data_9ET8
# 
_entry.id   9ET8 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ET8         pdb_00009et8 10.2210/pdb9et8/pdb 
WWPDB D_1292137034 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ET8 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Cyclin-A2                   30817.473 2   ?         ? ? ? 
2 polymer     man 'Cyclin-dependent kinase 2' 34354.770 2   2.7.11.22 ? ? ? 
3 non-polymer syn 4-iodanylpyridin-2-amine    220.011   6   ?         ? ? ? 
4 water       nat water                       18.015    284 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 Cyclin-A                                            
2 'Cell division protein kinase 2,p33 protein kinase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
D,B ? 
2 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 4-iodanylpyridin-2-amine IIS 
4 water                    HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   VAL n 
1 3   ASN n 
1 4   GLU n 
1 5   VAL n 
1 6   PRO n 
1 7   ASP n 
1 8   TYR n 
1 9   HIS n 
1 10  GLU n 
1 11  ASP n 
1 12  ILE n 
1 13  HIS n 
1 14  THR n 
1 15  TYR n 
1 16  LEU n 
1 17  ARG n 
1 18  GLU n 
1 19  MET n 
1 20  GLU n 
1 21  VAL n 
1 22  LYS n 
1 23  CYS n 
1 24  LYS n 
1 25  PRO n 
1 26  LYS n 
1 27  VAL n 
1 28  GLY n 
1 29  TYR n 
1 30  MET n 
1 31  LYS n 
1 32  LYS n 
1 33  GLN n 
1 34  PRO n 
1 35  ASP n 
1 36  ILE n 
1 37  THR n 
1 38  ASN n 
1 39  SER n 
1 40  MET n 
1 41  ARG n 
1 42  ALA n 
1 43  ILE n 
1 44  LEU n 
1 45  VAL n 
1 46  ASP n 
1 47  TRP n 
1 48  LEU n 
1 49  VAL n 
1 50  GLU n 
1 51  VAL n 
1 52  GLY n 
1 53  GLU n 
1 54  GLU n 
1 55  TYR n 
1 56  LYS n 
1 57  LEU n 
1 58  GLN n 
1 59  ASN n 
1 60  GLU n 
1 61  THR n 
1 62  LEU n 
1 63  HIS n 
1 64  LEU n 
1 65  ALA n 
1 66  VAL n 
1 67  ASN n 
1 68  TYR n 
1 69  ILE n 
1 70  ASP n 
1 71  ARG n 
1 72  PHE n 
1 73  LEU n 
1 74  SER n 
1 75  SER n 
1 76  MET n 
1 77  SER n 
1 78  VAL n 
1 79  LEU n 
1 80  ARG n 
1 81  GLY n 
1 82  LYS n 
1 83  LEU n 
1 84  GLN n 
1 85  LEU n 
1 86  VAL n 
1 87  GLY n 
1 88  THR n 
1 89  ALA n 
1 90  ALA n 
1 91  MET n 
1 92  LEU n 
1 93  LEU n 
1 94  ALA n 
1 95  SER n 
1 96  LYS n 
1 97  PHE n 
1 98  GLU n 
1 99  GLU n 
1 100 ILE n 
1 101 TYR n 
1 102 PRO n 
1 103 PRO n 
1 104 GLU n 
1 105 VAL n 
1 106 ALA n 
1 107 GLU n 
1 108 PHE n 
1 109 VAL n 
1 110 TYR n 
1 111 ILE n 
1 112 THR n 
1 113 ASP n 
1 114 ASP n 
1 115 THR n 
1 116 TYR n 
1 117 THR n 
1 118 LYS n 
1 119 LYS n 
1 120 GLN n 
1 121 VAL n 
1 122 LEU n 
1 123 ARG n 
1 124 MET n 
1 125 GLU n 
1 126 HIS n 
1 127 LEU n 
1 128 VAL n 
1 129 LEU n 
1 130 LYS n 
1 131 VAL n 
1 132 LEU n 
1 133 ALA n 
1 134 PHE n 
1 135 ASP n 
1 136 LEU n 
1 137 ALA n 
1 138 ALA n 
1 139 PRO n 
1 140 THR n 
1 141 ILE n 
1 142 ASN n 
1 143 GLN n 
1 144 PHE n 
1 145 LEU n 
1 146 THR n 
1 147 GLN n 
1 148 TYR n 
1 149 PHE n 
1 150 LEU n 
1 151 HIS n 
1 152 GLN n 
1 153 GLN n 
1 154 PRO n 
1 155 ALA n 
1 156 ASN n 
1 157 CYS n 
1 158 LYS n 
1 159 VAL n 
1 160 GLU n 
1 161 SER n 
1 162 LEU n 
1 163 ALA n 
1 164 MET n 
1 165 PHE n 
1 166 LEU n 
1 167 GLY n 
1 168 GLU n 
1 169 LEU n 
1 170 SER n 
1 171 LEU n 
1 172 ILE n 
1 173 ASP n 
1 174 ALA n 
1 175 ASP n 
1 176 PRO n 
1 177 TYR n 
1 178 LEU n 
1 179 LYS n 
1 180 TYR n 
1 181 LEU n 
1 182 PRO n 
1 183 SER n 
1 184 VAL n 
1 185 ILE n 
1 186 ALA n 
1 187 ALA n 
1 188 ALA n 
1 189 ALA n 
1 190 PHE n 
1 191 HIS n 
1 192 LEU n 
1 193 ALA n 
1 194 LEU n 
1 195 TYR n 
1 196 THR n 
1 197 VAL n 
1 198 THR n 
1 199 GLY n 
1 200 GLN n 
1 201 SER n 
1 202 TRP n 
1 203 PRO n 
1 204 GLU n 
1 205 SER n 
1 206 LEU n 
1 207 VAL n 
1 208 GLN n 
1 209 LYS n 
1 210 THR n 
1 211 GLY n 
1 212 TYR n 
1 213 THR n 
1 214 LEU n 
1 215 GLU n 
1 216 THR n 
1 217 LEU n 
1 218 LYS n 
1 219 PRO n 
1 220 CYS n 
1 221 LEU n 
1 222 LEU n 
1 223 ASP n 
1 224 LEU n 
1 225 HIS n 
1 226 GLN n 
1 227 THR n 
1 228 TYR n 
1 229 LEU n 
1 230 ARG n 
1 231 ALA n 
1 232 PRO n 
1 233 GLN n 
1 234 HIS n 
1 235 ALA n 
1 236 GLN n 
1 237 GLN n 
1 238 SER n 
1 239 ILE n 
1 240 ARG n 
1 241 GLU n 
1 242 LYS n 
1 243 TYR n 
1 244 LYS n 
1 245 ASN n 
1 246 SER n 
1 247 LYS n 
1 248 TYR n 
1 249 HIS n 
1 250 GLY n 
1 251 VAL n 
1 252 SER n 
1 253 LEU n 
1 254 LEU n 
1 255 ASN n 
1 256 PRO n 
1 257 PRO n 
1 258 GLU n 
1 259 THR n 
1 260 LEU n 
1 261 ASN n 
1 262 VAL n 
1 263 HIS n 
1 264 HIS n 
1 265 HIS n 
1 266 HIS n 
1 267 HIS n 
1 268 HIS n 
2 1   GLY n 
2 2   PRO n 
2 3   GLY n 
2 4   SER n 
2 5   MET n 
2 6   GLU n 
2 7   ASN n 
2 8   PHE n 
2 9   GLN n 
2 10  LYS n 
2 11  VAL n 
2 12  GLU n 
2 13  LYS n 
2 14  ILE n 
2 15  GLY n 
2 16  GLU n 
2 17  GLY n 
2 18  THR n 
2 19  TYR n 
2 20  GLY n 
2 21  VAL n 
2 22  VAL n 
2 23  TYR n 
2 24  LYS n 
2 25  ALA n 
2 26  ARG n 
2 27  ASN n 
2 28  LYS n 
2 29  LEU n 
2 30  THR n 
2 31  GLY n 
2 32  GLU n 
2 33  VAL n 
2 34  VAL n 
2 35  ALA n 
2 36  LEU n 
2 37  LYS n 
2 38  LYS n 
2 39  ILE n 
2 40  ARG n 
2 41  LEU n 
2 42  ASP n 
2 43  THR n 
2 44  GLU n 
2 45  THR n 
2 46  GLU n 
2 47  GLY n 
2 48  VAL n 
2 49  PRO n 
2 50  SER n 
2 51  THR n 
2 52  ALA n 
2 53  ILE n 
2 54  ARG n 
2 55  GLU n 
2 56  ILE n 
2 57  SER n 
2 58  LEU n 
2 59  LEU n 
2 60  LYS n 
2 61  GLU n 
2 62  LEU n 
2 63  ASN n 
2 64  HIS n 
2 65  PRO n 
2 66  ASN n 
2 67  ILE n 
2 68  VAL n 
2 69  LYS n 
2 70  LEU n 
2 71  LEU n 
2 72  ASP n 
2 73  VAL n 
2 74  ILE n 
2 75  HIS n 
2 76  THR n 
2 77  GLU n 
2 78  ASN n 
2 79  LYS n 
2 80  LEU n 
2 81  TYR n 
2 82  LEU n 
2 83  VAL n 
2 84  PHE n 
2 85  GLU n 
2 86  PHE n 
2 87  LEU n 
2 88  HIS n 
2 89  GLN n 
2 90  ASP n 
2 91  LEU n 
2 92  LYS n 
2 93  LYS n 
2 94  PHE n 
2 95  MET n 
2 96  ASP n 
2 97  ALA n 
2 98  SER n 
2 99  ALA n 
2 100 LEU n 
2 101 THR n 
2 102 GLY n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 PRO n 
2 107 LEU n 
2 108 ILE n 
2 109 LYS n 
2 110 SER n 
2 111 TYR n 
2 112 LEU n 
2 113 PHE n 
2 114 GLN n 
2 115 LEU n 
2 116 LEU n 
2 117 GLN n 
2 118 GLY n 
2 119 LEU n 
2 120 ALA n 
2 121 PHE n 
2 122 CYS n 
2 123 HIS n 
2 124 SER n 
2 125 HIS n 
2 126 ARG n 
2 127 VAL n 
2 128 LEU n 
2 129 HIS n 
2 130 ARG n 
2 131 ASP n 
2 132 LEU n 
2 133 LYS n 
2 134 PRO n 
2 135 GLN n 
2 136 ASN n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ASN n 
2 141 THR n 
2 142 GLU n 
2 143 GLY n 
2 144 ALA n 
2 145 ILE n 
2 146 LYS n 
2 147 LEU n 
2 148 ALA n 
2 149 ASP n 
2 150 PHE n 
2 151 GLY n 
2 152 LEU n 
2 153 ALA n 
2 154 ARG n 
2 155 ALA n 
2 156 PHE n 
2 157 GLY n 
2 158 VAL n 
2 159 PRO n 
2 160 VAL n 
2 161 ARG n 
2 162 THR n 
2 163 TYR n 
2 164 TPO n 
2 165 HIS n 
2 166 GLU n 
2 167 VAL n 
2 168 VAL n 
2 169 THR n 
2 170 LEU n 
2 171 TRP n 
2 172 TYR n 
2 173 ARG n 
2 174 ALA n 
2 175 PRO n 
2 176 GLU n 
2 177 ILE n 
2 178 LEU n 
2 179 LEU n 
2 180 GLY n 
2 181 CYS n 
2 182 LYS n 
2 183 TYR n 
2 184 TYR n 
2 185 SER n 
2 186 THR n 
2 187 ALA n 
2 188 VAL n 
2 189 ASP n 
2 190 ILE n 
2 191 TRP n 
2 192 SER n 
2 193 LEU n 
2 194 GLY n 
2 195 CYS n 
2 196 ILE n 
2 197 PHE n 
2 198 ALA n 
2 199 GLU n 
2 200 MET n 
2 201 VAL n 
2 202 THR n 
2 203 ARG n 
2 204 ARG n 
2 205 ALA n 
2 206 LEU n 
2 207 PHE n 
2 208 PRO n 
2 209 GLY n 
2 210 ASP n 
2 211 SER n 
2 212 GLU n 
2 213 ILE n 
2 214 ASP n 
2 215 GLN n 
2 216 LEU n 
2 217 PHE n 
2 218 ARG n 
2 219 ILE n 
2 220 PHE n 
2 221 ARG n 
2 222 THR n 
2 223 LEU n 
2 224 GLY n 
2 225 THR n 
2 226 PRO n 
2 227 ASP n 
2 228 GLU n 
2 229 VAL n 
2 230 VAL n 
2 231 TRP n 
2 232 PRO n 
2 233 GLY n 
2 234 VAL n 
2 235 THR n 
2 236 SER n 
2 237 MET n 
2 238 PRO n 
2 239 ASP n 
2 240 TYR n 
2 241 LYS n 
2 242 PRO n 
2 243 SER n 
2 244 PHE n 
2 245 PRO n 
2 246 LYS n 
2 247 TRP n 
2 248 ALA n 
2 249 ARG n 
2 250 GLN n 
2 251 ASP n 
2 252 PHE n 
2 253 SER n 
2 254 LYS n 
2 255 VAL n 
2 256 VAL n 
2 257 PRO n 
2 258 PRO n 
2 259 LEU n 
2 260 ASP n 
2 261 GLU n 
2 262 ASP n 
2 263 GLY n 
2 264 ARG n 
2 265 SER n 
2 266 LEU n 
2 267 LEU n 
2 268 SER n 
2 269 GLN n 
2 270 MET n 
2 271 LEU n 
2 272 HIS n 
2 273 TYR n 
2 274 ASP n 
2 275 PRO n 
2 276 ASN n 
2 277 LYS n 
2 278 ARG n 
2 279 ILE n 
2 280 SER n 
2 281 ALA n 
2 282 LYS n 
2 283 ALA n 
2 284 ALA n 
2 285 LEU n 
2 286 ALA n 
2 287 HIS n 
2 288 PRO n 
2 289 PHE n 
2 290 PHE n 
2 291 GLN n 
2 292 ASP n 
2 293 VAL n 
2 294 THR n 
2 295 LYS n 
2 296 PRO n 
2 297 VAL n 
2 298 PRO n 
2 299 HIS n 
2 300 LEU n 
2 301 ARG n 
2 302 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
2 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                  ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                 ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE               ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'          ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                 ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'          ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                  ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                    ?                  'H2 O'           18.015  
IIS non-polymer         . 4-iodanylpyridin-2-amine ?                  'C5 H5 I N2'     220.011 
ILE 'L-peptide linking' y ISOLEUCINE               ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                  ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                   ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE               ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE            ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                  ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                   ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE         PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN               ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                 ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                   ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   171 171 GLY GLY D . n 
A 1 2   VAL 2   172 172 VAL VAL D . n 
A 1 3   ASN 3   173 173 ASN ASN D . n 
A 1 4   GLU 4   174 174 GLU GLU D . n 
A 1 5   VAL 5   175 175 VAL VAL D . n 
A 1 6   PRO 6   176 176 PRO PRO D . n 
A 1 7   ASP 7   177 177 ASP ASP D . n 
A 1 8   TYR 8   178 178 TYR TYR D . n 
A 1 9   HIS 9   179 179 HIS HIS D . n 
A 1 10  GLU 10  180 180 GLU GLU D . n 
A 1 11  ASP 11  181 181 ASP ASP D . n 
A 1 12  ILE 12  182 182 ILE ILE D . n 
A 1 13  HIS 13  183 183 HIS HIS D . n 
A 1 14  THR 14  184 184 THR THR D . n 
A 1 15  TYR 15  185 185 TYR TYR D . n 
A 1 16  LEU 16  186 186 LEU LEU D . n 
A 1 17  ARG 17  187 187 ARG ARG D . n 
A 1 18  GLU 18  188 188 GLU GLU D . n 
A 1 19  MET 19  189 189 MET MET D . n 
A 1 20  GLU 20  190 190 GLU GLU D . n 
A 1 21  VAL 21  191 191 VAL VAL D . n 
A 1 22  LYS 22  192 192 LYS LYS D . n 
A 1 23  CYS 23  193 193 CYS CYS D . n 
A 1 24  LYS 24  194 194 LYS LYS D . n 
A 1 25  PRO 25  195 195 PRO PRO D . n 
A 1 26  LYS 26  196 196 LYS LYS D . n 
A 1 27  VAL 27  197 197 VAL VAL D . n 
A 1 28  GLY 28  198 198 GLY GLY D . n 
A 1 29  TYR 29  199 199 TYR TYR D . n 
A 1 30  MET 30  200 200 MET MET D . n 
A 1 31  LYS 31  201 201 LYS LYS D . n 
A 1 32  LYS 32  202 202 LYS LYS D . n 
A 1 33  GLN 33  203 203 GLN GLN D . n 
A 1 34  PRO 34  204 204 PRO PRO D . n 
A 1 35  ASP 35  205 205 ASP ASP D . n 
A 1 36  ILE 36  206 206 ILE ILE D . n 
A 1 37  THR 37  207 207 THR THR D . n 
A 1 38  ASN 38  208 208 ASN ASN D . n 
A 1 39  SER 39  209 209 SER SER D . n 
A 1 40  MET 40  210 210 MET MET D . n 
A 1 41  ARG 41  211 211 ARG ARG D . n 
A 1 42  ALA 42  212 212 ALA ALA D . n 
A 1 43  ILE 43  213 213 ILE ILE D . n 
A 1 44  LEU 44  214 214 LEU LEU D . n 
A 1 45  VAL 45  215 215 VAL VAL D . n 
A 1 46  ASP 46  216 216 ASP ASP D . n 
A 1 47  TRP 47  217 217 TRP TRP D . n 
A 1 48  LEU 48  218 218 LEU LEU D . n 
A 1 49  VAL 49  219 219 VAL VAL D . n 
A 1 50  GLU 50  220 220 GLU GLU D . n 
A 1 51  VAL 51  221 221 VAL VAL D . n 
A 1 52  GLY 52  222 222 GLY GLY D . n 
A 1 53  GLU 53  223 223 GLU GLU D . n 
A 1 54  GLU 54  224 224 GLU GLU D . n 
A 1 55  TYR 55  225 225 TYR TYR D . n 
A 1 56  LYS 56  226 226 LYS LYS D . n 
A 1 57  LEU 57  227 227 LEU LEU D . n 
A 1 58  GLN 58  228 228 GLN GLN D . n 
A 1 59  ASN 59  229 229 ASN ASN D . n 
A 1 60  GLU 60  230 230 GLU GLU D . n 
A 1 61  THR 61  231 231 THR THR D . n 
A 1 62  LEU 62  232 232 LEU LEU D . n 
A 1 63  HIS 63  233 233 HIS HIS D . n 
A 1 64  LEU 64  234 234 LEU LEU D . n 
A 1 65  ALA 65  235 235 ALA ALA D . n 
A 1 66  VAL 66  236 236 VAL VAL D . n 
A 1 67  ASN 67  237 237 ASN ASN D . n 
A 1 68  TYR 68  238 238 TYR TYR D . n 
A 1 69  ILE 69  239 239 ILE ILE D . n 
A 1 70  ASP 70  240 240 ASP ASP D . n 
A 1 71  ARG 71  241 241 ARG ARG D . n 
A 1 72  PHE 72  242 242 PHE PHE D . n 
A 1 73  LEU 73  243 243 LEU LEU D . n 
A 1 74  SER 74  244 244 SER SER D . n 
A 1 75  SER 75  245 245 SER SER D . n 
A 1 76  MET 76  246 246 MET MET D . n 
A 1 77  SER 77  247 247 SER SER D . n 
A 1 78  VAL 78  248 248 VAL VAL D . n 
A 1 79  LEU 79  249 249 LEU LEU D . n 
A 1 80  ARG 80  250 250 ARG ARG D . n 
A 1 81  GLY 81  251 251 GLY GLY D . n 
A 1 82  LYS 82  252 252 LYS LYS D . n 
A 1 83  LEU 83  253 253 LEU LEU D . n 
A 1 84  GLN 84  254 254 GLN GLN D . n 
A 1 85  LEU 85  255 255 LEU LEU D . n 
A 1 86  VAL 86  256 256 VAL VAL D . n 
A 1 87  GLY 87  257 257 GLY GLY D . n 
A 1 88  THR 88  258 258 THR THR D . n 
A 1 89  ALA 89  259 259 ALA ALA D . n 
A 1 90  ALA 90  260 260 ALA ALA D . n 
A 1 91  MET 91  261 261 MET MET D . n 
A 1 92  LEU 92  262 262 LEU LEU D . n 
A 1 93  LEU 93  263 263 LEU LEU D . n 
A 1 94  ALA 94  264 264 ALA ALA D . n 
A 1 95  SER 95  265 265 SER SER D . n 
A 1 96  LYS 96  266 266 LYS LYS D . n 
A 1 97  PHE 97  267 267 PHE PHE D . n 
A 1 98  GLU 98  268 268 GLU GLU D . n 
A 1 99  GLU 99  269 269 GLU GLU D . n 
A 1 100 ILE 100 270 270 ILE ILE D . n 
A 1 101 TYR 101 271 271 TYR TYR D . n 
A 1 102 PRO 102 272 272 PRO PRO D . n 
A 1 103 PRO 103 273 273 PRO PRO D . n 
A 1 104 GLU 104 274 274 GLU GLU D . n 
A 1 105 VAL 105 275 275 VAL VAL D . n 
A 1 106 ALA 106 276 276 ALA ALA D . n 
A 1 107 GLU 107 277 277 GLU GLU D . n 
A 1 108 PHE 108 278 278 PHE PHE D . n 
A 1 109 VAL 109 279 279 VAL VAL D . n 
A 1 110 TYR 110 280 280 TYR TYR D . n 
A 1 111 ILE 111 281 281 ILE ILE D . n 
A 1 112 THR 112 282 282 THR THR D . n 
A 1 113 ASP 113 283 283 ASP ASP D . n 
A 1 114 ASP 114 284 284 ASP ASP D . n 
A 1 115 THR 115 285 285 THR THR D . n 
A 1 116 TYR 116 286 286 TYR TYR D . n 
A 1 117 THR 117 287 287 THR THR D . n 
A 1 118 LYS 118 288 288 LYS LYS D . n 
A 1 119 LYS 119 289 289 LYS LYS D . n 
A 1 120 GLN 120 290 290 GLN GLN D . n 
A 1 121 VAL 121 291 291 VAL VAL D . n 
A 1 122 LEU 122 292 292 LEU LEU D . n 
A 1 123 ARG 123 293 293 ARG ARG D . n 
A 1 124 MET 124 294 294 MET MET D . n 
A 1 125 GLU 125 295 295 GLU GLU D . n 
A 1 126 HIS 126 296 296 HIS HIS D . n 
A 1 127 LEU 127 297 297 LEU LEU D . n 
A 1 128 VAL 128 298 298 VAL VAL D . n 
A 1 129 LEU 129 299 299 LEU LEU D . n 
A 1 130 LYS 130 300 300 LYS LYS D . n 
A 1 131 VAL 131 301 301 VAL VAL D . n 
A 1 132 LEU 132 302 302 LEU LEU D . n 
A 1 133 ALA 133 303 303 ALA ALA D . n 
A 1 134 PHE 134 304 304 PHE PHE D . n 
A 1 135 ASP 135 305 305 ASP ASP D . n 
A 1 136 LEU 136 306 306 LEU LEU D . n 
A 1 137 ALA 137 307 307 ALA ALA D . n 
A 1 138 ALA 138 308 308 ALA ALA D . n 
A 1 139 PRO 139 309 309 PRO PRO D . n 
A 1 140 THR 140 310 310 THR THR D . n 
A 1 141 ILE 141 311 311 ILE ILE D . n 
A 1 142 ASN 142 312 312 ASN ASN D . n 
A 1 143 GLN 143 313 313 GLN GLN D . n 
A 1 144 PHE 144 314 314 PHE PHE D . n 
A 1 145 LEU 145 315 315 LEU LEU D . n 
A 1 146 THR 146 316 316 THR THR D . n 
A 1 147 GLN 147 317 317 GLN GLN D . n 
A 1 148 TYR 148 318 318 TYR TYR D . n 
A 1 149 PHE 149 319 319 PHE PHE D . n 
A 1 150 LEU 150 320 320 LEU LEU D . n 
A 1 151 HIS 151 321 321 HIS HIS D . n 
A 1 152 GLN 152 322 322 GLN GLN D . n 
A 1 153 GLN 153 323 323 GLN GLN D . n 
A 1 154 PRO 154 324 324 PRO PRO D . n 
A 1 155 ALA 155 325 325 ALA ALA D . n 
A 1 156 ASN 156 326 326 ASN ASN D . n 
A 1 157 CYS 157 327 327 CYS CYS D . n 
A 1 158 LYS 158 328 328 LYS LYS D . n 
A 1 159 VAL 159 329 329 VAL VAL D . n 
A 1 160 GLU 160 330 330 GLU GLU D . n 
A 1 161 SER 161 331 331 SER SER D . n 
A 1 162 LEU 162 332 332 LEU LEU D . n 
A 1 163 ALA 163 333 333 ALA ALA D . n 
A 1 164 MET 164 334 334 MET MET D . n 
A 1 165 PHE 165 335 335 PHE PHE D . n 
A 1 166 LEU 166 336 336 LEU LEU D . n 
A 1 167 GLY 167 337 337 GLY GLY D . n 
A 1 168 GLU 168 338 338 GLU GLU D . n 
A 1 169 LEU 169 339 339 LEU LEU D . n 
A 1 170 SER 170 340 340 SER SER D . n 
A 1 171 LEU 171 341 341 LEU LEU D . n 
A 1 172 ILE 172 342 342 ILE ILE D . n 
A 1 173 ASP 173 343 343 ASP ASP D . n 
A 1 174 ALA 174 344 344 ALA ALA D . n 
A 1 175 ASP 175 345 345 ASP ASP D . n 
A 1 176 PRO 176 346 346 PRO PRO D . n 
A 1 177 TYR 177 347 347 TYR TYR D . n 
A 1 178 LEU 178 348 348 LEU LEU D . n 
A 1 179 LYS 179 349 349 LYS LYS D . n 
A 1 180 TYR 180 350 350 TYR TYR D . n 
A 1 181 LEU 181 351 351 LEU LEU D . n 
A 1 182 PRO 182 352 352 PRO PRO D . n 
A 1 183 SER 183 353 353 SER SER D . n 
A 1 184 VAL 184 354 354 VAL VAL D . n 
A 1 185 ILE 185 355 355 ILE ILE D . n 
A 1 186 ALA 186 356 356 ALA ALA D . n 
A 1 187 ALA 187 357 357 ALA ALA D . n 
A 1 188 ALA 188 358 358 ALA ALA D . n 
A 1 189 ALA 189 359 359 ALA ALA D . n 
A 1 190 PHE 190 360 360 PHE PHE D . n 
A 1 191 HIS 191 361 361 HIS HIS D . n 
A 1 192 LEU 192 362 362 LEU LEU D . n 
A 1 193 ALA 193 363 363 ALA ALA D . n 
A 1 194 LEU 194 364 364 LEU LEU D . n 
A 1 195 TYR 195 365 365 TYR TYR D . n 
A 1 196 THR 196 366 366 THR THR D . n 
A 1 197 VAL 197 367 367 VAL VAL D . n 
A 1 198 THR 198 368 368 THR THR D . n 
A 1 199 GLY 199 369 369 GLY GLY D . n 
A 1 200 GLN 200 370 370 GLN GLN D . n 
A 1 201 SER 201 371 371 SER SER D . n 
A 1 202 TRP 202 372 372 TRP TRP D . n 
A 1 203 PRO 203 373 373 PRO PRO D . n 
A 1 204 GLU 204 374 374 GLU GLU D . n 
A 1 205 SER 205 375 375 SER SER D . n 
A 1 206 LEU 206 376 376 LEU LEU D . n 
A 1 207 VAL 207 377 377 VAL VAL D . n 
A 1 208 GLN 208 378 378 GLN GLN D . n 
A 1 209 LYS 209 379 379 LYS LYS D . n 
A 1 210 THR 210 380 380 THR THR D . n 
A 1 211 GLY 211 381 381 GLY GLY D . n 
A 1 212 TYR 212 382 382 TYR TYR D . n 
A 1 213 THR 213 383 383 THR THR D . n 
A 1 214 LEU 214 384 384 LEU LEU D . n 
A 1 215 GLU 215 385 385 GLU GLU D . n 
A 1 216 THR 216 386 386 THR THR D . n 
A 1 217 LEU 217 387 387 LEU LEU D . n 
A 1 218 LYS 218 388 388 LYS LYS D . n 
A 1 219 PRO 219 389 389 PRO PRO D . n 
A 1 220 CYS 220 390 390 CYS CYS D . n 
A 1 221 LEU 221 391 391 LEU LEU D . n 
A 1 222 LEU 222 392 392 LEU LEU D . n 
A 1 223 ASP 223 393 393 ASP ASP D . n 
A 1 224 LEU 224 394 394 LEU LEU D . n 
A 1 225 HIS 225 395 395 HIS HIS D . n 
A 1 226 GLN 226 396 396 GLN GLN D . n 
A 1 227 THR 227 397 397 THR THR D . n 
A 1 228 TYR 228 398 398 TYR TYR D . n 
A 1 229 LEU 229 399 399 LEU LEU D . n 
A 1 230 ARG 230 400 400 ARG ARG D . n 
A 1 231 ALA 231 401 401 ALA ALA D . n 
A 1 232 PRO 232 402 402 PRO PRO D . n 
A 1 233 GLN 233 403 403 GLN GLN D . n 
A 1 234 HIS 234 404 404 HIS HIS D . n 
A 1 235 ALA 235 405 405 ALA ALA D . n 
A 1 236 GLN 236 406 406 GLN GLN D . n 
A 1 237 GLN 237 407 407 GLN GLN D . n 
A 1 238 SER 238 408 408 SER SER D . n 
A 1 239 ILE 239 409 409 ILE ILE D . n 
A 1 240 ARG 240 410 410 ARG ARG D . n 
A 1 241 GLU 241 411 411 GLU GLU D . n 
A 1 242 LYS 242 412 412 LYS LYS D . n 
A 1 243 TYR 243 413 413 TYR TYR D . n 
A 1 244 LYS 244 414 414 LYS LYS D . n 
A 1 245 ASN 245 415 415 ASN ASN D . n 
A 1 246 SER 246 416 416 SER SER D . n 
A 1 247 LYS 247 417 417 LYS LYS D . n 
A 1 248 TYR 248 418 418 TYR TYR D . n 
A 1 249 HIS 249 419 419 HIS HIS D . n 
A 1 250 GLY 250 420 420 GLY GLY D . n 
A 1 251 VAL 251 421 421 VAL VAL D . n 
A 1 252 SER 252 422 422 SER SER D . n 
A 1 253 LEU 253 423 423 LEU LEU D . n 
A 1 254 LEU 254 424 424 LEU LEU D . n 
A 1 255 ASN 255 425 425 ASN ASN D . n 
A 1 256 PRO 256 426 426 PRO PRO D . n 
A 1 257 PRO 257 427 427 PRO PRO D . n 
A 1 258 GLU 258 428 428 GLU GLU D . n 
A 1 259 THR 259 429 429 THR THR D . n 
A 1 260 LEU 260 430 430 LEU LEU D . n 
A 1 261 ASN 261 431 431 ASN ASN D . n 
A 1 262 VAL 262 432 432 VAL VAL D . n 
A 1 263 HIS 263 433 ?   ?   ?   D . n 
A 1 264 HIS 264 434 ?   ?   ?   D . n 
A 1 265 HIS 265 435 ?   ?   ?   D . n 
A 1 266 HIS 266 436 ?   ?   ?   D . n 
A 1 267 HIS 267 437 ?   ?   ?   D . n 
A 1 268 HIS 268 438 ?   ?   ?   D . n 
B 2 1   GLY 1   -3  -3  GLY GLY A . n 
B 2 2   PRO 2   -2  -2  PRO PRO A . n 
B 2 3   GLY 3   -1  -1  GLY GLY A . n 
B 2 4   SER 4   0   0   SER SER A . n 
B 2 5   MET 5   1   1   MET MET A . n 
B 2 6   GLU 6   2   2   GLU GLU A . n 
B 2 7   ASN 7   3   3   ASN ASN A . n 
B 2 8   PHE 8   4   4   PHE PHE A . n 
B 2 9   GLN 9   5   5   GLN GLN A . n 
B 2 10  LYS 10  6   6   LYS LYS A . n 
B 2 11  VAL 11  7   7   VAL VAL A . n 
B 2 12  GLU 12  8   8   GLU GLU A . n 
B 2 13  LYS 13  9   9   LYS LYS A . n 
B 2 14  ILE 14  10  10  ILE ILE A . n 
B 2 15  GLY 15  11  11  GLY GLY A . n 
B 2 16  GLU 16  12  12  GLU GLU A . n 
B 2 17  GLY 17  13  13  GLY GLY A . n 
B 2 18  THR 18  14  14  THR THR A . n 
B 2 19  TYR 19  15  15  TYR TYR A . n 
B 2 20  GLY 20  16  16  GLY GLY A . n 
B 2 21  VAL 21  17  17  VAL VAL A . n 
B 2 22  VAL 22  18  18  VAL VAL A . n 
B 2 23  TYR 23  19  19  TYR TYR A . n 
B 2 24  LYS 24  20  20  LYS LYS A . n 
B 2 25  ALA 25  21  21  ALA ALA A . n 
B 2 26  ARG 26  22  22  ARG ARG A . n 
B 2 27  ASN 27  23  23  ASN ASN A . n 
B 2 28  LYS 28  24  24  LYS LYS A . n 
B 2 29  LEU 29  25  25  LEU LEU A . n 
B 2 30  THR 30  26  26  THR THR A . n 
B 2 31  GLY 31  27  27  GLY GLY A . n 
B 2 32  GLU 32  28  28  GLU GLU A . n 
B 2 33  VAL 33  29  29  VAL VAL A . n 
B 2 34  VAL 34  30  30  VAL VAL A . n 
B 2 35  ALA 35  31  31  ALA ALA A . n 
B 2 36  LEU 36  32  32  LEU LEU A . n 
B 2 37  LYS 37  33  33  LYS LYS A . n 
B 2 38  LYS 38  34  34  LYS LYS A . n 
B 2 39  ILE 39  35  35  ILE ILE A . n 
B 2 40  ARG 40  36  36  ARG ARG A . n 
B 2 41  LEU 41  37  37  LEU LEU A . n 
B 2 42  ASP 42  38  38  ASP ASP A . n 
B 2 43  THR 43  39  39  THR THR A . n 
B 2 44  GLU 44  40  40  GLU GLU A . n 
B 2 45  THR 45  41  41  THR THR A . n 
B 2 46  GLU 46  42  42  GLU GLU A . n 
B 2 47  GLY 47  43  43  GLY GLY A . n 
B 2 48  VAL 48  44  44  VAL VAL A . n 
B 2 49  PRO 49  45  45  PRO PRO A . n 
B 2 50  SER 50  46  46  SER SER A . n 
B 2 51  THR 51  47  47  THR THR A . n 
B 2 52  ALA 52  48  48  ALA ALA A . n 
B 2 53  ILE 53  49  49  ILE ILE A . n 
B 2 54  ARG 54  50  50  ARG ARG A . n 
B 2 55  GLU 55  51  51  GLU GLU A . n 
B 2 56  ILE 56  52  52  ILE ILE A . n 
B 2 57  SER 57  53  53  SER SER A . n 
B 2 58  LEU 58  54  54  LEU LEU A . n 
B 2 59  LEU 59  55  55  LEU LEU A . n 
B 2 60  LYS 60  56  56  LYS LYS A . n 
B 2 61  GLU 61  57  57  GLU GLU A . n 
B 2 62  LEU 62  58  58  LEU LEU A . n 
B 2 63  ASN 63  59  59  ASN ASN A . n 
B 2 64  HIS 64  60  60  HIS HIS A . n 
B 2 65  PRO 65  61  61  PRO PRO A . n 
B 2 66  ASN 66  62  62  ASN ASN A . n 
B 2 67  ILE 67  63  63  ILE ILE A . n 
B 2 68  VAL 68  64  64  VAL VAL A . n 
B 2 69  LYS 69  65  65  LYS LYS A . n 
B 2 70  LEU 70  66  66  LEU LEU A . n 
B 2 71  LEU 71  67  67  LEU LEU A . n 
B 2 72  ASP 72  68  68  ASP ASP A . n 
B 2 73  VAL 73  69  69  VAL VAL A . n 
B 2 74  ILE 74  70  70  ILE ILE A . n 
B 2 75  HIS 75  71  71  HIS HIS A . n 
B 2 76  THR 76  72  72  THR THR A . n 
B 2 77  GLU 77  73  73  GLU GLU A . n 
B 2 78  ASN 78  74  74  ASN ASN A . n 
B 2 79  LYS 79  75  75  LYS LYS A . n 
B 2 80  LEU 80  76  76  LEU LEU A . n 
B 2 81  TYR 81  77  77  TYR TYR A . n 
B 2 82  LEU 82  78  78  LEU LEU A . n 
B 2 83  VAL 83  79  79  VAL VAL A . n 
B 2 84  PHE 84  80  80  PHE PHE A . n 
B 2 85  GLU 85  81  81  GLU GLU A . n 
B 2 86  PHE 86  82  82  PHE PHE A . n 
B 2 87  LEU 87  83  83  LEU LEU A . n 
B 2 88  HIS 88  84  84  HIS HIS A . n 
B 2 89  GLN 89  85  85  GLN GLN A . n 
B 2 90  ASP 90  86  86  ASP ASP A . n 
B 2 91  LEU 91  87  87  LEU LEU A . n 
B 2 92  LYS 92  88  88  LYS LYS A . n 
B 2 93  LYS 93  89  89  LYS LYS A . n 
B 2 94  PHE 94  90  90  PHE PHE A . n 
B 2 95  MET 95  91  91  MET MET A . n 
B 2 96  ASP 96  92  92  ASP ASP A . n 
B 2 97  ALA 97  93  93  ALA ALA A . n 
B 2 98  SER 98  94  94  SER SER A . n 
B 2 99  ALA 99  95  95  ALA ALA A . n 
B 2 100 LEU 100 96  96  LEU LEU A . n 
B 2 101 THR 101 97  97  THR THR A . n 
B 2 102 GLY 102 98  98  GLY GLY A . n 
B 2 103 ILE 103 99  99  ILE ILE A . n 
B 2 104 PRO 104 100 100 PRO PRO A . n 
B 2 105 LEU 105 101 101 LEU LEU A . n 
B 2 106 PRO 106 102 102 PRO PRO A . n 
B 2 107 LEU 107 103 103 LEU LEU A . n 
B 2 108 ILE 108 104 104 ILE ILE A . n 
B 2 109 LYS 109 105 105 LYS LYS A . n 
B 2 110 SER 110 106 106 SER SER A . n 
B 2 111 TYR 111 107 107 TYR TYR A . n 
B 2 112 LEU 112 108 108 LEU LEU A . n 
B 2 113 PHE 113 109 109 PHE PHE A . n 
B 2 114 GLN 114 110 110 GLN GLN A . n 
B 2 115 LEU 115 111 111 LEU LEU A . n 
B 2 116 LEU 116 112 112 LEU LEU A . n 
B 2 117 GLN 117 113 113 GLN GLN A . n 
B 2 118 GLY 118 114 114 GLY GLY A . n 
B 2 119 LEU 119 115 115 LEU LEU A . n 
B 2 120 ALA 120 116 116 ALA ALA A . n 
B 2 121 PHE 121 117 117 PHE PHE A . n 
B 2 122 CYS 122 118 118 CYS CYS A . n 
B 2 123 HIS 123 119 119 HIS HIS A . n 
B 2 124 SER 124 120 120 SER SER A . n 
B 2 125 HIS 125 121 121 HIS HIS A . n 
B 2 126 ARG 126 122 122 ARG ARG A . n 
B 2 127 VAL 127 123 123 VAL VAL A . n 
B 2 128 LEU 128 124 124 LEU LEU A . n 
B 2 129 HIS 129 125 125 HIS HIS A . n 
B 2 130 ARG 130 126 126 ARG ARG A . n 
B 2 131 ASP 131 127 127 ASP ASP A . n 
B 2 132 LEU 132 128 128 LEU LEU A . n 
B 2 133 LYS 133 129 129 LYS LYS A . n 
B 2 134 PRO 134 130 130 PRO PRO A . n 
B 2 135 GLN 135 131 131 GLN GLN A . n 
B 2 136 ASN 136 132 132 ASN ASN A . n 
B 2 137 LEU 137 133 133 LEU LEU A . n 
B 2 138 LEU 138 134 134 LEU LEU A . n 
B 2 139 ILE 139 135 135 ILE ILE A . n 
B 2 140 ASN 140 136 136 ASN ASN A . n 
B 2 141 THR 141 137 137 THR THR A . n 
B 2 142 GLU 142 138 138 GLU GLU A . n 
B 2 143 GLY 143 139 139 GLY GLY A . n 
B 2 144 ALA 144 140 140 ALA ALA A . n 
B 2 145 ILE 145 141 141 ILE ILE A . n 
B 2 146 LYS 146 142 142 LYS LYS A . n 
B 2 147 LEU 147 143 143 LEU LEU A . n 
B 2 148 ALA 148 144 144 ALA ALA A . n 
B 2 149 ASP 149 145 145 ASP ASP A . n 
B 2 150 PHE 150 146 146 PHE PHE A . n 
B 2 151 GLY 151 147 147 GLY GLY A . n 
B 2 152 LEU 152 148 148 LEU LEU A . n 
B 2 153 ALA 153 149 149 ALA ALA A . n 
B 2 154 ARG 154 150 150 ARG ARG A . n 
B 2 155 ALA 155 151 151 ALA ALA A . n 
B 2 156 PHE 156 152 152 PHE PHE A . n 
B 2 157 GLY 157 153 153 GLY GLY A . n 
B 2 158 VAL 158 154 154 VAL VAL A . n 
B 2 159 PRO 159 155 155 PRO PRO A . n 
B 2 160 VAL 160 156 156 VAL VAL A . n 
B 2 161 ARG 161 157 157 ARG ARG A . n 
B 2 162 THR 162 158 158 THR THR A . n 
B 2 163 TYR 163 159 159 TYR TYR A . n 
B 2 164 TPO 164 160 160 TPO TPO A . n 
B 2 165 HIS 165 161 161 HIS HIS A . n 
B 2 166 GLU 166 162 162 GLU GLU A . n 
B 2 167 VAL 167 163 163 VAL VAL A . n 
B 2 168 VAL 168 164 164 VAL VAL A . n 
B 2 169 THR 169 165 165 THR THR A . n 
B 2 170 LEU 170 166 166 LEU LEU A . n 
B 2 171 TRP 171 167 167 TRP TRP A . n 
B 2 172 TYR 172 168 168 TYR TYR A . n 
B 2 173 ARG 173 169 169 ARG ARG A . n 
B 2 174 ALA 174 170 170 ALA ALA A . n 
B 2 175 PRO 175 171 171 PRO PRO A . n 
B 2 176 GLU 176 172 172 GLU GLU A . n 
B 2 177 ILE 177 173 173 ILE ILE A . n 
B 2 178 LEU 178 174 174 LEU LEU A . n 
B 2 179 LEU 179 175 175 LEU LEU A . n 
B 2 180 GLY 180 176 176 GLY GLY A . n 
B 2 181 CYS 181 177 177 CYS CYS A . n 
B 2 182 LYS 182 178 178 LYS LYS A . n 
B 2 183 TYR 183 179 179 TYR TYR A . n 
B 2 184 TYR 184 180 180 TYR TYR A . n 
B 2 185 SER 185 181 181 SER SER A . n 
B 2 186 THR 186 182 182 THR THR A . n 
B 2 187 ALA 187 183 183 ALA ALA A . n 
B 2 188 VAL 188 184 184 VAL VAL A . n 
B 2 189 ASP 189 185 185 ASP ASP A . n 
B 2 190 ILE 190 186 186 ILE ILE A . n 
B 2 191 TRP 191 187 187 TRP TRP A . n 
B 2 192 SER 192 188 188 SER SER A . n 
B 2 193 LEU 193 189 189 LEU LEU A . n 
B 2 194 GLY 194 190 190 GLY GLY A . n 
B 2 195 CYS 195 191 191 CYS CYS A . n 
B 2 196 ILE 196 192 192 ILE ILE A . n 
B 2 197 PHE 197 193 193 PHE PHE A . n 
B 2 198 ALA 198 194 194 ALA ALA A . n 
B 2 199 GLU 199 195 195 GLU GLU A . n 
B 2 200 MET 200 196 196 MET MET A . n 
B 2 201 VAL 201 197 197 VAL VAL A . n 
B 2 202 THR 202 198 198 THR THR A . n 
B 2 203 ARG 203 199 199 ARG ARG A . n 
B 2 204 ARG 204 200 200 ARG ARG A . n 
B 2 205 ALA 205 201 201 ALA ALA A . n 
B 2 206 LEU 206 202 202 LEU LEU A . n 
B 2 207 PHE 207 203 203 PHE PHE A . n 
B 2 208 PRO 208 204 204 PRO PRO A . n 
B 2 209 GLY 209 205 205 GLY GLY A . n 
B 2 210 ASP 210 206 206 ASP ASP A . n 
B 2 211 SER 211 207 207 SER SER A . n 
B 2 212 GLU 212 208 208 GLU GLU A . n 
B 2 213 ILE 213 209 209 ILE ILE A . n 
B 2 214 ASP 214 210 210 ASP ASP A . n 
B 2 215 GLN 215 211 211 GLN GLN A . n 
B 2 216 LEU 216 212 212 LEU LEU A . n 
B 2 217 PHE 217 213 213 PHE PHE A . n 
B 2 218 ARG 218 214 214 ARG ARG A . n 
B 2 219 ILE 219 215 215 ILE ILE A . n 
B 2 220 PHE 220 216 216 PHE PHE A . n 
B 2 221 ARG 221 217 217 ARG ARG A . n 
B 2 222 THR 222 218 218 THR THR A . n 
B 2 223 LEU 223 219 219 LEU LEU A . n 
B 2 224 GLY 224 220 220 GLY GLY A . n 
B 2 225 THR 225 221 221 THR THR A . n 
B 2 226 PRO 226 222 222 PRO PRO A . n 
B 2 227 ASP 227 223 223 ASP ASP A . n 
B 2 228 GLU 228 224 224 GLU GLU A . n 
B 2 229 VAL 229 225 225 VAL VAL A . n 
B 2 230 VAL 230 226 226 VAL VAL A . n 
B 2 231 TRP 231 227 227 TRP TRP A . n 
B 2 232 PRO 232 228 228 PRO PRO A . n 
B 2 233 GLY 233 229 229 GLY GLY A . n 
B 2 234 VAL 234 230 230 VAL VAL A . n 
B 2 235 THR 235 231 231 THR THR A . n 
B 2 236 SER 236 232 232 SER SER A . n 
B 2 237 MET 237 233 233 MET MET A . n 
B 2 238 PRO 238 234 234 PRO PRO A . n 
B 2 239 ASP 239 235 235 ASP ASP A . n 
B 2 240 TYR 240 236 236 TYR TYR A . n 
B 2 241 LYS 241 237 237 LYS LYS A . n 
B 2 242 PRO 242 238 238 PRO PRO A . n 
B 2 243 SER 243 239 239 SER SER A . n 
B 2 244 PHE 244 240 240 PHE PHE A . n 
B 2 245 PRO 245 241 241 PRO PRO A . n 
B 2 246 LYS 246 242 242 LYS LYS A . n 
B 2 247 TRP 247 243 243 TRP TRP A . n 
B 2 248 ALA 248 244 244 ALA ALA A . n 
B 2 249 ARG 249 245 245 ARG ARG A . n 
B 2 250 GLN 250 246 246 GLN GLN A . n 
B 2 251 ASP 251 247 247 ASP ASP A . n 
B 2 252 PHE 252 248 248 PHE PHE A . n 
B 2 253 SER 253 249 249 SER SER A . n 
B 2 254 LYS 254 250 250 LYS LYS A . n 
B 2 255 VAL 255 251 251 VAL VAL A . n 
B 2 256 VAL 256 252 252 VAL VAL A . n 
B 2 257 PRO 257 253 253 PRO PRO A . n 
B 2 258 PRO 258 254 254 PRO PRO A . n 
B 2 259 LEU 259 255 255 LEU LEU A . n 
B 2 260 ASP 260 256 256 ASP ASP A . n 
B 2 261 GLU 261 257 257 GLU GLU A . n 
B 2 262 ASP 262 258 258 ASP ASP A . n 
B 2 263 GLY 263 259 259 GLY GLY A . n 
B 2 264 ARG 264 260 260 ARG ARG A . n 
B 2 265 SER 265 261 261 SER SER A . n 
B 2 266 LEU 266 262 262 LEU LEU A . n 
B 2 267 LEU 267 263 263 LEU LEU A . n 
B 2 268 SER 268 264 264 SER SER A . n 
B 2 269 GLN 269 265 265 GLN GLN A . n 
B 2 270 MET 270 266 266 MET MET A . n 
B 2 271 LEU 271 267 267 LEU LEU A . n 
B 2 272 HIS 272 268 268 HIS HIS A . n 
B 2 273 TYR 273 269 269 TYR TYR A . n 
B 2 274 ASP 274 270 270 ASP ASP A . n 
B 2 275 PRO 275 271 271 PRO PRO A . n 
B 2 276 ASN 276 272 272 ASN ASN A . n 
B 2 277 LYS 277 273 273 LYS LYS A . n 
B 2 278 ARG 278 274 274 ARG ARG A . n 
B 2 279 ILE 279 275 275 ILE ILE A . n 
B 2 280 SER 280 276 276 SER SER A . n 
B 2 281 ALA 281 277 277 ALA ALA A . n 
B 2 282 LYS 282 278 278 LYS LYS A . n 
B 2 283 ALA 283 279 279 ALA ALA A . n 
B 2 284 ALA 284 280 280 ALA ALA A . n 
B 2 285 LEU 285 281 281 LEU LEU A . n 
B 2 286 ALA 286 282 282 ALA ALA A . n 
B 2 287 HIS 287 283 283 HIS HIS A . n 
B 2 288 PRO 288 284 284 PRO PRO A . n 
B 2 289 PHE 289 285 285 PHE PHE A . n 
B 2 290 PHE 290 286 286 PHE PHE A . n 
B 2 291 GLN 291 287 287 GLN GLN A . n 
B 2 292 ASP 292 288 288 ASP ASP A . n 
B 2 293 VAL 293 289 289 VAL VAL A . n 
B 2 294 THR 294 290 290 THR THR A . n 
B 2 295 LYS 295 291 291 LYS LYS A . n 
B 2 296 PRO 296 292 292 PRO PRO A . n 
B 2 297 VAL 297 293 293 VAL VAL A . n 
B 2 298 PRO 298 294 294 PRO PRO A . n 
B 2 299 HIS 299 295 295 HIS HIS A . n 
B 2 300 LEU 300 296 296 LEU LEU A . n 
B 2 301 ARG 301 297 297 ARG ARG A . n 
B 2 302 LEU 302 298 298 LEU LEU A . n 
C 1 1   GLY 1   171 171 GLY GLY B . n 
C 1 2   VAL 2   172 172 VAL VAL B . n 
C 1 3   ASN 3   173 173 ASN ASN B . n 
C 1 4   GLU 4   174 174 GLU GLU B . n 
C 1 5   VAL 5   175 175 VAL VAL B . n 
C 1 6   PRO 6   176 176 PRO PRO B . n 
C 1 7   ASP 7   177 177 ASP ASP B . n 
C 1 8   TYR 8   178 178 TYR TYR B . n 
C 1 9   HIS 9   179 179 HIS HIS B . n 
C 1 10  GLU 10  180 180 GLU GLU B . n 
C 1 11  ASP 11  181 181 ASP ASP B . n 
C 1 12  ILE 12  182 182 ILE ILE B . n 
C 1 13  HIS 13  183 183 HIS HIS B . n 
C 1 14  THR 14  184 184 THR THR B . n 
C 1 15  TYR 15  185 185 TYR TYR B . n 
C 1 16  LEU 16  186 186 LEU LEU B . n 
C 1 17  ARG 17  187 187 ARG ARG B . n 
C 1 18  GLU 18  188 188 GLU GLU B . n 
C 1 19  MET 19  189 189 MET MET B . n 
C 1 20  GLU 20  190 190 GLU GLU B . n 
C 1 21  VAL 21  191 191 VAL VAL B . n 
C 1 22  LYS 22  192 192 LYS LYS B . n 
C 1 23  CYS 23  193 193 CYS CYS B . n 
C 1 24  LYS 24  194 194 LYS LYS B . n 
C 1 25  PRO 25  195 195 PRO PRO B . n 
C 1 26  LYS 26  196 196 LYS LYS B . n 
C 1 27  VAL 27  197 197 VAL VAL B . n 
C 1 28  GLY 28  198 198 GLY GLY B . n 
C 1 29  TYR 29  199 199 TYR TYR B . n 
C 1 30  MET 30  200 200 MET MET B . n 
C 1 31  LYS 31  201 201 LYS LYS B . n 
C 1 32  LYS 32  202 202 LYS LYS B . n 
C 1 33  GLN 33  203 203 GLN GLN B . n 
C 1 34  PRO 34  204 204 PRO PRO B . n 
C 1 35  ASP 35  205 205 ASP ASP B . n 
C 1 36  ILE 36  206 206 ILE ILE B . n 
C 1 37  THR 37  207 207 THR THR B . n 
C 1 38  ASN 38  208 208 ASN ASN B . n 
C 1 39  SER 39  209 209 SER SER B . n 
C 1 40  MET 40  210 210 MET MET B . n 
C 1 41  ARG 41  211 211 ARG ARG B . n 
C 1 42  ALA 42  212 212 ALA ALA B . n 
C 1 43  ILE 43  213 213 ILE ILE B . n 
C 1 44  LEU 44  214 214 LEU LEU B . n 
C 1 45  VAL 45  215 215 VAL VAL B . n 
C 1 46  ASP 46  216 216 ASP ASP B . n 
C 1 47  TRP 47  217 217 TRP TRP B . n 
C 1 48  LEU 48  218 218 LEU LEU B . n 
C 1 49  VAL 49  219 219 VAL VAL B . n 
C 1 50  GLU 50  220 220 GLU GLU B . n 
C 1 51  VAL 51  221 221 VAL VAL B . n 
C 1 52  GLY 52  222 222 GLY GLY B . n 
C 1 53  GLU 53  223 223 GLU GLU B . n 
C 1 54  GLU 54  224 224 GLU GLU B . n 
C 1 55  TYR 55  225 225 TYR TYR B . n 
C 1 56  LYS 56  226 226 LYS LYS B . n 
C 1 57  LEU 57  227 227 LEU LEU B . n 
C 1 58  GLN 58  228 228 GLN GLN B . n 
C 1 59  ASN 59  229 229 ASN ASN B . n 
C 1 60  GLU 60  230 230 GLU GLU B . n 
C 1 61  THR 61  231 231 THR THR B . n 
C 1 62  LEU 62  232 232 LEU LEU B . n 
C 1 63  HIS 63  233 233 HIS HIS B . n 
C 1 64  LEU 64  234 234 LEU LEU B . n 
C 1 65  ALA 65  235 235 ALA ALA B . n 
C 1 66  VAL 66  236 236 VAL VAL B . n 
C 1 67  ASN 67  237 237 ASN ASN B . n 
C 1 68  TYR 68  238 238 TYR TYR B . n 
C 1 69  ILE 69  239 239 ILE ILE B . n 
C 1 70  ASP 70  240 240 ASP ASP B . n 
C 1 71  ARG 71  241 241 ARG ARG B . n 
C 1 72  PHE 72  242 242 PHE PHE B . n 
C 1 73  LEU 73  243 243 LEU LEU B . n 
C 1 74  SER 74  244 244 SER SER B . n 
C 1 75  SER 75  245 245 SER SER B . n 
C 1 76  MET 76  246 246 MET MET B . n 
C 1 77  SER 77  247 247 SER SER B . n 
C 1 78  VAL 78  248 248 VAL VAL B . n 
C 1 79  LEU 79  249 249 LEU LEU B . n 
C 1 80  ARG 80  250 250 ARG ARG B . n 
C 1 81  GLY 81  251 251 GLY GLY B . n 
C 1 82  LYS 82  252 252 LYS LYS B . n 
C 1 83  LEU 83  253 253 LEU LEU B . n 
C 1 84  GLN 84  254 254 GLN GLN B . n 
C 1 85  LEU 85  255 255 LEU LEU B . n 
C 1 86  VAL 86  256 256 VAL VAL B . n 
C 1 87  GLY 87  257 257 GLY GLY B . n 
C 1 88  THR 88  258 258 THR THR B . n 
C 1 89  ALA 89  259 259 ALA ALA B . n 
C 1 90  ALA 90  260 260 ALA ALA B . n 
C 1 91  MET 91  261 261 MET MET B . n 
C 1 92  LEU 92  262 262 LEU LEU B . n 
C 1 93  LEU 93  263 263 LEU LEU B . n 
C 1 94  ALA 94  264 264 ALA ALA B . n 
C 1 95  SER 95  265 265 SER SER B . n 
C 1 96  LYS 96  266 266 LYS LYS B . n 
C 1 97  PHE 97  267 267 PHE PHE B . n 
C 1 98  GLU 98  268 268 GLU GLU B . n 
C 1 99  GLU 99  269 269 GLU GLU B . n 
C 1 100 ILE 100 270 270 ILE ILE B . n 
C 1 101 TYR 101 271 271 TYR TYR B . n 
C 1 102 PRO 102 272 272 PRO PRO B . n 
C 1 103 PRO 103 273 273 PRO PRO B . n 
C 1 104 GLU 104 274 274 GLU GLU B . n 
C 1 105 VAL 105 275 275 VAL VAL B . n 
C 1 106 ALA 106 276 276 ALA ALA B . n 
C 1 107 GLU 107 277 277 GLU GLU B . n 
C 1 108 PHE 108 278 278 PHE PHE B . n 
C 1 109 VAL 109 279 279 VAL VAL B . n 
C 1 110 TYR 110 280 280 TYR TYR B . n 
C 1 111 ILE 111 281 281 ILE ILE B . n 
C 1 112 THR 112 282 282 THR THR B . n 
C 1 113 ASP 113 283 283 ASP ASP B . n 
C 1 114 ASP 114 284 284 ASP ASP B . n 
C 1 115 THR 115 285 285 THR THR B . n 
C 1 116 TYR 116 286 286 TYR TYR B . n 
C 1 117 THR 117 287 287 THR THR B . n 
C 1 118 LYS 118 288 288 LYS LYS B . n 
C 1 119 LYS 119 289 289 LYS LYS B . n 
C 1 120 GLN 120 290 290 GLN GLN B . n 
C 1 121 VAL 121 291 291 VAL VAL B . n 
C 1 122 LEU 122 292 292 LEU LEU B . n 
C 1 123 ARG 123 293 293 ARG ARG B . n 
C 1 124 MET 124 294 294 MET MET B . n 
C 1 125 GLU 125 295 295 GLU GLU B . n 
C 1 126 HIS 126 296 296 HIS HIS B . n 
C 1 127 LEU 127 297 297 LEU LEU B . n 
C 1 128 VAL 128 298 298 VAL VAL B . n 
C 1 129 LEU 129 299 299 LEU LEU B . n 
C 1 130 LYS 130 300 300 LYS LYS B . n 
C 1 131 VAL 131 301 301 VAL VAL B . n 
C 1 132 LEU 132 302 302 LEU LEU B . n 
C 1 133 ALA 133 303 303 ALA ALA B . n 
C 1 134 PHE 134 304 304 PHE PHE B . n 
C 1 135 ASP 135 305 305 ASP ASP B . n 
C 1 136 LEU 136 306 306 LEU LEU B . n 
C 1 137 ALA 137 307 307 ALA ALA B . n 
C 1 138 ALA 138 308 308 ALA ALA B . n 
C 1 139 PRO 139 309 309 PRO PRO B . n 
C 1 140 THR 140 310 310 THR THR B . n 
C 1 141 ILE 141 311 311 ILE ILE B . n 
C 1 142 ASN 142 312 312 ASN ASN B . n 
C 1 143 GLN 143 313 313 GLN GLN B . n 
C 1 144 PHE 144 314 314 PHE PHE B . n 
C 1 145 LEU 145 315 315 LEU LEU B . n 
C 1 146 THR 146 316 316 THR THR B . n 
C 1 147 GLN 147 317 317 GLN GLN B . n 
C 1 148 TYR 148 318 318 TYR TYR B . n 
C 1 149 PHE 149 319 319 PHE PHE B . n 
C 1 150 LEU 150 320 320 LEU LEU B . n 
C 1 151 HIS 151 321 321 HIS HIS B . n 
C 1 152 GLN 152 322 322 GLN GLN B . n 
C 1 153 GLN 153 323 323 GLN GLN B . n 
C 1 154 PRO 154 324 324 PRO PRO B . n 
C 1 155 ALA 155 325 325 ALA ALA B . n 
C 1 156 ASN 156 326 326 ASN ASN B . n 
C 1 157 CYS 157 327 327 CYS CYS B . n 
C 1 158 LYS 158 328 328 LYS LYS B . n 
C 1 159 VAL 159 329 329 VAL VAL B . n 
C 1 160 GLU 160 330 330 GLU GLU B . n 
C 1 161 SER 161 331 331 SER SER B . n 
C 1 162 LEU 162 332 332 LEU LEU B . n 
C 1 163 ALA 163 333 333 ALA ALA B . n 
C 1 164 MET 164 334 334 MET MET B . n 
C 1 165 PHE 165 335 335 PHE PHE B . n 
C 1 166 LEU 166 336 336 LEU LEU B . n 
C 1 167 GLY 167 337 337 GLY GLY B . n 
C 1 168 GLU 168 338 338 GLU GLU B . n 
C 1 169 LEU 169 339 339 LEU LEU B . n 
C 1 170 SER 170 340 340 SER SER B . n 
C 1 171 LEU 171 341 341 LEU LEU B . n 
C 1 172 ILE 172 342 342 ILE ILE B . n 
C 1 173 ASP 173 343 343 ASP ASP B . n 
C 1 174 ALA 174 344 344 ALA ALA B . n 
C 1 175 ASP 175 345 345 ASP ASP B . n 
C 1 176 PRO 176 346 346 PRO PRO B . n 
C 1 177 TYR 177 347 347 TYR TYR B . n 
C 1 178 LEU 178 348 348 LEU LEU B . n 
C 1 179 LYS 179 349 349 LYS LYS B . n 
C 1 180 TYR 180 350 350 TYR TYR B . n 
C 1 181 LEU 181 351 351 LEU LEU B . n 
C 1 182 PRO 182 352 352 PRO PRO B . n 
C 1 183 SER 183 353 353 SER SER B . n 
C 1 184 VAL 184 354 354 VAL VAL B . n 
C 1 185 ILE 185 355 355 ILE ILE B . n 
C 1 186 ALA 186 356 356 ALA ALA B . n 
C 1 187 ALA 187 357 357 ALA ALA B . n 
C 1 188 ALA 188 358 358 ALA ALA B . n 
C 1 189 ALA 189 359 359 ALA ALA B . n 
C 1 190 PHE 190 360 360 PHE PHE B . n 
C 1 191 HIS 191 361 361 HIS HIS B . n 
C 1 192 LEU 192 362 362 LEU LEU B . n 
C 1 193 ALA 193 363 363 ALA ALA B . n 
C 1 194 LEU 194 364 364 LEU LEU B . n 
C 1 195 TYR 195 365 365 TYR TYR B . n 
C 1 196 THR 196 366 366 THR THR B . n 
C 1 197 VAL 197 367 367 VAL VAL B . n 
C 1 198 THR 198 368 368 THR THR B . n 
C 1 199 GLY 199 369 369 GLY GLY B . n 
C 1 200 GLN 200 370 370 GLN GLN B . n 
C 1 201 SER 201 371 371 SER SER B . n 
C 1 202 TRP 202 372 372 TRP TRP B . n 
C 1 203 PRO 203 373 373 PRO PRO B . n 
C 1 204 GLU 204 374 374 GLU GLU B . n 
C 1 205 SER 205 375 375 SER SER B . n 
C 1 206 LEU 206 376 376 LEU LEU B . n 
C 1 207 VAL 207 377 377 VAL VAL B . n 
C 1 208 GLN 208 378 378 GLN GLN B . n 
C 1 209 LYS 209 379 379 LYS LYS B . n 
C 1 210 THR 210 380 380 THR THR B . n 
C 1 211 GLY 211 381 381 GLY GLY B . n 
C 1 212 TYR 212 382 382 TYR TYR B . n 
C 1 213 THR 213 383 383 THR THR B . n 
C 1 214 LEU 214 384 384 LEU LEU B . n 
C 1 215 GLU 215 385 385 GLU GLU B . n 
C 1 216 THR 216 386 386 THR THR B . n 
C 1 217 LEU 217 387 387 LEU LEU B . n 
C 1 218 LYS 218 388 388 LYS LYS B . n 
C 1 219 PRO 219 389 389 PRO PRO B . n 
C 1 220 CYS 220 390 390 CYS CYS B . n 
C 1 221 LEU 221 391 391 LEU LEU B . n 
C 1 222 LEU 222 392 392 LEU LEU B . n 
C 1 223 ASP 223 393 393 ASP ASP B . n 
C 1 224 LEU 224 394 394 LEU LEU B . n 
C 1 225 HIS 225 395 395 HIS HIS B . n 
C 1 226 GLN 226 396 396 GLN GLN B . n 
C 1 227 THR 227 397 397 THR THR B . n 
C 1 228 TYR 228 398 398 TYR TYR B . n 
C 1 229 LEU 229 399 399 LEU LEU B . n 
C 1 230 ARG 230 400 400 ARG ARG B . n 
C 1 231 ALA 231 401 401 ALA ALA B . n 
C 1 232 PRO 232 402 402 PRO PRO B . n 
C 1 233 GLN 233 403 403 GLN GLN B . n 
C 1 234 HIS 234 404 404 HIS HIS B . n 
C 1 235 ALA 235 405 405 ALA ALA B . n 
C 1 236 GLN 236 406 406 GLN GLN B . n 
C 1 237 GLN 237 407 407 GLN GLN B . n 
C 1 238 SER 238 408 408 SER SER B . n 
C 1 239 ILE 239 409 409 ILE ILE B . n 
C 1 240 ARG 240 410 410 ARG ARG B . n 
C 1 241 GLU 241 411 411 GLU GLU B . n 
C 1 242 LYS 242 412 412 LYS LYS B . n 
C 1 243 TYR 243 413 413 TYR TYR B . n 
C 1 244 LYS 244 414 414 LYS LYS B . n 
C 1 245 ASN 245 415 415 ASN ASN B . n 
C 1 246 SER 246 416 416 SER SER B . n 
C 1 247 LYS 247 417 417 LYS LYS B . n 
C 1 248 TYR 248 418 418 TYR TYR B . n 
C 1 249 HIS 249 419 419 HIS HIS B . n 
C 1 250 GLY 250 420 420 GLY GLY B . n 
C 1 251 VAL 251 421 421 VAL VAL B . n 
C 1 252 SER 252 422 422 SER SER B . n 
C 1 253 LEU 253 423 423 LEU LEU B . n 
C 1 254 LEU 254 424 424 LEU LEU B . n 
C 1 255 ASN 255 425 425 ASN ASN B . n 
C 1 256 PRO 256 426 426 PRO PRO B . n 
C 1 257 PRO 257 427 427 PRO PRO B . n 
C 1 258 GLU 258 428 428 GLU GLU B . n 
C 1 259 THR 259 429 429 THR THR B . n 
C 1 260 LEU 260 430 430 LEU LEU B . n 
C 1 261 ASN 261 431 431 ASN ASN B . n 
C 1 262 VAL 262 432 432 VAL VAL B . n 
C 1 263 HIS 263 433 ?   ?   ?   B . n 
C 1 264 HIS 264 434 ?   ?   ?   B . n 
C 1 265 HIS 265 435 ?   ?   ?   B . n 
C 1 266 HIS 266 436 ?   ?   ?   B . n 
C 1 267 HIS 267 437 ?   ?   ?   B . n 
C 1 268 HIS 268 438 ?   ?   ?   B . n 
D 2 1   GLY 1   -3  ?   ?   ?   C . n 
D 2 2   PRO 2   -2  ?   ?   ?   C . n 
D 2 3   GLY 3   -1  ?   ?   ?   C . n 
D 2 4   SER 4   0   0   SER SER C . n 
D 2 5   MET 5   1   1   MET MET C . n 
D 2 6   GLU 6   2   2   GLU GLU C . n 
D 2 7   ASN 7   3   3   ASN ASN C . n 
D 2 8   PHE 8   4   4   PHE PHE C . n 
D 2 9   GLN 9   5   5   GLN GLN C . n 
D 2 10  LYS 10  6   6   LYS LYS C . n 
D 2 11  VAL 11  7   7   VAL VAL C . n 
D 2 12  GLU 12  8   8   GLU GLU C . n 
D 2 13  LYS 13  9   9   LYS LYS C . n 
D 2 14  ILE 14  10  10  ILE ILE C . n 
D 2 15  GLY 15  11  11  GLY GLY C . n 
D 2 16  GLU 16  12  12  GLU GLU C . n 
D 2 17  GLY 17  13  13  GLY GLY C . n 
D 2 18  THR 18  14  14  THR THR C . n 
D 2 19  TYR 19  15  15  TYR TYR C . n 
D 2 20  GLY 20  16  16  GLY GLY C . n 
D 2 21  VAL 21  17  17  VAL VAL C . n 
D 2 22  VAL 22  18  18  VAL VAL C . n 
D 2 23  TYR 23  19  19  TYR TYR C . n 
D 2 24  LYS 24  20  20  LYS LYS C . n 
D 2 25  ALA 25  21  21  ALA ALA C . n 
D 2 26  ARG 26  22  22  ARG ARG C . n 
D 2 27  ASN 27  23  23  ASN ASN C . n 
D 2 28  LYS 28  24  24  LYS LYS C . n 
D 2 29  LEU 29  25  25  LEU LEU C . n 
D 2 30  THR 30  26  26  THR THR C . n 
D 2 31  GLY 31  27  27  GLY GLY C . n 
D 2 32  GLU 32  28  28  GLU GLU C . n 
D 2 33  VAL 33  29  29  VAL VAL C . n 
D 2 34  VAL 34  30  30  VAL VAL C . n 
D 2 35  ALA 35  31  31  ALA ALA C . n 
D 2 36  LEU 36  32  32  LEU LEU C . n 
D 2 37  LYS 37  33  33  LYS LYS C . n 
D 2 38  LYS 38  34  34  LYS LYS C . n 
D 2 39  ILE 39  35  35  ILE ILE C . n 
D 2 40  ARG 40  36  36  ARG ARG C . n 
D 2 41  LEU 41  37  37  LEU LEU C . n 
D 2 42  ASP 42  38  38  ASP ASP C . n 
D 2 43  THR 43  39  39  THR THR C . n 
D 2 44  GLU 44  40  40  GLU GLU C . n 
D 2 45  THR 45  41  41  THR THR C . n 
D 2 46  GLU 46  42  42  GLU GLU C . n 
D 2 47  GLY 47  43  43  GLY GLY C . n 
D 2 48  VAL 48  44  44  VAL VAL C . n 
D 2 49  PRO 49  45  45  PRO PRO C . n 
D 2 50  SER 50  46  46  SER SER C . n 
D 2 51  THR 51  47  47  THR THR C . n 
D 2 52  ALA 52  48  48  ALA ALA C . n 
D 2 53  ILE 53  49  49  ILE ILE C . n 
D 2 54  ARG 54  50  50  ARG ARG C . n 
D 2 55  GLU 55  51  51  GLU GLU C . n 
D 2 56  ILE 56  52  52  ILE ILE C . n 
D 2 57  SER 57  53  53  SER SER C . n 
D 2 58  LEU 58  54  54  LEU LEU C . n 
D 2 59  LEU 59  55  55  LEU LEU C . n 
D 2 60  LYS 60  56  56  LYS LYS C . n 
D 2 61  GLU 61  57  57  GLU GLU C . n 
D 2 62  LEU 62  58  58  LEU LEU C . n 
D 2 63  ASN 63  59  59  ASN ASN C . n 
D 2 64  HIS 64  60  60  HIS HIS C . n 
D 2 65  PRO 65  61  61  PRO PRO C . n 
D 2 66  ASN 66  62  62  ASN ASN C . n 
D 2 67  ILE 67  63  63  ILE ILE C . n 
D 2 68  VAL 68  64  64  VAL VAL C . n 
D 2 69  LYS 69  65  65  LYS LYS C . n 
D 2 70  LEU 70  66  66  LEU LEU C . n 
D 2 71  LEU 71  67  67  LEU LEU C . n 
D 2 72  ASP 72  68  68  ASP ASP C . n 
D 2 73  VAL 73  69  69  VAL VAL C . n 
D 2 74  ILE 74  70  70  ILE ILE C . n 
D 2 75  HIS 75  71  71  HIS HIS C . n 
D 2 76  THR 76  72  72  THR THR C . n 
D 2 77  GLU 77  73  73  GLU GLU C . n 
D 2 78  ASN 78  74  74  ASN ASN C . n 
D 2 79  LYS 79  75  75  LYS LYS C . n 
D 2 80  LEU 80  76  76  LEU LEU C . n 
D 2 81  TYR 81  77  77  TYR TYR C . n 
D 2 82  LEU 82  78  78  LEU LEU C . n 
D 2 83  VAL 83  79  79  VAL VAL C . n 
D 2 84  PHE 84  80  80  PHE PHE C . n 
D 2 85  GLU 85  81  81  GLU GLU C . n 
D 2 86  PHE 86  82  82  PHE PHE C . n 
D 2 87  LEU 87  83  83  LEU LEU C . n 
D 2 88  HIS 88  84  84  HIS HIS C . n 
D 2 89  GLN 89  85  85  GLN GLN C . n 
D 2 90  ASP 90  86  86  ASP ASP C . n 
D 2 91  LEU 91  87  87  LEU LEU C . n 
D 2 92  LYS 92  88  88  LYS LYS C . n 
D 2 93  LYS 93  89  89  LYS LYS C . n 
D 2 94  PHE 94  90  90  PHE PHE C . n 
D 2 95  MET 95  91  91  MET MET C . n 
D 2 96  ASP 96  92  92  ASP ASP C . n 
D 2 97  ALA 97  93  93  ALA ALA C . n 
D 2 98  SER 98  94  94  SER SER C . n 
D 2 99  ALA 99  95  95  ALA ALA C . n 
D 2 100 LEU 100 96  96  LEU LEU C . n 
D 2 101 THR 101 97  97  THR THR C . n 
D 2 102 GLY 102 98  98  GLY GLY C . n 
D 2 103 ILE 103 99  99  ILE ILE C . n 
D 2 104 PRO 104 100 100 PRO PRO C . n 
D 2 105 LEU 105 101 101 LEU LEU C . n 
D 2 106 PRO 106 102 102 PRO PRO C . n 
D 2 107 LEU 107 103 103 LEU LEU C . n 
D 2 108 ILE 108 104 104 ILE ILE C . n 
D 2 109 LYS 109 105 105 LYS LYS C . n 
D 2 110 SER 110 106 106 SER SER C . n 
D 2 111 TYR 111 107 107 TYR TYR C . n 
D 2 112 LEU 112 108 108 LEU LEU C . n 
D 2 113 PHE 113 109 109 PHE PHE C . n 
D 2 114 GLN 114 110 110 GLN GLN C . n 
D 2 115 LEU 115 111 111 LEU LEU C . n 
D 2 116 LEU 116 112 112 LEU LEU C . n 
D 2 117 GLN 117 113 113 GLN GLN C . n 
D 2 118 GLY 118 114 114 GLY GLY C . n 
D 2 119 LEU 119 115 115 LEU LEU C . n 
D 2 120 ALA 120 116 116 ALA ALA C . n 
D 2 121 PHE 121 117 117 PHE PHE C . n 
D 2 122 CYS 122 118 118 CYS CYS C . n 
D 2 123 HIS 123 119 119 HIS HIS C . n 
D 2 124 SER 124 120 120 SER SER C . n 
D 2 125 HIS 125 121 121 HIS HIS C . n 
D 2 126 ARG 126 122 122 ARG ARG C . n 
D 2 127 VAL 127 123 123 VAL VAL C . n 
D 2 128 LEU 128 124 124 LEU LEU C . n 
D 2 129 HIS 129 125 125 HIS HIS C . n 
D 2 130 ARG 130 126 126 ARG ARG C . n 
D 2 131 ASP 131 127 127 ASP ASP C . n 
D 2 132 LEU 132 128 128 LEU LEU C . n 
D 2 133 LYS 133 129 129 LYS LYS C . n 
D 2 134 PRO 134 130 130 PRO PRO C . n 
D 2 135 GLN 135 131 131 GLN GLN C . n 
D 2 136 ASN 136 132 132 ASN ASN C . n 
D 2 137 LEU 137 133 133 LEU LEU C . n 
D 2 138 LEU 138 134 134 LEU LEU C . n 
D 2 139 ILE 139 135 135 ILE ILE C . n 
D 2 140 ASN 140 136 136 ASN ASN C . n 
D 2 141 THR 141 137 137 THR THR C . n 
D 2 142 GLU 142 138 138 GLU GLU C . n 
D 2 143 GLY 143 139 139 GLY GLY C . n 
D 2 144 ALA 144 140 140 ALA ALA C . n 
D 2 145 ILE 145 141 141 ILE ILE C . n 
D 2 146 LYS 146 142 142 LYS LYS C . n 
D 2 147 LEU 147 143 143 LEU LEU C . n 
D 2 148 ALA 148 144 144 ALA ALA C . n 
D 2 149 ASP 149 145 145 ASP ASP C . n 
D 2 150 PHE 150 146 146 PHE PHE C . n 
D 2 151 GLY 151 147 147 GLY GLY C . n 
D 2 152 LEU 152 148 148 LEU LEU C . n 
D 2 153 ALA 153 149 149 ALA ALA C . n 
D 2 154 ARG 154 150 150 ARG ARG C . n 
D 2 155 ALA 155 151 151 ALA ALA C . n 
D 2 156 PHE 156 152 152 PHE PHE C . n 
D 2 157 GLY 157 153 153 GLY GLY C . n 
D 2 158 VAL 158 154 154 VAL VAL C . n 
D 2 159 PRO 159 155 155 PRO PRO C . n 
D 2 160 VAL 160 156 156 VAL VAL C . n 
D 2 161 ARG 161 157 157 ARG ARG C . n 
D 2 162 THR 162 158 158 THR THR C . n 
D 2 163 TYR 163 159 159 TYR TYR C . n 
D 2 164 TPO 164 160 160 TPO TPO C . n 
D 2 165 HIS 165 161 161 HIS HIS C . n 
D 2 166 GLU 166 162 162 GLU GLU C . n 
D 2 167 VAL 167 163 163 VAL VAL C . n 
D 2 168 VAL 168 164 164 VAL VAL C . n 
D 2 169 THR 169 165 165 THR THR C . n 
D 2 170 LEU 170 166 166 LEU LEU C . n 
D 2 171 TRP 171 167 167 TRP TRP C . n 
D 2 172 TYR 172 168 168 TYR TYR C . n 
D 2 173 ARG 173 169 169 ARG ARG C . n 
D 2 174 ALA 174 170 170 ALA ALA C . n 
D 2 175 PRO 175 171 171 PRO PRO C . n 
D 2 176 GLU 176 172 172 GLU GLU C . n 
D 2 177 ILE 177 173 173 ILE ILE C . n 
D 2 178 LEU 178 174 174 LEU LEU C . n 
D 2 179 LEU 179 175 175 LEU LEU C . n 
D 2 180 GLY 180 176 176 GLY GLY C . n 
D 2 181 CYS 181 177 177 CYS CYS C . n 
D 2 182 LYS 182 178 178 LYS LYS C . n 
D 2 183 TYR 183 179 179 TYR TYR C . n 
D 2 184 TYR 184 180 180 TYR TYR C . n 
D 2 185 SER 185 181 181 SER SER C . n 
D 2 186 THR 186 182 182 THR THR C . n 
D 2 187 ALA 187 183 183 ALA ALA C . n 
D 2 188 VAL 188 184 184 VAL VAL C . n 
D 2 189 ASP 189 185 185 ASP ASP C . n 
D 2 190 ILE 190 186 186 ILE ILE C . n 
D 2 191 TRP 191 187 187 TRP TRP C . n 
D 2 192 SER 192 188 188 SER SER C . n 
D 2 193 LEU 193 189 189 LEU LEU C . n 
D 2 194 GLY 194 190 190 GLY GLY C . n 
D 2 195 CYS 195 191 191 CYS CYS C . n 
D 2 196 ILE 196 192 192 ILE ILE C . n 
D 2 197 PHE 197 193 193 PHE PHE C . n 
D 2 198 ALA 198 194 194 ALA ALA C . n 
D 2 199 GLU 199 195 195 GLU GLU C . n 
D 2 200 MET 200 196 196 MET MET C . n 
D 2 201 VAL 201 197 197 VAL VAL C . n 
D 2 202 THR 202 198 198 THR THR C . n 
D 2 203 ARG 203 199 199 ARG ARG C . n 
D 2 204 ARG 204 200 200 ARG ARG C . n 
D 2 205 ALA 205 201 201 ALA ALA C . n 
D 2 206 LEU 206 202 202 LEU LEU C . n 
D 2 207 PHE 207 203 203 PHE PHE C . n 
D 2 208 PRO 208 204 204 PRO PRO C . n 
D 2 209 GLY 209 205 205 GLY GLY C . n 
D 2 210 ASP 210 206 206 ASP ASP C . n 
D 2 211 SER 211 207 207 SER SER C . n 
D 2 212 GLU 212 208 208 GLU GLU C . n 
D 2 213 ILE 213 209 209 ILE ILE C . n 
D 2 214 ASP 214 210 210 ASP ASP C . n 
D 2 215 GLN 215 211 211 GLN GLN C . n 
D 2 216 LEU 216 212 212 LEU LEU C . n 
D 2 217 PHE 217 213 213 PHE PHE C . n 
D 2 218 ARG 218 214 214 ARG ARG C . n 
D 2 219 ILE 219 215 215 ILE ILE C . n 
D 2 220 PHE 220 216 216 PHE PHE C . n 
D 2 221 ARG 221 217 217 ARG ARG C . n 
D 2 222 THR 222 218 218 THR THR C . n 
D 2 223 LEU 223 219 219 LEU LEU C . n 
D 2 224 GLY 224 220 220 GLY GLY C . n 
D 2 225 THR 225 221 221 THR THR C . n 
D 2 226 PRO 226 222 222 PRO PRO C . n 
D 2 227 ASP 227 223 223 ASP ASP C . n 
D 2 228 GLU 228 224 224 GLU GLU C . n 
D 2 229 VAL 229 225 225 VAL VAL C . n 
D 2 230 VAL 230 226 226 VAL VAL C . n 
D 2 231 TRP 231 227 227 TRP TRP C . n 
D 2 232 PRO 232 228 228 PRO PRO C . n 
D 2 233 GLY 233 229 229 GLY GLY C . n 
D 2 234 VAL 234 230 230 VAL VAL C . n 
D 2 235 THR 235 231 231 THR THR C . n 
D 2 236 SER 236 232 232 SER SER C . n 
D 2 237 MET 237 233 233 MET MET C . n 
D 2 238 PRO 238 234 234 PRO PRO C . n 
D 2 239 ASP 239 235 235 ASP ASP C . n 
D 2 240 TYR 240 236 236 TYR TYR C . n 
D 2 241 LYS 241 237 237 LYS LYS C . n 
D 2 242 PRO 242 238 238 PRO PRO C . n 
D 2 243 SER 243 239 239 SER SER C . n 
D 2 244 PHE 244 240 240 PHE PHE C . n 
D 2 245 PRO 245 241 241 PRO PRO C . n 
D 2 246 LYS 246 242 242 LYS LYS C . n 
D 2 247 TRP 247 243 243 TRP TRP C . n 
D 2 248 ALA 248 244 244 ALA ALA C . n 
D 2 249 ARG 249 245 245 ARG ARG C . n 
D 2 250 GLN 250 246 246 GLN GLN C . n 
D 2 251 ASP 251 247 247 ASP ASP C . n 
D 2 252 PHE 252 248 248 PHE PHE C . n 
D 2 253 SER 253 249 249 SER SER C . n 
D 2 254 LYS 254 250 250 LYS LYS C . n 
D 2 255 VAL 255 251 251 VAL VAL C . n 
D 2 256 VAL 256 252 252 VAL VAL C . n 
D 2 257 PRO 257 253 253 PRO PRO C . n 
D 2 258 PRO 258 254 254 PRO PRO C . n 
D 2 259 LEU 259 255 255 LEU LEU C . n 
D 2 260 ASP 260 256 256 ASP ASP C . n 
D 2 261 GLU 261 257 257 GLU GLU C . n 
D 2 262 ASP 262 258 258 ASP ASP C . n 
D 2 263 GLY 263 259 259 GLY GLY C . n 
D 2 264 ARG 264 260 260 ARG ARG C . n 
D 2 265 SER 265 261 261 SER SER C . n 
D 2 266 LEU 266 262 262 LEU LEU C . n 
D 2 267 LEU 267 263 263 LEU LEU C . n 
D 2 268 SER 268 264 264 SER SER C . n 
D 2 269 GLN 269 265 265 GLN GLN C . n 
D 2 270 MET 270 266 266 MET MET C . n 
D 2 271 LEU 271 267 267 LEU LEU C . n 
D 2 272 HIS 272 268 268 HIS HIS C . n 
D 2 273 TYR 273 269 269 TYR TYR C . n 
D 2 274 ASP 274 270 270 ASP ASP C . n 
D 2 275 PRO 275 271 271 PRO PRO C . n 
D 2 276 ASN 276 272 272 ASN ASN C . n 
D 2 277 LYS 277 273 273 LYS LYS C . n 
D 2 278 ARG 278 274 274 ARG ARG C . n 
D 2 279 ILE 279 275 275 ILE ILE C . n 
D 2 280 SER 280 276 276 SER SER C . n 
D 2 281 ALA 281 277 277 ALA ALA C . n 
D 2 282 LYS 282 278 278 LYS LYS C . n 
D 2 283 ALA 283 279 279 ALA ALA C . n 
D 2 284 ALA 284 280 280 ALA ALA C . n 
D 2 285 LEU 285 281 281 LEU LEU C . n 
D 2 286 ALA 286 282 282 ALA ALA C . n 
D 2 287 HIS 287 283 283 HIS HIS C . n 
D 2 288 PRO 288 284 284 PRO PRO C . n 
D 2 289 PHE 289 285 285 PHE PHE C . n 
D 2 290 PHE 290 286 286 PHE PHE C . n 
D 2 291 GLN 291 287 287 GLN GLN C . n 
D 2 292 ASP 292 288 288 ASP ASP C . n 
D 2 293 VAL 293 289 289 VAL VAL C . n 
D 2 294 THR 294 290 290 THR THR C . n 
D 2 295 LYS 295 291 291 LYS LYS C . n 
D 2 296 PRO 296 292 292 PRO PRO C . n 
D 2 297 VAL 297 293 293 VAL VAL C . n 
D 2 298 PRO 298 294 294 PRO PRO C . n 
D 2 299 HIS 299 295 295 HIS HIS C . n 
D 2 300 LEU 300 296 296 LEU LEU C . n 
D 2 301 ARG 301 297 ?   ?   ?   C . n 
D 2 302 LEU 302 298 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        IIS 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   IIS 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 IIS 1  601 601 IIS DRG A . 
F 3 IIS 1  602 603 IIS DRG A . 
G 3 IIS 1  603 605 IIS DRG A . 
H 3 IIS 1  301 602 IIS DRG C . 
I 3 IIS 1  302 604 IIS DRG C . 
J 3 IIS 1  303 704 IIS DRG C . 
K 4 HOH 1  501 547 HOH HOH D . 
K 4 HOH 2  502 501 HOH HOH D . 
K 4 HOH 3  503 522 HOH HOH D . 
K 4 HOH 4  504 502 HOH HOH D . 
K 4 HOH 5  505 429 HOH HOH D . 
K 4 HOH 6  506 505 HOH HOH D . 
K 4 HOH 7  507 7   HOH HOH D . 
K 4 HOH 8  508 580 HOH HOH D . 
K 4 HOH 9  509 532 HOH HOH D . 
K 4 HOH 10 510 13  HOH HOH D . 
K 4 HOH 11 511 508 HOH HOH D . 
K 4 HOH 12 512 521 HOH HOH D . 
K 4 HOH 13 513 507 HOH HOH D . 
K 4 HOH 14 514 512 HOH HOH D . 
K 4 HOH 15 515 455 HOH HOH D . 
K 4 HOH 16 516 474 HOH HOH D . 
K 4 HOH 17 517 131 HOH HOH D . 
K 4 HOH 18 518 555 HOH HOH D . 
K 4 HOH 19 519 504 HOH HOH D . 
K 4 HOH 20 520 529 HOH HOH D . 
K 4 HOH 21 521 511 HOH HOH D . 
K 4 HOH 22 522 434 HOH HOH D . 
K 4 HOH 23 523 520 HOH HOH D . 
K 4 HOH 24 524 537 HOH HOH D . 
K 4 HOH 25 525 524 HOH HOH D . 
K 4 HOH 26 526 523 HOH HOH D . 
K 4 HOH 27 527 558 HOH HOH D . 
K 4 HOH 28 528 920 HOH HOH D . 
K 4 HOH 29 529 506 HOH HOH D . 
K 4 HOH 30 530 554 HOH HOH D . 
K 4 HOH 31 531 540 HOH HOH D . 
K 4 HOH 32 532 24  HOH HOH D . 
K 4 HOH 33 533 533 HOH HOH D . 
K 4 HOH 34 534 570 HOH HOH D . 
K 4 HOH 35 535 517 HOH HOH D . 
K 4 HOH 36 536 538 HOH HOH D . 
K 4 HOH 37 537 550 HOH HOH D . 
K 4 HOH 38 538 557 HOH HOH D . 
K 4 HOH 39 539 667 HOH HOH D . 
K 4 HOH 40 540 562 HOH HOH D . 
K 4 HOH 41 541 8   HOH HOH D . 
K 4 HOH 42 542 553 HOH HOH D . 
K 4 HOH 43 543 560 HOH HOH D . 
K 4 HOH 44 544 569 HOH HOH D . 
K 4 HOH 45 545 568 HOH HOH D . 
K 4 HOH 46 546 495 HOH HOH D . 
K 4 HOH 47 547 578 HOH HOH D . 
K 4 HOH 48 548 579 HOH HOH D . 
L 4 HOH 1  701 475 HOH HOH A . 
L 4 HOH 2  702 469 HOH HOH A . 
L 4 HOH 3  703 440 HOH HOH A . 
L 4 HOH 4  704 430 HOH HOH A . 
L 4 HOH 5  705 421 HOH HOH A . 
L 4 HOH 6  706 520 HOH HOH A . 
L 4 HOH 7  707 428 HOH HOH A . 
L 4 HOH 8  708 499 HOH HOH A . 
L 4 HOH 9  709 408 HOH HOH A . 
L 4 HOH 10 710 479 HOH HOH A . 
L 4 HOH 11 711 436 HOH HOH A . 
L 4 HOH 12 712 53  HOH HOH A . 
L 4 HOH 13 713 479 HOH HOH A . 
L 4 HOH 14 714 467 HOH HOH A . 
L 4 HOH 15 715 427 HOH HOH A . 
L 4 HOH 16 716 461 HOH HOH A . 
L 4 HOH 17 717 425 HOH HOH A . 
L 4 HOH 18 718 497 HOH HOH A . 
L 4 HOH 19 719 423 HOH HOH A . 
L 4 HOH 20 720 424 HOH HOH A . 
L 4 HOH 21 721 469 HOH HOH A . 
L 4 HOH 22 722 504 HOH HOH A . 
L 4 HOH 23 723 438 HOH HOH A . 
L 4 HOH 24 724 465 HOH HOH A . 
L 4 HOH 25 725 442 HOH HOH A . 
L 4 HOH 26 726 432 HOH HOH A . 
L 4 HOH 27 727 919 HOH HOH A . 
L 4 HOH 28 728 918 HOH HOH A . 
L 4 HOH 29 729 509 HOH HOH A . 
L 4 HOH 30 730 511 HOH HOH A . 
L 4 HOH 31 731 433 HOH HOH A . 
L 4 HOH 32 732 466 HOH HOH A . 
L 4 HOH 33 733 924 HOH HOH A . 
L 4 HOH 34 734 464 HOH HOH A . 
L 4 HOH 35 735 468 HOH HOH A . 
L 4 HOH 36 736 25  HOH HOH A . 
L 4 HOH 37 737 483 HOH HOH A . 
L 4 HOH 38 738 530 HOH HOH A . 
L 4 HOH 39 739 478 HOH HOH A . 
L 4 HOH 40 740 470 HOH HOH A . 
L 4 HOH 41 741 462 HOH HOH A . 
L 4 HOH 42 742 433 HOH HOH A . 
L 4 HOH 43 743 490 HOH HOH A . 
L 4 HOH 44 744 501 HOH HOH A . 
L 4 HOH 45 745 522 HOH HOH A . 
L 4 HOH 46 746 416 HOH HOH A . 
L 4 HOH 47 747 448 HOH HOH A . 
L 4 HOH 48 748 503 HOH HOH A . 
L 4 HOH 49 749 420 HOH HOH A . 
L 4 HOH 50 750 510 HOH HOH A . 
L 4 HOH 51 751 417 HOH HOH A . 
L 4 HOH 52 752 484 HOH HOH A . 
L 4 HOH 53 753 523 HOH HOH A . 
L 4 HOH 54 754 444 HOH HOH A . 
L 4 HOH 55 755 495 HOH HOH A . 
L 4 HOH 56 756 584 HOH HOH A . 
L 4 HOH 57 757 447 HOH HOH A . 
L 4 HOH 58 758 431 HOH HOH A . 
L 4 HOH 59 759 455 HOH HOH A . 
L 4 HOH 60 760 564 HOH HOH A . 
L 4 HOH 61 761 486 HOH HOH A . 
L 4 HOH 62 762 524 HOH HOH A . 
L 4 HOH 63 763 515 HOH HOH A . 
L 4 HOH 64 764 458 HOH HOH A . 
L 4 HOH 65 765 487 HOH HOH A . 
L 4 HOH 66 766 114 HOH HOH A . 
L 4 HOH 67 767 915 HOH HOH A . 
L 4 HOH 68 768 466 HOH HOH A . 
L 4 HOH 69 769 556 HOH HOH A . 
L 4 HOH 70 770 485 HOH HOH A . 
L 4 HOH 71 771 526 HOH HOH A . 
L 4 HOH 72 772 532 HOH HOH A . 
L 4 HOH 73 773 502 HOH HOH A . 
L 4 HOH 74 774 502 HOH HOH A . 
L 4 HOH 75 775 416 HOH HOH A . 
L 4 HOH 76 776 553 HOH HOH A . 
L 4 HOH 77 777 527 HOH HOH A . 
L 4 HOH 78 778 15  HOH HOH A . 
L 4 HOH 79 779 480 HOH HOH A . 
L 4 HOH 80 780 482 HOH HOH A . 
L 4 HOH 81 781 485 HOH HOH A . 
L 4 HOH 82 782 571 HOH HOH A . 
L 4 HOH 83 783 427 HOH HOH A . 
L 4 HOH 84 784 463 HOH HOH A . 
L 4 HOH 85 785 486 HOH HOH A . 
L 4 HOH 86 786 482 HOH HOH A . 
L 4 HOH 87 787 551 HOH HOH A . 
L 4 HOH 88 788 503 HOH HOH A . 
L 4 HOH 89 789 480 HOH HOH A . 
L 4 HOH 90 790 579 HOH HOH A . 
L 4 HOH 91 791 468 HOH HOH A . 
L 4 HOH 92 792 573 HOH HOH A . 
L 4 HOH 93 793 653 HOH HOH A . 
L 4 HOH 94 794 505 HOH HOH A . 
M 4 HOH 1  501 415 HOH HOH B . 
M 4 HOH 2  502 521 HOH HOH B . 
M 4 HOH 3  503 531 HOH HOH B . 
M 4 HOH 4  504 537 HOH HOH B . 
M 4 HOH 5  505 447 HOH HOH B . 
M 4 HOH 6  506 508 HOH HOH B . 
M 4 HOH 7  507 459 HOH HOH B . 
M 4 HOH 8  508 523 HOH HOH B . 
M 4 HOH 9  509 506 HOH HOH B . 
M 4 HOH 10 510 535 HOH HOH B . 
M 4 HOH 11 511 522 HOH HOH B . 
M 4 HOH 12 512 570 HOH HOH B . 
M 4 HOH 13 513 524 HOH HOH B . 
M 4 HOH 14 514 558 HOH HOH B . 
M 4 HOH 15 515 563 HOH HOH B . 
M 4 HOH 16 516 922 HOH HOH B . 
M 4 HOH 17 517 571 HOH HOH B . 
M 4 HOH 18 518 534 HOH HOH B . 
M 4 HOH 19 519 456 HOH HOH B . 
M 4 HOH 20 520 410 HOH HOH B . 
M 4 HOH 21 521 602 HOH HOH B . 
M 4 HOH 22 522 555 HOH HOH B . 
M 4 HOH 23 523 528 HOH HOH B . 
M 4 HOH 24 524 511 HOH HOH B . 
M 4 HOH 25 525 633 HOH HOH B . 
M 4 HOH 26 526 589 HOH HOH B . 
M 4 HOH 27 527 543 HOH HOH B . 
M 4 HOH 28 528 607 HOH HOH B . 
M 4 HOH 29 529 622 HOH HOH B . 
M 4 HOH 30 530 628 HOH HOH B . 
M 4 HOH 31 531 552 HOH HOH B . 
M 4 HOH 32 532 532 HOH HOH B . 
M 4 HOH 33 533 554 HOH HOH B . 
M 4 HOH 34 534 595 HOH HOH B . 
M 4 HOH 35 535 546 HOH HOH B . 
M 4 HOH 36 536 520 HOH HOH B . 
M 4 HOH 37 537 564 HOH HOH B . 
M 4 HOH 38 538 459 HOH HOH B . 
M 4 HOH 39 539 593 HOH HOH B . 
M 4 HOH 40 540 573 HOH HOH B . 
M 4 HOH 41 541 460 HOH HOH B . 
M 4 HOH 42 542 572 HOH HOH B . 
M 4 HOH 43 543 556 HOH HOH B . 
M 4 HOH 44 544 615 HOH HOH B . 
M 4 HOH 45 545 568 HOH HOH B . 
M 4 HOH 46 546 609 HOH HOH B . 
M 4 HOH 47 547 600 HOH HOH B . 
M 4 HOH 48 548 430 HOH HOH B . 
M 4 HOH 49 549 438 HOH HOH B . 
M 4 HOH 50 550 582 HOH HOH B . 
M 4 HOH 51 551 917 HOH HOH B . 
M 4 HOH 52 552 585 HOH HOH B . 
M 4 HOH 53 553 638 HOH HOH B . 
M 4 HOH 54 554 599 HOH HOH B . 
M 4 HOH 55 555 619 HOH HOH B . 
M 4 HOH 56 556 594 HOH HOH B . 
M 4 HOH 57 557 649 HOH HOH B . 
M 4 HOH 58 558 598 HOH HOH B . 
M 4 HOH 59 559 616 HOH HOH B . 
M 4 HOH 60 560 617 HOH HOH B . 
M 4 HOH 61 561 642 HOH HOH B . 
M 4 HOH 62 562 32  HOH HOH B . 
M 4 HOH 63 563 639 HOH HOH B . 
M 4 HOH 64 564 579 HOH HOH B . 
M 4 HOH 65 565 605 HOH HOH B . 
M 4 HOH 66 566 166 HOH HOH B . 
M 4 HOH 67 567 566 HOH HOH B . 
M 4 HOH 68 568 644 HOH HOH B . 
M 4 HOH 69 569 637 HOH HOH B . 
M 4 HOH 70 570 581 HOH HOH B . 
M 4 HOH 71 571 516 HOH HOH B . 
M 4 HOH 72 572 627 HOH HOH B . 
M 4 HOH 73 573 529 HOH HOH B . 
M 4 HOH 74 574 631 HOH HOH B . 
M 4 HOH 75 575 102 HOH HOH B . 
M 4 HOH 76 576 916 HOH HOH B . 
M 4 HOH 77 577 559 HOH HOH B . 
M 4 HOH 78 578 630 HOH HOH B . 
M 4 HOH 79 579 520 HOH HOH B . 
M 4 HOH 80 580 620 HOH HOH B . 
M 4 HOH 81 581 641 HOH HOH B . 
M 4 HOH 82 582 634 HOH HOH B . 
M 4 HOH 83 583 484 HOH HOH B . 
M 4 HOH 84 584 674 HOH HOH B . 
M 4 HOH 85 585 676 HOH HOH B . 
M 4 HOH 86 586 675 HOH HOH B . 
M 4 HOH 87 587 257 HOH HOH B . 
M 4 HOH 88 588 672 HOH HOH B . 
M 4 HOH 89 589 679 HOH HOH B . 
M 4 HOH 90 590 491 HOH HOH B . 
M 4 HOH 91 591 680 HOH HOH B . 
M 4 HOH 92 592 684 HOH HOH B . 
N 4 HOH 1  401 407 HOH HOH C . 
N 4 HOH 2  402 453 HOH HOH C . 
N 4 HOH 3  403 414 HOH HOH C . 
N 4 HOH 4  404 425 HOH HOH C . 
N 4 HOH 5  405 430 HOH HOH C . 
N 4 HOH 6  406 454 HOH HOH C . 
N 4 HOH 7  407 437 HOH HOH C . 
N 4 HOH 8  408 500 HOH HOH C . 
N 4 HOH 9  409 424 HOH HOH C . 
N 4 HOH 10 410 440 HOH HOH C . 
N 4 HOH 11 411 428 HOH HOH C . 
N 4 HOH 12 412 412 HOH HOH C . 
N 4 HOH 13 413 513 HOH HOH C . 
N 4 HOH 14 414 3   HOH HOH C . 
N 4 HOH 15 415 404 HOH HOH C . 
N 4 HOH 16 416 558 HOH HOH C . 
N 4 HOH 17 417 498 HOH HOH C . 
N 4 HOH 18 418 519 HOH HOH C . 
N 4 HOH 19 419 526 HOH HOH C . 
N 4 HOH 20 420 452 HOH HOH C . 
N 4 HOH 21 421 426 HOH HOH C . 
N 4 HOH 22 422 427 HOH HOH C . 
N 4 HOH 23 423 921 HOH HOH C . 
N 4 HOH 24 424 445 HOH HOH C . 
N 4 HOH 25 425 449 HOH HOH C . 
N 4 HOH 26 426 925 HOH HOH C . 
N 4 HOH 27 427 448 HOH HOH C . 
N 4 HOH 28 428 406 HOH HOH C . 
N 4 HOH 29 429 545 HOH HOH C . 
N 4 HOH 30 430 599 HOH HOH C . 
N 4 HOH 31 431 432 HOH HOH C . 
N 4 HOH 32 432 460 HOH HOH C . 
N 4 HOH 33 433 439 HOH HOH C . 
N 4 HOH 34 434 438 HOH HOH C . 
N 4 HOH 35 435 419 HOH HOH C . 
N 4 HOH 36 436 451 HOH HOH C . 
N 4 HOH 37 437 453 HOH HOH C . 
N 4 HOH 38 438 461 HOH HOH C . 
N 4 HOH 39 439 443 HOH HOH C . 
N 4 HOH 40 440 496 HOH HOH C . 
N 4 HOH 41 441 459 HOH HOH C . 
N 4 HOH 42 442 468 HOH HOH C . 
N 4 HOH 43 443 446 HOH HOH C . 
N 4 HOH 44 444 62  HOH HOH C . 
N 4 HOH 45 445 429 HOH HOH C . 
N 4 HOH 46 446 81  HOH HOH C . 
N 4 HOH 47 447 447 HOH HOH C . 
N 4 HOH 48 448 20  HOH HOH C . 
N 4 HOH 49 449 657 HOH HOH C . 
N 4 HOH 50 450 28  HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ET8 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.171 
_cell.length_a_esd                 ? 
_cell.length_b                     133.268 
_cell.length_b_esd                 ? 
_cell.length_c                     147.371 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ET8 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ET8 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.79 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.98 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ET8 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.31 
_reflns.d_resolution_low                               99.041 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     64500 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.14 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.31 
_reflns_shell.d_res_low                                     2.37 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.6 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4491 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.3 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.827 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.389 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -3.831 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            2.135 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            1.696 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               58.517 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.952 
_refine.correlation_coeff_Fo_to_Fc_free          0.946 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ET8 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.310 
_refine.ls_d_res_low                             99.041 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     64050 
_refine.ls_number_reflns_R_free                  3343 
_refine.ls_number_reflns_R_work                  60707 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.824 
_refine.ls_percent_reflns_R_free                 5.219 
_refine.ls_R_factor_all                          0.226 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2422 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2254 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.232 
_refine.ls_wR_factor_R_work                      0.219 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.341 
_refine.pdbx_overall_ESU_R_Free                  0.225 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9495 
_refine.pdbx_average_fsc_free                    0.9420 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.310 
_refine_hist.d_res_low                        99.041 
_refine_hist.number_atoms_solvent             284 
_refine_hist.number_atoms_total               9362 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9030 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         48 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.012  9377  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.646  1.848  12746 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.203  5.000  1133  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 25.438 5.000  47    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.556 10.000 1635  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.077 10.000 405   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.104  0.200  1437  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  7052  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.224  0.200  4389  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.318  0.200  6368  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.155  0.200  405   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.224  0.200  64    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.196  0.200  14    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 3.012  5.705  4523  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.962  10.256 5659  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.239  5.972  4854  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.659  10.870 7087  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.069  61.999 14240 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.310  2.370  4712 . 220 4120 92.1053  . 1.057 . . 1.054 . . . . . 1.305 . 20 . 0.773 0.775 1.116 
'X-RAY DIFFRACTION' 2.370  2.435  4620 . 252 4368 100.0000 . 0.357 . . 0.355 . . . . . 0.357 . 20 . 0.932 0.917 0.390 
'X-RAY DIFFRACTION' 2.435  2.505  4481 . 207 4274 100.0000 . 0.389 . . 0.389 . . . . . 0.390 . 20 . 0.936 0.928 0.381 
'X-RAY DIFFRACTION' 2.505  2.582  4384 . 224 4160 100.0000 . 0.410 . . 0.411 . . . . . 0.414 . 20 . 0.942 0.934 0.404 
'X-RAY DIFFRACTION' 2.582  2.667  4214 . 214 4000 100.0000 . 0.262 . . 0.261 . . . . . 0.252 . 20 . 0.955 0.945 0.290 
'X-RAY DIFFRACTION' 2.667  2.761  4098 . 226 3872 100.0000 . 0.260 . . 0.257 . . . . . 0.247 . 20 . 0.956 0.930 0.320 
'X-RAY DIFFRACTION' 2.761  2.865  3960 . 203 3757 100.0000 . 0.254 . . 0.254 . . . . . 0.244 . 20 . 0.958 0.956 0.260 
'X-RAY DIFFRACTION' 2.865  2.982  3821 . 212 3609 100.0000 . 0.252 . . 0.249 . . . . . 0.238 . 20 . 0.959 0.936 0.308 
'X-RAY DIFFRACTION' 2.982  3.114  3666 . 189 3477 100.0000 . 0.246 . . 0.245 . . . . . 0.237 . 20 . 0.963 0.960 0.253 
'X-RAY DIFFRACTION' 3.114  3.266  3502 . 176 3326 100.0000 . 0.238 . . 0.237 . . . . . 0.228 . 20 . 0.968 0.966 0.253 
'X-RAY DIFFRACTION' 3.266  3.442  3343 . 176 3167 100.0000 . 0.234 . . 0.231 . . . . . 0.224 . 20 . 0.971 0.958 0.281 
'X-RAY DIFFRACTION' 3.442  3.651  3159 . 178 2981 100.0000 . 0.213 . . 0.213 . . . . . 0.208 . 20 . 0.978 0.973 0.210 
'X-RAY DIFFRACTION' 3.651  3.903  3017 . 150 2613 91.5810  . 0.199 . . 0.198 . . . . . 0.195 . 20 . 0.980 0.976 0.217 
'X-RAY DIFFRACTION' 3.903  4.215  2774 . 137 2505 95.2415  . 0.176 . . 0.176 . . . . . 0.174 . 20 . 0.984 0.981 0.180 
'X-RAY DIFFRACTION' 4.215  4.616  2599 . 136 2463 100.0000 . 0.157 . . 0.156 . . . . . 0.156 . 20 . 0.987 0.985 0.161 
'X-RAY DIFFRACTION' 4.616  5.160  2330 . 100 2230 100.0000 . 0.158 . . 0.157 . . . . . 0.157 . 20 . 0.985 0.980 0.194 
'X-RAY DIFFRACTION' 5.160  5.955  2079 . 112 1967 100.0000 . 0.187 . . 0.185 . . . . . 0.185 . 20 . 0.982 0.977 0.215 
'X-RAY DIFFRACTION' 5.955  7.287  1795 . 101 1694 100.0000 . 0.215 . . 0.214 . . . . . 0.215 . 20 . 0.979 0.975 0.221 
'X-RAY DIFFRACTION' 7.287  10.278 1414 . 81  1333 100.0000 . 0.167 . . 0.168 . . . . . 0.179 . 20 . 0.986 0.990 0.146 
'X-RAY DIFFRACTION' 10.278 99.041 844  . 49  791  99.5261  . 0.221 . . 0.220 . . . . . 0.288 . 20 . 0.970 0.964 0.237 
# 
_struct.entry_id                     9ET8 
_struct.title                        'CDK2-cyclin A in complex with FragLite 5' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ET8 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CCNA2_BOVIN P30274 ? 1 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
2 UNP CDK2_HUMAN  P24941 ? 2 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ET8 D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
2 2 9ET8 A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
3 1 9ET8 B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
4 2 9ET8 C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ET8 GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 1  
1 9ET8 HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 2  
1 9ET8 HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 3  
1 9ET8 HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 4  
1 9ET8 HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 5  
1 9ET8 HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 6  
1 9ET8 HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 7  
2 9ET8 GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  8  
2 9ET8 PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  9  
2 9ET8 GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  10 
2 9ET8 SER A 4   ? UNP P24941 ? ? 'expression tag' 0   11 
3 9ET8 GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 12 
3 9ET8 HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 13 
3 9ET8 HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 14 
3 9ET8 HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 15 
3 9ET8 HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 16 
3 9ET8 HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 17 
3 9ET8 HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 18 
4 9ET8 GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  19 
4 9ET8 PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  20 
4 9ET8 GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  21 
4 9ET8 SER C 4   ? UNP P24941 ? ? 'expression tag' 0   22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3670  ? 
