   5266 O  O   . ALA C 1 90  ? -13.763 1.838   6.894   1    39.54  ? 260 ALA B O   1 
ATOM   5267 C  CB  . ALA C 1 90  ? -16.01  4.277   7.444   1    33.14  ? 260 ALA B CB  1 
ATOM   5268 N  N   . MET C 1 91  ? -13.145 3.908   6.195   1    37.88  ? 261 MET B N   1 
ATOM   5269 C  CA  . MET C 1 91  ? -12.283 3.474   5.109   1    39.32  ? 261 MET B CA  1 
ATOM   5270 C  C   . MET C 1 91  ? -11.096 2.669   5.668   1    42.93  ? 261 MET B C   1 
ATOM   5271 O  O   . MET C 1 91  ? -10.678 1.669   5.076   1    43.59  ? 261 MET B O   1 
ATOM   5272 C  CB  . MET C 1 91  ? -11.803 4.687   4.304   1    39.09  ? 261 MET B CB  1 
ATOM   5273 C  CG  . MET C 1 91  ? -11.3   4.37    2.893   1    43.49  ? 261 MET B CG  1 
ATOM   5274 S  SD  . MET C 1 91  ? -12.523 3.566   1.827   1    46.87  ? 261 MET B SD  1 
ATOM   5275 C  CE  . MET C 1 91  ? -11.93  4.009   0.196   1    47.55  ? 261 MET B CE  1 
ATOM   5276 N  N   . LEU C 1 92  ? -10.582 3.089   6.83    1    37.12  ? 262 LEU B N   1 
ATOM   5277 C  CA  . LEU C 1 92  ? -9.522  2.374   7.513   1    41.21  ? 262 LEU B CA  1 
ATOM   5278 C  C   . LEU C 1 92  ? -9.987  0.96    7.905   1    42.74  ? 262 LEU B C   1 
ATOM   5279 O  O   . LEU C 1 92  ? -9.254  -0.026  7.714   1    43.42  ? 262 LEU B O   1 
ATOM   5280 C  CB  . LEU C 1 92  ? -9.067  3.196   8.719   1    37     ? 262 LEU B CB  1 
ATOM   5281 C  CG  . LEU C 1 92  ? -8.015  2.543   9.619   1    37.42  ? 262 LEU B CG  1 
ATOM   5282 C  CD1 . LEU C 1 92  ? -6.718  2.223   8.873   1    36.7   ? 262 LEU B CD1 1 
ATOM   5283 C  CD2 . LEU C 1 92  ? -7.726  3.405   10.839  1    36.04  ? 262 LEU B CD2 1 
ATOM   5284 N  N   . LEU C 1 93  ? -11.214 0.867   8.431   1    35.7   ? 263 LEU B N   1 
ATOM   5285 C  CA  . LEU C 1 93  ? -11.739 -0.405  8.88    1    36.02  ? 263 LEU B CA  1 
ATOM   5286 C  C   . LEU C 1 93  ? -11.972 -1.297  7.673   1    37.39  ? 263 LEU B C   1 
ATOM   5287 O  O   . LEU C 1 93  ? -11.631 -2.48   7.687   1    40.82  ? 263 LEU B O   1 
ATOM   5288 C  CB  . LEU C 1 93  ? -13.021 -0.157  9.667   1    38.14  ? 263 LEU B CB  1 
ATOM   5289 C  CG  . LEU C 1 93  ? -12.826 0.331   11.113  1    38.69  ? 263 LEU B CG  1 
ATOM   5290 C  CD1 . LEU C 1 93  ? -14.175 0.589   11.807  1    36.53  ? 263 LEU B CD1 1 
ATOM   5291 C  CD2 . LEU C 1 93  ? -11.998 -0.677  11.894  1    34.49  ? 263 LEU B CD2 1 
ATOM   5292 N  N   . ALA C 1 94  ? -12.542 -0.708  6.622   1    38.36  ? 264 ALA B N   1 
ATOM   5293 C  CA  . ALA C 1 94  ? -12.834 -1.444  5.402   1    38.41  ? 264 ALA B CA  1 
ATOM   5294 C  C   . ALA C 1 94  ? -11.54  -2.027  4.851   1    37.48  ? 264 ALA B C   1 
ATOM   5295 O  O   . ALA C 1 94  ? -11.497 -3.186  4.486   1    37.46  ? 264 ALA B O   1 
ATOM   5296 C  CB  . ALA C 1 94  ? -13.489 -0.539  4.395   1    39     ? 264 ALA B CB  1 
ATOM   5297 N  N   . SER C 1 95  ? -10.494 -1.197  4.796   1    39.47  ? 265 SER B N   1 
ATOM   5298 C  CA  . SER C 1 95  ? -9.175  -1.575  4.324   1    37.02  ? 265 SER B CA  1 
ATOM   5299 C  C   . SER C 1 95  ? -8.61   -2.726  5.154   1    36.97  ? 265 SER B C   1 
ATOM   5300 O  O   . SER C 1 95  ? -8.176  -3.732  4.593   1    38.9   ? 265 SER B O   1 
ATOM   5301 C  CB  . SER C 1 95  ? -8.232  -0.411  4.358   1    39.2   ? 265 SER B CB  1 
ATOM   5302 O  OG  . SER C 1 95  ? -8.602  0.596   3.433   1    41.87  ? 265 SER B OG  1 
ATOM   5303 N  N   . LYS C 1 96  ? -8.565  -2.57   6.48    1    34.17  ? 266 LYS B N   1 
ATOM   5304 C  CA  . LYS C 1 96  ? -8.018  -3.65   7.287   1    37.18  ? 266 LYS B CA  1 
ATOM   5305 C  C   . LYS C 1 96  ? -8.812  -4.946  7.087   1    38     ? 266 LYS B C   1 
ATOM   5306 O  O   . LYS C 1 96  ? -8.241  -6.028  7.156   1    40.41  ? 266 LYS B O   1 
ATOM   5307 C  CB  . LYS C 1 96  ? -8.022  -3.273  8.767   1    37.58  ? 266 LYS B CB  1 
ATOM   5308 C  CG  . LYS C 1 96  ? -6.965  -2.286  9.211   1    36.6   ? 266 LYS B CG  1 
ATOM   5309 C  CD  . LYS C 1 96  ? -7.366  -1.633  10.532  1    38.19  ? 266 LYS B CD  1 
ATOM   5310 C  CE  . LYS C 1 96  ? -6.207  -0.991  11.236  1    39.74  ? 266 LYS B CE  1 
ATOM   5311 N  NZ  . LYS C 1 96  ? -6.481  -0.71   12.642  1    38.01  ? 266 LYS B NZ  1 
ATOM   5312 N  N   . PHE C 1 97  ? -10.125 -4.848  6.827   1    36.99  ? 267 PHE B N   1 
ATOM   5313 C  CA  . PHE C 1 97  ? -10.928 -6.042  6.655   1    35.83  ? 267 PHE B CA  1 
ATOM   5314 C  C   . PHE C 1 97  ? -10.631 -6.705  5.314   1    35.88  ? 267 PHE B C   1 
ATOM   5315 O  O   . PHE C 1 97  ? -10.435 -7.918  5.259   1    36.31  ? 267 PHE B O   1 
ATOM   5316 C  CB  . PHE C 1 97  ? -12.426 -5.738  6.675   1    36.46  ? 267 PHE B CB  1 
ATOM   5317 C  CG  . PHE C 1 97  ? -13.317 -6.973  6.555   1    36.92  ? 267 PHE B CG  1 
ATOM   5318 C  CD1 . PHE C 1 97  ? -13.555 -7.797  7.655   1    37.6   ? 267 PHE B CD1 1 
ATOM   5319 C  CD2 . PHE C 1 97  ? -13.924 -7.307  5.35    1    36.39  ? 267 PHE B CD2 1 
ATOM   5320 C  CE1 . PHE C 1 97  ? -14.378 -8.915  7.545   1    40.09  ? 267 PHE B CE1 1 
ATOM   5321 C  CE2 . PHE C 1 97  ? -14.748 -8.425  5.242   1    37.14  ? 267 PHE B CE2 1 
ATOM   5322 C  CZ  . PHE C 1 97  ? -14.972 -9.232  6.34    1    39.68  ? 267 PHE B CZ  1 
ATOM   5323 N  N   . GLU C 1 98  ? -10.614 -5.893  4.252   1    33.33  ? 268 GLU B N   1 
ATOM   5324 C  CA  . GLU C 1 98  ? -10.7   -6.409  2.896   1    34.63  ? 268 GLU B CA  1 
ATOM   5325 C  C   . GLU C 1 98  ? -9.362  -6.436  2.144   1    34.15  ? 268 GLU B C   1 
ATOM   5326 O  O   . GLU C 1 98  ? -9.219  -7.256  1.243   1    35.57  ? 268 GLU B O   1 
ATOM   5327 C  CB  . GLU C 1 98  ? -11.742 -5.62   2.11    1    33.06  ? 268 GLU B CB  1 
ATOM   5328 C  CG  . GLU C 1 98  ? -12.101 -6.302  0.793   1    35.95  ? 268 GLU B CG  1 
ATOM   5329 C  CD  . GLU C 1 98  ? -12.791 -7.658  0.951   1    37.5   ? 268 GLU B CD  1 
ATOM   5330 O  OE1 . GLU C 1 98  ? -13.438 -7.893  1.977   1    38.81  ? 268 GLU B OE1 1 
ATOM   5331 O  OE2 . GLU C 1 98  ? -12.707 -8.5    0.052   1    38.95  ? 268 GLU B OE2 1 
ATOM   5332 N  N   . GLU C 1 99  ? -8.391  -5.589  2.52    1    33.06  ? 269 GLU B N   1 
ATOM   5333 C  CA  . GLU C 1 99  ? -7.148  -5.45   1.771   1    36.05  ? 269 GLU B CA  1 
ATOM   5334 C  C   . GLU C 1 99  ? -6.037  -6.403  2.225   1    41.47  ? 269 GLU B C   1 
ATOM   5335 O  O   . GLU C 1 99  ? -5.817  -6.658  3.415   1    43.6   ? 269 GLU B O   1 
ATOM   5336 C  CB  . GLU C 1 99  ? -6.616  -4.017  1.83    1    36.66  ? 269 GLU B CB  1 
ATOM   5337 C  CG  . GLU C 1 99  ? -7.536  -2.996  1.16    1    38.01  ? 269 GLU B CG  1 
ATOM   5338 C  CD  . GLU C 1 99  ? -7.613  -3.007  -0.362  1    39.82  ? 269 GLU B CD  1 
ATOM   5339 O  OE1 . GLU C 1 99  ? -6.626  -3.508  -0.993  1    44.68  ? 269 GLU B OE1 1 
ATOM   5340 O  OE2 . GLU C 1 99  ? -8.658  -2.556  -0.91   1    34.98  ? 269 GLU B OE2 1 
ATOM   5341 N  N   . ILE C 1 100 ? -5.265  -6.869  1.235   1    41.53  ? 270 ILE B N   1 
ATOM   5342 C  CA  . ILE C 1 100 ? -4.017  -7.554  1.492   1    41.63  ? 270 ILE B CA  1 
ATOM   5343 C  C   . ILE C 1 100 ? -3.066  -6.549  2.129   1    44.97  ? 270 ILE B C   1 
ATOM   5344 O  O   . ILE C 1 100 ? -2.43   -6.859  3.123   1    48.12  ? 270 ILE B O   1 
ATOM   5345 C  CB  . ILE C 1 100 ? -3.411  -8.112  0.188   1    42.91  ? 270 ILE B CB  1 
ATOM   5346 C  CG1 . ILE C 1 100 ? -4.37   -9.051  -0.545  1    37.07  ? 270 ILE B CG1 1 
ATOM   5347 C  CG2 . ILE C 1 100 ? -2.052  -8.777  0.459   1    40.33  ? 270 ILE B CG2 1 
ATOM   5348 C  CD1 . ILE C 1 100 ? -3.86   -9.5    -1.894  1    36.54  ? 270 ILE B CD1 1 
ATOM   5349 N  N   . TYR C 1 101 ? -2.969  -5.356  1.534   1    46.39  ? 271 TYR B N   1 
ATOM   5350 C  CA  . TYR C 1 101 ? -2.007  -4.357  1.973   1    51.12  ? 271 TYR B CA  1 
ATOM   5351 C  C   . TYR C 1 101 ? -2.719  -3.06   2.339   1    52.96  ? 271 TYR B C   1 
ATOM   5352 O  O   . TYR C 1 101 ? -2.678  -2.092  1.584   1    57.24  ? 271 TYR B O   1 
ATOM   5353 C  CB  . TYR C 1 101 ? -0.925  -4.137  0.913   1    52.26  ? 271 TYR B CB  1 
ATOM   5354 C  CG  . TYR C 1 101 ? -0.026  -5.354  0.748   1    57.61  ? 271 TYR B CG  1 
ATOM   5355 C  CD1 . TYR C 1 101 ? 0.763   -5.782  1.815   1    56.57  ? 271 TYR B CD1 1 
ATOM   5356 C  CD2 . TYR C 1 101 ? 0.051   -6.059  -0.46   1    56.82  ? 271 TYR B CD2 1 
ATOM   5357 C  CE1 . TYR C 1 101 ? 1.591   -6.884  1.691   1    57.5   ? 271 TYR B CE1 1 
ATOM   5358 C  CE2 . TYR C 1 101 ? 0.894   -7.154  -0.598  1    56.22  ? 271 TYR B CE2 1 
ATOM   5359 C  CZ  . TYR C 1 101 ? 1.65    -7.569  0.487   1    58.88  ? 271 TYR B CZ  1 
ATOM   5360 O  OH  . TYR C 1 101 ? 2.477   -8.647  0.418   1    68.01  ? 271 TYR B OH  1 
ATOM   5361 N  N   . PRO C 1 102 ? -3.371  -2.978  3.522   1    52.93  ? 272 PRO B N   1 
ATOM   5362 C  CA  . PRO C 1 102 ? -4.127  -1.774  3.883   1    47.86  ? 272 PRO B CA  1 
ATOM   5363 C  C   . PRO C 1 102 ? -3.138  -0.619  4.06    1    47.64  ? 272 PRO B C   1 
ATOM   5364 O  O   . PRO C 1 102 ? -2.007  -0.803  4.534   1    47.14  ? 272 PRO B O   1 
ATOM   5365 C  CB  . PRO C 1 102 ? -4.822  -2.186  5.188   1    46.66  ? 272 PRO B CB  1 
ATOM   5366 C  CG  . PRO C 1 102 ? -3.878  -3.205  5.788   1    47.85  ? 272 PRO B CG  1 
ATOM   5367 C  CD  . PRO C 1 102 ? -3.327  -3.985  4.597   1    50.31  ? 272 PRO B CD  1 
ATOM   5368 N  N   . PRO C 1 103 ? -3.492  0.613   3.639   1    46.17  ? 273 PRO B N   1 
ATOM   5369 C  CA  . PRO C 1 103 ? -2.583  1.743   3.835   1    47.18  ? 273 PRO B CA  1 
ATOM   5370 C  C   . PRO C 1 103 ? -2.479  1.927   5.347   1    49.66  ? 273 PRO B C   1 
ATOM   5371 O  O   . PRO C 1 103 ? -3.372  1.557   6.103   1    46.25  ? 273 PRO B O   1 
ATOM   5372 C  CB  . PRO C 1 103 ? -3.259  2.931   3.133   1    43.76  ? 273 PRO B CB  1 
ATOM   5373 C  CG  . PRO C 1 103 ? -4.402  2.323   2.339   1    41.21  ? 273 PRO B CG  1 
ATOM   5374 C  CD  . PRO C 1 103 ? -4.753  0.99    2.983   1    42.67  ? 273 PRO B CD  1 
ATOM   5375 N  N   . GLU C 1 104 ? -1.36   2.493   5.783   1    53.58  ? 274 GLU B N   1 
ATOM   5376 C  CA  . GLU C 1 104 ? -1.14   2.767   7.188   1    57.45  ? 274 GLU B CA  1 
ATOM   5377 C  C   . GLU C 1 104 ? -2.042  3.902   7.667   1    56.53  ? 274 GLU B C   1 
ATOM   5378 O  O   . GLU C 1 104 ? -2.532  4.711   6.885   1    53.1   ? 274 GLU B O   1 
ATOM   5379 C  CB  . GLU C 1 104 ? 0.306   3.237   7.296   1    69.65  ? 274 GLU B CB  1 
ATOM   5380 C  CG  . GLU C 1 104 ? 1.306   2.174   6.849   1    80.03  ? 274 GLU B CG  1 
ATOM   5381 C  CD  . GLU C 1 104 ? 2.714   2.729   6.73    1    96.4   ? 274 GLU B CD  1 
ATOM   5382 O  OE1 . GLU C 1 104 ? 3.638   1.894   6.612   1    112.53 ? 274 GLU B OE1 1 
ATOM   5383 O  OE2 . GLU C 1 104 ? 2.878   3.976   6.734   1    97.42  ? 274 GLU B OE2 1 
ATOM   5384 N  N   . VAL C 1 105 ? -2.233  3.953   8.984   1    57.62  ? 275 VAL B N   1 
ATOM   5385 C  CA  . VAL C 1 105 ? -3.027  4.975   9.652   1    59.82  ? 275 VAL B CA  1 
ATOM   5386 C  C   . VAL C 1 105 ? -2.509  6.372   9.304   1    59.46  ? 275 VAL B C   1 
ATOM   5387 O  O   . VAL C 1 105 ? -3.303  7.307   9.207   1    57.37  ? 275 VAL B O   1 
ATOM   5388 C  CB  . VAL C 1 105 ? -3.033  4.761   11.179  1    58.33  ? 275 VAL B CB  1 
ATOM   5389 C  CG1 . VAL C 1 105 ? -3.746  5.88    11.906  1    56.9   ? 275 VAL B CG1 1 
ATOM   5390 C  CG2 . VAL C 1 105 ? -3.662  3.43    11.548  1    61.15  ? 275 VAL B CG2 1 
ATOM   5391 N  N   . ALA C 1 106 ? -1.189  6.516   9.125   1    57.88  ? 276 ALA B N   1 
ATOM   5392 C  CA  . ALA C 1 106 ? -0.625  7.829   8.849   1    55.32  ? 276 ALA B CA  1 
ATOM   5393 C  C   . ALA C 1 106 ? -1.051  8.323   7.461   1    54.65  ? 276 ALA B C   1 
ATOM   5394 O  O   . ALA C 1 106 ? -1.068  9.52    7.211   1    58.42  ? 276 ALA B O   1 
ATOM   5395 C  CB  . ALA C 1 106 ? 0.872   7.803   9.02    1    53.2   ? 276 ALA B CB  1 
ATOM   5396 N  N   . GLU C 1 107 ? -1.391  7.404   6.553   1    50.66  ? 277 GLU B N   1 
ATOM   5397 C  CA  . GLU C 1 107 ? -1.74   7.801   5.205   1    54.37  ? 277 GLU B CA  1 
ATOM   5398 C  C   . GLU C 1 107 ? -3.188  8.272   5.205   1    53.66  ? 277 GLU B C   1 
ATOM   5399 O  O   . GLU C 1 107 ? -3.556  9.2     4.491   1    55.78  ? 277 GLU B O   1 
ATOM   5400 C  CB  . GLU C 1 107 ? -1.468  6.667   4.22    1    57.62  ? 277 GLU B CB  1 
ATOM   5401 C  CG  . GLU C 1 107 ? 0.024   6.475   3.97    1    68.85  ? 277 GLU B CG  1 
ATOM   5402 C  CD  . GLU C 1 107 ? 0.411   5.471   2.896   1    82.97  ? 277 GLU B CD  1 
ATOM   5403 O  OE1 . GLU C 1 107 ? 1.132   5.935   1.972   1    89.78  ? 277 GLU B OE1 1 
ATOM   5404 O  OE2 . GLU C 1 107 ? 0.01    4.27    2.963   1    78.14  ? 277 GLU B OE2 1 
ATOM   5405 N  N   . PHE C 1 108 ? -4.003  7.63    6.037   1    52.03  ? 278 PHE B N   1 
ATOM   5406 C  CA  . PHE C 1 108 ? -5.362  8.093   6.255   1    50.07  ? 278 PHE B CA  1 
ATOM   5407 C  C   . PHE C 1 108 ? -5.357  9.496   6.867   1    53.23  ? 278 PHE B C   1 
ATOM   5408 O  O   . PHE C 1 108 ? -6.198  10.308  6.497   1    57.53  ? 278 PHE B O   1 
ATOM   5409 C  CB  . PHE C 1 108 ? -6.155  7.039   7.031   1    45.5   ? 278 PHE B CB  1 
ATOM   5410 C  CG  . PHE C 1 108 ? -6.566  5.88    6.145   1    44.38  ? 278 PHE B CG  1 
ATOM   5411 C  CD1 . PHE C 1 108 ? -7.613  6.019   5.234   1    43.57  ? 278 PHE B CD1 1 
ATOM   5412 C  CD2 . PHE C 1 108 ? -5.883  4.664   6.192   1    42.75  ? 278 PHE B CD2 1 
ATOM   5413 C  CE1 . PHE C 1 108 ? -7.965  4.955   4.405   1    42.24  ? 278 PHE B CE1 1 
ATOM   5414 C  CE2 . PHE C 1 108 ? -6.26   3.603   5.373   1    39.35  ? 278 PHE B CE2 1 
ATOM   5415 C  CZ  . PHE C 1 108 ? -7.293  3.743   4.487   1    38.81  ? 278 PHE B CZ  1 
ATOM   5416 N  N   . VAL C 1 109 ? -4.402  9.787   7.767   1    50.55  ? 279 VAL B N   1 
ATOM   5417 C  CA  . VAL C 1 109 ? -4.284  11.114  8.354   1    49.78  ? 279 VAL B CA  1 
ATOM   5418 C  C   . VAL C 1 109 ? -3.835  12.099  7.285   1    51.54  ? 279 VAL B C   1 
ATOM   5419 O  O   . VAL C 1 109 ? -4.272  13.25   7.302   1    53.74  ? 279 VAL B O   1 
ATOM   5420 C  CB  . VAL C 1 109 ? -3.308  11.158  9.548   1    49.33  ? 279 VAL B CB  1 
ATOM   5421 C  CG1 . VAL C 1 109 ? -3.018  12.579  10.015  1    47.77  ? 279 VAL B CG1 1 
ATOM   5422 C  CG2 . VAL C 1 109 ? -3.773  10.291  10.708  1    46.98  ? 279 VAL B CG2 1 
ATOM   5423 N  N   . TYR C 1 110 ? -2.925  11.646  6.411   1    52.96  ? 280 TYR B N   1 
ATOM   5424 C  CA  . TYR C 1 110 ? -2.369  12.474  5.353   1    59.88  ? 280 TYR B CA  1 
ATOM   5425 C  C   . TYR C 1 110 ? -3.478  12.981  4.414   1    63.32  ? 280 TYR B C   1 
ATOM   5426 O  O   . TYR C 1 110 ? -3.553  14.181  4.154   1    68.94  ? 280 TYR B O   1 
ATOM   5427 C  CB  . TYR C 1 110 ? -1.097  11.888  4.719   1    64.06  ? 280 TYR B CB  1 
ATOM   5428 C  CG  . TYR C 1 110 ? -0.586  12.711  3.537   1    71.74  ? 280 TYR B CG  1 
ATOM   5429 C  CD1 . TYR C 1 110 ? 0.006   13.964  3.727   1    76.32  ? 280 TYR B CD1 1 
ATOM   5430 C  CD2 . TYR C 1 110 ? -0.764  12.275  2.223   1    72.14  ? 280 TYR B CD2 1 
ATOM   5431 C  CE1 . TYR C 1 110 ? 0.398   14.75   2.652   1    76.98  ? 280 TYR B CE1 1 
ATOM   5432 C  CE2 . TYR C 1 110 ? -0.364  13.043  1.143   1    77.15  ? 280 TYR B CE2 1 
ATOM   5433 C  CZ  . TYR C 1 110 ? 0.227   14.28   1.357   1    79.58  ? 280 TYR B CZ  1 
ATOM   5434 O  OH  . TYR C 1 110 ? 0.629   15.025  0.279   1    80.6   ? 280 TYR B OH  1 
ATOM   5435 N  N   . ILE C 1 111 ? -4.36   12.097  3.922   1    65.26  ? 281 ILE B N   1 
ATOM   5436 C  CA  . ILE C 1 111 ? -5.352  12.496  2.921   1    67.18  ? 281 ILE B CA  1 
ATOM   5437 C  C   . ILE C 1 111 ? -6.517  13.303  3.501   1    62.95  ? 281 ILE B C   1 
ATOM   5438 O  O   . ILE C 1 111 ? -7.307  13.854  2.742   1    63.26  ? 281 ILE B O   1 
ATOM   5439 C  CB  . ILE C 1 111 ? -5.903  11.308  2.121   1    66.87  ? 281 ILE B CB  1 
ATOM   5440 C  CG1 . ILE C 1 111 ? -6.29   10.188  3.068   1    68.23  ? 281 ILE B CG1 1 
ATOM   5441 C  CG2 . ILE C 1 111 ? -4.926  10.875  1.029   1    64.02  ? 281 ILE B CG2 1 
ATOM   5442 C  CD1 . ILE C 1 111 ? -7.602  9.525   2.706   1    76.66  ? 281 ILE B CD1 1 
ATOM   5443 N  N   . THR C 1 112 ? -6.665  13.356  4.825   1    60.18  ? 282 THR B N   1 
ATOM   5444 C  CA  . THR C 1 112 ? -7.618  14.293  5.404   1    60.16  ? 282 THR B CA  1 
ATOM   5445 C  C   . THR C 1 112 ? -7.025  15.703  5.499   1    68.35  ? 282 THR B C   1 
ATOM   5446 O  O   . THR C 1 112 ? -7.555  16.51   6.26    1    71.8   ? 282 THR B O   1 
ATOM   5447 C  CB  . THR C 1 112 ? -8.035  13.817  6.794   1    60.23  ? 282 THR B CB  1 
ATOM   5448 O  OG1 . THR C 1 112 ? -6.873  13.794  7.626   1    62.87  ? 282 THR B OG1 1 
ATOM   5449 C  CG2 . THR C 1 112 ? -8.76   12.485  6.789   1    53.72  ? 282 THR B CG2 1 
ATOM   5450 N  N   . ASP C 1 113 ? -5.916  15.974  4.777   1    77.22  ? 283 ASP B N   1 
ATOM   5451 C  CA  . ASP C 1 113 ? -5.186  17.241  4.778   1    83.01  ? 283 ASP B CA  1 
ATOM   5452 C  C   . ASP C 1 113 ? -4.947  17.774  6.189   1    86.41  ? 283 ASP B C   1 
ATOM   5453 O  O   . ASP C 1 113 ? -5.127  18.962  6.445   1    82.91  ? 283 ASP B O   1 
ATOM   5454 C  CB  . ASP C 1 113 ? -5.878  18.285  3.919   1    91.57  ? 283 ASP B CB  1 
ATOM   5455 C  CG  . ASP C 1 113 ? -5.481  18.26   2.454   1    103.58 ? 283 ASP B CG  1 
ATOM   5456 O  OD1 . ASP C 1 113 ? -4.42   18.844  2.134   1    104.14 ? 283 ASP B OD1 1 
ATOM   5457 O  OD2 . ASP C 1 113 ? -6.228  17.643  1.663   1    102.77 ? 283 ASP B OD2 1 
ATOM   5458 N  N   . ASP C 1 114 ? -4.566  16.883  7.112   1    97.76  ? 284 ASP B N   1 
ATOM   5459 C  CA  . ASP C 1 114 ? -4.304  17.238  8.502   1    98.41  ? 284 ASP B CA  1 
ATOM   5460 C  C   . ASP C 1 114 ? -5.458  18.02   9.144   1    84.78  ? 284 ASP B C   1 
ATOM   5461 O  O   . ASP C 1 114 ? -5.234  18.764  10.097  1    74.5   ? 284 ASP B O   1 
ATOM   5462 C  CB  . ASP C 1 114 ? -2.917  17.845  8.658   1    105.46 ? 284 ASP B CB  1 
ATOM   5463 C  CG  . ASP C 1 114 ? -1.783  17.016  8.066   1    106.14 ? 284 ASP B CG  1 
ATOM   5464 O  OD1 . ASP C 1 114 ? -1.646  15.829  8.444   1    99.75  ? 284 ASP B OD1 1 
ATOM   5465 O  OD2 . ASP C 1 114 ? -1.049  17.562  7.22    1    106.85 ? 284 ASP B OD2 1 
ATOM   5466 N  N   . THR C 1 115 ? -6.696  17.809  8.664   1    78.18  ? 285 THR B N   1 
ATOM   5467 C  CA  . THR C 1 115 ? -7.876  18.206  9.422   1    75.49  ? 285 THR B CA  1 
ATOM   5468 C  C   . THR C 1 115 ? -7.818  17.54   10.804  1    69.07  ? 285 THR B C   1 
ATOM   5469 O  O   . THR C 1 115 ? -7.856  18.215  11.826  1    74.47  ? 285 THR B O   1 
ATOM   5470 C  CB  . THR C 1 115 ? -9.176  17.889  8.668   1    74.31  ? 285 THR B CB  1 
ATOM   5471 O  OG1 . THR C 1 115 ? -9.08   18.229  7.292   1    68.49  ? 285 THR B OG1 1 
ATOM   5472 C  CG2 . THR C 1 115 ? -10.368 18.674  9.191   1    76.05  ? 285 THR B CG2 1 
ATOM   5473 N  N   . TYR C 1 116 ? -7.649  16.212  10.826  1    59.9   ? 286 TYR B N   1 
ATOM   5474 C  CA  . TYR C 1 116 ? -7.69   15.419  12.047  1    54.8   ? 286 TYR B CA  1 
ATOM   5475 C  C   . TYR C 1 116 ? -6.307  14.889  12.395  1    54.79  ? 286 TYR B C   1 
ATOM   5476 O  O   . TYR C 1 116 ? -5.444  14.816  11.529  1    59.62  ? 286 TYR B O   1 
ATOM   5477 C  CB  . TYR C 1 116 ? -8.577  14.199  11.802  1    49.68  ? 286 TYR B CB  1 
ATOM   5478 C  CG  . TYR C 1 116 ? -9.933  14.629  11.26   1    52     ? 286 TYR B CG  1 
ATOM   5479 C  CD1 . TYR C 1 116 ? -10.774 15.432  12.03   1    49.84  ? 286 TYR B CD1 1 
ATOM   5480 C  CD2 . TYR C 1 116 ? -10.336 14.291  9.966   1    47.12  ? 286 TYR B CD2 1 
ATOM   5481 C  CE1 . TYR C 1 116 ? -11.996 15.852  11.54   1    48.69  ? 286 TYR B CE1 1 
ATOM   5482 C  CE2 . TYR C 1 116 ? -11.556 14.719  9.47    1    48.74  ? 286 TYR B CE2 1 
ATOM   5483 C  CZ  . TYR C 1 116 ? -12.386 15.492  10.265  1    49.74  ? 286 TYR B CZ  1 
ATOM   5484 O  OH  . TYR C 1 116 ? -13.61  15.877  9.815   1    53.47  ? 286 TYR B OH  1 
ATOM   5485 N  N   . THR C 1 117 ? -6.122  14.524  13.673  1    52.84  ? 287 THR B N   1 
ATOM   5486 C  CA  . THR C 1 117 ? -4.916  13.872  14.182  1    53.71  ? 287 THR B CA  1 
ATOM   5487 C  C   . THR C 1 117 ? -5.034  12.34   14.13   1    52.62  ? 287 THR B C   1 
ATOM   5488 O  O   . THR C 1 117 ? -6.116  11.75   14.078  1    47.33  ? 287 THR B O   1 
ATOM   5489 C  CB  . THR C 1 117 ? -4.624  14.294  15.624  1    53.99  ? 287 THR B CB  1 
ATOM   5490 O  OG1 . THR C 1 117 ? -5.617  13.709  16.466  1    54.93  ? 287 THR B OG1 1 
ATOM   5491 C  CG2 . THR C 1 117 ? -4.575  15.795  15.83   1    53.19  ? 287 THR B CG2 1 
ATOM   5492 N  N   . LYS C 1 118 ? -3.879  11.683  14.249  1    54.57  ? 288 LYS B N   1 
ATOM   5493 C  CA  . LYS C 1 118 ? -3.794  10.235  14.266  1    53.03  ? 288 LYS B CA  1 
ATOM   5494 C  C   . LYS C 1 118 ? -4.623  9.697   15.428  1    51.14  ? 288 LYS B C   1 
ATOM   5495 O  O   . LYS C 1 118 ? -5.34   8.707   15.263  1    50.69  ? 288 LYS B O   1 
ATOM   5496 C  CB  . LYS C 1 118 ? -2.316  9.833   14.317  1    58.83  ? 288 LYS B CB  1 
ATOM   5497 C  CG  . LYS C 1 118 ? -2.008  8.34    14.226  1    66.27  ? 288 LYS B CG  1 
ATOM   5498 C  CD  . LYS C 1 118 ? -0.575  8.015   14.643  1    74.94  ? 288 LYS B CD  1 
ATOM   5499 C  CE  . LYS C 1 118 ? -0.348  6.565   14.974  1    80.88  ? 288 LYS B CE  1 
ATOM   5500 N  NZ  . LYS C 1 118 ? 0.95    6.337   15.619  1    87.73  ? 288 LYS B NZ  1 
ATOM   5501 N  N   . LYS C 1 119 ? -4.571  10.393  16.571  1    52.16  ? 289 LYS B N   1 
ATOM   5502 C  CA  . LYS C 1 119 ? -5.311  10.009  17.767  1    52.86  ? 289 LYS B CA  1 
ATOM   5503 C  C   . LYS C 1 119 ? -6.822  10.112  17.535  1    49.72  ? 289 LYS B C   1 
ATOM   5504 O  O   . LYS C 1 119 ? -7.57   9.244   17.97   1    49.58  ? 289 LYS B O   1 
ATOM   5505 C  CB  . LYS C 1 119 ? -4.8    10.813  18.965  1    60.48  ? 289 LYS B CB  1 
ATOM   5506 C  CG  . LYS C 1 119 ? -5.523  10.618  20.286  1    67.04  ? 289 LYS B CG  1 
ATOM   5507 C  CD  . LYS C 1 119 ? -4.685  11.048  21.491  1    78.54  ? 289 LYS B CD  1 
ATOM   5508 C  CE  . LYS C 1 119 ? -5.406  11.955  22.463  1    85.43  ? 289 LYS B CE  1 
ATOM   5509 N  NZ  . LYS C 1 119 ? -6.698  11.44   22.934  1    82.31  ? 289 LYS B NZ  1 
ATOM   5510 N  N   . GLN C 1 120 ? -7.273  11.136  16.801  1    47.21  ? 290 GLN B N   1 
ATOM   5511 C  CA  . GLN C 1 120 ? -8.682  11.227  16.45   1    48.91  ? 290 GLN B CA  1 
ATOM   5512 C  C   . GLN C 1 120 ? -9.117  10.124  15.468  1    48.87  ? 290 GLN B C   1 
ATOM   5513 O  O   . GLN C 1 120 ? -10.232 9.585   15.554  1    48.38  ? 290 GLN B O   1 
ATOM   5514 C  CB  . GLN C 1 120 ? -9.001  12.567  15.804  1    48.11  ? 290 GLN B CB  1 
ATOM   5515 C  CG  . GLN C 1 120 ? -8.899  13.767  16.731  1    53.03  ? 290 GLN B CG  1 
ATOM   5516 C  CD  . GLN C 1 120 ? -9.259  15.035  15.985  1    55.9   ? 290 GLN B CD  1 
ATOM   5517 O  OE1 . GLN C 1 120 ? -8.538  15.462  15.071  1    56.04  ? 290 GLN B OE1 1 
ATOM   5518 N  NE2 . GLN C 1 120 ? -10.414 15.603  16.316  1    51.17  ? 290 GLN B NE2 1 
ATOM   5519 N  N   . VAL C 1 121 ? -8.279  9.819   14.483  1    46.24  ? 291 VAL B N   1 
ATOM   5520 C  CA  . VAL C 1 121 ? -8.651  8.747   13.578  1    46.51  ? 291 VAL B CA  1 
ATOM   5521 C  C   . VAL C 1 121 ? -8.803  7.447   14.381  1    46.46  ? 291 VAL B C   1 
ATOM   5522 O  O   . VAL C 1 121 ? -9.79   6.743   14.234  1    42.47  ? 291 VAL B O   1 
ATOM   5523 C  CB  . VAL C 1 121 ? -7.661  8.596   12.405  1    46.07  ? 291 VAL B CB  1 
ATOM   5524 C  CG1 . VAL C 1 121 ? -8.027  7.422   11.504  1    46.99  ? 291 VAL B CG1 1 
ATOM   5525 C  CG2 . VAL C 1 121 ? -7.54   9.871   11.592  1    43.51  ? 291 VAL B CG2 1 
ATOM   5526 N  N   . LEU C 1 122 ? -7.844  7.143   15.262  1    47.79  ? 292 LEU B N   1 
ATOM   5527 C  CA  . LEU C 1 122 ? -7.853  5.858   15.948  1    50.89  ? 292 LEU B CA  1 
ATOM   5528 C  C   . LEU C 1 122 ? -9.048  5.768   16.894  1    52.22  ? 292 LEU B C   1 
ATOM   5529 O  O   . LEU C 1 122 ? -9.651  4.703   17.01   1    49.4   ? 292 LEU B O   1 
ATOM   5530 C  CB  . LEU C 1 122 ? -6.542  5.588   16.693  1    49.79  ? 292 LEU B CB  1 
ATOM   5531 C  CG  . LEU C 1 122 ? -5.291  5.414   15.824  1    49.01  ? 292 LEU B CG  1 
ATOM   5532 C  CD1 . LEU C 1 122 ? -4.076  5.099   16.68   1    48.35  ? 292 LEU B CD1 1 
ATOM   5533 C  CD2 . LEU C 1 122 ? -5.54   4.346   14.782  1    45.86  ? 292 LEU B CD2 1 
ATOM   5534 N  N   . ARG C 1 123 ? -9.362  6.883   17.577  1    53.11  ? 293 ARG B N   1 
ATOM   5535 C  CA  . ARG C 1 123 ? -10.455 6.926   18.535  1    50.62  ? 293 ARG B CA  1 
ATOM   5536 C  C   . ARG C 1 123 ? -11.792 6.755   17.813  1    45.67  ? 293 ARG B C   1 
ATOM   5537 O  O   . ARG C 1 123 ? -12.63  5.982   18.257  1    45.91  ? 293 ARG B O   1 
ATOM   5538 C  CB  . ARG C 1 123 ? -10.395 8.172   19.421  1    54.02  ? 293 ARG B CB  1 
ATOM   5539 C  CG  . ARG C 1 123 ? -9.418  8.115   20.583  1    58.28  ? 293 ARG B CG  1 
ATOM   5540 C  CD  . ARG C 1 123 ? -9.608  9.397   21.374  1    72.23  ? 293 ARG B CD  1 
ATOM   5541 N  NE  . ARG C 1 123 ? -9.515  9.196   22.822  1    83.45  ? 293 ARG B NE  1 
ATOM   5542 C  CZ  . ARG C 1 123 ? -10.279 8.348   23.498  1    90.17  ? 293 ARG B CZ  1 
ATOM   5543 N  NH1 . ARG C 1 123 ? -11.226 7.649   22.881  1    90.63  ? 293 ARG B NH1 1 
ATOM   5544 N  NH2 . ARG C 1 123 ? -10.088 8.207   24.8    1    87.99  ? 293 ARG B NH2 1 
ATOM   5545 N  N   . MET C 1 124 ? -11.989 7.468   16.702  1    42.83  ? 294 MET B N   1 
ATOM   5546 C  CA  . MET C 1 124 ? -13.161 7.274   15.855  1    44.37  ? 294 MET B CA  1 
ATOM   5547 C  C   . MET C 1 124 ? -13.268 5.821   15.389  1    41.96  ? 294 MET B C   1 
ATOM   5548 O  O   . MET C 1 124 ? -14.383 5.309   15.24   1    41.01  ? 294 MET B O   1 
ATOM   5549 C  CB  . MET C 1 124 ? -13.134 8.174   14.612  1    45.48  ? 294 MET B CB  1 
ATOM   5550 C  CG  . MET C 1 124 ? -14.383 8.057   13.744  1    43.07  ? 294 MET B CG  1 
ATOM   5551 S  SD  . MET C 1 124 ? -15.921 8.41    14.623  1    45.26  ? 294 MET B SD  1 
ATOM   5552 C  CE  . MET C 1 124 ? -15.95  10.208  14.717  1    38.79  ? 294 MET B CE  1 
ATOM   5553 N  N   . GLU C 1 125 ? -12.112 5.179   15.142  1    42.2   ? 295 GLU B N   1 
ATOM   5554 C  CA  . GLU C 1 125 ? -12.053 3.793   14.697  1    41.03  ? 295 GLU B CA  1 
ATOM   5555 C  C   . GLU C 1 125 ? -12.7   2.899   15.756  1    43.95  ? 295 GLU B C   1 
ATOM   5556 O  O   . GLU C 1 125 ? -13.588 2.087   15.441  1    42.97  ? 295 GLU B O   1 
ATOM   5557 C  CB  . GLU C 1 125 ? -10.617 3.348   14.406  1    40.2   ? 295 GLU B CB  1 
ATOM   5558 C  CG  . GLU C 1 125 ? -10.542 1.857   14.078  1    39.93  ? 295 GLU B CG  1 
ATOM   5559 C  CD  . GLU C 1 125 ? -9.165  1.242   13.922  1    43.59  ? 295 GLU B CD  1 
ATOM   5560 O  OE1 . GLU C 1 125 ? -8.434  1.057   14.933  1    44.88  ? 295 GLU B OE1 1 
ATOM   5561 O  OE2 . GLU C 1 125 ? -8.834  0.926   12.749  1    46.49  ? 295 GLU B OE2 1 
ATOM   5562 N  N   . HIS C 1 126 ? -12.228 3.076   17.001  1    41.92  ? 296 HIS B N   1 
ATOM   5563 C  CA  . HIS C 1 126 ? -12.784 2.428   18.173  1    45.6   ? 296 HIS B CA  1 
ATOM   5564 C  C   . HIS C 1 126 ? -14.306 2.6     18.227  1    44.92  ? 296 HIS B C   1 
ATOM   5565 O  O   . HIS C 1 126 ? -15.017 1.614   18.428  1    48.14  ? 296 HIS B O   1 
ATOM   5566 C  CB  . HIS C 1 126 ? -12.051 2.85    19.454  1    55.77  ? 296 HIS B CB  1 
ATOM   5567 C  CG  . HIS C 1 126 ? -11.957 1.693   20.383  1    77.62  ? 296 HIS B CG  1 
ATOM   5568 N  ND1 . HIS C 1 126 ? -12.75  1.502   21.497  1    86.44  ? 296 HIS B ND1 1 
ATOM   5569 C  CD2 . HIS C 1 126 ? -11.174 0.601   20.281  1    83.88  ? 296 HIS B CD2 1 
ATOM   5570 C  CE1 . HIS C 1 126 ? -12.441 0.333   22.044  1    98.59  ? 296 HIS B CE1 1 
ATOM   5571 N  NE2 . HIS C 1 126 ? -11.498 -0.24   21.315  1    94.79  ? 296 HIS B NE2 1 
ATOM   5572 N  N   . LEU C 1 127 ? -14.787 3.841   18.048  1    40.47  ? 297 LEU B N   1 
ATOM   5573 C  CA  . LEU C 1 127 ? -16.185 4.181   18.239  1    38.43  ? 297 LEU B CA  1 
ATOM   5574 C  C   . LEU C 1 127 ? -17.02  3.532   17.148  1    38.84  ? 297 LEU B C   1 
ATOM   5575 O  O   . LEU C 1 127 ? -18.065 2.952   17.436  1    36.92  ? 297 LEU B O   1 
ATOM   5576 C  CB  . LEU C 1 127 ? -16.401 5.694   18.297  1    39.07  ? 297 LEU B CB  1 
ATOM   5577 C  CG  . LEU C 1 127 ? -17.849 6.185   18.504  1    36.04  ? 297 LEU B CG  1 
ATOM   5578 C  CD1 . LEU C 1 127 ? -18.43  5.789   19.853  1    32.22  ? 297 LEU B CD1 1 
ATOM   5579 C  CD2 . LEU C 1 127 ? -17.948 7.7     18.341  1    34.94  ? 297 LEU B CD2 1 
ATOM   5580 N  N   . VAL C 1 128 ? -16.544 3.607   15.896  1    40.18  ? 298 VAL B N   1 
ATOM   5581 C  CA  . VAL C 1 128 ? -17.239 2.874   14.849  1    40.83  ? 298 VAL B CA  1 
ATOM   5582 C  C   . VAL C 1 128 ? -17.342 1.385   15.207  1    43.31  ? 298 VAL B C   1 
ATOM   5583 O  O   . VAL C 1 128 ? -18.401 0.772   15.059  1    50.25  ? 298 VAL B O   1 
ATOM   5584 C  CB  . VAL C 1 128 ? -16.637 3.091   13.458  1    41.59  ? 298 VAL B CB  1 
ATOM   5585 C  CG1 . VAL C 1 128 ? -17.285 2.172   12.433  1    40.79  ? 298 VAL B CG1 1 
ATOM   5586 C  CG2 . VAL C 1 128 ? -16.767 4.538   13.025  1    43.11  ? 298 VAL B CG2 1 
ATOM   5587 N  N   . LEU C 1 129 ? -16.259 0.782   15.695  1    40.83  ? 299 LEU B N   1 
ATOM   5588 C  CA  . LEU C 1 129 ? -16.344 -0.623  16.039  1    39.44  ? 299 LEU B CA  1 
ATOM   5589 C  C   . LEU C 1 129 ? -17.387 -0.827  17.125  1    39.52  ? 299 LEU B C   1 
ATOM   5590 O  O   . LEU C 1 129 ? -18.126 -1.802  17.08   1    41.22  ? 299 LEU B O   1 
ATOM   5591 C  CB  . LEU C 1 129 ? -14.989 -1.17   16.481  1    41.24  ? 299 LEU B CB  1 
ATOM   5592 C  CG  . LEU C 1 129 ? -13.924 -1.294  15.389  1    39.12  ? 299 LEU B CG  1 
ATOM   5593 C  CD1 . LEU C 1 129 ? -12.616 -1.73   16.026  1    37.2   ? 299 LEU B CD1 1 
ATOM   5594 C  CD2 . LEU C 1 129 ? -14.391 -2.283  14.338  1    35.79  ? 299 LEU B CD2 1 
ATOM   5595 N  N   . LYS C 1 130 ? -17.428 0.092   18.095  1    42.04  ? 300 LYS B N   1 
ATOM   5596 C  CA  . LYS C 1 130 ? -18.363 0.002   19.21   1    47.24  ? 300 LYS B CA  1 
ATOM   5597 C  C   . LYS C 1 130 ? -19.787 0.023   18.651  1    47.3   ? 300 LYS B C   1 
ATOM   5598 O  O   . LYS C 1 130 ? -20.58  -0.852  18.968  1    47.07  ? 300 LYS B O   1 
ATOM   5599 C  CB  . LYS C 1 130 ? -18.131 1.105   20.258  1    52.69  ? 300 LYS B CB  1 
ATOM   5600 C  CG  . LYS C 1 130 ? -19.082 1.068   21.468  1    65.45  ? 300 LYS B CG  1 
ATOM   5601 C  CD  . LYS C 1 130 ? -19.419 2.318   22.292  1    63.5   ? 300 LYS B CD  1 
ATOM   5602 C  CE  . LYS C 1 130 ? -20.893 2.398   22.659  1    62.92  ? 300 LYS B CE  1 
ATOM   5603 N  NZ  . LYS C 1 130 ? -21.145 3.291   23.799  1    64     ? 300 LYS B NZ  1 
ATOM   5604 N  N   . VAL C 1 131 ? -20.082 1.003   17.787  1    45.2   ? 301 VAL B N   1 
ATOM   5605 C  CA  . VAL C 1 131 ? -21.43  1.247   17.318  1    44.81  ? 301 VAL B CA  1 
ATOM   5606 C  C   . VAL C 1 131 ? -21.887 0.122   16.386  1    47.26  ? 301 VAL B C   1 
ATOM   5607 O  O   . VAL C 1 131 ? -23.067 -0.216  16.376  1    50.4   ? 301 VAL B O   1 
ATOM   5608 C  CB  . VAL C 1 131 ? -21.484 2.639   16.655  1    46.06  ? 301 VAL B CB  1 
ATOM   5609 C  CG1 . VAL C 1 131 ? -22.754 2.854   15.821  1    41.98  ? 301 VAL B CG1 1 
ATOM   5610 C  CG2 . VAL C 1 131 ? -21.292 3.75    17.689  1    40.34  ? 301 VAL B CG2 1 
ATOM   5611 N  N   . LEU C 1 132 ? -20.97  -0.466  15.607  1    44.29  ? 302 LEU B N   1 
ATOM   5612 C  CA  . LEU C 1 132 ? -21.348 -1.55   14.71   1    41.33  ? 302 LEU B CA  1 
ATOM   5613 C  C   . LEU C 1 132 ? -21.267 -2.919  15.39   1    41.64  ? 302 LEU B C   1 
ATOM   5614 O  O   . LEU C 1 132 ? -21.641 -3.925  14.774  1    42.13  ? 302 LEU B O   1 
ATOM   5615 C  CB  . LEU C 1 132 ? -20.46  -1.54   13.473  1    38.89  ? 302 LEU B CB  1 
ATOM   5616 C  CG  . LEU C 1 132 ? -20.529 -0.272  12.629  1    38.35  ? 302 LEU B CG  1 
ATOM   5617 C  CD1 . LEU C 1 132 ? -19.77  -0.482  11.354  1    38.47  ? 302 LEU B CD1 1 
ATOM   5618 C  CD2 . LEU C 1 132 ? -21.961 0.098   12.339  1    38.88  ? 302 LEU B CD2 1 
ATOM   5619 N  N   . ALA C 1 133 ? -20.734 -2.95   16.624  1    37.17  ? 303 ALA B N   1 
ATOM   5620 C  CA  . ALA C 1 133 ? -20.477 -4.188  17.345  1    37.94  ? 303 ALA B CA  1 
ATOM   5621 C  C   . ALA C 1 133 ? -19.603 -5.149  16.537  1    38.28  ? 303 ALA B C   1 
ATOM   5622 O  O   . ALA C 1 133 ? -19.813 -6.358  16.624  1    38.42  ? 303 ALA B O   1 
ATOM   5623 C  CB  . ALA C 1 133 ? -21.773 -4.843  17.788  1    34.14  ? 303 ALA B CB  1 
ATOM   5624 N  N   . PHE C 1 134 ? -18.641 -4.619  15.783  1    37.06  ? 304 PHE B N   1 
ATOM   5625 C  CA  . PHE C 1 134 ? -17.696 -5.424  14.957  1    41.71  ? 304 PHE B CA  1 
ATOM   5626 C  C   . PHE C 1 134 ? -18.439 -6.21   13.879  1    41.92  ? 304 PHE B C   1 
ATOM   5627 O  O   . PHE C 1 134 ? -17.872 -7.173  13.37   1    42.19  ? 304 PHE B O   1 
ATOM   5628 C  CB  . PHE C 1 134 ? -16.786 -6.349  15.774  1    42.01  ? 304 PHE B CB  1 
ATOM   5629 C  CG  . PHE C 1 134 ? -15.733 -5.698  16.656  1    48.86  ? 304 PHE B CG  1 
ATOM   5630 C  CD1 . PHE C 1 134 ? -16.062 -5.195  17.908  1    51.08  ? 304 PHE B CD1 1 
ATOM   5631 C  CD2 . PHE C 1 134 ? -14.408 -5.632  16.248  1    51.24  ? 304 PHE B CD2 1 
ATOM   5632 C  CE1 . PHE C 1 134 ? -15.098 -4.618  18.713  1    49.75  ? 304 PHE B CE1 1 
ATOM   5633 C  CE2 . PHE C 1 134 ? -13.448 -5.058  17.061  1    50.13  ? 304 PHE B CE2 1 
ATOM   5634 C  CZ  . PHE C 1 134 ? -13.795 -4.553  18.29   1    51.96  ? 304 PHE B CZ  1 
ATOM   5635 N  N   . ASP C 1 135 ? -19.656 -5.808  13.53   1    44.36  ? 305 ASP B N   1 
ATOM   5636 C  CA  . ASP C 1 135 ? -20.359 -6.476  12.4    1    49.06  ? 305 ASP B CA  1 
ATOM   5637 C  C   . ASP C 1 135 ? -19.859 -5.836  11.107  1    41.9   ? 305 ASP B C   1 
ATOM   5638 O  O   . ASP C 1 135 ? -20.526 -4.924  10.611  1    42.73  ? 305 ASP B O   1 
ATOM   5639 C  CB  . ASP C 1 135 ? -21.86  -6.518  12.622  1    57.55  ? 305 ASP B CB  1 
ATOM   5640 C  CG  . ASP C 1 135 ? -22.298 -7.425  13.76   1    72.65  ? 305 ASP B CG  1 
ATOM   5641 O  OD1 . ASP C 1 135 ? -21.976 -8.625  13.703  1    64.7   ? 305 ASP B OD1 1 
ATOM   5642 O  OD2 . ASP C 1 135 ? -22.943 -6.921  14.698  1    82.86  ? 305 ASP B OD2 1 
ATOM   5643 N  N   . LEU C 1 136 ? -18.744 -6.334  10.575  1    38.24  ? 306 LEU B N   1 
ATOM   5644 C  CA  . LEU C 1 136 ? -18.094 -5.69   9.413   1    38.08  ? 306 LEU B CA  1 
ATOM   5645 C  C   . LEU C 1 136 ? -18.193 -6.548  8.144   1    37.32  ? 306 LEU B C   1 
ATOM   5646 O  O   . LEU C 1 136 ? -17.992 -6.001  7.057   1    39.67  ? 306 LEU B O   1 
ATOM   5647 C  CB  . LEU C 1 136 ? -16.655 -5.475  9.876   1    40.07  ? 306 LEU B CB  1 
ATOM   5648 C  CG  . LEU C 1 136 ? -16.421 -4.429  10.969  1    40.61  ? 306 LEU B CG  1 
ATOM   5649 C  CD1 . LEU C 1 136 ? -14.992 -3.937  10.876  1    38.65  ? 306 LEU B CD1 1 
ATOM   5650 C  CD2 . LEU C 1 136 ? -17.379 -3.261  10.879  1    37.63  ? 306 LEU B CD2 1 
ATOM   5651 N  N   . ALA C 1 137 ? -18.481 -7.838  8.276   1    38.79  ? 307 ALA B N   1 
ATOM   5652 C  CA  . ALA C 1 137 ? -18.671 -8.704  7.112   1    38.32  ? 307 ALA B CA  1 
ATOM   5653 C  C   . ALA C 1 137 ? -20.052 -8.496  6.493   1    37.91  ? 307 ALA B C   1 
ATOM   5654 O  O   . ALA C 1 137 ? -20.898 -9.383  6.556   1    37     ? 307 ALA B O   1 
ATOM   5655 C  CB  . ALA C 1 137 ? -18.491 -10.17  7.485   1    34.98  ? 307 ALA B CB  1 
ATOM   5656 N  N   . ALA C 1 138 ? -20.272 -7.317  5.903   1    38.26  ? 308 ALA B N   1 
ATOM   5657 C  CA  . ALA C 1 138 ? -21.559 -6.943  5.34    1    40.85  ? 308 ALA B CA  1 
ATOM   5658 C  C   . ALA C 1 138 ? -21.586 -7.344  3.876   1    42.01  ? 308 ALA B C   1 
ATOM   5659 O  O   . ALA C 1 138 ? -20.586 -7.248  3.185   1    44.76  ? 308 ALA B O   1 
ATOM   5660 C  CB  . ALA C 1 138 ? -21.767 -5.441  5.432   1    37.72  ? 308 ALA B CB  1 
ATOM   5661 N  N   . PRO C 1 139 ? -22.756 -7.76   3.365   1    44.42  ? 309 PRO B N   1 
ATOM   5662 C  CA  . PRO C 1 139 ? -22.954 -7.929  1.926   1    39.76  ? 309 PRO B CA  1 
ATOM   5663 C  C   . PRO C 1 139 ? -22.975 -6.597  1.183   1    40.49  ? 309 PRO B C   1 
ATOM   5664 O  O   . PRO C 1 139 ? -23.614 -5.642  1.609   1    50.29  ? 309 PRO B O   1 
ATOM   5665 C  CB  . PRO C 1 139 ? -24.327 -8.613  1.867   1    39.28  ? 309 PRO B CB  1 
ATOM   5666 C  CG  . PRO C 1 139 ? -24.539 -9.169  3.257   1    43.96  ? 309 PRO B CG  1 
ATOM   5667 C  CD  . PRO C 1 139 ? -23.934 -8.121  4.169   1    42.53  ? 309 PRO B CD  1 
ATOM   5668 N  N   . THR C 1 140 ? -22.296 -6.559  0.039   1    40.7   ? 310 THR B N   1 
ATOM   5669 C  CA  . THR C 1 140 ? -22.229 -5.375  -0.808  1    38.73  ? 310 THR B CA  1 
ATOM   5670 C  C   . THR C 1 140 ? -22.908 -5.639  -2.153  1    38.87  ? 310 THR B C   1 
ATOM   5671 O  O   . THR C 1 140 ? -23.115 -6.785  -2.554  1    41.55  ? 310 THR B O   1 
ATOM   5672 C  CB  . THR C 1 140 ? -20.759 -4.985  -1.02   1    34.3   ? 310 THR B CB  1 
ATOM   5673 O  OG1 . THR C 1 140 ? -20.108 -6.066  -1.695  1    38.24  ? 310 THR B OG1 1 
ATOM   5674 C  CG2 . THR C 1 140 ? -20.05  -4.669  0.281   1    27.85  ? 310 THR B CG2 1 
ATOM   5675 N  N   . ILE C 1 141 ? -23.171 -4.549  -2.881  1    37.29  ? 311 ILE B N   1 
ATOM   5676 C  CA  . ILE C 1 141 ? -23.578 -4.613  -4.272  1    34.38  ? 311 ILE B CA  1 
ATOM   5677 C  C   . ILE C 1 141 ? -22.644 -5.545  -5.025  1    37.54  ? 311 ILE B C   1 
ATOM   5678 O  O   . ILE C 1 141 ? -23.134 -6.339  -5.826  1    40.66  ? 311 ILE B O   1 
ATOM   5679 C  CB  . ILE C 1 141 ? -23.627 -3.209  -4.89   1    34.13  ? 311 ILE B CB  1 
ATOM   5680 C  CG1 . ILE C 1 141 ? -24.77  -2.394  -4.303  1    34.44  ? 311 ILE B CG1 1 
ATOM   5681 C  CG2 . ILE C 1 141 ? -23.733 -3.275  -6.405  1    33.37  ? 311 ILE B CG2 1 
ATOM   5682 C  CD1 . ILE C 1 141 ? -24.762 -0.914  -4.658  1    34.47  ? 311 ILE B CD1 1 
ATOM   5683 N  N   . ASN C 1 142 ? -21.351 -5.475  -4.781  1    40.26  ? 312 ASN B N   1 
ATOM   5684 C  CA  . ASN C 1 142 ? -20.356 -6.244  -5.579  1    41.72  ? 312 ASN B CA  1 
ATOM   5685 C  C   . ASN C 1 142 ? -20.376 -7.747  -5.282  1    40.66  ? 312 ASN B C   1 
ATOM   5686 O  O   . ASN C 1 142 ? -20.124 -8.512  -6.216  1    41.97  ? 312 ASN B O   1 
ATOM   5687 C  CB  . ASN C 1 142 ? -18.958 -5.657  -5.425  1    46.39  ? 312 ASN B CB  1 
ATOM   5688 C  CG  . ASN C 1 142 ? -18.796 -4.362  -6.177  1    55.68  ? 312 ASN B CG  1 
ATOM   5689 O  OD1 . ASN C 1 142 ? -19.784 -3.782  -6.637  1    66.8   ? 312 ASN B OD1 1 
ATOM   5690 N  ND2 . ASN C 1 142 ? -17.564 -3.898  -6.313  1    55.21  ? 312 ASN B ND2 1 
ATOM   5691 N  N   . GLN C 1 143 ? -20.644 -8.153  -4.033  1    39.88  ? 313 GLN B N   1 
ATOM   5692 C  CA  . GLN C 1 143 ? -20.713 -9.582  -3.762  1    40.28  ? 313 GLN B CA  1 
ATOM   5693 C  C   . GLN C 1 143 ? -21.876 -10.222 -4.524  1    41.82  ? 313 GLN B C   1 
ATOM   5694 O  O   . GLN C 1 143 ? -21.824 -11.417 -4.81   1    49.86  ? 313 GLN B O   1 
ATOM   5695 C  CB  . GLN C 1 143 ? -20.886 -9.808  -2.265  1    37.82  ? 313 GLN B CB  1 
ATOM   5696 C  CG  . GLN C 1 143 ? -19.588 -9.638  -1.492  1    33.29  ? 313 GLN B CG  1 
ATOM   5697 C  CD  . GLN C 1 143 ? -19.801 -9.714  0       1    33.62  ? 313 GLN B CD  1 
ATOM   5698 O  OE1 . GLN C 1 143 ? -20.28  -10.718 0.536   1    39.61  ? 313 GLN B OE1 1 
ATOM   5699 N  NE2 . GLN C 1 143 ? -19.443 -8.651  0.698   1    33.01  ? 313 GLN B NE2 1 
ATOM   5700 N  N   . PHE C 1 144 ? -22.921 -9.43   -4.823  1    35.15  ? 314 PHE B N   1 
ATOM   5701 C  CA  . PHE C 1 144 ? -24.029 -9.901  -5.627  1    36     ? 314 PHE B CA  1 
ATOM   5702 C  C   . PHE C 1 144 ? -23.706 -9.826  -7.115  1    36.99  ? 314 PHE B C   1 
ATOM   5703 O  O   . PHE C 1 144 ? -24.03  -10.756 -7.86   1    41.6   ? 314 PHE B O   1 
ATOM   5704 C  CB  . PHE C 1 144 ? -25.281 -9.101  -5.291  1    32.8   ? 314 PHE B CB  1 
ATOM   5705 C  CG  . PHE C 1 144 ? -25.874 -9.505  -3.961  1    33.4   ? 314 PHE B CG  1 
ATOM   5706 C  CD1 . PHE C 1 144 ? -26.618 -10.688 -3.842  1    35.78  ? 314 PHE B CD1 1 
ATOM   5707 C  CD2 . PHE C 1 144 ? -25.717 -8.687  -2.843  1    35.18  ? 314 PHE B CD2 1 
ATOM   5708 C  CE1 . PHE C 1 144 ? -27.163 -11.054 -2.618  1    33.81  ? 314 PHE B CE1 1 
ATOM   5709 C  CE2 . PHE C 1 144 ? -26.273 -9.056  -1.617  1    35.2   ? 314 PHE B CE2 1 
ATOM   5710 C  CZ  . PHE C 1 144 ? -27.004 -10.225 -1.511  1    34.08  ? 314 PHE B CZ  1 
ATOM   5711 N  N   . LEU C 1 145 ? -23.101 -8.716  -7.551  1    35.03  ? 315 LEU B N   1 
ATOM   5712 C  CA  . LEU C 1 145 ? -22.784 -8.549  -8.962  1    39.07  ? 315 LEU B CA  1 
ATOM   5713 C  C   . LEU C 1 145 ? -21.945 -9.719  -9.481  1    42.89  ? 315 LEU B C   1 
ATOM   5714 O  O   . LEU C 1 145 ? -22.27  -10.303 -10.519 1    44.91  ? 315 LEU B O   1 
ATOM   5715 C  CB  . LEU C 1 145 ? -22.054 -7.232  -9.199  1    36.56  ? 315 LEU B CB  1 
ATOM   5716 C  CG  . LEU C 1 145 ? -22.95  -6.001  -9.288  1    36.31  ? 315 LEU B CG  1 
ATOM   5717 C  CD1 . LEU C 1 145 ? -22.073 -4.769  -9.416  1    36.67  ? 315 LEU B CD1 1 
ATOM   5718 C  CD2 . LEU C 1 145 ? -23.909 -6.129  -10.459 1    32.51  ? 315 LEU B CD2 1 
ATOM   5719 N  N   . THR C 1 146 ? -20.86  -10.038 -8.754  1    38.24  ? 316 THR B N   1 
ATOM   5720 C  CA  . THR C 1 146 ? -19.91  -11.032 -9.22   1    37.84  ? 316 THR B CA  1 
ATOM   5721 C  C   . THR C 1 146 ? -20.621 -12.375 -9.361  1    39.28  ? 316 THR B C   1 
ATOM   5722 O  O   . THR C 1 146 ? -20.303 -13.151 -10.265 1    47.37  ? 316 THR B O   1 
ATOM   5723 C  CB  . THR C 1 146 ? -18.629 -11.118 -8.379  1    36.86  ? 316 THR B CB  1 
ATOM   5724 O  OG1 . THR C 1 146 ? -19.055 -11.598 -7.111  1    39.04  ? 316 THR B OG1 1 
ATOM   5725 C  CG2 . THR C 1 146 ? -17.886 -9.801  -8.206  1    32.03  ? 316 THR B CG2 1 
ATOM   5726 N  N   . GLN C 1 147 ? -21.601 -12.648 -8.493  1    38.44  ? 317 GLN B N   1 
ATOM   5727 C  CA  . GLN C 1 147 ? -22.377 -13.876 -8.651  1    39.54  ? 317 GLN B CA  1 
ATOM   5728 C  C   . GLN C 1 147 ? -23.307 -13.831 -9.854  1    40.13  ? 317 GLN B C   1 
ATOM   5729 O  O   . GLN C 1 147 ? -23.458 -14.827 -10.556 1    42.82  ? 317 GLN B O   1 
ATOM   5730 C  CB  . GLN C 1 147 ? -23.237 -14.147 -7.437  1    36.62  ? 317 GLN B CB  1 
ATOM   5731 C  CG  . GLN C 1 147 ? -22.367 -14.575 -6.282  1    37.53  ? 317 GLN B CG  1 
ATOM   5732 C  CD  . GLN C 1 147 ? -23.193 -15.032 -5.125  1    38.33  ? 317 GLN B CD  1 
ATOM   5733 O  OE1 . GLN C 1 147 ? -24.086 -15.874 -5.279  1    41.28  ? 317 GLN B OE1 1 
ATOM   5734 N  NE2 . GLN C 1 147 ? -22.885 -14.444 -3.979  1    39.54  ? 317 GLN B NE2 1 
ATOM   5735 N  N   . TYR C 1 148 ? -23.944 -12.681 -10.06  1    39     ? 318 TYR B N   1 
ATOM   5736 C  CA  . TYR C 1 148 ? -24.843 -12.542 -11.188 1    40.86  ? 318 TYR B CA  1 
ATOM   5737 C  C   . TYR C 1 148 ? -24.049 -12.716 -12.483 1    43.35  ? 318 TYR B C   1 
ATOM   5738 O  O   . TYR C 1 148 ? -24.566 -13.25  -13.474 1    43.94  ? 318 TYR B O   1 
ATOM   5739 C  CB  . TYR C 1 148 ? -25.539 -11.181 -11.093 1    42.46  ? 318 TYR B CB  1 
ATOM   5740 C  CG  . TYR C 1 148 ? -26.46  -10.911 -9.907  1    39.15  ? 318 TYR B CG  1 
ATOM   5741 C  CD1 . TYR C 1 148 ? -26.8   -11.899 -8.998  1    38.61  ? 318 TYR B CD1 1 
ATOM   5742 C  CD2 . TYR C 1 148 ? -27.007 -9.649  -9.711  1    40.21  ? 318 TYR B CD2 1 
ATOM   5743 C  CE1 . TYR C 1 148 ? -27.649 -11.635 -7.935  1    41.09  ? 318 TYR B CE1 1 
ATOM   5744 C  CE2 . TYR C 1 148 ? -27.867 -9.376  -8.663  1    40.86  ? 318 TYR B CE2 1 
ATOM   5745 C  CZ  . TYR C 1 148 ? -28.201 -10.372 -7.759  1    44.07  ? 318 TYR B CZ  1 
ATOM   5746 O  OH  . TYR C 1 148 ? -29.05  -10.111 -6.692  1    39.62  ? 318 TYR B OH  1 
ATOM   5747 N  N   . PHE C 1 149 ? -22.777 -12.293 -12.464 1    41.57  ? 319 PHE B N   1 
ATOM   5748 C  CA  . PHE C 1 149 ? -21.927 -12.32  -13.65  1    42.03  ? 319 PHE B CA  1 
ATOM   5749 C  C   . PHE C 1 149 ? -21.758 -13.745 -14.185 1    41.09  ? 319 PHE B C   1 
ATOM   5750 O  O   . PHE C 1 149 ? -21.654 -13.936 -15.394 1    39.94  ? 319 PHE B O   1 
ATOM   5751 C  CB  . PHE C 1 149 ? -20.541 -11.721 -13.417 1    40.01  ? 319 PHE B CB  1 
ATOM   5752 C  CG  . PHE C 1 149 ? -20.51  -10.219 -13.23  1    39.61  ? 319 PHE B CG  1 
ATOM   5753 C  CD1 . PHE C 1 149 ? -21.623 -9.436  -13.529 1    41.04  ? 319 PHE B CD1 1 
ATOM   5754 C  CD2 . PHE C 1 149 ? -19.351 -9.597  -12.776 1    38.9   ? 319 PHE B CD2 1 
ATOM   5755 C  CE1 . PHE C 1 149 ? -21.584 -8.056  -13.348 1    40     ? 319 PHE B CE1 1 
ATOM   5756 C  CE2 . PHE C 1 149 ? -19.314 -8.215  -12.602 1    39.52  ? 319 PHE B CE2 1 
ATOM   5757 C  CZ  . PHE C 1 149 ? -20.428 -7.449  -12.89  1    39.79  ? 319 PHE B CZ  1 
ATOM   5758 N  N   . LEU C 1 150 ? -21.747 -14.738 -13.292 1    38.95  ? 320 LEU B N   1 
ATOM   5759 C  CA  . LEU C 1 150 ? -21.639 -16.133 -13.704 1    42.99  ? 320 LEU B CA  1 
ATOM   5760 C  C   . LEU C 1 150 ? -22.799 -16.577 -14.607 1    44.73  ? 320 LEU B C   1 
ATOM   5761 O  O   . LEU C 1 150 ? -22.712 -17.64  -15.22  1    44.21  ? 320 LEU B O   1 
ATOM   5762 C  CB  . LEU C 1 150 ? -21.467 -17.02  -12.47  1    38.7   ? 320 LEU B CB  1 
ATOM   5763 C  CG  . LEU C 1 150 ? -20.257 -16.651 -11.594 1    39.19  ? 320 LEU B CG  1 
ATOM   5764 C  CD1 . LEU C 1 150 ? -20.268 -17.348 -10.226 1    36.49  ? 320 LEU B CD1 1 
ATOM   5765 C  CD2 . LEU C 1 150 ? -18.869 -16.781 -12.289 1    34.56  ? 320 LEU B CD2 1 
ATOM   5766 N  N   . HIS C 1 151 ? -23.861 -15.762 -14.716 1    44.55  ? 321 HIS B N   1 
ATOM   5767 C  CA  . HIS C 1 151 ? -25.052 -16.157 -15.457 1    46.13  ? 321 HIS B CA  1 
ATOM   5768 C  C   . HIS C 1 151 ? -25.058 -15.626 -16.895 1    51.23  ? 321 HIS B C   1 
ATOM   5769 O  O   . HIS C 1 151 ? -25.981 -15.932 -17.644 1    63.63  ? 321 HIS B O   1 
