data_9ET9
# 
_entry.id   9ET9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ET9         pdb_00009et9 10.2210/pdb9et9/pdb 
WWPDB D_1292136997 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ET9 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Cyclin-A2                   30817.473 2   ?         ? ? ? 
2 polymer     man 'Cyclin-dependent kinase 2' 34354.770 2   2.7.11.22 ? ? ? 
3 non-polymer syn 4-bromanylpyridin-2-amine   173.011   10  ?         ? ? ? 
4 water       nat water                       18.015    247 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 Cyclin-A                                            
2 'Cell division protein kinase 2,p33 protein kinase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
D,B ? 
2 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 4-bromanylpyridin-2-amine HEW 
4 water                     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   VAL n 
1 3   ASN n 
1 4   GLU n 
1 5   VAL n 
1 6   PRO n 
1 7   ASP n 
1 8   TYR n 
1 9   HIS n 
1 10  GLU n 
1 11  ASP n 
1 12  ILE n 
1 13  HIS n 
1 14  THR n 
1 15  TYR n 
1 16  LEU n 
1 17  ARG n 
1 18  GLU n 
1 19  MET n 
1 20  GLU n 
1 21  VAL n 
1 22  LYS n 
1 23  CYS n 
1 24  LYS n 
1 25  PRO n 
1 26  LYS n 
1 27  VAL n 
1 28  GLY n 
1 29  TYR n 
1 30  MET n 
1 31  LYS n 
1 32  LYS n 
1 33  GLN n 
1 34  PRO n 
1 35  ASP n 
1 36  ILE n 
1 37  THR n 
1 38  ASN n 
1 39  SER n 
1 40  MET n 
1 41  ARG n 
1 42  ALA n 
1 43  ILE n 
1 44  LEU n 
1 45  VAL n 
1 46  ASP n 
1 47  TRP n 
1 48  LEU n 
1 49  VAL n 
1 50  GLU n 
1 51  VAL n 
1 52  GLY n 
1 53  GLU n 
1 54  GLU n 
1 55  TYR n 
1 56  LYS n 
1 57  LEU n 
1 58  GLN n 
1 59  ASN n 
1 60  GLU n 
1 61  THR n 
1 62  LEU n 
1 63  HIS n 
1 64  LEU n 
1 65  ALA n 
1 66  VAL n 
1 67  ASN n 
1 68  TYR n 
1 69  ILE n 
1 70  ASP n 
1 71  ARG n 
1 72  PHE n 
1 73  LEU n 
1 74  SER n 
1 75  SER n 
1 76  MET n 
1 77  SER n 
1 78  VAL n 
1 79  LEU n 
1 80  ARG n 
1 81  GLY n 
1 82  LYS n 
1 83  LEU n 
1 84  GLN n 
1 85  LEU n 
1 86  VAL n 
1 87  GLY n 
1 88  THR n 
1 89  ALA n 
1 90  ALA n 
1 91  MET n 
1 92  LEU n 
1 93  LEU n 
1 94  ALA n 
1 95  SER n 
1 96  LYS n 
1 97  PHE n 
1 98  GLU n 
1 99  GLU n 
1 100 ILE n 
1 101 TYR n 
1 102 PRO n 
1 103 PRO n 
1 104 GLU n 
1 105 VAL n 
1 106 ALA n 
1 107 GLU n 
1 108 PHE n 
1 109 VAL n 
1 110 TYR n 
1 111 ILE n 
1 112 THR n 
1 113 ASP n 
1 114 ASP n 
1 115 THR n 
1 116 TYR n 
1 117 THR n 
1 118 LYS n 
1 119 LYS n 
1 120 GLN n 
1 121 VAL n 
1 122 LEU n 
1 123 ARG n 
1 124 MET n 
1 125 GLU n 
1 126 HIS n 
1 127 LEU n 
1 128 VAL n 
1 129 LEU n 
1 130 LYS n 
1 131 VAL n 
1 132 LEU n 
1 133 ALA n 
1 134 PHE n 
1 135 ASP n 
1 136 LEU n 
1 137 ALA n 
1 138 ALA n 
1 139 PRO n 
1 140 THR n 
1 141 ILE n 
1 142 ASN n 
1 143 GLN n 
1 144 PHE n 
1 145 LEU n 
1 146 THR n 
1 147 GLN n 
1 148 TYR n 
1 149 PHE n 
1 150 LEU n 
1 151 HIS n 
1 152 GLN n 
1 153 GLN n 
1 154 PRO n 
1 155 ALA n 
1 156 ASN n 
1 157 CYS n 
1 158 LYS n 
1 159 VAL n 
1 160 GLU n 
1 161 SER n 
1 162 LEU n 
1 163 ALA n 
1 164 MET n 
1 165 PHE n 
1 166 LEU n 
1 167 GLY n 
1 168 GLU n 
1 169 LEU n 
1 170 SER n 
1 171 LEU n 
1 172 ILE n 
1 173 ASP n 
1 174 ALA n 
1 175 ASP n 
1 176 PRO n 
1 177 TYR n 
1 178 LEU n 
1 179 LYS n 
1 180 TYR n 
1 181 LEU n 
1 182 PRO n 
1 183 SER n 
1 184 VAL n 
1 185 ILE n 
1 186 ALA n 
1 187 ALA n 
1 188 ALA n 
1 189 ALA n 
1 190 PHE n 
1 191 HIS n 
1 192 LEU n 
1 193 ALA n 
1 194 LEU n 
1 195 TYR n 
1 196 THR n 
1 197 VAL n 
1 198 THR n 
1 199 GLY n 
1 200 GLN n 
1 201 SER n 
1 202 TRP n 
1 203 PRO n 
1 204 GLU n 
1 205 SER n 
1 206 LEU n 
1 207 VAL n 
1 208 GLN n 
1 209 LYS n 
1 210 THR n 
1 211 GLY n 
1 212 TYR n 
1 213 THR n 
1 214 LEU n 
1 215 GLU n 
1 216 THR n 
1 217 LEU n 
1 218 LYS n 
1 219 PRO n 
1 220 CYS n 
1 221 LEU n 
1 222 LEU n 
1 223 ASP n 
1 224 LEU n 
1 225 HIS n 
1 226 GLN n 
1 227 THR n 
1 228 TYR n 
1 229 LEU n 
1 230 ARG n 
1 231 ALA n 
1 232 PRO n 
1 233 GLN n 
1 234 HIS n 
1 235 ALA n 
1 236 GLN n 
1 237 GLN n 
1 238 SER n 
1 239 ILE n 
1 240 ARG n 
1 241 GLU n 
1 242 LYS n 
1 243 TYR n 
1 244 LYS n 
1 245 ASN n 
1 246 SER n 
1 247 LYS n 
1 248 TYR n 
1 249 HIS n 
1 250 GLY n 
1 251 VAL n 
1 252 SER n 
1 253 LEU n 
1 254 LEU n 
1 255 ASN n 
1 256 PRO n 
1 257 PRO n 
1 258 GLU n 
1 259 THR n 
1 260 LEU n 
1 261 ASN n 
1 262 VAL n 
1 263 HIS n 
1 264 HIS n 
1 265 HIS n 
1 266 HIS n 
1 267 HIS n 
1 268 HIS n 
2 1   GLY n 
2 2   PRO n 
2 3   GLY n 
2 4   SER n 
2 5   MET n 
2 6   GLU n 
2 7   ASN n 
2 8   PHE n 
2 9   GLN n 
2 10  LYS n 
2 11  VAL n 
2 12  GLU n 
2 13  LYS n 
2 14  ILE n 
2 15  GLY n 
2 16  GLU n 
2 17  GLY n 
2 18  THR n 
2 19  TYR n 
2 20  GLY n 
2 21  VAL n 
2 22  VAL n 
2 23  TYR n 
2 24  LYS n 
2 25  ALA n 
2 26  ARG n 
2 27  ASN n 
2 28  LYS n 
2 29  LEU n 
2 30  THR n 
2 31  GLY n 
2 32  GLU n 
2 33  VAL n 
2 34  VAL n 
2 35  ALA n 
2 36  LEU n 
2 37  LYS n 
2 38  LYS n 
2 39  ILE n 
2 40  ARG n 
2 41  LEU n 
2 42  ASP n 
2 43  THR n 
2 44  GLU n 
2 45  THR n 
2 46  GLU n 
2 47  GLY n 
2 48  VAL n 
2 49  PRO n 
2 50  SER n 
2 51  THR n 
2 52  ALA n 
2 53  ILE n 
2 54  ARG n 
2 55  GLU n 
2 56  ILE n 
2 57  SER n 
2 58  LEU n 
2 59  LEU n 
2 60  LYS n 
2 61  GLU n 
2 62  LEU n 
2 63  ASN n 
2 64  HIS n 
2 65  PRO n 
2 66  ASN n 
2 67  ILE n 
2 68  VAL n 
2 69  LYS n 
2 70  LEU n 
2 71  LEU n 
2 72  ASP n 
2 73  VAL n 
2 74  ILE n 
2 75  HIS n 
2 76  THR n 
2 77  GLU n 
2 78  ASN n 
2 79  LYS n 
2 80  LEU n 
2 81  TYR n 
2 82  LEU n 
2 83  VAL n 
2 84  PHE n 
2 85  GLU n 
2 86  PHE n 
2 87  LEU n 
2 88  HIS n 
2 89  GLN n 
2 90  ASP n 
2 91  LEU n 
2 92  LYS n 
2 93  LYS n 
2 94  PHE n 
2 95  MET n 
2 96  ASP n 
2 97  ALA n 
2 98  SER n 
2 99  ALA n 
2 100 LEU n 
2 101 THR n 
2 102 GLY n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 PRO n 
2 107 LEU n 
2 108 ILE n 
2 109 LYS n 
2 110 SER n 
2 111 TYR n 
2 112 LEU n 
2 113 PHE n 
2 114 GLN n 
2 115 LEU n 
2 116 LEU n 
2 117 GLN n 
2 118 GLY n 
2 119 LEU n 
2 120 ALA n 
2 121 PHE n 
2 122 CYS n 
2 123 HIS n 
2 124 SER n 
2 125 HIS n 
2 126 ARG n 
2 127 VAL n 
2 128 LEU n 
2 129 HIS n 
2 130 ARG n 
2 131 ASP n 
2 132 LEU n 
2 133 LYS n 
2 134 PRO n 
2 135 GLN n 
2 136 ASN n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ASN n 
2 141 THR n 
2 142 GLU n 
2 143 GLY n 
2 144 ALA n 
2 145 ILE n 
2 146 LYS n 
2 147 LEU n 
2 148 ALA n 
2 149 ASP n 
2 150 PHE n 
2 151 GLY n 
2 152 LEU n 
2 153 ALA n 
2 154 ARG n 
2 155 ALA n 
2 156 PHE n 
2 157 GLY n 
2 158 VAL n 
2 159 PRO n 
2 160 VAL n 
2 161 ARG n 
2 162 THR n 
2 163 TYR n 
2 164 TPO n 
2 165 HIS n 
2 166 GLU n 
2 167 VAL n 
2 168 VAL n 
2 169 THR n 
2 170 LEU n 
2 171 TRP n 
2 172 TYR n 
2 173 ARG n 
2 174 ALA n 
2 175 PRO n 
2 176 GLU n 
2 177 ILE n 
2 178 LEU n 
2 179 LEU n 
2 180 GLY n 
2 181 CYS n 
2 182 LYS n 
2 183 TYR n 
2 184 TYR n 
2 185 SER n 
2 186 THR n 
2 187 ALA n 
2 188 VAL n 
2 189 ASP n 
2 190 ILE n 
2 191 TRP n 
2 192 SER n 
2 193 LEU n 
2 194 GLY n 
2 195 CYS n 
2 196 ILE n 
2 197 PHE n 
2 198 ALA n 
2 199 GLU n 
2 200 MET n 
2 201 VAL n 
2 202 THR n 
2 203 ARG n 
2 204 ARG n 
2 205 ALA n 
2 206 LEU n 
2 207 PHE n 
2 208 PRO n 
2 209 GLY n 
2 210 ASP n 
2 211 SER n 
2 212 GLU n 
2 213 ILE n 
2 214 ASP n 
2 215 GLN n 
2 216 LEU n 
2 217 PHE n 
2 218 ARG n 
2 219 ILE n 
2 220 PHE n 
2 221 ARG n 
2 222 THR n 
2 223 LEU n 
2 224 GLY n 
2 225 THR n 
2 226 PRO n 
2 227 ASP n 
2 228 GLU n 
2 229 VAL n 
2 230 VAL n 
2 231 TRP n 
2 232 PRO n 
2 233 GLY n 
2 234 VAL n 
2 235 THR n 
2 236 SER n 
2 237 MET n 
2 238 PRO n 
2 239 ASP n 
2 240 TYR n 
2 241 LYS n 
2 242 PRO n 
2 243 SER n 
2 244 PHE n 
2 245 PRO n 
2 246 LYS n 
2 247 TRP n 
2 248 ALA n 
2 249 ARG n 
2 250 GLN n 
2 251 ASP n 
2 252 PHE n 
2 253 SER n 
2 254 LYS n 
2 255 VAL n 
2 256 VAL n 
2 257 PRO n 
2 258 PRO n 
2 259 LEU n 
2 260 ASP n 
2 261 GLU n 
2 262 ASP n 
2 263 GLY n 
2 264 ARG n 
2 265 SER n 
2 266 LEU n 
2 267 LEU n 
2 268 SER n 
2 269 GLN n 
2 270 MET n 
2 271 LEU n 
2 272 HIS n 
2 273 TYR n 
2 274 ASP n 
2 275 PRO n 
2 276 ASN n 
2 277 LYS n 
2 278 ARG n 
2 279 ILE n 
2 280 SER n 
2 281 ALA n 
2 282 LYS n 
2 283 ALA n 
2 284 ALA n 
2 285 LEU n 
2 286 ALA n 
2 287 HIS n 
2 288 PRO n 
2 289 PHE n 
2 290 PHE n 
2 291 GLN n 
2 292 ASP n 
2 293 VAL n 
2 294 THR n 
2 295 LYS n 
2 296 PRO n 
2 297 VAL n 
2 298 PRO n 
2 299 HIS n 
2 300 LEU n 
2 301 ARG n 
2 302 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
2 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                   ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                  ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'           ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                  ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                 ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'           ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                   ?                  'C2 H5 N O2'     75.067  
HEW non-polymer         . 4-bromanylpyridin-2-amine ?                  'C5 H5 Br N2'    173.011 
HIS 'L-peptide linking' y HISTIDINE                 ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                     ?                  'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                   ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                    ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE             ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                   ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                    ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                 ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE          PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN                ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                  ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                    ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   171 171 GLY GLY D . n 
A 1 2   VAL 2   172 172 VAL VAL D . n 
A 1 3   ASN 3   173 173 ASN ASN D . n 
A 1 4   GLU 4   174 174 GLU GLU D . n 
A 1 5   VAL 5   175 175 VAL VAL D . n 
A 1 6   PRO 6   176 176 PRO PRO D . n 
A 1 7   ASP 7   177 177 ASP ASP D . n 
A 1 8   TYR 8   178 178 TYR TYR D . n 
A 1 9   HIS 9   179 179 HIS HIS D . n 
A 1 10  GLU 10  180 180 GLU GLU D . n 
A 1 11  ASP 11  181 181 ASP ASP D . n 
A 1 12  ILE 12  182 182 ILE ILE D . n 
A 1 13  HIS 13  183 183 HIS HIS D . n 
A 1 14  THR 14  184 184 THR THR D . n 
A 1 15  TYR 15  185 185 TYR TYR D . n 
A 1 16  LEU 16  186 186 LEU LEU D . n 
A 1 17  ARG 17  187 187 ARG ARG D . n 
A 1 18  GLU 18  188 188 GLU GLU D . n 
A 1 19  MET 19  189 189 MET MET D . n 
A 1 20  GLU 20  190 190 GLU GLU D . n 
A 1 21  VAL 21  191 191 VAL VAL D . n 
A 1 22  LYS 22  192 192 LYS LYS D . n 
A 1 23  CYS 23  193 193 CYS CYS D . n 
A 1 24  LYS 24  194 194 LYS LYS D . n 
A 1 25  PRO 25  195 195 PRO PRO D . n 
A 1 26  LYS 26  196 196 LYS LYS D . n 
A 1 27  VAL 27  197 197 VAL VAL D . n 
A 1 28  GLY 28  198 198 GLY GLY D . n 
A 1 29  TYR 29  199 199 TYR TYR D . n 
A 1 30  MET 30  200 200 MET MET D . n 
A 1 31  LYS 31  201 201 LYS LYS D . n 
A 1 32  LYS 32  202 202 LYS LYS D . n 
A 1 33  GLN 33  203 203 GLN GLN D . n 
A 1 34  PRO 34  204 204 PRO PRO D . n 
A 1 35  ASP 35  205 205 ASP ASP D . n 
A 1 36  ILE 36  206 206 ILE ILE D . n 
A 1 37  THR 37  207 207 THR THR D . n 
A 1 38  ASN 38  208 208 ASN ASN D . n 
A 1 39  SER 39  209 209 SER SER D . n 
A 1 40  MET 40  210 210 MET MET D . n 
A 1 41  ARG 41  211 211 ARG ARG D . n 
A 1 42  ALA 42  212 212 ALA ALA D . n 
A 1 43  ILE 43  213 213 ILE ILE D . n 
A 1 44  LEU 44  214 214 LEU LEU D . n 
A 1 45  VAL 45  215 215 VAL VAL D . n 
A 1 46  ASP 46  216 216 ASP ASP D . n 
A 1 47  TRP 47  217 217 TRP TRP D . n 
A 1 48  LEU 48  218 218 LEU LEU D . n 
A 1 49  VAL 49  219 219 VAL VAL D . n 
A 1 50  GLU 50  220 220 GLU GLU D . n 
A 1 51  VAL 51  221 221 VAL VAL D . n 
A 1 52  GLY 52  222 222 GLY GLY D . n 
A 1 53  GLU 53  223 223 GLU GLU D . n 
A 1 54  GLU 54  224 224 GLU GLU D . n 
A 1 55  TYR 55  225 225 TYR TYR D . n 
A 1 56  LYS 56  226 226 LYS LYS D . n 
A 1 57  LEU 57  227 227 LEU LEU D . n 
A 1 58  GLN 58  228 228 GLN GLN D . n 
A 1 59  ASN 59  229 229 ASN ASN D . n 
A 1 60  GLU 60  230 230 GLU GLU D . n 
A 1 61  THR 61  231 231 THR THR D . n 
A 1 62  LEU 62  232 232 LEU LEU D . n 
A 1 63  HIS 63  233 233 HIS HIS D . n 
A 1 64  LEU 64  234 234 LEU LEU D . n 
A 1 65  ALA 65  235 235 ALA ALA D . n 
A 1 66  VAL 66  236 236 VAL VAL D . n 
A 1 67  ASN 67  237 237 ASN ASN D . n 
A 1 68  TYR 68  238 238 TYR TYR D . n 
A 1 69  ILE 69  239 239 ILE ILE D . n 
A 1 70  ASP 70  240 240 ASP ASP D . n 
A 1 71  ARG 71  241 241 ARG ARG D . n 
A 1 72  PHE 72  242 242 PHE PHE D . n 
A 1 73  LEU 73  243 243 LEU LEU D . n 
A 1 74  SER 74  244 244 SER SER D . n 
A 1 75  SER 75  245 245 SER SER D . n 
A 1 76  MET 76  246 246 MET MET D . n 
A 1 77  SER 77  247 247 SER SER D . n 
A 1 78  VAL 78  248 248 VAL VAL D . n 
A 1 79  LEU 79  249 249 LEU LEU D . n 
A 1 80  ARG 80  250 250 ARG ARG D . n 
A 1 81  GLY 81  251 251 GLY GLY D . n 
A 1 82  LYS 82  252 252 LYS LYS D . n 
A 1 83  LEU 83  253 253 LEU LEU D . n 
A 1 84  GLN 84  254 254 GLN GLN D . n 
A 1 85  LEU 85  255 255 LEU LEU D . n 
A 1 86  VAL 86  256 256 VAL VAL D . n 
A 1 87  GLY 87  257 257 GLY GLY D . n 
A 1 88  THR 88  258 258 THR THR D . n 
A 1 89  ALA 89  259 259 ALA ALA D . n 
A 1 90  ALA 90  260 260 ALA ALA D . n 
A 1 91  MET 91  261 261 MET MET D . n 
A 1 92  LEU 92  262 262 LEU LEU D . n 
A 1 93  LEU 93  263 263 LEU LEU D . n 
A 1 94  ALA 94  264 264 ALA ALA D . n 
A 1 95  SER 95  265 265 SER SER D . n 
A 1 96  LYS 96  266 266 LYS LYS D . n 
A 1 97  PHE 97  267 267 PHE PHE D . n 
A 1 98  GLU 98  268 268 GLU GLU D . n 
A 1 99  GLU 99  269 269 GLU GLU D . n 
A 1 100 ILE 100 270 270 ILE ILE D . n 
A 1 101 TYR 101 271 271 TYR TYR D . n 
A 1 102 PRO 102 272 272 PRO PRO D . n 
A 1 103 PRO 103 273 273 PRO PRO D . n 
A 1 104 GLU 104 274 274 GLU GLU D . n 
A 1 105 VAL 105 275 275 VAL VAL D . n 
A 1 106 ALA 106 276 276 ALA ALA D . n 
A 1 107 GLU 107 277 277 GLU GLU D . n 
A 1 108 PHE 108 278 278 PHE PHE D . n 
A 1 109 VAL 109 279 279 VAL VAL D . n 
A 1 110 TYR 110 280 280 TYR TYR D . n 
A 1 111 ILE 111 281 281 ILE ILE D . n 
A 1 112 THR 112 282 282 THR THR D . n 
A 1 113 ASP 113 283 283 ASP ASP D . n 
A 1 114 ASP 114 284 284 ASP ASP D . n 
A 1 115 THR 115 285 285 THR THR D . n 
A 1 116 TYR 116 286 286 TYR TYR D . n 
A 1 117 THR 117 287 287 THR THR D . n 
A 1 118 LYS 118 288 288 LYS LYS D . n 
A 1 119 LYS 119 289 289 LYS LYS D . n 
A 1 120 GLN 120 290 290 GLN GLN D . n 
A 1 121 VAL 121 291 291 VAL VAL D . n 
A 1 122 LEU 122 292 292 LEU LEU D . n 
A 1 123 ARG 123 293 293 ARG ARG D . n 
A 1 124 MET 124 294 294 MET MET D . n 
A 1 125 GLU 125 295 295 GLU GLU D . n 
A 1 126 HIS 126 296 296 HIS HIS D . n 
A 1 127 LEU 127 297 297 LEU LEU D . n 
A 1 128 VAL 128 298 298 VAL VAL D . n 
A 1 129 LEU 129 299 299 LEU LEU D . n 
A 1 130 LYS 130 300 300 LYS LYS D . n 
A 1 131 VAL 131 301 301 VAL VAL D . n 
A 1 132 LEU 132 302 302 LEU LEU D . n 
A 1 133 ALA 133 303 303 ALA ALA D . n 
A 1 134 PHE 134 304 304 PHE PHE D . n 
A 1 135 ASP 135 305 305 ASP ASP D . n 
A 1 136 LEU 136 306 306 LEU LEU D . n 
A 1 137 ALA 137 307 307 ALA ALA D . n 
A 1 138 ALA 138 308 308 ALA ALA D . n 
A 1 139 PRO 139 309 309 PRO PRO D . n 
A 1 140 THR 140 310 310 THR THR D . n 
A 1 141 ILE 141 311 311 ILE ILE D . n 
A 1 142 ASN 142 312 312 ASN ASN D . n 
A 1 143 GLN 143 313 313 GLN GLN D . n 
A 1 144 PHE 144 314 314 PHE PHE D . n 
A 1 145 LEU 145 315 315 LEU LEU D . n 
A 1 146 THR 146 316 316 THR THR D . n 
A 1 147 GLN 147 317 317 GLN GLN D . n 
A 1 148 TYR 148 318 318 TYR TYR D . n 
A 1 149 PHE 149 319 319 PHE PHE D . n 
A 1 150 LEU 150 320 320 LEU LEU D . n 
A 1 151 HIS 151 321 321 HIS HIS D . n 
A 1 152 GLN 152 322 322 GLN GLN D . n 
A 1 153 GLN 153 323 323 GLN GLN D . n 
A 1 154 PRO 154 324 324 PRO PRO D . n 
A 1 155 ALA 155 325 325 ALA ALA D . n 
A 1 156 ASN 156 326 326 ASN ASN D . n 
A 1 157 CYS 157 327 327 CYS CYS D . n 
A 1 158 LYS 158 328 328 LYS LYS D . n 
A 1 159 VAL 159 329 329 VAL VAL D . n 
A 1 160 GLU 160 330 330 GLU GLU D . n 
A 1 161 SER 161 331 331 SER SER D . n 
A 1 162 LEU 162 332 332 LEU LEU D . n 
A 1 163 ALA 163 333 333 ALA ALA D . n 
A 1 164 MET 164 334 334 MET MET D . n 
A 1 165 PHE 165 335 335 PHE PHE D . n 
A 1 166 LEU 166 336 336 LEU LEU D . n 
A 1 167 GLY 167 337 337 GLY GLY D . n 
A 1 168 GLU 168 338 338 GLU GLU D . n 
A 1 169 LEU 169 339 339 LEU LEU D . n 
A 1 170 SER 170 340 340 SER SER D . n 
A 1 171 LEU 171 341 341 LEU LEU D . n 
A 1 172 ILE 172 342 342 ILE ILE D . n 
A 1 173 ASP 173 343 343 ASP ASP D . n 
A 1 174 ALA 174 344 344 ALA ALA D . n 
A 1 175 ASP 175 345 345 ASP ASP D . n 
A 1 176 PRO 176 346 346 PRO PRO D . n 
A 1 177 TYR 177 347 347 TYR TYR D . n 
A 1 178 LEU 178 348 348 LEU LEU D . n 
A 1 179 LYS 179 349 349 LYS LYS D . n 
A 1 180 TYR 180 350 350 TYR TYR D . n 
A 1 181 LEU 181 351 351 LEU LEU D . n 
A 1 182 PRO 182 352 352 PRO PRO D . n 
A 1 183 SER 183 353 353 SER SER D . n 
A 1 184 VAL 184 354 354 VAL VAL D . n 
A 1 185 ILE 185 355 355 ILE ILE D . n 
A 1 186 ALA 186 356 356 ALA ALA D . n 
A 1 187 ALA 187 357 357 ALA ALA D . n 
A 1 188 ALA 188 358 358 ALA ALA D . n 
A 1 189 ALA 189 359 359 ALA ALA D . n 
A 1 190 PHE 190 360 360 PHE PHE D . n 
A 1 191 HIS 191 361 361 HIS HIS D . n 
A 1 192 LEU 192 362 362 LEU LEU D . n 
A 1 193 ALA 193 363 363 ALA ALA D . n 
A 1 194 LEU 194 364 364 LEU LEU D . n 
A 1 195 TYR 195 365 365 TYR TYR D . n 
A 1 196 THR 196 366 366 THR THR D . n 
A 1 197 VAL 197 367 367 VAL VAL D . n 
A 1 198 THR 198 368 368 THR THR D . n 
A 1 199 GLY 199 369 369 GLY GLY D . n 
A 1 200 GLN 200 370 370 GLN GLN D . n 
A 1 201 SER 201 371 371 SER SER D . n 
A 1 202 TRP 202 372 372 TRP TRP D . n 
A 1 203 PRO 203 373 373 PRO PRO D . n 
A 1 204 GLU 204 374 374 GLU GLU D . n 
A 1 205 SER 205 375 375 SER SER D . n 
A 1 206 LEU 206 376 376 LEU LEU D . n 
A 1 207 VAL 207 377 377 VAL VAL D . n 
A 1 208 GLN 208 378 378 GLN GLN D . n 
A 1 209 LYS 209 379 379 LYS LYS D . n 
A 1 210 THR 210 380 380 THR THR D . n 
A 1 211 GLY 211 381 381 GLY GLY D . n 
A 1 212 TYR 212 382 382 TYR TYR D . n 
A 1 213 THR 213 383 383 THR THR D . n 
A 1 214 LEU 214 384 384 LEU LEU D . n 
A 1 215 GLU 215 385 385 GLU GLU D . n 
A 1 216 THR 216 386 386 THR THR D . n 
A 1 217 LEU 217 387 387 LEU LEU D . n 
A 1 218 LYS 218 388 388 LYS LYS D . n 
A 1 219 PRO 219 389 389 PRO PRO D . n 
A 1 220 CYS 220 390 390 CYS CYS D . n 
A 1 221 LEU 221 391 391 LEU LEU D . n 
A 1 222 LEU 222 392 392 LEU LEU D . n 
A 1 223 ASP 223 393 393 ASP ASP D . n 
A 1 224 LEU 224 394 394 LEU LEU D . n 
A 1 225 HIS 225 395 395 HIS HIS D . n 
A 1 226 GLN 226 396 396 GLN GLN D . n 
A 1 227 THR 227 397 397 THR THR D . n 
A 1 228 TYR 228 398 398 TYR TYR D . n 
A 1 229 LEU 229 399 399 LEU LEU D . n 
A 1 230 ARG 230 400 400 ARG ARG D . n 
A 1 231 ALA 231 401 401 ALA ALA D . n 
A 1 232 PRO 232 402 402 PRO PRO D . n 
A 1 233 GLN 233 403 403 GLN GLN D . n 
A 1 234 HIS 234 404 404 HIS HIS D . n 
A 1 235 ALA 235 405 405 ALA ALA D . n 
A 1 236 GLN 236 406 406 GLN GLN D . n 
A 1 237 GLN 237 407 407 GLN GLN D . n 
A 1 238 SER 238 408 408 SER SER D . n 
A 1 239 ILE 239 409 409 ILE ILE D . n 
A 1 240 ARG 240 410 410 ARG ARG D . n 
A 1 241 GLU 241 411 411 GLU GLU D . n 
A 1 242 LYS 242 412 412 LYS LYS D . n 
A 1 243 TYR 243 413 413 TYR TYR D . n 
A 1 244 LYS 244 414 414 LYS LYS D . n 
A 1 245 ASN 245 415 415 ASN ASN D . n 
A 1 246 SER 246 416 416 SER SER D . n 
A 1 247 LYS 247 417 417 LYS LYS D . n 
A 1 248 TYR 248 418 418 TYR TYR D . n 
A 1 249 HIS 249 419 419 HIS HIS D . n 
A 1 250 GLY 250 420 420 GLY GLY D . n 
A 1 251 VAL 251 421 421 VAL VAL D . n 
A 1 252 SER 252 422 422 SER SER D . n 
A 1 253 LEU 253 423 423 LEU LEU D . n 
A 1 254 LEU 254 424 424 LEU LEU D . n 
A 1 255 ASN 255 425 425 ASN ASN D . n 
A 1 256 PRO 256 426 426 PRO PRO D . n 
A 1 257 PRO 257 427 427 PRO PRO D . n 
A 1 258 GLU 258 428 428 GLU GLU D . n 
A 1 259 THR 259 429 429 THR THR D . n 
A 1 260 LEU 260 430 ?   ?   ?   D . n 
A 1 261 ASN 261 431 ?   ?   ?   D . n 
A 1 262 VAL 262 432 ?   ?   ?   D . n 
A 1 263 HIS 263 433 ?   ?   ?   D . n 
A 1 264 HIS 264 434 ?   ?   ?   D . n 
A 1 265 HIS 265 435 ?   ?   ?   D . n 
A 1 266 HIS 266 436 ?   ?   ?   D . n 
A 1 267 HIS 267 437 ?   ?   ?   D . n 
A 1 268 HIS 268 438 ?   ?   ?   D . n 
B 2 1   GLY 1   -3  -3  GLY GLY A . n 
B 2 2   PRO 2   -2  -2  PRO PRO A . n 
B 2 3   GLY 3   -1  -1  GLY GLY A . n 
B 2 4   SER 4   0   0   SER SER A . n 
B 2 5   MET 5   1   1   MET MET A . n 
B 2 6   GLU 6   2   2   GLU GLU A . n 
B 2 7   ASN 7   3   3   ASN ASN A . n 
B 2 8   PHE 8   4   4   PHE PHE A . n 
B 2 9   GLN 9   5   5   GLN GLN A . n 
B 2 10  LYS 10  6   6   LYS LYS A . n 
B 2 11  VAL 11  7   7   VAL VAL A . n 
B 2 12  GLU 12  8   8   GLU GLU A . n 
B 2 13  LYS 13  9   9   LYS LYS A . n 
B 2 14  ILE 14  10  10  ILE ILE A . n 
B 2 15  GLY 15  11  11  GLY GLY A . n 
B 2 16  GLU 16  12  12  GLU GLU A . n 
B 2 17  GLY 17  13  13  GLY GLY A . n 
B 2 18  THR 18  14  14  THR THR A . n 
B 2 19  TYR 19  15  15  TYR TYR A . n 
B 2 20  GLY 20  16  16  GLY GLY A . n 
B 2 21  VAL 21  17  17  VAL VAL A . n 
B 2 22  VAL 22  18  18  VAL VAL A . n 
B 2 23  TYR 23  19  19  TYR TYR A . n 
B 2 24  LYS 24  20  20  LYS LYS A . n 
B 2 25  ALA 25  21  21  ALA ALA A . n 
B 2 26  ARG 26  22  22  ARG ARG A . n 
B 2 27  ASN 27  23  23  ASN ASN A . n 
B 2 28  LYS 28  24  24  LYS LYS A . n 
B 2 29  LEU 29  25  25  LEU LEU A . n 
B 2 30  THR 30  26  26  THR THR A . n 
B 2 31  GLY 31  27  27  GLY GLY A . n 
B 2 32  GLU 32  28  28  GLU GLU A . n 
B 2 33  VAL 33  29  29  VAL VAL A . n 
B 2 34  VAL 34  30  30  VAL VAL A . n 
B 2 35  ALA 35  31  31  ALA ALA A . n 
B 2 36  LEU 36  32  32  LEU LEU A . n 
B 2 37  LYS 37  33  33  LYS LYS A . n 
B 2 38  LYS 38  34  34  LYS LYS A . n 
B 2 39  ILE 39  35  35  ILE ILE A . n 
B 2 40  ARG 40  36  36  ARG ARG A . n 
B 2 41  LEU 41  37  37  LEU LEU A . n 
B 2 42  ASP 42  38  ?   ?   ?   A . n 
B 2 43  THR 43  39  ?   ?   ?   A . n 
B 2 44  GLU 44  40  ?   ?   ?   A . n 
B 2 45  THR 45  41  ?   ?   ?   A . n 
B 2 46  GLU 46  42  42  GLU GLU A . n 
B 2 47  GLY 47  43  43  GLY GLY A . n 
B 2 48  VAL 48  44  44  VAL VAL A . n 
B 2 49  PRO 49  45  45  PRO PRO A . n 
B 2 50  SER 50  46  46  SER SER A . n 
B 2 51  THR 51  47  47  THR THR A . n 
B 2 52  ALA 52  48  48  ALA ALA A . n 
B 2 53  ILE 53  49  49  ILE ILE A . n 
B 2 54  ARG 54  50  50  ARG ARG A . n 
B 2 55  GLU 55  51  51  GLU GLU A . n 
B 2 56  ILE 56  52  52  ILE ILE A . n 
B 2 57  SER 57  53  53  SER SER A . n 
B 2 58  LEU 58  54  54  LEU LEU A . n 
B 2 59  LEU 59  55  55  LEU LEU A . n 
B 2 60  LYS 60  56  56  LYS LYS A . n 
B 2 61  GLU 61  57  57  GLU GLU A . n 
B 2 62  LEU 62  58  58  LEU LEU A . n 
B 2 63  ASN 63  59  59  ASN ASN A . n 
B 2 64  HIS 64  60  60  HIS HIS A . n 
B 2 65  PRO 65  61  61  PRO PRO A . n 
B 2 66  ASN 66  62  62  ASN ASN A . n 
B 2 67  ILE 67  63  63  ILE ILE A . n 
B 2 68  VAL 68  64  64  VAL VAL A . n 
B 2 69  LYS 69  65  65  LYS LYS A . n 
B 2 70  LEU 70  66  66  LEU LEU A . n 
B 2 71  LEU 71  67  67  LEU LEU A . n 
B 2 72  ASP 72  68  68  ASP ASP A . n 
B 2 73  VAL 73  69  69  VAL VAL A . n 
B 2 74  ILE 74  70  70  ILE ILE A . n 
B 2 75  HIS 75  71  71  HIS HIS A . n 
B 2 76  THR 76  72  72  THR THR A . n 
B 2 77  GLU 77  73  73  GLU GLU A . n 
B 2 78  ASN 78  74  74  ASN ASN A . n 
B 2 79  LYS 79  75  75  LYS LYS A . n 
B 2 80  LEU 80  76  76  LEU LEU A . n 
B 2 81  TYR 81  77  77  TYR TYR A . n 
B 2 82  LEU 82  78  78  LEU LEU A . n 
B 2 83  VAL 83  79  79  VAL VAL A . n 
B 2 84  PHE 84  80  80  PHE PHE A . n 
B 2 85  GLU 85  81  81  GLU GLU A . n 
B 2 86  PHE 86  82  82  PHE PHE A . n 
B 2 87  LEU 87  83  83  LEU LEU A . n 
B 2 88  HIS 88  84  84  HIS HIS A . n 
B 2 89  GLN 89  85  85  GLN GLN A . n 
B 2 90  ASP 90  86  86  ASP ASP A . n 
B 2 91  LEU 91  87  87  LEU LEU A . n 
B 2 92  LYS 92  88  88  LYS LYS A . n 
B 2 93  LYS 93  89  89  LYS LYS A . n 
B 2 94  PHE 94  90  90  PHE PHE A . n 
B 2 95  MET 95  91  91  MET MET A . n 
B 2 96  ASP 96  92  92  ASP ASP A . n 
B 2 97  ALA 97  93  93  ALA ALA A . n 
B 2 98  SER 98  94  94  SER SER A . n 
B 2 99  ALA 99  95  95  ALA ALA A . n 
B 2 100 LEU 100 96  96  LEU LEU A . n 
B 2 101 THR 101 97  97  THR THR A . n 
B 2 102 GLY 102 98  98  GLY GLY A . n 
B 2 103 ILE 103 99  99  ILE ILE A . n 
B 2 104 PRO 104 100 100 PRO PRO A . n 
B 2 105 LEU 105 101 101 LEU LEU A . n 
B 2 106 PRO 106 102 102 PRO PRO A . n 
B 2 107 LEU 107 103 103 LEU LEU A . n 
B 2 108 ILE 108 104 104 ILE ILE A . n 
B 2 109 LYS 109 105 105 LYS LYS A . n 
B 2 110 SER 110 106 106 SER SER A . n 
B 2 111 TYR 111 107 107 TYR TYR A . n 
B 2 112 LEU 112 108 108 LEU LEU A . n 
B 2 113 PHE 113 109 109 PHE PHE A . n 
B 2 114 GLN 114 110 110 GLN GLN A . n 
B 2 115 LEU 115 111 111 LEU LEU A . n 
B 2 116 LEU 116 112 112 LEU LEU A . n 
B 2 117 GLN 117 113 113 GLN GLN A . n 
B 2 118 GLY 118 114 114 GLY GLY A . n 
B 2 119 LEU 119 115 115 LEU LEU A . n 
B 2 120 ALA 120 116 116 ALA ALA A . n 
B 2 121 PHE 121 117 117 PHE PHE A . n 
B 2 122 CYS 122 118 118 CYS CYS A . n 
B 2 123 HIS 123 119 119 HIS HIS A . n 
B 2 124 SER 124 120 120 SER SER A . n 
B 2 125 HIS 125 121 121 HIS HIS A . n 
B 2 126 ARG 126 122 122 ARG ARG A . n 
B 2 127 VAL 127 123 123 VAL VAL A . n 
B 2 128 LEU 128 124 124 LEU LEU A . n 
B 2 129 HIS 129 125 125 HIS HIS A . n 
B 2 130 ARG 130 126 126 ARG ARG A . n 
B 2 131 ASP 131 127 127 ASP ASP A . n 
B 2 132 LEU 132 128 128 LEU LEU A . n 
B 2 133 LYS 133 129 129 LYS LYS A . n 
B 2 134 PRO 134 130 130 PRO PRO A . n 
B 2 135 GLN 135 131 131 GLN GLN A . n 
B 2 136 ASN 136 132 132 ASN ASN A . n 
B 2 137 LEU 137 133 133 LEU LEU A . n 
B 2 138 LEU 138 134 134 LEU LEU A . n 
B 2 139 ILE 139 135 135 ILE ILE A . n 
B 2 140 ASN 140 136 136 ASN ASN A . n 
B 2 141 THR 141 137 137 THR THR A . n 
B 2 142 GLU 142 138 138 GLU GLU A . n 
B 2 143 GLY 143 139 139 GLY GLY A . n 
B 2 144 ALA 144 140 140 ALA ALA A . n 
B 2 145 ILE 145 141 141 ILE ILE A . n 
B 2 146 LYS 146 142 142 LYS LYS A . n 
B 2 147 LEU 147 143 143 LEU LEU A . n 
B 2 148 ALA 148 144 144 ALA ALA A . n 
B 2 149 ASP 149 145 145 ASP ASP A . n 
B 2 150 PHE 150 146 146 PHE PHE A . n 
B 2 151 GLY 151 147 147 GLY GLY A . n 
B 2 152 LEU 152 148 148 LEU LEU A . n 
B 2 153 ALA 153 149 149 ALA ALA A . n 
B 2 154 ARG 154 150 150 ARG ARG A . n 
B 2 155 ALA 155 151 151 ALA ALA A . n 
B 2 156 PHE 156 152 152 PHE PHE A . n 
B 2 157 GLY 157 153 153 GLY GLY A . n 
B 2 158 VAL 158 154 154 VAL VAL A . n 
B 2 159 PRO 159 155 155 PRO PRO A . n 
B 2 160 VAL 160 156 156 VAL VAL A . n 
B 2 161 ARG 161 157 157 ARG ARG A . n 
B 2 162 THR 162 158 158 THR THR A . n 
B 2 163 TYR 163 159 159 TYR TYR A . n 
B 2 164 TPO 164 160 160 TPO TPO A . n 
B 2 165 HIS 165 161 161 HIS HIS A . n 
B 2 166 GLU 166 162 162 GLU GLU A . n 
B 2 167 VAL 167 163 163 VAL VAL A . n 
B 2 168 VAL 168 164 164 VAL VAL A . n 
B 2 169 THR 169 165 165 THR THR A . n 
B 2 170 LEU 170 166 166 LEU LEU A . n 
B 2 171 TRP 171 167 167 TRP TRP A . n 
B 2 172 TYR 172 168 168 TYR TYR A . n 
B 2 173 ARG 173 169 169 ARG ARG A . n 
B 2 174 ALA 174 170 170 ALA ALA A . n 
B 2 175 PRO 175 171 171 PRO PRO A . n 
B 2 176 GLU 176 172 172 GLU GLU A . n 
B 2 177 ILE 177 173 173 ILE ILE A . n 
B 2 178 LEU 178 174 174 LEU LEU A . n 
B 2 179 LEU 179 175 175 LEU LEU A . n 
B 2 180 GLY 180 176 176 GLY GLY A . n 
B 2 181 CYS 181 177 177 CYS CYS A . n 
B 2 182 LYS 182 178 178 LYS LYS A . n 
B 2 183 TYR 183 179 179 TYR TYR A . n 
B 2 184 TYR 184 180 180 TYR TYR A . n 
B 2 185 SER 185 181 181 SER SER A . n 
B 2 186 THR 186 182 182 THR THR A . n 
B 2 187 ALA 187 183 183 ALA ALA A . n 
B 2 188 VAL 188 184 184 VAL VAL A . n 
B 2 189 ASP 189 185 185 ASP ASP A . n 
B 2 190 ILE 190 186 186 ILE ILE A . n 
B 2 191 TRP 191 187 187 TRP TRP A . n 
B 2 192 SER 192 188 188 SER SER A . n 
B 2 193 LEU 193 189 189 LEU LEU A . n 
B 2 194 GLY 194 190 190 GLY GLY A . n 
B 2 195 CYS 195 191 191 CYS CYS A . n 
B 2 196 ILE 196 192 192 ILE ILE A . n 
B 2 197 PHE 197 193 193 PHE PHE A . n 
B 2 198 ALA 198 194 194 ALA ALA A . n 
B 2 199 GLU 199 195 195 GLU GLU A . n 
B 2 200 MET 200 196 196 MET MET A . n 
B 2 201 VAL 201 197 197 VAL VAL A . n 
B 2 202 THR 202 198 198 THR THR A . n 
B 2 203 ARG 203 199 199 ARG ARG A . n 
B 2 204 ARG 204 200 200 ARG ARG A . n 
B 2 205 ALA 205 201 201 ALA ALA A . n 
B 2 206 LEU 206 202 202 LEU LEU A . n 
B 2 207 PHE 207 203 203 PHE PHE A . n 
B 2 208 PRO 208 204 204 PRO PRO A . n 
B 2 209 GLY 209 205 205 GLY GLY A . n 
B 2 210 ASP 210 206 206 ASP ASP A . n 
B 2 211 SER 211 207 207 SER SER A . n 
B 2 212 GLU 212 208 208 GLU GLU A . n 
B 2 213 ILE 213 209 209 ILE ILE A . n 
B 2 214 ASP 214 210 210 ASP ASP A . n 
B 2 215 GLN 215 211 211 GLN GLN A . n 
B 2 216 LEU 216 212 212 LEU LEU A . n 
B 2 217 PHE 217 213 213 PHE PHE A . n 
B 2 218 ARG 218 214 214 ARG ARG A . n 
B 2 219 ILE 219 215 215 ILE ILE A . n 
B 2 220 PHE 220 216 216 PHE PHE A . n 
B 2 221 ARG 221 217 217 ARG ARG A . n 
B 2 222 THR 222 218 218 THR THR A . n 
B 2 223 LEU 223 219 219 LEU LEU A . n 
B 2 224 GLY 224 220 220 GLY GLY A . n 
B 2 225 THR 225 221 221 THR THR A . n 
B 2 226 PRO 226 222 222 PRO PRO A . n 
B 2 227 ASP 227 223 223 ASP ASP A . n 
B 2 228 GLU 228 224 224 GLU GLU A . n 
B 2 229 VAL 229 225 225 VAL VAL A . n 
B 2 230 VAL 230 226 226 VAL VAL A . n 
B 2 231 TRP 231 227 227 TRP TRP A . n 
B 2 232 PRO 232 228 228 PRO PRO A . n 
B 2 233 GLY 233 229 229 GLY GLY A . n 
B 2 234 VAL 234 230 230 VAL VAL A . n 
B 2 235 THR 235 231 231 THR THR A . n 
B 2 236 SER 236 232 232 SER SER A . n 
B 2 237 MET 237 233 233 MET MET A . n 
B 2 238 PRO 238 234 234 PRO PRO A . n 
B 2 239 ASP 239 235 235 ASP ASP A . n 
B 2 240 TYR 240 236 236 TYR TYR A . n 
B 2 241 LYS 241 237 237 LYS LYS A . n 
B 2 242 PRO 242 238 238 PRO PRO A . n 
B 2 243 SER 243 239 239 SER SER A . n 
B 2 244 PHE 244 240 240 PHE PHE A . n 
B 2 245 PRO 245 241 241 PRO PRO A . n 
B 2 246 LYS 246 242 242 LYS LYS A . n 
B 2 247 TRP 247 243 243 TRP TRP A . n 
B 2 248 ALA 248 244 244 ALA ALA A . n 
B 2 249 ARG 249 245 245 ARG ARG A . n 
B 2 250 GLN 250 246 246 GLN GLN A . n 
B 2 251 ASP 251 247 247 ASP ASP A . n 
B 2 252 PHE 252 248 248 PHE PHE A . n 
B 2 253 SER 253 249 249 SER SER A . n 
B 2 254 LYS 254 250 250 LYS LYS A . n 
B 2 255 VAL 255 251 251 VAL VAL A . n 
B 2 256 VAL 256 252 252 VAL VAL A . n 
B 2 257 PRO 257 253 253 PRO PRO A . n 
B 2 258 PRO 258 254 254 PRO PRO A . n 
B 2 259 LEU 259 255 255 LEU LEU A . n 
B 2 260 ASP 260 256 256 ASP ASP A . n 
B 2 261 GLU 261 257 257 GLU GLU A . n 
B 2 262 ASP 262 258 258 ASP ASP A . n 
B 2 263 GLY 263 259 259 GLY GLY A . n 
B 2 264 ARG 264 260 260 ARG ARG A . n 
B 2 265 SER 265 261 261 SER SER A . n 
B 2 266 LEU 266 262 262 LEU LEU A . n 
B 2 267 LEU 267 263 263 LEU LEU A . n 
B 2 268 SER 268 264 264 SER SER A . n 
B 2 269 GLN 269 265 265 GLN GLN A . n 
B 2 270 MET 270 266 266 MET MET A . n 
B 2 271 LEU 271 267 267 LEU LEU A . n 
B 2 272 HIS 272 268 268 HIS HIS A . n 
B 2 273 TYR 273 269 269 TYR TYR A . n 
B 2 274 ASP 274 270 270 ASP ASP A . n 
B 2 275 PRO 275 271 271 PRO PRO A . n 
B 2 276 ASN 276 272 272 ASN ASN A . n 
B 2 277 LYS 277 273 273 LYS LYS A . n 
B 2 278 ARG 278 274 274 ARG ARG A . n 
B 2 279 ILE 279 275 275 ILE ILE A . n 
B 2 280 SER 280 276 276 SER SER A . n 
B 2 281 ALA 281 277 277 ALA ALA A . n 
B 2 282 LYS 282 278 278 LYS LYS A . n 
B 2 283 ALA 283 279 279 ALA ALA A . n 
B 2 284 ALA 284 280 280 ALA ALA A . n 
B 2 285 LEU 285 281 281 LEU LEU A . n 
B 2 286 ALA 286 282 282 ALA ALA A . n 
B 2 287 HIS 287 283 283 HIS HIS A . n 
B 2 288 PRO 288 284 284 PRO PRO A . n 
B 2 289 PHE 289 285 285 PHE PHE A . n 
B 2 290 PHE 290 286 286 PHE PHE A . n 
B 2 291 GLN 291 287 287 GLN GLN A . n 
B 2 292 ASP 292 288 288 ASP ASP A . n 
B 2 293 VAL 293 289 289 VAL VAL A . n 
B 2 294 THR 294 290 290 THR THR A . n 
B 2 295 LYS 295 291 291 LYS LYS A . n 
B 2 296 PRO 296 292 292 PRO PRO A . n 
B 2 297 VAL 297 293 293 VAL VAL A . n 
B 2 298 PRO 298 294 294 PRO PRO A . n 
B 2 299 HIS 299 295 295 HIS HIS A . n 
B 2 300 LEU 300 296 296 LEU LEU A . n 
B 2 301 ARG 301 297 297 ARG ARG A . n 
B 2 302 LEU 302 298 ?   ?   ?   A . n 
C 1 1   GLY 1   171 171 GLY GLY B . n 
C 1 2   VAL 2   172 172 VAL VAL B . n 
C 1 3   ASN 3   173 173 ASN ASN B . n 
C 1 4   GLU 4   174 174 GLU GLU B . n 
C 1 5   VAL 5   175 175 VAL VAL B . n 
C 1 6   PRO 6   176 176 PRO PRO B . n 
C 1 7   ASP 7   177 177 ASP ASP B . n 
C 1 8   TYR 8   178 178 TYR TYR B . n 
C 1 9   HIS 9   179 179 HIS HIS B . n 
C 1 10  GLU 10  180 180 GLU GLU B . n 
C 1 11  ASP 11  181 181 ASP ASP B . n 
C 1 12  ILE 12  182 182 ILE ILE B . n 
C 1 13  HIS 13  183 183 HIS HIS B . n 
C 1 14  THR 14  184 184 THR THR B . n 
C 1 15  TYR 15  185 185 TYR TYR B . n 
C 1 16  LEU 16  186 186 LEU LEU B . n 
C 1 17  ARG 17  187 187 ARG ARG B . n 
C 1 18  GLU 18  188 188 GLU GLU B . n 
C 1 19  MET 19  189 189 MET MET B . n 
C 1 20  GLU 20  190 190 GLU GLU B . n 
C 1 21  VAL 21  191 191 VAL VAL B . n 
C 1 22  LYS 22  192 192 LYS LYS B . n 
C 1 23  CYS 23  193 193 CYS CYS B . n 
C 1 24  LYS 24  194 194 LYS LYS B . n 
C 1 25  PRO 25  195 195 PRO PRO B . n 
C 1 26  LYS 26  196 196 LYS LYS B . n 
C 1 27  VAL 27  197 197 VAL VAL B . n 
C 1 28  GLY 28  198 198 GLY GLY B . n 
C 1 29  TYR 29  199 199 TYR TYR B . n 
C 1 30  MET 30  200 200 MET MET B . n 
C 1 31  LYS 31  201 201 LYS LYS B . n 
C 1 32  LYS 32  202 202 LYS LYS B . n 
C 1 33  GLN 33  203 203 GLN GLN B . n 
C 1 34  PRO 34  204 204 PRO PRO B . n 
C 1 35  ASP 35  205 205 ASP ASP B . n 
C 1 36  ILE 36  206 206 ILE ILE B . n 
C 1 37  THR 37  207 207 THR THR B . n 
C 1 38  ASN 38  208 208 ASN ASN B . n 
C 1 39  SER 39  209 209 SER SER B . n 
C 1 40  MET 40  210 210 MET MET B . n 
C 1 41  ARG 41  211 211 ARG ARG B . n 
C 1 42  ALA 42  212 212 ALA ALA B . n 
C 1 43  ILE 43  213 213 ILE ILE B . n 
C 1 44  LEU 44  214 214 LEU LEU B . n 
C 1 45  VAL 45  215 215 VAL VAL B . n 
C 1 46  ASP 46  216 216 ASP ASP B . n 
C 1 47  TRP 47  217 217 TRP TRP B . n 
C 1 48  LEU 48  218 218 LEU LEU B . n 
C 1 49  VAL 49  219 219 VAL VAL B . n 
C 1 50  GLU 50  220 220 GLU GLU B . n 
C 1 51  VAL 51  221 221 VAL VAL B . n 
C 1 52  GLY 52  222 222 GLY GLY B . n 
C 1 53  GLU 53  223 223 GLU GLU B . n 
C 1 54  GLU 54  224 224 GLU GLU B . n 
C 1 55  TYR 55  225 225 TYR TYR B . n 
C 1 56  LYS 56  226 226 LYS LYS B . n 
C 1 57  LEU 57  227 227 LEU LEU B . n 
C 1 58  GLN 58  228 228 GLN GLN B . n 
C 1 59  ASN 59  229 229 ASN ASN B . n 
C 1 60  GLU 60  230 230 GLU GLU B . n 
C 1 61  THR 61  231 231 THR THR B . n 
C 1 62  LEU 62  232 232 LEU LEU B . n 
C 1 63  HIS 63  233 233 HIS HIS B . n 
C 1 64  LEU 64  234 234 LEU LEU B . n 
C 1 65  ALA 65  235 235 ALA ALA B . n 
C 1 66  VAL 66  236 236 VAL VAL B . n 
C 1 67  ASN 67  237 237 ASN ASN B . n 
C 1 68  TYR 68  238 238 TYR TYR B . n 
C 1 69  ILE 69  239 239 ILE ILE B . n 
C 1 70  ASP 70  240 240 ASP ASP B . n 
C 1 71  ARG 71  241 241 ARG ARG B . n 
C 1 72  PHE 72  242 242 PHE PHE B . n 
C 1 73  LEU 73  243 243 LEU LEU B . n 
C 1 74  SER 74  244 244 SER SER B . n 
C 1 75  SER 75  245 245 SER SER B . n 
C 1 76  MET 76  246 246 MET MET B . n 
C 1 77  SER 77  247 247 SER SER B . n 
C 1 78  VAL 78  248 248 VAL VAL B . n 
C 1 79  LEU 79  249 249 LEU LEU B . n 
C 1 80  ARG 80  250 250 ARG ARG B . n 
C 1 81  GLY 81  251 251 GLY GLY B . n 
C 1 82  LYS 82  252 252 LYS LYS B . n 
C 1 83  LEU 83  253 253 LEU LEU B . n 
C 1 84  GLN 84  254 254 GLN GLN B . n 
C 1 85  LEU 85  255 255 LEU LEU B . n 
C 1 86  VAL 86  256 256 VAL VAL B . n 
C 1 87  GLY 87  257 257 GLY GLY B . n 
C 1 88  THR 88  258 258 THR THR B . n 
C 1 89  ALA 89  259 259 ALA ALA B . n 
C 1 90  ALA 90  260 260 ALA ALA B . n 
C 1 91  MET 91  261 261 MET MET B . n 
C 1 92  LEU 92  262 262 LEU LEU B . n 
C 1 93  LEU 93  263 263 LEU LEU B . n 
C 1 94  ALA 94  264 264 ALA ALA B . n 
C 1 95  SER 95  265 265 SER SER B . n 
C 1 96  LYS 96  266 266 LYS LYS B . n 
C 1 97  PHE 97  267 267 PHE PHE B . n 
C 1 98  GLU 98  268 268 GLU GLU B . n 
C 1 99  GLU 99  269 269 GLU GLU B . n 
C 1 100 ILE 100 270 270 ILE ILE B . n 
C 1 101 TYR 101 271 271 TYR TYR B . n 
C 1 102 PRO 102 272 272 PRO PRO B . n 
C 1 103 PRO 103 273 273 PRO PRO B . n 
C 1 104 GLU 104 274 274 GLU GLU B . n 
C 1 105 VAL 105 275 275 VAL VAL B . n 
C 1 106 ALA 106 276 276 ALA ALA B . n 
C 1 107 GLU 107 277 277 GLU GLU B . n 
C 1 108 PHE 108 278 278 PHE PHE B . n 
C 1 109 VAL 109 279 279 VAL VAL B . n 
C 1 110 TYR 110 280 280 TYR TYR B . n 
C 1 111 ILE 111 281 281 ILE ILE B . n 
C 1 112 THR 112 282 282 THR THR B . n 
C 1 113 ASP 113 283 283 ASP ASP B . n 
C 1 114 ASP 114 284 284 ASP ASP B . n 
C 1 115 THR 115 285 285 THR THR B . n 
C 1 116 TYR 116 286 286 TYR TYR B . n 
C 1 117 THR 117 287 287 THR THR B . n 
C 1 118 LYS 118 288 288 LYS LYS B . n 
C 1 119 LYS 119 289 289 LYS LYS B . n 
C 1 120 GLN 120 290 290 GLN GLN B . n 
C 1 121 VAL 121 291 291 VAL VAL B . n 
C 1 122 LEU 122 292 292 LEU LEU B . n 
C 1 123 ARG 123 293 293 ARG ARG B . n 
C 1 124 MET 124 294 294 MET MET B . n 
C 1 125 GLU 125 295 295 GLU GLU B . n 
C 1 126 HIS 126 296 296 HIS HIS B . n 
C 1 127 LEU 127 297 297 LEU LEU B . n 
C 1 128 VAL 128 298 298 VAL VAL B . n 
C 1 129 LEU 129 299 299 LEU LEU B . n 
C 1 130 LYS 130 300 300 LYS LYS B . n 
C 1 131 VAL 131 301 301 VAL VAL B . n 
C 1 132 LEU 132 302 302 LEU LEU B . n 
C 1 133 ALA 133 303 303 ALA ALA B . n 
C 1 134 PHE 134 304 304 PHE PHE B . n 
C 1 135 ASP 135 305 305 ASP ASP B . n 
C 1 136 LEU 136 306 306 LEU LEU B . n 
C 1 137 ALA 137 307 307 ALA ALA B . n 
C 1 138 ALA 138 308 308 ALA ALA B . n 
C 1 139 PRO 139 309 309 PRO PRO B . n 
C 1 140 THR 140 310 310 THR THR B . n 
C 1 141 ILE 141 311 311 ILE ILE B . n 
C 1 142 ASN 142 312 312 ASN ASN B . n 
C 1 143 GLN 143 313 313 GLN GLN B . n 
C 1 144 PHE 144 314 314 PHE PHE B . n 
C 1 145 LEU 145 315 315 LEU LEU B . n 
C 1 146 THR 146 316 316 THR THR B . n 
C 1 147 GLN 147 317 317 GLN GLN B . n 
C 1 148 TYR 148 318 318 TYR TYR B . n 
C 1 149 PHE 149 319 319 PHE PHE B . n 
C 1 150 LEU 150 320 320 LEU LEU B . n 
C 1 151 HIS 151 321 321 HIS HIS B . n 
C 1 152 GLN 152 322 322 GLN GLN B . n 
C 1 153 GLN 153 323 323 GLN GLN B . n 
C 1 154 PRO 154 324 324 PRO PRO B . n 
C 1 155 ALA 155 325 325 ALA ALA B . n 
C 1 156 ASN 156 326 326 ASN ASN B . n 
C 1 157 CYS 157 327 327 CYS CYS B . n 
C 1 158 LYS 158 328 328 LYS LYS B . n 
C 1 159 VAL 159 329 329 VAL VAL B . n 
C 1 160 GLU 160 330 330 GLU GLU B . n 
C 1 161 SER 161 331 331 SER SER B . n 
C 1 162 LEU 162 332 332 LEU LEU B . n 
C 1 163 ALA 163 333 333 ALA ALA B . n 
C 1 164 MET 164 334 334 MET MET B . n 
C 1 165 PHE 165 335 335 PHE PHE B . n 
C 1 166 LEU 166 336 336 LEU LEU B . n 
C 1 167 GLY 167 337 337 GLY GLY B . n 
C 1 168 GLU 168 338 338 GLU GLU B . n 
C 1 169 LEU 169 339 339 LEU LEU B . n 
C 1 170 SER 170 340 340 SER SER B . n 
C 1 171 LEU 171 341 341 LEU LEU B . n 
C 1 172 ILE 172 342 342 ILE ILE B . n 
C 1 173 ASP 173 343 343 ASP ASP B . n 
C 1 174 ALA 174 344 344 ALA ALA B . n 
C 1 175 ASP 175 345 345 ASP ASP B . n 
C 1 176 PRO 176 346 346 PRO PRO B . n 
C 1 177 TYR 177 347 347 TYR TYR B . n 
C 1 178 LEU 178 348 348 LEU LEU B . n 
C 1 179 LYS 179 349 349 LYS LYS B . n 
C 1 180 TYR 180 350 350 TYR TYR B . n 
C 1 181 LEU 181 351 351 LEU LEU B . n 
C 1 182 PRO 182 352 352 PRO PRO B . n 
C 1 183 SER 183 353 353 SER SER B . n 
C 1 184 VAL 184 354 354 VAL VAL B . n 
C 1 185 ILE 185 355 355 ILE ILE B . n 
C 1 186 ALA 186 356 356 ALA ALA B . n 
C 1 187 ALA 187 357 357 ALA ALA B . n 
C 1 188 ALA 188 358 358 ALA ALA B . n 
C 1 189 ALA 189 359 359 ALA ALA B . n 
C 1 190 PHE 190 360 360 PHE PHE B . n 
C 1 191 HIS 191 361 361 HIS HIS B . n 
C 1 192 LEU 192 362 362 LEU LEU B . n 
C 1 193 ALA 193 363 363 ALA ALA B . n 
C 1 194 LEU 194 364 364 LEU LEU B . n 
C 1 195 TYR 195 365 365 TYR TYR B . n 
C 1 196 THR 196 366 366 THR THR B . n 
C 1 197 VAL 197 367 367 VAL VAL B . n 
C 1 198 THR 198 368 368 THR THR B . n 
C 1 199 GLY 199 369 369 GLY GLY B . n 
C 1 200 GLN 200 370 370 GLN GLN B . n 
C 1 201 SER 201 371 371 SER SER B . n 
C 1 202 TRP 202 372 372 TRP TRP B . n 
C 1 203 PRO 203 373 373 PRO PRO B . n 
C 1 204 GLU 204 374 374 GLU GLU B . n 
C 1 205 SER 205 375 375 SER SER B . n 
C 1 206 LEU 206 376 376 LEU LEU B . n 
C 1 207 VAL 207 377 377 VAL VAL B . n 
C 1 208 GLN 208 378 378 GLN GLN B . n 
C 1 209 LYS 209 379 379 LYS LYS B . n 
C 1 210 THR 210 380 380 THR THR B . n 
C 1 211 GLY 211 381 381 GLY GLY B . n 
C 1 212 TYR 212 382 382 TYR TYR B . n 
C 1 213 THR 213 383 383 THR THR B . n 
C 1 214 LEU 214 384 384 LEU LEU B . n 
C 1 215 GLU 215 385 385 GLU GLU B . n 
C 1 216 THR 216 386 386 THR THR B . n 
C 1 217 LEU 217 387 387 LEU LEU B . n 
C 1 218 LYS 218 388 388 LYS LYS B . n 
C 1 219 PRO 219 389 389 PRO PRO B . n 
C 1 220 CYS 220 390 390 CYS CYS B . n 
C 1 221 LEU 221 391 391 LEU LEU B . n 
C 1 222 LEU 222 392 392 LEU LEU B . n 
C 1 223 ASP 223 393 393 ASP ASP B . n 
C 1 224 LEU 224 394 394 LEU LEU B . n 
C 1 225 HIS 225 395 395 HIS HIS B . n 
C 1 226 GLN 226 396 396 GLN GLN B . n 
C 1 227 THR 227 397 397 THR THR B . n 
C 1 228 TYR 228 398 398 TYR TYR B . n 
C 1 229 LEU 229 399 399 LEU LEU B . n 
C 1 230 ARG 230 400 400 ARG ARG B . n 
C 1 231 ALA 231 401 401 ALA ALA B . n 
C 1 232 PRO 232 402 402 PRO PRO B . n 
C 1 233 GLN 233 403 403 GLN GLN B . n 
C 1 234 HIS 234 404 404 HIS HIS B . n 
C 1 235 ALA 235 405 405 ALA ALA B . n 
C 1 236 GLN 236 406 406 GLN GLN B . n 
C 1 237 GLN 237 407 407 GLN GLN B . n 
C 1 238 SER 238 408 408 SER SER B . n 
C 1 239 ILE 239 409 409 ILE ILE B . n 
C 1 240 ARG 240 410 410 ARG ARG B . n 
C 1 241 GLU 241 411 411 GLU GLU B . n 
C 1 242 LYS 242 412 412 LYS LYS B . n 
C 1 243 TYR 243 413 413 TYR TYR B . n 
C 1 244 LYS 244 414 414 LYS LYS B . n 
C 1 245 ASN 245 415 415 ASN ASN B . n 
C 1 246 SER 246 416 416 SER SER B . n 
C 1 247 LYS 247 417 417 LYS LYS B . n 
C 1 248 TYR 248 418 418 TYR TYR B . n 
C 1 249 HIS 249 419 419 HIS HIS B . n 
C 1 250 GLY 250 420 420 GLY GLY B . n 
C 1 251 VAL 251 421 421 VAL VAL B . n 
C 1 252 SER 252 422 422 SER SER B . n 
C 1 253 LEU 253 423 423 LEU LEU B . n 
C 1 254 LEU 254 424 424 LEU LEU B . n 
C 1 255 ASN 255 425 425 ASN ASN B . n 
C 1 256 PRO 256 426 426 PRO PRO B . n 
C 1 257 PRO 257 427 427 PRO PRO B . n 
C 1 258 GLU 258 428 428 GLU GLU B . n 
C 1 259 THR 259 429 429 THR THR B . n 
C 1 260 LEU 260 430 430 LEU LEU B . n 
C 1 261 ASN 261 431 431 ASN ASN B . n 
C 1 262 VAL 262 432 432 VAL VAL B . n 
C 1 263 HIS 263 433 ?   ?   ?   B . n 
C 1 264 HIS 264 434 ?   ?   ?   B . n 
C 1 265 HIS 265 435 ?   ?   ?   B . n 
C 1 266 HIS 266 436 ?   ?   ?   B . n 
C 1 267 HIS 267 437 ?   ?   ?   B . n 
C 1 268 HIS 268 438 ?   ?   ?   B . n 
D 2 1   GLY 1   -3  ?   ?   ?   C . n 
D 2 2   PRO 2   -2  ?   ?   ?   C . n 
D 2 3   GLY 3   -1  ?   ?   ?   C . n 
D 2 4   SER 4   0   0   SER SER C . n 
D 2 5   MET 5   1   1   MET MET C . n 
D 2 6   GLU 6   2   2   GLU GLU C . n 
D 2 7   ASN 7   3   3   ASN ASN C . n 
D 2 8   PHE 8   4   4   PHE PHE C . n 
D 2 9   GLN 9   5   5   GLN GLN C . n 
D 2 10  LYS 10  6   6   LYS LYS C . n 
D 2 11  VAL 11  7   7   VAL VAL C . n 
D 2 12  GLU 12  8   8   GLU GLU C . n 
D 2 13  LYS 13  9   9   LYS LYS C . n 
D 2 14  ILE 14  10  10  ILE ILE C . n 
D 2 15  GLY 15  11  11  GLY GLY C . n 
D 2 16  GLU 16  12  12  GLU GLU C . n 
D 2 17  GLY 17  13  13  GLY GLY C . n 
D 2 18  THR 18  14  14  THR THR C . n 
D 2 19  TYR 19  15  15  TYR TYR C . n 
D 2 20  GLY 20  16  16  GLY GLY C . n 
D 2 21  VAL 21  17  17  VAL VAL C . n 
D 2 22  VAL 22  18  18  VAL VAL C . n 
D 2 23  TYR 23  19  19  TYR TYR C . n 
D 2 24  LYS 24  20  20  LYS LYS C . n 
D 2 25  ALA 25  21  21  ALA ALA C . n 
D 2 26  ARG 26  22  22  ARG ARG C . n 
D 2 27  ASN 27  23  23  ASN ASN C . n 
D 2 28  LYS 28  24  24  LYS LYS C . n 
D 2 29  LEU 29  25  25  LEU LEU C . n 
D 2 30  THR 30  26  26  THR THR C . n 
D 2 31  GLY 31  27  27  GLY GLY C . n 
D 2 32  GLU 32  28  28  GLU GLU C . n 
D 2 33  VAL 33  29  29  VAL VAL C . n 
D 2 34  VAL 34  30  30  VAL VAL C . n 
D 2 35  ALA 35  31  31  ALA ALA C . n 
D 2 36  LEU 36  32  32  LEU LEU C . n 
D 2 37  LYS 37  33  33  LYS LYS C . n 
D 2 38  LYS 38  34  34  LYS LYS C . n 
D 2 39  ILE 39  35  35  ILE ILE C . n 
D 2 40  ARG 40  36  36  ARG ARG C . n 
D 2 41  LEU 41  37  37  LEU LEU C . n 
D 2 42  ASP 42  38  38  ASP ASP C . n 
D 2 43  THR 43  39  39  THR THR C . n 
D 2 44  GLU 44  40  40  GLU GLU C . n 
D 2 45  THR 45  41  41  THR THR C . n 
D 2 46  GLU 46  42  42  GLU GLU C . n 
D 2 47  GLY 47  43  43  GLY GLY C . n 
D 2 48  VAL 48  44  44  VAL VAL C . n 
D 2 49  PRO 49  45  45  PRO PRO C . n 
D 2 50  SER 50  46  46  SER SER C . n 
D 2 51  THR 51  47  47  THR THR C . n 
D 2 52  ALA 52  48  48  ALA ALA C . n 
D 2 53  ILE 53  49  49  ILE ILE C . n 
D 2 54  ARG 54  50  50  ARG ARG C . n 
D 2 55  GLU 55  51  51  GLU GLU C . n 
D 2 56  ILE 56  52  52  ILE ILE C . n 
D 2 57  SER 57  53  53  SER SER C . n 
D 2 58  LEU 58  54  54  LEU LEU C . n 
D 2 59  LEU 59  55  55  LEU LEU C . n 
D 2 60  LYS 60  56  56  LYS LYS C . n 
D 2 61  GLU 61  57  57  GLU GLU C . n 
D 2 62  LEU 62  58  58  LEU LEU C . n 
D 2 63  ASN 63  59  59  ASN ASN C . n 
D 2 64  HIS 64  60  60  HIS HIS C . n 
D 2 65  PRO 65  61  61  PRO PRO C . n 
D 2 66  ASN 66  62  62  ASN ASN C . n 
D 2 67  ILE 67  63  63  ILE ILE C . n 
D 2 68  VAL 68  64  64  VAL VAL C . n 
D 2 69  LYS 69  65  65  LYS LYS C . n 
D 2 70  LEU 70  66  66  LEU LEU C . n 
D 2 71  LEU 71  67  67  LEU LEU C . n 
D 2 72  ASP 72  68  68  ASP ASP C . n 
D 2 73  VAL 73  69  69  VAL VAL C . n 
D 2 74  ILE 74  70  70  ILE ILE C . n 
D 2 75  HIS 75  71  71  HIS HIS C . n 
D 2 76  THR 76  72  72  THR THR C . n 
D 2 77  GLU 77  73  73  GLU GLU C . n 
D 2 78  ASN 78  74  74  ASN ASN C . n 
D 2 79  LYS 79  75  75  LYS LYS C . n 
D 2 80  LEU 80  76  76  LEU LEU C . n 
D 2 81  TYR 81  77  77  TYR TYR C . n 
D 2 82  LEU 82  78  78  LEU LEU C . n 
D 2 83  VAL 83  79  79  VAL VAL C . n 
D 2 84  PHE 84  80  80  PHE PHE C . n 
D 2 85  GLU 85  81  81  GLU GLU C . n 
D 2 86  PHE 86  82  82  PHE PHE C . n 
D 2 87  LEU 87  83  83  LEU LEU C . n 
D 2 88  HIS 88  84  84  HIS HIS C . n 
D 2 89  GLN 89  85  85  GLN GLN C . n 
D 2 90  ASP 90  86  86  ASP ASP C . n 
D 2 91  LEU 91  87  87  LEU LEU C . n 
D 2 92  LYS 92  88  88  LYS LYS C . n 
D 2 93  LYS 93  89  89  LYS LYS C . n 
D 2 94  PHE 94  90  90  PHE PHE C . n 
D 2 95  MET 95  91  91  MET MET C . n 
D 2 96  ASP 96  92  92  ASP ASP C . n 
D 2 97  ALA 97  93  93  ALA ALA C . n 
D 2 98  SER 98  94  94  SER SER C . n 
D 2 99  ALA 99  95  95  ALA ALA C . n 
D 2 100 LEU 100 96  96  LEU LEU C . n 
D 2 101 THR 101 97  97  THR THR C . n 
D 2 102 GLY 102 98  98  GLY GLY C . n 
D 2 103 ILE 103 99  99  ILE ILE C . n 
D 2 104 PRO 104 100 100 PRO PRO C . n 
D 2 105 LEU 105 101 101 LEU LEU C . n 
D 2 106 PRO 106 102 102 PRO PRO C . n 
D 2 107 LEU 107 103 103 LEU LEU C . n 
D 2 108 ILE 108 104 104 ILE ILE C . n 
D 2 109 LYS 109 105 105 LYS LYS C . n 
D 2 110 SER 110 106 106 SER SER C . n 
D 2 111 TYR 111 107 107 TYR TYR C . n 
D 2 112 LEU 112 108 108 LEU LEU C . n 
D 2 113 PHE 113 109 109 PHE PHE C . n 
D 2 114 GLN 114 110 110 GLN GLN C . n 
D 2 115 LEU 115 111 111 LEU LEU C . n 
D 2 116 LEU 116 112 112 LEU LEU C . n 
D 2 117 GLN 117 113 113 GLN GLN C . n 
D 2 118 GLY 118 114 114 GLY GLY C . n 
D 2 119 LEU 119 115 115 LEU LEU C . n 
D 2 120 ALA 120 116 116 ALA ALA C . n 
D 2 121 PHE 121 117 117 PHE PHE C . n 
D 2 122 CYS 122 118 118 CYS CYS C . n 
D 2 123 HIS 123 119 119 HIS HIS C . n 
D 2 124 SER 124 120 120 SER SER C . n 
D 2 125 HIS 125 121 121 HIS HIS C . n 
D 2 126 ARG 126 122 122 ARG ARG C . n 
D 2 127 VAL 127 123 123 VAL VAL C . n 
D 2 128 LEU 128 124 124 LEU LEU C . n 
D 2 129 HIS 129 125 125 HIS HIS C . n 
D 2 130 ARG 130 126 126 ARG ARG C . n 
D 2 131 ASP 131 127 127 ASP ASP C . n 
D 2 132 LEU 132 128 128 LEU LEU C . n 
D 2 133 LYS 133 129 129 LYS LYS C . n 
D 2 134 PRO 134 130 130 PRO PRO C . n 
D 2 135 GLN 135 131 131 GLN GLN C . n 
D 2 136 ASN 136 132 132 ASN ASN C . n 
D 2 137 LEU 137 133 133 LEU LEU C . n 
D 2 138 LEU 138 134 134 LEU LEU C . n 
D 2 139 ILE 139 135 135 ILE ILE C . n 
D 2 140 ASN 140 136 136 ASN ASN C . n 
D 2 141 THR 141 137 137 THR THR C . n 
D 2 142 GLU 142 138 138 GLU GLU C . n 
D 2 143 GLY 143 139 139 GLY GLY C . n 
D 2 144 ALA 144 140 140 ALA ALA C . n 
D 2 145 ILE 145 141 141 ILE ILE C . n 
D 2 146 LYS 146 142 142 LYS LYS C . n 
D 2 147 LEU 147 143 143 LEU LEU C . n 
D 2 148 ALA 148 144 144 ALA ALA C . n 
D 2 149 ASP 149 145 145 ASP ASP C . n 
D 2 150 PHE 150 146 146 PHE PHE C . n 
D 2 151 GLY 151 147 147 GLY GLY C . n 
D 2 152 LEU 152 148 148 LEU LEU C . n 
D 2 153 ALA 153 149 149 ALA ALA C . n 
D 2 154 ARG 154 150 150 ARG ARG C . n 
D 2 155 ALA 155 151 151 ALA ALA C . n 
D 2 156 PHE 156 152 152 PHE PHE C . n 
D 2 157 GLY 157 153 153 GLY GLY C . n 
D 2 158 VAL 158 154 154 VAL VAL C . n 
D 2 159 PRO 159 155 155 PRO PRO C . n 
D 2 160 VAL 160 156 156 VAL VAL C . n 
D 2 161 ARG 161 157 157 ARG ARG C . n 
D 2 162 THR 162 158 158 THR THR C . n 
D 2 163 TYR 163 159 159 TYR TYR C . n 
D 2 164 TPO 164 160 160 TPO TPO C . n 
D 2 165 HIS 165 161 161 HIS HIS C . n 
D 2 166 GLU 166 162 162 GLU GLU C . n 
D 2 167 VAL 167 163 163 VAL VAL C . n 
D 2 168 VAL 168 164 164 VAL VAL C . n 
D 2 169 THR 169 165 165 THR THR C . n 
D 2 170 LEU 170 166 166 LEU LEU C . n 
D 2 171 TRP 171 167 167 TRP TRP C . n 
D 2 172 TYR 172 168 168 TYR TYR C . n 
D 2 173 ARG 173 169 169 ARG ARG C . n 
D 2 174 ALA 174 170 170 ALA ALA C . n 
D 2 175 PRO 175 171 171 PRO PRO C . n 
D 2 176 GLU 176 172 172 GLU GLU C . n 
D 2 177 ILE 177 173 173 ILE ILE C . n 
D 2 178 LEU 178 174 174 LEU LEU C . n 
D 2 179 LEU 179 175 175 LEU LEU C . n 
D 2 180 GLY 180 176 176 GLY GLY C . n 
D 2 181 CYS 181 177 177 CYS CYS C . n 
D 2 182 LYS 182 178 178 LYS LYS C . n 
D 2 183 TYR 183 179 179 TYR TYR C . n 
D 2 184 TYR 184 180 180 TYR TYR C . n 
D 2 185 SER 185 181 181 SER SER C . n 
D 2 186 THR 186 182 182 THR THR C . n 
D 2 187 ALA 187 183 183 ALA ALA C . n 
D 2 188 VAL 188 184 184 VAL VAL C . n 
D 2 189 ASP 189 185 185 ASP ASP C . n 
D 2 190 ILE 190 186 186 ILE ILE C . n 
D 2 191 TRP 191 187 187 TRP TRP C . n 
D 2 192 SER 192 188 188 SER SER C . n 
D 2 193 LEU 193 189 189 LEU LEU C . n 
D 2 194 GLY 194 190 190 GLY GLY C . n 
D 2 195 CYS 195 191 191 CYS CYS C . n 
D 2 196 ILE 196 192 192 ILE ILE C . n 
D 2 197 PHE 197 193 193 PHE PHE C . n 
D 2 198 ALA 198 194 194 ALA ALA C . n 
D 2 199 GLU 199 195 195 GLU GLU C . n 
D 2 200 MET 200 196 196 MET MET C . n 
D 2 201 VAL 201 197 197 VAL VAL C . n 
D 2 202 THR 202 198 198 THR THR C . n 
D 2 203 ARG 203 199 199 ARG ARG C . n 
D 2 204 ARG 204 200 200 ARG ARG C . n 
D 2 205 ALA 205 201 201 ALA ALA C . n 
D 2 206 LEU 206 202 202 LEU LEU C . n 
D 2 207 PHE 207 203 203 PHE PHE C . n 
D 2 208 PRO 208 204 204 PRO PRO C . n 
D 2 209 GLY 209 205 205 GLY GLY C . n 
D 2 210 ASP 210 206 206 ASP ASP C . n 
D 2 211 SER 211 207 207 SER SER C . n 
D 2 212 GLU 212 208 208 GLU GLU C . n 
D 2 213 ILE 213 209 209 ILE ILE C . n 
D 2 214 ASP 214 210 210 ASP ASP C . n 
D 2 215 GLN 215 211 211 GLN GLN C . n 
D 2 216 LEU 216 212 212 LEU LEU C . n 
D 2 217 PHE 217 213 213 PHE PHE C . n 
D 2 218 ARG 218 214 214 ARG ARG C . n 
D 2 219 ILE 219 215 215 ILE ILE C . n 
D 2 220 PHE 220 216 216 PHE PHE C . n 
D 2 221 ARG 221 217 217 ARG ARG C . n 
D 2 222 THR 222 218 218 THR THR C . n 
D 2 223 LEU 223 219 219 LEU LEU C . n 
D 2 224 GLY 224 220 220 GLY GLY C . n 
D 2 225 THR 225 221 221 THR THR C . n 
D 2 226 PRO 226 222 222 PRO PRO C . n 
D 2 227 ASP 227 223 223 ASP ASP C . n 
D 2 228 GLU 228 224 224 GLU GLU C . n 
D 2 229 VAL 229 225 225 VAL VAL C . n 
D 2 230 VAL 230 226 226 VAL VAL C . n 
D 2 231 TRP 231 227 227 TRP TRP C . n 
D 2 232 PRO 232 228 228 PRO PRO C . n 
D 2 233 GLY 233 229 229 GLY GLY C . n 
D 2 234 VAL 234 230 230 VAL VAL C . n 
D 2 235 THR 235 231 231 THR THR C . n 
D 2 236 SER 236 232 232 SER SER C . n 
D 2 237 MET 237 233 233 MET MET C . n 
D 2 238 PRO 238 234 234 PRO PRO C . n 
D 2 239 ASP 239 235 235 ASP ASP C . n 
D 2 240 TYR 240 236 236 TYR TYR C . n 
D 2 241 LYS 241 237 237 LYS LYS C . n 
D 2 242 PRO 242 238 238 PRO PRO C . n 
D 2 243 SER 243 239 ?   ?   ?   C . n 
D 2 244 PHE 244 240 ?   ?   ?   C . n 
D 2 245 PRO 245 241 ?   ?   ?   C . n 
D 2 246 LYS 246 242 ?   ?   ?   C . n 
D 2 247 TRP 247 243 ?   ?   ?   C . n 
D 2 248 ALA 248 244 ?   ?   ?   C . n 
D 2 249 ARG 249 245 ?   ?   ?   C . n 
D 2 250 GLN 250 246 ?   ?   ?   C . n 
D 2 251 ASP 251 247 ?   ?   ?   C . n 
D 2 252 PHE 252 248 ?   ?   ?   C . n 
D 2 253 SER 253 249 249 SER SER C . n 
D 2 254 LYS 254 250 250 LYS LYS C . n 
D 2 255 VAL 255 251 251 VAL VAL C . n 
D 2 256 VAL 256 252 252 VAL VAL C . n 
D 2 257 PRO 257 253 253 PRO PRO C . n 
D 2 258 PRO 258 254 254 PRO PRO C . n 
D 2 259 LEU 259 255 255 LEU LEU C . n 
D 2 260 ASP 260 256 256 ASP ASP C . n 
D 2 261 GLU 261 257 257 GLU GLU C . n 
D 2 262 ASP 262 258 258 ASP ASP C . n 
D 2 263 GLY 263 259 259 GLY GLY C . n 
D 2 264 ARG 264 260 260 ARG ARG C . n 
D 2 265 SER 265 261 261 SER SER C . n 
D 2 266 LEU 266 262 262 LEU LEU C . n 
D 2 267 LEU 267 263 263 LEU LEU C . n 
D 2 268 SER 268 264 264 SER SER C . n 
D 2 269 GLN 269 265 265 GLN GLN C . n 
D 2 270 MET 270 266 266 MET MET C . n 
D 2 271 LEU 271 267 267 LEU LEU C . n 
D 2 272 HIS 272 268 268 HIS HIS C . n 
D 2 273 TYR 273 269 269 TYR TYR C . n 
D 2 274 ASP 274 270 270 ASP ASP C . n 
D 2 275 PRO 275 271 271 PRO PRO C . n 
D 2 276 ASN 276 272 272 ASN ASN C . n 
D 2 277 LYS 277 273 273 LYS LYS C . n 
D 2 278 ARG 278 274 274 ARG ARG C . n 
D 2 279 ILE 279 275 275 ILE ILE C . n 
D 2 280 SER 280 276 276 SER SER C . n 
D 2 281 ALA 281 277 277 ALA ALA C . n 
D 2 282 LYS 282 278 278 LYS LYS C . n 
D 2 283 ALA 283 279 279 ALA ALA C . n 
D 2 284 ALA 284 280 280 ALA ALA C . n 
D 2 285 LEU 285 281 281 LEU LEU C . n 
D 2 286 ALA 286 282 282 ALA ALA C . n 
D 2 287 HIS 287 283 283 HIS HIS C . n 
D 2 288 PRO 288 284 284 PRO PRO C . n 
D 2 289 PHE 289 285 285 PHE PHE C . n 
D 2 290 PHE 290 286 286 PHE PHE C . n 
D 2 291 GLN 291 287 287 GLN GLN C . n 
D 2 292 ASP 292 288 288 ASP ASP C . n 
D 2 293 VAL 293 289 289 VAL VAL C . n 
D 2 294 THR 294 290 290 THR THR C . n 
D 2 295 LYS 295 291 291 LYS LYS C . n 
D 2 296 PRO 296 292 292 PRO PRO C . n 
D 2 297 VAL 297 293 293 VAL VAL C . n 
D 2 298 PRO 298 294 294 PRO PRO C . n 
D 2 299 HIS 299 295 295 HIS HIS C . n 
D 2 300 LEU 300 296 296 LEU LEU C . n 
D 2 301 ARG 301 297 ?   ?   ?   C . n 
D 2 302 LEU 302 298 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        HEW 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   HEW 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 HEW 1  601 601  HEW DRG D . 
F 3 HEW 1  801 801  HEW DRG A . 
G 3 HEW 1  802 1001 HEW DRG A . 
H 3 HEW 1  803 1101 HEW DRG A . 
I 3 HEW 1  804 1201 HEW DRG A . 
J 3 HEW 1  805 1301 HEW DRG A . 
K 3 HEW 1  801 801  HEW DRG B . 
L 3 HEW 1  802 901  HEW DRG B . 
M 3 HEW 1  701 701  HEW DRG C . 
N 3 HEW 1  702 901  HEW DRG C . 
O 4 HOH 1  701 511  HOH HOH D . 
O 4 HOH 2  702 429  HOH HOH D . 
O 4 HOH 3  703 502  HOH HOH D . 
O 4 HOH 4  704 512  HOH HOH D . 
O 4 HOH 5  705 548  HOH HOH D . 
O 4 HOH 6  706 529  HOH HOH D . 
O 4 HOH 7  707 521  HOH HOH D . 
O 4 HOH 8  708 490  HOH HOH D . 
O 4 HOH 9  709 551  HOH HOH D . 
O 4 HOH 10 710 492  HOH HOH D . 
O 4 HOH 11 711 520  HOH HOH D . 
O 4 HOH 12 712 557  HOH HOH D . 
O 4 HOH 13 713 470  HOH HOH D . 
O 4 HOH 14 714 538  HOH HOH D . 
O 4 HOH 15 715 562  HOH HOH D . 
O 4 HOH 16 716 533  HOH HOH D . 
O 4 HOH 17 717 561  HOH HOH D . 
O 4 HOH 18 718 553  HOH HOH D . 
O 4 HOH 19 719 627  HOH HOH D . 
O 4 HOH 20 720 497  HOH HOH D . 
O 4 HOH 21 721 558  HOH HOH D . 
O 4 HOH 22 722 531  HOH HOH D . 
O 4 HOH 23 723 471  HOH HOH D . 
O 4 HOH 24 724 520  HOH HOH D . 
P 4 HOH 1  901 468  HOH HOH A . 
P 4 HOH 2  902 436  HOH HOH A . 
P 4 HOH 3  903 475  HOH HOH A . 
P 4 HOH 4  904 614  HOH HOH A . 
P 4 HOH 5  905 537  HOH HOH A . 
P 4 HOH 6  906 599  HOH HOH A . 
P 4 HOH 7  907 421  HOH HOH A . 
P 4 HOH 8  908 440  HOH HOH A . 
P 4 HOH 9  909 415  HOH HOH A . 
P 4 HOH 10 910 527  HOH HOH A . 
P 4 HOH 11 911 444  HOH HOH A . 
P 4 HOH 12 912 545  HOH HOH A . 
P 4 HOH 13 913 504  HOH HOH A . 
P 4 HOH 14 914 433  HOH HOH A . 
P 4 HOH 15 915 432  HOH HOH A . 
P 4 HOH 16 916 416  HOH HOH A . 
P 4 HOH 17 917 430  HOH HOH A . 
P 4 HOH 18 918 425  HOH HOH A . 
P 4 HOH 19 919 523  HOH HOH A . 
P 4 HOH 20 920 428  HOH HOH A . 
P 4 HOH 21 921 629  HOH HOH A . 
P 4 HOH 22 922 442  HOH HOH A . 
P 4 HOH 23 923 459  HOH HOH A . 
P 4 HOH 24 924 524  HOH HOH A . 
P 4 HOH 25 925 474  HOH HOH A . 
P 4 HOH 26 926 574  HOH HOH A . 
P 4 HOH 27 927 448  HOH HOH A . 
P 4 HOH 28 928 559  HOH HOH A . 
P 4 HOH 29 929 490  HOH HOH A . 
P 4 HOH 30 930 465  HOH HOH A . 
P 4 HOH 31 931 457  HOH HOH A . 
P 4 HOH 32 932 470  HOH HOH A . 
P 4 HOH 33 933 461  HOH HOH A . 
P 4 HOH 34 934 488  HOH HOH A . 
P 4 HOH 35 935 483  HOH HOH A . 
P 4 HOH 36 936 509  HOH HOH A . 
P 4 HOH 37 937 424  HOH HOH A . 
P 4 HOH 38 938 529  HOH HOH A . 
P 4 HOH 39 939 433  HOH HOH A . 
P 4 HOH 40 940 447  HOH HOH A . 
P 4 HOH 41 941 478  HOH HOH A . 
P 4 HOH 42 942 562  HOH HOH A . 
P 4 HOH 43 943 501  HOH HOH A . 
P 4 HOH 44 944 479  HOH HOH A . 
P 4 HOH 45 945 532  HOH HOH A . 
P 4 HOH 46 946 469  HOH HOH A . 
P 4 HOH 47 947 511  HOH HOH A . 
P 4 HOH 48 948 589  HOH HOH A . 
P 4 HOH 49 949 482  HOH HOH A . 
P 4 HOH 50 950 522  HOH HOH A . 
P 4 HOH 51 951 500  HOH HOH A . 
P 4 HOH 52 952 431  HOH HOH A . 
P 4 HOH 53 953 466  HOH HOH A . 
P 4 HOH 54 954 571  HOH HOH A . 
P 4 HOH 55 955 527  HOH HOH A . 
P 4 HOH 56 956 544  HOH HOH A . 
P 4 HOH 57 957 515  HOH HOH A . 
P 4 HOH 58 958 464  HOH HOH A . 
P 4 HOH 59 959 509  HOH HOH A . 
P 4 HOH 60 960 417  HOH HOH A . 
P 4 HOH 61 961 503  HOH HOH A . 
P 4 HOH 62 962 522  HOH HOH A . 
P 4 HOH 63 963 484  HOH HOH A . 
P 4 HOH 64 964 553  HOH HOH A . 
P 4 HOH 65 965 556  HOH HOH A . 
P 4 HOH 66 966 469  HOH HOH A . 
P 4 HOH 67 967 541  HOH HOH A . 
P 4 HOH 68 968 483  HOH HOH A . 
P 4 HOH 69 969 576  HOH HOH A . 
P 4 HOH 70 970 495  HOH HOH A . 
P 4 HOH 71 971 533  HOH HOH A . 
P 4 HOH 72 972 462  HOH HOH A . 
P 4 HOH 73 973 485  HOH HOH A . 
P 4 HOH 74 974 569  HOH HOH A . 
P 4 HOH 75 975 546  HOH HOH A . 
P 4 HOH 76 976 500  HOH HOH A . 
P 4 HOH 77 977 573  HOH HOH A . 
P 4 HOH 78 978 526  HOH HOH A . 
P 4 HOH 79 979 570  HOH HOH A . 
P 4 HOH 80 980 455  HOH HOH A . 
P 4 HOH 81 981 532  HOH HOH A . 
P 4 HOH 82 982 503  HOH HOH A . 
P 4 HOH 83 983 504  HOH HOH A . 
P 4 HOH 84 984 628  HOH HOH A . 
P 4 HOH 85 985 551  HOH HOH A . 
P 4 HOH 86 986 611  HOH HOH A . 
P 4 HOH 87 987 552  HOH HOH A . 
P 4 HOH 88 988 464  HOH HOH A . 
P 4 HOH 89 989 489  HOH HOH A . 
P 4 HOH 90 990 467  HOH HOH A . 
P 4 HOH 91 991 482  HOH HOH A . 
P 4 HOH 92 992 545  HOH HOH A . 
P 4 HOH 93 993 588  HOH HOH A . 
Q 4 HOH 1  901 573  HOH HOH B . 
Q 4 HOH 2  902 521  HOH HOH B . 
Q 4 HOH 3  903 451  HOH HOH B . 
Q 4 HOH 4  904 524  HOH HOH B . 
Q 4 HOH 5  905 465  HOH HOH B . 
Q 4 HOH 6  906 509  HOH HOH B . 
Q 4 HOH 7  907 501  HOH HOH B . 
Q 4 HOH 8  908 563  HOH HOH B . 
Q 4 HOH 9  909 506  HOH HOH B . 
Q 4 HOH 10 910 606  HOH HOH B . 
Q 4 HOH 11 911 523  HOH HOH B . 
Q 4 HOH 12 912 558  HOH HOH B . 
Q 4 HOH 13 913 531  HOH HOH B . 
Q 4 HOH 14 914 547  HOH HOH B . 
Q 4 HOH 15 915 508  HOH HOH B . 
Q 4 HOH 16 916 522  HOH HOH B . 
Q 4 HOH 17 917 540  HOH HOH B . 
Q 4 HOH 18 918 617  HOH HOH B . 
Q 4 HOH 19 919 607  HOH HOH B . 
Q 4 HOH 20 920 622  HOH HOH B . 
Q 4 HOH 21 921 568  HOH HOH B . 
Q 4 HOH 22 922 520  HOH HOH B . 
Q 4 HOH 23 923 555  HOH HOH B . 
Q 4 HOH 24 924 532  HOH HOH B . 
Q 4 HOH 25 925 563  HOH HOH B . 
Q 4 HOH 26 926 546  HOH HOH B . 
Q 4 HOH 27 927 625  HOH HOH B . 
Q 4 HOH 28 928 530  HOH HOH B . 
Q 4 HOH 29 929 461  HOH HOH B . 
Q 4 HOH 30 930 534  HOH HOH B . 
Q 4 HOH 31 931 481  HOH HOH B . 
Q 4 HOH 32 932 549  HOH HOH B . 
Q 4 HOH 33 933 593  HOH HOH B . 
Q 4 HOH 34 934 542  HOH HOH B . 
Q 4 HOH 35 935 526  HOH HOH B . 
Q 4 HOH 36 936 557  HOH HOH B . 
Q 4 HOH 37 937 506  HOH HOH B . 
Q 4 HOH 38 938 552  HOH HOH B . 
Q 4 HOH 39 939 619  HOH HOH B . 
Q 4 HOH 40 940 607  HOH HOH B . 
Q 4 HOH 41 941 543  HOH HOH B . 
Q 4 HOH 42 942 560  HOH HOH B . 
Q 4 HOH 43 943 630  HOH HOH B . 
Q 4 HOH 44 944 512  HOH HOH B . 
Q 4 HOH 45 945 535  HOH HOH B . 
Q 4 HOH 46 946 430  HOH HOH B . 
Q 4 HOH 47 947 609  HOH HOH B . 
Q 4 HOH 48 948 460  HOH HOH B . 
Q 4 HOH 49 949 605  HOH HOH B . 
Q 4 HOH 50 950 628  HOH HOH B . 
Q 4 HOH 51 951 577  HOH HOH B . 
Q 4 HOH 52 952 636  HOH HOH B . 
Q 4 HOH 53 953 600  HOH HOH B . 
Q 4 HOH 54 954 615  HOH HOH B . 
Q 4 HOH 55 955 627  HOH HOH B . 
Q 4 HOH 56 956 596  HOH HOH B . 
Q 4 HOH 57 957 598  HOH HOH B . 
Q 4 HOH 58 958 619  HOH HOH B . 
Q 4 HOH 59 959 528  HOH HOH B . 
Q 4 HOH 60 960 641  HOH HOH B . 
Q 4 HOH 61 961 508  HOH HOH B . 
Q 4 HOH 62 962 537  HOH HOH B . 
Q 4 HOH 63 963 620  HOH HOH B . 
Q 4 HOH 64 964 595  HOH HOH B . 
Q 4 HOH 65 965 594  HOH HOH B . 
Q 4 HOH 66 966 639  HOH HOH B . 
Q 4 HOH 67 967 539  HOH HOH B . 
Q 4 HOH 68 968 582  HOH HOH B . 
Q 4 HOH 69 969 640  HOH HOH B . 
Q 4 HOH 70 970 565  HOH HOH B . 
Q 4 HOH 71 971 631  HOH HOH B . 
Q 4 HOH 72 972 663  HOH HOH B . 
Q 4 HOH 73 973 638  HOH HOH B . 
Q 4 HOH 74 974 623  HOH HOH B . 
Q 4 HOH 75 975 629  HOH HOH B . 
Q 4 HOH 76 976 512  HOH HOH B . 
Q 4 HOH 77 977 581  HOH HOH B . 
Q 4 HOH 78 978 657  HOH HOH B . 
Q 4 HOH 79 979 650  HOH HOH B . 
Q 4 HOH 80 980 648  HOH HOH B . 
Q 4 HOH 81 981 538  HOH HOH B . 
Q 4 HOH 82 982 676  HOH HOH B . 
Q 4 HOH 83 983 672  HOH HOH B . 
Q 4 HOH 84 984 618  HOH HOH B . 
R 4 HOH 1  801 414  HOH HOH C . 
R 4 HOH 2  802 516  HOH HOH C . 
R 4 HOH 3  803 556  HOH HOH C . 
R 4 HOH 4  804 463  HOH HOH C . 
R 4 HOH 5  805 538  HOH HOH C . 
R 4 HOH 6  806 438  HOH HOH C . 
R 4 HOH 7  807 410  HOH HOH C . 
R 4 HOH 8  808 479  HOH HOH C . 
R 4 HOH 9  809 572  HOH HOH C . 
R 4 HOH 10 810 430  HOH HOH C . 
R 4 HOH 11 811 474  HOH HOH C . 
R 4 HOH 12 812 566  HOH HOH C . 
R 4 HOH 13 813 406  HOH HOH C . 
R 4 HOH 14 814 554  HOH HOH C . 
R 4 HOH 15 815 432  HOH HOH C . 
R 4 HOH 16 816 426  HOH HOH C . 
R 4 HOH 17 817 564  HOH HOH C . 
R 4 HOH 18 818 428  HOH HOH C . 
R 4 HOH 19 819 544  HOH HOH C . 
R 4 HOH 20 820 552  HOH HOH C . 
R 4 HOH 21 821 528  HOH HOH C . 
R 4 HOH 22 822 543  HOH HOH C . 
R 4 HOH 23 823 525  HOH HOH C . 
R 4 HOH 24 824 465  HOH HOH C . 
R 4 HOH 25 825 601  HOH HOH C . 
R 4 HOH 26 826 427  HOH HOH C . 
R 4 HOH 27 827 453  HOH HOH C . 
R 4 HOH 28 828 610  HOH HOH C . 
R 4 HOH 29 829 445  HOH HOH C . 
R 4 HOH 30 830 529  HOH HOH C . 
R 4 HOH 31 831 504  HOH HOH C . 
R 4 HOH 32 832 616  HOH HOH C . 
R 4 HOH 33 833 443  HOH HOH C . 
R 4 HOH 34 834 575  HOH HOH C . 
R 4 HOH 35 835 592  HOH HOH C . 
R 4 HOH 36 836 457  HOH HOH C . 
R 4 HOH 37 837 475  HOH HOH C . 
R 4 HOH 38 838 558  HOH HOH C . 
R 4 HOH 39 839 450  HOH HOH C . 
R 4 HOH 40 840 446  HOH HOH C . 
R 4 HOH 41 841 461  HOH HOH C . 
R 4 HOH 42 842 476  HOH HOH C . 
R 4 HOH 43 843 477  HOH HOH C . 
R 4 HOH 44 844 473  HOH HOH C . 
R 4 HOH 45 845 511  HOH HOH C . 
R 4 HOH 46 846 515  HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ET9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.211 
_cell.length_a_esd                 ? 
_cell.length_b                     133.836 
_cell.length_b_esd                 ? 
_cell.length_c                     148.06 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ET9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ET9 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.92 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          57.83 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ET9 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.48 
_reflns.d_resolution_low                               148.06 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     49989 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           94.1 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.4 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.166 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.48 
_reflns_shell.d_res_low                                     2.56 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.7 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4832 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.746 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.5 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -2.200 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            2.633 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -0.434 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               63.320 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.949 
_refine.correlation_coeff_Fo_to_Fc_free          0.939 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ET9 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.494 
_refine.ls_d_res_low                             99.483 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     48487 
_refine.ls_number_reflns_R_free                  2479 
_refine.ls_number_reflns_R_work                  46008 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    92.892 
_refine.ls_percent_reflns_R_free                 5.113 
_refine.ls_R_factor_all                          0.225 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2457 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2240 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.239 
_refine.ls_wR_factor_R_work                      0.217 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.593 
_refine.pdbx_overall_ESU_R_Free                  0.287 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9404 
_refine.pdbx_average_fsc_free                    0.9361 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.494 
_refine_hist.d_res_low                        99.483 
_refine_hist.number_atoms_solvent             247 
_refine_hist.number_atoms_total               9204 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8877 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         80 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.012  9240  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.634  1.848  12550 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.053  5.000  1109  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 31.258 5.000  44    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.695 10.000 1603  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.375 10.000 396   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.101  0.200  1413  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  6936  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.228  0.200  4393  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.320  0.200  6236  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.156  0.200  360   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.314  0.200  58    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.313  0.200  7     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 3.170  6.204  4439  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.151  11.144 5547  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.350  6.452  4801  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.887  11.754 7003  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 10.153 67.160 14042 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.494  2.559  3838 . 155 3111 85.0964  . 1.409 . . 1.406 . . . . . 1.595 . 20 . 0.654 0.654 1.464 
'X-RAY DIFFRACTION' 2.559  2.629  3699 . 187 3512 100.0000 . 0.476 . . 0.475 . . . . . 0.479 . 20 . 0.905 0.888 0.512 
'X-RAY DIFFRACTION' 2.629  2.705  3577 . 94  1925 56.4439  . 0.357 . . 0.358 . . . . . 0.352 . 20 . 0.926 0.927 0.342 
'X-RAY DIFFRACTION' 2.705  2.788  3508 . 152 3356 100.0000 . 0.275 . . 0.274 . . . . . 0.265 . 20 . 0.950 0.945 0.303 
'X-RAY DIFFRACTION' 2.788  2.880  3410 . 174 3236 100.0000 . 0.271 . . 0.270 . . . . . 0.258 . 20 . 0.952 0.946 0.291 
'X-RAY DIFFRACTION' 2.880  2.981  3300 . 164 3136 100.0000 . 0.274 . . 0.272 . . . . . 0.260 . 20 . 0.952 0.938 0.319 
'X-RAY DIFFRACTION' 2.981  3.093  3185 . 184 3001 100.0000 . 0.259 . . 0.258 . . . . . 0.246 . 20 . 0.960 0.955 0.280 
'X-RAY DIFFRACTION' 3.093  3.219  3090 . 158 2932 100.0000 . 0.246 . . 0.246 . . . . . 0.233 . 20 . 0.962 0.960 0.250 
'X-RAY DIFFRACTION' 3.219  3.362  2930 . 148 2782 100.0000 . 0.233 . . 0.232 . . . . . 0.223 . 20 . 0.967 0.958 0.256 
'X-RAY DIFFRACTION' 3.362  3.526  2824 . 121 1926 72.4858  . 0.219 . . 0.218 . . . . . 0.207 . 20 . 0.971 0.967 0.235 
'X-RAY DIFFRACTION' 3.526  3.717  2698 . 110 2156 83.9881  . 0.208 . . 0.207 . . . . . 0.201 . 20 . 0.975 0.965 0.230 
'X-RAY DIFFRACTION' 3.717  3.942  2559 . 126 2081 86.2446  . 0.188 . . 0.186 . . . . . 0.182 . 20 . 0.980 0.969 0.219 
'X-RAY DIFFRACTION' 3.942  4.213  2381 . 128 2253 100.0000 . 0.171 . . 0.170 . . . . . 0.168 . 20 . 0.984 0.981 0.181 
'X-RAY DIFFRACTION' 4.213  4.550  2247 . 114 2133 100.0000 . 0.168 . . 0.166 . . . . . 0.165 . 20 . 0.984 0.974 0.204 
'X-RAY DIFFRACTION' 4.550  4.983  2098 . 114 1984 100.0000 . 0.171 . . 0.169 . . . . . 0.169 . 20 . 0.983 0.979 0.199 
'X-RAY DIFFRACTION' 4.983  5.570  1882 . 85  1797 100.0000 . 0.184 . . 0.183 . . . . . 0.183 . 20 . 0.981 0.979 0.201 
'X-RAY DIFFRACTION' 5.570  6.428  1683 . 84  1599 100.0000 . 0.213 . . 0.210 . . . . . 0.211 . 20 . 0.978 0.969 0.264 
'X-RAY DIFFRACTION' 6.428  7.865  1446 . 73  1373 100.0000 . 0.209 . . 0.210 . . . . . 0.214 . 20 . 0.978 0.982 0.197 
'X-RAY DIFFRACTION' 7.865  11.088 1144 . 63  1081 100.0000 . 0.153 . . 0.153 . . . . . 0.170 . 20 . 0.987 0.984 0.165 
'X-RAY DIFFRACTION' 11.088 99.483 682  . 45  635  99.7067  . 0.245 . . 0.243 . . . . . 0.287 . 20 . 0.957 0.960 0.279 
# 
_struct.entry_id                     9ET9 
_struct.title                        'CDK2-cyclin A in complex with FragLite 4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ET9 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
O N N 4 ? 
P N N 4 ? 
Q N N 4 ? 
R N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CCNA2_BOVIN P30274 ? 1 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
2 UNP CDK2_HUMAN  P24941 ? 2 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ET9 D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
2 2 9ET9 A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
3 1 9ET9 B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
4 2 9ET9 C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ET9 GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 1  
1 9ET9 HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 2  
1 9ET9 HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 3  
1 9ET9 HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 4  
1 9ET9 HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 5  
1 9ET9 HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 6  
1 9ET9 HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 7  
2 9ET9 GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  8  
2 9ET9 PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  9  
2 9ET9 GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  10 
2 9ET9 SER A 4   ? UNP P24941 ? ? 'expression tag' 0   11 
3 9ET9 GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 12 
3 9ET9 HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 13 
3 9ET9 HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 14 
3 9ET9 HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 15 
3 9ET9 HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 16 
3 9ET9 HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 17 
3 9ET9 HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 18 
4 9ET9 GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  19 
4 9ET9 PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  20 
4 9ET9 GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  21 
4 9ET9 SER C 4   ? UNP P24941 ? ? 'expression tag' 0   22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3780  ? 
1 MORE         -16   ? 
1 'SSA (A^2)'  22960 ? 
2 'ABSA (A^2)' 3430  ? 
2 MORE         -16   ? 
2 'SSA (A^2)'  23360 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E,M,N,O,R         
2 1 B,C,F,G,H,I,J,K,L,P,Q 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 1   ? VAL A 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P2  AA2 TYR A 8   ? CYS A 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P3  AA3 GLY A 28  ? GLN A 33  ? GLY D 198 GLN D 203 5 ? 6  
HELX_P HELX_P4  AA4 THR A 37  ? TYR A 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P5  AA5 GLN A 58  ? LEU A 73  ? GLN D 228 LEU D 243 1 ? 16 
HELX_P HELX_P6  AA6 LEU A 79  ? GLU A 99  ? LEU D 249 GLU D 269 1 ? 21 
HELX_P HELX_P7  AA7 GLU A 104 ? ILE A 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P8  AA8 THR A 117 ? LEU A 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P9  AA9 THR A 140 ? PHE A 149 ? THR D 310 PHE D 319 1 ? 10 
HELX_P HELX_P10 AB1 LEU A 150 ? GLN A 152 ? LEU D 320 GLN D 322 5 ? 3  
HELX_P HELX_P11 AB2 ASN A 156 ? ASP A 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P12 AB3 ASP A 173 ? LEU A 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P13 AB4 LEU A 181 ? GLY A 199 ? LEU D 351 GLY D 369 1 ? 19 
HELX_P HELX_P14 AB5 PRO A 203 ? GLY A 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P15 AB6 LEU A 217 ? ALA A 231 ? LEU D 387 ALA D 401 1 ? 15 
HELX_P HELX_P16 AB7 PRO A 232 ? HIS A 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P17 AB8 GLN A 237 ? TYR A 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P18 AB9 LYS A 244 ? HIS A 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P19 AC1 GLY A 250 ? LEU A 254 ? GLY D 420 LEU D 424 5 ? 5  
HELX_P HELX_P20 AC2 SER B 4   ? GLU B 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P21 AC3 PRO B 49  ? LEU B 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P22 AC4 LEU B 91  ? SER B 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P23 AC5 PRO B 104 ? HIS B 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P24 AC6 LYS B 133 ? GLN B 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P25 AC7 THR B 169 ? ARG B 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P26 AC8 ALA B 174 ? LEU B 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P27 AC9 THR B 186 ? ARG B 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P28 AD1 SER B 211 ? GLY B 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P29 AD2 GLY B 233 ? MET B 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P30 AD3 ASP B 251 ? VAL B 255 ? ASP A 247 VAL A 251 5 ? 5  
HELX_P HELX_P31 AD4 ASP B 260 ? LEU B 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P32 AD5 SER B 280 ? LEU B 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P33 AD6 ALA B 286 ? GLN B 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P34 AD7 GLY C 1   ? VAL C 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P35 AD8 TYR C 8   ? CYS C 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P36 AD9 THR C 37  ? LYS C 56  ? THR B 207 LYS B 226 1 ? 20 
HELX_P HELX_P37 AE1 GLN C 58  ? SER C 74  ? GLN B 228 SER B 244 1 ? 17 
HELX_P HELX_P38 AE2 LEU C 79  ? GLY C 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P39 AE3 LYS C 82  ? GLU C 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P40 AE4 GLU C 104 ? ILE C 111 ? GLU B 274 ILE B 281 1 ? 8  
HELX_P HELX_P41 AE5 THR C 117 ? ALA C 133 ? THR B 287 ALA B 303 1 ? 17 
HELX_P HELX_P42 AE6 THR C 140 ? LEU C 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P43 AE7 ASN C 156 ? ILE C 172 ? ASN B 326 ILE B 342 1 ? 17 
HELX_P HELX_P44 AE8 ASP C 173 ? LEU C 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P45 AE9 LEU C 181 ? GLY C 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P46 AF1 PRO C 203 ? GLY C 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P47 AF2 THR C 213 ? ALA C 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P48 AF3 GLN C 237 ? TYR C 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P49 AF4 LYS C 244 ? HIS C 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P50 AF5 GLY C 250 ? LEU C 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P51 AF6 PRO D 49  ? LEU D 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P52 AF7 LEU D 91  ? SER D 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P53 AF8 PRO D 104 ? HIS D 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P54 AF9 LYS D 133 ? GLN D 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P55 AG1 THR D 169 ? ARG D 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P56 AG2 ALA D 174 ? LEU D 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P57 AG3 THR D 186 ? ARG D 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P58 AG4 SER D 211 ? GLY D 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P59 AG5 GLY D 233 ? MET D 237 ? GLY C 229 MET C 233 5 ? 5  
HELX_P HELX_P60 AG6 ASP D 260 ? LEU D 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P61 AG7 SER D 280 ? LEU D 285 ? SER C 276 LEU C 281 1 ? 6  
HELX_P HELX_P62 AG8 ALA D 286 ? ASP D 292 ? ALA C 282 ASP C 288 5 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? B TYR 163 C ? ? ? 1_555 B TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale2 covale both ? B TPO 164 C ? ? ? 1_555 B HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.335 ? ? 
covale3 covale both ? D TYR 163 C ? ? ? 1_555 D TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.334 ? ? 
covale4 covale both ? D TPO 164 C ? ? ? 1_555 D HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.335 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO B 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO D 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 153 A . ? GLN 323 D PRO 154 A ? PRO 324 D 1 0.49   
2 ASP 175 A . ? ASP 345 D PRO 176 A ? PRO 346 D 1 3.48   
3 VAL 158 B . ? VAL 154 A PRO 159 B ? PRO 155 A 1 -12.07 
4 GLN 153 C . ? GLN 323 B PRO 154 C ? PRO 324 B 1 2.40   
5 ASP 175 C . ? ASP 345 B PRO 176 C ? PRO 346 B 1 5.38   
6 VAL 158 D . ? VAL 154 C PRO 159 D ? PRO 155 C 1 -3.30  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 8   ? GLY B 17  ? PHE A 4   GLY A 13  
AA1 2 GLY B 20  ? ASN B 27  ? GLY A 16  ASN A 23  
AA1 3 VAL B 33  ? ARG B 40  ? VAL A 29  ARG A 36  
AA1 4 LYS B 79  ? GLU B 85  ? LYS A 75  GLU A 81  
AA1 5 LEU B 70  ? THR B 76  ? LEU A 66  THR A 72  
AA2 1 GLN B 89  ? ASP B 90  ? GLN A 85  ASP A 86  
AA2 2 LEU B 137 ? ILE B 139 ? LEU A 133 ILE A 135 
AA2 3 ILE B 145 ? LEU B 147 ? ILE A 141 LEU A 143 
AA3 1 VAL B 127 ? LEU B 128 ? VAL A 123 LEU A 124 
AA3 2 ARG B 154 ? ALA B 155 ? ARG A 150 ALA A 151 
AA4 1 PHE D 8   ? GLU D 16  ? PHE C 4   GLU C 12  
AA4 2 VAL D 21  ? ASN D 27  ? VAL C 17  ASN C 23  
AA4 3 VAL D 33  ? ARG D 40  ? VAL C 29  ARG C 36  
AA4 4 LYS D 79  ? GLU D 85  ? LYS C 75  GLU C 81  
AA4 5 LEU D 70  ? HIS D 75  ? LEU C 66  HIS C 71  
AA5 1 GLN D 89  ? ASP D 90  ? GLN C 85  ASP C 86  
AA5 2 LEU D 137 ? ILE D 139 ? LEU C 133 ILE C 135 
AA5 3 ILE D 145 ? LEU D 147 ? ILE C 141 LEU C 143 
AA6 1 VAL D 127 ? LEU D 128 ? VAL C 123 LEU C 124 
AA6 2 ARG D 154 ? ALA D 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY B 17  ? N GLY A 13  O GLY B 20  ? O GLY A 16  
AA1 2 3 N TYR B 23  ? N TYR A 19  O LEU B 36  ? O LEU A 32  
AA1 3 4 N ALA B 35  ? N ALA A 31  O PHE B 84  ? O PHE A 80  
AA1 4 5 O VAL B 83  ? O VAL A 79  N LEU B 71  ? N LEU A 67  
AA2 1 2 N GLN B 89  ? N GLN A 85  O ILE B 139 ? O ILE A 135 
AA2 2 3 N LEU B 138 ? N LEU A 134 O LYS B 146 ? O LYS A 142 
AA3 1 2 N LEU B 128 ? N LEU A 124 O ARG B 154 ? O ARG A 150 
AA4 1 2 N GLY D 15  ? N GLY C 11  O VAL D 22  ? O VAL C 18  
AA4 2 3 N TYR D 23  ? N TYR C 19  O LEU D 36  ? O LEU C 32  
AA4 3 4 N ALA D 35  ? N ALA C 31  O PHE D 84  ? O PHE C 80  
AA4 4 5 O TYR D 81  ? O TYR C 77  N ILE D 74  ? N ILE C 70  
AA5 1 2 N GLN D 89  ? N GLN C 85  O ILE D 139 ? O ILE C 135 
AA5 2 3 N LEU D 138 ? N LEU C 134 O LYS D 146 ? O LYS C 142 
AA6 1 2 N LEU D 128 ? N LEU C 124 O ARG D 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ET9 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL D 175 ? ? 25.02   67.63   
2  1 GLN D 323 ? ? -168.29 109.05  
3  1 THR D 368 ? ? -135.56 -37.03  
4  1 TRP D 372 ? ? -29.40  106.86  
5  1 THR A 72  ? ? -88.44  -141.28 
6  1 LEU A 96  ? ? 81.89   -17.49  
7  1 THR A 97  ? ? -134.94 -39.11  
8  1 ASP A 127 ? ? -158.56 40.35   
9  1 ASP A 145 ? ? 53.45   84.64   
10 1 TYR A 159 ? ? -102.33 -169.17 
11 1 VAL A 164 ? ? 80.63   125.87  
12 1 SER A 181 ? ? -144.34 -156.29 
13 1 TRP B 372 ? ? -38.31  112.77  
14 1 THR C 41  ? ? -123.73 -86.09  
15 1 THR C 41  ? ? -123.73 -85.43  
16 1 ASP C 127 ? ? -154.26 45.13   
17 1 ASP C 145 ? ? 52.74   79.01   
18 1 GLU C 162 ? ? -65.70  76.76   
19 1 VAL C 164 ? ? 75.30   125.76  
20 1 HIS C 283 ? ? -31.75  128.79  
21 1 PHE C 286 ? ? -99.80  39.81   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG D 187 ? ? 0.146 'SIDE CHAIN' 
2  1 ARG D 241 ? ? 0.245 'SIDE CHAIN' 
3  1 ARG D 250 ? ? 0.179 'SIDE CHAIN' 
4  1 ARG A 36  ? ? 0.118 'SIDE CHAIN' 
5  1 ARG A 50  ? ? 0.161 'SIDE CHAIN' 
6  1 ARG A 122 ? ? 0.294 'SIDE CHAIN' 
7  1 ARG A 157 ? ? 0.229 'SIDE CHAIN' 
8  1 ARG A 200 ? ? 0.297 'SIDE CHAIN' 
9  1 ARG A 217 ? ? 0.091 'SIDE CHAIN' 
10 1 ARG A 297 ? ? 0.158 'SIDE CHAIN' 
11 1 ARG B 187 ? ? 0.084 'SIDE CHAIN' 
12 1 ARG B 211 ? ? 0.091 'SIDE CHAIN' 
13 1 ARG C 22  ? ? 0.167 'SIDE CHAIN' 
14 1 ARG C 36  ? ? 0.214 'SIDE CHAIN' 
15 1 ARG C 150 ? ? 0.296 'SIDE CHAIN' 
16 1 ARG C 217 ? ? 0.287 'SIDE CHAIN' 
# 
loop_
_pdbx_validate_main_chain_plane.id 
_pdbx_validate_main_chain_plane.PDB_model_num 
_pdbx_validate_main_chain_plane.auth_comp_id 
_pdbx_validate_main_chain_plane.auth_asym_id 
_pdbx_validate_main_chain_plane.auth_seq_id 
_pdbx_validate_main_chain_plane.PDB_ins_code 
_pdbx_validate_main_chain_plane.label_alt_id 
_pdbx_validate_main_chain_plane.improper_torsion_angle 
1 1 LEU A 83 ? ? -11.63 
2 1 HIS A 84 ? A -10.40 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 B TPO 164 A TPO 160 ? THR 'modified residue' 
2 D TPO 164 C TPO 160 ? THR 'modified residue' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 D LEU 430 ? A LEU 260 
2  1 Y 1 D ASN 431 ? A ASN 261 
3  1 Y 1 D VAL 432 ? A VAL 262 
4  1 Y 1 D HIS 433 ? A HIS 263 
5  1 Y 1 D HIS 434 ? A HIS 264 
6  1 Y 1 D HIS 435 ? A HIS 265 
7  1 Y 1 D HIS 436 ? A HIS 266 
8  1 Y 1 D HIS 437 ? A HIS 267 
9  1 Y 1 D HIS 438 ? A HIS 268 
10 1 Y 1 A ASP 38  ? B ASP 42  
11 1 Y 1 A THR 39  ? B THR 43  
12 1 Y 1 A GLU 40  ? B GLU 44  
13 1 Y 1 A THR 41  ? B THR 45  
14 1 Y 1 A LEU 298 ? B LEU 302 
15 1 Y 1 B HIS 433 ? C HIS 263 
16 1 Y 1 B HIS 434 ? C HIS 264 
17 1 Y 1 B HIS 435 ? C HIS 265 
18 1 Y 1 B HIS 436 ? C HIS 266 
19 1 Y 1 B HIS 437 ? C HIS 267 
20 1 Y 1 B HIS 438 ? C HIS 268 
21 1 Y 1 C GLY -3  ? D GLY 1   
22 1 Y 1 C PRO -2  ? D PRO 2   
23 1 Y 1 C GLY -1  ? D GLY 3   
24 1 Y 1 C SER 239 ? D SER 243 
25 1 Y 1 C PHE 240 ? D PHE 244 
26 1 Y 1 C PRO 241 ? D PRO 245 
27 1 Y 1 C LYS 242 ? D LYS 246 
28 1 Y 1 C TRP 243 ? D TRP 247 
29 1 Y 1 C ALA 244 ? D ALA 248 
30 1 Y 1 C ARG 245 ? D ARG 249 
31 1 Y 1 C GLN 246 ? D GLN 250 
32 1 Y 1 C ASP 247 ? D ASP 251 
33 1 Y 1 C PHE 248 ? D PHE 252 
34 1 Y 1 C ARG 297 ? D ARG 301 
35 1 Y 1 C LEU 298 ? D LEU 302 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HEW C4   C  Y N 137 
HEW C5   C  Y N 138 
HEW N1   N  N N 139 
HEW N2   N  Y N 140 
HEW C3   C  Y N 141 
HEW C1   C  Y N 142 
HEW C2   C  Y N 143 
HEW BR1  BR N N 144 
HEW H1   H  N N 145 
HEW H2   H  N N 146 
HEW H3   H  N N 147 
HEW H4   H  N N 148 
HEW H5   H  N N 149 
HIS N    N  N N 150 
HIS CA   C  N S 151 
HIS C    C  N N 152 
HIS O    O  N N 153 
HIS CB   C  N N 154 
HIS CG   C  Y N 155 
HIS ND1  N  Y N 156 
HIS CD2  C  Y N 157 
HIS CE1  C  Y N 158 
HIS NE2  N  Y N 159 
HIS OXT  O  N N 160 
HIS H    H  N N 161 
HIS H2   H  N N 162 
HIS HA   H  N N 163 
HIS HB2  H  N N 164 
HIS HB3  H  N N 165 
HIS HD1  H  N N 166 
HIS HD2  H  N N 167 
HIS HE1  H  N N 168 
HIS HE2  H  N N 169 
HIS HXT  H  N N 170 
HOH O    O  N N 171 
HOH H1   H  N N 172 
HOH H2   H  N N 173 
ILE N    N  N N 174 
ILE CA   C  N S 175 
ILE C    C  N N 176 
ILE O    O  N N 177 
ILE CB   C  N S 178 
ILE CG1  C  N N 179 
ILE CG2  C  N N 180 
ILE CD1  C  N N 181 
ILE OXT  O  N N 182 
ILE H    H  N N 183 
ILE H2   H  N N 184 
ILE HA   H  N N 185 
ILE HB   H  N N 186 
ILE HG12 H  N N 187 
ILE HG13 H  N N 188 
ILE HG21 H  N N 189 
ILE HG22 H  N N 190 
ILE HG23 H  N N 191 
ILE HD11 H  N N 192 
ILE HD12 H  N N 193 
ILE HD13 H  N N 194 
ILE HXT  H  N N 195 
LEU N    N  N N 196 
LEU CA   C  N S 197 
LEU C    C  N N 198 
LEU O    O  N N 199 
LEU CB   C  N N 200 
LEU CG   C  N N 201 
LEU CD1  C  N N 202 
LEU CD2  C  N N 203 
LEU OXT  O  N N 204 
LEU H    H  N N 205 
LEU H2   H  N N 206 
LEU HA   H  N N 207 
LEU HB2  H  N N 208 
LEU HB3  H  N N 209 
LEU HG   H  N N 210 
LEU HD11 H  N N 211 
LEU HD12 H  N N 212 
LEU HD13 H  N N 213 
LEU HD21 H  N N 214 
LEU HD22 H  N N 215 
LEU HD23 H  N N 216 
LEU HXT  H  N N 217 
LYS N    N  N N 218 
LYS CA   C  N S 219 
LYS C    C  N N 220 
LYS O    O  N N 221 
LYS CB   C  N N 222 
LYS CG   C  N N 223 
LYS CD   C  N N 224 
LYS CE   C  N N 225 
LYS NZ   N  N N 226 
LYS OXT  O  N N 227 
LYS H    H  N N 228 
LYS H2   H  N N 229 
LYS HA   H  N N 230 
LYS HB2  H  N N 231 
LYS HB3  H  N N 232 
LYS HG2  H  N N 233 
LYS HG3  H  N N 234 
LYS HD2  H  N N 235 
LYS HD3  H  N N 236 
LYS HE2  H  N N 237 
LYS HE3  H  N N 238 
LYS HZ1  H  N N 239 
LYS HZ2  H  N N 240 
LYS HZ3  H  N N 241 
LYS HXT  H  N N 242 
MET N    N  N N 243 
MET CA   C  N S 244 
MET C    C  N N 245 
MET O    O  N N 246 
MET CB   C  N N 247 
MET CG   C  N N 248 
MET SD   S  N N 249 
MET CE   C  N N 250 
MET OXT  O  N N 251 
MET H    H  N N 252 
MET H2   H  N N 253 
MET HA   H  N N 254 
MET HB2  H  N N 255 
MET HB3  H  N N 256 
MET HG2  H  N N 257 
MET HG3  H  N N 258 
MET HE1  H  N N 259 
MET HE2  H  N N 260 
MET HE3  H  N N 261 
MET HXT  H  N N 262 
PHE N    N  N N 263 
PHE CA   C  N S 264 
PHE C    C  N N 265 
PHE O    O  N N 266 
PHE CB   C  N N 267 
PHE CG   C  Y N 268 
PHE CD1  C  Y N 269 
PHE CD2  C  Y N 270 
PHE CE1  C  Y N 271 
PHE CE2  C  Y N 272 
PHE CZ   C  Y N 273 
PHE OXT  O  N N 274 
PHE H    H  N N 275 
PHE H2   H  N N 276 
PHE HA   H  N N 277 
PHE HB2  H  N N 278 
PHE HB3  H  N N 279 
PHE HD1  H  N N 280 
PHE HD2  H  N N 281 
PHE HE1  H  N N 282 
PHE HE2  H  N N 283 
PHE HZ   H  N N 284 
PHE HXT  H  N N 285 
PRO N    N  N N 286 
PRO CA   C  N S 287 
PRO C    C  N N 288 
PRO O    O  N N 289 
PRO CB   C  N N 290 
PRO CG   C  N N 291 
PRO CD   C  N N 292 
PRO OXT  O  N N 293 
PRO H    H  N N 294 
PRO HA   H  N N 295 
PRO HB2  H  N N 296 
PRO HB3  H  N N 297 
PRO HG2  H  N N 298 
PRO HG3  H  N N 299 
PRO HD2  H  N N 300 
PRO HD3  H  N N 301 
PRO HXT  H  N N 302 
SER N    N  N N 303 
SER CA   C  N S 304 
SER C    C  N N 305 
SER O    O  N N 306 
SER CB   C  N N 307 
SER OG   O  N N 308 
SER OXT  O  N N 309 
SER H    H  N N 310 
SER H2   H  N N 311 
SER HA   H  N N 312 
SER HB2  H  N N 313 
SER HB3  H  N N 314 
SER HG   H  N N 315 
SER HXT  H  N N 316 
THR N    N  N N 317 
THR CA   C  N S 318 
THR C    C  N N 319 
THR O    O  N N 320 
THR CB   C  N R 321 
THR OG1  O  N N 322 
THR CG2  C  N N 323 
THR OXT  O  N N 324 
THR H    H  N N 325 
THR H2   H  N N 326 
THR HA   H  N N 327 
THR HB   H  N N 328 
THR HG1  H  N N 329 
THR HG21 H  N N 330 
THR HG22 H  N N 331 
THR HG23 H  N N 332 
THR HXT  H  N N 333 
TPO N    N  N N 334 
TPO CA   C  N S 335 
TPO CB   C  N R 336 
TPO CG2  C  N N 337 
TPO OG1  O  N N 338 
TPO P    P  N N 339 
TPO O1P  O  N N 340 
TPO O2P  O  N N 341 
TPO O3P  O  N N 342 
TPO C    C  N N 343 
TPO O    O  N N 344 
TPO OXT  O  N N 345 
TPO H    H  N N 346 
TPO H2   H  N N 347 
TPO HA   H  N N 348 
TPO HB   H  N N 349 
TPO HG21 H  N N 350 
TPO HG22 H  N N 351 
TPO HG23 H  N N 352 
TPO HOP2 H  N N 353 
TPO HOP3 H  N N 354 
TPO HXT  H  N N 355 
TRP N    N  N N 356 
TRP CA   C  N S 357 
TRP C    C  N N 358 
TRP O    O  N N 359 
TRP CB   C  N N 360 
TRP CG   C  Y N 361 
TRP CD1  C  Y N 362 
TRP CD2  C  Y N 363 
TRP NE1  N  Y N 364 
TRP CE2  C  Y N 365 
TRP CE3  C  Y N 366 
TRP CZ2  C  Y N 367 
TRP CZ3  C  Y N 368 
TRP CH2  C  Y N 369 
TRP OXT  O  N N 370 
TRP H    H  N N 371 
TRP H2   H  N N 372 
TRP HA   H  N N 373 
TRP HB2  H  N N 374 
TRP HB3  H  N N 375 
TRP HD1  H  N N 376 
TRP HE1  H  N N 377 
TRP HE3  H  N N 378 
TRP HZ2  H  N N 379 
TRP HZ3  H  N N 380 
TRP HH2  H  N N 381 
TRP HXT  H  N N 382 
TYR N    N  N N 383 
TYR CA   C  N S 384 
TYR C    C  N N 385 
TYR O    O  N N 386 
TYR CB   C  N N 387 
TYR CG   C  Y N 388 
TYR CD1  C  Y N 389 
TYR CD2  C  Y N 390 
TYR CE1  C  Y N 391 
TYR CE2  C  Y N 392 
TYR CZ   C  Y N 393 
TYR OH   O  N N 394 
TYR OXT  O  N N 395 
TYR H    H  N N 396 
TYR H2   H  N N 397 
TYR HA   H  N N 398 
TYR HB2  H  N N 399 
TYR HB3  H  N N 400 
TYR HD1  H  N N 401 
TYR HD2  H  N N 402 
TYR HE1  H  N N 403 
TYR HE2  H  N N 404 
TYR HH   H  N N 405 
TYR HXT  H  N N 406 
VAL N    N  N N 407 
VAL CA   C  N S 408 
VAL C    C  N N 409 
VAL O    O  N N 410 
VAL CB   C  N N 411 
VAL CG1  C  N N 412 
VAL CG2  C  N N 413 
VAL OXT  O  N N 414 
VAL H    H  N N 415 
VAL H2   H  N N 416 
VAL HA   H  N N 417 
VAL HB   H  N N 418 
VAL HG11 H  N N 419 
VAL HG12 H  N N 420 
VAL HG13 H  N N 421 
VAL HG21 H  N N 422 
VAL HG22 H  N N 423 
VAL HG23 H  N N 424 
VAL HXT  H  N N 425 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HEW BR1 C3   sing N N 129 
HEW C4  C3   doub Y N 130 
HEW C4  C5   sing Y N 131 
HEW C3  C2   sing Y N 132 
HEW C5  N2   doub Y N 133 
HEW C2  C1   doub Y N 134 
HEW N2  C1   sing Y N 135 
HEW C1  N1   sing N N 136 
HEW C4  H1   sing N N 137 
HEW C5  H2   sing N N 138 
HEW N1  H3   sing N N 139 
HEW N1  H4   sing N N 140 
HEW C2  H5   sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PRO N   CA   sing N N 273 
PRO N   CD   sing N N 274 
PRO N   H    sing N N 275 
PRO CA  C    sing N N 276 
PRO CA  CB   sing N N 277 
PRO CA  HA   sing N N 278 
PRO C   O    doub N N 279 
PRO C   OXT  sing N N 280 
PRO CB  CG   sing N N 281 
PRO CB  HB2  sing N N 282 
PRO CB  HB3  sing N N 283 
PRO CG  CD   sing N N 284 
PRO CG  HG2  sing N N 285 
PRO CG  HG3  sing N N 286 
PRO CD  HD2  sing N N 287 
PRO CD  HD3  sing N N 288 
PRO OXT HXT  sing N N 289 
SER N   CA   sing N N 290 
SER N   H    sing N N 291 
SER N   H2   sing N N 292 
SER CA  C    sing N N 293 
SER CA  CB   sing N N 294 
SER CA  HA   sing N N 295 
SER C   O    doub N N 296 
SER C   OXT  sing N N 297 
SER CB  OG   sing N N 298 
SER CB  HB2  sing N N 299 
SER CB  HB3  sing N N 300 
SER OG  HG   sing N N 301 
SER OXT HXT  sing N N 302 
THR N   CA   sing N N 303 
THR N   H    sing N N 304 
THR N   H2   sing N N 305 
THR CA  C    sing N N 306 
THR CA  CB   sing N N 307 
THR CA  HA   sing N N 308 
THR C   O    doub N N 309 
THR C   OXT  sing N N 310 
THR CB  OG1  sing N N 311 
THR CB  CG2  sing N N 312 
THR CB  HB   sing N N 313 
THR OG1 HG1  sing N N 314 
THR CG2 HG21 sing N N 315 
THR CG2 HG22 sing N N 316 
THR CG2 HG23 sing N N 317 
THR OXT HXT  sing N N 318 
TPO N   CA   sing N N 319 
TPO N   H    sing N N 320 
TPO N   H2   sing N N 321 
TPO CA  CB   sing N N 322 
TPO CA  C    sing N N 323 
TPO CA  HA   sing N N 324 
TPO CB  CG2  sing N N 325 
TPO CB  OG1  sing N N 326 
TPO CB  HB   sing N N 327 
TPO CG2 HG21 sing N N 328 
TPO CG2 HG22 sing N N 329 
TPO CG2 HG23 sing N N 330 
TPO OG1 P    sing N N 331 
TPO P   O1P  doub N N 332 
TPO P   O2P  sing N N 333 
TPO P   O3P  sing N N 334 
TPO O2P HOP2 sing N N 335 
TPO O3P HOP3 sing N N 336 
TPO C   O    doub N N 337 
TPO C   OXT  sing N N 338 
TPO OXT HXT  sing N N 339 
TRP N   CA   sing N N 340 
TRP N   H    sing N N 341 
TRP N   H2   sing N N 342 
TRP CA  C    sing N N 343 
TRP CA  CB   sing N N 344 
TRP CA  HA   sing N N 345 
TRP C   O    doub N N 346 
TRP C   OXT  sing N N 347 
TRP CB  CG   sing N N 348 
TRP CB  HB2  sing N N 349 
TRP CB  HB3  sing N N 350 
TRP CG  CD1  doub Y N 351 
TRP CG  CD2  sing Y N 352 
TRP CD1 NE1  sing Y N 353 
TRP CD1 HD1  sing N N 354 
TRP CD2 CE2  doub Y N 355 
TRP CD2 CE3  sing Y N 356 
TRP NE1 CE2  sing Y N 357 
TRP NE1 HE1  sing N N 358 
TRP CE2 CZ2  sing Y N 359 
TRP CE3 CZ3  doub Y N 360 
TRP CE3 HE3  sing N N 361 
TRP CZ2 CH2  doub Y N 362 
TRP CZ2 HZ2  sing N N 363 
TRP CZ3 CH2  sing Y N 364 
TRP CZ3 HZ3  sing N N 365 
TRP CH2 HH2  sing N N 366 
TRP OXT HXT  sing N N 367 
TYR N   CA   sing N N 368 
TYR N   H    sing N N 369 
TYR N   H2   sing N N 370 
TYR CA  C    sing N N 371 
TYR CA  CB   sing N N 372 
TYR CA  HA   sing N N 373 
TYR C   O    doub N N 374 
TYR C   OXT  sing N N 375 
TYR CB  CG   sing N N 376 
TYR CB  HB2  sing N N 377 
TYR CB  HB3  sing N N 378 
TYR CG  CD1  doub Y N 379 
TYR CG  CD2  sing Y N 380 
TYR CD1 CE1  sing Y N 381 
TYR CD1 HD1  sing N N 382 
TYR CD2 CE2  doub Y N 383 
TYR CD2 HD2  sing N N 384 
TYR CE1 CZ   doub Y N 385 
TYR CE1 HE1  sing N N 386 
TYR CE2 CZ   sing Y N 387 
TYR CE2 HE2  sing N N 388 
TYR CZ  OH   sing N N 389 
TYR OH  HH   sing N N 390 
TYR OXT HXT  sing N N 391 
VAL N   CA   sing N N 392 
VAL N   H    sing N N 393 
VAL N   H2   sing N N 394 
VAL CA  C    sing N N 395 
VAL CA  CB   sing N N 396 
VAL CA  HA   sing N N 397 
VAL C   O    doub N N 398 
VAL C   OXT  sing N N 399 
VAL CB  CG1  sing N N 400 
VAL CB  CG2  sing N N 401 
VAL CB  HB   sing N N 402 
VAL CG1 HG11 sing N N 403 
VAL CG1 HG12 sing N N 404 
VAL CG1 HG13 sing N N 405 
VAL CG2 HG21 sing N N 406 
VAL CG2 HG22 sing N N 407 
VAL CG2 HG23 sing N N 408 
VAL OXT HXT  sing N N 409 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ET9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013475 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007472 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006754 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 -0.0527  
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P  15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLY A 1 1   ? -65.264 0.536   31.902  1   101.64 ? 171 GLY D N   1 
ATOM   2    C  CA  . GLY A 1 1   ? -64.817 1.94    31.97   1   102.05 ? 171 GLY D CA  1 
ATOM   3    C  C   . GLY A 1 1   ? -63.323 2.095   31.664  1   99.82  ? 171 GLY D C   1 
ATOM   4    O  O   . GLY A 1 1   ? -62.712 1.283   30.957  1   96.03  ? 171 GLY D O   1 
ATOM   5    N  N   . VAL A 1 2   ? -62.74  3.166   32.216  1   94.45  ? 172 VAL D N   1 
ATOM   6    C  CA  . VAL A 1 2   ? -61.446 3.626   31.757  1   86.62  ? 172 VAL D CA  1 
ATOM   7    C  C   . VAL A 1 2   ? -60.391 2.624   32.209  1   83.74  ? 172 VAL D C   1 
ATOM   8    O  O   . VAL A 1 2   ? -59.299 2.61    31.66   1   83.7   ? 172 VAL D O   1 
ATOM   9    C  CB  . VAL A 1 2   ? -61.094 5.064   32.18   1   84.57  ? 172 VAL D CB  1 
ATOM   10   C  CG1 . VAL A 1 2   ? -60.59  5.128   33.616  1   82.75  ? 172 VAL D CG1 1 
ATOM   11   C  CG2 . VAL A 1 2   ? -60.076 5.7     31.24   1   81.46  ? 172 VAL D CG2 1 
ATOM   12   N  N   . ASN A 1 3   ? -60.723 1.832   33.219  1   82.61  ? 173 ASN D N   1 
ATOM   13   C  CA  . ASN A 1 3   ? -59.757 0.851   33.767  1   80     ? 173 ASN D CA  1 
ATOM   14   C  C   . ASN A 1 3   ? -59.563 -0.282  32.757  1   78.64  ? 173 ASN D C   1 
ATOM   15   O  O   . ASN A 1 3   ? -58.65  -1.095  32.956  1   75.58  ? 173 ASN D O   1 
ATOM   16   C  CB  . ASN A 1 3   ? -60.215 0.394   35.144  1   82.9   ? 173 ASN D CB  1 
ATOM   17   C  CG  . ASN A 1 3   ? -60.295 1.538   36.124  1   86.29  ? 173 ASN D CG  1 
ATOM   18   O  OD1 . ASN A 1 3   ? -59.661 2.578   35.92   1   85.01  ? 173 ASN D OD1 1 
ATOM   19   N  ND2 . ASN A 1 3   ? -61.063 1.369   37.189  1   91.91  ? 173 ASN D ND2 1 
ATOM   20   N  N   . GLU A 1 4   ? -60.381 -0.317  31.707  1   81.78  ? 174 GLU D N   1 
ATOM   21   C  CA  . GLU A 1 4   ? -60.237 -1.349  30.653  1   83.28  ? 174 GLU D CA  1 
ATOM   22   C  C   . GLU A 1 4   ? -59.736 -0.656  29.387  1   82.84  ? 174 GLU D C   1 
ATOM   23   O  O   . GLU A 1 4   ? -59.902 -1.229  28.297  1   81.95  ? 174 GLU D O   1 
ATOM   24   C  CB  . GLU A 1 4   ? -61.567 -2.061  30.441  1   89.98  ? 174 GLU D CB  1 
ATOM   25   C  CG  . GLU A 1 4   ? -62.026 -2.843  31.668  1   92.65  ? 174 GLU D CG  1 
ATOM   26   C  CD  . GLU A 1 4   ? -63.476 -3.282  31.599  1   98.08  ? 174 GLU D CD  1 
ATOM   27   O  OE1 . GLU A 1 4   ? -64.25  -2.639  30.863  1   98.49  ? 174 GLU D OE1 1 
ATOM   28   O  OE2 . GLU A 1 4   ? -63.83  -4.265  32.281  1   101.28 ? 174 GLU D OE2 1 
ATOM   29   N  N   . VAL A 1 5   ? -59.136 0.523   29.543  1   83.98  ? 175 VAL D N   1 
ATOM   30   C  CA  . VAL A 1 5   ? -58.573 1.306   28.398  1   81.93  ? 175 VAL D CA  1 
ATOM   31   C  C   . VAL A 1 5   ? -59.271 0.955   27.074  1   83.51  ? 175 VAL D C   1 
ATOM   32   O  O   . VAL A 1 5   ? -58.6   0.446   26.155  1   81.01  ? 175 VAL D O   1 
ATOM   33   C  CB  . VAL A 1 5   ? -57.043 1.128   28.331  1   74.79  ? 175 VAL D CB  1 
ATOM   34   C  CG1 . VAL A 1 5   ? -56.353 1.996   29.372  1   69.95  ? 175 VAL D CG1 1 
ATOM   35   C  CG2 . VAL A 1 5   ? -56.607 -0.323  28.493  1   71.04  ? 175 VAL D CG2 1 
ATOM   36   N  N   . PRO A 1 6   ? -60.562 1.3     26.906  1   87.82  ? 176 PRO D N   1 
ATOM   37   C  CA  . PRO A 1 6   ? -61.289 0.94    25.698  1   89.83  ? 176 PRO D CA  1 
ATOM   38   C  C   . PRO A 1 6   ? -60.656 1.415   24.398  1   90.06  ? 176 PRO D C   1 
ATOM   39   O  O   . PRO A 1 6   ? -60.591 0.632   23.437  1   89.85  ? 176 PRO D O   1 
ATOM   40   C  CB  . PRO A 1 6   ? -62.651 1.596   25.947  1   92.05  ? 176 PRO D CB  1 
ATOM   41   C  CG  . PRO A 1 6   ? -62.392 2.672   26.967  1   90.36  ? 176 PRO D CG  1 
ATOM   42   C  CD  . PRO A 1 6   ? -61.347 2.056   27.861  1   89.68  ? 176 PRO D CD  1 
ATOM   43   N  N   . ASP A 1 7   ? -60.174 2.655   24.365  1   89.29  ? 177 ASP D N   1 
ATOM   44   C  CA  . ASP A 1 7   ? -59.625 3.216   23.103  1   88.68  ? 177 ASP D CA  1 
ATOM   45   C  C   . ASP A 1 7   ? -58.224 2.67    22.813  1   84.17  ? 177 ASP D C   1 
ATOM   46   O  O   . ASP A 1 7   ? -57.635 3.111   21.814  1   82.23  ? 177 ASP D O   1 
ATOM   47   C  CB  . ASP A 1 7   ? -59.593 4.735   23.127  1   93.32  ? 177 ASP D CB  1 
ATOM   48   C  CG  . ASP A 1 7   ? -60.937 5.444   23.045  1   98.64  ? 177 ASP D CG  1 
ATOM   49   O  OD1 . ASP A 1 7   ? -61.93  4.785   22.683  1   100.92 ? 177 ASP D OD1 1 
ATOM   50   O  OD2 . ASP A 1 7   ? -60.976 6.65    23.36   1   99.92  ? 177 ASP D OD2 1 
ATOM   51   N  N   . TYR A 1 8   ? -57.711 1.75    23.635  1   80.97  ? 178 TYR D N   1 
ATOM   52   C  CA  . TYR A 1 8   ? -56.316 1.269   23.446  1   77.45  ? 178 TYR D CA  1 
ATOM   53   C  C   . TYR A 1 8   ? -56.245 -0.245  23.564  1   80.05  ? 178 TYR D C   1 
ATOM   54   O  O   . TYR A 1 8   ? -55.248 -0.827  23.103  1   79.3   ? 178 TYR D O   1 
ATOM   55   C  CB  . TYR A 1 8   ? -55.44  1.955   24.496  1   71.37  ? 178 TYR D CB  1 
ATOM   56   C  CG  . TYR A 1 8   ? -55.365 3.471   24.4    1   71.22  ? 178 TYR D CG  1 
ATOM   57   C  CD1 . TYR A 1 8   ? -54.672 4.091   23.37   1   71.21  ? 178 TYR D CD1 1 
ATOM   58   C  CD2 . TYR A 1 8   ? -55.987 4.278   25.342  1   73.8   ? 178 TYR D CD2 1 
ATOM   59   C  CE1 . TYR A 1 8   ? -54.602 5.47    23.277  1   75.05  ? 178 TYR D CE1 1 
ATOM   60   C  CE2 . TYR A 1 8   ? -55.928 5.658   25.259  1   77.28  ? 178 TYR D CE2 1 
ATOM   61   C  CZ  . TYR A 1 8   ? -55.234 6.254   24.224  1   78.17  ? 178 TYR D CZ  1 
ATOM   62   O  OH  . TYR A 1 8   ? -55.171 7.612   24.142  1   80.64  ? 178 TYR D OH  1 
ATOM   63   N  N   . HIS A 1 9   ? -57.275 -0.878  24.122  1   85.09  ? 179 HIS D N   1 
ATOM   64   C  CA  . HIS A 1 9   ? -57.224 -2.32   24.382  1   90.12  ? 179 HIS D CA  1 
ATOM   65   C  C   . HIS A 1 9   ? -56.73  -3.128  23.177  1   90.82  ? 179 HIS D C   1 
ATOM   66   O  O   . HIS A 1 9   ? -56.15  -4.202  23.347  1   89.93  ? 179 HIS D O   1 
ATOM   67   C  CB  . HIS A 1 9   ? -58.552 -2.886  24.915  1   94.15  ? 179 HIS D CB  1 
ATOM   68   C  CG  . HIS A 1 9   ? -59.6   -3.191  23.886  1   108.48 ? 179 HIS D CG  1 
ATOM   69   N  ND1 . HIS A 1 9   ? -60.757 -2.447  23.749  1   121.37 ? 179 HIS D ND1 1 
ATOM   70   C  CD2 . HIS A 1 9   ? -59.697 -4.173  22.976  1   115.16 ? 179 HIS D CD2 1 
ATOM   71   C  CE1 . HIS A 1 9   ? -61.508 -2.95   22.774  1   122.43 ? 179 HIS D CE1 1 
ATOM   72   N  NE2 . HIS A 1 9   ? -60.881 -4      22.289  1   122.86 ? 179 HIS D NE2 1 
ATOM   73   N  N   . GLU A 1 10  ? -56.985 -2.635  21.962  1   90.49  ? 180 GLU D N   1 
ATOM   74   C  CA  . GLU A 1 10  ? -56.612 -3.406  20.792  1   90.18  ? 180 GLU D CA  1 
ATOM   75   C  C   . GLU A 1 10  ? -55.158 -3.17   20.415  1   84.41  ? 180 GLU D C   1 
ATOM   76   O  O   . GLU A 1 10  ? -54.436 -4.134  20.169  1   84.24  ? 180 GLU D O   1 
ATOM   77   C  CB  . GLU A 1 10  ? -57.578 -3.254  19.624  1   96.69  ? 180 GLU D CB  1 
ATOM   78   C  CG  . GLU A 1 10  ? -58.588 -4.395  19.555  1   104.54 ? 180 GLU D CG  1 
ATOM   79   C  CD  . GLU A 1 10  ? -59.687 -4.124  18.54   1   113.87 ? 180 GLU D CD  1 
ATOM   80   O  OE1 . GLU A 1 10  ? -60.654 -4.931  18.453  1   118.26 ? 180 GLU D OE1 1 
ATOM   81   O  OE2 . GLU A 1 10  ? -59.567 -3.083  17.846  1   114.21 ? 180 GLU D OE2 1 
ATOM   82   N  N   . ASP A 1 11  ? -54.759 -1.903  20.374  1   83.42  ? 181 ASP D N   1 
ATOM   83   C  CA  . ASP A 1 11  ? -53.354 -1.553  20.039  1   78.62  ? 181 ASP D CA  1 
ATOM   84   C  C   . ASP A 1 11  ? -52.431 -2.226  21.052  1   73.68  ? 181 ASP D C   1 
ATOM   85   O  O   . ASP A 1 11  ? -51.326 -2.634  20.671  1   72     ? 181 ASP D O   1 
ATOM   86   C  CB  . ASP A 1 11  ? -53.18  -0.046  20.003  1   76.74  ? 181 ASP D CB  1 
ATOM   87   C  CG  . ASP A 1 11  ? -53.838 0.66    18.83   1   81.69  ? 181 ASP D CG  1 
ATOM   88   O  OD1 . ASP A 1 11  ? -54.209 -0.032  17.861  1   85.59  ? 181 ASP D OD1 1 
ATOM   89   O  OD2 . ASP A 1 11  ? -53.984 1.895   18.903  1   80.17  ? 181 ASP D OD2 1 
ATOM   90   N  N   . ILE A 1 12  ? -52.901 -2.361  22.288  1   71.09  ? 182 ILE D N   1 
ATOM   91   C  CA  . ILE A 1 12  ? -52.059 -2.95   23.363  1   68.68  ? 182 ILE D CA  1 
ATOM   92   C  C   . ILE A 1 12  ? -51.913 -4.448  23.085  1   69.71  ? 182 ILE D C   1 
ATOM   93   O  O   . ILE A 1 12  ? -50.778 -4.945  23.146  1   70.46  ? 182 ILE D O   1 
ATOM   94   C  CB  . ILE A 1 12  ? -52.678 -2.66   24.74   1   67.66  ? 182 ILE D CB  1 
ATOM   95   C  CG1 . ILE A 1 12  ? -52.394 -1.232  25.188  1   64.71  ? 182 ILE D CG1 1 
ATOM   96   C  CG2 . ILE A 1 12  ? -52.215 -3.678  25.782  1   66.21  ? 182 ILE D CG2 1 
ATOM   97   C  CD1 . ILE A 1 12  ? -53.315 -0.741  26.288  1   64.93  ? 182 ILE D CD1 1 
ATOM   98   N  N   . HIS A 1 13  ? -53.015 -5.12   22.754  1   71.02  ? 183 HIS D N   1 
ATOM   99   C  CA  . HIS A 1 13  ? -52.973 -6.567  22.432  1   68.15  ? 183 HIS D CA  1 
ATOM   100  C  C   . HIS A 1 13  ? -51.999 -6.787  21.28   1   68.22  ? 183 HIS D C   1 
ATOM   101  O  O   . HIS A 1 13  ? -51.111 -7.641  21.384  1   70.49  ? 183 HIS D O   1 
ATOM   102  C  CB  . HIS A 1 13  ? -54.367 -7.061  22.051  1   70.67  ? 183 HIS D CB  1 
ATOM   103  C  CG  . HIS A 1 13  ? -54.433 -8.517  21.751  1   74.12  ? 183 HIS D CG  1 
ATOM   104  N  ND1 . HIS A 1 13  ? -54.676 -9.455  22.728  1   74.3   ? 183 HIS D ND1 1 
ATOM   105  C  CD2 . HIS A 1 13  ? -54.296 -9.195  20.609  1   75.2   ? 183 HIS D CD2 1 
ATOM   106  C  CE1 . HIS A 1 13  ? -54.681 -10.658 22.182  1   74.66  ? 183 HIS D CE1 1 
ATOM   107  N  NE2 . HIS A 1 13  ? -54.449 -10.524 20.896  1   76.33  ? 183 HIS D NE2 1 
ATOM   108  N  N   . THR A 1 14  ? -52.157 -6.014  20.212  1   68.62  ? 184 THR D N   1 
ATOM   109  C  CA  . THR A 1 14  ? -51.302 -6.19   19.028  1   69.62  ? 184 THR D CA  1 
ATOM   110  C  C   . THR A 1 14  ? -49.865 -5.996  19.43   1   70.64  ? 184 THR D C   1 
ATOM   111  O  O   . THR A 1 14  ? -49.016 -6.799  19.008  1   71.71  ? 184 THR D O   1 
ATOM   112  C  CB  . THR A 1 14  ? -51.738 -5.19   17.964  1   71.6   ? 184 THR D CB  1 
ATOM   113  O  OG1 . THR A 1 14  ? -53.122 -5.455  17.766  1   75.78  ? 184 THR D OG1 1 
ATOM   114  C  CG2 . THR A 1 14  ? -50.977 -5.357  16.662  1   71.13  ? 184 THR D CG2 1 
ATOM   115  N  N   . TYR A 1 15  ? -49.589 -4.996  20.258  1   69.86  ? 185 TYR D N   1 
ATOM   116  C  CA  . TYR A 1 15  ? -48.191 -4.7    20.657  1   65.3   ? 185 TYR D CA  1 
ATOM   117  C  C   . TYR A 1 15  ? -47.657 -5.878  21.437  1   63.6   ? 185 TYR D C   1 
ATOM   118  O  O   . TYR A 1 15  ? -46.549 -6.342  21.149  1   62.34  ? 185 TYR D O   1 
ATOM   119  C  CB  . TYR A 1 15  ? -48.151 -3.417  21.49   1   62.86  ? 185 TYR D CB  1 
ATOM   120  C  CG  . TYR A 1 15  ? -46.741 -2.978  21.847  1   64.27  ? 185 TYR D CG  1 
ATOM   121  C  CD1 . TYR A 1 15  ? -45.784 -2.801  20.858  1   66.57  ? 185 TYR D CD1 1 
ATOM   122  C  CD2 . TYR A 1 15  ? -46.366 -2.766  23.166  1   61.29  ? 185 TYR D CD2 1 
ATOM   123  C  CE1 . TYR A 1 15  ? -44.495 -2.409  21.168  1   62.14  ? 185 TYR D CE1 1 
ATOM   124  C  CE2 . TYR A 1 15  ? -45.079 -2.376  23.489  1   59.9   ? 185 TYR D CE2 1 
ATOM   125  C  CZ  . TYR A 1 15  ? -44.144 -2.197  22.487  1   62.18  ? 185 TYR D CZ  1 
ATOM   126  O  OH  . TYR A 1 15  ? -42.872 -1.816  22.78   1   61.54  ? 185 TYR D OH  1 
ATOM   127  N  N   . LEU A 1 16  ? -48.437 -6.356  22.399  1   62.04  ? 186 LEU D N   1 
ATOM   128  C  CA  . LEU A 1 16  ? -47.991 -7.474  23.26   1   61.24  ? 186 LEU D CA  1 
ATOM   129  C  C   . LEU A 1 16  ? -47.657 -8.686  22.389  1   63.63  ? 186 LEU D C   1 
ATOM   130  O  O   . LEU A 1 16  ? -46.629 -9.333  22.632  1   61.51  ? 186 LEU D O   1 
ATOM   131  C  CB  . LEU A 1 16  ? -49.117 -7.768  24.242  1   60.12  ? 186 LEU D CB  1 
ATOM   132  C  CG  . LEU A 1 16  ? -49.343 -6.732  25.345  1   59.13  ? 186 LEU D CG  1 
ATOM   133  C  CD1 . LEU A 1 16  ? -50.256 -7.323  26.397  1   59.66  ? 186 LEU D CD1 1 
ATOM   134  C  CD2 . LEU A 1 16  ? -48.033 -6.27   25.955  1   57.19  ? 186 LEU D CD2 1 
ATOM   135  N  N   . ARG A 1 17  ? -48.496 -8.963  21.399  1   65.28  ? 187 ARG D N   1 
ATOM   136  C  CA  . ARG A 1 17  ? -48.266 -10.112 20.498  1   65.83  ? 187 ARG D CA  1 
ATOM   137  C  C   . ARG A 1 17  ? -46.925 -9.929  19.783  1   67.06  ? 187 ARG D C   1 
ATOM   138  O  O   . ARG A 1 17  ? -46.171 -10.905 19.672  1   69.6   ? 187 ARG D O   1 
ATOM   139  C  CB  . ARG A 1 17  ? -49.426 -10.206 19.505  1   65.56  ? 187 ARG D CB  1 
ATOM   140  C  CG  . ARG A 1 17  ? -50.756 -10.575 20.143  1   66.3   ? 187 ARG D CG  1 
ATOM   141  C  CD  . ARG A 1 17  ? -50.825 -12.05  20.482  1   64.55  ? 187 ARG D CD  1 
ATOM   142  N  NE  . ARG A 1 17  ? -50.693 -12.884 19.284  1   64.88  ? 187 ARG D NE  1 
ATOM   143  C  CZ  . ARG A 1 17  ? -51.705 -13.216 18.498  1   67.32  ? 187 ARG D CZ  1 
ATOM   144  N  NH1 . ARG A 1 17  ? -52.917 -13.349 19.005  1   68.12  ? 187 ARG D NH1 1 
ATOM   145  N  NH2 . ARG A 1 17  ? -51.501 -13.421 17.211  1   67.03  ? 187 ARG D NH2 1 
ATOM   146  N  N   . GLU A 1 18  ? -46.656 -8.719  19.31   1   66.78  ? 188 GLU D N   1 
ATOM   147  C  CA  . GLU A 1 18  ? -45.399 -8.462  18.574  1   64.98  ? 188 GLU D CA  1 
ATOM   148  C  C   . GLU A 1 18  ? -44.243 -8.578  19.565  1   63.35  ? 188 GLU D C   1 
ATOM   149  O  O   . GLU A 1 18  ? -43.171 -9.058  19.168  1   63.32  ? 188 GLU D O   1 
ATOM   150  C  CB  . GLU A 1 18  ? -45.533 -7.097  17.902  1   69.44  ? 188 GLU D CB  1 
ATOM   151  C  CG  . GLU A 1 18  ? -44.349 -6.692  17.033  1   76.53  ? 188 GLU D CG  1 
ATOM   152  C  CD  . GLU A 1 18  ? -44.59  -5.351  16.37   1   82.95  ? 188 GLU D CD  1 
ATOM   153  O  OE1 . GLU A 1 18  ? -45.648 -4.745  16.625  1   85.11  ? 188 GLU D OE1 1 
ATOM   154  O  OE2 . GLU A 1 18  ? -43.713 -4.912  15.599  1   77.27  ? 188 GLU D OE2 1 
ATOM   155  N  N   . MET A 1 19  ? -44.483 -8.209  20.822  1   63.27  ? 189 MET D N   1 
ATOM   156  C  CA  . MET A 1 19  ? -43.384 -8.196  21.778  1   64.23  ? 189 MET D CA  1 
ATOM   157  C  C   . MET A 1 19  ? -43.131 -9.565  22.402  1   65.58  ? 189 MET D C   1 
ATOM   158  O  O   . MET A 1 19  ? -42.008 -9.801  22.834  1   64.56  ? 189 MET D O   1 
ATOM   159  C  CB  . MET A 1 19  ? -43.654 -7.234  22.932  1   63.19  ? 189 MET D CB  1 
ATOM   160  C  CG  . MET A 1 19  ? -43.778 -5.809  22.482  1   69.02  ? 189 MET D CG  1 
ATOM   161  S  SD  . MET A 1 19  ? -42.175 -5.209  21.937  1   73.17  ? 189 MET D SD  1 
ATOM   162  C  CE  . MET A 1 19  ? -41.249 -5.349  23.488  1   71.54  ? 189 MET D CE  1 
ATOM   163  N  N   . GLU A 1 20  ? -44.163 -10.406 22.488  1   65.13  ? 190 GLU D N   1 
ATOM   164  C  CA  . GLU A 1 20  ? -44.024 -11.751 23.102  1   64.31  ? 190 GLU D CA  1 
ATOM   165  C  C   . GLU A 1 20  ? -43.127 -12.614 22.215  1   62.63  ? 190 GLU D C   1 
ATOM   166  O  O   . GLU A 1 20  ? -42.61  -13.631 22.701  1   62.93  ? 190 GLU D O   1 
ATOM   167  C  CB  . GLU A 1 20  ? -45.385 -12.416 23.296  1   65.41  ? 190 GLU D CB  1 
ATOM   168  C  CG  . GLU A 1 20  ? -45.893 -13.167 22.071  1   65.63  ? 190 GLU D CG  1 
ATOM   169  C  CD  . GLU A 1 20  ? -47.273 -13.753 22.279  1   68.08  ? 190 GLU D CD  1 
ATOM   170  O  OE1 . GLU A 1 20  ? -47.56  -14.181 23.41   1   66.05  ? 190 GLU D OE1 1 
ATOM   171  O  OE2 . GLU A 1 20  ? -48.055 -13.781 21.312  1   68.93  ? 190 GLU D OE2 1 
ATOM   172  N  N   . VAL A 1 21  ? -42.941 -12.195 20.972  1   61.6   ? 191 VAL D N   1 
ATOM   173  C  CA  . VAL A 1 21  ? -42.073 -12.947 20.031  1   62.56  ? 191 VAL D CA  1 
ATOM   174  C  C   . VAL A 1 21  ? -40.628 -12.512 20.276  1   63.46  ? 191 VAL D C   1 
ATOM   175  O  O   . VAL A 1 21  ? -39.739 -13.375 20.254  1   65.61  ? 191 VAL D O   1 
ATOM   176  C  CB  . VAL A 1 21  ? -42.541 -12.651 18.595  1   61.62  ? 191 VAL D CB  1 
ATOM   177  C  CG1 . VAL A 1 21  ? -41.504 -13.032 17.548  1   59.45  ? 191 VAL D CG1 1 
ATOM   178  C  CG2 . VAL A 1 21  ? -43.881 -13.307 18.295  1   58.91  ? 191 VAL D CG2 1 
ATOM   179  N  N   . LYS A 1 22  ? -40.506 -11.134 20.548  1   66.44  ? 192 LYS D N   1 
ATOM   180  C  CA  . LYS A 1 22  ? -39.153 -10.566 20.759  1   70.42  ? 192 LYS D CA  1 
ATOM   181  C  C   . LYS A 1 22  ? -38.599 -11.062 22.099  1   67.59  ? 192 LYS D C   1 
ATOM   182  O  O   . LYS A 1 22  ? -37.382 -11.294 22.186  1   68.57  ? 192 LYS D O   1 
ATOM   183  C  CB  . LYS A 1 22  ? -39.237 -9.041  20.705  1   78.43  ? 192 LYS D CB  1 
ATOM   184  C  CG  . LYS A 1 22  ? -37.926 -8.277  20.831  1   91.75  ? 192 LYS D CG  1 
ATOM   185  C  CD  . LYS A 1 22  ? -38.097 -6.767  20.718  1   96.83  ? 192 LYS D CD  1 
ATOM   186  C  CE  . LYS A 1 22  ? -36.804 -6.036  20.868  1   102.79 ? 192 LYS D CE  1 
ATOM   187  N  NZ  . LYS A 1 22  ? -36.998 -4.588  20.755  1   100.19 ? 192 LYS D NZ  1 
ATOM   188  N  N   . CYS A 1 23  ? -39.47  -11.255 23.085  1   65.15  ? 193 CYS D N   1 
ATOM   189  C  CA  . CYS A 1 23  ? -39.019 -11.657 24.438  1   60.32  ? 193 CYS D CA  1 
ATOM   190  C  C   . CYS A 1 23  ? -39.144 -13.174 24.586  1   61.15  ? 193 CYS D C   1 
ATOM   191  O  O   . CYS A 1 23  ? -39.285 -13.641 25.724  1   63.88  ? 193 CYS D O   1 
ATOM   192  C  CB  . CYS A 1 23  ? -39.846 -10.945 25.5    1   59.13  ? 193 CYS D CB  1 
ATOM   193  S  SG  . CYS A 1 23  ? -39.744 -9.139  25.418  1   69.97  ? 193 CYS D SG  1 
ATOM   194  N  N   . LYS A 1 24  ? -39.074 -13.902 23.477  1   63.11  ? 194 LYS D N   1 
ATOM   195  C  CA  . LYS A 1 24  ? -39.269 -15.371 23.526  1   64.19  ? 194 LYS D CA  1 
ATOM   196  C  C   . LYS A 1 24  ? -37.938 -16.069 23.792  1   64.48  ? 194 LYS D C   1 
ATOM   197  O  O   . LYS A 1 24  ? -36.956 -15.763 23.1    1   65.05  ? 194 LYS D O   1 
ATOM   198  C  CB  . LYS A 1 24  ? -39.856 -15.941 22.233  1   63.52  ? 194 LYS D CB  1 
ATOM   199  C  CG  . LYS A 1 24  ? -40.137 -17.431 22.272  1   66.01  ? 194 LYS D CG  1 
ATOM   200  C  CD  . LYS A 1 24  ? -40.765 -17.977 20.997  1   78.2   ? 194 LYS D CD  1 
ATOM   201  C  CE  . LYS A 1 24  ? -40.998 -19.452 21.079  1   79.9   ? 194 LYS D CE  1 
ATOM   202  N  NZ  . LYS A 1 24  ? -41.602 -19.99  19.858  1   75.72  ? 194 LYS D NZ  1 
ATOM   203  N  N   . PRO A 1 25  ? -37.878 -16.984 24.775  1   64.3   ? 195 PRO D N   1 
ATOM   204  C  CA  . PRO A 1 25  ? -36.671 -17.753 25.015  1   58.39  ? 195 PRO D CA  1 
ATOM   205  C  C   . PRO A 1 25  ? -36.353 -18.695 23.876  1   59.76  ? 195 PRO D C   1 
ATOM   206  O  O   . PRO A 1 25  ? -37.255 -19.016 23.09   1   60.56  ? 195 PRO D O   1 
ATOM   207  C  CB  . PRO A 1 25  ? -37.083 -18.503 26.269  1   58.39  ? 195 PRO D CB  1 
ATOM   208  C  CG  . PRO A 1 25  ? -38.113 -17.614 26.908  1   59.06  ? 195 PRO D CG  1 
ATOM   209  C  CD  . PRO A 1 25  ? -38.947 -17.249 25.712  1   62.33  ? 195 PRO D CD  1 
ATOM   210  N  N   . LYS A 1 26  ? -35.097 -19.138 23.788  1   60.77  ? 196 LYS D N   1 
ATOM   211  C  CA  . LYS A 1 26  ? -34.694 -20.117 22.746  1   63.68  ? 196 LYS D CA  1 
ATOM   212  C  C   . LYS A 1 26  ? -35.319 -21.471 23.085  1   63.49  ? 196 LYS D C   1 
ATOM   213  O  O   . LYS A 1 26  ? -34.99  -22.025 24.142  1   62.66  ? 196 LYS D O   1 
ATOM   214  C  CB  . LYS A 1 26  ? -33.176 -20.257 22.617  1   66.47  ? 196 LYS D CB  1 
ATOM   215  C  CG  . LYS A 1 26  ? -32.456 -19.043 22.061  1   73.86  ? 196 LYS D CG  1 
ATOM   216  C  CD  . LYS A 1 26  ? -32.773 -18.774 20.597  1   89.25  ? 196 LYS D CD  1 
ATOM   217  C  CE  . LYS A 1 26  ? -31.585 -18.252 19.856  1   97.24  ? 196 LYS D CE  1 
ATOM   218  N  NZ  . LYS A 1 26  ? -31.53  -16.789 19.886  1   94.53  ? 196 LYS D NZ  1 
ATOM   219  N  N   . VAL A 1 27  ? -36.166 -21.984 22.2    1   64.05  ? 197 VAL D N   1 
ATOM   220  C  CA  . VAL A 1 27  ? -36.9   -23.251 22.475  1   65.82  ? 197 VAL D CA  1 
ATOM   221  C  C   . VAL A 1 27  ? -35.919 -24.379 22.798  1   62.3   ? 197 VAL D C   1 
ATOM   222  O  O   . VAL A 1 27  ? -36.26  -25.227 23.637  1   62.19  ? 197 VAL D O   1 
ATOM   223  C  CB  . VAL A 1 27  ? -37.79  -23.598 21.269  1   66.73  ? 197 VAL D CB  1 
ATOM   224  C  CG1 . VAL A 1 27  ? -38.401 -24.988 21.378  1   72.79  ? 197 VAL D CG1 1 
ATOM   225  C  CG2 . VAL A 1 27  ? -38.874 -22.552 21.056  1   67.82  ? 197 VAL D CG2 1 
ATOM   226  N  N   . GLY A 1 28  ? -34.731 -24.37  22.202  1   62.07  ? 198 GLY D N   1 
ATOM   227  C  CA  . GLY A 1 28  ? -33.897 -25.527 22.467  1   70.66  ? 198 GLY D CA  1 
ATOM   228  C  C   . GLY A 1 28  ? -32.842 -25.308 23.554  1   70.13  ? 198 GLY D C   1 
ATOM   229  O  O   . GLY A 1 28  ? -31.933 -26.116 23.671  1   77.93  ? 198 GLY D O   1 
ATOM   230  N  N   . TYR A 1 29  ? -32.966 -24.272 24.387  1   62.81  ? 199 TYR D N   1 
ATOM   231  C  CA  . TYR A 1 29  ? -31.782 -23.779 25.082  1   57.23  ? 199 TYR D CA  1 
ATOM   232  C  C   . TYR A 1 29  ? -31.189 -24.835 26.011  1   57.05  ? 199 TYR D C   1 
ATOM   233  O  O   . TYR A 1 29  ? -29.979 -24.877 26.195  1   57.77  ? 199 TYR D O   1 
ATOM   234  C  CB  . TYR A 1 29  ? -31.961 -22.421 25.766  1   51.32  ? 199 TYR D CB  1 
ATOM   235  C  CG  . TYR A 1 29  ? -32.672 -22.408 27.114  1   50.11  ? 199 TYR D CG  1 
ATOM   236  C  CD1 . TYR A 1 29  ? -32.056 -22.898 28.262  1   49.87  ? 199 TYR D CD1 1 
ATOM   237  C  CD2 . TYR A 1 29  ? -33.93  -21.83  27.263  1   48.79  ? 199 TYR D CD2 1 