1 MORE         -16   ? 
1 'SSA (A^2)'  23270 ? 
2 'ABSA (A^2)' 3560  ? 
2 MORE         -16   ? 
2 'SSA (A^2)'  23660 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,H,I,J,K,N 
2 1 B,C,E,F,G,L,M 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 1   ? VAL A 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P2  AA2 TYR A 8   ? CYS A 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P3  AA3 GLY A 28  ? GLN A 33  ? GLY D 198 GLN D 203 5 ? 6  
HELX_P HELX_P4  AA4 THR A 37  ? TYR A 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P5  AA5 GLN A 58  ? LEU A 73  ? GLN D 228 LEU D 243 1 ? 16 
HELX_P HELX_P6  AA6 LEU A 79  ? GLU A 99  ? LEU D 249 GLU D 269 1 ? 21 
HELX_P HELX_P7  AA7 GLU A 104 ? ILE A 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P8  AA8 THR A 117 ? LEU A 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P9  AA9 THR A 140 ? LEU A 150 ? THR D 310 LEU D 320 1 ? 11 
HELX_P HELX_P10 AB1 ASN A 156 ? LEU A 171 ? ASN D 326 LEU D 341 1 ? 16 
HELX_P HELX_P11 AB2 ASP A 173 ? LEU A 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P12 AB3 LEU A 181 ? THR A 198 ? LEU D 351 THR D 368 1 ? 18 
HELX_P HELX_P13 AB4 PRO A 203 ? GLY A 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P14 AB5 LEU A 217 ? ALA A 231 ? LEU D 387 ALA D 401 1 ? 15 
HELX_P HELX_P15 AB6 PRO A 232 ? HIS A 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P16 AB7 GLN A 237 ? TYR A 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P17 AB8 LYS A 244 ? HIS A 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P18 AB9 GLY A 250 ? LEU A 254 ? GLY D 420 LEU D 424 5 ? 5  
HELX_P HELX_P19 AC1 SER B 4   ? GLU B 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P20 AC2 PRO B 49  ? LEU B 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P21 AC3 LEU B 91  ? ALA B 97  ? LEU A 87  ALA A 93  1 ? 7  
HELX_P HELX_P22 AC4 PRO B 104 ? HIS B 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P23 AC5 LYS B 133 ? GLN B 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P24 AC6 THR B 169 ? ARG B 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P25 AC7 ALA B 174 ? LEU B 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P26 AC8 THR B 186 ? ARG B 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P27 AC9 SER B 211 ? GLY B 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P28 AD1 GLY B 233 ? MET B 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P29 AD2 ASP B 251 ? VAL B 256 ? ASP A 247 VAL A 252 1 ? 6  
HELX_P HELX_P30 AD3 ASP B 260 ? LEU B 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P31 AD4 SER B 280 ? LEU B 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P32 AD5 ALA B 286 ? GLN B 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P33 AD6 GLY C 1   ? VAL C 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P34 AD7 TYR C 8   ? CYS C 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P35 AD8 THR C 37  ? TYR C 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P36 AD9 GLN C 58  ? MET C 76  ? GLN B 228 MET B 246 1 ? 19 
HELX_P HELX_P37 AE1 LEU C 79  ? GLY C 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P38 AE2 LYS C 82  ? GLU C 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P39 AE3 GLU C 104 ? ILE C 111 ? GLU B 274 ILE B 281 1 ? 8  
HELX_P HELX_P40 AE4 THR C 117 ? ALA C 133 ? THR B 287 ALA B 303 1 ? 17 
HELX_P HELX_P41 AE5 THR C 140 ? LEU C 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P42 AE6 ASN C 156 ? ASP C 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P43 AE7 ASP C 173 ? LEU C 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P44 AE8 LEU C 181 ? GLY C 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P45 AE9 PRO C 203 ? GLY C 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P46 AF1 THR C 213 ? ALA C 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P47 AF2 PRO C 232 ? HIS C 234 ? PRO B 402 HIS B 404 5 ? 3  
HELX_P HELX_P48 AF3 GLN C 237 ? TYR C 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P49 AF4 LYS C 244 ? HIS C 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P50 AF5 GLY C 250 ? LEU C 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P51 AF6 PRO D 49  ? LEU D 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P52 AF7 LEU D 91  ? SER D 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P53 AF8 PRO D 104 ? HIS D 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P54 AF9 LYS D 133 ? GLN D 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P55 AG1 ASP D 149 ? ALA D 153 ? ASP C 145 ALA C 149 5 ? 5  
HELX_P HELX_P56 AG2 THR D 169 ? ARG D 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P57 AG3 ALA D 174 ? LEU D 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P58 AG4 THR D 186 ? ARG D 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P59 AG5 SER D 211 ? GLY D 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P60 AG6 ASP D 251 ? VAL D 256 ? ASP C 247 VAL C 252 1 ? 6  
HELX_P HELX_P61 AG7 ASP D 260 ? LEU D 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P62 AG8 SER D 280 ? LEU D 285 ? SER C 276 LEU C 281 1 ? 6  
HELX_P HELX_P63 AG9 ALA D 286 ? GLN D 291 ? ALA C 282 GLN C 287 5 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? B TYR 163 C ? ? ? 1_555 B TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.326 ? ? 
covale2 covale both ? B TPO 164 C ? ? ? 1_555 B HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.338 ? ? 
covale3 covale both ? D TYR 163 C ? ? ? 1_555 D TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.346 ? ? 
covale4 covale both ? D TPO 164 C ? ? ? 1_555 D HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.344 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO B 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO D 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 153 A . ? GLN 323 D PRO 154 A ? PRO 324 D 1 6.68  
2 ASP 175 A . ? ASP 345 D PRO 176 A ? PRO 346 D 1 6.56  
3 VAL 158 B . ? VAL 154 A PRO 159 B ? PRO 155 A 1 -6.66 
4 GLN 153 C . ? GLN 323 B PRO 154 C ? PRO 324 B 1 -6.02 
5 ASP 175 C . ? ASP 345 B PRO 176 C ? PRO 346 B 1 10.13 
6 VAL 158 D . ? VAL 154 C PRO 159 D ? PRO 155 C 1 1.91  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 8   ? GLU B 16  ? PHE A 4   GLU A 12  
AA1 2 VAL B 21  ? ASN B 27  ? VAL A 17  ASN A 23  
AA1 3 VAL B 33  ? ARG B 40  ? VAL A 29  ARG A 36  
AA1 4 LYS B 79  ? GLU B 85  ? LYS A 75  GLU A 81  
AA1 5 LEU B 70  ? THR B 76  ? LEU A 66  THR A 72  
AA2 1 GLN B 89  ? ASP B 90  ? GLN A 85  ASP A 86  
AA2 2 LEU B 137 ? ILE B 139 ? LEU A 133 ILE A 135 
AA2 3 ILE B 145 ? LEU B 147 ? ILE A 141 LEU A 143 
AA3 1 VAL B 127 ? LEU B 128 ? VAL A 123 LEU A 124 
AA3 2 ARG B 154 ? ALA B 155 ? ARG A 150 ALA A 151 
AA4 1 PHE D 8   ? GLY D 15  ? PHE C 4   GLY C 11  
AA4 2 VAL D 21  ? ASN D 27  ? VAL C 17  ASN C 23  
AA4 3 VAL D 33  ? ARG D 40  ? VAL C 29  ARG C 36  
AA4 4 LYS D 79  ? GLU D 85  ? LYS C 75  GLU C 81  
AA4 5 LEU D 70  ? HIS D 75  ? LEU C 66  HIS C 71  
AA5 1 GLN D 89  ? ASP D 90  ? GLN C 85  ASP C 86  
AA5 2 LEU D 137 ? ILE D 139 ? LEU C 133 ILE C 135 
AA5 3 ILE D 145 ? LEU D 147 ? ILE C 141 LEU C 143 
AA6 1 VAL D 127 ? LEU D 128 ? VAL C 123 LEU C 124 
AA6 2 ARG D 154 ? ALA D 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU B 12  ? N GLU A 8   O LYS B 24  ? O LYS A 20  
AA1 2 3 N TYR B 23  ? N TYR A 19  O LEU B 36  ? O LEU A 32  
AA1 3 4 N ILE B 39  ? N ILE A 35  O LEU B 80  ? O LEU A 76  
AA1 4 5 O TYR B 81  ? O TYR A 77  N ILE B 74  ? N ILE A 70  
AA2 1 2 N GLN B 89  ? N GLN A 85  O ILE B 139 ? O ILE A 135 
AA2 2 3 N LEU B 138 ? N LEU A 134 O LYS B 146 ? O LYS A 142 
AA3 1 2 N LEU B 128 ? N LEU A 124 O ARG B 154 ? O ARG A 150 
AA4 1 2 N GLY D 15  ? N GLY C 11  O VAL D 22  ? O VAL C 18  
AA4 2 3 N TYR D 23  ? N TYR C 19  O LEU D 36  ? O LEU C 32  
AA4 3 4 N ILE D 39  ? N ILE C 35  O LEU D 80  ? O LEU C 76  
AA4 4 5 O VAL D 83  ? O VAL C 79  N LEU D 71  ? N LEU C 67  
AA5 1 2 N GLN D 89  ? N GLN C 85  O ILE D 139 ? O ILE C 135 
AA5 2 3 N LEU D 138 ? N LEU C 134 O LYS D 146 ? O LYS C 142 
AA6 1 2 N LEU D 128 ? N LEU C 124 O ARG D 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ET8 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             B 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             B 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             B 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                91.52 
_pdbx_validate_rmsd_angle.angle_target_value         102.60 
_pdbx_validate_rmsd_angle.angle_deviation            -11.08 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN D 323 ? ? -161.43 93.50   
2  1 HIS A 71  ? ? -107.50 59.39   
3  1 ASP A 92  ? ? -67.71  -70.25  
4  1 SER A 94  ? ? 75.81   158.85  
5  1 ARG A 126 ? ? 80.34   14.99   
6  1 ASP A 127 ? ? -160.45 45.49   
7  1 ASP A 145 ? ? 56.92   87.06   
8  1 VAL A 164 ? ? 86.37   127.57  
9  1 SER A 181 ? ? -143.93 -153.04 
10 1 LYS A 291 ? A 109.84  112.01  
11 1 LYS A 291 ? B 109.71  106.03  
12 1 TRP B 372 ? ? -33.28  115.59  
13 1 THR C 41  ? ? -131.11 -77.47  
14 1 SER C 94  ? ? -92.89  30.68   
15 1 ASP C 127 ? ? -153.66 44.93   
16 1 ASP C 145 ? ? 53.64   77.44   
17 1 VAL C 164 ? ? 74.52   129.52  
18 1 LEU C 175 ? ? -68.18  2.34    
19 1 PRO C 238 ? ? -36.65  -27.67  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG D 241 ? ? 0.236 'SIDE CHAIN' 
2  1 ARG A 150 ? ? 0.207 'SIDE CHAIN' 
3  1 ARG A 214 ? ? 0.080 'SIDE CHAIN' 
4  1 ARG A 245 ? ? 0.154 'SIDE CHAIN' 
5  1 ARG A 297 ? ? 0.274 'SIDE CHAIN' 
6  1 ARG B 187 ? ? 0.141 'SIDE CHAIN' 
7  1 ARG B 293 ? ? 0.272 'SIDE CHAIN' 
8  1 ARG C 36  ? ? 0.290 'SIDE CHAIN' 
9  1 ARG C 157 ? ? 0.135 'SIDE CHAIN' 
10 1 ARG C 245 ? ? 0.276 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 B TPO 164 A TPO 160 ? THR 'modified residue' 
2 D TPO 164 C TPO 160 ? THR 'modified residue' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       592 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.01 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 D HIS 433 ? A HIS 263 
2  1 Y 1 D HIS 434 ? A HIS 264 
3  1 Y 1 D HIS 435 ? A HIS 265 
4  1 Y 1 D HIS 436 ? A HIS 266 
5  1 Y 1 D HIS 437 ? A HIS 267 
6  1 Y 1 D HIS 438 ? A HIS 268 
7  1 Y 1 B HIS 433 ? C HIS 263 
8  1 Y 1 B HIS 434 ? C HIS 264 
9  1 Y 1 B HIS 435 ? C HIS 265 
10 1 Y 1 B HIS 436 ? C HIS 266 
11 1 Y 1 B HIS 437 ? C HIS 267 
12 1 Y 1 B HIS 438 ? C HIS 268 
13 1 Y 1 C GLY -3  ? D GLY 1   
14 1 Y 1 C PRO -2  ? D PRO 2   
15 1 Y 1 C GLY -1  ? D GLY 3   
16 1 Y 1 C ARG 297 ? D ARG 301 
17 1 Y 1 C LEU 298 ? D LEU 302 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
IIS C4   C Y N 161 
IIS C5   C Y N 162 
IIS N1   N N N 163 
IIS N2   N Y N 164 
IIS C3   C Y N 165 
IIS C1   C Y N 166 
IIS C2   C Y N 167 
IIS I1   I N N 168 
IIS H4   H N N 169 
IIS H5   H N N 170 
IIS H2   H N N 171 
IIS H1   H N N 172 
IIS H3   H N N 173 
ILE N    N N N 174 
ILE CA   C N S 175 
ILE C    C N N 176 
ILE O    O N N 177 
ILE CB   C N S 178 
ILE CG1  C N N 179 
ILE CG2  C N N 180 
ILE CD1  C N N 181 
ILE OXT  O N N 182 
ILE H    H N N 183 
ILE H2   H N N 184 
ILE HA   H N N 185 
ILE HB   H N N 186 
ILE HG12 H N N 187 
ILE HG13 H N N 188 
ILE HG21 H N N 189 
ILE HG22 H N N 190 
ILE HG23 H N N 191 
ILE HD11 H N N 192 
ILE HD12 H N N 193 
ILE HD13 H N N 194 
ILE HXT  H N N 195 
LEU N    N N N 196 
LEU CA   C N S 197 
LEU C    C N N 198 
LEU O    O N N 199 
LEU CB   C N N 200 
LEU CG   C N N 201 
LEU CD1  C N N 202 
LEU CD2  C N N 203 
LEU OXT  O N N 204 
LEU H    H N N 205 
LEU H2   H N N 206 
LEU HA   H N N 207 
LEU HB2  H N N 208 
LEU HB3  H N N 209 
LEU HG   H N N 210 
LEU HD11 H N N 211 
LEU HD12 H N N 212 
LEU HD13 H N N 213 
LEU HD21 H N N 214 
LEU HD22 H N N 215 
LEU HD23 H N N 216 
LEU HXT  H N N 217 
LYS N    N N N 218 
LYS CA   C N S 219 
LYS C    C N N 220 
LYS O    O N N 221 
LYS CB   C N N 222 
LYS CG   C N N 223 
LYS CD   C N N 224 
LYS CE   C N N 225 
LYS NZ   N N N 226 
LYS OXT  O N N 227 
LYS H    H N N 228 
LYS H2   H N N 229 
LYS HA   H N N 230 
LYS HB2  H N N 231 
LYS HB3  H N N 232 
LYS HG2  H N N 233 
LYS HG3  H N N 234 
LYS HD2  H N N 235 
LYS HD3  H N N 236 
LYS HE2  H N N 237 
LYS HE3  H N N 238 
LYS HZ1  H N N 239 
LYS HZ2  H N N 240 
LYS HZ3  H N N 241 
LYS HXT  H N N 242 
MET N    N N N 243 
MET CA   C N S 244 
MET C    C N N 245 
MET O    O N N 246 
MET CB   C N N 247 
MET CG   C N N 248 
MET SD   S N N 249 
MET CE   C N N 250 
MET OXT  O N N 251 
MET H    H N N 252 
MET H2   H N N 253 
MET HA   H N N 254 
MET HB2  H N N 255 
MET HB3  H N N 256 
MET HG2  H N N 257 
MET HG3  H N N 258 
MET HE1  H N N 259 
MET HE2  H N N 260 
MET HE3  H N N 261 
MET HXT  H N N 262 
PHE N    N N N 263 
PHE CA   C N S 264 
PHE C    C N N 265 
PHE O    O N N 266 
PHE CB   C N N 267 
PHE CG   C Y N 268 
PHE CD1  C Y N 269 
PHE CD2  C Y N 270 
PHE CE1  C Y N 271 
PHE CE2  C Y N 272 
PHE CZ   C Y N 273 
PHE OXT  O N N 274 
PHE H    H N N 275 
PHE H2   H N N 276 
PHE HA   H N N 277 
PHE HB2  H N N 278 
PHE HB3  H N N 279 
PHE HD1  H N N 280 
PHE HD2  H N N 281 
PHE HE1  H N N 282 
PHE HE2  H N N 283 
PHE HZ   H N N 284 
PHE HXT  H N N 285 
PRO N    N N N 286 
PRO CA   C N S 287 
PRO C    C N N 288 
PRO O    O N N 289 
PRO CB   C N N 290 
PRO CG   C N N 291 
PRO CD   C N N 292 
PRO OXT  O N N 293 
PRO H    H N N 294 
PRO HA   H N N 295 
PRO HB2  H N N 296 
PRO HB3  H N N 297 
PRO HG2  H N N 298 
PRO HG3  H N N 299 
PRO HD2  H N N 300 
PRO HD3  H N N 301 
PRO HXT  H N N 302 
SER N    N N N 303 
SER CA   C N S 304 
SER C    C N N 305 
SER O    O N N 306 
SER CB   C N N 307 
SER OG   O N N 308 
SER OXT  O N N 309 
SER H    H N N 310 
SER H2   H N N 311 
SER HA   H N N 312 
SER HB2  H N N 313 
SER HB3  H N N 314 
SER HG   H N N 315 
SER HXT  H N N 316 
THR N    N N N 317 
THR CA   C N S 318 
THR C    C N N 319 
THR O    O N N 320 
THR CB   C N R 321 
THR OG1  O N N 322 
THR CG2  C N N 323 
THR OXT  O N N 324 
THR H    H N N 325 
THR H2   H N N 326 
THR HA   H N N 327 
THR HB   H N N 328 
THR HG1  H N N 329 
THR HG21 H N N 330 
THR HG22 H N N 331 
THR HG23 H N N 332 
THR HXT  H N N 333 
TPO N    N N N 334 
TPO CA   C N S 335 
TPO CB   C N R 336 
TPO CG2  C N N 337 
TPO OG1  O N N 338 
TPO P    P N N 339 
TPO O1P  O N N 340 
TPO O2P  O N N 341 
TPO O3P  O N N 342 
TPO C    C N N 343 
TPO O    O N N 344 
TPO OXT  O N N 345 
TPO H    H N N 346 
TPO H2   H N N 347 
TPO HA   H N N 348 
TPO HB   H N N 349 
TPO HG21 H N N 350 
TPO HG22 H N N 351 
TPO HG23 H N N 352 
TPO HOP2 H N N 353 
TPO HOP3 H N N 354 
TPO HXT  H N N 355 
TRP N    N N N 356 
TRP CA   C N S 357 
TRP C    C N N 358 
TRP O    O N N 359 
TRP CB   C N N 360 
TRP CG   C Y N 361 
TRP CD1  C Y N 362 
TRP CD2  C Y N 363 
TRP NE1  N Y N 364 
TRP CE2  C Y N 365 
TRP CE3  C Y N 366 
TRP CZ2  C Y N 367 
TRP CZ3  C Y N 368 
TRP CH2  C Y N 369 
TRP OXT  O N N 370 
TRP H    H N N 371 
TRP H2   H N N 372 
TRP HA   H N N 373 
TRP HB2  H N N 374 
TRP HB3  H N N 375 
TRP HD1  H N N 376 
TRP HE1  H N N 377 
TRP HE3  H N N 378 
TRP HZ2  H N N 379 
TRP HZ3  H N N 380 
TRP HH2  H N N 381 
TRP HXT  H N N 382 
TYR N    N N N 383 
TYR CA   C N S 384 
TYR C    C N N 385 
TYR O    O N N 386 
TYR CB   C N N 387 
TYR CG   C Y N 388 
TYR CD1  C Y N 389 
TYR CD2  C Y N 390 
TYR CE1  C Y N 391 
TYR CE2  C Y N 392 
TYR CZ   C Y N 393 
TYR OH   O N N 394 
TYR OXT  O N N 395 
TYR H    H N N 396 
TYR H2   H N N 397 
TYR HA   H N N 398 
TYR HB2  H N N 399 
TYR HB3  H N N 400 
TYR HD1  H N N 401 
TYR HD2  H N N 402 
TYR HE1  H N N 403 
TYR HE2  H N N 404 
TYR HH   H N N 405 
TYR HXT  H N N 406 
VAL N    N N N 407 
VAL CA   C N S 408 
VAL C    C N N 409 
VAL O    O N N 410 
VAL CB   C N N 411 
VAL CG1  C N N 412 
VAL CG2  C N N 413 
VAL OXT  O N N 414 
VAL H    H N N 415 
VAL H2   H N N 416 
VAL HA   H N N 417 
VAL HB   H N N 418 
VAL HG11 H N N 419 
VAL HG12 H N N 420 
VAL HG13 H N N 421 
VAL HG21 H N N 422 
VAL HG22 H N N 423 
VAL HG23 H N N 424 
VAL HXT  H N N 425 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
IIS I1  C3   sing N N 152 
IIS C2  C3   doub Y N 153 
IIS C2  C1   sing Y N 154 
IIS C3  C4   sing Y N 155 
IIS N1  C1   sing N N 156 
IIS C1  N2   doub Y N 157 
IIS C4  C5   doub Y N 158 
IIS N2  C5   sing Y N 159 
IIS C4  H4   sing N N 160 
IIS C5  H5   sing N N 161 
IIS N1  H2   sing N N 162 
IIS N1  H1   sing N N 163 
IIS C2  H3   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PRO N   CA   sing N N 273 
PRO N   CD   sing N N 274 
PRO N   H    sing N N 275 
PRO CA  C    sing N N 276 
PRO CA  CB   sing N N 277 
PRO CA  HA   sing N N 278 
PRO C   O    doub N N 279 
PRO C   OXT  sing N N 280 
PRO CB  CG   sing N N 281 
PRO CB  HB2  sing N N 282 
PRO CB  HB3  sing N N 283 
PRO CG  CD   sing N N 284 
PRO CG  HG2  sing N N 285 
PRO CG  HG3  sing N N 286 
PRO CD  HD2  sing N N 287 
PRO CD  HD3  sing N N 288 
PRO OXT HXT  sing N N 289 
SER N   CA   sing N N 290 
SER N   H    sing N N 291 
SER N   H2   sing N N 292 
SER CA  C    sing N N 293 
SER CA  CB   sing N N 294 
SER CA  HA   sing N N 295 
SER C   O    doub N N 296 
SER C   OXT  sing N N 297 
SER CB  OG   sing N N 298 
SER CB  HB2  sing N N 299 
SER CB  HB3  sing N N 300 
SER OG  HG   sing N N 301 
SER OXT HXT  sing N N 302 
THR N   CA   sing N N 303 
THR N   H    sing N N 304 
THR N   H2   sing N N 305 
THR CA  C    sing N N 306 
THR CA  CB   sing N N 307 
THR CA  HA   sing N N 308 
THR C   O    doub N N 309 
THR C   OXT  sing N N 310 
THR CB  OG1  sing N N 311 
THR CB  CG2  sing N N 312 
THR CB  HB   sing N N 313 
THR OG1 HG1  sing N N 314 
THR CG2 HG21 sing N N 315 
THR CG2 HG22 sing N N 316 
THR CG2 HG23 sing N N 317 
THR OXT HXT  sing N N 318 
TPO N   CA   sing N N 319 
TPO N   H    sing N N 320 
TPO N   H2   sing N N 321 
TPO CA  CB   sing N N 322 
TPO CA  C    sing N N 323 
TPO CA  HA   sing N N 324 
TPO CB  CG2  sing N N 325 
TPO CB  OG1  sing N N 326 
TPO CB  HB   sing N N 327 
TPO CG2 HG21 sing N N 328 
TPO CG2 HG22 sing N N 329 
TPO CG2 HG23 sing N N 330 
TPO OG1 P    sing N N 331 
TPO P   O1P  doub N N 332 
TPO P   O2P  sing N N 333 
TPO P   O3P  sing N N 334 
TPO O2P HOP2 sing N N 335 
TPO O3P HOP3 sing N N 336 
TPO C   O    doub N N 337 
TPO C   OXT  sing N N 338 
TPO OXT HXT  sing N N 339 
TRP N   CA   sing N N 340 
TRP N   H    sing N N 341 
TRP N   H2   sing N N 342 
TRP CA  C    sing N N 343 
TRP CA  CB   sing N N 344 
TRP CA  HA   sing N N 345 
TRP C   O    doub N N 346 
TRP C   OXT  sing N N 347 
TRP CB  CG   sing N N 348 
TRP CB  HB2  sing N N 349 
TRP CB  HB3  sing N N 350 
TRP CG  CD1  doub Y N 351 
TRP CG  CD2  sing Y N 352 
TRP CD1 NE1  sing Y N 353 
TRP CD1 HD1  sing N N 354 
TRP CD2 CE2  doub Y N 355 
TRP CD2 CE3  sing Y N 356 
TRP NE1 CE2  sing Y N 357 
TRP NE1 HE1  sing N N 358 
TRP CE2 CZ2  sing Y N 359 
TRP CE3 CZ3  doub Y N 360 
TRP CE3 HE3  sing N N 361 
TRP CZ2 CH2  doub Y N 362 
TRP CZ2 HZ2  sing N N 363 
TRP CZ3 CH2  sing Y N 364 
TRP CZ3 HZ3  sing N N 365 
TRP CH2 HH2  sing N N 366 
TRP OXT HXT  sing N N 367 
TYR N   CA   sing N N 368 
TYR N   H    sing N N 369 
TYR N   H2   sing N N 370 
TYR CA  C    sing N N 371 
TYR CA  CB   sing N N 372 
TYR CA  HA   sing N N 373 
TYR C   O    doub N N 374 
TYR C   OXT  sing N N 375 
TYR CB  CG   sing N N 376 
TYR CB  HB2  sing N N 377 
TYR CB  HB3  sing N N 378 
TYR CG  CD1  doub Y N 379 
TYR CG  CD2  sing Y N 380 
TYR CD1 CE1  sing Y N 381 
TYR CD1 HD1  sing N N 382 
TYR CD2 CE2  doub Y N 383 
TYR CD2 HD2  sing N N 384 
TYR CE1 CZ   doub Y N 385 
TYR CE1 HE1  sing N N 386 
TYR CE2 CZ   sing Y N 387 
TYR CE2 HE2  sing N N 388 
TYR CZ  OH   sing N N 389 
TYR OH  HH   sing N N 390 
TYR OXT HXT  sing N N 391 
VAL N   CA   sing N N 392 
VAL N   H    sing N N 393 
VAL N   H2   sing N N 394 
VAL CA  C    sing N N 395 
VAL CA  CB   sing N N 396 
VAL CA  HA   sing N N 397 
VAL C   O    doub N N 398 
VAL C   OXT  sing N N 399 
VAL CB  CG1  sing N N 400 
VAL CB  CG2  sing N N 401 
VAL CB  HB   sing N N 402 
VAL CG1 HG11 sing N N 403 
VAL CG1 HG12 sing N N 404 
VAL CG1 HG13 sing N N 405 
VAL CG2 HG21 sing N N 406 
VAL CG2 HG22 sing N N 407 
VAL CG2 HG23 sing N N 408 
VAL OXT HXT  sing N N 409 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ET8 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013482 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007504 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006786 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201  10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
I 53 53 20.1470 4.3470  18.9947 0.3814  7.5137 27.7660 2.2735 66.8776 3.6514   
N 7  7  12.2220 0.0057  3.1346  9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870  5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P 15 15 6.4348  1.9067  4.1793  27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S 16 16 6.9054  1.4679  5.2035  22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 1   ? -65.219 0.943   30.834  1   74.56  ? 171 GLY D N   1 
ATOM   2    C CA  . GLY A 1 1   ? -64.829 2.365   30.894  1   76.22  ? 171 GLY D CA  1 
ATOM   3    C C   . GLY A 1 1   ? -63.311 2.487   30.747  1   73.94  ? 171 GLY D C   1 
ATOM   4    O O   . GLY A 1 1   ? -62.711 1.636   30.088  1   71.57  ? 171 GLY D O   1 
ATOM   5    N N   . VAL A 1 2   ? -62.718 3.52    31.377  1   69.87  ? 172 VAL D N   1 
ATOM   6    C CA  . VAL A 1 2   ? -61.393 3.984   31.001  1   65.95  ? 172 VAL D CA  1 
ATOM   7    C C   . VAL A 1 2   ? -60.373 2.965   31.496  1   63.92  ? 172 VAL D C   1 
ATOM   8    O O   . VAL A 1 2   ? -59.288 2.863   30.93   1   61.8   ? 172 VAL D O   1 
ATOM   9    C CB  . VAL A 1 2   ? -61.057 5.414   31.475  1   64.39  ? 172 VAL D CB  1 
ATOM   10   C CG1 . VAL A 1 2   ? -60.89  5.48    32.996  1   61.48  ? 172 VAL D CG1 1 
ATOM   11   C CG2 . VAL A 1 2   ? -59.85  6.002   30.736  1   59.93  ? 172 VAL D CG2 1 
ATOM   12   N N   . ASN A 1 3   ? -60.758 2.213   32.535  1   65.23  ? 173 ASN D N   1 
ATOM   13   C CA  . ASN A 1 3   ? -59.944 1.168   33.144  1   63.93  ? 173 ASN D CA  1 
ATOM   14   C C   . ASN A 1 3   ? -59.707 0.019   32.161  1   62.52  ? 173 ASN D C   1 
ATOM   15   O O   . ASN A 1 3   ? -58.837 -0.82   32.403  1   59.57  ? 173 ASN D O   1 
ATOM   16   C CB  . ASN A 1 3   ? -60.59  0.665   34.434  1   66.89  ? 173 ASN D CB  1 
ATOM   17   C CG  . ASN A 1 3   ? -60.794 1.777   35.434  1   68.92  ? 173 ASN D CG  1 
ATOM   18   O OD1 . ASN A 1 3   ? -60.091 2.791   35.361  1   69.63  ? 173 ASN D OD1 1 
ATOM   19   N ND2 . ASN A 1 3   ? -61.741 1.622   36.355  1   70.3   ? 173 ASN D ND2 1 
ATOM   20   N N   . GLU A 1 4   ? -60.493 -0.015  31.072  1   62.98  ? 174 GLU D N   1 
ATOM   21   C CA  . GLU A 1 4   ? -60.318 -0.974  29.995  1   64.21  ? 174 GLU D CA  1 
ATOM   22   C C   . GLU A 1 4   ? -59.865 -0.277  28.714  1   65.36  ? 174 GLU D C   1 
ATOM   23   O O   . GLU A 1 4   ? -59.81  -0.911  27.659  1   63.81  ? 174 GLU D O   1 
ATOM   24   C CB  . GLU A 1 4   ? -61.62  -1.716  29.724  1   67.73  ? 174 GLU D CB  1 
ATOM   25   C CG  . GLU A 1 4   ? -62.118 -2.493  30.936  1   71.78  ? 174 GLU D CG  1 
ATOM   26   C CD  . GLU A 1 4   ? -63.534 -2.976  30.744  1   78.28  ? 174 GLU D CD  1 
ATOM   27   O OE1 . GLU A 1 4   ? -64.106 -2.749  29.637  1   78.83  ? 174 GLU D OE1 1 
ATOM   28   O OE2 . GLU A 1 4   ? -64.033 -3.574  31.727  1   79.03  ? 174 GLU D OE2 1 
ATOM   29   N N   . VAL A 1 5   ? -59.524 1.02    28.822  1   66.52  ? 175 VAL D N   1 
ATOM   30   C CA  . VAL A 1 5   ? -58.811 1.78    27.795  1   64.23  ? 175 VAL D CA  1 
ATOM   31   C C   . VAL A 1 5   ? -59.377 1.421   26.419  1   64.73  ? 175 VAL D C   1 
ATOM   32   O O   . VAL A 1 5   ? -58.702 0.83    25.57   1   61.71  ? 175 VAL D O   1 
ATOM   33   C CB  . VAL A 1 5   ? -57.276 1.602   27.893  1   59.77  ? 175 VAL D CB  1 
ATOM   34   C CG1 . VAL A 1 5   ? -56.72  2.166   29.192  1   59.11  ? 175 VAL D CG1 1 
ATOM   35   C CG2 . VAL A 1 5   ? -56.827 0.157   27.763  1   56.12  ? 175 VAL D CG2 1 
ATOM   36   N N   . PRO A 1 6   ? -60.662 1.734   26.159  1   68.26  ? 176 PRO D N   1 
ATOM   37   C CA  . PRO A 1 6   ? -61.305 1.313   24.915  1   70.55  ? 176 PRO D CA  1 
ATOM   38   C C   . PRO A 1 6   ? -60.646 1.923   23.673  1   72.34  ? 176 PRO D C   1 
ATOM   39   O O   . PRO A 1 6   ? -60.548 1.257   22.64   1   74.14  ? 176 PRO D O   1 
ATOM   40   C CB  . PRO A 1 6   ? -62.787 1.692   25.074  1   71.78  ? 176 PRO D CB  1 
ATOM   41   C CG  . PRO A 1 6   ? -62.764 2.764   26.136  1   72.67  ? 176 PRO D CG  1 
ATOM   42   C CD  . PRO A 1 6   ? -61.567 2.479   27.045  1   71.1   ? 176 PRO D CD  1 
ATOM   43   N N   . ASP A 1 7   ? -60.16  3.169   23.77   1   70.32  ? 177 ASP D N   1 
ATOM   44   C CA  . ASP A 1 7   ? -59.531 3.776   22.611  1   69.03  ? 177 ASP D CA  1 
ATOM   45   C C   . ASP A 1 7   ? -58.179 3.129   22.316  1   65.85  ? 177 ASP D C   1 
ATOM   46   O O   . ASP A 1 7   ? -57.573 3.483   21.304  1   64.56  ? 177 ASP D O   1 
ATOM   47   C CB  . ASP A 1 7   ? -59.319 5.272   22.77   1   71.18  ? 177 ASP D CB  1 
ATOM   48   C CG  . ASP A 1 7   ? -60.516 6.158   22.47   1   74.58  ? 177 ASP D CG  1 
ATOM   49   O OD1 . ASP A 1 7   ? -61.142 5.929   21.425  1   80.86  ? 177 ASP D OD1 1 
ATOM   50   O OD2 . ASP A 1 7   ? -60.79  7.081   23.26   1   72.63  ? 177 ASP D OD2 1 
ATOM   51   N N   . TYR A 1 8   ? -57.716 2.191   23.171  1   63.34  ? 178 TYR D N   1 
ATOM   52   C CA  . TYR A 1 8   ? -56.351 1.669   23.076  1   61.68  ? 178 TYR D CA  1 
ATOM   53   C C   . TYR A 1 8   ? -56.24  0.145   23.129  1   64.41  ? 178 TYR D C   1 
ATOM   54   O O   . TYR A 1 8   ? -55.175 -0.368  22.783  1   65.97  ? 178 TYR D O   1 
ATOM   55   C CB  . TYR A 1 8   ? -55.402 2.269   24.122  1   55.63  ? 178 TYR D CB  1 
ATOM   56   C CG  . TYR A 1 8   ? -55.27  3.774   23.974  1   54.31  ? 178 TYR D CG  1 
ATOM   57   C CD1 . TYR A 1 8   ? -54.598 4.342   22.899  1   53.41  ? 178 TYR D CD1 1 
ATOM   58   C CD2 . TYR A 1 8   ? -55.89  4.626   24.882  1   54.79  ? 178 TYR D CD2 1 
ATOM   59   C CE1 . TYR A 1 8   ? -54.507 5.721   22.771  1   54.83  ? 178 TYR D CE1 1 
ATOM   60   C CE2 . TYR A 1 8   ? -55.809 6.005   24.758  1   54.64  ? 178 TYR D CE2 1 
ATOM   61   C CZ  . TYR A 1 8   ? -55.13  6.562   23.69   1   55     ? 178 TYR D CZ  1 
ATOM   62   O OH  . TYR A 1 8   ? -55.066 7.937   23.604  1   55.69  ? 178 TYR D OH  1 
ATOM   63   N N   . HIS A 1 9   ? -57.28  -0.586  23.567  1   68.69  ? 179 HIS D N   1 
ATOM   64   C CA  . HIS A 1 9   ? -57.155 -2.04   23.733  1   74.34  ? 179 HIS D CA  1 
ATOM   65   C C   . HIS A 1 9   ? -56.619 -2.716  22.461  1   71.65  ? 179 HIS D C   1 
ATOM   66   O O   . HIS A 1 9   ? -55.853 -3.67   22.552  1   64.3   ? 179 HIS D O   1 
ATOM   67   C CB  . HIS A 1 9   ? -58.421 -2.708  24.31   1   79.02  ? 179 HIS D CB  1 
ATOM   68   C CG  . HIS A 1 9   ? -59.559 -2.927  23.365  1   87.22  ? 179 HIS D CG  1 
ATOM   69   N ND1 . HIS A 1 9   ? -60.74  -2.209  23.424  1   98.87  ? 179 HIS D ND1 1 
ATOM   70   C CD2 . HIS A 1 9   ? -59.714 -3.795  22.349  1   95.08  ? 179 HIS D CD2 1 
ATOM   71   C CE1 . HIS A 1 9   ? -61.565 -2.615  22.463  1   97.42  ? 179 HIS D CE1 1 
ATOM   72   N NE2 . HIS A 1 9   ? -60.965 -3.587  21.801  1   97.17  ? 179 HIS D NE2 1 
ATOM   73   N N   . GLU A 1 10  ? -57.045 -2.226  21.286  1   73.59  ? 180 GLU D N   1 
ATOM   74   C CA  . GLU A 1 10  ? -56.76  -2.877  20.019  1   74.16  ? 180 GLU D CA  1 
ATOM   75   C C   . GLU A 1 10  ? -55.286 -2.673  19.684  1   70.25  ? 180 GLU D C   1 
ATOM   76   O O   . GLU A 1 10  ? -54.608 -3.647  19.355  1   70.14  ? 180 GLU D O   1 
ATOM   77   C CB  . GLU A 1 10  ? -57.656 -2.321  18.916  1   80.62  ? 180 GLU D CB  1 
ATOM   78   C CG  . GLU A 1 10  ? -57.938 -3.266  17.749  1   86.5   ? 180 GLU D CG  1 
ATOM   79   C CD  . GLU A 1 10  ? -58.665 -2.549  16.601  1   95.11  ? 180 GLU D CD  1 
ATOM   80   O OE1 . GLU A 1 10  ? -59.566 -1.711  16.86   1   96.39  ? 180 GLU D OE1 1 
ATOM   81   O OE2 . GLU A 1 10  ? -58.347 -2.815  15.421  1   93.75  ? 180 GLU D OE2 1 
ATOM   82   N N   . ASP A 1 11  ? -54.808 -1.418  19.77   1   66.04  ? 181 ASP D N   1 
ATOM   83   C CA  . ASP A 1 11  ? -53.416 -1.091  19.487  1   63.7   ? 181 ASP D CA  1 
ATOM   84   C C   . ASP A 1 11  ? -52.488 -1.769  20.491  1   60.59  ? 181 ASP D C   1 
ATOM   85   O O   . ASP A 1 11  ? -51.44  -2.259  20.091  1   63.23  ? 181 ASP D O   1 
ATOM   86   C CB  . ASP A 1 11  ? -53.133 0.397   19.552  1   65.08  ? 181 ASP D CB  1 
ATOM   87   C CG  . ASP A 1 11  ? -53.761 1.251   18.462  1   69.15  ? 181 ASP D CG  1 
ATOM   88   O OD1 . ASP A 1 11  ? -54.16  0.666   17.434  1   69.02  ? 181 ASP D OD1 1 
ATOM   89   O OD2 . ASP A 1 11  ? -53.863 2.495   18.67   1   70.42  ? 181 ASP D OD2 1 
ATOM   90   N N   . ILE A 1 12  ? -52.888 -1.797  21.772  1   56.62  ? 182 ILE D N   1 
ATOM   91   C CA  . ILE A 1 12  ? -52.122 -2.44   22.823  1   55.98  ? 182 ILE D CA  1 
ATOM   92   C C   . ILE A 1 12  ? -51.962 -3.927  22.526  1   56.79  ? 182 ILE D C   1 
ATOM   93   O O   . ILE A 1 12  ? -50.837 -4.426  22.569  1   57.73  ? 182 ILE D O   1 
ATOM   94   C CB  . ILE A 1 12  ? -52.7   -2.19   24.23   1   54.54  ? 182 ILE D CB  1 
ATOM   95   C CG1 . ILE A 1 12  ? -52.347 -0.808  24.746  1   53.38  ? 182 ILE D CG1 1 
ATOM   96   C CG2 . ILE A 1 12  ? -52.171 -3.234  25.198  1   50.68  ? 182 ILE D CG2 1 
ATOM   97   C CD1 . ILE A 1 12  ? -53.139 -0.383  25.967  1   53.95  ? 182 ILE D CD1 1 
ATOM   98   N N   . HIS A 1 13  ? -53.076 -4.614  22.228  1   56.92  ? 183 HIS D N   1 
ATOM   99   C CA  . HIS A 1 13  ? -53.096 -6.02   21.827  1   54.65  ? 183 HIS D CA  1 
ATOM   100  C C   . HIS A 1 13  ? -52.13  -6.275  20.661  1   54.97  ? 183 HIS D C   1 
ATOM   101  O O   . HIS A 1 13  ? -51.24  -7.112  20.774  1   56.59  ? 183 HIS D O   1 
ATOM   102  C CB  . HIS A 1 13  ? -54.532 -6.504  21.568  1   55.8   ? 183 HIS D CB  1 
ATOM   103  C CG  . HIS A 1 13  ? -54.563 -7.921  21.115  1   57.18  ? 183 HIS D CG  1 
ATOM   104  N ND1 . HIS A 1 13  ? -54.451 -8.957  22.023  1   57.3   ? 183 HIS D ND1 1 
ATOM   105  C CD2 . HIS A 1 13  ? -54.589 -8.485  19.905  1   57.45  ? 183 HIS D CD2 1 
ATOM   106  C CE1 . HIS A 1 13  ? -54.427 -10.109 21.387  1   55.71  ? 183 HIS D CE1 1 
ATOM   107  N NE2 . HIS A 1 13  ? -54.506 -9.843  20.102  1   58.29  ? 183 HIS D NE2 1 
ATOM   108  N N   . THR A 1 14  ? -52.262 -5.517  19.562  1   55.25  ? 184 THR D N   1 
ATOM   109  C CA  . THR A 1 14  ? -51.37  -5.634  18.413  1   57.5   ? 184 THR D CA  1 
ATOM   110  C C   . THR A 1 14  ? -49.898 -5.467  18.819  1   59.43  ? 184 THR D C   1 
ATOM   111  O O   . THR A 1 14  ? -49.033 -6.15   18.277  1   61.27  ? 184 THR D O   1 
ATOM   112  C CB  . THR A 1 14  ? -51.758 -4.61   17.345  1   59.96  ? 184 THR D CB  1 
ATOM   113  O OG1 . THR A 1 14  ? -53.111 -4.871  16.968  1   64.31  ? 184 THR D OG1 1 
ATOM   114  C CG2 . THR A 1 14  ? -50.847 -4.655  16.129  1   57.68  ? 184 THR D CG2 1 
ATOM   115  N N   . TYR A 1 15  ? -49.616 -4.531  19.741  1   56.65  ? 185 TYR D N   1 
ATOM   116  C CA  . TYR A 1 15  ? -48.264 -4.225  20.156  1   53.35  ? 185 TYR D CA  1 
ATOM   117  C C   . TYR A 1 15  ? -47.717 -5.407  20.946  1   52.31  ? 185 TYR D C   1 
ATOM   118  O O   . TYR A 1 15  ? -46.592 -5.828  20.683  1   53.17  ? 185 TYR D O   1 
ATOM   119  C CB  . TYR A 1 15  ? -48.194 -2.947  20.995  1   53.91  ? 185 TYR D CB  1 
ATOM   120  C CG  . TYR A 1 15  ? -46.785 -2.57   21.426  1   53.18  ? 185 TYR D CG  1 
ATOM   121  C CD1 . TYR A 1 15  ? -45.786 -2.382  20.472  1   55.11  ? 185 TYR D CD1 1 
ATOM   122  C CD2 . TYR A 1 15  ? -46.445 -2.442  22.775  1   51.69  ? 185 TYR D CD2 1 
ATOM   123  C CE1 . TYR A 1 15  ? -44.493 -2.048  20.83   1   55.71  ? 185 TYR D CE1 1 
ATOM   124  C CE2 . TYR A 1 15  ? -45.148 -2.12   23.149  1   52.96  ? 185 TYR D CE2 1 
ATOM   125  C CZ  . TYR A 1 15  ? -44.172 -1.927  22.175  1   57.01  ? 185 TYR D CZ  1 
ATOM   126  O OH  . TYR A 1 15  ? -42.872 -1.603  22.484  1   61.27  ? 185 TYR D OH  1 
ATOM   127  N N   . LEU A 1 16  ? -48.513 -5.953  21.883  1   50.3   ? 186 LEU D N   1 
ATOM   128  C CA  . LEU A 1 16  ? -48.054 -7.047  22.732  1   47.77  ? 186 LEU D CA  1 
ATOM   129  C C   . LEU A 1 16  ? -47.764 -8.27   21.861  1   49.44  ? 186 LEU D C   1 
ATOM   130  O O   . LEU A 1 16  ? -46.927 -9.089  22.193  1   47.26  ? 186 LEU D O   1 
ATOM   131  C CB  . LEU A 1 16  ? -49.098 -7.389  23.8    1   45.69  ? 186 LEU D CB  1 
ATOM   132  C CG  . LEU A 1 16  ? -49.47  -6.284  24.789  1   46.52  ? 186 LEU D CG  1 
ATOM   133  C CD1 . LEU A 1 16  ? -50.632 -6.751  25.657  1   46.67  ? 186 LEU D CD1 1 
ATOM   134  C CD2 . LEU A 1 16  ? -48.265 -5.833  25.654  1   44.46  ? 186 LEU D CD2 1 
ATOM   135  N N   . ARG A 1 17  ? -48.508 -8.418  20.758  1   53.59  ? 187 ARG D N   1 
ATOM   136  C CA  . ARG A 1 17  ? -48.336 -9.562  19.887  1   54.69  ? 187 ARG D CA  1 
ATOM   137  C C   . ARG A 1 17  ? -46.968 -9.483  19.233  1   56.58  ? 187 ARG D C   1 
ATOM   138  O O   . ARG A 1 17  ? -46.252 -10.48  19.138  1   60.64  ? 187 ARG D O   1 
ATOM   139  C CB  . ARG A 1 17  ? -49.466 -9.639  18.856  1   56.86  ? 187 ARG D CB  1 
ATOM   140  C CG  . ARG A 1 17  ? -50.772 -10.135 19.454  1   55.67  ? 187 ARG D CG  1 
ATOM   141  C CD  . ARG A 1 17  ? -50.763 -11.615 19.77   1   54.46  ? 187 ARG D CD  1 
ATOM   142  N NE  . ARG A 1 17  ? -50.544 -12.366 18.533  1   56.24  ? 187 ARG D NE  1 
ATOM   143  C CZ  . ARG A 1 17  ? -51.49  -12.892 17.763  1   57.69  ? 187 ARG D CZ  1 
ATOM   144  N NH1 . ARG A 1 17  ? -52.76  -12.828 18.129  1   58.01  ? 187 ARG D NH1 1 
ATOM   145  N NH2 . ARG A 1 17  ? -51.151 -13.466 16.626  1   56.62  ? 187 ARG D NH2 1 
ATOM   146  N N   . GLU A 1 18  ? -46.62  -8.274  18.796  1   56.38  ? 188 GLU D N   1 
ATOM   147  C CA  . GLU A 1 18  ? -45.318 -8.053  18.206  1   57.19  ? 188 GLU D CA  1 
ATOM   148  C C   . GLU A 1 18  ? -44.239 -8.235  19.274  1   54.87  ? 188 GLU D C   1 
ATOM   149  O O   . GLU A 1 18  ? -43.249 -8.909  19.031  1   53.99  ? 188 GLU D O   1 
ATOM   150  C CB  . GLU A 1 18  ? -45.466 -6.72   17.487  1   62.23  ? 188 GLU D CB  1 
ATOM   151  C CG  . GLU A 1 18  ? -44.166 -5.942  17.319  1   68.51  ? 188 GLU D CG  1 
ATOM   152  C CD  . GLU A 1 18  ? -44.5   -4.598  16.696  1   77.2   ? 188 GLU D CD  1 
ATOM   153  O OE1 . GLU A 1 18  ? -45.697 -4.349  16.311  1   76.56  ? 188 GLU D OE1 1 
ATOM   154  O OE2 . GLU A 1 18  ? -43.521 -3.813  16.622  1   76.59  ? 188 GLU D OE2 1 
ATOM   155  N N   . MET A 1 19  ? -44.505 -7.78   20.499  1   54.21  ? 189 MET D N   1 
ATOM   156  C CA  . MET A 1 19  ? -43.48  -7.752  21.529  1   53.09  ? 189 MET D CA  1 
ATOM   157  C C   . MET A 1 19  ? -43.2   -9.137  22.102  1   55.55  ? 189 MET D C   1 
ATOM   158  O O   . MET A 1 19  ? -42.055 -9.428  22.434  1   56.25  ? 189 MET D O   1 
ATOM   159  C CB  . MET A 1 19  ? -43.829 -6.771  22.644  1   50.89  ? 189 MET D CB  1 
ATOM   160  C CG  . MET A 1 19  ? -43.76  -5.326  22.188  1   59     ? 189 MET D CG  1 
ATOM   161  S SD  . MET A 1 19  ? -42.161 -4.79   21.531  1   63.99  ? 189 MET D SD  1 
ATOM   162  C CE  . MET A 1 19  ? -41.1   -5.225  22.931  1   69.44  ? 189 MET D CE  1 
ATOM   163  N N   . GLU A 1 20  ? -44.229 -9.986  22.226  1   53.91  ? 190 GLU D N   1 
ATOM   164  C CA  . GLU A 1 20  ? -44.045 -11.331 22.757  1   50.57  ? 190 GLU D CA  1 
ATOM   165  C C   . GLU A 1 20  ? -43.204 -12.188 21.811  1   53.15  ? 190 GLU D C   1 
ATOM   166  O O   . GLU A 1 20  ? -42.649 -13.198 22.243  1   54.29  ? 190 GLU D O   1 
ATOM   167  C CB  . GLU A 1 20  ? -45.355 -12.089 22.996  1   51.72  ? 190 GLU D CB  1 
ATOM   168  C CG  . GLU A 1 20  ? -46.198 -12.338 21.74   1   50     ? 190 GLU D CG  1 
ATOM   169  C CD  . GLU A 1 20  ? -47.362 -13.307 21.956  1   52.93  ? 190 GLU D CD  1 
ATOM   170  O OE1 . GLU A 1 20  ? -47.504 -13.913 23.045  1   49.87  ? 190 GLU D OE1 1 
ATOM   171  O OE2 . GLU A 1 20  ? -48.142 -13.495 20.992  1   54.74  ? 190 GLU D OE2 1 
ATOM   172  N N   . VAL A 1 21  ? -43.179 -11.836 20.518  1   52.41  ? 191 VAL D N   1 
ATOM   173  C CA  . VAL A 1 21  ? -42.259 -12.461 19.587  1   52.98  ? 191 VAL D CA  1 
ATOM   174  C C   . VAL A 1 21  ? -40.833 -12.011 19.926  1   56.96  ? 191 VAL D C   1 
ATOM   175  O O   . VAL A 1 21  ? -39.936 -12.838 20.052  1   58.23  ? 191 VAL D O   1 
ATOM   176  C CB  . VAL A 1 21  ? -42.641 -12.171 18.12   1   54.86  ? 191 VAL D CB  1 
ATOM   177  C CG1 . VAL A 1 21  ? -41.51  -12.517 17.136  1   52.28  ? 191 VAL D CG1 1 
ATOM   178  C CG2 . VAL A 1 21  ? -43.946 -12.876 17.739  1   53.19  ? 191 VAL D CG2 1 
ATOM   179  N N   . LYS A 1 22  ? -40.626 -10.703 20.099  1   59.55  ? 192 LYS D N   1 
ATOM   180  C CA  . LYS A 1 22  ? -39.314 -10.181 20.474  1   64.24  ? 192 LYS D CA  1 
ATOM   181  C C   . LYS A 1 22  ? -38.758 -10.825 21.752  1   55.58  ? 192 LYS D C   1 
ATOM   182  O O   . LYS A 1 22  ? -37.605 -11.198 21.785  1   54.64  ? 192 LYS D O   1 
ATOM   183  C CB  . LYS A 1 22  ? -39.306 -8.651  20.538  1   75.23  ? 192 LYS D CB  1 
ATOM   184  C CG  . LYS A 1 22  ? -38.415 -8.068  21.649  1   91.54  ? 192 LYS D CG  1 
ATOM   185  C CD  . LYS A 1 22  ? -37.853 -6.668  21.421  1   101.09 ? 192 LYS D CD  1 
ATOM   186  C CE  . LYS A 1 22  ? -36.581 -6.684  20.614  1   104.4  ? 192 LYS D CE  1 
ATOM   187  N NZ  . LYS A 1 22  ? -35.944 -5.368  20.52   1   114.81 ? 192 LYS D NZ  1 
ATOM   188  N N   . CYS A 1 23  ? -39.569 -10.959 22.802  1   53.51  ? 193 CYS D N   1 
ATOM   189  C CA  . CYS A 1 23  ? -39.102 -11.446 24.094  1   54.04  ? 193 CYS D CA  1 
ATOM   190  C C   . CYS A 1 23  ? -39.224 -12.961 24.226  1   54.88  ? 193 CYS D C   1 
ATOM   191  O O   . CYS A 1 23  ? -39.296 -13.471 25.346  1   58.92  ? 193 CYS D O   1 
ATOM   192  C CB  . CYS A 1 23  ? -39.93  -10.866 25.24   1   52.33  ? 193 CYS D CB  1 
ATOM   193  S SG  . CYS A 1 23  ? -39.897 -9.058  25.222  1   58.52  ? 193 CYS D SG  1 
ATOM   194  N N   . LYS A 1 24  ? -39.258 -13.68  23.104  1   56.25  ? 194 LYS D N   1 
ATOM   195  C CA  . LYS A 1 24  ? -39.48  -15.112 23.18   1   57.04  ? 194 LYS D CA  1 
ATOM   196  C C   . LYS A 1 24  ? -38.144 -15.796 23.442  1   57.09  ? 194 LYS D C   1 
ATOM   197  O O   . LYS A 1 24  ? -37.191 -15.549 22.717  1   55.2   ? 194 LYS D O   1 
ATOM   198  C CB  . LYS A 1 24  ? -40.066 -15.649 21.871  1   57.4   ? 194 LYS D CB  1 
ATOM   199  C CG  . LYS A 1 24  ? -40.593 -17.075 21.968  1   60.15  ? 194 LYS D CG  1 
ATOM   200  C CD  . LYS A 1 24  ? -40.756 -17.704 20.592  1   64.47  ? 194 LYS D CD  1 
ATOM   201  C CE  . LYS A 1 24  ? -41.449 -19.04  20.618  1   68.76  ? 194 LYS D CE  1 
ATOM   202  N NZ  . LYS A 1 24  ? -41.526 -19.556 19.245  1   74.46  ? 194 LYS D NZ  1 
ATOM   203  N N   . PRO A 1 25  ? -38.034 -16.656 24.484  1   59.79  ? 195 PRO D N   1 
ATOM   204  C CA  . PRO A 1 25  ? -36.803 -17.417 24.723  1   56.65  ? 195 PRO D CA  1 
ATOM   205  C C   . PRO A 1 25  ? -36.562 -18.338 23.539  1   56.45  ? 195 PRO D C   1 
ATOM   206  O O   . PRO A 1 25  ? -37.494 -18.603 22.796  1   58.27  ? 195 PRO D O   1 
ATOM   207  C CB  . PRO A 1 25  ? -37.074 -18.219 26.001  1   56.2   ? 195 PRO D CB  1 
ATOM   208  C CG  . PRO A 1 25  ? -38.308 -17.567 26.634  1   57.73  ? 195 PRO D CG  1 
ATOM   209  C CD  . PRO A 1 25  ? -39.089 -16.928 25.49   1   57.54  ? 195 PRO D CD  1 
ATOM   210  N N   . LYS A 1 26  ? -35.321 -18.828 23.392  1   57.03  ? 196 LYS D N   1 
ATOM   211  C CA  . LYS A 1 26  ? -34.998 -19.809 22.37   1   60.19  ? 196 LYS D CA  1 
ATOM   212  C C   . LYS A 1 26  ? -35.57  -21.184 22.733  1   61.09  ? 196 LYS D C   1 
ATOM   213  O O   . LYS A 1 26  ? -35.229 -21.752 23.776  1   60.45  ? 196 LYS D O   1 
ATOM   214  C CB  . LYS A 1 26  ? -33.489 -19.868 22.13   1   61.33  ? 196 LYS D CB  1 
ATOM   215  C CG  . LYS A 1 26  ? -32.849 -18.648 21.466  1   71.8   ? 196 LYS D CG  1 
ATOM   216  C CD  . LYS A 1 26  ? -31.473 -18.968 20.87   1   81.38  ? 196 LYS D CD  1 
ATOM   217  C CE  . LYS A 1 26  ? -30.703 -20.012 21.655  1   85.65  ? 196 LYS D CE  1 
ATOM   218  N NZ  . LYS A 1 26  ? -29.322 -20.251 21.226  1   97.44  ? 196 LYS D NZ  1 
ATOM   219  N N   . VAL A 1 27  ? -36.389 -21.73  21.82   1   61.31  ? 197 VAL D N   1 
ATOM   220  C CA  . VAL A 1 27  ? -37.13  -22.969 22.004  1   62.13  ? 197 VAL D CA  1 
ATOM   221  C C   . VAL A 1 27  ? -36.217 -24.088 22.498  1   61.62  ? 197 VAL D C   1 
ATOM   222  O O   . VAL A 1 27  ? -36.626 -24.883 23.361  1   64.97  ? 197 VAL D O   1 
ATOM   223  C CB  . VAL A 1 27  ? -37.877 -23.428 20.737  1   64.93  ? 197 VAL D CB  1 
ATOM   224  C CG1 . VAL A 1 27  ? -38.497 -24.802 20.925  1   66.63  ? 197 VAL D CG1 1 
ATOM   225  C CG2 . VAL A 1 27  ? -38.958 -22.443 20.311  1   65.72  ? 197 VAL D CG2 1 
ATOM   226  N N   . GLY A 1 28  ? -35.015 -24.191 21.921  1   58     ? 198 GLY D N   1 
ATOM   227  C CA  . GLY A 1 28  ? -34.204 -25.363 22.217  1   62.46  ? 198 GLY D CA  1 
ATOM   228  C C   . GLY A 1 28  ? -33.05  -25.111 23.196  1   67.21  ? 198 GLY D C   1 
ATOM   229  O O   . GLY A 1 28  ? -32.045 -25.825 23.136  1   69.11  ? 198 GLY D O   1 
ATOM   230  N N   . TYR A 1 29  ? -33.196 -24.146 24.123  1   60.28  ? 199 TYR D N   1 
ATOM   231  C CA  . TYR A 1 29  ? -32.014 -23.648 24.81   1   57.99  ? 199 TYR D CA  1 
ATOM   232  C C   . TYR A 1 29  ? -31.452 -24.701 25.76   1   58.92  ? 199 TYR D C   1 
ATOM   233  O O   . TYR A 1 29  ? -30.245 -24.714 26.049  1   59.35  ? 199 TYR D O   1 
ATOM   234  C CB  . TYR A 1 29  ? -32.217 -22.296 25.498  1   54.31  ? 199 TYR D CB  1 
ATOM   235  C CG  . TYR A 1 29  ? -32.896 -22.286 26.86   1   51.65  ? 199 TYR D CG  1 
ATOM   236  C CD1 . TYR A 1 29  ? -32.245 -22.751 28.006  1   52.22  ? 199 TYR D CD1 1 
ATOM   237  C CD2 . TYR A 1 29  ? -34.158 -21.734 27.02   1   49.1   ? 199 TYR D CD2 1 
ATOM   238  C CE1 . TYR A 1 29  ? -32.859 -22.71  29.252  1   51.51  ? 199 TYR D CE1 1 
ATOM   239  C CE2 . TYR A 1 29  ? -34.777 -21.679 28.259  1   47.41  ? 199 TYR D CE2 1 
ATOM   240  C CZ  . TYR A 1 29  ? -34.13  -22.168 29.373  1   49.85  ? 199 TYR D CZ  1 
ATOM   241  O OH  . TYR A 1 29  ? -34.76  -22.074 30.573  1   50.79  ? 199 TYR D OH  1 
ATOM   242  N N   . MET A 1 30  ? -32.334 -25.576 26.245  1   58.65  ? 200 MET D N   1 
ATOM   243  C CA  . MET A 1 30  ? -31.953 -26.446 27.342  1   60.88  ? 200 MET D CA  1 
ATOM   244  C C   . MET A 1 30  ? -30.951 -27.504 26.853  1   66.37  ? 200 MET D C   1 
ATOM   245  O O   . MET A 1 30  ? -30.065 -27.943 27.605  1   63.34  ? 200 MET D O   1 
ATOM   246  C CB  . MET A 1 30  ? -33.205 -27.021 28.007  1   62.28  ? 200 MET D CB  1 
ATOM   247  C CG  . MET A 1 30  ? -32.915 -27.596 29.36   1   63.97  ? 200 MET D CG  1 
ATOM   248  S SD  . MET A 1 30  ? -32.228 -26.295 30.398  1   68.15  ? 200 MET D SD  1 
ATOM   249  C CE  . MET A 1 30  ? -33.771 -25.761 31.146  1   68.45  ? 200 MET D CE  1 
ATOM   250  N N   . LYS A 1 31  ? -31.111 -27.923 25.587  1   65.61  ? 201 LYS D N   1 
ATOM   251  C CA  . LYS A 1 31  ? -30.196 -28.863 24.974  1   67.49  ? 201 LYS D CA  1 
ATOM   252  C C   . LYS A 1 31  ? -28.813 -28.243 24.84   1   66.86  ? 201 LYS D C   1 
ATOM   253  O O   . LYS A 1 31  ? -27.851 -28.988 24.728  1   71.95  ? 201 LYS D O   1 
ATOM   254  C CB  . LYS A 1 31  ? -30.674 -29.264 23.576  1   73.78  ? 201 LYS D CB  1 
ATOM   255  C CG  . LYS A 1 31  ? -31.76  -30.322 23.506  1   82.31  ? 201 LYS D CG  1 
ATOM   256  C CD  . LYS A 1 31  ? -32.977 -29.879 22.695  1   92.76  ? 201 LYS D CD  1 
ATOM   257  C CE  . LYS A 1 31  ? -32.797 -29.493 21.245  1   94.87  ? 201 LYS D CE  1 
ATOM   258  N NZ  . LYS A 1 31  ? -34.075 -29.347 20.537  1   89.41  ? 201 LYS D NZ  1 
ATOM   259  N N   . LYS A 1 32  ? -28.718 -26.903 24.835  1   63.8   ? 202 LYS D N   1 
ATOM   260  C CA  . LYS A 1 32  ? -27.461 -26.202 24.599  1   65.13  ? 202 LYS D CA  1 
ATOM   261  C C   . LYS A 1 32  ? -26.766 -25.807 25.904  1   62.44  ? 202 LYS D C   1 
ATOM   262  O O   . LYS A 1 32  ? -25.671 -25.233 25.873  1   60.9   ? 202 LYS D O   1 
ATOM   263  C CB  . LYS A 1 32  ? -27.697 -24.972 23.717  1   72.35  ? 202 LYS D CB  1 
ATOM   264  C CG  . LYS A 1 32  ? -28.19  -25.27  22.295  1   80.52  ? 202 LYS D CG  1 
ATOM   265  C CD  . LYS A 1 32  ? -28.679 -24.024 21.557  1   89.22  ? 202 LYS D CD  1 
ATOM   266  C CE  . LYS A 1 32  ? -29.42  -24.297 20.269  1   96.91  ? 202 LYS D CE  1 
ATOM   267  N NZ  . LYS A 1 32  ? -30.036 -23.079 19.729  1   94.63  ? 202 LYS D NZ  1 
ATOM   268  N N   . GLN A 1 33  ? -27.436 -26.091 27.037  1   63.21  ? 203 GLN D N   1 
ATOM   269  C CA  . GLN A 1 33  ? -26.939 -25.844 28.39   1   58.89  ? 203 GLN D CA  1 
ATOM   270  C C   . GLN A 1 33  ? -26.315 -27.129 28.935  1   60.87  ? 203 GLN D C   1 
ATOM   271  O O   . GLN A 1 33  ? -27.032 -28.053 29.332  1   62.19  ? 203 GLN D O   1 
ATOM   272  C CB  . GLN A 1 33  ? -28.069 -25.441 29.336  1   53.81  ? 203 GLN D CB  1 
ATOM   273  C CG  . GLN A 1 33  ? -28.627 -24.048 29.098  1   56.22  ? 203 GLN D CG  1 
ATOM   274  C CD  . GLN A 1 33  ? -27.753 -22.969 29.702  1   55.77  ? 203 GLN D CD  1 
ATOM   275  O OE1 . GLN A 1 33  ? -26.774 -23.281 30.389  1   54.03  ? 203 GLN D OE1 1 
ATOM   276  N NE2 . GLN A 1 33  ? -28.073 -21.707 29.422  1   49.62  ? 203 GLN D NE2 1 
ATOM   277  N N   . PRO A 1 34  ? -24.968 -27.232 28.99   1   60.81  ? 204 PRO D N   1 
ATOM   278  C CA  . PRO A 1 34  ? -24.324 -28.486 29.388  1   62.04  ? 204 PRO D CA  1 
ATOM   279  C C   . PRO A 1 34  ? -24.675 -28.991 30.791  1   62.32  ? 204 PRO D C   1 
ATOM   280  O O   . PRO A 1 34  ? -24.676 -30.195 31.02   1   67.84  ? 204 PRO D O   1 
ATOM   281  C CB  . PRO A 1 34  ? -22.814 -28.224 29.21   1   61.74  ? 204 PRO D CB  1 
ATOM   282  C CG  . PRO A 1 34  ? -22.745 -26.928 28.425  1   62.83  ? 204 PRO D CG  1 
ATOM   283  C CD  . PRO A 1 34  ? -24.007 -26.145 28.744  1   60.66  ? 204 PRO D CD  1 
ATOM   284  N N   . ASP A 1 35  ? -25.021 -28.092 31.715  1   60.21  ? 205 ASP D N   1 
ATOM   285  C CA  . ASP A 1 35  ? -25.105 -28.487 33.108  1   63.32  ? 205 ASP D CA  1 
ATOM   286  C C   . ASP A 1 35  ? -26.509 -28.327 33.7    1   63.89  ? 205 ASP D C   1 
ATOM   287  O O   . ASP A 1 35  ? -26.75  -28.765 34.822  1   70.23  ? 205 ASP D O   1 
ATOM   288  C CB  . ASP A 1 35  ? -24.005 -27.832 33.929  1   66.14  ? 205 ASP D CB  1 
ATOM   289  C CG  . ASP A 1 35  ? -23.829 -28.402 35.33   1   75.84  ? 205 ASP D CG  1 
ATOM   290  O OD1 . ASP A 1 35  ? -23.877 -29.655 35.438  1   81.31  ? 205 ASP D OD1 1 
ATOM   291  O OD2 . ASP A 1 35  ? -23.676 -27.602 36.3    1   70.84  ? 205 ASP D OD2 1 
ATOM   292  N N   . ILE A 1 36  ? -27.442 -27.688 32.992  1   59.8   ? 206 ILE D N   1 
ATOM   293  C CA  . ILE A 1 36  ? -28.77  -27.543 33.561  1   58.3   ? 206 ILE D CA  1 
ATOM   294  C C   . ILE A 1 36  ? -29.802 -28.243 32.672  1   59.79  ? 206 ILE D C   1 
ATOM   295  O O   . ILE A 1 36  ? -29.528 -28.496 31.501  1   59.93  ? 206 ILE D O   1 
ATOM   296  C CB  . ILE A 1 36  ? -29.093 -26.072 33.903  1   58.37  ? 206 ILE D CB  1 
ATOM   297  C CG1 . ILE A 1 36  ? -28.821 -25.144 32.772  1   57.16  ? 206 ILE D CG1 1 
ATOM   298  C CG2 . ILE A 1 36  ? -28.323 -25.603 35.144  1   59.81  ? 206 ILE D CG2 1 
ATOM   299  C CD1 . ILE A 1 36  ? -29.123 -23.702 33.121  1   54.01  ? 206 ILE D CD1 1 
ATOM   300  N N   . THR A 1 37  ? -30.954 -28.62  33.259  1   58.72  ? 207 THR D N   1 
ATOM   301  C CA  . THR A 1 37  ? -31.98  -29.456 32.627  1   58.24  ? 207 THR D CA  1 
ATOM   302  C C   . THR A 1 37  ? -33.375 -28.879 32.869  1   57.75  ? 207 THR D C   1 
ATOM   303  O O   . THR A 1 37  ? -33.567 -28.041 33.75   1   57.69  ? 207 THR D O   1 
ATOM   304  C CB  . THR A 1 37  ? -31.933 -30.895 33.154  1   59.83  ? 207 THR D CB  1 
ATOM   305  O OG1 . THR A 1 37  ? -32.052 -30.846 34.577  1   59.54  ? 207 THR D OG1 1 
ATOM   306  C CG2 . THR A 1 37  ? -30.691 -31.649 32.711  1   57.65  ? 207 THR D CG2 1 
ATOM   307  N N   . ASN A 1 38  ? -34.361 -29.374 32.107  1   59.93  ? 208 ASN D N   1 
ATOM   308  C CA  . ASN A 1 38  ? -35.745 -28.934 32.224  1   60.24  ? 208 ASN D CA  1 
ATOM   309  C C   . ASN A 1 38  ? -36.241 -29.216 33.64   1   60.53  ? 208 ASN D C   1 
ATOM   310  O O   . ASN A 1 38  ? -37.047 -28.457 34.187  1   59.31  ? 208 ASN D O   1 
ATOM   311  C CB  . ASN A 1 38  ? -36.671 -29.622 31.222  1   64.17  ? 208 ASN D CB  1 
ATOM   312  C CG  . ASN A 1 38  ? -36.42  -29.281 29.767  1   63.12  ? 208 ASN D CG  1 
ATOM   313  O OD1 . ASN A 1 38  ? -36.212 -28.116 29.411  1   63.04  ? 208 ASN D OD1 1 
ATOM   314  N ND2 . ASN A 1 38  ? -36.477 -30.292 28.911  1   61.67  ? 208 ASN D ND2 1 
ATOM   315  N N   . SER A 1 39  ? -35.748 -30.329 34.197  1   61.9   ? 209 SER D N   1 
ATOM   316  C CA  . SER A 1 39  ? -36.038 -30.782 35.552  1   62.63  ? 209 SER D CA  1 
ATOM   317  C C   . SER A 1 39  ? -35.607 -29.725 36.567  1   61.92  ? 209 SER D C   1 
ATOM   318  O O   . SER A 1 39  ? -36.352 -29.403 37.492  1   63.93  ? 209 SER D O   1 
ATOM   319  C CB  . SER A 1 39  ? -35.329 -32.101 35.825  1   62.38  ? 209 SER D CB  1 
ATOM   320  O OG  . SER A 1 39  ? -35.629 -32.577 37.13   1   61.02  ? 209 SER D OG  1 
ATOM   321  N N   . MET A 1 40  ? -34.383 -29.209 36.398  1   59.4   ? 210 MET D N   1 
ATOM   322  C CA  . MET A 1 40  ? -33.831 -28.251 37.344  1   57.14  ? 210 MET D CA  1 
ATOM   323  C C   . MET A 1 40  ? -34.612 -26.959 37.256  1   53.16  ? 210 MET D C   1 
ATOM   324  O O   . MET A 1 40  ? -34.82  -26.309 38.278  1   52.85  ? 210 MET D O   1 
ATOM   325  C CB  . MET A 1 40  ? -32.348 -27.961 37.098  1   54.44  ? 210 MET D CB  1 
ATOM   326  C CG  . MET A 1 40  ? -31.501 -29.169 37.35   1   55.3   ? 210 MET D CG  1 
ATOM   327  S SD  . MET A 1 40  ? -29.824 -28.804 36.825  1   54.13  ? 210 MET D SD  1 
ATOM   328  C CE  . MET A 1 40  ? -29.14  -30.465 36.662  1   51.75  ? 210 MET D CE  1 
ATOM   329  N N   . ARG A 1 41  ? -35.042 -26.643 36.033  1   52.61  ? 211 ARG D N   1 
ATOM   330  C CA  . ARG A 1 41  ? -35.739 -25.399 35.76   1   51.78  ? 211 ARG D CA  1 
ATOM   331  C C   . ARG A 1 41  ? -37.098 -25.44  36.448  1   51.46  ? 211 ARG D C   1 
ATOM   332  O O   . ARG A 1 41  ? -37.488 -24.448 37.059  1   51.92  ? 211 ARG D O   1 
ATOM   333  C CB  . ARG A 1 41  ? -35.878 -25.173 34.249  1   51.06  ? 211 ARG D CB  1 
ATOM   334  C CG  . ARG A 1 41  ? -36.722 -23.953 33.884  1   47     ? 211 ARG D CG  1 
ATOM   335  C CD  . ARG A 1 41  ? -36.912 -23.841 32.371  1   47.63  ? 211 ARG D CD  1 
ATOM   336  N NE  . ARG A 1 41  ? -37.864 -22.801 31.979  1   48.15  ? 211 ARG D NE  1 
ATOM   337  C CZ  . ARG A 1 41  ? -39.14  -22.767 32.351  1   46.97  ? 211 ARG D CZ  1 
ATOM   338  N NH1 . ARG A 1 41  ? -39.652 -23.785 33.017  1   44.89  ? 211 ARG D NH1 1 
ATOM   339  N NH2 . ARG A 1 41  ? -39.887 -21.706 32.068  1   45.05  ? 211 ARG D NH2 1 
ATOM   340  N N   . ALA A 1 42  ? -37.79  -26.584 36.319  1   51.79  ? 212 ALA D N   1 
ATOM   341  C CA  . ALA A 1 42  ? -39.053 -26.833 36.999  1   53.35  ? 212 ALA D CA  1 
ATOM   342  C C   . ALA A 1 42  ? -38.906 -26.601 38.508  1   54.32  ? 212 ALA D C   1 
ATOM   343  O O   . ALA A 1 42  ? -39.73  -25.905 39.1    1   56.41  ? 212 ALA D O   1 
ATOM   344  C CB  . ALA A 1 42  ? -39.57  -28.222 36.692  1   51.37  ? 212 ALA D CB  1 
ATOM   345  N N   . ILE A 1 43  ? -37.849 -27.153 39.121  1   53.3   ? 213 ILE D N   1 
ATOM   346  C CA  . ILE A 1 43  ? -37.594 -26.921 40.536  1   53.15  ? 213 ILE D CA  1 
ATOM   347  C C   . ILE A 1 43  ? -37.442 -25.426 40.829  1   53.52  ? 213 ILE D C   1 
ATOM   348  O O   . ILE A 1 43  ? -37.919 -24.931 41.852  1   54.63  ? 213 ILE D O   1 
ATOM   349  C CB  . ILE A 1 43  ? -36.365 -27.717 40.992  1   53.03  ? 213 ILE D CB  1 
ATOM   350  C CG1 . ILE A 1 43  ? -36.682 -29.213 40.986  1   53.86  ? 213 ILE D CG1 1 
ATOM   351  C CG2 . ILE A 1 43  ? -35.866 -27.231 42.355  1   49.95  ? 213 ILE D CG2 1 
ATOM   352  C CD1 . ILE A 1 43  ? -35.461 -30.085 41.16   1   54.65  ? 213 ILE D CD1 1 
ATOM   353  N N   . LEU A 1 44  ? -36.788 -24.702 39.918  1   51.04  ? 214 LEU D N   1 
ATOM   354  C CA  . LEU A 1 44  ? -36.552 -23.286 40.115  1   49.83  ? 214 LEU D CA  1 
ATOM   355  C C   . LEU A 1 44  ? -37.874 -22.516 40.087  1   49.95  ? 214 LEU D C   1 
ATOM   356  O O   . LEU A 1 44  ? -38.139 -21.694 40.969  1   49.7   ? 214 LEU D O   1 
ATOM   357  C CB  . LEU A 1 44  ? -35.566 -22.779 39.061  1   48.54  ? 214 LEU D CB  1 
ATOM   358  C CG  . LEU A 1 44  ? -35.252 -21.278 39.127  1   45.41  ? 214 LEU D CG  1 
ATOM   359  C CD1 . LEU A 1 44  ? -34.52  -20.954 40.41   1   44.71  ? 214 LEU D CD1 1 
ATOM   360  C CD2 . LEU A 1 44  ? -34.458 -20.801 37.913  1   42.91  ? 214 LEU D CD2 1 
ATOM   361  N N   . VAL A 1 45  ? -38.675 -22.752 39.041  1   49.49  ? 215 VAL D N   1 
ATOM   362  C CA  . VAL A 1 45  ? -39.903 -21.993 38.872  1   50.33  ? 215 VAL D CA  1 
ATOM   363  C C   . VAL A 1 45  ? -40.819 -22.296 40.056  1   50.84  ? 215 VAL D C   1 
ATOM   364  O O   . VAL A 1 45  ? -41.505 -21.403 40.55   1   49.32  ? 215 VAL D O   1 
ATOM   365  C CB  . VAL A 1 45  ? -40.597 -22.265 37.523  1   49.49  ? 215 VAL D CB  1 
ATOM   366  C CG1 . VAL A 1 45  ? -41.897 -21.48  37.391  1   49.72  ? 215 VAL D CG1 1 
ATOM   367  C CG2 . VAL A 1 45  ? -39.684 -21.945 36.355  1   46.47  ? 215 VAL D CG2 1 
ATOM   368  N N   . ASP A 1 46  ? -40.813 -23.561 40.5    1   52.69  ? 216 ASP D N   1 
ATOM   369  C CA  . ASP A 1 46  ? -41.712 -24.003 41.558  1   55.91  ? 216 ASP D CA  1 
ATOM   370  C C   . ASP A 1 46  ? -41.338 -23.269 42.835  1   56.09  ? 216 ASP D C   1 
ATOM   371  O O   . ASP A 1 46  ? -42.203 -22.854 43.604  1   57.21  ? 216 ASP D O   1 
ATOM   372  C CB  . ASP A 1 46  ? -41.703 -25.509 41.744  1   55.37  ? 216 ASP D CB  1 
ATOM   373  C CG  . ASP A 1 46  ? -42.687 -26.014 42.779  1   57.51  ? 216 ASP D CG  1 
ATOM   374  O OD1 . ASP A 1 46  ? -42.348 -25.95  43.964  1   59.56  ? 216 ASP D OD1 1 
ATOM   375  O OD2 . ASP A 1 46  ? -43.787 -26.432 42.387  1   60.02  ? 216 ASP D OD2 1 
ATOM   376  N N   . TRP A 1 47  ? -40.029 -23.083 43.015  1   54.44  ? 217 TRP D N   1 
ATOM   377  C CA  . TRP A 1 47  ? -39.535 -22.335 44.151  1   53.18  ? 217 TRP D CA  1 
ATOM   378  C C   . TRP A 1 47  ? -39.97  -20.861 44.05   1   53.1   ? 217 TRP D C   1 
ATOM   379  O O   . TRP A 1 47  ? -40.435 -20.287 45.029  1   53.68  ? 217 TRP D O   1 
ATOM   380  C CB  . TRP A 1 47  ? -38.024 -22.544 44.275  1   49.73  ? 217 TRP D CB  1 
ATOM   381  C CG  . TRP A 1 47  ? -37.444 -21.657 45.334  1   51.67  ? 217 TRP D CG  1 
ATOM   382  C CD1 . TRP A 1 47  ? -37.579 -21.8   46.686  1   52.03  ? 217 TRP D CD1 1 
ATOM   383  C CD2 . TRP A 1 47  ? -36.652 -20.471 45.119  1   47.83  ? 217 TRP D CD2 1 
ATOM   384  N NE1 . TRP A 1 47  ? -36.903 -20.796 47.329  1   51.06  ? 217 TRP D NE1 1 
ATOM   385  C CE2 . TRP A 1 47  ? -36.318 -19.974 46.397  1   48.62  ? 217 TRP D CE2 1 
ATOM   386  C CE3 . TRP A 1 47  ? -36.168 -19.815 43.985  1   46.85  ? 217 TRP D CE3 1 
ATOM   387  C CZ2 . TRP A 1 47  ? -35.534 -18.84  46.574  1   46.16  ? 217 TRP D CZ2 1 
ATOM   388  C CZ3 . TRP A 1 47  ? -35.389 -18.689 44.16   1   46.01  ? 217 TRP D CZ3 1 
ATOM   389  C CH2 . TRP A 1 47  ? -35.088 -18.205 45.439  1   45.83  ? 217 TRP D CH2 1 
ATOM   390  N N   . LEU A 1 48  ? -39.897 -20.27  42.849  1   50.17  ? 218 LEU D N   1 
ATOM   391  C CA  . LEU A 1 48  ? -40.336 -18.898 42.647  1   49.55  ? 218 LEU D CA  1 
ATOM   392  C C   . LEU A 1 48  ? -41.827 -18.721 42.967  1   52.73  ? 218 LEU D C   1 
ATOM   393  O O   . LEU A 1 48  ? -42.256 -17.653 43.401  1   55.36  ? 218 LEU D O   1 
ATOM   394  C CB  . LEU A 1 48  ? -39.971 -18.449 41.232  1   46.72  ? 218 LEU D CB  1 
ATOM   395  C CG  . LEU A 1 48  ? -38.47  -18.258 40.981  1   48.67  ? 218 LEU D CG  1 
ATOM   396  C CD1 . LEU A 1 48  ? -38.193 -17.683 39.596  1   47.13  ? 218 LEU D CD1 1 
ATOM   397  C CD2 . LEU A 1 48  ? -37.81  -17.385 42.039  1   43.02  ? 218 LEU D CD2 1 
ATOM   398  N N   . VAL A 1 49  ? -42.634 -19.762 42.744  1   53.59  ? 219 VAL D N   1 
ATOM   399  C CA  . VAL A 1 49  ? -44.045 -19.722 43.088  1   56.37  ? 219 VAL D CA  1 
ATOM   400  C C   . VAL A 1 49  ? -44.194 -19.586 44.608  1   55.98  ? 219 VAL D C   1 
ATOM   401  O O   . VAL A 1 49  ? -44.887 -18.694 45.07   1   57.47  ? 219 VAL D O   1 
ATOM   402  C CB  . VAL A 1 49  ? -44.798 -20.941 42.501  1   59.11  ? 219 VAL D CB  1 
ATOM   403  C CG1 . VAL A 1 49  ? -46.194 -21.103 43.089  1   57.56  ? 219 VAL D CG1 1 
ATOM   404  C CG2 . VAL A 1 49  ? -44.863 -20.878 40.976  1   57.68  ? 219 VAL D CG2 1 
ATOM   405  N N   . GLU A 1 50  ? -43.523 -20.446 45.383  1   56.03  ? 220 GLU D N   1 
ATOM   406  C CA  . GLU A 1 50  ? -43.473 -20.317 46.841  1   58.86  ? 220 GLU D CA  1 
ATOM   407  C C   . GLU A 1 50  ? -43.048 -18.912 47.267  1   54.51  ? 220 GLU D C   1 
ATOM   408  O O   . GLU A 1 50  ? -43.756 -18.252 48.003  1   52.88  ? 220 GLU D O   1 
ATOM   409  C CB  . GLU A 1 50  ? -42.469 -21.286 47.467  1   62.15  ? 220 GLU D CB  1 
ATOM   410  C CG  . GLU A 1 50  ? -43.123 -22.488 48.137  1   69     ? 220 GLU D CG  1 
ATOM   411  C CD  . GLU A 1 50  ? -42.221 -23.711 48.219  1   76.77  ? 220 GLU D CD  1 
ATOM   412  O OE1 . GLU A 1 50  ? -42.765 -24.76  48.661  1   82.37  ? 220 GLU D OE1 1 
ATOM   413  O OE2 . GLU A 1 50  ? -41.016 -23.629 47.836  1   74.51  ? 220 GLU D OE2 1 
ATOM   414  N N   . VAL A 1 51  ? -41.883 -18.47  46.797  1   51.81  ? 221 VAL D N   1 
ATOM   415  C CA  . VAL A 1 51  ? -41.387 -17.137 47.091  1   53.12  ? 221 VAL D CA  1 
ATOM   416  C C   . VAL A 1 51  ? -42.491 -16.117 46.827  1   54.03  ? 221 VAL D C   1 
ATOM   417  O O   . VAL A 1 51  ? -42.735 -15.251 47.669  1   54.75  ? 221 VAL D O   1 
ATOM   418  C CB  . VAL A 1 51  ? -40.086 -16.825 46.315  1   49.42  ? 221 VAL D CB  1 
ATOM   419  C CG1 . VAL A 1 51  ? -39.726 -15.348 46.342  1   45.78  ? 221 VAL D CG1 1 
ATOM   420  C CG2 . VAL A 1 51  ? -38.936 -17.644 46.879  1   48.82  ? 221 VAL D CG2 1 
ATOM   421  N N   . GLY A 1 52  ? -43.173 -16.254 45.679  1   51.07  ? 222 GLY D N   1 
ATOM   422  C CA  . GLY A 1 52  ? -44.26  -15.347 45.338  1   52.33  ? 222 GLY D CA  1 
ATOM   423  C C   . GLY A 1 52  ? -45.415 -15.348 46.354  1   55.9   ? 222 GLY D C   1 
ATOM   424  O O   . GLY A 1 52  ? -46.088 -14.323 46.495  1   57.39  ? 222 GLY D O   1 
ATOM   425  N N   . GLU A 1 53  ? -45.616 -16.45  47.069  1   58.43  ? 223 GLU D N   1 
ATOM   426  C CA  . GLU A 1 53  ? -46.726 -16.544 48.053  1   62.99  ? 223 GLU D CA  1 
ATOM   427  C C   . GLU A 1 53  ? -46.244 -16.018 49.409  1   62.81  ? 223 GLU D C   1 
ATOM   428  O O   . GLU A 1 53  ? -47.015 -15.297 50.053  1   64.92  ? 223 GLU D O   1 
ATOM   429  C CB  . GLU A 1 53  ? -47.231 -17.985 48.073  1   65.48  ? 223 GLU D CB  1 
ATOM   430  C CG  . GLU A 1 53  ? -48.014 -18.354 46.818  1   76.85  ? 223 GLU D CG  1 
ATOM   431  C CD  . GLU A 1 53  ? -49.05  -17.316 46.426  1   83.74  ? 223 GLU D CD  1 
ATOM   432  O OE1 . GLU A 1 53  ? -50.164 -17.366 46.982  1   81.52  ? 223 GLU D OE1 1 
ATOM   433  O OE2 . GLU A 1 53  ? -48.751 -16.465 45.564  1   80.65  ? 223 GLU D OE2 1 
ATOM   434  N N   . GLU A 1 54  ? -45.021 -16.353 49.808  1   63.54  ? 224 GLU D N   1 
ATOM   435  C CA  . GLU A 1 54  ? -44.422 -15.865 51.05   1   64.51  ? 224 GLU D CA  1 
ATOM   436  C C   . GLU A 1 54  ? -44.347 -14.332 51.076  1   59.95  ? 224 GLU D C   1 
ATOM   437  O O   . GLU A 1 54  ? -44.476 -13.716 52.13   1   61.01  ? 224 GLU D O   1 
ATOM   438  C CB  . GLU A 1 54  ? -43.084 -16.59  51.233  1   68.63  ? 224 GLU D CB  1 
ATOM   439  C CG  . GLU A 1 54  ? -42.11  -15.998 52.248  1   74.16  ? 224 GLU D CG  1 
ATOM   440  C CD  . GLU A 1 54  ? -42.377 -16.203 53.731  1   93.42  ? 224 GLU D CD  1 
ATOM   441  O OE1 . GLU A 1 54  ? -43.445 -16.779 54.067  1   101.91 ? 224 GLU D OE1 1 
ATOM   442  O OE2 . GLU A 1 54  ? -41.524 -15.783 54.56   1   92.29  ? 224 GLU D OE2 1 
ATOM   443  N N   . TYR A 1 55  ? -44.165 -13.706 49.915  1   55.42  ? 225 TYR D N   1 
ATOM   444  C CA  . TYR A 1 55  ? -44.002 -12.262 49.854  1   55.98  ? 225 TYR D CA  1 
ATOM   445  C C   . TYR A 1 55  ? -45.251 -11.571 49.3    1   58.51  ? 225 TYR D C   1 
ATOM   446  O O   . TYR A 1 55  ? -45.235 -10.365 49.053  1   58.12  ? 225 TYR D O   1 
ATOM   447  C CB  . TYR A 1 55  ? -42.702 -11.944 49.1    1   51.86  ? 225 TYR D CB  1 
ATOM   448  C CG  . TYR A 1 55  ? -41.488 -12.25  49.958  1   52.95  ? 225 TYR D CG  1 
ATOM   449  C CD1 . TYR A 1 55  ? -41.113 -11.406 50.997  1   55.2   ? 225 TYR D CD1 1 
ATOM   450  C CD2 . TYR A 1 55  ? -40.783 -13.434 49.805  1   54.99  ? 225 TYR D CD2 1 
ATOM   451  C CE1 . TYR A 1 55  ? -40.053 -11.716 51.837  1   58.48  ? 225 TYR D CE1 1 
ATOM   452  C CE2 . TYR A 1 55  ? -39.715 -13.753 50.638  1   57.17  ? 225 TYR D CE2 1 
ATOM   453  C CZ  . TYR A 1 55  ? -39.335 -12.889 51.655  1   58.77  ? 225 TYR D CZ  1 
ATOM   454  O OH  . TYR A 1 55  ? -38.254 -13.163 52.461  1   56.4   ? 225 TYR D OH  1 
ATOM   455  N N   . LYS A 1 56  ? -46.324 -12.349 49.096  1   63.08  ? 226 LYS D N   1 
ATOM   456  C CA  . LYS A 1 56  ? -47.586 -11.883 48.527  1   60.99  ? 226 LYS D CA  1 
ATOM   457  C C   . LYS A 1 56  ? -47.324 -11.069 47.263  1   55.71  ? 226 LYS D C   1 
ATOM   458  O O   . LYS A 1 56  ? -47.8   -9.937  47.164  1   56.81  ? 226 LYS D O   1 
ATOM   459  C CB  . LYS A 1 56  ? -48.42  -11.051 49.511  1   64.46  ? 226 LYS D CB  1 
ATOM   460  C CG  . LYS A 1 56  ? -48.614 -11.668 50.889  1   74.09  ? 226 LYS D CG  1 
ATOM   461  C CD  . LYS A 1 56  ? -49.383 -12.983 50.849  1   84.23  ? 226 LYS D CD  1 
ATOM   462  C CE  . LYS A 1 56  ? -49.507 -13.627 52.197  1   90.07  ? 226 LYS D CE  1 
ATOM   463  N NZ  . LYS A 1 56  ? -50.079 -14.963 52.007  1   95.43  ? 226 LYS D NZ  1 
ATOM   464  N N   . LEU A 1 57  ? -46.556 -11.634 46.325  1   49.5   ? 227 LEU D N   1 
ATOM   465  C CA  . LEU A 1 57  ? -46.208 -10.894 45.119  1   49.93  ? 227 LEU D CA  1 
ATOM   466  C C   . LEU A 1 57  ? -47.321 -11.059 44.097  1   51.03  ? 227 LEU D C   1 
ATOM   467  O O   . LEU A 1 57  ? -47.947 -12.118 44.066  1   52.11  ? 227 LEU D O   1 
ATOM   468  C CB  . LEU A 1 57  ? -44.888 -11.407 44.535  1   46.75  ? 227 LEU D CB  1 
ATOM   469  C CG  . LEU A 1 57  ? -43.659 -11.239 45.443  1   45.86  ? 227 LEU D CG  1 
ATOM   470  C CD1 . LEU A 1 57  ? -42.429 -11.807 44.747  1   43.11  ? 227 LEU D CD1 1 
ATOM   471  C CD2 . LEU A 1 57  ? -43.446 -9.8    45.88   1   43.91  ? 227 LEU D CD2 1 
ATOM   472  N N   . GLN A 1 58  ? -47.451 -10.081 43.185  1   50.32  ? 228 GLN D N   1 
ATOM   473  C CA  . GLN A 1 58  ? -48.345 -10.244 42.045  1   50.64  ? 228 GLN D CA  1 
ATOM   474  C C   . GLN A 1 58  ? -47.963 -11.483 41.231  1   52.61  ? 228 GLN D C   1 
ATOM   475  O O   . GLN A 1 58  ? -46.786 -11.818 41.074  1   51.75  ? 228 GLN D O   1 
ATOM   476  C CB  . GLN A 1 58  ? -48.288 -9.027  41.132  1   47.64  ? 228 GLN D CB  1 
ATOM   477  C CG  . GLN A 1 58  ? -48.753 -7.755  41.817  1   51.75  ? 228 GLN D CG  1 
ATOM   478  C CD  . GLN A 1 58  ? -50.235 -7.811  42.124  1   59.25  ? 228 GLN D CD  1 
ATOM   479  O OE1 . GLN A 1 58  ? -51.074 -7.881  41.22   1   68.63  ? 228 GLN D OE1 1 
ATOM   480  N NE2 . GLN A 1 58  ? -50.576 -7.837  43.403  1   54.59  ? 228 GLN D NE2 1 
ATOM   481  N N   . ASN A 1 59  ? -48.978 -12.144 40.675  1   52.38  ? 229 ASN D N   1 
ATOM   482  C CA  . ASN A 1 59  ? -48.742 -13.254 39.776  1   51.05  ? 229 ASN D CA  1 
ATOM   483  C C   . ASN A 1 59  ? -47.966 -12.783 38.562  1   47.13  ? 229 ASN D C   1 
ATOM   484  O O   . ASN A 1 59  ? -47.217 -13.569 37.985  1   46.14  ? 229 ASN D O   1 
ATOM   485  C CB  . ASN A 1 59  ? -50.052 -13.886 39.322  1   55.48  ? 229 ASN D CB  1 
ATOM   486  C CG  . ASN A 1 59  ? -50.709 -14.677 40.432  1   57.44  ? 229 ASN D CG  1 
ATOM   487  O OD1 . ASN A 1 59  ? -50.064 -15.104 41.404  1   55.68  ? 229 ASN D OD1 1 
ATOM   488  N ND2 . ASN A 1 59  ? -51.996 -14.912 40.277  1   57.72  ? 229 ASN D ND2 1 
ATOM   489  N N   . GLU A 1 60  ? -48.21  -11.528 38.165  1   46.17  ? 230 GLU D N   1 
ATOM   490  C CA  . GLU A 1 60  ? -47.569 -10.943 36.999  1   46.1   ? 230 GLU D CA  1 
ATOM   491  C C   . GLU A 1 60  ? -46.056 -10.901 37.223  1   45.95  ? 230 GLU D C   1 
ATOM   492  O O   . GLU A 1 60  ? -45.289 -11.082 36.285  1   46.54  ? 230 GLU D O   1 
ATOM   493  C CB  . GLU A 1 60  ? -48.194 -9.583  36.7    1   43.26  ? 230 GLU D CB  1 
ATOM   494  C CG  . GLU A 1 60  ? -47.461 -8.781  35.629  1   44.16  ? 230 GLU D CG  1 
ATOM   495  C CD  . GLU A 1 60  ? -47.492 -9.229  34.182  1   44.43  ? 230 GLU D CD  1 
ATOM   496  O OE1 . GLU A 1 60  ? -48.219 -10.194 33.891  1   45.46  ? 230 GLU D OE1 1 
ATOM   497  O OE2 . GLU A 1 60  ? -46.807 -8.586  33.347  1   44.31  ? 230 GLU D OE2 1 
ATOM   498  N N   . THR A 1 61  ? -45.638 -10.681 38.477  1   45.86  ? 231 THR D N   1 
ATOM   499  C CA  . THR A 1 61  ? -44.229 -10.635 38.837  1   44.4   ? 231 THR D CA  1 
ATOM   500  C C   . THR A 1 61  ? -43.596 -11.995 38.544  1   48.74  ? 231 THR D C   1 
ATOM   501  O O   . THR A 1 61  ? -42.541 -12.043 37.905  1   50.08  ? 231 THR D O   1 
ATOM   502  C CB  . THR A 1 61  ? -44.053 -10.216 40.292  1   44.92  ? 231 THR D CB  1 
ATOM   503  O OG1 . THR A 1 61  ? -44.732 -8.973  40.427  1   46.5   ? 231 THR D OG1 1 
ATOM   504  C CG2 . THR A 1 61  ? -42.607 -9.942  40.649  1   45.17  ? 231 THR D CG2 1 
ATOM   505  N N   . LEU A 1 62  ? -44.252 -13.079 38.984  1   47.8   ? 232 LEU D N   1 
ATOM   506  C CA  . LEU A 1 62  ? -43.793 -14.442 38.757  1   47.69  ? 232 LEU D CA  1 
ATOM   507  C C   . LEU A 1 62  ? -43.618 -14.718 37.271  1   48.65  ? 232 LEU D C   1 
ATOM   508  O O   . LEU A 1 62  ? -42.624 -15.321 36.873  1   52.71  ? 232 LEU D O   1 
ATOM   509  C CB  . LEU A 1 62  ? -44.733 -15.456 39.408  1   49.11  ? 232 LEU D CB  1 
ATOM   510  C CG  . LEU A 1 62  ? -44.53  -16.933 39.055  1   51.39  ? 232 LEU D CG  1 
ATOM   511  C CD1 . LEU A 1 62  ? -43.281 -17.506 39.674  1   53.45  ? 232 LEU D CD1 1 
ATOM   512  C CD2 . LEU A 1 62  ? -45.726 -17.769 39.49   1   53.29  ? 232 LEU D CD2 1 
ATOM   513  N N   . HIS A 1 63  ? -44.583 -14.304 36.446  1   49.3   ? 233 HIS D N   1 
ATOM   514  C CA  . HIS A 1 63  ? -44.501 -14.574 35.012  1   49.83  ? 233 HIS D CA  1 
ATOM   515  C C   . HIS A 1 63  ? -43.32  -13.817 34.387  1   50.51  ? 233 HIS D C   1 
ATOM   516  O O   . HIS A 1 63  ? -42.599 -14.359 33.54   1   52.59  ? 233 HIS D O   1 
ATOM   517  C CB  . HIS A 1 63  ? -45.774 -14.13  34.282  1   48.58  ? 233 HIS D CB  1 
ATOM   518  C CG  . HIS A 1 63  ? -46.898 -15.107 34.309  1   50.03  ? 233 HIS D CG  1 
ATOM   519  N ND1 . HIS A 1 63  ? -47.686 -15.318 35.428  1   47.67  ? 233 HIS D ND1 1 
ATOM   520  C CD2 . HIS A 1 63  ? -47.352 -15.933 33.347  1   47.72  ? 233 HIS D CD2 1 
ATOM   521  C CE1 . HIS A 1 63  ? -48.577 -16.249 35.147  1   48.17  ? 233 HIS D CE1 1 
ATOM   522  N NE2 . HIS A 1 63  ? -48.393 -16.634 33.906  1   48.29  ? 233 HIS D NE2 1 
ATOM   523  N N   . LEU A 1 64  ? -43.167 -12.544 34.783  1   44.99  ? 234 LEU D N   1 
ATOM   524  C CA  . LEU A 1 64  ? -42.064 -11.725 34.333  1   43.3   ? 234 LEU D CA  1 
ATOM   525  C C   . LEU A 1 64  ? -40.746 -12.405 34.704  1   46.57  ? 234 LEU D C   1 
ATOM   526  O O   . LEU A 1 64  ? -39.866 -12.579 33.84   1   47.02  ? 234 LEU D O   1 
ATOM   527  C CB  . LEU A 1 64  ? -42.178 -10.332 34.925  1   40.45  ? 234 LEU D CB  1 
ATOM   528  C CG  . LEU A 1 64  ? -43.219 -9.426  34.27   1   40.43  ? 234 LEU D CG  1 
ATOM   529  C CD1 . LEU A 1 64  ? -43.282 -8.113  35.038  1   40.62  ? 234 LEU D CD1 1 
ATOM   530  C CD2 . LEU A 1 64  ? -42.915 -9.184  32.809  1   35.95  ? 234 LEU D CD2 1 
ATOM   531  N N   . ALA A 1 65  ? -40.635 -12.866 35.962  1   45.77  ? 235 ALA D N   1 
ATOM   532  C CA  . ALA A 1 65  ? -39.379 -13.464 36.403  1   44.53  ? 235 ALA D CA  1 
ATOM   533  C C   . ALA A 1 65  ? -38.983 -14.619 35.484  1   43.32  ? 235 ALA D C   1 
ATOM   534  O O   . ALA A 1 65  ? -37.8   -14.789 35.201  1   43.2   ? 235 ALA D O   1 
ATOM   535  C CB  . ALA A 1 65  ? -39.457 -13.9   37.845  1   43.39  ? 235 ALA D CB  1 
ATOM   536  N N   . VAL A 1 66  ? -39.974 -15.402 35.032  1   42.61  ? 236 VAL D N   1 
ATOM   537  C CA  . VAL A 1 66  ? -39.707 -16.626 34.297  1   42.81  ? 236 VAL D CA  1 
ATOM   538  C C   . VAL A 1 66  ? -39.28  -16.245 32.879  1   46.28  ? 236 VAL D C   1 
ATOM   539  O O   . VAL A 1 66  ? -38.38  -16.863 32.305  1   45.47  ? 236 VAL D O   1 
ATOM   540  C CB  . VAL A 1 66  ? -40.925 -17.563 34.318  1   42.66  ? 236 VAL D CB  1 
ATOM   541  C CG1 . VAL A 1 66  ? -40.716 -18.772 33.423  1   40.04  ? 236 VAL D CG1 1 
ATOM   542  C CG2 . VAL A 1 66  ? -41.303 -17.981 35.748  1   42.09  ? 236 VAL D CG2 1 
ATOM   543  N N   . ASN A 1 67  ? -39.913 -15.192 32.335  1   43.02  ? 237 ASN D N   1 
ATOM   544  C CA  . ASN A 1 67  ? -39.478 -14.707 31.045  1   41.77  ? 237 ASN D CA  1 
ATOM   545  C C   . ASN A 1 67  ? -37.997 -14.288 31.119  1   42.69  ? 237 ASN D C   1 
ATOM   546  O O   . ASN A 1 67  ? -37.22  -14.564 30.206  1   41.98  ? 237 ASN D O   1 
ATOM   547  C CB  . ASN A 1 67  ? -40.399 -13.607 30.556  1   39.29  ? 237 ASN D CB  1 
ATOM   548  C CG  . ASN A 1 67  ? -39.919 -13.053 29.238  1   42.26  ? 237 ASN D CG  1 
ATOM   549  O OD1 . ASN A 1 67  ? -39.211 -12.029 29.226  1   43.03  ? 237 ASN D OD1 1 
ATOM   550  N ND2 . ASN A 1 67  ? -40.25  -13.734 28.137  1   41.81  ? 237 ASN D ND2 1 
ATOM   551  N N   . TYR A 1 68  ? -37.611 -13.579 32.19   1   43.1   ? 238 TYR D N   1 