ATOM   5770 C  CB  . HIS C 1 151 ? -26.34  -15.798 -14.697 1    43.85  ? 321 HIS B CB  1 
ATOM   5771 C  CG  . HIS C 1 151 ? -26.606 -16.667 -13.518 1    43.89  ? 321 HIS B CG  1 
ATOM   5772 N  ND1 . HIS C 1 151 ? -27.666 -17.547 -13.483 1    46.23  ? 321 HIS B ND1 1 
ATOM   5773 C  CD2 . HIS C 1 151 ? -25.961 -16.806 -12.338 1    40.92  ? 321 HIS B CD2 1 
ATOM   5774 C  CE1 . HIS C 1 151 ? -27.648 -18.205 -12.324 1    44.35  ? 321 HIS B CE1 1 
ATOM   5775 N  NE2 . HIS C 1 151 ? -26.613 -17.78  -11.622 1    42.13  ? 321 HIS B NE2 1 
ATOM   5776 N  N   . GLN C 1 152 ? -24.044 -14.857 -17.305 1    53.58  ? 322 GLN B N   1 
ATOM   5777 C  CA  . GLN C 1 152 ? -23.961 -14.368 -18.676 1    59.69  ? 322 GLN B CA  1 
ATOM   5778 C  C   . GLN C 1 152 ? -23.2   -15.41  -19.51  1    66.88  ? 322 GLN B C   1 
ATOM   5779 O  O   . GLN C 1 152 ? -22.144 -15.9   -19.105 1    62.77  ? 322 GLN B O   1 
ATOM   5780 C  CB  . GLN C 1 152 ? -23.365 -12.955 -18.687 1    57.41  ? 322 GLN B CB  1 
ATOM   5781 C  CG  . GLN C 1 152 ? -21.873 -12.98  -18.377 1    68.96  ? 322 GLN B CG  1 
ATOM   5782 C  CD  . GLN C 1 152 ? -21.223 -11.696 -17.903 1    73.08  ? 322 GLN B CD  1 
ATOM   5783 O  OE1 . GLN C 1 152 ? -20.398 -11.718 -16.979 1    63.54  ? 322 GLN B OE1 1 
ATOM   5784 N  NE2 . GLN C 1 152 ? -21.495 -10.594 -18.594 1    74.5   ? 322 GLN B NE2 1 
ATOM   5785 N  N   . GLN C 1 153 ? -23.76  -15.768 -20.676 1    81.56  ? 323 GLN B N   1 
ATOM   5786 C  CA  . GLN C 1 153 ? -23.168 -16.732 -21.602 1    98.58  ? 323 GLN B CA  1 
ATOM   5787 C  C   . GLN C 1 153 ? -23.05  -16.113 -23     1    98.56  ? 323 GLN B C   1 
ATOM   5788 O  O   . GLN C 1 153 ? -24.044 -16.015 -23.724 1    98.52  ? 323 GLN B O   1 
ATOM   5789 C  CB  . GLN C 1 153 ? -23.965 -18.039 -21.622 1    109.3  ? 323 GLN B CB  1 
ATOM   5790 C  CG  . GLN C 1 153 ? -25.474 -17.848 -21.781 1    111.72 ? 323 GLN B CG  1 
ATOM   5791 C  CD  . GLN C 1 153 ? -26.292 -19.035 -21.319 1    113.16 ? 323 GLN B CD  1 
ATOM   5792 O  OE1 . GLN C 1 153 ? -26.976 -19.674 -22.124 1    112.74 ? 323 GLN B OE1 1 
ATOM   5793 N  NE2 . GLN C 1 153 ? -26.232 -19.337 -20.026 1    99.18  ? 323 GLN B NE2 1 
ATOM   5794 N  N   . PRO C 1 154 ? -21.84  -15.65  -23.424 1    92.3   ? 324 PRO B N   1 
ATOM   5795 C  CA  . PRO C 1 154 ? -20.587 -15.806 -22.662 1    79.38  ? 324 PRO B CA  1 
ATOM   5796 C  C   . PRO C 1 154 ? -20.253 -14.573 -21.821 1    68.99  ? 324 PRO B C   1 
ATOM   5797 O  O   . PRO C 1 154 ? -20.921 -13.534 -21.939 1    62.74  ? 324 PRO B O   1 
ATOM   5798 C  CB  . PRO C 1 154 ? -19.58  -15.954 -23.816 1    78.28  ? 324 PRO B CB  1 
ATOM   5799 C  CG  . PRO C 1 154 ? -20.105 -14.987 -24.863 1    78.88  ? 324 PRO B CG  1 
ATOM   5800 C  CD  . PRO C 1 154 ? -21.626 -14.902 -24.677 1    84.2   ? 324 PRO B CD  1 
ATOM   5801 N  N   . ALA C 1 155 ? -19.194 -14.684 -21.002 1    61.43  ? 325 ALA B N   1 
ATOM   5802 C  CA  . ALA C 1 155 ? -18.747 -13.551 -20.196 1    56.46  ? 325 ALA B CA  1 
ATOM   5803 C  C   . ALA C 1 155 ? -18.473 -12.353 -21.111 1    58.13  ? 325 ALA B C   1 
ATOM   5804 O  O   . ALA C 1 155 ? -18.033 -12.523 -22.248 1    64.1   ? 325 ALA B O   1 
ATOM   5805 C  CB  . ALA C 1 155 ? -17.552 -13.929 -19.351 1    49.03  ? 325 ALA B CB  1 
ATOM   5806 N  N   . ASN C 1 156 ? -18.783 -11.146 -20.627 1    55.14  ? 326 ASN B N   1 
ATOM   5807 C  CA  . ASN C 1 156 ? -18.612 -9.922  -21.393 1    53.09  ? 326 ASN B CA  1 
ATOM   5808 C  C   . ASN C 1 156 ? -18.167 -8.805  -20.453 1    56.27  ? 326 ASN B C   1 
ATOM   5809 O  O   . ASN C 1 156 ? -18.955 -8.393  -19.597 1    58.04  ? 326 ASN B O   1 
ATOM   5810 C  CB  . ASN C 1 156 ? -19.912 -9.52   -22.076 1    48.88  ? 326 ASN B CB  1 
ATOM   5811 C  CG  . ASN C 1 156 ? -19.705 -8.399  -23.064 1    53.36  ? 326 ASN B CG  1 
ATOM   5812 O  OD1 . ASN C 1 156 ? -19.155 -7.346  -22.717 1    57.83  ? 326 ASN B OD1 1 
ATOM   5813 N  ND2 . ASN C 1 156 ? -20.101 -8.608  -24.311 1    54.46  ? 326 ASN B ND2 1 
ATOM   5814 N  N   . CYS C 1 157 ? -16.935 -8.304  -20.654 1    55.17  ? 327 CYS B N   1 
ATOM   5815 C  CA  . CYS C 1 157 ? -16.246 -7.43   -19.704 1    57.27  ? 327 CYS B CA  1 
ATOM   5816 C  C   . CYS C 1 157 ? -16.765 -5.994  -19.724 1    50.69  ? 327 CYS B C   1 
ATOM   5817 O  O   . CYS C 1 157 ? -16.694 -5.297  -18.716 1    45.06  ? 327 CYS B O   1 
ATOM   5818 C  CB  . CYS C 1 157 ? -14.764 -7.321  -20.042 1    70.08  ? 327 CYS B CB  1 
ATOM   5819 S  SG  . CYS C 1 157 ? -13.895 -8.878  -19.751 1    93.51  ? 327 CYS B SG  1 
ATOM   5820 N  N   . LYS C 1 158 ? -17.166 -5.547  -20.916 1    52.97  ? 328 LYS B N   1 
ATOM   5821 C  CA  . LYS C 1 158 ? -17.919 -4.321  -21.103 1    57.03  ? 328 LYS B CA  1 
ATOM   5822 C  C   . LYS C 1 158 ? -19.116 -4.363  -20.137 1    53.74  ? 328 LYS B C   1 
ATOM   5823 O  O   . LYS C 1 158 ? -19.281 -3.478  -19.302 1    48.44  ? 328 LYS B O   1 
ATOM   5824 C  CB  . LYS C 1 158 ? -18.21  -4.291  -22.61  1    61.52  ? 328 LYS B CB  1 
ATOM   5825 C  CG  . LYS C 1 158 ? -18.142 -2.982  -23.366 1    66.31  ? 328 LYS B CG  1 
ATOM   5826 C  CD  . LYS C 1 158 ? -16.792 -2.286  -23.31  1    76.4   ? 328 LYS B CD  1 
ATOM   5827 C  CE  . LYS C 1 158 ? -15.681 -2.948  -24.077 1    85.2   ? 328 LYS B CE  1 
ATOM   5828 N  NZ  . LYS C 1 158 ? -14.445 -2.15   -24.079 1    72.39  ? 328 LYS B NZ  1 
ATOM   5829 N  N   . VAL C 1 159 ? -19.893 -5.454  -20.17  1    52.17  ? 329 VAL B N   1 
ATOM   5830 C  CA  . VAL C 1 159 ? -21.056 -5.608  -19.302 1    48.25  ? 329 VAL B CA  1 
ATOM   5831 C  C   . VAL C 1 159 ? -20.628 -5.575  -17.832 1    46.61  ? 329 VAL B C   1 
ATOM   5832 O  O   . VAL C 1 159 ? -21.177 -4.812  -17.038 1    46.95  ? 329 VAL B O   1 
ATOM   5833 C  CB  . VAL C 1 159 ? -21.881 -6.879  -19.599 1    44.93  ? 329 VAL B CB  1 
ATOM   5834 C  CG1 . VAL C 1 159 ? -22.807 -7.189  -18.437 1    41.36  ? 329 VAL B CG1 1 
ATOM   5835 C  CG2 . VAL C 1 159 ? -22.644 -6.816  -20.922 1    43.56  ? 329 VAL B CG2 1 
ATOM   5836 N  N   . GLU C 1 160 ? -19.659 -6.419  -17.465 1    44.42  ? 330 GLU B N   1 
ATOM   5837 C  CA  . GLU C 1 160 ? -19.23  -6.504  -16.077 1    44.5   ? 330 GLU B CA  1 
ATOM   5838 C  C   . GLU C 1 160 ? -18.81  -5.132  -15.563 1    45.57  ? 330 GLU B C   1 
ATOM   5839 O  O   . GLU C 1 160 ? -19.317 -4.733  -14.525 1    46.56  ? 330 GLU B O   1 
ATOM   5840 C  CB  . GLU C 1 160 ? -18.126 -7.53   -15.865 1    43.47  ? 330 GLU B CB  1 
ATOM   5841 C  CG  . GLU C 1 160 ? -18.646 -8.955  -16.01  1    44.32  ? 330 GLU B CG  1 
ATOM   5842 C  CD  . GLU C 1 160 ? -17.611 -10.063 -16.007 1    45.53  ? 330 GLU B CD  1 
ATOM   5843 O  OE1 . GLU C 1 160 ? -16.661 -10.038 -15.198 1    48.05  ? 330 GLU B OE1 1 
ATOM   5844 O  OE2 . GLU C 1 160 ? -17.819 -10.995 -16.786 1    48.96  ? 330 GLU B OE2 1 
ATOM   5845 N  N   . SER C 1 161 ? -17.941 -4.416  -16.301 1    43.67  ? 331 SER B N   1 
ATOM   5846 C  CA  . SER C 1 161 ? -17.468 -3.119  -15.825 1    44     ? 331 SER B CA  1 
ATOM   5847 C  C   . SER C 1 161 ? -18.615 -2.105  -15.752 1    46.43  ? 331 SER B C   1 
ATOM   5848 O  O   . SER C 1 161 ? -18.66  -1.288  -14.835 1    45.55  ? 331 SER B O   1 
ATOM   5849 C  CB  . SER C 1 161 ? -16.273 -2.551  -16.598 1    42.71  ? 331 SER B CB  1 
ATOM   5850 O  OG  . SER C 1 161 ? -15.115 -3.355  -16.471 1    42.05  ? 331 SER B OG  1 
ATOM   5851 N  N   . LEU C 1 162 ? -19.547 -2.14   -16.715 1    46.49  ? 332 LEU B N   1 
ATOM   5852 C  CA  . LEU C 1 162 ? -20.612 -1.144  -16.732 1    45.66  ? 332 LEU B CA  1 
ATOM   5853 C  C   . LEU C 1 162 ? -21.511 -1.332  -15.51  1    45.92  ? 332 LEU B C   1 
ATOM   5854 O  O   . LEU C 1 162 ? -21.995 -0.347  -14.946 1    45.38  ? 332 LEU B O   1 
ATOM   5855 C  CB  . LEU C 1 162 ? -21.41  -1.197  -18.031 1    43.93  ? 332 LEU B CB  1 
ATOM   5856 C  CG  . LEU C 1 162 ? -22.581 -0.219  -18.135 1    45.05  ? 332 LEU B CG  1 
ATOM   5857 C  CD1 . LEU C 1 162 ? -22.089 1.21    -17.991 1    43.36  ? 332 LEU B CD1 1 
ATOM   5858 C  CD2 . LEU C 1 162 ? -23.329 -0.403  -19.438 1    43.45  ? 332 LEU B CD2 1 
ATOM   5859 N  N   . ALA C 1 163 ? -21.73  -2.598  -15.117 1    44.41  ? 333 ALA B N   1 
ATOM   5860 C  CA  . ALA C 1 163 ? -22.565 -2.894  -13.96  1    40.64  ? 333 ALA B CA  1 
ATOM   5861 C  C   . ALA C 1 163 ? -21.905 -2.39   -12.683 1    42.61  ? 333 ALA B C   1 
ATOM   5862 O  O   . ALA C 1 163 ? -22.629 -1.841  -11.86  1    41.99  ? 333 ALA B O   1 
ATOM   5863 C  CB  . ALA C 1 163 ? -22.9   -4.362  -13.858 1    34.78  ? 333 ALA B CB  1 
ATOM   5864 N  N   . MET C 1 164 ? -20.573 -2.596  -12.53  1    41.66  ? 334 MET B N   1 
ATOM   5865 C  CA  . MET C 1 164 ? -19.8   -2.08   -11.403 1    42.76  ? 334 MET B CA  1 
ATOM   5866 C  C   . MET C 1 164 ? -19.978 -0.564  -11.303 1    43.89  ? 334 MET B C   1 
ATOM   5867 O  O   . MET C 1 164 ? -20.244 -0.033  -10.216 1    45.03  ? 334 MET B O   1 
ATOM   5868 C  CB  . MET C 1 164 ? -18.291 -2.314  -11.552 1    48.75  ? 334 MET B CB  1 
ATOM   5869 C  CG  . MET C 1 164 ? -17.814 -3.754  -11.419 1    54.7   ? 334 MET B CG  1 
ATOM   5870 S  SD  . MET C 1 164 ? -18.303 -4.378  -9.802  1    63.28  ? 334 MET B SD  1 
ATOM   5871 C  CE  . MET C 1 164 ? -17.286 -5.861  -9.796  1    78.52  ? 334 MET B CE  1 
ATOM   5872 N  N   . PHE C 1 165 ? -19.808 0.112   -12.449 1    43.18  ? 335 PHE B N   1 
ATOM   5873 C  CA  . PHE C 1 165 ? -19.956 1.554   -12.54  1    47.04  ? 335 PHE B CA  1 
ATOM   5874 C  C   . PHE C 1 165 ? -21.321 2.02    -12.024 1    47.92  ? 335 PHE B C   1 
ATOM   5875 O  O   . PHE C 1 165 ? -21.412 2.946   -11.212 1    46.18  ? 335 PHE B O   1 
ATOM   5876 C  CB  . PHE C 1 165 ? -19.705 1.941   -13.993 1    46.91  ? 335 PHE B CB  1 
ATOM   5877 C  CG  . PHE C 1 165 ? -20.025 3.377   -14.371 1    48.36  ? 335 PHE B CG  1 
ATOM   5878 C  CD1 . PHE C 1 165 ? -19.312 4.435   -13.816 1    48.52  ? 335 PHE B CD1 1 
ATOM   5879 C  CD2 . PHE C 1 165 ? -21.002 3.654   -15.321 1    49.39  ? 335 PHE B CD2 1 
ATOM   5880 C  CE1 . PHE C 1 165 ? -19.563 5.742   -14.207 1    49.46  ? 335 PHE B CE1 1 
ATOM   5881 C  CE2 . PHE C 1 165 ? -21.271 4.959   -15.703 1    48.97  ? 335 PHE B CE2 1 
ATOM   5882 C  CZ  . PHE C 1 165 ? -20.545 5.999   -15.149 1    54.09  ? 335 PHE B CZ  1 
ATOM   5883 N  N   . LEU C 1 166 ? -22.387 1.368   -12.494 1    48.3   ? 336 LEU B N   1 
ATOM   5884 C  CA  . LEU C 1 166 ? -23.742 1.749   -12.127 1    45.56  ? 336 LEU B CA  1 
ATOM   5885 C  C   . LEU C 1 166 ? -23.949 1.514   -10.637 1    45.88  ? 336 LEU B C   1 
ATOM   5886 O  O   . LEU C 1 166 ? -24.558 2.332   -9.945  1    51.42  ? 336 LEU B O   1 
ATOM   5887 C  CB  . LEU C 1 166 ? -24.728 0.961   -12.986 1    43.05  ? 336 LEU B CB  1 
ATOM   5888 C  CG  . LEU C 1 166 ? -24.776 1.354   -14.469 1    40.94  ? 336 LEU B CG  1 
ATOM   5889 C  CD1 . LEU C 1 166 ? -25.731 0.469   -15.256 1    40.25  ? 336 LEU B CD1 1 
ATOM   5890 C  CD2 . LEU C 1 166 ? -25.143 2.814   -14.64  1    40.13  ? 336 LEU B CD2 1 
ATOM   5891 N  N   . GLY C 1 167 ? -23.416 0.393   -10.155 1    43.68  ? 337 GLY B N   1 
ATOM   5892 C  CA  . GLY C 1 167 ? -23.434 0.07    -8.743  1    39.08  ? 337 GLY B CA  1 
ATOM   5893 C  C   . GLY C 1 167 ? -22.783 1.173   -7.917  1    42.49  ? 337 GLY B C   1 
ATOM   5894 O  O   . GLY C 1 167 ? -23.397 1.619   -6.953  1    48.19  ? 337 GLY B O   1 
ATOM   5895 N  N   . GLU C 1 168 ? -21.579 1.621   -8.314  1    39.83  ? 338 GLU B N   1 
ATOM   5896 C  CA  . GLU C 1 168 ? -20.889 2.68    -7.592  1    42.02  ? 338 GLU B CA  1 
ATOM   5897 C  C   . GLU C 1 168 ? -21.683 3.99    -7.648  1    43.45  ? 338 GLU B C   1 
ATOM   5898 O  O   . GLU C 1 168 ? -21.788 4.672   -6.632  1    45.51  ? 338 GLU B O   1 
ATOM   5899 C  CB  . GLU C 1 168 ? -19.461 2.957   -8.062  1    40.01  ? 338 GLU B CB  1 
ATOM   5900 C  CG  . GLU C 1 168 ? -18.524 1.775   -7.864  1    42.16  ? 338 GLU B CG  1 
ATOM   5901 C  CD  . GLU C 1 168 ? -17.04  2.102   -7.966  1    45.38  ? 338 GLU B CD  1 
ATOM   5902 O  OE1 . GLU C 1 168 ? -16.619 3.292   -7.882  1    43.58  ? 338 GLU B OE1 1 
ATOM   5903 O  OE2 . GLU C 1 168 ? -16.293 1.111   -8.147  1    43.34  ? 338 GLU B OE2 1 
ATOM   5904 N  N   . LEU C 1 169 ? -22.216 4.372   -8.816  1    40.44  ? 339 LEU B N   1 
ATOM   5905 C  CA  . LEU C 1 169 ? -23.002 5.603   -8.869  1    43.32  ? 339 LEU B CA  1 
ATOM   5906 C  C   . LEU C 1 169 ? -24.037 5.661   -7.736  1    42.52  ? 339 LEU B C   1 
ATOM   5907 O  O   . LEU C 1 169 ? -24.192 6.698   -7.094  1    45.16  ? 339 LEU B O   1 
ATOM   5908 C  CB  . LEU C 1 169 ? -23.642 5.805   -10.241 1    39.56  ? 339 LEU B CB  1 
ATOM   5909 C  CG  . LEU C 1 169 ? -22.683 6.186   -11.374 1    41.09  ? 339 LEU B CG  1 
ATOM   5910 C  CD1 . LEU C 1 169 ? -23.469 6.372   -12.65  1    41.22  ? 339 LEU B CD1 1 
ATOM   5911 C  CD2 . LEU C 1 169 ? -21.831 7.426   -11.098 1    39.68  ? 339 LEU B CD2 1 
ATOM   5912 N  N   . SER C 1 170 ? -24.699 4.531   -7.475  1    38.28  ? 340 SER B N   1 
ATOM   5913 C  CA  . SER C 1 170 ? -25.746 4.391   -6.472  1    43.99  ? 340 SER B CA  1 
ATOM   5914 C  C   . SER C 1 170 ? -25.275 4.738   -5.048  1    44.56  ? 340 SER B C   1 
ATOM   5915 O  O   . SER C 1 170 ? -26.07  5.216   -4.224  1    43.88  ? 340 SER B O   1 
ATOM   5916 C  CB  . SER C 1 170 ? -26.346 2.98    -6.527  1    45.3   ? 340 SER B CB  1 
ATOM   5917 O  OG  . SER C 1 170 ? -25.726 2.13    -5.569  1    46.29  ? 340 SER B OG  1 
ATOM   5918 N  N   . LEU C 1 171 ? -24.002 4.45    -4.737  1    39.71  ? 341 LEU B N   1 
ATOM   5919 C  CA  . LEU C 1 171 ? -23.427 4.798   -3.45   1    38.1   ? 341 LEU B CA  1 
ATOM   5920 C  C   . LEU C 1 171 ? -23.544 6.297   -3.152  1    40.65  ? 341 LEU B C   1 
ATOM   5921 O  O   . LEU C 1 171 ? -23.56  6.687   -1.983  1    41.64  ? 341 LEU B O   1 
ATOM   5922 C  CB  . LEU C 1 171 ? -21.951 4.404   -3.429  1    37.7   ? 341 LEU B CB  1 
ATOM   5923 C  CG  . LEU C 1 171 ? -21.599 2.916   -3.546  1    35.65  ? 341 LEU B CG  1 
ATOM   5924 C  CD1 . LEU C 1 171 ? -20.075 2.857   -3.605  1    31.33  ? 341 LEU B CD1 1 
ATOM   5925 C  CD2 . LEU C 1 171 ? -22.157 2.041   -2.433  1    28.9   ? 341 LEU B CD2 1 
ATOM   5926 N  N   . ILE C 1 172 ? -23.555 7.142   -4.195  1    41.25  ? 342 ILE B N   1 
ATOM   5927 C  CA  . ILE C 1 172 ? -23.391 8.579   -3.999  1    42.1   ? 342 ILE B CA  1 
ATOM   5928 C  C   . ILE C 1 172 ? -24.658 9.193   -3.406  1    45.18  ? 342 ILE B C   1 
ATOM   5929 O  O   . ILE C 1 172 ? -24.57  10.054  -2.53   1    49.26  ? 342 ILE B O   1 
ATOM   5930 C  CB  . ILE C 1 172 ? -22.96  9.298   -5.289  1    40.13  ? 342 ILE B CB  1 
ATOM   5931 C  CG1 . ILE C 1 172 ? -21.646 8.756   -5.854  1    39.88  ? 342 ILE B CG1 1 
ATOM   5932 C  CG2 . ILE C 1 172 ? -22.869 10.8    -5.078  1    38.76  ? 342 ILE B CG2 1 
ATOM   5933 C  CD1 . ILE C 1 172 ? -20.419 9.18    -5.076  1    40.74  ? 342 ILE B CD1 1 
ATOM   5934 N  N   . ASP C 1 173 ? -25.82  8.719   -3.87   1    45.24  ? 343 ASP B N   1 
ATOM   5935 C  CA  . ASP C 1 173 ? -27.103 9.356   -3.626  1    45.16  ? 343 ASP B CA  1 
ATOM   5936 C  C   . ASP C 1 173 ? -27.939 8.505   -2.694  1    50.45  ? 343 ASP B C   1 
ATOM   5937 O  O   . ASP C 1 173 ? -28.587 7.556   -3.145  1    56.96  ? 343 ASP B O   1 
ATOM   5938 C  CB  . ASP C 1 173 ? -27.837 9.596   -4.926  1    44.97  ? 343 ASP B CB  1 
ATOM   5939 C  CG  . ASP C 1 173 ? -26.992 10.431  -5.869  1    49.66  ? 343 ASP B CG  1 
ATOM   5940 O  OD1 . ASP C 1 173 ? -26.523 11.473  -5.372  1    55.31  ? 343 ASP B OD1 1 
ATOM   5941 O  OD2 . ASP C 1 173 ? -26.78  10.026  -7.048  1    48.92  ? 343 ASP B OD2 1 
ATOM   5942 N  N   . ALA C 1 174 ? -27.923 8.895   -1.412  1    47.46  ? 344 ALA B N   1 
ATOM   5943 C  CA  . ALA C 1 174 ? -28.698 8.237   -0.38   1    47.61  ? 344 ALA B CA  1 
ATOM   5944 C  C   . ALA C 1 174 ? -30.181 8.381   -0.692  1    48.13  ? 344 ALA B C   1 
ATOM   5945 O  O   . ALA C 1 174 ? -30.963 7.504   -0.365  1    53.05  ? 344 ALA B O   1 
ATOM   5946 C  CB  . ALA C 1 174 ? -28.368 8.824   0.967   1    51.79  ? 344 ALA B CB  1 
ATOM   5947 N  N   . ASP C 1 175 ? -30.572 9.506   -1.284  1    46.11  ? 345 ASP B N   1 
ATOM   5948 C  CA  . ASP C 1 175 ? -31.894 9.574   -1.868  1    47.85  ? 345 ASP B CA  1 
ATOM   5949 C  C   . ASP C 1 175 ? -31.706 9.415   -3.368  1    47.89  ? 345 ASP B C   1 
ATOM   5950 O  O   . ASP C 1 175 ? -31.156 10.316  -3.977  1    51.45  ? 345 ASP B O   1 
ATOM   5951 C  CB  . ASP C 1 175 ? -32.542 10.921  -1.607  1    49.64  ? 345 ASP B CB  1 
ATOM   5952 C  CG  . ASP C 1 175 ? -33.963 11.086  -2.134  1    49.25  ? 345 ASP B CG  1 
ATOM   5953 O  OD1 . ASP C 1 175 ? -34.439 10.176  -2.816  1    46.94  ? 345 ASP B OD1 1 
ATOM   5954 O  OD2 . ASP C 1 175 ? -34.592 12.137  -1.859  1    51.5   ? 345 ASP B OD2 1 
ATOM   5955 N  N   . PRO C 1 176 ? -32.183 8.334   -4.028  1    48.27  ? 346 PRO B N   1 
ATOM   5956 C  CA  . PRO C 1 176 ? -33.016 7.302   -3.389  1    48.12  ? 346 PRO B CA  1 
ATOM   5957 C  C   . PRO C 1 176 ? -32.454 5.972   -2.909  1    46.7   ? 346 PRO B C   1 
ATOM   5958 O  O   . PRO C 1 176 ? -33.237 5.152   -2.444  1    50.3   ? 346 PRO B O   1 
ATOM   5959 C  CB  . PRO C 1 176 ? -33.954 6.985   -4.577  1    49.3   ? 346 PRO B CB  1 
ATOM   5960 C  CG  . PRO C 1 176 ? -33.008 6.993   -5.781  1    48.95  ? 346 PRO B CG  1 
ATOM   5961 C  CD  . PRO C 1 176 ? -32.026 8.126   -5.484  1    44.39  ? 346 PRO B CD  1 
ATOM   5962 N  N   . TYR C 1 177 ? -31.142 5.743   -3.047  1    43.81  ? 347 TYR B N   1 
ATOM   5963 C  CA  . TYR C 1 177 ? -30.62  4.377   -3.075  1    41.41  ? 347 TYR B CA  1 
ATOM   5964 C  C   . TYR C 1 177 ? -30.651 3.7     -1.702  1    43.72  ? 347 TYR B C   1 
ATOM   5965 O  O   . TYR C 1 177 ? -30.456 2.492   -1.611  1    48.36  ? 347 TYR B O   1 
ATOM   5966 C  CB  . TYR C 1 177 ? -29.327 4.222   -3.891  1    39.31  ? 347 TYR B CB  1 
ATOM   5967 C  CG  . TYR C 1 177 ? -29.585 4.5     -5.366  1    43.72  ? 347 TYR B CG  1 
ATOM   5968 C  CD1 . TYR C 1 177 ? -30.288 3.59    -6.167  1    43.67  ? 347 TYR B CD1 1 
ATOM   5969 C  CD2 . TYR C 1 177 ? -29.238 5.725   -5.925  1    44.48  ? 347 TYR B CD2 1 
ATOM   5970 C  CE1 . TYR C 1 177 ? -30.59  3.867   -7.496  1    42.97  ? 347 TYR B CE1 1 
ATOM   5971 C  CE2 . TYR C 1 177 ? -29.53  6.006   -7.251  1    46.72  ? 347 TYR B CE2 1 
ATOM   5972 C  CZ  . TYR C 1 177 ? -30.201 5.082   -8.038  1    45.21  ? 347 TYR B CZ  1 
ATOM   5973 O  OH  . TYR C 1 177 ? -30.477 5.43    -9.332  1    44.96  ? 347 TYR B OH  1 
ATOM   5974 N  N   . LEU C 1 178 ? -30.904 4.448   -0.625  1    44.35  ? 348 LEU B N   1 
ATOM   5975 C  CA  . LEU C 1 178 ? -30.953 3.805   0.679   1    46.47  ? 348 LEU B CA  1 
ATOM   5976 C  C   . LEU C 1 178 ? -32.152 2.863   0.797   1    48.76  ? 348 LEU B C   1 
ATOM   5977 O  O   . LEU C 1 178 ? -32.147 1.994   1.666   1    48.91  ? 348 LEU B O   1 
ATOM   5978 C  CB  . LEU C 1 178 ? -30.992 4.824   1.813   1    48.25  ? 348 LEU B CB  1 
ATOM   5979 C  CG  . LEU C 1 178 ? -29.656 5.391   2.28    1    45.42  ? 348 LEU B CG  1 
ATOM   5980 C  CD1 . LEU C 1 178 ? -29.917 6.222   3.523   1    40.92  ? 348 LEU B CD1 1 
ATOM   5981 C  CD2 . LEU C 1 178 ? -28.63  4.285   2.528   1    41.38  ? 348 LEU B CD2 1 
ATOM   5982 N  N   . LYS C 1 179 ? -33.186 3.05    -0.035  1    50.46  ? 349 LYS B N   1 
ATOM   5983 C  CA  . LYS C 1 179 ? -34.379 2.223   0.109   1    52.8   ? 349 LYS B CA  1 
ATOM   5984 C  C   . LYS C 1 179 ? -34.233 0.878   -0.589  1    51.51  ? 349 LYS B C   1 
ATOM   5985 O  O   . LYS C 1 179 ? -35.111 0.033   -0.474  1    60.59  ? 349 LYS B O   1 
ATOM   5986 C  CB  . LYS C 1 179 ? -35.697 2.92    -0.245  1    56.54  ? 349 LYS B CB  1 
ATOM   5987 C  CG  . LYS C 1 179 ? -35.825 3.696   -1.552  1    58.73  ? 349 LYS B CG  1 
ATOM   5988 C  CD  . LYS C 1 179 ? -36.94  4.744   -1.41   1    64.26  ? 349 LYS B CD  1 
ATOM   5989 C  CE  . LYS C 1 179 ? -36.946 5.852   -2.431  1    67.61  ? 349 LYS B CE  1 
ATOM   5990 N  NZ  . LYS C 1 179 ? -37.438 5.396   -3.733  1    63.05  ? 349 LYS B NZ  1 
ATOM   5991 N  N   . TYR C 1 180 ? -33.113 0.664   -1.278  1    47.98  ? 350 TYR B N   1 
ATOM   5992 C  CA  . TYR C 1 180 ? -32.919 -0.583  -1.994  1    45.63  ? 350 TYR B CA  1 
ATOM   5993 C  C   . TYR C 1 180 ? -31.791 -1.361  -1.33   1    45.2   ? 350 TYR B C   1 
ATOM   5994 O  O   . TYR C 1 180 ? -30.768 -0.789  -0.947  1    44.9   ? 350 TYR B O   1 
ATOM   5995 C  CB  . TYR C 1 180 ? -32.66  -0.304  -3.478  1    46.38  ? 350 TYR B CB  1 
ATOM   5996 C  CG  . TYR C 1 180 ? -33.735 0.486   -4.217  1    47     ? 350 TYR B CG  1 
ATOM   5997 C  CD1 . TYR C 1 180 ? -35.024 -0.023  -4.381  1    43.71  ? 350 TYR B CD1 1 
ATOM   5998 C  CD2 . TYR C 1 180 ? -33.445 1.736   -4.767  1    44.63  ? 350 TYR B CD2 1 
ATOM   5999 C  CE1 . TYR C 1 180 ? -35.991 0.691   -5.075  1    46.8   ? 350 TYR B CE1 1 
ATOM   6000 C  CE2 . TYR C 1 180 ? -34.403 2.46    -5.463  1    45.31  ? 350 TYR B CE2 1 
ATOM   6001 C  CZ  . TYR C 1 180 ? -35.682 1.936   -5.616  1    47.24  ? 350 TYR B CZ  1 
ATOM   6002 O  OH  . TYR C 1 180 ? -36.613 2.642   -6.326  1    44.21  ? 350 TYR B OH  1 
ATOM   6003 N  N   . LEU C 1 181 ? -32     -2.676  -1.213  1    49.02  ? 351 LEU B N   1 
ATOM   6004 C  CA  . LEU C 1 181 ? -31.003 -3.615  -0.711  1    46.61  ? 351 LEU B CA  1 
ATOM   6005 C  C   . LEU C 1 181 ? -29.874 -3.752  -1.721  1    41.76  ? 351 LEU B C   1 
ATOM   6006 O  O   . LEU C 1 181 ? -30.057 -3.621  -2.921  1    45.38  ? 351 LEU B O   1 
ATOM   6007 C  CB  . LEU C 1 181 ? -31.66  -4.976  -0.474  1    50.32  ? 351 LEU B CB  1 
ATOM   6008 C  CG  . LEU C 1 181 ? -32.655 -5.063  0.696   1    48.24  ? 351 LEU B CG  1 
ATOM   6009 C  CD1 . LEU C 1 181 ? -33.327 -6.414  0.755   1    43.16  ? 351 LEU B CD1 1 
ATOM   6010 C  CD2 . LEU C 1 181 ? -31.994 -4.747  2.042   1    45.05  ? 351 LEU B CD2 1 
ATOM   6011 N  N   . PRO C 1 182 ? -28.648 -4.035  -1.277  1    40.11  ? 352 PRO B N   1 
ATOM   6012 C  CA  . PRO C 1 182 ? -27.562 -4.324  -2.217  1    38.34  ? 352 PRO B CA  1 
ATOM   6013 C  C   . PRO C 1 182 ? -27.969 -5.245  -3.355  1    39.69  ? 352 PRO B C   1 
ATOM   6014 O  O   . PRO C 1 182 ? -27.613 -4.981  -4.498  1    38.89  ? 352 PRO B O   1 
ATOM   6015 C  CB  . PRO C 1 182 ? -26.56  -5.024  -1.314  1    37.61  ? 352 PRO B CB  1 
ATOM   6016 C  CG  . PRO C 1 182 ? -26.742 -4.324  0.006   1    36.18  ? 352 PRO B CG  1 
ATOM   6017 C  CD  . PRO C 1 182 ? -28.229 -3.989  0.13    1    37.08  ? 352 PRO B CD  1 
ATOM   6018 N  N   . SER C 1 183 ? -28.696 -6.321  -3.015  1    39.86  ? 353 SER B N   1 
ATOM   6019 C  CA  . SER C 1 183 ? -29.002 -7.399  -3.945  1    37.89  ? 353 SER B CA  1 
ATOM   6020 C  C   . SER C 1 183 ? -29.867 -6.901  -5.104  1    40.12  ? 353 SER B C   1 
ATOM   6021 O  O   . SER C 1 183 ? -29.735 -7.435  -6.21   1    42.27  ? 353 SER B O   1 
ATOM   6022 C  CB  . SER C 1 183 ? -29.649 -8.582  -3.252  1    37.25  ? 353 SER B CB  1 
ATOM   6023 O  OG  . SER C 1 183 ? -30.993 -8.305  -2.896  1    38.81  ? 353 SER B OG  1 
ATOM   6024 N  N   . VAL C 1 184 ? -30.734 -5.902  -4.831  1    35.48  ? 354 VAL B N   1 
ATOM   6025 C  CA  . VAL C 1 184 ? -31.66  -5.338  -5.794  1    34.43  ? 354 VAL B CA  1 
ATOM   6026 C  C   . VAL C 1 184 ? -30.943 -4.302  -6.667  1    39.8   ? 354 VAL B C   1 
ATOM   6027 O  O   . VAL C 1 184 ? -31.044 -4.337  -7.898  1    39.72  ? 354 VAL B O   1 
ATOM   6028 C  CB  . VAL C 1 184 ? -32.912 -4.775  -5.091  1    37.14  ? 354 VAL B CB  1 
ATOM   6029 C  CG1 . VAL C 1 184 ? -33.711 -3.858  -6.003  1    35.15  ? 354 VAL B CG1 1 
ATOM   6030 C  CG2 . VAL C 1 184 ? -33.833 -5.888  -4.565  1    35.05  ? 354 VAL B CG2 1 
ATOM   6031 N  N   . ILE C 1 185 ? -30.173 -3.391  -6.049  1    39.08  ? 355 ILE B N   1 
ATOM   6032 C  CA  . ILE C 1 185 ? -29.386 -2.455  -6.839  1    40.35  ? 355 ILE B CA  1 
ATOM   6033 C  C   . ILE C 1 185 ? -28.461 -3.201  -7.804  1    40.83  ? 355 ILE B C   1 
ATOM   6034 O  O   . ILE C 1 185 ? -28.325 -2.813  -8.965  1    41.11  ? 355 ILE B O   1 
ATOM   6035 C  CB  . ILE C 1 185 ? -28.583 -1.48   -5.968  1    42.6   ? 355 ILE B CB  1 
ATOM   6036 C  CG1 . ILE C 1 185 ? -29.512 -0.69   -5.044  1    41.17  ? 355 ILE B CG1 1 
ATOM   6037 C  CG2 . ILE C 1 185 ? -27.741 -0.557  -6.861  1    37.91  ? 355 ILE B CG2 1 
ATOM   6038 C  CD1 . ILE C 1 185 ? -28.776 0.018   -3.918  1    35.81  ? 355 ILE B CD1 1 
ATOM   6039 N  N   . ALA C 1 186 ? -27.83  -4.27   -7.318  1    39.1   ? 356 ALA B N   1 
ATOM   6040 C  CA  . ALA C 1 186 ? -26.965 -5.1    -8.145  1    38.98  ? 356 ALA B CA  1 
ATOM   6041 C  C   . ALA C 1 186 ? -27.74  -5.696  -9.319  1    40.34  ? 356 ALA B C   1 
ATOM   6042 O  O   . ALA C 1 186 ? -27.231 -5.755  -10.436 1    46.35  ? 356 ALA B O   1 
ATOM   6043 C  CB  . ALA C 1 186 ? -26.333 -6.179  -7.293  1    37.54  ? 356 ALA B CB  1 
ATOM   6044 N  N   . ALA C 1 187 ? -28.985 -6.105  -9.061  1    36.15  ? 357 ALA B N   1 
ATOM   6045 C  CA  . ALA C 1 187 ? -29.791 -6.728  -10.086 1    36.85  ? 357 ALA B CA  1 
ATOM   6046 C  C   . ALA C 1 187 ? -30.09  -5.687  -11.147 1    40.64  ? 357 ALA B C   1 
ATOM   6047 O  O   . ALA C 1 187 ? -29.957 -5.953  -12.342 1    44.32  ? 357 ALA B O   1 
ATOM   6048 C  CB  . ALA C 1 187 ? -31.069 -7.262  -9.486  1    37.21  ? 357 ALA B CB  1 
ATOM   6049 N  N   . ALA C 1 188 ? -30.531 -4.512  -10.687 1    40.47  ? 358 ALA B N   1 
ATOM   6050 C  CA  . ALA C 1 188 ? -30.906 -3.453  -11.598 1    39.53  ? 358 ALA B CA  1 
ATOM   6051 C  C   . ALA C 1 188 ? -29.687 -3.119  -12.451 1    44.42  ? 358 ALA B C   1 
ATOM   6052 O  O   . ALA C 1 188 ? -29.797 -3.044  -13.677 1    46.34  ? 358 ALA B O   1 
ATOM   6053 C  CB  . ALA C 1 188 ? -31.398 -2.259  -10.833 1    37.64  ? 358 ALA B CB  1 
ATOM   6054 N  N   . ALA C 1 189 ? -28.526 -2.979  -11.785 1    42.59  ? 359 ALA B N   1 
ATOM   6055 C  CA  . ALA C 1 189 ? -27.278 -2.61   -12.436 1    38.19  ? 359 ALA B CA  1 
ATOM   6056 C  C   . ALA C 1 189 ? -26.916 -3.659  -13.474 1    38.72  ? 359 ALA B C   1 
ATOM   6057 O  O   . ALA C 1 189 ? -26.573 -3.314  -14.607 1    39.4   ? 359 ALA B O   1 
ATOM   6058 C  CB  . ALA C 1 189 ? -26.162 -2.449  -11.427 1    34.98  ? 359 ALA B CB  1 
ATOM   6059 N  N   . PHE C 1 190 ? -27.012 -4.937  -13.08  1    37.82  ? 360 PHE B N   1 
ATOM   6060 C  CA  . PHE C 1 190 ? -26.669 -6.001  -14.008 1    38.77  ? 360 PHE B CA  1 
ATOM   6061 C  C   . PHE C 1 190 ? -27.555 -5.933  -15.251 1    41.25  ? 360 PHE B C   1 
ATOM   6062 O  O   . PHE C 1 190 ? -27.037 -6.087  -16.353 1    46.58  ? 360 PHE B O   1 
ATOM   6063 C  CB  . PHE C 1 190 ? -26.719 -7.381  -13.358 1    39.21  ? 360 PHE B CB  1 
ATOM   6064 C  CG  . PHE C 1 190 ? -26.313 -8.489  -14.321 1    40.76  ? 360 PHE B CG  1 
ATOM   6065 C  CD1 . PHE C 1 190 ? -25.003 -8.582  -14.783 1    39.24  ? 360 PHE B CD1 1 
ATOM   6066 C  CD2 . PHE C 1 190 ? -27.234 -9.45   -14.727 1    42.61  ? 360 PHE B CD2 1 
ATOM   6067 C  CE1 . PHE C 1 190 ? -24.63  -9.604  -15.641 1    41.13  ? 360 PHE B CE1 1 
ATOM   6068 C  CE2 . PHE C 1 190 ? -26.848 -10.484 -15.574 1    43.5   ? 360 PHE B CE2 1 
ATOM   6069 C  CZ  . PHE C 1 190 ? -25.552 -10.554 -16.035 1    41.95  ? 360 PHE B CZ  1 
ATOM   6070 N  N   . HIS C 1 191 ? -28.87  -5.677  -15.076 1    40.59  ? 361 HIS B N   1 
ATOM   6071 C  CA  . HIS C 1 191 ? -29.823 -5.721  -16.179 1    40.72  ? 361 HIS B CA  1 
ATOM   6072 C  C   . HIS C 1 191 ? -29.624 -4.515  -17.084 1    41.96  ? 361 HIS B C   1 
ATOM   6073 O  O   . HIS C 1 191 ? -29.654 -4.629  -18.315 1    42.46  ? 361 HIS B O   1 
ATOM   6074 C  CB  . HIS C 1 191 ? -31.292 -5.713  -15.738 1    39.35  ? 361 HIS B CB  1 
ATOM   6075 C  CG  . HIS C 1 191 ? -32.168 -5.313  -16.886 1    40.9   ? 361 HIS B CG  1 
ATOM   6076 N  ND1 . HIS C 1 191 ? -32.494 -6.19   -17.9   1    40.83  ? 361 HIS B ND1 1 
ATOM   6077 C  CD2 . HIS C 1 191 ? -32.724 -4.115  -17.227 1    40.31  ? 361 HIS B CD2 1 
ATOM   6078 C  CE1 . HIS C 1 191 ? -33.257 -5.559  -18.785 1    44.07  ? 361 HIS B CE1 1 
ATOM   6079 N  NE2 . HIS C 1 191 ? -33.409 -4.3    -18.391 1    43.19  ? 361 HIS B NE2 1 
ATOM   6080 N  N   . LEU C 1 192 ? -29.427 -3.358  -16.443 1    41.75  ? 362 LEU B N   1 
ATOM   6081 C  CA  . LEU C 1 192 ? -29.184 -2.145  -17.196 1    42.72  ? 362 LEU B CA  1 
ATOM   6082 C  C   . LEU C 1 192 ? -27.915 -2.303  -18.035 1    47.95  ? 362 LEU B C   1 
ATOM   6083 O  O   . LEU C 1 192 ? -27.913 -1.953  -19.216 1    50.98  ? 362 LEU B O   1 
ATOM   6084 C  CB  . LEU C 1 192 ? -29.109 -0.966  -16.249 1    39.43  ? 362 LEU B CB  1 
ATOM   6085 C  CG  . LEU C 1 192 ? -29.179 0.393   -16.932 1    42.76  ? 362 LEU B CG  1 
ATOM   6086 C  CD1 . LEU C 1 192 ? -30.301 0.4     -17.942 1    43.43  ? 362 LEU B CD1 1 
ATOM   6087 C  CD2 . LEU C 1 192 ? -29.372 1.47    -15.873 1    42.51  ? 362 LEU B CD2 1 
ATOM   6088 N  N   . ALA C 1 193 ? -26.854 -2.858  -17.437 1    44.13  ? 363 ALA B N   1 
ATOM   6089 C  CA  . ALA C 1 193 ? -25.594 -2.971  -18.153 1    47.99  ? 363 ALA B CA  1 
ATOM   6090 C  C   . ALA C 1 193 ? -25.743 -3.908  -19.345 1    49.84  ? 363 ALA B C   1 
ATOM   6091 O  O   . ALA C 1 193 ? -25.352 -3.568  -20.473 1    53.75  ? 363 ALA B O   1 
ATOM   6092 C  CB  . ALA C 1 193 ? -24.505 -3.427  -17.223 1    48.06  ? 363 ALA B CB  1 
ATOM   6093 N  N   . LEU C 1 194 ? -26.323 -5.079  -19.068 1    48.42  ? 364 LEU B N   1 
ATOM   6094 C  CA  . LEU C 1 194 ? -26.593 -6.097  -20.07  1    49.75  ? 364 LEU B CA  1 
ATOM   6095 C  C   . LEU C 1 194 ? -27.386 -5.521  -21.242 1    48.96  ? 364 LEU B C   1 
ATOM   6096 O  O   . LEU C 1 194 ? -26.999 -5.729  -22.394 1    52.45  ? 364 LEU B O   1 
ATOM   6097 C  CB  . LEU C 1 194 ? -27.373 -7.217  -19.379 1    53     ? 364 LEU B CB  1 
ATOM   6098 C  CG  . LEU C 1 194 ? -27.495 -8.548  -20.124 1    54.63  ? 364 LEU B CG  1 
ATOM   6099 C  CD1 . LEU C 1 194 ? -26.14  -9.08   -20.561 1    55.78  ? 364 LEU B CD1 1 
ATOM   6100 C  CD2 . LEU C 1 194 ? -28.153 -9.496  -19.142 1    57.43  ? 364 LEU B CD2 1 
ATOM   6101 N  N   . TYR C 1 195 ? -28.481 -4.805  -20.943 1    44.63  ? 365 TYR B N   1 
ATOM   6102 C  CA  . TYR C 1 195 ? -29.335 -4.242  -21.974 1    45.57  ? 365 TYR B CA  1 
ATOM   6103 C  C   . TYR C 1 195 ? -28.561 -3.221  -22.809 1    46.78  ? 365 TYR B C   1 
ATOM   6104 O  O   . TYR C 1 195 ? -28.538 -3.32   -24.022 1    49.12  ? 365 TYR B O   1 
ATOM   6105 C  CB  . TYR C 1 195 ? -30.623 -3.686  -21.36  1    44.64  ? 365 TYR B CB  1 
ATOM   6106 C  CG  . TYR C 1 195 ? -31.613 -3.111  -22.362 1    47.86  ? 365 TYR B CG  1 
ATOM   6107 C  CD1 . TYR C 1 195 ? -32.36  -3.939  -23.193 1    50.7   ? 365 TYR B CD1 1 
ATOM   6108 C  CD2 . TYR C 1 195 ? -31.823 -1.744  -22.463 1    49.37  ? 365 TYR B CD2 1 
ATOM   6109 C  CE1 . TYR C 1 195 ? -33.28  -3.433  -24.093 1    53.5   ? 365 TYR B CE1 1 
ATOM   6110 C  CE2 . TYR C 1 195 ? -32.755 -1.224  -23.345 1    53.74  ? 365 TYR B CE2 1 
ATOM   6111 C  CZ  . TYR C 1 195 ? -33.481 -2.064  -24.172 1    58.11  ? 365 TYR B CZ  1 
ATOM   6112 O  OH  . TYR C 1 195 ? -34.381 -1.536  -25.074 1    67.25  ? 365 TYR B OH  1 
ATOM   6113 N  N   . THR C 1 196 ? -27.912 -2.256  -22.154 1    48.25  ? 366 THR B N   1 
ATOM   6114 C  CA  . THR C 1 196 ? -27.137 -1.196  -22.793 1    51.56  ? 366 THR B CA  1 
ATOM   6115 C  C   . THR C 1 196 ? -26.111 -1.759  -23.778 1    53.93  ? 366 THR B C   1 
ATOM   6116 O  O   . THR C 1 196 ? -25.974 -1.221  -24.877 1    62.55  ? 366 THR B O   1 
ATOM   6117 C  CB  . THR C 1 196 ? -26.422 -0.329  -21.751 1    50.83  ? 366 THR B CB  1 
ATOM   6118 O  OG1 . THR C 1 196 ? -27.356 0.215   -20.817 1    52.1   ? 366 THR B OG1 1 
ATOM   6119 C  CG2 . THR C 1 196 ? -25.586 0.768   -22.387 1    46.48  ? 366 THR B CG2 1 
ATOM   6120 N  N   . VAL C 1 197 ? -25.382 -2.814  -23.385 1    50.89  ? 367 VAL B N   1 
ATOM   6121 C  CA  . VAL C 1 197 ? -24.258 -3.297  -24.175 1    49.34  ? 367 VAL B CA  1 
ATOM   6122 C  C   . VAL C 1 197 ? -24.712 -4.292  -25.235 1    49.05  ? 367 VAL B C   1 
ATOM   6123 O  O   . VAL C 1 197 ? -24.149 -4.298  -26.324 1    53.1   ? 367 VAL B O   1 
ATOM   6124 C  CB  . VAL C 1 197 ? -23.137 -3.918  -23.321 1    49.1   ? 367 VAL B CB  1 
ATOM   6125 C  CG1 . VAL C 1 197 ? -22.139 -4.685  -24.184 1    46.35  ? 367 VAL B CG1 1 
ATOM   6126 C  CG2 . VAL C 1 197 ? -22.432 -2.868  -22.478 1    45.79  ? 367 VAL B CG2 1 
ATOM   6127 N  N   . THR C 1 198 ? -25.698 -5.142  -24.91  1    48.41  ? 368 THR B N   1 
ATOM   6128 C  CA  . THR C 1 198 ? -26.002 -6.3    -25.746 1    49.2   ? 368 THR B CA  1 
ATOM   6129 C  C   . THR C 1 198 ? -27.459 -6.363  -26.172 1    50.32  ? 368 THR B C   1 
ATOM   6130 O  O   . THR C 1 198 ? -27.807 -7.247  -26.952 1    51.49  ? 368 THR B O   1 
ATOM   6131 C  CB  . THR C 1 198 ? -25.711 -7.632  -25.063 1    49.03  ? 368 THR B CB  1 
ATOM   6132 O  OG1 . THR C 1 198 ? -26.81  -7.86   -24.183 1    50.79  ? 368 THR B OG1 1 
ATOM   6133 C  CG2 . THR C 1 198 ? -24.353 -7.696  -24.395 1    47.12  ? 368 THR B CG2 1 
ATOM   6134 N  N   . GLY C 1 199 ? -28.316 -5.516  -25.595 1    52.16  ? 369 GLY B N   1 
ATOM   6135 C  CA  . GLY C 1 199 ? -29.741 -5.581  -25.881 1    54.75  ? 369 GLY B CA  1 
ATOM   6136 C  C   . GLY C 1 199 ? -30.48  -6.637  -25.05  1    61.86  ? 369 GLY B C   1 
ATOM   6137 O  O   . GLY C 1 199 ? -31.707 -6.645  -25.038 1    72.52  ? 369 GLY B O   1 
ATOM   6138 N  N   . GLN C 1 200 ? -29.765 -7.527  -24.348 1    58.99  ? 370 GLN B N   1 
ATOM   6139 C  CA  . GLN C 1 200 ? -30.438 -8.626  -23.675 1    61.21  ? 370 GLN B CA  1 
ATOM   6140 C  C   . GLN C 1 200 ? -30.933 -8.14   -22.321 1    60.38  ? 370 GLN B C   1 
ATOM   6141 O  O   . GLN C 1 200 ? -30.563 -7.046  -21.895 1    61.09  ? 370 GLN B O   1 
ATOM   6142 C  CB  . GLN C 1 200 ? -29.506 -9.808  -23.428 1    65.86  ? 370 GLN B CB  1 
ATOM   6143 C  CG  . GLN C 1 200 ? -29.032 -10.518 -24.689 1    72.83  ? 370 GLN B CG  1 
ATOM   6144 C  CD  . GLN C 1 200 ? -27.915 -11.481 -24.36  1    82.8   ? 370 GLN B CD  1 
ATOM   6145 O  OE1 . GLN C 1 200 ? -28.111 -12.698 -24.34  1    88.83  ? 370 GLN B OE1 1 
ATOM   6146 N  NE2 . GLN C 1 200 ? -26.75  -10.948 -24.017 1    84.29  ? 370 GLN B NE2 1 
ATOM   6147 N  N   . SER C 1 201 ? -31.734 -8.985  -21.657 1    58.14  ? 371 SER B N   1 
ATOM   6148 C  CA  . SER C 1 201 ? -32.384 -8.647  -20.403 1    52.42  ? 371 SER B CA  1 
ATOM   6149 C  C   . SER C 1 201 ? -31.973 -9.618  -19.316 1    54.16  ? 371 SER B C   1 
ATOM   6150 O  O   . SER C 1 201 ? -31.315 -10.617 -19.587 1    57.36  ? 371 SER B O   1 
ATOM   6151 C  CB  . SER C 1 201 ? -33.856 -8.647  -20.537 1    50.12  ? 371 SER B CB  1 
ATOM   6152 O  OG  . SER C 1 201 ? -34.22  -7.549  -21.352 1    57.04  ? 371 SER B OG  1 
ATOM   6153 N  N   . TRP C 1 202 ? -32.342 -9.242  -18.088 1    57.99  ? 372 TRP B N   1 
ATOM   6154 C  CA  . TRP C 1 202 ? -32.321 -10.055 -16.883 1    54.35  ? 372 TRP B CA  1 
ATOM   6155 C  C   . TRP C 1 202 ? -32.697 -11.489 -17.241 1    54.06  ? 372 TRP B C   1 
ATOM   6156 O  O   . TRP C 1 202 ? -33.834 -11.757 -17.636 1    52.37  ? 372 TRP B O   1 
ATOM   6157 C  CB  . TRP C 1 202 ? -33.299 -9.447  -15.862 1    50.75  ? 372 TRP B CB  1 
ATOM   6158 C  CG  . TRP C 1 202 ? -33.29  -10.073 -14.491 1    48.43  ? 372 TRP B CG  1 
ATOM   6159 C  CD1 . TRP C 1 202 ? -34.319 -10.775 -13.936 1    47.06  ? 372 TRP B CD1 1 
ATOM   6160 C  CD2 . TRP C 1 202 ? -32.225 -10.057 -13.509 1    44.53  ? 372 TRP B CD2 1 
ATOM   6161 N  NE1 . TRP C 1 202 ? -33.974 -11.191 -12.677 1    48.46  ? 372 TRP B NE1 1 
ATOM   6162 C  CE2 . TRP C 1 202 ? -32.703 -10.763 -12.384 1    46.25  ? 372 TRP B CE2 1 
ATOM   6163 C  CE3 . TRP C 1 202 ? -30.934 -9.518  -13.457 1    44.2   ? 372 TRP B CE3 1 
ATOM   6164 C  CZ2 . TRP C 1 202 ? -31.935 -10.943 -11.236 1    43.25  ? 372 TRP B CZ2 1 
ATOM   6165 C  CZ3 . TRP C 1 202 ? -30.171 -9.689  -12.319 1    43.82  ? 372 TRP B CZ3 1 
ATOM   6166 C  CH2 . TRP C 1 202 ? -30.667 -10.403 -11.229 1    44.01  ? 372 TRP B CH2 1 
ATOM   6167 N  N   . PRO C 1 203 ? -31.765 -12.46  -17.027 1    49.51  ? 373 PRO B N   1 
ATOM   6168 C  CA  . PRO C 1 203 ? -32.021 -13.847 -17.378 1    50.65  ? 373 PRO B CA  1 
ATOM   6169 C  C   . PRO C 1 203 ? -32.88  -14.656 -16.43  1    48.32  ? 373 PRO B C   1 
ATOM   6170 O  O   . PRO C 1 203 ? -32.886 -14.402 -15.221 1    49.32  ? 373 PRO B O   1 
ATOM   6171 C  CB  . PRO C 1 203 ? -30.59  -14.38  -17.434 1    48.57  ? 373 PRO B CB  1 
ATOM   6172 C  CG  . PRO C 1 203 ? -29.896 -13.722 -16.294 1    48.92  ? 373 PRO B CG  1 
ATOM   6173 C  CD  . PRO C 1 203 ? -30.406 -12.316 -16.439 1    46.12  ? 373 PRO B CD  1 
ATOM   6174 N  N   . GLU C 1 204 ? -33.581 -15.643 -16.978 1    46.55  ? 374 GLU B N   1 
ATOM   6175 C  CA  . GLU C 1 204 ? -34.476 -16.493 -16.155 1    51.43  ? 374 GLU B CA  1 
ATOM   6176 C  C   . GLU C 1 204 ? -33.637 -17.288 -15.157 1    49.8   ? 374 GLU B C   1 
ATOM   6177 O  O   . GLU C 1 204 ? -34.153 -17.597 -14.081 1    49.44  ? 374 GLU B O   1 
ATOM   6178 C  CB  . GLU C 1 204 ? -35.324 -17.397 -17.049 1    57.54  ? 374 GLU B CB  1 
ATOM   6179 C  CG  . GLU C 1 204 ? -36.333 -18.264 -16.302 1    71.92  ? 374 GLU B CG  1 
ATOM   6180 C  CD  . GLU C 1 204 ? -35.737 -19.509 -15.675 1    77.05  ? 374 GLU B CD  1 
ATOM   6181 O  OE1 . GLU C 1 204 ? -34.695 -19.977 -16.17  1    77.01  ? 374 GLU B OE1 1 
ATOM   6182 O  OE2 . GLU C 1 204 ? -36.316 -20.01  -14.692 1    85.28  ? 374 GLU B OE2 1 
ATOM   6183 N  N   . SER C 1 205 ? -32.399 -17.601 -15.52  1    46.74  ? 375 SER B N   1 
ATOM   6184 C  CA  . SER C 1 205 ? -31.497 -18.312 -14.593 1    43.78  ? 375 SER B CA  1 
ATOM   6185 C  C   . SER C 1 205 ? -31.397 -17.487 -13.31  1    44.77  ? 375 SER B C   1 
ATOM   6186 O  O   . SER C 1 205 ? -31.328 -18.076 -12.223 1    42.54  ? 375 SER B O   1 
ATOM   6187 C  CB  . SER C 1 205 ? -30.159 -18.52  -15.221 1    41.22  ? 375 SER B CB  1 
ATOM   6188 O  OG  . SER C 1 205 ? -29.532 -17.284 -15.517 1    41.21  ? 375 SER B OG  1 
ATOM   6189 N  N   . LEU C 1 206 ? -31.411 -16.166 -13.457 1    43.68  ? 376 LEU B N   1 
ATOM   6190 C  CA  . LEU C 1 206 ? -31.25  -15.324 -12.282 1    42.74  ? 376 LEU B CA  1 
ATOM   6191 C  C   . LEU C 1 206 ? -32.6   -15.023 -11.631 1    45.14  ? 376 LEU B C   1 
ATOM   6192 O  O   . LEU C 1 206 ? -32.656 -14.638 -10.463 1    44.48  ? 376 LEU B O   1 
ATOM   6193 C  CB  . LEU C 1 206 ? -30.522 -14.038 -12.664 1    41.31  ? 376 LEU B CB  1 
ATOM   6194 C  CG  . LEU C 1 206 ? -28.994 -14.134 -12.744 1    43.68  ? 376 LEU B CG  1 
ATOM   6195 C  CD1 . LEU C 1 206 ? -28.386 -12.811 -13.174 1    41.77  ? 376 LEU B CD1 1 
ATOM   6196 C  CD2 . LEU C 1 206 ? -28.383 -14.569 -11.421 1    40.89  ? 376 LEU B CD2 1 
ATOM   6197 N  N   . VAL C 1 207 ? -33.681 -15.162 -12.408 1    46.24  ? 377 VAL B N   1 
ATOM   6198 C  CA  . VAL C 1 207 ? -35     -15.254 -11.805 1    47.06  ? 377 VAL B CA  1 
ATOM   6199 C  C   . VAL C 1 207 ? -35.035 -16.483 -10.893 1    46.26  ? 377 VAL B C   1 
ATOM   6200 O  O   . VAL C 1 207 ? -35.524 -16.418 -9.775  1    48.19  ? 377 VAL B O   1 
ATOM   6201 C  CB  . VAL C 1 207 ? -36.118 -15.253 -12.872 1    48.75  ? 377 VAL B CB  1 
ATOM   6202 C  CG1 . VAL C 1 207 ? -37.5   -15.49  -12.276 1    46.61  ? 377 VAL B CG1 1 
ATOM   6203 C  CG2 . VAL C 1 207 ? -36.116 -13.979 -13.704 1    44.6   ? 377 VAL B CG2 1 
ATOM   6204 N  N   . GLN C 1 208 ? -34.487 -17.611 -11.352 1    49.72  ? 378 GLN B N   1 
ATOM   6205 C  CA  . GLN C 1 208 ? -34.492 -18.851 -10.578 1    48.85  ? 378 GLN B CA  1 
ATOM   6206 C  C   . GLN C 1 208 ? -33.73  -18.638 -9.273  1    46.93  ? 378 GLN B C   1 
ATOM   6207 O  O   . GLN C 1 208 ? -34.208 -19.053 -8.22   1    46.32  ? 378 GLN B O   1 
ATOM   6208 C  CB  . GLN C 1 208 ? -33.961 -20.075 -11.34  1    47.54  ? 378 GLN B CB  1 
ATOM   6209 C  CG  . GLN C 1 208 ? -34.784 -20.523 -12.55  1    50.24  ? 378 GLN B CG  1 
ATOM   6210 C  CD  . GLN C 1 208 ? -36.11  -21.151 -12.173 1    56.39  ? 378 GLN B CD  1 
ATOM   6211 O  OE1 . GLN C 1 208 ? -37.148 -20.985 -12.839 1    53.63  ? 378 GLN B OE1 1 
ATOM   6212 N  NE2 . GLN C 1 208 ? -36.058 -21.918 -11.09  1    60.14  ? 378 GLN B NE2 1 
ATOM   6213 N  N   . LYS C 1 209 ? -32.558 -17.983 -9.359  1    43.91  ? 379 LYS B N   1 
ATOM   6214 C  CA  . LYS C 1 209 ? -31.663 -17.885 -8.221  1    43.16  ? 379 LYS B CA  1 
ATOM   6215 C  C   . LYS C 1 209 ? -32.211 -16.877 -7.206  1    42.73  ? 379 LYS B C   1 
ATOM   6216 O  O   . LYS C 1 209 ? -32.178 -17.12  -5.991  1    39.99  ? 379 LYS B O   1 
ATOM   6217 C  CB  . LYS C 1 209 ? -30.245 -17.568 -8.713  1    43.61  ? 379 LYS B CB  1 
ATOM   6218 C  CG  . LYS C 1 209 ? -29.149 -17.499 -7.667  1    46.26  ? 379 LYS B CG  1 
ATOM   6219 C  CD  . LYS C 1 209 ? -27.895 -16.782 -8.167  1    53.6   ? 379 LYS B CD  1 
ATOM   6220 C  CE  . LYS C 1 209 ? -26.74  -16.702 -7.195  1    53.05  ? 379 LYS B CE  1 
ATOM   6221 N  NZ  . LYS C 1 209 ? -26.307 -18.038 -6.772  1    57.88  ? 379 LYS B NZ  1 
ATOM   6222 N  N   . THR C 1 210 ? -32.705 -15.733 -7.71   1    43.14  ? 380 THR B N   1 
ATOM   6223 C  CA  . THR C 1 210 ? -32.951 -14.571 -6.854  1    43.95  ? 380 THR B CA  1 
ATOM   6224 C  C   . THR C 1 210 ? -34.418 -14.454 -6.444  1    44.66  ? 380 THR B C   1 
ATOM   6225 O  O   . THR C 1 210 ? -34.711 -13.802 -5.433  1    49.05  ? 380 THR B O   1 
ATOM   6226 C  CB  . THR C 1 210 ? -32.474 -13.26  -7.496  1    42.58  ? 380 THR B CB  1 
ATOM   6227 O  OG1 . THR C 1 210 ? -33.263 -12.927 -8.642  1    40.99  ? 380 THR B OG1 1 
ATOM   6228 C  CG2 . THR C 1 210 ? -30.998 -13.321 -7.833  1    36.61  ? 380 THR B CG2 1 
ATOM   6229 N  N   . GLY C 1 211 ? -35.324 -15.025 -7.251  1    40.79  ? 381 GLY B N   1 
ATOM   6230 C  CA  . GLY C 1 211 ? -36.747 -14.761 -7.121  1    40.3   ? 381 GLY B CA  1 
ATOM   6231 C  C   . GLY C 1 211 ? -37.186 -13.425 -7.74   1    41.1   ? 381 GLY B C   1 
ATOM   6232 O  O   . GLY C 1 211 ? -38.378 -13.138 -7.803  1    42.89  ? 381 GLY B O   1 
ATOM   6233 N  N   . TYR C 1 212 ? -36.237 -12.595 -8.194  1    40.79  ? 382 TYR B N   1 
ATOM   6234 C  CA  . TYR C 1 212 ? -36.573 -11.293 -8.746  1    41.32  ? 382 TYR B CA  1 
ATOM   6235 C  C   . TYR C 1 212 ? -36.865 -11.344 -10.249 1    43.36  ? 382 TYR B C   1 
ATOM   6236 O  O   . TYR C 1 212 ? -36.187 -12.033 -11.003 1    44.03  ? 382 TYR B O   1 
ATOM   6237 C  CB  . TYR C 1 212 ? -35.397 -10.338 -8.636  1    40.56  ? 382 TYR B CB  1 
ATOM   6238 C  CG  . TYR C 1 212 ? -34.848 -10.07  -7.245  1    43.27  ? 382 TYR B CG  1 
ATOM   6239 C  CD1 . TYR C 1 212 ? -35.644 -10.114 -6.09   1    38.55  ? 382 TYR B CD1 1 
ATOM   6240 C  CD2 . TYR C 1 212 ? -33.497 -9.718  -7.124  1    39.84  ? 382 TYR B CD2 1 
ATOM   6241 C  CE1 . TYR C 1 212 ? -35.075 -9.811  -4.858  1    37.59  ? 382 TYR B CE1 1 
ATOM   6242 C  CE2 . TYR C 1 212 ? -32.936 -9.405  -5.902  1    38.87  ? 382 TYR B CE2 1 
ATOM   6243 C  CZ  . TYR C 1 212 ? -33.727 -9.462  -4.764  1    41.15  ? 382 TYR B CZ  1 
ATOM   6244 O  OH  . TYR C 1 212 ? -33.044 -9.17   -3.609  1    43.63  ? 382 TYR B OH  1 
ATOM   6245 N  N   . THR C 1 213 ? -37.865 -10.555 -10.676 1    45.03  ? 383 THR B N   1 
ATOM   6246 C  CA  . THR C 1 213 ? -38.228 -10.376 -12.074 1    47.77  ? 383 THR B CA  1 
ATOM   6247 C  C   . THR C 1 213 ? -37.986 -8.916  -12.44  1    51.55  ? 383 THR B C   1 
ATOM   6248 O  O   . THR C 1 213 ? -37.702 -8.103  -11.551 1    55.58  ? 383 THR B O   1 
ATOM   6249 C  CB  . THR C 1 213 ? -39.71  -10.709 -12.247 1    48.6   ? 383 THR B CB  1 
ATOM   6250 O  OG1 . THR C 1 213 ? -40.422 -9.732  -11.488 1    47.76  ? 383 THR B OG1 1 
ATOM   6251 C  CG2 . THR C 1 213 ? -40.042 -12.135 -11.836 1    47.15  ? 383 THR B CG2 1 
ATOM   6252 N  N   . LEU C 1 214 ? -38.152 -8.583  -13.726 1    48.62  ? 384 LEU B N   1 
ATOM   6253 C  CA  . LEU C 1 214 ? -38.167 -7.179  -14.102 1    50.94  ? 384 LEU B CA  1 
ATOM   6254 C  C   . LEU C 1 214 ? -39.266 -6.42   -13.374 1    53.53  ? 384 LEU B C   1 
ATOM   6255 O  O   . LEU C 1 214 ? -39.083 -5.237  -13.105 1    56.15  ? 384 LEU B O   1 
ATOM   6256 C  CB  . LEU C 1 214 ? -38.258 -6.916  -15.596 1    53.38  ? 384 LEU B CB  1 
ATOM   6257 C  CG  . LEU C 1 214 ? -37.005 -7.276  -16.391 1    55.4   ? 384 LEU B CG  1 
ATOM   6258 C  CD1 . LEU C 1 214 ? -37.242 -6.912  -17.838 1    56.42  ? 384 LEU B CD1 1 
ATOM   6259 C  CD2 . LEU C 1 214 ? -35.825 -6.537  -15.799 1    51.03  ? 384 LEU B CD2 1 
ATOM   6260 N  N   . GLU C 1 215 ? -40.406 -7.075  -13.1   1    58.6   ? 385 GLU B N   1 
ATOM   6261 C  CA  . GLU C 1 215 ? -41.461 -6.421  -12.331 1    60.19  ? 385 GLU B CA  1 
ATOM   6262 C  C   . GLU C 1 215 ? -40.894 -5.927  -11.003 1    57.68  ? 385 GLU B C   1 
ATOM   6263 O  O   . GLU C 1 215 ? -40.962 -4.728  -10.724 1    53.2   ? 385 GLU B O   1 
ATOM   6264 C  CB  . GLU C 1 215 ? -42.668 -7.292  -12.01  1    60.77  ? 385 GLU B CB  1 
ATOM   6265 C  CG  . GLU C 1 215 ? -43.536 -7.534  -13.235 1    77.22  ? 385 GLU B CG  1 
ATOM   6266 C  CD  . GLU C 1 215 ? -44.955 -7.943  -12.867 1    92.62  ? 385 GLU B CD  1 
ATOM   6267 O  OE1 . GLU C 1 215 ? -45.776 -8.147  -13.802 1    91.41  ? 385 GLU B OE1 1 
ATOM   6268 O  OE2 . GLU C 1 215 ? -45.239 -8.039  -11.641 1    91.9   ? 385 GLU B OE2 1 
ATOM   6269 N  N   . THR C 1 216 ? -40.305 -6.848  -10.224 1    52.32  ? 386 THR B N   1 
ATOM   6270 C  CA  . THR C 1 216 ? -39.875 -6.514  -8.879  1    54.09  ? 386 THR B CA  1 
ATOM   6271 C  C   . THR C 1 216 ? -38.734 -5.496  -8.938  1    54.23  ? 386 THR B C   1 
ATOM   6272 O  O   . THR C 1 216 ? -38.672 -4.617  -8.086  1    57.57  ? 386 THR B O   1 
ATOM   6273 C  CB  . THR C 1 216 ? -39.604 -7.741  -7.992  1    55.32  ? 386 THR B CB  1 
ATOM   6274 O  OG1 . THR C 1 216 ? -38.34  -8.304  -8.319  1    51.46  ? 386 THR B OG1 1 