ATOM   238  C  CE1 . TYR A 1 29  ? -32.679 -22.844 29.501  1   49.6   ? 199 TYR D CE1 1 
ATOM   239  C  CE2 . TYR A 1 29  ? -34.565 -21.775 28.492  1   48.22  ? 199 TYR D CE2 1 
ATOM   240  C  CZ  . TYR A 1 29  ? -33.937 -22.276 29.616  1   50.91  ? 199 TYR D CZ  1 
ATOM   241  O  OH  . TYR A 1 29  ? -34.583 -22.203 30.819  1   54     ? 199 TYR D OH  1 
ATOM   242  N  N   . MET A 1 30  ? -32.023 -25.707 26.575  1   57.5   ? 200 MET D N   1 
ATOM   243  C  CA  . MET A 1 30  ? -31.533 -26.592 27.62   1   60.24  ? 200 MET D CA  1 
ATOM   244  C  C   . MET A 1 30  ? -30.546 -27.658 27.096  1   65.57  ? 200 MET D C   1 
ATOM   245  O  O   . MET A 1 30  ? -29.67  -28.149 27.833  1   63.62  ? 200 MET D O   1 
ATOM   246  C  CB  . MET A 1 30  ? -32.719 -27.181 28.391  1   61.14  ? 200 MET D CB  1 
ATOM   247  C  CG  . MET A 1 30  ? -32.311 -27.702 29.754  1   64.65  ? 200 MET D CG  1 
ATOM   248  S  SD  . MET A 1 30  ? -31.793 -26.343 30.819  1   68     ? 200 MET D SD  1 
ATOM   249  C  CE  . MET A 1 30  ? -33.442 -25.899 31.367  1   65.1   ? 200 MET D CE  1 
ATOM   250  N  N   . LYS A 1 31  ? -30.706 -28.078 25.831  1   69     ? 201 LYS D N   1 
ATOM   251  C  CA  . LYS A 1 31  ? -29.79  -29.055 25.268  1   71.85  ? 201 LYS D CA  1 
ATOM   252  C  C   . LYS A 1 31  ? -28.415 -28.43  25.048  1   68.62  ? 201 LYS D C   1 
ATOM   253  O  O   . LYS A 1 31  ? -27.45  -29.164 24.839  1   70.34  ? 201 LYS D O   1 
ATOM   254  C  CB  . LYS A 1 31  ? -30.244 -29.619 23.921  1   82.2   ? 201 LYS D CB  1 
ATOM   255  C  CG  . LYS A 1 31  ? -31.483 -30.484 23.907  1   96.64  ? 201 LYS D CG  1 
ATOM   256  C  CD  . LYS A 1 31  ? -31.984 -30.735 22.486  1   103.69 ? 201 LYS D CD  1 
ATOM   257  C  CE  . LYS A 1 31  ? -32.625 -29.524 21.863  1   99.76  ? 201 LYS D CE  1 
ATOM   258  N  NZ  . LYS A 1 31  ? -33.116 -29.872 20.53   1   106.43 ? 201 LYS D NZ  1 
ATOM   259  N  N   . LYS A 1 32  ? -28.337 -27.089 25.057  1   64.17  ? 202 LYS D N   1 
ATOM   260  C  CA  . LYS A 1 32  ? -27.079 -26.381 24.865  1   65.18  ? 202 LYS D CA  1 
ATOM   261  C  C   . LYS A 1 32  ? -26.446 -25.958 26.193  1   62.59  ? 202 LYS D C   1 
ATOM   262  O  O   . LYS A 1 32  ? -25.341 -25.424 26.188  1   61.1   ? 202 LYS D O   1 
ATOM   263  C  CB  . LYS A 1 32  ? -27.32  -25.191 23.939  1   69.79  ? 202 LYS D CB  1 
ATOM   264  C  CG  . LYS A 1 32  ? -27.412 -25.585 22.479  1   78.13  ? 202 LYS D CG  1 
ATOM   265  C  CD  . LYS A 1 32  ? -28.356 -24.664 21.721  1   84.83  ? 202 LYS D CD  1 
ATOM   266  C  CE  . LYS A 1 32  ? -28.311 -24.901 20.232  1   98.99  ? 202 LYS D CE  1 
ATOM   267  N  NZ  . LYS A 1 32  ? -29.324 -24.087 19.551  1   106.94 ? 202 LYS D NZ  1 
ATOM   268  N  N   . GLN A 1 33  ? -27.162 -26.181 27.311  1   60.73  ? 203 GLN D N   1 
ATOM   269  C  CA  . GLN A 1 33  ? -26.637 -26.049 28.663  1   55.26  ? 203 GLN D CA  1 
ATOM   270  C  C   . GLN A 1 33  ? -26.007 -27.377 29.083  1   57.16  ? 203 GLN D C   1 
ATOM   271  O  O   . GLN A 1 33  ? -26.719 -28.345 29.371  1   58.35  ? 203 GLN D O   1 
ATOM   272  C  CB  . GLN A 1 33  ? -27.753 -25.714 29.653  1   53.01  ? 203 GLN D CB  1 
ATOM   273  C  CG  . GLN A 1 33  ? -28.38  -24.34  29.48   1   50.39  ? 203 GLN D CG  1 
ATOM   274  C  CD  . GLN A 1 33  ? -27.47  -23.215 29.934  1   50.17  ? 203 GLN D CD  1 
ATOM   275  O  OE1 . GLN A 1 33  ? -26.464 -23.436 30.62   1   48.1   ? 203 GLN D OE1 1 
ATOM   276  N  NE2 . GLN A 1 33  ? -27.816 -21.992 29.546  1   47.18  ? 203 GLN D NE2 1 
ATOM   277  N  N   . PRO A 1 34  ? -24.655 -27.458 29.134  1   59.46  ? 204 PRO D N   1 
ATOM   278  C  CA  . PRO A 1 34  ? -23.964 -28.729 29.37   1   60.19  ? 204 PRO D CA  1 
ATOM   279  C  C   . PRO A 1 34  ? -24.154 -29.231 30.802  1   60.72  ? 204 PRO D C   1 
ATOM   280  O  O   . PRO A 1 34  ? -24.068 -30.436 31.055  1   63.75  ? 204 PRO D O   1 
ATOM   281  C  CB  . PRO A 1 34  ? -22.472 -28.441 29.016  1   59.43  ? 204 PRO D CB  1 
ATOM   282  C  CG  . PRO A 1 34  ? -22.32  -26.929 29.106  1   59.87  ? 204 PRO D CG  1 
ATOM   283  C  CD  . PRO A 1 34  ? -23.719 -26.322 28.986  1   59.88  ? 204 PRO D CD  1 
ATOM   284  N  N   . ASP A 1 35  ? -24.454 -28.294 31.713  1   59.47  ? 205 ASP D N   1 
ATOM   285  C  CA  . ASP A 1 35  ? -24.427 -28.602 33.127  1   59.81  ? 205 ASP D CA  1 
ATOM   286  C  C   . ASP A 1 35  ? -25.811 -28.506 33.77   1   58.62  ? 205 ASP D C   1 
ATOM   287  O  O   . ASP A 1 35  ? -25.938 -28.926 34.912  1   60.43  ? 205 ASP D O   1 
ATOM   288  C  CB  . ASP A 1 35  ? -23.362 -27.808 33.862  1   62.99  ? 205 ASP D CB  1 
ATOM   289  C  CG  . ASP A 1 35  ? -23.024 -28.319 35.256  1   68.32  ? 205 ASP D CG  1 
ATOM   290  O  OD1 . ASP A 1 35  ? -22.577 -29.476 35.324  1   78.08  ? 205 ASP D OD1 1 
ATOM   291  O  OD2 . ASP A 1 35  ? -23.207 -27.572 36.262  1   67.43  ? 205 ASP D OD2 1 
ATOM   292  N  N   . ILE A 1 36  ? -26.84  -27.972 33.084  1   55.55  ? 206 ILE D N   1 
ATOM   293  C  CA  . ILE A 1 36  ? -28.174 -27.944 33.683  1   55.89  ? 206 ILE D CA  1 
ATOM   294  C  C   . ILE A 1 36  ? -29.248 -28.56  32.775  1   58.99  ? 206 ILE D C   1 
ATOM   295  O  O   . ILE A 1 36  ? -29.033 -28.792 31.579  1   62.62  ? 206 ILE D O   1 
ATOM   296  C  CB  . ILE A 1 36  ? -28.559 -26.549 34.202  1   56.85  ? 206 ILE D CB  1 
ATOM   297  C  CG1 . ILE A 1 36  ? -28.454 -25.514 33.133  1   54.75  ? 206 ILE D CG1 1 
ATOM   298  C  CG2 . ILE A 1 36  ? -27.737 -26.149 35.439  1   58.6   ? 206 ILE D CG2 1 
ATOM   299  C  CD1 . ILE A 1 36  ? -28.799 -24.141 33.649  1   57.43  ? 206 ILE D CD1 1 
ATOM   300  N  N   . THR A 1 37  ? -30.403 -28.885 33.383  1   57.56  ? 207 THR D N   1 
ATOM   301  C  CA  . THR A 1 37  ? -31.427 -29.728 32.769  1   59.74  ? 207 THR D CA  1 
ATOM   302  C  C   . THR A 1 37  ? -32.812 -29.165 33.069  1   62.94  ? 207 THR D C   1 
ATOM   303  O  O   . THR A 1 37  ? -32.996 -28.44  34.049  1   64.01  ? 207 THR D O   1 
ATOM   304  C  CB  . THR A 1 37  ? -31.364 -31.191 33.233  1   57.73  ? 207 THR D CB  1 
ATOM   305  O  OG1 . THR A 1 37  ? -31.759 -31.306 34.599  1   57.78  ? 207 THR D OG1 1 
ATOM   306  C  CG2 . THR A 1 37  ? -30.007 -31.839 33.03   1   54.95  ? 207 THR D CG2 1 
ATOM   307  N  N   . ASN A 1 38  ? -33.787 -29.59  32.256  1   66.93  ? 208 ASN D N   1 
ATOM   308  C  CA  . ASN A 1 38  ? -35.189 -29.21  32.397  1   66.63  ? 208 ASN D CA  1 
ATOM   309  C  C   . ASN A 1 38  ? -35.685 -29.415 33.833  1   61.3   ? 208 ASN D C   1 
ATOM   310  O  O   . ASN A 1 38  ? -36.502 -28.631 34.322  1   57.46  ? 208 ASN D O   1 
ATOM   311  C  CB  . ASN A 1 38  ? -36.045 -29.937 31.364  1   68.8   ? 208 ASN D CB  1 
ATOM   312  C  CG  . ASN A 1 38  ? -35.923 -29.372 29.964  1   70.86  ? 208 ASN D CG  1 
ATOM   313  O  OD1 . ASN A 1 38  ? -35.641 -28.179 29.774  1   67.48  ? 208 ASN D OD1 1 
ATOM   314  N  ND2 . ASN A 1 38  ? -36.18  -30.215 28.97   1   75.72  ? 208 ASN D ND2 1 
ATOM   315  N  N   . SER A 1 39  ? -35.19  -30.489 34.47   1   60.6   ? 209 SER D N   1 
ATOM   316  C  CA  . SER A 1 39  ? -35.574 -30.939 35.802  1   60.99  ? 209 SER D CA  1 
ATOM   317  C  C   . SER A 1 39  ? -35.082 -29.964 36.876  1   61.54  ? 209 SER D C   1 
ATOM   318  O  O   . SER A 1 39  ? -35.754 -29.733 37.893  1   58.91  ? 209 SER D O   1 
ATOM   319  C  CB  . SER A 1 39  ? -35.026 -32.311 36.052  1   61.19  ? 209 SER D CB  1 
ATOM   320  O  OG  . SER A 1 39  ? -35.007 -32.582 37.439  1   61.84  ? 209 SER D OG  1 
ATOM   321  N  N   . MET A 1 40  ? -33.867 -29.433 36.67   1   60.37  ? 210 MET D N   1 
ATOM   322  C  CA  . MET A 1 40  ? -33.288 -28.487 37.613  1   58.83  ? 210 MET D CA  1 
ATOM   323  C  C   . MET A 1 40  ? -34.076 -27.185 37.534  1   57.79  ? 210 MET D C   1 
ATOM   324  O  O   . MET A 1 40  ? -34.393 -26.589 38.56   1   58.12  ? 210 MET D O   1 
ATOM   325  C  CB  . MET A 1 40  ? -31.81  -28.236 37.306  1   57.53  ? 210 MET D CB  1 
ATOM   326  C  CG  . MET A 1 40  ? -30.945 -29.453 37.506  1   57.41  ? 210 MET D CG  1 
ATOM   327  S  SD  . MET A 1 40  ? -29.246 -29.057 37.073  1   60.2   ? 210 MET D SD  1 
ATOM   328  C  CE  . MET A 1 40  ? -28.524 -30.706 36.982  1   54.33  ? 210 MET D CE  1 
ATOM   329  N  N   . ARG A 1 41  ? -34.428 -26.799 36.303  1   54.28  ? 211 ARG D N   1 
ATOM   330  C  CA  . ARG A 1 41  ? -35.243 -25.626 36.071  1   52.97  ? 211 ARG D CA  1 
ATOM   331  C  C   . ARG A 1 41  ? -36.59  -25.804 36.765  1   52.58  ? 211 ARG D C   1 
ATOM   332  O  O   . ARG A 1 41  ? -37.136 -24.851 37.293  1   53.99  ? 211 ARG D O   1 
ATOM   333  C  CB  . ARG A 1 41  ? -35.305 -25.335 34.564  1   51.43  ? 211 ARG D CB  1 
ATOM   334  C  CG  . ARG A 1 41  ? -36.112 -24.098 34.197  1   49.65  ? 211 ARG D CG  1 
ATOM   335  C  CD  . ARG A 1 41  ? -36.522 -24.17  32.726  1   53.15  ? 211 ARG D CD  1 
ATOM   336  N  NE  . ARG A 1 41  ? -37.469 -23.123 32.336  1   51.12  ? 211 ARG D NE  1 
ATOM   337  C  CZ  . ARG A 1 41  ? -38.733 -23.035 32.733  1   50.38  ? 211 ARG D CZ  1 
ATOM   338  N  NH1 . ARG A 1 41  ? -39.334 -24.035 33.354  1   49.99  ? 211 ARG D NH1 1 
ATOM   339  N  NH2 . ARG A 1 41  ? -39.398 -21.926 32.488  1   49.76  ? 211 ARG D NH2 1 
ATOM   340  N  N   . ALA A 1 42  ? -37.122 -27.025 36.773  1   56.08  ? 212 ALA D N   1 
ATOM   341  C  CA  . ALA A 1 42  ? -38.375 -27.311 37.462  1   57.66  ? 212 ALA D CA  1 
ATOM   342  C  C   . ALA A 1 42  ? -38.269 -26.92  38.937  1   56.9   ? 212 ALA D C   1 
ATOM   343  O  O   . ALA A 1 42  ? -39.095 -26.156 39.431  1   56.9   ? 212 ALA D O   1 
ATOM   344  C  CB  . ALA A 1 42  ? -38.781 -28.763 37.283  1   56.48  ? 212 ALA D CB  1 
ATOM   345  N  N   . ILE A 1 43  ? -37.24  -27.428 39.625  1   56.67  ? 213 ILE D N   1 
ATOM   346  C  CA  . ILE A 1 43  ? -36.997 -27.084 41.021  1   55.91  ? 213 ILE D CA  1 
ATOM   347  C  C   . ILE A 1 43  ? -36.893 -25.574 41.205  1   55.11  ? 213 ILE D C   1 
ATOM   348  O  O   . ILE A 1 43  ? -37.317 -25.043 42.217  1   56.79  ? 213 ILE D O   1 
ATOM   349  C  CB  . ILE A 1 43  ? -35.723 -27.778 41.523  1   55.75  ? 213 ILE D CB  1 
ATOM   350  C  CG1 . ILE A 1 43  ? -35.945 -29.282 41.653  1   57.13  ? 213 ILE D CG1 1 
ATOM   351  C  CG2 . ILE A 1 43  ? -35.225 -27.153 42.83   1   54.69  ? 213 ILE D CG2 1 
ATOM   352  C  CD1 . ILE A 1 43  ? -34.68  -30.083 41.44   1   57.24  ? 213 ILE D CD1 1 
ATOM   353  N  N   . LEU A 1 44  ? -36.28  -24.888 40.242  1   56.1   ? 214 LEU D N   1 
ATOM   354  C  CA  . LEU A 1 44  ? -36.007 -23.476 40.405  1   53.88  ? 214 LEU D CA  1 
ATOM   355  C  C   . LEU A 1 44  ? -37.33  -22.727 40.392  1   56.72  ? 214 LEU D C   1 
ATOM   356  O  O   . LEU A 1 44  ? -37.598 -21.921 41.29   1   62.05  ? 214 LEU D O   1 
ATOM   357  C  CB  . LEU A 1 44  ? -35.057 -22.977 39.326  1   50.3   ? 214 LEU D CB  1 
ATOM   358  C  CG  . LEU A 1 44  ? -34.823 -21.466 39.352  1   51.05  ? 214 LEU D CG  1 
ATOM   359  C  CD1 . LEU A 1 44  ? -34.175 -21.045 40.653  1   50.86  ? 214 LEU D CD1 1 
ATOM   360  C  CD2 . LEU A 1 44  ? -33.986 -21.015 38.166  1   50.31  ? 214 LEU D CD2 1 
ATOM   361  N  N   . VAL A 1 45  ? -38.151 -23.028 39.379  1   54.56  ? 215 VAL D N   1 
ATOM   362  C  CA  . VAL A 1 45  ? -39.425 -22.342 39.218  1   53.97  ? 215 VAL D CA  1 
ATOM   363  C  C   . VAL A 1 45  ? -40.333 -22.647 40.41   1   54.23  ? 215 VAL D C   1 
ATOM   364  O  O   . VAL A 1 45  ? -41.017 -21.763 40.926  1   54.16  ? 215 VAL D O   1 
ATOM   365  C  CB  . VAL A 1 45  ? -40.08  -22.608 37.852  1   51.67  ? 215 VAL D CB  1 
ATOM   366  C  CG1 . VAL A 1 45  ? -41.4   -21.864 37.705  1   51.77  ? 215 VAL D CG1 1 
ATOM   367  C  CG2 . VAL A 1 45  ? -39.131 -22.187 36.74   1   48.49  ? 215 VAL D CG2 1 
ATOM   368  N  N   . ASP A 1 46  ? -40.284 -23.892 40.876  1   55.04  ? 216 ASP D N   1 
ATOM   369  C  CA  . ASP A 1 46  ? -41.133 -24.297 41.976  1   58.03  ? 216 ASP D CA  1 
ATOM   370  C  C   . ASP A 1 46  ? -40.76  -23.507 43.223  1   59.87  ? 216 ASP D C   1 
ATOM   371  O  O   . ASP A 1 46  ? -41.62  -23.122 44.02   1   61.98  ? 216 ASP D O   1 
ATOM   372  C  CB  . ASP A 1 46  ? -41.018 -25.784 42.216  1   57.88  ? 216 ASP D CB  1 
ATOM   373  C  CG  . ASP A 1 46  ? -41.969 -26.258 43.29   1   61.32  ? 216 ASP D CG  1 
ATOM   374  O  OD1 . ASP A 1 46  ? -41.62  -26.086 44.472  1   62.19  ? 216 ASP D OD1 1 
ATOM   375  O  OD2 . ASP A 1 46  ? -43.075 -26.713 42.929  1   62.72  ? 216 ASP D OD2 1 
ATOM   376  N  N   . TRP A 1 47  ? -39.455 -23.282 43.374  1   59.46  ? 217 TRP D N   1 
ATOM   377  C  CA  . TRP A 1 47  ? -38.954 -22.556 44.524  1   60.69  ? 217 TRP D CA  1 
ATOM   378  C  C   . TRP A 1 47  ? -39.377 -21.085 44.444  1   61.4   ? 217 TRP D C   1 
ATOM   379  O  O   . TRP A 1 47  ? -39.778 -20.494 45.453  1   59.32  ? 217 TRP D O   1 
ATOM   380  C  CB  . TRP A 1 47  ? -37.441 -22.749 44.66   1   57.16  ? 217 TRP D CB  1 
ATOM   381  C  CG  . TRP A 1 47  ? -36.827 -21.855 45.703  1   57.5   ? 217 TRP D CG  1 
ATOM   382  C  CD1 . TRP A 1 47  ? -36.945 -21.996 47.053  1   57.49  ? 217 TRP D CD1 1 
ATOM   383  C  CD2 . TRP A 1 47  ? -35.98  -20.706 45.475  1   55.28  ? 217 TRP D CD2 1 
ATOM   384  N  NE1 . TRP A 1 47  ? -36.247 -21.007 47.681  1   57.83  ? 217 TRP D NE1 1 
ATOM   385  C  CE2 . TRP A 1 47  ? -35.633 -20.208 46.746  1   56.76  ? 217 TRP D CE2 1 
ATOM   386  C  CE3 . TRP A 1 47  ? -35.471 -20.064 44.336  1   53.72  ? 217 TRP D CE3 1 
ATOM   387  C  CZ2 . TRP A 1 47  ? -34.806 -19.09  46.907  1   56.47  ? 217 TRP D CZ2 1 
ATOM   388  C  CZ3 . TRP A 1 47  ? -34.631 -18.978 44.495  1   53.74  ? 217 TRP D CZ3 1 
ATOM   389  C  CH2 . TRP A 1 47  ? -34.309 -18.495 45.766  1   53.17  ? 217 TRP D CH2 1 
ATOM   390  N  N   . LEU A 1 48  ? -39.359 -20.518 43.226  1   59.88  ? 218 LEU D N   1 
ATOM   391  C  CA  . LEU A 1 48  ? -39.823 -19.15  43.037  1   56.31  ? 218 LEU D CA  1 
ATOM   392  C  C   . LEU A 1 48  ? -41.31  -18.997 43.395  1   60.58  ? 218 LEU D C   1 
ATOM   393  O  O   . LEU A 1 48  ? -41.702 -17.978 43.958  1   60.67  ? 218 LEU D O   1 
ATOM   394  C  CB  . LEU A 1 48  ? -39.461 -18.669 41.638  1   52.81  ? 218 LEU D CB  1 
ATOM   395  C  CG  . LEU A 1 48  ? -37.974 -18.353 41.431  1   54.23  ? 218 LEU D CG  1 
ATOM   396  C  CD1 . LEU A 1 48  ? -37.697 -17.798 40.043  1   52.59  ? 218 LEU D CD1 1 
ATOM   397  C  CD2 . LEU A 1 48  ? -37.467 -17.374 42.481  1   50.89  ? 218 LEU D CD2 1 
ATOM   398  N  N   . VAL A 1 49  ? -42.129 -20.032 43.14   1   61.7   ? 219 VAL D N   1 
ATOM   399  C  CA  . VAL A 1 49  ? -43.547 -19.991 43.469  1   60.89  ? 219 VAL D CA  1 
ATOM   400  C  C   . VAL A 1 49  ? -43.717 -19.769 44.973  1   61.68  ? 219 VAL D C   1 
ATOM   401  O  O   . VAL A 1 49  ? -44.475 -18.88  45.394  1   60.1   ? 219 VAL D O   1 
ATOM   402  C  CB  . VAL A 1 49  ? -44.265 -21.266 42.984  1   62.04  ? 219 VAL D CB  1 
ATOM   403  C  CG1 . VAL A 1 49  ? -45.644 -21.411 43.619  1   63.17  ? 219 VAL D CG1 1 
ATOM   404  C  CG2 . VAL A 1 49  ? -44.36  -21.309 41.463  1   60.14  ? 219 VAL D CG2 1 
ATOM   405  N  N   . GLU A 1 50  ? -42.993 -20.592 45.754  1   63.88  ? 220 GLU D N   1 
ATOM   406  C  CA  . GLU A 1 50  ? -42.961 -20.552 47.213  1   68.16  ? 220 GLU D CA  1 
ATOM   407  C  C   . GLU A 1 50  ? -42.545 -19.176 47.721  1   64.87  ? 220 GLU D C   1 
ATOM   408  O  O   . GLU A 1 50  ? -43.154 -18.654 48.654  1   65.67  ? 220 GLU D O   1 
ATOM   409  C  CB  . GLU A 1 50  ? -41.878 -21.455 47.8    1   70.38  ? 220 GLU D CB  1 
ATOM   410  C  CG  . GLU A 1 50  ? -42.211 -22.937 47.7    1   79.91  ? 220 GLU D CG  1 
ATOM   411  C  CD  . GLU A 1 50  ? -41.533 -23.751 48.781  1   86.95  ? 220 GLU D CD  1 
ATOM   412  O  OE1 . GLU A 1 50  ? -42.264 -24.539 49.437  1   94.55  ? 220 GLU D OE1 1 
ATOM   413  O  OE2 . GLU A 1 50  ? -40.303 -23.603 48.959  1   83.42  ? 220 GLU D OE2 1 
ATOM   414  N  N   . VAL A 1 51  ? -41.476 -18.635 47.142  1   59.31  ? 221 VAL D N   1 
ATOM   415  C  CA  . VAL A 1 51  ? -40.95  -17.307 47.564  1   57.39  ? 221 VAL D CA  1 
ATOM   416  C  C   . VAL A 1 51  ? -42.024 -16.243 47.32   1   57.25  ? 221 VAL D C   1 
ATOM   417  O  O   . VAL A 1 51  ? -42.198 -15.363 48.179  1   58.9   ? 221 VAL D O   1 
ATOM   418  C  CB  . VAL A 1 51  ? -39.658 -17.03  46.779  1   52.98  ? 221 VAL D CB  1 
ATOM   419  C  CG1 . VAL A 1 51  ? -39.288 -15.554 46.77   1   50.67  ? 221 VAL D CG1 1 
ATOM   420  C  CG2 . VAL A 1 51  ? -38.499 -17.884 47.273  1   50.18  ? 221 VAL D CG2 1 
ATOM   421  N  N   . GLY A 1 52  ? -42.75  -16.36  46.215  1   54.68  ? 222 GLY D N   1 
ATOM   422  C  CA  . GLY A 1 52  ? -43.791 -15.376 45.89   1   56.62  ? 222 GLY D CA  1 
ATOM   423  C  C   . GLY A 1 52  ? -44.935 -15.432 46.87   1   60.82  ? 222 GLY D C   1 
ATOM   424  O  O   . GLY A 1 52  ? -45.687 -14.451 46.948  1   61.25  ? 222 GLY D O   1 
ATOM   425  N  N   . GLU A 1 53  ? -45.072 -16.547 47.583  1   64.64  ? 223 GLU D N   1 
ATOM   426  C  CA  . GLU A 1 53  ? -46.187 -16.719 48.547  1   72.37  ? 223 GLU D CA  1 
ATOM   427  C  C   . GLU A 1 53  ? -45.73  -16.246 49.932  1   73     ? 223 GLU D C   1 
ATOM   428  O  O   . GLU A 1 53  ? -46.538 -15.616 50.633  1   76.71  ? 223 GLU D O   1 
ATOM   429  C  CB  . GLU A 1 53  ? -46.643 -18.177 48.526  1   74.35  ? 223 GLU D CB  1 
ATOM   430  C  CG  . GLU A 1 53  ? -47.407 -18.548 47.26   1   81.52  ? 223 GLU D CG  1 
ATOM   431  C  CD  . GLU A 1 53  ? -48.217 -17.408 46.671  1   90.03  ? 223 GLU D CD  1 
ATOM   432  O  OE1 . GLU A 1 53  ? -47.741 -16.778 45.703  1   92.7   ? 223 GLU D OE1 1 
ATOM   433  O  OE2 . GLU A 1 53  ? -49.33  -17.157 47.174  1   91.6   ? 223 GLU D OE2 1 
ATOM   434  N  N   . GLU A 1 54  ? -44.478 -16.519 50.289  1   71.1   ? 224 GLU D N   1 
ATOM   435  C  CA  . GLU A 1 54  ? -43.941 -16.045 51.588  1   70.42  ? 224 GLU D CA  1 
ATOM   436  C  C   . GLU A 1 54  ? -43.862 -14.511 51.566  1   68.21  ? 224 GLU D C   1 
ATOM   437  O  O   . GLU A 1 54  ? -44.02  -13.896 52.631  1   69.76  ? 224 GLU D O   1 
ATOM   438  C  CB  . GLU A 1 54  ? -42.605 -16.736 51.853  1   71.96  ? 224 GLU D CB  1 
ATOM   439  C  CG  . GLU A 1 54  ? -41.596 -15.886 52.617  1   78.48  ? 224 GLU D CG  1 
ATOM   440  C  CD  . GLU A 1 54  ? -41.598 -16.13  54.112  1   97.67  ? 224 GLU D CD  1 
ATOM   441  O  OE1 . GLU A 1 54  ? -42.378 -16.992 54.565  1   106.38 ? 224 GLU D OE1 1 
ATOM   442  O  OE2 . GLU A 1 54  ? -40.822 -15.459 54.824  1   104.32 ? 224 GLU D OE2 1 
ATOM   443  N  N   . TYR A 1 55  ? -43.651 -13.921 50.395  1   65.61  ? 225 TYR D N   1 
ATOM   444  C  CA  . TYR A 1 55  ? -43.49  -12.447 50.313  1   66.47  ? 225 TYR D CA  1 
ATOM   445  C  C   . TYR A 1 55  ? -44.747 -11.862 49.703  1   68.93  ? 225 TYR D C   1 
ATOM   446  O  O   . TYR A 1 55  ? -44.783 -10.649 49.448  1   67.76  ? 225 TYR D O   1 
ATOM   447  C  CB  . TYR A 1 55  ? -42.178 -12.174 49.576  1   63.08  ? 225 TYR D CB  1 
ATOM   448  C  CG  . TYR A 1 55  ? -40.958 -12.487 50.427  1   66.37  ? 225 TYR D CG  1 
ATOM   449  C  CD1 . TYR A 1 55  ? -40.589 -11.659 51.478  1   68.09  ? 225 TYR D CD1 1 
ATOM   450  C  CD2 . TYR A 1 55  ? -40.193 -13.62  50.195  1   66.76  ? 225 TYR D CD2 1 
ATOM   451  C  CE1 . TYR A 1 55  ? -39.488 -11.941 52.266  1   65.88  ? 225 TYR D CE1 1 
ATOM   452  C  CE2 . TYR A 1 55  ? -39.09  -13.912 50.977  1   64.63  ? 225 TYR D CE2 1 
ATOM   453  C  CZ  . TYR A 1 55  ? -38.736 -13.072 52.014  1   64.32  ? 225 TYR D CZ  1 
ATOM   454  O  OH  . TYR A 1 55  ? -37.65  -13.357 52.786  1   66.74  ? 225 TYR D OH  1 
ATOM   455  N  N   . LYS A 1 56  ? -45.755 -12.703 49.484  1   72.85  ? 226 LYS D N   1 
ATOM   456  C  CA  . LYS A 1 56  ? -47.043 -12.235 48.973  1   73.68  ? 226 LYS D CA  1 
ATOM   457  C  C   . LYS A 1 56  ? -46.867 -11.328 47.753  1   69.52  ? 226 LYS D C   1 
ATOM   458  O  O   . LYS A 1 56  ? -47.39  -10.219 47.729  1   71.12  ? 226 LYS D O   1 
ATOM   459  C  CB  . LYS A 1 56  ? -47.918 -11.645 50.089  1   76.67  ? 226 LYS D CB  1 
ATOM   460  C  CG  . LYS A 1 56  ? -48.833 -12.69  50.739  1   85.49  ? 226 LYS D CG  1 
ATOM   461  C  CD  . LYS A 1 56  ? -49.015 -12.558 52.246  1   92.48  ? 226 LYS D CD  1 
ATOM   462  C  CE  . LYS A 1 56  ? -47.811 -13.059 53.005  1   98.45  ? 226 LYS D CE  1 
ATOM   463  N  NZ  . LYS A 1 56  ? -47.921 -12.831 54.452  1   102.37 ? 226 LYS D NZ  1 
ATOM   464  N  N   . LEU A 1 57  ? -46.151 -11.818 46.738  1   63.96  ? 227 LEU D N   1 
ATOM   465  C  CA  . LEU A 1 57  ? -45.925 -11.053 45.526  1   61.29  ? 227 LEU D CA  1 
ATOM   466  C  C   . LEU A 1 57  ? -47.041 -11.336 44.528  1   65.55  ? 227 LEU D C   1 
ATOM   467  O  O   . LEU A 1 57  ? -47.657 -12.413 44.561  1   70.21  ? 227 LEU D O   1 
ATOM   468  C  CB  . LEU A 1 57  ? -44.588 -11.475 44.926  1   56.9   ? 227 LEU D CB  1 
ATOM   469  C  CG  . LEU A 1 57  ? -43.393 -11.457 45.875  1   55.45  ? 227 LEU D CG  1 
ATOM   470  C  CD1 . LEU A 1 57  ? -42.173 -12.017 45.16   1   50.12  ? 227 LEU D CD1 1 
ATOM   471  C  CD2 . LEU A 1 57  ? -43.17  -10.046 46.388  1   52.8   ? 227 LEU D CD2 1 
ATOM   472  N  N   . GLN A 1 58  ? -47.235 -10.378 43.605  1   63.16  ? 228 GLN D N   1 
ATOM   473  C  CA  . GLN A 1 58  ? -48.093 -10.566 42.444  1   63.62  ? 228 GLN D CA  1 
ATOM   474  C  C   . GLN A 1 58  ? -47.677 -11.831 41.694  1   66.62  ? 228 GLN D C   1 
ATOM   475  O  O   . GLN A 1 58  ? -46.486 -12.14  41.59   1   64.52  ? 228 GLN D O   1 
ATOM   476  C  CB  . GLN A 1 58  ? -47.937 -9.426  41.438  1   58.72  ? 228 GLN D CB  1 
ATOM   477  C  CG  . GLN A 1 58  ? -48.314 -8.053  41.971  1   58.39  ? 228 GLN D CG  1 
ATOM   478  C  CD  . GLN A 1 58  ? -49.752 -8.039  42.432  1   61.72  ? 228 GLN D CD  1 
ATOM   479  O  OE1 . GLN A 1 58  ? -50.017 -7.951  43.628  1   60.98  ? 228 GLN D OE1 1 
ATOM   480  N  NE2 . GLN A 1 58  ? -50.693 -8.187  41.509  1   64.1   ? 228 GLN D NE2 1 
ATOM   481  N  N   . ASN A 1 59  ? -48.669 -12.545 41.156  1   68.42  ? 229 ASN D N   1 
ATOM   482  C  CA  . ASN A 1 59  ? -48.371 -13.618 40.227  1   68.73  ? 229 ASN D CA  1 
ATOM   483  C  C   . ASN A 1 59  ? -47.634 -13.074 39.012  1   61.03  ? 229 ASN D C   1 
ATOM   484  O  O   . ASN A 1 59  ? -46.824 -13.782 38.431  1   60.47  ? 229 ASN D O   1 
ATOM   485  C  CB  . ASN A 1 59  ? -49.624 -14.359 39.776  1   80.83  ? 229 ASN D CB  1 
ATOM   486  C  CG  . ASN A 1 59  ? -50.322 -15.021 40.935  1   85.42  ? 229 ASN D CG  1 
ATOM   487  O  OD1 . ASN A 1 59  ? -49.718 -15.842 41.636  1   82.97  ? 229 ASN D OD1 1 
ATOM   488  N  ND2 . ASN A 1 59  ? -51.566 -14.634 41.173  1   87.1   ? 229 ASN D ND2 1 
ATOM   489  N  N   . GLU A 1 60  ? -47.953 -11.839 38.61   1   59.59  ? 230 GLU D N   1 
ATOM   490  C  CA  . GLU A 1 60  ? -47.317 -11.241 37.439  1   58.22  ? 230 GLU D CA  1 
ATOM   491  C  C   . GLU A 1 60  ? -45.803 -11.145 37.664  1   56.02  ? 230 GLU D C   1 
ATOM   492  O  O   . GLU A 1 60  ? -45.017 -11.237 36.725  1   54.52  ? 230 GLU D O   1 
ATOM   493  C  CB  . GLU A 1 60  ? -47.981 -9.922  37.037  1   53.91  ? 230 GLU D CB  1 
ATOM   494  C  CG  . GLU A 1 60  ? -47.179 -9.1    36.031  1   52.23  ? 230 GLU D CG  1 
ATOM   495  C  CD  . GLU A 1 60  ? -47.259 -9.51   34.576  1   52.42  ? 230 GLU D CD  1 
ATOM   496  O  OE1 . GLU A 1 60  ? -48.014 -10.447 34.266  1   57.58  ? 230 GLU D OE1 1 
ATOM   497  O  OE2 . GLU A 1 60  ? -46.608 -8.865  33.741  1   49.66  ? 230 GLU D OE2 1 
ATOM   498  N  N   . THR A 1 61  ? -45.404 -10.965 38.923  1   54.34  ? 231 THR D N   1 
ATOM   499  C  CA  . THR A 1 61  ? -43.999 -10.901 39.286  1   53.49  ? 231 THR D CA  1 
ATOM   500  C  C   . THR A 1 61  ? -43.329 -12.241 38.976  1   53.86  ? 231 THR D C   1 
ATOM   501  O  O   . THR A 1 61  ? -42.241 -12.247 38.399  1   56.63  ? 231 THR D O   1 
ATOM   502  C  CB  . THR A 1 61  ? -43.837 -10.43  40.732  1   50.5   ? 231 THR D CB  1 
ATOM   503  O  OG1 . THR A 1 61  ? -44.485 -9.158  40.745  1   49.28  ? 231 THR D OG1 1 
ATOM   504  C  CG2 . THR A 1 61  ? -42.383 -10.23  41.117  1   48.72  ? 231 THR D CG2 1 
ATOM   505  N  N   . LEU A 1 62  ? -44.026 -13.346 39.285  1   52.88  ? 232 LEU D N   1 
ATOM   506  C  CA  . LEU A 1 62  ? -43.541 -14.703 39.082  1   52.68  ? 232 LEU D CA  1 
ATOM   507  C  C   . LEU A 1 62  ? -43.351 -15.012 37.596  1   54.23  ? 232 LEU D C   1 
ATOM   508  O  O   . LEU A 1 62  ? -42.46  -15.77  37.228  1   56.09  ? 232 LEU D O   1 
ATOM   509  C  CB  . LEU A 1 62  ? -44.482 -15.71  39.742  1   51.64  ? 232 LEU D CB  1 
ATOM   510  C  CG  . LEU A 1 62  ? -44.101 -17.179 39.554  1   51.75  ? 232 LEU D CG  1 
ATOM   511  C  CD1 . LEU A 1 62  ? -42.862 -17.544 40.37   1   51.29  ? 232 LEU D CD1 1 
ATOM   512  C  CD2 . LEU A 1 62  ? -45.248 -18.083 39.946  1   52.8   ? 232 LEU D CD2 1 
ATOM   513  N  N   . HIS A 1 63  ? -44.217 -14.461 36.744  1   56.58  ? 233 HIS D N   1 
ATOM   514  C  CA  . HIS A 1 63  ? -44.158 -14.761 35.319  1   59.48  ? 233 HIS D CA  1 
ATOM   515  C  C   . HIS A 1 63  ? -42.951 -14.074 34.678  1   59.43  ? 233 HIS D C   1 
ATOM   516  O  O   . HIS A 1 63  ? -42.165 -14.724 33.988  1   57.98  ? 233 HIS D O   1 
ATOM   517  C  CB  . HIS A 1 63  ? -45.471 -14.387 34.621  1   60.96  ? 233 HIS D CB  1 
ATOM   518  C  CG  . HIS A 1 63  ? -46.537 -15.412 34.773  1   62.57  ? 233 HIS D CG  1 
ATOM   519  N  ND1 . HIS A 1 63  ? -46.921 -16.236 33.738  1   63.52  ? 233 HIS D ND1 1 
ATOM   520  C  CD2 . HIS A 1 63  ? -47.289 -15.745 35.839  1   61.87  ? 233 HIS D CD2 1 
ATOM   521  C  CE1 . HIS A 1 63  ? -47.876 -17.046 34.189  1   67.16  ? 233 HIS D CE1 1 
ATOM   522  N  NE2 . HIS A 1 63  ? -48.118 -16.758 35.456  1   63.99  ? 233 HIS D NE2 1 
ATOM   523  N  N   . LEU A 1 64  ? -42.828 -12.757 34.917  1   55.3   ? 234 LEU D N   1 
ATOM   524  C  CA  . LEU A 1 64  ? -41.678 -11.975 34.505  1   49.85  ? 234 LEU D CA  1 
ATOM   525  C  C   . LEU A 1 64  ? -40.373 -12.674 34.907  1   51.54  ? 234 LEU D C   1 
ATOM   526  O  O   . LEU A 1 64  ? -39.506 -12.902 34.05   1   49.2   ? 234 LEU D O   1 
ATOM   527  C  CB  . LEU A 1 64  ? -41.798 -10.585 35.122  1   45.8   ? 234 LEU D CB  1 
ATOM   528  C  CG  . LEU A 1 64  ? -42.929 -9.705  34.587  1   45.15  ? 234 LEU D CG  1 
ATOM   529  C  CD1 . LEU A 1 64  ? -43.035 -8.456  35.458  1   43.92  ? 234 LEU D CD1 1 
ATOM   530  C  CD2 . LEU A 1 64  ? -42.715 -9.331  33.121  1   42.33  ? 234 LEU D CD2 1 
ATOM   531  N  N   . ALA A 1 65  ? -40.234 -13.006 36.205  1   48.28  ? 235 ALA D N   1 
ATOM   532  C  CA  . ALA A 1 65  ? -39.056 -13.697 36.706  1   46.91  ? 235 ALA D CA  1 
ATOM   533  C  C   . ALA A 1 65  ? -38.674 -14.867 35.794  1   48.71  ? 235 ALA D C   1 
ATOM   534  O  O   . ALA A 1 65  ? -37.505 -14.993 35.411  1   47.76  ? 235 ALA D O   1 
ATOM   535  C  CB  . ALA A 1 65  ? -39.324 -14.19  38.098  1   48.28  ? 235 ALA D CB  1 
ATOM   536  N  N   . VAL A 1 66  ? -39.666 -15.706 35.436  1   46.89  ? 236 VAL D N   1 
ATOM   537  C  CA  . VAL A 1 66  ? -39.414 -16.922 34.676  1   46.02  ? 236 VAL D CA  1 
ATOM   538  C  C   . VAL A 1 66  ? -39.023 -16.575 33.236  1   48.87  ? 236 VAL D C   1 
ATOM   539  O  O   . VAL A 1 66  ? -38.181 -17.258 32.646  1   53.57  ? 236 VAL D O   1 
ATOM   540  C  CB  . VAL A 1 66  ? -40.603 -17.898 34.741  1   44.35  ? 236 VAL D CB  1 
ATOM   541  C  CG1 . VAL A 1 66  ? -40.448 -19.044 33.76   1   42.17  ? 236 VAL D CG1 1 
ATOM   542  C  CG2 . VAL A 1 66  ? -40.821 -18.433 36.155  1   45.41  ? 236 VAL D CG2 1 
ATOM   543  N  N   . ASN A 1 67  ? -39.646 -15.525 32.668  1   47.39  ? 237 ASN D N   1 
ATOM   544  C  CA  . ASN A 1 67  ? -39.232 -14.969 31.387  1   45.42  ? 237 ASN D CA  1 
ATOM   545  C  C   . ASN A 1 67  ? -37.757 -14.541 31.444  1   47.96  ? 237 ASN D C   1 
ATOM   546  O  O   . ASN A 1 67  ? -37.012 -14.778 30.489  1   49.54  ? 237 ASN D O   1 
ATOM   547  C  CB  . ASN A 1 67  ? -40.135 -13.819 30.947  1   42.85  ? 237 ASN D CB  1 
ATOM   548  C  CG  . ASN A 1 67  ? -39.702 -13.228 29.622  1   45.31  ? 237 ASN D CG  1 
ATOM   549  O  OD1 . ASN A 1 67  ? -38.958 -12.244 29.599  1   47.03  ? 237 ASN D OD1 1 
ATOM   550  N  ND2 . ASN A 1 67  ? -40.061 -13.853 28.505  1   44.81  ? 237 ASN D ND2 1 
ATOM   551  N  N   . TYR A 1 68  ? -37.348 -13.882 32.542  1   46.23  ? 238 TYR D N   1 
ATOM   552  C  CA  . TYR A 1 68  ? -36.011 -13.308 32.65   1   50.21  ? 238 TYR D CA  1 
ATOM   553  C  C   . TYR A 1 68  ? -34.972 -14.429 32.629  1   51.83  ? 238 TYR D C   1 
ATOM   554  O  O   . TYR A 1 68  ? -33.923 -14.31  31.988  1   50.85  ? 238 TYR D O   1 
ATOM   555  C  CB  . TYR A 1 68  ? -35.85  -12.383 33.867  1   48.12  ? 238 TYR D CB  1 
ATOM   556  C  CG  . TYR A 1 68  ? -36.786 -11.181 33.882  1   46.55  ? 238 TYR D CG  1 
ATOM   557  C  CD1 . TYR A 1 68  ? -37.606 -10.891 32.787  1   44.76  ? 238 TYR D CD1 1 
ATOM   558  C  CD2 . TYR A 1 68  ? -36.872 -10.356 34.997  1   45.24  ? 238 TYR D CD2 1 
ATOM   559  C  CE1 . TYR A 1 68  ? -38.449 -9.79   32.769  1   45.61  ? 238 TYR D CE1 1 
ATOM   560  C  CE2 . TYR A 1 68  ? -37.718 -9.255  34.998  1   48.45  ? 238 TYR D CE2 1 
ATOM   561  C  CZ  . TYR A 1 68  ? -38.512 -8.975  33.887  1   50.25  ? 238 TYR D CZ  1 
ATOM   562  O  OH  . TYR A 1 68  ? -39.392 -7.93   33.857  1   50.16  ? 238 TYR D OH  1 
ATOM   563  N  N   . ILE A 1 69  ? -35.319 -15.53  33.311  1   54.53  ? 239 ILE D N   1 
ATOM   564  C  CA  . ILE A 1 69  ? -34.469 -16.7   33.489  1   51.45  ? 239 ILE D CA  1 
ATOM   565  C  C   . ILE A 1 69  ? -34.25  -17.428 32.158  1   53.47  ? 239 ILE D C   1 
ATOM   566  O  O   . ILE A 1 69  ? -33.117 -17.769 31.802  1   50.94  ? 239 ILE D O   1 
ATOM   567  C  CB  . ILE A 1 69  ? -35.098 -17.619 34.538  1   46.32  ? 239 ILE D CB  1 
ATOM   568  C  CG1 . ILE A 1 69  ? -35.074 -16.93  35.918  1   45.26  ? 239 ILE D CG1 1 
ATOM   569  C  CG2 . ILE A 1 69  ? -34.38  -18.962 34.525  1   44.34  ? 239 ILE D CG2 1 
ATOM   570  C  CD1 . ILE A 1 69  ? -35.962 -17.582 36.967  1   43.36  ? 239 ILE D CD1 1 
ATOM   571  N  N   . ASP A 1 70  ? -35.345 -17.653 31.426  1   52.17  ? 240 ASP D N   1 
ATOM   572  C  CA  . ASP A 1 70  ? -35.267 -18.429 30.205  1   51.18  ? 240 ASP D CA  1 
ATOM   573  C  C   . ASP A 1 70  ? -34.476 -17.649 29.165  1   49.3   ? 240 ASP D C   1 
ATOM   574  O  O   . ASP A 1 70  ? -33.719 -18.254 28.417  1   50.95  ? 240 ASP D O   1 
ATOM   575  C  CB  . ASP A 1 70  ? -36.633 -18.893 29.737  1   53.19  ? 240 ASP D CB  1 
ATOM   576  C  CG  . ASP A 1 70  ? -37.309 -19.917 30.632  1   54.68  ? 240 ASP D CG  1 
ATOM   577  O  OD1 . ASP A 1 70  ? -36.58  -20.811 31.107  1   52.11  ? 240 ASP D OD1 1 
ATOM   578  O  OD2 . ASP A 1 70  ? -38.562 -19.822 30.815  1   55.14  ? 240 ASP D OD2 1 
ATOM   579  N  N   . ARG A 1 71  ? -34.651 -16.326 29.134  1   47.78  ? 241 ARG D N   1 
ATOM   580  C  CA  . ARG A 1 71  ? -33.912 -15.479 28.162  1   47.18  ? 241 ARG D CA  1 
ATOM   581  C  C   . ARG A 1 71  ? -32.429 -15.427 28.561  1   47.4   ? 241 ARG D C   1 
ATOM   582  O  O   . ARG A 1 71  ? -31.573 -15.369 27.652  1   49.46  ? 241 ARG D O   1 
ATOM   583  C  CB  . ARG A 1 71  ? -34.524 -14.076 28.12   1   46.03  ? 241 ARG D CB  1 
ATOM   584  C  CG  . ARG A 1 71  ? -35.883 -14.01  27.438  1   49.85  ? 241 ARG D CG  1 
ATOM   585  C  CD  . ARG A 1 71  ? -36.387 -12.579 27.373  1   50.36  ? 241 ARG D CD  1 
ATOM   586  N  NE  . ARG A 1 71  ? -36.248 -11.873 28.651  1   51.88  ? 241 ARG D NE  1 
ATOM   587  C  CZ  . ARG A 1 71  ? -36.306 -10.554 28.779  1   52.98  ? 241 ARG D CZ  1 
ATOM   588  N  NH1 . ARG A 1 71  ? -37.185 -10.007 29.598  1   52.23  ? 241 ARG D NH1 1 
ATOM   589  N  NH2 . ARG A 1 71  ? -35.492 -9.784  28.08   1   52.37  ? 241 ARG D NH2 1 
ATOM   590  N  N   . PHE A 1 72  ? -32.142 -15.447 29.864  1   44.4   ? 242 PHE D N   1 
ATOM   591  C  CA  . PHE A 1 72  ? -30.771 -15.387 30.337  1   43.69  ? 242 PHE D CA  1 
ATOM   592  C  C   . PHE A 1 72  ? -30.053 -16.694 30      1   46.7   ? 242 PHE D C   1 
ATOM   593  O  O   . PHE A 1 72  ? -28.978 -16.672 29.392  1   49.79  ? 242 PHE D O   1 
ATOM   594  C  CB  . PHE A 1 72  ? -30.741 -15.006 31.816  1   41.71  ? 242 PHE D CB  1 
ATOM   595  C  CG  . PHE A 1 72  ? -29.329 -14.904 32.371  1   41.11  ? 242 PHE D CG  1 
ATOM   596  C  CD1 . PHE A 1 72  ? -28.662 -16.038 32.851  1   42.02  ? 242 PHE D CD1 1 
ATOM   597  C  CD2 . PHE A 1 72  ? -28.691 -13.679 32.427  1   40     ? 242 PHE D CD2 1 
ATOM   598  C  CE1 . PHE A 1 72  ? -27.39  -15.957 33.372  1   41.04  ? 242 PHE D CE1 1 
ATOM   599  C  CE2 . PHE A 1 72  ? -27.415 -13.594 32.945  1   42.74  ? 242 PHE D CE2 1 
ATOM   600  C  CZ  . PHE A 1 72  ? -26.773 -14.732 33.412  1   44.04  ? 242 PHE D CZ  1 
ATOM   601  N  N   . LEU A 1 73  ? -30.666 -17.831 30.357  1   45.3   ? 243 LEU D N   1 
ATOM   602  C  CA  . LEU A 1 73  ? -30.098 -19.125 30.026  1   47.26  ? 243 LEU D CA  1 
ATOM   603  C  C   . LEU A 1 73  ? -30.126 -19.411 28.518  1   50.2   ? 243 LEU D C   1 
ATOM   604  O  O   . LEU A 1 73  ? -29.58  -20.432 28.08   1   53     ? 243 LEU D O   1 
ATOM   605  C  CB  . LEU A 1 73  ? -30.879 -20.185 30.795  1   47.52  ? 243 LEU D CB  1 
ATOM   606  C  CG  . LEU A 1 73  ? -30.817 -20.059 32.312  1   48.07  ? 243 LEU D CG  1 
ATOM   607  C  CD1 . LEU A 1 73  ? -31.779 -21.074 32.912  1   46.7   ? 243 LEU D CD1 1 
ATOM   608  C  CD2 . LEU A 1 73  ? -29.384 -20.26  32.798  1   47.41  ? 243 LEU D CD2 1 
ATOM   609  N  N   . SER A 1 74  ? -30.782 -18.549 27.731  1   49.6   ? 244 SER D N   1 
ATOM   610  C  CA  . SER A 1 74  ? -30.792 -18.683 26.279  1   52.27  ? 244 SER D CA  1 
ATOM   611  C  C   . SER A 1 74  ? -29.527 -18.088 25.675  1   52.11  ? 244 SER D C   1 
ATOM   612  O  O   . SER A 1 74  ? -29.248 -18.316 24.503  1   49.75  ? 244 SER D O   1 
ATOM   613  C  CB  . SER A 1 74  ? -32.012 -18.051 25.681  1   52.56  ? 244 SER D CB  1 
ATOM   614  O  OG  . SER A 1 74  ? -33.155 -18.862 25.94   1   57.9   ? 244 SER D OG  1 
ATOM   615  N  N   . SER A 1 75  ? -28.776 -17.338 26.501  1   56.82  ? 245 SER D N   1 
ATOM   616  C  CA  . SER A 1 75  ? -27.591 -16.61  26.067  1   58.73  ? 245 SER D CA  1 
ATOM   617  C  C   . SER A 1 75  ? -26.361 -17.011 26.883  1   55.06  ? 245 SER D C   1 
ATOM   618  O  O   . SER A 1 75  ? -25.252 -16.823 26.418  1   61.61  ? 245 SER D O   1 
ATOM   619  C  CB  . SER A 1 75  ? -27.814 -15.095 26.107  1   62.68  ? 245 SER D CB  1 
ATOM   620  O  OG  . SER A 1 75  ? -29.195 -14.753 25.977  1   64.59  ? 245 SER D OG  1 
ATOM   621  N  N   . MET A 1 76  ? -26.522 -17.526 28.109  1   52.89  ? 246 MET D N   1 
ATOM   622  C  CA  . MET A 1 76  ? -25.371 -17.72  28.999  1   53.72  ? 246 MET D CA  1 
ATOM   623  C  C   . MET A 1 76  ? -25.335 -19.145 29.559  1   56.37  ? 246 MET D C   1 
ATOM   624  O  O   . MET A 1 76  ? -26.314 -19.621 30.146  1   59.76  ? 246 MET D O   1 
ATOM   625  C  CB  . MET A 1 76  ? -25.387 -16.766 30.203  1   48.14  ? 246 MET D CB  1 
ATOM   626  C  CG  . MET A 1 76  ? -25.592 -15.315 29.854  1   48.22  ? 246 MET D CG  1 
ATOM   627  S  SD  . MET A 1 76  ? -24.118 -14.501 29.223  1   52.07  ? 246 MET D SD  1 
ATOM   628  C  CE  . MET A 1 76  ? -23.246 -14.607 30.795  1   48.39  ? 246 MET D CE  1 
ATOM   629  N  N   . SER A 1 77  ? -24.208 -19.826 29.335  1   53.15  ? 247 SER D N   1 
ATOM   630  C  CA  . SER A 1 77  ? -23.928 -21.07  30.024  1   54.11  ? 247 SER D CA  1 
ATOM   631  C  C   . SER A 1 77  ? -23.887 -20.771 31.518  1   53.58  ? 247 SER D C   1 
ATOM   632  O  O   . SER A 1 77  ? -23.309 -19.76  31.913  1   57.75  ? 247 SER D O   1 
ATOM   633  C  CB  . SER A 1 77  ? -22.607 -21.651 29.57   1   54.06  ? 247 SER D CB  1 
ATOM   634  O  OG  . SER A 1 77  ? -22.655 -21.989 28.19   1   54.76  ? 247 SER D OG  1 
ATOM   635  N  N   . VAL A 1 78  ? -24.539 -21.628 32.315  1   49.83  ? 248 VAL D N   1 
ATOM   636  C  CA  . VAL A 1 78  ? -24.575 -21.493 33.761  1   48.28  ? 248 VAL D CA  1 
ATOM   637  C  C   . VAL A 1 78  ? -24.369 -22.865 34.398  1   51.8   ? 248 VAL D C   1 
ATOM   638  O  O   . VAL A 1 78  ? -24.908 -23.854 33.903  1   53.69  ? 248 VAL D O   1 
ATOM   639  C  CB  . VAL A 1 78  ? -25.889 -20.855 34.236  1   45.15  ? 248 VAL D CB  1 
ATOM   640  C  CG1 . VAL A 1 78  ? -25.977 -20.873 35.755  1   41.12  ? 248 VAL D CG1 1 
ATOM   641  C  CG2 . VAL A 1 78  ? -26.063 -19.441 33.682  1   42.22  ? 248 VAL D CG2 1 
ATOM   642  N  N   . LEU A 1 79  ? -23.563 -22.891 35.455  1   51.46  ? 249 LEU D N   1 
ATOM   643  C  CA  . LEU A 1 79  ? -23.339 -24.124 36.233  1   53.79  ? 249 LEU D CA  1 
ATOM   644  C  C   . LEU A 1 79  ? -24.433 -24.3   37.302  1   56.05  ? 249 LEU D C   1 
ATOM   645  O  O   . LEU A 1 79  ? -25     -23.31  37.726  1   55.93  ? 249 LEU D O   1 
ATOM   646  C  CB  . LEU A 1 79  ? -21.931 -24.08  36.812  1   56.58  ? 249 LEU D CB  1 
ATOM   647  C  CG  . LEU A 1 79  ? -20.779 -24.062 35.807  1   58.58  ? 249 LEU D CG  1 
ATOM   648  C  CD1 . LEU A 1 79  ? -19.501 -24.415 36.524  1   56.44  ? 249 LEU D CD1 1 
ATOM   649  C  CD2 . LEU A 1 79  ? -21.013 -24.989 34.636  1   57.56  ? 249 LEU D CD2 1 
ATOM   650  N  N   . ARG A 1 80  ? -24.739 -25.544 37.676  1   57.75  ? 250 ARG D N   1 
ATOM   651  C  CA  . ARG A 1 80  ? -25.859 -25.8   38.622  1   58.81  ? 250 ARG D CA  1 
ATOM   652  C  C   . ARG A 1 80  ? -25.744 -24.918 39.875  1   55.27  ? 250 ARG D C   1 
ATOM   653  O  O   . ARG A 1 80  ? -26.755 -24.283 40.24   1   52.39  ? 250 ARG D O   1 
ATOM   654  C  CB  . ARG A 1 80  ? -25.868 -27.285 38.996  1   59.99  ? 250 ARG D CB  1 
ATOM   655  C  CG  . ARG A 1 80  ? -27.015 -27.699 39.907  1   62.62  ? 250 ARG D CG  1 
ATOM   656  C  CD  . ARG A 1 80  ? -26.898 -29.162 40.299  1   68.27  ? 250 ARG D CD  1 
ATOM   657  N  NE  . ARG A 1 80  ? -26.132 -29.932 39.313  1   67.51  ? 250 ARG D NE  1 
ATOM   658  C  CZ  . ARG A 1 80  ? -25.077 -30.684 39.594  1   69.77  ? 250 ARG D CZ  1 
ATOM   659  N  NH1 . ARG A 1 80  ? -24.905 -31.838 38.976  1   69.48  ? 250 ARG D NH1 1 
ATOM   660  N  NH2 . ARG A 1 80  ? -24.197 -30.277 40.491  1   69.89  ? 250 ARG D NH2 1 
ATOM   661  N  N   . GLY A 1 81  ? -24.574 -24.887 40.517  1   54     ? 251 GLY D N   1 
ATOM   662  C  CA  . GLY A 1 81  ? -24.428 -24.142 41.764  1   52.33  ? 251 GLY D CA  1 
ATOM   663  C  C   . GLY A 1 81  ? -24.659 -22.677 41.596  1   52.83  ? 251 GLY D C   1 
ATOM   664  O  O   . GLY A 1 81  ? -24.651 -21.975 42.596  1   55.84  ? 251 GLY D O   1 
ATOM   665  N  N   . LYS A 1 82  ? -24.9   -22.244 40.37   1   50.99  ? 252 LYS D N   1 
ATOM   666  C  CA  . LYS A 1 82  ? -25.209 -20.834 40.211  1   48.07  ? 252 LYS D CA  1 
ATOM   667  C  C   . LYS A 1 82  ? -26.627 -20.625 39.678  1   46.2   ? 252 LYS D C   1 
ATOM   668  O  O   . LYS A 1 82  ? -27.074 -19.479 39.587  1   44.95  ? 252 LYS D O   1 
ATOM   669  C  CB  . LYS A 1 82  ? -24.188 -20.173 39.275  1   48.05  ? 252 LYS D CB  1 
ATOM   670  C  CG  . LYS A 1 82  ? -22.778 -20.088 39.826  1   48.14  ? 252 LYS D CG  1 
ATOM   671  C  CD  . LYS A 1 82  ? -22.737 -19.112 40.991  1   47.62  ? 252 LYS D CD  1 
ATOM   672  C  CE  . LYS A 1 82  ? -21.355 -18.788 41.47   1   49.7   ? 252 LYS D CE  1 
ATOM   673  N  NZ  . LYS A 1 82  ? -20.708 -20.058 41.823  1   54.01  ? 252 LYS D NZ  1 
ATOM   674  N  N   . LEU A 1 83  ? -27.324 -21.717 39.324  1   45.37  ? 253 LEU D N   1 
ATOM   675  C  CA  . LEU A 1 83  ? -28.666 -21.636 38.758  1   45.05  ? 253 LEU D CA  1 
ATOM   676  C  C   . LEU A 1 83  ? -29.586 -20.845 39.687  1   48.03  ? 253 LEU D C   1 
ATOM   677  O  O   . LEU A 1 83  ? -30.345 -19.988 39.24   1   50.47  ? 253 LEU D O   1 
ATOM   678  C  CB  . LEU A 1 83  ? -29.182 -23.056 38.539  1   45.51  ? 253 LEU D CB  1 
ATOM   679  C  CG  . LEU A 1 83  ? -30.608 -23.183 37.996  1   45.94  ? 253 LEU D CG  1 
ATOM   680  C  CD1 . LEU A 1 83  ? -30.769 -22.47  36.652  1   42.55  ? 253 LEU D CD1 1 
ATOM   681  C  CD2 . LEU A 1 83  ? -30.936 -24.677 37.842  1   47.58  ? 253 LEU D CD2 1 
ATOM   682  N  N   . GLN A 1 84  ? -29.491 -21.114 40.995  1   48.65  ? 254 GLN D N   1 
ATOM   683  C  CA  . GLN A 1 84  ? -30.295 -20.394 41.968  1   49.24  ? 254 GLN D CA  1 
ATOM   684  C  C   . GLN A 1 84  ? -29.941 -18.897 42.004  1   50.3   ? 254 GLN D C   1 
ATOM   685  O  O   . GLN A 1 84  ? -30.819 -18.07  42.263  1   51.45  ? 254 GLN D O   1 
ATOM   686  C  CB  . GLN A 1 84  ? -30.192 -21.047 43.343  1   47.82  ? 254 GLN D CB  1 
ATOM   687  C  CG  . GLN A 1 84  ? -31.24  -20.51  44.307  1   51     ? 254 GLN D CG  1 
ATOM   688  C  CD  . GLN A 1 84  ? -31.181 -21.121 45.691  1   58.39  ? 254 GLN D CD  1 
ATOM   689  O  OE1 . GLN A 1 84  ? -32.062 -20.896 46.531  1   59.38  ? 254 GLN D OE1 1 
ATOM   690  N  NE2 . GLN A 1 84  ? -30.135 -21.899 45.943  1   61.89  ? 254 GLN D NE2 1 
ATOM   691  N  N   . LEU A 1 85  ? -28.663 -18.55  41.774  1   46.1   ? 255 LEU D N   1 
ATOM   692  C  CA  . LEU A 1 85  ? -28.24  -17.162 41.849  1   47.05  ? 255 LEU D CA  1 
ATOM   693  C  C   . LEU A 1 85  ? -28.922 -16.369 40.734  1   48.25  ? 255 LEU D C   1 
ATOM   694  O  O   . LEU A 1 85  ? -29.372 -15.25  40.946  1   49.85  ? 255 LEU D O   1 
ATOM   695  C  CB  . LEU A 1 85  ? -26.716 -17.089 41.766  1   47.05  ? 255 LEU D CB  1 
ATOM   696  C  CG  . LEU A 1 85  ? -26.075 -15.698 41.791  1   45.86  ? 255 LEU D CG  1 
ATOM   697  C  CD1 . LEU A 1 85  ? -26.33  -14.922 43.07   1   44.77  ? 255 LEU D CD1 1 
ATOM   698  C  CD2 . LEU A 1 85  ? -24.572 -15.842 41.614  1   46.08  ? 255 LEU D CD2 1 
ATOM   699  N  N   . VAL A 1 86  ? -29.022 -16.98  39.552  1   49.45  ? 256 VAL D N   1 
ATOM   700  C  CA  . VAL A 1 86  ? -29.708 -16.383 38.418  1   46.99  ? 256 VAL D CA  1 
ATOM   701  C  C   . VAL A 1 86  ? -31.182 -16.146 38.749  1   48.84  ? 256 VAL D C   1 
ATOM   702  O  O   . VAL A 1 86  ? -31.739 -15.098 38.411  1   45.31  ? 256 VAL D O   1 
ATOM   703  C  CB  . VAL A 1 86  ? -29.593 -17.32  37.205  1   45.07  ? 256 VAL D CB  1 
ATOM   704  C  CG1 . VAL A 1 86  ? -30.464 -16.824 36.049  1   42.01  ? 256 VAL D CG1 1 
ATOM   705  C  CG2 . VAL A 1 86  ? -28.133 -17.525 36.796  1   44.67  ? 256 VAL D CG2 1 
ATOM   706  N  N   . GLY A 1 87  ? -31.811 -17.154 39.376  1   49.06  ? 257 GLY D N   1 
ATOM   707  C  CA  . GLY A 1 87  ? -33.24  -17.118 39.63   1   46.13  ? 257 GLY D CA  1 
ATOM   708  C  C   . GLY A 1 87  ? -33.563 -16.079 40.695  1   49.1   ? 257 GLY D C   1 
ATOM   709  O  O   . GLY A 1 87  ? -34.583 -15.399 40.591  1   52.04  ? 257 GLY D O   1 
ATOM   710  N  N   . THR A 1 88  ? -32.691 -15.977 41.717  1   46.95  ? 258 THR D N   1 
ATOM   711  C  CA  . THR A 1 88  ? -32.872 -15.038 42.811  1   45.93  ? 258 THR D CA  1 
ATOM   712  C  C   . THR A 1 88  ? -32.763 -13.634 42.231  1   46.1   ? 258 THR D C   1 
ATOM   713  O  O   . THR A 1 88  ? -33.546 -12.756 42.583  1   46.12  ? 258 THR D O   1 
ATOM   714  C  CB  . THR A 1 88  ? -31.819 -15.288 43.89   1   47.21  ? 258 THR D CB  1 
ATOM   715  O  OG1 . THR A 1 88  ? -31.906 -16.672 44.228  1   56.06  ? 258 THR D OG1 1 
ATOM   716  C  CG2 . THR A 1 88  ? -32.034 -14.479 45.148  1   43.94  ? 258 THR D CG2 1 
ATOM   717  N  N   . ALA A 1 89  ? -31.795 -13.443 41.325  1   45     ? 259 ALA D N   1 
ATOM   718  C  CA  . ALA A 1 89  ? -31.559 -12.14  40.73   1   44.33  ? 259 ALA D CA  1 
ATOM   719  C  C   . ALA A 1 89  ? -32.725 -11.755 39.828  1   45.45  ? 259 ALA D C   1 
ATOM   720  O  O   . ALA A 1 89  ? -33.091 -10.585 39.779  1   51.94  ? 259 ALA D O   1 
ATOM   721  C  CB  . ALA A 1 89  ? -30.258 -12.128 39.999  1   41.33  ? 259 ALA D CB  1 
ATOM   722  N  N   . ALA A 1 90  ? -33.329 -12.73  39.14   1   42.57  ? 260 ALA D N   1 
ATOM   723  C  CA  . ALA A 1 90  ? -34.482 -12.456 38.289  1   42.67  ? 260 ALA D CA  1 
ATOM   724  C  C   . ALA A 1 90  ? -35.721 -12.062 39.111  1   44.43  ? 260 ALA D C   1 
ATOM   725  O  O   . ALA A 1 90  ? -36.474 -11.148 38.771  1   50.37  ? 260 ALA D O   1 
ATOM   726  C  CB  . ALA A 1 90  ? -34.751 -13.663 37.443  1   40.05  ? 260 ALA D CB  1 
ATOM   727  N  N   . MET A 1 91  ? -35.95  -12.776 40.199  1   42.38  ? 261 MET D N   1 
ATOM   728  C  CA  . MET A 1 91  ? -37.085 -12.485 41.047  1   44.18  ? 261 MET D CA  1 
ATOM   729  C  C   . MET A 1 91  ? -36.895 -11.068 41.574  1   45.23  ? 261 MET D C   1 
ATOM   730  O  O   . MET A 1 91  ? -37.832 -10.287 41.545  1   48.94  ? 261 MET D O   1 
ATOM   731  C  CB  . MET A 1 91  ? -37.135 -13.5   42.196  1   46.64  ? 261 MET D CB  1 
ATOM   732  C  CG  . MET A 1 91  ? -38.469 -13.648 42.851  1   52.84  ? 261 MET D CG  1 
ATOM   733  S  SD  . MET A 1 91  ? -39.725 -14.155 41.666  1   58.42  ? 261 MET D SD  1 
ATOM   734  C  CE  . MET A 1 91  ? -41.101 -14.459 42.772  1   54.11  ? 261 MET D CE  1 
ATOM   735  N  N   . LEU A 1 92  ? -35.665 -10.733 42.002  1   44.82  ? 262 LEU D N   1 
ATOM   736  C  CA  . LEU A 1 92  ? -35.371 -9.408  42.517  1   43.31  ? 262 LEU D CA  1 
ATOM   737  C  C   . LEU A 1 92  ? -35.706 -8.366  41.447  1   44.21  ? 262 LEU D C   1 
ATOM   738  O  O   . LEU A 1 92  ? -36.397 -7.376  41.706  1   46.11  ? 262 LEU D O   1 
ATOM   739  C  CB  . LEU A 1 92  ? -33.917 -9.322  42.957  1   41.55  ? 262 LEU D CB  1 
ATOM   740  C  CG  . LEU A 1 92  ? -33.42  -7.908  43.275  1   41.61  ? 262 LEU D CG  1 
ATOM   741  C  CD1 . LEU A 1 92  ? -34.266 -7.242  44.359  1   41.15  ? 262 LEU D CD1 1 
ATOM   742  C  CD2 . LEU A 1 92  ? -31.935 -7.9    43.657  1   40.87  ? 262 LEU D CD2 1 
ATOM   743  N  N   . LEU A 1 93  ? -35.239 -8.621  40.223  1   42.11  ? 263 LEU D N   1 
ATOM   744  C  CA  . LEU A 1 93  ? -35.47  -7.708  39.124  1   41.44  ? 263 LEU D CA  1 
ATOM   745  C  C   . LEU A 1 93  ? -36.966 -7.6    38.843  1   44.5   ? 263 LEU D C   1 
ATOM   746  O  O   . LEU A 1 93  ? -37.457 -6.49   38.635  1   49.52  ? 263 LEU D O   1 
ATOM   747  C  CB  . LEU A 1 93  ? -34.674 -8.163  37.905  1   41.35  ? 263 LEU D CB  1 
ATOM   748  C  CG  . LEU A 1 93  ? -33.22  -7.684  37.843  1   42.58  ? 263 LEU D CG  1 
ATOM   749  C  CD1 . LEU A 1 93  ? -32.493 -8.428  36.701  1   39.55  ? 263 LEU D CD1 1 
ATOM   750  C  CD2 . LEU A 1 93  ? -33.104 -6.145  37.723  1   41.92  ? 263 LEU D CD2 1 
ATOM   751  N  N   . ALA A 1 94  ? -37.684 -8.736  38.813  1   43.86  ? 264 ALA D N   1 
ATOM   752  C  CA  . ALA A 1 94  ? -39.113 -8.722  38.511  1   44.22  ? 264 ALA D CA  1 
ATOM   753  C  C   . ALA A 1 94  ? -39.881 -7.95   39.576  1   46.27  ? 264 ALA D C   1 
ATOM   754  O  O   . ALA A 1 94  ? -40.802 -7.216  39.261  1   47.41  ? 264 ALA D O   1 
ATOM   755  C  CB  . ALA A 1 94  ? -39.651 -10.113 38.374  1   44.56  ? 264 ALA D CB  1 
ATOM   756  N  N   . SER A 1 95  ? -39.469 -8.101  40.837  1   46.78  ? 265 SER D N   1 
ATOM   757  C  CA  . SER A 1 95  ? -40.033 -7.346  41.94   1   49.01  ? 265 SER D CA  1 
ATOM   758  C  C   . SER A 1 95  ? -39.788 -5.843  41.772  1   52.32  ? 265 SER D C   1 
ATOM   759  O  O   . SER A 1 95  ? -40.71  -5.031  41.961  1   54.14  ? 265 SER D O   1 
ATOM   760  C  CB  . SER A 1 95  ? -39.488 -7.839  43.245  1   48.83  ? 265 SER D CB  1 
ATOM   761  O  OG  . SER A 1 95  ? -39.841 -9.204  43.426  1   49.69  ? 265 SER D OG  1 
ATOM   762  N  N   . LYS A 1 96  ? -38.548 -5.462  41.427  1   46.57  ? 266 LYS D N   1 
ATOM   763  C  CA  . LYS A 1 96  ? -38.276 -4.047  41.262  1   44.2   ? 266 LYS D CA  1 
ATOM   764  C  C   . LYS A 1 96  ? -39.135 -3.49   40.131  1   45.86  ? 266 LYS D C   1 
ATOM   765  O  O   . LYS A 1 96  ? -39.592 -2.357  40.221  1   48.31  ? 266 LYS D O   1 
ATOM   766  C  CB  . LYS A 1 96  ? -36.785 -3.827  41.04   1   42.83  ? 266 LYS D CB  1 
ATOM   767  C  CG  . LYS A 1 96  ? -35.997 -3.87   42.328  1   43.65  ? 266 LYS D CG  1 
ATOM   768  C  CD  . LYS A 1 96  ? -34.506 -3.779  42.011  1   43.42  ? 266 LYS D CD  1 
ATOM   769  C  CE  . LYS A 1 96  ? -33.623 -3.468  43.182  1   44.08  ? 266 LYS D CE  1 
ATOM   770  N  NZ  . LYS A 1 96  ? -32.248 -3.387  42.679  1   44.27  ? 266 LYS D NZ  1 
ATOM   771  N  N   . PHE A 1 97  ? -39.377 -4.294  39.089  1   43.81  ? 267 PHE D N   1 
ATOM   772  C  CA  . PHE A 1 97  ? -40.136 -3.825  37.944  1   46.37  ? 267 PHE D CA  1 
ATOM   773  C  C   . PHE A 1 97  ? -41.608 -3.628  38.31   1   48.44  ? 267 PHE D C   1 
ATOM   774  O  O   . PHE A 1 97  ? -42.169 -2.555  38.053  1   44.77  ? 267 PHE D O   1 
ATOM   775  C  CB  . PHE A 1 97  ? -39.94  -4.739  36.733  1   45.5   ? 267 PHE D CB  1 
ATOM   776  C  CG  . PHE A 1 97  ? -40.662 -4.277  35.471  1   49.7   ? 267 PHE D CG  1 
ATOM   777  C  CD1 . PHE A 1 97  ? -40.106 -3.31   34.624  1   50.43  ? 267 PHE D CD1 1 
ATOM   778  C  CD2 . PHE A 1 97  ? -41.9   -4.817  35.121  1   52.35  ? 267 PHE D CD2 1 
ATOM   779  C  CE1 . PHE A 1 97  ? -40.766 -2.905  33.46   1   50.26  ? 267 PHE D CE1 1 
ATOM   780  C  CE2 . PHE A 1 97  ? -42.552 -4.421  33.949  1   51.66  ? 267 PHE D CE2 1 
ATOM   781  C  CZ  . PHE A 1 97  ? -41.993 -3.459  33.128  1   51.26  ? 267 PHE D CZ  1 
ATOM   782  N  N   . GLU A 1 98  ? -42.187 -4.655  38.96   1   50.31  ? 268 GLU D N   1 
ATOM   783  C  CA  . GLU A 1 98  ? -43.628 -4.862  39.009  1   51.63  ? 268 GLU D CA  1 
ATOM   784  C  C   . GLU A 1 98  ? -44.251 -4.475  40.351  1   54.15  ? 268 GLU D C   1 
ATOM   785  O  O   . GLU A 1 98  ? -45.404 -4.069  40.369  1   62.4   ? 268 GLU D O   1 
ATOM   786  C  CB  . GLU A 1 98  ? -43.989 -6.326  38.77   1   50.91  ? 268 GLU D CB  1 
ATOM   787  C  CG  . GLU A 1 98  ? -45.468 -6.537  38.455  1   54.22  ? 268 GLU D CG  1 
ATOM   788  C  CD  . GLU A 1 98  ? -45.989 -5.825  37.212  1   55.3   ? 268 GLU D CD  1 
ATOM   789  O  OE1 . GLU A 1 98  ? -45.176 -5.499  36.307  1   51.23  ? 268 GLU D OE1 1 
ATOM   790  O  OE2 . GLU A 1 98  ? -47.22  -5.563  37.178  1   55.59  ? 268 GLU D OE2 1 
ATOM   791  N  N   . GLU A 1 99  ? -43.535 -4.632  41.471  1   53.99  ? 269 GLU D N   1 
ATOM   792  C  CA  . GLU A 1 99  ? -44.153 -4.493  42.783  1   53.92  ? 269 GLU D CA  1 
ATOM   793  C  C   . GLU A 1 99  ? -44.155 -3.036  43.238  1   56.77  ? 269 GLU D C   1 
ATOM   794  O  O   . GLU A 1 99  ? -43.187 -2.306  43.062  1   57.03  ? 269 GLU D O   1 
ATOM   795  C  CB  . GLU A 1 99  ? -43.42  -5.337  43.827  1   52.38  ? 269 GLU D CB  1 
ATOM   796  C  CG  . GLU A 1 99  ? -43.544 -6.844  43.613  1   52.25  ? 269 GLU D CG  1 
ATOM   797  C  CD  . GLU A 1 99  ? -44.906 -7.437  43.952  1   55.76  ? 269 GLU D CD  1 
ATOM   798  O  OE1 . GLU A 1 99  ? -45.436 -7.158  45.054  1   57.41  ? 269 GLU D OE1 1 
ATOM   799  O  OE2 . GLU A 1 99  ? -45.43  -8.204  43.118  1   54.43  ? 269 GLU D OE2 1 
ATOM   800  N  N   . ILE A 1 100 ? -45.238 -2.643  43.911  1   59.89  ? 270 ILE D N   1 
ATOM   801  C  CA  . ILE A 1 100 ? -45.291 -1.369  44.605  1   59.1   ? 270 ILE D CA  1 
ATOM   802  C  C   . ILE A 1 100 ? -44.238 -1.312  45.718  1   60.25  ? 270 ILE D C   1 
ATOM   803  O  O   . ILE A 1 100 ? -43.53  -0.316  45.837  1   59.84  ? 270 ILE D O   1 
ATOM   804  C  CB  . ILE A 1 100 ? -46.698 -1.136  45.169  1   57.79  ? 270 ILE D CB  1 
ATOM   805  C  CG1 . ILE A 1 100 ? -47.742 -1.096  44.058  1   57.28  ? 270 ILE D CG1 1 
ATOM   806  C  CG2 . ILE A 1 100 ? -46.699 0.142   46.006  1   58.76  ? 270 ILE D CG2 1 
ATOM   807  C  CD1 . ILE A 1 100 ? -49.171 -1.179  44.555  1   57.62  ? 270 ILE D CD1 1 
ATOM   808  N  N   . TYR A 1 101 ? -44.198 -2.366  46.552  1   61.28  ? 271 TYR D N   1 
ATOM   809  C  CA  . TYR A 1 101 ? -43.318 -2.465  47.712  1   60.88  ? 271 TYR D CA  1 
ATOM   810  C  C   . TYR A 1 101 ? -42.446 -3.718  47.575  1   61.07  ? 271 TYR D C   1 
ATOM   811  O  O   . TYR A 1 101 ? -42.708 -4.734  48.226  1   63.32  ? 271 TYR D O   1 
ATOM   812  C  CB  . TYR A 1 101 ? -44.152 -2.536  48.999  1   61.93  ? 271 TYR D CB  1 
ATOM   813  C  CG  . TYR A 1 101 ? -45.076 -1.351  49.265  1   68.14  ? 271 TYR D CG  1 
ATOM   814  C  CD1 . TYR A 1 101 ? -44.563 -0.115  49.675  1   66.71  ? 271 TYR D CD1 1 
ATOM   815  C  CD2 . TYR A 1 101 ? -46.469 -1.462  49.105  1   69.21  ? 271 TYR D CD2 1 
ATOM   816  C  CE1 . TYR A 1 101 ? -45.4   0.968   49.915  1   69.09  ? 271 TYR D CE1 1 
ATOM   817  C  CE2 . TYR A 1 101 ? -47.312 -0.379  49.339  1   70.83  ? 271 TYR D CE2 1 
ATOM   818  C  CZ  . TYR A 1 101 ? -46.775 0.839   49.743  1   73.18  ? 271 TYR D CZ  1 
ATOM   819  O  OH  . TYR A 1 101 ? -47.598 1.914   49.976  1   79.23  ? 271 TYR D OH  1 
ATOM   820  N  N   . PRO A 1 102 ? -41.393 -3.717  46.715  1   56.77  ? 272 PRO D N   1 
ATOM   821  C  CA  . PRO A 1 102 ? -40.536 -4.9    46.55   1   52.78  ? 272 PRO D CA  1 
ATOM   822  C  C   . PRO A 1 102 ? -39.862 -5.293  47.864  1   53.86  ? 272 PRO D C   1 
ATOM   823  O  O   . PRO A 1 102 ? -39.599 -4.447  48.722  1   57.83  ? 272 PRO D O   1 
ATOM   824  C  CB  . PRO A 1 102 ? -39.478 -4.51   45.515  1   47.62  ? 272 PRO D CB  1 
ATOM   825  C  CG  . PRO A 1 102 ? -39.622 -3.016  45.335  1   50.07  ? 272 PRO D CG  1 
ATOM   826  C  CD  . PRO A 1 102 ? -40.97  -2.583  45.881  1   52.82  ? 272 PRO D CD  1 
ATOM   827  N  N   . PRO A 1 103 ? -39.566 -6.587  48.089  1   51.38  ? 273 PRO D N   1 
ATOM   828  C  CA  . PRO A 1 103 ? -38.685 -6.966  49.188  1   52.26  ? 273 PRO D CA  1 
ATOM   829  C  C   . PRO A 1 103 ? -37.317 -6.333  48.972  1   52.04  ? 273 PRO D C   1 
ATOM   830  O  O   . PRO A 1 103 ? -36.872 -6.167  47.836  1   48.31  ? 273 PRO D O   1 
ATOM   831  C  CB  . PRO A 1 103 ? -38.625 -8.492  49.121  1   51.52  ? 273 PRO D CB  1 
ATOM   832  C  CG  . PRO A 1 103 ? -39.829 -8.873  48.291  1   52.35  ? 273 PRO D CG  1 
ATOM   833  C  CD  . PRO A 1 103 ? -40.108 -7.728  47.347  1   50.73  ? 273 PRO D CD  1 
ATOM   834  N  N   . GLU A 1 104 ? -36.646 -6.001  50.08   1   55.82  ? 274 GLU D N   1 
ATOM   835  C  CA  . GLU A 1 104 ? -35.272 -5.541  49.999  1   60.12  ? 274 GLU D CA  1 
ATOM   836  C  C   . GLU A 1 104 ? -34.354 -6.672  49.56   1   57.48  ? 274 GLU D C   1 
ATOM   837  O  O   . GLU A 1 104 ? -34.74  -7.831  49.582  1   59.22  ? 274 GLU D O   1 
ATOM   838  C  CB  . GLU A 1 104 ? -34.876 -4.946  51.344  1   68.72  ? 274 GLU D CB  1 
ATOM   839  C  CG  . GLU A 1 104 ? -35.466 -3.553  51.545  1   76.04  ? 274 GLU D CG  1 
ATOM   840  C  CD  . GLU A 1 104 ? -35.616 -3.313  53.029  1   89.15  ? 274 GLU D CD  1 
ATOM   841  O  OE1 . GLU A 1 104 ? -35.325 -2.189  53.499  1   101    ? 274 GLU D OE1 1 
ATOM   842  O  OE2 . GLU A 1 104 ? -35.993 -4.293  53.716  1   91.86  ? 274 GLU D OE2 1 
ATOM   843  N  N   . VAL A 1 105 ? -33.143 -6.309  49.142  1   53.98  ? 275 VAL D N   1 
ATOM   844  C  CA  . VAL A 1 105 ? -32.182 -7.281  48.649  1   49.88  ? 275 VAL D CA  1 
ATOM   845  C  C   . VAL A 1 105 ? -31.878 -8.267  49.769  1   50.55  ? 275 VAL D C   1 
ATOM   846  O  O   . VAL A 1 105 ? -31.68  -9.449  49.512  1   50.32  ? 275 VAL D O   1 
ATOM   847  C  CB  . VAL A 1 105 ? -30.894 -6.596  48.151  1   48.29  ? 275 VAL D CB  1 
ATOM   848  C  CG1 . VAL A 1 105 ? -29.885 -7.6    47.634  1   47.96  ? 275 VAL D CG1 1 
ATOM   849  C  CG2 . VAL A 1 105 ? -31.189 -5.591  47.052  1   48.64  ? 275 VAL D CG2 1 
ATOM   850  N  N   . ALA A 1 106 ? -31.852 -7.78   51.015  1   51.73  ? 276 ALA D N   1 
ATOM   851  C  CA  . ALA A 1 106 ? -31.47  -8.658  52.108  1   51.89  ? 276 ALA D CA  1 
ATOM   852  C  C   . ALA A 1 106 ? -32.4   -9.871  52.181  1   52.85  ? 276 ALA D C   1 
ATOM   853  O  O   . ALA A 1 106 ? -31.949 -10.946 52.566  1   55.49  ? 276 ALA D O   1 
ATOM   854  C  CB  . ALA A 1 106 ? -31.376 -7.915  53.41   1   49.09  ? 276 ALA D CB  1 
ATOM   855  N  N   . GLU A 1 107 ? -33.675 -9.701  51.808  1   51.67  ? 277 GLU D N   1 
ATOM   856  C  CA  . GLU A 1 107 ? -34.605 -10.813 51.895  1   56.98  ? 277 GLU D CA  1 
ATOM   857  C  C   . GLU A 1 107 ? -34.365 -11.799 50.758  1   57.54  ? 277 GLU D C   1 
ATOM   858  O  O   . GLU A 1 107 ? -34.609 -12.995 50.885  1   61.67  ? 277 GLU D O   1 
ATOM   859  C  CB  . GLU A 1 107 ? -36.04  -10.335 52.058  1   62.96  ? 277 GLU D CB  1 
ATOM   860  C  CG  . GLU A 1 107 ? -36.409 -10.288 53.54   1   77.7   ? 277 GLU D CG  1 
ATOM   861  C  CD  . GLU A 1 107 ? -37.284 -9.122  53.956  1   93.52  ? 277 GLU D CD  1 
ATOM   862  O  OE1 . GLU A 1 107 ? -37.598 -9.072  55.17   1   112.28 ? 277 GLU D OE1 1 
ATOM   863  O  OE2 . GLU A 1 107 ? -37.663 -8.291  53.087  1   96.37  ? 277 GLU D OE2 1 
ATOM   864  N  N   . PHE A 1 108 ? -33.829 -11.293 49.655  1   54.8   ? 278 PHE D N   1 
ATOM   865  C  CA  . PHE A 1 108 ? -33.481 -12.166 48.561  1   53.35  ? 278 PHE D CA  1 
ATOM   866  C  C   . PHE A 1 108 ? -32.271 -13.009 48.94   1   55.72  ? 278 PHE D C   1 
ATOM   867  O  O   . PHE A 1 108 ? -32.149 -14.138 48.462  1   58.38  ? 278 PHE D O   1 
ATOM   868  C  CB  . PHE A 1 108 ? -33.311 -11.347 47.287  1   50.41  ? 278 PHE D CB  1 
ATOM   869  C  CG  . PHE A 1 108 ? -34.659 -10.965 46.715  1   50.58  ? 278 PHE D CG  1 
ATOM   870  C  CD1 . PHE A 1 108 ? -35.378 -11.882 45.943  1   49.77  ? 278 PHE D CD1 1 
ATOM   871  C  CD2 . PHE A 1 108 ? -35.206 -9.708  46.973  1   51.8   ? 278 PHE D CD2 1 
ATOM   872  C  CE1 . PHE A 1 108 ? -36.614 -11.542 45.411  1   49.5   ? 278 PHE D CE1 1 
ATOM   873  C  CE2 . PHE A 1 108 ? -36.449 -9.367  46.44   1   54.72  ? 278 PHE D CE2 1 
ATOM   874  C  CZ  . PHE A 1 108 ? -37.15  -10.289 45.666  1   53.88  ? 278 PHE D CZ  1 
ATOM   875  N  N   . VAL A 1 109 ? -31.4   -12.457 49.796  1   54.9   ? 279 VAL D N   1 
ATOM   876  C  CA  . VAL A 1 109 ? -30.231 -13.197 50.259  1   56.62  ? 279 VAL D CA  1 
ATOM   877  C  C   . VAL A 1 109 ? -30.644 -14.224 51.318  1   60.6   ? 279 VAL D C   1 
ATOM   878  O  O   . VAL A 1 109 ? -30.069 -15.314 51.381  1   63.07  ? 279 VAL D O   1 
ATOM   879  C  CB  . VAL A 1 109 ? -29.138 -12.273 50.825  1   54.42  ? 279 VAL D CB  1 
ATOM   880  C  CG1 . VAL A 1 109 ? -27.904 -13.065 51.228  1   51.18  ? 279 VAL D CG1 1 
ATOM   881  C  CG2 . VAL A 1 109 ? -28.754 -11.175 49.852  1   54.43  ? 279 VAL D CG2 1 
ATOM   882  N  N   . TYR A 1 110 ? -31.602 -13.843 52.17   1   60.46  ? 280 TYR D N   1 
ATOM   883  C  CA  . TYR A 1 110 ? -32.067 -14.687 53.251  1   65.16  ? 280 TYR D CA  1 
ATOM   884  C  C   . TYR A 1 110 ? -32.699 -15.962 52.682  1   65.88  ? 280 TYR D C   1 
ATOM   885  O  O   . TYR A 1 110 ? -32.509 -17.031 53.257  1   70.39  ? 280 TYR D O   1 
ATOM   886  C  CB  . TYR A 1 110 ? -32.949 -13.884 54.213  1   68.36  ? 280 TYR D CB  1 
ATOM   887  C  CG  . TYR A 1 110 ? -33.646 -14.731 55.274  1   80.01  ? 280 TYR D CG  1 
ATOM   888  C  CD1 . TYR A 1 110 ? -33.038 -15.036 56.492  1   83.94  ? 280 TYR D CD1 1 
ATOM   889  C  CD2 . TYR A 1 110 ? -34.917 -15.258 55.046  1   83.34  ? 280 TYR D CD2 1 
ATOM   890  C  CE1 . TYR A 1 110 ? -33.689 -15.814 57.442  1   86.1   ? 280 TYR D CE1 1 
ATOM   891  C  CE2 . TYR A 1 110 ? -35.571 -16.048 55.976  1   82.69  ? 280 TYR D CE2 1 
ATOM   892  C  CZ  . TYR A 1 110 ? -34.958 -16.32  57.184  1   86.25  ? 280 TYR D CZ  1 
ATOM   893  O  OH  . TYR A 1 110 ? -35.649 -17.11  58.063  1   90.02  ? 280 TYR D OH  1 
ATOM   894  N  N   . ILE A 1 111 ? -33.423 -15.869 51.555  1   61.47  ? 281 ILE D N   1 
ATOM   895  C  CA  . ILE A 1 111 ? -34.147 -17.024 51.033  1   65.68  ? 281 ILE D CA  1 
ATOM   896  C  C   . ILE A 1 111 ? -33.214 -18.048 50.384  1   68.35  ? 281 ILE D C   1 
ATOM   897  O  O   . ILE A 1 111 ? -33.632 -19.178 50.129  1   70.89  ? 281 ILE D O   1 
ATOM   898  C  CB  . ILE A 1 111 ? -35.28  -16.645 50.058  1   66.83  ? 281 ILE D CB  1 
ATOM   899  C  CG1 . ILE A 1 111 ? -34.789 -15.689 48.972  1   65.73  ? 281 ILE D CG1 1 
ATOM   900  C  CG2 . ILE A 1 111 ? -36.492 -16.104 50.813  1   69.23  ? 281 ILE D CG2 1 
ATOM   901  C  CD1 . ILE A 1 111 ? -35.84  -15.322 47.944  1   65.05  ? 281 ILE D CD1 1 
ATOM   902  N  N   . THR A 1 112 ? -31.979 -17.649 50.067  1   66.43  ? 282 THR D N   1 
ATOM   903  C  CA  . THR A 1 112 ? -31.038 -18.59  49.485  1   67.73  ? 282 THR D CA  1 
ATOM   904  C  C   . THR A 1 112 ? -30.3   -19.355 50.575  1   71.2   ? 282 THR D C   1 
ATOM   905  O  O   . THR A 1 112 ? -29.406 -20.126 50.236  1   72.53  ? 282 THR D O   1 
ATOM   906  C  CB  . THR A 1 112 ? -30.044 -17.897 48.557  1   65.6   ? 282 THR D CB  1 
ATOM   907  O  OG1 . THR A 1 112 ? -29.509 -16.783 49.263  1   70.42  ? 282 THR D OG1 1 
ATOM   908  C  CG2 . THR A 1 112 ? -30.692 -17.428 47.274  1   59.53  ? 282 THR D CG2 1 
ATOM   909  N  N   . ASP A 1 113 ? -30.661 -19.112 51.851  1   78.24  ? 283 ASP D N   1 
ATOM   910  C  CA  . ASP A 1 113 ? -30.034 -19.715 53.026  1   85.83  ? 283 ASP D CA  1 
ATOM   911  C  C   . ASP A 1 113 ? -28.542 -19.4   53.106  1   84.69  ? 283 ASP D C   1 
ATOM   912  O  O   . ASP A 1 113 ? -27.758 -20.244 53.553  1   81.83  ? 283 ASP D O   1 
ATOM   913  C  CB  . ASP A 1 113 ? -30.232 -21.222 53.069  1   93.84  ? 283 ASP D CB  1 
ATOM   914  C  CG  . ASP A 1 113 ? -31.483 -21.679 53.794  1   100.49 ? 283 ASP D CG  1 
ATOM   915  O  OD1 . ASP A 1 113 ? -32.526 -20.988 53.664  1   99.89  ? 283 ASP D OD1 1 
ATOM   916  O  OD2 . ASP A 1 113 ? -31.389 -22.725 54.466  1   109.25 ? 283 ASP D OD2 1 
ATOM   917  N  N   . ASP A 1 114 ? -28.171 -18.181 52.688  1   86.32  ? 284 ASP D N   1 
ATOM   918  C  CA  . ASP A 1 114 ? -26.777 -17.78  52.55   1   95.78  ? 284 ASP D CA  1 
ATOM   919  C  C   . ASP A 1 114 ? -25.97  -18.821 51.757  1   88.46  ? 284 ASP D C   1 
ATOM   920  O  O   . ASP A 1 114 ? -24.82  -19.124 52.083  1   86.11  ? 284 ASP D O   1 
ATOM   921  C  CB  . ASP A 1 114 ? -26.186 -17.381 53.897  1   113.65 ? 284 ASP D CB  1 
ATOM   922  C  CG  . ASP A 1 114 ? -27.071 -16.503 54.774  1   117.22 ? 284 ASP D CG  1 
ATOM   923  O  OD1 . ASP A 1 114 ? -27.654 -15.535 54.232  1   117.41 ? 284 ASP D OD1 1 
ATOM   924  O  OD2 . ASP A 1 114 ? -27.164 -16.792 55.994  1   115.52 ? 284 ASP D OD2 1 
ATOM   925  N  N   . THR A 1 115 ? -26.57  -19.363 50.689  1   82.22  ? 285 THR D N   1 
ATOM   926  C  CA  . THR A 1 115 ? -25.785 -20.049 49.673  1   81.18  ? 285 THR D CA  1 
ATOM   927  C  C   . THR A 1 115 ? -24.919 -18.998 48.966  1   72.94  ? 285 THR D C   1 
ATOM   928  O  O   . THR A 1 115 ? -23.804 -19.294 48.568  1   72.55  ? 285 THR D O   1 
ATOM   929  C  CB  . THR A 1 115 ? -26.659 -20.843 48.688  1   85.15  ? 285 THR D CB  1 
ATOM   930  O  OG1 . THR A 1 115 ? -27.608 -21.668 49.358  1   84.19  ? 285 THR D OG1 1 
ATOM   931  C  CG2 . THR A 1 115 ? -25.858 -21.781 47.802  1   83.08  ? 285 THR D CG2 1 
ATOM   932  N  N   . TYR A 1 116 ? -25.439 -17.769 48.828  1   63.53  ? 286 TYR D N   1 
ATOM   933  C  CA  . TYR A 1 116 ? -24.787 -16.705 48.083  1   59.04  ? 286 TYR D CA  1 
ATOM   934  C  C   . TYR A 1 116 ? -24.721 -15.45  48.946  1   60.63  ? 286 TYR D C   1 
ATOM   935  O  O   . TYR A 1 116 ? -25.552 -15.277 49.827  1   66.16  ? 286 TYR D O   1 
ATOM   936  C  CB  . TYR A 1 116 ? -25.609 -16.384 46.833  1   54.6   ? 286 TYR D CB  1 
ATOM   937  C  CG  . TYR A 1 116 ? -25.896 -17.57  45.92   1   57.07  ? 286 TYR D CG  1 
ATOM   938  C  CD1 . TYR A 1 116 ? -24.856 -18.28  45.303  1   61.41  ? 286 TYR D CD1 1 
ATOM   939  C  CD2 . TYR A 1 116 ? -27.199 -17.97  45.637  1   54.09  ? 286 TYR D CD2 1 
ATOM   940  C  CE1 . TYR A 1 116 ? -25.102 -19.358 44.46   1   56.48  ? 286 TYR D CE1 1 
ATOM   941  C  CE2 . TYR A 1 116 ? -27.457 -19.043 44.791  1   53.72  ? 286 TYR D CE2 1 
ATOM   942  C  CZ  . TYR A 1 116 ? -26.411 -19.739 44.195  1   55.46  ? 286 TYR D CZ  1 
ATOM   943  O  OH  . TYR A 1 116 ? -26.669 -20.78  43.331  1   53.07  ? 286 TYR D OH  1 
ATOM   944  N  N   . THR A 1 117 ? -23.713 -14.6   48.703  1   58.82  ? 287 THR D N   1 
ATOM   945  C  CA  . THR A 1 117 ? -23.52  -13.338 49.402  1   61.92  ? 287 THR D CA  1 
ATOM   946  C  C   . THR A 1 117 ? -24.4   -12.257 48.777  1   59.67  ? 287 THR D C   1 
ATOM   947  O  O   . THR A 1 117 ? -24.939 -12.429 47.687  1   59.57  ? 287 THR D O   1 
ATOM   948  C  CB  . THR A 1 117 ? -22.039 -12.936 49.498  1   65.9   ? 287 THR D CB  1 
ATOM   949  O  OG1 . THR A 1 117 ? -21.976 -11.621 50.058  1   78.94  ? 287 THR D OG1 1 
ATOM   950  C  CG2 . THR A 1 117 ? -21.317 -12.87  48.166  1   61.62  ? 287 THR D CG2 1 
ATOM   951  N  N   . LYS A 1 118 ? -24.532 -11.132 49.483  1   60.68  ? 288 LYS D N   1 
ATOM   952  C  CA  . LYS A 1 118 ? -25.292 -10.007 48.966  1   61.18  ? 288 LYS D CA  1 
ATOM   953  C  C   . LYS A 1 118 ? -24.612 -9.462  47.699  1   62.54  ? 288 LYS D C   1 
ATOM   954  O  O   . LYS A 1 118 ? -25.303 -9.114  46.738  1   61.01  ? 288 LYS D O   1 
ATOM   955  C  CB  . LYS A 1 118 ? -25.549 -8.966  50.064  1   61.09  ? 288 LYS D CB  1 
ATOM   956  C  CG  . LYS A 1 118 ? -26.673 -8.008  49.691  1   60.06  ? 288 LYS D CG  1 
ATOM   957  C  CD  . LYS A 1 118 ? -26.62  -6.641  50.356  1   63.24  ? 288 LYS D CD  1 
ATOM   958  C  CE  . LYS A 1 118 ? -27.102 -6.591  51.76   1   68.4   ? 288 LYS D CE  1 
ATOM   959  N  NZ  . LYS A 1 118 ? -27.225 -5.2    52.205  1   71.88  ? 288 LYS D NZ  1 
ATOM   960  N  N   . LYS A 1 119 ? -23.264 -9.426  47.693  1   60.37  ? 289 LYS D N   1 
ATOM   961  C  CA  . LYS A 1 119 ? -22.466 -8.912  46.586  1   57.22  ? 289 LYS D CA  1 
ATOM   962  C  C   . LYS A 1 119 ? -22.756 -9.735  45.334  1   54.32  ? 289 LYS D C   1 
ATOM   963  O  O   . LYS A 1 119 ? -22.938 -9.186  44.248  1   56.05  ? 289 LYS D O   1 
ATOM   964  C  CB  . LYS A 1 119 ? -20.962 -8.928  46.908  1   64.36  ? 289 LYS D CB  1 
ATOM   965  C  CG  . LYS A 1 119 ? -20.043 -7.969  46.159  1   72.01  ? 289 LYS D CG  1 
ATOM   966  C  CD  . LYS A 1 119 ? -20.657 -6.581  45.938  1   85.35  ? 289 LYS D CD  1 
ATOM   967  C  CE  . LYS A 1 119 ? -19.826 -5.458  45.327  1   87.6   ? 289 LYS D CE  1 
ATOM   968  N  NZ  . LYS A 1 119 ? -18.916 -4.78   46.264  1   81.14  ? 289 LYS D NZ  1 
ATOM   969  N  N   . GLN A 1 120 ? -22.859 -11.056 45.497  1   52.01  ? 290 GLN D N   1 
ATOM   970  C  CA  . GLN A 1 120 ? -23.146 -11.947 44.387  1   49.35  ? 290 GLN D CA  1 
ATOM   971  C  C   . GLN A 1 120 ? -24.545 -11.67  43.846  1   47.29  ? 290 GLN D C   1 
ATOM   972  O  O   . GLN A 1 120 ? -24.712 -11.486 42.65   1   44.17  ? 290 GLN D O   1 
ATOM   973  C  CB  . GLN A 1 120 ? -23.012 -13.406 44.803  1   52.22  ? 290 GLN D CB  1 
ATOM   974  C  CG  . GLN A 1 120 ? -21.567 -13.866 44.956  1   57.2   ? 290 GLN D CG  1 
ATOM   975  C  CD  . GLN A 1 120 ? -21.467 -15.289 45.46   1   62.16  ? 290 GLN D CD  1 
ATOM   976  O  OE1 . GLN A 1 120 ? -21.82  -15.57  46.604  1   63.62  ? 290 GLN D OE1 1 
ATOM   977  N  NE2 . GLN A 1 120 ? -21.044 -16.222 44.615  1   64.93  ? 290 GLN D NE2 1 
ATOM   978  N  N   . VAL A 1 121 ? -25.56  -11.658 44.714  1   47.21  ? 291 VAL D N   1 
ATOM   979  C  CA  . VAL A 1 121 ? -26.894 -11.33  44.242  1   45.66  ? 291 VAL D CA  1 
ATOM   980  C  C   . VAL A 1 121 ? -26.845 -10.032 43.43   1   44.17  ? 291 VAL D C   1 
ATOM   981  O  O   . VAL A 1 121 ? -27.335 -9.982  42.301  1   45.43  ? 291 VAL D O   1 
ATOM   982  C  CB  . VAL A 1 121 ? -27.905 -11.251 45.401  1   47.31  ? 291 VAL D CB  1 
ATOM   983  C  CG1 . VAL A 1 121 ? -29.246 -10.65  44.959  1   44.55  ? 291 VAL D CG1 1 
ATOM   984  C  CG2 . VAL A 1 121 ? -28.094 -12.601 46.066  1   45.3   ? 291 VAL D CG2 1 
ATOM   985  N  N   . LEU A 1 122 ? -26.218 -8.992  43.981  1   43.86  ? 292 LEU D N   1 
ATOM   986  C  CA  . LEU A 1 122 ? -26.289 -7.659  43.393  1   45.46  ? 292 LEU D CA  1 
ATOM   987  C  C   . LEU A 1 122 ? -25.519 -7.572  42.077  1   45.3   ? 292 LEU D C   1 
ATOM   988  O  O   . LEU A 1 122 ? -25.963 -6.899  41.129  1   43.66  ? 292 LEU D O   1 
ATOM   989  C  CB  . LEU A 1 122 ? -25.751 -6.65   44.405  1   46.51  ? 292 LEU D CB  1 
ATOM   990  C  CG  . LEU A 1 122 ? -26.737 -6.253  45.507  1   47.14  ? 292 LEU D CG  1 
ATOM   991  C  CD1 . LEU A 1 122 ? -26.031 -5.365  46.487  1   49.23  ? 292 LEU D CD1 1 
ATOM   992  C  CD2 . LEU A 1 122 ? -27.979 -5.578  44.952  1   44.74  ? 292 LEU D CD2 1 
ATOM   993  N  N   . ARG A 1 123 ? -24.367 -8.255  42.049  1   43.44  ? 293 ARG D N   1 
ATOM   994  C  CA  . ARG A 1 123 ? -23.59  -8.41   40.832  1   44.96  ? 293 ARG D CA  1 
ATOM   995  C  C   . ARG A 1 123 ? -24.359 -9.2    39.769  1   41.67  ? 293 ARG D C   1 
ATOM   996  O  O   . ARG A 1 123 ? -24.293 -8.882  38.59   1   42.36  ? 293 ARG D O   1 
ATOM   997  C  CB  . ARG A 1 123 ? -22.238 -9.056  41.15   1   48.72  ? 293 ARG D CB  1 
ATOM   998  C  CG  . ARG A 1 123 ? -21.215 -8.063  41.677  1   53.43  ? 293 ARG D CG  1 
ATOM   999  C  CD  . ARG A 1 123 ? -19.92  -8.289  40.906  1   69.84  ? 293 ARG D CD  1 
ATOM   1000 N  NE  . ARG A 1 123 ? -18.895 -7.372  41.413  1   91.49  ? 293 ARG D NE  1 
ATOM   1001 C  CZ  . ARG A 1 123 ? -18     -7.746  42.331  1   108.68 ? 293 ARG D CZ  1 
ATOM   1002 N  NH1 . ARG A 1 123 ? -17.203 -6.862  42.925  1   101.06 ? 293 ARG D NH1 1 
ATOM   1003 N  NH2 . ARG A 1 123 ? -17.948 -9.02   42.69   1   115.99 ? 293 ARG D NH2 1 
ATOM   1004 N  N   . MET A 1 124 ? -25.052 -10.268 40.172  1   42.84  ? 294 MET D N   1 
ATOM   1005 C  CA  . MET A 1 124 ? -25.805 -11.072 39.226  1   40.85  ? 294 MET D CA  1 
ATOM   1006 C  C   . MET A 1 124 ? -26.971 -10.245 38.706  1   39.01  ? 294 MET D C   1 
ATOM   1007 O  O   . MET A 1 124 ? -27.332 -10.355 37.54   1   37.99  ? 294 MET D O   1 
ATOM   1008 C  CB  . MET A 1 124 ? -26.359 -12.349 39.847  1   40.21  ? 294 MET D CB  1 
ATOM   1009 C  CG  . MET A 1 124 ? -27.208 -13.126 38.858  1   41.07  ? 294 MET D CG  1 
ATOM   1010 S  SD  . MET A 1 124 ? -26.342 -13.786 37.415  1   42.11  ? 294 MET D SD  1 
ATOM   1011 C  CE  . MET A 1 124 ? -25.548 -15.23  38.131  1   39.43  ? 294 MET D CE  1 
ATOM   1012 N  N   . GLU A 1 125 ? -27.522 -9.38   39.56   1   40.03  ? 295 GLU D N   1 
ATOM   1013 C  CA  . GLU A 1 125 ? -28.551 -8.439  39.12   1   42.01  ? 295 GLU D CA  1 
ATOM   1014 C  C   . GLU A 1 125 ? -28.054 -7.67   37.901  1   41.53  ? 295 GLU D C   1 
ATOM   1015 O  O   . GLU A 1 125 ? -28.743 -7.608  36.89   1   42.54  ? 295 GLU D O   1 
ATOM   1016 C  CB  . GLU A 1 125 ? -28.993 -7.458  40.211  1   40.67  ? 295 GLU D CB  1 
ATOM   1017 C  CG  . GLU A 1 125 ? -30.197 -6.595  39.825  1   37.9   ? 295 GLU D CG  1 
ATOM   1018 C  CD  . GLU A 1 125 ? -30.55  -5.5    40.834  1   41.75  ? 295 GLU D CD  1 
ATOM   1019 O  OE1 . GLU A 1 125 ? -29.662 -4.645  41.095  1   44.72  ? 295 GLU D OE1 1 
ATOM   1020 O  OE2 . GLU A 1 125 ? -31.679 -5.486  41.403  1   39.95  ? 295 GLU D OE2 1 
ATOM   1021 N  N   . HIS A 1 126 ? -26.864 -7.081  38.024  1   42.69  ? 296 HIS D N   1 
ATOM   1022 C  CA  . HIS A 1 126 ? -26.34  -6.207  36.988  1   44.05  ? 296 HIS D CA  1 
ATOM   1023 C  C   . HIS A 1 126 ? -26.119 -7.039  35.732  1   43.24  ? 296 HIS D C   1 
ATOM   1024 O  O   . HIS A 1 126 ? -26.465 -6.59   34.651  1   44.63  ? 296 HIS D O   1 
ATOM   1025 C  CB  . HIS A 1 126 ? -25.054 -5.489  37.434  1   46.19  ? 296 HIS D CB  1 
ATOM   1026 C  CG  . HIS A 1 126 ? -24.688 -4.26   36.657  1   50.51  ? 296 HIS D CG  1 
ATOM   1027 N  ND1 . HIS A 1 126 ? -23.623 -3.456  37.013  1   53.6   ? 296 HIS D ND1 1 
ATOM   1028 C  CD2 . HIS A 1 126 ? -25.205 -3.709  35.543  1   51.2   ? 296 HIS D CD2 1 
ATOM   1029 C  CE1 . HIS A 1 126 ? -23.495 -2.48   36.12   1   54.46  ? 296 HIS D CE1 1 
ATOM   1030 N  NE2 . HIS A 1 126 ? -24.471 -2.586  35.242  1   53.19  ? 296 HIS D NE2 1 
ATOM   1031 N  N   . LEU A 1 127 ? -25.559 -8.244  35.882  1   41.92  ? 297 LEU D N   1 
ATOM   1032 C  CA  . LEU A 1 127 ? -25.299 -9.107  34.739  1   40.52  ? 297 LEU D CA  1 
ATOM   1033 C  C   . LEU A 1 127 ? -26.602 -9.467  34.03   1   40.75  ? 297 LEU D C   1 
ATOM   1034 O  O   . LEU A 1 127 ? -26.657 -9.503  32.807  1   44     ? 297 LEU D O   1 
ATOM   1035 C  CB  . LEU A 1 127 ? -24.544 -10.372 35.136  1   39.54  ? 297 LEU D CB  1 
ATOM   1036 C  CG  . LEU A 1 127 ? -24.125 -11.26  33.958  1   38.31  ? 297 LEU D CG  1 
ATOM   1037 C  CD1 . LEU A 1 127 ? -23.102 -10.6   33.038  1   35.92  ? 297 LEU D CD1 1 
ATOM   1038 C  CD2 . LEU A 1 127 ? -23.64  -12.618 34.439  1   38.38  ? 297 LEU D CD2 1 
ATOM   1039 N  N   . VAL A 1 128 ? -27.655 -9.75   34.796  1   40.94  ? 298 VAL D N   1 
ATOM   1040 C  CA  . VAL A 1 128 ? -28.904 -10.109 34.151  1   42.01  ? 298 VAL D CA  1 
ATOM   1041 C  C   . VAL A 1 128 ? -29.409 -8.938  33.303  1   44.75  ? 298 VAL D C   1 
ATOM   1042 O  O   . VAL A 1 128 ? -29.889 -9.162  32.183  1   48.69  ? 298 VAL D O   1 
ATOM   1043 C  CB  . VAL A 1 128 ? -29.951 -10.635 35.141  1   39.58  ? 298 VAL D CB  1 
ATOM   1044 C  CG1 . VAL A 1 128 ? -31.318 -10.727 34.475  1   38.46  ? 298 VAL D CG1 1 
ATOM   1045 C  CG2 . VAL A 1 128 ? -29.52  -11.981 35.721  1   35.49  ? 298 VAL D CG2 1 
ATOM   1046 N  N   . LEU A 1 129 ? -29.251 -7.706  33.816  1   42.49  ? 299 LEU D N   1 
ATOM   1047 C  CA  . LEU A 1 129 ? -29.69  -6.505  33.118  1   42.7   ? 299 LEU D CA  1 
ATOM   1048 C  C   . LEU A 1 129 ? -28.928 -6.316  31.809  1   46.07  ? 299 LEU D C   1 
ATOM   1049 O  O   . LEU A 1 129 ? -29.52  -5.954  30.784  1   49.61  ? 299 LEU D O   1 
ATOM   1050 C  CB  . LEU A 1 129 ? -29.614 -5.274  34.016  1   43.03  ? 299 LEU D CB  1 
ATOM   1051 C  CG  . LEU A 1 129 ? -30.735 -5.136  35.065  1   44.5   ? 299 LEU D CG  1 
ATOM   1052 C  CD1 . LEU A 1 129 ? -30.352 -4.133  36.144  1   39.7   ? 299 LEU D CD1 1 
ATOM   1053 C  CD2 . LEU A 1 129 ? -32.093 -4.756  34.436  1   42.04  ? 299 LEU D CD2 1 
ATOM   1054 N  N   . LYS A 1 130 ? -27.622 -6.596  31.839  1   44.74  ? 300 LYS D N   1 
ATOM   1055 C  CA  . LYS A 1 130 ? -26.777 -6.39   30.669  1   47.66  ? 300 LYS D CA  1 
ATOM   1056 C  C   . LYS A 1 130 ? -27.121 -7.418  29.587  1   47.96  ? 300 LYS D C   1 
ATOM   1057 O  O   . LYS A 1 130 ? -27.221 -7.065  28.404  1   46.13  ? 300 LYS D O   1 
ATOM   1058 C  CB  . LYS A 1 130 ? -25.283 -6.484  31.01   1   47.22  ? 300 LYS D CB  1 
ATOM   1059 C  CG  . LYS A 1 130 ? -24.683 -5.282  31.694  1   49.41  ? 300 LYS D CG  1 
ATOM   1060 C  CD  . LYS A 1 130 ? -23.346 -5.591  32.362  1   57.09  ? 300 LYS D CD  1 
ATOM   1061 C  CE  . LYS A 1 130 ? -22.629 -4.341  32.822  1   67.76  ? 300 LYS D CE  1 
ATOM   1062 N  NZ  . LYS A 1 130 ? -21.388 -4.605  33.561  1   75.63  ? 300 LYS D NZ  1 
ATOM   1063 N  N   . VAL A 1 131 ? -27.29  -8.681  30.011  1   43.51  ? 301 VAL D N   1 
ATOM   1064 C  CA  . VAL A 1 131 ? -27.627 -9.748  29.095  1   45.9   ? 301 VAL D CA  1 
ATOM   1065 C  C   . VAL A 1 131 ? -28.985 -9.502  28.433  1   49     ? 301 VAL D C   1 
ATOM   1066 O  O   . VAL A 1 131 ? -29.139 -9.826  27.27   1   48.58  ? 301 VAL D O   1 
ATOM   1067 C  CB  . VAL A 1 131 ? -27.59  -11.105 29.809  1   45.3   ? 301 VAL D CB  1 
ATOM   1068 C  CG1 . VAL A 1 131 ? -28.434 -12.183 29.095  1   41.1   ? 301 VAL D CG1 1 
ATOM   1069 C  CG2 . VAL A 1 131 ? -26.144 -11.522 30.027  1   42.13  ? 301 VAL D CG2 1 
ATOM   1070 N  N   . LEU A 1 132 ? -29.97  -8.976  29.173  1   51.85  ? 302 LEU D N   1 
ATOM   1071 C  CA  . LEU A 1 132 ? -31.303 -8.721  28.637  1   48.96  ? 302 LEU D CA  1 
ATOM   1072 C  C   . LEU A 1 132 ? -31.358 -7.321  28.044  1   48.9   ? 302 LEU D C   1 
ATOM   1073 O  O   . LEU A 1 132 ? -32.402 -6.912  27.548  1   49.41  ? 302 LEU D O   1 
ATOM   1074 C  CB  . LEU A 1 132 ? -32.346 -8.844  29.746  1   50.37  ? 302 LEU D CB  1 
ATOM   1075 C  CG  . LEU A 1 132 ? -32.408 -10.192 30.461  1   51.03  ? 302 LEU D CG  1 
ATOM   1076 C  CD1 . LEU A 1 132 ? -33.538 -10.18  31.463  1   52.86  ? 302 LEU D CD1 1 
ATOM   1077 C  CD2 . LEU A 1 132 ? -32.642 -11.288 29.442  1   51.17  ? 302 LEU D CD2 1 
ATOM   1078 N  N   . ALA A 1 133 ? -30.247 -6.579  28.144  1   49.66  ? 303 ALA D N   1 
ATOM   1079 C  CA  . ALA A 1 133 ? -30.17  -5.223  27.618  1   49.34  ? 303 ALA D CA  1 
ATOM   1080 C  C   . ALA A 1 133 ? -31.303 -4.367  28.181  1   51.09  ? 303 ALA D C   1 
ATOM   1081 O  O   . ALA A 1 133 ? -31.829 -3.548  27.43   1   49.8   ? 303 ALA D O   1 
ATOM   1082 C  CB  . ALA A 1 133 ? -30.236 -5.256  26.107  1   44.9   ? 303 ALA D CB  1 
ATOM   1083 N  N   . PHE A 1 134 ? -31.686 -4.605  29.462  1   47.28  ? 304 PHE D N   1 
ATOM   1084 C  CA  . PHE A 1 134 ? -32.747 -3.894  30.169  1   47.34  ? 304 PHE D CA  1 
ATOM   1085 C  C   . PHE A 1 134 ? -34.147 -4.074  29.57   1   50.54  ? 304 PHE D C   1 
ATOM   1086 O  O   . PHE A 1 134 ? -35.021 -3.274  29.87   1   51.99  ? 304 PHE D O   1 
ATOM   1087 C  CB  . PHE A 1 134 ? -32.432 -2.398  30.211  1   49.34  ? 304 PHE D CB  1 
ATOM   1088 C  CG  . PHE A 1 134 ? -31.554 -1.972  31.375  1   53.3   ? 304 PHE D CG  1 
ATOM   1089 C  CD1 . PHE A 1 134 ? -32.133 -1.664  32.606  1   49.91  ? 304 PHE D CD1 1 
ATOM   1090 C  CD2 . PHE A 1 134 ? -30.167 -1.867  31.233  1   52.12  ? 304 PHE D CD2 1 
ATOM   1091 C  CE1 . PHE A 1 134 ? -31.337 -1.277  33.668  1   50.36  ? 304 PHE D CE1 1 
ATOM   1092 C  CE2 . PHE A 1 134 ? -29.375 -1.477  32.307  1   52.05  ? 304 PHE D CE2 1 
ATOM   1093 C  CZ  . PHE A 1 134 ? -29.962 -1.183  33.519  1   51.3   ? 304 PHE D CZ  1 
ATOM   1094 N  N   . ASP A 1 135 ? -34.401 -5.095  28.728  1   56.63  ? 305 ASP D N   1 
ATOM   1095 C  CA  . ASP A 1 135 ? -35.746 -5.336  28.2    1   55.82  ? 305 ASP D CA  1 
ATOM   1096 C  C   . ASP A 1 135 ? -36.591 -6.122  29.195  1   53.99  ? 305 ASP D C   1 
ATOM   1097 O  O   . ASP A 1 135 ? -36.689 -7.351  29.062  1   53.37  ? 305 ASP D O   1 
ATOM   1098 C  CB  . ASP A 1 135 ? -35.742 -6.224  26.971  1   58.32  ? 305 ASP D CB  1 
ATOM   1099 C  CG  . ASP A 1 135 ? -35.622 -5.507  25.64   1   74.31  ? 305 ASP D CG  1 
ATOM   1100 O  OD1 . ASP A 1 135 ? -34.717 -4.632  25.515  1   72.64  ? 305 ASP D OD1 1 
ATOM   1101 O  OD2 . ASP A 1 135 ? -36.431 -5.859  24.75   1   84.44  ? 305 ASP D OD2 1 
ATOM   1102 N  N   . LEU A 1 136 ? -37.222 -5.433  30.164  1   48.41  ? 306 LEU D N   1 
ATOM   1103 C  CA  . LEU A 1 136 ? -37.883 -6.187  31.211  1   47.4   ? 306 LEU D CA  1 
ATOM   1104 C  C   . LEU A 1 136 ? -39.394 -6.256  30.997  1   48.56  ? 306 LEU D C   1 
ATOM   1105 O  O   . LEU A 1 136 ? -40.063 -7.046  31.663  1   50.68  ? 306 LEU D O   1 
ATOM   1106 C  CB  . LEU A 1 136 ? -37.49  -5.647  32.582  1   48.99  ? 306 LEU D CB  1 
ATOM   1107 C  CG  . LEU A 1 136 ? -35.988 -5.613  32.902  1   50.51  ? 306 LEU D CG  1 
ATOM   1108 C  CD1 . LEU A 1 136 ? -35.814 -5.45   34.388  1   53.09  ? 306 LEU D CD1 1 
ATOM   1109 C  CD2 . LEU A 1 136 ? -35.158 -6.81   32.46   1   48.62  ? 306 LEU D CD2 1 
ATOM   1110 N  N   . ALA A 1 137 ? -39.921 -5.471  30.044  1   47.82  ? 307 ALA D N   1 
ATOM   1111 C  CA  . ALA A 1 137 ? -41.364 -5.332  29.889  1   49.01  ? 307 ALA D CA  1 
ATOM   1112 C  C   . ALA A 1 137 ? -41.92  -6.433  28.995  1   48.4   ? 307 ALA D C   1 
ATOM   1113 O  O   . ALA A 1 137 ? -42.476 -6.16   27.933  1   52.41  ? 307 ALA D O   1 
ATOM   1114 C  CB  . ALA A 1 137 ? -41.717 -3.943  29.38   1   48.39  ? 307 ALA D CB  1 
ATOM   1115 N  N   . ALA A 1 138 ? -41.805 -7.67   29.474  1   46.63  ? 308 ALA D N   1 
ATOM   1116 C  CA  . ALA A 1 138 ? -42.188 -8.842  28.703  1   47.71  ? 308 ALA D CA  1 
ATOM   1117 C  C   . ALA A 1 138 ? -43.671 -9.132  28.89   1   52.14  ? 308 ALA D C   1 
ATOM   1118 O  O   . ALA A 1 138 ? -44.202 -9.164  29.993  1   56.58  ? 308 ALA D O   1 
ATOM   1119 C  CB  . ALA A 1 138 ? -41.344 -10.022 29.121  1   43.53  ? 308 ALA D CB  1 
ATOM   1120 N  N   . PRO A 1 139 ? -44.421 -9.369  27.814  1   54.94  ? 309 PRO D N   1 
ATOM   1121 C  CA  . PRO A 1 139 ? -45.785 -9.852  27.98   1   58.23  ? 309 PRO D CA  1 
ATOM   1122 C  C   . PRO A 1 139 ? -45.666 -11.237 28.611  1   58.63  ? 309 PRO D C   1 
ATOM   1123 O  O   . PRO A 1 139 ? -44.718 -11.971 28.309  1   60.16  ? 309 PRO D O   1 
ATOM   1124 C  CB  . PRO A 1 139 ? -46.382 -9.851  26.557  1   58.87  ? 309 PRO D CB  1 
ATOM   1125 C  CG  . PRO A 1 139 ? -45.373 -9.086  25.706  1   58.79  ? 309 PRO D CG  1 
ATOM   1126 C  CD  . PRO A 1 139 ? -44.02  -9.188  26.417  1   57.77  ? 309 PRO D CD  1 
ATOM   1127 N  N   . THR A 1 140 ? -46.646 -11.55  29.481  1   58     ? 310 THR D N   1 
ATOM   1128 C  CA  . THR A 1 140 ? -46.732 -12.773 30.271  1   55.64  ? 310 THR D CA  1 
ATOM   1129 C  C   . THR A 1 140 ? -48.018 -13.504 29.935  1   59.42  ? 310 THR D C   1 
ATOM   1130 O  O   . THR A 1 140 ? -48.95  -12.899 29.402  1   61.76  ? 310 THR D O   1 
ATOM   1131 C  CB  . THR A 1 140 ? -46.737 -12.459 31.77   1   52.42  ? 310 THR D CB  1 
ATOM   1132 O  OG1 . THR A 1 140 ? -47.823 -11.589 32.061  1   50.54  ? 310 THR D OG1 1 
ATOM   1133 C  CG2 . THR A 1 140 ? -45.457 -11.798 32.246  1   50.71  ? 310 THR D CG2 1 
ATOM   1134 N  N   . ILE A 1 141 ? -48.1   -14.774 30.36   1   61.58  ? 311 ILE D N   1 
ATOM   1135 C  CA  . ILE A 1 141 ? -49.365 -15.49  30.252  1   62.6   ? 311 ILE D CA  1 
ATOM   1136 C  C   . ILE A 1 141 ? -50.478 -14.679 30.922  1   66.61  ? 311 ILE D C   1 
ATOM   1137 O  O   . ILE A 1 141 ? -51.597 -14.615 30.406  1   70.89  ? 311 ILE D O   1 
ATOM   1138 C  CB  . ILE A 1 141 ? -49.261 -16.912 30.825  1   60.18  ? 311 ILE D CB  1 
ATOM   1139 C  CG1 . ILE A 1 141 ? -48.491 -17.842 29.884  1   60.12  ? 311 ILE D CG1 1 
ATOM   1140 C  CG2 . ILE A 1 141 ? -50.649 -17.46  31.147  1   60.39  ? 311 ILE D CG2 1 
ATOM   1141 C  CD1 . ILE A 1 141 ? -47.85  -19.041 30.58   1   59.69  ? 311 ILE D CD1 1 
ATOM   1142 N  N   . ASN A 1 142 ? -50.161 -14.043 32.059  1   64.8   ? 312 ASN D N   1 
ATOM   1143 C  CA  . ASN A 1 142 ? -51.189 -13.38  32.841  1   68.88  ? 312 ASN D CA  1 
ATOM   1144 C  C   . ASN A 1 142 ? -51.711 -12.148 32.111  1   68.58  ? 312 ASN D C   1 
ATOM   1145 O  O   . ASN A 1 142 ? -52.888 -11.831 32.239  1   73.2   ? 312 ASN D O   1 
ATOM   1146 C  CB  . ASN A 1 142 ? -50.75  -13.074 34.267  1   71.35  ? 312 ASN D CB  1 
ATOM   1147 C  CG  . ASN A 1 142 ? -50.805 -14.285 35.168  1   81.63  ? 312 ASN D CG  1 
ATOM   1148 O  OD1 . ASN A 1 142 ? -50.745 -15.432 34.699  1   94.08  ? 312 ASN D OD1 1 
ATOM   1149 N  ND2 . ASN A 1 142 ? -50.892 -14.048 36.467  1   82.47  ? 312 ASN D ND2 1 
ATOM   1150 N  N   . GLN A 1 143 ? -50.849 -11.459 31.357  1   64.87  ? 313 GLN D N   1 
ATOM   1151 C  CA  . GLN A 1 143 ? -51.267 -10.221 30.713  1   66.55  ? 313 GLN D CA  1 
ATOM   1152 C  C   . GLN A 1 143 ? -52.271 -10.511 29.61   1   71.35  ? 313 GLN D C   1 
ATOM   1153 O  O   . GLN A 1 143 ? -53.014 -9.623  29.196  1   79.63  ? 313 GLN D O   1 
ATOM   1154 C  CB  . GLN A 1 143 ? -50.12  -9.45   30.075  1   61.67  ? 313 GLN D CB  1 
ATOM   1155 C  CG  . GLN A 1 143 ? -49.274 -8.719  31.104  1   61.62  ? 313 GLN D CG  1 
ATOM   1156 C  CD  . GLN A 1 143 ? -48.171 -7.932  30.44   1   61.67  ? 313 GLN D CD  1 
ATOM   1157 O  OE1 . GLN A 1 143 ? -48.419 -7.105  29.547  1   66.15  ? 313 GLN D OE1 1 
ATOM   1158 N  NE2 . GLN A 1 143 ? -46.945 -8.215  30.854  1   53.83  ? 313 GLN D NE2 1 
ATOM   1159 N  N   . PHE A 1 144 ? -52.238 -11.745 29.102  1   68.16  ? 314 PHE D N   1 
ATOM   1160 C  CA  . PHE A 1 144 ? -53.197 -12.132 28.091  1   67.47  ? 314 PHE D CA  1 
ATOM   1161 C  C   . PHE A 1 144 ? -54.48  -12.586 28.778  1   70.76  ? 314 PHE D C   1 
ATOM   1162 O  O   . PHE A 1 144 ? -55.562 -12.153 28.376  1   71.57  ? 314 PHE D O   1 
ATOM   1163 C  CB  . PHE A 1 144 ? -52.575 -13.123 27.117  1   66.21  ? 314 PHE D CB  1 
ATOM   1164 C  CG  . PHE A 1 144 ? -51.646 -12.45  26.123  1   62.97  ? 314 PHE D CG  1 
ATOM   1165 C  CD1 . PHE A 1 144 ? -52.166 -11.655 25.1    1   63.79  ? 314 PHE D CD1 1 
ATOM   1166 C  CD2 . PHE A 1 144 ? -50.274 -12.636 26.206  1   57.89  ? 314 PHE D CD2 1 
ATOM   1167 C  CE1 . PHE A 1 144 ? -51.32  -11.051 24.183  1   62.75  ? 314 PHE D CE1 1 
ATOM   1168 C  CE2 . PHE A 1 144 ? -49.44  -12.031 25.291  1   58.05  ? 314 PHE D CE2 1 
ATOM   1169 C  CZ  . PHE A 1 144 ? -49.958 -11.236 24.289  1   60.45  ? 314 PHE D CZ  1 
ATOM   1170 N  N   . LEU A 1 145 ? -54.334 -13.385 29.848  1   69.72  ? 315 LEU D N   1 
ATOM   1171 C  CA  . LEU A 1 145 ? -55.464 -13.87  30.631  1   70.77  ? 315 LEU D CA  1 
ATOM   1172 C  C   . LEU A 1 145 ? -56.345 -12.723 31.126  1   73.61  ? 315 LEU D C   1 
ATOM   1173 O  O   . LEU A 1 145 ? -57.552 -12.78  30.93   1   80.2   ? 315 LEU D O   1 
ATOM   1174 C  CB  . LEU A 1 145 ? -55.008 -14.739 31.801  1   68.59  ? 315 LEU D CB  1 
ATOM   1175 C  CG  . LEU A 1 145 ? -54.492 -16.14  31.473  1   66.83  ? 315 LEU D CG  1 
ATOM   1176 C  CD1 . LEU A 1 145 ? -54.083 -16.814 32.772  1   67.72  ? 315 LEU D CD1 1 
ATOM   1177 C  CD2 . LEU A 1 145 ? -55.488 -16.983 30.737  1   66.85  ? 315 LEU D CD2 1 
ATOM   1178 N  N   . THR A 1 146 ? -55.771 -11.699 31.782  1   73.02  ? 316 THR D N   1 
ATOM   1179 C  CA  . THR A 1 146 ? -56.592 -10.678 32.431  1   74.26  ? 316 THR D CA  1 
ATOM   1180 C  C   . THR A 1 146 ? -57.469 -9.972  31.4    1   77.04  ? 316 THR D C   1 
ATOM   1181 O  O   . THR A 1 146 ? -58.591 -9.57   31.723  1   80.16  ? 316 THR D O   1 
ATOM   1182 C  CB  . THR A 1 146 ? -55.794 -9.715  33.318  1   72.05  ? 316 THR D CB  1 
ATOM   1183 O  OG1 . THR A 1 146 ? -54.816 -9.011  32.563  1   71.78  ? 316 THR D OG1 1 
ATOM   1184 C  CG2 . THR A 1 146 ? -55.084 -10.409 34.469  1   69.36  ? 316 THR D CG2 1 
ATOM   1185 N  N   . GLN A 1 147 ? -56.949 -9.864  30.163  1   77.16  ? 317 GLN D N   1 
ATOM   1186 C  CA  . GLN A 1 147 ? -57.669 -9.363  28.995  1   78.45  ? 317 GLN D CA  1 
ATOM   1187 C  C   . GLN A 1 147 ? -58.732 -10.364 28.542  1   83.51  ? 317 GLN D C   1 
ATOM   1188 O  O   . GLN A 1 147 ? -59.819 -9.964  28.119  1   87.51  ? 317 GLN D O   1 
ATOM   1189 C  CB  . GLN A 1 147 ? -56.745 -9.142  27.794  1   74.52  ? 317 GLN D CB  1 
ATOM   1190 C  CG  . GLN A 1 147 ? -55.961 -7.836  27.817  1   75.07  ? 317 GLN D CG  1 
ATOM   1191 C  CD  . GLN A 1 147 ? -55.08  -7.655  26.602  1   75.88  ? 317 GLN D CD  1 
ATOM   1192 O  OE1 . GLN A 1 147 ? -55.542 -7.503  25.464  1   80.54  ? 317 GLN D OE1 1 
ATOM   1193 N  NE2 . GLN A 1 147 ? -53.78  -7.7    26.838  1   76.6   ? 317 GLN D NE2 1 
ATOM   1194 N  N   . TYR A 1 148 ? -58.37  -11.658 28.541  1   81.82  ? 318 TYR D N   1 
ATOM   1195 C  CA  . TYR A 1 148 ? -59.246 -12.705 28.039  1   82.35  ? 318 TYR D CA  1 
ATOM   1196 C  C   . TYR A 1 148 ? -60.409 -12.896 29.013  1   87.77  ? 318 TYR D C   1 
ATOM   1197 O  O   . TYR A 1 148 ? -61.451 -13.417 28.622  1   95.81  ? 318 TYR D O   1 
ATOM   1198 C  CB  . TYR A 1 148 ? -58.546 -14.056 27.854  1   78.5   ? 318 TYR D CB  1 
ATOM   1199 C  CG  . TYR A 1 148 ? -57.471 -14.223 26.785  1   74.96  ? 318 TYR D CG  1 
ATOM   1200 C  CD1 . TYR A 1 148 ? -57.266 -13.283 25.776  1   75.16  ? 318 TYR D CD1 1 
ATOM   1201 C  CD2 . TYR A 1 148 ? -56.657 -15.356 26.784  1   71.47  ? 318 TYR D CD2 1 
ATOM   1202 C  CE1 . TYR A 1 148 ? -56.273 -13.466 24.82   1   73.96  ? 318 TYR D CE1 1 
ATOM   1203 C  CE2 . TYR A 1 148 ? -55.67  -15.549 25.829  1   70.14  ? 318 TYR D CE2 1 
ATOM   1204 C  CZ  . TYR A 1 148 ? -55.465 -14.596 24.844  1   71.42  ? 318 TYR D CZ  1 
ATOM   1205 O  OH  . TYR A 1 148 ? -54.466 -14.773 23.916  1   70.06  ? 318 TYR D OH  1 
ATOM   1206 N  N   . PHE A 1 149 ? -60.236 -12.467 30.271  1   84.32  ? 319 PHE D N   1 
ATOM   1207 C  CA  . PHE A 1 149 ? -61.277 -12.621 31.272  1   87.91  ? 319 PHE D CA  1 
ATOM   1208 C  C   . PHE A 1 149 ? -62.443 -11.685 30.984  1   94.17  ? 319 PHE D C   1 
ATOM   1209 O  O   . PHE A 1 149 ? -63.581 -12.019 31.31   1   98.68  ? 319 PHE D O   1 
ATOM   1210 C  CB  . PHE A 1 149 ? -60.779 -12.394 32.695  1   87.35  ? 319 PHE D CB  1 
ATOM   1211 C  CG  . PHE A 1 149 ? -59.883 -13.504 33.217  1   89.53  ? 319 PHE D CG  1 
ATOM   1212 C  CD1 . PHE A 1 149 ? -59.806 -14.733 32.562  1   88.24  ? 319 PHE D CD1 1 
ATOM   1213 C  CD2 . PHE A 1 149 ? -59.11  -13.307 34.359  1   88.34  ? 319 PHE D CD2 1 
ATOM   1214 C  CE1 . PHE A 1 149 ? -58.978 -15.733 33.051  1   87.91  ? 319 PHE D CE1 1 
ATOM   1215 C  CE2 . PHE A 1 149 ? -58.294 -14.318 34.843  1   87.61  ? 319 PHE D CE2 1 
ATOM   1216 C  CZ  . PHE A 1 149 ? -58.222 -15.528 34.186  1   85.42  ? 319 PHE D CZ  1 
ATOM   1217 N  N   . LEU A 1 150 ? -62.155 -10.53  30.372  1   92.8   ? 320 LEU D N   1 
ATOM   1218 C  CA  . LEU A 1 150 ? -63.173 -9.519  30.136  1   97.25  ? 320 LEU D CA  1 
ATOM   1219 C  C   . LEU A 1 150 ? -64.173 -9.984  29.08   1   102.65 ? 320 LEU D C   1 
ATOM   1220 O  O   . LEU A 1 150 ? -65.131 -9.274  28.784  1   106.17 ? 320 LEU D O   1 
ATOM   1221 C  CB  . LEU A 1 150 ? -62.507 -8.202  29.737  1   95.9   ? 320 LEU D CB  1 
ATOM   1222 C  CG  . LEU A 1 150 ? -61.5   -7.622  30.736  1   95.28  ? 320 LEU D CG  1 
ATOM   1223 C  CD1 . LEU A 1 150 ? -61.035 -6.256  30.265  1   93.49  ? 320 LEU D CD1 1 
ATOM   1224 C  CD2 . LEU A 1 150 ? -62.058 -7.529  32.153  1   96.64  ? 320 LEU D CD2 1 
ATOM   1225 N  N   . HIS A 1 151 ? -63.94  -11.164 28.498  1   103.6  ? 321 HIS D N   1 
ATOM   1226 C  CA  . HIS A 1 151 ? -64.829 -11.691 27.477  1   108.68 ? 321 HIS D CA  1 
ATOM   1227 C  C   . HIS A 1 151 ? -65.723 -12.773 28.077  1   110.17 ? 321 HIS D C   1 
ATOM   1228 O  O   . HIS A 1 151 ? -66.46  -13.418 27.347  1   114.99 ? 321 HIS D O   1 
ATOM   1229 C  CB  . HIS A 1 151 ? -64.034 -12.181 26.261  1   112.9  ? 321 HIS D CB  1 
ATOM   1230 C  CG  . HIS A 1 151 ? -63.519 -11.118 25.339  1   116.31 ? 321 HIS D CG  1 
ATOM   1231 N  ND1 . HIS A 1 151 ? -63.883 -11.058 24.009  1   124.84 ? 321 HIS D ND1 1 
ATOM   1232 C  CD2 . HIS A 1 151 ? -62.638 -10.127 25.515  1   114.14 ? 321 HIS D CD2 1 
ATOM   1233 C  CE1 . HIS A 1 151 ? -63.259 -10.046 23.42   1   121.24 ? 321 HIS D CE1 1 
ATOM   1234 N  NE2 . HIS A 1 151 ? -62.501 -9.464  24.319  1   113.61 ? 321 HIS D NE2 1 
ATOM   1235 N  N   . GLN A 1 152 ? -65.655 -12.973 29.4    1   109.53 ? 322 GLN D N   1 
ATOM   1236 C  CA  . GLN A 1 152 ? -66.633 -13.796 30.099  1   114.2  ? 322 GLN D CA  1 
ATOM   1237 C  C   . GLN A 1 152 ? -67.967 -13.052 30.156  1   121.43 ? 322 GLN D C   1 
ATOM   1238 O  O   . GLN A 1 152 ? -68.017 -11.842 29.93   1   119.3  ? 322 GLN D O   1 
ATOM   1239 C  CB  . GLN A 1 152 ? -66.194 -14.075 31.535  1   114.02 ? 322 GLN D CB  1 
ATOM   1240 C  CG  . GLN A 1 152 ? -65.079 -15.105 31.663  1   118.98 ? 322 GLN D CG  1 
ATOM   1241 C  CD  . GLN A 1 152 ? -64.758 -15.47  33.095  1   120.58 ? 322 GLN D CD  1 
ATOM   1242 O  OE1 . GLN A 1 152 ? -65.072 -16.57  33.565  1   125.18 ? 322 GLN D OE1 1 
ATOM   1243 N  NE2 . GLN A 1 152 ? -64.142 -14.537 33.809  1   111.77 ? 322 GLN D NE2 1 
ATOM   1244 N  N   . GLN A 1 153 ? -69.048 -13.787 30.459  1   127.42 ? 323 GLN D N   1 
ATOM   1245 C  CA  . GLN A 1 153 ? -70.283 -13.148 30.885  1   133.18 ? 323 GLN D CA  1 
ATOM   1246 C  C   . GLN A 1 153 ? -71.255 -14.184 31.442  1   139.56 ? 323 GLN D C   1 
ATOM   1247 O  O   . GLN A 1 153 ? -71.819 -14.967 30.681  1   141    ? 323 GLN D O   1 
ATOM   1248 C  CB  . GLN A 1 153 ? -70.948 -12.326 29.786  1   136.17 ? 323 GLN D CB  1 
ATOM   1249 C  CG  . GLN A 1 153 ? -71.721 -11.142 30.348  1   143.5  ? 323 GLN D CG  1 
ATOM   1250 C  CD  . GLN A 1 153 ? -72.706 -10.561 29.362  1   152.21 ? 323 GLN D CD  1 
ATOM   1251 O  OE1 . GLN A 1 153 ? -72.354 -10.194 28.236  1   153.3  ? 323 GLN D OE1 1 
ATOM   1252 N  NE2 . GLN A 1 153 ? -73.964 -10.48  29.771  1   158.95 ? 323 GLN D NE2 1 
ATOM   1253 N  N   . PRO A 1 154 ? -71.507 -14.208 32.775  1   142.6  ? 324 PRO D N   1 
ATOM   1254 C  CA  . PRO A 1 154 ? -70.887 -13.264 33.715  1   136.91 ? 324 PRO D CA  1 
ATOM   1255 C  C   . PRO A 1 154 ? -69.408 -13.575 33.942  1   132.48 ? 324 PRO D C   1 
ATOM   1256 O  O   . PRO A 1 154 ? -68.852 -14.458 33.287  1   131.85 ? 324 PRO D O   1 
ATOM   1257 C  CB  . PRO A 1 154 ? -71.704 -13.472 34.995  1   138.94 ? 324 PRO D CB  1 
ATOM   1258 C  CG  . PRO A 1 154 ? -72.137 -14.923 34.91   1   145.31 ? 324 PRO D CG  1 
ATOM   1259 C  CD  . PRO A 1 154 ? -72.415 -15.164 33.436  1   147.33 ? 324 PRO D CD  1 
ATOM   1260 N  N   . ALA A 1 155 ? -68.779 -12.822 34.853  1   124.19 ? 325 ALA D N   1 
ATOM   1261 C  CA  . ALA A 1 155 ? -67.449 -13.13  35.349  1   113.55 ? 325 ALA D CA  1 
ATOM   1262 C  C   . ALA A 1 155 ? -67.541 -14.328 36.295  1   112.63 ? 325 ALA D C   1 
ATOM   1263 O  O   . ALA A 1 155 ? -68.553 -14.524 36.959  1   116.51 ? 325 ALA D O   1 
ATOM   1264 C  CB  . ALA A 1 155 ? -66.864 -11.906 36.026  1   107.39 ? 325 ALA D CB  1 
ATOM   1265 N  N   . ASN A 1 156 ? -66.479 -15.131 36.348  1   110.66 ? 326 ASN D N   1 
ATOM   1266 C  CA  . ASN A 1 156 ? -66.481 -16.362 37.12   1   112.69 ? 326 ASN D CA  1 
ATOM   1267 C  C   . ASN A 1 156 ? -65.197 -16.421 37.95   1   109.84 ? 326 ASN D C   1 
ATOM   1268 O  O   . ASN A 1 156 ? -64.099 -16.401 37.404  1   100.11 ? 326 ASN D O   1 
ATOM   1269 C  CB  . ASN A 1 156 ? -66.657 -17.561 36.191  1   113.81 ? 326 ASN D CB  1 
ATOM   1270 C  CG  . ASN A 1 156 ? -67.228 -18.789 36.861  1   115.91 ? 326 ASN D CG  1 
ATOM   1271 O  OD1 . ASN A 1 156 ? -66.719 -19.242 37.893  1   113.86 ? 326 ASN D OD1 1 
ATOM   1272 N  ND2 . ASN A 1 156 ? -68.277 -19.351 36.277  1   122.52 ? 326 ASN D ND2 1 
ATOM   1273 N  N   . CYS A 1 157 ? -65.355 -16.497 39.278  1   116.55 ? 327 CYS D N   1 
ATOM   1274 C  CA  . CYS A 1 157 ? -64.242 -16.532 40.215  1   118.13 ? 327 CYS D CA  1 
ATOM   1275 C  C   . CYS A 1 157 ? -63.362 -17.754 39.989  1   114.97 ? 327 CYS D C   1 
ATOM   1276 O  O   . CYS A 1 157 ? -62.144 -17.618 39.983  1   108.71 ? 327 CYS D O   1 
ATOM   1277 C  CB  . CYS A 1 157 ? -64.716 -16.628 41.66   1   129.94 ? 327 CYS D CB  1 
ATOM   1278 S  SG  . CYS A 1 157 ? -64.759 -15.026 42.502  1   146.35 ? 327 CYS D SG  1 
ATOM   1279 N  N   . LYS A 1 158 ? -63.992 -18.932 39.845  1   118.55 ? 328 LYS D N   1 
ATOM   1280 C  CA  . LYS A 1 158 ? -63.293 -20.21  39.799  1   112.6  ? 328 LYS D CA  1 
ATOM   1281 C  C   . LYS A 1 158 ? -62.563 -20.396 38.465  1   109.48 ? 328 LYS D C   1 
ATOM   1282 O  O   . LYS A 1 158 ? -61.454 -20.937 38.45   1   103.2  ? 328 LYS D O   1 
ATOM   1283 C  CB  . LYS A 1 158 ? -64.26  -21.357 40.106  1   110.85 ? 328 LYS D CB  1 
ATOM   1284 C  CG  . LYS A 1 158 ? -64.601 -21.56  41.572  1   111.02 ? 328 LYS D CG  1 
ATOM   1285 C  CD  . LYS A 1 158 ? -65.661 -22.649 41.691  1   114.57 ? 328 LYS D CD  1 
ATOM   1286 C  CE  . LYS A 1 158 ? -65.826 -23.338 43.011  1   113.8  ? 328 LYS D CE  1 
ATOM   1287 N  NZ  . LYS A 1 158 ? -66.872 -24.361 42.887  1   113.76 ? 328 LYS D NZ  1 
ATOM   1288 N  N   . VAL A 1 159 ? -63.186 -19.947 37.362  1   107.76 ? 329 VAL D N   1 
ATOM   1289 C  CA  . VAL A 1 159 ? -62.6   -20.04  36.034  1   102.93 ? 329 VAL D CA  1 
ATOM   1290 C  C   . VAL A 1 159 ? -61.339 -19.175 35.978  1   101.17 ? 329 VAL D C   1 
ATOM   1291 O  O   . VAL A 1 159 ? -60.298 -19.635 35.502  1   102.17 ? 329 VAL D O   1 
ATOM   1292 C  CB  . VAL A 1 159 ? -63.613 -19.696 34.927  1   101.43 ? 329 VAL D CB  1 
ATOM   1293 C  CG1 . VAL A 1 159 ? -62.975 -19.564 33.553  1   98.59  ? 329 VAL D CG1 1 
ATOM   1294 C  CG2 . VAL A 1 159 ? -64.718 -20.733 34.859  1   110.47 ? 329 VAL D CG2 1 
ATOM   1295 N  N   . GLU A 1 160 ? -61.431 -17.942 36.5    1   97.51  ? 330 GLU D N   1 
ATOM   1296 C  CA  . GLU A 1 160 ? -60.298 -17.026 36.545  1   90.29  ? 330 GLU D CA  1 
ATOM   1297 C  C   . GLU A 1 160 ? -59.177 -17.65  37.366  1   85.76  ? 330 GLU D C   1 
ATOM   1298 O  O   . GLU A 1 160 ? -58.06  -17.756 36.878  1   83.84  ? 330 GLU D O   1 
ATOM   1299 C  CB  . GLU A 1 160 ? -60.678 -15.635 37.048  1   89.58  ? 330 GLU D CB  1 
ATOM   1300 C  CG  . GLU A 1 160 ? -61.616 -14.917 36.084  1   94.8   ? 330 GLU D CG  1 
ATOM   1301 C  CD  . GLU A 1 160 ? -61.965 -13.483 36.424  1   94.5   ? 330 GLU D CD  1 
ATOM   1302 O  OE1 . GLU A 1 160 ? -61.284 -12.914 37.285  1   92.71  ? 330 GLU D OE1 1 
ATOM   1303 O  OE2 . GLU A 1 160 ? -62.929 -12.951 35.844  1   98.95  ? 330 GLU D OE2 1 
ATOM   1304 N  N   . SER A 1 161 ? -59.485 -18.081 38.592  1   86.69  ? 331 SER D N   1 
ATOM   1305 C  CA  . SER A 1 161 ? -58.518 -18.793 39.411  1   87.52  ? 331 SER D CA  1 
ATOM   1306 C  C   . SER A 1 161 ? -57.952 -19.982 38.636  1   87.13  ? 331 SER D C   1 
ATOM   1307 O  O   . SER A 1 161 ? -56.74  -20.093 38.465  1   83.93  ? 331 SER D O   1 
ATOM   1308 C  CB  . SER A 1 161 ? -59.112 -19.229 40.731  1   93.73  ? 331 SER D CB  1 
ATOM   1309 O  OG  . SER A 1 161 ? -59.459 -18.116 41.545  1   97.92  ? 331 SER D OG  1 
ATOM   1310 N  N   . LEU A 1 162 ? -58.838 -20.857 38.146  1   90.47  ? 332 LEU D N   1 
ATOM   1311 C  CA  . LEU A 1 162 ? -58.402 -22.104 37.547  1   88.31  ? 332 LEU D CA  1 
ATOM   1312 C  C   . LEU A 1 162 ? -57.46  -21.837 36.37   1   84.65  ? 332 LEU D C   1 
ATOM   1313 O  O   . LEU A 1 162 ? -56.509 -22.585 36.177  1   85.31  ? 332 LEU D O   1 
ATOM   1314 C  CB  . LEU A 1 162 ? -59.587 -22.985 37.161  1   89.13  ? 332 LEU D CB  1 
ATOM   1315 C  CG  . LEU A 1 162 ? -59.232 -24.343 36.543  1   89.94  ? 332 LEU D CG  1 
ATOM   1316 C  CD1 . LEU A 1 162 ? -58.16  -25.06  37.342  1   89.86  ? 332 LEU D CD1 1 
ATOM   1317 C  CD2 . LEU A 1 162 ? -60.444 -25.249 36.433  1   94.4   ? 332 LEU D CD2 1 
ATOM   1318 N  N   . ALA A 1 163 ? -57.713 -20.773 35.615  1   82.22  ? 333 ALA D N   1 
ATOM   1319 C  CA  . ALA A 1 163 ? -56.876 -20.489 34.429  1   82.14  ? 333 ALA D CA  1 
ATOM   1320 C  C   . ALA A 1 163 ? -55.454 -20.157 34.876  1   81.94  ? 333 ALA D C   1 
ATOM   1321 O  O   . ALA A 1 163 ? -54.485 -20.656 34.275  1   78.99  ? 333 ALA D O   1 
ATOM   1322 C  CB  . ALA A 1 163 ? -57.476 -19.36  33.644  1   80.93  ? 333 ALA D CB  1 
ATOM   1323 N  N   . MET A 1 164 ? -55.339 -19.338 35.915  1   83.55  ? 334 MET D N   1 
ATOM   1324 C  CA  . MET A 1 164 ? -54.008 -18.939 36.426  1   86.39  ? 334 MET D CA  1 
ATOM   1325 C  C   . MET A 1 164 ? -53.263 -20.189 36.894  1   82.91  ? 334 MET D C   1 
ATOM   1326 O  O   . MET A 1 164 ? -52.053 -20.28  36.635  1   82.32  ? 334 MET D O   1 
ATOM   1327 C  CB  . MET A 1 164 ? -54.157 -17.965 37.597  1   90.89  ? 334 MET D CB  1 
ATOM   1328 C  CG  . MET A 1 164 ? -55.037 -16.773 37.292  1   92.64  ? 334 MET D CG  1 
ATOM   1329 S  SD  . MET A 1 164 ? -54.153 -15.44  36.461  1   99.44  ? 334 MET D SD  1 
ATOM   1330 C  CE  . MET A 1 164 ? -54.078 -14.245 37.801  1   97.24  ? 334 MET D CE  1 
ATOM   1331 N  N   . PHE A 1 165 ? -53.967 -21.107 37.552  1   81.2   ? 335 PHE D N   1 
ATOM   1332 C  CA  . PHE A 1 165 ? -53.333 -22.349 38.063  1   78.47  ? 335 PHE D CA  1 
ATOM   1333 C  C   . PHE A 1 165 ? -52.625 -23.034 36.923  1   76.74  ? 335 PHE D C   1 
ATOM   1334 O  O   . PHE A 1 165 ? -51.441 -23.38  37.047  1   78.06  ? 335 PHE D O   1 
ATOM   1335 C  CB  . PHE A 1 165 ? -54.439 -23.213 38.664  1   79.5   ? 335 PHE D CB  1 
ATOM   1336 C  CG  . PHE A 1 165 ? -54.034 -24.625 39.053  1   82.95  ? 335 PHE D CG  1 
ATOM   1337 C  CD1 . PHE A 1 165 ? -53.108 -24.848 40.063  1   81.63  ? 335 PHE D CD1 1 
ATOM   1338 C  CD2 . PHE A 1 165 ? -54.592 -25.725 38.415  1   86.84  ? 335 PHE D CD2 1 
ATOM   1339 C  CE1 . PHE A 1 165 ? -52.746 -26.135 40.417  1   85.42  ? 335 PHE D CE1 1 
ATOM   1340 C  CE2 . PHE A 1 165 ? -54.228 -27.01  38.775  1   87.47  ? 335 PHE D CE2 1 
ATOM   1341 C  CZ  . PHE A 1 165 ? -53.308 -27.212 39.775  1   88.14  ? 335 PHE D CZ  1 
ATOM   1342 N  N   . LEU A 1 166 ? -53.336 -23.219 35.818  1   77.15  ? 336 LEU D N   1 
ATOM   1343 C  CA  . LEU A 1 166 ? -52.751 -23.928 34.657  1   76.78  ? 336 LEU D CA  1 
ATOM   1344 C  C   . LEU A 1 166 ? -51.572 -23.113 34.124  1   75.05  ? 336 LEU D C   1 
ATOM   1345 O  O   . LEU A 1 166 ? -50.509 -23.71  33.861  1   73.47  ? 336 LEU D O   1 
ATOM   1346 C  CB  . LEU A 1 166 ? -53.843 -24.118 33.609  1   78.28  ? 336 LEU D CB  1 
ATOM   1347 C  CG  . LEU A 1 166 ? -55.162 -24.698 34.128  1   80.63  ? 336 LEU D CG  1 
ATOM   1348 C  CD1 . LEU A 1 166 ? -56.274 -24.586 33.106  1   82.52  ? 336 LEU D CD1 1 
ATOM   1349 C  CD2 . LEU A 1 166 ? -54.995 -26.134 34.583  1   81.57  ? 336 LEU D CD2 1 
ATOM   1350 N  N   . GLY A 1 167 ? -51.76  -21.802 33.982  1   73.65  ? 337 GLY D N   1 
ATOM   1351 C  CA  . GLY A 1 167 ? -50.677 -20.933 33.496  1   67.76  ? 337 GLY D CA  1 
ATOM   1352 C  C   . GLY A 1 167 ? -49.422 -21.156 34.3    1   67.77  ? 337 GLY D C   1 
ATOM   1353 O  O   . GLY A 1 167 ? -48.356 -21.342 33.694  1   68.95  ? 337 GLY D O   1 
ATOM   1354 N  N   . GLU A 1 168 ? -49.543 -21.166 35.623  1   66.88  ? 338 GLU D N   1 
ATOM   1355 C  CA  . GLU A 1 168 ? -48.339 -21.286 36.48   1   64.12  ? 338 GLU D CA  1 
ATOM   1356 C  C   . GLU A 1 168 ? -47.718 -22.682 36.319  1   65.67  ? 338 GLU D C   1 
ATOM   1357 O  O   . GLU A 1 168 ? -46.481 -22.774 36.321  1   65.92  ? 338 GLU D O   1 
ATOM   1358 C  CB  . GLU A 1 168 ? -48.714 -20.919 37.913  1   61.75  ? 338 GLU D CB  1 
ATOM   1359 C  CG  . GLU A 1 168 ? -48.728 -19.411 38.134  1   62.97  ? 338 GLU D CG  1 
ATOM   1360 C  CD  . GLU A 1 168 ? -49.175 -18.99  39.516  1   65.22  ? 338 GLU D CD  1 
ATOM   1361 O  OE1 . GLU A 1 168 ? -48.735 -19.612 40.5    1   64.73  ? 338 GLU D OE1 1 
ATOM   1362 O  OE2 . GLU A 1 168 ? -49.967 -18.033 39.597  1   66.22  ? 338 GLU D OE2 1 
ATOM   1363 N  N   . LEU A 1 169 ? -48.541 -23.712 36.15   1   63.79  ? 339 LEU D N   1 
ATOM   1364 C  CA  . LEU A 1 169 ? -48.019 -25.092 35.986  1   63.92  ? 339 LEU D CA  1 
ATOM   1365 C  C   . LEU A 1 169 ? -47.198 -25.171 34.693  1   64.12  ? 339 LEU D C   1 
ATOM   1366 O  O   . LEU A 1 169 ? -46.288 -26.009 34.633  1   69.58  ? 339 LEU D O   1 
ATOM   1367 C  CB  . LEU A 1 169 ? -49.166 -26.095 35.992  1   67.39  ? 339 LEU D CB  1 
ATOM   1368 C  CG  . LEU A 1 169 ? -49.818 -26.382 37.346  1   68.57  ? 339 LEU D CG  1 
ATOM   1369 C  CD1 . LEU A 1 169 ? -50.953 -27.359 37.122  1   71.47  ? 339 LEU D CD1 1 
ATOM   1370 C  CD2 . LEU A 1 169 ? -48.798 -26.97  38.297  1   68.51  ? 339 LEU D CD2 1 
ATOM   1371 N  N   . SER A 1 170 ? -47.506 -24.325 33.714  1   60.98  ? 340 SER D N   1 
ATOM   1372 C  CA  . SER A 1 170 ? -46.741 -24.29  32.444  1   60.27  ? 340 SER D CA  1 
ATOM   1373 C  C   . SER A 1 170 ? -45.329 -23.76  32.693  1   62.6   ? 340 SER D C   1 
ATOM   1374 O  O   . SER A 1 170 ? -44.396 -24.215 32.013  1   64.25  ? 340 SER D O   1 
ATOM   1375 C  CB  . SER A 1 170 ? -47.439 -23.438 31.445  1   59.88  ? 340 SER D CB  1 
ATOM   1376 O  OG  . SER A 1 170 ? -47.143 -22.067 31.657  1   60.96  ? 340 SER D OG  1 
ATOM   1377 N  N   . LEU A 1 171 ? -45.181 -22.834 33.637  1   63.71  ? 341 LEU D N   1 
ATOM   1378 C  CA  . LEU A 1 171 ? -43.859 -22.209 33.889  1   61.99  ? 341 LEU D CA  1 
ATOM   1379 C  C   . LEU A 1 171 ? -42.862 -23.259 34.394  1   61.85  ? 341 LEU D C   1 
ATOM   1380 O  O   . LEU A 1 171 ? -41.656 -23.013 34.273  1   62.14  ? 341 LEU D O   1 
ATOM   1381 C  CB  . LEU A 1 171 ? -44.035 -21.078 34.901  1   58.45  ? 341 LEU D CB  1 
ATOM   1382 C  CG  . LEU A 1 171 ? -45.078 -20.008 34.576  1   57.28  ? 341 LEU D CG  1 
ATOM   1383 C  CD1 . LEU A 1 171 ? -45.226 -19.106 35.783  1   58.53  ? 341 LEU D CD1 1 
ATOM   1384 C  CD2 . LEU A 1 171 ? -44.648 -19.2   33.371  1   53.2   ? 341 LEU D CD2 1 
ATOM   1385 N  N   . ILE A 1 172 ? -43.34  -24.395 34.892  1   59.1   ? 342 ILE D N   1 
ATOM   1386 C  CA  . ILE A 1 172 ? -42.436 -25.389 35.541  1   58.11  ? 342 ILE D CA  1 
ATOM   1387 C  C   . ILE A 1 172 ? -41.801 -26.343 34.527  1   59.07  ? 342 ILE D C   1 
ATOM   1388 O  O   . ILE A 1 172 ? -40.687 -26.82  34.798  1   60.08  ? 342 ILE D O   1 
ATOM   1389 C  CB  . ILE A 1 172 ? -43.245 -26.16  36.599  1   56.99  ? 342 ILE D CB  1 
ATOM   1390 C  CG1 . ILE A 1 172 ? -43.917 -25.211 37.579  1   54.45  ? 342 ILE D CG1 1 
ATOM   1391 C  CG2 . ILE A 1 172 ? -42.382 -27.191 37.325  1   57.92  ? 342 ILE D CG2 1 
ATOM   1392 C  CD1 . ILE A 1 172 ? -43.232 -25.146 38.93   1   52.59  ? 342 ILE D CD1 1 
ATOM   1393 N  N   . ASP A 1 173 ? -42.427 -26.551 33.376  1   58.85  ? 343 ASP D N   1 
ATOM   1394 C  CA  . ASP A 1 173 ? -41.956 -27.582 32.478  1   60.36  ? 343 ASP D CA  1 
ATOM   1395 C  C   . ASP A 1 173 ? -41.563 -26.958 31.148  1   60.54  ? 343 ASP D C   1 
ATOM   1396 O  O   . ASP A 1 173 ? -42.425 -26.801 30.287  1   67.13  ? 343 ASP D O   1 
ATOM   1397 C  CB  . ASP A 1 173 ? -43.035 -28.634 32.326  1   63.85  ? 343 ASP D CB  1 
ATOM   1398 C  CG  . ASP A 1 173 ? -43.314 -29.399 33.608  1   69.69  ? 343 ASP D CG  1 
ATOM   1399 O  OD1 . ASP A 1 173 ? -42.36  -30.062 34.078  1   71.24  ? 343 ASP D OD1 1 
ATOM   1400 O  OD2 . ASP A 1 173 ? -44.461 -29.294 34.138  1   71.77  ? 343 ASP D OD2 1 
ATOM   1401 N  N   . ALA A 1 174 ? -40.271 -26.636 30.993  1   56.31  ? 344 ALA D N   1 
ATOM   1402 C  CA  . ALA A 1 174 ? -39.718 -26.133 29.744  1   57.2   ? 344 ALA D CA  1 
ATOM   1403 C  C   . ALA A 1 174 ? -40.136 -27.019 28.578  1   61.28  ? 344 ALA D C   1 
ATOM   1404 O  O   . ALA A 1 174 ? -40.399 -26.52  27.482  1   65.32  ? 344 ALA D O   1 
ATOM   1405 C  CB  . ALA A 1 174 ? -38.218 -26.024 29.805  1   54.44  ? 344 ALA D CB  1 
ATOM   1406 N  N   . ASP A 1 175 ? -40.141 -28.33  28.806  1   61.14  ? 345 ASP D N   1 
ATOM   1407 C  CA  . ASP A 1 175 ? -40.682 -29.213 27.795  1   66.22  ? 345 ASP D CA  1 
ATOM   1408 C  C   . ASP A 1 175 ? -42.062 -29.658 28.277  1   70.56  ? 345 ASP D C   1 
ATOM   1409 O  O   . ASP A 1 175 ? -42.164 -30.27  29.336  1   75.41  ? 345 ASP D O   1 
ATOM   1410 C  CB  . ASP A 1 175 ? -39.724 -30.349 27.47   1   68.2   ? 345 ASP D CB  1 
ATOM   1411 C  CG  . ASP A 1 175 ? -40.315 -31.491 26.657  1   72.16  ? 345 ASP D CG  1 
ATOM   1412 O  OD1 . ASP A 1 175 ? -41.487 -31.406 26.223  1   72.6   ? 345 ASP D OD1 1 
ATOM   1413 O  OD2 . ASP A 1 175 ? -39.59  -32.475 26.467  1   74.49  ? 345 ASP D OD2 1 
ATOM   1414 N  N   . PRO A 1 176 ? -43.168 -29.385 27.542  1   68.03  ? 346 PRO D N   1 
ATOM   1415 C  CA  . PRO A 1 176 ? -43.111 -28.73  26.235  1   67.48  ? 346 PRO D CA  1 
ATOM   1416 C  C   . PRO A 1 176 ? -43.23  -27.212 26.099  1   69.35  ? 346 PRO D C   1 
ATOM   1417 O  O   . PRO A 1 176 ? -43.075 -26.719 24.984  1   72.18  ? 346 PRO D O   1 
ATOM   1418 C  CB  . PRO A 1 176 ? -44.311 -29.416 25.587  1   68.97  ? 346 PRO D CB  1 
ATOM   1419 C  CG  . PRO A 1 176 ? -45.336 -29.526 26.692  1   67.49  ? 346 PRO D CG  1 
ATOM   1420 C  CD  . PRO A 1 176 ? -44.534 -29.738 27.947  1   66.03  ? 346 PRO D CD  1 
ATOM   1421 N  N   . TYR A 1 177 ? -43.47  -26.482 27.205  1   66.61  ? 347 TYR D N   1 
ATOM   1422 C  CA  . TYR A 1 177 ? -44.156 -25.186 27.165  1   66.59  ? 347 TYR D CA  1 
ATOM   1423 C  C   . TYR A 1 177 ? -43.313 -24.025 26.62   1   66.82  ? 347 TYR D C   1 
ATOM   1424 O  O   . TYR A 1 177 ? -43.85  -22.942 26.375  1   66.16  ? 347 TYR D O   1 
ATOM   1425 C  CB  . TYR A 1 177 ? -44.842 -24.859 28.5    1   63.71  ? 347 TYR D CB  1 
ATOM   1426 C  CG  . TYR A 1 177 ? -45.921 -25.868 28.85   1   69.19  ? 347 TYR D CG  1 
ATOM   1427 C  CD1 . TYR A 1 177 ? -47.043 -26.02  28.033  1   71.97  ? 347 TYR D CD1 1 
ATOM   1428 C  CD2 . TYR A 1 177 ? -45.806 -26.711 29.955  1   71.22  ? 347 TYR D CD2 1 
ATOM   1429 C  CE1 . TYR A 1 177 ? -48.016 -26.973 28.307  1   75.88  ? 347 TYR D CE1 1 
ATOM   1430 C  CE2 . TYR A 1 177 ? -46.786 -27.655 30.245  1   74.11  ? 347 TYR D CE2 1 
ATOM   1431 C  CZ  . TYR A 1 177 ? -47.892 -27.793 29.418  1   76.74  ? 347 TYR D CZ  1 
ATOM   1432 O  OH  . TYR A 1 177 ? -48.87  -28.713 29.677  1   77.44  ? 347 TYR D OH  1 
ATOM   1433 N  N   . LEU A 1 178 ? -42.004 -24.232 26.424  1   69.11  ? 348 LEU D N   1 
ATOM   1434 C  CA  . LEU A 1 178 ? -41.145 -23.226 25.802  1   69.85  ? 348 LEU D CA  1 
ATOM   1435 C  C   . LEU A 1 178 ? -41.472 -23.025 24.317  1   73.61  ? 348 LEU D C   1 
ATOM   1436 O  O   . LEU A 1 178 ? -41.126 -22.001 23.724  1   72.92  ? 348 LEU D O   1 
ATOM   1437 C  CB  . LEU A 1 178 ? -39.675 -23.614 25.955  1   68.73  ? 348 LEU D CB  1 
ATOM   1438 C  CG  . LEU A 1 178 ? -38.941 -23.14  27.215  1   67.95  ? 348 LEU D CG  1 
ATOM   1439 C  CD1 . LEU A 1 178 ? -37.459 -23.49  27.061  1   66.79  ? 348 LEU D CD1 1 
ATOM   1440 C  CD2 . LEU A 1 178 ? -39.111 -21.653 27.464  1   60.59  ? 348 LEU D CD2 1 
ATOM   1441 N  N   . LYS A 1 179 ? -42.098 -24.024 23.685  1   74.37  ? 349 LYS D N   1 
ATOM   1442 C  CA  . LYS A 1 179 ? -42.347 -23.901 22.261  1   78.8   ? 349 LYS D CA  1 
ATOM   1443 C  C   . LYS A 1 179 ? -43.722 -23.281 22.006  1   79.58  ? 349 LYS D C   1 
ATOM   1444 O  O   . LYS A 1 179 ? -44.145 -23.192 20.862  1   84.6   ? 349 LYS D O   1 
ATOM   1445 C  CB  . LYS A 1 179 ? -42.013 -25.187 21.498  1   82.56  ? 349 LYS D CB  1 
ATOM   1446 C  CG  . LYS A 1 179 ? -42.931 -26.379 21.733  1   86.55  ? 349 LYS D CG  1 
ATOM   1447 C  CD  . LYS A 1 179 ? -42.27  -27.704 21.355  1   84.95  ? 349 LYS D CD  1 
ATOM   1448 C  CE  . LYS A 1 179 ? -43.171 -28.862 21.649  1   87.6   ? 349 LYS D CE  1 
ATOM   1449 N  NZ  . LYS A 1 179 ? -42.42  -30.112 21.795  1   88.38  ? 349 LYS D NZ  1 
ATOM   1450 N  N   . TYR A 1 180 ? -44.393 -22.817 23.066  1   75.1   ? 350 TYR D N   1 
ATOM   1451 C  CA  . TYR A 1 180 ? -45.638 -22.08  22.918  1   70.47  ? 350 TYR D CA  1 
ATOM   1452 C  C   . TYR A 1 180 ? -45.463 -20.655 23.43   1   66.29  ? 350 TYR D C   1 
ATOM   1453 O  O   . TYR A 1 180 ? -44.805 -20.432 24.445  1   63.09  ? 350 TYR D O   1 
ATOM   1454 C  CB  . TYR A 1 180 ? -46.746 -22.757 23.722  1   72.4   ? 350 TYR D CB  1 
ATOM   1455 C  CG  . TYR A 1 180 ? -47.039 -24.182 23.283  1   75.44  ? 350 TYR D CG  1 
ATOM   1456 C  CD1 . TYR A 1 180 ? -47.697 -24.442 22.084  1   77.15  ? 350 TYR D CD1 1 
ATOM   1457 C  CD2 . TYR A 1 180 ? -46.657 -25.264 24.066  1   74.22  ? 350 TYR D CD2 1 
ATOM   1458 C  CE1 . TYR A 1 180 ? -47.966 -25.74  21.677  1   78.33  ? 350 TYR D CE1 1 
ATOM   1459 C  CE2 . TYR A 1 180 ? -46.939 -26.561 23.674  1   74.54  ? 350 TYR D CE2 1 
ATOM   1460 C  CZ  . TYR A 1 180 ? -47.593 -26.802 22.48   1   76.78  ? 350 TYR D CZ  1 
ATOM   1461 O  OH  . TYR A 1 180 ? -47.85  -28.087 22.1    1   78.69  ? 350 TYR D OH  1 
ATOM   1462 N  N   . LEU A 1 181 ? -46.07  -19.707 22.707  1   64.51  ? 351 LEU D N   1 
ATOM   1463 C  CA  . LEU A 1 181 ? -46.095 -18.303 23.086  1   62.74  ? 351 LEU D CA  1 
ATOM   1464 C  C   . LEU A 1 181 ? -47.066 -18.078 24.249  1   65.59  ? 351 LEU D C   1 
ATOM   1465 O  O   . LEU A 1 181 ? -48.043 -18.807 24.419  1   69.78  ? 351 LEU D O   1 
ATOM   1466 C  CB  . LEU A 1 181 ? -46.471 -17.44  21.886  1   61.84  ? 351 LEU D CB  1 
ATOM   1467 C  CG  . LEU A 1 181 ? -45.43  -17.298 20.768  1   61.01  ? 351 LEU D CG  1 
ATOM   1468 C  CD1 . LEU A 1 181 ? -46.018 -16.562 19.564  1   61.12  ? 351 LEU D CD1 1 
ATOM   1469 C  CD2 . LEU A 1 181 ? -44.194 -16.584 21.282  1   55.93  ? 351 LEU D CD2 1 
ATOM   1470 N  N   . PRO A 1 182 ? -46.804 -17.07  25.111  1   62.19  ? 352 PRO D N   1 
ATOM   1471 C  CA  . PRO A 1 182 ? -47.689 -16.762 26.239  1   62.43  ? 352 PRO D CA  1 
ATOM   1472 C  C   . PRO A 1 182 ? -49.16  -16.6   25.884  1   67.48  ? 352 PRO D C   1 
ATOM   1473 O  O   . PRO A 1 182 ? -50.02  -17.188 26.528  1   75.01  ? 352 PRO D O   1 
ATOM   1474 C  CB  . PRO A 1 182 ? -47.098 -15.446 26.738  1   59.33  ? 352 PRO D CB  1 
ATOM   1475 C  CG  . PRO A 1 182 ? -45.626 -15.547 26.406  1   56.02  ? 352 PRO D CG  1 
ATOM   1476 C  CD  . PRO A 1 182 ? -45.608 -16.21  25.058  1   58.24  ? 352 PRO D CD  1 
ATOM   1477 N  N   . SER A 1 183 ? -49.432 -15.797 24.854  1   68.51  ? 353 SER D N   1 
ATOM   1478 C  CA  . SER A 1 183 ? -50.785 -15.579 24.368  1   70     ? 353 SER D CA  1 
ATOM   1479 C  C   . SER A 1 183 ? -51.489 -16.905 24.09   1   73.35  ? 353 SER D C   1 
ATOM   1480 O  O   . SER A 1 183 ? -52.697 -16.996 24.281  1   76.77  ? 353 SER D O   1 
ATOM   1481 C  CB  . SER A 1 183 ? -50.77  -14.742 23.128  1   70.07  ? 353 SER D CB  1 
ATOM   1482 O  OG  . SER A 1 183 ? -50.112 -15.451 22.091  1   69.34  ? 353 SER D OG  1 
ATOM   1483 N  N   . VAL A 1 184 ? -50.736 -17.9   23.594  1   72.64  ? 354 VAL D N   1 
ATOM   1484 C  CA  . VAL A 1 184 ? -51.285 -19.198 23.228  1   72.69  ? 354 VAL D CA  1 
ATOM   1485 C  C   . VAL A 1 184 ? -51.551 -19.999 24.5    1   73.04  ? 354 VAL D C   1 
ATOM   1486 O  O   . VAL A 1 184 ? -52.638 -20.556 24.683  1   73.47  ? 354 VAL D O   1 
ATOM   1487 C  CB  . VAL A 1 184 ? -50.393 -19.982 22.244  1   69.99  ? 354 VAL D CB  1 
ATOM   1488 C  CG1 . VAL A 1 184 ? -50.753 -21.459 22.18   1   68.06  ? 354 VAL D CG1 1 
ATOM   1489 C  CG2 . VAL A 1 184 ? -50.411 -19.361 20.853  1   70.97  ? 354 VAL D CG2 1 
ATOM   1490 N  N   . ILE A 1 185 ? -50.546 -20.049 25.384  1   68.58  ? 355 ILE D N   1 
ATOM   1491 C  CA  . ILE A 1 185 ? -50.727 -20.825 26.593  1   67.53  ? 355 ILE D CA  1 
ATOM   1492 C  C   . ILE A 1 185 ? -51.935 -20.255 27.328  1   69.23  ? 355 ILE D C   1 
ATOM   1493 O  O   . ILE A 1 185 ? -52.809 -21.012 27.734  1   72.28  ? 355 ILE D O   1 
ATOM   1494 C  CB  . ILE A 1 185 ? -49.455 -20.873 27.455  1   63.83  ? 355 ILE D CB  1 
ATOM   1495 C  CG1 . ILE A 1 185 ? -48.273 -21.453 26.678  1   61.05  ? 355 ILE D CG1 1 
ATOM   1496 C  CG2 . ILE A 1 185 ? -49.73  -21.679 28.726  1   64.36  ? 355 ILE D CG2 1 
ATOM   1497 C  CD1 . ILE A 1 185 ? -46.959 -21.42  27.438  1   55.35  ? 355 ILE D CD1 1 
ATOM   1498 N  N   . ALA A 1 186 ? -51.991 -18.919 27.431  1   66.54  ? 356 ALA D N   1 
ATOM   1499 C  CA  . ALA A 1 186 ? -53.083 -18.204 28.076  1   66.36  ? 356 ALA D CA  1 
ATOM   1500 C  C   . ALA A 1 186 ? -54.439 -18.653 27.536  1   71.81  ? 356 ALA D C   1 
ATOM   1501 O  O   . ALA A 1 186 ? -55.364 -18.904 28.302  1   73.15  ? 356 ALA D O   1 
ATOM   1502 C  CB  . ALA A 1 186 ? -52.902 -16.728 27.871  1   62.96  ? 356 ALA D CB  1 
ATOM   1503 N  N   . ALA A 1 187 ? -54.548 -18.731 26.204  1   72.9   ? 357 ALA D N   1 
ATOM   1504 C  CA  . ALA A 1 187 ? -55.772 -19.146 25.545  1   76.59  ? 357 ALA D CA  1 
ATOM   1505 C  C   . ALA A 1 187 ? -56.1   -20.602 25.884  1   80.61  ? 357 ALA D C   1 
ATOM   1506 O  O   . ALA A 1 187 ? -57.25  -20.926 26.164  1   84.67  ? 357 ALA D O   1 
ATOM   1507 C  CB  . ALA A 1 187 ? -55.627 -18.927 24.062  1   77.17  ? 357 ALA D CB  1 
ATOM   1508 N  N   . ALA A 1 188 ? -55.087 -21.479 25.872  1   80.05  ? 358 ALA D N   1 
ATOM   1509 C  CA  . ALA A 1 188 ? -55.297 -22.888 26.161  1   82.11  ? 358 ALA D CA  1 
ATOM   1510 C  C   . ALA A 1 188 ? -55.726 -23.082 27.613  1   82.86  ? 358 ALA D C   1 
ATOM   1511 O  O   . ALA A 1 188 ? -56.548 -23.952 27.914  1   85.46  ? 358 ALA D O   1 
ATOM   1512 C  CB  . ALA A 1 188 ? -54.049 -23.669 25.853  1   80.18  ? 358 ALA D CB  1 
ATOM   1513 N  N   . ALA A 1 189 ? -55.159 -22.26  28.501  1   80.37  ? 359 ALA D N   1 
ATOM   1514 C  CA  . ALA A 1 189 ? -55.507 -22.293 29.912  1   81.05  ? 359 ALA D CA  1 
ATOM   1515 C  C   . ALA A 1 189 ? -56.927 -21.762 30.124  1   85.14  ? 359 ALA D C   1 
ATOM   1516 O  O   . ALA A 1 189 ? -57.642 -22.259 30.993  1   89.2   ? 359 ALA D O   1 
ATOM   1517 C  CB  . ALA A 1 189 ? -54.479 -21.528 30.705  1   74.96  ? 359 ALA D CB  1 
ATOM   1518 N  N   . PHE A 1 190 ? -57.332 -20.782 29.321  1   83.58  ? 360 PHE D N   1 
ATOM   1519 C  CA  . PHE A 1 190 ? -58.667 -20.165 29.53   1   85.13  ? 360 PHE D CA  1 
ATOM   1520 C  C   . PHE A 1 190 ? -59.726 -21.176 29.143  1   91.22  ? 360 PHE D C   1 
ATOM   1521 O  O   . PHE A 1 190 ? -60.596 -21.493 29.973  1   93.35  ? 360 PHE D O   1 
ATOM   1522 C  CB  . PHE A 1 190 ? -58.832 -18.871 28.731  1   83.71  ? 360 PHE D CB  1 
ATOM   1523 C  CG  . PHE A 1 190 ? -60.083 -18.079 29.079  1   87.11  ? 360 PHE D CG  1 
ATOM   1524 C  CD1 . PHE A 1 190 ? -60.526 -17.988 30.393  1   88.07  ? 360 PHE D CD1 1 
ATOM   1525 C  CD2 . PHE A 1 190 ? -60.815 -17.433 28.091  1   90.96  ? 360 PHE D CD2 1 
ATOM   1526 C  CE1 . PHE A 1 190 ? -61.668 -17.27  30.705  1   92.54  ? 360 PHE D CE1 1 