ATOM   552  C CA  . TYR A 1 68  ? -36.253 -13.059 32.373  1   42.57  ? 238 TYR D CA  1 
ATOM   553  C C   . TYR A 1 68  ? -35.256 -14.225 32.359  1   43.97  ? 238 TYR D C   1 
ATOM   554  O O   . TYR A 1 68  ? -34.275 -14.211 31.597  1   44.22  ? 238 TYR D O   1 
ATOM   555  C CB  . TYR A 1 68  ? -36.124 -12.192 33.638  1   41.03  ? 238 TYR D CB  1 
ATOM   556  C CG  . TYR A 1 68  ? -37.01  -10.95  33.657  1   40.75  ? 238 TYR D CG  1 
ATOM   557  C CD1 . TYR A 1 68  ? -37.679 -10.534 32.512  1   41.39  ? 238 TYR D CD1 1 
ATOM   558  C CD2 . TYR A 1 68  ? -37.203 -10.206 34.814  1   40.07  ? 238 TYR D CD2 1 
ATOM   559  C CE1 . TYR A 1 68  ? -38.517 -9.426  32.512  1   42.21  ? 238 TYR D CE1 1 
ATOM   560  C CE2 . TYR A 1 68  ? -38.056 -9.109  34.832  1   41.71  ? 238 TYR D CE2 1 
ATOM   561  C CZ  . TYR A 1 68  ? -38.726 -8.722  33.679  1   43.16  ? 238 TYR D CZ  1 
ATOM   562  O OH  . TYR A 1 68  ? -39.539 -7.628  33.608  1   44.56  ? 238 TYR D OH  1 
ATOM   563  N N   . ILE A 1 69  ? -35.59  -15.27  33.138  1   43.63  ? 239 ILE D N   1 
ATOM   564  C CA  . ILE A 1 69  ? -34.777 -16.469 33.282  1   42.89  ? 239 ILE D CA  1 
ATOM   565  C C   . ILE A 1 69  ? -34.581 -17.151 31.932  1   45.72  ? 239 ILE D C   1 
ATOM   566  O O   . ILE A 1 69  ? -33.46  -17.478 31.571  1   47.39  ? 239 ILE D O   1 
ATOM   567  C CB  . ILE A 1 69  ? -35.391 -17.407 34.33   1   41.28  ? 239 ILE D CB  1 
ATOM   568  C CG1 . ILE A 1 69  ? -35.393 -16.712 35.716  1   40     ? 239 ILE D CG1 1 
ATOM   569  C CG2 . ILE A 1 69  ? -34.659 -18.744 34.363  1   39.33  ? 239 ILE D CG2 1 
ATOM   570  C CD1 . ILE A 1 69  ? -36.178 -17.455 36.795  1   37.94  ? 239 ILE D CD1 1 
ATOM   571  N N   . ASP A 1 70  ? -35.669 -17.391 31.191  1   46.44  ? 240 ASP D N   1 
ATOM   572  C CA  . ASP A 1 70  ? -35.55  -18.198 29.99   1   46.37  ? 240 ASP D CA  1 
ATOM   573  C C   . ASP A 1 70  ? -34.722 -17.447 28.96   1   44.32  ? 240 ASP D C   1 
ATOM   574  O O   . ASP A 1 70  ? -34.011 -18.07  28.184  1   43.88  ? 240 ASP D O   1 
ATOM   575  C CB  . ASP A 1 70  ? -36.891 -18.662 29.433  1   47.5   ? 240 ASP D CB  1 
ATOM   576  C CG  . ASP A 1 70  ? -37.649 -19.642 30.315  1   48.8   ? 240 ASP D CG  1 
ATOM   577  O OD1 . ASP A 1 70  ? -36.972 -20.49  30.947  1   49.26  ? 240 ASP D OD1 1 
ATOM   578  O OD2 . ASP A 1 70  ? -38.902 -19.554 30.361  1   46.93  ? 240 ASP D OD2 1 
ATOM   579  N N   . ARG A 1 71  ? -34.845 -16.118 28.94   1   43.07  ? 241 ARG D N   1 
ATOM   580  C CA  . ARG A 1 71  ? -34.098 -15.305 27.945  1   42.19  ? 241 ARG D CA  1 
ATOM   581  C C   . ARG A 1 71  ? -32.618 -15.271 28.351  1   43.89  ? 241 ARG D C   1 
ATOM   582  O O   . ARG A 1 71  ? -31.754 -15.354 27.453  1   47.15  ? 241 ARG D O   1 
ATOM   583  C CB  . ARG A 1 71  ? -34.715 -13.907 27.85   1   40.46  ? 241 ARG D CB  1 
ATOM   584  C CG  . ARG A 1 71  ? -36.082 -13.887 27.182  1   45     ? 241 ARG D CG  1 
ATOM   585  C CD  . ARG A 1 71  ? -36.625 -12.472 27.084  1   45.68  ? 241 ARG D CD  1 
ATOM   586  N NE  . ARG A 1 71  ? -36.535 -11.737 28.35   1   46.27  ? 241 ARG D NE  1 
ATOM   587  C CZ  . ARG A 1 71  ? -36.585 -10.414 28.444  1   46.44  ? 241 ARG D CZ  1 
ATOM   588  N NH1 . ARG A 1 71  ? -35.771 -9.669  27.718  1   43.61  ? 241 ARG D NH1 1 
ATOM   589  N NH2 . ARG A 1 71  ? -37.455 -9.84   29.254  1   43.53  ? 241 ARG D NH2 1 
ATOM   590  N N   . PHE A 1 72  ? -32.34  -15.149 29.651  1   42.8   ? 242 PHE D N   1 
ATOM   591  C CA  . PHE A 1 72  ? -30.969 -15.164 30.129  1   42.98  ? 242 PHE D CA  1 
ATOM   592  C C   . PHE A 1 72  ? -30.29  -16.482 29.759  1   44.5   ? 242 PHE D C   1 
ATOM   593  O O   . PHE A 1 72  ? -29.185 -16.497 29.212  1   47.02  ? 242 PHE D O   1 
ATOM   594  C CB  . PHE A 1 72  ? -30.928 -14.889 31.627  1   41.24  ? 242 PHE D CB  1 
ATOM   595  C CG  . PHE A 1 72  ? -29.514 -14.706 32.153  1   41.65  ? 242 PHE D CG  1 
ATOM   596  C CD1 . PHE A 1 72  ? -28.895 -13.466 32.105  1   41.64  ? 242 PHE D CD1 1 
ATOM   597  C CD2 . PHE A 1 72  ? -28.813 -15.787 32.685  1   44.02  ? 242 PHE D CD2 1 
ATOM   598  C CE1 . PHE A 1 72  ? -27.619 -13.311 32.635  1   42.51  ? 242 PHE D CE1 1 
ATOM   599  C CE2 . PHE A 1 72  ? -27.54  -15.64  33.203  1   42.85  ? 242 PHE D CE2 1 
ATOM   600  C CZ  . PHE A 1 72  ? -26.952 -14.397 33.178  1   42.52  ? 242 PHE D CZ  1 
ATOM   601  N N   . LEU A 1 73  ? -30.956 -17.591 30.074  1   43.81  ? 243 LEU D N   1 
ATOM   602  C CA  . LEU A 1 73  ? -30.434 -18.917 29.776  1   47.64  ? 243 LEU D CA  1 
ATOM   603  C C   . LEU A 1 73  ? -30.43  -19.212 28.266  1   46.2   ? 243 LEU D C   1 
ATOM   604  O O   . LEU A 1 73  ? -29.828 -20.198 27.845  1   48.08  ? 243 LEU D O   1 
ATOM   605  C CB  . LEU A 1 73  ? -31.262 -19.944 30.554  1   48.44  ? 243 LEU D CB  1 
ATOM   606  C CG  . LEU A 1 73  ? -31.194 -19.839 32.082  1   48.81  ? 243 LEU D CG  1 
ATOM   607  C CD1 . LEU A 1 73  ? -32.197 -20.782 32.734  1   47.63  ? 243 LEU D CD1 1 
ATOM   608  C CD2 . LEU A 1 73  ? -29.778 -20.115 32.572  1   48.78  ? 243 LEU D CD2 1 
ATOM   609  N N   . SER A 1 74  ? -31.086 -18.376 27.455  1   43.59  ? 244 SER D N   1 
ATOM   610  C CA  . SER A 1 74  ? -30.96  -18.488 26.006  1   48.17  ? 244 SER D CA  1 
ATOM   611  C C   . SER A 1 74  ? -29.635 -17.934 25.493  1   46.82  ? 244 SER D C   1 
ATOM   612  O O   . SER A 1 74  ? -29.266 -18.252 24.37   1   46.64  ? 244 SER D O   1 
ATOM   613  C CB  . SER A 1 74  ? -32.109 -17.825 25.274  1   48.94  ? 244 SER D CB  1 
ATOM   614  O OG  . SER A 1 74  ? -33.347 -18.397 25.672  1   48.34  ? 244 SER D OG  1 
ATOM   615  N N   . SER A 1 75  ? -28.96  -17.102 26.302  1   48.52  ? 245 SER D N   1 
ATOM   616  C CA  . SER A 1 75  ? -27.751 -16.383 25.914  1   51.26  ? 245 SER D CA  1 
ATOM   617  C C   . SER A 1 75  ? -26.526 -16.844 26.711  1   49.39  ? 245 SER D C   1 
ATOM   618  O O   . SER A 1 75  ? -25.402 -16.728 26.226  1   51.61  ? 245 SER D O   1 
ATOM   619  C CB  . SER A 1 75  ? -27.919 -14.872 26.052  1   55.5   ? 245 SER D CB  1 
ATOM   620  O OG  . SER A 1 75  ? -29.256 -14.456 25.785  1   64.09  ? 245 SER D OG  1 
ATOM   621  N N   . MET A 1 76  ? -26.718 -17.347 27.934  1   46.73  ? 246 MET D N   1 
ATOM   622  C CA  . MET A 1 76  ? -25.592 -17.562 28.841  1   46.8   ? 246 MET D CA  1 
ATOM   623  C C   . MET A 1 76  ? -25.597 -19     29.356  1   48.82  ? 246 MET D C   1 
ATOM   624  O O   . MET A 1 76  ? -26.624 -19.478 29.855  1   47.78  ? 246 MET D O   1 
ATOM   625  C CB  . MET A 1 76  ? -25.687 -16.62  30.048  1   45.28  ? 246 MET D CB  1 
ATOM   626  C CG  . MET A 1 76  ? -25.838 -15.147 29.677  1   45.71  ? 246 MET D CG  1 
ATOM   627  S SD  . MET A 1 76  ? -24.28  -14.401 29.162  1   51.42  ? 246 MET D SD  1 
ATOM   628  C CE  . MET A 1 76  ? -23.44  -14.504 30.75   1   44.97  ? 246 MET D CE  1 
ATOM   629  N N   . SER A 1 77  ? -24.46  -19.7   29.222  1   48.16  ? 247 SER D N   1 
ATOM   630  C CA  . SER A 1 77  ? -24.32  -20.992 29.881  1   49.08  ? 247 SER D CA  1 
ATOM   631  C C   . SER A 1 77  ? -24.274 -20.735 31.381  1   48.16  ? 247 SER D C   1 
ATOM   632  O O   . SER A 1 77  ? -23.604 -19.804 31.801  1   52.99  ? 247 SER D O   1 
ATOM   633  C CB  . SER A 1 77  ? -23.056 -21.733 29.456  1   51.06  ? 247 SER D CB  1 
ATOM   634  O OG  . SER A 1 77  ? -23.004 -21.93  28.048  1   56.24  ? 247 SER D OG  1 
ATOM   635  N N   . VAL A 1 78  ? -24.945 -21.565 32.185  1   46.95  ? 248 VAL D N   1 
ATOM   636  C CA  . VAL A 1 78  ? -24.96  -21.392 33.631  1   46.63  ? 248 VAL D CA  1 
ATOM   637  C C   . VAL A 1 78  ? -24.768 -22.746 34.305  1   47.93  ? 248 VAL D C   1 
ATOM   638  O O   . VAL A 1 78  ? -25.386 -23.728 33.902  1   50.68  ? 248 VAL D O   1 
ATOM   639  C CB  . VAL A 1 78  ? -26.267 -20.712 34.093  1   45.71  ? 248 VAL D CB  1 
ATOM   640  C CG1 . VAL A 1 78  ? -26.397 -20.707 35.618  1   43.6   ? 248 VAL D CG1 1 
ATOM   641  C CG2 . VAL A 1 78  ? -26.379 -19.298 33.532  1   40.65  ? 248 VAL D CG2 1 
ATOM   642  N N   . LEU A 1 79  ? -23.912 -22.793 35.332  1   49.29  ? 249 LEU D N   1 
ATOM   643  C CA  . LEU A 1 79  ? -23.707 -24.026 36.075  1   49.76  ? 249 LEU D CA  1 
ATOM   644  C C   . LEU A 1 79  ? -24.853 -24.222 37.056  1   49.14  ? 249 LEU D C   1 
ATOM   645  O O   . LEU A 1 79  ? -25.477 -23.264 37.501  1   49.86  ? 249 LEU D O   1 
ATOM   646  C CB  . LEU A 1 79  ? -22.371 -24.025 36.801  1   49.33  ? 249 LEU D CB  1 
ATOM   647  C CG  . LEU A 1 79  ? -21.151 -24.004 35.886  1   53.04  ? 249 LEU D CG  1 
ATOM   648  C CD1 . LEU A 1 79  ? -19.892 -24.357 36.686  1   51.8   ? 249 LEU D CD1 1 
ATOM   649  C CD2 . LEU A 1 79  ? -21.342 -24.929 34.67   1   51.8   ? 249 LEU D CD2 1 
ATOM   650  N N   . ARG A 1 80  ? -25.058 -25.473 37.446  1   51.25  ? 250 ARG D N   1 
ATOM   651  C CA  . ARG A 1 80  ? -26.167 -25.846 38.302  1   52.91  ? 250 ARG D CA  1 
ATOM   652  C C   . ARG A 1 80  ? -26.157 -25.035 39.595  1   52.69  ? 250 ARG D C   1 
ATOM   653  O O   . ARG A 1 80  ? -27.215 -24.606 40.055  1   55     ? 250 ARG D O   1 
ATOM   654  C CB  . ARG A 1 80  ? -26.079 -27.34  38.605  1   55.27  ? 250 ARG D CB  1 
ATOM   655  C CG  . ARG A 1 80  ? -27.284 -27.831 39.389  1   58.72  ? 250 ARG D CG  1 
ATOM   656  C CD  . ARG A 1 80  ? -27.129 -29.321 39.571  1   64.06  ? 250 ARG D CD  1 
ATOM   657  N NE  . ARG A 1 80  ? -25.911 -29.656 40.324  1   64.58  ? 250 ARG D NE  1 
ATOM   658  C CZ  . ARG A 1 80  ? -25.359 -30.865 40.311  1   65.5   ? 250 ARG D CZ  1 
ATOM   659  N NH1 . ARG A 1 80  ? -25.803 -31.806 39.48   1   66.97  ? 250 ARG D NH1 1 
ATOM   660  N NH2 . ARG A 1 80  ? -24.338 -31.113 41.11   1   66.26  ? 250 ARG D NH2 1 
ATOM   661  N N   . GLY A 1 81  ? -24.969 -24.825 40.173  1   53.07  ? 251 GLY D N   1 
ATOM   662  C CA  . GLY A 1 81  ? -24.857 -24.123 41.443  1   51.35  ? 251 GLY D CA  1 
ATOM   663  C C   . GLY A 1 81  ? -25.243 -22.644 41.366  1   52.08  ? 251 GLY D C   1 
ATOM   664  O O   . GLY A 1 81  ? -25.426 -21.997 42.405  1   51.96  ? 251 GLY D O   1 
ATOM   665  N N   . LYS A 1 82  ? -25.349 -22.103 40.138  1   49.06  ? 252 LYS D N   1 
ATOM   666  C CA  . LYS A 1 82  ? -25.655 -20.689 39.972  1   45.18  ? 252 LYS D CA  1 
ATOM   667  C C   . LYS A 1 82  ? -27.057 -20.491 39.409  1   43.1   ? 252 LYS D C   1 
ATOM   668  O O   . LYS A 1 82  ? -27.5   -19.352 39.307  1   41.89  ? 252 LYS D O   1 
ATOM   669  C CB  . LYS A 1 82  ? -24.618 -19.969 39.103  1   43.41  ? 252 LYS D CB  1 
ATOM   670  C CG  . LYS A 1 82  ? -23.193 -20.007 39.691  1   44.23  ? 252 LYS D CG  1 
ATOM   671  C CD  . LYS A 1 82  ? -23.153 -19.094 40.904  1   43.31  ? 252 LYS D CD  1 
ATOM   672  C CE  . LYS A 1 82  ? -21.828 -18.648 41.397  1   43.56  ? 252 LYS D CE  1 
ATOM   673  N NZ  . LYS A 1 82  ? -21.22  -19.88  41.888  1   48.46  ? 252 LYS D NZ  1 
ATOM   674  N N   . LEU A 1 83  ? -27.739 -21.583 39.055  1   43.04  ? 253 LEU D N   1 
ATOM   675  C CA  . LEU A 1 83  ? -29.092 -21.496 38.523  1   44.93  ? 253 LEU D CA  1 
ATOM   676  C C   . LEU A 1 83  ? -29.996 -20.7   39.462  1   44.98  ? 253 LEU D C   1 
ATOM   677  O O   . LEU A 1 83  ? -30.808 -19.891 39.018  1   46.51  ? 253 LEU D O   1 
ATOM   678  C CB  . LEU A 1 83  ? -29.669 -22.897 38.327  1   48.64  ? 253 LEU D CB  1 
ATOM   679  C CG  . LEU A 1 83  ? -31.092 -22.934 37.752  1   50.68  ? 253 LEU D CG  1 
ATOM   680  C CD1 . LEU A 1 83  ? -31.25  -22.203 36.415  1   45.58  ? 253 LEU D CD1 1 
ATOM   681  C CD2 . LEU A 1 83  ? -31.528 -24.38  37.596  1   53.4   ? 253 LEU D CD2 1 
ATOM   682  N N   . GLN A 1 84  ? -29.876 -20.955 40.764  1   45.03  ? 254 GLN D N   1 
ATOM   683  C CA  . GLN A 1 84  ? -30.734 -20.269 41.708  1   46.44  ? 254 GLN D CA  1 
ATOM   684  C C   . GLN A 1 84  ? -30.358 -18.789 41.782  1   46.33  ? 254 GLN D C   1 
ATOM   685  O O   . GLN A 1 84  ? -31.219 -17.937 42.02   1   45.19  ? 254 GLN D O   1 
ATOM   686  C CB  . GLN A 1 84  ? -30.727 -20.947 43.075  1   48.84  ? 254 GLN D CB  1 
ATOM   687  C CG  . GLN A 1 84  ? -31.824 -20.414 43.992  1   50.25  ? 254 GLN D CG  1 
ATOM   688  C CD  . GLN A 1 84  ? -31.975 -21.166 45.295  1   52.91  ? 254 GLN D CD  1 
ATOM   689  O OE1 . GLN A 1 84  ? -32.939 -20.944 46.03   1   55.59  ? 254 GLN D OE1 1 
ATOM   690  N NE2 . GLN A 1 84  ? -31.042 -22.06  45.596  1   52.77  ? 254 GLN D NE2 1 
ATOM   691  N N   . LEU A 1 85  ? -29.074 -18.483 41.565  1   43.35  ? 255 LEU D N   1 
ATOM   692  C CA  . LEU A 1 85  ? -28.646 -17.098 41.603  1   43.33  ? 255 LEU D CA  1 
ATOM   693  C C   . LEU A 1 85  ? -29.331 -16.323 40.484  1   43.83  ? 255 LEU D C   1 
ATOM   694  O O   . LEU A 1 85  ? -29.852 -15.244 40.701  1   47.8   ? 255 LEU D O   1 
ATOM   695  C CB  . LEU A 1 85  ? -27.125 -16.992 41.511  1   44.04  ? 255 LEU D CB  1 
ATOM   696  C CG  . LEU A 1 85  ? -26.535 -15.589 41.683  1   43.12  ? 255 LEU D CG  1 
ATOM   697  C CD1 . LEU A 1 85  ? -27.012 -14.898 42.983  1   42.3   ? 255 LEU D CD1 1 
ATOM   698  C CD2 . LEU A 1 85  ? -25.035 -15.717 41.668  1   41.59  ? 255 LEU D CD2 1 
ATOM   699  N N   . VAL A 1 86  ? -29.33  -16.876 39.27   1   46     ? 256 VAL D N   1 
ATOM   700  C CA  . VAL A 1 86  ? -30.031 -16.263 38.154  1   43.99  ? 256 VAL D CA  1 
ATOM   701  C C   . VAL A 1 86  ? -31.518 -16.061 38.507  1   46.34  ? 256 VAL D C   1 
ATOM   702  O O   . VAL A 1 86  ? -32.096 -15.007 38.248  1   45.53  ? 256 VAL D O   1 
ATOM   703  C CB  . VAL A 1 86  ? -29.877 -17.136 36.896  1   41.93  ? 256 VAL D CB  1 
ATOM   704  C CG1 . VAL A 1 86  ? -30.763 -16.603 35.769  1   38.23  ? 256 VAL D CG1 1 
ATOM   705  C CG2 . VAL A 1 86  ? -28.415 -17.236 36.468  1   41.42  ? 256 VAL D CG2 1 
ATOM   706  N N   . GLY A 1 87  ? -32.148 -17.07  39.124  1   47.27  ? 257 GLY D N   1 
ATOM   707  C CA  . GLY A 1 87  ? -33.568 -16.998 39.447  1   45.44  ? 257 GLY D CA  1 
ATOM   708  C C   . GLY A 1 87  ? -33.892 -15.92  40.485  1   44.31  ? 257 GLY D C   1 
ATOM   709  O O   . GLY A 1 87  ? -34.913 -15.242 40.383  1   43.21  ? 257 GLY D O   1 
ATOM   710  N N   . THR A 1 88  ? -33.005 -15.744 41.471  1   43.49  ? 258 THR D N   1 
ATOM   711  C CA  . THR A 1 88  ? -33.218 -14.792 42.548  1   42.93  ? 258 THR D CA  1 
ATOM   712  C C   . THR A 1 88  ? -33.139 -13.387 41.966  1   42.58  ? 258 THR D C   1 
ATOM   713  O O   . THR A 1 88  ? -33.937 -12.519 42.334  1   44.69  ? 258 THR D O   1 
ATOM   714  C CB  . THR A 1 88  ? -32.205 -15.021 43.671  1   43.1   ? 258 THR D CB  1 
ATOM   715  O OG1 . THR A 1 88  ? -32.408 -16.371 44.085  1   45.17  ? 258 THR D OG1 1 
ATOM   716  C CG2 . THR A 1 88  ? -32.454 -14.109 44.851  1   44.31  ? 258 THR D CG2 1 
ATOM   717  N N   . ALA A 1 89  ? -32.163 -13.186 41.07   1   41.45  ? 259 ALA D N   1 
ATOM   718  C CA  . ALA A 1 89  ? -31.915 -11.894 40.444  1   39.89  ? 259 ALA D CA  1 
ATOM   719  C C   . ALA A 1 89  ? -33.078 -11.546 39.523  1   39.53  ? 259 ALA D C   1 
ATOM   720  O O   . ALA A 1 89  ? -33.481 -10.387 39.468  1   43.53  ? 259 ALA D O   1 
ATOM   721  C CB  . ALA A 1 89  ? -30.613 -11.905 39.683  1   36.79  ? 259 ALA D CB  1 
ATOM   722  N N   . ALA A 1 90  ? -33.59  -12.527 38.781  1   39.33  ? 260 ALA D N   1 
ATOM   723  C CA  . ALA A 1 90  ? -34.735 -12.282 37.904  1   40.91  ? 260 ALA D CA  1 
ATOM   724  C C   . ALA A 1 90  ? -35.97  -11.927 38.725  1   42.35  ? 260 ALA D C   1 
ATOM   725  O O   . ALA A 1 90  ? -36.686 -10.982 38.397  1   44.41  ? 260 ALA D O   1 
ATOM   726  C CB  . ALA A 1 90  ? -35.003 -13.472 37.03   1   37.91  ? 260 ALA D CB  1 
ATOM   727  N N   . MET A 1 91  ? -36.195 -12.659 39.821  1   46.08  ? 261 MET D N   1 
ATOM   728  C CA  . MET A 1 91  ? -37.32  -12.365 40.701  1   42.42  ? 261 MET D CA  1 
ATOM   729  C C   . MET A 1 91  ? -37.176 -10.947 41.238  1   45.09  ? 261 MET D C   1 
ATOM   730  O O   . MET A 1 91  ? -38.164 -10.201 41.278  1   48.47  ? 261 MET D O   1 
ATOM   731  C CB  . MET A 1 91  ? -37.397 -13.342 41.873  1   42.65  ? 261 MET D CB  1 
ATOM   732  C CG  . MET A 1 91  ? -38.813 -13.406 42.493  1   49.49  ? 261 MET D CG  1 
ATOM   733  S SD  . MET A 1 91  ? -40.13  -13.832 41.321  1   51.78  ? 261 MET D SD  1 
ATOM   734  C CE  . MET A 1 91  ? -41.246 -14.58  42.508  1   50.4   ? 261 MET D CE  1 
ATOM   735  N N   . LEU A 1 92  ? -35.94  -10.575 41.636  1   41.31  ? 262 LEU D N   1 
ATOM   736  C CA  . LEU A 1 92  ? -35.699 -9.259  42.192  1   39.32  ? 262 LEU D CA  1 
ATOM   737  C C   . LEU A 1 92  ? -36.087 -8.184  41.166  1   38.43  ? 262 LEU D C   1 
ATOM   738  O O   . LEU A 1 92  ? -36.753 -7.197  41.501  1   38.42  ? 262 LEU D O   1 
ATOM   739  C CB  . LEU A 1 92  ? -34.238 -9.16   42.629  1   38.08  ? 262 LEU D CB  1 
ATOM   740  C CG  . LEU A 1 92  ? -33.764 -7.763  43.038  1   37.73  ? 262 LEU D CG  1 
ATOM   741  C CD1 . LEU A 1 92  ? -34.568 -7.205  44.203  1   35.98  ? 262 LEU D CD1 1 
ATOM   742  C CD2 . LEU A 1 92  ? -32.278 -7.759  43.401  1   37.39  ? 262 LEU D CD2 1 
ATOM   743  N N   . LEU A 1 93  ? -35.644 -8.373  39.922  1   36.59  ? 263 LEU D N   1 
ATOM   744  C CA  . LEU A 1 93  ? -35.868 -7.421  38.848  1   37.21  ? 263 LEU D CA  1 
ATOM   745  C C   . LEU A 1 93  ? -37.354 -7.343  38.5    1   38.55  ? 263 LEU D C   1 
ATOM   746  O O   . LEU A 1 93  ? -37.864 -6.24   38.289  1   42.8   ? 263 LEU D O   1 
ATOM   747  C CB  . LEU A 1 93  ? -35.029 -7.818  37.634  1   37.21  ? 263 LEU D CB  1 
ATOM   748  C CG  . LEU A 1 93  ? -33.532 -7.482  37.692  1   39.46  ? 263 LEU D CG  1 
ATOM   749  C CD1 . LEU A 1 93  ? -32.788 -8.179  36.565  1   37.49  ? 263 LEU D CD1 1 
ATOM   750  C CD2 . LEU A 1 93  ? -33.271 -5.987  37.615  1   38.55  ? 263 LEU D CD2 1 
ATOM   751  N N   . ALA A 1 94  ? -38.031 -8.498  38.417  1   36.76  ? 264 ALA D N   1 
ATOM   752  C CA  . ALA A 1 94  ? -39.461 -8.519  38.144  1   37.18  ? 264 ALA D CA  1 
ATOM   753  C C   . ALA A 1 94  ? -40.21  -7.719  39.205  1   39.63  ? 264 ALA D C   1 
ATOM   754  O O   . ALA A 1 94  ? -41.068 -6.9    38.889  1   41.82  ? 264 ALA D O   1 
ATOM   755  C CB  . ALA A 1 94  ? -39.964 -9.923  38.067  1   35.21  ? 264 ALA D CB  1 
ATOM   756  N N   . SER A 1 95  ? -39.84  -7.92   40.468  1   40.1   ? 265 SER D N   1 
ATOM   757  C CA  . SER A 1 95  ? -40.44  -7.196  41.575  1   40.71  ? 265 SER D CA  1 
ATOM   758  C C   . SER A 1 95  ? -40.222 -5.693  41.423  1   43.9   ? 265 SER D C   1 
ATOM   759  O O   . SER A 1 95  ? -41.159 -4.903  41.619  1   45.89  ? 265 SER D O   1 
ATOM   760  C CB  . SER A 1 95  ? -39.885 -7.715  42.881  1   40.59  ? 265 SER D CB  1 
ATOM   761  O OG  . SER A 1 95  ? -40.096 -9.123  42.962  1   41.15  ? 265 SER D OG  1 
ATOM   762  N N   . LYS A 1 96  ? -38.971 -5.288  41.126  1   41.05  ? 266 LYS D N   1 
ATOM   763  C CA  . LYS A 1 96  ? -38.722 -3.865  41.004  1   41.06  ? 266 LYS D CA  1 
ATOM   764  C C   . LYS A 1 96  ? -39.54  -3.285  39.849  1   40.18  ? 266 LYS D C   1 
ATOM   765  O O   . LYS A 1 96  ? -39.966 -2.128  39.92   1   40.98  ? 266 LYS D O   1 
ATOM   766  C CB  . LYS A 1 96  ? -37.24  -3.554  40.779  1   40.97  ? 266 LYS D CB  1 
ATOM   767  C CG  . LYS A 1 96  ? -36.371 -3.68   42.035  1   40.07  ? 266 LYS D CG  1 
ATOM   768  C CD  . LYS A 1 96  ? -34.902 -3.441  41.749  1   37.49  ? 266 LYS D CD  1 
ATOM   769  C CE  . LYS A 1 96  ? -34.048 -3.402  42.988  1   38.92  ? 266 LYS D CE  1 
ATOM   770  N NZ  . LYS A 1 96  ? -32.658 -3.278  42.541  1   36.74  ? 266 LYS D NZ  1 
ATOM   771  N N   . PHE A 1 97  ? -39.689 -4.058  38.772  1   37.14  ? 267 PHE D N   1 
ATOM   772  C CA  . PHE A 1 97  ? -40.416 -3.569  37.611  1   39.84  ? 267 PHE D CA  1 
ATOM   773  C C   . PHE A 1 97  ? -41.906 -3.443  37.935  1   41.14  ? 267 PHE D C   1 
ATOM   774  O O   . PHE A 1 97  ? -42.461 -2.374  37.738  1   40.34  ? 267 PHE D O   1 
ATOM   775  C CB  . PHE A 1 97  ? -40.19  -4.452  36.385  1   38.96  ? 267 PHE D CB  1 
ATOM   776  C CG  . PHE A 1 97  ? -40.928 -4.014  35.135  1   39.8   ? 267 PHE D CG  1 
ATOM   777  C CD1 . PHE A 1 97  ? -40.362 -3.108  34.233  1   40.54  ? 267 PHE D CD1 1 
ATOM   778  C CD2 . PHE A 1 97  ? -42.201 -4.523  34.865  1   41.53  ? 267 PHE D CD2 1 
ATOM   779  C CE1 . PHE A 1 97  ? -41.043 -2.747  33.066  1   40.99  ? 267 PHE D CE1 1 
ATOM   780  C CE2 . PHE A 1 97  ? -42.893 -4.167  33.699  1   40.26  ? 267 PHE D CE2 1 
ATOM   781  C CZ  . PHE A 1 97  ? -42.318 -3.275  32.803  1   41.83  ? 267 PHE D CZ  1 
ATOM   782  N N   . GLU A 1 98  ? -42.493 -4.498  38.521  1   42.9   ? 268 GLU D N   1 
ATOM   783  C CA  . GLU A 1 98  ? -43.936 -4.698  38.564  1   44.81  ? 268 GLU D CA  1 
ATOM   784  C C   . GLU A 1 98  ? -44.556 -4.268  39.896  1   46.69  ? 268 GLU D C   1 
ATOM   785  O O   . GLU A 1 98  ? -45.678 -3.784  39.89   1   50.94  ? 268 GLU D O   1 
ATOM   786  C CB  . GLU A 1 98  ? -44.32  -6.15   38.269  1   43.17  ? 268 GLU D CB  1 
ATOM   787  C CG  . GLU A 1 98  ? -45.807 -6.325  37.945  1   46.84  ? 268 GLU D CG  1 
ATOM   788  C CD  . GLU A 1 98  ? -46.3   -5.537  36.744  1   46.52  ? 268 GLU D CD  1 
ATOM   789  O OE1 . GLU A 1 98  ? -45.48  -5.218  35.839  1   46.63  ? 268 GLU D OE1 1 
ATOM   790  O OE2 . GLU A 1 98  ? -47.509 -5.213  36.72   1   47.11  ? 268 GLU D OE2 1 
ATOM   791  N N   . GLU A 1 99  ? -43.858 -4.418  41.033  1   48.72  ? 269 GLU D N   1 
ATOM   792  C CA  . GLU A 1 99  ? -44.506 -4.302  42.345  1   45.96  ? 269 GLU D CA  1 
ATOM   793  C C   . GLU A 1 99  ? -44.518 -2.864  42.847  1   47.6   ? 269 GLU D C   1 
ATOM   794  O O   . GLU A 1 99  ? -43.541 -2.128  42.707  1   49.33  ? 269 GLU D O   1 
ATOM   795  C CB  . GLU A 1 99  ? -43.807 -5.111  43.438  1   42.84  ? 269 GLU D CB  1 
ATOM   796  C CG  . GLU A 1 99  ? -43.831 -6.616  43.192  1   42.76  ? 269 GLU D CG  1 
ATOM   797  C CD  . GLU A 1 99  ? -45.171 -7.271  43.46   1   45.52  ? 269 GLU D CD  1 
ATOM   798  O OE1 . GLU A 1 99  ? -45.817 -6.929  44.477  1   48.5   ? 269 GLU D OE1 1 
ATOM   799  O OE2 . GLU A 1 99  ? -45.561 -8.142  42.671  1   46.3   ? 269 GLU D OE2 1 
ATOM   800  N N   . ILE A 1 100 ? -45.61  -2.502  43.525  1   49.47  ? 270 ILE D N   1 
ATOM   801  C CA  . ILE A 1 100 ? -45.671 -1.231  44.229  1   49.66  ? 270 ILE D CA  1 
ATOM   802  C C   . ILE A 1 100 ? -44.628 -1.209  45.353  1   51.31  ? 270 ILE D C   1 
ATOM   803  O O   . ILE A 1 100 ? -43.968 -0.191  45.558  1   52.04  ? 270 ILE D O   1 
ATOM   804  C CB  . ILE A 1 100 ? -47.072 -0.969  44.807  1   49.77  ? 270 ILE D CB  1 
ATOM   805  C CG1 . ILE A 1 100 ? -48.175 -0.957  43.742  1   49.91  ? 270 ILE D CG1 1 
ATOM   806  C CG2 . ILE A 1 100 ? -47.074 0.312   45.643  1   48.59  ? 270 ILE D CG2 1 
ATOM   807  C CD1 . ILE A 1 100 ? -49.567 -0.795  44.345  1   48.27  ? 270 ILE D CD1 1 
ATOM   808  N N   . TYR A 1 101 ? -44.558 -2.307  46.123  1   51.81  ? 271 TYR D N   1 
ATOM   809  C CA  . TYR A 1 101 ? -43.684 -2.396  47.28   1   52.54  ? 271 TYR D CA  1 
ATOM   810  C C   . TYR A 1 101 ? -42.81  -3.638  47.146  1   51.81  ? 271 TYR D C   1 
ATOM   811  O O   . TYR A 1 101 ? -43.033 -4.627  47.84   1   53.37  ? 271 TYR D O   1 
ATOM   812  C CB  . TYR A 1 101 ? -44.499 -2.507  48.568  1   56.18  ? 271 TYR D CB  1 
ATOM   813  C CG  . TYR A 1 101 ? -45.401 -1.312  48.836  1   62.08  ? 271 TYR D CG  1 
ATOM   814  C CD1 . TYR A 1 101 ? -44.899 -0.129  49.382  1   60     ? 271 TYR D CD1 1 
ATOM   815  C CD2 . TYR A 1 101 ? -46.77  -1.379  48.542  1   65.02  ? 271 TYR D CD2 1 
ATOM   816  C CE1 . TYR A 1 101 ? -45.743 0.949   49.627  1   63.95  ? 271 TYR D CE1 1 
ATOM   817  C CE2 . TYR A 1 101 ? -47.622 -0.311  48.804  1   65.73  ? 271 TYR D CE2 1 
ATOM   818  C CZ  . TYR A 1 101 ? -47.1   0.861   49.332  1   66.71  ? 271 TYR D CZ  1 
ATOM   819  O OH  . TYR A 1 101 ? -47.947 1.915   49.558  1   73.64  ? 271 TYR D OH  1 
ATOM   820  N N   . PRO A 1 102 ? -41.767 -3.638  46.275  1   48.93  ? 272 PRO D N   1 
ATOM   821  C CA  . PRO A 1 102 ? -40.959 -4.849  46.08   1   44.28  ? 272 PRO D CA  1 
ATOM   822  C C   . PRO A 1 102 ? -40.338 -5.198  47.431  1   43.72  ? 272 PRO D C   1 
ATOM   823  O O   . PRO A 1 102 ? -40.109 -4.317  48.256  1   43.37  ? 272 PRO D O   1 
ATOM   824  C CB  . PRO A 1 102 ? -39.884 -4.393  45.083  1   42.75  ? 272 PRO D CB  1 
ATOM   825  C CG  . PRO A 1 102 ? -39.881 -2.871  45.157  1   43.73  ? 272 PRO D CG  1 
ATOM   826  C CD  . PRO A 1 102 ? -41.293 -2.471  45.509  1   44.78  ? 272 PRO D CD  1 
ATOM   827  N N   . PRO A 1 103 ? -40.021 -6.476  47.713  1   44.01  ? 273 PRO D N   1 
ATOM   828  C CA  . PRO A 1 103 ? -39.162 -6.799  48.85   1   45.8   ? 273 PRO D CA  1 
ATOM   829  C C   . PRO A 1 103 ? -37.768 -6.201  48.651  1   47.27  ? 273 PRO D C   1 
ATOM   830  O O   . PRO A 1 103 ? -37.28  -6.055  47.528  1   46.12  ? 273 PRO D O   1 
ATOM   831  C CB  . PRO A 1 103 ? -39.129 -8.328  48.905  1   44.56  ? 273 PRO D CB  1 
ATOM   832  C CG  . PRO A 1 103 ? -40.201 -8.776  47.938  1   44.81  ? 273 PRO D CG  1 
ATOM   833  C CD  . PRO A 1 103 ? -40.44  -7.661  46.951  1   43.13  ? 273 PRO D CD  1 
ATOM   834  N N   . GLU A 1 104 ? -37.133 -5.869  49.778  1   50.05  ? 274 GLU D N   1 
ATOM   835  C CA  . GLU A 1 104 ? -35.748 -5.445  49.81   1   50.61  ? 274 GLU D CA  1 
ATOM   836  C C   . GLU A 1 104 ? -34.85  -6.57   49.338  1   47.3   ? 274 GLU D C   1 
ATOM   837  O O   . GLU A 1 104 ? -35.232 -7.737  49.424  1   44.46  ? 274 GLU D O   1 
ATOM   838  C CB  . GLU A 1 104 ? -35.382 -5.114  51.253  1   56.83  ? 274 GLU D CB  1 
ATOM   839  C CG  . GLU A 1 104 ? -35.914 -3.747  51.665  1   66.42  ? 274 GLU D CG  1 
ATOM   840  C CD  . GLU A 1 104 ? -35.678 -3.531  53.144  1   78.73  ? 274 GLU D CD  1 
ATOM   841  O OE1 . GLU A 1 104 ? -35.757 -2.361  53.593  1   89.78  ? 274 GLU D OE1 1 
ATOM   842  O OE2 . GLU A 1 104 ? -35.426 -4.542  53.844  1   78.98  ? 274 GLU D OE2 1 
ATOM   843  N N   . VAL A 1 105 ? -33.655 -6.187  48.86   1   46.39  ? 275 VAL D N   1 
ATOM   844  C CA  . VAL A 1 105 ? -32.66  -7.163  48.422  1   46.78  ? 275 VAL D CA  1 
ATOM   845  C C   . VAL A 1 105 ? -32.354 -8.198  49.521  1   45.98  ? 275 VAL D C   1 
ATOM   846  O O   . VAL A 1 105 ? -32.222 -9.4    49.262  1   45.11  ? 275 VAL D O   1 
ATOM   847  C CB  . VAL A 1 105 ? -31.392 -6.493  47.845  1   46.07  ? 275 VAL D CB  1 
ATOM   848  C CG1 . VAL A 1 105 ? -30.362 -7.54   47.427  1   43.62  ? 275 VAL D CG1 1 
ATOM   849  C CG2 . VAL A 1 105 ? -31.732 -5.56   46.681  1   42.95  ? 275 VAL D CG2 1 
ATOM   850  N N   . ALA A 1 106 ? -32.273 -7.722  50.766  1   47.77  ? 276 ALA D N   1 
ATOM   851  C CA  . ALA A 1 106 ? -31.963 -8.586  51.891  1   50.14  ? 276 ALA D CA  1 
ATOM   852  C C   . ALA A 1 106 ? -32.899 -9.795  51.93   1   51.41  ? 276 ALA D C   1 
ATOM   853  O O   . ALA A 1 106 ? -32.484 -10.9   52.276  1   52.32  ? 276 ALA D O   1 
ATOM   854  C CB  . ALA A 1 106 ? -32.044 -7.789  53.163  1   50.49  ? 276 ALA D CB  1 
ATOM   855  N N   . GLU A 1 107 ? -34.174 -9.556  51.615  1   51.52  ? 277 GLU D N   1 
ATOM   856  C CA  . GLU A 1 107 ? -35.184 -10.6   51.652  1   53.3   ? 277 GLU D CA  1 
ATOM   857  C C   . GLU A 1 107 ? -34.901 -11.592 50.526  1   51.35  ? 277 GLU D C   1 
ATOM   858  O O   . GLU A 1 107 ? -35.146 -12.778 50.656  1   54.34  ? 277 GLU D O   1 
ATOM   859  C CB  . GLU A 1 107 ? -36.599 -10.002 51.635  1   56.6   ? 277 GLU D CB  1 
ATOM   860  C CG  . GLU A 1 107 ? -37.066 -9.4    52.959  1   63.34  ? 277 GLU D CG  1 
ATOM   861  C CD  . GLU A 1 107 ? -37.102 -10.404 54.123  1   79.56  ? 277 GLU D CD  1 
ATOM   862  O OE1 . GLU A 1 107 ? -37.795 -11.471 54.053  1   80.38  ? 277 GLU D OE1 1 
ATOM   863  O OE2 . GLU A 1 107 ? -36.405 -10.13  55.135  1   86.14  ? 277 GLU D OE2 1 
ATOM   864  N N   . PHE A 1 108 ? -34.317 -11.125 49.424  1   51.46  ? 278 PHE D N   1 
ATOM   865  C CA  . PHE A 1 108 ? -34.005 -12.013 48.317  1   49.32  ? 278 PHE D CA  1 
ATOM   866  C C   . PHE A 1 108 ? -32.818 -12.895 48.699  1   50.73  ? 278 PHE D C   1 
ATOM   867  O O   . PHE A 1 108 ? -32.668 -14.013 48.173  1   52.46  ? 278 PHE D O   1 
ATOM   868  C CB  . PHE A 1 108 ? -33.82  -11.236 47.002  1   44.77  ? 278 PHE D CB  1 
ATOM   869  C CG  . PHE A 1 108 ? -35.143 -10.82  46.379  1   43.81  ? 278 PHE D CG  1 
ATOM   870  C CD1 . PHE A 1 108 ? -35.907 -11.73  45.648  1   43.8   ? 278 PHE D CD1 1 
ATOM   871  C CD2 . PHE A 1 108 ? -35.679 -9.552  46.597  1   43.64  ? 278 PHE D CD2 1 
ATOM   872  C CE1 . PHE A 1 108 ? -37.147 -11.367 45.113  1   41.85  ? 278 PHE D CE1 1 
ATOM   873  C CE2 . PHE A 1 108 ? -36.922 -9.202  46.056  1   43.17  ? 278 PHE D CE2 1 
ATOM   874  C CZ  . PHE A 1 108 ? -37.652 -10.098 45.3    1   40.81  ? 278 PHE D CZ  1 
ATOM   875  N N   . VAL A 1 109 ? -31.957 -12.36  49.572  1   48.85  ? 279 VAL D N   1 
ATOM   876  C CA  . VAL A 1 109 ? -30.803 -13.116 50.032  1   51.38  ? 279 VAL D CA  1 
ATOM   877  C C   . VAL A 1 109 ? -31.264 -14.186 51.022  1   55.67  ? 279 VAL D C   1 
ATOM   878  O O   . VAL A 1 109 ? -30.816 -15.327 50.968  1   59.97  ? 279 VAL D O   1 
ATOM   879  C CB  . VAL A 1 109 ? -29.733 -12.229 50.697  1   50.85  ? 279 VAL D CB  1 
ATOM   880  C CG1 . VAL A 1 109 ? -28.576 -13.065 51.229  1   49.31  ? 279 VAL D CG1 1 
ATOM   881  C CG2 . VAL A 1 109 ? -29.203 -11.165 49.758  1   48.27  ? 279 VAL D CG2 1 
ATOM   882  N N   . TYR A 1 110 ? -32.105 -13.778 51.974  1   56.35  ? 280 TYR D N   1 
ATOM   883  C CA  . TYR A 1 110 ? -32.638 -14.662 52.992  1   59.63  ? 280 TYR D CA  1 
ATOM   884  C C   . TYR A 1 110 ? -33.263 -15.91  52.35   1   58.15  ? 280 TYR D C   1 
ATOM   885  O O   . TYR A 1 110 ? -33.033 -17.006 52.83   1   61.74  ? 280 TYR D O   1 
ATOM   886  C CB  . TYR A 1 110 ? -33.538 -13.831 53.912  1   62.6   ? 280 TYR D CB  1 
ATOM   887  C CG  . TYR A 1 110 ? -34.22  -14.656 54.992  1   75.71  ? 280 TYR D CG  1 
ATOM   888  C CD1 . TYR A 1 110 ? -33.587 -14.872 56.215  1   82.4   ? 280 TYR D CD1 1 
ATOM   889  C CD2 . TYR A 1 110 ? -35.48  -15.23  54.79   1   76.39  ? 280 TYR D CD2 1 
ATOM   890  C CE1 . TYR A 1 110 ? -34.199 -15.609 57.217  1   86.21  ? 280 TYR D CE1 1 
ATOM   891  C CE2 . TYR A 1 110 ? -36.084 -15.997 55.775  1   80.38  ? 280 TYR D CE2 1 
ATOM   892  C CZ  . TYR A 1 110 ? -35.442 -16.182 56.99   1   86.21  ? 280 TYR D CZ  1 
ATOM   893  O OH  . TYR A 1 110 ? -36.034 -16.936 57.965  1   90.58  ? 280 TYR D OH  1 
ATOM   894  N N   . ILE A 1 111 ? -34.048 -15.767 51.277  1   57.47  ? 281 ILE D N   1 
ATOM   895  C CA  . ILE A 1 111 ? -34.81  -16.884 50.715  1   61.2   ? 281 ILE D CA  1 
ATOM   896  C C   . ILE A 1 111 ? -33.917 -17.936 50.05   1   63.89  ? 281 ILE D C   1 
ATOM   897  O O   . ILE A 1 111 ? -34.419 -19.016 49.74   1   65.96  ? 281 ILE D O   1 
ATOM   898  C CB  . ILE A 1 111 ? -35.861 -16.424 49.691  1   59.86  ? 281 ILE D CB  1 
ATOM   899  C CG1 . ILE A 1 111 ? -35.217 -15.521 48.648  1   60.72  ? 281 ILE D CG1 1 
ATOM   900  C CG2 . ILE A 1 111 ? -37.061 -15.758 50.356  1   60.36  ? 281 ILE D CG2 1 
ATOM   901  C CD1 . ILE A 1 111 ? -36.027 -15.322 47.378  1   62.48  ? 281 ILE D CD1 1 
ATOM   902  N N   . THR A 1 112 ? -32.636 -17.621 49.773  1   62.22  ? 282 THR D N   1 
ATOM   903  C CA  . THR A 1 112 ? -31.719 -18.592 49.186  1   60.97  ? 282 THR D CA  1 
ATOM   904  C C   . THR A 1 112 ? -30.931 -19.303 50.272  1   67.13  ? 282 THR D C   1 
ATOM   905  O O   . THR A 1 112 ? -29.927 -19.931 49.926  1   71.37  ? 282 THR D O   1 
ATOM   906  C CB  . THR A 1 112 ? -30.732 -17.992 48.185  1   59.05  ? 282 THR D CB  1 
ATOM   907  O OG1 . THR A 1 112 ? -29.724 -17.281 48.907  1   59.96  ? 282 THR D OG1 1 
ATOM   908  C CG2 . THR A 1 112 ? -31.405 -17.132 47.135  1   54.06  ? 282 THR D CG2 1 
ATOM   909  N N   . ASP A 1 113 ? -31.363 -19.171 51.546  1   74.39  ? 283 ASP D N   1 
ATOM   910  C CA  . ASP A 1 113 ? -30.758 -19.814 52.712  1   82.35  ? 283 ASP D CA  1 
ATOM   911  C C   . ASP A 1 113 ? -29.314 -19.355 52.919  1   84.03  ? 283 ASP D C   1 
ATOM   912  O O   . ASP A 1 113 ? -28.513 -20.068 53.53   1   87.01  ? 283 ASP D O   1 
ATOM   913  C CB  . ASP A 1 113 ? -30.801 -21.336 52.615  1   95.22  ? 283 ASP D CB  1 
ATOM   914  C CG  . ASP A 1 113 ? -32.034 -22.012 53.193  1   102.63 ? 283 ASP D CG  1 
ATOM   915  O OD1 . ASP A 1 113 ? -33.149 -21.53  52.894  1   102.98 ? 283 ASP D OD1 1 
ATOM   916  O OD2 . ASP A 1 113 ? -31.85  -23.014 53.929  1   103.46 ? 283 ASP D OD2 1 
ATOM   917  N N   . ASP A 1 114 ? -28.979 -18.165 52.406  1   85.76  ? 284 ASP D N   1 
ATOM   918  C CA  . ASP A 1 114 ? -27.585 -17.755 52.307  1   92.19  ? 284 ASP D CA  1 
ATOM   919  C C   . ASP A 1 114 ? -26.739 -18.791 51.535  1   84.79  ? 284 ASP D C   1 
ATOM   920  O O   . ASP A 1 114 ? -25.602 -19.082 51.91   1   78.49  ? 284 ASP D O   1 
ATOM   921  C CB  . ASP A 1 114 ? -27.043 -17.326 53.669  1   109.92 ? 284 ASP D CB  1 
ATOM   922  C CG  . ASP A 1 114 ? -27.868 -16.32  54.471  1   111.15 ? 284 ASP D CG  1 
ATOM   923  O OD1 . ASP A 1 114 ? -28.944 -15.874 54.004  1   108.33 ? 284 ASP D OD1 1 
ATOM   924  O OD2 . ASP A 1 114 ? -27.42  -15.962 55.576  1   112.01 ? 284 ASP D OD2 1 
ATOM   925  N N   . THR A 1 115 ? -27.272 -19.34  50.429  1   73.46  ? 285 THR D N   1 
ATOM   926  C CA  . THR A 1 115 ? -26.415 -19.991 49.45   1   73.3   ? 285 THR D CA  1 
ATOM   927  C C   . THR A 1 115 ? -25.507 -18.91  48.835  1   70.97  ? 285 THR D C   1 
ATOM   928  O O   . THR A 1 115 ? -24.304 -19.109 48.676  1   72.7   ? 285 THR D O   1 
ATOM   929  C CB  . THR A 1 115 ? -27.247 -20.751 48.4    1   75.56  ? 285 THR D CB  1 
ATOM   930  O OG1 . THR A 1 115 ? -28.228 -21.603 48.978  1   74.4   ? 285 THR D OG1 1 
ATOM   931  C CG2 . THR A 1 115 ? -26.423 -21.654 47.497  1   71.17  ? 285 THR D CG2 1 
ATOM   932  N N   . TYR A 1 116 ? -26.093 -17.741 48.532  1   61.19  ? 286 TYR D N   1 
ATOM   933  C CA  . TYR A 1 116 ? -25.407 -16.637 47.882  1   59.36  ? 286 TYR D CA  1 
ATOM   934  C C   . TYR A 1 116 ? -25.302 -15.444 48.83   1   61.72  ? 286 TYR D C   1 
ATOM   935  O O   . TYR A 1 116 ? -26.178 -15.213 49.665  1   66     ? 286 TYR D O   1 
ATOM   936  C CB  . TYR A 1 116 ? -26.127 -16.22  46.59   1   55.36  ? 286 TYR D CB  1 
ATOM   937  C CG  . TYR A 1 116 ? -26.449 -17.399 45.684  1   55.12  ? 286 TYR D CG  1 
ATOM   938  C CD1 . TYR A 1 116 ? -25.43  -18.133 45.087  1   53.88  ? 286 TYR D CD1 1 
ATOM   939  C CD2 . TYR A 1 116 ? -27.761 -17.815 45.481  1   51.55  ? 286 TYR D CD2 1 
ATOM   940  C CE1 . TYR A 1 116 ? -25.703 -19.244 44.305  1   52.98  ? 286 TYR D CE1 1 
ATOM   941  C CE2 . TYR A 1 116 ? -28.043 -18.926 44.706  1   50.76  ? 286 TYR D CE2 1 
ATOM   942  C CZ  . TYR A 1 116 ? -27.016 -19.645 44.117  1   52.89  ? 286 TYR D CZ  1 
ATOM   943  O OH  . TYR A 1 116 ? -27.291 -20.735 43.327  1   56     ? 286 TYR D OH  1 
ATOM   944  N N   . THR A 1 117 ? -24.227 -14.662 48.673  1   58.34  ? 287 THR D N   1 
ATOM   945  C CA  . THR A 1 117 ? -24.103 -13.371 49.347  1   57.9   ? 287 THR D CA  1 
ATOM   946  C C   . THR A 1 117 ? -25.007 -12.331 48.679  1   55.51  ? 287 THR D C   1 
ATOM   947  O O   . THR A 1 117 ? -25.414 -12.47  47.514  1   52.34  ? 287 THR D O   1 
ATOM   948  C CB  . THR A 1 117 ? -22.647 -12.882 49.364  1   57.03  ? 287 THR D CB  1 
ATOM   949  O OG1 . THR A 1 117 ? -22.294 -12.413 48.061  1   53.61  ? 287 THR D OG1 1 
ATOM   950  C CG2 . THR A 1 117 ? -21.669 -13.972 49.767  1   56.42  ? 287 THR D CG2 1 
ATOM   951  N N   . LYS A 1 118 ? -25.21  -11.227 49.406  1   55.58  ? 288 LYS D N   1 
ATOM   952  C CA  . LYS A 1 118 ? -25.894 -10.062 48.868  1   56.38  ? 288 LYS D CA  1 
ATOM   953  C C   . LYS A 1 118 ? -25.185 -9.555  47.613  1   58.03  ? 288 LYS D C   1 
ATOM   954  O O   . LYS A 1 118 ? -25.852 -9.166  46.647  1   53.77  ? 288 LYS D O   1 
ATOM   955  C CB  . LYS A 1 118 ? -26.038 -8.969  49.928  1   54.93  ? 288 LYS D CB  1 
ATOM   956  C CG  . LYS A 1 118 ? -26.929 -7.831  49.484  1   55.55  ? 288 LYS D CG  1 
ATOM   957  C CD  . LYS A 1 118 ? -27.653 -7.109  50.625  1   60.66  ? 288 LYS D CD  1 
ATOM   958  C CE  . LYS A 1 118 ? -26.843 -6.162  51.448  1   58.73  ? 288 LYS D CE  1 
ATOM   959  N NZ  . LYS A 1 118 ? -27.705 -5.27   52.222  1   61.19  ? 288 LYS D NZ  1 
ATOM   960  N N   . LYS A 1 119 ? -23.842 -9.592  47.636  1   56.49  ? 289 LYS D N   1 
ATOM   961  C CA  . LYS A 1 119 ? -23.083 -8.997  46.551  1   53.52  ? 289 LYS D CA  1 
ATOM   962  C C   . LYS A 1 119 ? -23.286 -9.821  45.291  1   48.08  ? 289 LYS D C   1 
ATOM   963  O O   . LYS A 1 119 ? -23.34  -9.275  44.194  1   48.1   ? 289 LYS D O   1 
ATOM   964  C CB  . LYS A 1 119 ? -21.579 -8.837  46.783  1   55.33  ? 289 LYS D CB  1 
ATOM   965  C CG  . LYS A 1 119 ? -20.913 -8.067  45.636  1   62.96  ? 289 LYS D CG  1 
ATOM   966  C CD  . LYS A 1 119 ? -19.401 -8.208  45.45   1   69.47  ? 289 LYS D CD  1 
ATOM   967  C CE  . LYS A 1 119 ? -18.58  -7.903  46.671  1   70.84  ? 289 LYS D CE  1 
ATOM   968  N NZ  . LYS A 1 119 ? -17.127 -7.902  46.462  1   72.91  ? 289 LYS D NZ  1 
ATOM   969  N N   . GLN A 1 120 ? -23.37  -11.138 45.455  1   47.5   ? 290 GLN D N   1 
ATOM   970  C CA  . GLN A 1 120 ? -23.633 -12     44.312  1   47.41  ? 290 GLN D CA  1 
ATOM   971  C C   . GLN A 1 120 ? -24.986 -11.644 43.717  1   44.82  ? 290 GLN D C   1 
ATOM   972  O O   . GLN A 1 120 ? -25.124 -11.505 42.508  1   43.23  ? 290 GLN D O   1 
ATOM   973  C CB  . GLN A 1 120 ? -23.544 -13.477 44.678  1   48.7   ? 290 GLN D CB  1 
ATOM   974  C CG  . GLN A 1 120 ? -22.108 -13.949 44.904  1   51.11  ? 290 GLN D CG  1 
ATOM   975  C CD  . GLN A 1 120 ? -22.06  -15.364 45.426  1   54.91  ? 290 GLN D CD  1 
ATOM   976  O OE1 . GLN A 1 120 ? -22.653 -15.688 46.466  1   58.91  ? 290 GLN D OE1 1 
ATOM   977  N NE2 . GLN A 1 120 ? -21.381 -16.226 44.685  1   54.19  ? 290 GLN D NE2 1 
ATOM   978  N N   . VAL A 1 121 ? -25.974 -11.427 44.582  1   45.58  ? 291 VAL D N   1 
ATOM   979  C CA  . VAL A 1 121 ? -27.301 -11.127 44.075  1   45.63  ? 291 VAL D CA  1 
ATOM   980  C C   . VAL A 1 121 ? -27.242 -9.843  43.25   1   43.67  ? 291 VAL D C   1 
ATOM   981  O O   . VAL A 1 121 ? -27.772 -9.772  42.151  1   44.59  ? 291 VAL D O   1 
ATOM   982  C CB  . VAL A 1 121 ? -28.356 -11.053 45.196  1   46.69  ? 291 VAL D CB  1 
ATOM   983  C CG1 . VAL A 1 121 ? -29.679 -10.564 44.631  1   44.52  ? 291 VAL D CG1 1 
ATOM   984  C CG2 . VAL A 1 121 ? -28.523 -12.409 45.869  1   45.65  ? 291 VAL D CG2 1 
ATOM   985  N N   . LEU A 1 122 ? -26.576 -8.825  43.776  1   45.34  ? 292 LEU D N   1 
ATOM   986  C CA  . LEU A 1 122 ? -26.611 -7.518  43.145  1   48.3   ? 292 LEU D CA  1 
ATOM   987  C C   . LEU A 1 122 ? -25.86  -7.532  41.826  1   46.74  ? 292 LEU D C   1 
ATOM   988  O O   . LEU A 1 122 ? -26.29  -6.875  40.882  1   45.75  ? 292 LEU D O   1 
ATOM   989  C CB  . LEU A 1 122 ? -26.011 -6.491  44.102  1   48.45  ? 292 LEU D CB  1 
ATOM   990  C CG  . LEU A 1 122 ? -26.841 -6.224  45.365  1   51.71  ? 292 LEU D CG  1 
ATOM   991  C CD1 . LEU A 1 122 ? -26.036 -5.4    46.367  1   54.1   ? 292 LEU D CD1 1 
ATOM   992  C CD2 . LEU A 1 122 ? -28.16  -5.533  45.032  1   50.06  ? 292 LEU D CD2 1 
ATOM   993  N N   . ARG A 1 123 ? -24.735 -8.256  41.814  1   45.5   ? 293 ARG D N   1 
ATOM   994  C CA  . ARG A 1 123 ? -23.899 -8.39   40.636  1   45.25  ? 293 ARG D CA  1 
ATOM   995  C C   . ARG A 1 123 ? -24.671 -9.175  39.584  1   42.25  ? 293 ARG D C   1 
ATOM   996  O O   . ARG A 1 123 ? -24.625 -8.816  38.421  1   42.69  ? 293 ARG D O   1 
ATOM   997  C CB  . ARG A 1 123 ? -22.5   -8.944  40.945  1   48.17  ? 293 ARG D CB  1 
ATOM   998  C CG  . ARG A 1 123 ? -21.608 -7.977  41.713  1   51.04  ? 293 ARG D CG  1 
ATOM   999  C CD  . ARG A 1 123 ? -20.123 -8.288  41.609  1   67.14  ? 293 ARG D CD  1 
ATOM   1000 N NE  . ARG A 1 123 ? -19.672 -7.98   40.241  1   89.7   ? 293 ARG D NE  1 
ATOM   1001 C CZ  . ARG A 1 123 ? -18.93  -6.928  39.84   1   98.69  ? 293 ARG D CZ  1 
ATOM   1002 N NH1 . ARG A 1 123 ? -18.852 -6.644  38.549  1   95.91  ? 293 ARG D NH1 1 
ATOM   1003 N NH2 . ARG A 1 123 ? -18.335 -6.115  40.71   1   98.01  ? 293 ARG D NH2 1 
ATOM   1004 N N   . MET A 1 124 ? -25.403 -10.212 40.003  1   40.47  ? 294 MET D N   1 
ATOM   1005 C CA  . MET A 1 124 ? -26.192 -10.982 39.059  1   39.69  ? 294 MET D CA  1 
ATOM   1006 C C   . MET A 1 124 ? -27.301 -10.105 38.503  1   38.18  ? 294 MET D C   1 
ATOM   1007 O O   . MET A 1 124 ? -27.577 -10.135 37.302  1   39.68  ? 294 MET D O   1 
ATOM   1008 C CB  . MET A 1 124 ? -26.813 -12.228 39.683  1   38.74  ? 294 MET D CB  1 
ATOM   1009 C CG  . MET A 1 124 ? -27.563 -13.067 38.655  1   38.37  ? 294 MET D CG  1 
ATOM   1010 S SD  . MET A 1 124 ? -26.675 -13.821 37.275  1   42.2   ? 294 MET D SD  1 
ATOM   1011 C CE  . MET A 1 124 ? -25.862 -15.213 38.087  1   40.27  ? 294 MET D CE  1 
ATOM   1012 N N   . GLU A 1 125 ? -27.907 -9.3    39.375  1   37.23  ? 295 GLU D N   1 
ATOM   1013 C CA  . GLU A 1 125 ? -28.908 -8.345  38.922  1   37.9   ? 295 GLU D CA  1 
ATOM   1014 C C   . GLU A 1 125 ? -28.389 -7.54   37.729  1   40.24  ? 295 GLU D C   1 
ATOM   1015 O O   . GLU A 1 125 ? -29.058 -7.425  36.702  1   41.28  ? 295 GLU D O   1 
ATOM   1016 C CB  . GLU A 1 125 ? -29.341 -7.39   40.032  1   37.69  ? 295 GLU D CB  1 
ATOM   1017 C CG  . GLU A 1 125 ? -30.428 -6.438  39.557  1   37.44  ? 295 GLU D CG  1 
ATOM   1018 C CD  . GLU A 1 125 ? -30.859 -5.403  40.562  1   41.19  ? 295 GLU D CD  1 
ATOM   1019 O OE1 . GLU A 1 125 ? -29.991 -4.545  40.839  1   43.63  ? 295 GLU D OE1 1 
ATOM   1020 O OE2 . GLU A 1 125 ? -32.029 -5.426  41.022  1   38.13  ? 295 GLU D OE2 1 
ATOM   1021 N N   . HIS A 1 126 ? -27.186 -6.978  37.87   1   40.06  ? 296 HIS D N   1 
ATOM   1022 C CA  . HIS A 1 126 ? -26.654 -6.097  36.851  1   41.73  ? 296 HIS D CA  1 
ATOM   1023 C C   . HIS A 1 126 ? -26.351 -6.911  35.587  1   42.5   ? 296 HIS D C   1 
ATOM   1024 O O   . HIS A 1 126 ? -26.564 -6.438  34.47   1   43.77  ? 296 HIS D O   1 
ATOM   1025 C CB  . HIS A 1 126 ? -25.475 -5.283  37.416  1   45.02  ? 296 HIS D CB  1 
ATOM   1026 C CG  . HIS A 1 126 ? -25.085 -4.149  36.525  1   52.92  ? 296 HIS D CG  1 
ATOM   1027 N ND1 . HIS A 1 126 ? -24.043 -3.288  36.789  1   55.01  ? 296 HIS D ND1 1 
ATOM   1028 C CD2 . HIS A 1 126 ? -25.662 -3.687  35.379  1   53.08  ? 296 HIS D CD2 1 
ATOM   1029 C CE1 . HIS A 1 126 ? -23.969 -2.399  35.805  1   56.74  ? 296 HIS D CE1 1 
ATOM   1030 N NE2 . HIS A 1 126 ? -24.956 -2.602  34.955  1   55.85  ? 296 HIS D NE2 1 
ATOM   1031 N N   . LEU A 1 127 ? -25.853 -8.142  35.755  1   41.77  ? 297 LEU D N   1 
ATOM   1032 C CA  . LEU A 1 127 ? -25.488 -8.963  34.616  1   40.9   ? 297 LEU D CA  1 
ATOM   1033 C C   . LEU A 1 127 ? -26.744 -9.315  33.841  1   40.37  ? 297 LEU D C   1 
ATOM   1034 O O   . LEU A 1 127 ? -26.737 -9.254  32.615  1   42.46  ? 297 LEU D O   1 
ATOM   1035 C CB  . LEU A 1 127 ? -24.732 -10.228 35.021  1   41.15  ? 297 LEU D CB  1 
ATOM   1036 C CG  . LEU A 1 127 ? -24.384 -11.168 33.86   1   39.04  ? 297 LEU D CG  1 
ATOM   1037 C CD1 . LEU A 1 127 ? -23.322 -10.539 32.971  1   37.52  ? 297 LEU D CD1 1 
ATOM   1038 C CD2 . LEU A 1 127 ? -23.959 -12.51  34.386  1   38.22  ? 297 LEU D CD2 1 
ATOM   1039 N N   . VAL A 1 128 ? -27.809 -9.642  34.574  1   39.15  ? 298 VAL D N   1 
ATOM   1040 C CA  . VAL A 1 128 ? -29.079 -9.955  33.951  1   38.72  ? 298 VAL D CA  1 
ATOM   1041 C C   . VAL A 1 128 ? -29.592 -8.767  33.146  1   40.27  ? 298 VAL D C   1 
ATOM   1042 O O   . VAL A 1 128 ? -30.058 -8.952  32.015  1   42.14  ? 298 VAL D O   1 
ATOM   1043 C CB  . VAL A 1 128 ? -30.127 -10.489 34.935  1   39.51  ? 298 VAL D CB  1 
ATOM   1044 C CG1 . VAL A 1 128 ? -31.483 -10.633 34.247  1   39.19  ? 298 VAL D CG1 1 
ATOM   1045 C CG2 . VAL A 1 128 ? -29.718 -11.852 35.497  1   38.34  ? 298 VAL D CG2 1 
ATOM   1046 N N   . LEU A 1 129 ? -29.457 -7.557  33.71   1   41.46  ? 299 LEU D N   1 
ATOM   1047 C CA  . LEU A 1 129 ? -29.885 -6.343  33.03   1   40.87  ? 299 LEU D CA  1 
ATOM   1048 C C   . LEU A 1 129 ? -29.121 -6.179  31.723  1   44.88  ? 299 LEU D C   1 
ATOM   1049 O O   . LEU A 1 129 ? -29.727 -5.828  30.711  1   46.14  ? 299 LEU D O   1 
ATOM   1050 C CB  . LEU A 1 129 ? -29.789 -5.103  33.912  1   39.99  ? 299 LEU D CB  1 
ATOM   1051 C CG  . LEU A 1 129 ? -30.966 -4.893  34.88   1   42.47  ? 299 LEU D CG  1 
ATOM   1052 C CD1 . LEU A 1 129 ? -30.626 -3.825  35.908  1   40.02  ? 299 LEU D CD1 1 
ATOM   1053 C CD2 . LEU A 1 129 ? -32.285 -4.547  34.155  1   37.53  ? 299 LEU D CD2 1 
ATOM   1054 N N   . LYS A 1 130 ? -27.805 -6.467  31.751  1   45.56  ? 300 LYS D N   1 
ATOM   1055 C CA  . LYS A 1 130 ? -26.972 -6.277  30.574  1   44.94  ? 300 LYS D CA  1 
ATOM   1056 C C   . LYS A 1 130 ? -27.335 -7.283  29.486  1   43.83  ? 300 LYS D C   1 
ATOM   1057 O O   . LYS A 1 130 ? -27.346 -6.951  28.301  1   44.49  ? 300 LYS D O   1 
ATOM   1058 C CB  . LYS A 1 130 ? -25.477 -6.386  30.889  1   47.72  ? 300 LYS D CB  1 
ATOM   1059 C CG  . LYS A 1 130 ? -24.865 -5.257  31.69   1   47.96  ? 300 LYS D CG  1 
ATOM   1060 C CD  . LYS A 1 130 ? -23.396 -5.516  32.001  1   54.87  ? 300 LYS D CD  1 
ATOM   1061 C CE  . LYS A 1 130 ? -22.761 -4.426  32.805  1   67.81  ? 300 LYS D CE  1 
ATOM   1062 N NZ  . LYS A 1 130 ? -21.383 -4.696  33.232  1   77.64  ? 300 LYS D NZ  1 
ATOM   1063 N N   . VAL A 1 131 ? -27.62  -8.524  29.89   1   42.23  ? 301 VAL D N   1 
ATOM   1064 C CA  . VAL A 1 131 ? -27.898 -9.556  28.908  1   45.18  ? 301 VAL D CA  1 
ATOM   1065 C C   . VAL A 1 131 ? -29.246 -9.329  28.211  1   51.22  ? 301 VAL D C   1 
ATOM   1066 O O   . VAL A 1 131 ? -29.349 -9.535  27.007  1   50.21  ? 301 VAL D O   1 
ATOM   1067 C CB  . VAL A 1 131 ? -27.816 -10.926 29.581  1   43.68  ? 301 VAL D CB  1 
ATOM   1068 C CG1 . VAL A 1 131 ? -28.419 -11.997 28.689  1   40.84  ? 301 VAL D CG1 1 
ATOM   1069 C CG2 . VAL A 1 131 ? -26.376 -11.254 30.001  1   41.58  ? 301 VAL D CG2 1 
ATOM   1070 N N   . LEU A 1 132 ? -30.276 -8.89   28.955  1   52.43  ? 302 LEU D N   1 
ATOM   1071 C CA  . LEU A 1 132 ? -31.588 -8.598  28.376  1   46.56  ? 302 LEU D CA  1 
ATOM   1072 C C   . LEU A 1 132 ? -31.597 -7.193  27.78   1   46.94  ? 302 LEU D C   1 
ATOM   1073 O O   . LEU A 1 132 ? -32.622 -6.738  27.283  1   49.48  ? 302 LEU D O   1 
ATOM   1074 C CB  . LEU A 1 132 ? -32.652 -8.7    29.469  1   46.26  ? 302 LEU D CB  1 
ATOM   1075 C CG  . LEU A 1 132 ? -32.75  -10.046 30.195  1   50.03  ? 302 LEU D CG  1 
ATOM   1076 C CD1 . LEU A 1 132 ? -33.861 -10.1   31.218  1   50.4   ? 302 LEU D CD1 1 
ATOM   1077 C CD2 . LEU A 1 132 ? -32.993 -11.143 29.191  1   50.59  ? 302 LEU D CD2 1 
ATOM   1078 N N   . ALA A 1 133 ? -30.484 -6.467  27.93   1   44.88  ? 303 ALA D N   1 
ATOM   1079 C CA  . ALA A 1 133 ? -30.387 -5.072  27.51   1   45.44  ? 303 ALA D CA  1 
ATOM   1080 C C   . ALA A 1 133 ? -31.537 -4.204  28.052  1   45.62  ? 303 ALA D C   1 
ATOM   1081 O O   . ALA A 1 133 ? -32.032 -3.336  27.343  1   44.29  ? 303 ALA D O   1 
ATOM   1082 C CB  . ALA A 1 133 ? -30.287 -5.03   26.001  1   43.48  ? 303 ALA D CB  1 
ATOM   1083 N N   . PHE A 1 134 ? -31.967 -4.452  29.305  1   44.91  ? 304 PHE D N   1 
ATOM   1084 C CA  . PHE A 1 134 ? -33.027 -3.707  29.98   1   46.15  ? 304 PHE D CA  1 
ATOM   1085 C C   . PHE A 1 134 ? -34.391 -3.845  29.304  1   47.82  ? 304 PHE D C   1 
ATOM   1086 O O   . PHE A 1 134 ? -35.288 -3.079  29.635  1   47.04  ? 304 PHE D O   1 
ATOM   1087 C CB  . PHE A 1 134 ? -32.787 -2.192  30.052  1   48.87  ? 304 PHE D CB  1 
ATOM   1088 C CG  . PHE A 1 134 ? -31.859 -1.762  31.178  1   51.86  ? 304 PHE D CG  1 
ATOM   1089 C CD1 . PHE A 1 134 ? -30.483 -1.859  31.043  1   50.26  ? 304 PHE D CD1 1 
ATOM   1090 C CD2 . PHE A 1 134 ? -32.38  -1.301  32.386  1   52.65  ? 304 PHE D CD2 1 
ATOM   1091 C CE1 . PHE A 1 134 ? -29.657 -1.492  32.087  1   53.49  ? 304 PHE D CE1 1 
ATOM   1092 C CE2 . PHE A 1 134 ? -31.545 -0.923  33.421  1   52.97  ? 304 PHE D CE2 1 
ATOM   1093 C CZ  . PHE A 1 134 ? -30.191 -1.012  33.268  1   55     ? 304 PHE D CZ  1 
ATOM   1094 N N   A ASP A 1 135 ? -34.525 -4.764  28.336  0.5 47.65  ? 305 ASP D N   1 
ATOM   1095 N N   B ASP A 1 135 ? -34.525 -4.794  28.366  0.5 49.66  ? 305 ASP D N   1 
ATOM   1096 C CA  A ASP A 1 135 ? -35.808 -5.006  27.698  0.5 46.55  ? 305 ASP D CA  1 
ATOM   1097 C CA  B ASP A 1 135 ? -35.793 -5.064  27.709  0.5 49.99  ? 305 ASP D CA  1 
ATOM   1098 C C   A ASP A 1 135 ? -36.628 -5.879  28.643  0.5 46.23  ? 305 ASP D C   1 
ATOM   1099 C C   B ASP A 1 135 ? -36.633 -5.905  28.66   0.5 48.25  ? 305 ASP D C   1 
ATOM   1100 O O   A ASP A 1 135 ? -36.704 -7.09   28.445  0.5 49.13  ? 305 ASP D O   1 
ATOM   1101 O O   B ASP A 1 135 ? -36.731 -7.12   28.483  0.5 51.22  ? 305 ASP D O   1 
ATOM   1102 C CB  A ASP A 1 135 ? -35.646 -5.542  26.278  0.5 47.45  ? 305 ASP D CB  1 
ATOM   1103 C CB  B ASP A 1 135 ? -35.579 -5.743  26.366  0.5 54.8   ? 305 ASP D CB  1 
ATOM   1104 C CG  A ASP A 1 135 ? -34.85  -4.666  25.308  0.5 48.47  ? 305 ASP D CG  1 
ATOM   1105 C CG  B ASP A 1 135 ? -36.799 -5.818  25.465  0.5 60.39  ? 305 ASP D CG  1 
ATOM   1106 O OD1 A ASP A 1 135 ? -35.097 -3.444  25.263  0.5 48.43  ? 305 ASP D OD1 1 
ATOM   1107 O OD1 B ASP A 1 135 ? -37.786 -5.119  25.778  0.5 62.98  ? 305 ASP D OD1 1 
ATOM   1108 O OD2 A ASP A 1 135 ? -33.987 -5.206  24.583  0.5 49.79  ? 305 ASP D OD2 1 
ATOM   1109 O OD2 B ASP A 1 135 ? -36.738 -6.526  24.436  0.5 65.01  ? 305 ASP D OD2 1 
ATOM   1110 N N   . LEU A 1 136 ? -37.223 -5.247  29.673  1   44.69  ? 306 LEU D N   1 
ATOM   1111 C CA  . LEU A 1 136 ? -37.911 -5.94   30.757  1   42.35  ? 306 LEU D CA  1 
ATOM   1112 C C   . LEU A 1 136 ? -39.444 -5.945  30.601  1   44.86  ? 306 LEU D C   1 
ATOM   1113 O O   . LEU A 1 136 ? -40.105 -6.717  31.311  1   46.75  ? 306 LEU D O   1 
ATOM   1114 C CB  . LEU A 1 136 ? -37.502 -5.347  32.105  1   43.73  ? 306 LEU D CB  1 
ATOM   1115 C CG  . LEU A 1 136 ? -36.058 -5.546  32.597  1   47.17  ? 306 LEU D CG  1 
ATOM   1116 C CD1 . LEU A 1 136 ? -36.094 -5.685  34.105  1   47.39  ? 306 LEU D CD1 1 
ATOM   1117 C CD2 . LEU A 1 136 ? -35.286 -6.728  32.028  1   45.58  ? 306 LEU D CD2 1 
ATOM   1118 N N   . ALA A 1 137 ? -40.022 -5.076  29.742  1   40.33  ? 307 ALA D N   1 
ATOM   1119 C CA  . ALA A 1 137 ? -41.481 -4.969  29.669  1   41.5   ? 307 ALA D CA  1 
ATOM   1120 C C   . ALA A 1 137 ? -42.056 -6.078  28.795  1   42.1   ? 307 ALA D C   1 
ATOM   1121 O O   . ALA A 1 137 ? -42.554 -5.795  27.706  1   42.67  ? 307 ALA D O   1 
ATOM   1122 C CB  . ALA A 1 137 ? -41.914 -3.615  29.166  1   39.3   ? 307 ALA D CB  1 
ATOM   1123 N N   . ALA A 1 138 ? -42     -7.332  29.268  1   41.44  ? 308 ALA D N   1 
ATOM   1124 C CA  . ALA A 1 138 ? -42.307 -8.467  28.408  1   42.79  ? 308 ALA D CA  1 
ATOM   1125 C C   . ALA A 1 138 ? -43.77  -8.825  28.558  1   48.66  ? 308 ALA D C   1 
ATOM   1126 O O   . ALA A 1 138 ? -44.288 -8.856  29.672  1   53.42  ? 308 ALA D O   1 
ATOM   1127 C CB  . ALA A 1 138 ? -41.476 -9.684  28.75   1   39.67  ? 308 ALA D CB  1 
ATOM   1128 N N   . PRO A 1 139 ? -44.464 -9.133  27.446  1   51.34  ? 309 PRO D N   1 
ATOM   1129 C CA  . PRO A 1 139 ? -45.85  -9.587  27.538  1   51.39  ? 309 PRO D CA  1 
ATOM   1130 C C   . PRO A 1 139 ? -45.844 -10.96  28.2    1   51.15  ? 309 PRO D C   1 
ATOM   1131 O O   . PRO A 1 139 ? -44.967 -11.781 27.942  1   54.19  ? 309 PRO D O   1 
ATOM   1132 C CB  . PRO A 1 139 ? -46.299 -9.608  26.067  1   51.68  ? 309 PRO D CB  1 
ATOM   1133 C CG  . PRO A 1 139 ? -45.29  -8.745  25.323  1   50.75  ? 309 PRO D CG  1 
ATOM   1134 C CD  . PRO A 1 139 ? -43.979 -9.037  26.052  1   51.52  ? 309 PRO D CD  1 
ATOM   1135 N N   . THR A 1 140 ? -46.808 -11.159 29.097  1   49.33  ? 310 THR D N   1 
ATOM   1136 C CA  . THR A 1 140 ? -46.954 -12.366 29.894  1   48.4   ? 310 THR D CA  1 
ATOM   1137 C C   . THR A 1 140 ? -48.28  -13.027 29.499  1   52.52  ? 310 THR D C   1 
ATOM   1138 O O   . THR A 1 140 ? -49.175 -12.372 28.95   1   50     ? 310 THR D O   1 
ATOM   1139 C CB  . THR A 1 140 ? -46.966 -12.035 31.393  1   45.97  ? 310 THR D CB  1 
ATOM   1140 O OG1 . THR A 1 140 ? -48.109 -11.238 31.676  1   47.77  ? 310 THR D OG1 1 
ATOM   1141 C CG2 . THR A 1 140 ? -45.741 -11.277 31.881  1   44.33  ? 310 THR D CG2 1 
ATOM   1142 N N   . ILE A 1 141 ? -48.408 -14.311 29.847  1   51.35  ? 311 ILE D N   1 
ATOM   1143 C CA  . ILE A 1 141 ? -49.662 -15.024 29.704  1   57.11  ? 311 ILE D CA  1 
ATOM   1144 C C   . ILE A 1 141 ? -50.791 -14.221 30.352  1   60.08  ? 311 ILE D C   1 
ATOM   1145 O O   . ILE A 1 141 ? -51.89  -14.141 29.791  1   61.1   ? 311 ILE D O   1 
ATOM   1146 C CB  . ILE A 1 141 ? -49.556 -16.442 30.292  1   53.92  ? 311 ILE D CB  1 
ATOM   1147 C CG1 . ILE A 1 141 ? -48.539 -17.294 29.517  1   51.07  ? 311 ILE D CG1 1 
ATOM   1148 C CG2 . ILE A 1 141 ? -50.937 -17.085 30.357  1   51.86  ? 311 ILE D CG2 1 
ATOM   1149 C CD1 . ILE A 1 141 ? -48.109 -18.556 30.25   1   49.17  ? 311 ILE D CD1 1 
ATOM   1150 N N   . ASN A 1 142 ? -50.503 -13.605 31.511  1   57.15  ? 312 ASN D N   1 
ATOM   1151 C CA  . ASN A 1 142 ? -51.534 -12.91  32.264  1   56.36  ? 312 ASN D CA  1 
ATOM   1152 C C   . ASN A 1 142 ? -52.029 -11.686 31.506  1   56.02  ? 312 ASN D C   1 
ATOM   1153 O O   . ASN A 1 142 ? -53.228 -11.407 31.501  1   59.21  ? 312 ASN D O   1 
ATOM   1154 C CB  . ASN A 1 142 ? -51.079 -12.565 33.674  1   56.72  ? 312 ASN D CB  1 
ATOM   1155 C CG  . ASN A 1 142 ? -51.17  -13.763 34.581  1   60.97  ? 312 ASN D CG  1 
ATOM   1156 O OD1 . ASN A 1 142 ? -51.115 -14.906 34.11   1   69.25  ? 312 ASN D OD1 1 
ATOM   1157 N ND2 . ASN A 1 142 ? -51.288 -13.529 35.88   1   64.22  ? 312 ASN D ND2 1 
ATOM   1158 N N   . GLN A 1 143 ? -51.106 -10.943 30.89   1   54.84  ? 313 GLN D N   1 
ATOM   1159 C CA  . GLN A 1 143 ? -51.502 -9.76   30.137  1   54.44  ? 313 GLN D CA  1 
ATOM   1160 C C   . GLN A 1 143 ? -52.483 -10.122 29.028  1   54.84  ? 313 GLN D C   1 
ATOM   1161 O O   . GLN A 1 143 ? -53.295 -9.289  28.651  1   59.62  ? 313 GLN D O   1 
ATOM   1162 C CB  . GLN A 1 143 ? -50.313 -9.029  29.527  1   50.75  ? 313 GLN D CB  1 
ATOM   1163 C CG  . GLN A 1 143 ? -49.595 -8.203  30.577  1   48.41  ? 313 GLN D CG  1 
ATOM   1164 C CD  . GLN A 1 143 ? -48.304 -7.608  30.066  1   49.51  ? 313 GLN D CD  1 
ATOM   1165 O OE1 . GLN A 1 143 ? -48.305 -6.797  29.132  1   47.61  ? 313 GLN D OE1 1 
ATOM   1166 N NE2 . GLN A 1 143 ? -47.203 -7.996  30.704  1   45.45  ? 313 GLN D NE2 1 
ATOM   1167 N N   . PHE A 1 144 ? -52.376 -11.339 28.483  1   52.36  ? 314 PHE D N   1 
ATOM   1168 C CA  . PHE A 1 144 ? -53.306 -11.746 27.449  1   53.66  ? 314 PHE D CA  1 
ATOM   1169 C C   . PHE A 1 144 ? -54.597 -12.243 28.097  1   55.72  ? 314 PHE D C   1 
ATOM   1170 O O   . PHE A 1 144 ? -55.681 -11.878 27.649  1   56.58  ? 314 PHE D O   1 
ATOM   1171 C CB  . PHE A 1 144 ? -52.672 -12.721 26.471  1   53.06  ? 314 PHE D CB  1 
ATOM   1172 C CG  . PHE A 1 144 ? -51.688 -12.066 25.527  1   54.36  ? 314 PHE D CG  1 
ATOM   1173 C CD1 . PHE A 1 144 ? -52.141 -11.286 24.468  1   56.42  ? 314 PHE D CD1 1 
ATOM   1174 C CD2 . PHE A 1 144 ? -50.317 -12.25  25.687  1   51.36  ? 314 PHE D CD2 1 
ATOM   1175 C CE1 . PHE A 1 144 ? -51.232 -10.695 23.594  1   54.76  ? 314 PHE D CE1 1 
ATOM   1176 C CE2 . PHE A 1 144 ? -49.421 -11.666 24.808  1   50.9   ? 314 PHE D CE2 1 
ATOM   1177 C CZ  . PHE A 1 144 ? -49.879 -10.89  23.764  1   51.53  ? 314 PHE D CZ  1 
ATOM   1178 N N   . LEU A 1 145 ? -54.466 -13.025 29.175  1   55.62  ? 315 LEU D N   1 
ATOM   1179 C CA  . LEU A 1 145 ? -55.61  -13.532 29.923  1   58.45  ? 315 LEU D CA  1 
ATOM   1180 C C   . LEU A 1 145 ? -56.578 -12.422 30.34   1   60.17  ? 315 LEU D C   1 
ATOM   1181 O O   . LEU A 1 145 ? -57.765 -12.496 30.012  1   65.21  ? 315 LEU D O   1 
ATOM   1182 C CB  . LEU A 1 145 ? -55.171 -14.34  31.139  1   56.49  ? 315 LEU D CB  1 
ATOM   1183 C CG  . LEU A 1 145 ? -54.699 -15.767 30.878  1   53.62  ? 315 LEU D CG  1 
ATOM   1184 C CD1 . LEU A 1 145 ? -54.576 -16.433 32.237  1   53.28  ? 315 LEU D CD1 1 
ATOM   1185 C CD2 . LEU A 1 145 ? -55.661 -16.52  29.994  1   55.01  ? 315 LEU D CD2 1 
ATOM   1186 N N   . THR A 1 146 ? -56.082 -11.398 31.048  1   56.83  ? 316 THR D N   1 
ATOM   1187 C CA  . THR A 1 146 ? -56.93  -10.32  31.542  1   58.61  ? 316 THR D CA  1 
ATOM   1188 C C   . THR A 1 146 ? -57.733 -9.684  30.407  1   62.25  ? 316 THR D C   1 
ATOM   1189 O O   . THR A 1 146 ? -58.851 -9.235  30.653  1   72.23  ? 316 THR D O   1 
ATOM   1190 C CB  . THR A 1 146 ? -56.153 -9.259  32.327  1   60.44  ? 316 THR D CB  1 
ATOM   1191 O OG1 . THR A 1 146 ? -55.206 -8.666  31.432  1   59.35  ? 316 THR D OG1 1 
ATOM   1192 C CG2 . THR A 1 146 ? -55.514 -9.805  33.596  1   57.19  ? 316 THR D CG2 1 
ATOM   1193 N N   . GLN A 1 147 ? -57.183 -9.641  29.18   1   60.62  ? 317 GLN D N   1 
ATOM   1194 C CA  . GLN A 1 147 ? -57.84  -8.989  28.05   1   62.63  ? 317 GLN D CA  1 
ATOM   1195 C C   . GLN A 1 147 ? -58.939 -9.88   27.468  1   68.02  ? 317 GLN D C   1 
ATOM   1196 O O   . GLN A 1 147 ? -59.953 -9.387  26.926  1   66.09  ? 317 GLN D O   1 
ATOM   1197 C CB  . GLN A 1 147 ? -56.889 -8.69   26.892  1   63.56  ? 317 GLN D CB  1 
ATOM   1198 C CG  . GLN A 1 147 ? -55.893 -7.562  27.155  1   64.24  ? 317 GLN D CG  1 
ATOM   1199 C CD  . GLN A 1 147 ? -55.118 -7.159  25.916  1   72.24  ? 317 GLN D CD  1 
ATOM   1200 O OE1 . GLN A 1 147 ? -53.891 -7.294  25.873  1   83.88  ? 317 GLN D OE1 1 
ATOM   1201 N NE2 . GLN A 1 147 ? -55.803 -6.677  24.883  1   73.02  ? 317 GLN D NE2 1 
ATOM   1202 N N   . TYR A 1 148 ? -58.683 -11.198 27.54   1   68.52  ? 318 TYR D N   1 
ATOM   1203 C CA  . TYR A 1 148 ? -59.592 -12.214 27.03   1   67.86  ? 318 TYR D CA  1 
ATOM   1204 C C   . TYR A 1 148 ? -60.802 -12.309 27.957  1   68.63  ? 318 TYR D C   1 
ATOM   1205 O O   . TYR A 1 148 ? -61.904 -12.577 27.485  1   71.57  ? 318 TYR D O   1 
ATOM   1206 C CB  . TYR A 1 148 ? -58.913 -13.584 26.929  1   64.04  ? 318 TYR D CB  1 
ATOM   1207 C CG  . TYR A 1 148 ? -57.746 -13.746 25.969  1   61.21  ? 318 TYR D CG  1 
ATOM   1208 C CD1 . TYR A 1 148 ? -57.499 -12.827 24.948  1   59.71  ? 318 TYR D CD1 1 
ATOM   1209 C CD2 . TYR A 1 148 ? -56.904 -14.844 26.084  1   59.12  ? 318 TYR D CD2 1 
ATOM   1210 C CE1 . TYR A 1 148 ? -56.438 -12.991 24.072  1   58.98  ? 318 TYR D CE1 1 
ATOM   1211 C CE2 . TYR A 1 148 ? -55.851 -15.026 25.206  1   59.47  ? 318 TYR D CE2 1 
ATOM   1212 C CZ  . TYR A 1 148 ? -55.606 -14.097 24.203  1   60.58  ? 318 TYR D CZ  1 
ATOM   1213 O OH  . TYR A 1 148 ? -54.536 -14.295 23.355  1   61.22  ? 318 TYR D OH  1 
ATOM   1214 N N   . PHE A 1 149 ? -60.582 -12.096 29.267  1   66.75  ? 319 PHE D N   1 
ATOM   1215 C CA  . PHE A 1 149 ? -61.659 -12.107 30.238  1   69.26  ? 319 PHE D CA  1 
ATOM   1216 C C   . PHE A 1 149 ? -62.758 -11.121 29.837  1   72.52  ? 319 PHE D C   1 
ATOM   1217 O O   . PHE A 1 149 ? -63.95  -11.434 29.958  1   72.89  ? 319 PHE D O   1 
ATOM   1218 C CB  . PHE A 1 149 ? -61.143 -11.84  31.643  1   66.48  ? 319 PHE D CB  1 
ATOM   1219 C CG  . PHE A 1 149 ? -60.274 -12.941 32.222  1   68.99  ? 319 PHE D CG  1 
ATOM   1220 C CD1 . PHE A 1 149 ? -60.26  -14.221 31.663  1   66.89  ? 319 PHE D CD1 1 
ATOM   1221 C CD2 . PHE A 1 149 ? -59.467 -12.679 33.337  1   67.65  ? 319 PHE D CD2 1 
ATOM   1222 C CE1 . PHE A 1 149 ? -59.462 -15.215 32.219  1   67.6   ? 319 PHE D CE1 1 
ATOM   1223 C CE2 . PHE A 1 149 ? -58.666 -13.671 33.885  1   66.8   ? 319 PHE D CE2 1 
ATOM   1224 C CZ  . PHE A 1 149 ? -58.654 -14.936 33.317  1   69.43  ? 319 PHE D CZ  1 
ATOM   1225 N N   . LEU A 1 150 ? -62.344 -9.95   29.342  1   71.72  ? 320 LEU D N   1 
ATOM   1226 C CA  . LEU A 1 150 ? -63.266 -8.885  28.96   1   77.4   ? 320 LEU D CA  1 
ATOM   1227 C C   . LEU A 1 150 ? -64.356 -9.399  28.015  1   77.91  ? 320 LEU D C   1 
ATOM   1228 O O   . LEU A 1 150 ? -65.439 -8.825  27.965  1   79.04  ? 320 LEU D O   1 
ATOM   1229 C CB  . LEU A 1 150 ? -62.509 -7.69   28.368  1   75.96  ? 320 LEU D CB  1 
ATOM   1230 C CG  . LEU A 1 150 ? -61.572 -6.927  29.315  1   73.03  ? 320 LEU D CG  1 
ATOM   1231 C CD1 . LEU A 1 150 ? -60.8   -5.837  28.574  1   68.2   ? 320 LEU D CD1 1 
ATOM   1232 C CD2 . LEU A 1 150 ? -62.314 -6.327  30.514  1   72.49  ? 320 LEU D CD2 1 
ATOM   1233 N N   . HIS A 1 151 ? -64.058 -10.472 27.268  1   78.71  ? 321 HIS D N   1 
ATOM   1234 C CA  . HIS A 1 151 ? -64.97  -10.997 26.267  1   81.33  ? 321 HIS D CA  1 
ATOM   1235 C C   . HIS A 1 151 ? -66.052 -11.889 26.879  1   86.37  ? 321 HIS D C   1 
ATOM   1236 O O   . HIS A 1 151 ? -67.028 -12.223 26.191  1   90.14  ? 321 HIS D O   1 
ATOM   1237 C CB  . HIS A 1 151 ? -64.179 -11.648 25.135  1   81.24  ? 321 HIS D CB  1 
ATOM   1238 C CG  . HIS A 1 151 ? -63.573 -10.662 24.197  1   83.05  ? 321 HIS D CG  1 
ATOM   1239 N ND1 . HIS A 1 151 ? -63.906 -10.599 22.855  1   86.42  ? 321 HIS D ND1 1 
ATOM   1240 C CD2 . HIS A 1 151 ? -62.64  -9.718  24.406  1   77.65  ? 321 HIS D CD2 1 
ATOM   1241 C CE1 . HIS A 1 151 ? -63.194 -9.639  22.275  1   85.39  ? 321 HIS D CE1 1 
ATOM   1242 N NE2 . HIS A 1 151 ? -62.419 -9.089  23.202  1   80.45  ? 321 HIS D NE2 1 
ATOM   1243 N N   . GLN A 1 152 ? -65.891 -12.246 28.165  1   86.52  ? 322 GLN D N   1 
ATOM   1244 C CA  . GLN A 1 152 ? -66.925 -12.967 28.894  1   92.63  ? 322 GLN D CA  1 
ATOM   1245 C C   . GLN A 1 152 ? -68.153 -12.082 29.105  1   100.86 ? 322 GLN D C   1 
ATOM   1246 O O   . GLN A 1 152 ? -68.045 -10.855 29.106  1   100.49 ? 322 GLN D O   1 
ATOM   1247 C CB  . GLN A 1 152 ? -66.486 -13.308 30.307  1   86.64  ? 322 GLN D CB  1 
ATOM   1248 C CG  . GLN A 1 152 ? -65.407 -14.372 30.388  1   84.12  ? 322 GLN D CG  1 
ATOM   1249 C CD  . GLN A 1 152 ? -65.047 -14.576 31.836  1   85.71  ? 322 GLN D CD  1 
ATOM   1250 O OE1 . GLN A 1 152 ? -65.587 -15.468 32.505  1   87.81  ? 322 GLN D OE1 1 
ATOM   1251 N NE2 . GLN A 1 152 ? -64.221 -13.667 32.347  1   79.08  ? 322 GLN D NE2 1 
ATOM   1252 N N   . GLN A 1 153 ? -69.303 -12.738 29.332  1   105.22 ? 323 GLN D N   1 
ATOM   1253 C CA  . GLN A 1 153 ? -70.592 -12.087 29.542  1   111.07 ? 323 GLN D CA  1 
ATOM   1254 C C   . GLN A 1 153 ? -71.547 -13.079 30.214  1   108.43 ? 323 GLN D C   1 
ATOM   1255 O O   . GLN A 1 153 ? -72.18  -13.889 29.535  1   106.46 ? 323 GLN D O   1 
ATOM   1256 C CB  . GLN A 1 153 ? -71.126 -11.463 28.245  1   117.44 ? 323 GLN D CB  1 
ATOM   1257 C CG  . GLN A 1 153 ? -70.889 -12.305 26.989  1   122.82 ? 323 GLN D CG  1 
ATOM   1258 C CD  . GLN A 1 153 ? -71.333 -11.656 25.691  1   124.94 ? 323 GLN D CD  1 
ATOM   1259 O OE1 . GLN A 1 153 ? -71.3   -12.276 24.622  1   122.36 ? 323 GLN D OE1 1 
ATOM   1260 N NE2 . GLN A 1 153 ? -71.766 -10.405 25.766  1   124.72 ? 323 GLN D NE2 1 
ATOM   1261 N N   . PRO A 1 154 ? -71.658 -13.093 31.571  1   107.45 ? 324 PRO D N   1 
ATOM   1262 C CA  . PRO A 1 154 ? -71.013 -12.106 32.449  1   104.65 ? 324 PRO D CA  1 
ATOM   1263 C C   . PRO A 1 154 ? -69.623 -12.621 32.816  1   102.35 ? 324 PRO D C   1 
ATOM   1264 O O   . PRO A 1 154 ? -69.216 -13.674 32.322  1   98.75  ? 324 PRO D O   1 
ATOM   1265 C CB  . PRO A 1 154 ? -71.955 -12.16  33.664  1   104.43 ? 324 PRO D CB  1 
ATOM   1266 C CG  . PRO A 1 154 ? -72.333 -13.629 33.774  1   104.85 ? 324 PRO D CG  1 
ATOM   1267 C CD  . PRO A 1 154 ? -72.34  -14.151 32.341  1   107.26 ? 324 PRO D CD  1 
ATOM   1268 N N   . ALA A 1 155 ? -68.931 -11.891 33.709  1   102.08 ? 325 ALA D N   1 
ATOM   1269 C CA  . ALA A 1 155 ? -67.678 -12.327 34.31   1   95.68  ? 325 ALA D CA  1 
ATOM   1270 C C   . ALA A 1 155 ? -67.941 -13.547 35.198  1   98.41  ? 325 ALA D C   1 
ATOM   1271 O O   . ALA A 1 155 ? -68.946 -13.582 35.906  1   99.91  ? 325 ALA D O   1 
ATOM   1272 C CB  . ALA A 1 155 ? -67.084 -11.186 35.105  1   85.5   ? 325 ALA D CB  1 
ATOM   1273 N N   . ASN A 1 156 ? -67.05  -14.552 35.126  1   96.54  ? 326 ASN D N   1 
ATOM   1274 C CA  . ASN A 1 156 ? -67.072 -15.705 36.014  1   95.52  ? 326 ASN D CA  1 
ATOM   1275 C C   . ASN A 1 156 ? -65.691 -15.885 36.634  1   94.97  ? 326 ASN D C   1 
ATOM   1276 O O   . ASN A 1 156 ? -64.712 -16.123 35.925  1   88.12  ? 326 ASN D O   1 
ATOM   1277 C CB  . ASN A 1 156 ? -67.453 -16.989 35.285  1   103.82 ? 326 ASN D CB  1 
ATOM   1278 C CG  . ASN A 1 156 ? -67.285 -18.222 36.149  1   109.41 ? 326 ASN D CG  1 
ATOM   1279 O OD1 . ASN A 1 156 ? -66.68  -19.212 35.721  1   110.25 ? 326 ASN D OD1 1 
ATOM   1280 N ND2 . ASN A 1 156 ? -67.823 -18.194 37.362  1   110.51 ? 326 ASN D ND2 1 
ATOM   1281 N N   . CYS A 1 157 ? -65.65  -15.799 37.97   1   99.57  ? 327 CYS D N   1 
ATOM   1282 C CA  . CYS A 1 157 ? -64.434 -15.825 38.772  1   94.5   ? 327 CYS D CA  1 
ATOM   1283 C C   . CYS A 1 157 ? -63.784 -17.211 38.764  1   89.41  ? 327 CYS D C   1 
ATOM   1284 O O   . CYS A 1 157 ? -62.588 -17.317 39.01   1   84.09  ? 327 CYS D O   1 
ATOM   1285 C CB  . CYS A 1 157 ? -64.731 -15.418 40.212  1   98.76  ? 327 CYS D CB  1 
ATOM   1286 S SG  . CYS A 1 157 ? -65.951 -16.51  40.995  1   127.36 ? 327 CYS D SG  1 
ATOM   1287 N N   . LYS A 1 158 ? -64.577 -18.267 38.532  1   91.27  ? 328 LYS D N   1 
ATOM   1288 C CA  . LYS A 1 158 ? -64.081 -19.637 38.511  1   91.94  ? 328 LYS D CA  1 
ATOM   1289 C C   . LYS A 1 158 ? -63.297 -19.879 37.22   1   87.25  ? 328 LYS D C   1 
ATOM   1290 O O   . LYS A 1 158 ? -62.225 -20.484 37.246  1   86.76  ? 328 LYS D O   1 
ATOM   1291 C CB  . LYS A 1 158 ? -65.238 -20.636 38.644  1   98.01  ? 328 LYS D CB  1 
ATOM   1292 C CG  . LYS A 1 158 ? -66.02  -20.576 39.957  1   107.02 ? 328 LYS D CG  1 
ATOM   1293 C CD  . LYS A 1 158 ? -65.322 -21.19  41.168  1   109.57 ? 328 LYS D CD  1 
ATOM   1294 C CE  . LYS A 1 158 ? -65.5   -22.682 41.307  1   108.46 ? 328 LYS D CE  1 
ATOM   1295 N NZ  . LYS A 1 158 ? -66.878 -23.101 41.586  1   105.89 ? 328 LYS D NZ  1 
ATOM   1296 N N   . VAL A 1 159 ? -63.854 -19.412 36.097  1   85.1   ? 329 VAL D N   1 
ATOM   1297 C CA  . VAL A 1 159 ? -63.198 -19.436 34.799  1   81.37  ? 329 VAL D CA  1 
ATOM   1298 C C   . VAL A 1 159 ? -61.921 -18.584 34.853  1   79.83  ? 329 VAL D C   1 
ATOM   1299 O O   . VAL A 1 159 ? -60.935 -18.92  34.206  1   78.11  ? 329 VAL D O   1 
ATOM   1300 C CB  . VAL A 1 159 ? -64.175 -19.007 33.678  1   80.02  ? 329 VAL D CB  1 
ATOM   1301 C CG1 . VAL A 1 159 ? -63.467 -18.494 32.434  1   74.11  ? 329 VAL D CG1 1 
ATOM   1302 C CG2 . VAL A 1 159 ? -65.142 -20.124 33.292  1   83.7   ? 329 VAL D CG2 1 
ATOM   1303 N N   . GLU A 1 160 ? -61.926 -17.498 35.642  1   78.51  ? 330 GLU D N   1 
ATOM   1304 C CA  . GLU A 1 160 ? -60.81  -16.563 35.697  1   76.02  ? 330 GLU D CA  1 
ATOM   1305 C C   . GLU A 1 160 ? -59.658 -17.135 36.516  1   73.15  ? 330 GLU D C   1 
ATOM   1306 O O   . GLU A 1 160 ? -58.503 -17.059 36.083  1   69.69  ? 330 GLU D O   1 
ATOM   1307 C CB  . GLU A 1 160 ? -61.223 -15.17  36.163  1   76.79  ? 330 GLU D CB  1 
ATOM   1308 C CG  . GLU A 1 160 ? -61.908 -14.384 35.051  1   80.82  ? 330 GLU D CG  1 
ATOM   1309 C CD  . GLU A 1 160 ? -62.341 -12.969 35.365  1   83.96  ? 330 GLU D CD  1 
ATOM   1310 O OE1 . GLU A 1 160 ? -62.155 -12.544 36.521  1   84.56  ? 330 GLU D OE1 1 
ATOM   1311 O OE2 . GLU A 1 160 ? -62.874 -12.311 34.444  1   83.47  ? 330 GLU D OE2 1 
ATOM   1312 N N   . SER A 1 161 ? -59.982 -17.718 37.677  1   72.92  ? 331 SER D N   1 
ATOM   1313 C CA  . SER A 1 161 ? -58.975 -18.411 38.468  1   73     ? 331 SER D CA  1 
ATOM   1314 C C   . SER A 1 161 ? -58.413 -19.595 37.688  1   73.42  ? 331 SER D C   1 
ATOM   1315 O O   . SER A 1 161 ? -57.199 -19.74  37.565  1   72.5   ? 331 SER D O   1 
ATOM   1316 C CB  . SER A 1 161 ? -59.506 -18.862 39.794  1   74.58  ? 331 SER D CB  1 
ATOM   1317 O OG  . SER A 1 161 ? -59.499 -17.793 40.728  1   74.89  ? 331 SER D OG  1 
ATOM   1318 N N   . LEU A 1 162 ? -59.311 -20.431 37.164  1   74.16  ? 332 LEU D N   1 
ATOM   1319 C CA  . LEU A 1 162 ? -58.894 -21.673 36.542  1   73.89  ? 332 LEU D CA  1 
ATOM   1320 C C   . LEU A 1 162 ? -57.909 -21.407 35.405  1   70.58  ? 332 LEU D C   1 
ATOM   1321 O O   . LEU A 1 162 ? -56.968 -22.181 35.231  1   72.62  ? 332 LEU D O   1 
ATOM   1322 C CB  . LEU A 1 162 ? -60.1   -22.478 36.062  1   74.69  ? 332 LEU D CB  1 
ATOM   1323 C CG  . LEU A 1 162 ? -59.759 -23.798 35.363  1   75.93  ? 332 LEU D CG  1 
ATOM   1324 C CD1 . LEU A 1 162 ? -58.774 -24.569 36.222  1   75.11  ? 332 LEU D CD1 1 
ATOM   1325 C CD2 . LEU A 1 162 ? -60.984 -24.667 35.076  1   79.15  ? 332 LEU D CD2 1 
ATOM   1326 N N   . ALA A 1 163 ? -58.149 -20.355 34.616  1   66.41  ? 333 ALA D N   1 
ATOM   1327 C CA  . ALA A 1 163 ? -57.284 -20.044 33.494  1   66.62  ? 333 ALA D CA  1 
ATOM   1328 C C   . ALA A 1 163 ? -55.929 -19.552 34.006  1   66.93  ? 333 ALA D C   1 
ATOM   1329 O O   . ALA A 1 163 ? -54.882 -19.976 33.508  1   68.66  ? 333 ALA D O   1 
ATOM   1330 C CB  . ALA A 1 163 ? -57.945 -19.051 32.561  1   65.89  ? 333 ALA D CB  1 
ATOM   1331 N N   . MET A 1 164 ? -55.96  -18.666 35.011  1   66.99  ? 334 MET D N   1 
ATOM   1332 C CA  . MET A 1 164 ? -54.754 -18.258 35.714  1   66.83  ? 334 MET D CA  1 
ATOM   1333 C C   . MET A 1 164 ? -53.969 -19.502 36.133  1   65.29  ? 334 MET D C   1 
ATOM   1334 O O   . MET A 1 164 ? -52.752 -19.541 35.93   1   63.28  ? 334 MET D O   1 
ATOM   1335 C CB  . MET A 1 164 ? -55.05  -17.388 36.95   1   69.34  ? 334 MET D CB  1 
ATOM   1336 C CG  . MET A 1 164 ? -55.432 -15.93  36.683  1   74.91  ? 334 MET D CG  1 