ATOM   6275 C  CG2 . THR C 1 216 ? -40.703 -8.794  -8.034  1    56.29  ? 386 THR B CG2 1 
ATOM   6276 N  N   . LEU C 1 217 ? -37.881 -5.563  -9.975  1    55.69  ? 387 LEU B N   1 
ATOM   6277 C  CA  . LEU C 1 217 ? -36.74  -4.658  -10.12  1    51.64  ? 387 LEU B CA  1 
ATOM   6278 C  C   . LEU C 1 217 ? -37.125 -3.281  -10.677 1    54.46  ? 387 LEU B C   1 
ATOM   6279 O  O   . LEU C 1 217 ? -36.319 -2.363  -10.593 1    53.13  ? 387 LEU B O   1 
ATOM   6280 C  CB  . LEU C 1 217 ? -35.697 -5.298  -11.028 1    47.38  ? 387 LEU B CB  1 
ATOM   6281 C  CG  . LEU C 1 217 ? -35.084 -6.605  -10.525 1    46.54  ? 387 LEU B CG  1 
ATOM   6282 C  CD1 . LEU C 1 217 ? -34.177 -7.16   -11.609 1    45.53  ? 387 LEU B CD1 1 
ATOM   6283 C  CD2 . LEU C 1 217 ? -34.298 -6.369  -9.25   1    39.94  ? 387 LEU B CD2 1 
ATOM   6284 N  N   . LYS C 1 218 ? -38.324 -3.155  -11.269 1    53.28  ? 388 LYS B N   1 
ATOM   6285 C  CA  . LYS C 1 218 ? -38.771 -1.997  -12.037 1    50.67  ? 388 LYS B CA  1 
ATOM   6286 C  C   . LYS C 1 218 ? -38.527 -0.67   -11.316 1    50.89  ? 388 LYS B C   1 
ATOM   6287 O  O   . LYS C 1 218 ? -38.016 0.269   -11.921 1    54.84  ? 388 LYS B O   1 
ATOM   6288 C  CB  . LYS C 1 218 ? -40.238 -2.146  -12.456 1    49.41  ? 388 LYS B CB  1 
ATOM   6289 C  CG  . LYS C 1 218 ? -40.718 -1.089  -13.426 1    50.36  ? 388 LYS B CG  1 
ATOM   6290 C  CD  . LYS C 1 218 ? -42.155 -1.215  -13.909 1    53.2   ? 388 LYS B CD  1 
ATOM   6291 C  CE  . LYS C 1 218 ? -42.491 -0.118  -14.885 1    57.63  ? 388 LYS B CE  1 
ATOM   6292 N  NZ  . LYS C 1 218 ? -43.845 -0.231  -15.444 1    59.13  ? 388 LYS B NZ  1 
ATOM   6293 N  N   . PRO C 1 219 ? -38.943 -0.473  -10.05  1    51.25  ? 389 PRO B N   1 
ATOM   6294 C  CA  . PRO C 1 219 ? -38.641 0.784   -9.359  1    51.5   ? 389 PRO B CA  1 
ATOM   6295 C  C   . PRO C 1 219 ? -37.169 1.202   -9.359  1    49.8   ? 389 PRO B C   1 
ATOM   6296 O  O   . PRO C 1 219 ? -36.811 2.317   -9.76   1    51.4   ? 389 PRO B O   1 
ATOM   6297 C  CB  . PRO C 1 219 ? -39.217 0.574   -7.935  1    49.26  ? 389 PRO B CB  1 
ATOM   6298 C  CG  . PRO C 1 219 ? -40.323 -0.441  -8.14   1    47.93  ? 389 PRO B CG  1 
ATOM   6299 C  CD  . PRO C 1 219 ? -39.832 -1.349  -9.27   1    51.57  ? 389 PRO B CD  1 
ATOM   6300 N  N   . CYS C 1 220 ? -36.317 0.303   -8.876  1    48.06  ? 390 CYS B N   1 
ATOM   6301 C  CA  . CYS C 1 220 ? -34.883 0.537   -8.816  1    47.72  ? 390 CYS B CA  1 
ATOM   6302 C  C   . CYS C 1 220 ? -34.336 0.901   -10.209 1    50.78  ? 390 CYS B C   1 
ATOM   6303 O  O   . CYS C 1 220 ? -33.639 1.904   -10.361 1    52.82  ? 390 CYS B O   1 
ATOM   6304 C  CB  . CYS C 1 220 ? -34.238 -0.671  -8.163  1    42.87  ? 390 CYS B CB  1 
ATOM   6305 S  SG  . CYS C 1 220 ? -32.514 -0.383  -7.722  1    45.42  ? 390 CYS B SG  1 
ATOM   6306 N  N   . LEU C 1 221 ? -34.69  0.101   -11.23  1    48.77  ? 391 LEU B N   1 
ATOM   6307 C  CA  . LEU C 1 221 ? -34.325 0.294   -12.624 1    48.69  ? 391 LEU B CA  1 
ATOM   6308 C  C   . LEU C 1 221 ? -34.62  1.718   -13.075 1    51.4   ? 391 LEU B C   1 
ATOM   6309 O  O   . LEU C 1 221 ? -33.808 2.301   -13.796 1    52.43  ? 391 LEU B O   1 
ATOM   6310 C  CB  . LEU C 1 221 ? -35.18  -0.672  -13.436 1    54.97  ? 391 LEU B CB  1 
ATOM   6311 C  CG  . LEU C 1 221 ? -34.999 -2.182  -13.266 1    56.95  ? 391 LEU B CG  1 
ATOM   6312 C  CD1 . LEU C 1 221 ? -36.024 -2.972  -14.038 1    55.73  ? 391 LEU B CD1 1 
ATOM   6313 C  CD2 . LEU C 1 221 ? -33.598 -2.488  -13.805 1    53.77  ? 391 LEU B CD2 1 
ATOM   6314 N  N   . LEU C 1 222 ? -35.816 2.228   -12.742 1    51.09  ? 392 LEU B N   1 
ATOM   6315 C  CA  . LEU C 1 222 ? -36.242 3.534   -13.226 1    52.37  ? 392 LEU B CA  1 
ATOM   6316 C  C   . LEU C 1 222 ? -35.373 4.64    -12.624 1    54.6   ? 392 LEU B C   1 
ATOM   6317 O  O   . LEU C 1 222 ? -35.071 5.624   -13.299 1    60.22  ? 392 LEU B O   1 
ATOM   6318 C  CB  . LEU C 1 222 ? -37.71  3.79    -12.901 1    52.16  ? 392 LEU B CB  1 
ATOM   6319 C  CG  . LEU C 1 222 ? -38.753 3.046   -13.74  1    55.69  ? 392 LEU B CG  1 
ATOM   6320 C  CD1 . LEU C 1 222 ? -40.131 3.539   -13.27  1    55.16  ? 392 LEU B CD1 1 
ATOM   6321 C  CD2 . LEU C 1 222 ? -38.583 3.256   -15.239 1    54.2   ? 392 LEU B CD2 1 
ATOM   6322 N  N   . ASP C 1 223 ? -35.005 4.48    -11.346 1    49.11  ? 393 ASP B N   1 
ATOM   6323 C  CA  . ASP C 1 223 ? -34.137 5.417   -10.661 1    46.51  ? 393 ASP B CA  1 
ATOM   6324 C  C   . ASP C 1 223 ? -32.72  5.287   -11.206 1    45.61  ? 393 ASP B C   1 
ATOM   6325 O  O   . ASP C 1 223 ? -32.069 6.293   -11.475 1    45.46  ? 393 ASP B O   1 
ATOM   6326 C  CB  . ASP C 1 223 ? -34.119 5.217   -9.148  1    47.93  ? 393 ASP B CB  1 
ATOM   6327 C  CG  . ASP C 1 223 ? -35.369 5.637   -8.392  1    48.67  ? 393 ASP B CG  1 
ATOM   6328 O  OD1 . ASP C 1 223 ? -36.013 6.618   -8.823  1    54.07  ? 393 ASP B OD1 1 
ATOM   6329 O  OD2 . ASP C 1 223 ? -35.677 4.989   -7.373  1    47.33  ? 393 ASP B OD2 1 
ATOM   6330 N  N   . LEU C 1 224 ? -32.24  4.045   -11.342 1    44.11  ? 394 LEU B N   1 
ATOM   6331 C  CA  . LEU C 1 224 ? -30.86  3.803   -11.749 1    43.67  ? 394 LEU B CA  1 
ATOM   6332 C  C   . LEU C 1 224 ? -30.662 4.321   -13.172 1    48.5   ? 394 LEU B C   1 
ATOM   6333 O  O   . LEU C 1 224 ? -29.598 4.834   -13.515 1    50.06  ? 394 LEU B O   1 
ATOM   6334 C  CB  . LEU C 1 224 ? -30.497 2.323   -11.649 1    40.4   ? 394 LEU B CB  1 
ATOM   6335 C  CG  . LEU C 1 224 ? -28.995 2.021   -11.694 1    39.7   ? 394 LEU B CG  1 
ATOM   6336 C  CD1 . LEU C 1 224 ? -28.274 2.72    -10.538 1    39.64  ? 394 LEU B CD1 1 
ATOM   6337 C  CD2 . LEU C 1 224 ? -28.707 0.515   -11.683 1    34.83  ? 394 LEU B CD2 1 
ATOM   6338 N  N   . HIS C 1 225 ? -31.722 4.203   -13.98  1    45.66  ? 395 HIS B N   1 
ATOM   6339 C  CA  . HIS C 1 225 ? -31.671 4.62    -15.36  1    46.4   ? 395 HIS B CA  1 
ATOM   6340 C  C   . HIS C 1 225 ? -31.616 6.145   -15.43  1    51.16  ? 395 HIS B C   1 
ATOM   6341 O  O   . HIS C 1 225 ? -31.003 6.68    -16.345 1    57.06  ? 395 HIS B O   1 
ATOM   6342 C  CB  . HIS C 1 225 ? -32.823 3.97    -16.121 1    44.15  ? 395 HIS B CB  1 
ATOM   6343 C  CG  . HIS C 1 225 ? -33.018 4.472   -17.492 1    46.97  ? 395 HIS B CG  1 
ATOM   6344 N  ND1 . HIS C 1 225 ? -32.011 4.41    -18.426 1    49.63  ? 395 HIS B ND1 1 
ATOM   6345 C  CD2 . HIS C 1 225 ? -34.091 4.997   -18.129 1    50.52  ? 395 HIS B CD2 1 
ATOM   6346 C  CE1 . HIS C 1 225 ? -32.467 4.882   -19.588 1    51.45  ? 395 HIS B CE1 1 
ATOM   6347 N  NE2 . HIS C 1 225 ? -33.732 5.229   -19.441 1    50.47  ? 395 HIS B NE2 1 
ATOM   6348 N  N   . GLN C 1 226 ? -32.281 6.846   -14.502 1    51.12  ? 396 GLN B N   1 
ATOM   6349 C  CA  . GLN C 1 226 ? -32.191 8.297   -14.44  1    53.77  ? 396 GLN B CA  1 
ATOM   6350 C  C   . GLN C 1 226 ? -30.796 8.7     -13.971 1    54.75  ? 396 GLN B C   1 
ATOM   6351 O  O   . GLN C 1 226 ? -30.177 9.602   -14.546 1    54.4   ? 396 GLN B O   1 
ATOM   6352 C  CB  . GLN C 1 226 ? -33.294 8.924   -13.592 1    59.59  ? 396 GLN B CB  1 
ATOM   6353 C  CG  . GLN C 1 226 ? -34.526 9.311   -14.405 1    78.41  ? 396 GLN B CG  1 
ATOM   6354 C  CD  . GLN C 1 226 ? -35.594 10.061  -13.629 1    95.89  ? 396 GLN B CD  1 
ATOM   6355 O  OE1 . GLN C 1 226 ? -36.637 10.43   -14.185 1    114.99 ? 396 GLN B OE1 1 
ATOM   6356 N  NE2 . GLN C 1 226 ? -35.369 10.269  -12.336 1    92.72  ? 396 GLN B NE2 1 
ATOM   6357 N  N   . THR C 1 227 ? -30.29  7.994   -12.95  1    53     ? 397 THR B N   1 
ATOM   6358 C  CA  . THR C 1 227 ? -28.969 8.305   -12.442 1    52.06  ? 397 THR B CA  1 
ATOM   6359 C  C   . THR C 1 227 ? -27.952 8.213   -13.578 1    51.87  ? 397 THR B C   1 
ATOM   6360 O  O   . THR C 1 227 ? -27.13  9.111   -13.71  1    55.81  ? 397 THR B O   1 
ATOM   6361 C  CB  . THR C 1 227 ? -28.611 7.434   -11.246 1    51.65  ? 397 THR B CB  1 
ATOM   6362 O  OG1 . THR C 1 227 ? -29.514 7.88    -10.237 1    51.31  ? 397 THR B OG1 1 
ATOM   6363 C  CG2 . THR C 1 227 ? -27.161 7.636   -10.827 1    48.49  ? 397 THR B CG2 1 
ATOM   6364 N  N   . TYR C 1 228 ? -28.065 7.174   -14.421 1    50.73  ? 398 TYR B N   1 
ATOM   6365 C  CA  . TYR C 1 228 ? -27.211 6.956   -15.587 1    49.92  ? 398 TYR B CA  1 
ATOM   6366 C  C   . TYR C 1 228 ? -27.358 8.088   -16.605 1    52.06  ? 398 TYR B C   1 
ATOM   6367 O  O   . TYR C 1 228 ? -26.356 8.649   -17.039 1    58.13  ? 398 TYR B O   1 
ATOM   6368 C  CB  . TYR C 1 228 ? -27.49  5.572   -16.179 1    46.95  ? 398 TYR B CB  1 
ATOM   6369 C  CG  . TYR C 1 228 ? -26.484 5.045   -17.187 1    51.35  ? 398 TYR B CG  1 
ATOM   6370 C  CD1 . TYR C 1 228 ? -25.273 5.692   -17.442 1    52.91  ? 398 TYR B CD1 1 
ATOM   6371 C  CD2 . TYR C 1 228 ? -26.743 3.868   -17.879 1    52.17  ? 398 TYR B CD2 1 
ATOM   6372 C  CE1 . TYR C 1 228 ? -24.366 5.197   -18.367 1    53.21  ? 398 TYR B CE1 1 
ATOM   6373 C  CE2 . TYR C 1 228 ? -25.845 3.369   -18.809 1    51.99  ? 398 TYR B CE2 1 
ATOM   6374 C  CZ  . TYR C 1 228 ? -24.652 4.027   -19.054 1    54.36  ? 398 TYR B CZ  1 
ATOM   6375 O  OH  . TYR C 1 228 ? -23.787 3.482   -19.968 1    54.15  ? 398 TYR B OH  1 
ATOM   6376 N  N   . LEU C 1 229 ? -28.596 8.446   -16.965 1    51.01  ? 399 LEU B N   1 
ATOM   6377 C  CA  . LEU C 1 229 ? -28.857 9.53    -17.895 1    51.65  ? 399 LEU B CA  1 
ATOM   6378 C  C   . LEU C 1 229 ? -28.228 10.828  -17.397 1    53.56  ? 399 LEU B C   1 
ATOM   6379 O  O   . LEU C 1 229 ? -27.667 11.575  -18.189 1    56.59  ? 399 LEU B O   1 
ATOM   6380 C  CB  . LEU C 1 229 ? -30.347 9.7     -18.18  1    52.99  ? 399 LEU B CB  1 
ATOM   6381 C  CG  . LEU C 1 229 ? -30.973 8.667   -19.129 1    56.2   ? 399 LEU B CG  1 
ATOM   6382 C  CD1 . LEU C 1 229 ? -32.394 9.027   -19.482 1    57.07  ? 399 LEU B CD1 1 
ATOM   6383 C  CD2 . LEU C 1 229 ? -30.197 8.477   -20.423 1    56.01  ? 399 LEU B CD2 1 
ATOM   6384 N  N   . ARG C 1 230 ? -28.312 11.094  -16.093 1    54.09  ? 400 ARG B N   1 
ATOM   6385 C  CA  . ARG C 1 230 ? -27.91  12.389  -15.569 1    58.53  ? 400 ARG B CA  1 
ATOM   6386 C  C   . ARG C 1 230 ? -26.434 12.42   -15.167 1    56.65  ? 400 ARG B C   1 
ATOM   6387 O  O   . ARG C 1 230 ? -25.925 13.475  -14.775 1    57.91  ? 400 ARG B O   1 
ATOM   6388 C  CB  . ARG C 1 230 ? -28.798 12.781  -14.381 1    63.97  ? 400 ARG B CB  1 
ATOM   6389 C  CG  . ARG C 1 230 ? -30.246 13.087  -14.756 1    75.76  ? 400 ARG B CG  1 
ATOM   6390 C  CD  . ARG C 1 230 ? -31.16  13.044  -13.538 1    86.02  ? 400 ARG B CD  1 
ATOM   6391 N  NE  . ARG C 1 230 ? -32.571 13.362  -13.784 1    103.2  ? 400 ARG B NE  1 
ATOM   6392 C  CZ  . ARG C 1 230 ? -33.488 13.524  -12.824 1    110.67 ? 400 ARG B CZ  1 
ATOM   6393 N  NH1 . ARG C 1 230 ? -33.215 13.21   -11.562 1    99.59  ? 400 ARG B NH1 1 
ATOM   6394 N  NH2 . ARG C 1 230 ? -34.693 13.973  -13.142 1    106.07 ? 400 ARG B NH2 1 
ATOM   6395 N  N   . ALA C 1 231 ? -25.737 11.284  -15.261 1    49.5   ? 401 ALA B N   1 
ATOM   6396 C  CA  . ALA C 1 231 ? -24.435 11.182  -14.609 1    49.85  ? 401 ALA B CA  1 
ATOM   6397 C  C   . ALA C 1 231 ? -23.442 12.277  -15.059 1    50.97  ? 401 ALA B C   1 
ATOM   6398 O  O   . ALA C 1 231 ? -22.672 12.802  -14.26  1    52.09  ? 401 ALA B O   1 
ATOM   6399 C  CB  . ALA C 1 231 ? -23.893 9.768   -14.727 1    43.88  ? 401 ALA B CB  1 
ATOM   6400 N  N   . PRO C 1 232 ? -23.373 12.679  -16.342 1    50.83  ? 402 PRO B N   1 
ATOM   6401 C  CA  . PRO C 1 232 ? -22.479 13.776  -16.712 1    53.06  ? 402 PRO B CA  1 
ATOM   6402 C  C   . PRO C 1 232 ? -22.819 15.13   -16.089 1    55.58  ? 402 PRO B C   1 
ATOM   6403 O  O   . PRO C 1 232 ? -22.011 16.048  -16.161 1    57.75  ? 402 PRO B O   1 
ATOM   6404 C  CB  . PRO C 1 232 ? -22.579 13.841  -18.255 1    51.82  ? 402 PRO B CB  1 
ATOM   6405 C  CG  . PRO C 1 232 ? -23.282 12.565  -18.682 1    50.15  ? 402 PRO B CG  1 
ATOM   6406 C  CD  . PRO C 1 232 ? -24.07  12.081  -17.495 1    50.2   ? 402 PRO B CD  1 
ATOM   6407 N  N   . GLN C 1 233 ? -24.026 15.267  -15.531 1    56.32  ? 403 GLN B N   1 
ATOM   6408 C  CA  . GLN C 1 233 ? -24.497 16.523  -14.953 1    61.89  ? 403 GLN B CA  1 
ATOM   6409 C  C   . GLN C 1 233 ? -24.34  16.534  -13.424 1    62.28  ? 403 GLN B C   1 
ATOM   6410 O  O   . GLN C 1 233 ? -24.387 17.596  -12.816 1    63.06  ? 403 GLN B O   1 
ATOM   6411 C  CB  . GLN C 1 233 ? -25.972 16.78   -15.29  1    66.03  ? 403 GLN B CB  1 
ATOM   6412 C  CG  . GLN C 1 233 ? -26.266 17.35   -16.676 1    77.5   ? 403 GLN B CG  1 
ATOM   6413 C  CD  . GLN C 1 233 ? -25.725 16.557  -17.854 1    85.31  ? 403 GLN B CD  1 
ATOM   6414 O  OE1 . GLN C 1 233 ? -24.899 17.061  -18.633 1    83.41  ? 403 GLN B OE1 1 
ATOM   6415 N  NE2 . GLN C 1 233 ? -26.192 15.319  -18.018 1    80.46  ? 403 GLN B NE2 1 
ATOM   6416 N  N   . HIS C 1 234 ? -24.178 15.363  -12.787 1    59.48  ? 404 HIS B N   1 
ATOM   6417 C  CA  . HIS C 1 234 ? -24.115 15.302  -11.333 1    57.37  ? 404 HIS B CA  1 
ATOM   6418 C  C   . HIS C 1 234 ? -22.972 16.205  -10.879 1    59.25  ? 404 HIS B C   1 
ATOM   6419 O  O   . HIS C 1 234 ? -22.027 16.411  -11.632 1    61.95  ? 404 HIS B O   1 
ATOM   6420 C  CB  . HIS C 1 234 ? -23.847 13.866  -10.871 1    51.8   ? 404 HIS B CB  1 
ATOM   6421 C  CG  . HIS C 1 234 ? -24.221 13.567  -9.458  1    52.08  ? 404 HIS B CG  1 
ATOM   6422 N  ND1 . HIS C 1 234 ? -23.522 13.999  -8.354  1    51.91  ? 404 HIS B ND1 1 
ATOM   6423 C  CD2 . HIS C 1 234 ? -25.228 12.808  -8.968  1    50.55  ? 404 HIS B CD2 1 
ATOM   6424 C  CE1 . HIS C 1 234 ? -24.095 13.512  -7.248  1    49.08  ? 404 HIS B CE1 1 
ATOM   6425 N  NE2 . HIS C 1 234 ? -25.136 12.797  -7.6    1    45.7   ? 404 HIS B NE2 1 
ATOM   6426 N  N   . ALA C 1 235 ? -23.068 16.73   -9.655  1    57.37  ? 405 ALA B N   1 
ATOM   6427 C  CA  . ALA C 1 235 ? -22.009 17.518  -9.035  1    53.63  ? 405 ALA B CA  1 
ATOM   6428 C  C   . ALA C 1 235 ? -20.759 16.678  -8.724  1    53.2   ? 405 ALA B C   1 
ATOM   6429 O  O   . ALA C 1 235 ? -19.666 17.213  -8.574  1    53.86  ? 405 ALA B O   1 
ATOM   6430 C  CB  . ALA C 1 235 ? -22.58  18.128  -7.777  1    48.78  ? 405 ALA B CB  1 
ATOM   6431 N  N   . GLN C 1 236 ? -20.927 15.358  -8.576  1    49.76  ? 406 GLN B N   1 
ATOM   6432 C  CA  . GLN C 1 236 ? -19.834 14.448  -8.279  1    48.25  ? 406 GLN B CA  1 
ATOM   6433 C  C   . GLN C 1 236 ? -19.455 13.644  -9.52   1    50.59  ? 406 GLN B C   1 
ATOM   6434 O  O   . GLN C 1 236 ? -20.311 13.035  -10.159 1    51.77  ? 406 GLN B O   1 
ATOM   6435 C  CB  . GLN C 1 236 ? -20.233 13.534  -7.124  1    45.34  ? 406 GLN B CB  1 
ATOM   6436 C  CG  . GLN C 1 236 ? -19.999 14.15   -5.748  1    49.11  ? 406 GLN B CG  1 
ATOM   6437 C  CD  . GLN C 1 236 ? -20.914 15.309  -5.402  1    53.46  ? 406 GLN B CD  1 
ATOM   6438 O  OE1 . GLN C 1 236 ? -22.145 15.188  -5.388  1    54.93  ? 406 GLN B OE1 1 
ATOM   6439 N  NE2 . GLN C 1 236 ? -20.313 16.446  -5.08   1    56.3   ? 406 GLN B NE2 1 
ATOM   6440 N  N   . GLN C 1 237 ? -18.147 13.607  -9.812  1    51.01  ? 407 GLN B N   1 
ATOM   6441 C  CA  . GLN C 1 237 ? -17.636 13.104  -11.076 1    50.2   ? 407 GLN B CA  1 
ATOM   6442 C  C   . GLN C 1 237 ? -16.505 12.09   -10.887 1    49.71  ? 407 GLN B C   1 
ATOM   6443 O  O   . GLN C 1 237 ? -15.984 11.57   -11.869 1    52.26  ? 407 GLN B O   1 
ATOM   6444 C  CB  . GLN C 1 237 ? -17.206 14.305  -11.922 1    49.46  ? 407 GLN B CB  1 
ATOM   6445 C  CG  . GLN C 1 237 ? -18.356 15.164  -12.445 1    49.09  ? 407 GLN B CG  1 
ATOM   6446 C  CD  . GLN C 1 237 ? -19.197 14.478  -13.505 1    49.59  ? 407 GLN B CD  1 
ATOM   6447 O  OE1 . GLN C 1 237 ? -18.645 13.88   -14.43  1    53.94  ? 407 GLN B OE1 1 
ATOM   6448 N  NE2 . GLN C 1 237 ? -20.522 14.529  -13.401 1    45.67  ? 407 GLN B NE2 1 
ATOM   6449 N  N   . SER C 1 238 ? -16.154 11.767  -9.644  1    49.72  ? 408 SER B N   1 
ATOM   6450 C  CA  . SER C 1 238 ? -14.988 10.931  -9.378  1    51.97  ? 408 SER B CA  1 
ATOM   6451 C  C   . SER C 1 238 ? -15.188 9.492   -9.861  1    48.81  ? 408 SER B C   1 
ATOM   6452 O  O   . SER C 1 238 ? -14.211 8.821   -10.183 1    50.57  ? 408 SER B O   1 
ATOM   6453 C  CB  . SER C 1 238 ? -14.601 10.953  -7.913  1    50.58  ? 408 SER B CB  1 
ATOM   6454 O  OG  . SER C 1 238 ? -14.214 12.263  -7.527  1    50.4   ? 408 SER B OG  1 
ATOM   6455 N  N   . ILE C 1 239 ? -16.441 9.029   -9.91   1    42.97  ? 409 ILE B N   1 
ATOM   6456 C  CA  . ILE C 1 239 ? -16.732 7.699   -10.422 1    42.1   ? 409 ILE B CA  1 
ATOM   6457 C  C   . ILE C 1 239 ? -16.66  7.692   -11.956 1    45.39  ? 409 ILE B C   1 
ATOM   6458 O  O   . ILE C 1 239 ? -16.132 6.755   -12.58  1    44.4   ? 409 ILE B O   1 
ATOM   6459 C  CB  . ILE C 1 239 ? -18.081 7.189   -9.883  1    40.25  ? 409 ILE B CB  1 
ATOM   6460 C  CG1 . ILE C 1 239 ? -18.068 7.038   -8.368  1    36.71  ? 409 ILE B CG1 1 
ATOM   6461 C  CG2 . ILE C 1 239 ? -18.464 5.873   -10.549 1    41.9   ? 409 ILE B CG2 1 
ATOM   6462 C  CD1 . ILE C 1 239 ? -19.375 6.536   -7.791  1    34.89  ? 409 ILE B CD1 1 
ATOM   6463 N  N   . ARG C 1 240 ? -17.147 8.762   -12.592 1    44.66  ? 410 ARG B N   1 
ATOM   6464 C  CA  . ARG C 1 240 ? -17.008 8.819   -14.034 1    46.11  ? 410 ARG B CA  1 
ATOM   6465 C  C   . ARG C 1 240 ? -15.54  8.888   -14.446 1    50.57  ? 410 ARG B C   1 
ATOM   6466 O  O   . ARG C 1 240 ? -15.179 8.223   -15.416 1    51.59  ? 410 ARG B O   1 
ATOM   6467 C  CB  . ARG C 1 240 ? -17.787 9.967   -14.665 1    48.68  ? 410 ARG B CB  1 
ATOM   6468 C  CG  . ARG C 1 240 ? -19.254 9.62    -14.853 1    52.95  ? 410 ARG B CG  1 
ATOM   6469 C  CD  . ARG C 1 240 ? -20.054 10.74   -15.501 1    55.73  ? 410 ARG B CD  1 
ATOM   6470 N  NE  . ARG C 1 240 ? -19.814 10.708  -16.942 1    56.32  ? 410 ARG B NE  1 
ATOM   6471 C  CZ  . ARG C 1 240 ? -19.43  11.729  -17.684 1    56.68  ? 410 ARG B CZ  1 
ATOM   6472 N  NH1 . ARG C 1 240 ? -19.391 11.579  -18.984 1    59.11  ? 410 ARG B NH1 1 
ATOM   6473 N  NH2 . ARG C 1 240 ? -19.139 12.894  -17.15  1    53.13  ? 410 ARG B NH2 1 
ATOM   6474 N  N   . GLU C 1 241 ? -14.719 9.709   -13.754 1    51.61  ? 411 GLU B N   1 
ATOM   6475 C  CA  . GLU C 1 241 ? -13.312 9.849   -14.118 1    53.73  ? 411 GLU B CA  1 
ATOM   6476 C  C   . GLU C 1 241 ? -12.663 8.476   -14.002 1    52.09  ? 411 GLU B C   1 
ATOM   6477 O  O   . GLU C 1 241 ? -12.013 8.006   -14.925 1    55.62  ? 411 GLU B O   1 
ATOM   6478 C  CB  . GLU C 1 241 ? -12.482 10.822  -13.276 1    55.99  ? 411 GLU B CB  1 
ATOM   6479 C  CG  . GLU C 1 241 ? -12.922 12.289  -13.314 1    59.67  ? 411 GLU B CG  1 
ATOM   6480 C  CD  . GLU C 1 241 ? -13.015 12.938  -14.691 1    66.85  ? 411 GLU B CD  1 
ATOM   6481 O  OE1 . GLU C 1 241 ? -12.105 12.798  -15.544 1    68.4   ? 411 GLU B OE1 1 
ATOM   6482 O  OE2 . GLU C 1 241 ? -14.021 13.643  -14.904 1    70.94  ? 411 GLU B OE2 1 
ATOM   6483 N  N   . LYS C 1 242 ? -12.914 7.82    -12.873 1    49.37  ? 412 LYS B N   1 
ATOM   6484 C  CA  . LYS C 1 242 ? -12.329 6.524   -12.587 1    47.13  ? 412 LYS B CA  1 
ATOM   6485 C  C   . LYS C 1 242 ? -12.632 5.541   -13.722 1    48.38  ? 412 LYS B C   1 
ATOM   6486 O  O   . LYS C 1 242 ? -11.749 4.795   -14.142 1    48.81  ? 412 LYS B O   1 
ATOM   6487 C  CB  . LYS C 1 242 ? -12.804 6.047   -11.207 1    40.87  ? 412 LYS B CB  1 
ATOM   6488 C  CG  . LYS C 1 242 ? -12.645 4.554   -10.927 1    38.65  ? 412 LYS B CG  1 
ATOM   6489 C  CD  . LYS C 1 242 ? -13.213 4.196   -9.554  1    39.94  ? 412 LYS B CD  1 
ATOM   6490 C  CE  . LYS C 1 242 ? -13.083 2.787   -9.093  1    37.08  ? 412 LYS B CE  1 
ATOM   6491 N  NZ  . LYS C 1 242 ? -13.766 2.598   -7.809  1    37.95  ? 412 LYS B NZ  1 
ATOM   6492 N  N   . TYR C 1 243 ? -13.888 5.512   -14.177 1    46.74  ? 413 TYR B N   1 
ATOM   6493 C  CA  . TYR C 1 243 ? -14.31  4.495   -15.121 1    45.51  ? 413 TYR B CA  1 
ATOM   6494 C  C   . TYR C 1 243 ? -14.054 4.919   -16.571 1    47.61  ? 413 TYR B C   1 
ATOM   6495 O  O   . TYR C 1 243 ? -14.484 4.196   -17.461 1    51.21  ? 413 TYR B O   1 
ATOM   6496 C  CB  . TYR C 1 243 ? -15.751 4.03    -14.852 1    41.98  ? 413 TYR B CB  1 
ATOM   6497 C  CG  . TYR C 1 243 ? -15.908 3.014   -13.728 1    40.51  ? 413 TYR B CG  1 
ATOM   6498 C  CD1 . TYR C 1 243 ? -16.024 3.421   -12.403 1    40.18  ? 413 TYR B CD1 1 
ATOM   6499 C  CD2 . TYR C 1 243 ? -15.96  1.646   -13.984 1    39.9   ? 413 TYR B CD2 1 
ATOM   6500 C  CE1 . TYR C 1 243 ? -16.183 2.514   -11.368 1    37.23  ? 413 TYR B CE1 1 
ATOM   6501 C  CE2 . TYR C 1 243 ? -16.108 0.724   -12.959 1    39.6   ? 413 TYR B CE2 1 
ATOM   6502 C  CZ  . TYR C 1 243 ? -16.22  1.161   -11.649 1    39.55  ? 413 TYR B CZ  1 
ATOM   6503 O  OH  . TYR C 1 243 ? -16.346 0.269   -10.626 1    38.49  ? 413 TYR B OH  1 
ATOM   6504 N  N   . LYS C 1 244 ? -13.338 6.029   -16.832 1    47.78  ? 414 LYS B N   1 
ATOM   6505 C  CA  . LYS C 1 244 ? -12.71  6.24    -18.14  1    49.76  ? 414 LYS B CA  1 
ATOM   6506 C  C   . LYS C 1 244 ? -11.492 5.326   -18.313 1    53.07  ? 414 LYS B C   1 
ATOM   6507 O  O   . LYS C 1 244 ? -11.058 5.035   -19.431 1    58.59  ? 414 LYS B O   1 
ATOM   6508 C  CB  . LYS C 1 244 ? -12.195 7.666   -18.36  1    49.29  ? 414 LYS B CB  1 
ATOM   6509 C  CG  . LYS C 1 244 ? -13.302 8.674   -18.482 1    51.04  ? 414 LYS B CG  1 
ATOM   6510 C  CD  . LYS C 1 244 ? -12.838 10.114  -18.324 1    54.95  ? 414 LYS B CD  1 
ATOM   6511 C  CE  . LYS C 1 244 ? -14.044 10.995  -18.028 1    59.1   ? 414 LYS B CE  1 
ATOM   6512 N  NZ  . LYS C 1 244 ? -13.695 12.422  -18.006 1    68.43  ? 414 LYS B NZ  1 
ATOM   6513 N  N   . ASN C 1 245 ? -10.913 4.905   -17.188 1    53.02  ? 415 ASN B N   1 
ATOM   6514 C  CA  . ASN C 1 245 ? -9.707  4.103   -17.191 1    60.43  ? 415 ASN B CA  1 
ATOM   6515 C  C   . ASN C 1 245 ? -9.942  2.805   -17.952 1    60.58  ? 415 ASN B C   1 
ATOM   6516 O  O   . ASN C 1 245 ? -11.022 2.196   -17.883 1    58.85  ? 415 ASN B O   1 
ATOM   6517 C  CB  . ASN C 1 245 ? -9.274  3.734   -15.78  1    71.91  ? 415 ASN B CB  1 
ATOM   6518 C  CG  . ASN C 1 245 ? -7.834  3.28    -15.714 1    79.5   ? 415 ASN B CG  1 
ATOM   6519 O  OD1 . ASN C 1 245 ? -7.527  2.112   -15.978 1    80.59  ? 415 ASN B OD1 1 
ATOM   6520 N  ND2 . ASN C 1 245 ? -6.948  4.196   -15.346 1    79.21  ? 415 ASN B ND2 1 
ATOM   6521 N  N   . SER C 1 246 ? -8.876  2.375   -18.635 1    60.82  ? 416 SER B N   1 
ATOM   6522 C  CA  . SER C 1 246 ? -8.927  1.148   -19.401 1    61.85  ? 416 SER B CA  1 
ATOM   6523 C  C   . SER C 1 246 ? -9.06   -0.054  -18.469 1    57.87  ? 416 SER B C   1 
ATOM   6524 O  O   . SER C 1 246 ? -9.535  -1.083  -18.903 1    60.16  ? 416 SER B O   1 
ATOM   6525 C  CB  . SER C 1 246 ? -7.748  1.019   -20.307 1    64.75  ? 416 SER B CB  1 
ATOM   6526 O  OG  . SER C 1 246 ? -6.765  0.243   -19.642 1    75.11  ? 416 SER B OG  1 
ATOM   6527 N  N   . LYS C 1 247 ? -8.63   0.067   -17.209 1    56.7   ? 417 LYS B N   1 
ATOM   6528 C  CA  . LYS C 1 247 ? -8.838  -0.975  -16.213 1    61.33  ? 417 LYS B CA  1 
ATOM   6529 C  C   . LYS C 1 247 ? -10.309 -1.422  -16.22  1    62.5   ? 417 LYS B C   1 
ATOM   6530 O  O   . LYS C 1 247 ? -10.606 -2.61   -16.121 1    61.99  ? 417 LYS B O   1 
ATOM   6531 C  CB  . LYS C 1 247 ? -8.457  -0.515  -14.795 1    63.71  ? 417 LYS B CB  1 
ATOM   6532 C  CG  . LYS C 1 247 ? -8.078  -1.666  -13.848 1    71.2   ? 417 LYS B CG  1 
ATOM   6533 C  CD  . LYS C 1 247 ? -8.624  -1.708  -12.42  1    72.6   ? 417 LYS B CD  1 
ATOM   6534 C  CE  . LYS C 1 247 ? -8.094  -0.71   -11.426 1    81.32  ? 417 LYS B CE  1 
ATOM   6535 N  NZ  . LYS C 1 247 ? -6.8    -1.078  -10.841 1    91.48  ? 417 LYS B NZ  1 
ATOM   6536 N  N   . TYR C 1 248 ? -11.243 -0.472  -16.35  1    58.71  ? 418 TYR B N   1 
ATOM   6537 C  CA  . TYR C 1 248 ? -12.654 -0.822  -16.355 1    53.82  ? 418 TYR B CA  1 
ATOM   6538 C  C   . TYR C 1 248 ? -13.229 -0.617  -17.755 1    50.32  ? 418 TYR B C   1 
ATOM   6539 O  O   . TYR C 1 248 ? -14.376 -0.229  -17.903 1    48.99  ? 418 TYR B O   1 
ATOM   6540 C  CB  . TYR C 1 248 ? -13.406 -0.015  -15.288 1    52.05  ? 418 TYR B CB  1 
ATOM   6541 C  CG  . TYR C 1 248 ? -12.725 0.104   -13.931 1    51.13  ? 418 TYR B CG  1 
ATOM   6542 C  CD1 . TYR C 1 248 ? -12.864 -0.874  -12.941 1    49.97  ? 418 TYR B CD1 1 
ATOM   6543 C  CD2 . TYR C 1 248 ? -11.945 1.215   -13.645 1    49.84  ? 418 TYR B CD2 1 
ATOM   6544 C  CE1 . TYR C 1 248 ? -12.223 -0.753  -11.712 1    47.6   ? 418 TYR B CE1 1 
ATOM   6545 C  CE2 . TYR C 1 248 ? -11.299 1.342   -12.429 1    52.09  ? 418 TYR B CE2 1 
ATOM   6546 C  CZ  . TYR C 1 248 ? -11.44  0.366   -11.451 1    54.06  ? 418 TYR B CZ  1 
ATOM   6547 O  OH  . TYR C 1 248 ? -10.768 0.581   -10.255 1    62.93  ? 418 TYR B OH  1 
ATOM   6548 N  N   . HIS C 1 249 ? -12.415 -0.858  -18.777 1    49.85  ? 419 HIS B N   1 
ATOM   6549 C  CA  . HIS C 1 249 ? -12.856 -0.899  -20.163 1    52.59  ? 419 HIS B CA  1 
ATOM   6550 C  C   . HIS C 1 249 ? -13.454 0.428   -20.626 1    52.49  ? 419 HIS B C   1 
ATOM   6551 O  O   . HIS C 1 249 ? -14.042 0.483   -21.699 1    53.69  ? 419 HIS B O   1 
ATOM   6552 C  CB  . HIS C 1 249 ? -13.751 -2.111  -20.431 1    58.42  ? 419 HIS B CB  1 
ATOM   6553 C  CG  . HIS C 1 249 ? -13.125 -3.429  -20.071 1    72.32  ? 419 HIS B CG  1 
ATOM   6554 N  ND1 . HIS C 1 249 ? -13.242 -4.012  -18.819 1    74.07  ? 419 HIS B ND1 1 
ATOM   6555 C  CD2 . HIS C 1 249 ? -12.384 -4.282  -20.803 1    75.64  ? 419 HIS B CD2 1 
ATOM   6556 C  CE1 . HIS C 1 249 ? -12.569 -5.16   -18.798 1    73.08  ? 419 HIS B CE1 1 
ATOM   6557 N  NE2 . HIS C 1 249 ? -12.054 -5.346  -19.995 1    77.18  ? 419 HIS B NE2 1 
ATOM   6558 N  N   . GLY C 1 250 ? -13.261 1.508   -19.857 1    53.39  ? 420 GLY B N   1 
ATOM   6559 C  CA  . GLY C 1 250 ? -13.665 2.841   -20.296 1    54.83  ? 420 GLY B CA  1 
ATOM   6560 C  C   . GLY C 1 250 ? -15.187 3.012   -20.406 1    56.17  ? 420 GLY B C   1 
ATOM   6561 O  O   . GLY C 1 250 ? -15.632 3.89    -21.147 1    57.99  ? 420 GLY B O   1 
ATOM   6562 N  N   . VAL C 1 251 ? -15.957 2.221   -19.627 1    46.63  ? 421 VAL B N   1 
ATOM   6563 C  CA  . VAL C 1 251 ? -17.405 2.131   -19.698 1    44.83  ? 421 VAL B CA  1 
ATOM   6564 C  C   . VAL C 1 251 ? -18.119 3.448   -19.37  1    47.56  ? 421 VAL B C   1 
ATOM   6565 O  O   . VAL C 1 251 ? -19.241 3.666   -19.824 1    50.71  ? 421 VAL B O   1 
ATOM   6566 C  CB  . VAL C 1 251 ? -17.943 0.976   -18.846 1    41.82  ? 421 VAL B CB  1 
ATOM   6567 C  CG1 . VAL C 1 251 ? -17.477 -0.358  -19.396 1    42.19  ? 421 VAL B CG1 1 
ATOM   6568 C  CG2 . VAL C 1 251 ? -17.599 1.088   -17.368 1    38.76  ? 421 VAL B CG2 1 
ATOM   6569 N  N   . SER C 1 252 ? -17.573 4.347   -18.699 1    49.79  ? 422 SER B N   1 
ATOM   6570 C  CA  . SER C 1 252 ? -18.203 5.657   -18.418 1    49.32  ? 422 SER B CA  1 
ATOM   6571 C  C   . SER C 1 252 ? -18.303 6.447   -19.72  1    55.87  ? 422 SER B C   1 
ATOM   6572 O  O   . SER C 1 252 ? -18.892 7.535   -19.699 1    60.63  ? 422 SER B O   1 
ATOM   6573 C  CB  . SER C 1 252 ? -17.394 6.409   -17.414 1    48.77  ? 422 SER B CB  1 
ATOM   6574 O  OG  . SER C 1 252 ? -16.2   6.906   -17.994 1    51.27  ? 422 SER B OG  1 
ATOM   6575 N  N   . LEU C 1 253 ? -17.647 5.921   -20.802 1    56.54  ? 423 LEU B N   1 
ATOM   6576 C  CA  . LEU C 1 253 ? -17.72  6.615   -22.074 1    58.68  ? 423 LEU B CA  1 
ATOM   6577 C  C   . LEU C 1 253 ? -18.871 6.072   -22.917 1    59.08  ? 423 LEU B C   1 
ATOM   6578 O  O   . LEU C 1 253 ? -19.31  6.745   -23.844 1    63.1   ? 423 LEU B O   1 
ATOM   6579 C  CB  . LEU C 1 253 ? -16.363 6.528   -22.779 1    60.91  ? 423 LEU B CB  1 
ATOM   6580 C  CG  . LEU C 1 253 ? -15.197 7.248   -22.074 1    60.72  ? 423 LEU B CG  1 
ATOM   6581 C  CD1 . LEU C 1 253 ? -13.901 6.988   -22.838 1    61.64  ? 423 LEU B CD1 1 
ATOM   6582 C  CD2 . LEU C 1 253 ? -15.404 8.764   -21.899 1    57.73  ? 423 LEU B CD2 1 
ATOM   6583 N  N   . LEU C 1 254 ? -19.368 4.872   -22.585 1    56.05  ? 424 LEU B N   1 
ATOM   6584 C  CA  . LEU C 1 254 ? -20.528 4.294   -23.256 1    53.83  ? 424 LEU B CA  1 
ATOM   6585 C  C   . LEU C 1 254 ? -21.741 5.22    -23.115 1    57.37  ? 424 LEU B C   1 
ATOM   6586 O  O   . LEU C 1 254 ? -21.844 5.987   -22.151 1    61.98  ? 424 LEU B O   1 
ATOM   6587 C  CB  . LEU C 1 254 ? -20.799 2.904   -22.678 1    47.57  ? 424 LEU B CB  1 
ATOM   6588 C  CG  . LEU C 1 254 ? -19.815 1.801   -23.08  1    46.13  ? 424 LEU B CG  1 
ATOM   6589 C  CD1 . LEU C 1 254 ? -20.092 0.495   -22.349 1    40.2   ? 424 LEU B CD1 1 
ATOM   6590 C  CD2 . LEU C 1 254 ? -19.835 1.624   -24.632 1    46.44  ? 424 LEU B CD2 1 
ATOM   6591 N  N   . ASN C 1 255 ? -22.649 5.157   -24.095 1    58.98  ? 425 ASN B N   1 
ATOM   6592 C  CA  . ASN C 1 255 ? -23.85  5.977   -24.091 1    58.65  ? 425 ASN B CA  1 
ATOM   6593 C  C   . ASN C 1 255 ? -25.018 5.221   -23.461 1    57.54  ? 425 ASN B C   1 
ATOM   6594 O  O   . ASN C 1 255 ? -25.378 4.141   -23.923 1    57.37  ? 425 ASN B O   1 
ATOM   6595 C  CB  . ASN C 1 255 ? -24.247 6.401   -25.493 1    57.68  ? 425 ASN B CB  1 
ATOM   6596 C  CG  . ASN C 1 255 ? -23.47  7.603   -25.965 1    61.14  ? 425 ASN B CG  1 
ATOM   6597 O  OD1 . ASN C 1 255 ? -23.276 7.749   -27.17  1    63.53  ? 425 ASN B OD1 1 
ATOM   6598 N  ND2 . ASN C 1 255 ? -23.111 8.521   -25.075 1    61.48  ? 425 ASN B ND2 1 
ATOM   6599 N  N   . PRO C 1 256 ? -25.68  5.795   -22.428 1    54.44  ? 426 PRO B N   1 
ATOM   6600 C  CA  . PRO C 1 256 ? -26.862 5.155   -21.847 1    51.51  ? 426 PRO B CA  1 
ATOM   6601 C  C   . PRO C 1 256 ? -28.003 5.076   -22.862 1    55.11  ? 426 PRO B C   1 
ATOM   6602 O  O   . PRO C 1 256 ? -28.126 5.944   -23.73  1    57.27  ? 426 PRO B O   1 
ATOM   6603 C  CB  . PRO C 1 256 ? -27.182 6.105   -20.697 1    49.52  ? 426 PRO B CB  1 
ATOM   6604 C  CG  . PRO C 1 256 ? -26.695 7.467   -21.188 1    50.08  ? 426 PRO B CG  1 
ATOM   6605 C  CD  . PRO C 1 256 ? -25.387 7.127   -21.86  1    50.56  ? 426 PRO B CD  1 
ATOM   6606 N  N   . PRO C 1 257 ? -28.904 4.068   -22.759 1    54.95  ? 427 PRO B N   1 
ATOM   6607 C  CA  . PRO C 1 257 ? -30.059 3.973   -23.664 1    53.11  ? 427 PRO B CA  1 
ATOM   6608 C  C   . PRO C 1 257 ? -31.116 5.035   -23.38  1    56.35  ? 427 PRO B C   1 
ATOM   6609 O  O   . PRO C 1 257 ? -31.333 5.412   -22.233 1    54.16  ? 427 PRO B O   1 
ATOM   6610 C  CB  . PRO C 1 257 ? -30.616 2.574   -23.377 1    52.29  ? 427 PRO B CB  1 
ATOM   6611 C  CG  . PRO C 1 257 ? -30.212 2.312   -21.915 1    52.25  ? 427 PRO B CG  1 
ATOM   6612 C  CD  . PRO C 1 257 ? -28.874 3.009   -21.723 1    50.28  ? 427 PRO B CD  1 
ATOM   6613 N  N   . GLU C 1 258 ? -31.805 5.488   -24.432 1    65.19  ? 428 GLU B N   1 
ATOM   6614 C  CA  . GLU C 1 258 ? -32.842 6.498   -24.295 1    73.4   ? 428 GLU B CA  1 
ATOM   6615 C  C   . GLU C 1 258 ? -34.046 5.983   -23.498 1    67.82  ? 428 GLU B C   1 
ATOM   6616 O  O   . GLU C 1 258 ? -34.718 6.775   -22.847 1    66.62  ? 428 GLU B O   1 
ATOM   6617 C  CB  . GLU C 1 258 ? -33.21  7.074   -25.665 1    88.34  ? 428 GLU B CB  1 
ATOM   6618 C  CG  . GLU C 1 258 ? -32.178 8.062   -26.208 1    103.38 ? 428 GLU B CG  1 
ATOM   6619 C  CD  . GLU C 1 258 ? -31.999 9.359   -25.419 1    118.6  ? 428 GLU B CD  1 
ATOM   6620 O  OE1 . GLU C 1 258 ? -31.647 9.348   -24.204 1    110.93 ? 428 GLU B OE1 1 
ATOM   6621 O  OE2 . GLU C 1 258 ? -32.218 10.418  -26.057 1    127.26 ? 428 GLU B OE2 1 
ATOM   6622 N  N   . THR C 1 259 ? -34.317 4.669   -23.58  1    64.38  ? 429 THR B N   1 
ATOM   6623 C  CA  . THR C 1 259 ? -35.51  4.012   -23.042 1    65.95  ? 429 THR B CA  1 
ATOM   6624 C  C   . THR C 1 259 ? -35.21  2.557   -22.664 1    66.97  ? 429 THR B C   1 
ATOM   6625 O  O   . THR C 1 259 ? -34.268 1.964   -23.168 1    68.29  ? 429 THR B O   1 
ATOM   6626 C  CB  . THR C 1 259 ? -36.682 4.058   -24.028 1    68.03  ? 429 THR B CB  1 
ATOM   6627 O  OG1 . THR C 1 259 ? -36.283 3.302   -25.17  1    67.45  ? 429 THR B OG1 1 
ATOM   6628 C  CG2 . THR C 1 259 ? -37.125 5.468   -24.387 1    69.36  ? 429 THR B CG2 1 
ATOM   6629 N  N   . LEU C 1 260 ? -35.954 2.019   -21.709 1    69.8   ? 430 LEU B N   1 
ATOM   6630 C  CA  . LEU C 1 260 ? -35.649 0.655   -21.217 1    70.32  ? 430 LEU B CA  1 
ATOM   6631 C  C   . LEU C 1 260 ? -36.621 -0.319  -21.868 1    78.63  ? 430 LEU B C   1 
ATOM   6632 O  O   . LEU C 1 260 ? -36.537 -1.525  -21.569 1    74.35  ? 430 LEU B O   1 
ATOM   6633 C  CB  . LEU C 1 260 ? -35.77  0.647   -19.697 1    64.27  ? 430 LEU B CB  1 
ATOM   6634 C  CG  . LEU C 1 260 ? -34.773 1.532   -18.95  1    64.54  ? 430 LEU B CG  1 
ATOM   6635 C  CD1 . LEU C 1 260 ? -34.853 1.253   -17.462 1    64.46  ? 430 LEU B CD1 1 
ATOM   6636 C  CD2 . LEU C 1 260 ? -33.381 1.261   -19.479 1    60.12  ? 430 LEU B CD2 1 
ATOM   6637 N  N   . ASN C 1 261 ? -37.498 0.206   -22.72  1    90.96  ? 431 ASN B N   1 
ATOM   6638 C  CA  . ASN C 1 261 ? -38.496 -0.643  -23.421 1    100.6  ? 431 ASN B CA  1 
ATOM   6639 C  C   . ASN C 1 261 ? -39.16  -1.546  -22.383 1    102.31 ? 431 ASN B C   1 
ATOM   6640 O  O   . ASN C 1 261 ? -39.017 -2.785  -22.482 1    91.85  ? 431 ASN B O   1 
ATOM   6641 C  CB  . ASN C 1 261 ? -37.868 -1.394  -24.588 1    102.04 ? 431 ASN B CB  1 
ATOM   6642 C  CG  . ASN C 1 261 ? -38.062 -0.663  -25.893 1    103.85 ? 431 ASN B CG  1 
ATOM   6643 O  OD1 . ASN C 1 261 ? -38.273 0.554   -25.897 1    102.68 ? 431 ASN B OD1 1 
ATOM   6644 N  ND2 . ASN C 1 261 ? -38.003 -1.385  -27.002 1    97.15  ? 431 ASN B ND2 1 
ATOM   6645 N  N   . VAL C 1 262 ? -39.869 -0.935  -21.437 1    103.63 ? 432 VAL B N   1 
ATOM   6646 C  CA  . VAL C 1 262 ? -40.524 -1.722  -20.357 1    107.28 ? 432 VAL B CA  1 
ATOM   6647 C  C   . VAL C 1 262 ? -39.61  -2.908  -20.024 1    99.51  ? 432 VAL B C   1 
ATOM   6648 O  O   . VAL C 1 262 ? -38.825 -2.757  -19.069 1    85.49  ? 432 VAL B O   1 
ATOM   6649 C  CB  . VAL C 1 262 ? -41.934 -2.181  -20.773 1    110.32 ? 432 VAL B CB  1 
ATOM   6650 C  CG1 . VAL C 1 262 ? -42.568 -3.091  -19.728 1    104.7  ? 432 VAL B CG1 1 
ATOM   6651 C  CG2 . VAL C 1 262 ? -42.844 -0.999  -21.08  1    98.81  ? 432 VAL B CG2 1 
ATOM   6652 N  N   . SER D 2 4   ? -14.853 4.672   28.852  1    69.59  ? 0   SER C N   1 
ATOM   6653 C  CA  . SER D 2 4   ? -16.344 4.595   28.939  1    75.08  ? 0   SER C CA  1 
ATOM   6654 C  C   . SER D 2 4   ? -16.972 5.944   28.579  1    73.85  ? 0   SER C C   1 
ATOM   6655 O  O   . SER D 2 4   ? -17.742 6.084   27.618  1    69.27  ? 0   SER C O   1 
ATOM   6656 C  CB  . SER D 2 4   ? -16.79  4.147   30.325  1    73.05  ? 0   SER C CB  1 
ATOM   6657 O  OG  . SER D 2 4   ? -16.532 2.766   30.528  1    75.94  ? 0   SER C OG  1 
ATOM   6658 N  N   . MET D 2 5   ? -16.584 6.94    29.377  1    73.76  ? 1   MET C N   1 
ATOM   6659 C  CA  . MET D 2 5   ? -17.035 8.31    29.236  1    69.54  ? 1   MET C CA  1 
ATOM   6660 C  C   . MET D 2 5   ? -15.905 9.155   28.656  1    64.45  ? 1   MET C C   1 
ATOM   6661 O  O   . MET D 2 5   ? -15.985 10.379  28.655  1    65.01  ? 1   MET C O   1 
ATOM   6662 C  CB  . MET D 2 5   ? -17.462 8.863   30.604  1    67.78  ? 1   MET C CB  1 
ATOM   6663 C  CG  . MET D 2 5   ? -18.559 8.051   31.256  1    63.08  ? 1   MET C CG  1 
ATOM   6664 S  SD  . MET D 2 5   ? -20.068 7.951   30.27   1    66.51  ? 1   MET C SD  1 
ATOM   6665 C  CE  . MET D 2 5   ? -20.586 9.661   30.486  1    59.72  ? 1   MET C CE  1 
ATOM   6666 N  N   . GLU D 2 6   ? -14.865 8.488   28.16   1    61.84  ? 2   GLU C N   1 
ATOM   6667 C  CA  . GLU D 2 6   ? -13.746 9.186   27.564  1    66.61  ? 2   GLU C CA  1 
ATOM   6668 C  C   . GLU D 2 6   ? -14.142 10.082  26.391  1    61.87  ? 2   GLU C C   1 
ATOM   6669 O  O   . GLU D 2 6   ? -13.506 11.111  26.199  1    61.21  ? 2   GLU C O   1 
ATOM   6670 C  CB  . GLU D 2 6   ? -12.608 8.241   27.2    1    78.86  ? 2   GLU C CB  1 
ATOM   6671 C  CG  . GLU D 2 6   ? -11.53  8.202   28.282  1    100.2  ? 2   GLU C CG  1 
ATOM   6672 C  CD  . GLU D 2 6   ? -10.815 9.523   28.523  1    108.22 ? 2   GLU C CD  1 
ATOM   6673 O  OE1 . GLU D 2 6   ? -9.962  9.866   27.673  1    117.82 ? 2   GLU C OE1 1 
ATOM   6674 O  OE2 . GLU D 2 6   ? -11.119 10.207  29.534  1    104.38 ? 2   GLU C OE2 1 
ATOM   6675 N  N   . ASN D 2 7   ? -15.167 9.707   25.61   1    57.9   ? 3   ASN C N   1 
ATOM   6676 C  CA  . ASN D 2 7   ? -15.512 10.518  24.453  1    58.29  ? 3   ASN C CA  1 
ATOM   6677 C  C   . ASN D 2 7   ? -16.443 11.663  24.832  1    57.67  ? 3   ASN C C   1 
ATOM   6678 O  O   . ASN D 2 7   ? -16.707 12.516  23.983  1    58.64  ? 3   ASN C O   1 
ATOM   6679 C  CB  . ASN D 2 7   ? -16.112 9.741   23.287  1    58.03  ? 3   ASN C CB  1 
ATOM   6680 C  CG  . ASN D 2 7   ? -15.208 8.611   22.87   1    62.49  ? 3   ASN C CG  1 
ATOM   6681 O  OD1 . ASN D 2 7   ? -13.987 8.821   22.741  1    64     ? 3   ASN C OD1 1 
ATOM   6682 N  ND2 . ASN D 2 7   ? -15.78  7.414   22.733  1    55.86  ? 3   ASN C ND2 1 
ATOM   6683 N  N   . PHE D 2 8   ? -16.917 11.691  26.087  1    54.36  ? 4   PHE C N   1 
ATOM   6684 C  CA  . PHE D 2 8   ? -17.746 12.802  26.53   1    53.79  ? 4   PHE C CA  1 
ATOM   6685 C  C   . PHE D 2 8   ? -16.909 13.826  27.303  1    57.25  ? 4   PHE C C   1 
ATOM   6686 O  O   . PHE D 2 8   ? -16.124 13.454  28.176  1    60.73  ? 4   PHE C O   1 
ATOM   6687 C  CB  . PHE D 2 8   ? -18.982 12.283  27.262  1    49.17  ? 4   PHE C CB  1 
ATOM   6688 C  CG  . PHE D 2 8   ? -19.908 11.462  26.387  1    47.42  ? 4   PHE C CG  1 
ATOM   6689 C  CD1 . PHE D 2 8   ? -20.699 12.076  25.431  1    48.61  ? 4   PHE C CD1 1 
ATOM   6690 C  CD2 . PHE D 2 8   ? -19.984 10.081  26.52   1    47.58  ? 4   PHE C CD2 1 
ATOM   6691 C  CE1 . PHE D 2 8   ? -21.549 11.32   24.623  1    51     ? 4   PHE C CE1 1 
ATOM   6692 C  CE2 . PHE D 2 8   ? -20.824 9.333   25.713  1    48.87  ? 4   PHE C CE2 1 
ATOM   6693 C  CZ  . PHE D 2 8   ? -21.615 9.951   24.769  1    49.96  ? 4   PHE C CZ  1 
ATOM   6694 N  N   . GLN D 2 9   ? -17.072 15.11   26.931  1    58.03  ? 5   GLN C N   1 
ATOM   6695 C  CA  . GLN D 2 9   ? -16.606 16.275  27.668  1    58.95  ? 5   GLN C CA  1 
ATOM   6696 C  C   . GLN D 2 9   ? -17.803 16.996  28.295  1    60.23  ? 5   GLN C C   1 
ATOM   6697 O  O   . GLN D 2 9   ? -18.732 17.411  27.595  1    58.09  ? 5   GLN C O   1 
ATOM   6698 C  CB  . GLN D 2 9   ? -15.9   17.215  26.697  1    62.35  ? 5   GLN C CB  1 
ATOM   6699 C  CG  . GLN D 2 9   ? -15.469 18.542  27.308  1    71.67  ? 5   GLN C CG  1 
ATOM   6700 C  CD  . GLN D 2 9   ? -14.244 18.442  28.193  1    79.28  ? 5   GLN C CD  1 
ATOM   6701 O  OE1 . GLN D 2 9   ? -13.112 18.337  27.714  1    85.22  ? 5   GLN C OE1 1 
ATOM   6702 N  NE2 . GLN D 2 9   ? -14.45  18.494  29.501  1    78.56  ? 5   GLN C NE2 1 
ATOM   6703 N  N   . LYS D 2 10  ? -17.794 17.118  29.633  1    63.48  ? 6   LYS C N   1 
ATOM   6704 C  CA  . LYS D 2 10  ? -18.804 17.872  30.366  1    64.12  ? 6   LYS C CA  1 
ATOM   6705 C  C   . LYS D 2 10  ? -18.719 19.351  29.991  1    62.94  ? 6   LYS C C   1 
ATOM   6706 O  O   . LYS D 2 10  ? -17.636 19.899  29.771  1    59.37  ? 6   LYS C O   1 
ATOM   6707 C  CB  . LYS D 2 10  ? -18.654 17.674  31.879  1    71.27  ? 6   LYS C CB  1 
ATOM   6708 C  CG  . LYS D 2 10  ? -19.144 16.319  32.378  1    82.47  ? 6   LYS C CG  1 
ATOM   6709 C  CD  . LYS D 2 10  ? -18.589 15.826  33.717  1    90.73  ? 6   LYS C CD  1 
ATOM   6710 C  CE  . LYS D 2 10  ? -19.159 14.476  34.105  1    90.13  ? 6   LYS C CE  1 
ATOM   6711 N  NZ  . LYS D 2 10  ? -19.131 13.488  33.014  1    80.37  ? 6   LYS C NZ  1 
ATOM   6712 N  N   . VAL D 2 11  ? -19.884 19.999  29.931  1    59.58  ? 7   VAL C N   1 
ATOM   6713 C  CA  . VAL D 2 11  ? -19.913 21.42   29.63   1    61.6   ? 7   VAL C CA  1 
ATOM   6714 C  C   . VAL D 2 11  ? -20.432 22.194  30.853  1    62.89  ? 7   VAL C C   1 
ATOM   6715 O  O   . VAL D 2 11  ? -19.793 23.126  31.323  1    67.57  ? 7   VAL C O   1 
ATOM   6716 C  CB  . VAL D 2 11  ? -20.716 21.665  28.34   1    57.47  ? 7   VAL C CB  1 
ATOM   6717 C  CG1 . VAL D 2 11  ? -20.901 23.145  28.051  1    55.86  ? 7   VAL C CG1 1 
ATOM   6718 C  CG2 . VAL D 2 11  ? -20.045 20.973  27.161  1    58.68  ? 7   VAL C CG2 1 
ATOM   6719 N  N   . GLU D 2 12  ? -21.567 21.776  31.41   1    60.22  ? 8   GLU C N   1 
ATOM   6720 C  CA  . GLU D 2 12  ? -22.155 22.449  32.551  1    63.97  ? 8   GLU C CA  1 
ATOM   6721 C  C   . GLU D 2 12  ? -23.224 21.555  33.176  1    67.36  ? 8   GLU C C   1 
ATOM   6722 O  O   . GLU D 2 12  ? -23.834 20.742  32.489  1    61.09  ? 8   GLU C O   1 
ATOM   6723 C  CB  . GLU D 2 12  ? -22.731 23.805  32.137  1    66.51  ? 8   GLU C CB  1 
ATOM   6724 C  CG  . GLU D 2 12  ? -23.802 23.729  31.054  1    71.61  ? 8   GLU C CG  1 
ATOM   6725 C  CD  . GLU D 2 12  ? -24.371 25.046  30.555  1    79.74  ? 8   GLU C CD  1 
ATOM   6726 O  OE1 . GLU D 2 12  ? -23.571 25.777  29.938  1    80.99  ? 8   GLU C OE1 1 
ATOM   6727 O  OE2 . GLU D 2 12  ? -25.578 25.343  30.77   1    81.35  ? 8   GLU C OE2 1 
ATOM   6728 N  N   . LYS D 2 13  ? -23.44  21.712  34.486  1    74.34  ? 9   LYS C N   1 
ATOM   6729 C  CA  . LYS D 2 13  ? -24.6   21.133  35.141  1    85.48  ? 9   LYS C CA  1 
ATOM   6730 C  C   . LYS D 2 13  ? -25.853 21.806  34.568  1    81.52  ? 9   LYS C C   1 
ATOM   6731 O  O   . LYS D 2 13  ? -25.876 23.021  34.422  1    88.16  ? 9   LYS C O   1 
ATOM   6732 C  CB  . LYS D 2 13  ? -24.338 21.257  36.649  1    100.81 ? 9   LYS C CB  1 
ATOM   6733 C  CG  . LYS D 2 13  ? -25.419 20.745  37.6    1    118.1  ? 9   LYS C CG  1 
ATOM   6734 C  CD  . LYS D 2 13  ? -26.329 21.794  38.239  1    123.33 ? 9   LYS C CD  1 
ATOM   6735 C  CE  . LYS D 2 13  ? -27.151 21.252  39.366  1    131.63 ? 9   LYS C CE  1 
ATOM   6736 N  NZ  . LYS D 2 13  ? -26.347 20.554  40.37   1    147.53 ? 9   LYS C NZ  1 
ATOM   6737 N  N   . ILE D 2 14  ? -26.798 20.998  34.093  1    75.64  ? 10  ILE C N   1 
ATOM   6738 C  CA  . ILE D 2 14  ? -28.02  21.576  33.467  1    79.22  ? 10  ILE C CA  1 
ATOM   6739 C  C   . ILE D 2 14  ? -29.169 21.354  34.448  1    85.03  ? 10  ILE C C   1 
ATOM   6740 O  O   . ILE D 2 14  ? -30.326 21.649  34.099  1    88.5   ? 10  ILE C O   1 
ATOM   6741 C  CB  . ILE D 2 14  ? -28.32  20.969  32.085  1    79.57  ? 10  ILE C CB  1 
ATOM   6742 C  CG1 . ILE D 2 14  ? -28.284 19.452  32.078  1    69.52  ? 10  ILE C CG1 1 
ATOM   6743 C  CG2 . ILE D 2 14  ? -27.38  21.561  31.036  1    96.43  ? 10  ILE C CG2 1 
ATOM   6744 C  CD1 . ILE D 2 14  ? -28.56  18.851  30.714  1    63.16  ? 10  ILE C CD1 1 
ATOM   6745 N  N   . GLY D 2 15  ? -28.833 20.861  35.633  1    85.85  ? 11  GLY C N   1 
ATOM   6746 C  CA  . GLY D 2 15  ? -29.862 20.65   36.654  1    83.98  ? 11  GLY C CA  1 
ATOM   6747 C  C   . GLY D 2 15  ? -29.627 19.359  37.389  1    88.57  ? 11  GLY C C   1 
ATOM   6748 O  O   . GLY D 2 15  ? -28.601 18.707  37.133  1    91.34  ? 11  GLY C O   1 
ATOM   6749 N  N   . GLU D 2 16  ? -30.534 19.02   38.296  1    95.93  ? 12  GLU C N   1 
ATOM   6750 C  CA  . GLU D 2 16  ? -30.427 17.731  39.016  1    108.21 ? 12  GLU C CA  1 
ATOM   6751 C  C   . GLU D 2 16  ? -31.742 16.989  38.806  1    108.66 ? 12  GLU C C   1 
ATOM   6752 O  O   . GLU D 2 16  ? -32.495 17.36   37.887  1    114.75 ? 12  GLU C O   1 
ATOM   6753 C  CB  . GLU D 2 16  ? -30.148 17.899  40.508  1    104.37 ? 12  GLU C CB  1 
ATOM   6754 C  CG  . GLU D 2 16  ? -28.66  17.917  40.834  1    113.16 ? 12  GLU C CG  1 
ATOM   6755 C  CD  . GLU D 2 16  ? -28.346 17.602  42.282  1    118.61 ? 12  GLU C CD  1 
ATOM   6756 O  OE1 . GLU D 2 16  ? -28.113 18.559  43.049  1    115.56 ? 12  GLU C OE1 1 
ATOM   6757 O  OE2 . GLU D 2 16  ? -28.337 16.406  42.642  1    121.39 ? 12  GLU C OE2 1 
ATOM   6758 N  N   . GLY D 2 17  ? -32.001 15.99   39.638  1    109.98 ? 13  GLY C N   1 
ATOM   6759 C  CA  . GLY D 2 17  ? -33.212 15.187  39.446  1    115    ? 13  GLY C CA  1 
ATOM   6760 C  C   . GLY D 2 17  ? -33.235 14.02   40.395  1    123.51 ? 13  GLY C C   1 
ATOM   6761 O  O   . GLY D 2 17  ? -32.578 14.103  41.447  1    129.76 ? 13  GLY C O   1 
ATOM   6762 N  N   . THR D 2 18  ? -33.947 12.961  40.026  1    127.58 ? 14  THR C N   1 
ATOM   6763 C  CA  . THR D 2 18  ? -34.11  11.82   40.938  1    126.38 ? 14  THR C CA  1 
ATOM   6764 C  C   . THR D 2 18  ? -32.778 11.166  41.175  1    120.71 ? 14  THR C C   1 
ATOM   6765 O  O   . THR D 2 18  ? -32.415 10.98   42.354  1    116.61 ? 14  THR C O   1 
ATOM   6766 C  CB  . THR D 2 18  ? -35.096 10.846  40.297  1    125.05 ? 14  THR C CB  1 
ATOM   6767 O  OG1 . THR D 2 18  ? -35.382 9.876   41.298  1    140.58 ? 14  THR C OG1 1 
ATOM   6768 C  CG2 . THR D 2 18  ? -34.528 10.167  39.063  1    115.88 ? 14  THR C CG2 1 
ATOM   6769 N  N   . TYR D 2 19  ? -32.056 10.851  40.105  1    105.7  ? 15  TYR C N   1 
ATOM   6770 C  CA  . TYR D 2 19  ? -30.812 10.059  40.257  1    99.41  ? 15  TYR C CA  1 
ATOM   6771 C  C   . TYR D 2 19  ? -29.687 10.911  40.769  1    101.5  ? 15  TYR C C   1 
ATOM   6772 O  O   . TYR D 2 19  ? -28.786 10.393  41.457  1    97.39  ? 15  TYR C O   1 
ATOM   6773 C  CB  . TYR D 2 19  ? -30.574 9.549   38.843  1    94.16  ? 15  TYR C CB  1 
ATOM   6774 C  CG  . TYR D 2 19  ? -31.784 8.864   38.228  1    88.24  ? 15  TYR C CG  1 
ATOM   6775 C  CD1 . TYR D 2 19  ? -32.413 7.794   38.851  1    73.76  ? 15  TYR C CD1 1 
ATOM   6776 C  CD2 . TYR D 2 19  ? -32.283 9.284   37.008  1    84.52  ? 15  TYR C CD2 1 
ATOM   6777 C  CE1 . TYR D 2 19  ? -33.51  7.173   38.278  1    66.24  ? 15  TYR C CE1 1 
ATOM   6778 C  CE2 . TYR D 2 19  ? -33.375 8.67    36.424  1    76.23  ? 15  TYR C CE2 1 