ATOM   1527 C  CE2 . PHE A 1 190 ? -61.955 -16.717 28.411  1   92.23  ? 360 PHE D CE2 1 
ATOM   1528 C  CZ  . PHE A 1 190 ? -62.376 -16.635 29.715  1   93.3   ? 360 PHE D CZ  1 
ATOM   1529 N  N   . HIS A 1 191 ? -59.653 -21.678 27.914  1   92.24  ? 361 HIS D N   1 
ATOM   1530 C  CA  . HIS A 1 191 ? -60.604 -22.728 27.476  1   96.8   ? 361 HIS D CA  1 
ATOM   1531 C  C   . HIS A 1 191 ? -60.695 -23.825 28.534  1   99.77  ? 361 HIS D C   1 
ATOM   1532 O  O   . HIS A 1 191 ? -61.765 -24.013 29.131  1   108.9  ? 361 HIS D O   1 
ATOM   1533 C  CB  . HIS A 1 191 ? -60.133 -23.363 26.17   1   95.39  ? 361 HIS D CB  1 
ATOM   1534 C  CG  . HIS A 1 191 ? -60.952 -24.543 25.772  1   99.23  ? 361 HIS D CG  1 
ATOM   1535 N  ND1 . HIS A 1 191 ? -62.172 -24.418 25.147  1   101.55 ? 361 HIS D ND1 1 
ATOM   1536 C  CD2 . HIS A 1 191 ? -60.744 -25.854 25.919  1   99.19  ? 361 HIS D CD2 1 
ATOM   1537 C  CE1 . HIS A 1 191 ? -62.672 -25.622 24.924  1   104.81 ? 361 HIS D CE1 1 
ATOM   1538 N  NE2 . HIS A 1 191 ? -61.821 -26.508 25.387  1   103.61 ? 361 HIS D NE2 1 
ATOM   1539 N  N   . LEU A 1 192 ? -59.599 -24.543 28.747  1   97.97  ? 362 LEU D N   1 
ATOM   1540 C  CA  . LEU A 1 192 ? -59.641 -25.69  29.682  1   101.41 ? 362 LEU D CA  1 
ATOM   1541 C  C   . LEU A 1 192 ? -60.428 -25.31  30.936  1   100.8  ? 362 LEU D C   1 
ATOM   1542 O  O   . LEU A 1 192 ? -61.298 -26.097 31.346  1   104.65 ? 362 LEU D O   1 
ATOM   1543 C  CB  . LEU A 1 192 ? -58.211 -26.101 30.015  1   104.1  ? 362 LEU D CB  1 
ATOM   1544 C  CG  . LEU A 1 192 ? -58.035 -27.462 30.695  1   110.92 ? 362 LEU D CG  1 
ATOM   1545 C  CD1 . LEU A 1 192 ? -58.908 -28.512 30.036  1   116.46 ? 362 LEU D CD1 1 
ATOM   1546 C  CD2 . LEU A 1 192 ? -56.577 -27.882 30.662  1   116.21 ? 362 LEU D CD2 1 
ATOM   1547 N  N   . ALA A 1 193 ? -60.147 -24.145 31.509  1   99.7   ? 363 ALA D N   1 
ATOM   1548 C  CA  . ALA A 1 193 ? -60.794 -23.78  32.789  1   103.46 ? 363 ALA D CA  1 
ATOM   1549 C  C   . ALA A 1 193 ? -62.285 -23.56  32.566  1   109.58 ? 363 ALA D C   1 
ATOM   1550 O  O   . ALA A 1 193 ? -63.094 -24.145 33.309  1   116.52 ? 363 ALA D O   1 
ATOM   1551 C  CB  . ALA A 1 193 ? -60.153 -22.546 33.364  1   96.26  ? 363 ALA D CB  1 
ATOM   1552 N  N   . LEU A 1 194 ? -62.625 -22.729 31.586  1   107.66 ? 364 LEU D N   1 
ATOM   1553 C  CA  . LEU A 1 194 ? -64.052 -22.485 31.276  1   110.02 ? 364 LEU D CA  1 
ATOM   1554 C  C   . LEU A 1 194 ? -64.759 -23.848 31.219  1   116.5  ? 364 LEU D C   1 
ATOM   1555 O  O   . LEU A 1 194 ? -65.672 -24.083 32.036  1   124.01 ? 364 LEU D O   1 
ATOM   1556 C  CB  . LEU A 1 194 ? -64.137 -21.725 29.956  1   107.04 ? 364 LEU D CB  1 
ATOM   1557 C  CG  . LEU A 1 194 ? -63.549 -20.314 29.942  1   110.06 ? 364 LEU D CG  1 
ATOM   1558 C  CD1 . LEU A 1 194 ? -63.567 -19.735 28.543  1   110.35 ? 364 LEU D CD1 1 
ATOM   1559 C  CD2 . LEU A 1 194 ? -64.335 -19.436 30.894  1   109.97 ? 364 LEU D CD2 1 
ATOM   1560 N  N   . TYR A 1 195 ? -64.328 -24.72  30.312  1   113.95 ? 365 TYR D N   1 
ATOM   1561 C  CA  . TYR A 1 195 ? -64.971 -26.047 30.152  1   115.01 ? 365 TYR D CA  1 
ATOM   1562 C  C   . TYR A 1 195 ? -65.121 -26.71  31.498  1   115.9  ? 365 TYR D C   1 
ATOM   1563 O  O   . TYR A 1 195 ? -66.249 -27.037 31.905  1   118.51 ? 365 TYR D O   1 
ATOM   1564 C  CB  . TYR A 1 195 ? -64.055 -26.863 29.242  1   111.97 ? 365 TYR D CB  1 
ATOM   1565 C  CG  . TYR A 1 195 ? -64.572 -28.23  28.824  1   115.85 ? 365 TYR D CG  1 
ATOM   1566 C  CD1 . TYR A 1 195 ? -64.349 -29.354 29.609  1   121.02 ? 365 TYR D CD1 1 
ATOM   1567 C  CD2 . TYR A 1 195 ? -65.264 -28.398 27.632  1   117.41 ? 365 TYR D CD2 1 
ATOM   1568 C  CE1 . TYR A 1 195 ? -64.812 -30.601 29.228  1   126.4  ? 365 TYR D CE1 1 
ATOM   1569 C  CE2 . TYR A 1 195 ? -65.729 -29.641 27.239  1   122.47 ? 365 TYR D CE2 1 
ATOM   1570 C  CZ  . TYR A 1 195 ? -65.502 -30.746 28.039  1   127.39 ? 365 TYR D CZ  1 
ATOM   1571 O  OH  . TYR A 1 195 ? -65.959 -31.974 27.659  1   131.98 ? 365 TYR D OH  1 
ATOM   1572 N  N   . THR A 1 196 ? -64.013 -26.896 32.201  1   110.92 ? 366 THR D N   1 
ATOM   1573 C  CA  . THR A 1 196 ? -64.058 -27.652 33.466  1   111.43 ? 366 THR D CA  1 
ATOM   1574 C  C   . THR A 1 196 ? -65.127 -27.148 34.417  1   113.57 ? 366 THR D C   1 
ATOM   1575 O  O   . THR A 1 196 ? -65.816 -28.002 35.007  1   115.26 ? 366 THR D O   1 
ATOM   1576 C  CB  . THR A 1 196 ? -62.671 -27.595 34.103  1   107.28 ? 366 THR D CB  1 
ATOM   1577 O  OG1 . THR A 1 196 ? -61.78  -27.97  33.059  1   106.25 ? 366 THR D OG1 1 
ATOM   1578 C  CG2 . THR A 1 196 ? -62.528 -28.529 35.292  1   105.54 ? 366 THR D CG2 1 
ATOM   1579 N  N   . VAL A 1 197 ? -65.293 -25.835 34.577  1   111.28 ? 367 VAL D N   1 
ATOM   1580 C  CA  . VAL A 1 197 ? -66.219 -25.33  35.639  1   115.56 ? 367 VAL D CA  1 
ATOM   1581 C  C   . VAL A 1 197 ? -67.605 -24.982 35.085  1   122.01 ? 367 VAL D C   1 
ATOM   1582 O  O   . VAL A 1 197 ? -68.523 -24.768 35.9    1   126.26 ? 367 VAL D O   1 
ATOM   1583 C  CB  . VAL A 1 197 ? -65.58  -24.098 36.306  1   113.2  ? 367 VAL D CB  1 
ATOM   1584 C  CG1 . VAL A 1 197 ? -66.144 -23.837 37.697  1   116.63 ? 367 VAL D CG1 1 
ATOM   1585 C  CG2 . VAL A 1 197 ? -64.064 -24.213 36.376  1   109.71 ? 367 VAL D CG2 1 
ATOM   1586 N  N   . THR A 1 198 ? -67.775 -24.964 33.769  1   123.59 ? 368 THR D N   1 
ATOM   1587 C  CA  . THR A 1 198 ? -69.03  -24.499 33.191  1   126.12 ? 368 THR D CA  1 
ATOM   1588 C  C   . THR A 1 198 ? -69.52  -25.413 32.07   1   126.84 ? 368 THR D C   1 
ATOM   1589 O  O   . THR A 1 198 ? -70.721 -25.605 31.927  1   130.86 ? 368 THR D O   1 
ATOM   1590 C  CB  . THR A 1 198 ? -68.883 -23.045 32.737  1   123.62 ? 368 THR D CB  1 
ATOM   1591 O  OG1 . THR A 1 198 ? -67.815 -22.962 31.795  1   118.06 ? 368 THR D OG1 1 
ATOM   1592 C  CG2 . THR A 1 198 ? -68.617 -22.103 33.899  1   122.54 ? 368 THR D CG2 1 
ATOM   1593 N  N   . GLY A 1 199 ? -68.597 -25.949 31.264  1   124.15 ? 369 GLY D N   1 
ATOM   1594 C  CA  . GLY A 1 199 ? -68.968 -26.758 30.112  1   126.22 ? 369 GLY D CA  1 
ATOM   1595 C  C   . GLY A 1 199 ? -68.865 -25.975 28.804  1   123.35 ? 369 GLY D C   1 
ATOM   1596 O  O   . GLY A 1 199 ? -69.323 -26.437 27.768  1   123.53 ? 369 GLY D O   1 
ATOM   1597 N  N   . GLN A 1 200 ? -68.216 -24.806 28.851  1   120.78 ? 370 GLN D N   1 
ATOM   1598 C  CA  . GLN A 1 200 ? -68.254 -23.846 27.759  1   121.54 ? 370 GLN D CA  1 
ATOM   1599 C  C   . GLN A 1 200 ? -66.874 -23.711 27.124  1   115.19 ? 370 GLN D C   1 
ATOM   1600 O  O   . GLN A 1 200 ? -65.862 -23.948 27.775  1   112.65 ? 370 GLN D O   1 
ATOM   1601 C  CB  . GLN A 1 200 ? -68.711 -22.495 28.304  1   124.46 ? 370 GLN D CB  1 
ATOM   1602 C  CG  . GLN A 1 200 ? -70.072 -22.541 28.989  1   131.16 ? 370 GLN D CG  1 
ATOM   1603 C  CD  . GLN A 1 200 ? -70.342 -21.325 29.847  1   131.67 ? 370 GLN D CD  1 
ATOM   1604 O  OE1 . GLN A 1 200 ? -69.602 -20.33  29.82   1   122.79 ? 370 GLN D OE1 1 
ATOM   1605 N  NE2 . GLN A 1 200 ? -71.423 -21.398 30.613  1   136.9  ? 370 GLN D NE2 1 
ATOM   1606 N  N   . SER A 1 201 ? -66.856 -23.311 25.848  1   113.91 ? 371 SER D N   1 
ATOM   1607 C  CA  . SER A 1 201 ? -65.637 -23.275 25.058  1   110.96 ? 371 SER D CA  1 
ATOM   1608 C  C   . SER A 1 201 ? -65.077 -21.859 24.946  1   109.99 ? 371 SER D C   1 
ATOM   1609 O  O   . SER A 1 201 ? -65.755 -20.879 25.252  1   108.73 ? 371 SER D O   1 
ATOM   1610 C  CB  . SER A 1 201 ? -65.846 -23.878 23.695  1   112.1  ? 371 SER D CB  1 
ATOM   1611 O  OG  . SER A 1 201 ? -65.831 -25.294 23.766  1   113.07 ? 371 SER D OG  1 
ATOM   1612 N  N   . TRP A 1 202 ? -63.798 -21.799 24.553  1   107.8  ? 372 TRP D N   1 
ATOM   1613 C  CA  . TRP A 1 202 ? -63.168 -20.652 23.92   1   108.53 ? 372 TRP D CA  1 
ATOM   1614 C  C   . TRP A 1 202 ? -64.211 -19.866 23.126  1   114.25 ? 372 TRP D C   1 
ATOM   1615 O  O   . TRP A 1 202 ? -64.639 -20.318 22.065  1   118.9  ? 372 TRP D O   1 
ATOM   1616 C  CB  . TRP A 1 202 ? -62.039 -21.17  23.011  1   106.19 ? 372 TRP D CB  1 
ATOM   1617 C  CG  . TRP A 1 202 ? -61.198 -20.114 22.346  1   104.16 ? 372 TRP D CG  1 
ATOM   1618 C  CD1 . TRP A 1 202 ? -61.122 -19.858 21.007  1   104.94 ? 372 TRP D CD1 1 
ATOM   1619 C  CD2 . TRP A 1 202 ? -60.313 -19.166 22.991  1   99.56  ? 372 TRP D CD2 1 
ATOM   1620 N  NE1 . TRP A 1 202 ? -60.253 -18.824 20.773  1   103.49 ? 372 TRP D NE1 1 
ATOM   1621 C  CE2 . TRP A 1 202 ? -59.746 -18.376 21.966  1   97.21  ? 372 TRP D CE2 1 
ATOM   1622 C  CE3 . TRP A 1 202 ? -59.952 -18.901 24.321  1   98.19  ? 372 TRP D CE3 1 
ATOM   1623 C  CZ2 . TRP A 1 202 ? -58.844 -17.351 22.236  1   91.3   ? 372 TRP D CZ2 1 
ATOM   1624 C  CZ3 . TRP A 1 202 ? -59.057 -17.884 24.588  1   90.86  ? 372 TRP D CZ3 1 
ATOM   1625 C  CH2 . TRP A 1 202 ? -58.522 -17.118 23.555  1   89.26  ? 372 TRP D CH2 1 
ATOM   1626 N  N   . PRO A 1 203 ? -64.645 -18.672 23.603  1   117.52 ? 373 PRO D N   1 
ATOM   1627 C  CA  . PRO A 1 203 ? -65.735 -17.928 22.967  1   123.8  ? 373 PRO D CA  1 
ATOM   1628 C  C   . PRO A 1 203 ? -65.351 -17.251 21.653  1   124.77 ? 373 PRO D C   1 
ATOM   1629 O  O   . PRO A 1 203 ? -64.171 -17.017 21.387  1   116.9  ? 373 PRO D O   1 
ATOM   1630 C  CB  . PRO A 1 203 ? -66.219 -16.907 24.027  1   124.83 ? 373 PRO D CB  1 
ATOM   1631 C  CG  . PRO A 1 203 ? -65.192 -16.954 25.146  1   119.24 ? 373 PRO D CG  1 
ATOM   1632 C  CD  . PRO A 1 203 ? -64.11  -17.965 24.776  1   116.67 ? 373 PRO D CD  1 
ATOM   1633 N  N   . GLU A 1 204 ? -66.386 -16.915 20.871  1   128.52 ? 374 GLU D N   1 
ATOM   1634 C  CA  . GLU A 1 204 ? -66.247 -16.397 19.522  1   130.31 ? 374 GLU D CA  1 
ATOM   1635 C  C   . GLU A 1 204 ? -65.524 -15.05  19.526  1   125.37 ? 374 GLU D C   1 
ATOM   1636 O  O   . GLU A 1 204 ? -64.613 -14.829 18.731  1   124.04 ? 374 GLU D O   1 
ATOM   1637 C  CB  . GLU A 1 204 ? -67.635 -16.31  18.885  1   132.13 ? 374 GLU D CB  1 
ATOM   1638 C  CG  . GLU A 1 204 ? -67.598 -15.75  17.464  1   129.38 ? 374 GLU D CG  1 
ATOM   1639 C  CD  . GLU A 1 204 ? -66.749 -16.541 16.471  1   130.51 ? 374 GLU D CD  1 
ATOM   1640 O  OE1 . GLU A 1 204 ? -66.393 -17.716 16.764  1   126.69 ? 374 GLU D OE1 1 
ATOM   1641 O  OE2 . GLU A 1 204 ? -66.439 -15.964 15.402  1   132.26 ? 374 GLU D OE2 1 
ATOM   1642 N  N   . SER A 1 205 ? -65.957 -14.147 20.415  1   123.3  ? 375 SER D N   1 
ATOM   1643 C  CA  . SER A 1 205 ? -65.431 -12.792 20.504  1   119.09 ? 375 SER D CA  1 
ATOM   1644 C  C   . SER A 1 205 ? -63.907 -12.791 20.67   1   113.07 ? 375 SER D C   1 
ATOM   1645 O  O   . SER A 1 205 ? -63.227 -11.87  20.215  1   107.13 ? 375 SER D O   1 
ATOM   1646 C  CB  . SER A 1 205 ? -66.116 -12.029 21.616  1   119.08 ? 375 SER D CB  1 
ATOM   1647 O  OG  . SER A 1 205 ? -65.907 -12.659 22.874  1   115.37 ? 375 SER D OG  1 
ATOM   1648 N  N   . LEU A 1 206 ? -63.381 -13.831 21.327  1   110.14 ? 376 LEU D N   1 
ATOM   1649 C  CA  . LEU A 1 206 ? -61.944 -14.002 21.494  1   103.67 ? 376 LEU D CA  1 
ATOM   1650 C  C   . LEU A 1 206 ? -61.304 -14.556 20.224  1   103    ? 376 LEU D C   1 
ATOM   1651 O  O   . LEU A 1 206 ? -60.126 -14.307 19.986  1   102.93 ? 376 LEU D O   1 
ATOM   1652 C  CB  . LEU A 1 206 ? -61.626 -14.88  22.702  1   99.17  ? 376 LEU D CB  1 
ATOM   1653 C  CG  . LEU A 1 206 ? -61.829 -14.228 24.072  1   96.19  ? 376 LEU D CG  1 
ATOM   1654 C  CD1 . LEU A 1 206 ? -61.448 -15.177 25.183  1   92.92  ? 376 LEU D CD1 1 
ATOM   1655 C  CD2 . LEU A 1 206 ? -61.041 -12.938 24.168  1   93.92  ? 376 LEU D CD2 1 
ATOM   1656 N  N   . VAL A 1 207 ? -62.069 -15.308 19.421  1   99.63  ? 377 VAL D N   1 
ATOM   1657 C  CA  . VAL A 1 207 ? -61.548 -15.797 18.158  1   99.11  ? 377 VAL D CA  1 
ATOM   1658 C  C   . VAL A 1 207 ? -61.3   -14.621 17.212  1   100.65 ? 377 VAL D C   1 
ATOM   1659 O  O   . VAL A 1 207 ? -60.322 -14.63  16.469  1   98.94  ? 377 VAL D O   1 
ATOM   1660 C  CB  . VAL A 1 207 ? -62.451 -16.875 17.524  1   102.61 ? 377 VAL D CB  1 
ATOM   1661 C  CG1 . VAL A 1 207 ? -62.004 -17.281 16.122  1   100.34 ? 377 VAL D CG1 1 
ATOM   1662 C  CG2 . VAL A 1 207 ? -62.558 -18.104 18.413  1   101.32 ? 377 VAL D CG2 1 
ATOM   1663 N  N   . GLN A 1 208 ? -62.189 -13.62  17.234  1   105.06 ? 378 GLN D N   1 
ATOM   1664 C  CA  . GLN A 1 208 ? -62.035 -12.445 16.384  1   108.84 ? 378 GLN D CA  1 
ATOM   1665 C  C   . GLN A 1 208 ? -60.823 -11.62  16.827  1   103.36 ? 378 GLN D C   1 
ATOM   1666 O  O   . GLN A 1 208 ? -60.111 -11.073 15.985  1   101.14 ? 378 GLN D O   1 
ATOM   1667 C  CB  . GLN A 1 208 ? -63.273 -11.545 16.379  1   115.65 ? 378 GLN D CB  1 
ATOM   1668 C  CG  . GLN A 1 208 ? -64.507 -12.177 15.751  1   127.85 ? 378 GLN D CG  1 
ATOM   1669 C  CD  . GLN A 1 208 ? -64.201 -12.869 14.441  1   133.86 ? 378 GLN D CD  1 
ATOM   1670 O  OE1 . GLN A 1 208 ? -64.517 -14.049 14.26   1   138.77 ? 378 GLN D OE1 1 
ATOM   1671 N  NE2 . GLN A 1 208 ? -63.566 -12.149 13.524  1   133.54 ? 378 GLN D NE2 1 
ATOM   1672 N  N   . LYS A 1 209 ? -60.608 -11.537 18.149  1   97.23  ? 379 LYS D N   1 
ATOM   1673 C  CA  . LYS A 1 209 ? -59.563 -10.707 18.722  1   94.38  ? 379 LYS D CA  1 
ATOM   1674 C  C   . LYS A 1 209 ? -58.182 -11.275 18.399  1   92.26  ? 379 LYS D C   1 
ATOM   1675 O  O   . LYS A 1 209 ? -57.291 -10.515 18.023  1   90.8   ? 379 LYS D O   1 
ATOM   1676 C  CB  . LYS A 1 209 ? -59.737 -10.572 20.241  1   94.83  ? 379 LYS D CB  1 
ATOM   1677 C  CG  . LYS A 1 209 ? -58.824 -9.532  20.901  1   93.52  ? 379 LYS D CG  1 
ATOM   1678 C  CD  . LYS A 1 209 ? -58.769 -9.599  22.424  1   89.86  ? 379 LYS D CD  1 
ATOM   1679 C  CE  . LYS A 1 209 ? -57.991 -8.497  23.071  1   84.76  ? 379 LYS D CE  1 
ATOM   1680 N  NZ  . LYS A 1 209 ? -58.506 -7.179  22.695  1   84.37  ? 379 LYS D NZ  1 
ATOM   1681 N  N   . THR A 1 210 ? -58.014 -12.601 18.565  1   92.43  ? 380 THR D N   1 
ATOM   1682 C  CA  . THR A 1 210 ? -56.708 -13.259 18.596  1   88.08  ? 380 THR D CA  1 
ATOM   1683 C  C   . THR A 1 210 ? -56.364 -13.935 17.265  1   90.12  ? 380 THR D C   1 
ATOM   1684 O  O   . THR A 1 210 ? -55.203 -14.22  16.991  1   92.09  ? 380 THR D O   1 
ATOM   1685 C  CB  . THR A 1 210 ? -56.645 -14.292 19.725  1   87.61  ? 380 THR D CB  1 
ATOM   1686 O  OG1 . THR A 1 210 ? -57.62  -15.305 19.488  1   93.11  ? 380 THR D OG1 1 
ATOM   1687 C  CG2 . THR A 1 210 ? -56.877 -13.694 21.097  1   86.05  ? 380 THR D CG2 1 
ATOM   1688 N  N   . GLY A 1 211 ? -57.366 -14.282 16.461  1   92.39  ? 381 GLY D N   1 
ATOM   1689 C  CA  . GLY A 1 211 ? -57.083 -15.089 15.29   1   93.44  ? 381 GLY D CA  1 
ATOM   1690 C  C   . GLY A 1 211 ? -56.792 -16.545 15.652  1   94.88  ? 381 GLY D C   1 
ATOM   1691 O  O   . GLY A 1 211 ? -56.374 -17.309 14.781  1   95.16  ? 381 GLY D O   1 
ATOM   1692 N  N   . TYR A 1 212 ? -57.087 -16.906 16.904  1   95.46  ? 382 TYR D N   1 
ATOM   1693 C  CA  . TYR A 1 212 ? -56.796 -18.274 17.404  1   99.25  ? 382 TYR D CA  1 
ATOM   1694 C  C   . TYR A 1 212 ? -58.064 -19.103 17.499  1   104.26 ? 382 TYR D C   1 
ATOM   1695 O  O   . TYR A 1 212 ? -58.981 -18.728 18.258  1   105.91 ? 382 TYR D O   1 
ATOM   1696 C  CB  . TYR A 1 212 ? -56.213 -18.244 18.821  1   92.32  ? 382 TYR D CB  1 
ATOM   1697 C  CG  . TYR A 1 212 ? -54.823 -17.652 19.003  1   88.28  ? 382 TYR D CG  1 
ATOM   1698 C  CD1 . TYR A 1 212 ? -53.963 -17.483 17.927  1   87.18  ? 382 TYR D CD1 1 
ATOM   1699 C  CD2 . TYR A 1 212 ? -54.372 -17.273 20.261  1   86.13  ? 382 TYR D CD2 1 
ATOM   1700 C  CE1 . TYR A 1 212 ? -52.698 -16.948 18.098  1   84.89  ? 382 TYR D CE1 1 
ATOM   1701 C  CE2 . TYR A 1 212 ? -53.11  -16.736 20.444  1   82.12  ? 382 TYR D CE2 1 
ATOM   1702 C  CZ  . TYR A 1 212 ? -52.27  -16.575 19.359  1   80.86  ? 382 TYR D CZ  1 
ATOM   1703 O  OH  . TYR A 1 212 ? -51.022 -16.054 19.523  1   74.56  ? 382 TYR D OH  1 
ATOM   1704 N  N   . THR A 1 213 ? -58.117 -20.215 16.765  1   105.62 ? 383 THR D N   1 
ATOM   1705 C  CA  . THR A 1 213 ? -59.244 -21.128 16.876  1   109.62 ? 383 THR D CA  1 
ATOM   1706 C  C   . THR A 1 213 ? -58.868 -22.263 17.827  1   109.09 ? 383 THR D C   1 
ATOM   1707 O  O   . THR A 1 213 ? -57.701 -22.417 18.18   1   105.61 ? 383 THR D O   1 
ATOM   1708 C  CB  . THR A 1 213 ? -59.663 -21.645 15.499  1   114.17 ? 383 THR D CB  1 
ATOM   1709 O  OG1 . THR A 1 213 ? -58.847 -22.774 15.207  1   116.72 ? 383 THR D OG1 1 
ATOM   1710 C  CG2 . THR A 1 213 ? -59.548 -20.589 14.413  1   115.55 ? 383 THR D CG2 1 
ATOM   1711 N  N   . LEU A 1 214 ? -59.877 -23.043 18.237  1   112.49 ? 384 LEU D N   1 
ATOM   1712 C  CA  . LEU A 1 214 ? -59.676 -24.273 18.99   1   109.69 ? 384 LEU D CA  1 
ATOM   1713 C  C   . LEU A 1 214 ? -58.784 -25.224 18.199  1   109.27 ? 384 LEU D C   1 
ATOM   1714 O  O   . LEU A 1 214 ? -57.989 -25.957 18.778  1   109    ? 384 LEU D O   1 
ATOM   1715 C  CB  . LEU A 1 214 ? -61.015 -24.917 19.348  1   109.27 ? 384 LEU D CB  1 
ATOM   1716 C  CG  . LEU A 1 214 ? -61.69  -24.374 20.611  1   108.34 ? 384 LEU D CG  1 
ATOM   1717 C  CD1 . LEU A 1 214 ? -63.132 -24.799 20.737  1   111.23 ? 384 LEU D CD1 1 
ATOM   1718 C  CD2 . LEU A 1 214 ? -60.912 -24.818 21.836  1   106.52 ? 384 LEU D CD2 1 
ATOM   1719 N  N   . GLU A 1 215 ? -58.908 -25.191 16.871  1   111.4  ? 385 GLU D N   1 
ATOM   1720 C  CA  . GLU A 1 215 ? -58.088 -26.043 16.03   1   113.12 ? 385 GLU D CA  1 
ATOM   1721 C  C   . GLU A 1 215 ? -56.616 -25.656 16.19   1   110.09 ? 385 GLU D C   1 
ATOM   1722 O  O   . GLU A 1 215 ? -55.766 -26.532 16.342  1   113.6  ? 385 GLU D O   1 
ATOM   1723 C  CB  . GLU A 1 215 ? -58.586 -26.031 14.585  1   114.99 ? 385 GLU D CB  1 
ATOM   1724 C  CG  . GLU A 1 215 ? -58.276 -27.329 13.847  1   118.85 ? 385 GLU D CG  1 
ATOM   1725 C  CD  . GLU A 1 215 ? -58.408 -27.216 12.339  1   126.47 ? 385 GLU D CD  1 
ATOM   1726 O  OE1 . GLU A 1 215 ? -59.261 -27.903 11.713  1   132.51 ? 385 GLU D OE1 1 
ATOM   1727 O  OE2 . GLU A 1 215 ? -57.627 -26.41  11.789  1   124.79 ? 385 GLU D OE2 1 
ATOM   1728 N  N   . THR A 1 216 ? -56.316 -24.347 16.167  1   104.68 ? 386 THR D N   1 
ATOM   1729 C  CA  . THR A 1 216 ? -54.938 -23.875 16.185  1   101.06 ? 386 THR D CA  1 
ATOM   1730 C  C   . THR A 1 216 ? -54.361 -24.012 17.592  1   97.07  ? 386 THR D C   1 
ATOM   1731 O  O   . THR A 1 216 ? -53.155 -23.895 17.789  1   92.35  ? 386 THR D O   1 
ATOM   1732 C  CB  . THR A 1 216 ? -54.819 -22.423 15.71   1   101.99 ? 386 THR D CB  1 
ATOM   1733 O  OG1 . THR A 1 216 ? -55.286 -21.569 16.756  1   102.1  ? 386 THR D OG1 1 
ATOM   1734 C  CG2 . THR A 1 216 ? -55.543 -22.153 14.404  1   102.68 ? 386 THR D CG2 1 
ATOM   1735 N  N   . LEU A 1 217 ? -55.255 -24.164 18.568  1   96.02  ? 387 LEU D N   1 
ATOM   1736 C  CA  . LEU A 1 217 ? -54.823 -24.219 19.984  1   93.43  ? 387 LEU D CA  1 
ATOM   1737 C  C   . LEU A 1 217 ? -54.828 -25.668 20.472  1   96.9   ? 387 LEU D C   1 
ATOM   1738 O  O   . LEU A 1 217 ? -54.615 -25.887 21.678  1   98.3   ? 387 LEU D O   1 
ATOM   1739 C  CB  . LEU A 1 217 ? -55.793 -23.37  20.8    1   91.27  ? 387 LEU D CB  1 
ATOM   1740 C  CG  . LEU A 1 217 ? -55.721 -21.856 20.595  1   89.72  ? 387 LEU D CG  1 
ATOM   1741 C  CD1 . LEU A 1 217 ? -56.868 -21.201 21.34   1   90.52  ? 387 LEU D CD1 1 
ATOM   1742 C  CD2 . LEU A 1 217 ? -54.392 -21.298 21.059  1   87.88  ? 387 LEU D CD2 1 
ATOM   1743 N  N   . LYS A 1 218 ? -55.06  -26.616 19.57   1   98.91  ? 388 LYS D N   1 
ATOM   1744 C  CA  . LYS A 1 218 ? -55.165 -28.04  19.979  1   99.47  ? 388 LYS D CA  1 
ATOM   1745 C  C   . LYS A 1 218 ? -53.82  -28.523 20.545  1   96.14  ? 388 LYS D C   1 
ATOM   1746 O  O   . LYS A 1 218 ? -53.825 -29.004 21.688  1   96.93  ? 388 LYS D O   1 
ATOM   1747 C  CB  . LYS A 1 218 ? -55.703 -28.864 18.803  1   102.62 ? 388 LYS D CB  1 
ATOM   1748 C  CG  . LYS A 1 218 ? -55.946 -30.341 19.058  1   104.05 ? 388 LYS D CG  1 
ATOM   1749 C  CD  . LYS A 1 218 ? -56.524 -31.041 17.835  1   108.16 ? 388 LYS D CD  1 
ATOM   1750 C  CE  . LYS A 1 218 ? -56.748 -32.5   18.058  1   109.91 ? 388 LYS D CE  1 
ATOM   1751 N  NZ  . LYS A 1 218 ? -57.303 -33.152 16.87   1   115.13 ? 388 LYS D NZ  1 
ATOM   1752 N  N   . PRO A 1 219 ? -52.675 -28.428 19.839  1   93.08  ? 389 PRO D N   1 
ATOM   1753 C  CA  . PRO A 1 219 ? -51.436 -28.941 20.396  1   92.86  ? 389 PRO D CA  1 
ATOM   1754 C  C   . PRO A 1 219 ? -51.23  -28.551 21.852  1   91.77  ? 389 PRO D C   1 
ATOM   1755 O  O   . PRO A 1 219 ? -51.053 -29.438 22.705  1   91.17  ? 389 PRO D O   1 
ATOM   1756 C  CB  . PRO A 1 219 ? -50.412 -28.29  19.474  1   89.7   ? 389 PRO D CB  1 
ATOM   1757 C  CG  . PRO A 1 219 ? -51.103 -28.252 18.14   1   91.51  ? 389 PRO D CG  1 
ATOM   1758 C  CD  . PRO A 1 219 ? -52.511 -27.849 18.51   1   92.11  ? 389 PRO D CD  1 
ATOM   1759 N  N   . CYS A 1 220 ? -51.239 -27.247 22.135  1   91.45  ? 390 CYS D N   1 
ATOM   1760 C  CA  . CYS A 1 220 ? -51.029 -26.75  23.518  1   88.54  ? 390 CYS D CA  1 
ATOM   1761 C  C   . CYS A 1 220 ? -52.098 -27.344 24.435  1   88.32  ? 390 CYS D C   1 
ATOM   1762 O  O   . CYS A 1 220 ? -51.74  -27.853 25.507  1   86.06  ? 390 CYS D O   1 
ATOM   1763 C  CB  . CYS A 1 220 ? -51.108 -25.228 23.569  1   89.16  ? 390 CYS D CB  1 
ATOM   1764 S  SG  . CYS A 1 220 ? -50.61  -24.505 25.152  1   80.2   ? 390 CYS D SG  1 
ATOM   1765 N  N   . LEU A 1 221 ? -53.358 -27.273 24.018  1   92.08  ? 391 LEU D N   1 
ATOM   1766 C  CA  . LEU A 1 221 ? -54.451 -27.762 24.892  1   94.73  ? 391 LEU D CA  1 
ATOM   1767 C  C   . LEU A 1 221 ? -54.164 -29.221 25.262  1   94.61  ? 391 LEU D C   1 
ATOM   1768 O  O   . LEU A 1 221 ? -54.375 -29.583 26.428  1   95.23  ? 391 LEU D O   1 
ATOM   1769 C  CB  . LEU A 1 221 ? -55.808 -27.587 24.216  1   101.55 ? 391 LEU D CB  1 
ATOM   1770 C  CG  . LEU A 1 221 ? -57     -28.128 25.008  1   105.79 ? 391 LEU D CG  1 
ATOM   1771 C  CD1 . LEU A 1 221 ? -57.176 -27.399 26.324  1   106.67 ? 391 LEU D CD1 1 
ATOM   1772 C  CD2 . LEU A 1 221 ? -58.263 -28.067 24.171  1   107.21 ? 391 LEU D CD2 1 
ATOM   1773 N  N   . LEU A 1 222 ? -53.662 -30.002 24.31   1   92.95  ? 392 LEU D N   1 
ATOM   1774 C  CA  . LEU A 1 222 ? -53.309 -31.411 24.605  1   94.32  ? 392 LEU D CA  1 
ATOM   1775 C  C   . LEU A 1 222 ? -52.227 -31.452 25.685  1   93.86  ? 392 LEU D C   1 
ATOM   1776 O  O   . LEU A 1 222 ? -52.495 -31.996 26.773  1   95.76  ? 392 LEU D O   1 
ATOM   1777 C  CB  . LEU A 1 222 ? -52.833 -32.073 23.317  1   93.42  ? 392 LEU D CB  1 
ATOM   1778 C  CG  . LEU A 1 222 ? -53.861 -32.155 22.186  1   97.51  ? 392 LEU D CG  1 
ATOM   1779 C  CD1 . LEU A 1 222 ? -53.214 -32.634 20.9    1   98.06  ? 392 LEU D CD1 1 
ATOM   1780 C  CD2 . LEU A 1 222 ? -55.027 -33.046 22.567  1   96.54  ? 392 LEU D CD2 1 
ATOM   1781 N  N   . ASP A 1 223 ? -51.051 -30.899 25.389  1   89.7   ? 393 ASP D N   1 
ATOM   1782 C  CA  . ASP A 1 223 ? -49.948 -30.956 26.331  1   84.92  ? 393 ASP D CA  1 
ATOM   1783 C  C   . ASP A 1 223 ? -50.425 -30.551 27.719  1   87.87  ? 393 ASP D C   1 
ATOM   1784 O  O   . ASP A 1 223 ? -49.97  -31.13  28.705  1   93.19  ? 393 ASP D O   1 
ATOM   1785 C  CB  . ASP A 1 223 ? -48.801 -30.036 25.958  1   79.93  ? 393 ASP D CB  1 
ATOM   1786 C  CG  . ASP A 1 223 ? -47.888 -30.53  24.852  1   81.16  ? 393 ASP D CG  1 
ATOM   1787 O  OD1 . ASP A 1 223 ? -47.534 -31.737 24.854  1   84.8   ? 393 ASP D OD1 1 
ATOM   1788 O  OD2 . ASP A 1 223 ? -47.529 -29.692 24.014  1   77.74  ? 393 ASP D OD2 1 
ATOM   1789 N  N   . LEU A 1 224 ? -51.33  -29.557 27.771  1   85.64  ? 394 LEU D N   1 
ATOM   1790 C  CA  . LEU A 1 224 ? -51.692 -28.874 29.005  1   81.41  ? 394 LEU D CA  1 
ATOM   1791 C  C   . LEU A 1 224 ? -52.762 -29.657 29.75   1   86.07  ? 394 LEU D C   1 
ATOM   1792 O  O   . LEU A 1 224 ? -52.833 -29.621 30.976  1   83.24  ? 394 LEU D O   1 
ATOM   1793 C  CB  . LEU A 1 224 ? -52.216 -27.489 28.664  1   78.75  ? 394 LEU D CB  1 
ATOM   1794 C  CG  . LEU A 1 224 ? -52.488 -26.573 29.86   1   77.86  ? 394 LEU D CG  1 
ATOM   1795 C  CD1 . LEU A 1 224 ? -51.268 -26.419 30.77   1   73.01  ? 394 LEU D CD1 1 
ATOM   1796 C  CD2 . LEU A 1 224 ? -52.971 -25.217 29.359  1   75.77  ? 394 LEU D CD2 1 
ATOM   1797 N  N   . HIS A 1 225 ? -53.61  -30.331 28.971  1   92.23  ? 395 HIS D N   1 
ATOM   1798 C  CA  . HIS A 1 225 ? -54.61  -31.237 29.494  1   93.74  ? 395 HIS D CA  1 
ATOM   1799 C  C   . HIS A 1 225 ? -53.899 -32.359 30.243  1   94.69  ? 395 HIS D C   1 
ATOM   1800 O  O   . HIS A 1 225 ? -54.354 -32.767 31.308  1   97.23  ? 395 HIS D O   1 
ATOM   1801 C  CB  . HIS A 1 225 ? -55.504 -31.713 28.346  1   97.42  ? 395 HIS D CB  1 
ATOM   1802 C  CG  . HIS A 1 225 ? -56.498 -32.728 28.767  1   101.41 ? 395 HIS D CG  1 
ATOM   1803 N  ND1 . HIS A 1 225 ? -57.403 -32.5   29.781  1   103.03 ? 395 HIS D ND1 1 
ATOM   1804 C  CD2 . HIS A 1 225 ? -56.73  -33.963 28.321  1   104.16 ? 395 HIS D CD2 1 
ATOM   1805 C  CE1 . HIS A 1 225 ? -58.158 -33.575 29.935  1   105.75 ? 395 HIS D CE1 1 
ATOM   1806 N  NE2 . HIS A 1 225 ? -57.769 -34.473 29.056  1   106.52 ? 395 HIS D NE2 1 
ATOM   1807 N  N   . GLN A 1 226 ? -52.776 -32.825 29.678  1   95.81  ? 396 GLN D N   1 
ATOM   1808 C  CA  . GLN A 1 226 ? -51.908 -33.825 30.29   1   99.03  ? 396 GLN D CA  1 
ATOM   1809 C  C   . GLN A 1 226 ? -51.368 -33.31  31.621  1   96.94  ? 396 GLN D C   1 
ATOM   1810 O  O   . GLN A 1 226 ? -51.503 -33.989 32.64   1   100.08 ? 396 GLN D O   1 
ATOM   1811 C  CB  . GLN A 1 226 ? -50.72  -34.188 29.397  1   99.74  ? 396 GLN D CB  1 
ATOM   1812 C  CG  . GLN A 1 226 ? -51.107 -34.922 28.122  1   108.75 ? 396 GLN D CG  1 
ATOM   1813 C  CD  . GLN A 1 226 ? -51.775 -36.246 28.432  1   124.34 ? 396 GLN D CD  1 
ATOM   1814 O  OE1 . GLN A 1 226 ? -52.974 -36.459 28.198  1   123.45 ? 396 GLN D OE1 1 
ATOM   1815 N  NE2 . GLN A 1 226 ? -50.998 -37.145 29.018  1   131.65 ? 396 GLN D NE2 1 
ATOM   1816 N  N   . THR A 1 227 ? -50.773 -32.107 31.592  1   88.89  ? 397 THR D N   1 
ATOM   1817 C  CA  . THR A 1 227 ? -50.106 -31.542 32.756  1   87.58  ? 397 THR D CA  1 
ATOM   1818 C  C   . THR A 1 227 ? -51.083 -31.509 33.931  1   88.7   ? 397 THR D C   1 
ATOM   1819 O  O   . THR A 1 227 ? -50.702 -31.81  35.069  1   88.42  ? 397 THR D O   1 
ATOM   1820 C  CB  . THR A 1 227 ? -49.535 -30.155 32.446  1   82.52  ? 397 THR D CB  1 
ATOM   1821 O  OG1 . THR A 1 227 ? -48.62  -30.265 31.361  1   80.79  ? 397 THR D OG1 1 
ATOM   1822 C  CG2 . THR A 1 227 ? -48.791 -29.554 33.622  1   79.68  ? 397 THR D CG2 1 
ATOM   1823 N  N   . TYR A 1 228 ? -52.341 -31.152 33.63   1   87.04  ? 398 TYR D N   1 
ATOM   1824 C  CA  . TYR A 1 228 ? -53.377 -30.991 34.637  1   88.3   ? 398 TYR D CA  1 
ATOM   1825 C  C   . TYR A 1 228 ? -53.717 -32.363 35.197  1   94.27  ? 398 TYR D C   1 
ATOM   1826 O  O   . TYR A 1 228 ? -53.927 -32.503 36.404  1   98.76  ? 398 TYR D O   1 
ATOM   1827 C  CB  . TYR A 1 228 ? -54.569 -30.287 33.983  1   89.53  ? 398 TYR D CB  1 
ATOM   1828 C  CG  . TYR A 1 228 ? -55.719 -29.848 34.88   1   91.08  ? 398 TYR D CG  1 
ATOM   1829 C  CD1 . TYR A 1 228 ? -55.621 -29.867 36.274  1   89.58  ? 398 TYR D CD1 1 
ATOM   1830 C  CD2 . TYR A 1 228 ? -56.911 -29.393 34.317  1   91.16  ? 398 TYR D CD2 1 
ATOM   1831 C  CE1 . TYR A 1 228 ? -56.683 -29.46  37.07   1   90.16  ? 398 TYR D CE1 1 
ATOM   1832 C  CE2 . TYR A 1 228 ? -57.974 -28.975 35.106  1   90.97  ? 398 TYR D CE2 1 
ATOM   1833 C  CZ  . TYR A 1 228 ? -57.86  -29.011 36.487  1   90.74  ? 398 TYR D CZ  1 
ATOM   1834 O  OH  . TYR A 1 228 ? -58.906 -28.599 37.265  1   91.29  ? 398 TYR D OH  1 
ATOM   1835 N  N   . LEU A 1 229 ? -53.755 -33.357 34.299  1   96.18  ? 399 LEU D N   1 
ATOM   1836 C  CA  . LEU A 1 229 ? -54.094 -34.73  34.635  1   99.32  ? 399 LEU D CA  1 
ATOM   1837 C  C   . LEU A 1 229 ? -53.003 -35.356 35.502  1   101.17 ? 399 LEU D C   1 
ATOM   1838 O  O   . LEU A 1 229 ? -53.312 -36.123 36.411  1   102.82 ? 399 LEU D O   1 
ATOM   1839 C  CB  . LEU A 1 229 ? -54.318 -35.521 33.349  1   99.79  ? 399 LEU D CB  1 
ATOM   1840 C  CG  . LEU A 1 229 ? -55.71  -35.434 32.714  1   100.29 ? 399 LEU D CG  1 
ATOM   1841 C  CD1 . LEU A 1 229 ? -55.755 -36.259 31.433  1   100.75 ? 399 LEU D CD1 1 
ATOM   1842 C  CD2 . LEU A 1 229 ? -56.791 -35.896 33.664  1   102.09 ? 399 LEU D CD2 1 
ATOM   1843 N  N   . ARG A 1 230 ? -51.736 -35.023 35.221  1   100.06 ? 400 ARG D N   1 
ATOM   1844 C  CA  . ARG A 1 230 ? -50.601 -35.6   35.926  1   106.88 ? 400 ARG D CA  1 
ATOM   1845 C  C   . ARG A 1 230 ? -50.185 -34.745 37.123  1   105.53 ? 400 ARG D C   1 
ATOM   1846 O  O   . ARG A 1 230 ? -49.244 -35.109 37.829  1   106.97 ? 400 ARG D O   1 
ATOM   1847 C  CB  . ARG A 1 230 ? -49.384 -35.746 35.004  1   113.26 ? 400 ARG D CB  1 
ATOM   1848 C  CG  . ARG A 1 230 ? -49.488 -36.918 34.04   1   125.48 ? 400 ARG D CG  1 
ATOM   1849 C  CD  . ARG A 1 230 ? -48.305 -37.075 33.092  1   130.26 ? 400 ARG D CD  1 
ATOM   1850 N  NE  . ARG A 1 230 ? -48.642 -38.201 32.212  1   142.58 ? 400 ARG D NE  1 
ATOM   1851 C  CZ  . ARG A 1 230 ? -48.761 -38.189 30.885  1   139.41 ? 400 ARG D CZ  1 
ATOM   1852 N  NH1 . ARG A 1 230 ? -48.393 -37.124 30.188  1   133.7  ? 400 ARG D NH1 1 
ATOM   1853 N  NH2 . ARG A 1 230 ? -49.22  -39.268 30.268  1   134.21 ? 400 ARG D NH2 1 
ATOM   1854 N  N   . ALA A 1 231 ? -50.884 -33.622 37.341  1   101.56 ? 401 ALA D N   1 
ATOM   1855 C  CA  . ALA A 1 231 ? -50.447 -32.607 38.288  1   94.49  ? 401 ALA D CA  1 
ATOM   1856 C  C   . ALA A 1 231 ? -50.145 -33.194 39.67   1   93.02  ? 401 ALA D C   1 
ATOM   1857 O  O   . ALA A 1 231 ? -49.064 -32.948 40.193  1   93.02  ? 401 ALA D O   1 
ATOM   1858 C  CB  . ALA A 1 231 ? -51.443 -31.472 38.348  1   95.18  ? 401 ALA D CB  1 
ATOM   1859 N  N   . PRO A 1 232 ? -51.063 -33.963 40.311  1   94.99  ? 402 PRO D N   1 
ATOM   1860 C  CA  . PRO A 1 232 ? -50.774 -34.609 41.599  1   94.75  ? 402 PRO D CA  1 
ATOM   1861 C  C   . PRO A 1 232 ? -49.589 -35.572 41.681  1   94.84  ? 402 PRO D C   1 
ATOM   1862 O  O   . PRO A 1 232 ? -49.179 -35.933 42.784  1   93.43  ? 402 PRO D O   1 
ATOM   1863 C  CB  . PRO A 1 232 ? -52.074 -35.356 41.93   1   97.65  ? 402 PRO D CB  1 
ATOM   1864 C  CG  . PRO A 1 232 ? -53.137 -34.643 41.135  1   97.78  ? 402 PRO D CG  1 
ATOM   1865 C  CD  . PRO A 1 232 ? -52.447 -34.205 39.859  1   96.02  ? 402 PRO D CD  1 
ATOM   1866 N  N   . GLN A 1 233 ? -49.078 -36.013 40.515  1   94.94  ? 403 GLN D N   1 
ATOM   1867 C  CA  . GLN A 1 233 ? -47.924 -36.907 40.403  1   92.41  ? 403 GLN D CA  1 
ATOM   1868 C  C   . GLN A 1 233 ? -46.642 -36.158 40.038  1   86.47  ? 403 GLN D C   1 
ATOM   1869 O  O   . GLN A 1 233 ? -45.573 -36.763 40.057  1   86.1   ? 403 GLN D O   1 
ATOM   1870 C  CB  . GLN A 1 233 ? -48.105 -38.018 39.365  1   94.16  ? 403 GLN D CB  1 
ATOM   1871 C  CG  . GLN A 1 233 ? -48.685 -39.319 39.909  1   97.07  ? 403 GLN D CG  1 
ATOM   1872 C  CD  . GLN A 1 233 ? -50.052 -39.176 40.543  1   99.43  ? 403 GLN D CD  1 
ATOM   1873 O  OE1 . GLN A 1 233 ? -50.304 -39.709 41.626  1   105.01 ? 403 GLN D OE1 1 
ATOM   1874 N  NE2 . GLN A 1 233 ? -50.966 -38.491 39.87   1   98.2   ? 403 GLN D NE2 1 
ATOM   1875 N  N   . HIS A 1 234 ? -46.745 -34.852 39.754  1   81.48  ? 404 HIS D N   1 
ATOM   1876 C  CA  . HIS A 1 234 ? -45.595 -34.046 39.382  1   78.25  ? 404 HIS D CA  1 
ATOM   1877 C  C   . HIS A 1 234 ? -44.646 -33.902 40.579  1   76.69  ? 404 HIS D C   1 
ATOM   1878 O  O   . HIS A 1 234 ? -45.084 -33.706 41.709  1   76.26  ? 404 HIS D O   1 
ATOM   1879 C  CB  . HIS A 1 234 ? -46.09  -32.718 38.801  1   77.3   ? 404 HIS D CB  1 
ATOM   1880 C  CG  . HIS A 1 234 ? -45.071 -32.045 37.951  1   76.67  ? 404 HIS D CG  1 
ATOM   1881 N  ND1 . HIS A 1 234 ? -43.867 -31.597 38.46   1   74.49  ? 404 HIS D ND1 1 
ATOM   1882 C  CD2 . HIS A 1 234 ? -45.047 -31.774 36.633  1   75.76  ? 404 HIS D CD2 1 
ATOM   1883 C  CE1 . HIS A 1 234 ? -43.155 -31.049 37.488  1   71.67  ? 404 HIS D CE1 1 
ATOM   1884 N  NE2 . HIS A 1 234 ? -43.855 -31.145 36.369  1   74.02  ? 404 HIS D NE2 1 
ATOM   1885 N  N   . ALA A 1 235 ? -43.334 -33.997 40.332  1   74.93  ? 405 ALA D N   1 
ATOM   1886 C  CA  . ALA A 1 235 ? -42.327 -33.905 41.383  1   74.51  ? 405 ALA D CA  1 
ATOM   1887 C  C   . ALA A 1 235 ? -42.391 -32.559 42.104  1   75     ? 405 ALA D C   1 
ATOM   1888 O  O   . ALA A 1 235 ? -41.838 -32.44  43.197  1   74.84  ? 405 ALA D O   1 
ATOM   1889 C  CB  . ALA A 1 235 ? -40.944 -34.137 40.807  1   70.84  ? 405 ALA D CB  1 
ATOM   1890 N  N   . GLN A 1 236 ? -43.032 -31.561 41.466  1   74.82  ? 406 GLN D N   1 
ATOM   1891 C  CA  . GLN A 1 236 ? -43.192 -30.211 41.99   1   74.35  ? 406 GLN D CA  1 
ATOM   1892 C  C   . GLN A 1 236 ? -44.651 -29.946 42.329  1   76.79  ? 406 GLN D C   1 
ATOM   1893 O  O   . GLN A 1 236 ? -45.531 -30.114 41.482  1   79.94  ? 406 GLN D O   1 
ATOM   1894 C  CB  . GLN A 1 236 ? -42.779 -29.16  40.963  1   72.85  ? 406 GLN D CB  1 
ATOM   1895 C  CG  . GLN A 1 236 ? -41.33  -28.708 41.083  1   70.99  ? 406 GLN D CG  1 
ATOM   1896 C  CD  . GLN A 1 236 ? -40.354 -29.858 41.031  1   73.13  ? 406 GLN D CD  1 
ATOM   1897 O  OE1 . GLN A 1 236 ? -40.392 -30.662 40.093  1   77.54  ? 406 GLN D OE1 1 
ATOM   1898 N  NE2 . GLN A 1 236 ? -39.486 -29.942 42.033  1   70.32  ? 406 GLN D NE2 1 
ATOM   1899 N  N   . GLN A 1 237 ? -44.875 -29.471 43.56   1   78.08  ? 407 GLN D N   1 
ATOM   1900 C  CA  . GLN A 1 237 ? -46.21  -29.426 44.138  1   80.25  ? 407 GLN D CA  1 
ATOM   1901 C  C   . GLN A 1 237 ? -46.625 -28.013 44.554  1   80.71  ? 407 GLN D C   1 
ATOM   1902 O  O   . GLN A 1 237 ? -47.801 -27.801 44.84   1   86.37  ? 407 GLN D O   1 
ATOM   1903 C  CB  . GLN A 1 237 ? -46.256 -30.37  45.34   1   80.33  ? 407 GLN D CB  1 
ATOM   1904 C  CG  . GLN A 1 237 ? -46.281 -31.845 44.963  1   82.32  ? 407 GLN D CG  1 
ATOM   1905 C  CD  . GLN A 1 237 ? -47.46  -32.177 44.079  1   81.76  ? 407 GLN D CD  1 
ATOM   1906 O  OE1 . GLN A 1 237 ? -48.568 -31.678 44.288  1   84.55  ? 407 GLN D OE1 1 
ATOM   1907 N  NE2 . GLN A 1 237 ? -47.228 -32.968 43.045  1   78.99  ? 407 GLN D NE2 1 
ATOM   1908 N  N   . SER A 1 238 ? -45.682 -27.056 44.566  1   76.73  ? 408 SER D N   1 
ATOM   1909 C  CA  . SER A 1 238 ? -45.875 -25.776 45.238  1   75.36  ? 408 SER D CA  1 
ATOM   1910 C  C   . SER A 1 238 ? -47.085 -25.013 44.703  1   75.6   ? 408 SER D C   1 
ATOM   1911 O  O   . SER A 1 238 ? -47.737 -24.294 45.457  1   77.51  ? 408 SER D O   1 
ATOM   1912 C  CB  . SER A 1 238 ? -44.651 -24.916 45.167  1   71.67  ? 408 SER D CB  1 
ATOM   1913 O  OG  . SER A 1 238 ? -43.59  -25.497 45.898  1   72.11  ? 408 SER D OG  1 
ATOM   1914 N  N   . ILE A 1 239 ? -47.355 -25.155 43.403  1   73.4   ? 409 ILE D N   1 
ATOM   1915 C  CA  . ILE A 1 239 ? -48.478 -24.481 42.78   1   71.34  ? 409 ILE D CA  1 
ATOM   1916 C  C   . ILE A 1 239 ? -49.785 -25.087 43.293  1   77.65  ? 409 ILE D C   1 
ATOM   1917 O  O   . ILE A 1 239 ? -50.608 -24.376 43.872  1   83.59  ? 409 ILE D O   1 
ATOM   1918 C  CB  . ILE A 1 239 ? -48.33  -24.529 41.252  1   67.92  ? 409 ILE D CB  1 
ATOM   1919 C  CG1 . ILE A 1 239 ? -47.08  -23.749 40.824  1   63.61  ? 409 ILE D CG1 1 
ATOM   1920 C  CG2 . ILE A 1 239 ? -49.588 -24     40.57   1   67.18  ? 409 ILE D CG2 1 
ATOM   1921 C  CD1 . ILE A 1 239 ? -46.742 -23.833 39.35   1   60.58  ? 409 ILE D CD1 1 
ATOM   1922 N  N   . ARG A 1 240 ? -49.953 -26.404 43.13   1   76.46  ? 410 ARG D N   1 
ATOM   1923 C  CA  . ARG A 1 240 ? -51.102 -27.091 43.7    1   80.22  ? 410 ARG D CA  1 
ATOM   1924 C  C   . ARG A 1 240 ? -51.313 -26.675 45.157  1   82.62  ? 410 ARG D C   1 
ATOM   1925 O  O   . ARG A 1 240 ? -52.42  -26.268 45.518  1   83.42  ? 410 ARG D O   1 
ATOM   1926 C  CB  . ARG A 1 240 ? -50.962 -28.614 43.585  1   82.39  ? 410 ARG D CB  1 
ATOM   1927 C  CG  . ARG A 1 240 ? -51.221 -29.185 42.199  1   80.35  ? 410 ARG D CG  1 
ATOM   1928 C  CD  . ARG A 1 240 ? -51.282 -30.699 42.264  1   85.61  ? 410 ARG D CD  1 
ATOM   1929 N  NE  . ARG A 1 240 ? -52.536 -31.223 42.821  1   89.64  ? 410 ARG D NE  1 
ATOM   1930 C  CZ  . ARG A 1 240 ? -52.638 -31.954 43.926  1   91.43  ? 410 ARG D CZ  1 
ATOM   1931 N  NH1 . ARG A 1 240 ? -53.79  -32.512 44.261  1   93.98  ? 410 ARG D NH1 1 
ATOM   1932 N  NH2 . ARG A 1 240 ? -51.575 -32.163 44.678  1   90.35  ? 410 ARG D NH2 1 
ATOM   1933 N  N   . GLU A 1 241 ? -50.253 -26.777 45.979  1   82.59  ? 411 GLU D N   1 
ATOM   1934 C  CA  . GLU A 1 241 ? -50.293 -26.372 47.382  1   85.38  ? 411 GLU D CA  1 
ATOM   1935 C  C   . GLU A 1 241 ? -50.936 -24.991 47.514  1   85.29  ? 411 GLU D C   1 
ATOM   1936 O  O   . GLU A 1 241 ? -51.904 -24.813 48.263  1   87.76  ? 411 GLU D O   1 
ATOM   1937 C  CB  . GLU A 1 241 ? -48.917 -26.364 48.06   1   84.61  ? 411 GLU D CB  1 
ATOM   1938 C  CG  . GLU A 1 241 ? -48.513 -27.686 48.713  1   89.25  ? 411 GLU D CG  1 
ATOM   1939 C  CD  . GLU A 1 241 ? -49.646 -28.361 49.481  1   100.22 ? 411 GLU D CD  1 
ATOM   1940 O  OE1 . GLU A 1 241 ? -50.256 -27.673 50.335  1   104.67 ? 411 GLU D OE1 1 
ATOM   1941 O  OE2 . GLU A 1 241 ? -49.949 -29.553 49.215  1   99.96  ? 411 GLU D OE2 1 
ATOM   1942 N  N   . LYS A 1 242 ? -50.392 -24.045 46.734  1   82.06  ? 412 LYS D N   1 
ATOM   1943 C  CA  . LYS A 1 242 ? -50.764 -22.636 46.721  1   80.89  ? 412 LYS D CA  1 
ATOM   1944 C  C   . LYS A 1 242 ? -52.221 -22.437 46.307  1   81.83  ? 412 LYS D C   1 
ATOM   1945 O  O   . LYS A 1 242 ? -52.869 -21.546 46.842  1   82.92  ? 412 LYS D O   1 
ATOM   1946 C  CB  . LYS A 1 242 ? -49.84  -21.853 45.778  1   75.94  ? 412 LYS D CB  1 
ATOM   1947 C  CG  . LYS A 1 242 ? -50.355 -20.526 45.249  1   71.71  ? 412 LYS D CG  1 
ATOM   1948 C  CD  . LYS A 1 242 ? -49.351 -19.857 44.321  1   66.75  ? 412 LYS D CD  1 
ATOM   1949 C  CE  . LYS A 1 242 ? -49.792 -18.551 43.715  1   64.17  ? 412 LYS D CE  1 
ATOM   1950 N  NZ  . LYS A 1 242 ? -48.804 -18     42.778  1   56.35  ? 412 LYS D NZ  1 
ATOM   1951 N  N   . TYR A 1 243 ? -52.72  -23.244 45.36   1   81.7   ? 413 TYR D N   1 
ATOM   1952 C  CA  . TYR A 1 243 ? -54.068 -23.051 44.836  1   85.92  ? 413 TYR D CA  1 
ATOM   1953 C  C   . TYR A 1 243 ? -55.101 -23.926 45.555  1   89.51  ? 413 TYR D C   1 
ATOM   1954 O  O   . TYR A 1 243 ? -56.226 -24.081 45.082  1   86.97  ? 413 TYR D O   1 
ATOM   1955 C  CB  . TYR A 1 243 ? -54.103 -23.254 43.319  1   87.39  ? 413 TYR D CB  1 
ATOM   1956 C  CG  . TYR A 1 243 ? -53.611 -22.073 42.5    1   88.23  ? 413 TYR D CG  1 
ATOM   1957 C  CD1 . TYR A 1 243 ? -52.248 -21.824 42.347  1   90.66  ? 413 TYR D CD1 1 
ATOM   1958 C  CD2 . TYR A 1 243 ? -54.504 -21.218 41.864  1   89.37  ? 413 TYR D CD2 1 
ATOM   1959 C  CE1 . TYR A 1 243 ? -51.787 -20.753 41.595  1   84.79  ? 413 TYR D CE1 1 
ATOM   1960 C  CE2 . TYR A 1 243 ? -54.055 -20.134 41.12   1   88.01  ? 413 TYR D CE2 1 
ATOM   1961 C  CZ  . TYR A 1 243 ? -52.694 -19.908 40.981  1   86.61  ? 413 TYR D CZ  1 
ATOM   1962 O  OH  . TYR A 1 243 ? -52.238 -18.861 40.24   1   84.27  ? 413 TYR D OH  1 
ATOM   1963 N  N   . LYS A 1 244 ? -54.72  -24.47  46.706  1   93.59  ? 414 LYS D N   1 
ATOM   1964 C  CA  . LYS A 1 244 ? -55.68  -25.239 47.528  1   97.64  ? 414 LYS D CA  1 
ATOM   1965 C  C   . LYS A 1 244 ? -56.246 -24.28  48.569  1   99.37  ? 414 LYS D C   1 
ATOM   1966 O  O   . LYS A 1 244 ? -56.985 -24.737 49.461  1   101.18 ? 414 LYS D O   1 
ATOM   1967 C  CB  . LYS A 1 244 ? -54.96  -26.355 48.286  1   100.84 ? 414 LYS D CB  1 
ATOM   1968 C  CG  . LYS A 1 244 ? -54.854 -27.702 47.6    1   103.09 ? 414 LYS D CG  1 
ATOM   1969 C  CD  . LYS A 1 244 ? -53.683 -28.536 48.104  1   105.59 ? 414 LYS D CD  1 
ATOM   1970 C  CE  . LYS A 1 244 ? -53.217 -29.512 47.075  1   108.57 ? 414 LYS D CE  1 
ATOM   1971 N  NZ  . LYS A 1 244 ? -51.777 -29.757 47.179  1   110.11 ? 414 LYS D NZ  1 
ATOM   1972 N  N   . ASN A 1 245 ? -55.902 -22.999 48.459  1   101.07 ? 415 ASN D N   1 
ATOM   1973 C  CA  . ASN A 1 245 ? -56.314 -22.035 49.512  1   107.17 ? 415 ASN D CA  1 
ATOM   1974 C  C   . ASN A 1 245 ? -57.497 -21.2   49.028  1   107.9  ? 415 ASN D C   1 
ATOM   1975 O  O   . ASN A 1 245 ? -57.757 -21.181 47.81   1   105.62 ? 415 ASN D O   1 
ATOM   1976 C  CB  . ASN A 1 245 ? -55.13  -21.197 49.97   1   109.88 ? 415 ASN D CB  1 
ATOM   1977 C  CG  . ASN A 1 245 ? -53.981 -22.063 50.424  1   114.17 ? 415 ASN D CG  1 
ATOM   1978 O  OD1 . ASN A 1 245 ? -54.039 -22.654 51.508  1   118.97 ? 415 ASN D OD1 1 
ATOM   1979 N  ND2 . ASN A 1 245 ? -52.937 -22.16  49.615  1   110.8  ? 415 ASN D ND2 1 
ATOM   1980 N  N   . SER A 1 246 ? -58.172 -20.527 49.958  1   108.95 ? 416 SER D N   1 
ATOM   1981 C  CA  . SER A 1 246 ? -59.392 -19.762 49.606  1   108.23 ? 416 SER D CA  1 
ATOM   1982 C  C   . SER A 1 246 ? -59.078 -18.674 48.579  1   105.7  ? 416 SER D C   1 
ATOM   1983 O  O   . SER A 1 246 ? -59.901 -18.475 47.669  1   105.5  ? 416 SER D O   1 
ATOM   1984 C  CB  . SER A 1 246 ? -59.998 -19.158 50.825  1   110.36 ? 416 SER D CB  1 
ATOM   1985 O  OG  . SER A 1 246 ? -60.89  -18.112 50.468  1   115.64 ? 416 SER D OG  1 
ATOM   1986 N  N   . LYS A 1 247 ? -57.949 -17.985 48.732  1   99.34  ? 417 LYS D N   1 
ATOM   1987 C  CA  . LYS A 1 247 ? -57.63  -16.862 47.818  1   97.66  ? 417 LYS D CA  1 
ATOM   1988 C  C   . LYS A 1 247 ? -57.905 -17.304 46.379  1   96.83  ? 417 LYS D C   1 
ATOM   1989 O  O   . LYS A 1 247 ? -58.415 -16.481 45.599  1   90.43  ? 417 LYS D O   1 
ATOM   1990 C  CB  . LYS A 1 247 ? -56.169 -16.441 48.002  1   98.3   ? 417 LYS D CB  1 
ATOM   1991 C  CG  . LYS A 1 247 ? -55.641 -15.44  46.987  1   95.95  ? 417 LYS D CG  1 
ATOM   1992 C  CD  . LYS A 1 247 ? -54.303 -14.834 47.387  1   98.1   ? 417 LYS D CD  1 
ATOM   1993 C  CE  . LYS A 1 247 ? -53.574 -15.683 48.375  1   101.16 ? 417 LYS D CE  1 
ATOM   1994 N  NZ  . LYS A 1 247 ? -52.188 -15.241 48.544  1   101.51 ? 417 LYS D NZ  1 
ATOM   1995 N  N   . TYR A 1 248 ? -57.593 -18.561 46.06   1   101.24 ? 418 TYR D N   1 
ATOM   1996 C  CA  . TYR A 1 248 ? -57.769 -19.074 44.676  1   103.12 ? 418 TYR D CA  1 
ATOM   1997 C  C   . TYR A 1 248 ? -58.891 -20.101 44.657  1   106.79 ? 418 TYR D C   1 
ATOM   1998 O  O   . TYR A 1 248 ? -58.987 -20.846 43.667  1   108.3  ? 418 TYR D O   1 
ATOM   1999 C  CB  . TYR A 1 248 ? -56.436 -19.645 44.189  1   96.48  ? 418 TYR D CB  1 
ATOM   2000 C  CG  . TYR A 1 248 ? -55.238 -18.725 44.363  1   94.23  ? 418 TYR D CG  1 
ATOM   2001 C  CD1 . TYR A 1 248 ? -55.099 -17.576 43.598  1   93.64  ? 418 TYR D CD1 1 
ATOM   2002 C  CD2 . TYR A 1 248 ? -54.245 -19.01  45.29   1   92.43  ? 418 TYR D CD2 1 
ATOM   2003 C  CE1 . TYR A 1 248 ? -54.01  -16.736 43.75   1   92.65  ? 418 TYR D CE1 1 
ATOM   2004 C  CE2 . TYR A 1 248 ? -53.153 -18.178 45.454  1   94.26  ? 418 TYR D CE2 1 
ATOM   2005 C  CZ  . TYR A 1 248 ? -53.033 -17.038 44.68   1   96.02  ? 418 TYR D CZ  1 
ATOM   2006 O  OH  . TYR A 1 248 ? -51.959 -16.213 44.838  1   91.58  ? 418 TYR D OH  1 
ATOM   2007 N  N   . HIS A 1 249 ? -59.701 -20.151 45.714  1   109.13 ? 419 HIS D N   1 
ATOM   2008 C  CA  . HIS A 1 249 ? -60.887 -21.05  45.736  1   116.38 ? 419 HIS D CA  1 
ATOM   2009 C  C   . HIS A 1 249 ? -60.512 -22.484 45.362  1   112.22 ? 419 HIS D C   1 
ATOM   2010 O  O   . HIS A 1 249 ? -61.068 -22.991 44.37   1   109.78 ? 419 HIS D O   1 
ATOM   2011 C  CB  . HIS A 1 249 ? -61.97  -20.534 44.783  1   124.75 ? 419 HIS D CB  1 
ATOM   2012 C  CG  . HIS A 1 249 ? -61.953 -19.058 44.574  1   129.5  ? 419 HIS D CG  1 
ATOM   2013 N  ND1 . HIS A 1 249 ? -61.943 -18.149 45.609  1   133.22 ? 419 HIS D ND1 1 
ATOM   2014 C  CD2 . HIS A 1 249 ? -61.943 -18.34  43.449  1   126.34 ? 419 HIS D CD2 1 
ATOM   2015 C  CE1 . HIS A 1 249 ? -61.927 -16.924 45.11   1   129.86 ? 419 HIS D CE1 1 
ATOM   2016 N  NE2 . HIS A 1 249 ? -61.926 -17.017 43.799  1   130.83 ? 419 HIS D NE2 1 
ATOM   2017 N  N   . GLY A 1 250 ? -59.613 -23.112 46.127  1   109.92 ? 420 GLY D N   1 
ATOM   2018 C  CA  . GLY A 1 250 ? -59.219 -24.52  45.895  1   110.41 ? 420 GLY D CA  1 
ATOM   2019 C  C   . GLY A 1 250 ? -59.59  -25.044 44.519  1   109.3  ? 420 GLY D C   1 
ATOM   2020 O  O   . GLY A 1 250 ? -60.271 -26.089 44.456  1   112.39 ? 420 GLY D O   1 
ATOM   2021 N  N   . VAL A 1 251 ? -59.155 -24.371 43.45   1   103.76 ? 421 VAL D N   1 
ATOM   2022 C  CA  . VAL A 1 251 ? -59.402 -24.889 42.075  1   101.56 ? 421 VAL D CA  1 
ATOM   2023 C  C   . VAL A 1 251 ? -58.415 -26.035 41.825  1   100.01 ? 421 VAL D C   1 
ATOM   2024 O  O   . VAL A 1 251 ? -58.62  -26.804 40.869  1   101.15 ? 421 VAL D O   1 
ATOM   2025 C  CB  . VAL A 1 251 ? -59.257 -23.778 41.024  1   98.69  ? 421 VAL D CB  1 
ATOM   2026 C  CG1 . VAL A 1 251 ? -60.472 -22.863 41.007  1   101.48 ? 421 VAL D CG1 1 
ATOM   2027 C  CG2 . VAL A 1 251 ? -57.979 -22.973 41.229  1   95.68  ? 421 VAL D CG2 1 
ATOM   2028 N  N   . SER A 1 252 ? -57.387 -26.134 42.66   1   95.29  ? 422 SER D N   1 
ATOM   2029 C  CA  . SER A 1 252 ? -56.413 -27.24  42.523  1   91.77  ? 422 SER D CA  1 
ATOM   2030 C  C   . SER A 1 252 ? -57.062 -28.521 43.052  1   93.53  ? 422 SER D C   1 
ATOM   2031 O  O   . SER A 1 252 ? -56.579 -29.616 42.706  1   92.35  ? 422 SER D O   1 
ATOM   2032 C  CB  . SER A 1 252 ? -55.139 -26.918 43.243  1   85.64  ? 422 SER D CB  1 
ATOM   2033 O  OG  . SER A 1 252 ? -55.363 -26.833 44.639  1   86.95  ? 422 SER D OG  1 
ATOM   2034 N  N   . LEU A 1 253 ? -58.112 -28.38  43.863  1   95.28  ? 423 LEU D N   1 
ATOM   2035 C  CA  . LEU A 1 253 ? -58.805 -29.538 44.41   1   99.32  ? 423 LEU D CA  1 
ATOM   2036 C  C   . LEU A 1 253 ? -59.794 -30.129 43.407  1   102.18 ? 423 LEU D C   1 
ATOM   2037 O  O   . LEU A 1 253 ? -60.25  -31.253 43.595  1   107.84 ? 423 LEU D O   1 
ATOM   2038 C  CB  . LEU A 1 253 ? -59.485 -29.176 45.727  1   100.74 ? 423 LEU D CB  1 
ATOM   2039 C  CG  . LEU A 1 253 ? -58.544 -28.888 46.902  1   100.11 ? 423 LEU D CG  1 
ATOM   2040 C  CD1 . LEU A 1 253 ? -59.304 -28.395 48.127  1   100.59 ? 423 LEU D CD1 1 
ATOM   2041 C  CD2 . LEU A 1 253 ? -57.69  -30.106 47.259  1   100.27 ? 423 LEU D CD2 1 
ATOM   2042 N  N   . LEU A 1 254 ? -60.116 -29.386 42.345  1   101.59 ? 424 LEU D N   1 
ATOM   2043 C  CA  . LEU A 1 254 ? -61.085 -29.848 41.364  1   106.82 ? 424 LEU D CA  1 
ATOM   2044 C  C   . LEU A 1 254 ? -60.495 -30.97  40.519  1   110.79 ? 424 LEU D C   1 
ATOM   2045 O  O   . LEU A 1 254 ? -59.299 -30.984 40.231  1   113.22 ? 424 LEU D O   1 
ATOM   2046 C  CB  . LEU A 1 254 ? -61.568 -28.689 40.503  1   104.57 ? 424 LEU D CB  1 
ATOM   2047 C  CG  . LEU A 1 254 ? -62.222 -27.555 41.293  1   108.3  ? 424 LEU D CG  1 
ATOM   2048 C  CD1 . LEU A 1 254 ? -62.811 -26.53  40.338  1   109.54 ? 424 LEU D CD1 1 
ATOM   2049 C  CD2 . LEU A 1 254 ? -63.279 -28.113 42.251  1   111.59 ? 424 LEU D CD2 1 
ATOM   2050 N  N   . ASN A 1 255 ? -61.357 -31.931 40.162  1   114.82 ? 425 ASN D N   1 
ATOM   2051 C  CA  . ASN A 1 255 ? -60.985 -33.041 39.301  1   114.98 ? 425 ASN D CA  1 
ATOM   2052 C  C   . ASN A 1 255 ? -61.055 -32.555 37.857  1   112.95 ? 425 ASN D C   1 
ATOM   2053 O  O   . ASN A 1 255 ? -62.083 -32.039 37.433  1   116.3  ? 425 ASN D O   1 
ATOM   2054 C  CB  . ASN A 1 255 ? -61.876 -34.264 39.515  1   122.02 ? 425 ASN D CB  1 
ATOM   2055 C  CG  . ASN A 1 255 ? -62.078 -34.621 40.971  1   124.74 ? 425 ASN D CG  1 
ATOM   2056 O  OD1 . ASN A 1 255 ? -63.17  -35.051 41.361  1   128.08 ? 425 ASN D OD1 1 
ATOM   2057 N  ND2 . ASN A 1 255 ? -61.036 -34.488 41.782  1   123.05 ? 425 ASN D ND2 1 
ATOM   2058 N  N   . PRO A 1 256 ? -59.968 -32.687 37.06   1   109.35 ? 426 PRO D N   1 
ATOM   2059 C  CA  . PRO A 1 256 ? -59.989 -32.275 35.651  1   105.69 ? 426 PRO D CA  1 
ATOM   2060 C  C   . PRO A 1 256 ? -60.928 -33.123 34.797  1   109.23 ? 426 PRO D C   1 
ATOM   2061 O  O   . PRO A 1 256 ? -61.137 -34.299 35.09   1   110.7  ? 426 PRO D O   1 
ATOM   2062 C  CB  . PRO A 1 256 ? -58.527 -32.483 35.226  1   102.42 ? 426 PRO D CB  1 
ATOM   2063 C  CG  . PRO A 1 256 ? -58.02  -33.583 36.138  1   103.56 ? 426 PRO D CG  1 
ATOM   2064 C  CD  . PRO A 1 256 ? -58.672 -33.259 37.469  1   106.39 ? 426 PRO D CD  1 
ATOM   2065 N  N   . PRO A 1 257 ? -61.476 -32.578 33.686  1   108.59 ? 427 PRO D N   1 
ATOM   2066 C  CA  . PRO A 1 257 ? -62.346 -33.346 32.796  1   112.45 ? 427 PRO D CA  1 
ATOM   2067 C  C   . PRO A 1 257 ? -61.565 -34.477 32.131  1   115.64 ? 427 PRO D C   1 
ATOM   2068 O  O   . PRO A 1 257 ? -60.351 -34.584 32.329  1   118.59 ? 427 PRO D O   1 
ATOM   2069 C  CB  . PRO A 1 257 ? -62.844 -32.311 31.79   1   111.49 ? 427 PRO D CB  1 
ATOM   2070 C  CG  . PRO A 1 257 ? -61.757 -31.273 31.776  1   108.12 ? 427 PRO D CG  1 
ATOM   2071 C  CD  . PRO A 1 257 ? -61.248 -31.209 33.205  1   106.07 ? 427 PRO D CD  1 
ATOM   2072 N  N   . GLU A 1 258 ? -62.276 -35.303 31.349  1   115.7  ? 428 GLU D N   1 
ATOM   2073 C  CA  . GLU A 1 258 ? -61.736 -36.533 30.791  1   110.83 ? 428 GLU D CA  1 
ATOM   2074 C  C   . GLU A 1 258 ? -61.193 -36.293 29.383  1   105.24 ? 428 GLU D C   1 
ATOM   2075 O  O   . GLU A 1 258 ? -60.17  -36.885 29.045  1   102.58 ? 428 GLU D O   1 
ATOM   2076 C  CB  . GLU A 1 258 ? -62.787 -37.643 30.807  1   123.91 ? 428 GLU D CB  1 
ATOM   2077 C  CG  . GLU A 1 258 ? -63.399 -37.882 32.186  1   127.64 ? 428 GLU D CG  1 
ATOM   2078 C  CD  . GLU A 1 258 ? -64.239 -36.734 32.723  1   127.81 ? 428 GLU D CD  1 
ATOM   2079 O  OE1 . GLU A 1 258 ? -64.617 -35.835 31.942  1   122.88 ? 428 GLU D OE1 1 
ATOM   2080 O  OE2 . GLU A 1 258 ? -64.493 -36.724 33.943  1   130.26 ? 428 GLU D OE2 1 
ATOM   2081 N  N   . THR A 1 259 ? -61.886 -35.445 28.588  1   103.79 ? 429 THR D N   1 
ATOM   2082 C  CA  . THR A 1 259 ? -61.488 -34.992 27.252  1   100.7  ? 429 THR D CA  1 
ATOM   2083 C  C   . THR A 1 259 ? -62.516 -34.023 26.682  1   99.12  ? 429 THR D C   1 
ATOM   2084 O  O   . THR A 1 259 ? -62.612 -32.91  27.192  1   95.27  ? 429 THR D O   1 
ATOM   2085 C  CB  . THR A 1 259 ? -61.285 -36.147 26.263  1   105.27 ? 429 THR D CB  1 
ATOM   2086 O  OG1 . THR A 1 259 ? -62.255 -37.157 26.557  1   111.03 ? 429 THR D OG1 1 
ATOM   2087 C  CG2 . THR A 1 259 ? -59.848 -36.639 26.181  1   100.68 ? 429 THR D CG2 1 
ATOM   2088 N  N   . GLY B 2 1   ? -22.581 -6.601  23.853  1   115.45 ? -3  GLY A N   1 
ATOM   2089 C  CA  . GLY B 2 1   ? -21.368 -6.815  24.663  1   113.22 ? -3  GLY A CA  1 
ATOM   2090 C  C   . GLY B 2 1   ? -21.732 -6.975  26.133  1   117.29 ? -3  GLY A C   1 
ATOM   2091 O  O   . GLY B 2 1   ? -21.511 -6.046  26.915  1   127.67 ? -3  GLY A O   1 
ATOM   2092 N  N   . PRO B 2 2   ? -22.319 -8.135  26.534  1   116.92 ? -2  PRO A N   1 
ATOM   2093 C  CA  . PRO B 2 2   ? -22.788 -8.343  27.911  1   115.91 ? -2  PRO A CA  1 
ATOM   2094 C  C   . PRO B 2 2   ? -21.79  -8.183  29.06   1   114.82 ? -2  PRO A C   1 
ATOM   2095 O  O   . PRO B 2 2   ? -22.121 -7.605  30.089  1   117.33 ? -2  PRO A O   1 
ATOM   2096 C  CB  . PRO B 2 2   ? -23.376 -9.782  27.899  1   120.99 ? -2  PRO A CB  1 
ATOM   2097 C  CG  . PRO B 2 2   ? -22.768 -10.462 26.687  1   115.04 ? -2  PRO A CG  1 
ATOM   2098 C  CD  . PRO B 2 2   ? -22.563 -9.323  25.689  1   117.78 ? -2  PRO A CD  1 
ATOM   2099 N  N   . GLY B 2 3   ? -20.577 -8.704  28.907  1   116.66 ? -1  GLY A N   1 
ATOM   2100 C  CA  . GLY B 2 3   ? -19.682 -8.791  30.077  1   108.79 ? -1  GLY A CA  1 
ATOM   2101 C  C   . GLY B 2 3   ? -18.69  -7.695  30.371  1   101.19 ? -1  GLY A C   1 
ATOM   2102 O  O   . GLY B 2 3   ? -18.583 -6.746  29.574  1   95.35  ? -1  GLY A O   1 
ATOM   2103 N  N   . SER B 2 4   ? -18.008 -7.839  31.511  1   107.85 ? 0   SER A N   1 
ATOM   2104 C  CA  . SER B 2 4   ? -16.96  -6.889  31.951  1   101.46 ? 0   SER A CA  1 
ATOM   2105 C  C   . SER B 2 4   ? -15.844 -7.732  32.572  1   91.12  ? 0   SER A C   1 
ATOM   2106 O  O   . SER B 2 4   ? -16.142 -8.857  33.005  1   88.56  ? 0   SER A O   1 
ATOM   2107 C  CB  . SER B 2 4   ? -17.504 -5.912  32.938  1   100.57 ? 0   SER A CB  1 
ATOM   2108 O  OG  . SER B 2 4   ? -17.118 -6.265  34.259  1   109.16 ? 0   SER A OG  1 
ATOM   2109 N  N   . MET B 2 5   ? -14.628 -7.202  32.662  1   84.53  ? 1   MET A N   1 
ATOM   2110 C  CA  . MET B 2 5   ? -13.479 -8.015  33.143  1   77.47  ? 1   MET A CA  1 
ATOM   2111 C  C   . MET B 2 5   ? -13.545 -8.239  34.657  1   74.68  ? 1   MET A C   1 
ATOM   2112 O  O   . MET B 2 5   ? -12.719 -9.007  35.166  1   73.03  ? 1   MET A O   1 
ATOM   2113 C  CB  . MET B 2 5   ? -12.163 -7.324  32.78   1   76.14  ? 1   MET A CB  1 
ATOM   2114 C  CG  . MET B 2 5   ? -11.89  -7.294  31.297  1   72.16  ? 1   MET A CG  1 
ATOM   2115 S  SD  . MET B 2 5   ? -12.398 -8.865  30.578  1   71.91  ? 1   MET A SD  1 
ATOM   2116 C  CE  . MET B 2 5   ? -10.976 -9.864  31.03   1   66.55  ? 1   MET A CE  1 
ATOM   2117 N  N   . GLU B 2 6   ? -14.495 -7.607  35.337  1   76.89  ? 2   GLU A N   1 
ATOM   2118 C  CA  . GLU B 2 6   ? -14.578 -7.71   36.815  1   78.51  ? 2   GLU A CA  1 
ATOM   2119 C  C   . GLU B 2 6   ? -15.262 -9.02   37.219  1   73.33  ? 2   GLU A C   1 
ATOM   2120 O  O   . GLU B 2 6   ? -15.133 -9.402  38.387  1   73.51  ? 2   GLU A O   1 
ATOM   2121 C  CB  . GLU B 2 6   ? -15.354 -6.525  37.383  1   84     ? 2   GLU A CB  1 
ATOM   2122 C  CG  . GLU B 2 6   ? -14.532 -5.677  38.348  1   98.3   ? 2   GLU A CG  1 
ATOM   2123 C  CD  . GLU B 2 6   ? -14.144 -6.394  39.628  1   103.63 ? 2   GLU A CD  1 
ATOM   2124 O  OE1 . GLU B 2 6   ? -15.057 -6.803  40.374  1   105.64 ? 2   GLU A OE1 1 
ATOM   2125 O  OE2 . GLU B 2 6   ? -12.93  -6.543  39.876  1   101.83 ? 2   GLU A OE2 1 
ATOM   2126 N  N   . ASN B 2 7   ? -15.967 -9.661  36.292  1   67.75  ? 3   ASN A N   1 
ATOM   2127 C  CA  . ASN B 2 7   ? -16.581 -10.938 36.617  1   66.79  ? 3   ASN A CA  1 
ATOM   2128 C  C   . ASN B 2 7   ? -15.738 -12.11  36.12   1   64.93  ? 3   ASN A C   1 
ATOM   2129 O  O   . ASN B 2 7   ? -16.233 -13.234 36.126  1   64.73  ? 3   ASN A O   1 
ATOM   2130 C  CB  . ASN B 2 7   ? -17.963 -11.143 36      1   67.97  ? 3   ASN A CB  1 
ATOM   2131 C  CG  . ASN B 2 7   ? -18.929 -10.012 36.273  1   74.28  ? 3   ASN A CG  1 
ATOM   2132 O  OD1 . ASN B 2 7   ? -19.106 -9.591  37.431  1   76.66  ? 3   ASN A OD1 1 
ATOM   2133 N  ND2 . ASN B 2 7   ? -19.568 -9.523  35.21   1   74.9   ? 3   ASN A ND2 1 
ATOM   2134 N  N   . PHE B 2 8   ? -14.509 -11.857 35.638  1   62.15  ? 4   PHE A N   1 
ATOM   2135 C  CA  . PHE B 2 8   ? -13.581 -12.934 35.318  1   59.77  ? 4   PHE A CA  1 
ATOM   2136 C  C   . PHE B 2 8   ? -12.481 -13.056 36.382  1   64.06  ? 4   PHE A C   1 
ATOM   2137 O  O   . PHE B 2 8   ? -11.936 -12.062 36.869  1   67.78  ? 4   PHE A O   1 
ATOM   2138 C  CB  . PHE B 2 8   ? -13.077 -12.755 33.895  1   55.78  ? 4   PHE A CB  1 
ATOM   2139 C  CG  . PHE B 2 8   ? -14.201 -12.9   32.884  1   54.26  ? 4   PHE A CG  1 
ATOM   2140 C  CD1 . PHE B 2 8   ? -14.706 -14.159 32.556  1   52.39  ? 4   PHE A CD1 1 
ATOM   2141 C  CD2 . PHE B 2 8   ? -14.748 -11.786 32.244  1   53.79  ? 4   PHE A CD2 1 
ATOM   2142 C  CE1 . PHE B 2 8   ? -15.734 -14.289 31.623  1   50.31  ? 4   PHE A CE1 1 
ATOM   2143 C  CE2 . PHE B 2 8   ? -15.769 -11.926 31.308  1   51.41  ? 4   PHE A CE2 1 
ATOM   2144 C  CZ  . PHE B 2 8   ? -16.267 -13.174 30.997  1   49.69  ? 4   PHE A CZ  1 
ATOM   2145 N  N   . GLN B 2 9   ? -12.186 -14.301 36.769  1   63.6   ? 5   GLN A N   1 
ATOM   2146 C  CA  . GLN B 2 9   ? -11.039 -14.639 37.594  1   66.48  ? 5   GLN A CA  1 
ATOM   2147 C  C   . GLN B 2 9   ? -10.03  -15.366 36.707  1   64.13  ? 5   GLN A C   1 
ATOM   2148 O  O   . GLN B 2 9   ? -10.36  -16.419 36.173  1   62.31  ? 5   GLN A O   1 
ATOM   2149 C  CB  . GLN B 2 9   ? -11.479 -15.554 38.738  1   70.11  ? 5   GLN A CB  1 
ATOM   2150 C  CG  . GLN B 2 9   ? -10.368 -15.908 39.724  1   77.92  ? 5   GLN A CG  1 
ATOM   2151 C  CD  . GLN B 2 9   ? -9.877  -14.725 40.531  1   88.55  ? 5   GLN A CD  1 
ATOM   2152 O  OE1 . GLN B 2 9   ? -10.474 -14.338 41.542  1   100.21 ? 5   GLN A OE1 1 
ATOM   2153 N  NE2 . GLN B 2 9   ? -8.779  -14.125 40.09   1   89.9   ? 5   GLN A NE2 1 
ATOM   2154 N  N   . LYS B 2 10  ? -8.837  -14.779 36.499  1   65.36  ? 6   LYS A N   1 
ATOM   2155 C  CA  . LYS B 2 10  ? -7.78   -15.433 35.738  1   67.58  ? 6   LYS A CA  1 
ATOM   2156 C  C   . LYS B 2 10  ? -7.341  -16.707 36.455  1   68.53  ? 6   LYS A C   1 
ATOM   2157 O  O   . LYS B 2 10  ? -7.294  -16.733 37.684  1   68.66  ? 6   LYS A O   1 
ATOM   2158 C  CB  . LYS B 2 10  ? -6.515  -14.586 35.656  1   72.85  ? 6   LYS A CB  1 
ATOM   2159 C  CG  . LYS B 2 10  ? -6.281  -13.795 34.391  1   81.08  ? 6   LYS A CG  1 
ATOM   2160 C  CD  . LYS B 2 10  ? -4.81   -13.375 34.212  1   87.55  ? 6   LYS A CD  1 
ATOM   2161 C  CE  . LYS B 2 10  ? -4.228  -12.389 35.199  1   89.52  ? 6   LYS A CE  1 
ATOM   2162 N  NZ  . LYS B 2 10  ? -2.859  -12.04  34.826  1   90.71  ? 6   LYS A NZ  1 
ATOM   2163 N  N   . VAL B 2 11  ? -7.001  -17.747 35.681  1   67.32  ? 7   VAL A N   1 
ATOM   2164 C  CA  . VAL B 2 11  ? -6.667  -19.023 36.292  1   71.81  ? 7   VAL A CA  1 
ATOM   2165 C  C   . VAL B 2 11  ? -5.22   -19.377 35.968  1   73.1   ? 7   VAL A C   1 
ATOM   2166 O  O   . VAL B 2 11  ? -4.435  -19.652 36.867  1   81.35  ? 7   VAL A O   1 
ATOM   2167 C  CB  . VAL B 2 11  ? -7.628  -20.179 35.948  1   71.39  ? 7   VAL A CB  1 
ATOM   2168 C  CG1 . VAL B 2 11  ? -6.969  -21.538 36.154  1   69.88  ? 7   VAL A CG1 1 
ATOM   2169 C  CG2 . VAL B 2 11  ? -8.944  -20.084 36.713  1   67.86  ? 7   VAL A CG2 1 
ATOM   2170 N  N   . GLU B 2 12  ? -4.881  -19.379 34.68   1   69.39  ? 8   GLU A N   1 
ATOM   2171 C  CA  . GLU B 2 12  ? -3.512  -19.64  34.283  1   73.01  ? 8   GLU A CA  1 
ATOM   2172 C  C   . GLU B 2 12  ? -3.346  -19.262 32.813  1   73.58  ? 8   GLU A C   1 
ATOM   2173 O  O   . GLU B 2 12  ? -4.334  -19.158 32.084  1   75.46  ? 8   GLU A O   1 
ATOM   2174 C  CB  . GLU B 2 12  ? -3.178  -21.103 34.58   1   74.02  ? 8   GLU A CB  1 
ATOM   2175 C  CG  . GLU B 2 12  ? -3.519  -22.073 33.455  1   75.24  ? 8   GLU A CG  1 
ATOM   2176 C  CD  . GLU B 2 12  ? -3.779  -23.515 33.848  1   79.47  ? 8   GLU A CD  1 
ATOM   2177 O  OE1 . GLU B 2 12  ? -3.958  -23.803 35.055  1   82.63  ? 8   GLU A OE1 1 
ATOM   2178 O  OE2 . GLU B 2 12  ? -3.799  -24.353 32.918  1   78.89  ? 8   GLU A OE2 1 
ATOM   2179 N  N   . LYS B 2 13  ? -2.094  -19.043 32.391  1   70.7   ? 9   LYS A N   1 
ATOM   2180 C  CA  . LYS B 2 13  ? -1.782  -18.865 30.988  1   69.53  ? 9   LYS A CA  1 
ATOM   2181 C  C   . LYS B 2 13  ? -1.941  -20.222 30.312  1   66.63  ? 9   LYS A C   1 
ATOM   2182 O  O   . LYS B 2 13  ? -1.632  -21.243 30.923  1   67.81  ? 9   LYS A O   1 
ATOM   2183 C  CB  . LYS B 2 13  ? -0.362  -18.301 30.869  1   77.45  ? 9   LYS A CB  1 
ATOM   2184 C  CG  . LYS B 2 13  ? 0.183   -18.223 29.451  1   86.55  ? 9   LYS A CG  1 
ATOM   2185 C  CD  . LYS B 2 13  ? 1.706   -18.255 29.363  1   98.88  ? 9   LYS A CD  1 
ATOM   2186 C  CE  . LYS B 2 13  ? 2.228   -18.744 28.033  1   102.67 ? 9   LYS A CE  1 
ATOM   2187 N  NZ  . LYS B 2 13  ? 2.625   -17.676 27.113  1   100.61 ? 9   LYS A NZ  1 
ATOM   2188 N  N   . ILE B 2 14  ? -2.449  -20.228 29.071  1   62.98  ? 10  ILE A N   1 
ATOM   2189 C  CA  . ILE B 2 14  ? -2.637  -21.473 28.35   1   62.72  ? 10  ILE A CA  1 
ATOM   2190 C  C   . ILE B 2 14  ? -2.089  -21.399 26.933  1   67.68  ? 10  ILE A C   1 
ATOM   2191 O  O   . ILE B 2 14  ? -2.276  -22.347 26.16   1   74.86  ? 10  ILE A O   1 
ATOM   2192 C  CB  . ILE B 2 14  ? -4.111  -21.908 28.319  1   62.56  ? 10  ILE A CB  1 
ATOM   2193 C  CG1 . ILE B 2 14  ? -5.059  -20.766 27.986  1   61.56  ? 10  ILE A CG1 1 
ATOM   2194 C  CG2 . ILE B 2 14  ? -4.496  -22.606 29.624  1   72.31  ? 10  ILE A CG2 1 
ATOM   2195 C  CD1 . ILE B 2 14  ? -6.481  -21.214 27.669  1   56.69  ? 10  ILE A CD1 1 
ATOM   2196 N  N   . GLY B 2 15  ? -1.458  -20.284 26.631  1   69.15  ? 11  GLY A N   1 
ATOM   2197 C  CA  . GLY B 2 15  ? -0.874  -20.153 25.308  1   67.73  ? 11  GLY A CA  1 
ATOM   2198 C  C   . GLY B 2 15  ? -0.621  -18.747 24.895  1   71.65  ? 11  GLY A C   1 
ATOM   2199 O  O   . GLY B 2 15  ? -0.858  -17.822 25.674  1   71.43  ? 11  GLY A O   1 
ATOM   2200 N  N   . GLU B 2 16  ? -0.091  -18.627 23.7    1   73.63  ? 12  GLU A N   1 
ATOM   2201 C  CA  . GLU B 2 16  ? 0.212   -17.304 23.137  1   75.82  ? 12  GLU A CA  1 
ATOM   2202 C  C   . GLU B 2 16  ? -0.032  -17.358 21.637  1   77.21  ? 12  GLU A C   1 
ATOM   2203 O  O   . GLU B 2 16  ? 0.244   -18.385 21.014  1   75.6   ? 12  GLU A O   1 
ATOM   2204 C  CB  . GLU B 2 16  ? 1.682   -16.922 23.226  1   73.47  ? 12  GLU A CB  1 
ATOM   2205 C  CG  . GLU B 2 16  ? 2.184   -16.706 24.645  1   71.55  ? 12  GLU A CG  1 
ATOM   2206 C  CD  . GLU B 2 16  ? 3.666   -16.406 24.609  1   71.23  ? 12  GLU A CD  1 
ATOM   2207 O  OE1 . GLU B 2 16  ? 4.263   -16.568 23.523  1   68.73  ? 12  GLU A OE1 1 
ATOM   2208 O  OE2 . GLU B 2 16  ? 4.215   -16.004 25.652  1   71.27  ? 12  GLU A OE2 1 
ATOM   2209 N  N   . GLY B 2 17  ? -0.64   -16.304 21.125  1   84.29  ? 13  GLY A N   1 
ATOM   2210 C  CA  . GLY B 2 17  ? -0.909  -16.239 19.699  1   94.3   ? 13  GLY A CA  1 
ATOM   2211 C  C   . GLY B 2 17  ? -0.464  -14.938 19.087  1   117.95 ? 13  GLY A C   1 
ATOM   2212 O  O   . GLY B 2 17  ? 0.223   -14.162 19.766  1   128.6  ? 13  GLY A O   1 
ATOM   2213 N  N   . THR B 2 18  ? -0.823  -14.728 17.827  1   122.21 ? 14  THR A N   1 
ATOM   2214 C  CA  . THR B 2 18  ? -0.464  -13.528 17.071  1   119.51 ? 14  THR A CA  1 
ATOM   2215 C  C   . THR B 2 18  ? -0.568  -12.294 17.925  1   119.55 ? 14  THR A C   1 
ATOM   2216 O  O   . THR B 2 18  ? 0.359   -11.475 17.857  1   112.66 ? 14  THR A O   1 
ATOM   2217 C  CB  . THR B 2 18  ? -1.467  -13.487 15.913  1   122.74 ? 14  THR A CB  1 
ATOM   2218 O  OG1 . THR B 2 18  ? -1.07   -12.47  15      1   144.37 ? 14  THR A OG1 1 
ATOM   2219 C  CG2 . THR B 2 18  ? -2.872  -13.136 16.366  1   96.73  ? 14  THR A CG2 1 
ATOM   2220 N  N   . TYR B 2 19  ? -1.634  -12.161 18.713  1   117.63 ? 15  TYR A N   1 
ATOM   2221 C  CA  . TYR B 2 19  ? -1.876  -10.894 19.44   1   113.85 ? 15  TYR A CA  1 
ATOM   2222 C  C   . TYR B 2 19  ? -1.327  -10.845 20.817  1   104.06 ? 15  TYR A C   1 
ATOM   2223 O  O   . TYR B 2 19  ? -1.37   -9.767  21.437  1   94.41  ? 15  TYR A O   1 
ATOM   2224 C  CB  . TYR B 2 19  ? -3.371  -10.934 19.708  1   127.41 ? 15  TYR A CB  1 
ATOM   2225 C  CG  . TYR B 2 19  ? -4.252  -11.297 18.525  1   160.06 ? 15  TYR A CG  1 
ATOM   2226 C  CD1 . TYR B 2 19  ? -4.415  -10.432 17.446  1   164.99 ? 15  TYR A CD1 1 
ATOM   2227 C  CD2 . TYR B 2 19  ? -4.984  -12.474 18.534  1   179.34 ? 15  TYR A CD2 1 
ATOM   2228 C  CE1 . TYR B 2 19  ? -5.255  -10.751 16.394  1   174.38 ? 15  TYR A CE1 1 
ATOM   2229 C  CE2 . TYR B 2 19  ? -5.821  -12.803 17.484  1   193.79 ? 15  TYR A CE2 1 
ATOM   2230 C  CZ  . TYR B 2 19  ? -5.957  -11.941 16.415  1   198.44 ? 15  TYR A CZ  1 
ATOM   2231 O  OH  . TYR B 2 19  ? -6.792  -12.304 15.409  1   205.92 ? 15  TYR A OH  1 
ATOM   2232 N  N   . GLY B 2 20  ? -0.886  -11.977 21.332  1   96.57  ? 16  GLY A N   1 
ATOM   2233 C  CA  . GLY B 2 20  ? -0.479  -11.962 22.733  1   87.17  ? 16  GLY A CA  1 
ATOM   2234 C  C   . GLY B 2 20  ? -0.774  -13.243 23.45   1   81.66  ? 16  GLY A C   1 
ATOM   2235 O  O   . GLY B 2 20  ? -0.675  -14.293 22.84   1   81.91  ? 16  GLY A O   1 
ATOM   2236 N  N   . VAL B 2 21  ? -1.168  -13.132 24.703  1   80.96  ? 17  VAL A N   1 
ATOM   2237 C  CA  . VAL B 2 21  ? -1.353  -14.346 25.54   1   81.39  ? 17  VAL A CA  1 
ATOM   2238 C  C   . VAL B 2 21  ? -2.821  -14.775 25.6    1   75.38  ? 17  VAL A C   1 
ATOM   2239 O  O   . VAL B 2 21  ? -3.708  -13.941 25.392  1   76.9   ? 17  VAL A O   1 
ATOM   2240 C  CB  . VAL B 2 21  ? -0.803  -13.983 26.934  1   86.83  ? 17  VAL A CB  1 
ATOM   2241 C  CG1 . VAL B 2 21  ? -1.281  -12.61  27.382  1   95.98  ? 17  VAL A CG1 1 
ATOM   2242 C  CG2 . VAL B 2 21  ? -1.043  -15.037 28.004  1   89.89  ? 17  VAL A CG2 1 
ATOM   2243 N  N   . VAL B 2 22  ? -3.03   -16.056 25.834  1   65.15  ? 18  VAL A N   1 
ATOM   2244 C  CA  . VAL B 2 22  ? -4.406  -16.561 26.04   1   60.32  ? 18  VAL A CA  1 
ATOM   2245 C  C   . VAL B 2 22  ? -4.425  -17.043 27.489  1   64.42  ? 18  VAL A C   1 
ATOM   2246 O  O   . VAL B 2 22  ? -3.481  -17.709 27.901  1   70.98  ? 18  VAL A O   1 
ATOM   2247 C  CB  . VAL B 2 22  ? -4.931  -17.628 25.046  1   52.14  ? 18  VAL A CB  1 
ATOM   2248 C  CG1 . VAL B 2 22  ? -6.347  -18.074 25.372  1   49.44  ? 18  VAL A CG1 1 
ATOM   2249 C  CG2 . VAL B 2 22  ? -4.855  -17.14  23.613  1   52.23  ? 18  VAL A CG2 1 
ATOM   2250 N  N   . TYR B 2 23  ? -5.428  -16.617 28.24   1   63.56  ? 19  TYR A N   1 
ATOM   2251 C  CA  . TYR B 2 23  ? -5.618  -17.115 29.589  1   60.42  ? 19  TYR A CA  1 
ATOM   2252 C  C   . TYR B 2 23  ? -6.86   -17.988 29.673  1   57.45  ? 19  TYR A C   1 
ATOM   2253 O  O   . TYR B 2 23  ? -7.822  -17.801 28.943  1   59.83  ? 19  TYR A O   1 
ATOM   2254 C  CB  . TYR B 2 23  ? -5.875  -15.926 30.506  1   66.21  ? 19  TYR A CB  1 
ATOM   2255 C  CG  . TYR B 2 23  ? -4.666  -15.025 30.697  1   77.71  ? 19  TYR A CG  1 
ATOM   2256 C  CD1 . TYR B 2 23  ? -4.414  -13.974 29.818  1   80.25  ? 19  TYR A CD1 1 
ATOM   2257 C  CD2 . TYR B 2 23  ? -3.777  -15.246 31.749  1   82.49  ? 19  TYR A CD2 1 
ATOM   2258 C  CE1 . TYR B 2 23  ? -3.308  -13.16  29.997  1   89.62  ? 19  TYR A CE1 1 
ATOM   2259 C  CE2 . TYR B 2 23  ? -2.677  -14.43  31.945  1   94.82  ? 19  TYR A CE2 1 
ATOM   2260 C  CZ  . TYR B 2 23  ? -2.441  -13.391 31.059  1   104.13 ? 19  TYR A CZ  1 
ATOM   2261 O  OH  . TYR B 2 23  ? -1.34   -12.599 31.258  1   126.46 ? 19  TYR A OH  1 
ATOM   2262 N  N   . LYS B 2 24  ? -6.843  -18.932 30.606  1   55.07  ? 20  LYS A N   1 
ATOM   2263 C  CA  . LYS B 2 24  ? -8.065  -19.563 31.062  1   52.99  ? 20  LYS A CA  1 
ATOM   2264 C  C   . LYS B 2 24  ? -8.604  -18.747 32.231  1   57.31  ? 20  LYS A C   1 
ATOM   2265 O  O   . LYS B 2 24  ? -7.857  -18.342 33.131  1   61.71  ? 20  LYS A O   1 
ATOM   2266 C  CB  . LYS B 2 24  ? -7.783  -21.036 31.371  1   51.46  ? 20  LYS A CB  1 
ATOM   2267 C  CG  . LYS B 2 24  ? -8.654  -21.694 32.423  1   51.19  ? 20  LYS A CG  1 
ATOM   2268 C  CD  . LYS B 2 24  ? -8.451  -23.203 32.409  1   50.79  ? 20  LYS A CD  1 
ATOM   2269 C  CE  . LYS B 2 24  ? -8.829  -23.879 33.686  1   52.95  ? 20  LYS A CE  1 
ATOM   2270 N  NZ  . LYS B 2 24  ? -9.605  -25.095 33.418  1   52.05  ? 20  LYS A NZ  1 
ATOM   2271 N  N   . ALA B 2 25  ? -9.914  -18.485 32.214  1   56.22  ? 21  ALA A N   1 
ATOM   2272 C  CA  . ALA B 2 25  ? -10.509 -17.711 33.294  1   54.74  ? 21  ALA A CA  1 
ATOM   2273 C  C   . ALA B 2 25  ? -11.845 -18.347 33.659  1   52.88  ? 21  ALA A C   1 
ATOM   2274 O  O   . ALA B 2 25  ? -12.314 -19.25  32.977  1   52.74  ? 21  ALA A O   1 
ATOM   2275 C  CB  . ALA B 2 25  ? -10.658 -16.288 32.823  1   54.11  ? 21  ALA A CB  1 
ATOM   2276 N  N   . ARG B 2 26  ? -12.473 -17.842 34.701  1   52.26  ? 22  ARG A N   1 
ATOM   2277 C  CA  . ARG B 2 26  ? -13.711 -18.41  35.177  1   52.84  ? 22  ARG A CA  1 
ATOM   2278 C  C   . ARG B 2 26  ? -14.663 -17.251 35.446  1   52.85  ? 22  ARG A C   1 
ATOM   2279 O  O   . ARG B 2 26  ? -14.292 -16.323 36.158  1   54.05  ? 22  ARG A O   1 
ATOM   2280 C  CB  . ARG B 2 26  ? -13.351 -19.214 36.427  1   56.42  ? 22  ARG A CB  1 
ATOM   2281 C  CG  . ARG B 2 26  ? -14.449 -19.958 37.161  1   61.41  ? 22  ARG A CG  1 
ATOM   2282 C  CD  . ARG B 2 26  ? -13.901 -20.564 38.441  1   70.87  ? 22  ARG A CD  1 
ATOM   2283 N  NE  . ARG B 2 26  ? -13.996 -19.698 39.625  1   84.11  ? 22  ARG A NE  1 
ATOM   2284 C  CZ  . ARG B 2 26  ? -13.006 -19.24  40.41   1   91.5   ? 22  ARG A CZ  1 
ATOM   2285 N  NH1 . ARG B 2 26  ? -13.3   -18.467 41.449  1   89.55  ? 22  ARG A NH1 1 
ATOM   2286 N  NH2 . ARG B 2 26  ? -11.74  -19.558 40.16   1   93.38  ? 22  ARG A NH2 1 
ATOM   2287 N  N   . ASN B 2 27  ? -15.854 -17.296 34.822  1   51.31  ? 23  ASN A N   1 
ATOM   2288 C  CA  . ASN B 2 27  ? -16.94  -16.362 35.103  1   51.5   ? 23  ASN A CA  1 
ATOM   2289 C  C   . ASN B 2 27  ? -17.343 -16.547 36.556  1   53.39  ? 23  ASN A C   1 
ATOM   2290 O  O   . ASN B 2 27  ? -17.619 -17.653 36.972  1   54.51  ? 23  ASN A O   1 
ATOM   2291 C  CB  . ASN B 2 27  ? -18.137 -16.591 34.184  1   49.16  ? 23  ASN A CB  1 
ATOM   2292 C  CG  . ASN B 2 27  ? -19.193 -15.511 34.277  1   49.09  ? 23  ASN A CG  1 
ATOM   2293 O  OD1 . ASN B 2 27  ? -19.574 -15.121 35.382  1   50.56  ? 23  ASN A OD1 1 
ATOM   2294 N  ND2 . ASN B 2 27  ? -19.702 -15.037 33.143  1   47.16  ? 23  ASN A ND2 1 
ATOM   2295 N  N   . LYS B 2 28  ? -17.336 -15.476 37.343  1   55.87  ? 24  LYS A N   1 
ATOM   2296 C  CA  . LYS B 2 28  ? -17.508 -15.619 38.775  1   58.34  ? 24  LYS A CA  1 
ATOM   2297 C  C   . LYS B 2 28  ? -18.978 -15.716 39.16   1   58.8   ? 24  LYS A C   1 
ATOM   2298 O  O   . LYS B 2 28  ? -19.282 -16.046 40.297  1   61.1   ? 24  LYS A O   1 
ATOM   2299 C  CB  . LYS B 2 28  ? -16.933 -14.394 39.481  1   62.46  ? 24  LYS A CB  1 
ATOM   2300 C  CG  . LYS B 2 28  ? -15.437 -14.395 39.702  1   65.31  ? 24  LYS A CG  1 
ATOM   2301 C  CD  . LYS B 2 28  ? -15.044 -13.207 40.599  1   68.63  ? 24  LYS A CD  1 
ATOM   2302 C  CE  . LYS B 2 28  ? -14.408 -12.079 39.825  1   68.52  ? 24  LYS A CE  1 
ATOM   2303 N  NZ  . LYS B 2 28  ? -14.047 -11.014 40.763  1   70.24  ? 24  LYS A NZ  1 
ATOM   2304 N  N   . LEU B 2 29  ? -19.885 -15.392 38.238  1   58.07  ? 25  LEU A N   1 
ATOM   2305 C  CA  . LEU B 2 29  ? -21.308 -15.354 38.546  1   58.78  ? 25  LEU A CA  1 
ATOM   2306 C  C   . LEU B 2 29  ? -21.999 -16.595 37.971  1   57.16  ? 25  LEU A C   1 
ATOM   2307 O  O   . LEU B 2 29  ? -22.928 -17.118 38.593  1   59.17  ? 25  LEU A O   1 
ATOM   2308 C  CB  . LEU B 2 29  ? -21.933 -14.046 38.054  1   57.59  ? 25  LEU A CB  1 
ATOM   2309 C  CG  . LEU B 2 29  ? -21.416 -12.763 38.711  1   58.22  ? 25  LEU A CG  1 
ATOM   2310 C  CD1 . LEU B 2 29  ? -21.874 -11.551 37.925  1   57.67  ? 25  LEU A CD1 1 
ATOM   2311 C  CD2 . LEU B 2 29  ? -21.805 -12.629 40.173  1   60.14  ? 25  LEU A CD2 1 
ATOM   2312 N  N   . THR B 2 30  ? -21.522 -17.077 36.821  1   53.29  ? 26  THR A N   1 
ATOM   2313 C  CA  . THR B 2 30  ? -22.168 -18.181 36.126  1   54.11  ? 26  THR A CA  1 
ATOM   2314 C  C   . THR B 2 30  ? -21.393 -19.487 36.265  1   56.58  ? 26  THR A C   1 
ATOM   2315 O  O   . THR B 2 30  ? -21.999 -20.557 36.092  1   60.33  ? 26  THR A O   1 
ATOM   2316 C  CB  . THR B 2 30  ? -22.393 -17.915 34.635  1   50.45  ? 26  THR A CB  1 
ATOM   2317 O  OG1 . THR B 2 30  ? -21.114 -17.847 34.012  1   48.44  ? 26  THR A OG1 1 
ATOM   2318 C  CG2 . THR B 2 30  ? -23.211 -16.662 34.409  1   50.65  ? 26  THR A CG2 1 
ATOM   2319 N  N   . GLY B 2 31  ? -20.065 -19.393 36.477  1   55.67  ? 27  GLY A N   1 
ATOM   2320 C  CA  . GLY B 2 31  ? -19.179 -20.54  36.661  1   52.73  ? 27  GLY A CA  1 
ATOM   2321 C  C   . GLY B 2 31  ? -18.495 -20.923 35.355  1   50.49  ? 27  GLY A C   1 
ATOM   2322 O  O   . GLY B 2 31  ? -17.623 -21.792 35.298  1   50.12  ? 27  GLY A O   1 
ATOM   2323 N  N   . GLU B 2 32  ? -18.904 -20.257 34.281  1   49.12  ? 28  GLU A N   1 
ATOM   2324 C  CA  . GLU B 2 32  ? -18.442 -20.675 32.972  1   48.13  ? 28  GLU A CA  1 
ATOM   2325 C  C   . GLU B 2 32  ? -16.924 -20.508 32.959  1   49.19  ? 28  GLU A C   1 
ATOM   2326 O  O   . GLU B 2 32  ? -16.402 -19.48  33.39   1   50.22  ? 28  GLU A O   1 
ATOM   2327 C  CB  . GLU B 2 32  ? -19.22  -19.936 31.871  1   46.54  ? 28  GLU A CB  1 
ATOM   2328 C  CG  . GLU B 2 32  ? -19.028 -20.477 30.459  1   43.64  ? 28  GLU A CG  1 
ATOM   2329 C  CD  . GLU B 2 32  ? -19.685 -19.676 29.34   1   44.67  ? 28  GLU A CD  1 
ATOM   2330 O  OE1 . GLU B 2 32  ? -20.125 -18.519 29.581  1   45.61  ? 28  GLU A OE1 1 
ATOM   2331 O  OE2 . GLU B 2 32  ? -19.749 -20.212 28.195  1   44.68  ? 28  GLU A OE2 1 
ATOM   2332 N  N   . VAL B 2 33  ? -16.243 -21.53  32.438  1   48.83  ? 29  VAL A N   1 
ATOM   2333 C  CA  . VAL B 2 33  ? -14.825 -21.479 32.143  1   48.1   ? 29  VAL A CA  1 
ATOM   2334 C  C   . VAL B 2 33  ? -14.635 -21.006 30.711  1   47.79  ? 29  VAL A C   1 
ATOM   2335 O  O   . VAL B 2 33  ? -15.191 -21.596 29.791  1   48.89  ? 29  VAL A O   1 
ATOM   2336 C  CB  . VAL B 2 33  ? -14.173 -22.858 32.34   1   47.14  ? 29  VAL A CB  1 
ATOM   2337 C  CG1 . VAL B 2 33  ? -12.691 -22.809 31.979  1   47.36  ? 29  VAL A CG1 1 
ATOM   2338 C  CG2 . VAL B 2 33  ? -14.375 -23.382 33.758  1   47.12  ? 29  VAL A CG2 1 
ATOM   2339 N  N   . VAL B 2 34  ? -13.795 -19.977 30.542  1   49.2   ? 30  VAL A N   1 
ATOM   2340 C  CA  . VAL B 2 34  ? -13.584 -19.305 29.258  1   46.87  ? 30  VAL A CA  1 
ATOM   2341 C  C   . VAL B 2 34  ? -12.097 -19.261 28.896  1   46.1   ? 30  VAL A C   1 
ATOM   2342 O  O   . VAL B 2 34  ? -11.219 -19.489 29.735  1   47.96  ? 30  VAL A O   1 
ATOM   2343 C  CB  . VAL B 2 34  ? -14.156 -17.869 29.33   1   46.28  ? 30  VAL A CB  1 
ATOM   2344 C  CG1 . VAL B 2 34  ? -15.671 -17.875 29.525  1   43.78  ? 30  VAL A CG1 1 
ATOM   2345 C  CG2 . VAL B 2 34  ? -13.469 -17.036 30.416  1   47.02  ? 30  VAL A CG2 1 
ATOM   2346 N  N   . ALA B 2 35  ? -11.829 -18.989 27.623  1   43.42  ? 31  ALA A N   1 
ATOM   2347 C  CA  . ALA B 2 35  ? -10.498 -18.598 27.185  1   44.93  ? 31  ALA A CA  1 
ATOM   2348 C  C   . ALA B 2 35  ? -10.542 -17.096 26.932  1   46.24  ? 31  ALA A C   1 
ATOM   2349 O  O   . ALA B 2 35  ? -11.425 -16.648 26.207  1   47.24  ? 31  ALA A O   1 
ATOM   2350 C  CB  . ALA B 2 35  ? -10.078 -19.365 25.94   1   40.75  ? 31  ALA A CB  1 
ATOM   2351 N  N   . LEU B 2 36  ? -9.656  -16.331 27.58   1   47.8   ? 32  LEU A N   1 
ATOM   2352 C  CA  . LEU B 2 36  ? -9.545  -14.904 27.315  1   48.6   ? 32  LEU A CA  1 
ATOM   2353 C  C   . LEU B 2 36  ? -8.374  -14.691 26.373  1   50.85  ? 32  LEU A C   1 
ATOM   2354 O  O   . LEU B 2 36  ? -7.268  -15.107 26.696  1   57.21  ? 32  LEU A O   1 
ATOM   2355 C  CB  . LEU B 2 36  ? -9.321  -14.112 28.592  1   48.76  ? 32  LEU A CB  1 
ATOM   2356 C  CG  . LEU B 2 36  ? -10.43  -14.162 29.644  1   49.23  ? 32  LEU A CG  1 
ATOM   2357 C  CD1 . LEU B 2 36  ? -10.053 -13.269 30.806  1   50.39  ? 32  LEU A CD1 1 
ATOM   2358 C  CD2 . LEU B 2 36  ? -11.793 -13.771 29.08   1   47.67  ? 32  LEU A CD2 1 
ATOM   2359 N  N   . LYS B 2 37  ? -8.617  -14.074 25.213  1   49.35  ? 33  LYS A N   1 
ATOM   2360 C  CA  . LYS B 2 37  ? -7.536  -13.758 24.295  1   50.78  ? 33  LYS A CA  1 
ATOM   2361 C  C   . LYS B 2 37  ? -7.292  -12.247 24.284  1   53.01  ? 33  LYS A C   1 
ATOM   2362 O  O   . LYS B 2 37  ? -8.04   -11.51  23.671  1   54.47  ? 33  LYS A O   1 
ATOM   2363 C  CB  . LYS B 2 37  ? -7.957  -14.361 22.956  1   49.97  ? 33  LYS A CB  1 
ATOM   2364 C  CG  . LYS B 2 37  ? -6.976  -14.324 21.803  1   52.21  ? 33  LYS A CG  1 
ATOM   2365 C  CD  . LYS B 2 37  ? -7.534  -15.19  20.667  1   57.15  ? 33  LYS A CD  1 
ATOM   2366 C  CE  . LYS B 2 37  ? -6.586  -15.458 19.516  1   57.31  ? 33  LYS A CE  1 
ATOM   2367 N  NZ  . LYS B 2 37  ? -7.184  -16.235 18.432  1   54.03  ? 33  LYS A NZ  1 
ATOM   2368 N  N   . LYS B 2 38  ? -6.238  -11.787 24.957  1   57.39  ? 34  LYS A N   1 
ATOM   2369 C  CA  . LYS B 2 38  ? -5.894  -10.378 25.013  1   62.45  ? 34  LYS A CA  1 
ATOM   2370 C  C   . LYS B 2 38  ? -5.228  -9.924  23.716  1   68.71  ? 34  LYS A C   1 
ATOM   2371 O  O   . LYS B 2 38  ? -4.277  -10.56  23.259  1   70.89  ? 34  LYS A O   1 
ATOM   2372 C  CB  . LYS B 2 38  ? -4.966  -10.096 26.197  1   66.16  ? 34  LYS A CB  1 
ATOM   2373 C  CG  . LYS B 2 38  ? -4.609  -8.626  26.377  1   68.05  ? 34  LYS A CG  1 
ATOM   2374 C  CD  . LYS B 2 38  ? -3.726  -8.295  27.572  1   72.83  ? 34  LYS A CD  1 
ATOM   2375 C  CE  . LYS B 2 38  ? -3.322  -6.866  27.789  1   78.53  ? 34  LYS A CE  1 
ATOM   2376 N  NZ  . LYS B 2 38  ? -2.476  -6.732  28.98   1   81.44  ? 34  LYS A NZ  1 
ATOM   2377 N  N   . ILE B 2 39  ? -5.772  -8.835  23.164  1   71.84  ? 35  ILE A N   1 
ATOM   2378 C  CA  . ILE B 2 39  ? -5.187  -8.189  21.961  1   75.24  ? 35  ILE A CA  1 
ATOM   2379 C  C   . ILE B 2 39  ? -4.755  -6.81   22.467  1   79.89  ? 35  ILE A C   1 
ATOM   2380 O  O   . ILE B 2 39  ? -5.641  -6.005  22.813  1   81.87  ? 35  ILE A O   1 
ATOM   2381 C  CB  . ILE B 2 39  ? -6.212  -8.06   20.82   1   75.38  ? 35  ILE A CB  1 
ATOM   2382 C  CG1 . ILE B 2 39  ? -6.446  -9.381  20.104  1   74.15  ? 35  ILE A CG1 1 
ATOM   2383 C  CG2 . ILE B 2 39  ? -5.795  -6.973  19.829  1   71.57  ? 35  ILE A CG2 1 
ATOM   2384 C  CD1 . ILE B 2 39  ? -7.547  -10.237 20.693  1   73.74  ? 35  ILE A CD1 1 
ATOM   2385 N  N   . ARG B 2 40  ? -3.453  -6.579  22.587  1   85.18  ? 36  ARG A N   1 
ATOM   2386 C  CA  . ARG B 2 40  ? -3.002  -5.289  23.159  1   94.44  ? 36  ARG A CA  1 
ATOM   2387 C  C   . ARG B 2 40  ? -3.054  -4.236  22.047  1   99.78  ? 36  ARG A C   1 
ATOM   2388 O  O   . ARG B 2 40  ? -2.591  -4.528  20.926  1   96.91  ? 36  ARG A O   1 
ATOM   2389 C  CB  . ARG B 2 40  ? -1.613  -5.424  23.788  1   95.39  ? 36  ARG A CB  1 
ATOM   2390 C  CG  . ARG B 2 40  ? -1.453  -4.719  25.125  1   105.11 ? 36  ARG A CG  1 
ATOM   2391 C  CD  . ARG B 2 40  ? -2.665  -3.875  25.468  1   113.72 ? 36  ARG A CD  1 
ATOM   2392 N  NE  . ARG B 2 40  ? -2.448  -2.446  25.223  1   116.91 ? 36  ARG A NE  1 
ATOM   2393 C  CZ  . ARG B 2 40  ? -1.824  -1.639  26.066  1   112.64 ? 36  ARG A CZ  1 
ATOM   2394 N  NH1 . ARG B 2 40  ? -1.776  -1.941  27.35   1   106.87 ? 36  ARG A NH1 1 
ATOM   2395 N  NH2 . ARG B 2 40  ? -1.25   -0.535  25.622  1   107.11 ? 36  ARG A NH2 1 
ATOM   2396 N  N   . LEU B 2 41  ? -3.62   -3.071  22.353  1   100.17 ? 37  LEU A N   1 
ATOM   2397 C  CA  . LEU B 2 41  ? -3.751  -2      21.338  1   101.76 ? 37  LEU A CA  1 
ATOM   2398 C  C   . LEU B 2 41  ? -2.795  -0.851  21.694  1   108.47 ? 37  LEU A C   1 
ATOM   2399 O  O   . LEU B 2 41  ? -1.698  -0.816  21.095  1   112.43 ? 37  LEU A O   1 
ATOM   2400 C  CB  . LEU B 2 41  ? -5.21   -1.557  21.311  1   93.41  ? 37  LEU A CB  1 
ATOM   2401 C  CG  . LEU B 2 41  ? -6.239  -2.652  21.018  1   82.83  ? 37  LEU A CG  1 
ATOM   2402 C  CD1 . LEU B 2 41  ? -7.639  -2.15   21.314  1   81.9   ? 37  LEU A CD1 1 
ATOM   2403 C  CD2 . LEU B 2 41  ? -6.123  -3.065  19.569  1   76.66  ? 37  LEU A CD2 1 
ATOM   2404 N  N   . GLU B 2 46  ? -1.329  1.775   15.013  1   75.45  ? 42  GLU A N   1 
ATOM   2405 C  CA  . GLU B 2 46  ? -1.995  1.434   13.731  1   73.98  ? 42  GLU A CA  1 
ATOM   2406 C  C   . GLU B 2 46  ? -3.447  1.046   14.009  1   69.28  ? 42  GLU A C   1 
ATOM   2407 O  O   . GLU B 2 46  ? -4.16   0.688   13.06   1   67.91  ? 42  GLU A O   1 
ATOM   2408 C  CB  . GLU B 2 46  ? -1.239  0.31    13.032  1   77.49  ? 42  GLU A CB  1 
ATOM   2409 C  CG  . GLU B 2 46  ? -1.31   0.37    11.509  1   81.45  ? 42  GLU A CG  1 
ATOM   2410 C  CD  . GLU B 2 46  ? -0.721  1.605   10.854  1   90.94  ? 42  GLU A CD  1 
ATOM   2411 O  OE1 . GLU B 2 46  ? 0.165   2.262   11.434  1   91.36  ? 42  GLU A OE1 1 
ATOM   2412 O  OE2 . GLU B 2 46  ? -1.165  1.901   9.733   1   88.88  ? 42  GLU A OE2 1 
ATOM   2413 N  N   . GLY B 2 47  ? -3.859  1.098   15.268  1   67.96  ? 43  GLY A N   1 
ATOM   2414 C  CA  . GLY B 2 47  ? -5.266  0.834   15.598  1   63.99  ? 43  GLY A CA  1 
ATOM   2415 C  C   . GLY B 2 47  ? -5.555  -0.623  15.842  1   59.58  ? 43  GLY A C   1 
ATOM   2416 O  O   . GLY B 2 47  ? -4.626  -1.366  16.193  1   59.87  ? 43  GLY A O   1 
ATOM   2417 N  N   . VAL B 2 48  ? -6.817  -1.004  15.672  1   55.81  ? 44  VAL A N   1 
ATOM   2418 C  CA  . VAL B 2 48  ? -7.224  -2.416  15.897  1   52.72  ? 44  VAL A CA  1 
ATOM   2419 C  C   . VAL B 2 48  ? -6.649  -3.264  14.759  1   52.1   ? 44  VAL A C   1 
ATOM   2420 O  O   . VAL B 2 48  ? -6.846  -2.915  13.589  1   51.32  ? 44  VAL A O   1 
ATOM   2421 C  CB  . VAL B 2 48  ? -8.749  -2.57   16.035  1   50.43  ? 44  VAL A CB  1 
ATOM   2422 C  CG1 . VAL B 2 48  ? -9.156  -4.02   16.26   1   47.11  ? 44  VAL A CG1 1 
ATOM   2423 C  CG2 . VAL B 2 48  ? -9.297  -1.686  17.145  1   51.18  ? 44  VAL A CG2 1 
ATOM   2424 N  N   . PRO B 2 49  ? -5.921  -4.345  15.08   1   52.83  ? 45  PRO A N   1 
ATOM   2425 C  CA  . PRO B 2 49  ? -5.361  -5.208  14.056  1   51.59  ? 45  PRO A CA  1 
ATOM   2426 C  C   . PRO B 2 49  ? -6.378  -5.798  13.097  1   52.25  ? 45  PRO A C   1 
ATOM   2427 O  O   . PRO B 2 49  ? -7.495  -6.133  13.512  1   53.13  ? 45  PRO A O   1 
ATOM   2428 C  CB  . PRO B 2 49  ? -4.692  -6.271  14.93   1   49.26  ? 45  PRO A CB  1 
ATOM   2429 C  CG  . PRO B 2 49  ? -4.339  -5.545  16.194  1   52.13  ? 45  PRO A CG  1 
ATOM   2430 C  CD  . PRO B 2 49  ? -5.589  -4.739  16.433  1   53.55  ? 45  PRO A CD  1 
ATOM   2431 N  N   . SER B 2 50  ? -5.99   -5.93   11.832  1   52.28  ? 46  SER A N   1 
ATOM   2432 C  CA  . SER B 2 50  ? -6.872  -6.509  10.793  1   48.62  ? 46  SER A CA  1 
ATOM   2433 C  C   . SER B 2 50  ? -7.224  -7.938  11.187  1   48.04  ? 46  SER A C   1 
ATOM   2434 O  O   . SER B 2 50  ? -8.385  -8.324  11.022  1   50.47  ? 46  SER A O   1 
ATOM   2435 C  CB  . SER B 2 50  ? -6.168  -6.497  9.486   1   47.14  ? 46  SER A CB  1 
ATOM   2436 O  OG  . SER B 2 50  ? -4.972  -7.257  9.55    1   48.69  ? 46  SER A OG  1 
ATOM   2437 N  N   . THR B 2 51  ? -6.24   -8.672  11.69   1   50     ? 47  THR A N   1 
ATOM   2438 C  CA  . THR B 2 51  ? -6.445  -10.065 12.108  1   48.23  ? 47  THR A CA  1 
ATOM   2439 C  C   . THR B 2 51  ? -7.6    -10.133 13.071  1   45.01  ? 47  THR A C   1 
ATOM   2440 O  O   . THR B 2 51  ? -8.445  -11.023 12.913  1   41.82  ? 47  THR A O   1 
ATOM   2441 C  CB  . THR B 2 51  ? -5.133  -10.544 12.727  1   45.96  ? 47  THR A CB  1 
ATOM   2442 O  OG1 . THR B 2 51  ? -4.645  -9.446  13.487  1   50.59  ? 47  THR A OG1 1 
ATOM   2443 C  CG2 . THR B 2 51  ? -4.105  -10.921 11.677  1   48.23  ? 47  THR A CG2 1 
ATOM   2444 N  N   . ALA B 2 52  ? -7.644  -9.216  14.03   1   44.95  ? 48  ALA A N   1 
ATOM   2445 C  CA  . ALA B 2 52  ? -8.696  -9.22   15.064  1   47.17  ? 48  ALA A CA  1 
ATOM   2446 C  C   . ALA B 2 52  ? -10.032 -8.817  14.452  1   51.3   ? 48  ALA A C   1 
ATOM   2447 O  O   . ALA B 2 52  ? -11.042 -9.467  14.739  1   51.62  ? 48  ALA A O   1 
ATOM   2448 C  CB  . ALA B 2 52  ? -8.284  -8.278  16.156  1   45     ? 48  ALA A CB  1 
ATOM   2449 N  N   . ILE B 2 53  ? -10.024 -7.778  13.626  1   49.82  ? 49  ILE A N   1 
ATOM   2450 C  CA  . ILE B 2 53  ? -11.268 -7.313  12.953  1   49.12  ? 49  ILE A CA  1 
ATOM   2451 C  C   . ILE B 2 53  ? -11.867 -8.502  12.19   1   45.88  ? 49  ILE A C   1 
ATOM   2452 O  O   . ILE B 2 53  ? -13.082 -8.734  12.308  1   43.97  ? 49  ILE A O   1 
ATOM   2453 C  CB  . ILE B 2 53  ? -10.948 -6.107  12.051  1   50.86  ? 49  ILE A CB  1 
ATOM   2454 C  CG1 . ILE B 2 53  ? -10.949 -4.806  12.84   1   52.33  ? 49  ILE A CG1 1 
ATOM   2455 C  CG2 . ILE B 2 53  ? -11.888 -6.038  10.847  1   50.93  ? 49  ILE A CG2 1 
ATOM   2456 C  CD1 . ILE B 2 53  ? -9.909  -3.809  12.369  1   53.87  ? 49  ILE A CD1 1 
ATOM   2457 N  N   . ARG B 2 54  ? -11.024 -9.26   11.5    1   43.86  ? 50  ARG A N   1 
ATOM   2458 C  CA  . ARG B 2 54  ? -11.499 -10.428 10.724  1   41.78  ? 50  ARG A CA  1 
ATOM   2459 C  C   . ARG B 2 54  ? -11.947 -11.535 11.686  1   41.54  ? 50  ARG A C   1 
ATOM   2460 O  O   . ARG B 2 54  ? -13.016 -12.097 11.458  1   43.86  ? 50  ARG A O   1 
ATOM   2461 C  CB  . ARG B 2 54  ? -10.401 -10.857 9.745   1   39.49  ? 50  ARG A CB  1 
ATOM   2462 C  CG  . ARG B 2 54  ? -10.352 -10.062 8.45    1   39.28  ? 50  ARG A CG  1 
ATOM   2463 C  CD  . ARG B 2 54  ? -8.991  -10.16  7.789   1   38.98  ? 50  ARG A CD  1 
ATOM   2464 N  NE  . ARG B 2 54  ? -9.054  -9.832  6.361   1   40.94  ? 50  ARG A NE  1 
ATOM   2465 C  CZ  . ARG B 2 54  ? -8.036  -9.924  5.522   1   41.19  ? 50  ARG A CZ  1 
ATOM   2466 N  NH1 . ARG B 2 54  ? -7.14   -10.877 5.678   1   39.64  ? 50  ARG A NH1 1 
ATOM   2467 N  NH2 . ARG B 2 54  ? -7.919  -9.064  4.53    1   40.43  ? 50  ARG A NH2 1 
ATOM   2468 N  N   . GLU B 2 55  ? -11.18  -11.814 12.732  1   41.61  ? 51  GLU A N   1 
ATOM   2469 C  CA  . GLU B 2 55  ? -11.546 -12.943 13.623  1   42.82  ? 51  GLU A CA  1 
ATOM   2470 C  C   . GLU B 2 55  ? -12.913 -12.659 14.262  1   40.72  ? 51  GLU A C   1 
ATOM   2471 O  O   . GLU B 2 55  ? -13.793 -13.515 14.158  1   38.46  ? 51  GLU A O   1 
ATOM   2472 C  CB  . GLU B 2 55  ? -10.462 -13.229 14.665  1   45.21  ? 51  GLU A CB  1 
ATOM   2473 C  CG  . GLU B 2 55  ? -10.816 -14.379 15.601  1   46.84  ? 51  GLU A CG  1 
ATOM   2474 C  CD  . GLU B 2 55  ? -9.634  -14.998 16.316  1   52.21  ? 51  GLU A CD  1 
ATOM   2475 O  OE1 . GLU B 2 55  ? -8.699  -14.254 16.661  1   47.96  ? 51  GLU A OE1 1 
ATOM   2476 O  OE2 . GLU B 2 55  ? -9.652  -16.225 16.53   1   58.32  ? 51  GLU A OE2 1 
ATOM   2477 N  N   . ILE B 2 56  ? -13.082 -11.489 14.865  1   39.87  ? 52  ILE A N   1 
ATOM   2478 C  CA  . ILE B 2 56  ? -14.35  -11.183 15.582  1   41.15  ? 52  ILE A CA  1 
ATOM   2479 C  C   . ILE B 2 56  ? -15.512 -11.187 14.58   1   44.48  ? 52  ILE A C   1 
ATOM   2480 O  O   . ILE B 2 56  ? -16.458 -11.953 14.801  1   47.63  ? 52  ILE A O   1 
ATOM   2481 C  CB  . ILE B 2 56  ? -14.237 -9.856  16.352  1   42.99  ? 52  ILE A CB  1 
ATOM   2482 C  CG1 . ILE B 2 56  ? -13.105 -9.901  17.366  1   42.03  ? 52  ILE A CG1 1 
ATOM   2483 C  CG2 . ILE B 2 56  ? -15.566 -9.492  17.008  1   43.14  ? 52  ILE A CG2 1 
ATOM   2484 C  CD1 . ILE B 2 56  ? -12.548 -8.542  17.738  1   42.15  ? 52  ILE A CD1 1 
ATOM   2485 N  N   . SER B 2 57  ? -15.428 -10.391 13.521  1   43.84  ? 53  SER A N   1 
ATOM   2486 C  CA  . SER B 2 57  ? -16.539 -10.286 12.544  1   43.62  ? 53  SER A CA  1 
ATOM   2487 C  C   . SER B 2 57  ? -16.953 -11.67  12.044  1   44.42  ? 53  SER A C   1 
ATOM   2488 O  O   . SER B 2 57  ? -18.161 -11.963 12.039  1   45.98  ? 53  SER A O   1 
ATOM   2489 C  CB  . SER B 2 57  ? -16.167 -9.39   11.392  1   44.12  ? 53  SER A CB  1 
ATOM   2490 O  OG  . SER B 2 57  ? -14.944 -9.786  10.791  1   47.45  ? 53  SER A OG  1 
ATOM   2491 N  N   . LEU B 2 58  ? -15.986 -12.499 11.67   1   42.2   ? 54  LEU A N   1 
ATOM   2492 C  CA  . LEU B 2 58  ? -16.338 -13.796 11.049  1   41.41  ? 54  LEU A CA  1 
ATOM   2493 C  C   . LEU B 2 58  ? -16.825 -14.784 12.116  1   44.75  ? 54  LEU A C   1 
ATOM   2494 O  O   . LEU B 2 58  ? -17.777 -15.512 11.83   1   47.84  ? 54  LEU A O   1 
ATOM   2495 C  CB  . LEU B 2 58  ? -15.153 -14.301 10.23   1   36.97  ? 54  LEU A CB  1 
ATOM   2496 C  CG  . LEU B 2 58  ? -14.68  -13.377 9.105   1   37.12  ? 54  LEU A CG  1 
ATOM   2497 C  CD1 . LEU B 2 58  ? -13.514 -13.964 8.335   1   35.67  ? 54  LEU A CD1 1 
ATOM   2498 C  CD2 . LEU B 2 58  ? -15.805 -12.985 8.172   1   34.97  ? 54  LEU A CD2 1 
ATOM   2499 N  N   . LEU B 2 59  ? -16.234 -14.767 13.306  1   45.67  ? 55  LEU A N   1 
ATOM   2500 C  CA  . LEU B 2 59  ? -16.619 -15.736 14.364  1   45.4   ? 55  LEU A CA  1 
ATOM   2501 C  C   . LEU B 2 59  ? -17.94  -15.292 15.005  1   48.91  ? 55  LEU A C   1 
ATOM   2502 O  O   . LEU B 2 59  ? -18.569 -16.111 15.693  1   49.2   ? 55  LEU A O   1 
ATOM   2503 C  CB  . LEU B 2 59  ? -15.51  -15.887 15.399  1   42.56  ? 55  LEU A CB  1 
ATOM   2504 C  CG  . LEU B 2 59  ? -14.435 -16.924 15.075  1   42.21  ? 55  LEU A CG  1 
ATOM   2505 C  CD1 . LEU B 2 59  ? -13.459 -17.023 16.226  1   41.53  ? 55  LEU A CD1 1 
ATOM   2506 C  CD2 . LEU B 2 59  ? -15.085 -18.263 14.802  1   40.28  ? 55  LEU A CD2 1 
ATOM   2507 N  N   . LYS B 2 60  ? -18.341 -14.047 14.774  1   51.09  ? 56  LYS A N   1 
ATOM   2508 C  CA  . LYS B 2 60  ? -19.623 -13.539 15.306  1   53.8   ? 56  LYS A CA  1 
ATOM   2509 C  C   . LYS B 2 60  ? -20.769 -14.174 14.529  1   56.46  ? 56  LYS A C   1 
ATOM   2510 O  O   . LYS B 2 60  ? -21.876 -14.266 15.079  1   62.1   ? 56  LYS A O   1 
ATOM   2511 C  CB  . LYS B 2 60  ? -19.72  -12.038 15.062  1   53.61  ? 56  LYS A CB  1 
ATOM   2512 C  CG  . LYS B 2 60  ? -19.327 -11.135 16.201  1   53.75  ? 56  LYS A CG  1 
ATOM   2513 C  CD  . LYS B 2 60  ? -20.089 -9.827  16.056  1   61.04  ? 56  LYS A CD  1 
ATOM   2514 C  CE  . LYS B 2 60  ? -21.437 -9.916  16.691  1   63.71  ? 56  LYS A CE  1 
ATOM   2515 N  NZ  . LYS B 2 60  ? -21.87  -8.611  17.191  1   68.71  ? 56  LYS A NZ  1 
ATOM   2516 N  N   . GLU B 2 61  ? -20.502 -14.594 13.3    1   52.39  ? 57  GLU A N   1 
ATOM   2517 C  CA  . GLU B 2 61  ? -21.589 -15.131 12.452  1   54.61  ? 57  GLU A CA  1 
ATOM   2518 C  C   . GLU B 2 61  ? -21.397 -16.635 12.209  1   51.08  ? 57  GLU A C   1 
ATOM   2519 O  O   . GLU B 2 61  ? -22.294 -17.259 11.619  1   52.16  ? 57  GLU A O   1 
ATOM   2520 C  CB  . GLU B 2 61  ? -21.652 -14.261 11.197  1   63.97  ? 57  GLU A CB  1 
ATOM   2521 C  CG  . GLU B 2 61  ? -20.362 -14.119 10.4    1   70.74  ? 57  GLU A CG  1 
ATOM   2522 C  CD  . GLU B 2 61  ? -20.642 -13.156 9.261   1   76.34  ? 57  GLU A CD  1 
ATOM   2523 O  OE1 . GLU B 2 61  ? -20.575 -11.934 9.493   1   75.02  ? 57  GLU A OE1 1 
ATOM   2524 O  OE2 . GLU B 2 61  ? -20.962 -13.623 8.151   1   69.82  ? 57  GLU A OE2 1 
ATOM   2525 N  N   . LEU B 2 62  ? -20.289 -17.191 12.677  1   46.32  ? 58  LEU A N   1 
ATOM   2526 C  CA  . LEU B 2 62  ? -20.006 -18.63  12.468  1   45.37  ? 58  LEU A CA  1 
ATOM   2527 C  C   . LEU B 2 62  ? -20.403 -19.396 13.735  1   45.14  ? 58  LEU A C   1 
ATOM   2528 O  O   . LEU B 2 62  ? -19.52  -19.78  14.506  1   47.7   ? 58  LEU A O   1 
ATOM   2529 C  CB  . LEU B 2 62  ? -18.546 -18.838 12.08   1   41.63  ? 58  LEU A CB  1 
ATOM   2530 C  CG  . LEU B 2 62  ? -18.163 -18.425 10.657  1   43.32  ? 58  LEU A CG  1 
ATOM   2531 C  CD1 . LEU B 2 62  ? -16.661 -18.489 10.486  1   39.93  ? 58  LEU A CD1 1 
ATOM   2532 C  CD2 . LEU B 2 62  ? -18.857 -19.269 9.61    1   40.73  ? 58  LEU A CD2 1 
ATOM   2533 N  N   . ASN B 2 63  ? -21.699 -19.599 13.924  1   46.51  ? 59  ASN A N   1 
ATOM   2534 C  CA  . ASN B 2 63  ? -22.203 -20.332 15.109  1   49.46  ? 59  ASN A CA  1 
ATOM   2535 C  C   . ASN B 2 63  ? -22.426 -21.791 14.711  1   46.66  ? 59  ASN A C   1 
ATOM   2536 O  O   . ASN B 2 63  ? -23.422 -22.073 14.036  1   50.37  ? 59  ASN A O   1 
ATOM   2537 C  CB  . ASN B 2 63  ? -23.45  -19.661 15.672  1   57.05  ? 59  ASN A CB  1 
ATOM   2538 C  CG  . ASN B 2 63  ? -23.136 -18.453 16.52   1   79.45  ? 59  ASN A CG  1 
ATOM   2539 O  OD1 . ASN B 2 63  ? -23.815 -18.213 17.523  1   99.25  ? 59  ASN A OD1 1 
ATOM   2540 N  ND2 . ASN B 2 63  ? -22.131 -17.676 16.143  1   73.97  ? 59  ASN A ND2 1 
ATOM   2541 N  N   . HIS B 2 64  ? -21.516 -22.672 15.115  1   40.85  ? 60  HIS A N   1 
ATOM   2542 C  CA  . HIS B 2 64  ? -21.603 -24.106 14.751  1   38.33  ? 60  HIS A CA  1 
ATOM   2543 C  C   . HIS B 2 64  ? -20.891 -24.913 15.835  1   40.66  ? 60  HIS A C   1 
ATOM   2544 O  O   . HIS B 2 64  ? -19.884 -24.462 16.39   1   41.28  ? 60  HIS A O   1 
ATOM   2545 C  CB  . HIS B 2 64  ? -21.054 -24.33  13.338  1   36.25  ? 60  HIS A CB  1 
ATOM   2546 C  CG  . HIS B 2 64  ? -21.164 -25.725 12.825  1   37.47  ? 60  HIS A CG  1 
ATOM   2547 N  ND1 . HIS B 2 64  ? -20.238 -26.701 13.108  1   34.98  ? 60  HIS A ND1 1 
ATOM   2548 C  CD2 . HIS B 2 64  ? -22.082 -26.304 12.053  1   34.39  ? 60  HIS A CD2 1 
ATOM   2549 C  CE1 . HIS B 2 64  ? -20.602 -27.829 12.526  1   33.92  ? 60  HIS A CE1 1 
ATOM   2550 N  NE2 . HIS B 2 64  ? -21.717 -27.609 11.876  1   33.36  ? 60  HIS A NE2 1 
ATOM   2551 N  N   . PRO B 2 65  ? -21.416 -26.101 16.184  1   42.55  ? 61  PRO A N   1 
ATOM   2552 C  CA  . PRO B 2 65  ? -20.808 -26.94  17.206  1   40.71  ? 61  PRO A CA  1 
ATOM   2553 C  C   . PRO B 2 65  ? -19.356 -27.314 17.016  1   38.29  ? 61  PRO A C   1 
ATOM   2554 O  O   . PRO B 2 65  ? -18.71  -27.697 17.987  1   40.32  ? 61  PRO A O   1 
ATOM   2555 C  CB  . PRO B 2 65  ? -21.705 -28.168 17.035  1   39.07  ? 61  PRO A CB  1 
ATOM   2556 C  CG  . PRO B 2 65  ? -23.049 -27.606 16.713  1   38.99  ? 61  PRO A CG  1 
ATOM   2557 C  CD  . PRO B 2 65  ? -22.656 -26.627 15.647  1   38.65  ? 61  PRO A CD  1 
ATOM   2558 N  N   . ASN B 2 66  ? -18.859 -27.23  15.789  1   36.06  ? 62  ASN A N   1 
ATOM   2559 C  CA  . ASN B 2 66  ? -17.481 -27.684 15.484  1   36.4   ? 62  ASN A CA  1 
ATOM   2560 C  C   . ASN B 2 66  ? -16.646 -26.447 15.163  1   37.87  ? 62  ASN A C   1 
ATOM   2561 O  O   . ASN B 2 66  ? -15.598 -26.585 14.523  1   36.74  ? 62  ASN A O   1 
ATOM   2562 C  CB  . ASN B 2 66  ? -17.535 -28.796 14.448  1   34.89  ? 62  ASN A CB  1 
ATOM   2563 C  CG  . ASN B 2 66  ? -18.281 -29.998 14.967  1   39.66  ? 62  ASN A CG  1 
ATOM   2564 O  OD1 . ASN B 2 66  ? -19.247 -30.448 14.347  1   44.07  ? 62  ASN A OD1 1 
ATOM   2565 N  ND2 . ASN B 2 66  ? -17.854 -30.52  16.106  1   39.15  ? 62  ASN A ND2 1 
ATOM   2566 N  N   . ILE B 2 67  ? -17.132 -25.282 15.579  1   37.09  ? 63  ILE A N   1 
ATOM   2567 C  CA  . ILE B 2 67  ? -16.346 -24.03  15.439  1   36.9   ? 63  ILE A CA  1 
ATOM   2568 C  C   . ILE B 2 67  ? -16.261 -23.41  16.841  1   39.64  ? 63  ILE A C   1 
ATOM   2569 O  O   . ILE B 2 67  ? -17.266 -23.459 17.559  1   39.78  ? 63  ILE A O   1 
ATOM   2570 C  CB  . ILE B 2 67  ? -16.974 -23.074 14.411  1   37.37  ? 63  ILE A CB  1 
ATOM   2571 C  CG1 . ILE B 2 67  ? -17.189 -23.751 13.061  1   39.56  ? 63  ILE A CG1 1 
ATOM   2572 C  CG2 . ILE B 2 67  ? -16.151 -21.796 14.271  1   36.88  ? 63  ILE A CG2 1 
ATOM   2573 C  CD1 . ILE B 2 67  ? -17.848 -22.862 12.024  1   38.31  ? 63  ILE A CD1 1 
ATOM   2574 N  N   . VAL B 2 68  ? -15.096 -22.878 17.213  1   39.83  ? 64  VAL A N   1 
ATOM   2575 C  CA  . VAL B 2 68  ? -14.913 -22.194 18.527  1   38.58  ? 64  VAL A CA  1 
ATOM   2576 C  C   . VAL B 2 68  ? -15.973 -21.099 18.677  1   37.63  ? 64  VAL A C   1 
ATOM   2577 O  O   . VAL B 2 68  ? -16.338 -20.473 17.676  1   38.64  ? 64  VAL A O   1 
ATOM   2578 C  CB  . VAL B 2 68  ? -13.49  -21.629 18.703  1   39.51  ? 64  VAL A CB  1 
ATOM   2579 C  CG1 . VAL B 2 68  ? -13.211 -20.421 17.821  1   33.86  ? 64  VAL A CG1 1 
ATOM   2580 C  CG2 . VAL B 2 68  ? -13.156 -21.348 20.161  1   41.98  ? 64  VAL A CG2 1 
ATOM   2581 N  N   . LYS B 2 69  ? -16.422 -20.875 19.905  1   40.22  ? 65  LYS A N   1 
ATOM   2582 C  CA  . LYS B 2 69  ? -17.51  -19.904 20.138  1   40.36  ? 65  LYS A CA  1 
ATOM   2583 C  C   . LYS B 2 69  ? -16.993 -18.616 20.774  1   41.11  ? 65  LYS A C   1 
ATOM   2584 O  O   . LYS B 2 69  ? -16.505 -18.675 21.905  1   43.58  ? 65  LYS A O   1 
ATOM   2585 C  CB  . LYS B 2 69  ? -18.576 -20.558 21.017  1   43.12  ? 65  LYS A CB  1 
ATOM   2586 C  CG  . LYS B 2 69  ? -19.85  -19.755 21.194  1   53.14  ? 65  LYS A CG  1 
ATOM   2587 C  CD  . LYS B 2 69  ? -20.395 -19.201 19.885  1   63.68  ? 65  LYS A CD  1 
ATOM   2588 C  CE  . LYS B 2 69  ? -21.726 -18.563 20.084  1   75.93  ? 65  LYS A CE  1 
ATOM   2589 N  NZ  . LYS B 2 69  ? -22.52  -19.33  21.046  1   75.09  ? 65  LYS A NZ  1 
ATOM   2590 N  N   . LEU B 2 70  ? -17.088 -17.509 20.046  1   39.12  ? 66  LEU A N   1 
ATOM   2591 C  CA  . LEU B 2 70  ? -16.768 -16.193 20.635  1   39.09  ? 66  LEU A CA  1 
ATOM   2592 C  C   . LEU B 2 70  ? -17.99  -15.819 21.468  1   39.63  ? 66  LEU A C   1 
ATOM   2593 O  O   . LEU B 2 70  ? -19.084 -15.745 20.897  1   41.11  ? 66  LEU A O   1 
ATOM   2594 C  CB  . LEU B 2 70  ? -16.504 -15.165 19.543  1   39.19  ? 66  LEU A CB  1 
ATOM   2595 C  CG  . LEU B 2 70  ? -15.915 -13.828 19.996  1   40.87  ? 66  LEU A CG  1 
ATOM   2596 C  CD1 . LEU B 2 70  ? -14.644 -14.068 20.782  1   44.17  ? 66  LEU A CD1 1 
ATOM   2597 C  CD2 . LEU B 2 70  ? -15.634 -12.989 18.768  1   39.3   ? 66  LEU A CD2 1 
ATOM   2598 N  N   . LEU B 2 71  ? -17.804 -15.634 22.768  1   40.24  ? 67  LEU A N   1 
ATOM   2599 C  CA  . LEU B 2 71  ? -18.949 -15.366 23.665  1   42.08  ? 67  LEU A CA  1 
ATOM   2600 C  C   . LEU B 2 71  ? -19.121 -13.857 23.829  1   43.98  ? 67  LEU A C   1 
ATOM   2601 O  O   . LEU B 2 71  ? -20.269 -13.407 23.943  1   45.24  ? 67  LEU A O   1 
ATOM   2602 C  CB  . LEU B 2 71  ? -18.657 -16.056 24.992  1   44     ? 67  LEU A CB  1 
ATOM   2603 C  CG  . LEU B 2 71  ? -18.413 -17.565 24.937  1   46.64  ? 67  LEU A CG  1 
ATOM   2604 C  CD1 . LEU B 2 71  ? -17.866 -18.012 26.274  1   46.11  ? 67  LEU A CD1 1 
ATOM   2605 C  CD2 . LEU B 2 71  ? -19.714 -18.276 24.64   1   45.03  ? 67  LEU A CD2 1 
ATOM   2606 N  N   . ASP B 2 72  ? -18.012 -13.124 23.81   1   44.44  ? 68  ASP A N   1 
ATOM   2607 C  CA  . ASP B 2 72  ? -18.076 -11.661 24.015  1   47.75  ? 68  ASP A CA  1 
ATOM   2608 C  C   . ASP B 2 72  ? -16.787 -10.989 23.564  1   48.13  ? 68  ASP A C   1 
ATOM   2609 O  O   . ASP B 2 72  ? -15.786 -11.69  23.367  1   48.33  ? 68  ASP A O   1 
ATOM   2610 C  CB  . ASP B 2 72  ? -18.356 -11.301 25.466  1   50.58  ? 68  ASP A CB  1 
ATOM   2611 C  CG  . ASP B 2 72  ? -19.016 -9.952  25.691  1   56.32  ? 68  ASP A CG  1 
ATOM   2612 O  OD1 . ASP B 2 72  ? -19.258 -9.249  24.695  1   56.4   ? 68  ASP A OD1 1 
ATOM   2613 O  OD2 . ASP B 2 72  ? -19.275 -9.622  26.858  1   60.38  ? 68  ASP A OD2 1 
ATOM   2614 N  N   . VAL B 2 73  ? -16.85  -9.675  23.378  1   47.66  ? 69  VAL A N   1 
ATOM   2615 C  CA  . VAL B 2 73  ? -15.643 -8.877  23.043  1   49.32  ? 69  VAL A CA  1 
ATOM   2616 C  C   . VAL B 2 73  ? -15.656 -7.713  24.038  1   53.6   ? 69  VAL A C   1 
ATOM   2617 O  O   . VAL B 2 73  ? -16.646 -6.966  24.058  1   54.96  ? 69  VAL A O   1 
ATOM   2618 C  CB  . VAL B 2 73  ? -15.603 -8.386  21.587  1   49     ? 69  VAL A CB  1 
ATOM   2619 C  CG1 . VAL B 2 73  ? -14.494 -7.369  21.36   1   48.52  ? 69  VAL A CG1 1 
ATOM   2620 C  CG2 . VAL B 2 73  ? -15.481 -9.543  20.608  1   46.25  ? 69  VAL A CG2 1 
ATOM   2621 N  N   . ILE B 2 74  ? -14.627 -7.61   24.871  1   56.34  ? 70  ILE A N   1 
ATOM   2622 C  CA  . ILE B 2 74  ? -14.609 -6.545  25.914  1   62.66  ? 70  ILE A CA  1 
ATOM   2623 C  C   . ILE B 2 74  ? -13.545 -5.501  25.56   1   65.41  ? 70  ILE A C   1 
ATOM   2624 O  O   . ILE B 2 74  ? -12.38  -5.882  25.377  1   62.8   ? 70  ILE A O   1 
ATOM   2625 C  CB  . ILE B 2 74  ? -14.41  -7.135  27.321  1   64.29  ? 70  ILE A CB  1 
ATOM   2626 C  CG1 . ILE B 2 74  ? -15.689 -7.792  27.827  1   64.61  ? 70  ILE A CG1 1 
ATOM   2627 C  CG2 . ILE B 2 74  ? -13.903 -6.075  28.297  1   65.45  ? 70  ILE A CG2 1 
ATOM   2628 C  CD1 . ILE B 2 74  ? -15.473 -9.11   28.544  1   62.36  ? 70  ILE A CD1 1 
ATOM   2629 N  N   . HIS B 2 75  ? -13.965 -4.245  25.435  1   77.58  ? 71  HIS A N   1 
ATOM   2630 C  CA  . HIS B 2 75  ? -13.022 -3.133  25.166  1   92.41  ? 71  HIS A CA  1 
ATOM   2631 C  C   . HIS B 2 75  ? -12.796 -2.377  26.471  1   98.76  ? 71  HIS A C   1 
ATOM   2632 O  O   . HIS B 2 75  ? -13.556 -1.436  26.759  1   98.31  ? 71  HIS A O   1 
ATOM   2633 C  CB  . HIS B 2 75  ? -13.593 -2.101  24.192  1   97.45  ? 71  HIS A CB  1 
ATOM   2634 C  CG  . HIS B 2 75  ? -14.442 -2.589  23.068  1   111.16 ? 71  HIS A CG  1 
ATOM   2635 N  ND1 . HIS B 2 75  ? -14.285 -2.058  21.807  1   125.59 ? 71  HIS A ND1 1 
ATOM   2636 C  CD2 . HIS B 2 75  ? -15.445 -3.47   22.973  1   106.92 ? 71  HIS A CD2 1 
ATOM   2637 C  CE1 . HIS B 2 75  ? -15.155 -2.62   20.984  1   115.81 ? 71  HIS A CE1 1 
ATOM   2638 N  NE2 . HIS B 2 75  ? -15.866 -3.484  21.67   1   110.09 ? 71  HIS A NE2 1 
ATOM   2639 N  N   . THR B 2 76  ? -11.789 -2.776  27.244  1   108.87 ? 72  THR A N   1 
ATOM   2640 C  CA  . THR B 2 76  ? -11.468 -2.051  28.485  1   113.04 ? 72  THR A CA  1 
ATOM   2641 C  C   . THR B 2 76  ? -10.498 -0.945  28.14   1   122.91 ? 72  THR A C   1 
ATOM   2642 O  O   . THR B 2 76  ? -10.674 -0.326  27.068  1   122.17 ? 72  THR A O   1 
ATOM   2643 C  CB  . THR B 2 76  ? -10.941 -3.036  29.527  1   115.49 ? 72  THR A CB  1 
ATOM   2644 O  OG1 . THR B 2 76  ? -10.445 -2.277  30.625  1   132.32 ? 72  THR A OG1 1 
ATOM   2645 C  CG2 . THR B 2 76  ? -9.845  -3.928  28.978  1   113.76 ? 72  THR A CG2 1 
ATOM   2646 N  N   . GLU B 2 77  ? -9.51   -0.681  28.995  1   135.77 ? 73  GLU A N   1 
ATOM   2647 C  CA  . GLU B 2 77  ? -8.602  0.47    28.757  1   140.35 ? 73  GLU A CA  1 
ATOM   2648 C  C   . GLU B 2 77  ? -7.447  0.052   27.836  1   129.02 ? 73  GLU A C   1 
ATOM   2649 O  O   . GLU B 2 77  ? -6.622  -0.77   28.269  1   135.42 ? 73  GLU A O   1 
ATOM   2650 C  CB  . GLU B 2 77  ? -8.11   1.004   30.1    1   150.96 ? 73  GLU A CB  1 
ATOM   2651 C  CG  . GLU B 2 77  ? -9.207  1.091   31.158  1   159    ? 73  GLU A CG  1 
ATOM   2652 C  CD  . GLU B 2 77  ? -8.697  1.487   32.533  1   165.72 ? 73  GLU A CD  1 
ATOM   2653 O  OE1 . GLU B 2 77  ? -7.844  2.397   32.608  1   156.87 ? 73  GLU A OE1 1 
ATOM   2654 O  OE2 . GLU B 2 77  ? -9.149  0.886   33.53   1   182.13 ? 73  GLU A OE2 1 
ATOM   2655 N  N   . ASN B 2 78  ? -7.393  0.614   26.626  1   111.13 ? 74  ASN A N   1 
ATOM   2656 C  CA  . ASN B 2 78  ? -6.305  0.298   25.661  1   101.33 ? 74  ASN A CA  1 
ATOM   2657 C  C   . ASN B 2 78  ? -6.177  -1.216  25.505  1   90.18  ? 74  ASN A C   1 
ATOM   2658 O  O   . ASN B 2 78  ? -5.054  -1.682  25.267  1   94.54  ? 74  ASN A O   1 
ATOM   2659 C  CB  . ASN B 2 78  ? -4.985  0.93    26.082  1   107.04 ? 74  ASN A CB  1 
ATOM   2660 C  CG  . ASN B 2 78  ? -4.989  2.431   25.915  1   110.06 ? 74  ASN A CG  1 
ATOM   2661 O  OD1 . ASN B 2 78  ? -5.768  2.967   25.119  1   111.98 ? 74  ASN A OD1 1 
ATOM   2662 N  ND2 . ASN B 2 78  ? -4.138  3.124   26.656  1   106.12 ? 74  ASN A ND2 1 
ATOM   2663 N  N   . LYS B 2 79  ? -7.286  -1.945  25.604  1   81.67  ? 75  LYS A N   1 
ATOM   2664 C  CA  . LYS B 2 79  ? -7.211  -3.422  25.549  1   79.18  ? 75  LYS A CA  1 
ATOM   2665 C  C   . LYS B 2 79  ? -8.49   -4.02   24.954  1   75.84  ? 75  LYS A C   1 
ATOM   2666 O  O   . LYS B 2 79  ? -9.578  -3.512  25.268  1   81.05  ? 75  LYS A O   1 
ATOM   2667 C  CB  . LYS B 2 79  ? -7.035  -3.961  26.967  1   79.56  ? 75  LYS A CB  1 
ATOM   2668 C  CG  . LYS B 2 79  ? -5.725  -3.629  27.638  1   83.64  ? 75  LYS A CG  1 
ATOM   2669 C  CD  . LYS B 2 79  ? -5.63   -4.177  29.055  1   89.19  ? 75  LYS A CD  1 
ATOM   2670 C  CE  . LYS B 2 79  ? -4.32   -3.861  29.696  1   94.33  ? 75  LYS A CE  1 
ATOM   2671 N  NZ  . LYS B 2 79  ? -4.264  -4.377  31.066  1   94.42  ? 75  LYS A NZ  1 
ATOM   2672 N  N   . LEU B 2 80  ? -8.351  -5.057  24.13   1   68.34  ? 76  LEU A N   1 
ATOM   2673 C  CA  . LEU B 2 80  ? -9.532  -5.768  23.59   1   63.96  ? 76  LEU A CA  1 
ATOM   2674 C  C   . LEU B 2 80  ? -9.435  -7.229  24.046  1   63.75  ? 76  LEU A C   1 
ATOM   2675 O  O   . LEU B 2 80  ? -8.375  -7.844  23.845  1   63.66  ? 76  LEU A O   1 
ATOM   2676 C  CB  . LEU B 2 80  ? -9.592  -5.646  22.073  1   64.25  ? 76  LEU A CB  1 
ATOM   2677 C  CG  . LEU B 2 80  ? -10.966 -5.842  21.433  1   60.5   ? 76  LEU A CG  1 
ATOM   2678 C  CD1 . LEU B 2 80  ? -11.823 -4.631  21.725  1   64.51  ? 76  LEU A CD1 1 
ATOM   2679 C  CD2 . LEU B 2 80  ? -10.778 -6.011  19.942  1   56.42  ? 76  LEU A CD2 1 
ATOM   2680 N  N   . TYR B 2 81  ? -10.495 -7.741  24.665  1   64.55  ? 77  TYR A N   1 
ATOM   2681 C  CA  . TYR B 2 81  ? -10.481 -9.125  25.2    1   59.12  ? 77  TYR A CA  1 
ATOM   2682 C  C   . TYR B 2 81  ? -11.497 -9.962  24.458  1   53.28  ? 77  TYR A C   1 
ATOM   2683 O  O   . TYR B 2 81  ? -12.682 -9.608  24.399  1   53.62  ? 77  TYR A O   1 
ATOM   2684 C  CB  . TYR B 2 81  ? -10.797 -9.101  26.695  1   60.37  ? 77  TYR A CB  1 
ATOM   2685 C  CG  . TYR B 2 81  ? -9.637  -8.731  27.607  1   65.02  ? 77  TYR A CG  1 
ATOM   2686 C  CD1 . TYR B 2 81  ? -8.71   -9.682  28.008  1   65.58  ? 77  TYR A CD1 1 
ATOM   2687 C  CD2 . TYR B 2 81  ? -9.482  -7.433  28.073  1   67.91  ? 77  TYR A CD2 1 
ATOM   2688 C  CE1 . TYR B 2 81  ? -7.658  -9.351  28.845  1   68.48  ? 77  TYR A CE1 1 
ATOM   2689 C  CE2 . TYR B 2 81  ? -8.433  -7.089  28.908  1   69.96  ? 77  TYR A CE2 1 
ATOM   2690 C  CZ  . TYR B 2 81  ? -7.519  -8.051  29.294  1   71.23  ? 77  TYR A CZ  1 
ATOM   2691 O  OH  . TYR B 2 81  ? -6.484  -7.715  30.116  1   77.47  ? 77  TYR A OH  1 
ATOM   2692 N  N   . LEU B 2 82  ? -11.027 -11.061 23.89   1   49.47  ? 78  LEU A N   1 
ATOM   2693 C  CA  . LEU B 2 82  ? -11.932 -11.985 23.178  1   47.86  ? 78  LEU A CA  1 
ATOM   2694 C  C   . LEU B 2 82  ? -12.271 -13.129 24.134  1   49.53  ? 78  LEU A C   1 
ATOM   2695 O  O   . LEU B 2 82  ? -11.353 -13.866 24.51   1   51.91  ? 78  LEU A O   1 
ATOM   2696 C  CB  . LEU B 2 82  ? -11.259 -12.491 21.909  1   44.2   ? 78  LEU A CB  1 
ATOM   2697 C  CG  . LEU B 2 82  ? -10.919 -11.455 20.836  1   43.82  ? 78  LEU A CG  1 
ATOM   2698 C  CD1 . LEU B 2 82  ? -11.009 -12.113 19.476  1   41.21  ? 78  LEU A CD1 1 
ATOM   2699 C  CD2 . LEU B 2 82  ? -11.802 -10.227 20.898  1   45.52  ? 78  LEU A CD2 1 
ATOM   2700 N  N   . VAL B 2 83  ? -13.536 -13.237 24.527  1   47.77  ? 79  VAL A N   1 
ATOM   2701 C  CA  . VAL B 2 83  ? -13.981 -14.304 25.463  1   46.13  ? 79  VAL A CA  1 
ATOM   2702 C  C   . VAL B 2 83  ? -14.47  -15.492 24.633  1   46.58  ? 79  VAL A C   1 
ATOM   2703 O  O   . VAL B 2 83  ? -15.423 -15.32  23.873  1   49.02  ? 79  VAL A O   1 
ATOM   2704 C  CB  . VAL B 2 83  ? -15.087 -13.766 26.382  1   46.64  ? 79  VAL A CB  1 
ATOM   2705 C  CG1 . VAL B 2 83  ? -15.376 -14.71  27.539  1   46.92  ? 79  VAL A CG1 1 
ATOM   2706 C  CG2 . VAL B 2 83  ? -14.776 -12.364 26.885  1   47.51  ? 79  VAL A CG2 1 
ATOM   2707 N  N   . PHE B 2 84  ? -13.81  -16.632 24.763  1   47.3   ? 80  PHE A N   1 
ATOM   2708 C  CA  . PHE B 2 84  ? -14.204 -17.827 23.988  1   45.21  ? 80  PHE A CA  1 
ATOM   2709 C  C   . PHE B 2 84  ? -14.582 -18.916 24.948  1   46.45  ? 80  PHE A C   1 
ATOM   2710 O  O   . PHE B 2 84  ? -14.167 -18.868 26.107  1   49.57  ? 80  PHE A O   1 
ATOM   2711 C  CB  . PHE B 2 84  ? -13.039 -18.355 23.154  1   42.11  ? 80  PHE A CB  1 
ATOM   2712 C  CG  . PHE B 2 84  ? -12.521 -17.518 21.998  1   41.63  ? 80  PHE A CG  1 
ATOM   2713 C  CD1 . PHE B 2 84  ? -11.451 -16.653 22.173  1   41.37  ? 80  PHE A CD1 1 
ATOM   2714 C  CD2 . PHE B 2 84  ? -13.069 -17.642 20.729  1   40.46  ? 80  PHE A CD2 1 
ATOM   2715 C  CE1 . PHE B 2 84  ? -10.965 -15.913 21.111  1   42.61  ? 80  PHE A CE1 1 
ATOM   2716 C  CE2 . PHE B 2 84  ? -12.577 -16.897 19.674  1   38.17  ? 80  PHE A CE2 1 
ATOM   2717 C  CZ  . PHE B 2 84  ? -11.527 -16.036 19.867  1   39.39  ? 80  PHE A CZ  1 
ATOM   2718 N  N   . GLU B 2 85  ? -15.366 -19.88  24.485  1   45.71  ? 81  GLU A N   1 
ATOM   2719 C  CA  . GLU B 2 85  ? -15.669 -21.054 25.329  1   47.08  ? 81  GLU A CA  1 
ATOM   2720 C  C   . GLU B 2 85  ? -14.36  -21.825 25.495  1   49.29  ? 81  GLU A C   1 
ATOM   2721 O  O   . GLU B 2 85  ? -13.595 -21.856 24.536  1   51.75  ? 81  GLU A O   1 
ATOM   2722 C  CB  . GLU B 2 85  ? -16.743 -21.863 24.618  1   49.97  ? 81  GLU A CB  1 
ATOM   2723 C  CG  . GLU B 2 85  ? -16.304 -22.419 23.269  1   57.28  ? 81  GLU A CG  1 
ATOM   2724 C  CD  . GLU B 2 85  ? -17.406 -23.121 22.507  1   59.44  ? 81  GLU A CD  1 
ATOM   2725 O  OE1 . GLU B 2 85  ? -18.425 -23.492 23.118  1   53.56  ? 81  GLU A OE1 1 
ATOM   2726 O  OE2 . GLU B 2 85  ? -17.23  -23.293 21.29   1   60.53  ? 81  GLU A OE2 1 
ATOM   2727 N  N   . PHE B 2 86  ? -14.111 -22.412 26.662  1   50.34  ? 82  PHE A N   1 
ATOM   2728 C  CA  . PHE B 2 86  ? -12.8   -23.065 26.898  1   46.73  ? 82  PHE A CA  1 
ATOM   2729 C  C   . PHE B 2 86  ? -12.81  -24.511 26.445  1   46.18  ? 82  PHE A C   1 
ATOM   2730 O  O   . PHE B 2 86  ? -13.796 -25.225 26.671  1   47.15  ? 82  PHE A O   1 
ATOM   2731 C  CB  . PHE B 2 86  ? -12.383 -22.975 28.366  1   49.35  ? 82  PHE A CB  1 
ATOM   2732 C  CG  . PHE B 2 86  ? -11.178 -23.812 28.765  1   51.3   ? 82  PHE A CG  1 
ATOM   2733 C  CD1 . PHE B 2 86  ? -9.889  -23.349 28.546  1   49.74  ? 82  PHE A CD1 1 
ATOM   2734 C  CD2 . PHE B 2 86  ? -11.339 -25.055 29.364  1   51.43  ? 82  PHE A CD2 1 
ATOM   2735 C  CE1 . PHE B 2 86  ? -8.796  -24.115 28.904  1   51.58  ? 82  PHE A CE1 1 
ATOM   2736 C  CE2 . PHE B 2 86  ? -10.241 -25.814 29.722  1   51.84  ? 82  PHE A CE2 1 
ATOM   2737 C  CZ  . PHE B 2 86  ? -8.973  -25.343 29.492  1   51.71  ? 82  PHE A CZ  1 
ATOM   2738 N  N   . LEU B 2 87  ? -11.72  -24.919 25.803  1   45.7   ? 83  LEU A N   1 
ATOM   2739 C  CA  . LEU B 2 87  ? -11.541 -26.327 25.393  1   44.69  ? 83  LEU A CA  1 
ATOM   2740 C  C   . LEU B 2 87  ? -10.247 -26.783 26.074  1   43.59  ? 83  LEU A C   1 
ATOM   2741 O  O   . LEU B 2 87  ? -9.27   -26.035 25.973  1   43.52  ? 83  LEU A O   1 
ATOM   2742 C  CB  . LEU B 2 87  ? -11.559 -26.445 23.873  1   44.92  ? 83  LEU A CB  1 
ATOM   2743 C  CG  . LEU B 2 87  ? -12.946 -26.311 23.237  1   47.95  ? 83  LEU A CG  1 
ATOM   2744 C  CD1 . LEU B 2 87  ? -13.054 -25.103 22.332  1   48.9   ? 83  LEU A CD1 1 
ATOM   2745 C  CD2 . LEU B 2 87  ? -13.37  -27.568 22.513  1   51.43  ? 83  LEU A CD2 1 
ATOM   2746 N  N   A HIS B 2 88  ? -10.163 -28.045 26.474  0.5 43.02  ? 84  HIS A N   1 
ATOM   2747 N  N   B HIS B 2 88  ? -10.089 -27.977 26.353  0.5 43.76  ? 84  HIS A N   1 
ATOM   2748 C  CA  A HIS B 2 88  ? -9.038  -28.51  27.334  0.5 44.35  ? 84  HIS A CA  1 
ATOM   2749 C  CA  B HIS B 2 88  ? -9.061  -28.451 27.275  0.5 45.6   ? 84  HIS A CA  1 
ATOM   2750 C  C   A HIS B 2 88  ? -7.703  -28.7   26.607  0.5 45.45  ? 84  HIS A C   1 
ATOM   2751 C  C   B HIS B 2 88  ? -7.7    -28.61  26.59   0.5 46.18  ? 84  HIS A C   1 
ATOM   2752 O  O   A HIS B 2 88  ? -6.702  -28.28  27.217  0.5 46.25  ? 84  HIS A O   1 
ATOM   2753 O  O   B HIS B 2 88  ? -6.653  -28.424 27.214  0.5 46.81  ? 84  HIS A O   1 
ATOM   2754 C  CB  A HIS B 2 88  ? -9.502  -29.777 28.058  0.5 43.15  ? 84  HIS A CB  1 
ATOM   2755 C  CB  B HIS B 2 88  ? -9.542  -29.67  28.08   0.5 45.55  ? 84  HIS A CB  1 
ATOM   2756 C  CG  A HIS B 2 88  ? -10.875 -29.611 28.621  0.5 41.72  ? 84  HIS A CG  1 
ATOM   2757 C  CG  B HIS B 2 88  ? -9.268  -31.059 27.561  0.5 44.23  ? 84  HIS A CG  1 
ATOM   2758 N  ND1 A HIS B 2 88  ? -12.025 -29.772 27.879  0.5 38.36  ? 84  HIS A ND1 1 
ATOM   2759 N  ND1 B HIS B 2 88  ? -9.912  -31.676 26.51   0.5 42.44  ? 84  HIS A ND1 1 
ATOM   2760 C  CD2 A HIS B 2 88  ? -11.278 -29.269 29.85   0.5 42.32  ? 84  HIS A CD2 1 
ATOM   2761 C  CD2 B HIS B 2 88  ? -8.424  -31.983 28.037  0.5 45.7   ? 84  HIS A CD2 1 
ATOM   2762 C  CE1 A HIS B 2 88  ? -13.078 -29.536 28.644  0.5 39.09  ? 84  HIS A CE1 1 
ATOM   2763 C  CE1 B HIS B 2 88  ? -9.444  -32.915 26.356  0.5 42.81  ? 84  HIS A CE1 1 
ATOM   2764 N  NE2 A HIS B 2 88  ? -12.647 -29.235 29.848  0.5 41.39  ? 84  HIS A NE2 1 
ATOM   2765 N  NE2 B HIS B 2 88  ? -8.532  -33.123 27.272  0.5 44.91  ? 84  HIS A NE2 1 
ATOM   2766 N  N   . GLN B 2 89  ? -7.71   -28.932 25.298  1   44.86  ? 85  GLN A N   1 
ATOM   2767 C  CA  . GLN B 2 89  ? -6.451  -29.235 24.626  1   46.63  ? 85  GLN A CA  1 
ATOM   2768 C  C   . GLN B 2 89  ? -6.546  -28.933 23.134  1   42.76  ? 85  GLN A C   1 
ATOM   2769 O  O   . GLN B 2 89  ? -7.63   -28.726 22.614  1   45.2   ? 85  GLN A O   1 
ATOM   2770 C  CB  . GLN B 2 89  ? -6.153  -30.713 24.873  1   49.91  ? 85  GLN A CB  1 
ATOM   2771 C  CG  . GLN B 2 89  ? -4.702  -30.985 25.233  1   58.73  ? 85  GLN A CG  1 
ATOM   2772 C  CD  . GLN B 2 89  ? -4.459  -32.469 25.312  1   65.36  ? 85  GLN A CD  1 
ATOM   2773 O  OE1 . GLN B 2 89  ? -3.88   -32.989 26.268  1   75.25  ? 85  GLN A OE1 1 
ATOM   2774 N  NE2 . GLN B 2 89  ? -4.939  -33.177 24.303  1   68.32  ? 85  GLN A NE2 1 
ATOM   2775 N  N   . ASP B 2 90  ? -5.406  -28.931 22.445  1   42.04  ? 86  ASP A N   1 
ATOM   2776 C  CA  . ASP B 2 90  ? -5.363  -28.952 20.992  1   41.43  ? 86  ASP A CA  1 
ATOM   2777 C  C   . ASP B 2 90  ? -4.926  -30.343 20.492  1   42.56  ? 86  ASP A C   1 
ATOM   2778 O  O   . ASP B 2 90  ? -4.363  -31.156 21.223  1   44.77  ? 86  ASP A O   1 
ATOM   2779 C  CB  . ASP B 2 90  ? -4.453  -27.855 20.49   1   42.05  ? 86  ASP A CB  1 
ATOM   2780 C  CG  . ASP B 2 90  ? -2.988  -28.176 20.684  1   45.5   ? 86  ASP A CG  1 
ATOM   2781 O  OD1 . ASP B 2 90  ? -2.46   -29.002 19.956  1   48.86  ? 86  ASP A OD1 1 
ATOM   2782 O  OD2 . ASP B 2 90  ? -2.411  -27.668 21.624  1   56.92  ? 86  ASP A OD2 1 
ATOM   2783 N  N   . LEU B 2 91  ? -5.19   -30.615 19.22   1   39.24  ? 87  LEU A N   1 
ATOM   2784 C  CA  . LEU B 2 91  ? -5.012  -31.934 18.664  1   41.65  ? 87  LEU A CA  1 
ATOM   2785 C  C   . LEU B 2 91  ? -3.526  -32.303 18.627  1   45.8   ? 87  LEU A C   1 
ATOM   2786 O  O   . LEU B 2 91  ? -3.204  -33.484 18.761  1   47.44  ? 87  LEU A O   1 
ATOM   2787 C  CB  . LEU B 2 91  ? -5.639  -31.922 17.266  1   40.22  ? 87  LEU A CB  1 
ATOM   2788 C  CG  . LEU B 2 91  ? -5.531  -33.23  16.473  1   41.94  ? 87  LEU A CG  1 
ATOM   2789 C  CD1 . LEU B 2 91  ? -6.264  -34.379 17.17   1   38.29  ? 87  LEU A CD1 1 
ATOM   2790 C  CD2 . LEU B 2 91  ? -6.055  -33.012 15.046  1   43.31  ? 87  LEU A CD2 1 
ATOM   2791 N  N   . LYS B 2 92  ? -2.638  -31.321 18.397  1   45.86  ? 88  LYS A N   1 
ATOM   2792 C  CA  . LYS B 2 92  ? -1.208  -31.597 18.368  1   50.78  ? 88  LYS A CA  1 
ATOM   2793 C  C   . LYS B 2 92  ? -0.766  -32.201 19.703  1   57.11  ? 88  LYS A C   1 
ATOM   2794 O  O   . LYS B 2 92  ? -0.165  -33.283 19.706  1   59.09  ? 88  LYS A O   1 
ATOM   2795 C  CB  . LYS B 2 92  ? -0.371  -30.38  17.982  1   52.79  ? 88  LYS A CB  1 
ATOM   2796 C  CG  . LYS B 2 92  ? 1.115   -30.488 18.287  1   61.86  ? 88  LYS A CG  1 
ATOM   2797 C  CD  . LYS B 2 92  ? 1.9     -31.606 17.612  1   70.31  ? 88  LYS A CD  1 
ATOM   2798 C  CE  . LYS B 2 92  ? 1.964   -31.408 16.133  1   80.03  ? 88  LYS A CE  1 
ATOM   2799 N  NZ  . LYS B 2 92  ? 2.569   -32.551 15.441  1   86.98  ? 88  LYS A NZ  1 
ATOM   2800 N  N   . LYS B 2 93  ? -1.105  -31.536 20.823  1   54.7   ? 89  LYS A N   1 
ATOM   2801 C  CA  . LYS B 2 93  ? -0.773  -32.025 22.162  1   56.3   ? 89  LYS A CA  1 
ATOM   2802 C  C   . LYS B 2 93  ? -1.354  -33.418 22.42   1   53.46  ? 89  LYS A C   1 
ATOM   2803 O  O   . LYS B 2 93  ? -0.692  -34.248 23.023  1   55.78  ? 89  LYS A O   1 
ATOM   2804 C  CB  . LYS B 2 93  ? -1.159  -31.017 23.253  1   62.32  ? 89  LYS A CB  1 
ATOM   2805 C  CG  . LYS B 2 93  ? -0.262  -29.783 23.259  1   74.32  ? 89  LYS A CG  1 
ATOM   2806 C  CD  . LYS B 2 93  ? -0.623  -28.658 24.219  1   84.14  ? 89  LYS A CD  1 
ATOM   2807 C  CE  . LYS B 2 93  ? 0.397   -27.559 24.108  1   90.8   ? 89  LYS A CE  1 
ATOM   2808 N  NZ  . LYS B 2 93  ? 0.228   -26.505 25.115  1   98     ? 89  LYS A NZ  1 
ATOM   2809 N  N   . PHE B 2 94  ? -2.566  -33.688 21.919  1   48.91  ? 90  PHE A N   1 
ATOM   2810 C  CA  . PHE B 2 94  ? -3.241  -34.964 22.1    1   49.04  ? 90  PHE A CA  1 
ATOM   2811 C  C   . PHE B 2 94  ? -2.55   -36.08  21.31   1   49.71  ? 90  PHE A C   1 
ATOM   2812 O  O   . PHE B 2 94  ? -2.34   -37.165 21.841  1   50.88  ? 90  PHE A O   1 
ATOM   2813 C  CB  . PHE B 2 94  ? -4.721  -34.826 21.725  1   46.52  ? 90  PHE A CB  1 
ATOM   2814 C  CG  . PHE B 2 94  ? -5.516  -36.114 21.857  1   47.58  ? 90  PHE A CG  1 
ATOM   2815 C  CD1 . PHE B 2 94  ? -5.751  -36.666 23.107  1   50.97  ? 90  PHE A CD1 1 
ATOM   2816 C  CD2 . PHE B 2 94  ? -6.008  -36.781 20.738  1   47.01  ? 90  PHE A CD2 1 