ATOM   1337 S SD  . MET A 1 164 ? -54.33  -14.972 35.608  1   76.17  ? 334 MET D SD  1 
ATOM   1338 C CE  . MET A 1 164 ? -54.346 -13.383 36.462  1   85.13  ? 334 MET D CE  1 
ATOM   1339 N N   . PHE A 1 165 ? -54.678 -20.5   36.702  1   62.38  ? 335 PHE D N   1 
ATOM   1340 C CA  . PHE A 1 165 ? -54.07  -21.692 37.284  1   61.86  ? 335 PHE D CA  1 
ATOM   1341 C C   . PHE A 1 165 ? -53.314 -22.5   36.236  1   62.33  ? 335 PHE D C   1 
ATOM   1342 O O   . PHE A 1 165 ? -52.218 -22.962 36.494  1   61.18  ? 335 PHE D O   1 
ATOM   1343 C CB  . PHE A 1 165 ? -55.145 -22.614 37.856  1   64.41  ? 335 PHE D CB  1 
ATOM   1344 C CG  . PHE A 1 165 ? -54.651 -24.004 38.205  1   63.88  ? 335 PHE D CG  1 
ATOM   1345 C CD1 . PHE A 1 165 ? -53.528 -24.19  38.997  1   63.66  ? 335 PHE D CD1 1 
ATOM   1346 C CD2 . PHE A 1 165 ? -55.307 -25.123 37.721  1   67.06  ? 335 PHE D CD2 1 
ATOM   1347 C CE1 . PHE A 1 165 ? -53.093 -25.468 39.309  1   65.02  ? 335 PHE D CE1 1 
ATOM   1348 C CE2 . PHE A 1 165 ? -54.878 -26.402 38.044  1   67.93  ? 335 PHE D CE2 1 
ATOM   1349 C CZ  . PHE A 1 165 ? -53.768 -26.571 38.828  1   66.86  ? 335 PHE D CZ  1 
ATOM   1350 N N   . LEU A 1 166 ? -53.945 -22.7   35.071  1   66.73  ? 336 LEU D N   1 
ATOM   1351 C CA  . LEU A 1 166 ? -53.408 -23.514 33.991  1   63.2   ? 336 LEU D CA  1 
ATOM   1352 C C   . LEU A 1 166 ? -52.218 -22.78  33.396  1   63.52  ? 336 LEU D C   1 
ATOM   1353 O O   . LEU A 1 166 ? -51.246 -23.409 32.971  1   64.24  ? 336 LEU D O   1 
ATOM   1354 C CB  . LEU A 1 166 ? -54.494 -23.733 32.941  1   61.92  ? 336 LEU D CB  1 
ATOM   1355 C CG  . LEU A 1 166 ? -55.675 -24.595 33.4    1   64.06  ? 336 LEU D CG  1 
ATOM   1356 C CD1 . LEU A 1 166 ? -56.778 -24.673 32.365  1   64.5   ? 336 LEU D CD1 1 
ATOM   1357 C CD2 . LEU A 1 166 ? -55.211 -25.99  33.777  1   63.79  ? 336 LEU D CD2 1 
ATOM   1358 N N   . GLY A 1 167 ? -52.329 -21.446 33.355  1   60.71  ? 337 GLY D N   1 
ATOM   1359 C CA  . GLY A 1 167 ? -51.255 -20.602 32.868  1   59.56  ? 337 GLY D CA  1 
ATOM   1360 C C   . GLY A 1 167 ? -49.978 -20.82  33.672  1   58.29  ? 337 GLY D C   1 
ATOM   1361 O O   . GLY A 1 167 ? -48.908 -20.994 33.091  1   59.11  ? 337 GLY D O   1 
ATOM   1362 N N   . GLU A 1 168 ? -50.113 -20.832 35.005  1   57.35  ? 338 GLU D N   1 
ATOM   1363 C CA  . GLU A 1 168 ? -48.96  -20.952 35.877  1   55.85  ? 338 GLU D CA  1 
ATOM   1364 C C   . GLU A 1 168 ? -48.337 -22.339 35.75   1   58.41  ? 338 GLU D C   1 
ATOM   1365 O O   . GLU A 1 168 ? -47.11  -22.475 35.852  1   60.6   ? 338 GLU D O   1 
ATOM   1366 C CB  . GLU A 1 168 ? -49.308 -20.68  37.334  1   54.24  ? 338 GLU D CB  1 
ATOM   1367 C CG  . GLU A 1 168 ? -49.35  -19.2   37.663  1   54     ? 338 GLU D CG  1 
ATOM   1368 C CD  . GLU A 1 168 ? -49.466 -18.938 39.154  1   57.43  ? 338 GLU D CD  1 
ATOM   1369 O OE1 . GLU A 1 168 ? -48.804 -19.633 39.984  1   54.83  ? 338 GLU D OE1 1 
ATOM   1370 O OE2 . GLU A 1 168 ? -50.203 -17.976 39.464  1   59.13  ? 338 GLU D OE2 1 
ATOM   1371 N N   . LEU A 1 169 ? -49.179 -23.358 35.55   1   55.43  ? 339 LEU D N   1 
ATOM   1372 C CA  . LEU A 1 169 ? -48.687 -24.711 35.376  1   55.85  ? 339 LEU D CA  1 
ATOM   1373 C C   . LEU A 1 169 ? -47.725 -24.772 34.195  1   56.43  ? 339 LEU D C   1 
ATOM   1374 O O   . LEU A 1 169 ? -46.786 -25.555 34.233  1   58.04  ? 339 LEU D O   1 
ATOM   1375 C CB  . LEU A 1 169 ? -49.831 -25.71  35.193  1   57.95  ? 339 LEU D CB  1 
ATOM   1376 C CG  . LEU A 1 169 ? -50.576 -26.161 36.459  1   58.3   ? 339 LEU D CG  1 
ATOM   1377 C CD1 . LEU A 1 169 ? -51.418 -27.372 36.101  1   60.97  ? 339 LEU D CD1 1 
ATOM   1378 C CD2 . LEU A 1 169 ? -49.686 -26.476 37.645  1   55.6   ? 339 LEU D CD2 1 
ATOM   1379 N N   . SER A 1 170 ? -47.969 -23.963 33.153  1   55.23  ? 340 SER D N   1 
ATOM   1380 C CA  . SER A 1 170 ? -47.153 -23.987 31.949  1   57.44  ? 340 SER D CA  1 
ATOM   1381 C C   . SER A 1 170 ? -45.753 -23.427 32.222  1   59.16  ? 340 SER D C   1 
ATOM   1382 O O   . SER A 1 170 ? -44.798 -23.765 31.522  1   59.59  ? 340 SER D O   1 
ATOM   1383 C CB  . SER A 1 170 ? -47.829 -23.286 30.769  1   57.1   ? 340 SER D CB  1 
ATOM   1384 O OG  . SER A 1 170 ? -47.753 -21.873 30.878  1   57.39  ? 340 SER D OG  1 
ATOM   1385 N N   . LEU A 1 171 ? -45.631 -22.542 33.226  1   60.11  ? 341 LEU D N   1 
ATOM   1386 C CA  . LEU A 1 171 ? -44.357 -21.913 33.552  1   53.74  ? 341 LEU D CA  1 
ATOM   1387 C C   . LEU A 1 171 ? -43.337 -22.983 33.93   1   52.8   ? 341 LEU D C   1 
ATOM   1388 O O   . LEU A 1 171 ? -42.147 -22.747 33.816  1   53.71  ? 341 LEU D O   1 
ATOM   1389 C CB  . LEU A 1 171 ? -44.535 -20.908 34.692  1   51.23  ? 341 LEU D CB  1 
ATOM   1390 C CG  . LEU A 1 171 ? -45.422 -19.692 34.414  1   48.25  ? 341 LEU D CG  1 
ATOM   1391 C CD1 . LEU A 1 171 ? -45.514 -18.873 35.687  1   48.43  ? 341 LEU D CD1 1 
ATOM   1392 C CD2 . LEU A 1 171 ? -44.889 -18.841 33.274  1   44.45  ? 341 LEU D CD2 1 
ATOM   1393 N N   . ILE A 1 172 ? -43.808 -24.14  34.408  1   52.01  ? 342 ILE D N   1 
ATOM   1394 C CA  . ILE A 1 172 ? -42.967 -25.105 35.094  1   53.01  ? 342 ILE D CA  1 
ATOM   1395 C C   . ILE A 1 172 ? -42.171 -25.949 34.095  1   56.81  ? 342 ILE D C   1 
ATOM   1396 O O   . ILE A 1 172 ? -41.034 -26.33  34.39   1   59.24  ? 342 ILE D O   1 
ATOM   1397 C CB  . ILE A 1 172 ? -43.828 -25.984 36.016  1   52.35  ? 342 ILE D CB  1 
ATOM   1398 C CG1 . ILE A 1 172 ? -44.524 -25.164 37.109  1   50.69  ? 342 ILE D CG1 1 
ATOM   1399 C CG2 . ILE A 1 172 ? -43.013 -27.151 36.581  1   53.25  ? 342 ILE D CG2 1 
ATOM   1400 C CD1 . ILE A 1 172 ? -43.632 -24.759 38.269  1   50.38  ? 342 ILE D CD1 1 
ATOM   1401 N N   . ASP A 1 173 ? -42.781 -26.253 32.938  1   55.61  ? 343 ASP D N   1 
ATOM   1402 C CA  . ASP A 1 173 ? -42.302 -27.293 32.053  1   56.08  ? 343 ASP D CA  1 
ATOM   1403 C C   . ASP A 1 173 ? -41.881 -26.672 30.729  1   57.77  ? 343 ASP D C   1 
ATOM   1404 O O   . ASP A 1 173 ? -42.728 -26.479 29.854  1   58.03  ? 343 ASP D O   1 
ATOM   1405 C CB  . ASP A 1 173 ? -43.392 -28.323 31.835  1   59.51  ? 343 ASP D CB  1 
ATOM   1406 C CG  . ASP A 1 173 ? -43.899 -28.987 33.106  1   63.44  ? 343 ASP D CG  1 
ATOM   1407 O OD1 . ASP A 1 173 ? -43.057 -29.601 33.801  1   62.58  ? 343 ASP D OD1 1 
ATOM   1408 O OD2 . ASP A 1 173 ? -45.127 -28.883 33.382  1   66.17  ? 343 ASP D OD2 1 
ATOM   1409 N N   . ALA A 1 174 ? -40.574 -26.395 30.588  1   55.79  ? 344 ALA D N   1 
ATOM   1410 C CA  . ALA A 1 174 ? -40.028 -25.82  29.363  1   57.45  ? 344 ALA D CA  1 
ATOM   1411 C C   . ALA A 1 174 ? -40.446 -26.67  28.168  1   59.53  ? 344 ALA D C   1 
ATOM   1412 O O   . ALA A 1 174 ? -40.732 -26.139 27.088  1   58.94  ? 344 ALA D O   1 
ATOM   1413 C CB  . ALA A 1 174 ? -38.514 -25.757 29.411  1   57.14  ? 344 ALA D CB  1 
ATOM   1414 N N   . ASP A 1 175 ? -40.386 -27.992 28.368  1   58.03  ? 345 ASP D N   1 
ATOM   1415 C CA  . ASP A 1 175 ? -40.939 -28.926 27.407  1   60.81  ? 345 ASP D CA  1 
ATOM   1416 C C   . ASP A 1 175 ? -42.33  -29.347 27.881  1   60.88  ? 345 ASP D C   1 
ATOM   1417 O O   . ASP A 1 175 ? -42.443 -30.053 28.875  1   61.74  ? 345 ASP D O   1 
ATOM   1418 C CB  . ASP A 1 175 ? -40.038 -30.13  27.195  1   62.06  ? 345 ASP D CB  1 
ATOM   1419 C CG  . ASP A 1 175 ? -40.679 -31.215 26.348  1   66.11  ? 345 ASP D CG  1 
ATOM   1420 O OD1 . ASP A 1 175 ? -41.78  -30.977 25.809  1   68.58  ? 345 ASP D OD1 1 
ATOM   1421 O OD2 . ASP A 1 175 ? -40.095 -32.296 26.269  1   67.87  ? 345 ASP D OD2 1 
ATOM   1422 N N   . PRO A 1 176 ? -43.427 -29.015 27.16   1   61.12  ? 346 PRO D N   1 
ATOM   1423 C CA  . PRO A 1 176 ? -43.349 -28.373 25.841  1   60.62  ? 346 PRO D CA  1 
ATOM   1424 C C   . PRO A 1 176 ? -43.572 -26.87  25.694  1   58.02  ? 346 PRO D C   1 
ATOM   1425 O O   . PRO A 1 176 ? -43.576 -26.377 24.579  1   61.27  ? 346 PRO D O   1 
ATOM   1426 C CB  . PRO A 1 176 ? -44.503 -29.145 25.149  1   61.55  ? 346 PRO D CB  1 
ATOM   1427 C CG  . PRO A 1 176 ? -45.575 -29.233 26.217  1   60.59  ? 346 PRO D CG  1 
ATOM   1428 C CD  . PRO A 1 176 ? -44.812 -29.358 27.534  1   59.98  ? 346 PRO D CD  1 
ATOM   1429 N N   . TYR A 1 177 ? -43.754 -26.138 26.793  1   55.72  ? 347 TYR D N   1 
ATOM   1430 C CA  . TYR A 1 177 ? -44.345 -24.808 26.724  1   53.99  ? 347 TYR D CA  1 
ATOM   1431 C C   . TYR A 1 177 ? -43.426 -23.715 26.161  1   56.14  ? 347 TYR D C   1 
ATOM   1432 O O   . TYR A 1 177 ? -43.914 -22.638 25.808  1   57.73  ? 347 TYR D O   1 
ATOM   1433 C CB  . TYR A 1 177 ? -45.014 -24.477 28.057  1   52.85  ? 347 TYR D CB  1 
ATOM   1434 C CG  . TYR A 1 177 ? -46.13  -25.462 28.348  1   58.28  ? 347 TYR D CG  1 
ATOM   1435 C CD1 . TYR A 1 177 ? -47.277 -25.501 27.554  1   60.22  ? 347 TYR D CD1 1 
ATOM   1436 C CD2 . TYR A 1 177 ? -46.024 -26.381 29.387  1   59.84  ? 347 TYR D CD2 1 
ATOM   1437 C CE1 . TYR A 1 177 ? -48.283 -26.427 27.798  1   65.3   ? 347 TYR D CE1 1 
ATOM   1438 C CE2 . TYR A 1 177 ? -47.035 -27.296 29.647  1   63.68  ? 347 TYR D CE2 1 
ATOM   1439 C CZ  . TYR A 1 177 ? -48.167 -27.331 28.844  1   64.82  ? 347 TYR D CZ  1 
ATOM   1440 O OH  . TYR A 1 177 ? -49.165 -28.234 29.082  1   65.14  ? 347 TYR D OH  1 
ATOM   1441 N N   . LEU A 1 178 ? -42.107 -23.938 26.068  1   57.58  ? 348 LEU D N   1 
ATOM   1442 C CA  . LEU A 1 178 ? -41.255 -22.969 25.383  1   56.6   ? 348 LEU D CA  1 
ATOM   1443 C C   . LEU A 1 178 ? -41.619 -22.848 23.893  1   57.43  ? 348 LEU D C   1 
ATOM   1444 O O   . LEU A 1 178 ? -41.305 -21.845 23.269  1   55.77  ? 348 LEU D O   1 
ATOM   1445 C CB  . LEU A 1 178 ? -39.76  -23.251 25.548  1   56.49  ? 348 LEU D CB  1 
ATOM   1446 C CG  . LEU A 1 178 ? -39.11  -22.889 26.892  1   57.62  ? 348 LEU D CG  1 
ATOM   1447 C CD1 . LEU A 1 178 ? -37.609 -23.174 26.834  1   55.68  ? 348 LEU D CD1 1 
ATOM   1448 C CD2 . LEU A 1 178 ? -39.324 -21.459 27.309  1   53.83  ? 348 LEU D CD2 1 
ATOM   1449 N N   . LYS A 1 179 ? -42.298 -23.836 23.296  1   62.97  ? 349 LYS D N   1 
ATOM   1450 C CA  . LYS A 1 179 ? -42.64  -23.691 21.885  1   64.4   ? 349 LYS D CA  1 
ATOM   1451 C C   . LYS A 1 179 ? -43.86  -22.792 21.666  1   67.71  ? 349 LYS D C   1 
ATOM   1452 O O   . LYS A 1 179 ? -44.034 -22.267 20.559  1   71.26  ? 349 LYS D O   1 
ATOM   1453 C CB  . LYS A 1 179 ? -42.68  -24.965 21.049  1   64.76  ? 349 LYS D CB  1 
ATOM   1454 C CG  . LYS A 1 179 ? -43.563 -26.095 21.506  1   69.08  ? 349 LYS D CG  1 
ATOM   1455 C CD  . LYS A 1 179 ? -43.218 -27.367 20.724  1   71.43  ? 349 LYS D CD  1 
ATOM   1456 C CE  . LYS A 1 179 ? -43.841 -28.612 21.295  1   73.63  ? 349 LYS D CE  1 
ATOM   1457 N NZ  . LYS A 1 179 ? -43.982 -29.712 20.331  1   78.51  ? 349 LYS D NZ  1 
ATOM   1458 N N   . TYR A 1 180 ? -44.65  -22.55  22.725  1   60.92  ? 350 TYR D N   1 
ATOM   1459 C CA  . TYR A 1 180 ? -45.86  -21.752 22.584  1   59.09  ? 350 TYR D CA  1 
ATOM   1460 C C   . TYR A 1 180 ? -45.608 -20.311 23.038  1   59.11  ? 350 TYR D C   1 
ATOM   1461 O O   . TYR A 1 180 ? -44.922 -20.086 24.037  1   61.88  ? 350 TYR D O   1 
ATOM   1462 C CB  . TYR A 1 180 ? -47.001 -22.457 23.325  1   56.74  ? 350 TYR D CB  1 
ATOM   1463 C CG  . TYR A 1 180 ? -47.243 -23.878 22.836  1   57.5   ? 350 TYR D CG  1 
ATOM   1464 C CD1 . TYR A 1 180 ? -47.657 -24.111 21.524  1   59.19  ? 350 TYR D CD1 1 
ATOM   1465 C CD2 . TYR A 1 180 ? -47.076 -24.978 23.676  1   54.87  ? 350 TYR D CD2 1 
ATOM   1466 C CE1 . TYR A 1 180 ? -47.88  -25.398 21.056  1   60.61  ? 350 TYR D CE1 1 
ATOM   1467 C CE2 . TYR A 1 180 ? -47.321 -26.262 23.22   1   57.04  ? 350 TYR D CE2 1 
ATOM   1468 C CZ  . TYR A 1 180 ? -47.717 -26.48  21.907  1   59.73  ? 350 TYR D CZ  1 
ATOM   1469 O OH  . TYR A 1 180 ? -47.947 -27.739 21.41   1   60.75  ? 350 TYR D OH  1 
ATOM   1470 N N   . LEU A 1 181 ? -46.166 -19.349 22.281  1   57.19  ? 351 LEU D N   1 
ATOM   1471 C CA  . LEU A 1 181 ? -46.162 -17.935 22.63   1   54.7   ? 351 LEU D CA  1 
ATOM   1472 C C   . LEU A 1 181 ? -47.115 -17.653 23.796  1   54.21  ? 351 LEU D C   1 
ATOM   1473 O O   . LEU A 1 181 ? -48.13  -18.316 23.97   1   54.65  ? 351 LEU D O   1 
ATOM   1474 C CB  . LEU A 1 181 ? -46.539 -17.079 21.423  1   54.41  ? 351 LEU D CB  1 
ATOM   1475 C CG  . LEU A 1 181 ? -45.456 -16.829 20.375  1   54.88  ? 351 LEU D CG  1 
ATOM   1476 C CD1 . LEU A 1 181 ? -46.11  -16.076 19.215  1   55.27  ? 351 LEU D CD1 1 
ATOM   1477 C CD2 . LEU A 1 181 ? -44.329 -16.004 20.95   1   51.58  ? 351 LEU D CD2 1 
ATOM   1478 N N   . PRO A 1 182 ? -46.827 -16.644 24.649  1   52.09  ? 352 PRO D N   1 
ATOM   1479 C CA  . PRO A 1 182 ? -47.703 -16.337 25.781  1   51.03  ? 352 PRO D CA  1 
ATOM   1480 C C   . PRO A 1 182 ? -49.177 -16.251 25.401  1   54.99  ? 352 PRO D C   1 
ATOM   1481 O O   . PRO A 1 182 ? -50.038 -16.693 26.157  1   58.56  ? 352 PRO D O   1 
ATOM   1482 C CB  . PRO A 1 182 ? -47.172 -14.987 26.255  1   47.8   ? 352 PRO D CB  1 
ATOM   1483 C CG  . PRO A 1 182 ? -45.689 -15.053 25.925  1   48.66  ? 352 PRO D CG  1 
ATOM   1484 C CD  . PRO A 1 182 ? -45.593 -15.838 24.629  1   48.9   ? 352 PRO D CD  1 
ATOM   1485 N N   . SER A 1 183 ? -49.454 -15.641 24.243  1   53.67  ? 353 SER D N   1 
ATOM   1486 C CA  . SER A 1 183 ? -50.813 -15.37  23.815  1   54.58  ? 353 SER D CA  1 
ATOM   1487 C C   . SER A 1 183 ? -51.53  -16.656 23.424  1   59.07  ? 353 SER D C   1 
ATOM   1488 O O   . SER A 1 183 ? -52.754 -16.717 23.523  1   62.13  ? 353 SER D O   1 
ATOM   1489 C CB  . SER A 1 183 ? -50.828 -14.426 22.676  1   54.38  ? 353 SER D CB  1 
ATOM   1490 O OG  . SER A 1 183 ? -50.153 -15.031 21.595  1   56.43  ? 353 SER D OG  1 
ATOM   1491 N N   . VAL A 1 184 ? -50.777 -17.634 22.892  1   60.22  ? 354 VAL D N   1 
ATOM   1492 C CA  . VAL A 1 184 ? -51.324 -18.932 22.517  1   58.23  ? 354 VAL D CA  1 
ATOM   1493 C C   . VAL A 1 184 ? -51.65  -19.721 23.784  1   58.74  ? 354 VAL D C   1 
ATOM   1494 O O   . VAL A 1 184 ? -52.748 -20.269 23.905  1   59.63  ? 354 VAL D O   1 
ATOM   1495 C CB  . VAL A 1 184 ? -50.394 -19.701 21.555  1   58.21  ? 354 VAL D CB  1 
ATOM   1496 C CG1 . VAL A 1 184 ? -50.763 -21.18  21.416  1   56.55  ? 354 VAL D CG1 1 
ATOM   1497 C CG2 . VAL A 1 184 ? -50.342 -19.033 20.185  1   58.39  ? 354 VAL D CG2 1 
ATOM   1498 N N   . ILE A 1 185 ? -50.694 -19.764 24.724  1   57.09  ? 355 ILE D N   1 
ATOM   1499 C CA  . ILE A 1 185 ? -50.927 -20.458 25.983  1   58.49  ? 355 ILE D CA  1 
ATOM   1500 C C   . ILE A 1 185 ? -52.13  -19.847 26.705  1   58.9   ? 355 ILE D C   1 
ATOM   1501 O O   . ILE A 1 185 ? -52.937 -20.586 27.249  1   60.83  ? 355 ILE D O   1 
ATOM   1502 C CB  . ILE A 1 185 ? -49.679 -20.492 26.884  1   54.36  ? 355 ILE D CB  1 
ATOM   1503 C CG1 . ILE A 1 185 ? -48.601 -21.37  26.294  1   54.47  ? 355 ILE D CG1 1 
ATOM   1504 C CG2 . ILE A 1 185 ? -50.068 -21.019 28.262  1   56.33  ? 355 ILE D CG2 1 
ATOM   1505 C CD1 . ILE A 1 185 ? -47.235 -21.15  26.922  1   50.44  ? 355 ILE D CD1 1 
ATOM   1506 N N   . ALA A 1 186 ? -52.218 -18.507 26.731  1   55.75  ? 356 ALA D N   1 
ATOM   1507 C CA  . ALA A 1 186 ? -53.277 -17.812 27.444  1   55.06  ? 356 ALA D CA  1 
ATOM   1508 C C   . ALA A 1 186 ? -54.642 -18.202 26.867  1   60.23  ? 356 ALA D C   1 
ATOM   1509 O O   . ALA A 1 186 ? -55.584 -18.48  27.619  1   59.77  ? 356 ALA D O   1 
ATOM   1510 C CB  . ALA A 1 186 ? -53.071 -16.335 27.326  1   50.75  ? 356 ALA D CB  1 
ATOM   1511 N N   . ALA A 1 187 ? -54.722 -18.221 25.525  1   60.04  ? 357 ALA D N   1 
ATOM   1512 C CA  . ALA A 1 187 ? -55.92  -18.637 24.809  1   63.91  ? 357 ALA D CA  1 
ATOM   1513 C C   . ALA A 1 187 ? -56.269 -20.076 25.156  1   66.18  ? 357 ALA D C   1 
ATOM   1514 O O   . ALA A 1 187 ? -57.426 -20.367 25.395  1   72.06  ? 357 ALA D O   1 
ATOM   1515 C CB  . ALA A 1 187 ? -55.753 -18.483 23.314  1   63.74  ? 357 ALA D CB  1 
ATOM   1516 N N   . ALA A 1 188 ? -55.272 -20.966 25.176  1   66.25  ? 358 ALA D N   1 
ATOM   1517 C CA  . ALA A 1 188 ? -55.532 -22.369 25.44   1   68.28  ? 358 ALA D CA  1 
ATOM   1518 C C   . ALA A 1 188 ? -55.955 -22.572 26.895  1   69.54  ? 358 ALA D C   1 
ATOM   1519 O O   . ALA A 1 188 ? -56.773 -23.446 27.184  1   75.52  ? 358 ALA D O   1 
ATOM   1520 C CB  . ALA A 1 188 ? -54.343 -23.22  25.055  1   66.28  ? 358 ALA D CB  1 
ATOM   1521 N N   . ALA A 1 189 ? -55.417 -21.757 27.804  1   65.53  ? 359 ALA D N   1 
ATOM   1522 C CA  . ALA A 1 189 ? -55.795 -21.848 29.207  1   67     ? 359 ALA D CA  1 
ATOM   1523 C C   . ALA A 1 189 ? -57.215 -21.315 29.392  1   70.13  ? 359 ALA D C   1 
ATOM   1524 O O   . ALA A 1 189 ? -57.969 -21.832 30.214  1   74.25  ? 359 ALA D O   1 
ATOM   1525 C CB  . ALA A 1 189 ? -54.812 -21.09  30.072  1   62.12  ? 359 ALA D CB  1 
ATOM   1526 N N   . PHE A 1 190 ? -57.566 -20.276 28.624  1   67.85  ? 360 PHE D N   1 
ATOM   1527 C CA  . PHE A 1 190 ? -58.865 -19.633 28.737  1   69     ? 360 PHE D CA  1 
ATOM   1528 C C   . PHE A 1 190 ? -59.961 -20.528 28.146  1   73.14  ? 360 PHE D C   1 
ATOM   1529 O O   . PHE A 1 190 ? -61.029 -20.653 28.733  1   72.88  ? 360 PHE D O   1 
ATOM   1530 C CB  . PHE A 1 190 ? -58.83  -18.225 28.134  1   67.05  ? 360 PHE D CB  1 
ATOM   1531 C CG  . PHE A 1 190 ? -60.173 -17.524 28.157  1   68.66  ? 360 PHE D CG  1 
ATOM   1532 C CD1 . PHE A 1 190 ? -60.795 -17.249 29.365  1   69.53  ? 360 PHE D CD1 1 
ATOM   1533 C CD2 . PHE A 1 190 ? -60.826 -17.186 26.979  1   70.92  ? 360 PHE D CD2 1 
ATOM   1534 C CE1 . PHE A 1 190 ? -62.039 -16.636 29.396  1   70.66  ? 360 PHE D CE1 1 
ATOM   1535 C CE2 . PHE A 1 190 ? -62.062 -16.559 27.015  1   71.65  ? 360 PHE D CE2 1 
ATOM   1536 C CZ  . PHE A 1 190 ? -62.664 -16.282 28.222  1   71.42  ? 360 PHE D CZ  1 
ATOM   1537 N N   . HIS A 1 191 ? -59.687 -21.166 27.001  1   73.31  ? 361 HIS D N   1 
ATOM   1538 C CA  . HIS A 1 191 ? -60.618 -22.117 26.42   1   75.98  ? 361 HIS D CA  1 
ATOM   1539 C C   . HIS A 1 191 ? -60.87  -23.291 27.362  1   78.2   ? 361 HIS D C   1 
ATOM   1540 O O   . HIS A 1 191 ? -62.004 -23.76  27.499  1   81.92  ? 361 HIS D O   1 
ATOM   1541 C CB  . HIS A 1 191 ? -60.099 -22.749 25.125  1   78.47  ? 361 HIS D CB  1 
ATOM   1542 C CG  . HIS A 1 191 ? -60.948 -23.94  24.764  1   85.91  ? 361 HIS D CG  1 
ATOM   1543 N ND1 . HIS A 1 191 ? -62.291 -23.828 24.474  1   87.11  ? 361 HIS D ND1 1 
ATOM   1544 C CD2 . HIS A 1 191 ? -60.69  -25.256 24.729  1   86.76  ? 361 HIS D CD2 1 
ATOM   1545 C CE1 . HIS A 1 191 ? -62.793 -25.024 24.223  1   90.52  ? 361 HIS D CE1 1 
ATOM   1546 N NE2 . HIS A 1 191 ? -61.84  -25.904 24.376  1   89.53  ? 361 HIS D NE2 1 
ATOM   1547 N N   . LEU A 1 192 ? -59.785 -23.803 27.944  1   76.58  ? 362 LEU D N   1 
ATOM   1548 C CA  . LEU A 1 192 ? -59.854 -25.014 28.735  1   78.14  ? 362 LEU D CA  1 
ATOM   1549 C C   . LEU A 1 192 ? -60.563 -24.736 30.058  1   78.46  ? 362 LEU D C   1 
ATOM   1550 O O   . LEU A 1 192 ? -61.269 -25.604 30.57   1   81.26  ? 362 LEU D O   1 
ATOM   1551 C CB  . LEU A 1 192 ? -58.427 -25.518 28.921  1   76.96  ? 362 LEU D CB  1 
ATOM   1552 C CG  . LEU A 1 192 ? -58.27  -26.829 29.691  1   79.21  ? 362 LEU D CG  1 
ATOM   1553 C CD1 . LEU A 1 192 ? -59.193 -27.921 29.151  1   83.44  ? 362 LEU D CD1 1 
ATOM   1554 C CD2 . LEU A 1 192 ? -56.82  -27.262 29.667  1   76.81  ? 362 LEU D CD2 1 
ATOM   1555 N N   . ALA A 1 193 ? -60.381 -23.52  30.586  1   76.14  ? 363 ALA D N   1 
ATOM   1556 C CA  . ALA A 1 193 ? -61.016 -23.117 31.834  1   78.76  ? 363 ALA D CA  1 
ATOM   1557 C C   . ALA A 1 193 ? -62.513 -22.877 31.619  1   82.96  ? 363 ALA D C   1 
ATOM   1558 O O   . ALA A 1 193 ? -63.34  -23.252 32.45   1   83.13  ? 363 ALA D O   1 
ATOM   1559 C CB  . ALA A 1 193 ? -60.342 -21.892 32.397  1   72.45  ? 363 ALA D CB  1 
ATOM   1560 N N   . LEU A 1 194 ? -62.83  -22.237 30.484  1   84.82  ? 364 LEU D N   1 
ATOM   1561 C CA  . LEU A 1 194 ? -64.185 -21.926 30.069  1   86.67  ? 364 LEU D CA  1 
ATOM   1562 C C   . LEU A 1 194 ? -64.951 -23.238 29.884  1   91.31  ? 364 LEU D C   1 
ATOM   1563 O O   . LEU A 1 194 ? -66.031 -23.416 30.449  1   98.08  ? 364 LEU D O   1 
ATOM   1564 C CB  . LEU A 1 194 ? -64.086 -21.106 28.779  1   86.56  ? 364 LEU D CB  1 
ATOM   1565 C CG  . LEU A 1 194 ? -65.205 -20.099 28.475  1   92.53  ? 364 LEU D CG  1 
ATOM   1566 C CD1 . LEU A 1 194 ? -65.399 -19.088 29.595  1   91.22  ? 364 LEU D CD1 1 
ATOM   1567 C CD2 . LEU A 1 194 ? -64.935 -19.363 27.163  1   90.65  ? 364 LEU D CD2 1 
ATOM   1568 N N   . TYR A 1 195 ? -64.357 -24.176 29.132  1   90.02  ? 365 TYR D N   1 
ATOM   1569 C CA  . TYR A 1 195 ? -64.997 -25.439 28.811  1   89.93  ? 365 TYR D CA  1 
ATOM   1570 C C   . TYR A 1 195 ? -65.254 -26.248 30.077  1   90.35  ? 365 TYR D C   1 
ATOM   1571 O O   . TYR A 1 195 ? -66.266 -26.922 30.166  1   94.58  ? 365 TYR D O   1 
ATOM   1572 C CB  . TYR A 1 195 ? -64.114 -26.243 27.858  1   90.8   ? 365 TYR D CB  1 
ATOM   1573 C CG  . TYR A 1 195 ? -64.704 -27.553 27.353  1   94.9   ? 365 TYR D CG  1 
ATOM   1574 C CD1 . TYR A 1 195 ? -65.927 -27.603 26.68   1   98.55  ? 365 TYR D CD1 1 
ATOM   1575 C CD2 . TYR A 1 195 ? -64.025 -28.748 27.561  1   96.01  ? 365 TYR D CD2 1 
ATOM   1576 C CE1 . TYR A 1 195 ? -66.435 -28.81  26.219  1   103.45 ? 365 TYR D CE1 1 
ATOM   1577 C CE2 . TYR A 1 195 ? -64.517 -29.958 27.098  1   100.02 ? 365 TYR D CE2 1 
ATOM   1578 C CZ  . TYR A 1 195 ? -65.729 -29.988 26.429  1   104.2  ? 365 TYR D CZ  1 
ATOM   1579 O OH  . TYR A 1 195 ? -66.216 -31.191 25.997  1   110.51 ? 365 TYR D OH  1 
ATOM   1580 N N   . THR A 1 196 ? -64.342 -26.173 31.05   1   89.66  ? 366 THR D N   1 
ATOM   1581 C CA  . THR A 1 196 ? -64.404 -27.015 32.239  1   89.85  ? 366 THR D CA  1 
ATOM   1582 C C   . THR A 1 196 ? -65.523 -26.577 33.183  1   91.25  ? 366 THR D C   1 
ATOM   1583 O O   . THR A 1 196 ? -66.137 -27.425 33.823  1   91.44  ? 366 THR D O   1 
ATOM   1584 C CB  . THR A 1 196 ? -63.067 -27.028 32.98   1   86.17  ? 366 THR D CB  1 
ATOM   1585 O OG1 . THR A 1 196 ? -62.039 -27.419 32.069  1   82.91  ? 366 THR D OG1 1 
ATOM   1586 C CG2 . THR A 1 196 ? -63.113 -27.906 34.223  1   85.59  ? 366 THR D CG2 1 
ATOM   1587 N N   . VAL A 1 197 ? -65.751 -25.26  33.299  1   90.81  ? 367 VAL D N   1 
ATOM   1588 C CA  . VAL A 1 197 ? -66.644 -24.733 34.319  1   93.56  ? 367 VAL D CA  1 
ATOM   1589 C C   . VAL A 1 197 ? -68.028 -24.462 33.726  1   97.54  ? 367 VAL D C   1 
ATOM   1590 O O   . VAL A 1 197 ? -69.039 -24.826 34.329  1   98.63  ? 367 VAL D O   1 
ATOM   1591 C CB  . VAL A 1 197 ? -66.066 -23.475 34.986  1   90.67  ? 367 VAL D CB  1 
ATOM   1592 C CG1 . VAL A 1 197 ? -66.972 -22.979 36.105  1   91.92  ? 367 VAL D CG1 1 
ATOM   1593 C CG2 . VAL A 1 197 ? -64.663 -23.725 35.519  1   89.33  ? 367 VAL D CG2 1 
ATOM   1594 N N   . THR A 1 198 ? -68.059 -23.796 32.561  1   97.22  ? 368 THR D N   1 
ATOM   1595 C CA  . THR A 1 198 ? -69.31  -23.474 31.885  1   98.88  ? 368 THR D CA  1 
ATOM   1596 C C   . THR A 1 198 ? -69.766 -24.637 31.004  1   100.54 ? 368 THR D C   1 
ATOM   1597 O O   . THR A 1 198 ? -70.859 -25.153 31.198  1   108.01 ? 368 THR D O   1 
ATOM   1598 C CB  . THR A 1 198 ? -69.201 -22.171 31.087  1   94.81  ? 368 THR D CB  1 
ATOM   1599 O OG1 . THR A 1 198 ? -68.476 -22.434 29.888  1   92.5   ? 368 THR D OG1 1 
ATOM   1600 C CG2 . THR A 1 198 ? -68.577 -21.051 31.898  1   89.4   ? 368 THR D CG2 1 
ATOM   1601 N N   . GLY A 1 199 ? -68.925 -25.019 30.032  1   99.15  ? 369 GLY D N   1 
ATOM   1602 C CA  . GLY A 1 199 ? -69.307 -25.876 28.919  1   99.69  ? 369 GLY D CA  1 
ATOM   1603 C C   . GLY A 1 199 ? -69.032 -25.192 27.578  1   100.21 ? 369 GLY D C   1 
ATOM   1604 O O   . GLY A 1 199 ? -68.762 -25.87  26.578  1   96.12  ? 369 GLY D O   1 
ATOM   1605 N N   . GLN A 1 200 ? -69.11  -23.844 27.583  1   102.88 ? 370 GLN D N   1 
ATOM   1606 C CA  . GLN A 1 200 ? -68.871 -22.996 26.42   1   103.8  ? 370 GLN D CA  1 
ATOM   1607 C C   . GLN A 1 200 ? -67.412 -23.109 26.001  1   98.48  ? 370 GLN D C   1 
ATOM   1608 O O   . GLN A 1 200 ? -66.565 -23.453 26.819  1   95.62  ? 370 GLN D O   1 
ATOM   1609 C CB  . GLN A 1 200 ? -69.172 -21.511 26.654  1   106.83 ? 370 GLN D CB  1 
ATOM   1610 C CG  . GLN A 1 200 ? -70.612 -21.093 26.375  1   122.87 ? 370 GLN D CG  1 
ATOM   1611 C CD  . GLN A 1 200 ? -71.478 -21.011 27.615  1   132.95 ? 370 GLN D CD  1 
ATOM   1612 O OE1 . GLN A 1 200 ? -71.081 -20.382 28.608  1   137.54 ? 370 GLN D OE1 1 
ATOM   1613 N NE2 . GLN A 1 200 ? -72.657 -21.632 27.569  1   120.83 ? 370 GLN D NE2 1 
ATOM   1614 N N   . SER A 1 201 ? -67.151 -22.779 24.732  1   97.33  ? 371 SER D N   1 
ATOM   1615 C CA  . SER A 1 201 ? -65.819 -22.808 24.15   1   95.31  ? 371 SER D CA  1 
ATOM   1616 C C   . SER A 1 201 ? -65.273 -21.392 23.947  1   93.91  ? 371 SER D C   1 
ATOM   1617 O O   . SER A 1 201 ? -65.893 -20.399 24.335  1   93.45  ? 371 SER D O   1 
ATOM   1618 C CB  . SER A 1 201 ? -65.821 -23.594 22.863  1   95.21  ? 371 SER D CB  1 
ATOM   1619 O OG  . SER A 1 201 ? -66.194 -24.944 23.099  1   99.41  ? 371 SER D OG  1 
ATOM   1620 N N   . TRP A 1 202 ? -64.057 -21.336 23.383  1   92.51  ? 372 TRP D N   1 
ATOM   1621 C CA  . TRP A 1 202 ? -63.408 -20.144 22.849  1   87.88  ? 372 TRP D CA  1 
ATOM   1622 C C   . TRP A 1 202 ? -64.419 -19.361 22.009  1   89.12  ? 372 TRP D C   1 
ATOM   1623 O O   . TRP A 1 202 ? -64.927 -19.896 21.016  1   94.78  ? 372 TRP D O   1 
ATOM   1624 C CB  . TRP A 1 202 ? -62.217 -20.628 22.003  1   84.56  ? 372 TRP D CB  1 
ATOM   1625 C CG  . TRP A 1 202 ? -61.304 -19.579 21.429  1   80.97  ? 372 TRP D CG  1 
ATOM   1626 C CD1 . TRP A 1 202 ? -61.121 -19.302 20.105  1   79.75  ? 372 TRP D CD1 1 
ATOM   1627 C CD2 . TRP A 1 202 ? -60.418 -18.692 22.153  1   77.45  ? 372 TRP D CD2 1 
ATOM   1628 N NE1 . TRP A 1 202 ? -60.198 -18.298 19.958  1   78.4   ? 372 TRP D NE1 1 
ATOM   1629 C CE2 . TRP A 1 202 ? -59.744 -17.903 21.19   1   75.34  ? 372 TRP D CE2 1 
ATOM   1630 C CE3 . TRP A 1 202 ? -60.125 -18.482 23.511  1   76.46  ? 372 TRP D CE3 1 
ATOM   1631 C CZ2 . TRP A 1 202 ? -58.801 -16.935 21.547  1   69.08  ? 372 TRP D CZ2 1 
ATOM   1632 C CZ3 . TRP A 1 202 ? -59.2   -17.518 23.867  1   70.06  ? 372 TRP D CZ3 1 
ATOM   1633 C CH2 . TRP A 1 202 ? -58.554 -16.753 22.893  1   67.36  ? 372 TRP D CH2 1 
ATOM   1634 N N   . PRO A 1 203 ? -64.779 -18.106 22.387  1   84.83  ? 373 PRO D N   1 
ATOM   1635 C CA  . PRO A 1 203 ? -65.792 -17.332 21.659  1   86.38  ? 373 PRO D CA  1 
ATOM   1636 C C   . PRO A 1 203 ? -65.308 -16.692 20.361  1   85.58  ? 373 PRO D C   1 
ATOM   1637 O O   . PRO A 1 203 ? -64.121 -16.382 20.203  1   82.56  ? 373 PRO D O   1 
ATOM   1638 C CB  . PRO A 1 203 ? -66.163 -16.254 22.684  1   86.19  ? 373 PRO D CB  1 
ATOM   1639 C CG  . PRO A 1 203 ? -64.836 -15.968 23.347  1   80.69  ? 373 PRO D CG  1 
ATOM   1640 C CD  . PRO A 1 203 ? -64.251 -17.361 23.536  1   81.69  ? 373 PRO D CD  1 
ATOM   1641 N N   . GLU A 1 204 ? -66.281 -16.43  19.484  1   88.21  ? 374 GLU D N   1 
ATOM   1642 C CA  . GLU A 1 204 ? -66.07  -15.894 18.149  1   88.93  ? 374 GLU D CA  1 
ATOM   1643 C C   . GLU A 1 204 ? -65.419 -14.51  18.256  1   85.58  ? 374 GLU D C   1 
ATOM   1644 O O   . GLU A 1 204 ? -64.615 -14.127 17.402  1   84.39  ? 374 GLU D O   1 
ATOM   1645 C CB  . GLU A 1 204 ? -67.422 -15.935 17.425  1   90.64  ? 374 GLU D CB  1 
ATOM   1646 C CG  . GLU A 1 204 ? -67.35  -15.551 15.948  1   93.89  ? 374 GLU D CG  1 
ATOM   1647 C CD  . GLU A 1 204 ? -66.231 -16.205 15.146  1   95.25  ? 374 GLU D CD  1 
ATOM   1648 O OE1 . GLU A 1 204 ? -66.044 -17.445 15.228  1   96.84  ? 374 GLU D OE1 1 
ATOM   1649 O OE2 . GLU A 1 204 ? -65.533 -15.471 14.421  1   93.93  ? 374 GLU D OE2 1 
ATOM   1650 N N   . SER A 1 205 ? -65.777 -13.776 19.32   1   81.47  ? 375 SER D N   1 
ATOM   1651 C CA  . SER A 1 205 ? -65.299 -12.422 19.546  1   78.77  ? 375 SER D CA  1 
ATOM   1652 C C   . SER A 1 205 ? -63.786 -12.412 19.782  1   74.44  ? 375 SER D C   1 
ATOM   1653 O O   . SER A 1 205 ? -63.115 -11.425 19.482  1   71.21  ? 375 SER D O   1 
ATOM   1654 C CB  . SER A 1 205 ? -66.038 -11.788 20.704  1   79.44  ? 375 SER D CB  1 
ATOM   1655 O OG  . SER A 1 205 ? -65.663 -12.385 21.94   1   80.18  ? 375 SER D OG  1 
ATOM   1656 N N   . LEU A 1 206 ? -63.273 -13.51  20.349  1   73.71  ? 376 LEU D N   1 
ATOM   1657 C CA  . LEU A 1 206 ? -61.848 -13.678 20.603  1   72.83  ? 376 LEU D CA  1 
ATOM   1658 C C   . LEU A 1 206 ? -61.151 -14.277 19.38   1   73.91  ? 376 LEU D C   1 
ATOM   1659 O O   . LEU A 1 206 ? -59.975 -13.984 19.154  1   71.69  ? 376 LEU D O   1 
ATOM   1660 C CB  . LEU A 1 206 ? -61.598 -14.501 21.863  1   69.75  ? 376 LEU D CB  1 
ATOM   1661 C CG  . LEU A 1 206 ? -61.816 -13.773 23.193  1   69.23  ? 376 LEU D CG  1 
ATOM   1662 C CD1 . LEU A 1 206 ? -61.684 -14.715 24.374  1   68.07  ? 376 LEU D CD1 1 
ATOM   1663 C CD2 . LEU A 1 206 ? -60.852 -12.608 23.322  1   68.04  ? 376 LEU D CD2 1 
ATOM   1664 N N   . VAL A 1 207 ? -61.879 -15.085 18.593  1   73.45  ? 377 VAL D N   1 
ATOM   1665 C CA  . VAL A 1 207 ? -61.373 -15.486 17.292  1   74.33  ? 377 VAL D CA  1 
ATOM   1666 C C   . VAL A 1 207 ? -61.096 -14.222 16.48   1   75.49  ? 377 VAL D C   1 
ATOM   1667 O O   . VAL A 1 207 ? -60.036 -14.089 15.868  1   73.65  ? 377 VAL D O   1 
ATOM   1668 C CB  . VAL A 1 207 ? -62.317 -16.45  16.544  1   78.95  ? 377 VAL D CB  1 
ATOM   1669 C CG1 . VAL A 1 207 ? -61.878 -16.712 15.104  1   78.49  ? 377 VAL D CG1 1 
ATOM   1670 C CG2 . VAL A 1 207 ? -62.479 -17.767 17.292  1   80.3   ? 377 VAL D CG2 1 
ATOM   1671 N N   . GLN A 1 208 ? -62.054 -13.288 16.501  1   79.51  ? 378 GLN D N   1 
ATOM   1672 C CA  . GLN A 1 208 ? -61.937 -12.036 15.762  1   83.53  ? 378 GLN D CA  1 
ATOM   1673 C C   . GLN A 1 208 ? -60.803 -11.171 16.325  1   79.61  ? 378 GLN D C   1 
ATOM   1674 O O   . GLN A 1 208 ? -60.123 -10.472 15.578  1   79.03  ? 378 GLN D O   1 
ATOM   1675 C CB  . GLN A 1 208 ? -63.282 -11.306 15.763  1   88.11  ? 378 GLN D CB  1 
ATOM   1676 C CG  . GLN A 1 208 ? -64.316 -11.911 14.822  1   94.46  ? 378 GLN D CG  1 
ATOM   1677 C CD  . GLN A 1 208 ? -63.946 -11.678 13.375  1   99.87  ? 378 GLN D CD  1 
ATOM   1678 O OE1 . GLN A 1 208 ? -63.827 -12.609 12.564  1   96.39  ? 378 GLN D OE1 1 
ATOM   1679 N NE2 . GLN A 1 208 ? -63.709 -10.41  13.067  1   103.4  ? 378 GLN D NE2 1 
ATOM   1680 N N   . LYS A 1 209 ? -60.608 -11.203 17.65   1   77.67  ? 379 LYS D N   1 
ATOM   1681 C CA  . LYS A 1 209 ? -59.572 -10.394 18.271  1   73.94  ? 379 LYS D CA  1 
ATOM   1682 C C   . LYS A 1 209 ? -58.197 -10.941 17.892  1   71.7   ? 379 LYS D C   1 
ATOM   1683 O O   . LYS A 1 209 ? -57.352 -10.195 17.405  1   71.81  ? 379 LYS D O   1 
ATOM   1684 C CB  . LYS A 1 209 ? -59.696 -10.343 19.8    1   74.45  ? 379 LYS D CB  1 
ATOM   1685 C CG  . LYS A 1 209 ? -58.787 -9.314  20.492  1   70.91  ? 379 LYS D CG  1 
ATOM   1686 C CD  . LYS A 1 209 ? -58.858 -9.387  22.015  1   72.44  ? 379 LYS D CD  1 
ATOM   1687 C CE  . LYS A 1 209 ? -57.998 -8.397  22.752  1   66.5   ? 379 LYS D CE  1 
ATOM   1688 N NZ  . LYS A 1 209 ? -58.428 -7.022  22.482  1   65.75  ? 379 LYS D NZ  1 
ATOM   1689 N N   . THR A 1 210 ? -58.011 -12.252 18.104  1   68.26  ? 380 THR D N   1 
ATOM   1690 C CA  . THR A 1 210 ? -56.704 -12.892 18.142  1   64.64  ? 380 THR D CA  1 
ATOM   1691 C C   . THR A 1 210 ? -56.286 -13.438 16.778  1   65.5   ? 380 THR D C   1 
ATOM   1692 O O   . THR A 1 210 ? -55.092 -13.57  16.506  1   65.33  ? 380 THR D O   1 
ATOM   1693 C CB  . THR A 1 210 ? -56.729 -14.022 19.168  1   65.47  ? 380 THR D CB  1 
ATOM   1694 O OG1 . THR A 1 210 ? -57.657 -15.014 18.714  1   69.02  ? 380 THR D OG1 1 
ATOM   1695 C CG2 . THR A 1 210 ? -57.066 -13.515 20.56   1   64.54  ? 380 THR D CG2 1 
ATOM   1696 N N   . GLY A 1 211 ? -57.256 -13.815 15.94   1   65.92  ? 381 GLY D N   1 
ATOM   1697 C CA  . GLY A 1 211 ? -56.933 -14.566 14.743  1   65.07  ? 381 GLY D CA  1 
ATOM   1698 C C   . GLY A 1 211 ? -56.702 -16.044 15.047  1   65.28  ? 381 GLY D C   1 
ATOM   1699 O O   . GLY A 1 211 ? -56.464 -16.819 14.127  1   66.16  ? 381 GLY D O   1 
ATOM   1700 N N   . TYR A 1 212 ? -56.8   -16.428 16.323  1   66.14  ? 382 TYR D N   1 
ATOM   1701 C CA  . TYR A 1 212 ? -56.619 -17.811 16.755  1   71.02  ? 382 TYR D CA  1 
ATOM   1702 C C   . TYR A 1 212 ? -57.955 -18.544 16.672  1   76.39  ? 382 TYR D C   1 
ATOM   1703 O O   . TYR A 1 212 ? -58.949 -18.05  17.197  1   79.04  ? 382 TYR D O   1 
ATOM   1704 C CB  . TYR A 1 212 ? -56.095 -17.936 18.196  1   69.48  ? 382 TYR D CB  1 
ATOM   1705 C CG  . TYR A 1 212 ? -54.728 -17.326 18.461  1   66.82  ? 382 TYR D CG  1 
ATOM   1706 C CD1 . TYR A 1 212 ? -53.827 -17.099 17.42   1   67.84  ? 382 TYR D CD1 1 
ATOM   1707 C CD2 . TYR A 1 212 ? -54.35  -16.949 19.752  1   65.49  ? 382 TYR D CD2 1 
ATOM   1708 C CE1 . TYR A 1 212 ? -52.593 -16.508 17.674  1   69.16  ? 382 TYR D CE1 1 
ATOM   1709 C CE2 . TYR A 1 212 ? -53.127 -16.335 20.012  1   63.77  ? 382 TYR D CE2 1 
ATOM   1710 C CZ  . TYR A 1 212 ? -52.243 -16.127 18.966  1   64.68  ? 382 TYR D CZ  1 
ATOM   1711 O OH  . TYR A 1 212 ? -51.022 -15.568 19.18   1   61.83  ? 382 TYR D OH  1 
ATOM   1712 N N   . THR A 1 213 ? -57.967 -19.715 16.017  1   78.68  ? 383 THR D N   1 
ATOM   1713 C CA  . THR A 1 213 ? -59.133 -20.585 16.037  1   82.47  ? 383 THR D CA  1 
ATOM   1714 C C   . THR A 1 213 ? -58.85  -21.768 16.96   1   82.58  ? 383 THR D C   1 
ATOM   1715 O O   . THR A 1 213 ? -57.737 -21.919 17.463  1   83.78  ? 383 THR D O   1 
ATOM   1716 C CB  . THR A 1 213 ? -59.514 -21.015 14.62   1   87.63  ? 383 THR D CB  1 
ATOM   1717 O OG1 . THR A 1 213 ? -58.574 -21.992 14.179  1   89.64  ? 383 THR D OG1 1 
ATOM   1718 C CG2 . THR A 1 213 ? -59.576 -19.836 13.662  1   87.78  ? 383 THR D CG2 1 
ATOM   1719 N N   . LEU A 1 214 ? -59.874 -22.582 17.221  1   84.7   ? 384 LEU D N   1 
ATOM   1720 C CA  . LEU A 1 214 ? -59.669 -23.77  18.031  1   86.28  ? 384 LEU D CA  1 
ATOM   1721 C C   . LEU A 1 214 ? -58.8   -24.759 17.261  1   87.62  ? 384 LEU D C   1 
ATOM   1722 O O   . LEU A 1 214 ? -58.132 -25.597 17.861  1   85.61  ? 384 LEU D O   1 
ATOM   1723 C CB  . LEU A 1 214 ? -60.998 -24.394 18.451  1   87.9   ? 384 LEU D CB  1 
ATOM   1724 C CG  . LEU A 1 214 ? -61.566 -23.938 19.798  1   86.25  ? 384 LEU D CG  1 
ATOM   1725 C CD1 . LEU A 1 214 ? -62.996 -24.373 19.966  1   88.13  ? 384 LEU D CD1 1 
ATOM   1726 C CD2 . LEU A 1 214 ? -60.759 -24.54  20.919  1   86.82  ? 384 LEU D CD2 1 
ATOM   1727 N N   . GLU A 1 215 ? -58.812 -24.641 15.928  1   90.07  ? 385 GLU D N   1 
ATOM   1728 C CA  . GLU A 1 215 ? -57.92  -25.412 15.074  1   93.07  ? 385 GLU D CA  1 
ATOM   1729 C C   . GLU A 1 215 ? -56.456 -25.075 15.402  1   89.76  ? 385 GLU D C   1 
ATOM   1730 O O   . GLU A 1 215 ? -55.665 -25.967 15.698  1   87.52  ? 385 GLU D O   1 
ATOM   1731 C CB  . GLU A 1 215 ? -58.29  -25.2   13.604  1   94.36  ? 385 GLU D CB  1 
ATOM   1732 C CG  . GLU A 1 215 ? -57.886 -26.359 12.696  1   102.57 ? 385 GLU D CG  1 
ATOM   1733 C CD  . GLU A 1 215 ? -57.758 -26.025 11.215  1   108.19 ? 385 GLU D CD  1 
ATOM   1734 O OE1 . GLU A 1 215 ? -58.56  -26.563 10.417  1   109.81 ? 385 GLU D OE1 1 
ATOM   1735 O OE2 . GLU A 1 215 ? -56.851 -25.233 10.854  1   107.49 ? 385 GLU D OE2 1 
ATOM   1736 N N   . THR A 1 216 ? -56.092 -23.783 15.346  1   84.98  ? 386 THR D N   1 
ATOM   1737 C CA  . THR A 1 216 ? -54.704 -23.383 15.492  1   83.83  ? 386 THR D CA  1 
ATOM   1738 C C   . THR A 1 216 ? -54.263 -23.54  16.946  1   83.2   ? 386 THR D C   1 
ATOM   1739 O O   . THR A 1 216 ? -53.067 -23.624 17.217  1   82.49  ? 386 THR D O   1 
ATOM   1740 C CB  . THR A 1 216 ? -54.469 -21.961 14.978  1   83.21  ? 386 THR D CB  1 
ATOM   1741 O OG1 . THR A 1 216 ? -55.104 -21.065 15.888  1   79.26  ? 386 THR D OG1 1 
ATOM   1742 C CG2 . THR A 1 216 ? -54.928 -21.773 13.541  1   83.73  ? 386 THR D CG2 1 
ATOM   1743 N N   . LEU A 1 217 ? -55.234 -23.563 17.871  1   80.82  ? 387 LEU D N   1 
ATOM   1744 C CA  . LEU A 1 217 ? -54.956 -23.759 19.286  1   75.71  ? 387 LEU D CA  1 
ATOM   1745 C C   . LEU A 1 217 ? -54.891 -25.245 19.63   1   77.66  ? 387 LEU D C   1 
ATOM   1746 O O   . LEU A 1 217 ? -54.719 -25.582 20.789  1   79.73  ? 387 LEU D O   1 
ATOM   1747 C CB  . LEU A 1 217 ? -56.041 -23.098 20.135  1   71.48  ? 387 LEU D CB  1 
ATOM   1748 C CG  . LEU A 1 217 ? -56.053 -21.576 20.205  1   68.55  ? 387 LEU D CG  1 
ATOM   1749 C CD1 . LEU A 1 217 ? -57.314 -21.183 20.982  1   70.19  ? 387 LEU D CD1 1 
ATOM   1750 C CD2 . LEU A 1 217 ? -54.793 -21.02  20.87   1   66     ? 387 LEU D CD2 1 
ATOM   1751 N N   . LYS A 1 218 ? -55.088 -26.133 18.657  1   81.35  ? 388 LYS D N   1 
ATOM   1752 C CA  . LYS A 1 218 ? -55.25  -27.552 18.953  1   82.5   ? 388 LYS D CA  1 
ATOM   1753 C C   . LYS A 1 218 ? -53.996 -28.115 19.624  1   82.12  ? 388 LYS D C   1 
ATOM   1754 O O   . LYS A 1 218 ? -54.095 -28.674 20.714  1   83.31  ? 388 LYS D O   1 
ATOM   1755 C CB  . LYS A 1 218 ? -55.667 -28.363 17.721  1   84.28  ? 388 LYS D CB  1 
ATOM   1756 C CG  . LYS A 1 218 ? -55.897 -29.849 17.957  1   86.09  ? 388 LYS D CG  1 
ATOM   1757 C CD  . LYS A 1 218 ? -56.439 -30.599 16.742  1   89.97  ? 388 LYS D CD  1 
ATOM   1758 C CE  . LYS A 1 218 ? -56.538 -32.082 16.969  1   93.65  ? 388 LYS D CE  1 
ATOM   1759 N NZ  . LYS A 1 218 ? -57.177 -32.836 15.887  1   98.89  ? 388 LYS D NZ  1 
ATOM   1760 N N   . PRO A 1 219 ? -52.785 -27.982 19.026  1   80.46  ? 389 PRO D N   1 
ATOM   1761 C CA  . PRO A 1 219 ? -51.578 -28.552 19.639  1   78.87  ? 389 PRO D CA  1 
ATOM   1762 C C   . PRO A 1 219 ? -51.381 -28.119 21.092  1   79.6   ? 389 PRO D C   1 
ATOM   1763 O O   . PRO A 1 219 ? -51.203 -28.976 21.963  1   82.37  ? 389 PRO D O   1 
ATOM   1764 C CB  . PRO A 1 219 ? -50.419 -28.115 18.72   1   77.42  ? 389 PRO D CB  1 
ATOM   1765 C CG  . PRO A 1 219 ? -51.106 -27.778 17.393  1   78.89  ? 389 PRO D CG  1 
ATOM   1766 C CD  . PRO A 1 219 ? -52.511 -27.282 17.751  1   77.98  ? 389 PRO D CD  1 
ATOM   1767 N N   . CYS A 1 220 ? -51.41  -26.812 21.362  1   76.7   ? 390 CYS D N   1 
ATOM   1768 C CA  . CYS A 1 220 ? -51.159 -26.31  22.739  1   73.63  ? 390 CYS D CA  1 
ATOM   1769 C C   . CYS A 1 220 ? -52.235 -26.831 23.693  1   72.89  ? 390 CYS D C   1 
ATOM   1770 O O   . CYS A 1 220 ? -51.897 -27.164 24.839  1   70.14  ? 390 CYS D O   1 
ATOM   1771 C CB  . CYS A 1 220 ? -51.155 -24.786 22.78   1   74.57  ? 390 CYS D CB  1 
ATOM   1772 S SG  . CYS A 1 220 ? -50.728 -24.084 24.393  1   70.52  ? 390 CYS D SG  1 
ATOM   1773 N N   . LEU A 1 221 ? -53.473 -26.915 23.223  1   76.24  ? 391 LEU D N   1 
ATOM   1774 C CA  . LEU A 1 221 ? -54.578 -27.325 24.123  1   79.57  ? 391 LEU D CA  1 
ATOM   1775 C C   . LEU A 1 221 ? -54.401 -28.793 24.538  1   80.32  ? 391 LEU D C   1 
ATOM   1776 O O   . LEU A 1 221 ? -54.762 -29.132 25.677  1   79.75  ? 391 LEU D O   1 
ATOM   1777 C CB  . LEU A 1 221 ? -55.923 -27.065 23.457  1   85.11  ? 391 LEU D CB  1 
ATOM   1778 C CG  . LEU A 1 221 ? -56.24  -25.592 23.2    1   89.7   ? 391 LEU D CG  1 
ATOM   1779 C CD1 . LEU A 1 221 ? -57.521 -25.439 22.408  1   91.53  ? 391 LEU D CD1 1 
ATOM   1780 C CD2 . LEU A 1 221 ? -56.307 -24.848 24.518  1   88.05  ? 391 LEU D CD2 1 
ATOM   1781 N N   . LEU A 1 222 ? -53.83  -29.607 23.658  1   80.76  ? 392 LEU D N   1 
ATOM   1782 C CA  . LEU A 1 222 ? -53.611 -31.036 23.984  1   83.51  ? 392 LEU D CA  1 
ATOM   1783 C C   . LEU A 1 222 ? -52.549 -31.146 25.079  1   81.94  ? 392 LEU D C   1 
ATOM   1784 O O   . LEU A 1 222 ? -52.771 -31.893 26.045  1   82.43  ? 392 LEU D O   1 
ATOM   1785 C CB  . LEU A 1 222 ? -53.209 -31.785 22.718  1   84.4   ? 392 LEU D CB  1 
ATOM   1786 C CG  . LEU A 1 222 ? -54.29  -31.88  21.638  1   86.42  ? 392 LEU D CG  1 
ATOM   1787 C CD1 . LEU A 1 222 ? -53.744 -32.441 20.34   1   84.95  ? 392 LEU D CD1 1 
ATOM   1788 C CD2 . LEU A 1 222 ? -55.469 -32.697 22.125  1   87.17  ? 392 LEU D CD2 1 
ATOM   1789 N N   . ASP A 1 223 ? -51.448 -30.414 24.927  1   79.74  ? 393 ASP D N   1 
ATOM   1790 C CA  . ASP A 1 223 ? -50.366 -30.43  25.947  1   74.45  ? 393 ASP D CA  1 
ATOM   1791 C C   . ASP A 1 223 ? -50.937 -29.918 27.269  1   71.65  ? 393 ASP D C   1 
ATOM   1792 O O   . ASP A 1 223 ? -50.641 -30.524 28.31   1   72.51  ? 393 ASP D O   1 
ATOM   1793 C CB  . ASP A 1 223 ? -49.154 -29.656 25.456  1   70.58  ? 393 ASP D CB  1 
ATOM   1794 C CG  . ASP A 1 223 ? -48.35  -30.313 24.346  1   71.32  ? 393 ASP D CG  1 
ATOM   1795 O OD1 . ASP A 1 223 ? -48.199 -31.548 24.388  1   75.68  ? 393 ASP D OD1 1 
ATOM   1796 O OD2 . ASP A 1 223 ? -47.873 -29.579 23.46   1   68.58  ? 393 ASP D OD2 1 
ATOM   1797 N N   . LEU A 1 224 ? -51.736 -28.855 27.222  1   66.69  ? 394 LEU D N   1 
ATOM   1798 C CA  . LEU A 1 224 ? -52.282 -28.255 28.464  1   65.51  ? 394 LEU D CA  1 
ATOM   1799 C C   . LEU A 1 224 ? -53.27  -29.235 29.087  1   69.26  ? 394 LEU D C   1 
ATOM   1800 O O   . LEU A 1 224 ? -53.27  -29.372 30.319  1   68.88  ? 394 LEU D O   1 
ATOM   1801 C CB  . LEU A 1 224 ? -52.935 -26.911 28.149  1   64.77  ? 394 LEU D CB  1 
ATOM   1802 C CG  . LEU A 1 224 ? -53.022 -25.917 29.309  1   62.75  ? 394 LEU D CG  1 
ATOM   1803 C CD1 . LEU A 1 224 ? -51.746 -25.921 30.127  1   60.04  ? 394 LEU D CD1 1 
ATOM   1804 C CD2 . LEU A 1 224 ? -53.296 -24.534 28.762  1   60.46  ? 394 LEU D CD2 1 
ATOM   1805 N N   . HIS A 1 225 ? -54.079 -29.886 28.254  1   75.49  ? 395 HIS D N   1 
ATOM   1806 C CA  . HIS A 1 225 ? -55.014 -30.917 28.766  1   77.69  ? 395 HIS D CA  1 
ATOM   1807 C C   . HIS A 1 225 ? -54.185 -31.991 29.461  1   79.23  ? 395 HIS D C   1 
ATOM   1808 O O   . HIS A 1 225 ? -54.515 -32.373 30.589  1   82.22  ? 395 HIS D O   1 
ATOM   1809 C CB  . HIS A 1 225 ? -55.857 -31.485 27.623  1   81.18  ? 395 HIS D CB  1 
ATOM   1810 C CG  . HIS A 1 225 ? -57.102 -32.175 28.066  1   83.61  ? 395 HIS D CG  1 
ATOM   1811 N ND1 . HIS A 1 225 ? -57.598 -32.073 29.346  1   83.17  ? 395 HIS D ND1 1 
ATOM   1812 C CD2 . HIS A 1 225 ? -57.949 -32.968 27.404  1   84.45  ? 395 HIS D CD2 1 
ATOM   1813 C CE1 . HIS A 1 225 ? -58.708 -32.786 29.44   1   84.51  ? 395 HIS D CE1 1 
ATOM   1814 N NE2 . HIS A 1 225 ? -58.939 -33.338 28.273  1   86.32  ? 395 HIS D NE2 1 
ATOM   1815 N N   . GLN A 1 226 ? -53.119 -32.436 28.8    1   79.13  ? 396 GLN D N   1 
ATOM   1816 C CA  . GLN A 1 226 ? -52.281 -33.476 29.387  1   83.61  ? 396 GLN D CA  1 
ATOM   1817 C C   . GLN A 1 226 ? -51.806 -32.997 30.755  1   82.52  ? 396 GLN D C   1 
ATOM   1818 O O   . GLN A 1 226 ? -51.997 -33.682 31.76   1   86.98  ? 396 GLN D O   1 
ATOM   1819 C CB  . GLN A 1 226 ? -51.049 -33.875 28.563  1   87.6   ? 396 GLN D CB  1 
ATOM   1820 C CG  . GLN A 1 226 ? -51.29  -34.877 27.437  1   97.21  ? 396 GLN D CG  1 
ATOM   1821 C CD  . GLN A 1 226 ? -52.116 -36.086 27.849  1   113.68 ? 396 GLN D CD  1 
ATOM   1822 O OE1 . GLN A 1 226 ? -53.197 -36.351 27.309  1   115.72 ? 396 GLN D OE1 1 
ATOM   1823 N NE2 . GLN A 1 226 ? -51.627 -36.842 28.822  1   118.7  ? 396 GLN D NE2 1 
ATOM   1824 N N   . THR A 1 227 ? -51.224 -31.792 30.764  1   76.1   ? 397 THR D N   1 
ATOM   1825 C CA  . THR A 1 227 ? -50.624 -31.212 31.953  1   74.17  ? 397 THR D CA  1 
ATOM   1826 C C   . THR A 1 227 ? -51.671 -31.125 33.068  1   75.39  ? 397 THR D C   1 
ATOM   1827 O O   . THR A 1 227 ? -51.383 -31.501 34.211  1   74.93  ? 397 THR D O   1 
ATOM   1828 C CB  . THR A 1 227 ? -49.989 -29.861 31.597  1   68.64  ? 397 THR D CB  1 
ATOM   1829 O OG1 . THR A 1 227 ? -49.064 -30.103 30.54   1   66.62  ? 397 THR D OG1 1 
ATOM   1830 C CG2 . THR A 1 227 ? -49.263 -29.211 32.76   1   64.77  ? 397 THR D CG2 1 
ATOM   1831 N N   . TYR A 1 228 ? -52.881 -30.651 32.719  1   74.39  ? 398 TYR D N   1 
ATOM   1832 C CA  . TYR A 1 228 ? -53.969 -30.49  33.675  1   76.79  ? 398 TYR D CA  1 
ATOM   1833 C C   . TYR A 1 228 ? -54.3   -31.845 34.298  1   81.55  ? 398 TYR D C   1 
ATOM   1834 O O   . TYR A 1 228 ? -54.485 -31.928 35.514  1   82.9   ? 398 TYR D O   1 
ATOM   1835 C CB  . TYR A 1 228 ? -55.186 -29.835 33.007  1   76.2   ? 398 TYR D CB  1 
ATOM   1836 C CG  . TYR A 1 228 ? -56.341 -29.434 33.92   1   76.8   ? 398 TYR D CG  1 
ATOM   1837 C CD1 . TYR A 1 228 ? -56.217 -29.457 35.311  1   77.57  ? 398 TYR D CD1 1 
ATOM   1838 C CD2 . TYR A 1 228 ? -57.558 -28.997 33.392  1   76.88  ? 398 TYR D CD2 1 
ATOM   1839 C CE1 . TYR A 1 228 ? -57.279 -29.108 36.135  1   77.81  ? 398 TYR D CE1 1 
ATOM   1840 C CE2 . TYR A 1 228 ? -58.621 -28.629 34.209  1   78.38  ? 398 TYR D CE2 1 
ATOM   1841 C CZ  . TYR A 1 228 ? -58.477 -28.68  35.588  1   78.92  ? 398 TYR D CZ  1 
ATOM   1842 O OH  . TYR A 1 228 ? -59.488 -28.337 36.448  1   81.21  ? 398 TYR D OH  1 
ATOM   1843 N N   . LEU A 1 229 ? -54.373 -32.88  33.442  1   85.16  ? 399 LEU D N   1 
ATOM   1844 C CA  . LEU A 1 229 ? -54.729 -34.247 33.811  1   88.72  ? 399 LEU D CA  1 
ATOM   1845 C C   . LEU A 1 229 ? -53.691 -34.837 34.761  1   89.18  ? 399 LEU D C   1 
ATOM   1846 O O   . LEU A 1 229 ? -54.049 -35.493 35.739  1   89.75  ? 399 LEU D O   1 
ATOM   1847 C CB  . LEU A 1 229 ? -54.871 -35.122 32.566  1   88.01  ? 399 LEU D CB  1 
ATOM   1848 C CG  . LEU A 1 229 ? -56.206 -35.046 31.822  1   86.84  ? 399 LEU D CG  1 
ATOM   1849 C CD1 . LEU A 1 229 ? -56.112 -35.781 30.491  1   86     ? 399 LEU D CD1 1 
ATOM   1850 C CD2 . LEU A 1 229 ? -57.312 -35.612 32.684  1   88.92  ? 399 LEU D CD2 1 
ATOM   1851 N N   . ARG A 1 230 ? -52.411 -34.589 34.456  1   88.56  ? 400 ARG D N   1 
ATOM   1852 C CA  . ARG A 1 230 ? -51.295 -35.193 35.17   1   90.13  ? 400 ARG D CA  1 
ATOM   1853 C C   . ARG A 1 230 ? -50.885 -34.347 36.374  1   85.17  ? 400 ARG D C   1 
ATOM   1854 O O   . ARG A 1 230 ? -50.002 -34.759 37.117  1   85.09  ? 400 ARG D O   1 
ATOM   1855 C CB  . ARG A 1 230 ? -50.084 -35.387 34.245  1   92.4   ? 400 ARG D CB  1 
ATOM   1856 C CG  . ARG A 1 230 ? -50.329 -36.387 33.125  1   100.74 ? 400 ARG D CG  1 
ATOM   1857 C CD  . ARG A 1 230 ? -49.189 -36.506 32.127  1   106.56 ? 400 ARG D CD  1 
ATOM   1858 N NE  . ARG A 1 230 ? -49.354 -37.71  31.296  1   113.18 ? 400 ARG D NE  1 
ATOM   1859 C CZ  . ARG A 1 230 ? -49.148 -37.827 29.981  1   112.34 ? 400 ARG D CZ  1 
ATOM   1860 N NH1 . ARG A 1 230 ? -48.742 -36.783 29.264  1   108.68 ? 400 ARG D NH1 1 
ATOM   1861 N NH2 . ARG A 1 230 ? -49.348 -38.996 29.391  1   107.73 ? 400 ARG D NH2 1 
ATOM   1862 N N   . ALA A 1 231 ? -51.473 -33.157 36.499  1   83.06  ? 401 ALA D N   1 
ATOM   1863 C CA  . ALA A 1 231 ? -51.058 -32.191 37.548  1   78.96  ? 401 ALA D CA  1 
ATOM   1864 C C   . ALA A 1 231 ? -50.898 -32.83  38.925  1   77.72  ? 401 ALA D C   1 
ATOM   1865 O O   . ALA A 1 231 ? -49.829 -32.638 39.517  1   74.24  ? 401 ALA D O   1 
ATOM   1866 C CB  . ALA A 1 231 ? -52.015 -31.021 37.577  1   76.94  ? 401 ALA D CB  1 
ATOM   1867 N N   . PRO A 1 232 ? -51.886 -33.558 39.487  1   82.24  ? 402 PRO D N   1 
ATOM   1868 C CA  . PRO A 1 232 ? -51.731 -34.094 40.829  1   83.69  ? 402 PRO D CA  1 
ATOM   1869 C C   . PRO A 1 232 ? -50.567 -35.058 40.936  1   83.06  ? 402 PRO D C   1 
ATOM   1870 O O   . PRO A 1 232 ? -50.213 -35.439 42.06   1   82.98  ? 402 PRO D O   1 
ATOM   1871 C CB  . PRO A 1 232 ? -53.081 -34.78  41.027  1   84.97  ? 402 PRO D CB  1 
ATOM   1872 C CG  . PRO A 1 232 ? -54.023 -34.012 40.143  1   83.03  ? 402 PRO D CG  1 
ATOM   1873 C CD  . PRO A 1 232 ? -53.183 -33.873 38.9    1   81.65  ? 402 PRO D CD  1 
ATOM   1874 N N   . GLN A 1 233 ? -49.967 -35.413 39.8    1   82.89  ? 403 GLN D N   1 
ATOM   1875 C CA  . GLN A 1 233 ? -48.865 -36.404 39.778  1   83.95  ? 403 GLN D CA  1 
ATOM   1876 C C   . GLN A 1 233 ? -47.528 -35.718 39.468  1   77.78  ? 403 GLN D C   1 
ATOM   1877 O O   . GLN A 1 233 ? -46.502 -36.422 39.456  1   77.05  ? 403 GLN D O   1 
ATOM   1878 C CB  . GLN A 1 233 ? -49.232 -37.444 38.721  1   88.27  ? 403 GLN D CB  1 
ATOM   1879 C CG  . GLN A 1 233 ? -49.847 -38.718 39.289  1   93.57  ? 403 GLN D CG  1 
ATOM   1880 C CD  . GLN A 1 233 ? -51.249 -38.519 39.819  1   97.24  ? 403 GLN D CD  1 
ATOM   1881 O OE1 . GLN A 1 233 ? -51.535 -38.772 40.994  1   102.19 ? 403 GLN D OE1 1 
ATOM   1882 N NE2 . GLN A 1 233 ? -52.139 -38.057 38.954  1   96.3   ? 403 GLN D NE2 1 
ATOM   1883 N N   . HIS A 1 234 ? -47.541 -34.402 39.249  1   72.56  ? 404 HIS D N   1 
ATOM   1884 C CA  . HIS A 1 234 ? -46.295 -33.648 38.946  1   69.24  ? 404 HIS D CA  1 
ATOM   1885 C C   . HIS A 1 234 ? -45.401 -33.586 40.188  1   67.08  ? 404 HIS D C   1 
ATOM   1886 O O   . HIS A 1 234 ? -45.899 -33.489 41.305  1   65.34  ? 404 HIS D O   1 
ATOM   1887 C CB  . HIS A 1 234 ? -46.635 -32.266 38.38   1   67.86  ? 404 HIS D CB  1 
ATOM   1888 C CG  . HIS A 1 234 ? -45.553 -31.644 37.563  1   68.63  ? 404 HIS D CG  1 
ATOM   1889 N ND1 . HIS A 1 234 ? -44.305 -31.345 38.061  1   67.54  ? 404 HIS D ND1 1 
ATOM   1890 C CD2 . HIS A 1 234 ? -45.54  -31.261 36.285  1   66.75  ? 404 HIS D CD2 1 
ATOM   1891 C CE1 . HIS A 1 234 ? -43.57  -30.805 37.105  1   66.36  ? 404 HIS D CE1 1 
ATOM   1892 N NE2 . HIS A 1 234 ? -44.301 -30.745 36.018  1   68.1   ? 404 HIS D NE2 1 
ATOM   1893 N N   . ALA A 1 235 ? -44.089 -33.671 39.986  1   66.41  ? 405 ALA D N   1 
ATOM   1894 C CA  . ALA A 1 235 ? -43.143 -33.561 41.117  1   65.85  ? 405 ALA D CA  1 
ATOM   1895 C C   . ALA A 1 235 ? -43.332 -32.203 41.767  1   65.81  ? 405 ALA D C   1 
ATOM   1896 O O   . ALA A 1 235 ? -43.204 -32.102 42.996  1   68.44  ? 405 ALA D O   1 
ATOM   1897 C CB  . ALA A 1 235 ? -41.74  -33.718 40.616  1   64.09  ? 405 ALA D CB  1 
ATOM   1898 N N   . GLN A 1 236 ? -43.627 -31.197 40.95   1   63.49  ? 406 GLN D N   1 
ATOM   1899 C CA  . GLN A 1 236 ? -43.856 -29.847 41.464  1   66.38  ? 406 GLN D CA  1 
ATOM   1900 C C   . GLN A 1 236 ? -45.344 -29.552 41.699  1   68.61  ? 406 GLN D C   1 
ATOM   1901 O O   . GLN A 1 236 ? -46.166 -29.678 40.785  1   68.14  ? 406 GLN D O   1 
ATOM   1902 C CB  . GLN A 1 236 ? -43.27  -28.798 40.519  1   64.78  ? 406 GLN D CB  1 
ATOM   1903 C CG  . GLN A 1 236 ? -41.785 -28.55  40.743  1   63.64  ? 406 GLN D CG  1 
ATOM   1904 C CD  . GLN A 1 236 ? -40.9   -29.723 40.382  1   67.69  ? 406 GLN D CD  1 
ATOM   1905 O OE1 . GLN A 1 236 ? -40.951 -30.264 39.264  1   72.79  ? 406 GLN D OE1 1 
ATOM   1906 N NE2 . GLN A 1 236 ? -40.076 -30.119 41.342  1   66.25  ? 406 GLN D NE2 1 
ATOM   1907 N N   . GLN A 1 237 ? -45.653 -29.08  42.92   1   69.71  ? 407 GLN D N   1 
ATOM   1908 C CA  . GLN A 1 237 ? -47.009 -29.022 43.446  1   74.04  ? 407 GLN D CA  1 
ATOM   1909 C C   . GLN A 1 237 ? -47.396 -27.623 43.923  1   76.25  ? 407 GLN D C   1 
ATOM   1910 O O   . GLN A 1 237 ? -48.58  -27.398 44.194  1   86.35  ? 407 GLN D O   1 
ATOM   1911 C CB  . GLN A 1 237 ? -47.157 -29.941 44.658  1   74.77  ? 407 GLN D CB  1 
ATOM   1912 C CG  . GLN A 1 237 ? -47.197 -31.421 44.309  1   77.89  ? 407 GLN D CG  1 
ATOM   1913 C CD  . GLN A 1 237 ? -48.208 -31.736 43.229  1   81.2   ? 407 GLN D CD  1 
ATOM   1914 O OE1 . GLN A 1 237 ? -49.399 -31.408 43.319  1   83.51  ? 407 GLN D OE1 1 
ATOM   1915 N NE2 . GLN A 1 237 ? -47.739 -32.401 42.19   1   81.56  ? 407 GLN D NE2 1 
ATOM   1916 N N   . SER A 1 238 ? -46.422 -26.71  44.046  1   69.96  ? 408 SER D N   1 
ATOM   1917 C CA  . SER A 1 238 ? -46.655 -25.434 44.712  1   70.34  ? 408 SER D CA  1 
ATOM   1918 C C   . SER A 1 238 ? -47.829 -24.678 44.077  1   69.66  ? 408 SER D C   1 
ATOM   1919 O O   . SER A 1 238 ? -48.511 -23.898 44.75   1   69.43  ? 408 SER D O   1 
ATOM   1920 C CB  . SER A 1 238 ? -45.398 -24.58  44.752  1   65.77  ? 408 SER D CB  1 
ATOM   1921 O OG  . SER A 1 238 ? -44.32  -25.295 45.332  1   62.44  ? 408 SER D OG  1 
ATOM   1922 N N   . ILE A 1 239 ? -48.067 -24.926 42.784  1   67.01  ? 409 ILE D N   1 
ATOM   1923 C CA  . ILE A 1 239 ? -49.112 -24.21  42.081  1   64.62  ? 409 ILE D CA  1 
ATOM   1924 C C   . ILE A 1 239 ? -50.466 -24.807 42.45   1   71.33  ? 409 ILE D C   1 
ATOM   1925 O O   . ILE A 1 239 ? -51.431 -24.073 42.675  1   74.76  ? 409 ILE D O   1 
ATOM   1926 C CB  . ILE A 1 239 ? -48.842 -24.161 40.573  1   61.2   ? 409 ILE D CB  1 
ATOM   1927 C CG1 . ILE A 1 239 ? -47.458 -23.525 40.303  1   60.17  ? 409 ILE D CG1 1 
ATOM   1928 C CG2 . ILE A 1 239 ? -49.949 -23.375 39.883  1   59.12  ? 409 ILE D CG2 1 
ATOM   1929 C CD1 . ILE A 1 239 ? -47.015 -23.458 38.849  1   56.59  ? 409 ILE D CD1 1 
ATOM   1930 N N   . ARG A 1 240 ? -50.515 -26.137 42.575  1   75.08  ? 410 ARG D N   1 
ATOM   1931 C CA  . ARG A 1 240 ? -51.748 -26.804 42.968  1   74.9   ? 410 ARG D CA  1 
ATOM   1932 C C   . ARG A 1 240 ? -52.142 -26.388 44.383  1   77.54  ? 410 ARG D C   1 
ATOM   1933 O O   . ARG A 1 240 ? -53.309 -26.075 44.625  1   78.9   ? 410 ARG D O   1 
ATOM   1934 C CB  . ARG A 1 240 ? -51.631 -28.323 42.852  1   74.2   ? 410 ARG D CB  1 
ATOM   1935 C CG  . ARG A 1 240 ? -51.848 -28.851 41.443  1   72.11  ? 410 ARG D CG  1 
ATOM   1936 C CD  . ARG A 1 240 ? -52.001 -30.371 41.384  1   74.34  ? 410 ARG D CD  1 
ATOM   1937 N NE  . ARG A 1 240 ? -53.295 -30.869 41.878  1   74.64  ? 410 ARG D NE  1 
ATOM   1938 C CZ  . ARG A 1 240 ? -53.459 -31.563 42.998  1   74.99  ? 410 ARG D CZ  1 
ATOM   1939 N NH1 . ARG A 1 240 ? -54.647 -32.04  43.316  1   76.3   ? 410 ARG D NH1 1 
ATOM   1940 N NH2 . ARG A 1 240 ? -52.437 -31.804 43.792  1   73.89  ? 410 ARG D NH2 1 
ATOM   1941 N N   . GLU A 1 241 ? -51.161 -26.382 45.295  1   79.41  ? 411 GLU D N   1 
ATOM   1942 C CA  . GLU A 1 241 ? -51.362 -25.914 46.662  1   82.34  ? 411 GLU D CA  1 
ATOM   1943 C C   . GLU A 1 241 ? -51.872 -24.474 46.66   1   81.7   ? 411 GLU D C   1 
ATOM   1944 O O   . GLU A 1 241 ? -52.841 -24.156 47.355  1   84.64  ? 411 GLU D O   1 
ATOM   1945 C CB  . GLU A 1 241 ? -50.076 -25.958 47.489  1   81.41  ? 411 GLU D CB  1 
ATOM   1946 C CG  . GLU A 1 241 ? -49.655 -27.369 47.886  1   88.64  ? 411 GLU D CG  1 
ATOM   1947 C CD  . GLU A 1 241 ? -50.813 -28.219 48.392  1   98.64  ? 411 GLU D CD  1 
ATOM   1948 O OE1 . GLU A 1 241 ? -51.583 -27.739 49.263  1   102.87 ? 411 GLU D OE1 1 
ATOM   1949 O OE2 . GLU A 1 241 ? -50.942 -29.372 47.916  1   99.36  ? 411 GLU D OE2 1 
ATOM   1950 N N   . LYS A 1 242 ? -51.208 -23.623 45.863  1   75.7   ? 412 LYS D N   1 
ATOM   1951 C CA  . LYS A 1 242 ? -51.509 -22.203 45.834  1   70.52  ? 412 LYS D CA  1 
ATOM   1952 C C   . LYS A 1 242 ? -52.979 -22.007 45.459  1   72.83  ? 412 LYS D C   1 
ATOM   1953 O O   . LYS A 1 242 ? -53.663 -21.166 46.045  1   73.28  ? 412 LYS D O   1 
ATOM   1954 C CB  . LYS A 1 242 ? -50.547 -21.498 44.87   1   64.17  ? 412 LYS D CB  1 
ATOM   1955 C CG  . LYS A 1 242 ? -50.869 -20.054 44.527  1   59.37  ? 412 LYS D CG  1 
ATOM   1956 C CD  . LYS A 1 242 ? -49.799 -19.41  43.664  1   54.77  ? 412 LYS D CD  1 
ATOM   1957 C CE  . LYS A 1 242 ? -50.155 -18.094 43.049  1   51.96  ? 412 LYS D CE  1 
ATOM   1958 N NZ  . LYS A 1 242 ? -49.164 -17.63  42.075  1   49.47  ? 412 LYS D NZ  1 
ATOM   1959 N N   . TYR A 1 243 ? -53.452 -22.799 44.488  1   71.77  ? 413 TYR D N   1 
ATOM   1960 C CA  . TYR A 1 243 ? -54.754 -22.58  43.877  1   73.24  ? 413 TYR D CA  1 
ATOM   1961 C C   . TYR A 1 243 ? -55.826 -23.459 44.535  1   76.69  ? 413 TYR D C   1 
ATOM   1962 O O   . TYR A 1 243 ? -56.896 -23.644 43.967  1   77.58  ? 413 TYR D O   1 
ATOM   1963 C CB  . TYR A 1 243 ? -54.664 -22.733 42.354  1   69.61  ? 413 TYR D CB  1 
ATOM   1964 C CG  . TYR A 1 243 ? -54.166 -21.516 41.588  1   67.7   ? 413 TYR D CG  1 
ATOM   1965 C CD1 . TYR A 1 243 ? -52.807 -21.183 41.544  1   68.46  ? 413 TYR D CD1 1 
ATOM   1966 C CD2 . TYR A 1 243 ? -55.051 -20.702 40.891  1   67.41  ? 413 TYR D CD2 1 
ATOM   1967 C CE1 . TYR A 1 243 ? -52.339 -20.088 40.827  1   62.7   ? 413 TYR D CE1 1 
ATOM   1968 C CE2 . TYR A 1 243 ? -54.603 -19.6   40.175  1   64.99  ? 413 TYR D CE2 1 
ATOM   1969 C CZ  . TYR A 1 243 ? -53.248 -19.302 40.141  1   63.99  ? 413 TYR D CZ  1 
ATOM   1970 O OH  . TYR A 1 243 ? -52.841 -18.215 39.443  1   63.28  ? 413 TYR D OH  1 
ATOM   1971 N N   . LYS A 1 244 ? -55.547 -23.961 45.743  1   78.02  ? 414 LYS D N   1 
ATOM   1972 C CA  . LYS A 1 244 ? -56.553 -24.583 46.589  1   83.6   ? 414 LYS D CA  1 
ATOM   1973 C C   . LYS A 1 244 ? -57.314 -23.535 47.399  1   85.04  ? 414 LYS D C   1 
ATOM   1974 O O   . LYS A 1 244 ? -58.483 -23.747 47.735  1   86.58  ? 414 LYS D O   1 
ATOM   1975 C CB  . LYS A 1 244 ? -55.905 -25.57  47.565  1   85.46  ? 414 LYS D CB  1 
ATOM   1976 C CG  . LYS A 1 244 ? -55.474 -26.878 46.925  1   87.86  ? 414 LYS D CG  1 
ATOM   1977 C CD  . LYS A 1 244 ? -54.768 -27.813 47.898  1   90.79  ? 414 LYS D CD  1 
ATOM   1978 C CE  . LYS A 1 244 ? -54.395 -29.134 47.29   1   91.26  ? 414 LYS D CE  1 
ATOM   1979 N NZ  . LYS A 1 244 ? -53.882 -30.04  48.324  1   93.66  ? 414 LYS D NZ  1 
ATOM   1980 N N   . ASN A 1 245 ? -56.651 -22.415 47.712  1   82.31  ? 415 ASN D N   1 
ATOM   1981 C CA  . ASN A 1 245 ? -57.18  -21.462 48.676  1   90.2   ? 415 ASN D CA  1 
ATOM   1982 C C   . ASN A 1 245 ? -58.406 -20.768 48.105  1   92.88  ? 415 ASN D C   1 
ATOM   1983 O O   . ASN A 1 245 ? -58.549 -20.652 46.88   1   91.75  ? 415 ASN D O   1 
ATOM   1984 C CB  . ASN A 1 245 ? -56.16  -20.419 49.119  1   92.27  ? 415 ASN D CB  1 
ATOM   1985 C CG  . ASN A 1 245 ? -54.866 -21.075 49.531  1   100.39 ? 415 ASN D CG  1 
ATOM   1986 O OD1 . ASN A 1 245 ? -54.885 -22.084 50.244  1   107.12 ? 415 ASN D OD1 1 
ATOM   1987 N ND2 . ASN A 1 245 ? -53.74  -20.565 49.053  1   105.47 ? 415 ASN D ND2 1 
ATOM   1988 N N   . SER A 1 246 ? -59.257 -20.297 49.032  1   92.51  ? 416 SER D N   1 
ATOM   1989 C CA  . SER A 1 246 ? -60.464 -19.583 48.658  1   93.16  ? 416 SER D CA  1 
ATOM   1990 C C   . SER A 1 246 ? -60.099 -18.381 47.787  1   90.88  ? 416 SER D C   1 
ATOM   1991 O O   . SER A 1 246 ? -60.832 -18.07  46.846  1   89.24  ? 416 SER D O   1 
ATOM   1992 C CB  . SER A 1 246 ? -61.302 -19.194 49.857  1   93.16  ? 416 SER D CB  1 
ATOM   1993 O OG  . SER A 1 246 ? -60.991 -17.882 50.3    1   92.01  ? 416 SER D OG  1 
ATOM   1994 N N   . LYS A 1 247 ? -58.955 -17.744 48.103  1   88.61  ? 417 LYS D N   1 
ATOM   1995 C CA  . LYS A 1 247 ? -58.41  -16.647 47.321  1   86.91  ? 417 LYS D CA  1 
ATOM   1996 C C   . LYS A 1 247 ? -58.61  -16.902 45.822  1   89.11  ? 417 LYS D C   1 
ATOM   1997 O O   . LYS A 1 247 ? -59.082 -16.005 45.125  1   88.49  ? 417 LYS D O   1 
ATOM   1998 C CB  . LYS A 1 247 ? -56.954 -16.403 47.735  1   86.1   ? 417 LYS D CB  1 
ATOM   1999 C CG  . LYS A 1 247 ? -56.174 -15.463 46.827  1   85.61  ? 417 LYS D CG  1 
ATOM   2000 C CD  . LYS A 1 247 ? -54.681 -15.43  47.136  1   93.57  ? 417 LYS D CD  1 
ATOM   2001 C CE  . LYS A 1 247 ? -54.162 -14.327 48.011  1   97.54  ? 417 LYS D CE  1 
ATOM   2002 N NZ  . LYS A 1 247 ? -53.6   -13.249 47.191  1   90.05  ? 417 LYS D NZ  1 
ATOM   2003 N N   . TYR A 1 248 ? -58.293 -18.125 45.346  1   88.66  ? 418 TYR D N   1 
ATOM   2004 C CA  . TYR A 1 248 ? -58.452 -18.507 43.943  1   89.29  ? 418 TYR D CA  1 
ATOM   2005 C C   . TYR A 1 248 ? -59.632 -19.464 43.735  1   92.25  ? 418 TYR D C   1 
ATOM   2006 O O   . TYR A 1 248 ? -59.637 -20.239 42.776  1   90.37  ? 418 TYR D O   1 
ATOM   2007 C CB  . TYR A 1 248 ? -57.189 -19.151 43.357  1   82.84  ? 418 TYR D CB  1 
ATOM   2008 C CG  . TYR A 1 248 ? -55.953 -18.287 43.511  1   78.3   ? 418 TYR D CG  1 
ATOM   2009 C CD1 . TYR A 1 248 ? -55.745 -17.187 42.679  1   76.95  ? 418 TYR D CD1 1 
ATOM   2010 C CD2 . TYR A 1 248 ? -55.015 -18.562 44.508  1   77.54  ? 418 TYR D CD2 1 
ATOM   2011 C CE1 . TYR A 1 248 ? -54.625 -16.379 42.842  1   75.65  ? 418 TYR D CE1 1 
ATOM   2012 C CE2 . TYR A 1 248 ? -53.911 -17.744 44.694  1   75.8   ? 418 TYR D CE2 1 
ATOM   2013 C CZ  . TYR A 1 248 ? -53.718 -16.645 43.863  1   77.11  ? 418 TYR D CZ  1 
ATOM   2014 O OH  . TYR A 1 248 ? -52.611 -15.846 44.046  1   78.14  ? 418 TYR D OH  1 
ATOM   2015 N N   . HIS A 1 249 ? -60.63  -19.415 44.625  1   93.16  ? 419 HIS D N   1 
ATOM   2016 C CA  . HIS A 1 249 ? -61.87  -20.152 44.427  1   98.47  ? 419 HIS D CA  1 
ATOM   2017 C C   . HIS A 1 249 ? -61.631 -21.663 44.436  1   96.38  ? 419 HIS D C   1 
ATOM   2018 O O   . HIS A 1 249 ? -62.503 -22.416 44.016  1   94.7   ? 419 HIS D O   1 
ATOM   2019 C CB  . HIS A 1 249 ? -62.617 -19.661 43.175  1   103.05 ? 419 HIS D CB  1 
ATOM   2020 C CG  . HIS A 1 249 ? -62.992 -18.215 43.26   1   112.25 ? 419 HIS D CG  1 
ATOM   2021 N ND1 . HIS A 1 249 ? -62.202 -17.181 42.793  1   111.02 ? 419 HIS D ND1 1 
ATOM   2022 C CD2 . HIS A 1 249 ? -64.077 -17.637 43.8    1   115.4  ? 419 HIS D CD2 1 
ATOM   2023 C CE1 . HIS A 1 249 ? -62.809 -16.022 43.024  1   109.28 ? 419 HIS D CE1 1 
ATOM   2024 N NE2 . HIS A 1 249 ? -63.943 -16.276 43.645  1   117.15 ? 419 HIS D NE2 1 
ATOM   2025 N N   . GLY A 1 250 ? -60.451 -22.09  44.908  1   94.69  ? 420 GLY D N   1 
ATOM   2026 C CA  . GLY A 1 250 ? -60.086 -23.497 45.014  1   90.51  ? 420 GLY D CA  1 
ATOM   2027 C C   . GLY A 1 250 ? -60.131 -24.246 43.681  1   87.31  ? 420 GLY D C   1 
ATOM   2028 O O   . GLY A 1 250 ? -60.357 -25.456 43.669  1   94.51  ? 420 GLY D O   1 
ATOM   2029 N N   . VAL A 1 251 ? -59.879 -23.546 42.572  1   79.52  ? 421 VAL D N   1 
ATOM   2030 C CA  . VAL A 1 251 ? -60.07  -24.116 41.248  1   79.26  ? 421 VAL D CA  1 
ATOM   2031 C C   . VAL A 1 251 ? -59.186 -25.344 41.014  1   79.65  ? 421 VAL D C   1 
ATOM   2032 O O   . VAL A 1 251 ? -59.559 -26.236 40.247  1   81.2   ? 421 VAL D O   1 
ATOM   2033 C CB  . VAL A 1 251 ? -59.944 -23.105 40.097  1   76.5   ? 421 VAL D CB  1 
ATOM   2034 C CG1 . VAL A 1 251 ? -61.103 -22.112 40.084  1   76.56  ? 421 VAL D CG1 1 
ATOM   2035 C CG2 . VAL A 1 251 ? -58.605 -22.392 40.12   1   72.66  ? 421 VAL D CG2 1 
ATOM   2036 N N   . SER A 1 252 ? -58.032 -25.407 41.692  1   78.62  ? 422 SER D N   1 
ATOM   2037 C CA  . SER A 1 252 ? -57.093 -26.511 41.51   1   79.61  ? 422 SER D CA  1 
ATOM   2038 C C   . SER A 1 252 ? -57.717 -27.852 41.897  1   83.18  ? 422 SER D C   1 
ATOM   2039 O O   . SER A 1 252 ? -57.255 -28.88  41.413  1   81.9   ? 422 SER D O   1 
ATOM   2040 C CB  . SER A 1 252 ? -55.789 -26.306 42.242  1   76.64  ? 422 SER D CB  1 
ATOM   2041 O OG  . SER A 1 252 ? -55.923 -26.592 43.627  1   79.41  ? 422 SER D OG  1 
ATOM   2042 N N   . LEU A 1 253 ? -58.742 -27.816 42.767  1   85.85  ? 423 LEU D N   1 
ATOM   2043 C CA  . LEU A 1 253 ? -59.393 -28.993 43.325  1   88.21  ? 423 LEU D CA  1 
ATOM   2044 C C   . LEU A 1 253 ? -60.461 -29.539 42.382  1   89.94  ? 423 LEU D C   1 
ATOM   2045 O O   . LEU A 1 253 ? -60.951 -30.646 42.588  1   92.95  ? 423 LEU D O   1 
ATOM   2046 C CB  . LEU A 1 253 ? -59.979 -28.656 44.697  1   89.56  ? 423 LEU D CB  1 
ATOM   2047 C CG  . LEU A 1 253 ? -58.996 -28.743 45.869  1   89     ? 423 LEU D CG  1 
ATOM   2048 C CD1 . LEU A 1 253 ? -59.444 -27.992 47.11   1   87.42  ? 423 LEU D CD1 1 
ATOM   2049 C CD2 . LEU A 1 253 ? -58.745 -30.204 46.189  1   89.45  ? 423 LEU D CD2 1 
ATOM   2050 N N   . LEU A 1 254 ? -60.827 -28.759 41.362  1   89.13  ? 424 LEU D N   1 
ATOM   2051 C CA  . LEU A 1 254 ? -61.791 -29.21  40.377  1   91.83  ? 424 LEU D CA  1 
ATOM   2052 C C   . LEU A 1 254 ? -61.203 -30.364 39.562  1   94.88  ? 424 LEU D C   1 
ATOM   2053 O O   . LEU A 1 254 ? -60.099 -30.264 39.026  1   93.99  ? 424 LEU D O   1 
ATOM   2054 C CB  . LEU A 1 254 ? -62.214 -28.032 39.502  1   88.79  ? 424 LEU D CB  1 
ATOM   2055 C CG  . LEU A 1 254 ? -62.957 -26.903 40.228  1   89.25  ? 424 LEU D CG  1 
ATOM   2056 C CD1 . LEU A 1 254 ? -63.236 -25.749 39.266  1   88.11  ? 424 LEU D CD1 1 
ATOM   2057 C CD2 . LEU A 1 254 ? -64.259 -27.377 40.896  1   90.34  ? 424 LEU D CD2 1 
ATOM   2058 N N   . ASN A 1 255 ? -61.947 -31.476 39.503  1   98.95  ? 425 ASN D N   1 
ATOM   2059 C CA  . ASN A 1 255 ? -61.592 -32.599 38.649  1   100.64 ? 425 ASN D CA  1 
ATOM   2060 C C   . ASN A 1 255 ? -61.547 -32.063 37.216  1   98.53  ? 425 ASN D C   1 
ATOM   2061 O O   . ASN A 1 255 ? -62.519 -31.46  36.757  1   99.65  ? 425 ASN D O   1 
ATOM   2062 C CB  . ASN A 1 255 ? -62.543 -33.788 38.822  1   103.55 ? 425 ASN D CB  1 
ATOM   2063 C CG  . ASN A 1 255 ? -62.759 -34.227 40.258  1   105.58 ? 425 ASN D CG  1 
ATOM   2064 O OD1 . ASN A 1 255 ? -62.301 -33.584 41.211  1   104.73 ? 425 ASN D OD1 1 
ATOM   2065 N ND2 . ASN A 1 255 ? -63.464 -35.332 40.443  1   109.9  ? 425 ASN D ND2 1 
ATOM   2066 N N   . PRO A 1 256 ? -60.425 -32.228 36.472  1   92.77  ? 426 PRO D N   1 
ATOM   2067 C CA  . PRO A 1 256 ? -60.388 -31.8   35.069  1   90.77  ? 426 PRO D CA  1 
ATOM   2068 C C   . PRO A 1 256 ? -61.373 -32.596 34.201  1   96.15  ? 426 PRO D C   1 
ATOM   2069 O O   . PRO A 1 256 ? -61.776 -33.709 34.551  1   97.44  ? 426 PRO D O   1 
ATOM   2070 C CB  . PRO A 1 256 ? -58.935 -32.067 34.679  1   88.32  ? 426 PRO D CB  1 
ATOM   2071 C CG  . PRO A 1 256 ? -58.483 -33.182 35.616  1   90.07  ? 426 PRO D CG  1 
ATOM   2072 C CD  . PRO A 1 256 ? -59.184 -32.88  36.925  1   90.48  ? 426 PRO D CD  1 
ATOM   2073 N N   . PRO A 1 257 ? -61.798 -32.073 33.028  1   96.44  ? 427 PRO D N   1 
ATOM   2074 C CA  . PRO A 1 257 ? -62.629 -32.841 32.093  1   100.11 ? 427 PRO D CA  1 
ATOM   2075 C C   . PRO A 1 257 ? -61.777 -33.957 31.488  1   103.51 ? 427 PRO D C   1 
ATOM   2076 O O   . PRO A 1 257 ? -60.545 -33.897 31.564  1   106.53 ? 427 PRO D O   1 
ATOM   2077 C CB  . PRO A 1 257 ? -63.026 -31.796 31.046  1   98.04  ? 427 PRO D CB  1 
ATOM   2078 C CG  . PRO A 1 257 ? -61.845 -30.855 31.036  1   93.9   ? 427 PRO D CG  1 
ATOM   2079 C CD  . PRO A 1 257 ? -61.425 -30.756 32.5    1   93.81  ? 427 PRO D CD  1 
ATOM   2080 N N   . GLU A 1 258 ? -62.437 -34.962 30.893  1   108.53 ? 428 GLU D N   1 
ATOM   2081 C CA  . GLU A 1 258 ? -61.744 -36.169 30.464  1   109.38 ? 428 GLU D CA  1 
ATOM   2082 C C   . GLU A 1 258 ? -61.375 -36.096 28.983  1   108.2  ? 428 GLU D C   1 
ATOM   2083 O O   . GLU A 1 258 ? -60.379 -36.693 28.578  1   103.48 ? 428 GLU D O   1 
ATOM   2084 C CB  . GLU A 1 258 ? -62.505 -37.431 30.868  1   116.42 ? 428 GLU D CB  1 
ATOM   2085 C CG  . GLU A 1 258 ? -61.872 -38.169 32.049  1   120.94 ? 428 GLU D CG  1 
ATOM   2086 C CD  . GLU A 1 258 ? -62.756 -39.255 32.653  1   130.27 ? 428 GLU D CD  1 
ATOM   2087 O OE1 . GLU A 1 258 ? -62.535 -40.444 32.34   1   135.19 ? 428 GLU D OE1 1 
ATOM   2088 O OE2 . GLU A 1 258 ? -63.665 -38.929 33.445  1   132.83 ? 428 GLU D OE2 1 
ATOM   2089 N N   . THR A 1 259 ? -62.191 -35.372 28.197  1   110.46 ? 429 THR D N   1 
ATOM   2090 C CA  . THR A 1 259 ? -61.968 -35.128 26.77   1   112.09 ? 429 THR D CA  1 
ATOM   2091 C C   . THR A 1 259 ? -62.44  -33.726 26.38   1   110.4  ? 429 THR D C   1 
ATOM   2092 O O   . THR A 1 259 ? -63.102 -33.046 27.166  1   109.38 ? 429 THR D O   1 
ATOM   2093 C CB  . THR A 1 259 ? -62.671 -36.159 25.882  1   118.63 ? 429 THR D CB  1 
ATOM   2094 O OG1 . THR A 1 259 ? -63.896 -36.484 26.536  1   123.22 ? 429 THR D OG1 1 
ATOM   2095 C CG2 . THR A 1 259 ? -61.828 -37.386 25.569  1   117.11 ? 429 THR D CG2 1 
ATOM   2096 N N   . LEU A 1 260 ? -62.095 -33.324 25.143  1   111.57 ? 430 LEU D N   1 
ATOM   2097 C CA  . LEU A 1 260 ? -62.611 -32.132 24.48   1   111.76 ? 430 LEU D CA  1 
ATOM   2098 C C   . LEU A 1 260 ? -63.461 -32.571 23.29   1   119.89 ? 430 LEU D C   1 
ATOM   2099 O O   . LEU A 1 260 ? -63.598 -33.771 23.036  1   120.41 ? 430 LEU D O   1 
ATOM   2100 C CB  . LEU A 1 260 ? -61.439 -31.265 24.028  1   104.43 ? 430 LEU D CB  1 
ATOM   2101 C CG  . LEU A 1 260 ? -60.333 -31.074 25.071  1   103.33 ? 430 LEU D CG  1 
ATOM   2102 C CD1 . LEU A 1 260 ? -59.037 -30.634 24.422  1   105.44 ? 430 LEU D CD1 1 
ATOM   2103 C CD2 . LEU A 1 260 ? -60.718 -30.108 26.182  1   100.02 ? 430 LEU D CD2 1 
ATOM   2104 N N   . ASN A 1 261 ? -64.035 -31.595 22.568  1   122.23 ? 431 ASN D N   1 
ATOM   2105 C CA  . ASN A 1 261 ? -64.788 -31.891 21.356  1   130.32 ? 431 ASN D CA  1 
ATOM   2106 C C   . ASN A 1 261 ? -63.92  -31.594 20.137  1   133.49 ? 431 ASN D C   1 
ATOM   2107 O O   . ASN A 1 261 ? -63.968 -30.492 19.597  1   132.9  ? 431 ASN D O   1 
ATOM   2108 C CB  . ASN A 1 261 ? -66.124 -31.153 21.296  1   130.09 ? 431 ASN D CB  1 
ATOM   2109 C CG  . ASN A 1 261 ? -67.131 -31.699 22.284  1   132.72 ? 431 ASN D CG  1 
ATOM   2110 O OD1 . ASN A 1 261 ? -67.674 -32.796 22.085  1   126.76 ? 431 ASN D OD1 1 
ATOM   2111 N ND2 . ASN A 1 261 ? -67.376 -30.953 23.356  1   135.42 ? 431 ASN D ND2 1 
ATOM   2112 N N   . VAL A 1 262 ? -63.132 -32.593 19.715  1   135.4  ? 432 VAL D N   1 
ATOM   2113 C CA  . VAL A 1 262 ? -62.212 -32.471 18.591  1   128.94 ? 432 VAL D CA  1 
ATOM   2114 C C   . VAL A 1 262 ? -62.31  -33.762 17.753  1   127.64 ? 432 VAL D C   1 
ATOM   2115 O O   . VAL A 1 262 ? -63.283 -33.903 16.97   1   123.7  ? 432 VAL D O   1 
ATOM   2116 C CB  . VAL A 1 262 ? -60.748 -32.171 19.002  1   121.98 ? 432 VAL D CB  1 
ATOM   2117 C CG1 . VAL A 1 262 ? -60.63  -31.009 19.993  1   116.08 ? 432 VAL D CG1 1 
ATOM   2118 C CG2 . VAL A 1 262 ? -60.002 -33.397 19.53   1   118.07 ? 432 VAL D CG2 1 
ATOM   2119 N N   . GLY B 2 1   ? -20.642 -7.423  23.766  1   95.32  ? -3  GLY A N   1 
ATOM   2120 C CA  . GLY B 2 1   ? -21.819 -6.708  24.305  1   92.4   ? -3  GLY A CA  1 
ATOM   2121 C C   . GLY B 2 1   ? -21.948 -6.874  25.82   1   93.65  ? -3  GLY A C   1 