ATOM   6779 C  CZ  . TYR D 2 19  ? -33.992 7.613   37.059  1    67.75  ? 15  TYR C CZ  1 
ATOM   6780 O  OH  . TYR D 2 19  ? -35.064 7.038   36.448  1    61.26  ? 15  TYR C OH  1 
ATOM   6781 N  N   . GLY D 2 20  ? -29.722 12.191  40.419  1    94.29  ? 16  GLY C N   1 
ATOM   6782 C  CA  . GLY D 2 20  ? -28.664 13.1    40.861  1    88.63  ? 16  GLY C CA  1 
ATOM   6783 C  C   . GLY D 2 20  ? -28.464 14.196  39.854  1    92.39  ? 16  GLY C C   1 
ATOM   6784 O  O   . GLY D 2 20  ? -29.476 14.727  39.377  1    98.94  ? 16  GLY C O   1 
ATOM   6785 N  N   . VAL D 2 21  ? -27.213 14.479  39.498  1    88.39  ? 17  VAL C N   1 
ATOM   6786 C  CA  . VAL D 2 21  ? -26.909 15.624  38.596  1    82     ? 17  VAL C CA  1 
ATOM   6787 C  C   . VAL D 2 21  ? -27.17  15.259  37.133  1    80.65  ? 17  VAL C C   1 
ATOM   6788 O  O   . VAL D 2 21  ? -26.946 14.092  36.761  1    69.38  ? 17  VAL C O   1 
ATOM   6789 C  CB  . VAL D 2 21  ? -25.445 16.046  38.791  1    85.18  ? 17  VAL C CB  1 
ATOM   6790 C  CG1 . VAL D 2 21  ? -25.034 17.133  37.811  1    86.69  ? 17  VAL C CG1 1 
ATOM   6791 C  CG2 . VAL D 2 21  ? -25.166 16.474  40.225  1    90.5   ? 17  VAL C CG2 1 
ATOM   6792 N  N   . VAL D 2 22  ? -27.66  16.224  36.357  1    74.2   ? 18  VAL C N   1 
ATOM   6793 C  CA  . VAL D 2 22  ? -27.828 16.008  34.897  1    64.35  ? 18  VAL C CA  1 
ATOM   6794 C  C   . VAL D 2 22  ? -26.89  17.043  34.274  1    62.2   ? 18  VAL C C   1 
ATOM   6795 O  O   . VAL D 2 22  ? -27.013 18.228  34.617  1    70.74  ? 18  VAL C O   1 
ATOM   6796 C  CB  . VAL D 2 22  ? -29.271 16.172  34.389  1    62.11  ? 18  VAL C CB  1 
ATOM   6797 C  CG1 . VAL D 2 22  ? -29.41  15.724  32.942  1    59.39  ? 18  VAL C CG1 1 
ATOM   6798 C  CG2 . VAL D 2 22  ? -30.266 15.436  35.275  1    61.35  ? 18  VAL C CG2 1 
ATOM   6799 N  N   . TYR D 2 23  ? -25.922 16.411  33.402  1    60.7   ? 19  TYR C N   1 
ATOM   6800 C  CA  . TYR D 2 23  ? -24.919 17.335  32.83   1    60.92  ? 19  TYR C CA  1 
ATOM   6801 C  C   . TYR D 2 23  ? -25.144 17.457  31.355  1    52.13  ? 19  TYR C C   1 
ATOM   6802 O  O   . TYR D 2 23  ? -25.696 16.548  30.744  1    49.59  ? 19  TYR C O   1 
ATOM   6803 C  CB  . TYR D 2 23  ? -23.465 16.906  33.036  1    72.79  ? 19  TYR C CB  1 
ATOM   6804 C  CG  . TYR D 2 23  ? -23.092 16.304  34.382  1    90.08  ? 19  TYR C CG  1 
ATOM   6805 C  CD1 . TYR D 2 23  ? -23.467 15.01   34.723  1    93.67  ? 19  TYR C CD1 1 
ATOM   6806 C  CD2 . TYR D 2 23  ? -22.33  17.021  35.293  1    98.68  ? 19  TYR C CD2 1 
ATOM   6807 C  CE1 . TYR D 2 23  ? -23.121 14.458  35.945  1    107.28 ? 19  TYR C CE1 1 
ATOM   6808 C  CE2 . TYR D 2 23  ? -21.971 16.479  36.514  1    113.47 ? 19  TYR C CE2 1 
ATOM   6809 C  CZ  . TYR D 2 23  ? -22.368 15.196  36.841  1    124.45 ? 19  TYR C CZ  1 
ATOM   6810 O  OH  . TYR D 2 23  ? -22.016 14.665  38.046  1    134.45 ? 19  TYR C OH  1 
ATOM   6811 N  N   . LYS D 2 24  ? -24.81  18.727  30.82   1    51.95  ? 20  LYS C N   1 
ATOM   6812 C  CA  . LYS D 2 24  ? -24.807 18.828  29.35   1    47.72  ? 20  LYS C CA  1 
ATOM   6813 C  C   . LYS D 2 24  ? -23.39  18.452  28.944  1    49.07  ? 20  LYS C C   1 
ATOM   6814 O  O   . LYS D 2 24  ? -22.453 18.868  29.64   1    51.37  ? 20  LYS C O   1 
ATOM   6815 C  CB  . LYS D 2 24  ? -25.096 20.239  28.846  1    46.17  ? 20  LYS C CB  1 
ATOM   6816 C  CG  . LYS D 2 24  ? -25.174 20.379  27.341  1    48.56  ? 20  LYS C CG  1 
ATOM   6817 C  CD  . LYS D 2 24  ? -25.512 21.796  26.906  1    49.04  ? 20  LYS C CD  1 
ATOM   6818 C  CE  . LYS D 2 24  ? -25.56  21.918  25.424  1    48.82  ? 20  LYS C CE  1 
ATOM   6819 N  NZ  . LYS D 2 24  ? -25.886 23.285  25.019  1    49.53  ? 20  LYS C NZ  1 
ATOM   6820 N  N   . ALA D 2 25  ? -23.252 17.662  27.89   1    46.27  ? 21  ALA C N   1 
ATOM   6821 C  CA  . ALA D 2 25  ? -21.916 17.212  27.515  1    48.77  ? 21  ALA C CA  1 
ATOM   6822 C  C   . ALA D 2 25  ? -21.782 17.201  25.996  1    46.12  ? 21  ALA C C   1 
ATOM   6823 O  O   . ALA D 2 25  ? -22.767 17.333  25.277  1    47.26  ? 21  ALA C O   1 
ATOM   6824 C  CB  . ALA D 2 25  ? -21.65  15.84   28.133  1    48.61  ? 21  ALA C CB  1 
ATOM   6825 N  N   . ARG D 2 26  ? -20.561 17.021  25.519  1    45.03  ? 22  ARG C N   1 
ATOM   6826 C  CA  . ARG D 2 26  ? -20.313 16.991  24.092  1    48.55  ? 22  ARG C CA  1 
ATOM   6827 C  C   . ARG D 2 26  ? -19.531 15.719  23.752  1    48.7   ? 22  ARG C C   1 
ATOM   6828 O  O   . ARG D 2 26  ? -18.517 15.409  24.394  1    50.47  ? 22  ARG C O   1 
ATOM   6829 C  CB  . ARG D 2 26  ? -19.483 18.233  23.742  1    55.27  ? 22  ARG C CB  1 
ATOM   6830 C  CG  . ARG D 2 26  ? -19.828 18.914  22.427  1    68.49  ? 22  ARG C CG  1 
ATOM   6831 C  CD  . ARG D 2 26  ? -18.902 20.107  22.169  1    72.63  ? 22  ARG C CD  1 
ATOM   6832 N  NE  . ARG D 2 26  ? -17.518 19.633  22.012  1    81.65  ? 22  ARG C NE  1 
ATOM   6833 C  CZ  . ARG D 2 26  ? -16.538 19.832  22.903  1    85.65  ? 22  ARG C CZ  1 
ATOM   6834 N  NH1 . ARG D 2 26  ? -16.816 20.459  24.035  1    90.16  ? 22  ARG C NH1 1 
ATOM   6835 N  NH2 . ARG D 2 26  ? -15.302 19.411  22.677  1    74.13  ? 22  ARG C NH2 1 
ATOM   6836 N  N   . ASN D 2 27  ? -19.984 14.993  22.717  1    44.69  ? 23  ASN C N   1 
ATOM   6837 C  CA  . ASN D 2 27  ? -19.193 13.918  22.132  1    42.98  ? 23  ASN C CA  1 
ATOM   6838 C  C   . ASN D 2 27  ? -17.989 14.52   21.402  1    44.95  ? 23  ASN C C   1 
ATOM   6839 O  O   . ASN D 2 27  ? -18.132 15.185  20.375  1    44.4   ? 23  ASN C O   1 
ATOM   6840 C  CB  . ASN D 2 27  ? -20.052 13.07   21.196  1    41.28  ? 23  ASN C CB  1 
ATOM   6841 C  CG  . ASN D 2 27  ? -19.365 11.797  20.729  1    43.16  ? 23  ASN C CG  1 
ATOM   6842 O  OD1 . ASN D 2 27  ? -18.201 11.822  20.287  1    42.87  ? 23  ASN C OD1 1 
ATOM   6843 N  ND2 . ASN D 2 27  ? -20.08  10.672  20.822  1    40.59  ? 23  ASN C ND2 1 
ATOM   6844 N  N   . LYS D 2 28  ? -16.789 14.24   21.897  1    47.5   ? 24  LYS C N   1 
ATOM   6845 C  CA  . LYS D 2 28  ? -15.585 14.868  21.376  1    52.03  ? 24  LYS C CA  1 
ATOM   6846 C  C   . LYS D 2 28  ? -15.292 14.432  19.946  1    51.81  ? 24  LYS C C   1 
ATOM   6847 O  O   . LYS D 2 28  ? -14.589 15.152  19.227  1    52.97  ? 24  LYS C O   1 
ATOM   6848 C  CB  . LYS D 2 28  ? -14.368 14.543  22.245  1    58.38  ? 24  LYS C CB  1 
ATOM   6849 C  CG  . LYS D 2 28  ? -14.199 15.504  23.405  1    63.69  ? 24  LYS C CG  1 
ATOM   6850 C  CD  . LYS D 2 28  ? -12.95  15.225  24.227  1    73.62  ? 24  LYS C CD  1 
ATOM   6851 C  CE  . LYS D 2 28  ? -13.228 14.06   25.128  1    75.27  ? 24  LYS C CE  1 
ATOM   6852 N  NZ  . LYS D 2 28  ? -12.257 14.028  26.222  1    77.12  ? 24  LYS C NZ  1 
ATOM   6853 N  N   . LEU D 2 29  ? -15.816 13.257  19.557  1    49.76  ? 25  LEU C N   1 
ATOM   6854 C  CA  . LEU D 2 29  ? -15.553 12.663  18.251  1    48.97  ? 25  LEU C CA  1 
ATOM   6855 C  C   . LEU D 2 29  ? -16.645 13.037  17.244  1    50.73  ? 25  LEU C C   1 
ATOM   6856 O  O   . LEU D 2 29  ? -16.341 13.247  16.075  1    55.86  ? 25  LEU C O   1 
ATOM   6857 C  CB  . LEU D 2 29  ? -15.416 11.153  18.402  1    44.45  ? 25  LEU C CB  1 
ATOM   6858 C  CG  . LEU D 2 29  ? -14.095 10.673  18.989  1    44.03  ? 25  LEU C CG  1 
ATOM   6859 C  CD1 . LEU D 2 29  ? -14.136 9.184   19.093  1    42.81  ? 25  LEU C CD1 1 
ATOM   6860 C  CD2 . LEU D 2 29  ? -12.946 11.101  18.124  1    45.61  ? 25  LEU C CD2 1 
ATOM   6861 N  N   . THR D 2 30  ? -17.907 13.115  17.678  1    47.04  ? 26  THR C N   1 
ATOM   6862 C  CA  . THR D 2 30  ? -18.967 13.337  16.714  1    47.93  ? 26  THR C CA  1 
ATOM   6863 C  C   . THR D 2 30  ? -19.509 14.769  16.768  1    51.38  ? 26  THR C C   1 
ATOM   6864 O  O   . THR D 2 30  ? -20.201 15.182  15.839  1    53.66  ? 26  THR C O   1 
ATOM   6865 C  CB  . THR D 2 30  ? -20.083 12.302  16.845  1    44.92  ? 26  THR C CB  1 
ATOM   6866 O  OG1 . THR D 2 30  ? -20.794 12.513  18.06   1    43.86  ? 26  THR C OG1 1 
ATOM   6867 C  CG2 . THR D 2 30  ? -19.572 10.875  16.755  1    44.54  ? 26  THR C CG2 1 
ATOM   6868 N  N   . GLY D 2 31  ? -19.242 15.516  17.85   1    50.9   ? 27  GLY C N   1 
ATOM   6869 C  CA  . GLY D 2 31  ? -19.765 16.867  17.998  1    51.73  ? 27  GLY C CA  1 
ATOM   6870 C  C   . GLY D 2 31  ? -21.167 16.917  18.621  1    56.11  ? 27  GLY C C   1 
ATOM   6871 O  O   . GLY D 2 31  ? -21.664 18.003  18.942  1    60.79  ? 27  GLY C O   1 
ATOM   6872 N  N   . GLU D 2 32  ? -21.813 15.749  18.794  1    52.26  ? 28  GLU C N   1 
ATOM   6873 C  CA  . GLU D 2 32  ? -23.149 15.7    19.365  1    47.27  ? 28  GLU C CA  1 
ATOM   6874 C  C   . GLU D 2 32  ? -23.144 16.282  20.785  1    47.25  ? 28  GLU C C   1 
ATOM   6875 O  O   . GLU D 2 32  ? -22.274 15.971  21.597  1    45.1   ? 28  GLU C O   1 
ATOM   6876 C  CB  . GLU D 2 32  ? -23.685 14.272  19.365  1    43.71  ? 28  GLU C CB  1 
ATOM   6877 C  CG  . GLU D 2 32  ? -25.182 14.223  19.657  1    42.44  ? 28  GLU C CG  1 
ATOM   6878 C  CD  . GLU D 2 32  ? -25.811 12.832  19.638  1    47.25  ? 28  GLU C CD  1 
ATOM   6879 O  OE1 . GLU D 2 32  ? -25.133 11.778  19.874  1    45.6   ? 28  GLU C OE1 1 
ATOM   6880 O  OE2 . GLU D 2 32  ? -27.047 12.828  19.383  1    50.37  ? 28  GLU C OE2 1 
ATOM   6881 N  N   . VAL D 2 33  ? -24.133 17.138  21.068  1    45.15  ? 29  VAL C N   1 
ATOM   6882 C  CA  . VAL D 2 33  ? -24.396 17.628  22.414  1    42.76  ? 29  VAL C CA  1 
ATOM   6883 C  C   . VAL D 2 33  ? -25.487 16.765  23.05   1    40.12  ? 29  VAL C C   1 
ATOM   6884 O  O   . VAL D 2 33  ? -26.498 16.471  22.411  1    39.13  ? 29  VAL C O   1 
ATOM   6885 C  CB  . VAL D 2 33  ? -24.801 19.117  22.343  1    43.29  ? 29  VAL C CB  1 
ATOM   6886 C  CG1 . VAL D 2 33  ? -25.223 19.646  23.714  1    40.8   ? 29  VAL C CG1 1 
ATOM   6887 C  CG2 . VAL D 2 33  ? -23.699 19.984  21.707  1    42.29  ? 29  VAL C CG2 1 
ATOM   6888 N  N   . VAL D 2 34  ? -25.278 16.368  24.31   1    37.59  ? 30  VAL C N   1 
ATOM   6889 C  CA  . VAL D 2 34  ? -26.148 15.412  24.985  1    36.27  ? 30  VAL C CA  1 
ATOM   6890 C  C   . VAL D 2 34  ? -26.438 15.902  26.411  1    39.77  ? 30  VAL C C   1 
ATOM   6891 O  O   . VAL D 2 34  ? -25.733 16.77   26.953  1    42.99  ? 30  VAL C O   1 
ATOM   6892 C  CB  . VAL D 2 34  ? -25.51  13.998  25.02   1    34.64  ? 30  VAL C CB  1 
ATOM   6893 C  CG1 . VAL D 2 34  ? -25.25  13.424  23.637  1    33.29  ? 30  VAL C CG1 1 
ATOM   6894 C  CG2 . VAL D 2 34  ? -24.235 13.948  25.865  1    34.42  ? 30  VAL C CG2 1 
ATOM   6895 N  N   . ALA D 2 35  ? -27.471 15.317  27.033  1    39.16  ? 31  ALA C N   1 
ATOM   6896 C  CA  . ALA D 2 35  ? -27.616 15.379  28.479  1    40.65  ? 31  ALA C CA  1 
ATOM   6897 C  C   . ALA D 2 35  ? -27.192 14.035  29.063  1    42.03  ? 31  ALA C C   1 
ATOM   6898 O  O   . ALA D 2 35  ? -27.683 13.001  28.609  1    43.51  ? 31  ALA C O   1 
ATOM   6899 C  CB  . ALA D 2 35  ? -29.063 15.684  28.825  1    37.78  ? 31  ALA C CB  1 
ATOM   6900 N  N   . LEU D 2 36  ? -26.291 14.058  30.053  1    44.94  ? 32  LEU C N   1 
ATOM   6901 C  CA  . LEU D 2 36  ? -25.849 12.87   30.782  1    44.9   ? 32  LEU C CA  1 
ATOM   6902 C  C   . LEU D 2 36  ? -26.518 12.798  32.148  1    46.76  ? 32  LEU C C   1 
ATOM   6903 O  O   . LEU D 2 36  ? -26.286 13.67   32.989  1    49.27  ? 32  LEU C O   1 
ATOM   6904 C  CB  . LEU D 2 36  ? -24.351 12.946  31.017  1    43.36  ? 32  LEU C CB  1 
ATOM   6905 C  CG  . LEU D 2 36  ? -23.494 12.805  29.77   1    46.97  ? 32  LEU C CG  1 
ATOM   6906 C  CD1 . LEU D 2 36  ? -22.021 12.709  30.167  1    47.45  ? 32  LEU C CD1 1 
ATOM   6907 C  CD2 . LEU D 2 36  ? -23.964 11.612  28.965  1    46.36  ? 32  LEU C CD2 1 
ATOM   6908 N  N   . LYS D 2 37  ? -27.298 11.738  32.378  1    45.64  ? 33  LYS C N   1 
ATOM   6909 C  CA  . LYS D 2 37  ? -27.865 11.467  33.689  1    46.01  ? 33  LYS C CA  1 
ATOM   6910 C  C   . LYS D 2 37  ? -26.954 10.459  34.384  1    46.61  ? 33  LYS C C   1 
ATOM   6911 O  O   . LYS D 2 37  ? -26.764 9.35    33.914  1    52.38  ? 33  LYS C O   1 
ATOM   6912 C  CB  . LYS D 2 37  ? -29.296 10.958  33.474  1    48.95  ? 33  LYS C CB  1 
ATOM   6913 C  CG  . LYS D 2 37  ? -30.39  11.449  34.404  1    53.38  ? 33  LYS C CG  1 
ATOM   6914 C  CD  . LYS D 2 37  ? -31.781 10.901  34.066  1    60.98  ? 33  LYS C CD  1 
ATOM   6915 C  CE  . LYS D 2 37  ? -32.986 11.6    34.661  1    68.02  ? 33  LYS C CE  1 
ATOM   6916 N  NZ  . LYS D 2 37  ? -34.287 11.157  34.138  1    62.94  ? 33  LYS C NZ  1 
ATOM   6917 N  N   . LYS D 2 38  ? -26.334 10.848  35.487  1    49.14  ? 34  LYS C N   1 
ATOM   6918 C  CA  . LYS D 2 38  ? -25.522 9.903   36.236  1    56.39  ? 34  LYS C CA  1 
ATOM   6919 C  C   . LYS D 2 38  ? -26.364 9.306   37.363  1    58.59  ? 34  LYS C C   1 
ATOM   6920 O  O   . LYS D 2 38  ? -26.934 10.048  38.15   1    68.91  ? 34  LYS C O   1 
ATOM   6921 C  CB  . LYS D 2 38  ? -24.252 10.578  36.767  1    54.87  ? 34  LYS C CB  1 
ATOM   6922 C  CG  . LYS D 2 38  ? -23.573 9.766   37.848  1    59.31  ? 34  LYS C CG  1 
ATOM   6923 C  CD  . LYS D 2 38  ? -22.201 10.303  38.254  1    64.78  ? 34  LYS C CD  1 
ATOM   6924 C  CE  . LYS D 2 38  ? -22.209 11.502  39.123  1    68.31  ? 34  LYS C CE  1 
ATOM   6925 N  NZ  . LYS D 2 38  ? -20.864 11.664  39.675  1    74.94  ? 34  LYS C NZ  1 
ATOM   6926 N  N   . ILE D 2 39  ? -26.453 7.971   37.428  1    58.23  ? 35  ILE C N   1 
ATOM   6927 C  CA  . ILE D 2 39  ? -27.207 7.276   38.47   1    54.73  ? 35  ILE C CA  1 
ATOM   6928 C  C   . ILE D 2 39  ? -26.238 6.469   39.332  1    59.42  ? 35  ILE C C   1 
ATOM   6929 O  O   . ILE D 2 39  ? -25.563 5.584   38.815  1    58.45  ? 35  ILE C O   1 
ATOM   6930 C  CB  . ILE D 2 39  ? -28.28  6.359   37.855  1    51.03  ? 35  ILE C CB  1 
ATOM   6931 C  CG1 . ILE D 2 39  ? -29.225 7.152   36.981  1    52.28  ? 35  ILE C CG1 1 
ATOM   6932 C  CG2 . ILE D 2 39  ? -29.025 5.586   38.932  1    46.1   ? 35  ILE C CG2 1 
ATOM   6933 C  CD1 . ILE D 2 39  ? -30.203 6.315   36.194  1    51.14  ? 35  ILE C CD1 1 
ATOM   6934 N  N   . ARG D 2 40  ? -26.168 6.762   40.627  1    64.87  ? 36  ARG C N   1 
ATOM   6935 C  CA  . ARG D 2 40  ? -25.293 5.974   41.524  1    66.72  ? 36  ARG C CA  1 
ATOM   6936 C  C   . ARG D 2 40  ? -25.877 4.574   41.698  1    68.51  ? 36  ARG C C   1 
ATOM   6937 O  O   . ARG D 2 40  ? -27.088 4.465   41.955  1    69.69  ? 36  ARG C O   1 
ATOM   6938 C  CB  . ARG D 2 40  ? -25.178 6.606   42.91   1    77.44  ? 36  ARG C CB  1 
ATOM   6939 C  CG  . ARG D 2 40  ? -24.048 6.047   43.762  1    94.27  ? 36  ARG C CG  1 
ATOM   6940 C  CD  . ARG D 2 40  ? -22.756 5.874   42.979  1    102.92 ? 36  ARG C CD  1 
ATOM   6941 N  NE  . ARG D 2 40  ? -21.654 5.417   43.832  1    120.64 ? 36  ARG C NE  1 
ATOM   6942 C  CZ  . ARG D 2 40  ? -21.096 4.213   43.779  1    126.31 ? 36  ARG C CZ  1 
ATOM   6943 N  NH1 . ARG D 2 40  ? -19.852 4.043   44.188  1    126.54 ? 36  ARG C NH1 1 
ATOM   6944 N  NH2 . ARG D 2 40  ? -21.781 3.182   43.32   1    119.71 ? 36  ARG C NH2 1 
ATOM   6945 N  N   . LEU D 2 41  ? -25.039 3.553   41.561  1    63.25  ? 37  LEU C N   1 
ATOM   6946 C  CA  . LEU D 2 41  ? -25.514 2.174   41.81   1    60.8   ? 37  LEU C CA  1 
ATOM   6947 C  C   . LEU D 2 41  ? -25.142 1.795   43.249  1    66.25  ? 37  LEU C C   1 
ATOM   6948 O  O   . LEU D 2 41  ? -23.981 2.001   43.634  1    64.73  ? 37  LEU C O   1 
ATOM   6949 C  CB  . LEU D 2 41  ? -24.953 1.224   40.757  1    57.51  ? 37  LEU C CB  1 
ATOM   6950 C  CG  . LEU D 2 41  ? -25.364 1.518   39.313  1    53.04  ? 37  LEU C CG  1 
ATOM   6951 C  CD1 . LEU D 2 41  ? -24.881 0.416   38.397  1    50.3   ? 37  LEU C CD1 1 
ATOM   6952 C  CD2 . LEU D 2 41  ? -26.867 1.675   39.221  1    53.3   ? 37  LEU C CD2 1 
ATOM   6953 N  N   . ASP D 2 42  ? -26.101 1.296   44.015  1    65.75  ? 38  ASP C N   1 
ATOM   6954 C  CA  . ASP D 2 42  ? -25.929 0.948   45.413  1    69.8   ? 38  ASP C CA  1 
ATOM   6955 C  C   . ASP D 2 42  ? -25.363 -0.468  45.514  1    63.56  ? 38  ASP C C   1 
ATOM   6956 O  O   . ASP D 2 42  ? -26.085 -1.405  45.853  1    63.33  ? 38  ASP C O   1 
ATOM   6957 C  CB  . ASP D 2 42  ? -27.233 1.185   46.164  1    76.21  ? 38  ASP C CB  1 
ATOM   6958 C  CG  . ASP D 2 42  ? -27.62  2.646   46.324  1    78.78  ? 38  ASP C CG  1 
ATOM   6959 O  OD1 . ASP D 2 42  ? -26.822 3.394   46.93   1    85.04  ? 38  ASP C OD1 1 
ATOM   6960 O  OD2 . ASP D 2 42  ? -28.709 3.018   45.843  1    77.12  ? 38  ASP C OD2 1 
ATOM   6961 N  N   . THR D 2 43  ? -24.068 -0.611  45.241  1    57.74  ? 39  THR C N   1 
ATOM   6962 C  CA  . THR D 2 43  ? -23.505 -1.911  44.918  1    58.09  ? 39  THR C CA  1 
ATOM   6963 C  C   . THR D 2 43  ? -23.472 -2.852  46.125  1    60.08  ? 39  THR C C   1 
ATOM   6964 O  O   . THR D 2 43  ? -23.277 -4.054  45.953  1    62.53  ? 39  THR C O   1 
ATOM   6965 C  CB  . THR D 2 43  ? -22.126 -1.736  44.269  1    59.23  ? 39  THR C CB  1 
ATOM   6966 O  OG1 . THR D 2 43  ? -21.183 -1.244  45.221  1    59.11  ? 39  THR C OG1 1 
ATOM   6967 C  CG2 . THR D 2 43  ? -22.164 -0.83   43.044  1    57.22  ? 39  THR C CG2 1 
ATOM   6968 N  N   . GLU D 2 44  ? -23.61  -2.323  47.352  1    59.66  ? 40  GLU C N   1 
ATOM   6969 C  CA  . GLU D 2 44  ? -23.599 -3.21   48.504  1    60.35  ? 40  GLU C CA  1 
ATOM   6970 C  C   . GLU D 2 44  ? -24.974 -3.252  49.165  1    58.48  ? 40  GLU C C   1 
ATOM   6971 O  O   . GLU D 2 44  ? -25.192 -4.022  50.09   1    61.4   ? 40  GLU C O   1 
ATOM   6972 C  CB  . GLU D 2 44  ? -22.556 -2.848  49.559  1    65.05  ? 40  GLU C CB  1 
ATOM   6973 C  CG  . GLU D 2 44  ? -21.101 -2.944  49.096  1    68.15  ? 40  GLU C CG  1 
ATOM   6974 C  CD  . GLU D 2 44  ? -20.691 -1.905  48.059  1    66.67  ? 40  GLU C CD  1 
ATOM   6975 O  OE1 . GLU D 2 44  ? -20.072 -2.343  47.064  1    66.74  ? 40  GLU C OE1 1 
ATOM   6976 O  OE2 . GLU D 2 44  ? -21.015 -0.693  48.202  1    65.06  ? 40  GLU C OE2 1 
ATOM   6977 N  N   . THR D 2 45  ? -25.909 -2.427  48.712  1    54.85  ? 41  THR C N   1 
ATOM   6978 C  CA  . THR D 2 45  ? -27.13  -2.284  49.482  1    55.85  ? 41  THR C CA  1 
ATOM   6979 C  C   . THR D 2 45  ? -28.346 -2.672  48.654  1    54.55  ? 41  THR C C   1 
ATOM   6980 O  O   . THR D 2 45  ? -28.805 -3.797  48.789  1    57.06  ? 41  THR C O   1 
ATOM   6981 C  CB  . THR D 2 45  ? -27.231 -0.943  50.218  1    55.43  ? 41  THR C CB  1 
ATOM   6982 O  OG1 . THR D 2 45  ? -27.066 0.172   49.348  1    53.17  ? 41  THR C OG1 1 
ATOM   6983 C  CG2 . THR D 2 45  ? -26.189 -0.85   51.319  1    57.94  ? 41  THR C CG2 1 
ATOM   6984 N  N   . GLU D 2 46  ? -28.819 -1.771  47.792  1    52.81  ? 42  GLU C N   1 
ATOM   6985 C  CA  . GLU D 2 46  ? -30.091 -1.962  47.12   1    53.74  ? 42  GLU C CA  1 
ATOM   6986 C  C   . GLU D 2 46  ? -29.975 -2.19   45.605  1    50.49  ? 42  GLU C C   1 
ATOM   6987 O  O   . GLU D 2 46  ? -30.975 -2.506  44.983  1    48.39  ? 42  GLU C O   1 
ATOM   6988 C  CB  . GLU D 2 46  ? -31.109 -0.904  47.565  1    56.3   ? 42  GLU C CB  1 
ATOM   6989 C  CG  . GLU D 2 46  ? -31.548 -1.11   49.019  1    65.48  ? 42  GLU C CG  1 
ATOM   6990 C  CD  . GLU D 2 46  ? -32.06  -2.457  49.561  1    71.43  ? 42  GLU C CD  1 
ATOM   6991 O  OE1 . GLU D 2 46  ? -33.09  -3.016  49.092  1    70.6   ? 42  GLU C OE1 1 
ATOM   6992 O  OE2 . GLU D 2 46  ? -31.417 -2.959  50.518  1    79.76  ? 42  GLU C OE2 1 
ATOM   6993 N  N   . GLY D 2 47  ? -28.789 -2.05   44.999  1    50.12  ? 43  GLY C N   1 
ATOM   6994 C  CA  . GLY D 2 47  ? -28.615 -2.336  43.579  1    46.84  ? 43  GLY C CA  1 
ATOM   6995 C  C   . GLY D 2 47  ? -29.186 -1.238  42.689  1    46.61  ? 43  GLY C C   1 
ATOM   6996 O  O   . GLY D 2 47  ? -29.192 -0.072  43.062  1    53.76  ? 43  GLY C O   1 
ATOM   6997 N  N   . VAL D 2 48  ? -29.674 -1.597  41.498  1    43.21  ? 44  VAL C N   1 
ATOM   6998 C  CA  . VAL D 2 48  ? -30.111 -0.583  40.559  1    39.39  ? 44  VAL C CA  1 
ATOM   6999 C  C   . VAL D 2 48  ? -31.5   -0.105  40.963  1    40.43  ? 44  VAL C C   1 
ATOM   7000 O  O   . VAL D 2 48  ? -32.397 -0.92   41.134  1    40.23  ? 44  VAL C O   1 
ATOM   7001 C  CB  . VAL D 2 48  ? -30.121 -1.133  39.122  1    35.44  ? 44  VAL C CB  1 
ATOM   7002 C  CG1 . VAL D 2 48  ? -30.633 -0.108  38.135  1    31.59  ? 44  VAL C CG1 1 
ATOM   7003 C  CG2 . VAL D 2 48  ? -28.743 -1.611  38.709  1    35.47  ? 44  VAL C CG2 1 
ATOM   7004 N  N   . PRO D 2 49  ? -31.721 1.228   41.112  1    42.06  ? 45  PRO C N   1 
ATOM   7005 C  CA  . PRO D 2 49  ? -33.033 1.776   41.508  1    40.25  ? 45  PRO C CA  1 
ATOM   7006 C  C   . PRO D 2 49  ? -34.2   1.397   40.605  1    41.48  ? 45  PRO C C   1 
ATOM   7007 O  O   . PRO D 2 49  ? -34.079 1.47    39.379  1    42.35  ? 45  PRO C O   1 
ATOM   7008 C  CB  . PRO D 2 49  ? -32.829 3.285   41.457  1    37.92  ? 45  PRO C CB  1 
ATOM   7009 C  CG  . PRO D 2 49  ? -31.337 3.518   41.467  1    38.43  ? 45  PRO C CG  1 
ATOM   7010 C  CD  . PRO D 2 49  ? -30.685 2.264   40.942  1    40.47  ? 45  PRO C CD  1 
ATOM   7011 N  N   . SER D 2 50  ? -35.36  1.078   41.198  1    44.18  ? 46  SER C N   1 
ATOM   7012 C  CA  . SER D 2 50  ? -36.53  0.761   40.378  1    47.33  ? 46  SER C CA  1 
ATOM   7013 C  C   . SER D 2 50  ? -36.836 1.888   39.399  1    44.7   ? 46  SER C C   1 
ATOM   7014 O  O   . SER D 2 50  ? -37.26  1.637   38.269  1    44.73  ? 46  SER C O   1 
ATOM   7015 C  CB  . SER D 2 50  ? -37.761 0.363   41.168  1    50.57  ? 46  SER C CB  1 
ATOM   7016 O  OG  . SER D 2 50  ? -38.223 1.434   41.975  1    64.18  ? 46  SER C OG  1 
ATOM   7017 N  N   . THR D 2 51  ? -36.632 3.127   39.854  1    46.96  ? 47  THR C N   1 
ATOM   7018 C  CA  . THR D 2 51  ? -36.918 4.323   39.069  1    44.5   ? 47  THR C CA  1 
ATOM   7019 C  C   . THR D 2 51  ? -36.134 4.251   37.768  1    41.28  ? 47  THR C C   1 
ATOM   7020 O  O   . THR D 2 51  ? -36.676 4.609   36.736  1    40.97  ? 47  THR C O   1 
ATOM   7021 C  CB  . THR D 2 51  ? -36.473 5.574   39.815  1    47.11  ? 47  THR C CB  1 
ATOM   7022 O  OG1 . THR D 2 51  ? -36.965 5.493   41.142  1    59.24  ? 47  THR C OG1 1 
ATOM   7023 C  CG2 . THR D 2 51  ? -36.975 6.82    39.129  1    46.25  ? 47  THR C CG2 1 
ATOM   7024 N  N   . ALA D 2 52  ? -34.867 3.804   37.839  1    37.18  ? 48  ALA C N   1 
ATOM   7025 C  CA  . ALA D 2 52  ? -34.029 3.728   36.652  1    34.93  ? 48  ALA C CA  1 
ATOM   7026 C  C   . ALA D 2 52  ? -34.437 2.532   35.785  1    35.93  ? 48  ALA C C   1 
ATOM   7027 O  O   . ALA D 2 52  ? -34.488 2.649   34.571  1    35.67  ? 48  ALA C O   1 
ATOM   7028 C  CB  . ALA D 2 52  ? -32.565 3.692   37.026  1    32.65  ? 48  ALA C CB  1 
ATOM   7029 N  N   . ILE D 2 53  ? -34.734 1.377   36.395  1    36.98  ? 49  ILE C N   1 
ATOM   7030 C  CA  . ILE D 2 53  ? -35.148 0.205   35.641  1    36.33  ? 49  ILE C CA  1 
ATOM   7031 C  C   . ILE D 2 53  ? -36.399 0.511   34.805  1    40.64  ? 49  ILE C C   1 
ATOM   7032 O  O   . ILE D 2 53  ? -36.498 0.119   33.637  1    40.88  ? 49  ILE C O   1 
ATOM   7033 C  CB  . ILE D 2 53  ? -35.353 -0.96   36.611  1    34.87  ? 49  ILE C CB  1 
ATOM   7034 C  CG1 . ILE D 2 53  ? -34.018 -1.47   37.073  1    33.94  ? 49  ILE C CG1 1 
ATOM   7035 C  CG2 . ILE D 2 53  ? -36.21  -2.067  35.978  1    34.74  ? 49  ILE C CG2 1 
ATOM   7036 C  CD1 . ILE D 2 53  ? -34.107 -2.291  38.333  1    37.09  ? 49  ILE C CD1 1 
ATOM   7037 N  N   . ARG D 2 54  ? -37.341 1.251   35.398  1    40.92  ? 50  ARG C N   1 
ATOM   7038 C  CA  . ARG D 2 54  ? -38.541 1.649   34.69   1    41.31  ? 50  ARG C CA  1 
ATOM   7039 C  C   . ARG D 2 54  ? -38.238 2.668   33.592  1    44.51  ? 50  ARG C C   1 
ATOM   7040 O  O   . ARG D 2 54  ? -38.741 2.513   32.484  1    46.7   ? 50  ARG C O   1 
ATOM   7041 C  CB  . ARG D 2 54  ? -39.573 2.21    35.672  1    43.51  ? 50  ARG C CB  1 
ATOM   7042 C  CG  . ARG D 2 54  ? -40.203 1.121   36.53   1    45.98  ? 50  ARG C CG  1 
ATOM   7043 C  CD  . ARG D 2 54  ? -41.555 1.561   37.029  1    42.88  ? 50  ARG C CD  1 
ATOM   7044 N  NE  . ARG D 2 54  ? -42.159 0.535   37.874  1    42.56  ? 50  ARG C NE  1 
ATOM   7045 C  CZ  . ARG D 2 54  ? -42.895 0.784   38.945  1    42.22  ? 50  ARG C CZ  1 
ATOM   7046 N  NH1 . ARG D 2 54  ? -43.18  2.012   39.347  1    39.16  ? 50  ARG C NH1 1 
ATOM   7047 N  NH2 . ARG D 2 54  ? -43.381 -0.235  39.605  1    46     ? 50  ARG C NH2 1 
ATOM   7048 N  N   . GLU D 2 55  ? -37.451 3.715   33.889  1    41.81  ? 51  GLU C N   1 
ATOM   7049 C  CA  . GLU D 2 55  ? -37.184 4.732   32.887  1    41.64  ? 51  GLU C CA  1 
ATOM   7050 C  C   . GLU D 2 55  ? -36.466 4.14    31.67   1    40.74  ? 51  GLU C C   1 
ATOM   7051 O  O   . GLU D 2 55  ? -36.87  4.388   30.542  1    42.3   ? 51  GLU C O   1 
ATOM   7052 C  CB  . GLU D 2 55  ? -36.457 5.949   33.46   1    44.42  ? 51  GLU C CB  1 
ATOM   7053 C  CG  . GLU D 2 55  ? -36.024 6.92    32.367  1    46.93  ? 51  GLU C CG  1 
ATOM   7054 C  CD  . GLU D 2 55  ? -35.68  8.316   32.836  1    49.2   ? 51  GLU C CD  1 
ATOM   7055 O  OE1 . GLU D 2 55  ? -35.195 8.393   33.968  1    41.29  ? 51  GLU C OE1 1 
ATOM   7056 O  OE2 . GLU D 2 55  ? -35.898 9.293   32.056  1    55.66  ? 51  GLU C OE2 1 
ATOM   7057 N  N   . ILE D 2 56  ? -35.404 3.364   31.892  1    40.78  ? 52  ILE C N   1 
ATOM   7058 C  CA  . ILE D 2 56  ? -34.602 2.81    30.808  1    39.54  ? 52  ILE C CA  1 
ATOM   7059 C  C   . ILE D 2 56  ? -35.458 1.858   29.966  1    39.79  ? 52  ILE C C   1 
ATOM   7060 O  O   . ILE D 2 56  ? -35.569 2.055   28.76   1    40.61  ? 52  ILE C O   1 
ATOM   7061 C  CB  . ILE D 2 56  ? -33.283 2.182   31.317  1    37.99  ? 52  ILE C CB  1 
ATOM   7062 C  CG1 . ILE D 2 56  ? -32.418 3.21    32.052  1    36.79  ? 52  ILE C CG1 1 
ATOM   7063 C  CG2 . ILE D 2 56  ? -32.511 1.524   30.171  1    37.14  ? 52  ILE C CG2 1 
ATOM   7064 C  CD1 . ILE D 2 56  ? -31.362 2.628   32.987  1    37.1   ? 52  ILE C CD1 1 
ATOM   7065 N  N   . SER D 2 57  ? -36.098 0.863   30.596  1    42.59  ? 53  SER C N   1 
ATOM   7066 C  CA  . SER D 2 57  ? -36.89  -0.145  29.882  1    43.65  ? 53  SER C CA  1 
ATOM   7067 C  C   . SER D 2 57  ? -38.024 0.482   29.061  1    43.6   ? 53  SER C C   1 
ATOM   7068 O  O   . SER D 2 57  ? -38.246 0.076   27.925  1    47.74  ? 53  SER C O   1 
ATOM   7069 C  CB  . SER D 2 57  ? -37.406 -1.226  30.807  1    44.61  ? 53  SER C CB  1 
ATOM   7070 O  OG  . SER D 2 57  ? -38.105 -0.664  31.917  1    52.6   ? 53  SER C OG  1 
ATOM   7071 N  N   . LEU D 2 58  ? -38.728 1.481   29.61   1    41.17  ? 54  LEU C N   1 
ATOM   7072 C  CA  . LEU D 2 58  ? -39.87  2.082   28.918  1    42.68  ? 54  LEU C CA  1 
ATOM   7073 C  C   . LEU D 2 58  ? -39.414 3       27.783  1    45.02  ? 54  LEU C C   1 
ATOM   7074 O  O   . LEU D 2 58  ? -39.967 2.921   26.679  1    53.96  ? 54  LEU C O   1 
ATOM   7075 C  CB  . LEU D 2 58  ? -40.892 2.723   29.862  1    40.68  ? 54  LEU C CB  1 
ATOM   7076 C  CG  . LEU D 2 58  ? -41.34  1.808   31.019  1    42.71  ? 54  LEU C CG  1 
ATOM   7077 C  CD1 . LEU D 2 58  ? -42.157 2.529   32.07   1    41.99  ? 54  LEU C CD1 1 
ATOM   7078 C  CD2 . LEU D 2 58  ? -42.076 0.56    30.551  1    37.94  ? 54  LEU C CD2 1 
ATOM   7079 N  N   . LEU D 2 59  ? -38.359 3.798   28.016  1    41.74  ? 55  LEU C N   1 
ATOM   7080 C  CA  . LEU D 2 59  ? -37.827 4.663   26.969  1    41.19  ? 55  LEU C CA  1 
ATOM   7081 C  C   . LEU D 2 59  ? -37.235 3.847   25.807  1    47.74  ? 55  LEU C C   1 
ATOM   7082 O  O   . LEU D 2 59  ? -37.21  4.316   24.665  1    50.49  ? 55  LEU C O   1 
ATOM   7083 C  CB  . LEU D 2 59  ? -36.785 5.633   27.516  1    40.78  ? 55  LEU C CB  1 
ATOM   7084 C  CG  . LEU D 2 59  ? -37.269 6.852   28.305  1    40.78  ? 55  LEU C CG  1 
ATOM   7085 C  CD1 . LEU D 2 59  ? -36.048 7.656   28.719  1    44.16  ? 55  LEU C CD1 1 
ATOM   7086 C  CD2 . LEU D 2 59  ? -38.203 7.74    27.537  1    37.93  ? 55  LEU C CD2 1 
ATOM   7087 N  N   . LYS D 2 60  ? -36.703 2.647   26.083  1    51.34  ? 56  LYS C N   1 
ATOM   7088 C  CA  . LYS D 2 60  ? -36.153 1.814   25.021  1    58.55  ? 56  LYS C CA  1 
ATOM   7089 C  C   . LYS D 2 60  ? -37.258 1.379   24.049  1    59.63  ? 56  LYS C C   1 
ATOM   7090 O  O   . LYS D 2 60  ? -36.989 1.079   22.9    1    60.87  ? 56  LYS C O   1 
ATOM   7091 C  CB  . LYS D 2 60  ? -35.35  0.62    25.561  1    60.34  ? 56  LYS C CB  1 
ATOM   7092 C  CG  . LYS D 2 60  ? -33.97  0.958   26.102  1    58.26  ? 56  LYS C CG  1 
ATOM   7093 C  CD  . LYS D 2 60  ? -33.075 -0.276  26.117  1    63.44  ? 56  LYS C CD  1 
ATOM   7094 C  CE  . LYS D 2 60  ? -32.358 -0.568  24.83   1    61.64  ? 56  LYS C CE  1 
ATOM   7095 N  NZ  . LYS D 2 60  ? -32.333 -2.021  24.633  1    58.78  ? 56  LYS C NZ  1 
ATOM   7096 N  N   . GLU D 2 61  ? -38.509 1.336   24.511  1    58.93  ? 57  GLU C N   1 
ATOM   7097 C  CA  . GLU D 2 61  ? -39.624 0.983   23.656  1    55.12  ? 57  GLU C CA  1 
ATOM   7098 C  C   . GLU D 2 61  ? -40.158 2.221   22.937  1    59.26  ? 57  GLU C C   1 
ATOM   7099 O  O   . GLU D 2 61  ? -40.475 2.171   21.755  1    63.89  ? 57  GLU C O   1 
ATOM   7100 C  CB  . GLU D 2 61  ? -40.715 0.396   24.547  1    59.14  ? 57  GLU C CB  1 
ATOM   7101 C  CG  . GLU D 2 61  ? -40.32  -0.949  25.148  1    55.09  ? 57  GLU C CG  1 
ATOM   7102 C  CD  . GLU D 2 61  ? -41.466 -1.913  25.332  1    62.15  ? 57  GLU C CD  1 
ATOM   7103 O  OE1 . GLU D 2 61  ? -42.631 -1.497  25.131  1    62.87  ? 57  GLU C OE1 1 
ATOM   7104 O  OE2 . GLU D 2 61  ? -41.194 -3.099  25.648  1    78.06  ? 57  GLU C OE2 1 
ATOM   7105 N  N   . LEU D 2 62  ? -40.24  3.345   23.647  1    54.9   ? 58  LEU C N   1 
ATOM   7106 C  CA  . LEU D 2 62  ? -40.921 4.503   23.106  1    53.14  ? 58  LEU C CA  1 
ATOM   7107 C  C   . LEU D 2 62  ? -40     5.293   22.166  1    54.26  ? 58  LEU C C   1 
ATOM   7108 O  O   . LEU D 2 62  ? -39.274 6.179   22.615  1    56.67  ? 58  LEU C O   1 
ATOM   7109 C  CB  . LEU D 2 62  ? -41.417 5.351   24.285  1    52.46  ? 58  LEU C CB  1 
ATOM   7110 C  CG  . LEU D 2 62  ? -42.34  4.691   25.317  1    50.77  ? 58  LEU C CG  1 
ATOM   7111 C  CD1 . LEU D 2 62  ? -42.528 5.575   26.529  1    50.64  ? 58  LEU C CD1 1 
ATOM   7112 C  CD2 . LEU D 2 62  ? -43.696 4.361   24.745  1    52.5   ? 58  LEU C CD2 1 
ATOM   7113 N  N   . ASN D 2 63  ? -40.07  5.017   20.852  1    53.94  ? 59  ASN C N   1 
ATOM   7114 C  CA  . ASN D 2 63  ? -39.421 5.871   19.868  1    53.67  ? 59  ASN C CA  1 
ATOM   7115 C  C   . ASN D 2 63  ? -40.457 6.711   19.13   1    50.84  ? 59  ASN C C   1 
ATOM   7116 O  O   . ASN D 2 63  ? -41.2   6.189   18.311  1    53.82  ? 59  ASN C O   1 
ATOM   7117 C  CB  . ASN D 2 63  ? -38.473 5.105   18.95   1    69.79  ? 59  ASN C CB  1 
ATOM   7118 C  CG  . ASN D 2 63  ? -37.153 4.803   19.635  1    97.99  ? 59  ASN C CG  1 
ATOM   7119 O  OD1 . ASN D 2 63  ? -37.105 3.996   20.578  1    91.96  ? 59  ASN C OD1 1 
ATOM   7120 N  ND2 . ASN D 2 63  ? -36.083 5.459   19.197  1    104    ? 59  ASN C ND2 1 
ATOM   7121 N  N   . HIS D 2 64  ? -40.496 8.016   19.427  1    47.13  ? 60  HIS C N   1 
ATOM   7122 C  CA  . HIS D 2 64  ? -41.426 8.952   18.803  1    46.22  ? 60  HIS C CA  1 
ATOM   7123 C  C   . HIS D 2 64  ? -40.814 10.353  18.796  1    45.6   ? 60  HIS C C   1 
ATOM   7124 O  O   . HIS D 2 64  ? -39.998 10.682  19.656  1    48.58  ? 60  HIS C O   1 
ATOM   7125 C  CB  . HIS D 2 64  ? -42.755 8.941   19.56   1    43.3   ? 60  HIS C CB  1 
ATOM   7126 C  CG  . HIS D 2 64  ? -43.83  9.761   18.934  1    45.37  ? 60  HIS C CG  1 
ATOM   7127 N  ND1 . HIS D 2 64  ? -43.976 11.105  19.199  1    44.9   ? 60  HIS C ND1 1 
ATOM   7128 C  CD2 . HIS D 2 64  ? -44.839 9.435   18.102  1    43     ? 60  HIS C CD2 1 
ATOM   7129 C  CE1 . HIS D 2 64  ? -45.019 11.569  18.523  1    44.72  ? 60  HIS C CE1 1 
ATOM   7130 N  NE2 . HIS D 2 64  ? -45.574 10.572  17.873  1    42.48  ? 60  HIS C NE2 1 
ATOM   7131 N  N   . PRO D 2 65  ? -41.132 11.226  17.82   1    44.81  ? 61  PRO C N   1 
ATOM   7132 C  CA  . PRO D 2 65  ? -40.517 12.559  17.778  1    48.79  ? 61  PRO C CA  1 
ATOM   7133 C  C   . PRO D 2 65  ? -40.83  13.492  18.944  1    48.63  ? 61  PRO C C   1 
ATOM   7134 O  O   . PRO D 2 65  ? -40.111 14.473  19.126  1    50.91  ? 61  PRO C O   1 
ATOM   7135 C  CB  . PRO D 2 65  ? -40.891 13.196  16.433  1    44.45  ? 61  PRO C CB  1 
ATOM   7136 C  CG  . PRO D 2 65  ? -41.7   12.119  15.705  1    44.01  ? 61  PRO C CG  1 
ATOM   7137 C  CD  . PRO D 2 65  ? -42.008 10.976  16.671  1    43.67  ? 61  PRO C CD  1 
ATOM   7138 N  N   . ASN D 2 66  ? -41.877 13.159  19.718  1    43.81  ? 62  ASN C N   1 
ATOM   7139 C  CA  . ASN D 2 66  ? -42.352 14.005  20.799  1    40.98  ? 62  ASN C CA  1 
ATOM   7140 C  C   . ASN D 2 66  ? -42.101 13.358  22.156  1    43.36  ? 62  ASN C C   1 
ATOM   7141 O  O   . ASN D 2 66  ? -42.647 13.798  23.171  1    44.43  ? 62  ASN C O   1 
ATOM   7142 C  CB  . ASN D 2 66  ? -43.819 14.347  20.605  1    39.24  ? 62  ASN C CB  1 
ATOM   7143 C  CG  . ASN D 2 66  ? -43.991 15.185  19.368  1    42.91  ? 62  ASN C CG  1 
ATOM   7144 O  OD1 . ASN D 2 66  ? -44.669 14.752  18.436  1    52.32  ? 62  ASN C OD1 1 
ATOM   7145 N  ND2 . ASN D 2 66  ? -43.394 16.37   19.322  1    39.11  ? 62  ASN C ND2 1 
ATOM   7146 N  N   . ILE D 2 67  ? -41.284 12.3    22.16   1    41.17  ? 63  ILE C N   1 
ATOM   7147 C  CA  . ILE D 2 67  ? -40.755 11.721  23.38   1    36.33  ? 63  ILE C CA  1 
ATOM   7148 C  C   . ILE D 2 67  ? -39.237 11.788  23.306  1    37.32  ? 63  ILE C C   1 
ATOM   7149 O  O   . ILE D 2 67  ? -38.639 11.354  22.314  1    36.19  ? 63  ILE C O   1 
ATOM   7150 C  CB  . ILE D 2 67  ? -41.232 10.268  23.531  1    34.81  ? 63  ILE C CB  1 
ATOM   7151 C  CG1 . ILE D 2 67  ? -42.76  10.168  23.583  1    34.14  ? 63  ILE C CG1 1 
ATOM   7152 C  CG2 . ILE D 2 67  ? -40.565 9.616   24.739  1    32.31  ? 63  ILE C CG2 1 
ATOM   7153 C  CD1 . ILE D 2 67  ? -43.265 8.735   23.537  1    34.38  ? 63  ILE C CD1 1 
ATOM   7154 N  N   . VAL D 2 68  ? -38.643 12.305  24.39   1    39.64  ? 64  VAL C N   1 
ATOM   7155 C  CA  . VAL D 2 68  ? -37.2   12.429  24.518  1    41.37  ? 64  VAL C CA  1 
ATOM   7156 C  C   . VAL D 2 68  ? -36.542 11.079  24.191  1    44.86  ? 64  VAL C C   1 
ATOM   7157 O  O   . VAL D 2 68  ? -37.037 9.992   24.531  1    42.62  ? 64  VAL C O   1 
ATOM   7158 C  CB  . VAL D 2 68  ? -36.792 12.982  25.899  1    39.06  ? 64  VAL C CB  1 
ATOM   7159 C  CG1 . VAL D 2 68  ? -36.88  11.914  26.982  1    36.07  ? 64  VAL C CG1 1 
ATOM   7160 C  CG2 . VAL D 2 68  ? -35.39  13.576  25.887  1    38.4   ? 64  VAL C CG2 1 
ATOM   7161 N  N   . LYS D 2 69  ? -35.417 11.183  23.487  1    43.51  ? 65  LYS C N   1 
ATOM   7162 C  CA  . LYS D 2 69  ? -34.746 10.018  22.944  1    47.55  ? 65  LYS C CA  1 
ATOM   7163 C  C   . LYS D 2 69  ? -33.64  9.66    23.926  1    43.41  ? 65  LYS C C   1 
ATOM   7164 O  O   . LYS D 2 69  ? -32.827 10.51   24.275  1    42.56  ? 65  LYS C O   1 
ATOM   7165 C  CB  . LYS D 2 69  ? -34.241 10.377  21.536  1    51.84  ? 65  LYS C CB  1 
ATOM   7166 C  CG  . LYS D 2 69  ? -34.404 9.332   20.46   1    65.37  ? 65  LYS C CG  1 
ATOM   7167 C  CD  . LYS D 2 69  ? -33.258 8.325   20.426  1    85.3   ? 65  LYS C CD  1 
ATOM   7168 C  CE  . LYS D 2 69  ? -33.425 7.067   19.606  1    82.86  ? 65  LYS C CE  1 
ATOM   7169 N  NZ  . LYS D 2 69  ? -32.098 6.493   19.34   1    79.57  ? 65  LYS C NZ  1 
ATOM   7170 N  N   . LEU D 2 70  ? -33.658 8.415   24.403  1    42.62  ? 66  LEU C N   1 
ATOM   7171 C  CA  . LEU D 2 70  ? -32.544 7.827   25.131  1    41.03  ? 66  LEU C CA  1 
ATOM   7172 C  C   . LEU D 2 70  ? -31.565 7.241   24.106  1    42.93  ? 66  LEU C C   1 
ATOM   7173 O  O   . LEU D 2 70  ? -31.93  6.355   23.333  1    43.65  ? 66  LEU C O   1 
ATOM   7174 C  CB  . LEU D 2 70  ? -33.103 6.75    26.063  1    38.28  ? 66  LEU C CB  1 
ATOM   7175 C  CG  . LEU D 2 70  ? -32.086 6.053   26.972  1    39.42  ? 66  LEU C CG  1 
ATOM   7176 C  CD1 . LEU D 2 70  ? -31.317 7.041   27.873  1    39.23  ? 66  LEU C CD1 1 
ATOM   7177 C  CD2 . LEU D 2 70  ? -32.775 4.993   27.798  1    38.83  ? 66  LEU C CD2 1 
ATOM   7178 N  N   . LEU D 2 71  ? -30.331 7.761   24.08   1    40.84  ? 67  LEU C N   1 
ATOM   7179 C  CA  . LEU D 2 71  ? -29.37  7.441   23.029  1    40.98  ? 67  LEU C CA  1 
ATOM   7180 C  C   . LEU D 2 71  ? -28.507 6.233   23.414  1    41.44  ? 67  LEU C C   1 
ATOM   7181 O  O   . LEU D 2 71  ? -28.135 5.44    22.55   1    43.24  ? 67  LEU C O   1 
ATOM   7182 C  CB  . LEU D 2 71  ? -28.494 8.657   22.723  1    39.02  ? 67  LEU C CB  1 
ATOM   7183 C  CG  . LEU D 2 71  ? -29.218 9.939   22.286  1    37.85  ? 67  LEU C CG  1 
ATOM   7184 C  CD1 . LEU D 2 71  ? -28.242 11.109  22.29   1    38.27  ? 67  LEU C CD1 1 
ATOM   7185 C  CD2 . LEU D 2 71  ? -29.87  9.859   20.899  1    36.53  ? 67  LEU C CD2 1 
ATOM   7186 N  N   . ASP D 2 72  ? -28.188 6.092   24.706  1    39.32  ? 68  ASP C N   1 
ATOM   7187 C  CA  . ASP D 2 72  ? -27.245 5.07    25.137  1    41.42  ? 68  ASP C CA  1 
ATOM   7188 C  C   . ASP D 2 72  ? -27.351 4.871   26.654  1    42.9   ? 68  ASP C C   1 
ATOM   7189 O  O   . ASP D 2 72  ? -27.915 5.693   27.39   1    40.82  ? 68  ASP C O   1 
ATOM   7190 C  CB  . ASP D 2 72  ? -25.831 5.4     24.662  1    42.15  ? 68  ASP C CB  1 
ATOM   7191 C  CG  . ASP D 2 72  ? -24.868 4.23    24.52   1    44.68  ? 68  ASP C CG  1 
ATOM   7192 O  OD1 . ASP D 2 72  ? -25.288 3.086   24.76   1    46.45  ? 68  ASP C OD1 1 
ATOM   7193 O  OD2 . ASP D 2 72  ? -23.697 4.468   24.154  1    49.11  ? 68  ASP C OD2 1 
ATOM   7194 N  N   . VAL D 2 73  ? -26.78  3.76    27.125  1    42.14  ? 69  VAL C N   1 
ATOM   7195 C  CA  . VAL D 2 73  ? -26.727 3.488   28.548  1    42.79  ? 69  VAL C CA  1 
ATOM   7196 C  C   . VAL D 2 73  ? -25.352 2.911   28.83   1    46     ? 69  VAL C C   1 
ATOM   7197 O  O   . VAL D 2 73  ? -25.068 1.779   28.445  1    49.69  ? 69  VAL C O   1 
ATOM   7198 C  CB  . VAL D 2 73  ? -27.828 2.526   29.03   1    41.22  ? 69  VAL C CB  1 
ATOM   7199 C  CG1 . VAL D 2 73  ? -27.796 2.367   30.551  1    41.99  ? 69  VAL C CG1 1 
ATOM   7200 C  CG2 . VAL D 2 73  ? -29.203 2.984   28.573  1    41.09  ? 69  VAL C CG2 1 
ATOM   7201 N  N   . ILE D 2 74  ? -24.517 3.697   29.511  1    48.2   ? 70  ILE C N   1 
ATOM   7202 C  CA  . ILE D 2 74  ? -23.123 3.326   29.666  1    52.12  ? 70  ILE C CA  1 
ATOM   7203 C  C   . ILE D 2 74  ? -22.938 2.767   31.063  1    53.48  ? 70  ILE C C   1 
ATOM   7204 O  O   . ILE D 2 74  ? -23.308 3.406   32.035  1    53.11  ? 70  ILE C O   1 
ATOM   7205 C  CB  . ILE D 2 74  ? -22.187 4.506   29.332  1    53.04  ? 70  ILE C CB  1 
ATOM   7206 C  CG1 . ILE D 2 74  ? -22.234 4.793   27.814  1    49.79  ? 70  ILE C CG1 1 
ATOM   7207 C  CG2 . ILE D 2 74  ? -20.767 4.229   29.834  1    50.95  ? 70  ILE C CG2 1 
ATOM   7208 C  CD1 . ILE D 2 74  ? -21.658 6.125   27.39   1    55.83  ? 70  ILE C CD1 1 
ATOM   7209 N  N   . HIS D 2 75  ? -22.395 1.549   31.123  1    62.54  ? 71  HIS C N   1 
ATOM   7210 C  CA  . HIS D 2 75  ? -22.269 0.778   32.354  1    64.95  ? 71  HIS C CA  1 
ATOM   7211 C  C   . HIS D 2 75  ? -20.851 0.887   32.9    1    64.53  ? 71  HIS C C   1 
ATOM   7212 O  O   . HIS D 2 75  ? -19.889 0.919   32.146  1    64.14  ? 71  HIS C O   1 
ATOM   7213 C  CB  . HIS D 2 75  ? -22.578 -0.706  32.119  1    64.79  ? 71  HIS C CB  1 
ATOM   7214 C  CG  . HIS D 2 75  ? -23.998 -1.011  31.75   1    65.03  ? 71  HIS C CG  1 
ATOM   7215 N  ND1 . HIS D 2 75  ? -24.918 -1.432  32.689  1    63.28  ? 71  HIS C ND1 1 
ATOM   7216 C  CD2 . HIS D 2 75  ? -24.65  -0.98   30.562  1    63.72  ? 71  HIS C CD2 1 
ATOM   7217 C  CE1 . HIS D 2 75  ? -26.084 -1.642  32.086  1    65.44  ? 71  HIS C CE1 1 
ATOM   7218 N  NE2 . HIS D 2 75  ? -25.946 -1.373  30.798  1    63.16  ? 71  HIS C NE2 1 
ATOM   7219 N  N   . THR D 2 76  ? -20.757 1.009   34.224  1    70.69  ? 72  THR C N   1 
ATOM   7220 C  CA  . THR D 2 76  ? -19.56  0.68    34.986  1    70.06  ? 72  THR C CA  1 
ATOM   7221 C  C   . THR D 2 76  ? -20.038 -0.301  36.053  1    67     ? 72  THR C C   1 
ATOM   7222 O  O   . THR D 2 76  ? -21.217 -0.676  36.054  1    61.81  ? 72  THR C O   1 
ATOM   7223 C  CB  . THR D 2 76  ? -18.817 1.915   35.53   1    66.91  ? 72  THR C CB  1 
ATOM   7224 O  OG1 . THR D 2 76  ? -19.611 2.692   36.427  1    65.81  ? 72  THR C OG1 1 
ATOM   7225 C  CG2 . THR D 2 76  ? -18.366 2.867   34.435  1    65.45  ? 72  THR C CG2 1 
ATOM   7226 N  N   . GLU D 2 77  ? -19.124 -0.725  36.929  1    70.47  ? 73  GLU C N   1 
ATOM   7227 C  CA  . GLU D 2 77  ? -19.535 -1.506  38.083  1    71.95  ? 73  GLU C CA  1 
ATOM   7228 C  C   . GLU D 2 77  ? -20.254 -0.607  39.098  1    68.26  ? 73  GLU C C   1 
ATOM   7229 O  O   . GLU D 2 77  ? -21.153 -1.066  39.8    1    67.08  ? 73  GLU C O   1 
ATOM   7230 C  CB  . GLU D 2 77  ? -18.396 -2.36   38.641  1    78.15  ? 73  GLU C CB  1 
ATOM   7231 C  CG  . GLU D 2 77  ? -18.903 -3.271  39.753  1    93.78  ? 73  GLU C CG  1 
ATOM   7232 C  CD  . GLU D 2 77  ? -18.126 -4.543  40.017  1    109.7  ? 73  GLU C CD  1 
ATOM   7233 O  OE1 . GLU D 2 77  ? -18.674 -5.653  39.763  1    116.35 ? 73  GLU C OE1 1 
ATOM   7234 O  OE2 . GLU D 2 77  ? -16.97  -4.4    40.478  1    111.82 ? 73  GLU C OE2 1 
ATOM   7235 N  N   . ASN D 2 78  ? -19.897 0.691   39.131  1    67.37  ? 74  ASN C N   1 
ATOM   7236 C  CA  . ASN D 2 78  ? -20.315 1.615   40.185  1    61.76  ? 74  ASN C CA  1 
ATOM   7237 C  C   . ASN D 2 78  ? -21.362 2.64    39.751  1    56.49  ? 74  ASN C C   1 
ATOM   7238 O  O   . ASN D 2 78  ? -22.036 3.198   40.606  1    56.12  ? 74  ASN C O   1 
ATOM   7239 C  CB  . ASN D 2 78  ? -19.112 2.223   40.884  1    62.66  ? 74  ASN C CB  1 
ATOM   7240 C  CG  . ASN D 2 78  ? -18.522 1.187   41.808  1    68.67  ? 74  ASN C CG  1 
ATOM   7241 O  OD1 . ASN D 2 78  ? -19.107 0.864   42.858  1    71.95  ? 74  ASN C OD1 1 
ATOM   7242 N  ND2 . ASN D 2 78  ? -17.398 0.612   41.406  1    68.05  ? 74  ASN C ND2 1 
ATOM   7243 N  N   . LYS D 2 79  ? -21.527 2.865   38.442  1    55.61  ? 75  LYS C N   1 
ATOM   7244 C  CA  . LYS D 2 79  ? -22.399 3.929   37.962  1    56.33  ? 75  LYS C CA  1 
ATOM   7245 C  C   . LYS D 2 79  ? -23.138 3.56    36.686  1    52.21  ? 75  LYS C C   1 
ATOM   7246 O  O   . LYS D 2 79  ? -22.719 2.725   35.895  1    57.49  ? 75  LYS C O   1 
ATOM   7247 C  CB  . LYS D 2 79  ? -21.595 5.201   37.682  1    62.56  ? 75  LYS C CB  1 
ATOM   7248 C  CG  . LYS D 2 79  ? -21.798 6.304   38.706  1    73.26  ? 75  LYS C CG  1 
ATOM   7249 C  CD  . LYS D 2 79  ? -20.51  7.025   39.114  1    85.77  ? 75  LYS C CD  1 
ATOM   7250 C  CE  . LYS D 2 79  ? -20.676 7.712   40.46   1    92.55  ? 75  LYS C CE  1 
ATOM   7251 N  NZ  . LYS D 2 79  ? -19.521 8.493   40.914  1    86.52  ? 75  LYS C NZ  1 
ATOM   7252 N  N   . LEU D 2 80  ? -24.259 4.224   36.492  1    50.65  ? 76  LEU C N   1 
ATOM   7253 C  CA  . LEU D 2 80  ? -24.976 4.13    35.235  1    51.06  ? 76  LEU C CA  1 
ATOM   7254 C  C   . LEU D 2 80  ? -25.027 5.541   34.661  1    51.57  ? 76  LEU C C   1 
ATOM   7255 O  O   . LEU D 2 80  ? -25.348 6.501   35.375  1    55.82  ? 76  LEU C O   1 
ATOM   7256 C  CB  . LEU D 2 80  ? -26.381 3.631   35.568  1    50.75  ? 76  LEU C CB  1 
ATOM   7257 C  CG  . LEU D 2 80  ? -26.932 2.492   34.716  1    49.9   ? 76  LEU C CG  1 
ATOM   7258 C  CD1 . LEU D 2 80  ? -25.917 1.353   34.759  1    52.08  ? 76  LEU C CD1 1 
ATOM   7259 C  CD2 . LEU D 2 80  ? -28.255 2.083   35.335  1    47.97  ? 76  LEU C CD2 1 
ATOM   7260 N  N   . TYR D 2 81  ? -24.672 5.671   33.388  1    47.57  ? 77  TYR C N   1 
ATOM   7261 C  CA  . TYR D 2 81  ? -24.824 6.965   32.762  1    47.76  ? 77  TYR C CA  1 
ATOM   7262 C  C   . TYR D 2 81  ? -25.855 6.798   31.659  1    47.85  ? 77  TYR C C   1 
ATOM   7263 O  O   . TYR D 2 81  ? -25.739 5.879   30.852  1    51.03  ? 77  TYR C O   1 
ATOM   7264 C  CB  . TYR D 2 81  ? -23.482 7.372   32.175  1    49.16  ? 77  TYR C CB  1 
ATOM   7265 C  CG  . TYR D 2 81  ? -22.41  7.817   33.147  1    51.38  ? 77  TYR C CG  1 
ATOM   7266 C  CD1 . TYR D 2 81  ? -22.339 9.139   33.57   1    58.14  ? 77  TYR C CD1 1 
ATOM   7267 C  CD2 . TYR D 2 81  ? -21.401 6.955   33.526  1    54.14  ? 77  TYR C CD2 1 
ATOM   7268 C  CE1 . TYR D 2 81  ? -21.333 9.576   34.413  1    61.67  ? 77  TYR C CE1 1 
ATOM   7269 C  CE2 . TYR D 2 81  ? -20.381 7.377   34.358  1    61.16  ? 77  TYR C CE2 1 
ATOM   7270 C  CZ  . TYR D 2 81  ? -20.357 8.683   34.819  1    65.6   ? 77  TYR C CZ  1 
ATOM   7271 O  OH  . TYR D 2 81  ? -19.348 9.109   35.643  1    76.81  ? 77  TYR C OH  1 
ATOM   7272 N  N   . LEU D 2 82  ? -26.849 7.71    31.692  1    45.28  ? 78  LEU C N   1 
ATOM   7273 C  CA  . LEU D 2 82  ? -27.905 7.693   30.665  1    45.32  ? 78  LEU C CA  1 
ATOM   7274 C  C   . LEU D 2 82  ? -27.603 8.838   29.703  1    43.96  ? 78  LEU C C   1 
ATOM   7275 O  O   . LEU D 2 82  ? -27.454 9.97    30.162  1    46.81  ? 78  LEU C O   1 
ATOM   7276 C  CB  . LEU D 2 82  ? -29.251 7.83    31.368  1    47.3   ? 78  LEU C CB  1 
ATOM   7277 C  CG  . LEU D 2 82  ? -29.959 6.53    31.758  1    47.69  ? 78  LEU C CG  1 
ATOM   7278 C  CD1 . LEU D 2 82  ? -29.155 5.735   32.767  1    45.45  ? 78  LEU C CD1 1 
ATOM   7279 C  CD2 . LEU D 2 82  ? -31.327 6.86    32.316  1    49.01  ? 78  LEU C CD2 1 
ATOM   7280 N  N   . VAL D 2 83  ? -27.474 8.506   28.401  1    42.53  ? 79  VAL C N   1 
ATOM   7281 C  CA  . VAL D 2 83  ? -27.129 9.537   27.444  1    40.75  ? 79  VAL C CA  1 
ATOM   7282 C  C   . VAL D 2 83  ? -28.386 9.884   26.673  1    39.88  ? 79  VAL C C   1 