ATOM   2817 C  CE1 . PHE B 2 94  ? -6.471  -37.848 23.227  1   51.98  ? 90  PHE A CE1 1 
ATOM   2818 C  CE2 . PHE B 2 94  ? -6.725  -37.968 20.866  1   48.41  ? 90  PHE A CE2 1 
ATOM   2819 C  CZ  . PHE B 2 94  ? -6.95   -38.507 22.11   1   50.12  ? 90  PHE A CZ  1 
ATOM   2820 N  N   . MET B 2 95  ? -2.215  -35.824 20.037  1   47.81  ? 91  MET A N   1 
ATOM   2821 C  CA  . MET B 2 95  ? -1.452  -36.78  19.248  1   50.07  ? 91  MET A CA  1 
ATOM   2822 C  C   . MET B 2 95  ? -0.083  -37.025 19.872  1   56.19  ? 91  MET A C   1 
ATOM   2823 O  O   . MET B 2 95  ? 0.429   -38.124 19.729  1   62.38  ? 91  MET A O   1 
ATOM   2824 C  CB  . MET B 2 95  ? -1.197  -36.305 17.817  1   49.4   ? 91  MET A CB  1 
ATOM   2825 C  CG  . MET B 2 95  ? -2.398  -36.35  16.911  1   48.84  ? 91  MET A CG  1 
ATOM   2826 S  SD  . MET B 2 95  ? -2.049  -35.46  15.38   1   60.72  ? 91  MET A SD  1 
ATOM   2827 C  CE  . MET B 2 95  ? -1.351  -33.898 15.912  1   56.52  ? 91  MET A CE  1 
ATOM   2828 N  N   . ASP B 2 96  ? 0.52    -36.014 20.524  1   56.32  ? 92  ASP A N   1 
ATOM   2829 C  CA  . ASP B 2 96  ? 1.791   -36.223 21.2    1   60.81  ? 92  ASP A CA  1 
ATOM   2830 C  C   . ASP B 2 96  ? 1.583   -37.063 22.455  1   67.72  ? 92  ASP A C   1 
ATOM   2831 O  O   . ASP B 2 96  ? 2.526   -37.703 22.911  1   73.85  ? 92  ASP A O   1 
ATOM   2832 C  CB  . ASP B 2 96  ? 2.496   -34.942 21.628  1   59.17  ? 92  ASP A CB  1 
ATOM   2833 C  CG  . ASP B 2 96  ? 2.955   -34.009 20.52   1   57.38  ? 92  ASP A CG  1 
ATOM   2834 O  OD1 . ASP B 2 96  ? 3.173   -34.51  19.377  1   50.06  ? 92  ASP A OD1 1 
ATOM   2835 O  OD2 . ASP B 2 96  ? 2.996   -32.771 20.802  1   60.65  ? 92  ASP A OD2 1 
ATOM   2836 N  N   . ALA B 2 97  ? 0.37    -37.023 23.031  1   68.79  ? 93  ALA A N   1 
ATOM   2837 C  CA  . ALA B 2 97  ? 0.083   -37.772 24.252  1   69.33  ? 93  ALA A CA  1 
ATOM   2838 C  C   . ALA B 2 97  ? -0.411  -39.185 23.917  1   71.93  ? 93  ALA A C   1 
ATOM   2839 O  O   . ALA B 2 97  ? -0.46   -40.026 24.808  1   69.36  ? 93  ALA A O   1 
ATOM   2840 C  CB  . ALA B 2 97  ? -0.893  -37.006 25.11   1   65.15  ? 93  ALA A CB  1 
ATOM   2841 N  N   . SER B 2 98  ? -0.824  -39.396 22.658  1   72.22  ? 94  SER A N   1 
ATOM   2842 C  CA  . SER B 2 98  ? -1.451  -40.679 22.237  1   75.35  ? 94  SER A CA  1 
ATOM   2843 C  C   . SER B 2 98  ? -0.48   -41.59  21.482  1   93.3   ? 94  SER A C   1 
ATOM   2844 O  O   . SER B 2 98  ? -0.912  -42.676 21.073  1   103.86 ? 94  SER A O   1 
ATOM   2845 C  CB  . SER B 2 98  ? -2.646  -40.428 21.368  1   62.71  ? 94  SER A CB  1 
ATOM   2846 O  OG  . SER B 2 98  ? -3.486  -39.425 21.917  1   66.93  ? 94  SER A OG  1 
ATOM   2847 N  N   . ALA B 2 99  ? 0.779   -41.2   21.32   1   106.84 ? 95  ALA A N   1 
ATOM   2848 C  CA  . ALA B 2 99  ? 1.715   -42.129 20.651  1   110.67 ? 95  ALA A CA  1 
ATOM   2849 C  C   . ALA B 2 99  ? 1.931   -43.364 21.527  1   111.21 ? 95  ALA A C   1 
ATOM   2850 O  O   . ALA B 2 99  ? 1.47    -43.334 22.692  1   126.19 ? 95  ALA A O   1 
ATOM   2851 C  CB  . ALA B 2 99  ? 3.005   -41.429 20.325  1   96.75  ? 95  ALA A CB  1 
ATOM   2852 N  N   . LEU B 2 100 ? 2.572   -44.405 20.983  1   113.7  ? 96  LEU A N   1 
ATOM   2853 C  CA  . LEU B 2 100 ? 2.813   -45.688 21.71   1   126.94 ? 96  LEU A CA  1 
ATOM   2854 C  C   . LEU B 2 100 ? 1.542   -46.548 21.621  1   115.68 ? 96  LEU A C   1 
ATOM   2855 O  O   . LEU B 2 100 ? 1.63    -47.768 21.863  1   105.36 ? 96  LEU A O   1 
ATOM   2856 C  CB  . LEU B 2 100 ? 3.285   -45.524 23.158  1   134.57 ? 96  LEU A CB  1 
ATOM   2857 C  CG  . LEU B 2 100 ? 4.8     -45.453 23.368  1   130.77 ? 96  LEU A CG  1 
ATOM   2858 C  CD1 . LEU B 2 100 ? 5.298   -44.026 23.22   1   113.1  ? 96  LEU A CD1 1 
ATOM   2859 C  CD2 . LEU B 2 100 ? 5.149   -46.003 24.737  1   125.94 ? 96  LEU A CD2 1 
ATOM   2860 N  N   . THR B 2 101 ? 0.414   -45.931 21.285  1   105.47 ? 97  THR A N   1 
ATOM   2861 C  CA  . THR B 2 101 ? -0.841  -46.673 21.113  1   104.84 ? 97  THR A CA  1 
ATOM   2862 C  C   . THR B 2 101 ? -1.455  -46.155 19.853  1   97.17  ? 97  THR A C   1 
ATOM   2863 O  O   . THR B 2 101 ? -2.022  -46.955 19.083  1   100.3  ? 97  THR A O   1 
ATOM   2864 C  CB  . THR B 2 101 ? -1.765  -46.381 22.29   1   114.09 ? 97  THR A CB  1 
ATOM   2865 O  OG1 . THR B 2 101 ? -1.964  -44.971 22.265  1   96.07  ? 97  THR A OG1 1 
ATOM   2866 C  CG2 . THR B 2 101 ? -1.172  -46.783 23.628  1   117.84 ? 97  THR A CG2 1 
ATOM   2867 N  N   . GLY B 2 102 ? -1.346  -44.849 19.645  1   82.33  ? 98  GLY A N   1 
ATOM   2868 C  CA  . GLY B 2 102 ? -2.014  -44.235 18.496  1   67.83  ? 98  GLY A CA  1 
ATOM   2869 C  C   . GLY B 2 102 ? -3.391  -43.778 18.9    1   61.49  ? 98  GLY A C   1 
ATOM   2870 O  O   . GLY B 2 102 ? -3.816  -44.106 20.018  1   65.56  ? 98  GLY A O   1 
ATOM   2871 N  N   . ILE B 2 103 ? -4.05   -43.02  18.034  1   57.97  ? 99  ILE A N   1 
ATOM   2872 C  CA  . ILE B 2 103 ? -5.456  -42.629 18.306  1   54.04  ? 99  ILE A CA  1 
ATOM   2873 C  C   . ILE B 2 103 ? -6.326  -43.763 17.755  1   53.25  ? 99  ILE A C   1 
ATOM   2874 O  O   . ILE B 2 103 ? -6.082  -44.194 16.621  1   52.1   ? 99  ILE A O   1 
ATOM   2875 C  CB  . ILE B 2 103 ? -5.771  -41.269 17.661  1   52.61  ? 99  ILE A CB  1 
ATOM   2876 C  CG1 . ILE B 2 103 ? -4.679  -40.246 17.943  1   51.83  ? 99  ILE A CG1 1 
ATOM   2877 C  CG2 . ILE B 2 103 ? -7.145  -40.757 18.088  1   52.36  ? 99  ILE A CG2 1 
ATOM   2878 C  CD1 . ILE B 2 103 ? -4.93   -38.896 17.301  1   50.06  ? 99  ILE A CD1 1 
ATOM   2879 N  N   . PRO B 2 104 ? -7.367  -44.239 18.481  1   53.01  ? 100 PRO A N   1 
ATOM   2880 C  CA  . PRO B 2 104 ? -8.253  -45.239 17.916  1   52.16  ? 100 PRO A CA  1 
ATOM   2881 C  C   . PRO B 2 104 ? -8.975  -44.721 16.688  1   49.84  ? 100 PRO A C   1 
ATOM   2882 O  O   . PRO B 2 104 ? -9.313  -43.534 16.639  1   49.89  ? 100 PRO A O   1 
ATOM   2883 C  CB  . PRO B 2 104 ? -9.201  -45.485 19.082  1   54.08  ? 100 PRO A CB  1 
ATOM   2884 C  CG  . PRO B 2 104 ? -8.38   -45.193 20.303  1   55.15  ? 100 PRO A CG  1 
ATOM   2885 C  CD  . PRO B 2 104 ? -7.738  -43.906 19.872  1   51.43  ? 100 PRO A CD  1 
ATOM   2886 N  N   . LEU B 2 105 ? -9.222  -45.599 15.719  1   49.9   ? 101 LEU A N   1 
ATOM   2887 C  CA  . LEU B 2 105 ? -9.928  -45.211 14.468  1   48.33  ? 101 LEU A CA  1 
ATOM   2888 C  C   . LEU B 2 105 ? -11.285 -44.568 14.792  1   48.09  ? 101 LEU A C   1 
ATOM   2889 O  O   . LEU B 2 105 ? -11.579 -43.531 14.19   1   45.97  ? 101 LEU A O   1 
ATOM   2890 C  CB  . LEU B 2 105 ? -10.069 -46.401 13.52   1   47.66  ? 101 LEU A CB  1 
ATOM   2891 C  CG  . LEU B 2 105 ? -10.473 -46.063 12.084  1   47.98  ? 101 LEU A CG  1 
ATOM   2892 C  CD1 . LEU B 2 105 ? -9.435  -45.168 11.439  1   50.46  ? 101 LEU A CD1 1 
ATOM   2893 C  CD2 . LEU B 2 105 ? -10.652 -47.337 11.29   1   48.34  ? 101 LEU A CD2 1 
ATOM   2894 N  N   . PRO B 2 106 ? -12.135 -45.123 15.681  1   46.91  ? 102 PRO A N   1 
ATOM   2895 C  CA  . PRO B 2 106 ? -13.368 -44.451 16.042  1   44.38  ? 102 PRO A CA  1 
ATOM   2896 C  C   . PRO B 2 106 ? -13.142 -42.988 16.316  1   44.95  ? 102 PRO A C   1 
ATOM   2897 O  O   . PRO B 2 106 ? -13.938 -42.161 15.859  1   50.89  ? 102 PRO A O   1 
ATOM   2898 C  CB  . PRO B 2 106 ? -13.746 -45.22  17.302  1   45.18  ? 102 PRO A CB  1 
ATOM   2899 C  CG  . PRO B 2 106 ? -13.344 -46.63  16.995  1   47.49  ? 102 PRO A CG  1 
ATOM   2900 C  CD  . PRO B 2 106 ? -12.014 -46.434 16.311  1   47.68  ? 102 PRO A CD  1 
ATOM   2901 N  N   . LEU B 2 107 ? -12.079 -42.67  17.041  1   44.36  ? 103 LEU A N   1 
ATOM   2902 C  CA  . LEU B 2 107 ? -11.813 -41.297 17.42   1   42.4   ? 103 LEU A CA  1 
ATOM   2903 C  C   . LEU B 2 107 ? -11.336 -40.5   16.215  1   42.32  ? 103 LEU A C   1 
ATOM   2904 O  O   . LEU B 2 107 ? -11.768 -39.365 16.032  1   40.34  ? 103 LEU A O   1 
ATOM   2905 C  CB  . LEU B 2 107 ? -10.786 -41.294 18.543  1   44.85  ? 103 LEU A CB  1 
ATOM   2906 C  CG  . LEU B 2 107 ? -10.721 -40.023 19.4    1   46.62  ? 103 LEU A CG  1 
ATOM   2907 C  CD1 . LEU B 2 107 ? -12.093 -39.399 19.663  1   44.81  ? 103 LEU A CD1 1 
ATOM   2908 C  CD2 . LEU B 2 107 ? -10.081 -40.419 20.735  1   49.7   ? 103 LEU A CD2 1 
ATOM   2909 N  N   . ILE B 2 108 ? -10.466 -41.106 15.386  1   43.1   ? 104 ILE A N   1 
ATOM   2910 C  CA  . ILE B 2 108 ? -9.962  -40.459 14.185  1   42.27  ? 104 ILE A CA  1 
ATOM   2911 C  C   . ILE B 2 108 ? -11.154 -40.072 13.303  1   43.93  ? 104 ILE A C   1 
ATOM   2912 O  O   . ILE B 2 108 ? -11.251 -38.973 12.746  1   43.92  ? 104 ILE A O   1 
ATOM   2913 C  CB  . ILE B 2 108 ? -9      -41.418 13.459  1   44.15  ? 104 ILE A CB  1 
ATOM   2914 C  CG1 . ILE B 2 108 ? -7.658  -41.588 14.193  1   44.33  ? 104 ILE A CG1 1 
ATOM   2915 C  CG2 . ILE B 2 108 ? -8.765  -40.959 12.025  1   42.93  ? 104 ILE A CG2 1 
ATOM   2916 C  CD1 . ILE B 2 108 ? -6.787  -42.702 13.623  1   40.66  ? 104 ILE A CD1 1 
ATOM   2917 N  N   . LYS B 2 109 ? -12.07  -41.025 13.181  1   44.5   ? 105 LYS A N   1 
ATOM   2918 C  CA  . LYS B 2 109 ? -13.212 -40.931 12.297  1   43.52  ? 105 LYS A CA  1 
ATOM   2919 C  C   . LYS B 2 109 ? -14.18  -39.853 12.784  1   43.69  ? 105 LYS A C   1 
ATOM   2920 O  O   . LYS B 2 109 ? -14.712 -39.096 11.972  1   42.62  ? 105 LYS A O   1 
ATOM   2921 C  CB  . LYS B 2 109 ? -13.842 -42.324 12.274  1   43.03  ? 105 LYS A CB  1 
ATOM   2922 C  CG  . LYS B 2 109 ? -14.212 -42.808 10.906  1   43.36  ? 105 LYS A CG  1 
ATOM   2923 C  CD  . LYS B 2 109 ? -14.808 -44.205 10.955  1   46.15  ? 105 LYS A CD  1 
ATOM   2924 C  CE  . LYS B 2 109 ? -13.87  -45.246 10.505  1   47.1   ? 105 LYS A CE  1 
ATOM   2925 N  NZ  . LYS B 2 109 ? -14.627 -46.468 10.243  1   55.5   ? 105 LYS A NZ  1 
ATOM   2926 N  N   . SER B 2 110 ? -14.425 -39.818 14.102  1   44.45  ? 106 SER A N   1 
ATOM   2927 C  CA  . SER B 2 110 ? -15.279 -38.825 14.739  1   44.08  ? 106 SER A CA  1 
ATOM   2928 C  C   . SER B 2 110 ? -14.666 -37.446 14.543  1   42.47  ? 106 SER A C   1 
ATOM   2929 O  O   . SER B 2 110 ? -15.356 -36.487 14.2    1   45     ? 106 SER A O   1 
ATOM   2930 C  CB  . SER B 2 110 ? -15.484 -39.131 16.2    1   47.47  ? 106 SER A CB  1 
ATOM   2931 O  OG  . SER B 2 110 ? -16.016 -38.037 16.943  1   54.86  ? 106 SER A OG  1 
ATOM   2932 N  N   . TYR B 2 111 ? -13.346 -37.373 14.71   1   41.67  ? 107 TYR A N   1 
ATOM   2933 C  CA  . TYR B 2 111 ? -12.684 -36.08  14.686  1   42.83  ? 107 TYR A CA  1 
ATOM   2934 C  C   . TYR B 2 111 ? -12.7   -35.531 13.265  1   41.63  ? 107 TYR A C   1 
ATOM   2935 O  O   . TYR B 2 111 ? -12.896 -34.327 13.088  1   39.85  ? 107 TYR A O   1 
ATOM   2936 C  CB  . TYR B 2 111 ? -11.259 -36.108 15.238  1   41.26  ? 107 TYR A CB  1 
ATOM   2937 C  CG  . TYR B 2 111 ? -11.139 -36.054 16.754  1   40.04  ? 107 TYR A CG  1 
ATOM   2938 C  CD1 . TYR B 2 111 ? -12.251 -35.877 17.591  1   38.28  ? 107 TYR A CD1 1 
ATOM   2939 C  CD2 . TYR B 2 111 ? -9.887  -36.199 17.337  1   36.96  ? 107 TYR A CD2 1 
ATOM   2940 C  CE1 . TYR B 2 111 ? -12.098 -35.846 18.974  1   39.67  ? 107 TYR A CE1 1 
ATOM   2941 C  CE2 . TYR B 2 111 ? -9.721  -36.108 18.705  1   38.32  ? 107 TYR A CE2 1 
ATOM   2942 C  CZ  . TYR B 2 111 ? -10.826 -35.943 19.52   1   40.19  ? 107 TYR A CZ  1 
ATOM   2943 O  OH  . TYR B 2 111 ? -10.595 -35.876 20.849  1   43.33  ? 107 TYR A OH  1 
ATOM   2944 N  N   . LEU B 2 112 ? -12.524 -36.422 12.277  1   39.11  ? 108 LEU A N   1 
ATOM   2945 C  CA  . LEU B 2 112 ? -12.442 -35.961 10.902  1   40.57  ? 108 LEU A CA  1 
ATOM   2946 C  C   . LEU B 2 112 ? -13.829 -35.505 10.424  1   45.29  ? 108 LEU A C   1 
ATOM   2947 O  O   . LEU B 2 112 ? -13.989 -34.4   9.879   1   44.03  ? 108 LEU A O   1 
ATOM   2948 C  CB  . LEU B 2 112 ? -11.863 -37.055 10.014  1   35.87  ? 108 LEU A CB  1 
ATOM   2949 C  CG  . LEU B 2 112 ? -11.738 -36.653 8.544   1   34.69  ? 108 LEU A CG  1 
ATOM   2950 C  CD1 . LEU B 2 112 ? -10.883 -35.387 8.48    1   32.65  ? 108 LEU A CD1 1 
ATOM   2951 C  CD2 . LEU B 2 112 ? -11.181 -37.776 7.693   1   32.37  ? 108 LEU A CD2 1 
ATOM   2952 N  N   . PHE B 2 113 ? -14.826 -36.377 10.652  1   43.15  ? 109 PHE A N   1 
ATOM   2953 C  CA  . PHE B 2 113 ? -16.215 -36.048 10.394  1   40.76  ? 109 PHE A CA  1 
ATOM   2954 C  C   . PHE B 2 113 ? -16.572 -34.689 10.997  1   39.76  ? 109 PHE A C   1 
ATOM   2955 O  O   . PHE B 2 113 ? -17.197 -33.87  10.334  1   39.08  ? 109 PHE A O   1 
ATOM   2956 C  CB  . PHE B 2 113 ? -17.135 -37.106 10.99   1   40.6   ? 109 PHE A CB  1 
ATOM   2957 C  CG  . PHE B 2 113 ? -18.513 -37.156 10.352  1   39.31  ? 109 PHE A CG  1 
ATOM   2958 C  CD1 . PHE B 2 113 ? -18.663 -37.323 8.98    1   36.92  ? 109 PHE A CD1 1 
ATOM   2959 C  CD2 . PHE B 2 113 ? -19.655 -37.053 11.14   1   40.88  ? 109 PHE A CD2 1 
ATOM   2960 C  CE1 . PHE B 2 113 ? -19.924 -37.358 8.404   1   38.14  ? 109 PHE A CE1 1 
ATOM   2961 C  CE2 . PHE B 2 113 ? -20.92  -37.14  10.573  1   42.26  ? 109 PHE A CE2 1 
ATOM   2962 C  CZ  . PHE B 2 113 ? -21.05  -37.291 9.208   1   41.24  ? 109 PHE A CZ  1 
ATOM   2963 N  N   . GLN B 2 114 ? -16.159 -34.42  12.238  1   38.62  ? 110 GLN A N   1 
ATOM   2964 C  CA  . GLN B 2 114 ? -16.55  -33.148 12.827  1   38.16  ? 110 GLN A CA  1 
ATOM   2965 C  C   . GLN B 2 114 ? -15.828 -31.998 12.13   1   38.52  ? 110 GLN A C   1 
ATOM   2966 O  O   . GLN B 2 114 ? -16.419 -30.923 11.93   1   37.3   ? 110 GLN A O   1 
ATOM   2967 C  CB  . GLN B 2 114 ? -16.322 -33.114 14.328  1   36.24  ? 110 GLN A CB  1 
ATOM   2968 C  CG  . GLN B 2 114 ? -17.272 -33.99  15.112  1   37.94  ? 110 GLN A CG  1 
ATOM   2969 C  CD  . GLN B 2 114 ? -16.875 -34.009 16.567  1   42.68  ? 110 GLN A CD  1 
ATOM   2970 O  OE1 . GLN B 2 114 ? -17.046 -33.011 17.284  1   44.02  ? 110 GLN A OE1 1 
ATOM   2971 N  NE2 . GLN B 2 114 ? -16.345 -35.138 17.019  1   40.16  ? 110 GLN A NE2 1 
ATOM   2972 N  N   . LEU B 2 115 ? -14.558 -32.234 11.763  1   34.87  ? 111 LEU A N   1 
ATOM   2973 C  CA  . LEU B 2 115 ? -13.812 -31.172 11.118  1   35.35  ? 111 LEU A CA  1 
ATOM   2974 C  C   . LEU B 2 115 ? -14.514 -30.777 9.821   1   35.32  ? 111 LEU A C   1 
ATOM   2975 O  O   . LEU B 2 115 ? -14.721 -29.588 9.543   1   34.19  ? 111 LEU A O   1 
ATOM   2976 C  CB  . LEU B 2 115 ? -12.355 -31.584 10.919  1   35.73  ? 111 LEU A CB  1 
ATOM   2977 C  CG  . LEU B 2 115 ? -11.571 -31.703 12.232  1   37.81  ? 111 LEU A CG  1 
ATOM   2978 C  CD1 . LEU B 2 115 ? -10.311 -32.532 12.05   1   35.95  ? 111 LEU A CD1 1 
ATOM   2979 C  CD2 . LEU B 2 115 ? -11.26  -30.35  12.842  1   34.4   ? 111 LEU A CD2 1 
ATOM   2980 N  N   . LEU B 2 116 ? -14.916 -31.802 9.059   1   34.73  ? 112 LEU A N   1 
ATOM   2981 C  CA  . LEU B 2 116 ? -15.598 -31.605 7.791   1   34.32  ? 112 LEU A CA  1 
ATOM   2982 C  C   . LEU B 2 116 ? -16.911 -30.856 7.993   1   36.32  ? 112 LEU A C   1 
ATOM   2983 O  O   . LEU B 2 116 ? -17.218 -29.987 7.188   1   41.79  ? 112 LEU A O   1 
ATOM   2984 C  CB  . LEU B 2 116 ? -15.739 -32.91  7.019   1   33.36  ? 112 LEU A CB  1 
ATOM   2985 C  CG  . LEU B 2 116 ? -14.42  -33.454 6.45    1   36.11  ? 112 LEU A CG  1 
ATOM   2986 C  CD1 . LEU B 2 116 ? -14.526 -34.942 6.149   1   34.7   ? 112 LEU A CD1 1 
ATOM   2987 C  CD2 . LEU B 2 116 ? -13.915 -32.654 5.223   1   33.23  ? 112 LEU A CD2 1 
ATOM   2988 N  N   . GLN B 2 117 ? -17.622 -31.097 9.104   1   34.89  ? 113 GLN A N   1 
ATOM   2989 C  CA  . GLN B 2 117 ? -18.866 -30.379 9.327   1   35.83  ? 113 GLN A CA  1 
ATOM   2990 C  C   . GLN B 2 117 ? -18.605 -28.891 9.545   1   39.15  ? 113 GLN A C   1 
ATOM   2991 O  O   . GLN B 2 117 ? -19.356 -28.04  9.048   1   40.88  ? 113 GLN A O   1 
ATOM   2992 C  CB  . GLN B 2 117 ? -19.607 -30.906 10.54   1   35.48  ? 113 GLN A CB  1 
ATOM   2993 C  CG  . GLN B 2 117 ? -20.054 -32.351 10.388  1   37.97  ? 113 GLN A CG  1 
ATOM   2994 C  CD  . GLN B 2 117 ? -20.915 -32.773 11.554  1   42.15  ? 113 GLN A CD  1 
ATOM   2995 O  OE1 . GLN B 2 117 ? -21.827 -32.062 12.009  1   44.41  ? 113 GLN A OE1 1 
ATOM   2996 N  NE2 . GLN B 2 117 ? -20.575 -33.933 12.07   1   43.2   ? 113 GLN A NE2 1 
ATOM   2997 N  N   . GLY B 2 118 ? -17.526 -28.591 10.29   1   39.84  ? 114 GLY A N   1 
ATOM   2998 C  CA  . GLY B 2 118 ? -17.211 -27.226 10.684  1   37.5   ? 114 GLY A CA  1 
ATOM   2999 C  C   . GLY B 2 118 ? -16.689 -26.431 9.496   1   40.42  ? 114 GLY A C   1 
ATOM   3000 O  O   . GLY B 2 118 ? -17.036 -25.261 9.308   1   37.56  ? 114 GLY A O   1 
ATOM   3001 N  N   . LEU B 2 119 ? -15.855 -27.099 8.69    1   42.81  ? 115 LEU A N   1 
ATOM   3002 C  CA  . LEU B 2 119 ? -15.295 -26.473 7.508   1   41.26  ? 115 LEU A CA  1 
ATOM   3003 C  C   . LEU B 2 119 ? -16.407 -26.28  6.478   1   43.13  ? 115 LEU A C   1 
ATOM   3004 O  O   . LEU B 2 119 ? -16.498 -25.21  5.866   1   42.36  ? 115 LEU A O   1 
ATOM   3005 C  CB  . LEU B 2 119 ? -14.159 -27.343 6.986   1   38.14  ? 115 LEU A CB  1 
ATOM   3006 C  CG  . LEU B 2 119 ? -13.431 -26.792 5.76    1   39.38  ? 115 LEU A CG  1 
ATOM   3007 C  CD1 . LEU B 2 119 ? -12.742 -25.455 6.071   1   37.09  ? 115 LEU A CD1 1 
ATOM   3008 C  CD2 . LEU B 2 119 ? -12.405 -27.809 5.271   1   38.5   ? 115 LEU A CD2 1 
ATOM   3009 N  N   . ALA B 2 120 ? -17.268 -27.302 6.315   1   39.24  ? 116 ALA A N   1 
ATOM   3010 C  CA  . ALA B 2 120 ? -18.398 -27.168 5.407   1   41     ? 116 ALA A CA  1 
ATOM   3011 C  C   . ALA B 2 120 ? -19.222 -25.927 5.777   1   39.67  ? 116 ALA A C   1 
ATOM   3012 O  O   . ALA B 2 120 ? -19.551 -25.104 4.93    1   42.86  ? 116 ALA A O   1 
ATOM   3013 C  CB  . ALA B 2 120 ? -19.25  -28.422 5.426   1   41.14  ? 116 ALA A CB  1 
ATOM   3014 N  N   . PHE B 2 121 ? -19.549 -25.775 7.057   1   35.23  ? 117 PHE A N   1 
ATOM   3015 C  CA  . PHE B 2 121 ? -20.286 -24.607 7.485   1   35.16  ? 117 PHE A CA  1 
ATOM   3016 C  C   . PHE B 2 121 ? -19.519 -23.317 7.188   1   38.39  ? 117 PHE A C   1 
ATOM   3017 O  O   . PHE B 2 121 ? -20.162 -22.315 6.857   1   43.56  ? 117 PHE A O   1 
ATOM   3018 C  CB  . PHE B 2 121 ? -20.599 -24.734 8.974   1   33.34  ? 117 PHE A CB  1 
ATOM   3019 C  CG  . PHE B 2 121 ? -21.47  -23.618 9.536   1   34.64  ? 117 PHE A CG  1 
ATOM   3020 C  CD1 . PHE B 2 121 ? -20.897 -22.407 9.94    1   33.66  ? 117 PHE A CD1 1 
ATOM   3021 C  CD2 . PHE B 2 121 ? -22.843 -23.816 9.745   1   32.93  ? 117 PHE A CD2 1 
ATOM   3022 C  CE1 . PHE B 2 121 ? -21.685 -21.408 10.508  1   35.43  ? 117 PHE A CE1 1 
ATOM   3023 C  CE2 . PHE B 2 121 ? -23.631 -22.809 10.307  1   33.82  ? 117 PHE A CE2 1 
ATOM   3024 C  CZ  . PHE B 2 121 ? -23.06  -21.61  10.701  1   35.1   ? 117 PHE A CZ  1 
ATOM   3025 N  N   . CYS B 2 122 ? -18.178 -23.318 7.351   1   35.91  ? 118 CYS A N   1 
ATOM   3026 C  CA  . CYS B 2 122 ? -17.357 -22.143 7.047   1   36.08  ? 118 CYS A CA  1 
ATOM   3027 C  C   . CYS B 2 122 ? -17.527 -21.722 5.588   1   37.17  ? 118 CYS A C   1 
ATOM   3028 O  O   . CYS B 2 122 ? -17.835 -20.56  5.3     1   37.14  ? 118 CYS A O   1 
ATOM   3029 C  CB  . CYS B 2 122 ? -15.865 -22.374 7.28    1   35.75  ? 118 CYS A CB  1 
ATOM   3030 S  SG  . CYS B 2 122 ? -15.424 -22.277 9.034   1   39.84  ? 118 CYS A SG  1 
ATOM   3031 N  N   . HIS B 2 123 ? -17.326 -22.698 4.691   1   34.84  ? 119 HIS A N   1 
ATOM   3032 C  CA  . HIS B 2 123 ? -17.471 -22.516 3.258   1   36.87  ? 119 HIS A CA  1 
ATOM   3033 C  C   . HIS B 2 123 ? -18.9   -22.121 2.849   1   39.08  ? 119 HIS A C   1 
ATOM   3034 O  O   . HIS B 2 123 ? -19.084 -21.358 1.892   1   41.61  ? 119 HIS A O   1 
ATOM   3035 C  CB  . HIS B 2 123 ? -16.965 -23.775 2.555   1   35.45  ? 119 HIS A CB  1 
ATOM   3036 C  CG  . HIS B 2 123 ? -15.525 -24.008 2.811   1   36.17  ? 119 HIS A CG  1 
ATOM   3037 N  ND1 . HIS B 2 123 ? -14.882 -25.182 2.472   1   34.32  ? 119 HIS A ND1 1 
ATOM   3038 C  CD2 . HIS B 2 123 ? -14.589 -23.169 3.347   1   37.21  ? 119 HIS A CD2 1 
ATOM   3039 C  CE1 . HIS B 2 123 ? -13.599 -25.042 2.797   1   40.03  ? 119 HIS A CE1 1 
ATOM   3040 N  NE2 . HIS B 2 123 ? -13.393 -23.834 3.353   1   37.52  ? 119 HIS A NE2 1 
ATOM   3041 N  N   . SER B 2 124 ? -19.913 -22.644 3.547   1   35.42  ? 120 SER A N   1 
ATOM   3042 C  CA  . SER B 2 124 ? -21.282 -22.249 3.265   1   40.67  ? 120 SER A CA  1 
ATOM   3043 C  C   . SER B 2 124 ? -21.508 -20.799 3.692   1   42.44  ? 120 SER A C   1 
ATOM   3044 O  O   . SER B 2 124 ? -22.441 -20.148 3.225   1   43.71  ? 120 SER A O   1 
ATOM   3045 C  CB  . SER B 2 124 ? -22.29  -23.184 3.902   1   41.42  ? 120 SER A CB  1 
ATOM   3046 O  OG  . SER B 2 124 ? -22.182 -24.506 3.372   1   45.15  ? 120 SER A OG  1 
ATOM   3047 N  N   . HIS B 2 125 ? -20.632 -20.279 4.56    1   40.12  ? 121 HIS A N   1 
ATOM   3048 C  CA  . HIS B 2 125 ? -20.749 -18.883 4.951   1   41.17  ? 121 HIS A CA  1 
ATOM   3049 C  C   . HIS B 2 125 ? -19.632 -18.014 4.373   1   40.58  ? 121 HIS A C   1 
ATOM   3050 O  O   . HIS B 2 125 ? -19.294 -16.98  4.95    1   39.62  ? 121 HIS A O   1 
ATOM   3051 C  CB  . HIS B 2 125 ? -20.839 -18.771 6.466   1   39.82  ? 121 HIS A CB  1 
ATOM   3052 C  CG  . HIS B 2 125 ? -22.085 -19.424 6.911   1   44.8   ? 121 HIS A CG  1 
ATOM   3053 N  ND1 . HIS B 2 125 ? -22.187 -20.791 7.068   1   44.56  ? 121 HIS A ND1 1 
ATOM   3054 C  CD2 . HIS B 2 125 ? -23.283 -18.913 7.201   1   45.94  ? 121 HIS A CD2 1 
ATOM   3055 C  CE1 . HIS B 2 125 ? -23.414 -21.085 7.463   1   45.78  ? 121 HIS A CE1 1 
ATOM   3056 N  NE2 . HIS B 2 125 ? -24.085 -19.961 7.568   1   46.47  ? 121 HIS A NE2 1 
ATOM   3057 N  N   . ARG B 2 126 ? -19.149 -18.373 3.182   1   37.35  ? 122 ARG A N   1 
ATOM   3058 C  CA  . ARG B 2 126 ? -18.113 -17.561 2.48    1   37.17  ? 122 ARG A CA  1 
ATOM   3059 C  C   . ARG B 2 126 ? -16.902 -17.28  3.385   1   38.12  ? 122 ARG A C   1 
ATOM   3060 O  O   . ARG B 2 126 ? -16.365 -16.156 3.296   1   39.23  ? 122 ARG A O   1 
ATOM   3061 C  CB  . ARG B 2 126 ? -18.618 -16.232 1.897   1   38.01  ? 122 ARG A CB  1 
ATOM   3062 C  CG  . ARG B 2 126 ? -20.089 -15.858 2.001   1   37.2   ? 122 ARG A CG  1 
ATOM   3063 C  CD  . ARG B 2 126 ? -20.226 -14.503 2.665   1   38.88  ? 122 ARG A CD  1 
ATOM   3064 N  NE  . ARG B 2 126 ? -20.438 -14.616 4.112   1   47.69  ? 122 ARG A NE  1 
ATOM   3065 C  CZ  . ARG B 2 126 ? -19.876 -13.824 5.014   1   47.61  ? 122 ARG A CZ  1 
ATOM   3066 N  NH1 . ARG B 2 126 ? -18.665 -14.097 5.465   1   44.86  ? 122 ARG A NH1 1 
ATOM   3067 N  NH2 . ARG B 2 126 ? -20.526 -12.764 5.459   1   43.63  ? 122 ARG A NH2 1 
ATOM   3068 N  N   . VAL B 2 127 ? -16.482 -18.242 4.212   1   37.47  ? 123 VAL A N   1 
ATOM   3069 C  CA  . VAL B 2 127 ? -15.251 -18.067 4.968   1   37.77  ? 123 VAL A CA  1 
ATOM   3070 C  C   . VAL B 2 127 ? -14.221 -19.152 4.631   1   39.29  ? 123 VAL A C   1 
ATOM   3071 O  O   . VAL B 2 127 ? -14.514 -20.35  4.687   1   39.57  ? 123 VAL A O   1 
ATOM   3072 C  CB  . VAL B 2 127 ? -15.543 -18.006 6.476   1   37.05  ? 123 VAL A CB  1 
ATOM   3073 C  CG1 . VAL B 2 127 ? -14.245 -18.01  7.303   1   35.16  ? 123 VAL A CG1 1 
ATOM   3074 C  CG2 . VAL B 2 127 ? -16.378 -16.766 6.802   1   35.24  ? 123 VAL A CG2 1 
ATOM   3075 N  N   . LEU B 2 128 ? -12.998 -18.713 4.31    1   37.2   ? 124 LEU A N   1 
ATOM   3076 C  CA  . LEU B 2 128 ? -11.832 -19.59  4.253   1   34.55  ? 124 LEU A CA  1 
ATOM   3077 C  C   . LEU B 2 128 ? -11.1   -19.537 5.6     1   35.88  ? 124 LEU A C   1 
ATOM   3078 O  O   . LEU B 2 128 ? -10.899 -18.454 6.17    1   36.67  ? 124 LEU A O   1 
ATOM   3079 C  CB  . LEU B 2 128 ? -10.884 -19.147 3.136   1   33.92  ? 124 LEU A CB  1 
ATOM   3080 C  CG  . LEU B 2 128 ? -11.426 -19.173 1.709   1   34.52  ? 124 LEU A CG  1 
ATOM   3081 C  CD1 . LEU B 2 128 ? -10.313 -18.903 0.75    1   34.77  ? 124 LEU A CD1 1 
ATOM   3082 C  CD2 . LEU B 2 128 ? -11.986 -20.523 1.423   1   34.06  ? 124 LEU A CD2 1 
ATOM   3083 N  N   . HIS B 2 129 ? -10.649 -20.702 6.088   1   33.95  ? 125 HIS A N   1 
ATOM   3084 C  CA  . HIS B 2 129 ? -9.931  -20.726 7.346   1   33.69  ? 125 HIS A CA  1 
ATOM   3085 C  C   . HIS B 2 129 ? -8.489  -20.267 7.126   1   36.39  ? 125 HIS A C   1 
ATOM   3086 O  O   . HIS B 2 129 ? -8.008  -19.347 7.799   1   37.4   ? 125 HIS A O   1 
ATOM   3087 C  CB  . HIS B 2 129 ? -10.066 -22.09  8.02    1   30.79  ? 125 HIS A CB  1 
ATOM   3088 C  CG  . HIS B 2 129 ? -9.435  -22.031 9.364   1   34.95  ? 125 HIS A CG  1 
ATOM   3089 N  ND1 . HIS B 2 129 ? -8.066  -22.123 9.523   1   36.35  ? 125 HIS A ND1 1 
ATOM   3090 C  CD2 . HIS B 2 129 ? -9.935  -21.811 10.601  1   37.81  ? 125 HIS A CD2 1 
ATOM   3091 C  CE1 . HIS B 2 129 ? -7.752  -22.008 10.808  1   37.43  ? 125 HIS A CE1 1 
ATOM   3092 N  NE2 . HIS B 2 129 ? -8.869  -21.818 11.491  1   39.07  ? 125 HIS A NE2 1 
ATOM   3093 N  N   . ARG B 2 130 ? -7.794  -20.982 6.227   1   36.04  ? 126 ARG A N   1 
ATOM   3094 C  CA  . ARG B 2 130 ? -6.482  -20.594 5.722   1   36.7   ? 126 ARG A CA  1 
ATOM   3095 C  C   . ARG B 2 130 ? -5.386  -20.811 6.771   1   39.26  ? 126 ARG A C   1 
ATOM   3096 O  O   . ARG B 2 130 ? -4.301  -20.244 6.633   1   44.32  ? 126 ARG A O   1 
ATOM   3097 C  CB  . ARG B 2 130 ? -6.401  -19.16  5.178   1   33.42  ? 126 ARG A CB  1 
ATOM   3098 C  CG  . ARG B 2 130 ? -7.363  -18.82  4.047   1   33.05  ? 126 ARG A CG  1 
ATOM   3099 C  CD  . ARG B 2 130 ? -6.993  -17.592 3.22    1   32.26  ? 126 ARG A CD  1 
ATOM   3100 N  NE  . ARG B 2 130 ? -6.996  -16.435 4.11    1   33.86  ? 126 ARG A NE  1 
ATOM   3101 C  CZ  . ARG B 2 130 ? -6.548  -15.23  3.784   1   36.78  ? 126 ARG A CZ  1 
ATOM   3102 N  NH1 . ARG B 2 130 ? -6.209  -14.947 2.528   1   36.23  ? 126 ARG A NH1 1 
ATOM   3103 N  NH2 . ARG B 2 130 ? -6.494  -14.284 4.717   1   36.06  ? 126 ARG A NH2 1 
ATOM   3104 N  N   . ASP B 2 131 ? -5.631  -21.646 7.795   1   37.25  ? 127 ASP A N   1 
ATOM   3105 C  CA  . ASP B 2 131 ? -4.546  -22.09  8.654   1   36.52  ? 127 ASP A CA  1 
ATOM   3106 C  C   . ASP B 2 131 ? -4.933  -23.378 9.364   1   36.73  ? 127 ASP A C   1 
ATOM   3107 O  O   . ASP B 2 131 ? -4.634  -23.52  10.541  1   38.17  ? 127 ASP A O   1 
ATOM   3108 C  CB  . ASP B 2 131 ? -4.162  -21.069 9.721   1   37.88  ? 127 ASP A CB  1 
ATOM   3109 C  CG  . ASP B 2 131 ? -2.728  -21.175 10.232  1   40.91  ? 127 ASP A CG  1 
ATOM   3110 O  OD1 . ASP B 2 131 ? -1.944  -21.957 9.689   1   44.32  ? 127 ASP A OD1 1 
ATOM   3111 O  OD2 . ASP B 2 131 ? -2.375  -20.45  11.142  1   44.18  ? 127 ASP A OD2 1 
ATOM   3112 N  N   . LEU B 2 132 ? -5.6    -24.308 8.677   1   35.5   ? 128 LEU A N   1 
ATOM   3113 C  CA  . LEU B 2 132 ? -5.97   -25.549 9.337   1   37.86  ? 128 LEU A CA  1 
ATOM   3114 C  C   . LEU B 2 132 ? -4.724  -26.395 9.631   1   40.31  ? 128 LEU A C   1 
ATOM   3115 O  O   . LEU B 2 132 ? -3.986  -26.811 8.733   1   42.14  ? 128 LEU A O   1 
ATOM   3116 C  CB  . LEU B 2 132 ? -6.953  -26.242 8.401   1   39.13  ? 128 LEU A CB  1 
ATOM   3117 C  CG  . LEU B 2 132 ? -8.339  -25.598 8.362   1   41.5   ? 128 LEU A CG  1 
ATOM   3118 C  CD1 . LEU B 2 132 ? -9.249  -26.446 7.496   1   38.04  ? 128 LEU A CD1 1 
ATOM   3119 C  CD2 . LEU B 2 132 ? -8.916  -25.344 9.785   1   38.71  ? 128 LEU A CD2 1 
ATOM   3120 N  N   . LYS B 2 133 ? -4.473  -26.609 10.917  1   37.28  ? 129 LYS A N   1 
ATOM   3121 C  CA  . LYS B 2 133 ? -3.406  -27.464 11.374  1   36.81  ? 129 LYS A CA  1 
ATOM   3122 C  C   . LYS B 2 133 ? -3.771  -27.895 12.784  1   42.51  ? 129 LYS A C   1 
ATOM   3123 O  O   . LYS B 2 133 ? -4.601  -27.249 13.426  1   47.59  ? 129 LYS A O   1 
ATOM   3124 C  CB  . LYS B 2 133 ? -2.09   -26.688 11.403  1   37.64  ? 129 LYS A CB  1 
ATOM   3125 C  CG  . LYS B 2 133 ? -2.121  -25.418 12.217  1   39.61  ? 129 LYS A CG  1 
ATOM   3126 C  CD  . LYS B 2 133 ? -0.735  -24.835 12.434  1   41.97  ? 129 LYS A CD  1 
ATOM   3127 C  CE  . LYS B 2 133 ? -0.745  -23.418 12.942  1   40.92  ? 129 LYS A CE  1 
ATOM   3128 N  NZ  . LYS B 2 133 ? 0.632   -22.925 12.881  1   40.23  ? 129 LYS A NZ  1 
ATOM   3129 N  N   . PRO B 2 134 ? -3.213  -29.02  13.31   1   46.13  ? 130 PRO A N   1 
ATOM   3130 C  CA  . PRO B 2 134 ? -3.643  -29.559 14.597  1   45.3   ? 130 PRO A CA  1 
ATOM   3131 C  C   . PRO B 2 134 ? -3.592  -28.642 15.799  1   49.42  ? 130 PRO A C   1 
ATOM   3132 O  O   . PRO B 2 134 ? -4.378  -28.822 16.732  1   52.96  ? 130 PRO A O   1 
ATOM   3133 C  CB  . PRO B 2 134 ? -2.663  -30.727 14.747  1   44.19  ? 130 PRO A CB  1 
ATOM   3134 C  CG  . PRO B 2 134 ? -2.436  -31.2   13.349  1   41.65  ? 130 PRO A CG  1 
ATOM   3135 C  CD  . PRO B 2 134 ? -2.137  -29.863 12.74   1   43.17  ? 130 PRO A CD  1 
ATOM   3136 N  N   . GLN B 2 135 ? -2.689  -27.672 15.774  1   46.76  ? 131 GLN A N   1 
ATOM   3137 C  CA  . GLN B 2 135 ? -2.521  -26.745 16.912  1   45.5   ? 131 GLN A CA  1 
ATOM   3138 C  C   . GLN B 2 135 ? -3.693  -25.766 16.945  1   42.83  ? 131 GLN A C   1 
ATOM   3139 O  O   . GLN B 2 135 ? -3.934  -25.174 18.003  1   42.03  ? 131 GLN A O   1 
ATOM   3140 C  CB  . GLN B 2 135 ? -1.184  -26.053 16.68   1   51.27  ? 131 GLN A CB  1 
ATOM   3141 C  CG  . GLN B 2 135 ? 0.024   -26.974 16.794  1   58.35  ? 131 GLN A CG  1 
ATOM   3142 C  CD  . GLN B 2 135 ? 0.514   -27.511 15.467  1   59.05  ? 131 GLN A CD  1 
ATOM   3143 O  OE1 . GLN B 2 135 ? -0.215  -27.552 14.473  1   62.32  ? 131 GLN A OE1 1 
ATOM   3144 N  NE2 . GLN B 2 135 ? 1.764   -27.944 15.446  1   52.25  ? 131 GLN A NE2 1 
ATOM   3145 N  N   . ASN B 2 136 ? -4.382  -25.611 15.819  1   38.31  ? 132 ASN A N   1 
ATOM   3146 C  CA  . ASN B 2 136 ? -5.538  -24.684 15.734  1   37.81  ? 132 ASN A CA  1 
ATOM   3147 C  C   . ASN B 2 136 ? -6.826  -25.499 15.857  1   39.06  ? 132 ASN A C   1 
ATOM   3148 O  O   . ASN B 2 136 ? -7.897  -24.941 15.619  1   38.23  ? 132 ASN A O   1 
ATOM   3149 C  CB  . ASN B 2 136 ? -5.452  -23.831 14.475  1   35.77  ? 132 ASN A CB  1 
ATOM   3150 C  CG  . ASN B 2 136 ? -4.309  -22.85  14.506  1   37.36  ? 132 ASN A CG  1 
ATOM   3151 O  OD1 . ASN B 2 136 ? -3.762  -22.56  15.572  1   40.17  ? 132 ASN A OD1 1 
ATOM   3152 N  ND2 . ASN B 2 136 ? -3.942  -22.323 13.35   1   37.74  ? 132 ASN A ND2 1 
ATOM   3153 N  N   . LEU B 2 137 ? -6.712  -26.769 16.241  1   39.9   ? 133 LEU A N   1 
ATOM   3154 C  CA  . LEU B 2 137 ? -7.893  -27.653 16.401  1   39.24  ? 133 LEU A CA  1 
ATOM   3155 C  C   . LEU B 2 137 ? -8.053  -28.038 17.882  1   39.88  ? 133 LEU A C   1 
ATOM   3156 O  O   . LEU B 2 137 ? -7.214  -28.787 18.382  1   37.01  ? 133 LEU A O   1 
ATOM   3157 C  CB  . LEU B 2 137 ? -7.73   -28.84  15.456  1   37.82  ? 133 LEU A CB  1 
ATOM   3158 C  CG  . LEU B 2 137 ? -7.571  -28.505 13.972  1   37.81  ? 133 LEU A CG  1 
ATOM   3159 C  CD1 . LEU B 2 137 ? -7.525  -29.78  13.157  1   38.11  ? 133 LEU A CD1 1 
ATOM   3160 C  CD2 . LEU B 2 137 ? -8.683  -27.598 13.491  1   38.39  ? 133 LEU A CD2 1 
ATOM   3161 N  N   . LEU B 2 138 ? -9.114  -27.563 18.54   1   39.96  ? 134 LEU A N   1 
ATOM   3162 C  CA  . LEU B 2 138 ? -9.324  -27.752 19.967  1   43.06  ? 134 LEU A CA  1 
ATOM   3163 C  C   . LEU B 2 138 ? -10.327 -28.865 20.248  1   44.8   ? 134 LEU A C   1 
ATOM   3164 O  O   . LEU B 2 138 ? -11.341 -28.981 19.556  1   49.08  ? 134 LEU A O   1 
ATOM   3165 C  CB  . LEU B 2 138 ? -9.791  -26.415 20.526  1   41     ? 134 LEU A CB  1 
ATOM   3166 C  CG  . LEU B 2 138 ? -8.797  -25.275 20.281  1   43.95  ? 134 LEU A CG  1 
ATOM   3167 C  CD1 . LEU B 2 138 ? -9.367  -23.973 20.781  1   44.21  ? 134 LEU A CD1 1 
ATOM   3168 C  CD2 . LEU B 2 138 ? -7.395  -25.501 20.853  1   41.21  ? 134 LEU A CD2 1 
ATOM   3169 N  N   . ILE B 2 139 ? -10.032 -29.661 21.277  1   42.46  ? 135 ILE A N   1 
ATOM   3170 C  CA  . ILE B 2 139 ? -10.853 -30.808 21.644  1   44.5   ? 135 ILE A CA  1 
ATOM   3171 C  C   . ILE B 2 139 ? -11.326 -30.624 23.077  1   44.41  ? 135 ILE A C   1 
ATOM   3172 O  O   . ILE B 2 139 ? -10.682 -29.916 23.834  1   44.5   ? 135 ILE A O   1 
ATOM   3173 C  CB  . ILE B 2 139 ? -10.088 -32.145 21.521  1   44.73  ? 135 ILE A CB  1 
ATOM   3174 C  CG1 . ILE B 2 139 ? -8.866  -32.218 22.458  1   47.14  ? 135 ILE A CG1 1 
ATOM   3175 C  CG2 . ILE B 2 139 ? -9.687  -32.404 20.08   1   41.8   ? 135 ILE A CG2 1 
ATOM   3176 C  CD1 . ILE B 2 139 ? -8.178  -33.56  22.438  1   46.14  ? 135 ILE A CD1 1 
ATOM   3177 N  N   . ASN B 2 140 ? -12.413 -31.31  23.455  1   44.92  ? 136 ASN A N   1 
ATOM   3178 C  CA  . ASN B 2 140 ? -12.892 -31.243 24.827  1   45.05  ? 136 ASN A CA  1 
ATOM   3179 C  C   . ASN B 2 140 ? -13.004 -32.636 25.441  1   46.07  ? 136 ASN A C   1 
ATOM   3180 O  O   . ASN B 2 140 ? -12.681 -33.657 24.846  1   47.24  ? 136 ASN A O   1 
ATOM   3181 C  CB  . ASN B 2 140 ? -14.178 -30.445 24.965  1   43.57  ? 136 ASN A CB  1 
ATOM   3182 C  CG  . ASN B 2 140 ? -15.368 -31.131 24.344  1   45.85  ? 136 ASN A CG  1 
ATOM   3183 O  OD1 . ASN B 2 140 ? -15.389 -32.349 24.09   1   45.81  ? 136 ASN A OD1 1 
ATOM   3184 N  ND2 . ASN B 2 140 ? -16.397 -30.337 24.106  1   44.93  ? 136 ASN A ND2 1 
ATOM   3185 N  N   . THR B 2 141 ? -13.447 -32.649 26.688  1   49.76  ? 137 THR A N   1 
ATOM   3186 C  CA  . THR B 2 141 ? -13.611 -33.878 27.436  1   49.19  ? 137 THR A CA  1 
ATOM   3187 C  C   . THR B 2 141 ? -14.773 -34.675 26.858  1   50.91  ? 137 THR A C   1 
ATOM   3188 O  O   . THR B 2 141 ? -14.855 -35.855 27.128  1   57.69  ? 137 THR A O   1 
ATOM   3189 C  CB  . THR B 2 141 ? -13.816 -33.503 28.903  1   50.73  ? 137 THR A CB  1 
ATOM   3190 O  OG1 . THR B 2 141 ? -14.569 -32.288 28.888  1   52.11  ? 137 THR A OG1 1 
ATOM   3191 C  CG2 . THR B 2 141 ? -12.498 -33.168 29.575  1   51.57  ? 137 THR A CG2 1 
ATOM   3192 N  N   . GLU B 2 142 ? -15.633 -34.057 26.038  1   51.22  ? 138 GLU A N   1 
ATOM   3193 C  CA  . GLU B 2 142 ? -16.881 -34.68  25.622  1   54.79  ? 138 GLU A CA  1 
ATOM   3194 C  C   . GLU B 2 142 ? -16.754 -35.433 24.297  1   52.26  ? 138 GLU A C   1 
ATOM   3195 O  O   . GLU B 2 142 ? -17.562 -36.299 24.002  1   56.69  ? 138 GLU A O   1 
ATOM   3196 C  CB  . GLU B 2 142 ? -18.01  -33.651 25.545  1   58.58  ? 138 GLU A CB  1 
ATOM   3197 C  CG  . GLU B 2 142 ? -18.633 -33.334 26.901  1   64.8   ? 138 GLU A CG  1 
ATOM   3198 C  CD  . GLU B 2 142 ? -19.207 -34.516 27.667  1   71.85  ? 138 GLU A CD  1 
ATOM   3199 O  OE1 . GLU B 2 142 ? -19.974 -35.342 27.12   1   75.2   ? 138 GLU A OE1 1 
ATOM   3200 O  OE2 . GLU B 2 142 ? -18.88  -34.599 28.861  1   78.13  ? 138 GLU A OE2 1 
ATOM   3201 N  N   . GLY B 2 143 ? -15.761 -35.108 23.484  1   48.3   ? 139 GLY A N   1 
ATOM   3202 C  CA  . GLY B 2 143 ? -15.513 -35.877 22.28   1   46.38  ? 139 GLY A CA  1 
ATOM   3203 C  C   . GLY B 2 143 ? -15.573 -34.963 21.075  1   46.19  ? 139 GLY A C   1 
ATOM   3204 O  O   . GLY B 2 143 ? -15.416 -35.425 19.945  1   48.62  ? 139 GLY A O   1 
ATOM   3205 N  N   . ALA B 2 144 ? -15.795 -33.671 21.366  1   43.82  ? 140 ALA A N   1 
ATOM   3206 C  CA  . ALA B 2 144 ? -15.877 -32.621 20.362  1   41.07  ? 140 ALA A CA  1 
ATOM   3207 C  C   . ALA B 2 144 ? -14.481 -32.185 19.927  1   40.9   ? 140 ALA A C   1 
ATOM   3208 O  O   . ALA B 2 144 ? -13.565 -32.133 20.734  1   45.15  ? 140 ALA A O   1 
ATOM   3209 C  CB  . ALA B 2 144 ? -16.622 -31.457 20.968  1   37.93  ? 140 ALA A CB  1 
ATOM   3210 N  N   . ILE B 2 145 ? -14.324 -31.861 18.652  1   39.1   ? 141 ILE A N   1 
ATOM   3211 C  CA  . ILE B 2 145 ? -13.178 -31.106 18.181  1   39.36  ? 141 ILE A CA  1 
ATOM   3212 C  C   . ILE B 2 145 ? -13.71  -29.889 17.409  1   40.84  ? 141 ILE A C   1 
ATOM   3213 O  O   . ILE B 2 145 ? -14.696 -30.008 16.659  1   36.59  ? 141 ILE A O   1 
ATOM   3214 C  CB  . ILE B 2 145 ? -12.27  -31.999 17.32   1   38.13  ? 141 ILE A CB  1 
ATOM   3215 C  CG1 . ILE B 2 145 ? -10.974 -31.274 16.916  1   39.45  ? 141 ILE A CG1 1 
ATOM   3216 C  CG2 . ILE B 2 145 ? -13.021 -32.504 16.085  1   38.27  ? 141 ILE A CG2 1 
ATOM   3217 C  CD1 . ILE B 2 145 ? -9.922  -32.156 16.259  1   34.35  ? 141 ILE A CD1 1 
ATOM   3218 N  N   . LYS B 2 146 ? -13.044 -28.724 17.583  1   38.37  ? 142 LYS A N   1 
ATOM   3219 C  CA  . LYS B 2 146 ? -13.506 -27.496 16.949  1   37.98  ? 142 LYS A CA  1 
ATOM   3220 C  C   . LYS B 2 146 ? -12.375 -26.742 16.257  1   41.28  ? 142 LYS A C   1 
ATOM   3221 O  O   . LYS B 2 146 ? -11.278 -26.656 16.811  1   44.32  ? 142 LYS A O   1 
ATOM   3222 C  CB  . LYS B 2 146 ? -14.125 -26.607 18.021  1   37.81  ? 142 LYS A CB  1 
ATOM   3223 C  CG  . LYS B 2 146 ? -15.151 -27.384 18.827  1   39.38  ? 142 LYS A CG  1 
ATOM   3224 C  CD  . LYS B 2 146 ? -16.071 -26.499 19.65   1   40.1   ? 142 LYS A CD  1 
ATOM   3225 C  CE  . LYS B 2 146 ? -16.91  -27.351 20.534  1   41.34  ? 142 LYS A CE  1 
ATOM   3226 N  NZ  . LYS B 2 146 ? -17.998 -26.574 21.11   1   41.92  ? 142 LYS A NZ  1 
ATOM   3227 N  N   . LEU B 2 147 ? -12.676 -26.169 15.078  1   41.64  ? 143 LEU A N   1 
ATOM   3228 C  CA  . LEU B 2 147 ? -11.783 -25.24  14.389  1   40.06  ? 143 LEU A CA  1 
ATOM   3229 C  C   . LEU B 2 147 ? -11.591 -23.99  15.243  1   38.3   ? 143 LEU A C   1 
ATOM   3230 O  O   . LEU B 2 147 ? -12.543 -23.382 15.684  1   40.17  ? 143 LEU A O   1 
ATOM   3231 C  CB  . LEU B 2 147 ? -12.266 -24.794 13.008  1   39.33  ? 143 LEU A CB  1 
ATOM   3232 C  CG  . LEU B 2 147 ? -12.939 -25.816 12.089  1   41.41  ? 143 LEU A CG  1 
ATOM   3233 C  CD1 . LEU B 2 147 ? -12.853 -25.243 10.683  1   38.69  ? 143 LEU A CD1 1 
ATOM   3234 C  CD2 . LEU B 2 147 ? -12.404 -27.234 12.162  1   38.11  ? 143 LEU A CD2 1 
ATOM   3235 N  N   . ALA B 2 148 ? -10.347 -23.57  15.434  1   37.86  ? 144 ALA A N   1 
ATOM   3236 C  CA  . ALA B 2 148 ? -10.106 -22.357 16.19   1   38.04  ? 144 ALA A CA  1 
ATOM   3237 C  C   . ALA B 2 148 ? -9.092  -21.51  15.433  1   39.58  ? 144 ALA A C   1 
ATOM   3238 O  O   . ALA B 2 148 ? -8.648  -21.898 14.338  1   40.58  ? 144 ALA A O   1 
ATOM   3239 C  CB  . ALA B 2 148 ? -9.65   -22.7   17.594  1   36.13  ? 144 ALA A CB  1 
ATOM   3240 N  N   . ASP B 2 149 ? -8.745  -20.384 16.061  1   41.86  ? 145 ASP A N   1 
ATOM   3241 C  CA  . ASP B 2 149 ? -7.815  -19.403 15.54   1   48.51  ? 145 ASP A CA  1 
ATOM   3242 C  C   . ASP B 2 149 ? -8.23   -18.963 14.14   1   44.33  ? 145 ASP A C   1 
ATOM   3243 O  O   . ASP B 2 149 ? -7.702  -19.471 13.169  1   44.03  ? 145 ASP A O   1 
ATOM   3244 C  CB  . ASP B 2 149 ? -6.359  -19.853 15.586  1   55.19  ? 145 ASP A CB  1 
ATOM   3245 C  CG  . ASP B 2 149 ? -5.359  -18.72  15.324  1   73.54  ? 145 ASP A CG  1 
ATOM   3246 O  OD1 . ASP B 2 149 ? -5.824  -17.55  15.114  1   71.14  ? 145 ASP A OD1 1 
ATOM   3247 O  OD2 . ASP B 2 149 ? -4.117  -18.986 15.347  1   74.61  ? 145 ASP A OD2 1 
ATOM   3248 N  N   . PHE B 2 150 ? -9.137  -17.988 14.047  1   44.02  ? 146 PHE A N   1 
ATOM   3249 C  CA  . PHE B 2 150 ? -9.611  -17.5   12.759  1   46.3   ? 146 PHE A CA  1 
ATOM   3250 C  C   . PHE B 2 150 ? -8.881  -16.217 12.335  1   51.18  ? 146 PHE A C   1 
ATOM   3251 O  O   . PHE B 2 150 ? -9.404  -15.432 11.547  1   50.98  ? 146 PHE A O   1 
ATOM   3252 C  CB  . PHE B 2 150 ? -11.131 -17.313 12.824  1   42.61  ? 146 PHE A CB  1 
ATOM   3253 C  CG  . PHE B 2 150 ? -11.906 -18.585 12.517  1   39.34  ? 146 PHE A CG  1 
ATOM   3254 C  CD1 . PHE B 2 150 ? -11.896 -19.645 13.426  1   36.14  ? 146 PHE A CD1 1 
ATOM   3255 C  CD2 . PHE B 2 150 ? -12.65  -18.7   11.326  1   36.11  ? 146 PHE A CD2 1 
ATOM   3256 C  CE1 . PHE B 2 150 ? -12.625 -20.794 13.136  1   37.28  ? 146 PHE A CE1 1 
ATOM   3257 C  CE2 . PHE B 2 150 ? -13.341 -19.862 11.017  1   32.42  ? 146 PHE A CE2 1 
ATOM   3258 C  CZ  . PHE B 2 150 ? -13.35  -20.896 11.939  1   34.54  ? 146 PHE A CZ  1 
ATOM   3259 N  N   . GLY B 2 151 ? -7.65   -16.022 12.826  1   50.94  ? 147 GLY A N   1 
ATOM   3260 C  CA  . GLY B 2 151 ? -6.932  -14.768 12.65   1   48.74  ? 147 GLY A CA  1 
ATOM   3261 C  C   . GLY B 2 151 ? -6.395  -14.602 11.232  1   48.67  ? 147 GLY A C   1 
ATOM   3262 O  O   . GLY B 2 151 ? -6.249  -13.482 10.762  1   50.33  ? 147 GLY A O   1 
ATOM   3263 N  N   A LEU B 2 152 ? -6.119  -15.716 10.536  0.5 46.41  ? 148 LEU A N   1 
ATOM   3264 N  N   B LEU B 2 152 ? -6.17   -15.738 10.57   0.5 46.24  ? 148 LEU A N   1 
ATOM   3265 C  CA  A LEU B 2 152 ? -5.692  -15.67  9.142   0.5 46.63  ? 148 LEU A CA  1 
ATOM   3266 C  CA  B LEU B 2 152 ? -5.701  -15.754 9.2     0.5 46.4   ? 148 LEU A CA  1 
ATOM   3267 C  C   A LEU B 2 152 ? -6.873  -15.813 8.17    0.5 44.25  ? 148 LEU A C   1 
ATOM   3268 C  C   B LEU B 2 152 ? -6.839  -16.066 8.223   0.5 45.23  ? 148 LEU A C   1 
ATOM   3269 O  O   A LEU B 2 152 ? -6.684  -15.725 6.953   0.5 45.09  ? 148 LEU A O   1 
ATOM   3270 O  O   B LEU B 2 152 ? -6.583  -16.331 7.048   0.5 49.41  ? 148 LEU A O   1 
ATOM   3271 C  CB  A LEU B 2 152 ? -4.594  -16.698 8.854   0.5 46.4   ? 148 LEU A CB  1 
ATOM   3272 C  CB  B LEU B 2 152 ? -4.562  -16.771 9.152   0.5 44.63  ? 148 LEU A CB  1 
ATOM   3273 C  CG  A LEU B 2 152 ? -3.858  -16.551 7.511   0.5 46.37  ? 148 LEU A CG  1 
ATOM   3274 C  CG  B LEU B 2 152 ? -3.275  -16.316 9.848   0.5 43.79  ? 148 LEU A CG  1 
ATOM   3275 C  CD1 A LEU B 2 152 ? -3.293  -15.134 7.296   0.5 46.01  ? 148 LEU A CD1 1 
ATOM   3276 C  CD1 B LEU B 2 152 ? -2.184  -17.316 9.573   0.5 45.4   ? 148 LEU A CD1 1 
ATOM   3277 C  CD2 A LEU B 2 152 ? -2.764  -17.615 7.353   0.5 42.06  ? 148 LEU A CD2 1 
ATOM   3278 C  CD2 B LEU B 2 152 ? -2.853  -14.94  9.376   0.5 42.72  ? 148 LEU A CD2 1 
ATOM   3279 N  N   . ALA B 2 153 ? -8.09   -15.989 8.699   1   41.22  ? 149 ALA A N   1 
ATOM   3280 C  CA  . ALA B 2 153 ? -9.244  -16.349 7.888   1   39.38  ? 149 ALA A CA  1 
ATOM   3281 C  C   . ALA B 2 153 ? -9.696  -15.172 7.042   1   41.52  ? 149 ALA A C   1 
ATOM   3282 O  O   . ALA B 2 153 ? -9.218  -14.048 7.232   1   45.8   ? 149 ALA A O   1 
ATOM   3283 C  CB  . ALA B 2 153 ? -10.354 -16.839 8.766   1   38.07  ? 149 ALA A CB  1 
ATOM   3284 N  N   . ARG B 2 154 ? -10.632 -15.426 6.117   1   39.76  ? 150 ARG A N   1 
ATOM   3285 C  CA  . ARG B 2 154 ? -10.932 -14.398 5.124   1   42.33  ? 150 ARG A CA  1 
ATOM   3286 C  C   . ARG B 2 154 ? -12.329 -14.58  4.522   1   42.37  ? 150 ARG A C   1 
ATOM   3287 O  O   . ARG B 2 154 ? -12.691 -15.672 4.061   1   43.72  ? 150 ARG A O   1 
ATOM   3288 C  CB  . ARG B 2 154 ? -9.772  -14.45  4.122   1   40.28  ? 150 ARG A CB  1 
ATOM   3289 C  CG  . ARG B 2 154 ? -10.015 -13.898 2.729   1   42.41  ? 150 ARG A CG  1 
ATOM   3290 C  CD  . ARG B 2 154 ? -10.077 -12.388 2.615   1   45.85  ? 150 ARG A CD  1 
ATOM   3291 N  NE  . ARG B 2 154 ? -8.892  -11.815 1.965   1   46.62  ? 150 ARG A NE  1 
ATOM   3292 C  CZ  . ARG B 2 154 ? -8.86   -10.578 1.446   1   49.06  ? 150 ARG A CZ  1 
ATOM   3293 N  NH1 . ARG B 2 154 ? -7.707  -10.027 1.116   1   48.49  ? 150 ARG A NH1 1 
ATOM   3294 N  NH2 . ARG B 2 154 ? -9.968  -9.858  1.316   1   50.93  ? 150 ARG A NH2 1 
ATOM   3295 N  N   . ALA B 2 155 ? -13.108 -13.493 4.499   1   40.23  ? 151 ALA A N   1 
ATOM   3296 C  CA  . ALA B 2 155 ? -14.418 -13.544 3.849   1   39.62  ? 151 ALA A CA  1 
ATOM   3297 C  C   . ALA B 2 155 ? -14.27  -13.494 2.33    1   41.08  ? 151 ALA A C   1 
ATOM   3298 O  O   . ALA B 2 155 ? -13.753 -12.509 1.797   1   41.77  ? 151 ALA A O   1 
ATOM   3299 C  CB  . ALA B 2 155 ? -15.279 -12.395 4.307   1   39.79  ? 151 ALA A CB  1 
ATOM   3300 N  N   . PHE B 2 156 ? -14.756 -14.534 1.631   1   40.71  ? 152 PHE A N   1 
ATOM   3301 C  CA  . PHE B 2 156 ? -14.589 -14.546 0.187   1   40.12  ? 152 PHE A CA  1 
ATOM   3302 C  C   . PHE B 2 156 ? -15.867 -14.121 -0.524  1   44.72  ? 152 PHE A C   1 
ATOM   3303 O  O   . PHE B 2 156 ? -16.96  -14.071 0.078   1   46.99  ? 152 PHE A O   1 
ATOM   3304 C  CB  . PHE B 2 156 ? -14.029 -15.848 -0.374  1   39.18  ? 152 PHE A CB  1 
ATOM   3305 C  CG  . PHE B 2 156 ? -14.832 -17.134 -0.213  1   41.06  ? 152 PHE A CG  1 
ATOM   3306 C  CD1 . PHE B 2 156 ? -14.735 -17.892 0.958   1   39.34  ? 152 PHE A CD1 1 
ATOM   3307 C  CD2 . PHE B 2 156 ? -15.582 -17.646 -1.284  1   38.82  ? 152 PHE A CD2 1 
ATOM   3308 C  CE1 . PHE B 2 156 ? -15.436 -19.092 1.085   1   37.61  ? 152 PHE A CE1 1 
ATOM   3309 C  CE2 . PHE B 2 156 ? -16.242 -18.864 -1.172  1   36.64  ? 152 PHE A CE2 1 
ATOM   3310 C  CZ  . PHE B 2 156 ? -16.186 -19.578 0.021   1   36.69  ? 152 PHE A CZ  1 
ATOM   3311 N  N   . GLY B 2 157 ? -15.672 -13.789 -1.817  1   43.53  ? 153 GLY A N   1 
ATOM   3312 C  CA  . GLY B 2 157 ? -16.74  -13.601 -2.783  1   42.26  ? 153 GLY A CA  1 
ATOM   3313 C  C   . GLY B 2 157 ? -16.715 -14.683 -3.864  1   43.3   ? 153 GLY A C   1 
ATOM   3314 O  O   . GLY B 2 157 ? -15.75  -15.443 -3.964  1   41.74  ? 153 GLY A O   1 
ATOM   3315 N  N   . VAL B 2 158 ? -17.762 -14.708 -4.708  1   43.21  ? 154 VAL A N   1 
ATOM   3316 C  CA  . VAL B 2 158 ? -17.929 -15.769 -5.684  1   41.38  ? 154 VAL A CA  1 
ATOM   3317 C  C   . VAL B 2 158 ? -18.052 -15.118 -7.048  1   41.85  ? 154 VAL A C   1 
ATOM   3318 O  O   . VAL B 2 158 ? -18.795 -14.146 -7.165  1   42.17  ? 154 VAL A O   1 
ATOM   3319 C  CB  . VAL B 2 158 ? -19.132 -16.661 -5.322  1   43.42  ? 154 VAL A CB  1 
ATOM   3320 C  CG1 . VAL B 2 158 ? -19.391 -17.708 -6.41   1   42.26  ? 154 VAL A CG1 1 
ATOM   3321 C  CG2 . VAL B 2 158 ? -18.956 -17.292 -3.92   1   38.79  ? 154 VAL A CG2 1 
ATOM   3322 N  N   . PRO B 2 159 ? -17.186 -15.478 -8.041  1   41.27  ? 155 PRO A N   1 
ATOM   3323 C  CA  . PRO B 2 159 ? -15.975 -16.272 -7.812  1   40.13  ? 155 PRO A CA  1 
ATOM   3324 C  C   . PRO B 2 159 ? -14.909 -15.546 -6.981  1   41.71  ? 155 PRO A C   1 
ATOM   3325 O  O   . PRO B 2 159 ? -15.048 -14.366 -6.655  1   40.82  ? 155 PRO A O   1 
ATOM   3326 C  CB  . PRO B 2 159 ? -15.476 -16.532 -9.241  1   39.68  ? 155 PRO A CB  1 
ATOM   3327 C  CG  . PRO B 2 159 ? -15.934 -15.352 -10.033 1   39.57  ? 155 PRO A CG  1 
ATOM   3328 C  CD  . PRO B 2 159 ? -17.292 -15.056 -9.45   1   43     ? 155 PRO A CD  1 
ATOM   3329 N  N   . VAL B 2 160 ? -13.875 -16.285 -6.571  1   41.01  ? 156 VAL A N   1 
ATOM   3330 C  CA  . VAL B 2 160 ? -12.852 -15.691 -5.655  1   38.29  ? 156 VAL A CA  1 
ATOM   3331 C  C   . VAL B 2 160 ? -11.936 -14.729 -6.424  1   39.37  ? 156 VAL A C   1 
ATOM   3332 O  O   . VAL B 2 160 ? -11.806 -14.883 -7.657  1   36.97  ? 156 VAL A O   1 
ATOM   3333 C  CB  . VAL B 2 160 ? -12.03  -16.792 -4.957  1   36.72  ? 156 VAL A CB  1 
ATOM   3334 C  CG1 . VAL B 2 160 ? -12.887 -17.624 -4.012  1   34.67  ? 156 VAL A CG1 1 
ATOM   3335 C  CG2 . VAL B 2 160 ? -11.31  -17.686 -5.96   1   34.59  ? 156 VAL A CG2 1 
ATOM   3336 N  N   . ARG B 2 161 ? -11.33  -13.782 -5.722  1   42.65  ? 157 ARG A N   1 
ATOM   3337 C  CA  . ARG B 2 161 ? -10.358 -12.856 -6.346  1   47.93  ? 157 ARG A CA  1 
ATOM   3338 C  C   . ARG B 2 161 ? -8.977  -13.158 -5.745  1   47.55  ? 157 ARG A C   1 
ATOM   3339 O  O   . ARG B 2 161 ? -8.871  -14.12  -4.972  1   43.61  ? 157 ARG A O   1 
ATOM   3340 C  CB  . ARG B 2 161 ? -10.819 -11.41  -6.141  1   49.31  ? 157 ARG A CB  1 
ATOM   3341 C  CG  . ARG B 2 161 ? -10.789 -10.848 -4.73   1   51.57  ? 157 ARG A CG  1 
ATOM   3342 C  CD  . ARG B 2 161 ? -9.944  -9.594  -4.657  1   60.72  ? 157 ARG A CD  1 
ATOM   3343 N  NE  . ARG B 2 161 ? -10.735 -8.454  -4.187  1   68.64  ? 157 ARG A NE  1 
ATOM   3344 C  CZ  . ARG B 2 161 ? -11.127 -8.284  -2.935  1   66.75  ? 157 ARG A CZ  1 
ATOM   3345 N  NH1 . ARG B 2 161 ? -12.397 -8.046  -2.672  1   66.23  ? 157 ARG A NH1 1 
ATOM   3346 N  NH2 . ARG B 2 161 ? -10.249 -8.35   -1.953  1   62.12  ? 157 ARG A NH2 1 
ATOM   3347 N  N   . THR B 2 162 ? -7.958  -12.388 -6.125  1   49.77  ? 158 THR A N   1 
ATOM   3348 C  CA  . THR B 2 162 ? -6.597  -12.676 -5.624  1   49.01  ? 158 THR A CA  1 
ATOM   3349 C  C   . THR B 2 162 ? -6.48   -12.245 -4.178  1   46.97  ? 158 THR A C   1 
ATOM   3350 O  O   . THR B 2 162 ? -6.565  -11.025 -3.921  1   46.97  ? 158 THR A O   1 
ATOM   3351 C  CB  . THR B 2 162 ? -5.564  -11.989 -6.515  1   51.63  ? 158 THR A CB  1 
ATOM   3352 O  OG1 . THR B 2 162 ? -5.777  -12.547 -7.808  1   56.44  ? 158 THR A OG1 1 
ATOM   3353 C  CG2 . THR B 2 162 ? -4.139  -12.253 -6.063  1   44.51  ? 158 THR A CG2 1 
ATOM   3354 N  N   . TYR B 2 163 ? -6.317  -13.2   -3.259  1   46.04  ? 159 TYR A N   1 
ATOM   3355 C  CA  . TYR B 2 163 ? -6.105  -12.881 -1.86   1   47.71  ? 159 TYR A CA  1 
ATOM   3356 C  C   . TYR B 2 163 ? -4.619  -13.036 -1.498  1   46.99  ? 159 TYR A C   1 
ATOM   3357 O  O   . TYR B 2 163 ? -3.742  -13.148 -2.363  1   41.84  ? 159 TYR A O   1 
ATOM   3358 C  CB  . TYR B 2 163 ? -6.992  -13.82  -1.028  1   50.08  ? 159 TYR A CB  1 
ATOM   3359 C  CG  . TYR B 2 163 ? -8.464  -13.821 -1.414  1   50.99  ? 159 TYR A CG  1 
ATOM   3360 C  CD1 . TYR B 2 163 ? -9.162  -12.626 -1.602  1   49.57  ? 159 TYR A CD1 1 
ATOM   3361 C  CD2 . TYR B 2 163 ? -9.147  -15.022 -1.589  1   48.41  ? 159 TYR A CD2 1 
ATOM   3362 C  CE1 . TYR B 2 163 ? -10.487 -12.629 -1.993  1   50.74  ? 159 TYR A CE1 1 
ATOM   3363 C  CE2 . TYR B 2 163 ? -10.479 -15.029 -1.977  1   48.6   ? 159 TYR A CE2 1 
ATOM   3364 C  CZ  . TYR B 2 163 ? -11.144 -13.833 -2.185  1   49.68  ? 159 TYR A CZ  1 
ATOM   3365 O  OH  . TYR B 2 163 ? -12.445 -13.82  -2.581  1   54.87  ? 159 TYR A OH  1 
HETATM 3366 N  N   . TPO B 2 164 ? -4.327  -12.991 -0.204  1   45.47  ? 160 TPO A N   1 
HETATM 3367 C  CA  . TPO B 2 164 ? -2.919  -13.02  0.262   1   47.71  ? 160 TPO A CA  1 
HETATM 3368 C  CB  . TPO B 2 164 ? -2.868  -12.686 1.759   1   47.81  ? 160 TPO A CB  1 
HETATM 3369 C  CG2 . TPO B 2 164 ? -1.47   -12.395 2.247   1   41     ? 160 TPO A CG2 1 
HETATM 3370 O  OG1 . TPO B 2 164 ? -3.673  -11.481 1.971   1   49.93  ? 160 TPO A OG1 1 
HETATM 3371 P  P   . TPO B 2 164 ? -5.047  -11.515 2.801   1   47.68  ? 160 TPO A P   1 
HETATM 3372 O  O1P . TPO B 2 164 ? -5.999  -12.33  1.97    1   43.97  ? 160 TPO A O1P 1 
HETATM 3373 O  O2P . TPO B 2 164 ? -5.476  -10.081 2.945   1   44.56  ? 160 TPO A O2P 1 
HETATM 3374 O  O3P . TPO B 2 164 ? -4.727  -12.163 4.12    1   46.2   ? 160 TPO A O3P 1 
HETATM 3375 C  C   . TPO B 2 164 ? -2.235  -14.343 -0.092  1   47.62  ? 160 TPO A C   1 
HETATM 3376 O  O   . TPO B 2 164 ? -2.887  -15.382 0.013   1   44.38  ? 160 TPO A O   1 
ATOM   3377 N  N   . HIS B 2 165 ? -0.953  -14.283 -0.461  1   51.04  ? 161 HIS A N   1 
ATOM   3378 C  CA  . HIS B 2 165 ? -0.175  -15.487 -0.845  1   55.59  ? 161 HIS A CA  1 
ATOM   3379 C  C   . HIS B 2 165 ? 0.605   -16.015 0.358   1   58.83  ? 161 HIS A C   1 
ATOM   3380 O  O   . HIS B 2 165 ? 0.665   -15.339 1.396   1   68     ? 161 HIS A O   1 
ATOM   3381 C  CB  . HIS B 2 165 ? 0.76    -15.15  -2.01   1   60.33  ? 161 HIS A CB  1 
ATOM   3382 C  CG  . HIS B 2 165 ? 1.713   -16.226 -2.43   1   80.81  ? 161 HIS A CG  1 
ATOM   3383 N  ND1 . HIS B 2 165 ? 3.074   -16.026 -2.505  1   88.76  ? 161 HIS A ND1 1 
ATOM   3384 C  CD2 . HIS B 2 165 ? 1.519   -17.502 -2.773  1   77.18  ? 161 HIS A CD2 1 
ATOM   3385 C  CE1 . HIS B 2 165 ? 3.659   -17.147 -2.898  1   82.42  ? 161 HIS A CE1 1 
ATOM   3386 N  NE2 . HIS B 2 165 ? 2.733   -18.059 -3.057  1   81.6   ? 161 HIS A NE2 1 
ATOM   3387 N  N   . GLU B 2 166 ? 1.19    -17.202 0.21    1   65.89  ? 162 GLU A N   1 
ATOM   3388 C  CA  . GLU B 2 166 ? 1.974   -17.823 1.305   1   83.78  ? 162 GLU A CA  1 
ATOM   3389 C  C   . GLU B 2 166 ? 1.071   -17.783 2.531   1   82.01  ? 162 GLU A C   1 
ATOM   3390 O  O   . GLU B 2 166 ? 1.489   -17.251 3.574   1   71.1   ? 162 GLU A O   1 
ATOM   3391 C  CB  . GLU B 2 166 ? 3.328   -17.157 1.541   1   97.64  ? 162 GLU A CB  1 
ATOM   3392 C  CG  . GLU B 2 166 ? 4.379   -17.529 0.501   1   97.76  ? 162 GLU A CG  1 
ATOM   3393 C  CD  . GLU B 2 166 ? 5.437   -16.464 0.281   1   90.46  ? 162 GLU A CD  1 
ATOM   3394 O  OE1 . GLU B 2 166 ? 6.115   -16.093 1.259   1   88.61  ? 162 GLU A OE1 1 
ATOM   3395 O  OE2 . GLU B 2 166 ? 5.586   -16     -0.865  1   89.65  ? 162 GLU A OE2 1 
ATOM   3396 N  N   . VAL B 2 167 ? -0.148  -18.271 2.361   1   63.85  ? 163 VAL A N   1 
ATOM   3397 C  CA  . VAL B 2 167 ? -1.069  -18.378 3.512   1   56.72  ? 163 VAL A CA  1 
ATOM   3398 C  C   . VAL B 2 167 ? -1.019  -19.856 3.905   1   49.84  ? 163 VAL A C   1 
ATOM   3399 O  O   . VAL B 2 167 ? -0.565  -20.647 3.063   1   48.29  ? 163 VAL A O   1 
ATOM   3400 C  CB  . VAL B 2 167 ? -2.45   -17.885 3.047   1   56.6   ? 163 VAL A CB  1 
ATOM   3401 C  CG1 . VAL B 2 167 ? -3.198  -18.908 2.205   1   44.93  ? 163 VAL A CG1 1 
ATOM   3402 C  CG2 . VAL B 2 167 ? -3.297  -17.373 4.202   1   67.57  ? 163 VAL A CG2 1 
ATOM   3403 N  N   . VAL B 2 168 ? -1.397  -20.19  5.133   1   44.89  ? 164 VAL A N   1 
ATOM   3404 C  CA  . VAL B 2 168 ? -1.403  -21.598 5.636   1   43.49  ? 164 VAL A CA  1 
ATOM   3405 C  C   . VAL B 2 168 ? 0.015   -22.005 6.058   1   45.85  ? 164 VAL A C   1 
ATOM   3406 O  O   . VAL B 2 168 ? 0.939   -21.839 5.255   1   44.83  ? 164 VAL A O   1 
ATOM   3407 C  CB  . VAL B 2 168 ? -2.027  -22.67  4.71    1   39.93  ? 164 VAL A CB  1 
ATOM   3408 C  CG1 . VAL B 2 168 ? -2.221  -23.989 5.44    1   36.74  ? 164 VAL A CG1 1 
ATOM   3409 C  CG2 . VAL B 2 168 ? -3.344  -22.221 4.091   1   35.23  ? 164 VAL A CG2 1 
ATOM   3410 N  N   . THR B 2 169 ? 0.177   -22.477 7.292   1   45.69  ? 165 THR A N   1 
ATOM   3411 C  CA  . THR B 2 169 ? 1.456   -23.03  7.728   1   48     ? 165 THR A CA  1 
ATOM   3412 C  C   . THR B 2 169 ? 1.936   -24.052 6.688   1   48.65  ? 165 THR A C   1 
ATOM   3413 O  O   . THR B 2 169 ? 1.154   -24.84  6.14    1   45.71  ? 165 THR A O   1 
ATOM   3414 C  CB  . THR B 2 169 ? 1.292   -23.665 9.112   1   48.27  ? 165 THR A CB  1 
ATOM   3415 O  OG1 . THR B 2 169 ? 0.791   -22.675 10.012  1   48.72  ? 165 THR A OG1 1 
ATOM   3416 C  CG2 . THR B 2 169 ? 2.569   -24.277 9.658   1   44.92  ? 165 THR A CG2 1 
ATOM   3417 N  N   . LEU B 2 170 ? 3.248   -24.03  6.443   1   44.09  ? 166 LEU A N   1 
ATOM   3418 C  CA  . LEU B 2 170 ? 3.834   -24.598 5.247   1   42.4   ? 166 LEU A CA  1 
ATOM   3419 C  C   . LEU B 2 170 ? 3.517   -26.085 5.15    1   43.08  ? 166 LEU A C   1 
ATOM   3420 O  O   . LEU B 2 170 ? 3.163   -26.55  4.073   1   41.28  ? 166 LEU A O   1 
ATOM   3421 C  CB  . LEU B 2 170 ? 5.339   -24.337 5.297   1   45.21  ? 166 LEU A CB  1 
ATOM   3422 C  CG  . LEU B 2 170 ? 6.195   -24.951 4.178   1   44.82  ? 166 LEU A CG  1 
ATOM   3423 C  CD1 . LEU B 2 170 ? 5.897   -24.272 2.838   1   44.75  ? 166 LEU A CD1 1 
ATOM   3424 C  CD2 . LEU B 2 170 ? 7.683   -24.894 4.522   1   38.67  ? 166 LEU A CD2 1 
ATOM   3425 N  N   . TRP B 2 171 ? 3.673   -26.838 6.254   1   42.61  ? 167 TRP A N   1 
ATOM   3426 C  CA  . TRP B 2 171 ? 3.411   -28.274 6.163   1   41.06  ? 167 TRP A CA  1 
ATOM   3427 C  C   . TRP B 2 171 ? 2.001   -28.571 5.657   1   41.03  ? 167 TRP A C   1 
ATOM   3428 O  O   . TRP B 2 171 ? 1.732   -29.685 5.227   1   45.03  ? 167 TRP A O   1 
ATOM   3429 C  CB  . TRP B 2 171 ? 3.621   -28.993 7.496   1   37.87  ? 167 TRP A CB  1 
ATOM   3430 C  CG  . TRP B 2 171 ? 5.039   -28.973 7.985   1   40.17  ? 167 TRP A CG  1 
ATOM   3431 C  CD1 . TRP B 2 171 ? 6.146   -28.507 7.322   1   40.84  ? 167 TRP A CD1 1 
ATOM   3432 C  CD2 . TRP B 2 171 ? 5.497   -29.449 9.267   1   39.13  ? 167 TRP A CD2 1 
ATOM   3433 N  NE1 . TRP B 2 171 ? 7.254   -28.633 8.115   1   40.02  ? 167 TRP A NE1 1 
ATOM   3434 C  CE2 . TRP B 2 171 ? 6.897   -29.21  9.305   1   40.67  ? 167 TRP A CE2 1 
ATOM   3435 C  CE3 . TRP B 2 171 ? 4.864   -30.036 10.37   1   37.29  ? 167 TRP A CE3 1 
ATOM   3436 C  CZ2 . TRP B 2 171 ? 7.681   -29.564 10.403  1   41.67  ? 167 TRP A CZ2 1 
ATOM   3437 C  CZ3 . TRP B 2 171 ? 5.64    -30.392 11.449  1   40.19  ? 167 TRP A CZ3 1 
ATOM   3438 C  CH2 . TRP B 2 171 ? 7.033   -30.168 11.462  1   41.49  ? 167 TRP A CH2 1 
ATOM   3439 N  N   . TYR B 2 172 ? 1.095   -27.595 5.751   1   40.48  ? 168 TYR A N   1 
ATOM   3440 C  CA  . TYR B 2 172 ? -0.325  -27.824 5.494   1   40.94  ? 168 TYR A CA  1 
ATOM   3441 C  C   . TYR B 2 172 ? -0.753  -27.055 4.239   1   40.97  ? 168 TYR A C   1 
ATOM   3442 O  O   . TYR B 2 172 ? -1.941  -26.987 3.927   1   40.25  ? 168 TYR A O   1 
ATOM   3443 C  CB  . TYR B 2 172 ? -1.161  -27.584 6.767   1   35.85  ? 168 TYR A CB  1 
ATOM   3444 C  CG  . TYR B 2 172 ? -0.664  -28.372 7.978   1   34.43  ? 168 TYR A CG  1 
ATOM   3445 C  CD1 . TYR B 2 172 ? -1.114  -29.669 8.222   1   32.03  ? 168 TYR A CD1 1 
ATOM   3446 C  CD2 . TYR B 2 172 ? 0.309   -27.852 8.845   1   36.44  ? 168 TYR A CD2 1 
ATOM   3447 C  CE1 . TYR B 2 172 ? -0.641  -30.429 9.287   1   32.4   ? 168 TYR A CE1 1 
ATOM   3448 C  CE2 . TYR B 2 172 ? 0.769   -28.594 9.931   1   35.77  ? 168 TYR A CE2 1 
ATOM   3449 C  CZ  . TYR B 2 172 ? 0.294   -29.883 10.154  1   34.77  ? 168 TYR A CZ  1 
ATOM   3450 O  OH  . TYR B 2 172 ? 0.787   -30.605 11.202  1   34.13  ? 168 TYR A OH  1 
ATOM   3451 N  N   . ARG B 2 173 ? 0.227   -26.503 3.501   1   40.89  ? 169 ARG A N   1 
ATOM   3452 C  CA  . ARG B 2 173 ? -0.07   -25.583 2.411   1   39.96  ? 169 ARG A CA  1 
ATOM   3453 C  C   . ARG B 2 173 ? -0.247  -26.362 1.107   1   41.7   ? 169 ARG A C   1 
ATOM   3454 O  O   . ARG B 2 173 ? 0.583   -27.196 0.761   1   41.41  ? 169 ARG A O   1 
ATOM   3455 C  CB  . ARG B 2 173 ? 1.005   -24.497 2.317   1   38.74  ? 169 ARG A CB  1 
ATOM   3456 C  CG  . ARG B 2 173 ? 0.744   -23.47  1.223   1   39.97  ? 169 ARG A CG  1 
ATOM   3457 C  CD  . ARG B 2 173 ? 1.772   -22.356 1.124   1   38.18  ? 169 ARG A CD  1 
ATOM   3458 N  NE  . ARG B 2 173 ? 2.097   -21.906 2.483   1   40.84  ? 169 ARG A NE  1 
ATOM   3459 C  CZ  . ARG B 2 173 ? 3.225   -21.311 2.889   1   40.54  ? 169 ARG A CZ  1 
ATOM   3460 N  NH1 . ARG B 2 173 ? 4.196   -20.996 2.061   1   39.57  ? 169 ARG A NH1 1 
ATOM   3461 N  NH2 . ARG B 2 173 ? 3.385   -21.077 4.165   1   42.51  ? 169 ARG A NH2 1 
ATOM   3462 N  N   . ALA B 2 174 ? -1.342  -26.057 0.399   1   40.45  ? 170 ALA A N   1 
ATOM   3463 C  CA  . ALA B 2 174 ? -1.748  -26.704 -0.837  1   36.54  ? 170 ALA A CA  1 
ATOM   3464 C  C   . ALA B 2 174 ? -0.841  -26.315 -2.009  1   39.09  ? 170 ALA A C   1 
ATOM   3465 O  O   . ALA B 2 174 ? -0.289  -25.207 -2.089  1   39.07  ? 170 ALA A O   1 
ATOM   3466 C  CB  . ALA B 2 174 ? -3.166  -26.301 -1.132  1   34.03  ? 170 ALA A CB  1 
ATOM   3467 N  N   . PRO B 2 175 ? -0.688  -27.22  -2.997  1   36.94  ? 171 PRO A N   1 
ATOM   3468 C  CA  . PRO B 2 175 ? 0.291   -27.017 -4.053  1   37.79  ? 171 PRO A CA  1 
ATOM   3469 C  C   . PRO B 2 175 ? -0.021  -25.794 -4.913  1   38.88  ? 171 PRO A C   1 
ATOM   3470 O  O   . PRO B 2 175 ? 0.913   -25.137 -5.417  1   39.89  ? 171 PRO A O   1 
ATOM   3471 C  CB  . PRO B 2 175 ? 0.295   -28.397 -4.782  1   35.28  ? 171 PRO A CB  1 
ATOM   3472 C  CG  . PRO B 2 175 ? -1.071  -28.929 -4.526  1   34.9   ? 171 PRO A CG  1 
ATOM   3473 C  CD  . PRO B 2 175 ? -1.365  -28.515 -3.096  1   35.12  ? 171 PRO A CD  1 
ATOM   3474 N  N   . GLU B 2 176 ? -1.32   -25.472 -5.042  1   35.24  ? 172 GLU A N   1 
ATOM   3475 C  CA  . GLU B 2 176 ? -1.676  -24.343 -5.878  1   37.23  ? 172 GLU A CA  1 
ATOM   3476 C  C   . GLU B 2 176 ? -1.131  -23.046 -5.276  1   39.77  ? 172 GLU A C   1 
ATOM   3477 O  O   . GLU B 2 176 ? -0.839  -22.115 -6.023  1   41.46  ? 172 GLU A O   1 
ATOM   3478 C  CB  . GLU B 2 176 ? -3.156  -24.286 -6.256  1   42.67  ? 172 GLU A CB  1 
ATOM   3479 C  CG  . GLU B 2 176 ? -4.141  -24.212 -5.094  1   40.96  ? 172 GLU A CG  1 
ATOM   3480 C  CD  . GLU B 2 176 ? -4.599  -25.54  -4.489  1   42.3   ? 172 GLU A CD  1 
ATOM   3481 O  OE1 . GLU B 2 176 ? -5.723  -25.592 -3.938  1   39.62  ? 172 GLU A OE1 1 
ATOM   3482 O  OE2 . GLU B 2 176 ? -3.799  -26.511 -4.504  1   43.12  ? 172 GLU A OE2 1 
ATOM   3483 N  N   . ILE B 2 177 ? -0.966  -22.978 -3.938  1   38.49  ? 173 ILE A N   1 
ATOM   3484 C  CA  . ILE B 2 177 ? -0.392  -21.791 -3.317  1   38.07  ? 173 ILE A CA  1 
ATOM   3485 C  C   . ILE B 2 177 ? 1.12    -21.847 -3.52   1   42.11  ? 173 ILE A C   1 
ATOM   3486 O  O   . ILE B 2 177 ? 1.775   -20.855 -3.835  1   42.5   ? 173 ILE A O   1 
ATOM   3487 C  CB  . ILE B 2 177 ? -0.739  -21.716 -1.818  1   39.96  ? 173 ILE A CB  1 
ATOM   3488 C  CG1 . ILE B 2 177 ? -2.196  -22.151 -1.529  1   42.33  ? 173 ILE A CG1 1 
ATOM   3489 C  CG2 . ILE B 2 177 ? -0.445  -20.329 -1.263  1   37.56  ? 173 ILE A CG2 1 
ATOM   3490 C  CD1 . ILE B 2 177 ? -2.713  -21.784 -0.154  1   40.39  ? 173 ILE A CD1 1 
ATOM   3491 N  N   . LEU B 2 178 ? 1.678   -23.039 -3.336  1   40.39  ? 174 LEU A N   1 
ATOM   3492 C  CA  . LEU B 2 178 ? 3.107   -23.199 -3.509  1   40.92  ? 174 LEU A CA  1 
ATOM   3493 C  C   . LEU B 2 178 ? 3.474   -22.8   -4.938  1   41.28  ? 174 LEU A C   1 
ATOM   3494 O  O   . LEU B 2 178 ? 4.553   -22.228 -5.15   1   41.04  ? 174 LEU A O   1 
ATOM   3495 C  CB  . LEU B 2 178 ? 3.556   -24.601 -3.083  1   39.22  ? 174 LEU A CB  1 
ATOM   3496 C  CG  . LEU B 2 178 ? 3.525   -24.835 -1.565  1   36.69  ? 174 LEU A CG  1 
ATOM   3497 C  CD1 . LEU B 2 178 ? 3.404   -26.29  -1.204  1   36.12  ? 174 LEU A CD1 1 
ATOM   3498 C  CD2 . LEU B 2 178 ? 4.788   -24.257 -0.952  1   36.29  ? 174 LEU A CD2 1 
ATOM   3499 N  N   . LEU B 2 179 ? 2.556   -23.009 -5.9    1   37.68  ? 175 LEU A N   1 
ATOM   3500 C  CA  . LEU B 2 179 ? 2.895   -22.665 -7.282  1   40.73  ? 175 LEU A CA  1 
ATOM   3501 C  C   . LEU B 2 179 ? 2.499   -21.226 -7.64   1   45.22  ? 175 LEU A C   1 
ATOM   3502 O  O   . LEU B 2 179 ? 2.533   -20.84  -8.813  1   47.32  ? 175 LEU A O   1 
ATOM   3503 C  CB  . LEU B 2 179 ? 2.342   -23.69  -8.264  1   37.16  ? 175 LEU A CB  1 
ATOM   3504 C  CG  . LEU B 2 179 ? 2.965   -25.085 -8.173  1   35.98  ? 175 LEU A CG  1 
ATOM   3505 C  CD1 . LEU B 2 179 ? 2.17    -26.029 -9.057  1   35.34  ? 175 LEU A CD1 1 
ATOM   3506 C  CD2 . LEU B 2 179 ? 4.434   -25.047 -8.556  1   36.51  ? 175 LEU A CD2 1 
ATOM   3507 N  N   . GLY B 2 180 ? 2.153   -20.427 -6.618  1   44.5   ? 176 GLY A N   1 
ATOM   3508 C  CA  . GLY B 2 180 ? 1.86    -19.017 -6.797  1   45.48  ? 176 GLY A CA  1 
ATOM   3509 C  C   . GLY B 2 180 ? 0.644   -18.76  -7.69   1   47.41  ? 176 GLY A C   1 
ATOM   3510 O  O   . GLY B 2 180 ? 0.597   -17.733 -8.376  1   46.58  ? 176 GLY A O   1 
ATOM   3511 N  N   . CYS B 2 181 ? -0.317  -19.701 -7.703  1   47.15  ? 177 CYS A N   1 
ATOM   3512 C  CA  . CYS B 2 181 ? -1.51   -19.553 -8.532  1   48.5   ? 177 CYS A CA  1 
ATOM   3513 C  C   . CYS B 2 181 ? -2.167  -18.197 -8.223  1   46.92  ? 177 CYS A C   1 
ATOM   3514 O  O   . CYS B 2 181 ? -2.102  -17.689 -7.091  1   41.34  ? 177 CYS A O   1 
ATOM   3515 C  CB  . CYS B 2 181 ? -2.384  -20.811 -8.483  1   55.2   ? 177 CYS A CB  1 
ATOM   3516 S  SG  . CYS B 2 181 ? -1.929  -22.156 -9.648  1   64.86  ? 177 CYS A SG  1 
ATOM   3517 N  N   . LYS B 2 182 ? -2.72   -17.554 -9.264  1   44.13  ? 178 LYS A N   1 
ATOM   3518 C  CA  . LYS B 2 182 ? -3.406  -16.279 -9.08   1   45.51  ? 178 LYS A CA  1 
ATOM   3519 C  C   . LYS B 2 182 ? -4.594  -16.39  -8.107  1   41.91  ? 178 LYS A C   1 
ATOM   3520 O  O   . LYS B 2 182 ? -4.905  -15.459 -7.36   1   41.06  ? 178 LYS A O   1 
ATOM   3521 C  CB  . LYS B 2 182 ? -3.781  -15.817 -10.486 1   50.78  ? 178 LYS A CB  1 
ATOM   3522 C  CG  . LYS B 2 182 ? -4.412  -14.442 -10.589 1   60.86  ? 178 LYS A CG  1 
ATOM   3523 C  CD  . LYS B 2 182 ? -5.016  -14.09  -11.951 1   66.05  ? 178 LYS A CD  1 
ATOM   3524 C  CE  . LYS B 2 182 ? -5.432  -12.633 -11.969 1   74.25  ? 178 LYS A CE  1 
ATOM   3525 N  NZ  . LYS B 2 182 ? -6.067  -12.169 -13.21  1   77.65  ? 178 LYS A NZ  1 
ATOM   3526 N  N   . TYR B 2 183 ? -5.276  -17.538 -8.127  1   41.3   ? 179 TYR A N   1 
ATOM   3527 C  CA  . TYR B 2 183 ? -6.519  -17.717 -7.386  1   41.4   ? 179 TYR A CA  1 
ATOM   3528 C  C   . TYR B 2 183 ? -6.49   -19.036 -6.626  1   38.13  ? 179 TYR A C   1 
ATOM   3529 O  O   . TYR B 2 183 ? -6.013  -20.069 -7.115  1   34.1   ? 179 TYR A O   1 
ATOM   3530 C  CB  . TYR B 2 183 ? -7.766  -17.853 -8.266  1   40.44  ? 179 TYR A CB  1 
ATOM   3531 C  CG  . TYR B 2 183 ? -8.074  -16.661 -9.142  1   42     ? 179 TYR A CG  1 
ATOM   3532 C  CD1 . TYR B 2 183 ? -8.337  -15.428 -8.561  1   43.8   ? 179 TYR A CD1 1 
ATOM   3533 C  CD2 . TYR B 2 183 ? -8.133  -16.785 -10.524 1   41.92  ? 179 TYR A CD2 1 
ATOM   3534 C  CE1 . TYR B 2 183 ? -8.654  -14.328 -9.345  1   48.85  ? 179 TYR A CE1 1 
ATOM   3535 C  CE2 . TYR B 2 183 ? -8.43   -15.686 -11.315 1   45.95  ? 179 TYR A CE2 1 
ATOM   3536 C  CZ  . TYR B 2 183 ? -8.686  -14.457 -10.724 1   50.2   ? 179 TYR A CZ  1 
ATOM   3537 O  OH  . TYR B 2 183 ? -9.01   -13.35  -11.461 1   53.78  ? 179 TYR A OH  1 
ATOM   3538 N  N   . TYR B 2 184 ? -7.042  -18.96  -5.422  1   37.97  ? 180 TYR A N   1 
ATOM   3539 C  CA  . TYR B 2 184 ? -7.205  -20.156 -4.624  1   41.02  ? 180 TYR A CA  1 
ATOM   3540 C  C   . TYR B 2 184 ? -8.564  -20.06  -3.944  1   41.82  ? 180 TYR A C   1 
ATOM   3541 O  O   . TYR B 2 184 ? -9.145  -18.965 -3.851  1   43.23  ? 180 TYR A O   1 
ATOM   3542 C  CB  . TYR B 2 184 ? -6.037  -20.424 -3.672  1   38.04  ? 180 TYR A CB  1 
ATOM   3543 C  CG  . TYR B 2 184 ? -5.881  -19.372 -2.584  1   36.89  ? 180 TYR A CG  1 
ATOM   3544 C  CD1 . TYR B 2 184 ? -6.717  -19.353 -1.472  1   35.13  ? 180 TYR A CD1 1 
ATOM   3545 C  CD2 . TYR B 2 184 ? -4.854  -18.443 -2.653  1   37.21  ? 180 TYR A CD2 1 
ATOM   3546 C  CE1 . TYR B 2 184 ? -6.532  -18.432 -0.453  1   37.07  ? 180 TYR A CE1 1 
ATOM   3547 C  CE2 . TYR B 2 184 ? -4.679  -17.499 -1.652  1   39.94  ? 180 TYR A CE2 1 
ATOM   3548 C  CZ  . TYR B 2 184 ? -5.516  -17.487 -0.55   1   39.03  ? 180 TYR A CZ  1 
ATOM   3549 O  OH  . TYR B 2 184 ? -5.317  -16.506 0.379   1   40.9   ? 180 TYR A OH  1 
ATOM   3550 N  N   . SER B 2 185 ? -9.05   -21.233 -3.515  1   37.76  ? 181 SER A N   1 
ATOM   3551 C  CA  . SER B 2 185 ? -10.416 -21.312 -3.05   1   39.38  ? 181 SER A CA  1 
ATOM   3552 C  C   . SER B 2 185 ? -10.523 -22.293 -1.894  1   36.41  ? 181 SER A C   1 
ATOM   3553 O  O   . SER B 2 185 ? -9.541  -22.569 -1.215  1   39.14  ? 181 SER A O   1 
ATOM   3554 C  CB  . SER B 2 185 ? -11.354 -21.639 -4.195  1   38.94  ? 181 SER A CB  1 
ATOM   3555 O  OG  . SER B 2 185 ? -12.695 -21.405 -3.786  1   42.8   ? 181 SER A OG  1 
ATOM   3556 N  N   . THR B 2 186 ? -11.731 -22.815 -1.713  1   33.29  ? 182 THR A N   1 
ATOM   3557 C  CA  . THR B 2 186 ? -12.114 -23.596 -0.548  1   33.18  ? 182 THR A CA  1 
ATOM   3558 C  C   . THR B 2 186 ? -11.254 -24.847 -0.492  1   32.8   ? 182 THR A C   1 
ATOM   3559 O  O   . THR B 2 186 ? -11.053 -25.387 0.577   1   34.83  ? 182 THR A O   1 
ATOM   3560 C  CB  . THR B 2 186 ? -13.614 -23.935 -0.639  1   33.96  ? 182 THR A CB  1 
ATOM   3561 O  OG1 . THR B 2 186 ? -13.873 -24.509 -1.925  1   32.46  ? 182 THR A OG1 1 
ATOM   3562 C  CG2 . THR B 2 186 ? -14.522 -22.73  -0.448  1   28.58  ? 182 THR A CG2 1 
ATOM   3563 N  N   . ALA B 2 187 ? -10.774 -25.3   -1.656  1   34.23  ? 183 ALA A N   1 
ATOM   3564 C  CA  . ALA B 2 187 ? -9.943  -26.485 -1.797  1   34.13  ? 183 ALA A CA  1 
ATOM   3565 C  C   . ALA B 2 187 ? -8.658  -26.397 -0.955  1   38.18  ? 183 ALA A C   1 
ATOM   3566 O  O   . ALA B 2 187 ? -8.146  -27.439 -0.536  1   37.67  ? 183 ALA A O   1 
ATOM   3567 C  CB  . ALA B 2 187 ? -9.624  -26.709 -3.252  1   31.27  ? 183 ALA A CB  1 
ATOM   3568 N  N   . VAL B 2 188 ? -8.13   -25.182 -0.7    1   35.11  ? 184 VAL A N   1 
ATOM   3569 C  CA  . VAL B 2 188 ? -6.915  -25.104 0.097   1   36.59  ? 184 VAL A CA  1 
ATOM   3570 C  C   . VAL B 2 188 ? -7.216  -25.636 1.504   1   39.61  ? 184 VAL A C   1 
ATOM   3571 O  O   . VAL B 2 188 ? -6.326  -26.214 2.14    1   41.87  ? 184 VAL A O   1 
ATOM   3572 C  CB  . VAL B 2 188 ? -6.234  -23.722 0.145   1   34.8   ? 184 VAL A CB  1 
ATOM   3573 C  CG1 . VAL B 2 188 ? -6.177  -23.052 -1.221  1   31.22  ? 184 VAL A CG1 1 
ATOM   3574 C  CG2 . VAL B 2 188 ? -6.906  -22.799 1.142   1   33.33  ? 184 VAL A CG2 1 
ATOM   3575 N  N   . ASP B 2 189 ? -8.464  -25.447 1.992   1   36.33  ? 185 ASP A N   1 
ATOM   3576 C  CA  . ASP B 2 189 ? -8.783  -25.893 3.342   1   34.89  ? 185 ASP A CA  1 
ATOM   3577 C  C   . ASP B 2 189 ? -8.929  -27.412 3.346   1   36.01  ? 185 ASP A C   1 
ATOM   3578 O  O   . ASP B 2 189 ? -8.549  -28.078 4.308   1   38.81  ? 185 ASP A O   1 
ATOM   3579 C  CB  . ASP B 2 189 ? -9.968  -25.192 3.987   1   35.92  ? 185 ASP A CB  1 
ATOM   3580 C  CG  . ASP B 2 189 ? -9.8    -23.744 4.437   1   41.93  ? 185 ASP A CG  1 
ATOM   3581 O  OD1 . ASP B 2 189 ? -8.641  -23.304 4.681   1   40.54  ? 185 ASP A OD1 1 
ATOM   3582 O  OD2 . ASP B 2 189 ? -10.862 -23.043 4.551   1   48.31  ? 185 ASP A OD2 1 
ATOM   3583 N  N   . ILE B 2 190 ? -9.44   -27.984 2.257   1   36.85  ? 186 ILE A N   1 
ATOM   3584 C  CA  . ILE B 2 190 ? -9.506  -29.438 2.209   1   38.45  ? 186 ILE A CA  1 
ATOM   3585 C  C   . ILE B 2 190 ? -8.099  -30.053 2.242   1   39.7   ? 186 ILE A C   1 
ATOM   3586 O  O   . ILE B 2 190 ? -7.849  -31.018 2.983   1   37.55  ? 186 ILE A O   1 
ATOM   3587 C  CB  . ILE B 2 190 ? -10.339 -29.933 1.022   1   36.44  ? 186 ILE A CB  1 
ATOM   3588 C  CG1 . ILE B 2 190 ? -11.839 -29.61  1.237   1   38.8   ? 186 ILE A CG1 1 
ATOM   3589 C  CG2 . ILE B 2 190 ? -10.117 -31.432 0.854   1   35.16  ? 186 ILE A CG2 1 
ATOM   3590 C  CD1 . ILE B 2 190 ? -12.487 -30.304 2.425   1   34.91  ? 186 ILE A CD1 1 
ATOM   3591 N  N   . TRP B 2 191 ? -7.185  -29.478 1.443   1   37.32  ? 187 TRP A N   1 
ATOM   3592 C  CA  . TRP B 2 191 ? -5.814  -29.956 1.438   1   40.7   ? 187 TRP A CA  1 
ATOM   3593 C  C   . TRP B 2 191 ? -5.328  -30.092 2.88    1   39.65  ? 187 TRP A C   1 
ATOM   3594 O  O   . TRP B 2 191 ? -4.872  -31.156 3.301   1   39.55  ? 187 TRP A O   1 
ATOM   3595 C  CB  . TRP B 2 191 ? -4.902  -29.044 0.605   1   39.62  ? 187 TRP A CB  1 
ATOM   3596 C  CG  . TRP B 2 191 ? -3.5    -29.575 0.516   1   42.67  ? 187 TRP A CG  1 
ATOM   3597 C  CD1 . TRP B 2 191 ? -2.489  -29.333 1.403   1   42.16  ? 187 TRP A CD1 1 
ATOM   3598 C  CD2 . TRP B 2 191 ? -2.965  -30.464 -0.492  1   40.45  ? 187 TRP A CD2 1 
ATOM   3599 N  NE1 . TRP B 2 191 ? -1.372  -30.017 1.021   1   40.68  ? 187 TRP A NE1 1 
ATOM   3600 C  CE2 . TRP B 2 191 ? -1.63   -30.713 -0.137  1   39.82  ? 187 TRP A CE2 1 
ATOM   3601 C  CE3 . TRP B 2 191 ? -3.469  -31.078 -1.638  1   38     ? 187 TRP A CE3 1 
ATOM   3602 C  CZ2 . TRP B 2 191 ? -0.807  -31.535 -0.907  1   39.68  ? 187 TRP A CZ2 1 
ATOM   3603 C  CZ3 . TRP B 2 191 ? -2.65   -31.893 -2.39   1   39.72  ? 187 TRP A CZ3 1 
ATOM   3604 C  CH2 . TRP B 2 191 ? -1.329  -32.129 -2.035  1   36.09  ? 187 TRP A CH2 1 
ATOM   3605 N  N   . SER B 2 192 ? -5.504  -29.024 3.656   1   38.56  ? 188 SER A N   1 
ATOM   3606 C  CA  . SER B 2 192 ? -5.009  -29.02  5.023   1   39.85  ? 188 SER A CA  1 
ATOM   3607 C  C   . SER B 2 192 ? -5.645  -30.148 5.846   1   38.1   ? 188 SER A C   1 
ATOM   3608 O  O   . SER B 2 192 ? -4.94   -30.829 6.584   1   40.18  ? 188 SER A O   1 
ATOM   3609 C  CB  . SER B 2 192 ? -5.123  -27.631 5.662   1   41.67  ? 188 SER A CB  1 
ATOM   3610 O  OG  . SER B 2 192 ? -4.316  -26.656 5.003   1   41     ? 188 SER A OG  1 
ATOM   3611 N  N   . LEU B 2 193 ? -6.96   -30.376 5.712   1   36.79  ? 189 LEU A N   1 
ATOM   3612 C  CA  . LEU B 2 193 ? -7.599  -31.464 6.443   1   39.38  ? 189 LEU A CA  1 
ATOM   3613 C  C   . LEU B 2 193 ? -7.063  -32.82  5.988   1   39.44  ? 189 LEU A C   1 
ATOM   3614 O  O   . LEU B 2 193 ? -7.024  -33.772 6.78    1   38.9   ? 189 LEU A O   1 
ATOM   3615 C  CB  . LEU B 2 193 ? -9.122  -31.483 6.329   1   40.34  ? 189 LEU A CB  1 
ATOM   3616 C  CG  . LEU B 2 193 ? -9.878  -30.314 6.956   1   43.67  ? 189 LEU A CG  1 
ATOM   3617 C  CD1 . LEU B 2 193 ? -11.357 -30.677 7.091   1   42.25  ? 189 LEU A CD1 1 
ATOM   3618 C  CD2 . LEU B 2 193 ? -9.273  -29.985 8.31    1   44.64  ? 189 LEU A CD2 1 
ATOM   3619 N  N   . GLY B 2 194 ? -6.75   -32.938 4.691   1   37.13  ? 190 GLY A N   1 
ATOM   3620 C  CA  . GLY B 2 194 ? -6.138  -34.169 4.204   1   37.47  ? 190 GLY A CA  1 
ATOM   3621 C  C   . GLY B 2 194 ? -4.818  -34.464 4.922   1   36.44  ? 190 GLY A C   1 
ATOM   3622 O  O   . GLY B 2 194 ? -4.61   -35.567 5.43    1   35.67  ? 190 GLY A O   1 
ATOM   3623 N  N   . CYS B 2 195 ? -3.952  -33.449 5.031   1   36     ? 191 CYS A N   1 
ATOM   3624 C  CA  . CYS B 2 195 ? -2.696  -33.656 5.733   1   36.09  ? 191 CYS A CA  1 
ATOM   3625 C  C   . CYS B 2 195 ? -2.992  -34.039 7.173   1   38.72  ? 191 CYS A C   1 
ATOM   3626 O  O   . CYS B 2 195 ? -2.358  -34.943 7.698   1   44.33  ? 191 CYS A O   1 
ATOM   3627 C  CB  . CYS B 2 195 ? -1.801  -32.433 5.654   1   33.73  ? 191 CYS A CB  1 
ATOM   3628 S  SG  . CYS B 2 195 ? -1.459  -31.945 3.947   1   36.17  ? 191 CYS A SG  1 
ATOM   3629 N  N   . ILE B 2 196 ? -3.958  -33.357 7.8     1   38.02  ? 192 ILE A N   1 
ATOM   3630 C  CA  . ILE B 2 196 ? -4.325  -33.602 9.186   1   39.73  ? 192 ILE A CA  1 
ATOM   3631 C  C   . ILE B 2 196 ? -4.842  -35.033 9.372   1   41.93  ? 192 ILE A C   1 
ATOM   3632 O  O   . ILE B 2 196 ? -4.528  -35.702 10.382  1   40.39  ? 192 ILE A O   1 
ATOM   3633 C  CB  . ILE B 2 196 ? -5.341  -32.545 9.655   1   38.91  ? 192 ILE A CB  1 
ATOM   3634 C  CG1 . ILE B 2 196 ? -4.646  -31.189 9.69    1   38.81  ? 192 ILE A CG1 1 
ATOM   3635 C  CG2 . ILE B 2 196 ? -5.952  -32.902 11.022  1   36.04  ? 192 ILE A CG2 1 
ATOM   3636 C  CD1 . ILE B 2 196 ? -5.559  -30.027 10.007  1   39.41  ? 192 ILE A CD1 1 
ATOM   3637 N  N   . PHE B 2 197 ? -5.659  -35.478 8.401   1   40.13  ? 193 PHE A N   1 
ATOM   3638 C  CA  . PHE B 2 197 ? -6.265  -36.808 8.421   1   37.5   ? 193 PHE A CA  1 
ATOM   3639 C  C   . PHE B 2 197 ? -5.147  -37.839 8.485   1   37.82  ? 193 PHE A C   1 
ATOM   3640 O  O   . PHE B 2 197 ? -5.176  -38.726 9.335   1   42.7   ? 193 PHE A O   1 
ATOM   3641 C  CB  . PHE B 2 197 ? -7.156  -37.021 7.192   1   35.14  ? 193 PHE A CB  1 
ATOM   3642 C  CG  . PHE B 2 197 ? -7.737  -38.417 7.036   1   35.65  ? 193 PHE A CG  1 
ATOM   3643 C  CD1 . PHE B 2 197 ? -7.732  -39.328 8.096   1   35.16  ? 193 PHE A CD1 1 
ATOM   3644 C  CD2 . PHE B 2 197 ? -8.311  -38.809 5.825   1   34.59  ? 193 PHE A CD2 1 
ATOM   3645 C  CE1 . PHE B 2 197 ? -8.282  -40.601 7.936   1   36.29  ? 193 PHE A CE1 1 
ATOM   3646 C  CE2 . PHE B 2 197 ? -8.892  -40.068 5.677   1   34.58  ? 193 PHE A CE2 1 
ATOM   3647 C  CZ  . PHE B 2 197 ? -8.886  -40.961 6.738   1   37.47  ? 193 PHE A CZ  1 
ATOM   3648 N  N   . ALA B 2 198 ? -4.136  -37.66  7.625   1   36.28  ? 194 ALA A N   1 
ATOM   3649 C  CA  . ALA B 2 198 ? -2.98   -38.541 7.604   1   36.86  ? 194 ALA A CA  1 
ATOM   3650 C  C   . ALA B 2 198 ? -2.202  -38.453 8.919   1   38.48  ? 194 ALA A C   1 
ATOM   3651 O  O   . ALA B 2 198 ? -1.806  -39.486 9.477   1   41.16  ? 194 ALA A O   1 
ATOM   3652 C  CB  . ALA B 2 198 ? -2.121  -38.254 6.39    1   34.41  ? 194 ALA A CB  1 
ATOM   3653 N  N   . GLU B 2 199 ? -2.057  -37.225 9.439   1   37.16  ? 195 GLU A N   1 
ATOM   3654 C  CA  . GLU B 2 199 ? -1.28   -36.993 10.649  1   42.11  ? 195 GLU A CA  1 
ATOM   3655 C  C   . GLU B 2 199 ? -1.937  -37.697 11.847  1   45.93  ? 195 GLU A C   1 
ATOM   3656 O  O   . GLU B 2 199 ? -1.243  -38.284 12.693  1   48.44  ? 195 GLU A O   1 
ATOM   3657 C  CB  . GLU B 2 199 ? -0.988  -35.493 10.806  1   39.86  ? 195 GLU A CB  1 
ATOM   3658 C  CG  . GLU B 2 199 ? -0.129  -35.13  12.019  1   37.94  ? 195 GLU A CG  1 
ATOM   3659 C  CD  . GLU B 2 199 ? 0.343   -33.688 12.027  1   38.32  ? 195 GLU A CD  1 
ATOM   3660 O  OE1 . GLU B 2 199 ? 0.129   -33.011 10.991  1   35.85  ? 195 GLU A OE1 1 
ATOM   3661 O  OE2 . GLU B 2 199 ? 0.927   -33.233 13.051  1   41.4   ? 195 GLU A OE2 1 
ATOM   3662 N  N   . MET B 2 200 ? -3.276  -37.636 11.917  1   46.31  ? 196 MET A N   1 
ATOM   3663 C  CA  . MET B 2 200 ? -4.007  -38.33  12.969  1   44.68  ? 196 MET A CA  1 
ATOM   3664 C  C   . MET B 2 200 ? -3.719  -39.827 12.954  1   42.78  ? 196 MET A C   1 
ATOM   3665 O  O   . MET B 2 200 ? -3.74   -40.429 14.007  1   43.03  ? 196 MET A O   1 
ATOM   3666 C  CB  . MET B 2 200 ? -5.52   -38.094 12.883  1   41.61  ? 196 MET A CB  1 
ATOM   3667 C  CG  . MET B 2 200 ? -5.932  -36.839 13.585  1   39.6   ? 196 MET A CG  1 
ATOM   3668 S  SD  . MET B 2 200 ? -7.711  -36.591 13.687  1   39.88  ? 196 MET A SD  1 
ATOM   3669 C  CE  . MET B 2 200 ? -8.327  -36.532 12.008  1   36.82  ? 196 MET A CE  1 
ATOM   3670 N  N   . VAL B 2 201 ? -3.395  -40.411 11.807  1   43.66  ? 197 VAL A N   1 
ATOM   3671 C  CA  . VAL B 2 201 ? -3.192  -41.888 11.744  1   45.87  ? 197 VAL A CA  1 
ATOM   3672 C  C   . VAL B 2 201 ? -1.724  -42.218 12.051  1   47.64  ? 197 VAL A C   1 
ATOM   3673 O  O   . VAL B 2 201 ? -1.482  -43.207 12.756  1   47.31  ? 197 VAL A O   1 
ATOM   3674 C  CB  . VAL B 2 201 ? -3.631  -42.448 10.379  1   43.59  ? 197 VAL A CB  1 
ATOM   3675 C  CG1 . VAL B 2 201 ? -3.433  -43.953 10.279  1   43.87  ? 197 VAL A CG1 1 
ATOM   3676 C  CG2 . VAL B 2 201 ? -5.069  -42.073 10.05   1   41.01  ? 197 VAL A CG2 1 
ATOM   3677 N  N   . THR B 2 202 ? -0.79   -41.392 11.586  1   50.8   ? 198 THR A N   1 
ATOM   3678 C  CA  . THR B 2 202 ? 0.65    -41.666 11.754  1   51.25  ? 198 THR A CA  1 
ATOM   3679 C  C   . THR B 2 202 ? 1.191   -40.939 12.955  1   51.96  ? 198 THR A C   1 
ATOM   3680 O  O   . THR B 2 202 ? 2.255   -41.355 13.438  1   53.47  ? 198 THR A O   1 
ATOM   3681 C  CB  . THR B 2 202 ? 1.36    -41.221 10.482  1   52.27  ? 198 THR A CB  1 
ATOM   3682 O  OG1 . THR B 2 202 ? 1.278   -39.801 10.486  1   59.19  ? 198 THR A OG1 1 
ATOM   3683 C  CG2 . THR B 2 202 ? 0.703   -41.772 9.231   1   54.93  ? 198 THR A CG2 1 
ATOM   3684 N  N   . ARG B 2 203 ? 0.509   -39.887 13.407  1   50.89  ? 199 ARG A N   1 
ATOM   3685 C  CA  . ARG B 2 203 ? 0.995   -39.047 14.537  1   54.37  ? 199 ARG A CA  1 
ATOM   3686 C  C   . ARG B 2 203 ? 2.249   -38.306 14.059  1   52.15  ? 199 ARG A C   1 
ATOM   3687 O  O   . ARG B 2 203 ? 2.971   -37.761 14.903  1   54.81  ? 199 ARG A O   1 
ATOM   3688 C  CB  . ARG B 2 203 ? 1.171   -39.846 15.832  1   60.24  ? 199 ARG A CB  1 
ATOM   3689 C  CG  . ARG B 2 203 ? -0.068  -39.887 16.713  1   64.99  ? 199 ARG A CG  1 
ATOM   3690 C  CD  . ARG B 2 203 ? -0.196  -41.226 17.405  1   64.15  ? 199 ARG A CD  1 
ATOM   3691 N  NE  . ARG B 2 203 ? -0.216  -42.314 16.423  1   72.75  ? 199 ARG A NE  1 
ATOM   3692 C  CZ  . ARG B 2 203 ? 0.637   -43.328 16.401  1   80.28  ? 199 ARG A CZ  1 
ATOM   3693 N  NH1 . ARG B 2 203 ? 1.594   -43.406 17.306  1   78.32  ? 199 ARG A NH1 1 
ATOM   3694 N  NH2 . ARG B 2 203 ? 0.528   -44.26  15.474  1   79.82  ? 199 ARG A NH2 1 
ATOM   3695 N  N   . ARG B 2 204 ? 2.483   -38.311 12.75   1   49.59  ? 200 ARG A N   1 
ATOM   3696 C  CA  . ARG B 2 204 ? 3.611   -37.556 12.164  1   50.28  ? 200 ARG A CA  1 
ATOM   3697 C  C   . ARG B 2 204 ? 3.075   -36.74  10.991  1   50.43  ? 200 ARG A C   1 
ATOM   3698 O  O   . ARG B 2 204 ? 2.113   -37.185 10.352  1   53.94  ? 200 ARG A O   1 
ATOM   3699 C  CB  . ARG B 2 204 ? 4.716   -38.445 11.592  1   53.45  ? 200 ARG A CB  1 
ATOM   3700 C  CG  . ARG B 2 204 ? 4.752   -39.898 12.034  1   58.75  ? 200 ARG A CG  1 
ATOM   3701 C  CD  . ARG B 2 204 ? 4.935   -40.831 10.851  1   66.82  ? 200 ARG A CD  1 
ATOM   3702 N  NE  . ARG B 2 204 ? 5.513   -40.171 9.676   1   62.9   ? 200 ARG A NE  1 
ATOM   3703 C  CZ  . ARG B 2 204 ? 6.196   -40.809 8.738   1   60.91  ? 200 ARG A CZ  1 
ATOM   3704 N  NH1 . ARG B 2 204 ? 5.599   -41.188 7.625   1   64.61  ? 200 ARG A NH1 1 
ATOM   3705 N  NH2 . ARG B 2 204 ? 7.475   -41.077 8.92    1   59.5   ? 200 ARG A NH2 1 
ATOM   3706 N  N   . ALA B 2 205 ? 3.701   -35.604 10.713  1   48.21  ? 201 ALA A N   1 
ATOM   3707 C  CA  . ALA B 2 205 ? 3.298   -34.783 9.555   1   43.92  ? 201 ALA A CA  1 
ATOM   3708 C  C   . ALA B 2 205 ? 3.566   -35.544 8.265   1   44.13  ? 201 ALA A C   1 
ATOM   3709 O  O   . ALA B 2 205 ? 4.544   -36.296 8.201   1   47.47  ? 201 ALA A O   1 
ATOM   3710 C  CB  . ALA B 2 205 ? 4.001   -33.458 9.576   1   41.14  ? 201 ALA A CB  1 
ATOM   3711 N  N   . LEU B 2 206 ? 2.723   -35.33  7.268   1   41.21  ? 202 LEU A N   1 
ATOM   3712 C  CA  . LEU B 2 206 ? 2.808   -36.025 5.996   1   40.52  ? 202 LEU A CA  1 
ATOM   3713 C  C   . LEU B 2 206 ? 3.823   -35.321 5.1     1   42     ? 202 LEU A C   1 
ATOM   3714 O  O   . LEU B 2 206 ? 4.617   -35.98  4.43    1   48.36  ? 202 LEU A O   1 
ATOM   3715 C  CB  . LEU B 2 206 ? 1.414   -35.989 5.36    1   37.09  ? 202 LEU A CB  1 
ATOM   3716 C  CG  . LEU B 2 206 ? 1.222   -36.762 4.049   1   36.63  ? 202 LEU A CG  1 
ATOM   3717 C  CD1 . LEU B 2 206 ? 1.296   -38.281 4.253   1   36.93  ? 202 LEU A CD1 1 
ATOM   3718 C  CD2 . LEU B 2 206 ? -0.086  -36.37  3.389   1   36.94  ? 202 LEU A CD2 1 
ATOM   3719 N  N   . PHE B 2 207 ? 3.81    -33.981 5.101   1   38.85  ? 203 PHE A N   1 
ATOM   3720 C  CA  . PHE B 2 207 ? 4.752   -33.27  4.263   1   36.65  ? 203 PHE A CA  1 
ATOM   3721 C  C   . PHE B 2 207 ? 5.568   -32.269 5.072   1   37.74  ? 203 PHE A C   1 
ATOM   3722 O  O   . PHE B 2 207 ? 5.406   -31.062 4.884   1   44.25  ? 203 PHE A O   1 
ATOM   3723 C  CB  . PHE B 2 207 ? 3.971   -32.536 3.185   1   34.97  ? 203 PHE A CB  1 
ATOM   3724 C  CG  . PHE B 2 207 ? 3.115   -33.458 2.346   1   37.23  ? 203 PHE A CG  1 
ATOM   3725 C  CD1 . PHE B 2 207 ? 3.665   -34.603 1.777   1   37.98  ? 203 PHE A CD1 1 
ATOM   3726 C  CD2 . PHE B 2 207 ? 1.759   -33.161 2.128   1   36     ? 203 PHE A CD2 1 
ATOM   3727 C  CE1 . PHE B 2 207 ? 2.878   -35.432 0.988   1   38.79  ? 203 PHE A CE1 1 
ATOM   3728 C  CE2 . PHE B 2 207 ? 0.97    -33.988 1.339   1   34.95  ? 203 PHE A CE2 1 
ATOM   3729 C  CZ  . PHE B 2 207 ? 1.536   -35.117 0.758   1   37.82  ? 203 PHE A CZ  1 
ATOM   3730 N  N   . PRO B 2 208 ? 6.545   -32.73  5.898   1   36.66  ? 204 PRO A N   1 
ATOM   3731 C  CA  . PRO B 2 208 ? 7.297   -31.831 6.758   1   36.86  ? 204 PRO A CA  1 
ATOM   3732 C  C   . PRO B 2 208 ? 8.402   -31.095 6.025   1   39.48  ? 204 PRO A C   1 
ATOM   3733 O  O   . PRO B 2 208 ? 9.584   -31.38  6.236   1   40.41  ? 204 PRO A O   1 
ATOM   3734 C  CB  . PRO B 2 208 ? 7.806   -32.789 7.832   1   35.78  ? 204 PRO A CB  1 
ATOM   3735 C  CG  . PRO B 2 208 ? 8.116   -34.059 7.098   1   34.62  ? 204 PRO A CG  1 
ATOM   3736 C  CD  . PRO B 2 208 ? 7.051   -34.116 6.039   1   34.45  ? 204 PRO A CD  1 
ATOM   3737 N  N   . GLY B 2 209 ? 8.021   -30.115 5.218   1   37.71  ? 205 GLY A N   1 
ATOM   3738 C  CA  . GLY B 2 209 ? 8.989   -29.372 4.401   1   40.49  ? 205 GLY A CA  1 
ATOM   3739 C  C   . GLY B 2 209 ? 9.816   -28.369 5.164   1   42.57  ? 205 GLY A C   1 
ATOM   3740 O  O   . GLY B 2 209 ? 9.368   -27.91  6.223   1   41.53  ? 205 GLY A O   1 
ATOM   3741 N  N   . ASP B 2 210 ? 10.985  -28.037 4.622   1   48.98  ? 206 ASP A N   1 
ATOM   3742 C  CA  . ASP B 2 210 ? 11.909  -27.075 5.275   1   59.09  ? 206 ASP A CA  1 
ATOM   3743 C  C   . ASP B 2 210 ? 11.896  -25.766 4.493   1   56.25  ? 206 ASP A C   1 
ATOM   3744 O  O   . ASP B 2 210 ? 12.424  -24.771 5.005   1   60.1   ? 206 ASP A O   1 
ATOM   3745 C  CB  . ASP B 2 210 ? 13.307  -27.659 5.36    1   66.75  ? 206 ASP A CB  1 
ATOM   3746 C  CG  . ASP B 2 210 ? 13.373  -29.159 5.603   1   79.72  ? 206 ASP A CG  1 
ATOM   3747 O  OD1 . ASP B 2 210 ? 12.816  -29.612 6.621   1   93.35  ? 206 ASP A OD1 1 
ATOM   3748 O  OD2 . ASP B 2 210 ? 13.984  -29.861 4.776   1   74.25  ? 206 ASP A OD2 1 
ATOM   3749 N  N   . SER B 2 211 ? 11.295  -25.775 3.308   1   49.77  ? 207 SER A N   1 
ATOM   3750 C  CA  . SER B 2 211 ? 11.274  -24.577 2.442   1   47.03  ? 207 SER A CA  1 
ATOM   3751 C  C   . SER B 2 211 ? 10.089  -24.667 1.481   1   45.01  ? 207 SER A C   1 
ATOM   3752 O  O   . SER B 2 211 ? 9.52    -25.754 1.366   1   42.86  ? 207 SER A O   1 
ATOM   3753 C  CB  . SER B 2 211 ? 12.571  -24.471 1.692   1   49.9   ? 207 SER A CB  1 
ATOM   3754 O  OG  . SER B 2 211 ? 12.647  -25.41  0.632   1   50.69  ? 207 SER A OG  1 
ATOM   3755 N  N   . GLU B 2 212 ? 9.729   -23.561 0.828   1   46.51  ? 208 GLU A N   1 
ATOM   3756 C  CA  . GLU B 2 212 ? 8.688   -23.67  -0.192  1   46.03  ? 208 GLU A CA  1 
ATOM   3757 C  C   . GLU B 2 212 ? 9.022   -24.796 -1.187  1   43.74  ? 208 GLU A C   1 
ATOM   3758 O  O   . GLU B 2 212 ? 8.213   -25.678 -1.404  1   40.1   ? 208 GLU A O   1 
ATOM   3759 C  CB  . GLU B 2 212 ? 8.459   -22.316 -0.86   1   47.74  ? 208 GLU A CB  1 
ATOM   3760 C  CG  . GLU B 2 212 ? 7.372   -21.468 -0.209  1   49.84  ? 208 GLU A CG  1 
ATOM   3761 C  CD  . GLU B 2 212 ? 7.327   -20.033 -0.713  1   54.5   ? 208 GLU A CD  1 
ATOM   3762 O  OE1 . GLU B 2 212 ? 6.26    -19.608 -1.227  1   53.82  ? 208 GLU A OE1 1 
ATOM   3763 O  OE2 . GLU B 2 212 ? 8.364   -19.327 -0.596  1   57.19  ? 208 GLU A OE2 1 
ATOM   3764 N  N   . ILE B 2 213 ? 10.238  -24.845 -1.724  1   43.35  ? 209 ILE A N   1 
ATOM   3765 C  CA  . ILE B 2 213 ? 10.562  -25.86  -2.776  1   42.31  ? 209 ILE A CA  1 
ATOM   3766 C  C   . ILE B 2 213 ? 10.628  -27.281 -2.182  1   42.77  ? 209 ILE A C   1 
ATOM   3767 O  O   . ILE B 2 213 ? 10.249  -28.218 -2.893  1   44.12  ? 209 ILE A O   1 
ATOM   3768 C  CB  . ILE B 2 213 ? 11.841  -25.476 -3.551  1   43.94  ? 209 ILE A CB  1 
ATOM   3769 C  CG1 . ILE B 2 213 ? 11.91   -26.185 -4.897  1   44.73  ? 209 ILE A CG1 1 
ATOM   3770 C  CG2 . ILE B 2 213 ? 13.103  -25.715 -2.725  1   46.12  ? 209 ILE A CG2 1 
ATOM   3771 C  CD1 . ILE B 2 213 ? 10.733  -25.897 -5.808  1   42.63  ? 209 ILE A CD1 1 
ATOM   3772 N  N   . ASP B 2 214 ? 11.061  -27.433 -0.932  1   42.23  ? 210 ASP A N   1 
ATOM   3773 C  CA  . ASP B 2 214 ? 11.189  -28.776 -0.307  1   40.82  ? 210 ASP A CA  1 
ATOM   3774 C  C   . ASP B 2 214 ? 9.791   -29.332 -0.047  1   40.16  ? 210 ASP A C   1 
ATOM   3775 O  O   . ASP B 2 214 ? 9.578   -30.519 -0.305  1   40.62  ? 210 ASP A O   1 
ATOM   3776 C  CB  . ASP B 2 214 ? 12.071  -28.742 0.93    1   43.52  ? 210 ASP A CB  1 
ATOM   3777 C  CG  . ASP B 2 214 ? 12.236  -30.066 1.655   1   47.14  ? 210 ASP A CG  1 
ATOM   3778 O  OD1 . ASP B 2 214 ? 12.803  -30.996 1.052   1   47.19  ? 210 ASP A OD1 1 
ATOM   3779 O  OD2 . ASP B 2 214 ? 11.792  -30.151 2.813   1   45.48  ? 210 ASP A OD2 1 
ATOM   3780 N  N   . GLN B 2 215 ? 8.881   -28.497 0.44    1   41.25  ? 211 GLN A N   1 
ATOM   3781 C  CA  . GLN B 2 215 ? 7.476   -28.924 0.628   1   39.65  ? 211 GLN A CA  1 
ATOM   3782 C  C   . GLN B 2 215 ? 6.93    -29.455 -0.697  1   38.22  ? 211 GLN A C   1 
ATOM   3783 O  O   . GLN B 2 215 ? 6.4     -30.566 -0.702  1   37.31  ? 211 GLN A O   1 
ATOM   3784 C  CB  . GLN B 2 215 ? 6.643   -27.734 1.094   1   40.17  ? 211 GLN A CB  1 
ATOM   3785 C  CG  . GLN B 2 215 ? 5.207   -28.083 1.452   1   39.7   ? 211 GLN A CG  1 
ATOM   3786 C  CD  . GLN B 2 215 ? 5.097   -28.662 2.839   1   41.5   ? 211 GLN A CD  1 
ATOM   3787 O  OE1 . GLN B 2 215 ? 5.964   -28.45  3.691   1   40.76  ? 211 GLN A OE1 1 
ATOM   3788 N  NE2 . GLN B 2 215 ? 4.022   -29.392 3.077   1   38.16  ? 211 GLN A NE2 1 
ATOM   3789 N  N   . LEU B 2 216 ? 7.073   -28.682 -1.766  1   38.26  ? 212 LEU A N   1 
ATOM   3790 C  CA  . LEU B 2 216 ? 6.56    -29.087 -3.097  1   40.79  ? 212 LEU A CA  1 
ATOM   3791 C  C   . LEU B 2 216 ? 7.177   -30.421 -3.517  1   41.22  ? 212 LEU A C   1 
ATOM   3792 O  O   . LEU B 2 216 ? 6.441   -31.294 -3.981  1   36.25  ? 212 LEU A O   1 
ATOM   3793 C  CB  . LEU B 2 216 ? 6.917   -27.982 -4.083  1   41.24  ? 212 LEU A CB  1 
ATOM   3794 C  CG  . LEU B 2 216 ? 6.546   -28.214 -5.547  1   43.06  ? 212 LEU A CG  1 
ATOM   3795 C  CD1 . LEU B 2 216 ? 5.041   -28.315 -5.604  1   41.98  ? 212 LEU A CD1 1 
ATOM   3796 C  CD2 . LEU B 2 216 ? 7.049   -27.1   -6.44   1   38.68  ? 212 LEU A CD2 1 
ATOM   3797 N  N   . PHE B 2 217 ? 8.481   -30.561 -3.33   1   37.25  ? 213 PHE A N   1 
ATOM   3798 C  CA  . PHE B 2 217 ? 9.18    -31.783 -3.791  1   37.17  ? 213 PHE A CA  1 
ATOM   3799 C  C   . PHE B 2 217 ? 8.737   -32.956 -2.942  1   37.18  ? 213 PHE A C   1 
ATOM   3800 O  O   . PHE B 2 217 ? 8.546   -34.036 -3.486  1   38.67  ? 213 PHE A O   1 
ATOM   3801 C  CB  . PHE B 2 217 ? 10.672  -31.444 -3.792  1   37.17  ? 213 PHE A CB  1 
ATOM   3802 C  CG  . PHE B 2 217 ? 11.159  -30.631 -4.981  1   37.55  ? 213 PHE A CG  1 
ATOM   3803 C  CD1 . PHE B 2 217 ? 10.277  -30.197 -5.961  1   35.84  ? 213 PHE A CD1 1 
ATOM   3804 C  CD2 . PHE B 2 217 ? 12.501  -30.303 -5.112  1   39.22  ? 213 PHE A CD2 1 
ATOM   3805 C  CE1 . PHE B 2 217 ? 10.727  -29.457 -7.038  1   36.91  ? 213 PHE A CE1 1 
ATOM   3806 C  CE2 . PHE B 2 217 ? 12.945  -29.563 -6.193  1   38.89  ? 213 PHE A CE2 1 
ATOM   3807 C  CZ  . PHE B 2 217 ? 12.058  -29.142 -7.151  1   38.47  ? 213 PHE A CZ  1 
ATOM   3808 N  N   . ARG B 2 218 ? 8.521   -32.731 -1.654  1   36.58  ? 214 ARG A N   1 
ATOM   3809 C  CA  . ARG B 2 218 ? 8.06    -33.81  -0.748  1   38.79  ? 214 ARG A CA  1 
ATOM   3810 C  C   . ARG B 2 218 ? 6.648   -34.242 -1.154  1   38.4   ? 214 ARG A C   1 
ATOM   3811 O  O   . ARG B 2 218 ? 6.354   -35.439 -1.06   1   40.42  ? 214 ARG A O   1 
ATOM   3812 C  CB  . ARG B 2 218 ? 8.109   -33.329 0.7     1   37.21  ? 214 ARG A CB  1 
ATOM   3813 C  CG  . ARG B 2 218 ? 9.435   -33.466 1.427   1   38.52  ? 214 ARG A CG  1 
ATOM   3814 C  CD  . ARG B 2 218 ? 9.303   -32.859 2.806   1   40.23  ? 214 ARG A CD  1 
ATOM   3815 N  NE  . ARG B 2 218 ? 10.608  -32.519 3.375   1   40.78  ? 214 ARG A NE  1 
ATOM   3816 C  CZ  . ARG B 2 218 ? 11.236  -33.254 4.273   1   39.64  ? 214 ARG A CZ  1 
ATOM   3817 N  NH1 . ARG B 2 218 ? 10.751  -34.432 4.615   1   38.76  ? 214 ARG A NH1 1 
ATOM   3818 N  NH2 . ARG B 2 218 ? 12.343  -32.806 4.83    1   37.85  ? 214 ARG A NH2 1 
ATOM   3819 N  N   . ILE B 2 219 ? 5.819   -33.298 -1.581  1   35.68  ? 215 ILE A N   1 
ATOM   3820 C  CA  . ILE B 2 219 ? 4.456   -33.634 -2.073  1   36.74  ? 215 ILE A CA  1 
ATOM   3821 C  C   . ILE B 2 219 ? 4.599   -34.445 -3.371  1   38.19  ? 215 ILE A C   1 
ATOM   3822 O  O   . ILE B 2 219 ? 3.881   -35.441 -3.52   1   40.87  ? 215 ILE A O   1 
ATOM   3823 C  CB  . ILE B 2 219 ? 3.605   -32.364 -2.255  1   34.98  ? 215 ILE A CB  1 
ATOM   3824 C  CG1 . ILE B 2 219 ? 3.374   -31.649 -0.929  1   36.8   ? 215 ILE A CG1 1 
ATOM   3825 C  CG2 . ILE B 2 219 ? 2.288   -32.676 -2.961  1   30.28  ? 215 ILE A CG2 1 
ATOM   3826 C  CD1 . ILE B 2 219 ? 2.887   -30.22  -1.071  1   37.36  ? 215 ILE A CD1 1 
ATOM   3827 N  N   . PHE B 2 220 ? 5.528   -34.049 -4.245  1   37.61  ? 216 PHE A N   1 
ATOM   3828 C  CA  . PHE B 2 220 ? 5.706   -34.798 -5.52   1   36.55  ? 216 PHE A CA  1 
ATOM   3829 C  C   . PHE B 2 220 ? 6.292   -36.172 -5.222  1   38.14  ? 216 PHE A C   1 
ATOM   3830 O  O   . PHE B 2 220 ? 5.971   -37.142 -5.932  1   39.77  ? 216 PHE A O   1 
ATOM   3831 C  CB  . PHE B 2 220 ? 6.654   -34.087 -6.488  1   36.28  ? 216 PHE A CB  1 
ATOM   3832 C  CG  . PHE B 2 220 ? 6.259   -32.681 -6.914  1   35.33  ? 216 PHE A CG  1 
ATOM   3833 C  CD1 . PHE B 2 220 ? 4.993   -32.176 -6.647  1   33.64  ? 216 PHE A CD1 1 
ATOM   3834 C  CD2 . PHE B 2 220 ? 7.163   -31.871 -7.592  1   35.78  ? 216 PHE A CD2 1 
ATOM   3835 C  CE1 . PHE B 2 220 ? 4.647   -30.893 -7.037  1   34.28  ? 216 PHE A CE1 1 
ATOM   3836 C  CE2 . PHE B 2 220 ? 6.809   -30.592 -7.984  1   36.41  ? 216 PHE A CE2 1 
ATOM   3837 C  CZ  . PHE B 2 220 ? 5.552   -30.109 -7.711  1   36.05  ? 216 PHE A CZ  1 
ATOM   3838 N  N   . ARG B 2 221 ? 7.132   -36.261 -4.189  1   37.96  ? 217 ARG A N   1 
ATOM   3839 C  CA  . ARG B 2 221 ? 7.801   -37.548 -3.864  1   39.23  ? 217 ARG A CA  1 
ATOM   3840 C  C   . ARG B 2 221 ? 6.794   -38.519 -3.227  1   40.84  ? 217 ARG A C   1 
ATOM   3841 O  O   . ARG B 2 221 ? 7.199   -39.653 -2.893  1   43.57  ? 217 ARG A O   1 
ATOM   3842 C  CB  . ARG B 2 221 ? 8.989   -37.294 -2.931  1   38.51  ? 217 ARG A CB  1 
ATOM   3843 C  CG  . ARG B 2 221 ? 10.144  -36.592 -3.629  1   40.93  ? 217 ARG A CG  1 
ATOM   3844 C  CD  . ARG B 2 221 ? 11.279  -36.275 -2.674  1   43.87  ? 217 ARG A CD  1 
ATOM   3845 N  NE  . ARG B 2 221 ? 11.058  -35.022 -1.945  1   47.67  ? 217 ARG A NE  1 
ATOM   3846 C  CZ  . ARG B 2 221 ? 11.911  -34.008 -1.927  1   47.62  ? 217 ARG A CZ  1 
ATOM   3847 N  NH1 . ARG B 2 221 ? 11.827  -33.085 -0.986  1   46.01  ? 217 ARG A NH1 1 
ATOM   3848 N  NH2 . ARG B 2 221 ? 12.846  -33.918 -2.857  1   44.01  ? 217 ARG A NH2 1 
ATOM   3849 N  N   . THR B 2 222 ? 5.538   -38.092 -3.064  1   40.12  ? 218 THR A N   1 
ATOM   3850 C  CA  . THR B 2 222 ? 4.513   -38.948 -2.429  1   44.98  ? 218 THR A CA  1 
ATOM   3851 C  C   . THR B 2 222 ? 3.354   -39.134 -3.379  1   48.21  ? 218 THR A C   1 
ATOM   3852 O  O   . THR B 2 222 ? 2.824   -40.264 -3.445  1   55.85  ? 218 THR A O   1 
ATOM   3853 C  CB  . THR B 2 222 ? 4.054   -38.298 -1.125  1   46.96  ? 218 THR A CB  1 
ATOM   3854 O  OG1 . THR B 2 222 ? 5.175   -37.593 -0.602  1   48.35  ? 218 THR A OG1 1 
ATOM   3855 C  CG2 . THR B 2 222 ? 3.583   -39.317 -0.103  1   46.9   ? 218 THR A CG2 1 
ATOM   3856 N  N   . LEU B 2 223 ? 2.968   -38.078 -4.099  1   43.59  ? 219 LEU A N   1 
ATOM   3857 C  CA  . LEU B 2 223 ? 1.806   -38.149 -4.957  1   42.72  ? 219 LEU A CA  1 
ATOM   3858 C  C   . LEU B 2 223 ? 2.173   -38.162 -6.439  1   42.73  ? 219 LEU A C   1 
ATOM   3859 O  O   . LEU B 2 223 ? 1.28    -38.139 -7.284  1   45.02  ? 219 LEU A O   1 
ATOM   3860 C  CB  . LEU B 2 223 ? 1       -36.898 -4.616  1   45.6   ? 219 LEU A CB  1 
ATOM   3861 C  CG  . LEU B 2 223 ? 0.499   -36.807 -3.167  1   47.12  ? 219 LEU A CG  1 
ATOM   3862 C  CD1 . LEU B 2 223 ? -0.397  -35.573 -3.048  1   42.89  ? 219 LEU A CD1 1 
ATOM   3863 C  CD2 . LEU B 2 223 ? -0.252  -38.061 -2.694  1   43.26  ? 219 LEU A CD2 1 
ATOM   3864 N  N   . GLY B 2 224 ? 3.473   -38.157 -6.752  1   41.56  ? 220 GLY A N   1 
ATOM   3865 C  CA  . GLY B 2 224 ? 3.971   -38.047 -8.113  1   37.46  ? 220 GLY A CA  1 
ATOM   3866 C  C   . GLY B 2 224 ? 4.009   -36.584 -8.547  1   37.65  ? 220 GLY A C   1 
ATOM   3867 O  O   . GLY B 2 224 ? 3.219   -35.76  -8.076  1   37.18  ? 220 GLY A O   1 
ATOM   3868 N  N   . THR B 2 225 ? 4.856   -36.305 -9.498  1   37.44  ? 221 THR A N   1 
ATOM   3869 C  CA  . THR B 2 225 ? 4.996   -34.935 -9.969  1   39.32  ? 221 THR A CA  1 
ATOM   3870 C  C   . THR B 2 225 ? 3.847   -34.665 -10.911 1   44.5   ? 221 THR A C   1 
ATOM   3871 O  O   . THR B 2 225 ? 3.619   -35.457 -11.829 1   49.86  ? 221 THR A O   1 
ATOM   3872 C  CB  . THR B 2 225 ? 6.395   -34.686 -10.543 1   41.07  ? 221 THR A CB  1 
ATOM   3873 O  OG1 . THR B 2 225 ? 7.308   -35.031 -9.513  1   41.24  ? 221 THR A OG1 1 
ATOM   3874 C  CG2 . THR B 2 225 ? 6.57    -33.254 -11.014 1   39.36  ? 221 THR A CG2 1 
ATOM   3875 N  N   . PRO B 2 226 ? 3.07    -33.595 -10.644 1   46.74  ? 222 PRO A N   1 
ATOM   3876 C  CA  . PRO B 2 226 ? 1.934   -33.252 -11.487 1   44.16  ? 222 PRO A CA  1 
ATOM   3877 C  C   . PRO B 2 226 ? 2.155   -32.836 -12.966 1   44.27  ? 222 PRO A C   1 
ATOM   3878 O  O   . PRO B 2 226 ? 3.016   -32.022 -13.241 1   46.99  ? 222 PRO A O   1 
ATOM   3879 C  CB  . PRO B 2 226 ? 1.275   -32.156 -10.592 1   43.12  ? 222 PRO A CB  1 
ATOM   3880 C  CG  . PRO B 2 226 ? 2.41    -31.522 -9.861  1   41.26  ? 222 PRO A CG  1 
ATOM   3881 C  CD  . PRO B 2 226 ? 3.26    -32.714 -9.523  1   44.3   ? 222 PRO A CD  1 
ATOM   3882 N  N   . ASP B 2 227 ? 1.382   -33.413 -13.881 1   44.6   ? 223 ASP A N   1 
ATOM   3883 C  CA  . ASP B 2 227 ? 1.441   -33.102 -15.343 1   45.73  ? 223 ASP A CA  1 
ATOM   3884 C  C   . ASP B 2 227 ? 0.116   -32.495 -15.836 1   45.51  ? 223 ASP A C   1 
ATOM   3885 O  O   . ASP B 2 227 ? -0.777  -32.357 -15.024 1   40.39  ? 223 ASP A O   1 
ATOM   3886 C  CB  . ASP B 2 227 ? 1.876   -34.322 -16.146 1   47.79  ? 223 ASP A CB  1 
ATOM   3887 C  CG  . ASP B 2 227 ? 0.947   -35.52  -16.205 1   51.64  ? 223 ASP A CG  1 
ATOM   3888 O  OD1 . ASP B 2 227 ? -0.234  -35.365 -15.92  1   50.91  ? 223 ASP A OD1 1 
ATOM   3889 O  OD2 . ASP B 2 227 ? 1.423   -36.6   -16.559 1   55.65  ? 223 ASP A OD2 1 
ATOM   3890 N  N   . GLU B 2 228 ? 0.033   -32.172 -17.14  1   51.18  ? 224 GLU A N   1 
ATOM   3891 C  CA  . GLU B 2 228 ? -1.172  -31.573 -17.707 1   50.79  ? 224 GLU A CA  1 
ATOM   3892 C  C   . GLU B 2 228 ? -2.344  -32.557 -17.647 1   53.56  ? 224 GLU A C   1 
ATOM   3893 O  O   . GLU B 2 228 ? -3.502  -32.15  -17.518 1   56.09  ? 224 GLU A O   1 
ATOM   3894 C  CB  . GLU B 2 228 ? -0.904  -31.054 -19.117 1   49.55  ? 224 GLU A CB  1 
ATOM   3895 C  CG  . GLU B 2 228 ? -0.101  -29.761 -19.129 1   51.39  ? 224 GLU A CG  1 
ATOM   3896 C  CD  . GLU B 2 228 ? -0.844  -28.527 -18.631 1   54.59  ? 224 GLU A CD  1 
ATOM   3897 O  OE1 . GLU B 2 228 ? -2.103  -28.496 -18.637 1   51.36  ? 224 GLU A OE1 1 
ATOM   3898 O  OE2 . GLU B 2 228 ? -0.135  -27.585 -18.216 1   54.58  ? 224 GLU A OE2 1 
ATOM   3899 N  N   . VAL B 2 229 ? -2.03   -33.857 -17.679 1   53.03  ? 225 VAL A N   1 
ATOM   3900 C  CA  . VAL B 2 229 ? -3.044  -34.897 -17.613 1   54.1   ? 225 VAL A CA  1 
ATOM   3901 C  C   . VAL B 2 229 ? -3.753  -34.9   -16.254 1   52.37  ? 225 VAL A C   1 
ATOM   3902 O  O   . VAL B 2 229 ? -4.969  -34.89  -16.178 1   55.97  ? 225 VAL A O   1 
ATOM   3903 C  CB  . VAL B 2 229 ? -2.449  -36.282 -17.906 1   54.84  ? 225 VAL A CB  1 
ATOM   3904 C  CG1 . VAL B 2 229 ? -3.556  -37.329 -17.873 1   52.84  ? 225 VAL A CG1 1 
ATOM   3905 C  CG2 . VAL B 2 229 ? -1.685  -36.298 -19.228 1   53.35  ? 225 VAL A CG2 1 
ATOM   3906 N  N   . VAL B 2 230 ? -3.008  -34.955 -15.161 1   49.25  ? 226 VAL A N   1 
ATOM   3907 C  CA  . VAL B 2 230 ? -3.66   -35.032 -13.87  1   47.91  ? 226 VAL A CA  1 
ATOM   3908 C  C   . VAL B 2 230 ? -4.146  -33.65  -13.437 1   48.41  ? 226 VAL A C   1 
ATOM   3909 O  O   . VAL B 2 230 ? -5.08   -33.543 -12.648 1   53.06  ? 226 VAL A O   1 
ATOM   3910 C  CB  . VAL B 2 230 ? -2.779  -35.73  -12.814 1   46.4   ? 226 VAL A CB  1 
ATOM   3911 C  CG1 . VAL B 2 230 ? -2.513  -37.172 -13.162 1   49.65  ? 226 VAL A CG1 1 
ATOM   3912 C  CG2 . VAL B 2 230 ? -1.467  -35.011 -12.58  1   48.92  ? 226 VAL A CG2 1 
ATOM   3913 N  N   . TRP B 2 231 ? -3.526  -32.582 -13.944 1   45.42  ? 227 TRP A N   1 
ATOM   3914 C  CA  . TRP B 2 231 ? -3.864  -31.262 -13.426 1   43     ? 227 TRP A CA  1 
ATOM   3915 C  C   . TRP B 2 231 ? -3.733  -30.24  -14.543 1   44.45  ? 227 TRP A C   1 
ATOM   3916 O  O   . TRP B 2 231 ? -2.677  -29.644 -14.707 1   46     ? 227 TRP A O   1 
ATOM   3917 C  CB  . TRP B 2 231 ? -2.961  -30.91  -12.237 1   40.61  ? 227 TRP A CB  1 
ATOM   3918 C  CG  . TRP B 2 231 ? -3.216  -29.584 -11.575 1   41.46  ? 227 TRP A CG  1 
ATOM   3919 C  CD1 . TRP B 2 231 ? -4.229  -28.701 -11.798 1   43.07  ? 227 TRP A CD1 1 
ATOM   3920 C  CD2 . TRP B 2 231 ? -2.421  -28.998 -10.525 1   42.34  ? 227 TRP A CD2 1 
ATOM   3921 N  NE1 . TRP B 2 231 ? -4.12   -27.607 -10.982 1   40.99  ? 227 TRP A NE1 1 
ATOM   3922 C  CE2 . TRP B 2 231 ? -3.03   -27.768 -10.179 1   40.29  ? 227 TRP A CE2 1 
ATOM   3923 C  CE3 . TRP B 2 231 ? -1.266  -29.405 -9.844  1   40.34  ? 227 TRP A CE3 1 
ATOM   3924 C  CZ2 . TRP B 2 231 ? -2.529  -26.944 -9.182  1   37.5   ? 227 TRP A CZ2 1 
ATOM   3925 C  CZ3 . TRP B 2 231 ? -0.761  -28.592 -8.858  1   37.69  ? 227 TRP A CZ3 1 
ATOM   3926 C  CH2 . TRP B 2 231 ? -1.385  -27.381 -8.547  1   40.18  ? 227 TRP A CH2 1 
ATOM   3927 N  N   . PRO B 2 232 ? -4.771  -30.046 -15.383 1   48.12  ? 228 PRO A N   1 
ATOM   3928 C  CA  . PRO B 2 232 ? -4.672  -29.097 -16.501 1   49.79  ? 228 PRO A CA  1 
ATOM   3929 C  C   . PRO B 2 232 ? -4.361  -27.696 -15.97  1   49.07  ? 228 PRO A C   1 
ATOM   3930 O  O   . PRO B 2 232 ? -4.924  -27.303 -14.936 1   45.01  ? 228 PRO A O   1 
ATOM   3931 C  CB  . PRO B 2 232 ? -6.037  -29.194 -17.229 1   49.19  ? 228 PRO A CB  1 
ATOM   3932 C  CG  . PRO B 2 232 ? -6.647  -30.501 -16.703 1   48.12  ? 228 PRO A CG  1 
ATOM   3933 C  CD  . PRO B 2 232 ? -6.069  -30.747 -15.317 1   47.67  ? 228 PRO A CD  1 
ATOM   3934 N  N   . GLY B 2 233 ? -3.399  -27.012 -16.635 1   48.94  ? 229 GLY A N   1 
ATOM   3935 C  CA  . GLY B 2 233 ? -2.927  -25.691 -16.24  1   51.94  ? 229 GLY A CA  1 
ATOM   3936 C  C   . GLY B 2 233 ? -1.645  -25.67  -15.392 1   55.57  ? 229 GLY A C   1 
ATOM   3937 O  O   . GLY B 2 233 ? -0.952  -24.65  -15.38  1   60.11  ? 229 GLY A O   1 
ATOM   3938 N  N   . VAL B 2 234 ? -1.324  -26.774 -14.694 1   49.14  ? 230 VAL A N   1 
ATOM   3939 C  CA  . VAL B 2 234 ? -0.184  -26.843 -13.802 1   44.78  ? 230 VAL A CA  1 
ATOM   3940 C  C   . VAL B 2 234 ? 1.064   -26.277 -14.487 1   49.95  ? 230 VAL A C   1 
ATOM   3941 O  O   . VAL B 2 234 ? 1.734   -25.44  -13.882 1   52.89  ? 230 VAL A O   1 
ATOM   3942 C  CB  . VAL B 2 234 ? 0.06    -28.233 -13.191 1   40.19  ? 230 VAL A CB  1 
ATOM   3943 C  CG1 . VAL B 2 234 ? 0.622   -29.22  -14.206 1   38.76  ? 230 VAL A CG1 1 
ATOM   3944 C  CG2 . VAL B 2 234 ? 0.972   -28.148 -11.977 1   38.2   ? 230 VAL A CG2 1 
ATOM   3945 N  N   . THR B 2 235 ? 1.379   -26.715 -15.723 1   50.61  ? 231 THR A N   1 
ATOM   3946 C  CA  . THR B 2 235 ? 2.667   -26.369 -16.328 1   51.18  ? 231 THR A CA  1 
ATOM   3947 C  C   . THR B 2 235 ? 2.671   -24.896 -16.724 1   51.98  ? 231 THR A C   1 
ATOM   3948 O  O   . THR B 2 235 ? 3.688   -24.393 -17.177 1   57.38  ? 231 THR A O   1 
ATOM   3949 C  CB  . THR B 2 235 ? 3.1     -27.24  -17.516 1   48.9   ? 231 THR A CB  1 
ATOM   3950 O  OG1 . THR B 2 235 ? 2.25    -26.945 -18.612 1   53.51  ? 231 THR A OG1 1 
ATOM   3951 C  CG2 . THR B 2 235 ? 3.1     -28.736 -17.273 1   46.43  ? 231 THR A CG2 1 
ATOM   3952 N  N   . SER B 2 236 ? 1.535   -24.22  -16.572 1   54.6   ? 232 SER A N   1 
ATOM   3953 C  CA  . SER B 2 236 ? 1.385   -22.823 -16.97  1   64.9   ? 232 SER A CA  1 
ATOM   3954 C  C   . SER B 2 236 ? 1.551   -21.925 -15.754 1   64.06  ? 232 SER A C   1 
ATOM   3955 O  O   . SER B 2 236 ? 1.63    -20.715 -15.888 1   67.98  ? 232 SER A O   1 
ATOM   3956 C  CB  . SER B 2 236 ? 0.023   -22.548 -17.609 1   68.22  ? 232 SER A CB  1 
ATOM   3957 O  OG  . SER B 2 236 ? -0.033  -23.038 -18.942 1   78.81  ? 232 SER A OG  1 
ATOM   3958 N  N   . MET B 2 237 ? 1.582   -22.529 -14.568 1   61.07  ? 233 MET A N   1 
ATOM   3959 C  CA  . MET B 2 237 ? 1.407   -21.771 -13.342 1   57.65  ? 233 MET A CA  1 
ATOM   3960 C  C   . MET B 2 237 ? 2.629   -20.923 -13.014 1   56.14  ? 233 MET A C   1 
ATOM   3961 O  O   . MET B 2 237 ? 3.754   -21.284 -13.35  1   57.51  ? 233 MET A O   1 
ATOM   3962 C  CB  . MET B 2 237 ? 1.073   -22.701 -12.182 1   57.75  ? 233 MET A CB  1 
ATOM   3963 C  CG  . MET B 2 237 ? -0.381  -23     -12.207 1   61.96  ? 233 MET A CG  1 
ATOM   3964 S  SD  . MET B 2 237 ? -0.762  -24.46  -11.244 1   68.95  ? 233 MET A SD  1 
ATOM   3965 C  CE  . MET B 2 237 ? -2.431  -24.754 -11.87  1   69.72  ? 233 MET A CE  1 
ATOM   3966 N  N   . PRO B 2 238 ? 2.422   -19.773 -12.335 1   53.08  ? 234 PRO A N   1 
ATOM   3967 C  CA  . PRO B 2 238 ? 3.438   -18.733 -12.291 1   50.79  ? 234 PRO A CA  1 
ATOM   3968 C  C   . PRO B 2 238 ? 4.768   -19.239 -11.742 1   48.76  ? 234 PRO A C   1 
ATOM   3969 O  O   . PRO B 2 238 ? 5.81    -18.707 -12.127 1   54.45  ? 234 PRO A O   1 
ATOM   3970 C  CB  . PRO B 2 238 ? 2.8     -17.604 -11.445 1   49.79  ? 234 PRO A CB  1 
ATOM   3971 C  CG  . PRO B 2 238 ? 1.313   -17.928 -11.383 1   47.61  ? 234 PRO A CG  1 
ATOM   3972 C  CD  . PRO B 2 238 ? 1.209   -19.424 -11.565 1   49.29  ? 234 PRO A CD  1 
ATOM   3973 N  N   . ASP B 2 239 ? 4.739   -20.26  -10.869 1   45.39  ? 235 ASP A N   1 
ATOM   3974 C  CA  . ASP B 2 239 ? 5.965   -20.751 -10.245 1   47.11  ? 235 ASP A CA  1 
ATOM   3975 C  C   . ASP B 2 239 ? 6.253   -22.21  -10.599 1   47.84  ? 235 ASP A C   1 
ATOM   3976 O  O   . ASP B 2 239 ? 7.218   -22.778 -10.103 1   50.92  ? 235 ASP A O   1 
ATOM   3977 C  CB  . ASP B 2 239 ? 6.028   -20.436 -8.759  1   45.08  ? 235 ASP A CB  1 
ATOM   3978 C  CG  . ASP B 2 239 ? 6.183   -18.959 -8.442  1   46.07  ? 235 ASP A CG  1 
ATOM   3979 O  OD1 . ASP B 2 239 ? 6.936   -18.299 -9.142  1   51.68  ? 235 ASP A OD1 1 
ATOM   3980 O  OD2 . ASP B 2 239 ? 5.534   -18.467 -7.528  1   46.21  ? 235 ASP A OD2 1 
ATOM   3981 N  N   . TYR B 2 240 ? 5.454   -22.797 -11.491 1   46.72  ? 236 TYR A N   1 
ATOM   3982 C  CA  . TYR B 2 240 ? 5.874   -24.022 -12.154 1   47.6   ? 236 TYR A CA  1 
ATOM   3983 C  C   . TYR B 2 240 ? 7.215   -23.763 -12.844 1   48.09  ? 236 TYR A C   1 
ATOM   3984 O  O   . TYR B 2 240 ? 7.445   -22.674 -13.379 1   50.59  ? 236 TYR A O   1 
ATOM   3985 C  CB  . TYR B 2 240 ? 4.831   -24.515 -13.174 1   47.84  ? 236 TYR A CB  1 
ATOM   3986 C  CG  . TYR B 2 240 ? 5.225   -25.853 -13.778 1   49.65  ? 236 TYR A CG  1 
ATOM   3987 C  CD1 . TYR B 2 240 ? 4.902   -27.035 -13.122 1   52.33  ? 236 TYR A CD1 1 
ATOM   3988 C  CD2 . TYR B 2 240 ? 5.948   -25.942 -14.968 1   53.52  ? 236 TYR A CD2 1 
ATOM   3989 C  CE1 . TYR B 2 240 ? 5.273   -28.273 -13.623 1   56.8   ? 236 TYR A CE1 1 
ATOM   3990 C  CE2 . TYR B 2 240 ? 6.32    -27.176 -15.489 1   56.56  ? 236 TYR A CE2 1 
ATOM   3991 C  CZ  . TYR B 2 240 ? 5.998   -28.34  -14.804 1   60.34  ? 236 TYR A CZ  1 
ATOM   3992 O  OH  . TYR B 2 240 ? 6.365   -29.569 -15.28  1   67.36  ? 236 TYR A OH  1 
ATOM   3993 N  N   . LYS B 2 241 ? 8.072   -24.785 -12.852 1   45.98  ? 237 LYS A N   1 
ATOM   3994 C  CA  . LYS B 2 241 ? 9.328   -24.777 -13.593 1   47.75  ? 237 LYS A CA  1 
ATOM   3995 C  C   . LYS B 2 241 ? 9.399   -26.095 -14.366 1   45.54  ? 237 LYS A C   1 
ATOM   3996 O  O   . LYS B 2 241 ? 9.202   -27.155 -13.784 1   42.91  ? 237 LYS A O   1 
ATOM   3997 C  CB  . LYS B 2 241 ? 10.552  -24.643 -12.667 1   51.14  ? 237 LYS A CB  1 
ATOM   3998 C  CG  . LYS B 2 241 ? 10.567  -23.462 -11.719 1   54.5   ? 237 LYS A CG  1 
ATOM   3999 C  CD  . LYS B 2 241 ? 10.82   -22.14  -12.436 1   65.83  ? 237 LYS A CD  1 
ATOM   4000 C  CE  . LYS B 2 241 ? 10.684  -20.813 -11.705 1   72.01  ? 237 LYS A CE  1 
ATOM   4001 N  NZ  . LYS B 2 241 ? 9.348   -20.183 -11.708 1   74.32  ? 237 LYS A NZ  1 
ATOM   4002 N  N   . PRO B 2 242 ? 9.595   -26.102 -15.707 1   46.53  ? 238 PRO A N   1 
ATOM   4003 C  CA  . PRO B 2 242 ? 9.823   -27.359 -16.431 1   47.81  ? 238 PRO A CA  1 
ATOM   4004 C  C   . PRO B 2 242 ? 10.85   -28.328 -15.833 1   48.88  ? 238 PRO A C   1 
ATOM   4005 O  O   . PRO B 2 242 ? 10.691  -29.533 -15.983 1   51.56  ? 238 PRO A O   1 
ATOM   4006 C  CB  . PRO B 2 242 ? 10.226  -26.914 -17.862 1   47.62  ? 238 PRO A CB  1 
ATOM   4007 C  CG  . PRO B 2 242 ? 10.51   -25.424 -17.742 1   47.64  ? 238 PRO A CG  1 
ATOM   4008 C  CD  . PRO B 2 242 ? 9.606   -24.936 -16.608 1   46.36  ? 238 PRO A CD  1 
ATOM   4009 N  N   . SER B 2 243 ? 11.886  -27.803 -15.163 1   48.16  ? 239 SER A N   1 
ATOM   4010 C  CA  . SER B 2 243 ? 13.015  -28.588 -14.692 1   48.22  ? 239 SER A CA  1 
ATOM   4011 C  C   . SER B 2 243 ? 12.705  -29.304 -13.375 1   44.98  ? 239 SER A C   1 
ATOM   4012 O  O   . SER B 2 243 ? 13.54   -30.056 -12.883 1   45.87  ? 239 SER A O   1 
ATOM   4013 C  CB  . SER B 2 243 ? 14.246  -27.713 -14.575 1   51.1   ? 239 SER A CB  1 
ATOM   4014 O  OG  . SER B 2 243 ? 13.913  -26.582 -13.774 1   55.58  ? 239 SER A OG  1 
ATOM   4015 N  N   . PHE B 2 244 ? 11.528  -29.06  -12.791 1   42.08  ? 240 PHE A N   1 
ATOM   4016 C  CA  . PHE B 2 244 ? 11.045  -29.863 -11.673 1   40.91  ? 240 PHE A CA  1 
ATOM   4017 C  C   . PHE B 2 244 ? 11.24   -31.349 -11.955 1   40.98  ? 240 PHE A C   1 
ATOM   4018 O  O   . PHE B 2 244 ? 10.853  -31.868 -13.009 1   40.96  ? 240 PHE A O   1 
ATOM   4019 C  CB  . PHE B 2 244 ? 9.529   -29.785 -11.502 1   40.08  ? 240 PHE A CB  1 
ATOM   4020 C  CG  . PHE B 2 244 ? 9.068   -28.529 -10.785 1   42.42  ? 240 PHE A CG  1 
ATOM   4021 C  CD1 . PHE B 2 244 ? 9.988   -27.679 -10.161 1   42.57  ? 240 PHE A CD1 1 
ATOM   4022 C  CD2 . PHE B 2 244 ? 7.714   -28.216 -10.72  1   40.01  ? 240 PHE A CD2 1 
ATOM   4023 C  CE1 . PHE B 2 244 ? 9.539   -26.535 -9.51   1   41.37  ? 240 PHE A CE1 1 
ATOM   4024 C  CE2 . PHE B 2 244 ? 7.305   -27.074 -10.069 1   38.22  ? 240 PHE A CE2 1 
ATOM   4025 C  CZ  . PHE B 2 244 ? 8.209   -26.245 -9.462  1   38.03  ? 240 PHE A CZ  1 
ATOM   4026 N  N   . PRO B 2 245 ? 11.828  -32.093 -11.008 1   42.01  ? 241 PRO A N   1 
ATOM   4027 C  CA  . PRO B 2 245 ? 12.065  -33.519 -11.224 1   43.72  ? 241 PRO A CA  1 
ATOM   4028 C  C   . PRO B 2 245 ? 10.699  -34.182 -11.341 1   43.63  ? 241 PRO A C   1 
ATOM   4029 O  O   . PRO B 2 245 ? 9.702   -33.686 -10.802 1   41.54  ? 241 PRO A O   1 
ATOM   4030 C  CB  . PRO B 2 245 ? 12.86   -33.882 -9.952  1   43.39  ? 241 PRO A CB  1 
ATOM   4031 C  CG  . PRO B 2 245 ? 13.525  -32.578 -9.578  1   42.7   ? 241 PRO A CG  1 
ATOM   4032 C  CD  . PRO B 2 245 ? 12.353  -31.605 -9.726  1   41.93  ? 241 PRO A CD  1 
ATOM   4033 N  N   . LYS B 2 246 ? 10.654  -35.264 -12.121 1   46.65  ? 242 LYS A N   1 
ATOM   4034 C  CA  . LYS B 2 246 ? 9.396   -35.93  -12.452 1   47.7   ? 242 LYS A CA  1 
ATOM   4035 C  C   . LYS B 2 246 ? 9.312   -37.203 -11.617 1   46.79  ? 242 LYS A C   1 
ATOM   4036 O  O   . LYS B 2 246 ? 9.907   -38.201 -11.973 1   56.91  ? 242 LYS A O   1 
ATOM   4037 C  CB  . LYS B 2 246 ? 9.382   -36.326 -13.941 1   49.64  ? 242 LYS A CB  1 
ATOM   4038 C  CG  . LYS B 2 246 ? 8.79    -35.379 -14.955 1   57.37  ? 242 LYS A CG  1 
ATOM   4039 C  CD  . LYS B 2 246 ? 9.16    -33.907 -14.783 1   71.46  ? 242 LYS A CD  1 
ATOM   4040 C  CE  . LYS B 2 246 ? 8.623   -33.001 -15.859 1   72.54  ? 242 LYS A CE  1 
ATOM   4041 N  NZ  . LYS B 2 246 ? 8.872   -33.568 -17.195 1   66.93  ? 242 LYS A NZ  1 
ATOM   4042 N  N   . TRP B 2 247 ? 8.655   -37.169 -10.46  1   44.22  ? 243 TRP A N   1 
ATOM   4043 C  CA  . TRP B 2 247 ? 8.584   -38.372 -9.638  1   40.69  ? 243 TRP A CA  1 
ATOM   4044 C  C   . TRP B 2 247 ? 7.331   -39.178 -9.999  1   40.33  ? 243 TRP A C   1 
ATOM   4045 O  O   . TRP B 2 247 ? 6.263   -38.599 -10.271 1   37.67  ? 243 TRP A O   1 
ATOM   4046 C  CB  . TRP B 2 247 ? 8.654   -38.023 -8.144  1   36.99  ? 243 TRP A CB  1 
ATOM   4047 C  CG  . TRP B 2 247 ? 10.025  -37.662 -7.628  1   38.51  ? 243 TRP A CG  1 
ATOM   4048 C  CD1 . TRP B 2 247 ? 11.08   -38.499 -7.351  1   39.12  ? 243 TRP A CD1 1 
ATOM   4049 C  CD2 . TRP B 2 247 ? 10.461  -36.336 -7.26   1   38.02  ? 243 TRP A CD2 1 
ATOM   4050 N  NE1 . TRP B 2 247 ? 12.142  -37.789 -6.851  1   40.61  ? 243 TRP A NE1 1 
ATOM   4051 C  CE2 . TRP B 2 247 ? 11.786  -36.461 -6.78   1   40.71  ? 243 TRP A CE2 1 
ATOM   4052 C  CE3 . TRP B 2 247 ? 9.867   -35.072 -7.309  1   36.22  ? 243 TRP A CE3 1 
ATOM   4053 C  CZ2 . TRP B 2 247 ? 12.512  -35.346 -6.351  1   42.31  ? 243 TRP A CZ2 1 
ATOM   4054 C  CZ3 . TRP B 2 247 ? 10.573  -33.975 -6.876  1   37.53  ? 243 TRP A CZ3 1 
ATOM   4055 C  CH2 . TRP B 2 247 ? 11.877  -34.116 -6.398  1   40.39  ? 243 TRP A CH2 1 
ATOM   4056 N  N   . ALA B 2 248 ? 7.483   -40.514 -9.99   1   40.87  ? 244 ALA A N   1 
ATOM   4057 C  CA  . ALA B 2 248 ? 6.374   -41.44  -10.176 1   41.27  ? 244 ALA A CA  1 
ATOM   4058 C  C   . ALA B 2 248 ? 5.441   -41.363 -8.981  1   42.81  ? 244 ALA A C   1 
ATOM   4059 O  O   . ALA B 2 248 ? 5.883   -41.26  -7.842  1   46.98  ? 244 ALA A O   1 
ATOM   4060 C  CB  . ALA B 2 248 ? 6.875   -42.837 -10.339 1   40.17  ? 244 ALA A CB  1 
ATOM   4061 N  N   . ARG B 2 249 ? 4.14    -41.397 -9.246  1   44.49  ? 245 ARG A N   1 
ATOM   4062 C  CA  . ARG B 2 249 ? 3.194   -41.52  -8.154  1   46.52  ? 245 ARG A CA  1 
ATOM   4063 C  C   . ARG B 2 249 ? 3.373   -42.898 -7.519  1   52.61  ? 245 ARG A C   1 
ATOM   4064 O  O   . ARG B 2 249 ? 3.383   -43.912 -8.211  1   56.95  ? 245 ARG A O   1 
ATOM   4065 C  CB  . ARG B 2 249 ? 1.792   -41.323 -8.735  1   43.26  ? 245 ARG A CB  1 
ATOM   4066 C  CG  . ARG B 2 249 ? 0.733   -41.596 -7.686  1   44.14  ? 245 ARG A CG  1 
ATOM   4067 C  CD  . ARG B 2 249 ? -0.638  -41.209 -8.214  1   46     ? 245 ARG A CD  1 
ATOM   4068 N  NE  . ARG B 2 249 ? -1.617  -41.263 -7.119  1   47.09  ? 245 ARG A NE  1 
ATOM   4069 C  CZ  . ARG B 2 249 ? -2.089  -40.217 -6.45   1   47.9   ? 245 ARG A CZ  1 
ATOM   4070 N  NH1 . ARG B 2 249 ? -1.542  -39.007 -6.611  1   46.05  ? 245 ARG A NH1 1 
ATOM   4071 N  NH2 . ARG B 2 249 ? -3.109  -40.404 -5.619  1   46.54  ? 245 ARG A NH2 1 
ATOM   4072 N  N   . GLN B 2 250 ? 3.545   -42.948 -6.2    1   57.6   ? 246 GLN A N   1 
ATOM   4073 C  CA  . GLN B 2 250 ? 3.646   -44.242 -5.548  1   59.05  ? 246 GLN A CA  1 
ATOM   4074 C  C   . GLN B 2 250 ? 2.222   -44.715 -5.222  1   62.65  ? 246 GLN A C   1 
ATOM   4075 O  O   . GLN B 2 250 ? 1.305   -43.893 -5.091  1   54.66  ? 246 GLN A O   1 
ATOM   4076 C  CB  . GLN B 2 250 ? 4.617   -44.113 -4.371  1   56.35  ? 246 GLN A CB  1 
ATOM   4077 C  CG  . GLN B 2 250 ? 3.959   -43.562 -3.112  1   54.22  ? 246 GLN A CG  1 
ATOM   4078 C  CD  . GLN B 2 250 ? 4.952   -43.296 -2.003  1   62.43  ? 246 GLN A CD  1 
ATOM   4079 O  OE1 . GLN B 2 250 ? 4.893   -42.258 -1.328  1   63.85  ? 246 GLN A OE1 1 
ATOM   4080 N  NE2 . GLN B 2 250 ? 5.883   -44.228 -1.819  1   64.19  ? 246 GLN A NE2 1 
ATOM   4081 N  N   . ASP B 2 251 ? 2.053   -46.045 -5.127  1   67.08  ? 247 ASP A N   1 
ATOM   4082 C  CA  . ASP B 2 251 ? 0.806   -46.653 -4.692  1   66.38  ? 247 ASP A CA  1 
ATOM   4083 C  C   . ASP B 2 251 ? 0.358   -45.953 -3.413  1   61.01  ? 247 ASP A C   1 
ATOM   4084 O  O   . ASP B 2 251 ? 1.123   -45.815 -2.463  1   65.71  ? 247 ASP A O   1 
ATOM   4085 C  CB  . ASP B 2 251 ? 0.958   -48.156 -4.48   1   80.65  ? 247 ASP A CB  1 
ATOM   4086 C  CG  . ASP B 2 251 ? -0.343  -48.936 -4.296  1   95.31  ? 247 ASP A CG  1 
ATOM   4087 O  OD1 . ASP B 2 251 ? -0.985  -49.255 -5.322  1   97.87  ? 247 ASP A OD1 1 
ATOM   4088 O  OD2 . ASP B 2 251 ? -0.735  -49.202 -3.131  1   100.03 ? 247 ASP A OD2 1 
ATOM   4089 N  N   . PHE B 2 252 ? -0.898  -45.519 -3.391  1   56.02  ? 248 PHE A N   1 
ATOM   4090 C  CA  . PHE B 2 252 ? -1.449  -44.729 -2.305  1   49.92  ? 248 PHE A CA  1 
ATOM   4091 C  C   . PHE B 2 252 ? -1.524  -45.517 -0.994  1   50.88  ? 248 PHE A C   1 
ATOM   4092 O  O   . PHE B 2 252 ? -1.61   -44.929 0.087   1   54.99  ? 248 PHE A O   1 
ATOM   4093 C  CB  . PHE B 2 252 ? -2.837  -44.255 -2.751  1   47.9   ? 248 PHE A CB  1 
ATOM   4094 C  CG  . PHE B 2 252 ? -3.094  -42.923 -2.083  1   45.73  ? 248 PHE A CG  1 
ATOM   4095 C  CD1 . PHE B 2 252 ? -2.695  -41.747 -2.717  1   46.7   ? 248 PHE A CD1 1 
ATOM   4096 C  CD2 . PHE B 2 252 ? -3.602  -42.851 -0.803  1   42.54  ? 248 PHE A CD2 1 
ATOM   4097 C  CE1 . PHE B 2 252 ? -2.876  -40.512 -2.134  1   40.44  ? 248 PHE A CE1 1 
ATOM   4098 C  CE2 . PHE B 2 252 ? -3.755  -41.601 -0.214  1   47.89  ? 248 PHE A CE2 1 
ATOM   4099 C  CZ  . PHE B 2 252 ? -3.399  -40.439 -0.882  1   43.05  ? 248 PHE A CZ  1 
ATOM   4100 N  N   . SER B 2 253 ? -1.571  -46.855 -1.085  1   52.06  ? 249 SER A N   1 
ATOM   4101 C  CA  . SER B 2 253 ? -1.587  -47.711 0.094   1   48.8   ? 249 SER A CA  1 
ATOM   4102 C  C   . SER B 2 253 ? -0.267  -47.622 0.865   1   53.79  ? 249 SER A C   1 
ATOM   4103 O  O   . SER B 2 253 ? -0.15   -48.133 1.987   1   54.96  ? 249 SER A O   1 
ATOM   4104 C  CB  . SER B 2 253 ? -1.863  -49.103 -0.289  1   46.08  ? 249 SER A CB  1 
ATOM   4105 O  OG  . SER B 2 253 ? -0.659  -49.693 -0.724  1   50.66  ? 249 SER A OG  1 