ATOM   2122 O O   . GLY B 2 1   ? -21.557 -5.973  26.556  1   101.27 ? -3  GLY A O   1 
ATOM   2123 N N   . PRO B 2 2   ? -22.474 -8.024  26.323  1   92.92  ? -2  PRO A N   1 
ATOM   2124 C CA  . PRO B 2 2   ? -22.924 -8.156  27.72   1   93.81  ? -2  PRO A CA  1 
ATOM   2125 C C   . PRO B 2 2   ? -21.964 -8.029  28.909  1   93.73  ? -2  PRO A C   1 
ATOM   2126 O O   . PRO B 2 2   ? -22.372 -7.559  29.971  1   89.69  ? -2  PRO A O   1 
ATOM   2127 C CB  . PRO B 2 2   ? -23.62  -9.547  27.722  1   90.44  ? -2  PRO A CB  1 
ATOM   2128 C CG  . PRO B 2 2   ? -22.916 -10.332 26.645  1   90.07  ? -2  PRO A CG  1 
ATOM   2129 C CD  . PRO B 2 2   ? -22.657 -9.28   25.57   1   94.32  ? -2  PRO A CD  1 
ATOM   2130 N N   . GLY B 2 3   ? -20.708 -8.48   28.74   1   91.94  ? -1  GLY A N   1 
ATOM   2131 C CA  . GLY B 2 3   ? -19.809 -8.76   29.859  1   88.44  ? -1  GLY A CA  1 
ATOM   2132 C C   . GLY B 2 3   ? -18.816 -7.64   30.185  1   86.8   ? -1  GLY A C   1 
ATOM   2133 O O   . GLY B 2 3   ? -18.634 -6.693  29.424  1   84.75  ? -1  GLY A O   1 
ATOM   2134 N N   . SER B 2 4   ? -18.152 -7.804  31.335  1   90.61  ? 0   SER A N   1 
ATOM   2135 C CA  . SER B 2 4   ? -17.22  -6.866  31.954  1   92.85  ? 0   SER A CA  1 
ATOM   2136 C C   . SER B 2 4   ? -16.118 -7.661  32.675  1   91.84  ? 0   SER A C   1 
ATOM   2137 O O   . SER B 2 4   ? -16.391 -8.719  33.257  1   93.01  ? 0   SER A O   1 
ATOM   2138 C CB  . SER B 2 4   ? -17.974 -5.949  32.899  1   92.37  ? 0   SER A CB  1 
ATOM   2139 O OG  . SER B 2 4   ? -17.12  -5.366  33.876  1   98.62  ? 0   SER A OG  1 
ATOM   2140 N N   . MET B 2 5   ? -14.866 -7.169  32.641  1   86.91  ? 1   MET A N   1 
ATOM   2141 C CA  . MET B 2 5   ? -13.743 -7.948  33.159  1   79.67  ? 1   MET A CA  1 
ATOM   2142 C C   . MET B 2 5   ? -13.856 -8.172  34.662  1   77.71  ? 1   MET A C   1 
ATOM   2143 O O   . MET B 2 5   ? -13.264 -9.117  35.159  1   78.13  ? 1   MET A O   1 
ATOM   2144 C CB  . MET B 2 5   ? -12.381 -7.327  32.851  1   77.26  ? 1   MET A CB  1 
ATOM   2145 C CG  . MET B 2 5   ? -12.097 -7.274  31.375  1   74.62  ? 1   MET A CG  1 
ATOM   2146 S SD  . MET B 2 5   ? -12.189 -8.903  30.614  1   74.54  ? 1   MET A SD  1 
ATOM   2147 C CE  . MET B 2 5   ? -10.955 -9.774  31.581  1   75.58  ? 1   MET A CE  1 
ATOM   2148 N N   . GLU B 2 6   ? -14.637 -7.344  35.366  1   77.36  ? 2   GLU A N   1 
ATOM   2149 C CA  . GLU B 2 6   ? -14.783 -7.49   36.805  1   78.56  ? 2   GLU A CA  1 
ATOM   2150 C C   . GLU B 2 6   ? -15.377 -8.855  37.174  1   74.61  ? 2   GLU A C   1 
ATOM   2151 O O   . GLU B 2 6   ? -15.119 -9.374  38.254  1   75.52  ? 2   GLU A O   1 
ATOM   2152 C CB  . GLU B 2 6   ? -15.585 -6.343  37.412  1   84.14  ? 2   GLU A CB  1 
ATOM   2153 C CG  . GLU B 2 6   ? -15.697 -6.425  38.935  1   97.9   ? 2   GLU A CG  1 
ATOM   2154 C CD  . GLU B 2 6   ? -14.495 -6.301  39.877  1   105.79 ? 2   GLU A CD  1 
ATOM   2155 O OE1 . GLU B 2 6   ? -13.4   -5.883  39.429  1   108.59 ? 2   GLU A OE1 1 
ATOM   2156 O OE2 . GLU B 2 6   ? -14.633 -6.66   41.069  1   109.71 ? 2   GLU A OE2 1 
ATOM   2157 N N   . ASN B 2 7   ? -16.161 -9.452  36.272  1   71.26  ? 3   ASN A N   1 
ATOM   2158 C CA  . ASN B 2 7   ? -16.857 -10.704 36.548  1   70.01  ? 3   ASN A CA  1 
ATOM   2159 C C   . ASN B 2 7   ? -16.045 -11.934 36.159  1   66.71  ? 3   ASN A C   1 
ATOM   2160 O O   . ASN B 2 7   ? -16.527 -13.043 36.361  1   66.8   ? 3   ASN A O   1 
ATOM   2161 C CB  . ASN B 2 7   ? -18.191 -10.857 35.817  1   70.18  ? 3   ASN A CB  1 
ATOM   2162 C CG  . ASN B 2 7   ? -19.27  -9.945  36.358  1   73.79  ? 3   ASN A CG  1 
ATOM   2163 O OD1 . ASN B 2 7   ? -19.354 -9.708  37.576  1   76.69  ? 3   ASN A OD1 1 
ATOM   2164 N ND2 . ASN B 2 7   ? -20.078 -9.409  35.451  1   73.37  ? 3   ASN A ND2 1 
ATOM   2165 N N   . PHE B 2 8   ? -14.84  -11.758 35.598  1   64.17  ? 4   PHE A N   1 
ATOM   2166 C CA  . PHE B 2 8   ? -13.964 -12.902 35.377  1   61.34  ? 4   PHE A CA  1 
ATOM   2167 C C   . PHE B 2 8   ? -12.876 -13.004 36.45   1   64.26  ? 4   PHE A C   1 
ATOM   2168 O O   . PHE B 2 8   ? -12.437 -12.013 37.031  1   66.69  ? 4   PHE A O   1 
ATOM   2169 C CB  . PHE B 2 8   ? -13.408 -12.865 33.968  1   58.03  ? 4   PHE A CB  1 
ATOM   2170 C CG  . PHE B 2 8   ? -14.482 -13.04  32.91   1   55.44  ? 4   PHE A CG  1 
ATOM   2171 C CD1 . PHE B 2 8   ? -14.973 -14.307 32.609  1   53.83  ? 4   PHE A CD1 1 
ATOM   2172 C CD2 . PHE B 2 8   ? -14.983 -11.949 32.201  1   54.85  ? 4   PHE A CD2 1 
ATOM   2173 C CE1 . PHE B 2 8   ? -15.937 -14.482 31.616  1   52.59  ? 4   PHE A CE1 1 
ATOM   2174 C CE2 . PHE B 2 8   ? -15.958 -12.13  31.23   1   53.46  ? 4   PHE A CE2 1 
ATOM   2175 C CZ  . PHE B 2 8   ? -16.433 -13.393 30.922  1   51.57  ? 4   PHE A CZ  1 
ATOM   2176 N N   . GLN B 2 9   ? -12.514 -14.252 36.762  1   64.36  ? 5   GLN A N   1 
ATOM   2177 C CA  . GLN B 2 9   ? -11.387 -14.605 37.607  1   66.65  ? 5   GLN A CA  1 
ATOM   2178 C C   . GLN B 2 9   ? -10.381 -15.376 36.755  1   65.41  ? 5   GLN A C   1 
ATOM   2179 O O   . GLN B 2 9   ? -10.716 -16.443 36.249  1   64.09  ? 5   GLN A O   1 
ATOM   2180 C CB  . GLN B 2 9   ? -11.901 -15.442 38.778  1   68.89  ? 5   GLN A CB  1 
ATOM   2181 C CG  . GLN B 2 9   ? -10.816 -15.871 39.76   1   73.6   ? 5   GLN A CG  1 
ATOM   2182 C CD  . GLN B 2 9   ? -10.063 -14.696 40.36   1   78.6   ? 5   GLN A CD  1 
ATOM   2183 O OE1 . GLN B 2 9   ? -10.631 -13.834 41.042  1   83.41  ? 5   GLN A OE1 1 
ATOM   2184 N NE2 . GLN B 2 9   ? -8.769  -14.622 40.083  1   79.1   ? 5   GLN A NE2 1 
ATOM   2185 N N   . LYS B 2 10  ? -9.177  -14.826 36.535  1   66.99  ? 6   LYS A N   1 
ATOM   2186 C CA  . LYS B 2 10  ? -8.196  -15.562 35.752  1   67.56  ? 6   LYS A CA  1 
ATOM   2187 C C   . LYS B 2 10  ? -7.697  -16.719 36.611  1   67.16  ? 6   LYS A C   1 
ATOM   2188 O O   . LYS B 2 10  ? -7.663  -16.592 37.823  1   69.57  ? 6   LYS A O   1 
ATOM   2189 C CB  . LYS B 2 10  ? -7.127  -14.711 35.065  1   70.54  ? 6   LYS A CB  1 
ATOM   2190 C CG  . LYS B 2 10  ? -6.024  -14.149 35.94   1   84.54  ? 6   LYS A CG  1 
ATOM   2191 C CD  . LYS B 2 10  ? -4.764  -13.706 35.181  1   91.52  ? 6   LYS A CD  1 
ATOM   2192 C CE  . LYS B 2 10  ? -3.95   -12.548 35.77   1   95.51  ? 6   LYS A CE  1 
ATOM   2193 N NZ  . LYS B 2 10  ? -2.973  -12.004 34.806  1   88.97  ? 6   LYS A NZ  1 
ATOM   2194 N N   . VAL B 2 11  ? -7.405  -17.854 35.968  1   66.61  ? 7   VAL A N   1 
ATOM   2195 C CA  . VAL B 2 11  ? -7.078  -19.106 36.634  1   68.26  ? 7   VAL A CA  1 
ATOM   2196 C C   . VAL B 2 11  ? -5.611  -19.419 36.348  1   69.3   ? 7   VAL A C   1 
ATOM   2197 O O   . VAL B 2 11  ? -4.864  -19.675 37.288  1   71.91  ? 7   VAL A O   1 
ATOM   2198 C CB  . VAL B 2 11  ? -7.998  -20.27  36.197  1   66.2   ? 7   VAL A CB  1 
ATOM   2199 C CG1 . VAL B 2 11  ? -7.562  -21.611 36.757  1   65.73  ? 7   VAL A CG1 1 
ATOM   2200 C CG2 . VAL B 2 11  ? -9.448  -20.033 36.589  1   65.92  ? 7   VAL A CG2 1 
ATOM   2201 N N   . GLU B 2 12  ? -5.231  -19.391 35.059  1   66.78  ? 8   GLU A N   1 
ATOM   2202 C CA  . GLU B 2 12  ? -3.857  -19.616 34.64   1   69.89  ? 8   GLU A CA  1 
ATOM   2203 C C   . GLU B 2 12  ? -3.701  -19.3   33.151  1   69.47  ? 8   GLU A C   1 
ATOM   2204 O O   . GLU B 2 12  ? -4.684  -19.236 32.411  1   66.23  ? 8   GLU A O   1 
ATOM   2205 C CB  . GLU B 2 12  ? -3.465  -21.076 34.849  1   71.66  ? 8   GLU A CB  1 
ATOM   2206 C CG  . GLU B 2 12  ? -4.364  -22.046 34.091  1   74.68  ? 8   GLU A CG  1 
ATOM   2207 C CD  . GLU B 2 12  ? -3.846  -23.462 33.977  1   77.43  ? 8   GLU A CD  1 
ATOM   2208 O OE1 . GLU B 2 12  ? -3.341  -23.88  35.03   1   87.73  ? 8   GLU A OE1 1 
ATOM   2209 O OE2 . GLU B 2 12  ? -3.971  -24.147 32.926  1   76.42  ? 8   GLU A OE2 1 
ATOM   2210 N N   . LYS B 2 13  ? -2.444  -19.136 32.714  1   70.53  ? 9   LYS A N   1 
ATOM   2211 C CA  . LYS B 2 13  ? -2.134  -18.896 31.315  1   69.47  ? 9   LYS A CA  1 
ATOM   2212 C C   . LYS B 2 13  ? -2.213  -20.221 30.558  1   67.54  ? 9   LYS A C   1 
ATOM   2213 O O   . LYS B 2 13  ? -1.839  -21.264 31.09   1   71.16  ? 9   LYS A O   1 
ATOM   2214 C CB  . LYS B 2 13  ? -0.757  -18.239 31.21   1   72.69  ? 9   LYS A CB  1 
ATOM   2215 C CG  . LYS B 2 13  ? -0.228  -18.133 29.796  1   77.66  ? 9   LYS A CG  1 
ATOM   2216 C CD  . LYS B 2 13  ? 1.064   -17.326 29.721  1   88.35  ? 9   LYS A CD  1 
ATOM   2217 C CE  . LYS B 2 13  ? 1.551   -17.194 28.304  1   90.66  ? 9   LYS A CE  1 
ATOM   2218 N NZ  . LYS B 2 13  ? 2.457   -16.046 28.202  1   101.16 ? 9   LYS A NZ  1 
ATOM   2219 N N   . ILE B 2 14  ? -2.701  -20.187 29.318  1   60.78  ? 10  ILE A N   1 
ATOM   2220 C CA  . ILE B 2 14  ? -2.871  -21.44  28.613  1   60.35  ? 10  ILE A CA  1 
ATOM   2221 C C   . ILE B 2 14  ? -2.237  -21.38  27.234  1   59.62  ? 10  ILE A C   1 
ATOM   2222 O O   . ILE B 2 14  ? -2.187  -22.399 26.548  1   62.89  ? 10  ILE A O   1 
ATOM   2223 C CB  . ILE B 2 14  ? -4.35   -21.88  28.515  1   60.93  ? 10  ILE A CB  1 
ATOM   2224 C CG1 . ILE B 2 14  ? -5.281  -20.752 28.008  1   60.59  ? 10  ILE A CG1 1 
ATOM   2225 C CG2 . ILE B 2 14  ? -4.817  -22.491 29.844  1   62.93  ? 10  ILE A CG2 1 
ATOM   2226 C CD1 . ILE B 2 14  ? -6.713  -21.18  27.74   1   56.85  ? 10  ILE A CD1 1 
ATOM   2227 N N   . GLY B 2 15  ? -1.802  -20.192 26.806  1   59.34  ? 11  GLY A N   1 
ATOM   2228 C CA  . GLY B 2 15  ? -1.362  -20.069 25.42   1   61.26  ? 11  GLY A CA  1 
ATOM   2229 C C   . GLY B 2 15  ? -0.854  -18.674 25.067  1   63.07  ? 11  GLY A C   1 
ATOM   2230 O O   . GLY B 2 15  ? -0.959  -17.737 25.859  1   63.27  ? 11  GLY A O   1 
ATOM   2231 N N   . GLU B 2 16  ? -0.297  -18.554 23.859  1   66.21  ? 12  GLU A N   1 
ATOM   2232 C CA  . GLU B 2 16  ? -0.025  -17.252 23.281  1   77.25  ? 12  GLU A CA  1 
ATOM   2233 C C   . GLU B 2 16  ? 0.139   -17.407 21.782  1   88.17  ? 12  GLU A C   1 
ATOM   2234 O O   . GLU B 2 16  ? 0.422   -18.492 21.279  1   87.94  ? 12  GLU A O   1 
ATOM   2235 C CB  . GLU B 2 16  ? 1.189   -16.533 23.861  1   77.76  ? 12  GLU A CB  1 
ATOM   2236 C CG  . GLU B 2 16  ? 2.322   -17.495 24.172  1   82.54  ? 12  GLU A CG  1 
ATOM   2237 C CD  . GLU B 2 16  ? 3.382   -16.844 25.046  1   94.56  ? 12  GLU A CD  1 
ATOM   2238 O OE1 . GLU B 2 16  ? 4.09    -17.608 25.751  1   96.68  ? 12  GLU A OE1 1 
ATOM   2239 O OE2 . GLU B 2 16  ? 3.508   -15.591 25.005  1   92.59  ? 12  GLU A OE2 1 
ATOM   2240 N N   . GLY B 2 17  ? -0.078  -16.282 21.102  1   105.04 ? 13  GLY A N   1 
ATOM   2241 C CA  . GLY B 2 17  ? 0.113   -16.166 19.671  1   113.65 ? 13  GLY A CA  1 
ATOM   2242 C C   . GLY B 2 17  ? 0.575   -14.758 19.307  1   116.61 ? 13  GLY A C   1 
ATOM   2243 O O   . GLY B 2 17  ? 1.11    -14.023 20.137  1   109.02 ? 13  GLY A O   1 
ATOM   2244 N N   . THR B 2 18  ? 0.285   -14.388 18.06   1   125.9  ? 14  THR A N   1 
ATOM   2245 C CA  . THR B 2 18  ? 0.766   -13.169 17.438  1   119.71 ? 14  THR A CA  1 
ATOM   2246 C C   . THR B 2 18  ? 0.469   -11.947 18.316  1   116.93 ? 14  THR A C   1 
ATOM   2247 O O   . THR B 2 18  ? 1.378   -11.147 18.55   1   106.79 ? 14  THR A O   1 
ATOM   2248 C CB  . THR B 2 18  ? 0.245   -13.104 15.991  1   126.75 ? 14  THR A CB  1 
ATOM   2249 O OG1 . THR B 2 18  ? 0.61    -11.84  15.449  1   137.41 ? 14  THR A OG1 1 
ATOM   2250 C CG2 . THR B 2 18  ? -1.251  -13.355 15.826  1   107.55 ? 14  THR A CG2 1 
ATOM   2251 N N   . TYR B 2 19  ? -0.779  -11.819 18.825  1   121.72 ? 15  TYR A N   1 
ATOM   2252 C CA  . TYR B 2 19  ? -1.287  -10.542 19.328  1   123.21 ? 15  TYR A CA  1 
ATOM   2253 C C   . TYR B 2 19  ? -1.477  -10.491 20.844  1   113.04 ? 15  TYR A C   1 
ATOM   2254 O O   . TYR B 2 19  ? -1.699  -9.405  21.414  1   100.38 ? 15  TYR A O   1 
ATOM   2255 C CB  . TYR B 2 19  ? -2.446  -9.989  18.496  1   136.25 ? 15  TYR A CB  1 
ATOM   2256 C CG  . TYR B 2 19  ? -1.944  -9.196  17.292  1   159.98 ? 15  TYR A CG  1 
ATOM   2257 C CD1 . TYR B 2 19  ? -1.309  -7.966  17.463  1   161.38 ? 15  TYR A CD1 1 
ATOM   2258 C CD2 . TYR B 2 19  ? -2.062  -9.686  15.99   1   163.46 ? 15  TYR A CD2 1 
ATOM   2259 C CE1 . TYR B 2 19  ? -0.819  -7.25   16.377  1   154.92 ? 15  TYR A CE1 1 
ATOM   2260 C CE2 . TYR B 2 19  ? -1.567  -8.981  14.898  1   146.96 ? 15  TYR A CE2 1 
ATOM   2261 C CZ  . TYR B 2 19  ? -0.951  -7.754  15.091  1   146.45 ? 15  TYR A CZ  1 
ATOM   2262 O OH  . TYR B 2 19  ? -0.477  -7.047  14.019  1   136.95 ? 15  TYR A OH  1 
ATOM   2263 N N   . GLY B 2 20  ? -1.365  -11.657 21.494  1   104.74 ? 16  GLY A N   1 
ATOM   2264 C CA  . GLY B 2 20  ? -1.183  -11.637 22.941  1   92.66  ? 16  GLY A CA  1 
ATOM   2265 C C   . GLY B 2 20  ? -1.24   -13.013 23.605  1   81.17  ? 16  GLY A C   1 
ATOM   2266 O O   . GLY B 2 20  ? -1.193  -14.045 22.944  1   76.55  ? 16  GLY A O   1 
ATOM   2267 N N   . VAL B 2 21  ? -1.311  -12.987 24.939  1   77.95  ? 17  VAL A N   1 
ATOM   2268 C CA  . VAL B 2 21  ? -1.525  -14.161 25.768  1   76.21  ? 17  VAL A CA  1 
ATOM   2269 C C   . VAL B 2 21  ? -2.99   -14.614 25.679  1   71.83  ? 17  VAL A C   1 
ATOM   2270 O O   . VAL B 2 21  ? -3.881  -13.829 25.362  1   72.85  ? 17  VAL A O   1 
ATOM   2271 C CB  . VAL B 2 21  ? -1.118  -13.832 27.221  1   77.85  ? 17  VAL A CB  1 
ATOM   2272 C CG1 . VAL B 2 21  ? -1.894  -12.66  27.817  1   83.38  ? 17  VAL A CG1 1 
ATOM   2273 C CG2 . VAL B 2 21  ? -1.238  -15.045 28.135  1   79.4   ? 17  VAL A CG2 1 
ATOM   2274 N N   . VAL B 2 22  ? -3.223  -15.895 25.979  1   64.4   ? 18  VAL A N   1 
ATOM   2275 C CA  . VAL B 2 22  ? -4.544  -16.45  26.222  1   59.11  ? 18  VAL A CA  1 
ATOM   2276 C C   . VAL B 2 22  ? -4.587  -17.001 27.646  1   60.78  ? 18  VAL A C   1 
ATOM   2277 O O   . VAL B 2 22  ? -3.665  -17.667 28.112  1   63.51  ? 18  VAL A O   1 
ATOM   2278 C CB  . VAL B 2 22  ? -4.89   -17.538 25.196  1   55.29  ? 18  VAL A CB  1 
ATOM   2279 C CG1 . VAL B 2 22  ? -6.268  -18.134 25.456  1   53.6   ? 18  VAL A CG1 1 
ATOM   2280 C CG2 . VAL B 2 22  ? -4.761  -17.029 23.766  1   52.75  ? 18  VAL A CG2 1 
ATOM   2281 N N   . TYR B 2 23  ? -5.669  -16.699 28.355  1   59.75  ? 19  TYR A N   1 
ATOM   2282 C CA  . TYR B 2 23  ? -5.819  -17.11  29.735  1   59.78  ? 19  TYR A CA  1 
ATOM   2283 C C   . TYR B 2 23  ? -7.106  -17.923 29.896  1   58.54  ? 19  TYR A C   1 
ATOM   2284 O O   . TYR B 2 23  ? -8.124  -17.689 29.233  1   55.52  ? 19  TYR A O   1 
ATOM   2285 C CB  . TYR B 2 23  ? -5.922  -15.821 30.543  1   63.62  ? 19  TYR A CB  1 
ATOM   2286 C CG  . TYR B 2 23  ? -4.637  -15.211 31.077  1   70.82  ? 19  TYR A CG  1 
ATOM   2287 C CD1 . TYR B 2 23  ? -4.046  -15.75  32.213  1   76.65  ? 19  TYR A CD1 1 
ATOM   2288 C CD2 . TYR B 2 23  ? -4.053  -14.082 30.503  1   73.28  ? 19  TYR A CD2 1 
ATOM   2289 C CE1 . TYR B 2 23  ? -2.902  -15.199 32.763  1   87.67  ? 19  TYR A CE1 1 
ATOM   2290 C CE2 . TYR B 2 23  ? -2.898  -13.527 31.037  1   82.38  ? 19  TYR A CE2 1 
ATOM   2291 C CZ  . TYR B 2 23  ? -2.324  -14.084 32.179  1   93.44  ? 19  TYR A CZ  1 
ATOM   2292 O OH  . TYR B 2 23  ? -1.194  -13.616 32.812  1   101.32 ? 19  TYR A OH  1 
ATOM   2293 N N   . LYS B 2 24  ? -7.073  -18.892 30.806  1   56.46  ? 20  LYS A N   1 
ATOM   2294 C CA  . LYS B 2 24  ? -8.29   -19.576 31.196  1   53.03  ? 20  LYS A CA  1 
ATOM   2295 C C   . LYS B 2 24  ? -8.908  -18.815 32.359  1   54.4   ? 20  LYS A C   1 
ATOM   2296 O O   . LYS B 2 24  ? -8.222  -18.404 33.3    1   56.88  ? 20  LYS A O   1 
ATOM   2297 C CB  . LYS B 2 24  ? -7.969  -21.018 31.58   1   53.39  ? 20  LYS A CB  1 
ATOM   2298 C CG  . LYS B 2 24  ? -9.108  -21.853 32.11   1   54.17  ? 20  LYS A CG  1 
ATOM   2299 C CD  . LYS B 2 24  ? -8.669  -23.069 32.917  1   56.04  ? 20  LYS A CD  1 
ATOM   2300 C CE  . LYS B 2 24  ? -9.794  -24.027 33.109  1   56.82  ? 20  LYS A CE  1 
ATOM   2301 N NZ  . LYS B 2 24  ? -9.395  -25.21  33.869  1   58.56  ? 20  LYS A NZ  1 
ATOM   2302 N N   . ALA B 2 25  ? -10.233 -18.617 32.306  1   53.04  ? 21  ALA A N   1 
ATOM   2303 C CA  . ALA B 2 25  ? -10.873 -17.873 33.383  1   52.47  ? 21  ALA A CA  1 
ATOM   2304 C C   . ALA B 2 25  ? -12.247 -18.457 33.685  1   51.64  ? 21  ALA A C   1 
ATOM   2305 O O   . ALA B 2 25  ? -12.776 -19.278 32.926  1   50.27  ? 21  ALA A O   1 
ATOM   2306 C CB  . ALA B 2 25  ? -10.932 -16.425 33.019  1   52.31  ? 21  ALA A CB  1 
ATOM   2307 N N   A ARG B 2 26  ? -12.782 -18.04  34.834  0.5 53.27  ? 22  ARG A N   1 
ATOM   2308 N N   B ARG B 2 26  ? -12.831 -17.993 34.786  0.5 53.39  ? 22  ARG A N   1 
ATOM   2309 C CA  A ARG B 2 26  ? -14.071 -18.465 35.358  0.5 53.25  ? 22  ARG A CA  1 
ATOM   2310 C CA  B ARG B 2 26  ? -14.087 -18.521 35.282  0.5 53.44  ? 22  ARG A CA  1 
ATOM   2311 C C   A ARG B 2 26  ? -14.994 -17.25  35.444  0.5 53.82  ? 22  ARG A C   1 
ATOM   2312 C C   B ARG B 2 26  ? -15.043 -17.356 35.54   0.5 54.09  ? 22  ARG A C   1 
ATOM   2313 O O   A ARG B 2 26  ? -14.646 -16.245 36.066  0.5 55.04  ? 22  ARG A O   1 
ATOM   2314 O O   B ARG B 2 26  ? -14.754 -16.475 36.351  0.5 55.39  ? 22  ARG A O   1 
ATOM   2315 C CB  A ARG B 2 26  ? -13.927 -19.062 36.767  0.5 55     ? 22  ARG A CB  1 
ATOM   2316 C CB  B ARG B 2 26  ? -13.801 -19.412 36.5    0.5 55.17  ? 22  ARG A CB  1 
ATOM   2317 C CG  A ARG B 2 26  ? -15.242 -19.255 37.514  0.5 55.78  ? 22  ARG A CG  1 
ATOM   2318 C CG  B ARG B 2 26  ? -15.015 -19.908 37.267  0.5 56.39  ? 22  ARG A CG  1 
ATOM   2319 C CD  A ARG B 2 26  ? -15.176 -20.031 38.845  0.5 57.48  ? 22  ARG A CD  1 
ATOM   2320 C CD  B ARG B 2 26  ? -14.708 -21.041 38.245  0.5 57.78  ? 22  ARG A CD  1 
ATOM   2321 N NE  A ARG B 2 26  ? -14.925 -19.234 40.053  0.5 59.97  ? 22  ARG A NE  1 
ATOM   2322 N NE  B ARG B 2 26  ? -14.534 -22.329 37.56   0.5 55.98  ? 22  ARG A NE  1 
ATOM   2323 C CZ  A ARG B 2 26  ? -13.708 -19.062 40.543  0.5 61.07  ? 22  ARG A CZ  1 
ATOM   2324 C CZ  B ARG B 2 26  ? -13.436 -23.071 37.61   0.5 55.62  ? 22  ARG A CZ  1 
ATOM   2325 N NH1 A ARG B 2 26  ? -13.543 -18.364 41.652  0.5 63.63  ? 22  ARG A NH1 1 
ATOM   2326 N NH1 B ARG B 2 26  ? -13.345 -24.144 36.849  0.5 53.79  ? 22  ARG A NH1 1 
ATOM   2327 N NH2 A ARG B 2 26  ? -12.669 -19.584 39.905  0.5 59.51  ? 22  ARG A NH2 1 
ATOM   2328 N NH2 B ARG B 2 26  ? -12.427 -22.704 38.383  0.5 57.32  ? 22  ARG A NH2 1 
ATOM   2329 N N   . ASN B 2 27  ? -16.176 -17.359 34.817  1   52.59  ? 23  ASN A N   1 
ATOM   2330 C CA  . ASN B 2 27  ? -17.234 -16.373 35.02   1   52.89  ? 23  ASN A CA  1 
ATOM   2331 C C   . ASN B 2 27  ? -17.739 -16.532 36.449  1   55.11  ? 23  ASN A C   1 
ATOM   2332 O O   . ASN B 2 27  ? -18.186 -17.603 36.835  1   55.8   ? 23  ASN A O   1 
ATOM   2333 C CB  . ASN B 2 27  ? -18.369 -16.548 34.015  1   50.3   ? 23  ASN A CB  1 
ATOM   2334 C CG  . ASN B 2 27  ? -19.497 -15.564 34.228  1   50.93  ? 23  ASN A CG  1 
ATOM   2335 O OD1 . ASN B 2 27  ? -19.954 -15.32  35.362  1   52.73  ? 23  ASN A OD1 1 
ATOM   2336 N ND2 . ASN B 2 27  ? -19.965 -15.007 33.13   1   49.22  ? 23  ASN A ND2 1 
ATOM   2337 N N   . LYS B 2 28  ? -17.674 -15.478 37.25   1   57.2   ? 24  LYS A N   1 
ATOM   2338 C CA  . LYS B 2 28  ? -17.855 -15.649 38.681  1   59.57  ? 24  LYS A CA  1 
ATOM   2339 C C   . LYS B 2 28  ? -19.329 -15.702 39.035  1   59.99  ? 24  LYS A C   1 
ATOM   2340 O O   . LYS B 2 28  ? -19.661 -16.058 40.163  1   61.61  ? 24  LYS A O   1 
ATOM   2341 C CB  . LYS B 2 28  ? -17.212 -14.503 39.472  1   62.99  ? 24  LYS A CB  1 
ATOM   2342 C CG  . LYS B 2 28  ? -15.679 -14.563 39.487  1   64.68  ? 24  LYS A CG  1 
ATOM   2343 C CD  . LYS B 2 28  ? -15.061 -13.481 40.374  1   68.94  ? 24  LYS A CD  1 
ATOM   2344 C CE  . LYS B 2 28  ? -14.78  -12.181 39.659  1   69.42  ? 24  LYS A CE  1 
ATOM   2345 N NZ  . LYS B 2 28  ? -14.416 -11.129 40.614  1   71.28  ? 24  LYS A NZ  1 
ATOM   2346 N N   . LEU B 2 29  ? -20.196 -15.321 38.088  1   58.66  ? 25  LEU A N   1 
ATOM   2347 C CA  . LEU B 2 29  ? -21.627 -15.247 38.353  1   59.17  ? 25  LEU A CA  1 
ATOM   2348 C C   . LEU B 2 29  ? -22.321 -16.52  37.874  1   57.92  ? 25  LEU A C   1 
ATOM   2349 O O   . LEU B 2 29  ? -23.203 -17.012 38.576  1   59.84  ? 25  LEU A O   1 
ATOM   2350 C CB  . LEU B 2 29  ? -22.245 -13.981 37.777  1   58.42  ? 25  LEU A CB  1 
ATOM   2351 C CG  . LEU B 2 29  ? -21.921 -12.707 38.561  1   60.31  ? 25  LEU A CG  1 
ATOM   2352 C CD1 . LEU B 2 29  ? -22.461 -11.479 37.862  1   60.38  ? 25  LEU A CD1 1 
ATOM   2353 C CD2 . LEU B 2 29  ? -22.341 -12.716 40.02   1   62.64  ? 25  LEU A CD2 1 
ATOM   2354 N N   . THR B 2 30  ? -21.89  -17.05  36.727  1   55.17  ? 26  THR A N   1 
ATOM   2355 C CA  . THR B 2 30  ? -22.564 -18.158 36.07   1   54.75  ? 26  THR A CA  1 
ATOM   2356 C C   . THR B 2 30  ? -21.823 -19.488 36.243  1   55.7   ? 26  THR A C   1 
ATOM   2357 O O   . THR B 2 30  ? -22.395 -20.541 35.944  1   55.3   ? 26  THR A O   1 
ATOM   2358 C CB  . THR B 2 30  ? -22.781 -17.902 34.574  1   51.49  ? 26  THR A CB  1 
ATOM   2359 O OG1 . THR B 2 30  ? -21.507 -17.859 33.968  1   49.43  ? 26  THR A OG1 1 
ATOM   2360 C CG2 . THR B 2 30  ? -23.491 -16.594 34.289  1   52.12  ? 26  THR A CG2 1 
ATOM   2361 N N   . GLY B 2 31  ? -20.529 -19.43  36.602  1   56.8   ? 27  GLY A N   1 
ATOM   2362 C CA  . GLY B 2 31  ? -19.657 -20.592 36.75   1   56.21  ? 27  GLY A CA  1 
ATOM   2363 C C   . GLY B 2 31  ? -18.878 -20.888 35.47   1   55.03  ? 27  GLY A C   1 
ATOM   2364 O O   . GLY B 2 31  ? -17.952 -21.7   35.455  1   55.94  ? 27  GLY A O   1 
ATOM   2365 N N   . GLU B 2 32  ? -19.24  -20.22  34.377  1   53.23  ? 28  GLU A N   1 
ATOM   2366 C CA  . GLU B 2 32  ? -18.778 -20.669 33.073  1   51.32  ? 28  GLU A CA  1 
ATOM   2367 C C   . GLU B 2 32  ? -17.26  -20.502 32.957  1   52.29  ? 28  GLU A C   1 
ATOM   2368 O O   . GLU B 2 32  ? -16.701 -19.448 33.269  1   53.77  ? 28  GLU A O   1 
ATOM   2369 C CB  . GLU B 2 32  ? -19.486 -19.874 31.979  1   49.69  ? 28  GLU A CB  1 
ATOM   2370 C CG  . GLU B 2 32  ? -19.194 -20.409 30.59   1   47.54  ? 28  GLU A CG  1 
ATOM   2371 C CD  . GLU B 2 32  ? -19.843 -19.611 29.476  1   47.89  ? 28  GLU A CD  1 
ATOM   2372 O OE1 . GLU B 2 32  ? -20.343 -18.486 29.696  1   49.31  ? 28  GLU A OE1 1 
ATOM   2373 O OE2 . GLU B 2 32  ? -19.802 -20.12  28.341  1   48.18  ? 28  GLU A OE2 1 
ATOM   2374 N N   . VAL B 2 33  ? -16.601 -21.544 32.447  1   51.55  ? 29  VAL A N   1 
ATOM   2375 C CA  . VAL B 2 33  ? -15.169 -21.534 32.223  1   49.94  ? 29  VAL A CA  1 
ATOM   2376 C C   . VAL B 2 33  ? -14.933 -21.064 30.803  1   47.99  ? 29  VAL A C   1 
ATOM   2377 O O   . VAL B 2 33  ? -15.502 -21.621 29.883  1   48.19  ? 29  VAL A O   1 
ATOM   2378 C CB  . VAL B 2 33  ? -14.558 -22.924 32.476  1   49.66  ? 29  VAL A CB  1 
ATOM   2379 C CG1 . VAL B 2 33  ? -13.062 -22.927 32.207  1   50.25  ? 29  VAL A CG1 1 
ATOM   2380 C CG2 . VAL B 2 33  ? -14.792 -23.386 33.905  1   49.95  ? 29  VAL A CG2 1 
ATOM   2381 N N   . VAL B 2 34  ? -14.095 -20.036 30.634  1   48.45  ? 30  VAL A N   1 
ATOM   2382 C CA  . VAL B 2 34  ? -13.879 -19.443 29.317  1   46.65  ? 30  VAL A CA  1 
ATOM   2383 C C   . VAL B 2 34  ? -12.387 -19.395 28.996  1   46.5   ? 30  VAL A C   1 
ATOM   2384 O O   . VAL B 2 34  ? -11.555 -19.638 29.865  1   48.78  ? 30  VAL A O   1 
ATOM   2385 C CB  . VAL B 2 34  ? -14.476 -18.024 29.299  1   47.26  ? 30  VAL A CB  1 
ATOM   2386 C CG1 . VAL B 2 34  ? -15.977 -18.07  29.545  1   48.57  ? 30  VAL A CG1 1 
ATOM   2387 C CG2 . VAL B 2 34  ? -13.834 -17.096 30.32   1   48.58  ? 30  VAL A CG2 1 
ATOM   2388 N N   . ALA B 2 35  ? -12.061 -19.031 27.761  1   44.21  ? 31  ALA A N   1 
ATOM   2389 C CA  . ALA B 2 35  ? -10.719 -18.625 27.389  1   44.47  ? 31  ALA A CA  1 
ATOM   2390 C C   . ALA B 2 35  ? -10.753 -17.139 27.037  1   45.99  ? 31  ALA A C   1 
ATOM   2391 O O   . ALA B 2 35  ? -11.487 -16.759 26.133  1   46.26  ? 31  ALA A O   1 
ATOM   2392 C CB  . ALA B 2 35  ? -10.221 -19.441 26.218  1   41.62  ? 31  ALA A CB  1 
ATOM   2393 N N   . LEU B 2 36  ? -9.976  -16.311 27.759  1   48.14  ? 32  LEU A N   1 
ATOM   2394 C CA  . LEU B 2 36  ? -9.756  -14.914 27.413  1   49.56  ? 32  LEU A CA  1 
ATOM   2395 C C   . LEU B 2 36  ? -8.521  -14.779 26.53   1   52.07  ? 32  LEU A C   1 
ATOM   2396 O O   . LEU B 2 36  ? -7.428  -15.127 26.94   1   59.64  ? 32  LEU A O   1 
ATOM   2397 C CB  . LEU B 2 36  ? -9.544  -14.133 28.696  1   50.26  ? 32  LEU A CB  1 
ATOM   2398 C CG  . LEU B 2 36  ? -10.668 -14.235 29.719  1   50.75  ? 32  LEU A CG  1 
ATOM   2399 C CD1 . LEU B 2 36  ? -10.268 -13.418 30.96   1   52.61  ? 32  LEU A CD1 1 
ATOM   2400 C CD2 . LEU B 2 36  ? -12.002 -13.741 29.126  1   49.71  ? 32  LEU A CD2 1 
ATOM   2401 N N   . LYS B 2 37  ? -8.682  -14.268 25.315  1   52.62  ? 33  LYS A N   1 
ATOM   2402 C CA  . LYS B 2 37  ? -7.56   -13.922 24.468  1   53.63  ? 33  LYS A CA  1 
ATOM   2403 C C   . LYS B 2 37  ? -7.37   -12.41  24.513  1   57.99  ? 33  LYS A C   1 
ATOM   2404 O O   . LYS B 2 37  ? -8.153  -11.672 23.937  1   59.29  ? 33  LYS A O   1 
ATOM   2405 C CB  . LYS B 2 37  ? -7.849  -14.487 23.076  1   51.48  ? 33  LYS A CB  1 
ATOM   2406 C CG  . LYS B 2 37  ? -6.995  -13.951 21.943  1   51.9   ? 33  LYS A CG  1 
ATOM   2407 C CD  . LYS B 2 37  ? -7.418  -14.505 20.586  1   53.1   ? 33  LYS A CD  1 
ATOM   2408 C CE  . LYS B 2 37  ? -6.428  -15.372 19.881  1   55.56  ? 33  LYS A CE  1 
ATOM   2409 N NZ  . LYS B 2 37  ? -6.542  -15.364 18.418  1   51.76  ? 33  LYS A NZ  1 
ATOM   2410 N N   . LYS B 2 38  ? -6.368  -11.949 25.265  1   62.44  ? 34  LYS A N   1 
ATOM   2411 C CA  . LYS B 2 38  ? -6.01   -10.543 25.293  1   65.21  ? 34  LYS A CA  1 
ATOM   2412 C C   . LYS B 2 38  ? -5.339  -10.183 23.977  1   70.35  ? 34  LYS A C   1 
ATOM   2413 O O   . LYS B 2 38  ? -4.356  -10.819 23.609  1   73.67  ? 34  LYS A O   1 
ATOM   2414 C CB  . LYS B 2 38  ? -5.097  -10.246 26.484  1   68.14  ? 34  LYS A CB  1 
ATOM   2415 C CG  . LYS B 2 38  ? -4.836  -8.776  26.738  1   70.8   ? 34  LYS A CG  1 
ATOM   2416 C CD  . LYS B 2 38  ? -4.26   -8.468  28.115  1   75.93  ? 34  LYS A CD  1 
ATOM   2417 C CE  . LYS B 2 38  ? -2.838  -8.918  28.292  1   80.32  ? 34  LYS A CE  1 
ATOM   2418 N NZ  . LYS B 2 38  ? -2.327  -8.444  29.585  1   81.18  ? 34  LYS A NZ  1 
ATOM   2419 N N   . ILE B 2 39  ? -5.948  -9.23   23.253  1   75.2   ? 35  ILE A N   1 
ATOM   2420 C CA  . ILE B 2 39  ? -5.354  -8.506  22.138  1   75.49  ? 35  ILE A CA  1 
ATOM   2421 C C   . ILE B 2 39  ? -4.942  -7.152  22.714  1   86.22  ? 35  ILE A C   1 
ATOM   2422 O O   . ILE B 2 39  ? -5.732  -6.503  23.409  1   88.06  ? 35  ILE A O   1 
ATOM   2423 C CB  . ILE B 2 39  ? -6.344  -8.341  20.966  1   71.19  ? 35  ILE A CB  1 
ATOM   2424 C CG1 . ILE B 2 39  ? -7.122  -9.622  20.597  1   67.47  ? 35  ILE A CG1 1 
ATOM   2425 C CG2 . ILE B 2 39  ? -5.672  -7.699  19.753  1   70.26  ? 35  ILE A CG2 1 
ATOM   2426 C CD1 . ILE B 2 39  ? -6.407  -10.594 19.682  1   67.95  ? 35  ILE A CD1 1 
ATOM   2427 N N   . ARG B 2 40  ? -3.681  -6.753  22.488  1   99.82  ? 36  ARG A N   1 
ATOM   2428 C CA  . ARG B 2 40  ? -3.17   -5.548  23.129  1   108.8  ? 36  ARG A CA  1 
ATOM   2429 C C   . ARG B 2 40  ? -3.097  -4.413  22.106  1   109.07 ? 36  ARG A C   1 
ATOM   2430 O O   . ARG B 2 40  ? -2.652  -4.622  20.974  1   99.1   ? 36  ARG A O   1 
ATOM   2431 C CB  . ARG B 2 40  ? -1.886  -5.846  23.915  1   115.56 ? 36  ARG A CB  1 
ATOM   2432 C CG  . ARG B 2 40  ? -1.409  -4.695  24.789  1   118.73 ? 36  ARG A CG  1 
ATOM   2433 C CD  . ARG B 2 40  ? -0.295  -5.101  25.743  1   123.49 ? 36  ARG A CD  1 
ATOM   2434 N NE  . ARG B 2 40  ? -0.775  -5.524  27.065  1   127.42 ? 36  ARG A NE  1 
ATOM   2435 C CZ  . ARG B 2 40  ? -0.829  -4.724  28.137  1   132    ? 36  ARG A CZ  1 
ATOM   2436 N NH1 . ARG B 2 40  ? -0.537  -3.436  28.018  1   132.82 ? 36  ARG A NH1 1 
ATOM   2437 N NH2 . ARG B 2 40  ? -1.192  -5.205  29.318  1   125.38 ? 36  ARG A NH2 1 
ATOM   2438 N N   . LEU B 2 41  ? -3.527  -3.217  22.548  1   109.35 ? 37  LEU A N   1 
ATOM   2439 C CA  . LEU B 2 41  ? -3.786  -2.082  21.673  1   108.12 ? 37  LEU A CA  1 
ATOM   2440 C C   . LEU B 2 41  ? -2.795  -0.942  21.917  1   122.97 ? 37  LEU A C   1 
ATOM   2441 O O   . LEU B 2 41  ? -2.618  -0.095  21.038  1   126.47 ? 37  LEU A O   1 
ATOM   2442 C CB  . LEU B 2 41  ? -5.217  -1.582  21.86   1   96.75  ? 37  LEU A CB  1 
ATOM   2443 C CG  . LEU B 2 41  ? -6.36   -2.532  21.487  1   88.35  ? 37  LEU A CG  1 
ATOM   2444 C CD1 . LEU B 2 41  ? -7.716  -1.826  21.612  1   83.15  ? 37  LEU A CD1 1 
ATOM   2445 C CD2 . LEU B 2 41  ? -6.15   -3.084  20.097  1   82.54  ? 37  LEU A CD2 1 
ATOM   2446 N N   . ASP B 2 42  ? -2.185  -0.91   23.117  1   134.56 ? 38  ASP A N   1 
ATOM   2447 C CA  . ASP B 2 42  ? -1.303  0.186   23.503  1   138.04 ? 38  ASP A CA  1 
ATOM   2448 C C   . ASP B 2 42  ? 0.093   -0.012  22.913  1   140.85 ? 38  ASP A C   1 
ATOM   2449 O O   . ASP B 2 42  ? 0.806   0.96    22.665  1   141.55 ? 38  ASP A O   1 
ATOM   2450 C CB  . ASP B 2 42  ? -1.278  0.448   25      1   136.22 ? 38  ASP A CB  1 
ATOM   2451 C CG  . ASP B 2 42  ? -0.913  1.883   25.359  1   140.49 ? 38  ASP A CG  1 
ATOM   2452 O OD1 . ASP B 2 42  ? -0.953  2.738   24.443  1   137.4  ? 38  ASP A OD1 1 
ATOM   2453 O OD2 . ASP B 2 42  ? -0.569  2.136   26.533  1   141.37 ? 38  ASP A OD2 1 
ATOM   2454 N N   . THR B 2 43  ? 0.474   -1.281  22.698  1   141.71 ? 39  THR A N   1 
ATOM   2455 C CA  . THR B 2 43  ? 1.58    -1.619  21.808  1   144.77 ? 39  THR A CA  1 
ATOM   2456 C C   . THR B 2 43  ? 1.266   -1.134  20.388  1   150.28 ? 39  THR A C   1 
ATOM   2457 O O   . THR B 2 43  ? 2.153   -0.653  19.685  1   161.77 ? 39  THR A O   1 
ATOM   2458 C CB  . THR B 2 43  ? 1.941   -3.111  21.864  1   138.07 ? 39  THR A CB  1 
ATOM   2459 O OG1 . THR B 2 43  ? 3.043   -3.322  20.987  1   131.15 ? 39  THR A OG1 1 
ATOM   2460 C CG2 . THR B 2 43  ? 0.855   -4.046  21.366  1   130.47 ? 39  THR A CG2 1 
ATOM   2461 N N   . GLU B 2 44  ? -0.009  -1.25   19.988  1   141.6  ? 40  GLU A N   1 
ATOM   2462 C CA  . GLU B 2 44  ? -0.456  -0.975  18.631  1   124.39 ? 40  GLU A CA  1 
ATOM   2463 C C   . GLU B 2 44  ? -0.463  0.521   18.33   1   122.95 ? 40  GLU A C   1 
ATOM   2464 O O   . GLU B 2 44  ? -1.074  1.316   19.046  1   124.27 ? 40  GLU A O   1 
ATOM   2465 C CB  . GLU B 2 44  ? -1.823  -1.606  18.384  1   114.08 ? 40  GLU A CB  1 
ATOM   2466 C CG  . GLU B 2 44  ? -1.717  -3.072  17.979  1   114.99 ? 40  GLU A CG  1 
ATOM   2467 C CD  . GLU B 2 44  ? -1.045  -3.311  16.635  1   117.52 ? 40  GLU A CD  1 
ATOM   2468 O OE1 . GLU B 2 44  ? -0.235  -4.266  16.58   1   119.79 ? 40  GLU A OE1 1 
ATOM   2469 O OE2 . GLU B 2 44  ? -1.31   -2.546  15.666  1   112.45 ? 40  GLU A OE2 1 
ATOM   2470 N N   . THR B 2 45  ? 0.228   0.862   17.235  1   116.33 ? 41  THR A N   1 
ATOM   2471 C CA  . THR B 2 45  ? 0.301   2.206   16.682  1   110.63 ? 41  THR A CA  1 
ATOM   2472 C C   . THR B 2 45  ? -0.55   2.304   15.406  1   99.87  ? 41  THR A C   1 
ATOM   2473 O O   . THR B 2 45  ? -0.673  3.379   14.823  1   99.37  ? 41  THR A O   1 
ATOM   2474 C CB  . THR B 2 45  ? 1.774   2.585   16.475  1   111.72 ? 41  THR A CB  1 
ATOM   2475 O OG1 . THR B 2 45  ? 1.809   3.974   16.161  1   114.61 ? 41  THR A OG1 1 
ATOM   2476 C CG2 . THR B 2 45  ? 2.472   1.798   15.378  1   107.23 ? 41  THR A CG2 1 
ATOM   2477 N N   . GLU B 2 46  ? -1.135  1.177   14.982  1   88.56  ? 42  GLU A N   1 
ATOM   2478 C CA  . GLU B 2 46  ? -1.996  1.129   13.816  1   80.77  ? 42  GLU A CA  1 
ATOM   2479 C C   . GLU B 2 46  ? -3.413  0.754   14.23   1   73.32  ? 42  GLU A C   1 
ATOM   2480 O O   . GLU B 2 46  ? -4.154  0.187   13.449  1   71.29  ? 42  GLU A O   1 
ATOM   2481 C CB  . GLU B 2 46  ? -1.421  0.208   12.734  1   81.53  ? 42  GLU A CB  1 
ATOM   2482 C CG  . GLU B 2 46  ? -0.146  0.75    12.081  1   85.1   ? 42  GLU A CG  1 
ATOM   2483 C CD  . GLU B 2 46  ? -0.212  1.992   11.194  1   84.31  ? 42  GLU A CD  1 
ATOM   2484 O OE1 . GLU B 2 46  ? -0.698  1.873   10.038  1   79.84  ? 42  GLU A OE1 1 
ATOM   2485 O OE2 . GLU B 2 46  ? 0.215   3.083   11.663  1   87.37  ? 42  GLU A OE2 1 
ATOM   2486 N N   . GLY B 2 47  ? -3.801  1.102   15.455  1   73.85  ? 43  GLY A N   1 
ATOM   2487 C CA  . GLY B 2 47  ? -5.174  0.946   15.926  1   69.01  ? 43  GLY A CA  1 
ATOM   2488 C C   . GLY B 2 47  ? -5.529  -0.524  16.082  1   64.91  ? 43  GLY A C   1 
ATOM   2489 O O   . GLY B 2 47  ? -4.66   -1.334  16.38   1   65.37  ? 43  GLY A O   1 
ATOM   2490 N N   . VAL B 2 48  ? -6.8    -0.875  15.868  1   60.74  ? 44  VAL A N   1 
ATOM   2491 C CA  . VAL B 2 48  ? -7.162  -2.265  16.029  1   55.36  ? 44  VAL A CA  1 
ATOM   2492 C C   . VAL B 2 48  ? -6.55   -3.05   14.88   1   54.74  ? 44  VAL A C   1 
ATOM   2493 O O   . VAL B 2 48  ? -6.659  -2.678  13.713  1   54.98  ? 44  VAL A O   1 
ATOM   2494 C CB  . VAL B 2 48  ? -8.674  -2.524  16.182  1   52.81  ? 44  VAL A CB  1 
ATOM   2495 C CG1 . VAL B 2 48  ? -8.973  -4.014  16.261  1   48.87  ? 44  VAL A CG1 1 
ATOM   2496 C CG2 . VAL B 2 48  ? -9.238  -1.793  17.39   1   54.04  ? 44  VAL A CG2 1 
ATOM   2497 N N   . PRO B 2 49  ? -5.891  -4.185  15.165  1   53.5   ? 45  PRO A N   1 
ATOM   2498 C CA  . PRO B 2 49  ? -5.255  -4.95   14.107  1   52.78  ? 45  PRO A CA  1 
ATOM   2499 C C   . PRO B 2 49  ? -6.212  -5.759  13.249  1   53.3   ? 45  PRO A C   1 
ATOM   2500 O O   . PRO B 2 49  ? -7.189  -6.32   13.75   1   52.6   ? 45  PRO A O   1 
ATOM   2501 C CB  . PRO B 2 49  ? -4.324  -5.867  14.901  1   52.51  ? 45  PRO A CB  1 
ATOM   2502 C CG  . PRO B 2 49  ? -5.036  -6.066  16.18   1   51.16  ? 45  PRO A CG  1 
ATOM   2503 C CD  . PRO B 2 49  ? -5.622  -4.709  16.504  1   52.93  ? 45  PRO A CD  1 
ATOM   2504 N N   . SER B 2 50  ? -5.833  -5.896  11.973  1   51.2   ? 46  SER A N   1 
ATOM   2505 C CA  . SER B 2 50  ? -6.701  -6.436  10.964  1   48.05  ? 46  SER A CA  1 
ATOM   2506 C C   . SER B 2 50  ? -6.993  -7.897  11.279  1   47.71  ? 46  SER A C   1 
ATOM   2507 O O   . SER B 2 50  ? -8.102  -8.393  11.028  1   46.59  ? 46  SER A O   1 
ATOM   2508 C CB  . SER B 2 50  ? -6.123  -6.201  9.609   1   48.92  ? 46  SER A CB  1 
ATOM   2509 O OG  . SER B 2 50  ? -5      -7.033  9.426   1   50.36  ? 46  SER A OG  1 
ATOM   2510 N N   . THR B 2 51  ? -6.011  -8.592  11.866  1   47.81  ? 47  THR A N   1 
ATOM   2511 C CA  . THR B 2 51  ? -6.259  -9.975  12.269  1   47.72  ? 47  THR A CA  1 
ATOM   2512 C C   . THR B 2 51  ? -7.427  -10.021 13.256  1   44.17  ? 47  THR A C   1 
ATOM   2513 O O   . THR B 2 51  ? -8.241  -10.927 13.212  1   42.61  ? 47  THR A O   1 
ATOM   2514 C CB  . THR B 2 51  ? -5.032  -10.726 12.808  1   48.52  ? 47  THR A CB  1 
ATOM   2515 O OG1 . THR B 2 51  ? -4.436  -9.831  13.735  1   54.11  ? 47  THR A OG1 1 
ATOM   2516 C CG2 . THR B 2 51  ? -4.024  -11.058 11.724  1   50.91  ? 47  THR A CG2 1 
ATOM   2517 N N   . ALA B 2 52  ? -7.459  -9.094  14.193  1   44.15  ? 48  ALA A N   1 
ATOM   2518 C CA  . ALA B 2 52  ? -8.504  -9.143  15.202  1   45.99  ? 48  ALA A CA  1 
ATOM   2519 C C   . ALA B 2 52  ? -9.856  -8.702  14.605  1   46.95  ? 48  ALA A C   1 
ATOM   2520 O O   . ALA B 2 52  ? -10.887 -9.218  15.007  1   46.6   ? 48  ALA A O   1 
ATOM   2521 C CB  . ALA B 2 52  ? -8.126  -8.304  16.423  1   45.07  ? 48  ALA A CB  1 
ATOM   2522 N N   . ILE B 2 53  ? -9.849  -7.726  13.681  1   46.34  ? 49  ILE A N   1 
ATOM   2523 C CA  . ILE B 2 53  ? -11.042 -7.272  12.989  1   46.26  ? 49  ILE A CA  1 
ATOM   2524 C C   . ILE B 2 53  ? -11.706 -8.43   12.238  1   44.56  ? 49  ILE A C   1 
ATOM   2525 O O   . ILE B 2 53  ? -12.89  -8.694  12.417  1   43.76  ? 49  ILE A O   1 
ATOM   2526 C CB  . ILE B 2 53  ? -10.696 -6.071  12.099  1   46.6   ? 49  ILE A CB  1 
ATOM   2527 C CG1 . ILE B 2 53  ? -10.554 -4.835  12.956  1   47.47  ? 49  ILE A CG1 1 
ATOM   2528 C CG2 . ILE B 2 53  ? -11.726 -5.881  10.992  1   46.98  ? 49  ILE A CG2 1 
ATOM   2529 C CD1 . ILE B 2 53  ? -9.901  -3.688  12.235  1   49.24  ? 49  ILE A CD1 1 
ATOM   2530 N N   . ARG B 2 54  ? -10.912 -9.174  11.48   1   42.62  ? 50  ARG A N   1 
ATOM   2531 C CA  . ARG B 2 54  ? -11.41  -10.346 10.8    1   40.72  ? 50  ARG A CA  1 
ATOM   2532 C C   . ARG B 2 54  ? -11.835 -11.436 11.783  1   42.05  ? 50  ARG A C   1 
ATOM   2533 O O   . ARG B 2 54  ? -12.84  -12.119 11.57   1   43.28  ? 50  ARG A O   1 
ATOM   2534 C CB  . ARG B 2 54  ? -10.34  -10.899 9.85    1   39.08  ? 50  ARG A CB  1 
ATOM   2535 C CG  . ARG B 2 54  ? -10.044 -9.94   8.701   1   39.38  ? 50  ARG A CG  1 
ATOM   2536 C CD  . ARG B 2 54  ? -9.074  -10.566 7.697   1   37.61  ? 50  ARG A CD  1 
ATOM   2537 N NE  . ARG B 2 54  ? -8.84   -9.674  6.56    1   38.26  ? 50  ARG A NE  1 
ATOM   2538 C CZ  . ARG B 2 54  ? -7.795  -9.864  5.731   1   38.85  ? 50  ARG A CZ  1 
ATOM   2539 N NH1 . ARG B 2 54  ? -6.966  -10.891 5.917   1   37.53  ? 50  ARG A NH1 1 
ATOM   2540 N NH2 . ARG B 2 54  ? -7.575  -9.022  4.739   1   38.18  ? 50  ARG A NH2 1 
ATOM   2541 N N   . GLU B 2 55  ? -11.044 -11.696 12.814  1   42.1   ? 51  GLU A N   1 
ATOM   2542 C CA  . GLU B 2 55  ? -11.386 -12.82  13.671  1   41.41  ? 51  GLU A CA  1 
ATOM   2543 C C   . GLU B 2 55  ? -12.743 -12.562 14.342  1   40.09  ? 51  GLU A C   1 
ATOM   2544 O O   . GLU B 2 55  ? -13.552 -13.469 14.403  1   38.51  ? 51  GLU A O   1 
ATOM   2545 C CB  . GLU B 2 55  ? -10.304 -13.197 14.693  1   41.87  ? 51  GLU A CB  1 
ATOM   2546 C CG  . GLU B 2 55  ? -10.783 -14.292 15.642  1   44.82  ? 51  GLU A CG  1 
ATOM   2547 C CD  . GLU B 2 55  ? -9.702  -15.047 16.407  1   50.8   ? 51  GLU A CD  1 
ATOM   2548 O OE1 . GLU B 2 55  ? -8.807  -14.328 16.903  1   48.03  ? 51  GLU A OE1 1 
ATOM   2549 O OE2 . GLU B 2 55  ? -9.781  -16.322 16.525  1   53.38  ? 51  GLU A OE2 1 
ATOM   2550 N N   . ILE B 2 56  ? -12.952 -11.361 14.892  1   39.87  ? 52  ILE A N   1 
ATOM   2551 C CA  . ILE B 2 56  ? -14.155 -11.049 15.632  1   42.04  ? 52  ILE A CA  1 
ATOM   2552 C C   . ILE B 2 56  ? -15.357 -11.025 14.679  1   45.19  ? 52  ILE A C   1 
ATOM   2553 O O   . ILE B 2 56  ? -16.359 -11.708 14.928  1   46.15  ? 52  ILE A O   1 
ATOM   2554 C CB  . ILE B 2 56  ? -14.016 -9.73   16.404  1   43.16  ? 52  ILE A CB  1 
ATOM   2555 C CG1 . ILE B 2 56  ? -12.86  -9.765  17.396  1   43.65  ? 52  ILE A CG1 1 
ATOM   2556 C CG2 . ILE B 2 56  ? -15.337 -9.388  17.106  1   44.25  ? 52  ILE A CG2 1 
ATOM   2557 C CD1 . ILE B 2 56  ? -12.394 -8.394  17.854  1   45.35  ? 52  ILE A CD1 1 
ATOM   2558 N N   . SER B 2 57  ? -15.251 -10.241 13.592  1   45.63  ? 53  SER A N   1 
ATOM   2559 C CA  . SER B 2 57  ? -16.335 -10.101 12.627  1   47.58  ? 53  SER A CA  1 
ATOM   2560 C C   . SER B 2 57  ? -16.762 -11.471 12.073  1   46.75  ? 53  SER A C   1 
ATOM   2561 O O   . SER B 2 57  ? -17.954 -11.772 11.993  1   47.48  ? 53  SER A O   1 
ATOM   2562 C CB  . SER B 2 57  ? -16.023 -9.11   11.536  1   47.21  ? 53  SER A CB  1 
ATOM   2563 O OG  . SER B 2 57  ? -14.984 -9.647  10.729  1   50.84  ? 53  SER A OG  1 
ATOM   2564 N N   . LEU B 2 58  ? -15.803 -12.339 11.748  1   42.52  ? 54  LEU A N   1 
ATOM   2565 C CA  . LEU B 2 58  ? -16.169 -13.595 11.126  1   41.12  ? 54  LEU A CA  1 
ATOM   2566 C C   . LEU B 2 58  ? -16.722 -14.559 12.174  1   45.62  ? 54  LEU A C   1 
ATOM   2567 O O   . LEU B 2 58  ? -17.66  -15.31  11.883  1   50.93  ? 54  LEU A O   1 
ATOM   2568 C CB  . LEU B 2 58  ? -15.057 -14.196 10.285  1   36.88  ? 54  LEU A CB  1 
ATOM   2569 C CG  . LEU B 2 58  ? -14.547 -13.237 9.219   1   38.38  ? 54  LEU A CG  1 
ATOM   2570 C CD1 . LEU B 2 58  ? -13.365 -13.774 8.445   1   36.83  ? 54  LEU A CD1 1 
ATOM   2571 C CD2 . LEU B 2 58  ? -15.712 -12.957 8.329   1   37.4   ? 54  LEU A CD2 1 
ATOM   2572 N N   . LEU B 2 59  ? -16.201 -14.514 13.407  1   45.04  ? 55  LEU A N   1 
ATOM   2573 C CA  . LEU B 2 59  ? -16.6   -15.512 14.388  1   44.91  ? 55  LEU A CA  1 
ATOM   2574 C C   . LEU B 2 59  ? -17.983 -15.204 14.946  1   47.24  ? 55  LEU A C   1 
ATOM   2575 O O   . LEU B 2 59  ? -18.591 -16.093 15.547  1   45.71  ? 55  LEU A O   1 
ATOM   2576 C CB  . LEU B 2 59  ? -15.597 -15.662 15.528  1   43.35  ? 55  LEU A CB  1 
ATOM   2577 C CG  . LEU B 2 59  ? -14.446 -16.635 15.265  1   43.93  ? 55  LEU A CG  1 
ATOM   2578 C CD1 . LEU B 2 59  ? -13.581 -16.748 16.504  1   43.67  ? 55  LEU A CD1 1 
ATOM   2579 C CD2 . LEU B 2 59  ? -14.954 -18.003 14.839  1   41.82  ? 55  LEU A CD2 1 
ATOM   2580 N N   . LYS B 2 60  ? -18.394 -13.931 14.841  1   52.97  ? 56  LYS A N   1 
ATOM   2581 C CA  . LYS B 2 60  ? -19.713 -13.471 15.274  1   58.32  ? 56  LYS A CA  1 
ATOM   2582 C C   . LYS B 2 60  ? -20.786 -14.199 14.469  1   57.08  ? 56  LYS A C   1 
ATOM   2583 O O   . LYS B 2 60  ? -21.747 -14.678 15.059  1   57.42  ? 56  LYS A O   1 
ATOM   2584 C CB  . LYS B 2 60  ? -19.856 -11.943 15.243  1   58     ? 56  LYS A CB  1 
ATOM   2585 C CG  . LYS B 2 60  ? -19.351 -11.375 16.559  1   64.33  ? 56  LYS A CG  1 
ATOM   2586 C CD  . LYS B 2 60  ? -19.425 -9.89   16.893  1   73.31  ? 56  LYS A CD  1 
ATOM   2587 C CE  . LYS B 2 60  ? -20.714 -9.412  17.488  1   77.14  ? 56  LYS A CE  1 
ATOM   2588 N NZ  . LYS B 2 60  ? -21.622 -9.182  16.366  1   82.37  ? 56  LYS A NZ  1 
ATOM   2589 N N   . GLU B 2 61  ? -20.519 -14.349 13.167  1   55.58  ? 57  GLU A N   1 
ATOM   2590 C CA  . GLU B 2 61  ? -21.392 -14.96  12.182  1   58.29  ? 57  GLU A CA  1 
ATOM   2591 C C   . GLU B 2 61  ? -21.441 -16.49  12.297  1   58.34  ? 57  GLU A C   1 
ATOM   2592 O O   . GLU B 2 61  ? -22.474 -17.107 12.011  1   65.87  ? 57  GLU A O   1 
ATOM   2593 C CB  . GLU B 2 61  ? -20.859 -14.6   10.789  1   62.42  ? 57  GLU A CB  1 
ATOM   2594 C CG  . GLU B 2 61  ? -21.061 -13.127 10.437  1   69.27  ? 57  GLU A CG  1 
ATOM   2595 C CD  . GLU B 2 61  ? -21.121 -12.736 8.969   1   71.22  ? 57  GLU A CD  1 
ATOM   2596 O OE1 . GLU B 2 61  ? -21.294 -11.515 8.735   1   83.56  ? 57  GLU A OE1 1 
ATOM   2597 O OE2 . GLU B 2 61  ? -21.058 -13.627 8.073   1   65.42  ? 57  GLU A OE2 1 
ATOM   2598 N N   . LEU B 2 62  ? -20.314 -17.109 12.64   1   49.58  ? 58  LEU A N   1 
ATOM   2599 C CA  . LEU B 2 62  ? -20.193 -18.553 12.538  1   48.52  ? 58  LEU A CA  1 
ATOM   2600 C C   . LEU B 2 62  ? -20.613 -19.202 13.846  1   49.32  ? 58  LEU A C   1 
ATOM   2601 O O   . LEU B 2 62  ? -19.822 -19.301 14.777  1   56.08  ? 58  LEU A O   1 
ATOM   2602 C CB  . LEU B 2 62  ? -18.754 -18.935 12.207  1   42.22  ? 58  LEU A CB  1 
ATOM   2603 C CG  . LEU B 2 62  ? -18.216 -18.332 10.914  1   44.41  ? 58  LEU A CG  1 
ATOM   2604 C CD1 . LEU B 2 62  ? -16.705 -18.554 10.852  1   40.86  ? 58  LEU A CD1 1 
ATOM   2605 C CD2 . LEU B 2 62  ? -18.88  -18.871 9.647   1   41.28  ? 58  LEU A CD2 1 
ATOM   2606 N N   . ASN B 2 63  ? -21.836 -19.7   13.881  1   48.84  ? 59  ASN A N   1 
ATOM   2607 C CA  . ASN B 2 63  ? -22.31  -20.438 15.03   1   51.9   ? 59  ASN A CA  1 
ATOM   2608 C C   . ASN B 2 63  ? -22.46  -21.897 14.64   1   47.32  ? 59  ASN A C   1 
ATOM   2609 O O   . ASN B 2 63  ? -23.353 -22.233 13.873  1   51.56  ? 59  ASN A O   1 
ATOM   2610 C CB  . ASN B 2 63  ? -23.65  -19.913 15.52   1   60.21  ? 59  ASN A CB  1 
ATOM   2611 C CG  . ASN B 2 63  ? -23.394 -19.026 16.7    1   77.94  ? 59  ASN A CG  1 
ATOM   2612 O OD1 . ASN B 2 63  ? -23.684 -19.437 17.828  1   99.1   ? 59  ASN A OD1 1 
ATOM   2613 N ND2 . ASN B 2 63  ? -22.748 -17.89  16.463  1   79.82  ? 59  ASN A ND2 1 
ATOM   2614 N N   . HIS B 2 64  ? -21.618 -22.748 15.22   1   41.36  ? 60  HIS A N   1 
ATOM   2615 C CA  . HIS B 2 64  ? -21.577 -24.124 14.789  1   40.54  ? 60  HIS A CA  1 
ATOM   2616 C C   . HIS B 2 64  ? -20.896 -24.945 15.881  1   42.6   ? 60  HIS A C   1 
ATOM   2617 O O   . HIS B 2 64  ? -19.962 -24.49  16.533  1   44.83  ? 60  HIS A O   1 
ATOM   2618 C CB  . HIS B 2 64  ? -20.945 -24.234 13.391  1   37.92  ? 60  HIS A CB  1 
ATOM   2619 C CG  . HIS B 2 64  ? -21.096 -25.619 12.878  1   38.34  ? 60  HIS A CG  1 
ATOM   2620 N ND1 . HIS B 2 64  ? -20.267 -26.663 13.275  1   37.57  ? 60  HIS A ND1 1 
ATOM   2621 C CD2 . HIS B 2 64  ? -22.013 -26.148 12.039  1   35.71  ? 60  HIS A CD2 1 
ATOM   2622 C CE1 . HIS B 2 64  ? -20.692 -27.8   12.704  1   36.31  ? 60  HIS A CE1 1 
ATOM   2623 N NE2 . HIS B 2 64  ? -21.723 -27.485 11.921  1   36.04  ? 60  HIS A NE2 1 
ATOM   2624 N N   . PRO B 2 65  ? -21.392 -26.165 16.173  1   45.48  ? 61  PRO A N   1 
ATOM   2625 C CA  . PRO B 2 65  ? -20.834 -26.954 17.268  1   42.73  ? 61  PRO A CA  1 
ATOM   2626 C C   . PRO B 2 65  ? -19.359 -27.299 17.111  1   41.68  ? 61  PRO A C   1 
ATOM   2627 O O   . PRO B 2 65  ? -18.7   -27.629 18.092  1   45.01  ? 61  PRO A O   1 
ATOM   2628 C CB  . PRO B 2 65  ? -21.769 -28.177 17.32   1   43.41  ? 61  PRO A CB  1 
ATOM   2629 C CG  . PRO B 2 65  ? -22.436 -28.226 15.97   1   44.49  ? 61  PRO A CG  1 
ATOM   2630 C CD  . PRO B 2 65  ? -22.588 -26.774 15.554  1   44.4   ? 61  PRO A CD  1 
ATOM   2631 N N   . ASN B 2 66  ? -18.845 -27.192 15.888  1   38.59  ? 62  ASN A N   1 
ATOM   2632 C CA  . ASN B 2 66  ? -17.462 -27.528 15.617  1   38.56  ? 62  ASN A CA  1 
ATOM   2633 C C   . ASN B 2 66  ? -16.651 -26.302 15.192  1   39.79  ? 62  ASN A C   1 
ATOM   2634 O O   . ASN B 2 66  ? -15.603 -26.433 14.566  1   38.01  ? 62  ASN A O   1 
ATOM   2635 C CB  . ASN B 2 66  ? -17.368 -28.567 14.522  1   36.9   ? 62  ASN A CB  1 
ATOM   2636 C CG  . ASN B 2 66  ? -18.149 -29.776 14.947  1   39.5   ? 62  ASN A CG  1 
ATOM   2637 O OD1 . ASN B 2 66  ? -19.125 -30.12  14.289  1   47.13  ? 62  ASN A OD1 1 
ATOM   2638 N ND2 . ASN B 2 66  ? -17.789 -30.423 16.038  1   37.46  ? 62  ASN A ND2 1 
ATOM   2639 N N   . ILE B 2 67  ? -17.162 -25.107 15.508  1   40.22  ? 63  ILE A N   1 
ATOM   2640 C CA  . ILE B 2 67  ? -16.363 -23.909 15.421  1   37.1   ? 63  ILE A CA  1 
ATOM   2641 C C   . ILE B 2 67  ? -16.34  -23.347 16.835  1   41.21  ? 63  ILE A C   1 
ATOM   2642 O O   . ILE B 2 67  ? -17.341 -23.391 17.541  1   44.61  ? 63  ILE A O   1 
ATOM   2643 C CB  . ILE B 2 67  ? -16.961 -22.936 14.398  1   34.51  ? 63  ILE A CB  1 
ATOM   2644 C CG1 . ILE B 2 67  ? -17.025 -23.57  12.985  1   32.05  ? 63  ILE A CG1 1 
ATOM   2645 C CG2 . ILE B 2 67  ? -16.233 -21.584 14.415  1   31.74  ? 63  ILE A CG2 1 
ATOM   2646 C CD1 . ILE B 2 67  ? -17.663 -22.654 11.936  1   31.84  ? 63  ILE A CD1 1 
ATOM   2647 N N   . VAL B 2 68  ? -15.168 -22.88  17.266  1   40.84  ? 64  VAL A N   1 
ATOM   2648 C CA  . VAL B 2 68  ? -15.004 -22.371 18.619  1   39.39  ? 64  VAL A CA  1 
ATOM   2649 C C   . VAL B 2 68  ? -15.907 -21.163 18.745  1   38.04  ? 64  VAL A C   1 
ATOM   2650 O O   . VAL B 2 68  ? -15.993 -20.364 17.808  1   38.96  ? 64  VAL A O   1 
ATOM   2651 C CB  . VAL B 2 68  ? -13.531 -21.947 18.849  1   39.57  ? 64  VAL A CB  1 
ATOM   2652 C CG1 . VAL B 2 68  ? -13.103 -20.771 17.936  1   36.33  ? 64  VAL A CG1 1 
ATOM   2653 C CG2 . VAL B 2 68  ? -13.292 -21.651 20.328  1   39.29  ? 64  VAL A CG2 1 
ATOM   2654 N N   . LYS B 2 69  ? -16.535 -21.025 19.905  1   39.7   ? 65  LYS A N   1 
ATOM   2655 C CA  . LYS B 2 69  ? -17.572 -20.021 20.061  1   39.6   ? 65  LYS A CA  1 
ATOM   2656 C C   . LYS B 2 69  ? -17.027 -18.768 20.734  1   40.59  ? 65  LYS A C   1 
ATOM   2657 O O   . LYS B 2 69  ? -16.564 -18.815 21.877  1   43.28  ? 65  LYS A O   1 
ATOM   2658 C CB  . LYS B 2 69  ? -18.761 -20.543 20.874  1   44.01  ? 65  LYS A CB  1 
ATOM   2659 C CG  . LYS B 2 69  ? -19.88  -19.489 20.971  1   47.91  ? 65  LYS A CG  1 
ATOM   2660 C CD  . LYS B 2 69  ? -21.259 -20.086 21.191  1   59.23  ? 65  LYS A CD  1 
ATOM   2661 C CE  . LYS B 2 69  ? -22.352 -19.02  21.279  1   64.78  ? 65  LYS A CE  1 
ATOM   2662 N NZ  . LYS B 2 69  ? -22.519 -18.233 20.043  1   67.28  ? 65  LYS A NZ  1 
ATOM   2663 N N   . LEU B 2 70  ? -17.168 -17.638 20.037  1   39.73  ? 66  LEU A N   1 
ATOM   2664 C CA  . LEU B 2 70  ? -16.903 -16.321 20.588  1   41.29  ? 66  LEU A CA  1 
ATOM   2665 C C   . LEU B 2 70  ? -18.128 -15.862 21.373  1   43.17  ? 66  LEU A C   1 
ATOM   2666 O O   . LEU B 2 70  ? -19.148 -15.595 20.763  1   44.17  ? 66  LEU A O   1 
ATOM   2667 C CB  . LEU B 2 70  ? -16.654 -15.375 19.41   1   39.93  ? 66  LEU A CB  1 
ATOM   2668 C CG  . LEU B 2 70  ? -16.257 -13.943 19.79   1   40.85  ? 66  LEU A CG  1 
ATOM   2669 C CD1 . LEU B 2 70  ? -15.049 -13.928 20.733  1   40.77  ? 66  LEU A CD1 1 
ATOM   2670 C CD2 . LEU B 2 70  ? -15.938 -13.111 18.553  1   39.87  ? 66  LEU A CD2 1 
ATOM   2671 N N   . LEU B 2 71  ? -18.012 -15.759 22.702  1   43.85  ? 67  LEU A N   1 
ATOM   2672 C CA  . LEU B 2 71  ? -19.103 -15.428 23.61   1   44.21  ? 67  LEU A CA  1 
ATOM   2673 C C   . LEU B 2 71  ? -19.328 -13.93  23.717  1   46.1   ? 67  LEU A C   1 
ATOM   2674 O O   . LEU B 2 71  ? -20.453 -13.507 23.992  1   47.86  ? 67  LEU A O   1 
ATOM   2675 C CB  . LEU B 2 71  ? -18.88  -16.022 25      1   44.6   ? 67  LEU A CB  1 
ATOM   2676 C CG  . LEU B 2 71  ? -18.594 -17.528 24.999  1   45.66  ? 67  LEU A CG  1 
ATOM   2677 C CD1 . LEU B 2 71  ? -18.129 -18.023 26.375  1   45.83  ? 67  LEU A CD1 1 
ATOM   2678 C CD2 . LEU B 2 71  ? -19.841 -18.29  24.523  1   45.97  ? 67  LEU A CD2 1 
ATOM   2679 N N   . ASP B 2 72  ? -18.263 -13.132 23.556  1   47     ? 68  ASP A N   1 
ATOM   2680 C CA  . ASP B 2 72  ? -18.284 -11.729 23.963  1   48.56  ? 68  ASP A CA  1 
ATOM   2681 C C   . ASP B 2 72  ? -16.963 -11.077 23.562  1   48.75  ? 68  ASP A C   1 
ATOM   2682 O O   . ASP B 2 72  ? -15.963 -11.757 23.283  1   46.93  ? 68  ASP A O   1 
ATOM   2683 C CB  . ASP B 2 72  ? -18.477 -11.58  25.468  1   50.24  ? 68  ASP A CB  1 
ATOM   2684 C CG  . ASP B 2 72  ? -19.135 -10.289 25.944  1   54.64  ? 68  ASP A CG  1 
ATOM   2685 O OD1 . ASP B 2 72  ? -19.22  -9.304  25.165  1   54.49  ? 68  ASP A OD1 1 
ATOM   2686 O OD2 . ASP B 2 72  ? -19.598 -10.283 27.109  1   58.25  ? 68  ASP A OD2 1 
ATOM   2687 N N   . VAL B 2 73  ? -16.989 -9.747  23.489  1   49.16  ? 69  VAL A N   1 
ATOM   2688 C CA  . VAL B 2 73  ? -15.76  -8.961  23.192  1   50.15  ? 69  VAL A CA  1 
ATOM   2689 C C   . VAL B 2 73  ? -15.763 -7.76   24.151  1   54.13  ? 69  VAL A C   1 
ATOM   2690 O O   . VAL B 2 73  ? -16.774 -7.045  24.186  1   56.49  ? 69  VAL A O   1 
ATOM   2691 C CB  . VAL B 2 73  ? -15.668 -8.533  21.716  1   48.56  ? 69  VAL A CB  1 
ATOM   2692 C CG1 . VAL B 2 73  ? -14.795 -7.302  21.526  1   49.87  ? 69  VAL A CG1 1 
ATOM   2693 C CG2 . VAL B 2 73  ? -15.187 -9.669  20.825  1   45.14  ? 69  VAL A CG2 1 
ATOM   2694 N N   . ILE B 2 74  ? -14.703 -7.598  24.942  1   57.34  ? 70  ILE A N   1 
ATOM   2695 C CA  . ILE B 2 74  ? -14.583 -6.444  25.883  1   61.89  ? 70  ILE A CA  1 
ATOM   2696 C C   . ILE B 2 74  ? -13.619 -5.426  25.262  1   65.24  ? 70  ILE A C   1 
ATOM   2697 O O   . ILE B 2 74  ? -12.489 -5.816  24.946  1   62.64  ? 70  ILE A O   1 
ATOM   2698 C CB  . ILE B 2 74  ? -14.172 -6.902  27.295  1   62.82  ? 70  ILE A CB  1 
ATOM   2699 C CG1 . ILE B 2 74  ? -15.377 -7.404  28.086  1   61.83  ? 70  ILE A CG1 1 
ATOM   2700 C CG2 . ILE B 2 74  ? -13.435 -5.794  28.046  1   65.94  ? 70  ILE A CG2 1 
ATOM   2701 C CD1 . ILE B 2 74  ? -15.365 -8.896  28.355  1   61.02  ? 70  ILE A CD1 1 
ATOM   2702 N N   . HIS B 2 75  ? -14.094 -4.201  25.048  1   76.49  ? 71  HIS A N   1 
ATOM   2703 C CA  . HIS B 2 75  ? -13.327 -3.157  24.331  1   85.91  ? 71  HIS A CA  1 
ATOM   2704 C C   . HIS B 2 75  ? -12.836 -2.089  25.3    1   88.89  ? 71  HIS A C   1 
ATOM   2705 O O   . HIS B 2 75  ? -13.18  -0.914  25.102  1   93.63  ? 71  HIS A O   1 
ATOM   2706 C CB  . HIS B 2 75  ? -14.294 -2.432  23.394  1   95.26  ? 71  HIS A CB  1 
ATOM   2707 C CG  . HIS B 2 75  ? -13.923 -2.256  21.96   1   108.98 ? 71  HIS A CG  1 
ATOM   2708 N ND1 . HIS B 2 75  ? -12.795 -2.758  21.354  1   116.78 ? 71  HIS A ND1 1 
ATOM   2709 C CD2 . HIS B 2 75  ? -14.588 -1.59   21.007  1   114.9  ? 71  HIS A CD2 1 
ATOM   2710 C CE1 . HIS B 2 75  ? -12.794 -2.405  20.077  1   112.2  ? 71  HIS A CE1 1 
ATOM   2711 N NE2 . HIS B 2 75  ? -13.871 -1.689  19.847  1   111.29 ? 71  HIS A NE2 1 
ATOM   2712 N N   . THR B 2 76  ? -12.041 -2.469  26.298  1   93.1   ? 72  THR A N   1 
ATOM   2713 C CA  . THR B 2 76  ? -11.467 -1.474  27.233  1   103.24 ? 72  THR A CA  1 
ATOM   2714 C C   . THR B 2 76  ? -10.683 -0.427  26.462  1   113.94 ? 72  THR A C   1 
ATOM   2715 O O   . THR B 2 76  ? -10.304 -0.682  25.295  1   109.35 ? 72  THR A O   1 
ATOM   2716 C CB  . THR B 2 76  ? -10.601 -2.164  28.283  1   98.51  ? 72  THR A CB  1 
ATOM   2717 O OG1 . THR B 2 76  ? -9.59   -2.847  27.554  1   93.28  ? 72  THR A OG1 1 
ATOM   2718 C CG2 . THR B 2 76  ? -11.382 -3.177  29.098  1   94.48  ? 72  THR A CG2 1 
ATOM   2719 N N   . GLU B 2 77  ? -10.408 0.711   27.096  1   120.41 ? 73  GLU A N   1 
ATOM   2720 C CA  . GLU B 2 77  ? -9.705  1.823   26.405  1   122.08 ? 73  GLU A CA  1 
ATOM   2721 C C   . GLU B 2 77  ? -8.515  1.306   25.585  1   118.72 ? 73  GLU A C   1 
ATOM   2722 O O   . GLU B 2 77  ? -8.48   1.581   24.367  1   116.55 ? 73  GLU A O   1 
ATOM   2723 C CB  . GLU B 2 77  ? -9.249  2.857   27.432  1   125.14 ? 73  GLU A CB  1 
ATOM   2724 C CG  . GLU B 2 77  ? -8.579  4.076   26.804  1   128.6  ? 73  GLU A CG  1 
ATOM   2725 C CD  . GLU B 2 77  ? -8.165  5.131   27.811  1   136    ? 73  GLU A CD  1 
ATOM   2726 O OE1 . GLU B 2 77  ? -8.363  4.908   29.023  1   139.09 ? 73  GLU A OE1 1 
ATOM   2727 O OE2 . GLU B 2 77  ? -7.643  6.177   27.376  1   140.71 ? 73  GLU A OE2 1 
ATOM   2728 N N   . ASN B 2 78  ? -7.566  0.617   26.223  1   111.34 ? 74  ASN A N   1 
ATOM   2729 C CA  . ASN B 2 78  ? -6.345  0.192   25.482  1   106.06 ? 74  ASN A CA  1 
ATOM   2730 C C   . ASN B 2 78  ? -6.237  -1.331  25.475  1   97.41  ? 74  ASN A C   1 
ATOM   2731 O O   . ASN B 2 78  ? -5.105  -1.842  25.383  1   99.33  ? 74  ASN A O   1 
ATOM   2732 C CB  . ASN B 2 78  ? -5.083  0.818   26.062  1   112.79 ? 74  ASN A CB  1 
ATOM   2733 C CG  . ASN B 2 78  ? -5.304  2.24    26.512  1   118.18 ? 74  ASN A CG  1 
ATOM   2734 O OD1 . ASN B 2 78  ? -5.524  2.489   27.702  1   118.96 ? 74  ASN A OD1 1 
ATOM   2735 N ND2 . ASN B 2 78  ? -5.254  3.182   25.582  1   120.38 ? 74  ASN A ND2 1 
ATOM   2736 N N   . LYS B 2 79  ? -7.372  -2.023  25.55   1   91.33  ? 75  LYS A N   1 
ATOM   2737 C CA  . LYS B 2 79  ? -7.317  -3.502  25.624  1   83.68  ? 75  LYS A CA  1 
ATOM   2738 C C   . LYS B 2 79  ? -8.534  -4.143  24.946  1   73.73  ? 75  LYS A C   1 
ATOM   2739 O O   . LYS B 2 79  ? -9.65   -3.627  25.106  1   71.41  ? 75  LYS A O   1 
ATOM   2740 C CB  . LYS B 2 79  ? -7.187  -3.935  27.086  1   88.71  ? 75  LYS A CB  1 
ATOM   2741 C CG  . LYS B 2 79  ? -5.867  -3.547  27.732  1   93.13  ? 75  LYS A CG  1 
ATOM   2742 C CD  . LYS B 2 79  ? -5.773  -3.968  29.192  1   93.99  ? 75  LYS A CD  1 
ATOM   2743 C CE  . LYS B 2 79  ? -4.456  -3.595  29.792  1   96     ? 75  LYS A CE  1 
ATOM   2744 N NZ  . LYS B 2 79  ? -4.372  -3.978  31.204  1   91.8   ? 75  LYS A NZ  1 
ATOM   2745 N N   . LEU B 2 80  ? -8.299  -5.219  24.204  1   65.1   ? 76  LEU A N   1 
ATOM   2746 C CA  . LEU B 2 80  ? -9.399  -5.976  23.569  1   60.47  ? 76  LEU A CA  1 
ATOM   2747 C C   . LEU B 2 80  ? -9.362  -7.398  24.126  1   58.92  ? 76  LEU A C   1 
ATOM   2748 O O   . LEU B 2 80  ? -8.312  -8.042  24.029  1   58.14  ? 76  LEU A O   1 
ATOM   2749 C CB  . LEU B 2 80  ? -9.209  -5.936  22.058  1   59.39  ? 76  LEU A CB  1 
ATOM   2750 C CG  . LEU B 2 80  ? -10.421 -6.282  21.192  1   55.97  ? 76  LEU A CG  1 
ATOM   2751 C CD1 . LEU B 2 80  ? -11.673 -5.701  21.798  1   58.44  ? 76  LEU A CD1 1 
ATOM   2752 C CD2 . LEU B 2 80  ? -10.198 -5.719  19.804  1   54.42  ? 76  LEU A CD2 1 
ATOM   2753 N N   . TYR B 2 81  ? -10.466 -7.843  24.716  1   59.65  ? 77  TYR A N   1 
ATOM   2754 C CA  . TYR B 2 81  ? -10.543 -9.212  25.284  1   57.54  ? 77  TYR A CA  1 
ATOM   2755 C C   . TYR B 2 81  ? -11.574 -10.01  24.517  1   54.49  ? 77  TYR A C   1 
ATOM   2756 O O   . TYR B 2 81  ? -12.731 -9.587  24.413  1   56.65  ? 77  TYR A O   1 
ATOM   2757 C CB  . TYR B 2 81  ? -10.923 -9.168  26.763  1   59.21  ? 77  TYR A CB  1 
ATOM   2758 C CG  . TYR B 2 81  ? -9.813  -8.744  27.71   1   64.6   ? 77  TYR A CG  1 
ATOM   2759 C CD1 . TYR B 2 81  ? -8.793  -9.618  28.059  1   66.13  ? 77  TYR A CD1 1 
ATOM   2760 C CD2 . TYR B 2 81  ? -9.795  -7.47   28.26   1   68.75  ? 77  TYR A CD2 1 
ATOM   2761 C CE1 . TYR B 2 81  ? -7.786  -9.235  28.928  1   70     ? 77  TYR A CE1 1 
ATOM   2762 C CE2 . TYR B 2 81  ? -8.796  -7.077  29.132  1   73     ? 77  TYR A CE2 1 
ATOM   2763 C CZ  . TYR B 2 81  ? -7.787  -7.961  29.464  1   74.3   ? 77  TYR A CZ  1 
ATOM   2764 O OH  . TYR B 2 81  ? -6.802  -7.565  30.319  1   81.03  ? 77  TYR A OH  1 
ATOM   2765 N N   . LEU B 2 82  ? -11.158 -11.153 23.987  1   49.76  ? 78  LEU A N   1 
ATOM   2766 C CA  . LEU B 2 82  ? -12.104 -12.039 23.276  1   47.17  ? 78  LEU A CA  1 
ATOM   2767 C C   . LEU B 2 82  ? -12.467 -13.188 24.22   1   49.48  ? 78  LEU A C   1 
ATOM   2768 O O   . LEU B 2 82  ? -11.567 -13.955 24.572  1   51.64  ? 78  LEU A O   1 
ATOM   2769 C CB  . LEU B 2 82  ? -11.462 -12.527 21.98   1   43.23  ? 78  LEU A CB  1 
ATOM   2770 C CG  . LEU B 2 82  ? -11.58  -11.609 20.761  1   41.9   ? 78  LEU A CG  1 
ATOM   2771 C CD1 . LEU B 2 82  ? -10.708 -10.378 20.89   1   43.04  ? 78  LEU A CD1 1 
ATOM   2772 C CD2 . LEU B 2 82  ? -11.216 -12.373 19.507  1   39.57  ? 78  LEU A CD2 1 
ATOM   2773 N N   . VAL B 2 83  ? -13.732 -13.267 24.637  1   48.69  ? 79  VAL A N   1 
ATOM   2774 C CA  . VAL B 2 83  ? -14.157 -14.347 25.517  1   46.85  ? 79  VAL A CA  1 
ATOM   2775 C C   . VAL B 2 83  ? -14.635 -15.513 24.66   1   45.35  ? 79  VAL A C   1 
ATOM   2776 O O   . VAL B 2 83  ? -15.541 -15.357 23.856  1   44.85  ? 79  VAL A O   1 
ATOM   2777 C CB  . VAL B 2 83  ? -15.281 -13.865 26.438  1   46.77  ? 79  VAL A CB  1 
ATOM   2778 C CG1 . VAL B 2 83  ? -15.545 -14.849 27.566  1   46.54  ? 79  VAL A CG1 1 
ATOM   2779 C CG2 . VAL B 2 83  ? -14.968 -12.479 26.954  1   48.12  ? 79  VAL A CG2 1 
ATOM   2780 N N   . PHE B 2 84  ? -14.015 -16.681 24.847  1   44.8   ? 80  PHE A N   1 
ATOM   2781 C CA  . PHE B 2 84  ? -14.364 -17.861 24.014  1   43.36  ? 80  PHE A CA  1 
ATOM   2782 C C   . PHE B 2 84  ? -14.802 -19.015 24.889  1   43.69  ? 80  PHE A C   1 
ATOM   2783 O O   . PHE B 2 84  ? -14.465 -19.024 26.09   1   44.77  ? 80  PHE A O   1 
ATOM   2784 C CB  . PHE B 2 84  ? -13.131 -18.366 23.267  1   42.27  ? 80  PHE A CB  1 
ATOM   2785 C CG  . PHE B 2 84  ? -12.657 -17.504 22.108  1   42.48  ? 80  PHE A CG  1 
ATOM   2786 C CD1 . PHE B 2 84  ? -13.37  -17.461 20.917  1   41.82  ? 80  PHE A CD1 1 
ATOM   2787 C CD2 . PHE B 2 84  ? -11.49  -16.756 22.207  1   43.1   ? 80  PHE A CD2 1 
ATOM   2788 C CE1 . PHE B 2 84  ? -12.93  -16.683 19.861  1   40.07  ? 80  PHE A CE1 1 
ATOM   2789 C CE2 . PHE B 2 84  ? -11.054 -15.983 21.145  1   42.22  ? 80  PHE A CE2 1 
ATOM   2790 C CZ  . PHE B 2 84  ? -11.776 -15.946 19.975  1   40.24  ? 80  PHE A CZ  1 
ATOM   2791 N N   . GLU B 2 85  ? -15.517 -19.983 24.307  1   43.66  ? 81  GLU A N   1 
ATOM   2792 C CA  . GLU B 2 85  ? -15.864 -21.205 25.077  1   44.46  ? 81  GLU A CA  1 
ATOM   2793 C C   . GLU B 2 85  ? -14.539 -21.896 25.431  1   44.07  ? 81  GLU A C   1 
ATOM   2794 O O   . GLU B 2 85  ? -13.593 -21.821 24.613  1   43.38  ? 81  GLU A O   1 
ATOM   2795 C CB  . GLU B 2 85  ? -16.778 -22.114 24.258  1   46.26  ? 81  GLU A CB  1 
ATOM   2796 C CG  . GLU B 2 85  ? -16.222 -22.416 22.87   1   51.08  ? 81  GLU A CG  1 
ATOM   2797 C CD  . GLU B 2 85  ? -16.746 -23.692 22.241  1   50.14  ? 81  GLU A CD  1 
ATOM   2798 O OE1 . GLU B 2 85  ? -16.699 -24.742 22.913  1   49.14  ? 81  GLU A OE1 1 
ATOM   2799 O OE2 . GLU B 2 85  ? -17.2   -23.633 21.079  1   49.27  ? 81  GLU A OE2 1 
ATOM   2800 N N   . PHE B 2 86  ? -14.411 -22.485 26.611  1   44.45  ? 82  PHE A N   1 
ATOM   2801 C CA  . PHE B 2 86  ? -13.098 -23.077 26.967  1   44.71  ? 82  PHE A CA  1 
ATOM   2802 C C   . PHE B 2 86  ? -13.019 -24.52  26.494  1   45.03  ? 82  PHE A C   1 
ATOM   2803 O O   . PHE B 2 86  ? -13.931 -25.31  26.773  1   47.24  ? 82  PHE A O   1 
ATOM   2804 C CB  . PHE B 2 86  ? -12.781 -23.052 28.462  1   46.36  ? 82  PHE A CB  1 
ATOM   2805 C CG  . PHE B 2 86  ? -11.487 -23.754 28.844  1   46.6   ? 82  PHE A CG  1 
ATOM   2806 C CD1 . PHE B 2 86  ? -10.258 -23.167 28.585  1   46.18  ? 82  PHE A CD1 1 
ATOM   2807 C CD2 . PHE B 2 86  ? -11.506 -25.003 29.452  1   46.2   ? 82  PHE A CD2 1 
ATOM   2808 C CE1 . PHE B 2 86  ? -9.083  -23.812 28.927  1   47.13  ? 82  PHE A CE1 1 
ATOM   2809 C CE2 . PHE B 2 86  ? -10.328 -25.641 29.79   1   47.86  ? 82  PHE A CE2 1 
ATOM   2810 C CZ  . PHE B 2 86  ? -9.12   -25.044 29.528  1   47.38  ? 82  PHE A CZ  1 
ATOM   2811 N N   . LEU B 2 87  ? -11.946 -24.85  25.788  1   44.23  ? 83  LEU A N   1 
ATOM   2812 C CA  . LEU B 2 87  ? -11.7   -26.251 25.381  1   44.56  ? 83  LEU A CA  1 
ATOM   2813 C C   . LEU B 2 87  ? -10.372 -26.643 26.035  1   46.34  ? 83  LEU A C   1 
ATOM   2814 O O   . LEU B 2 87  ? -9.437  -25.833 25.975  1   47.21  ? 83  LEU A O   1 
ATOM   2815 C CB  . LEU B 2 87  ? -11.725 -26.386 23.862  1   43.46  ? 83  LEU A CB  1 
ATOM   2816 C CG  . LEU B 2 87  ? -13.112 -26.309 23.219  1   45.77  ? 83  LEU A CG  1 
ATOM   2817 C CD1 . LEU B 2 87  ? -13.212 -25.094 22.323  1   44.85  ? 83  LEU A CD1 1 
ATOM   2818 C CD2 . LEU B 2 87  ? -13.412 -27.575 22.449  1   44.78  ? 83  LEU A CD2 1 
ATOM   2819 N N   . HIS B 2 88  ? -10.29  -27.833 26.62   1   45.51  ? 84  HIS A N   1 
ATOM   2820 C CA  . HIS B 2 88  ? -9.11   -28.215 27.445  1   45.86  ? 84  HIS A CA  1 
ATOM   2821 C C   . HIS B 2 88  ? -7.805  -28.424 26.671  1   46.47  ? 84  HIS A C   1 
ATOM   2822 O O   . HIS B 2 88  ? -6.748  -28.168 27.261  1   46.76  ? 84  HIS A O   1 
ATOM   2823 C CB  . HIS B 2 88  ? -9.47   -29.431 28.305  1   45.01  ? 84  HIS A CB  1 
ATOM   2824 C CG  . HIS B 2 88  ? -9.282  -30.771 27.68   1   42.94  ? 84  HIS A CG  1 
ATOM   2825 N ND1 . HIS B 2 88  ? -8.268  -31.626 28.049  1   43.62  ? 84  HIS A ND1 1 
ATOM   2826 C CD2 . HIS B 2 88  ? -9.987  -31.419 26.751  1   41.3   ? 84  HIS A CD2 1 
ATOM   2827 C CE1 . HIS B 2 88  ? -8.36   -32.743 27.346  1   42.72  ? 84  HIS A CE1 1 
ATOM   2828 N NE2 . HIS B 2 88  ? -9.398  -32.637 26.55   1   41.13  ? 84  HIS A NE2 1 
ATOM   2829 N N   . GLN B 2 89  ? -7.857  -28.855 25.417  1   45.59  ? 85  GLN A N   1 
ATOM   2830 C CA  . GLN B 2 89  ? -6.579  -29.18  24.746  1   47.18  ? 85  GLN A CA  1 
ATOM   2831 C C   . GLN B 2 89  ? -6.634  -28.982 23.239  1   45.87  ? 85  GLN A C   1 
ATOM   2832 O O   . GLN B 2 89  ? -7.729  -28.843 22.69   1   45.22  ? 85  GLN A O   1 
ATOM   2833 C CB  . GLN B 2 89  ? -6.262  -30.656 24.964  1   50.9   ? 85  GLN A CB  1 
ATOM   2834 C CG  . GLN B 2 89  ? -4.781  -30.998 25.05   1   53.3   ? 85  GLN A CG  1 
ATOM   2835 C CD  . GLN B 2 89  ? -4.545  -32.485 25.166  1   59.93  ? 85  GLN A CD  1 
ATOM   2836 O OE1 . GLN B 2 89  ? -3.413  -32.952 25.313  1   70.15  ? 85  GLN A OE1 1 
ATOM   2837 N NE2 . GLN B 2 89  ? -5.624  -33.249 25.107  1   64.57  ? 85  GLN A NE2 1 
ATOM   2838 N N   . ASP B 2 90  ? -5.463  -28.953 22.62   1   42.78  ? 86  ASP A N   1 
ATOM   2839 C CA  . ASP B 2 90  ? -5.395  -28.889 21.17   1   42.26  ? 86  ASP A CA  1 
ATOM   2840 C C   . ASP B 2 90  ? -4.949  -30.254 20.636  1   41     ? 86  ASP A C   1 
ATOM   2841 O O   . ASP B 2 90  ? -4.345  -31.054 21.352  1   40.26  ? 86  ASP A O   1 
ATOM   2842 C CB  . ASP B 2 90  ? -4.544  -27.73  20.677  1   44.66  ? 86  ASP A CB  1 
ATOM   2843 C CG  . ASP B 2 90  ? -3.044  -27.96  20.824  1   45.82  ? 86  ASP A CG  1 
ATOM   2844 O OD1 . ASP B 2 90  ? -2.513  -28.863 20.174  1   46.53  ? 86  ASP A OD1 1 
ATOM   2845 O OD2 . ASP B 2 90  ? -2.432  -27.276 21.621  1   52.16  ? 86  ASP A OD2 1 
ATOM   2846 N N   . LEU B 2 91  ? -5.271  -30.491 19.367  1   38.7   ? 87  LEU A N   1 
ATOM   2847 C CA  . LEU B 2 91  ? -5.063  -31.782 18.75   1   41.26  ? 87  LEU A CA  1 
ATOM   2848 C C   . LEU B 2 91  ? -3.576  -32.126 18.702  1   42.27  ? 87  LEU A C   1 
ATOM   2849 O O   . LEU B 2 91  ? -3.231  -33.3   18.732  1   46.23  ? 87  LEU A O   1 
ATOM   2850 C CB  . LEU B 2 91  ? -5.668  -31.816 17.349  1   39.73  ? 87  LEU A CB  1 
ATOM   2851 C CG  . LEU B 2 91  ? -5.504  -33.139 16.59   1   39.3   ? 87  LEU A CG  1 
ATOM   2852 C CD1 . LEU B 2 91  ? -6.252  -34.263 17.279  1   38.51  ? 87  LEU A CD1 1 
ATOM   2853 C CD2 . LEU B 2 91  ? -5.972  -32.978 15.151  1   38.88  ? 87  LEU A CD2 1 
ATOM   2854 N N   . LYS B 2 92  ? -2.708  -31.123 18.593  1   43.34  ? 88  LYS A N   1 
ATOM   2855 C CA  . LYS B 2 92  ? -1.281  -31.403 18.554  1   46.12  ? 88  LYS A CA  1 
ATOM   2856 C C   . LYS B 2 92  ? -0.839  -31.95  19.911  1   46.4   ? 88  LYS A C   1 
ATOM   2857 O O   . LYS B 2 92  ? -0.258  -33.038 19.966  1   46.91  ? 88  LYS A O   1 
ATOM   2858 C CB  . LYS B 2 92  ? -0.52   -30.184 18.044  1   49.22  ? 88  LYS A CB  1 
ATOM   2859 C CG  . LYS B 2 92  ? 0.959   -30.085 18.419  1   53.74  ? 88  LYS A CG  1 
ATOM   2860 C CD  . LYS B 2 92  ? 1.852   -31.27  18.073  1   62.13  ? 88  LYS A CD  1 
ATOM   2861 C CE  . LYS B 2 92  ? 1.907   -31.661 16.62   1   66.23  ? 88  LYS A CE  1 
ATOM   2862 N NZ  . LYS B 2 92  ? 3.125   -32.469 16.454  1   64.67  ? 88  LYS A NZ  1 
ATOM   2863 N N   . LYS B 2 93  ? -1.2    -31.264 21.007  1   47.92  ? 89  LYS A N   1 
ATOM   2864 C CA  . LYS B 2 93  ? -0.868  -31.761 22.335  1   53.24  ? 89  LYS A CA  1 
ATOM   2865 C C   . LYS B 2 93  ? -1.418  -33.176 22.54   1   52.64  ? 89  LYS A C   1 
ATOM   2866 O O   . LYS B 2 93  ? -0.745  -34.024 23.132  1   53.41  ? 89  LYS A O   1 
ATOM   2867 C CB  . LYS B 2 93  ? -1.214  -30.761 23.44   1   61.88  ? 89  LYS A CB  1 
ATOM   2868 C CG  . LYS B 2 93  ? -0.162  -29.654 23.561  1   79.93  ? 89  LYS A CG  1 
ATOM   2869 C CD  . LYS B 2 93  ? -0.571  -28.35  24.244  1   97.16  ? 89  LYS A CD  1 
ATOM   2870 C CE  . LYS B 2 93  ? 0.388   -27.221 23.956  1   104.48 ? 89  LYS A CE  1 
ATOM   2871 N NZ  . LYS B 2 93  ? 0.082   -25.967 24.656  1   113.29 ? 89  LYS A NZ  1 
ATOM   2872 N N   . PHE B 2 94  ? -2.62   -33.444 22.016  1   47.02  ? 90  PHE A N   1 
ATOM   2873 C CA  . PHE B 2 94  ? -3.263  -34.72  22.27   1   47.74  ? 90  PHE A CA  1 
ATOM   2874 C C   . PHE B 2 94  ? -2.507  -35.827 21.554  1   46.36  ? 90  PHE A C   1 
ATOM   2875 O O   . PHE B 2 94  ? -2.309  -36.897 22.122  1   47.45  ? 90  PHE A O   1 
ATOM   2876 C CB  . PHE B 2 94  ? -4.742  -34.706 21.848  1   47.01  ? 90  PHE A CB  1 
ATOM   2877 C CG  . PHE B 2 94  ? -5.456  -36.04  21.983  1   45.66  ? 90  PHE A CG  1 
ATOM   2878 C CD1 . PHE B 2 94  ? -5.742  -36.565 23.232  1   49.19  ? 90  PHE A CD1 1 
ATOM   2879 C CD2 . PHE B 2 94  ? -5.839  -36.76  20.861  1   45.99  ? 90  PHE A CD2 1 
ATOM   2880 C CE1 . PHE B 2 94  ? -6.444  -37.759 23.347  1   51.21  ? 90  PHE A CE1 1 
ATOM   2881 C CE2 . PHE B 2 94  ? -6.53   -37.959 20.987  1   48.88  ? 90  PHE A CE2 1 
ATOM   2882 C CZ  . PHE B 2 94  ? -6.811  -38.47  22.231  1   48.46  ? 90  PHE A CZ  1 
ATOM   2883 N N   . MET B 2 95  ? -2.151  -35.579 20.291  1   45.93  ? 91  MET A N   1 
ATOM   2884 C CA  . MET B 2 95  ? -1.316  -36.507 19.546  1   49.8   ? 91  MET A CA  1 
ATOM   2885 C C   . MET B 2 95  ? 0.035   -36.722 20.229  1   56.61  ? 91  MET A C   1 
ATOM   2886 O O   . MET B 2 95  ? 0.466   -37.859 20.35   1   63.23  ? 91  MET A O   1 
ATOM   2887 C CB  . MET B 2 95  ? -1.109  -36.007 18.125  1   49.35  ? 91  MET A CB  1 
ATOM   2888 C CG  . MET B 2 95  ? -2.267  -36.381 17.25   1   49.92  ? 91  MET A CG  1 
ATOM   2889 S SD  . MET B 2 95  ? -2.117  -35.641 15.618  1   57.94  ? 91  MET A SD  1 
ATOM   2890 C CE  . MET B 2 95  ? -1.499  -33.981 15.904  1   48.6   ? 91  MET A CE  1 
ATOM   2891 N N   . ASP B 2 96  ? 0.679   -35.659 20.73   1   56.55  ? 92  ASP A N   1 
ATOM   2892 C CA  . ASP B 2 96  ? 2.003   -35.823 21.312  1   61.11  ? 92  ASP A CA  1 
ATOM   2893 C C   . ASP B 2 96  ? 1.94    -36.632 22.591  1   67.91  ? 92  ASP A C   1 
ATOM   2894 O O   . ASP B 2 96  ? 2.443   -37.746 22.64   1   68.97  ? 92  ASP A O   1 
ATOM   2895 C CB  . ASP B 2 96  ? 2.675   -34.498 21.615  1   59.62  ? 92  ASP A CB  1 
ATOM   2896 C CG  . ASP B 2 96  ? 3.178   -33.846 20.349  1   60.01  ? 92  ASP A CG  1 
ATOM   2897 O OD1 . ASP B 2 96  ? 3.252   -34.581 19.318  1   57.48  ? 92  ASP A OD1 1 
ATOM   2898 O OD2 . ASP B 2 96  ? 3.405   -32.621 20.404  1   63.38  ? 92  ASP A OD2 1 
ATOM   2899 N N   . ALA B 2 97  ? 1.368   -36.015 23.626  1   79.24  ? 93  ALA A N   1 
ATOM   2900 C CA  . ALA B 2 97  ? 1.271   -36.628 24.941  1   84.56  ? 93  ALA A CA  1 
ATOM   2901 C C   . ALA B 2 97  ? -0.09   -37.306 24.984  1   82.09  ? 93  ALA A C   1 
ATOM   2902 O O   . ALA B 2 97  ? -1.09   -36.667 24.663  1   86.28  ? 93  ALA A O   1 
ATOM   2903 C CB  . ALA B 2 97  ? 1.442   -35.569 26.019  1   84.71  ? 93  ALA A CB  1 
ATOM   2904 N N   . SER B 2 98  ? -0.116  -38.602 25.314  1   78.67  ? 94  SER A N   1 
ATOM   2905 C CA  . SER B 2 98  ? -1.293  -39.395 24.994  1   83.97  ? 94  SER A CA  1 
ATOM   2906 C C   . SER B 2 98  ? -1.221  -39.667 23.493  1   81.17  ? 94  SER A C   1 