ATOM   7283 O  O   . VAL D 2 83  ? -28.937 9.02    26      1    41.05  ? 79  VAL C O   1 
ATOM   7284 C  CB  . VAL D 2 83  ? -25.999 9.078   26.512  1    40.22  ? 79  VAL C CB  1 
ATOM   7285 C  CG1 . VAL D 2 83  ? -25.597 10.197  25.572  1    40.37  ? 79  VAL C CG1 1 
ATOM   7286 C  CG2 . VAL D 2 83  ? -24.788 8.635   27.319  1    38.87  ? 79  VAL C CG2 1 
ATOM   7287 N  N   . PHE D 2 84  ? -28.841 11.134  26.812  1    39.97  ? 80  PHE C N   1 
ATOM   7288 C  CA  . PHE D 2 84  ? -30.085 11.582  26.193  1    38.69  ? 80  PHE C CA  1 
ATOM   7289 C  C   . PHE D 2 84  ? -29.802 12.582  25.086  1    38.45  ? 80  PHE C C   1 
ATOM   7290 O  O   . PHE D 2 84  ? -28.726 13.182  25.03   1    40.45  ? 80  PHE C O   1 
ATOM   7291 C  CB  . PHE D 2 84  ? -30.935 12.331  27.221  1    37.73  ? 80  PHE C CB  1 
ATOM   7292 C  CG  . PHE D 2 84  ? -31.654 11.461  28.233  1    40.83  ? 80  PHE C CG  1 
ATOM   7293 C  CD1 . PHE D 2 84  ? -32.903 10.91   27.943  1    43.11  ? 80  PHE C CD1 1 
ATOM   7294 C  CD2 . PHE D 2 84  ? -31.086 11.188  29.472  1    41.79  ? 80  PHE C CD2 1 
ATOM   7295 C  CE1 . PHE D 2 84  ? -33.578 10.119  28.871  1    40.98  ? 80  PHE C CE1 1 
ATOM   7296 C  CE2 . PHE D 2 84  ? -31.77  10.406  30.388  1    39.06  ? 80  PHE C CE2 1 
ATOM   7297 C  CZ  . PHE D 2 84  ? -33.007 9.873   30.088  1    38.46  ? 80  PHE C CZ  1 
ATOM   7298 N  N   . GLU D 2 85  ? -30.794 12.799  24.226  1    40.15  ? 81  GLU C N   1 
ATOM   7299 C  CA  . GLU D 2 85  ? -30.68  13.943  23.331  1    43.83  ? 81  GLU C CA  1 
ATOM   7300 C  C   . GLU D 2 85  ? -30.707 15.213  24.19   1    46.81  ? 81  GLU C C   1 
ATOM   7301 O  O   . GLU D 2 85  ? -31.285 15.238  25.277  1    44.8   ? 81  GLU C O   1 
ATOM   7302 C  CB  . GLU D 2 85  ? -31.725 13.904  22.213  1    41.61  ? 81  GLU C CB  1 
ATOM   7303 C  CG  . GLU D 2 85  ? -33.164 13.991  22.704  1    43.22  ? 81  GLU C CG  1 
ATOM   7304 C  CD  . GLU D 2 85  ? -34.168 14.284  21.613  1    44.43  ? 81  GLU C CD  1 
ATOM   7305 O  OE1 . GLU D 2 85  ? -33.954 15.226  20.824  1    46.95  ? 81  GLU C OE1 1 
ATOM   7306 O  OE2 . GLU D 2 85  ? -35.197 13.594  21.589  1    44.48  ? 81  GLU C OE2 1 
ATOM   7307 N  N   . PHE D 2 86  ? -30.053 16.27   23.706  1    47.51  ? 82  PHE C N   1 
ATOM   7308 C  CA  . PHE D 2 86  ? -30.007 17.5    24.466  1    41.76  ? 82  PHE C CA  1 
ATOM   7309 C  C   . PHE D 2 86  ? -31.103 18.409  23.956  1    42.1   ? 82  PHE C C   1 
ATOM   7310 O  O   . PHE D 2 86  ? -31.252 18.568  22.754  1    41.09  ? 82  PHE C O   1 
ATOM   7311 C  CB  . PHE D 2 86  ? -28.724 18.277  24.209  1    44.21  ? 82  PHE C CB  1 
ATOM   7312 C  CG  . PHE D 2 86  ? -28.757 19.64   24.874  1    48.42  ? 82  PHE C CG  1 
ATOM   7313 C  CD1 . PHE D 2 86  ? -28.705 19.752  26.264  1    45.63  ? 82  PHE C CD1 1 
ATOM   7314 C  CD2 . PHE D 2 86  ? -28.861 20.803  24.104  1    49.78  ? 82  PHE C CD2 1 
ATOM   7315 C  CE1 . PHE D 2 86  ? -28.716 21.011  26.861  1    49.26  ? 82  PHE C CE1 1 
ATOM   7316 C  CE2 . PHE D 2 86  ? -28.858 22.056  24.706  1    48.33  ? 82  PHE C CE2 1 
ATOM   7317 C  CZ  . PHE D 2 86  ? -28.805 22.159  26.082  1    49.05  ? 82  PHE C CZ  1 
ATOM   7318 N  N   . LEU D 2 87  ? -31.868 18.988  24.88   1    44.25  ? 83  LEU C N   1 
ATOM   7319 C  CA  . LEU D 2 87  ? -32.872 19.967  24.496  1    45.18  ? 83  LEU C CA  1 
ATOM   7320 C  C   . LEU D 2 87  ? -32.654 21.243  25.305  1    46.74  ? 83  LEU C C   1 
ATOM   7321 O  O   . LEU D 2 87  ? -32.393 21.199  26.508  1    44.85  ? 83  LEU C O   1 
ATOM   7322 C  CB  . LEU D 2 87  ? -34.25  19.342  24.683  1    42.44  ? 83  LEU C CB  1 
ATOM   7323 C  CG  . LEU D 2 87  ? -34.543 18.139  23.788  1    42.13  ? 83  LEU C CG  1 
ATOM   7324 C  CD1 . LEU D 2 87  ? -35.48  17.174  24.452  1    45.61  ? 83  LEU C CD1 1 
ATOM   7325 C  CD2 . LEU D 2 87  ? -35.174 18.579  22.5    1    44.92  ? 83  LEU C CD2 1 
ATOM   7326 N  N   . HIS D 2 88  ? -32.687 22.359  24.576  1    52.24  ? 84  HIS C N   1 
ATOM   7327 C  CA  . HIS D 2 88  ? -32.417 23.72   25.015  1    58.72  ? 84  HIS C CA  1 
ATOM   7328 C  C   . HIS D 2 88  ? -32.939 24.038  26.431  1    57.05  ? 84  HIS C C   1 
ATOM   7329 O  O   . HIS D 2 88  ? -32.181 24.573  27.26   1    51.54  ? 84  HIS C O   1 
ATOM   7330 C  CB  . HIS D 2 88  ? -33     24.651  23.952  1    63.74  ? 84  HIS C CB  1 
ATOM   7331 C  CG  . HIS D 2 88  ? -32.667 26.071  24.176  1    78.52  ? 84  HIS C CG  1 
ATOM   7332 N  ND1 . HIS D 2 88  ? -33.593 26.964  24.668  1    81.96  ? 84  HIS C ND1 1 
ATOM   7333 C  CD2 . HIS D 2 88  ? -31.533 26.76   23.964  1    90.59  ? 84  HIS C CD2 1 
ATOM   7334 C  CE1 . HIS D 2 88  ? -33.022 28.162  24.759  1    91.61  ? 84  HIS C CE1 1 
ATOM   7335 N  NE2 . HIS D 2 88  ? -31.772 28.063  24.334  1    95.43  ? 84  HIS C NE2 1 
ATOM   7336 N  N   . GLN D 2 89  ? -34.239 23.774  26.696  1    47.82  ? 85  GLN C N   1 
ATOM   7337 C  CA  . GLN D 2 89  ? -34.795 24.038  28.016  1    47.6   ? 85  GLN C CA  1 
ATOM   7338 C  C   . GLN D 2 89  ? -36.16  23.385  28.181  1    45.38  ? 85  GLN C C   1 
ATOM   7339 O  O   . GLN D 2 89  ? -36.709 22.851  27.227  1    46.65  ? 85  GLN C O   1 
ATOM   7340 C  CB  . GLN D 2 89  ? -34.889 25.535  28.328  1    51.77  ? 85  GLN C CB  1 
ATOM   7341 C  CG  . GLN D 2 89  ? -35.921 26.321  27.523  1    52.56  ? 85  GLN C CG  1 
ATOM   7342 C  CD  . GLN D 2 89  ? -35.92  27.792  27.892  1    58.33  ? 85  GLN C CD  1 
ATOM   7343 O  OE1 . GLN D 2 89  ? -35.194 28.232  28.793  1    58.36  ? 85  GLN C OE1 1 
ATOM   7344 N  NE2 . GLN D 2 89  ? -36.713 28.576  27.175  1    60.22  ? 85  GLN C NE2 1 
ATOM   7345 N  N   . ASP D 2 90  ? -36.718 23.478  29.395  1    44.2   ? 86  ASP C N   1 
ATOM   7346 C  CA  . ASP D 2 90  ? -38.049 22.969  29.682  1    44.3   ? 86  ASP C CA  1 
ATOM   7347 C  C   . ASP D 2 90  ? -39.129 24.064  29.609  1    44.94  ? 86  ASP C C   1 
ATOM   7348 O  O   . ASP D 2 90  ? -38.843 25.275  29.654  1    42.78  ? 86  ASP C O   1 
ATOM   7349 C  CB  . ASP D 2 90  ? -38.044 22.257  31.023  1    46.75  ? 86  ASP C CB  1 
ATOM   7350 C  CG  . ASP D 2 90  ? -37.78  23.157  32.216  1    49.79  ? 86  ASP C CG  1 
ATOM   7351 O  OD1 . ASP D 2 90  ? -38.565 24.087  32.436  1    48.7   ? 86  ASP C OD1 1 
ATOM   7352 O  OD2 . ASP D 2 90  ? -36.778 22.924  32.906  1    59.56  ? 86  ASP C OD2 1 
ATOM   7353 N  N   . LEU D 2 91  ? -40.392 23.604  29.591  1    40.9   ? 87  LEU C N   1 
ATOM   7354 C  CA  . LEU D 2 91  ? -41.543 24.457  29.353  1    41.64  ? 87  LEU C CA  1 
ATOM   7355 C  C   . LEU D 2 91  ? -41.71  25.449  30.504  1    45.42  ? 87  LEU C C   1 
ATOM   7356 O  O   . LEU D 2 91  ? -42.055 26.616  30.281  1    46.1   ? 87  LEU C O   1 
ATOM   7357 C  CB  . LEU D 2 91  ? -42.787 23.594  29.152  1    40.07  ? 87  LEU C CB  1 
ATOM   7358 C  CG  . LEU D 2 91  ? -44.049 24.346  28.707  1    40.81  ? 87  LEU C CG  1 
ATOM   7359 C  CD1 . LEU D 2 91  ? -43.831 24.99   27.349  1    42.16  ? 87  LEU C CD1 1 
ATOM   7360 C  CD2 . LEU D 2 91  ? -45.248 23.422  28.644  1    36.86  ? 87  LEU C CD2 1 
ATOM   7361 N  N   . LYS D 2 92  ? -41.405 25.021  31.721  1    42.5   ? 88  LYS C N   1 
ATOM   7362 C  CA  . LYS D 2 92  ? -41.499 25.947  32.872  1    44.65  ? 88  LYS C CA  1 
ATOM   7363 C  C   . LYS D 2 92  ? -40.521 27.11   32.678  1    47.36  ? 88  LYS C C   1 
ATOM   7364 O  O   . LYS D 2 92  ? -40.918 28.246  32.941  1    56.49  ? 88  LYS C O   1 
ATOM   7365 C  CB  . LYS D 2 92  ? -41.245 25.242  34.205  1    44.05  ? 88  LYS C CB  1 
ATOM   7366 C  CG  . LYS D 2 92  ? -41.309 26.163  35.403  1    50.89  ? 88  LYS C CG  1 
ATOM   7367 C  CD  . LYS D 2 92  ? -42.671 26.81   35.597  1    56.61  ? 88  LYS C CD  1 
ATOM   7368 C  CE  . LYS D 2 92  ? -42.725 27.569  36.88   1    59.92  ? 88  LYS C CE  1 
ATOM   7369 N  NZ  . LYS D 2 92  ? -43.949 28.365  36.975  1    60.19  ? 88  LYS C NZ  1 
ATOM   7370 N  N   . LYS D 2 93  ? -39.306 26.842  32.216  1    47.14  ? 89  LYS C N   1 
ATOM   7371 C  CA  . LYS D 2 93  ? -38.353 27.939  32.127  1    47.71  ? 89  LYS C CA  1 
ATOM   7372 C  C   . LYS D 2 93  ? -38.779 28.898  31.028  1    43.92  ? 89  LYS C C   1 
ATOM   7373 O  O   . LYS D 2 93  ? -38.599 30.11   31.171  1    43.41  ? 89  LYS C O   1 
ATOM   7374 C  CB  . LYS D 2 93  ? -36.928 27.481  31.802  1    53.48  ? 89  LYS C CB  1 
ATOM   7375 C  CG  . LYS D 2 93  ? -36.098 27.044  33.007  1    66.21  ? 89  LYS C CG  1 
ATOM   7376 C  CD  . LYS D 2 93  ? -34.61  27.402  32.896  1    81.28  ? 89  LYS C CD  1 
ATOM   7377 C  CE  . LYS D 2 93  ? -33.794 26.701  33.953  1    81.23  ? 89  LYS C CE  1 
ATOM   7378 N  NZ  . LYS D 2 93  ? -34.202 25.29   34.056  1    75.07  ? 89  LYS C NZ  1 
ATOM   7379 N  N   . PHE D 2 94  ? -39.301 28.309  29.939  1    42     ? 90  PHE C N   1 
ATOM   7380 C  CA  . PHE D 2 94  ? -39.787 29.044  28.784  1    45.62  ? 90  PHE C CA  1 
ATOM   7381 C  C   . PHE D 2 94  ? -40.929 29.999  29.174  1    51.34  ? 90  PHE C C   1 
ATOM   7382 O  O   . PHE D 2 94  ? -40.911 31.186  28.79   1    53.15  ? 90  PHE C O   1 
ATOM   7383 C  CB  . PHE D 2 94  ? -40.238 28.069  27.697  1    43.63  ? 90  PHE C CB  1 
ATOM   7384 C  CG  . PHE D 2 94  ? -40.712 28.785  26.438  1    46.09  ? 90  PHE C CG  1 
ATOM   7385 C  CD1 . PHE D 2 94  ? -39.881 29.698  25.784  1    46.68  ? 90  PHE C CD1 1 
ATOM   7386 C  CD2 . PHE D 2 94  ? -42.009 28.59   25.949  1    45.06  ? 90  PHE C CD2 1 
ATOM   7387 C  CE1 . PHE D 2 94  ? -40.339 30.387  24.659  1    47.33  ? 90  PHE C CE1 1 
ATOM   7388 C  CE2 . PHE D 2 94  ? -42.461 29.269  24.824  1    44.81  ? 90  PHE C CE2 1 
ATOM   7389 C  CZ  . PHE D 2 94  ? -41.623 30.164  24.18   1    46.73  ? 90  PHE C CZ  1 
ATOM   7390 N  N   . MET D 2 95  ? -41.923 29.469  29.918  1    47.53  ? 91  MET C N   1 
ATOM   7391 C  CA  . MET D 2 95  ? -43.059 30.251  30.387  1    48.37  ? 91  MET C CA  1 
ATOM   7392 C  C   . MET D 2 95  ? -42.588 31.417  31.255  1    48.98  ? 91  MET C C   1 
ATOM   7393 O  O   . MET D 2 95  ? -42.978 32.562  31.022  1    50.41  ? 91  MET C O   1 
ATOM   7394 C  CB  . MET D 2 95  ? -44.056 29.365  31.136  1    48.15  ? 91  MET C CB  1 
ATOM   7395 C  CG  . MET D 2 95  ? -44.857 28.465  30.215  1    50.38  ? 91  MET C CG  1 
ATOM   7396 S  SD  . MET D 2 95  ? -46.186 27.488  30.951  1    57.23  ? 91  MET C SD  1 
ATOM   7397 C  CE  . MET D 2 95  ? -45.289 26.354  32.018  1    46.57  ? 91  MET C CE  1 
ATOM   7398 N  N   . ASP D 2 96  ? -41.734 31.116  32.237  1    46.52  ? 92  ASP C N   1 
ATOM   7399 C  CA  . ASP D 2 96  ? -41.152 32.131  33.094  1    49.36  ? 92  ASP C CA  1 
ATOM   7400 C  C   . ASP D 2 96  ? -40.469 33.206  32.242  1    52.24  ? 92  ASP C C   1 
ATOM   7401 O  O   . ASP D 2 96  ? -40.621 34.401  32.495  1    49.89  ? 92  ASP C O   1 
ATOM   7402 C  CB  . ASP D 2 96  ? -40.218 31.502  34.117  1    51.53  ? 92  ASP C CB  1 
ATOM   7403 C  CG  . ASP D 2 96  ? -40.886 30.641  35.18   1    55.47  ? 92  ASP C CG  1 
ATOM   7404 O  OD1 . ASP D 2 96  ? -42.127 30.706  35.289  1    56.64  ? 92  ASP C OD1 1 
ATOM   7405 O  OD2 . ASP D 2 96  ? -40.173 29.863  35.856  1    59.66  ? 92  ASP C OD2 1 
ATOM   7406 N  N   . ALA D 2 97  ? -39.712 32.781  31.218  1    51.69  ? 93  ALA C N   1 
ATOM   7407 C  CA  . ALA D 2 97  ? -38.95  33.718  30.402  1    52.34  ? 93  ALA C CA  1 
ATOM   7408 C  C   . ALA D 2 97  ? -39.871 34.575  29.538  1    53.85  ? 93  ALA C C   1 
ATOM   7409 O  O   . ALA D 2 97  ? -39.461 35.65   29.11   1    54.29  ? 93  ALA C O   1 
ATOM   7410 C  CB  . ALA D 2 97  ? -37.964 32.974  29.544  1    49.6   ? 93  ALA C CB  1 
ATOM   7411 N  N   . SER D 2 98  ? -41.085 34.07   29.266  1    54.71  ? 94  SER C N   1 
ATOM   7412 C  CA  . SER D 2 98  ? -42.077 34.735  28.439  1    56.99  ? 94  SER C CA  1 
ATOM   7413 C  C   . SER D 2 98  ? -43.041 35.589  29.256  1    64.81  ? 94  SER C C   1 
ATOM   7414 O  O   . SER D 2 98  ? -44.159 35.793  28.802  1    70.87  ? 94  SER C O   1 
ATOM   7415 C  CB  . SER D 2 98  ? -42.885 33.722  27.703  1    51.01  ? 94  SER C CB  1 
ATOM   7416 O  OG  . SER D 2 98  ? -42.064 32.987  26.823  1    50.73  ? 94  SER C OG  1 
ATOM   7417 N  N   . ALA D 2 99  ? -42.649 36.068  30.445  1    69.22  ? 95  ALA C N   1 
ATOM   7418 C  CA  . ALA D 2 99  ? -43.585 36.676  31.385  1    71.34  ? 95  ALA C CA  1 
ATOM   7419 C  C   . ALA D 2 99  ? -44.032 38.057  30.902  1    74.85  ? 95  ALA C C   1 
ATOM   7420 O  O   . ALA D 2 99  ? -45.141 38.506  31.196  1    77.83  ? 95  ALA C O   1 
ATOM   7421 C  CB  . ALA D 2 99  ? -42.955 36.771  32.749  1    68.8   ? 95  ALA C CB  1 
ATOM   7422 N  N   . LEU D 2 100 ? -43.163 38.723  30.146  1    76.65  ? 96  LEU C N   1 
ATOM   7423 C  CA  . LEU D 2 100 ? -43.429 40.092  29.752  1    84.68  ? 96  LEU C CA  1 
ATOM   7424 C  C   . LEU D 2 100 ? -43.665 40.191  28.246  1    89.3   ? 96  LEU C C   1 
ATOM   7425 O  O   . LEU D 2 100 ? -43.99  41.276  27.762  1    101.32 ? 96  LEU C O   1 
ATOM   7426 C  CB  . LEU D 2 100 ? -42.245 40.967  30.161  1    90.92  ? 96  LEU C CB  1 
ATOM   7427 C  CG  . LEU D 2 100 ? -41.763 40.827  31.607  1    88.96  ? 96  LEU C CG  1 
ATOM   7428 C  CD1 . LEU D 2 100 ? -40.781 41.96   31.904  1    90.55  ? 96  LEU C CD1 1 
ATOM   7429 C  CD2 . LEU D 2 100 ? -42.921 40.788  32.592  1    83.5   ? 96  LEU C CD2 1 
ATOM   7430 N  N   . THR D 2 101 ? -43.458 39.085  27.509  1    77.13  ? 97  THR C N   1 
ATOM   7431 C  CA  . THR D 2 101 ? -43.738 39.061  26.081  1    69.51  ? 97  THR C CA  1 
ATOM   7432 C  C   . THR D 2 101 ? -45.028 38.282  25.798  1    69.55  ? 97  THR C C   1 
ATOM   7433 O  O   . THR D 2 101 ? -45.592 38.394  24.72   1    74.29  ? 97  THR C O   1 
ATOM   7434 C  CB  . THR D 2 101 ? -42.546 38.511  25.291  1    68.63  ? 97  THR C CB  1 
ATOM   7435 O  OG1 . THR D 2 101 ? -42.372 37.127  25.591  1    59.25  ? 97  THR C OG1 1 
ATOM   7436 C  CG2 . THR D 2 101 ? -41.268 39.308  25.511  1    69.43  ? 97  THR C CG2 1 
ATOM   7437 N  N   . GLY D 2 102 ? -45.523 37.499  26.759  1    66.69  ? 98  GLY C N   1 
ATOM   7438 C  CA  . GLY D 2 102 ? -46.534 36.496  26.454  1    63.68  ? 98  GLY C CA  1 
ATOM   7439 C  C   . GLY D 2 102 ? -46     35.437  25.483  1    59.84  ? 98  GLY C C   1 
ATOM   7440 O  O   . GLY D 2 102 ? -44.925 35.604  24.916  1    55.59  ? 98  GLY C O   1 
ATOM   7441 N  N   . ILE D 2 103 ? -46.757 34.343  25.323  1    58.56  ? 99  ILE C N   1 
ATOM   7442 C  CA  . ILE D 2 103 ? -46.482 33.293  24.357  1    58.42  ? 99  ILE C CA  1 
ATOM   7443 C  C   . ILE D 2 103 ? -47.506 33.338  23.213  1    59.17  ? 99  ILE C C   1 
ATOM   7444 O  O   . ILE D 2 103 ? -48.714 33.239  23.43   1    61.67  ? 99  ILE C O   1 
ATOM   7445 C  CB  . ILE D 2 103 ? -46.547 31.933  25.069  1    58.47  ? 99  ILE C CB  1 
ATOM   7446 C  CG1 . ILE D 2 103 ? -45.589 31.84   26.246  1    61.73  ? 99  ILE C CG1 1 
ATOM   7447 C  CG2 . ILE D 2 103 ? -46.341 30.785  24.081  1    55.93  ? 99  ILE C CG2 1 
ATOM   7448 C  CD1 . ILE D 2 103 ? -45.61  30.471  26.93   1    58.61  ? 99  ILE C CD1 1 
ATOM   7449 N  N   . PRO D 2 104 ? -47.082 33.389  21.931  1    58.97  ? 100 PRO C N   1 
ATOM   7450 C  CA  . PRO D 2 104 ? -48.05  33.393  20.826  1    57.89  ? 100 PRO C CA  1 
ATOM   7451 C  C   . PRO D 2 104 ? -48.953 32.159  20.783  1    57.72  ? 100 PRO C C   1 
ATOM   7452 O  O   . PRO D 2 104 ? -48.512 31.033  21.025  1    55.57  ? 100 PRO C O   1 
ATOM   7453 C  CB  . PRO D 2 104 ? -47.196 33.555  19.553  1    55.35  ? 100 PRO C CB  1 
ATOM   7454 C  CG  . PRO D 2 104 ? -45.854 34.034  20.076  1    56.81  ? 100 PRO C CG  1 
ATOM   7455 C  CD  . PRO D 2 104 ? -45.682 33.434  21.474  1    56.52  ? 100 PRO C CD  1 
ATOM   7456 N  N   . LEU D 2 105 ? -50.23  32.387  20.487  1    60.82  ? 101 LEU C N   1 
ATOM   7457 C  CA  . LEU D 2 105 ? -51.226 31.285  20.448  1    62.34  ? 101 LEU C CA  1 
ATOM   7458 C  C   . LEU D 2 105 ? -50.811 30.196  19.454  1    57.67  ? 101 LEU C C   1 
ATOM   7459 O  O   . LEU D 2 105 ? -50.861 29.027  19.85   1    60.18  ? 101 LEU C O   1 
ATOM   7460 C  CB  . LEU D 2 105 ? -52.62  31.825  20.137  1    66.1   ? 101 LEU C CB  1 
ATOM   7461 C  CG  . LEU D 2 105 ? -53.235 32.752  21.188  1    73.03  ? 101 LEU C CG  1 
ATOM   7462 C  CD1 . LEU D 2 105 ? -54.552 33.348  20.722  1    67.23  ? 101 LEU C CD1 1 
ATOM   7463 C  CD2 . LEU D 2 105 ? -53.405 32.028  22.509  1    72.12  ? 101 LEU C CD2 1 
ATOM   7464 N  N   . PRO D 2 106 ? -50.445 30.467  18.185  1    56.5   ? 102 PRO C N   1 
ATOM   7465 C  CA  . PRO D 2 106 ? -50.039 29.361  17.324  1    56.69  ? 102 PRO C CA  1 
ATOM   7466 C  C   . PRO D 2 106 ? -49.001 28.43   17.945  1    54.08  ? 102 PRO C C   1 
ATOM   7467 O  O   . PRO D 2 106 ? -49.039 27.225  17.686  1    54.33  ? 102 PRO C O   1 
ATOM   7468 C  CB  . PRO D 2 106 ? -49.529 30.057  16.049  1    57.06  ? 102 PRO C CB  1 
ATOM   7469 C  CG  . PRO D 2 106 ? -50.217 31.406  16.039  1    54.68  ? 102 PRO C CG  1 
ATOM   7470 C  CD  . PRO D 2 106 ? -50.346 31.769  17.496  1    56.43  ? 102 PRO C CD  1 
ATOM   7471 N  N   . LEU D 2 107 ? -48.099 28.99   18.765  1    51     ? 103 LEU C N   1 
ATOM   7472 C  CA  . LEU D 2 107 ? -47.068 28.186  19.411  1    47.87  ? 103 LEU C CA  1 
ATOM   7473 C  C   . LEU D 2 107 ? -47.659 27.344  20.543  1    46.69  ? 103 LEU C C   1 
ATOM   7474 O  O   . LEU D 2 107 ? -47.254 26.197  20.74   1    44.25  ? 103 LEU C O   1 
ATOM   7475 C  CB  . LEU D 2 107 ? -45.896 29.039  19.894  1    47.07  ? 103 LEU C CB  1 
ATOM   7476 C  CG  . LEU D 2 107 ? -44.684 28.265  20.43   1    45.55  ? 103 LEU C CG  1 
ATOM   7477 C  CD1 . LEU D 2 107 ? -43.969 27.432  19.396  1    41.97  ? 103 LEU C CD1 1 
ATOM   7478 C  CD2 . LEU D 2 107 ? -43.708 29.211  21.087  1    47.86  ? 103 LEU C CD2 1 
ATOM   7479 N  N   . ILE D 2 108 ? -48.607 27.923  21.295  1    46.07  ? 104 ILE C N   1 
ATOM   7480 C  CA  . ILE D 2 108 ? -49.33  27.171  22.309  1    45.42  ? 104 ILE C CA  1 
ATOM   7481 C  C   . ILE D 2 108 ? -49.996 25.949  21.663  1    48.82  ? 104 ILE C C   1 
ATOM   7482 O  O   . ILE D 2 108 ? -49.784 24.798  22.076  1    49.97  ? 104 ILE C O   1 
ATOM   7483 C  CB  . ILE D 2 108 ? -50.336 28.057  23.068  1    43.1   ? 104 ILE C CB  1 
ATOM   7484 C  CG1 . ILE D 2 108 ? -49.629 29.186  23.799  1    41.54  ? 104 ILE C CG1 1 
ATOM   7485 C  CG2 . ILE D 2 108 ? -51.217 27.213  24.005  1    40.17  ? 104 ILE C CG2 1 
ATOM   7486 C  CD1 . ILE D 2 108 ? -50.543 30.057  24.641  1    41.21  ? 104 ILE C CD1 1 
ATOM   7487 N  N   . LYS D 2 109 ? -50.797 26.212  20.627  1    50.56  ? 105 LYS C N   1 
ATOM   7488 C  CA  . LYS D 2 109 ? -51.521 25.158  19.927  1    49.75  ? 105 LYS C CA  1 
ATOM   7489 C  C   . LYS D 2 109 ? -50.549 24.101  19.399  1    45.94  ? 105 LYS C C   1 
ATOM   7490 O  O   . LYS D 2 109 ? -50.863 22.913  19.422  1    44.85  ? 105 LYS C O   1 
ATOM   7491 C  CB  . LYS D 2 109 ? -52.315 25.799  18.784  1    50.19  ? 105 LYS C CB  1 
ATOM   7492 C  CG  . LYS D 2 109 ? -53.097 24.846  17.893  1    49.45  ? 105 LYS C CG  1 
ATOM   7493 C  CD  . LYS D 2 109 ? -53.883 25.64   16.851  1    47.29  ? 105 LYS C CD  1 
ATOM   7494 C  CE  . LYS D 2 109 ? -55.092 26.314  17.451  1    47.34  ? 105 LYS C CE  1 
ATOM   7495 N  NZ  . LYS D 2 109 ? -55.661 27.334  16.551  1    48.92  ? 105 LYS C NZ  1 
ATOM   7496 N  N   . SER D 2 110 ? -49.387 24.549  18.904  1    43.03  ? 106 SER C N   1 
ATOM   7497 C  CA  . SER D 2 110 ? -48.435 23.623  18.328  1    42.47  ? 106 SER C CA  1 
ATOM   7498 C  C   . SER D 2 110 ? -47.935 22.678  19.416  1    42.44  ? 106 SER C C   1 
ATOM   7499 O  O   . SER D 2 110 ? -47.86  21.464  19.202  1    40.45  ? 106 SER C O   1 
ATOM   7500 C  CB  . SER D 2 110 ? -47.291 24.329  17.677  1    42.11  ? 106 SER C CB  1 
ATOM   7501 O  OG  . SER D 2 110 ? -46.28  23.394  17.309  1    41.9   ? 106 SER C OG  1 
ATOM   7502 N  N   . TYR D 2 111 ? -47.6   23.275  20.575  1    39.55  ? 107 TYR C N   1 
ATOM   7503 C  CA  . TYR D 2 111 ? -47.025 22.531  21.668  1    37.35  ? 107 TYR C CA  1 
ATOM   7504 C  C   . TYR D 2 111 ? -48.068 21.555  22.203  1    40.17  ? 107 TYR C C   1 
ATOM   7505 O  O   . TYR D 2 111 ? -47.756 20.402  22.485  1    45.73  ? 107 TYR C O   1 
ATOM   7506 C  CB  . TYR D 2 111 ? -46.572 23.512  22.735  1    37.56  ? 107 TYR C CB  1 
ATOM   7507 C  CG  . TYR D 2 111 ? -45.222 24.167  22.522  1    39.48  ? 107 TYR C CG  1 
ATOM   7508 C  CD1 . TYR D 2 111 ? -44.36  23.755  21.512  1    38.78  ? 107 TYR C CD1 1 
ATOM   7509 C  CD2 . TYR D 2 111 ? -44.796 25.162  23.403  1    40.73  ? 107 TYR C CD2 1 
ATOM   7510 C  CE1 . TYR D 2 111 ? -43.103 24.328  21.378  1    42.73  ? 107 TYR C CE1 1 
ATOM   7511 C  CE2 . TYR D 2 111 ? -43.557 25.766  23.254  1    42.3   ? 107 TYR C CE2 1 
ATOM   7512 C  CZ  . TYR D 2 111 ? -42.708 25.344  22.243  1    44.29  ? 107 TYR C CZ  1 
ATOM   7513 O  OH  . TYR D 2 111 ? -41.483 25.942  22.108  1    46.92  ? 107 TYR C OH  1 
ATOM   7514 N  N   . LEU D 2 112 ? -49.315 22.003  22.324  1    40.65  ? 108 LEU C N   1 
ATOM   7515 C  CA  . LEU D 2 112 ? -50.339 21.126  22.858  1    42.14  ? 108 LEU C CA  1 
ATOM   7516 C  C   . LEU D 2 112 ? -50.542 19.944  21.918  1    42.89  ? 108 LEU C C   1 
ATOM   7517 O  O   . LEU D 2 112 ? -50.715 18.811  22.363  1    45.38  ? 108 LEU C O   1 
ATOM   7518 C  CB  . LEU D 2 112 ? -51.644 21.895  23.045  1    43.05  ? 108 LEU C CB  1 
ATOM   7519 C  CG  . LEU D 2 112 ? -52.806 21.05   23.577  1    44.4   ? 108 LEU C CG  1 
ATOM   7520 C  CD1 . LEU D 2 112 ? -52.465 20.391  24.9    1    41.87  ? 108 LEU C CD1 1 
ATOM   7521 C  CD2 . LEU D 2 112 ? -54.063 21.882  23.719  1    45.88  ? 108 LEU C CD2 1 
ATOM   7522 N  N   . PHE D 2 113 ? -50.544 20.234  20.615  1    44.11  ? 109 PHE C N   1 
ATOM   7523 C  CA  . PHE D 2 113 ? -50.79  19.224  19.602  1    48.39  ? 109 PHE C CA  1 
ATOM   7524 C  C   . PHE D 2 113 ? -49.709 18.147  19.68   1    47.89  ? 109 PHE C C   1 
ATOM   7525 O  O   . PHE D 2 113 ? -50.002 16.951  19.593  1    50.37  ? 109 PHE C O   1 
ATOM   7526 C  CB  . PHE D 2 113 ? -50.861 19.907  18.235  1    51.88  ? 109 PHE C CB  1 
ATOM   7527 C  CG  . PHE D 2 113 ? -51.185 18.996  17.057  1    50.22  ? 109 PHE C CG  1 
ATOM   7528 C  CD1 . PHE D 2 113 ? -52.415 18.343  16.986  1    50.47  ? 109 PHE C CD1 1 
ATOM   7529 C  CD2 . PHE D 2 113 ? -50.272 18.824  16.009  1    50.19  ? 109 PHE C CD2 1 
ATOM   7530 C  CE1 . PHE D 2 113 ? -52.72  17.523  15.905  1    51.18  ? 109 PHE C CE1 1 
ATOM   7531 C  CE2 . PHE D 2 113 ? -50.575 17.994  14.934  1    50.26  ? 109 PHE C CE2 1 
ATOM   7532 C  CZ  . PHE D 2 113 ? -51.798 17.345  14.883  1    50.84  ? 109 PHE C CZ  1 
ATOM   7533 N  N   . GLN D 2 114 ? -48.467 18.59   19.869  1    47.85  ? 110 GLN C N   1 
ATOM   7534 C  CA  . GLN D 2 114 ? -47.303 17.718  19.903  1    48.03  ? 110 GLN C CA  1 
ATOM   7535 C  C   . GLN D 2 114 ? -47.301 16.879  21.183  1    47.04  ? 110 GLN C C   1 
ATOM   7536 O  O   . GLN D 2 114 ? -46.971 15.686  21.137  1    47.19  ? 110 GLN C O   1 
ATOM   7537 C  CB  . GLN D 2 114 ? -46.023 18.546  19.793  1    44.62  ? 110 GLN C CB  1 
ATOM   7538 C  CG  . GLN D 2 114 ? -45.754 19.149  18.421  1    40.17  ? 110 GLN C CG  1 
ATOM   7539 C  CD  . GLN D 2 114 ? -44.437 19.895  18.439  1    46.38  ? 110 GLN C CD  1 
ATOM   7540 O  OE1 . GLN D 2 114 ? -43.358 19.295  18.592  1    49.09  ? 110 GLN C OE1 1 
ATOM   7541 N  NE2 . GLN D 2 114 ? -44.516 21.223  18.366  1    42.35  ? 110 GLN C NE2 1 
ATOM   7542 N  N   . LEU D 2 115 ? -47.651 17.514  22.317  1    44.64  ? 111 LEU C N   1 
ATOM   7543 C  CA  . LEU D 2 115 ? -47.736 16.821  23.597  1    43.13  ? 111 LEU C CA  1 
ATOM   7544 C  C   . LEU D 2 115 ? -48.768 15.687  23.508  1    47.39  ? 111 LEU C C   1 
ATOM   7545 O  O   . LEU D 2 115 ? -48.56  14.599  24.055  1    46.43  ? 111 LEU C O   1 
ATOM   7546 C  CB  . LEU D 2 115 ? -48.089 17.805  24.709  1    40.11  ? 111 LEU C CB  1 
ATOM   7547 C  CG  . LEU D 2 115 ? -47.049 18.871  25.059  1    38.87  ? 111 LEU C CG  1 
ATOM   7548 C  CD1 . LEU D 2 115 ? -47.622 19.838  26.043  1    37.37  ? 111 LEU C CD1 1 
ATOM   7549 C  CD2 . LEU D 2 115 ? -45.826 18.254  25.663  1    40.11  ? 111 LEU C CD2 1 
ATOM   7550 N  N   . LEU D 2 116 ? -49.881 15.946  22.802  1    44.52  ? 112 LEU C N   1 
ATOM   7551 C  CA  . LEU D 2 116 ? -50.939 14.963  22.685  1    44.18  ? 112 LEU C CA  1 
ATOM   7552 C  C   . LEU D 2 116 ? -50.488 13.819  21.786  1    47.12  ? 112 LEU C C   1 
ATOM   7553 O  O   . LEU D 2 116 ? -50.895 12.672  21.978  1    48.84  ? 112 LEU C O   1 
ATOM   7554 C  CB  . LEU D 2 116 ? -52.168 15.667  22.122  1    46.05  ? 112 LEU C CB  1 
ATOM   7555 C  CG  . LEU D 2 116 ? -52.922 16.542  23.119  1    44.48  ? 112 LEU C CG  1 
ATOM   7556 C  CD1 . LEU D 2 116 ? -53.823 17.502  22.381  1    45.61  ? 112 LEU C CD1 1 
ATOM   7557 C  CD2 . LEU D 2 116 ? -53.725 15.645  24.042  1    43.6   ? 112 LEU C CD2 1 
ATOM   7558 N  N   . GLN D 2 117 ? -49.646 14.134  20.796  1    49.05  ? 113 GLN C N   1 
ATOM   7559 C  CA  . GLN D 2 117 ? -49.135 13.096  19.912  1    50.27  ? 113 GLN C CA  1 
ATOM   7560 C  C   . GLN D 2 117 ? -48.181 12.186  20.681  1    47.55  ? 113 GLN C C   1 
ATOM   7561 O  O   . GLN D 2 117 ? -48.232 10.968  20.514  1    46.31  ? 113 GLN C O   1 
ATOM   7562 C  CB  . GLN D 2 117 ? -48.415 13.65   18.692  1    47.39  ? 113 GLN C CB  1 
ATOM   7563 C  CG  . GLN D 2 117 ? -49.345 14.306  17.69   1    53.89  ? 113 GLN C CG  1 
ATOM   7564 C  CD  . GLN D 2 117 ? -48.59  14.614  16.417  1    68.57  ? 113 GLN C CD  1 
ATOM   7565 O  OE1 . GLN D 2 117 ? -48.633 13.842  15.457  1    76.11  ? 113 GLN C OE1 1 
ATOM   7566 N  NE2 . GLN D 2 117 ? -47.812 15.689  16.411  1    68.31  ? 113 GLN C NE2 1 
ATOM   7567 N  N   . GLY D 2 118 ? -47.311 12.792  21.505  1    43.16  ? 114 GLY C N   1 
ATOM   7568 C  CA  . GLY D 2 118 ? -46.406 12.02   22.337  1    37.97  ? 114 GLY C CA  1 
ATOM   7569 C  C   . GLY D 2 118 ? -47.177 11.153  23.326  1    39.27  ? 114 GLY C C   1 
ATOM   7570 O  O   . GLY D 2 118 ? -46.816 9.991   23.562  1    40.52  ? 114 GLY C O   1 
ATOM   7571 N  N   . LEU D 2 119 ? -48.231 11.734  23.912  1    40.57  ? 115 LEU C N   1 
ATOM   7572 C  CA  . LEU D 2 119 ? -48.942 11.07   24.986  1    44.88  ? 115 LEU C CA  1 
ATOM   7573 C  C   . LEU D 2 119 ? -49.73  9.888   24.415  1    47.36  ? 115 LEU C C   1 
ATOM   7574 O  O   . LEU D 2 119 ? -49.736 8.788   24.994  1    47.99  ? 115 LEU C O   1 
ATOM   7575 C  CB  . LEU D 2 119 ? -49.816 12.064  25.745  1    41.43  ? 115 LEU C CB  1 
ATOM   7576 C  CG  . LEU D 2 119 ? -50.591 11.467  26.925  1    40.84  ? 115 LEU C CG  1 
ATOM   7577 C  CD1 . LEU D 2 119 ? -49.64  11.01   28.035  1    38.18  ? 115 LEU C CD1 1 
ATOM   7578 C  CD2 . LEU D 2 119 ? -51.651 12.45   27.432  1    38.38  ? 115 LEU C CD2 1 
ATOM   7579 N  N   . ALA D 2 120 ? -50.394 10.139  23.277  1    45.9   ? 116 ALA C N   1 
ATOM   7580 C  CA  . ALA D 2 120 ? -51.176 9.133   22.579  1    41.88  ? 116 ALA C CA  1 
ATOM   7581 C  C   . ALA D 2 120 ? -50.28  7.944   22.248  1    44.28  ? 116 ALA C C   1 
ATOM   7582 O  O   . ALA D 2 120 ? -50.743 6.807   22.286  1    44.66  ? 116 ALA C O   1 
ATOM   7583 C  CB  . ALA D 2 120 ? -51.756 9.746   21.339  1    40.58  ? 116 ALA C CB  1 
ATOM   7584 N  N   . PHE D 2 121 ? -48.999 8.221   21.941  1    43.82  ? 117 PHE C N   1 
ATOM   7585 C  CA  . PHE D 2 121 ? -47.997 7.208   21.64   1    44.32  ? 117 PHE C CA  1 
ATOM   7586 C  C   . PHE D 2 121 ? -47.693 6.382   22.891  1    45.28  ? 117 PHE C C   1 
ATOM   7587 O  O   . PHE D 2 121 ? -47.55  5.171   22.774  1    52.91  ? 117 PHE C O   1 
ATOM   7588 C  CB  . PHE D 2 121 ? -46.698 7.761   21.03   1    42.91  ? 117 PHE C CB  1 
ATOM   7589 C  CG  . PHE D 2 121 ? -45.834 6.7     20.367  1    41.69  ? 117 PHE C CG  1 
ATOM   7590 C  CD1 . PHE D 2 121 ? -44.919 5.955   21.111  1    43.6   ? 117 PHE C CD1 1 
ATOM   7591 C  CD2 . PHE D 2 121 ? -45.972 6.401   19.006  1    42.47  ? 117 PHE C CD2 1 
ATOM   7592 C  CE1 . PHE D 2 121 ? -44.147 4.944   20.513  1    43.05  ? 117 PHE C CE1 1 
ATOM   7593 C  CE2 . PHE D 2 121 ? -45.213 5.386   18.414  1    43.08  ? 117 PHE C CE2 1 
ATOM   7594 C  CZ  . PHE D 2 121 ? -44.298 4.657   19.169  1    43.12  ? 117 PHE C CZ  1 
ATOM   7595 N  N   . CYS D 2 122 ? -47.56  7.02    24.068  1    41.17  ? 118 CYS C N   1 
ATOM   7596 C  CA  . CYS D 2 122 ? -47.344 6.28    25.306  1    39.16  ? 118 CYS C CA  1 
ATOM   7597 C  C   . CYS D 2 122 ? -48.51  5.338   25.567  1    42.41  ? 118 CYS C C   1 
ATOM   7598 O  O   . CYS D 2 122 ? -48.306 4.132   25.727  1    41.7   ? 118 CYS C O   1 
ATOM   7599 C  CB  . CYS D 2 122 ? -47.202 7.182   26.521  1    37.17  ? 118 CYS C CB  1 
ATOM   7600 S  SG  . CYS D 2 122 ? -45.717 8.214   26.411  1    42.19  ? 118 CYS C SG  1 
ATOM   7601 N  N   . HIS D 2 123 ? -49.727 5.911   25.542  1    42.54  ? 119 HIS C N   1 
ATOM   7602 C  CA  . HIS D 2 123 ? -50.951 5.201   25.886  1    41.1   ? 119 HIS C CA  1 
ATOM   7603 C  C   . HIS D 2 123 ? -51.165 3.982   24.986  1    41.31  ? 119 HIS C C   1 
ATOM   7604 O  O   . HIS D 2 123 ? -51.489 2.914   25.505  1    41.29  ? 119 HIS C O   1 
ATOM   7605 C  CB  . HIS D 2 123 ? -52.14  6.162   25.994  1    41.46  ? 119 HIS C CB  1 
ATOM   7606 C  CG  . HIS D 2 123 ? -52.004 7.126   27.122  1    43.55  ? 119 HIS C CG  1 
ATOM   7607 N  ND1 . HIS D 2 123 ? -52.826 8.222   27.278  1    42.46  ? 119 HIS C ND1 1 
ATOM   7608 C  CD2 . HIS D 2 123 ? -51.145 7.148   28.163  1    41.68  ? 119 HIS C CD2 1 
ATOM   7609 C  CE1 . HIS D 2 123 ? -52.458 8.874   28.376  1    44.62  ? 119 HIS C CE1 1 
ATOM   7610 N  NE2 . HIS D 2 123 ? -51.438 8.246   28.924  1    42.54  ? 119 HIS C NE2 1 
ATOM   7611 N  N   . SER D 2 124 ? -51.016 4.167   23.656  1    40.88  ? 120 SER C N   1 
ATOM   7612 C  CA  . SER D 2 124 ? -50.989 3.123   22.633  1    41.64  ? 120 SER C CA  1 
ATOM   7613 C  C   . SER D 2 124 ? -49.976 2.018   22.928  1    43.8   ? 120 SER C C   1 
ATOM   7614 O  O   . SER D 2 124 ? -50.09  0.937   22.346  1    41.45  ? 120 SER C O   1 
ATOM   7615 C  CB  . SER D 2 124 ? -50.63  3.703   21.318  1    41.91  ? 120 SER C CB  1 
ATOM   7616 O  OG  . SER D 2 124 ? -51.611 4.646   20.921  1    52.35  ? 120 SER C OG  1 
ATOM   7617 N  N   . HIS D 2 125 ? -48.936 2.343   23.729  1    44.71  ? 121 HIS C N   1 
ATOM   7618 C  CA  . HIS D 2 125 ? -47.838 1.433   24.047  1    44.76  ? 121 HIS C CA  1 
ATOM   7619 C  C   . HIS D 2 125 ? -47.886 1.055   25.531  1    45     ? 121 HIS C C   1 
ATOM   7620 O  O   . HIS D 2 125 ? -46.879 0.673   26.122  1    42.93  ? 121 HIS C O   1 
ATOM   7621 C  CB  . HIS D 2 125 ? -46.512 2.011   23.544  1    42.32  ? 121 HIS C CB  1 
ATOM   7622 C  CG  . HIS D 2 125 ? -46.43  2.084   22.052  1    46.89  ? 121 HIS C CG  1 
ATOM   7623 N  ND1 . HIS D 2 125 ? -47.161 2.975   21.286  1    49.35  ? 121 HIS C ND1 1 
ATOM   7624 C  CD2 . HIS D 2 125 ? -45.732 1.351   21.175  1    48.91  ? 121 HIS C CD2 1 
ATOM   7625 C  CE1 . HIS D 2 125 ? -46.885 2.797   19.996  1    48.53  ? 121 HIS C CE1 1 
ATOM   7626 N  NE2 . HIS D 2 125 ? -46.022 1.811   19.906  1    49.74  ? 121 HIS C NE2 1 
ATOM   7627 N  N   . ARG D 2 126 ? -49.08  1.121   26.123  1    45.73  ? 122 ARG C N   1 
ATOM   7628 C  CA  . ARG D 2 126 ? -49.321 0.662   27.525  1    44.75  ? 122 ARG C CA  1 
ATOM   7629 C  C   . ARG D 2 126 ? -48.407 1.363   28.558  1    44.62  ? 122 ARG C C   1 
ATOM   7630 O  O   . ARG D 2 126 ? -48.119 0.762   29.594  1    46.72  ? 122 ARG C O   1 
ATOM   7631 C  CB  . ARG D 2 126 ? -49.339 -0.876  27.495  1    42.13  ? 122 ARG C CB  1 
ATOM   7632 C  CG  . ARG D 2 126 ? -48.225 -1.719  28.096  1    41.35  ? 122 ARG C CG  1 
ATOM   7633 C  CD  . ARG D 2 126 ? -47.441 -2.467  27.057  1    47.32  ? 122 ARG C CD  1 
ATOM   7634 N  NE  . ARG D 2 126 ? -46.123 -2.838  27.578  1    55.63  ? 122 ARG C NE  1 
ATOM   7635 C  CZ  . ARG D 2 126 ? -45     -2.539  26.955  1    51.28  ? 122 ARG C CZ  1 
ATOM   7636 N  NH1 . ARG D 2 126 ? -44.712 -1.279  26.697  1    49.97  ? 122 ARG C NH1 1 
ATOM   7637 N  NH2 . ARG D 2 126 ? -44.183 -3.501  26.576  1    44.98  ? 122 ARG C NH2 1 
ATOM   7638 N  N   . VAL D 2 127 ? -48.074 2.633   28.35   1    41.18  ? 123 VAL C N   1 
ATOM   7639 C  CA  . VAL D 2 127 ? -47.275 3.341   29.351  1    40.03  ? 123 VAL C CA  1 
ATOM   7640 C  C   . VAL D 2 127 ? -48.063 4.555   29.826  1    39.04  ? 123 VAL C C   1 
ATOM   7641 O  O   . VAL D 2 127 ? -48.525 5.336   28.997  1    39.41  ? 123 VAL C O   1 
ATOM   7642 C  CB  . VAL D 2 127 ? -45.897 3.778   28.791  1    37.55  ? 123 VAL C CB  1 
ATOM   7643 C  CG1 . VAL D 2 127 ? -45.185 4.798   29.683  1    33.44  ? 123 VAL C CG1 1 
ATOM   7644 C  CG2 . VAL D 2 127 ? -44.998 2.585   28.477  1    34.22  ? 123 VAL C CG2 1 
ATOM   7645 N  N   . LEU D 2 128 ? -48.215 4.671   31.152  1    40.58  ? 124 LEU C N   1 
ATOM   7646 C  CA  . LEU D 2 128 ? -48.659 5.88    31.841  1    40.32  ? 124 LEU C CA  1 
ATOM   7647 C  C   . LEU D 2 128 ? -47.429 6.699   32.217  1    41.29  ? 124 LEU C C   1 
ATOM   7648 O  O   . LEU D 2 128 ? -46.451 6.131   32.729  1    39.78  ? 124 LEU C O   1 
ATOM   7649 C  CB  . LEU D 2 128 ? -49.432 5.541   33.116  1    40.38  ? 124 LEU C CB  1 
ATOM   7650 C  CG  . LEU D 2 128 ? -50.717 4.707   33.017  1    41.48  ? 124 LEU C CG  1 
ATOM   7651 C  CD1 . LEU D 2 128 ? -51.281 4.446   34.426  1    37.91  ? 124 LEU C CD1 1 
ATOM   7652 C  CD2 . LEU D 2 128 ? -51.757 5.383   32.14   1    39.39  ? 124 LEU C CD2 1 
ATOM   7653 N  N   . HIS D 2 129 ? -47.491 8.025   31.983  1    39.44  ? 125 HIS C N   1 
ATOM   7654 C  CA  . HIS D 2 129 ? -46.37  8.895   32.299  1    38.47  ? 125 HIS C CA  1 
ATOM   7655 C  C   . HIS D 2 129 ? -46.412 9.233   33.792  1    42.7   ? 125 HIS C C   1 
ATOM   7656 O  O   . HIS D 2 129 ? -45.405 9.108   34.487  1    43.73  ? 125 HIS C O   1 
ATOM   7657 C  CB  . HIS D 2 129 ? -46.288 10.098  31.348  1    38.73  ? 125 HIS C CB  1 
ATOM   7658 C  CG  . HIS D 2 129 ? -45.124 11.004  31.633  1    42.83  ? 125 HIS C CG  1 
ATOM   7659 N  ND1 . HIS D 2 129 ? -44.996 11.766  32.79   1    41.4   ? 125 HIS C ND1 1 
ATOM   7660 C  CD2 . HIS D 2 129 ? -43.994 11.214  30.919  1    40.2   ? 125 HIS C CD2 1 
ATOM   7661 C  CE1 . HIS D 2 129 ? -43.837 12.423  32.762  1    40.54  ? 125 HIS C CE1 1 
ATOM   7662 N  NE2 . HIS D 2 129 ? -43.22  12.116  31.627  1    44.06  ? 125 HIS C NE2 1 
ATOM   7663 N  N   . ARG D 2 130 ? -47.576 9.703   34.267  1    42.1   ? 126 ARG C N   1 
ATOM   7664 C  CA  . ARG D 2 130 ? -47.85  9.93    35.679  1    40.55  ? 126 ARG C CA  1 
ATOM   7665 C  C   . ARG D 2 130 ? -47.013 11.064  36.28   1    41.33  ? 126 ARG C C   1 
ATOM   7666 O  O   . ARG D 2 130 ? -46.99  11.204  37.499  1    41.36  ? 126 ARG C O   1 
ATOM   7667 C  CB  . ARG D 2 130 ? -47.637 8.655   36.5    1    36.75  ? 126 ARG C CB  1 
ATOM   7668 C  CG  . ARG D 2 130 ? -48.473 7.482   36.018  1    34.55  ? 126 ARG C CG  1 
ATOM   7669 C  CD  . ARG D 2 130 ? -48.538 6.423   37.074  1    35.57  ? 126 ARG C CD  1 
ATOM   7670 N  NE  . ARG D 2 130 ? -47.221 5.933   37.495  1    37.35  ? 126 ARG C NE  1 
ATOM   7671 C  CZ  . ARG D 2 130 ? -47.042 4.944   38.372  1    38.22  ? 126 ARG C CZ  1 
ATOM   7672 N  NH1 . ARG D 2 130 ? -48.089 4.352   38.949  1    39.28  ? 126 ARG C NH1 1 
ATOM   7673 N  NH2 . ARG D 2 130 ? -45.814 4.561   38.67   1    36.2   ? 126 ARG C NH2 1 
ATOM   7674 N  N   . ASP D 2 131 ? -46.346 11.891  35.464  1    41.39  ? 127 ASP C N   1 
ATOM   7675 C  CA  . ASP D 2 131 ? -45.658 13.046  36.034  1    42.21  ? 127 ASP C CA  1 
ATOM   7676 C  C   . ASP D 2 131 ? -45.605 14.195  35.028  1    41.88  ? 127 ASP C C   1 
ATOM   7677 O  O   . ASP D 2 131 ? -44.602 14.896  34.889  1    41.18  ? 127 ASP C O   1 
ATOM   7678 C  CB  . ASP D 2 131 ? -44.291 12.711  36.61   1    38.81  ? 127 ASP C CB  1 
ATOM   7679 C  CG  . ASP D 2 131 ? -43.797 13.689  37.674  1    43.88  ? 127 ASP C CG  1 
ATOM   7680 O  OD1 . ASP D 2 131 ? -44.63  14.485  38.206  1    43.43  ? 127 ASP C OD1 1 
ATOM   7681 O  OD2 . ASP D 2 131 ? -42.569 13.682  37.948  1    46.11  ? 127 ASP C OD2 1 
ATOM   7682 N  N   . LEU D 2 132 ? -46.716 14.434  34.347  1    42.32  ? 128 LEU C N   1 
ATOM   7683 C  CA  . LEU D 2 132 ? -46.656 15.473  33.342  1    44.29  ? 128 LEU C CA  1 
ATOM   7684 C  C   . LEU D 2 132 ? -46.759 16.812  34.06   1    44.85  ? 128 LEU C C   1 
ATOM   7685 O  O   . LEU D 2 132 ? -47.69  17.036  34.811  1    51.48  ? 128 LEU C O   1 
ATOM   7686 C  CB  . LEU D 2 132 ? -47.754 15.222  32.314  1    38.66  ? 128 LEU C CB  1 
ATOM   7687 C  CG  . LEU D 2 132 ? -47.526 13.984  31.441  1    38.73  ? 128 LEU C CG  1 
ATOM   7688 C  CD1 . LEU D 2 132 ? -48.778 13.681  30.636  1    39.99  ? 128 LEU C CD1 1 
ATOM   7689 C  CD2 . LEU D 2 132 ? -46.304 14.113  30.527  1    35.55  ? 128 LEU C CD2 1 
ATOM   7690 N  N   . LYS D 2 133 ? -45.743 17.646  33.885  1    41.68  ? 129 LYS C N   1 
ATOM   7691 C  CA  . LYS D 2 133 ? -45.749 19.024  34.34   1    42.44  ? 129 LYS C CA  1 
ATOM   7692 C  C   . LYS D 2 133 ? -44.717 19.808  33.537  1    43.48  ? 129 LYS C C   1 
ATOM   7693 O  O   . LYS D 2 133 ? -43.861 19.212  32.883  1    43.41  ? 129 LYS C O   1 
ATOM   7694 C  CB  . LYS D 2 133 ? -45.381 19.091  35.819  1    43.04  ? 129 LYS C CB  1 
ATOM   7695 C  CG  . LYS D 2 133 ? -44.151 18.29   36.143  1    46.11  ? 129 LYS C CG  1 
ATOM   7696 C  CD  . LYS D 2 133 ? -43.744 18.48   37.599  1    45.94  ? 129 LYS C CD  1 
ATOM   7697 C  CE  . LYS D 2 133 ? -42.542 17.656  37.929  1    45.98  ? 129 LYS C CE  1 
ATOM   7698 N  NZ  . LYS D 2 133 ? -41.977 18.197  39.168  1    51.83  ? 129 LYS C NZ  1 
ATOM   7699 N  N   . PRO D 2 134 ? -44.741 21.161  33.55   1    44.9   ? 130 PRO C N   1 
ATOM   7700 C  CA  . PRO D 2 134 ? -43.931 21.922  32.606  1    41.41  ? 130 PRO C CA  1 
ATOM   7701 C  C   . PRO D 2 134 ? -42.458 21.539  32.704  1    40.25  ? 130 PRO C C   1 
ATOM   7702 O  O   . PRO D 2 134 ? -41.766 21.47   31.689  1    41.1   ? 130 PRO C O   1 
ATOM   7703 C  CB  . PRO D 2 134 ? -44.215 23.374  32.976  1    43.46  ? 130 PRO C CB  1 
ATOM   7704 C  CG  . PRO D 2 134 ? -45.556 23.321  33.66   1    44.61  ? 130 PRO C CG  1 
ATOM   7705 C  CD  . PRO D 2 134 ? -45.522 22.025  34.456  1    44.71  ? 130 PRO C CD  1 
ATOM   7706 N  N   . GLN D 2 135 ? -42.004 21.222  33.92   1    42.21  ? 131 GLN C N   1 
ATOM   7707 C  CA  . GLN D 2 135 ? -40.591 20.965  34.184  1    42.39  ? 131 GLN C CA  1 
ATOM   7708 C  C   . GLN D 2 135 ? -40.139 19.663  33.541  1    41.09  ? 131 GLN C C   1 
ATOM   7709 O  O   . GLN D 2 135 ? -38.94  19.457  33.459  1    43.77  ? 131 GLN C O   1 
ATOM   7710 C  CB  . GLN D 2 135 ? -40.233 20.791  35.654  1    42.26  ? 131 GLN C CB  1 
ATOM   7711 C  CG  . GLN D 2 135 ? -40.455 22.04   36.502  1    52.1   ? 131 GLN C CG  1 
ATOM   7712 C  CD  . GLN D 2 135 ? -41.893 22.353  36.889  1    55.41  ? 131 GLN C CD  1 
ATOM   7713 O  OE1 . GLN D 2 135 ? -42.881 21.736  36.453  1    55.8   ? 131 GLN C OE1 1 
ATOM   7714 N  NE2 . GLN D 2 135 ? -42.014 23.389  37.703  1    54.56  ? 131 GLN C NE2 1 
ATOM   7715 N  N   . ASN D 2 136 ? -41.084 18.801  33.133  1    39.12  ? 132 ASN C N   1 
ATOM   7716 C  CA  . ASN D 2 136 ? -40.774 17.52   32.507  1    36.53  ? 132 ASN C CA  1 
ATOM   7717 C  C   . ASN D 2 136 ? -41.044 17.554  31.003  1    36.2   ? 132 ASN C C   1 
ATOM   7718 O  O   . ASN D 2 136 ? -41.072 16.505  30.368  1    38.92  ? 132 ASN C O   1 
ATOM   7719 C  CB  . ASN D 2 136 ? -41.514 16.363  33.179  1    36.42  ? 132 ASN C CB  1 
ATOM   7720 C  CG  . ASN D 2 136 ? -41.069 16.138  34.609  1    38.85  ? 132 ASN C CG  1 
ATOM   7721 O  OD1 . ASN D 2 136 ? -40.069 16.708  35.071  1    39.32  ? 132 ASN C OD1 1 
ATOM   7722 N  ND2 . ASN D 2 136 ? -41.827 15.346  35.347  1    36.67  ? 132 ASN C ND2 1 
ATOM   7723 N  N   . LEU D 2 137 ? -41.298 18.741  30.436  1    33.97  ? 133 LEU C N   1 
ATOM   7724 C  CA  . LEU D 2 137 ? -41.498 18.869  29.011  1    31.61  ? 133 LEU C CA  1 
ATOM   7725 C  C   . LEU D 2 137 ? -40.377 19.744  28.46   1    35.88  ? 133 LEU C C   1 
ATOM   7726 O  O   . LEU D 2 137 ? -40.181 20.876  28.931  1    35     ? 133 LEU C O   1 
ATOM   7727 C  CB  . LEU D 2 137 ? -42.875 19.452  28.744  1    30.3   ? 133 LEU C CB  1 
ATOM   7728 C  CG  . LEU D 2 137 ? -44.035 18.726  29.43   1    31.89  ? 133 LEU C CG  1 
ATOM   7729 C  CD1 . LEU D 2 137 ? -45.38  19.411  29.169  1    32.24  ? 133 LEU C CD1 1 
ATOM   7730 C  CD2 . LEU D 2 137 ? -44.146 17.274  28.974  1    29.42  ? 133 LEU C CD2 1 
ATOM   7731 N  N   . LEU D 2 138 ? -39.673 19.2    27.448  1    36.48  ? 134 LEU C N   1 
ATOM   7732 C  CA  . LEU D 2 138 ? -38.46  19.8    26.905  1    38.14  ? 134 LEU C CA  1 
ATOM   7733 C  C   . LEU D 2 138 ? -38.742 20.327  25.499  1    40.14  ? 134 LEU C C   1 
ATOM   7734 O  O   . LEU D 2 138 ? -39.322 19.613  24.681  1    47.31  ? 134 LEU C O   1 
ATOM   7735 C  CB  . LEU D 2 138 ? -37.369 18.731  26.91   1    37.72  ? 134 LEU C CB  1 
ATOM   7736 C  CG  . LEU D 2 138 ? -37.083 18.104  28.282  1    40.4   ? 134 LEU C CG  1 
ATOM   7737 C  CD1 . LEU D 2 138 ? -35.908 17.135  28.241  1    40.13  ? 134 LEU C CD1 1 
ATOM   7738 C  CD2 . LEU D 2 138 ? -36.797 19.183  29.302  1    35.45  ? 134 LEU C CD2 1 
ATOM   7739 N  N   . ILE D 2 139 ? -38.346 21.576  25.238  1    37.04  ? 135 ILE C N   1 
ATOM   7740 C  CA  . ILE D 2 139 ? -38.473 22.199  23.931  1    39.32  ? 135 ILE C CA  1 
ATOM   7741 C  C   . ILE D 2 139 ? -37.085 22.41   23.321  1    41.87  ? 135 ILE C C   1 
ATOM   7742 O  O   . ILE D 2 139 ? -36.097 22.534  24.039  1    40.4   ? 135 ILE C O   1 
ATOM   7743 C  CB  . ILE D 2 139 ? -39.158 23.565  24.063  1    37.85  ? 135 ILE C CB  1 
ATOM   7744 C  CG1 . ILE D 2 139 ? -38.304 24.532  24.857  1    38.61  ? 135 ILE C CG1 1 
ATOM   7745 C  CG2 . ILE D 2 139 ? -40.527 23.386  24.691  1    39.74  ? 135 ILE C CG2 1 
ATOM   7746 C  CD1 . ILE D 2 139 ? -38.647 25.982  24.617  1    42.45  ? 135 ILE C CD1 1 
ATOM   7747 N  N   . ASN D 2 140 ? -37.033 22.502  21.987  1    44.22  ? 136 ASN C N   1 
ATOM   7748 C  CA  . ASN D 2 140 ? -35.819 22.884  21.268  1    47.84  ? 136 ASN C CA  1 
ATOM   7749 C  C   . ASN D 2 140 ? -36.034 24.243  20.599  1    50.85  ? 136 ASN C C   1 
ATOM   7750 O  O   . ASN D 2 140 ? -37.115 24.841  20.697  1    51.12  ? 136 ASN C O   1 
ATOM   7751 C  CB  . ASN D 2 140 ? -35.327 21.796  20.304  1    45.25  ? 136 ASN C CB  1 
ATOM   7752 C  CG  . ASN D 2 140 ? -36.253 21.501  19.132  1    47.12  ? 136 ASN C CG  1 
ATOM   7753 O  OD1 . ASN D 2 140 ? -37.185 22.252  18.791  1    44.46  ? 136 ASN C OD1 1 
ATOM   7754 N  ND2 . ASN D 2 140 ? -36     20.384  18.475  1    47.12  ? 136 ASN C ND2 1 
ATOM   7755 N  N   . THR D 2 141 ? -35.002 24.691  19.888  1    52.05  ? 137 THR C N   1 
ATOM   7756 C  CA  . THR D 2 141 ? -35.024 26.005  19.269  1    60.05  ? 137 THR C CA  1 
ATOM   7757 C  C   . THR D 2 141 ? -35.816 25.977  17.962  1    62.19  ? 137 THR C C   1 
ATOM   7758 O  O   . THR D 2 141 ? -35.913 27.011  17.297  1    64.07  ? 137 THR C O   1 
ATOM   7759 C  CB  . THR D 2 141 ? -33.601 26.517  19.018  1    61.23  ? 137 THR C CB  1 
ATOM   7760 O  OG1 . THR D 2 141 ? -33.022 25.722  17.984  1    64.71  ? 137 THR C OG1 1 
ATOM   7761 C  CG2 . THR D 2 141 ? -32.709 26.431  20.238  1    58.93  ? 137 THR C CG2 1 
ATOM   7762 N  N   . GLU D 2 142 ? -36.34  24.805  17.575  1    57.85  ? 138 GLU C N   1 
ATOM   7763 C  CA  . GLU D 2 142 ? -36.93  24.654  16.251  1    62.9   ? 138 GLU C CA  1 
ATOM   7764 C  C   . GLU D 2 142 ? -38.449 24.477  16.284  1    58.57  ? 138 GLU C C   1 
ATOM   7765 O  O   . GLU D 2 142 ? -39.042 24.25   15.24   1    59.42  ? 138 GLU C O   1 
ATOM   7766 C  CB  . GLU D 2 142 ? -36.266 23.508  15.489  1    65.47  ? 138 GLU C CB  1 
ATOM   7767 C  CG  . GLU D 2 142 ? -34.776 23.75   15.269  1    84.13  ? 138 GLU C CG  1 
ATOM   7768 C  CD  . GLU D 2 142 ? -34.218 23.238  13.95   1    100.43 ? 138 GLU C CD  1 
ATOM   7769 O  OE1 . GLU D 2 142 ? -34.564 22.102  13.544  1    101.99 ? 138 GLU C OE1 1 
ATOM   7770 O  OE2 . GLU D 2 142 ? -33.422 23.987  13.333  1    104.56 ? 138 GLU C OE2 1 
ATOM   7771 N  N   . GLY D 2 143 ? -39.07  24.518  17.47   1    51.11  ? 139 GLY C N   1 
ATOM   7772 C  CA  . GLY D 2 143 ? -40.515 24.478  17.558  1    47.63  ? 139 GLY C CA  1 
ATOM   7773 C  C   . GLY D 2 143 ? -41.056 23.135  18.042  1    46.36  ? 139 GLY C C   1 
ATOM   7774 O  O   . GLY D 2 143 ? -42.269 22.929  18.036  1    47.13  ? 139 GLY C O   1 
ATOM   7775 N  N   . ALA D 2 144 ? -40.162 22.233  18.46   1    43.96  ? 140 ALA C N   1 
ATOM   7776 C  CA  . ALA D 2 144 ? -40.579 20.911  18.898  1    43.24  ? 140 ALA C CA  1 
ATOM   7777 C  C   . ALA D 2 144 ? -40.736 20.906  20.422  1    42.29  ? 140 ALA C C   1 
ATOM   7778 O  O   . ALA D 2 144 ? -40.075 21.69   21.1    1    41.24  ? 140 ALA C O   1 
ATOM   7779 C  CB  . ALA D 2 144 ? -39.559 19.888  18.426  1    40.2   ? 140 ALA C CB  1 
ATOM   7780 N  N   . ILE D 2 145 ? -41.602 20.022  20.942  1    40.42  ? 141 ILE C N   1 
ATOM   7781 C  CA  . ILE D 2 145 ? -41.708 19.782  22.377  1    43.06  ? 141 ILE C CA  1 
ATOM   7782 C  C   . ILE D 2 145 ? -41.81  18.273  22.611  1    42.8   ? 141 ILE C C   1 
ATOM   7783 O  O   . ILE D 2 145 ? -42.398 17.572  21.797  1    45.51  ? 141 ILE C O   1 
ATOM   7784 C  CB  . ILE D 2 145 ? -42.902 20.549  23.002  1    44.71  ? 141 ILE C CB  1 
ATOM   7785 C  CG1 . ILE D 2 145 ? -42.805 20.616  24.547  1    41.58  ? 141 ILE C CG1 1 
ATOM   7786 C  CG2 . ILE D 2 145 ? -44.237 19.975  22.516  1    42.29  ? 141 ILE C CG2 1 