ATOM   4106 N  N   . LYS B 2 254 ? 0.747   -46.988 0.254   1   56.5   ? 250 LYS A N   1 
ATOM   4107 C  CA  . LYS B 2 254 ? 2.074   -46.899 0.855   1   54.24  ? 250 LYS A CA  1 
ATOM   4108 C  C   . LYS B 2 254 ? 2.264   -45.548 1.552   1   52.64  ? 250 LYS A C   1 
ATOM   4109 O  O   . LYS B 2 254 ? 3.104   -45.419 2.427   1   51.56  ? 250 LYS A O   1 
ATOM   4110 C  CB  . LYS B 2 254 ? 3.109   -47.244 -0.212  1   53.95  ? 250 LYS A CB  1 
ATOM   4111 C  CG  . LYS B 2 254 ? 3.038   -48.692 -0.682  1   57.27  ? 250 LYS A CG  1 
ATOM   4112 C  CD  . LYS B 2 254 ? 3.572   -49.658 0.371   1   64.25  ? 250 LYS A CD  1 
ATOM   4113 C  CE  . LYS B 2 254 ? 3.516   -51.094 -0.021  1   65.13  ? 250 LYS A CE  1 
ATOM   4114 N  NZ  . LYS B 2 254 ? 2.112   -51.464 -0.189  1   68.31  ? 250 LYS A NZ  1 
ATOM   4115 N  N   . VAL B 2 255 ? 1.424   -44.562 1.217   1   50.89  ? 251 VAL A N   1 
ATOM   4116 C  CA  . VAL B 2 255 ? 1.482   -43.243 1.819   1   47.65  ? 251 VAL A CA  1 
ATOM   4117 C  C   . VAL B 2 255 ? 1.081   -43.354 3.285   1   50.58  ? 251 VAL A C   1 
ATOM   4118 O  O   . VAL B 2 255 ? 1.682   -42.683 4.122   1   52.11  ? 251 VAL A O   1 
ATOM   4119 C  CB  . VAL B 2 255 ? 0.58    -42.253 1.061   1   45.15  ? 251 VAL A CB  1 
ATOM   4120 C  CG1 . VAL B 2 255 ? 0.564   -40.857 1.674   1   43.48  ? 251 VAL A CG1 1 
ATOM   4121 C  CG2 . VAL B 2 255 ? 0.99    -42.187 -0.398  1   45.32  ? 251 VAL A CG2 1 
ATOM   4122 N  N   . VAL B 2 256 ? 0.064   -44.185 3.578   1   49.73  ? 252 VAL A N   1 
ATOM   4123 C  CA  . VAL B 2 256 ? -0.453  -44.33  4.927   1   44.6   ? 252 VAL A CA  1 
ATOM   4124 C  C   . VAL B 2 256 ? -0.851  -45.784 5.113   1   46.4   ? 252 VAL A C   1 
ATOM   4125 O  O   . VAL B 2 256 ? -2.036  -46.139 5.099   1   47.27  ? 252 VAL A O   1 
ATOM   4126 C  CB  . VAL B 2 256 ? -1.602  -43.339 5.196   1   45.43  ? 252 VAL A CB  1 
ATOM   4127 C  CG1 . VAL B 2 256 ? -2.168  -43.471 6.618   1   45.15  ? 252 VAL A CG1 1 
ATOM   4128 C  CG2 . VAL B 2 256 ? -1.164  -41.894 4.903   1   40.74  ? 252 VAL A CG2 1 
ATOM   4129 N  N   . PRO B 2 257 ? 0.16    -46.673 5.254   1   46.64  ? 253 PRO A N   1 
ATOM   4130 C  CA  . PRO B 2 257 ? -0.068  -48.118 5.328   1   45.61  ? 253 PRO A CA  1 
ATOM   4131 C  C   . PRO B 2 257 ? -1.228  -48.585 6.199   1   46.53  ? 253 PRO A C   1 
ATOM   4132 O  O   . PRO B 2 257 ? -1.973  -49.449 5.784   1   49.7   ? 253 PRO A O   1 
ATOM   4133 C  CB  . PRO B 2 257 ? 1.276   -48.675 5.805   1   45.08  ? 253 PRO A CB  1 
ATOM   4134 C  CG  . PRO B 2 257 ? 2.274   -47.678 5.282   1   43.91  ? 253 PRO A CG  1 
ATOM   4135 C  CD  . PRO B 2 257 ? 1.586   -46.325 5.333   1   43.58  ? 253 PRO A CD  1 
ATOM   4136 N  N   . PRO B 2 258 ? -1.431  -48.091 7.439   1   49.03  ? 254 PRO A N   1 
ATOM   4137 C  CA  . PRO B 2 258 ? -2.508  -48.616 8.294   1   50.98  ? 254 PRO A CA  1 
ATOM   4138 C  C   . PRO B 2 258 ? -3.926  -48.404 7.763   1   50.99  ? 254 PRO A C   1 
ATOM   4139 O  O   . PRO B 2 258 ? -4.818  -49.179 8.085   1   57.67  ? 254 PRO A O   1 
ATOM   4140 C  CB  . PRO B 2 258 ? -2.335  -47.902 9.642   1   49.03  ? 254 PRO A CB  1 
ATOM   4141 C  CG  . PRO B 2 258 ? -0.979  -47.24  9.547   1   48.35  ? 254 PRO A CG  1 
ATOM   4142 C  CD  . PRO B 2 258 ? -0.674  -47.011 8.087   1   47.27  ? 254 PRO A CD  1 
ATOM   4143 N  N   . LEU B 2 259 ? -4.119  -47.353 6.956   1   48.06  ? 255 LEU A N   1 
ATOM   4144 C  CA  . LEU B 2 259 ? -5.428  -46.927 6.476   1   45.11  ? 255 LEU A CA  1 
ATOM   4145 C  C   . LEU B 2 259 ? -6.04   -47.973 5.544   1   47.28  ? 255 LEU A C   1 
ATOM   4146 O  O   . LEU B 2 259 ? -5.324  -48.582 4.759   1   49.51  ? 255 LEU A O   1 
ATOM   4147 C  CB  . LEU B 2 259 ? -5.171  -45.621 5.745   1   39.96  ? 255 LEU A CB  1 
ATOM   4148 C  CG  . LEU B 2 259 ? -6.307  -44.613 5.802   1   40.36  ? 255 LEU A CG  1 
ATOM   4149 C  CD1 . LEU B 2 259 ? -6.812  -44.401 7.212   1   39.48  ? 255 LEU A CD1 1 
ATOM   4150 C  CD2 . LEU B 2 259 ? -5.852  -43.298 5.19    1   41.88  ? 255 LEU A CD2 1 
ATOM   4151 N  N   A ASP B 2 260 ? -7.349  -48.222 5.648   0.5 48.96  ? 256 ASP A N   1 
ATOM   4152 N  N   B ASP B 2 260 ? -7.378  -48.096 5.638   0.5 47.81  ? 256 ASP A N   1 
ATOM   4153 C  CA  A ASP B 2 260 ? -7.982  -49.223 4.796   0.5 50.49  ? 256 ASP A CA  1 
ATOM   4154 C  CA  B ASP B 2 260 ? -8.244  -49.061 4.957   0.5 48.77  ? 256 ASP A CA  1 
ATOM   4155 C  C   A ASP B 2 260 ? -8.664  -48.561 3.601   0.5 49.38  ? 256 ASP A C   1 
ATOM   4156 C  C   B ASP B 2 260 ? -8.618  -48.548 3.561   0.5 48.37  ? 256 ASP A C   1 
ATOM   4157 O  O   A ASP B 2 260 ? -8.662  -47.339 3.491   0.5 48.13  ? 256 ASP A O   1 
ATOM   4158 O  O   B ASP B 2 260 ? -8.334  -47.399 3.235   0.5 47.43  ? 256 ASP A O   1 
ATOM   4159 C  CB  A ASP B 2 260 ? -8.847  -50.195 5.582   0.5 52.27  ? 256 ASP A CB  1 
ATOM   4160 C  CB  B ASP B 2 260 ? -9.479  -49.363 5.807   0.5 47.8   ? 256 ASP A CB  1 
ATOM   4161 C  CG  A ASP B 2 260 ? -8.1    -51.451 5.992   0.5 56.23  ? 256 ASP A CG  1 
ATOM   4162 C  CG  B ASP B 2 260 ? -10.314 -48.159 6.248   0.5 44.52  ? 256 ASP A CG  1 
ATOM   4163 O  OD1 A ASP B 2 260 ? -7.411  -51.423 7.039   0.5 54.08  ? 256 ASP A OD1 1 
ATOM   4164 O  OD1 B ASP B 2 260 ? -11.153 -47.687 5.452   0.5 41.66  ? 256 ASP A OD1 1 
ATOM   4165 O  OD2 A ASP B 2 260 ? -8.161  -52.417 5.207   0.5 60.62  ? 256 ASP A OD2 1 
ATOM   4166 O  OD2 B ASP B 2 260 ? -10.085 -47.666 7.374   0.5 43.65  ? 256 ASP A OD2 1 
ATOM   4167 N  N   . GLU B 2 261 ? -9.274  -49.385 2.74    1   50.59  ? 257 GLU A N   1 
ATOM   4168 C  CA  . GLU B 2 261 ? -9.741  -48.97  1.418   1   52.06  ? 257 GLU A CA  1 
ATOM   4169 C  C   . GLU B 2 261 ? -10.579 -47.672 1.422   1   51.38  ? 257 GLU A C   1 
ATOM   4170 O  O   . GLU B 2 261 ? -10.352 -46.788 0.593   1   49.52  ? 257 GLU A O   1 
ATOM   4171 C  CB  . GLU B 2 261 ? -10.438 -50.145 0.739   1   55.81  ? 257 GLU A CB  1 
ATOM   4172 C  CG  . GLU B 2 261 ? -10.775 -49.876 -0.726  1   63.86  ? 257 GLU A CG  1 
ATOM   4173 C  CD  . GLU B 2 261 ? -11.467 -51.05  -1.404  1   79.71  ? 257 GLU A CD  1 
ATOM   4174 O  OE1 . GLU B 2 261 ? -12.715 -51.004 -1.573  1   88.74  ? 257 GLU A OE1 1 
ATOM   4175 O  OE2 . GLU B 2 261 ? -10.756 -52.022 -1.754  1   85.26  ? 257 GLU A OE2 1 
ATOM   4176 N  N   . ASP B 2 262 ? -11.523 -47.518 2.367   1   48.62  ? 258 ASP A N   1 
ATOM   4177 C  CA  . ASP B 2 262 ? -12.379 -46.338 2.434   1   45.96  ? 258 ASP A CA  1 
ATOM   4178 C  C   . ASP B 2 262 ? -11.55  -45.125 2.845   1   45.59  ? 258 ASP A C   1 
ATOM   4179 O  O   . ASP B 2 262 ? -11.641 -44.058 2.23    1   42.13  ? 258 ASP A O   1 
ATOM   4180 C  CB  . ASP B 2 262 ? -13.57  -46.571 3.357   1   47.53  ? 258 ASP A CB  1 
ATOM   4181 C  CG  . ASP B 2 262 ? -14.669 -47.496 2.821   1   53.76  ? 258 ASP A CG  1 
ATOM   4182 O  OD1 . ASP B 2 262 ? -14.719 -47.707 1.591   1   52.62  ? 258 ASP A OD1 1 
ATOM   4183 O  OD2 . ASP B 2 262 ? -15.48  -48.024 3.628   1   54.06  ? 258 ASP A OD2 1 
ATOM   4184 N  N   . GLY B 2 263 ? -10.766 -45.289 3.924   1   44.58  ? 259 GLY A N   1 
ATOM   4185 C  CA  . GLY B 2 263 ? -9.818  -44.278 4.347   1   42.59  ? 259 GLY A CA  1 
ATOM   4186 C  C   . GLY B 2 263 ? -9.005  -43.734 3.171   1   43.71  ? 259 GLY A C   1 
ATOM   4187 O  O   . GLY B 2 263 ? -8.997  -42.515 2.952   1   42.35  ? 259 GLY A O   1 
ATOM   4188 N  N   . ARG B 2 264 ? -8.359  -44.641 2.409   1   41.84  ? 260 ARG A N   1 
ATOM   4189 C  CA  . ARG B 2 264 ? -7.475  -44.278 1.308   1   43.03  ? 260 ARG A CA  1 
ATOM   4190 C  C   . ARG B 2 264 ? -8.241  -43.498 0.237   1   42.32  ? 260 ARG A C   1 
ATOM   4191 O  O   . ARG B 2 264 ? -7.761  -42.48  -0.269  1   42.64  ? 260 ARG A O   1 
ATOM   4192 C  CB  . ARG B 2 264 ? -6.871  -45.514 0.632   1   44.8   ? 260 ARG A CB  1 
ATOM   4193 C  CG  . ARG B 2 264 ? -5.816  -46.199 1.479   1   47.32  ? 260 ARG A CG  1 
ATOM   4194 C  CD  . ARG B 2 264 ? -4.792  -47.051 0.725   1   46.87  ? 260 ARG A CD  1 
ATOM   4195 N  NE  . ARG B 2 264 ? -5.398  -48.216 0.082   1   48.97  ? 260 ARG A NE  1 
ATOM   4196 C  CZ  . ARG B 2 264 ? -5.869  -49.293 0.709   1   51.19  ? 260 ARG A CZ  1 
ATOM   4197 N  NH1 . ARG B 2 264 ? -5.693  -49.458 2.015   1   53.3   ? 260 ARG A NH1 1 
ATOM   4198 N  NH2 . ARG B 2 264 ? -6.529  -50.196 0.02    1   48.3   ? 260 ARG A NH2 1 
ATOM   4199 N  N   . SER B 2 265 ? -9.407  -44.029 -0.134  1   42.07  ? 261 SER A N   1 
ATOM   4200 C  CA  . SER B 2 265 ? -10.262 -43.399 -1.115  1   41.06  ? 261 SER A CA  1 
ATOM   4201 C  C   . SER B 2 265 ? -10.467 -41.943 -0.688  1   41.48  ? 261 SER A C   1 
ATOM   4202 O  O   . SER B 2 265 ? -10.24  -41.005 -1.472  1   38.97  ? 261 SER A O   1 
ATOM   4203 C  CB  . SER B 2 265 ? -11.554 -44.173 -1.224  1   40.82  ? 261 SER A CB  1 
ATOM   4204 O  OG  . SER B 2 265 ? -12.572 -43.456 -1.914  1   42.78  ? 261 SER A OG  1 
ATOM   4205 N  N   . LEU B 2 266 ? -10.811 -41.773 0.598   1   37.52  ? 262 LEU A N   1 
ATOM   4206 C  CA  . LEU B 2 266 ? -11.225 -40.464 1.05    1   38.3   ? 262 LEU A CA  1 
ATOM   4207 C  C   . LEU B 2 266 ? -10.007 -39.544 1.069   1   40.04  ? 262 LEU A C   1 
ATOM   4208 O  O   . LEU B 2 266 ? -10.097 -38.414 0.577   1   41.64  ? 262 LEU A O   1 
ATOM   4209 C  CB  . LEU B 2 266 ? -11.986 -40.514 2.382   1   38.56  ? 262 LEU A CB  1 
ATOM   4210 C  CG  . LEU B 2 266 ? -12.149 -39.171 3.109   1   38.54  ? 262 LEU A CG  1 
ATOM   4211 C  CD1 . LEU B 2 266 ? -12.952 -38.139 2.278   1   35.74  ? 262 LEU A CD1 1 
ATOM   4212 C  CD2 . LEU B 2 266 ? -12.774 -39.393 4.474   1   37.17  ? 262 LEU A CD2 1 
ATOM   4213 N  N   . LEU B 2 267 ? -8.881  -40.05  1.599   1   37.09  ? 263 LEU A N   1 
ATOM   4214 C  CA  . LEU B 2 267 ? -7.659  -39.264 1.711   1   37.94  ? 263 LEU A CA  1 
ATOM   4215 C  C   . LEU B 2 267 ? -7.186  -38.84  0.329   1   40.86  ? 263 LEU A C   1 
ATOM   4216 O  O   . LEU B 2 267 ? -6.753  -37.698 0.15    1   42.69  ? 263 LEU A O   1 
ATOM   4217 C  CB  . LEU B 2 267 ? -6.557  -40.05  2.424   1   43     ? 263 LEU A CB  1 
ATOM   4218 C  CG  . LEU B 2 267 ? -5.199  -39.353 2.574   1   41.98  ? 263 LEU A CG  1 
ATOM   4219 C  CD1 . LEU B 2 267 ? -5.305  -38.061 3.347   1   37.85  ? 263 LEU A CD1 1 
ATOM   4220 C  CD2 . LEU B 2 267 ? -4.211  -40.264 3.271   1   44.29  ? 263 LEU A CD2 1 
ATOM   4221 N  N   . SER B 2 268 ? -7.253  -39.781 -0.628  1   41.3   ? 264 SER A N   1 
ATOM   4222 C  CA  . SER B 2 268 ? -6.817  -39.504 -1.99   1   42.59  ? 264 SER A CA  1 
ATOM   4223 C  C   . SER B 2 268 ? -7.66   -38.378 -2.589  1   39.23  ? 264 SER A C   1 
ATOM   4224 O  O   . SER B 2 268 ? -7.167  -37.594 -3.392  1   42.36  ? 264 SER A O   1 
ATOM   4225 C  CB  . SER B 2 268 ? -6.824  -40.742 -2.876  1   43.43  ? 264 SER A CB  1 
ATOM   4226 O  OG  . SER B 2 268 ? -8.165  -41.151 -3.126  1   51.8   ? 264 SER A OG  1 
ATOM   4227 N  N   . GLN B 2 269 ? -8.928  -38.289 -2.206  1   35.55  ? 265 GLN A N   1 
ATOM   4228 C  CA  . GLN B 2 269 ? -9.739  -37.282 -2.85   1   37.64  ? 265 GLN A CA  1 
ATOM   4229 C  C   . GLN B 2 269 ? -9.539  -35.943 -2.152  1   38.26  ? 265 GLN A C   1 
ATOM   4230 O  O   . GLN B 2 269 ? -9.795  -34.894 -2.748  1   40.49  ? 265 GLN A O   1 
ATOM   4231 C  CB  . GLN B 2 269 ? -11.195 -37.702 -2.832  1   39.44  ? 265 GLN A CB  1 
ATOM   4232 C  CG  . GLN B 2 269 ? -11.417 -38.952 -3.651  1   43.78  ? 265 GLN A CG  1 
ATOM   4233 C  CD  . GLN B 2 269 ? -12.845 -39.417 -3.528  1   48.17  ? 265 GLN A CD  1 
ATOM   4234 O  OE1 . GLN B 2 269 ? -13.118 -40.492 -2.982  1   51.57  ? 265 GLN A OE1 1 
ATOM   4235 N  NE2 . GLN B 2 269 ? -13.77  -38.586 -3.993  1   48.64  ? 265 GLN A NE2 1 
ATOM   4236 N  N   . MET B 2 270 ? -9.043  -35.981 -0.913  1   35.19  ? 266 MET A N   1 
ATOM   4237 C  CA  . MET B 2 270 ? -8.691  -34.741 -0.249  1   37.53  ? 266 MET A CA  1 
ATOM   4238 C  C   . MET B 2 270 ? -7.389  -34.153 -0.808  1   42.82  ? 266 MET A C   1 
ATOM   4239 O  O   . MET B 2 270 ? -7.258  -32.921 -0.846  1   45.26  ? 266 MET A O   1 
ATOM   4240 C  CB  . MET B 2 270 ? -8.638  -34.907 1.266   1   34.38  ? 266 MET A CB  1 
ATOM   4241 C  CG  . MET B 2 270 ? -9.997  -35.221 1.825   1   36.17  ? 266 MET A CG  1 
ATOM   4242 S  SD  . MET B 2 270 ? -10.056 -35.63  3.588   1   40.55  ? 266 MET A SD  1 
ATOM   4243 C  CE  . MET B 2 270 ? -9.952  -33.965 4.268   1   31.06  ? 266 MET A CE  1 
ATOM   4244 N  N   . LEU B 2 271 ? -6.476  -35.017 -1.293  1   40.2   ? 267 LEU A N   1 
ATOM   4245 C  CA  . LEU B 2 271 ? -5.146  -34.602 -1.731  1   42.13  ? 267 LEU A CA  1 
ATOM   4246 C  C   . LEU B 2 271 ? -5.034  -34.675 -3.255  1   42.77  ? 267 LEU A C   1 
ATOM   4247 O  O   . LEU B 2 271 ? -3.947  -34.889 -3.8    1   44.26  ? 267 LEU A O   1 
ATOM   4248 C  CB  . LEU B 2 271 ? -4.077  -35.483 -1.076  1   38.98  ? 267 LEU A CB  1 
ATOM   4249 C  CG  . LEU B 2 271 ? -4.061  -35.565 0.448   1   38.96  ? 267 LEU A CG  1 
ATOM   4250 C  CD1 . LEU B 2 271 ? -3.112  -36.646 0.911   1   39.75  ? 267 LEU A CD1 1 
ATOM   4251 C  CD2 . LEU B 2 271 ? -3.674  -34.233 1.043   1   40.5   ? 267 LEU A CD2 1 
ATOM   4252 N  N   . HIS B 2 272 ? -6.161  -34.548 -3.947  1   40.37  ? 268 HIS A N   1 
ATOM   4253 C  CA  . HIS B 2 272 ? -6.131  -34.46  -5.403  1   43.28  ? 268 HIS A CA  1 
ATOM   4254 C  C   . HIS B 2 272 ? -5.393  -33.177 -5.802  1   43.78  ? 268 HIS A C   1 
ATOM   4255 O  O   . HIS B 2 272 ? -5.636  -32.104 -5.217  1   41.93  ? 268 HIS A O   1 
ATOM   4256 C  CB  . HIS B 2 272 ? -7.565  -34.463 -5.962  1   45.73  ? 268 HIS A CB  1 
ATOM   4257 C  CG  . HIS B 2 272 ? -7.595  -34.81  -7.404  1   59.25  ? 268 HIS A CG  1 
ATOM   4258 N  ND1 . HIS B 2 272 ? -8.281  -35.891 -7.904  1   64.12  ? 268 HIS A ND1 1 
ATOM   4259 C  CD2 . HIS B 2 272 ? -6.928  -34.275 -8.464  1   69.32  ? 268 HIS A CD2 1 
ATOM   4260 C  CE1 . HIS B 2 272 ? -8.093  -35.96  -9.222  1   67.18  ? 268 HIS A CE1 1 
ATOM   4261 N  NE2 . HIS B 2 272 ? -7.261  -34.996 -9.578  1   67.68  ? 268 HIS A NE2 1 
ATOM   4262 N  N   . TYR B 2 273 ? -4.49   -33.284 -6.79   1   41.44  ? 269 TYR A N   1 
ATOM   4263 C  CA  . TYR B 2 273 ? -3.724  -32.119 -7.204  1   40.89  ? 269 TYR A CA  1 
ATOM   4264 C  C   . TYR B 2 273 ? -4.651  -30.999 -7.672  1   39.34  ? 269 TYR A C   1 
ATOM   4265 O  O   . TYR B 2 273 ? -4.484  -29.839 -7.266  1   39.51  ? 269 TYR A O   1 
ATOM   4266 C  CB  . TYR B 2 273 ? -2.68   -32.377 -8.292  1   37.25  ? 269 TYR A CB  1 
ATOM   4267 C  CG  . TYR B 2 273 ? -1.372  -32.884 -7.737  1   39.22  ? 269 TYR A CG  1 
ATOM   4268 C  CD1 . TYR B 2 273 ? -0.503  -32.022 -7.082  1   40.61  ? 269 TYR A CD1 1 
ATOM   4269 C  CD2 . TYR B 2 273 ? -1.008  -34.214 -7.865  1   42.27  ? 269 TYR A CD2 1 
ATOM   4270 C  CE1 . TYR B 2 273 ? 0.698   -32.474 -6.566  1   40.74  ? 269 TYR A CE1 1 
ATOM   4271 C  CE2 . TYR B 2 273 ? 0.193   -34.684 -7.349  1   43.88  ? 269 TYR A CE2 1 
ATOM   4272 C  CZ  . TYR B 2 273 ? 1.051   -33.807 -6.709  1   42.88  ? 269 TYR A CZ  1 
ATOM   4273 O  OH  . TYR B 2 273 ? 2.235   -34.271 -6.216  1   42.81  ? 269 TYR A OH  1 
ATOM   4274 N  N   . ASP B 2 274 ? -5.562  -31.365 -8.583  1   37.08  ? 270 ASP A N   1 
ATOM   4275 C  CA  . ASP B 2 274 ? -6.399  -30.409 -9.291  1   39.98  ? 270 ASP A CA  1 
ATOM   4276 C  C   . ASP B 2 274 ? -7.428  -29.839 -8.326  1   41.41  ? 270 ASP A C   1 
ATOM   4277 O  O   . ASP B 2 274 ? -8.297  -30.569 -7.856  1   45.89  ? 270 ASP A O   1 
ATOM   4278 C  CB  . ASP B 2 274 ? -7.166  -31.087 -10.415 1   41.34  ? 270 ASP A CB  1 
ATOM   4279 C  CG  . ASP B 2 274 ? -7.882  -30.113 -11.329 1   43.1   ? 270 ASP A CG  1 
ATOM   4280 O  OD1 . ASP B 2 274 ? -7.929  -28.92  -10.968 1   45.98  ? 270 ASP A OD1 1 
ATOM   4281 O  OD2 . ASP B 2 274 ? -8.326  -30.541 -12.407 1   44.28  ? 270 ASP A OD2 1 
ATOM   4282 N  N   . PRO B 2 275 ? -7.383  -28.537 -7.969  1   42.07  ? 271 PRO A N   1 
ATOM   4283 C  CA  . PRO B 2 275 ? -8.306  -27.992 -6.97   1   39.14  ? 271 PRO A CA  1 
ATOM   4284 C  C   . PRO B 2 275 ? -9.763  -28.147 -7.395  1   40.48  ? 271 PRO A C   1 
ATOM   4285 O  O   . PRO B 2 275 ? -10.637 -28.234 -6.528  1   41.95  ? 271 PRO A O   1 
ATOM   4286 C  CB  . PRO B 2 275 ? -7.871  -26.526 -6.859  1   36.75  ? 271 PRO A CB  1 
ATOM   4287 C  CG  . PRO B 2 275 ? -6.445  -26.577 -7.251  1   38.99  ? 271 PRO A CG  1 
ATOM   4288 C  CD  . PRO B 2 275 ? -6.436  -27.532 -8.458  1   40.83  ? 271 PRO A CD  1 
ATOM   4289 N  N   . ASN B 2 276 ? -10.003 -28.231 -8.716  1   40.2   ? 272 ASN A N   1 
ATOM   4290 C  CA  . ASN B 2 276 ? -11.344 -28.45  -9.249  1   44.82  ? 272 ASN A CA  1 
ATOM   4291 C  C   . ASN B 2 276 ? -11.884 -29.851 -8.953  1   45.47  ? 272 ASN A C   1 
ATOM   4292 O  O   . ASN B 2 276 ? -13.099 -30.001 -8.909  1   49.24  ? 272 ASN A O   1 
ATOM   4293 C  CB  . ASN B 2 276 ? -11.45  -28.198 -10.744 1   44.13  ? 272 ASN A CB  1 
ATOM   4294 C  CG  . ASN B 2 276 ? -11.137 -26.77  -11.113 1   49.21  ? 272 ASN A CG  1 
ATOM   4295 O  OD1 . ASN B 2 276 ? -11.575 -25.824 -10.446 1   48.01  ? 272 ASN A OD1 1 
ATOM   4296 N  ND2 . ASN B 2 276 ? -10.337 -26.596 -12.154 1   54.02  ? 272 ASN A ND2 1 
ATOM   4297 N  N   . LYS B 2 277 ? -11.008 -30.856 -8.775  1   45.85  ? 273 LYS A N   1 
ATOM   4298 C  CA  . LYS B 2 277 ? -11.405 -32.248 -8.596  1   45.74  ? 273 LYS A CA  1 
ATOM   4299 C  C   . LYS B 2 277 ? -11.32  -32.641 -7.122  1   42.88  ? 273 LYS A C   1 
ATOM   4300 O  O   . LYS B 2 277 ? -11.8   -33.706 -6.719  1   41.62  ? 273 LYS A O   1 
ATOM   4301 C  CB  . LYS B 2 277 ? -10.428 -33.207 -9.289  1   49.41  ? 273 LYS A CB  1 
ATOM   4302 C  CG  . LYS B 2 277 ? -10.142 -32.965 -10.748 1   57.32  ? 273 LYS A CG  1 
ATOM   4303 C  CD  . LYS B 2 277 ? -11.241 -33.534 -11.632 1   72.54  ? 273 LYS A CD  1 
ATOM   4304 C  CE  . LYS B 2 277 ? -10.688 -34.3   -12.803 1   78.11  ? 273 LYS A CE  1 
ATOM   4305 N  NZ  . LYS B 2 277 ? -11.718 -35.165 -13.382 1   76.74  ? 273 LYS A NZ  1 
ATOM   4306 N  N   . ARG B 2 278 ? -10.629 -31.823 -6.321  1   41.01  ? 274 ARG A N   1 
ATOM   4307 C  CA  . ARG B 2 278 ? -10.487 -32.149 -4.907  1   39.13  ? 274 ARG A CA  1 
ATOM   4308 C  C   . ARG B 2 278 ? -11.874 -32.175 -4.237  1   40.15  ? 274 ARG A C   1 
ATOM   4309 O  O   . ARG B 2 278 ? -12.755 -31.364 -4.549  1   36.35  ? 274 ARG A O   1 
ATOM   4310 C  CB  . ARG B 2 278 ? -9.551  -31.085 -4.339  1   39.22  ? 274 ARG A CB  1 
ATOM   4311 C  CG  . ARG B 2 278 ? -8.785  -31.563 -3.116  1   42.95  ? 274 ARG A CG  1 
ATOM   4312 C  CD  . ARG B 2 278 ? -7.794  -30.503 -2.633  1   40.93  ? 274 ARG A CD  1 
ATOM   4313 N  NE  . ARG B 2 278 ? -6.716  -30.215 -3.586  1   40.43  ? 274 ARG A NE  1 
ATOM   4314 C  CZ  . ARG B 2 278 ? -6.06   -29.056 -3.573  1   39.12  ? 274 ARG A CZ  1 
ATOM   4315 N  NH1 . ARG B 2 278 ? -6.413  -28.114 -2.706  1   35.93  ? 274 ARG A NH1 1 
ATOM   4316 N  NH2 . ARG B 2 278 ? -5.098  -28.839 -4.454  1   36.7   ? 274 ARG A NH2 1 
ATOM   4317 N  N   . ILE B 2 279 ? -12.079 -33.123 -3.315  1   36.73  ? 275 ILE A N   1 
ATOM   4318 C  CA  . ILE B 2 279 ? -13.396 -33.322 -2.741  1   34.16  ? 275 ILE A CA  1 
ATOM   4319 C  C   . ILE B 2 279 ? -13.76  -32.106 -1.886  1   34.77  ? 275 ILE A C   1 
ATOM   4320 O  O   . ILE B 2 279 ? -12.893 -31.503 -1.275  1   34.48  ? 275 ILE A O   1 
ATOM   4321 C  CB  . ILE B 2 279 ? -13.457 -34.662 -1.992  1   34.39  ? 275 ILE A CB  1 
ATOM   4322 C  CG1 . ILE B 2 279 ? -14.898 -34.988 -1.586  1   35.94  ? 275 ILE A CG1 1 
ATOM   4323 C  CG2 . ILE B 2 279 ? -12.516 -34.669 -0.785  1   32.65  ? 275 ILE A CG2 1 
ATOM   4324 C  CD1 . ILE B 2 279 ? -15.163 -36.441 -1.222  1   35.31  ? 275 ILE A CD1 1 
ATOM   4325 N  N   . SER B 2 280 ? -15.044 -31.71  -1.863  1   36.78  ? 276 SER A N   1 
ATOM   4326 C  CA  . SER B 2 280 ? -15.491 -30.606 -1.016  1   37.32  ? 276 SER A CA  1 
ATOM   4327 C  C   . SER B 2 280 ? -15.864 -31.148 0.366   1   42.25  ? 276 SER A C   1 
ATOM   4328 O  O   . SER B 2 280 ? -16.235 -32.311 0.478   1   42.54  ? 276 SER A O   1 
ATOM   4329 C  CB  . SER B 2 280 ? -16.679 -29.943 -1.604  1   37.29  ? 276 SER A CB  1 
ATOM   4330 O  OG  . SER B 2 280 ? -17.832 -30.748 -1.398  1   35.33  ? 276 SER A OG  1 
ATOM   4331 N  N   . ALA B 2 281 ? -15.811 -30.313 1.426   1   43.77  ? 277 ALA A N   1 
ATOM   4332 C  CA  . ALA B 2 281 ? -16.214 -30.786 2.746   1   37.52  ? 277 ALA A CA  1 
ATOM   4333 C  C   . ALA B 2 281 ? -17.65  -31.326 2.732   1   39.63  ? 277 ALA A C   1 
ATOM   4334 O  O   . ALA B 2 281 ? -17.919 -32.379 3.289   1   45.88  ? 277 ALA A O   1 
ATOM   4335 C  CB  . ALA B 2 281 ? -16.04  -29.706 3.755   1   36     ? 277 ALA A CB  1 
ATOM   4336 N  N   . LYS B 2 282 ? -18.571 -30.638 2.056   1   38.41  ? 278 LYS A N   1 
ATOM   4337 C  CA  . LYS B 2 282 ? -19.965 -31.049 1.983   1   37.35  ? 278 LYS A CA  1 
ATOM   4338 C  C   . LYS B 2 282 ? -20.099 -32.451 1.376   1   38.37  ? 278 LYS A C   1 
ATOM   4339 O  O   . LYS B 2 282 ? -20.794 -33.302 1.914   1   38.29  ? 278 LYS A O   1 
ATOM   4340 C  CB  . LYS B 2 282 ? -20.695 -29.89  1.296   1   37.8   ? 278 LYS A CB  1 
ATOM   4341 C  CG  . LYS B 2 282 ? -22.026 -30.174 0.67    1   41.62  ? 278 LYS A CG  1 
ATOM   4342 C  CD  . LYS B 2 282 ? -22.585 -28.935 -0.029  1   44.86  ? 278 LYS A CD  1 
ATOM   4343 C  CE  . LYS B 2 282 ? -23.027 -27.866 0.924   1   46.89  ? 278 LYS A CE  1 
ATOM   4344 N  NZ  . LYS B 2 282 ? -23.799 -26.808 0.264   1   42.82  ? 278 LYS A NZ  1 
ATOM   4345 N  N   . ALA B 2 283 ? -19.369 -32.741 0.296   1   44.02  ? 279 ALA A N   1 
ATOM   4346 C  CA  . ALA B 2 283 ? -19.397 -34.07  -0.337  1   47.02  ? 279 ALA A CA  1 
ATOM   4347 C  C   . ALA B 2 283 ? -18.792 -35.144 0.575   1   45.42  ? 279 ALA A C   1 
ATOM   4348 O  O   . ALA B 2 283 ? -19.297 -36.265 0.655   1   48.38  ? 279 ALA A O   1 
ATOM   4349 C  CB  . ALA B 2 283 ? -18.664 -34.055 -1.676  1   40.97  ? 279 ALA A CB  1 
ATOM   4350 N  N   . ALA B 2 284 ? -17.714 -34.768 1.271   1   38.64  ? 280 ALA A N   1 
ATOM   4351 C  CA  . ALA B 2 284 ? -16.885 -35.711 1.979   1   38.64  ? 280 ALA A CA  1 
ATOM   4352 C  C   . ALA B 2 284 ? -17.671 -36.306 3.137   1   39.32  ? 280 ALA A C   1 
ATOM   4353 O  O   . ALA B 2 284 ? -17.481 -37.475 3.465   1   43.45  ? 280 ALA A O   1 
ATOM   4354 C  CB  . ALA B 2 284 ? -15.613 -35.034 2.425   1   35.4   ? 280 ALA A CB  1 
ATOM   4355 N  N   . LEU B 2 285 ? -18.594 -35.52  3.701   1   38.78  ? 281 LEU A N   1 
ATOM   4356 C  CA  . LEU B 2 285 ? -19.478 -35.978 4.769   1   40.03  ? 281 LEU A CA  1 
ATOM   4357 C  C   . LEU B 2 285 ? -20.222 -37.267 4.419   1   42.62  ? 281 LEU A C   1 
ATOM   4358 O  O   . LEU B 2 285 ? -20.599 -38.001 5.332   1   46.94  ? 281 LEU A O   1 
ATOM   4359 C  CB  . LEU B 2 285 ? -20.457 -34.869 5.136   1   42.58  ? 281 LEU A CB  1 
ATOM   4360 C  CG  . LEU B 2 285 ? -19.854 -33.699 5.915   1   41.91  ? 281 LEU A CG  1 
ATOM   4361 C  CD1 . LEU B 2 285 ? -20.924 -32.669 6.189   1   40.82  ? 281 LEU A CD1 1 
ATOM   4362 C  CD2 . LEU B 2 285 ? -19.284 -34.201 7.234   1   38.63  ? 281 LEU A CD2 1 
ATOM   4363 N  N   . ALA B 2 286 ? -20.421 -37.54  3.119   1   40.27  ? 282 ALA A N   1 
ATOM   4364 C  CA  . ALA B 2 286 ? -21.135 -38.721 2.671   1   39.43  ? 282 ALA A CA  1 
ATOM   4365 C  C   . ALA B 2 286 ? -20.193 -39.863 2.269   1   39.93  ? 282 ALA A C   1 
ATOM   4366 O  O   . ALA B 2 286 ? -20.636 -40.912 1.79    1   42.35  ? 282 ALA A O   1 
ATOM   4367 C  CB  . ALA B 2 286 ? -22.009 -38.343 1.496   1   40.67  ? 282 ALA A CB  1 
ATOM   4368 N  N   . HIS B 2 287 ? -18.884 -39.677 2.412   1   38.73  ? 283 HIS A N   1 
ATOM   4369 C  CA  . HIS B 2 287 ? -17.986 -40.752 2.012   1   40.09  ? 283 HIS A CA  1 
ATOM   4370 C  C   . HIS B 2 287 ? -18.27  -42.012 2.838   1   40.08  ? 283 HIS A C   1 
ATOM   4371 O  O   . HIS B 2 287 ? -18.523 -41.946 4.042   1   40.75  ? 283 HIS A O   1 
ATOM   4372 C  CB  . HIS B 2 287 ? -16.533 -40.272 2.078   1   37.01  ? 283 HIS A CB  1 
ATOM   4373 C  CG  . HIS B 2 287 ? -15.584 -41.138 1.344   1   38.49  ? 283 HIS A CG  1 
ATOM   4374 N  ND1 . HIS B 2 287 ? -15.238 -42.408 1.76    1   40.52  ? 283 HIS A ND1 1 
ATOM   4375 C  CD2 . HIS B 2 287 ? -14.892 -40.916 0.221   1   38.08  ? 283 HIS A CD2 1 
ATOM   4376 C  CE1 . HIS B 2 287 ? -14.375 -42.945 0.886   1   41.37  ? 283 HIS A CE1 1 
ATOM   4377 N  NE2 . HIS B 2 287 ? -14.159 -42.059 -0.072  1   38.38  ? 283 HIS A NE2 1 
ATOM   4378 N  N   . PRO B 2 288 ? -18.243 -43.211 2.225   1   41.14  ? 284 PRO A N   1 
ATOM   4379 C  CA  . PRO B 2 288 ? -18.42  -44.46  2.981   1   42.26  ? 284 PRO A CA  1 
ATOM   4380 C  C   . PRO B 2 288 ? -17.459 -44.705 4.156   1   42.43  ? 284 PRO A C   1 
ATOM   4381 O  O   . PRO B 2 288 ? -17.777 -45.494 5.064   1   42.29  ? 284 PRO A O   1 
ATOM   4382 C  CB  . PRO B 2 288 ? -18.443 -45.6   1.943   1   41.38  ? 284 PRO A CB  1 
ATOM   4383 C  CG  . PRO B 2 288 ? -18.101 -44.938 0.611   1   40.34  ? 284 PRO A CG  1 
ATOM   4384 C  CD  . PRO B 2 288 ? -18.028 -43.426 0.783   1   39.58  ? 284 PRO A CD  1 
ATOM   4385 N  N   . PHE B 2 289 ? -16.326 -43.975 4.192   1   39.56  ? 285 PHE A N   1 
ATOM   4386 C  CA  . PHE B 2 289 ? -15.432 -44.025 5.346   1   39.57  ? 285 PHE A CA  1 
ATOM   4387 C  C   . PHE B 2 289 ? -16.17  -43.767 6.669   1   40.12  ? 285 PHE A C   1 
ATOM   4388 O  O   . PHE B 2 289 ? -15.813 -44.314 7.718   1   41.19  ? 285 PHE A O   1 
ATOM   4389 C  CB  . PHE B 2 289 ? -14.313 -42.996 5.226   1   40.18  ? 285 PHE A CB  1 
ATOM   4390 C  CG  . PHE B 2 289 ? -13.307 -43.04  6.365   1   44.1   ? 285 PHE A CG  1 
ATOM   4391 C  CD1 . PHE B 2 289 ? -12.491 -44.162 6.561   1   47.12  ? 285 PHE A CD1 1 
ATOM   4392 C  CD2 . PHE B 2 289 ? -13.157 -41.961 7.228   1   44.81  ? 285 PHE A CD2 1 
ATOM   4393 C  CE1 . PHE B 2 289 ? -11.56  -44.21  7.586   1   42.84  ? 285 PHE A CE1 1 
ATOM   4394 C  CE2 . PHE B 2 289 ? -12.208 -42.011 8.247   1   45.01  ? 285 PHE A CE2 1 
ATOM   4395 C  CZ  . PHE B 2 289 ? -11.431 -43.138 8.433   1   43.45  ? 285 PHE A CZ  1 
ATOM   4396 N  N   . PHE B 2 290 ? -17.202 -42.922 6.635   1   38.38  ? 286 PHE A N   1 
ATOM   4397 C  CA  . PHE B 2 290 ? -17.911 -42.542 7.844   1   39.49  ? 286 PHE A CA  1 
ATOM   4398 C  C   . PHE B 2 290 ? -19.098 -43.459 8.164   1   44.47  ? 286 PHE A C   1 
ATOM   4399 O  O   . PHE B 2 290 ? -19.801 -43.19  9.144   1   48.55  ? 286 PHE A O   1 
ATOM   4400 C  CB  . PHE B 2 290 ? -18.329 -41.071 7.754   1   37.03  ? 286 PHE A CB  1 
ATOM   4401 C  CG  . PHE B 2 290 ? -17.15  -40.123 7.596   1   34.99  ? 286 PHE A CG  1 
ATOM   4402 C  CD1 . PHE B 2 290 ? -16.195 -40.003 8.602   1   34.87  ? 286 PHE A CD1 1 
ATOM   4403 C  CD2 . PHE B 2 290 ? -17.007 -39.346 6.449   1   33.54  ? 286 PHE A CD2 1 
ATOM   4404 C  CE1 . PHE B 2 290 ? -15.15  -39.101 8.47    1   34.87  ? 286 PHE A CE1 1 
ATOM   4405 C  CE2 . PHE B 2 290 ? -15.934 -38.475 6.314   1   32.55  ? 286 PHE A CE2 1 
ATOM   4406 C  CZ  . PHE B 2 290 ? -15.004 -38.35  7.32    1   32.85  ? 286 PHE A CZ  1 
ATOM   4407 N  N   . GLN B 2 291 ? -19.291 -44.558 7.411   1   46.7   ? 287 GLN A N   1 
ATOM   4408 C  CA  . GLN B 2 291 ? -20.497 -45.366 7.529   1   49.83  ? 287 GLN A CA  1 
ATOM   4409 C  C   . GLN B 2 291 ? -20.877 -45.705 8.977   1   54.18  ? 287 GLN A C   1 
ATOM   4410 O  O   . GLN B 2 291 ? -22.07  -45.782 9.282   1   61.56  ? 287 GLN A O   1 
ATOM   4411 C  CB  . GLN B 2 291 ? -20.56  -46.549 6.564   1   52.14  ? 287 GLN A CB  1 
ATOM   4412 C  CG  . GLN B 2 291 ? -19.723 -47.766 6.933   1   60.94  ? 287 GLN A CG  1 
ATOM   4413 C  CD  . GLN B 2 291 ? -19.634 -48.805 5.821   1   68     ? 287 GLN A CD  1 
ATOM   4414 O  OE1 . GLN B 2 291 ? -20.216 -49.896 5.908   1   76.95  ? 287 GLN A OE1 1 
ATOM   4415 N  NE2 . GLN B 2 291 ? -18.901 -48.495 4.754   1   58.04  ? 287 GLN A NE2 1 
ATOM   4416 N  N   A ASP B 2 292 ? -19.859 -45.854 9.848   0.5 51.76  ? 288 ASP A N   1 
ATOM   4417 N  N   B ASP B 2 292 ? -19.916 -45.978 9.872   0.5 53.67  ? 288 ASP A N   1 
ATOM   4418 C  CA  A ASP B 2 292 ? -20.022 -46.439 11.176  0.5 51.36  ? 288 ASP A CA  1 
ATOM   4419 C  CA  B ASP B 2 292 ? -20.348 -46.34  11.219  0.5 53.69  ? 288 ASP A CA  1 
ATOM   4420 C  C   A ASP B 2 292 ? -19.809 -45.416 12.295  0.5 51.29  ? 288 ASP A C   1 
ATOM   4421 C  C   B ASP B 2 292 ? -19.705 -45.425 12.254  0.5 52.8   ? 288 ASP A C   1 
ATOM   4422 O  O   A ASP B 2 292 ? -19.836 -45.8   13.462  0.5 50.65  ? 288 ASP A O   1 
ATOM   4423 O  O   B ASP B 2 292 ? -19.278 -45.885 13.309  0.5 52.51  ? 288 ASP A O   1 
ATOM   4424 C  CB  A ASP B 2 292 ? -19.139 -47.67  11.345  0.5 50.24  ? 288 ASP A CB  1 
ATOM   4425 C  CB  B ASP B 2 292 ? -20.327 -47.842 11.479  0.5 55.17  ? 288 ASP A CB  1 
ATOM   4426 C  CG  A ASP B 2 292 ? -17.713 -47.503 10.84   0.5 48.31  ? 288 ASP A CG  1 
ATOM   4427 C  CG  B ASP B 2 292 ? -21.516 -48.627 10.931  0.5 56.65  ? 288 ASP A CG  1 
ATOM   4428 O  OD1 A ASP B 2 292 ? -17.417 -46.428 10.258  0.5 44.5   ? 288 ASP A OD1 1 
ATOM   4429 O  OD1 B ASP B 2 292 ? -22.639 -48.497 11.485  0.5 55.13  ? 288 ASP A OD1 1 
ATOM   4430 O  OD2 A ASP B 2 292 ? -16.922 -48.45  11.016  0.5 48.13  ? 288 ASP A OD2 1 
ATOM   4431 O  OD2 B ASP B 2 292 ? -21.307 -49.359 9.941   0.5 55.96  ? 288 ASP A OD2 1 
ATOM   4432 N  N   . VAL B 2 293 ? -19.688 -44.122 11.941  1   52.12  ? 289 VAL A N   1 
ATOM   4433 C  CA  . VAL B 2 293 ? -19.137 -43.078 12.805  1   52.55  ? 289 VAL A CA  1 
ATOM   4434 C  C   . VAL B 2 293 ? -19.99  -42.814 14.052  1   58.74  ? 289 VAL A C   1 
ATOM   4435 O  O   . VAL B 2 293 ? -21.211 -43.044 14.055  1   59.44  ? 289 VAL A O   1 
ATOM   4436 C  CB  . VAL B 2 293 ? -18.891 -41.796 11.988  1   51.35  ? 289 VAL A CB  1 
ATOM   4437 C  CG1 . VAL B 2 293 ? -20.205 -41.138 11.59   1   51.39  ? 289 VAL A CG1 1 
ATOM   4438 C  CG2 . VAL B 2 293 ? -17.966 -40.8   12.695  1   48.84  ? 289 VAL A CG2 1 
ATOM   4439 N  N   . THR B 2 294 ? -19.299 -42.346 15.114  1   64.26  ? 290 THR A N   1 
ATOM   4440 C  CA  . THR B 2 294 ? -19.845 -42.06  16.444  1   69.79  ? 290 THR A CA  1 
ATOM   4441 C  C   . THR B 2 294 ? -19.186 -40.785 17      1   67.92  ? 290 THR A C   1 
ATOM   4442 O  O   . THR B 2 294 ? -18.424 -40.133 16.29   1   69.81  ? 290 THR A O   1 
ATOM   4443 C  CB  . THR B 2 294 ? -19.726 -43.287 17.365  1   70.91  ? 290 THR A CB  1 
ATOM   4444 O  OG1 . THR B 2 294 ? -18.389 -43.784 17.42   1   69.14  ? 290 THR A OG1 1 
ATOM   4445 C  CG2 . THR B 2 294 ? -20.605 -44.449 16.929  1   68.4   ? 290 THR A CG2 1 
ATOM   4446 N  N   . LYS B 2 295 ? -19.517 -40.382 18.239  1   65.51  ? 291 LYS A N   1 
ATOM   4447 C  CA  . LYS B 2 295 ? -18.84  -39.264 18.884  1   65.26  ? 291 LYS A CA  1 
ATOM   4448 C  C   . LYS B 2 295 ? -18.272 -39.664 20.255  1   71.97  ? 291 LYS A C   1 
ATOM   4449 O  O   . LYS B 2 295 ? -18.711 -39.112 21.28   1   70.21  ? 291 LYS A O   1 
ATOM   4450 C  CB  . LYS B 2 295 ? -19.771 -38.044 18.962  1   73.85  ? 291 LYS A CB  1 
ATOM   4451 C  CG  . LYS B 2 295 ? -19.269 -36.743 19.638  1   74.52  ? 291 LYS A CG  1 
ATOM   4452 C  CD  . LYS B 2 295 ? -19.627 -35.506 18.805  1   86.3   ? 291 LYS A CD  1 
ATOM   4453 C  CE  . LYS B 2 295 ? -19.447 -34.137 19.436  1   92.11  ? 291 LYS A CE  1 
ATOM   4454 N  NZ  . LYS B 2 295 ? -19.827 -33.006 18.567  1   75.55  ? 291 LYS A NZ  1 
ATOM   4455 N  N   . PRO B 2 296 ? -17.237 -40.555 20.334  1   69.26  ? 292 PRO A N   1 
ATOM   4456 C  CA  . PRO B 2 296 ? -16.656 -40.928 21.628  1   68.28  ? 292 PRO A CA  1 
ATOM   4457 C  C   . PRO B 2 296 ? -15.721 -39.83  22.152  1   62.92  ? 292 PRO A C   1 
ATOM   4458 O  O   . PRO B 2 296 ? -15.319 -38.949 21.389  1   64.4   ? 292 PRO A O   1 
ATOM   4459 C  CB  . PRO B 2 296 ? -15.953 -42.27  21.292  1   66.05  ? 292 PRO A CB  1 
ATOM   4460 C  CG  . PRO B 2 296 ? -15.487 -42.1   19.861  1   60.53  ? 292 PRO A CG  1 
ATOM   4461 C  CD  . PRO B 2 296 ? -16.53  -41.212 19.212  1   63.2   ? 292 PRO A CD  1 
ATOM   4462 N  N   . VAL B 2 297 ? -15.414 -39.898 23.457  1   63.22  ? 293 VAL A N   1 
ATOM   4463 C  CA  . VAL B 2 297 ? -14.64  -38.921 24.22   1   63.11  ? 293 VAL A CA  1 
ATOM   4464 C  C   . VAL B 2 297 ? -13.154 -39.225 24.066  1   63.27  ? 293 VAL A C   1 
ATOM   4465 O  O   . VAL B 2 297 ? -12.82  -40.375 23.79   1   61.92  ? 293 VAL A O   1 
ATOM   4466 C  CB  . VAL B 2 297 ? -15.023 -38.99  25.71   1   60.48  ? 293 VAL A CB  1 
ATOM   4467 C  CG1 . VAL B 2 297 ? -16.509 -38.715 25.946  1   63     ? 293 VAL A CG1 1 
ATOM   4468 C  CG2 . VAL B 2 297 ? -14.632 -40.32  26.32   1   59.78  ? 293 VAL A CG2 1 
ATOM   4469 N  N   . PRO B 2 298 ? -12.215 -38.263 24.286  1   65.6   ? 294 PRO A N   1 
ATOM   4470 C  CA  . PRO B 2 298 ? -10.792 -38.582 24.166  1   65.34  ? 294 PRO A CA  1 
ATOM   4471 C  C   . PRO B 2 298 ? -10.562 -39.72  25.174  1   71.18  ? 294 PRO A C   1 
ATOM   4472 O  O   . PRO B 2 298 ? -11.136 -39.701 26.275  1   71.71  ? 294 PRO A O   1 
ATOM   4473 C  CB  . PRO B 2 298 ? -10.087 -37.254 24.546  1   61.65  ? 294 PRO A CB  1 
ATOM   4474 C  CG  . PRO B 2 298 ? -11.07  -36.531 25.417  1   61.43  ? 294 PRO A CG  1 
ATOM   4475 C  CD  . PRO B 2 298 ? -12.423 -36.881 24.768  1   63.33  ? 294 PRO A CD  1 
ATOM   4476 N  N   . HIS B 2 299 ? -9.754  -40.719 24.765  1   63.79  ? 295 HIS A N   1 
ATOM   4477 C  CA  . HIS B 2 299 ? -9.445  -41.911 25.545  1   62.72  ? 295 HIS A CA  1 
ATOM   4478 C  C   . HIS B 2 299 ? -8.423  -41.595 26.64   1   63.79  ? 295 HIS A C   1 
ATOM   4479 O  O   . HIS B 2 299 ? -8.109  -42.46  27.455  1   63.27  ? 295 HIS A O   1 
ATOM   4480 C  CB  . HIS B 2 299 ? -8.972  -43.055 24.631  1   64.12  ? 295 HIS A CB  1 
ATOM   4481 C  CG  . HIS B 2 299 ? -7.596  -42.892 24.049  1   65.01  ? 295 HIS A CG  1 
ATOM   4482 N  ND1 . HIS B 2 299 ? -7.258  -41.851 23.207  1   62.73  ? 295 HIS A ND1 1 
ATOM   4483 C  CD2 . HIS B 2 299 ? -6.474  -43.607 24.231  1   67.52  ? 295 HIS A CD2 1 
ATOM   4484 C  CE1 . HIS B 2 299 ? -5.982  -41.948 22.882  1   64.88  ? 295 HIS A CE1 1 
ATOM   4485 N  NE2 . HIS B 2 299 ? -5.491  -43.016 23.486  1   70.52  ? 295 HIS A NE2 1 
ATOM   4486 N  N   . LEU B 2 300 ? -7.933  -40.361 26.612  1   64.39  ? 296 LEU A N   1 
ATOM   4487 C  CA  . LEU B 2 300 ? -6.921  -39.908 27.574  1   68.19  ? 296 LEU A CA  1 
ATOM   4488 C  C   . LEU B 2 300 ? -7.498  -38.712 28.289  1   69.17  ? 296 LEU A C   1 
ATOM   4489 O  O   . LEU B 2 300 ? -8.357  -38.062 27.713  1   75.13  ? 296 LEU A O   1 
ATOM   4490 C  CB  . LEU B 2 300 ? -5.666  -39.527 26.804  1   71.77  ? 296 LEU A CB  1 
ATOM   4491 C  CG  . LEU B 2 300 ? -5.002  -40.628 25.975  1   73.05  ? 296 LEU A CG  1 
ATOM   4492 C  CD1 . LEU B 2 300 ? -3.884  -40.047 25.138  1   68.42  ? 296 LEU A CD1 1 
ATOM   4493 C  CD2 . LEU B 2 300 ? -4.492  -41.759 26.841  1   76.26  ? 296 LEU A CD2 1 
ATOM   4494 N  N   . ARG B 2 301 ? -6.968  -38.391 29.465  1   81.94  ? 297 ARG A N   1 
ATOM   4495 C  CA  . ARG B 2 301 ? -7.413  -37.184 30.206  1   90.99  ? 297 ARG A CA  1 
ATOM   4496 C  C   . ARG B 2 301 ? -6.923  -35.929 29.466  1   93.42  ? 297 ARG A C   1 
ATOM   4497 O  O   . ARG B 2 301 ? -7.067  -34.829 30.04   1   83.9   ? 297 ARG A O   1 
ATOM   4498 C  CB  . ARG B 2 301 ? -6.866  -37.229 31.635  1   98.25  ? 297 ARG A CB  1 
ATOM   4499 C  CG  . ARG B 2 301 ? -7.711  -38.033 32.612  1   102.26 ? 297 ARG A CG  1 
ATOM   4500 C  CD  . ARG B 2 301 ? -6.927  -38.351 33.871  1   100.93 ? 297 ARG A CD  1 
ATOM   4501 N  NE  . ARG B 2 301 ? -5.711  -39.121 33.587  1   96.45  ? 297 ARG A NE  1 
ATOM   4502 C  CZ  . ARG B 2 301 ? -4.968  -39.719 34.51   1   94.6   ? 297 ARG A CZ  1 
ATOM   4503 N  NH1 . ARG B 2 301 ? -3.661  -39.81  34.347  1   100.29 ? 297 ARG A NH1 1 
ATOM   4504 N  NH2 . ARG B 2 301 ? -5.535  -40.223 35.591  1   97.79  ? 297 ARG A NH2 1 
ATOM   4505 N  N   . GLY C 1 1   ? -15.089 -24.17  -12.15  1   44.39  ? 171 GLY B N   1 
ATOM   4506 C  CA  . GLY C 1 1   ? -14.36  -24.933 -11.122 1   46.08  ? 171 GLY B CA  1 
ATOM   4507 C  C   . GLY C 1 1   ? -14.496 -24.327 -9.711  1   47.44  ? 171 GLY B C   1 
ATOM   4508 O  O   . GLY C 1 1   ? -15.286 -23.398 -9.461  1   45.26  ? 171 GLY B O   1 
ATOM   4509 N  N   . VAL C 1 2   ? -13.678 -24.864 -8.798  1   45.36  ? 172 VAL B N   1 
ATOM   4510 C  CA  . VAL C 1 2   ? -13.681 -24.502 -7.399  1   47.04  ? 172 VAL B CA  1 
ATOM   4511 C  C   . VAL C 1 2   ? -13.594 -22.975 -7.204  1   51.26  ? 172 VAL B C   1 
ATOM   4512 O  O   . VAL C 1 2   ? -14.063 -22.47  -6.183  1   53.9   ? 172 VAL B O   1 
ATOM   4513 C  CB  . VAL C 1 2   ? -12.577 -25.295 -6.656  1   45.94  ? 172 VAL B CB  1 
ATOM   4514 C  CG1 . VAL C 1 2   ? -11.209 -24.628 -6.805  1   42.89  ? 172 VAL B CG1 1 
ATOM   4515 C  CG2 . VAL C 1 2   ? -12.931 -25.552 -5.185  1   40.18  ? 172 VAL B CG2 1 
ATOM   4516 N  N   . ASN C 1 3   ? -13.03  -22.204 -8.147  1   51.78  ? 173 ASN B N   1 
ATOM   4517 C  CA  . ASN C 1 3   ? -12.95  -20.756 -7.94   1   48.6   ? 173 ASN B CA  1 
ATOM   4518 C  C   . ASN C 1 3   ? -14.33  -20.109 -7.87   1   46.21  ? 173 ASN B C   1 
ATOM   4519 O  O   . ASN C 1 3   ? -14.451 -19.004 -7.34   1   45.55  ? 173 ASN B O   1 
ATOM   4520 C  CB  . ASN C 1 3   ? -12.082 -20.063 -8.982  1   51.09  ? 173 ASN B CB  1 
ATOM   4521 C  CG  . ASN C 1 3   ? -10.635 -20.491 -8.887  1   52.46  ? 173 ASN B CG  1 
ATOM   4522 O  OD1 . ASN C 1 3   ? -10.234 -21.072 -7.875  1   54.21  ? 173 ASN B OD1 1 
ATOM   4523 N  ND2 . ASN C 1 3   ? -9.838  -20.236 -9.919  1   49.85  ? 173 ASN B ND2 1 
ATOM   4524 N  N   . GLU C 1 4   ? -15.345 -20.775 -8.448  1   50.18  ? 174 GLU B N   1 
ATOM   4525 C  CA  . GLU C 1 4   ? -16.744 -20.345 -8.404  1   53.02  ? 174 GLU B CA  1 
ATOM   4526 C  C   . GLU C 1 4   ? -17.562 -21.233 -7.446  1   50.18  ? 174 GLU B C   1 
ATOM   4527 O  O   . GLU C 1 4   ? -18.778 -21.257 -7.528  1   48.4   ? 174 GLU B O   1 
ATOM   4528 C  CB  . GLU C 1 4   ? -17.427 -20.376 -9.775  1   52.89  ? 174 GLU B CB  1 
ATOM   4529 C  CG  . GLU C 1 4   ? -16.481 -20.266 -10.967 1   61.63  ? 174 GLU B CG  1 
ATOM   4530 C  CD  . GLU C 1 4   ? -17.127 -20.354 -12.354 1   77.36  ? 174 GLU B CD  1 
ATOM   4531 O  OE1 . GLU C 1 4   ? -17.729 -21.398 -12.676 1   85.16  ? 174 GLU B OE1 1 
ATOM   4532 O  OE2 . GLU C 1 4   ? -17.039 -19.385 -13.142 1   83.98  ? 174 GLU B OE2 1 
ATOM   4533 N  N   . VAL C 1 5   ? -16.881 -21.998 -6.577  1   47.07  ? 175 VAL B N   1 
ATOM   4534 C  CA  . VAL C 1 5   ? -17.432 -22.739 -5.448  1   46.98  ? 175 VAL B CA  1 
ATOM   4535 C  C   . VAL C 1 5   ? -18.758 -23.399 -5.809  1   47.28  ? 175 VAL B C   1 
ATOM   4536 O  O   . VAL C 1 5   ? -19.775 -23.084 -5.203  1   46.96  ? 175 VAL B O   1 
ATOM   4537 C  CB  . VAL C 1 5   ? -17.514 -21.929 -4.131  1   44.22  ? 175 VAL B CB  1 
ATOM   4538 C  CG1 . VAL C 1 5   ? -16.129 -21.748 -3.533  1   44.23  ? 175 VAL B CG1 1 
ATOM   4539 C  CG2 . VAL C 1 5   ? -18.181 -20.572 -4.298  1   38.4   ? 175 VAL B CG2 1 
ATOM   4540 N  N   . PRO C 1 6   ? -18.786 -24.317 -6.797  1   50     ? 176 PRO B N   1 
ATOM   4541 C  CA  . PRO C 1 6   ? -20.014 -25.015 -7.178  1   50.75  ? 176 PRO B CA  1 
ATOM   4542 C  C   . PRO C 1 6   ? -20.829 -25.627 -6.038  1   53.27  ? 176 PRO B C   1 
ATOM   4543 O  O   . PRO C 1 6   ? -22.064 -25.651 -6.142  1   56.99  ? 176 PRO B O   1 
ATOM   4544 C  CB  . PRO C 1 6   ? -19.575 -26.09  -8.218  1   47.39  ? 176 PRO B CB  1 
ATOM   4545 C  CG  . PRO C 1 6   ? -18.075 -26.092 -8.168  1   45.4   ? 176 PRO B CG  1 
ATOM   4546 C  CD  . PRO C 1 6   ? -17.648 -24.72  -7.643  1   49.44  ? 176 PRO B CD  1 
ATOM   4547 N  N   . ASP C 1 7   ? -20.145 -26.114 -4.975  1   46.03  ? 177 ASP B N   1 
ATOM   4548 C  CA  . ASP C 1 7   ? -20.809 -26.819 -3.887  1   43.97  ? 177 ASP B CA  1 
ATOM   4549 C  C   . ASP C 1 7   ? -21.412 -25.878 -2.834  1   43.15  ? 177 ASP B C   1 
ATOM   4550 O  O   . ASP C 1 7   ? -22.129 -26.336 -1.944  1   42.43  ? 177 ASP B O   1 
ATOM   4551 C  CB  . ASP C 1 7   ? -19.922 -27.889 -3.27   1   44.55  ? 177 ASP B CB  1 
ATOM   4552 C  CG  . ASP C 1 7   ? -19.922 -29.184 -4.053  1   48.83  ? 177 ASP B CG  1 
ATOM   4553 O  OD1 . ASP C 1 7   ? -20.397 -29.116 -5.209  1   51.29  ? 177 ASP B OD1 1 
ATOM   4554 O  OD2 . ASP C 1 7   ? -19.506 -30.249 -3.505  1   47.13  ? 177 ASP B OD2 1 
ATOM   4555 N  N   . TYR C 1 8   ? -21.116 -24.572 -2.919  1   39.97  ? 178 TYR B N   1 
ATOM   4556 C  CA  . TYR C 1 8   ? -21.42  -23.639 -1.846  1   38.75  ? 178 TYR B CA  1 
ATOM   4557 C  C   . TYR C 1 8   ? -22.084 -22.365 -2.374  1   40.26  ? 178 TYR B C   1 
ATOM   4558 O  O   . TYR C 1 8   ? -22.563 -21.557 -1.582  1   42.16  ? 178 TYR B O   1 
ATOM   4559 C  CB  . TYR C 1 8   ? -20.154 -23.269 -1.054  1   35.49  ? 178 TYR B CB  1 
ATOM   4560 C  CG  . TYR C 1 8   ? -19.504 -24.47  -0.395  1   35.03  ? 178 TYR B CG  1 
ATOM   4561 C  CD1 . TYR C 1 8   ? -20.034 -25.027 0.762   1   35.06  ? 178 TYR B CD1 1 
ATOM   4562 C  CD2 . TYR C 1 8   ? -18.386 -25.079 -0.951  1   36.04  ? 178 TYR B CD2 1 
ATOM   4563 C  CE1 . TYR C 1 8   ? -19.456 -26.134 1.352   1   35.95  ? 178 TYR B CE1 1 
ATOM   4564 C  CE2 . TYR C 1 8   ? -17.791 -26.19  -0.367  1   35.96  ? 178 TYR B CE2 1 
ATOM   4565 C  CZ  . TYR C 1 8   ? -18.32  -26.714 0.799   1   37.05  ? 178 TYR B CZ  1 
ATOM   4566 O  OH  . TYR C 1 8   ? -17.759 -27.833 1.371   1   38.09  ? 178 TYR B OH  1 
ATOM   4567 N  N   . HIS C 1 9   ? -22.165 -22.173 -3.692  1   41.28  ? 179 HIS B N   1 
ATOM   4568 C  CA  . HIS C 1 9   ? -22.552 -20.842 -4.147  1   48.95  ? 179 HIS B CA  1 
ATOM   4569 C  C   . HIS C 1 9   ? -24.03  -20.551 -3.851  1   48.97  ? 179 HIS B C   1 
ATOM   4570 O  O   . HIS C 1 9   ? -24.397 -19.392 -3.667  1   49.72  ? 179 HIS B O   1 
ATOM   4571 C  CB  . HIS C 1 9   ? -22.079 -20.556 -5.583  1   56.45  ? 179 HIS B CB  1 
ATOM   4572 C  CG  . HIS C 1 9   ? -23     -21.111 -6.605  1   66.53  ? 179 HIS B CG  1 
ATOM   4573 N  ND1 . HIS C 1 9   ? -23.68  -20.297 -7.484  1   71.01  ? 179 HIS B ND1 1 
ATOM   4574 C  CD2 . HIS C 1 9   ? -23.376 -22.391 -6.86   1   67.06  ? 179 HIS B CD2 1 
ATOM   4575 C  CE1 . HIS C 1 9   ? -24.448 -21.081 -8.245  1   79.16  ? 179 HIS B CE1 1 
ATOM   4576 N  NE2 . HIS C 1 9   ? -24.276 -22.351 -7.884  1   71.65  ? 179 HIS B NE2 1 
ATOM   4577 N  N   . GLU C 1 10  ? -24.884 -21.588 -3.85   1   47.86  ? 180 GLU B N   1 
ATOM   4578 C  CA  . GLU C 1 10  ? -26.281 -21.431 -3.476  1   46.64  ? 180 GLU B CA  1 
ATOM   4579 C  C   . GLU C 1 10  ? -26.386 -21.11  -1.991  1   45.33  ? 180 GLU B C   1 
ATOM   4580 O  O   . GLU C 1 10  ? -27.074 -20.151 -1.612  1   44.23  ? 180 GLU B O   1 
ATOM   4581 C  CB  . GLU C 1 10  ? -27.098 -22.701 -3.637  1   53.06  ? 180 GLU B CB  1 
ATOM   4582 C  CG  . GLU C 1 10  ? -27.887 -22.78  -4.938  1   65.79  ? 180 GLU B CG  1 
ATOM   4583 C  CD  . GLU C 1 10  ? -28.869 -23.951 -4.808  1   79.87  ? 180 GLU B CD  1 
ATOM   4584 O  OE1 . GLU C 1 10  ? -29.887 -23.815 -4.079  1   66.02  ? 180 GLU B OE1 1 
ATOM   4585 O  OE2 . GLU C 1 10  ? -28.602 -25.028 -5.41   1   88     ? 180 GLU B OE2 1 
ATOM   4586 N  N   . ASP C 1 11  ? -25.676 -21.902 -1.168  1   41.59  ? 181 ASP B N   1 
ATOM   4587 C  CA  . ASP C 1 11  ? -25.666 -21.68  0.266   1   40.71  ? 181 ASP B CA  1 
ATOM   4588 C  C   . ASP C 1 11  ? -25.231 -20.241 0.509   1   42.21  ? 181 ASP B C   1 
ATOM   4589 O  O   . ASP C 1 11  ? -25.846 -19.552 1.316   1   43.91  ? 181 ASP B O   1 
ATOM   4590 C  CB  . ASP C 1 11  ? -24.774 -22.656 1.019   1   42.15  ? 181 ASP B CB  1 
ATOM   4591 C  CG  . ASP C 1 11  ? -25.269 -24.086 1.186   1   48.32  ? 181 ASP B CG  1 
ATOM   4592 O  OD1 . ASP C 1 11  ? -26.46  -24.352 0.885   1   54.26  ? 181 ASP B OD1 1 
ATOM   4593 O  OD2 . ASP C 1 11  ? -24.452 -24.944 1.596   1   51.29  ? 181 ASP B OD2 1 
ATOM   4594 N  N   . ILE C 1 12  ? -24.18  -19.802 -0.207  1   39.41  ? 182 ILE B N   1 
ATOM   4595 C  CA  . ILE C 1 12  ? -23.632 -18.478 -0.003  1   39.81  ? 182 ILE B CA  1 
ATOM   4596 C  C   . ILE C 1 12  ? -24.639 -17.408 -0.437  1   41.31  ? 182 ILE B C   1 
ATOM   4597 O  O   . ILE C 1 12  ? -24.805 -16.4   0.25    1   43.79  ? 182 ILE B O   1 
ATOM   4598 C  CB  . ILE C 1 12  ? -22.277 -18.307 -0.709  1   37.47  ? 182 ILE B CB  1 
ATOM   4599 C  CG1 . ILE C 1 12  ? -21.193 -19.101 0.008   1   38.77  ? 182 ILE B CG1 1 
ATOM   4600 C  CG2 . ILE C 1 12  ? -21.914 -16.827 -0.817  1   32.88  ? 182 ILE B CG2 1 
ATOM   4601 C  CD1 . ILE C 1 12  ? -20.016 -19.495 -0.872  1   35.44  ? 182 ILE B CD1 1 
ATOM   4602 N  N   . HIS C 1 13  ? -25.279 -17.593 -1.593  1   39.82  ? 183 HIS B N   1 
ATOM   4603 C  CA  . HIS C 1 13  ? -26.253 -16.617 -2.036  1   37.97  ? 183 HIS B CA  1 
ATOM   4604 C  C   . HIS C 1 13  ? -27.344 -16.484 -0.972  1   42.52  ? 183 HIS B C   1 
ATOM   4605 O  O   . HIS C 1 13  ? -27.668 -15.374 -0.541  1   42.65  ? 183 HIS B O   1 
ATOM   4606 C  CB  . HIS C 1 13  ? -26.842 -17.066 -3.365  1   38.85  ? 183 HIS B CB  1 
ATOM   4607 C  CG  . HIS C 1 13  ? -27.922 -16.161 -3.837  1   40.39  ? 183 HIS B CG  1 
ATOM   4608 N  ND1 . HIS C 1 13  ? -27.6   -14.918 -4.341  1   46.61  ? 183 HIS B ND1 1 
ATOM   4609 C  CD2 . HIS C 1 13  ? -29.242 -16.242 -3.855  1   36.11  ? 183 HIS B CD2 1 
ATOM   4610 C  CE1 . HIS C 1 13  ? -28.706 -14.265 -4.655  1   39.15  ? 183 HIS B CE1 1 
ATOM   4611 N  NE2 . HIS C 1 13  ? -29.699 -15.069 -4.381  1   38.1   ? 183 HIS B NE2 1 
ATOM   4612 N  N   . THR C 1 14  ? -27.896 -17.629 -0.533  1   41.5   ? 184 THR B N   1 
ATOM   4613 C  CA  . THR C 1 14  ? -28.948 -17.612 0.465   1   39.57  ? 184 THR B CA  1 
ATOM   4614 C  C   . THR C 1 14  ? -28.483 -16.841 1.694   1   42.65  ? 184 THR B C   1 
ATOM   4615 O  O   . THR C 1 14  ? -29.24  -16.029 2.198   1   46.29  ? 184 THR B O   1 
ATOM   4616 C  CB  . THR C 1 14  ? -29.352 -19.016 0.882   1   37.28  ? 184 THR B CB  1 
ATOM   4617 O  OG1 . THR C 1 14  ? -30.12  -19.562 -0.181  1   38.82  ? 184 THR B OG1 1 
ATOM   4618 C  CG2 . THR C 1 14  ? -30.27  -18.966 2.082   1   36.84  ? 184 THR B CG2 1 
ATOM   4619 N  N   . TYR C 1 15  ? -27.25  -17.103 2.157   1   41.69  ? 185 TYR B N   1 
ATOM   4620 C  CA  . TYR C 1 15  ? -26.698 -16.494 3.354   1   38.97  ? 185 TYR B CA  1 
ATOM   4621 C  C   . TYR C 1 15  ? -26.639 -14.973 3.196   1   39.26  ? 185 TYR B C   1 
ATOM   4622 O  O   . TYR C 1 15  ? -27.07  -14.24  4.085   1   40.96  ? 185 TYR B O   1 
ATOM   4623 C  CB  . TYR C 1 15  ? -25.327 -17.086 3.682   1   38.57  ? 185 TYR B CB  1 
ATOM   4624 C  CG  . TYR C 1 15  ? -24.768 -16.51  4.972   1   42.39  ? 185 TYR B CG  1 
ATOM   4625 C  CD1 . TYR C 1 15  ? -25.497 -16.58  6.155   1   45.71  ? 185 TYR B CD1 1 
ATOM   4626 C  CD2 . TYR C 1 15  ? -23.544 -15.853 5.004   1   42.6   ? 185 TYR B CD2 1 
ATOM   4627 C  CE1 . TYR C 1 15  ? -25.045 -16.003 7.331   1   46.26  ? 185 TYR B CE1 1 
ATOM   4628 C  CE2 . TYR C 1 15  ? -23.054 -15.31  6.184   1   46.49  ? 185 TYR B CE2 1 
ATOM   4629 C  CZ  . TYR C 1 15  ? -23.819 -15.368 7.342   1   51.62  ? 185 TYR B CZ  1 
ATOM   4630 O  OH  . TYR C 1 15  ? -23.433 -14.831 8.535   1   57.1   ? 185 TYR B OH  1 
ATOM   4631 N  N   . LEU C 1 16  ? -26.099 -14.494 2.072   1   37.2   ? 186 LEU B N   1 
ATOM   4632 C  CA  . LEU C 1 16  ? -25.956 -13.072 1.837   1   36.53  ? 186 LEU B CA  1 
ATOM   4633 C  C   . LEU C 1 16  ? -27.334 -12.409 1.771   1   42.92  ? 186 LEU B C   1 
ATOM   4634 O  O   . LEU C 1 16  ? -27.504 -11.273 2.233   1   46.7   ? 186 LEU B O   1 
ATOM   4635 C  CB  . LEU C 1 16  ? -25.173 -12.863 0.55    1   37.57  ? 186 LEU B CB  1 
ATOM   4636 C  CG  . LEU C 1 16  ? -23.72  -13.344 0.54    1   38.99  ? 186 LEU B CG  1 
ATOM   4637 C  CD1 . LEU C 1 16  ? -23.151 -13.232 -0.883  1   37.69  ? 186 LEU B CD1 1 
ATOM   4638 C  CD2 . LEU C 1 16  ? -22.888 -12.554 1.522   1   36.08  ? 186 LEU B CD2 1 
ATOM   4639 N  N   . ARG C 1 17  ? -28.313 -13.112 1.216   1   42.31  ? 187 ARG B N   1 
ATOM   4640 C  CA  . ARG C 1 17  ? -29.658 -12.512 1.042   1   44.34  ? 187 ARG B CA  1 
ATOM   4641 C  C   . ARG C 1 17  ? -30.261 -12.194 2.418   1   45.47  ? 187 ARG B C   1 
ATOM   4642 O  O   . ARG C 1 17  ? -31.029 -11.23  2.522   1   47.34  ? 187 ARG B O   1 
ATOM   4643 C  CB  . ARG C 1 17  ? -30.507 -13.45  0.183   1   40.98  ? 187 ARG B CB  1 
ATOM   4644 C  CG  . ARG C 1 17  ? -30.218 -13.338 -1.305  1   40.29  ? 187 ARG B CG  1 
ATOM   4645 C  CD  . ARG C 1 17  ? -30.794 -12.063 -1.881  1   38.52  ? 187 ARG B CD  1 
ATOM   4646 N  NE  . ARG C 1 17  ? -32.243 -11.973 -1.68   1   36.13  ? 187 ARG B NE  1 
ATOM   4647 C  CZ  . ARG C 1 17  ? -33.147 -12.542 -2.457  1   36.15  ? 187 ARG B CZ  1 
ATOM   4648 N  NH1 . ARG C 1 17  ? -32.816 -12.95  -3.665  1   40.03  ? 187 ARG B NH1 1 
ATOM   4649 N  NH2 . ARG C 1 17  ? -34.383 -12.693 -2.029  1   33.7   ? 187 ARG B NH2 1 
ATOM   4650 N  N   . GLU C 1 18  ? -29.905 -12.968 3.432   1   44.76  ? 188 GLU B N   1 
ATOM   4651 C  CA  . GLU C 1 18  ? -30.426 -12.738 4.797   1   47.61  ? 188 GLU B CA  1 
ATOM   4652 C  C   . GLU C 1 18  ? -29.564 -11.678 5.479   1   48.49  ? 188 GLU B C   1 
ATOM   4653 O  O   . GLU C 1 18  ? -30.109 -10.836 6.208   1   51.91  ? 188 GLU B O   1 
ATOM   4654 C  CB  . GLU C 1 18  ? -30.423 -14.085 5.516   1   45.86  ? 188 GLU B CB  1 
ATOM   4655 C  CG  . GLU C 1 18  ? -30.12  -14.005 7.008   1   59.87  ? 188 GLU B CG  1 
ATOM   4656 C  CD  . GLU C 1 18  ? -29.675 -15.341 7.569   1   71.13  ? 188 GLU B CD  1 
ATOM   4657 O  OE1 . GLU C 1 18  ? -29.379 -16.245 6.762   1   74.25  ? 188 GLU B OE1 1 
ATOM   4658 O  OE2 . GLU C 1 18  ? -29.629 -15.479 8.807   1   68.63  ? 188 GLU B OE2 1 
ATOM   4659 N  N   . MET C 1 19  ? -28.267 -11.718 5.223   1   42.77  ? 189 MET B N   1 
ATOM   4660 C  CA  . MET C 1 19  ? -27.341 -10.778 5.885   1   44.05  ? 189 MET B CA  1 
ATOM   4661 C  C   . MET C 1 19  ? -27.594 -9.367  5.348   1   44.92  ? 189 MET B C   1 
ATOM   4662 O  O   . MET C 1 19  ? -27.351 -8.409  6.088   1   45.54  ? 189 MET B O   1 
ATOM   4663 C  CB  . MET C 1 19  ? -25.9   -11.228 5.646   1   41.12  ? 189 MET B CB  1 
ATOM   4664 C  CG  . MET C 1 19  ? -25.467 -12.389 6.502   1   50.04  ? 189 MET B CG  1 
ATOM   4665 S  SD  . MET C 1 19  ? -26.445 -12.543 8.007   1   58.11  ? 189 MET B SD  1 
ATOM   4666 C  CE  . MET C 1 19  ? -25.29  -11.88  9.211   1   63.77  ? 189 MET B CE  1 
ATOM   4667 N  N   . GLU C 1 20  ? -28.08  -9.254  4.113   1   44.39  ? 190 GLU B N   1 
ATOM   4668 C  CA  . GLU C 1 20  ? -28.265 -7.924  3.554   1   43.72  ? 190 GLU B CA  1 
ATOM   4669 C  C   . GLU C 1 20  ? -29.407 -7.218  4.284   1   44.77  ? 190 GLU B C   1 
ATOM   4670 O  O   . GLU C 1 20  ? -29.322 -6.014  4.522   1   46.37  ? 190 GLU B O   1 
ATOM   4671 C  CB  . GLU C 1 20  ? -28.374 -7.936  2.027   1   40.39  ? 190 GLU B CB  1 
ATOM   4672 C  CG  . GLU C 1 20  ? -29.671 -8.517  1.464   1   40.52  ? 190 GLU B CG  1 
ATOM   4673 C  CD  . GLU C 1 20  ? -29.722 -8.215  -0.025  1   44.66  ? 190 GLU B CD  1 
ATOM   4674 O  OE1 . GLU C 1 20  ? -28.765 -7.554  -0.533  1   41.81  ? 190 GLU B OE1 1 
ATOM   4675 O  OE2 . GLU C 1 20  ? -30.691 -8.647  -0.69   1   43.3   ? 190 GLU B OE2 1 
ATOM   4676 N  N   . VAL C 1 21  ? -30.453 -7.978  4.635   1   44.3   ? 191 VAL B N   1 
ATOM   4677 C  CA  . VAL C 1 21  ? -31.544 -7.502  5.469   1   47.52  ? 191 VAL B CA  1 
ATOM   4678 C  C   . VAL C 1 21  ? -31.023 -7.121  6.858   1   52.38  ? 191 VAL B C   1 
ATOM   4679 O  O   . VAL C 1 21  ? -31.435 -6.12   7.423   1   60.32  ? 191 VAL B O   1 
ATOM   4680 C  CB  . VAL C 1 21  ? -32.696 -8.53   5.565   1   44.73  ? 191 VAL B CB  1 
ATOM   4681 C  CG1 . VAL C 1 21  ? -33.831 -8.035  6.445   1   39.04  ? 191 VAL B CG1 1 
ATOM   4682 C  CG2 . VAL C 1 21  ? -33.266 -8.869  4.192   1   44.46  ? 191 VAL B CG2 1 
ATOM   4683 N  N   . LYS C 1 22  ? -30.155 -7.946  7.437   1   58.26  ? 192 LYS B N   1 
ATOM   4684 C  CA  . LYS C 1 22  ? -29.598 -7.653  8.75    1   62.84  ? 192 LYS B CA  1 
ATOM   4685 C  C   . LYS C 1 22  ? -28.721 -6.387  8.728   1   60.27  ? 192 LYS B C   1 
ATOM   4686 O  O   . LYS C 1 22  ? -28.707 -5.648  9.695   1   66.51  ? 192 LYS B O   1 
ATOM   4687 C  CB  . LYS C 1 22  ? -28.834 -8.875  9.281   1   70.34  ? 192 LYS B CB  1 
ATOM   4688 C  CG  . LYS C 1 22  ? -28.623 -8.922  10.803  1   88.7   ? 192 LYS B CG  1 
ATOM   4689 C  CD  . LYS C 1 22  ? -27.311 -9.504  11.337  1   95.13  ? 192 LYS B CD  1 
ATOM   4690 C  CE  . LYS C 1 22  ? -26.119 -8.633  11.031  1   93.57  ? 192 LYS B CE  1 
ATOM   4691 N  NZ  . LYS C 1 22  ? -26.282 -7.268  11.555  1   89.99  ? 192 LYS B NZ  1 
ATOM   4692 N  N   . CYS C 1 23  ? -27.953 -6.137  7.659   1   57.67  ? 193 CYS B N   1 
ATOM   4693 C  CA  . CYS C 1 23  ? -26.937 -5.085  7.63    1   52.79  ? 193 CYS B CA  1 
ATOM   4694 C  C   . CYS C 1 23  ? -27.488 -3.815  6.98    1   55.7   ? 193 CYS B C   1 
ATOM   4695 O  O   . CYS C 1 23  ? -26.703 -2.972  6.524   1   58.36  ? 193 CYS B O   1 
ATOM   4696 C  CB  . CYS C 1 23  ? -25.683 -5.515  6.86    1   47.12  ? 193 CYS B CB  1 
ATOM   4697 S  SG  . CYS C 1 23  ? -24.703 -6.799  7.705   1   64.31  ? 193 CYS B SG  1 
ATOM   4698 N  N   . LYS C 1 24  ? -28.825 -3.7    6.902   1   48.17  ? 194 LYS B N   1 
ATOM   4699 C  CA  . LYS C 1 24  ? -29.415 -2.653  6.089   1   48.35  ? 194 LYS B CA  1 
ATOM   4700 C  C   . LYS C 1 24  ? -29.515 -1.353  6.894   1   51.53  ? 194 LYS B C   1 
ATOM   4701 O  O   . LYS C 1 24  ? -29.949 -1.343  8.044   1   55.06  ? 194 LYS B O   1 
ATOM   4702 C  CB  . LYS C 1 24  ? -30.778 -3.067  5.534   1   50.67  ? 194 LYS B CB  1 
ATOM   4703 C  CG  . LYS C 1 24  ? -31.414 -1.958  4.711   1   55.42  ? 194 LYS B CG  1 
ATOM   4704 C  CD  . LYS C 1 24  ? -32.767 -2.3    4.097   1   59.61  ? 194 LYS B CD  1 
ATOM   4705 C  CE  . LYS C 1 24  ? -33.152 -1.361  2.987   1   62.02  ? 194 LYS B CE  1 
ATOM   4706 N  NZ  . LYS C 1 24  ? -34.572 -1.486  2.624   1   67.89  ? 194 LYS B NZ  1 
ATOM   4707 N  N   . PRO C 1 25  ? -29.142 -0.198  6.308   1   49     ? 195 PRO B N   1 
ATOM   4708 C  CA  . PRO C 1 25  ? -29.37  1.101   6.952   1   49.84  ? 195 PRO B CA  1 
ATOM   4709 C  C   . PRO C 1 25  ? -30.845 1.394   7.175   1   50.01  ? 195 PRO B C   1 
ATOM   4710 O  O   . PRO C 1 25  ? -31.683 0.804   6.52    1   55.29  ? 195 PRO B O   1 
ATOM   4711 C  CB  . PRO C 1 25  ? -28.802 2.122   5.946   1   51.58  ? 195 PRO B CB  1 
ATOM   4712 C  CG  . PRO C 1 25  ? -27.855 1.306   5.063   1   49.21  ? 195 PRO B CG  1 
ATOM   4713 C  CD  . PRO C 1 25  ? -28.459 -0.097  5.007   1   48.47  ? 195 PRO B CD  1 
ATOM   4714 N  N   . LYS C 1 26  ? -31.099 2.421   7.975   1   50.72  ? 196 LYS B N   1 
ATOM   4715 C  CA  . LYS C 1 26  ? -32.478 2.9     8.165   1   56.99  ? 196 LYS B CA  1 
ATOM   4716 C  C   . LYS C 1 26  ? -32.824 3.772   6.962   1   60.41  ? 196 LYS B C   1 
ATOM   4717 O  O   . LYS C 1 26  ? -32.183 4.818   6.794   1   54.41  ? 196 LYS B O   1 
ATOM   4718 C  CB  . LYS C 1 26  ? -32.505 3.81    9.388   1   65.86  ? 196 LYS B CB  1 
ATOM   4719 C  CG  . LYS C 1 26  ? -33.852 4.361   9.809   1   85.53  ? 196 LYS B CG  1 
ATOM   4720 C  CD  . LYS C 1 26  ? -33.737 5.21    11.069  1   92.98  ? 196 LYS B CD  1 
ATOM   4721 C  CE  . LYS C 1 26  ? -35.052 5.787   11.491  1   97.24  ? 196 LYS B CE  1 
ATOM   4722 N  NZ  . LYS C 1 26  ? -34.93  6.601   12.703  1   100.68 ? 196 LYS B NZ  1 
ATOM   4723 N  N   . VAL C 1 27  ? -33.779 3.34    6.147   1   61.43  ? 197 VAL B N   1 
ATOM   4724 C  CA  . VAL C 1 27  ? -34.228 4.185   5.012   1   59.95  ? 197 VAL B CA  1 
ATOM   4725 C  C   . VAL C 1 27  ? -34.866 5.438   5.612   1   64.53  ? 197 VAL B C   1 
ATOM   4726 O  O   . VAL C 1 27  ? -35.964 5.318   6.17    1   66.4   ? 197 VAL B O   1 
ATOM   4727 C  CB  . VAL C 1 27  ? -35.249 3.43    4.152   1   63.46  ? 197 VAL B CB  1 
ATOM   4728 C  CG1 . VAL C 1 27  ? -35.527 4.155   2.844   1   57.17  ? 197 VAL B CG1 1 
ATOM   4729 C  CG2 . VAL C 1 27  ? -34.834 1.986   3.912   1   64.63  ? 197 VAL B CG2 1 
ATOM   4730 N  N   . GLY C 1 28  ? -34.207 6.583   5.533   1   61.87  ? 198 GLY B N   1 
ATOM   4731 C  CA  . GLY C 1 28  ? -34.814 7.762   6.163   1   73.98  ? 198 GLY B CA  1 
ATOM   4732 C  C   . GLY C 1 28  ? -34.05  8.217   7.38    1   78.03  ? 198 GLY B C   1 
ATOM   4733 O  O   . GLY C 1 28  ? -34.679 8.772   8.299   1   76.98  ? 198 GLY B O   1 
ATOM   4734 N  N   . TYR C 1 29  ? -32.737 8.022   7.365   1   66.94  ? 199 TYR B N   1 
ATOM   4735 C  CA  . TYR C 1 29  ? -31.896 8.427   8.511   1   58.29  ? 199 TYR B CA  1 
ATOM   4736 C  C   . TYR C 1 29  ? -31.489 9.868   8.326   1   58.44  ? 199 TYR B C   1 
ATOM   4737 O  O   . TYR C 1 29  ? -31.199 10.532  9.331   1   61.2   ? 199 TYR B O   1 
ATOM   4738 C  CB  . TYR C 1 29  ? -30.732 7.432   8.613   1   54.06  ? 199 TYR B CB  1 
ATOM   4739 C  CG  . TYR C 1 29  ? -29.502 7.603   7.732   1   46.86  ? 199 TYR B CG  1 
ATOM   4740 C  CD1 . TYR C 1 29  ? -28.656 8.693   7.868   1   45.56  ? 199 TYR B CD1 1 
ATOM   4741 C  CD2 . TYR C 1 29  ? -29.156 6.633   6.802   1   43.63  ? 199 TYR B CD2 1 
ATOM   4742 C  CE1 . TYR C 1 29  ? -27.536 8.842   7.073   1   45.68  ? 199 TYR B CE1 1 
ATOM   4743 C  CE2 . TYR C 1 29  ? -28.029 6.761   6.011   1   43.98  ? 199 TYR B CE2 1 
ATOM   4744 C  CZ  . TYR C 1 29  ? -27.216 7.869   6.147   1   46.51  ? 199 TYR B CZ  1 
ATOM   4745 O  OH  . TYR C 1 29  ? -26.103 8.011   5.375   1   45.96  ? 199 TYR B OH  1 
ATOM   4746 N  N   . MET C 1 30  ? -31.469 10.35   7.086   1   53.69  ? 200 MET B N   1 
ATOM   4747 C  CA  . MET C 1 30  ? -30.937 11.717  6.855   1   57.09  ? 200 MET B CA  1 
ATOM   4748 C  C   . MET C 1 30  ? -31.88  12.771  7.451   1   62.5   ? 200 MET B C   1 
ATOM   4749 O  O   . MET C 1 30  ? -31.387 13.76   8.002   1   61.27  ? 200 MET B O   1 
ATOM   4750 C  CB  . MET C 1 30  ? -30.713 11.976  5.365   1   57.6   ? 200 MET B CB  1 
ATOM   4751 C  CG  . MET C 1 30  ? -29.672 13.026  5.089   1   61.88  ? 200 MET B CG  1 
ATOM   4752 S  SD  . MET C 1 30  ? -28.073 12.546  5.766   1   63.75  ? 200 MET B SD  1 
ATOM   4753 C  CE  . MET C 1 30  ? -27.549 11.389  4.496   1   61.03  ? 200 MET B CE  1 
ATOM   4754 N  N   . LYS C 1 31  ? -33.185 12.562  7.327   1   67.66  ? 201 LYS B N   1 
ATOM   4755 C  CA  . LYS C 1 31  ? -34.167 13.505  7.909   1   72.85  ? 201 LYS B CA  1 
ATOM   4756 C  C   . LYS C 1 31  ? -33.959 13.551  9.421   1   72.39  ? 201 LYS B C   1 
ATOM   4757 O  O   . LYS C 1 31  ? -34.271 14.588  10.027  1   74.5   ? 201 LYS B O   1 
ATOM   4758 C  CB  . LYS C 1 31  ? -35.58  13.045  7.553   1   81.96  ? 201 LYS B CB  1 
ATOM   4759 C  CG  . LYS C 1 31  ? -35.741 12.544  6.129   1   97.69  ? 201 LYS B CG  1 
ATOM   4760 C  CD  . LYS C 1 31  ? -37.122 11.96   5.86    1   108.78 ? 201 LYS B CD  1 
ATOM   4761 C  CE  . LYS C 1 31  ? -37.556 11.008  6.927   1   112.61 ? 201 LYS B CE  1 
ATOM   4762 N  NZ  . LYS C 1 31  ? -37.859 9.685   6.376   1   106.7  ? 201 LYS B NZ  1 
ATOM   4763 N  N   . LYS C 1 32  ? -33.447 12.465  9.995   1   71.1   ? 202 LYS B N   1 
ATOM   4764 C  CA  . LYS C 1 32  ? -33.179 12.43   11.426  1   71.98  ? 202 LYS B CA  1 
ATOM   4765 C  C   . LYS C 1 32  ? -31.814 13.034  11.766  1   66.82  ? 202 LYS B C   1 
ATOM   4766 O  O   . LYS C 1 32  ? -31.492 13.202  12.933  1   67.4   ? 202 LYS B O   1 
ATOM   4767 C  CB  . LYS C 1 32  ? -33.281 10.983  11.932  1   79.55  ? 202 LYS B CB  1 
ATOM   4768 C  CG  . LYS C 1 32  ? -34.577 10.626  12.671  1   95.12  ? 202 LYS B CG  1 
ATOM   4769 C  CD  . LYS C 1 32  ? -35.89  10.975  11.973  1   107.03 ? 202 LYS B CD  1 
ATOM   4770 C  CE  . LYS C 1 32  ? -37.138 10.512  12.665  1   114.78 ? 202 LYS B CE  1 
ATOM   4771 N  NZ  . LYS C 1 32  ? -37.234 9.051   12.602  1   112.59 ? 202 LYS B NZ  1 
ATOM   4772 N  N   . GLN C 1 33  ? -30.981 13.315  10.756  1   62.56  ? 203 GLN B N   1 
ATOM   4773 C  CA  . GLN C 1 33  ? -29.699 13.977  10.969  1   57.97  ? 203 GLN B CA  1 
ATOM   4774 C  C   . GLN C 1 33  ? -29.891 15.491  10.909  1   58.68  ? 203 GLN B C   1 
ATOM   4775 O  O   . GLN C 1 33  ? -30.265 16.047  9.873   1   60.14  ? 203 GLN B O   1 
ATOM   4776 C  CB  . GLN C 1 33  ? -28.724 13.541  9.88    1   55.92  ? 203 GLN B CB  1 
ATOM   4777 C  CG  . GLN C 1 33  ? -28.247 12.102  10.025  1   53.69  ? 203 GLN B CG  1 
ATOM   4778 C  CD  . GLN C 1 33  ? -27.208 11.921  11.114  1   52.9   ? 203 GLN B CD  1 
ATOM   4779 O  OE1 . GLN C 1 33  ? -26.63  12.889  11.625  1   52.3   ? 203 GLN B OE1 1 
ATOM   4780 N  NE2 . GLN C 1 33  ? -26.966 10.665  11.479  1   50.16  ? 203 GLN B NE2 1 
ATOM   4781 N  N   . PRO C 1 34  ? -29.717 16.221  12.03   1   60.84  ? 204 PRO B N   1 
ATOM   4782 C  CA  . PRO C 1 34  ? -29.996 17.659  12.045  1   63.34  ? 204 PRO B CA  1 
ATOM   4783 C  C   . PRO C 1 34  ? -29.11  18.494  11.125  1   63.68  ? 204 PRO B C   1 
ATOM   4784 O  O   . PRO C 1 34  ? -29.601 19.441  10.544  1   67.85  ? 204 PRO B O   1 
ATOM   4785 C  CB  . PRO C 1 34  ? -29.897 18.076  13.52   1   62.57  ? 204 PRO B CB  1 
ATOM   4786 C  CG  . PRO C 1 34  ? -29.056 16.992  14.136  1   61.56  ? 204 PRO B CG  1 
ATOM   4787 C  CD  . PRO C 1 34  ? -29.316 15.71   13.346  1   59.74  ? 204 PRO B CD  1 
ATOM   4788 N  N   . ASP C 1 35  ? -27.813 18.172  11.05   1   66.02  ? 205 ASP B N   1 
ATOM   4789 C  CA  . ASP C 1 35  ? -26.84  19.032  10.322  1   66.99  ? 205 ASP B CA  1 
ATOM   4790 C  C   . ASP C 1 35  ? -26.193 18.359  9.117   1   65.96  ? 205 ASP B C   1 
ATOM   4791 O  O   . ASP C 1 35  ? -25.274 18.971  8.555   1   71.85  ? 205 ASP B O   1 
ATOM   4792 C  CB  . ASP C 1 35  ? -25.68  19.416  11.222  1   68.86  ? 205 ASP B CB  1 
ATOM   4793 C  CG  . ASP C 1 35  ? -25.113 20.811  11.027  1   75.83  ? 205 ASP B CG  1 
ATOM   4794 O  OD1 . ASP C 1 35  ? -25.914 21.738  10.799  1   78.08  ? 205 ASP B OD1 1 
ATOM   4795 O  OD2 . ASP C 1 35  ? -23.877 20.953  11.111  1   79.64  ? 205 ASP B OD2 1 
ATOM   4796 N  N   . ILE C 1 36  ? -26.61  17.157  8.74    1   63.18  ? 206 ILE B N   1 
ATOM   4797 C  CA  . ILE C 1 36  ? -26.013 16.58   7.501   1   61.67  ? 206 ILE B CA  1 
ATOM   4798 C  C   . ILE C 1 36  ? -27.128 16.279  6.49    1   63.94  ? 206 ILE B C   1 
ATOM   4799 O  O   . ILE C 1 36  ? -28.263 16.012  6.919   1   65.16  ? 206 ILE B O   1 
ATOM   4800 C  CB  . ILE C 1 36  ? -25.084 15.38   7.778   1   57.59  ? 206 ILE B CB  1 
ATOM   4801 C  CG1 . ILE C 1 36  ? -25.819 14.164  8.293   1   55.21  ? 206 ILE B CG1 1 
ATOM   4802 C  CG2 . ILE C 1 36  ? -23.94  15.778  8.711   1   59.18  ? 206 ILE B CG2 1 
ATOM   4803 C  CD1 . ILE C 1 36  ? -24.926 12.949  8.456   1   56.86  ? 206 ILE B CD1 1 
ATOM   4804 N  N   . THR C 1 37  ? -26.801 16.357  5.198   1   63.2   ? 207 THR B N   1 
ATOM   4805 C  CA  . THR C 1 37  ? -27.803 16.175  4.135   1   61.09  ? 207 THR B CA  1 
ATOM   4806 C  C   . THR C 1 37  ? -27.373 15.085  3.188   1   57.25  ? 207 THR B C   1 
ATOM   4807 O  O   . THR C 1 37  ? -26.217 14.655  3.271   1   58.27  ? 207 THR B O   1 
ATOM   4808 C  CB  . THR C 1 37  ? -27.922 17.502  3.395   1   64.69  ? 207 THR B CB  1 
ATOM   4809 O  OG1 . THR C 1 37  ? -26.662 17.672  2.755   1   66.24  ? 207 THR B OG1 1 
ATOM   4810 C  CG2 . THR C 1 37  ? -28.198 18.672  4.321   1   62.2   ? 207 THR B CG2 1 
ATOM   4811 N  N   . ASN C 1 38  ? -28.271 14.659  2.307   1   55.61  ? 208 ASN B N   1 
ATOM   4812 C  CA  . ASN C 1 38  ? -27.92  13.655  1.274   1   55.32  ? 208 ASN B CA  1 
ATOM   4813 C  C   . ASN C 1 38  ? -26.838 14.256  0.378   1   54.31  ? 208 ASN B C   1 
ATOM   4814 O  O   . ASN C 1 38  ? -25.914 13.526  -0.001  1   51.22  ? 208 ASN B O   1 
ATOM   4815 C  CB  . ASN C 1 38  ? -29.15  13.242  0.48    1   56.98  ? 208 ASN B CB  1 
ATOM   4816 C  CG  . ASN C 1 38  ? -30.145 12.45   1.289   1   60.79  ? 208 ASN B CG  1 
ATOM   4817 O  OD1 . ASN C 1 38  ? -29.759 11.568  2.06    1   64.34  ? 208 ASN B OD1 1 
ATOM   4818 N  ND2 . ASN C 1 38  ? -31.426 12.735  1.116   1   57.6   ? 208 ASN B ND2 1 
ATOM   4819 N  N   . SER C 1 39  ? -26.966 15.537  0.044   1   56.97  ? 209 SER B N   1 
ATOM   4820 C  CA  . SER C 1 39  ? -25.966 16.237  -0.745  1   59.37  ? 209 SER B CA  1 
ATOM   4821 C  C   . SER C 1 39  ? -24.577 16.134  -0.104  1   59     ? 209 SER B C   1 
ATOM   4822 O  O   . SER C 1 39  ? -23.598 15.895  -0.814  1   59.66  ? 209 SER B O   1 
ATOM   4823 C  CB  . SER C 1 39  ? -26.402 17.651  -1.018  1   64.17  ? 209 SER B CB  1 
ATOM   4824 O  OG  . SER C 1 39  ? -26.509 18.416  0.177   1   67.48  ? 209 SER B OG  1 
ATOM   4825 N  N   . MET C 1 40  ? -24.509 16.327  1.216   1   56.5   ? 210 MET B N   1 
ATOM   4826 C  CA  . MET C 1 40  ? -23.214 16.218  1.937   1   54.59  ? 210 MET B CA  1 
ATOM   4827 C  C   . MET C 1 40  ? -22.71  14.773  1.827   1   51.88  ? 210 MET B C   1 
ATOM   4828 O  O   . MET C 1 40  ? -21.517 14.58   1.508   1   52.63  ? 210 MET B O   1 
ATOM   4829 C  CB  . MET C 1 40  ? -23.378 16.587  3.414   1   55.63  ? 210 MET B CB  1 
ATOM   4830 C  CG  . MET C 1 40  ? -23.435 18.079  3.667   1   58.37  ? 210 MET B CG  1 
ATOM   4831 S  SD  . MET C 1 40  ? -23.429 18.491  5.422   1   60.78  ? 210 MET B SD  1 
ATOM   4832 C  CE  . MET C 1 40  ? -24.551 19.896  5.42    1   60.44  ? 210 MET B CE  1 
ATOM   4833 N  N   . ARG C 1 41  ? -23.592 13.803  2.08    1   49.11  ? 211 ARG B N   1 
ATOM   4834 C  CA  . ARG C 1 41  ? -23.21  12.372  1.963   1   47.35  ? 211 ARG B CA  1 
ATOM   4835 C  C   . ARG C 1 41  ? -22.643 12.124  0.558   1   47.79  ? 211 ARG B C   1 
ATOM   4836 O  O   . ARG C 1 41  ? -21.585 11.471  0.45    1   45.43  ? 211 ARG B O   1 
ATOM   4837 C  CB  . ARG C 1 41  ? -24.429 11.487  2.236   1   47.92  ? 211 ARG B CB  1 
ATOM   4838 C  CG  . ARG C 1 41  ? -24.119 9.999   2.303   1   47.42  ? 211 ARG B CG  1 
ATOM   4839 C  CD  . ARG C 1 41  ? -25.388 9.173   2.195   1   48.07  ? 211 ARG B CD  1 
ATOM   4840 N  NE  . ARG C 1 41  ? -25.126 7.794   1.77    1   48.84  ? 211 ARG B NE  1 
ATOM   4841 C  CZ  . ARG C 1 41  ? -25.233 7.365   0.52    1   49.39  ? 211 ARG B CZ  1 
ATOM   4842 N  NH1 . ARG C 1 41  ? -25.232 8.23    -0.477  1   48.93  ? 211 ARG B NH1 1 
ATOM   4843 N  NH2 . ARG C 1 41  ? -25.337 6.072   0.272   1   45.3   ? 211 ARG B NH2 1 
ATOM   4844 N  N   . ALA C 1 42  ? -23.325 12.63   -0.473  1   50.29  ? 212 ALA B N   1 
ATOM   4845 C  CA  . ALA C 1 42  ? -22.83  12.474  -1.861  1   46.67  ? 212 ALA B CA  1 
ATOM   4846 C  C   . ALA C 1 42  ? -21.38  12.949  -1.945  1   47.5   ? 212 ALA B C   1 
ATOM   4847 O  O   . ALA C 1 42  ? -20.535 12.196  -2.474  1   47.65  ? 212 ALA B O   1 
ATOM   4848 C  CB  . ALA C 1 42  ? -23.719 13.241  -2.813  1   44.18  ? 212 ALA B CB  1 
ATOM   4849 N  N   . ILE C 1 43  ? -21.095 14.152  -1.433  1   47.38  ? 213 ILE B N   1 
ATOM   4850 C  CA  . ILE C 1 43  ? -19.754 14.69   -1.534  1   47.79  ? 213 ILE B CA  1 
ATOM   4851 C  C   . ILE C 1 43  ? -18.766 13.726  -0.884  1   48.83  ? 213 ILE B C   1 
ATOM   4852 O  O   . ILE C 1 43  ? -17.69  13.481  -1.438  1   50.08  ? 213 ILE B O   1 
ATOM   4853 C  CB  . ILE C 1 43  ? -19.692 16.099  -0.935  1   49.19  ? 213 ILE B CB  1 
ATOM   4854 C  CG1 . ILE C 1 43  ? -20.462 17.111  -1.829  1   47.89  ? 213 ILE B CG1 1 
ATOM   4855 C  CG2 . ILE C 1 43  ? -18.235 16.507  -0.66   1   48.52  ? 213 ILE B CG2 1 
ATOM   4856 C  CD1 . ILE C 1 43  ? -20.688 18.455  -1.168  1   48.57  ? 213 ILE B CD1 1 
ATOM   4857 N  N   . LEU C 1 44  ? -19.158 13.155  0.266   1   46.1   ? 214 LEU B N   1 
ATOM   4858 C  CA  . LEU C 1 44  ? -18.291 12.232  0.976   1   45.89  ? 214 LEU B CA  1 
ATOM   4859 C  C   . LEU C 1 44  ? -18.018 10.977  0.153   1   46.96  ? 214 LEU B C   1 
ATOM   4860 O  O   . LEU C 1 44  ? -16.872 10.538  0.017   1   48.05  ? 214 LEU B O   1 
ATOM   4861 C  CB  . LEU C 1 44  ? -18.911 11.862  2.316   1   44.48  ? 214 LEU B CB  1 
ATOM   4862 C  CG  . LEU C 1 44  ? -18.162 10.812  3.146   1   42.1   ? 214 LEU B CG  1 
ATOM   4863 C  CD1 . LEU C 1 44  ? -16.862 11.364  3.684   1   42.23  ? 214 LEU B CD1 1 
ATOM   4864 C  CD2 . LEU C 1 44  ? -19.047 10.345  4.301   1   40.18  ? 214 LEU B CD2 1 
ATOM   4865 N  N   . VAL C 1 45  ? -19.088 10.377  -0.365  1   46.71  ? 215 VAL B N   1 
ATOM   4866 C  CA  . VAL C 1 45  ? -18.937 9.125   -1.079  1   46.72  ? 215 VAL B CA  1 
ATOM   4867 C  C   . VAL C 1 45  ? -18.097 9.349   -2.339  1   50.04  ? 215 VAL B C   1 
ATOM   4868 O  O   . VAL C 1 45  ? -17.304 8.496   -2.744  1   51.4   ? 215 VAL B O   1 
ATOM   4869 C  CB  . VAL C 1 45  ? -20.309 8.486   -1.353  1   43.97  ? 215 VAL B CB  1 
ATOM   4870 C  CG1 . VAL C 1 45  ? -20.15  7.24    -2.187  1   45.06  ? 215 VAL B CG1 1 
ATOM   4871 C  CG2 . VAL C 1 45  ? -21.011 8.116   -0.041  1   43     ? 215 VAL B CG2 1 
ATOM   4872 N  N   . ASP C 1 46  ? -18.262 10.514  -2.964  1   50.1   ? 216 ASP B N   1 
ATOM   4873 C  CA  . ASP C 1 46  ? -17.507 10.835  -4.162  1   49.66  ? 216 ASP B CA  1 
ATOM   4874 C  C   . ASP C 1 46  ? -16.026 10.93   -3.812  1   49.85  ? 216 ASP B C   1 
ATOM   4875 O  O   . ASP C 1 46  ? -15.173 10.49   -4.587  1   52.74  ? 216 ASP B O   1 
ATOM   4876 C  CB  . ASP C 1 46  ? -18.04  12.111  -4.792  1   50.94  ? 216 ASP B CB  1 
ATOM   4877 C  CG  . ASP C 1 46  ? -17.336 12.551  -6.06   1   51.58  ? 216 ASP B CG  1 
ATOM   4878 O  OD1 . ASP C 1 46  ? -17.711 12.068  -7.153  1   52.79  ? 216 ASP B OD1 1 
ATOM   4879 O  OD2 . ASP C 1 46  ? -16.384 13.331  -5.928  1   53.55  ? 216 ASP B OD2 1 
ATOM   4880 N  N   . TRP C 1 47  ? -15.732 11.538  -2.654  1   49.07  ? 217 TRP B N   1 
ATOM   4881 C  CA  . TRP C 1 47  ? -14.361 11.673  -2.184  1   50.82  ? 217 TRP B CA  1 
ATOM   4882 C  C   . TRP C 1 47  ? -13.749 10.294  -1.912  1   50.97  ? 217 TRP B C   1 
ATOM   4883 O  O   . TRP C 1 47  ? -12.574 10.071  -2.186  1   52.68  ? 217 TRP B O   1 
ATOM   4884 C  CB  . TRP C 1 47  ? -14.305 12.625  -0.978  1   49.7   ? 217 TRP B CB  1 
ATOM   4885 C  CG  . TRP C 1 47  ? -12.967 12.709  -0.295  1   48.7   ? 217 TRP B CG  1 
ATOM   4886 C  CD1 . TRP C 1 47  ? -11.867 13.384  -0.731  1   50.24  ? 217 TRP B CD1 1 
ATOM   4887 C  CD2 . TRP C 1 47  ? -12.585 12.1    0.956   1   46.73  ? 217 TRP B CD2 1 
ATOM   4888 N  NE1 . TRP C 1 47  ? -10.83  13.241  0.157   1   49.54  ? 217 TRP B NE1 1 
ATOM   4889 C  CE2 . TRP C 1 47  ? -11.24  12.462  1.201   1   47.56  ? 217 TRP B CE2 1 
ATOM   4890 C  CE3 . TRP C 1 47  ? -13.241 11.294  1.89    1   47.14  ? 217 TRP B CE3 1 
ATOM   4891 C  CZ2 . TRP C 1 47  ? -10.541 12.036  2.324   1   47.17  ? 217 TRP B CZ2 1 
ATOM   4892 C  CZ3 . TRP C 1 47  ? -12.548 10.856  3.004   1   45.81  ? 217 TRP B CZ3 1 
ATOM   4893 C  CH2 . TRP C 1 47  ? -11.217 11.219  3.204   1   47.35  ? 217 TRP B CH2 1 
ATOM   4894 N  N   . LEU C 1 48  ? -14.563 9.355   -1.415  1   50.34  ? 218 LEU B N   1 
ATOM   4895 C  CA  . LEU C 1 48  ? -14.089 8.017   -1.088  1   49.03  ? 218 LEU B CA  1 
ATOM   4896 C  C   . LEU C 1 48  ? -13.727 7.292   -2.374  1   46.61  ? 218 LEU B C   1 
ATOM   4897 O  O   . LEU C 1 48  ? -12.805 6.489   -2.387  1   47.66  ? 218 LEU B O   1 
ATOM   4898 C  CB  . LEU C 1 48  ? -15.105 7.228   -0.26   1   46.17  ? 218 LEU B CB  1 
ATOM   4899 C  CG  . LEU C 1 48  ? -15.338 7.739   1.168   1   46.35  ? 218 LEU B CG  1 
ATOM   4900 C  CD1 . LEU C 1 48  ? -16.453 6.998   1.878   1   43.53  ? 218 LEU B CD1 1 
ATOM   4901 C  CD2 . LEU C 1 48  ? -14.056 7.626   1.976   1   44.32  ? 218 LEU B CD2 1 
ATOM   4902 N  N   . VAL C 1 49  ? -14.461 7.602   -3.44   1   44.7   ? 219 VAL B N   1 
ATOM   4903 C  CA  . VAL C 1 49  ? -14.193 7.02    -4.737  1   44.7   ? 219 VAL B CA  1 
ATOM   4904 C  C   . VAL C 1 49  ? -12.798 7.469   -5.166  1   48.9   ? 219 VAL B C   1 
ATOM   4905 O  O   . VAL C 1 49  ? -11.985 6.631   -5.553  1   49.97  ? 219 VAL B O   1 
ATOM   4906 C  CB  . VAL C 1 49  ? -15.285 7.35    -5.775  1   43.08  ? 219 VAL B CB  1 
ATOM   4907 C  CG1 . VAL C 1 49  ? -14.849 7.068   -7.203  1   46.08  ? 219 VAL B CG1 1 
ATOM   4908 C  CG2 . VAL C 1 49  ? -16.555 6.574   -5.503  1   43.43  ? 219 VAL B CG2 1 
ATOM   4909 N  N   . GLU C 1 50  ? -12.528 8.78    -5.071  1   52.4   ? 220 GLU B N   1 
ATOM   4910 C  CA  . GLU C 1 50  ? -11.211 9.323   -5.363  1   55.71  ? 220 GLU B CA  1 
ATOM   4911 C  C   . GLU C 1 50  ? -10.141 8.683   -4.477  1   56.6   ? 220 GLU B C   1 
ATOM   4912 O  O   . GLU C 1 50  ? -9.038  8.403   -4.934  1   61.59  ? 220 GLU B O   1 
ATOM   4913 C  CB  . GLU C 1 50  ? -11.147 10.828  -5.131  1   58.62  ? 220 GLU B CB  1 
ATOM   4914 C  CG  . GLU C 1 50  ? -11.744 11.619  -6.282  1   70     ? 220 GLU B CG  1 
ATOM   4915 C  CD  . GLU C 1 50  ? -11.668 13.121  -6.12   1   80.15  ? 220 GLU B CD  1 
ATOM   4916 O  OE1 . GLU C 1 50  ? -11.352 13.808  -7.129  1   89.46  ? 220 GLU B OE1 1 
ATOM   4917 O  OE2 . GLU C 1 50  ? -11.926 13.59   -4.984  1   84.38  ? 220 GLU B OE2 1 
ATOM   4918 N  N   . VAL C 1 51  ? -10.436 8.506   -3.19   1   53.18  ? 221 VAL B N   1 
ATOM   4919 C  CA  . VAL C 1 51  ? -9.447  7.923   -2.307  1   51.45  ? 221 VAL B CA  1 
ATOM   4920 C  C   . VAL C 1 51  ? -9.107  6.502   -2.77   1   50.97  ? 221 VAL B C   1 
ATOM   4921 O  O   . VAL C 1 51  ? -7.925  6.172   -2.87   1   50.22  ? 221 VAL B O   1 
ATOM   4922 C  CB  . VAL C 1 51  ? -9.864  8.021   -0.829  1   50.1   ? 221 VAL B CB  1 
ATOM   4923 C  CG1 . VAL C 1 51  ? -8.955  7.208   0.077   1   48.45  ? 221 VAL B CG1 1 
ATOM   4924 C  CG2 . VAL C 1 51  ? -9.855  9.464   -0.354  1   49.52  ? 221 VAL B CG2 1 
ATOM   4925 N  N   . GLY C 1 52  ? -10.127 5.678   -3.07   1   46.96  ? 222 GLY B N   1 
ATOM   4926 C  CA  . GLY C 1 52  ? -9.909  4.331   -3.583  1   46.18  ? 222 GLY B CA  1 
ATOM   4927 C  C   . GLY C 1 52  ? -9.094  4.284   -4.89   1   54.63  ? 222 GLY B C   1 
ATOM   4928 O  O   . GLY C 1 52  ? -8.344  3.337   -5.131  1   55.93  ? 222 GLY B O   1 
ATOM   4929 N  N   . GLU C 1 53  ? -9.232  5.29    -5.763  1   57.95  ? 223 GLU B N   1 
ATOM   4930 C  CA  . GLU C 1 53  ? -8.457  5.335   -6.998  1   62.08  ? 223 GLU B CA  1 
ATOM   4931 C  C   . GLU C 1 53  ? -7.015  5.743   -6.712  1   61.9   ? 223 GLU B C   1 
ATOM   4932 O  O   . GLU C 1 53  ? -6.085  5.126   -7.194  1   68.32  ? 223 GLU B O   1 
ATOM   4933 C  CB  . GLU C 1 53  ? -9.089  6.264   -8.029  1   66.97  ? 223 GLU B CB  1 
ATOM   4934 C  CG  . GLU C 1 53  ? -10.315 5.625   -8.668  1   78.14  ? 223 GLU B CG  1 
ATOM   4935 C  CD  . GLU C 1 53  ? -9.932  4.521   -9.645  1   100.2  ? 223 GLU B CD  1 
ATOM   4936 O  OE1 . GLU C 1 53  ? -10.147 3.302   -9.345  1   92.49  ? 223 GLU B OE1 1 
ATOM   4937 O  OE2 . GLU C 1 53  ? -9.426  4.912   -10.739 1   106.95 ? 223 GLU B OE2 1 
ATOM   4938 N  N   . GLU C 1 54  ? -6.828  6.775   -5.895  1   63.63  ? 224 GLU B N   1 
ATOM   4939 C  CA  . GLU C 1 54  ? -5.514  7.179   -5.425  1   62.74  ? 224 GLU B CA  1 
ATOM   4940 C  C   . GLU C 1 54  ? -4.772  5.967   -4.844  1   59.91  ? 224 GLU B C   1 
ATOM   4941 O  O   . GLU C 1 54  ? -3.626  5.735   -5.197  1   61.47  ? 224 GLU B O   1 
ATOM   4942 C  CB  . GLU C 1 54  ? -5.716  8.367   -4.479  1   65.08  ? 224 GLU B CB  1 
ATOM   4943 C  CG  . GLU C 1 54  ? -4.447  8.876   -3.804  1   73.46  ? 224 GLU B CG  1 
ATOM   4944 C  CD  . GLU C 1 54  ? -3.666  9.89    -4.627  1   82.42  ? 224 GLU B CD  1 
ATOM   4945 O  OE1 . GLU C 1 54  ? -4.005  10.063  -5.818  1   90.7   ? 224 GLU B OE1 1 
ATOM   4946 O  OE2 . GLU C 1 54  ? -2.735  10.519  -4.084  1   84.86  ? 224 GLU B OE2 1 
ATOM   4947 N  N   . TYR C 1 55  ? -5.412  5.185   -3.967  1   56.13  ? 225 TYR B N   1 
ATOM   4948 C  CA  . TYR C 1 55  ? -4.705  4.138   -3.24   1   55.5   ? 225 TYR B CA  1 
ATOM   4949 C  C   . TYR C 1 55  ? -4.885  2.776   -3.896  1   54.93  ? 225 TYR B C   1 
ATOM   4950 O  O   . TYR C 1 55  ? -4.361  1.782   -3.389  1   54.73  ? 225 TYR B O   1 
ATOM   4951 C  CB  . TYR C 1 55  ? -5.062  4.139   -1.753  1   52.95  ? 225 TYR B CB  1 
ATOM   4952 C  CG  . TYR C 1 55  ? -4.404  5.316   -1.056  1   57.88  ? 225 TYR B CG  1 
ATOM   4953 C  CD1 . TYR C 1 55  ? -3.107  5.232   -0.546  1   55.81  ? 225 TYR B CD1 1 
ATOM   4954 C  CD2 . TYR C 1 55  ? -5.039  6.558   -1.042  1   61.98  ? 225 TYR B CD2 1 
ATOM   4955 C  CE1 . TYR C 1 55  ? -2.504  6.336   0.033   1   58.57  ? 225 TYR B CE1 1 
ATOM   4956 C  CE2 . TYR C 1 55  ? -4.447  7.663   -0.449  1   61.83  ? 225 TYR B CE2 1 
ATOM   4957 C  CZ  . TYR C 1 55  ? -3.182  7.544   0.098   1   60.07  ? 225 TYR B CZ  1 
ATOM   4958 O  OH  . TYR C 1 55  ? -2.647  8.65    0.674   1   63.56  ? 225 TYR B OH  1 
ATOM   4959 N  N   . LYS C 1 56  ? -5.607  2.753   -5.024  1   53.82  ? 226 LYS B N   1 
ATOM   4960 C  CA  . LYS C 1 56  ? -5.794  1.533   -5.785  1   53.71  ? 226 LYS B CA  1 
ATOM   4961 C  C   . LYS C 1 56  ? -6.411  0.465   -4.882  1   54.21  ? 226 LYS B C   1 
ATOM   4962 O  O   . LYS C 1 56  ? -5.93   -0.665  -4.842  1   57.64  ? 226 LYS B O   1 
ATOM   4963 C  CB  . LYS C 1 56  ? -4.459  1.104   -6.398  1   53.28  ? 226 LYS B CB  1 
ATOM   4964 C  CG  . LYS C 1 56  ? -3.898  2.212   -7.245  1   59.17  ? 226 LYS B CG  1 
ATOM   4965 C  CD  . LYS C 1 56  ? -2.716  1.854   -8.126  1   67.78  ? 226 LYS B CD  1 
ATOM   4966 C  CE  . LYS C 1 56  ? -2.34   3.048   -8.954  1   75.86  ? 226 LYS B CE  1 
ATOM   4967 N  NZ  . LYS C 1 56  ? -0.91   2.977   -9.29   1   88.42  ? 226 LYS B NZ  1 
ATOM   4968 N  N   . LEU C 1 57  ? -7.485  0.841   -4.17   1   49.31  ? 227 LEU B N   1 
ATOM   4969 C  CA  . LEU C 1 57  ? -8.241  -0.08   -3.341  1   45.68  ? 227 LEU B CA  1 
ATOM   4970 C  C   . LEU C 1 57  ? -9.211  -0.876  -4.209  1   45.76  ? 227 LEU B C   1 
ATOM   4971 O  O   . LEU C 1 57  ? -9.585  -0.458  -5.292  1   49.07  ? 227 LEU B O   1 
ATOM   4972 C  CB  . LEU C 1 57  ? -8.967  0.739   -2.279  1   42.06  ? 227 LEU B CB  1 
ATOM   4973 C  CG  . LEU C 1 57  ? -8.04   1.572   -1.393  1   43.13  ? 227 LEU B CG  1 
ATOM   4974 C  CD1 . LEU C 1 57  ? -8.857  2.322   -0.372  1   43.69  ? 227 LEU B CD1 1 
ATOM   4975 C  CD2 . LEU C 1 57  ? -6.988  0.704   -0.715  1   39.56  ? 227 LEU B CD2 1 
ATOM   4976 N  N   . GLN C 1 58  ? -9.616  -2.04   -3.716  1   44.4   ? 228 GLN B N   1 
ATOM   4977 C  CA  . GLN C 1 58  ? -10.633 -2.815  -4.385  1   43.68  ? 228 GLN B CA  1 
ATOM   4978 C  C   . GLN C 1 58  ? -11.901 -1.979  -4.389  1   46.62  ? 228 GLN B C   1 
ATOM   4979 O  O   . GLN C 1 58  ? -12.09  -1.122  -3.518  1   51.06  ? 228 GLN B O   1 
ATOM   4980 C  CB  . GLN C 1 58  ? -10.865 -4.112  -3.6    1   45.42  ? 228 GLN B CB  1 
ATOM   4981 C  CG  . GLN C 1 58  ? -9.694  -5.092  -3.628  1   48.5   ? 228 GLN B CG  1 
ATOM   4982 C  CD  . GLN C 1 58  ? -9.345  -5.521  -5.037  1   47.85  ? 228 GLN B CD  1 
ATOM   4983 O  OE1 . GLN C 1 58  ? -10.137 -6.134  -5.759  1   53.64  ? 228 GLN B OE1 1 
ATOM   4984 N  NE2 . GLN C 1 58  ? -8.164  -5.144  -5.467  1   45.38  ? 228 GLN B NE2 1 
ATOM   4985 N  N   . ASN C 1 59  ? -12.785 -2.272  -5.347  1   47.9   ? 229 ASN B N   1 
ATOM   4986 C  CA  . ASN C 1 59  ? -14.125 -1.695  -5.35   1   46.82  ? 229 ASN B CA  1 
ATOM   4987 C  C   . ASN C 1 59  ? -14.918 -2.204  -4.139  1   45.38  ? 229 ASN B C   1 
ATOM   4988 O  O   . ASN C 1 59  ? -15.713 -1.478  -3.543  1   53.52  ? 229 ASN B O   1 
ATOM   4989 C  CB  . ASN C 1 59  ? -14.837 -1.916  -6.687  1   47.73  ? 229 ASN B CB  1 
ATOM   4990 C  CG  . ASN C 1 59  ? -14.244 -1.115  -7.826  1   49.35  ? 229 ASN B CG  1 
ATOM   4991 O  OD1 . ASN C 1 59  ? -13.308 -0.333  -7.641  1   51.29  ? 229 ASN B OD1 1 
ATOM   4992 N  ND2 . ASN C 1 59  ? -14.782 -1.287  -9.019  1   52.11  ? 229 ASN B ND2 1 
ATOM   4993 N  N   . GLU C 1 60  ? -14.712 -3.469  -3.768  1   42.3   ? 230 GLU B N   1 
ATOM   4994 C  CA  . GLU C 1 60  ? -15.428 -4.062  -2.651  1   38.2   ? 230 GLU B CA  1 
ATOM   4995 C  C   . GLU C 1 60  ? -15.196 -3.238  -1.385  1   38.14  ? 230 GLU B C   1 
ATOM   4996 O  O   . GLU C 1 60  ? -16.101 -3.103  -0.557  1   36.24  ? 230 GLU B O   1 
ATOM   4997 C  CB  . GLU C 1 60  ? -14.924 -5.496  -2.526  1   37.22  ? 230 GLU B CB  1 
ATOM   4998 C  CG  . GLU C 1 60  ? -15.513 -6.272  -1.359  1   37.54  ? 230 GLU B CG  1 
ATOM   4999 C  CD  . GLU C 1 60  ? -17.006 -6.456  -1.488  1   39.34  ? 230 GLU B CD  1 
ATOM   5000 O  OE1 . GLU C 1 60  ? -17.534 -6.357  -2.612  1   39.89  ? 230 GLU B OE1 1 
ATOM   5001 O  OE2 . GLU C 1 60  ? -17.627 -6.644  -0.423  1   42.11  ? 230 GLU B OE2 1 
ATOM   5002 N  N   . THR C 1 61  ? -13.969 -2.717  -1.23   1   37.73  ? 231 THR B N   1 
ATOM   5003 C  CA  . THR C 1 61  ? -13.595 -1.947  -0.059  1   39.11  ? 231 THR B CA  1 
ATOM   5004 C  C   . THR C 1 61  ? -14.45  -0.677  -0.001  1   45.04  ? 231 THR B C   1 
ATOM   5005 O  O   . THR C 1 61  ? -15.018 -0.362  1.055   1   43.36  ? 231 THR B O   1 
ATOM   5006 C  CB  . THR C 1 61  ? -12.111 -1.607  -0.125  1   41.19  ? 231 THR B CB  1 
ATOM   5007 O  OG1 . THR C 1 61  ? -11.373 -2.812  -0.274  1   41.04  ? 231 THR B OG1 1 
ATOM   5008 C  CG2 . THR C 1 61  ? -11.636 -0.873  1.118   1   43.63  ? 231 THR B CG2 1 
ATOM   5009 N  N   . LEU C 1 62  ? -14.512 0.046   -1.14   1   45.03  ? 232 LEU B N   1 
ATOM   5010 C  CA  . LEU C 1 62  ? -15.368 1.21    -1.289  1   43.06  ? 232 LEU B CA  1 
ATOM   5011 C  C   . LEU C 1 62  ? -16.818 0.889   -0.872  1   41.35  ? 232 LEU B C   1 
ATOM   5012 O  O   . LEU C 1 62  ? -17.384 1.589   -0.033  1   42.81  ? 232 LEU B O   1 
ATOM   5013 C  CB  . LEU C 1 62  ? -15.274 1.768   -2.706  1   42.27  ? 232 LEU B CB  1 
ATOM   5014 C  CG  . LEU C 1 62  ? -16.397 2.757   -3.055  1   44.44  ? 232 LEU B CG  1 
ATOM   5015 C  CD1 . LEU C 1 62  ? -16.228 3.996   -2.192  1   43.99  ? 232 LEU B CD1 1 
ATOM   5016 C  CD2 . LEU C 1 62  ? -16.511 3.15    -4.507  1   41.28  ? 232 LEU B CD2 1 
ATOM   5017 N  N   . HIS C 1 63  ? -17.427 -0.15   -1.453  1   36.32  ? 233 HIS B N   1 
ATOM   5018 C  CA  . HIS C 1 63  ? -18.789 -0.55   -1.082  1   36.71  ? 233 HIS B CA  1 
ATOM   5019 C  C   . HIS C 1 63  ? -18.95  -0.886  0.412   1   39.41  ? 233 HIS B C   1 
ATOM   5020 O  O   . HIS C 1 63  ? -19.959 -0.506  1.016   1   41.25  ? 233 HIS B O   1 
ATOM   5021 C  CB  . HIS C 1 63  ? -19.284 -1.746  -1.897  1   34.38  ? 233 HIS B CB  1 
ATOM   5022 C  CG  . HIS C 1 63  ? -19.719 -1.447  -3.296  1   37.99  ? 233 HIS B CG  1 
ATOM   5023 N  ND1 . HIS C 1 63  ? -18.855 -1.221  -4.352  1   39.43  ? 233 HIS B ND1 1 
ATOM   5024 C  CD2 . HIS C 1 63  ? -20.955 -1.35   -3.802  1   35.85  ? 233 HIS B CD2 1 
ATOM   5025 C  CE1 . HIS C 1 63  ? -19.574 -0.988  -5.443  1   38.42  ? 233 HIS B CE1 1 
ATOM   5026 N  NE2 . HIS C 1 63  ? -20.847 -1.064  -5.121  1   36.51  ? 233 HIS B NE2 1 
ATOM   5027 N  N   . LEU C 1 64  ? -17.987 -1.605  1.02    1   37.06  ? 234 LEU B N   1 
ATOM   5028 C  CA  . LEU C 1 64  ? -18.035 -1.856  2.452   1   36.22  ? 234 LEU B CA  1 
ATOM   5029 C  C   . LEU C 1 64  ? -18.045 -0.518  3.197   1   39.12  ? 234 LEU B C   1 
ATOM   5030 O  O   . LEU C 1 64  ? -18.817 -0.34   4.133   1   38.84  ? 234 LEU B O   1 
ATOM   5031 C  CB  . LEU C 1 64  ? -16.844 -2.716  2.888   1   35.22  ? 234 LEU B CB  1 
ATOM   5032 C  CG  . LEU C 1 64  ? -16.82  -4.171  2.412   1   33.53  ? 234 LEU B CG  1 
ATOM   5033 C  CD1 . LEU C 1 64  ? -15.477 -4.777  2.722   1   31.81  ? 234 LEU B CD1 1 
ATOM   5034 C  CD2 . LEU C 1 64  ? -17.963 -5.018  2.969   1   31.55  ? 234 LEU B CD2 1 
ATOM   5035 N  N   . ALA C 1 65  ? -17.186 0.428   2.79    1   40.43  ? 235 ALA B N   1 
ATOM   5036 C  CA  . ALA C 1 65  ? -17.069 1.698   3.498   1   41.66  ? 235 ALA B CA  1 
ATOM   5037 C  C   . ALA C 1 65  ? -18.417 2.427   3.568   1   44.51  ? 235 ALA B C   1 
ATOM   5038 O  O   . ALA C 1 65  ? -18.788 3.014   4.593   1   46.71  ? 235 ALA B O   1 
ATOM   5039 C  CB  . ALA C 1 65  ? -16.017 2.574   2.834   1   39.51  ? 235 ALA B CB  1 
ATOM   5040 N  N   . VAL C 1 66  ? -19.121 2.472   2.437   1   42.54  ? 236 VAL B N   1 
ATOM   5041 C  CA  . VAL C 1 66  ? -20.403 3.149   2.409   1   43.61  ? 236 VAL B CA  1 
ATOM   5042 C  C   . VAL C 1 66  ? -21.39  2.378   3.301   1   44.35  ? 236 VAL B C   1 
ATOM   5043 O  O   . VAL C 1 66  ? -22.131 2.992   4.061   1   45.33  ? 236 VAL B O   1 
ATOM   5044 C  CB  . VAL C 1 66  ? -20.879 3.307   0.95    1   42.06  ? 236 VAL B CB  1 
ATOM   5045 C  CG1 . VAL C 1 66  ? -22.258 3.95    0.881   1   42.68  ? 236 VAL B CG1 1 
ATOM   5046 C  CG2 . VAL C 1 66  ? -19.874 4.09    0.119   1   39.83  ? 236 VAL B CG2 1 
ATOM   5047 N  N   . ASN C 1 67  ? -21.37  1.033   3.258   1   42.31  ? 237 ASN B N   1 
ATOM   5048 C  CA  . ASN C 1 67  ? -22.214 0.237   4.144   1   41.45  ? 237 ASN B CA  1 
ATOM   5049 C  C   . ASN C 1 67  ? -22.01  0.671   5.602   1   42.68  ? 237 ASN B C   1 
ATOM   5050 O  O   . ASN C 1 67  ? -22.985 0.831   6.352   1   41.02  ? 237 ASN B O   1 
ATOM   5051 C  CB  . ASN C 1 67  ? -22.008 -1.27   3.972   1   37.81  ? 237 ASN B CB  1 
ATOM   5052 C  CG  . ASN C 1 67  ? -22.821 -2.008  5.005   1   42.02  ? 237 ASN B CG  1 
ATOM   5053 O  OD1 . ASN C 1 67  ? -22.342 -2.297  6.106   1   50.11  ? 237 ASN B OD1 1 
ATOM   5054 N  ND2 . ASN C 1 67  ? -24.102 -2.188  4.745   1   44.02  ? 237 ASN B ND2 1 
ATOM   5055 N  N   . TYR C 1 68  ? -20.732 0.831   6.004   1   39.74  ? 238 TYR B N   1 
ATOM   5056 C  CA  . TYR C 1 68  ? -20.405 1.16    7.382   1   41.56  ? 238 TYR B CA  1 
ATOM   5057 C  C   . TYR C 1 68  ? -20.894 2.565   7.734   1   41.83  ? 238 TYR B C   1 
ATOM   5058 O  O   . TYR C 1 68  ? -21.396 2.8     8.837   1   40.38  ? 238 TYR B O   1 
ATOM   5059 C  CB  . TYR C 1 68  ? -18.907 1.072   7.673   1   43.25  ? 238 TYR B CB  1 
ATOM   5060 C  CG  . TYR C 1 68  ? -18.3   -0.297  7.426   1   41.62  ? 238 TYR B CG  1 
ATOM   5061 C  CD1 . TYR C 1 68  ? -19.091 -1.431  7.209   1   41.15  ? 238 TYR B CD1 1 
ATOM   5062 C  CD2 . TYR C 1 68  ? -16.926 -0.434  7.375   1   39.77  ? 238 TYR B CD2 1 
ATOM   5063 C  CE1 . TYR C 1 68  ? -18.526 -2.674  6.967   1   38.95  ? 238 TYR B CE1 1 
ATOM   5064 C  CE2 . TYR C 1 68  ? -16.355 -1.661  7.109   1   40.17  ? 238 TYR B CE2 1 
ATOM   5065 C  CZ  . TYR C 1 68  ? -17.149 -2.779  6.919   1   39.39  ? 238 TYR B CZ  1 
ATOM   5066 O  OH  . TYR C 1 68  ? -16.511 -3.961  6.68    1   43.92  ? 238 TYR B OH  1 
ATOM   5067 N  N   . ILE C 1 69  ? -20.705 3.484   6.781   1   39.61  ? 239 ILE B N   1 
ATOM   5068 C  CA  . ILE C 1 69  ? -21.047 4.88    6.966   1   40.46  ? 239 ILE B CA  1 
ATOM   5069 C  C   . ILE C 1 69  ? -22.548 4.981   7.17    1   42.33  ? 239 ILE B C   1 
ATOM   5070 O  O   . ILE C 1 69  ? -22.984 5.656   8.111   1   43.01  ? 239 ILE B O   1 
ATOM   5071 C  CB  . ILE C 1 69  ? -20.573 5.753   5.787   1   39.7   ? 239 ILE B CB  1 
ATOM   5072 C  CG1 . ILE C 1 69  ? -19.052 5.855   5.702   1   38.38  ? 239 ILE B CG1 1 
ATOM   5073 C  CG2 . ILE C 1 69  ? -21.226 7.129   5.841   1   37.5   ? 239 ILE B CG2 1 
ATOM   5074 C  CD1 . ILE C 1 69  ? -18.566 6.553   4.451   1   37.36  ? 239 ILE B CD1 1 
ATOM   5075 N  N   . ASP C 1 70  ? -23.311 4.314   6.289   1   42.01  ? 240 ASP B N   1 
ATOM   5076 C  CA  . ASP C 1 70  ? -24.766 4.409   6.326   1   45.9   ? 240 ASP B CA  1 
ATOM   5077 C  C   . ASP C 1 70  ? -25.316 3.774   7.61    1   47.97  ? 240 ASP B C   1 
ATOM   5078 O  O   . ASP C 1 70  ? -26.224 4.33    8.223   1   49.65  ? 240 ASP B O   1 
ATOM   5079 C  CB  . ASP C 1 70  ? -25.419 3.837   5.079   1   47.47  ? 240 ASP B CB  1 
ATOM   5080 C  CG  . ASP C 1 70  ? -25.25  4.624   3.785   1   51.45  ? 240 ASP B CG  1 
ATOM   5081 O  OD1 . ASP C 1 70  ? -25.234 5.883   3.846   1   50.34  ? 240 ASP B OD1 1 
ATOM   5082 O  OD2 . ASP C 1 70  ? -25.197 3.969   2.715   1   51.69  ? 240 ASP B OD2 1 
ATOM   5083 N  N   . ARG C 1 71  ? -24.749 2.635   8.043   1   43.81  ? 241 ARG B N   1 
ATOM   5084 C  CA  . ARG C 1 71  ? -25.225 2.02    9.269   1   42.07  ? 241 ARG B CA  1 
ATOM   5085 C  C   . ARG C 1 71  ? -24.864 2.905   10.462  1   44.57  ? 241 ARG B C   1 
ATOM   5086 O  O   . ARG C 1 71  ? -25.674 3.082   11.371  1   48.24  ? 241 ARG B O   1 
ATOM   5087 C  CB  . ARG C 1 71  ? -24.649 0.619   9.456   1   39.32  ? 241 ARG B CB  1 
ATOM   5088 C  CG  . ARG C 1 71  ? -25.452 -0.515  8.833   1   39.17  ? 241 ARG B CG  1 
ATOM   5089 C  CD  . ARG C 1 71  ? -24.548 -1.633  8.338   1   38.56  ? 241 ARG B CD  1 
ATOM   5090 N  NE  . ARG C 1 71  ? -24.242 -2.537  9.445   1   40.14  ? 241 ARG B NE  1 
ATOM   5091 C  CZ  . ARG C 1 71  ? -23.148 -3.283  9.509   1   40.41  ? 241 ARG B CZ  1 
ATOM   5092 N  NH1 . ARG C 1 71  ? -22.306 -3.334  8.494   1   38.7   ? 241 ARG B NH1 1 
ATOM   5093 N  NH2 . ARG C 1 71  ? -22.897 -3.947  10.61   1   40.38  ? 241 ARG B NH2 1 
ATOM   5094 N  N   . PHE C 1 72  ? -23.694 3.528   10.462  1   42.47  ? 242 PHE B N   1 
ATOM   5095 C  CA  . PHE C 1 72  ? -23.301 4.351   11.635  1   44.21  ? 242 PHE B CA  1 
ATOM   5096 C  C   . PHE C 1 72  ? -24.212 5.571   11.726  1   46.61  ? 242 PHE B C   1 
ATOM   5097 O  O   . PHE C 1 72  ? -24.662 5.917   12.824  1   49.28  ? 242 PHE B O   1 
ATOM   5098 C  CB  . PHE C 1 72  ? -21.835 4.768   11.515  1   41.18  ? 242 PHE B CB  1 
ATOM   5099 C  CG  . PHE C 1 72  ? -21.258 5.627   12.63   1   41.24  ? 242 PHE B CG  1 
ATOM   5100 C  CD1 . PHE C 1 72  ? -20.579 5.049   13.693  1   40.42  ? 242 PHE B CD1 1 
ATOM   5101 C  CD2 . PHE C 1 72  ? -21.363 7.012   12.595  1   44.36  ? 242 PHE B CD2 1 
ATOM   5102 C  CE1 . PHE C 1 72  ? -20.042 5.832   14.699  1   43.79  ? 242 PHE B CE1 1 
ATOM   5103 C  CE2 . PHE C 1 72  ? -20.824 7.789   13.605  1   44.37  ? 242 PHE B CE2 1 
ATOM   5104 C  CZ  . PHE C 1 72  ? -20.166 7.198   14.654  1   44.53  ? 242 PHE B CZ  1 
ATOM   5105 N  N   . LEU C 1 73  ? -24.507 6.194   10.591  1   45.67  ? 243 LEU B N   1 
ATOM   5106 C  CA  . LEU C 1 73  ? -25.305 7.444   10.575  1   47.47  ? 243 LEU B CA  1 
ATOM   5107 C  C   . LEU C 1 73  ? -26.789 7.147   10.812  1   50.13  ? 243 LEU B C   1 
ATOM   5108 O  O   . LEU C 1 73  ? -27.557 8.104   10.976  1   53.76  ? 243 LEU B O   1 
ATOM   5109 C  CB  . LEU C 1 73  ? -25.067 8.121   9.23    1   45.1   ? 243 LEU B CB  1 
ATOM   5110 C  CG  . LEU C 1 73  ? -23.674 8.707   8.998   1   41.99  ? 243 LEU B CG  1 
ATOM   5111 C  CD1 . LEU C 1 73  ? -23.709 9.532   7.733   1   38.63  ? 243 LEU B CD1 1 
ATOM   5112 C  CD2 . LEU C 1 73  ? -23.244 9.55    10.176  1   44.67  ? 243 LEU B CD2 1 
ATOM   5113 N  N   . SER C 1 74  ? -27.165 5.876   10.841  1   49.49  ? 244 SER B N   1 
ATOM   5114 C  CA  . SER C 1 74  ? -28.567 5.485   11.115  1   51.49  ? 244 SER B CA  1 
ATOM   5115 C  C   . SER C 1 74  ? -28.772 5.388   12.631  1   53.33  ? 244 SER B C   1 
ATOM   5116 O  O   . SER C 1 74  ? -29.907 5.142   13.056  1   52.55  ? 244 SER B O   1 
ATOM   5117 C  CB  . SER C 1 74  ? -28.893 4.187   10.432  1   50.27  ? 244 SER B CB  1 
ATOM   5118 O  OG  . SER C 1 74  ? -28.644 4.238   9.037   1   50.67  ? 244 SER B OG  1 
ATOM   5119 N  N   . SER C 1 75  ? -27.707 5.592   13.405  1   52.26  ? 245 SER B N   1 
ATOM   5120 C  CA  . SER C 1 75  ? -27.79  5.456   14.878  1   52.7   ? 245 SER B CA  1 
ATOM   5121 C  C   . SER C 1 75  ? -27.088 6.634   15.554  1   54.79  ? 245 SER B C   1 
ATOM   5122 O  O   . SER C 1 75  ? -27.402 6.899   16.72   1   56.7   ? 245 SER B O   1 
ATOM   5123 C  CB  . SER C 1 75  ? -27.182 4.165   15.318  1   50.54  ? 245 SER B CB  1 
ATOM   5124 O  OG  . SER C 1 75  ? -25.94  3.945   14.668  1   52.75  ? 245 SER B OG  1 
ATOM   5125 N  N   . MET C 1 76  ? -26.191 7.314   14.847  1   51.53  ? 246 MET B N   1 
ATOM   5126 C  CA  . MET C 1 76  ? -25.391 8.382   15.493  1   51.29  ? 246 MET B CA  1 
ATOM   5127 C  C   . MET C 1 76  ? -25.537 9.71    14.747  1   52.07  ? 246 MET B C   1 
ATOM   5128 O  O   . MET C 1 76  ? -25.365 9.724   13.521  1   51.37  ? 246 MET B O   1 
ATOM   5129 C  CB  . MET C 1 76  ? -23.913 7.992   15.534  1   48.91  ? 246 MET B CB  1 
ATOM   5130 C  CG  . MET C 1 76  ? -23.652 6.627   16.12   1   46.19  ? 246 MET B CG  1 
ATOM   5131 S  SD  . MET C 1 76  ? -23.692 6.669   17.92   1   49.91  ? 246 MET B SD  1 
ATOM   5132 C  CE  . MET C 1 76  ? -22.101 7.421   18.277  1   49.91  ? 246 MET B CE  1 
ATOM   5133 N  N   . SER C 1 77  ? -25.843 10.776  15.484  1   54.37  ? 247 SER B N   1 
ATOM   5134 C  CA  . SER C 1 77  ? -25.968 12.124  14.884  1   56.94  ? 247 SER B CA  1 
ATOM   5135 C  C   . SER C 1 77  ? -24.569 12.726  14.753  1   59.22  ? 247 SER B C   1 
ATOM   5136 O  O   . SER C 1 77  ? -23.815 12.644  15.731  1   64.85  ? 247 SER B O   1 
ATOM   5137 C  CB  . SER C 1 77  ? -26.877 12.989  15.697  1   56.19  ? 247 SER B CB  1 
ATOM   5138 O  OG  . SER C 1 77  ? -28.162 12.399  15.818  1   57.19  ? 247 SER B OG  1 
ATOM   5139 N  N   . VAL C 1 78  ? -24.247 13.311  13.599  1   55.25  ? 248 VAL B N   1 
ATOM   5140 C  CA  . VAL C 1 78  ? -22.895 13.797  13.363  1   53.73  ? 248 VAL B CA  1 
ATOM   5141 C  C   . VAL C 1 78  ? -22.927 15.228  12.837  1   55.37  ? 248 VAL B C   1 
ATOM   5142 O  O   . VAL C 1 78  ? -23.659 15.512  11.901  1   58.76  ? 248 VAL B O   1 
ATOM   5143 C  CB  . VAL C 1 78  ? -22.211 12.851  12.369  1   52.06  ? 248 VAL B CB  1 
ATOM   5144 C  CG1 . VAL C 1 78  ? -20.856 13.378  11.95   1   52.56  ? 248 VAL B CG1 1 
ATOM   5145 C  CG2 . VAL C 1 78  ? -22.036 11.459  12.964  1   53.09  ? 248 VAL B CG2 1 
ATOM   5146 N  N   . LEU C 1 79  ? -22.137 16.125  13.451  1   56.48  ? 249 LEU B N   1 
ATOM   5147 C  CA  . LEU C 1 79  ? -21.918 17.466  12.922  1   58.18  ? 249 LEU B CA  1 
ATOM   5148 C  C   . LEU C 1 79  ? -21.201 17.37   11.572  1   58.56  ? 249 LEU B C   1 
ATOM   5149 O  O   . LEU C 1 79  ? -20.427 16.441  11.325  1   54.47  ? 249 LEU B O   1 
ATOM   5150 C  CB  . LEU C 1 79  ? -21.107 18.319  13.899  1   59.23  ? 249 LEU B CB  1 
ATOM   5151 C  CG  . LEU C 1 79  ? -21.768 18.739  15.217  1   60.78  ? 249 LEU B CG  1 
ATOM   5152 C  CD1 . LEU C 1 79  ? -21.013 19.943  15.719  1   61.09  ? 249 LEU B CD1 1 
ATOM   5153 C  CD2 . LEU C 1 79  ? -23.265 19.014  15.119  1   60.84  ? 249 LEU B CD2 1 
ATOM   5154 N  N   . ARG C 1 80  ? -21.455 18.348  10.693  1   58.57  ? 250 ARG B N   1 
ATOM   5155 C  CA  . ARG C 1 80  ? -20.892 18.285  9.354   1   56.45  ? 250 ARG B CA  1 
ATOM   5156 C  C   . ARG C 1 80  ? -19.364 18.325  9.422   1   56.75  ? 250 ARG B C   1 
ATOM   5157 O  O   . ARG C 1 80  ? -18.707 17.695  8.594   1   55.15  ? 250 ARG B O   1 
ATOM   5158 C  CB  . ARG C 1 80  ? -21.503 19.367  8.464   1   57.99  ? 250 ARG B CB  1 
ATOM   5159 C  CG  . ARG C 1 80  ? -21.057 20.744  8.929   1   62.96  ? 250 ARG B CG  1 
ATOM   5160 C  CD  . ARG C 1 80  ? -21.724 21.782  8.069   1   66.55  ? 250 ARG B CD  1 
ATOM   5161 N  NE  . ARG C 1 80  ? -23.118 21.971  8.478   1   69.76  ? 250 ARG B NE  1 
ATOM   5162 C  CZ  . ARG C 1 80  ? -23.904 22.896  7.95    1   73.83  ? 250 ARG B CZ  1 
ATOM   5163 N  NH1 . ARG C 1 80  ? -23.566 23.514  6.831   1   77.73  ? 250 ARG B NH1 1 
ATOM   5164 N  NH2 . ARG C 1 80  ? -25.044 23.182  8.525   1   75.36  ? 250 ARG B NH2 1 
ATOM   5165 N  N   . GLY C 1 81  ? -18.814 19.016  10.439  1   57.85  ? 251 GLY B N   1 
ATOM   5166 C  CA  . GLY C 1 81  ? -17.38  19.096  10.708  1   56.73  ? 251 GLY B CA  1 
ATOM   5167 C  C   . GLY C 1 81  ? -16.694 17.734  10.87   1   56.05  ? 251 GLY B C   1 
ATOM   5168 O  O   . GLY C 1 81  ? -15.476 17.624  10.715  1   54.34  ? 251 GLY B O   1 
ATOM   5169 N  N   . LYS C 1 82  ? -17.497 16.693  11.161  1   55.2   ? 252 LYS B N   1 
ATOM   5170 C  CA  . LYS C 1 82  ? -16.999 15.401  11.593  1   51.34  ? 252 LYS B CA  1 
ATOM   5171 C  C   . LYS C 1 82  ? -17.453 14.293  10.654  1   50.16  ? 252 LYS B C   1 
ATOM   5172 O  O   . LYS C 1 82  ? -17.032 13.145  10.81   1   50.63  ? 252 LYS B O   1 
ATOM   5173 C  CB  . LYS C 1 82  ? -17.513 15.097  12.996  1   51.35  ? 252 LYS B CB  1 
ATOM   5174 C  CG  . LYS C 1 82  ? -16.94  15.995  14.09   1   54.5   ? 252 LYS B CG  1 
ATOM   5175 C  CD  . LYS C 1 82  ? -15.426 15.831  14.177  1   55.15  ? 252 LYS B CD  1 
ATOM   5176 C  CE  . LYS C 1 82  ? -14.835 16.138  15.521  1   54.8   ? 252 LYS B CE  1 
ATOM   5177 N  NZ  . LYS C 1 82  ? -14.923 17.581  15.726  1   55.76  ? 252 LYS B NZ  1 
ATOM   5178 N  N   . LEU C 1 83  ? -18.277 14.632  9.66    1   48.99  ? 253 LEU B N   1 
ATOM   5179 C  CA  . LEU C 1 83  ? -18.752 13.619  8.732   1   48.73  ? 253 LEU B CA  1 
ATOM   5180 C  C   . LEU C 1 83  ? -17.575 12.898  8.065   1   49.79  ? 253 LEU B C   1 
ATOM   5181 O  O   . LEU C 1 83  ? -17.644 11.689  7.856   1   49.52  ? 253 LEU B O   1 
ATOM   5182 C  CB  . LEU C 1 83  ? -19.691 14.247  7.701   1   48.75  ? 253 LEU B CB  1 
ATOM   5183 C  CG  . LEU C 1 83  ? -20.194 13.291  6.614   1   48.43  ? 253 LEU B CG  1 
ATOM   5184 C  CD1 . LEU C 1 83  ? -20.898 12.041  7.161   1   44.49  ? 253 LEU B CD1 1 
ATOM   5185 C  CD2 . LEU C 1 83  ? -21.1   14.059  5.679   1   50.4   ? 253 LEU B CD2 1 
ATOM   5186 N  N   . GLN C 1 84  ? -16.511 13.65   7.732   1   50.36  ? 254 GLN B N   1 
ATOM   5187 C  CA  . GLN C 1 84  ? -15.345 13.141  7.015   1   52.26  ? 254 GLN B CA  1 
ATOM   5188 C  C   . GLN C 1 84  ? -14.491 12.228  7.909   1   50.86  ? 254 GLN B C   1 
ATOM   5189 O  O   . GLN C 1 84  ? -13.876 11.281  7.437   1   48.7   ? 254 GLN B O   1 
ATOM   5190 C  CB  . GLN C 1 84  ? -14.513 14.293  6.44    1   55.14  ? 254 GLN B CB  1 
ATOM   5191 C  CG  . GLN C 1 84  ? -13.477 13.849  5.411   1   55.9   ? 254 GLN B CG  1 
ATOM   5192 C  CD  . GLN C 1 84  ? -12.506 14.916  4.933   1   61.62  ? 254 GLN B CD  1 
ATOM   5193 O  OE1 . GLN C 1 84  ? -11.802 14.687  3.944   1   63.89  ? 254 GLN B OE1 1 
ATOM   5194 N  NE2 . GLN C 1 84  ? -12.444 16.081  5.575   1   59.68  ? 254 GLN B NE2 1 
ATOM   5195 N  N   . LEU C 1 85  ? -14.442 12.518  9.207   1   49.79  ? 255 LEU B N   1 
ATOM   5196 C  CA  . LEU C 1 85  ? -13.724 11.641  10.103  1   49.91  ? 255 LEU B CA  1 
ATOM   5197 C  C   . LEU C 1 85  ? -14.42  10.293  10.16   1   49.05  ? 255 LEU B C   1 
ATOM   5198 O  O   . LEU C 1 85  ? -13.745 9.274   10.251  1   51.17  ? 255 LEU B O   1 
ATOM   5199 C  CB  . LEU C 1 85  ? -13.629 12.292  11.479  1   50     ? 255 LEU B CB  1 
ATOM   5200 C  CG  . LEU C 1 85  ? -12.958 11.477  12.589  1   48.39  ? 255 LEU B CG  1 
ATOM   5201 C  CD1 . LEU C 1 85  ? -11.581 10.968  12.228  1   46.01  ? 255 LEU B CD1 1 
ATOM   5202 C  CD2 . LEU C 1 85  ? -12.889 12.4    13.806  1   50.52  ? 255 LEU B CD2 1 
ATOM   5203 N  N   . VAL C 1 86  ? -15.758 10.304  10.088  1   48.19  ? 256 VAL B N   1 
ATOM   5204 C  CA  . VAL C 1 86  ? -16.532 9.069   10.119  1   46.56  ? 256 VAL B CA  1 
ATOM   5205 C  C   . VAL C 1 86  ? -16.194 8.282   8.865   1   44.46  ? 256 VAL B C   1 
ATOM   5206 O  O   . VAL C 1 86  ? -15.909 7.103   8.933   1   45.85  ? 256 VAL B O   1 
ATOM   5207 C  CB  . VAL C 1 86  ? -18.055 9.288   10.215  1   46.79  ? 256 VAL B CB  1 
ATOM   5208 C  CG1 . VAL C 1 86  ? -18.829 7.983   10.139  1   42.39  ? 256 VAL B CG1 1 
ATOM   5209 C  CG2 . VAL C 1 86  ? -18.44  10.095  11.446  1   45.12  ? 256 VAL B CG2 1 
ATOM   5210 N  N   . GLY C 1 87  ? -16.177 8.966   7.727   1   46.37  ? 257 GLY B N   1 
ATOM   5211 C  CA  . GLY C 1 87  ? -15.9   8.337   6.451   1   44.73  ? 257 GLY B CA  1 
ATOM   5212 C  C   . GLY C 1 87  ? -14.482 7.771   6.383   1   45.8   ? 257 GLY B C   1 
ATOM   5213 O  O   . GLY C 1 87  ? -14.261 6.693   5.831   1   44.87  ? 257 GLY B O   1 
ATOM   5214 N  N   . THR C 1 88  ? -13.509 8.517   6.911   1   47.81  ? 258 THR B N   1 
ATOM   5215 C  CA  . THR C 1 88  ? -12.123 8.069   6.906   1   47.09  ? 258 THR B CA  1 
ATOM   5216 C  C   . THR C 1 88  ? -11.994 6.803   7.744   1   45.58  ? 258 THR B C   1 
ATOM   5217 O  O   . THR C 1 88  ? -11.31  5.879   7.343   1   45.27  ? 258 THR B O   1 
ATOM   5218 C  CB  . THR C 1 88  ? -11.198 9.152   7.446   1   50.14  ? 258 THR B CB  1 
ATOM   5219 O  OG1 . THR C 1 88  ? -11.442 10.296  6.642   1   54.35  ? 258 THR B OG1 1 
ATOM   5220 C  CG2 . THR C 1 88  ? -9.74   8.772   7.313   1   53.08  ? 258 THR B CG2 1 
ATOM   5221 N  N   . ALA C 1 89  ? -12.638 6.756   8.916   1   46.29  ? 259 ALA B N   1 
ATOM   5222 C  CA  . ALA C 1 89  ? -12.509 5.575   9.762   1   47.04  ? 259 ALA B CA  1 
ATOM   5223 C  C   . ALA C 1 89  ? -13.211 4.392   9.107   1   44.7   ? 259 ALA B C   1 
ATOM   5224 O  O   . ALA C 1 89  ? -12.769 3.245   9.243   1   44.45  ? 259 ALA B O   1 
ATOM   5225 C  CB  . ALA C 1 89  ? -13.031 5.828   11.151  1   45.03  ? 259 ALA B CB  1 
ATOM   5226 N  N   . ALA C 1 90  ? -14.308 4.702   8.407   1   40.53  ? 260 ALA B N   1 
ATOM   5227 C  CA  . ALA C 1 90  ? -15.009 3.692   7.65    1   39.85  ? 260 ALA B CA  1 
ATOM   5228 C  C   . ALA C 1 90  ? -14.038 3.063   6.645   1   40.94  ? 260 ALA B C   1 
ATOM   5229 O  O   . ALA C 1 90  ? -13.937 1.841   6.571   1   41.74  ? 260 ALA B O   1 
ATOM   5230 C  CB  . ALA C 1 90  ? -16.234 4.299   7.002   1   37.75  ? 260 ALA B CB  1 
ATOM   5231 N  N   . MET C 1 91  ? -13.317 3.892   5.879   1   40.83  ? 261 MET B N   1 
ATOM   5232 C  CA  . MET C 1 91  ? -12.511 3.422   4.759   1   43.98  ? 261 MET B CA  1 
ATOM   5233 C  C   . MET C 1 91  ? -11.328 2.608   5.305   1   45.55  ? 261 MET B C   1 
ATOM   5234 O  O   . MET C 1 91  ? -10.972 1.558   4.761   1   43.41  ? 261 MET B O   1 
ATOM   5235 C  CB  . MET C 1 91  ? -12.018 4.616   3.923   1   46.15  ? 261 MET B CB  1 
ATOM   5236 C  CG  . MET C 1 91  ? -11.524 4.291   2.527   1   49.97  ? 261 MET B CG  1 
ATOM   5237 S  SD  . MET C 1 91  ? -12.826 3.604   1.482   1   56.18  ? 261 MET B SD  1 
ATOM   5238 C  CE  . MET C 1 91  ? -12.001 3.129   -0.038  1   54.07  ? 261 MET B CE  1 
ATOM   5239 N  N   . LEU C 1 92  ? -10.753 3.099   6.413   1   42.84  ? 262 LEU B N   1 
ATOM   5240 C  CA  . LEU C 1 92  ? -9.696  2.417   7.135   1   43.45  ? 262 LEU B CA  1 
ATOM   5241 C  C   . LEU C 1 92  ? -10.148 1.014   7.547   1   45.03  ? 262 LEU B C   1 
ATOM   5242 O  O   . LEU C 1 92  ? -9.38   0.047   7.456   1   43.84  ? 262 LEU B O   1 
ATOM   5243 C  CB  . LEU C 1 92  ? -9.353  3.255   8.369   1   42.73  ? 262 LEU B CB  1 
ATOM   5244 C  CG  . LEU C 1 92  ? -8.379  2.613   9.371   1   40.67  ? 262 LEU B CG  1 
ATOM   5245 C  CD1 . LEU C 1 92  ? -7.02   2.251   8.734   1   41.88  ? 262 LEU B CD1 1 
ATOM   5246 C  CD2 . LEU C 1 92  ? -8.212  3.519   10.577  1   38.84  ? 262 LEU B CD2 1 
ATOM   5247 N  N   . LEU C 1 93  ? -11.378 0.929   8.073   1   41.97  ? 263 LEU B N   1 
ATOM   5248 C  CA  . LEU C 1 93  ? -11.873 -0.339  8.562   1   42     ? 263 LEU B CA  1 
ATOM   5249 C  C   . LEU C 1 93  ? -12.087 -1.277  7.385   1   43.17  ? 263 LEU B C   1 
ATOM   5250 O  O   . LEU C 1 93  ? -11.659 -2.429  7.438   1   45.15  ? 263 LEU B O   1 
ATOM   5251 C  CB  . LEU C 1 93  ? -13.161 -0.142  9.352   1   43.07  ? 263 LEU B CB  1 
ATOM   5252 C  CG  . LEU C 1 93  ? -12.964 0.268   10.81   1   44.1   ? 263 LEU B CG  1 
ATOM   5253 C  CD1 . LEU C 1 93  ? -14.317 0.615   11.407  1   42.4   ? 263 LEU B CD1 1 
ATOM   5254 C  CD2 . LEU C 1 93  ? -12.322 -0.895  11.586  1   43.4   ? 263 LEU B CD2 1 
ATOM   5255 N  N   . ALA C 1 94  ? -12.784 -0.784  6.348   1   40.74  ? 264 ALA B N   1 
ATOM   5256 C  CA  . ALA C 1 94  ? -13.02  -1.596  5.169   1   38.43  ? 264 ALA B CA  1 
ATOM   5257 C  C   . ALA C 1 94  ? -11.684 -2.125  4.625   1   39.38  ? 264 ALA B C   1 
ATOM   5258 O  O   . ALA C 1 94  ? -11.542 -3.311  4.358   1   37.97  ? 264 ALA B O   1 
ATOM   5259 C  CB  . ALA C 1 94  ? -13.792 -0.795  4.153   1   36.74  ? 264 ALA B CB  1 
ATOM   5260 N  N   . SER C 1 95  ? -10.693 -1.23   4.483   1   42.1   ? 265 SER B N   1 
ATOM   5261 C  CA  . SER C 1 95  ? -9.346  -1.557  4.032   1   41.66  ? 265 SER B CA  1 
ATOM   5262 C  C   . SER C 1 95  ? -8.756  -2.693  4.863   1   41.31  ? 265 SER B C   1 
ATOM   5263 O  O   . SER C 1 95  ? -8.346  -3.684  4.309   1   45.87  ? 265 SER B O   1 
ATOM   5264 C  CB  . SER C 1 95  ? -8.448  -0.36   4.06    1   42.85  ? 265 SER B CB  1 
ATOM   5265 O  OG  . SER C 1 95  ? -8.916  0.649   3.177   1   46.65  ? 265 SER B OG  1 
ATOM   5266 N  N   . LYS C 1 96  ? -8.746  -2.594  6.191   1   41.68  ? 266 LYS B N   1 
ATOM   5267 C  CA  . LYS C 1 96  ? -8.185  -3.674  6.981   1   41.61  ? 266 LYS B CA  1 
ATOM   5268 C  C   . LYS C 1 96  ? -8.958  -4.973  6.743   1   42.35  ? 266 LYS B C   1 
ATOM   5269 O  O   . LYS C 1 96  ? -8.37   -6.055  6.742   1   46.22  ? 266 LYS B O   1 
ATOM   5270 C  CB  . LYS C 1 96  ? -8.237  -3.307  8.463   1   43.93  ? 266 LYS B CB  1 
ATOM   5271 C  CG  . LYS C 1 96  ? -7.258  -2.233  8.899   1   43.74  ? 266 LYS B CG  1 
ATOM   5272 C  CD  . LYS C 1 96  ? -7.382  -1.9    10.38   1   42.15  ? 266 LYS B CD  1 
ATOM   5273 C  CE  . LYS C 1 96  ? -6.455  -0.823  10.839  1   43.58  ? 266 LYS B CE  1 
ATOM   5274 N  NZ  . LYS C 1 96  ? -6.584  -0.513  12.267  1   44.82  ? 266 LYS B NZ  1 
ATOM   5275 N  N   . PHE C 1 97  ? -10.27  -4.877  6.511   1   38.26  ? 267 PHE B N   1 
ATOM   5276 C  CA  . PHE C 1 97  ? -11.065 -6.071  6.34    1   35.77  ? 267 PHE B CA  1 
ATOM   5277 C  C   . PHE C 1 97  ? -10.72  -6.776  5.033   1   37.05  ? 267 PHE B C   1 
ATOM   5278 O  O   . PHE C 1 97  ? -10.544 -8.008  5.005   1   35.54  ? 267 PHE B O   1 
ATOM   5279 C  CB  . PHE C 1 97  ? -12.546 -5.713  6.312   1   36.31  ? 267 PHE B CB  1 
ATOM   5280 C  CG  . PHE C 1 97  ? -13.451 -6.941  6.289   1   38.32  ? 267 PHE B CG  1 
ATOM   5281 C  CD1 . PHE C 1 97  ? -13.74  -7.638  7.458   1   37.66  ? 267 PHE B CD1 1 
ATOM   5282 C  CD2 . PHE C 1 97  ? -14.003 -7.41   5.098   1   37.29  ? 267 PHE B CD2 1 
ATOM   5283 C  CE1 . PHE C 1 97  ? -14.579 -8.754  7.43    1   39.51  ? 267 PHE B CE1 1 
ATOM   5284 C  CE2 . PHE C 1 97  ? -14.824 -8.54   5.076   1   37.2   ? 267 PHE B CE2 1 
ATOM   5285 C  CZ  . PHE C 1 97  ? -15.113 -9.215  6.243   1   36.79  ? 267 PHE B CZ  1 
ATOM   5286 N  N   . GLU C 1 98  ? -10.629 -5.975  3.965   1   35.67  ? 268 GLU B N   1 
ATOM   5287 C  CA  . GLU C 1 98  ? -10.798 -6.491  2.62    1   35.67  ? 268 GLU B CA  1 
ATOM   5288 C  C   . GLU C 1 98  ? -9.483  -6.541  1.844   1   39.02  ? 268 GLU B C   1 
ATOM   5289 O  O   . GLU C 1 98  ? -9.336  -7.413  0.981   1   41.71  ? 268 GLU B O   1 
ATOM   5290 C  CB  . GLU C 1 98  ? -11.816 -5.67   1.829   1   33.75  ? 268 GLU B CB  1 
ATOM   5291 C  CG  . GLU C 1 98  ? -12.28  -6.343  0.541   1   35.5   ? 268 GLU B CG  1 
ATOM   5292 C  CD  . GLU C 1 98  ? -12.913 -7.72   0.767   1   41.21  ? 268 GLU B CD  1 
ATOM   5293 O  OE1 . GLU C 1 98  ? -13.611 -7.886  1.783   1   42.08  ? 268 GLU B OE1 1 
ATOM   5294 O  OE2 . GLU C 1 98  ? -12.749 -8.644  -0.055  1   43.24  ? 268 GLU B OE2 1 
ATOM   5295 N  N   . GLU C 1 99  ? -8.549  -5.623  2.134   1   36.49  ? 269 GLU B N   1 
ATOM   5296 C  CA  . GLU C 1 99  ? -7.351  -5.466  1.33    1   37.49  ? 269 GLU B CA  1 
ATOM   5297 C  C   . GLU C 1 99  ? -6.205  -6.315  1.869   1   41.89  ? 269 GLU B C   1 
ATOM   5298 O  O   . GLU C 1 99  ? -6.033  -6.446  3.08    1   43.04  ? 269 GLU B O   1 
ATOM   5299 C  CB  . GLU C 1 99  ? -6.831  -4.029  1.379   1   39.56  ? 269 GLU B CB  1 
ATOM   5300 C  CG  . GLU C 1 99  ? -7.794  -2.999  0.798   1   41.53  ? 269 GLU B CG  1 
ATOM   5301 C  CD  . GLU C 1 99  ? -7.932  -2.929  -0.713  1   44.32  ? 269 GLU B CD  1 
ATOM   5302 O  OE1 . GLU C 1 99  ? -6.96   -3.307  -1.399  1   47.57  ? 269 GLU B OE1 1 
ATOM   5303 O  OE2 . GLU C 1 99  ? -9.028  -2.548  -1.198  1   44.89  ? 269 GLU B OE2 1 
ATOM   5304 N  N   . ILE C 1 100 ? -5.394  -6.84   0.926   1   43.35  ? 270 ILE B N   1 
ATOM   5305 C  CA  . ILE C 1 100 ? -4.184  -7.581  1.214   1   41.23  ? 270 ILE B CA  1 
ATOM   5306 C  C   . ILE C 1 100 ? -3.237  -6.587  1.859   1   42.93  ? 270 ILE B C   1 
ATOM   5307 O  O   . ILE C 1 100 ? -2.589  -6.926  2.84    1   44.48  ? 270 ILE B O   1 
ATOM   5308 C  CB  . ILE C 1 100 ? -3.591  -8.184  -0.084  1   42.67  ? 270 ILE B CB  1 
ATOM   5309 C  CG1 . ILE C 1 100 ? -4.579  -9.131  -0.789  1   38.96  ? 270 ILE B CG1 1 
ATOM   5310 C  CG2 . ILE C 1 100 ? -2.218  -8.849  0.112   1   38.69  ? 270 ILE B CG2 1 
ATOM   5311 C  CD1 . ILE C 1 100 ? -4.064  -9.677  -2.113  1   38.66  ? 270 ILE B CD1 1 
ATOM   5312 N  N   . TYR C 1 101 ? -3.174  -5.375  1.288   1   45.2   ? 271 TYR B N   1 
ATOM   5313 C  CA  . TYR C 1 101 ? -2.239  -4.333  1.702   1   49.79  ? 271 TYR B CA  1 
ATOM   5314 C  C   . TYR C 1 101 ? -3.018  -3.065  2.02    1   52.42  ? 271 TYR B C   1 
ATOM   5315 O  O   . TYR C 1 101 ? -3.107  -2.165  1.185   1   57.06  ? 271 TYR B O   1 
ATOM   5316 C  CB  . TYR C 1 101 ? -1.225  -4.035  0.592   1   48.84  ? 271 TYR B CB  1 
ATOM   5317 C  CG  . TYR C 1 101 ? -0.291  -5.209  0.378   1   51.49  ? 271 TYR B CG  1 
ATOM   5318 C  CD1 . TYR C 1 101 ? 0.477   -5.69   1.437   1   52.83  ? 271 TYR B CD1 1 
ATOM   5319 C  CD2 . TYR C 1 101 ? -0.222  -5.876  -0.85   1   52.52  ? 271 TYR B CD2 1 
ATOM   5320 C  CE1 . TYR C 1 101 ? 1.306   -6.791  1.28    1   55.33  ? 271 TYR B CE1 1 
ATOM   5321 C  CE2 . TYR C 1 101 ? 0.625   -6.965  -1.023  1   52.96  ? 271 TYR B CE2 1 
ATOM   5322 C  CZ  . TYR C 1 101 ? 1.367   -7.433  0.055   1   56.85  ? 271 TYR B CZ  1 
ATOM   5323 O  OH  . TYR C 1 101 ? 2.196   -8.51   -0.038  1   69.6   ? 271 TYR B OH  1 
ATOM   5324 N  N   . PRO C 1 102 ? -3.647  -2.965  3.212   1   51.3   ? 272 PRO B N   1 
ATOM   5325 C  CA  . PRO C 1 102 ? -4.37   -1.745  3.57    1   48.31  ? 272 PRO B CA  1 
ATOM   5326 C  C   . PRO C 1 102 ? -3.329  -0.637  3.617   1   49.43  ? 272 PRO B C   1 
ATOM   5327 O  O   . PRO C 1 102 ? -2.175  -0.861  3.982   1   51.08  ? 272 PRO B O   1 
ATOM   5328 C  CB  . PRO C 1 102 ? -4.967  -2.025  4.936   1   47.21  ? 272 PRO B CB  1 
ATOM   5329 C  CG  . PRO C 1 102 ? -4.169  -3.197  5.447   1   49.62  ? 272 PRO B CG  1 
ATOM   5330 C  CD  . PRO C 1 102 ? -3.662  -3.988  4.263   1   48.37  ? 272 PRO B CD  1 
ATOM   5331 N  N   . PRO C 1 103 ? -3.698  0.592   3.213   1   52.23  ? 273 PRO B N   1 
ATOM   5332 C  CA  . PRO C 1 103 ? -2.85   1.769   3.463   1   53.72  ? 273 PRO B CA  1 
ATOM   5333 C  C   . PRO C 1 103 ? -2.704  2.003   4.963   1   54.51  ? 273 PRO B C   1 
ATOM   5334 O  O   . PRO C 1 103 ? -3.577  1.654   5.757   1   53.84  ? 273 PRO B O   1 
ATOM   5335 C  CB  . PRO C 1 103 ? -3.564  2.95    2.788   1   51.93  ? 273 PRO B CB  1 
ATOM   5336 C  CG  . PRO C 1 103 ? -4.72   2.325   2.008   1   51.33  ? 273 PRO B CG  1 
ATOM   5337 C  CD  . PRO C 1 103 ? -4.945  0.899   2.491   1   49.48  ? 273 PRO B CD  1 
ATOM   5338 N  N   . GLU C 1 104 ? -1.598  2.624   5.35    1   56.85  ? 274 GLU B N   1 
ATOM   5339 C  CA  . GLU C 1 104 ? -1.354  2.871   6.756   1   60.12  ? 274 GLU B CA  1 
ATOM   5340 C  C   . GLU C 1 104 ? -2.281  3.962   7.277   1   58.89  ? 274 GLU B C   1 
ATOM   5341 O  O   . GLU C 1 104 ? -2.885  4.703   6.508   1   58.91  ? 274 GLU B O   1 
ATOM   5342 C  CB  . GLU C 1 104 ? 0.112   3.255   6.914   1   71.45  ? 274 GLU B CB  1 
ATOM   5343 C  CG  . GLU C 1 104 ? 1.041   2.053   6.75    1   79.07  ? 274 GLU B CG  1 
ATOM   5344 C  CD  . GLU C 1 104 ? 2.5     2.452   6.722   1   89.13  ? 274 GLU B CD  1 
ATOM   5345 O  OE1 . GLU C 1 104 ? 3.352   1.535   6.771   1   98.74  ? 274 GLU B OE1 1 
ATOM   5346 O  OE2 . GLU C 1 104 ? 2.767   3.678   6.642   1   91.71  ? 274 GLU B OE2 1 
ATOM   5347 N  N   . VAL C 1 105 ? -2.398  4.043   8.603   1   57.87  ? 275 VAL B N   1 
ATOM   5348 C  CA  . VAL C 1 105 ? -3.252  5.042   9.224   1   57.55  ? 275 VAL B CA  1 
ATOM   5349 C  C   . VAL C 1 105 ? -2.762  6.444   8.859   1   63.38  ? 275 VAL B C   1 
ATOM   5350 O  O   . VAL C 1 105 ? -3.573  7.336   8.622   1   65.13  ? 275 VAL B O   1 
ATOM   5351 C  CB  . VAL C 1 105 ? -3.278  4.839   10.744  1   54.25  ? 275 VAL B CB  1 
ATOM   5352 C  CG1 . VAL C 1 105 ? -4.005  5.973   11.448  1   55.28  ? 275 VAL B CG1 1 
ATOM   5353 C  CG2 . VAL C 1 105 ? -3.895  3.498   11.093  1   54.85  ? 275 VAL B CG2 1 
ATOM   5354 N  N   . ALA C 1 106 ? -1.434  6.641   8.84    1   64.25  ? 276 ALA B N   1 
ATOM   5355 C  CA  . ALA C 1 106 ? -0.884  7.943   8.509   1   64.73  ? 276 ALA B CA  1 
ATOM   5356 C  C   . ALA C 1 106 ? -1.386  8.38    7.132   1   61.73  ? 276 ALA B C   1 
ATOM   5357 O  O   . ALA C 1 106 ? -1.667  9.552   6.896   1   62.94  ? 276 ALA B O   1 
ATOM   5358 C  CB  . ALA C 1 106 ? 0.626   7.931   8.616   1   64.27  ? 276 ALA B CB  1 
ATOM   5359 N  N   . GLU C 1 107 ? -1.534  7.418   6.23    1   60.17  ? 277 GLU B N   1 
ATOM   5360 C  CA  . GLU C 1 107 ? -2.055  7.721   4.91    1   64.57  ? 277 GLU B CA  1 
ATOM   5361 C  C   . GLU C 1 107 ? -3.492  8.228   5.01    1   60.49  ? 277 GLU B C   1 
ATOM   5362 O  O   . GLU C 1 107 ? -3.826  9.255   4.415   1   56.95  ? 277 GLU B O   1 
ATOM   5363 C  CB  . GLU C 1 107 ? -1.796  6.548   3.967   1   69.25  ? 277 GLU B CB  1 
ATOM   5364 C  CG  . GLU C 1 107 ? -0.386  6.636   3.386   1   81.13  ? 277 GLU B CG  1 
ATOM   5365 C  CD  . GLU C 1 107 ? 0.337   5.382   2.943   1   88.15  ? 277 GLU B CD  1 
ATOM   5366 O  OE1 . GLU C 1 107 ? 1.44    5.615   2.39    1   92.97  ? 277 GLU B OE1 1 
ATOM   5367 O  OE2 . GLU C 1 107 ? -0.15   4.23    3.161   1   84.63  ? 277 GLU B OE2 1 
ATOM   5368 N  N   . PHE C 1 108 ? -4.319  7.527   5.795   1   56.96  ? 278 PHE B N   1 
ATOM   5369 C  CA  . PHE C 1 108 ? -5.691  7.968   6.004   1   54.76  ? 278 PHE B CA  1 
ATOM   5370 C  C   . PHE C 1 108 ? -5.734  9.397   6.57    1   59.57  ? 278 PHE B C   1 
ATOM   5371 O  O   . PHE C 1 108 ? -6.619  10.148  6.194   1   64.77  ? 278 PHE B O   1 
ATOM   5372 C  CB  . PHE C 1 108 ? -6.514  6.92    6.748   1   49.43  ? 278 PHE B CB  1 
ATOM   5373 C  CG  . PHE C 1 108 ? -6.891  5.76    5.848   1   49.31  ? 278 PHE B CG  1 
ATOM   5374 C  CD1 . PHE C 1 108 ? -7.95   5.878   4.957   1   50.27  ? 278 PHE B CD1 1 
ATOM   5375 C  CD2 . PHE C 1 108 ? -6.183  4.552   5.876   1   50.89  ? 278 PHE B CD2 1 
ATOM   5376 C  CE1 . PHE C 1 108 ? -8.279  4.826   4.11    1   50.4   ? 278 PHE B CE1 1 
ATOM   5377 C  CE2 . PHE C 1 108 ? -6.52   3.491   5.036   1   48.32  ? 278 PHE B CE2 1 
ATOM   5378 C  CZ  . PHE C 1 108 ? -7.575  3.629   4.161   1   49.88  ? 278 PHE B CZ  1 
ATOM   5379 N  N   . VAL C 1 109 ? -4.768  9.802   7.413   1   56.5   ? 279 VAL B N   1 
ATOM   5380 C  CA  . VAL C 1 109 ? -4.767  11.132  7.993   1   57.25  ? 279 VAL B CA  1 
ATOM   5381 C  C   . VAL C 1 109 ? -4.341  12.143  6.933   1   63.03  ? 279 VAL B C   1 
ATOM   5382 O  O   . VAL C 1 109 ? -4.788  13.288  6.941   1   67.91  ? 279 VAL B O   1 
ATOM   5383 C  CB  . VAL C 1 109 ? -3.77   11.2    9.166   1   59.51  ? 279 VAL B CB  1 
ATOM   5384 C  CG1 . VAL C 1 109 ? -3.588  12.615  9.723   1   56.61  ? 279 VAL B CG1 1 
ATOM   5385 C  CG2 . VAL C 1 109 ? -4.068  10.181  10.265  1   58.8   ? 279 VAL B CG2 1 
ATOM   5386 N  N   . TYR C 1 110 ? -3.425  11.741  6.062   1   65.78  ? 280 TYR B N   1 
ATOM   5387 C  CA  . TYR C 1 110 ? -2.89   12.679  5.045   1   69.7   ? 280 TYR B CA  1 
ATOM   5388 C  C   . TYR C 1 110 ? -3.982  13.065  4.061   1   72.47  ? 280 TYR B C   1 
ATOM   5389 O  O   . TYR C 1 110 ? -4      14.221  3.601   1   76.81  ? 280 TYR B O   1 
ATOM   5390 C  CB  . TYR C 1 110 ? -1.711  11.985  4.365   1   72.48  ? 280 TYR B CB  1 
ATOM   5391 C  CG  . TYR C 1 110 ? -1.106  12.72   3.179   1   81.68  ? 280 TYR B CG  1 
ATOM   5392 C  CD1 . TYR C 1 110 ? -0.14   13.699  3.364   1   87     ? 280 TYR B CD1 1 
ATOM   5393 C  CD2 . TYR C 1 110 ? -1.489  12.423  1.878   1   84.11  ? 280 TYR B CD2 1 
ATOM   5394 C  CE1 . TYR C 1 110 ? 0.42    14.369  2.291   1   92.27  ? 280 TYR B CE1 1 
ATOM   5395 C  CE2 . TYR C 1 110 ? -0.938  13.087  0.796   1   92.69  ? 280 TYR B CE2 1 