ATOM   2907 O O   . SER B 2 98  ? -0.518  -38.961 22.766  1   80.74  ? 94  SER A O   1 
ATOM   2908 C CB  . SER B 2 98  ? -2.603  -38.674 25.417  1   82.49  ? 94  SER A CB  1 
ATOM   2909 O OG  . SER B 2 98  ? -3.706  -39.537 25.688  1   82.14  ? 94  SER A OG  1 
ATOM   2910 N N   . ALA B 2 99  ? -1.918  -40.705 23.032  1   80.57  ? 95  ALA A N   1 
ATOM   2911 C CA  . ALA B 2 99  ? -1.765  -41.142 21.653  1   73.84  ? 95  ALA A CA  1 
ATOM   2912 C C   . ALA B 2 99  ? -0.299  -41.514 21.426  1   79.87  ? 95  ALA A C   1 
ATOM   2913 O O   . ALA B 2 99  ? 0.348   -41.022 20.518  1   85.34  ? 95  ALA A O   1 
ATOM   2914 C CB  . ALA B 2 99  ? -2.296  -40.101 20.697  1   57.04  ? 95  ALA A CB  1 
ATOM   2915 N N   . LEU B 2 100 ? 0.23    -42.373 22.305  1   94.02  ? 96  LEU A N   1 
ATOM   2916 C CA  . LEU B 2 100 ? 1.598   -42.849 22.184  1   98.16  ? 96  LEU A CA  1 
ATOM   2917 C C   . LEU B 2 100 ? 1.628   -44.105 21.322  1   95.49  ? 96  LEU A C   1 
ATOM   2918 O O   . LEU B 2 100 ? 2.559   -44.3   20.546  1   89.35  ? 96  LEU A O   1 
ATOM   2919 C CB  . LEU B 2 100 ? 2.181   -43.115 23.571  1   109.48 ? 96  LEU A CB  1 
ATOM   2920 C CG  . LEU B 2 100 ? 2.51    -41.88  24.419  1   118.54 ? 96  LEU A CG  1 
ATOM   2921 C CD1 . LEU B 2 100 ? 2.79    -40.654 23.553  1   112.61 ? 96  LEU A CD1 1 
ATOM   2922 C CD2 . LEU B 2 100 ? 1.476   -41.588 25.489  1   114.21 ? 96  LEU A CD2 1 
ATOM   2923 N N   . THR B 2 101 ? 0.607   -44.957 21.499  1   97.1   ? 97  THR A N   1 
ATOM   2924 C CA  . THR B 2 101 ? 0.37    -46.112 20.646  1   91.07  ? 97  THR A CA  1 
ATOM   2925 C C   . THR B 2 101 ? -0.809  -45.843 19.704  1   86.38  ? 97  THR A C   1 
ATOM   2926 O O   . THR B 2 101 ? -1.43   -46.775 19.194  1   89.21  ? 97  THR A O   1 
ATOM   2927 C CB  . THR B 2 101 ? 0.151   -47.37  21.487  1   95.2   ? 97  THR A CB  1 
ATOM   2928 O OG1 . THR B 2 101 ? -1.081  -47.159 22.178  1   106.99 ? 97  THR A OG1 1 
ATOM   2929 C CG2 . THR B 2 101 ? 1.338   -47.692 22.379  1   93.52  ? 97  THR A CG2 1 
ATOM   2930 N N   . GLY B 2 102 ? -1.125  -44.567 19.468  1   76.15  ? 98  GLY A N   1 
ATOM   2931 C CA  . GLY B 2 102 ? -2.003  -44.206 18.365  1   66.1   ? 98  GLY A CA  1 
ATOM   2932 C C   . GLY B 2 102 ? -3.302  -43.562 18.844  1   61.25  ? 98  GLY A C   1 
ATOM   2933 O O   . GLY B 2 102 ? -3.625  -43.617 20.026  1   64.63  ? 98  GLY A O   1 
ATOM   2934 N N   . ILE B 2 103 ? -4.02   -42.921 17.921  1   57.8   ? 99  ILE A N   1 
ATOM   2935 C CA  . ILE B 2 103 ? -5.41   -42.535 18.146  1   54.5   ? 99  ILE A CA  1 
ATOM   2936 C C   . ILE B 2 103 ? -6.294  -43.674 17.634  1   48.78  ? 99  ILE A C   1 
ATOM   2937 O O   . ILE B 2 103 ? -6.185  -44.067 16.486  1   48.37  ? 99  ILE A O   1 
ATOM   2938 C CB  . ILE B 2 103 ? -5.717  -41.218 17.413  1   53.85  ? 99  ILE A CB  1 
ATOM   2939 C CG1 . ILE B 2 103 ? -4.737  -40.112 17.793  1   54.63  ? 99  ILE A CG1 1 
ATOM   2940 C CG2 . ILE B 2 103 ? -7.17   -40.795 17.646  1   57.78  ? 99  ILE A CG2 1 
ATOM   2941 C CD1 . ILE B 2 103 ? -4.984  -38.805 17.057  1   52.6   ? 99  ILE A CD1 1 
ATOM   2942 N N   . PRO B 2 104 ? -7.213  -44.242 18.434  1   48.42  ? 100 PRO A N   1 
ATOM   2943 C CA  . PRO B 2 104 ? -8.097  -45.297 17.911  1   48.49  ? 100 PRO A CA  1 
ATOM   2944 C C   . PRO B 2 104 ? -8.882  -44.777 16.702  1   46.92  ? 100 PRO A C   1 
ATOM   2945 O O   . PRO B 2 104 ? -9.253  -43.601 16.654  1   46     ? 100 PRO A O   1 
ATOM   2946 C CB  . PRO B 2 104 ? -9.038  -45.612 19.091  1   52.69  ? 100 PRO A CB  1 
ATOM   2947 C CG  . PRO B 2 104 ? -8.455  -44.885 20.316  1   52.08  ? 100 PRO A CG  1 
ATOM   2948 C CD  . PRO B 2 104 ? -7.538  -43.793 19.8    1   48.82  ? 100 PRO A CD  1 
ATOM   2949 N N   . LEU B 2 105 ? -9.092  -45.644 15.706  1   47.62  ? 101 LEU A N   1 
ATOM   2950 C CA  . LEU B 2 105 ? -9.754  -45.333 14.436  1   47.77  ? 101 LEU A CA  1 
ATOM   2951 C C   . LEU B 2 105 ? -11.132 -44.69  14.669  1   48.49  ? 101 LEU A C   1 
ATOM   2952 O O   . LEU B 2 105 ? -11.452 -43.682 14.032  1   51.91  ? 101 LEU A O   1 
ATOM   2953 C CB  . LEU B 2 105 ? -9.948  -46.632 13.652  1   48.39  ? 101 LEU A CB  1 
ATOM   2954 C CG  . LEU B 2 105 ? -10.687 -46.561 12.316  1   48.23  ? 101 LEU A CG  1 
ATOM   2955 C CD1 . LEU B 2 105 ? -9.89   -45.693 11.346  1   54.11  ? 101 LEU A CD1 1 
ATOM   2956 C CD2 . LEU B 2 105 ? -11.068 -47.893 11.691  1   45.37  ? 101 LEU A CD2 1 
ATOM   2957 N N   . PRO B 2 106 ? -11.989 -45.223 15.571  1   46.2   ? 102 PRO A N   1 
ATOM   2958 C CA  . PRO B 2 106 ? -13.27  -44.584 15.878  1   46.83  ? 102 PRO A CA  1 
ATOM   2959 C C   . PRO B 2 106 ? -13.151 -43.095 16.161  1   47.78  ? 102 PRO A C   1 
ATOM   2960 O O   . PRO B 2 106 ? -13.973 -42.305 15.685  1   50.99  ? 102 PRO A O   1 
ATOM   2961 C CB  . PRO B 2 106 ? -13.816 -45.37  17.105  1   47.01  ? 102 PRO A CB  1 
ATOM   2962 C CG  . PRO B 2 106 ? -13.222 -46.752 16.93   1   48.46  ? 102 PRO A CG  1 
ATOM   2963 C CD  . PRO B 2 106 ? -11.834 -46.501 16.285  1   47.11  ? 102 PRO A CD  1 
ATOM   2964 N N   . LEU B 2 107 ? -12.12  -42.719 16.932  1   47.47  ? 103 LEU A N   1 
ATOM   2965 C CA  . LEU B 2 107 ? -11.917 -41.34  17.353  1   45.68  ? 103 LEU A CA  1 
ATOM   2966 C C   . LEU B 2 107 ? -11.357 -40.526 16.185  1   43.28  ? 103 LEU A C   1 
ATOM   2967 O O   . LEU B 2 107 ? -11.59  -39.327 16.067  1   44.63  ? 103 LEU A O   1 
ATOM   2968 C CB  . LEU B 2 107 ? -10.989 -41.368 18.566  1   44.86  ? 103 LEU A CB  1 
ATOM   2969 C CG  . LEU B 2 107 ? -10.849 -40.082 19.387  1   44.35  ? 103 LEU A CG  1 
ATOM   2970 C CD1 . LEU B 2 107 ? -12.235 -39.47  19.684  1   43.26  ? 103 LEU A CD1 1 
ATOM   2971 C CD2 . LEU B 2 107 ? -10.128 -40.441 20.72   1   43.41  ? 103 LEU A CD2 1 
ATOM   2972 N N   . ILE B 2 108 ? -10.632 -41.184 15.286  1   42.66  ? 104 ILE A N   1 
ATOM   2973 C CA  . ILE B 2 108 ? -10.075 -40.467 14.146  1   40.78  ? 104 ILE A CA  1 
ATOM   2974 C C   . ILE B 2 108 ? -11.227 -40.103 13.207  1   38.57  ? 104 ILE A C   1 
ATOM   2975 O O   . ILE B 2 108 ? -11.271 -38.986 12.666  1   35.69  ? 104 ILE A O   1 
ATOM   2976 C CB  . ILE B 2 108 ? -9.014  -41.326 13.424  1   38.37  ? 104 ILE A CB  1 
ATOM   2977 C CG1 . ILE B 2 108 ? -7.725  -41.495 14.29   1   38.9   ? 104 ILE A CG1 1 
ATOM   2978 C CG2 . ILE B 2 108 ? -8.713  -40.714 12.051  1   35.02  ? 104 ILE A CG2 1 
ATOM   2979 C CD1 . ILE B 2 108 ? -6.646  -42.352 13.636  1   36.02  ? 104 ILE A CD1 1 
ATOM   2980 N N   . LYS B 2 109 ? -12.108 -41.09  12.975  1   38.59  ? 105 LYS A N   1 
ATOM   2981 C CA  . LYS B 2 109 ? -13.305 -40.904 12.166  1   40.35  ? 105 LYS A CA  1 
ATOM   2982 C C   . LYS B 2 109 ? -14.141 -39.751 12.709  1   39.35  ? 105 LYS A C   1 
ATOM   2983 O O   . LYS B 2 109 ? -14.465 -38.823 11.955  1   38.22  ? 105 LYS A O   1 
ATOM   2984 C CB  . LYS B 2 109 ? -14.159 -42.174 12.101  1   41.15  ? 105 LYS A CB  1 
ATOM   2985 C CG  . LYS B 2 109 ? -13.76  -43.143 11.016  1   42.02  ? 105 LYS A CG  1 
ATOM   2986 C CD  . LYS B 2 109 ? -14.415 -44.503 11.164  1   45.28  ? 105 LYS A CD  1 
ATOM   2987 C CE  . LYS B 2 109 ? -13.833 -45.449 10.173  1   48.07  ? 105 LYS A CE  1 
ATOM   2988 N NZ  . LYS B 2 109 ? -14.462 -46.776 10.223  1   57.26  ? 105 LYS A NZ  1 
ATOM   2989 N N   . SER B 2 110 ? -14.461 -39.832 14.01   1   41.46  ? 106 SER A N   1 
ATOM   2990 C CA  . SER B 2 110 ? -15.34  -38.873 14.683  1   46.23  ? 106 SER A CA  1 
ATOM   2991 C C   . SER B 2 110 ? -14.797 -37.46  14.532  1   43.66  ? 106 SER A C   1 
ATOM   2992 O O   . SER B 2 110 ? -15.533 -36.554 14.145  1   43.04  ? 106 SER A O   1 
ATOM   2993 C CB  . SER B 2 110 ? -15.553 -39.222 16.141  1   48.63  ? 106 SER A CB  1 
ATOM   2994 O OG  . SER B 2 110 ? -16.094 -38.139 16.886  1   53.6   ? 106 SER A OG  1 
ATOM   2995 N N   . TYR B 2 111 ? -13.49  -37.32  14.765  1   41.44  ? 107 TYR A N   1 
ATOM   2996 C CA  . TYR B 2 111 ? -12.81  -36.033 14.711  1   41.99  ? 107 TYR A CA  1 
ATOM   2997 C C   . TYR B 2 111 ? -12.822 -35.497 13.283  1   39.45  ? 107 TYR A C   1 
ATOM   2998 O O   . TYR B 2 111 ? -13.127 -34.325 13.087  1   37.91  ? 107 TYR A O   1 
ATOM   2999 C CB  . TYR B 2 111 ? -11.353 -36.118 15.21   1   41.37  ? 107 TYR A CB  1 
ATOM   3000 C CG  . TYR B 2 111 ? -11.147 -36.055 16.72   1   43.86  ? 107 TYR A CG  1 
ATOM   3001 C CD1 . TYR B 2 111 ? -12.217 -35.828 17.596  1   42.75  ? 107 TYR A CD1 1 
ATOM   3002 C CD2 . TYR B 2 111 ? -9.869  -36.207 17.277  1   43.58  ? 107 TYR A CD2 1 
ATOM   3003 C CE1 . TYR B 2 111 ? -12.004 -35.773 18.968  1   44.91  ? 107 TYR A CE1 1 
ATOM   3004 C CE2 . TYR B 2 111 ? -9.655  -36.148 18.647  1   42.08  ? 107 TYR A CE2 1 
ATOM   3005 C CZ  . TYR B 2 111 ? -10.721 -35.906 19.487  1   43.42  ? 107 TYR A CZ  1 
ATOM   3006 O OH  . TYR B 2 111 ? -10.556 -35.803 20.825  1   44.25  ? 107 TYR A OH  1 
ATOM   3007 N N   . LEU B 2 112 ? -12.428 -36.348 12.313  1   37.68  ? 108 LEU A N   1 
ATOM   3008 C CA  . LEU B 2 112 ? -12.394 -35.91  10.924  1   35.49  ? 108 LEU A CA  1 
ATOM   3009 C C   . LEU B 2 112 ? -13.811 -35.496 10.51   1   36.27  ? 108 LEU A C   1 
ATOM   3010 O O   . LEU B 2 112 ? -14.003 -34.466 9.866   1   37.48  ? 108 LEU A O   1 
ATOM   3011 C CB  . LEU B 2 112 ? -11.801 -36.988 10.017  1   32.75  ? 108 LEU A CB  1 
ATOM   3012 C CG  . LEU B 2 112 ? -11.665 -36.592 8.544   1   32.21  ? 108 LEU A CG  1 
ATOM   3013 C CD1 . LEU B 2 112 ? -10.829 -35.322 8.381   1   31.07  ? 108 LEU A CD1 1 
ATOM   3014 C CD2 . LEU B 2 112 ? -11.079 -37.705 7.676   1   31.38  ? 108 LEU A CD2 1 
ATOM   3015 N N   . PHE B 2 113 ? -14.8   -36.312 10.907  1   38.08  ? 109 PHE A N   1 
ATOM   3016 C CA  . PHE B 2 113 ? -16.192 -36.078 10.556  1   38.69  ? 109 PHE A CA  1 
ATOM   3017 C C   . PHE B 2 113 ? -16.639 -34.724 11.106  1   38.02  ? 109 PHE A C   1 
ATOM   3018 O O   . PHE B 2 113 ? -17.194 -33.903 10.381  1   38.8   ? 109 PHE A O   1 
ATOM   3019 C CB  . PHE B 2 113 ? -17.067 -37.201 11.092  1   39.69  ? 109 PHE A CB  1 
ATOM   3020 C CG  . PHE B 2 113 ? -18.457 -37.186 10.473  1   43.35  ? 109 PHE A CG  1 
ATOM   3021 C CD1 . PHE B 2 113 ? -18.637 -37.229 9.095   1   42.14  ? 109 PHE A CD1 1 
ATOM   3022 C CD2 . PHE B 2 113 ? -19.584 -37.118 11.281  1   45.39  ? 109 PHE A CD2 1 
ATOM   3023 C CE1 . PHE B 2 113 ? -19.912 -37.235 8.573   1   41.93  ? 109 PHE A CE1 1 
ATOM   3024 C CE2 . PHE B 2 113 ? -20.853 -37.128 10.754  1   43.87  ? 109 PHE A CE2 1 
ATOM   3025 C CZ  . PHE B 2 113 ? -21.009 -37.178 9.404   1   45.44  ? 109 PHE A CZ  1 
ATOM   3026 N N   . GLN B 2 114 ? -16.303 -34.445 12.368  1   37.97  ? 110 GLN A N   1 
ATOM   3027 C CA  . GLN B 2 114 ? -16.632 -33.152 12.945  1   37.02  ? 110 GLN A CA  1 
ATOM   3028 C C   . GLN B 2 114 ? -15.9   -32.007 12.249  1   37.08  ? 110 GLN A C   1 
ATOM   3029 O O   . GLN B 2 114 ? -16.511 -30.95  12.019  1   36.84  ? 110 GLN A O   1 
ATOM   3030 C CB  . GLN B 2 114 ? -16.284 -33.162 14.42   1   37.25  ? 110 GLN A CB  1 
ATOM   3031 C CG  . GLN B 2 114 ? -17.177 -34.075 15.24   1   38.9   ? 110 GLN A CG  1 
ATOM   3032 C CD  . GLN B 2 114 ? -16.826 -33.934 16.704  1   42.9   ? 110 GLN A CD  1 
ATOM   3033 O OE1 . GLN B 2 114 ? -16.999 -32.862 17.313  1   46.18  ? 110 GLN A OE1 1 
ATOM   3034 N NE2 . GLN B 2 114 ? -16.292 -35.01  17.274  1   41.7   ? 110 GLN A NE2 1 
ATOM   3035 N N   . LEU B 2 115 ? -14.609 -32.207 11.908  1   35.99  ? 111 LEU A N   1 
ATOM   3036 C CA  . LEU B 2 115 ? -13.826 -31.129 11.309  1   34.97  ? 111 LEU A CA  1 
ATOM   3037 C C   . LEU B 2 115 ? -14.462 -30.747 9.974   1   33.54  ? 111 LEU A C   1 
ATOM   3038 O O   . LEU B 2 115 ? -14.585 -29.573 9.651   1   31.56  ? 111 LEU A O   1 
ATOM   3039 C CB  . LEU B 2 115 ? -12.358 -31.527 11.11   1   35.02  ? 111 LEU A CB  1 
ATOM   3040 C CG  . LEU B 2 115 ? -11.529 -31.65  12.395  1   38.44  ? 111 LEU A CG  1 
ATOM   3041 C CD1 . LEU B 2 115 ? -10.227 -32.387 12.119  1   36.91  ? 111 LEU A CD1 1 
ATOM   3042 C CD2 . LEU B 2 115 ? -11.219 -30.268 13.011  1   38.46  ? 111 LEU A CD2 1 
ATOM   3043 N N   . LEU B 2 116 ? -14.871 -31.758 9.205   1   33.91  ? 112 LEU A N   1 
ATOM   3044 C CA  . LEU B 2 116 ? -15.553 -31.542 7.93    1   35.48  ? 112 LEU A CA  1 
ATOM   3045 C C   . LEU B 2 116 ? -16.874 -30.778 8.1     1   36.75  ? 112 LEU A C   1 
ATOM   3046 O O   . LEU B 2 116 ? -17.158 -29.868 7.308   1   38.09  ? 112 LEU A O   1 
ATOM   3047 C CB  . LEU B 2 116 ? -15.773 -32.871 7.203   1   35.56  ? 112 LEU A CB  1 
ATOM   3048 C CG  . LEU B 2 116 ? -14.48  -33.485 6.639   1   34.9   ? 112 LEU A CG  1 
ATOM   3049 C CD1 . LEU B 2 116 ? -14.619 -34.946 6.339   1   35.32  ? 112 LEU A CD1 1 
ATOM   3050 C CD2 . LEU B 2 116 ? -14.051 -32.754 5.396   1   34.91  ? 112 LEU A CD2 1 
ATOM   3051 N N   . GLN B 2 117 ? -17.667 -31.081 9.14    1   35.34  ? 113 GLN A N   1 
ATOM   3052 C CA  . GLN B 2 117 ? -18.892 -30.305 9.348   1   35.53  ? 113 GLN A CA  1 
ATOM   3053 C C   . GLN B 2 117 ? -18.555 -28.837 9.614   1   36.62  ? 113 GLN A C   1 
ATOM   3054 O O   . GLN B 2 117 ? -19.164 -27.956 9.037   1   35.22  ? 113 GLN A O   1 
ATOM   3055 C CB  . GLN B 2 117 ? -19.681 -30.797 10.548  1   34.65  ? 113 GLN A CB  1 
ATOM   3056 C CG  . GLN B 2 117 ? -20.188 -32.211 10.339  1   36.48  ? 113 GLN A CG  1 
ATOM   3057 C CD  . GLN B 2 117 ? -20.901 -32.735 11.559  1   38.34  ? 113 GLN A CD  1 
ATOM   3058 O OE1 . GLN B 2 117 ? -21.804 -32.097 12.118  1   38.89  ? 113 GLN A OE1 1 
ATOM   3059 N NE2 . GLN B 2 117 ? -20.465 -33.909 11.978  1   39.25  ? 113 GLN A NE2 1 
ATOM   3060 N N   . GLY B 2 118 ? -17.51  -28.583 10.434  1   39.7   ? 114 GLY A N   1 
ATOM   3061 C CA  . GLY B 2 118 ? -17.104 -27.229 10.797  1   35.74  ? 114 GLY A CA  1 
ATOM   3062 C C   . GLY B 2 118 ? -16.602 -26.445 9.595   1   33.64  ? 114 GLY A C   1 
ATOM   3063 O O   . GLY B 2 118 ? -16.931 -25.275 9.4     1   34.99  ? 114 GLY A O   1 
ATOM   3064 N N   . LEU B 2 119 ? -15.834 -27.12  8.752   1   34.38  ? 115 LEU A N   1 
ATOM   3065 C CA  . LEU B 2 119 ? -15.257 -26.484 7.576   1   34.45  ? 115 LEU A CA  1 
ATOM   3066 C C   . LEU B 2 119 ? -16.316 -26.201 6.521   1   37.23  ? 115 LEU A C   1 
ATOM   3067 O O   . LEU B 2 119 ? -16.321 -25.124 5.915   1   40.22  ? 115 LEU A O   1 
ATOM   3068 C CB  . LEU B 2 119 ? -14.191 -27.401 7.011   1   34.4   ? 115 LEU A CB  1 
ATOM   3069 C CG  . LEU B 2 119 ? -13.443 -26.788 5.833   1   36.69  ? 115 LEU A CG  1 
ATOM   3070 C CD1 . LEU B 2 119 ? -12.859 -25.404 6.207   1   33.89  ? 115 LEU A CD1 1 
ATOM   3071 C CD2 . LEU B 2 119 ? -12.377 -27.782 5.365   1   36.61  ? 115 LEU A CD2 1 
ATOM   3072 N N   . ALA B 2 120 ? -17.228 -27.165 6.326   1   36.44  ? 116 ALA A N   1 
ATOM   3073 C CA  . ALA B 2 120 ? -18.343 -26.945 5.422   1   36.38  ? 116 ALA A CA  1 
ATOM   3074 C C   . ALA B 2 120 ? -19.18  -25.764 5.908   1   36.68  ? 116 ALA A C   1 
ATOM   3075 O O   . ALA B 2 120 ? -19.681 -24.985 5.094   1   38.46  ? 116 ALA A O   1 
ATOM   3076 C CB  . ALA B 2 120 ? -19.18  -28.21  5.312   1   34.77  ? 116 ALA A CB  1 
ATOM   3077 N N   . PHE B 2 121 ? -19.353 -25.635 7.229   1   35.04  ? 117 PHE A N   1 
ATOM   3078 C CA  . PHE B 2 121 ? -20.133 -24.513 7.717   1   35.36  ? 117 PHE A CA  1 
ATOM   3079 C C   . PHE B 2 121 ? -19.406 -23.225 7.322   1   37.6   ? 117 PHE A C   1 
ATOM   3080 O O   . PHE B 2 121 ? -20.069 -22.314 6.833   1   38.84  ? 117 PHE A O   1 
ATOM   3081 C CB  . PHE B 2 121 ? -20.385 -24.594 9.223   1   34.3   ? 117 PHE A CB  1 
ATOM   3082 C CG  . PHE B 2 121 ? -21.368 -23.545 9.725   1   34.62  ? 117 PHE A CG  1 
ATOM   3083 C CD1 . PHE B 2 121 ? -20.942 -22.259 10.05   1   33.03  ? 117 PHE A CD1 1 
ATOM   3084 C CD2 . PHE B 2 121 ? -22.738 -23.848 9.811   1   35.95  ? 117 PHE A CD2 1 
ATOM   3085 C CE1 . PHE B 2 121 ? -21.862 -21.312 10.472  1   35.73  ? 117 PHE A CE1 1 
ATOM   3086 C CE2 . PHE B 2 121 ? -23.67  -22.908 10.27   1   35.94  ? 117 PHE A CE2 1 
ATOM   3087 C CZ  . PHE B 2 121 ? -23.239 -21.629 10.587  1   36.23  ? 117 PHE A CZ  1 
ATOM   3088 N N   . CYS B 2 122 ? -18.059 -23.188 7.457   1   33.39  ? 118 CYS A N   1 
ATOM   3089 C CA  . CYS B 2 122 ? -17.304 -22.004 7.074   1   34.07  ? 118 CYS A CA  1 
ATOM   3090 C C   . CYS B 2 122 ? -17.526 -21.643 5.608   1   33.35  ? 118 CYS A C   1 
ATOM   3091 O O   . CYS B 2 122 ? -17.796 -20.499 5.279   1   34.85  ? 118 CYS A O   1 
ATOM   3092 C CB  . CYS B 2 122 ? -15.797 -22.203 7.287   1   34.09  ? 118 CYS A CB  1 
ATOM   3093 S SG  . CYS B 2 122 ? -15.38  -22.276 9.044   1   36.06  ? 118 CYS A SG  1 
ATOM   3094 N N   . HIS B 2 123 ? -17.309 -22.61  4.724   1   33.87  ? 119 HIS A N   1 
ATOM   3095 C CA  . HIS B 2 123 ? -17.385 -22.38  3.291   1   34.26  ? 119 HIS A CA  1 
ATOM   3096 C C   . HIS B 2 123 ? -18.809 -21.995 2.904   1   38.45  ? 119 HIS A C   1 
ATOM   3097 O O   . HIS B 2 123 ? -18.985 -21.219 1.967   1   45.1   ? 119 HIS A O   1 
ATOM   3098 C CB  . HIS B 2 123 ? -16.936 -23.64  2.545   1   34.64  ? 119 HIS A CB  1 
ATOM   3099 C CG  . HIS B 2 123 ? -15.498 -23.939 2.779   1   36.83  ? 119 HIS A CG  1 
ATOM   3100 N ND1 . HIS B 2 123 ? -14.839 -25.056 2.311   1   38.83  ? 119 HIS A ND1 1 
ATOM   3101 C CD2 . HIS B 2 123 ? -14.572 -23.181 3.41    1   36.12  ? 119 HIS A CD2 1 
ATOM   3102 C CE1 . HIS B 2 123 ? -13.556 -24.966 2.696   1   42.3   ? 119 HIS A CE1 1 
ATOM   3103 N NE2 . HIS B 2 123 ? -13.379 -23.837 3.389   1   37.91  ? 119 HIS A NE2 1 
ATOM   3104 N N   . SER B 2 124 ? -19.817 -22.54  3.6     1   35.73  ? 120 SER A N   1 
ATOM   3105 C CA  . SER B 2 124 ? -21.212 -22.165 3.353   1   39.47  ? 120 SER A CA  1 
ATOM   3106 C C   . SER B 2 124 ? -21.473 -20.712 3.743   1   39.49  ? 120 SER A C   1 
ATOM   3107 O O   . SER B 2 124 ? -22.445 -20.092 3.282   1   38.02  ? 120 SER A O   1 
ATOM   3108 C CB  . SER B 2 124 ? -22.199 -23.068 4.096   1   38.49  ? 120 SER A CB  1 
ATOM   3109 O OG  . SER B 2 124 ? -22.151 -24.385 3.563   1   40.15  ? 120 SER A OG  1 
ATOM   3110 N N   . HIS B 2 125 ? -20.61  -20.203 4.632   1   37.52  ? 121 HIS A N   1 
ATOM   3111 C CA  . HIS B 2 125 ? -20.708 -18.835 5.1     1   38.87  ? 121 HIS A CA  1 
ATOM   3112 C C   . HIS B 2 125 ? -19.6   -17.955 4.494   1   39.68  ? 121 HIS A C   1 
ATOM   3113 O O   . HIS B 2 125 ? -19.236 -16.952 5.098   1   40.18  ? 121 HIS A O   1 
ATOM   3114 C CB  . HIS B 2 125 ? -20.824 -18.859 6.618   1   37.74  ? 121 HIS A CB  1 
ATOM   3115 C CG  . HIS B 2 125 ? -22.101 -19.519 7.032   1   41.37  ? 121 HIS A CG  1 
ATOM   3116 N ND1 . HIS B 2 125 ? -22.252 -20.892 7.043   1   41.81  ? 121 HIS A ND1 1 
ATOM   3117 C CD2 . HIS B 2 125 ? -23.288 -19.015 7.422   1   41.58  ? 121 HIS A CD2 1 
ATOM   3118 C CE1 . HIS B 2 125 ? -23.491 -21.192 7.439   1   43.95  ? 121 HIS A CE1 1 
ATOM   3119 N NE2 . HIS B 2 125 ? -24.129 -20.065 7.672   1   43.95  ? 121 HIS A NE2 1 
ATOM   3120 N N   . ARG B 2 126 ? -19.123 -18.296 3.278   1   37.93  ? 122 ARG A N   1 
ATOM   3121 C CA  . ARG B 2 126 ? -18.068 -17.582 2.551   1   37.58  ? 122 ARG A CA  1 
ATOM   3122 C C   . ARG B 2 126 ? -16.844 -17.243 3.425   1   37.51  ? 122 ARG A C   1 
ATOM   3123 O O   . ARG B 2 126 ? -16.248 -16.171 3.253   1   38.23  ? 122 ARG A O   1 
ATOM   3124 C CB  . ARG B 2 126 ? -18.654 -16.359 1.833   1   38.49  ? 122 ARG A CB  1 
ATOM   3125 C CG  . ARG B 2 126 ? -19.497 -15.438 2.72    1   40.65  ? 122 ARG A CG  1 
ATOM   3126 C CD  . ARG B 2 126 ? -18.68  -14.23  3.153   1   41.22  ? 122 ARG A CD  1 
ATOM   3127 N NE  . ARG B 2 126 ? -19.481 -13.241 3.874   1   45.17  ? 122 ARG A NE  1 
ATOM   3128 C CZ  . ARG B 2 126 ? -19.826 -13.268 5.187   1   44.93  ? 122 ARG A CZ  1 
ATOM   3129 N NH1 . ARG B 2 126 ? -19.473 -14.292 5.961   1   41.02  ? 122 ARG A NH1 1 
ATOM   3130 N NH2 . ARG B 2 126 ? -20.522 -12.264 5.713   1   43.62  ? 122 ARG A NH2 1 
ATOM   3131 N N   . VAL B 2 127 ? -16.412 -18.174 4.296   1   35.02  ? 123 VAL A N   1 
ATOM   3132 C CA  . VAL B 2 127 ? -15.188 -18.008 5.071   1   34.03  ? 123 VAL A CA  1 
ATOM   3133 C C   . VAL B 2 127 ? -14.169 -19.096 4.718   1   35.86  ? 123 VAL A C   1 
ATOM   3134 O O   . VAL B 2 127 ? -14.466 -20.281 4.847   1   36.07  ? 123 VAL A O   1 
ATOM   3135 C CB  . VAL B 2 127 ? -15.486 -17.964 6.58    1   33.47  ? 123 VAL A CB  1 
ATOM   3136 C CG1 . VAL B 2 127 ? -14.208 -18.024 7.445   1   32.85  ? 123 VAL A CG1 1 
ATOM   3137 C CG2 . VAL B 2 127 ? -16.324 -16.732 6.921   1   32.49  ? 123 VAL A CG2 1 
ATOM   3138 N N   . LEU B 2 128 ? -12.964 -18.68  4.291   1   35.47  ? 124 LEU A N   1 
ATOM   3139 C CA  . LEU B 2 128 ? -11.766 -19.517 4.231   1   36.65  ? 124 LEU A CA  1 
ATOM   3140 C C   . LEU B 2 128 ? -11.044 -19.436 5.576   1   37.73  ? 124 LEU A C   1 
ATOM   3141 O O   . LEU B 2 128 ? -10.803 -18.33  6.073   1   44.2   ? 124 LEU A O   1 
ATOM   3142 C CB  . LEU B 2 128 ? -10.786 -19.044 3.143   1   34.9   ? 124 LEU A CB  1 
ATOM   3143 C CG  . LEU B 2 128 ? -11.25  -19.133 1.688   1   36.01  ? 124 LEU A CG  1 
ATOM   3144 C CD1 . LEU B 2 128 ? -10.166 -18.799 0.705   1   34.88  ? 124 LEU A CD1 1 
ATOM   3145 C CD2 . LEU B 2 128 ? -11.76  -20.533 1.403   1   35.91  ? 124 LEU A CD2 1 
ATOM   3146 N N   . HIS B 2 129 ? -10.623 -20.585 6.125   1   34.95  ? 125 HIS A N   1 
ATOM   3147 C CA  . HIS B 2 129 ? -9.904  -20.568 7.387   1   33.86  ? 125 HIS A CA  1 
ATOM   3148 C C   . HIS B 2 129 ? -8.428  -20.176 7.187   1   35.13  ? 125 HIS A C   1 
ATOM   3149 O O   . HIS B 2 129 ? -7.951  -19.236 7.815   1   35.11  ? 125 HIS A O   1 
ATOM   3150 C CB  . HIS B 2 129 ? -10.096 -21.898 8.114   1   31.8   ? 125 HIS A CB  1 
ATOM   3151 C CG  . HIS B 2 129 ? -9.403  -21.906 9.442   1   34.43  ? 125 HIS A CG  1 
ATOM   3152 N ND1 . HIS B 2 129 ? -8.03   -22.108 9.571   1   33.22  ? 125 HIS A ND1 1 
ATOM   3153 C CD2 . HIS B 2 129 ? -9.886  -21.718 10.683  1   34.4   ? 125 HIS A CD2 1 
ATOM   3154 C CE1 . HIS B 2 129 ? -7.709  -22.044 10.857  1   35.1   ? 125 HIS A CE1 1 
ATOM   3155 N NE2 . HIS B 2 129 ? -8.822  -21.8   11.569  1   37.89  ? 125 HIS A NE2 1 
ATOM   3156 N N   . ARG B 2 130 ? -7.706  -20.932 6.345   1   35.33  ? 126 ARG A N   1 
ATOM   3157 C CA  . ARG B 2 130 ? -6.385  -20.551 5.836   1   38.68  ? 126 ARG A CA  1 
ATOM   3158 C C   . ARG B 2 130 ? -5.276  -20.836 6.85    1   39.69  ? 126 ARG A C   1 
ATOM   3159 O O   . ARG B 2 130 ? -4.151  -20.351 6.7     1   49.05  ? 126 ARG A O   1 
ATOM   3160 C CB  . ARG B 2 130 ? -6.319  -19.087 5.368   1   36.94  ? 126 ARG A CB  1 
ATOM   3161 C CG  . ARG B 2 130 ? -7.248  -18.849 4.179   1   35.67  ? 126 ARG A CG  1 
ATOM   3162 C CD  . ARG B 2 130 ? -6.944  -17.594 3.381   1   35.38  ? 126 ARG A CD  1 
ATOM   3163 N NE  . ARG B 2 130 ? -6.958  -16.468 4.317   1   35.72  ? 126 ARG A NE  1 
ATOM   3164 C CZ  . ARG B 2 130 ? -6.534  -15.237 4       1   38.13  ? 126 ARG A CZ  1 
ATOM   3165 N NH1 . ARG B 2 130 ? -6.128  -14.972 2.776   1   38.36  ? 126 ARG A NH1 1 
ATOM   3166 N NH2 . ARG B 2 130 ? -6.564  -14.27  4.904   1   37.71  ? 126 ARG A NH2 1 
ATOM   3167 N N   . ASP B 2 131 ? -5.565  -21.635 7.874   1   37.18  ? 127 ASP A N   1 
ATOM   3168 C CA  . ASP B 2 131 ? -4.511  -22.04  8.782   1   34.72  ? 127 ASP A CA  1 
ATOM   3169 C C   . ASP B 2 131 ? -4.93   -23.28  9.547   1   34.29  ? 127 ASP A C   1 
ATOM   3170 O O   . ASP B 2 131 ? -4.747  -23.338 10.761  1   35.71  ? 127 ASP A O   1 
ATOM   3171 C CB  . ASP B 2 131 ? -4.059  -20.957 9.756   1   37.67  ? 127 ASP A CB  1 
ATOM   3172 C CG  . ASP B 2 131 ? -2.589  -21.122 10.151  1   41.59  ? 127 ASP A CG  1 
ATOM   3173 O OD1 . ASP B 2 131 ? -1.878  -21.879 9.448   1   43.71  ? 127 ASP A OD1 1 
ATOM   3174 O OD2 . ASP B 2 131 ? -2.171  -20.567 11.165  1   43     ? 127 ASP A OD2 1 
ATOM   3175 N N   . LEU B 2 132 ? -5.49   -24.26  8.842   1   33.23  ? 128 LEU A N   1 
ATOM   3176 C CA  . LEU B 2 132 ? -5.87   -25.492 9.506   1   36.05  ? 128 LEU A CA  1 
ATOM   3177 C C   . LEU B 2 132 ? -4.621  -26.34  9.772   1   39.09  ? 128 LEU A C   1 
ATOM   3178 O O   . LEU B 2 132 ? -3.905  -26.764 8.859   1   39.9   ? 128 LEU A O   1 
ATOM   3179 C CB  . LEU B 2 132 ? -6.876  -26.191 8.587   1   35.3   ? 128 LEU A CB  1 
ATOM   3180 C CG  . LEU B 2 132 ? -8.238  -25.476 8.466   1   34.81  ? 128 LEU A CG  1 
ATOM   3181 C CD1 . LEU B 2 132 ? -9.149  -26.19  7.483   1   31.04  ? 128 LEU A CD1 1 
ATOM   3182 C CD2 . LEU B 2 132 ? -8.887  -25.375 9.841   1   32     ? 128 LEU A CD2 1 
ATOM   3183 N N   . LYS B 2 133 ? -4.372  -26.572 11.048  1   36.16  ? 129 LYS A N   1 
ATOM   3184 C CA  . LYS B 2 133 ? -3.298  -27.426 11.498  1   39.09  ? 129 LYS A CA  1 
ATOM   3185 C C   . LYS B 2 133 ? -3.707  -27.872 12.897  1   42.66  ? 129 LYS A C   1 
ATOM   3186 O O   . LYS B 2 133 ? -4.613  -27.281 13.5    1   44.27  ? 129 LYS A O   1 
ATOM   3187 C CB  . LYS B 2 133 ? -2.016  -26.597 11.533  1   36.67  ? 129 LYS A CB  1 
ATOM   3188 C CG  . LYS B 2 133 ? -2.118  -25.291 12.299  1   37.84  ? 129 LYS A CG  1 
ATOM   3189 C CD  . LYS B 2 133 ? -0.714  -24.736 12.512  1   41.94  ? 129 LYS A CD  1 
ATOM   3190 C CE  . LYS B 2 133 ? -0.708  -23.276 12.868  1   45.76  ? 129 LYS A CE  1 
ATOM   3191 N NZ  . LYS B 2 133 ? 0.676   -22.814 13.041  1   46.55  ? 129 LYS A NZ  1 
ATOM   3192 N N   . PRO B 2 134 ? -3.096  -28.936 13.449  1   42.74  ? 130 PRO A N   1 
ATOM   3193 C CA  . PRO B 2 134 ? -3.571  -29.52  14.704  1   43.8   ? 130 PRO A CA  1 
ATOM   3194 C C   . PRO B 2 134 ? -3.58   -28.612 15.928  1   47.54  ? 130 PRO A C   1 
ATOM   3195 O O   . PRO B 2 134 ? -4.426  -28.799 16.809  1   49.59  ? 130 PRO A O   1 
ATOM   3196 C CB  . PRO B 2 134 ? -2.682  -30.742 14.875  1   41.42  ? 130 PRO A CB  1 
ATOM   3197 C CG  . PRO B 2 134 ? -2.301  -31.085 13.468  1   40.52  ? 130 PRO A CG  1 
ATOM   3198 C CD  . PRO B 2 134 ? -2.034  -29.73  12.825  1   41.25  ? 130 PRO A CD  1 
ATOM   3199 N N   . GLN B 2 135 ? -2.647  -27.65  15.98   1   45.14  ? 131 GLN A N   1 
ATOM   3200 C CA  . GLN B 2 135 ? -2.551  -26.759 17.128  1   47.6   ? 131 GLN A CA  1 
ATOM   3201 C C   . GLN B 2 135 ? -3.711  -25.759 17.123  1   45.55  ? 131 GLN A C   1 
ATOM   3202 O O   . GLN B 2 135 ? -3.927  -25.042 18.109  1   43.37  ? 131 GLN A O   1 
ATOM   3203 C CB  . GLN B 2 135 ? -1.166  -26.122 17.274  1   50.07  ? 131 GLN A CB  1 
ATOM   3204 C CG  . GLN B 2 135 ? -0.068  -27.13  17.573  1   59.99  ? 131 GLN A CG  1 
ATOM   3205 C CD  . GLN B 2 135 ? 0.539   -27.814 16.35   1   57.59  ? 131 GLN A CD  1 
ATOM   3206 O OE1 . GLN B 2 135 ? 0.148   -27.55  15.209  1   63.77  ? 131 GLN A OE1 1 
ATOM   3207 N NE2 . GLN B 2 135 ? 1.476   -28.734 16.542  1   45.33  ? 131 GLN A NE2 1 
ATOM   3208 N N   . ASN B 2 136 ? -4.453  -25.731 16.005  1   40.64  ? 132 ASN A N   1 
ATOM   3209 C CA  . ASN B 2 136 ? -5.558  -24.805 15.841  1   42.85  ? 132 ASN A CA  1 
ATOM   3210 C C   . ASN B 2 136 ? -6.903  -25.548 15.906  1   42.6   ? 132 ASN A C   1 
ATOM   3211 O O   . ASN B 2 136 ? -7.934  -24.987 15.559  1   41.66  ? 132 ASN A O   1 
ATOM   3212 C CB  . ASN B 2 136 ? -5.406  -24.026 14.538  1   39.89  ? 132 ASN A CB  1 
ATOM   3213 C CG  . ASN B 2 136 ? -4.436  -22.886 14.664  1   40.32  ? 132 ASN A CG  1 
ATOM   3214 O OD1 . ASN B 2 136 ? -4.019  -22.556 15.77   1   42.32  ? 132 ASN A OD1 1 
ATOM   3215 N ND2 . ASN B 2 136 ? -4.056  -22.276 13.556  1   40.31  ? 132 ASN A ND2 1 
ATOM   3216 N N   . LEU B 2 137 ? -6.872  -26.831 16.288  1   40.64  ? 133 LEU A N   1 
ATOM   3217 C CA  . LEU B 2 137 ? -8.066  -27.64  16.45   1   37.83  ? 133 LEU A CA  1 
ATOM   3218 C C   . LEU B 2 137 ? -8.18   -28.019 17.929  1   40.2   ? 133 LEU A C   1 
ATOM   3219 O O   . LEU B 2 137 ? -7.331  -28.736 18.482  1   42.92  ? 133 LEU A O   1 
ATOM   3220 C CB  . LEU B 2 137 ? -7.937  -28.868 15.548  1   36.51  ? 133 LEU A CB  1 
ATOM   3221 C CG  . LEU B 2 137 ? -7.605  -28.579 14.085  1   36.08  ? 133 LEU A CG  1 
ATOM   3222 C CD1 . LEU B 2 137 ? -7.572  -29.86  13.244  1   35.46  ? 133 LEU A CD1 1 
ATOM   3223 C CD2 . LEU B 2 137 ? -8.614  -27.598 13.522  1   34.69  ? 133 LEU A CD2 1 
ATOM   3224 N N   . LEU B 2 138 ? -9.244  -27.537 18.573  1   39.38  ? 134 LEU A N   1 
ATOM   3225 C CA  . LEU B 2 138 ? -9.426  -27.724 20      1   40.99  ? 134 LEU A CA  1 
ATOM   3226 C C   . LEU B 2 138 ? -10.382 -28.88  20.269  1   40.69  ? 134 LEU A C   1 
ATOM   3227 O O   . LEU B 2 138 ? -11.364 -29.025 19.56   1   44.08  ? 134 LEU A O   1 
ATOM   3228 C CB  . LEU B 2 138 ? -9.944  -26.394 20.537  1   39.69  ? 134 LEU A CB  1 
ATOM   3229 C CG  . LEU B 2 138 ? -8.999  -25.211 20.28   1   43.26  ? 134 LEU A CG  1 
ATOM   3230 C CD1 . LEU B 2 138 ? -9.645  -23.933 20.714  1   41.74  ? 134 LEU A CD1 1 
ATOM   3231 C CD2 . LEU B 2 138 ? -7.574  -25.323 20.914  1   43.1   ? 134 LEU A CD2 1 
ATOM   3232 N N   . ILE B 2 139 ? -10.062 -29.693 21.276  1   38.72  ? 135 ILE A N   1 
ATOM   3233 C CA  . ILE B 2 139 ? -10.863 -30.813 21.722  1   38.29  ? 135 ILE A CA  1 
ATOM   3234 C C   . ILE B 2 139 ? -11.316 -30.562 23.153  1   40.51  ? 135 ILE A C   1 
ATOM   3235 O O   . ILE B 2 139 ? -10.623 -29.905 23.932  1   40.71  ? 135 ILE A O   1 
ATOM   3236 C CB  . ILE B 2 139 ? -10.061 -32.12  21.659  1   39.17  ? 135 ILE A CB  1 
ATOM   3237 C CG1 . ILE B 2 139 ? -8.82   -32.107 22.544  1   39.49  ? 135 ILE A CG1 1 
ATOM   3238 C CG2 . ILE B 2 139 ? -9.683  -32.444 20.221  1   38.9   ? 135 ILE A CG2 1 
ATOM   3239 C CD1 . ILE B 2 139 ? -8.203  -33.479 22.713  1   41.44  ? 135 ILE A CD1 1 
ATOM   3240 N N   . ASN B 2 140 ? -12.463 -31.148 23.514  1   42.02  ? 136 ASN A N   1 
ATOM   3241 C CA  . ASN B 2 140 ? -12.961 -31.059 24.876  1   43.4   ? 136 ASN A CA  1 
ATOM   3242 C C   . ASN B 2 140 ? -13.002 -32.442 25.524  1   44.84  ? 136 ASN A C   1 
ATOM   3243 O O   . ASN B 2 140 ? -12.633 -33.433 24.896  1   44.43  ? 136 ASN A O   1 
ATOM   3244 C CB  . ASN B 2 140 ? -14.31  -30.35  24.914  1   44.49  ? 136 ASN A CB  1 
ATOM   3245 C CG  . ASN B 2 140 ? -15.449 -31.131 24.296  1   45.91  ? 136 ASN A CG  1 
ATOM   3246 O OD1 . ASN B 2 140 ? -15.398 -32.352 24.054  1   46.49  ? 136 ASN A OD1 1 
ATOM   3247 N ND2 . ASN B 2 140 ? -16.524 -30.411 24.053  1   46.16  ? 136 ASN A ND2 1 
ATOM   3248 N N   . THR B 2 141 ? -13.47  -32.502 26.785  1   48.58  ? 137 THR A N   1 
ATOM   3249 C CA  . THR B 2 141 ? -13.58  -33.779 27.472  1   52.3   ? 137 THR A CA  1 
ATOM   3250 C C   . THR B 2 141 ? -14.724 -34.621 26.888  1   55.51  ? 137 THR A C   1 
ATOM   3251 O O   . THR B 2 141 ? -14.804 -35.808 27.195  1   59.08  ? 137 THR A O   1 
ATOM   3252 C CB  . THR B 2 141 ? -13.782 -33.576 28.97   1   53.64  ? 137 THR A CB  1 
ATOM   3253 O OG1 . THR B 2 141 ? -14.726 -32.519 29.024  1   56.25  ? 137 THR A OG1 1 
ATOM   3254 C CG2 . THR B 2 141 ? -12.534 -33.091 29.672  1   54.63  ? 137 THR A CG2 1 
ATOM   3255 N N   . GLU B 2 142 ? -15.592 -34.035 26.054  1   53.82  ? 138 GLU A N   1 
ATOM   3256 C CA  . GLU B 2 142 ? -16.818 -34.715 25.654  1   60.16  ? 138 GLU A CA  1 
ATOM   3257 C C   . GLU B 2 142 ? -16.632 -35.487 24.345  1   58.18  ? 138 GLU A C   1 
ATOM   3258 O O   . GLU B 2 142 ? -17.48  -36.303 24.004  1   57.45  ? 138 GLU A O   1 
ATOM   3259 C CB  . GLU B 2 142 ? -17.982 -33.74  25.431  1   63.65  ? 138 GLU A CB  1 
ATOM   3260 C CG  . GLU B 2 142 ? -18.512 -33.093 26.706  1   66.36  ? 138 GLU A CG  1 
ATOM   3261 C CD  . GLU B 2 142 ? -19.088 -34.096 27.674  1   73.03  ? 138 GLU A CD  1 
ATOM   3262 O OE1 . GLU B 2 142 ? -19.977 -34.901 27.292  1   73.74  ? 138 GLU A OE1 1 
ATOM   3263 O OE2 . GLU B 2 142 ? -18.635 -34.038 28.838  1   80.43  ? 138 GLU A OE2 1 
ATOM   3264 N N   . GLY B 2 143 ? -15.578 -35.187 23.575  1   50.72  ? 139 GLY A N   1 
ATOM   3265 C CA  . GLY B 2 143 ? -15.357 -35.886 22.318  1   44.47  ? 139 GLY A CA  1 
ATOM   3266 C C   . GLY B 2 143 ? -15.545 -34.956 21.124  1   41.1   ? 139 GLY A C   1 
ATOM   3267 O O   . GLY B 2 143 ? -15.413 -35.408 19.98   1   39.62  ? 139 GLY A O   1 
ATOM   3268 N N   . ALA B 2 144 ? -15.817 -33.669 21.403  1   39.45  ? 140 ALA A N   1 
ATOM   3269 C CA  . ALA B 2 144 ? -15.883 -32.665 20.346  1   39.66  ? 140 ALA A CA  1 
ATOM   3270 C C   . ALA B 2 144 ? -14.489 -32.177 19.957  1   41.68  ? 140 ALA A C   1 
ATOM   3271 O O   . ALA B 2 144 ? -13.546 -32.197 20.767  1   45.98  ? 140 ALA A O   1 
ATOM   3272 C CB  . ALA B 2 144 ? -16.69  -31.504 20.824  1   38.98  ? 140 ALA A CB  1 
ATOM   3273 N N   . ILE B 2 145 ? -14.37  -31.765 18.69   1   39.99  ? 141 ILE A N   1 
ATOM   3274 C CA  . ILE B 2 145 ? -13.206 -31.052 18.193  1   39.03  ? 141 ILE A CA  1 
ATOM   3275 C C   . ILE B 2 145 ? -13.73  -29.866 17.39   1   38.57  ? 141 ILE A C   1 
ATOM   3276 O O   . ILE B 2 145 ? -14.763 -30.015 16.736  1   37.54  ? 141 ILE A O   1 
ATOM   3277 C CB  . ILE B 2 145 ? -12.313 -31.968 17.345  1   39.24  ? 141 ILE A CB  1 
ATOM   3278 C CG1 . ILE B 2 145 ? -10.988 -31.287 16.937  1   37.97  ? 141 ILE A CG1 1 
ATOM   3279 C CG2 . ILE B 2 145 ? -13.082 -32.449 16.121  1   40.59  ? 141 ILE A CG2 1 
ATOM   3280 C CD1 . ILE B 2 145 ? -9.935  -32.255 16.416  1   37.29  ? 141 ILE A CD1 1 
ATOM   3281 N N   . LYS B 2 146 ? -13.046 -28.701 17.469  1   36.14  ? 142 LYS A N   1 
ATOM   3282 C CA  . LYS B 2 146 ? -13.591 -27.486 16.885  1   36.63  ? 142 LYS A CA  1 
ATOM   3283 C C   . LYS B 2 146 ? -12.493 -26.704 16.179  1   39.28  ? 142 LYS A C   1 
ATOM   3284 O O   . LYS B 2 146 ? -11.402 -26.613 16.735  1   43.38  ? 142 LYS A O   1 
ATOM   3285 C CB  . LYS B 2 146 ? -14.213 -26.633 17.992  1   35.65  ? 142 LYS A CB  1 
ATOM   3286 C CG  . LYS B 2 146 ? -15.147 -27.425 18.9    1   36.06  ? 142 LYS A CG  1 
ATOM   3287 C CD  . LYS B 2 146 ? -16.071 -26.562 19.761  1   37.55  ? 142 LYS A CD  1 
ATOM   3288 C CE  . LYS B 2 146 ? -16.976 -27.368 20.662  1   38.5   ? 142 LYS A CE  1 
ATOM   3289 N NZ  . LYS B 2 146 ? -18.164 -26.558 20.998  1   40.14  ? 142 LYS A NZ  1 
ATOM   3290 N N   . LEU B 2 147 ? -12.809 -26.091 15.019  1   37.61  ? 143 LEU A N   1 
ATOM   3291 C CA  . LEU B 2 147 ? -11.868 -25.209 14.339  1   39.38  ? 143 LEU A CA  1 
ATOM   3292 C C   . LEU B 2 147 ? -11.586 -24     15.23   1   40.83  ? 143 LEU A C   1 
ATOM   3293 O O   . LEU B 2 147 ? -12.506 -23.429 15.79   1   41.67  ? 143 LEU A O   1 
ATOM   3294 C CB  . LEU B 2 147 ? -12.369 -24.735 12.973  1   37.59  ? 143 LEU A CB  1 
ATOM   3295 C CG  . LEU B 2 147 ? -12.944 -25.778 12.009  1   37.59  ? 143 LEU A CG  1 
ATOM   3296 C CD1 . LEU B 2 147 ? -12.807 -25.229 10.608  1   37.21  ? 143 LEU A CD1 1 
ATOM   3297 C CD2 . LEU B 2 147 ? -12.319 -27.135 12.118  1   35.46  ? 143 LEU A CD2 1 
ATOM   3298 N N   . ALA B 2 148 ? -10.313 -23.616 15.379  1   39.26  ? 144 ALA A N   1 
ATOM   3299 C CA  . ALA B 2 148 ? -10.01  -22.404 16.128  1   40.58  ? 144 ALA A CA  1 
ATOM   3300 C C   . ALA B 2 148 ? -9.029  -21.529 15.353  1   41.43  ? 144 ALA A C   1 
ATOM   3301 O O   . ALA B 2 148 ? -8.546  -21.907 14.262  1   40.27  ? 144 ALA A O   1 
ATOM   3302 C CB  . ALA B 2 148 ? -9.489  -22.728 17.53   1   40.25  ? 144 ALA A CB  1 
ATOM   3303 N N   . ASP B 2 149 ? -8.78   -20.353 15.95   1   43     ? 145 ASP A N   1 
ATOM   3304 C CA  . ASP B 2 149 ? -7.859  -19.345 15.455  1   46.05  ? 145 ASP A CA  1 
ATOM   3305 C C   . ASP B 2 149 ? -8.22   -18.91  14.04   1   43.69  ? 145 ASP A C   1 
ATOM   3306 O O   . ASP B 2 149 ? -7.652  -19.423 13.074  1   45.36  ? 145 ASP A O   1 
ATOM   3307 C CB  . ASP B 2 149 ? -6.396  -19.77  15.496  1   48.89  ? 145 ASP A CB  1 
ATOM   3308 C CG  . ASP B 2 149 ? -5.417  -18.601 15.466  1   53.68  ? 145 ASP A CG  1 
ATOM   3309 O OD1 . ASP B 2 149 ? -5.84   -17.426 15.266  1   53.62  ? 145 ASP A OD1 1 
ATOM   3310 O OD2 . ASP B 2 149 ? -4.231  -18.859 15.707  1   62.73  ? 145 ASP A OD2 1 
ATOM   3311 N N   . PHE B 2 150 ? -9.114  -17.917 13.97   1   40.76  ? 146 PHE A N   1 
ATOM   3312 C CA  . PHE B 2 150 ? -9.572  -17.339 12.72   1   40.76  ? 146 PHE A CA  1 
ATOM   3313 C C   . PHE B 2 150 ? -8.842  -16.03  12.407  1   42.82  ? 146 PHE A C   1 
ATOM   3314 O O   . PHE B 2 150 ? -9.285  -15.279 11.554  1   40.17  ? 146 PHE A O   1 
ATOM   3315 C CB  . PHE B 2 150 ? -11.086 -17.148 12.812  1   38.12  ? 146 PHE A CB  1 
ATOM   3316 C CG  . PHE B 2 150 ? -11.842 -18.437 12.547  1   33.92  ? 146 PHE A CG  1 
ATOM   3317 C CD1 . PHE B 2 150 ? -11.884 -19.442 13.51   1   32.84  ? 146 PHE A CD1 1 
ATOM   3318 C CD2 . PHE B 2 150 ? -12.552 -18.615 11.362  1   32.12  ? 146 PHE A CD2 1 
ATOM   3319 C CE1 . PHE B 2 150 ? -12.591 -20.621 13.281  1   30.85  ? 146 PHE A CE1 1 
ATOM   3320 C CE2 . PHE B 2 150 ? -13.232 -19.797 11.123  1   30.47  ? 146 PHE A CE2 1 
ATOM   3321 C CZ  . PHE B 2 150 ? -13.261 -20.794 12.084  1   29.86  ? 146 PHE A CZ  1 
ATOM   3322 N N   . GLY B 2 151 ? -7.69   -15.779 13.061  1   44.71  ? 147 GLY A N   1 
ATOM   3323 C CA  . GLY B 2 151 ? -6.846  -14.623 12.763  1   42.52  ? 147 GLY A CA  1 
ATOM   3324 C C   . GLY B 2 151 ? -6.401  -14.55  11.303  1   40.8   ? 147 GLY A C   1 
ATOM   3325 O O   . GLY B 2 151 ? -6.32   -13.463 10.744  1   43.77  ? 147 GLY A O   1 
ATOM   3326 N N   . LEU B 2 152 ? -6.217  -15.695 10.658  1   39.03  ? 148 LEU A N   1 
ATOM   3327 C CA  . LEU B 2 152 ? -5.83   -15.677 9.252   1   44.2   ? 148 LEU A CA  1 
ATOM   3328 C C   . LEU B 2 152 ? -6.98   -15.923 8.269   1   42.12  ? 148 LEU A C   1 
ATOM   3329 O O   . LEU B 2 152 ? -6.714  -16.119 7.091   1   42.59  ? 148 LEU A O   1 
ATOM   3330 C CB  . LEU B 2 152 ? -4.665  -16.642 9.012   1   46.42  ? 148 LEU A CB  1 
ATOM   3331 C CG  . LEU B 2 152 ? -3.507  -16.395 9.983   1   55.26  ? 148 LEU A CG  1 
ATOM   3332 C CD1 . LEU B 2 152 ? -3.505  -17.415 11.18   1   58.67  ? 148 LEU A CD1 1 
ATOM   3333 C CD2 . LEU B 2 152 ? -2.178  -16.206 9.266   1   51.41  ? 148 LEU A CD2 1 
ATOM   3334 N N   . ALA B 2 153 ? -8.214  -15.871 8.747   1   40.2   ? 149 ALA A N   1 
ATOM   3335 C CA  . ALA B 2 153 ? -9.376  -16.201 7.902   1   37.17  ? 149 ALA A CA  1 
ATOM   3336 C C   . ALA B 2 153 ? -9.746  -15.04  6.988   1   37.06  ? 149 ALA A C   1 
ATOM   3337 O O   . ALA B 2 153 ? -9.287  -13.917 7.218   1   36.72  ? 149 ALA A O   1 
ATOM   3338 C CB  . ALA B 2 153 ? -10.514 -16.614 8.791   1   35.16  ? 149 ALA A CB  1 
ATOM   3339 N N   . ARG B 2 154 ? -10.547 -15.333 5.969   1   36.35  ? 150 ARG A N   1 
ATOM   3340 C CA  . ARG B 2 154 ? -10.913 -14.292 4.986   1   39.23  ? 150 ARG A CA  1 
ATOM   3341 C C   . ARG B 2 154 ? -12.335 -14.511 4.472   1   39.96  ? 150 ARG A C   1 
ATOM   3342 O O   . ARG B 2 154 ? -12.679 -15.656 4.143   1   38.46  ? 150 ARG A O   1 
ATOM   3343 C CB  . ARG B 2 154 ? -9.979  -14.289 3.773   1   40.06  ? 150 ARG A CB  1 
ATOM   3344 C CG  . ARG B 2 154 ? -10.189 -13.179 2.756   1   42.67  ? 150 ARG A CG  1 
ATOM   3345 C CD  . ARG B 2 154 ? -9.351  -11.98  3.131   1   46.82  ? 150 ARG A CD  1 
ATOM   3346 N NE  . ARG B 2 154 ? -8.574  -11.5   1.986   1   46     ? 150 ARG A NE  1 
ATOM   3347 C CZ  . ARG B 2 154 ? -8.721  -10.303 1.453   1   46.88  ? 150 ARG A CZ  1 
ATOM   3348 N NH1 . ARG B 2 154 ? -7.66   -9.582  1.148   1   44.35  ? 150 ARG A NH1 1 
ATOM   3349 N NH2 . ARG B 2 154 ? -9.931  -9.828  1.233   1   48.28  ? 150 ARG A NH2 1 
ATOM   3350 N N   . ALA B 2 155 ? -13.121 -13.438 4.423   1   38.6   ? 151 ALA A N   1 
ATOM   3351 C CA  . ALA B 2 155 ? -14.461 -13.521 3.818   1   38.69  ? 151 ALA A CA  1 
ATOM   3352 C C   . ALA B 2 155 ? -14.293 -13.426 2.309   1   39.95  ? 151 ALA A C   1 
ATOM   3353 O O   . ALA B 2 155 ? -13.802 -12.405 1.821   1   45.47  ? 151 ALA A O   1 
ATOM   3354 C CB  . ALA B 2 155 ? -15.318 -12.41  4.324   1   40.68  ? 151 ALA A CB  1 
ATOM   3355 N N   . PHE B 2 156 ? -14.686 -14.473 1.602   1   37.7   ? 152 PHE A N   1 
ATOM   3356 C CA  . PHE B 2 156 ? -14.473 -14.465 0.165   1   37.3   ? 152 PHE A CA  1 
ATOM   3357 C C   . PHE B 2 156 ? -15.728 -14.047 -0.598  1   40.8   ? 152 PHE A C   1 
ATOM   3358 O O   . PHE B 2 156 ? -16.855 -14.049 -0.064  1   42.49  ? 152 PHE A O   1 
ATOM   3359 C CB  . PHE B 2 156 ? -13.853 -15.758 -0.338  1   35.2   ? 152 PHE A CB  1 
ATOM   3360 C CG  . PHE B 2 156 ? -14.647 -17.039 -0.14   1   35.49  ? 152 PHE A CG  1 
ATOM   3361 C CD1 . PHE B 2 156 ? -14.55  -17.762 1.058   1   34.07  ? 152 PHE A CD1 1 
ATOM   3362 C CD2 . PHE B 2 156 ? -15.462 -17.54  -1.168  1   34.94  ? 152 PHE A CD2 1 
ATOM   3363 C CE1 . PHE B 2 156 ? -15.234 -18.975 1.222   1   32.99  ? 152 PHE A CE1 1 
ATOM   3364 C CE2 . PHE B 2 156 ? -16.127 -18.757 -1.014  1   35.19  ? 152 PHE A CE2 1 
ATOM   3365 C CZ  . PHE B 2 156 ? -16.025 -19.47  0.189   1   34.01  ? 152 PHE A CZ  1 
ATOM   3366 N N   . GLY B 2 157 ? -15.476 -13.579 -1.834  1   41.36  ? 153 GLY A N   1 
ATOM   3367 C CA  . GLY B 2 157 ? -16.488 -13.317 -2.842  1   40.45  ? 153 GLY A CA  1 
ATOM   3368 C C   . GLY B 2 157 ? -16.537 -14.492 -3.827  1   40.55  ? 153 GLY A C   1 
ATOM   3369 O O   . GLY B 2 157 ? -15.611 -15.316 -3.893  1   38.08  ? 153 GLY A O   1 
ATOM   3370 N N   . VAL B 2 158 ? -17.613 -14.543 -4.632  1   40.56  ? 154 VAL A N   1 
ATOM   3371 C CA  . VAL B 2 158 ? -17.789 -15.634 -5.581  1   40.18  ? 154 VAL A CA  1 
ATOM   3372 C C   . VAL B 2 158 ? -17.943 -15.029 -6.971  1   40.48  ? 154 VAL A C   1 
ATOM   3373 O O   . VAL B 2 158 ? -18.87  -14.219 -7.142  1   40.74  ? 154 VAL A O   1 
ATOM   3374 C CB  . VAL B 2 158 ? -19.031 -16.473 -5.218  1   40.22  ? 154 VAL A CB  1 
ATOM   3375 C CG1 . VAL B 2 158 ? -19.295 -17.565 -6.261  1   39.82  ? 154 VAL A CG1 1 
ATOM   3376 C CG2 . VAL B 2 158 ? -18.916 -17.062 -3.824  1   37.95  ? 154 VAL A CG2 1 
ATOM   3377 N N   . PRO B 2 159 ? -17.04  -15.331 -7.956  1   39.08  ? 155 PRO A N   1 
ATOM   3378 C CA  . PRO B 2 159 ? -15.819 -16.109 -7.739  1   39.61  ? 155 PRO A CA  1 
ATOM   3379 C C   . PRO B 2 159 ? -14.782 -15.411 -6.856  1   41.04  ? 155 PRO A C   1 
ATOM   3380 O O   . PRO B 2 159 ? -14.852 -14.199 -6.665  1   43.44  ? 155 PRO A O   1 
ATOM   3381 C CB  . PRO B 2 159 ? -15.221 -16.338 -9.143  1   38.55  ? 155 PRO A CB  1 
ATOM   3382 C CG  . PRO B 2 159 ? -15.906 -15.399 -10.081 1   39.84  ? 155 PRO A CG  1 
ATOM   3383 C CD  . PRO B 2 159 ? -17.134 -14.861 -9.342  1   40.94  ? 155 PRO A CD  1 
ATOM   3384 N N   . VAL B 2 160 ? -13.804 -16.172 -6.396  1   41.47  ? 156 VAL A N   1 
ATOM   3385 C CA  . VAL B 2 160 ? -12.782 -15.609 -5.477  1   41.95  ? 156 VAL A CA  1 
ATOM   3386 C C   . VAL B 2 160 ? -11.872 -14.643 -6.24   1   44.05  ? 156 VAL A C   1 
ATOM   3387 O O   . VAL B 2 160 ? -11.759 -14.762 -7.466  1   43.92  ? 156 VAL A O   1 
ATOM   3388 C CB  . VAL B 2 160 ? -11.988 -16.743 -4.806  1   41.09  ? 156 VAL A CB  1 
ATOM   3389 C CG1 . VAL B 2 160 ? -12.872 -17.615 -3.927  1   38.8   ? 156 VAL A CG1 1 
ATOM   3390 C CG2 . VAL B 2 160 ? -11.235 -17.585 -5.825  1   41.29  ? 156 VAL A CG2 1 
ATOM   3391 N N   . ARG B 2 161 ? -11.296 -13.69  -5.525  1   46.36  ? 157 ARG A N   1 
ATOM   3392 C CA  . ARG B 2 161 ? -10.325 -12.762 -6.141  1   51.47  ? 157 ARG A CA  1 
ATOM   3393 C C   . ARG B 2 161 ? -8.946  -13.14  -5.58   1   47.43  ? 157 ARG A C   1 
ATOM   3394 O O   . ARG B 2 161 ? -8.863  -14.125 -4.833  1   43     ? 157 ARG A O   1 
ATOM   3395 C CB  . ARG B 2 161 ? -10.766 -11.319 -5.871  1   53.88  ? 157 ARG A CB  1 
ATOM   3396 C CG  . ARG B 2 161 ? -10.365 -10.687 -4.55   1   55.26  ? 157 ARG A CG  1 
ATOM   3397 C CD  . ARG B 2 161 ? -10.556 -9.185  -4.559  1   69.53  ? 157 ARG A CD  1 
ATOM   3398 N NE  . ARG B 2 161 ? -10.672 -8.641  -3.202  1   78.84  ? 157 ARG A NE  1 
ATOM   3399 C CZ  . ARG B 2 161 ? -9.653  -8.398  -2.39   1   77.96  ? 157 ARG A CZ  1 
ATOM   3400 N NH1 . ARG B 2 161 ? -9.859  -7.741  -1.271  1   76.12  ? 157 ARG A NH1 1 
ATOM   3401 N NH2 . ARG B 2 161 ? -8.432  -8.8    -2.691  1   78.26  ? 157 ARG A NH2 1 
ATOM   3402 N N   . THR B 2 162 ? -7.911  -12.397 -5.954  1   48.69  ? 158 THR A N   1 
ATOM   3403 C CA  . THR B 2 162 ? -6.556  -12.703 -5.473  1   47.5   ? 158 THR A CA  1 
ATOM   3404 C C   . THR B 2 162 ? -6.454  -12.283 -4.033  1   43.36  ? 158 THR A C   1 
ATOM   3405 O O   . THR B 2 162 ? -6.74   -11.115 -3.737  1   44.2   ? 158 THR A O   1 
ATOM   3406 C CB  . THR B 2 162 ? -5.506  -12.016 -6.34   1   53.31  ? 158 THR A CB  1 
ATOM   3407 O OG1 . THR B 2 162 ? -5.671  -12.597 -7.628  1   63.44  ? 158 THR A OG1 1 
ATOM   3408 C CG2 . THR B 2 162 ? -4.094  -12.242 -5.833  1   48.06  ? 158 THR A CG2 1 
ATOM   3409 N N   . TYR B 2 163 ? -6.091  -13.216 -3.162  1   40.49  ? 159 TYR A N   1 
ATOM   3410 C CA  . TYR B 2 163 ? -5.865  -12.831 -1.767  1   42.28  ? 159 TYR A CA  1 
ATOM   3411 C C   . TYR B 2 163 ? -4.384  -13.018 -1.388  1   42.61  ? 159 TYR A C   1 
ATOM   3412 O O   . TYR B 2 163 ? -3.543  -13.364 -2.226  1   43.06  ? 159 TYR A O   1 
ATOM   3413 C CB  . TYR B 2 163 ? -6.804  -13.601 -0.835  1   43.12  ? 159 TYR A CB  1 
ATOM   3414 C CG  . TYR B 2 163 ? -8.272  -13.608 -1.233  1   46.49  ? 159 TYR A CG  1 
ATOM   3415 C CD1 . TYR B 2 163 ? -8.986  -12.426 -1.397  1   48.22  ? 159 TYR A CD1 1 
ATOM   3416 C CD2 . TYR B 2 163 ? -8.94   -14.808 -1.458  1   48.12  ? 159 TYR A CD2 1 
ATOM   3417 C CE1 . TYR B 2 163 ? -10.32  -12.447 -1.765  1   49.84  ? 159 TYR A CE1 1 
ATOM   3418 C CE2 . TYR B 2 163 ? -10.278 -14.837 -1.82   1   48.68  ? 159 TYR A CE2 1 
ATOM   3419 C CZ  . TYR B 2 163 ? -10.974 -13.652 -1.978  1   50.41  ? 159 TYR A CZ  1 
ATOM   3420 O OH  . TYR B 2 163 ? -12.297 -13.675 -2.374  1   51.27  ? 159 TYR A OH  1 
HETATM 3421 N N   . TPO B 2 164 ? -4.079  -12.764 -0.123  1   41.04  ? 160 TPO A N   1 
HETATM 3422 C CA  . TPO B 2 164 ? -2.741  -12.841 0.421   1   44.41  ? 160 TPO A CA  1 
HETATM 3423 C CB  . TPO B 2 164 ? -2.793  -12.673 1.953   1   44.1   ? 160 TPO A CB  1 
HETATM 3424 C CG2 . TPO B 2 164 ? -1.424  -12.565 2.596   1   42.22  ? 160 TPO A CG2 1 
HETATM 3425 O OG1 . TPO B 2 164 ? -3.473  -11.397 2.206   1   44.92  ? 160 TPO A OG1 1 
HETATM 3426 P P   . TPO B 2 164 ? -4.918  -11.396 2.963   1   40.68  ? 160 TPO A P   1 
HETATM 3427 O O1P . TPO B 2 164 ? -5.846  -12.19  2.101   1   38.21  ? 160 TPO A O1P 1 
HETATM 3428 O O2P . TPO B 2 164 ? -5.242  -9.941  3.149   1   40.02  ? 160 TPO A O2P 1 
HETATM 3429 O O3P . TPO B 2 164 ? -4.741  -12.141 4.259   1   40.83  ? 160 TPO A O3P 1 
HETATM 3430 C C   . TPO B 2 164 ? -2.098  -14.153 -0.019  1   44.36  ? 160 TPO A C   1 
HETATM 3431 O O   . TPO B 2 164 ? -2.7    -15.211 0.134   1   42.4   ? 160 TPO A O   1 
ATOM   3432 N N   . HIS B 2 165 ? -0.863  -14.063 -0.526  1   49.8   ? 161 HIS A N   1 
ATOM   3433 C CA  . HIS B 2 165 ? -0.12   -15.237 -0.966  1   55.75  ? 161 HIS A CA  1 
ATOM   3434 C C   . HIS B 2 165 ? 0.516   -15.994 0.198   1   56.95  ? 161 HIS A C   1 
ATOM   3435 O O   . HIS B 2 165 ? 0.618   -17.219 0.194   1   60.99  ? 161 HIS A O   1 
ATOM   3436 C CB  . HIS B 2 165 ? 0.892   -14.904 -2.068  1   61.54  ? 161 HIS A CB  1 
ATOM   3437 C CG  . HIS B 2 165 ? 1.675   -16.122 -2.472  1   86.93  ? 161 HIS A CG  1 
ATOM   3438 N ND1 . HIS B 2 165 ? 3.032   -16.09  -2.752  1   105.11 ? 161 HIS A ND1 1 
ATOM   3439 C CD2 . HIS B 2 165 ? 1.306   -17.417 -2.604  1   75.57  ? 161 HIS A CD2 1 
ATOM   3440 C CE1 . HIS B 2 165 ? 3.455   -17.313 -3.06   1   96.26  ? 161 HIS A CE1 1 
ATOM   3441 N NE2 . HIS B 2 165 ? 2.424   -18.134 -2.956  1   86.52  ? 161 HIS A NE2 1 
ATOM   3442 N N   . GLU B 2 166 ? 1.014   -15.274 1.196   1   73.34  ? 162 GLU A N   1 
ATOM   3443 C CA  . GLU B 2 166 ? 1.812   -15.957 2.215   1   92.14  ? 162 GLU A CA  1 
ATOM   3444 C C   . GLU B 2 166 ? 0.841   -16.558 3.23    1   80.79  ? 162 GLU A C   1 
ATOM   3445 O O   . GLU B 2 166 ? 0.659   -15.934 4.288   1   77.3   ? 162 GLU A O   1 
ATOM   3446 C CB  . GLU B 2 166 ? 2.832   -15.067 2.952   1   111.78 ? 162 GLU A CB  1 
ATOM   3447 C CG  . GLU B 2 166 ? 3.559   -14.029 2.095   1   131.9  ? 162 GLU A CG  1 
ATOM   3448 C CD  . GLU B 2 166 ? 2.881   -12.669 1.939   1   137.38 ? 162 GLU A CD  1 
ATOM   3449 O OE1 . GLU B 2 166 ? 2.367   -12.331 0.846   1   121    ? 162 GLU A OE1 1 
ATOM   3450 O OE2 . GLU B 2 166 ? 2.859   -11.934 2.947   1   139.56 ? 162 GLU A OE2 1 
ATOM   3451 N N   . VAL B 2 167 ? 0.183   -17.7   2.874   1   62.94  ? 163 VAL A N   1 
ATOM   3452 C CA  . VAL B 2 167 ? -0.951  -18.198 3.673   1   50.44  ? 163 VAL A CA  1 
ATOM   3453 C C   . VAL B 2 167 ? -0.844  -19.698 3.907   1   45.39  ? 163 VAL A C   1 
ATOM   3454 O O   . VAL B 2 167 ? -0.51   -20.443 2.981   1   45.18  ? 163 VAL A O   1 
ATOM   3455 C CB  . VAL B 2 167 ? -2.387  -17.865 3.217   1   44.26  ? 163 VAL A CB  1 
ATOM   3456 C CG1 . VAL B 2 167 ? -2.607  -16.368 3.17    1   42.58  ? 163 VAL A CG1 1 
ATOM   3457 C CG2 . VAL B 2 167 ? -2.784  -18.533 1.898   1   40.48  ? 163 VAL A CG2 1 
ATOM   3458 N N   . VAL B 2 168 ? -1.17   -20.092 5.147   1   40.13  ? 164 VAL A N   1 
ATOM   3459 C CA  . VAL B 2 168 ? -1.228  -21.463 5.615   1   37.59  ? 164 VAL A CA  1 
ATOM   3460 C C   . VAL B 2 168 ? 0.178   -21.875 6.079   1   42.25  ? 164 VAL A C   1 
ATOM   3461 O O   . VAL B 2 168 ? 1.176   -21.706 5.352   1   40.46  ? 164 VAL A O   1 
ATOM   3462 C CB  . VAL B 2 168 ? -1.817  -22.472 4.609   1   35.52  ? 164 VAL A CB  1 
ATOM   3463 C CG1 . VAL B 2 168 ? -2.082  -23.8   5.289   1   35.03  ? 164 VAL A CG1 1 
ATOM   3464 C CG2 . VAL B 2 168 ? -3.067  -21.976 3.868   1   32.02  ? 164 VAL A CG2 1 
ATOM   3465 N N   . THR B 2 169 ? 0.259   -22.392 7.32    1   41.8   ? 165 THR A N   1 
ATOM   3466 C CA  . THR B 2 169 ? 1.479   -23.016 7.818   1   40.95  ? 165 THR A CA  1 
ATOM   3467 C C   . THR B 2 169 ? 1.994   -24.027 6.784   1   42.94  ? 165 THR A C   1 
ATOM   3468 O O   . THR B 2 169 ? 1.245   -24.885 6.255   1   39.38  ? 165 THR A O   1 
ATOM   3469 C CB  . THR B 2 169 ? 1.229   -23.659 9.179   1   40.39  ? 165 THR A CB  1 
ATOM   3470 O OG1 . THR B 2 169 ? 0.786   -22.567 9.984   1   41.96  ? 165 THR A OG1 1 
ATOM   3471 C CG2 . THR B 2 169 ? 2.497   -24.25  9.782   1   38.65  ? 165 THR A CG2 1 
ATOM   3472 N N   . LEU B 2 170 ? 3.307   -23.898 6.507   1   43.36  ? 166 LEU A N   1 
ATOM   3473 C CA  . LEU B 2 170 ? 3.93    -24.486 5.334   1   40.3   ? 166 LEU A CA  1 
ATOM   3474 C C   . LEU B 2 170 ? 3.543   -25.953 5.195   1   37.72  ? 166 LEU A C   1 
ATOM   3475 O O   . LEU B 2 170 ? 3.213   -26.398 4.105   1   37.8   ? 166 LEU A O   1 
ATOM   3476 C CB  . LEU B 2 170 ? 5.449   -24.332 5.466   1   43.26  ? 166 LEU A CB  1 
ATOM   3477 C CG  . LEU B 2 170 ? 6.279   -24.918 4.316   1   42.08  ? 166 LEU A CG  1 
ATOM   3478 C CD1 . LEU B 2 170 ? 5.865   -24.245 2.998   1   40.84  ? 166 LEU A CD1 1 
ATOM   3479 C CD2 . LEU B 2 170 ? 7.794   -24.71  4.56    1   41.56  ? 166 LEU A CD2 1 
ATOM   3480 N N   . TRP B 2 171 ? 3.668   -26.728 6.281   1   37.5   ? 167 TRP A N   1 
ATOM   3481 C CA  . TRP B 2 171 ? 3.46    -28.171 6.17    1   37.89  ? 167 TRP A CA  1 
ATOM   3482 C C   . TRP B 2 171 ? 2.047   -28.511 5.687   1   40.24  ? 167 TRP A C   1 
ATOM   3483 O O   . TRP B 2 171 ? 1.807   -29.632 5.222   1   39.46  ? 167 TRP A O   1 
ATOM   3484 C CB  . TRP B 2 171 ? 3.712   -28.884 7.501   1   36.74  ? 167 TRP A CB  1 
ATOM   3485 C CG  . TRP B 2 171 ? 5.132   -28.838 7.967   1   39.69  ? 167 TRP A CG  1 
ATOM   3486 C CD1 . TRP B 2 171 ? 6.229   -28.378 7.286   1   40.94  ? 167 TRP A CD1 1 
ATOM   3487 C CD2 . TRP B 2 171 ? 5.605   -29.31  9.239   1   40.25  ? 167 TRP A CD2 1 
ATOM   3488 N NE1 . TRP B 2 171 ? 7.349   -28.494 8.068   1   41.99  ? 167 TRP A NE1 1 
ATOM   3489 C CE2 . TRP B 2 171 ? 7.002   -29.062 9.27    1   42.86  ? 167 TRP A CE2 1 
ATOM   3490 C CE3 . TRP B 2 171 ? 4.992   -29.909 10.341  1   40.77  ? 167 TRP A CE3 1 
ATOM   3491 C CZ2 . TRP B 2 171 ? 7.795   -29.41  10.369  1   42.92  ? 167 TRP A CZ2 1 
ATOM   3492 C CZ3 . TRP B 2 171 ? 5.781   -30.257 11.421  1   42.75  ? 167 TRP A CZ3 1 
ATOM   3493 C CH2 . TRP B 2 171 ? 7.161   -30.013 11.435  1   41.68  ? 167 TRP A CH2 1 
ATOM   3494 N N   . TYR B 2 172 ? 1.123   -27.537 5.815   1   37.64  ? 168 TYR A N   1 
ATOM   3495 C CA  . TYR B 2 172 ? -0.294  -27.778 5.568   1   39.14  ? 168 TYR A CA  1 
ATOM   3496 C C   . TYR B 2 172 ? -0.744  -27.018 4.313   1   39.2   ? 168 TYR A C   1 
ATOM   3497 O O   . TYR B 2 172 ? -1.931  -27.006 4.009   1   40.37  ? 168 TYR A O   1 
ATOM   3498 C CB  . TYR B 2 172 ? -1.108  -27.481 6.844   1   34.62  ? 168 TYR A CB  1 
ATOM   3499 C CG  . TYR B 2 172 ? -0.662  -28.305 8.041   1   34.91  ? 168 TYR A CG  1 
ATOM   3500 C CD1 . TYR B 2 172 ? -1.116  -29.613 8.236   1   34.51  ? 168 TYR A CD1 1 
ATOM   3501 C CD2 . TYR B 2 172 ? 0.326   -27.816 8.907   1   34.96  ? 168 TYR A CD2 1 
ATOM   3502 C CE1 . TYR B 2 172 ? -0.651  -30.388 9.302   1   34.4   ? 168 TYR A CE1 1 
ATOM   3503 C CE2 . TYR B 2 172 ? 0.783   -28.571 9.976   1   33.61  ? 168 TYR A CE2 1 
ATOM   3504 C CZ  . TYR B 2 172 ? 0.293   -29.852 10.177  1   34.04  ? 168 TYR A CZ  1 
ATOM   3505 O OH  . TYR B 2 172 ? 0.794   -30.561 11.234  1   34.12  ? 168 TYR A OH  1 
ATOM   3506 N N   . ARG B 2 173 ? 0.2     -26.397 3.588   1   38.35  ? 169 ARG A N   1 
ATOM   3507 C CA  . ARG B 2 173 ? -0.13   -25.521 2.47    1   37.83  ? 169 ARG A CA  1 
ATOM   3508 C C   . ARG B 2 173 ? -0.378  -26.3   1.175   1   38.56  ? 169 ARG A C   1 
ATOM   3509 O O   . ARG B 2 173 ? 0.375   -27.233 0.85    1   39.67  ? 169 ARG A O   1 
ATOM   3510 C CB  . ARG B 2 173 ? 1.046   -24.574 2.255   1   35.94  ? 169 ARG A CB  1 
ATOM   3511 C CG  . ARG B 2 173 ? 0.735   -23.409 1.333   1   36.8   ? 169 ARG A CG  1 
ATOM   3512 C CD  . ARG B 2 173 ? 1.862   -22.401 1.317   1   37.36  ? 169 ARG A CD  1 
ATOM   3513 N NE  . ARG B 2 173 ? 2.192   -21.906 2.667   1   39.19  ? 169 ARG A NE  1 
ATOM   3514 C CZ  . ARG B 2 173 ? 3.285   -21.193 2.951   1   44.24  ? 169 ARG A CZ  1 
ATOM   3515 N NH1 . ARG B 2 173 ? 4.183   -20.883 2.001   1   41.56  ? 169 ARG A NH1 1 
ATOM   3516 N NH2 . ARG B 2 173 ? 3.528   -20.86  4.207   1   44.83  ? 169 ARG A NH2 1 
ATOM   3517 N N   . ALA B 2 174 ? -1.433  -25.899 0.434   1   35.61  ? 170 ALA A N   1 
ATOM   3518 C CA  . ALA B 2 174 ? -1.812  -26.563 -0.816  1   35.49  ? 170 ALA A CA  1 
ATOM   3519 C C   . ALA B 2 174 ? -0.82   -26.293 -1.945  1   36.04  ? 170 ALA A C   1 
ATOM   3520 O O   . ALA B 2 174 ? -0.244  -25.218 -2.053  1   38.92  ? 170 ALA A O   1 
ATOM   3521 C CB  . ALA B 2 174 ? -3.186  -26.129 -1.275  1   31.86  ? 170 ALA A CB  1 
ATOM   3522 N N   . PRO B 2 175 ? -0.691  -27.217 -2.914  1   38.96  ? 171 PRO A N   1 
ATOM   3523 C CA  . PRO B 2 175 ? 0.268   -27.033 -4.01   1   40.56  ? 171 PRO A CA  1 
ATOM   3524 C C   . PRO B 2 175 ? 0.032   -25.76  -4.818  1   41.09  ? 171 PRO A C   1 
ATOM   3525 O O   . PRO B 2 175 ? 1.003   -25.136 -5.253  1   38.97  ? 171 PRO A O   1 
ATOM   3526 C CB  . PRO B 2 175 ? 0.168   -28.33  -4.841  1   38.64  ? 171 PRO A CB  1 
ATOM   3527 C CG  . PRO B 2 175 ? -1.141  -28.929 -4.405  1   35.52  ? 171 PRO A CG  1 
ATOM   3528 C CD  . PRO B 2 175 ? -1.397  -28.503 -2.977  1   35.7   ? 171 PRO A CD  1 
ATOM   3529 N N   . GLU B 2 176 ? -1.248  -25.366 -4.963  1   39.07  ? 172 GLU A N   1 
ATOM   3530 C CA  . GLU B 2 176 ? -1.602  -24.22  -5.773  1   37.94  ? 172 GLU A CA  1 
ATOM   3531 C C   . GLU B 2 176 ? -1.107  -22.934 -5.11   1   40.11  ? 172 GLU A C   1 
ATOM   3532 O O   . GLU B 2 176 ? -0.747  -21.981 -5.813  1   42.29  ? 172 GLU A O   1 
ATOM   3533 C CB  . GLU B 2 176 ? -3.098  -24.182 -6.116  1   37.28  ? 172 GLU A CB  1 
ATOM   3534 C CG  . GLU B 2 176 ? -4.07   -24.14  -4.943  1   37.07  ? 172 GLU A CG  1 
ATOM   3535 C CD  . GLU B 2 176 ? -4.586  -25.443 -4.344  1   37.42  ? 172 GLU A CD  1 
ATOM   3536 O OE1 . GLU B 2 176 ? -5.715  -25.469 -3.775  1   38.33  ? 172 GLU A OE1 1 
ATOM   3537 O OE2 . GLU B 2 176 ? -3.868  -26.439 -4.439  1   38.89  ? 172 GLU A OE2 1 
ATOM   3538 N N   . ILE B 2 177 ? -1.077  -22.888 -3.767  1   37.44  ? 173 ILE A N   1 
ATOM   3539 C CA  . ILE B 2 177 ? -0.453  -21.733 -3.114  1   38.63  ? 173 ILE A CA  1 
ATOM   3540 C C   . ILE B 2 177 ? 1.058   -21.774 -3.359  1   38.26  ? 173 ILE A C   1 
ATOM   3541 O O   . ILE B 2 177 ? 1.668   -20.803 -3.815  1   38.5   ? 173 ILE A O   1 
ATOM   3542 C CB  . ILE B 2 177 ? -0.805  -21.688 -1.614  1   38.64  ? 173 ILE A CB  1 
ATOM   3543 C CG1 . ILE B 2 177 ? -2.351  -21.675 -1.423  1   37.87  ? 173 ILE A CG1 1 
ATOM   3544 C CG2 . ILE B 2 177 ? -0.156  -20.484 -0.926  1   36.38  ? 173 ILE A CG2 1 
ATOM   3545 C CD1 . ILE B 2 177 ? -2.802  -21.985 -0.01   1   36.64  ? 173 ILE A CD1 1 
ATOM   3546 N N   . LEU B 2 178 ? 1.659   -22.931 -3.106  1   37.14  ? 174 LEU A N   1 
ATOM   3547 C CA  . LEU B 2 178 ? 3.1     -23.085 -3.317  1   40.23  ? 174 LEU A CA  1 
ATOM   3548 C C   . LEU B 2 178 ? 3.511   -22.702 -4.743  1   42.07  ? 174 LEU A C   1 
ATOM   3549 O O   . LEU B 2 178 ? 4.602   -22.185 -4.92   1   45.48  ? 174 LEU A O   1 
ATOM   3550 C CB  . LEU B 2 178 ? 3.474   -24.524 -2.987  1   37.53  ? 174 LEU A CB  1 
ATOM   3551 C CG  . LEU B 2 178 ? 3.447   -24.882 -1.499  1   34.85  ? 174 LEU A CG  1 
ATOM   3552 C CD1 . LEU B 2 178 ? 3.56    -26.377 -1.306  1   32.8   ? 174 LEU A CD1 1 
ATOM   3553 C CD2 . LEU B 2 178 ? 4.614   -24.192 -0.881  1   35.12  ? 174 LEU A CD2 1 
ATOM   3554 N N   . LEU B 2 179 ? 2.623   -22.877 -5.749  1   40.62  ? 175 LEU A N   1 
ATOM   3555 C CA  . LEU B 2 179 ? 2.957   -22.573 -7.136  1   41.96  ? 175 LEU A CA  1 
ATOM   3556 C C   . LEU B 2 179 ? 2.55    -21.144 -7.505  1   43.33  ? 175 LEU A C   1 
ATOM   3557 O O   . LEU B 2 179 ? 2.52    -20.762 -8.683  1   46     ? 175 LEU A O   1 
ATOM   3558 C CB  . LEU B 2 179 ? 2.284   -23.583 -8.067  1   39.64  ? 175 LEU A CB  1 
ATOM   3559 C CG  . LEU B 2 179 ? 2.827   -25.009 -7.998  1   38.71  ? 175 LEU A CG  1 
ATOM   3560 C CD1 . LEU B 2 179 ? 1.988   -25.882 -8.878  1   38.77  ? 175 LEU A CD1 1 
ATOM   3561 C CD2 . LEU B 2 179 ? 4.299   -25.084 -8.361  1   37.61  ? 175 LEU A CD2 1 
ATOM   3562 N N   . GLY B 2 180 ? 2.222   -20.342 -6.498  1   41.15  ? 176 GLY A N   1 
ATOM   3563 C CA  . GLY B 2 180 ? 1.963   -18.936 -6.741  1   41.26  ? 176 GLY A CA  1 
ATOM   3564 C C   . GLY B 2 180 ? 0.682   -18.661 -7.545  1   40.54  ? 176 GLY A C   1 
ATOM   3565 O O   . GLY B 2 180 ? 0.589   -17.594 -8.178  1   41.76  ? 176 GLY A O   1 
ATOM   3566 N N   A CYS B 2 181 ? -0.259  -19.618 -7.587  0.5 37.82  ? 177 CYS A N   1 
ATOM   3567 N N   B CYS B 2 181 ? -0.311  -19.559 -7.406  0.5 37.4   ? 177 CYS A N   1 
ATOM   3568 C CA  A CYS B 2 181 ? -1.458  -19.426 -8.396  0.5 38.48  ? 177 CYS A CA  1 
ATOM   3569 C CA  B CYS B 2 181 ? -1.625  -19.406 -8.019  0.5 37.59  ? 177 CYS A CA  1 
ATOM   3570 C C   A CYS B 2 181 ? -2.126  -18.118 -7.965  0.5 38.88  ? 177 CYS A C   1 
ATOM   3571 C C   B CYS B 2 181 ? -2.077  -17.952 -7.892  0.5 38.51  ? 177 CYS A C   1 
ATOM   3572 O O   A CYS B 2 181 ? -2.094  -17.747 -6.79   0.5 39.11  ? 177 CYS A O   1 
ATOM   3573 O O   B CYS B 2 181 ? -1.846  -17.32  -6.861  0.5 39.12  ? 177 CYS A O   1 
ATOM   3574 C CB  A CYS B 2 181 ? -2.374  -20.654 -8.396  0.5 36.08  ? 177 CYS A CB  1 
ATOM   3575 C CB  B CYS B 2 181 ? -2.667  -20.345 -7.401  0.5 34.09  ? 177 CYS A CB  1 
ATOM   3576 S SG  A CYS B 2 181 ? -1.85   -22.023 -9.476  0.5 33.66  ? 177 CYS A SG  1 
ATOM   3577 S SG  B CYS B 2 181 ? -2.981  -20.084 -5.635  0.5 31.49  ? 177 CYS A SG  1 
ATOM   3578 N N   . LYS B 2 182 ? -2.695  -17.423 -8.955  1   39.91  ? 178 LYS A N   1 
ATOM   3579 C CA  . LYS B 2 182 ? -3.347  -16.124 -8.839  1   43.7   ? 178 LYS A CA  1 
ATOM   3580 C C   . LYS B 2 182 ? -4.597  -16.216 -7.952  1   41.34  ? 178 LYS A C   1 
ATOM   3581 O O   . LYS B 2 182 ? -4.953  -15.256 -7.281  1   41.82  ? 178 LYS A O   1 
ATOM   3582 C CB  . LYS B 2 182 ? -3.636  -15.664 -10.275 1   49.84  ? 178 LYS A CB  1 
ATOM   3583 C CG  . LYS B 2 182 ? -4.424  -14.371 -10.414 1   60.35  ? 178 LYS A CG  1 
ATOM   3584 C CD  . LYS B 2 182 ? -4.73   -13.949 -11.85  1   69.64  ? 178 LYS A CD  1 
ATOM   3585 C CE  . LYS B 2 182 ? -5.044  -12.458 -11.874 1   78.49  ? 178 LYS A CE  1 
ATOM   3586 N NZ  . LYS B 2 182 ? -5.901  -11.962 -12.959 1   76.19  ? 178 LYS A NZ  1 
ATOM   3587 N N   . TYR B 2 183 ? -5.253  -17.379 -7.96   1   39.41  ? 179 TYR A N   1 
ATOM   3588 C CA  . TYR B 2 183 ? -6.482  -17.559 -7.221  1   41.54  ? 179 TYR A CA  1 
ATOM   3589 C C   . TYR B 2 183 ? -6.438  -18.872 -6.479  1   40.32  ? 179 TYR A C   1 
ATOM   3590 O O   . TYR B 2 183 ? -5.971  -19.855 -7.028  1   42.28  ? 179 TYR A O   1 
ATOM   3591 C CB  . TYR B 2 183 ? -7.647  -17.765 -8.185  1   41.29  ? 179 TYR A CB  1 
ATOM   3592 C CG  . TYR B 2 183 ? -7.937  -16.581 -9.094  1   43.33  ? 179 TYR A CG  1 
ATOM   3593 C CD1 . TYR B 2 183 ? -8.322  -15.354 -8.549  1   42.35  ? 179 TYR A CD1 1 
ATOM   3594 C CD2 . TYR B 2 183 ? -7.857  -16.711 -10.487 1   44.66  ? 179 TYR A CD2 1 
ATOM   3595 C CE1 . TYR B 2 183 ? -8.633  -14.283 -9.371  1   45.32  ? 179 TYR A CE1 1 
ATOM   3596 C CE2 . TYR B 2 183 ? -8.17   -15.642 -11.317 1   48.05  ? 179 TYR A CE2 1 
ATOM   3597 C CZ  . TYR B 2 183 ? -8.566  -14.437 -10.75  1   49.37  ? 179 TYR A CZ  1 
ATOM   3598 O OH  . TYR B 2 183 ? -8.888  -13.363 -11.524 1   54.03  ? 179 TYR A OH  1 
ATOM   3599 N N   . TYR B 2 184 ? -6.919  -18.851 -5.234  1   40.07  ? 180 TYR A N   1 
ATOM   3600 C CA  . TYR B 2 184 ? -7.194  -20.073 -4.505  1   38.16  ? 180 TYR A CA  1 
ATOM   3601 C C   . TYR B 2 184 ? -8.575  -19.944 -3.851  1   37.42  ? 180 TYR A C   1 
ATOM   3602 O O   . TYR B 2 184 ? -9.123  -18.842 -3.712  1   37.26  ? 180 TYR A O   1 
ATOM   3603 C CB  . TYR B 2 184 ? -6.06   -20.424 -3.537  1   36.32  ? 180 TYR A CB  1 
ATOM   3604 C CG  . TYR B 2 184 ? -5.829  -19.347 -2.478  1   38.4   ? 180 TYR A CG  1 
ATOM   3605 C CD1 . TYR B 2 184 ? -6.714  -19.183 -1.408  1   36.77  ? 180 TYR A CD1 1 
ATOM   3606 C CD2 . TYR B 2 184 ? -4.724  -18.496 -2.547  1   38.49  ? 180 TYR A CD2 1 
ATOM   3607 C CE1 . TYR B 2 184 ? -6.486  -18.211 -0.444  1   37.45  ? 180 TYR A CE1 1 
ATOM   3608 C CE2 . TYR B 2 184 ? -4.485  -17.528 -1.574  1   38.94  ? 180 TYR A CE2 1 
ATOM   3609 C CZ  . TYR B 2 184 ? -5.372  -17.377 -0.52   1   38.37  ? 180 TYR A CZ  1 
ATOM   3610 O OH  . TYR B 2 184 ? -5.171  -16.394 0.408   1   37.79  ? 180 TYR A OH  1 
ATOM   3611 N N   . SER B 2 185 ? -9.106  -21.094 -3.414  1   36.89  ? 181 SER A N   1 
ATOM   3612 C CA  . SER B 2 185 ? -10.478 -21.179 -2.963  1   39.42  ? 181 SER A CA  1 
ATOM   3613 C C   . SER B 2 185 ? -10.579 -22.155 -1.794  1   38.28  ? 181 SER A C   1 
ATOM   3614 O O   . SER B 2 185 ? -9.575  -22.421 -1.115  1   38.11  ? 181 SER A O   1 
ATOM   3615 C CB  . SER B 2 185 ? -11.384 -21.588 -4.125  1   39.3   ? 181 SER A CB  1 
ATOM   3616 O OG  . SER B 2 185 ? -12.741 -21.312 -3.79   1   39.33  ? 181 SER A OG  1 
ATOM   3617 N N   . THR B 2 186 ? -11.771 -22.751 -1.649  1   34.52  ? 182 THR A N   1 
ATOM   3618 C CA  . THR B 2 186 ? -12.129 -23.607 -0.53   1   34.46  ? 182 THR A CA  1 
ATOM   3619 C C   . THR B 2 186 ? -11.207 -24.819 -0.484  1   35.1   ? 182 THR A C   1 
ATOM   3620 O O   . THR B 2 186 ? -10.959 -25.363 0.583   1   38     ? 182 THR A O   1 
ATOM   3621 C CB  . THR B 2 186 ? -13.605 -24.023 -0.632  1   34.15  ? 182 THR A CB  1 
ATOM   3622 O OG1 . THR B 2 186 ? -13.888 -24.569 -1.925  1   33.99  ? 182 THR A OG1 1 
ATOM   3623 C CG2 . THR B 2 186 ? -14.548 -22.858 -0.374  1   31.68  ? 182 THR A CG2 1 
ATOM   3624 N N   . ALA B 2 187 ? -10.715 -25.236 -1.647  1   34.21  ? 183 ALA A N   1 
ATOM   3625 C CA  . ALA B 2 187 ? -9.883  -26.414 -1.771  1   34.99  ? 183 ALA A CA  1 
ATOM   3626 C C   . ALA B 2 187 ? -8.618  -26.322 -0.906  1   38.51  ? 183 ALA A C   1 
ATOM   3627 O O   . ALA B 2 187 ? -8.094  -27.373 -0.525  1   40.64  ? 183 ALA A O   1 
ATOM   3628 C CB  . ALA B 2 187 ? -9.552  -26.639 -3.232  1   32.03  ? 183 ALA A CB  1 
ATOM   3629 N N   . VAL B 2 188 ? -8.113  -25.107 -0.59   1   37.78  ? 184 VAL A N   1 
ATOM   3630 C CA  . VAL B 2 188 ? -6.902  -25.012 0.224   1   35.9   ? 184 VAL A CA  1 
ATOM   3631 C C   . VAL B 2 188 ? -7.175  -25.531 1.653   1   40.32  ? 184 VAL A C   1 
ATOM   3632 O O   . VAL B 2 188 ? -6.296  -26.158 2.279   1   40.76  ? 184 VAL A O   1 
ATOM   3633 C CB  . VAL B 2 188 ? -6.262  -23.615 0.243   1   33.61  ? 184 VAL A CB  1 
ATOM   3634 C CG1 . VAL B 2 188 ? -6.103  -23.002 -1.129  1   31.25  ? 184 VAL A CG1 1 
ATOM   3635 C CG2 . VAL B 2 188 ? -6.975  -22.674 1.189   1   32.96  ? 184 VAL A CG2 1 
ATOM   3636 N N   . ASP B 2 189 ? -8.426  -25.362 2.146   1   37.39  ? 185 ASP A N   1 
ATOM   3637 C CA  . ASP B 2 189 ? -8.763  -25.807 3.493   1   36.13  ? 185 ASP A CA  1 
ATOM   3638 C C   . ASP B 2 189 ? -8.843  -27.328 3.495   1   33.89  ? 185 ASP A C   1 
ATOM   3639 O O   . ASP B 2 189 ? -8.349  -27.976 4.424   1   33.75  ? 185 ASP A O   1 
ATOM   3640 C CB  . ASP B 2 189 ? -9.995  -25.114 4.074   1   36.6   ? 185 ASP A CB  1 
ATOM   3641 C CG  . ASP B 2 189 ? -9.825  -23.658 4.473   1   38.76  ? 185 ASP A CG  1 
ATOM   3642 O OD1 . ASP B 2 189 ? -8.673  -23.285 4.808   1   35.59  ? 185 ASP A OD1 1 
ATOM   3643 O OD2 . ASP B 2 189 ? -10.841 -22.875 4.394   1   41.62  ? 185 ASP A OD2 1 
ATOM   3644 N N   . ILE B 2 190 ? -9.385  -27.871 2.4     1   31.25  ? 186 ILE A N   1 
ATOM   3645 C CA  . ILE B 2 190 ? -9.51   -29.314 2.291   1   31.78  ? 186 ILE A CA  1 
ATOM   3646 C C   . ILE B 2 190 ? -8.111  -29.948 2.281   1   32.58  ? 186 ILE A C   1 
ATOM   3647 O O   . ILE B 2 190 ? -7.845  -30.918 3.018   1   30.68  ? 186 ILE A O   1 
ATOM   3648 C CB  . ILE B 2 190 ? -10.369 -29.703 1.082   1   31.89  ? 186 ILE A CB  1 
ATOM   3649 C CG1 . ILE B 2 190 ? -11.875 -29.389 1.382   1   34.93  ? 186 ILE A CG1 1 
ATOM   3650 C CG2 . ILE B 2 190 ? -10.166 -31.163 0.681   1   28.47  ? 186 ILE A CG2 1 
ATOM   3651 C CD1 . ILE B 2 190 ? -12.49  -30.278 2.454   1   35.23  ? 186 ILE A CD1 1 
ATOM   3652 N N   . TRP B 2 191 ? -7.189  -29.351 1.517   1   33.83  ? 187 TRP A N   1 
ATOM   3653 C CA  . TRP B 2 191 ? -5.82   -29.865 1.512   1   34.35  ? 187 TRP A CA  1 
ATOM   3654 C C   . TRP B 2 191 ? -5.288  -29.971 2.935   1   34.6   ? 187 TRP A C   1 
ATOM   3655 O O   . TRP B 2 191 ? -4.814  -31.02  3.364   1   38.8   ? 187 TRP A O   1 
ATOM   3656 C CB  . TRP B 2 191 ? -4.908  -29.016 0.628   1   35.37  ? 187 TRP A CB  1 
ATOM   3657 C CG  . TRP B 2 191 ? -3.494  -29.539 0.569   1   35.71  ? 187 TRP A CG  1 
ATOM   3658 C CD1 . TRP B 2 191 ? -2.526  -29.273 1.482   1   34.39  ? 187 TRP A CD1 1 
ATOM   3659 C CD2 . TRP B 2 191 ? -2.894  -30.407 -0.42   1   34.99  ? 187 TRP A CD2 1 
ATOM   3660 N NE1 . TRP B 2 191 ? -1.373  -29.918 1.135   1   37.12  ? 187 TRP A NE1 1 
ATOM   3661 C CE2 . TRP B 2 191 ? -1.556  -30.597 -0.035  1   35.6   ? 187 TRP A CE2 1 
ATOM   3662 C CE3 . TRP B 2 191 ? -3.34   -31.013 -1.596  1   34.83  ? 187 TRP A CE3 1 
ATOM   3663 C CZ2 . TRP B 2 191 ? -0.667  -31.378 -0.767  1   35.27  ? 187 TRP A CZ2 1 
ATOM   3664 C CZ3 . TRP B 2 191 ? -2.457  -31.773 -2.331  1   36.57  ? 187 TRP A CZ3 1 
ATOM   3665 C CH2 . TRP B 2 191 ? -1.136  -31.952 -1.923  1   34.52  ? 187 TRP A CH2 1 
ATOM   3666 N N   . SER B 2 192 ? -5.457  -28.912 3.711   1   36.35  ? 188 SER A N   1 
ATOM   3667 C CA  . SER B 2 192 ? -4.949  -28.935 5.081   1   37.31  ? 188 SER A CA  1 
ATOM   3668 C C   . SER B 2 192 ? -5.535  -30.085 5.907   1   37.08  ? 188 SER A C   1 
ATOM   3669 O O   . SER B 2 192 ? -4.814  -30.794 6.612   1   36.86  ? 188 SER A O   1 
ATOM   3670 C CB  . SER B 2 192 ? -5.123  -27.602 5.747   1   38.94  ? 188 SER A CB  1 
ATOM   3671 O OG  . SER B 2 192 ? -4.524  -26.582 4.956   1   41.85  ? 188 SER A OG  1 
ATOM   3672 N N   . LEU B 2 193 ? -6.856  -30.268 5.82    1   36.46  ? 189 LEU A N   1 
ATOM   3673 C CA  . LEU B 2 193 ? -7.555  -31.331 6.527   1   33.89  ? 189 LEU A CA  1 
ATOM   3674 C C   . LEU B 2 193 ? -7.053  -32.701 6.079   1   31.21  ? 189 LEU A C   1 
ATOM   3675 O O   . LEU B 2 193 ? -7.021  -33.647 6.87    1   32.39  ? 189 LEU A O   1 
ATOM   3676 C CB  . LEU B 2 193 ? -9.069  -31.223 6.288   1   34.32  ? 189 LEU A CB  1 
ATOM   3677 C CG  . LEU B 2 193 ? -9.83   -30.246 7.187   1   36.48  ? 189 LEU A CG  1 
ATOM   3678 C CD1 . LEU B 2 193 ? -11.318 -30.634 7.212   1   36.24  ? 189 LEU A CD1 1 
ATOM   3679 C CD2 . LEU B 2 193 ? -9.313  -30.263 8.614   1   37.83  ? 189 LEU A CD2 1 
ATOM   3680 N N   . GLY B 2 194 ? -6.765  -32.85  4.786   1   30.78  ? 190 GLY A N   1 
ATOM   3681 C CA  . GLY B 2 194 ? -6.176  -34.103 4.333   1   33.16  ? 190 GLY A CA  1 
ATOM   3682 C C   . GLY B 2 194 ? -4.831  -34.38  5.03    1   34.18  ? 190 GLY A C   1 
ATOM   3683 O O   . GLY B 2 194 ? -4.586  -35.495 5.552   1   34.8   ? 190 GLY A O   1 
ATOM   3684 N N   . CYS B 2 195 ? -3.973  -33.349 5.074   1   33.74  ? 191 CYS A N   1 
ATOM   3685 C CA  . CYS B 2 195 ? -2.693  -33.52  5.78    1   34.9   ? 191 CYS A CA  1 
ATOM   3686 C C   . CYS B 2 195 ? -2.998  -33.892 7.221   1   35.89  ? 191 CYS A C   1 
ATOM   3687 O O   . CYS B 2 195 ? -2.34   -34.783 7.749   1   36.42  ? 191 CYS A O   1 
ATOM   3688 C CB  . CYS B 2 195 ? -1.878  -32.237 5.776   1   32.6   ? 191 CYS A CB  1 
ATOM   3689 S SG  . CYS B 2 195 ? -1.411  -31.772 4.092   1   36.77  ? 191 CYS A SG  1 
ATOM   3690 N N   . ILE B 2 196 ? -4.046  -33.264 7.813   1   33.27  ? 192 ILE A N   1 
ATOM   3691 C CA  . ILE B 2 196 ? -4.346  -33.493 9.209   1   34.25  ? 192 ILE A CA  1 