ATOM   7787 C  CD1 . ILE D 2 145 ? -43.908 21.385  25.251  1    40.8   ? 141 ILE C CD1 1 
ATOM   7788 N  N   . LYS D 2 146 ? -41.271 17.788  23.736  1    40.58  ? 142 LYS C N   1 
ATOM   7789 C  CA  . LYS D 2 146 ? -41.169 16.357  23.981  1    38.57  ? 142 LYS C CA  1 
ATOM   7790 C  C   . LYS D 2 146 ? -41.408 16.02   25.454  1    37.94  ? 142 LYS C C   1 
ATOM   7791 O  O   . LYS D 2 146 ? -40.937 16.726  26.341  1    40.74  ? 142 LYS C O   1 
ATOM   7792 C  CB  . LYS D 2 146 ? -39.777 15.856  23.59   1    38     ? 142 LYS C CB  1 
ATOM   7793 C  CG  . LYS D 2 146 ? -39.357 16.212  22.181  1    38.47  ? 142 LYS C CG  1 
ATOM   7794 C  CD  . LYS D 2 146 ? -38.216 15.337  21.689  1    37.58  ? 142 LYS C CD  1 
ATOM   7795 C  CE  . LYS D 2 146 ? -37.573 15.857  20.42   1    40.68  ? 142 LYS C CE  1 
ATOM   7796 N  NZ  . LYS D 2 146 ? -36.793 14.8    19.754  1    41.71  ? 142 LYS C NZ  1 
ATOM   7797 N  N   . LEU D 2 147 ? -42.147 14.932  25.702  1    34.33  ? 143 LEU C N   1 
ATOM   7798 C  CA  . LEU D 2 147 ? -42.307 14.405  27.037  1    33.61  ? 143 LEU C CA  1 
ATOM   7799 C  C   . LEU D 2 147 ? -40.942 13.944  27.527  1    36.29  ? 143 LEU C C   1 
ATOM   7800 O  O   . LEU D 2 147 ? -40.257 13.236  26.815  1    40.83  ? 143 LEU C O   1 
ATOM   7801 C  CB  . LEU D 2 147 ? -43.249 13.208  27.012  1    32.74  ? 143 LEU C CB  1 
ATOM   7802 C  CG  . LEU D 2 147 ? -44.62  13.359  26.341  1    36.68  ? 143 LEU C CG  1 
ATOM   7803 C  CD1 . LEU D 2 147 ? -45.509 12.207  26.76   1    37.39  ? 143 LEU C CD1 1 
ATOM   7804 C  CD2 . LEU D 2 147 ? -45.338 14.635  26.622  1    36.38  ? 143 LEU C CD2 1 
ATOM   7805 N  N   . ALA D 2 148 ? -40.585 14.252  28.773  1    36.23  ? 144 ALA C N   1 
ATOM   7806 C  CA  . ALA D 2 148 ? -39.328 13.773  29.344  1    39.24  ? 144 ALA C CA  1 
ATOM   7807 C  C   . ALA D 2 148 ? -39.532 13.288  30.784  1    40.8   ? 144 ALA C C   1 
ATOM   7808 O  O   . ALA D 2 148 ? -40.634 13.37   31.314  1    42.52  ? 144 ALA C O   1 
ATOM   7809 C  CB  . ALA D 2 148 ? -38.289 14.875  29.262  1    35.29  ? 144 ALA C CB  1 
ATOM   7810 N  N   . ASP D 2 149 ? -38.457 12.782  31.401  1    43.64  ? 145 ASP C N   1 
ATOM   7811 C  CA  . ASP D 2 149 ? -38.437 12.275  32.767  1    47.1   ? 145 ASP C CA  1 
ATOM   7812 C  C   . ASP D 2 149 ? -39.491 11.184  32.941  1    44.89  ? 145 ASP C C   1 
ATOM   7813 O  O   . ASP D 2 149 ? -40.566 11.411  33.49   1    43.75  ? 145 ASP C O   1 
ATOM   7814 C  CB  . ASP D 2 149 ? -38.454 13.382  33.813  1    50.2   ? 145 ASP C CB  1 
ATOM   7815 C  CG  . ASP D 2 149 ? -38.021 12.924  35.203  1    65.69  ? 145 ASP C CG  1 
ATOM   7816 O  OD1 . ASP D 2 149 ? -37.916 11.677  35.434  1    64.5   ? 145 ASP C OD1 1 
ATOM   7817 O  OD2 . ASP D 2 149 ? -37.777 13.811  36.055  1    70.99  ? 145 ASP C OD2 1 
ATOM   7818 N  N   . PHE D 2 150 ? -39.175 9.991   32.438  1    45.59  ? 146 PHE C N   1 
ATOM   7819 C  CA  . PHE D 2 150 ? -40.063 8.85    32.585  1    40.07  ? 146 PHE C CA  1 
ATOM   7820 C  C   . PHE D 2 150 ? -39.756 8.119   33.883  1    41.72  ? 146 PHE C C   1 
ATOM   7821 O  O   . PHE D 2 150 ? -40.024 6.934   34.008  1    44.1   ? 146 PHE C O   1 
ATOM   7822 C  CB  . PHE D 2 150 ? -39.878 7.935   31.38   1    37.87  ? 146 PHE C CB  1 
ATOM   7823 C  CG  . PHE D 2 150 ? -40.709 8.435   30.222  1    35.93  ? 146 PHE C CG  1 
ATOM   7824 C  CD1 . PHE D 2 150 ? -40.323 9.567   29.524  1    33.67  ? 146 PHE C CD1 1 
ATOM   7825 C  CD2 . PHE D 2 150 ? -41.876 7.767   29.853  1    35.83  ? 146 PHE C CD2 1 
ATOM   7826 C  CE1 . PHE D 2 150 ? -41.116 10.055  28.496  1    35.2   ? 146 PHE C CE1 1 
ATOM   7827 C  CE2 . PHE D 2 150 ? -42.658 8.251   28.816  1    37.83  ? 146 PHE C CE2 1 
ATOM   7828 C  CZ  . PHE D 2 150 ? -42.282 9.402   28.137  1    35.86  ? 146 PHE C CZ  1 
ATOM   7829 N  N   . GLY D 2 151 ? -39.21  8.846   34.856  1    47.69  ? 147 GLY C N   1 
ATOM   7830 C  CA  . GLY D 2 151 ? -38.786 8.243   36.107  1    51.17  ? 147 GLY C CA  1 
ATOM   7831 C  C   . GLY D 2 151 ? -39.942 7.583   36.849  1    51.83  ? 147 GLY C C   1 
ATOM   7832 O  O   . GLY D 2 151 ? -39.731 6.594   37.543  1    53.58  ? 147 GLY C O   1 
ATOM   7833 N  N   . LEU D 2 152 ? -41.14  8.183   36.76   1    53.46  ? 148 LEU C N   1 
ATOM   7834 C  CA  . LEU D 2 152 ? -42.336 7.736   37.524  1    50.41  ? 148 LEU C CA  1 
ATOM   7835 C  C   . LEU D 2 152 ? -43.358 7.069   36.606  1    51.26  ? 148 LEU C C   1 
ATOM   7836 O  O   . LEU D 2 152 ? -44.518 6.921   37.022  1    52.23  ? 148 LEU C O   1 
ATOM   7837 C  CB  . LEU D 2 152 ? -42.899 9.015   38.129  1    50.36  ? 148 LEU C CB  1 
ATOM   7838 C  CG  . LEU D 2 152 ? -42.03  9.735   39.16   1    60.7   ? 148 LEU C CG  1 
ATOM   7839 C  CD1 . LEU D 2 152 ? -42.683 11.049  39.533  1    54.68  ? 148 LEU C CD1 1 
ATOM   7840 C  CD2 . LEU D 2 152 ? -41.895 8.84    40.378  1    60.06  ? 148 LEU C CD2 1 
ATOM   7841 N  N   . ALA D 2 153 ? -42.955 6.728   35.395  1    46.52  ? 149 ALA C N   1 
ATOM   7842 C  CA  . ALA D 2 153 ? -43.789 6.037   34.431  1    42.88  ? 149 ALA C CA  1 
ATOM   7843 C  C   . ALA D 2 153 ? -44.005 4.593   34.875  1    44.78  ? 149 ALA C C   1 
ATOM   7844 O  O   . ALA D 2 153 ? -43.351 4.102   35.796  1    48.81  ? 149 ALA C O   1 
ATOM   7845 C  CB  . ALA D 2 153 ? -43.12  6.093   33.086  1    38.63  ? 149 ALA C CB  1 
ATOM   7846 N  N   . ARG D 2 154 ? -44.934 3.918   34.19   1    44.93  ? 150 ARG C N   1 
ATOM   7847 C  CA  . ARG D 2 154 ? -45.341 2.569   34.552  1    46.24  ? 150 ARG C CA  1 
ATOM   7848 C  C   . ARG D 2 154 ? -46.019 1.909   33.347  1    42.68  ? 150 ARG C C   1 
ATOM   7849 O  O   . ARG D 2 154 ? -46.875 2.495   32.691  1    43.1   ? 150 ARG C O   1 
ATOM   7850 C  CB  . ARG D 2 154 ? -46.117 2.701   35.868  1    47.26  ? 150 ARG C CB  1 
ATOM   7851 C  CG  . ARG D 2 154 ? -47.232 1.695   36.069  1    54.29  ? 150 ARG C CG  1 
ATOM   7852 C  CD  . ARG D 2 154 ? -46.783 0.392   36.666  1    58.52  ? 150 ARG C CD  1 
ATOM   7853 N  NE  . ARG D 2 154 ? -46.826 0.378   38.135  1    52.13  ? 150 ARG C NE  1 
ATOM   7854 C  CZ  . ARG D 2 154 ? -46.786 -0.76   38.82   1    47.97  ? 150 ARG C CZ  1 
ATOM   7855 N  NH1 . ARG D 2 154 ? -46.821 -0.743  40.144  1    49.98  ? 150 ARG C NH1 1 
ATOM   7856 N  NH2 . ARG D 2 154 ? -46.715 -1.907  38.169  1    42.59  ? 150 ARG C NH2 1 
ATOM   7857 N  N   . ALA D 2 155 ? -45.571 0.705   32.999  1    42.55  ? 151 ALA C N   1 
ATOM   7858 C  CA  . ALA D 2 155 ? -46.243 -0.101  31.989  1    41.48  ? 151 ALA C CA  1 
ATOM   7859 C  C   . ALA D 2 155 ? -47.52  -0.646  32.618  1    45.08  ? 151 ALA C C   1 
ATOM   7860 O  O   . ALA D 2 155 ? -47.45  -1.264  33.683  1    49.56  ? 151 ALA C O   1 
ATOM   7861 C  CB  . ALA D 2 155 ? -45.328 -1.224  31.529  1    37.03  ? 151 ALA C CB  1 
ATOM   7862 N  N   . PHE D 2 156 ? -48.678 -0.392  31.989  1    45.87  ? 152 PHE C N   1 
ATOM   7863 C  CA  . PHE D 2 156 ? -49.945 -0.903  32.517  1    46.71  ? 152 PHE C CA  1 
ATOM   7864 C  C   . PHE D 2 156 ? -50.456 -2.105  31.715  1    46.4   ? 152 PHE C C   1 
ATOM   7865 O  O   . PHE D 2 156 ? -50.042 -2.33   30.578  1    47.12  ? 152 PHE C O   1 
ATOM   7866 C  CB  . PHE D 2 156 ? -50.974 0.225   32.642  1    43.51  ? 152 PHE C CB  1 
ATOM   7867 C  CG  . PHE D 2 156 ? -51.497 0.831   31.35   1    43.04  ? 152 PHE C CG  1 
ATOM   7868 C  CD1 . PHE D 2 156 ? -52.6   0.281   30.691  1    42.35  ? 152 PHE C CD1 1 
ATOM   7869 C  CD2 . PHE D 2 156 ? -50.93  2.001   30.842  1    42.97  ? 152 PHE C CD2 1 
ATOM   7870 C  CE1 . PHE D 2 156 ? -53.111 0.876   29.539  1    42.44  ? 152 PHE C CE1 1 
ATOM   7871 C  CE2 . PHE D 2 156 ? -51.436 2.599   29.688  1    42.96  ? 152 PHE C CE2 1 
ATOM   7872 C  CZ  . PHE D 2 156 ? -52.521 2.027   29.029  1    42.18  ? 152 PHE C CZ  1 
ATOM   7873 N  N   . GLY D 2 157 ? -51.356 -2.884  32.335  1    46.53  ? 153 GLY C N   1 
ATOM   7874 C  CA  . GLY D 2 157 ? -52.1   -3.934  31.652  1    46.06  ? 153 GLY C CA  1 
ATOM   7875 C  C   . GLY D 2 157 ? -53.553 -3.495  31.43   1    50.06  ? 153 GLY C C   1 
ATOM   7876 O  O   . GLY D 2 157 ? -53.93  -2.385  31.848  1    49.15  ? 153 GLY C O   1 
ATOM   7877 N  N   . VAL D 2 158 ? -54.367 -4.361  30.786  1    48.11  ? 154 VAL C N   1 
ATOM   7878 C  CA  . VAL D 2 158 ? -55.738 -4.024  30.432  1    47.56  ? 154 VAL C CA  1 
ATOM   7879 C  C   . VAL D 2 158 ? -56.669 -5.105  30.968  1    51.35  ? 154 VAL C C   1 
ATOM   7880 O  O   . VAL D 2 158 ? -56.526 -6.263  30.578  1    53.95  ? 154 VAL C O   1 
ATOM   7881 C  CB  . VAL D 2 158 ? -55.904 -3.86   28.911  1    48.47  ? 154 VAL C CB  1 
ATOM   7882 C  CG1 . VAL D 2 158 ? -57.319 -3.435  28.547  1    51.09  ? 154 VAL C CG1 1 
ATOM   7883 C  CG2 . VAL D 2 158 ? -54.908 -2.875  28.315  1    47.65  ? 154 VAL C CG2 1 
ATOM   7884 N  N   . PRO D 2 159 ? -57.636 -4.807  31.884  1    54.46  ? 155 PRO C N   1 
ATOM   7885 C  CA  . PRO D 2 159 ? -57.827 -3.47   32.479  1    51.2   ? 155 PRO C CA  1 
ATOM   7886 C  C   . PRO D 2 159 ? -56.729 -3.104  33.473  1    50.12  ? 155 PRO C C   1 
ATOM   7887 O  O   . PRO D 2 159 ? -55.963 -3.974  33.9    1    51.39  ? 155 PRO C O   1 
ATOM   7888 C  CB  . PRO D 2 159 ? -59.165 -3.629  33.245  1    51.89  ? 155 PRO C CB  1 
ATOM   7889 C  CG  . PRO D 2 159 ? -59.188 -5.097  33.643  1    52.48  ? 155 PRO C CG  1 
ATOM   7890 C  CD  . PRO D 2 159 ? -58.6   -5.799  32.422  1    53.36  ? 155 PRO C CD  1 
ATOM   7891 N  N   . VAL D 2 160 ? -56.679 -1.825  33.867  1    48.78  ? 156 VAL C N   1 
ATOM   7892 C  CA  . VAL D 2 160 ? -55.653 -1.396  34.806  1    47.17  ? 156 VAL C CA  1 
ATOM   7893 C  C   . VAL D 2 160 ? -55.905 -2.111  36.119  1    49.12  ? 156 VAL C C   1 
ATOM   7894 O  O   . VAL D 2 160 ? -57.035 -2.531  36.361  1    50.57  ? 156 VAL C O   1 
ATOM   7895 C  CB  . VAL D 2 160 ? -55.579 0.123   35.003  1    43.06  ? 156 VAL C CB  1 
ATOM   7896 C  CG1 . VAL D 2 160 ? -55.153 0.804   33.713  1    43.94  ? 156 VAL C CG1 1 
ATOM   7897 C  CG2 . VAL D 2 160 ? -56.884 0.697   35.503  1    42.54  ? 156 VAL C CG2 1 
ATOM   7898 N  N   . ARG D 2 161 ? -54.859 -2.153  36.935  1    51.22  ? 157 ARG C N   1 
ATOM   7899 C  CA  . ARG D 2 161 ? -54.97  -2.699  38.3    1    56.5   ? 157 ARG C CA  1 
ATOM   7900 C  C   . ARG D 2 161 ? -54.511 -1.568  39.225  1    53.95  ? 157 ARG C C   1 
ATOM   7901 O  O   . ARG D 2 161 ? -54.242 -0.469  38.723  1    51.48  ? 157 ARG C O   1 
ATOM   7902 C  CB  . ARG D 2 161 ? -54.128 -3.969  38.447  1    59.38  ? 157 ARG C CB  1 
ATOM   7903 C  CG  . ARG D 2 161 ? -52.616 -3.81   38.416  1    67.16  ? 157 ARG C CG  1 
ATOM   7904 C  CD  . ARG D 2 161 ? -51.918 -4.749  39.381  1    77.72  ? 157 ARG C CD  1 
ATOM   7905 N  NE  . ARG D 2 161 ? -50.485 -4.861  39.089  1    87.41  ? 157 ARG C NE  1 
ATOM   7906 C  CZ  . ARG D 2 161 ? -49.517 -4.433  39.886  1    82.55  ? 157 ARG C CZ  1 
ATOM   7907 N  NH1 . ARG D 2 161 ? -48.296 -4.904  39.742  1    72.87  ? 157 ARG C NH1 1 
ATOM   7908 N  NH2 . ARG D 2 161 ? -49.768 -3.539  40.824  1    75.81  ? 157 ARG C NH2 1 
ATOM   7909 N  N   . THR D 2 162 ? -54.445 -1.825  40.523  1    57.03  ? 158 THR C N   1 
ATOM   7910 C  CA  . THR D 2 162 ? -54.048 -0.798  41.484  1    56.42  ? 158 THR C CA  1 
ATOM   7911 C  C   . THR D 2 162 ? -52.545 -0.551  41.352  1    54.38  ? 158 THR C C   1 
ATOM   7912 O  O   . THR D 2 162 ? -51.748 -1.484  41.478  1    54.57  ? 158 THR C O   1 
ATOM   7913 C  CB  . THR D 2 162 ? -54.423 -1.187  42.921  1    59.14  ? 158 THR C CB  1 
ATOM   7914 O  OG1 . THR D 2 162 ? -55.841 -1.179  42.995  1    66.33  ? 158 THR C OG1 1 
ATOM   7915 C  CG2 . THR D 2 162 ? -53.931 -0.206  43.977  1    56.16  ? 158 THR C CG2 1 
ATOM   7916 N  N   . TYR D 2 163 ? -52.181 0.717   41.131  1    50.4   ? 159 TYR C N   1 
ATOM   7917 C  CA  . TYR D 2 163 ? -50.791 1.152   41.089  1    49.48  ? 159 TYR C CA  1 
ATOM   7918 C  C   . TYR D 2 163 ? -50.531 2.097   42.258  1    49.28  ? 159 TYR C C   1 
ATOM   7919 O  O   . TYR D 2 163 ? -51.419 2.318   43.08   1    55.1   ? 159 TYR C O   1 
ATOM   7920 C  CB  . TYR D 2 163 ? -50.522 1.824   39.739  1    50.76  ? 159 TYR C CB  1 
ATOM   7921 C  CG  . TYR D 2 163 ? -50.88  0.952   38.549  1    51.22  ? 159 TYR C CG  1 
ATOM   7922 C  CD1 . TYR D 2 163 ? -50.511 -0.385  38.516  1    51.92  ? 159 TYR C CD1 1 
ATOM   7923 C  CD2 . TYR D 2 163 ? -51.612 1.456   37.485  1    51.42  ? 159 TYR C CD2 1 
ATOM   7924 C  CE1 . TYR D 2 163 ? -50.831 -1.198  37.446  1    53.51  ? 159 TYR C CE1 1 
ATOM   7925 C  CE2 . TYR D 2 163 ? -51.925 0.657   36.4    1    50.24  ? 159 TYR C CE2 1 
ATOM   7926 C  CZ  . TYR D 2 163 ? -51.535 -0.674  36.377  1    54.09  ? 159 TYR C CZ  1 
ATOM   7927 O  OH  . TYR D 2 163 ? -51.842 -1.511  35.327  1    59.22  ? 159 TYR C OH  1 
HETATM 7928 N  N   . TPO D 2 164 ? -49.298 2.62    42.343  1    49.02  ? 160 TPO C N   1 
HETATM 7929 C  CA  . TPO D 2 164 ? -48.864 3.568   43.364  1    47.45  ? 160 TPO C CA  1 
HETATM 7930 C  CB  . TPO D 2 164 ? -47.437 4.02    43.014  1    47.08  ? 160 TPO C CB  1 
HETATM 7931 C  CG2 . TPO D 2 164 ? -46.83  5.029   43.972  1    45.05  ? 160 TPO C CG2 1 
HETATM 7932 O  OG1 . TPO D 2 164 ? -46.567 2.824   42.97   1    46.35  ? 160 TPO C OG1 1 
HETATM 7933 P  P   . TPO D 2 164 ? -45.934 2.459   41.525  1    42.85  ? 160 TPO C P   1 
HETATM 7934 O  O1P . TPO D 2 164 ? -47.094 2.296   40.6    1    43.78  ? 160 TPO C O1P 1 
HETATM 7935 O  O2P . TPO D 2 164 ? -45.105 1.219   41.706  1    41.47  ? 160 TPO C O2P 1 
HETATM 7936 O  O3P . TPO D 2 164 ? -45.101 3.669   41.127  1    42.7   ? 160 TPO C O3P 1 
HETATM 7937 C  C   . TPO D 2 164 ? -49.838 4.755   43.437  1    49.44  ? 160 TPO C C   1 
HETATM 7938 O  O   . TPO D 2 164 ? -50.186 5.326   42.39   1    48.17  ? 160 TPO C O   1 
ATOM   7939 N  N   . HIS D 2 165 ? -50.287 5.122   44.657  1    51.81  ? 161 HIS C N   1 
ATOM   7940 C  CA  . HIS D 2 165 ? -51.19  6.265   44.831  1    62.98  ? 161 HIS C CA  1 
ATOM   7941 C  C   . HIS D 2 165 ? -50.436 7.606   44.885  1    66.25  ? 161 HIS C C   1 
ATOM   7942 O  O   . HIS D 2 165 ? -50.902 8.628   44.368  1    61.54  ? 161 HIS C O   1 
ATOM   7943 C  CB  . HIS D 2 165 ? -52.148 6.031   46.004  1    69.95  ? 161 HIS C CB  1 
ATOM   7944 C  CG  . HIS D 2 165 ? -52.958 7.215   46.438  1    90.28  ? 161 HIS C CG  1 
ATOM   7945 N  ND1 . HIS D 2 165 ? -52.419 8.33    47.057  1    95.19  ? 161 HIS C ND1 1 
ATOM   7946 C  CD2 . HIS D 2 165 ? -54.282 7.438   46.376  1    97.36  ? 161 HIS C CD2 1 
ATOM   7947 C  CE1 . HIS D 2 165 ? -53.385 9.186   47.365  1    94.13  ? 161 HIS C CE1 1 
ATOM   7948 N  NE2 . HIS D 2 165 ? -54.524 8.66    46.964  1    102.03 ? 161 HIS C NE2 1 
ATOM   7949 N  N   . GLU D 2 166 ? -49.258 7.598   45.517  1    71.58  ? 162 GLU C N   1 
ATOM   7950 C  CA  . GLU D 2 166 ? -48.442 8.795   45.664  1    80.29  ? 162 GLU C CA  1 
ATOM   7951 C  C   . GLU D 2 166 ? -47.794 9.1     44.307  1    82.3   ? 162 GLU C C   1 
ATOM   7952 O  O   . GLU D 2 166 ? -46.6   8.847   44.127  1    82.6   ? 162 GLU C O   1 
ATOM   7953 C  CB  . GLU D 2 166 ? -47.498 8.715   46.881  1    80.04  ? 162 GLU C CB  1 
ATOM   7954 C  CG  . GLU D 2 166 ? -46.992 7.316   47.264  1    85.4   ? 162 GLU C CG  1 
ATOM   7955 C  CD  . GLU D 2 166 ? -47.939 6.233   47.819  1    91.66  ? 162 GLU C CD  1 
ATOM   7956 O  OE1 . GLU D 2 166 ? -47.909 5.029   47.394  1    82.83  ? 162 GLU C OE1 1 
ATOM   7957 O  OE2 . GLU D 2 166 ? -48.74  6.603   48.716  1    83.58  ? 162 GLU C OE2 1 
ATOM   7958 N  N   . VAL D 2 167 ? -48.587 9.619   43.351  1    73.18  ? 163 VAL C N   1 
ATOM   7959 C  CA  . VAL D 2 167 ? -48.086 9.859   41.995  1    70.82  ? 163 VAL C CA  1 
ATOM   7960 C  C   . VAL D 2 167 ? -48.624 11.188  41.49   1    61.14  ? 163 VAL C C   1 
ATOM   7961 O  O   . VAL D 2 167 ? -49.772 11.53   41.82   1    59.64  ? 163 VAL C O   1 
ATOM   7962 C  CB  . VAL D 2 167 ? -48.385 8.797   40.91   1    67.27  ? 163 VAL C CB  1 
ATOM   7963 C  CG1 . VAL D 2 167 ? -47.522 7.555   41.063  1    61.53  ? 163 VAL C CG1 1 
ATOM   7964 C  CG2 . VAL D 2 167 ? -49.87  8.466   40.836  1    59.47  ? 163 VAL C CG2 1 
ATOM   7965 N  N   . VAL D 2 168 ? -47.793 11.827  40.641  1    49.36  ? 164 VAL C N   1 
ATOM   7966 C  CA  . VAL D 2 168 ? -48.031 13.111  39.983  1    54.73  ? 164 VAL C CA  1 
ATOM   7967 C  C   . VAL D 2 168 ? -47.973 14.286  40.98   1    52.13  ? 164 VAL C C   1 
ATOM   7968 O  O   . VAL D 2 168 ? -48.606 14.272  42.039  1    57.01  ? 164 VAL C O   1 
ATOM   7969 C  CB  . VAL D 2 168 ? -49.164 13.2    38.915  1    57.61  ? 164 VAL C CB  1 
ATOM   7970 C  CG1 . VAL D 2 168 ? -50.439 12.449  39.258  1    58.83  ? 164 VAL C CG1 1 
ATOM   7971 C  CG2 . VAL D 2 168 ? -49.506 14.617  38.502  1    53.62  ? 164 VAL C CG2 1 
ATOM   7972 N  N   . THR D 2 169 ? -47.175 15.31   40.655  1    45.21  ? 165 THR C N   1 
ATOM   7973 C  CA  . THR D 2 169 ? -47.073 16.509  41.474  1    47.74  ? 165 THR C CA  1 
ATOM   7974 C  C   . THR D 2 169 ? -48.465 17.096  41.728  1    44.9   ? 165 THR C C   1 
ATOM   7975 O  O   . THR D 2 169 ? -49.28  17.181  40.816  1    45.16  ? 165 THR C O   1 
ATOM   7976 C  CB  . THR D 2 169 ? -46.171 17.515  40.751  1    52.8   ? 165 THR C CB  1 
ATOM   7977 O  OG1 . THR D 2 169 ? -45.022 16.751  40.395  1    58     ? 165 THR C OG1 1 
ATOM   7978 C  CG2 . THR D 2 169 ? -45.842 18.736  41.599  1    49.87  ? 165 THR C CG2 1 
ATOM   7979 N  N   . LEU D 2 170 ? -48.683 17.612  42.937  1    43.04  ? 166 LEU C N   1 
ATOM   7980 C  CA  . LEU D 2 170 ? -50.014 17.939  43.428  1    47.3   ? 166 LEU C CA  1 
ATOM   7981 C  C   . LEU D 2 170 ? -50.829 18.813  42.454  1    48.22  ? 166 LEU C C   1 
ATOM   7982 O  O   . LEU D 2 170 ? -52.008 18.56   42.185  1    51.31  ? 166 LEU C O   1 
ATOM   7983 C  CB  . LEU D 2 170 ? -49.834 18.613  44.79   1    44.87  ? 166 LEU C CB  1 
ATOM   7984 C  CG  . LEU D 2 170 ? -51.122 18.98   45.533  1    47.71  ? 166 LEU C CG  1 
ATOM   7985 C  CD1 . LEU D 2 170 ? -51.928 17.733  45.904  1    42.99  ? 166 LEU C CD1 1 
ATOM   7986 C  CD2 . LEU D 2 170 ? -50.833 19.877  46.751  1    47.02  ? 166 LEU C CD2 1 
ATOM   7987 N  N   . TRP D 2 171 ? -50.216 19.877  41.947  1    44.4   ? 167 TRP C N   1 
ATOM   7988 C  CA  . TRP D 2 171 ? -50.942 20.828  41.124  1    45.05  ? 167 TRP C CA  1 
ATOM   7989 C  C   . TRP D 2 171 ? -51.546 20.172  39.875  1    43.56  ? 167 TRP C C   1 
ATOM   7990 O  O   . TRP D 2 171 ? -52.541 20.668  39.354  1    43.7   ? 167 TRP C O   1 
ATOM   7991 C  CB  . TRP D 2 171 ? -50.024 21.991  40.729  1    42.97  ? 167 TRP C CB  1 
ATOM   7992 C  CG  . TRP D 2 171 ? -49.549 22.836  41.872  1    47.59  ? 167 TRP C CG  1 
ATOM   7993 C  CD1 . TRP D 2 171 ? -49.872 22.733  43.195  1    49.16  ? 167 TRP C CD1 1 
ATOM   7994 C  CD2 . TRP D 2 171 ? -48.69  23.985  41.757  1    49.15  ? 167 TRP C CD2 1 
ATOM   7995 N  NE1 . TRP D 2 171 ? -49.26  23.72   43.914  1    46.06  ? 167 TRP C NE1 1 
ATOM   7996 C  CE2 . TRP D 2 171 ? -48.536 24.509  43.062  1    49     ? 167 TRP C CE2 1 
ATOM   7997 C  CE3 . TRP D 2 171 ? -48.031 24.601  40.689  1    48.66  ? 167 TRP C CE3 1 
ATOM   7998 C  CZ2 . TRP D 2 171 ? -47.744 25.626  43.319  1    50.65  ? 167 TRP C CZ2 1 
ATOM   7999 C  CZ3 . TRP D 2 171 ? -47.263 25.719  40.944  1    51.55  ? 167 TRP C CZ3 1 
ATOM   8000 C  CH2 . TRP D 2 171 ? -47.129 26.22   42.239  1    51.55  ? 167 TRP C CH2 1 
ATOM   8001 N  N   . TYR D 2 172 ? -50.914 19.101  39.369  1    41.06  ? 168 TYR C N   1 
ATOM   8002 C  CA  . TYR D 2 172 ? -51.25  18.493  38.083  1    40.31  ? 168 TYR C CA  1 
ATOM   8003 C  C   . TYR D 2 172 ? -52.007 17.192  38.332  1    38.9   ? 168 TYR C C   1 
ATOM   8004 O  O   . TYR D 2 172 ? -52.193 16.403  37.417  1    42.21  ? 168 TYR C O   1 
ATOM   8005 C  CB  . TYR D 2 172 ? -49.96  18.323  37.257  1    38.3   ? 168 TYR C CB  1 
ATOM   8006 C  CG  . TYR D 2 172 ? -49.245 19.652  37.053  1    39.16  ? 168 TYR C CG  1 
ATOM   8007 C  CD1 . TYR D 2 172 ? -49.628 20.53   36.046  1    38.54  ? 168 TYR C CD1 1 
ATOM   8008 C  CD2 . TYR D 2 172 ? -48.297 20.093  37.969  1    39.83  ? 168 TYR C CD2 1 
ATOM   8009 C  CE1 . TYR D 2 172 ? -49.074 21.796  35.938  1    40.79  ? 168 TYR C CE1 1 
ATOM   8010 C  CE2 . TYR D 2 172 ? -47.712 21.342  37.85   1    42.34  ? 168 TYR C CE2 1 
ATOM   8011 C  CZ  . TYR D 2 172 ? -48.092 22.204  36.831  1    44.61  ? 168 TYR C CZ  1 
ATOM   8012 O  OH  . TYR D 2 172 ? -47.482 23.443  36.738  1    44.1   ? 168 TYR C OH  1 
ATOM   8013 N  N   . ARG D 2 173 ? -52.431 16.97   39.584  1    39.32  ? 169 ARG C N   1 
ATOM   8014 C  CA  . ARG D 2 173 ? -52.996 15.692  39.992  1    41.24  ? 169 ARG C CA  1 
ATOM   8015 C  C   . ARG D 2 173 ? -54.506 15.678  39.741  1    42.59  ? 169 ARG C C   1 
ATOM   8016 O  O   . ARG D 2 173 ? -55.235 16.584  40.156  1    44.28  ? 169 ARG C O   1 
ATOM   8017 C  CB  . ARG D 2 173 ? -52.648 15.382  41.454  1    40.02  ? 169 ARG C CB  1 
ATOM   8018 C  CG  . ARG D 2 173 ? -53.075 13.987  41.892  1    39.82  ? 169 ARG C CG  1 
ATOM   8019 C  CD  . ARG D 2 173 ? -52.723 13.709  43.336  1    40.61  ? 169 ARG C CD  1 
ATOM   8020 N  NE  . ARG D 2 173 ? -51.278 13.834  43.57   1    43.63  ? 169 ARG C NE  1 
ATOM   8021 C  CZ  . ARG D 2 173 ? -50.666 14.024  44.749  1    43.47  ? 169 ARG C CZ  1 
ATOM   8022 N  NH1 . ARG D 2 173 ? -51.314 14.022  45.894  1    43.56  ? 169 ARG C NH1 1 
ATOM   8023 N  NH2 . ARG D 2 173 ? -49.377 14.232  44.788  1    43.76  ? 169 ARG C NH2 1 
ATOM   8024 N  N   . ALA D 2 174 ? -54.956 14.613  39.074  1    43.77  ? 170 ALA C N   1 
ATOM   8025 C  CA  . ALA D 2 174 ? -56.355 14.392  38.722  1    43.93  ? 170 ALA C CA  1 
ATOM   8026 C  C   . ALA D 2 174 ? -57.187 14.132  39.974  1    45.3   ? 170 ALA C C   1 
ATOM   8027 O  O   . ALA D 2 174 ? -56.715 13.519  40.931  1    49.84  ? 170 ALA C O   1 
ATOM   8028 C  CB  . ALA D 2 174 ? -56.463 13.223  37.772  1    40.19  ? 170 ALA C CB  1 
ATOM   8029 N  N   . PRO D 2 175 ? -58.459 14.564  40.001  1    44.19  ? 171 PRO C N   1 
ATOM   8030 C  CA  . PRO D 2 175 ? -59.297 14.37   41.184  1    46.28  ? 171 PRO C CA  1 
ATOM   8031 C  C   . PRO D 2 175 ? -59.576 12.917  41.588  1    49.44  ? 171 PRO C C   1 
ATOM   8032 O  O   . PRO D 2 175 ? -59.851 12.643  42.752  1    53.81  ? 171 PRO C O   1 
ATOM   8033 C  CB  . PRO D 2 175 ? -60.563 15.166  40.854  1    46.31  ? 171 PRO C CB  1 
ATOM   8034 C  CG  . PRO D 2 175 ? -60.604 15.182  39.341  1    46.64  ? 171 PRO C CG  1 
ATOM   8035 C  CD  . PRO D 2 175 ? -59.152 15.209  38.882  1    43.74  ? 171 PRO C CD  1 
ATOM   8036 N  N   . GLU D 2 176 ? -59.46  11.969  40.647  1    50.15  ? 172 GLU C N   1 
ATOM   8037 C  CA  . GLU D 2 176 ? -59.597 10.557  40.98   1    49.7   ? 172 GLU C CA  1 
ATOM   8038 C  C   . GLU D 2 176 ? -58.514 10.164  41.985  1    50.78  ? 172 GLU C C   1 
ATOM   8039 O  O   . GLU D 2 176 ? -58.811 9.464   42.954  1    51.45  ? 172 GLU C O   1 
ATOM   8040 C  CB  . GLU D 2 176 ? -59.744 9.639   39.762  1    47.37  ? 172 GLU C CB  1 
ATOM   8041 C  CG  . GLU D 2 176 ? -58.693 9.831   38.671  1    45.78  ? 172 GLU C CG  1 
ATOM   8042 C  CD  . GLU D 2 176 ? -58.984 10.753  37.487  1    50.17  ? 172 GLU C CD  1 
ATOM   8043 O  OE1 . GLU D 2 176 ? -58.588 10.369  36.339  1    45.38  ? 172 GLU C OE1 1 
ATOM   8044 O  OE2 . GLU D 2 176 ? -59.578 11.863  37.702  1    48.98  ? 172 GLU C OE2 1 
ATOM   8045 N  N   . ILE D 2 177 ? -57.277 10.656  41.797  1    49.7   ? 173 ILE C N   1 
ATOM   8046 C  CA  . ILE D 2 177 ? -56.195 10.269  42.702  1    54.07  ? 173 ILE C CA  1 
ATOM   8047 C  C   . ILE D 2 177 ? -56.383 10.924  44.067  1    58.01  ? 173 ILE C C   1 
ATOM   8048 O  O   . ILE D 2 177 ? -56.125 10.298  45.092  1    61.14  ? 173 ILE C O   1 
ATOM   8049 C  CB  . ILE D 2 177 ? -54.795 10.549  42.128  1    52.73  ? 173 ILE C CB  1 
ATOM   8050 C  CG1 . ILE D 2 177 ? -54.571 9.829   40.805  1    53     ? 173 ILE C CG1 1 
ATOM   8051 C  CG2 . ILE D 2 177 ? -53.713 10.166  43.131  1    50.55  ? 173 ILE C CG2 1 
ATOM   8052 C  CD1 . ILE D 2 177 ? -53.477 10.451  39.958  1    56.35  ? 173 ILE C CD1 1 
ATOM   8053 N  N   . LEU D 2 178 ? -56.83  12.185  44.057  1    59.84  ? 174 LEU C N   1 
ATOM   8054 C  CA  . LEU D 2 178 ? -57.034 12.998  45.248  1    56.26  ? 174 LEU C CA  1 
ATOM   8055 C  C   . LEU D 2 178 ? -58.126 12.378  46.112  1    56.79  ? 174 LEU C C   1 
ATOM   8056 O  O   . LEU D 2 178 ? -57.944 12.218  47.31   1    60.76  ? 174 LEU C O   1 
ATOM   8057 C  CB  . LEU D 2 178 ? -57.387 14.436  44.854  1    56.67  ? 174 LEU C CB  1 
ATOM   8058 C  CG  . LEU D 2 178 ? -56.295 15.271  44.172  1    53.56  ? 174 LEU C CG  1 
ATOM   8059 C  CD1 . LEU D 2 178 ? -56.909 16.486  43.466  1    53.27  ? 174 LEU C CD1 1 
ATOM   8060 C  CD2 . LEU D 2 178 ? -55.246 15.685  45.191  1    52.88  ? 174 LEU C CD2 1 
ATOM   8061 N  N   . LEU D 2 179 ? -59.255 12.017  45.491  1    55.13  ? 175 LEU C N   1 
ATOM   8062 C  CA  . LEU D 2 179 ? -60.338 11.336  46.18   1    58.09  ? 175 LEU C CA  1 
ATOM   8063 C  C   . LEU D 2 179 ? -59.989 9.876   46.525  1    62.13  ? 175 LEU C C   1 
ATOM   8064 O  O   . LEU D 2 179 ? -60.798 9.165   47.117  1    66.16  ? 175 LEU C O   1 
ATOM   8065 C  CB  . LEU D 2 179 ? -61.57  11.462  45.286  1    56.44  ? 175 LEU C CB  1 
ATOM   8066 C  CG  . LEU D 2 179 ? -62.105 12.88   45.083  1    55.37  ? 175 LEU C CG  1 
ATOM   8067 C  CD1 . LEU D 2 179 ? -63.26  12.922  44.123  1    57.43  ? 175 LEU C CD1 1 
ATOM   8068 C  CD2 . LEU D 2 179 ? -62.543 13.462  46.401  1    61.27  ? 175 LEU C CD2 1 
ATOM   8069 N  N   . GLY D 2 180 ? -58.784 9.414   46.155  1    63.54  ? 176 GLY C N   1 
ATOM   8070 C  CA  . GLY D 2 180 ? -58.207 8.166   46.645  1    58.52  ? 176 GLY C CA  1 
ATOM   8071 C  C   . GLY D 2 180 ? -58.896 6.925   46.078  1    57.23  ? 176 GLY C C   1 
ATOM   8072 O  O   . GLY D 2 180 ? -59.186 6.007   46.828  1    58.3   ? 176 GLY C O   1 
ATOM   8073 N  N   . CYS D 2 181 ? -59.134 6.908   44.76   1    55.14  ? 177 CYS C N   1 
ATOM   8074 C  CA  . CYS D 2 181 ? -59.866 5.845   44.092  1    58.17  ? 177 CYS C CA  1 
ATOM   8075 C  C   . CYS D 2 181 ? -58.965 4.626   43.909  1    56.7   ? 177 CYS C C   1 
ATOM   8076 O  O   . CYS D 2 181 ? -57.753 4.755   43.781  1    53.29  ? 177 CYS C O   1 
ATOM   8077 C  CB  . CYS D 2 181 ? -60.366 6.285   42.717  1    63.93  ? 177 CYS C CB  1 
ATOM   8078 S  SG  . CYS D 2 181 ? -61.763 7.451   42.728  1    76.01  ? 177 CYS C SG  1 
ATOM   8079 N  N   . LYS D 2 182 ? -59.584 3.446   43.869  1    57.85  ? 178 LYS C N   1 
ATOM   8080 C  CA  . LYS D 2 182 ? -58.878 2.179   43.73   1    60.59  ? 178 LYS C CA  1 
ATOM   8081 C  C   . LYS D 2 182 ? -58.074 2.134   42.427  1    55.47  ? 178 LYS C C   1 
ATOM   8082 O  O   . LYS D 2 182 ? -56.938 1.671   42.436  1    52.67  ? 178 LYS C O   1 
ATOM   8083 C  CB  . LYS D 2 182 ? -59.885 1.019   43.826  1    66.85  ? 178 LYS C CB  1 
ATOM   8084 C  CG  . LYS D 2 182 ? -59.296 -0.377  44.063  1    71.83  ? 178 LYS C CG  1 
ATOM   8085 C  CD  . LYS D 2 182 ? -60.315 -1.516  44.038  1    75.22  ? 178 LYS C CD  1 
ATOM   8086 C  CE  . LYS D 2 182 ? -59.744 -2.897  44.251  1    77.78  ? 178 LYS C CE  1 
ATOM   8087 N  NZ  . LYS D 2 182 ? -60.768 -3.955  44.293  1    78.24  ? 178 LYS C NZ  1 
ATOM   8088 N  N   . TYR D 2 183 ? -58.677 2.607   41.326  1    53.4   ? 179 TYR C N   1 
ATOM   8089 C  CA  . TYR D 2 183 ? -58.087 2.484   40.001  1    53.53  ? 179 TYR C CA  1 
ATOM   8090 C  C   . TYR D 2 183 ? -58.054 3.815   39.259  1    53.99  ? 179 TYR C C   1 
ATOM   8091 O  O   . TYR D 2 183 ? -59.03  4.566   39.268  1    58.36  ? 179 TYR C O   1 
ATOM   8092 C  CB  . TYR D 2 183 ? -58.9   1.587   39.071  1    54.52  ? 179 TYR C CB  1 
ATOM   8093 C  CG  . TYR D 2 183 ? -59.142 0.162   39.55   1    57.65  ? 179 TYR C CG  1 
ATOM   8094 C  CD1 . TYR D 2 183 ? -58.086 -0.729  39.717  1    55.82  ? 179 TYR C CD1 1 
ATOM   8095 C  CD2 . TYR D 2 183 ? -60.433 -0.312  39.762  1    58.42  ? 179 TYR C CD2 1 
ATOM   8096 C  CE1 . TYR D 2 183 ? -58.293 -2.035  40.129  1    58.53  ? 179 TYR C CE1 1 
ATOM   8097 C  CE2 . TYR D 2 183 ? -60.65  -1.617  40.164  1    60.47  ? 179 TYR C CE2 1 
ATOM   8098 C  CZ  . TYR D 2 183 ? -59.585 -2.482  40.341  1    61.69  ? 179 TYR C CZ  1 
ATOM   8099 O  OH  . TYR D 2 183 ? -59.833 -3.762  40.754  1    71.32  ? 179 TYR C OH  1 
ATOM   8100 N  N   . TYR D 2 184 ? -56.92  4.076   38.597  1    51.13  ? 180 TYR C N   1 
ATOM   8101 C  CA  . TYR D 2 184 ? -56.803 5.192   37.67   1    48.71  ? 180 TYR C CA  1 
ATOM   8102 C  C   . TYR D 2 184 ? -56.119 4.691   36.4    1    49.21  ? 180 TYR C C   1 
ATOM   8103 O  O   . TYR D 2 184 ? -55.481 3.633   36.385  1    49.6   ? 180 TYR C O   1 
ATOM   8104 C  CB  . TYR D 2 184 ? -56.047 6.375   38.284  1    47.37  ? 180 TYR C CB  1 
ATOM   8105 C  CG  . TYR D 2 184 ? -54.597 6.07    38.646  1    46.59  ? 180 TYR C CG  1 
ATOM   8106 C  CD1 . TYR D 2 184 ? -53.611 5.993   37.67   1    41.99  ? 180 TYR C CD1 1 
ATOM   8107 C  CD2 . TYR D 2 184 ? -54.221 5.824   39.965  1    48.85  ? 180 TYR C CD2 1 
ATOM   8108 C  CE1 . TYR D 2 184 ? -52.303 5.669   37.995  1    42.91  ? 180 TYR C CE1 1 
ATOM   8109 C  CE2 . TYR D 2 184 ? -52.906 5.534   40.305  1    48.16  ? 180 TYR C CE2 1 
ATOM   8110 C  CZ  . TYR D 2 184 ? -51.942 5.446   39.315  1    47.71  ? 180 TYR C CZ  1 
ATOM   8111 O  OH  . TYR D 2 184 ? -50.637 5.157   39.649  1    48.63  ? 180 TYR C OH  1 
ATOM   8112 N  N   . SER D 2 185 ? -56.227 5.494   35.341  1    47.92  ? 181 SER C N   1 
ATOM   8113 C  CA  . SER D 2 185 ? -55.868 5.054   34.004  1    49.42  ? 181 SER C CA  1 
ATOM   8114 C  C   . SER D 2 185 ? -55.252 6.214   33.231  1    45.57  ? 181 SER C C   1 
ATOM   8115 O  O   . SER D 2 185 ? -54.788 7.177   33.853  1    44.49  ? 181 SER C O   1 
ATOM   8116 C  CB  . SER D 2 185 ? -57.086 4.517   33.284  1    52.75  ? 181 SER C CB  1 
ATOM   8117 O  OG  . SER D 2 185 ? -56.736 3.818   32.097  1    56.37  ? 181 SER C OG  1 
ATOM   8118 N  N   . THR D 2 186 ? -55.273 6.086   31.89   1    44.23  ? 182 THR C N   1 
ATOM   8119 C  CA  . THR D 2 186 ? -54.735 7.056   30.943  1    45.86  ? 182 THR C CA  1 
ATOM   8120 C  C   . THR D 2 186 ? -55.284 8.456   31.211  1    48.35  ? 182 THR C C   1 
ATOM   8121 O  O   . THR D 2 186 ? -54.589 9.44    30.974  1    48.83  ? 182 THR C O   1 
ATOM   8122 C  CB  . THR D 2 186 ? -54.994 6.649   29.496  1    45.06  ? 182 THR C CB  1 
ATOM   8123 O  OG1 . THR D 2 186 ? -56.406 6.661   29.31   1    47.25  ? 182 THR C OG1 1 
ATOM   8124 C  CG2 . THR D 2 186 ? -54.376 5.309   29.166  1    42.79  ? 182 THR C CG2 1 
ATOM   8125 N  N   . ALA D 2 187 ? -56.499 8.534   31.764  1    48.75  ? 183 ALA C N   1 
ATOM   8126 C  CA  . ALA D 2 187 ? -57.181 9.8     31.977  1    46.12  ? 183 ALA C CA  1 
ATOM   8127 C  C   . ALA D 2 187 ? -56.392 10.743  32.882  1    45.02  ? 183 ALA C C   1 
ATOM   8128 O  O   . ALA D 2 187 ? -56.541 11.956  32.765  1    46.48  ? 183 ALA C O   1 
ATOM   8129 C  CB  . ALA D 2 187 ? -58.589 9.563   32.47   1    46.05  ? 183 ALA C CB  1 
ATOM   8130 N  N   . VAL D 2 188 ? -55.555 10.206  33.776  1    44.18  ? 184 VAL C N   1 
ATOM   8131 C  CA  . VAL D 2 188 ? -54.854 11.064  34.72   1    44.27  ? 184 VAL C CA  1 
ATOM   8132 C  C   . VAL D 2 188 ? -53.84  11.911  33.948  1    46.04  ? 184 VAL C C   1 
ATOM   8133 O  O   . VAL D 2 188 ? -53.614 13.076  34.276  1    52.2   ? 184 VAL C O   1 
ATOM   8134 C  CB  . VAL D 2 188 ? -54.221 10.34   35.927  1    41.88  ? 184 VAL C CB  1 
ATOM   8135 C  CG1 . VAL D 2 188 ? -55.189 9.35    36.547  1    40.57  ? 184 VAL C CG1 1 
ATOM   8136 C  CG2 . VAL D 2 188 ? -52.886 9.681   35.607  1    39     ? 184 VAL C CG2 1 
ATOM   8137 N  N   . ASP D 2 189 ? -53.274 11.322  32.893  1    41.56  ? 185 ASP C N   1 
ATOM   8138 C  CA  . ASP D 2 189 ? -52.315 12.02   32.061  1    42.48  ? 185 ASP C CA  1 
ATOM   8139 C  C   . ASP D 2 189 ? -52.987 13.159  31.302  1    43.11  ? 185 ASP C C   1 
ATOM   8140 O  O   . ASP D 2 189 ? -52.355 14.193  31.085  1    46.56  ? 185 ASP C O   1 
ATOM   8141 C  CB  . ASP D 2 189 ? -51.596 11.071  31.115  1    41.73  ? 185 ASP C CB  1 
ATOM   8142 C  CG  . ASP D 2 189 ? -50.447 10.301  31.75   1    42.2   ? 185 ASP C CG  1 
ATOM   8143 O  OD1 . ASP D 2 189 ? -49.909 10.763  32.793  1    39.41  ? 185 ASP C OD1 1 
ATOM   8144 O  OD2 . ASP D 2 189 ? -50.133 9.218   31.222  1    44.72  ? 185 ASP C OD2 1 
ATOM   8145 N  N   . ILE D 2 190 ? -54.236 12.947  30.864  1    39.26  ? 186 ILE C N   1 
ATOM   8146 C  CA  . ILE D 2 190 ? -54.965 13.972  30.134  1    41.8   ? 186 ILE C CA  1 
ATOM   8147 C  C   . ILE D 2 190 ? -55.259 15.145  31.061  1    43.97  ? 186 ILE C C   1 
ATOM   8148 O  O   . ILE D 2 190 ? -55.2   16.307  30.656  1    45.18  ? 186 ILE C O   1 
ATOM   8149 C  CB  . ILE D 2 190 ? -56.247 13.433  29.463  1    44.28  ? 186 ILE C CB  1 
ATOM   8150 C  CG1 . ILE D 2 190 ? -55.906 12.476  28.307  1    40.47  ? 186 ILE C CG1 1 
ATOM   8151 C  CG2 . ILE D 2 190 ? -57.12  14.591  28.961  1    40.81  ? 186 ILE C CG2 1 
ATOM   8152 C  CD1 . ILE D 2 190 ? -55.335 13.192  27.099  1    37.45  ? 186 ILE C CD1 1 
ATOM   8153 N  N   . TRP D 2 191 ? -55.556 14.834  32.324  1    43.61  ? 187 TRP C N   1 
ATOM   8154 C  CA  . TRP D 2 191 ? -55.801 15.904  33.267  1    42.66  ? 187 TRP C CA  1 
ATOM   8155 C  C   . TRP D 2 191 ? -54.599 16.85   33.306  1    41.52  ? 187 TRP C C   1 
ATOM   8156 O  O   . TRP D 2 191 ? -54.71  18.051  33.094  1    43.05  ? 187 TRP C O   1 
ATOM   8157 C  CB  . TRP D 2 191 ? -56.116 15.296  34.633  1    45.54  ? 187 TRP C CB  1 
ATOM   8158 C  CG  . TRP D 2 191 ? -56.465 16.333  35.662  1    46.52  ? 187 TRP C CG  1 
ATOM   8159 C  CD1 . TRP D 2 191 ? -55.592 16.949  36.509  1    44.57  ? 187 TRP C CD1 1 
ATOM   8160 C  CD2 . TRP D 2 191 ? -57.774 16.882  35.935  1    45.93  ? 187 TRP C CD2 1 
ATOM   8161 N  NE1 . TRP D 2 191 ? -56.27  17.823  37.317  1    47.85  ? 187 TRP C NE1 1 
ATOM   8162 C  CE2 . TRP D 2 191 ? -57.603 17.809  36.987  1    45.55  ? 187 TRP C CE2 1 
ATOM   8163 C  CE3 . TRP D 2 191 ? -59.055 16.672  35.404  1    44.76  ? 187 TRP C CE3 1 
ATOM   8164 C  CZ2 . TRP D 2 191 ? -58.671 18.519  37.52   1    43.91  ? 187 TRP C CZ2 1 
ATOM   8165 C  CZ3 . TRP D 2 191 ? -60.114 17.351  35.953  1    44.85  ? 187 TRP C CZ3 1 
ATOM   8166 C  CH2 . TRP D 2 191 ? -59.918 18.255  37.001  1    45.85  ? 187 TRP C CH2 1 
ATOM   8167 N  N   . SER D 2 192 ? -53.424 16.273  33.512  1    40.21  ? 188 SER C N   1 
ATOM   8168 C  CA  . SER D 2 192 ? -52.213 17.043  33.675  1    39.11  ? 188 SER C CA  1 
ATOM   8169 C  C   . SER D 2 192 ? -51.992 17.942  32.46   1    40.52  ? 188 SER C C   1 
ATOM   8170 O  O   . SER D 2 192 ? -51.647 19.111  32.614  1    41.2   ? 188 SER C O   1 
ATOM   8171 C  CB  . SER D 2 192 ? -51.037 16.12   33.923  1    41.14  ? 188 SER C CB  1 
ATOM   8172 O  OG  . SER D 2 192 ? -51.29  15.194  34.971  1    43.15  ? 188 SER C OG  1 
ATOM   8173 N  N   . LEU D 2 193 ? -52.22  17.399  31.253  1    40.36  ? 189 LEU C N   1 
ATOM   8174 C  CA  . LEU D 2 193 ? -52.056 18.157  30.021  1    40.78  ? 189 LEU C CA  1 
ATOM   8175 C  C   . LEU D 2 193 ? -53.048 19.312  29.997  1    43.67  ? 189 LEU C C   1 
ATOM   8176 O  O   . LEU D 2 193 ? -52.724 20.393  29.512  1    46.78  ? 189 LEU C O   1 
ATOM   8177 C  CB  . LEU D 2 193 ? -52.223 17.297  28.768  1    38.32  ? 189 LEU C CB  1 
ATOM   8178 C  CG  . LEU D 2 193 ? -50.987 16.565  28.244  1    41.86  ? 189 LEU C CG  1 
ATOM   8179 C  CD1 . LEU D 2 193 ? -51.245 16.224  26.792  1    44.23  ? 189 LEU C CD1 1 
ATOM   8180 C  CD2 . LEU D 2 193 ? -49.67  17.334  28.352  1    42.11  ? 189 LEU C CD2 1 
ATOM   8181 N  N   . GLY D 2 194 ? -54.272 19.051  30.469  1    42.53  ? 190 GLY C N   1 
ATOM   8182 C  CA  . GLY D 2 194 ? -55.278 20.087  30.575  1    42.21  ? 190 GLY C CA  1 
ATOM   8183 C  C   . GLY D 2 194 ? -54.812 21.253  31.437  1    42.72  ? 190 GLY C C   1 
ATOM   8184 O  O   . GLY D 2 194 ? -54.925 22.41   31.027  1    45.35  ? 190 GLY C O   1 
ATOM   8185 N  N   . CYS D 2 195 ? -54.259 20.919  32.608  1    42.62  ? 191 CYS C N   1 
ATOM   8186 C  CA  . CYS D 2 195 ? -53.666 21.899  33.509  1    45.53  ? 191 CYS C CA  1 
ATOM   8187 C  C   . CYS D 2 195 ? -52.52  22.65   32.808  1    46.8   ? 191 CYS C C   1 
ATOM   8188 O  O   . CYS D 2 195 ? -52.339 23.855  32.992  1    46.16  ? 191 CYS C O   1 
ATOM   8189 C  CB  . CYS D 2 195 ? -53.201 21.222  34.794  1    43.76  ? 191 CYS C CB  1 
ATOM   8190 S  SG  . CYS D 2 195 ? -54.55  20.439  35.718  1    46.86  ? 191 CYS C SG  1 
ATOM   8191 N  N   . ILE D 2 196 ? -51.773 21.936  31.96   1    43.07  ? 192 ILE C N   1 
ATOM   8192 C  CA  . ILE D 2 196 ? -50.664 22.534  31.24   1    44.48  ? 192 ILE C CA  1 
ATOM   8193 C  C   . ILE D 2 196 ? -51.16  23.443  30.103  1    45.82  ? 192 ILE C C   1 
ATOM   8194 O  O   . ILE D 2 196 ? -50.617 24.541  29.925  1    45.85  ? 192 ILE C O   1 
ATOM   8195 C  CB  . ILE D 2 196 ? -49.671 21.436  30.811  1    44.76  ? 192 ILE C CB  1 
ATOM   8196 C  CG1 . ILE D 2 196 ? -48.92  20.948  32.048  1    40.96  ? 192 ILE C CG1 1 
ATOM   8197 C  CG2 . ILE D 2 196 ? -48.707 21.914  29.714  1    39.17  ? 192 ILE C CG2 1 
ATOM   8198 C  CD1 . ILE D 2 196 ? -48.468 19.513  31.958  1    42.76  ? 192 ILE C CD1 1 
ATOM   8199 N  N   . PHE D 2 197 ? -52.193 23.007  29.353  1    40.66  ? 193 PHE C N   1 
ATOM   8200 C  CA  . PHE D 2 197 ? -52.811 23.87   28.36   1    38.53  ? 193 PHE C CA  1 
ATOM   8201 C  C   . PHE D 2 197 ? -53.179 25.198  29.016  1    40.86  ? 193 PHE C C   1 
ATOM   8202 O  O   . PHE D 2 197 ? -52.79  26.252  28.529  1    41.55  ? 193 PHE C O   1 
ATOM   8203 C  CB  . PHE D 2 197 ? -54.008 23.122  27.784  1    38.46  ? 193 PHE C CB  1 
ATOM   8204 C  CG  . PHE D 2 197 ? -54.77  23.794  26.651  1    41.55  ? 193 PHE C CG  1 
ATOM   8205 C  CD1 . PHE D 2 197 ? -54.223 24.825  25.896  1    41.79  ? 193 PHE C CD1 1 
ATOM   8206 C  CD2 . PHE D 2 197 ? -56.032 23.333  26.29   1    43.76  ? 193 PHE C CD2 1 
ATOM   8207 C  CE1 . PHE D 2 197 ? -54.941 25.379  24.841  1    44.63  ? 193 PHE C CE1 1 
ATOM   8208 C  CE2 . PHE D 2 197 ? -56.733 23.895  25.23   1    43.33  ? 193 PHE C CE2 1 
ATOM   8209 C  CZ  . PHE D 2 197 ? -56.191 24.918  24.509  1    44.15  ? 193 PHE C CZ  1 
ATOM   8210 N  N   . ALA D 2 198 ? -53.914 25.134  30.136  1    41.53  ? 194 ALA C N   1 
ATOM   8211 C  CA  . ALA D 2 198 ? -54.362 26.319  30.848  1    42.41  ? 194 ALA C CA  1 
ATOM   8212 C  C   . ALA D 2 198 ? -53.174 27.236  31.12   1    43.85  ? 194 ALA C C   1 
ATOM   8213 O  O   . ALA D 2 198 ? -53.25  28.467  30.943  1    44.67  ? 194 ALA C O   1 
ATOM   8214 C  CB  . ALA D 2 198 ? -55.067 25.932  32.132  1    39.56  ? 194 ALA C CB  1 
ATOM   8215 N  N   . GLU D 2 199 ? -52.096 26.591  31.567  1    41.88  ? 195 GLU C N   1 
ATOM   8216 C  CA  . GLU D 2 199 ? -50.961 27.288  32.146  1    45.66  ? 195 GLU C CA  1 
ATOM   8217 C  C   . GLU D 2 199 ? -50.157 27.965  31.033  1    44.09  ? 195 GLU C C   1 
ATOM   8218 O  O   . GLU D 2 199 ? -49.633 29.057  31.234  1    44.78  ? 195 GLU C O   1 
ATOM   8219 C  CB  . GLU D 2 199 ? -50.2   26.311  33.047  1    45.03  ? 195 GLU C CB  1 
ATOM   8220 C  CG  . GLU D 2 199 ? -49.124 26.971  33.898  1    45.05  ? 195 GLU C CG  1 
ATOM   8221 C  CD  . GLU D 2 199 ? -48.327 26.011  34.765  1    49.39  ? 195 GLU C CD  1 
ATOM   8222 O  OE1 . GLU D 2 199 ? -48.802 24.876  34.993  1    48.03  ? 195 GLU C OE1 1 
ATOM   8223 O  OE2 . GLU D 2 199 ? -47.208 26.394  35.204  1    52.62  ? 195 GLU C OE2 1 
ATOM   8224 N  N   . MET D 2 200 ? -50.104 27.334  29.855  1    42.44  ? 196 MET C N   1 
ATOM   8225 C  CA  . MET D 2 200 ? -49.475 27.933  28.683  1    43.92  ? 196 MET C CA  1 
ATOM   8226 C  C   . MET D 2 200 ? -50.213 29.217  28.295  1    50.37  ? 196 MET C C   1 
ATOM   8227 O  O   . MET D 2 200 ? -49.589 30.23   28.002  1    57.91  ? 196 MET C O   1 
ATOM   8228 C  CB  . MET D 2 200 ? -49.421 26.971  27.492  1    40.09  ? 196 MET C CB  1 
ATOM   8229 C  CG  . MET D 2 200 ? -48.3   25.964  27.574  1    40.78  ? 196 MET C CG  1 
ATOM   8230 S  SD  . MET D 2 200 ? -48.014 25.012  26.071  1    48.31  ? 196 MET C SD  1 
ATOM   8231 C  CE  . MET D 2 200 ? -49.402 23.871  26.017  1    43.51  ? 196 MET C CE  1 
ATOM   8232 N  N   . VAL D 2 201 ? -51.549 29.202  28.362  1    51.21  ? 197 VAL C N   1 
ATOM   8233 C  CA  . VAL D 2 201 ? -52.345 30.362  27.993  1    50.51  ? 197 VAL C CA  1 
ATOM   8234 C  C   . VAL D 2 201 ? -52.157 31.532  28.961  1    52.16  ? 197 VAL C C   1 
ATOM   8235 O  O   . VAL D 2 201 ? -52.09  32.666  28.498  1    58.15  ? 197 VAL C O   1 
ATOM   8236 C  CB  . VAL D 2 201 ? -53.83  29.996  27.875  1    49.79  ? 197 VAL C CB  1 
ATOM   8237 C  CG1 . VAL D 2 201 ? -54.695 31.249  27.749  1    51.71  ? 197 VAL C CG1 1 
ATOM   8238 C  CG2 . VAL D 2 201 ? -54.064 29.009  26.735  1    46.92  ? 197 VAL C CG2 1 
ATOM   8239 N  N   . THR D 2 202 ? -52.148 31.264  30.281  1    50.67  ? 198 THR C N   1 
ATOM   8240 C  CA  . THR D 2 202 ? -52.113 32.29   31.326  1    49.35  ? 198 THR C CA  1 
ATOM   8241 C  C   . THR D 2 202 ? -50.715 32.433  31.931  1    48.8   ? 198 THR C C   1 
ATOM   8242 O  O   . THR D 2 202 ? -50.446 33.419  32.613  1    46.34  ? 198 THR C O   1 
ATOM   8243 C  CB  . THR D 2 202 ? -53.103 31.999  32.459  1    49.02  ? 198 THR C CB  1 
ATOM   8244 O  OG1 . THR D 2 202 ? -52.619 30.839  33.126  1    52.51  ? 198 THR C OG1 1 
ATOM   8245 C  CG2 . THR D 2 202 ? -54.527 31.756  32      1    48     ? 198 THR C CG2 1 
ATOM   8246 N  N   . ARG D 2 203 ? -49.859 31.408  31.783  1    49.43  ? 199 ARG C N   1 
ATOM   8247 C  CA  . ARG D 2 203 ? -48.522 31.431  32.371  1    55.86  ? 199 ARG C CA  1 
ATOM   8248 C  C   . ARG D 2 203 ? -48.572 31.447  33.906  1    57.48  ? 199 ARG C C   1 
ATOM   8249 O  O   . ARG D 2 203 ? -47.643 31.9    34.559  1    57.94  ? 199 ARG C O   1 
ATOM   8250 C  CB  . ARG D 2 203 ? -47.707 32.607  31.811  1    60.3   ? 199 ARG C CB  1 
ATOM   8251 C  CG  . ARG D 2 203 ? -46.998 32.341  30.491  1    57.84  ? 199 ARG C CG  1 
ATOM   8252 C  CD  . ARG D 2 203 ? -46.353 33.62   30.002  1    65.58  ? 199 ARG C CD  1 
ATOM   8253 N  NE  . ARG D 2 203 ? -47.375 34.454  29.364  1    69.65  ? 199 ARG C NE  1 
ATOM   8254 C  CZ  . ARG D 2 203 ? -47.627 35.716  29.646  1    71.97  ? 199 ARG C CZ  1 
ATOM   8255 N  NH1 . ARG D 2 203 ? -46.833 36.406  30.446  1    75.09  ? 199 ARG C NH1 1 
ATOM   8256 N  NH2 . ARG D 2 203 ? -48.684 36.287  29.112  1    78.25  ? 199 ARG C NH2 1 
ATOM   8257 N  N   . ARG D 2 204 ? -49.681 30.966  34.471  1    56.52  ? 200 ARG C N   1 
ATOM   8258 C  CA  . ARG D 2 204 ? -49.849 30.753  35.892  1    53.36  ? 200 ARG C CA  1 
ATOM   8259 C  C   . ARG D 2 204 ? -50.485 29.383  36.006  1    53.8   ? 200 ARG C C   1 
ATOM   8260 O  O   . ARG D 2 204 ? -51.271 29.012  35.138  1    54.61  ? 200 ARG C O   1 
ATOM   8261 C  CB  . ARG D 2 204 ? -50.908 31.691  36.481  1    54.38  ? 200 ARG C CB  1 
ATOM   8262 C  CG  . ARG D 2 204 ? -50.58  33.169  36.405  1    58.71  ? 200 ARG C CG  1 
ATOM   8263 C  CD  . ARG D 2 204 ? -51.742 34.004  36.914  1    66.76  ? 200 ARG C CD  1 
ATOM   8264 N  NE  . ARG D 2 204 ? -51.424 35.435  36.801  1    73.65  ? 200 ARG C NE  1 
ATOM   8265 C  CZ  . ARG D 2 204 ? -51.751 36.214  35.765  1    73.39  ? 200 ARG C CZ  1 
ATOM   8266 N  NH1 . ARG D 2 204 ? -52.445 35.703  34.769  1    74.48  ? 200 ARG C NH1 1 
ATOM   8267 N  NH2 . ARG D 2 204 ? -51.378 37.484  35.71   1    70.46  ? 200 ARG C NH2 1 
ATOM   8268 N  N   . ALA D 2 205 ? -50.154 28.651  37.075  1    53.64  ? 201 ALA C N   1 
ATOM   8269 C  CA  . ALA D 2 205 ? -50.718 27.324  37.263  1    48.67  ? 201 ALA C CA  1 
ATOM   8270 C  C   . ALA D 2 205 ? -52.216 27.465  37.485  1    47.01  ? 201 ALA C C   1 
ATOM   8271 O  O   . ALA D 2 205 ? -52.666 28.462  38.037  1    46.03  ? 201 ALA C O   1 
ATOM   8272 C  CB  . ALA D 2 205 ? -50.049 26.616  38.414  1    47.81  ? 201 ALA C CB  1 
ATOM   8273 N  N   . LEU D 2 206 ? -52.969 26.47   37.019  1    44.98  ? 202 LEU C N   1 
ATOM   8274 C  CA  . LEU D 2 206 ? -54.411 26.525  37.116  1    45.12  ? 202 LEU C CA  1 
ATOM   8275 C  C   . LEU D 2 206 ? -54.838 26.197  38.544  1    47.29  ? 202 LEU C C   1 
ATOM   8276 O  O   . LEU D 2 206 ? -55.596 26.952  39.141  1    48.69  ? 202 LEU C O   1 
ATOM   8277 C  CB  . LEU D 2 206 ? -54.978 25.546  36.095  1    43.12  ? 202 LEU C CB  1 
ATOM   8278 C  CG  . LEU D 2 206 ? -56.505 25.473  36.004  1    45.07  ? 202 LEU C CG  1 
ATOM   8279 C  CD1 . LEU D 2 206 ? -57.148 26.815  35.622  1    44.62  ? 202 LEU C CD1 1 
ATOM   8280 C  CD2 . LEU D 2 206 ? -56.884 24.342  35.045  1    41.93  ? 202 LEU C CD2 1 
ATOM   8281 N  N   . PHE D 2 207 ? -54.317 25.102  39.112  1    46.63  ? 203 PHE C N   1 
ATOM   8282 C  CA  . PHE D 2 207 ? -54.725 24.746  40.464  1    49.17  ? 203 PHE C CA  1 
ATOM   8283 C  C   . PHE D 2 207 ? -53.518 24.642  41.396  1    48.65  ? 203 PHE C C   1 
ATOM   8284 O  O   . PHE D 2 207 ? -53.066 23.535  41.698  1    49.72  ? 203 PHE C O   1 
ATOM   8285 C  CB  . PHE D 2 207 ? -55.45  23.4    40.405  1    50     ? 203 PHE C CB  1 
ATOM   8286 C  CG  . PHE D 2 207 ? -56.645 23.363  39.471  1    48.22  ? 203 PHE C CG  1 
ATOM   8287 C  CD1 . PHE D 2 207 ? -57.659 24.31   39.558  1    47.05  ? 203 PHE C CD1 1 
ATOM   8288 C  CD2 . PHE D 2 207 ? -56.756 22.361  38.524  1    47.22  ? 203 PHE C CD2 1 
ATOM   8289 C  CE1 . PHE D 2 207 ? -58.759 24.255  38.719  1    47.24  ? 203 PHE C CE1 1 
ATOM   8290 C  CE2 . PHE D 2 207 ? -57.859 22.327  37.674  1    48.59  ? 203 PHE C CE2 1 
ATOM   8291 C  CZ  . PHE D 2 207 ? -58.863 23.261  37.778  1    47.08  ? 203 PHE C CZ  1 