ATOM   5396 C  CZ  . TYR C 1 110 ? 0.02    14.063  1.003   1   97.69  ? 280 TYR B CZ  1 
ATOM   5397 O  OH  . TYR C 1 110 ? 0.572   14.723  -0.055  1   98.64  ? 280 TYR B OH  1 
ATOM   5398 N  N   . ILE C 1 111 ? -4.874  12.131  3.736   1   69.07  ? 281 ILE B N   1 
ATOM   5399 C  CA  . ILE C 1 111 ? -5.915  12.419  2.707   1   68.2   ? 281 ILE B CA  1 
ATOM   5400 C  C   . ILE C 1 111 ? -6.992  13.322  3.325   1   69.47  ? 281 ILE B C   1 
ATOM   5401 O  O   . ILE C 1 111 ? -7.828  13.831  2.565   1   65.84  ? 281 ILE B O   1 
ATOM   5402 C  CB  . ILE C 1 111 ? -6.478  11.121  2.1     1   64.73  ? 281 ILE B CB  1 
ATOM   5403 C  CG1 . ILE C 1 111 ? -7.143  10.242  3.137   1   63.86  ? 281 ILE B CG1 1 
ATOM   5404 C  CG2 . ILE C 1 111 ? -5.381  10.369  1.352   1   65.11  ? 281 ILE B CG2 1 
ATOM   5405 C  CD1 . ILE C 1 111 ? -7.898  9.061   2.558   1   68.95  ? 281 ILE B CD1 1 
ATOM   5406 N  N   . THR C 1 112 ? -6.955  13.522  4.642   1   69.71  ? 282 THR B N   1 
ATOM   5407 C  CA  . THR C 1 112 ? -7.897  14.449  5.297   1   71.05  ? 282 THR B CA  1 
ATOM   5408 C  C   . THR C 1 112 ? -7.29   15.836  5.315   1   78.26  ? 282 THR B C   1 
ATOM   5409 O  O   . THR C 1 112 ? -7.889  16.721  5.934   1   77.98  ? 282 THR B O   1 
ATOM   5410 C  CB  . THR C 1 112 ? -8.216  13.971  6.71    1   66.8   ? 282 THR B CB  1 
ATOM   5411 O  OG1 . THR C 1 112 ? -7.026  14.183  7.461   1   67.02  ? 282 THR B OG1 1 
ATOM   5412 C  CG2 . THR C 1 112 ? -8.643  12.517  6.749   1   59.91  ? 282 THR B CG2 1 
ATOM   5413 N  N   . ASP C 1 113 ? -6.142  16.024  4.662   1   83.46  ? 283 ASP B N   1 
ATOM   5414 C  CA  . ASP C 1 113 ? -5.456  17.346  4.626   1   94.64  ? 283 ASP B CA  1 
ATOM   5415 C  C   . ASP C 1 113 ? -5.26   17.837  6.061   1   96.71  ? 283 ASP B C   1 
ATOM   5416 O  O   . ASP C 1 113 ? -5.537  19.021  6.331   1   85.95  ? 283 ASP B O   1 
ATOM   5417 C  CB  . ASP C 1 113 ? -6.168  18.323  3.706   1   101.04 ? 283 ASP B CB  1 
ATOM   5418 C  CG  . ASP C 1 113 ? -5.273  19.353  3.033   1   110.12 ? 283 ASP B CG  1 
ATOM   5419 O  OD1 . ASP C 1 113 ? -4.053  19.331  3.298   1   107.71 ? 283 ASP B OD1 1 
ATOM   5420 O  OD2 . ASP C 1 113 ? -5.805  20.169  2.255   1   113.26 ? 283 ASP B OD2 1 
ATOM   5421 N  N   . ASP C 1 114 ? -4.82   16.946  6.946   1   104.38 ? 284 ASP B N   1 
ATOM   5422 C  CA  . ASP C 1 114 ? -4.545  17.309  8.364   1   108.98 ? 284 ASP B CA  1 
ATOM   5423 C  C   . ASP C 1 114 ? -5.761  17.992  8.996   1   100.91 ? 284 ASP B C   1 
ATOM   5424 O  O   . ASP C 1 114 ? -5.564  18.756  9.959   1   94.22  ? 284 ASP B O   1 
ATOM   5425 C  CB  . ASP C 1 114 ? -3.242  18.083  8.471   1   124.89 ? 284 ASP B CB  1 
ATOM   5426 C  CG  . ASP C 1 114 ? -2.063  17.453  7.745   1   127.75 ? 284 ASP B CG  1 
ATOM   5427 O  OD1 . ASP C 1 114 ? -2.173  16.265  7.375   1   130.85 ? 284 ASP B OD1 1 
ATOM   5428 O  OD2 . ASP C 1 114 ? -1.049  18.154  7.551   1   117.73 ? 284 ASP B OD2 1 
ATOM   5429 N  N   . THR C 1 115 ? -6.967  17.709  8.501   1   93.99  ? 285 THR B N   1 
ATOM   5430 C  CA  . THR C 1 115 ? -8.179  18.236  9.153   1   87.42  ? 285 THR B CA  1 
ATOM   5431 C  C   . THR C 1 115 ? -8.31   17.514  10.47   1   81.58  ? 285 THR B C   1 
ATOM   5432 O  O   . THR C 1 115 ? -8.781  18.126  11.444  1   84.51  ? 285 THR B O   1 
ATOM   5433 C  CB  . THR C 1 115 ? -9.393  18.005  8.256   1   84.81  ? 285 THR B CB  1 
ATOM   5434 O  OG1 . THR C 1 115 ? -9.093  18.699  7.051   1   82.84  ? 285 THR B OG1 1 
ATOM   5435 C  CG2 . THR C 1 115 ? -10.684 18.529  8.855   1   81.79  ? 285 THR B CG2 1 
ATOM   5436 N  N   . TYR C 1 116 ? -7.873  16.258  10.508  1   71.79  ? 286 TYR B N   1 
ATOM   5437 C  CA  . TYR C 1 116 ? -8.003  15.442  11.738  1   67.49  ? 286 TYR B CA  1 
ATOM   5438 C  C   . TYR C 1 116 ? -6.657  14.869  12.13   1   67.21  ? 286 TYR B C   1 
ATOM   5439 O  O   . TYR C 1 116 ? -5.785  14.723  11.262  1   69     ? 286 TYR B O   1 
ATOM   5440 C  CB  . TYR C 1 116 ? -9.025  14.323  11.526  1   61.38  ? 286 TYR B CB  1 
ATOM   5441 C  CG  . TYR C 1 116 ? -10.381 14.736  10.974  1   60.85  ? 286 TYR B CG  1 
ATOM   5442 C  CD1 . TYR C 1 116 ? -11.313 15.384  11.771  1   60.64  ? 286 TYR B CD1 1 
ATOM   5443 C  CD2 . TYR C 1 116 ? -10.732 14.453  9.661   1   58.05  ? 286 TYR B CD2 1 
ATOM   5444 C  CE1 . TYR C 1 116 ? -12.551 15.752  11.274  1   57.53  ? 286 TYR B CE1 1 
ATOM   5445 C  CE2 . TYR C 1 116 ? -11.965 14.817  9.152   1   56.24  ? 286 TYR B CE2 1 
ATOM   5446 C  CZ  . TYR C 1 116 ? -12.877 15.465  9.962   1   56.23  ? 286 TYR B CZ  1 
ATOM   5447 O  OH  . TYR C 1 116 ? -14.094 15.821  9.466   1   57.73  ? 286 TYR B OH  1 
ATOM   5448 N  N   . THR C 1 117 ? -6.485  14.582  13.415  1   63.25  ? 287 THR B N   1 
ATOM   5449 C  CA  . THR C 1 117 ? -5.273  13.988  13.947  1   61.97  ? 287 THR B CA  1 
ATOM   5450 C  C   . THR C 1 117 ? -5.384  12.472  13.835  1   60.62  ? 287 THR B C   1 
ATOM   5451 O  O   . THR C 1 117 ? -6.469  11.937  13.581  1   57.41  ? 287 THR B O   1 
ATOM   5452 C  CB  . THR C 1 117 ? -5.057  14.366  15.415  1   61.5   ? 287 THR B CB  1 
ATOM   5453 O  OG1 . THR C 1 117 ? -6.039  13.684  16.195  1   60.58  ? 287 THR B OG1 1 
ATOM   5454 C  CG2 . THR C 1 117 ? -5.043  15.857  15.668  1   61.18  ? 287 THR B CG2 1 
ATOM   5455 N  N   . LYS C 1 118 ? -4.242  11.809  14.085  1   63.18  ? 288 LYS B N   1 
ATOM   5456 C  CA  . LYS C 1 118 ? -4.135  10.363  14.048  1   63.28  ? 288 LYS B CA  1 
ATOM   5457 C  C   . LYS C 1 118 ? -4.923  9.773   15.218  1   62.39  ? 288 LYS B C   1 
ATOM   5458 O  O   . LYS C 1 118 ? -5.57   8.731   15.06   1   59.05  ? 288 LYS B O   1 
ATOM   5459 C  CB  . LYS C 1 118 ? -2.664  9.947   14.016  1   65.6   ? 288 LYS B CB  1 
ATOM   5460 C  CG  . LYS C 1 118 ? -2.452  8.452   13.807  1   68.6   ? 288 LYS B CG  1 
ATOM   5461 C  CD  . LYS C 1 118 ? -1.037  7.959   14.094  1   72.97  ? 288 LYS B CD  1 
ATOM   5462 C  CE  . LYS C 1 118 ? -1.044  6.46    14.037  1   81.43  ? 288 LYS B CE  1 
ATOM   5463 N  NZ  . LYS C 1 118 ? 0.17    5.825   14.534  1   89.91  ? 288 LYS B NZ  1 
ATOM   5464 N  N   . LYS C 1 119 ? -4.898  10.486  16.356  1   64.56  ? 289 LYS B N   1 
ATOM   5465 C  CA  . LYS C 1 119 ? -5.65   10.126  17.551  1   65.31  ? 289 LYS B CA  1 
ATOM   5466 C  C   . LYS C 1 119 ? -7.143  10.111  17.234  1   62.72  ? 289 LYS B C   1 
ATOM   5467 O  O   . LYS C 1 119 ? -7.835  9.146   17.546  1   61.02  ? 289 LYS B O   1 
ATOM   5468 C  CB  . LYS C 1 119 ? -5.308  11.111  18.671  1   71.26  ? 289 LYS B CB  1 
ATOM   5469 C  CG  . LYS C 1 119 ? -3.897  11.072  19.214  1   81.09  ? 289 LYS B CG  1 
ATOM   5470 C  CD  . LYS C 1 119 ? -3.657  12.114  20.312  1   96.43  ? 289 LYS B CD  1 
ATOM   5471 C  CE  . LYS C 1 119 ? -2.274  12.133  20.934  1   105.74 ? 289 LYS B CE  1 
ATOM   5472 N  NZ  . LYS C 1 119 ? -2.083  13.159  21.961  1   109.28 ? 289 LYS B NZ  1 
ATOM   5473 N  N   . GLN C 1 120 ? -7.623  11.163  16.56   1   60.92  ? 290 GLN B N   1 
ATOM   5474 C  CA  . GLN C 1 120 ? -9.027  11.26   16.182  1   58.35  ? 290 GLN B CA  1 
ATOM   5475 C  C   . GLN C 1 120 ? -9.45   10.067  15.313  1   56.98  ? 290 GLN B C   1 
ATOM   5476 O  O   . GLN C 1 120 ? -10.504 9.458   15.524  1   53.12  ? 290 GLN B O   1 
ATOM   5477 C  CB  . GLN C 1 120 ? -9.303  12.604  15.51   1   55.93  ? 290 GLN B CB  1 
ATOM   5478 C  CG  . GLN C 1 120 ? -9.379  13.769  16.487  1   58.99  ? 290 GLN B CG  1 
ATOM   5479 C  CD  . GLN C 1 120 ? -9.805  15.061  15.824  1   61.56  ? 290 GLN B CD  1 
ATOM   5480 O  OE1 . GLN C 1 120 ? -9.171  15.529  14.875  1   63.27  ? 290 GLN B OE1 1 
ATOM   5481 N  NE2 . GLN C 1 120 ? -10.909 15.636  16.289  1   60.49  ? 290 GLN B NE2 1 
ATOM   5482 N  N   . VAL C 1 121 ? -8.642  9.76    14.296  1   56.24  ? 291 VAL B N   1 
ATOM   5483 C  CA  . VAL C 1 121 ? -8.99   8.688   13.389  1   55.19  ? 291 VAL B CA  1 
ATOM   5484 C  C   . VAL C 1 121 ? -9.086  7.367   14.152  1   56.84  ? 291 VAL B C   1 
ATOM   5485 O  O   . VAL C 1 121 ? -10.041 6.603   13.977  1   56.51  ? 291 VAL B O   1 
ATOM   5486 C  CB  . VAL C 1 121 ? -7.992  8.579   12.226  1   54.83  ? 291 VAL B CB  1 
ATOM   5487 C  CG1 . VAL C 1 121 ? -8.289  7.351   11.369  1   52.94  ? 291 VAL B CG1 1 
ATOM   5488 C  CG2 . VAL C 1 121 ? -8.015  9.828   11.37   1   55.4   ? 291 VAL B CG2 1 
ATOM   5489 N  N   . LEU C 1 122 ? -8.062  7.069   14.955  1   55.89  ? 292 LEU B N   1 
ATOM   5490 C  CA  . LEU C 1 122 ? -8.05   5.806   15.67   1   55.17  ? 292 LEU B CA  1 
ATOM   5491 C  C   . LEU C 1 122 ? -9.247  5.701   16.61   1   55.34  ? 292 LEU B C   1 
ATOM   5492 O  O   . LEU C 1 122 ? -9.817  4.623   16.74   1   56.93  ? 292 LEU B O   1 
ATOM   5493 C  CB  . LEU C 1 122 ? -6.741  5.698   16.446  1   55.91  ? 292 LEU B CB  1 
ATOM   5494 C  CG  . LEU C 1 122 ? -5.505  5.415   15.594  1   56.21  ? 292 LEU B CG  1 
ATOM   5495 C  CD1 . LEU C 1 122 ? -4.318  5.083   16.512  1   56.4   ? 292 LEU B CD1 1 
ATOM   5496 C  CD2 . LEU C 1 122 ? -5.832  4.327   14.541  1   53.29  ? 292 LEU B CD2 1 
ATOM   5497 N  N   . ARG C 1 123 ? -9.573  6.81    17.296  1   56.74  ? 293 ARG B N   1 
ATOM   5498 C  CA  . ARG C 1 123 ? -10.669 6.879   18.25   1   56.15  ? 293 ARG B CA  1 
ATOM   5499 C  C   . ARG C 1 123 ? -12.003 6.681   17.527  1   53.69  ? 293 ARG B C   1 
ATOM   5500 O  O   . ARG C 1 123 ? -12.863 5.972   18.033  1   56.22  ? 293 ARG B O   1 
ATOM   5501 C  CB  . ARG C 1 123 ? -10.633 8.176   19.06   1   59.46  ? 293 ARG B CB  1 
ATOM   5502 C  CG  . ARG C 1 123 ? -9.619  8.157   20.192  1   66.3   ? 293 ARG B CG  1 
ATOM   5503 C  CD  . ARG C 1 123 ? -9.767  9.296   21.186  1   81.98  ? 293 ARG B CD  1 
ATOM   5504 N  NE  . ARG C 1 123 ? -9.686  8.756   22.551  1   97.55  ? 293 ARG B NE  1 
ATOM   5505 C  CZ  . ARG C 1 123 ? -10.61  7.981   23.146  1   103.23 ? 293 ARG B CZ  1 
ATOM   5506 N  NH1 . ARG C 1 123 ? -11.809 7.801   22.604  1   97.43  ? 293 ARG B NH1 1 
ATOM   5507 N  NH2 . ARG C 1 123 ? -10.343 7.412   24.311  1   106.85 ? 293 ARG B NH2 1 
ATOM   5508 N  N   . MET C 1 124 ? -12.168 7.248   16.336  1   50.6   ? 294 MET B N   1 
ATOM   5509 C  CA  . MET C 1 124 ? -13.419 7.038   15.559  1   49.61  ? 294 MET B CA  1 
ATOM   5510 C  C   . MET C 1 124 ? -13.511 5.576   15.096  1   48.64  ? 294 MET B C   1 
ATOM   5511 O  O   . MET C 1 124 ? -14.627 5.045   15.037  1   49.42  ? 294 MET B O   1 
ATOM   5512 C  CB  . MET C 1 124 ? -13.5   7.983   14.355  1   48.22  ? 294 MET B CB  1 
ATOM   5513 C  CG  . MET C 1 124 ? -14.76  7.855   13.525  1   47.04  ? 294 MET B CG  1 
ATOM   5514 S  SD  . MET C 1 124 ? -16.259 8.321   14.407  1   49.26  ? 294 MET B SD  1 
ATOM   5515 C  CE  . MET C 1 124 ? -16.095 10.107  14.353  1   46.02  ? 294 MET B CE  1 
ATOM   5516 N  N   . GLU C 1 125 ? -12.374 4.954   14.804  1   46.69  ? 295 GLU B N   1 
ATOM   5517 C  CA  . GLU C 1 125 ? -12.373 3.539   14.367  1   45.83  ? 295 GLU B CA  1 
ATOM   5518 C  C   . GLU C 1 125 ? -13.034 2.703   15.461  1   51.4   ? 295 GLU B C   1 
ATOM   5519 O  O   . GLU C 1 125 ? -13.927 1.905   15.142  1   50.6   ? 295 GLU B O   1 
ATOM   5520 C  CB  . GLU C 1 125 ? -10.949 3.07    14.087  1   46.21  ? 295 GLU B CB  1 
ATOM   5521 C  CG  . GLU C 1 125 ? -10.817 1.562   13.907  1   45.07  ? 295 GLU B CG  1 
ATOM   5522 C  CD  . GLU C 1 125 ? -9.4    1.076   13.67   1   48.84  ? 295 GLU B CD  1 
ATOM   5523 O  OE1 . GLU C 1 125 ? -8.631  0.996   14.643  1   51.13  ? 295 GLU B OE1 1 
ATOM   5524 O  OE2 . GLU C 1 125 ? -9.066  0.772   12.511  1   46.56  ? 295 GLU B OE2 1 
ATOM   5525 N  N   . HIS C 1 126 ? -12.623 2.918   16.706  1   53.99  ? 296 HIS B N   1 
ATOM   5526 C  CA  . HIS C 1 126 ? -13.172 2.137   17.838  1   57.43  ? 296 HIS B CA  1 
ATOM   5527 C  C   . HIS C 1 126 ? -14.661 2.442   17.982  1   54.6   ? 296 HIS B C   1 
ATOM   5528 O  O   . HIS C 1 126 ? -15.439 1.535   18.301  1   54.95  ? 296 HIS B O   1 
ATOM   5529 C  CB  . HIS C 1 126 ? -12.384 2.453   19.11   1   66.37  ? 296 HIS B CB  1 
ATOM   5530 C  CG  . HIS C 1 126 ? -12.069 1.255   19.931  1   79.17  ? 296 HIS B CG  1 
ATOM   5531 N  ND1 . HIS C 1 126 ? -12.245 1.221   21.296  1   95.14  ? 296 HIS B ND1 1 
ATOM   5532 C  CD2 . HIS C 1 126 ? -11.6   0.055   19.586  1   84.02  ? 296 HIS B CD2 1 
ATOM   5533 C  CE1 . HIS C 1 126 ? -11.882 0.033   21.75   1   105.68 ? 296 HIS B CE1 1 
ATOM   5534 N  NE2 . HIS C 1 126 ? -11.49  -0.693  20.727  1   99.35  ? 296 HIS B NE2 1 
ATOM   5535 N  N   . LEU C 1 127 ? -15.037 3.697   17.77   1   51.95  ? 297 LEU B N   1 
ATOM   5536 C  CA  . LEU C 1 127 ? -16.456 4.091   17.914  1   49.11  ? 297 LEU B CA  1 
ATOM   5537 C  C   . LEU C 1 127 ? -17.266 3.356   16.845  1   47.1   ? 297 LEU B C   1 
ATOM   5538 O  O   . LEU C 1 127 ? -18.313 2.789   17.172  1   46.01  ? 297 LEU B O   1 
ATOM   5539 C  CB  . LEU C 1 127 ? -16.61  5.607   17.813  1   47.06  ? 297 LEU B CB  1 
ATOM   5540 C  CG  . LEU C 1 127 ? -18.019 6.156   18.05   1   45.77  ? 297 LEU B CG  1 
ATOM   5541 C  CD1 . LEU C 1 127 ? -18.56  5.676   19.381  1   43.03  ? 297 LEU B CD1 1 
ATOM   5542 C  CD2 . LEU C 1 127 ? -18.024 7.67    17.988  1   46.27  ? 297 LEU B CD2 1 
ATOM   5543 N  N   . VAL C 1 128 ? -16.765 3.358   15.617  1   44.67  ? 298 VAL B N   1 
ATOM   5544 C  CA  . VAL C 1 128 ? -17.496 2.682   14.557  1   43.85  ? 298 VAL B CA  1 
ATOM   5545 C  C   . VAL C 1 128 ? -17.557 1.174   14.823  1   46.37  ? 298 VAL B C   1 
ATOM   5546 O  O   . VAL C 1 128 ? -18.553 0.529   14.483  1   49.87  ? 298 VAL B O   1 
ATOM   5547 C  CB  . VAL C 1 128 ? -16.945 2.99    13.155  1   40.98  ? 298 VAL B CB  1 
ATOM   5548 C  CG1 . VAL C 1 128 ? -17.569 2.083   12.105  1   38.9   ? 298 VAL B CG1 1 
ATOM   5549 C  CG2 . VAL C 1 128 ? -17.153 4.449   12.767  1   41.35  ? 298 VAL B CG2 1 
ATOM   5550 N  N   . LEU C 1 129 ? -16.502 0.607   15.428  1   44.46  ? 299 LEU B N   1 
ATOM   5551 C  CA  . LEU C 1 129 ? -16.524 -0.808  15.751  1   42.37  ? 299 LEU B CA  1 
ATOM   5552 C  C   . LEU C 1 129 ? -17.549 -1.08   16.85   1   44.45  ? 299 LEU B C   1 
ATOM   5553 O  O   . LEU C 1 129 ? -18.211 -2.114  16.817  1   46.9   ? 299 LEU B O   1 
ATOM   5554 C  CB  . LEU C 1 129 ? -15.136 -1.32   16.123  1   43.04  ? 299 LEU B CB  1 
ATOM   5555 C  CG  . LEU C 1 129 ? -14.118 -1.454  14.981  1   42.38  ? 299 LEU B CG  1 
ATOM   5556 C  CD1 . LEU C 1 129 ? -12.732 -1.71   15.577  1   42.07  ? 299 LEU B CD1 1 
ATOM   5557 C  CD2 . LEU C 1 129 ? -14.491 -2.529  14      1   36.07  ? 299 LEU B CD2 1 
ATOM   5558 N  N   . LYS C 1 130 ? -17.67  -0.163  17.819  1   45.49  ? 300 LYS B N   1 
ATOM   5559 C  CA  . LYS C 1 130 ? -18.637 -0.3    18.899  1   49.34  ? 300 LYS B CA  1 
ATOM   5560 C  C   . LYS C 1 130 ? -20.059 -0.178  18.321  1   50.29  ? 300 LYS B C   1 
ATOM   5561 O  O   . LYS C 1 130 ? -20.918 -1.014  18.577  1   49.56  ? 300 LYS B O   1 
ATOM   5562 C  CB  . LYS C 1 130 ? -18.309 0.658   20.057  1   54.02  ? 300 LYS B CB  1 
ATOM   5563 C  CG  . LYS C 1 130 ? -19.456 0.882   21.076  1   65.03  ? 300 LYS B CG  1 
ATOM   5564 C  CD  . LYS C 1 130 ? -19.39  2.032   22.082  1   68.16  ? 300 LYS B CD  1 
ATOM   5565 C  CE  . LYS C 1 130 ? -20.732 2.438   22.636  1   68.98  ? 300 LYS B CE  1 
ATOM   5566 N  NZ  . LYS C 1 130 ? -20.682 3.287   23.838  1   65.98  ? 300 LYS B NZ  1 
ATOM   5567 N  N   . VAL C 1 131 ? -20.303 0.851   17.498  1   48.38  ? 301 VAL B N   1 
ATOM   5568 C  CA  . VAL C 1 131 ? -21.628 1.076   16.947  1   47.11  ? 301 VAL B CA  1 
ATOM   5569 C  C   . VAL C 1 131 ? -22.069 -0.121  16.097  1   45.97  ? 301 VAL B C   1 
ATOM   5570 O  O   . VAL C 1 131 ? -23.239 -0.511  16.138  1   44.27  ? 301 VAL B O   1 
ATOM   5571 C  CB  . VAL C 1 131 ? -21.668 2.401   16.159  1   45.56  ? 301 VAL B CB  1 
ATOM   5572 C  CG1 . VAL C 1 131 ? -22.869 2.492   15.232  1   44.16  ? 301 VAL B CG1 1 
ATOM   5573 C  CG2 . VAL C 1 131 ? -21.632 3.606   17.087  1   44.02  ? 301 VAL B CG2 1 
ATOM   5574 N  N   . LEU C 1 132 ? -21.129 -0.695  15.333  1   43.19  ? 302 LEU B N   1 
ATOM   5575 C  CA  . LEU C 1 132 ? -21.432 -1.792  14.444  1   41.74  ? 302 LEU B CA  1 
ATOM   5576 C  C   . LEU C 1 132 ? -21.347 -3.137  15.172  1   45.37  ? 302 LEU B C   1 
ATOM   5577 O  O   . LEU C 1 132 ? -21.754 -4.166  14.624  1   46.62  ? 302 LEU B O   1 
ATOM   5578 C  CB  . LEU C 1 132 ? -20.44  -1.68   13.293  1   42     ? 302 LEU B CB  1 
ATOM   5579 C  CG  . LEU C 1 132 ? -20.582 -0.433  12.403  1   45.53  ? 302 LEU B CG  1 
ATOM   5580 C  CD1 . LEU C 1 132 ? -19.564 -0.43   11.256  1   42.98  ? 302 LEU B CD1 1 
ATOM   5581 C  CD2 . LEU C 1 132 ? -21.952 -0.152  11.807  1   41.9   ? 302 LEU B CD2 1 
ATOM   5582 N  N   . ALA C 1 133 ? -20.819 -3.145  16.407  1   43.76  ? 303 ALA B N   1 
ATOM   5583 C  CA  . ALA C 1 133 ? -20.569 -4.374  17.151  1   42.38  ? 303 ALA B CA  1 
ATOM   5584 C  C   . ALA C 1 133 ? -19.726 -5.341  16.328  1   42.11  ? 303 ALA B C   1 
ATOM   5585 O  O   . ALA C 1 133 ? -19.999 -6.544  16.341  1   43.62  ? 303 ALA B O   1 
ATOM   5586 C  CB  . ALA C 1 133 ? -21.85  -5.036  17.621  1   38.89  ? 303 ALA B CB  1 
ATOM   5587 N  N   . PHE C 1 134 ? -18.711 -4.802  15.638  1   40.9   ? 304 PHE B N   1 
ATOM   5588 C  CA  . PHE C 1 134 ? -17.855 -5.56   14.733  1   45.34  ? 304 PHE B CA  1 
ATOM   5589 C  C   . PHE C 1 134 ? -18.621 -6.339  13.649  1   46.43  ? 304 PHE B C   1 
ATOM   5590 O  O   . PHE C 1 134 ? -18.126 -7.362  13.218  1   49.07  ? 304 PHE B O   1 
ATOM   5591 C  CB  . PHE C 1 134 ? -16.983 -6.547  15.52   1   45.67  ? 304 PHE B CB  1 
ATOM   5592 C  CG  . PHE C 1 134 ? -15.941 -5.913  16.421  1   52.23  ? 304 PHE B CG  1 
ATOM   5593 C  CD1 . PHE C 1 134 ? -16.302 -5.321  17.637  1   58.97  ? 304 PHE B CD1 1 
ATOM   5594 C  CD2 . PHE C 1 134 ? -14.596 -5.876  16.046  1   55.37  ? 304 PHE B CD2 1 
ATOM   5595 C  CE1 . PHE C 1 134 ? -15.342 -4.719  18.461  1   56.92  ? 304 PHE B CE1 1 
ATOM   5596 C  CE2 . PHE C 1 134 ? -13.644 -5.269  16.867  1   52.24  ? 304 PHE B CE2 1 
ATOM   5597 C  CZ  . PHE C 1 134 ? -14.013 -4.702  18.073  1   53.21  ? 304 PHE B CZ  1 
ATOM   5598 N  N   . ASP C 1 135 ? -19.795 -5.89   13.169  1   51.55  ? 305 ASP B N   1 
ATOM   5599 C  CA  . ASP C 1 135 ? -20.463 -6.614  12.09   1   49.91  ? 305 ASP B CA  1 
ATOM   5600 C  C   . ASP C 1 135 ? -19.986 -6.07   10.756  1   48.26  ? 305 ASP B C   1 
ATOM   5601 O  O   . ASP C 1 135 ? -20.692 -5.287  10.118  1   48.86  ? 305 ASP B O   1 
ATOM   5602 C  CB  . ASP C 1 135 ? -21.982 -6.578  12.14   1   51.32  ? 305 ASP B CB  1 
ATOM   5603 C  CG  . ASP C 1 135 ? -22.632 -7.472  13.178  1   67.71  ? 305 ASP B CG  1 
ATOM   5604 O  OD1 . ASP C 1 135 ? -21.897 -8.15   13.93   1   78.69  ? 305 ASP B OD1 1 
ATOM   5605 O  OD2 . ASP C 1 135 ? -23.876 -7.478  13.236  1   90.56  ? 305 ASP B OD2 1 
ATOM   5606 N  N   . LEU C 1 136 ? -18.787 -6.502  10.349  1   44.12  ? 306 LEU B N   1 
ATOM   5607 C  CA  . LEU C 1 136 ? -18.11  -5.874  9.225   1   44.15  ? 306 LEU B CA  1 
ATOM   5608 C  C   . LEU C 1 136 ? -18.287 -6.673  7.936   1   41.71  ? 306 LEU B C   1 
ATOM   5609 O  O   . LEU C 1 136 ? -18.087 -6.125  6.871   1   43.8   ? 306 LEU B O   1 
ATOM   5610 C  CB  . LEU C 1 136 ? -16.637 -5.644  9.567   1   45.88  ? 306 LEU B CB  1 
ATOM   5611 C  CG  . LEU C 1 136 ? -16.347 -4.558  10.612  1   49.17  ? 306 LEU B CG  1 
ATOM   5612 C  CD1 . LEU C 1 136 ? -14.963 -4.009  10.364  1   47.09  ? 306 LEU B CD1 1 
ATOM   5613 C  CD2 . LEU C 1 136 ? -17.372 -3.429  10.593  1   46.86  ? 306 LEU B CD2 1 
ATOM   5614 N  N   . ALA C 1 137 ? -18.663 -7.954  8.028   1   44.19  ? 307 ALA B N   1 
ATOM   5615 C  CA  . ALA C 1 137 ? -18.792 -8.838  6.87    1   40.03  ? 307 ALA B CA  1 
ATOM   5616 C  C   . ALA C 1 137 ? -20.136 -8.604  6.169   1   39.79  ? 307 ALA B C   1 
ATOM   5617 O  O   . ALA C 1 137 ? -20.944 -9.513  6.013   1   38.55  ? 307 ALA B O   1 
ATOM   5618 C  CB  . ALA C 1 137 ? -18.605 -10.266 7.311   1   37.2   ? 307 ALA B CB  1 
ATOM   5619 N  N   . ALA C 1 138 ? -20.37  -7.351  5.745   1   41.36  ? 308 ALA B N   1 
ATOM   5620 C  CA  . ALA C 1 138 ? -21.621 -6.951  5.121   1   41.39  ? 308 ALA B CA  1 
ATOM   5621 C  C   . ALA C 1 138 ? -21.639 -7.402  3.67    1   41.16  ? 308 ALA B C   1 
ATOM   5622 O  O   . ALA C 1 138 ? -20.634 -7.292  2.984   1   39.87  ? 308 ALA B O   1 
ATOM   5623 C  CB  . ALA C 1 138 ? -21.769 -5.445  5.186   1   38.76  ? 308 ALA B CB  1 
ATOM   5624 N  N   . PRO C 1 139 ? -22.793 -7.884  3.157   1   41.9   ? 309 PRO B N   1 
ATOM   5625 C  CA  . PRO C 1 139 ? -23.005 -8.049  1.717   1   41.33  ? 309 PRO B CA  1 
ATOM   5626 C  C   . PRO C 1 139 ? -23.044 -6.722  0.974   1   40.12  ? 309 PRO B C   1 
ATOM   5627 O  O   . PRO C 1 139 ? -23.715 -5.794  1.41    1   41.61  ? 309 PRO B O   1 
ATOM   5628 C  CB  . PRO C 1 139 ? -24.368 -8.737  1.597   1   38.42  ? 309 PRO B CB  1 
ATOM   5629 C  CG  . PRO C 1 139 ? -24.651 -9.269  2.966   1   39.6   ? 309 PRO B CG  1 
ATOM   5630 C  CD  . PRO C 1 139 ? -23.94  -8.345  3.941   1   41.86  ? 309 PRO B CD  1 
ATOM   5631 N  N   . THR C 1 140 ? -22.381 -6.691  -0.189  1   39.95  ? 310 THR B N   1 
ATOM   5632 C  CA  . THR C 1 140 ? -22.336 -5.53   -1.074  1   39.23  ? 310 THR B CA  1 
ATOM   5633 C  C   . THR C 1 140 ? -23.007 -5.792  -2.432  1   40.47  ? 310 THR B C   1 
ATOM   5634 O  O   . THR C 1 140 ? -23.242 -6.934  -2.872  1   43.62  ? 310 THR B O   1 
ATOM   5635 C  CB  . THR C 1 140 ? -20.871 -5.174  -1.315  1   38.7   ? 310 THR B CB  1 
ATOM   5636 O  OG1 . THR C 1 140 ? -20.253 -6.261  -2.022  1   38.76  ? 310 THR B OG1 1 
ATOM   5637 C  CG2 . THR C 1 140 ? -20.14  -4.822  -0.036  1   31.86  ? 310 THR B CG2 1 
ATOM   5638 N  N   . ILE C 1 141 ? -23.245 -4.703  -3.161  1   37.02  ? 311 ILE B N   1 
ATOM   5639 C  CA  . ILE C 1 141 ? -23.709 -4.872  -4.519  1   37.8   ? 311 ILE B CA  1 
ATOM   5640 C  C   . ILE C 1 141 ? -22.747 -5.793  -5.279  1   42.56  ? 311 ILE B C   1 
ATOM   5641 O  O   . ILE C 1 141 ? -23.201 -6.649  -6.048  1   46.82  ? 311 ILE B O   1 
ATOM   5642 C  CB  . ILE C 1 141 ? -23.856 -3.485  -5.149  1   36.32  ? 311 ILE B CB  1 
ATOM   5643 C  CG1 . ILE C 1 141 ? -25.137 -2.829  -4.65   1   35.86  ? 311 ILE B CG1 1 
ATOM   5644 C  CG2 . ILE C 1 141 ? -23.756 -3.544  -6.676  1   35.8   ? 311 ILE B CG2 1 
ATOM   5645 C  CD1 . ILE C 1 141 ? -25.163 -1.31   -4.715  1   34.61  ? 311 ILE B CD1 1 
ATOM   5646 N  N   . ASN C 1 142 ? -21.425 -5.632  -5.067  1   43.15  ? 312 ASN B N   1 
ATOM   5647 C  CA  . ASN C 1 142 ? -20.451 -6.378  -5.865  1   49.47  ? 312 ASN B CA  1 
ATOM   5648 C  C   . ASN C 1 142 ? -20.571 -7.878  -5.621  1   45.08  ? 312 ASN B C   1 
ATOM   5649 O  O   . ASN C 1 142 ? -20.484 -8.666  -6.571  1   46.58  ? 312 ASN B O   1 
ATOM   5650 C  CB  . ASN C 1 142 ? -18.996 -5.902  -5.76   1   54.44  ? 312 ASN B CB  1 
ATOM   5651 C  CG  . ASN C 1 142 ? -18.782 -4.59   -6.487  1   64.86  ? 312 ASN B CG  1 
ATOM   5652 O  OD1 . ASN C 1 142 ? -17.661 -4.304  -6.915  1   73.49  ? 312 ASN B OD1 1 
ATOM   5653 N  ND2 . ASN C 1 142 ? -19.823 -3.773  -6.664  1   65.57  ? 312 ASN B ND2 1 
ATOM   5654 N  N   . GLN C 1 143 ? -20.767 -8.252  -4.354  1   39.61  ? 313 GLN B N   1 
ATOM   5655 C  CA  . GLN C 1 143 ? -20.825 -9.66   -4.017  1   40.01  ? 313 GLN B CA  1 
ATOM   5656 C  C   . GLN C 1 143 ? -21.957 -10.352 -4.76   1   40.1   ? 313 GLN B C   1 
ATOM   5657 O  O   . GLN C 1 143 ? -21.873 -11.55  -5.041  1   43.43  ? 313 GLN B O   1 
ATOM   5658 C  CB  . GLN C 1 143 ? -20.99  -9.872  -2.525  1   39     ? 313 GLN B CB  1 
ATOM   5659 C  CG  . GLN C 1 143 ? -19.655 -9.952  -1.808  1   37.38  ? 313 GLN B CG  1 
ATOM   5660 C  CD  . GLN C 1 143 ? -19.837 -9.795  -0.321  1   39.95  ? 313 GLN B CD  1 
ATOM   5661 O  OE1 . GLN C 1 143 ? -20.408 -10.647 0.372   1   43.11  ? 313 GLN B OE1 1 
ATOM   5662 N  NE2 . GLN C 1 143 ? -19.377 -8.664  0.181   1   42.58  ? 313 GLN B NE2 1 
ATOM   5663 N  N   . PHE C 1 144 ? -23.009 -9.594  -5.076  1   40.57  ? 314 PHE B N   1 
ATOM   5664 C  CA  . PHE C 1 144 ? -24.141 -10.155 -5.788  1   39.48  ? 314 PHE B CA  1 
ATOM   5665 C  C   . PHE C 1 144 ? -23.852 -10.148 -7.277  1   41.59  ? 314 PHE B C   1 
ATOM   5666 O  O   . PHE C 1 144 ? -24.058 -11.176 -7.941  1   45.58  ? 314 PHE B O   1 
ATOM   5667 C  CB  . PHE C 1 144 ? -25.396 -9.38   -5.425  1   38.79  ? 314 PHE B CB  1 
ATOM   5668 C  CG  . PHE C 1 144 ? -25.97  -9.824  -4.095  1   41.08  ? 314 PHE B CG  1 
ATOM   5669 C  CD1 . PHE C 1 144 ? -26.565 -11.088 -3.967  1   39.91  ? 314 PHE B CD1 1 
ATOM   5670 C  CD2 . PHE C 1 144 ? -25.978 -8.946  -3.006  1   41.67  ? 314 PHE B CD2 1 
ATOM   5671 C  CE1 . PHE C 1 144 ? -27.124 -11.474 -2.754  1   39.01  ? 314 PHE B CE1 1 
ATOM   5672 C  CE2 . PHE C 1 144 ? -26.565 -9.336  -1.798  1   41.8   ? 314 PHE B CE2 1 
ATOM   5673 C  CZ  . PHE C 1 144 ? -27.138 -10.592 -1.673  1   38.2   ? 314 PHE B CZ  1 
ATOM   5674 N  N   . LEU C 1 145 ? -23.395 -8.986  -7.777  1   39.28  ? 315 LEU B N   1 
ATOM   5675 C  CA  . LEU C 1 145 ? -23.009 -8.814  -9.169  1   38.99  ? 315 LEU B CA  1 
ATOM   5676 C  C   . LEU C 1 145 ? -22.076 -9.921  -9.666  1   40.11  ? 315 LEU B C   1 
ATOM   5677 O  O   . LEU C 1 145 ? -22.298 -10.505 -10.731 1   40.44  ? 315 LEU B O   1 
ATOM   5678 C  CB  . LEU C 1 145 ? -22.346 -7.453  -9.326  1   38.77  ? 315 LEU B CB  1 
ATOM   5679 C  CG  . LEU C 1 145 ? -23.261 -6.265  -9.624  1   39.06  ? 315 LEU B CG  1 
ATOM   5680 C  CD1 . LEU C 1 145 ? -22.313 -5.086  -9.828  1   37.78  ? 315 LEU B CD1 1 
ATOM   5681 C  CD2 . LEU C 1 145 ? -24.152 -6.459  -10.87  1   37.18  ? 315 LEU B CD2 1 
ATOM   5682 N  N   . THR C 1 146 ? -20.992 -10.185 -8.928  1   40.07  ? 316 THR B N   1 
ATOM   5683 C  CA  . THR C 1 146 ? -20.035 -11.187 -9.389  1   39.58  ? 316 THR B CA  1 
ATOM   5684 C  C   . THR C 1 146 ? -20.741 -12.531 -9.55   1   41.5   ? 316 THR B C   1 
ATOM   5685 O  O   . THR C 1 146 ? -20.509 -13.245 -10.513 1   46.51  ? 316 THR B O   1 
ATOM   5686 C  CB  . THR C 1 146 ? -18.75  -11.254 -8.558  1   35.18  ? 316 THR B CB  1 
ATOM   5687 O  OG1 . THR C 1 146 ? -19.049 -11.573 -7.206  1   37.53  ? 316 THR B OG1 1 
ATOM   5688 C  CG2 . THR C 1 146 ? -18.033 -9.917  -8.516  1   31.09  ? 316 THR B CG2 1 
ATOM   5689 N  N   . GLN C 1 147 ? -21.67  -12.854 -8.652  1   42.15  ? 317 GLN B N   1 
ATOM   5690 C  CA  . GLN C 1 147 ? -22.426 -14.078 -8.862  1   41.92  ? 317 GLN B CA  1 
ATOM   5691 C  C   . GLN C 1 147 ? -23.351 -13.984 -10.076 1   44.96  ? 317 GLN B C   1 
ATOM   5692 O  O   . GLN C 1 147 ? -23.498 -14.965 -10.805 1   47.42  ? 317 GLN B O   1 
ATOM   5693 C  CB  . GLN C 1 147 ? -23.232 -14.366 -7.618  1   39.7   ? 317 GLN B CB  1 
ATOM   5694 C  CG  . GLN C 1 147 ? -22.355 -14.837 -6.484  1   41.59  ? 317 GLN B CG  1 
ATOM   5695 C  CD  . GLN C 1 147 ? -23.176 -15.264 -5.299  1   42.75  ? 317 GLN B CD  1 
ATOM   5696 O  OE1 . GLN C 1 147 ? -22.922 -14.814 -4.187  1   49.88  ? 317 GLN B OE1 1 
ATOM   5697 N  NE2 . GLN C 1 147 ? -24.145 -16.14  -5.513  1   41.32  ? 317 GLN B NE2 1 
ATOM   5698 N  N   . TYR C 1 148 ? -23.984 -12.818 -10.288 1   43.07  ? 318 TYR B N   1 
ATOM   5699 C  CA  . TYR C 1 148 ? -24.907 -12.676 -11.405 1   41.42  ? 318 TYR B CA  1 
ATOM   5700 C  C   . TYR C 1 148 ? -24.127 -12.874 -12.698 1   41.71  ? 318 TYR B C   1 
ATOM   5701 O  O   . TYR C 1 148 ? -24.642 -13.39  -13.678 1   40.73  ? 318 TYR B O   1 
ATOM   5702 C  CB  . TYR C 1 148 ? -25.653 -11.336 -11.372 1   38.99  ? 318 TYR B CB  1 
ATOM   5703 C  CG  . TYR C 1 148 ? -26.58  -11.102 -10.186 1   37.68  ? 318 TYR B CG  1 
ATOM   5704 C  CD1 . TYR C 1 148 ? -26.934 -12.123 -9.313  1   37.45  ? 318 TYR B CD1 1 
ATOM   5705 C  CD2 . TYR C 1 148 ? -27.135 -9.851  -9.943  1   39.97  ? 318 TYR B CD2 1 
ATOM   5706 C  CE1 . TYR C 1 148 ? -27.787 -11.913 -8.238  1   36.7   ? 318 TYR B CE1 1 
ATOM   5707 C  CE2 . TYR C 1 148 ? -27.993 -9.624  -8.868  1   39.49  ? 318 TYR B CE2 1 
ATOM   5708 C  CZ  . TYR C 1 148 ? -28.313 -10.654 -8.002  1   38.23  ? 318 TYR B CZ  1 
ATOM   5709 O  OH  . TYR C 1 148 ? -29.13  -10.42  -6.934  1   37.69  ? 318 TYR B OH  1 
ATOM   5710 N  N   . PHE C 1 149 ? -22.865 -12.443 -12.684 1   45.91  ? 319 PHE B N   1 
ATOM   5711 C  CA  . PHE C 1 149 ? -22.041 -12.438 -13.882 1   44.08  ? 319 PHE B CA  1 
ATOM   5712 C  C   . PHE C 1 149 ? -21.829 -13.864 -14.394 1   43.88  ? 319 PHE B C   1 
ATOM   5713 O  O   . PHE C 1 149 ? -21.65  -14.053 -15.588 1   46.96  ? 319 PHE B O   1 
ATOM   5714 C  CB  . PHE C 1 149 ? -20.682 -11.787 -13.636 1   42.9   ? 319 PHE B CB  1 
ATOM   5715 C  CG  . PHE C 1 149 ? -20.629 -10.287 -13.424 1   42.46  ? 319 PHE B CG  1 
ATOM   5716 C  CD1 . PHE C 1 149 ? -21.698 -9.464  -13.794 1   43.13  ? 319 PHE B CD1 1 
ATOM   5717 C  CD2 . PHE C 1 149 ? -19.484 -9.706  -12.868 1   38.27  ? 319 PHE B CD2 1 
ATOM   5718 C  CE1 . PHE C 1 149 ? -21.63  -8.083  -13.598 1   41.81  ? 319 PHE B CE1 1 
ATOM   5719 C  CE2 . PHE C 1 149 ? -19.409 -8.331  -12.691 1   37.67  ? 319 PHE B CE2 1 
ATOM   5720 C  CZ  . PHE C 1 149 ? -20.48  -7.522  -13.053 1   42.63  ? 319 PHE B CZ  1 
ATOM   5721 N  N   . LEU C 1 150 ? -21.876 -14.878 -13.525 1   41.72  ? 320 LEU B N   1 
ATOM   5722 C  CA  . LEU C 1 150 ? -21.696 -16.247 -14.001 1   44.88  ? 320 LEU B CA  1 
ATOM   5723 C  C   . LEU C 1 150 ? -22.861 -16.733 -14.879 1   46.91  ? 320 LEU B C   1 
ATOM   5724 O  O   . LEU C 1 150 ? -22.823 -17.836 -15.404 1   45.96  ? 320 LEU B O   1 
ATOM   5725 C  CB  . LEU C 1 150 ? -21.477 -17.158 -12.798 1   41.82  ? 320 LEU B CB  1 
ATOM   5726 C  CG  . LEU C 1 150 ? -20.299 -16.768 -11.911 1   43.95  ? 320 LEU B CG  1 
ATOM   5727 C  CD1 . LEU C 1 150 ? -20.291 -17.548 -10.608 1   41.61  ? 320 LEU B CD1 1 
ATOM   5728 C  CD2 . LEU C 1 150 ? -18.987 -16.896 -12.681 1   41.91  ? 320 LEU B CD2 1 
ATOM   5729 N  N   . HIS C 1 151 ? -23.905 -15.926 -14.989 1   48.22  ? 321 HIS B N   1 
ATOM   5730 C  CA  . HIS C 1 151 ? -25.102 -16.363 -15.75  1   52.45  ? 321 HIS B CA  1 
ATOM   5731 C  C   . HIS C 1 151 ? -25.069 -15.704 -17.127 1   58.21  ? 321 HIS B C   1 
ATOM   5732 O  O   . HIS C 1 151 ? -26.079 -15.75  -17.846 1   62.14  ? 321 HIS B O   1 
ATOM   5733 C  CB  . HIS C 1 151 ? -26.379 -16.059 -14.966 1   50.85  ? 321 HIS B CB  1 
ATOM   5734 C  CG  . HIS C 1 151 ? -26.535 -16.837 -13.706 1   48.29  ? 321 HIS B CG  1 
ATOM   5735 N  ND1 . HIS C 1 151 ? -27.51  -17.794 -13.549 1   46.52  ? 321 HIS B ND1 1 
ATOM   5736 C  CD2 . HIS C 1 151 ? -25.869 -16.793 -12.551 1   46.09  ? 321 HIS B CD2 1 
ATOM   5737 C  CE1 . HIS C 1 151 ? -27.422 -18.309 -12.335 1   47.69  ? 321 HIS B CE1 1 
ATOM   5738 N  NE2 . HIS C 1 151 ? -26.431 -17.716 -11.712 1   45.55  ? 321 HIS B NE2 1 
ATOM   5739 N  N   . GLN C 1 152 ? -23.93  -15.117 -17.48  1   55.89  ? 322 GLN B N   1 
ATOM   5740 C  CA  . GLN C 1 152 ? -23.785 -14.531 -18.829 1   61.68  ? 322 GLN B CA  1 
ATOM   5741 C  C   . GLN C 1 152 ? -23.427 -15.652 -19.8   1   73.36  ? 322 GLN B C   1 
ATOM   5742 O  O   . GLN C 1 152 ? -22.616 -16.518 -19.429 1   67.48  ? 322 GLN B O   1 
ATOM   5743 C  CB  . GLN C 1 152 ? -22.657 -13.518 -18.972 1   61.67  ? 322 GLN B CB  1 
ATOM   5744 C  CG  . GLN C 1 152 ? -22.771 -12.263 -18.118 1   66.46  ? 322 GLN B CG  1 
ATOM   5745 C  CD  . GLN C 1 152 ? -21.471 -11.493 -18.092 1   73.8   ? 322 GLN B CD  1 
ATOM   5746 O  OE1 . GLN C 1 152 ? -21.277 -10.532 -18.841 1   79.69  ? 322 GLN B OE1 1 
ATOM   5747 N  NE2 . GLN C 1 152 ? -20.55  -11.937 -17.251 1   58.01  ? 322 GLN B NE2 1 
ATOM   5748 N  N   . GLN C 1 153 ? -24.012 -15.621 -20.993 1   81.19  ? 323 GLN B N   1 
ATOM   5749 C  CA  . GLN C 1 153 ? -23.695 -16.626 -22.034 1   98.31  ? 323 GLN B CA  1 
ATOM   5750 C  C   . GLN C 1 153 ? -23.553 -15.895 -23.376 1   101.13 ? 323 GLN B C   1 
ATOM   5751 O  O   . GLN C 1 153 ? -24.581 -15.705 -24.058 1   99.21  ? 323 GLN B O   1 
ATOM   5752 C  CB  . GLN C 1 153 ? -24.803 -17.675 -22.082 1   113.05 ? 323 GLN B CB  1 
ATOM   5753 C  CG  . GLN C 1 153 ? -24.887 -18.541 -20.831 1   120.62 ? 323 GLN B CG  1 
ATOM   5754 C  CD  . GLN C 1 153 ? -26.034 -19.526 -20.864 1   119.76 ? 323 GLN B CD  1 
ATOM   5755 O  OE1 . GLN C 1 153 ? -27.043 -19.321 -21.548 1   120.6  ? 323 GLN B OE1 1 
ATOM   5756 N  NE2 . GLN C 1 153 ? -25.888 -20.611 -20.118 1   110.59 ? 323 GLN B NE2 1 
ATOM   5757 N  N   . PRO C 1 154 ? -22.34  -15.456 -23.774 1   89.07  ? 324 PRO B N   1 
ATOM   5758 C  CA  . PRO C 1 154 ? -21.145 -15.702 -22.986 1   79.76  ? 324 PRO B CA  1 
ATOM   5759 C  C   . PRO C 1 154 ? -20.707 -14.544 -22.111 1   67.72  ? 324 PRO B C   1 
ATOM   5760 O  O   . PRO C 1 154 ? -21.337 -13.476 -22.113 1   59.45  ? 324 PRO B O   1 
ATOM   5761 C  CB  . PRO C 1 154 ? -20.179 -15.926 -24.142 1   78.79  ? 324 PRO B CB  1 
ATOM   5762 C  CG  . PRO C 1 154 ? -20.568 -14.863 -25.141 1   79.74  ? 324 PRO B CG  1 
ATOM   5763 C  CD  . PRO C 1 154 ? -22.076 -14.742 -25.008 1   79.18  ? 324 PRO B CD  1 
ATOM   5764 N  N   . ALA C 1 155 ? -19.623 -14.752 -21.369 1   60.61  ? 325 ALA B N   1 
ATOM   5765 C  CA  . ALA C 1 155 ? -19.086 -13.667 -20.526 1   57.34  ? 325 ALA B CA  1 
ATOM   5766 C  C   . ALA C 1 155 ? -18.732 -12.484 -21.413 1   56.04  ? 325 ALA B C   1 
ATOM   5767 O  O   . ALA C 1 155 ? -18.269 -12.688 -22.545 1   61.6   ? 325 ALA B O   1 
ATOM   5768 C  CB  . ALA C 1 155 ? -17.898 -14.154 -19.756 1   54.89  ? 325 ALA B CB  1 
ATOM   5769 N  N   . ASN C 1 156 ? -18.931 -11.281 -20.902 1   50.47  ? 326 ASN B N   1 
ATOM   5770 C  CA  . ASN C 1 156 ? -18.704 -10.095 -21.701 1   51.47  ? 326 ASN B CA  1 
ATOM   5771 C  C   . ASN C 1 156 ? -18.263 -9.016  -20.732 1   53.29  ? 326 ASN B C   1 
ATOM   5772 O  O   . ASN C 1 156 ? -19.053 -8.649  -19.874 1   58.43  ? 326 ASN B O   1 
ATOM   5773 C  CB  . ASN C 1 156 ? -19.946 -9.677  -22.487 1   50.78  ? 326 ASN B CB  1 
ATOM   5774 C  CG  . ASN C 1 156 ? -19.776 -8.393  -23.272 1   55.34  ? 326 ASN B CG  1 
ATOM   5775 O  OD1 . ASN C 1 156 ? -19.215 -7.416  -22.753 1   60.93  ? 326 ASN B OD1 1 
ATOM   5776 N  ND2 . ASN C 1 156 ? -20.229 -8.362  -24.522 1   55.13  ? 326 ASN B ND2 1 
ATOM   5777 N  N   . CYS C 1 157 ? -17.035 -8.502  -20.907 1   55.49  ? 327 CYS B N   1 
ATOM   5778 C  CA  . CYS C 1 157 ? -16.358 -7.652  -19.93  1   53.08  ? 327 CYS B CA  1 
ATOM   5779 C  C   . CYS C 1 157 ? -16.962 -6.242  -19.889 1   50.14  ? 327 CYS B C   1 
ATOM   5780 O  O   . CYS C 1 157 ? -16.994 -5.645  -18.816 1   45.17  ? 327 CYS B O   1 
ATOM   5781 C  CB  . CYS C 1 157 ? -14.848 -7.704  -20.143 1   58.59  ? 327 CYS B CB  1 
ATOM   5782 S  SG  . CYS C 1 157 ? -14.363 -7.095  -21.782 1   73.45  ? 327 CYS B SG  1 
ATOM   5783 N  N   . LYS C 1 158 ? -17.483 -5.739  -21.03  1   51.54  ? 328 LYS B N   1 
ATOM   5784 C  CA  . LYS C 1 158 ? -18.226 -4.48   -21.084 1   51.23  ? 328 LYS B CA  1 
ATOM   5785 C  C   . LYS C 1 158 ? -19.521 -4.534  -20.262 1   50.08  ? 328 LYS B C   1 
ATOM   5786 O  O   . LYS C 1 158 ? -19.891 -3.548  -19.619 1   48.69  ? 328 LYS B O   1 
ATOM   5787 C  CB  . LYS C 1 158 ? -18.45  -4.067  -22.539 1   56.98  ? 328 LYS B CB  1 
ATOM   5788 C  CG  . LYS C 1 158 ? -17.441 -3.089  -23.102 1   63.12  ? 328 LYS B CG  1 
ATOM   5789 C  CD  . LYS C 1 158 ? -16.908 -3.47   -24.475 1   76.04  ? 328 LYS B CD  1 
ATOM   5790 C  CE  . LYS C 1 158 ? -17.91  -3.785  -25.549 1   82.31  ? 328 LYS B CE  1 
ATOM   5791 N  NZ  . LYS C 1 158 ? -18.525 -2.594  -26.142 1   85.93  ? 328 LYS B NZ  1 
ATOM   5792 N  N   . VAL C 1 159 ? -20.212 -5.686  -20.273 1   50.66  ? 329 VAL B N   1 
ATOM   5793 C  CA  . VAL C 1 159 ? -21.374 -5.907  -19.413 1   47.67  ? 329 VAL B CA  1 
ATOM   5794 C  C   . VAL C 1 159 ? -20.914 -5.822  -17.963 1   47.04  ? 329 VAL B C   1 
ATOM   5795 O  O   . VAL C 1 159 ? -21.485 -5.081  -17.169 1   46.38  ? 329 VAL B O   1 
ATOM   5796 C  CB  . VAL C 1 159 ? -22.106 -7.241  -19.687 1   47.7   ? 329 VAL B CB  1 
ATOM   5797 C  CG1 . VAL C 1 159 ? -23.176 -7.582  -18.644 1   45.93  ? 329 VAL B CG1 1 
ATOM   5798 C  CG2 . VAL C 1 159 ? -22.703 -7.287  -21.088 1   47.16  ? 329 VAL B CG2 1 
ATOM   5799 N  N   . GLU C 1 160 ? -19.84  -6.559  -17.644 1   50.64  ? 330 GLU B N   1 
ATOM   5800 C  CA  . GLU C 1 160 ? -19.378 -6.67   -16.268 1   49.63  ? 330 GLU B CA  1 
ATOM   5801 C  C   . GLU C 1 160 ? -18.996 -5.293  -15.752 1   47.1   ? 330 GLU B C   1 
ATOM   5802 O  O   . GLU C 1 160 ? -19.466 -4.926  -14.686 1   47     ? 330 GLU B O   1 
ATOM   5803 C  CB  . GLU C 1 160 ? -18.234 -7.664  -16.111 1   49.8   ? 330 GLU B CB  1 
ATOM   5804 C  CG  . GLU C 1 160 ? -18.656 -9.063  -16.545 1   50.39  ? 330 GLU B CG  1 
ATOM   5805 C  CD  . GLU C 1 160 ? -17.7   -10.176 -16.164 1   52.87  ? 330 GLU B CD  1 
ATOM   5806 O  OE1 . GLU C 1 160 ? -16.818 -9.964  -15.301 1   57.19  ? 330 GLU B OE1 1 
ATOM   5807 O  OE2 . GLU C 1 160 ? -17.831 -11.266 -16.734 1   56.04  ? 330 GLU B OE2 1 
ATOM   5808 N  N   . SER C 1 161 ? -18.219 -4.535  -16.548 1   44.73  ? 331 SER B N   1 
ATOM   5809 C  CA  . SER C 1 161 ? -17.749 -3.22   -16.134 1   43.77  ? 331 SER B CA  1 
ATOM   5810 C  C   . SER C 1 161 ? -18.914 -2.227  -16.044 1   45.36  ? 331 SER B C   1 
ATOM   5811 O  O   . SER C 1 161 ? -18.958 -1.42   -15.122 1   43.35  ? 331 SER B O   1 
ATOM   5812 C  CB  . SER C 1 161 ? -16.613 -2.717  -16.998 1   43.54  ? 331 SER B CB  1 
ATOM   5813 O  OG  . SER C 1 161 ? -15.458 -3.543  -16.864 1   47.34  ? 331 SER B OG  1 
ATOM   5814 N  N   . LEU C 1 162 ? -19.856 -2.266  -17     1   45.5   ? 332 LEU B N   1 
ATOM   5815 C  CA  . LEU C 1 162 ? -20.925 -1.278  -16.979 1   46.25  ? 332 LEU B CA  1 
ATOM   5816 C  C   . LEU C 1 162 ? -21.822 -1.559  -15.777 1   45.96  ? 332 LEU B C   1 
ATOM   5817 O  O   . LEU C 1 162 ? -22.38  -0.643  -15.185 1   46.43  ? 332 LEU B O   1 
ATOM   5818 C  CB  . LEU C 1 162 ? -21.72  -1.265  -18.284 1   46.59  ? 332 LEU B CB  1 
ATOM   5819 C  CG  . LEU C 1 162 ? -22.879 -0.267  -18.359 1   46.45  ? 332 LEU B CG  1 
ATOM   5820 C  CD1 . LEU C 1 162 ? -22.408 1.148   -18.063 1   45.89  ? 332 LEU B CD1 1 
ATOM   5821 C  CD2 . LEU C 1 162 ? -23.535 -0.289  -19.729 1   47.14  ? 332 LEU B CD2 1 
ATOM   5822 N  N   . ALA C 1 163 ? -21.942 -2.833  -15.398 1   43.87  ? 333 ALA B N   1 
ATOM   5823 C  CA  . ALA C 1 163 ? -22.755 -3.157  -14.24  1   41.83  ? 333 ALA B CA  1 
ATOM   5824 C  C   . ALA C 1 163 ? -22.146 -2.583  -12.961 1   41.99  ? 333 ALA B C   1 
ATOM   5825 O  O   . ALA C 1 163 ? -22.884 -1.985  -12.181 1   42.12  ? 333 ALA B O   1 
ATOM   5826 C  CB  . ALA C 1 163 ? -22.945 -4.638  -14.155 1   40     ? 333 ALA B CB  1 
ATOM   5827 N  N   . MET C 1 164 ? -20.825 -2.779  -12.757 1   41.46  ? 334 MET B N   1 
ATOM   5828 C  CA  . MET C 1 164 ? -20.077 -2.282  -11.609 1   41.7   ? 334 MET B CA  1 
ATOM   5829 C  C   . MET C 1 164 ? -20.24  -0.765  -11.49  1   44.74  ? 334 MET B C   1 
ATOM   5830 O  O   . MET C 1 164 ? -20.382 -0.215  -10.38  1   45.16  ? 334 MET B O   1 
ATOM   5831 C  CB  . MET C 1 164 ? -18.582 -2.573  -11.752 1   46.41  ? 334 MET B CB  1 
ATOM   5832 C  CG  . MET C 1 164 ? -18.186 -4.034  -11.626 1   56.34  ? 334 MET B CG  1 
ATOM   5833 S  SD  . MET C 1 164 ? -18.412 -4.575  -9.917  1   70.86  ? 334 MET B SD  1 
ATOM   5834 C  CE  . MET C 1 164 ? -17.548 -6.152  -9.968  1   72.12  ? 334 MET B CE  1 
ATOM   5835 N  N   . PHE C 1 165 ? -20.185 -0.108  -12.66  1   44.93  ? 335 PHE B N   1 
ATOM   5836 C  CA  . PHE C 1 165 ? -20.263 1.336   -12.78  1   44.86  ? 335 PHE B CA  1 
ATOM   5837 C  C   . PHE C 1 165 ? -21.628 1.826   -12.306 1   47.75  ? 335 PHE B C   1 
ATOM   5838 O  O   . PHE C 1 165 ? -21.711 2.768   -11.515 1   55.11  ? 335 PHE B O   1 
ATOM   5839 C  CB  . PHE C 1 165 ? -20.058 1.727   -14.237 1   43.38  ? 335 PHE B CB  1 
ATOM   5840 C  CG  . PHE C 1 165 ? -20.395 3.168   -14.591 1   43.07  ? 335 PHE B CG  1 
ATOM   5841 C  CD1 . PHE C 1 165 ? -19.633 4.224   -14.107 1   42.48  ? 335 PHE B CD1 1 
ATOM   5842 C  CD2 . PHE C 1 165 ? -21.441 3.457   -15.465 1   43.64  ? 335 PHE B CD2 1 
ATOM   5843 C  CE1 . PHE C 1 165 ? -19.932 5.531   -14.471 1   44.63  ? 335 PHE B CE1 1 
ATOM   5844 C  CE2 . PHE C 1 165 ? -21.726 4.76    -15.856 1   44     ? 335 PHE B CE2 1 
ATOM   5845 C  CZ  . PHE C 1 165 ? -20.967 5.8     -15.362 1   45.49  ? 335 PHE B CZ  1 
ATOM   5846 N  N   . LEU C 1 166 ? -22.696 1.185   -12.793 1   45     ? 336 LEU B N   1 
ATOM   5847 C  CA  . LEU C 1 166 ? -24.047 1.591   -12.439 1   45.21  ? 336 LEU B CA  1 
ATOM   5848 C  C   . LEU C 1 166 ? -24.254 1.418   -10.934 1   48.11  ? 336 LEU B C   1 
ATOM   5849 O  O   . LEU C 1 166 ? -24.708 2.335   -10.242 1   51.92  ? 336 LEU B O   1 
ATOM   5850 C  CB  . LEU C 1 166 ? -25.037 0.797   -13.289 1   43.17  ? 336 LEU B CB  1 
ATOM   5851 C  CG  . LEU C 1 166 ? -25.007 1.145   -14.782 1   40.47  ? 336 LEU B CG  1 
ATOM   5852 C  CD1 . LEU C 1 166 ? -25.897 0.256   -15.607 1   39.85  ? 336 LEU B CD1 1 
ATOM   5853 C  CD2 . LEU C 1 166 ? -25.325 2.606   -15.016 1   39.69  ? 336 LEU B CD2 1 
ATOM   5854 N  N   . GLY C 1 167 ? -23.863 0.247   -10.428 1   46.3   ? 337 GLY B N   1 
ATOM   5855 C  CA  . GLY C 1 167 ? -23.895 -0.02   -9.003  1   44.92  ? 337 GLY B CA  1 
ATOM   5856 C  C   . GLY C 1 167 ? -23.132 1.04    -8.205  1   48.97  ? 337 GLY B C   1 
ATOM   5857 O  O   . GLY C 1 167 ? -23.58  1.41    -7.116  1   52.75  ? 337 GLY B O   1 
ATOM   5858 N  N   . GLU C 1 168 ? -21.978 1.514   -8.71   1   46.56  ? 338 GLU B N   1 
ATOM   5859 C  CA  . GLU C 1 168 ? -21.222 2.488   -7.926  1   48.77  ? 338 GLU B CA  1 
ATOM   5860 C  C   . GLU C 1 168 ? -21.972 3.819   -7.905  1   50.63  ? 338 GLU B C   1 
ATOM   5861 O  O   . GLU C 1 168 ? -22.027 4.499   -6.874  1   51.18  ? 338 GLU B O   1 
ATOM   5862 C  CB  . GLU C 1 168 ? -19.781 2.726   -8.37   1   45.06  ? 338 GLU B CB  1 
ATOM   5863 C  CG  . GLU C 1 168 ? -18.807 1.751   -7.729  1   43.55  ? 338 GLU B CG  1 
ATOM   5864 C  CD  . GLU C 1 168 ? -17.353 2.051   -8.034  1   44.85  ? 338 GLU B CD  1 
ATOM   5865 O  OE1 . GLU C 1 168 ? -16.963 3.235   -8.015  1   47.33  ? 338 GLU B OE1 1 
ATOM   5866 O  OE2 . GLU C 1 168 ? -16.607 1.094   -8.273  1   44.67  ? 338 GLU B OE2 1 
ATOM   5867 N  N   . LEU C 1 169 ? -22.556 4.172   -9.049  1   46.16  ? 339 LEU B N   1 
ATOM   5868 C  CA  . LEU C 1 169 ? -23.316 5.401   -9.111  1   51.05  ? 339 LEU B CA  1 
ATOM   5869 C  C   . LEU C 1 169 ? -24.353 5.436   -7.987  1   50.08  ? 339 LEU B C   1 
ATOM   5870 O  O   . LEU C 1 169 ? -24.56  6.48    -7.381  1   49.35  ? 339 LEU B O   1 
ATOM   5871 C  CB  . LEU C 1 169 ? -23.934 5.54    -10.499 1   53.26  ? 339 LEU B CB  1 
ATOM   5872 C  CG  . LEU C 1 169 ? -22.979 6.009   -11.599 1   51.85  ? 339 LEU B CG  1 
ATOM   5873 C  CD1 . LEU C 1 169 ? -23.773 6.23    -12.856 1   52.37  ? 339 LEU B CD1 1 
ATOM   5874 C  CD2 . LEU C 1 169 ? -22.242 7.278   -11.186 1   49.01  ? 339 LEU B CD2 1 
ATOM   5875 N  N   . SER C 1 170 ? -24.928 4.278   -7.655  1   47.64  ? 340 SER B N   1 
ATOM   5876 C  CA  . SER C 1 170 ? -26.036 4.202   -6.715  1   46.28  ? 340 SER B CA  1 
ATOM   5877 C  C   . SER C 1 170 ? -25.588 4.529   -5.286  1   47.16  ? 340 SER B C   1 
ATOM   5878 O  O   . SER C 1 170 ? -26.42  5.001   -4.508  1   54.51  ? 340 SER B O   1 
ATOM   5879 C  CB  . SER C 1 170 ? -26.727 2.851   -6.79   1   44.37  ? 340 SER B CB  1 
ATOM   5880 O  OG  . SER C 1 170 ? -26.098 1.889   -5.949  1   42.06  ? 340 SER B OG  1 
ATOM   5881 N  N   . LEU C 1 171 ? -24.309 4.264   -4.935  1   42.63  ? 341 LEU B N   1 
ATOM   5882 C  CA  . LEU C 1 171 ? -23.74  4.582   -3.626  1   40.89  ? 341 LEU B CA  1 
ATOM   5883 C  C   . LEU C 1 171 ? -23.824 6.082   -3.302  1   45.2   ? 341 LEU B C   1 
ATOM   5884 O  O   . LEU C 1 171 ? -23.768 6.473   -2.123  1   44.23  ? 341 LEU B O   1 
ATOM   5885 C  CB  . LEU C 1 171 ? -22.276 4.157   -3.604  1   40.69  ? 341 LEU B CB  1 
ATOM   5886 C  CG  . LEU C 1 171 ? -22.008 2.654   -3.777  1   42.55  ? 341 LEU B CG  1 
ATOM   5887 C  CD1 . LEU C 1 171 ? -20.494 2.408   -3.976  1   42.2   ? 341 LEU B CD1 1 
ATOM   5888 C  CD2 . LEU C 1 171 ? -22.515 1.808   -2.636  1   33.75  ? 341 LEU B CD2 1 
ATOM   5889 N  N   . ILE C 1 172 ? -23.906 6.928   -4.351  1   43.19  ? 342 ILE B N   1 
ATOM   5890 C  CA  . ILE C 1 172 ? -23.772 8.362   -4.174  1   44.81  ? 342 ILE B CA  1 
ATOM   5891 C  C   . ILE C 1 172 ? -25.061 8.953   -3.602  1   49.82  ? 342 ILE B C   1 
ATOM   5892 O  O   . ILE C 1 172 ? -25.017 9.929   -2.844  1   53.44  ? 342 ILE B O   1 
ATOM   5893 C  CB  . ILE C 1 172 ? -23.368 9.046   -5.491  1   42.96  ? 342 ILE B CB  1 
ATOM   5894 C  CG1 . ILE C 1 172 ? -22.028 8.556   -6.001  1   42.58  ? 342 ILE B CG1 1 
ATOM   5895 C  CG2 . ILE C 1 172 ? -23.345 10.562  -5.314  1   42.49  ? 342 ILE B CG2 1 
ATOM   5896 C  CD1 . ILE C 1 172 ? -20.848 9.292   -5.399  1   43.29  ? 342 ILE B CD1 1 
ATOM   5897 N  N   . ASP C 1 173 ? -26.204 8.378   -3.993  1   50.14  ? 343 ASP B N   1 
ATOM   5898 C  CA  . ASP C 1 173 ? -27.495 9.014   -3.778  1   51.59  ? 343 ASP B CA  1 
ATOM   5899 C  C   . ASP C 1 173 ? -28.347 8.207   -2.806  1   53.35  ? 343 ASP B C   1 
ATOM   5900 O  O   . ASP C 1 173 ? -29.014 7.267   -3.238  1   55.94  ? 343 ASP B O   1 
ATOM   5901 C  CB  . ASP C 1 173 ? -28.15  9.251   -5.118  1   50.49  ? 343 ASP B CB  1 
ATOM   5902 C  CG  . ASP C 1 173 ? -27.415 10.331  -5.89   1   56.45  ? 343 ASP B CG  1 
ATOM   5903 O  OD1 . ASP C 1 173 ? -27.205 11.422  -5.286  1   61.23  ? 343 ASP B OD1 1 
ATOM   5904 O  OD2 . ASP C 1 173 ? -27.03  10.065  -7.044  1   52.66  ? 343 ASP B OD2 1 
ATOM   5905 N  N   . ALA C 1 174 ? -28.3   8.582   -1.513  1   51.2   ? 344 ALA B N   1 
ATOM   5906 C  CA  . ALA C 1 174 ? -29.099 7.953   -0.472  1   50.35  ? 344 ALA B CA  1 
ATOM   5907 C  C   . ALA C 1 174 ? -30.565 7.981   -0.884  1   49.6   ? 344 ALA B C   1 
ATOM   5908 O  O   . ALA C 1 174 ? -31.275 7       -0.691  1   49.98  ? 344 ALA B O   1 
ATOM   5909 C  CB  . ALA C 1 174 ? -28.907 8.638   0.849   1   51.95  ? 344 ALA B CB  1 
ATOM   5910 N  N   . ASP C 1 175 ? -30.978 9.091   -1.492  1   48.7   ? 345 ASP B N   1 
ATOM   5911 C  CA  . ASP C 1 175 ? -32.276 9.169   -2.139  1   52.54  ? 345 ASP B CA  1 
ATOM   5912 C  C   . ASP C 1 175 ? -32.094 8.962   -3.643  1   55.35  ? 345 ASP B C   1 
ATOM   5913 O  O   . ASP C 1 175 ? -31.573 9.831   -4.335  1   57.29  ? 345 ASP B O   1 
ATOM   5914 C  CB  . ASP C 1 175 ? -32.981 10.484  -1.822  1   55.2   ? 345 ASP B CB  1 
ATOM   5915 C  CG  . ASP C 1 175 ? -34.343 10.679  -2.478  1   57.38  ? 345 ASP B CG  1 
ATOM   5916 O  OD1 . ASP C 1 175 ? -34.789 9.746   -3.167  1   55.7   ? 345 ASP B OD1 1 
ATOM   5917 O  OD2 . ASP C 1 175 ? -34.944 11.775  -2.318  1   60.91  ? 345 ASP B OD2 1 
ATOM   5918 N  N   . PRO C 1 176 ? -32.584 7.856   -4.244  1   55.19  ? 346 PRO B N   1 
ATOM   5919 C  CA  . PRO C 1 176 ? -33.404 6.865   -3.53   1   53.92  ? 346 PRO B CA  1 
ATOM   5920 C  C   . PRO C 1 176 ? -32.802 5.545   -3.06   1   53.11  ? 346 PRO B C   1 
ATOM   5921 O  O   . PRO C 1 176 ? -33.495 4.732   -2.458  1   58.23  ? 346 PRO B O   1 
ATOM   5922 C  CB  . PRO C 1 176 ? -34.427 6.589   -4.641  1   53.13  ? 346 PRO B CB  1 
ATOM   5923 C  CG  . PRO C 1 176 ? -33.605 6.634   -5.933  1   51.9   ? 346 PRO B CG  1 
ATOM   5924 C  CD  . PRO C 1 176 ? -32.452 7.596   -5.69   1   48.85  ? 346 PRO B CD  1 
ATOM   5925 N  N   . TYR C 1 177 ? -31.527 5.319   -3.343  1   48.74  ? 347 TYR B N   1 
ATOM   5926 C  CA  . TYR C 1 177 ? -31.004 3.96    -3.315  1   49.06  ? 347 TYR B CA  1 
ATOM   5927 C  C   . TYR C 1 177 ? -31.03  3.34    -1.913  1   47.8   ? 347 TYR B C   1 
ATOM   5928 O  O   . TYR C 1 177 ? -30.895 2.126   -1.755  1   45.87  ? 347 TYR B O   1 
ATOM   5929 C  CB  . TYR C 1 177 ? -29.671 3.912   -4.076  1   45.98  ? 347 TYR B CB  1 
ATOM   5930 C  CG  . TYR C 1 177 ? -29.925 4.216   -5.538  1   46.11  ? 347 TYR B CG  1 
ATOM   5931 C  CD1 . TYR C 1 177 ? -30.606 3.314   -6.357  1   44.93  ? 347 TYR B CD1 1 
ATOM   5932 C  CD2 . TYR C 1 177 ? -29.554 5.445   -6.067  1   49.21  ? 347 TYR B CD2 1 
ATOM   5933 C  CE1 . TYR C 1 177 ? -30.874 3.62    -7.682  1   46.42  ? 347 TYR B CE1 1 
ATOM   5934 C  CE2 . TYR C 1 177 ? -29.804 5.753   -7.391  1   48.67  ? 347 TYR B CE2 1 
ATOM   5935 C  CZ  . TYR C 1 177 ? -30.469 4.845   -8.194  1   48.86  ? 347 TYR B CZ  1 
ATOM   5936 O  OH  . TYR C 1 177 ? -30.701 5.228   -9.483  1   54.06  ? 347 TYR B OH  1 
ATOM   5937 N  N   . LEU C 1 178 ? -31.204 4.166   -0.881  1   49.77  ? 348 LEU B N   1 
ATOM   5938 C  CA  . LEU C 1 178 ? -31.275 3.626   0.463   1   50.11  ? 348 LEU B CA  1 
ATOM   5939 C  C   . LEU C 1 178 ? -32.462 2.68    0.592   1   49.75  ? 348 LEU B C   1 
ATOM   5940 O  O   . LEU C 1 178 ? -32.5   1.858   1.494   1   51.64  ? 348 LEU B O   1 
ATOM   5941 C  CB  . LEU C 1 178 ? -31.383 4.752   1.482   1   51.73  ? 348 LEU B CB  1 
ATOM   5942 C  CG  . LEU C 1 178 ? -30.07  5.279   2.052   1   53.37  ? 348 LEU B CG  1 
ATOM   5943 C  CD1 . LEU C 1 178 ? -30.412 6.053   3.325   1   51.14  ? 348 LEU B CD1 1 
ATOM   5944 C  CD2 . LEU C 1 178 ? -29.06  4.167   2.327   1   49.51  ? 348 LEU B CD2 1 
ATOM   5945 N  N   . LYS C 1 179 ? -33.435 2.807   -0.304  1   50.89  ? 349 LYS B N   1 
ATOM   5946 C  CA  . LYS C 1 179 ? -34.634 2.011   -0.153  1   54.59  ? 349 LYS B CA  1 
ATOM   5947 C  C   . LYS C 1 179 ? -34.49  0.638   -0.812  1   53.75  ? 349 LYS B C   1 
ATOM   5948 O  O   . LYS C 1 179 ? -35.428 -0.141  -0.744  1   58.42  ? 349 LYS B O   1 
ATOM   5949 C  CB  . LYS C 1 179 ? -35.828 2.842   -0.625  1   60.22  ? 349 LYS B CB  1 
ATOM   5950 C  CG  . LYS C 1 179 ? -35.997 3.005   -2.123  1   67.25  ? 349 LYS B CG  1 
ATOM   5951 C  CD  . LYS C 1 179 ? -37.248 3.775   -2.577  1   67.86  ? 349 LYS B CD  1 
ATOM   5952 C  CE  . LYS C 1 179 ? -37.169 5.246   -2.363  1   68.82  ? 349 LYS B CE  1 
ATOM   5953 N  NZ  . LYS C 1 179 ? -37.909 5.956   -3.412  1   68.08  ? 349 LYS B NZ  1 
ATOM   5954 N  N   . TYR C 1 180 ? -33.346 0.339   -1.442  1   47.37  ? 350 TYR B N   1 
ATOM   5955 C  CA  . TYR C 1 180 ? -33.193 -0.925  -2.148  1   45.23  ? 350 TYR B CA  1 
ATOM   5956 C  C   . TYR C 1 180 ? -32.013 -1.697  -1.566  1   47.07  ? 350 TYR B C   1 
ATOM   5957 O  O   . TYR C 1 180 ? -30.99  -1.105  -1.245  1   46.57  ? 350 TYR B O   1 
ATOM   5958 C  CB  . TYR C 1 180 ? -32.964 -0.735  -3.644  1   43.37  ? 350 TYR B CB  1 
ATOM   5959 C  CG  . TYR C 1 180 ? -34.015 0.068   -4.404  1   46.75  ? 350 TYR B CG  1 
ATOM   5960 C  CD1 . TYR C 1 180 ? -35.287 -0.447  -4.65   1   47.46  ? 350 TYR B CD1 1 
ATOM   5961 C  CD2 . TYR C 1 180 ? -33.718 1.337   -4.907  1   44.6   ? 350 TYR B CD2 1 
ATOM   5962 C  CE1 . TYR C 1 180 ? -36.235 0.282   -5.364  1   50.38  ? 350 TYR B CE1 1 
ATOM   5963 C  CE2 . TYR C 1 180 ? -34.653 2.077   -5.612  1   45.42  ? 350 TYR B CE2 1 
ATOM   5964 C  CZ  . TYR C 1 180 ? -35.908 1.542   -5.846  1   48.23  ? 350 TYR B CZ  1 
ATOM   5965 O  OH  . TYR C 1 180 ? -36.79  2.259   -6.575  1   47.91  ? 350 TYR B OH  1 
ATOM   5966 N  N   . LEU C 1 181 ? -32.182 -3.019  -1.413  1   49.08  ? 351 LEU B N   1 
ATOM   5967 C  CA  . LEU C 1 181 ? -31.142 -3.911  -0.91   1   47.96  ? 351 LEU B CA  1 
ATOM   5968 C  C   . LEU C 1 181 ? -30.064 -4.078  -1.981  1   44.64  ? 351 LEU B C   1 
ATOM   5969 O  O   . LEU C 1 181 ? -30.324 -3.966  -3.18   1   42.86  ? 351 LEU B O   1 
ATOM   5970 C  CB  . LEU C 1 181 ? -31.719 -5.278  -0.526  1   46.82  ? 351 LEU B CB  1 
ATOM   5971 C  CG  . LEU C 1 181 ? -32.785 -5.331  0.577   1   47.09  ? 351 LEU B CG  1 
ATOM   5972 C  CD1 . LEU C 1 181 ? -33.626 -6.611  0.505   1   44.47  ? 351 LEU B CD1 1 
ATOM   5973 C  CD2 . LEU C 1 181 ? -32.171 -5.223  1.968   1   43.61  ? 351 LEU B CD2 1 
ATOM   5974 N  N   . PRO C 1 182 ? -28.817 -4.383  -1.577  1   43.35  ? 352 PRO B N   1 
ATOM   5975 C  CA  . PRO C 1 182 ? -27.748 -4.663  -2.535  1   41.74  ? 352 PRO B CA  1 
ATOM   5976 C  C   . PRO C 1 182 ? -28.132 -5.647  -3.634  1   41.24  ? 352 PRO B C   1 
ATOM   5977 O  O   . PRO C 1 182 ? -27.828 -5.408  -4.791  1   42.06  ? 352 PRO B O   1 
ATOM   5978 C  CB  . PRO C 1 182 ? -26.623 -5.228  -1.648  1   38.47  ? 352 PRO B CB  1 
ATOM   5979 C  CG  . PRO C 1 182 ? -26.84  -4.569  -0.318  1   38.18  ? 352 PRO B CG  1 
ATOM   5980 C  CD  . PRO C 1 182 ? -28.352 -4.392  -0.181  1   41.76  ? 352 PRO B CD  1 
ATOM   5981 N  N   . SER C 1 183 ? -28.774 -6.763  -3.269  1   41.52  ? 353 SER B N   1 
ATOM   5982 C  CA  . SER C 1 183 ? -29.123 -7.788  -4.247  1   41.83  ? 353 SER B CA  1 
ATOM   5983 C  C   . SER C 1 183 ? -29.983 -7.184  -5.362  1   46.03  ? 353 SER B C   1 
ATOM   5984 O  O   . SER C 1 183 ? -29.775 -7.533  -6.53   1   45.4   ? 353 SER B O   1 
ATOM   5985 C  CB  . SER C 1 183 ? -29.837 -8.971  -3.599  1   43.71  ? 353 SER B CB  1 
ATOM   5986 O  OG  . SER C 1 183 ? -31.158 -8.647  -3.171  1   41.37  ? 353 SER B OG  1 
ATOM   5987 N  N   . VAL C 1 184 ? -30.915 -6.276  -4.986  1   42.31  ? 354 VAL B N   1 
ATOM   5988 C  CA  . VAL C 1 184 ? -31.835 -5.655  -5.914  1   39.29  ? 354 VAL B CA  1 
ATOM   5989 C  C   . VAL C 1 184 ? -31.155 -4.6    -6.784  1   40.66  ? 354 VAL B C   1 
ATOM   5990 O  O   . VAL C 1 184 ? -31.465 -4.518  -7.966  1   46.37  ? 354 VAL B O   1 
ATOM   5991 C  CB  . VAL C 1 184 ? -33.1   -5.102  -5.24   1   39.46  ? 354 VAL B CB  1 
ATOM   5992 C  CG1 . VAL C 1 184 ? -33.949 -4.306  -6.235  1   35.88  ? 354 VAL B CG1 1 
ATOM   5993 C  CG2 . VAL C 1 184 ? -33.9   -6.241  -4.599  1   35.5   ? 354 VAL B CG2 1 
ATOM   5994 N  N   . ILE C 1 185 ? -30.281 -3.756  -6.237  1   38.59  ? 355 ILE B N   1 
ATOM   5995 C  CA  . ILE C 1 185 ? -29.581 -2.805  -7.096  1   42.7   ? 355 ILE B CA  1 
ATOM   5996 C  C   . ILE C 1 185 ? -28.654 -3.541  -8.082  1   45.54  ? 355 ILE B C   1 
ATOM   5997 O  O   . ILE C 1 185 ? -28.45  -3.121  -9.236  1   47.32  ? 355 ILE B O   1 
ATOM   5998 C  CB  . ILE C 1 185 ? -28.794 -1.777  -6.263  1   45.3   ? 355 ILE B CB  1 
ATOM   5999 C  CG1 . ILE C 1 185 ? -29.732 -0.934  -5.402  1   45.17  ? 355 ILE B CG1 1 
ATOM   6000 C  CG2 . ILE C 1 185 ? -27.881 -0.924  -7.161  1   41.29  ? 355 ILE B CG2 1 
ATOM   6001 C  CD1 . ILE C 1 185 ? -29.003 -0.172  -4.314  1   45.32  ? 355 ILE B CD1 1 
ATOM   6002 N  N   . ALA C 1 186 ? -28.063 -4.637  -7.612  1   40.47  ? 356 ALA B N   1 
ATOM   6003 C  CA  . ALA C 1 186 ? -27.163 -5.423  -8.426  1   40.48  ? 356 ALA B CA  1 
ATOM   6004 C  C   . ALA C 1 186 ? -27.932 -6.097  -9.56   1   41.8   ? 356 ALA B C   1 
ATOM   6005 O  O   . ALA C 1 186 ? -27.425 -6.19   -10.663 1   52.24  ? 356 ALA B O   1 
ATOM   6006 C  CB  . ALA C 1 186 ? -26.425 -6.405  -7.553  1   38.69  ? 356 ALA B CB  1 
ATOM   6007 N  N   . ALA C 1 187 ? -29.138 -6.594  -9.309  1   40.14  ? 357 ALA B N   1 
ATOM   6008 C  CA  . ALA C 1 187 ? -29.948 -7.136  -10.387 1   40.86  ? 357 ALA B CA  1 
ATOM   6009 C  C   . ALA C 1 187 ? -30.306 -6.046  -11.386 1   42.59  ? 357 ALA B C   1 
ATOM   6010 O  O   . ALA C 1 187 ? -30.254 -6.295  -12.573 1   41.75  ? 357 ALA B O   1 
ATOM   6011 C  CB  . ALA C 1 187 ? -31.22  -7.751  -9.853  1   42.9   ? 357 ALA B CB  1 
ATOM   6012 N  N   . ALA C 1 188 ? -30.693 -4.854  -10.908 1   44.23  ? 358 ALA B N   1 
ATOM   6013 C  CA  . ALA C 1 188 ? -31.102 -3.787  -11.816 1   44.83  ? 358 ALA B CA  1 
ATOM   6014 C  C   . ALA C 1 188 ? -29.917 -3.351  -12.686 1   43.33  ? 358 ALA B C   1 
ATOM   6015 O  O   . ALA C 1 188 ? -30.032 -3.258  -13.901 1   43.27  ? 358 ALA B O   1 
ATOM   6016 C  CB  . ALA C 1 188 ? -31.711 -2.627  -11.048 1   42.88  ? 358 ALA B CB  1 
ATOM   6017 N  N   . ALA C 1 189 ? -28.759 -3.122  -12.064 1   43.43  ? 359 ALA B N   1 
ATOM   6018 C  CA  . ALA C 1 189 ? -27.565 -2.723  -12.787 1   43.01  ? 359 ALA B CA  1 
ATOM   6019 C  C   . ALA C 1 189 ? -27.163 -3.816  -13.788 1   45.46  ? 359 ALA B C   1 
ATOM   6020 O  O   . ALA C 1 189 ? -26.789 -3.513  -14.923 1   45.81  ? 359 ALA B O   1 
ATOM   6021 C  CB  . ALA C 1 189 ? -26.481 -2.442  -11.778 1   40.59  ? 359 ALA B CB  1 
ATOM   6022 N  N   . PHE C 1 190 ? -27.268 -5.094  -13.39  1   44.97  ? 360 PHE B N   1 
ATOM   6023 C  CA  . PHE C 1 190 ? -26.905 -6.196  -14.272 1   44.46  ? 360 PHE B CA  1 
ATOM   6024 C  C   . PHE C 1 190 ? -27.796 -6.199  -15.503 1   43.34  ? 360 PHE B C   1 
ATOM   6025 O  O   . PHE C 1 190 ? -27.323 -6.427  -16.605 1   48.22  ? 360 PHE B O   1 
ATOM   6026 C  CB  . PHE C 1 190 ? -26.925 -7.572  -13.608 1   42.95  ? 360 PHE B CB  1 
ATOM   6027 C  CG  . PHE C 1 190 ? -26.477 -8.693  -14.53  1   43.95  ? 360 PHE B CG  1 
ATOM   6028 C  CD1 . PHE C 1 190 ? -25.158 -8.791  -14.958 1   43.32  ? 360 PHE B CD1 1 
ATOM   6029 C  CD2 . PHE C 1 190 ? -27.381 -9.659  -14.96  1   46.31  ? 360 PHE B CD2 1 
ATOM   6030 C  CE1 . PHE C 1 190 ? -24.757 -9.836  -15.787 1   45.12  ? 360 PHE B CE1 1 
ATOM   6031 C  CE2 . PHE C 1 190 ? -26.982 -10.697 -15.796 1   45.7   ? 360 PHE B CE2 1 
ATOM   6032 C  CZ  . PHE C 1 190 ? -25.671 -10.789 -16.206 1   45.94  ? 360 PHE B CZ  1 
ATOM   6033 N  N   . HIS C 1 191 ? -29.089 -5.956  -15.312 1   43.63  ? 361 HIS B N   1 
ATOM   6034 C  CA  . HIS C 1 191 ? -30.026 -6.014  -16.427 1   44.19  ? 361 HIS B CA  1 
ATOM   6035 C  C   . HIS C 1 191 ? -29.796 -4.806  -17.327 1   45.74  ? 361 HIS B C   1 
ATOM   6036 O  O   . HIS C 1 191 ? -29.827 -4.901  -18.552 1   48.13  ? 361 HIS B O   1 
ATOM   6037 C  CB  . HIS C 1 191 ? -31.483 -6.03   -15.962 1   41.55  ? 361 HIS B CB  1 
ATOM   6038 C  CG  . HIS C 1 191 ? -32.406 -5.71   -17.08  1   45.95  ? 361 HIS B CG  1 
ATOM   6039 N  ND1 . HIS C 1 191 ? -32.64  -6.623  -18.087 1   47.74  ? 361 HIS B ND1 1 
ATOM   6040 C  CD2 . HIS C 1 191 ? -33.082 -4.6    -17.409 1   46.22  ? 361 HIS B CD2 1 
ATOM   6041 C  CE1 . HIS C 1 191 ? -33.481 -6.106  -18.958 1   48.38  ? 361 HIS B CE1 1 
ATOM   6042 N  NE2 . HIS C 1 191 ? -33.754 -4.875  -18.568 1   49.25  ? 361 HIS B NE2 1 
ATOM   6043 N  N   . LEU C 1 192 ? -29.598 -3.66   -16.687 1   43.97  ? 362 LEU B N   1 
ATOM   6044 C  CA  . LEU C 1 192 ? -29.435 -2.428  -17.425 1   44.12  ? 362 LEU B CA  1 
ATOM   6045 C  C   . LEU C 1 192 ? -28.144 -2.503  -18.236 1   44.36  ? 362 LEU B C   1 
ATOM   6046 O  O   . LEU C 1 192 ? -28.13  -2.136  -19.401 1   45.54  ? 362 LEU B O   1 
ATOM   6047 C  CB  . LEU C 1 192 ? -29.473 -1.29   -16.417 1   41.78  ? 362 LEU B CB  1 
ATOM   6048 C  CG  . LEU C 1 192 ? -29.464 0.093   -17.044 1   46.34  ? 362 LEU B CG  1 
ATOM   6049 C  CD1 . LEU C 1 192 ? -30.525 0.12    -18.135 1   48.71  ? 362 LEU B CD1 1 
ATOM   6050 C  CD2 . LEU C 1 192 ? -29.71  1.129   -15.961 1   45.47  ? 362 LEU B CD2 1 
ATOM   6051 N  N   . ALA C 1 193 ? -27.085 -3.052  -17.635 1   44.61  ? 363 ALA B N   1 
ATOM   6052 C  CA  . ALA C 1 193 ? -25.807 -3.209  -18.314 1   46.98  ? 363 ALA B CA  1 
ATOM   6053 C  C   . ALA C 1 193 ? -25.977 -4.115  -19.524 1   49.43  ? 363 ALA B C   1 
ATOM   6054 O  O   . ALA C 1 193 ? -25.493 -3.805  -20.613 1   50.45  ? 363 ALA B O   1 
ATOM   6055 C  CB  . ALA C 1 193 ? -24.79  -3.79   -17.376 1   44.42  ? 363 ALA B CB  1 
ATOM   6056 N  N   . LEU C 1 194 ? -26.67  -5.233  -19.289 1   50.97  ? 364 LEU B N   1 
ATOM   6057 C  CA  . LEU C 1 194 ? -26.89  -6.262  -20.288 1   54.58  ? 364 LEU B CA  1 
ATOM   6058 C  C   . LEU C 1 194 ? -27.7   -5.69   -21.447 1   54.96  ? 364 LEU B C   1 
ATOM   6059 O  O   . LEU C 1 194 ? -27.347 -5.861  -22.611 1   57.47  ? 364 LEU B O   1 
ATOM   6060 C  CB  . LEU C 1 194 ? -27.614 -7.431  -19.619 1   57.2   ? 364 LEU B CB  1 
ATOM   6061 C  CG  . LEU C 1 194 ? -27.628 -8.73   -20.424 1   68.42  ? 364 LEU B CG  1 
ATOM   6062 C  CD1 . LEU C 1 194 ? -26.231 -9.359  -20.523 1   69.76  ? 364 LEU B CD1 1 
ATOM   6063 C  CD2 . LEU C 1 194 ? -28.601 -9.683  -19.784 1   73.59  ? 364 LEU B CD2 1 
ATOM   6064 N  N   . TYR C 1 195 ? -28.796 -5.01   -21.116 1   51.88  ? 365 TYR B N   1 
ATOM   6065 C  CA  . TYR C 1 195 ? -29.643 -4.454  -22.149 1   51.82  ? 365 TYR B CA  1 
ATOM   6066 C  C   . TYR C 1 195 ? -28.812 -3.469  -22.96  1   51.55  ? 365 TYR B C   1 
ATOM   6067 O  O   . TYR C 1 195 ? -28.773 -3.56   -24.171 1   52.44  ? 365 TYR B O   1 
ATOM   6068 C  CB  . TYR C 1 195 ? -30.91  -3.847  -21.549 1   50.37  ? 365 TYR B CB  1 
ATOM   6069 C  CG  . TYR C 1 195 ? -31.889 -3.344  -22.587 1   51.93  ? 365 TYR B CG  1 
ATOM   6070 C  CD1 . TYR C 1 195 ? -32.473 -4.215  -23.495 1   54.99  ? 365 TYR B CD1 1 
ATOM   6071 C  CD2 . TYR C 1 195 ? -32.266 -2.018  -22.623 1   54.25  ? 365 TYR B CD2 1 
ATOM   6072 C  CE1 . TYR C 1 195 ? -33.387 -3.777  -24.442 1   58.28  ? 365 TYR B CE1 1 
ATOM   6073 C  CE2 . TYR C 1 195 ? -33.2   -1.569  -23.542 1   60.46  ? 365 TYR B CE2 1 
ATOM   6074 C  CZ  . TYR C 1 195 ? -33.76  -2.441  -24.464 1   63.17  ? 365 TYR B CZ  1 
ATOM   6075 O  OH  . TYR C 1 195 ? -34.68  -1.954  -25.371 1   70.38  ? 365 TYR B OH  1 
ATOM   6076 N  N   . THR C 1 196 ? -28.104 -2.578  -22.271 1   49.91  ? 366 THR B N   1 
ATOM   6077 C  CA  . THR C 1 196 ? -27.386 -1.505  -22.938 1   50.63  ? 366 THR B CA  1 
ATOM   6078 C  C   . THR C 1 196 ? -26.336 -2.041  -23.911 1   49.49  ? 366 THR B C   1 
ATOM   6079 O  O   . THR C 1 196 ? -26.166 -1.466  -24.949 1   52.01  ? 366 THR B O   1 
ATOM   6080 C  CB  . THR C 1 196 ? -26.756 -0.534  -21.938 1   51.49  ? 366 THR B CB  1 
ATOM   6081 O  OG1 . THR C 1 196 ? -27.712 -0.03   -21.006 1   51.6   ? 366 THR B OG1 1 
ATOM   6082 C  CG2 . THR C 1 196 ? -26.12  0.645   -22.647 1   51.56  ? 366 THR B CG2 1 
ATOM   6083 N  N   . VAL C 1 197 ? -25.612 -3.11   -23.589 1   49.69  ? 367 VAL B N   1 
ATOM   6084 C  CA  . VAL C 1 197 ? -24.443 -3.523  -24.355 1   50.02  ? 367 VAL B CA  1 
ATOM   6085 C  C   . VAL C 1 197 ? -24.824 -4.536  -25.439 1   50.84  ? 367 VAL B C   1 
ATOM   6086 O  O   . VAL C 1 197 ? -24.322 -4.438  -26.567 1   54.43  ? 367 VAL B O   1 
ATOM   6087 C  CB  . VAL C 1 197 ? -23.319 -4.073  -23.448 1   51.65  ? 367 VAL B CB  1 
ATOM   6088 C  CG1 . VAL C 1 197 ? -22.217 -4.763  -24.248 1   54.06  ? 367 VAL B CG1 1 
ATOM   6089 C  CG2 . VAL C 1 197 ? -22.713 -2.995  -22.558 1   50.46  ? 367 VAL B CG2 1 
ATOM   6090 N  N   . THR C 1 198 ? -25.7   -5.5    -25.104 1   49.4   ? 368 THR B N   1 
ATOM   6091 C  CA  . THR C 1 198 ? -26.012 -6.653  -25.954 1   49.97  ? 368 THR B CA  1 
ATOM   6092 C  C   . THR C 1 198 ? -27.461 -6.638  -26.431 1   52.9   ? 368 THR B C   1 
ATOM   6093 O  O   . THR C 1 198 ? -27.827 -7.424  -27.301 1   54.9   ? 368 THR B O   1 
ATOM   6094 C  CB  . THR C 1 198 ? -25.802 -7.984  -25.23  1   48.91  ? 368 THR B CB  1 
ATOM   6095 O  OG1 . THR C 1 198 ? -26.768 -8.103  -24.182 1   50.24  ? 368 THR B OG1 1 
ATOM   6096 C  CG2 . THR C 1 198 ? -24.398 -8.18   -24.698 1   46.42  ? 368 THR B CG2 1 
ATOM   6097 N  N   . GLY C 1 199 ? -28.318 -5.851  -25.776 1   54.4   ? 369 GLY B N   1 
ATOM   6098 C  CA  . GLY C 1 199 ? -29.731 -5.885  -26.099 1   56.44  ? 369 GLY B CA  1 
ATOM   6099 C  C   . GLY C 1 199 ? -30.501 -6.917  -25.278 1   60.84  ? 369 GLY B C   1 
ATOM   6100 O  O   . GLY C 1 199 ? -31.723 -6.882  -25.265 1   66.02  ? 369 GLY B O   1 
ATOM   6101 N  N   . GLN C 1 200 ? -29.807 -7.85   -24.611 1   61.36  ? 370 GLN B N   1 
ATOM   6102 C  CA  . GLN C 1 200 ? -30.481 -8.948  -23.932 1   63.74  ? 370 GLN B CA  1 
ATOM   6103 C  C   . GLN C 1 200 ? -31.03  -8.48   -22.584 1   60.41  ? 370 GLN B C   1 
ATOM   6104 O  O   . GLN C 1 200 ? -30.747 -7.359  -22.176 1   60.31  ? 370 GLN B O   1 
ATOM   6105 C  CB  . GLN C 1 200 ? -29.501 -10.101 -23.739 1   73.17  ? 370 GLN B CB  1 
ATOM   6106 C  CG  . GLN C 1 200 ? -29.025 -10.763 -25.028 1   78.33  ? 370 GLN B CG  1 
ATOM   6107 C  CD  . GLN C 1 200 ? -27.86  -11.675 -24.725 1   86.77  ? 370 GLN B CD  1 
ATOM   6108 O  OE1 . GLN C 1 200 ? -27.974 -12.9   -24.793 1   94.37  ? 370 GLN B OE1 1 
ATOM   6109 N  NE2 . GLN C 1 200 ? -26.754 -11.088 -24.287 1   83.87  ? 370 GLN B NE2 1 
ATOM   6110 N  N   . SER C 1 201 ? -31.799 -9.355  -21.907 1   58.35  ? 371 SER B N   1 
ATOM   6111 C  CA  . SER C 1 201 ? -32.495 -9.065  -20.653 1   54.18  ? 371 SER B CA  1 
ATOM   6112 C  C   . SER C 1 201 ? -32.045 -9.989  -19.535 1   53.16  ? 371 SER B C   1 
ATOM   6113 O  O   . SER C 1 201 ? -31.521 -11.076 -19.764 1   53.99  ? 371 SER B O   1 
ATOM   6114 C  CB  . SER C 1 201 ? -33.965 -9.261  -20.778 1   54.03  ? 371 SER B CB  1 
ATOM   6115 O  OG  . SER C 1 201 ? -34.542 -8.139  -21.413 1   60.93  ? 371 SER B OG  1 
ATOM   6116 N  N   . TRP C 1 202 ? -32.374 -9.556  -18.32  1   54.08  ? 372 TRP B N   1 
ATOM   6117 C  CA  . TRP C 1 202 ? -32.316 -10.353 -17.102 1   53.66  ? 372 TRP B CA  1 
ATOM   6118 C  C   . TRP C 1 202 ? -32.765 -11.783 -17.406 1   54.08  ? 372 TRP B C   1 
ATOM   6119 O  O   . TRP C 1 202 ? -33.923 -12.024 -17.753 1   56.72  ? 372 TRP B O   1 
ATOM   6120 C  CB  . TRP C 1 202 ? -33.253 -9.687  -16.085 1   53.21  ? 372 TRP B CB  1 
ATOM   6121 C  CG  . TRP C 1 202 ? -33.332 -10.354 -14.744 1   51.48  ? 372 TRP B CG  1 
ATOM   6122 C  CD1 . TRP C 1 202 ? -34.417 -11.026 -14.27  1   51.26  ? 372 TRP B CD1 1 
ATOM   6123 C  CD2 . TRP C 1 202 ? -32.325 -10.401 -13.708 1   49.13  ? 372 TRP B CD2 1 
ATOM   6124 N  NE1 . TRP C 1 202 ? -34.165 -11.495 -13.01  1   51.2   ? 372 TRP B NE1 1 
ATOM   6125 C  CE2 . TRP C 1 202 ? -32.898 -11.128 -12.633 1   49.72  ? 372 TRP B CE2 1 
ATOM   6126 C  CE3 . TRP C 1 202 ? -31.012 -9.917  -13.575 1   47.24  ? 372 TRP B CE3 1 
ATOM   6127 C  CZ2 . TRP C 1 202 ? -32.203 -11.379 -11.449 1   46.11  ? 372 TRP B CZ2 1 
ATOM   6128 C  CZ3 . TRP C 1 202 ? -30.32  -10.171 -12.406 1   42.23  ? 372 TRP B CZ3 1 
ATOM   6129 C  CH2 . TRP C 1 202 ? -30.914 -10.886 -11.36  1   43.41  ? 372 TRP B CH2 1 
ATOM   6130 N  N   . PRO C 1 203 ? -31.859 -12.78  -17.326 1   50.28  ? 373 PRO B N   1 
ATOM   6131 C  CA  . PRO C 1 203 ? -32.186 -14.131 -17.796 1   48.9   ? 373 PRO B CA  1 
ATOM   6132 C  C   . PRO C 1 203 ? -33.01  -14.978 -16.839 1   49.92  ? 373 PRO B C   1 
ATOM   6133 O  O   . PRO C 1 203 ? -32.924 -14.829 -15.62  1   49.42  ? 373 PRO B O   1 
ATOM   6134 C  CB  . PRO C 1 203 ? -30.809 -14.747 -17.967 1   46.42  ? 373 PRO B CB  1 
ATOM   6135 C  CG  . PRO C 1 203 ? -30.013 -14.091 -16.857 1   45.01  ? 373 PRO B CG  1 
ATOM   6136 C  CD  . PRO C 1 203 ? -30.476 -12.632 -16.836 1   45.76  ? 373 PRO B CD  1 
ATOM   6137 N  N   . GLU C 1 204 ? -33.722 -15.936 -17.439 1   53.07  ? 374 GLU B N   1 
ATOM   6138 C  CA  . GLU C 1 204 ? -34.455 -16.983 -16.747 1   56.09  ? 374 GLU B CA  1 
ATOM   6139 C  C   . GLU C 1 204 ? -33.607 -17.595 -15.628 1   50.04  ? 374 GLU B C   1 
ATOM   6140 O  O   . GLU C 1 204 ? -34.114 -17.842 -14.537 1   47.16  ? 374 GLU B O   1 
ATOM   6141 C  CB  . GLU C 1 204 ? -34.871 -18.05  -17.767 1   64.6   ? 374 GLU B CB  1 
ATOM   6142 C  CG  . GLU C 1 204 ? -35.249 -19.414 -17.173 1   69.92  ? 374 GLU B CG  1 
ATOM   6143 C  CD  . GLU C 1 204 ? -36.462 -19.427 -16.258 1   75.29  ? 374 GLU B CD  1 
ATOM   6144 O  OE1 . GLU C 1 204 ? -37.287 -18.472 -16.25  1   80.45  ? 374 GLU B OE1 1 
ATOM   6145 O  OE2 . GLU C 1 204 ? -36.556 -20.419 -15.517 1   77.02  ? 374 GLU B OE2 1 
ATOM   6146 N  N   . SER C 1 205 ? -32.332 -17.863 -15.915 1   46.75  ? 375 SER B N   1 
ATOM   6147 C  CA  . SER C 1 205 ? -31.505 -18.564 -14.953 1   49.2   ? 375 SER B CA  1 
ATOM   6148 C  C   . SER C 1 205 ? -31.344 -17.721 -13.683 1   48.78  ? 375 SER B C   1 
ATOM   6149 O  O   . SER C 1 205 ? -31.16  -18.279 -12.599 1   50.82  ? 375 SER B O   1 
ATOM   6150 C  CB  . SER C 1 205 ? -30.188 -19.025 -15.552 1   48.87  ? 375 SER B CB  1 
ATOM   6151 O  OG  . SER C 1 205 ? -29.229 -17.971 -15.597 1   52.33  ? 375 SER B OG  1 
ATOM   6152 N  N   . LEU C 1 206 ? -31.455 -16.388 -13.798 1   46.81  ? 376 LEU B N   1 
ATOM   6153 C  CA  . LEU C 1 206 ? -31.338 -15.548 -12.61  1   44.75  ? 376 LEU B CA  1 
ATOM   6154 C  C   . LEU C 1 206 ? -32.693 -15.322 -11.944 1   44.22  ? 376 LEU B C   1 
ATOM   6155 O  O   . LEU C 1 206 ? -32.741 -15.012 -10.752 1   44.1   ? 376 LEU B O   1 
ATOM   6156 C  CB  . LEU C 1 206 ? -30.609 -14.241 -12.88  1   40.88  ? 376 LEU B CB  1 
ATOM   6157 C  CG  . LEU C 1 206 ? -29.088 -14.362 -12.968 1   41.54  ? 376 LEU B CG  1 
ATOM   6158 C  CD1 . LEU C 1 206 ? -28.512 -13.108 -13.572 1   41.09  ? 376 LEU B CD1 1 
ATOM   6159 C  CD2 . LEU C 1 206 ? -28.469 -14.658 -11.616 1   38.51  ? 376 LEU B CD2 1 
ATOM   6160 N  N   . VAL C 1 207 ? -33.771 -15.498 -12.71  1   43     ? 377 VAL B N   1 
ATOM   6161 C  CA  . VAL C 1 207 ? -35.086 -15.625 -12.104 1   46.89  ? 377 VAL B CA  1 
ATOM   6162 C  C   . VAL C 1 207 ? -35.082 -16.831 -11.158 1   49.11  ? 377 VAL B C   1 
ATOM   6163 O  O   . VAL C 1 207 ? -35.534 -16.729 -10.023 1   50.34  ? 377 VAL B O   1 
ATOM   6164 C  CB  . VAL C 1 207 ? -36.246 -15.688 -13.127 1   48.26  ? 377 VAL B CB  1 
ATOM   6165 C  CG1 . VAL C 1 207 ? -37.608 -15.759 -12.436 1   46.67  ? 377 VAL B CG1 1 
ATOM   6166 C  CG2 . VAL C 1 207 ? -36.216 -14.525 -14.114 1   44.08  ? 377 VAL B CG2 1 
ATOM   6167 N  N   . GLN C 1 208 ? -34.544 -17.97  -11.625 1   51.46  ? 378 GLN B N   1 
ATOM   6168 C  CA  . GLN C 1 208 ? -34.421 -19.179 -10.817 1   49.58  ? 378 GLN B CA  1 
ATOM   6169 C  C   . GLN C 1 208 ? -33.64  -18.887 -9.538  1   48.22  ? 378 GLN B C   1 
ATOM   6170 O  O   . GLN C 1 208 ? -34.071 -19.277 -8.463  1   49.16  ? 378 GLN B O   1 
ATOM   6171 C  CB  . GLN C 1 208 ? -33.758 -20.314 -11.596 1   49.07  ? 378 GLN B CB  1 
ATOM   6172 C  CG  . GLN C 1 208 ? -34.606 -20.873 -12.729 1   50.67  ? 378 GLN B CG  1 
ATOM   6173 C  CD  . GLN C 1 208 ? -35.906 -21.467 -12.221 1   58.22  ? 378 GLN B CD  1 
ATOM   6174 O  OE1 . GLN C 1 208 ? -36.978 -21.403 -12.856 1   55.83  ? 378 GLN B OE1 1 
ATOM   6175 N  NE2 . GLN C 1 208 ? -35.792 -22.098 -11.055 1   60.82  ? 378 GLN B NE2 1 
ATOM   6176 N  N   . LYS C 1 209 ? -32.504 -18.181 -9.656  1   48.53  ? 379 LYS B N   1 
ATOM   6177 C  CA  . LYS C 1 209 ? -31.587 -18.072 -8.532  1   49.15  ? 379 LYS B CA  1 
ATOM   6178 C  C   . LYS C 1 209 ? -32.111 -17.081 -7.493  1   48.81  ? 379 LYS B C   1 
ATOM   6179 O  O   . LYS C 1 209 ? -31.998 -17.331 -6.293  1   46.74  ? 379 LYS B O   1 
ATOM   6180 C  CB  . LYS C 1 209 ? -30.194 -17.681 -9.036  1   52.51  ? 379 LYS B CB  1 
ATOM   6181 C  CG  . LYS C 1 209 ? -29.145 -17.485 -7.941  1   52.27  ? 379 LYS B CG  1 
ATOM   6182 C  CD  . LYS C 1 209 ? -27.913 -16.716 -8.413  1   54.17  ? 379 LYS B CD  1 
ATOM   6183 C  CE  . LYS C 1 209 ? -26.712 -16.754 -7.477  1   51.74  ? 379 LYS B CE  1 
ATOM   6184 N  NZ  . LYS C 1 209 ? -26.256 -18.12  -7.195  1   49.28  ? 379 LYS B NZ  1 
ATOM   6185 N  N   . THR C 1 210 ? -32.674 -15.953 -7.966  1   47.82  ? 380 THR B N   1 
ATOM   6186 C  CA  . THR C 1 210 ? -32.957 -14.826 -7.084  1   46.34  ? 380 THR B CA  1 
ATOM   6187 C  C   . THR C 1 210 ? -34.423 -14.792 -6.673  1   44.95  ? 380 THR B C   1 
ATOM   6188 O  O   . THR C 1 210 ? -34.741 -14.23  -5.63   1   49.24  ? 380 THR B O   1 
ATOM   6189 C  CB  . THR C 1 210 ? -32.553 -13.495 -7.724  1   43.77  ? 380 THR B CB  1 
ATOM   6190 O  OG1 . THR C 1 210 ? -33.422 -13.192 -8.815  1   43.22  ? 380 THR B OG1 1 
ATOM   6191 C  CG2 . THR C 1 210 ? -31.12  -13.523 -8.211  1   40.69  ? 380 THR B CG2 1 
ATOM   6192 N  N   . GLY C 1 211 ? -35.305 -15.324 -7.514  1   42.61  ? 381 GLY B N   1 
ATOM   6193 C  CA  . GLY C 1 211 ? -36.727 -15.056 -7.357  1   43.85  ? 381 GLY B CA  1 
ATOM   6194 C  C   . GLY C 1 211 ? -37.162 -13.696 -7.918  1   44.72  ? 381 GLY B C   1 
ATOM   6195 O  O   . GLY C 1 211 ? -38.357 -13.449 -8.031  1   46.47  ? 381 GLY B O   1 
ATOM   6196 N  N   . TYR C 1 212 ? -36.219 -12.826 -8.312  1   43.08  ? 382 TYR B N   1 
ATOM   6197 C  CA  . TYR C 1 212 ? -36.602 -11.549 -8.892  1   43.62  ? 382 TYR B CA  1 
ATOM   6198 C  C   . TYR C 1 212 ? -36.892 -11.679 -10.39  1   49.18  ? 382 TYR B C   1 
ATOM   6199 O  O   . TYR C 1 212 ? -36.218 -12.422 -11.111 1   50.46  ? 382 TYR B O   1 
ATOM   6200 C  CB  . TYR C 1 212 ? -35.477 -10.529 -8.764  1   41.17  ? 382 TYR B CB  1 
ATOM   6201 C  CG  . TYR C 1 212 ? -34.89  -10.308 -7.376  1   40.78  ? 382 TYR B CG  1 
ATOM   6202 C  CD1 . TYR C 1 212 ? -35.658 -10.433 -6.211  1   40.2   ? 382 TYR B CD1 1 
ATOM   6203 C  CD2 . TYR C 1 212 ? -33.552 -9.947  -7.243  1   37.48  ? 382 TYR B CD2 1 
ATOM   6204 C  CE1 . TYR C 1 212 ? -35.103 -10.2   -4.964  1   37.73  ? 382 TYR B CE1 1 
ATOM   6205 C  CE2 . TYR C 1 212 ? -32.988 -9.716  -6.004  1   37.03  ? 382 TYR B CE2 1 
ATOM   6206 C  CZ  . TYR C 1 212 ? -33.765 -9.843  -4.867  1   39.11  ? 382 TYR B CZ  1 
ATOM   6207 O  OH  . TYR C 1 212 ? -33.167 -9.607  -3.662  1   41.04  ? 382 TYR B OH  1 
ATOM   6208 N  N   . THR C 1 213 ? -37.902 -10.924 -10.847 1   51.89  ? 383 THR B N   1 
ATOM   6209 C  CA  . THR C 1 213 ? -38.303 -10.82  -12.247 1   53.35  ? 383 THR B CA  1 
ATOM   6210 C  C   . THR C 1 213 ? -38.131 -9.361  -12.651 1   53.78  ? 383 THR B C   1 
ATOM   6211 O  O   . THR C 1 213 ? -37.915 -8.516  -11.781 1   54.36  ? 383 THR B O   1 
ATOM   6212 C  CB  . THR C 1 213 ? -39.776 -11.222 -12.432 1   54.9   ? 383 THR B CB  1 
ATOM   6213 O  OG1 . THR C 1 213 ? -40.549 -10.297 -11.668 1   57.43  ? 383 THR B OG1 1 
ATOM   6214 C  CG2 . THR C 1 213 ? -40.112 -12.631 -11.98  1   51.97  ? 383 THR B CG2 1 
ATOM   6215 N  N   . LEU C 1 214 ? -38.315 -9.061  -13.942 1   55.42  ? 384 LEU B N   1 
ATOM   6216 C  CA  . LEU C 1 214 ? -38.347 -7.669  -14.362 1   58.49  ? 384 LEU B CA  1 
ATOM   6217 C  C   . LEU C 1 214 ? -39.453 -6.889  -13.656 1   61.17  ? 384 LEU B C   1 
ATOM   6218 O  O   . LEU C 1 214 ? -39.307 -5.684  -13.475 1   63.47  ? 384 LEU B O   1 
ATOM   6219 C  CB  . LEU C 1 214 ? -38.453 -7.48   -15.871 1   60.09  ? 384 LEU B CB  1 
ATOM   6220 C  CG  . LEU C 1 214 ? -37.188 -7.8    -16.66  1   60.06  ? 384 LEU B CG  1 
ATOM   6221 C  CD1 . LEU C 1 214 ? -37.418 -7.599  -18.14  1   57.78  ? 384 LEU B CD1 1 
ATOM   6222 C  CD2 . LEU C 1 214 ? -36.044 -6.938  -16.122 1   61.24  ? 384 LEU B CD2 1 
ATOM   6223 N  N   . GLU C 1 215 ? -40.568 -7.547  -13.308 1   64.13  ? 385 GLU B N   1 
ATOM   6224 C  CA  . GLU C 1 215 ? -41.602 -6.868  -12.531 1   66.8   ? 385 GLU B CA  1 
ATOM   6225 C  C   . GLU C 1 215 ? -41.089 -6.418  -11.16  1   60.96  ? 385 GLU B C   1 
ATOM   6226 O  O   . GLU C 1 215 ? -41.406 -5.324  -10.71  1   61.45  ? 385 GLU B O   1 
ATOM   6227 C  CB  . GLU C 1 215 ? -42.867 -7.689  -12.312 1   72.27  ? 385 GLU B CB  1 
ATOM   6228 C  CG  . GLU C 1 215 ? -43.978 -7.349  -13.303 1   91.47  ? 385 GLU B CG  1 
ATOM   6229 C  CD  . GLU C 1 215 ? -45.231 -8.173  -13.038 1   110.22 ? 385 GLU B CD  1 
ATOM   6230 O  OE1 . GLU C 1 215 ? -46.175 -8.154  -13.878 1   116.27 ? 385 GLU B OE1 1 
ATOM   6231 O  OE2 . GLU C 1 215 ? -45.25  -8.84   -11.967 1   109.98 ? 385 GLU B OE2 1 
ATOM   6232 N  N   . THR C 1 216 ? -40.326 -7.269  -10.477 1   55     ? 386 THR B N   1 
ATOM   6233 C  CA  . THR C 1 216 ? -39.959 -6.945  -9.116  1   54.42  ? 386 THR B CA  1 
ATOM   6234 C  C   . THR C 1 216 ? -38.861 -5.878  -9.148  1   56.74  ? 386 THR B C   1 
ATOM   6235 O  O   . THR C 1 216 ? -38.859 -4.99   -8.297  1   58.33  ? 386 THR B O   1 
ATOM   6236 C  CB  . THR C 1 216 ? -39.662 -8.185  -8.257  1   52.36  ? 386 THR B CB  1 
ATOM   6237 O  OG1 . THR C 1 216 ? -38.444 -8.836  -8.609  1   51.7   ? 386 THR B OG1 1 
ATOM   6238 C  CG2 . THR C 1 216 ? -40.804 -9.185  -8.266  1   51.86  ? 386 THR B CG2 1 
ATOM   6239 N  N   . LEU C 1 217 ? -37.99  -5.906  -10.174 1   51.71  ? 387 LEU B N   1 
ATOM   6240 C  CA  . LEU C 1 217 ? -36.898 -4.949  -10.273 1   46.89  ? 387 LEU B CA  1 
ATOM   6241 C  C   . LEU C 1 217 ? -37.344 -3.601  -10.846 1   50.08  ? 387 LEU B C   1 
ATOM   6242 O  O   . LEU C 1 217 ? -36.6   -2.635  -10.751 1   49.74  ? 387 LEU B O   1 
ATOM   6243 C  CB  . LEU C 1 217 ? -35.832 -5.563  -11.168 1   44.66  ? 387 LEU B CB  1 
ATOM   6244 C  CG  . LEU C 1 217 ? -35.267 -6.913  -10.728 1   42.21  ? 387 LEU B CG  1 
ATOM   6245 C  CD1 . LEU C 1 217 ? -34.299 -7.378  -11.81  1   41.18  ? 387 LEU B CD1 1 
ATOM   6246 C  CD2 . LEU C 1 217 ? -34.602 -6.829  -9.352  1   38.28  ? 387 LEU B CD2 1 
ATOM   6247 N  N   . LYS C 1 218 ? -38.545 -3.516  -11.433 1   51.3   ? 388 LYS B N   1 
ATOM   6248 C  CA  . LYS C 1 218 ? -38.967 -2.339  -12.179 1   53.41  ? 388 LYS B CA  1 
ATOM   6249 C  C   . LYS C 1 218 ? -38.728 -1.031  -11.409 1   55.54  ? 388 LYS B C   1 
ATOM   6250 O  O   . LYS C 1 218 ? -38.112 -0.103  -11.938 1   55.95  ? 388 LYS B O   1 
ATOM   6251 C  CB  . LYS C 1 218 ? -40.428 -2.466  -12.635 1   53.46  ? 388 LYS B CB  1 
ATOM   6252 C  CG  . LYS C 1 218 ? -40.826 -1.547  -13.781 1   53.84  ? 388 LYS B CG  1 
ATOM   6253 C  CD  . LYS C 1 218 ? -42.313 -1.257  -13.904 1   58.91  ? 388 LYS B CD  1 
ATOM   6254 C  CE  . LYS C 1 218 ? -42.629 -0.399  -15.098 1   63.45  ? 388 LYS B CE  1 
ATOM   6255 N  NZ  . LYS C 1 218 ? -44.062 -0.127  -15.208 1   62.74  ? 388 LYS B NZ  1 
ATOM   6256 N  N   . PRO C 1 219 ? -39.254 -0.845  -10.174 1   55.69  ? 389 PRO B N   1 
ATOM   6257 C  CA  . PRO C 1 219 ? -38.989 0.398   -9.439  1   55.61  ? 389 PRO B CA  1 
ATOM   6258 C  C   . PRO C 1 219 ? -37.512 0.829   -9.411  1   55.67  ? 389 PRO B C   1 
ATOM   6259 O  O   . PRO C 1 219 ? -37.165 1.919   -9.859  1   59.55  ? 389 PRO B O   1 
ATOM   6260 C  CB  . PRO C 1 219 ? -39.593 0.133   -8.049  1   52.92  ? 389 PRO B CB  1 
ATOM   6261 C  CG  . PRO C 1 219 ? -40.641 -0.948  -8.282  1   51.72  ? 389 PRO B CG  1 
ATOM   6262 C  CD  . PRO C 1 219 ? -40.127 -1.781  -9.444  1   53.46  ? 389 PRO B CD  1 
ATOM   6263 N  N   . CYS C 1 220 ? -36.623 -0.044  -8.934  1   55.39  ? 390 CYS B N   1 
ATOM   6264 C  CA  . CYS C 1 220 ? -35.184 0.227   -8.876  1   53.83  ? 390 CYS B CA  1 
ATOM   6265 C  C   . CYS C 1 220 ? -34.609 0.534   -10.264 1   52.71  ? 390 CYS B C   1 
ATOM   6266 O  O   . CYS C 1 220 ? -33.753 1.401   -10.451 1   52.95  ? 390 CYS B O   1 
ATOM   6267 C  CB  . CYS C 1 220 ? -34.448 -0.963  -8.268  1   48.12  ? 390 CYS B CB  1 
ATOM   6268 S  SG  . CYS C 1 220 ? -32.667 -0.715  -8.105  1   51.73  ? 390 CYS B SG  1 
ATOM   6269 N  N   . LEU C 1 221 ? -35.08  -0.227  -11.243 1   51.59  ? 391 LEU B N   1 
ATOM   6270 C  CA  . LEU C 1 221 ? -34.645 -0.117  -12.62  1   53.7   ? 391 LEU B CA  1 
ATOM   6271 C  C   . LEU C 1 221 ? -34.999 1.253   -13.216 1   54.03  ? 391 LEU B C   1 
ATOM   6272 O  O   . LEU C 1 221 ? -34.165 1.858   -13.885 1   53.63  ? 391 LEU B O   1 
ATOM   6273 C  CB  . LEU C 1 221 ? -35.364 -1.28   -13.302 1   58.59  ? 391 LEU B CB  1 
ATOM   6274 C  CG  . LEU C 1 221 ? -34.756 -1.835  -14.59  1   63.39  ? 391 LEU B CG  1 
ATOM   6275 C  CD1 . LEU C 1 221 ? -33.225 -1.789  -14.555 1   60.82  ? 391 LEU B CD1 1 
ATOM   6276 C  CD2 . LEU C 1 221 ? -35.271 -3.285  -14.683 1   63.35  ? 391 LEU B CD2 1 
ATOM   6277 N  N   . LEU C 1 222 ? -36.223 1.749   -12.983 1   52.2   ? 392 LEU B N   1 
ATOM   6278 C  CA  . LEU C 1 222 ? -36.602 3.086   -13.414 1   53.28  ? 392 LEU B CA  1 
ATOM   6279 C  C   . LEU C 1 222 ? -35.689 4.134   -12.782 1   53.66  ? 392 LEU B C   1 
ATOM   6280 O  O   . LEU C 1 222 ? -35.18  5.018   -13.457 1   55.16  ? 392 LEU B O   1 
ATOM   6281 C  CB  . LEU C 1 222 ? -38.059 3.347   -13.055 1   54.97  ? 392 LEU B CB  1 
ATOM   6282 C  CG  . LEU C 1 222 ? -39.112 2.655   -13.929 1   58.15  ? 392 LEU B CG  1 
ATOM   6283 C  CD1 . LEU C 1 222 ? -40.51  3.21    -13.588 1   61.29  ? 392 LEU B CD1 1 
ATOM   6284 C  CD2 . LEU C 1 222 ? -38.87  2.731   -15.43  1   54.62  ? 392 LEU B CD2 1 
ATOM   6285 N  N   . ASP C 1 223 ? -35.479 4.026   -11.472 1   53.54  ? 393 ASP B N   1 
ATOM   6286 C  CA  . ASP C 1 223 ? -34.532 4.887   -10.784 1   55.75  ? 393 ASP B CA  1 
ATOM   6287 C  C   . ASP C 1 223 ? -33.116 4.814   -11.38  1   55.43  ? 393 ASP B C   1 
ATOM   6288 O  O   . ASP C 1 223 ? -32.52  5.857   -11.628 1   55.06  ? 393 ASP B O   1 
ATOM   6289 C  CB  . ASP C 1 223 ? -34.473 4.576   -9.3    1   57     ? 393 ASP B CB  1 
ATOM   6290 C  CG  . ASP C 1 223 ? -35.596 5.145   -8.457  1   57.87  ? 393 ASP B CG  1 
ATOM   6291 O  OD1 . ASP C 1 223 ? -36.052 6.256   -8.761  1   57.38  ? 393 ASP B OD1 1 
ATOM   6292 O  OD2 . ASP C 1 223 ? -35.965 4.468   -7.484  1   63.75  ? 393 ASP B OD2 1 
ATOM   6293 N  N   . LEU C 1 224 ? -32.552 3.601   -11.558 1   52.64  ? 394 LEU B N   1 
ATOM   6294 C  CA  . LEU C 1 224 ? -31.178 3.438   -12.034 1   52.19  ? 394 LEU B CA  1 
ATOM   6295 C  C   . LEU C 1 224 ? -31.006 3.976   -13.458 1   55.73  ? 394 LEU B C   1 
ATOM   6296 O  O   . LEU C 1 224 ? -29.979 4.558   -13.791 1   56     ? 394 LEU B O   1 
ATOM   6297 C  CB  . LEU C 1 224 ? -30.75  1.977   -11.982 1   46.49  ? 394 LEU B CB  1 
ATOM   6298 C  CG  . LEU C 1 224 ? -29.239 1.747   -11.932 1   44.04  ? 394 LEU B CG  1 
ATOM   6299 C  CD1 . LEU C 1 224 ? -28.584 2.404   -10.728 1   43.51  ? 394 LEU B CD1 1 
ATOM   6300 C  CD2 . LEU C 1 224 ? -28.927 0.267   -11.887 1   42.93  ? 394 LEU B CD2 1 
ATOM   6301 N  N   . HIS C 1 225 ? -32.02  3.784   -14.294 1   54.65  ? 395 HIS B N   1 
ATOM   6302 C  CA  . HIS C 1 225 ? -31.958 4.235   -15.708 1   55.37  ? 395 HIS B CA  1 
ATOM   6303 C  C   . HIS C 1 225 ? -31.893 5.762   -15.766 1   59.25  ? 395 HIS B C   1 
ATOM   6304 O  O   . HIS C 1 225 ? -31.167 6.312   -16.609 1   60.39  ? 395 HIS B O   1 
ATOM   6305 C  CB  . HIS C 1 225 ? -33.16  3.655   -16.453 1   51.35  ? 395 HIS B CB  1 
ATOM   6306 C  CG  . HIS C 1 225 ? -33.352 4.115   -17.85  1   52.8   ? 395 HIS B CG  1 
ATOM   6307 N  ND1 . HIS C 1 225 ? -32.44  3.872   -18.849 1   54.2   ? 395 HIS B ND1 1 
ATOM   6308 C  CD2 . HIS C 1 225 ? -34.363 4.772   -18.418 1   54.72  ? 395 HIS B CD2 1 
ATOM   6309 C  CE1 . HIS C 1 225 ? -32.897 4.382   -19.978 1   55.06  ? 395 HIS B CE1 1 
ATOM   6310 N  NE2 . HIS C 1 225 ? -34.061 4.934   -19.74  1   54.85  ? 395 HIS B NE2 1 
ATOM   6311 N  N   . GLN C 1 226 ? -32.638 6.428   -14.892 1   56.94  ? 396 GLN B N   1 
ATOM   6312 C  CA  . GLN C 1 226 ? -32.634 7.905   -14.843 1   56.03  ? 396 GLN B CA  1 
ATOM   6313 C  C   . GLN C 1 226 ? -31.259 8.374   -14.377 1   58.19  ? 396 GLN B C   1 
ATOM   6314 O  O   . GLN C 1 226 ? -30.732 9.331   -14.959 1   63.37  ? 396 GLN B O   1 
ATOM   6315 C  CB  . GLN C 1 226 ? -33.719 8.335   -13.863 1   53.6   ? 396 GLN B CB  1 
ATOM   6316 C  CG  . GLN C 1 226 ? -33.972 9.836   -13.777 1   55.87  ? 396 GLN B CG  1 
ATOM   6317 C  CD  . GLN C 1 226 ? -35.16  10.226  -12.927 1   54.61  ? 396 GLN B CD  1 
ATOM   6318 O  OE1 . GLN C 1 226 ? -35.904 9.37    -12.435 1   54.89  ? 396 GLN B OE1 1 
ATOM   6319 N  NE2 . GLN C 1 226 ? -35.375 11.524  -12.772 1   51.96  ? 396 GLN B NE2 1 
ATOM   6320 N  N   . THR C 1 227 ? -30.709 7.716   -13.363 1   55.02  ? 397 THR B N   1 
ATOM   6321 C  CA  . THR C 1 227 ? -29.394 8.097   -12.828 1   51.96  ? 397 THR B CA  1 
ATOM   6322 C  C   . THR C 1 227 ? -28.375 7.97    -13.931 1   51.56  ? 397 THR B C   1 
ATOM   6323 O  O   . THR C 1 227 ? -27.59  8.906   -14.111 1   56.9   ? 397 THR B O   1 
ATOM   6324 C  CB  . THR C 1 227 ? -29.092 7.21    -11.625 1   49.21  ? 397 THR B CB  1 
ATOM   6325 O  OG1 . THR C 1 227 ? -29.995 7.64    -10.613 1   48.46  ? 397 THR B OG1 1 
ATOM   6326 C  CG2 . THR C 1 227 ? -27.666 7.346   -11.127 1   47.25  ? 397 THR B CG2 1 
ATOM   6327 N  N   . TYR C 1 228 ? -28.394 6.857   -14.657 1   50.82  ? 398 TYR B N   1 
ATOM   6328 C  CA  . TYR C 1 228 ? -27.493 6.684   -15.791 1   51.59  ? 398 TYR B CA  1 
ATOM   6329 C  C   . TYR C 1 228 ? -27.649 7.793   -16.843 1   57.53  ? 398 TYR B C   1 
ATOM   6330 O  O   . TYR C 1 228 ? -26.636 8.269   -17.371 1   59.56  ? 398 TYR B O   1 
ATOM   6331 C  CB  . TYR C 1 228 ? -27.816 5.333   -16.422 1   48.58  ? 398 TYR B CB  1 
ATOM   6332 C  CG  . TYR C 1 228 ? -26.829 4.818   -17.45  1   49.6   ? 398 TYR B CG  1 
ATOM   6333 C  CD1 . TYR C 1 228 ? -25.565 5.37    -17.603 1   50.31  ? 398 TYR B CD1 1 
ATOM   6334 C  CD2 . TYR C 1 228 ? -27.146 3.704   -18.21  1   51.95  ? 398 TYR B CD2 1 
ATOM   6335 C  CE1 . TYR C 1 228 ? -24.656 4.828   -18.498 1   53.73  ? 398 TYR B CE1 1 
ATOM   6336 C  CE2 . TYR C 1 228 ? -26.244 3.157   -19.105 1   53.6   ? 398 TYR B CE2 1 
ATOM   6337 C  CZ  . TYR C 1 228 ? -24.991 3.72    -19.257 1   55.21  ? 398 TYR B CZ  1 
ATOM   6338 O  OH  . TYR C 1 228 ? -24.115 3.17    -20.161 1   59.51  ? 398 TYR B OH  1 
ATOM   6339 N  N   . LEU C 1 229 ? -28.903 8.183   -17.17  1   56.35  ? 399 LEU B N   1 
ATOM   6340 C  CA  . LEU C 1 229 ? -29.166 9.264   -18.107 1   56.85  ? 399 LEU B CA  1 
ATOM   6341 C  C   . LEU C 1 229 ? -28.65  10.581  -17.522 1   59.03  ? 399 LEU B C   1 
ATOM   6342 O  O   . LEU C 1 229 ? -28.138 11.412  -18.262 1   60.96  ? 399 LEU B O   1 
ATOM   6343 C  CB  . LEU C 1 229 ? -30.648 9.4     -18.477 1   58.5   ? 399 LEU B CB  1 
ATOM   6344 C  CG  . LEU C 1 229 ? -31.285 8.429   -19.486 1   57.49  ? 399 LEU B CG  1 
ATOM   6345 C  CD1 . LEU C 1 229 ? -32.785 8.343   -19.261 1   56.74  ? 399 LEU B CD1 1 
ATOM   6346 C  CD2 . LEU C 1 229 ? -31.084 8.81    -20.932 1   57.26  ? 399 LEU B CD2 1 
ATOM   6347 N  N   . ARG C 1 230 ? -28.794 10.796  -16.205 1   59.76  ? 400 ARG B N   1 
ATOM   6348 C  CA  . ARG C 1 230 ? -28.482 12.101  -15.618 1   65.43  ? 400 ARG B CA  1 
ATOM   6349 C  C   . ARG C 1 230 ? -26.987 12.277  -15.309 1   63.87  ? 400 ARG B C   1 
ATOM   6350 O  O   . ARG C 1 230 ? -26.564 13.368  -14.912 1   63.35  ? 400 ARG B O   1 
ATOM   6351 C  CB  . ARG C 1 230 ? -29.384 12.362  -14.402 1   67.42  ? 400 ARG B CB  1 
ATOM   6352 C  CG  . ARG C 1 230 ? -30.752 12.931  -14.772 1   76.43  ? 400 ARG B CG  1 
ATOM   6353 C  CD  . ARG C 1 230 ? -31.877 12.584  -13.809 1   85.41  ? 400 ARG B CD  1 
ATOM   6354 N  NE  . ARG C 1 230 ? -32.973 13.562  -13.738 1   104.84 ? 400 ARG B NE  1 
ATOM   6355 C  CZ  . ARG C 1 230 ? -34.236 13.45   -14.18  1   103.77 ? 400 ARG B CZ  1 
ATOM   6356 N  NH1 . ARG C 1 230 ? -34.61  12.446  -14.958 1   106.81 ? 400 ARG B NH1 1 
ATOM   6357 N  NH2 . ARG C 1 230 ? -35.118 14.387  -13.875 1   94.44  ? 400 ARG B NH2 1 
ATOM   6358 N  N   . ALA C 1 231 ? -26.18  11.228  -15.542 1   57.42  ? 401 ALA B N   1 
ATOM   6359 C  CA  . ALA C 1 231 ? -24.913 11.082  -14.839 1   54.74  ? 401 ALA B CA  1 
ATOM   6360 C  C   . ALA C 1 231 ? -23.886 12.117  -15.292 1   57.14  ? 401 ALA B C   1 
ATOM   6361 O  O   . ALA C 1 231 ? -23.098 12.592  -14.468 1   58.87  ? 401 ALA B O   1 
ATOM   6362 C  CB  . ALA C 1 231 ? -24.385 9.673   -14.955 1   49.66  ? 401 ALA B CB  1 
ATOM   6363 N  N   . PRO C 1 232 ? -23.788 12.443  -16.605 1   57.1   ? 402 PRO B N   1 
ATOM   6364 C  CA  . PRO C 1 232 ? -22.94  13.547  -17.04  1   58.05  ? 402 PRO B CA  1 
ATOM   6365 C  C   . PRO C 1 232 ? -23.273 14.858  -16.333 1   60.75  ? 402 PRO B C   1 
ATOM   6366 O  O   . PRO C 1 232 ? -22.404 15.714  -16.182 1   62.3   ? 402 PRO B O   1 
ATOM   6367 C  CB  . PRO C 1 232 ? -23.244 13.596  -18.54  1   57.91  ? 402 PRO B CB  1 
ATOM   6368 C  CG  . PRO C 1 232 ? -23.58  12.178  -18.932 1   55.36  ? 402 PRO B CG  1 
ATOM   6369 C  CD  . PRO C 1 232 ? -24.369 11.706  -17.739 1   56.42  ? 402 PRO B CD  1 
ATOM   6370 N  N   . GLN C 1 233 ? -24.528 14.999  -15.894 1   61.84  ? 403 GLN B N   1 
ATOM   6371 C  CA  . GLN C 1 233 ? -25.025 16.245  -15.328 1   66.17  ? 403 GLN B CA  1 
ATOM   6372 C  C   . GLN C 1 233 ? -24.795 16.334  -13.814 1   64.53  ? 403 GLN B C   1 
ATOM   6373 O  O   . GLN C 1 233 ? -24.74  17.456  -13.301 1   65.27  ? 403 GLN B O   1 
ATOM   6374 C  CB  . GLN C 1 233 ? -26.521 16.415  -15.62  1   71.85  ? 403 GLN B CB  1 
ATOM   6375 C  CG  . GLN C 1 233 ? -26.831 17.239  -16.861 1   77.45  ? 403 GLN B CG  1 
ATOM   6376 C  CD  . GLN C 1 233 ? -26.089 16.764  -18.091 1   84.25  ? 403 GLN B CD  1 
ATOM   6377 O  OE1 . GLN C 1 233 ? -25.21  17.458  -18.62  1   87.94  ? 403 GLN B OE1 1 
ATOM   6378 N  NE2 . GLN C 1 233 ? -26.423 15.56   -18.542 1   85.35  ? 403 GLN B NE2 1 
ATOM   6379 N  N   . HIS C 1 234 ? -24.685 15.178  -13.112 1   58.2   ? 404 HIS B N   1 
ATOM   6380 C  CA  . HIS C 1 234 ? -24.587 15.113  -11.654 1   56.15  ? 404 HIS B CA  1 
ATOM   6381 C  C   . HIS C 1 234 ? -23.444 15.995  -11.141 1   56.77  ? 404 HIS B C   1 
ATOM   6382 O  O   . HIS C 1 234 ? -22.441 16.186  -11.822 1   58.09  ? 404 HIS B O   1 
ATOM   6383 C  CB  . HIS C 1 234 ? -24.359 13.663  -11.218 1   53.58  ? 404 HIS B CB  1 
ATOM   6384 C  CG  . HIS C 1 234 ? -24.743 13.32   -9.813  1   54.09  ? 404 HIS B CG  1 
ATOM   6385 N  ND1 . HIS C 1 234 ? -24.08  13.776  -8.69   1   55.01  ? 404 HIS B ND1 1 
ATOM   6386 C  CD2 . HIS C 1 234 ? -25.73  12.518  -9.356  1   52.29  ? 404 HIS B CD2 1 
ATOM   6387 C  CE1 . HIS C 1 234 ? -24.663 13.276  -7.601  1   53.53  ? 404 HIS B CE1 1 
ATOM   6388 N  NE2 . HIS C 1 234 ? -25.669 12.512  -7.98   1   51.41  ? 404 HIS B NE2 1 
ATOM   6389 N  N   . ALA C 1 235 ? -23.589 16.533  -9.931  1   57.01  ? 405 ALA B N   1 
ATOM   6390 C  CA  . ALA C 1 235 ? -22.532 17.331  -9.304  1   59.36  ? 405 ALA B CA  1 
ATOM   6391 C  C   . ALA C 1 235 ? -21.287 16.5    -8.98   1   58.43  ? 405 ALA B C   1 
ATOM   6392 O  O   . ALA C 1 235 ? -20.198 17.05   -8.915  1   60.01  ? 405 ALA B O   1 
ATOM   6393 C  CB  . ALA C 1 235 ? -23.053 17.973  -8.034  1   57.37  ? 405 ALA B CB  1 
ATOM   6394 N  N   . GLN C 1 236 ? -21.458 15.189  -8.748  1   55.64  ? 406 GLN B N   1 
ATOM   6395 C  CA  . GLN C 1 236 ? -20.359 14.272  -8.466  1   56.06  ? 406 GLN B CA  1 
ATOM   6396 C  C   . GLN C 1 236 ? -19.946 13.503  -9.722  1   54.95  ? 406 GLN B C   1 
ATOM   6397 O  O   . GLN C 1 236 ? -20.794 12.909  -10.372 1   58.71  ? 406 GLN B O   1 
ATOM   6398 C  CB  . GLN C 1 236 ? -20.82  13.318  -7.364  1   54.89  ? 406 GLN B CB  1 
ATOM   6399 C  CG  . GLN C 1 236 ? -20.601 13.849  -5.948  1   59.19  ? 406 GLN B CG  1 
ATOM   6400 C  CD  . GLN C 1 236 ? -21.327 15.138  -5.629  1   65.09  ? 406 GLN B CD  1 
ATOM   6401 O  OE1 . GLN C 1 236 ? -22.555 15.214  -5.711  1   71.14  ? 406 GLN B OE1 1 
ATOM   6402 N  NE2 . GLN C 1 236 ? -20.582 16.153  -5.216  1   66.73  ? 406 GLN B NE2 1 
ATOM   6403 N  N   . GLN C 1 237 ? -18.644 13.48   -10.042 1   53.36  ? 407 GLN B N   1 
ATOM   6404 C  CA  . GLN C 1 237 ? -18.168 12.983  -11.326 1   51.64  ? 407 GLN B CA  1 
ATOM   6405 C  C   . GLN C 1 237 ? -17.042 11.958  -11.177 1   51.6   ? 407 GLN B C   1 
ATOM   6406 O  O   . GLN C 1 237 ? -16.597 11.372  -12.17  1   51.51  ? 407 GLN B O   1 
ATOM   6407 C  CB  . GLN C 1 237 ? -17.745 14.156  -12.206 1   52.08  ? 407 GLN B CB  1 
ATOM   6408 C  CG  . GLN C 1 237 ? -18.898 14.964  -12.799 1   55.34  ? 407 GLN B CG  1 
ATOM   6409 C  CD  . GLN C 1 237 ? -19.802 14.172  -13.731 1   57.96  ? 407 GLN B CD  1 
ATOM   6410 O  OE1 . GLN C 1 237 ? -19.338 13.402  -14.575 1   61.77  ? 407 GLN B OE1 1 
ATOM   6411 N  NE2 . GLN C 1 237 ? -21.113 14.312  -13.586 1   56.34  ? 407 GLN B NE2 1 
ATOM   6412 N  N   . SER C 1 238 ? -16.624 11.693  -9.935  1   50.55  ? 408 SER B N   1 
ATOM   6413 C  CA  . SER C 1 238 ? -15.461 10.85   -9.7    1   50.37  ? 408 SER B CA  1 
ATOM   6414 C  C   . SER C 1 238 ? -15.676 9.439   -10.24  1   47.28  ? 408 SER B C   1 
ATOM   6415 O  O   . SER C 1 238 ? -14.765 8.829   -10.771 1   47.63  ? 408 SER B O   1 
ATOM   6416 C  CB  . SER C 1 238 ? -15.107 10.834  -8.246  1   51.21  ? 408 SER B CB  1 
ATOM   6417 O  OG  . SER C 1 238 ? -14.717 12.152  -7.877  1   56.83  ? 408 SER B OG  1 
ATOM   6418 N  N   . ILE C 1 239 ? -16.886 8.917   -10.105 1   45.72  ? 409 ILE B N   1 
ATOM   6419 C  CA  . ILE C 1 239 ? -17.17  7.586   -10.62  1   45.54  ? 409 ILE B CA  1 
ATOM   6420 C  C   . ILE C 1 239 ? -17.092 7.571   -12.154 1   47.38  ? 409 ILE B C   1 
ATOM   6421 O  O   . ILE C 1 239 ? -16.533 6.627   -12.712 1   50.37  ? 409 ILE B O   1 
ATOM   6422 C  CB  . ILE C 1 239 ? -18.488 6.994   -10.061 1   43.01  ? 409 ILE B CB  1 
ATOM   6423 C  CG1 . ILE C 1 239 ? -18.432 6.72    -8.564  1   39.82  ? 409 ILE B CG1 1 
ATOM   6424 C  CG2 . ILE C 1 239 ? -18.893 5.744   -10.836 1   41.62  ? 409 ILE B CG2 1 
ATOM   6425 C  CD1 . ILE C 1 239 ? -19.776 6.494   -7.907  1   39.14  ? 409 ILE B CD1 1 
ATOM   6426 N  N   . ARG C 1 240 ? -17.608 8.597   -12.843 1   46.23  ? 410 ARG B N   1 
ATOM   6427 C  CA  . ARG C 1 240 ? -17.512 8.576   -14.294 1   49.7   ? 410 ARG B CA  1 
ATOM   6428 C  C   . ARG C 1 240 ? -16.051 8.664   -14.747 1   54.67  ? 410 ARG B C   1 
ATOM   6429 O  O   . ARG C 1 240 ? -15.628 7.91    -15.647 1   56.13  ? 410 ARG B O   1 
ATOM   6430 C  CB  . ARG C 1 240 ? -18.353 9.65    -14.988 1   52.44  ? 410 ARG B CB  1 
ATOM   6431 C  CG  . ARG C 1 240 ? -19.862 9.438   -14.966 1   53.18  ? 410 ARG B CG  1 
ATOM   6432 C  CD  . ARG C 1 240 ? -20.515 9.828   -16.286 1   54.44  ? 410 ARG B CD  1 
ATOM   6433 N  NE  . ARG C 1 240 ? -20.225 11.235  -16.556 1   55.51  ? 410 ARG B NE  1 
ATOM   6434 C  CZ  . ARG C 1 240 ? -19.899 11.743  -17.732 1   54.59  ? 410 ARG B CZ  1 
ATOM   6435 N  NH1 . ARG C 1 240 ? -20.104 11.093  -18.855 1   55.65  ? 410 ARG B NH1 1 
ATOM   6436 N  NH2 . ARG C 1 240 ? -19.416 12.951  -17.792 1   55     ? 410 ARG B NH2 1 
ATOM   6437 N  N   . GLU C 1 241 ? -15.291 9.601   -14.148 1   56.24  ? 411 GLU B N   1 
ATOM   6438 C  CA  . GLU C 1 241 ? -13.873 9.76    -14.466 1   58.34  ? 411 GLU B CA  1 
ATOM   6439 C  C   . GLU C 1 241 ? -13.19  8.404   -14.303 1   57.97  ? 411 GLU B C   1 
ATOM   6440 O  O   . GLU C 1 241 ? -12.484 7.961   -15.201 1   64.27  ? 411 GLU B O   1 
ATOM   6441 C  CB  . GLU C 1 241 ? -13.107 10.73   -13.566 1   60.69  ? 411 GLU B CB  1 
ATOM   6442 C  CG  . GLU C 1 241 ? -13.662 12.148  -13.556 1   67.63  ? 411 GLU B CG  1 
ATOM   6443 C  CD  . GLU C 1 241 ? -13.491 12.931  -14.843 1   82.17  ? 411 GLU B CD  1 
ATOM   6444 O  OE1 . GLU C 1 241 ? -12.651 12.593  -15.724 1   82.77  ? 411 GLU B OE1 1 
ATOM   6445 O  OE2 . GLU C 1 241 ? -14.259 13.915  -14.941 1   89.58  ? 411 GLU B OE2 1 
ATOM   6446 N  N   . LYS C 1 242 ? -13.435 7.747   -13.164 1   51.87  ? 412 LYS B N   1 
ATOM   6447 C  CA  . LYS C 1 242 ? -12.866 6.452   -12.852 1   49.51  ? 412 LYS B CA  1 
ATOM   6448 C  C   . LYS C 1 242 ? -13.175 5.456   -13.96  1   51.33  ? 412 LYS B C   1 
ATOM   6449 O  O   . LYS C 1 242 ? -12.273 4.759   -14.438 1   53.24  ? 412 LYS B O   1 
ATOM   6450 C  CB  . LYS C 1 242 ? -13.441 5.936   -11.534 1   47     ? 412 LYS B CB  1 
ATOM   6451 C  CG  . LYS C 1 242 ? -12.981 4.551   -11.099 1   45.08  ? 412 LYS B CG  1 
ATOM   6452 C  CD  . LYS C 1 242 ? -13.39  4.223   -9.657  1   43.84  ? 412 LYS B CD  1 
ATOM   6453 C  CE  . LYS C 1 242 ? -13.365 2.786   -9.272  1   38.31  ? 412 LYS B CE  1 
ATOM   6454 N  NZ  . LYS C 1 242 ? -14.133 2.534   -8.062  1   37.14  ? 412 LYS B NZ  1 
ATOM   6455 N  N   . TYR C 1 243 ? -14.452 5.38    -14.348 1   50.11  ? 413 TYR B N   1 
ATOM   6456 C  CA  . TYR C 1 243 ? -14.856 4.39    -15.336 1   50.63  ? 413 TYR B CA  1 
ATOM   6457 C  C   . TYR C 1 243 ? -14.589 4.849   -16.78  1   51.85  ? 413 TYR B C   1 
ATOM   6458 O  O   . TYR C 1 243 ? -15.034 4.191   -17.709 1   50.91  ? 413 TYR B O   1 
ATOM   6459 C  CB  . TYR C 1 243 ? -16.267 3.875   -15.052 1   48.17  ? 413 TYR B CB  1 
ATOM   6460 C  CG  . TYR C 1 243 ? -16.338 2.861   -13.922 1   48.07  ? 413 TYR B CG  1 
ATOM   6461 C  CD1 . TYR C 1 243 ? -16.297 3.265   -12.589 1   49.78  ? 413 TYR B CD1 1 
ATOM   6462 C  CD2 . TYR C 1 243 ? -16.465 1.505   -14.191 1   45.83  ? 413 TYR B CD2 1 
ATOM   6463 C  CE1 . TYR C 1 243 ? -16.369 2.345   -11.551 1   50.36  ? 413 TYR B CE1 1 
ATOM   6464 C  CE2 . TYR C 1 243 ? -16.535 0.576   -13.168 1   46.23  ? 413 TYR B CE2 1 
ATOM   6465 C  CZ  . TYR C 1 243 ? -16.464 0.987   -11.843 1   51.52  ? 413 TYR B CZ  1 
ATOM   6466 O  OH  . TYR C 1 243 ? -16.513 0.044   -10.832 1   48.41  ? 413 TYR B OH  1 
ATOM   6467 N  N   . LYS C 1 244 ? -13.801 5.91    -16.995 1   52.7   ? 414 LYS B N   1 
ATOM   6468 C  CA  . LYS C 1 244 ? -13.241 6.168   -18.32  1   53.86  ? 414 LYS B CA  1 
ATOM   6469 C  C   . LYS C 1 244 ? -11.987 5.327   -18.538 1   55.32  ? 414 LYS B C   1 
ATOM   6470 O  O   . LYS C 1 244 ? -11.503 5.177   -19.664 1   57.61  ? 414 LYS B O   1 
ATOM   6471 C  CB  . LYS C 1 244 ? -12.855 7.634   -18.554 1   53.39  ? 414 LYS B CB  1 
ATOM   6472 C  CG  . LYS C 1 244 ? -14.031 8.573   -18.641 1   54.1   ? 414 LYS B CG  1 
ATOM   6473 C  CD  . LYS C 1 244 ? -13.625 10.029  -18.753 1   57.38  ? 414 LYS B CD  1 
ATOM   6474 C  CE  . LYS C 1 244 ? -14.776 10.904  -18.299 1   60.81  ? 414 LYS B CE  1 
ATOM   6475 N  NZ  . LYS C 1 244 ? -14.405 12.321  -18.372 1   67.2   ? 414 LYS B NZ  1 
ATOM   6476 N  N   . ASN C 1 245 ? -11.438 4.818   -17.433 1   55.88  ? 415 ASN B N   1 
ATOM   6477 C  CA  . ASN C 1 245 ? -10.179 4.095   -17.453 1   58.2   ? 415 ASN B CA  1 
ATOM   6478 C  C   . ASN C 1 245 ? -10.349 2.725   -18.114 1   59.49  ? 415 ASN B C   1 
ATOM   6479 O  O   . ASN C 1 245 ? -11.323 2.006   -17.87  1   58.09  ? 415 ASN B O   1 
ATOM   6480 C  CB  . ASN C 1 245 ? -9.591  4.053   -16.049 1   61.37  ? 415 ASN B CB  1 
ATOM   6481 C  CG  . ASN C 1 245 ? -8.145  3.618   -16.033 1   68.31  ? 415 ASN B CG  1 
ATOM   6482 O  OD1 . ASN C 1 245 ? -7.827  2.439   -16.251 1   72.14  ? 415 ASN B OD1 1 
ATOM   6483 N  ND2 . ASN C 1 245 ? -7.258  4.568   -15.763 1   70.99  ? 415 ASN B ND2 1 
ATOM   6484 N  N   . SER C 1 246 ? -9.339  2.351   -18.906 1   64.75  ? 416 SER B N   1 
ATOM   6485 C  CA  . SER C 1 246 ? -9.365  1.129   -19.694 1   66.91  ? 416 SER B CA  1 
ATOM   6486 C  C   . SER C 1 246 ? -9.396  -0.117  -18.809 1   62.01  ? 416 SER B C   1 
ATOM   6487 O  O   . SER C 1 246 ? -9.853  -1.165  -19.25  1   61.69  ? 416 SER B O   1 
ATOM   6488 C  CB  . SER C 1 246 ? -8.214  1.091   -20.65  1   70.95  ? 416 SER B CB  1 
ATOM   6489 O  OG  . SER C 1 246 ? -7.029  0.931   -19.893 1   82.74  ? 416 SER B OG  1 
ATOM   6490 N  N   . LYS C 1 247 ? -8.916  -0.007  -17.57  1   60.22  ? 417 LYS B N   1 
ATOM   6491 C  CA  . LYS C 1 247 ? -9.091  -1.05   -16.572 1   59.31  ? 417 LYS B CA  1 
ATOM   6492 C  C   . LYS C 1 247 ? -10.556 -1.498  -16.508 1   59.03  ? 417 LYS B C   1 
ATOM   6493 O  O   . LYS C 1 247 ? -10.841 -2.677  -16.293 1   58.63  ? 417 LYS B O   1 
ATOM   6494 C  CB  . LYS C 1 247 ? -8.627  -0.436  -15.246 1   63.03  ? 417 LYS B CB  1 
ATOM   6495 C  CG  . LYS C 1 247 ? -8.73   -1.308  -14.002 1   65.81  ? 417 LYS B CG  1 
ATOM   6496 C  CD  . LYS C 1 247 ? -8.063  -0.573  -12.84  1   79.44  ? 417 LYS B CD  1 
ATOM   6497 C  CE  . LYS C 1 247 ? -7.762  -1.413  -11.634 1   83.14  ? 417 LYS B CE  1 
ATOM   6498 N  NZ  . LYS C 1 247 ? -8.984  -2.107  -11.21  1   80.25  ? 417 LYS B NZ  1 
ATOM   6499 N  N   . TYR C 1 248 ? -11.483 -0.547  -16.711 1   55.79  ? 418 TYR B N   1 
ATOM   6500 C  CA  . TYR C 1 248 ? -12.92  -0.793  -16.657 1   52.25  ? 418 TYR B CA  1 
ATOM   6501 C  C   . TYR C 1 248 ? -13.513 -0.64   -18.054 1   52.49  ? 418 TYR B C   1 
ATOM   6502 O  O   . TYR C 1 248 ? -14.709 -0.394  -18.191 1   52.49  ? 418 TYR B O   1 
ATOM   6503 C  CB  . TYR C 1 248 ? -13.615 0.177   -15.688 1   52.69  ? 418 TYR B CB  1 
ATOM   6504 C  CG  . TYR C 1 248 ? -13.007 0.184   -14.287 1   54.83  ? 418 TYR B CG  1 
ATOM   6505 C  CD1 . TYR C 1 248 ? -13.187 -0.897  -13.433 1   49.62  ? 418 TYR B CD1 1 
ATOM   6506 C  CD2 . TYR C 1 248 ? -12.23  1.254   -13.839 1   56.38  ? 418 TYR B CD2 1 
ATOM   6507 C  CE1 . TYR C 1 248 ? -12.62  -0.911  -12.17  1   50.96  ? 418 TYR B CE1 1 
ATOM   6508 C  CE2 . TYR C 1 248 ? -11.642 1.24    -12.585 1   56.42  ? 418 TYR B CE2 1 
ATOM   6509 C  CZ  . TYR C 1 248 ? -11.835 0.15    -11.743 1   57.43  ? 418 TYR B CZ  1 
ATOM   6510 O  OH  . TYR C 1 248 ? -11.261 0.104   -10.484 1   61.92  ? 418 TYR B OH  1 
ATOM   6511 N  N   . HIS C 1 249 ? -12.665 -0.75   -19.079 1   51.09  ? 419 HIS B N   1 
ATOM   6512 C  CA  . HIS C 1 249 ? -13.122 -0.88   -20.454 1   55.53  ? 419 HIS B CA  1 
ATOM   6513 C  C   . HIS C 1 249 ? -13.837 0.387   -20.921 1   57.21  ? 419 HIS B C   1 
ATOM   6514 O  O   . HIS C 1 249 ? -14.636 0.316   -21.844 1   60.88  ? 419 HIS B O   1 
ATOM   6515 C  CB  . HIS C 1 249 ? -13.968 -2.145  -20.661 1   53.89  ? 419 HIS B CB  1 
ATOM   6516 C  CG  . HIS C 1 249 ? -13.291 -3.385  -20.182 1   58.33  ? 419 HIS B CG  1 
ATOM   6517 N  ND1 . HIS C 1 249 ? -13.525 -3.943  -18.932 1   61.53  ? 419 HIS B ND1 1 
ATOM   6518 C  CD2 . HIS C 1 249 ? -12.369 -4.161  -20.771 1   58.37  ? 419 HIS B CD2 1 
ATOM   6519 C  CE1 . HIS C 1 249 ? -12.762 -5.027  -18.777 1   60.12  ? 419 HIS B CE1 1 
ATOM   6520 N  NE2 . HIS C 1 249 ? -12.049 -5.17   -19.881 1   60.84  ? 419 HIS B NE2 1 
ATOM   6521 N  N   . GLY C 1 250 ? -13.555 1.524   -20.282 1   56.79  ? 420 GLY B N   1 
ATOM   6522 C  CA  . GLY C 1 250 ? -14.135 2.824   -20.678 1   55.62  ? 420 GLY B CA  1 
ATOM   6523 C  C   . GLY C 1 250 ? -15.64  2.797   -20.773 1   54.29  ? 420 GLY B C   1 
ATOM   6524 O  O   . GLY C 1 250 ? -16.172 3.444   -21.684 1   52.44  ? 420 GLY B O   1 
ATOM   6525 N  N   . VAL C 1 251 ? -16.315 2.146   -19.833 1   50.32  ? 421 VAL B N   1 
ATOM   6526 C  CA  . VAL C 1 251 ? -17.789 1.967   -19.951 1   52.64  ? 421 VAL B CA  1 
ATOM   6527 C  C   . VAL C 1 251 ? -18.535 3.283   -19.681 1   56.35  ? 421 VAL B C   1 
ATOM   6528 O  O   . VAL C 1 251 ? -19.659 3.42    -20.177 1   62.14  ? 421 VAL B O   1 
ATOM   6529 C  CB  . VAL C 1 251 ? -18.233 0.83    -19.017 1   49.68  ? 421 VAL B CB  1 
ATOM   6530 C  CG1 . VAL C 1 251 ? -17.82  -0.528  -19.564 1   48.08  ? 421 VAL B CG1 1 
ATOM   6531 C  CG2 . VAL C 1 251 ? -17.731 1.028   -17.595 1   46.65  ? 421 VAL B CG2 1 
ATOM   6532 N  N   . SER C 1 252 ? -17.932 4.217   -18.952 1   54.49  ? 422 SER B N   1 
ATOM   6533 C  CA  . SER C 1 252 ? -18.609 5.493   -18.613 1   54.47  ? 422 SER B CA  1 
ATOM   6534 C  C   . SER C 1 252 ? -18.816 6.333   -19.877 1   56.14  ? 422 SER B C   1 
ATOM   6535 O  O   . SER C 1 252 ? -19.475 7.38    -19.786 1   61.46  ? 422 SER B O   1 
ATOM   6536 C  CB  . SER C 1 252 ? -17.832 6.261   -17.592 1   54.12  ? 422 SER B CB  1 
ATOM   6537 O  OG  . SER C 1 252 ? -16.708 6.893   -18.179 1   57.06  ? 422 SER B OG  1 
ATOM   6538 N  N   . LEU C 1 253 ? -18.272 5.888   -21.005 1   56.75  ? 423 LEU B N   1 
ATOM   6539 C  CA  . LEU C 1 253 ? -18.359 6.656   -22.268 1   56.4   ? 423 LEU B CA  1 
ATOM   6540 C  C   . LEU C 1 253 ? -19.453 6.042   -23.146 1   56.82  ? 423 LEU B C   1 
ATOM   6541 O  O   . LEU C 1 253 ? -19.884 6.702   -24.107 1   59.22  ? 423 LEU B O   1 
ATOM   6542 C  CB  . LEU C 1 253 ? -16.98  6.614   -22.918 1   55.94  ? 423 LEU B CB  1 
ATOM   6543 C  CG  . LEU C 1 253 ? -15.827 7.125   -22.051 1   57.67  ? 423 LEU B CG  1 
ATOM   6544 C  CD1 . LEU C 1 253 ? -14.492 6.737   -22.649 1   57.84  ? 423 LEU B CD1 1 
ATOM   6545 C  CD2 . LEU C 1 253 ? -15.921 8.629   -21.888 1   61.03  ? 423 LEU B CD2 1 
ATOM   6546 N  N   . LEU C 1 254 ? -19.912 4.846   -22.789 1   53.93  ? 424 LEU B N   1 
ATOM   6547 C  CA  . LEU C 1 254 ? -20.993 4.18    -23.55  1   53.64  ? 424 LEU B CA  1 
ATOM   6548 C  C   . LEU C 1 254 ? -22.27  5.014   -23.437 1   55.93  ? 424 LEU B C   1 
ATOM   6549 O  O   . LEU C 1 254 ? -22.484 5.631   -22.384 1   57.56  ? 424 LEU B O   1 
ATOM   6550 C  CB  . LEU C 1 254 ? -21.196 2.76    -23.03  1   49.34  ? 424 LEU B CB  1 
ATOM   6551 C  CG  . LEU C 1 254 ? -20.096 1.748   -23.353 1   46.68  ? 424 LEU B CG  1 
ATOM   6552 C  CD1 . LEU C 1 254 ? -20.371 0.453   -22.613 1   42.34  ? 424 LEU B CD1 1 
ATOM   6553 C  CD2 . LEU C 1 254 ? -20.044 1.502   -24.846 1   45.26  ? 424 LEU B CD2 1 
ATOM   6554 N  N   . ASN C 1 255 ? -23.085 5.019   -24.49  1   59.34  ? 425 ASN B N   1 
ATOM   6555 C  CA  . ASN C 1 255 ? -24.298 5.821   -24.493 1   58.57  ? 425 ASN B CA  1 
ATOM   6556 C  C   . ASN C 1 255 ? -25.412 5.06    -23.774 1   57.72  ? 425 ASN B C   1 
ATOM   6557 O  O   . ASN C 1 255 ? -25.678 3.909   -24.122 1   58.55  ? 425 ASN B O   1 
ATOM   6558 C  CB  . ASN C 1 255 ? -24.651 6.22    -25.918 1   60.18  ? 425 ASN B CB  1 
ATOM   6559 C  CG  . ASN C 1 255 ? -23.92  7.468   -26.363 1   65.2   ? 425 ASN B CG  1 
ATOM   6560 O  OD1 . ASN C 1 255 ? -23.941 7.817   -27.545 1   70.54  ? 425 ASN B OD1 1 
ATOM   6561 N  ND2 . ASN C 1 255 ? -23.273 8.17    -25.445 1   66.47  ? 425 ASN B ND2 1 
ATOM   6562 N  N   . PRO C 1 256 ? -26.082 5.643   -22.746 1   55.28  ? 426 PRO B N   1 
ATOM   6563 C  CA  . PRO C 1 256 ? -27.247 4.998   -22.136 1   56.36  ? 426 PRO B CA  1 
ATOM   6564 C  C   . PRO C 1 256 ? -28.399 4.872   -23.138 1   61.5   ? 426 PRO B C   1 
ATOM   6565 O  O   . PRO C 1 256 ? -28.562 5.749   -24     1   62.57  ? 426 PRO B O   1 
ATOM   6566 C  CB  . PRO C 1 256 ? -27.608 5.952   -20.993 1   53.05  ? 426 PRO B CB  1 
ATOM   6567 C  CG  . PRO C 1 256 ? -27.109 7.295   -21.456 1   53.09  ? 426 PRO B CG  1 
ATOM   6568 C  CD  . PRO C 1 256 ? -25.798 6.952   -22.138 1   54.04  ? 426 PRO B CD  1 
ATOM   6569 N  N   . PRO C 1 257 ? -29.258 3.823   -23.013 1   59.81  ? 427 PRO B N   1 
ATOM   6570 C  CA  . PRO C 1 257 ? -30.395 3.649   -23.923 1   57.86  ? 427 PRO B CA  1 
ATOM   6571 C  C   . PRO C 1 257 ? -31.477 4.685   -23.605 1   59.12  ? 427 PRO B C   1 
ATOM   6572 O  O   . PRO C 1 257 ? -31.619 5.069   -22.448 1   55.83  ? 427 PRO B O   1 
ATOM   6573 C  CB  . PRO C 1 257 ? -30.829 2.189   -23.697 1   53.74  ? 427 PRO B CB  1 
ATOM   6574 C  CG  . PRO C 1 257 ? -30.376 1.859   -22.301 1   52.38  ? 427 PRO B CG  1 
ATOM   6575 C  CD  . PRO C 1 257 ? -29.22  2.798   -21.951 1   54.44  ? 427 PRO B CD  1 
ATOM   6576 N  N   . GLU C 1 258 ? -32.186 5.18    -24.639 1   67.58  ? 428 GLU B N   1 
ATOM   6577 C  CA  . GLU C 1 258 ? -33.22  6.199   -24.465 1   72.86  ? 428 GLU B CA  1 
ATOM   6578 C  C   . GLU C 1 258 ? -34.407 5.66    -23.658 1   75.27  ? 428 GLU B C   1 
ATOM   6579 O  O   . GLU C 1 258 ? -35.009 6.411   -22.889 1   79.24  ? 428 GLU B O   1 
ATOM   6580 C  CB  . GLU C 1 258 ? -33.784 6.748   -25.773 1   76.74  ? 428 GLU B CB  1 
ATOM   6581 C  CG  . GLU C 1 258 ? -32.827 7.593   -26.617 1   83.81  ? 428 GLU B CG  1 
ATOM   6582 C  CD  . GLU C 1 258 ? -33.373 7.923   -28.016 1   96.72  ? 428 GLU B CD  1 
ATOM   6583 O  OE1 . GLU C 1 258 ? -34.622 7.968   -28.202 1   95.84  ? 428 GLU B OE1 1 
ATOM   6584 O  OE2 . GLU C 1 258 ? -32.555 8.101   -28.958 1   103.72 ? 428 GLU B OE2 1 
ATOM   6585 N  N   . THR C 1 259 ? -34.749 4.37    -23.859 1   72.21  ? 429 THR B N   1 
ATOM   6586 C  CA  . THR C 1 259 ? -35.907 3.698   -23.266 1   71.49  ? 429 THR B CA  1 
ATOM   6587 C  C   . THR C 1 259 ? -35.567 2.244   -22.941 1   70.71  ? 429 THR B C   1 
ATOM   6588 O  O   . THR C 1 259 ? -34.682 1.668   -23.572 1   69.97  ? 429 THR B O   1 
ATOM   6589 C  CB  . THR C 1 259 ? -37.116 3.695   -24.216 1   73     ? 429 THR B CB  1 
ATOM   6590 O  OG1 . THR C 1 259 ? -36.91  2.735   -25.254 1   67.27  ? 429 THR B OG1 1 
ATOM   6591 C  CG2 . THR C 1 259 ? -37.488 5.06    -24.769 1   74.45  ? 429 THR B CG2 1 
ATOM   6592 N  N   . LEU C 1 260 ? -36.385 1.605   -22.088 1   71.57  ? 430 LEU B N   1 
ATOM   6593 C  CA  . LEU C 1 260 ? -36.093 0.267   -21.593 1   74.26  ? 430 LEU B CA  1 
ATOM   6594 C  C   . LEU C 1 260 ? -36.984 -0.818  -22.199 1   82.49  ? 430 LEU B C   1 
ATOM   6595 O  O   . LEU C 1 260 ? -36.622 -1.999  -22.153 1   80.82  ? 430 LEU B O   1 
ATOM   6596 C  CB  . LEU C 1 260 ? -36.185 0.235   -20.07  1   67.69  ? 430 LEU B CB  1 
ATOM   6597 C  CG  . LEU C 1 260 ? -35.083 0.985   -19.325 1   65.03  ? 430 LEU B CG  1 
ATOM   6598 C  CD1 . LEU C 1 260 ? -35.26  0.744   -17.836 1   65.25  ? 430 LEU B CD1 1 
ATOM   6599 C  CD2 . LEU C 1 260 ? -33.698 0.567   -19.782 1   60.35  ? 430 LEU B CD2 1 
ATOM   6600 N  N   . ASN C 1 261 ? -38.169 -0.432  -22.695 1   95.55  ? 431 ASN B N   1 
ATOM   6601 C  CA  . ASN C 1 261 ? -39.175 -1.405  -23.105 1   105.31 ? 431 ASN B CA  1 
ATOM   6602 C  C   . ASN C 1 261 ? -39.603 -2.242  -21.894 1   105.96 ? 431 ASN B C   1 
ATOM   6603 O  O   . ASN C 1 261 ? -39.68  -3.469  -21.99  1   99.86  ? 431 ASN B O   1 
ATOM   6604 C  CB  . ASN C 1 261 ? -38.698 -2.263  -24.281 1   108.75 ? 431 ASN B CB  1 
ATOM   6605 C  CG  . ASN C 1 261 ? -38.771 -1.564  -25.626 1   120.63 ? 431 ASN B CG  1 
ATOM   6606 O  OD1 . ASN C 1 261 ? -38.467 -2.172  -26.66  1   120.72 ? 431 ASN B OD1 1 
ATOM   6607 N  ND2 . ASN C 1 261 ? -39.196 -0.307  -25.653 1   118.48 ? 431 ASN B ND2 1 
ATOM   6608 N  N   . VAL C 1 262 ? -39.853 -1.562  -20.76  1   103.76 ? 432 VAL B N   1 
ATOM   6609 C  CA  . VAL C 1 262 ? -40.338 -2.195  -19.538 1   99.61  ? 432 VAL B CA  1 
ATOM   6610 C  C   . VAL C 1 262 ? -41.549 -1.389  -19.024 1   108.38 ? 432 VAL B C   1 
ATOM   6611 O  O   . VAL C 1 262 ? -42.702 -1.738  -19.409 1   104.45 ? 432 VAL B O   1 
ATOM   6612 C  CB  . VAL C 1 262 ? -39.341 -2.557  -18.401 1   91.26  ? 432 VAL B CB  1 
ATOM   6613 C  CG1 . VAL C 1 262 ? -38.16  -3.386  -18.889 1   86.9   ? 432 VAL B CG1 1 
ATOM   6614 C  CG2 . VAL C 1 262 ? -38.831 -1.371  -17.583 1   81.55  ? 432 VAL B CG2 1 
ATOM   6615 N  N   . SER D 2 4   ? -14.911 4.692   28.662  1   73.39  ? 0   SER C N   1 
ATOM   6616 C  CA  . SER D 2 4   ? -16.382 4.534   28.532  1   72.38  ? 0   SER C CA  1 
ATOM   6617 C  C   . SER D 2 4   ? -16.992 5.9     28.215  1   71.55  ? 0   SER C C   1 
ATOM   6618 O  O   . SER D 2 4   ? -17.66  6.032   27.172  1   70.67  ? 0   SER C O   1 
ATOM   6619 C  CB  . SER D 2 4   ? -16.961 3.941   29.781  1   70.67  ? 0   SER C CB  1 
ATOM   6620 O  OG  . SER D 2 4   ? -16.488 2.617   29.985  1   72.34  ? 0   SER C OG  1 
ATOM   6621 N  N   . MET D 2 5   ? -16.75  6.872   29.085  1   67.88  ? 1   MET C N   1 
ATOM   6622 C  CA  . MET D 2 5   ? -17.233 8.246   28.83   1   67.82  ? 1   MET C CA  1 
ATOM   6623 C  C   . MET D 2 5   ? -16.041 9.048   28.313  1   70.48  ? 1   MET C C   1 
ATOM   6624 O  O   . MET D 2 5   ? -16.071 10.285  28.401  1   69.84  ? 1   MET C O   1 
ATOM   6625 C  CB  . MET D 2 5   ? -17.792 8.84    30.122  1   66.75  ? 1   MET C CB  1 
ATOM   6626 C  CG  . MET D 2 5   ? -18.663 7.885   30.9    1   62.79  ? 1   MET C CG  1 
ATOM   6627 S  SD  . MET D 2 5   ? -20.289 7.828   30.128  1   67.11  ? 1   MET C SD  1 
ATOM   6628 C  CE  . MET D 2 5   ? -20.586 9.595   30.018  1   66.39  ? 1   MET C CE  1 
ATOM   6629 N  N   . GLU D 2 6   ? -15.041 8.35    27.776  1   75.16  ? 2   GLU C N   1 
ATOM   6630 C  CA  . GLU D 2 6   ? -13.837 9.011   27.305  1   77.06  ? 2   GLU C CA  1 
ATOM   6631 C  C   . GLU D 2 6   ? -14.223 9.952   26.168  1   70.37  ? 2   GLU C C   1 
ATOM   6632 O  O   . GLU D 2 6   ? -13.591 10.985  25.987  1   69.98  ? 2   GLU C O   1 
ATOM   6633 C  CB  . GLU D 2 6   ? -12.735 8.002   26.96   1   85.38  ? 2   GLU C CB  1 
ATOM   6634 C  CG  . GLU D 2 6   ? -11.428 8.665   26.53   1   103.31 ? 2   GLU C CG  1 
ATOM   6635 C  CD  . GLU D 2 6   ? -10.682 9.501   27.569  1   120.3  ? 2   GLU C CD  1 
ATOM   6636 O  OE1 . GLU D 2 6   ? -11.027 9.409   28.775  1   126.13 ? 2   GLU C OE1 1 
ATOM   6637 O  OE2 . GLU D 2 6   ? -9.742  10.244  27.184  1   121.15 ? 2   GLU C OE2 1 
ATOM   6638 N  N   . ASN D 2 7   ? -15.293 9.605   25.435  1   67.49  ? 3   ASN C N   1 
ATOM   6639 C  CA  . ASN D 2 7   ? -15.688 10.367  24.255  1   65.46  ? 3   ASN C CA  1 
ATOM   6640 C  C   . ASN D 2 7   ? -16.647 11.499  24.595  1   61.77  ? 3   ASN C C   1 
ATOM   6641 O  O   . ASN D 2 7   ? -16.873 12.34   23.735  1   61.9   ? 3   ASN C O   1 
ATOM   6642 C  CB  . ASN D 2 7   ? -16.358 9.525   23.177  1   65.03  ? 3   ASN C CB  1 
ATOM   6643 C  CG  . ASN D 2 7   ? -15.406 8.528   22.562  1   69.28  ? 3   ASN C CG  1 
ATOM   6644 O  OD1 . ASN D 2 7   ? -14.228 8.845   22.312  1   69.62  ? 3   ASN C OD1 1 
ATOM   6645 N  ND2 . ASN D 2 7   ? -15.891 7.305   22.366  1   67.42  ? 3   ASN C ND2 1 
ATOM   6646 N  N   . PHE D 2 8   ? -17.224 11.494  25.806  1   58.1   ? 4   PHE C N   1 
ATOM   6647 C  CA  . PHE D 2 8   ? -18.092 12.578  26.252  1   57.23  ? 4   PHE C CA  1 
ATOM   6648 C  C   . PHE D 2 8   ? -17.312 13.618  27.051  1   59.41  ? 4   PHE C C   1 
ATOM   6649 O  O   . PHE D 2 8   ? -16.513 13.263  27.91   1   61.97  ? 4   PHE C O   1 
ATOM   6650 C  CB  . PHE D 2 8   ? -19.287 12.021  27.023  1   52.73  ? 4   PHE C CB  1 
ATOM   6651 C  CG  . PHE D 2 8   ? -20.194 11.232  26.098  1   51.11  ? 4   PHE C CG  1 
ATOM   6652 C  CD1 . PHE D 2 8   ? -20.92  11.886  25.113  1   49.76  ? 4   PHE C CD1 1 
ATOM   6653 C  CD2 . PHE D 2 8   ? -20.293 9.845   26.199  1   51.2   ? 4   PHE C CD2 1 
ATOM   6654 C  CE1 . PHE D 2 8   ? -21.742 11.169  24.258  1   50.64  ? 4   PHE C CE1 1 
ATOM   6655 C  CE2 . PHE D 2 8   ? -21.11  9.13    25.337  1   50.05  ? 4   PHE C CE2 1 
ATOM   6656 C  CZ  . PHE D 2 8   ? -21.831 9.791   24.365  1   50.95  ? 4   PHE C CZ  1 
ATOM   6657 N  N   . GLN D 2 9   ? -17.564 14.897  26.747  1   60.64  ? 5   GLN C N   1 
ATOM   6658 C  CA  . GLN D 2 9   ? -16.996 16.037  27.454  1   64.68  ? 5   GLN C CA  1 
ATOM   6659 C  C   . GLN D 2 9   ? -18.094 16.748  28.247  1   63.22  ? 5   GLN C C   1 
ATOM   6660 O  O   . GLN D 2 9   ? -19.094 17.184  27.674  1   62.16  ? 5   GLN C O   1 
ATOM   6661 C  CB  . GLN D 2 9   ? -16.462 17.009  26.403  1   70.04  ? 5   GLN C CB  1 
ATOM   6662 C  CG  . GLN D 2 9   ? -16.084 18.387  26.928  1   78.24  ? 5   GLN C CG  1 
ATOM   6663 C  CD  . GLN D 2 9   ? -14.742 18.372  27.622  1   87.94  ? 5   GLN C CD  1 
ATOM   6664 O  OE1 . GLN D 2 9   ? -13.699 18.34   26.963  1   93.51  ? 5   GLN C OE1 1 
ATOM   6665 N  NE2 . GLN D 2 9   ? -14.756 18.364  28.953  1   86.32  ? 5   GLN C NE2 1 
ATOM   6666 N  N   . LYS D 2 10  ? -17.905 16.897  29.562  1   63.42  ? 6   LYS C N   1 
ATOM   6667 C  CA  . LYS D 2 10  ? -18.889 17.594  30.38   1   64.92  ? 6   LYS C CA  1 
ATOM   6668 C  C   . LYS D 2 10  ? -18.983 19.054  29.931  1   62.89  ? 6   LYS C C   1 
ATOM   6669 O  O   . LYS D 2 10  ? -17.955 19.679  29.731  1   67.47  ? 6   LYS C O   1 
ATOM   6670 C  CB  . LYS D 2 10  ? -18.428 17.508  31.838  1   72.14  ? 6   LYS C CB  1 
ATOM   6671 C  CG  . LYS D 2 10  ? -19.557 17.453  32.863  1   80.47  ? 6   LYS C CG  1 
ATOM   6672 C  CD  . LYS D 2 10  ? -19.111 17.032  34.263  1   90     ? 6   LYS C CD  1 
ATOM   6673 C  CE  . LYS D 2 10  ? -18.507 18.163  35.056  1   95.67  ? 6   LYS C CE  1 
ATOM   6674 N  NZ  . LYS D 2 10  ? -18.629 17.92   36.496  1   97.3   ? 6   LYS C NZ  1 
ATOM   6675 N  N   . VAL D 2 11  ? -20.189 19.603  29.766  1   58.19  ? 7   VAL C N   1 
ATOM   6676 C  CA  . VAL D 2 11  ? -20.335 21.014  29.418  1   59.42  ? 7   VAL C CA  1 
ATOM   6677 C  C   . VAL D 2 11  ? -20.86  21.813  30.62   1   61.96  ? 7   VAL C C   1 
ATOM   6678 O  O   . VAL D 2 11  ? -20.298 22.833  30.988  1   63.53  ? 7   VAL C O   1 
ATOM   6679 C  CB  . VAL D 2 11  ? -21.229 21.238  28.184  1   57.78  ? 7   VAL C CB  1 
ATOM   6680 C  CG1 . VAL D 2 11  ? -21.592 22.704  27.992  1   56.01  ? 7   VAL C CG1 1 
ATOM   6681 C  CG2 . VAL D 2 11  ? -20.61  20.649  26.921  1   59.06  ? 7   VAL C CG2 1 
ATOM   6682 N  N   . GLU D 2 12  ? -21.967 21.371  31.23   1   62.05  ? 8   GLU C N   1 
ATOM   6683 C  CA  . GLU D 2 12  ? -22.553 22.075  32.357  1   64.1   ? 8   GLU C CA  1 
ATOM   6684 C  C   . GLU D 2 12  ? -23.685 21.246  32.959  1   64.61  ? 8   GLU C C   1 