ATOM   3692 C C   . ILE B 2 196 ? -4.866  -34.921 9.404   1   36.39  ? 192 ILE A C   1 
ATOM   3693 O O   . ILE B 2 196 ? -4.497  -35.571 10.4    1   35.07  ? 192 ILE A O   1 
ATOM   3694 C CB  . ILE B 2 196 ? -5.263  -32.38  9.745   1   39.31  ? 192 ILE A CB  1 
ATOM   3695 C CG1 . ILE B 2 196 ? -4.454  -31.094 9.846   1   38.1   ? 192 ILE A CG1 1 
ATOM   3696 C CG2 . ILE B 2 196 ? -5.869  -32.762 11.107  1   39.84  ? 192 ILE A CG2 1 
ATOM   3697 C CD1 . ILE B 2 196 ? -5.27   -29.828 9.992   1   39.28  ? 192 ILE A CD1 1 
ATOM   3698 N N   . PHE B 2 197 ? -5.715  -35.42  8.467   1   36.35  ? 193 PHE A N   1 
ATOM   3699 C CA  . PHE B 2 197 ? -6.195  -36.805 8.536   1   34.85  ? 193 PHE A CA  1 
ATOM   3700 C C   . PHE B 2 197 ? -5.003  -37.781 8.546   1   35.95  ? 193 PHE A C   1 
ATOM   3701 O O   . PHE B 2 197 ? -4.9    -38.644 9.414   1   37.09  ? 193 PHE A O   1 
ATOM   3702 C CB  . PHE B 2 197 ? -7.11   -37.017 7.335   1   32.48  ? 193 PHE A CB  1 
ATOM   3703 C CG  . PHE B 2 197 ? -7.677  -38.408 7.125   1   35.06  ? 193 PHE A CG  1 
ATOM   3704 C CD1 . PHE B 2 197 ? -7.732  -39.327 8.174   1   34.64  ? 193 PHE A CD1 1 
ATOM   3705 C CD2 . PHE B 2 197 ? -8.259  -38.752 5.891   1   34.7   ? 193 PHE A CD2 1 
ATOM   3706 C CE1 . PHE B 2 197 ? -8.305  -40.585 7.972   1   36.48  ? 193 PHE A CE1 1 
ATOM   3707 C CE2 . PHE B 2 197 ? -8.826  -40.008 5.695   1   34.54  ? 193 PHE A CE2 1 
ATOM   3708 C CZ  . PHE B 2 197 ? -8.871  -40.922 6.74    1   36.48  ? 193 PHE A CZ  1 
ATOM   3709 N N   . ALA B 2 198 ? -4.095  -37.682 7.571   1   35.63  ? 194 ALA A N   1 
ATOM   3710 C CA  . ALA B 2 198 ? -2.897  -38.529 7.583   1   37.53  ? 194 ALA A CA  1 
ATOM   3711 C C   . ALA B 2 198 ? -2.181  -38.48  8.938   1   36.66  ? 194 ALA A C   1 
ATOM   3712 O O   . ALA B 2 198 ? -1.848  -39.535 9.517   1   37.76  ? 194 ALA A O   1 
ATOM   3713 C CB  . ALA B 2 198 ? -1.97   -38.127 6.451   1   35.68  ? 194 ALA A CB  1 
ATOM   3714 N N   . GLU B 2 199 ? -1.996  -37.25  9.449   1   34.85  ? 195 GLU A N   1 
ATOM   3715 C CA  . GLU B 2 199 ? -1.234  -36.989 10.67   1   37.61  ? 195 GLU A CA  1 
ATOM   3716 C C   . GLU B 2 199 ? -1.9    -37.617 11.894  1   40.83  ? 195 GLU A C   1 
ATOM   3717 O O   . GLU B 2 199 ? -1.243  -38.136 12.786  1   45.84  ? 195 GLU A O   1 
ATOM   3718 C CB  . GLU B 2 199 ? -1.029  -35.481 10.847  1   36.42  ? 195 GLU A CB  1 
ATOM   3719 C CG  . GLU B 2 199 ? -0.153  -35.093 12.044  1   36.64  ? 195 GLU A CG  1 
ATOM   3720 C CD  . GLU B 2 199 ? 0.342   -33.66  12.001  1   36.08  ? 195 GLU A CD  1 
ATOM   3721 O OE1 . GLU B 2 199 ? 0.176   -33.048 10.911  1   35.49  ? 195 GLU A OE1 1 
ATOM   3722 O OE2 . GLU B 2 199 ? 0.854   -33.14  13.025  1   37.44  ? 195 GLU A OE2 1 
ATOM   3723 N N   . MET B 2 200 ? -3.221  -37.561 11.955  1   41.85  ? 196 MET A N   1 
ATOM   3724 C CA  . MET B 2 200 ? -3.921  -38.243 13.033  1   40.36  ? 196 MET A CA  1 
ATOM   3725 C C   . MET B 2 200 ? -3.682  -39.755 13.008  1   37.86  ? 196 MET A C   1 
ATOM   3726 O O   . MET B 2 200 ? -3.728  -40.384 14.048  1   37.98  ? 196 MET A O   1 
ATOM   3727 C CB  . MET B 2 200 ? -5.43   -37.97  12.952  1   39.24  ? 196 MET A CB  1 
ATOM   3728 C CG  . MET B 2 200 ? -5.84   -36.663 13.551  1   39.38  ? 196 MET A CG  1 
ATOM   3729 S SD  . MET B 2 200 ? -7.637  -36.532 13.681  1   39.74  ? 196 MET A SD  1 
ATOM   3730 C CE  . MET B 2 200 ? -8.102  -36.479 11.951  1   38.32  ? 196 MET A CE  1 
ATOM   3731 N N   . VAL B 2 201 ? -3.479  -40.346 11.831  1   37.22  ? 197 VAL A N   1 
ATOM   3732 C CA  . VAL B 2 201 ? -3.264  -41.78  11.736  1   40.91  ? 197 VAL A CA  1 
ATOM   3733 C C   . VAL B 2 201 ? -1.814  -42.096 12.133  1   42.98  ? 197 VAL A C   1 
ATOM   3734 O O   . VAL B 2 201 ? -1.578  -43.009 12.917  1   43.64  ? 197 VAL A O   1 
ATOM   3735 C CB  . VAL B 2 201 ? -3.597  -42.343 10.329  1   42.2   ? 197 VAL A CB  1 
ATOM   3736 C CG1 . VAL B 2 201 ? -3.125  -43.78  10.178  1   42.87  ? 197 VAL A CG1 1 
ATOM   3737 C CG2 . VAL B 2 201 ? -5.072  -42.269 9.968   1   40.44  ? 197 VAL A CG2 1 
ATOM   3738 N N   . THR B 2 202 ? -0.841  -41.324 11.614  1   45.84  ? 198 THR A N   1 
ATOM   3739 C CA  . THR B 2 202 ? 0.591   -41.629 11.803  1   45.5   ? 198 THR A CA  1 
ATOM   3740 C C   . THR B 2 202 ? 1.146   -40.941 13.048  1   46.37  ? 198 THR A C   1 
ATOM   3741 O O   . THR B 2 202 ? 2.125   -41.416 13.583  1   50.21  ? 198 THR A O   1 
ATOM   3742 C CB  . THR B 2 202 ? 1.404   -41.171 10.598  1   43.9   ? 198 THR A CB  1 
ATOM   3743 O OG1 . THR B 2 202 ? 1.162   -39.758 10.499  1   47.39  ? 198 THR A OG1 1 
ATOM   3744 C CG2 . THR B 2 202 ? 0.958   -41.812 9.299   1   42.05  ? 198 THR A CG2 1 
ATOM   3745 N N   . ARG B 2 203 ? 0.572   -39.791 13.458  1   47.62  ? 199 ARG A N   1 
ATOM   3746 C CA  . ARG B 2 203 ? 1.091   -38.953 14.533  1   49.63  ? 199 ARG A CA  1 
ATOM   3747 C C   . ARG B 2 203 ? 2.362   -38.209 14.107  1   49.93  ? 199 ARG A C   1 
ATOM   3748 O O   . ARG B 2 203 ? 3.056   -37.667 14.96   1   49.66  ? 199 ARG A O   1 
ATOM   3749 C CB  . ARG B 2 203 ? 1.399   -39.734 15.817  1   54.27  ? 199 ARG A CB  1 
ATOM   3750 C CG  . ARG B 2 203 ? 0.345   -39.685 16.914  1   58.87  ? 199 ARG A CG  1 
ATOM   3751 C CD  . ARG B 2 203 ? 0.338   -40.95  17.752  1   58.73  ? 199 ARG A CD  1 
ATOM   3752 N NE  . ARG B 2 203 ? 0.005   -42.04  16.829  1   60.71  ? 199 ARG A NE  1 
ATOM   3753 C CZ  . ARG B 2 203 ? 0.725   -43.145 16.635  1   63.37  ? 199 ARG A CZ  1 
ATOM   3754 N NH1 . ARG B 2 203 ? 1.705   -43.473 17.48   1   61.59  ? 199 ARG A NH1 1 
ATOM   3755 N NH2 . ARG B 2 203 ? 0.411   -43.936 15.615  1   60.82  ? 199 ARG A NH2 1 
ATOM   3756 N N   . ARG B 2 204 ? 2.644   -38.157 12.802  1   47.47  ? 200 ARG A N   1 
ATOM   3757 C CA  . ARG B 2 204 ? 3.689   -37.292 12.255  1   52     ? 200 ARG A CA  1 
ATOM   3758 C C   . ARG B 2 204 ? 3.151   -36.523 11.039  1   50.38  ? 200 ARG A C   1 
ATOM   3759 O O   . ARG B 2 204 ? 2.167   -36.946 10.414  1   51.3   ? 200 ARG A O   1 
ATOM   3760 C CB  . ARG B 2 204 ? 4.928   -38.117 11.897  1   52.45  ? 200 ARG A CB  1 
ATOM   3761 C CG  . ARG B 2 204 ? 4.567   -39.183 10.875  1   57.39  ? 200 ARG A CG  1 
ATOM   3762 C CD  . ARG B 2 204 ? 5.712   -40.044 10.376  1   56.97  ? 200 ARG A CD  1 
ATOM   3763 N NE  . ARG B 2 204 ? 5.404   -40.643 9.073   1   59.64  ? 200 ARG A NE  1 
ATOM   3764 C CZ  . ARG B 2 204 ? 6.322   -41.252 8.312   1   63.9   ? 200 ARG A CZ  1 
ATOM   3765 N NH1 . ARG B 2 204 ? 7.571   -41.351 8.752   1   64.23  ? 200 ARG A NH1 1 
ATOM   3766 N NH2 . ARG B 2 204 ? 6.004   -41.75  7.12    1   57.78  ? 200 ARG A NH2 1 
ATOM   3767 N N   . ALA B 2 205 ? 3.784   -35.378 10.725  1   45.09  ? 201 ALA A N   1 
ATOM   3768 C CA  . ALA B 2 205 ? 3.278   -34.536 9.653   1   39.23  ? 201 ALA A CA  1 
ATOM   3769 C C   . ALA B 2 205 ? 3.518   -35.268 8.348   1   39.19  ? 201 ALA A C   1 
ATOM   3770 O O   . ALA B 2 205 ? 4.479   -36.012 8.231   1   41.78  ? 201 ALA A O   1 
ATOM   3771 C CB  . ALA B 2 205 ? 3.915   -33.188 9.649   1   37.22  ? 201 ALA A CB  1 
ATOM   3772 N N   . LEU B 2 206 ? 2.621   -35.1   7.396   1   36.6   ? 202 LEU A N   1 
ATOM   3773 C CA  . LEU B 2 206 ? 2.679   -35.868 6.168   1   38.78  ? 202 LEU A CA  1 
ATOM   3774 C C   . LEU B 2 206 ? 3.767   -35.293 5.258   1   38.12  ? 202 LEU A C   1 
ATOM   3775 O O   . LEU B 2 206 ? 4.49    -36.035 4.631   1   39.89  ? 202 LEU A O   1 
ATOM   3776 C CB  . LEU B 2 206 ? 1.308   -35.852 5.473   1   36.38  ? 202 LEU A CB  1 
ATOM   3777 C CG  . LEU B 2 206 ? 1.22    -36.69  4.184   1   37.5   ? 202 LEU A CG  1 
ATOM   3778 C CD1 . LEU B 2 206 ? 1.381   -38.206 4.412   1   35.04  ? 202 LEU A CD1 1 
ATOM   3779 C CD2 . LEU B 2 206 ? -0.088  -36.378 3.467   1   33.51  ? 202 LEU A CD2 1 
ATOM   3780 N N   . PHE B 2 207 ? 3.855   -33.963 5.172   1   38.46  ? 203 PHE A N   1 
ATOM   3781 C CA  . PHE B 2 207 ? 4.823   -33.29  4.319   1   37.33  ? 203 PHE A CA  1 
ATOM   3782 C C   . PHE B 2 207 ? 5.577   -32.245 5.134   1   38.62  ? 203 PHE A C   1 
ATOM   3783 O O   . PHE B 2 207 ? 5.205   -31.068 5.11    1   41.22  ? 203 PHE A O   1 
ATOM   3784 C CB  . PHE B 2 207 ? 4.046   -32.503 3.26    1   38.59  ? 203 PHE A CB  1 
ATOM   3785 C CG  . PHE B 2 207 ? 3.145   -33.355 2.381   1   37.01  ? 203 PHE A CG  1 
ATOM   3786 C CD1 . PHE B 2 207 ? 3.659   -34.44  1.669   1   37.19  ? 203 PHE A CD1 1 
ATOM   3787 C CD2 . PHE B 2 207 ? 1.797   -33.055 2.277   1   36.84  ? 203 PHE A CD2 1 
ATOM   3788 C CE1 . PHE B 2 207 ? 2.833   -35.189 0.864   1   37.06  ? 203 PHE A CE1 1 
ATOM   3789 C CE2 . PHE B 2 207 ? 0.97    -33.837 1.479   1   35.8   ? 203 PHE A CE2 1 
ATOM   3790 C CZ  . PHE B 2 207 ? 1.498   -34.889 0.766   1   34.08  ? 203 PHE A CZ  1 
ATOM   3791 N N   . PRO B 2 208 ? 6.61    -32.627 5.926   1   36.99  ? 204 PRO A N   1 
ATOM   3792 C CA  . PRO B 2 208 ? 7.3     -31.653 6.776   1   37.42  ? 204 PRO A CA  1 
ATOM   3793 C C   . PRO B 2 208 ? 8.416   -30.945 6.013   1   39.71  ? 204 PRO A C   1 
ATOM   3794 O O   . PRO B 2 208 ? 9.583   -31.225 6.25    1   39.84  ? 204 PRO A O   1 
ATOM   3795 C CB  . PRO B 2 208 ? 7.881   -32.561 7.895   1   37.32  ? 204 PRO A CB  1 
ATOM   3796 C CG  . PRO B 2 208 ? 8.163   -33.911 7.199   1   37.13  ? 204 PRO A CG  1 
ATOM   3797 C CD  . PRO B 2 208 ? 7.128   -34.007 6.068   1   36.04  ? 204 PRO A CD  1 
ATOM   3798 N N   . GLY B 2 209 ? 8.053   -30.044 5.103   1   40.29  ? 205 GLY A N   1 
ATOM   3799 C CA  . GLY B 2 209 ? 9.034   -29.31  4.324   1   43.52  ? 205 GLY A CA  1 
ATOM   3800 C C   . GLY B 2 209 ? 9.785   -28.283 5.17    1   49.04  ? 205 GLY A C   1 
ATOM   3801 O O   . GLY B 2 209 ? 9.238   -27.809 6.161   1   48.37  ? 205 GLY A O   1 
ATOM   3802 N N   . ASP B 2 210 ? 11.03   -27.952 4.782   1   49.92  ? 206 ASP A N   1 
ATOM   3803 C CA  . ASP B 2 210 ? 11.767  -26.894 5.465   1   56.01  ? 206 ASP A CA  1 
ATOM   3804 C C   . ASP B 2 210 ? 11.903  -25.644 4.599   1   54.18  ? 206 ASP A C   1 
ATOM   3805 O O   . ASP B 2 210 ? 12.645  -24.747 4.972   1   60.38  ? 206 ASP A O   1 
ATOM   3806 C CB  . ASP B 2 210 ? 13.038  -27.368 6.165   1   61.32  ? 206 ASP A CB  1 
ATOM   3807 C CG  . ASP B 2 210 ? 14.106  -27.989 5.274   1   75.06  ? 206 ASP A CG  1 
ATOM   3808 O OD1 . ASP B 2 210 ? 13.872  -28.149 4.061   1   72.58  ? 206 ASP A OD1 1 
ATOM   3809 O OD2 . ASP B 2 210 ? 15.185  -28.354 5.796   1   97.09  ? 206 ASP A OD2 1 
ATOM   3810 N N   . SER B 2 211 ? 11.14   -25.547 3.5     1   46.63  ? 207 SER A N   1 
ATOM   3811 C CA  . SER B 2 211 ? 11.146  -24.368 2.639   1   45.38  ? 207 SER A CA  1 
ATOM   3812 C C   . SER B 2 211 ? 10.045  -24.517 1.597   1   43.79  ? 207 SER A C   1 
ATOM   3813 O O   . SER B 2 211 ? 9.528   -25.622 1.392   1   45.47  ? 207 SER A O   1 
ATOM   3814 C CB  . SER B 2 211 ? 12.524  -24.157 1.959   1   47.76  ? 207 SER A CB  1 
ATOM   3815 O OG  . SER B 2 211 ? 12.853  -25.3   1.191   1   46.59  ? 207 SER A OG  1 
ATOM   3816 N N   . GLU B 2 212 ? 9.655   -23.424 0.924   1   43.7   ? 208 GLU A N   1 
ATOM   3817 C CA  . GLU B 2 212 ? 8.62    -23.586 -0.104  1   43.71  ? 208 GLU A CA  1 
ATOM   3818 C C   . GLU B 2 212 ? 9.006   -24.686 -1.109  1   41.62  ? 208 GLU A C   1 
ATOM   3819 O O   . GLU B 2 212 ? 8.19    -25.507 -1.466  1   39.04  ? 208 GLU A O   1 
ATOM   3820 C CB  . GLU B 2 212 ? 8.326   -22.271 -0.836  1   47.86  ? 208 GLU A CB  1 
ATOM   3821 C CG  . GLU B 2 212 ? 7.455   -21.283 -0.059  1   51.93  ? 208 GLU A CG  1 
ATOM   3822 C CD  . GLU B 2 212 ? 7.247   -19.965 -0.799  1   59.35  ? 208 GLU A CD  1 
ATOM   3823 O OE1 . GLU B 2 212 ? 6.218   -19.742 -1.466  1   58.17  ? 208 GLU A OE1 1 
ATOM   3824 O OE2 . GLU B 2 212 ? 8.162   -19.117 -0.713  1   67.24  ? 208 GLU A OE2 1 
ATOM   3825 N N   . ILE B 2 213 ? 10.276  -24.736 -1.572  1   43.47  ? 209 ILE A N   1 
ATOM   3826 C CA  . ILE B 2 213 ? 10.609  -25.65  -2.651  1   40.59  ? 209 ILE A CA  1 
ATOM   3827 C C   . ILE B 2 213 ? 10.742  -27.073 -2.118  1   39.93  ? 209 ILE A C   1 
ATOM   3828 O O   . ILE B 2 213 ? 10.283  -28.021 -2.734  1   41.14  ? 209 ILE A O   1 
ATOM   3829 C CB  . ILE B 2 213 ? 11.814  -25.172 -3.481  1   42.22  ? 209 ILE A CB  1 
ATOM   3830 C CG1 . ILE B 2 213 ? 11.853  -25.953 -4.758  1   41.87  ? 209 ILE A CG1 1 
ATOM   3831 C CG2 . ILE B 2 213 ? 13.116  -25.287 -2.697  1   43.66  ? 209 ILE A CG2 1 
ATOM   3832 C CD1 . ILE B 2 213 ? 10.658  -25.644 -5.67   1   39.82  ? 209 ILE A CD1 1 
ATOM   3833 N N   . ASP B 2 214 ? 11.283  -27.214 -0.914  1   41.73  ? 210 ASP A N   1 
ATOM   3834 C CA  . ASP B 2 214 ? 11.348  -28.508 -0.287  1   41.72  ? 210 ASP A CA  1 
ATOM   3835 C C   . ASP B 2 214 ? 9.949   -29.02  -0.018  1   41.15  ? 210 ASP A C   1 
ATOM   3836 O O   . ASP B 2 214 ? 9.737   -30.219 -0.117  1   40.78  ? 210 ASP A O   1 
ATOM   3837 C CB  . ASP B 2 214 ? 12.115  -28.463 1.015   1   49.36  ? 210 ASP A CB  1 
ATOM   3838 C CG  . ASP B 2 214 ? 12.416  -29.834 1.598   1   57.18  ? 210 ASP A CG  1 
ATOM   3839 O OD1 . ASP B 2 214 ? 12.861  -30.744 0.817   1   60.4   ? 210 ASP A OD1 1 
ATOM   3840 O OD2 . ASP B 2 214 ? 12.214  -29.966 2.817   1   61.24  ? 210 ASP A OD2 1 
ATOM   3841 N N   . GLN B 2 215 ? 9.031   -28.131 0.364   1   38.53  ? 211 GLN A N   1 
ATOM   3842 C CA  . GLN B 2 215 ? 7.638   -28.558 0.653   1   39.13  ? 211 GLN A CA  1 
ATOM   3843 C C   . GLN B 2 215 ? 7.045   -29.16  -0.63   1   35.77  ? 211 GLN A C   1 
ATOM   3844 O O   . GLN B 2 215 ? 6.465   -30.266 -0.556  1   34.77  ? 211 GLN A O   1 
ATOM   3845 C CB  . GLN B 2 215 ? 6.797   -27.388 1.164   1   38.94  ? 211 GLN A CB  1 
ATOM   3846 C CG  . GLN B 2 215 ? 5.35    -27.755 1.474   1   36.37  ? 211 GLN A CG  1 
ATOM   3847 C CD  . GLN B 2 215 ? 5.173   -28.455 2.803   1   38.85  ? 211 GLN A CD  1 
ATOM   3848 O OE1 . GLN B 2 215 ? 5.984   -28.312 3.724   1   43.75  ? 211 GLN A OE1 1 
ATOM   3849 N NE2 . GLN B 2 215 ? 4.091   -29.209 2.919   1   38.05  ? 211 GLN A NE2 1 
ATOM   3850 N N   . LEU B 2 216 ? 7.208   -28.465 -1.758  1   35.52  ? 212 LEU A N   1 
ATOM   3851 C CA  . LEU B 2 216 ? 6.659   -28.95  -3.051  1   35.92  ? 212 LEU A CA  1 
ATOM   3852 C C   . LEU B 2 216 ? 7.251   -30.324 -3.389  1   36.48  ? 212 LEU A C   1 
ATOM   3853 O O   . LEU B 2 216 ? 6.472   -31.233 -3.735  1   37.02  ? 212 LEU A O   1 
ATOM   3854 C CB  . LEU B 2 216 ? 7       -27.932 -4.136  1   36.94  ? 212 LEU A CB  1 
ATOM   3855 C CG  . LEU B 2 216 ? 5.955   -26.84  -4.381  1   40.52  ? 212 LEU A CG  1 
ATOM   3856 C CD1 . LEU B 2 216 ? 6.545   -25.7   -5.191  1   41.42  ? 212 LEU A CD1 1 
ATOM   3857 C CD2 . LEU B 2 216 ? 4.732   -27.418 -5.072  1   36.25  ? 212 LEU A CD2 1 
ATOM   3858 N N   . PHE B 2 217 ? 8.575   -30.465 -3.296  1   35.63  ? 213 PHE A N   1 
ATOM   3859 C CA  . PHE B 2 217 ? 9.231   -31.738 -3.705  1   35.84  ? 213 PHE A CA  1 
ATOM   3860 C C   . PHE B 2 217 ? 8.75    -32.882 -2.82   1   36.8   ? 213 PHE A C   1 
ATOM   3861 O O   . PHE B 2 217 ? 8.583   -34.002 -3.338  1   40.91  ? 213 PHE A O   1 
ATOM   3862 C CB  . PHE B 2 217 ? 10.745  -31.505 -3.718  1   35.83  ? 213 PHE A CB  1 
ATOM   3863 C CG  . PHE B 2 217 ? 11.171  -30.625 -4.885  1   36.69  ? 213 PHE A CG  1 
ATOM   3864 C CD1 . PHE B 2 217 ? 10.295  -30.366 -5.934  1   36.24  ? 213 PHE A CD1 1 
ATOM   3865 C CD2 . PHE B 2 217 ? 12.437  -30.056 -4.931  1   38.87  ? 213 PHE A CD2 1 
ATOM   3866 C CE1 . PHE B 2 217 ? 10.674  -29.562 -6.996  1   37.03  ? 213 PHE A CE1 1 
ATOM   3867 C CE2 . PHE B 2 217 ? 12.813  -29.256 -5.998  1   39.4   ? 213 PHE A CE2 1 
ATOM   3868 C CZ  . PHE B 2 217 ? 11.932  -29.01  -7.026  1   38.4   ? 213 PHE A CZ  1 
ATOM   3869 N N   . ARG B 2 218 ? 8.522   -32.614 -1.534  1   37.12  ? 214 ARG A N   1 
ATOM   3870 C CA  . ARG B 2 218 ? 7.962   -33.669 -0.651  1   40.36  ? 214 ARG A CA  1 
ATOM   3871 C C   . ARG B 2 218 ? 6.597   -34.087 -1.213  1   39.48  ? 214 ARG A C   1 
ATOM   3872 O O   . ARG B 2 218 ? 6.392   -35.301 -1.434  1   38.93  ? 214 ARG A O   1 
ATOM   3873 C CB  . ARG B 2 218 ? 7.862   -33.154 0.787   1   42.23  ? 214 ARG A CB  1 
ATOM   3874 C CG  . ARG B 2 218 ? 9.243   -33.116 1.422   1   45.73  ? 214 ARG A CG  1 
ATOM   3875 C CD  . ARG B 2 218 ? 9.216   -32.471 2.79    1   47.76  ? 214 ARG A CD  1 
ATOM   3876 N NE  . ARG B 2 218 ? 10.569  -32.129 3.238   1   47.05  ? 214 ARG A NE  1 
ATOM   3877 C CZ  . ARG B 2 218 ? 11.248  -32.798 4.158   1   45.91  ? 214 ARG A CZ  1 
ATOM   3878 N NH1 . ARG B 2 218 ? 10.86   -34.009 4.516   1   46.88  ? 214 ARG A NH1 1 
ATOM   3879 N NH2 . ARG B 2 218 ? 12.305  -32.246 4.725   1   43.96  ? 214 ARG A NH2 1 
ATOM   3880 N N   . ILE B 2 219 ? 5.711   -33.116 -1.442  1   37.39  ? 215 ILE A N   1 
ATOM   3881 C CA  . ILE B 2 219 ? 4.384   -33.425 -2.05   1   37.46  ? 215 ILE A CA  1 
ATOM   3882 C C   . ILE B 2 219 ? 4.625   -34.194 -3.358  1   37.67  ? 215 ILE A C   1 
ATOM   3883 O O   . ILE B 2 219 ? 4.004   -35.264 -3.541  1   36.77  ? 215 ILE A O   1 
ATOM   3884 C CB  . ILE B 2 219 ? 3.581   -32.132 -2.277  1   36.75  ? 215 ILE A CB  1 
ATOM   3885 C CG1 . ILE B 2 219 ? 3.238   -31.452 -0.953  1   35.9   ? 215 ILE A CG1 1 
ATOM   3886 C CG2 . ILE B 2 219 ? 2.331   -32.397 -3.116  1   34.71  ? 215 ILE A CG2 1 
ATOM   3887 C CD1 . ILE B 2 219 ? 2.811   -30.003 -1.096  1   37.36  ? 215 ILE A CD1 1 
ATOM   3888 N N   . PHE B 2 220 ? 5.506   -33.677 -4.222  1   36.53  ? 216 PHE A N   1 
ATOM   3889 C CA  . PHE B 2 220 ? 5.745   -34.339 -5.498  1   37.15  ? 216 PHE A CA  1 
ATOM   3890 C C   . PHE B 2 220 ? 6.268   -35.761 -5.291  1   38.81  ? 216 PHE A C   1 
ATOM   3891 O O   . PHE B 2 220 ? 5.864   -36.664 -6.02   1   39.4   ? 216 PHE A O   1 
ATOM   3892 C CB  . PHE B 2 220 ? 6.72    -33.598 -6.41   1   35.39  ? 216 PHE A CB  1 
ATOM   3893 C CG  . PHE B 2 220 ? 6.214   -32.269 -6.945  1   34.83  ? 216 PHE A CG  1 
ATOM   3894 C CD1 . PHE B 2 220 ? 4.929   -31.835 -6.668  1   32.57  ? 216 PHE A CD1 1 
ATOM   3895 C CD2 . PHE B 2 220 ? 7.029   -31.483 -7.754  1   36.18  ? 216 PHE A CD2 1 
ATOM   3896 C CE1 . PHE B 2 220 ? 4.489   -30.63  -7.163  1   33.05  ? 216 PHE A CE1 1 
ATOM   3897 C CE2 . PHE B 2 220 ? 6.567   -30.279 -8.262  1   35.44  ? 216 PHE A CE2 1 
ATOM   3898 C CZ  . PHE B 2 220 ? 5.312   -29.854 -7.953  1   34.5   ? 216 PHE A CZ  1 
ATOM   3899 N N   . ARG B 2 221 ? 7.145   -35.971 -4.305  1   37.67  ? 217 ARG A N   1 
ATOM   3900 C CA  . ARG B 2 221 ? 7.75    -37.288 -4.148  1   40.31  ? 217 ARG A CA  1 
ATOM   3901 C C   . ARG B 2 221 ? 6.739   -38.279 -3.584  1   40.35  ? 217 ARG A C   1 
ATOM   3902 O O   . ARG B 2 221 ? 6.957   -39.472 -3.67   1   44.56  ? 217 ARG A O   1 
ATOM   3903 C CB  . ARG B 2 221 ? 9.038   -37.316 -3.301  1   39.12  ? 217 ARG A CB  1 
ATOM   3904 C CG  . ARG B 2 221 ? 10.261  -36.863 -4.076  1   41.15  ? 217 ARG A CG  1 
ATOM   3905 C CD  . ARG B 2 221 ? 11.615  -37.066 -3.346  1   44.47  ? 217 ARG A CD  1 
ATOM   3906 N NE  . ARG B 2 221 ? 11.514  -36.342 -2.077  1   47.3   ? 217 ARG A NE  1 
ATOM   3907 C CZ  . ARG B 2 221 ? 12.038  -35.141 -1.85   1   46.31  ? 217 ARG A CZ  1 
ATOM   3908 N NH1 . ARG B 2 221 ? 11.907  -34.629 -0.641  1   45.75  ? 217 ARG A NH1 1 
ATOM   3909 N NH2 . ARG B 2 221 ? 12.695  -34.499 -2.809  1   43.73  ? 217 ARG A NH2 1 
ATOM   3910 N N   . THR B 2 222 ? 5.64    -37.799 -3.008  1   40.71  ? 218 THR A N   1 
ATOM   3911 C CA  . THR B 2 222 ? 4.656   -38.661 -2.376  1   40.58  ? 218 THR A CA  1 
ATOM   3912 C C   . THR B 2 222 ? 3.5     -38.937 -3.341  1   42.62  ? 218 THR A C   1 
ATOM   3913 O O   . THR B 2 222 ? 3.045   -40.058 -3.397  1   46.82  ? 218 THR A O   1 
ATOM   3914 C CB  . THR B 2 222 ? 4.151   -38.002 -1.088  1   42.83  ? 218 THR A CB  1 
ATOM   3915 O OG1 . THR B 2 222 ? 5.287   -37.965 -0.224  1   45.16  ? 218 THR A OG1 1 
ATOM   3916 C CG2 . THR B 2 222 ? 2.962   -38.727 -0.46   1   40.76  ? 218 THR A CG2 1 
ATOM   3917 N N   . LEU B 2 223 ? 2.997   -37.923 -4.055  1   40.24  ? 219 LEU A N   1 
ATOM   3918 C CA  . LEU B 2 223 ? 1.853   -38.043 -4.931  1   37.86  ? 219 LEU A CA  1 
ATOM   3919 C C   . LEU B 2 223 ? 2.246   -38.022 -6.401  1   39.29  ? 219 LEU A C   1 
ATOM   3920 O O   . LEU B 2 223 ? 1.36    -38.015 -7.255  1   41.7   ? 219 LEU A O   1 
ATOM   3921 C CB  . LEU B 2 223 ? 0.967   -36.823 -4.673  1   38.13  ? 219 LEU A CB  1 
ATOM   3922 C CG  . LEU B 2 223 ? 0.509   -36.641 -3.226  1   38.12  ? 219 LEU A CG  1 
ATOM   3923 C CD1 . LEU B 2 223 ? -0.407  -35.462 -3.11   1   33.69  ? 219 LEU A CD1 1 
ATOM   3924 C CD2 . LEU B 2 223 ? -0.158  -37.897 -2.698  1   39.38  ? 219 LEU A CD2 1 
ATOM   3925 N N   . GLY B 2 224 ? 3.546   -37.968 -6.714  1   41.61  ? 220 GLY A N   1 
ATOM   3926 C CA  . GLY B 2 224 ? 4.01    -37.892 -8.086  1   37.39  ? 220 GLY A CA  1 
ATOM   3927 C C   . GLY B 2 224 ? 4.044   -36.434 -8.512  1   37.24  ? 220 GLY A C   1 
ATOM   3928 O O   . GLY B 2 224 ? 3.308   -35.625 -7.962  1   36.21  ? 220 GLY A O   1 
ATOM   3929 N N   . THR B 2 225 ? 4.941   -36.095 -9.455  1   38.45  ? 221 THR A N   1 
ATOM   3930 C CA  . THR B 2 225 ? 5.042   -34.718 -9.9    1   39.12  ? 221 THR A CA  1 
ATOM   3931 C C   . THR B 2 225 ? 3.839   -34.51  -10.812 1   42.31  ? 221 THR A C   1 
ATOM   3932 O O   . THR B 2 225 ? 3.609   -35.297 -11.714 1   46.68  ? 221 THR A O   1 
ATOM   3933 C CB  . THR B 2 225 ? 6.351   -34.462 -10.659 1   39.51  ? 221 THR A CB  1 
ATOM   3934 O OG1 . THR B 2 225 ? 7.514   -34.702 -9.857  1   41.81  ? 221 THR A OG1 1 
ATOM   3935 C CG2 . THR B 2 225 ? 6.424   -33.042 -11.187 1   37.33  ? 221 THR A CG2 1 
ATOM   3936 N N   . PRO B 2 226 ? 3.038   -33.447 -10.665 1   42.48  ? 222 PRO A N   1 
ATOM   3937 C CA  . PRO B 2 226 ? 1.838   -33.307 -11.497 1   44.52  ? 222 PRO A CA  1 
ATOM   3938 C C   . PRO B 2 226 ? 2.17    -32.811 -12.898 1   46.93  ? 222 PRO A C   1 
ATOM   3939 O O   . PRO B 2 226 ? 3.125   -32.069 -13.069 1   52     ? 222 PRO A O   1 
ATOM   3940 C CB  . PRO B 2 226 ? 1.03    -32.286 -10.721 1   41.86  ? 222 PRO A CB  1 
ATOM   3941 C CG  . PRO B 2 226 ? 2.099   -31.418 -10.056 1   41.15  ? 222 PRO A CG  1 
ATOM   3942 C CD  . PRO B 2 226 ? 3.218   -32.377 -9.675  1   42.17  ? 222 PRO A CD  1 
ATOM   3943 N N   . ASP B 2 227 ? 1.387   -33.257 -13.889 1   49.92  ? 223 ASP A N   1 
ATOM   3944 C CA  . ASP B 2 227 ? 1.49    -32.847 -15.291 1   50.55  ? 223 ASP A CA  1 
ATOM   3945 C C   . ASP B 2 227 ? 0.122   -32.323 -15.754 1   48.29  ? 223 ASP A C   1 
ATOM   3946 O O   . ASP B 2 227 ? -0.819  -32.182 -14.952 1   43.78  ? 223 ASP A O   1 
ATOM   3947 C CB  . ASP B 2 227 ? 1.997   -33.991 -16.161 1   51.79  ? 223 ASP A CB  1 
ATOM   3948 C CG  . ASP B 2 227 ? 1.082   -35.204 -16.147 1   57.14  ? 223 ASP A CG  1 
ATOM   3949 O OD1 . ASP B 2 227 ? -0.059  -35.075 -15.684 1   54.63  ? 223 ASP A OD1 1 
ATOM   3950 O OD2 . ASP B 2 227 ? 1.522   -36.276 -16.57  1   66.5   ? 223 ASP A OD2 1 
ATOM   3951 N N   . GLU B 2 228 ? 0.013   -32.03  -17.054 1   48.54  ? 224 GLU A N   1 
ATOM   3952 C CA  . GLU B 2 228 ? -1.208  -31.475 -17.627 1   50.41  ? 224 GLU A CA  1 
ATOM   3953 C C   . GLU B 2 228 ? -2.397  -32.436 -17.514 1   49.34  ? 224 GLU A C   1 
ATOM   3954 O O   . GLU B 2 228 ? -3.538  -31.99  -17.421 1   48.22  ? 224 GLU A O   1 
ATOM   3955 C CB  . GLU B 2 228 ? -0.945  -31.009 -19.061 1   51.09  ? 224 GLU A CB  1 
ATOM   3956 C CG  . GLU B 2 228 ? -0.245  -29.657 -19.099 1   52.77  ? 224 GLU A CG  1 
ATOM   3957 C CD  . GLU B 2 228 ? -1.028  -28.462 -18.549 1   59.04  ? 224 GLU A CD  1 
ATOM   3958 O OE1 . GLU B 2 228 ? -2.303  -28.437 -18.464 1   54.79  ? 224 GLU A OE1 1 
ATOM   3959 O OE2 . GLU B 2 228 ? -0.293  -27.528 -18.137 1   59.67  ? 224 GLU A OE2 1 
ATOM   3960 N N   . VAL B 2 229 ? -2.108  -33.744 -17.513 1   50.56  ? 225 VAL A N   1 
ATOM   3961 C CA  . VAL B 2 229 ? -3.104  -34.795 -17.426 1   50.97  ? 225 VAL A CA  1 
ATOM   3962 C C   . VAL B 2 229 ? -3.727  -34.839 -16.034 1   51.16  ? 225 VAL A C   1 
ATOM   3963 O O   . VAL B 2 229 ? -4.936  -34.804 -15.9   1   53.89  ? 225 VAL A O   1 
ATOM   3964 C CB  . VAL B 2 229 ? -2.485  -36.156 -17.792 1   54.85  ? 225 VAL A CB  1 
ATOM   3965 C CG1 . VAL B 2 229 ? -3.479  -37.294 -17.539 1   56.04  ? 225 VAL A CG1 1 
ATOM   3966 C CG2 . VAL B 2 229 ? -1.964  -36.166 -19.238 1   54.87  ? 225 VAL A CG2 1 
ATOM   3967 N N   . VAL B 2 230 ? -2.932  -34.967 -14.976 1   48.71  ? 226 VAL A N   1 
ATOM   3968 C CA  . VAL B 2 230 ? -3.541  -35.022 -13.66  1   47.67  ? 226 VAL A CA  1 
ATOM   3969 C C   . VAL B 2 230 ? -4.027  -33.623 -13.273 1   45.81  ? 226 VAL A C   1 
ATOM   3970 O O   . VAL B 2 230 ? -4.941  -33.48  -12.458 1   43.87  ? 226 VAL A O   1 
ATOM   3971 C CB  . VAL B 2 230 ? -2.504  -35.601 -12.672 1   51.87  ? 226 VAL A CB  1 
ATOM   3972 C CG1 . VAL B 2 230 ? -1.339  -34.667 -12.509 1   57.77  ? 226 VAL A CG1 1 
ATOM   3973 C CG2 . VAL B 2 230 ? -3.067  -35.861 -11.287 1   56.08  ? 226 VAL A CG2 1 
ATOM   3974 N N   . TRP B 2 231 ? -3.405  -32.569 -13.818 1   45.17  ? 227 TRP A N   1 
ATOM   3975 C CA  . TRP B 2 231 ? -3.72   -31.223 -13.352 1   46.32  ? 227 TRP A CA  1 
ATOM   3976 C C   . TRP B 2 231 ? -3.623  -30.212 -14.489 1   48.21  ? 227 TRP A C   1 
ATOM   3977 O O   . TRP B 2 231 ? -2.594  -29.555 -14.632 1   45.88  ? 227 TRP A O   1 
ATOM   3978 C CB  . TRP B 2 231 ? -2.823  -30.819 -12.17  1   43.86  ? 227 TRP A CB  1 
ATOM   3979 C CG  . TRP B 2 231 ? -3.145  -29.489 -11.534 1   42.89  ? 227 TRP A CG  1 
ATOM   3980 C CD1 . TRP B 2 231 ? -4.184  -28.657 -11.824 1   41.79  ? 227 TRP A CD1 1 
ATOM   3981 C CD2 . TRP B 2 231 ? -2.412  -28.848 -10.459 1   42.63  ? 227 TRP A CD2 1 
ATOM   3982 N NE1 . TRP B 2 231 ? -4.151  -27.548 -11.02  1   42.09  ? 227 TRP A NE1 1 
ATOM   3983 C CE2 . TRP B 2 231 ? -3.088  -27.64  -10.167 1   40.98  ? 227 TRP A CE2 1 
ATOM   3984 C CE3 . TRP B 2 231 ? -1.272  -29.191 -9.713  1   41.7   ? 227 TRP A CE3 1 
ATOM   3985 C CZ2 . TRP B 2 231 ? -2.661  -26.769 -9.173  1   41.8   ? 227 TRP A CZ2 1 
ATOM   3986 C CZ3 . TRP B 2 231 ? -0.846  -28.335 -8.719  1   41.96  ? 227 TRP A CZ3 1 
ATOM   3987 C CH2 . TRP B 2 231 ? -1.531  -27.141 -8.459  1   43.88  ? 227 TRP A CH2 1 
ATOM   3988 N N   . PRO B 2 232 ? -4.703  -30.014 -15.289 1   51.39  ? 228 PRO A N   1 
ATOM   3989 C CA  . PRO B 2 232 ? -4.668  -29.072 -16.417 1   53.03  ? 228 PRO A CA  1 
ATOM   3990 C C   . PRO B 2 232 ? -4.421  -27.663 -15.863 1   52.71  ? 228 PRO A C   1 
ATOM   3991 O O   . PRO B 2 232 ? -5.031  -27.28  -14.853 1   46.78  ? 228 PRO A O   1 
ATOM   3992 C CB  . PRO B 2 232 ? -6.053  -29.191 -17.137 1   50.96  ? 228 PRO A CB  1 
ATOM   3993 C CG  . PRO B 2 232 ? -6.8    -30.272 -16.374 1   47.94  ? 228 PRO A CG  1 
ATOM   3994 C CD  . PRO B 2 232 ? -6.035  -30.623 -15.107 1   50.55  ? 228 PRO A CD  1 
ATOM   3995 N N   . GLY B 2 233 ? -3.5    -26.912 -16.505 1   53.79  ? 229 GLY A N   1 
ATOM   3996 C CA  . GLY B 2 233 ? -3.106  -25.617 -15.957 1   55.01  ? 229 GLY A CA  1 
ATOM   3997 C C   . GLY B 2 233 ? -1.753  -25.588 -15.219 1   57.19  ? 229 GLY A C   1 
ATOM   3998 O O   . GLY B 2 233 ? -1.119  -24.537 -15.199 1   61.14  ? 229 GLY A O   1 
ATOM   3999 N N   . VAL B 2 234 ? -1.313  -26.709 -14.61  1   51.54  ? 230 VAL A N   1 
ATOM   4000 C CA  . VAL B 2 234 ? -0.194  -26.724 -13.671 1   47.06  ? 230 VAL A CA  1 
ATOM   4001 C C   . VAL B 2 234 ? 1.058   -26.105 -14.325 1   48.64  ? 230 VAL A C   1 
ATOM   4002 O O   . VAL B 2 234 ? 1.779   -25.325 -13.705 1   46.27  ? 230 VAL A O   1 
ATOM   4003 C CB  . VAL B 2 234 ? 0.11    -28.126 -13.102 1   41.68  ? 230 VAL A CB  1 
ATOM   4004 C CG1 . VAL B 2 234 ? 0.635   -29.092 -14.151 1   37.64  ? 230 VAL A CG1 1 
ATOM   4005 C CG2 . VAL B 2 234 ? 1.142   -28.088 -11.979 1   40.72  ? 230 VAL A CG2 1 
ATOM   4006 N N   . THR B 2 235 ? 1.33    -26.441 -15.588 1   50.66  ? 231 THR A N   1 
ATOM   4007 C CA  . THR B 2 235 ? 2.565   -26.008 -16.223 1   50.73  ? 231 THR A CA  1 
ATOM   4008 C C   . THR B 2 235 ? 2.471   -24.533 -16.599 1   54.09  ? 231 THR A C   1 
ATOM   4009 O O   . THR B 2 235 ? 3.44    -23.992 -17.111 1   61.64  ? 231 THR A O   1 
ATOM   4010 C CB  . THR B 2 235 ? 2.944   -26.853 -17.437 1   49.94  ? 231 THR A CB  1 
ATOM   4011 O OG1 . THR B 2 235 ? 1.874   -26.648 -18.345 1   58.87  ? 231 THR A OG1 1 
ATOM   4012 C CG2 . THR B 2 235 ? 3.087   -28.332 -17.146 1   48.21  ? 231 THR A CG2 1 
ATOM   4013 N N   . SER B 2 236 ? 1.332   -23.892 -16.337 1   54.74  ? 232 SER A N   1 
ATOM   4014 C CA  . SER B 2 236 ? 1.106   -22.508 -16.726 1   61.02  ? 232 SER A CA  1 
ATOM   4015 C C   . SER B 2 236 ? 1.158   -21.628 -15.489 1   62.83  ? 232 SER A C   1 
ATOM   4016 O O   . SER B 2 236 ? 1.002   -20.414 -15.57  1   71.01  ? 232 SER A O   1 
ATOM   4017 C CB  . SER B 2 236 ? -0.263  -22.318 -17.402 1   65.76  ? 232 SER A CB  1 
ATOM   4018 O OG  . SER B 2 236 ? -0.181  -22.48  -18.815 1   70.99  ? 232 SER A OG  1 
ATOM   4019 N N   . MET B 2 237 ? 1.304   -22.256 -14.327 1   58.23  ? 233 MET A N   1 
ATOM   4020 C CA  . MET B 2 237 ? 1.231   -21.513 -13.076 1   57.69  ? 233 MET A CA  1 
ATOM   4021 C C   . MET B 2 237 ? 2.49    -20.683 -12.854 1   52.41  ? 233 MET A C   1 
ATOM   4022 O O   . MET B 2 237 ? 3.575   -21.063 -13.289 1   50.22  ? 233 MET A O   1 
ATOM   4023 C CB  . MET B 2 237 ? 0.971   -22.462 -11.911 1   56.88  ? 233 MET A CB  1 
ATOM   4024 C CG  . MET B 2 237 ? -0.182  -23.314 -12.286 1   60.65  ? 233 MET A CG  1 
ATOM   4025 S SD  . MET B 2 237 ? -0.985  -23.913 -10.81  1   69.35  ? 233 MET A SD  1 
ATOM   4026 C CE  . MET B 2 237 ? -2.714  -23.729 -11.277 1   72.16  ? 233 MET A CE  1 
ATOM   4027 N N   . PRO B 2 238 ? 2.362   -19.526 -12.176 1   50     ? 234 PRO A N   1 
ATOM   4028 C CA  . PRO B 2 238 ? 3.457   -18.553 -12.152 1   50.45  ? 234 PRO A CA  1 
ATOM   4029 C C   . PRO B 2 238 ? 4.808   -19.051 -11.634 1   48.77  ? 234 PRO A C   1 
ATOM   4030 O O   . PRO B 2 238 ? 5.831   -18.605 -12.149 1   54.53  ? 234 PRO A O   1 
ATOM   4031 C CB  . PRO B 2 238 ? 2.876   -17.344 -11.356 1   49.85  ? 234 PRO A CB  1 
ATOM   4032 C CG  . PRO B 2 238 ? 1.362   -17.59  -11.349 1   48.52  ? 234 PRO A CG  1 
ATOM   4033 C CD  . PRO B 2 238 ? 1.19    -19.105 -11.381 1   45.88  ? 234 PRO A CD  1 
ATOM   4034 N N   . ASP B 2 239 ? 4.812   -19.989 -10.665 1   45.61  ? 235 ASP A N   1 
ATOM   4035 C CA  . ASP B 2 239 ? 6.054   -20.519 -10.114 1   47.87  ? 235 ASP A CA  1 
ATOM   4036 C C   . ASP B 2 239 ? 6.311   -21.962 -10.533 1   47.29  ? 235 ASP A C   1 
ATOM   4037 O O   . ASP B 2 239 ? 7.18    -22.603 -9.95   1   48.54  ? 235 ASP A O   1 
ATOM   4038 C CB  . ASP B 2 239 ? 6.19    -20.327 -8.609  1   46.15  ? 235 ASP A CB  1 
ATOM   4039 C CG  . ASP B 2 239 ? 6.039   -18.887 -8.171  1   47.2   ? 235 ASP A CG  1 
ATOM   4040 O OD1 . ASP B 2 239 ? 6.412   -18.006 -8.939  1   50.03  ? 235 ASP A OD1 1 
ATOM   4041 O OD2 . ASP B 2 239 ? 5.47    -18.648 -7.106  1   52.43  ? 235 ASP A OD2 1 
ATOM   4042 N N   . TYR B 2 240 ? 5.565   -22.462 -11.527 1   46.34  ? 236 TYR A N   1 
ATOM   4043 C CA  . TYR B 2 240 ? 5.864   -23.751 -12.142 1   45.56  ? 236 TYR A CA  1 
ATOM   4044 C C   . TYR B 2 240 ? 7.179   -23.628 -12.917 1   44.11  ? 236 TYR A C   1 
ATOM   4045 O O   . TYR B 2 240 ? 7.398   -22.633 -13.587 1   45.48  ? 236 TYR A O   1 
ATOM   4046 C CB  . TYR B 2 240 ? 4.71    -24.286 -13.018 1   45.9   ? 236 TYR A CB  1 
ATOM   4047 C CG  . TYR B 2 240 ? 5.084   -25.556 -13.767 1   46.18  ? 236 TYR A CG  1 
ATOM   4048 C CD1 . TYR B 2 240 ? 4.925   -26.809 -13.194 1   47.12  ? 236 TYR A CD1 1 
ATOM   4049 C CD2 . TYR B 2 240 ? 5.665   -25.501 -15.03  1   49.36  ? 236 TYR A CD2 1 
ATOM   4050 C CE1 . TYR B 2 240 ? 5.352   -27.964 -13.84  1   48.85  ? 236 TYR A CE1 1 
ATOM   4051 C CE2 . TYR B 2 240 ? 6.046   -26.65  -15.712 1   48.82  ? 236 TYR A CE2 1 
ATOM   4052 C CZ  . TYR B 2 240 ? 5.899   -27.882 -15.113 1   48.76  ? 236 TYR A CZ  1 
ATOM   4053 O OH  . TYR B 2 240 ? 6.305   -28.942 -15.884 1   51.83  ? 236 TYR A OH  1 
ATOM   4054 N N   . LYS B 2 241 ? 8.003   -24.671 -12.869 1   43.98  ? 237 LYS A N   1 
ATOM   4055 C CA  . LYS B 2 241 ? 9.251   -24.717 -13.61  1   45.63  ? 237 LYS A CA  1 
ATOM   4056 C C   . LYS B 2 241 ? 9.344   -26.068 -14.315 1   44.27  ? 237 LYS A C   1 
ATOM   4057 O O   . LYS B 2 241 ? 9.194   -27.106 -13.672 1   43.81  ? 237 LYS A O   1 
ATOM   4058 C CB  . LYS B 2 241 ? 10.448  -24.605 -12.652 1   47.67  ? 237 LYS A CB  1 
ATOM   4059 C CG  . LYS B 2 241 ? 10.578  -23.346 -11.809 1   51.96  ? 237 LYS A CG  1 
ATOM   4060 C CD  . LYS B 2 241 ? 10.793  -22.103 -12.667 1   60.01  ? 237 LYS A CD  1 
ATOM   4061 C CE  . LYS B 2 241 ? 11      -20.832 -11.838 1   72.6   ? 237 LYS A CE  1 
ATOM   4062 N NZ  . LYS B 2 241 ? 11.195  -19.569 -12.56  1   74.48  ? 237 LYS A NZ  1 
ATOM   4063 N N   . PRO B 2 242 ? 9.598   -26.081 -15.646 1   43.62  ? 238 PRO A N   1 
ATOM   4064 C CA  . PRO B 2 242 ? 9.856   -27.316 -16.392 1   44.13  ? 238 PRO A CA  1 
ATOM   4065 C C   . PRO B 2 242 ? 10.929  -28.244 -15.814 1   44.7   ? 238 PRO A C   1 
ATOM   4066 O O   . PRO B 2 242 ? 10.887  -29.459 -16.021 1   44.26  ? 238 PRO A O   1 
ATOM   4067 C CB  . PRO B 2 242 ? 10.321  -26.817 -17.786 1   46.01  ? 238 PRO A CB  1 
ATOM   4068 C CG  . PRO B 2 242 ? 10.114  -25.303 -17.829 1   45.67  ? 238 PRO A CG  1 
ATOM   4069 C CD  . PRO B 2 242 ? 9.695   -24.867 -16.465 1   43.91  ? 238 PRO A CD  1 
ATOM   4070 N N   . SER B 2 243 ? 11.925  -27.64  -15.147 1   44.77  ? 239 SER A N   1 
ATOM   4071 C CA  . SER B 2 243 ? 13.054  -28.329 -14.522 1   45.82  ? 239 SER A CA  1 
ATOM   4072 C C   . SER B 2 243 ? 12.65   -29.12  -13.28  1   42.84  ? 239 SER A C   1 
ATOM   4073 O O   . SER B 2 243 ? 13.436  -29.894 -12.781 1   42.57  ? 239 SER A O   1 
ATOM   4074 C CB  . SER B 2 243 ? 14.125  -27.336 -14.16  1   48.22  ? 239 SER A CB  1 
ATOM   4075 O OG  . SER B 2 243 ? 13.514  -26.335 -13.359 1   49.66  ? 239 SER A OG  1 
ATOM   4076 N N   . PHE B 2 244 ? 11.462  -28.874 -12.73  1   41.72  ? 240 PHE A N   1 
ATOM   4077 C CA  . PHE B 2 244 ? 10.974  -29.702 -11.641 1   41.68  ? 240 PHE A CA  1 
ATOM   4078 C C   . PHE B 2 244 ? 11.289  -31.169 -11.918 1   41.64  ? 240 PHE A C   1 
ATOM   4079 O O   . PHE B 2 244 ? 10.957  -31.709 -12.962 1   41.9   ? 240 PHE A O   1 
ATOM   4080 C CB  . PHE B 2 244 ? 9.453   -29.606 -11.48  1   40.02  ? 240 PHE A CB  1 
ATOM   4081 C CG  . PHE B 2 244 ? 8.999   -28.367 -10.723 1   43.39  ? 240 PHE A CG  1 
ATOM   4082 C CD1 . PHE B 2 244 ? 9.934   -27.53  -10.102 1   46.47  ? 240 PHE A CD1 1 
ATOM   4083 C CD2 . PHE B 2 244 ? 7.642   -28.044 -10.637 1   43.44  ? 240 PHE A CD2 1 
ATOM   4084 C CE1 . PHE B 2 244 ? 9.512   -26.402 -9.415  1   49.07  ? 240 PHE A CE1 1 
ATOM   4085 C CE2 . PHE B 2 244 ? 7.225   -26.904 -9.977  1   43.82  ? 240 PHE A CE2 1 
ATOM   4086 C CZ  . PHE B 2 244 ? 8.162   -26.1   -9.346  1   46.65  ? 240 PHE A CZ  1 
ATOM   4087 N N   . PRO B 2 245 ? 11.881  -31.898 -10.968 1   42.08  ? 241 PRO A N   1 
ATOM   4088 C CA  . PRO B 2 245 ? 12.079  -33.333 -11.167 1   44     ? 241 PRO A CA  1 
ATOM   4089 C C   . PRO B 2 245 ? 10.723  -34.023 -11.316 1   43.58  ? 241 PRO A C   1 
ATOM   4090 O O   . PRO B 2 245 ? 9.723   -33.595 -10.739 1   39.64  ? 241 PRO A O   1 
ATOM   4091 C CB  . PRO B 2 245 ? 12.883  -33.781 -9.915  1   43.57  ? 241 PRO A CB  1 
ATOM   4092 C CG  . PRO B 2 245 ? 13.474  -32.479 -9.381  1   43.73  ? 241 PRO A CG  1 
ATOM   4093 C CD  . PRO B 2 245 ? 12.455  -31.384 -9.722  1   42.11  ? 241 PRO A CD  1 
ATOM   4094 N N   . LYS B 2 246 ? 10.701  -35.053 -12.169 1   46.66  ? 242 LYS A N   1 
ATOM   4095 C CA  . LYS B 2 246 ? 9.474   -35.786 -12.447 1   47.25  ? 242 LYS A CA  1 
ATOM   4096 C C   . LYS B 2 246 ? 9.512   -37.038 -11.595 1   45.18  ? 242 LYS A C   1 
ATOM   4097 O O   . LYS B 2 246 ? 10.246  -37.925 -11.953 1   49.01  ? 242 LYS A O   1 
ATOM   4098 C CB  . LYS B 2 246 ? 9.381   -36.301 -13.894 1   47.95  ? 242 LYS A CB  1 
ATOM   4099 C CG  . LYS B 2 246 ? 9.331   -35.275 -15.013 1   53.13  ? 242 LYS A CG  1 
ATOM   4100 C CD  . LYS B 2 246 ? 8.465   -34.053 -14.69  1   56.88  ? 242 LYS A CD  1 
ATOM   4101 C CE  . LYS B 2 246 ? 8.729   -32.854 -15.598 1   59.28  ? 242 LYS A CE  1 
ATOM   4102 N NZ  . LYS B 2 246 ? 8.669   -33.291 -17.002 1   58.33  ? 242 LYS A NZ  1 
ATOM   4103 N N   . TRP B 2 247 ? 8.747   -37.095 -10.497 1   42.19  ? 243 TRP A N   1 
ATOM   4104 C CA  . TRP B 2 247 ? 8.72    -38.28  -9.651  1   40.67  ? 243 TRP A CA  1 
ATOM   4105 C C   . TRP B 2 247 ? 7.444   -39.067 -9.967  1   40.59  ? 243 TRP A C   1 
ATOM   4106 O O   . TRP B 2 247 ? 6.378   -38.491 -10.209 1   39.43  ? 243 TRP A O   1 
ATOM   4107 C CB  . TRP B 2 247 ? 8.753   -37.884 -8.158  1   39.45  ? 243 TRP A CB  1 
ATOM   4108 C CG  . TRP B 2 247 ? 10.098  -37.508 -7.591  1   39.28  ? 243 TRP A CG  1 
ATOM   4109 C CD1 . TRP B 2 247 ? 11.125  -38.355 -7.237  1   40.69  ? 243 TRP A CD1 1 
ATOM   4110 C CD2 . TRP B 2 247 ? 10.551  -36.175 -7.261  1   38.59  ? 243 TRP A CD2 1 
ATOM   4111 N NE1 . TRP B 2 247 ? 12.216  -37.645 -6.785  1   40.82  ? 243 TRP A NE1 1 
ATOM   4112 C CE2 . TRP B 2 247 ? 11.886  -36.307 -6.766  1   40.05  ? 243 TRP A CE2 1 
ATOM   4113 C CE3 . TRP B 2 247 ? 9.983   -34.893 -7.343  1   36.27  ? 243 TRP A CE3 1 
ATOM   4114 C CZ2 . TRP B 2 247 ? 12.622  -35.198 -6.333  1   39.52  ? 243 TRP A CZ2 1 
ATOM   4115 C CZ3 . TRP B 2 247 ? 10.706  -33.798 -6.902  1   36.93  ? 243 TRP A CZ3 1 
ATOM   4116 C CH2 . TRP B 2 247 ? 12.025  -33.952 -6.418  1   39.4   ? 243 TRP A CH2 1 
ATOM   4117 N N   . ALA B 2 248 ? 7.559   -40.397 -9.96   1   41.56  ? 244 ALA A N   1 
ATOM   4118 C CA  . ALA B 2 248 ? 6.391   -41.254 -10.277 1   43.08  ? 244 ALA A CA  1 
ATOM   4119 C C   . ALA B 2 248 ? 5.44    -41.303 -9.08   1   45.15  ? 244 ALA A C   1 
ATOM   4120 O O   . ALA B 2 248 ? 5.919   -41.41  -7.929  1   48.04  ? 244 ALA A O   1 
ATOM   4121 C CB  . ALA B 2 248 ? 6.859   -42.638 -10.666 1   42.88  ? 244 ALA A CB  1 
ATOM   4122 N N   . ARG B 2 249 ? 4.133   -41.245 -9.327  1   47.1   ? 245 ARG A N   1 
ATOM   4123 C CA  . ARG B 2 249 ? 3.149   -41.361 -8.226  1   47.22  ? 245 ARG A CA  1 
ATOM   4124 C C   . ARG B 2 249 ? 3.301   -42.751 -7.615  1   51.17  ? 245 ARG A C   1 
ATOM   4125 O O   . ARG B 2 249 ? 3.393   -43.73  -8.364  1   54.38  ? 245 ARG A O   1 
ATOM   4126 C CB  . ARG B 2 249 ? 1.69    -41.19  -8.662  1   46.72  ? 245 ARG A CB  1 
ATOM   4127 C CG  . ARG B 2 249 ? 0.682   -41.48  -7.563  1   45.64  ? 245 ARG A CG  1 
ATOM   4128 C CD  . ARG B 2 249 ? -0.738  -41.233 -8.014  1   47.49  ? 245 ARG A CD  1 
ATOM   4129 N NE  . ARG B 2 249 ? -1.25   -39.977 -7.458  1   52.58  ? 245 ARG A NE  1 
ATOM   4130 C CZ  . ARG B 2 249 ? -1.922  -39.877 -6.325  1   51.69  ? 245 ARG A CZ  1 
ATOM   4131 N NH1 . ARG B 2 249 ? -1.798  -38.795 -5.587  1   47.81  ? 245 ARG A NH1 1 
ATOM   4132 N NH2 . ARG B 2 249 ? -2.722  -40.852 -5.939  1   46.32  ? 245 ARG A NH2 1 
ATOM   4133 N N   . GLN B 2 250 ? 3.313   -42.814 -6.295  1   56.68  ? 246 GLN A N   1 
ATOM   4134 C CA  . GLN B 2 250 ? 3.465   -44.125 -5.612  1   61.21  ? 246 GLN A CA  1 
ATOM   4135 C C   . GLN B 2 250 ? 2.086   -44.675 -5.226  1   64.78  ? 246 GLN A C   1 
ATOM   4136 O O   . GLN B 2 250 ? 1.128   -43.871 -5.146  1   56.29  ? 246 GLN A O   1 
ATOM   4137 C CB  . GLN B 2 250 ? 4.314   -43.962 -4.352  1   58.34  ? 246 GLN A CB  1 
ATOM   4138 C CG  . GLN B 2 250 ? 3.582   -43.278 -3.202  1   53.47  ? 246 GLN A CG  1 
ATOM   4139 C CD  . GLN B 2 250 ? 4.397   -43.183 -1.931  1   58.35  ? 246 GLN A CD  1 
ATOM   4140 O OE1 . GLN B 2 250 ? 4.585   -42.101 -1.365  1   62.53  ? 246 GLN A OE1 1 
ATOM   4141 N NE2 . GLN B 2 250 ? 4.886   -44.323 -1.468  1   65.38  ? 246 GLN A NE2 1 
ATOM   4142 N N   . ASP B 2 251 ? 1.978   -45.992 -5.021  1   64.03  ? 247 ASP A N   1 
ATOM   4143 C CA  . ASP B 2 251 ? 0.722   -46.543 -4.536  1   62.66  ? 247 ASP A CA  1 
ATOM   4144 C C   . ASP B 2 251 ? 0.34    -45.779 -3.273  1   57.42  ? 247 ASP A C   1 
ATOM   4145 O O   . ASP B 2 251 ? 1.117   -45.629 -2.338  1   58.94  ? 247 ASP A O   1 
ATOM   4146 C CB  . ASP B 2 251 ? 0.765   -48.058 -4.35   1   75.57  ? 247 ASP A CB  1 
ATOM   4147 C CG  . ASP B 2 251 ? -0.589  -48.768 -4.315  1   92.69  ? 247 ASP A CG  1 
ATOM   4148 O OD1 . ASP B 2 251 ? -1.398  -48.55  -3.367  1   90.55  ? 247 ASP A OD1 1 
ATOM   4149 O OD2 . ASP B 2 251 ? -0.841  -49.547 -5.253  1   99.74  ? 247 ASP A OD2 1 
ATOM   4150 N N   . PHE B 2 252 ? -0.899  -45.31  -3.257  1   54.45  ? 248 PHE A N   1 
ATOM   4151 C CA  . PHE B 2 252 ? -1.456  -44.555 -2.154  1   48.29  ? 248 PHE A CA  1 
ATOM   4152 C C   . PHE B 2 252 ? -1.507  -45.371 -0.855  1   47.16  ? 248 PHE A C   1 
ATOM   4153 O O   . PHE B 2 252 ? -1.62   -44.814 0.241   1   49.12  ? 248 PHE A O   1 
ATOM   4154 C CB  . PHE B 2 252 ? -2.839  -44.106 -2.648  1   49.45  ? 248 PHE A CB  1 
ATOM   4155 C CG  . PHE B 2 252 ? -3.12   -42.778 -1.983  1   46.73  ? 248 PHE A CG  1 
ATOM   4156 C CD1 . PHE B 2 252 ? -2.597  -41.616 -2.545  1   43.57  ? 248 PHE A CD1 1 
ATOM   4157 C CD2 . PHE B 2 252 ? -3.769  -42.705 -0.769  1   44.02  ? 248 PHE A CD2 1 
ATOM   4158 C CE1 . PHE B 2 252 ? -2.784  -40.386 -1.96   1   42.57  ? 248 PHE A CE1 1 
ATOM   4159 C CE2 . PHE B 2 252 ? -3.929  -41.45  -0.178  1   48.05  ? 248 PHE A CE2 1 
ATOM   4160 C CZ  . PHE B 2 252 ? -3.446  -40.298 -0.777  1   41.29  ? 248 PHE A CZ  1 
ATOM   4161 N N   . SER B 2 253 ? -1.517  -46.701 -0.974  1   44.92  ? 249 SER A N   1 
ATOM   4162 C CA  . SER B 2 253 ? -1.515  -47.575 0.184   1   44.23  ? 249 SER A CA  1 
ATOM   4163 C C   . SER B 2 253 ? -0.178  -47.497 0.929   1   46.61  ? 249 SER A C   1 
ATOM   4164 O O   . SER B 2 253 ? -0.087  -47.963 2.072   1   45.06  ? 249 SER A O   1 
ATOM   4165 C CB  . SER B 2 253 ? -1.821  -49.014 -0.223  1   44.36  ? 249 SER A CB  1 
ATOM   4166 O OG  . SER B 2 253 ? -0.728  -49.611 -0.92   1   47.45  ? 249 SER A OG  1 
ATOM   4167 N N   . LYS B 2 254 ? 0.873   -46.972 0.252   1   48.25  ? 250 LYS A N   1 
ATOM   4168 C CA  . LYS B 2 254 ? 2.203   -46.842 0.84    1   48.51  ? 250 LYS A CA  1 
ATOM   4169 C C   . LYS B 2 254 ? 2.325   -45.484 1.533   1   48.79  ? 250 LYS A C   1 
ATOM   4170 O O   . LYS B 2 254 ? 3.173   -45.305 2.395   1   54.49  ? 250 LYS A O   1 
ATOM   4171 C CB  . LYS B 2 254 ? 3.295   -47.086 -0.208  1   46.54  ? 250 LYS A CB  1 
ATOM   4172 C CG  . LYS B 2 254 ? 3.289   -48.505 -0.756  1   47.64  ? 250 LYS A CG  1 
ATOM   4173 C CD  . LYS B 2 254 ? 3.757   -49.525 0.289   1   51.56  ? 250 LYS A CD  1 
ATOM   4174 C CE  . LYS B 2 254 ? 3.679   -50.974 -0.089  1   52.49  ? 250 LYS A CE  1 
ATOM   4175 N NZ  . LYS B 2 254 ? 2.3     -51.297 -0.489  1   53.54  ? 250 LYS A NZ  1 
ATOM   4176 N N   . VAL B 2 255 ? 1.453   -44.538 1.178   1   46.51  ? 251 VAL A N   1 
ATOM   4177 C CA  . VAL B 2 255 ? 1.494   -43.205 1.753   1   44.58  ? 251 VAL A CA  1 
ATOM   4178 C C   . VAL B 2 255 ? 1.113   -43.26  3.225   1   46.12  ? 251 VAL A C   1 
ATOM   4179 O O   . VAL B 2 255 ? 1.837   -42.688 4.038   1   48.19  ? 251 VAL A O   1 
ATOM   4180 C CB  . VAL B 2 255 ? 0.593   -42.206 1.016   1   39.86  ? 251 VAL A CB  1 
ATOM   4181 C CG1 . VAL B 2 255 ? 0.67    -40.842 1.698   1   35.62  ? 251 VAL A CG1 1 
ATOM   4182 C CG2 . VAL B 2 255 ? 1.001   -42.122 -0.46   1   39.65  ? 251 VAL A CG2 1 
ATOM   4183 N N   . VAL B 2 256 ? 0.001   -43.948 3.538   1   43.16  ? 252 VAL A N   1 
ATOM   4184 C CA  . VAL B 2 256 ? -0.444  -44.15  4.913   1   42.15  ? 252 VAL A CA  1 
ATOM   4185 C C   . VAL B 2 256 ? -0.839  -45.607 5.095   1   42.5   ? 252 VAL A C   1 
ATOM   4186 O O   . VAL B 2 256 ? -2.026  -45.945 5.066   1   41.79  ? 252 VAL A O   1 
ATOM   4187 C CB  . VAL B 2 256 ? -1.608  -43.212 5.292   1   42.72  ? 252 VAL A CB  1 
ATOM   4188 C CG1 . VAL B 2 256 ? -2.007  -43.385 6.758   1   42.78  ? 252 VAL A CG1 1 
ATOM   4189 C CG2 . VAL B 2 256 ? -1.25   -41.752 4.985   1   39.58  ? 252 VAL A CG2 1 
ATOM   4190 N N   . PRO B 2 257 ? 0.164   -46.497 5.275   1   42.33  ? 253 PRO A N   1 
ATOM   4191 C CA  . PRO B 2 257 ? -0.054  -47.944 5.289   1   43.16  ? 253 PRO A CA  1 
ATOM   4192 C C   . PRO B 2 257 ? -1.168  -48.485 6.168   1   45.35  ? 253 PRO A C   1 
ATOM   4193 O O   . PRO B 2 257 ? -1.834  -49.405 5.757   1   47.01  ? 253 PRO A O   1 
ATOM   4194 C CB  . PRO B 2 257 ? 1.322   -48.507 5.682   1   44.17  ? 253 PRO A CB  1 
ATOM   4195 C CG  . PRO B 2 257 ? 2.286   -47.446 5.177   1   42.36  ? 253 PRO A CG  1 
ATOM   4196 C CD  . PRO B 2 257 ? 1.59    -46.133 5.408   1   41.64  ? 253 PRO A CD  1 
ATOM   4197 N N   . PRO B 2 258 ? -1.457  -47.961 7.392   1   47.75  ? 254 PRO A N   1 
ATOM   4198 C CA  . PRO B 2 258 ? -2.601  -48.447 8.157   1   49.61  ? 254 PRO A CA  1 
ATOM   4199 C C   . PRO B 2 258 ? -3.944  -47.997 7.584   1   52.67  ? 254 PRO A C   1 
ATOM   4200 O O   . PRO B 2 258 ? -4.957  -48.675 7.848   1   56.09  ? 254 PRO A O   1 
ATOM   4201 C CB  . PRO B 2 258 ? -2.385  -47.898 9.582   1   48.72  ? 254 PRO A CB  1 
ATOM   4202 C CG  . PRO B 2 258 ? -0.938  -47.472 9.603   1   47.43  ? 254 PRO A CG  1 
ATOM   4203 C CD  . PRO B 2 258 ? -0.707  -46.971 8.194   1   46.05  ? 254 PRO A CD  1 
ATOM   4204 N N   . LEU B 2 259 ? -3.966  -46.892 6.83    1   49.82  ? 255 LEU A N   1 
ATOM   4205 C CA  . LEU B 2 259 ? -5.259  -46.351 6.325   1   46.14  ? 255 LEU A CA  1 
ATOM   4206 C C   . LEU B 2 259 ? -6.022  -47.448 5.564   1   48.53  ? 255 LEU A C   1 
ATOM   4207 O O   . LEU B 2 259 ? -5.404  -48.117 4.706   1   48.83  ? 255 LEU A O   1 
ATOM   4208 C CB  . LEU B 2 259 ? -5.067  -45.109 5.456   1   42.74  ? 255 LEU A CB  1 
ATOM   4209 C CG  . LEU B 2 259 ? -6.202  -44.081 5.517   1   45.92  ? 255 LEU A CG  1 
ATOM   4210 C CD1 . LEU B 2 259 ? -6.938  -44.165 6.842   1   48.18  ? 255 LEU A CD1 1 
ATOM   4211 C CD2 . LEU B 2 259 ? -5.689  -42.674 5.281   1   46.39  ? 255 LEU A CD2 1 
ATOM   4212 N N   . ASP B 2 260 ? -7.317  -47.599 5.855   1   48.88  ? 256 ASP A N   1 
ATOM   4213 C CA  . ASP B 2 260 ? -8.153  -48.635 5.188   1   50.24  ? 256 ASP A CA  1 
ATOM   4214 C C   . ASP B 2 260 ? -8.523  -48.183 3.774   1   47.6   ? 256 ASP A C   1 
ATOM   4215 O O   . ASP B 2 260 ? -8.282  -47.004 3.446   1   44.32  ? 256 ASP A O   1 
ATOM   4216 C CB  . ASP B 2 260 ? -9.419  -48.897 5.982   1   51.97  ? 256 ASP A CB  1 
ATOM   4217 C CG  . ASP B 2 260 ? -10.236 -47.651 6.291   1   50.54  ? 256 ASP A CG  1 
ATOM   4218 O OD1 . ASP B 2 260 ? -9.768  -46.839 7.116   1   52.65  ? 256 ASP A OD1 1 
ATOM   4219 O OD2 . ASP B 2 260 ? -11.32  -47.496 5.694   1   49.37  ? 256 ASP A OD2 1 
ATOM   4220 N N   . GLU B 2 261 ? -9.111  -49.083 2.982   1   49.3   ? 257 GLU A N   1 
ATOM   4221 C CA  . GLU B 2 261 ? -9.539  -48.733 1.603   1   50.83  ? 257 GLU A CA  1 
ATOM   4222 C C   . GLU B 2 261 ? -10.353 -47.43  1.639   1   49.64  ? 257 GLU A C   1 
ATOM   4223 O O   . GLU B 2 261 ? -9.942  -46.457 0.974   1   48.65  ? 257 GLU A O   1 
ATOM   4224 C CB  . GLU B 2 261 ? -10.363 -49.865 0.992   1   56.53  ? 257 GLU A CB  1 
ATOM   4225 C CG  . GLU B 2 261 ? -10.838 -49.568 -0.427  1   62.35  ? 257 GLU A CG  1 
ATOM   4226 C CD  . GLU B 2 261 ? -12.266 -49.057 -0.501  1   74.44  ? 257 GLU A CD  1 
ATOM   4227 O OE1 . GLU B 2 261 ? -13.179 -49.803 -0.091  1   74.31  ? 257 GLU A OE1 1 
ATOM   4228 O OE2 . GLU B 2 261 ? -12.462 -47.912 -0.957  1   83.44  ? 257 GLU A OE2 1 
ATOM   4229 N N   . ASP B 2 262 ? -11.476 -47.425 2.365   1   46.5   ? 258 ASP A N   1 
ATOM   4230 C CA  . ASP B 2 262 ? -12.307 -46.227 2.41    1   45.05  ? 258 ASP A CA  1 
ATOM   4231 C C   . ASP B 2 262 ? -11.473 -45.007 2.827   1   42.87  ? 258 ASP A C   1 
ATOM   4232 O O   . ASP B 2 262 ? -11.545 -43.906 2.253   1   39.12  ? 258 ASP A O   1 
ATOM   4233 C CB  . ASP B 2 262 ? -13.5   -46.449 3.323   1   46.19  ? 258 ASP A CB  1 
ATOM   4234 C CG  . ASP B 2 262 ? -14.603 -47.341 2.754   1   52.83  ? 258 ASP A CG  1 
ATOM   4235 O OD1 . ASP B 2 262 ? -14.594 -47.555 1.523   1   55.33  ? 258 ASP A OD1 1 
ATOM   4236 O OD2 . ASP B 2 262 ? -15.466 -47.83  3.544   1   54.06  ? 258 ASP A OD2 1 
ATOM   4237 N N   . GLY B 2 263 ? -10.691 -45.179 3.896   1   41.92  ? 259 GLY A N   1 
ATOM   4238 C CA  . GLY B 2 263 ? -9.824  -44.085 4.31    1   41.15  ? 259 GLY A CA  1 
ATOM   4239 C C   . GLY B 2 263 ? -8.888  -43.634 3.182   1   40     ? 259 GLY A C   1 
ATOM   4240 O O   . GLY B 2 263 ? -8.743  -42.429 2.971   1   39.38  ? 259 GLY A O   1 
ATOM   4241 N N   . ARG B 2 264 ? -8.274  -44.588 2.464   1   39.13  ? 260 ARG A N   1 
ATOM   4242 C CA  . ARG B 2 264 ? -7.372  -44.256 1.37    1   42.2   ? 260 ARG A CA  1 
ATOM   4243 C C   . ARG B 2 264 ? -8.109  -43.444 0.313   1   41.89  ? 260 ARG A C   1 
ATOM   4244 O O   . ARG B 2 264 ? -7.597  -42.42  -0.165  1   41.95  ? 260 ARG A O   1 
ATOM   4245 C CB  . ARG B 2 264 ? -6.767  -45.483 0.673   1   42.4   ? 260 ARG A CB  1 
ATOM   4246 C CG  . ARG B 2 264 ? -5.675  -46.131 1.522   1   44.78  ? 260 ARG A CG  1 
ATOM   4247 C CD  . ARG B 2 264 ? -4.74   -46.979 0.65    1   44.5   ? 260 ARG A CD  1 
ATOM   4248 N NE  . ARG B 2 264 ? -5.374  -48.135 0.001   1   44.86  ? 260 ARG A NE  1 
ATOM   4249 C CZ  . ARG B 2 264 ? -5.81   -49.209 0.65    1   46.21  ? 260 ARG A CZ  1 
ATOM   4250 N NH1 . ARG B 2 264 ? -5.639  -49.343 1.956   1   47.84  ? 260 ARG A NH1 1 
ATOM   4251 N NH2 . ARG B 2 264 ? -6.469  -50.136 -0.007  1   47.15  ? 260 ARG A NH2 1 
ATOM   4252 N N   . SER B 2 265 ? -9.289  -43.95  -0.039  1   39.96  ? 261 SER A N   1 
ATOM   4253 C CA  . SER B 2 265 ? -10.14  -43.302 -1.021  1   40.62  ? 261 SER A CA  1 
ATOM   4254 C C   . SER B 2 265 ? -10.415 -41.846 -0.625  1   38.21  ? 261 SER A C   1 
ATOM   4255 O O   . SER B 2 265 ? -10.222 -40.927 -1.419  1   37.64  ? 261 SER A O   1 
ATOM   4256 C CB  . SER B 2 265 ? -11.425 -44.104 -1.17   1   41.12  ? 261 SER A CB  1 
ATOM   4257 O OG  . SER B 2 265 ? -12.417 -43.325 -1.796  1   42.43  ? 261 SER A OG  1 
ATOM   4258 N N   . LEU B 2 266 ? -10.825 -41.63  0.626   1   35.13  ? 262 LEU A N   1 
ATOM   4259 C CA  . LEU B 2 266 ? -11.131 -40.276 1.04    1   35.52  ? 262 LEU A CA  1 
ATOM   4260 C C   . LEU B 2 266 ? -9.869  -39.412 1.063   1   37.25  ? 262 LEU A C   1 
ATOM   4261 O O   . LEU B 2 266 ? -9.91   -38.243 0.635   1   38.19  ? 262 LEU A O   1 
ATOM   4262 C CB  . LEU B 2 266 ? -11.804 -40.339 2.416   1   36.35  ? 262 LEU A CB  1 
ATOM   4263 C CG  . LEU B 2 266 ? -12.009 -39.012 3.151   1   35.9   ? 262 LEU A CG  1 
ATOM   4264 C CD1 . LEU B 2 266 ? -12.824 -38.004 2.321   1   34.53  ? 262 LEU A CD1 1 
ATOM   4265 C CD2 . LEU B 2 266 ? -12.696 -39.304 4.465   1   36.48  ? 262 LEU A CD2 1 
ATOM   4266 N N   . LEU B 2 267 ? -8.763  -39.954 1.605   1   36.51  ? 263 LEU A N   1 
ATOM   4267 C CA  . LEU B 2 267 ? -7.511  -39.201 1.682   1   35.99  ? 263 LEU A CA  1 
ATOM   4268 C C   . LEU B 2 267 ? -7.031  -38.799 0.287   1   36.54  ? 263 LEU A C   1 
ATOM   4269 O O   . LEU B 2 267 ? -6.667  -37.629 0.071   1   38.09  ? 263 LEU A O   1 
ATOM   4270 C CB  . LEU B 2 267 ? -6.423  -39.98  2.408   1   36.42  ? 263 LEU A CB  1 
ATOM   4271 C CG  . LEU B 2 267 ? -5.106  -39.221 2.571   1   35.01  ? 263 LEU A CG  1 
ATOM   4272 C CD1 . LEU B 2 267 ? -5.37   -37.961 3.388   1   32.9   ? 263 LEU A CD1 1 
ATOM   4273 C CD2 . LEU B 2 267 ? -4.047  -40.096 3.233   1   34.45  ? 263 LEU A CD2 1 
ATOM   4274 N N   . SER B 2 268 ? -7.066  -39.75  -0.656  1   35.2   ? 264 SER A N   1 
ATOM   4275 C CA  . SER B 2 268 ? -6.716  -39.418 -2.038  1   38.74  ? 264 SER A CA  1 
ATOM   4276 C C   . SER B 2 268 ? -7.564  -38.27  -2.592  1   40.88  ? 264 SER A C   1 
ATOM   4277 O O   . SER B 2 268 ? -7.041  -37.437 -3.331  1   44.35  ? 264 SER A O   1 
ATOM   4278 C CB  . SER B 2 268 ? -6.747  -40.606 -2.969  1   39.39  ? 264 SER A CB  1 
ATOM   4279 O OG  . SER B 2 268 ? -8.038  -41.194 -3.011  1   46.1   ? 264 SER A OG  1 
ATOM   4280 N N   . GLN B 2 269 ? -8.85   -38.198 -2.211  1   37.43  ? 265 GLN A N   1 
ATOM   4281 C CA  . GLN B 2 269 ? -9.713  -37.195 -2.803  1   35.47  ? 265 GLN A CA  1 
ATOM   4282 C C   . GLN B 2 269 ? -9.475  -35.855 -2.139  1   35.65  ? 265 GLN A C   1 
ATOM   4283 O O   . GLN B 2 269 ? -9.661  -34.825 -2.777  1   39.34  ? 265 GLN A O   1 
ATOM   4284 C CB  . GLN B 2 269 ? -11.166 -37.649 -2.761  1   35.64  ? 265 GLN A CB  1 
ATOM   4285 C CG  . GLN B 2 269 ? -11.418 -38.856 -3.647  1   37.56  ? 265 GLN A CG  1 
ATOM   4286 C CD  . GLN B 2 269 ? -12.824 -39.37  -3.439  1   44.23  ? 265 GLN A CD  1 
ATOM   4287 O OE1 . GLN B 2 269 ? -13.042 -40.473 -2.915  1   45.04  ? 265 GLN A OE1 1 
ATOM   4288 N NE2 . GLN B 2 269 ? -13.802 -38.541 -3.794  1   41.84  ? 265 GLN A NE2 1 
ATOM   4289 N N   . MET B 2 270 ? -9      -35.855 -0.892  1   34.65  ? 266 MET A N   1 
ATOM   4290 C CA  . MET B 2 270 ? -8.627  -34.606 -0.249  1   34.5   ? 266 MET A CA  1 
ATOM   4291 C C   . MET B 2 270 ? -7.311  -34.048 -0.789  1   40.57  ? 266 MET A C   1 
ATOM   4292 O O   . MET B 2 270 ? -7.137  -32.818 -0.814  1   43.7   ? 266 MET A O   1 
ATOM   4293 C CB  . MET B 2 270 ? -8.572  -34.753 1.273   1   33.19  ? 266 MET A CB  1 
ATOM   4294 C CG  . MET B 2 270 ? -9.956  -35.115 1.827   1   34.5   ? 266 MET A CG  1 
ATOM   4295 S SD  . MET B 2 270 ? -9.973  -35.589 3.57    1   36.3   ? 266 MET A SD  1 
ATOM   4296 C CE  . MET B 2 270 ? -10.08  -33.976 4.346   1   28.49  ? 266 MET A CE  1 
ATOM   4297 N N   . LEU B 2 271 ? -6.401  -34.937 -1.23   1   37.93  ? 267 LEU A N   1 
ATOM   4298 C CA  . LEU B 2 271 ? -5.069  -34.518 -1.662  1   38.24  ? 267 LEU A CA  1 
ATOM   4299 C C   . LEU B 2 271 ? -4.972  -34.509 -3.194  1   42.09  ? 267 LEU A C   1 
ATOM   4300 O O   . LEU B 2 271 ? -3.877  -34.613 -3.758  1   39.41  ? 267 LEU A O   1 
ATOM   4301 C CB  . LEU B 2 271 ? -4.008  -35.428 -1.044  1   32.98  ? 267 LEU A CB  1 
ATOM   4302 C CG  . LEU B 2 271 ? -3.981  -35.466 0.485   1   35.03  ? 267 LEU A CG  1 
ATOM   4303 C CD1 . LEU B 2 271 ? -2.976  -36.462 1.03    1   34.74  ? 267 LEU A CD1 1 
ATOM   4304 C CD2 . LEU B 2 271 ? -3.639  -34.119 1.061   1   34.13  ? 267 LEU A CD2 1 
ATOM   4305 N N   . HIS B 2 272 ? -6.108  -34.39  -3.883  1   39.23  ? 268 HIS A N   1 
ATOM   4306 C CA  . HIS B 2 272 ? -6.047  -34.335 -5.34   1   42.45  ? 268 HIS A CA  1 
ATOM   4307 C C   . HIS B 2 272 ? -5.338  -33.043 -5.768  1   42.09  ? 268 HIS A C   1 
ATOM   4308 O O   . HIS B 2 272 ? -5.579  -31.956 -5.21   1   42.15  ? 268 HIS A O   1 
ATOM   4309 C CB  . HIS B 2 272 ? -7.465  -34.377 -5.915  1   45.4   ? 268 HIS A CB  1 
ATOM   4310 C CG  . HIS B 2 272 ? -7.52   -34.791 -7.326  1   53.88  ? 268 HIS A CG  1 
ATOM   4311 N ND1 . HIS B 2 272 ? -8.115  -35.98  -7.697  1   57.21  ? 268 HIS A ND1 1 
ATOM   4312 C CD2 . HIS B 2 272 ? -7.064  -34.207 -8.467  1   60.21  ? 268 HIS A CD2 1 
ATOM   4313 C CE1 . HIS B 2 272 ? -8.047  -36.089 -9.028  1   61.53  ? 268 HIS A CE1 1 
ATOM   4314 N NE2 . HIS B 2 272 ? -7.395  -35.033 -9.511  1   63.96  ? 268 HIS A NE2 1 
ATOM   4315 N N   . TYR B 2 273 ? -4.449  -33.164 -6.755  1   40.5   ? 269 TYR A N   1 
ATOM   4316 C CA  . TYR B 2 273 ? -3.662  -32.029 -7.208  1   41.07  ? 269 TYR A CA  1 
ATOM   4317 C C   . TYR B 2 273 ? -4.588  -30.9   -7.678  1   39.87  ? 269 TYR A C   1 
ATOM   4318 O O   . TYR B 2 273 ? -4.391  -29.733 -7.334  1   44.84  ? 269 TYR A O   1 
ATOM   4319 C CB  . TYR B 2 273 ? -2.631  -32.391 -8.292  1   36.14  ? 269 TYR A CB  1 
ATOM   4320 C CG  . TYR B 2 273 ? -1.308  -32.878 -7.744  1   36.54  ? 269 TYR A CG  1 
ATOM   4321 C CD1 . TYR B 2 273 ? -0.464  -31.997 -7.073  1   36.86  ? 269 TYR A CD1 1 
ATOM   4322 C CD2 . TYR B 2 273 ? -0.918  -34.209 -7.838  1   36.74  ? 269 TYR A CD2 1 
ATOM   4323 C CE1 . TYR B 2 273 ? 0.753   -32.403 -6.55   1   35.04  ? 269 TYR A CE1 1 
ATOM   4324 C CE2 . TYR B 2 273 ? 0.3     -34.631 -7.312  1   38.58  ? 269 TYR A CE2 1 
ATOM   4325 C CZ  . TYR B 2 273 ? 1.145   -33.725 -6.672  1   38.02  ? 269 TYR A CZ  1 
ATOM   4326 O OH  . TYR B 2 273 ? 2.367   -34.103 -6.155  1   38.94  ? 269 TYR A OH  1 
ATOM   4327 N N   . ASP B 2 274 ? -5.496  -31.245 -8.576  1   35.98  ? 270 ASP A N   1 
ATOM   4328 C CA  . ASP B 2 274 ? -6.339  -30.276 -9.258  1   41.55  ? 270 ASP A CA  1 
ATOM   4329 C C   . ASP B 2 274 ? -7.32   -29.692 -8.24   1   41.23  ? 270 ASP A C   1 
ATOM   4330 O O   . ASP B 2 274 ? -8.13   -30.421 -7.67   1   43.75  ? 270 ASP A O   1 
ATOM   4331 C CB  . ASP B 2 274 ? -7.092  -30.948 -10.406 1   40.53  ? 270 ASP A CB  1 
ATOM   4332 C CG  . ASP B 2 274 ? -7.859  -30.003 -11.31  1   43.42  ? 270 ASP A CG  1 
ATOM   4333 O OD1 . ASP B 2 274 ? -8.044  -28.846 -10.878 1   45.21  ? 270 ASP A OD1 1 
ATOM   4334 O OD2 . ASP B 2 274 ? -8.244  -30.418 -12.443 1   47.5   ? 270 ASP A OD2 1 
ATOM   4335 N N   . PRO B 2 275 ? -7.269  -28.39  -7.898  1   41.06  ? 271 PRO A N   1 
ATOM   4336 C CA  . PRO B 2 275 ? -8.16   -27.862 -6.862  1   40.39  ? 271 PRO A CA  1 
ATOM   4337 C C   . PRO B 2 275 ? -9.627  -28.087 -7.243  1   39.73  ? 271 PRO A C   1 
ATOM   4338 O O   . PRO B 2 275 ? -10.446 -28.246 -6.336  1   42.15  ? 271 PRO A O   1 
ATOM   4339 C CB  . PRO B 2 275 ? -7.815  -26.376 -6.727  1   37.25  ? 271 PRO A CB  1 
ATOM   4340 C CG  . PRO B 2 275 ? -6.496  -26.265 -7.409  1   39.99  ? 271 PRO A CG  1 
ATOM   4341 C CD  . PRO B 2 275 ? -6.446  -27.347 -8.508  1   40.5   ? 271 PRO A CD  1 
ATOM   4342 N N   . ASN B 2 276 ? -9.934  -28.13  -8.556  1   40.23  ? 272 ASN A N   1 
ATOM   4343 C CA  . ASN B 2 276 ? -11.297 -28.357 -9.036  1   45.6   ? 272 ASN A CA  1 
ATOM   4344 C C   . ASN B 2 276 ? -11.786 -29.791 -8.789  1   45.91  ? 272 ASN A C   1 
ATOM   4345 O O   . ASN B 2 276 ? -12.98  -29.978 -8.63   1   43.58  ? 272 ASN A O   1 
ATOM   4346 C CB  . ASN B 2 276 ? -11.499 -28.087 -10.529 1   45.02  ? 272 ASN A CB  1 
ATOM   4347 C CG  . ASN B 2 276 ? -11.069 -26.707 -10.971 1   47.77  ? 272 ASN A CG  1 
ATOM   4348 O OD1 . ASN B 2 276 ? -11.178 -25.717 -10.239 1   47.9   ? 272 ASN A OD1 1 
ATOM   4349 N ND2 . ASN B 2 276 ? -10.534 -26.616 -12.171 1   50.96  ? 272 ASN A ND2 1 
ATOM   4350 N N   . LYS B 2 277 ? -10.851 -30.743 -8.722  1   44.31  ? 273 LYS A N   1 
ATOM   4351 C CA  . LYS B 2 277 ? -11.213 -32.161 -8.461  1   47.41  ? 273 LYS A CA  1 
ATOM   4352 C C   . LYS B 2 277 ? -11.078 -32.452 -6.96   1   42.55  ? 273 LYS A C   1 
ATOM   4353 O O   . LYS B 2 277 ? -11.597 -33.497 -6.511  1   42.76  ? 273 LYS A O   1 
ATOM   4354 C CB  . LYS B 2 277 ? -10.317 -33.088 -9.287  1   50.34  ? 273 LYS A CB  1 
ATOM   4355 C CG  . LYS B 2 277 ? -10.43  -32.901 -10.791 1   67.92  ? 273 LYS A CG  1 
ATOM   4356 C CD  . LYS B 2 277 ? -11.809 -33.239 -11.343 1   85.56  ? 273 LYS A CD  1 
ATOM   4357 C CE  . LYS B 2 277 ? -11.907 -33.126 -12.834 1   94.54  ? 273 LYS A CE  1 
ATOM   4358 N NZ  . LYS B 2 277 ? -13.25  -33.434 -13.334 1   77.74  ? 273 LYS A NZ  1 
ATOM   4359 N N   . ARG B 2 278 ? -10.407 -31.565 -6.219  1   40.36  ? 274 ARG A N   1 
ATOM   4360 C CA  . ARG B 2 278 ? -10.294 -31.74  -4.748  1   38.71  ? 274 ARG A CA  1 
ATOM   4361 C C   . ARG B 2 278 ? -11.709 -31.867 -4.159  1   39.63  ? 274 ARG A C   1 
ATOM   4362 O O   . ARG B 2 278 ? -12.576 -31.047 -4.525  1   35.95  ? 274 ARG A O   1 
ATOM   4363 C CB  . ARG B 2 278 ? -9.531  -30.561 -4.136  1   35.41  ? 274 ARG A CB  1 
ATOM   4364 C CG  . ARG B 2 278 ? -8.936  -30.867 -2.771  1   36.16  ? 274 ARG A CG  1 
ATOM   4365 C CD  . ARG B 2 278 ? -7.664  -30.077 -2.518  1   37.09  ? 274 ARG A CD  1 
ATOM   4366 N NE  . ARG B 2 278 ? -6.891  -29.839 -3.741  1   38.93  ? 274 ARG A NE  1 
ATOM   4367 C CZ  . ARG B 2 278 ? -5.877  -28.989 -3.816  1   37.21  ? 274 ARG A CZ  1 
ATOM   4368 N NH1 . ARG B 2 278 ? -5.586  -28.22  -2.783  1   31.67  ? 274 ARG A NH1 1 
ATOM   4369 N NH2 . ARG B 2 278 ? -5.159  -28.911 -4.921  1   36.9   ? 274 ARG A NH2 1 
ATOM   4370 N N   . ILE B 2 279 ? -11.932 -32.85  -3.282  1   36.33  ? 275 ILE A N   1 
ATOM   4371 C CA  . ILE B 2 279 ? -13.303 -33.084 -2.729  1   36.42  ? 275 ILE A CA  1 
ATOM   4372 C C   . ILE B 2 279 ? -13.713 -31.89  -1.849  1   35.65  ? 275 ILE A C   1 
ATOM   4373 O O   . ILE B 2 279 ? -12.817 -31.26  -1.249  1   37.31  ? 275 ILE A O   1 
ATOM   4374 C CB  . ILE B 2 279 ? -13.361 -34.423 -1.966  1   35.28  ? 275 ILE A CB  1 
ATOM   4375 C CG1 . ILE B 2 279 ? -14.799 -34.906 -1.772  1   34.22  ? 275 ILE A CG1 1 
ATOM   4376 C CG2 . ILE B 2 279 ? -12.61  -34.344 -0.636  1   31.2   ? 275 ILE A CG2 1 
ATOM   4377 C CD1 . ILE B 2 279 ? -14.906 -36.313 -1.214  1   34.17  ? 275 ILE A CD1 1 
ATOM   4378 N N   . SER B 2 280 ? -15.01  -31.568 -1.804  1   34.09  ? 276 SER A N   1 
ATOM   4379 C CA  . SER B 2 280 ? -15.487 -30.496 -0.932  1   32.91  ? 276 SER A CA  1 
ATOM   4380 C C   . SER B 2 280 ? -15.786 -31.057 0.464   1   33.35  ? 276 SER A C   1 
ATOM   4381 O O   . SER B 2 280 ? -16.103 -32.241 0.583   1   35.51  ? 276 SER A O   1 
ATOM   4382 C CB  . SER B 2 280 ? -16.737 -29.827 -1.518  1   34.2   ? 276 SER A CB  1 
ATOM   4383 O OG  . SER B 2 280 ? -17.824 -30.74  -1.43   1   34.79  ? 276 SER A OG  1 
ATOM   4384 N N   . ALA B 2 281 ? -15.677 -30.226 1.524   1   33.24  ? 277 ALA A N   1 
ATOM   4385 C CA  . ALA B 2 281 ? -16.09  -30.681 2.855   1   35.9   ? 277 ALA A CA  1 
ATOM   4386 C C   . ALA B 2 281 ? -17.513 -31.243 2.802   1   36.71  ? 277 ALA A C   1 
ATOM   4387 O O   . ALA B 2 281 ? -17.834 -32.308 3.366   1   36.92  ? 277 ALA A O   1 
ATOM   4388 C CB  . ALA B 2 281 ? -16.012 -29.551 3.865   1   33.85  ? 277 ALA A CB  1 
ATOM   4389 N N   . LYS B 2 282 ? -18.394 -30.508 2.111   1   38.03  ? 278 LYS A N   1 
ATOM   4390 C CA  . LYS B 2 282 ? -19.803 -30.904 2.034   1   37.4   ? 278 LYS A CA  1 
ATOM   4391 C C   . LYS B 2 282 ? -19.944 -32.326 1.486   1   38.71  ? 278 LYS A C   1 
ATOM   4392 O O   . LYS B 2 282 ? -20.731 -33.098 1.996   1   40.06  ? 278 LYS A O   1 
ATOM   4393 C CB  . LYS B 2 282 ? -20.552 -29.81  1.258   1   38.05  ? 278 LYS A CB  1 
ATOM   4394 C CG  . LYS B 2 282 ? -22.014 -29.966 1.003   1   42.16  ? 278 LYS A CG  1 
ATOM   4395 C CD  . LYS B 2 282 ? -22.666 -28.859 0.174   1   42.35  ? 278 LYS A CD  1 
ATOM   4396 C CE  . LYS B 2 282 ? -22.81  -27.557 0.918   1   42.67  ? 278 LYS A CE  1 
ATOM   4397 N NZ  . LYS B 2 282 ? -23.789 -26.655 0.28    1   43.11  ? 278 LYS A NZ  1 
ATOM   4398 N N   . ALA B 2 283 ? -19.153 -32.727 0.482   1   44.89  ? 279 ALA A N   1 
ATOM   4399 C CA  . ALA B 2 283 ? -19.344 -34.037 -0.18   1   44.93  ? 279 ALA A CA  1 
ATOM   4400 C C   . ALA B 2 283 ? -18.649 -35.159 0.588   1   41.78  ? 279 ALA A C   1 
ATOM   4401 O O   . ALA B 2 283 ? -19.144 -36.298 0.635   1   45.02  ? 279 ALA A O   1 
ATOM   4402 C CB  . ALA B 2 283 ? -18.82  -34.013 -1.612  1   40.41  ? 279 ALA A CB  1 
ATOM   4403 N N   . ALA B 2 284 ? -17.505 -34.794 1.174   1   36.36  ? 280 ALA A N   1 
ATOM   4404 C CA  . ALA B 2 284 ? -16.742 -35.664 2.054   1   36.22  ? 280 ALA A CA  1 
ATOM   4405 C C   . ALA B 2 284 ? -17.604 -36.193 3.203   1   36.82  ? 280 ALA A C   1 
ATOM   4406 O O   . ALA B 2 284 ? -17.439 -37.351 3.586   1   38.72  ? 280 ALA A O   1 
ATOM   4407 C CB  . ALA B 2 284 ? -15.531 -34.936 2.542   1   32.26  ? 280 ALA A CB  1 
ATOM   4408 N N   . LEU B 2 285 ? -18.568 -35.394 3.699   1   35.85  ? 281 LEU A N   1 
ATOM   4409 C CA  . LEU B 2 285 ? -19.457 -35.877 4.763   1   36.51  ? 281 LEU A CA  1 
ATOM   4410 C C   . LEU B 2 285 ? -20.174 -37.171 4.383   1   38.86  ? 281 LEU A C   1 
ATOM   4411 O O   . LEU B 2 285 ? -20.529 -37.944 5.28    1   42.41  ? 281 LEU A O   1 
ATOM   4412 C CB  . LEU B 2 285 ? -20.466 -34.816 5.194   1   35.95  ? 281 LEU A CB  1 
ATOM   4413 C CG  . LEU B 2 285 ? -19.865 -33.582 5.882   1   34.27  ? 281 LEU A CG  1 
ATOM   4414 C CD1 . LEU B 2 285 ? -21     -32.6   6.115   1   35.32  ? 281 LEU A CD1 1 
ATOM   4415 C CD2 . LEU B 2 285 ? -19.215 -34.008 7.177   1   31.48  ? 281 LEU A CD2 1 
ATOM   4416 N N   . ALA B 2 286 ? -20.395 -37.404 3.074   1   37.88  ? 282 ALA A N   1 
ATOM   4417 C CA  . ALA B 2 286 ? -21.124 -38.593 2.637   1   38.67  ? 282 ALA A CA  1 
ATOM   4418 C C   . ALA B 2 286 ? -20.192 -39.762 2.296   1   39.07  ? 282 ALA A C   1 
ATOM   4419 O O   . ALA B 2 286 ? -20.661 -40.839 1.946   1   38.91  ? 282 ALA A O   1 
ATOM   4420 C CB  . ALA B 2 286 ? -22.049 -38.259 1.488   1   39.29  ? 282 ALA A CB  1 
ATOM   4421 N N   . HIS B 2 287 ? -18.87  -39.587 2.496   1   38.15  ? 283 HIS A N   1 
ATOM   4422 C CA  . HIS B 2 287 ? -17.952 -40.642 2.1     1   38.64  ? 283 HIS A CA  1 
ATOM   4423 C C   . HIS B 2 287 ? -18.197 -41.881 2.966   1   38.89  ? 283 HIS A C   1 
ATOM   4424 O O   . HIS B 2 287 ? -18.497 -41.76  4.147   1   37.32  ? 283 HIS A O   1 
ATOM   4425 C CB  . HIS B 2 287 ? -16.498 -40.159 2.144   1   36.93  ? 283 HIS A CB  1 
ATOM   4426 C CG  . HIS B 2 287 ? -15.529 -41.082 1.491   1   41.08  ? 283 HIS A CG  1 
ATOM   4427 N ND1 . HIS B 2 287 ? -15.241 -42.331 2.021   1   41.89  ? 283 HIS A ND1 1 
ATOM   4428 C CD2 . HIS B 2 287 ? -14.746 -40.955 0.374   1   40.1   ? 283 HIS A CD2 1 
ATOM   4429 C CE1 . HIS B 2 287 ? -14.36  -42.946 1.222   1   40.23  ? 283 HIS A CE1 1 
ATOM   4430 N NE2 . HIS B 2 287 ? -14.063 -42.14  0.208   1   38.82  ? 283 HIS A NE2 1 
ATOM   4431 N N   . PRO B 2 288 ? -18.15  -43.098 2.374   1   40.84  ? 284 PRO A N   1 
ATOM   4432 C CA  . PRO B 2 288 ? -18.325 -44.339 3.128   1   41.6   ? 284 PRO A CA  1 
ATOM   4433 C C   . PRO B 2 288 ? -17.423 -44.508 4.348   1   42.75  ? 284 PRO A C   1 
ATOM   4434 O O   . PRO B 2 288 ? -17.803 -45.21  5.295   1   44.72  ? 284 PRO A O   1 
ATOM   4435 C CB  . PRO B 2 288 ? -18.163 -45.482 2.122   1   41.79  ? 284 PRO A CB  1 
ATOM   4436 C CG  . PRO B 2 288 ? -17.982 -44.821 0.77    1   40.58  ? 284 PRO A CG  1 
ATOM   4437 C CD  . PRO B 2 288 ? -17.996 -43.317 0.924   1   39.25  ? 284 PRO A CD  1 
ATOM   4438 N N   . PHE B 2 289 ? -16.234 -43.858 4.329   1   43.32  ? 285 PHE A N   1 
ATOM   4439 C CA  . PHE B 2 289 ? -15.329 -43.901 5.47    1   41.9   ? 285 PHE A CA  1 
ATOM   4440 C C   . PHE B 2 289 ? -16.084 -43.625 6.78    1   41.56  ? 285 PHE A C   1 
ATOM   4441 O O   . PHE B 2 289 ? -15.735 -44.162 7.829   1   42.67  ? 285 PHE A O   1 
ATOM   4442 C CB  . PHE B 2 289 ? -14.19  -42.905 5.283   1   41.86  ? 285 PHE A CB  1 
ATOM   4443 C CG  . PHE B 2 289 ? -13.146 -42.959 6.391   1   45.58  ? 285 PHE A CG  1 
ATOM   4444 C CD1 . PHE B 2 289 ? -12.341 -44.08  6.571   1   44.81  ? 285 PHE A CD1 1 
ATOM   4445 C CD2 . PHE B 2 289 ? -12.994 -41.901 7.281   1   46.42  ? 285 PHE A CD2 1 
ATOM   4446 C CE1 . PHE B 2 289 ? -11.401 -44.121 7.584   1   44.96  ? 285 PHE A CE1 1 
ATOM   4447 C CE2 . PHE B 2 289 ? -12.026 -41.941 8.278   1   46.13  ? 285 PHE A CE2 1 
ATOM   4448 C CZ  . PHE B 2 289 ? -11.222 -43.043 8.42    1   43.88  ? 285 PHE A CZ  1 
ATOM   4449 N N   . PHE B 2 290 ? -17.116 -42.783 6.726   1   39.43  ? 286 PHE A N   1 
ATOM   4450 C CA  . PHE B 2 290 ? -17.821 -42.361 7.927   1   40.91  ? 286 PHE A CA  1 
ATOM   4451 C C   . PHE B 2 290 ? -19.01  -43.262 8.245   1   46.08  ? 286 PHE A C   1 
ATOM   4452 O O   . PHE B 2 290 ? -19.707 -42.971 9.221   1   50.7   ? 286 PHE A O   1 
ATOM   4453 C CB  . PHE B 2 290 ? -18.28  -40.9   7.835   1   37.76  ? 286 PHE A CB  1 
ATOM   4454 C CG  . PHE B 2 290 ? -17.119 -39.948 7.579   1   36.29  ? 286 PHE A CG  1 
ATOM   4455 C CD1 . PHE B 2 290 ? -16.133 -39.781 8.541   1   34.07  ? 286 PHE A CD1 1 
ATOM   4456 C CD2 . PHE B 2 290 ? -17.022 -39.232 6.391   1   35.3   ? 286 PHE A CD2 1 
ATOM   4457 C CE1 . PHE B 2 290 ? -15.106 -38.896 8.318   1   33.85  ? 286 PHE A CE1 1 
ATOM   4458 C CE2 . PHE B 2 290 ? -15.962 -38.368 6.167   1   34.95  ? 286 PHE A CE2 1 
ATOM   4459 C CZ  . PHE B 2 290 ? -14.996 -38.212 7.133   1   33.6   ? 286 PHE A CZ  1 
ATOM   4460 N N   . GLN B 2 291 ? -19.219 -44.357 7.495   1   49.1   ? 287 GLN A N   1 
ATOM   4461 C CA  . GLN B 2 291 ? -20.461 -45.101 7.598   1   52.18  ? 287 GLN A CA  1 
ATOM   4462 C C   . GLN B 2 291 ? -20.77  -45.559 9.023   1   57.33  ? 287 GLN A C   1 
ATOM   4463 O O   . GLN B 2 291 ? -21.955 -45.744 9.345   1   63.78  ? 287 GLN A O   1 
ATOM   4464 C CB  . GLN B 2 291 ? -20.618 -46.253 6.612   1   58.72  ? 287 GLN A CB  1 
ATOM   4465 C CG  . GLN B 2 291 ? -19.836 -47.508 6.971   1   70.72  ? 287 GLN A CG  1 
ATOM   4466 C CD  . GLN B 2 291 ? -19.729 -48.478 5.809   1   81.77  ? 287 GLN A CD  1 
ATOM   4467 O OE1 . GLN B 2 291 ? -20.363 -49.535 5.819   1   93.87  ? 287 GLN A OE1 1 
ATOM   4468 N NE2 . GLN B 2 291 ? -18.97  -48.13  4.774   1   72.88  ? 287 GLN A NE2 1 
ATOM   4469 N N   A ASP B 2 292 ? -19.728 -45.718 9.857   0.5 55.52  ? 288 ASP A N   1 
ATOM   4470 N N   B ASP B 2 292 ? -19.754 -45.763 9.882   0.5 55.56  ? 288 ASP A N   1 
ATOM   4471 C CA  A ASP B 2 292 ? -19.905 -46.316 11.175  0.5 56.62  ? 288 ASP A CA  1 
ATOM   4472 C CA  B ASP B 2 292 ? -20.063 -46.301 11.207  0.5 56.28  ? 288 ASP A CA  1 
ATOM   4473 C C   A ASP B 2 292 ? -19.764 -45.278 12.289  0.5 55.4   ? 288 ASP A C   1 
ATOM   4474 C C   B ASP B 2 292 ? -19.819 -45.267 12.305  0.5 55.22  ? 288 ASP A C   1 
ATOM   4475 O O   A ASP B 2 292 ? -19.802 -45.64  13.462  0.5 56.42  ? 288 ASP A O   1 
ATOM   4476 O O   B ASP B 2 292 ? -19.823 -45.622 13.481  0.5 56.15  ? 288 ASP A O   1 
ATOM   4477 C CB  A ASP B 2 292 ? -19.05  -47.569 11.335  0.5 56.83  ? 288 ASP A CB  1 