ATOM   8292 N  N   . PRO D 2 208 ? -52.985 25.773  41.915  1    49.44  ? 204 PRO C N   1 
ATOM   8293 C  CA  . PRO D 2 208 ? -51.828 25.73   42.816  1    51.84  ? 204 PRO C CA  1 
ATOM   8294 C  C   . PRO D 2 208 ? -52.191 25.44   44.271  1    56.55  ? 204 PRO C C   1 
ATOM   8295 O  O   . PRO D 2 208 ? -52.178 26.353  45.101  1    63.86  ? 204 PRO C O   1 
ATOM   8296 C  CB  . PRO D 2 208 ? -51.273 27.158  42.668  1    49.78  ? 204 PRO C CB  1 
ATOM   8297 C  CG  . PRO D 2 208 ? -52.507 28.003  42.482  1    47.61  ? 204 PRO C CG  1 
ATOM   8298 C  CD  . PRO D 2 208 ? -53.464 27.146  41.669  1    48.02  ? 204 PRO C CD  1 
ATOM   8299 N  N   . GLY D 2 209 ? -52.48  24.17   44.58   1    52.1   ? 205 GLY C N   1 
ATOM   8300 C  CA  . GLY D 2 209 ? -52.843 23.778  45.93   1    53.51  ? 205 GLY C CA  1 
ATOM   8301 C  C   . GLY D 2 209 ? -51.666 23.775  46.91   1    56.35  ? 205 GLY C C   1 
ATOM   8302 O  O   . GLY D 2 209 ? -50.539 23.456  46.549  1    56.63  ? 205 GLY C O   1 
ATOM   8303 N  N   . ASP D 2 210 ? -51.977 24.067  48.181  1    62.37  ? 206 ASP C N   1 
ATOM   8304 C  CA  . ASP D 2 210 ? -51.051 24.021  49.306  1    66.69  ? 206 ASP C CA  1 
ATOM   8305 C  C   . ASP D 2 210 ? -51.09  22.648  49.98   1    67.34  ? 206 ASP C C   1 
ATOM   8306 O  O   . ASP D 2 210 ? -50.183 22.313  50.732  1    66.44  ? 206 ASP C O   1 
ATOM   8307 C  CB  . ASP D 2 210 ? -51.393 25.102  50.319  1    74.96  ? 206 ASP C CB  1 
ATOM   8308 C  CG  . ASP D 2 210 ? -51.569 26.502  49.744  1    83.78  ? 206 ASP C CG  1 
ATOM   8309 O  OD1 . ASP D 2 210 ? -50.695 26.894  48.937  1    84.42  ? 206 ASP C OD1 1 
ATOM   8310 O  OD2 . ASP D 2 210 ? -52.57  27.185  50.11   1    85.8   ? 206 ASP C OD2 1 
ATOM   8311 N  N   . SER D 2 211 ? -52.123 21.845  49.676  1    67.43  ? 207 SER C N   1 
ATOM   8312 C  CA  . SER D 2 211 ? -52.416 20.596  50.369  1    65.1   ? 207 SER C CA  1 
ATOM   8313 C  C   . SER D 2 211 ? -53.429 19.799  49.547  1    65.53  ? 207 SER C C   1 
ATOM   8314 O  O   . SER D 2 211 ? -53.932 20.305  48.547  1    69.66  ? 207 SER C O   1 
ATOM   8315 C  CB  . SER D 2 211 ? -52.928 20.864  51.766  1    61.93  ? 207 SER C CB  1 
ATOM   8316 O  OG  . SER D 2 211 ? -54.305 21.226  51.759  1    61.86  ? 207 SER C OG  1 
ATOM   8317 N  N   . GLU D 2 212 ? -53.743 18.568  49.968  1    63.13  ? 208 GLU C N   1 
ATOM   8318 C  CA  . GLU D 2 212 ? -54.682 17.744  49.221  1    63.52  ? 208 GLU C CA  1 
ATOM   8319 C  C   . GLU D 2 212 ? -56.102 18.309  49.28   1    61.96  ? 208 GLU C C   1 
ATOM   8320 O  O   . GLU D 2 212 ? -56.796 18.385  48.267  1    58.39  ? 208 GLU C O   1 
ATOM   8321 C  CB  . GLU D 2 212 ? -54.607 16.299  49.702  1    65.26  ? 208 GLU C CB  1 
ATOM   8322 C  CG  . GLU D 2 212 ? -53.382 15.601  49.131  1    70.58  ? 208 GLU C CG  1 
ATOM   8323 C  CD  . GLU D 2 212 ? -53.189 14.168  49.574  1    76.31  ? 208 GLU C CD  1 
ATOM   8324 O  OE1 . GLU D 2 212 ? -54.154 13.374  49.535  1    75.51  ? 208 GLU C OE1 1 
ATOM   8325 O  OE2 . GLU D 2 212 ? -52.035 13.86   49.935  1    74.9   ? 208 GLU C OE2 1 
ATOM   8326 N  N   . ILE D 2 213 ? -56.542 18.679  50.483  1    65.95  ? 209 ILE C N   1 
ATOM   8327 C  CA  . ILE D 2 213 ? -57.868 19.243  50.659  1    67.47  ? 209 ILE C CA  1 
ATOM   8328 C  C   . ILE D 2 213 ? -57.942 20.56   49.879  1    66.56  ? 209 ILE C C   1 
ATOM   8329 O  O   . ILE D 2 213 ? -58.953 20.837  49.228  1    66.35  ? 209 ILE C O   1 
ATOM   8330 C  CB  . ILE D 2 213 ? -58.218 19.389  52.156  1    67.47  ? 209 ILE C CB  1 
ATOM   8331 C  CG1 . ILE D 2 213 ? -59.675 19.79   52.363  1    75.73  ? 209 ILE C CG1 1 
ATOM   8332 C  CG2 . ILE D 2 213 ? -57.273 20.348  52.876  1    64.88  ? 209 ILE C CG2 1 
ATOM   8333 C  CD1 . ILE D 2 213 ? -60.655 18.626  52.358  1    78.36  ? 209 ILE C CD1 1 
ATOM   8334 N  N   . ASP D 2 214 ? -56.841 21.329  49.902  1    59.65  ? 210 ASP C N   1 
ATOM   8335 C  CA  . ASP D 2 214 ? -56.793 22.634  49.271  1    57.19  ? 210 ASP C CA  1 
ATOM   8336 C  C   . ASP D 2 214 ? -56.871 22.53   47.745  1    56.45  ? 210 ASP C C   1 
ATOM   8337 O  O   . ASP D 2 214 ? -57.577 23.313  47.105  1    52.84  ? 210 ASP C O   1 
ATOM   8338 C  CB  . ASP D 2 214 ? -55.547 23.387  49.67   1    57.65  ? 210 ASP C CB  1 
ATOM   8339 C  CG  . ASP D 2 214 ? -55.546 24.797  49.119  1    57.47  ? 210 ASP C CG  1 
ATOM   8340 O  OD1 . ASP D 2 214 ? -56.509 25.526  49.408  1    59.45  ? 210 ASP C OD1 1 
ATOM   8341 O  OD2 . ASP D 2 214 ? -54.605 25.139  48.387  1    56.34  ? 210 ASP C OD2 1 
ATOM   8342 N  N   . GLN D 2 215 ? -56.139 21.554  47.185  1    53.49  ? 211 GLN C N   1 
ATOM   8343 C  CA  . GLN D 2 215 ? -56.169 21.184  45.779  1    49.55  ? 211 GLN C CA  1 
ATOM   8344 C  C   . GLN D 2 215 ? -57.582 20.863  45.286  1    49.27  ? 211 GLN C C   1 
ATOM   8345 O  O   . GLN D 2 215 ? -57.966 21.298  44.202  1    51.54  ? 211 GLN C O   1 
ATOM   8346 C  CB  . GLN D 2 215 ? -55.287 19.964  45.535  1    51.94  ? 211 GLN C CB  1 
ATOM   8347 C  CG  . GLN D 2 215 ? -55.061 19.675  44.052  1    53.63  ? 211 GLN C CG  1 
ATOM   8348 C  CD  . GLN D 2 215 ? -54.22  20.741  43.39   1    54.25  ? 211 GLN C CD  1 
ATOM   8349 O  OE1 . GLN D 2 215 ? -53.496 21.478  44.068  1    54.96  ? 211 GLN C OE1 1 
ATOM   8350 N  NE2 . GLN D 2 215 ? -54.309 20.841  42.072  1    52.64  ? 211 GLN C NE2 1 
ATOM   8351 N  N   . LEU D 2 216 ? -58.342 20.07   46.05   1    50     ? 212 LEU C N   1 
ATOM   8352 C  CA  . LEU D 2 216 ? -59.707 19.731  45.678  1    48.84  ? 212 LEU C CA  1 
ATOM   8353 C  C   . LEU D 2 216 ? -60.579 20.987  45.642  1    50.52  ? 212 LEU C C   1 
ATOM   8354 O  O   . LEU D 2 216 ? -61.344 21.212  44.695  1    48.47  ? 212 LEU C O   1 
ATOM   8355 C  CB  . LEU D 2 216 ? -60.243 18.731  46.691  1    49.19  ? 212 LEU C CB  1 
ATOM   8356 C  CG  . LEU D 2 216 ? -60.013 17.271  46.324  1    52.17  ? 212 LEU C CG  1 
ATOM   8357 C  CD1 . LEU D 2 216 ? -60.529 16.383  47.43   1    53.57  ? 212 LEU C CD1 1 
ATOM   8358 C  CD2 . LEU D 2 216 ? -60.672 16.935  44.978  1    50.07  ? 212 LEU C CD2 1 
ATOM   8359 N  N   . PHE D 2 217 ? -60.456 21.798  46.697  1    50.3   ? 213 PHE C N   1 
ATOM   8360 C  CA  . PHE D 2 217 ? -61.246 23.009  46.821  1    51.98  ? 213 PHE C CA  1 
ATOM   8361 C  C   . PHE D 2 217 ? -60.954 23.921  45.634  1    52.38  ? 213 PHE C C   1 
ATOM   8362 O  O   . PHE D 2 217 ? -61.858 24.598  45.153  1    56.68  ? 213 PHE C O   1 
ATOM   8363 C  CB  . PHE D 2 217 ? -61.044 23.734  48.158  1    53.79  ? 213 PHE C CB  1 
ATOM   8364 C  CG  . PHE D 2 217 ? -61.57  23.066  49.424  1    54.33  ? 213 PHE C CG  1 
ATOM   8365 C  CD1 . PHE D 2 217 ? -62.361 21.918  49.375  1    55.11  ? 213 PHE C CD1 1 
ATOM   8366 C  CD2 . PHE D 2 217 ? -61.271 23.6    50.666  1    55.69  ? 213 PHE C CD2 1 
ATOM   8367 C  CE1 . PHE D 2 217 ? -62.819 21.316  50.535  1    56.19  ? 213 PHE C CE1 1 
ATOM   8368 C  CE2 . PHE D 2 217 ? -61.745 23.004  51.823  1    58.51  ? 213 PHE C CE2 1 
ATOM   8369 C  CZ  . PHE D 2 217 ? -62.523 21.871  51.761  1    57.86  ? 213 PHE C CZ  1 
ATOM   8370 N  N   . ARG D 2 218 ? -59.703 23.933  45.154  1    51.36  ? 214 ARG C N   1 
ATOM   8371 C  CA  . ARG D 2 218 ? -59.342 24.867  44.1    1    51.52  ? 214 ARG C CA  1 
ATOM   8372 C  C   . ARG D 2 218 ? -59.933 24.431  42.766  1    52.26  ? 214 ARG C C   1 
ATOM   8373 O  O   . ARG D 2 218 ? -60.324 25.265  41.949  1    57.26  ? 214 ARG C O   1 
ATOM   8374 C  CB  . ARG D 2 218 ? -57.83  25.026  43.979  1    50.63  ? 214 ARG C CB  1 
ATOM   8375 C  CG  . ARG D 2 218 ? -57.328 26.042  44.991  1    52.5   ? 214 ARG C CG  1 
ATOM   8376 C  CD  . ARG D 2 218 ? -55.817 26.045  44.868  1    53.37  ? 214 ARG C CD  1 
ATOM   8377 N  NE  . ARG D 2 218 ? -55.297 26.759  46.032  1    55.32  ? 214 ARG C NE  1 
ATOM   8378 C  CZ  . ARG D 2 218 ? -54.889 28.006  45.988  1    57.13  ? 214 ARG C CZ  1 
ATOM   8379 N  NH1 . ARG D 2 218 ? -55.006 28.7    44.861  1    55.29  ? 214 ARG C NH1 1 
ATOM   8380 N  NH2 . ARG D 2 218 ? -54.378 28.53   47.094  1    59.99  ? 214 ARG C NH2 1 
ATOM   8381 N  N   . ILE D 2 219 ? -59.938 23.115  42.554  1    49.91  ? 215 ILE C N   1 
ATOM   8382 C  CA  . ILE D 2 219 ? -60.589 22.501  41.414  1    48.95  ? 215 ILE C CA  1 
ATOM   8383 C  C   . ILE D 2 219 ? -62.105 22.787  41.443  1    52.09  ? 215 ILE C C   1 
ATOM   8384 O  O   . ILE D 2 219 ? -62.684 23.242  40.452  1    51.33  ? 215 ILE C O   1 
ATOM   8385 C  CB  . ILE D 2 219 ? -60.237 21.001  41.409  1    45.51  ? 215 ILE C CB  1 
ATOM   8386 C  CG1 . ILE D 2 219 ? -58.736 20.805  41.131  1    40.99  ? 215 ILE C CG1 1 
ATOM   8387 C  CG2 . ILE D 2 219 ? -61.145 20.222  40.449  1    43.53  ? 215 ILE C CG2 1 
ATOM   8388 C  CD1 . ILE D 2 219 ? -58.218 19.386  41.312  1    38.74  ? 215 ILE C CD1 1 
ATOM   8389 N  N   . PHE D 2 220 ? -62.748 22.527  42.589  1    52.11  ? 216 PHE C N   1 
ATOM   8390 C  CA  . PHE D 2 220 ? -64.181 22.729  42.737  1    54.02  ? 216 PHE C CA  1 
ATOM   8391 C  C   . PHE D 2 220 ? -64.578 24.191  42.544  1    56.54  ? 216 PHE C C   1 
ATOM   8392 O  O   . PHE D 2 220 ? -65.648 24.468  42.008  1    57.88  ? 216 PHE C O   1 
ATOM   8393 C  CB  . PHE D 2 220 ? -64.651 22.313  44.13   1    53.91  ? 216 PHE C CB  1 
ATOM   8394 C  CG  . PHE D 2 220 ? -64.441 20.846  44.458  1    52.26  ? 216 PHE C CG  1 
ATOM   8395 C  CD1 . PHE D 2 220 ? -64.028 19.938  43.485  1    49.11  ? 216 PHE C CD1 1 
ATOM   8396 C  CD2 . PHE D 2 220 ? -64.689 20.377  45.741  1    55.11  ? 216 PHE C CD2 1 
ATOM   8397 C  CE1 . PHE D 2 220 ? -63.859 18.6    43.798  1    47.48  ? 216 PHE C CE1 1 
ATOM   8398 C  CE2 . PHE D 2 220 ? -64.513 19.026  46.039  1    53.56  ? 216 PHE C CE2 1 
ATOM   8399 C  CZ  . PHE D 2 220 ? -64.093 18.148  45.073  1    48.52  ? 216 PHE C CZ  1 
ATOM   8400 N  N   . ARG D 2 221 ? -63.745 25.122  43.03   1    58.67  ? 217 ARG C N   1 
ATOM   8401 C  CA  . ARG D 2 221 ? -64.018 26.552  42.929  1    59.01  ? 217 ARG C CA  1 
ATOM   8402 C  C   . ARG D 2 221 ? -64.184 26.954  41.455  1    57.7   ? 217 ARG C C   1 
ATOM   8403 O  O   . ARG D 2 221 ? -65.001 27.813  41.113  1    60.34  ? 217 ARG C O   1 
ATOM   8404 C  CB  . ARG D 2 221 ? -62.952 27.344  43.706  1    57.03  ? 217 ARG C CB  1 
ATOM   8405 C  CG  . ARG D 2 221 ? -63.321 27.689  45.143  1    59.73  ? 217 ARG C CG  1 
ATOM   8406 C  CD  . ARG D 2 221 ? -62.219 28.241  46.037  1    59.19  ? 217 ARG C CD  1 
ATOM   8407 N  NE  . ARG D 2 221 ? -62.621 28.089  47.444  1    62.76  ? 217 ARG C NE  1 
ATOM   8408 C  CZ  . ARG D 2 221 ? -61.823 27.846  48.502  1    66.48  ? 217 ARG C CZ  1 
ATOM   8409 N  NH1 . ARG D 2 221 ? -60.523 27.606  48.367  1    65.68  ? 217 ARG C NH1 1 
ATOM   8410 N  NH2 . ARG D 2 221 ? -62.336 27.867  49.717  1    67.29  ? 217 ARG C NH2 1 
ATOM   8411 N  N   . THR D 2 222 ? -63.428 26.281  40.577  1    54.89  ? 218 THR C N   1 
ATOM   8412 C  CA  . THR D 2 222 ? -63.311 26.641  39.173  1    56.17  ? 218 THR C CA  1 
ATOM   8413 C  C   . THR D 2 222 ? -64.262 25.82   38.299  1    58.79  ? 218 THR C C   1 
ATOM   8414 O  O   . THR D 2 222 ? -64.899 26.381  37.407  1    59.92  ? 218 THR C O   1 
ATOM   8415 C  CB  . THR D 2 222 ? -61.869 26.411  38.727  1    53.67  ? 218 THR C CB  1 
ATOM   8416 O  OG1 . THR D 2 222 ? -61.108 27.392  39.416  1    51.22  ? 218 THR C OG1 1 
ATOM   8417 C  CG2 . THR D 2 222 ? -61.692 26.537  37.225  1    53.81  ? 218 THR C CG2 1 
ATOM   8418 N  N   . LEU D 2 223 ? -64.307 24.497  38.514  1    57.05  ? 219 LEU C N   1 
ATOM   8419 C  CA  . LEU D 2 223 ? -65.019 23.6    37.609  1    60.23  ? 219 LEU C CA  1 
ATOM   8420 C  C   . LEU D 2 223 ? -66.418 23.282  38.126  1    66.41  ? 219 LEU C C   1 
ATOM   8421 O  O   . LEU D 2 223 ? -67.185 22.625  37.422  1    70.58  ? 219 LEU C O   1 
ATOM   8422 C  CB  . LEU D 2 223 ? -64.251 22.297  37.4    1    56.94  ? 219 LEU C CB  1 
ATOM   8423 C  CG  . LEU D 2 223 ? -62.87  22.417  36.742  1    56.32  ? 219 LEU C CG  1 
ATOM   8424 C  CD1 . LEU D 2 223 ? -62.175 21.067  36.736  1    50.75  ? 219 LEU C CD1 1 
ATOM   8425 C  CD2 . LEU D 2 223 ? -62.904 23.016  35.33   1    53.41  ? 219 LEU C CD2 1 
ATOM   8426 N  N   . GLY D 2 224 ? -66.722 23.725  39.356  1    65.39  ? 220 GLY C N   1 
ATOM   8427 C  CA  . GLY D 2 224 ? -67.988 23.428  40.012  1    64.82  ? 220 GLY C CA  1 
ATOM   8428 C  C   . GLY D 2 224 ? -67.85  22.17   40.859  1    63.2   ? 220 GLY C C   1 
ATOM   8429 O  O   . GLY D 2 224 ? -67.15  21.251  40.461  1    63.46  ? 220 GLY C O   1 
ATOM   8430 N  N   . THR D 2 225 ? -68.468 22.147  42.044  1    65.64  ? 221 THR C N   1 
ATOM   8431 C  CA  . THR D 2 225 ? -68.339 20.979  42.907  1    65.95  ? 221 THR C CA  1 
ATOM   8432 C  C   . THR D 2 225 ? -69.051 19.817  42.238  1    68.41  ? 221 THR C C   1 
ATOM   8433 O  O   . THR D 2 225 ? -70.252 19.889  42.001  1    72.14  ? 221 THR C O   1 
ATOM   8434 C  CB  . THR D 2 225 ? -68.964 21.16   44.29   1    64.97  ? 221 THR C CB  1 
ATOM   8435 O  OG1 . THR D 2 225 ? -68.476 22.356  44.884  1    62.71  ? 221 THR C OG1 1 
ATOM   8436 C  CG2 . THR D 2 225 ? -68.736 19.925  45.146  1    59.22  ? 221 THR C CG2 1 
ATOM   8437 N  N   . PRO D 2 226 ? -68.376 18.673  42.012  1    72.2   ? 222 PRO C N   1 
ATOM   8438 C  CA  . PRO D 2 226 ? -69.03  17.552  41.332  1    72.17  ? 222 PRO C CA  1 
ATOM   8439 C  C   . PRO D 2 226 ? -70.151 16.937  42.169  1    76.29  ? 222 PRO C C   1 
ATOM   8440 O  O   . PRO D 2 226 ? -70.115 16.982  43.4    1    75.59  ? 222 PRO C O   1 
ATOM   8441 C  CB  . PRO D 2 226 ? -67.874 16.578  41.079  1    70.47  ? 222 PRO C CB  1 
ATOM   8442 C  CG  . PRO D 2 226 ? -66.844 16.912  42.15   1    67.71  ? 222 PRO C CG  1 
ATOM   8443 C  CD  . PRO D 2 226 ? -66.985 18.4    42.419  1    67.86  ? 222 PRO C CD  1 
ATOM   8444 N  N   . ASP D 2 227 ? -71.157 16.397  41.465  1    81.05  ? 223 ASP C N   1 
ATOM   8445 C  CA  . ASP D 2 227 ? -72.231 15.593  42.039  1    81.2   ? 223 ASP C CA  1 
ATOM   8446 C  C   . ASP D 2 227 ? -72.466 14.401  41.108  1    81.15  ? 223 ASP C C   1 
ATOM   8447 O  O   . ASP D 2 227 ? -71.732 14.236  40.135  1    77.73  ? 223 ASP C O   1 
ATOM   8448 C  CB  . ASP D 2 227 ? -73.465 16.434  42.35   1    82.36  ? 223 ASP C CB  1 
ATOM   8449 C  CG  . ASP D 2 227 ? -74.143 17.108  41.16   1    85.77  ? 223 ASP C CG  1 
ATOM   8450 O  OD1 . ASP D 2 227 ? -73.886 16.696  40.004  1    87.61  ? 223 ASP C OD1 1 
ATOM   8451 O  OD2 . ASP D 2 227 ? -74.905 18.073  41.39   1    86.46  ? 223 ASP C OD2 1 
ATOM   8452 N  N   . GLU D 2 228 ? -73.511 13.606  41.387  1    85.26  ? 224 GLU C N   1 
ATOM   8453 C  CA  . GLU D 2 228 ? -73.723 12.312  40.746  1    84.24  ? 224 GLU C CA  1 
ATOM   8454 C  C   . GLU D 2 228 ? -74.064 12.467  39.26   1    84.18  ? 224 GLU C C   1 
ATOM   8455 O  O   . GLU D 2 228 ? -73.573 11.709  38.43   1    87.57  ? 224 GLU C O   1 
ATOM   8456 C  CB  . GLU D 2 228 ? -74.729 11.486  41.548  1    84.23  ? 224 GLU C CB  1 
ATOM   8457 C  CG  . GLU D 2 228 ? -74.152 10.924  42.845  1    86.74  ? 224 GLU C CG  1 
ATOM   8458 C  CD  . GLU D 2 228 ? -73.224 9.719   42.753  1    87.03  ? 224 GLU C CD  1 
ATOM   8459 O  OE1 . GLU D 2 228 ? -73.313 8.97    41.765  1    88.24  ? 224 GLU C OE1 1 
ATOM   8460 O  OE2 . GLU D 2 228 ? -72.394 9.52    43.664  1    82.98  ? 224 GLU C OE2 1 
ATOM   8461 N  N   . VAL D 2 229 ? -74.883 13.472  38.934  1    83.12  ? 225 VAL C N   1 
ATOM   8462 C  CA  . VAL D 2 229 ? -75.235 13.818  37.563  1    81.49  ? 225 VAL C CA  1 
ATOM   8463 C  C   . VAL D 2 229 ? -73.994 14.133  36.717  1    77.78  ? 225 VAL C C   1 
ATOM   8464 O  O   . VAL D 2 229 ? -73.887 13.649  35.597  1    74.29  ? 225 VAL C O   1 
ATOM   8465 C  CB  . VAL D 2 229 ? -76.286 14.949  37.54   1    77.8   ? 225 VAL C CB  1 
ATOM   8466 C  CG1 . VAL D 2 229 ? -76.223 15.784  36.26   1    72.73  ? 225 VAL C CG1 1 
ATOM   8467 C  CG2 . VAL D 2 229 ? -77.683 14.396  37.801  1    74.8   ? 225 VAL C CG2 1 
ATOM   8468 N  N   . VAL D 2 230 ? -73.049 14.919  37.244  1    78.9   ? 226 VAL C N   1 
ATOM   8469 C  CA  . VAL D 2 230 ? -71.838 15.262  36.5    1    85.91  ? 226 VAL C CA  1 
ATOM   8470 C  C   . VAL D 2 230 ? -70.866 14.078  36.466  1    84.16  ? 226 VAL C C   1 
ATOM   8471 O  O   . VAL D 2 230 ? -70.174 13.845  35.471  1    81.43  ? 226 VAL C O   1 
ATOM   8472 C  CB  . VAL D 2 230 ? -71.1   16.52   37.004  1    85.75  ? 226 VAL C CB  1 
ATOM   8473 C  CG1 . VAL D 2 230 ? -69.981 16.895  36.041  1    75.9   ? 226 VAL C CG1 1 
ATOM   8474 C  CG2 . VAL D 2 230 ? -72.039 17.709  37.22   1    88.67  ? 226 VAL C CG2 1 
ATOM   8475 N  N   . TRP D 2 231 ? -70.792 13.361  37.589  1    82.37  ? 227 TRP C N   1 
ATOM   8476 C  CA  . TRP D 2 231 ? -69.769 12.35   37.799  1    74.3   ? 227 TRP C CA  1 
ATOM   8477 C  C   . TRP D 2 231 ? -70.353 11.209  38.624  1    77.53  ? 227 TRP C C   1 
ATOM   8478 O  O   . TRP D 2 231 ? -70.262 11.196  39.846  1    78.16  ? 227 TRP C O   1 
ATOM   8479 C  CB  . TRP D 2 231 ? -68.564 12.983  38.501  1    68.94  ? 227 TRP C CB  1 
ATOM   8480 C  CG  . TRP D 2 231 ? -67.406 12.042  38.673  1    67.51  ? 227 TRP C CG  1 
ATOM   8481 C  CD1 . TRP D 2 231 ? -67.33  10.759  38.221  1    67.66  ? 227 TRP C CD1 1 
ATOM   8482 C  CD2 . TRP D 2 231 ? -66.14  12.325  39.307  1    66.15  ? 227 TRP C CD2 1 
ATOM   8483 N  NE1 . TRP D 2 231 ? -66.109 10.224  38.529  1    63.46  ? 227 TRP C NE1 1 
ATOM   8484 C  CE2 . TRP D 2 231 ? -65.361 11.15   39.203  1    63.69  ? 227 TRP C CE2 1 
ATOM   8485 C  CE3 . TRP D 2 231 ? -65.587 13.446  39.943  1    67.31  ? 227 TRP C CE3 1 
ATOM   8486 C  CZ2 . TRP D 2 231 ? -64.065 11.071  39.716  1    62.42  ? 227 TRP C CZ2 1 
ATOM   8487 C  CZ3 . TRP D 2 231 ? -64.303 13.377  40.442  1    62.56  ? 227 TRP C CZ3 1 
ATOM   8488 C  CH2 . TRP D 2 231 ? -63.564 12.196  40.34   1    63.17  ? 227 TRP C CH2 1 
ATOM   8489 N  N   . PRO D 2 232 ? -70.982 10.2    37.992  1    85.11  ? 228 PRO C N   1 
ATOM   8490 C  CA  . PRO D 2 232 ? -71.603 9.116   38.752  1    85.91  ? 228 PRO C CA  1 
ATOM   8491 C  C   . PRO D 2 232 ? -70.547 8.403   39.595  1    82.82  ? 228 PRO C C   1 
ATOM   8492 O  O   . PRO D 2 232 ? -69.45  8.114   39.116  1    80.96  ? 228 PRO C O   1 
ATOM   8493 C  CB  . PRO D 2 232 ? -72.235 8.208   37.672  1    86.14  ? 228 PRO C CB  1 
ATOM   8494 C  CG  . PRO D 2 232 ? -72.328 9.088   36.438  1    83.58  ? 228 PRO C CG  1 
ATOM   8495 C  CD  . PRO D 2 232 ? -71.131 10.034  36.537  1    86.3   ? 228 PRO C CD  1 
ATOM   8496 N  N   . GLY D 2 233 ? -70.889 8.178   40.868  1    80.3   ? 229 GLY C N   1 
ATOM   8497 C  CA  . GLY D 2 233 ? -70.052 7.43    41.79   1    78.41  ? 229 GLY C CA  1 
ATOM   8498 C  C   . GLY D 2 233 ? -69.056 8.322   42.533  1    77.55  ? 229 GLY C C   1 
ATOM   8499 O  O   . GLY D 2 233 ? -68.303 7.822   43.362  1    78.27  ? 229 GLY C O   1 
ATOM   8500 N  N   . VAL D 2 234 ? -69.056 9.63    42.239  1    73.42  ? 230 VAL C N   1 
ATOM   8501 C  CA  . VAL D 2 234 ? -68.158 10.556  42.905  1    71.22  ? 230 VAL C CA  1 
ATOM   8502 C  C   . VAL D 2 234 ? -68.441 10.544  44.406  1    76.23  ? 230 VAL C C   1 
ATOM   8503 O  O   . VAL D 2 234 ? -67.502 10.55   45.199  1    81.51  ? 230 VAL C O   1 
ATOM   8504 C  CB  . VAL D 2 234 ? -68.179 11.999  42.363  1    70.12  ? 230 VAL C CB  1 
ATOM   8505 C  CG1 . VAL D 2 234 ? -69.521 12.689  42.593  1    70.86  ? 230 VAL C CG1 1 
ATOM   8506 C  CG2 . VAL D 2 234 ? -67.05  12.85   42.937  1    62.98  ? 230 VAL C CG2 1 
ATOM   8507 N  N   . THR D 2 235 ? -69.723 10.532  44.795  1    75.66  ? 231 THR C N   1 
ATOM   8508 C  CA  . THR D 2 235 ? -70.059 10.704  46.203  1    78.27  ? 231 THR C CA  1 
ATOM   8509 C  C   . THR D 2 235 ? -69.805 9.406   46.971  1    78.18  ? 231 THR C C   1 
ATOM   8510 O  O   . THR D 2 235 ? -69.989 9.375   48.186  1    80.06  ? 231 THR C O   1 
ATOM   8511 C  CB  . THR D 2 235 ? -71.467 11.275  46.433  1    79.21  ? 231 THR C CB  1 
ATOM   8512 O  OG1 . THR D 2 235 ? -72.433 10.261  46.168  1    80.24  ? 231 THR C OG1 1 
ATOM   8513 C  CG2 . THR D 2 235 ? -71.756 12.515  45.604  1    74.63  ? 231 THR C CG2 1 
ATOM   8514 N  N   . SER D 2 236 ? -69.423 8.356   46.256  1    79.23  ? 232 SER C N   1 
ATOM   8515 C  CA  . SER D 2 236 ? -69.143 7.063   46.922  1    83.82  ? 232 SER C CA  1 
ATOM   8516 C  C   . SER D 2 236 ? -67.628 6.878   46.98   1    84.3   ? 232 SER C C   1 
ATOM   8517 O  O   . SER D 2 236 ? -67.173 5.78    47.348  1    85.24  ? 232 SER C O   1 
ATOM   8518 C  CB  . SER D 2 236 ? -69.816 5.93    46.213  1    83.38  ? 232 SER C CB  1 
ATOM   8519 O  OG  . SER D 2 236 ? -71.107 6.312   45.762  1    85.38  ? 232 SER C OG  1 
ATOM   8520 N  N   . MET D 2 237 ? -66.889 7.93    46.642  1    83.81  ? 233 MET C N   1 
ATOM   8521 C  CA  . MET D 2 237 ? -65.413 7.8     46.589  1    82.15  ? 233 MET C CA  1 
ATOM   8522 C  C   . MET D 2 237 ? -64.839 7.86    48.008  1    84.26  ? 233 MET C C   1 
ATOM   8523 O  O   . MET D 2 237 ? -65.391 8.585   48.851  1    82.87  ? 233 MET C O   1 
ATOM   8524 C  CB  . MET D 2 237 ? -64.818 8.853   45.653  1    84.71  ? 233 MET C CB  1 
ATOM   8525 C  CG  . MET D 2 237 ? -64.59  8.294   44.276  1    85.12  ? 233 MET C CG  1 
ATOM   8526 S  SD  . MET D 2 237 ? -64.702 9.472   42.92   1    86.34  ? 233 MET C SD  1 
ATOM   8527 C  CE  . MET D 2 237 ? -65.364 8.369   41.665  1    82.88  ? 233 MET C CE  1 
ATOM   8528 N  N   . PRO D 2 238 ? -63.764 7.105   48.297  1    83.63  ? 234 PRO C N   1 
ATOM   8529 C  CA  . PRO D 2 238 ? -63.231 7.037   49.651  1    82.02  ? 234 PRO C CA  1 
ATOM   8530 C  C   . PRO D 2 238 ? -62.952 8.339   50.371  1    75.41  ? 234 PRO C C   1 
ATOM   8531 O  O   . PRO D 2 238 ? -63.206 8.431   51.581  1    74.42  ? 234 PRO C O   1 
ATOM   8532 C  CB  . PRO D 2 238 ? -61.925 6.301   49.324  1    84.16  ? 234 PRO C CB  1 
ATOM   8533 C  CG  . PRO D 2 238 ? -62.301 5.35    48.227  1    81.2   ? 234 PRO C CG  1 
ATOM   8534 C  CD  . PRO D 2 238 ? -63.062 6.285   47.326  1    81.55  ? 234 PRO C CD  1 
ATOM   8535 N  N   . ASP D 2 239 ? -62.431 9.323   49.655  1    71.12  ? 235 ASP C N   1 
ATOM   8536 C  CA  . ASP D 2 239 ? -62.024 10.579  50.257  1    74.1   ? 235 ASP C CA  1 
ATOM   8537 C  C   . ASP D 2 239 ? -63.049 11.682  49.986  1    79.38  ? 235 ASP C C   1 
ATOM   8538 O  O   . ASP D 2 239 ? -62.805 12.833  50.352  1    81.49  ? 235 ASP C O   1 
ATOM   8539 C  CB  . ASP D 2 239 ? -60.59  10.917  49.872  1    71.54  ? 235 ASP C CB  1 
ATOM   8540 C  CG  . ASP D 2 239 ? -59.541 10.011  50.499  1    71.04  ? 235 ASP C CG  1 
ATOM   8541 O  OD1 . ASP D 2 239 ? -59.767 9.622   51.654  1    75.01  ? 235 ASP C OD1 1 
ATOM   8542 O  OD2 . ASP D 2 239 ? -58.502 9.727   49.849  1    68.09  ? 235 ASP C OD2 1 
ATOM   8543 N  N   . TYR D 2 240 ? -64.186 11.326  49.357  1    80.11  ? 236 TYR C N   1 
ATOM   8544 C  CA  . TYR D 2 240 ? -65.287 12.256  49.146  1    79.39  ? 236 TYR C CA  1 
ATOM   8545 C  C   . TYR D 2 240 ? -65.887 12.58   50.515  1    86.3   ? 236 TYR C C   1 
ATOM   8546 O  O   . TYR D 2 240 ? -65.98  11.699  51.375  1    93.23  ? 236 TYR C O   1 
ATOM   8547 C  CB  . TYR D 2 240 ? -66.336 11.717  48.156  1    81.74  ? 236 TYR C CB  1 
ATOM   8548 C  CG  . TYR D 2 240 ? -67.476 12.698  47.904  1    83.41  ? 236 TYR C CG  1 
ATOM   8549 C  CD1 . TYR D 2 240 ? -68.623 12.696  48.703  1    82.19  ? 236 TYR C CD1 1 
ATOM   8550 C  CD2 . TYR D 2 240 ? -67.375 13.671  46.908  1    83.91  ? 236 TYR C CD2 1 
ATOM   8551 C  CE1 . TYR D 2 240 ? -69.641 13.618  48.504  1    84.37  ? 236 TYR C CE1 1 
ATOM   8552 C  CE2 . TYR D 2 240 ? -68.388 14.596  46.7    1    85.75  ? 236 TYR C CE2 1 
ATOM   8553 C  CZ  . TYR D 2 240 ? -69.52  14.574  47.504  1    88.33  ? 236 TYR C CZ  1 
ATOM   8554 O  OH  . TYR D 2 240 ? -70.5   15.509  47.29   1    94.87  ? 236 TYR C OH  1 
ATOM   8555 N  N   . LYS D 2 241 ? -66.287 13.847  50.703  1    84.14  ? 237 LYS C N   1 
ATOM   8556 C  CA  . LYS D 2 241 ? -66.917 14.313  51.93   1    80.89  ? 237 LYS C CA  1 
ATOM   8557 C  C   . LYS D 2 241 ? -68.228 15.014  51.557  1    76.64  ? 237 LYS C C   1 
ATOM   8558 O  O   . LYS D 2 241 ? -68.235 15.896  50.693  1    73.16  ? 237 LYS C O   1 
ATOM   8559 C  CB  . LYS D 2 241 ? -65.962 15.223  52.718  1    82.69  ? 237 LYS C CB  1 
ATOM   8560 C  CG  . LYS D 2 241 ? -64.497 14.779  52.699  1    85.46  ? 237 LYS C CG  1 
ATOM   8561 C  CD  . LYS D 2 241 ? -63.652 15.272  53.869  1    87.68  ? 237 LYS C CD  1 
ATOM   8562 C  CE  . LYS D 2 241 ? -63.344 16.743  53.783  1    90.33  ? 237 LYS C CE  1 
ATOM   8563 N  NZ  . LYS D 2 241 ? -62.898 17.28   55.071  1    85.4   ? 237 LYS C NZ  1 
ATOM   8564 N  N   . PRO D 2 242 ? -69.383 14.6    52.137  1    77.05  ? 238 PRO C N   1 
ATOM   8565 C  CA  . PRO D 2 242 ? -70.657 15.285  51.889  1    77.86  ? 238 PRO C CA  1 
ATOM   8566 C  C   . PRO D 2 242 ? -70.733 16.737  52.365  1    78.63  ? 238 PRO C C   1 
ATOM   8567 O  O   . PRO D 2 242 ? -71.678 17.444  52.022  1    80.7   ? 238 PRO C O   1 
ATOM   8568 C  CB  . PRO D 2 242 ? -71.728 14.376  52.554  1    76.97  ? 238 PRO C CB  1 
ATOM   8569 C  CG  . PRO D 2 242 ? -70.952 13.561  53.568  1    76.33  ? 238 PRO C CG  1 
ATOM   8570 C  CD  . PRO D 2 242 ? -69.539 13.412  52.999  1    76.17  ? 238 PRO C CD  1 
ATOM   8571 N  N   . SER D 2 243 ? -69.732 17.173  53.143  1    81.18  ? 239 SER C N   1 
ATOM   8572 C  CA  . SER D 2 243 ? -69.678 18.524  53.693  1    82.92  ? 239 SER C CA  1 
ATOM   8573 C  C   . SER D 2 243 ? -69.04  19.515  52.712  1    79.84  ? 239 SER C C   1 
ATOM   8574 O  O   . SER D 2 243 ? -69.161 20.725  52.878  1    85.53  ? 239 SER C O   1 
ATOM   8575 C  CB  . SER D 2 243 ? -69.025 18.542  55.06   1    81.29  ? 239 SER C CB  1 
ATOM   8576 O  OG  . SER D 2 243 ? -67.938 17.626  55.088  1    83.82  ? 239 SER C OG  1 
ATOM   8577 N  N   . PHE D 2 244 ? -68.404 19.01   51.653  1    74.25  ? 240 PHE C N   1 
ATOM   8578 C  CA  . PHE D 2 244 ? -67.813 19.865  50.633  1    72.21  ? 240 PHE C CA  1 
ATOM   8579 C  C   . PHE D 2 244 ? -68.749 21.036  50.305  1    73.31  ? 240 PHE C C   1 
ATOM   8580 O  O   . PHE D 2 244 ? -69.924 20.829  49.998  1    74.02  ? 240 PHE C O   1 
ATOM   8581 C  CB  . PHE D 2 244 ? -67.566 19.095  49.333  1    71.54  ? 240 PHE C CB  1 
ATOM   8582 C  CG  . PHE D 2 244 ? -66.336 18.197  49.3    1    75.41  ? 240 PHE C CG  1 
ATOM   8583 C  CD1 . PHE D 2 244 ? -65.174 18.553  49.977  1    77.55  ? 240 PHE C CD1 1 
ATOM   8584 C  CD2 . PHE D 2 244 ? -66.336 17.011  48.567  1    74.86  ? 240 PHE C CD2 1 
ATOM   8585 C  CE1 . PHE D 2 244 ? -64.057 17.731  49.955  1    81.05  ? 240 PHE C CE1 1 
ATOM   8586 C  CE2 . PHE D 2 244 ? -65.213 16.193  48.54   1    76.15  ? 240 PHE C CE2 1 
ATOM   8587 C  CZ  . PHE D 2 244 ? -64.075 16.553  49.234  1    77.57  ? 240 PHE C CZ  1 
ATOM   8588 N  N   . PRO D 2 245 ? -68.274 22.311  50.313  1    72.77  ? 241 PRO C N   1 
ATOM   8589 C  CA  . PRO D 2 245 ? -69.104 23.429  49.847  1    70.63  ? 241 PRO C CA  1 
ATOM   8590 C  C   . PRO D 2 245 ? -69.529 23.12   48.404  1    71.62  ? 241 PRO C C   1 
ATOM   8591 O  O   . PRO D 2 245 ? -68.854 22.362  47.701  1    66.5   ? 241 PRO C O   1 
ATOM   8592 C  CB  . PRO D 2 245 ? -68.186 24.657  49.988  1    65.01  ? 241 PRO C CB  1 
ATOM   8593 C  CG  . PRO D 2 245 ? -67.188 24.223  51.019  1    65.87  ? 241 PRO C CG  1 
ATOM   8594 C  CD  . PRO D 2 245 ? -66.92  22.746  50.7    1    67.01  ? 241 PRO C CD  1 
ATOM   8595 N  N   . LYS D 2 246 ? -70.695 23.641  47.997  1    77.42  ? 242 LYS C N   1 
ATOM   8596 C  CA  . LYS D 2 246 ? -71.249 23.45   46.655  1    77.54  ? 242 LYS C CA  1 
ATOM   8597 C  C   . LYS D 2 246 ? -71.025 24.71   45.81   1    73.82  ? 242 LYS C C   1 
ATOM   8598 O  O   . LYS D 2 246 ? -71.855 25.621  45.815  1    74.37  ? 242 LYS C O   1 
ATOM   8599 C  CB  . LYS D 2 246 ? -72.752 23.122  46.747  1    81.13  ? 242 LYS C CB  1 
ATOM   8600 C  CG  . LYS D 2 246 ? -73.208 21.831  47.433  1    84.36  ? 242 LYS C CG  1 
ATOM   8601 C  CD  . LYS D 2 246 ? -72.912 20.462  46.816  1    87.88  ? 242 LYS C CD  1 
ATOM   8602 C  CE  . LYS D 2 246 ? -73.53  19.324  47.598  1    85.13  ? 242 LYS C CE  1 
ATOM   8603 N  NZ  . LYS D 2 246 ? -72.86  19.102  48.889  1    85.37  ? 242 LYS C NZ  1 
ATOM   8604 N  N   . TRP D 2 247 ? -69.892 24.761  45.089  1    69.5   ? 243 TRP C N   1 
ATOM   8605 C  CA  . TRP D 2 247 ? -69.526 25.898  44.255  1    68.15  ? 243 TRP C CA  1 
ATOM   8606 C  C   . TRP D 2 247 ? -70.092 25.717  42.85   1    70.67  ? 243 TRP C C   1 
ATOM   8607 O  O   . TRP D 2 247 ? -70.106 24.598  42.332  1    69.83  ? 243 TRP C O   1 
ATOM   8608 C  CB  . TRP D 2 247 ? -68.001 26.078  44.186  1    62.41  ? 243 TRP C CB  1 
ATOM   8609 C  CG  . TRP D 2 247 ? -67.347 26.595  45.448  1    60.96  ? 243 TRP C CG  1 
ATOM   8610 C  CD1 . TRP D 2 247 ? -67.34  27.882  45.899  1    58.27  ? 243 TRP C CD1 1 
ATOM   8611 C  CD2 . TRP D 2 247 ? -66.54  25.836  46.38   1    58.12  ? 243 TRP C CD2 1 
ATOM   8612 N  NE1 . TRP D 2 247 ? -66.615 27.966  47.051  1    58.43  ? 243 TRP C NE1 1 
ATOM   8613 C  CE2 . TRP D 2 247 ? -66.104 26.735  47.375  1    58.62  ? 243 TRP C CE2 1 
ATOM   8614 C  CE3 . TRP D 2 247 ? -66.145 24.495  46.477  1    56.17  ? 243 TRP C CE3 1 
ATOM   8615 C  CZ2 . TRP D 2 247 ? -65.298 26.335  48.451  1    58.68  ? 243 TRP C CZ2 1 
ATOM   8616 C  CZ3 . TRP D 2 247 ? -65.358 24.1    47.542  1    58.44  ? 243 TRP C CZ3 1 
ATOM   8617 C  CH2 . TRP D 2 247 ? -64.932 25.007  48.523  1    57.29  ? 243 TRP C CH2 1 
ATOM   8618 N  N   . ALA D 2 248 ? -70.465 26.821  42.198  1    73.25  ? 244 ALA C N   1 
ATOM   8619 C  CA  . ALA D 2 248 ? -70.935 26.732  40.794  1    75.71  ? 244 ALA C CA  1 
ATOM   8620 C  C   . ALA D 2 248 ? -69.731 26.669  39.849  1    77.47  ? 244 ALA C C   1 
ATOM   8621 O  O   . ALA D 2 248 ? -68.626 27.102  40.248  1    76.52  ? 244 ALA C O   1 
ATOM   8622 C  CB  . ALA D 2 248 ? -71.827 27.909  40.472  1    74.8   ? 244 ALA C CB  1 
ATOM   8623 N  N   . ARG D 2 249 ? -69.912 26.232  38.604  1    78.69  ? 245 ARG C N   1 
ATOM   8624 C  CA  . ARG D 2 249 ? -68.769 26.26   37.654  1    77.37  ? 245 ARG C CA  1 
ATOM   8625 C  C   . ARG D 2 249 ? -68.512 27.702  37.215  1    80.15  ? 245 ARG C C   1 
ATOM   8626 O  O   . ARG D 2 249 ? -69.486 28.467  37.109  1    81.75  ? 245 ARG C O   1 
ATOM   8627 C  CB  . ARG D 2 249 ? -68.993 25.421  36.393  1    76.07  ? 245 ARG C CB  1 
ATOM   8628 C  CG  . ARG D 2 249 ? -67.765 25.301  35.503  1    74.41  ? 245 ARG C CG  1 
ATOM   8629 C  CD  . ARG D 2 249 ? -68.104 25.119  34.038  1    72.2   ? 245 ARG C CD  1 
ATOM   8630 N  NE  . ARG D 2 249 ? -68.065 23.705  33.655  1    71.85  ? 245 ARG C NE  1 
ATOM   8631 C  CZ  . ARG D 2 249 ? -66.96  23.013  33.423  1    66.46  ? 245 ARG C CZ  1 
ATOM   8632 N  NH1 . ARG D 2 249 ? -66.44  22.26   34.373  1    61.84  ? 245 ARG C NH1 1 
ATOM   8633 N  NH2 . ARG D 2 249 ? -66.386 23.07   32.237  1    61.44  ? 245 ARG C NH2 1 
ATOM   8634 N  N   . GLN D 2 250 ? -67.251 28.047  36.964  1    82.64  ? 246 GLN C N   1 
ATOM   8635 C  CA  . GLN D 2 250 ? -66.896 29.407  36.495  1    86.38  ? 246 GLN C CA  1 
ATOM   8636 C  C   . GLN D 2 250 ? -66.758 29.375  34.97   1    88.48  ? 246 GLN C C   1 
ATOM   8637 O  O   . GLN D 2 250 ? -66.161 28.419  34.448  1    90.62  ? 246 GLN C O   1 
ATOM   8638 C  CB  . GLN D 2 250 ? -65.61  29.837  37.196  1    87.56  ? 246 GLN C CB  1 
ATOM   8639 C  CG  . GLN D 2 250 ? -65.018 31.15   36.703  1    90.14  ? 246 GLN C CG  1 
ATOM   8640 C  CD  . GLN D 2 250 ? -63.879 31.634  37.572  1    94.63  ? 246 GLN C CD  1 
ATOM   8641 O  OE1 . GLN D 2 250 ? -63.196 32.615  37.259  1    103.86 ? 246 GLN C OE1 1 
ATOM   8642 N  NE2 . GLN D 2 250 ? -63.662 30.942  38.68   1    86.25  ? 246 GLN C NE2 1 
ATOM   8643 N  N   . ASP D 2 251 ? -67.303 30.38   34.289  1    92.18  ? 247 ASP C N   1 
ATOM   8644 C  CA  . ASP D 2 251 ? -67.203 30.449  32.807  1    94.09  ? 247 ASP C CA  1 
ATOM   8645 C  C   . ASP D 2 251 ? -65.73  30.445  32.404  1    90.04  ? 247 ASP C C   1 
ATOM   8646 O  O   . ASP D 2 251 ? -64.955 31.236  32.964  1    84.77  ? 247 ASP C O   1 
ATOM   8647 C  CB  . ASP D 2 251 ? -67.953 31.642  32.24   1    101.96 ? 247 ASP C CB  1 
ATOM   8648 C  CG  . ASP D 2 251 ? -69.409 31.386  31.882  1    109.9  ? 247 ASP C CG  1 
ATOM   8649 O  OD1 . ASP D 2 251 ? -69.706 30.273  31.406  1    117.13 ? 247 ASP C OD1 1 
ATOM   8650 O  OD2 . ASP D 2 251 ? -70.232 32.301  32.083  1    108.23 ? 247 ASP C OD2 1 
ATOM   8651 N  N   . PHE D 2 252 ? -65.377 29.61   31.43   1    89.17  ? 248 PHE C N   1 
ATOM   8652 C  CA  . PHE D 2 252 ? -63.967 29.503  30.971  1    89.05  ? 248 PHE C CA  1 
ATOM   8653 C  C   . PHE D 2 252 ? -63.555 30.822  30.349  1    92.15  ? 248 PHE C C   1 
ATOM   8654 O  O   . PHE D 2 252 ? -62.36  31.003  30.07   1    95.81  ? 248 PHE C O   1 
ATOM   8655 C  CB  . PHE D 2 252 ? -63.869 28.311  30.02   1    83.55  ? 248 PHE C CB  1 
ATOM   8656 C  CG  . PHE D 2 252 ? -63.581 26.986  30.709  1    86.13  ? 248 PHE C CG  1 
ATOM   8657 C  CD1 . PHE D 2 252 ? -63.983 26.761  32.02   1    89.21  ? 248 PHE C CD1 1 
ATOM   8658 C  CD2 . PHE D 2 252 ? -62.908 25.97   30.044  1    79.01  ? 248 PHE C CD2 1 
ATOM   8659 C  CE1 . PHE D 2 252 ? -63.719 25.554  32.644  1    91.76  ? 248 PHE C CE1 1 
ATOM   8660 C  CE2 . PHE D 2 252 ? -62.645 24.768  30.676  1    77.39  ? 248 PHE C CE2 1 
ATOM   8661 C  CZ  . PHE D 2 252 ? -63.051 24.561  31.97   1    83.29  ? 248 PHE C CZ  1 
ATOM   8662 N  N   . SER D 2 253 ? -64.515 31.72   30.142  1    93.7   ? 249 SER C N   1 
ATOM   8663 C  CA  . SER D 2 253 ? -64.213 33.071  29.616  1    96.83  ? 249 SER C CA  1 
ATOM   8664 C  C   . SER D 2 253 ? -63.455 33.86   30.686  1    95.84  ? 249 SER C C   1 
ATOM   8665 O  O   . SER D 2 253 ? -62.766 34.831  30.333  1    92.25  ? 249 SER C O   1 
ATOM   8666 C  CB  . SER D 2 253 ? -65.48  33.76   29.238  1    98.2   ? 249 SER C CB  1 
ATOM   8667 O  OG  . SER D 2 253 ? -66.432 32.819  28.763  1    103.15 ? 249 SER C OG  1 
ATOM   8668 N  N   . LYS D 2 254 ? -63.597 33.455  31.945  1    97.76  ? 250 LYS C N   1 
ATOM   8669 C  CA  . LYS D 2 254 ? -62.856 34.118  33.04   1    90.7   ? 250 LYS C CA  1 
ATOM   8670 C  C   . LYS D 2 254 ? -61.632 33.264  33.357  1    81.26  ? 250 LYS C C   1 
ATOM   8671 O  O   . LYS D 2 254 ? -60.582 33.841  33.676  1    79.87  ? 250 LYS C O   1 
ATOM   8672 C  CB  . LYS D 2 254 ? -63.752 34.238  34.275  1    93.41  ? 250 LYS C CB  1 
ATOM   8673 C  CG  . LYS D 2 254 ? -64.943 35.171  34.141  1    106.42 ? 250 LYS C CG  1 
ATOM   8674 C  CD  . LYS D 2 254 ? -65.803 35.223  35.397  1    115.29 ? 250 LYS C CD  1 
ATOM   8675 C  CE  . LYS D 2 254 ? -66.964 36.16   35.279  1    120.68 ? 250 LYS C CE  1 
ATOM   8676 N  NZ  . LYS D 2 254 ? -67.794 36.181  36.486  1    125.15 ? 250 LYS C NZ  1 
ATOM   8677 N  N   . VAL D 2 255 ? -61.776 31.942  33.261  1    74.06  ? 251 VAL C N   1 
ATOM   8678 C  CA  . VAL D 2 255 ? -60.659 31.012  33.592  1    70.92  ? 251 VAL C CA  1 
ATOM   8679 C  C   . VAL D 2 255 ? -59.511 31.225  32.598  1    69.31  ? 251 VAL C C   1 
ATOM   8680 O  O   . VAL D 2 255 ? -58.363 31.372  33.048  1    67.86  ? 251 VAL C O   1 
ATOM   8681 C  CB  . VAL D 2 255 ? -61.184 29.569  33.566  1    68.73  ? 251 VAL C CB  1 
ATOM   8682 C  CG1 . VAL D 2 255 ? -60.092 28.553  33.869  1    62     ? 251 VAL C CG1 1 
ATOM   8683 C  CG2 . VAL D 2 255 ? -62.364 29.392  34.511  1    68.02  ? 251 VAL C CG2 1 
ATOM   8684 N  N   . VAL D 2 256 ? -59.818 31.241  31.305  1    67.58  ? 252 VAL C N   1 
ATOM   8685 C  CA  . VAL D 2 256 ? -58.768 31.406  30.262  1    69.25  ? 252 VAL C CA  1 
ATOM   8686 C  C   . VAL D 2 256 ? -59.287 32.444  29.259  1    73.6   ? 252 VAL C C   1 
ATOM   8687 O  O   . VAL D 2 256 ? -59.818 32.05   28.202  1    74.33  ? 252 VAL C O   1 
ATOM   8688 C  CB  . VAL D 2 256 ? -58.455 30.046  29.611  1    63.81  ? 252 VAL C CB  1 
ATOM   8689 C  CG1 . VAL D 2 256 ? -57.475 30.184  28.454  1    57.82  ? 252 VAL C CG1 1 
ATOM   8690 C  CG2 . VAL D 2 256 ? -57.947 29.035  30.63   1    59.13  ? 252 VAL C CG2 1 
ATOM   8691 N  N   . PRO D 2 257 ? -59.263 33.705  29.55   1    72.12  ? 253 PRO C N   1 
ATOM   8692 C  CA  . PRO D 2 257 ? -59.807 34.739  28.665  1    71.87  ? 253 PRO C CA  1 
ATOM   8693 C  C   . PRO D 2 257 ? -59.227 34.736  27.248  1    77.59  ? 253 PRO C C   1 
ATOM   8694 O  O   . PRO D 2 257 ? -59.986 34.815  26.279  1    83.62  ? 253 PRO C O   1 
ATOM   8695 C  CB  . PRO D 2 257 ? -59.542 36.046  29.418  1    71.46  ? 253 PRO C CB  1 
ATOM   8696 C  CG  . PRO D 2 257 ? -59.412 35.606  30.863  1    73.71  ? 253 PRO C CG  1 
ATOM   8697 C  CD  . PRO D 2 257 ? -58.714 34.249  30.801  1    71.81  ? 253 PRO C CD  1 
ATOM   8698 N  N   . PRO D 2 258 ? -57.883 34.631  27.06   1    76.3   ? 254 PRO C N   1 
ATOM   8699 C  CA  . PRO D 2 258 ? -57.294 34.64   25.712  1    71.5   ? 254 PRO C CA  1 
ATOM   8700 C  C   . PRO D 2 258 ? -57.815 33.571  24.75   1    71.02  ? 254 PRO C C   1 
ATOM   8701 O  O   . PRO D 2 258 ? -57.552 33.602  23.546  1    73.15  ? 254 PRO C O   1 
ATOM   8702 C  CB  . PRO D 2 258 ? -55.772 34.459  25.961  1    69.27  ? 254 PRO C CB  1 
ATOM   8703 C  CG  . PRO D 2 258 ? -55.558 34.846  27.405  1    72.39  ? 254 PRO C CG  1 
ATOM   8704 C  CD  . PRO D 2 258 ? -56.867 34.542  28.13   1    72.7   ? 254 PRO C CD  1 
ATOM   8705 N  N   . LEU D 2 259 ? -58.512 32.583  25.303  1    69.18  ? 255 LEU C N   1 
ATOM   8706 C  CA  . LEU D 2 259 ? -58.735 31.352  24.567  1    71.88  ? 255 LEU C CA  1 
ATOM   8707 C  C   . LEU D 2 259 ? -60.025 31.459  23.761  1    75.93  ? 255 LEU C C   1 
ATOM   8708 O  O   . LEU D 2 259 ? -61.038 31.911  24.289  1    80.69  ? 255 LEU C O   1 
ATOM   8709 C  CB  . LEU D 2 259 ? -58.782 30.241  25.615  1    70.9   ? 255 LEU C CB  1 
ATOM   8710 C  CG  . LEU D 2 259 ? -58.336 28.857  25.141  1    67.49  ? 255 LEU C CG  1 
ATOM   8711 C  CD1 . LEU D 2 259 ? -56.915 28.889  24.617  1    65.49  ? 255 LEU C CD1 1 
ATOM   8712 C  CD2 . LEU D 2 259 ? -58.468 27.846  26.267  1    63.78  ? 255 LEU C CD2 1 
ATOM   8713 N  N   . ASP D 2 260 ? -59.982 31.061  22.483  1    77.1   ? 256 ASP C N   1 
ATOM   8714 C  CA  . ASP D 2 260 ? -61.167 31.11   21.63   1    80.63  ? 256 ASP C CA  1 
ATOM   8715 C  C   . ASP D 2 260 ? -62.173 30.037  22.071  1    77.33  ? 256 ASP C C   1 
ATOM   8716 O  O   . ASP D 2 260 ? -61.954 29.327  23.049  1    79.26  ? 256 ASP C O   1 
ATOM   8717 C  CB  . ASP D 2 260 ? -60.794 31.037  20.155  1    82.02  ? 256 ASP C CB  1 
ATOM   8718 C  CG  . ASP D 2 260 ? -60.243 29.688  19.69   1    85.3   ? 256 ASP C CG  1 
ATOM   8719 O  OD1 . ASP D 2 260 ? -59.291 29.184  20.328  1    75.09  ? 256 ASP C OD1 1 
ATOM   8720 O  OD2 . ASP D 2 260 ? -60.76  29.142  18.681  1    89.37  ? 256 ASP C OD2 1 
ATOM   8721 N  N   . GLU D 2 261 ? -63.274 29.904  21.331  1    74.71  ? 257 GLU C N   1 
ATOM   8722 C  CA  . GLU D 2 261 ? -64.342 28.982  21.682  1    74.83  ? 257 GLU C CA  1 
ATOM   8723 C  C   . GLU D 2 261 ? -63.914 27.522  21.515  1    70.95  ? 257 GLU C C   1 
ATOM   8724 O  O   . GLU D 2 261 ? -64.342 26.666  22.287  1    68.51  ? 257 GLU C O   1 
ATOM   8725 C  CB  . GLU D 2 261 ? -65.541 29.321  20.799  1    80.48  ? 257 GLU C CB  1 
ATOM   8726 C  CG  . GLU D 2 261 ? -66.71  28.356  20.955  1    88.03  ? 257 GLU C CG  1 
ATOM   8727 C  CD  . GLU D 2 261 ? -67.734 28.702  19.893  1    102.27 ? 257 GLU C CD  1 
ATOM   8728 O  OE1 . GLU D 2 261 ? -68.212 27.79   19.192  1    106.09 ? 257 GLU C OE1 1 
ATOM   8729 O  OE2 . GLU D 2 261 ? -68.004 29.912  19.748  1    109.8  ? 257 GLU C OE2 1 
ATOM   8730 N  N   . ASP D 2 262 ? -63.087 27.242  20.496  1    70.94  ? 258 ASP C N   1 
ATOM   8731 C  CA  . ASP D 2 262 ? -62.484 25.93   20.282  1    69.64  ? 258 ASP C CA  1 
ATOM   8732 C  C   . ASP D 2 262 ? -61.593 25.507  21.459  1    66.97  ? 258 ASP C C   1 
ATOM   8733 O  O   . ASP D 2 262 ? -61.723 24.396  21.972  1    68.87  ? 258 ASP C O   1 
ATOM   8734 C  CB  . ASP D 2 262 ? -61.773 25.865  18.938  1    69.78  ? 258 ASP C CB  1 
ATOM   8735 C  CG  . ASP D 2 262 ? -62.673 25.592  17.738  1    73.82  ? 258 ASP C CG  1 
ATOM   8736 O  OD1 . ASP D 2 262 ? -63.853 25.283  17.958  1    75.31  ? 258 ASP C OD1 1 
ATOM   8737 O  OD2 . ASP D 2 262 ? -62.191 25.687  16.59   1    72.73  ? 258 ASP C OD2 1 
ATOM   8738 N  N   . GLY D 2 263 ? -60.667 26.379  21.878  1    62.09  ? 259 GLY C N   1 
ATOM   8739 C  CA  . GLY D 2 263 ? -59.791 26.075  22.996  1    58.59  ? 259 GLY C CA  1 
ATOM   8740 C  C   . GLY D 2 263 ? -60.578 25.792  24.274  1    59.22  ? 259 GLY C C   1 
ATOM   8741 O  O   . GLY D 2 263 ? -60.262 24.843  24.994  1    58.62  ? 259 GLY C O   1 
ATOM   8742 N  N   . ARG D 2 264 ? -61.6   26.615  24.542  1    58.18  ? 260 ARG C N   1 
ATOM   8743 C  CA  . ARG D 2 264 ? -62.482 26.445  25.695  1    59.23  ? 260 ARG C CA  1 
ATOM   8744 C  C   . ARG D 2 264 ? -63.124 25.052  25.694  1    59.1   ? 260 ARG C C   1 
ATOM   8745 O  O   . ARG D 2 264 ? -63.111 24.35   26.7    1    59.01  ? 260 ARG C O   1 
ATOM   8746 C  CB  . ARG D 2 264 ? -63.476 27.613  25.756  1    61.23  ? 260 ARG C CB  1 
ATOM   8747 C  CG  . ARG D 2 264 ? -62.823 28.89   26.288  1    63.31  ? 260 ARG C CG  1 
ATOM   8748 C  CD  . ARG D 2 264 ? -63.498 30.24   26.06   1    66.32  ? 260 ARG C CD  1 
ATOM   8749 N  NE  . ARG D 2 264 ? -64.922 30.126  25.72   1    72.58  ? 260 ARG C NE  1 
ATOM   8750 C  CZ  . ARG D 2 264 ? -65.528 30.686  24.662  1    77.08  ? 260 ARG C CZ  1 
ATOM   8751 N  NH1 . ARG D 2 264 ? -64.958 31.666  23.974  1    73.13  ? 260 ARG C NH1 1 
ATOM   8752 N  NH2 . ARG D 2 264 ? -66.739 30.292  24.306  1    79.38  ? 260 ARG C NH2 1 
ATOM   8753 N  N   . SER D 2 265 ? -63.67  24.648  24.547  1    58.89  ? 261 SER C N   1 
ATOM   8754 C  CA  . SER D 2 265 ? -64.262 23.336  24.35   1    56.21  ? 261 SER C CA  1 
ATOM   8755 C  C   . SER D 2 265 ? -63.242 22.219  24.614  1    55.49  ? 261 SER C C   1 
ATOM   8756 O  O   . SER D 2 265 ? -63.493 21.292  25.389  1    56.12  ? 261 SER C O   1 
ATOM   8757 C  CB  . SER D 2 265 ? -64.803 23.285  22.948  1    57.52  ? 261 SER C CB  1 
ATOM   8758 O  OG  . SER D 2 265 ? -65.232 21.984  22.583  1    56.23  ? 261 SER C OG  1 
ATOM   8759 N  N   . LEU D 2 266 ? -62.072 22.297  23.979  1    52.62  ? 262 LEU C N   1 
ATOM   8760 C  CA  . LEU D 2 266 ? -61.065 21.27   24.205  1    54.2   ? 262 LEU C CA  1 
ATOM   8761 C  C   . LEU D 2 266 ? -60.56  21.275  25.664  1    57.8   ? 262 LEU C C   1 
ATOM   8762 O  O   . LEU D 2 266 ? -60.289 20.22   26.261  1    54.42  ? 262 LEU C O   1 
ATOM   8763 C  CB  . LEU D 2 266 ? -59.907 21.417  23.225  1    49.74  ? 262 LEU C CB  1 
ATOM   8764 C  CG  . LEU D 2 266 ? -58.712 20.501  23.521  1    48.18  ? 262 LEU C CG  1 
ATOM   8765 C  CD1 . LEU D 2 266 ? -59.07  19.024  23.312  1    44.62  ? 262 LEU C CD1 1 
ATOM   8766 C  CD2 . LEU D 2 266 ? -57.478 20.91   22.726  1    45.61  ? 262 LEU C CD2 1 
ATOM   8767 N  N   . LEU D 2 267 ? -60.403 22.471  26.248  1    55.11  ? 263 LEU C N   1 
ATOM   8768 C  CA  . LEU D 2 267 ? -59.926 22.547  27.616  1    50.06  ? 263 LEU C CA  1 
ATOM   8769 C  C   . LEU D 2 267 ? -60.941 21.871  28.533  1    50.73  ? 263 LEU C C   1 
ATOM   8770 O  O   . LEU D 2 267 ? -60.549 21.16   29.45   1    51.39  ? 263 LEU C O   1 
ATOM   8771 C  CB  . LEU D 2 267 ? -59.586 23.972  28.053  1    48.21  ? 263 LEU C CB  1 
ATOM   8772 C  CG  . LEU D 2 267 ? -59.27  24.165  29.538  1    45.69  ? 263 LEU C CG  1 
ATOM   8773 C  CD1 . LEU D 2 267 ? -58.122 23.243  29.961  1    47.55  ? 263 LEU C CD1 1 
ATOM   8774 C  CD2 . LEU D 2 267 ? -58.94  25.619  29.863  1    43.55  ? 263 LEU C CD2 1 
ATOM   8775 N  N   . SER D 2 268 ? -62.239 22.041  28.256  1    51.4   ? 264 SER C N   1 
ATOM   8776 C  CA  . SER D 2 268 ? -63.241 21.55   29.191  1    54.51  ? 264 SER C CA  1 
ATOM   8777 C  C   . SER D 2 268 ? -63.355 20.026  29.122  1    55.07  ? 264 SER C C   1 
ATOM   8778 O  O   . SER D 2 268 ? -63.516 19.37   30.149  1    55.44  ? 264 SER C O   1 
ATOM   8779 C  CB  . SER D 2 268 ? -64.567 22.243  29.027  1    56.8   ? 264 SER C CB  1 
ATOM   8780 O  OG  . SER D 2 268 ? -65.115 21.927  27.762  1    66.02  ? 264 SER C OG  1 
ATOM   8781 N  N   . GLN D 2 269 ? -63.237 19.458  27.916  1    54.52  ? 265 GLN C N   1 
ATOM   8782 C  CA  . GLN D 2 269 ? -63.24  18.011  27.772  1    51.93  ? 265 GLN C CA  1 
ATOM   8783 C  C   . GLN D 2 269 ? -62.005 17.394  28.424  1    52.2   ? 265 GLN C C   1 
ATOM   8784 O  O   . GLN D 2 269 ? -62.05  16.256  28.911  1    55.34  ? 265 GLN C O   1 
ATOM   8785 C  CB  . GLN D 2 269 ? -63.3   17.637  26.3    1    49.85  ? 265 GLN C CB  1 
ATOM   8786 C  CG  . GLN D 2 269 ? -64.585 18.092  25.628  1    51.07  ? 265 GLN C CG  1 
ATOM   8787 C  CD  . GLN D 2 269 ? -64.585 17.778  24.148  1    51.91  ? 265 GLN C CD  1 
ATOM   8788 O  OE1 . GLN D 2 269 ? -64.71  18.676  23.317  1    52.3   ? 265 GLN C OE1 1 
ATOM   8789 N  NE2 . GLN D 2 269 ? -64.443 16.506  23.795  1    49.79  ? 265 GLN C NE2 1 
ATOM   8790 N  N   . MET D 2 270 ? -60.901 18.147  28.436  1    49.08  ? 266 MET C N   1 
ATOM   8791 C  CA  . MET D 2 270 ? -59.679 17.653  29.059  1    48.81  ? 266 MET C CA  1 
ATOM   8792 C  C   . MET D 2 270 ? -59.766 17.671  30.584  1    48.78  ? 266 MET C C   1 
ATOM   8793 O  O   . MET D 2 270 ? -58.988 16.998  31.253  1    46.16  ? 266 MET C O   1 
ATOM   8794 C  CB  . MET D 2 270 ? -58.47  18.476  28.624  1    45.49  ? 266 MET C CB  1 
ATOM   8795 C  CG  . MET D 2 270 ? -57.963 18.011  27.29   1    46.13  ? 266 MET C CG  1 