ATOM   6685 O  O   . GLU D 2 12  ? -24.247 20.407  32.254  1   63.53  ? 8   GLU C O   1 
ATOM   6686 C  CB  . GLU D 2 12  ? -23.059 23.424  31.848  1   66.79  ? 8   GLU C CB  1 
ATOM   6687 C  CG  . GLU D 2 12  ? -24.254 23.284  30.912  1   67.12  ? 8   GLU C CG  1 
ATOM   6688 C  CD  . GLU D 2 12  ? -24.828 24.609  30.478  1   71.64  ? 8   GLU C CD  1 
ATOM   6689 O  OE1 . GLU D 2 12  ? -24.003 25.439  30.042  1   75.41  ? 8   GLU C OE1 1 
ATOM   6690 O  OE2 . GLU D 2 12  ? -26.066 24.791  30.561  1   74.36  ? 8   GLU C OE2 1 
ATOM   6691 N  N   . LYS D 2 13  ? -24.01  21.493  34.247  1   69.19  ? 9   LYS C N   1 
ATOM   6692 C  CA  . LYS D 2 13  ? -25.101 20.827  34.954  1   72.88  ? 9   LYS C CA  1 
ATOM   6693 C  C   . LYS D 2 13  ? -26.417 21.434  34.481  1   71.14  ? 9   LYS C C   1 
ATOM   6694 O  O   . LYS D 2 13  ? -26.471 22.646  34.266  1   76.34  ? 9   LYS C O   1 
ATOM   6695 C  CB  . LYS D 2 13  ? -24.938 21.035  36.462  1   83.76  ? 9   LYS C CB  1 
ATOM   6696 C  CG  . LYS D 2 13  ? -25.578 19.984  37.367  1   92.83  ? 9   LYS C CG  1 
ATOM   6697 C  CD  . LYS D 2 13  ? -25.18  19.985  38.843  1   112.52 ? 9   LYS C CD  1 
ATOM   6698 C  CE  . LYS D 2 13  ? -25.589 21.131  39.745  1   119.53 ? 9   LYS C CE  1 
ATOM   6699 N  NZ  . LYS D 2 13  ? -24.713 22.305  39.602  1   118.96 ? 9   LYS C NZ  1 
ATOM   6700 N  N   . ILE D 2 14  ? -27.455 20.607  34.269  1   63.69  ? 10  ILE C N   1 
ATOM   6701 C  CA  . ILE D 2 14  ? -28.695 21.149  33.729  1   65.42  ? 10  ILE C CA  1 
ATOM   6702 C  C   . ILE D 2 14  ? -29.89  20.862  34.636  1   68.97  ? 10  ILE C C   1 
ATOM   6703 O  O   . ILE D 2 14  ? -31.018 21.264  34.354  1   72.37  ? 10  ILE C O   1 
ATOM   6704 C  CB  . ILE D 2 14  ? -28.949 20.752  32.26   1   62.13  ? 10  ILE C CB  1 
ATOM   6705 C  CG1 . ILE D 2 14  ? -29.204 19.291  32.058  1   60.85  ? 10  ILE C CG1 1 
ATOM   6706 C  CG2 . ILE D 2 14  ? -27.811 21.229  31.365  1   66.26  ? 10  ILE C CG2 1 
ATOM   6707 C  CD1 . ILE D 2 14  ? -29.149 18.884  30.59   1   61.68  ? 10  ILE C CD1 1 
ATOM   6708 N  N   . GLY D 2 15  ? -29.617 20.132  35.704  1   68.81  ? 11  GLY C N   1 
ATOM   6709 C  CA  . GLY D 2 15  ? -30.702 19.819  36.631  1   74.53  ? 11  GLY C CA  1 
ATOM   6710 C  C   . GLY D 2 15  ? -30.375 18.626  37.477  1   80.72  ? 11  GLY C C   1 
ATOM   6711 O  O   . GLY D 2 15  ? -29.344 17.983  37.225  1   81.82  ? 11  GLY C O   1 
ATOM   6712 N  N   . GLU D 2 16  ? -31.216 18.368  38.47   1   90.63  ? 12  GLU C N   1 
ATOM   6713 C  CA  . GLU D 2 16  ? -31.039 17.178  39.325  1   91.3   ? 12  GLU C CA  1 
ATOM   6714 C  C   . GLU D 2 16  ? -32.393 16.476  39.36   1   96.08  ? 12  GLU C C   1 
ATOM   6715 O  O   . GLU D 2 16  ? -33.418 17.178  39.338  1   111.25 ? 12  GLU C O   1 
ATOM   6716 C  CB  . GLU D 2 16  ? -30.587 17.571  40.728  1   86.94  ? 12  GLU C CB  1 
ATOM   6717 C  CG  . GLU D 2 16  ? -29.147 18.074  40.773  1   96.56  ? 12  GLU C CG  1 
ATOM   6718 C  CD  . GLU D 2 16  ? -28.48  17.855  42.116  1   100.58 ? 12  GLU C CD  1 
ATOM   6719 O  OE1 . GLU D 2 16  ? -27.998 18.843  42.704  1   100.56 ? 12  GLU C OE1 1 
ATOM   6720 O  OE2 . GLU D 2 16  ? -28.448 16.695  42.574  1   101.64 ? 12  GLU C OE2 1 
ATOM   6721 N  N   . GLY D 2 17  ? -32.388 15.148  39.379  1   103.62 ? 13  GLY C N   1 
ATOM   6722 C  CA  . GLY D 2 17  ? -33.649 14.396  39.428  1   105.44 ? 13  GLY C CA  1 
ATOM   6723 C  C   . GLY D 2 17  ? -33.597 13.354  40.517  1   110.84 ? 13  GLY C C   1 
ATOM   6724 O  O   . GLY D 2 17  ? -32.745 13.477  41.417  1   107.9  ? 13  GLY C O   1 
ATOM   6725 N  N   . THR D 2 18  ? -34.466 12.352  40.433  1   122.09 ? 14  THR C N   1 
ATOM   6726 C  CA  . THR D 2 18  ? -34.519 11.323  41.482  1   119.68 ? 14  THR C CA  1 
ATOM   6727 C  C   . THR D 2 18  ? -33.137 10.736  41.641  1   119    ? 14  THR C C   1 
ATOM   6728 O  O   . THR D 2 18  ? -32.755 10.429  42.787  1   116.4  ? 14  THR C O   1 
ATOM   6729 C  CB  . THR D 2 18  ? -35.553 10.271  41.094  1   116.83 ? 14  THR C CB  1 
ATOM   6730 O  OG1 . THR D 2 18  ? -35.419 9.239   42.066  1   120.5  ? 14  THR C OG1 1 
ATOM   6731 C  CG2 . THR D 2 18  ? -35.317 9.702   39.707  1   113.96 ? 14  THR C CG2 1 
ATOM   6732 N  N   . TYR D 2 19  ? -32.41  10.593  40.533  1   117.36 ? 15  TYR C N   1 
ATOM   6733 C  CA  . TYR D 2 19  ? -31.227 9.706   40.471  1   113.47 ? 15  TYR C CA  1 
ATOM   6734 C  C   . TYR D 2 19  ? -30.029 10.43   40.977  1   113.01 ? 15  TYR C C   1 
ATOM   6735 O  O   . TYR D 2 19  ? -29.312 9.928   41.862  1   111.17 ? 15  TYR C O   1 
ATOM   6736 C  CB  . TYR D 2 19  ? -30.897 9.454   39.009  1   109.43 ? 15  TYR C CB  1 
ATOM   6737 C  CG  . TYR D 2 19  ? -31.977 8.705   38.253  1   104.99 ? 15  TYR C CG  1 
ATOM   6738 C  CD1 . TYR D 2 19  ? -32.37  7.432   38.638  1   85.83  ? 15  TYR C CD1 1 
ATOM   6739 C  CD2 . TYR D 2 19  ? -32.588 9.278   37.152  1   110.83 ? 15  TYR C CD2 1 
ATOM   6740 C  CE1 . TYR D 2 19  ? -33.338 6.743   37.934  1   81.95  ? 15  TYR C CE1 1 
ATOM   6741 C  CE2 . TYR D 2 19  ? -33.568 8.604   36.452  1   104.17 ? 15  TYR C CE2 1 
ATOM   6742 C  CZ  . TYR D 2 19  ? -33.941 7.333   36.839  1   84.75  ? 15  TYR C CZ  1 
ATOM   6743 O  OH  . TYR D 2 19  ? -34.906 6.687   36.13   1   76.26  ? 15  TYR C OH  1 
ATOM   6744 N  N   . GLY D 2 20  ? -29.777 11.587  40.38   1   108.16 ? 16  GLY C N   1 
ATOM   6745 C  CA  . GLY D 2 20  ? -28.635 12.398  40.811  1   103.24 ? 16  GLY C CA  1 
ATOM   6746 C  C   . GLY D 2 20  ? -28.567 13.654  39.985  1   100.88 ? 16  GLY C C   1 
ATOM   6747 O  O   . GLY D 2 20  ? -29.411 14.539  40.192  1   99.48  ? 16  GLY C O   1 
ATOM   6748 N  N   . VAL D 2 21  ? -27.625 13.71   39.051  1   94.9   ? 17  VAL C N   1 
ATOM   6749 C  CA  . VAL D 2 21  ? -27.448 14.974  38.292  1   84.56  ? 17  VAL C CA  1 
ATOM   6750 C  C   . VAL D 2 21  ? -27.612 14.725  36.79   1   77.65  ? 17  VAL C C   1 
ATOM   6751 O  O   . VAL D 2 21  ? -27.22  13.64   36.328  1   69.04  ? 17  VAL C O   1 
ATOM   6752 C  CB  . VAL D 2 21  ? -26.062 15.55   38.611  1   91.33  ? 17  VAL C CB  1 
ATOM   6753 C  CG1 . VAL D 2 21  ? -25.784 16.78   37.773  1   92.87  ? 17  VAL C CG1 1 
ATOM   6754 C  CG2 . VAL D 2 21  ? -25.893 15.866  40.09   1   94.83  ? 17  VAL C CG2 1 
ATOM   6755 N  N   . VAL D 2 22  ? -28.228 15.673  36.086  1   66.38  ? 18  VAL C N   1 
ATOM   6756 C  CA  . VAL D 2 22  ? -28.318 15.588  34.605  1   60.89  ? 18  VAL C CA  1 
ATOM   6757 C  C   . VAL D 2 22  ? -27.355 16.642  34.045  1   63.87  ? 18  VAL C C   1 
ATOM   6758 O  O   . VAL D 2 22  ? -27.409 17.793  34.507  1   64.63  ? 18  VAL C O   1 
ATOM   6759 C  CB  . VAL D 2 22  ? -29.756 15.799  34.107  1   58.67  ? 18  VAL C CB  1 
ATOM   6760 C  CG1 . VAL D 2 22  ? -29.936 15.312  32.677  1   55.05  ? 18  VAL C CG1 1 
ATOM   6761 C  CG2 . VAL D 2 22  ? -30.773 15.145  35.033  1   57.33  ? 18  VAL C CG2 1 
ATOM   6762 N  N   . TYR D 2 23  ? -26.489 16.248  33.115  1   59.92  ? 19  TYR C N   1 
ATOM   6763 C  CA  . TYR D 2 23  ? -25.523 17.167  32.539  1   57.28  ? 19  TYR C CA  1 
ATOM   6764 C  C   . TYR D 2 23  ? -25.678 17.198  31.035  1   52.04  ? 19  TYR C C   1 
ATOM   6765 O  O   . TYR D 2 23  ? -26.037 16.196  30.422  1   49.45  ? 19  TYR C O   1 
ATOM   6766 C  CB  . TYR D 2 23  ? -24.079 16.707  32.698  1   61.15  ? 19  TYR C CB  1 
ATOM   6767 C  CG  . TYR D 2 23  ? -23.627 16.449  34.124  1   69.91  ? 19  TYR C CG  1 
ATOM   6768 C  CD1 . TYR D 2 23  ? -23.943 15.251  34.771  1   73.77  ? 19  TYR C CD1 1 
ATOM   6769 C  CD2 . TYR D 2 23  ? -22.846 17.387  34.8    1   71.5   ? 19  TYR C CD2 1 
ATOM   6770 C  CE1 . TYR D 2 23  ? -23.471 14.989  36.049  1   80.32  ? 19  TYR C CE1 1 
ATOM   6771 C  CE2 . TYR D 2 23  ? -22.399 17.149  36.086  1   76.84  ? 19  TYR C CE2 1 
ATOM   6772 C  CZ  . TYR D 2 23  ? -22.708 15.946  36.702  1   82.34  ? 19  TYR C CZ  1 
ATOM   6773 O  OH  . TYR D 2 23  ? -22.285 15.722  37.975  1   96.61  ? 19  TYR C OH  1 
ATOM   6774 N  N   . LYS D 2 24  ? -25.364 18.366  30.469  1   51.77  ? 20  LYS C N   1 
ATOM   6775 C  CA  . LYS D 2 24  ? -25.172 18.508  29.039  1   49.9   ? 20  LYS C CA  1 
ATOM   6776 C  C   . LYS D 2 24  ? -23.709 18.222  28.747  1   51.48  ? 20  LYS C C   1 
ATOM   6777 O  O   . LYS D 2 24  ? -22.825 18.693  29.456  1   51.43  ? 20  LYS C O   1 
ATOM   6778 C  CB  . LYS D 2 24  ? -25.583 19.906  28.595  1   49.99  ? 20  LYS C CB  1 
ATOM   6779 C  CG  . LYS D 2 24  ? -24.948 20.432  27.326  1   52.6   ? 20  LYS C CG  1 
ATOM   6780 C  CD  . LYS D 2 24  ? -25.662 21.69   26.856  1   52.8   ? 20  LYS C CD  1 
ATOM   6781 C  CE  . LYS D 2 24  ? -24.886 22.458  25.86   1   57.44  ? 20  LYS C CE  1 
ATOM   6782 N  NZ  . LYS D 2 24  ? -25.831 23.315  25.134  1   64.61  ? 20  LYS C NZ  1 
ATOM   6783 N  N   . ALA D 2 25  ? -23.491 17.394  27.718  1   51.33  ? 21  ALA C N   1 
ATOM   6784 C  CA  . ALA D 2 25  ? -22.171 16.948  27.31   1   51.95  ? 21  ALA C CA  1 
ATOM   6785 C  C   . ALA D 2 25  ? -22.101 17.003  25.787  1   52.75  ? 21  ALA C C   1 
ATOM   6786 O  O   . ALA D 2 25  ? -23.139 17.093  25.134  1   52.86  ? 21  ALA C O   1 
ATOM   6787 C  CB  . ALA D 2 25  ? -21.947 15.549  27.837  1   49.41  ? 21  ALA C CB  1 
ATOM   6788 N  N   . ARG D 2 26  ? -20.889 16.874  25.256  1   54.42  ? 22  ARG C N   1 
ATOM   6789 C  CA  . ARG D 2 26  ? -20.698 16.846  23.79   1   57.36  ? 22  ARG C CA  1 
ATOM   6790 C  C   . ARG D 2 26  ? -19.923 15.585  23.406  1   56.59  ? 22  ARG C C   1 
ATOM   6791 O  O   . ARG D 2 26  ? -18.954 15.258  24.106  1   56.75  ? 22  ARG C O   1 
ATOM   6792 C  CB  . ARG D 2 26  ? -19.891 18.052  23.313  1   64.43  ? 22  ARG C CB  1 
ATOM   6793 C  CG  . ARG D 2 26  ? -19.922 18.252  21.806  1   77.36  ? 22  ARG C CG  1 
ATOM   6794 C  CD  . ARG D 2 26  ? -19.112 19.47   21.401  1   88.21  ? 22  ARG C CD  1 
ATOM   6795 N  NE  . ARG D 2 26  ? -19.405 20.621  22.262  1   102.49 ? 22  ARG C NE  1 
ATOM   6796 C  CZ  . ARG D 2 26  ? -20.477 21.395  22.138  1   112.72 ? 22  ARG C CZ  1 
ATOM   6797 N  NH1 . ARG D 2 26  ? -20.968 21.655  20.94   1   107.22 ? 22  ARG C NH1 1 
ATOM   6798 N  NH2 . ARG D 2 26  ? -21.056 21.901  23.211  1   105.22 ? 22  ARG C NH2 1 
ATOM   6799 N  N   . ASN D 2 27  ? -20.349 14.909  22.341  1   53.27  ? 23  ASN C N   1 
ATOM   6800 C  CA  . ASN D 2 27  ? -19.575 13.748  21.844  1   53.86  ? 23  ASN C CA  1 
ATOM   6801 C  C   . ASN D 2 27  ? -18.352 14.306  21.127  1   56.1   ? 23  ASN C C   1 
ATOM   6802 O  O   . ASN D 2 27  ? -18.515 14.987  20.111  1   56.49  ? 23  ASN C O   1 
ATOM   6803 C  CB  . ASN D 2 27  ? -20.405 12.84   20.949  1   53.07  ? 23  ASN C CB  1 
ATOM   6804 C  CG  . ASN D 2 27  ? -19.712 11.541  20.613  1   52.14  ? 23  ASN C CG  1 
ATOM   6805 O  OD1 . ASN D 2 27  ? -18.646 11.54   19.99   1   53.01  ? 23  ASN C OD1 1 
ATOM   6806 N  ND2 . ASN D 2 27  ? -20.313 10.423  20.99   1   48.79  ? 23  ASN C ND2 1 
ATOM   6807 N  N   . LYS D 2 28  ? -17.173 14.003  21.641  1   57.62  ? 24  LYS C N   1 
ATOM   6808 C  CA  . LYS D 2 28  ? -15.968 14.566  21.066  1   62.18  ? 24  LYS C CA  1 
ATOM   6809 C  C   . LYS D 2 28  ? -15.798 14.132  19.616  1   64.45  ? 24  LYS C C   1 
ATOM   6810 O  O   . LYS D 2 28  ? -15.254 14.886  18.81   1   69.15  ? 24  LYS C O   1 
ATOM   6811 C  CB  . LYS D 2 28  ? -14.747 14.189  21.91   1   66.52  ? 24  LYS C CB  1 
ATOM   6812 C  CG  . LYS D 2 28  ? -14.7   14.954  23.22   1   70.93  ? 24  LYS C CG  1 
ATOM   6813 C  CD  . LYS D 2 28  ? -13.438 14.819  24.058  1   77.32  ? 24  LYS C CD  1 
ATOM   6814 C  CE  . LYS D 2 28  ? -13.526 13.755  25.108  1   78.83  ? 24  LYS C CE  1 
ATOM   6815 N  NZ  . LYS D 2 28  ? -12.601 14.069  26.205  1   82.73  ? 24  LYS C NZ  1 
ATOM   6816 N  N   . LEU D 2 29  ? -16.215 12.907  19.279  1   63.7   ? 25  LEU C N   1 
ATOM   6817 C  CA  . LEU D 2 29  ? -15.922 12.407  17.945  1   65.38  ? 25  LEU C CA  1 
ATOM   6818 C  C   . LEU D 2 29  ? -17     12.8    16.921  1   66.43  ? 25  LEU C C   1 
ATOM   6819 O  O   . LEU D 2 29  ? -16.663 13.05   15.758  1   71.05  ? 25  LEU C O   1 
ATOM   6820 C  CB  . LEU D 2 29  ? -15.656 10.913  18.023  1   63.12  ? 25  LEU C CB  1 
ATOM   6821 C  CG  . LEU D 2 29  ? -14.318 10.529  18.656  1   63.14  ? 25  LEU C CG  1 
ATOM   6822 C  CD1 . LEU D 2 29  ? -14.257 9.022   18.869  1   61.72  ? 25  LEU C CD1 1 
ATOM   6823 C  CD2 . LEU D 2 29  ? -13.139 11.013  17.833  1   63.89  ? 25  LEU C CD2 1 
ATOM   6824 N  N   . THR D 2 30  ? -18.272 12.906  17.356  1   60.44  ? 26  THR C N   1 
ATOM   6825 C  CA  . THR D 2 30  ? -19.375 13.239  16.46   1   57.38  ? 26  THR C CA  1 
ATOM   6826 C  C   . THR D 2 30  ? -19.855 14.694  16.574  1   57.59  ? 26  THR C C   1 
ATOM   6827 O  O   . THR D 2 30  ? -20.517 15.197  15.669  1   57.58  ? 26  THR C O   1 
ATOM   6828 C  CB  . THR D 2 30  ? -20.537 12.276  16.682  1   54.44  ? 26  THR C CB  1 
ATOM   6829 O  OG1 . THR D 2 30  ? -21.108 12.539  17.964  1   52.08  ? 26  THR C OG1 1 
ATOM   6830 C  CG2 . THR D 2 30  ? -20.11  10.828  16.535  1   53.81  ? 26  THR C CG2 1 
ATOM   6831 N  N   . GLY D 2 31  ? -19.601 15.375  17.698  1   58.06  ? 27  GLY C N   1 
ATOM   6832 C  CA  . GLY D 2 31  ? -20.157 16.708  17.928  1   57.79  ? 27  GLY C CA  1 
ATOM   6833 C  C   . GLY D 2 31  ? -21.598 16.688  18.458  1   56.98  ? 27  GLY C C   1 
ATOM   6834 O  O   . GLY D 2 31  ? -22.18  17.733  18.729  1   58.98  ? 27  GLY C O   1 
ATOM   6835 N  N   . GLU D 2 32  ? -22.211 15.505  18.564  1   56.99  ? 28  GLU C N   1 
ATOM   6836 C  CA  . GLU D 2 32  ? -23.573 15.41   19.074  1   56.05  ? 28  GLU C CA  1 
ATOM   6837 C  C   . GLU D 2 32  ? -23.603 15.992  20.484  1   56.33  ? 28  GLU C C   1 
ATOM   6838 O  O   . GLU D 2 32  ? -22.847 15.563  21.351  1   61.53  ? 28  GLU C O   1 
ATOM   6839 C  CB  . GLU D 2 32  ? -24.046 13.952  19.079  1   53.83  ? 28  GLU C CB  1 
ATOM   6840 C  CG  . GLU D 2 32  ? -25.485 13.795  19.556  1   51.21  ? 28  GLU C CG  1 
ATOM   6841 C  CD  . GLU D 2 32  ? -25.997 12.366  19.484  1   54.97  ? 28  GLU C CD  1 
ATOM   6842 O  OE1 . GLU D 2 32  ? -25.236 11.386  19.799  1   55.45  ? 28  GLU C OE1 1 
ATOM   6843 O  OE2 . GLU D 2 32  ? -27.219 12.261  19.164  1   56.85  ? 28  GLU C OE2 1 
ATOM   6844 N  N   . VAL D 2 33  ? -24.458 16.98   20.704  1   53.41  ? 29  VAL C N   1 
ATOM   6845 C  CA  . VAL D 2 33  ? -24.691 17.455  22.054  1   52.18  ? 29  VAL C CA  1 
ATOM   6846 C  C   . VAL D 2 33  ? -25.731 16.532  22.698  1   51.17  ? 29  VAL C C   1 
ATOM   6847 O  O   . VAL D 2 33  ? -26.706 16.161  22.047  1   53.12  ? 29  VAL C O   1 
ATOM   6848 C  CB  . VAL D 2 33  ? -25.163 18.923  22.006  1   50.69  ? 29  VAL C CB  1 
ATOM   6849 C  CG1 . VAL D 2 33  ? -25.503 19.431  23.403  1   47.21  ? 29  VAL C CG1 1 
ATOM   6850 C  CG2 . VAL D 2 33  ? -24.138 19.82   21.294  1   51.1   ? 29  VAL C CG2 1 
ATOM   6851 N  N   . VAL D 2 34  ? -25.514 16.142  23.962  1   47.63  ? 30  VAL C N   1 
ATOM   6852 C  CA  . VAL D 2 34  ? -26.372 15.157  24.613  1   45.42  ? 30  VAL C CA  1 
ATOM   6853 C  C   . VAL D 2 34  ? -26.724 15.639  26.021  1   45.55  ? 30  VAL C C   1 
ATOM   6854 O  O   . VAL D 2 34  ? -26.148 16.591  26.54   1   50.98  ? 30  VAL C O   1 
ATOM   6855 C  CB  . VAL D 2 34  ? -25.763 13.73   24.657  1   43.16  ? 30  VAL C CB  1 
ATOM   6856 C  CG1 . VAL D 2 34  ? -25.457 13.174  23.285  1   42.09  ? 30  VAL C CG1 1 
ATOM   6857 C  CG2 . VAL D 2 34  ? -24.508 13.653  25.508  1   42.87  ? 30  VAL C CG2 1 
ATOM   6858 N  N   . ALA D 2 35  ? -27.682 14.966  26.654  1   43.97  ? 31  ALA C N   1 
ATOM   6859 C  CA  . ALA D 2 35  ? -27.807 15.052  28.101  1   45.31  ? 31  ALA C CA  1 
ATOM   6860 C  C   . ALA D 2 35  ? -27.488 13.67   28.66   1   47.06  ? 31  ALA C C   1 
ATOM   6861 O  O   . ALA D 2 35  ? -27.895 12.662  28.053  1   48.92  ? 31  ALA C O   1 
ATOM   6862 C  CB  . ALA D 2 35  ? -29.195 15.526  28.494  1   43.06  ? 31  ALA C CB  1 
ATOM   6863 N  N   . LEU D 2 36  ? -26.718 13.648  29.756  1   47.89  ? 32  LEU C N   1 
ATOM   6864 C  CA  . LEU D 2 36  ? -26.306 12.431  30.443  1   48.4   ? 32  LEU C CA  1 
ATOM   6865 C  C   . LEU D 2 36  ? -26.96  12.412  31.812  1   50.65  ? 32  LEU C C   1 
ATOM   6866 O  O   . LEU D 2 36  ? -26.942 13.418  32.512  1   59.3   ? 32  LEU C O   1 
ATOM   6867 C  CB  . LEU D 2 36  ? -24.793 12.456  30.606  1   48.13  ? 32  LEU C CB  1 
ATOM   6868 C  CG  . LEU D 2 36  ? -23.982 12.428  29.31   1   50.81  ? 32  LEU C CG  1 
ATOM   6869 C  CD1 . LEU D 2 36  ? -22.505 12.546  29.668  1   52.46  ? 32  LEU C CD1 1 
ATOM   6870 C  CD2 . LEU D 2 36  ? -24.25  11.154  28.518  1   48.42  ? 32  LEU C CD2 1 
ATOM   6871 N  N   . LYS D 2 37  ? -27.523 11.272  32.199  1   50.77  ? 33  LYS C N   1 
ATOM   6872 C  CA  . LYS D 2 37  ? -28.107 11.133  33.523  1   49.4   ? 33  LYS C CA  1 
ATOM   6873 C  C   . LYS D 2 37  ? -27.241 10.142  34.29   1   49.1   ? 33  LYS C C   1 
ATOM   6874 O  O   . LYS D 2 37  ? -27.181 8.992   33.917  1   49.74  ? 33  LYS C O   1 
ATOM   6875 C  CB  . LYS D 2 37  ? -29.53  10.604  33.339  1   47.72  ? 33  LYS C CB  1 
ATOM   6876 C  CG  . LYS D 2 37  ? -30.637 11.175  34.194  1   48.04  ? 33  LYS C CG  1 
ATOM   6877 C  CD  . LYS D 2 37  ? -32.007 10.585  33.866  1   50.47  ? 33  LYS C CD  1 
ATOM   6878 C  CE  . LYS D 2 37  ? -33.154 11.461  34.284  1   58.45  ? 33  LYS C CE  1 
ATOM   6879 N  NZ  . LYS D 2 37  ? -34.355 11.34   33.457  1   55.21  ? 33  LYS C NZ  1 
ATOM   6880 N  N   . LYS D 2 38  ? -26.509 10.621  35.297  1   52.88  ? 34  LYS C N   1 
ATOM   6881 C  CA  . LYS D 2 38  ? -25.643 9.807   36.136  1   55.27  ? 34  LYS C CA  1 
ATOM   6882 C  C   . LYS D 2 38  ? -26.503 9.179   37.227  1   62.37  ? 34  LYS C C   1 
ATOM   6883 O  O   . LYS D 2 38  ? -27.153 9.907   37.977  1   72.81  ? 34  LYS C O   1 
ATOM   6884 C  CB  . LYS D 2 38  ? -24.585 10.703  36.785  1   56.12  ? 34  LYS C CB  1 
ATOM   6885 C  CG  . LYS D 2 38  ? -23.332 10.011  37.248  1   63.01  ? 34  LYS C CG  1 
ATOM   6886 C  CD  . LYS D 2 38  ? -22.392 10.811  38.148  1   71.01  ? 34  LYS C CD  1 
ATOM   6887 C  CE  . LYS D 2 38  ? -22.689 10.535  39.602  1   81.26  ? 34  LYS C CE  1 
ATOM   6888 N  NZ  . LYS D 2 38  ? -21.623 10.924  40.534  1   85.98  ? 34  LYS C NZ  1 
ATOM   6889 N  N   . ILE D 2 39  ? -26.541 7.835   37.277  1   62.11  ? 35  ILE C N   1 
ATOM   6890 C  CA  . ILE D 2 39  ? -27.257 7.089   38.312  1   58.67  ? 35  ILE C CA  1 
ATOM   6891 C  C   . ILE D 2 39  ? -26.282 6.248   39.13   1   64.78  ? 35  ILE C C   1 
ATOM   6892 O  O   . ILE D 2 39  ? -25.728 5.284   38.608  1   72.15  ? 35  ILE C O   1 
ATOM   6893 C  CB  . ILE D 2 39  ? -28.296 6.167   37.669  1   54.62  ? 35  ILE C CB  1 
ATOM   6894 C  CG1 . ILE D 2 39  ? -29.382 6.962   37.018  1   52.47  ? 35  ILE C CG1 1 
ATOM   6895 C  CG2 . ILE D 2 39  ? -28.848 5.188   38.702  1   55.5   ? 35  ILE C CG2 1 
ATOM   6896 C  CD1 . ILE D 2 39  ? -30.262 6.128   36.117  1   56.49  ? 35  ILE C CD1 1 
ATOM   6897 N  N   . ARG D 2 40  ? -26.12  6.61    40.399  1   72.34  ? 36  ARG C N   1 
ATOM   6898 C  CA  . ARG D 2 40  ? -25.185 5.878   41.285  1   77.66  ? 36  ARG C CA  1 
ATOM   6899 C  C   . ARG D 2 40  ? -25.781 4.524   41.655  1   76.95  ? 36  ARG C C   1 
ATOM   6900 O  O   . ARG D 2 40  ? -26.955 4.47    42.06   1   74.09  ? 36  ARG C O   1 
ATOM   6901 C  CB  . ARG D 2 40  ? -24.854 6.656   42.56   1   86.65  ? 36  ARG C CB  1 
ATOM   6902 C  CG  . ARG D 2 40  ? -23.557 6.188   43.2    1   99.04  ? 36  ARG C CG  1 
ATOM   6903 C  CD  . ARG D 2 40  ? -22.443 6.155   42.172  1   110.22 ? 36  ARG C CD  1 
ATOM   6904 N  NE  . ARG D 2 40  ? -21.859 7.486   41.984  1   121.86 ? 36  ARG C NE  1 
ATOM   6905 C  CZ  . ARG D 2 40  ? -20.975 8.027   42.809  1   128.34 ? 36  ARG C CZ  1 
ATOM   6906 N  NH1 . ARG D 2 40  ? -19.942 7.318   43.226  1   131.9  ? 36  ARG C NH1 1 
ATOM   6907 N  NH2 . ARG D 2 40  ? -21.129 9.273   43.217  1   121.47 ? 36  ARG C NH2 1 
ATOM   6908 N  N   . LEU D 2 41  ? -24.98  3.482   41.518  1   74.43  ? 37  LEU C N   1 
ATOM   6909 C  CA  . LEU D 2 41  ? -25.404 2.126   41.818  1   70.82  ? 37  LEU C CA  1 
ATOM   6910 C  C   . LEU D 2 41  ? -25.001 1.761   43.242  1   77.1   ? 37  LEU C C   1 
ATOM   6911 O  O   . LEU D 2 41  ? -23.835 1.889   43.64   1   78.03  ? 37  LEU C O   1 
ATOM   6912 C  CB  . LEU D 2 41  ? -24.803 1.159   40.806  1   63.03  ? 37  LEU C CB  1 
ATOM   6913 C  CG  . LEU D 2 41  ? -25.186 1.414   39.35   1   59.68  ? 37  LEU C CG  1 
ATOM   6914 C  CD1 . LEU D 2 41  ? -24.872 0.205   38.494  1   53.64  ? 37  LEU C CD1 1 
ATOM   6915 C  CD2 . LEU D 2 41  ? -26.662 1.757   39.274  1   60.27  ? 37  LEU C CD2 1 
ATOM   6916 N  N   . ASP D 2 42  ? -25.991 1.26    43.987  1   76.41  ? 38  ASP C N   1 
ATOM   6917 C  CA  . ASP D 2 42  ? -25.777 0.84    45.365  1   76.13  ? 38  ASP C CA  1 
ATOM   6918 C  C   . ASP D 2 42  ? -25.161 -0.563  45.396  1   68.57  ? 38  ASP C C   1 
ATOM   6919 O  O   . ASP D 2 42  ? -25.846 -1.531  45.706  1   69.72  ? 38  ASP C O   1 
ATOM   6920 C  CB  . ASP D 2 42  ? -27.063 1.02    46.161  1   74.66  ? 38  ASP C CB  1 
ATOM   6921 C  CG  . ASP D 2 42  ? -27.486 2.467   46.348  1   74.48  ? 38  ASP C CG  1 
ATOM   6922 O  OD1 . ASP D 2 42  ? -26.748 3.177   47.068  1   75.56  ? 38  ASP C OD1 1 
ATOM   6923 O  OD2 . ASP D 2 42  ? -28.51  2.876   45.734  1   69.37  ? 38  ASP C OD2 1 
ATOM   6924 N  N   . THR D 2 43  ? -23.856 -0.672  45.134  1   62.46  ? 39  THR C N   1 
ATOM   6925 C  CA  . THR D 2 43  ? -23.253 -1.963  44.822  1   60.85  ? 39  THR C CA  1 
ATOM   6926 C  C   . THR D 2 43  ? -23.1   -2.888  46.044  1   59.84  ? 39  THR C C   1 
ATOM   6927 O  O   . THR D 2 43  ? -22.795 -4.067  45.907  1   60.14  ? 39  THR C O   1 
ATOM   6928 C  CB  . THR D 2 43  ? -21.941 -1.728  44.068  1   62.04  ? 39  THR C CB  1 
ATOM   6929 O  OG1 . THR D 2 43  ? -21.052 -0.977  44.896  1   69.2   ? 39  THR C OG1 1 
ATOM   6930 C  CG2 . THR D 2 43  ? -22.156 -0.962  42.776  1   57.88  ? 39  THR C CG2 1 
ATOM   6931 N  N   . GLU D 2 44  ? -23.315 -2.379  47.255  1   59.86  ? 40  GLU C N   1 
ATOM   6932 C  CA  . GLU D 2 44  ? -23.263 -3.222  48.442  1   61.65  ? 40  GLU C CA  1 
ATOM   6933 C  C   . GLU D 2 44  ? -24.643 -3.306  49.102  1   61.57  ? 40  GLU C C   1 
ATOM   6934 O  O   . GLU D 2 44  ? -24.829 -4.073  50.045  1   64.75  ? 40  GLU C O   1 
ATOM   6935 C  CB  . GLU D 2 44  ? -22.241 -2.708  49.46   1   62.28  ? 40  GLU C CB  1 
ATOM   6936 C  CG  . GLU D 2 44  ? -20.794 -2.716  48.969  1   63.37  ? 40  GLU C CG  1 
ATOM   6937 C  CD  . GLU D 2 44  ? -20.405 -1.724  47.875  1   61.83  ? 40  GLU C CD  1 
ATOM   6938 O  OE1 . GLU D 2 44  ? -19.846 -2.143  46.822  1   60.56  ? 40  GLU C OE1 1 
ATOM   6939 O  OE2 . GLU D 2 44  ? -20.693 -0.516  48.068  1   61.24  ? 40  GLU C OE2 1 
ATOM   6940 N  N   . THR D 2 45  ? -25.606 -2.507  48.63   1   58.75  ? 41  THR C N   1 
ATOM   6941 C  CA  . THR D 2 45  ? -26.852 -2.355  49.366  1   59.32  ? 41  THR C CA  1 
ATOM   6942 C  C   . THR D 2 45  ? -28.064 -2.711  48.497  1   56.49  ? 41  THR C C   1 
ATOM   6943 O  O   . THR D 2 45  ? -28.489 -3.858  48.523  1   57.95  ? 41  THR C O   1 
ATOM   6944 C  CB  . THR D 2 45  ? -26.922 -1.045  50.17   1   60.08  ? 41  THR C CB  1 
ATOM   6945 O  OG1 . THR D 2 45  ? -26.703 0.103   49.353  1   59.31  ? 41  THR C OG1 1 
ATOM   6946 C  CG2 . THR D 2 45  ? -25.91  -1.012  51.303  1   61.83  ? 41  THR C CG2 1 
ATOM   6947 N  N   A GLU D 2 46  ? -28.604 -1.773  47.715  0.5 53.57  ? 42  GLU C N   1 
ATOM   6948 N  N   B GLU D 2 46  ? -28.551 -1.729  47.724  0.5 54.49  ? 42  GLU C N   1 
ATOM   6949 C  CA  A GLU D 2 46  ? -29.889 -2.04   47.084  0.5 51.95  ? 42  GLU C CA  1 
ATOM   6950 C  CA  B GLU D 2 46  ? -29.852 -1.757  47.068  0.5 53.48  ? 42  GLU C CA  1 
ATOM   6951 C  C   A GLU D 2 46  ? -29.794 -2.134  45.555  0.5 50.49  ? 42  GLU C C   1 
ATOM   6952 C  C   B GLU D 2 46  ? -29.748 -2.271  45.626  0.5 51.79  ? 42  GLU C C   1 
ATOM   6953 O  O   A GLU D 2 46  ? -30.826 -2.237  44.895  0.5 49.51  ? 42  GLU C O   1 
ATOM   6954 O  O   B GLU D 2 46  ? -30.729 -2.796  45.105  0.5 51.51  ? 42  GLU C O   1 
ATOM   6955 C  CB  A GLU D 2 46  ? -30.992 -1.101  47.589  0.5 50.52  ? 42  GLU C CB  1 
ATOM   6956 C  CB  B GLU D 2 46  ? -30.558 -0.392  47.116  0.5 52.57  ? 42  GLU C CB  1 
ATOM   6957 C  CG  A GLU D 2 46  ? -31.283 -1.191  49.091  0.5 51.49  ? 42  GLU C CG  1 
ATOM   6958 C  CG  B GLU D 2 46  ? -31.272 -0.061  48.434  0.5 54.81  ? 42  GLU C CG  1 
ATOM   6959 C  CD  A GLU D 2 46  ? -31.716 -2.517  49.714  0.5 52.56  ? 42  GLU C CD  1 
ATOM   6960 C  CD  B GLU D 2 46  ? -32.236 1.133   48.45   0.5 54.08  ? 42  GLU C CD  1 
ATOM   6961 O  OE1 A GLU D 2 46  ? -32.663 -3.179  49.227  0.5 51.37  ? 42  GLU C OE1 1 
ATOM   6962 O  OE1 B GLU D 2 46  ? -33.31  1.076   47.818  0.5 52.14  ? 42  GLU C OE1 1 
ATOM   6963 O  OE2 A GLU D 2 46  ? -31.103 -2.878  50.743  0.5 54.54  ? 42  GLU C OE2 1 
ATOM   6964 O  OE2 B GLU D 2 46  ? -31.916 2.155   49.088  0.5 54.93  ? 42  GLU C OE2 1 
ATOM   6965 N  N   . GLY D 2 47  ? -28.578 -2.107  44.984  1   50.62  ? 43  GLY C N   1 
ATOM   6966 C  CA  . GLY D 2 47  ? -28.377 -2.433  43.575  1   48.23  ? 43  GLY C CA  1 
ATOM   6967 C  C   . GLY D 2 47  ? -28.955 -1.347  42.67   1   48.15  ? 43  GLY C C   1 
ATOM   6968 O  O   . GLY D 2 47  ? -29.004 -0.18   43.041  1   51.7   ? 43  GLY C O   1 
ATOM   6969 N  N   . VAL D 2 48  ? -29.406 -1.716  41.473  1   45.91  ? 44  VAL C N   1 
ATOM   6970 C  CA  . VAL D 2 48  ? -29.886 -0.737  40.517  1   44.51  ? 44  VAL C CA  1 
ATOM   6971 C  C   . VAL D 2 48  ? -31.283 -0.294  40.922  1   47.01  ? 44  VAL C C   1 
ATOM   6972 O  O   . VAL D 2 48  ? -32.165 -1.132  41.089  1   49.45  ? 44  VAL C O   1 
ATOM   6973 C  CB  . VAL D 2 48  ? -29.952 -1.357  39.116  1   43.01  ? 44  VAL C CB  1 
ATOM   6974 C  CG1 . VAL D 2 48  ? -30.4   -0.332  38.085  1   40.32  ? 44  VAL C CG1 1 
ATOM   6975 C  CG2 . VAL D 2 48  ? -28.634 -2.016  38.731  1   43.78  ? 44  VAL C CG2 1 
ATOM   6976 N  N   . PRO D 2 49  ? -31.557 1.028   41.052  1   46.86  ? 45  PRO C N   1 
ATOM   6977 C  CA  . PRO D 2 49  ? -32.851 1.47    41.575  1   44.34  ? 45  PRO C CA  1 
ATOM   6978 C  C   . PRO D 2 49  ? -33.917 1.116   40.553  1   45.52  ? 45  PRO C C   1 
ATOM   6979 O  O   . PRO D 2 49  ? -33.683 1.214   39.334  1   46.27  ? 45  PRO C O   1 
ATOM   6980 C  CB  . PRO D 2 49  ? -32.726 2.992   41.791  1   42.43  ? 45  PRO C CB  1 
ATOM   6981 C  CG  . PRO D 2 49  ? -31.417 3.387   41.151  1   41.93  ? 45  PRO C CG  1 
ATOM   6982 C  CD  . PRO D 2 49  ? -30.647 2.144   40.72   1   44.15  ? 45  PRO C CD  1 
ATOM   6983 N  N   . SER D 2 50  ? -35.098 0.741   41.067  1   47.34  ? 46  SER C N   1 
ATOM   6984 C  CA  . SER D 2 50  ? -36.224 0.352   40.231  1   47.15  ? 46  SER C CA  1 
ATOM   6985 C  C   . SER D 2 50  ? -36.708 1.514   39.368  1   46.32  ? 46  SER C C   1 
ATOM   6986 O  O   . SER D 2 50  ? -37.174 1.301   38.248  1   47.1   ? 46  SER C O   1 
ATOM   6987 C  CB  . SER D 2 50  ? -37.314 -0.252  41.036  1   49.87  ? 46  SER C CB  1 
ATOM   6988 O  OG  . SER D 2 50  ? -37.703 0.672   42.037  1   54.41  ? 46  SER C OG  1 
ATOM   6989 N  N   . THR D 2 51  ? -36.551 2.749   39.859  1   48.35  ? 47  THR C N   1 
ATOM   6990 C  CA  . THR D 2 51  ? -36.758 3.942   39.039  1   48.89  ? 47  THR C CA  1 
ATOM   6991 C  C   . THR D 2 51  ? -36.044 3.803   37.697  1   48.09  ? 47  THR C C   1 
ATOM   6992 O  O   . THR D 2 51  ? -36.645 4.017   36.654  1   48.88  ? 47  THR C O   1 
ATOM   6993 C  CB  . THR D 2 51  ? -36.213 5.2     39.699  1   50.48  ? 47  THR C CB  1 
ATOM   6994 O  OG1 . THR D 2 51  ? -37.003 5.525   40.822  1   52.17  ? 47  THR C OG1 1 
ATOM   6995 C  CG2 . THR D 2 51  ? -36.473 6.407   38.827  1   54.12  ? 47  THR C CG2 1 
ATOM   6996 N  N   . ALA D 2 52  ? -34.745 3.479   37.734  1   45.89  ? 48  ALA C N   1 
ATOM   6997 C  CA  . ALA D 2 52  ? -33.954 3.382   36.523  1   43.76  ? 48  ALA C CA  1 
ATOM   6998 C  C   . ALA D 2 52  ? -34.336 2.139   35.703  1   46.09  ? 48  ALA C C   1 
ATOM   6999 O  O   . ALA D 2 52  ? -34.347 2.178   34.47   1   44.12  ? 48  ALA C O   1 
ATOM   7000 C  CB  . ALA D 2 52  ? -32.504 3.401   36.906  1   42.81  ? 48  ALA C CB  1 
ATOM   7001 N  N   . ILE D 2 53  ? -34.681 1.036   36.387  1   45.95  ? 49  ILE C N   1 
ATOM   7002 C  CA  . ILE D 2 53  ? -35.123 -0.164  35.689  1   44.75  ? 49  ILE C CA  1 
ATOM   7003 C  C   . ILE D 2 53  ? -36.361 0.147   34.841  1   49.06  ? 49  ILE C C   1 
ATOM   7004 O  O   . ILE D 2 53  ? -36.454 -0.245  33.675  1   51.25  ? 49  ILE C O   1 
ATOM   7005 C  CB  . ILE D 2 53  ? -35.315 -1.32   36.684  1   42.02  ? 49  ILE C CB  1 
ATOM   7006 C  CG1 . ILE D 2 53  ? -33.964 -1.781  37.19   1   41.18  ? 49  ILE C CG1 1 
ATOM   7007 C  CG2 . ILE D 2 53  ? -36.106 -2.475  36.073  1   40.95  ? 49  ILE C CG2 1 
ATOM   7008 C  CD1 . ILE D 2 53  ? -34.001 -2.434  38.548  1   42.93  ? 49  ILE C CD1 1 
ATOM   7009 N  N   . ARG D 2 54  ? -37.288 0.918   35.407  1   49.79  ? 50  ARG C N   1 
ATOM   7010 C  CA  . ARG D 2 54  ? -38.488 1.267   34.668  1   48.62  ? 50  ARG C CA  1 
ATOM   7011 C  C   . ARG D 2 54  ? -38.165 2.267   33.572  1   48.26  ? 50  ARG C C   1 
ATOM   7012 O  O   . ARG D 2 54  ? -38.479 1.991   32.418  1   50.94  ? 50  ARG C O   1 
ATOM   7013 C  CB  . ARG D 2 54  ? -39.578 1.78    35.608  1   50.17  ? 50  ARG C CB  1 
ATOM   7014 C  CG  . ARG D 2 54  ? -40.261 0.638   36.352  1   50.63  ? 50  ARG C CG  1 
ATOM   7015 C  CD  . ARG D 2 54  ? -41.105 1.192   37.494  1   48.83  ? 50  ARG C CD  1 
ATOM   7016 N  NE  . ARG D 2 54  ? -41.814 0.077   38.109  1   48.23  ? 50  ARG C NE  1 
ATOM   7017 C  CZ  . ARG D 2 54  ? -42.602 0.231   39.15   1   51.53  ? 50  ARG C CZ  1 
ATOM   7018 N  NH1 . ARG D 2 54  ? -42.848 1.437   39.642  1   47.99  ? 50  ARG C NH1 1 
ATOM   7019 N  NH2 . ARG D 2 54  ? -43.155 -0.84   39.693  1   54.64  ? 50  ARG C NH2 1 
ATOM   7020 N  N   . GLU D 2 55  ? -37.535 3.402   33.926  1   47.69  ? 51  GLU C N   1 
ATOM   7021 C  CA  . GLU D 2 55  ? -37.221 4.426   32.937  1   47.53  ? 51  GLU C CA  1 
ATOM   7022 C  C   . GLU D 2 55  ? -36.538 3.794   31.712  1   49.91  ? 51  GLU C C   1 
ATOM   7023 O  O   . GLU D 2 55  ? -37.032 3.911   30.59   1   53     ? 51  GLU C O   1 
ATOM   7024 C  CB  . GLU D 2 55  ? -36.427 5.588   33.53   1   43.98  ? 51  GLU C CB  1 
ATOM   7025 C  CG  . GLU D 2 55  ? -36.031 6.59    32.458  1   47.68  ? 51  GLU C CG  1 
ATOM   7026 C  CD  . GLU D 2 55  ? -35.566 7.993   32.826  1   51.41  ? 51  GLU C CD  1 
ATOM   7027 O  OE1 . GLU D 2 55  ? -35.069 8.166   33.969  1   42.81  ? 51  GLU C OE1 1 
ATOM   7028 O  OE2 . GLU D 2 55  ? -35.791 8.917   31.949  1   54.42  ? 51  GLU C OE2 1 
ATOM   7029 N  N   . ILE D 2 56  ? -35.434 3.073   31.928  1   47.09  ? 52  ILE C N   1 
ATOM   7030 C  CA  . ILE D 2 56  ? -34.659 2.501   30.833  1   47.49  ? 52  ILE C CA  1 
ATOM   7031 C  C   . ILE D 2 56  ? -35.517 1.537   30.007  1   49.14  ? 52  ILE C C   1 
ATOM   7032 O  O   . ILE D 2 56  ? -35.513 1.635   28.781  1   49.77  ? 52  ILE C O   1 
ATOM   7033 C  CB  . ILE D 2 56  ? -33.349 1.839   31.343  1   44.81  ? 52  ILE C CB  1 
ATOM   7034 C  CG1 . ILE D 2 56  ? -32.414 2.854   31.979  1   41.24  ? 52  ILE C CG1 1 
ATOM   7035 C  CG2 . ILE D 2 56  ? -32.62  1.077   30.239  1   41.7   ? 52  ILE C CG2 1 
ATOM   7036 C  CD1 . ILE D 2 56  ? -31.454 2.31    33.02   1   41.23  ? 52  ILE C CD1 1 
ATOM   7037 N  N   . SER D 2 57  ? -36.202 0.586   30.665  1   49.96  ? 53  SER C N   1 
ATOM   7038 C  CA  . SER D 2 57  ? -36.871 -0.52   29.972  1   51.48  ? 53  SER C CA  1 
ATOM   7039 C  C   . SER D 2 57  ? -38.044 -0.006  29.149  1   52.57  ? 53  SER C C   1 
ATOM   7040 O  O   . SER D 2 57  ? -38.345 -0.565  28.102  1   57.04  ? 53  SER C O   1 
ATOM   7041 C  CB  . SER D 2 57  ? -37.347 -1.627  30.91   1   50.85  ? 53  SER C CB  1 
ATOM   7042 O  OG  . SER D 2 57  ? -38.158 -1.114  31.966  1   51.4   ? 53  SER C OG  1 
ATOM   7043 N  N   . LEU D 2 58  ? -38.711 1.041   29.644  1   51.5   ? 54  LEU C N   1 
ATOM   7044 C  CA  . LEU D 2 58  ? -39.874 1.581   28.967  1   53.41  ? 54  LEU C CA  1 
ATOM   7045 C  C   . LEU D 2 58  ? -39.458 2.519   27.837  1   55.24  ? 54  LEU C C   1 
ATOM   7046 O  O   . LEU D 2 58  ? -40.069 2.471   26.763  1   59.1   ? 54  LEU C O   1 
ATOM   7047 C  CB  . LEU D 2 58  ? -40.823 2.211   29.978  1   52.86  ? 54  LEU C CB  1 
ATOM   7048 C  CG  . LEU D 2 58  ? -41.312 1.256   31.08   1   53.09  ? 54  LEU C CG  1 
ATOM   7049 C  CD1 . LEU D 2 58  ? -42.098 1.957   32.188  1   49.46  ? 54  LEU C CD1 1 
ATOM   7050 C  CD2 . LEU D 2 58  ? -42.128 0.092   30.534  1   55.57  ? 54  LEU C CD2 1 
ATOM   7051 N  N   . LEU D 2 59  ? -38.398 3.324   28.049  1   52.26  ? 55  LEU C N   1 
ATOM   7052 C  CA  . LEU D 2 59  ? -37.892 4.205   26.997  1   50.81  ? 55  LEU C CA  1 
ATOM   7053 C  C   . LEU D 2 59  ? -37.284 3.429   25.817  1   55.95  ? 55  LEU C C   1 
ATOM   7054 O  O   . LEU D 2 59  ? -37.265 3.912   24.684  1   59.02  ? 55  LEU C O   1 
ATOM   7055 C  CB  . LEU D 2 59  ? -36.874 5.181   27.569  1   48.13  ? 55  LEU C CB  1 
ATOM   7056 C  CG  . LEU D 2 59  ? -37.41  6.347   28.391  1   47.79  ? 55  LEU C CG  1 
ATOM   7057 C  CD1 . LEU D 2 59  ? -36.215 7.134   28.864  1   48.81  ? 55  LEU C CD1 1 
ATOM   7058 C  CD2 . LEU D 2 59  ? -38.302 7.217   27.566  1   47.24  ? 55  LEU C CD2 1 
ATOM   7059 N  N   . LYS D 2 60  ? -36.76  2.229   26.076  1   59.6   ? 56  LYS C N   1 
ATOM   7060 C  CA  . LYS D 2 60  ? -36.173 1.42    25.022  1   63.03  ? 56  LYS C CA  1 
ATOM   7061 C  C   . LYS D 2 60  ? -37.261 0.984   24.04   1   66.25  ? 56  LYS C C   1 
ATOM   7062 O  O   . LYS D 2 60  ? -37.001 0.785   22.851  1   68.13  ? 56  LYS C O   1 
ATOM   7063 C  CB  . LYS D 2 60  ? -35.357 0.261   25.609  1   64.87  ? 56  LYS C CB  1 
ATOM   7064 C  CG  . LYS D 2 60  ? -33.943 0.639   26.046  1   62     ? 56  LYS C CG  1 
ATOM   7065 C  CD  . LYS D 2 60  ? -33.047 -0.583  26.216  1   61.52  ? 56  LYS C CD  1 
ATOM   7066 C  CE  . LYS D 2 60  ? -32.779 -1.167  24.866  1   58.66  ? 56  LYS C CE  1 
ATOM   7067 N  NZ  . LYS D 2 60  ? -32.754 -2.631  24.849  1   57.9   ? 56  LYS C NZ  1 
ATOM   7068 N  N   . GLU D 2 61  ? -38.489 0.848   24.549  1   65.89  ? 57  GLU C N   1 
ATOM   7069 C  CA  . GLU D 2 61  ? -39.629 0.473   23.728  1   67.42  ? 57  GLU C CA  1 
ATOM   7070 C  C   . GLU D 2 61  ? -40.209 1.678   22.991  1   68.47  ? 57  GLU C C   1 
ATOM   7071 O  O   . GLU D 2 61  ? -40.569 1.562   21.82   1   77.41  ? 57  GLU C O   1 
ATOM   7072 C  CB  . GLU D 2 61  ? -40.712 -0.159  24.597  1   69.39  ? 57  GLU C CB  1 
ATOM   7073 C  CG  . GLU D 2 61  ? -40.299 -1.556  25.04   1   73.27  ? 57  GLU C CG  1 
ATOM   7074 C  CD  . GLU D 2 61  ? -41.409 -2.422  25.58   1   80.75  ? 57  GLU C CD  1 
ATOM   7075 O  OE1 . GLU D 2 61  ? -42.587 -1.983  25.466  1   86.07  ? 57  GLU C OE1 1 
ATOM   7076 O  OE2 . GLU D 2 61  ? -41.087 -3.526  26.092  1   80.98  ? 57  GLU C OE2 1 
ATOM   7077 N  N   . LEU D 2 62  ? -40.358 2.8     23.704  1   63.12  ? 58  LEU C N   1 
ATOM   7078 C  CA  . LEU D 2 62  ? -41.013 3.995   23.107  1   61.49  ? 58  LEU C CA  1 
ATOM   7079 C  C   . LEU D 2 62  ? -40.02  4.774   22.233  1   61.47  ? 58  LEU C C   1 
ATOM   7080 O  O   . LEU D 2 62  ? -39.083 5.378   22.796  1   61.63  ? 58  LEU C O   1 
ATOM   7081 C  CB  . LEU D 2 62  ? -41.578 4.872   24.223  1   59.87  ? 58  LEU C CB  1 
ATOM   7082 C  CG  . LEU D 2 62  ? -42.524 4.18    25.208  1   58.31  ? 58  LEU C CG  1 
ATOM   7083 C  CD1 . LEU D 2 62  ? -42.507 4.884   26.552  1   56.74  ? 58  LEU C CD1 1 
ATOM   7084 C  CD2 . LEU D 2 62  ? -43.939 4.107   24.661  1   59.12  ? 58  LEU C CD2 1 
ATOM   7085 N  N   . ASN D 2 63  ? -40.234 4.767   20.915  1   65.01  ? 59  ASN C N   1 
ATOM   7086 C  CA  . ASN D 2 63  ? -39.363 5.549   19.993  1   66.8   ? 59  ASN C CA  1 
ATOM   7087 C  C   . ASN D 2 63  ? -40.262 6.463   19.154  1   63.94  ? 59  ASN C C   1 
ATOM   7088 O  O   . ASN D 2 63  ? -40.322 6.268   17.921  1   71.38  ? 59  ASN C O   1 
ATOM   7089 C  CB  . ASN D 2 63  ? -38.459 4.632   19.178  1   75.04  ? 59  ASN C CB  1 
ATOM   7090 C  CG  . ASN D 2 63  ? -37.608 3.76    20.07   1   96.88  ? 59  ASN C CG  1 
ATOM   7091 O  OD1 . ASN D 2 63  ? -37.946 2.596   20.31   1   88.02  ? 59  ASN C OD1 1 
ATOM   7092 N  ND2 . ASN D 2 63  ? -36.515 4.306   20.583  1   112.27 ? 59  ASN C ND2 1 
ATOM   7093 N  N   . HIS D 2 64  ? -40.937 7.415   19.803  1   58.1   ? 60  HIS C N   1 
ATOM   7094 C  CA  . HIS D 2 64  ? -41.881 8.323   19.096  1   58.66  ? 60  HIS C CA  1 
ATOM   7095 C  C   . HIS D 2 64  ? -41.246 9.713   18.996  1   57.29  ? 60  HIS C C   1 
ATOM   7096 O  O   . HIS D 2 64  ? -40.552 10.115  19.956  1   60.07  ? 60  HIS C O   1 
ATOM   7097 C  CB  . HIS D 2 64  ? -43.212 8.338   19.857  1   56.6   ? 60  HIS C CB  1 
ATOM   7098 C  CG  . HIS D 2 64  ? -44.286 9.178   19.255  1   60.45  ? 60  HIS C CG  1 
ATOM   7099 N  ND1 . HIS D 2 64  ? -44.573 10.45   19.698  1   62.32  ? 60  HIS C ND1 1 
ATOM   7100 C  CD2 . HIS D 2 64  ? -45.144 8.932   18.258  1   61.03  ? 60  HIS C CD2 1 
ATOM   7101 C  CE1 . HIS D 2 64  ? -45.567 10.948  18.979  1   61.17  ? 60  HIS C CE1 1 
ATOM   7102 N  NE2 . HIS D 2 64  ? -45.931 10.043  18.1    1   59.2   ? 60  HIS C NE2 1 
ATOM   7103 N  N   . PRO D 2 65  ? -41.449 10.488  17.903  1   54.58  ? 61  PRO C N   1 
ATOM   7104 C  CA  . PRO D 2 65  ? -40.921 11.854  17.858  1   54.62  ? 61  PRO C CA  1 
ATOM   7105 C  C   . PRO D 2 65  ? -41.299 12.801  18.99   1   55.94  ? 61  PRO C C   1 
ATOM   7106 O  O   . PRO D 2 65  ? -40.734 13.885  19.043  1   60.48  ? 61  PRO C O   1 
ATOM   7107 C  CB  . PRO D 2 65  ? -41.387 12.398  16.503  1   53.64  ? 61  PRO C CB  1 
ATOM   7108 C  CG  . PRO D 2 65  ? -42.588 11.535  16.166  1   55.37  ? 61  PRO C CG  1 
ATOM   7109 C  CD  . PRO D 2 65  ? -42.289 10.156  16.746  1   53.63  ? 61  PRO C CD  1 
ATOM   7110 N  N   . ASN D 2 66  ? -42.256 12.422  19.856  1   53.15  ? 62  ASN C N   1 
ATOM   7111 C  CA  . ASN D 2 66  ? -42.632 13.286  20.968  1   53.18  ? 62  ASN C CA  1 
ATOM   7112 C  C   . ASN D 2 66  ? -42.322 12.63   22.32   1   55.96  ? 62  ASN C C   1 
ATOM   7113 O  O   . ASN D 2 66  ? -42.835 13.049  23.364  1   58.65  ? 62  ASN C O   1 
ATOM   7114 C  CB  . ASN D 2 66  ? -44.082 13.743  20.878  1   52.03  ? 62  ASN C CB  1 
ATOM   7115 C  CG  . ASN D 2 66  ? -44.335 14.525  19.611  1   56.14  ? 62  ASN C CG  1 
ATOM   7116 O  OD1 . ASN D 2 66  ? -45.141 14.098  18.778  1   64.28  ? 62  ASN C OD1 1 
ATOM   7117 N  ND2 . ASN D 2 66  ? -43.687 15.666  19.432  1   52.14  ? 62  ASN C ND2 1 
ATOM   7118 N  N   . ILE D 2 67  ? -41.474 11.61   22.29   1   50.17  ? 63  ILE C N   1 
ATOM   7119 C  CA  . ILE D 2 67  ? -41.001 10.996  23.557  1   48.96  ? 63  ILE C CA  1 
ATOM   7120 C  C   . ILE D 2 67  ? -39.477 11.168  23.542  1   50.28  ? 63  ILE C C   1 
ATOM   7121 O  O   . ILE D 2 67  ? -38.875 10.933  22.485  1   50.2   ? 63  ILE C O   1 
ATOM   7122 C  CB  . ILE D 2 67  ? -41.452 9.531   23.673  1   48.42  ? 63  ILE C CB  1 
ATOM   7123 C  CG1 . ILE D 2 67  ? -42.962 9.429   23.846  1   46.38  ? 63  ILE C CG1 1 
ATOM   7124 C  CG2 . ILE D 2 67  ? -40.708 8.811   24.796  1   47.29  ? 63  ILE C CG2 1 
ATOM   7125 C  CD1 . ILE D 2 67  ? -43.518 8.046   23.574  1   45.82  ? 63  ILE C CD1 1 
ATOM   7126 N  N   . VAL D 2 68  ? -38.893 11.619  24.65   1   49.02  ? 64  VAL C N   1 
ATOM   7127 C  CA  . VAL D 2 68  ? -37.423 11.87   24.7    1   48.85  ? 64  VAL C CA  1 
ATOM   7128 C  C   . VAL D 2 68  ? -36.705 10.593  24.246  1   48.62  ? 64  VAL C C   1 
ATOM   7129 O  O   . VAL D 2 68  ? -37.145 9.493   24.61   1   46.75  ? 64  VAL C O   1 
ATOM   7130 C  CB  . VAL D 2 68  ? -36.927 12.361  26.076  1   47.1   ? 64  VAL C CB  1 
ATOM   7131 C  CG1 . VAL D 2 68  ? -37.037 11.297  27.159  1   47.62  ? 64  VAL C CG1 1 
ATOM   7132 C  CG2 . VAL D 2 68  ? -35.522 12.941  26.011  1   46.59  ? 64  VAL C CG2 1 
ATOM   7133 N  N   . LYS D 2 69  ? -35.629 10.75   23.484  1   51.08  ? 65  LYS C N   1 
ATOM   7134 C  CA  . LYS D 2 69  ? -34.936 9.565   22.937  1   54.74  ? 65  LYS C CA  1 
ATOM   7135 C  C   . LYS D 2 69  ? -33.748 9.163   23.807  1   52.36  ? 65  LYS C C   1 
ATOM   7136 O  O   . LYS D 2 69  ? -32.864 10.001  24.032  1   51.68  ? 65  LYS C O   1 
ATOM   7137 C  CB  . LYS D 2 69  ? -34.442 9.812   21.509  1   62.24  ? 65  LYS C CB  1 
ATOM   7138 C  CG  . LYS D 2 69  ? -34.644 8.645   20.561  1   71.88  ? 65  LYS C CG  1 
ATOM   7139 C  CD  . LYS D 2 69  ? -33.486 7.656   20.573  1   89.33  ? 65  LYS C CD  1 
ATOM   7140 C  CE  . LYS D 2 69  ? -33.771 6.388   19.839  1   91.56  ? 65  LYS C CE  1 
ATOM   7141 N  NZ  . LYS D 2 69  ? -32.621 5.483   19.907  1   83.49  ? 65  LYS C NZ  1 
ATOM   7142 N  N   . LEU D 2 70  ? -33.754 7.92    24.274  1   49.81  ? 66  LEU C N   1 
ATOM   7143 C  CA  . LEU D 2 70  ? -32.589 7.383   25.004  1   48.8   ? 66  LEU C CA  1 
ATOM   7144 C  C   . LEU D 2 70  ? -31.684 6.786   23.93   1   50.21  ? 66  LEU C C   1 
ATOM   7145 O  O   . LEU D 2 70  ? -32.117 5.845   23.255  1   52.24  ? 66  LEU C O   1 
ATOM   7146 C  CB  . LEU D 2 70  ? -33.044 6.337   26.016  1   46.53  ? 66  LEU C CB  1 
ATOM   7147 C  CG  . LEU D 2 70  ? -31.947 5.657   26.836  1   46.37  ? 66  LEU C CG  1 
ATOM   7148 C  CD1 . LEU D 2 70  ? -31.373 6.645   27.827  1   46.94  ? 66  LEU C CD1 1 
ATOM   7149 C  CD2 . LEU D 2 70  ? -32.573 4.484   27.559  1   47.77  ? 66  LEU C CD2 1 
ATOM   7150 N  N   . LEU D 2 71  ? -30.498 7.349   23.753  1   49.79  ? 67  LEU C N   1 
ATOM   7151 C  CA  . LEU D 2 71  ? -29.616 6.894   22.66   1   47.2   ? 67  LEU C CA  1 
ATOM   7152 C  C   . LEU D 2 71  ? -28.697 5.777   23.149  1   47.33  ? 67  LEU C C   1 
ATOM   7153 O  O   . LEU D 2 71  ? -28.275 4.969   22.303  1   47.53  ? 67  LEU C O   1 
ATOM   7154 C  CB  . LEU D 2 71  ? -28.811 8.106   22.202  1   46.29  ? 67  LEU C CB  1 
ATOM   7155 C  CG  . LEU D 2 71  ? -29.546 9.444   22.115  1   45.39  ? 67  LEU C CG  1 
ATOM   7156 C  CD1 . LEU D 2 71  ? -28.49  10.528  22.111  1   45.01  ? 67  LEU C CD1 1 
ATOM   7157 C  CD2 . LEU D 2 71  ? -30.345 9.495   20.833  1   45.98  ? 67  LEU C CD2 1 
ATOM   7158 N  N   . ASP D 2 72  ? -28.442 5.702   24.455  1   47.79  ? 68  ASP C N   1 
ATOM   7159 C  CA  . ASP D 2 72  ? -27.459 4.746   24.943  1   49.01  ? 68  ASP C CA  1 
ATOM   7160 C  C   . ASP D 2 72  ? -27.547 4.606   26.458  1   47.89  ? 68  ASP C C   1 
ATOM   7161 O  O   . ASP D 2 72  ? -28.085 5.463   27.158  1   48.72  ? 68  ASP C O   1 
ATOM   7162 C  CB  . ASP D 2 72  ? -26.059 5.095   24.452  1   50.47  ? 68  ASP C CB  1 
ATOM   7163 C  CG  . ASP D 2 72  ? -25.052 3.959   24.379  1   51.4   ? 68  ASP C CG  1 
ATOM   7164 O  OD1 . ASP D 2 72  ? -25.354 2.847   24.845  1   53.57  ? 68  ASP C OD1 1 
ATOM   7165 O  OD2 . ASP D 2 72  ? -23.967 4.19    23.843  1   54.14  ? 68  ASP C OD2 1 
ATOM   7166 N  N   . VAL D 2 73  ? -27.041 3.472   26.935  1   49.25  ? 69  VAL C N   1 
ATOM   7167 C  CA  . VAL D 2 73  ? -26.855 3.201   28.35   1   48.61  ? 69  VAL C CA  1 
ATOM   7168 C  C   . VAL D 2 73  ? -25.44  2.657   28.521  1   50.84  ? 69  VAL C C   1 
ATOM   7169 O  O   . VAL D 2 73  ? -25.112 1.602   27.976  1   50.27  ? 69  VAL C O   1 
ATOM   7170 C  CB  . VAL D 2 73  ? -27.895 2.219   28.915  1   46.43  ? 69  VAL C CB  1 
ATOM   7171 C  CG1 . VAL D 2 73  ? -27.77  2.112   30.429  1   46.17  ? 69  VAL C CG1 1 
ATOM   7172 C  CG2 . VAL D 2 73  ? -29.323 2.603   28.508  1   46.39  ? 69  VAL C CG2 1 
ATOM   7173 N  N   . ILE D 2 74  ? -24.613 3.436   29.239  1   53.14  ? 70  ILE C N   1 
ATOM   7174 C  CA  . ILE D 2 74  ? -23.197 3.171   29.427  1   56.14  ? 70  ILE C CA  1 
ATOM   7175 C  C   . ILE D 2 74  ? -23.033 2.69    30.855  1   57.03  ? 70  ILE C C   1 
ATOM   7176 O  O   . ILE D 2 74  ? -23.41  3.396   31.783  1   57.15  ? 70  ILE C O   1 
ATOM   7177 C  CB  . ILE D 2 74  ? -22.331 4.402   29.071  1   55.59  ? 70  ILE C CB  1 
ATOM   7178 C  CG1 . ILE D 2 74  ? -22.619 4.841   27.648  1   55.6   ? 70  ILE C CG1 1 
ATOM   7179 C  CG2 . ILE D 2 74  ? -20.838 4.129   29.248  1   51.13  ? 70  ILE C CG2 1 
ATOM   7180 C  CD1 . ILE D 2 74  ? -21.837 6.06    27.217  1   62.41  ? 70  ILE C CD1 1 
ATOM   7181 N  N   . HIS D 2 75  ? -22.511 1.465   30.979  1   62.1   ? 71  HIS C N   1 
ATOM   7182 C  CA  . HIS D 2 75  ? -22.442 0.77    32.258  1   67.95  ? 71  HIS C CA  1 
ATOM   7183 C  C   . HIS D 2 75  ? -21.03  0.919   32.809  1   67.53  ? 71  HIS C C   1 
ATOM   7184 O  O   . HIS D 2 75  ? -20.086 1.003   32.041  1   71.32  ? 71  HIS C O   1 
ATOM   7185 C  CB  . HIS D 2 75  ? -22.675 -0.742  32.086  1   69.14  ? 71  HIS C CB  1 
ATOM   7186 C  CG  . HIS D 2 75  ? -24.058 -1.162  31.725  1   63.02  ? 71  HIS C CG  1 
ATOM   7187 N  ND1 . HIS D 2 75  ? -24.912 -1.756  32.631  1   61.88  ? 71  HIS C ND1 1 
ATOM   7188 C  CD2 . HIS D 2 75  ? -24.709 -1.094  30.548  1   61.05  ? 71  HIS C CD2 1 
ATOM   7189 C  CE1 . HIS D 2 75  ? -26.059 -2.016  32.02   1   65.08  ? 71  HIS C CE1 1 
ATOM   7190 N  NE2 . HIS D 2 75  ? -25.966 -1.603  30.753  1   65.64  ? 71  HIS C NE2 1 
ATOM   7191 N  N   . THR D 2 76  ? -20.898 0.981   34.132  1   67.76  ? 72  THR C N   1 
ATOM   7192 C  CA  . THR D 2 76  ? -19.618 0.755   34.784  1   69.86  ? 72  THR C CA  1 
ATOM   7193 C  C   . THR D 2 76  ? -19.919 -0.262  35.886  1   71.32  ? 72  THR C C   1 
ATOM   7194 O  O   . THR D 2 76  ? -21.016 -0.844  35.874  1   65.18  ? 72  THR C O   1 
ATOM   7195 C  CB  . THR D 2 76  ? -18.905 2.051   35.23   1   70.75  ? 72  THR C CB  1 
ATOM   7196 O  OG1 . THR D 2 76  ? -19.621 2.755   36.241  1   77.18  ? 72  THR C OG1 1 
ATOM   7197 C  CG2 . THR D 2 76  ? -18.636 3.071   34.131  1   66.73  ? 72  THR C CG2 1 
ATOM   7198 N  N   . GLU D 2 77  ? -18.943 -0.508  36.777  1   77.64  ? 73  GLU C N   1 
ATOM   7199 C  CA  . GLU D 2 77  ? -19.188 -1.231  38.017  1   79.4   ? 73  GLU C CA  1 
ATOM   7200 C  C   . GLU D 2 77  ? -20.111 -0.423  38.928  1   77.34  ? 73  GLU C C   1 
ATOM   7201 O  O   . GLU D 2 77  ? -21.046 -0.992  39.486  1   77.16  ? 73  GLU C O   1 
ATOM   7202 C  CB  . GLU D 2 77  ? -17.902 -1.603  38.755  1   92.94  ? 73  GLU C CB  1 
ATOM   7203 C  CG  . GLU D 2 77  ? -17.117 -2.72   38.073  1   108.14 ? 73  GLU C CG  1 
ATOM   7204 C  CD  . GLU D 2 77  ? -17.887 -4.023  37.906  1   120.14 ? 73  GLU C CD  1 
ATOM   7205 O  OE1 . GLU D 2 77  ? -18.358 -4.285  36.772  1   112.57 ? 73  GLU C OE1 1 
ATOM   7206 O  OE2 . GLU D 2 77  ? -17.981 -4.8    38.892  1   130.16 ? 73  GLU C OE2 1 
ATOM   7207 N  N   . ASN D 2 78  ? -19.87  0.899   39.033  1   77.7   ? 74  ASN C N   1 
ATOM   7208 C  CA  . ASN D 2 78  ? -20.401 1.731   40.108  1   73.83  ? 74  ASN C CA  1 
ATOM   7209 C  C   . ASN D 2 78  ? -21.423 2.762   39.616  1   73.49  ? 74  ASN C C   1 
ATOM   7210 O  O   . ASN D 2 78  ? -22.215 3.266   40.417  1   73.86  ? 74  ASN C O   1 
ATOM   7211 C  CB  . ASN D 2 78  ? -19.272 2.357   40.916  1   76.75  ? 74  ASN C CB  1 
ATOM   7212 C  CG  . ASN D 2 78  ? -18.636 1.362   41.864  1   82.44  ? 74  ASN C CG  1 
ATOM   7213 O  OD1 . ASN D 2 78  ? -19.096 1.171   43.004  1   86.53  ? 74  ASN C OD1 1 
ATOM   7214 N  ND2 . ASN D 2 78  ? -17.567 0.727   41.407  1   79.41  ? 74  ASN C ND2 1 
ATOM   7215 N  N   . LYS D 2 79  ? -21.41  3.09    38.314  1   68.83  ? 75  LYS C N   1 
ATOM   7216 C  CA  . LYS D 2 79  ? -22.269 4.149   37.808  1   61.06  ? 75  LYS C CA  1 
ATOM   7217 C  C   . LYS D 2 79  ? -23.035 3.654   36.595  1   57.15  ? 75  LYS C C   1 
ATOM   7218 O  O   . LYS D 2 79  ? -22.621 2.741   35.898  1   61.54  ? 75  LYS C O   1 
ATOM   7219 C  CB  . LYS D 2 79  ? -21.432 5.374   37.43   1   63.1   ? 75  LYS C CB  1 
ATOM   7220 C  CG  . LYS D 2 79  ? -21.033 6.265   38.589  1   71.59  ? 75  LYS C CG  1 
ATOM   7221 C  CD  . LYS D 2 79  ? -19.646 6.896   38.465  1   80.66  ? 75  LYS C CD  1 
ATOM   7222 C  CE  . LYS D 2 79  ? -19.305 7.758   39.653  1   86.16  ? 75  LYS C CE  1 
ATOM   7223 N  NZ  . LYS D 2 79  ? -17.912 8.224   39.65   1   84.99  ? 75  LYS C NZ  1 
ATOM   7224 N  N   . LEU D 2 80  ? -24.162 4.292   36.338  1   53     ? 76  LEU C N   1 
ATOM   7225 C  CA  . LEU D 2 80  ? -24.879 4.083   35.098  1   51.14  ? 76  LEU C CA  1 
ATOM   7226 C  C   . LEU D 2 80  ? -25.072 5.459   34.443  1   52.96  ? 76  LEU C C   1 
ATOM   7227 O  O   . LEU D 2 80  ? -25.538 6.399   35.093  1   54.97  ? 76  LEU C O   1 
ATOM   7228 C  CB  . LEU D 2 80  ? -26.187 3.452   35.578  1   48.36  ? 76  LEU C CB  1 
ATOM   7229 C  CG  . LEU D 2 80  ? -26.916 2.53    34.604  1   48.7   ? 76  LEU C CG  1 
ATOM   7230 C  CD1 . LEU D 2 80  ? -25.992 1.404   34.146  1   51.99  ? 76  LEU C CD1 1 
ATOM   7231 C  CD2 . LEU D 2 80  ? -28.107 1.966   35.34   1   46.24  ? 76  LEU C CD2 1 
ATOM   7232 N  N   . TYR D 2 81  ? -24.665 5.619   33.179  1   50.06  ? 77  TYR C N   1 
ATOM   7233 C  CA  . TYR D 2 81  ? -25.006 6.851   32.485  1   49.44  ? 77  TYR C CA  1 
ATOM   7234 C  C   . TYR D 2 81  ? -26.081 6.572   31.432  1   49.71  ? 77  TYR C C   1 
ATOM   7235 O  O   . TYR D 2 81  ? -25.925 5.673   30.609  1   51.75  ? 77  TYR C O   1 
ATOM   7236 C  CB  . TYR D 2 81  ? -23.783 7.485   31.83   1   51.3   ? 77  TYR C CB  1 
ATOM   7237 C  CG  . TYR D 2 81  ? -22.7   7.922   32.797  1   53.75  ? 77  TYR C CG  1 
ATOM   7238 C  CD1 . TYR D 2 81  ? -21.809 7.006   33.337  1   55     ? 77  TYR C CD1 1 
ATOM   7239 C  CD2 . TYR D 2 81  ? -22.559 9.26    33.14   1   55.85  ? 77  TYR C CD2 1 
ATOM   7240 C  CE1 . TYR D 2 81  ? -20.812 7.404   34.217  1   60.39  ? 77  TYR C CE1 1 
ATOM   7241 C  CE2 . TYR D 2 81  ? -21.56  9.674   34.003  1   60.88  ? 77  TYR C CE2 1 
ATOM   7242 C  CZ  . TYR D 2 81  ? -20.676 8.749   34.547  1   66.9   ? 77  TYR C CZ  1 
ATOM   7243 O  OH  . TYR D 2 81  ? -19.675 9.179   35.407  1   73.39  ? 77  TYR C OH  1 
ATOM   7244 N  N   . LEU D 2 82  ? -27.184 7.33    31.483  1   45.75  ? 78  LEU C N   1 
ATOM   7245 C  CA  . LEU D 2 82  ? -28.136 7.318   30.399  1   46.26  ? 78  LEU C CA  1 
ATOM   7246 C  C   . LEU D 2 82  ? -27.776 8.463   29.464  1   47.03  ? 78  LEU C C   1 
ATOM   7247 O  O   . LEU D 2 82  ? -27.539 9.568   29.928  1   45.62  ? 78  LEU C O   1 
ATOM   7248 C  CB  . LEU D 2 82  ? -29.566 7.474   30.917  1   52.44  ? 78  LEU C CB  1 
ATOM   7249 C  CG  . LEU D 2 82  ? -29.981 6.677   32.16   1   53.05  ? 78  LEU C CG  1 
ATOM   7250 C  CD1 . LEU D 2 82  ? -31.489 6.685   32.252  1   53.38  ? 78  LEU C CD1 1 
ATOM   7251 C  CD2 . LEU D 2 82  ? -29.492 5.267   32.124  1   59     ? 78  LEU C CD2 1 
ATOM   7252 N  N   . VAL D 2 83  ? -27.716 8.163   28.163  1   47.36  ? 79  VAL C N   1 
ATOM   7253 C  CA  . VAL D 2 83  ? -27.404 9.133   27.135  1   46.19  ? 79  VAL C CA  1 
ATOM   7254 C  C   . VAL D 2 83  ? -28.721 9.486   26.452  1   47.86  ? 79  VAL C C   1 
ATOM   7255 O  O   . VAL D 2 83  ? -29.405 8.592   25.923  1   45.09  ? 79  VAL C O   1 
ATOM   7256 C  CB  . VAL D 2 83  ? -26.349 8.616   26.133  1   44.61  ? 79  VAL C CB  1 
ATOM   7257 C  CG1 . VAL D 2 83  ? -25.821 9.738   25.247  1   43.49  ? 79  VAL C CG1 1 
ATOM   7258 C  CG2 . VAL D 2 83  ? -25.188 7.957   26.854  1   43.3   ? 79  VAL C CG2 1 
ATOM   7259 N  N   . PHE D 2 84  ? -29.057 10.791  26.504  1   46     ? 80  PHE C N   1 
ATOM   7260 C  CA  . PHE D 2 84  ? -30.31  11.303  25.963  1   46.89  ? 80  PHE C CA  1 
ATOM   7261 C  C   . PHE D 2 84  ? -29.987 12.325  24.888  1   46.23  ? 80  PHE C C   1 
ATOM   7262 O  O   . PHE D 2 84  ? -29.028 13.071  25.045  1   47.84  ? 80  PHE C O   1 
ATOM   7263 C  CB  . PHE D 2 84  ? -31.111 12.043  27.048  1   48     ? 80  PHE C CB  1 
ATOM   7264 C  CG  . PHE D 2 84  ? -31.906 11.152  27.983  1   45.85  ? 80  PHE C CG  1 
ATOM   7265 C  CD1 . PHE D 2 84  ? -33.116 10.606  27.562  1   48.56  ? 80  PHE C CD1 1 
ATOM   7266 C  CD2 . PHE D 2 84  ? -31.421 10.825  29.242  1   45.75  ? 80  PHE C CD2 1 
ATOM   7267 C  CE1 . PHE D 2 84  ? -33.823 9.74    28.376  1   47.25  ? 80  PHE C CE1 1 
ATOM   7268 C  CE2 . PHE D 2 84  ? -32.134 9.962   30.058  1   44     ? 80  PHE C CE2 1 
ATOM   7269 C  CZ  . PHE D 2 84  ? -33.338 9.444   29.642  1   45.13  ? 80  PHE C CZ  1 
ATOM   7270 N  N   . GLU D 2 85  ? -30.917 12.505  23.961  1   46.45  ? 81  GLU C N   1 
ATOM   7271 C  CA  . GLU D 2 85  ? -30.767 13.608  22.992  1   49.97  ? 81  GLU C CA  1 
ATOM   7272 C  C   . GLU D 2 85  ? -30.948 14.913  23.771  1   49.34  ? 81  GLU C C   1 
ATOM   7273 O  O   . GLU D 2 85  ? -31.739 14.927  24.724  1   49.64  ? 81  GLU C O   1 
ATOM   7274 C  CB  . GLU D 2 85  ? -31.866 13.505  21.946  1   52.41  ? 81  GLU C CB  1 
ATOM   7275 C  CG  . GLU D 2 85  ? -33.229 13.184  22.547  1   61.17  ? 81  GLU C CG  1 
ATOM   7276 C  CD  . GLU D 2 85  ? -34.411 13.605  21.699  1   68.06  ? 81  GLU C CD  1 
ATOM   7277 O  OE1 . GLU D 2 85  ? -34.214 14.376  20.741  1   68.87  ? 81  GLU C OE1 1 
ATOM   7278 O  OE2 . GLU D 2 85  ? -35.531 13.157  22.003  1   66.65  ? 81  GLU C OE2 1 
ATOM   7279 N  N   . PHE D 2 86  ? -30.238 15.966  23.381  1   48.26  ? 82  PHE C N   1 
ATOM   7280 C  CA  . PHE D 2 86  ? -30.328 17.241  24.131  1   50.07  ? 82  PHE C CA  1 
ATOM   7281 C  C   . PHE D 2 86  ? -31.488 18.057  23.606  1   52.32  ? 82  PHE C C   1 
ATOM   7282 O  O   . PHE D 2 86  ? -31.677 18.129  22.386  1   53.76  ? 82  PHE C O   1 
ATOM   7283 C  CB  . PHE D 2 86  ? -29.054 18.083  24.066  1   50.46  ? 82  PHE C CB  1 
ATOM   7284 C  CG  . PHE D 2 86  ? -29.123 19.387  24.843  1   51.7   ? 82  PHE C CG  1 
ATOM   7285 C  CD1 . PHE D 2 86  ? -29.039 19.391  26.227  1   51.44  ? 82  PHE C CD1 1 
ATOM   7286 C  CD2 . PHE D 2 86  ? -29.276 20.6    24.185  1   55.42  ? 82  PHE C CD2 1 
ATOM   7287 C  CE1 . PHE D 2 86  ? -29.108 20.579  26.932  1   54.9   ? 82  PHE C CE1 1 
ATOM   7288 C  CE2 . PHE D 2 86  ? -29.343 21.784  24.895  1   55.72  ? 82  PHE C CE2 1 
ATOM   7289 C  CZ  . PHE D 2 86  ? -29.26  21.769  26.265  1   56.13  ? 82  PHE C CZ  1 
ATOM   7290 N  N   . LEU D 2 87  ? -32.265 18.635  24.518  1   58.86  ? 83  LEU C N   1 
ATOM   7291 C  CA  . LEU D 2 87  ? -33.367 19.541  24.127  1   55.19  ? 83  LEU C CA  1 
ATOM   7292 C  C   . LEU D 2 87  ? -33.115 20.87   24.852  1   54.17  ? 83  LEU C C   1 
ATOM   7293 O  O   . LEU D 2 87  ? -32.807 20.825  26.051  1   52.07  ? 83  LEU C O   1 
ATOM   7294 C  CB  . LEU D 2 87  ? -34.723 18.912  24.426  1   54.05  ? 83  LEU C CB  1 
ATOM   7295 C  CG  . LEU D 2 87  ? -35.055 17.654  23.619  1   56.79  ? 83  LEU C CG  1 
ATOM   7296 C  CD1 . LEU D 2 87  ? -36.351 17.03   24.096  1   58.87  ? 83  LEU C CD1 1 
ATOM   7297 C  CD2 . LEU D 2 87  ? -35.112 17.945  22.134  1   57.15  ? 83  LEU C CD2 1 
ATOM   7298 N  N   . HIS D 2 88  ? -33.222 21.993  24.146  1   57.37  ? 84  HIS C N   1 
ATOM   7299 C  CA  . HIS D 2 88  ? -32.876 23.335  24.698  1   60.92  ? 84  HIS C CA  1 
ATOM   7300 C  C   . HIS D 2 88  ? -33.406 23.577  26.111  1   58.95  ? 84  HIS C C   1 
ATOM   7301 O  O   . HIS D 2 88  ? -32.597 23.991  26.956  1   58.65  ? 84  HIS C O   1 
ATOM   7302 C  CB  . HIS D 2 88  ? -33.389 24.433  23.766  1   62.1   ? 84  HIS C CB  1 
ATOM   7303 C  CG  . HIS D 2 88  ? -33.011 25.808  24.193  1   64.69  ? 84  HIS C CG  1 
ATOM   7304 N  ND1 . HIS D 2 88  ? -33.924 26.709  24.693  1   66.61  ? 84  HIS C ND1 1 
ATOM   7305 C  CD2 . HIS D 2 88  ? -31.831 26.431  24.202  1   67.98  ? 84  HIS C CD2 1 
ATOM   7306 C  CE1 . HIS D 2 88  ? -33.302 27.839  24.988  1   68.06  ? 84  HIS C CE1 1 
ATOM   7307 N  NE2 . HIS D 2 88  ? -32.03  27.692  24.698  1   68.81  ? 84  HIS C NE2 1 
ATOM   7308 N  N   . GLN D 2 89  ? -34.702 23.382  26.349  1   57.26  ? 85  GLN C N   1 
ATOM   7309 C  CA  . GLN D 2 89  ? -35.178 23.555  27.738  1   57.04  ? 85  GLN C CA  1 
ATOM   7310 C  C   . GLN D 2 89  ? -36.519 22.885  28.011  1   55.25  ? 85  GLN C C   1 
ATOM   7311 O  O   . GLN D 2 89  ? -37.064 22.23   27.115  1   53.72  ? 85  GLN C O   1 
ATOM   7312 C  CB  . GLN D 2 89  ? -35.364 25.031  28.083  1   59.14  ? 85  GLN C CB  1 
ATOM   7313 C  CG  . GLN D 2 89  ? -36.346 25.779  27.191  1   64.25  ? 85  GLN C CG  1 
ATOM   7314 C  CD  . GLN D 2 89  ? -36.446 27.245  27.546  1   68.3   ? 85  GLN C CD  1 
ATOM   7315 O  OE1 . GLN D 2 89  ? -35.829 27.717  28.506  1   66     ? 85  GLN C OE1 1 
ATOM   7316 N  NE2 . GLN D 2 89  ? -37.224 27.983  26.769  1   70.41  ? 85  GLN C NE2 1 
ATOM   7317 N  N   . ASP D 2 90  ? -37.005 23.058  29.232  1   53.8   ? 86  ASP C N   1 
ATOM   7318 C  CA  . ASP D 2 90  ? -38.279 22.515  29.664  1   53.16  ? 86  ASP C CA  1 
ATOM   7319 C  C   . ASP D 2 90  ? -39.357 23.603  29.608  1   57.08  ? 86  ASP C C   1 
ATOM   7320 O  O   . ASP D 2 90  ? -39.077 24.811  29.694  1   56.27  ? 86  ASP C O   1 
ATOM   7321 C  CB  . ASP D 2 90  ? -38.181 21.981  31.08   1   52.3   ? 86  ASP C CB  1 
ATOM   7322 C  CG  . ASP D 2 90  ? -37.898 23.057  32.112  1   56.15  ? 86  ASP C CG  1 
ATOM   7323 O  OD1 . ASP D 2 90  ? -38.791 23.878  32.399  1   55.61  ? 86  ASP C OD1 1 
ATOM   7324 O  OD2 . ASP D 2 90  ? -36.764 23.091  32.583  1   64.66  ? 86  ASP C OD2 1 
ATOM   7325 N  N   . LEU D 2 91  ? -40.613 23.13   29.535  1   55.23  ? 87  LEU C N   1 
ATOM   7326 C  CA  . LEU D 2 91  ? -41.76  23.972  29.261  1   54.02  ? 87  LEU C CA  1 
ATOM   7327 C  C   . LEU D 2 91  ? -41.903 25.004  30.376  1   56.43  ? 87  LEU C C   1 
ATOM   7328 O  O   . LEU D 2 91  ? -42.313 26.125  30.112  1   57.99  ? 87  LEU C O   1 
ATOM   7329 C  CB  . LEU D 2 91  ? -42.994 23.082  29.111  1   51.41  ? 87  LEU C CB  1 
ATOM   7330 C  CG  . LEU D 2 91  ? -44.312 23.789  28.759  1   50.88  ? 87  LEU C CG  1 
ATOM   7331 C  CD1 . LEU D 2 91  ? -44.252 24.598  27.473  1   50.03  ? 87  LEU C CD1 1 
ATOM   7332 C  CD2 . LEU D 2 91  ? -45.452 22.79   28.668  1   48.19  ? 87  LEU C CD2 1 
ATOM   7333 N  N   . LYS D 2 92  ? -41.517 24.63   31.601  1   54.62  ? 88  LYS C N   1 
ATOM   7334 C  CA  . LYS D 2 92  ? -41.684 25.489  32.761  1   53     ? 88  LYS C CA  1 
ATOM   7335 C  C   . LYS D 2 92  ? -40.761 26.694  32.633  1   52.78  ? 88  LYS C C   1 
ATOM   7336 O  O   . LYS D 2 92  ? -41.147 27.809  32.96   1   56.71  ? 88  LYS C O   1 
ATOM   7337 C  CB  . LYS D 2 92  ? -41.524 24.707  34.071  1   50.53  ? 88  LYS C CB  1 
ATOM   7338 C  CG  . LYS D 2 92  ? -41.453 25.535  35.339  1   54.99  ? 88  LYS C CG  1 
ATOM   7339 C  CD  . LYS D 2 92  ? -42.504 26.604  35.644  1   59.77  ? 88  LYS C CD  1 
ATOM   7340 C  CE  . LYS D 2 92  ? -43.852 26.021  35.927  1   66.51  ? 88  LYS C CE  1 
ATOM   7341 N  NZ  . LYS D 2 92  ? -44.769 26.953  36.595  1   68.23  ? 88  LYS C NZ  1 
ATOM   7342 N  N   . LYS D 2 93  ? -39.548 26.483  32.134  1   53.22  ? 89  LYS C N   1 
ATOM   7343 C  CA  . LYS D 2 93  ? -38.631 27.606  32.009  1   55.33  ? 89  LYS C CA  1 
ATOM   7344 C  C   . LYS D 2 93  ? -39.114 28.561  30.92   1   53.64  ? 89  LYS C C   1 
ATOM   7345 O  O   . LYS D 2 93  ? -38.932 29.783  31.032  1   51.96  ? 89  LYS C O   1 
ATOM   7346 C  CB  . LYS D 2 93  ? -37.22  27.094  31.72   1   57.74  ? 89  LYS C CB  1 
ATOM   7347 C  CG  . LYS D 2 93  ? -36.458 26.69   32.972  1   65.17  ? 89  LYS C CG  1 
ATOM   7348 C  CD  . LYS D 2 93  ? -35.012 26.304  32.662  1   76.59  ? 89  LYS C CD  1 
ATOM   7349 C  CE  . LYS D 2 93  ? -34.196 26.058  33.901  1   82.36  ? 89  LYS C CE  1 
ATOM   7350 N  NZ  . LYS D 2 93  ? -34.766 24.934  34.651  1   82.83  ? 89  LYS C NZ  1 
ATOM   7351 N  N   . PHE D 2 94  ? -39.714 27.955  29.884  1   52.86  ? 90  PHE C N   1 
ATOM   7352 C  CA  . PHE D 2 94  ? -40.246 28.631  28.714  1   56.75  ? 90  PHE C CA  1 
ATOM   7353 C  C   . PHE D 2 94  ? -41.466 29.453  29.114  1   61.22  ? 90  PHE C C   1 
ATOM   7354 O  O   . PHE D 2 94  ? -41.575 30.635  28.753  1   66.47  ? 90  PHE C O   1 
ATOM   7355 C  CB  . PHE D 2 94  ? -40.615 27.625  27.617  1   57.5   ? 90  PHE C CB  1 
ATOM   7356 C  CG  . PHE D 2 94  ? -41.201 28.267  26.365  1   60.82  ? 90  PHE C CG  1 
ATOM   7357 C  CD1 . PHE D 2 94  ? -40.44  29.147  25.598  1   63.51  ? 90  PHE C CD1 1 
ATOM   7358 C  CD2 . PHE D 2 94  ? -42.513 28.012  25.966  1   60.73  ? 90  PHE C CD2 1 
ATOM   7359 C  CE1 . PHE D 2 94  ? -40.976 29.733  24.46   1   63.9   ? 90  PHE C CE1 1 
ATOM   7360 C  CE2 . PHE D 2 94  ? -43.045 28.602  24.827  1   60.38  ? 90  PHE C CE2 1 
ATOM   7361 C  CZ  . PHE D 2 94  ? -42.272 29.455  24.073  1   62.88  ? 90  PHE C CZ  1 
ATOM   7362 N  N   . MET D 2 95  ? -42.374 28.81   29.862  1   56.34  ? 91  MET C N   1 
ATOM   7363 C  CA  . MET D 2 95  ? -43.52  29.512  30.399  1   55.9   ? 91  MET C CA  1 
ATOM   7364 C  C   . MET D 2 95  ? -43.015 30.733  31.16   1   60.07  ? 91  MET C C   1 
ATOM   7365 O  O   . MET D 2 95  ? -43.444 31.843  30.862  1   66.8   ? 91  MET C O   1 
ATOM   7366 C  CB  . MET D 2 95  ? -44.426 28.582  31.211  1   54.13  ? 91  MET C CB  1 
ATOM   7367 C  CG  . MET D 2 95  ? -45.37  27.757  30.347  1   56.73  ? 91  MET C CG  1 
ATOM   7368 S  SD  . MET D 2 95  ? -46.331 26.456  31.159  1   65.52  ? 91  MET C SD  1 
ATOM   7369 C  CE  . MET D 2 95  ? -45.194 25.819  32.388  1   56.64  ? 91  MET C CE  1 
ATOM   7370 N  N   . ASP D 2 96  ? -42.064 30.531  32.089  1   59.9   ? 92  ASP C N   1 
ATOM   7371 C  CA  . ASP D 2 96  ? -41.542 31.589  32.944  1   60.43  ? 92  ASP C CA  1 
ATOM   7372 C  C   . ASP D 2 96  ? -40.943 32.7    32.089  1   62.63  ? 92  ASP C C   1 
ATOM   7373 O  O   . ASP D 2 96  ? -41.207 33.877  32.321  1   62.2   ? 92  ASP C O   1 
ATOM   7374 C  CB  . ASP D 2 96  ? -40.585 31.052  33.995  1   61.33  ? 92  ASP C CB  1 
ATOM   7375 C  CG  . ASP D 2 96  ? -41.264 30.29   35.124  1   64.93  ? 92  ASP C CG  1 
ATOM   7376 O  OD1 . ASP D 2 96  ? -42.509 30.364  35.191  1   65.11  ? 92  ASP C OD1 1 
ATOM   7377 O  OD2 . ASP D 2 96  ? -40.558 29.602  35.917  1   67.38  ? 92  ASP C OD2 1 
ATOM   7378 N  N   . ALA D 2 97  ? -40.156 32.315  31.079  1   63.56  ? 93  ALA C N   1 
ATOM   7379 C  CA  . ALA D 2 97  ? -39.572 33.292  30.177  1   64.46  ? 93  ALA C CA  1 
ATOM   7380 C  C   . ALA D 2 97  ? -40.673 34.093  29.482  1   66.5   ? 93  ALA C C   1 
ATOM   7381 O  O   . ALA D 2 97  ? -40.419 35.21   29.045  1   72.29  ? 93  ALA C O   1 
ATOM   7382 C  CB  . ALA D 2 97  ? -38.686 32.6    29.169  1   63.01  ? 93  ALA C CB  1 
ATOM   7383 N  N   . SER D 2 98  ? -41.885 33.524  29.384  1   64.57  ? 94  SER C N   1 
ATOM   7384 C  CA  . SER D 2 98  ? -42.965 34.064  28.573  1   64.98  ? 94  SER C CA  1 
ATOM   7385 C  C   . SER D 2 98  ? -44.091 34.641  29.427  1   67.17  ? 94  SER C C   1 
ATOM   7386 O  O   . SER D 2 98  ? -45.158 34.938  28.898  1   70.11  ? 94  SER C O   1 
ATOM   7387 C  CB  . SER D 2 98  ? -43.528 33.027  27.631  1   64.18  ? 94  SER C CB  1 
ATOM   7388 O  OG  . SER D 2 98  ? -42.545 32.609  26.702  1   67.85  ? 94  SER C OG  1 
ATOM   7389 N  N   . ALA D 2 99  ? -43.866 34.835  30.729  1   67.93  ? 95  ALA C N   1 
ATOM   7390 C  CA  . ALA D 2 99  ? -44.925 35.316  31.613  1   69.45  ? 95  ALA C CA  1 
ATOM   7391 C  C   . ALA D 2 99  ? -45.408 36.729  31.257  1   71.61  ? 95  ALA C C   1 
ATOM   7392 O  O   . ALA D 2 99  ? -46.575 37.044  31.527  1   71.12  ? 95  ALA C O   1 
ATOM   7393 C  CB  . ALA D 2 99  ? -44.498 35.208  33.059  1   70.92  ? 95  ALA C CB  1 
ATOM   7394 N  N   . LEU D 2 100 ? -44.544 37.555  30.636  1   69.61  ? 96  LEU C N   1 
ATOM   7395 C  CA  . LEU D 2 100 ? -44.955 38.903  30.269  1   70.48  ? 96  LEU C CA  1 
ATOM   7396 C  C   . LEU D 2 100 ? -45.437 38.987  28.816  1   73.71  ? 96  LEU C C   1 
ATOM   7397 O  O   . LEU D 2 100 ? -46.456 39.631  28.558  1   79.1   ? 96  LEU C O   1 
ATOM   7398 C  CB  . LEU D 2 100 ? -43.914 39.964  30.611  1   68.25  ? 96  LEU C CB  1 
ATOM   7399 C  CG  . LEU D 2 100 ? -43.467 39.952  32.071  1   67.27  ? 96  LEU C CG  1 
ATOM   7400 C  CD1 . LEU D 2 100 ? -42.551 41.102  32.383  1   68.92  ? 96  LEU C CD1 1 
ATOM   7401 C  CD2 . LEU D 2 100 ? -44.633 39.917  33.036  1   66.81  ? 96  LEU C CD2 1 
ATOM   7402 N  N   . THR D 2 101 ? -44.72  38.351  27.875  1   71.95  ? 97  THR C N   1 
ATOM   7403 C  CA  . THR D 2 101 ? -45.073 38.405  26.454  1   73.8   ? 97  THR C CA  1 
ATOM   7404 C  C   . THR D 2 101 ? -46.297 37.543  26.156  1   71.79  ? 97  THR C C   1 
ATOM   7405 O  O   . THR D 2 101 ? -47.05  37.832  25.227  1   73.53  ? 97  THR C O   1 
ATOM   7406 C  CB  . THR D 2 101 ? -43.958 37.95   25.506  1   73.58  ? 97  THR C CB  1 
ATOM   7407 O  OG1 . THR D 2 101 ? -43.824 36.544  25.719  1   72.27  ? 97  THR C OG1 1 
ATOM   7408 C  CG2 . THR D 2 101 ? -42.67  38.734  25.653  1   74.01  ? 97  THR C CG2 1 
ATOM   7409 N  N   . GLY D 2 102 ? -46.441 36.434  26.886  1   68.58  ? 98  GLY C N   1 
ATOM   7410 C  CA  . GLY D 2 102 ? -47.359 35.382  26.489  1   67.41  ? 98  GLY C CA  1 
ATOM   7411 C  C   . GLY D 2 102 ? -46.715 34.434  25.481  1   66.61  ? 98  GLY C C   1 
ATOM   7412 O  O   . GLY D 2 102 ? -45.724 34.779  24.833  1   65.04  ? 98  GLY C O   1 
ATOM   7413 N  N   . ILE D 2 103 ? -47.297 33.228  25.409  1   67.02  ? 99  ILE C N   1 
ATOM   7414 C  CA  . ILE D 2 103 ? -47.061 32.23   24.369  1   67.53  ? 99  ILE C CA  1 
ATOM   7415 C  C   . ILE D 2 103 ? -48.154 32.356  23.303  1   67.66  ? 99  ILE C C   1 
ATOM   7416 O  O   . ILE D 2 103 ? -49.339 32.212  23.585  1   69.2   ? 99  ILE C O   1 
ATOM   7417 C  CB  . ILE D 2 103 ? -47.093 30.802  24.95   1   63.77  ? 99  ILE C CB  1 
ATOM   7418 C  CG1 . ILE D 2 103 ? -46.212 30.645  26.184  1   63.85  ? 99  ILE C CG1 1 
ATOM   7419 C  CG2 . ILE D 2 103 ? -46.774 29.769  23.874  1   62.49  ? 99  ILE C CG2 1 
ATOM   7420 C  CD1 . ILE D 2 103 ? -46.241 29.248  26.786  1   62.07  ? 99  ILE C CD1 1 
ATOM   7421 N  N   . PRO D 2 104 ? -47.814 32.545  22.018  1   68.09  ? 100 PRO C N   1 
ATOM   7422 C  CA  . PRO D 2 104 ? -48.847 32.558  20.981  1   69.49  ? 100 PRO C CA  1 
ATOM   7423 C  C   . PRO D 2 104 ? -49.715 31.297  20.903  1   70.82  ? 100 PRO C C   1 
ATOM   7424 O  O   . PRO D 2 104 ? -49.233 30.177  21.08   1   70.09  ? 100 PRO C O   1 
ATOM   7425 C  CB  . PRO D 2 104 ? -48.016 32.779  19.698  1   71.46  ? 100 PRO C CB  1 
ATOM   7426 C  CG  . PRO D 2 104 ? -46.702 33.375  20.158  1   69.97  ? 100 PRO C CG  1 
ATOM   7427 C  CD  . PRO D 2 104 ? -46.442 32.746  21.515  1   67.84  ? 100 PRO C CD  1 
ATOM   7428 N  N   . LEU D 2 105 ? -51     31.496  20.585  1   76.13  ? 101 LEU C N   1 
ATOM   7429 C  CA  . LEU D 2 105 ? -52.021 30.457  20.496  1   80.18  ? 101 LEU C CA  1 
ATOM   7430 C  C   . LEU D 2 105 ? -51.628 29.361  19.49   1   78.53  ? 101 LEU C C   1 
ATOM   7431 O  O   . LEU D 2 105 ? -51.725 28.179  19.811  1   76.99  ? 101 LEU C O   1 
ATOM   7432 C  CB  . LEU D 2 105 ? -53.361 31.151  20.208  1   87.45  ? 101 LEU C CB  1 
ATOM   7433 C  CG  . LEU D 2 105 ? -54.66  30.329  20.21   1   90.67  ? 101 LEU C CG  1 
ATOM   7434 C  CD1 . LEU D 2 105 ? -54.98  29.826  18.806  1   95.77  ? 101 LEU C CD1 1 
ATOM   7435 C  CD2 . LEU D 2 105 ? -54.691 29.185  21.218  1   85.63  ? 101 LEU C CD2 1 
ATOM   7436 N  N   . PRO D 2 106 ? -51.138 29.665  18.262  1   77.93  ? 102 PRO C N   1 
ATOM   7437 C  CA  . PRO D 2 106 ? -50.595 28.628  17.376  1   74.38  ? 102 PRO C CA  1 
ATOM   7438 C  C   . PRO D 2 106 ? -49.605 27.65   17.996  1   70.58  ? 102 PRO C C   1 
ATOM   7439 O  O   . PRO D 2 106 ? -49.611 26.465  17.665  1   69.13  ? 102 PRO C O   1 
ATOM   7440 C  CB  . PRO D 2 106 ? -49.905 29.437  16.266  1   76.63  ? 102 PRO C CB  1 
ATOM   7441 C  CG  . PRO D 2 106 ? -50.678 30.733  16.199  1   79.59  ? 102 PRO C CG  1 
ATOM   7442 C  CD  . PRO D 2 106 ? -51.144 30.994  17.621  1   78.73  ? 102 PRO C CD  1 
ATOM   7443 N  N   . LEU D 2 107 ? -48.711 28.181  18.844  1   69.02  ? 103 LEU C N   1 
ATOM   7444 C  CA  . LEU D 2 107 ? -47.641 27.402  19.452  1   64.38  ? 103 LEU C CA  1 
ATOM   7445 C  C   . LEU D 2 107 ? -48.2   26.558  20.6    1   62.33  ? 103 LEU C C   1 
ATOM   7446 O  O   . LEU D 2 107 ? -47.846 25.388  20.757  1   58.78  ? 103 LEU C O   1 
ATOM   7447 C  CB  . LEU D 2 107 ? -46.51  28.328  19.895  1   63.58  ? 103 LEU C CB  1 
ATOM   7448 C  CG  . LEU D 2 107 ? -45.286 27.64   20.512  1   64.57  ? 103 LEU C CG  1 
ATOM   7449 C  CD1 . LEU D 2 107 ? -44.728 26.547  19.638  1   63.07  ? 103 LEU C CD1 1 
ATOM   7450 C  CD2 . LEU D 2 107 ? -44.189 28.644  20.788  1   69.04  ? 103 LEU C CD2 1 
ATOM   7451 N  N   . ILE D 2 108 ? -49.1   27.165  21.388  1   61.98  ? 104 ILE C N   1 
ATOM   7452 C  CA  . ILE D 2 108 ? -49.88  26.419  22.362  1   60.76  ? 104 ILE C CA  1 
ATOM   7453 C  C   . ILE D 2 108 ? -50.541 25.222  21.674  1   62.69  ? 104 ILE C C   1 
ATOM   7454 O  O   . ILE D 2 108 ? -50.43  24.078  22.125  1   60.41  ? 104 ILE C O   1 
ATOM   7455 C  CB  . ILE D 2 108 ? -50.896 27.315  23.1    1   58.92  ? 104 ILE C CB  1 
ATOM   7456 C  CG1 . ILE D 2 108 ? -50.198 28.561  23.674  1   59.38  ? 104 ILE C CG1 1 
ATOM   7457 C  CG2 . ILE D 2 108 ? -51.616 26.503  24.184  1   54.98  ? 104 ILE C CG2 1 
ATOM   7458 C  CD1 . ILE D 2 108 ? -50.978 29.339  24.726  1   60.43  ? 104 ILE C CD1 1 
ATOM   7459 N  N   . LYS D 2 109 ? -51.217 25.503  20.557  1   64.68  ? 105 LYS C N   1 
ATOM   7460 C  CA  . LYS D 2 109 ? -51.977 24.475  19.874  1   65.82  ? 105 LYS C CA  1 
ATOM   7461 C  C   . LYS D 2 109 ? -51.033 23.347  19.46   1   64.62  ? 105 LYS C C   1 
ATOM   7462 O  O   . LYS D 2 109 ? -51.341 22.175  19.667  1   64.27  ? 105 LYS C O   1 
ATOM   7463 C  CB  . LYS D 2 109 ? -52.694 25.114  18.682  1   66.49  ? 105 LYS C CB  1 
ATOM   7464 C  CG  . LYS D 2 109 ? -53.494 24.16   17.793  1   66.68  ? 105 LYS C CG  1 
ATOM   7465 C  CD  . LYS D 2 109 ? -54.23  24.971  16.733  1   71.46  ? 105 LYS C CD  1 
ATOM   7466 C  CE  . LYS D 2 109 ? -55.293 25.926  17.285  1   69.99  ? 105 LYS C CE  1 
ATOM   7467 N  NZ  . LYS D 2 109 ? -55.232 27.207  16.573  1   69.82  ? 105 LYS C NZ  1 
ATOM   7468 N  N   . SER D 2 110 ? -49.886 23.726  18.881  1   64.19  ? 106 SER C N   1 
ATOM   7469 C  CA  . SER D 2 110 ? -48.879 22.784  18.416  1   62.37  ? 106 SER C CA  1 
ATOM   7470 C  C   . SER D 2 110 ? -48.317 21.967  19.581  1   61.96  ? 106 SER C C   1 
ATOM   7471 O  O   . SER D 2 110 ? -48.147 20.754  19.449  1   63.41  ? 106 SER C O   1 
ATOM   7472 C  CB  . SER D 2 110 ? -47.785 23.501  17.684  1   62.37  ? 106 SER C CB  1 
ATOM   7473 O  OG  . SER D 2 110 ? -46.726 22.608  17.388  1   63.96  ? 106 SER C OG  1 
ATOM   7474 N  N   . TYR D 2 111 ? -48.032 22.626  20.718  1   58.17  ? 107 TYR C N   1 
ATOM   7475 C  CA  . TYR D 2 111 ? -47.431 21.929  21.843  1   56.33  ? 107 TYR C CA  1 
ATOM   7476 C  C   . TYR D 2 111 ? -48.418 20.905  22.41   1   56.69  ? 107 TYR C C   1 
ATOM   7477 O  O   . TYR D 2 111 ? -48.053 19.79   22.762  1   56.54  ? 107 TYR C O   1 
ATOM   7478 C  CB  . TYR D 2 111 ? -46.906 22.893  22.906  1   55.08  ? 107 TYR C CB  1 
ATOM   7479 C  CG  . TYR D 2 111 ? -45.57  23.557  22.626  1   54.73  ? 107 TYR C CG  1 
ATOM   7480 C  CD1 . TYR D 2 111 ? -44.738 23.144  21.581  1   54.74  ? 107 TYR C CD1 1 
ATOM   7481 C  CD2 . TYR D 2 111 ? -45.12  24.58   23.454  1   54.53  ? 107 TYR C CD2 1 
ATOM   7482 C  CE1 . TYR D 2 111 ? -43.496 23.733  21.37   1   55.43  ? 107 TYR C CE1 1 
ATOM   7483 C  CE2 . TYR D 2 111 ? -43.886 25.178  23.251  1   55.96  ? 107 TYR C CE2 1 
ATOM   7484 C  CZ  . TYR D 2 111 ? -43.079 24.759  22.203  1   57.42  ? 107 TYR C CZ  1 
ATOM   7485 O  OH  . TYR D 2 111 ? -41.877 25.369  22.016  1   61.55  ? 107 TYR C OH  1 
ATOM   7486 N  N   . LEU D 2 112 ? -49.691 21.275  22.471  1   59.09  ? 108 LEU C N   1 
ATOM   7487 C  CA  . LEU D 2 112 ? -50.69  20.396  23.049  1   58.71  ? 108 LEU C CA  1 
ATOM   7488 C  C   . LEU D 2 112 ? -50.921 19.227  22.093  1   60.2   ? 108 LEU C C   1 
ATOM   7489 O  O   . LEU D 2 112 ? -51.111 18.096  22.534  1   58.83  ? 108 LEU C O   1 
ATOM   7490 C  CB  . LEU D 2 112 ? -51.962 21.205  23.31   1   59.79  ? 108 LEU C CB  1 
ATOM   7491 C  CG  . LEU D 2 112 ? -53.169 20.406  23.804  1   61.58  ? 108 LEU C CG  1 
ATOM   7492 C  CD1 . LEU D 2 112 ? -52.86  19.677  25.087  1   60.98  ? 108 LEU C CD1 1 
ATOM   7493 C  CD2 . LEU D 2 112 ? -54.369 21.292  23.996  1   62.54  ? 108 LEU C CD2 1 
ATOM   7494 N  N   . PHE D 2 113 ? -50.889 19.51   20.783  1   61.46  ? 109 PHE C N   1 
ATOM   7495 C  CA  . PHE D 2 113 ? -51.111 18.482  19.782  1   67.91  ? 109 PHE C CA  1 
ATOM   7496 C  C   . PHE D 2 113 ? -50.017 17.424  19.921  1   68.62  ? 109 PHE C C   1 
ATOM   7497 O  O   . PHE D 2 113 ? -50.286 16.221  19.99   1   68.6   ? 109 PHE C O   1 
ATOM   7498 C  CB  . PHE D 2 113 ? -51.15  19.104  18.381  1   71.94  ? 109 PHE C CB  1 
ATOM   7499 C  CG  . PHE D 2 113 ? -51.66  18.203  17.264  1   75.07  ? 109 PHE C CG  1 
ATOM   7500 C  CD1 . PHE D 2 113 ? -52.964 17.707  17.29   1   79.45  ? 109 PHE C CD1 1 
ATOM   7501 C  CD2 . PHE D 2 113 ? -50.849 17.87   16.18   1   78.52  ? 109 PHE C CD2 1 
ATOM   7502 C  CE1 . PHE D 2 113 ? -53.443 16.886  16.273  1   83.63  ? 109 PHE C CE1 1 
ATOM   7503 C  CE2 . PHE D 2 113 ? -51.327 17.038  15.166  1   81.77  ? 109 PHE C CE2 1 
ATOM   7504 C  CZ  . PHE D 2 113 ? -52.618 16.544  15.213  1   82.4   ? 109 PHE C CZ  1 
ATOM   7505 N  N   . GLN D 2 114 ? -48.774 17.903  20.007  1   66.72  ? 110 GLN C N   1 
ATOM   7506 C  CA  . GLN D 2 114 ? -47.625 17.017  20.084  1   64.09  ? 110 GLN C CA  1 
ATOM   7507 C  C   . GLN D 2 114 ? -47.674 16.211  21.376  1   58.99  ? 110 GLN C C   1 
ATOM   7508 O  O   . GLN D 2 114 ? -47.4   15.012  21.373  1   55.97  ? 110 GLN C O   1 
ATOM   7509 C  CB  . GLN D 2 114 ? -46.341 17.829  19.928  1   63.5   ? 110 GLN C CB  1 
ATOM   7510 C  CG  . GLN D 2 114 ? -46.055 18.285  18.5    1   62.04  ? 110 GLN C CG  1 
ATOM   7511 C  CD  . GLN D 2 114 ? -44.785 19.094  18.453  1   65.94  ? 110 GLN C CD  1 
ATOM   7512 O  OE1 . GLN D 2 114 ? -43.681 18.539  18.575  1   68.92  ? 110 GLN C OE1 1 
ATOM   7513 N  NE2 . GLN D 2 114 ? -44.942 20.414  18.395  1   61.31  ? 110 GLN C NE2 1 
ATOM   7514 N  N   . LEU D 2 115 ? -48.018 16.89   22.48   1   60.01  ? 111 LEU C N   1 
ATOM   7515 C  CA  . LEU D 2 115 ? -48.011 16.264  23.796  1   55.93  ? 111 LEU C CA  1 
ATOM   7516 C  C   . LEU D 2 115 ? -48.961 15.076  23.761  1   56.31  ? 111 LEU C C   1 
ATOM   7517 O  O   . LEU D 2 115 ? -48.665 14.041  24.35   1   53.75  ? 111 LEU C O   1 
ATOM   7518 C  CB  . LEU D 2 115 ? -48.374 17.253  24.898  1   52.36  ? 111 LEU C CB  1 
ATOM   7519 C  CG  . LEU D 2 115 ? -47.312 18.29   25.268  1   51.39  ? 111 LEU C CG  1 
ATOM   7520 C  CD1 . LEU D 2 115 ? -47.823 19.258  26.324  1   48.85  ? 111 LEU C CD1 1 
ATOM   7521 C  CD2 . LEU D 2 115 ? -46.048 17.602  25.745  1   51.01  ? 111 LEU C CD2 1 
ATOM   7522 N  N   . LEU D 2 116 ? -50.072 15.242  23.024  1   55.8   ? 112 LEU C N   1 
ATOM   7523 C  CA  . LEU D 2 116 ? -51.115 14.239  22.966  1   58.91  ? 112 LEU C CA  1 
ATOM   7524 C  C   . LEU D 2 116 ? -50.688 13.068  22.087  1   61.84  ? 112 LEU C C   1 
ATOM   7525 O  O   . LEU D 2 116 ? -51.035 11.914  22.372  1   62.13  ? 112 LEU C O   1 
ATOM   7526 C  CB  . LEU D 2 116 ? -52.367 14.911  22.423  1   62.51  ? 112 LEU C CB  1 
ATOM   7527 C  CG  . LEU D 2 116 ? -53.08  15.841  23.403  1   63.59  ? 112 LEU C CG  1 
ATOM   7528 C  CD1 . LEU D 2 116 ? -54.118 16.67   22.68   1   63.48  ? 112 LEU C CD1 1 
ATOM   7529 C  CD2 . LEU D 2 116 ? -53.712 14.987  24.485  1   65.74  ? 112 LEU C CD2 1 
ATOM   7530 N  N   . GLN D 2 117 ? -49.975 13.385  20.996  1   63.24  ? 113 GLN C N   1 
ATOM   7531 C  CA  . GLN D 2 117 ? -49.497 12.365  20.074  1   61.4   ? 113 GLN C CA  1 
ATOM   7532 C  C   . GLN D 2 117 ? -48.473 11.496  20.801  1   63.05  ? 113 GLN C C   1 
ATOM   7533 O  O   . GLN D 2 117 ? -48.523 10.267  20.734  1   63.01  ? 113 GLN C O   1 
ATOM   7534 C  CB  . GLN D 2 117 ? -48.858 13.043  18.868  1   61.27  ? 113 GLN C CB  1 
ATOM   7535 C  CG  . GLN D 2 117 ? -49.864 13.513  17.835  1   67.24  ? 113 GLN C CG  1 
ATOM   7536 C  CD  . GLN D 2 117 ? -49.187 13.9    16.544  1   76.01  ? 113 GLN C CD  1 
ATOM   7537 O  OE1 . GLN D 2 117 ? -49.343 13.239  15.512  1   87.2   ? 113 GLN C OE1 1 
ATOM   7538 N  NE2 . GLN D 2 117 ? -48.421 14.979  16.585  1   76.8   ? 113 GLN C NE2 1 
ATOM   7539 N  N   . GLY D 2 118 ? -47.544 12.172  21.499  1   62.1   ? 114 GLY C N   1 
ATOM   7540 C  CA  . GLY D 2 118 ? -46.615 11.519  22.396  1   56.04  ? 114 GLY C CA  1 
ATOM   7541 C  C   . GLY D 2 118 ? -47.34  10.605  23.383  1   54.91  ? 114 GLY C C   1 
ATOM   7542 O  O   . GLY D 2 118 ? -46.985 9.434   23.528  1   57.28  ? 114 GLY C O   1 
ATOM   7543 N  N   . LEU D 2 119 ? -48.342 11.156  24.074  1   53.37  ? 115 LEU C N   1 
ATOM   7544 C  CA  . LEU D 2 119 ? -48.955 10.468  25.196  1   54.36  ? 115 LEU C CA  1 
ATOM   7545 C  C   . LEU D 2 119 ? -49.798 9.285   24.71   1   56.69  ? 115 LEU C C   1 
ATOM   7546 O  O   . LEU D 2 119 ? -49.849 8.243   25.375  1   55.45  ? 115 LEU C O   1 
ATOM   7547 C  CB  . LEU D 2 119 ? -49.77  11.47   26.006  1   53.46  ? 115 LEU C CB  1 
ATOM   7548 C  CG  . LEU D 2 119 ? -50.539 10.866  27.179  1   55.01  ? 115 LEU C CG  1 
ATOM   7549 C  CD1 . LEU D 2 119 ? -49.581 10.392  28.235  1   55.05  ? 115 LEU C CD1 1 
ATOM   7550 C  CD2 . LEU D 2 119 ? -51.507 11.863  27.758  1   59.44  ? 115 LEU C CD2 1 
ATOM   7551 N  N   . ALA D 2 120 ? -50.451 9.463   23.549  1   55.67  ? 116 ALA C N   1 
ATOM   7552 C  CA  . ALA D 2 120 ? -51.288 8.439   22.957  1   57.34  ? 116 ALA C CA  1 
ATOM   7553 C  C   . ALA D 2 120 ? -50.438 7.206   22.665  1   58.87  ? 116 ALA C C   1 
ATOM   7554 O  O   . ALA D 2 120 ? -50.884 6.084   22.881  1   60.01  ? 116 ALA C O   1 
ATOM   7555 C  CB  . ALA D 2 120 ? -51.956 8.983   21.708  1   58.64  ? 116 ALA C CB  1 
ATOM   7556 N  N   . PHE D 2 121 ? -49.217 7.436   22.161  1   58.8   ? 117 PHE C N   1 
ATOM   7557 C  CA  . PHE D 2 121 ? -48.201 6.408   21.97   1   58.72  ? 117 PHE C CA  1 
ATOM   7558 C  C   . PHE D 2 121 ? -47.918 5.674   23.283  1   58     ? 117 PHE C C   1 
ATOM   7559 O  O   . PHE D 2 121 ? -47.861 4.445   23.296  1   61.24  ? 117 PHE C O   1 
ATOM   7560 C  CB  . PHE D 2 121 ? -46.902 7.014   21.428  1   58.58  ? 117 PHE C CB  1 
ATOM   7561 C  CG  . PHE D 2 121 ? -46.013 6.009   20.711  1   59.22  ? 117 PHE C CG  1 
ATOM   7562 C  CD1 . PHE D 2 121 ? -45.125 5.196   21.419  1   53.32  ? 117 PHE C CD1 1 
ATOM   7563 C  CD2 . PHE D 2 121 ? -46.08  5.877   19.32   1   59.7   ? 117 PHE C CD2 1 
ATOM   7564 C  CE1 . PHE D 2 121 ? -44.349 4.264   20.735  1   53.47  ? 117 PHE C CE1 1 
ATOM   7565 C  CE2 . PHE D 2 121 ? -45.286 4.954   18.647  1   58.76  ? 117 PHE C CE2 1 
ATOM   7566 C  CZ  . PHE D 2 121 ? -44.428 4.141   19.357  1   55.26  ? 117 PHE C CZ  1 
ATOM   7567 N  N   . CYS D 2 122 ? -47.743 6.412   24.39   1   54.33  ? 118 CYS C N   1 
ATOM   7568 C  CA  . CYS D 2 122 ? -47.546 5.744   25.668  1   53.25  ? 118 CYS C CA  1 
ATOM   7569 C  C   . CYS D 2 122 ? -48.68  4.764   25.928  1   56.83  ? 118 CYS C C   1 
ATOM   7570 O  O   . CYS D 2 122 ? -48.44  3.561   26.027  1   59.13  ? 118 CYS C O   1 
ATOM   7571 C  CB  . CYS D 2 122 ? -47.401 6.725   26.811  1   50.65  ? 118 CYS C CB  1 
ATOM   7572 S  SG  . CYS D 2 122 ? -45.824 7.586   26.648  1   57.24  ? 118 CYS C SG  1 
ATOM   7573 N  N   . HIS D 2 123 ? -49.908 5.299   25.933  1   57.8   ? 119 HIS C N   1 
ATOM   7574 C  CA  . HIS D 2 123 ? -51.103 4.544   26.268  1   57.23  ? 119 HIS C CA  1 
ATOM   7575 C  C   . HIS D 2 123 ? -51.258 3.332   25.332  1   56.8   ? 119 HIS C C   1 
ATOM   7576 O  O   . HIS D 2 123 ? -51.657 2.255   25.78   1   58.19  ? 119 HIS C O   1 
ATOM   7577 C  CB  . HIS D 2 123 ? -52.292 5.5     26.446  1   58.48  ? 119 HIS C CB  1 
ATOM   7578 C  CG  . HIS D 2 123 ? -52.131 6.512   27.548  1   58.18  ? 119 HIS C CG  1 
ATOM   7579 N  ND1 . HIS D 2 123 ? -52.832 7.699   27.592  1   59.45  ? 119 HIS C ND1 1 
ATOM   7580 C  CD2 . HIS D 2 123 ? -51.357 6.515   28.656  1   57.25  ? 119 HIS C CD2 1 
ATOM   7581 C  CE1 . HIS D 2 123 ? -52.463 8.389   28.672  1   58.18  ? 119 HIS C CE1 1 
ATOM   7582 N  NE2 . HIS D 2 123 ? -51.574 7.687   29.337  1   55.98  ? 119 HIS C NE2 1 
ATOM   7583 N  N   . SER D 2 124 ? -50.896 3.485   24.05   1   53.53  ? 120 SER C N   1 
ATOM   7584 C  CA  . SER D 2 124 ? -51.061 2.423   23.068  1   55.19  ? 120 SER C CA  1 
ATOM   7585 C  C   . SER D 2 124 ? -50.064 1.309   23.337  1   55.89  ? 120 SER C C   1 
ATOM   7586 O  O   . SER D 2 124 ? -50.139 0.253   22.702  1   55.23  ? 120 SER C O   1 
ATOM   7587 C  CB  . SER D 2 124 ? -50.83  2.907   21.663  1   57.47  ? 120 SER C CB  1 
ATOM   7588 O  OG  . SER D 2 124 ? -51.549 4.095   21.378  1   62.5   ? 120 SER C OG  1 
ATOM   7589 N  N   . HIS D 2 125 ? -49.093 1.599   24.214  1   55.9   ? 121 HIS C N   1 
ATOM   7590 C  CA  . HIS D 2 125 ? -47.968 0.715   24.489  1   57.01  ? 121 HIS C CA  1 
ATOM   7591 C  C   . HIS D 2 125 ? -47.977 0.387   25.973  1   56.25  ? 121 HIS C C   1 
ATOM   7592 O  O   . HIS D 2 125 ? -46.93  0.116   26.538  1   55.02  ? 121 HIS C O   1 
ATOM   7593 C  CB  . HIS D 2 125 ? -46.673 1.342   23.949  1   56.66  ? 121 HIS C CB  1 
ATOM   7594 C  CG  . HIS D 2 125 ? -46.718 1.522   22.457  1   62.71  ? 121 HIS C CG  1 
ATOM   7595 N  ND1 . HIS D 2 125 ? -47.373 2.576   21.835  1   65.56  ? 121 HIS C ND1 1 
ATOM   7596 C  CD2 . HIS D 2 125 ? -46.243 0.745   21.459  1   63.34  ? 121 HIS C CD2 1 
ATOM   7597 C  CE1 . HIS D 2 125 ? -47.264 2.463   20.516  1   64.5   ? 121 HIS C CE1 1 
ATOM   7598 N  NE2 . HIS D 2 125 ? -46.585 1.352   20.271  1   68.63  ? 121 HIS C NE2 1 
ATOM   7599 N  N   . ARG D 2 126 ? -49.165 0.372   26.573  1   58.75  ? 122 ARG C N   1 
ATOM   7600 C  CA  . ARG D 2 126 ? -49.354 0.005   28.004  1   59.47  ? 122 ARG C CA  1 
ATOM   7601 C  C   . ARG D 2 126 ? -48.364 0.717   28.953  1   57     ? 122 ARG C C   1 
ATOM   7602 O  O   . ARG D 2 126 ? -47.893 0.06    29.885  1   58.1   ? 122 ARG C O   1 
ATOM   7603 C  CB  . ARG D 2 126 ? -49.375 -1.521  28.187  1   57.9   ? 122 ARG C CB  1 
ATOM   7604 C  CG  . ARG D 2 126 ? -48.38  -2.456  27.514  1   56.61  ? 122 ARG C CG  1 
ATOM   7605 C  CD  . ARG D 2 126 ? -47.129 -2.625  28.352  1   55.86  ? 122 ARG C CD  1 
ATOM   7606 N  NE  . ARG D 2 126 ? -46.14  -3.484  27.696  1   60.95  ? 122 ARG C NE  1 
ATOM   7607 C  CZ  . ARG D 2 126 ? -45.011 -3.068  27.147  1   61.69  ? 122 ARG C CZ  1 
ATOM   7608 N  NH1 . ARG D 2 126 ? -44.776 -1.778  27.011  1   53.41  ? 122 ARG C NH1 1 
ATOM   7609 N  NH2 . ARG D 2 126 ? -44.121 -3.947  26.73   1   61.99  ? 122 ARG C NH2 1 
ATOM   7610 N  N   . VAL D 2 127 ? -48.152 2.023   28.794  1   54.44  ? 123 VAL C N   1 
ATOM   7611 C  CA  . VAL D 2 127 ? -47.278 2.753   29.715  1   51.85  ? 123 VAL C CA  1 
ATOM   7612 C  C   . VAL D 2 127 ? -48.032 3.966   30.256  1   49.59  ? 123 VAL C C   1 
ATOM   7613 O  O   . VAL D 2 127 ? -48.558 4.772   29.496  1   50.89  ? 123 VAL C O   1 
ATOM   7614 C  CB  . VAL D 2 127 ? -45.981 3.241   29.023  1   50.58  ? 123 VAL C CB  1 
ATOM   7615 C  CG1 . VAL D 2 127 ? -45.251 4.291   29.859  1   44.94  ? 123 VAL C CG1 1 
ATOM   7616 C  CG2 . VAL D 2 127 ? -45.059 2.1     28.587  1   48.07  ? 123 VAL C CG2 1 
ATOM   7617 N  N   . LEU D 2 128 ? -48.062 4.107   31.571  1   49.44  ? 124 LEU C N   1 
ATOM   7618 C  CA  . LEU D 2 128 ? -48.543 5.334   32.191  1   51.66  ? 124 LEU C CA  1 
ATOM   7619 C  C   . LEU D 2 128 ? -47.329 6.205   32.511  1   52     ? 124 LEU C C   1 
ATOM   7620 O  O   . LEU D 2 128 ? -46.333 5.683   33.026  1   53.57  ? 124 LEU C O   1 
ATOM   7621 C  CB  . LEU D 2 128 ? -49.309 5.013   33.479  1   50.86  ? 124 LEU C CB  1 
ATOM   7622 C  CG  . LEU D 2 128 ? -50.595 4.193   33.358  1   52.52  ? 124 LEU C CG  1 
ATOM   7623 C  CD1 . LEU D 2 128 ? -51.146 3.852   34.733  1   51.75  ? 124 LEU C CD1 1 
ATOM   7624 C  CD2 . LEU D 2 128 ? -51.615 4.949   32.536  1   53.5   ? 124 LEU C CD2 1 
ATOM   7625 N  N   . HIS D 2 129 ? -47.428 7.524   32.269  1   48.8   ? 125 HIS C N   1 
ATOM   7626 C  CA  . HIS D 2 129 ? -46.318 8.408   32.57   1   48.28  ? 125 HIS C CA  1 
ATOM   7627 C  C   . HIS D 2 129 ? -46.309 8.776   34.056  1   50.12  ? 125 HIS C C   1 
ATOM   7628 O  O   . HIS D 2 129 ? -45.283 8.618   34.716  1   49.41  ? 125 HIS C O   1 
ATOM   7629 C  CB  . HIS D 2 129 ? -46.334 9.647   31.68   1   49.22  ? 125 HIS C CB  1 
ATOM   7630 C  CG  . HIS D 2 129 ? -45.132 10.502  31.882  1   52     ? 125 HIS C CG  1 
ATOM   7631 N  ND1 . HIS D 2 129 ? -44.907 11.2    33.05   1   52.75  ? 125 HIS C ND1 1 
ATOM   7632 C  CD2 . HIS D 2 129 ? -44.086 10.763  31.085  1   52.16  ? 125 HIS C CD2 1 
ATOM   7633 C  CE1 . HIS D 2 129 ? -43.762 11.861  32.952  1   53.22  ? 125 HIS C CE1 1 
ATOM   7634 N  NE2 . HIS D 2 129 ? -43.249 11.618  31.764  1   54.72  ? 125 HIS C NE2 1 
ATOM   7635 N  N   . ARG D 2 130 ? -47.428 9.331   34.546  1   49.31  ? 126 ARG C N   1 
ATOM   7636 C  CA  . ARG D 2 130 ? -47.693 9.531   35.966  1   50.07  ? 126 ARG C CA  1 
ATOM   7637 C  C   . ARG D 2 130 ? -46.868 10.671  36.569  1   49.78  ? 126 ARG C C   1 
ATOM   7638 O  O   . ARG D 2 130 ? -46.821 10.844  37.789  1   53.83  ? 126 ARG C O   1 
ATOM   7639 C  CB  . ARG D 2 130 ? -47.504 8.242   36.78   1   47.98  ? 126 ARG C CB  1 
ATOM   7640 C  CG  . ARG D 2 130 ? -48.366 7.083   36.317  1   46.11  ? 126 ARG C CG  1 
ATOM   7641 C  CD  . ARG D 2 130 ? -48.444 5.992   37.361  1   46.99  ? 126 ARG C CD  1 
ATOM   7642 N  NE  . ARG D 2 130 ? -47.126 5.459   37.733  1   45.97  ? 126 ARG C NE  1 
ATOM   7643 C  CZ  . ARG D 2 130 ? -46.902 4.545   38.676  1   45.62  ? 126 ARG C CZ  1 
ATOM   7644 N  NH1 . ARG D 2 130 ? -47.904 3.927   39.276  1   45.17  ? 126 ARG C NH1 1 
ATOM   7645 N  NH2 . ARG D 2 130 ? -45.657 4.242   38.994  1   44.52  ? 126 ARG C NH2 1 
ATOM   7646 N  N   . ASP D 2 131 ? -46.251 11.496  35.735  1   48.17  ? 127 ASP C N   1 
ATOM   7647 C  CA  . ASP D 2 131 ? -45.562 12.645  36.289  1   50.72  ? 127 ASP C CA  1 
ATOM   7648 C  C   . ASP D 2 131 ? -45.494 13.743  35.234  1   51.38  ? 127 ASP C C   1 
ATOM   7649 O  O   . ASP D 2 131 ? -44.458 14.374  35.057  1   50.73  ? 127 ASP C O   1 
ATOM   7650 C  CB  . ASP D 2 131 ? -44.185 12.271  36.805  1   49.88  ? 127 ASP C CB  1 
ATOM   7651 C  CG  . ASP D 2 131 ? -43.554 13.297  37.728  1   52.23  ? 127 ASP C CG  1 
ATOM   7652 O  OD1 . ASP D 2 131 ? -44.313 14.11   38.327  1   55.01  ? 127 ASP C OD1 1 
ATOM   7653 O  OD2 . ASP D 2 131 ? -42.312 13.306  37.79   1   52.63  ? 127 ASP C OD2 1 
ATOM   7654 N  N   . LEU D 2 132 ? -46.615 13.985  34.555  1   51.39  ? 128 LEU C N   1 
ATOM   7655 C  CA  . LEU D 2 132 ? -46.622 15.007  33.526  1   52.68  ? 128 LEU C CA  1 
ATOM   7656 C  C   . LEU D 2 132 ? -46.768 16.36   34.207  1   52.56  ? 128 LEU C C   1 
ATOM   7657 O  O   . LEU D 2 132 ? -47.772 16.637  34.841  1   60.51  ? 128 LEU C O   1 
ATOM   7658 C  CB  . LEU D 2 132 ? -47.707 14.725  32.488  1   50.35  ? 128 LEU C CB  1 
ATOM   7659 C  CG  . LEU D 2 132 ? -47.481 13.464  31.642  1   49.65  ? 128 LEU C CG  1 
ATOM   7660 C  CD1 . LEU D 2 132 ? -48.78  12.945  31.053  1   50.1   ? 128 LEU C CD1 1 
ATOM   7661 C  CD2 . LEU D 2 132 ? -46.474 13.707  30.543  1   48.52  ? 128 LEU C CD2 1 
ATOM   7662 N  N   . LYS D 2 133 ? -45.725 17.17   34.111  1   48.62  ? 129 LYS C N   1 
ATOM   7663 C  CA  . LYS D 2 133 ? -45.785 18.55   34.533  1   49.6   ? 129 LYS C CA  1 
ATOM   7664 C  C   . LYS D 2 133 ? -44.791 19.338  33.691  1   52.11  ? 129 LYS C C   1 
ATOM   7665 O  O   . LYS D 2 133 ? -43.932 18.786  33.004  1   52.51  ? 129 LYS C O   1 
ATOM   7666 C  CB  . LYS D 2 133 ? -45.414 18.609  36.009  1   50.16  ? 129 LYS C CB  1 
ATOM   7667 C  CG  . LYS D 2 133 ? -44.107 17.898  36.3    1   50.25  ? 129 LYS C CG  1 
ATOM   7668 C  CD  . LYS D 2 133 ? -43.649 18.122  37.737  1   49.61  ? 129 LYS C CD  1 
ATOM   7669 C  CE  . LYS D 2 133 ? -42.504 17.243  38.057  1   49     ? 129 LYS C CE  1 
ATOM   7670 N  NZ  . LYS D 2 133 ? -42.019 17.63   39.377  1   52.05  ? 129 LYS C NZ  1 
ATOM   7671 N  N   . PRO D 2 134 ? -44.88  20.675  33.663  1   53.11  ? 130 PRO C N   1 
ATOM   7672 C  CA  . PRO D 2 134 ? -44.15  21.395  32.623  1   51.74  ? 130 PRO C CA  1 
ATOM   7673 C  C   . PRO D 2 134 ? -42.641 21.148  32.723  1   52.81  ? 130 PRO C C   1 
ATOM   7674 O  O   . PRO D 2 134 ? -41.927 21.254  31.726  1   54.7   ? 130 PRO C O   1 
ATOM   7675 C  CB  . PRO D 2 134 ? -44.572 22.847  32.818  1   53.35  ? 130 PRO C CB  1 
ATOM   7676 C  CG  . PRO D 2 134 ? -45.733 22.812  33.827  1   53.82  ? 130 PRO C CG  1 
ATOM   7677 C  CD  . PRO D 2 134 ? -45.647 21.518  34.595  1   51.18  ? 130 PRO C CD  1 
ATOM   7678 N  N   . GLN D 2 135 ? -42.159 20.791  33.923  1   51.09  ? 131 GLN C N   1 
ATOM   7679 C  CA  . GLN D 2 135 ? -40.732 20.592  34.147  1   49.72  ? 131 GLN C CA  1 
ATOM   7680 C  C   . GLN D 2 135 ? -40.245 19.323  33.447  1   50.2   ? 131 GLN C C   1 
ATOM   7681 O  O   . GLN D 2 135 ? -39.052 19.206  33.198  1   48.27  ? 131 GLN C O   1 
ATOM   7682 C  CB  . GLN D 2 135 ? -40.347 20.43   35.612  1   47.16  ? 131 GLN C CB  1 
ATOM   7683 C  CG  . GLN D 2 135 ? -40.675 21.645  36.472  1   53.62  ? 131 GLN C CG  1 
ATOM   7684 C  CD  . GLN D 2 135 ? -42.135 21.846  36.848  1   57.04  ? 131 GLN C CD  1 
ATOM   7685 O  OE1 . GLN D 2 135 ? -43.059 21.154  36.383  1   58.23  ? 131 GLN C OE1 1 
ATOM   7686 N  NE2 . GLN D 2 135 ? -42.35  22.868  37.671  1   54.06  ? 131 GLN C NE2 1 
ATOM   7687 N  N   . ASN D 2 136 ? -41.173 18.407  33.121  1   47.55  ? 132 ASN C N   1 
ATOM   7688 C  CA  . ASN D 2 136 ? -40.834 17.106  32.573  1   44.89  ? 132 ASN C CA  1 
ATOM   7689 C  C   . ASN D 2 136 ? -41.135 17.075  31.076  1   44.29  ? 132 ASN C C   1 
ATOM   7690 O  O   . ASN D 2 136 ? -41.127 16.005  30.473  1   44.13  ? 132 ASN C O   1 
ATOM   7691 C  CB  . ASN D 2 136 ? -41.498 15.968  33.348  1   43.95  ? 132 ASN C CB  1 
ATOM   7692 C  CG  . ASN D 2 136 ? -40.911 15.752  34.73   1   46.63  ? 132 ASN C CG  1 
ATOM   7693 O  OD1 . ASN D 2 136 ? -39.894 16.369  35.093  1   50.27  ? 132 ASN C OD1 1 
ATOM   7694 N  ND2 . ASN D 2 136 ? -41.549 14.907  35.532  1   44.2   ? 132 ASN C ND2 1 
ATOM   7695 N  N   . LEU D 2 137 ? -41.416 18.243  30.483  1   43.65  ? 133 LEU C N   1 
ATOM   7696 C  CA  . LEU D 2 137 ? -41.685 18.346  29.053  1   43.56  ? 133 LEU C CA  1 
ATOM   7697 C  C   . LEU D 2 137 ? -40.601 19.229  28.43   1   47.11  ? 133 LEU C C   1 
ATOM   7698 O  O   . LEU D 2 137 ? -40.39  20.366  28.886  1   46.98  ? 133 LEU C O   1 
ATOM   7699 C  CB  . LEU D 2 137 ? -43.072 18.945  28.839  1   44.16  ? 133 LEU C CB  1 
ATOM   7700 C  CG  . LEU D 2 137 ? -44.24  18.241  29.547  1   45.55  ? 133 LEU C CG  1 
ATOM   7701 C  CD1 . LEU D 2 137 ? -45.556 18.987  29.389  1   44.16  ? 133 LEU C CD1 1 
ATOM   7702 C  CD2 . LEU D 2 137 ? -44.384 16.801  29.073  1   44.21  ? 133 LEU C CD2 1 
ATOM   7703 N  N   . LEU D 2 138 ? -39.901 18.687  27.412  1   45.24  ? 134 LEU C N   1 
ATOM   7704 C  CA  . LEU D 2 138 ? -38.732 19.349  26.85   1   45.6   ? 134 LEU C CA  1 
ATOM   7705 C  C   . LEU D 2 138 ? -39.038 19.889  25.461  1   47.9   ? 134 LEU C C   1 
ATOM   7706 O  O   . LEU D 2 138 ? -39.726 19.219  24.691  1   52.09  ? 134 LEU C O   1 
ATOM   7707 C  CB  . LEU D 2 138 ? -37.601 18.325  26.84   1   45.03  ? 134 LEU C CB  1 
ATOM   7708 C  CG  . LEU D 2 138 ? -37.27  17.721  28.215  1   43.49  ? 134 LEU C CG  1 
ATOM   7709 C  CD1 . LEU D 2 138 ? -36.182 16.687  28.055  1   43.57  ? 134 LEU C CD1 1 
ATOM   7710 C  CD2 . LEU D 2 138 ? -36.896 18.719  29.303  1   38.1   ? 134 LEU C CD2 1 
ATOM   7711 N  N   . ILE D 2 139 ? -38.552 21.111  25.172  1   47.32  ? 135 ILE C N   1 
ATOM   7712 C  CA  . ILE D 2 139 ? -38.735 21.753  23.87   1   48.34  ? 135 ILE C CA  1 
ATOM   7713 C  C   . ILE D 2 139 ? -37.377 21.986  23.21   1   52.1   ? 135 ILE C C   1 
ATOM   7714 O  O   . ILE D 2 139 ? -36.385 22.262  23.887  1   54.86  ? 135 ILE C O   1 
ATOM   7715 C  CB  . ILE D 2 139 ? -39.476 23.097  24.012  1   47.31  ? 135 ILE C CB  1 
ATOM   7716 C  CG1 . ILE D 2 139 ? -38.663 24.124  24.773  1   47.44  ? 135 ILE C CG1 1 
ATOM   7717 C  CG2 . ILE D 2 139 ? -40.837 22.891  24.652  1   46.17  ? 135 ILE C CG2 1 
ATOM   7718 C  CD1 . ILE D 2 139 ? -39.293 25.497  24.806  1   50.08  ? 135 ILE C CD1 1 
ATOM   7719 N  N   . ASN D 2 140 ? -37.348 21.926  21.875  1   56.97  ? 136 ASN C N   1 
ATOM   7720 C  CA  . ASN D 2 140 ? -36.193 22.403  21.116  1   62.78  ? 136 ASN C CA  1 
ATOM   7721 C  C   . ASN D 2 140 ? -36.549 23.692  20.368  1   68.94  ? 136 ASN C C   1 
ATOM   7722 O  O   . ASN D 2 140 ? -37.699 24.162  20.403  1   75.45  ? 136 ASN C O   1 
ATOM   7723 C  CB  . ASN D 2 140 ? -35.604 21.335  20.196  1   57.12  ? 136 ASN C CB  1 
ATOM   7724 C  CG  . ASN D 2 140 ? -36.59  20.911  19.127  1   57.08  ? 136 ASN C CG  1 
ATOM   7725 O  OD1 . ASN D 2 140 ? -37.416 21.709  18.676  1   57.58  ? 136 ASN C OD1 1 
ATOM   7726 N  ND2 . ASN D 2 140 ? -36.599 19.641  18.756  1   54.8   ? 136 ASN C ND2 1 
ATOM   7727 N  N   . THR D 2 141 ? -35.547 24.203  19.636  1   68.53  ? 137 THR C N   1 
ATOM   7728 C  CA  . THR D 2 141 ? -35.593 25.481  18.939  1   70.14  ? 137 THR C CA  1 
ATOM   7729 C  C   . THR D 2 141 ? -36.302 25.368  17.59   1   75.27  ? 137 THR C C   1 
ATOM   7730 O  O   . THR D 2 141 ? -36.525 26.387  16.934  1   82.52  ? 137 THR C O   1 
ATOM   7731 C  CB  . THR D 2 141 ? -34.184 26.026  18.723  1   70.05  ? 137 THR C CB  1 
ATOM   7732 O  OG1 . THR D 2 141 ? -33.547 25.109  17.844  1   72.16  ? 137 THR C OG1 1 
ATOM   7733 C  CG2 . THR D 2 141 ? -33.378 26.133  19.999  1   71.49  ? 137 THR C CG2 1 
ATOM   7734 N  N   . GLU D 2 142 ? -36.635 24.14   17.172  1   74.7   ? 138 GLU C N   1 
ATOM   7735 C  CA  . GLU D 2 142 ? -37.305 23.926  15.9    1   76.23  ? 138 GLU C CA  1 
ATOM   7736 C  C   . GLU D 2 142 ? -38.794 23.647  16.083  1   71.81  ? 138 GLU C C   1 
ATOM   7737 O  O   . GLU D 2 142 ? -39.416 23.116  15.176  1   73.2   ? 138 GLU C O   1 
ATOM   7738 C  CB  . GLU D 2 142 ? -36.629 22.793  15.135  1   83.38  ? 138 GLU C CB  1 
ATOM   7739 C  CG  . GLU D 2 142 ? -35.163 23.078  14.824  1   94.8   ? 138 GLU C CG  1 
ATOM   7740 C  CD  . GLU D 2 142 ? -34.632 22.255  13.665  1   102.37 ? 138 GLU C CD  1 
ATOM   7741 O  OE1 . GLU D 2 142 ? -34.767 21.014  13.711  1   104.76 ? 138 GLU C OE1 1 
ATOM   7742 O  OE2 . GLU D 2 142 ? -34.091 22.856  12.712  1   110.83 ? 138 GLU C OE2 1 
ATOM   7743 N  N   . GLY D 2 143 ? -39.35  23.992  17.249  1   68.9   ? 139 GLY C N   1 
ATOM   7744 C  CA  . GLY D 2 143 ? -40.787 23.983  17.477  1   68.17  ? 139 GLY C CA  1 
ATOM   7745 C  C   . GLY D 2 143 ? -41.34  22.636  17.951  1   66.74  ? 139 GLY C C   1 
ATOM   7746 O  O   . GLY D 2 143 ? -42.559 22.462  17.961  1   66.9   ? 139 GLY C O   1 
ATOM   7747 N  N   . ALA D 2 144 ? -40.471 21.693  18.36   1   61.73  ? 140 ALA C N   1 
ATOM   7748 C  CA  . ALA D 2 144 ? -40.927 20.427  18.92   1   57.65  ? 140 ALA C CA  1 
ATOM   7749 C  C   . ALA D 2 144 ? -41.129 20.517  20.435  1   57.88  ? 140 ALA C C   1 
ATOM   7750 O  O   . ALA D 2 144 ? -40.52  21.371  21.1    1   57.91  ? 140 ALA C O   1 
ATOM   7751 C  CB  . ALA D 2 144 ? -39.919 19.363  18.614  1   55.85  ? 140 ALA C CB  1 
ATOM   7752 N  N   . ILE D 2 145 ? -41.973 19.606  20.957  1   54.42  ? 141 ILE C N   1 
ATOM   7753 C  CA  . ILE D 2 145 ? -42.04  19.317  22.389  1   53.78  ? 141 ILE C CA  1 
ATOM   7754 C  C   . ILE D 2 145 ? -42.092 17.805  22.602  1   54.96  ? 141 ILE C C   1 
ATOM   7755 O  O   . ILE D 2 145 ? -42.709 17.104  21.806  1   58     ? 141 ILE C O   1 
ATOM   7756 C  CB  . ILE D 2 145 ? -43.247 20.005  23.05   1   50.17  ? 141 ILE C CB  1 
ATOM   7757 C  CG1 . ILE D 2 145 ? -43.185 19.941  24.57   1   48.22  ? 141 ILE C CG1 1 
ATOM   7758 C  CG2 . ILE D 2 145 ? -44.553 19.43   22.523  1   50.29  ? 141 ILE C CG2 1 
ATOM   7759 C  CD1 . ILE D 2 145 ? -44.168 20.878  25.263  1   46.92  ? 141 ILE C CD1 1 
ATOM   7760 N  N   . LYS D 2 146 ? -41.498 17.331  23.704  1   52.65  ? 142 LYS C N   1 
ATOM   7761 C  CA  . LYS D 2 146 ? -41.4   15.906  23.99   1   52.06  ? 142 LYS C CA  1 
ATOM   7762 C  C   . LYS D 2 146 ? -41.613 15.577  25.476  1   49.74  ? 142 LYS C C   1 
ATOM   7763 O  O   . LYS D 2 146 ? -41.101 16.282  26.344  1   48.63  ? 142 LYS C O   1 
ATOM   7764 C  CB  . LYS D 2 146 ? -40.005 15.409  23.584  1   51.52  ? 142 LYS C CB  1 
ATOM   7765 C  CG  . LYS D 2 146 ? -39.676 15.613  22.134  1   53.84  ? 142 LYS C CG  1 
ATOM   7766 C  CD  . LYS D 2 146 ? -38.463 14.801  21.693  1   55.88  ? 142 LYS C CD  1 
ATOM   7767 C  CE  . LYS D 2 146 ? -37.916 15.234  20.337  1   52.87  ? 142 LYS C CE  1 
ATOM   7768 N  NZ  . LYS D 2 146 ? -37.17  14.139  19.719  1   47.57  ? 142 LYS C NZ  1 
ATOM   7769 N  N   . LEU D 2 147 ? -42.317 14.462  25.76   1   48.3   ? 143 LEU C N   1 
ATOM   7770 C  CA  . LEU D 2 147 ? -42.425 13.883  27.097  1   48.03  ? 143 LEU C CA  1 
ATOM   7771 C  C   . LEU D 2 147 ? -41.051 13.408  27.563  1   48.66  ? 143 LEU C C   1 
ATOM   7772 O  O   . LEU D 2 147 ? -40.352 12.733  26.818  1   53.19  ? 143 LEU C O   1 
ATOM   7773 C  CB  . LEU D 2 147 ? -43.357 12.671  27.158  1   47.56  ? 143 LEU C CB  1 
ATOM   7774 C  CG  . LEU D 2 147 ? -44.74  12.737  26.505  1   49.77  ? 143 LEU C CG  1 
ATOM   7775 C  CD1 . LEU D 2 147 ? -45.524 11.515  26.99   1   49.14  ? 143 LEU C CD1 1 
ATOM   7776 C  CD2 . LEU D 2 147 ? -45.455 14.034  26.809  1   48.96  ? 143 LEU C CD2 1 
ATOM   7777 N  N   . ALA D 2 148 ? -40.75  13.608  28.847  1   48.18  ? 144 ALA C N   1 
ATOM   7778 C  CA  . ALA D 2 148 ? -39.459 13.158  29.416  1   47.71  ? 144 ALA C CA  1 
ATOM   7779 C  C   . ALA D 2 148 ? -39.607 12.699  30.867  1   47.58  ? 144 ALA C C   1 
ATOM   7780 O  O   . ALA D 2 148 ? -40.734 12.712  31.374  1   50.78  ? 144 ALA C O   1 
ATOM   7781 C  CB  . ALA D 2 148 ? -38.453 14.266  29.314  1   47.51  ? 144 ALA C CB  1 
ATOM   7782 N  N   . ASP D 2 149 ? -38.502 12.305  31.5    1   52.06  ? 145 ASP C N   1 
ATOM   7783 C  CA  . ASP D 2 149 ? -38.49  11.809  32.91   1   54.86  ? 145 ASP C CA  1 
ATOM   7784 C  C   . ASP D 2 149 ? -39.506 10.682  33.105  1   53.59  ? 145 ASP C C   1 
ATOM   7785 O  O   . ASP D 2 149 ? -40.564 10.931  33.698  1   53.65  ? 145 ASP C O   1 
ATOM   7786 C  CB  . ASP D 2 149 ? -38.613 12.935  33.921  1   59.54  ? 145 ASP C CB  1 
ATOM   7787 C  CG  . ASP D 2 149 ? -37.999 12.654  35.283  1   78.94  ? 145 ASP C CG  1 
ATOM   7788 O  OD1 . ASP D 2 149 ? -37.6   11.494  35.52   1   76.9   ? 145 ASP C OD1 1 
ATOM   7789 O  OD2 . ASP D 2 149 ? -37.928 13.597  36.097  1   83.15  ? 145 ASP C OD2 1 
ATOM   7790 N  N   . PHE D 2 150 ? -39.15  9.475   32.682  1   49.17  ? 146 PHE C N   1 
ATOM   7791 C  CA  . PHE D 2 150 ? -40.085 8.327   32.772  1   48.92  ? 146 PHE C CA  1 
ATOM   7792 C  C   . PHE D 2 150 ? -39.695 7.457   33.951  1   51.65  ? 146 PHE C C   1 
ATOM   7793 O  O   . PHE D 2 150 ? -39.891 6.239   33.896  1   51.65  ? 146 PHE C O   1 
ATOM   7794 C  CB  . PHE D 2 150 ? -40.038 7.563   31.45   1   45.89  ? 146 PHE C CB  1 
ATOM   7795 C  CG  . PHE D 2 150 ? -40.861 8.135   30.306  1   44.91  ? 146 PHE C CG  1 
ATOM   7796 C  CD1 . PHE D 2 150 ? -40.477 9.303   29.663  1   42.62  ? 146 PHE C CD1 1 
ATOM   7797 C  CD2 . PHE D 2 150 ? -42.006 7.485   29.864  1   45.57  ? 146 PHE C CD2 1 
ATOM   7798 C  CE1 . PHE D 2 150 ? -41.225 9.812   28.616  1   44.07  ? 146 PHE C CE1 1 
ATOM   7799 C  CE2 . PHE D 2 150 ? -42.749 7.999   28.816  1   44.11  ? 146 PHE C CE2 1 
ATOM   7800 C  CZ  . PHE D 2 150 ? -42.358 9.159   28.196  1   44.07  ? 146 PHE C CZ  1 
ATOM   7801 N  N   . GLY D 2 151 ? -39.17  8.073   35.006  1   53.79  ? 147 GLY C N   1 
ATOM   7802 C  CA  . GLY D 2 151 ? -38.745 7.323   36.2    1   53.85  ? 147 GLY C CA  1 
ATOM   7803 C  C   . GLY D 2 151 ? -39.914 6.93    37.068  1   53.81  ? 147 GLY C C   1 
ATOM   7804 O  O   . GLY D 2 151 ? -39.815 5.907   37.759  1   54.47  ? 147 GLY C O   1 
ATOM   7805 N  N   . LEU D 2 152 ? -40.991 7.707   37.021  1   56.08  ? 148 LEU C N   1 
ATOM   7806 C  CA  . LEU D 2 152 ? -42.203 7.407   37.813  1   54.32  ? 148 LEU C CA  1 
ATOM   7807 C  C   . LEU D 2 152 ? -43.22  6.711   36.909  1   52.18  ? 148 LEU C C   1 
ATOM   7808 O  O   . LEU D 2 152 ? -44.409 6.702   37.252  1   53.27  ? 148 LEU C O   1 
ATOM   7809 C  CB  . LEU D 2 152 ? -42.717 8.745   38.33   1   61.27  ? 148 LEU C CB  1 
ATOM   7810 C  CG  . LEU D 2 152 ? -41.814 9.489   39.314  1   66.15  ? 148 LEU C CG  1 
ATOM   7811 C  CD1 . LEU D 2 152 ? -40.435 9.628   38.705  1   72.73  ? 148 LEU C CD1 1 
ATOM   7812 C  CD2 . LEU D 2 152 ? -42.41  10.854  39.602  1   61.76  ? 148 LEU C CD2 1 
ATOM   7813 N  N   . ALA D 2 153 ? -42.754 6.133   35.808  1   50.23  ? 149 ALA C N   1 
ATOM   7814 C  CA  . ALA D 2 153 ? -43.67  5.518   34.827  1   47.84  ? 149 ALA C CA  1 
ATOM   7815 C  C   . ALA D 2 153 ? -43.939 4.056   35.164  1   50.52  ? 149 ALA C C   1 
ATOM   7816 O  O   . ALA D 2 153 ? -43.159 3.438   35.899  1   53.38  ? 149 ALA C O   1 
ATOM   7817 C  CB  . ALA D 2 153 ? -43.087 5.661   33.45   1   44.43  ? 149 ALA C CB  1 
ATOM   7818 N  N   . ARG D 2 154 ? -45.03  3.517   34.627  1   51.77  ? 150 ARG C N   1 
ATOM   7819 C  CA  . ARG D 2 154 ? -45.389 2.112   34.915  1   54.53  ? 150 ARG C CA  1 
ATOM   7820 C  C   . ARG D 2 154 ? -45.994 1.415   33.702  1   53.8   ? 150 ARG C C   1 
ATOM   7821 O  O   . ARG D 2 154 ? -46.866 2.01    33.054  1   56.97  ? 150 ARG C O   1 
ATOM   7822 C  CB  . ARG D 2 154 ? -46.461 2.002   36.002  1   56.73  ? 150 ARG C CB  1 
ATOM   7823 C  CG  . ARG D 2 154 ? -46.812 0.601   36.481  1   57.04  ? 150 ARG C CG  1 
ATOM   7824 C  CD  . ARG D 2 154 ? -45.95  0.177   37.655  1   57.35  ? 150 ARG C CD  1 
ATOM   7825 N  NE  . ARG D 2 154 ? -46.416 -1.044  38.322  1   53.9   ? 150 ARG C NE  1 
ATOM   7826 C  CZ  . ARG D 2 154 ? -46.631 -1.125  39.625  1   51.31  ? 150 ARG C CZ  1 
ATOM   7827 N  NH1 . ARG D 2 154 ? -47.701 -0.587  40.159  1   50.19  ? 150 ARG C NH1 1 
ATOM   7828 N  NH2 . ARG D 2 154 ? -45.766 -1.705  40.421  1   50.25  ? 150 ARG C NH2 1 
ATOM   7829 N  N   . ALA D 2 155 ? -45.498 0.226   33.38   1   51.28  ? 151 ALA C N   1 
ATOM   7830 C  CA  . ALA D 2 155 ? -46.153 -0.593  32.368  1   50.21  ? 151 ALA C CA  1 
ATOM   7831 C  C   . ALA D 2 155 ? -47.398 -1.218  32.99   1   53.36  ? 151 ALA C C   1 
ATOM   7832 O  O   . ALA D 2 155 ? -47.303 -1.951  33.968  1   56.5   ? 151 ALA C O   1 
ATOM   7833 C  CB  . ALA D 2 155 ? -45.209 -1.656  31.851  1   47.23  ? 151 ALA C CB  1 
ATOM   7834 N  N   . PHE D 2 156 ? -48.577 -0.898  32.456  1   53.99  ? 152 PHE C N   1 
ATOM   7835 C  CA  . PHE D 2 156 ? -49.805 -1.385  33.065  1   57.79  ? 152 PHE C CA  1 
ATOM   7836 C  C   . PHE D 2 156 ? -50.296 -2.631  32.331  1   59.99  ? 152 PHE C C   1 
ATOM   7837 O  O   . PHE D 2 156 ? -49.88  -2.886  31.202  1   59.26  ? 152 PHE C O   1 
ATOM   7838 C  CB  . PHE D 2 156 ? -50.877 -0.288  33.165  1   56.59  ? 152 PHE C CB  1 
ATOM   7839 C  CG  . PHE D 2 156 ? -51.418 0.258   31.856  1   56.59  ? 152 PHE C CG  1 
ATOM   7840 C  CD1 . PHE D 2 156 ? -50.788 1.327   31.222  1   54.34  ? 152 PHE C CD1 1 
ATOM   7841 C  CD2 . PHE D 2 156 ? -52.571 -0.283  31.281  1   57.73  ? 152 PHE C CD2 1 
ATOM   7842 C  CE1 . PHE D 2 156 ? -51.291 1.836   30.031  1   55.69  ? 152 PHE C CE1 1 
ATOM   7843 C  CE2 . PHE D 2 156 ? -53.074 0.228   30.088  1   57.49  ? 152 PHE C CE2 1 
ATOM   7844 C  CZ  . PHE D 2 156 ? -52.443 1.294   29.47   1   57.38  ? 152 PHE C CZ  1 
ATOM   7845 N  N   . GLY D 2 157 ? -51.167 -3.398  33.009  1   62.48  ? 153 GLY C N   1 
ATOM   7846 C  CA  . GLY D 2 157 ? -51.907 -4.508  32.421  1   65.72  ? 153 GLY C CA  1 
ATOM   7847 C  C   . GLY D 2 157 ? -53.362 -4.119  32.137  1   69.74  ? 153 GLY C C   1 
ATOM   7848 O  O   . GLY D 2 157 ? -53.786 -3.013  32.486  1   73.25  ? 153 GLY C O   1 
ATOM   7849 N  N   . VAL D 2 158 ? -54.132 -5.024  31.511  1   69.11  ? 154 VAL C N   1 
ATOM   7850 C  CA  . VAL D 2 158 ? -55.521 -4.741  31.164  1   70.1   ? 154 VAL C CA  1 
ATOM   7851 C  C   . VAL D 2 158 ? -56.42  -5.838  31.748  1   72.79  ? 154 VAL C C   1 
ATOM   7852 O  O   . VAL D 2 158 ? -56.231 -7.01   31.443  1   75.93  ? 154 VAL C O   1 
ATOM   7853 C  CB  . VAL D 2 158 ? -55.704 -4.58   29.639  1   69.34  ? 154 VAL C CB  1 
ATOM   7854 C  CG1 . VAL D 2 158 ? -57.11  -4.136  29.273  1   71.62  ? 154 VAL C CG1 1 
ATOM   7855 C  CG2 . VAL D 2 158 ? -54.688 -3.623  29.026  1   64.84  ? 154 VAL C CG2 1 
ATOM   7856 N  N   . PRO D 2 159 ? -57.387 -5.542  32.654  1   73.69  ? 155 PRO C N   1 
ATOM   7857 C  CA  . PRO D 2 159 ? -57.603 -4.192  33.193  1   72.12  ? 155 PRO C CA  1 
ATOM   7858 C  C   . PRO D 2 159 ? -56.47  -3.783  34.131  1   69.91  ? 155 PRO C C   1 
ATOM   7859 O  O   . PRO D 2 159 ? -55.651 -4.617  34.512  1   70.09  ? 155 PRO C O   1 
ATOM   7860 C  CB  . PRO D 2 159 ? -58.926 -4.302  33.962  1   72.97  ? 155 PRO C CB  1 
ATOM   7861 C  CG  . PRO D 2 159 ? -59.031 -5.769  34.331  1   75.31  ? 155 PRO C CG  1 
ATOM   7862 C  CD  . PRO D 2 159 ? -58.306 -6.539  33.233  1   75.54  ? 155 PRO C CD  1 
ATOM   7863 N  N   . VAL D 2 160 ? -56.427 -2.498  34.494  1   67.88  ? 156 VAL C N   1 
ATOM   7864 C  CA  . VAL D 2 160 ? -55.406 -2.018  35.408  1   65.36  ? 156 VAL C CA  1 
ATOM   7865 C  C   . VAL D 2 160 ? -55.695 -2.628  36.772  1   69.95  ? 156 VAL C C   1 
ATOM   7866 O  O   . VAL D 2 160 ? -56.861 -2.889  37.09   1   75.03  ? 156 VAL C O   1 
ATOM   7867 C  CB  . VAL D 2 160 ? -55.354 -0.481  35.488  1   60.71  ? 156 VAL C CB  1 
ATOM   7868 C  CG1 . VAL D 2 160 ? -55.124 0.147   34.124  1   59.3   ? 156 VAL C CG1 1 
ATOM   7869 C  CG2 . VAL D 2 160 ? -56.589 0.103   36.142  1   60.55  ? 156 VAL C CG2 1 
ATOM   7870 N  N   . ARG D 2 161 ? -54.628 -2.86   37.549  1   71.02  ? 157 ARG C N   1 
ATOM   7871 C  CA  . ARG D 2 161 ? -54.751 -3.232  38.955  1   78.15  ? 157 ARG C CA  1 
ATOM   7872 C  C   . ARG D 2 161 ? -54.225 -2.092  39.837  1   75.11  ? 157 ARG C C   1 
ATOM   7873 O  O   . ARG D 2 161 ? -53.919 -1.014  39.327  1   75.01  ? 157 ARG C O   1 
ATOM   7874 C  CB  . ARG D 2 161 ? -54.108 -4.594  39.262  1   80.81  ? 157 ARG C CB  1 
ATOM   7875 C  CG  . ARG D 2 161 ? -52.587 -4.571  39.257  1   81.6   ? 157 ARG C CG  1 
ATOM   7876 C  CD  . ARG D 2 161 ? -52.061 -5.566  40.275  1   87.76  ? 157 ARG C CD  1 
ATOM   7877 N  NE  . ARG D 2 161 ? -50.73  -5.156  40.746  1   90.55  ? 157 ARG C NE  1 
ATOM   7878 C  CZ  . ARG D 2 161 ? -49.604 -5.251  40.063  1   82.92  ? 157 ARG C CZ  1 
ATOM   7879 N  NH1 . ARG D 2 161 ? -49.57  -5.991  38.966  1   80.61  ? 157 ARG C NH1 1 
ATOM   7880 N  NH2 . ARG D 2 161 ? -48.525 -4.639  40.517  1   77.4   ? 157 ARG C NH2 1 
ATOM   7881 N  N   . THR D 2 162 ? -54.12  -2.336  41.155  1   73.53  ? 158 THR C N   1 
ATOM   7882 C  CA  . THR D 2 162 ? -53.694 -1.288  42.069  1   71.96  ? 158 THR C CA  1 
ATOM   7883 C  C   . THR D 2 162 ? -52.207 -1.01   41.853  1   69.86  ? 158 THR C C   1 
ATOM   7884 O  O   . THR D 2 162 ? -51.385 -1.939  41.894  1   71.89  ? 158 THR C O   1 
ATOM   7885 C  CB  . THR D 2 162 ? -54.019 -1.641  43.521  1   73.25  ? 158 THR C CB  1 
ATOM   7886 O  OG1 . THR D 2 162 ? -55.438 -1.578  43.553  1   78.59  ? 158 THR C OG1 1 
ATOM   7887 C  CG2 . THR D 2 162 ? -53.462 -0.649  44.529  1   68.71  ? 158 THR C CG2 1 
ATOM   7888 N  N   . TYR D 2 163 ? -51.904 0.278   41.619  1   63.89  ? 159 TYR C N   1 
ATOM   7889 C  CA  . TYR D 2 163 ? -50.55  0.748   41.407  1   62.14  ? 159 TYR C CA  1 
ATOM   7890 C  C   . TYR D 2 163 ? -50.155 1.616   42.593  1   64.38  ? 159 TYR C C   1 
ATOM   7891 O  O   . TYR D 2 163 ? -50.913 1.714   43.557  1   67.49  ? 159 TYR C O   1 
ATOM   7892 C  CB  . TYR D 2 163 ? -50.472 1.435   40.043  1   62.48  ? 159 TYR C CB  1 
ATOM   7893 C  CG  . TYR D 2 163 ? -50.787 0.516   38.869  1   65.78  ? 159 TYR C CG  1 
ATOM   7894 C  CD1 . TYR D 2 163 ? -50.364 -0.807  38.873  1   65.71  ? 159 TYR C CD1 1 
ATOM   7895 C  CD2 . TYR D 2 163 ? -51.519 0.958   37.772  1   63.51  ? 159 TYR C CD2 1 
ATOM   7896 C  CE1 . TYR D 2 163 ? -50.658 -1.664  37.831  1   66     ? 159 TYR C CE1 1 
ATOM   7897 C  CE2 . TYR D 2 163 ? -51.797 0.11    36.717  1   62.22  ? 159 TYR C CE2 1 
ATOM   7898 C  CZ  . TYR D 2 163 ? -51.377 -1.208  36.749  1   64.52  ? 159 TYR C CZ  1 
ATOM   7899 O  OH  . TYR D 2 163 ? -51.634 -2.121  35.757  1   71.01  ? 159 TYR C OH  1 
HETATM 7900 N  N   . TPO D 2 164 ? -48.964 2.212   42.52   1   64.14  ? 160 TPO C N   1 
HETATM 7901 C  CA  . TPO D 2 164 ? -48.474 3.101   43.604  1   64.66  ? 160 TPO C CA  1 
HETATM 7902 C  CB  . TPO D 2 164 ? -47.001 3.465   43.39   1   61.67  ? 160 TPO C CB  1 
HETATM 7903 C  CG2 . TPO D 2 164 ? -46.396 4.153   44.59   1   59.52  ? 160 TPO C CG2 1 
HETATM 7904 O  OG1 . TPO D 2 164 ? -46.258 2.224   43.165  1   60.11  ? 160 TPO C OG1 1 
HETATM 7905 P  P   . TPO D 2 164 ? -45.638 1.904   41.722  1   57.72  ? 160 TPO C P   1 
HETATM 7906 O  O1P . TPO D 2 164 ? -46.82  1.611   40.838  1   60.07  ? 160 TPO C O1P 1 
HETATM 7907 O  O2P . TPO D 2 164 ? -44.732 0.717   41.909  1   55.11  ? 160 TPO C O2P 1 
HETATM 7908 O  O3P . TPO D 2 164 ? -44.896 3.146   41.307  1   56.13  ? 160 TPO C O3P 1 
HETATM 7909 C  C   . TPO D 2 164 ? -49.371 4.337   43.673  1   71.66  ? 160 TPO C C   1 
HETATM 7910 O  O   . TPO D 2 164 ? -49.702 4.865   42.61   1   71.21  ? 160 TPO C O   1 
ATOM   7911 N  N   . HIS D 2 165 ? -49.748 4.767   44.879  1   79.87  ? 161 HIS C N   1 
ATOM   7912 C  CA  . HIS D 2 165 ? -50.684 5.908   45.046  1   85.25  ? 161 HIS C CA  1 
ATOM   7913 C  C   . HIS D 2 165 ? -49.912 7.223   45.05   1   86.58  ? 161 HIS C C   1 
ATOM   7914 O  O   . HIS D 2 165 ? -50.392 8.226   44.495  1   86.08  ? 161 HIS C O   1 
ATOM   7915 C  CB  . HIS D 2 165 ? -51.456 5.777   46.359  1   88.37  ? 161 HIS C CB  1 
ATOM   7916 C  CG  . HIS D 2 165 ? -51.914 7.08    46.924  1   98.53  ? 161 HIS C CG  1 
ATOM   7917 N  ND1 . HIS D 2 165 ? -53.025 7.745   46.455  1   101.68 ? 161 HIS C ND1 1 
ATOM   7918 C  CD2 . HIS D 2 165 ? -51.413 7.841   47.904  1   100.55 ? 161 HIS C CD2 1 
ATOM   7919 C  CE1 . HIS D 2 165 ? -53.179 8.869   47.138  1   103.8  ? 161 HIS C CE1 1 
ATOM   7920 N  NE2 . HIS D 2 165 ? -52.211 8.947   48.022  1   100.33 ? 161 HIS C NE2 1 
ATOM   7921 N  N   . GLU D 2 166 ? -48.749 7.221   45.686  1   86     ? 162 GLU C N   1 
ATOM   7922 C  CA  . GLU D 2 166 ? -47.916 8.444   45.731  1   87.43  ? 162 GLU C CA  1 
ATOM   7923 C  C   . GLU D 2 166 ? -47.452 8.751   44.305  1   89.11  ? 162 GLU C C   1 
ATOM   7924 O  O   . GLU D 2 166 ? -46.279 8.468   44.002  1   97.74  ? 162 GLU C O   1 
ATOM   7925 C  CB  . GLU D 2 166 ? -46.74  8.213   46.677  1   81.76  ? 162 GLU C CB  1 
ATOM   7926 C  CG  . GLU D 2 166 ? -47.167 7.765   48.072  1   90.94  ? 162 GLU C CG  1 
ATOM   7927 C  CD  . GLU D 2 166 ? -47.399 6.274   48.241  1   95.83  ? 162 GLU C CD  1 
ATOM   7928 O  OE1 . GLU D 2 166 ? -48.515 5.899   48.653  1   96.09  ? 162 GLU C OE1 1 
ATOM   7929 O  OE2 . GLU D 2 166 ? -46.473 5.489   47.953  1   94.39  ? 162 GLU C OE2 1 
ATOM   7930 N  N   . VAL D 2 167 ? -48.331 9.303   43.466  1   80.57  ? 163 VAL C N   1 
ATOM   7931 C  CA  . VAL D 2 167 ? -47.947 9.51    42.04   1   77.31  ? 163 VAL C CA  1 
ATOM   7932 C  C   . VAL D 2 167 ? -48.401 10.895  41.563  1   75.61  ? 163 VAL C C   1 
ATOM   7933 O  O   . VAL D 2 167 ? -49.479 11.328  42.011  1   80.42  ? 163 VAL C O   1 
ATOM   7934 C  CB  . VAL D 2 167 ? -48.47  8.395   41.11   1   73.5   ? 163 VAL C CB  1 
ATOM   7935 C  CG1 . VAL D 2 167 ? -47.631 7.128   41.206  1   66.66  ? 163 VAL C CG1 1 
ATOM   7936 C  CG2 . VAL D 2 167 ? -49.946 8.094   41.323  1   69.92  ? 163 VAL C CG2 1 
ATOM   7937 N  N   . VAL D 2 168 ? -47.601 11.551  40.722  1   66.37  ? 164 VAL C N   1 
ATOM   7938 C  CA  . VAL D 2 168 ? -47.911 12.885  40.112  1   62.61  ? 164 VAL C CA  1 
ATOM   7939 C  C   . VAL D 2 168 ? -47.733 14.013  41.138  1   61.77  ? 164 VAL C C   1 
ATOM   7940 O  O   . VAL D 2 168 ? -48.329 13.937  42.221  1   58.66  ? 164 VAL C O   1 
ATOM   7941 C  CB  . VAL D 2 168 ? -49.269 13.044  39.388  1   63.72  ? 164 VAL C CB  1 
ATOM   7942 C  CG1 . VAL D 2 168 ? -49.233 14.194  38.394  1   62.52  ? 164 VAL C CG1 1 
ATOM   7943 C  CG2 . VAL D 2 168 ? -49.734 11.773  38.688  1   62.04  ? 164 VAL C CG2 1 
ATOM   7944 N  N   . THR D 2 169 ? -46.926 15.017  40.8    1   62.57  ? 165 THR C N   1 
ATOM   7945 C  CA  . THR D 2 169 ? -46.805 16.209  41.638  1   61.28  ? 165 THR C CA  1 
ATOM   7946 C  C   . THR D 2 169 ? -48.211 16.754  41.935  1   61.39  ? 165 THR C C   1 
ATOM   7947 O  O   . THR D 2 169 ? -49.082 16.769  41.047  1   56.61  ? 165 THR C O   1 
ATOM   7948 C  CB  . THR D 2 169 ? -45.926 17.238  40.919  1   60.35  ? 165 THR C CB  1 
ATOM   7949 O  OG1 . THR D 2 169 ? -44.737 16.548  40.541  1   62.31  ? 165 THR C OG1 1 
ATOM   7950 C  CG2 . THR D 2 169 ? -45.668 18.498  41.732  1   60.34  ? 165 THR C CG2 1 
ATOM   7951 N  N   . LEU D 2 170 ? -48.399 17.235  43.179  1   60.02  ? 166 LEU C N   1 
ATOM   7952 C  CA  . LEU D 2 170 ? -49.709 17.556  43.731  1   60.92  ? 166 LEU C CA  1 
ATOM   7953 C  C   . LEU D 2 170 ? -50.595 18.316  42.736  1   61.4   ? 166 LEU C C   1 
ATOM   7954 O  O   . LEU D 2 170 ? -51.74  17.939  42.482  1   63.81  ? 166 LEU C O   1 
ATOM   7955 C  CB  . LEU D 2 170 ? -49.522 18.354  45.021  1   59.93  ? 166 LEU C CB  1 
ATOM   7956 C  CG  . LEU D 2 170 ? -50.807 18.877  45.675  1   61.67  ? 166 LEU C CG  1 
ATOM   7957 C  CD1 . LEU D 2 170 ? -51.815 17.77   45.981  1   60.97  ? 166 LEU C CD1 1 
ATOM   7958 C  CD2 . LEU D 2 170 ? -50.494 19.657  46.938  1   62.23  ? 166 LEU C CD2 1 
ATOM   7959 N  N   . TRP D 2 171 ? -50.057 19.413  42.201  1   60.19  ? 167 TRP C N   1 
ATOM   7960 C  CA  . TRP D 2 171 ? -50.783 20.339  41.348  1   58.26  ? 167 TRP C CA  1 
ATOM   7961 C  C   . TRP D 2 171 ? -51.38  19.652  40.119  1   59.08  ? 167 TRP C C   1 
ATOM   7962 O  O   . TRP D 2 171 ? -52.31  20.177  39.528  1   61.43  ? 167 TRP C O   1 
ATOM   7963 C  CB  . TRP D 2 171 ? -49.814 21.44   40.918  1   55.99  ? 167 TRP C CB  1 
ATOM   7964 C  CG  . TRP D 2 171 ? -49.379 22.346  42.033  1   57.67  ? 167 TRP C CG  1 
ATOM   7965 C  CD1 . TRP D 2 171 ? -49.716 22.278  43.355  1   60.28  ? 167 TRP C CD1 1 
ATOM   7966 C  CD2 . TRP D 2 171 ? -48.528 23.497  41.899  1   57.28  ? 167 TRP C CD2 1 
ATOM   7967 N  NE1 . TRP D 2 171 ? -49.154 23.312  44.055  1   58.77  ? 167 TRP C NE1 1 
ATOM   7968 C  CE2 . TRP D 2 171 ? -48.424 24.082  43.186  1   59.64  ? 167 TRP C CE2 1 
ATOM   7969 C  CE3 . TRP D 2 171 ? -47.861 24.093  40.824  1   55.44  ? 167 TRP C CE3 1 
ATOM   7970 C  CZ2 . TRP D 2 171 ? -47.667 25.231  43.415  1   59.32  ? 167 TRP C CZ2 1 
ATOM   7971 C  CZ3 . TRP D 2 171 ? -47.123 25.234  41.057  1   56.22  ? 167 TRP C CZ3 1 
ATOM   7972 C  CH2 . TRP D 2 171 ? -47.038 25.795  42.328  1   57.2   ? 167 TRP C CH2 1 
ATOM   7973 N  N   . TYR D 2 172 ? -50.833 18.498  39.713  1   57.92  ? 168 TYR C N   1 
ATOM   7974 C  CA  . TYR D 2 172 ? -51.183 17.878  38.442  1   54.24  ? 168 TYR C CA  1 