ATOM   8796 S  SD  . MET D 2 270 ? -56.638 19.051  26.662  1    50.14  ? 266 MET C SD  1 
ATOM   8797 C  CE  . MET D 2 270 ? -55.174 18.133  27.173  1    43.2   ? 266 MET C CE  1 
ATOM   8798 N  N   . LEU D 2 271 ? -60.712 18.448  31.121  1    48.49  ? 267 LEU C N   1 
ATOM   8799 C  CA  . LEU D 2 271 ? -60.858 18.589  32.554  1    48.24  ? 267 LEU C CA  1 
ATOM   8800 C  C   . LEU D 2 271 ? -62.22  18.065  33.021  1    49.51  ? 267 LEU C C   1 
ATOM   8801 O  O   . LEU D 2 271 ? -62.688 18.442  34.094  1    48.66  ? 267 LEU C O   1 
ATOM   8802 C  CB  . LEU D 2 271 ? -60.613 20.056  32.922  1    47.16  ? 267 LEU C CB  1 
ATOM   8803 C  CG  . LEU D 2 271 ? -59.191 20.593  32.688  1    45.9   ? 267 LEU C CG  1 
ATOM   8804 C  CD1 . LEU D 2 271 ? -59.085 22.024  33.202  1    46.62  ? 267 LEU C CD1 1 
ATOM   8805 C  CD2 . LEU D 2 271 ? -58.09  19.712  33.298  1    40.28  ? 267 LEU C CD2 1 
ATOM   8806 N  N   . HIS D 2 272 ? -62.832 17.147  32.261  1    51.44  ? 268 HIS C N   1 
ATOM   8807 C  CA  . HIS D 2 272 ? -64.029 16.489  32.765  1    56.57  ? 268 HIS C CA  1 
ATOM   8808 C  C   . HIS D 2 272 ? -63.693 15.787  34.087  1    58.3   ? 268 HIS C C   1 
ATOM   8809 O  O   . HIS D 2 272 ? -62.58  15.266  34.273  1    54.66  ? 268 HIS C O   1 
ATOM   8810 C  CB  . HIS D 2 272 ? -64.679 15.618  31.683  1    62.13  ? 268 HIS C CB  1 
ATOM   8811 C  CG  . HIS D 2 272 ? -66.112 15.293  31.961  1    79.6   ? 268 HIS C CG  1 
ATOM   8812 N  ND1 . HIS D 2 272 ? -67.135 15.674  31.116  1    91.76  ? 268 HIS C ND1 1 
ATOM   8813 C  CD2 . HIS D 2 272 ? -66.713 14.699  33.001  1    83.75  ? 268 HIS C CD2 1 
ATOM   8814 C  CE1 . HIS D 2 272 ? -68.304 15.294  31.625  1    95.99  ? 268 HIS C CE1 1 
ATOM   8815 N  NE2 . HIS D 2 272 ? -68.065 14.718  32.78   1    92.96  ? 268 HIS C NE2 1 
ATOM   8816 N  N   . TYR D 2 273 ? -64.651 15.828  35.025  1    57.61  ? 269 TYR C N   1 
ATOM   8817 C  CA  . TYR D 2 273 ? -64.489 15.189  36.323  1    56.13  ? 269 TYR C CA  1 
ATOM   8818 C  C   . TYR D 2 273 ? -64.409 13.672  36.18   1    55.52  ? 269 TYR C C   1 
ATOM   8819 O  O   . TYR D 2 273 ? -63.457 13.057  36.66   1    53.55  ? 269 TYR C O   1 
ATOM   8820 C  CB  . TYR D 2 273 ? -65.666 15.551  37.219  1    55.33  ? 269 TYR C CB  1 
ATOM   8821 C  CG  . TYR D 2 273 ? -65.412 16.83   37.988  1    57.02  ? 269 TYR C CG  1 
ATOM   8822 C  CD1 . TYR D 2 273 ? -64.424 16.875  38.966  1    55.31  ? 269 TYR C CD1 1 
ATOM   8823 C  CD2 . TYR D 2 273 ? -66.164 17.98   37.747  1    58.4   ? 269 TYR C CD2 1 
ATOM   8824 C  CE1 . TYR D 2 273 ? -64.179 18.042  39.674  1    55.79  ? 269 TYR C CE1 1 
ATOM   8825 C  CE2 . TYR D 2 273 ? -65.927 19.152  38.458  1    58.4   ? 269 TYR C CE2 1 
ATOM   8826 C  CZ  . TYR D 2 273 ? -64.931 19.184  39.424  1    57.04  ? 269 TYR C CZ  1 
ATOM   8827 O  OH  . TYR D 2 273 ? -64.702 20.324  40.148  1    56.02  ? 269 TYR C OH  1 
ATOM   8828 N  N   . ASP D 2 274 ? -65.433 13.092  35.539  1    55.36  ? 270 ASP C N   1 
ATOM   8829 C  CA  . ASP D 2 274 ? -65.535 11.66   35.305  1    56.33  ? 270 ASP C CA  1 
ATOM   8830 C  C   . ASP D 2 274 ? -64.377 11.196  34.419  1    57.43  ? 270 ASP C C   1 
ATOM   8831 O  O   . ASP D 2 274 ? -64.257 11.62   33.27   1    56.39  ? 270 ASP C O   1 
ATOM   8832 C  CB  . ASP D 2 274 ? -66.872 11.334  34.669  1    56.28  ? 270 ASP C CB  1 
ATOM   8833 C  CG  . ASP D 2 274 ? -67.233 9.865   34.6    1    59.33  ? 270 ASP C CG  1 
ATOM   8834 O  OD1 . ASP D 2 274 ? -66.293 9.018   34.627  1    56.74  ? 270 ASP C OD1 1 
ATOM   8835 O  OD2 . ASP D 2 274 ? -68.461 9.599   34.532  1    63.49  ? 270 ASP C OD2 1 
ATOM   8836 N  N   . PRO D 2 275 ? -63.47  10.319  34.914  1    58.08  ? 271 PRO C N   1 
ATOM   8837 C  CA  . PRO D 2 275 ? -62.361 9.842   34.086  1    53.78  ? 271 PRO C CA  1 
ATOM   8838 C  C   . PRO D 2 275 ? -62.831 9.161   32.803  1    56.88  ? 271 PRO C C   1 
ATOM   8839 O  O   . PRO D 2 275 ? -62.078 9.149   31.835  1    57.57  ? 271 PRO C O   1 
ATOM   8840 C  CB  . PRO D 2 275 ? -61.627 8.868   35.014  1    53.61  ? 271 PRO C CB  1 
ATOM   8841 C  CG  . PRO D 2 275 ? -62.005 9.309   36.406  1    55.26  ? 271 PRO C CG  1 
ATOM   8842 C  CD  . PRO D 2 275 ? -63.432 9.791   36.294  1    56.08  ? 271 PRO C CD  1 
ATOM   8843 N  N   . ASN D 2 276 ? -64.062 8.603   32.809  1    58.82  ? 272 ASN C N   1 
ATOM   8844 C  CA  . ASN D 2 276 ? -64.584 7.811   31.702  1    58.14  ? 272 ASN C CA  1 
ATOM   8845 C  C   . ASN D 2 276 ? -65.046 8.704   30.557  1    57.74  ? 272 ASN C C   1 
ATOM   8846 O  O   . ASN D 2 276 ? -65.058 8.286   29.398  1    57.18  ? 272 ASN C O   1 
ATOM   8847 C  CB  . ASN D 2 276 ? -65.753 6.926   32.113  1    63.38  ? 272 ASN C CB  1 
ATOM   8848 C  CG  . ASN D 2 276 ? -65.373 5.848   33.105  1    66.58  ? 272 ASN C CG  1 
ATOM   8849 O  OD1 . ASN D 2 276 ? -64.377 5.137   32.922  1    65.3   ? 272 ASN C OD1 1 
ATOM   8850 N  ND2 . ASN D 2 276 ? -66.153 5.71    34.166  1    67.17  ? 272 ASN C ND2 1 
ATOM   8851 N  N   . LYS D 2 277 ? -65.427 9.936   30.898  1    59.15  ? 273 LYS C N   1 
ATOM   8852 C  CA  . LYS D 2 277 ? -65.982 10.884  29.947  1    60.66  ? 273 LYS C CA  1 
ATOM   8853 C  C   . LYS D 2 277 ? -64.912 11.87   29.478  1    56.19  ? 273 LYS C C   1 
ATOM   8854 O  O   . LYS D 2 277 ? -65.148 12.592  28.517  1    53.57  ? 273 LYS C O   1 
ATOM   8855 C  CB  . LYS D 2 277 ? -67.212 11.549  30.566  1    67.07  ? 273 LYS C CB  1 
ATOM   8856 C  CG  . LYS D 2 277 ? -68.291 10.495  30.86   1    80.81  ? 273 LYS C CG  1 
ATOM   8857 C  CD  . LYS D 2 277 ? -69.722 10.894  30.527  1    87.01  ? 273 LYS C CD  1 
ATOM   8858 C  CE  . LYS D 2 277 ? -70.26  11.968  31.442  1    92.21  ? 273 LYS C CE  1 
ATOM   8859 N  NZ  . LYS D 2 277 ? -71.403 12.657  30.842  1    97.86  ? 273 LYS C NZ  1 
ATOM   8860 N  N   . ARG D 2 278 ? -63.749 11.898  30.157  1    52.92  ? 274 ARG C N   1 
ATOM   8861 C  CA  . ARG D 2 278 ? -62.623 12.753  29.801  1    47.68  ? 274 ARG C CA  1 
ATOM   8862 C  C   . ARG D 2 278 ? -62.055 12.298  28.459  1    47.71  ? 274 ARG C C   1 
ATOM   8863 O  O   . ARG D 2 278 ? -61.944 11.104  28.203  1    49.04  ? 274 ARG C O   1 
ATOM   8864 C  CB  . ARG D 2 278 ? -61.573 12.704  30.913  1    45.27  ? 274 ARG C CB  1 
ATOM   8865 C  CG  . ARG D 2 278 ? -60.588 13.864  30.943  1    44.55  ? 274 ARG C CG  1 
ATOM   8866 C  CD  . ARG D 2 278 ? -59.647 13.666  32.122  1    44.62  ? 274 ARG C CD  1 
ATOM   8867 N  NE  . ARG D 2 278 ? -60.373 13.667  33.392  1    49.81  ? 274 ARG C NE  1 
ATOM   8868 C  CZ  . ARG D 2 278 ? -60.009 13.103  34.538  1    49.54  ? 274 ARG C CZ  1 
ATOM   8869 N  NH1 . ARG D 2 278 ? -58.874 12.433  34.635  1    46.2   ? 274 ARG C NH1 1 
ATOM   8870 N  NH2 . ARG D 2 278 ? -60.81  13.198  35.589  1    49.26  ? 274 ARG C NH2 1 
ATOM   8871 N  N   . ILE D 2 279 ? -61.696 13.259  27.604  1    46.08  ? 275 ILE C N   1 
ATOM   8872 C  CA  . ILE D 2 279 ? -61.306 12.979  26.235  1    45.82  ? 275 ILE C CA  1 
ATOM   8873 C  C   . ILE D 2 279 ? -59.961 12.261  26.253  1    48.1   ? 275 ILE C C   1 
ATOM   8874 O  O   . ILE D 2 279 ? -59.168 12.437  27.179  1    50.19  ? 275 ILE C O   1 
ATOM   8875 C  CB  . ILE D 2 279 ? -61.236 14.297  25.45   1    47.39  ? 275 ILE C CB  1 
ATOM   8876 C  CG1 . ILE D 2 279 ? -61.215 14.06   23.94   1    49.26  ? 275 ILE C CG1 1 
ATOM   8877 C  CG2 . ILE D 2 279 ? -60.076 15.182  25.934  1    46.5   ? 275 ILE C CG2 1 
ATOM   8878 C  CD1 . ILE D 2 279 ? -61.166 15.333  23.109  1    49.32  ? 275 ILE C CD1 1 
ATOM   8879 N  N   . SER D 2 280 ? -59.709 11.448  25.224  1    48.9   ? 276 SER C N   1 
ATOM   8880 C  CA  . SER D 2 280 ? -58.446 10.738  25.103  1    48.84  ? 276 SER C CA  1 
ATOM   8881 C  C   . SER D 2 280 ? -57.485 11.601  24.284  1    50.51  ? 276 SER C C   1 
ATOM   8882 O  O   . SER D 2 280 ? -57.931 12.545  23.634  1    51.23  ? 276 SER C O   1 
ATOM   8883 C  CB  . SER D 2 280 ? -58.662 9.424   24.439  1    47.91  ? 276 SER C CB  1 
ATOM   8884 O  OG  . SER D 2 280 ? -59.134 9.672   23.118  1    55.41  ? 276 SER C OG  1 
ATOM   8885 N  N   . ALA D 2 281 ? -56.182 11.269  24.312  1    47.26  ? 277 ALA C N   1 
ATOM   8886 C  CA  . ALA D 2 281 ? -55.199 11.944  23.479  1    44.58  ? 277 ALA C CA  1 
ATOM   8887 C  C   . ALA D 2 281 ? -55.538 11.74   21.993  1    45.14  ? 277 ALA C C   1 
ATOM   8888 O  O   . ALA D 2 281 ? -55.564 12.714  21.245  1    46.44  ? 277 ALA C O   1 
ATOM   8889 C  CB  . ALA D 2 281 ? -53.794 11.508  23.855  1    38.33  ? 277 ALA C CB  1 
ATOM   8890 N  N   . LYS D 2 282 ? -55.853 10.498  21.577  1    46.15  ? 278 LYS C N   1 
ATOM   8891 C  CA  . LYS D 2 282 ? -56.294 10.207  20.214  1    48.77  ? 278 LYS C CA  1 
ATOM   8892 C  C   . LYS D 2 282 ? -57.423 11.143  19.787  1    52.43  ? 278 LYS C C   1 
ATOM   8893 O  O   . LYS D 2 282 ? -57.337 11.777  18.736  1    52.74  ? 278 LYS C O   1 
ATOM   8894 C  CB  . LYS D 2 282 ? -56.886 8.805   20.047  1    51.03  ? 278 LYS C CB  1 
ATOM   8895 C  CG  . LYS D 2 282 ? -55.909 7.718   19.656  1    55.82  ? 278 LYS C CG  1 
ATOM   8896 C  CD  . LYS D 2 282 ? -56.582 6.377   19.374  1    59.52  ? 278 LYS C CD  1 
ATOM   8897 C  CE  . LYS D 2 282 ? -55.505 5.37    19.043  1    69.06  ? 278 LYS C CE  1 
ATOM   8898 N  NZ  . LYS D 2 282 ? -55.863 3.943   19.13   1    75.26  ? 278 LYS C NZ  1 
ATOM   8899 N  N   . ALA D 2 283 ? -58.475 11.22   20.614  1    55.62  ? 279 ALA C N   1 
ATOM   8900 C  CA  . ALA D 2 283 ? -59.658 12.015  20.304  1    58.59  ? 279 ALA C CA  1 
ATOM   8901 C  C   . ALA D 2 283 ? -59.302 13.504  20.21   1    58.24  ? 279 ALA C C   1 
ATOM   8902 O  O   . ALA D 2 283 ? -59.627 14.163  19.219  1    57.74  ? 279 ALA C O   1 
ATOM   8903 C  CB  . ALA D 2 283 ? -60.778 11.743  21.303  1    55.15  ? 279 ALA C CB  1 
ATOM   8904 N  N   . ALA D 2 284 ? -58.607 14.016  21.237  1    53.81  ? 280 ALA C N   1 
ATOM   8905 C  CA  . ALA D 2 284 ? -58.175 15.403  21.28   1    53.14  ? 280 ALA C CA  1 
ATOM   8906 C  C   . ALA D 2 284 ? -57.466 15.824  19.991  1    54.93  ? 280 ALA C C   1 
ATOM   8907 O  O   . ALA D 2 284 ? -57.666 16.948  19.534  1    58.27  ? 280 ALA C O   1 
ATOM   8908 C  CB  . ALA D 2 284 ? -57.299 15.62   22.477  1    50.62  ? 280 ALA C CB  1 
ATOM   8909 N  N   . LEU D 2 285 ? -56.649 14.92   19.415  1    52.4   ? 281 LEU C N   1 
ATOM   8910 C  CA  . LEU D 2 285 ? -55.913 15.172  18.179  1    53.18  ? 281 LEU C CA  1 
ATOM   8911 C  C   . LEU D 2 285 ? -56.823 15.545  16.993  1    56.04  ? 281 LEU C C   1 
ATOM   8912 O  O   . LEU D 2 285 ? -56.389 16.208  16.046  1    56.5   ? 281 LEU C O   1 
ATOM   8913 C  CB  . LEU D 2 285 ? -55.062 13.939  17.892  1    52.46  ? 281 LEU C CB  1 
ATOM   8914 C  CG  . LEU D 2 285 ? -53.771 13.832  18.71   1    53.31  ? 281 LEU C CG  1 
ATOM   8915 C  CD1 . LEU D 2 285 ? -52.968 12.606  18.301  1    49.78  ? 281 LEU C CD1 1 
ATOM   8916 C  CD2 . LEU D 2 285 ? -52.942 15.11   18.581  1    49.79  ? 281 LEU C CD2 1 
ATOM   8917 N  N   . ALA D 2 286 ? -58.096 15.124  17.047  1    56.25  ? 282 ALA C N   1 
ATOM   8918 C  CA  . ALA D 2 286 ? -59.081 15.446  16.025  1    54.04  ? 282 ALA C CA  1 
ATOM   8919 C  C   . ALA D 2 286 ? -59.893 16.709  16.362  1    56.45  ? 282 ALA C C   1 
ATOM   8920 O  O   . ALA D 2 286 ? -60.676 17.145  15.53   1    58.98  ? 282 ALA C O   1 
ATOM   8921 C  CB  . ALA D 2 286 ? -59.975 14.253  15.815  1    50.07  ? 282 ALA C CB  1 
ATOM   8922 N  N   . HIS D 2 287 ? -59.714 17.321  17.548  1    56.33  ? 283 HIS C N   1 
ATOM   8923 C  CA  . HIS D 2 287 ? -60.566 18.437  17.949  1    56.38  ? 283 HIS C CA  1 
ATOM   8924 C  C   . HIS D 2 287 ? -60.439 19.6    16.956  1    58.54  ? 283 HIS C C   1 
ATOM   8925 O  O   . HIS D 2 287 ? -59.369 19.814  16.39   1    61.17  ? 283 HIS C O   1 
ATOM   8926 C  CB  . HIS D 2 287 ? -60.287 18.815  19.409  1    54.26  ? 283 HIS C CB  1 
ATOM   8927 C  CG  . HIS D 2 287 ? -61.285 19.766  19.983  1    59.27  ? 283 HIS C CG  1 
ATOM   8928 N  ND1 . HIS D 2 287 ? -61.343 21.102  19.637  1    60.82  ? 283 HIS C ND1 1 
ATOM   8929 C  CD2 . HIS D 2 287 ? -62.296 19.581  20.855  1    59.9   ? 283 HIS C CD2 1 
ATOM   8930 C  CE1 . HIS D 2 287 ? -62.341 21.694  20.288  1    60.26  ? 283 HIS C CE1 1 
ATOM   8931 N  NE2 . HIS D 2 287 ? -62.933 20.792  21.036  1    58.82  ? 283 HIS C NE2 1 
ATOM   8932 N  N   . PRO D 2 288 ? -61.521 20.357  16.649  1    59.83  ? 284 PRO C N   1 
ATOM   8933 C  CA  . PRO D 2 288 ? -61.427 21.544  15.785  1    62.39  ? 284 PRO C CA  1 
ATOM   8934 C  C   . PRO D 2 288 ? -60.362 22.58   16.143  1    59.51  ? 284 PRO C C   1 
ATOM   8935 O  O   . PRO D 2 288 ? -59.969 23.396  15.319  1    61.38  ? 284 PRO C O   1 
ATOM   8936 C  CB  . PRO D 2 288 ? -62.852 22.154  15.826  1    60.08  ? 284 PRO C CB  1 
ATOM   8937 C  CG  . PRO D 2 288 ? -63.714 20.942  16.038  1    60.65  ? 284 PRO C CG  1 
ATOM   8938 C  CD  . PRO D 2 288 ? -62.915 20.077  17.028  1    60.86  ? 284 PRO C CD  1 
ATOM   8939 N  N   . PHE D 2 289 ? -59.889 22.553  17.381  1    56.79  ? 285 PHE C N   1 
ATOM   8940 C  CA  . PHE D 2 289 ? -58.843 23.481  17.774  1    58.39  ? 285 PHE C CA  1 
ATOM   8941 C  C   . PHE D 2 289 ? -57.614 23.305  16.881  1    56.91  ? 285 PHE C C   1 
ATOM   8942 O  O   . PHE D 2 289 ? -56.981 24.295  16.537  1    56.68  ? 285 PHE C O   1 
ATOM   8943 C  CB  . PHE D 2 289 ? -58.552 23.291  19.263  1    56.85  ? 285 PHE C CB  1 
ATOM   8944 C  CG  . PHE D 2 289 ? -57.541 24.238  19.88   1    54.81  ? 285 PHE C CG  1 
ATOM   8945 C  CD1 . PHE D 2 289 ? -57.86  25.578  20.056  1    56.86  ? 285 PHE C CD1 1 
ATOM   8946 C  CD2 . PHE D 2 289 ? -56.326 23.763  20.359  1    54.79  ? 285 PHE C CD2 1 
ATOM   8947 C  CE1 . PHE D 2 289 ? -56.977 26.444  20.671  1    56.59  ? 285 PHE C CE1 1 
ATOM   8948 C  CE2 . PHE D 2 289 ? -55.436 24.634  20.968  1    57.6   ? 285 PHE C CE2 1 
ATOM   8949 C  CZ  . PHE D 2 289 ? -55.771 25.967  21.128  1    59.91  ? 285 PHE C CZ  1 
ATOM   8950 N  N   . PHE D 2 290 ? -57.314 22.063  16.479  1    55.35  ? 286 PHE C N   1 
ATOM   8951 C  CA  . PHE D 2 290 ? -56.094 21.754  15.74   1    58.09  ? 286 PHE C CA  1 
ATOM   8952 C  C   . PHE D 2 290 ? -56.259 21.857  14.212  1    61.63  ? 286 PHE C C   1 
ATOM   8953 O  O   . PHE D 2 290 ? -55.306 21.638  13.463  1    59.93  ? 286 PHE C O   1 
ATOM   8954 C  CB  . PHE D 2 290 ? -55.528 20.402  16.186  1    53.18  ? 286 PHE C CB  1 
ATOM   8955 C  CG  . PHE D 2 290 ? -55.231 20.331  17.673  1    53.4   ? 286 PHE C CG  1 
ATOM   8956 C  CD1 . PHE D 2 290 ? -54.297 21.19   18.251  1    50.96  ? 286 PHE C CD1 1 
ATOM   8957 C  CD2 . PHE D 2 290 ? -55.878 19.4    18.482  1    54.31  ? 286 PHE C CD2 1 
ATOM   8958 C  CE1 . PHE D 2 290 ? -54.026 21.12   19.604  1    52.62  ? 286 PHE C CE1 1 
ATOM   8959 C  CE2 . PHE D 2 290 ? -55.602 19.338  19.845  1    53.11  ? 286 PHE C CE2 1 
ATOM   8960 C  CZ  . PHE D 2 290 ? -54.667 20.191  20.403  1    52.55  ? 286 PHE C CZ  1 
ATOM   8961 N  N   . GLN D 2 291 ? -57.292 22.175  13.648  1    63.92  ? 287 GLN C N   1 
ATOM   8962 C  CA  . GLN D 2 291 ? -57.423 22.206  12.173  1    68.44  ? 287 GLN C CA  1 
ATOM   8963 C  C   . GLN D 2 291 ? -56.405 23.172  11.55   1    68.49  ? 287 GLN C C   1 
ATOM   8964 O  O   . GLN D 2 291 ? -55.915 22.856  10.457  1    68.77  ? 287 GLN C O   1 
ATOM   8965 C  CB  . GLN D 2 291 ? -58.865 22.57   11.834  1    73.79  ? 287 GLN C CB  1 
ATOM   8966 C  CG  . GLN D 2 291 ? -59.851 21.444  12.126  1    83.5   ? 287 GLN C CG  1 
ATOM   8967 C  CD  . GLN D 2 291 ? -61.297 21.834  11.922  1    89.39  ? 287 GLN C CD  1 
ATOM   8968 O  OE1 . GLN D 2 291 ? -61.616 22.971  11.558  1    88.23  ? 287 GLN C OE1 1 
ATOM   8969 N  NE2 . GLN D 2 291 ? -62.191 20.886  12.159  1    85.75  ? 287 GLN C NE2 1 
ATOM   8970 N  N   . ASP D 2 292 ? -56.142 24.373  12.256  1    67.4   ? 288 ASP C N   1 
ATOM   8971 C  CA  . ASP D 2 292 ? -55.201 25.286  11.614  1    67.36  ? 288 ASP C CA  1 
ATOM   8972 C  C   . ASP D 2 292 ? -53.793 25.166  12.212  1    66.36  ? 288 ASP C C   1 
ATOM   8973 O  O   . ASP D 2 292 ? -53.006 26.107  12.113  1    67.93  ? 288 ASP C O   1 
ATOM   8974 C  CB  . ASP D 2 292 ? -55.742 26.713  11.629  1    71.1   ? 288 ASP C CB  1 
ATOM   8975 C  CG  . ASP D 2 292 ? -56.005 27.32   13.009  1    71.71  ? 288 ASP C CG  1 
ATOM   8976 O  OD1 . ASP D 2 292 ? -55.439 26.825  14.002  1    67.82  ? 288 ASP C OD1 1 
ATOM   8977 O  OD2 . ASP D 2 292 ? -56.765 28.301  13.088  1    72.44  ? 288 ASP C OD2 1 
ATOM   8978 N  N   . VAL D 2 293 ? -53.462 24.026  12.839  1    61.37  ? 289 VAL C N   1 
ATOM   8979 C  CA  . VAL D 2 293 ? -52.211 23.921  13.577  1    57.89  ? 289 VAL C CA  1 
ATOM   8980 C  C   . VAL D 2 293 ? -51.042 24.143  12.614  1    59.73  ? 289 VAL C C   1 
ATOM   8981 O  O   . VAL D 2 293 ? -51.11  23.758  11.448  1    62.27  ? 289 VAL C O   1 
ATOM   8982 C  CB  . VAL D 2 293 ? -52.093 22.581  14.334  1    54.28  ? 289 VAL C CB  1 
ATOM   8983 C  CG1 . VAL D 2 293 ? -52.02  21.401  13.366  1    54.58  ? 289 VAL C CG1 1 
ATOM   8984 C  CG2 . VAL D 2 293 ? -50.899 22.549  15.283  1    46.2   ? 289 VAL C CG2 1 
ATOM   8985 N  N   . THR D 2 294 ? -49.981 24.794  13.107  1    58     ? 290 THR C N   1 
ATOM   8986 C  CA  . THR D 2 294 ? -48.727 24.915  12.373  1    60.22  ? 290 THR C CA  1 
ATOM   8987 C  C   . THR D 2 294 ? -47.601 24.615  13.356  1    56.54  ? 290 THR C C   1 
ATOM   8988 O  O   . THR D 2 294 ? -47.887 24.319  14.497  1    58.32  ? 290 THR C O   1 
ATOM   8989 C  CB  . THR D 2 294 ? -48.58  26.302  11.74   1    64.37  ? 290 THR C CB  1 
ATOM   8990 O  OG1 . THR D 2 294 ? -48.555 27.216  12.834  1    64.35  ? 290 THR C OG1 1 
ATOM   8991 C  CG2 . THR D 2 294 ? -49.71  26.664  10.791  1    64.66  ? 290 THR C CG2 1 
ATOM   8992 N  N   . LYS D 2 295 ? -46.34  24.667  12.918  1    59.72  ? 291 LYS C N   1 
ATOM   8993 C  CA  . LYS D 2 295 ? -45.194 24.441  13.791  1    59.44  ? 291 LYS C CA  1 
ATOM   8994 C  C   . LYS D 2 295 ? -44.272 25.665  13.78   1    59.45  ? 291 LYS C C   1 
ATOM   8995 O  O   . LYS D 2 295 ? -43.232 25.647  13.119  1    61.82  ? 291 LYS C O   1 
ATOM   8996 C  CB  . LYS D 2 295 ? -44.437 23.176  13.363  1    59.65  ? 291 LYS C CB  1 
ATOM   8997 C  CG  . LYS D 2 295 ? -43.232 22.802  14.226  1    64.8   ? 291 LYS C CG  1 
ATOM   8998 C  CD  . LYS D 2 295 ? -42.204 21.837  13.634  1    65.69  ? 291 LYS C CD  1 
ATOM   8999 C  CE  . LYS D 2 295 ? -41.341 21.213  14.696  1    71.28  ? 291 LYS C CE  1 
ATOM   9000 N  NZ  . LYS D 2 295 ? -40.147 20.535  14.182  1    73.08  ? 291 LYS C NZ  1 
ATOM   9001 N  N   . PRO D 2 296 ? -44.594 26.754  14.522  1    57.8   ? 292 PRO C N   1 
ATOM   9002 C  CA  . PRO D 2 296 ? -43.717 27.928  14.595  1    60.61  ? 292 PRO C CA  1 
ATOM   9003 C  C   . PRO D 2 296 ? -42.514 27.683  15.5    1    60.62  ? 292 PRO C C   1 
ATOM   9004 O  O   . PRO D 2 296 ? -42.553 26.796  16.342  1    60.81  ? 292 PRO C O   1 
ATOM   9005 C  CB  . PRO D 2 296 ? -44.627 29.06   15.14   1    60.93  ? 292 PRO C CB  1 
ATOM   9006 C  CG  . PRO D 2 296 ? -45.771 28.352  15.838  1    56.29  ? 292 PRO C CG  1 
ATOM   9007 C  CD  . PRO D 2 296 ? -45.809 26.916  15.336  1    55.85  ? 292 PRO C CD  1 
ATOM   9008 N  N   . VAL D 2 297 ? -41.453 28.471  15.312  1    65     ? 293 VAL C N   1 
ATOM   9009 C  CA  . VAL D 2 297 ? -40.289 28.417  16.187  1    66.3   ? 293 VAL C CA  1 
ATOM   9010 C  C   . VAL D 2 297 ? -40.549 29.346  17.381  1    65.78  ? 293 VAL C C   1 
ATOM   9011 O  O   . VAL D 2 297 ? -41.154 30.406  17.22   1    69.3   ? 293 VAL C O   1 
ATOM   9012 C  CB  . VAL D 2 297 ? -38.972 28.761  15.439  1    62.5   ? 293 VAL C CB  1 
ATOM   9013 C  CG1 . VAL D 2 297 ? -38.8   27.986  14.133  1    55.52  ? 293 VAL C CG1 1 
ATOM   9014 C  CG2 . VAL D 2 297 ? -38.797 30.254  15.185  1    62.88  ? 293 VAL C CG2 1 
ATOM   9015 N  N   . PRO D 2 298 ? -40.117 29.005  18.618  1    62.57  ? 294 PRO C N   1 
ATOM   9016 C  CA  . PRO D 2 298 ? -40.17  29.959  19.743  1    64.34  ? 294 PRO C CA  1 
ATOM   9017 C  C   . PRO D 2 298 ? -39.166 31.112  19.63   1    70.57  ? 294 PRO C C   1 
ATOM   9018 O  O   . PRO D 2 298 ? -38.151 30.964  18.952  1    72.32  ? 294 PRO C O   1 
ATOM   9019 C  CB  . PRO D 2 298 ? -39.82  29.038  20.92   1    59.25  ? 294 PRO C CB  1 
ATOM   9020 C  CG  . PRO D 2 298 ? -38.908 27.978  20.318  1    56.34  ? 294 PRO C CG  1 
ATOM   9021 C  CD  . PRO D 2 298 ? -39.544 27.701  18.976  1    56.08  ? 294 PRO C CD  1 
ATOM   9022 N  N   . HIS D 2 299 ? -39.415 32.238  20.315  1    80.33  ? 295 HIS C N   1 
ATOM   9023 C  CA  . HIS D 2 299 ? -38.384 33.262  20.472  1    98.18  ? 295 HIS C CA  1 
ATOM   9024 C  C   . HIS D 2 299 ? -37.47  32.936  21.668  1    101.12 ? 295 HIS C C   1 
ATOM   9025 O  O   . HIS D 2 299 ? -37.945 32.874  22.801  1    98.76  ? 295 HIS C O   1 
ATOM   9026 C  CB  . HIS D 2 299 ? -38.999 34.672  20.498  1    104.22 ? 295 HIS C CB  1 
ATOM   9027 C  CG  . HIS D 2 299 ? -37.97  35.767  20.541  1    127.46 ? 295 HIS C CG  1 
ATOM   9028 N  ND1 . HIS D 2 299 ? -37.232 36.039  21.678  1    132.76 ? 295 HIS C ND1 1 
ATOM   9029 C  CD2 . HIS D 2 299 ? -37.514 36.621  19.598  1    130.2  ? 295 HIS C CD2 1 
ATOM   9030 C  CE1 . HIS D 2 299 ? -36.382 37.03   21.434  1    135.85 ? 295 HIS C CE1 1 
ATOM   9031 N  NE2 . HIS D 2 299 ? -36.538 37.399  20.176  1    135.3  ? 295 HIS C NE2 1 
ATOM   9032 N  N   . LEU D 2 300 ? -36.155 32.755  21.418  1    98.77  ? 296 LEU C N   1 
ATOM   9033 C  CA  . LEU D 2 300 ? -35.211 32.272  22.423  1    94.12  ? 296 LEU C CA  1 
ATOM   9034 C  C   . LEU D 2 300 ? -33.984 33.201  22.522  1    94.35  ? 296 LEU C C   1 
ATOM   9035 O  O   . LEU D 2 300 ? -33.214 33.011  23.503  1    91.11  ? 296 LEU C O   1 
ATOM   9036 C  CB  . LEU D 2 300 ? -34.787 30.827  22.16   1    83.05  ? 296 LEU C CB  1 
ATOM   9037 C  CG  . LEU D 2 300 ? -35.882 29.767  22.324  1    82.41  ? 296 LEU C CG  1 
ATOM   9038 C  CD1 . LEU D 2 300 ? -35.395 28.388  21.9    1    81.01  ? 296 LEU C CD1 1 
ATOM   9039 C  CD2 . LEU D 2 300 ? -36.387 29.698  23.75   1    78.53  ? 296 LEU C CD2 1 
HETATM 9040 N  N1  A 7ZX E 3 .   ? -10.847 -22.624 24.27   0.24 39.59  ? 601 7ZX A N1  1 
HETATM 9041 N  N1  B 7ZX E 3 .   ? -5.854  -21.284 23.442  0.25 52.59  ? 601 7ZX A N1  1 
HETATM 9042 N  N1  C 7ZX E 3 .   ? -9.315  -18.435 18.375  0.5  89.63  ? 601 7ZX A N1  1 
HETATM 9043 C  C3  A 7ZX E 3 .   ? -8.811  -21.794 23.954  0.24 43.51  ? 601 7ZX A C3  1 
HETATM 9044 C  C3  B 7ZX E 3 .   ? -8.053  -21.355 23.814  0.25 57.9   ? 601 7ZX A C3  1 
HETATM 9045 C  C3  C 7ZX E 3 .   ? -10.57  -19.735 19.681  0.5  90.37  ? 601 7ZX A C3  1 
HETATM 9046 BR BR1 A 7ZX E 3 .   ? -9.231  -19.814 21.932  0.24 63.08  ? 601 7ZX A BR1 1 
HETATM 9047 BR BR1 B 7ZX E 3 .   ? -9.086  -19.654 21.717  0.25 84.22  ? 601 7ZX A BR1 1 
HETATM 9048 BR BR1 C 7ZX E 3 .   ? -9.069  -19.696 22.108  0.5  161.73 ? 601 7ZX A BR1 1 
HETATM 9049 C  C1  A 7ZX E 3 .   ? -9.694  -21.166 23.144  0.24 46.24  ? 601 7ZX A C1  1 
HETATM 9050 C  C1  B 7ZX E 3 .   ? -7.793  -20.578 22.728  0.25 61.43  ? 601 7ZX A C1  1 
HETATM 9051 C  C1  C 7ZX E 3 .   ? -9.508  -19.26  20.355  0.5  102.96 ? 601 7ZX A C1  1 
HETATM 9052 C  C2  A 7ZX E 3 .   ? -10.929 -21.679 23.341  0.24 41.25  ? 601 7ZX A C2  1 
HETATM 9053 C  C2  B 7ZX E 3 .   ? -6.457  -20.544 22.533  0.25 54.49  ? 601 7ZX A C2  1 
HETATM 9054 C  C2  C 7ZX E 3 .   ? -8.754  -18.497 19.564  0.5  90.95  ? 601 7ZX A C2  1 
HETATM 9055 O  O1  A 7ZX E 3 .   ? -9.494  -22.692 24.666  0.24 39.4   ? 601 7ZX A O1  1 
HETATM 9056 O  O1  B 7ZX E 3 .   ? -6.878  -21.818 24.256  0.25 53.16  ? 601 7ZX A O1  1 
HETATM 9057 O  O1  C 7ZX E 3 .   ? -10.487 -19.219 18.448  0.5  81.1   ? 601 7ZX A O1  1 
HETATM 9058 N  N1  A 7ZX F 3 .   ? -33.228 18.298  32.781  0.25 46.38  ? 301 7ZX C N1  1 
HETATM 9059 N  N1  B 7ZX F 3 .   ? -32.011 18.361  28.579  0.25 28.09  ? 301 7ZX C N1  1 
HETATM 9060 N  N1  C 7ZX F 3 .   ? -35.639 11.848  31.08   0.5  56.4   ? 301 7ZX C N1  1 
HETATM 9061 C  C3  A 7ZX F 3 .   ? -32.761 17.353  30.81   0.25 47.46  ? 301 7ZX C C3  1 
HETATM 9062 C  C3  B 7ZX F 3 .   ? -32.681 16.505  27.544  0.25 27.38  ? 301 7ZX C C3  1 
HETATM 9063 C  C3  C 7ZX F 3 .   ? -35.449 13.46   29.57   0.5  53.54  ? 301 7ZX C C3  1 
HETATM 9064 BR BR1 A 7ZX F 3 .   ? -33.94  14.786  31.081  0.25 85.52  ? 301 7ZX C BR1 1 
HETATM 9065 BR BR1 B 7ZX F 3 .   ? -33.171 14.69   29.643  0.25 34.53  ? 301 7ZX C BR1 1 
HETATM 9066 BR BR1 C 7ZX F 3 .   ? -32.935 14.719  30.237  0.5  86.46  ? 301 7ZX C BR1 1 
HETATM 9067 C  C1  A 7ZX F 3 .   ? -33.455 16.517  31.582  0.25 53.86  ? 301 7ZX C C1  1 
HETATM 9068 C  C1  B 7ZX F 3 .   ? -32.677 16.307  28.846  0.25 28.93  ? 301 7ZX C C1  1 
HETATM 9069 C  C1  C 7ZX F 3 .   ? -34.378 13.507  30.367  0.5  60.81  ? 301 7ZX C C1  1 
HETATM 9070 C  C2  A 7ZX F 3 .   ? -33.726 17.093  32.77   0.25 48.69  ? 301 7ZX C C2  1 
HETATM 9071 C  C2  B 7ZX F 3 .   ? -32.278 17.435  29.482  0.25 28.43  ? 301 7ZX C C2  1 
HETATM 9072 C  C2  C 7ZX F 3 .   ? -34.524 12.526  31.27   0.5  60.56  ? 301 7ZX C C2  1 
HETATM 9073 O  O1  A 7ZX F 3 .   ? -32.608 18.469  31.522  0.25 45.65  ? 301 7ZX C O1  1 
HETATM 9074 O  O1  B 7ZX F 3 .   ? -32.272 17.757  27.335  0.25 27.65  ? 301 7ZX C O1  1 
HETATM 9075 O  O1  C 7ZX F 3 .   ? -36.243 12.462  29.972  0.5  51.83  ? 301 7ZX C O1  1 
HETATM 9076 O  O   . HOH G 4 .   ? -53.619 -14.18  14.657  1    53.53  ? 501 HOH D O   1 
HETATM 9077 O  O   . HOH G 4 .   ? -38.864 -26.36  33.141  1    54.46  ? 502 HOH D O   1 
HETATM 9078 O  O   . HOH G 4 .   ? -50.121 -4.855  28.976  1    42.77  ? 503 HOH D O   1 
HETATM 9079 O  O   . HOH G 4 .   ? -38.868 -3.264  28.165  1    43.89  ? 504 HOH D O   1 
HETATM 9080 O  O   . HOH G 4 .   ? -48.205 -7.603  45.498  1    41.83  ? 505 HOH D O   1 
HETATM 9081 O  O   . HOH G 4 .   ? -29.076 -23.254 44.731  1    37.38  ? 506 HOH D O   1 
HETATM 9082 O  O   . HOH G 4 .   ? -46.313 -4.13   46.035  1    54.41  ? 507 HOH D O   1 
HETATM 9083 O  O   . HOH G 4 .   ? -28.975 -23.150 42.029  1    29.62  ? 508 HOH D O   1 
HETATM 9084 O  O   . HOH G 4 .   ? -45.747 -6.044  33.376  1    30.38  ? 509 HOH D O   1 
HETATM 9085 O  O   . HOH G 4 .   ? -30.255 -18.859 56.304  1    58.6   ? 510 HOH D O   1 
HETATM 9086 O  O   . HOH G 4 .   ? -40.995 -1.202  42.379  1    46.66  ? 511 HOH D O   1 
HETATM 9087 O  O   . HOH G 4 .   ? -43.514 -20.13  26.929  1    52     ? 512 HOH D O   1 
HETATM 9088 O  O   . HOH G 4 .   ? -49.042 -15.85  17.099  1    42.51  ? 513 HOH D O   1 
HETATM 9089 O  O   . HOH G 4 .   ? -60.692 -15.187 50.109  1    46.75  ? 514 HOH D O   1 
HETATM 9090 O  O   . HOH G 4 .   ? -53.027 -29.342 51.239  1    52.25  ? 515 HOH D O   1 
HETATM 9091 O  O   . HOH G 4 .   ? -26.096 -30.942 36.91   1    54.26  ? 516 HOH D O   1 
HETATM 9092 O  O   . HOH G 4 .   ? -22.342 -7.592  37.469  1    50.23  ? 517 HOH D O   1 
HETATM 9093 O  O   . HOH G 4 .   ? -33.884 -10.871 25.492  1    49.52  ? 518 HOH D O   1 
HETATM 9094 O  O   . HOH G 4 .   ? -52.754 -6.123  29.03   1    47.62  ? 519 HOH D O   1 
HETATM 9095 O  O   . HOH G 4 .   ? -60.386 5.694   36.361  1    54.37  ? 520 HOH D O   1 
HETATM 9096 O  O   . HOH G 4 .   ? -44.578 -5.874  30.879  1    44.75  ? 521 HOH D O   1 
HETATM 9097 O  O   . HOH G 4 .   ? -28.025 -30.807 30.503  1    52.22  ? 522 HOH D O   1 
HETATM 9098 O  O   . HOH G 4 .   ? -35.352 -32.908 33.015  1    41.58  ? 523 HOH D O   1 
HETATM 9099 O  O   . HOH G 4 .   ? -50.789 -10.844 46.516  1    52.9   ? 524 HOH D O   1 
HETATM 9100 O  O   . HOH G 4 .   ? -43.945 -32.084 30.801  1    53.93  ? 525 HOH D O   1 
HETATM 9101 O  O   . HOH G 4 .   ? -42.137 -23.268 29.999  1    56.85  ? 526 HOH D O   1 
HETATM 9102 O  O   . HOH G 4 .   ? -51.079 -9.925  38.759  1    45.09  ? 527 HOH D O   1 
HETATM 9103 O  O   . HOH G 4 .   ? -38.392 -26.68  24.525  1    61.04  ? 528 HOH D O   1 
HETATM 9104 O  O   . HOH G 4 .   ? -58.886 5.423   26.528  1    41.32  ? 529 HOH D O   1 
HETATM 9105 O  O   . HOH G 4 .   ? -19.748 -12.448 42.582  1    43.67  ? 530 HOH D O   1 
HETATM 9106 O  O   . HOH H 4 .   ? 4.994   -19.902 -4.574  1    51.24  ? 701 HOH A O   1 
HETATM 9107 O  O   . HOH H 4 .   ? 0.868   4.818   10.731  1    52.65  ? 702 HOH A O   1 
HETATM 9108 O  O   . HOH H 4 .   ? -2.292  -44.980 21.935  1    46.49  ? 703 HOH A O   1 
HETATM 9109 O  O   . HOH H 4 .   ? -1.976  -24.167 9.158   1    46.71  ? 704 HOH A O   1 
HETATM 9110 O  O   . HOH H 4 .   ? -24.414 -18.589 12.056  1    57.69  ? 705 HOH A O   1 
HETATM 9111 O  O   . HOH H 4 .   ? -21.984 -17.866 31.546  1    36.28  ? 706 HOH A O   1 
HETATM 9112 O  O   . HOH H 4 .   ? -14.206 -46.281 -0.178  1    41.94  ? 707 HOH A O   1 
HETATM 9113 O  O   . HOH H 4 .   ? -13.016 -28.336 -5.019  1    33.09  ? 708 HOH A O   1 
HETATM 9114 O  O   . HOH H 4 .   ? -7.847  -23.829 -4.108  1    29.03  ? 709 HOH A O   1 
HETATM 9115 O  O   . HOH H 4 .   ? -15.561 -38.048 19.921  1    49.98  ? 710 HOH A O   1 
HETATM 9116 O  O   . HOH H 4 .   ? -20.028 -15.096 42.649  1    51.32  ? 711 HOH A O   1 
HETATM 9117 O  O   . HOH H 4 .   ? 9.119   -30.839 -14.819 1    53.95  ? 712 HOH A O   1 
HETATM 9118 O  O   . HOH H 4 .   ? 3.883   -20.93  -0.823  1    44.54  ? 713 HOH A O   1 
HETATM 9119 O  O   . HOH H 4 .   ? -15.231 -27.336 1.221   1    35.33  ? 714 HOH A O   1 
HETATM 9120 O  O   . HOH H 4 .   ? -7.748  -16.709 -3.877  1    34.39  ? 715 HOH A O   1 
HETATM 9121 O  O   . HOH H 4 .   ? -19.101 -24.495 19.533  1    32.29  ? 716 HOH A O   1 
HETATM 9122 O  O   . HOH H 4 .   ? -6.932  -12.941 8.369   1    45.79  ? 717 HOH A O   1 
HETATM 9123 O  O   . HOH H 4 .   ? -19.674 -10.346 32.962  1    70.81  ? 718 HOH A O   1 
HETATM 9124 O  O   . HOH H 4 .   ? 1.943   -32.234 6.182   1    38.3   ? 719 HOH A O   1 
HETATM 9125 O  O   . HOH H 4 .   ? -4.441  -8.564  5.402   1    46.08  ? 720 HOH A O   1 
HETATM 9126 O  O   . HOH H 4 .   ? -17.256 -22.332 27.809  1    42.6   ? 721 HOH A O   1 
HETATM 9127 O  O   . HOH H 4 .   ? -1.07   -24.985 -19.045 1    45.13  ? 722 HOH A O   1 
HETATM 9128 O  O   . HOH H 4 .   ? -9.409  -52.004 3.184   1    51.58  ? 723 HOH A O   1 
HETATM 9129 O  O   . HOH H 4 .   ? -14.336 -36.274 -4.929  1    48.74  ? 724 HOH A O   1 
HETATM 9130 O  O   . HOH H 4 .   ? -2.949  -20.171 -5.646  1    29.03  ? 725 HOH A O   1 
HETATM 9131 O  O   . HOH H 4 .   ? 3.347   -40.217 7.244   1    40.55  ? 726 HOH A O   1 
HETATM 9132 O  O   . HOH H 4 .   ? 15.151  -26.533 2.019   1    56.5   ? 727 HOH A O   1 
HETATM 9133 O  O   . HOH H 4 .   ? -3.547  -25.505 2.418   1    32.88  ? 728 HOH A O   1 
HETATM 9134 O  O   . HOH H 4 .   ? 1.195   -38.647 8.102   1    43.43  ? 729 HOH A O   1 
HETATM 9135 O  O   . HOH H 4 .   ? 2.365   -15.627 -8.29   1    51     ? 730 HOH A O   1 
HETATM 9136 O  O   . HOH H 4 .   ? -19.574 -21.515 17.313  1    45.34  ? 731 HOH A O   1 
HETATM 9137 O  O   . HOH H 4 .   ? 13.743  -32.190 -2.188  1    45.93  ? 732 HOH A O   1 
HETATM 9138 O  O   . HOH H 4 .   ? -7.926  -10.726 -8.023  1    41.22  ? 733 HOH A O   1 
HETATM 9139 O  O   . HOH H 4 .   ? -14.357 -27.14  -1.436  1    32.58  ? 734 HOH A O   1 
HETATM 9140 O  O   . HOH H 4 .   ? 0.155   -33.568 8.267   1    34.81  ? 735 HOH A O   1 
HETATM 9141 O  O   . HOH H 4 .   ? -18.368 -18.187 17.301  1    40.76  ? 736 HOH A O   1 
HETATM 9142 O  O   . HOH H 4 .   ? -12.167 -12.83  -9.056  1    38.58  ? 737 HOH A O   1 
HETATM 9143 O  O   . HOH H 4 .   ? -12.305 -10.889 5.453   1    38.08  ? 738 HOH A O   1 
HETATM 9144 O  O   . HOH H 4 .   ? -12.444 -28.857 -2.414  1    35.06  ? 739 HOH A O   1 
HETATM 9145 O  O   . HOH H 4 .   ? -13.147 -20.526 17.46   1    50.49  ? 740 HOH A O   1 
HETATM 9146 O  O   . HOH H 4 .   ? 11.85   -22.605 -1.398  1    40.66  ? 741 HOH A O   1 
HETATM 9147 O  O   . HOH H 4 .   ? -6.111  -25.293 -11.354 1    49.57  ? 742 HOH A O   1 
HETATM 9148 O  O   . HOH H 4 .   ? -4.382  -19.317 -10.463 1    35.6   ? 743 HOH A O   1 
HETATM 9149 O  O   . HOH H 4 .   ? -7.659  -18.371 10.641  1    30.62  ? 744 HOH A O   1 
HETATM 9150 O  O   . HOH H 4 .   ? -9.063  -12.462 37.893  1    47.26  ? 745 HOH A O   1 
HETATM 9151 O  O   . HOH H 4 .   ? -3.324  -4.562  11.173  1    52.19  ? 746 HOH A O   1 
HETATM 9152 O  O   . HOH H 4 .   ? -5.234  -15.788 -4.285  1    39.66  ? 747 HOH A O   1 
HETATM 9153 O  O   . HOH H 4 .   ? -9.74   -46.952 -2.213  1    43.06  ? 748 HOH A O   1 
HETATM 9154 O  O   . HOH H 4 .   ? -2.851  -48.306 -3.42   1    59.13  ? 749 HOH A O   1 
HETATM 9155 O  O   . HOH H 4 .   ? 0.251   -37.301 -10.146 1    44.14  ? 750 HOH A O   1 
HETATM 9156 O  O   . HOH H 4 .   ? -16.988 -32.736 -3.871  1    41.08  ? 751 HOH A O   1 
HETATM 9157 O  O   . HOH H 4 .   ? -2.41   -15.697 -3.549  1    39.14  ? 752 HOH A O   1 
HETATM 9158 O  O   . HOH H 4 .   ? -25.485 -17.578 19.508  1    60.45  ? 753 HOH A O   1 
HETATM 9159 O  O   . HOH H 4 .   ? 7.938   -35.833 3.053   1    49.06  ? 754 HOH A O   1 
HETATM 9160 O  O   . HOH H 4 .   ? -6.098  -6.532  -1.923  1    41.42  ? 755 HOH A O   1 
HETATM 9161 O  O   . HOH H 4 .   ? -23.396 -29.505 10.636  1    34.93  ? 756 HOH A O   1 
HETATM 9162 O  O   . HOH H 4 .   ? 13.291  -27.271 -10.159 1    62.49  ? 757 HOH A O   1 
HETATM 9163 O  O   . HOH H 4 .   ? -15.957 -42.156 -2.769  1    42.18  ? 758 HOH A O   1 
HETATM 9164 O  O   . HOH H 4 .   ? -3.813  -51.663 9.246   1    48.16  ? 759 HOH A O   1 
HETATM 9165 O  O   . HOH H 4 .   ? -18.277 -24.216 31.708  1    39.74  ? 760 HOH A O   1 
HETATM 9166 O  O   . HOH H 4 .   ? -12.927 -50.114 4.308   1    43.37  ? 761 HOH A O   1 
HETATM 9167 O  O   . HOH H 4 .   ? -16.867 -27.229 25.431  1    45.29  ? 762 HOH A O   1 
HETATM 9168 O  O   . HOH H 4 .   ? 8.778   -41.061 -5.769  1    48.85  ? 763 HOH A O   1 
HETATM 9169 O  O   . HOH H 4 .   ? 4.663   -21.91  8.329   1    47.78  ? 764 HOH A O   1 
HETATM 9170 O  O   . HOH H 4 .   ? -24.247 -5.229  24.374  1    54.81  ? 765 HOH A O   1 
HETATM 9171 O  O   . HOH H 4 .   ? -4.632  -36.012 -8.281  1    34     ? 766 HOH A O   1 
HETATM 9172 O  O   . HOH H 4 .   ? -1.153  -18.017 -3.61   1    51.12  ? 767 HOH A O   1 
HETATM 9173 O  O   . HOH H 4 .   ? 11.369  -20.886 1.532   1    53.17  ? 768 HOH A O   1 
HETATM 9174 O  O   . HOH H 4 .   ? -2.817  4.564   19.823  1    58.39  ? 769 HOH A O   1 
HETATM 9175 O  O   . HOH H 4 .   ? 3.115   -13.033 -0.291  1    54.01  ? 770 HOH A O   1 
HETATM 9176 O  O   . HOH H 4 .   ? -17.455 -4.071  26.05   1    51.5   ? 771 HOH A O   1 
HETATM 9177 O  O   . HOH H 4 .   ? 5.144   -26.128 9.346   1    54.87  ? 772 HOH A O   1 
HETATM 9178 O  O   . HOH H 4 .   ? 13.301  -36.447 2.715   1    57.4   ? 773 HOH A O   1 
HETATM 9179 O  O   . HOH H 4 .   ? -17.076 -35.682 -5.031  1    41.02  ? 774 HOH A O   1 
HETATM 9180 O  O   . HOH I 4 .   ? -26.478 10.839  -11.882 1    47.57  ? 501 HOH B O   1 
HETATM 9181 O  O   . HOH I 4 .   ? -3.109  15.941  11.27   1    53.95  ? 502 HOH B O   1 
HETATM 9182 O  O   . HOH I 4 .   ? -17.786 -10.708 -5.001  1    50.22  ? 503 HOH B O   1 
HETATM 9183 O  O   . HOH I 4 .   ? -32.211 -10.145 0.78    1    33.25  ? 504 HOH B O   1 
HETATM 9184 O  O   . HOH I 4 .   ? -28.252 -21.768 -23.047 1    48.16  ? 505 HOH B O   1 
HETATM 9185 O  O   . HOH I 4 .   ? -12.544 -10.187 2.926   1    43.22  ? 506 HOH B O   1 
HETATM 9186 O  O   . HOH I 4 .   ? -5.656  -6.235  6.033   1    44.85  ? 507 HOH B O   1 
HETATM 9187 O  O   . HOH I 4 .   ? -19.562 -12.93  -0.817  1    38.73  ? 508 HOH B O   1 
HETATM 9188 O  O   . HOH I 4 .   ? -25.917 11.14   -0.416  1    40.53  ? 509 HOH B O   1 
HETATM 9189 O  O   . HOH I 4 .   ? -12.189 4.019   -5.836  1    37.12  ? 510 HOH B O   1 
HETATM 9190 O  O   . HOH I 4 .   ? -21.659 11.409  -11.891 1    51.74  ? 511 HOH B O   1 
HETATM 9191 O  O   . HOH I 4 .   ? -27.115 10.4    17.933  1    43.26  ? 512 HOH B O   1 
HETATM 9192 O  O   . HOH I 4 .   ? -29.212 11.565  13.855  1    51.66  ? 513 HOH B O   1 
HETATM 9193 O  O   . HOH I 4 .   ? -12.095 -22.55  -10.405 1    43.79  ? 514 HOH B O   1 
HETATM 9194 O  O   . HOH I 4 .   ? -16.159 -8.221  1.769   1    33.7   ? 515 HOH B O   1 
HETATM 9195 O  O   . HOH I 4 .   ? -5.996  -3.49   -3.82   1    35.31  ? 516 HOH B O   1 
HETATM 9196 O  O   . HOH I 4 .   ? -5.971  14.482  19.111  1    48.17  ? 517 HOH B O   1 
HETATM 9197 O  O   . HOH I 4 .   ? -19.472 -10.914 3.199   1    51.16  ? 518 HOH B O   1 
HETATM 9198 O  O   . HOH I 4 .   ? -30.311 -11.855 -4.916  1    40.8   ? 519 HOH B O   1 
HETATM 9199 O  O   . HOH I 4 .   ? -3.992  -4.459  -1.048  1    52.49  ? 520 HOH B O   1 
HETATM 9200 O  O   . HOH I 4 .   ? -16.428 14.971  -8.067  1    48.86  ? 521 HOH B O   1 
HETATM 9201 O  O   . HOH I 4 .   ? -18.151 -8.579  3.611   1    32.91  ? 522 HOH B O   1 
HETATM 9202 O  O   . HOH I 4 .   ? -1.584  13.21   13.706  1    51.21  ? 523 HOH B O   1 
HETATM 9203 O  O   . HOH I 4 .   ? -24.317 -3.884  13.915  1    49.92  ? 524 HOH B O   1 
HETATM 9204 O  O   . HOH I 4 .   ? -35.461 2.098   7.702   1    56.28  ? 525 HOH B O   1 
HETATM 9205 O  O   . HOH I 4 .   ? -19.2   10.161  -11.241 1    41.7   ? 526 HOH B O   1 
HETATM 9206 O  O   . HOH I 4 .   ? -28.23  8.725   -24.236 1    46.86  ? 527 HOH B O   1 
HETATM 9207 O  O   . HOH I 4 .   ? -19.502 -9.18   10.554  1    51.73  ? 528 HOH B O   1 
HETATM 9208 O  O   . HOH I 4 .   ? -32.986 8.244   1.477   1    52.32  ? 529 HOH B O   1 
HETATM 9209 O  O   . HOH I 4 .   ? -19.002 10.214  -8.389  1    56.38  ? 530 HOH B O   1 
HETATM 9210 O  O   . HOH I 4 .   ? -37.356 -6.838  -6.091  1    57.3   ? 531 HOH B O   1 
HETATM 9211 O  O   . HOH I 4 .   ? -22.716 -1.923  -1.875  1    39.53  ? 532 HOH B O   1 
HETATM 9212 O  O   . HOH I 4 .   ? -28.403 15.236  17.512  1    54.84  ? 533 HOH B O   1 
HETATM 9213 O  O   . HOH I 4 .   ? -12.723 -0.388  -25.514 1    49.71  ? 534 HOH B O   1 
HETATM 9214 O  O   . HOH I 4 .   ? -15.84  16.603  7.807   1    51.77  ? 535 HOH B O   1 
HETATM 9215 O  O   . HOH I 4 .   ? -17.831 -10.21  -25.001 1    51.45  ? 536 HOH B O   1 
HETATM 9216 O  O   . HOH I 4 .   ? -27.711 -3.86   3.092   1    39.59  ? 537 HOH B O   1 
HETATM 9217 O  O   . HOH I 4 .   ? -31.639 10.032  2.426   1    53.69  ? 538 HOH B O   1 
HETATM 9218 O  O   . HOH I 4 .   ? -13.938 -21.505 -11.999 1    42.45  ? 539 HOH B O   1 
HETATM 9219 O  O   . HOH I 4 .   ? -21.023 8.22    -17.812 1    37.13  ? 540 HOH B O   1 
HETATM 9220 O  O   . HOH I 4 .   ? -18.028 -1.202  -7.79   1    56.29  ? 541 HOH B O   1 
HETATM 9221 O  O   . HOH I 4 .   ? -30.594 16.048  2.833   1    45.8   ? 542 HOH B O   1 
HETATM 9222 O  O   . HOH I 4 .   ? -24.799 -24.319 -1.418  1    35.16  ? 543 HOH B O   1 
HETATM 9223 O  O   . HOH I 4 .   ? -39.125 3.316   -4.98   1    51.53  ? 544 HOH B O   1 
HETATM 9224 O  O   . HOH I 4 .   ? -38.012 -10.889 -15.531 1    36.7   ? 545 HOH B O   1 
HETATM 9225 O  O   . HOH I 4 .   ? -28.152 -18.005 -18.002 1    56.92  ? 546 HOH B O   1 
HETATM 9226 O  O   . HOH I 4 .   ? -22.193 3.592   -26.551 1    44.38  ? 547 HOH B O   1 
HETATM 9227 O  O   . HOH I 4 .   ? -29.818 9.136   12.66   1    56.07  ? 548 HOH B O   1 
HETATM 9228 O  O   . HOH I 4 .   ? -36.935 -2.309  -7.366  1    41.55  ? 549 HOH B O   1 
HETATM 9229 O  O   . HOH I 4 .   ? -20.572 -3.161  20.864  1    51.84  ? 550 HOH B O   1 
HETATM 9230 O  O   . HOH I 4 .   ? -24.362 -24.274 -4.148  1    46.33  ? 551 HOH B O   1 
HETATM 9231 O  O   . HOH I 4 .   ? -22.915 20.395  0.798   1    50.94  ? 552 HOH B O   1 
HETATM 9232 O  O   . HOH I 4 .   ? -24.404 -17.544 -9.11   1    47.32  ? 553 HOH B O   1 
HETATM 9233 O  O   . HOH I 4 .   ? -23.568 -24.972 -8.669  1    50.86  ? 554 HOH B O   1 
HETATM 9234 O  O   . HOH I 4 .   ? -26.122 8.442   19.66   1    60.42  ? 555 HOH B O   1 
HETATM 9235 O  O   . HOH I 4 .   ? -27.764 -8.724  -29.669 1    54.2   ? 556 HOH B O   1 
HETATM 9236 O  O   . HOH I 4 .   ? -26.931 4.614   -1.238  1    53.6   ? 557 HOH B O   1 
HETATM 9237 O  O   . HOH I 4 .   ? -30.991 -17.863 -18.365 1    42.94  ? 558 HOH B O   1 
HETATM 9238 O  O   . HOH I 4 .   ? -29.172 -12.718 -20.664 1    50.42  ? 559 HOH B O   1 
HETATM 9239 O  O   . HOH I 4 .   ? -18.864 -6.951  19.762  1    47.56  ? 560 HOH B O   1 
HETATM 9240 O  O   . HOH I 4 .   ? -13.916 18.265  7.061   1    46.15  ? 561 HOH B O   1 
HETATM 9241 O  O   . HOH I 4 .   ? -25.566 -2.104  12.171  1    46.3   ? 562 HOH B O   1 
HETATM 9242 O  O   . HOH I 4 .   ? -22.194 10.695  -8.336  1    55.2   ? 563 HOH B O   1 
HETATM 9243 O  O   . HOH I 4 .   ? -28.499 15.56   -12.841 1    60.01  ? 564 HOH B O   1 
HETATM 9244 O  O   . HOH I 4 .   ? -24.595 -28.224 -4.485  1    46.36  ? 565 HOH B O   1 
HETATM 9245 O  O   . HOH I 4 .   ? -24.069 10.112  -11.166 1    50.33  ? 566 HOH B O   1 
HETATM 9246 O  O   . HOH I 4 .   ? -27.895 -1.251  2.284   1    42.27  ? 567 HOH B O   1 
HETATM 9247 O  O   . HOH J 4 .   ? -61.509 9.008   29.466  1    44.22  ? 401 HOH C O   1 
HETATM 9248 O  O   . HOH J 4 .   ? -31.162 13.446  43.385  1    63.12  ? 402 HOH C O   1 
HETATM 9249 O  O   . HOH J 4 .   ? -58.811 28.239  17.341  1    56.77  ? 403 HOH C O   1 
HETATM 9250 O  O   . HOH J 4 .   ? -18.975 4.443   26.046  1    44.19  ? 404 HOH C O   1 
HETATM 9251 O  O   . HOH J 4 .   ? -43.938 24.769  17.153  1    39.49  ? 405 HOH C O   1 
HETATM 9252 O  O   . HOH J 4 .   ? -45.803 -2.269  35.421  1    35.87  ? 406 HOH C O   1 
HETATM 9253 O  O   . HOH J 4 .   ? -54.637 2.482   41.462  1    52.57  ? 407 HOH C O   1 
HETATM 9254 O  O   . HOH J 4 .   ? -37.455 12.276  20.062  1    46.1   ? 408 HOH C O   1 
HETATM 9255 O  O   . HOH J 4 .   ? -59.573 -1.848  36.523  1    50.57  ? 409 HOH C O   1 
HETATM 9256 O  O   . HOH J 4 .   ? -54.638 2.135   38.649  1    47.61  ? 410 HOH C O   1 
HETATM 9257 O  O   . HOH J 4 .   ? -64.572 13.94   24.458  1    60.18  ? 411 HOH C O   1 
HETATM 9258 O  O   . HOH J 4 .   ? -39.799 24.409  20.725  1    55.33  ? 412 HOH C O   1 
HETATM 9259 O  O   . HOH J 4 .   ? -40.662 35.038  35.088  1    49.6   ? 413 HOH C O   1 
HETATM 9260 O  O   . HOH J 4 .   ? -35.287 0.793   43.859  1    39.22  ? 414 HOH C O   1 
HETATM 9261 O  O   . HOH J 4 .   ? -51.356 24.44   35.706  1    43.74  ? 415 HOH C O   1 
HETATM 9262 O  O   . HOH J 4 .   ? -57.449 8.408   27.532  1    40.75  ? 416 HOH C O   1 
HETATM 9263 O  O   . HOH J 4 .   ? -55.001 19.217  39.572  1    32.4   ? 417 HOH C O   1 
HETATM 9264 O  O   . HOH J 4 .   ? -48.831 9.449   18.316  1    51.5   ? 418 HOH C O   1 
HETATM 9265 O  O   . HOH J 4 .   ? -52.396 23.386  38.157  1    47.78  ? 419 HOH C O   1 
HETATM 9266 O  O   . HOH J 4 .   ? -55.11  17.662  52.619  1    44.78  ? 420 HOH C O   1 
HETATM 9267 O  O   . HOH J 4 .   ? -55.155 9.394   26.312  1    36.81  ? 421 HOH C O   1 
HETATM 9268 O  O   . HOH J 4 .   ? -49.604 13.072  34.317  1    39.21  ? 422 HOH C O   1 
HETATM 9269 O  O   . HOH J 4 .   ? -57.613 3.993   16.951  1    50.45  ? 423 HOH C O   1 
HETATM 9270 O  O   . HOH J 4 .   ? -58.13  7.712   35.597  1    40.49  ? 424 HOH C O   1 
HETATM 9271 O  O   . HOH J 4 .   ? -25.663 17.929  18.858  1    50.08  ? 425 HOH C O   1 
HETATM 9272 O  O   . HOH J 4 .   ? -34.823 13.857  33.606  1    63.8   ? 426 HOH C O   1 
HETATM 9273 O  O   . HOH J 4 .   ? -37.491 29.464  35.143  1    54.83  ? 427 HOH C O   1 
HETATM 9274 O  O   . HOH J 4 .   ? -42.512 9.693   34.587  1    34.4   ? 428 HOH C O   1 
HETATM 9275 O  O   . HOH J 4 .   ? -37.745 19.953  15.572  1    47.15  ? 429 HOH C O   1 
HETATM 9276 O  O   . HOH J 4 .   ? -62.477 3.529   43.774  1    39.76  ? 430 HOH C O   1 
HETATM 9277 O  O   . HOH J 4 .   ? -32.31  22.755  21.732  1    51.65  ? 431 HOH C O   1 
HETATM 9278 O  O   . HOH J 4 .   ? -48.142 -3.944  43.192  1    41.38  ? 432 HOH C O   1 
HETATM 9279 O  O   . HOH J 4 .   ? -13.955 5.625   21.35   1    42.53  ? 433 HOH C O   1 
HETATM 9280 O  O   . HOH J 4 .   ? -58.998 10.226  29.081  1    42.88  ? 434 HOH C O   1 
HETATM 9281 O  O   . HOH J 4 .   ? -62.601 -4.352  41.548  1    52.53  ? 435 HOH C O   1 
HETATM 9282 O  O   . HOH J 4 .   ? -43.751 -0.74   34.83   1    43.12  ? 436 HOH C O   1 
HETATM 9283 O  O   . HOH J 4 .   ? -23.119 1.066   24.63   1    60.16  ? 437 HOH C O   1 
HETATM 9284 O  O   . HOH J 4 .   ? -36.255 7.249   23.512  1    45.84  ? 438 HOH C O   1 
HETATM 9285 O  O   . HOH J 4 .   ? -54.009 23.78   53.277  1    51.55  ? 439 HOH C O   1 
HETATM 9286 O  O   . HOH J 4 .   ? -21.834 -0.269  28.782  1    40.12  ? 440 HOH C O   1 
HETATM 9287 O  O   . HOH J 4 .   ? -57.429 27.374  41.514  1    54.42  ? 441 HOH C O   1 
HETATM 9288 O  O   . HOH J 4 .   ? -35.665 16.786  17.715  1    52.64  ? 442 HOH C O   1 
HETATM 9289 O  O   . HOH J 4 .   ? -13.863 18.112  18.877  1    54.46  ? 443 HOH C O   1 
HETATM 9290 O  O   . HOH J 4 .   ? -42.067 33.074  21.611  1    57.86  ? 444 HOH C O   1 
HETATM 9291 O  O   . HOH J 4 .   ? -38.94  9.62    16.334  1    47.91  ? 445 HOH C O   1 
HETATM 9292 O  O   . HOH J 4 .   ? -61.655 3.485   41.068  1    44.37  ? 446 HOH C O   1 
HETATM 9293 O  O   . HOH J 4 .   ? -50.419 6.856   18.992  1    45.51  ? 447 HOH C O   1 
HETATM 9294 O  O   . HOH J 4 .   ? -43.944 31.561  18.32   1    62.33  ? 448 HOH C O   1 
HETATM 9295 O  O   . HOH J 4 .   ? -46.707 36.855  22.07   1    60.8   ? 449 HOH C O   1 
HETATM 9296 O  O   . HOH J 4 .   ? -30.272 23.326  29.642  1    48.98  ? 450 HOH C O   1 
HETATM 9297 O  O   . HOH J 4 .   ? -24.129 9.119   22.072  1    59.72  ? 451 HOH C O   1 
HETATM 9298 O  O   . HOH J 4 .   ? -57.710 25.677  53.141  1    60.05  ? 452 HOH C O   1 
HETATM 9299 O  O   . HOH J 4 .   ? -51.794 19.096  10.942  1    60.23  ? 453 HOH C O   1 
# 