ATOM   7975 C  C   . TYR D 2 172 ? -51.924 16.569  38.69   1   55.29  ? 168 TYR C C   1 
ATOM   7976 O  O   . TYR D 2 172 ? -52.267 15.878  37.728  1   55.19  ? 168 TYR C O   1 
ATOM   7977 C  CB  . TYR D 2 172 ? -49.902 17.683  37.619  1   50.01  ? 168 TYR C CB  1 
ATOM   7978 C  CG  . TYR D 2 172 ? -49.285 19.037  37.307  1   49.78  ? 168 TYR C CG  1 
ATOM   7979 C  CD1 . TYR D 2 172 ? -49.745 19.798  36.233  1   48.22  ? 168 TYR C CD1 1 
ATOM   7980 C  CD2 . TYR D 2 172 ? -48.325 19.592  38.149  1   48.05  ? 168 TYR C CD2 1 
ATOM   7981 C  CE1 . TYR D 2 172 ? -49.217 21.048  35.966  1   48.31  ? 168 TYR C CE1 1 
ATOM   7982 C  CE2 . TYR D 2 172 ? -47.815 20.852  37.899  1   48.17  ? 168 TYR C CE2 1 
ATOM   7983 C  CZ  . TYR D 2 172 ? -48.261 21.582  36.808  1   48.84  ? 168 TYR C CZ  1 
ATOM   7984 O  OH  . TYR D 2 172 ? -47.762 22.827  36.551  1   50.81  ? 168 TYR C OH  1 
ATOM   7985 N  N   . ARG D 2 173 ? -52.178 16.278  39.98   1   55.45  ? 169 ARG C N   1 
ATOM   7986 C  CA  . ARG D 2 173 ? -52.752 15.026  40.449  1   56.69  ? 169 ARG C CA  1 
ATOM   7987 C  C   . ARG D 2 173 ? -54.268 15.059  40.285  1   59.48  ? 169 ARG C C   1 
ATOM   7988 O  O   . ARG D 2 173 ? -54.945 15.943  40.834  1   62.11  ? 169 ARG C O   1 
ATOM   7989 C  CB  . ARG D 2 173 ? -52.377 14.841  41.925  1   57.73  ? 169 ARG C CB  1 
ATOM   7990 C  CG  . ARG D 2 173 ? -52.642 13.447  42.476  1   59.84  ? 169 ARG C CG  1 
ATOM   7991 C  CD  . ARG D 2 173 ? -52.171 13.325  43.906  1   61.62  ? 169 ARG C CD  1 
ATOM   7992 N  NE  . ARG D 2 173 ? -50.726 13.558  43.987  1   61.53  ? 169 ARG C NE  1 
ATOM   7993 C  CZ  . ARG D 2 173 ? -50.094 13.93   45.088  1   60.89  ? 169 ARG C CZ  1 
ATOM   7994 N  NH1 . ARG D 2 173 ? -50.761 14.179  46.2    1   62.48  ? 169 ARG C NH1 1 
ATOM   7995 N  NH2 . ARG D 2 173 ? -48.787 14.06   45.074  1   60.01  ? 169 ARG C NH2 1 
ATOM   7996 N  N   . ALA D 2 174 ? -54.785 14.062  39.553  1   61.14  ? 170 ALA C N   1 
ATOM   7997 C  CA  . ALA D 2 174 ? -56.202 13.977  39.192  1   63.11  ? 170 ALA C CA  1 
ATOM   7998 C  C   . ALA D 2 174 ? -57.035 13.632  40.416  1   65.71  ? 170 ALA C C   1 
ATOM   7999 O  O   . ALA D 2 174 ? -56.554 12.952  41.312  1   69.7   ? 170 ALA C O   1 
ATOM   8000 C  CB  . ALA D 2 174 ? -56.416 12.933  38.125  1   60.45  ? 170 ALA C CB  1 
ATOM   8001 N  N   . PRO D 2 175 ? -58.32  14.037  40.47   1   68.54  ? 171 PRO C N   1 
ATOM   8002 C  CA  . PRO D 2 175 ? -59.154 13.769  41.643  1   69.55  ? 171 PRO C CA  1 
ATOM   8003 C  C   . PRO D 2 175 ? -59.291 12.318  42.124  1   73.42  ? 171 PRO C C   1 
ATOM   8004 O  O   . PRO D 2 175 ? -59.451 12.104  43.323  1   75.18  ? 171 PRO C O   1 
ATOM   8005 C  CB  . PRO D 2 175 ? -60.493 14.434  41.292  1   71.56  ? 171 PRO C CB  1 
ATOM   8006 C  CG  . PRO D 2 175 ? -60.489 14.589  39.788  1   69.77  ? 171 PRO C CG  1 
ATOM   8007 C  CD  . PRO D 2 175 ? -59.038 14.745  39.4    1   68.47  ? 171 PRO C CD  1 
ATOM   8008 N  N   . GLU D 2 176 ? -59.16  11.327  41.222  1   73.2   ? 172 GLU C N   1 
ATOM   8009 C  CA  . GLU D 2 176 ? -59.353 9.933   41.603  1   74.81  ? 172 GLU C CA  1 
ATOM   8010 C  C   . GLU D 2 176 ? -58.152 9.387   42.374  1   76.38  ? 172 GLU C C   1 
ATOM   8011 O  O   . GLU D 2 176 ? -58.259 8.313   42.975  1   78.77  ? 172 GLU C O   1 
ATOM   8012 C  CB  . GLU D 2 176 ? -59.65  9.011   40.419  1   75.5   ? 172 GLU C CB  1 
ATOM   8013 C  CG  . GLU D 2 176 ? -58.547 8.966   39.365  1   73.23  ? 172 GLU C CG  1 
ATOM   8014 C  CD  . GLU D 2 176 ? -58.739 9.887   38.172  1   75.42  ? 172 GLU C CD  1 
ATOM   8015 O  OE1 . GLU D 2 176 ? -58.384 9.478   37.037  1   73.01  ? 172 GLU C OE1 1 
ATOM   8016 O  OE2 . GLU D 2 176 ? -59.292 10.998  38.36   1   77.31  ? 172 GLU C OE2 1 
ATOM   8017 N  N   . ILE D 2 177 ? -57.003 10.082  42.277  1   75.09  ? 173 ILE C N   1 
ATOM   8018 C  CA  . ILE D 2 177 ? -55.804 9.76    43.05   1   72.4   ? 173 ILE C CA  1 
ATOM   8019 C  C   . ILE D 2 177 ? -55.892 10.44   44.415  1   76.63  ? 173 ILE C C   1 
ATOM   8020 O  O   . ILE D 2 177 ? -55.527 9.842   45.424  1   78.87  ? 173 ILE C O   1 
ATOM   8021 C  CB  . ILE D 2 177 ? -54.51  10.167  42.323  1   64.72  ? 173 ILE C CB  1 
ATOM   8022 C  CG1 . ILE D 2 177 ? -54.351 9.439   41.024  1   61.5   ? 173 ILE C CG1 1 
ATOM   8023 C  CG2 . ILE D 2 177 ? -53.275 9.975   43.206  1   63.83  ? 173 ILE C CG2 1 
ATOM   8024 C  CD1 . ILE D 2 177 ? -53.144 9.905   40.236  1   61.39  ? 173 ILE C CD1 1 
ATOM   8025 N  N   . LEU D 2 178 ? -56.329 11.705  44.426  1   77.26  ? 174 LEU C N   1 
ATOM   8026 C  CA  . LEU D 2 178 ? -56.456 12.496  45.641  1   78.25  ? 174 LEU C CA  1 
ATOM   8027 C  C   . LEU D 2 178 ? -57.36  11.783  46.641  1   80.54  ? 174 LEU C C   1 
ATOM   8028 O  O   . LEU D 2 178 ? -56.936 11.504  47.765  1   79.84  ? 174 LEU C O   1 
ATOM   8029 C  CB  . LEU D 2 178 ? -57.008 13.875  45.284  1   80.28  ? 174 LEU C CB  1 
ATOM   8030 C  CG  . LEU D 2 178 ? -56.044 14.859  44.612  1   75.55  ? 174 LEU C CG  1 
ATOM   8031 C  CD1 . LEU D 2 178 ? -56.822 16.056  44.049  1   72.94  ? 174 LEU C CD1 1 
ATOM   8032 C  CD2 . LEU D 2 178 ? -54.947 15.291  45.59   1   73.11  ? 174 LEU C CD2 1 
ATOM   8033 N  N   . LEU D 2 179 ? -58.591 11.488  46.191  1   82.95  ? 175 LEU C N   1 
ATOM   8034 C  CA  . LEU D 2 179 ? -59.635 10.806  46.952  1   84.84  ? 175 LEU C CA  1 
ATOM   8035 C  C   . LEU D 2 179 ? -59.286 9.338   47.217  1   83.81  ? 175 LEU C C   1 
ATOM   8036 O  O   . LEU D 2 179 ? -60.026 8.636   47.891  1   85.94  ? 175 LEU C O   1 
ATOM   8037 C  CB  . LEU D 2 179 ? -60.953 10.934  46.19   1   82.98  ? 175 LEU C CB  1 
ATOM   8038 C  CG  . LEU D 2 179 ? -61.389 12.367  45.873  1   83.73  ? 175 LEU C CG  1 
ATOM   8039 C  CD1 . LEU D 2 179 ? -62.555 12.433  44.909  1   83.98  ? 175 LEU C CD1 1 
ATOM   8040 C  CD2 . LEU D 2 179 ? -61.712 13.118  47.153  1   88.12  ? 175 LEU C CD2 1 
ATOM   8041 N  N   . GLY D 2 180 ? -58.174 8.862   46.65   1   81.71  ? 176 GLY C N   1 
ATOM   8042 C  CA  . GLY D 2 180 ? -57.575 7.601   47.053  1   80.45  ? 176 GLY C CA  1 
ATOM   8043 C  C   . GLY D 2 180 ? -58.299 6.381   46.484  1   82.67  ? 176 GLY C C   1 
ATOM   8044 O  O   . GLY D 2 180 ? -58.304 5.331   47.122  1   82.37  ? 176 GLY C O   1 
ATOM   8045 N  N   . CYS D 2 181 ? -58.89  6.519   45.285  1   81.49  ? 177 CYS C N   1 
ATOM   8046 C  CA  . CYS D 2 181 ? -59.589 5.414   44.645  1   81.21  ? 177 CYS C CA  1 
ATOM   8047 C  C   . CYS D 2 181 ? -58.624 4.269   44.378  1   77.93  ? 177 CYS C C   1 
ATOM   8048 O  O   . CYS D 2 181 ? -57.462 4.502   44.074  1   74.19  ? 177 CYS C O   1 
ATOM   8049 C  CB  . CYS D 2 181 ? -60.122 5.795   43.273  1   85.17  ? 177 CYS C CB  1 
ATOM   8050 S  SG  . CYS D 2 181 ? -61.336 7.14    43.302  1   96.55  ? 177 CYS C SG  1 
ATOM   8051 N  N   . LYS D 2 182 ? -59.147 3.043   44.45   1   79.79  ? 178 LYS C N   1 
ATOM   8052 C  CA  . LYS D 2 182 ? -58.346 1.829   44.425  1   81.03  ? 178 LYS C CA  1 
ATOM   8053 C  C   . LYS D 2 182 ? -57.599 1.692   43.1    1   79.06  ? 178 LYS C C   1 
ATOM   8054 O  O   . LYS D 2 182 ? -56.436 1.28    43.079  1   79.8   ? 178 LYS C O   1 
ATOM   8055 C  CB  . LYS D 2 182 ? -59.246 0.605   44.633  1   84.8   ? 178 LYS C CB  1 
ATOM   8056 C  CG  . LYS D 2 182 ? -58.534 -0.657  45.1    1   83.57  ? 178 LYS C CG  1 
ATOM   8057 C  CD  . LYS D 2 182 ? -59.488 -1.836  45.241  1   86.24  ? 178 LYS C CD  1 
ATOM   8058 C  CE  . LYS D 2 182 ? -58.775 -3.143  45.403  1   86.5   ? 178 LYS C CE  1 
ATOM   8059 N  NZ  . LYS D 2 182 ? -59.756 -4.236  45.398  1   89     ? 178 LYS C NZ  1 
ATOM   8060 N  N   . TYR D 2 183 ? -58.285 2.021   41.999  1   78     ? 179 TYR C N   1 
ATOM   8061 C  CA  . TYR D 2 183 ? -57.744 1.829   40.664  1   74.85  ? 179 TYR C CA  1 
ATOM   8062 C  C   . TYR D 2 183 ? -57.713 3.17    39.939  1   73.24  ? 179 TYR C C   1 
ATOM   8063 O  O   . TYR D 2 183 ? -58.657 3.957   40.062  1   78.28  ? 179 TYR C O   1 
ATOM   8064 C  CB  . TYR D 2 183 ? -58.612 0.881   39.826  1   76.82  ? 179 TYR C CB  1 
ATOM   8065 C  CG  . TYR D 2 183 ? -58.832 -0.55   40.311  1   80.64  ? 179 TYR C CG  1 
ATOM   8066 C  CD1 . TYR D 2 183 ? -57.821 -1.303  40.912  1   80.06  ? 179 TYR C CD1 1 
ATOM   8067 C  CD2 . TYR D 2 183 ? -60.058 -1.168  40.115  1   81.05  ? 179 TYR C CD2 1 
ATOM   8068 C  CE1 . TYR D 2 183 ? -58.029 -2.614  41.319  1   81.33  ? 179 TYR C CE1 1 
ATOM   8069 C  CE2 . TYR D 2 183 ? -60.276 -2.475  40.518  1   85.84  ? 179 TYR C CE2 1 
ATOM   8070 C  CZ  . TYR D 2 183 ? -59.27  -3.203  41.133  1   87.24  ? 179 TYR C CZ  1 
ATOM   8071 O  OH  . TYR D 2 183 ? -59.555 -4.486  41.535  1   90.42  ? 179 TYR C OH  1 
ATOM   8072 N  N   . TYR D 2 184 ? -56.62  3.409   39.196  1   67.69  ? 180 TYR C N   1 
ATOM   8073 C  CA  . TYR D 2 184 ? -56.515 4.513   38.253  1   65.35  ? 180 TYR C CA  1 
ATOM   8074 C  C   . TYR D 2 184 ? -55.825 4.024   36.979  1   64.75  ? 180 TYR C C   1 
ATOM   8075 O  O   . TYR D 2 184 ? -55.2   2.966   36.974  1   67.94  ? 180 TYR C O   1 
ATOM   8076 C  CB  . TYR D 2 184 ? -55.793 5.716   38.862  1   63.64  ? 180 TYR C CB  1 
ATOM   8077 C  CG  . TYR D 2 184 ? -54.333 5.464   39.196  1   62     ? 180 TYR C CG  1 
ATOM   8078 C  CD1 . TYR D 2 184 ? -53.363 5.433   38.201  1   58.94  ? 180 TYR C CD1 1 
ATOM   8079 C  CD2 . TYR D 2 184 ? -53.93  5.241   40.51   1   63.46  ? 180 TYR C CD2 1 
ATOM   8080 C  CE1 . TYR D 2 184 ? -52.035 5.194   38.515  1   60.07  ? 180 TYR C CE1 1 
ATOM   8081 C  CE2 . TYR D 2 184 ? -52.603 5.003   40.836  1   61.56  ? 180 TYR C CE2 1 
ATOM   8082 C  CZ  . TYR D 2 184 ? -51.652 4.986   39.833  1   61.26  ? 180 TYR C CZ  1 
ATOM   8083 O  OH  . TYR D 2 184 ? -50.341 4.765   40.163  1   63.76  ? 180 TYR C OH  1 
ATOM   8084 N  N   . SER D 2 185 ? -55.906 4.837   35.918  1   63.14  ? 181 SER C N   1 
ATOM   8085 C  CA  . SER D 2 185 ? -55.65  4.402   34.554  1   60.77  ? 181 SER C CA  1 
ATOM   8086 C  C   . SER D 2 185 ? -55.199 5.597   33.717  1   58.98  ? 181 SER C C   1 
ATOM   8087 O  O   . SER D 2 185 ? -54.779 6.608   34.261  1   60.46  ? 181 SER C O   1 
ATOM   8088 C  CB  . SER D 2 185 ? -56.89  3.74    33.978  1   62.37  ? 181 SER C CB  1 
ATOM   8089 O  OG  . SER D 2 185 ? -56.636 3.157   32.707  1   61.28  ? 181 SER C OG  1 
ATOM   8090 N  N   . THR D 2 186 ? -55.298 5.476   32.393  1   59.2   ? 182 THR C N   1 
ATOM   8091 C  CA  . THR D 2 186 ? -54.734 6.426   31.445  1   58.83  ? 182 THR C CA  1 
ATOM   8092 C  C   . THR D 2 186 ? -55.353 7.811   31.624  1   60.05  ? 182 THR C C   1 
ATOM   8093 O  O   . THR D 2 186 ? -54.803 8.802   31.139  1   59.59  ? 182 THR C O   1 
ATOM   8094 C  CB  . THR D 2 186 ? -54.898 5.915   30.01   1   60.99  ? 182 THR C CB  1 
ATOM   8095 O  OG1 . THR D 2 186 ? -56.291 5.639   29.861  1   68.65  ? 182 THR C OG1 1 
ATOM   8096 C  CG2 . THR D 2 186 ? -54.073 4.674   29.703  1   57.55  ? 182 THR C CG2 1 
ATOM   8097 N  N   . ALA D 2 187 ? -56.459 7.898   32.372  1   62.53  ? 183 ALA C N   1 
ATOM   8098 C  CA  . ALA D 2 187 ? -57.143 9.176   32.555  1   65.06  ? 183 ALA C CA  1 
ATOM   8099 C  C   . ALA D 2 187 ? -56.289 10.206  33.309  1   65.49  ? 183 ALA C C   1 
ATOM   8100 O  O   . ALA D 2 187 ? -56.408 11.404  33.066  1   66.52  ? 183 ALA C O   1 
ATOM   8101 C  CB  . ALA D 2 187 ? -58.462 8.948   33.233  1   64.37  ? 183 ALA C CB  1 
ATOM   8102 N  N   . VAL D 2 188 ? -55.415 9.737   34.212  1   63.82  ? 184 VAL C N   1 
ATOM   8103 C  CA  . VAL D 2 188 ? -54.678 10.618  35.097  1   61.7   ? 184 VAL C CA  1 
ATOM   8104 C  C   . VAL D 2 188 ? -53.656 11.403  34.28   1   61.86  ? 184 VAL C C   1 
ATOM   8105 O  O   . VAL D 2 188 ? -53.344 12.546  34.603  1   67.24  ? 184 VAL C O   1 
ATOM   8106 C  CB  . VAL D 2 188 ? -53.994 9.825   36.223  1   60.73  ? 184 VAL C CB  1 
ATOM   8107 C  CG1 . VAL D 2 188 ? -54.966 8.849   36.876  1   61.78  ? 184 VAL C CG1 1 
ATOM   8108 C  CG2 . VAL D 2 188 ? -52.752 9.099   35.725  1   57.68  ? 184 VAL C CG2 1 
ATOM   8109 N  N   . ASP D 2 189 ? -53.143 10.803  33.211  1   56.23  ? 185 ASP C N   1 
ATOM   8110 C  CA  . ASP D 2 189 ? -52.197 11.53   32.393  1   55.99  ? 185 ASP C CA  1 
ATOM   8111 C  C   . ASP D 2 189 ? -52.9   12.659  31.648  1   56.14  ? 185 ASP C C   1 
ATOM   8112 O  O   . ASP D 2 189 ? -52.313 13.722  31.434  1   56.52  ? 185 ASP C O   1 
ATOM   8113 C  CB  . ASP D 2 189 ? -51.474 10.596  31.443  1   58.02  ? 185 ASP C CB  1 
ATOM   8114 C  CG  . ASP D 2 189 ? -50.363 9.76    32.067  1   59.44  ? 185 ASP C CG  1 
ATOM   8115 O  OD1 . ASP D 2 189 ? -49.866 10.111  33.18   1   53.34  ? 185 ASP C OD1 1 
ATOM   8116 O  OD2 . ASP D 2 189 ? -50.014 8.744   31.423  1   62.88  ? 185 ASP C OD2 1 
ATOM   8117 N  N   . ILE D 2 190 ? -54.155 12.415  31.247  1   56.23  ? 186 ILE C N   1 
ATOM   8118 C  CA  . ILE D 2 190 ? -54.918 13.406  30.506  1   57.55  ? 186 ILE C CA  1 
ATOM   8119 C  C   . ILE D 2 190 ? -55.215 14.6    31.406  1   58.19  ? 186 ILE C C   1 
ATOM   8120 O  O   . ILE D 2 190 ? -55.149 15.753  30.981  1   57.93  ? 186 ILE C O   1 
ATOM   8121 C  CB  . ILE D 2 190 ? -56.221 12.799  29.957  1   61.76  ? 186 ILE C CB  1 
ATOM   8122 C  CG1 . ILE D 2 190 ? -55.959 11.818  28.808  1   60.63  ? 186 ILE C CG1 1 
ATOM   8123 C  CG2 . ILE D 2 190 ? -57.202 13.897  29.533  1   62.25  ? 186 ILE C CG2 1 
ATOM   8124 C  CD1 . ILE D 2 190 ? -55.457 12.46   27.523  1   60.6   ? 186 ILE C CD1 1 
ATOM   8125 N  N   . TRP D 2 191 ? -55.566 14.308  32.655  1   57.79  ? 187 TRP C N   1 
ATOM   8126 C  CA  . TRP D 2 191 ? -55.842 15.366  33.604  1   58.48  ? 187 TRP C CA  1 
ATOM   8127 C  C   . TRP D 2 191 ? -54.638 16.308  33.644  1   56.29  ? 187 TRP C C   1 
ATOM   8128 O  O   . TRP D 2 191 ? -54.74  17.528  33.49   1   56.27  ? 187 TRP C O   1 
ATOM   8129 C  CB  . TRP D 2 191 ? -56.135 14.741  34.973  1   58.38  ? 187 TRP C CB  1 
ATOM   8130 C  CG  . TRP D 2 191 ? -56.438 15.767  36.027  1   59.14  ? 187 TRP C CG  1 
ATOM   8131 C  CD1 . TRP D 2 191 ? -55.536 16.344  36.859  1   57.33  ? 187 TRP C CD1 1 
ATOM   8132 C  CD2 . TRP D 2 191 ? -57.711 16.37   36.33   1   62.34  ? 187 TRP C CD2 1 
ATOM   8133 N  NE1 . TRP D 2 191 ? -56.151 17.234  37.688  1   58.43  ? 187 TRP C NE1 1 
ATOM   8134 C  CE2 . TRP D 2 191 ? -57.481 17.284  37.377  1   61.18  ? 187 TRP C CE2 1 
ATOM   8135 C  CE3 . TRP D 2 191 ? -59.011 16.223  35.832  1   64.71  ? 187 TRP C CE3 1 
ATOM   8136 C  CZ2 . TRP D 2 191 ? -58.502 18.048  37.928  1   62.3   ? 187 TRP C CZ2 1 
ATOM   8137 C  CZ3 . TRP D 2 191 ? -60.018 16.978  36.381  1   64.71  ? 187 TRP C CZ3 1 
ATOM   8138 C  CH2 . TRP D 2 191 ? -59.76  17.884  37.404  1   64.46  ? 187 TRP C CH2 1 
ATOM   8139 N  N   . SER D 2 192 ? -53.474 15.691  33.791  1   54.25  ? 188 SER C N   1 
ATOM   8140 C  CA  . SER D 2 192 ? -52.235 16.427  33.926  1   52.86  ? 188 SER C CA  1 
ATOM   8141 C  C   . SER D 2 192 ? -52.041 17.328  32.707  1   52.54  ? 188 SER C C   1 
ATOM   8142 O  O   . SER D 2 192 ? -51.817 18.529  32.846  1   51.5   ? 188 SER C O   1 
ATOM   8143 C  CB  . SER D 2 192 ? -51.087 15.462  34.163  1   53.4   ? 188 SER C CB  1 
ATOM   8144 O  OG  . SER D 2 192 ? -51.264 14.719  35.371  1   53.77  ? 188 SER C OG  1 
ATOM   8145 N  N   . LEU D 2 193 ? -52.192 16.756  31.506  1   52.46  ? 189 LEU C N   1 
ATOM   8146 C  CA  . LEU D 2 193 ? -52.104 17.534  30.282  1   53.2   ? 189 LEU C CA  1 
ATOM   8147 C  C   . LEU D 2 193 ? -53.157 18.646  30.257  1   56.82  ? 189 LEU C C   1 
ATOM   8148 O  O   . LEU D 2 193 ? -52.914 19.708  29.679  1   58.94  ? 189 LEU C O   1 
ATOM   8149 C  CB  . LEU D 2 193 ? -52.244 16.637  29.058  1   54.76  ? 189 LEU C CB  1 
ATOM   8150 C  CG  . LEU D 2 193 ? -51.021 15.796  28.693  1   57.15  ? 189 LEU C CG  1 
ATOM   8151 C  CD1 . LEU D 2 193 ? -51.179 15.243  27.274  1   57.49  ? 189 LEU C CD1 1 
ATOM   8152 C  CD2 . LEU D 2 193 ? -49.764 16.631  28.811  1   55.25  ? 189 LEU C CD2 1 
ATOM   8153 N  N   . GLY D 2 194 ? -54.338 18.409  30.846  1   54.65  ? 190 GLY C N   1 
ATOM   8154 C  CA  . GLY D 2 194 ? -55.351 19.444  30.841  1   56.5   ? 190 GLY C CA  1 
ATOM   8155 C  C   . GLY D 2 194 ? -54.924 20.622  31.709  1   57.27  ? 190 GLY C C   1 
ATOM   8156 O  O   . GLY D 2 194 ? -54.996 21.786  31.303  1   59.61  ? 190 GLY C O   1 
ATOM   8157 N  N   . CYS D 2 195 ? -54.455 20.286  32.907  1   56.61  ? 191 CYS C N   1 
ATOM   8158 C  CA  . CYS D 2 195 ? -53.779 21.244  33.762  1   57.28  ? 191 CYS C CA  1 
ATOM   8159 C  C   . CYS D 2 195 ? -52.673 21.984  33.008  1   57.02  ? 191 CYS C C   1 
ATOM   8160 O  O   . CYS D 2 195 ? -52.495 23.185  33.23   1   58.97  ? 191 CYS C O   1 
ATOM   8161 C  CB  . CYS D 2 195 ? -53.211 20.565  34.997  1   55.33  ? 191 CYS C CB  1 
ATOM   8162 S  SG  . CYS D 2 195 ? -54.475 19.761  36.016  1   61.58  ? 191 CYS C SG  1 
ATOM   8163 N  N   . ILE D 2 196 ? -51.944 21.279  32.124  1   53.98  ? 192 ILE C N   1 
ATOM   8164 C  CA  . ILE D 2 196 ? -50.827 21.872  31.398  1   52.38  ? 192 ILE C CA  1 
ATOM   8165 C  C   . ILE D 2 196 ? -51.318 22.786  30.27   1   51.86  ? 192 ILE C C   1 
ATOM   8166 O  O   . ILE D 2 196 ? -50.786 23.882  30.104  1   53.37  ? 192 ILE C O   1 
ATOM   8167 C  CB  . ILE D 2 196 ? -49.782 20.812  30.972  1   51.89  ? 192 ILE C CB  1 
ATOM   8168 C  CG1 . ILE D 2 196 ? -49.003 20.302  32.215  1   51.65  ? 192 ILE C CG1 1 
ATOM   8169 C  CG2 . ILE D 2 196 ? -48.816 21.357  29.905  1   48.04  ? 192 ILE C CG2 1 
ATOM   8170 C  CD1 . ILE D 2 196 ? -48.58  18.84   32.171  1   50.25  ? 192 ILE C CD1 1 
ATOM   8171 N  N   . PHE D 2 197 ? -52.335 22.358  29.506  1   51.86  ? 193 PHE C N   1 
ATOM   8172 C  CA  . PHE D 2 197 ? -52.995 23.229  28.539  1   52.69  ? 193 PHE C CA  1 
ATOM   8173 C  C   . PHE D 2 197 ? -53.295 24.581  29.189  1   53.33  ? 193 PHE C C   1 
ATOM   8174 O  O   . PHE D 2 197 ? -52.796 25.618  28.753  1   52.92  ? 193 PHE C O   1 
ATOM   8175 C  CB  . PHE D 2 197 ? -54.273 22.546  28.034  1   54.7   ? 193 PHE C CB  1 
ATOM   8176 C  CG  . PHE D 2 197 ? -55.05  23.239  26.924  1   55.03  ? 193 PHE C CG  1 
ATOM   8177 C  CD1 . PHE D 2 197 ? -54.473 24.243  26.147  1   55.29  ? 193 PHE C CD1 1 
ATOM   8178 C  CD2 . PHE D 2 197 ? -56.356 22.857  26.642  1   56.67  ? 193 PHE C CD2 1 
ATOM   8179 C  CE1 . PHE D 2 197 ? -55.196 24.848  25.118  1   58.04  ? 193 PHE C CE1 1 
ATOM   8180 C  CE2 . PHE D 2 197 ? -57.076 23.475  25.619  1   59.34  ? 193 PHE C CE2 1 
ATOM   8181 C  CZ  . PHE D 2 197 ? -56.501 24.471  24.854  1   59.28  ? 193 PHE C CZ  1 
ATOM   8182 N  N   . ALA D 2 198 ? -54.091 24.547  30.259  1   54.05  ? 194 ALA C N   1 
ATOM   8183 C  CA  . ALA D 2 198 ? -54.488 25.749  30.97   1   57.55  ? 194 ALA C CA  1 
ATOM   8184 C  C   . ALA D 2 198 ? -53.291 26.65   31.288  1   60.03  ? 194 ALA C C   1 
ATOM   8185 O  O   . ALA D 2 198 ? -53.39  27.878  31.18   1   64.05  ? 194 ALA C O   1 
ATOM   8186 C  CB  . ALA D 2 198 ? -55.239 25.36   32.216  1   56.12  ? 194 ALA C CB  1 
ATOM   8187 N  N   . GLU D 2 199 ? -52.175 26.033  31.699  1   59.73  ? 195 GLU C N   1 
ATOM   8188 C  CA  . GLU D 2 199 ? -51.008 26.747  32.204  1   61.92  ? 195 GLU C CA  1 
ATOM   8189 C  C   . GLU D 2 199 ? -50.3   27.463  31.051  1   61.79  ? 195 GLU C C   1 
ATOM   8190 O  O   . GLU D 2 199 ? -49.881 28.605  31.205  1   63.84  ? 195 GLU C O   1 
ATOM   8191 C  CB  . GLU D 2 199 ? -50.124 25.801  33.026  1   60.63  ? 195 GLU C CB  1 
ATOM   8192 C  CG  . GLU D 2 199 ? -49.044 26.472  33.876  1   60.15  ? 195 GLU C CG  1 
ATOM   8193 C  CD  . GLU D 2 199 ? -48.262 25.542  34.803  1   60.05  ? 195 GLU C CD  1 
ATOM   8194 O  OE1 . GLU D 2 199 ? -48.697 24.388  35.029  1   58.32  ? 195 GLU C OE1 1 
ATOM   8195 O  OE2 . GLU D 2 199 ? -47.196 25.98   35.307  1   61.55  ? 195 GLU C OE2 1 
ATOM   8196 N  N   . MET D 2 200 ? -50.209 26.813  29.886  1   59.89  ? 196 MET C N   1 
ATOM   8197 C  CA  . MET D 2 200 ? -49.603 27.444  28.721  1   61.89  ? 196 MET C CA  1 
ATOM   8198 C  C   . MET D 2 200 ? -50.368 28.714  28.333  1   66.01  ? 196 MET C C   1 
ATOM   8199 O  O   . MET D 2 200 ? -49.785 29.725  27.947  1   74.13  ? 196 MET C O   1 
ATOM   8200 C  CB  . MET D 2 200 ? -49.565 26.472  27.541  1   58.49  ? 196 MET C CB  1 
ATOM   8201 C  CG  . MET D 2 200 ? -48.59  25.338  27.706  1   53.72  ? 196 MET C CG  1 
ATOM   8202 S  SD  . MET D 2 200 ? -48.425 24.387  26.181  1   57.09  ? 196 MET C SD  1 
ATOM   8203 C  CE  . MET D 2 200 ? -49.853 23.299  26.123  1   52.76  ? 196 MET C CE  1 
ATOM   8204 N  N   . VAL D 2 201 ? -51.69  28.681  28.482  1   66.73  ? 197 VAL C N   1 
ATOM   8205 C  CA  . VAL D 2 201 ? -52.552 29.8    28.129  1   68.19  ? 197 VAL C CA  1 
ATOM   8206 C  C   . VAL D 2 201 ? -52.395 30.973  29.109  1   68.56  ? 197 VAL C C   1 
ATOM   8207 O  O   . VAL D 2 201 ? -52.34  32.119  28.673  1   68.15  ? 197 VAL C O   1 
ATOM   8208 C  CB  . VAL D 2 201 ? -54.004 29.284  28.068  1   68.07  ? 197 VAL C CB  1 
ATOM   8209 C  CG1 . VAL D 2 201 ? -55.016 30.416  27.992  1   70.93  ? 197 VAL C CG1 1 
ATOM   8210 C  CG2 . VAL D 2 201 ? -54.211 28.295  26.925  1   64.27  ? 197 VAL C CG2 1 
ATOM   8211 N  N   . THR D 2 202 ? -52.332 30.696  30.426  1   67.08  ? 198 THR C N   1 
ATOM   8212 C  CA  . THR D 2 202 ? -52.298 31.731  31.462  1   65.77  ? 198 THR C CA  1 
ATOM   8213 C  C   . THR D 2 202 ? -50.892 31.927  32.036  1   65.54  ? 198 THR C C   1 
ATOM   8214 O  O   . THR D 2 202 ? -50.644 32.949  32.675  1   64.04  ? 198 THR C O   1 
ATOM   8215 C  CB  . THR D 2 202 ? -53.268 31.429  32.608  1   65.23  ? 198 THR C CB  1 
ATOM   8216 O  OG1 . THR D 2 202 ? -52.813 30.245  33.272  1   66.75  ? 198 THR C OG1 1 
ATOM   8217 C  CG2 . THR D 2 202 ? -54.704 31.263  32.144  1   64.6   ? 198 THR C CG2 1 
ATOM   8218 N  N   . ARG D 2 203 ? -50.01  30.918  31.903  1   64.91  ? 199 ARG C N   1 
ATOM   8219 C  CA  . ARG D 2 203 ? -48.65  30.954  32.442  1   65.57  ? 199 ARG C CA  1 
ATOM   8220 C  C   . ARG D 2 203 ? -48.613 30.96   33.972  1   66.3   ? 199 ARG C C   1 
ATOM   8221 O  O   . ARG D 2 203 ? -47.544 31.133  34.547  1   68.45  ? 199 ARG C O   1 
ATOM   8222 C  CB  . ARG D 2 203 ? -47.832 32.122  31.874  1   67.21  ? 199 ARG C CB  1 
ATOM   8223 C  CG  . ARG D 2 203 ? -47.385 31.891  30.439  1   66.41  ? 199 ARG C CG  1 
ATOM   8224 C  CD  . ARG D 2 203 ? -47.499 33.163  29.614  1   71.41  ? 199 ARG C CD  1 
ATOM   8225 N  NE  . ARG D 2 203 ? -48.868 33.681  29.466  1   73.08  ? 199 ARG C NE  1 
ATOM   8226 C  CZ  . ARG D 2 203 ? -49.22  34.945  29.668  1   75.35  ? 199 ARG C CZ  1 
ATOM   8227 N  NH1 . ARG D 2 203 ? -48.302 35.854  29.957  1   76.03  ? 199 ARG C NH1 1 
ATOM   8228 N  NH2 . ARG D 2 203 ? -50.497 35.291  29.589  1   79.18  ? 199 ARG C NH2 1 
ATOM   8229 N  N   . ARG D 2 204 ? -49.773 30.794  34.621  1   66.34  ? 200 ARG C N   1 
ATOM   8230 C  CA  . ARG D 2 204 ? -49.862 30.367  36.007  1   63.14  ? 200 ARG C CA  1 
ATOM   8231 C  C   . ARG D 2 204 ? -50.471 28.97   35.982  1   61.48  ? 200 ARG C C   1 
ATOM   8232 O  O   . ARG D 2 204 ? -51.241 28.68   35.073  1   65.27  ? 200 ARG C O   1 
ATOM   8233 C  CB  . ARG D 2 204 ? -50.811 31.291  36.771  1   67.48  ? 200 ARG C CB  1 
ATOM   8234 C  CG  . ARG D 2 204 ? -50.657 32.768  36.445  1   74.39  ? 200 ARG C CG  1 
ATOM   8235 C  CD  . ARG D 2 204 ? -51.348 33.629  37.502  1   83.59  ? 200 ARG C CD  1 
ATOM   8236 N  NE  . ARG D 2 204 ? -51.399 35.059  37.163  1   91.58  ? 200 ARG C NE  1 
ATOM   8237 C  CZ  . ARG D 2 204 ? -52.02  35.632  36.118  1   96.26  ? 200 ARG C CZ  1 
ATOM   8238 N  NH1 . ARG D 2 204 ? -52.684 34.902  35.239  1   96.79  ? 200 ARG C NH1 1 
ATOM   8239 N  NH2 . ARG D 2 204 ? -51.991 36.946  35.953  1   99.36  ? 200 ARG C NH2 1 
ATOM   8240 N  N   . ALA D 2 205 ? -50.099 28.111  36.946  1   58.09  ? 201 ALA C N   1 
ATOM   8241 C  CA  . ALA D 2 205 ? -50.693 26.797  37.171  1   53.95  ? 201 ALA C CA  1 
ATOM   8242 C  C   . ALA D 2 205 ? -52.173 26.954  37.486  1   55.99  ? 201 ALA C C   1 
ATOM   8243 O  O   . ALA D 2 205 ? -52.568 27.972  38.05   1   60.23  ? 201 ALA C O   1 
ATOM   8244 C  CB  . ALA D 2 205 ? -49.987 26.119  38.317  1   51.94  ? 201 ALA C CB  1 
ATOM   8245 N  N   . LEU D 2 206 ? -52.969 25.934  37.141  1   56.47  ? 202 LEU C N   1 
ATOM   8246 C  CA  . LEU D 2 206 ? -54.42  25.963  37.27   1   57.84  ? 202 LEU C CA  1 
ATOM   8247 C  C   . LEU D 2 206 ? -54.868 25.632  38.699  1   60.46  ? 202 LEU C C   1 
ATOM   8248 O  O   . LEU D 2 206 ? -55.732 26.309  39.235  1   63.23  ? 202 LEU C O   1 
ATOM   8249 C  CB  . LEU D 2 206 ? -55.009 24.992  36.253  1   55.7   ? 202 LEU C CB  1 
ATOM   8250 C  CG  . LEU D 2 206 ? -56.533 24.968  36.118  1   58.13  ? 202 LEU C CG  1 
ATOM   8251 C  CD1 . LEU D 2 206 ? -57.051 26.316  35.579  1   58.68  ? 202 LEU C CD1 1 
ATOM   8252 C  CD2 . LEU D 2 206 ? -56.93  23.784  35.214  1   56.13  ? 202 LEU C CD2 1 
ATOM   8253 N  N   . PHE D 2 207 ? -54.285 24.6    39.325  1   61.68  ? 203 PHE C N   1 
ATOM   8254 C  CA  . PHE D 2 207 ? -54.695 24.186  40.662  1   63.65  ? 203 PHE C CA  1 
ATOM   8255 C  C   . PHE D 2 207 ? -53.485 24.154  41.6    1   64.28  ? 203 PHE C C   1 
ATOM   8256 O  O   . PHE D 2 207 ? -52.982 23.08   41.933  1   65.98  ? 203 PHE C O   1 
ATOM   8257 C  CB  . PHE D 2 207 ? -55.449 22.85   40.574  1   59.91  ? 203 PHE C CB  1 
ATOM   8258 C  CG  . PHE D 2 207 ? -56.68  22.881  39.678  1   59.92  ? 203 PHE C CG  1 
ATOM   8259 C  CD1 . PHE D 2 207 ? -57.687 23.818  39.868  1   60.22  ? 203 PHE C CD1 1 
ATOM   8260 C  CD2 . PHE D 2 207 ? -56.805 21.992  38.613  1   59.8   ? 203 PHE C CD2 1 
ATOM   8261 C  CE1 . PHE D 2 207 ? -58.794 23.844  39.028  1   61.7   ? 203 PHE C CE1 1 
ATOM   8262 C  CE2 . PHE D 2 207 ? -57.913 22.021  37.776  1   59.84  ? 203 PHE C CE2 1 
ATOM   8263 C  CZ  . PHE D 2 207 ? -58.913 22.941  37.993  1   61.44  ? 203 PHE C CZ  1 
ATOM   8264 N  N   . PRO D 2 208 ? -52.98  25.321  42.072  1   64.51  ? 204 PRO C N   1 
ATOM   8265 C  CA  . PRO D 2 208 ? -51.769 25.349  42.903  1   64.96  ? 204 PRO C CA  1 
ATOM   8266 C  C   . PRO D 2 208 ? -52.044 25.161  44.397  1   65.56  ? 204 PRO C C   1 
ATOM   8267 O  O   . PRO D 2 208 ? -52.097 26.133  45.148  1   69.05  ? 204 PRO C O   1 
ATOM   8268 C  CB  . PRO D 2 208 ? -51.237 26.768  42.572  1   62.87  ? 204 PRO C CB  1 
ATOM   8269 C  CG  . PRO D 2 208 ? -52.504 27.612  42.489  1   63.29  ? 204 PRO C CG  1 
ATOM   8270 C  CD  . PRO D 2 208 ? -53.52  26.67   41.823  1   64.24  ? 204 PRO C CD  1 
ATOM   8271 N  N   . GLY D 2 209 ? -52.211 23.908  44.823  1   62.94  ? 205 GLY C N   1 
ATOM   8272 C  CA  . GLY D 2 209 ? -52.621 23.653  46.192  1   67     ? 205 GLY C CA  1 
ATOM   8273 C  C   . GLY D 2 209 ? -51.438 23.519  47.147  1   68.45  ? 205 GLY C C   1 
ATOM   8274 O  O   . GLY D 2 209 ? -50.355 23.135  46.709  1   69.66  ? 205 GLY C O   1 
ATOM   8275 N  N   . ASP D 2 210 ? -51.688 23.784  48.443  1   69.17  ? 206 ASP C N   1 
ATOM   8276 C  CA  . ASP D 2 210 ? -50.703 23.693  49.509  1   70.91  ? 206 ASP C CA  1 
ATOM   8277 C  C   . ASP D 2 210 ? -50.79  22.353  50.23   1   73.45  ? 206 ASP C C   1 
ATOM   8278 O  O   . ASP D 2 210 ? -49.907 21.996  51.006  1   75.13  ? 206 ASP C O   1 
ATOM   8279 C  CB  . ASP D 2 210 ? -50.933 24.771  50.549  1   74.36  ? 206 ASP C CB  1 
ATOM   8280 C  CG  . ASP D 2 210 ? -51.039 26.168  49.96   1   75.67  ? 206 ASP C CG  1 
ATOM   8281 O  OD1 . ASP D 2 210 ? -50.239 26.451  49.03   1   73.17  ? 206 ASP C OD1 1 
ATOM   8282 O  OD2 . ASP D 2 210 ? -51.913 26.943  50.43   1   75.53  ? 206 ASP C OD2 1 
ATOM   8283 N  N   . SER D 2 211 ? -51.879 21.627  49.985  1   75.83  ? 207 SER C N   1 
ATOM   8284 C  CA  . SER D 2 211 ? -52.179 20.383  50.676  1   74.88  ? 207 SER C CA  1 
ATOM   8285 C  C   . SER D 2 211 ? -53.159 19.59   49.821  1   75.06  ? 207 SER C C   1 
ATOM   8286 O  O   . SER D 2 211 ? -53.735 20.15   48.893  1   78.25  ? 207 SER C O   1 
ATOM   8287 C  CB  . SER D 2 211 ? -52.731 20.667  52.056  1   75.28  ? 207 SER C CB  1 
ATOM   8288 O  OG  . SER D 2 211 ? -53.771 21.637  52.025  1   73.63  ? 207 SER C OG  1 
ATOM   8289 N  N   . GLU D 2 212 ? -53.359 18.307  50.136  1   75.28  ? 208 GLU C N   1 
ATOM   8290 C  CA  . GLU D 2 212 ? -54.334 17.505  49.411  1   76.53  ? 208 GLU C CA  1 
ATOM   8291 C  C   . GLU D 2 212 ? -55.726 18.131  49.526  1   79.48  ? 208 GLU C C   1 
ATOM   8292 O  O   . GLU D 2 212 ? -56.467 18.204  48.538  1   78.85  ? 208 GLU C O   1 
ATOM   8293 C  CB  . GLU D 2 212 ? -54.324 16.068  49.929  1   80.17  ? 208 GLU C CB  1 
ATOM   8294 C  CG  . GLU D 2 212 ? -53.106 15.259  49.488  1   81.48  ? 208 GLU C CG  1 
ATOM   8295 C  CD  . GLU D 2 212 ? -52.773 14.052  50.353  1   83.92  ? 208 GLU C CD  1 
ATOM   8296 O  OE1 . GLU D 2 212 ? -53.45  13.83   51.383  1   87.18  ? 208 GLU C OE1 1 
ATOM   8297 O  OE2 . GLU D 2 212 ? -51.809 13.345  50.01   1   81.41  ? 208 GLU C OE2 1 
ATOM   8298 N  N   . ILE D 2 213 ? -56.075 18.586  50.741  1   80.9   ? 209 ILE C N   1 
ATOM   8299 C  CA  . ILE D 2 213 ? -57.392 19.159  50.978  1   82.69  ? 209 ILE C CA  1 
ATOM   8300 C  C   . ILE D 2 213 ? -57.557 20.453  50.168  1   79.91  ? 209 ILE C C   1 
ATOM   8301 O  O   . ILE D 2 213 ? -58.644 20.744  49.678  1   80.06  ? 209 ILE C O   1 
ATOM   8302 C  CB  . ILE D 2 213 ? -57.675 19.328  52.486  1   86.06  ? 209 ILE C CB  1 
ATOM   8303 C  CG1 . ILE D 2 213 ? -59.121 19.699  52.76   1   90.9   ? 209 ILE C CG1 1 
ATOM   8304 C  CG2 . ILE D 2 213 ? -56.707 20.296  53.162  1   89.46  ? 209 ILE C CG2 1 
ATOM   8305 C  CD1 . ILE D 2 213 ? -60.049 18.497  52.776  1   100.7  ? 209 ILE C CD1 1 
ATOM   8306 N  N   . ASP D 2 214 ? -56.469 21.224  50.011  1   74.68  ? 210 ASP C N   1 
ATOM   8307 C  CA  . ASP D 2 214 ? -56.531 22.526  49.38   1   70.54  ? 210 ASP C CA  1 
ATOM   8308 C  C   . ASP D 2 214 ? -56.686 22.322  47.887  1   67.12  ? 210 ASP C C   1 
ATOM   8309 O  O   . ASP D 2 214 ? -57.412 23.07   47.23   1   65.12  ? 210 ASP C O   1 
ATOM   8310 C  CB  . ASP D 2 214 ? -55.257 23.311  49.611  1   70.19  ? 210 ASP C CB  1 
ATOM   8311 C  CG  . ASP D 2 214 ? -55.311 24.755  49.144  1   69.85  ? 210 ASP C CG  1 
ATOM   8312 O  OD1 . ASP D 2 214 ? -56.303 25.435  49.514  1   71.08  ? 210 ASP C OD1 1 
ATOM   8313 O  OD2 . ASP D 2 214 ? -54.351 25.179  48.445  1   66.19  ? 210 ASP C OD2 1 
ATOM   8314 N  N   . GLN D 2 215 ? -55.966 21.304  47.397  1   65.51  ? 211 GLN C N   1 
ATOM   8315 C  CA  . GLN D 2 215 ? -56.029 20.856  46.016  1   64.37  ? 211 GLN C CA  1 
ATOM   8316 C  C   . GLN D 2 215 ? -57.46  20.475  45.638  1   66.28  ? 211 GLN C C   1 
ATOM   8317 O  O   . GLN D 2 215 ? -57.956 20.902  44.599  1   66.32  ? 211 GLN C O   1 
ATOM   8318 C  CB  . GLN D 2 215 ? -55.142 19.636  45.82   1   63.77  ? 211 GLN C CB  1 
ATOM   8319 C  CG  . GLN D 2 215 ? -54.886 19.315  44.353  1   63.89  ? 211 GLN C CG  1 
ATOM   8320 C  CD  . GLN D 2 215 ? -53.953 20.296  43.68   1   64.08  ? 211 GLN C CD  1 
ATOM   8321 O  OE1 . GLN D 2 215 ? -53.231 21.061  44.331  1   64.25  ? 211 GLN C OE1 1 
ATOM   8322 N  NE2 . GLN D 2 215 ? -53.95  20.262  42.358  1   63.63  ? 211 GLN C NE2 1 
ATOM   8323 N  N   . LEU D 2 216 ? -58.117 19.68   46.494  1   68.03  ? 212 LEU C N   1 
ATOM   8324 C  CA  . LEU D 2 216 ? -59.488 19.264  46.248  1   70.15  ? 212 LEU C CA  1 
ATOM   8325 C  C   . LEU D 2 216 ? -60.385 20.487  46.084  1   71.83  ? 212 LEU C C   1 
ATOM   8326 O  O   . LEU D 2 216 ? -61.065 20.637  45.063  1   72.35  ? 212 LEU C O   1 
ATOM   8327 C  CB  . LEU D 2 216 ? -59.97  18.334  47.355  1   73.65  ? 212 LEU C CB  1 
ATOM   8328 C  CG  . LEU D 2 216 ? -59.593 16.867  47.143  1   75.35  ? 212 LEU C CG  1 
ATOM   8329 C  CD1 . LEU D 2 216 ? -59.607 16.03   48.414  1   76.85  ? 212 LEU C CD1 1 
ATOM   8330 C  CD2 . LEU D 2 216 ? -60.542 16.289  46.097  1   76.67  ? 212 LEU C CD2 1 
ATOM   8331 N  N   . PHE D 2 217 ? -60.341 21.372  47.088  1   71.64  ? 213 PHE C N   1 
ATOM   8332 C  CA  . PHE D 2 217 ? -61.125 22.598  47.084  1   72.78  ? 213 PHE C CA  1 
ATOM   8333 C  C   . PHE D 2 217 ? -60.814 23.432  45.835  1   71.31  ? 213 PHE C C   1 
ATOM   8334 O  O   . PHE D 2 217 ? -61.71  24.035  45.271  1   71.46  ? 213 PHE C O   1 
ATOM   8335 C  CB  . PHE D 2 217 ? -60.93  23.367  48.4    1   73.94  ? 213 PHE C CB  1 
ATOM   8336 C  CG  . PHE D 2 217 ? -61.408 22.7    49.687  1   75.46  ? 213 PHE C CG  1 
ATOM   8337 C  CD1 . PHE D 2 217 ? -61.736 21.343  49.733  1   75.12  ? 213 PHE C CD1 1 
ATOM   8338 C  CD2 . PHE D 2 217 ? -61.51  23.436  50.86   1   76.56  ? 213 PHE C CD2 1 
ATOM   8339 C  CE1 . PHE D 2 217 ? -62.164 20.755  50.91   1   76.85  ? 213 PHE C CE1 1 
ATOM   8340 C  CE2 . PHE D 2 217 ? -61.955 22.847  52.037  1   79.47  ? 213 PHE C CE2 1 
ATOM   8341 C  CZ  . PHE D 2 217 ? -62.263 21.505  52.068  1   79.52  ? 213 PHE C CZ  1 
ATOM   8342 N  N   . ARG D 2 218 ? -59.554 23.442  45.379  1   69.57  ? 214 ARG C N   1 
ATOM   8343 C  CA  . ARG D 2 218 ? -59.161 24.292  44.265  1   69.05  ? 214 ARG C CA  1 
ATOM   8344 C  C   . ARG D 2 218 ? -59.841 23.865  42.963  1   69.51  ? 214 ARG C C   1 
ATOM   8345 O  O   . ARG D 2 218 ? -60.172 24.723  42.139  1   69.14  ? 214 ARG C O   1 
ATOM   8346 C  CB  . ARG D 2 218 ? -57.635 24.37   44.155  1   65.85  ? 214 ARG C CB  1 
ATOM   8347 C  CG  . ARG D 2 218 ? -57.07  25.38   45.143  1   66     ? 214 ARG C CG  1 
ATOM   8348 C  CD  . ARG D 2 218 ? -55.547 25.366  45.2    1   63.95  ? 214 ARG C CD  1 
ATOM   8349 N  NE  . ARG D 2 218 ? -55.047 26.488  46.002  1   65.98  ? 214 ARG C NE  1 
ATOM   8350 C  CZ  . ARG D 2 218 ? -55.099 27.752  45.614  1   67.11  ? 214 ARG C CZ  1 
ATOM   8351 N  NH1 . ARG D 2 218 ? -55.421 28.045  44.364  1   67.4   ? 214 ARG C NH1 1 
ATOM   8352 N  NH2 . ARG D 2 218 ? -54.807 28.705  46.48   1   67.8   ? 214 ARG C NH2 1 
ATOM   8353 N  N   . ILE D 2 219 ? -60.046 22.547  42.801  1   70.35  ? 215 ILE C N   1 
ATOM   8354 C  CA  . ILE D 2 219 ? -60.667 21.93   41.63   1   72.66  ? 215 ILE C CA  1 
ATOM   8355 C  C   . ILE D 2 219 ? -62.198 22.121  41.631  1   78.52  ? 215 ILE C C   1 
ATOM   8356 O  O   . ILE D 2 219 ? -62.779 22.613  40.642  1   75.54  ? 215 ILE C O   1 
ATOM   8357 C  CB  . ILE D 2 219 ? -60.235 20.45   41.552  1   69.78  ? 215 ILE C CB  1 
ATOM   8358 C  CG1 . ILE D 2 219 ? -58.72  20.331  41.288  1   65.24  ? 215 ILE C CG1 1 
ATOM   8359 C  CG2 . ILE D 2 219 ? -61.058 19.667  40.523  1   69.41  ? 215 ILE C CG2 1 
ATOM   8360 C  CD1 . ILE D 2 219 ? -58.094 19.018  41.72   1   63.3   ? 215 ILE C CD1 1 
ATOM   8361 N  N   . PHE D 2 220 ? -62.832 21.729  42.759  1   80.98  ? 216 PHE C N   1 
ATOM   8362 C  CA  . PHE D 2 220 ? -64.267 21.834  42.99   1   83.47  ? 216 PHE C CA  1 
ATOM   8363 C  C   . PHE D 2 220 ? -64.781 23.215  42.599  1   86.47  ? 216 PHE C C   1 
ATOM   8364 O  O   . PHE D 2 220 ? -65.635 23.34   41.726  1   91.86  ? 216 PHE C O   1 
ATOM   8365 C  CB  . PHE D 2 220 ? -64.621 21.537  44.446  1   83.38  ? 216 PHE C CB  1 
ATOM   8366 C  CG  . PHE D 2 220 ? -64.343 20.104  44.863  1   88.16  ? 216 PHE C CG  1 
ATOM   8367 C  CD1 . PHE D 2 220 ? -63.902 19.149  43.944  1   89.32  ? 216 PHE C CD1 1 
ATOM   8368 C  CD2 . PHE D 2 220 ? -64.54  19.701  46.181  1   92.53  ? 216 PHE C CD2 1 
ATOM   8369 C  CE1 . PHE D 2 220 ? -63.655 17.835  44.333  1   91.52  ? 216 PHE C CE1 1 
ATOM   8370 C  CE2 . PHE D 2 220 ? -64.289 18.386  46.571  1   95.44  ? 216 PHE C CE2 1 
ATOM   8371 C  CZ  . PHE D 2 220 ? -63.849 17.454  45.647  1   93.17  ? 216 PHE C CZ  1 
ATOM   8372 N  N   . ARG D 2 221 ? -64.203 24.238  43.217  1   86.84  ? 217 ARG C N   1 
ATOM   8373 C  CA  . ARG D 2 221 ? -64.651 25.628  42.975  1   90.26  ? 217 ARG C CA  1 
ATOM   8374 C  C   . ARG D 2 221 ? -64.446 26.047  41.519  1   92.84  ? 217 ARG C C   1 
ATOM   8375 O  O   . ARG D 2 221 ? -65.083 27.03   41.102  1   94.05  ? 217 ARG C O   1 
ATOM   8376 C  CB  . ARG D 2 221 ? -63.837 26.547  43.887  1   89.47  ? 217 ARG C CB  1 
ATOM   8377 C  CG  . ARG D 2 221 ? -62.376 26.787  43.544  1   87.6   ? 217 ARG C CG  1 
ATOM   8378 C  CD  . ARG D 2 221 ? -61.784 27.737  44.566  1   92.35  ? 217 ARG C CD  1 
ATOM   8379 N  NE  . ARG D 2 221 ? -60.323 27.649  44.621  1   95.66  ? 217 ARG C NE  1 
ATOM   8380 C  CZ  . ARG D 2 221 ? -59.505 28.464  43.974  1   92.46  ? 217 ARG C CZ  1 
ATOM   8381 N  NH1 . ARG D 2 221 ? -58.894 28.054  42.877  1   89.8   ? 217 ARG C NH1 1 
ATOM   8382 N  NH2 . ARG D 2 221 ? -59.303 29.686  44.43   1   93.96  ? 217 ARG C NH2 1 
ATOM   8383 N  N   . THR D 2 222 ? -63.58  25.361  40.778  1   94.92  ? 218 THR C N   1 
ATOM   8384 C  CA  . THR D 2 222 ? -63.301 25.832  39.409  1   94.82  ? 218 THR C CA  1 
ATOM   8385 C  C   . THR D 2 222 ? -64.164 25.066  38.443  1   98     ? 218 THR C C   1 
ATOM   8386 O  O   . THR D 2 222 ? -64.783 25.707  37.572  1   97.31  ? 218 THR C O   1 
ATOM   8387 C  CB  . THR D 2 222 ? -61.816 25.674  39.099  1   90.34  ? 218 THR C CB  1 
ATOM   8388 O  OG1 . THR D 2 222 ? -61.15  26.594  39.956  1   88.71  ? 218 THR C OG1 1 
ATOM   8389 C  CG2 . THR D 2 222 ? -61.483 25.993  37.653  1   86.43  ? 218 THR C CG2 1 
ATOM   8390 N  N   . LEU D 2 223 ? -64.238 23.749  38.604  1   98.57  ? 219 LEU C N   1 
ATOM   8391 C  CA  . LEU D 2 223 ? -64.976 22.928  37.613  1   101.24 ? 219 LEU C CA  1 
ATOM   8392 C  C   . LEU D 2 223 ? -66.395 22.64   38.115  1   105.91 ? 219 LEU C C   1 
ATOM   8393 O  O   . LEU D 2 223 ? -67.198 22.105  37.329  1   107.2  ? 219 LEU C O   1 
ATOM   8394 C  CB  . LEU D 2 223 ? -64.174 21.654  37.359  1   95.04  ? 219 LEU C CB  1 
ATOM   8395 C  CG  . LEU D 2 223 ? -62.682 21.852  37.085  1   89.55  ? 219 LEU C CG  1 
ATOM   8396 C  CD1 . LEU D 2 223 ? -62.004 20.504  37.011  1   89.44  ? 219 LEU C CD1 1 
ATOM   8397 C  CD2 . LEU D 2 223 ? -62.483 22.618  35.792  1   87.34  ? 219 LEU C CD2 1 
ATOM   8398 N  N   . GLY D 2 224 ? -66.687 22.991  39.365  1   108.41 ? 220 GLY C N   1 
ATOM   8399 C  CA  . GLY D 2 224 ? -68.051 22.81   39.89   1   111.73 ? 220 GLY C CA  1 
ATOM   8400 C  C   . GLY D 2 224 ? -68.11  21.654  40.859  1   112.42 ? 220 GLY C C   1 
ATOM   8401 O  O   . GLY D 2 224 ? -67.749 20.54   40.457  1   104.52 ? 220 GLY C O   1 
ATOM   8402 N  N   . THR D 2 225 ? -68.555 21.906  42.089  1   123.36 ? 221 THR C N   1 
ATOM   8403 C  CA  . THR D 2 225 ? -68.552 20.839  43.111  1   132.51 ? 221 THR C CA  1 
ATOM   8404 C  C   . THR D 2 225 ? -69.094 19.589  42.466  1   143    ? 221 THR C C   1 
ATOM   8405 O  O   . THR D 2 225 ? -70.278 19.595  42.065  1   153.46 ? 221 THR C O   1 
ATOM   8406 C  CB  . THR D 2 225 ? -69.356 21.261  44.337  1   128.13 ? 221 THR C CB  1 
ATOM   8407 O  OG1 . THR D 2 225 ? -68.705 22.439  44.798  1   124.97 ? 221 THR C OG1 1 
ATOM   8408 C  CG2 . THR D 2 225 ? -69.35  20.2    45.42   1   126.34 ? 221 THR C CG2 1 
ATOM   8409 N  N   . PRO D 2 226 ? -68.296 18.512  42.328  1   144.12 ? 222 PRO C N   1 
ATOM   8410 C  CA  . PRO D 2 226 ? -68.754 17.337  41.603  1   143.93 ? 222 PRO C CA  1 
ATOM   8411 C  C   . PRO D 2 226 ? -69.935 16.657  42.272  1   144.11 ? 222 PRO C C   1 
ATOM   8412 O  O   . PRO D 2 226 ? -69.958 16.524  43.511  1   139.05 ? 222 PRO C O   1 
ATOM   8413 C  CB  . PRO D 2 226 ? -67.502 16.445  41.55   1   138.69 ? 222 PRO C CB  1 
ATOM   8414 C  CG  . PRO D 2 226 ? -66.676 16.904  42.725  1   136.21 ? 222 PRO C CG  1 
ATOM   8415 C  CD  . PRO D 2 226 ? -66.964 18.388  42.867  1   136.51 ? 222 PRO C CD  1 
ATOM   8416 N  N   . ASP D 2 227 ? -70.904 16.235  41.46   1   147.64 ? 223 ASP C N   1 
ATOM   8417 C  CA  . ASP D 2 227 ? -72.098 15.53   41.996  1   148.39 ? 223 ASP C CA  1 
ATOM   8418 C  C   . ASP D 2 227 ? -72.347 14.29   41.14   1   143.93 ? 223 ASP C C   1 
ATOM   8419 O  O   . ASP D 2 227 ? -71.752 14.191  40.054  1   137.13 ? 223 ASP C O   1 
ATOM   8420 C  CB  . ASP D 2 227 ? -73.307 16.449  42.073  1   151.68 ? 223 ASP C CB  1 
ATOM   8421 C  CG  . ASP D 2 227 ? -73.843 16.965  40.747  1   152.55 ? 223 ASP C CG  1 
ATOM   8422 O  OD1 . ASP D 2 227 ? -73.081 16.964  39.761  1   161.08 ? 223 ASP C OD1 1 
ATOM   8423 O  OD2 . ASP D 2 227 ? -75.019 17.379  40.717  1   148.83 ? 223 ASP C OD2 1 
ATOM   8424 N  N   . GLU D 2 228 ? -73.196 13.385  41.617  1   151.3  ? 224 GLU C N   1 
ATOM   8425 C  CA  . GLU D 2 228 ? -73.452 12.125  40.88   1   153.88 ? 224 GLU C CA  1 
ATOM   8426 C  C   . GLU D 2 228 ? -73.878 12.461  39.444  1   157.24 ? 224 GLU C C   1 
ATOM   8427 O  O   . GLU D 2 228 ? -73.494 11.715  38.53   1   158.96 ? 224 GLU C O   1 
ATOM   8428 C  CB  . GLU D 2 228 ? -74.5   11.307  41.628  1   157.54 ? 224 GLU C CB  1 
ATOM   8429 C  CG  . GLU D 2 228 ? -74.009 10.81   42.983  1   157.07 ? 224 GLU C CG  1 
ATOM   8430 C  CD  . GLU D 2 228 ? -72.875 9.813   42.857  1   155.51 ? 224 GLU C CD  1 
ATOM   8431 O  OE1 . GLU D 2 228 ? -73.149 8.658   42.476  1   157.32 ? 224 GLU C OE1 1 
ATOM   8432 O  OE2 . GLU D 2 228 ? -71.72  10.189  43.141  1   148.22 ? 224 GLU C OE2 1 
ATOM   8433 N  N   . VAL D 2 229 ? -74.629 13.543  39.246  1   156.92 ? 225 VAL C N   1 
ATOM   8434 C  CA  . VAL D 2 229 ? -75.139 13.842  37.874  1   150.62 ? 225 VAL C CA  1 
ATOM   8435 C  C   . VAL D 2 229 ? -73.953 14.188  36.957  1   142.76 ? 225 VAL C C   1 
ATOM   8436 O  O   . VAL D 2 229 ? -74.058 13.931  35.74   1   134.11 ? 225 VAL C O   1 
ATOM   8437 C  CB  . VAL D 2 229 ? -76.21  14.95   37.914  1   148    ? 225 VAL C CB  1 
ATOM   8438 C  CG1 . VAL D 2 229 ? -76.653 15.354  36.514  1   144.36 ? 225 VAL C CG1 1 
ATOM   8439 C  CG2 . VAL D 2 229 ? -77.409 14.587  38.783  1   142.6  ? 225 VAL C CG2 1 
ATOM   8440 N  N   . VAL D 2 230 ? -72.865 14.724  37.521  1   144.87 ? 226 VAL C N   1 
ATOM   8441 C  CA  . VAL D 2 230 ? -71.647 15.063  36.726  1   137.82 ? 226 VAL C CA  1 
ATOM   8442 C  C   . VAL D 2 230 ? -70.665 13.891  36.824  1   132.46 ? 226 VAL C C   1 
ATOM   8443 O  O   . VAL D 2 230 ? -70.168 13.443  35.772  1   123.82 ? 226 VAL C O   1 
ATOM   8444 C  CB  . VAL D 2 230 ? -71.014 16.359  37.26   1   131.97 ? 226 VAL C CB  1 
ATOM   8445 C  CG1 . VAL D 2 230 ? -69.521 16.441  36.965  1   125.03 ? 226 VAL C CG1 1 
ATOM   8446 C  CG2 . VAL D 2 230 ? -71.734 17.594  36.735  1   126.4  ? 226 VAL C CG2 1 
ATOM   8447 N  N   . TRP D 2 231 ? -70.421 13.407  38.043  1   136.78 ? 227 TRP C N   1 
ATOM   8448 C  CA  . TRP D 2 231 ? -69.472 12.289  38.265  1   136.64 ? 227 TRP C CA  1 
ATOM   8449 C  C   . TRP D 2 231 ? -70.19  11.184  39.022  1   140.02 ? 227 TRP C C   1 
ATOM   8450 O  O   . TRP D 2 231 ? -70.142 11.168  40.265  1   142.32 ? 227 TRP C O   1 
ATOM   8451 C  CB  . TRP D 2 231 ? -68.26  12.795  39.053  1   137.58 ? 227 TRP C CB  1 
ATOM   8452 C  CG  . TRP D 2 231 ? -67.141 11.802  39.215  1   141.72 ? 227 TRP C CG  1 
ATOM   8453 C  CD1 . TRP D 2 231 ? -67.113 10.501  38.81   1   137.18 ? 227 TRP C CD1 1 
ATOM   8454 C  CD2 . TRP D 2 231 ? -65.87  12.049  39.853  1   143.48 ? 227 TRP C CD2 1 
ATOM   8455 N  NE1 . TRP D 2 231 ? -65.917 9.925   39.143  1   133.64 ? 227 TRP C NE1 1 
ATOM   8456 C  CE2 . TRP D 2 231 ? -65.136 10.847  39.785  1   134.96 ? 227 TRP C CE2 1 
ATOM   8457 C  CE3 . TRP D 2 231 ? -65.287 13.161  40.47   1   143.96 ? 227 TRP C CE3 1 
ATOM   8458 C  CZ2 . TRP D 2 231 ? -63.852 10.732  40.31   1   129.32 ? 227 TRP C CZ2 1 
ATOM   8459 C  CZ3 . TRP D 2 231 ? -64.019 13.044  40.99   1   135.35 ? 227 TRP C CZ3 1 
ATOM   8460 C  CH2 . TRP D 2 231 ? -63.313 11.845  40.911  1   135.77 ? 227 TRP C CH2 1 
ATOM   8461 N  N   . PRO D 2 232 ? -70.868 10.254  38.325  1   142.91 ? 228 PRO C N   1 
ATOM   8462 C  CA  . PRO D 2 232 ? -71.509 9.141   39      1   141.94 ? 228 PRO C CA  1 
ATOM   8463 C  C   . PRO D 2 232 ? -70.447 8.416   39.786  1   138.99 ? 228 PRO C C   1 
ATOM   8464 O  O   . PRO D 2 232 ? -69.511 7.864   39.183  1   137.75 ? 228 PRO C O   1 
ATOM   8465 C  CB  . PRO D 2 232 ? -72.051 8.301   37.85   1   140.58 ? 228 PRO C CB  1 
ATOM   8466 C  CG  . PRO D 2 232 ? -72.182 9.277   36.704  1   143.41 ? 228 PRO C CG  1 
ATOM   8467 C  CD  . PRO D 2 232 ? -71.026 10.241  36.885  1   143.51 ? 228 PRO C CD  1 
ATOM   8468 N  N   . GLY D 2 233 ? -70.575 8.423   41.109  1   138.63 ? 229 GLY C N   1 
ATOM   8469 C  CA  . GLY D 2 233 ? -69.612 7.704   41.959  1   138.11 ? 229 GLY C CA  1 
ATOM   8470 C  C   . GLY D 2 233 ? -68.866 8.663   42.857  1   139.51 ? 229 GLY C C   1 
ATOM   8471 O  O   . GLY D 2 233 ? -68.368 8.22    43.906  1   136.77 ? 229 GLY C O   1 
ATOM   8472 N  N   . VAL D 2 234 ? -68.806 9.938   42.478  1   139.86 ? 230 VAL C N   1 
ATOM   8473 C  CA  . VAL D 2 234 ? -68.011 10.916  43.275  1   135.44 ? 230 VAL C CA  1 
ATOM   8474 C  C   . VAL D 2 234 ? -68.375 10.774  44.763  1   140.28 ? 230 VAL C C   1 
ATOM   8475 O  O   . VAL D 2 234 ? -67.452 10.806  45.589  1   142.41 ? 230 VAL C O   1 
ATOM   8476 C  CB  . VAL D 2 234 ? -68.198 12.363  42.777  1   130.46 ? 230 VAL C CB  1 
ATOM   8477 C  CG1 . VAL D 2 234 ? -69.618 12.877  42.965  1   133.88 ? 230 VAL C CG1 1 
ATOM   8478 C  CG2 . VAL D 2 234 ? -67.195 13.308  43.423  1   125.04 ? 230 VAL C CG2 1 
ATOM   8479 N  N   . THR D 2 235 ? -69.654 10.59   45.096  1   139.43 ? 231 THR C N   1 
ATOM   8480 C  CA  . THR D 2 235 ? -70.068 10.557  46.518  1   137.3  ? 231 THR C CA  1 
ATOM   8481 C  C   . THR D 2 235 ? -69.551 9.304   47.191  1   136.6  ? 231 THR C C   1 
ATOM   8482 O  O   . THR D 2 235 ? -69.336 9.341   48.418  1   135.5  ? 231 THR C O   1 
ATOM   8483 C  CB  . THR D 2 235 ? -71.589 10.665  46.598  1   135.39 ? 231 THR C CB  1 
ATOM   8484 O  OG1 . THR D 2 235 ? -72.071 9.554   45.85   1   132.24 ? 231 THR C OG1 1 
ATOM   8485 C  CG2 . THR D 2 235 ? -72.101 11.969  46.016  1   130.22 ? 231 THR C CG2 1 
ATOM   8486 N  N   . SER D 2 236 ? -69.356 8.23    46.428  1   134.12 ? 232 SER C N   1 
ATOM   8487 C  CA  . SER D 2 236 ? -68.913 6.941   47.016  1   131.31 ? 232 SER C CA  1 
ATOM   8488 C  C   . SER D 2 236 ? -67.382 6.891   47.046  1   132.09 ? 232 SER C C   1 
ATOM   8489 O  O   . SER D 2 236 ? -66.831 5.905   47.576  1   130.51 ? 232 SER C O   1 
ATOM   8490 C  CB  . SER D 2 236 ? -69.484 5.784   46.249  1   124.97 ? 232 SER C CB  1 
ATOM   8491 O  OG  . SER D 2 236 ? -68.997 5.779   44.915  1   123.06 ? 232 SER C OG  1 
ATOM   8492 N  N   . MET D 2 237 ? -66.699 7.779   46.454  1   134.86 ? 233 MET C N   1 
ATOM   8493 C  CA  . MET D 2 237 ? -65.218 7.757   46.442  1   142.47 ? 233 MET C CA  1 
ATOM   8494 C  C   . MET D 2 237 ? -64.69  7.755   47.886  1   143.24 ? 233 MET C C   1 
ATOM   8495 O  O   . MET D 2 237 ? -65.238 8.488   48.734  1   148.03 ? 233 MET C O   1 
ATOM   8496 C  CB  . MET D 2 237 ? -64.674 8.969   45.682  1   149.98 ? 233 MET C CB  1 
ATOM   8497 C  CG  . MET D 2 237 ? -65.175 9.081   44.257  1   152.36 ? 233 MET C CG  1 
ATOM   8498 S  SD  . MET D 2 237 ? -64.433 7.925   43.09   1   152.26 ? 233 MET C SD  1 
ATOM   8499 C  CE  . MET D 2 237 ? -65.657 6.611   43.018  1   151.71 ? 233 MET C CE  1 
ATOM   8500 N  N   . PRO D 2 238 ? -63.591 7.027   48.221  1   140.58 ? 234 PRO C N   1 
ATOM   8501 C  CA  . PRO D 2 238 ? -63.138 6.923   49.606  1   144.78 ? 234 PRO C CA  1 
ATOM   8502 C  C   . PRO D 2 238 ? -63.019 8.188   50.458  1   149.56 ? 234 PRO C C   1 
ATOM   8503 O  O   . PRO D 2 238 ? -63.366 8.126   51.652  1   146.57 ? 234 PRO C O   1 
ATOM   8504 C  CB  . PRO D 2 238 ? -61.755 6.275   49.414  1   137.82 ? 234 PRO C CB  1 
ATOM   8505 C  CG  . PRO D 2 238 ? -61.951 5.347   48.253  1   132.75 ? 234 PRO C CG  1 
ATOM   8506 C  CD  . PRO D 2 238 ? -62.696 6.265   47.317  1   132.8  ? 234 PRO C CD  1 
ATOM   8507 N  N   . ASP D 2 239 ? -62.523 9.291   49.895  1   151.4  ? 235 ASP C N   1 
ATOM   8508 C  CA  . ASP D 2 239 ? -62.278 10.499  50.732  1   146.98 ? 235 ASP C CA  1 
ATOM   8509 C  C   . ASP D 2 239 ? -63.19  11.656  50.31   1   148.15 ? 235 ASP C C   1 
ATOM   8510 O  O   . ASP D 2 239 ? -62.888 12.807  50.684  1   148.01 ? 235 ASP C O   1 
ATOM   8511 C  CB  . ASP D 2 239 ? -60.808 10.885  50.709  1   140.15 ? 235 ASP C CB  1 
ATOM   8512 C  CG  . ASP D 2 239 ? -60.433 12.052  51.609  1   148.58 ? 235 ASP C CG  1 
ATOM   8513 O  OD1 . ASP D 2 239 ? -61.336 12.574  52.294  1   144.97 ? 235 ASP C OD1 1 
ATOM   8514 O  OD2 . ASP D 2 239 ? -59.242 12.428  51.616  1   149.08 ? 235 ASP C OD2 1 
ATOM   8515 N  N   . TYR D 2 240 ? -64.262 11.376  49.57   1   145.68 ? 236 TYR C N   1 
ATOM   8516 C  CA  . TYR D 2 240 ? -65.226 12.455  49.235  1   144.13 ? 236 TYR C CA  1 
ATOM   8517 C  C   . TYR D 2 240 ? -65.941 12.852  50.51   1   155.64 ? 236 TYR C C   1 
ATOM   8518 O  O   . TYR D 2 240 ? -66.233 11.958  51.331  1   157.37 ? 236 TYR C O   1 
ATOM   8519 C  CB  . TYR D 2 240 ? -66.246 11.964  48.21   1   139.26 ? 236 TYR C CB  1 
ATOM   8520 C  CG  . TYR D 2 240 ? -67.4   12.924  47.952  1   138.77 ? 236 TYR C CG  1 
ATOM   8521 C  CD1 . TYR D 2 240 ? -68.587 12.831  48.668  1   138.2  ? 236 TYR C CD1 1 
ATOM   8522 C  CD2 . TYR D 2 240 ? -67.297 13.923  46.995  1   133.58 ? 236 TYR C CD2 1 
ATOM   8523 C  CE1 . TYR D 2 240 ? -69.635 13.705  48.441  1   134.76 ? 236 TYR C CE1 1 
ATOM   8524 C  CE2 . TYR D 2 240 ? -68.34  14.8    46.754  1   131.5  ? 236 TYR C CE2 1 
ATOM   8525 C  CZ  . TYR D 2 240 ? -69.512 14.69   47.479  1   135.42 ? 236 TYR C CZ  1 
ATOM   8526 O  OH  . TYR D 2 240 ? -70.544 15.552  47.252  1   137.73 ? 236 TYR C OH  1 
ATOM   8527 N  N   . LYS D 2 241 ? -66.246 14.143  50.669  1   160.88 ? 237 LYS C N   1 
ATOM   8528 C  CA  . LYS D 2 241 ? -67.019 14.569  51.862  1   156.69 ? 237 LYS C CA  1 
ATOM   8529 C  C   . LYS D 2 241 ? -67.64  15.957  51.684  1   157.18 ? 237 LYS C C   1 
ATOM   8530 O  O   . LYS D 2 241 ? -67.012 16.802  51.019  1   161.43 ? 237 LYS C O   1 
ATOM   8531 C  CB  . LYS D 2 241 ? -66.106 14.593  53.092  1   155.81 ? 237 LYS C CB  1 
ATOM   8532 C  CG  . LYS D 2 241 ? -65.582 13.25   53.576  1   154.78 ? 237 LYS C CG  1 
ATOM   8533 C  CD  . LYS D 2 241 ? -64.668 13.392  54.786  1   146    ? 237 LYS C CD  1 
ATOM   8534 C  CE  . LYS D 2 241 ? -64.168 12.072  55.281  1   143.77 ? 237 LYS C CE  1 
ATOM   8535 N  NZ  . LYS D 2 241 ? -63.271 12.216  56.429  1   143.27 ? 237 LYS C NZ  1 
ATOM   8536 N  N   . PRO D 2 242 ? -68.838 16.223  52.253  1   153.98 ? 238 PRO C N   1 
ATOM   8537 C  CA  . PRO D 2 242 ? -69.434 17.565  52.26   1   148.76 ? 238 PRO C CA  1 
ATOM   8538 C  C   . PRO D 2 242 ? -68.499 18.672  52.767  1   138.56 ? 238 PRO C C   1 
ATOM   8539 O  O   . PRO D 2 242 ? -68.049 19.517  51.959  1   122.89 ? 238 PRO C O   1 
ATOM   8540 C  CB  . PRO D 2 242 ? -70.638 17.37   53.202  1   152.18 ? 238 PRO C CB  1 
ATOM   8541 C  CG  . PRO D 2 242 ? -70.992 15.911  53.055  1   150.36 ? 238 PRO C CG  1 
ATOM   8542 C  CD  . PRO D 2 242 ? -69.626 15.251  53.032  1   151.24 ? 238 PRO C CD  1 
ATOM   8543 N  N   . SER D 2 253 ? -66.549 28.506  32.4    1   117.26 ? 249 SER C N   1 
ATOM   8544 C  CA  . SER D 2 253 ? -66.53  29.976  32.634  1   118.2  ? 249 SER C CA  1 
ATOM   8545 C  C   . SER D 2 253 ? -65.269 30.577  32.01   1   121.16 ? 249 SER C C   1 
ATOM   8546 O  O   . SER D 2 253 ? -64.652 29.963  31.141  1   118.26 ? 249 SER C O   1 
ATOM   8547 C  CB  . SER D 2 253 ? -66.597 30.28   34.11   1   113.13 ? 249 SER C CB  1 
ATOM   8548 O  OG  . SER D 2 253 ? -67.48  29.402  34.792  1   107.15 ? 249 SER C OG  1 
ATOM   8549 N  N   . LYS D 2 254 ? -64.887 31.772  32.483  1   124.01 ? 250 LYS C N   1 
ATOM   8550 C  CA  . LYS D 2 254 ? -63.688 32.445  32.009  1   125.18 ? 250 LYS C CA  1 
ATOM   8551 C  C   . LYS D 2 254 ? -62.488 32.02   32.857  1   124.77 ? 250 LYS C C   1 
ATOM   8552 O  O   . LYS D 2 254 ? -61.766 32.853  33.411  1   114.33 ? 250 LYS C O   1 
ATOM   8553 C  CB  . LYS D 2 254 ? -63.932 33.956  31.914  1   122.37 ? 250 LYS C CB  1 
ATOM   8554 C  CG  . LYS D 2 254 ? -62.895 34.662  31.043  1   118.35 ? 250 LYS C CG  1 
ATOM   8555 C  CD  . LYS D 2 254 ? -63.301 35.985  30.399  1   117.59 ? 250 LYS C CD  1 
ATOM   8556 C  CE  . LYS D 2 254 ? -64.347 35.824  29.326  1   115.57 ? 250 LYS C CE  1 
ATOM   8557 N  NZ  . LYS D 2 254 ? -64.89  37.109  28.867  1   113.25 ? 250 LYS C NZ  1 
ATOM   8558 N  N   . VAL D 2 255 ? -62.3   30.694  32.924  1   126.77 ? 251 VAL C N   1 
ATOM   8559 C  CA  . VAL D 2 255 ? -61.161 30.05   33.559  1   126    ? 251 VAL C CA  1 
ATOM   8560 C  C   . VAL D 2 255 ? -59.889 30.428  32.802  1   120.12 ? 251 VAL C C   1 
ATOM   8561 O  O   . VAL D 2 255 ? -58.804 30.484  33.381  1   118.63 ? 251 VAL C O   1 
ATOM   8562 C  CB  . VAL D 2 255 ? -61.342 28.519  33.664  1   130.95 ? 251 VAL C CB  1 
ATOM   8563 C  CG1 . VAL D 2 255 ? -62.427 28.15   34.668  1   140.35 ? 251 VAL C CG1 1 
ATOM   8564 C  CG2 . VAL D 2 255 ? -61.623 27.837  32.326  1   123.44 ? 251 VAL C CG2 1 
ATOM   8565 N  N   . VAL D 2 256 ? -60.045 30.685  31.501  1   115.29 ? 252 VAL C N   1 
ATOM   8566 C  CA  . VAL D 2 256 ? -58.937 31.015  30.617  1   105.62 ? 252 VAL C CA  1 
ATOM   8567 C  C   . VAL D 2 256 ? -59.47  32      29.573  1   106.44 ? 252 VAL C C   1 
ATOM   8568 O  O   . VAL D 2 256 ? -59.976 31.588  28.527  1   102.33 ? 252 VAL C O   1 
ATOM   8569 C  CB  . VAL D 2 256 ? -58.279 29.759  29.992  1   95.75  ? 252 VAL C CB  1 
ATOM   8570 C  CG1 . VAL D 2 256 ? -57.341 29.024  30.95   1   85.06  ? 252 VAL C CG1 1 
ATOM   8571 C  CG2 . VAL D 2 256 ? -59.314 28.789  29.449  1   95.38  ? 252 VAL C CG2 1 
ATOM   8572 N  N   . PRO D 2 257 ? -59.437 33.326  29.865  1   112.82 ? 253 PRO C N   1 
ATOM   8573 C  CA  . PRO D 2 257 ? -59.907 34.35   28.922  1   115.52 ? 253 PRO C CA  1 
ATOM   8574 C  C   . PRO D 2 257 ? -59.425 34.225  27.472  1   116.44 ? 253 PRO C C   1 
ATOM   8575 O  O   . PRO D 2 257 ? -60.241 34.281  26.553  1   114.7  ? 253 PRO C O   1 
ATOM   8576 C  CB  . PRO D 2 257 ? -59.508 35.699  29.571  1   111.17 ? 253 PRO C CB  1 
ATOM   8577 C  CG  . PRO D 2 257 ? -59.407 35.374  31.046  1   109.5  ? 253 PRO C CG  1 
ATOM   8578 C  CD  . PRO D 2 257 ? -58.964 33.911  31.133  1   111.58 ? 253 PRO C CD  1 
ATOM   8579 N  N   . PRO D 2 258 ? -58.106 34.054  27.191  1   114.75 ? 254 PRO C N   1 
ATOM   8580 C  CA  . PRO D 2 258 ? -57.622 34.142  25.809  1   106    ? 254 PRO C CA  1 
ATOM   8581 C  C   . PRO D 2 258 ? -58.136 33.042  24.891  1   102.82 ? 254 PRO C C   1 
ATOM   8582 O  O   . PRO D 2 258 ? -57.856 33.078  23.699  1   104.91 ? 254 PRO C O   1 
ATOM   8583 C  CB  . PRO D 2 258 ? -56.083 34.104  25.92   1   102.17 ? 254 PRO C CB  1 
ATOM   8584 C  CG  . PRO D 2 258 ? -55.787 34.312  27.399  1   102.42 ? 254 PRO C CG  1 
ATOM   8585 C  CD  . PRO D 2 258 ? -57.012 33.813  28.155  1   106.78 ? 254 PRO C CD  1 
ATOM   8586 N  N   . LEU D 2 259 ? -58.889 32.085  25.452  1   101.31 ? 255 LEU C N   1 
ATOM   8587 C  CA  . LEU D 2 259 ? -59.064 30.773  24.841  1   98.31  ? 255 LEU C CA  1 
ATOM   8588 C  C   . LEU D 2 259 ? -60.392 30.674  24.096  1   107.18 ? 255 LEU C C   1 
ATOM   8589 O  O   . LEU D 2 259 ? -61.433 31.035  24.638  1   113.12 ? 255 LEU C O   1 
ATOM   8590 C  CB  . LEU D 2 259 ? -58.978 29.729  25.95   1   91.8   ? 255 LEU C CB  1 
ATOM   8591 C  CG  . LEU D 2 259 ? -58.698 28.299  25.485  1   87.38  ? 255 LEU C CG  1 
ATOM   8592 C  CD1 . LEU D 2 259 ? -57.42  28.208  24.668  1   86.18  ? 255 LEU C CD1 1 
ATOM   8593 C  CD2 . LEU D 2 259 ? -58.624 27.357  26.669  1   81.66  ? 255 LEU C CD2 1 
ATOM   8594 N  N   . ASP D 2 260 ? -60.346 30.131  22.871  1   111.36 ? 256 ASP C N   1 
ATOM   8595 C  CA  . ASP D 2 260 ? -61.494 30.073  21.968  1   112.59 ? 256 ASP C CA  1 
ATOM   8596 C  C   . ASP D 2 260 ? -62.535 29.047  22.442  1   109.17 ? 256 ASP C C   1 
ATOM   8597 O  O   . ASP D 2 260 ? -62.345 28.341  23.437  1   104.06 ? 256 ASP C O   1 
ATOM   8598 C  CB  . ASP D 2 260 ? -61.047 29.861  20.526  1   112.57 ? 256 ASP C CB  1 
ATOM   8599 C  CG  . ASP D 2 260 ? -60.305 28.554  20.254  1   115.24 ? 256 ASP C CG  1 
ATOM   8600 O  OD1 . ASP D 2 260 ? -59.271 28.305  20.919  1   111.82 ? 256 ASP C OD1 1 
ATOM   8601 O  OD2 . ASP D 2 260 ? -60.761 27.787  19.374  1   117.95 ? 256 ASP C OD2 1 
ATOM   8602 N  N   . GLU D 2 261 ? -63.642 28.963  21.69   1   107.04 ? 257 GLU C N   1 
ATOM   8603 C  CA  . GLU D 2 261 ? -64.793 28.124  22.003  1   108.79 ? 257 GLU C CA  1 
ATOM   8604 C  C   . GLU D 2 261 ? -64.392 26.644  21.989  1   105.18 ? 257 GLU C C   1 
ATOM   8605 O  O   . GLU D 2 261 ? -64.828 25.859  22.835  1   102.04 ? 257 GLU C O   1 
ATOM   8606 C  CB  . GLU D 2 261 ? -65.884 28.484  20.986  1   113.75 ? 257 GLU C CB  1 
ATOM   8607 C  CG  . GLU D 2 261 ? -67.219 27.763  21.179  1   118.83 ? 257 GLU C CG  1 
ATOM   8608 C  CD  . GLU D 2 261 ? -68.009 28.057  22.452  1   122.02 ? 257 GLU C CD  1 
ATOM   8609 O  OE1 . GLU D 2 261 ? -67.679 29.034  23.16   1   119.21 ? 257 GLU C OE1 1 
ATOM   8610 O  OE2 . GLU D 2 261 ? -68.955 27.298  22.748  1   124.39 ? 257 GLU C OE2 1 
ATOM   8611 N  N   . ASP D 2 262 ? -63.555 26.279  21.009  1   101.04 ? 258 ASP C N   1 
ATOM   8612 C  CA  . ASP D 2 262 ? -63.074 24.922  20.827  1   95.58  ? 258 ASP C CA  1 
ATOM   8613 C  C   . ASP D 2 262 ? -62.074 24.58   21.921  1   94.66  ? 258 ASP C C   1 
ATOM   8614 O  O   . ASP D 2 262 ? -62.18  23.519  22.538  1   97.75  ? 258 ASP C O   1 
ATOM   8615 C  CB  . ASP D 2 262 ? -62.458 24.739  19.452  1   95.16  ? 258 ASP C CB  1 
ATOM   8616 C  CG  . ASP D 2 262 ? -63.469 24.461  18.351  1   98.2   ? 258 ASP C CG  1 
ATOM   8617 O  OD1 . ASP D 2 262 ? -64.615 24.07   18.7    1   96.85  ? 258 ASP C OD1 1 
ATOM   8618 O  OD2 . ASP D 2 262 ? -63.1   24.637  17.167  1   97.54  ? 258 ASP C OD2 1 
ATOM   8619 N  N   . GLY D 2 263 ? -61.088 25.473  22.11   1   91     ? 259 GLY C N   1 
ATOM   8620 C  CA  . GLY D 2 263 ? -60.172 25.393  23.232  1   83.93  ? 259 GLY C CA  1 
ATOM   8621 C  C   . GLY D 2 263 ? -60.912 25.048  24.524  1   83.56  ? 259 GLY C C   1 
ATOM   8622 O  O   . GLY D 2 263 ? -60.58  24.065  25.178  1   82.63  ? 259 GLY C O   1 
ATOM   8623 N  N   . ARG D 2 264 ? -61.928 25.847  24.873  1   84.62  ? 260 ARG C N   1 
ATOM   8624 C  CA  . ARG D 2 264 ? -62.646 25.674  26.128  1   84.65  ? 260 ARG C CA  1 
ATOM   8625 C  C   . ARG D 2 264 ? -63.325 24.305  26.172  1   82.84  ? 260 ARG C C   1 
ATOM   8626 O  O   . ARG D 2 264 ? -63.401 23.684  27.225  1   81.86  ? 260 ARG C O   1 
ATOM   8627 C  CB  . ARG D 2 264 ? -63.624 26.829  26.387  1   91.46  ? 260 ARG C CB  1 
ATOM   8628 C  CG  . ARG D 2 264 ? -62.952 28.142  26.769  1   96.57  ? 260 ARG C CG  1 
ATOM   8629 C  CD  . ARG D 2 264 ? -63.881 29.289  27.162  1   100.89 ? 260 ARG C CD  1 
ATOM   8630 N  NE  . ARG D 2 264 ? -65.045 29.42   26.271  1   107.84 ? 260 ARG C NE  1 
ATOM   8631 C  CZ  . ARG D 2 264 ? -65.139 30.215  25.206  1   106.81 ? 260 ARG C CZ  1 
ATOM   8632 N  NH1 . ARG D 2 264 ? -64.085 30.905  24.811  1   108.21 ? 260 ARG C NH1 1 
ATOM   8633 N  NH2 . ARG D 2 264 ? -66.268 30.287  24.519  1   105.84 ? 260 ARG C NH2 1 
ATOM   8634 N  N   . SER D 2 265 ? -63.821 23.834  25.023  1   82.15  ? 261 SER C N   1 
ATOM   8635 C  CA  . SER D 2 265 ? -64.479 22.54   24.953  1   81.26  ? 261 SER C CA  1 
ATOM   8636 C  C   . SER D 2 265 ? -63.506 21.393  25.239  1   78.97  ? 261 SER C C   1 
ATOM   8637 O  O   . SER D 2 265 ? -63.786 20.509  26.053  1   77.22  ? 261 SER C O   1 
ATOM   8638 C  CB  . SER D 2 265 ? -65.129 22.369  23.626  1   84.66  ? 261 SER C CB  1 
ATOM   8639 O  OG  . SER D 2 265 ? -65.562 21.024  23.49   1   86.56  ? 261 SER C OG  1 
ATOM   8640 N  N   . LEU D 2 266 ? -62.365 21.401  24.543  1   76.8   ? 262 LEU C N   1 
ATOM   8641 C  CA  . LEU D 2 266 ? -61.331 20.399  24.737  1   75.93  ? 262 LEU C CA  1 
ATOM   8642 C  C   . LEU D 2 266 ? -60.89  20.345  26.208  1   74.54  ? 262 LEU C C   1 
ATOM   8643 O  O   . LEU D 2 266 ? -60.72  19.262  26.788  1   70.18  ? 262 LEU C O   1 
ATOM   8644 C  CB  . LEU D 2 266 ? -60.159 20.698  23.792  1   75.85  ? 262 LEU C CB  1 
ATOM   8645 C  CG  . LEU D 2 266 ? -58.911 19.809  23.958  1   69.28  ? 262 LEU C CG  1 
ATOM   8646 C  CD1 . LEU D 2 266 ? -59.261 18.341  23.826  1   67.54  ? 262 LEU C CD1 1 
ATOM   8647 C  CD2 . LEU D 2 266 ? -57.826 20.151  22.964  1   65.85  ? 262 LEU C CD2 1 
ATOM   8648 N  N   . LEU D 2 267 ? -60.697 21.533  26.8    1   72.56  ? 263 LEU C N   1 
ATOM   8649 C  CA  . LEU D 2 267 ? -60.15  21.652  28.14   1   68.7   ? 263 LEU C CA  1 
ATOM   8650 C  C   . LEU D 2 267 ? -61.078 20.924  29.107  1   70.02  ? 263 LEU C C   1 
ATOM   8651 O  O   . LEU D 2 267 ? -60.656 20.007  29.817  1   68.36  ? 263 LEU C O   1 
ATOM   8652 C  CB  . LEU D 2 267 ? -59.945 23.13   28.485  1   66.24  ? 263 LEU C CB  1 
ATOM   8653 C  CG  . LEU D 2 267 ? -59.321 23.437  29.853  1   65.42  ? 263 LEU C CG  1 
ATOM   8654 C  CD1 . LEU D 2 267 ? -58.132 22.531  30.234  1   62.5   ? 263 LEU C CD1 1 
ATOM   8655 C  CD2 . LEU D 2 267 ? -58.925 24.907  29.95   1   63.25  ? 263 LEU C CD2 1 
ATOM   8656 N  N   . SER D 2 268 ? -62.359 21.319  29.082  1   72.71  ? 264 SER C N   1 
ATOM   8657 C  CA  . SER D 2 268 ? -63.359 20.709  29.944  1   75.86  ? 264 SER C CA  1 
ATOM   8658 C  C   . SER D 2 268 ? -63.358 19.184  29.777  1   78.64  ? 264 SER C C   1 
ATOM   8659 O  O   . SER D 2 268 ? -63.438 18.454  30.766  1   80.59  ? 264 SER C O   1 
ATOM   8660 C  CB  . SER D 2 268 ? -64.715 21.311  29.724  1   76.35  ? 264 SER C CB  1 
ATOM   8661 O  OG  . SER D 2 268 ? -65.016 21.289  28.336  1   79.5   ? 264 SER C OG  1 
ATOM   8662 N  N   . GLN D 2 269 ? -63.225 18.702  28.533  1   77.65  ? 265 GLN C N   1 
ATOM   8663 C  CA  . GLN D 2 269 ? -63.236 17.27   28.268  1   77.9   ? 265 GLN C CA  1 
ATOM   8664 C  C   . GLN D 2 269 ? -61.999 16.598  28.869  1   75.8   ? 265 GLN C C   1 
ATOM   8665 O  O   . GLN D 2 269 ? -62.032 15.411  29.217  1   78.75  ? 265 GLN C O   1 
ATOM   8666 C  CB  . GLN D 2 269 ? -63.39  16.977  26.778  1   75.98  ? 265 GLN C CB  1 
ATOM   8667 C  CG  . GLN D 2 269 ? -64.766 17.315  26.223  1   78.95  ? 265 GLN C CG  1 
ATOM   8668 C  CD  . GLN D 2 269 ? -64.845 17.149  24.719  1   80.94  ? 265 GLN C CD  1 
ATOM   8669 O  OE1 . GLN D 2 269 ? -65.186 18.081  23.979  1   81.72  ? 265 GLN C OE1 1 
ATOM   8670 N  NE2 . GLN D 2 269 ? -64.532 15.949  24.249  1   78.71  ? 265 GLN C NE2 1 
ATOM   8671 N  N   . MET D 2 270 ? -60.899 17.351  28.981  1   72.01  ? 266 MET C N   1 
ATOM   8672 C  CA  . MET D 2 270 ? -59.686 16.793  29.566  1   68.21  ? 266 MET C CA  1 
ATOM   8673 C  C   . MET D 2 270 ? -59.809 16.824  31.081  1   67     ? 266 MET C C   1 
ATOM   8674 O  O   . MET D 2 270 ? -59.304 15.932  31.754  1   64.88  ? 266 MET C O   1 
ATOM   8675 C  CB  . MET D 2 270 ? -58.417 17.53   29.12   1   62.37  ? 266 MET C CB  1 
ATOM   8676 C  CG  . MET D 2 270 ? -58.079 17.224  27.703  1   61.29  ? 266 MET C CG  1 
ATOM   8677 S  SD  . MET D 2 270 ? -56.866 18.352  27.018  1   65.49  ? 266 MET C SD  1 
ATOM   8678 C  CE  . MET D 2 270 ? -55.356 17.41   27.31   1   57.45  ? 266 MET C CE  1 
ATOM   8679 N  N   . LEU D 2 271 ? -60.491 17.861  31.587  1   69.63  ? 267 LEU C N   1 
ATOM   8680 C  CA  . LEU D 2 271 ? -60.641 18.065  33.02   1   71.78  ? 267 LEU C CA  1 
ATOM   8681 C  C   . LEU D 2 271 ? -61.953 17.49   33.558  1   76.01  ? 267 LEU C C   1 
ATOM   8682 O  O   . LEU D 2 271 ? -62.375 17.845  34.654  1   75.3   ? 267 LEU C O   1 
ATOM   8683 C  CB  . LEU D 2 271 ? -60.484 19.556  33.31   1   70.75  ? 267 LEU C CB  1 
ATOM   8684 C  CG  . LEU D 2 271 ? -59.067 20.111  33.114  1   69.24  ? 267 LEU C CG  1 
ATOM   8685 C  CD1 . LEU D 2 271 ? -59.031 21.552  33.579  1   71.12  ? 267 LEU C CD1 1 
ATOM   8686 C  CD2 . LEU D 2 271 ? -57.968 19.279  33.797  1   64.09  ? 267 LEU C CD2 1 
ATOM   8687 N  N   . HIS D 2 272 ? -62.578 16.574  32.806  1   81.14  ? 268 HIS C N   1 
ATOM   8688 C  CA  . HIS D 2 272 ? -63.798 15.937  33.267  1   83.49  ? 268 HIS C CA  1 
ATOM   8689 C  C   . HIS D 2 272 ? -63.505 15.244  34.596  1   81.74  ? 268 HIS C C   1 
ATOM   8690 O  O   . HIS D 2 272 ? -62.418 14.712  34.807  1   78.71  ? 268 HIS C O   1 
ATOM   8691 C  CB  . HIS D 2 272 ? -64.379 15.002  32.202  1   87.32  ? 268 HIS C CB  1 
ATOM   8692 C  CG  . HIS D 2 272 ? -65.863 14.87   32.289  1   96.06  ? 268 HIS C CG  1 
ATOM   8693 N  ND1 . HIS D 2 272 ? -66.519 14.317  33.372  1   99.17  ? 268 HIS C ND1 1 
ATOM   8694 C  CD2 . HIS D 2 272 ? -66.82  15.265  31.431  1   100.47 ? 268 HIS C CD2 1 
ATOM   8695 C  CE1 . HIS D 2 272 ? -67.826 14.357  33.155  1   103.66 ? 268 HIS C CE1 1 
ATOM   8696 N  NE2 . HIS D 2 272 ? -68.033 14.932  31.983  1   107.33 ? 268 HIS C NE2 1 
ATOM   8697 N  N   . TYR D 2 273 ? -64.477 15.302  35.505  1   83.91  ? 269 TYR C N   1 
ATOM   8698 C  CA  . TYR D 2 273 ? -64.311 14.725  36.823  1   83.74  ? 269 TYR C CA  1 
ATOM   8699 C  C   . TYR D 2 273 ? -64.215 13.21   36.721  1   82.73  ? 269 TYR C C   1 
ATOM   8700 O  O   . TYR D 2 273 ? -63.252 12.621  37.199  1   79.49  ? 269 TYR C O   1 
ATOM   8701 C  CB  . TYR D 2 273 ? -65.521 15.132  37.655  1   91.63  ? 269 TYR C CB  1 
ATOM   8702 C  CG  . TYR D 2 273 ? -65.382 16.506  38.285  1   105.55 ? 269 TYR C CG  1 
ATOM   8703 C  CD1 . TYR D 2 273 ? -64.44  16.732  39.288  1   105.62 ? 269 TYR C CD1 1 
ATOM   8704 C  CD2 . TYR D 2 273 ? -66.207 17.565  37.902  1   114.34 ? 269 TYR C CD2 1 
ATOM   8705 C  CE1 . TYR D 2 273 ? -64.317 17.977  39.888  1   112.33 ? 269 TYR C CE1 1 
ATOM   8706 C  CE2 . TYR D 2 273 ? -66.1   18.811  38.509  1   121.64 ? 269 TYR C CE2 1 
ATOM   8707 C  CZ  . TYR D 2 273 ? -65.154 19.02   39.507  1   119.05 ? 269 TYR C CZ  1 
ATOM   8708 O  OH  . TYR D 2 273 ? -65.046 20.249  40.116  1   113.18 ? 269 TYR C OH  1 
ATOM   8709 N  N   . ASP D 2 274 ? -65.226 12.61   36.082  1   84.4   ? 270 ASP C N   1 
ATOM   8710 C  CA  . ASP D 2 274 ? -65.367 11.178  35.888  1   83.3   ? 270 ASP C CA  1 
ATOM   8711 C  C   . ASP D 2 274 ? -64.222 10.695  35      1   81.46  ? 270 ASP C C   1 
ATOM   8712 O  O   . ASP D 2 274 ? -64.114 11.135  33.856  1   83.22  ? 270 ASP C O   1 
ATOM   8713 C  CB  . ASP D 2 274 ? -66.737 10.909  35.28   1   85.8   ? 270 ASP C CB  1 
ATOM   8714 C  CG  . ASP D 2 274 ? -67.185 9.463   35.137  1   87.3   ? 270 ASP C CG  1 
ATOM   8715 O  OD1 . ASP D 2 274 ? -66.324 8.556   35.137  1   87.02  ? 270 ASP C OD1 1 
ATOM   8716 O  OD2 . ASP D 2 274 ? -68.411 9.261   35.023  1   91.39  ? 270 ASP C OD2 1 
ATOM   8717 N  N   . PRO D 2 275 ? -63.314 9.805   35.473  1   78.44  ? 271 PRO C N   1 
ATOM   8718 C  CA  . PRO D 2 275 ? -62.262 9.27    34.603  1   74.59  ? 271 PRO C CA  1 
ATOM   8719 C  C   . PRO D 2 275 ? -62.782 8.489   33.391  1   75.54  ? 271 PRO C C   1 
ATOM   8720 O  O   . PRO D 2 275 ? -62.098 8.423   32.366  1   73.03  ? 271 PRO C O   1 
ATOM   8721 C  CB  . PRO D 2 275 ? -61.438 8.39    35.547  1   74.59  ? 271 PRO C CB  1 
ATOM   8722 C  CG  . PRO D 2 275 ? -61.745 8.932   36.923  1   75.66  ? 271 PRO C CG  1 
ATOM   8723 C  CD  . PRO D 2 275 ? -63.217 9.31    36.856  1   78.57  ? 271 PRO C CD  1 
ATOM   8724 N  N   . ASN D 2 276 ? -64.011 7.957   33.488  1   77.22  ? 272 ASN C N   1 
ATOM   8725 C  CA  . ASN D 2 276 ? -64.594 7.217   32.379  1   79.33  ? 272 ASN C CA  1 
ATOM   8726 C  C   . ASN D 2 276 ? -65.084 8.147   31.274  1   79.22  ? 272 ASN C C   1 
ATOM   8727 O  O   . ASN D 2 276 ? -65.031 7.767   30.107  1   78.45  ? 272 ASN C O   1 
ATOM   8728 C  CB  . ASN D 2 276 ? -65.696 6.256   32.801  1   83.36  ? 272 ASN C CB  1 
ATOM   8729 C  CG  . ASN D 2 276 ? -65.22  5.241   33.81   1   85.5   ? 272 ASN C CG  1 
ATOM   8730 O  OD1 . ASN D 2 276 ? -64.078 4.765   33.743  1   85.16  ? 272 ASN C OD1 1 
ATOM   8731 N  ND2 . ASN D 2 276 ? -66.07  4.935   34.775  1   86.68  ? 272 ASN C ND2 1 
ATOM   8732 N  N   . LYS D 2 277 ? -65.579 9.335   31.648  1   81.1   ? 273 LYS C N   1 
ATOM   8733 C  CA  . LYS D 2 277 ? -66.103 10.304  30.695  1   83.52  ? 273 LYS C CA  1 
ATOM   8734 C  C   . LYS D 2 277 ? -64.996 11.235  30.203  1   79.45  ? 273 LYS C C   1 
ATOM   8735 O  O   . LYS D 2 277 ? -65.252 12.07   29.337  1   82.64  ? 273 LYS C O   1 
ATOM   8736 C  CB  . LYS D 2 277 ? -67.215 11.19   31.274  1   90.08  ? 273 LYS C CB  1 
ATOM   8737 C  CG  . LYS D 2 277 ? -68.663 10.704  31.14   1   100.66 ? 273 LYS C CG  1 
ATOM   8738 C  CD  . LYS D 2 277 ? -69.604 11.876  30.863  1   108.69 ? 273 LYS C CD  1 
ATOM   8739 C  CE  . LYS D 2 277 ? -71.086 11.61   30.966  1   114.85 ? 273 LYS C CE  1 
ATOM   8740 N  NZ  . LYS D 2 277 ? -71.588 11.889  32.314  1   115.72 ? 273 LYS C NZ  1 
ATOM   8741 N  N   . ARG D 2 278 ? -63.799 11.14   30.804  1   74.96  ? 274 ARG C N   1 
ATOM   8742 C  CA  . ARG D 2 278 ? -62.687 12.026  30.481  1   69.39  ? 274 ARG C CA  1 
ATOM   8743 C  C   . ARG D 2 278 ? -62.113 11.59   29.134  1   68.77  ? 274 ARG C C   1 
ATOM   8744 O  O   . ARG D 2 278 ? -61.894 10.394  28.899  1   69.13  ? 274 ARG C O   1 
ATOM   8745 C  CB  . ARG D 2 278 ? -61.653 11.962  31.613  1   66.82  ? 274 ARG C CB  1 
ATOM   8746 C  CG  . ARG D 2 278 ? -60.468 12.911  31.468  1   62.56  ? 274 ARG C CG  1 
ATOM   8747 C  CD  . ARG D 2 278 ? -59.552 12.914  32.686  1   58.24  ? 274 ARG C CD  1 
ATOM   8748 N  NE  . ARG D 2 278 ? -60.24  13.053  33.977  1   57.97  ? 274 ARG C NE  1 
ATOM   8749 C  CZ  . ARG D 2 278 ? -59.882 12.416  35.091  1   57.93  ? 274 ARG C CZ  1 
ATOM   8750 N  NH1 . ARG D 2 278 ? -58.791 11.67   35.129  1   56.9   ? 274 ARG C NH1 1 
ATOM   8751 N  NH2 . ARG D 2 278 ? -60.581 12.549  36.196  1   59.07  ? 274 ARG C NH2 1 
ATOM   8752 N  N   . ILE D 2 279 ? -61.856 12.571  28.266  1   66.3   ? 275 ILE C N   1 
ATOM   8753 C  CA  . ILE D 2 279 ? -61.461 12.286  26.899  1   67.91  ? 275 ILE C CA  1 
ATOM   8754 C  C   . ILE D 2 279 ? -60.131 11.517  26.852  1   69.06  ? 275 ILE C C   1 
ATOM   8755 O  O   . ILE D 2 279 ? -59.22  11.763  27.637  1   65.77  ? 275 ILE C O   1 
ATOM   8756 C  CB  . ILE D 2 279 ? -61.428 13.591  26.086  1   67.99  ? 275 ILE C CB  1 
ATOM   8757 C  CG1 . ILE D 2 279 ? -61.479 13.318  24.583  1   71.75  ? 275 ILE C CG1 1 
ATOM   8758 C  CG2 . ILE D 2 279 ? -60.256 14.488  26.473  1   63.76  ? 275 ILE C CG2 1 
ATOM   8759 C  CD1 . ILE D 2 279 ? -61.321 14.552  23.715  1   71.63  ? 275 ILE C CD1 1 
ATOM   8760 N  N   . SER D 2 280 ? -60.024 10.556  25.928  1   73.03  ? 276 SER C N   1 
ATOM   8761 C  CA  . SER D 2 280 ? -58.753 9.893   25.673  1   72.3   ? 276 SER C CA  1 
ATOM   8762 C  C   . SER D 2 280 ? -57.854 10.832  24.874  1   73.11  ? 276 SER C C   1 
ATOM   8763 O  O   . SER D 2 280 ? -58.344 11.777  24.249  1   72.94  ? 276 SER C O   1 
ATOM   8764 C  CB  . SER D 2 280 ? -58.948 8.6     24.933  1   72.7   ? 276 SER C CB  1 
ATOM   8765 O  OG  . SER D 2 280 ? -59.218 8.847   23.558  1   73.35  ? 276 SER C OG  1 
ATOM   8766 N  N   . ALA D 2 281 ? -56.542 10.559  24.908  1   71.87  ? 277 ALA C N   1 
ATOM   8767 C  CA  . ALA D 2 281 ? -55.597 11.262  24.056  1   69.35  ? 277 ALA C CA  1 
ATOM   8768 C  C   . ALA D 2 281 ? -55.963 11.038  22.584  1   69.83  ? 277 ALA C C   1 
ATOM   8769 O  O   . ALA D 2 281 ? -55.858 11.941  21.757  1   70.77  ? 277 ALA C O   1 
ATOM   8770 C  CB  . ALA D 2 281 ? -54.183 10.828  24.382  1   63.29  ? 277 ALA C CB  1 
ATOM   8771 N  N   . LYS D 2 282 ? -56.43  9.829   22.263  1   70.04  ? 278 LYS C N   1 
ATOM   8772 C  CA  . LYS D 2 282 ? -56.77  9.471   20.894  1   71.52  ? 278 LYS C CA  1 
ATOM   8773 C  C   . LYS D 2 282 ? -57.934 10.336  20.394  1   71.95  ? 278 LYS C C   1 
ATOM   8774 O  O   . LYS D 2 282 ? -57.834 10.979  19.352  1   70.12  ? 278 LYS C O   1 
ATOM   8775 C  CB  . LYS D 2 282 ? -57.065 7.969   20.88   1   72.58  ? 278 LYS C CB  1 
ATOM   8776 C  CG  . LYS D 2 282 ? -56.48  7.164   19.731  1   72.18  ? 278 LYS C CG  1 
ATOM   8777 C  CD  . LYS D 2 282 ? -56.532 5.705   20.171  1   75.25  ? 278 LYS C CD  1 
ATOM   8778 C  CE  . LYS D 2 282 ? -56.283 4.666   19.115  1   79.2   ? 278 LYS C CE  1 
ATOM   8779 N  NZ  . LYS D 2 282 ? -55.915 3.404   19.764  1   78.99  ? 278 LYS C NZ  1 
ATOM   8780 N  N   . ALA D 2 283 ? -59.034 10.363  21.155  1   74.55  ? 279 ALA C N   1 
ATOM   8781 C  CA  . ALA D 2 283 ? -60.158 11.253  20.89   1   77.08  ? 279 ALA C CA  1 
ATOM   8782 C  C   . ALA D 2 283 ? -59.677 12.696  20.731  1   78.56  ? 279 ALA C C   1 
ATOM   8783 O  O   . ALA D 2 283 ? -60.04  13.372  19.773  1   83.24  ? 279 ALA C O   1 
ATOM   8784 C  CB  . ALA D 2 283 ? -61.202 11.142  21.987  1   74.29  ? 279 ALA C CB  1 
ATOM   8785 N  N   . ALA D 2 284 ? -58.926 13.181  21.713  1   74.91  ? 280 ALA C N   1 
ATOM   8786 C  CA  . ALA D 2 284 ? -58.531 14.606  21.715  1   76.87  ? 280 ALA C CA  1 
ATOM   8787 C  C   . ALA D 2 284 ? -57.761 14.981  20.456  1   77.96  ? 280 ALA C C   1 
ATOM   8788 O  O   . ALA D 2 284 ? -57.75  16.169  20.102  1   80.57  ? 280 ALA C O   1 
ATOM   8789 C  CB  . ALA D 2 284 ? -57.716 14.882  22.949  1   77.18  ? 280 ALA C CB  1 
ATOM   8790 N  N   . LEU D 2 285 ? -57.14  14.01   19.8    1   76.95  ? 281 LEU C N   1 
ATOM   8791 C  CA  . LEU D 2 285 ? -56.289 14.36   18.638  1   77.81  ? 281 LEU C CA  1 
ATOM   8792 C  C   . LEU D 2 285 ? -57.177 14.763  17.451  1   83.57  ? 281 LEU C C   1 
ATOM   8793 O  O   . LEU D 2 285 ? -56.648 15.325  16.477  1   85.22  ? 281 LEU C O   1 
ATOM   8794 C  CB  . LEU D 2 285 ? -55.38  13.173  18.348  1   72.53  ? 281 LEU C CB  1 
ATOM   8795 C  CG  . LEU D 2 285 ? -54.097 13.116  19.181  1   70.25  ? 281 LEU C CG  1 
ATOM   8796 C  CD1 . LEU D 2 285 ? -53.291 11.877  18.853  1   67.9   ? 281 LEU C CD1 1 
ATOM   8797 C  CD2 . LEU D 2 285 ? -53.273 14.367  18.96   1   66.04  ? 281 LEU C CD2 1 
ATOM   8798 N  N   . ALA D 2 286 ? -58.483 14.545  17.57   1   85.74  ? 282 ALA C N   1 
ATOM   8799 C  CA  . ALA D 2 286 ? -59.427 14.916  16.495  1   88.78  ? 282 ALA C CA  1 
ATOM   8800 C  C   . ALA D 2 286 ? -60.088 16.251  16.816  1   92.06  ? 282 ALA C C   1 
ATOM   8801 O  O   . ALA D 2 286 ? -60.371 17.002  15.867  1   92.37  ? 282 ALA C O   1 
ATOM   8802 C  CB  . ALA D 2 286 ? -60.469 13.843  16.387  1   86.79  ? 282 ALA C CB  1 
ATOM   8803 N  N   . HIS D 2 287 ? -60.329 16.527  18.1    1   92.17  ? 283 HIS C N   1 
ATOM   8804 C  CA  . HIS D 2 287 ? -61.054 17.759  18.514  1   86.55  ? 283 HIS C CA  1 
ATOM   8805 C  C   . HIS D 2 287 ? -60.773 18.903  17.543  1   86.54  ? 283 HIS C C   1 
ATOM   8806 O  O   . HIS D 2 287 ? -59.599 19.243  17.28   1   85.28  ? 283 HIS C O   1 
ATOM   8807 C  CB  . HIS D 2 287 ? -60.731 18.13   19.965  1   80.2   ? 283 HIS C CB  1 
ATOM   8808 C  CG  . HIS D 2 287 ? -61.718 19.071  20.561  1   82.13  ? 283 HIS C CG  1 
ATOM   8809 N  ND1 . HIS D 2 287 ? -61.735 20.416  20.268  1   83.39  ? 283 HIS C ND1 1 
ATOM   8810 C  CD2 . HIS D 2 287 ? -62.722 18.862  21.414  1   81.91  ? 283 HIS C CD2 1 
ATOM   8811 C  CE1 . HIS D 2 287 ? -62.725 20.989  20.929  1   83.36  ? 283 HIS C CE1 1 
ATOM   8812 N  NE2 . HIS D 2 287 ? -63.335 20.065  21.635  1   83.26  ? 283 HIS C NE2 1 
ATOM   8813 N  N   . PRO D 2 288 ? -61.833 19.564  17.033  1   87.67  ? 284 PRO C N   1 
ATOM   8814 C  CA  . PRO D 2 288 ? -61.679 20.671  16.103  1   88.76  ? 284 PRO C CA  1 
ATOM   8815 C  C   . PRO D 2 288 ? -60.564 21.631  16.436  1   86.78  ? 284 PRO C C   1 
ATOM   8816 O  O   . PRO D 2 288 ? -60.03  22.268  15.52   1   91.06  ? 284 PRO C O   1 
ATOM   8817 C  CB  . PRO D 2 288 ? -63.043 21.357  16.194  1   89.73  ? 284 PRO C CB  1 
ATOM   8818 C  CG  . PRO D 2 288 ? -63.76  20.666  17.329  1   89.77  ? 284 PRO C CG  1 
ATOM   8819 C  CD  . PRO D 2 288 ? -63.214 19.258  17.314  1   89.48  ? 284 PRO C CD  1 
ATOM   8820 N  N   . PHE D 2 289 ? -60.226 21.757  17.716  1   81.67  ? 285 PHE C N   1 
ATOM   8821 C  CA  . PHE D 2 289 ? -59.195 22.742  18.115  1   82     ? 285 PHE C CA  1 
ATOM   8822 C  C   . PHE D 2 289 ? -57.971 22.559  17.234  1   85.4   ? 285 PHE C C   1 
ATOM   8823 O  O   . PHE D 2 289 ? -57.364 23.565  16.844  1   86.57  ? 285 PHE C O   1 
ATOM   8824 C  CB  . PHE D 2 289 ? -58.904 22.552  19.604  1   78.86  ? 285 PHE C CB  1 
ATOM   8825 C  CG  . PHE D 2 289 ? -57.846 23.496  20.154  1   75.39  ? 285 PHE C CG  1 
ATOM   8826 C  CD1 . PHE D 2 289 ? -57.998 24.872  20.055  1   76.48  ? 285 PHE C CD1 1 
ATOM   8827 C  CD2 . PHE D 2 289 ? -56.698 23.003  20.76   1   69.83  ? 285 PHE C CD2 1 
ATOM   8828 C  CE1 . PHE D 2 289 ? -57.031 25.727  20.554  1   74.81  ? 285 PHE C CE1 1 
ATOM   8829 C  CE2 . PHE D 2 289 ? -55.734 23.862  21.254  1   69.05  ? 285 PHE C CE2 1 
ATOM   8830 C  CZ  . PHE D 2 289 ? -55.903 25.221  21.152  1   73.81  ? 285 PHE C CZ  1 
ATOM   8831 N  N   . PHE D 2 290 ? -57.635 21.314  16.897  1   89.81  ? 286 PHE C N   1 
ATOM   8832 C  CA  . PHE D 2 290 ? -56.396 21.044  16.123  1   90.94  ? 286 PHE C CA  1 
ATOM   8833 C  C   . PHE D 2 290 ? -56.706 20.838  14.652  1   94.15  ? 286 PHE C C   1 
ATOM   8834 O  O   . PHE D 2 290 ? -56.092 19.962  14.02   1   95.36  ? 286 PHE C O   1 
ATOM   8835 C  CB  . PHE D 2 290 ? -55.747 19.77   16.656  1   83.13  ? 286 PHE C CB  1 
ATOM   8836 C  CG  . PHE D 2 290 ? -55.456 19.755  18.146  1   75.94  ? 286 PHE C CG  1 
ATOM   8837 C  CD1 . PHE D 2 290 ? -54.517 20.619  18.693  1   73.74  ? 286 PHE C CD1 1 
ATOM   8838 C  CD2 . PHE D 2 290 ? -56.108 18.86   18.982  1   73.72  ? 286 PHE C CD2 1 
ATOM   8839 C  CE1 . PHE D 2 290 ? -54.246 20.59   20.047  1   72.04  ? 286 PHE C CE1 1 
ATOM   8840 C  CE2 . PHE D 2 290 ? -55.832 18.84   20.334  1   72.32  ? 286 PHE C CE2 1 
ATOM   8841 C  CZ  . PHE D 2 290 ? -54.904 19.703  20.861  1   71.39  ? 286 PHE C CZ  1 
ATOM   8842 N  N   . GLN D 2 291 ? -57.627 21.626  14.108  1   98.85  ? 287 GLN C N   1 
ATOM   8843 C  CA  . GLN D 2 291 ? -57.949 21.524  12.667  1   103.68 ? 287 GLN C CA  1 
ATOM   8844 C  C   . GLN D 2 291 ? -56.979 22.414  11.891  1   100.06 ? 287 GLN C C   1 
ATOM   8845 O  O   . GLN D 2 291 ? -56.694 22.097  10.724  1   104.37 ? 287 GLN C O   1 
ATOM   8846 C  CB  . GLN D 2 291 ? -59.392 21.956  12.421  1   113.79 ? 287 GLN C CB  1 
ATOM   8847 C  CG  . GLN D 2 291 ? -60.429 21.019  13.026  1   122.95 ? 287 GLN C CG  1 
ATOM   8848 C  CD  . GLN D 2 291 ? -61.849 21.502  12.833  1   126.06 ? 287 GLN C CD  1 
ATOM   8849 O  OE1 . GLN D 2 291 ? -62.104 22.7    12.673  1   127.79 ? 287 GLN C OE1 1 
ATOM   8850 N  NE2 . GLN D 2 291 ? -62.788 20.568  12.847  1   118.05 ? 287 GLN C NE2 1 
ATOM   8851 N  N   . ASP D 2 292 ? -56.483 23.472  12.524  1   95.77  ? 288 ASP C N   1 
ATOM   8852 C  CA  . ASP D 2 292 ? -55.61  24.438  11.812  1   96.43  ? 288 ASP C CA  1 
ATOM   8853 C  C   . ASP D 2 292 ? -54.229 24.41   12.448  1   91.42  ? 288 ASP C C   1 
ATOM   8854 O  O   . ASP D 2 292 ? -53.532 25.441  12.398  1   91.71  ? 288 ASP C O   1 
ATOM   8855 C  CB  . ASP D 2 292 ? -56.195 25.836  11.895  1   101.39 ? 288 ASP C CB  1 
ATOM   8856 C  CG  . ASP D 2 292 ? -56.765 26.239  13.247  1   103.05 ? 288 ASP C CG  1 
ATOM   8857 O  OD1 . ASP D 2 292 ? -57.305 25.359  13.949  1   101.79 ? 288 ASP C OD1 1 
ATOM   8858 O  OD2 . ASP D 2 292 ? -56.671 27.435  13.584  1   102.53 ? 288 ASP C OD2 1 
ATOM   8859 N  N   . VAL D 2 293 ? -53.828 23.263  12.984  1   84.52  ? 289 VAL C N   1 
ATOM   8860 C  CA  . VAL D 2 293 ? -52.585 23.237  13.738  1   82.12  ? 289 VAL C CA  1 
ATOM   8861 C  C   . VAL D 2 293 ? -51.417 23.409  12.771  1   82.96  ? 289 VAL C C   1 
ATOM   8862 O  O   . VAL D 2 293 ? -51.433 22.824  11.69   1   86.75  ? 289 VAL C O   1 
ATOM   8863 C  CB  . VAL D 2 293 ? -52.417 21.975  14.605  1   77.24  ? 289 VAL C CB  1 
ATOM   8864 C  CG1 . VAL D 2 293 ? -52.535 20.684  13.798  1   75.6   ? 289 VAL C CG1 1 
ATOM   8865 C  CG2 . VAL D 2 293 ? -51.112 22.012  15.382  1   68.64  ? 289 VAL C CG2 1 
ATOM   8866 N  N   . THR D 2 294 ? -50.437 24.234  13.169  1   80.71  ? 290 THR C N   1 
ATOM   8867 C  CA  . THR D 2 294 ? -49.17  24.376  12.461  1   78.29  ? 290 THR C CA  1 
ATOM   8868 C  C   . THR D 2 294 ? -48.045 23.96   13.411  1   78.06  ? 290 THR C C   1 
ATOM   8869 O  O   . THR D 2 294 ? -48.315 23.44   14.495  1   76.15  ? 290 THR C O   1 
ATOM   8870 C  CB  . THR D 2 294 ? -48.977 25.778  11.862  1   79.19  ? 290 THR C CB  1 
ATOM   8871 O  OG1 . THR D 2 294 ? -49.004 26.763  12.894  1   77.42  ? 290 THR C OG1 1 
ATOM   8872 C  CG2 . THR D 2 294 ? -50.019 26.129  10.814  1   79.84  ? 290 THR C CG2 1 
ATOM   8873 N  N   . LYS D 2 295 ? -46.793 24.159  12.979  1   80.54  ? 291 LYS C N   1 
ATOM   8874 C  CA  . LYS D 2 295 ? -45.617 23.857  13.786  1   77.61  ? 291 LYS C CA  1 
ATOM   8875 C  C   . LYS D 2 295 ? -44.748 25.112  13.92   1   75.51  ? 291 LYS C C   1 
ATOM   8876 O  O   . LYS D 2 295 ? -43.638 25.147  13.402  1   76.74  ? 291 LYS C O   1 
ATOM   8877 C  CB  . LYS D 2 295 ? -44.826 22.682  13.188  1   74.46  ? 291 LYS C CB  1 
ATOM   8878 C  CG  . LYS D 2 295 ? -43.846 22.062  14.19   1   74.75  ? 291 LYS C CG  1 
ATOM   8879 C  CD  . LYS D 2 295 ? -43.173 20.748  13.817  1   76.69  ? 291 LYS C CD  1 
ATOM   8880 C  CE  . LYS D 2 295 ? -42.607 20.097  15.049  1   75.59  ? 291 LYS C CE  1 
ATOM   8881 N  NZ  . LYS D 2 295 ? -41.444 19.222  14.854  1   73.88  ? 291 LYS C NZ  1 
ATOM   8882 N  N   . PRO D 2 296 ? -45.178 26.178  14.64   1   73.31  ? 292 PRO C N   1 
ATOM   8883 C  CA  . PRO D 2 296 ? -44.352 27.382  14.768  1   74.84  ? 292 PRO C CA  1 
ATOM   8884 C  C   . PRO D 2 296 ? -43.068 27.094  15.534  1   76.34  ? 292 PRO C C   1 
ATOM   8885 O  O   . PRO D 2 296 ? -43.002 26.128  16.291  1   74.98  ? 292 PRO C O   1 
ATOM   8886 C  CB  . PRO D 2 296 ? -45.204 28.422  15.486  1   70.36  ? 292 PRO C CB  1 
ATOM   8887 C  CG  . PRO D 2 296 ? -46.576 27.783  15.596  1   71.29  ? 292 PRO C CG  1 
ATOM   8888 C  CD  . PRO D 2 296 ? -46.444 26.283  15.377  1   71.46  ? 292 PRO C CD  1 
ATOM   8889 N  N   . VAL D 2 297 ? -42.05  27.925  15.285  1   82.83  ? 293 VAL C N   1 
ATOM   8890 C  CA  . VAL D 2 297 ? -40.842 27.965  16.095  1   85.67  ? 293 VAL C CA  1 
ATOM   8891 C  C   . VAL D 2 297 ? -41.177 28.758  17.358  1   86.79  ? 293 VAL C C   1 
ATOM   8892 O  O   . VAL D 2 297 ? -42.074 29.597  17.342  1   93     ? 293 VAL C O   1 
ATOM   8893 C  CB  . VAL D 2 297 ? -39.601 28.509  15.348  1   82.79  ? 293 VAL C CB  1 
ATOM   8894 C  CG1 . VAL D 2 297 ? -39.026 27.489  14.369  1   76.78  ? 293 VAL C CG1 1 
ATOM   8895 C  CG2 . VAL D 2 297 ? -39.87  29.839  14.646  1   88.75  ? 293 VAL C CG2 1 
ATOM   8896 N  N   . PRO D 2 298 ? -40.545 28.472  18.514  1   84.9   ? 294 PRO C N   1 
ATOM   8897 C  CA  . PRO D 2 298 ? -40.758 29.292  19.708  1   85.56  ? 294 PRO C CA  1 
ATOM   8898 C  C   . PRO D 2 298 ? -39.82  30.494  19.68   1   94.73  ? 294 PRO C C   1 
ATOM   8899 O  O   . PRO D 2 298 ? -38.77  30.451  19.043  1   105.39 ? 294 PRO C O   1 
ATOM   8900 C  CB  . PRO D 2 298 ? -40.425 28.312  20.825  1   81.53  ? 294 PRO C CB  1 
ATOM   8901 C  CG  . PRO D 2 298 ? -39.349 27.425  20.227  1   84.18  ? 294 PRO C CG  1 
ATOM   8902 C  CD  . PRO D 2 298 ? -39.623 27.347  18.73   1   83.66  ? 294 PRO C CD  1 
ATOM   8903 N  N   . HIS D 2 299 ? -40.223 31.578  20.338  1   106.17 ? 295 HIS C N   1 
ATOM   8904 C  CA  . HIS D 2 299 ? -39.335 32.714  20.49   1   116.12 ? 295 HIS C CA  1 
ATOM   8905 C  C   . HIS D 2 299 ? -38.44  32.452  21.701  1   117.25 ? 295 HIS C C   1 
ATOM   8906 O  O   . HIS D 2 299 ? -38.917 32.505  22.835  1   114.72 ? 295 HIS C O   1 
ATOM   8907 C  CB  . HIS D 2 299 ? -40.143 34.012  20.613  1   127.95 ? 295 HIS C CB  1 
ATOM   8908 C  CG  . HIS D 2 299 ? -39.34  35.242  20.32   1   149.35 ? 295 HIS C CG  1 
ATOM   8909 N  ND1 . HIS D 2 299 ? -38.462 35.323  19.257  1   157.27 ? 295 HIS C ND1 1 
ATOM   8910 C  CD2 . HIS D 2 299 ? -39.285 36.433  20.936  1   151.71 ? 295 HIS C CD2 1 
ATOM   8911 C  CE1 . HIS D 2 299 ? -37.895 36.522  19.242  1   157.97 ? 295 HIS C CE1 1 
ATOM   8912 N  NE2 . HIS D 2 299 ? -38.383 37.213  20.252  1   160.91 ? 295 HIS C NE2 1 
ATOM   8913 N  N   . LEU D 2 300 ? -37.159 32.127  21.447  1   110.65 ? 296 LEU C N   1 
ATOM   8914 C  CA  . LEU D 2 300 ? -36.161 32.002  22.501  1   107.43 ? 296 LEU C CA  1 
ATOM   8915 C  C   . LEU D 2 300 ? -34.76  32.323  21.943  1   103.99 ? 296 LEU C C   1 
ATOM   8916 O  O   . LEU D 2 300 ? -33.817 32.363  22.761  1   99.27  ? 296 LEU C O   1 
ATOM   8917 C  CB  . LEU D 2 300 ? -36.22  30.657  23.233  1   107.44 ? 296 LEU C CB  1 
ATOM   8918 C  CG  . LEU D 2 300 ? -36.2   29.39   22.366  1   101.86 ? 296 LEU C CG  1 
ATOM   8919 C  CD1 . LEU D 2 300 ? -34.881 29.226  21.613  1   98.24  ? 296 LEU C CD1 1 
ATOM   8920 C  CD2 . LEU D 2 300 ? -36.545 28.125  23.165  1   85.24  ? 296 LEU C CD2 1 
HETATM 8921 C  C4  . HEW E 3 .   ? -34.186 -24.412 46.431  1   103.84 ? 601 HEW D C4  1 
HETATM 8922 C  C5  . HEW E 3 .   ? -33.977 -24.88  47.711  1   110.79 ? 601 HEW D C5  1 
HETATM 8923 N  N1  . HEW E 3 .   ? -30.436 -25.07  47.932  1   122.23 ? 601 HEW D N1  1 
HETATM 8924 N  N2  . HEW E 3 .   ? -32.744 -25.099 48.203  1   129.57 ? 601 HEW D N2  1 
HETATM 8925 C  C3  . HEW E 3 .   ? -33.075 -24.15  45.643  1   104.99 ? 601 HEW D C3  1 
HETATM 8926 C  C1  . HEW E 3 .   ? -31.657 -24.847 47.431  1   120.02 ? 601 HEW D C1  1 
HETATM 8927 C  C2  . HEW E 3 .   ? -31.804 -24.368 46.116  1   105.57 ? 601 HEW D C2  1 
HETATM 8928 BR BR1 . HEW E 3 .   ? -33.274 -23.461 43.88   1   106.28 ? 601 HEW D BR1 1 
HETATM 8929 C  C4  . HEW F 3 .   ? 13.387  -24.421 -8.273  1   58.9   ? 801 HEW A C4  1 
HETATM 8930 C  C5  . HEW F 3 .   ? 13.683  -23.626 -7.166  1   57.76  ? 801 HEW A C5  1 
HETATM 8931 N  N1  . HEW F 3 .   ? 15.947  -25.578 -5.311  1   53.8   ? 801 HEW A N1  1 
HETATM 8932 N  N2  . HEW F 3 .   ? 14.549  -24.026 -6.218  1   59.17  ? 801 HEW A N2  1 
HETATM 8933 C  C3  . HEW F 3 .   ? 14.002  -25.664 -8.368  1   58.91  ? 801 HEW A C3  1 
HETATM 8934 C  C1  . HEW F 3 .   ? 15.133  -25.243 -6.303  1   56.25  ? 801 HEW A C1  1 
HETATM 8935 C  C2  . HEW F 3 .   ? 14.879  -26.108 -7.391  1   55.83  ? 801 HEW A C2  1 
HETATM 8936 BR BR1 . HEW F 3 .   ? 13.634  -26.766 -9.874  1   61.68  ? 801 HEW A BR1 1 
HETATM 8937 C  C4  A HEW G 3 .   ? -10.422 -22.772 23.942  0.5 30     ? 802 HEW A C4  1 
HETATM 8938 C  C4  B HEW G 3 .   ? -10.428 -20.874 22.692  0.5 33.17  ? 802 HEW A C4  1 
HETATM 8939 C  C5  A HEW G 3 .   ? -11.148 -21.958 23.101  0.5 30     ? 802 HEW A C5  1 
HETATM 8940 C  C5  B HEW G 3 .   ? -10.978 -21.84  23.452  0.5 32.16  ? 802 HEW A C5  1 
HETATM 8941 N  N1  A HEW G 3 .   ? -8.876  -19.438 22.162  0.5 30     ? 802 HEW A N1  1 
HETATM 8942 N  N1  B HEW G 3 .   ? -8.301  -23.203 25.225  0.5 31.08  ? 802 HEW A N1  1 
HETATM 8943 N  N2  A HEW G 3 .   ? -10.64  -20.861 22.518  0.5 30     ? 802 HEW A N2  1 
HETATM 8944 N  N2  B HEW G 3 .   ? -10.257 -22.612 24.289  0.5 31.95  ? 802 HEW A N2  1 
HETATM 8945 C  C3  A HEW G 3 .   ? -9.104  -22.434 24.185  0.5 30     ? 802 HEW A C3  1 
HETATM 8946 C  C3  B HEW G 3 .   ? -9.063  -20.721 22.8    0.5 35.54  ? 802 HEW A C3  1 
HETATM 8947 C  C1  A HEW G 3 .   ? -9.356  -20.535 22.757  0.5 30     ? 802 HEW A C1  1 
HETATM 8948 C  C1  B HEW G 3 .   ? -8.947  -22.45  24.401  0.5 31.39  ? 802 HEW A C1  1 
HETATM 8949 C  C2  A HEW G 3 .   ? -8.547  -21.321 23.605  0.5 30     ? 802 HEW A C2  1 
HETATM 8950 C  C2  B HEW G 3 .   ? -8.293  -21.491 23.632  0.5 33.37  ? 802 HEW A C2  1 
HETATM 8951 BR BR1 A HEW G 3 .   ? -8.047  -23.516 25.333  0.5 30     ? 802 HEW A BR1 1 
HETATM 8952 BR BR1 B HEW G 3 .   ? -8.223  -19.406 21.743  0.5 44.99  ? 802 HEW A BR1 1 
HETATM 8953 C  C4  . HEW H 3 .   ? -7.565  -9.597  32.747  1   105.82 ? 803 HEW A C4  1 
HETATM 8954 C  C5  . HEW H 3 .   ? -8.313  -8.768  33.596  1   105.07 ? 803 HEW A C5  1 
HETATM 8955 N  N1  . HEW H 3 .   ? -10.282 -11.075 35.435  1   107.11 ? 803 HEW A N1  1 
HETATM 8956 N  N2  . HEW H 3 .   ? -9.204  -9.247  34.488  1   108.81 ? 803 HEW A N2  1 
HETATM 8957 C  C3  . HEW H 3 .   ? -7.768  -10.971 32.844  1   107.16 ? 803 HEW A C3  1 
HETATM 8958 C  C1  . HEW H 3 .   ? -9.396  -10.594 34.558  1   106.08 ? 803 HEW A C1  1 
HETATM 8959 C  C2  . HEW H 3 .   ? -8.688  -11.485 33.723  1   101.04 ? 803 HEW A C2  1 
HETATM 8960 BR BR1 . HEW H 3 .   ? -6.829  -12.194 31.725  1   114.4  ? 803 HEW A BR1 1 
HETATM 8961 C  C4  . HEW I 3 .   ? -18.928 -9.421  19.135  1   87.57  ? 804 HEW A C4  1 
HETATM 8962 C  C5  . HEW I 3 .   ? -18.738 -8.049  19.11   1   86.88  ? 804 HEW A C5  1 
HETATM 8963 N  N1  . HEW I 3 .   ? -19.597 -6.996  22.35   1   98.07  ? 804 HEW A N1  1 
HETATM 8964 N  N2  . HEW I 3 .   ? -18.971 -7.246  20.16   1   87.14  ? 804 HEW A N2  1 
HETATM 8965 C  C3  . HEW I 3 .   ? -19.38  -10.016 20.303  1   96.68  ? 804 HEW A C3  1 
HETATM 8966 C  C1  . HEW I 3 .   ? -19.407 -7.821  21.304  1   99.93  ? 804 HEW A C1  1 
HETATM 8967 C  C2  . HEW I 3 .   ? -19.618 -9.221  21.415  1   98.58  ? 804 HEW A C2  1 
HETATM 8968 BR BR1 . HEW I 3 .   ? -19.632 -11.918 20.363  1   112.44 ? 804 HEW A BR1 1 
HETATM 8969 C  C4  . HEW J 3 .   ? 10.004  -22.134 -4.752  1   129.61 ? 805 HEW A C4  1 
HETATM 8970 C  C5  . HEW J 3 .   ? 10.956  -21.545 -5.606  1   133.98 ? 805 HEW A C5  1 
HETATM 8971 N  N1  . HEW J 3 .   ? 9.627   -22.118 -8.824  1   93.15  ? 805 HEW A N1  1 
HETATM 8972 N  N2  . HEW J 3 .   ? 10.836  -21.542 -6.949  1   124.45 ? 805 HEW A N2  1 
HETATM 8973 C  C3  . HEW J 3 .   ? 8.874   -22.696 -5.334  1   126.73 ? 805 HEW A C3  1 
HETATM 8974 C  C1  . HEW J 3 .   ? 9.741   -22.121 -7.5    1   105.48 ? 805 HEW A C1  1 
HETATM 8975 C  C2  . HEW J 3 .   ? 8.739   -22.713 -6.703  1   115.55 ? 805 HEW A C2  1 
HETATM 8976 BR BR1 . HEW J 3 .   ? 7.509   -23.505 -4.27   1   122.3  ? 805 HEW A BR1 1 
HETATM 8977 C  C4  . HEW K 3 .   ? -19.213 17.427  2.828   1   89.47  ? 801 HEW B C4  1 
HETATM 8978 C  C5  . HEW K 3 .   ? -19.658 18.749  2.759   1   97.75  ? 801 HEW B C5  1 
HETATM 8979 N  N1  . HEW K 3 .   ? -18.416 20.264  5.692   1   83.35  ? 801 HEW B N1  1 
HETATM 8980 N  N2  . HEW K 3 .   ? -19.401 19.678  3.7     1   92.93  ? 801 HEW B N2  1 
HETATM 8981 C  C3  . HEW K 3 .   ? -18.447 17.069  3.924   1   102.32 ? 801 HEW B C3  1 
HETATM 8982 C  C1  . HEW K 3 .   ? -18.658 19.326  4.767   1   88.78  ? 801 HEW B C1  1 
HETATM 8983 C  C2  . HEW K 3 .   ? -18.167 18.009  4.909   1   96.66  ? 801 HEW B C2  1 
HETATM 8984 BR BR1 . HEW K 3 .   ? -17.784 15.281  4.08    1   111.16 ? 801 HEW B BR1 1 
HETATM 8985 C  C4  . HEW L 3 .   ? -15.399 18.026  3.059   1   120.24 ? 802 HEW B C4  1 
HETATM 8986 C  C5  . HEW L 3 .   ? -15.748 19.368  2.981   1   114.09 ? 802 HEW B C5  1 
HETATM 8987 N  N1  . HEW L 3 .   ? -15.977 19.923  -0.539  1   106.36 ? 802 HEW B N1  1 
HETATM 8988 N  N2  . HEW L 3 .   ? -15.944 19.989  1.802   1   123.56 ? 802 HEW B N2  1 
HETATM 8989 C  C3  . HEW L 3 .   ? -15.261 17.322  1.868   1   119.91 ? 802 HEW B C3  1 
HETATM 8990 C  C1  . HEW L 3 .   ? -15.792 19.295  0.635   1   120.04 ? 802 HEW B C1  1 
HETATM 8991 C  C2  . HEW L 3 .   ? -15.432 17.934  0.651   1   117.12 ? 802 HEW B C2  1 
HETATM 8992 BR BR1 . HEW L 3 .   ? -14.805 15.478  1.883   1   112.73 ? 802 HEW B BR1 1 
HETATM 8993 C  C4  A HEW M 3 .   ? -33.165 15.001  28.071  0.5 30     ? 701 HEW C C4  1 
HETATM 8994 C  C4  B HEW M 3 .   ? -33.053 15.162  27.935  0.5 35.44  ? 701 HEW C C4  1 
HETATM 8995 C  C5  A HEW M 3 .   ? -32.942 15.819  26.993  0.5 30     ? 701 HEW C C5  1 
HETATM 8996 C  C5  B HEW M 3 .   ? -33.432 13.985  28.552  0.5 35.75  ? 701 HEW C C5  1 
HETATM 8997 N  N1  A HEW M 3 .   ? -31.946 18.869  28.375  0.5 30     ? 701 HEW C N1  1 
HETATM 8998 N  N1  B HEW M 3 .   ? -33.502 14.634  31.902  0.5 31.75  ? 701 HEW C N1  1 
HETATM 8999 N  N2  A HEW M 3 .   ? -32.536 17.093  27.099  0.5 30     ? 701 HEW C N2  1 
HETATM 9000 N  N2  B HEW M 3 .   ? -33.551 13.81   29.885  0.5 32.83  ? 701 HEW C N2  1 
HETATM 9001 C  C3  A HEW M 3 .   ? -32.971 15.539  29.328  0.5 30     ? 701 HEW C C3  1 
HETATM 9002 C  C3  B HEW M 3 .   ? -32.812 16.211  28.78   0.5 36.8   ? 701 HEW C C3  1 
HETATM 9003 C  C1  A HEW M 3 .   ? -32.344 17.607  28.315  0.5 30     ? 701 HEW C C1  1 
HETATM 9004 C  C1  B HEW M 3 .   ? -33.342 14.846  30.648  0.5 32.11  ? 701 HEW C C1  1 
HETATM 9005 C  C2  A HEW M 3 .   ? -32.557 16.841  29.478  0.5 30     ? 701 HEW C C2  1 
HETATM 9006 C  C2  B HEW M 3 .   ? -32.937 16.087  30.135  0.5 34.66  ? 701 HEW C C2  1 
HETATM 9007 BR BR1 A HEW M 3 .   ? -33.275 14.464  30.86   0.5 30     ? 701 HEW C BR1 1 
HETATM 9008 BR BR1 B HEW M 3 .   ? -32.277 17.857  28.039  0.5 46.45  ? 701 HEW C BR1 1 
HETATM 9009 C  C4  . HEW N 3 .   ? -19.494 13.937  31.244  1   80.15  ? 702 HEW C C4  1 
HETATM 9010 C  C5  . HEW N 3 .   ? -18.386 13.54   30.525  1   83.71  ? 702 HEW C C5  1 
HETATM 9011 N  N1  . HEW N 3 .   ? -16.958 10.958  32.498  1   79.39  ? 702 HEW C N1  1 
HETATM 9012 N  N2  . HEW N 3 .   ? -17.553 12.566  30.946  1   86.83  ? 702 HEW C N2  1 
HETATM 9013 C  C3  . HEW N 3 .   ? -19.734 13.285  32.442  1   85.85  ? 702 HEW C C3  1 
HETATM 9014 C  C1  . HEW N 3 .   ? -17.8   11.927  32.118  1   81.69  ? 702 HEW C C1  1 
HETATM 9015 C  C2  . HEW N 3 .   ? -18.915 12.276  32.907  1   78.31  ? 702 HEW C C2  1 
HETATM 9016 BR BR1 . HEW N 3 .   ? -21.25  13.773  33.462  1   100.38 ? 702 HEW C BR1 1 
HETATM 9017 O  O   . HOH O 4 .   ? -40.863 -1.467  42.758  1   41.43  ? 701 HOH D O   1 
HETATM 9018 O  O   . HOH O 4 .   ? -27.067 -4.562  40.679  1   48.72  ? 702 HOH D O   1 
HETATM 9019 O  O   . HOH O 4 .   ? -43.18  -20.382 26.622  1   64.22  ? 703 HOH D O   1 
HETATM 9020 O  O   . HOH O 4 .   ? -47.874 -7.872  45.843  1   54.26  ? 704 HOH D O   1 
HETATM 9021 O  O   . HOH O 4 .   ? -45.493 -2.865  35.951  1   47.22  ? 705 HOH D O   1 
HETATM 9022 O  O   . HOH O 4 .   ? -28.264 -23.454 42.309  1   42.04  ? 706 HOH D O   1 
HETATM 9023 O  O   . HOH O 4 .   ? -24.785 -25.379 31.576  1   52.63  ? 707 HOH D O   1 
HETATM 9024 O  O   . HOH O 4 .   ? -19.632 -22.042 40.031  1   59.04  ? 708 HOH D O   1 
HETATM 9025 O  O   . HOH O 4 .   ? -51.141 -25.139 20.164  1   64.53  ? 709 HOH D O   1 
HETATM 9026 O  O   . HOH O 4 .   ? -21.396 -20.302 44.621  1   44.32  ? 710 HOH D O   1 
HETATM 9027 O  O   . HOH O 4 .   ? -46.147 -4.696  46.407  1   57.75  ? 711 HOH D O   1 
HETATM 9028 O  O   . HOH O 4 .   ? -32.725 -21.844 49.434  1   52.16  ? 712 HOH D O   1 
HETATM 9029 O  O   . HOH O 4 .   ? -38.44  -26.42  44.61   1   62.27  ? 713 HOH D O   1 
HETATM 9030 O  O   . HOH O 4 .   ? -44.337 -6.426  31.212  1   39.49  ? 714 HOH D O   1 
HETATM 9031 O  O   . HOH O 4 .   ? -34.6   -33.087 33.066  1   54.51  ? 715 HOH D O   1 
HETATM 9032 O  O   . HOH O 4 .   ? -22.03  -7.577  37.085  1   51.2   ? 716 HOH D O   1 
HETATM 9033 O  O   . HOH O 4 .   ? -50.557 -10.283 38.876  1   49.62  ? 717 HOH D O   1 
HETATM 9034 O  O   . HOH O 4 .   ? -42.235 -23.252 30.072  1   70.45  ? 718 HOH D O   1 
HETATM 9035 O  O   . HOH O 4 .   ? -51.307 -12.524 43.393  1   56.51  ? 719 HOH D O   1 
HETATM 9036 O  O   . HOH O 4 .   ? -33.706 -10.482 25.614  1   53.59  ? 720 HOH D O   1 
HETATM 9037 O  O   . HOH O 4 .   ? -47.872 -4.385  43.649  1   52.51  ? 721 HOH D O   1 
HETATM 9038 O  O   . HOH O 4 .   ? -19.022 -12.239 42.624  1   47.41  ? 722 HOH D O   1 
HETATM 9039 O  O   . HOH O 4 .   ? -28.267 -23.87  52.372  1   54.89  ? 723 HOH D O   1 
HETATM 9040 O  O   . HOH O 4 .   ? -21.052 -24.403 31.04   1   51.78  ? 724 HOH D O   1 
HETATM 9041 O  O   . HOH P 4 .   ? 14.194  -32.090 -2.103  1   46.25  ? 901 HOH A O   1 
HETATM 9042 O  O   . HOH P 4 .   ? 15.472  -31.364 -13.649 1   40.8   ? 902 HOH A O   1 
HETATM 9043 O  O   . HOH P 4 .   ? 4.12    -20.887 -0.864  1   39.14  ? 903 HOH A O   1 
HETATM 9044 O  O   . HOH P 4 .   ? -19.539 -38.871 23.649  1   62.5   ? 904 HOH A O   1 
HETATM 9045 O  O   . HOH P 4 .   ? -13.667 -11.013 -0.236  1   45.71  ? 905 HOH A O   1 
HETATM 9046 O  O   . HOH P 4 .   ? 7.091   -29.382 -17.692 1   51.87  ? 906 HOH A O   1 
HETATM 9047 O  O   . HOH P 4 .   ? -12.704 -28.821 -5.185  1   33.31  ? 907 HOH A O   1 
HETATM 9048 O  O   . HOH P 4 .   ? -21.833 -17.711 31.583  1   45.88  ? 908 HOH A O   1 
HETATM 9049 O  O   . HOH P 4 .   ? 7.39    -44.47  0.214   1   60.87  ? 909 HOH A O   1 
HETATM 9050 O  O   . HOH P 4 .   ? -2.118  -24.344 8.785   1   57.24  ? 910 HOH A O   1 
HETATM 9051 O  O   . HOH P 4 .   ? -4.889  -37.998 -4.513  1   46.28  ? 911 HOH A O   1 
HETATM 9052 O  O   . HOH P 4 .   ? -15.092 -27.279 0.944   1   34.57  ? 912 HOH A O   1 
HETATM 9053 O  O   . HOH P 4 .   ? -18.941 -24.514 19.253  1   36.56  ? 913 HOH A O   1 
HETATM 9054 O  O   . HOH P 4 .   ? -6.038  -24.398 6.09    1   37.7   ? 914 HOH A O   1 
HETATM 9055 O  O   . HOH P 4 .   ? -6.942  -12.965 7.981   1   45.41  ? 915 HOH A O   1 
HETATM 9056 O  O   . HOH P 4 .   ? -18.018 -18.539 17.012  1   46.88  ? 916 HOH A O   1 
HETATM 9057 O  O   . HOH P 4 .   ? 2.344   -29.919 13.248  1   55.73  ? 917 HOH A O   1 
HETATM 9058 O  O   . HOH P 4 .   ? -14.246 -27.141 -1.589  1   27.99  ? 918 HOH A O   1 
HETATM 9059 O  O   . HOH P 4 .   ? -2.934  -5.92   10.673  1   64.1   ? 919 HOH A O   1 
HETATM 9060 O  O   . HOH P 4 .   ? 0.287   -33.454 8.331   1   41.15  ? 920 HOH A O   1 
HETATM 9061 O  O   . HOH P 4 .   ? 15.101  -22.627 -3.965  1   59.23  ? 921 HOH A O   1 
HETATM 9062 O  O   . HOH P 4 .   ? -22.021 -18.914 27.49   1   44.4   ? 922 HOH A O   1 
HETATM 9063 O  O   . HOH P 4 .   ? -12.45  -10.341 2.777   1   35.72  ? 923 HOH A O   1 
HETATM 9064 O  O   . HOH P 4 .   ? 3.924   -41.215 3.524   1   45.21  ? 924 HOH A O   1 
HETATM 9065 O  O   . HOH P 4 .   ? -7.852  -16.561 -4.211  1   38.91  ? 925 HOH A O   1 
HETATM 9066 O  O   . HOH P 4 .   ? 5.842   -20.685 -15.08  1   65.96  ? 926 HOH A O   1 
HETATM 9067 O  O   . HOH P 4 .   ? -7.637  -18.621 10.458  1   34.85  ? 927 HOH A O   1 
HETATM 9068 O  O   . HOH P 4 .   ? -9.957  -28.908 -13.966 1   45.62  ? 928 HOH A O   1 
HETATM 9069 O  O   . HOH P 4 .   ? -21.806 -28.664 7.849   1   46.89  ? 929 HOH A O   1 
HETATM 9070 O  O   . HOH P 4 .   ? -12.295 -12.662 -9.297  1   48.91  ? 930 HOH A O   1 
HETATM 9071 O  O   . HOH P 4 .   ? -8.052  -33.221 -13.216 1   49.68  ? 931 HOH A O   1 
HETATM 9072 O  O   . HOH P 4 .   ? -3.626  -25.425 2.187   1   39.87  ? 932 HOH A O   1 
HETATM 9073 O  O   . HOH P 4 .   ? 1.794   -32.42  6.326   1   36.29  ? 933 HOH A O   1 
HETATM 9074 O  O   . HOH P 4 .   ? -16.183 -22.623 37.589  1   59.15  ? 934 HOH A O   1 
HETATM 9075 O  O   . HOH P 4 .   ? -1.379  -23.258 23.628  1   54.5   ? 935 HOH A O   1 
HETATM 9076 O  O   . HOH P 4 .   ? 12.200  -36.369 6.134   1   54.22  ? 936 HOH A O   1 
HETATM 9077 O  O   . HOH P 4 .   ? -2.86   -20.12  -5.69   1   31.69  ? 937 HOH A O   1 
HETATM 9078 O  O   . HOH P 4 .   ? -19.921 -9.304  10.423  1   41.24  ? 938 HOH A O   1 
HETATM 9079 O  O   . HOH P 4 .   ? -26.756 -20.709 8.3     1   54.71  ? 939 HOH A O   1 
HETATM 9080 O  O   . HOH P 4 .   ? 0.671   -37.528 -10.025 1   42.42  ? 940 HOH A O   1 
HETATM 9081 O  O   . HOH P 4 .   ? -7.927  -23.719 -4.44   1   37.23  ? 941 HOH A O   1 
HETATM 9082 O  O   . HOH P 4 .   ? -4.388  -8.809  5.293   1   56.75  ? 942 HOH A O   1 
HETATM 9083 O  O   . HOH P 4 .   ? -18.708 -6.139  25.897  1   70.27  ? 943 HOH A O   1 
HETATM 9084 O  O   . HOH P 4 .   ? -14.704 -12.007 -5.023  1   48.37  ? 944 HOH A O   1 
HETATM 9085 O  O   . HOH P 4 .   ? -18.679 -15.767 30.54   1   50.57  ? 945 HOH A O   1 
HETATM 9086 O  O   . HOH P 4 .   ? -3.075  -36.58  -6.23   1   50.77  ? 946 HOH A O   1 
HETATM 9087 O  O   . HOH P 4 .   ? -12.253 -28.924 -2.432  1   44.3   ? 947 HOH A O   1 
HETATM 9088 O  O   . HOH P 4 .   ? -11.186 -9.39   37.713  1   56.03  ? 948 HOH A O   1 
HETATM 9089 O  O   . HOH P 4 .   ? 4.648   -21.71  7.481   1   46.9   ? 949 HOH A O   1 
HETATM 9090 O  O   . HOH P 4 .   ? 1.205   -29.64  2.315   1   36.72  ? 950 HOH A O   1 
HETATM 9091 O  O   . HOH P 4 .   ? -23.311 -29.362 10.187  1   41.78  ? 951 HOH A O   1 
HETATM 9092 O  O   . HOH P 4 .   ? -12.392 -10.788 5.298   1   35.83  ? 952 HOH A O   1 
HETATM 9093 O  O   . HOH P 4 .   ? 6.477   -19.57  3.171   1   52.15  ? 953 HOH A O   1 
HETATM 9094 O  O   . HOH P 4 .   ? 2.472   -24.577 14.418  1   53.02  ? 954 HOH A O   1 
HETATM 9095 O  O   . HOH P 4 .   ? 12.029  -22.55  -1.579  1   52.34  ? 955 HOH A O   1 
HETATM 9096 O  O   . HOH P 4 .   ? -4.426  -19.533 -10.56  1   45.15  ? 956 HOH A O   1 
HETATM 9097 O  O   . HOH P 4 .   ? -22.501 -15.313 17.818  1   54.45  ? 957 HOH A O   1 
HETATM 9098 O  O   . HOH P 4 .   ? -19.301 -21.437 16.938  1   43.31  ? 958 HOH A O   1 
HETATM 9099 O  O   . HOH P 4 .   ? -2.588  -15.512 -3.667  1   48.41  ? 959 HOH A O   1 
HETATM 9100 O  O   . HOH P 4 .   ? -8.185  -10.333 -8.223  1   42.15  ? 960 HOH A O   1 
HETATM 9101 O  O   . HOH P 4 .   ? -12.685 -49.934 4.281   1   63.07  ? 961 HOH A O   1 
HETATM 9102 O  O   . HOH P 4 .   ? -16.468 -32.548 -4.321  1   49.25  ? 962 HOH A O   1 
HETATM 9103 O  O   . HOH P 4 .   ? 11.049  -20.914 1.021   1   53.14  ? 963 HOH A O   1 
HETATM 9104 O  O   . HOH P 4 .   ? -8.185  -12.056 37.543  1   60.56  ? 964 HOH A O   1 
HETATM 9105 O  O   . HOH P 4 .   ? -15.79  -41.871 -3.021  1   47.26  ? 965 HOH A O   1 
HETATM 9106 O  O   . HOH P 4 .   ? 13.52   -24.545 -15.955 1   45.55  ? 966 HOH A O   1 
HETATM 9107 O  O   . HOH P 4 .   ? -11.917 -22.884 -11.01  1   46.1   ? 967 HOH A O   1 
HETATM 9108 O  O   . HOH P 4 .   ? -22.767 -27.057 4.87    1   52.06  ? 968 HOH A O   1 
HETATM 9109 O  O   . HOH P 4 .   ? -13.784 -27.152 31.783  1   62.1   ? 969 HOH A O   1 
HETATM 9110 O  O   . HOH P 4 .   ? -5.389  -40.882 30.306  1   60.87  ? 970 HOH A O   1 
HETATM 9111 O  O   . HOH P 4 .   ? -4.291  -51.539 6.193   1   58.54  ? 971 HOH A O   1 
HETATM 9112 O  O   . HOH P 4 .   ? -9.964  -11.278 39.094  1   58.17  ? 972 HOH A O   1 
HETATM 9113 O  O   . HOH P 4 .   ? -10.526 -11.089 -10.018 1   45.66  ? 973 HOH A O   1 
HETATM 9114 O  O   . HOH P 4 .   ? -2.254  -8.505  8.733   1   50.24  ? 974 HOH A O   1 
HETATM 9115 O  O   . HOH P 4 .   ? -19.348 -37.186 15.985  1   63.23  ? 975 HOH A O   1 
HETATM 9116 O  O   . HOH P 4 .   ? -9.686  -19.218 18.795  1   60.62  ? 976 HOH A O   1 
HETATM 9117 O  O   . HOH P 4 .   ? -15.609 -44.294 -2.125  1   50.83  ? 977 HOH A O   1 
HETATM 9118 O  O   . HOH P 4 .   ? -18.068 -24.001 31.679  1   48.67  ? 978 HOH A O   1 
HETATM 9119 O  O   . HOH P 4 .   ? 12.208  -39.486 -10.214 1   50.71  ? 979 HOH A O   1 
HETATM 9120 O  O   . HOH P 4 .   ? -19.294 -31.435 23.349  1   50.38  ? 980 HOH A O   1 
HETATM 9121 O  O   . HOH P 4 .   ? -6.308  -25.352 -11.536 1   48.57  ? 981 HOH A O   1 
HETATM 9122 O  O   . HOH P 4 .   ? -16.081 -46.216 13.528  1   60.46  ? 982 HOH A O   1 
HETATM 9123 O  O   . HOH P 4 .   ? -4.243  -36.175 -8.452  1   33.44  ? 983 HOH A O   1 
HETATM 9124 O  O   . HOH P 4 .   ? -15.632 -28.16  -10.093 1   55.14  ? 984 HOH A O   1 
HETATM 9125 O  O   . HOH P 4 .   ? 5.194   -25.992 9.203   1   56.83  ? 985 HOH A O   1 
HETATM 9126 O  O   . HOH P 4 .   ? -9.221  -23.369 -12.715 1   68.93  ? 986 HOH A O   1 
HETATM 9127 O  O   . HOH P 4 .   ? -2.516  -19.132 -12.352 1   32.8   ? 987 HOH A O   1 
HETATM 9128 O  O   . HOH P 4 .   ? 0.151   -11.163 -1.566  1   40.17  ? 988 HOH A O   1 
HETATM 9129 O  O   . HOH P 4 .   ? -12.611 -22.574 37.787  1   57.87  ? 989 HOH A O   1 
HETATM 9130 O  O   . HOH P 4 .   ? -1.162  -17.943 -3.512  1   42.94  ? 990 HOH A O   1 
HETATM 9131 O  O   . HOH P 4 .   ? -5.338  -21.605 23.21   1   63.62  ? 991 HOH A O   1 
HETATM 9132 O  O   . HOH P 4 .   ? -19.433 -13.599 28.668  1   61.15  ? 992 HOH A O   1 
HETATM 9133 O  O   . HOH P 4 .   ? -27.287 -21.886 10.759  1   69.47  ? 993 HOH A O   1 
HETATM 9134 O  O   . HOH Q 4 .   ? -36.123 4.432   8.423   1   63.61  ? 901 HOH B O   1 
HETATM 9135 O  O   . HOH Q 4 .   ? -25.19  -5.306  3.37    1   60.82  ? 902 HOH B O   1 
HETATM 9136 O  O   . HOH Q 4 .   ? -30.429 21.681  11.361  1   62.48  ? 903 HOH B O   1 
HETATM 9137 O  O   . HOH Q 4 .   ? -5.665  -6.437  5.587   1   52.48  ? 904 HOH B O   1 
HETATM 9138 O  O   . HOH Q 4 .   ? -30.766 16.367  7.287   1   50.46  ? 905 HOH B O   1 
HETATM 9139 O  O   . HOH Q 4 .   ? -34.025 1.036   -25.962 1   64.21  ? 906 HOH B O   1 
HETATM 9140 O  O   . HOH Q 4 .   ? -29.178 0.788   -0.39   1   49.71  ? 907 HOH B O   1 
HETATM 9141 O  O   . HOH Q 4 .   ? -16.801 -8.356  -4.088  1   46.98  ? 908 HOH B O   1 
HETATM 9142 O  O   . HOH Q 4 .   ? -8.601  2.117   16.988  1   55.17  ? 909 HOH B O   1 
HETATM 9143 O  O   . HOH Q 4 .   ? -37.678 6.022   -6.283  1   56.57  ? 910 HOH B O   1 
HETATM 9144 O  O   . HOH Q 4 .   ? -18.006 -1.09   -7.995  1   50.38  ? 911 HOH B O   1 
HETATM 9145 O  O   . HOH Q 4 .   ? -6.452  -3.136  -3.98   1   43.09  ? 912 HOH B O   1 
HETATM 9146 O  O   . HOH Q 4 .   ? -26.536 15.528  11.838  1   54.28  ? 913 HOH B O   1 
HETATM 9147 O  O   . HOH Q 4 .   ? -4.315  -4.297  -0.856  1   48.74  ? 914 HOH B O   1 
HETATM 9148 O  O   . HOH Q 4 .   ? -32.503 -10.262 0.53    1   41.77  ? 915 HOH B O   1 
HETATM 9149 O  O   . HOH Q 4 .   ? -36.795 -13.727 -3.977  1   48.07  ? 916 HOH B O   1 
HETATM 9150 O  O   . HOH Q 4 .   ? -16.498 16.548  7.586   1   48.02  ? 917 HOH B O   1 
HETATM 9151 O  O   . HOH Q 4 .   ? -23.285 2.901   -26.145 1   56.33  ? 918 HOH B O   1 
HETATM 9152 O  O   . HOH Q 4 .   ? -24.356 24.67   10.687  1   53.64  ? 919 HOH B O   1 
HETATM 9153 O  O   . HOH Q 4 .   ? -19.42  -12.929 -0.718  1   48.73  ? 920 HOH B O   1 
HETATM 9154 O  O   . HOH Q 4 .   ? -27.143 10.736  -12.147 1   61.74  ? 921 HOH B O   1 
HETATM 9155 O  O   . HOH Q 4 .   ? -19.115 10.133  -8.462  1   48.4   ? 922 HOH B O   1 
HETATM 9156 O  O   . HOH Q 4 .   ? -26.424 10.912  -0.724  1   42.43  ? 923 HOH B O   1 
HETATM 9157 O  O   . HOH Q 4 .   ? -16.295 -8.329  1.447   1   35.47  ? 924 HOH B O   1 
HETATM 9158 O  O   . HOH Q 4 .   ? -28.147 6.05    19.219  1   62.22  ? 925 HOH B O   1 
HETATM 9159 O  O   . HOH Q 4 .   ? -18.302 -8.675  3.412   1   33.52  ? 926 HOH B O   1 
HETATM 9160 O  O   . HOH Q 4 .   ? -25.596 1.533   1.513   1   57.48  ? 927 HOH B O   1 
HETATM 9161 O  O   . HOH Q 4 .   ? -10.991 -19.688 -12.36  1   56.02  ? 928 HOH B O   1 
HETATM 9162 O  O   . HOH Q 4 .   ? -29.808 11.21   13.953  1   45.84  ? 929 HOH B O   1 
HETATM 9163 O  O   . HOH Q 4 .   ? -25.901 1.698   -3.194  1   46.03  ? 930 HOH B O   1 
HETATM 9164 O  O   . HOH Q 4 .   ? -17.564 21.39   8.089   1   71.27  ? 931 HOH B O   1 
HETATM 9165 O  O   . HOH Q 4 .   ? -9.768  7.633   -11.252 1   45.04  ? 932 HOH B O   1 
HETATM 9166 O  O   . HOH Q 4 .   ? -21.155 -2.094  -26.931 1   53.52  ? 933 HOH B O   1 
HETATM 9167 O  O   . HOH Q 4 .   ? -19.918 -11.004 3.099   1   48.29  ? 934 HOH B O   1 
HETATM 9168 O  O   . HOH Q 4 .   ? -30.933 -19.648 -5.128  1   54.42  ? 935 HOH B O   1 
HETATM 9169 O  O   . HOH Q 4 .   ? -22.942 -10.216 7.856   1   49.61  ? 936 HOH B O   1 
HETATM 9170 O  O   . HOH Q 4 .   ? -13.945 -21.61  -12.324 1   46.97  ? 937 HOH B O   1 
HETATM 9171 O  O   . HOH Q 4 .   ? -27.166 5.289   -1.716  1   42.76  ? 938 HOH B O   1 
HETATM 9172 O  O   . HOH Q 4 .   ? -12.093 9.286   -9.965  1   51.78  ? 939 HOH B O   1 
HETATM 9173 O  O   . HOH Q 4 .   ? -30.494 -12.264 -5.27   1   40.19  ? 940 HOH B O   1 
HETATM 9174 O  O   . HOH Q 4 .   ? -17.213 -10.864 -5.161  1   53.49  ? 941 HOH B O   1 
HETATM 9175 O  O   . HOH Q 4 .   ? -19.771 21.02   12.221  1   57.47  ? 942 HOH B O   1 
HETATM 9176 O  O   . HOH Q 4 .   ? -13.475 -5.259  -5.608  1   40.38  ? 943 HOH B O   1 
HETATM 9177 O  O   . HOH Q 4 .   ? -5.864  14.693  18.857  1   62.27  ? 944 HOH B O   1 
HETATM 9178 O  O   . HOH Q 4 .   ? -22.289 11.154  -12.141 1   50.87  ? 945 HOH B O   1 
HETATM 9179 O  O   . HOH Q 4 .   ? -22.884 -2.114  -1.991  1   44.71  ? 946 HOH B O   1 
HETATM 9180 O  O   . HOH Q 4 .   ? -24.805 -24.585 -1.702  1   41.04  ? 947 HOH B O   1 
HETATM 9181 O  O   . HOH Q 4 .   ? -24.679 -14.53  11.11   1   59.4   ? 948 HOH B O   1 
HETATM 9182 O  O   . HOH Q 4 .   ? -37.018 -2.861  -7.577  1   54.48  ? 949 HOH B O   1 
HETATM 9183 O  O   . HOH Q 4 .   ? -31.017 15.594  2.778   1   52.68  ? 950 HOH B O   1 
HETATM 9184 O  O   . HOH Q 4 .   ? -35.298 -12.415 0.757   1   44.92  ? 951 HOH B O   1 
HETATM 9185 O  O   . HOH Q 4 .   ? -23.212 -28.278 -6.835  1   50.02  ? 952 HOH B O   1 
HETATM 9186 O  O   . HOH Q 4 .   ? -24.084 -17.58  -9.57   1   54.98  ? 953 HOH B O   1 
HETATM 9187 O  O   . HOH Q 4 .   ? -24.218 -24.441 -4.251  1   43.46  ? 954 HOH B O   1 
HETATM 9188 O  O   . HOH Q 4 .   ? -7.055  -21.055 -10.501 1   46.92  ? 955 HOH B O   1 
HETATM 9189 O  O   . HOH Q 4 .   ? -32.911 -16.599 -3.562  1   40.59  ? 956 HOH B O   1 
HETATM 9190 O  O   . HOH Q 4 .   ? -31.354 -18.13  -18.71  1   49.57  ? 957 HOH B O   1 
HETATM 9191 O  O   . HOH Q 4 .   ? -29.56  -12.954 -20.978 1   56.29  ? 958 HOH B O   1 
HETATM 9192 O  O   . HOH Q 4 .   ? -25.664 -26.313 3.958   1   55.6   ? 959 HOH B O   1 
HETATM 9193 O  O   . HOH Q 4 .   ? -11.534 18.22   14.884  1   54.13  ? 960 HOH B O   1 
HETATM 9194 O  O   . HOH Q 4 .   ? -23.532 -26.372 -8.688  1   51.88  ? 961 HOH B O   1 
HETATM 9195 O  O   . HOH Q 4 .   ? -33.28  16.576  12.105  1   58.92  ? 962 HOH B O   1 
HETATM 9196 O  O   . HOH Q 4 .   ? -26.308 16.493  -8.505  1   52.53  ? 963 HOH B O   1 
HETATM 9197 O  O   . HOH Q 4 .   ? -27.77  -3.883  2.921   1   45.4   ? 964 HOH B O   1 
HETATM 9198 O  O   . HOH Q 4 .   ? -29.698 11.722  -2.772  1   44.6   ? 965 HOH B O   1 
HETATM 9199 O  O   . HOH Q 4 .   ? -33.075 17.034  8.565   1   60.08  ? 966 HOH B O   1 
HETATM 9200 O  O   . HOH Q 4 .   ? -23.862 20.106  0.347   1   53.33  ? 967 HOH B O   1 
HETATM 9201 O  O   . HOH Q 4 .   ? -35.516 -8.714  -1.695  1   42.99  ? 968 HOH B O   1 
HETATM 9202 O  O   . HOH Q 4 .   ? -6.288  -6.46   -2.13   1   44.72  ? 969 HOH B O   1 
HETATM 9203 O  O   . HOH Q 4 .   ? -23.418 8.689   -22.059 1   54.73  ? 970 HOH B O   1 
HETATM 9204 O  O   . HOH Q 4 .   ? -30.147 -21.178 -11.521 1   61.44  ? 971 HOH B O   1 
HETATM 9205 O  O   . HOH Q 4 .   ? -33.783 -12.957 2.81    1   35.99  ? 972 HOH B O   1 
HETATM 9206 O  O   . HOH Q 4 .   ? -30.032 8.879   12.974  1   51.15  ? 973 HOH B O   1 
HETATM 9207 O  O   . HOH Q 4 .   ? -1.905  -9.713  4.466   1   64.35  ? 974 HOH B O   1 
HETATM 9208 O  O   . HOH Q 4 .   ? -35.263 -3.955  -2.148  1   59.52  ? 975 HOH B O   1 
HETATM 9209 O  O   . HOH Q 4 .   ? -32.153 10.917  -11.888 1   50.18  ? 976 HOH B O   1 
HETATM 9210 O  O   . HOH Q 4 .   ? -29.736 13.458  -6.338  1   56.06  ? 977 HOH B O   1 
HETATM 9211 O  O   . HOH Q 4 .   ? -19.897 -5.738  -26.774 1   54.67  ? 978 HOH B O   1 
HETATM 9212 O  O   . HOH Q 4 .   ? -13.263 19.063  13.002  1   54.49  ? 979 HOH B O   1 
HETATM 9213 O  O   . HOH Q 4 .   ? -27.392 2.277   -1.149  1   49.55  ? 980 HOH B O   1 
HETATM 9214 O  O   . HOH Q 4 .   ? -25.785 3.834   18.442  1   52.08  ? 981 HOH B O   1 
HETATM 9215 O  O   . HOH Q 4 .   ? -24.798 9.859   -11.497 1   59.73  ? 982 HOH B O   1 
HETATM 9216 O  O   . HOH Q 4 .   ? -37.904 -9.698  -2.26   1   47.3   ? 983 HOH B O   1 
HETATM 9217 O  O   . HOH Q 4 .   ? -25.513 -0.169  -1.446  1   51.05  ? 984 HOH B O   1 
HETATM 9218 O  O   . HOH R 4 .   ? -44.471 24.259  17.091  1   62.44  ? 801 HOH C O   1 
HETATM 9219 O  O   . HOH R 4 .   ? -46.112 -5.527  29.227  1   48.05  ? 802 HOH C O   1 
HETATM 9220 O  O   . HOH R 4 .   ? -38.177 29      35.189  1   56.62  ? 803 HOH C O   1 
HETATM 9221 O  O   . HOH R 4 .   ? -35.549 13.613  33.576  1   53.69  ? 804 HOH C O   1 
HETATM 9222 O  O   . HOH R 4 .   ? -35.454 12.314  30.773  1   53.96  ? 805 HOH C O   1 
HETATM 9223 O  O   . HOH R 4 .   ? -24.411 0.245   48.17   1   54.86  ? 806 HOH C O   1 
HETATM 9224 O  O   . HOH R 4 .   ? -23.003 10.742  17.835  1   50.56  ? 807 HOH C O   1 
HETATM 9225 O  O   . HOH R 4 .   ? -15.062 12.375  30.046  1   61.11  ? 808 HOH C O   1 
HETATM 9226 O  O   . HOH R 4 .   ? -18.984 3.926   26.199  1   65.46  ? 809 HOH C O   1 
HETATM 9227 O  O   . HOH R 4 .   ? -54.209 1.635   39.098  1   63.45  ? 810 HOH C O   1 
HETATM 9228 O  O   . HOH R 4 .   ? -28.183 23.735  29.3    1   54.14  ? 811 HOH C O   1 
HETATM 9229 O  O   . HOH R 4 .   ? -39.787 2.218   41.345  1   54.99  ? 812 HOH C O   1 
HETATM 9230 O  O   . HOH R 4 .   ? -27.845 10.026  17.812  1   49.52  ? 813 HOH C O   1 
HETATM 9231 O  O   . HOH R 4 .   ? -42.149 0.987   42.657  1   53.62  ? 814 HOH C O   1 
HETATM 9232 O  O   . HOH R 4 .   ? -23.203 10.608  21.403  1   47.23  ? 815 HOH C O   1 
HETATM 9233 O  O   . HOH R 4 .   ? -52.385 23.067  38.147  1   55.53  ? 816 HOH C O   1 
HETATM 9234 O  O   . HOH R 4 .   ? -52.928 13.237  37.552  1   55.68  ? 817 HOH C O   1 
HETATM 9235 O  O   . HOH R 4 .   ? -37.928 11.51   19.811  1   54.06  ? 818 HOH C O   1 
HETATM 9236 O  O   . HOH R 4 .   ? -36.701 6.619   23.475  1   52.73  ? 819 HOH C O   1 
HETATM 9237 O  O   . HOH R 4 .   ? -54.712 18.507  39.793  1   58.85  ? 820 HOH C O   1 
HETATM 9238 O  O   . HOH R 4 .   ? -35.165 0.095   43.813  1   51.63  ? 821 HOH C O   1 
HETATM 9239 O  O   . HOH R 4 .   ? -40.434 11.464  36.72   1   55.97  ? 822 HOH C O   1 
HETATM 9240 O  O   . HOH R 4 .   ? -38.377 8.311   21.503  1   56.52  ? 823 HOH C O   1 
HETATM 9241 O  O   . HOH R 4 .   ? -54.253 24.154  53.268  1   58.74  ? 824 HOH C O   1 
HETATM 9242 O  O   . HOH R 4 .   ? -36.465 12.513  38.395  1   66.24  ? 825 HOH C O   1 
HETATM 9243 O  O   . HOH R 4 .   ? -42.451 9.179   34.963  1   41.24  ? 826 HOH C O   1 
HETATM 9244 O  O   . HOH R 4 .   ? -43.643 -1.195  35.097  1   50.42  ? 827 HOH C O   1 
HETATM 9245 O  O   . HOH R 4 .   ? -47.609 10.881  15.876  1   55.82  ? 828 HOH C O   1 
HETATM 9246 O  O   . HOH R 4 .   ? -49.295 12.562  34.738  1   54.09  ? 829 HOH C O   1 
HETATM 9247 O  O   . HOH R 4 .   ? -26.272 17.476  18.415  1   51.96  ? 830 HOH C O   1 
HETATM 9248 O  O   . HOH R 4 .   ? -38.766 -3.592  27.949  1   45.51  ? 831 HOH C O   1 
HETATM 9249 O  O   . HOH R 4 .   ? -14.209 5.297   20.946  1   52.67  ? 832 HOH C O   1 
HETATM 9250 O  O   . HOH R 4 .   ? -61.191 2.64    41.542  1   50.1   ? 833 HOH C O   1 
HETATM 9251 O  O   . HOH R 4 .   ? -60.093 5.356   37.741  1   60.27  ? 834 HOH C O   1 
HETATM 9252 O  O   . HOH R 4 .   ? -49.216 2.68    47.07   1   57.65  ? 835 HOH C O   1 
HETATM 9253 O  O   . HOH R 4 .   ? -26.127 8.328   19.523  1   47.33  ? 836 HOH C O   1 
HETATM 9254 O  O   . HOH R 4 .   ? -29.546 24.937  26.793  1   62.45  ? 837 HOH C O   1 
HETATM 9255 O  O   . HOH R 4 .   ? -21.512 0.057   28.247  1   66.76  ? 838 HOH C O   1 
HETATM 9256 O  O   . HOH R 4 .   ? -50.454 6.351   19.337  1   53.11  ? 839 HOH C O   1 
HETATM 9257 O  O   . HOH R 4 .   ? -22.934 0.579   25.198  1   57.28  ? 840 HOH C O   1 
HETATM 9258 O  O   . HOH R 4 .   ? -19.152 6.651   22.725  1   40.58  ? 841 HOH C O   1 
HETATM 9259 O  O   . HOH R 4 .   ? -34.254 18.31   36.272  1   58.06  ? 842 HOH C O   1 
HETATM 9260 O  O   . HOH R 4 .   ? -33.694 17.715  33.417  1   53.53  ? 843 HOH C O   1 
HETATM 9261 O  O   . HOH R 4 .   ? -24.571 8.457   21.913  1   44.56  ? 844 HOH C O   1 
HETATM 9262 O  O   . HOH R 4 .   ? -23.071 1.547   21.174  1   74.77  ? 845 HOH C O   1 
HETATM 9263 O  O   . HOH R 4 .   ? -37.037 8.584   18.319  1   61.09  ? 846 HOH C O   1 
# 