ATOM   4478 C CB  B ASP B 2 292 ? -19.404 -47.65  11.492  0.5 56.58  ? 288 ASP A CB  1 
ATOM   4479 C CG  A ASP B 2 292 ? -17.601 -47.443 10.889  0.5 55.4   ? 288 ASP A CG  1 
ATOM   4480 C CG  B ASP B 2 292 ? -19.959 -48.858 10.745  0.5 57.71  ? 288 ASP A CG  1 
ATOM   4481 O OD1 A ASP B 2 292 ? -17.227 -46.339 10.408  0.5 52.89  ? 288 ASP A OD1 1 
ATOM   4482 O OD1 B ASP B 2 292 ? -21.204 -49.049 10.738  0.5 57.37  ? 288 ASP A OD1 1 
ATOM   4483 O OD2 A ASP B 2 292 ? -16.869 -48.454 11.015  0.5 54.06  ? 288 ASP A OD2 1 
ATOM   4484 O OD2 B ASP B 2 292 ? -19.136 -49.603 10.173  0.5 56.86  ? 288 ASP A OD2 1 
ATOM   4485 N N   . VAL B 2 293 ? -19.672 -43.995 11.92   1   53.96  ? 289 VAL A N   1 
ATOM   4486 C CA  . VAL B 2 293 ? -19.281 -42.938 12.83   1   54.88  ? 289 VAL A CA  1 
ATOM   4487 C C   . VAL B 2 293 ? -20.146 -42.842 14.075  1   65.17  ? 289 VAL A C   1 
ATOM   4488 O O   . VAL B 2 293 ? -21.382 -42.87  14.035  1   58.65  ? 289 VAL A O   1 
ATOM   4489 C CB  . VAL B 2 293 ? -19.122 -41.546 12.233  1   52.67  ? 289 VAL A CB  1 
ATOM   4490 C CG1 . VAL B 2 293 ? -19.245 -40.477 13.3    1   57.62  ? 289 VAL A CG1 1 
ATOM   4491 C CG2 . VAL B 2 293 ? -17.767 -41.414 11.664  1   48.25  ? 289 VAL A CG2 1 
ATOM   4492 N N   . THR B 2 294 ? -19.389 -42.68  15.167  1   83.39  ? 290 THR A N   1 
ATOM   4493 C CA  . THR B 2 294 ? -19.83  -42.713 16.547  1   98.24  ? 290 THR A CA  1 
ATOM   4494 C C   . THR B 2 294 ? -19.742 -41.281 17.068  1   95.59  ? 290 THR A C   1 
ATOM   4495 O O   . THR B 2 294 ? -18.923 -40.49  16.587  1   83.62  ? 290 THR A O   1 
ATOM   4496 C CB  . THR B 2 294 ? -18.982 -43.726 17.337  1   105.21 ? 290 THR A CB  1 
ATOM   4497 O OG1 . THR B 2 294 ? -19.313 -43.665 18.724  1   123.86 ? 290 THR A OG1 1 
ATOM   4498 C CG2 . THR B 2 294 ? -17.479 -43.571 17.165  1   104.31 ? 290 THR A CG2 1 
ATOM   4499 N N   A LYS B 2 295 ? -20.629 -40.972 18.022  0.5 93.21  ? 291 LYS A N   1 
ATOM   4500 N N   B LYS B 2 295 ? -20.629 -40.954 18.026  0.5 95.83  ? 291 LYS A N   1 
ATOM   4501 C CA  A LYS B 2 295 ? -20.736 -39.669 18.668  0.5 89.45  ? 291 LYS A CA  1 
ATOM   4502 C CA  B LYS B 2 295 ? -20.692 -39.671 18.726  0.5 93.75  ? 291 LYS A CA  1 
ATOM   4503 C C   A LYS B 2 295 ? -22.027 -38.977 18.22   0.5 89.72  ? 291 LYS A C   1 
ATOM   4504 C C   B LYS B 2 295 ? -21.949 -38.893 18.285  0.5 94.3   ? 291 LYS A C   1 
ATOM   4505 O O   A LYS B 2 295 ? -22.185 -38.627 17.049  0.5 82.97  ? 291 LYS A O   1 
ATOM   4506 O O   B LYS B 2 295 ? -22.013 -38.376 17.165  0.5 90.14  ? 291 LYS A O   1 
ATOM   4507 C CB  A LYS B 2 295 ? -19.483 -38.776 18.604  0.5 69.36  ? 291 LYS A CB  1 
ATOM   4508 C CB  B LYS B 2 295 ? -19.336 -38.934 18.859  0.5 73.63  ? 291 LYS A CB  1 
ATOM   4509 C CG  A LYS B 2 295 ? -18.341 -39.208 19.509  0.5 63.01  ? 291 LYS A CG  1 
ATOM   4510 C CG  B LYS B 2 295 ? -18.325 -39.375 19.963  0.5 67.12  ? 291 LYS A CG  1 
ATOM   4511 C CD  A LYS B 2 295 ? -18.299 -38.666 20.931  0.5 57.73  ? 291 LYS A CD  1 
ATOM   4512 C CD  B LYS B 2 295 ? -17.227 -40.402 19.649  0.5 65.1   ? 291 LYS A CD  1 
ATOM   4513 C CE  A LYS B 2 295 ? -19.363 -39.183 21.811  0.5 60.66  ? 291 LYS A CE  1 
ATOM   4514 C CE  B LYS B 2 295 ? -16.339 -40.938 20.772  0.5 58.17  ? 291 LYS A CE  1 
ATOM   4515 N NZ  A LYS B 2 295 ? -19.395 -38.485 23.097  0.5 57.78  ? 291 LYS A NZ  1 
ATOM   4516 N NZ  B LYS B 2 295 ? -15.838 -39.949 21.74   0.5 52.48  ? 291 LYS A NZ  1 
ATOM   4517 N N   . PRO B 2 296 ? -23.004 -38.803 19.141  1   88.97  ? 292 PRO A N   1 
ATOM   4518 C CA  . PRO B 2 296 ? -24.055 -37.791 18.966  1   91.27  ? 292 PRO A CA  1 
ATOM   4519 C C   . PRO B 2 296 ? -23.459 -36.409 18.718  1   83.52  ? 292 PRO A C   1 
ATOM   4520 O O   . PRO B 2 296 ? -22.461 -36.081 19.334  1   84.34  ? 292 PRO A O   1 
ATOM   4521 C CB  . PRO B 2 296 ? -24.854 -37.831 20.297  1   94.25  ? 292 PRO A CB  1 
ATOM   4522 C CG  . PRO B 2 296 ? -24.595 -39.228 20.866  1   95.03  ? 292 PRO A CG  1 
ATOM   4523 C CD  . PRO B 2 296 ? -23.228 -39.663 20.324  1   93.08  ? 292 PRO A CD  1 
ATOM   4524 N N   . VAL B 2 297 ? -24.071 -35.705 17.792  1   87.02  ? 293 VAL A N   1 
ATOM   4525 C CA  . VAL B 2 297 ? -23.592 -34.368 17.381  1   94.05  ? 293 VAL A CA  1 
ATOM   4526 C C   . VAL B 2 297 ? -23.406 -33.428 18.58   1   101.86 ? 293 VAL A C   1 
ATOM   4527 O O   . VAL B 2 297 ? -24.286 -33.397 19.456  1   96.93  ? 293 VAL A O   1 
ATOM   4528 C CB  . VAL B 2 297 ? -24.638 -33.927 16.329  1   90.01  ? 293 VAL A CB  1 
ATOM   4529 C CG1 . VAL B 2 297 ? -25.144 -32.514 16.571  1   81.78  ? 293 VAL A CG1 1 
ATOM   4530 C CG2 . VAL B 2 297 ? -24.092 -34.057 14.915  1   76.56  ? 293 VAL A CG2 1 
ATOM   4531 N N   . PRO B 2 298 ? -22.241 -32.727 18.704  1   116.01 ? 294 PRO A N   1 
ATOM   4532 C CA  . PRO B 2 298 ? -22.026 -31.785 19.789  1   111.71 ? 294 PRO A CA  1 
ATOM   4533 C C   . PRO B 2 298 ? -23.13  -30.77  19.673  1   108.81 ? 294 PRO A C   1 
ATOM   4534 O O   . PRO B 2 298 ? -23.573 -30.44  18.555  1   104.22 ? 294 PRO A O   1 
ATOM   4535 C CB  . PRO B 2 298 ? -20.644 -31.169 19.546  1   103.38 ? 294 PRO A CB  1 
ATOM   4536 C CG  . PRO B 2 298 ? -19.935 -32.201 18.711  1   97.74  ? 294 PRO A CG  1 
ATOM   4537 C CD  . PRO B 2 298 ? -21.036 -32.768 17.837  1   105.66 ? 294 PRO A CD  1 
ATOM   4538 N N   . HIS B 2 299 ? -23.568 -30.251 20.811  1   113.99 ? 295 HIS A N   1 
ATOM   4539 C CA  . HIS B 2 299 ? -24.73  -29.34  20.765  1   109.24 ? 295 HIS A CA  1 
ATOM   4540 C C   . HIS B 2 299 ? -24.272 -27.909 20.516  1   107.19 ? 295 HIS A C   1 
ATOM   4541 O O   . HIS B 2 299 ? -23.145 -27.502 20.828  1   91.33  ? 295 HIS A O   1 
ATOM   4542 C CB  . HIS B 2 299 ? -25.518 -29.271 22.077  1   111.12 ? 295 HIS A CB  1 
ATOM   4543 C CG  . HIS B 2 299 ? -26.178 -30.511 22.565  1   130.44 ? 295 HIS A CG  1 
ATOM   4544 N ND1 . HIS B 2 299 ? -27.312 -31.046 21.996  1   144.05 ? 295 HIS A ND1 1 
ATOM   4545 C CD2 . HIS B 2 299 ? -25.895 -31.279 23.618  1   132.14 ? 295 HIS A CD2 1 
ATOM   4546 C CE1 . HIS B 2 299 ? -27.674 -32.119 22.677  1   137.66 ? 295 HIS A CE1 1 
ATOM   4547 N NE2 . HIS B 2 299 ? -26.827 -32.276 23.668  1   141.57 ? 295 HIS A NE2 1 
ATOM   4548 N N   . LEU B 2 300 ? -25.219 -27.143 20.014  1   110.28 ? 296 LEU A N   1 
ATOM   4549 C CA  . LEU B 2 300 ? -24.92  -25.722 19.855  1   119.12 ? 296 LEU A CA  1 
ATOM   4550 C C   . LEU B 2 300 ? -24.582 -25.153 21.243  1   132.98 ? 296 LEU A C   1 
ATOM   4551 O O   . LEU B 2 300 ? -25.027 -25.689 22.268  1   154.34 ? 296 LEU A O   1 
ATOM   4552 C CB  . LEU B 2 300 ? -26.152 -25.04  19.241  1   106.06 ? 296 LEU A CB  1 
ATOM   4553 C CG  . LEU B 2 300 ? -26.589 -25.421 17.817  1   94.41  ? 296 LEU A CG  1 
ATOM   4554 C CD1 . LEU B 2 300 ? -27.906 -24.787 17.369  1   91.02  ? 296 LEU A CD1 1 
ATOM   4555 C CD2 . LEU B 2 300 ? -25.481 -25.217 16.781  1   82.79  ? 296 LEU A CD2 1 
ATOM   4556 N N   . ARG B 2 301 ? -23.832 -24.06  21.272  1   116.3  ? 297 ARG A N   1 
ATOM   4557 C CA  . ARG B 2 301 ? -23.524 -23.434 22.575  1   105.3  ? 297 ARG A CA  1 
ATOM   4558 C C   . ARG B 2 301 ? -24.137 -22.031 22.612  1   94.42  ? 297 ARG A C   1 
ATOM   4559 O O   . ARG B 2 301 ? -24.466 -21.505 21.532  1   81.57  ? 297 ARG A O   1 
ATOM   4560 C CB  . ARG B 2 301 ? -22.001 -23.455 22.739  1   108.66 ? 297 ARG A CB  1 
ATOM   4561 C CG  . ARG B 2 301 ? -21.478 -24.75  23.344  1   102.38 ? 297 ARG A CG  1 
ATOM   4562 C CD  . ARG B 2 301 ? -20.495 -24.501 24.475  1   105.64 ? 297 ARG A CD  1 
ATOM   4563 N NE  . ARG B 2 301 ? -21.09  -23.767 25.596  1   101.67 ? 297 ARG A NE  1 
ATOM   4564 C CZ  . ARG B 2 301 ? -20.583 -22.656 26.113  1   96.14  ? 297 ARG A CZ  1 
ATOM   4565 N NH1 . ARG B 2 301 ? -20.073 -22.664 27.331  1   74.59  ? 297 ARG A NH1 1 
ATOM   4566 N NH2 . ARG B 2 301 ? -20.59  -21.541 25.408  1   89.17  ? 297 ARG A NH2 1 
ATOM   4567 N N   . LEU B 2 302 ? -24.334 -21.524 23.836  1   94.99  ? 298 LEU A N   1 
ATOM   4568 C CA  . LEU B 2 302 ? -24.897 -20.169 24.06   1   92.2   ? 298 LEU A CA  1 
ATOM   4569 C C   . LEU B 2 302 ? -23.727 -19.249 24.416  1   85.9   ? 298 LEU A C   1 
ATOM   4570 O O   . LEU B 2 302 ? -22.967 -19.651 25.321  1   77.67  ? 298 LEU A O   1 
ATOM   4571 C CB  . LEU B 2 302 ? -25.877 -20.214 25.23   1   88.73  ? 298 LEU A CB  1 
ATOM   4572 C CG  . LEU B 2 302 ? -27.155 -21.042 25.08   1   80.94  ? 298 LEU A CG  1 
ATOM   4573 C CD1 . LEU B 2 302 ? -27.976 -21.131 26.341  1   80.58  ? 298 LEU A CD1 1 
ATOM   4574 C CD2 . LEU B 2 302 ? -27.982 -20.513 23.931  1   79.98  ? 298 LEU A CD2 1 
ATOM   4575 N N   . GLY C 1 1   ? -15.043 -23.905 -12.002 1   48.99  ? 171 GLY B N   1 
ATOM   4576 C CA  . GLY C 1 1   ? -14.346 -24.808 -11.061 1   49.32  ? 171 GLY B CA  1 
ATOM   4577 C C   . GLY C 1 1   ? -14.431 -24.243 -9.646  1   47.63  ? 171 GLY B C   1 
ATOM   4578 O O   . GLY C 1 1   ? -15.222 -23.319 -9.38   1   45.55  ? 171 GLY B O   1 
ATOM   4579 N N   . VAL C 1 2   ? -13.562 -24.756 -8.768  1   45.45  ? 172 VAL B N   1 
ATOM   4580 C CA  . VAL C 1 2   ? -13.603 -24.393 -7.358  1   44.6   ? 172 VAL B CA  1 
ATOM   4581 C C   . VAL C 1 2   ? -13.533 -22.876 -7.099  1   43.78  ? 172 VAL B C   1 
ATOM   4582 O O   . VAL C 1 2   ? -14.058 -22.428 -6.068  1   43.85  ? 172 VAL B O   1 
ATOM   4583 C CB  . VAL C 1 2   ? -12.535 -25.204 -6.599  1   45.53  ? 172 VAL B CB  1 
ATOM   4584 C CG1 . VAL C 1 2   ? -11.137 -24.606 -6.818  1   42.78  ? 172 VAL B CG1 1 
ATOM   4585 C CG2 . VAL C 1 2   ? -12.925 -25.397 -5.125  1   40.99  ? 172 VAL B CG2 1 
ATOM   4586 N N   . ASN C 1 3   ? -12.956 -22.06  -8.015  1   43.41  ? 173 ASN B N   1 
ATOM   4587 C CA  . ASN C 1 3   ? -12.886 -20.61  -7.772  1   41.86  ? 173 ASN B CA  1 
ATOM   4588 C C   . ASN C 1 3   ? -14.272 -19.971 -7.759  1   43.51  ? 173 ASN B C   1 
ATOM   4589 O O   . ASN C 1 3   ? -14.413 -18.836 -7.303  1   42.99  ? 173 ASN B O   1 
ATOM   4590 C CB  . ASN C 1 3   ? -11.973 -19.844 -8.727  1   42.43  ? 173 ASN B CB  1 
ATOM   4591 C CG  . ASN C 1 3   ? -10.535 -20.34  -8.678  1   45.43  ? 173 ASN B CG  1 
ATOM   4592 O OD1 . ASN C 1 3   ? -10.045 -20.776 -7.623  1   46.29  ? 173 ASN B OD1 1 
ATOM   4593 N ND2 . ASN C 1 3   ? -9.851  -20.367 -9.813  1   43.06  ? 173 ASN B ND2 1 
ATOM   4594 N N   . GLU C 1 4   ? -15.272 -20.706 -8.277  1   45.68  ? 174 GLU B N   1 
ATOM   4595 C CA  . GLU C 1 4   ? -16.678 -20.321 -8.263  1   48.41  ? 174 GLU B CA  1 
ATOM   4596 C C   . GLU C 1 4   ? -17.471 -21.164 -7.268  1   46.06  ? 174 GLU B C   1 
ATOM   4597 O O   . GLU C 1 4   ? -18.691 -21.088 -7.272  1   44.45  ? 174 GLU B O   1 
ATOM   4598 C CB  . GLU C 1 4   ? -17.309 -20.607 -9.626  1   50.48  ? 174 GLU B CB  1 
ATOM   4599 C CG  . GLU C 1 4   ? -16.592 -19.849 -10.738 1   60.64  ? 174 GLU B CG  1 
ATOM   4600 C CD  . GLU C 1 4   ? -17.048 -20.176 -12.15  1   69.61  ? 174 GLU B CD  1 
ATOM   4601 O OE1 . GLU C 1 4   ? -17.907 -21.063 -12.351 1   73.5   ? 174 GLU B OE1 1 
ATOM   4602 O OE2 . GLU C 1 4   ? -16.526 -19.502 -13.061 1   75.89  ? 174 GLU B OE2 1 
ATOM   4603 N N   . VAL C 1 5   ? -16.776 -21.974 -6.461  1   42.3   ? 175 VAL B N   1 
ATOM   4604 C CA  . VAL C 1 5   ? -17.342 -22.72  -5.355  1   43.03  ? 175 VAL B CA  1 
ATOM   4605 C C   . VAL C 1 5   ? -18.692 -23.305 -5.755  1   44.2   ? 175 VAL B C   1 
ATOM   4606 O O   . VAL C 1 5   ? -19.722 -22.965 -5.169  1   45.26  ? 175 VAL B O   1 
ATOM   4607 C CB  . VAL C 1 5   ? -17.418 -21.875 -4.064  1   41.22  ? 175 VAL B CB  1 
ATOM   4608 C CG1 . VAL C 1 5   ? -16.015 -21.584 -3.558  1   42.97  ? 175 VAL B CG1 1 
ATOM   4609 C CG2 . VAL C 1 5   ? -18.213 -20.574 -4.19   1   37.12  ? 175 VAL B CG2 1 
ATOM   4610 N N   . PRO C 1 6   ? -18.729 -24.215 -6.749  1   46.17  ? 176 PRO B N   1 
ATOM   4611 C CA  . PRO C 1 6   ? -19.997 -24.809 -7.196  1   47.2   ? 176 PRO B CA  1 
ATOM   4612 C C   . PRO C 1 6   ? -20.798 -25.375 -6.019  1   48.52  ? 176 PRO B C   1 
ATOM   4613 O O   . PRO C 1 6   ? -22.018 -25.239 -5.99   1   48.29  ? 176 PRO B O   1 
ATOM   4614 C CB  . PRO C 1 6   ? -19.577 -25.924 -8.211  1   45.38  ? 176 PRO B CB  1 
ATOM   4615 C CG  . PRO C 1 6   ? -18.058 -26.058 -8.07   1   44.32  ? 176 PRO B CG  1 
ATOM   4616 C CD  . PRO C 1 6   ? -17.557 -24.751 -7.471  1   45.95  ? 176 PRO B CD  1 
ATOM   4617 N N   . ASP C 1 7   ? -20.096 -26.019 -5.06   1   47.48  ? 177 ASP B N   1 
ATOM   4618 C CA  . ASP C 1 7   ? -20.71  -26.742 -3.956  1   45.31  ? 177 ASP B CA  1 
ATOM   4619 C C   . ASP C 1 7   ? -21.275 -25.8   -2.868  1   44.55  ? 177 ASP B C   1 
ATOM   4620 O O   . ASP C 1 7   ? -21.895 -26.283 -1.914  1   43.69  ? 177 ASP B O   1 
ATOM   4621 C CB  . ASP C 1 7   ? -19.764 -27.787 -3.378  1   43.42  ? 177 ASP B CB  1 
ATOM   4622 C CG  . ASP C 1 7   ? -19.8   -29.156 -4.039  1   46.68  ? 177 ASP B CG  1 
ATOM   4623 O OD1 . ASP C 1 7   ? -20.305 -29.227 -5.153  1   48.37  ? 177 ASP B OD1 1 
ATOM   4624 O OD2 . ASP C 1 7   ? -19.368 -30.173 -3.432  1   47.02  ? 177 ASP B OD2 1 
ATOM   4625 N N   . TYR C 1 8   ? -21.044 -24.477 -2.974  1   39.43  ? 178 TYR B N   1 
ATOM   4626 C CA  . TYR C 1 8   ? -21.305 -23.565 -1.872  1   38.22  ? 178 TYR B CA  1 
ATOM   4627 C C   . TYR C 1 8   ? -21.966 -22.279 -2.374  1   38.3   ? 178 TYR B C   1 
ATOM   4628 O O   . TYR C 1 8   ? -22.458 -21.505 -1.549  1   38.52  ? 178 TYR B O   1 
ATOM   4629 C CB  . TYR C 1 8   ? -20.019 -23.238 -1.07   1   36.6   ? 178 TYR B CB  1 
ATOM   4630 C CG  . TYR C 1 8   ? -19.354 -24.415 -0.378  1   37.01  ? 178 TYR B CG  1 
ATOM   4631 C CD1 . TYR C 1 8   ? -19.875 -24.925 0.803   1   38.1   ? 178 TYR B CD1 1 
ATOM   4632 C CD2 . TYR C 1 8   ? -18.273 -25.099 -0.941  1   39.59  ? 178 TYR B CD2 1 
ATOM   4633 C CE1 . TYR C 1 8   ? -19.314 -26.023 1.445   1   37.26  ? 178 TYR B CE1 1 
ATOM   4634 C CE2 . TYR C 1 8   ? -17.701 -26.21  -0.309  1   39.24  ? 178 TYR B CE2 1 
ATOM   4635 C CZ  . TYR C 1 8   ? -18.213 -26.664 0.904   1   38.52  ? 178 TYR B CZ  1 
ATOM   4636 O OH  . TYR C 1 8   ? -17.755 -27.794 1.554   1   39.81  ? 178 TYR B OH  1 
ATOM   4637 N N   . HIS C 1 9   ? -21.993 -22.019 -3.7    1   39.41  ? 179 HIS B N   1 
ATOM   4638 C CA  . HIS C 1 9   ? -22.433 -20.706 -4.188  1   41.84  ? 179 HIS B CA  1 
ATOM   4639 C C   . HIS C 1 9   ? -23.897 -20.437 -3.796  1   41.45  ? 179 HIS B C   1 
ATOM   4640 O O   . HIS C 1 9   ? -24.238 -19.314 -3.438  1   40.3   ? 179 HIS B O   1 
ATOM   4641 C CB  . HIS C 1 9   ? -22.11  -20.45  -5.677  1   48.48  ? 179 HIS B CB  1 
ATOM   4642 C CG  . HIS C 1 9   ? -22.993 -21.157 -6.652  1   64.55  ? 179 HIS B CG  1 
ATOM   4643 N ND1 . HIS C 1 9   ? -22.812 -22.486 -7.021  1   80.66  ? 179 HIS B ND1 1 
ATOM   4644 C CD2 . HIS C 1 9   ? -24.111 -20.752 -7.282  1   66.05  ? 179 HIS B CD2 1 
ATOM   4645 C CE1 . HIS C 1 9   ? -23.78  -22.876 -7.859  1   68.66  ? 179 HIS B CE1 1 
ATOM   4646 N NE2 . HIS C 1 9   ? -24.579 -21.833 -8.023  1   74.57  ? 179 HIS B NE2 1 
ATOM   4647 N N   . GLU C 1 10  ? -24.77  -21.451 -3.884  1   42.2   ? 180 GLU B N   1 
ATOM   4648 C CA  . GLU C 1 10  ? -26.176 -21.296 -3.498  1   43.61  ? 180 GLU B CA  1 
ATOM   4649 C C   . GLU C 1 10  ? -26.306 -20.955 -2.002  1   42.92  ? 180 GLU B C   1 
ATOM   4650 O O   . GLU C 1 10  ? -26.94  -19.94  -1.684  1   41.61  ? 180 GLU B O   1 
ATOM   4651 C CB  . GLU C 1 10  ? -26.978 -22.569 -3.739  1   48.93  ? 180 GLU B CB  1 
ATOM   4652 C CG  . GLU C 1 10  ? -28.004 -22.519 -4.865  1   63.16  ? 180 GLU B CG  1 
ATOM   4653 C CD  . GLU C 1 10  ? -28.995 -23.683 -4.708  1   75.24  ? 180 GLU B CD  1 
ATOM   4654 O OE1 . GLU C 1 10  ? -29.838 -23.702 -3.769  1   72.95  ? 180 GLU B OE1 1 
ATOM   4655 O OE2 . GLU C 1 10  ? -28.908 -24.611 -5.548  1   86.43  ? 180 GLU B OE2 1 
ATOM   4656 N N   . ASP C 1 11  ? -25.684 -21.762 -1.101  1   38.84  ? 181 ASP B N   1 
ATOM   4657 C CA  . ASP C 1 11  ? -25.679 -21.473 0.333   1   40.06  ? 181 ASP B CA  1 
ATOM   4658 C C   . ASP C 1 11  ? -25.199 -20.047 0.582   1   38.63  ? 181 ASP B C   1 
ATOM   4659 O O   . ASP C 1 11  ? -25.789 -19.308 1.353   1   39.68  ? 181 ASP B O   1 
ATOM   4660 C CB  . ASP C 1 11  ? -24.791 -22.4   1.152   1   40.82  ? 181 ASP B CB  1 
ATOM   4661 C CG  . ASP C 1 11  ? -25.229 -23.855 1.261   1   47.88  ? 181 ASP B CG  1 
ATOM   4662 O OD1 . ASP C 1 11  ? -26.403 -24.162 0.906   1   48.69  ? 181 ASP B OD1 1 
ATOM   4663 O OD2 . ASP C 1 11  ? -24.404 -24.68  1.72    1   48.79  ? 181 ASP B OD2 1 
ATOM   4664 N N   . ILE C 1 12  ? -24.122 -19.649 -0.102  1   38.88  ? 182 ILE B N   1 
ATOM   4665 C CA  . ILE C 1 12  ? -23.571 -18.328 0.104   1   35.86  ? 182 ILE B CA  1 
ATOM   4666 C C   . ILE C 1 12  ? -24.564 -17.267 -0.354  1   34.98  ? 182 ILE B C   1 
ATOM   4667 O O   . ILE C 1 12  ? -24.77  -16.273 0.34    1   36.66  ? 182 ILE B O   1 
ATOM   4668 C CB  . ILE C 1 12  ? -22.207 -18.204 -0.586  1   33.99  ? 182 ILE B CB  1 
ATOM   4669 C CG1 . ILE C 1 12  ? -21.146 -19.068 0.144   1   34.24  ? 182 ILE B CG1 1 
ATOM   4670 C CG2 . ILE C 1 12  ? -21.817 -16.732 -0.656  1   32.96  ? 182 ILE B CG2 1 
ATOM   4671 C CD1 . ILE C 1 12  ? -19.92  -19.418 -0.689  1   33.42  ? 182 ILE B CD1 1 
ATOM   4672 N N   . HIS C 1 13  ? -25.115 -17.414 -1.558  1   35.17  ? 183 HIS B N   1 
ATOM   4673 C CA  . HIS C 1 13  ? -26.115 -16.456 -2.025  1   36.99  ? 183 HIS B CA  1 
ATOM   4674 C C   . HIS C 1 13  ? -27.231 -16.3   -0.975  1   36.6   ? 183 HIS B C   1 
ATOM   4675 O O   . HIS C 1 13  ? -27.553 -15.182 -0.578  1   36.85  ? 183 HIS B O   1 
ATOM   4676 C CB  . HIS C 1 13  ? -26.709 -16.9   -3.365  1   38.24  ? 183 HIS B CB  1 
ATOM   4677 C CG  . HIS C 1 13  ? -27.823 -16.014 -3.795  1   40.59  ? 183 HIS B CG  1 
ATOM   4678 N ND1 . HIS C 1 13  ? -27.559 -14.737 -4.255  1   41.88  ? 183 HIS B ND1 1 
ATOM   4679 C CD2 . HIS C 1 13  ? -29.171 -16.157 -3.812  1   38.92  ? 183 HIS B CD2 1 
ATOM   4680 C CE1 . HIS C 1 13  ? -28.699 -14.122 -4.534  1   39.18  ? 183 HIS B CE1 1 
ATOM   4681 N NE2 . HIS C 1 13  ? -29.669 -14.98  -4.316  1   40.12  ? 183 HIS B NE2 1 
ATOM   4682 N N   . THR C 1 14  ? -27.786 -17.425 -0.494  1   37.39  ? 184 THR B N   1 
ATOM   4683 C CA  . THR C 1 14  ? -28.863 -17.432 0.494   1   39.5   ? 184 THR B CA  1 
ATOM   4684 C C   . THR C 1 14  ? -28.443 -16.691 1.759   1   42.89  ? 184 THR B C   1 
ATOM   4685 O O   . THR C 1 14  ? -29.229 -15.899 2.276   1   44.99  ? 184 THR B O   1 
ATOM   4686 C CB  . THR C 1 14  ? -29.253 -18.863 0.86    1   40.9   ? 184 THR B CB  1 
ATOM   4687 O OG1 . THR C 1 14  ? -29.905 -19.425 -0.274  1   41.41  ? 184 THR B OG1 1 
ATOM   4688 C CG2 . THR C 1 14  ? -30.133 -18.943 2.098   1   40.44  ? 184 THR B CG2 1 
ATOM   4689 N N   . TYR C 1 15  ? -27.206 -16.935 2.202   1   40.65  ? 185 TYR B N   1 
ATOM   4690 C CA  . TYR C 1 15  ? -26.674 -16.256 3.412   1   38.33  ? 185 TYR B CA  1 
ATOM   4691 C C   . TYR C 1 15  ? -26.648 -14.755 3.169   1   38.46  ? 185 TYR B C   1 
ATOM   4692 O O   . TYR C 1 15  ? -27.236 -14     3.969   1   40.03  ? 185 TYR B O   1 
ATOM   4693 C CB  . TYR C 1 15  ? -25.271 -16.801 3.687   1   39.46  ? 185 TYR B CB  1 
ATOM   4694 C CG  . TYR C 1 15  ? -24.71  -16.377 5.035   1   40.02  ? 185 TYR B CG  1 
ATOM   4695 C CD1 . TYR C 1 15  ? -25.492 -16.442 6.18    1   42.35  ? 185 TYR B CD1 1 
ATOM   4696 C CD2 . TYR C 1 15  ? -23.409 -15.907 5.159   1   39.04  ? 185 TYR B CD2 1 
ATOM   4697 C CE1 . TYR C 1 15  ? -24.999 -16.055 7.413   1   45.8   ? 185 TYR B CE1 1 
ATOM   4698 C CE2 . TYR C 1 15  ? -22.903 -15.52  6.388   1   42.6   ? 185 TYR B CE2 1 
ATOM   4699 C CZ  . TYR C 1 15  ? -23.7   -15.593 7.516   1   49.51  ? 185 TYR B CZ  1 
ATOM   4700 O OH  . TYR C 1 15  ? -23.226 -15.218 8.736   1   51.51  ? 185 TYR B OH  1 
ATOM   4701 N N   . LEU C 1 16  ? -25.986 -14.331 2.089   1   36.95  ? 186 LEU B N   1 
ATOM   4702 C CA  . LEU C 1 16  ? -25.881 -12.883 1.769   1   35.55  ? 186 LEU B CA  1 
ATOM   4703 C C   . LEU C 1 16  ? -27.287 -12.266 1.731   1   41.15  ? 186 LEU B C   1 
ATOM   4704 O O   . LEU C 1 16  ? -27.459 -11.152 2.268   1   45.76  ? 186 LEU B O   1 
ATOM   4705 C CB  . LEU C 1 16  ? -25.161 -12.706 0.435   1   32.18  ? 186 LEU B CB  1 
ATOM   4706 C CG  . LEU C 1 16  ? -23.685 -13.114 0.405   1   32.67  ? 186 LEU B CG  1 
ATOM   4707 C CD1 . LEU C 1 16  ? -23.043 -12.639 -0.886  1   30.1   ? 186 LEU B CD1 1 
ATOM   4708 C CD2 . LEU C 1 16  ? -22.939 -12.574 1.613   1   29.86  ? 186 LEU B CD2 1 
ATOM   4709 N N   . ARG C 1 17  ? -28.278 -12.952 1.177   1   38.32  ? 187 ARG B N   1 
ATOM   4710 C CA  . ARG C 1 17  ? -29.628 -12.348 1.065   1   39.72  ? 187 ARG B CA  1 
ATOM   4711 C C   . ARG C 1 17  ? -30.161 -12.051 2.473   1   41.32  ? 187 ARG B C   1 
ATOM   4712 O O   . ARG C 1 17  ? -30.791 -11.011 2.667   1   44.57  ? 187 ARG B O   1 
ATOM   4713 C CB  . ARG C 1 17  ? -30.52  -13.296 0.263   1   36.17  ? 187 ARG B CB  1 
ATOM   4714 C CG  . ARG C 1 17  ? -30.239 -13.293 -1.231  1   36.2   ? 187 ARG B CG  1 
ATOM   4715 C CD  . ARG C 1 17  ? -30.608 -11.978 -1.887  1   35.54  ? 187 ARG B CD  1 
ATOM   4716 N NE  . ARG C 1 17  ? -32.044 -11.692 -1.82   1   35.99  ? 187 ARG B NE  1 
ATOM   4717 C CZ  . ARG C 1 17  ? -32.981 -12.327 -2.506  1   37.19  ? 187 ARG B CZ  1 
ATOM   4718 N NH1 . ARG C 1 17  ? -32.712 -12.83  -3.694  1   38.98  ? 187 ARG B NH1 1 
ATOM   4719 N NH2 . ARG C 1 17  ? -34.194 -12.442 -2.007  1   34.5   ? 187 ARG B NH2 1 
ATOM   4720 N N   . GLU C 1 18  ? -29.908 -12.943 3.412   1   41.25  ? 188 GLU B N   1 
ATOM   4721 C CA  . GLU C 1 18  ? -30.327 -12.774 4.82    1   45.69  ? 188 GLU B CA  1 
ATOM   4722 C C   . GLU C 1 18  ? -29.486 -11.707 5.529   1   47.59  ? 188 GLU B C   1 
ATOM   4723 O O   . GLU C 1 18  ? -29.997 -10.909 6.297   1   48.71  ? 188 GLU B O   1 
ATOM   4724 C CB  . GLU C 1 18  ? -30.23  -14.125 5.541   1   45.6   ? 188 GLU B CB  1 
ATOM   4725 C CG  . GLU C 1 18  ? -29.862 -14.057 7.019   1   51.98  ? 188 GLU B CG  1 
ATOM   4726 C CD  . GLU C 1 18  ? -29.878 -15.334 7.847   1   62.51  ? 188 GLU B CD  1 
ATOM   4727 O OE1 . GLU C 1 18  ? -29.509 -16.415 7.342   1   65.55  ? 188 GLU B OE1 1 
ATOM   4728 O OE2 . GLU C 1 18  ? -30.249 -15.241 9.03    1   58.91  ? 188 GLU B OE2 1 
ATOM   4729 N N   . MET C 1 19  ? -28.233 -11.682 5.169   1   46.89  ? 189 MET B N   1 
ATOM   4730 C CA  . MET C 1 19  ? -27.282 -10.75  5.83    1   48.75  ? 189 MET B CA  1 
ATOM   4731 C C   . MET C 1 19  ? -27.572 -9.306  5.387   1   48.07  ? 189 MET B C   1 
ATOM   4732 O O   . MET C 1 19  ? -27.6   -8.417  6.264   1   49.55  ? 189 MET B O   1 
ATOM   4733 C CB  . MET C 1 19  ? -25.836 -11.131 5.495   1   45.67  ? 189 MET B CB  1 
ATOM   4734 C CG  . MET C 1 19  ? -25.359 -12.386 6.194   1   48.74  ? 189 MET B CG  1 
ATOM   4735 S SD  . MET C 1 19  ? -26.031 -12.508 7.863   1   55.99  ? 189 MET B SD  1 
ATOM   4736 C CE  . MET C 1 19  ? -24.792 -11.572 8.77    1   59.65  ? 189 MET B CE  1 
ATOM   4737 N N   . GLU C 1 20  ? -27.774 -9.082  4.085   1   45     ? 190 GLU B N   1 
ATOM   4738 C CA  . GLU C 1 20  ? -28.031 -7.733  3.594   1   43.03  ? 190 GLU B CA  1 
ATOM   4739 C C   . GLU C 1 20  ? -29.171 -7.066  4.363   1   43.74  ? 190 GLU B C   1 
ATOM   4740 O O   . GLU C 1 20  ? -29.168 -5.854  4.56    1   45.78  ? 190 GLU B O   1 
ATOM   4741 C CB  . GLU C 1 20  ? -28.263 -7.636  2.087   1   41.52  ? 190 GLU B CB  1 
ATOM   4742 C CG  . GLU C 1 20  ? -29.447 -8.433  1.535   1   42.41  ? 190 GLU B CG  1 
ATOM   4743 C CD  . GLU C 1 20  ? -29.644 -8.171  0.047   1   43.17  ? 190 GLU B CD  1 
ATOM   4744 O OE1 . GLU C 1 20  ? -28.836 -7.359  -0.495  1   44.44  ? 190 GLU B OE1 1 
ATOM   4745 O OE2 . GLU C 1 20  ? -30.57  -8.735  -0.57   1   42.05  ? 190 GLU B OE2 1 
ATOM   4746 N N   . VAL C 1 21  ? -30.154 -7.839  4.81    1   45.11  ? 191 VAL B N   1 
ATOM   4747 C CA  . VAL C 1 21  ? -31.316 -7.266  5.55    1   45.63  ? 191 VAL B CA  1 
ATOM   4748 C C   . VAL C 1 21  ? -30.841 -6.853  6.948   1   47.82  ? 191 VAL B C   1 
ATOM   4749 O O   . VAL C 1 21  ? -31.207 -5.763  7.401   1   53.31  ? 191 VAL B O   1 
ATOM   4750 C CB  . VAL C 1 21  ? -32.489 -8.261  5.599   1   46.37  ? 191 VAL B CB  1 
ATOM   4751 C CG1 . VAL C 1 21  ? -33.662 -7.736  6.412   1   41.15  ? 191 VAL B CG1 1 
ATOM   4752 C CG2 . VAL C 1 21  ? -32.935 -8.667  4.201   1   43.35  ? 191 VAL B CG2 1 
ATOM   4753 N N   . LYS C 1 22  ? -30.026 -7.685  7.577   1   50.1   ? 192 LYS B N   1 
ATOM   4754 C CA  . LYS C 1 22  ? -29.458 -7.352  8.901   1   52.05  ? 192 LYS B CA  1 
ATOM   4755 C C   . LYS C 1 22  ? -28.523 -6.147  8.761   1   53.4   ? 192 LYS B C   1 
ATOM   4756 O O   . LYS C 1 22  ? -28.526 -5.286  9.654   1   56.85  ? 192 LYS B O   1 
ATOM   4757 C CB  . LYS C 1 22  ? -28.706 -8.579  9.417   1   59.25  ? 192 LYS B CB  1 
ATOM   4758 C CG  . LYS C 1 22  ? -28.111 -8.448  10.806  1   64     ? 192 LYS B CG  1 
ATOM   4759 C CD  . LYS C 1 22  ? -27.416 -9.713  11.29   1   69.18  ? 192 LYS B CD  1 
ATOM   4760 C CE  . LYS C 1 22  ? -26.822 -9.538  12.65   1   75.07  ? 192 LYS B CE  1 
ATOM   4761 N NZ  . LYS C 1 22  ? -26.153 -10.752 13.121  1   73.6   ? 192 LYS B NZ  1 
ATOM   4762 N N   . CYS C 1 23  ? -27.824 -6.025  7.699   1   50.73  ? 193 CYS B N   1 
ATOM   4763 C CA  . CYS C 1 23  ? -26.795 -5.002  7.539   1   52.7   ? 193 CYS B CA  1 
ATOM   4764 C C   . CYS C 1 23  ? -27.323 -3.748  6.844   1   52.88  ? 193 CYS B C   1 
ATOM   4765 O O   . CYS C 1 23  ? -26.508 -2.92   6.4     1   52.27  ? 193 CYS B O   1 
ATOM   4766 C CB  . CYS C 1 23  ? -25.582 -5.505  6.748   1   46.95  ? 193 CYS B CB  1 
ATOM   4767 S SG  . CYS C 1 23  ? -24.539 -6.679  7.687   1   60.69  ? 193 CYS B SG  1 
ATOM   4768 N N   . LYS C 1 24  ? -28.654 -3.639  6.724   1   48.43  ? 194 LYS B N   1 
ATOM   4769 C CA  . LYS C 1 24  ? -29.283 -2.546  5.992   1   49.24  ? 194 LYS B CA  1 
ATOM   4770 C C   . LYS C 1 24  ? -29.283 -1.272  6.846   1   51.53  ? 194 LYS B C   1 
ATOM   4771 O O   . LYS C 1 24  ? -29.579 -1.308  8.041   1   52.81  ? 194 LYS B O   1 
ATOM   4772 C CB  . LYS C 1 24  ? -30.706 -2.896  5.556   1   53.97  ? 194 LYS B CB  1 
ATOM   4773 C CG  . LYS C 1 24  ? -31.334 -1.861  4.641   1   62.23  ? 194 LYS B CG  1 
ATOM   4774 C CD  . LYS C 1 24  ? -32.746 -2.195  4.166   1   70.35  ? 194 LYS B CD  1 
ATOM   4775 C CE  . LYS C 1 24  ? -33.198 -1.267  3.05    1   70.77  ? 194 LYS B CE  1 
ATOM   4776 N NZ  . LYS C 1 24  ? -34.55  -1.561  2.559   1   75.47  ? 194 LYS B NZ  1 
ATOM   4777 N N   . PRO C 1 25  ? -28.914 -0.089  6.291   1   49.73  ? 195 PRO B N   1 
ATOM   4778 C CA  . PRO C 1 25  ? -29.028 1.16    7.05    1   48.62  ? 195 PRO B CA  1 
ATOM   4779 C C   . PRO C 1 25  ? -30.51  1.504   7.2     1   48.06  ? 195 PRO B C   1 
ATOM   4780 O O   . PRO C 1 25  ? -31.303 0.925   6.491   1   49.9   ? 195 PRO B O   1 
ATOM   4781 C CB  . PRO C 1 25  ? -28.298 2.218   6.205   1   46.19  ? 195 PRO B CB  1 
ATOM   4782 C CG  . PRO C 1 25  ? -27.607 1.444   5.089   1   50.72  ? 195 PRO B CG  1 
ATOM   4783 C CD  . PRO C 1 25  ? -28.287 0.09    4.968   1   49     ? 195 PRO B CD  1 
ATOM   4784 N N   . LYS C 1 26  ? -30.857 2.443   8.088   1   47.39  ? 196 LYS B N   1 
ATOM   4785 C CA  . LYS C 1 26  ? -32.188 3.03    8.132   1   55.01  ? 196 LYS B CA  1 
ATOM   4786 C C   . LYS C 1 26  ? -32.434 3.857   6.869   1   57.15  ? 196 LYS B C   1 
ATOM   4787 O O   . LYS C 1 26  ? -31.63  4.714   6.537   1   56.05  ? 196 LYS B O   1 
ATOM   4788 C CB  . LYS C 1 26  ? -32.356 3.998   9.304   1   58.2   ? 196 LYS B CB  1 
ATOM   4789 C CG  . LYS C 1 26  ? -32.705 3.399   10.655  1   72.63  ? 196 LYS B CG  1 
ATOM   4790 C CD  . LYS C 1 26  ? -32.916 4.489   11.708  1   85.47  ? 196 LYS B CD  1 
ATOM   4791 C CE  . LYS C 1 26  ? -33.88  5.556   11.258  1   89.26  ? 196 LYS B CE  1 
ATOM   4792 N NZ  . LYS C 1 26  ? -33.591 6.867   11.848  1   92.96  ? 196 LYS B NZ  1 
ATOM   4793 N N   . VAL C 1 27  ? -33.563 3.644   6.197   1   59.27  ? 197 VAL B N   1 
ATOM   4794 C CA  . VAL C 1 27  ? -33.837 4.353   4.912   1   59.47  ? 197 VAL B CA  1 
ATOM   4795 C C   . VAL C 1 27  ? -33.942 5.865   5.16    1   60.71  ? 197 VAL B C   1 
ATOM   4796 O O   . VAL C 1 27  ? -33.379 6.633   4.363   1   66.73  ? 197 VAL B O   1 
ATOM   4797 C CB  . VAL C 1 27  ? -35.093 3.809   4.209   1   62.05  ? 197 VAL B CB  1 
ATOM   4798 C CG1 . VAL C 1 27  ? -35.38  4.543   2.906   1   57.6   ? 197 VAL B CG1 1 
ATOM   4799 C CG2 . VAL C 1 27  ? -34.984 2.312   3.958   1   71.95  ? 197 VAL B CG2 1 
ATOM   4800 N N   . GLY C 1 28  ? -34.617 6.281   6.223   1   60.86  ? 198 GLY B N   1 
ATOM   4801 C CA  . GLY C 1 28  ? -34.811 7.727   6.432   1   69.58  ? 198 GLY B CA  1 
ATOM   4802 C C   . GLY C 1 28  ? -33.927 8.277   7.525   1   72.94  ? 198 GLY B C   1 
ATOM   4803 O O   . GLY C 1 28  ? -34.475 8.841   8.486   1   76.54  ? 198 GLY B O   1 
ATOM   4804 N N   . TYR C 1 29  ? -32.694 8.247   7.494   1   65.21  ? 199 TYR B N   1 
ATOM   4805 C CA  . TYR C 1 29  ? -31.827 8.688   8.615   1   56.3   ? 199 TYR B CA  1 
ATOM   4806 C C   . TYR C 1 29  ? -31.351 10.09   8.372   1   54.5   ? 199 TYR B C   1 
ATOM   4807 O O   . TYR C 1 29  ? -31.01  10.779  9.341   1   54.08  ? 199 TYR B O   1 
ATOM   4808 C CB  . TYR C 1 29  ? -30.684 7.666   8.731   1   49.49  ? 199 TYR B CB  1 
ATOM   4809 C CG  . TYR C 1 29  ? -29.452 7.776   7.842   1   44.27  ? 199 TYR B CG  1 
ATOM   4810 C CD1 . TYR C 1 29  ? -28.568 8.841   7.947   1   44.68  ? 199 TYR B CD1 1 
ATOM   4811 C CD2 . TYR C 1 29  ? -29.138 6.77    6.94    1   44.91  ? 199 TYR B CD2 1 
ATOM   4812 C CE1 . TYR C 1 29  ? -27.45  8.935   7.139   1   45.14  ? 199 TYR B CE1 1 
ATOM   4813 C CE2 . TYR C 1 29  ? -28.013 6.843   6.138   1   43.34  ? 199 TYR B CE2 1 
ATOM   4814 C CZ  . TYR C 1 29  ? -27.164 7.928   6.239   1   45.74  ? 199 TYR B CZ  1 
ATOM   4815 O OH  . TYR C 1 29  ? -26.055 8.011   5.453   1   45.85  ? 199 TYR B OH  1 
ATOM   4816 N N   . MET C 1 30  ? -31.249 10.458  7.024   1   52.36  ? 200 MET B N   1 
ATOM   4817 C CA  . MET C 1 30  ? -30.735 11.828  6.788   1   56.15  ? 200 MET B CA  1 
ATOM   4818 C C   . MET C 1 30  ? -31.723 12.849  7.355   1   61.04  ? 200 MET B C   1 
ATOM   4819 O O   . MET C 1 30  ? -31.27  13.878  7.866   1   67.17  ? 200 MET B O   1 
ATOM   4820 C CB  . MET C 1 30  ? -30.478 12.083  5.301   1   58.64  ? 200 MET B CB  1 
ATOM   4821 C CG  . MET C 1 30  ? -29.419 13.124  5.037   1   59.8   ? 200 MET B CG  1 
ATOM   4822 S SD  . MET C 1 30  ? -27.886 12.78   5.918   1   60.47  ? 200 MET B SD  1 
ATOM   4823 C CE  . MET C 1 30  ? -27.049 11.787  4.678   1   63.5   ? 200 MET B CE  1 
ATOM   4824 N N   . LYS C 1 31  ? -33.017 12.554  7.28    1   63.3   ? 201 LYS B N   1 
ATOM   4825 C CA  . LYS C 1 31  ? -33.986 13.481  7.854   1   65.81  ? 201 LYS B CA  1 
ATOM   4826 C C   . LYS C 1 31  ? -33.717 13.677  9.342   1   62.65  ? 201 LYS B C   1 
ATOM   4827 O O   . LYS C 1 31  ? -33.926 14.757  9.874   1   64.05  ? 201 LYS B O   1 
ATOM   4828 C CB  . LYS C 1 31  ? -35.418 12.986  7.622   1   70.7   ? 201 LYS B CB  1 
ATOM   4829 C CG  . LYS C 1 31  ? -35.725 12.991  6.136   1   82.99  ? 201 LYS B CG  1 
ATOM   4830 C CD  . LYS C 1 31  ? -36.907 12.144  5.677   1   99.82  ? 201 LYS B CD  1 
ATOM   4831 C CE  . LYS C 1 31  ? -37.331 12.563  4.282   1   109.64 ? 201 LYS B CE  1 
ATOM   4832 N NZ  . LYS C 1 31  ? -38.518 11.875  3.768   1   111.58 ? 201 LYS B NZ  1 
ATOM   4833 N N   . LYS C 1 32  ? -33.213 12.633  10      1   64.24  ? 202 LYS B N   1 
ATOM   4834 C CA  . LYS C 1 32  ? -32.998 12.666  11.44   1   66.17  ? 202 LYS B CA  1 
ATOM   4835 C C   . LYS C 1 32  ? -31.605 13.196  11.763  1   63.08  ? 202 LYS B C   1 
ATOM   4836 O O   . LYS C 1 32  ? -31.304 13.37   12.942  1   61.68  ? 202 LYS B O   1 
ATOM   4837 C CB  . LYS C 1 32  ? -33.275 11.298  12.074  1   71.95  ? 202 LYS B CB  1 
ATOM   4838 C CG  . LYS C 1 32  ? -34.755 11.157  12.446  1   87.62  ? 202 LYS B CG  1 
ATOM   4839 C CD  . LYS C 1 32  ? -35.462 9.836   12.152  1   92.15  ? 202 LYS B CD  1 
ATOM   4840 C CE  . LYS C 1 32  ? -36.948 10.063  12.191  1   98.67  ? 202 LYS B CE  1 
ATOM   4841 N NZ  . LYS C 1 32  ? -37.7   8.872   11.796  1   103.7  ? 202 LYS B NZ  1 
ATOM   4842 N N   . GLN C 1 33  ? -30.789 13.457  10.722  1   55.99  ? 203 GLN B N   1 
ATOM   4843 C CA  . GLN C 1 33  ? -29.503 14.114  10.901  1   53.99  ? 203 GLN B CA  1 
ATOM   4844 C C   . GLN C 1 33  ? -29.705 15.625  10.831  1   54.04  ? 203 GLN B C   1 
ATOM   4845 O O   . GLN C 1 33  ? -30.017 16.16   9.769   1   59.02  ? 203 GLN B O   1 
ATOM   4846 C CB  . GLN C 1 33  ? -28.477 13.611  9.882   1   51     ? 203 GLN B CB  1 
ATOM   4847 C CG  . GLN C 1 33  ? -27.988 12.184  10.116  1   47.69  ? 203 GLN B CG  1 
ATOM   4848 C CD  . GLN C 1 33  ? -26.91  12.046  11.175  1   47.88  ? 203 GLN B CD  1 
ATOM   4849 O OE1 . GLN C 1 33  ? -26.34  13.022  11.668  1   48.91  ? 203 GLN B OE1 1 
ATOM   4850 N NE2 . GLN C 1 33  ? -26.593 10.813  11.535  1   46.26  ? 203 GLN B NE2 1 
ATOM   4851 N N   . PRO C 1 34  ? -29.555 16.356  11.958  1   55.23  ? 204 PRO B N   1 
ATOM   4852 C CA  . PRO C 1 34  ? -29.776 17.804  11.977  1   56.69  ? 204 PRO B CA  1 
ATOM   4853 C C   . PRO C 1 34  ? -28.795 18.62   11.149  1   56.09  ? 204 PRO B C   1 
ATOM   4854 O O   . PRO C 1 34  ? -29.183 19.637  10.598  1   59.58  ? 204 PRO B O   1 
ATOM   4855 C CB  . PRO C 1 34  ? -29.749 18.211  13.47   1   55.38  ? 204 PRO B CB  1 
ATOM   4856 C CG  . PRO C 1 34  ? -29.003 17.076  14.141  1   54.8   ? 204 PRO B CG  1 
ATOM   4857 C CD  . PRO C 1 34  ? -29.248 15.831  13.299  1   53.81  ? 204 PRO B CD  1 
ATOM   4858 N N   . ASP C 1 35  ? -27.545 18.159  11.042  1   57.33  ? 205 ASP B N   1 
ATOM   4859 C CA  . ASP C 1 35  ? -26.493 19.02   10.524  1   59     ? 205 ASP B CA  1 
ATOM   4860 C C   . ASP C 1 35  ? -25.927 18.531  9.189   1   60.67  ? 205 ASP B C   1 
ATOM   4861 O O   . ASP C 1 35  ? -25.06  19.183  8.608   1   64.31  ? 205 ASP B O   1 
ATOM   4862 C CB  . ASP C 1 35  ? -25.379 19.181  11.539  1   60.44  ? 205 ASP B CB  1 
ATOM   4863 C CG  . ASP C 1 35  ? -24.567 20.437  11.299  1   65.03  ? 205 ASP B CG  1 
ATOM   4864 O OD1 . ASP C 1 35  ? -25.218 21.498  11.164  1   69.26  ? 205 ASP B OD1 1 
ATOM   4865 O OD2 . ASP C 1 35  ? -23.317 20.332  11.206  1   63.64  ? 205 ASP B OD2 1 
ATOM   4866 N N   . ILE C 1 36  ? -26.389 17.371  8.718   1   58.18  ? 206 ILE B N   1 
ATOM   4867 C CA  . ILE C 1 36  ? -25.904 16.836  7.464   1   56.27  ? 206 ILE B CA  1 
ATOM   4868 C C   . ILE C 1 36  ? -27.076 16.441  6.563   1   57.15  ? 206 ILE B C   1 
ATOM   4869 O O   . ILE C 1 36  ? -28.225 16.31   7.012   1   61.93  ? 206 ILE B O   1 
ATOM   4870 C CB  . ILE C 1 36  ? -24.875 15.713  7.689   1   57.49  ? 206 ILE B CB  1 
ATOM   4871 C CG1 . ILE C 1 36  ? -25.473 14.457  8.223   1   55.04  ? 206 ILE B CG1 1 
ATOM   4872 C CG2 . ILE C 1 36  ? -23.715 16.181  8.573   1   61.18  ? 206 ILE B CG2 1 
ATOM   4873 C CD1 . ILE C 1 36  ? -24.493 13.299  8.202   1   54.89  ? 206 ILE B CD1 1 
ATOM   4874 N N   . THR C 1 37  ? -26.753 16.308  5.268   1   54.52  ? 207 THR B N   1 
ATOM   4875 C CA  . THR C 1 37  ? -27.686 16.258  4.147   1   55.18  ? 207 THR B CA  1 
ATOM   4876 C C   . THR C 1 37  ? -27.19  15.224  3.144   1   54.47  ? 207 THR B C   1 
ATOM   4877 O O   . THR C 1 37  ? -25.997 14.868  3.116   1   52.56  ? 207 THR B O   1 
ATOM   4878 C CB  . THR C 1 37  ? -27.755 17.606  3.417   1   55.6   ? 207 THR B CB  1 
ATOM   4879 O OG1 . THR C 1 37  ? -26.511 17.796  2.741   1   52.94  ? 207 THR B OG1 1 
ATOM   4880 C CG2 . THR C 1 37  ? -28.077 18.788  4.309   1   53.56  ? 207 THR B CG2 1 
ATOM   4881 N N   . ASN C 1 38  ? -28.107 14.788  2.274   1   54.72  ? 208 ASN B N   1 
ATOM   4882 C CA  . ASN C 1 38  ? -27.711 13.829  1.257   1   54.28  ? 208 ASN B CA  1 
ATOM   4883 C C   . ASN C 1 38  ? -26.55  14.403  0.444   1   53.53  ? 208 ASN B C   1 
ATOM   4884 O O   . ASN C 1 38  ? -25.673 13.666  0.01    1   55.37  ? 208 ASN B O   1 
ATOM   4885 C CB  . ASN C 1 38  ? -28.843 13.449  0.314   1   54.77  ? 208 ASN B CB  1 
ATOM   4886 C CG  . ASN C 1 38  ? -30.007 12.812  1.029   1   56.13  ? 208 ASN B CG  1 
ATOM   4887 O OD1 . ASN C 1 38  ? -29.828 11.843  1.773   1   56.44  ? 208 ASN B OD1 1 
ATOM   4888 N ND2 . ASN C 1 38  ? -31.201 13.327  0.78    1   54.93  ? 208 ASN B ND2 1 
ATOM   4889 N N   . SER C 1 39  ? -26.56  15.717  0.229   1   52.9   ? 209 SER B N   1 
ATOM   4890 C CA  . SER C 1 39  ? -25.577 16.345  -0.632  1   53.7   ? 209 SER B CA  1 
ATOM   4891 C C   . SER C 1 39  ? -24.18  16.24   -0.008  1   53.1   ? 209 SER B C   1 
ATOM   4892 O O   . SER C 1 39  ? -23.201 15.955  -0.697  1   52.13  ? 209 SER B O   1 
ATOM   4893 C CB  . SER C 1 39  ? -26.02  17.748  -0.992  1   55.13  ? 209 SER B CB  1 
ATOM   4894 O OG  . SER C 1 39  ? -24.912 18.579  -1.301  1   62.99  ? 209 SER B OG  1 
ATOM   4895 N N   . MET C 1 40  ? -24.099 16.412  1.314   1   52.45  ? 210 MET B N   1 
ATOM   4896 C CA  . MET C 1 40  ? -22.832 16.323  2.019   1   51.66  ? 210 MET B CA  1 
ATOM   4897 C C   . MET C 1 40  ? -22.278 14.908  2.023   1   50.81  ? 210 MET B C   1 
ATOM   4898 O O   . MET C 1 40  ? -21.065 14.731  2.035   1   53.67  ? 210 MET B O   1 
ATOM   4899 C CB  . MET C 1 40  ? -22.999 16.746  3.475   1   52.53  ? 210 MET B CB  1 
ATOM   4900 C CG  . MET C 1 40  ? -23.112 18.238  3.583   1   54.25  ? 210 MET B CG  1 
ATOM   4901 S SD  . MET C 1 40  ? -23.455 18.539  5.316   1   57.34  ? 210 MET B SD  1 
ATOM   4902 C CE  . MET C 1 40  ? -23.956 20.269  5.206   1   55.03  ? 210 MET B CE  1 
ATOM   4903 N N   . ARG C 1 41  ? -23.173 13.92   2.078   1   50.49  ? 211 ARG B N   1 
ATOM   4904 C CA  . ARG C 1 41  ? -22.809 12.514  2.024   1   46.33  ? 211 ARG B CA  1 
ATOM   4905 C C   . ARG C 1 41  ? -22.26  12.187  0.639   1   47.71  ? 211 ARG B C   1 
ATOM   4906 O O   . ARG C 1 41  ? -21.354 11.371  0.51    1   47.98  ? 211 ARG B O   1 
ATOM   4907 C CB  . ARG C 1 41  ? -24.051 11.672  2.344   1   48.01  ? 211 ARG B CB  1 
ATOM   4908 C CG  . ARG C 1 41  ? -23.85  10.167  2.26    1   46.67  ? 211 ARG B CG  1 
ATOM   4909 C CD  . ARG C 1 41  ? -25.184 9.436   2.378   1   47.01  ? 211 ARG B CD  1 
ATOM   4910 N NE  . ARG C 1 41  ? -25.025 8.009   2.067   1   47.15  ? 211 ARG B NE  1 
ATOM   4911 C CZ  . ARG C 1 41  ? -24.732 7.519   0.857   1   46.41  ? 211 ARG B CZ  1 
ATOM   4912 N NH1 . ARG C 1 41  ? -24.746 8.309   -0.207  1   45.74  ? 211 ARG B NH1 1 
ATOM   4913 N NH2 . ARG C 1 41  ? -24.414 6.244   0.713   1   43.57  ? 211 ARG B NH2 1 
ATOM   4914 N N   . ALA C 1 42  ? -22.851 12.791  -0.403  1   47.05  ? 212 ALA B N   1 
ATOM   4915 C CA  . ALA C 1 42  ? -22.443 12.538  -1.771  1   45.02  ? 212 ALA B CA  1 
ATOM   4916 C C   . ALA C 1 42  ? -21.024 13.084  -1.966  1   48.45  ? 212 ALA B C   1 
ATOM   4917 O O   . ALA C 1 42  ? -20.184 12.447  -2.605  1   49.72  ? 212 ALA B O   1 
ATOM   4918 C CB  . ALA C 1 42  ? -23.445 13.191  -2.709  1   43.88  ? 212 ALA B CB  1 
ATOM   4919 N N   . ILE C 1 43  ? -20.738 14.255  -1.378  1   48.24  ? 213 ILE B N   1 
ATOM   4920 C CA  . ILE C 1 43  ? -19.402 14.81   -1.414  1   47.79  ? 213 ILE B CA  1 
ATOM   4921 C C   . ILE C 1 43  ? -18.446 13.818  -0.753  1   48.47  ? 213 ILE B C   1 
ATOM   4922 O O   . ILE C 1 43  ? -17.367 13.553  -1.31   1   51.36  ? 213 ILE B O   1 
ATOM   4923 C CB  . ILE C 1 43  ? -19.368 16.201  -0.758  1   50.34  ? 213 ILE B CB  1 
ATOM   4924 C CG1 . ILE C 1 43  ? -20.212 17.231  -1.569  1   49.77  ? 213 ILE B CG1 1 
ATOM   4925 C CG2 . ILE C 1 43  ? -17.928 16.689  -0.541  1   48.39  ? 213 ILE B CG2 1 
ATOM   4926 C CD1 . ILE C 1 43  ? -20.205 18.651  -1.022  1   47.74  ? 213 ILE B CD1 1 
ATOM   4927 N N   . LEU C 1 44  ? -18.861 13.243  0.392   1   44.48  ? 214 LEU B N   1 
ATOM   4928 C CA  . LEU C 1 44  ? -18.023 12.314  1.144   1   43.37  ? 214 LEU B CA  1 
ATOM   4929 C C   . LEU C 1 44  ? -17.749 11.031  0.354   1   45.72  ? 214 LEU B C   1 
ATOM   4930 O O   . LEU C 1 44  ? -16.599 10.577  0.253   1   44.21  ? 214 LEU B O   1 
ATOM   4931 C CB  . LEU C 1 44  ? -18.657 12.001  2.49    1   41.64  ? 214 LEU B CB  1 
ATOM   4932 C CG  . LEU C 1 44  ? -17.962 10.918  3.316   1   41.77  ? 214 LEU B CG  1 
ATOM   4933 C CD1 . LEU C 1 44  ? -16.619 11.433  3.857   1   42.11  ? 214 LEU B CD1 1 
ATOM   4934 C CD2 . LEU C 1 44  ? -18.855 10.408  4.462   1   38.87  ? 214 LEU B CD2 1 
ATOM   4935 N N   . VAL C 1 45  ? -18.817 10.452  -0.213  1   46.04  ? 215 VAL B N   1 
ATOM   4936 C CA  . VAL C 1 45  ? -18.671 9.201   -0.94   1   46.87  ? 215 VAL B CA  1 
ATOM   4937 C C   . VAL C 1 45  ? -17.792 9.415   -2.177  1   47.98  ? 215 VAL B C   1 
ATOM   4938 O O   . VAL C 1 45  ? -17.017 8.543   -2.574  1   48.56  ? 215 VAL B O   1 
ATOM   4939 C CB  . VAL C 1 45  ? -20.032 8.56    -1.275  1   43.36  ? 215 VAL B CB  1 
ATOM   4940 C CG1 . VAL C 1 45  ? -19.855 7.248   -2.021  1   39.86  ? 215 VAL B CG1 1 
ATOM   4941 C CG2 . VAL C 1 45  ? -20.807 8.302   0.009   1   42.85  ? 215 VAL B CG2 1 
ATOM   4942 N N   . ASP C 1 46  ? -17.933 10.581  -2.795  1   46.26  ? 216 ASP B N   1 
ATOM   4943 C CA  . ASP C 1 46  ? -17.21  10.857  -4.011  1   47.52  ? 216 ASP B CA  1 
ATOM   4944 C C   . ASP C 1 46  ? -15.728 10.962  -3.686  1   47.85  ? 216 ASP B C   1 
ATOM   4945 O O   . ASP C 1 46  ? -14.894 10.529  -4.488  1   48.54  ? 216 ASP B O   1 
ATOM   4946 C CB  . ASP C 1 46  ? -17.668 12.173  -4.612  1   51.31  ? 216 ASP B CB  1 
ATOM   4947 C CG  . ASP C 1 46  ? -17.008 12.511  -5.931  1   53.41  ? 216 ASP B CG  1 
ATOM   4948 O OD1 . ASP C 1 46  ? -17.313 11.819  -6.928  1   57.09  ? 216 ASP B OD1 1 
ATOM   4949 O OD2 . ASP C 1 46  ? -16.159 13.414  -5.932  1   55.4   ? 216 ASP B OD2 1 
ATOM   4950 N N   . TRP C 1 47  ? -15.43  11.581  -2.527  1   47.26  ? 217 TRP B N   1 
ATOM   4951 C CA  . TRP C 1 47  ? -14.074 11.728  -2.016  1   48     ? 217 TRP B CA  1 
ATOM   4952 C C   . TRP C 1 47  ? -13.453 10.354  -1.71   1   49.5   ? 217 TRP B C   1 
ATOM   4953 O O   . TRP C 1 47  ? -12.305 10.075  -2.091  1   49.25  ? 217 TRP B O   1 
ATOM   4954 C CB  . TRP C 1 47  ? -14.076 12.654  -0.79   1   48.77  ? 217 TRP B CB  1 
ATOM   4955 C CG  . TRP C 1 47  ? -12.732 12.747  -0.119  1   47.98  ? 217 TRP B CG  1 
ATOM   4956 C CD1 . TRP C 1 47  ? -11.648 13.439  -0.57   1   50.18  ? 217 TRP B CD1 1 
ATOM   4957 C CD2 . TRP C 1 47  ? -12.312 12.104  1.097   1   44.76  ? 217 TRP B CD2 1 
ATOM   4958 N NE1 . TRP C 1 47  ? -10.58  13.258  0.273   1   49.53  ? 217 TRP B NE1 1 
ATOM   4959 C CE2 . TRP C 1 47  ? -10.964 12.457  1.311   1   47.55  ? 217 TRP B CE2 1 
ATOM   4960 C CE3 . TRP C 1 47  ? -12.933 11.279  2.023   1   45.72  ? 217 TRP B CE3 1 
ATOM   4961 C CZ2 . TRP C 1 47  ? -10.236 12.016  2.409   1   47.12  ? 217 TRP B CZ2 1 
ATOM   4962 C CZ3 . TRP C 1 47  ? -12.212 10.825  3.107   1   44.53  ? 217 TRP B CZ3 1 
ATOM   4963 C CH2 . TRP C 1 47  ? -10.885 11.195  3.299   1   46.24  ? 217 TRP B CH2 1 
ATOM   4964 N N   . LEU C 1 48  ? -14.23  9.482   -1.044  1   46.28  ? 218 LEU B N   1 
ATOM   4965 C CA  . LEU C 1 48  ? -13.797 8.116   -0.804  1   45.59  ? 218 LEU B CA  1 
ATOM   4966 C C   . LEU C 1 48  ? -13.495 7.39    -2.115  1   46.87  ? 218 LEU B C   1 
ATOM   4967 O O   . LEU C 1 48  ? -12.614 6.538   -2.126  1   47.79  ? 218 LEU B O   1 
ATOM   4968 C CB  . LEU C 1 48  ? -14.832 7.347   0.013   1   46.26  ? 218 LEU B CB  1 
ATOM   4969 C CG  . LEU C 1 48  ? -15.037 7.801   1.464   1   44.33  ? 218 LEU B CG  1 
ATOM   4970 C CD1 . LEU C 1 48  ? -16.102 6.943   2.046   1   42.03  ? 218 LEU B CD1 1 
ATOM   4971 C CD2 . LEU C 1 48  ? -13.763 7.71    2.269   1   45.62  ? 218 LEU B CD2 1 
ATOM   4972 N N   . VAL C 1 49  ? -14.236 7.68    -3.199  1   43.9   ? 219 VAL B N   1 
ATOM   4973 C CA  . VAL C 1 49  ? -13.935 7.075   -4.489  1   44.66  ? 219 VAL B CA  1 
ATOM   4974 C C   . VAL C 1 49  ? -12.532 7.509   -4.94   1   47.92  ? 219 VAL B C   1 
ATOM   4975 O O   . VAL C 1 49  ? -11.729 6.701   -5.4    1   45.38  ? 219 VAL B O   1 
ATOM   4976 C CB  . VAL C 1 49  ? -15.008 7.392   -5.545  1   43.74  ? 219 VAL B CB  1 
ATOM   4977 C CG1 . VAL C 1 49  ? -14.553 7.043   -6.942  1   44.43  ? 219 VAL B CG1 1 
ATOM   4978 C CG2 . VAL C 1 49  ? -16.296 6.639   -5.265  1   45.08  ? 219 VAL B CG2 1 
ATOM   4979 N N   . GLU C 1 50  ? -12.229 8.802   -4.798  1   53.5   ? 220 GLU B N   1 
ATOM   4980 C CA  . GLU C 1 50  ? -10.905 9.324   -5.117  1   59.14  ? 220 GLU B CA  1 
ATOM   4981 C C   . GLU C 1 50  ? -9.815  8.644   -4.286  1   57.24  ? 220 GLU B C   1 
ATOM   4982 O O   . GLU C 1 50  ? -8.77   8.287   -4.835  1   57.35  ? 220 GLU B O   1 
ATOM   4983 C CB  . GLU C 1 50  ? -10.826 10.837  -4.919  1   65.58  ? 220 GLU B CB  1 
ATOM   4984 C CG  . GLU C 1 50  ? -10.922 11.622  -6.225  1   74.63  ? 220 GLU B CG  1 
ATOM   4985 C CD  . GLU C 1 50  ? -10.925 13.126  -6.02   1   79.08  ? 220 GLU B CD  1 
ATOM   4986 O OE1 . GLU C 1 50  ? -10.741 13.884  -7.014  1   85.04  ? 220 GLU B OE1 1 
ATOM   4987 O OE2 . GLU C 1 50  ? -11.144 13.514  -4.847  1   73.16  ? 220 GLU B OE2 1 
ATOM   4988 N N   . VAL C 1 51  ? -10.071 8.489   -2.979  1   50.84  ? 221 VAL B N   1 
ATOM   4989 C CA  . VAL C 1 51  ? -9.103  7.875   -2.085  1   48.92  ? 221 VAL B CA  1 
ATOM   4990 C C   . VAL C 1 51  ? -8.85   6.431   -2.505  1   48.37  ? 221 VAL B C   1 
ATOM   4991 O O   . VAL C 1 51  ? -7.704  5.987   -2.459  1   50.92  ? 221 VAL B O   1 
ATOM   4992 C CB  . VAL C 1 51  ? -9.549  7.963   -0.613  1   48.15  ? 221 VAL B CB  1 
ATOM   4993 C CG1 . VAL C 1 51  ? -8.716  7.09    0.312   1   46.77  ? 221 VAL B CG1 1 
ATOM   4994 C CG2 . VAL C 1 51  ? -9.532  9.397   -0.131  1   46.95  ? 221 VAL B CG2 1 
ATOM   4995 N N   . GLY C 1 52  ? -9.913  5.704   -2.877  1   46.4   ? 222 GLY B N   1 
ATOM   4996 C CA  . GLY C 1 52  ? -9.789  4.348   -3.38   1   44.76  ? 222 GLY B CA  1 
ATOM   4997 C C   . GLY C 1 52  ? -8.881  4.31    -4.613  1   51.1   ? 222 GLY B C   1 
ATOM   4998 O O   . GLY C 1 52  ? -8.141  3.34    -4.801  1   54.24  ? 222 GLY B O   1 
ATOM   4999 N N   . GLU C 1 53  ? -8.932  5.363   -5.447  1   52.74  ? 223 GLU B N   1 
ATOM   5000 C CA  . GLU C 1 53  ? -8.122  5.449   -6.655  1   58.38  ? 223 GLU B CA  1 
ATOM   5001 C C   . GLU C 1 53  ? -6.689  5.842   -6.327  1   60.31  ? 223 GLU B C   1 
ATOM   5002 O O   . GLU C 1 53  ? -5.74   5.285   -6.873  1   64.47  ? 223 GLU B O   1 
ATOM   5003 C CB  . GLU C 1 53  ? -8.72   6.461   -7.633  1   64.06  ? 223 GLU B CB  1 
ATOM   5004 C CG  . GLU C 1 53  ? -9.953  5.916   -8.337  1   65.3   ? 223 GLU B CG  1 
ATOM   5005 C CD  . GLU C 1 53  ? -9.62   4.621   -9.061  1   72.93  ? 223 GLU B CD  1 
ATOM   5006 O OE1 . GLU C 1 53  ? -9.9    3.493   -8.554  1   73.8   ? 223 GLU B OE1 1 
ATOM   5007 O OE2 . GLU C 1 53  ? -9.068  4.776   -10.174 1   83.58  ? 223 GLU B OE2 1 
ATOM   5008 N N   . GLU C 1 54  ? -6.542  6.842   -5.459  1   61.99  ? 224 GLU B N   1 
ATOM   5009 C CA  . GLU C 1 54  ? -5.229  7.301   -5.048  1   62.67  ? 224 GLU B CA  1 
ATOM   5010 C C   . GLU C 1 54  ? -4.43   6.112   -4.507  1   62.09  ? 224 GLU B C   1 
ATOM   5011 O O   . GLU C 1 54  ? -3.236  6.035   -4.741  1   64.25  ? 224 GLU B O   1 
ATOM   5012 C CB  . GLU C 1 54  ? -5.376  8.47    -4.072  1   64.8   ? 224 GLU B CB  1 
ATOM   5013 C CG  . GLU C 1 54  ? -4.05   8.984   -3.51   1   75.37  ? 224 GLU B CG  1 
ATOM   5014 C CD  . GLU C 1 54  ? -3.121  9.688   -4.487  1   86.42  ? 224 GLU B CD  1 
ATOM   5015 O OE1 . GLU C 1 54  ? -3.613  9.989   -5.604  1   90.43  ? 224 GLU B OE1 1 
ATOM   5016 O OE2 . GLU C 1 54  ? -1.916  9.908   -4.171  1   88.59  ? 224 GLU B OE2 1 
ATOM   5017 N N   . TYR C 1 55  ? -5.076  5.195   -3.775  1   56.87  ? 225 TYR B N   1 
ATOM   5018 C CA  . TYR C 1 55  ? -4.349  4.16    -3.057  1   54.51  ? 225 TYR B CA  1 
ATOM   5019 C C   . TYR C 1 55  ? -4.532  2.779   -3.676  1   53.49  ? 225 TYR B C   1 
ATOM   5020 O O   . TYR C 1 55  ? -4.046  1.802   -3.111  1   53.71  ? 225 TYR B O   1 
ATOM   5021 C CB  . TYR C 1 55  ? -4.817  4.145   -1.596  1   54.43  ? 225 TYR B CB  1 
ATOM   5022 C CG  . TYR C 1 55  ? -4.201  5.28    -0.807  1   59.65  ? 225 TYR B CG  1 
ATOM   5023 C CD1 . TYR C 1 55  ? -2.86   5.238   -0.432  1   60.1   ? 225 TYR B CD1 1 
ATOM   5024 C CD2 . TYR C 1 55  ? -4.935  6.415   -0.512  1   62.3   ? 225 TYR B CD2 1 
ATOM   5025 C CE1 . TYR C 1 55  ? -2.281  6.285   0.269   1   63.82  ? 225 TYR B CE1 1 
ATOM   5026 C CE2 . TYR C 1 55  ? -4.353  7.469   0.173   1   65.23  ? 225 TYR B CE2 1 
ATOM   5027 C CZ  . TYR C 1 55  ? -3.032  7.407   0.568   1   63.56  ? 225 TYR B CZ  1 
ATOM   5028 O OH  . TYR C 1 55  ? -2.517  8.485   1.224   1   70.69  ? 225 TYR B OH  1 
ATOM   5029 N N   . LYS C 1 56  ? -5.27   2.704   -4.791  1   54.15  ? 226 LYS B N   1 
ATOM   5030 C CA  . LYS C 1 56  ? -5.455  1.473   -5.546  1   54.67  ? 226 LYS B CA  1 
ATOM   5031 C C   . LYS C 1 56  ? -6.151  0.435   -4.667  1   55.41  ? 226 LYS B C   1 
ATOM   5032 O O   . LYS C 1 56  ? -5.754  -0.726  -4.651  1   56.4   ? 226 LYS B O   1 
ATOM   5033 C CB  . LYS C 1 56  ? -4.149  0.899   -6.109  1   60.1   ? 226 LYS B CB  1 
ATOM   5034 C CG  . LYS C 1 56  ? -3.356  1.845   -7.01   1   72.65  ? 226 LYS B CG  1 
ATOM   5035 C CD  . LYS C 1 56  ? -4.106  2.237   -8.282  1   86.36  ? 226 LYS B CD  1 
ATOM   5036 C CE  . LYS C 1 56  ? -3.56   3.474   -8.967  1   93.94  ? 226 LYS B CE  1 
ATOM   5037 N NZ  . LYS C 1 56  ? -2.128  3.38    -9.255  1   87.68  ? 226 LYS B NZ  1 
ATOM   5038 N N   . LEU C 1 57  ? -7.206  0.855   -3.951  1   49.98  ? 227 LEU B N   1 
ATOM   5039 C CA  . LEU C 1 57  ? -7.972  -0.069  -3.142  1   45.85  ? 227 LEU B CA  1 
ATOM   5040 C C   . LEU C 1 57  ? -8.946  -0.809  -4.047  1   47.17  ? 227 LEU B C   1 
ATOM   5041 O O   . LEU C 1 57  ? -9.281  -0.356  -5.136  1   52.78  ? 227 LEU B O   1 
ATOM   5042 C CB  . LEU C 1 57  ? -8.712  0.698   -2.054  1   44.47  ? 227 LEU B CB  1 
ATOM   5043 C CG  . LEU C 1 57  ? -7.851  1.621   -1.186  1   44.94  ? 227 LEU B CG  1 
ATOM   5044 C CD1 . LEU C 1 57  ? -8.686  2.145   -0.052  1   44.28  ? 227 LEU B CD1 1 
ATOM   5045 C CD2 . LEU C 1 57  ? -6.66   0.861   -0.626  1   45.1   ? 227 LEU B CD2 1 
ATOM   5046 N N   . GLN C 1 58  ? -9.404  -1.967  -3.583  1   47.4   ? 228 GLN B N   1 
ATOM   5047 C CA  . GLN C 1 58  ? -10.447 -2.695  -4.277  1   45.03  ? 228 GLN B CA  1 
ATOM   5048 C C   . GLN C 1 58  ? -11.756 -1.898  -4.23   1   44.53  ? 228 GLN B C   1 
ATOM   5049 O O   . GLN C 1 58  ? -12.026 -1.141  -3.294  1   43.94  ? 228 GLN B O   1 
ATOM   5050 C CB  . GLN C 1 58  ? -10.658 -3.986  -3.487  1   43.93  ? 228 GLN B CB  1 
ATOM   5051 C CG  . GLN C 1 58  ? -9.453  -4.904  -3.416  1   47.79  ? 228 GLN B CG  1 
ATOM   5052 C CD  . GLN C 1 58  ? -9.045  -5.428  -4.777  1   53.34  ? 228 GLN B CD  1 
ATOM   5053 O OE1 . GLN C 1 58  ? -9.811  -6.104  -5.469  1   55.25  ? 228 GLN B OE1 1 
ATOM   5054 N NE2 . GLN C 1 58  ? -7.826  -5.094  -5.171  1   53.89  ? 228 GLN B NE2 1 
ATOM   5055 N N   . ASN C 1 59  ? -12.6   -2.122  -5.234  1   45.04  ? 229 ASN B N   1 
ATOM   5056 C CA  . ASN C 1 59  ? -13.945 -1.573  -5.223  1   46.23  ? 229 ASN B CA  1 
ATOM   5057 C C   . ASN C 1 59  ? -14.722 -2.12   -4.03   1   45.84  ? 229 ASN B C   1 
ATOM   5058 O O   . ASN C 1 59  ? -15.576 -1.416  -3.476  1   51.01  ? 229 ASN B O   1 
ATOM   5059 C CB  . ASN C 1 59  ? -14.696 -1.854  -6.516  1   43.9   ? 229 ASN B CB  1 
ATOM   5060 C CG  . ASN C 1 59  ? -14.066 -1.167  -7.705  1   45.41  ? 229 ASN B CG  1 
ATOM   5061 O OD1 . ASN C 1 59  ? -13.212 -0.287  -7.567  1   44.07  ? 229 ASN B OD1 1 
ATOM   5062 N ND2 . ASN C 1 59  ? -14.491 -1.562  -8.892  1   45.95  ? 229 ASN B ND2 1 
ATOM   5063 N N   . GLU C 1 60  ? -14.425 -3.373  -3.656  1   43.93  ? 230 GLU B N   1 
ATOM   5064 C CA  . GLU C 1 60  ? -15.131 -4.03   -2.565  1   43.15  ? 230 GLU B CA  1 
ATOM   5065 C C   . GLU C 1 60  ? -14.944 -3.205  -1.295  1   42.88  ? 230 GLU B C   1 
ATOM   5066 O O   . GLU C 1 60  ? -15.893 -2.998  -0.536  1   43.3   ? 230 GLU B O   1 
ATOM   5067 C CB  . GLU C 1 60  ? -14.68  -5.485  -2.398  1   40.92  ? 230 GLU B CB  1 
ATOM   5068 C CG  . GLU C 1 60  ? -15.309 -6.208  -1.207  1   39.51  ? 230 GLU B CG  1 
ATOM   5069 C CD  . GLU C 1 60  ? -16.828 -6.406  -1.238  1   42.85  ? 230 GLU B CD  1 
ATOM   5070 O OE1 . GLU C 1 60  ? -17.477 -6.2    -2.302  1   40.64  ? 230 GLU B OE1 1 
ATOM   5071 O OE2 . GLU C 1 60  ? -17.377 -6.757  -0.163  1   40.91  ? 230 GLU B OE2 1 
ATOM   5072 N N   . THR C 1 61  ? -13.721 -2.687  -1.121  1   40.11  ? 231 THR B N   1 
ATOM   5073 C CA  . THR C 1 61  ? -13.348 -1.909  0.045   1   41.18  ? 231 THR B CA  1 
ATOM   5074 C C   . THR C 1 61  ? -14.201 -0.632  0.139   1   42.36  ? 231 THR B C   1 
ATOM   5075 O O   . THR C 1 61  ? -14.622 -0.24   1.23    1   39.4   ? 231 THR B O   1 
ATOM   5076 C CB  . THR C 1 61  ? -11.846 -1.608  -0.006  1   41.06  ? 231 THR B CB  1 
ATOM   5077 O OG1 . THR C 1 61  ? -11.104 -2.828  -0.052  1   41.44  ? 231 THR B OG1 1 
ATOM   5078 C CG2 . THR C 1 61  ? -11.405 -0.796  1.2     1   40.07  ? 231 THR B CG2 1 
ATOM   5079 N N   . LEU C 1 62  ? -14.388 0.048   -1      1   42.05  ? 232 LEU B N   1 
ATOM   5080 C CA  . LEU C 1 62  ? -15.194 1.251   -1.079  1   41.47  ? 232 LEU B CA  1 
ATOM   5081 C C   . LEU C 1 62  ? -16.645 0.928   -0.709  1   40.64  ? 232 LEU B C   1 
ATOM   5082 O O   . LEU C 1 62  ? -17.273 1.659   0.062   1   41.12  ? 232 LEU B O   1 
ATOM   5083 C CB  . LEU C 1 62  ? -15.084 1.875   -2.474  1   43.31  ? 232 LEU B CB  1 
ATOM   5084 C CG  . LEU C 1 62  ? -16.176 2.895   -2.835  1   43.77  ? 232 LEU B CG  1 
ATOM   5085 C CD1 . LEU C 1 62  ? -15.956 4.215   -2.103  1   40.76  ? 232 LEU B CD1 1 
ATOM   5086 C CD2 . LEU C 1 62  ? -16.29  3.105   -4.339  1   42.83  ? 232 LEU B CD2 1 
ATOM   5087 N N   . HIS C 1 63  ? -17.193 -0.149  -1.27   1   39.66  ? 233 HIS B N   1 
ATOM   5088 C CA  . HIS C 1 63  ? -18.575 -0.523  -0.949  1   38.03  ? 233 HIS B CA  1 
ATOM   5089 C C   . HIS C 1 63  ? -18.733 -0.855  0.542   1   39.59  ? 233 HIS B C   1 
ATOM   5090 O O   . HIS C 1 63  ? -19.744 -0.5    1.137   1   41.57  ? 233 HIS B O   1 
ATOM   5091 C CB  . HIS C 1 63  ? -19.006 -1.724  -1.787  1   37.74  ? 233 HIS B CB  1 
ATOM   5092 C CG  . HIS C 1 63  ? -19.479 -1.396  -3.162  1   42.42  ? 233 HIS B CG  1 
ATOM   5093 N ND1 . HIS C 1 63  ? -18.619 -1.114  -4.219  1   46.02  ? 233 HIS B ND1 1 
ATOM   5094 C CD2 . HIS C 1 63  ? -20.727 -1.35   -3.65   1   37.45  ? 233 HIS B CD2 1 
ATOM   5095 C CE1 . HIS C 1 63  ? -19.357 -0.868  -5.31   1   43.42  ? 233 HIS B CE1 1 
ATOM   5096 N NE2 . HIS C 1 63  ? -20.629 -1.032  -4.984  1   41.32  ? 233 HIS B NE2 1 
ATOM   5097 N N   . LEU C 1 64  ? -17.762 -1.556  1.16    1   36.17  ? 234 LEU B N   1 
ATOM   5098 C CA  . LEU C 1 64  ? -17.841 -1.825  2.579   1   35.66  ? 234 LEU B CA  1 
ATOM   5099 C C   . LEU C 1 64  ? -17.857 -0.498  3.334   1   39.11  ? 234 LEU B C   1 
ATOM   5100 O O   . LEU C 1 64  ? -18.642 -0.307  4.264   1   38     ? 234 LEU B O   1 
ATOM   5101 C CB  . LEU C 1 64  ? -16.661 -2.693  3.013   1   34.93  ? 234 LEU B CB  1 
ATOM   5102 C CG  . LEU C 1 64  ? -16.697 -4.139  2.518   1   34.07  ? 234 LEU B CG  1 
ATOM   5103 C CD1 . LEU C 1 64  ? -15.333 -4.754  2.742   1   30.68  ? 234 LEU B CD1 1 
ATOM   5104 C CD2 . LEU C 1 64  ? -17.815 -4.953  3.201   1   33.76  ? 234 LEU B CD2 1 
ATOM   5105 N N   . ALA C 1 65  ? -16.958 0.418   2.957   1   37.79  ? 235 ALA B N   1 
ATOM   5106 C CA  . ALA C 1 65  ? -16.86  1.661   3.707   1   37.59  ? 235 ALA B CA  1 
ATOM   5107 C C   . ALA C 1 65  ? -18.213 2.387   3.734   1   38.22  ? 235 ALA B C   1 
ATOM   5108 O O   . ALA C 1 65  ? -18.634 2.941   4.762   1   39.81  ? 235 ALA B O   1 
ATOM   5109 C CB  . ALA C 1 65  ? -15.775 2.532   3.106   1   36.03  ? 235 ALA B CB  1 
ATOM   5110 N N   . VAL C 1 66  ? -18.856 2.479   2.567   1   36.11  ? 236 VAL B N   1 
ATOM   5111 C CA  . VAL C 1 66  ? -20.098 3.223   2.473   1   38.13  ? 236 VAL B CA  1 
ATOM   5112 C C   . VAL C 1 66  ? -21.14  2.535   3.369   1   40.43  ? 236 VAL B C   1 
ATOM   5113 O O   . VAL C 1 66  ? -21.909 3.22    4.047   1   45.14  ? 236 VAL B O   1 
ATOM   5114 C CB  . VAL C 1 66  ? -20.554 3.357   1.003   1   36.74  ? 236 VAL B CB  1 
ATOM   5115 C CG1 . VAL C 1 66  ? -21.936 4.004   0.902   1   36.08  ? 236 VAL B CG1 1 
ATOM   5116 C CG2 . VAL C 1 66  ? -19.528 4.132   0.187   1   34.2   ? 236 VAL B CG2 1 
ATOM   5117 N N   . ASN C 1 67  ? -21.106 1.191   3.445   1   38.12  ? 237 ASN B N   1 
ATOM   5118 C CA  . ASN C 1 67  ? -22.065 0.456   4.261   1   39.47  ? 237 ASN B CA  1 
ATOM   5119 C C   . ASN C 1 67  ? -21.871 0.814   5.719   1   39.99  ? 237 ASN B C   1 
ATOM   5120 O O   . ASN C 1 67  ? -22.858 1.001   6.44    1   39.95  ? 237 ASN B O   1 
ATOM   5121 C CB  . ASN C 1 67  ? -22.015 -1.05   4.005   1   41.49  ? 237 ASN B CB  1 
ATOM   5122 C CG  . ASN C 1 67  ? -22.742 -1.86   5.048   1   43.66  ? 237 ASN B CG  1 
ATOM   5123 O OD1 . ASN C 1 67  ? -22.144 -2.258  6.045   1   49.72  ? 237 ASN B OD1 1 
ATOM   5124 N ND2 . ASN C 1 67  ? -23.999 -2.192  4.814   1   44.98  ? 237 ASN B ND2 1 
ATOM   5125 N N   . TYR C 1 68  ? -20.591 0.882   6.133   1   39.42  ? 238 TYR B N   1 
ATOM   5126 C CA  . TYR C 1 68  ? -20.21  1.239   7.493   1   39.2   ? 238 TYR B CA  1 
ATOM   5127 C C   . TYR C 1 68  ? -20.689 2.646   7.82    1   40.45  ? 238 TYR B C   1 
ATOM   5128 O O   . TYR C 1 68  ? -21.14  2.891   8.944   1   40     ? 238 TYR B O   1 
ATOM   5129 C CB  . TYR C 1 68  ? -18.708 1.113   7.77    1   39.14  ? 238 TYR B CB  1 
ATOM   5130 C CG  . TYR C 1 68  ? -18.084 -0.259  7.522   1   37.68  ? 238 TYR B CG  1 
ATOM   5131 C CD1 . TYR C 1 68  ? -18.851 -1.423  7.377   1   36.63  ? 238 TYR B CD1 1 
ATOM   5132 C CD2 . TYR C 1 68  ? -16.707 -0.386  7.413   1   37.77  ? 238 TYR B CD2 1 
ATOM   5133 C CE1 . TYR C 1 68  ? -18.282 -2.672  7.135   1   35.76  ? 238 TYR B CE1 1 
ATOM   5134 C CE2 . TYR C 1 68  ? -16.13  -1.621  7.143   1   37     ? 238 TYR B CE2 1 
ATOM   5135 C CZ  . TYR C 1 68  ? -16.899 -2.766  7.019   1   37.62  ? 238 TYR B CZ  1 
ATOM   5136 O OH  . TYR C 1 68  ? -16.253 -3.954  6.786   1   37.5   ? 238 TYR B OH  1 
ATOM   5137 N N   . ILE C 1 69  ? -20.55  3.553   6.838   1   40.57  ? 239 ILE B N   1 
ATOM   5138 C CA  . ILE C 1 69  ? -20.849 4.957   7.057   1   41.25  ? 239 ILE B CA  1 
ATOM   5139 C C   . ILE C 1 69  ? -22.353 5.091   7.282   1   42.05  ? 239 ILE B C   1 
ATOM   5140 O O   . ILE C 1 69  ? -22.785 5.702   8.274   1   46.87  ? 239 ILE B O   1 
ATOM   5141 C CB  . ILE C 1 69  ? -20.345 5.849   5.899   1   41.52  ? 239 ILE B CB  1 
ATOM   5142 C CG1 . ILE C 1 69  ? -18.831 5.843   5.777   1   40.37  ? 239 ILE B CG1 1 
ATOM   5143 C CG2 . ILE C 1 69  ? -20.894 7.271   6.033   1   38.45  ? 239 ILE B CG2 1 
ATOM   5144 C CD1 . ILE C 1 69  ? -18.29  6.566   4.553   1   39.07  ? 239 ILE B CD1 1 
ATOM   5145 N N   . ASP C 1 70  ? -23.15  4.592   6.336   1   39.92  ? 240 ASP B N   1 
ATOM   5146 C CA  . ASP C 1 70  ? -24.624 4.791   6.432   1   42.42  ? 240 ASP B CA  1 
ATOM   5147 C C   . ASP C 1 70  ? -25.157 4.125   7.705   1   42.79  ? 240 ASP B C   1 
ATOM   5148 O O   . ASP C 1 70  ? -26.062 4.706   8.342   1   42.28  ? 240 ASP B O   1 
ATOM   5149 C CB  . ASP C 1 70  ? -25.309 4.337   5.154   1   41.06  ? 240 ASP B CB  1 
ATOM   5150 C CG  . ASP C 1 70  ? -24.88  5.093   3.906   1   42.62  ? 240 ASP B CG  1 
ATOM   5151 O OD1 . ASP C 1 70  ? -24.205 6.134   4.057   1   45.64  ? 240 ASP B OD1 1 
ATOM   5152 O OD2 . ASP C 1 70  ? -25.22  4.637   2.796   1   43.72  ? 240 ASP B OD2 1 
ATOM   5153 N N   . ARG C 1 71  ? -24.609 2.961   8.06    1   42.32  ? 241 ARG B N   1 
ATOM   5154 C CA  . ARG C 1 71  ? -25.077 2.232   9.267   1   41.47  ? 241 ARG B CA  1 
ATOM   5155 C C   . ARG C 1 71  ? -24.755 3.066   10.518  1   41.99  ? 241 ARG B C   1 
ATOM   5156 O O   . ARG C 1 71  ? -25.632 3.184   11.394  1   44.46  ? 241 ARG B O   1 
ATOM   5157 C CB  . ARG C 1 71  ? -24.434 0.843   9.331   1   40.64  ? 241 ARG B CB  1 
ATOM   5158 C CG  . ARG C 1 71  ? -25.144 -0.185  8.463   1   42.3   ? 241 ARG B CG  1 
ATOM   5159 C CD  . ARG C 1 71  ? -24.659 -1.593  8.76    1   43.06  ? 241 ARG B CD  1 
ATOM   5160 N NE  . ARG C 1 71  ? -23.2   -1.721  8.682   1   42.86  ? 241 ARG B NE  1 
ATOM   5161 C CZ  . ARG C 1 71  ? -22.525 -2.771  9.13    1   41.73  ? 241 ARG B CZ  1 
ATOM   5162 N NH1 . ARG C 1 71  ? -23.166 -3.873  9.475   1   38.12  ? 241 ARG B NH1 1 
ATOM   5163 N NH2 . ARG C 1 71  ? -21.209 -2.719  9.227   1   38.75  ? 241 ARG B NH2 1 
ATOM   5164 N N   . PHE C 1 72  ? -23.543 3.619   10.594  1   39.53  ? 242 PHE B N   1 
ATOM   5165 C CA  . PHE C 1 72  ? -23.161 4.472   11.752  1   40.23  ? 242 PHE B CA  1 
ATOM   5166 C C   . PHE C 1 72  ? -24.075 5.688   11.798  1   43.26  ? 242 PHE B C   1 
ATOM   5167 O O   . PHE C 1 72  ? -24.516 6.073   12.902  1   44.87  ? 242 PHE B O   1 
ATOM   5168 C CB  . PHE C 1 72  ? -21.69  4.866   11.586  1   36.72  ? 242 PHE B CB  1 
ATOM   5169 C CG  . PHE C 1 72  ? -21.071 5.636   12.745  1   36.22  ? 242 PHE B CG  1 
ATOM   5170 C CD1 . PHE C 1 72  ? -20.45  4.968   13.794  1   36.95  ? 242 PHE B CD1 1 
ATOM   5171 C CD2 . PHE C 1 72  ? -21.094 7.026   12.774  1   36.04  ? 242 PHE B CD2 1 
ATOM   5172 C CE1 . PHE C 1 72  ? -19.879 5.67    14.843  1   38.5   ? 242 PHE B CE1 1 
ATOM   5173 C CE2 . PHE C 1 72  ? -20.521 7.722   13.826  1   37.14  ? 242 PHE B CE2 1 
ATOM   5174 C CZ  . PHE C 1 72  ? -19.916 7.044   14.858  1   37.04  ? 242 PHE B CZ  1 
ATOM   5175 N N   . LEU C 1 73  ? -24.378 6.269   10.635  1   42.8   ? 243 LEU B N   1 
ATOM   5176 C CA  . LEU C 1 73  ? -25.166 7.485   10.592  1   45.07  ? 243 LEU B CA  1 
ATOM   5177 C C   . LEU C 1 73  ? -26.639 7.185   10.876  1   48.44  ? 243 LEU B C   1 
ATOM   5178 O O   . LEU C 1 73  ? -27.412 8.123   11.089  1   53.06  ? 243 LEU B O   1 
ATOM   5179 C CB  . LEU C 1 73  ? -24.985 8.178   9.243   1   42.89  ? 243 LEU B CB  1 
ATOM   5180 C CG  . LEU C 1 73  ? -23.622 8.83    9.003   1   41.72  ? 243 LEU B CG  1 
ATOM   5181 C CD1 . LEU C 1 73  ? -23.629 9.554   7.702   1   39.53  ? 243 LEU B CD1 1 
ATOM   5182 C CD2 . LEU C 1 73  ? -23.121 9.703   10.16   1   41.37  ? 243 LEU B CD2 1 
ATOM   5183 N N   . SER C 1 74  ? -27.001 5.896   10.897  1   46.42  ? 244 SER B N   1 
ATOM   5184 C CA  . SER C 1 74  ? -28.335 5.45    11.28   1   47.72  ? 244 SER B CA  1 
ATOM   5185 C C   . SER C 1 74  ? -28.578 5.56    12.788  1   50.44  ? 244 SER B C   1 
ATOM   5186 O O   . SER C 1 74  ? -29.726 5.753   13.181  1   50.21  ? 244 SER B O   1 
ATOM   5187 C CB  . SER C 1 74  ? -28.588 4.052   10.807  1   45.27  ? 244 SER B CB  1 
ATOM   5188 O OG  . SER C 1 74  ? -28.593 4.037   9.388   1   44.57  ? 244 SER B OG  1 
ATOM   5189 N N   . SER C 1 75  ? -27.526 5.449   13.637  1   49.23  ? 245 SER B N   1 
ATOM   5190 C CA  . SER C 1 75  ? -27.777 5.606   15.07   1   50.22  ? 245 SER B CA  1 
ATOM   5191 C C   . SER C 1 75  ? -27.023 6.773   15.721  1   50.64  ? 245 SER B C   1 
ATOM   5192 O O   . SER C 1 75  ? -27.336 7.114   16.866  1   50.03  ? 245 SER B O   1 
ATOM   5193 C CB  . SER C 1 75  ? -27.61  4.326   15.836  1   49.24  ? 245 SER B CB  1 
ATOM   5194 O OG  . SER C 1 75  ? -26.274 3.885   15.699  1   50.08  ? 245 SER B OG  1 
ATOM   5195 N N   . MET C 1 76  ? -26.071 7.414   15.002  1   50.49  ? 246 MET B N   1 
ATOM   5196 C CA  . MET C 1 76  ? -25.244 8.474   15.597  1   47.76  ? 246 MET B CA  1 
ATOM   5197 C C   . MET C 1 76  ? -25.396 9.776   14.81   1   47.71  ? 246 MET B C   1 
ATOM   5198 O O   . MET C 1 76  ? -25.168 9.782   13.603  1   47.89  ? 246 MET B O   1 
ATOM   5199 C CB  . MET C 1 76  ? -23.758 8.104   15.585  1   43.55  ? 246 MET B CB  1 
ATOM   5200 C CG  . MET C 1 76  ? -23.489 6.74    16.131  1   42.98  ? 246 MET B CG  1 
ATOM   5201 S SD  . MET C 1 76  ? -23.672 6.685   17.914  1   49.33  ? 246 MET B SD  1 
ATOM   5202 C CE  . MET C 1 76  ? -22.387 7.791   18.497  1   46.84  ? 246 MET B CE  1 
ATOM   5203 N N   . SER C 1 77  ? -25.776 10.862  15.498  1   47.09  ? 247 SER B N   1 
ATOM   5204 C CA  . SER C 1 77  ? -25.805 12.177  14.869  1   49     ? 247 SER B CA  1 
ATOM   5205 C C   . SER C 1 77  ? -24.373 12.696  14.765  1   48.03  ? 247 SER B C   1 
ATOM   5206 O O   . SER C 1 77  ? -23.637 12.625  15.757  1   46.83  ? 247 SER B O   1 
ATOM   5207 C CB  . SER C 1 77  ? -26.637 13.206  15.646  1   49.14  ? 247 SER B CB  1 
ATOM   5208 O OG  . SER C 1 77  ? -27.865 12.658  16.06   1   49.36  ? 247 SER B OG  1 
ATOM   5209 N N   . VAL C 1 78  ? -24.037 13.287  13.604  1   47.68  ? 248 VAL B N   1 
ATOM   5210 C CA  . VAL C 1 78  ? -22.683 13.783  13.368  1   47.67  ? 248 VAL B CA  1 
ATOM   5211 C C   . VAL C 1 78  ? -22.73  15.198  12.807  1   49.04  ? 248 VAL B C   1 
ATOM   5212 O O   . VAL C 1 78  ? -23.444 15.432  11.843  1   52.44  ? 248 VAL B O   1 
ATOM   5213 C CB  . VAL C 1 78  ? -21.974 12.828  12.404  1   47.31  ? 248 VAL B CB  1 
ATOM   5214 C CG1 . VAL C 1 78  ? -20.632 13.377  11.954  1   48.62  ? 248 VAL B CG1 1 
ATOM   5215 C CG2 . VAL C 1 78  ? -21.797 11.462  13.054  1   47.52  ? 248 VAL B CG2 1 
ATOM   5216 N N   . LEU C 1 79  ? -21.976 16.131  13.413  1   49.52  ? 249 LEU B N   1 
ATOM   5217 C CA  . LEU C 1 79  ? -21.825 17.483  12.885  1   50.86  ? 249 LEU B CA  1 
ATOM   5218 C C   . LEU C 1 79  ? -21.073 17.436  11.557  1   51.89  ? 249 LEU B C   1 
ATOM   5219 O O   . LEU C 1 79  ? -20.212 16.572  11.356  1   49.64  ? 249 LEU B O   1 
ATOM   5220 C CB  . LEU C 1 79  ? -21.102 18.376  13.893  1   51.85  ? 249 LEU B CB  1 
ATOM   5221 C CG  . LEU C 1 79  ? -21.839 18.668  15.205  1   55.81  ? 249 LEU B CG  1 
ATOM   5222 C CD1 . LEU C 1 79  ? -21.228 19.897  15.839  1   57.78  ? 249 LEU B CD1 1 
ATOM   5223 C CD2 . LEU C 1 79  ? -23.371 18.825  15.092  1   55.75  ? 249 LEU B CD2 1 
ATOM   5224 N N   . ARG C 1 80  ? -21.352 18.402  10.671  1   53.68  ? 250 ARG B N   1 
ATOM   5225 C CA  . ARG C 1 80  ? -20.787 18.349  9.329   1   53.03  ? 250 ARG B CA  1 
ATOM   5226 C C   . ARG C 1 80  ? -19.258 18.311  9.411   1   54.64  ? 250 ARG B C   1 
ATOM   5227 O O   . ARG C 1 80  ? -18.639 17.641  8.582   1   52.71  ? 250 ARG B O   1 
ATOM   5228 C CB  . ARG C 1 80  ? -21.248 19.498  8.435   1   53.72  ? 250 ARG B CB  1 
ATOM   5229 C CG  . ARG C 1 80  ? -20.648 20.814  8.911   1   58.35  ? 250 ARG B CG  1 
ATOM   5230 C CD  . ARG C 1 80  ? -21.267 22.008  8.222   1   60.27  ? 250 ARG B CD  1 
ATOM   5231 N NE  . ARG C 1 80  ? -22.69  22.111  8.574   1   64.06  ? 250 ARG B NE  1 
ATOM   5232 C CZ  . ARG C 1 80  ? -23.546 22.982  8.037   1   65.32  ? 250 ARG B CZ  1 
ATOM   5233 N NH1 . ARG C 1 80  ? -23.192 23.794  7.051   1   64.73  ? 250 ARG B NH1 1 
ATOM   5234 N NH2 . ARG C 1 80  ? -24.777 23.017  8.473   1   64.63  ? 250 ARG B NH2 1 
ATOM   5235 N N   . GLY C 1 81  ? -18.682 18.99   10.427  1   56.55  ? 251 GLY B N   1 
ATOM   5236 C CA  . GLY C 1 81  ? -17.242 19.072  10.66   1   54.53  ? 251 GLY B CA  1 
ATOM   5237 C C   . GLY C 1 81  ? -16.586 17.71   10.924  1   53.61  ? 251 GLY B C   1 
ATOM   5238 O O   . GLY C 1 81  ? -15.366 17.553  10.777  1   51.37  ? 251 GLY B O   1 
ATOM   5239 N N   . LYS C 1 82  ? -17.401 16.715  11.309  1   51.61  ? 252 LYS B N   1 
ATOM   5240 C CA  . LYS C 1 82  ? -16.863 15.431  11.732  1   48.46  ? 252 LYS B CA  1 
ATOM   5241 C C   . LYS C 1 82  ? -17.273 14.335  10.761  1   45.8   ? 252 LYS B C   1 
ATOM   5242 O O   . LYS C 1 82  ? -16.907 13.189  10.937  1   48.22  ? 252 LYS B O   1 
ATOM   5243 C CB  . LYS C 1 82  ? -17.314 15.156  13.168  1   48     ? 252 LYS B CB  1 
ATOM   5244 C CG  . LYS C 1 82  ? -16.701 16.07   14.228  1   48.64  ? 252 LYS B CG  1 
ATOM   5245 C CD  . LYS C 1 82  ? -15.218 15.734  14.431  1   50.93  ? 252 LYS B CD  1 
ATOM   5246 C CE  . LYS C 1 82  ? -14.601 16.283  15.678  1   51.89  ? 252 LYS B CE  1 
ATOM   5247 N NZ  . LYS C 1 82  ? -14.617 17.751  15.623  1   54.25  ? 252 LYS B NZ  1 
ATOM   5248 N N   . LEU C 1 83  ? -18.021 14.681  9.722   1   44.81  ? 253 LEU B N   1 
ATOM   5249 C CA  . LEU C 1 83  ? -18.495 13.669  8.793   1   45.02  ? 253 LEU B CA  1 
ATOM   5250 C C   . LEU C 1 83  ? -17.311 12.968  8.116   1   47.11  ? 253 LEU B C   1 
ATOM   5251 O O   . LEU C 1 83  ? -17.348 11.758  7.886   1   47.19  ? 253 LEU B O   1 
ATOM   5252 C CB  . LEU C 1 83  ? -19.374 14.356  7.748   1   44.91  ? 253 LEU B CB  1 
ATOM   5253 C CG  . LEU C 1 83  ? -19.958 13.444  6.668   1   45.85  ? 253 LEU B CG  1 
ATOM   5254 C CD1 . LEU C 1 83  ? -20.797 12.294  7.267   1   45.26  ? 253 LEU B CD1 1 
ATOM   5255 C CD2 . LEU C 1 83  ? -20.799 14.293  5.745   1   46.84  ? 253 LEU B CD2 1 
ATOM   5256 N N   . GLN C 1 84  ? -16.261 13.741  7.799   1   47.05  ? 254 GLN B N   1 
ATOM   5257 C CA  . GLN C 1 84  ? -15.091 13.22   7.099   1   48.8   ? 254 GLN B CA  1 
ATOM   5258 C C   . GLN C 1 84  ? -14.272 12.313  8.031   1   46.45  ? 254 GLN B C   1 
ATOM   5259 O O   . GLN C 1 84  ? -13.622 11.381  7.579   1   45.79  ? 254 GLN B O   1 
ATOM   5260 C CB  . GLN C 1 84  ? -14.265 14.352  6.469   1   48.56  ? 254 GLN B CB  1 
ATOM   5261 C CG  . GLN C 1 84  ? -13.025 13.835  5.741   1   48.31  ? 254 GLN B CG  1 
ATOM   5262 C CD  . GLN C 1 84  ? -12.195 14.907  5.068   1   49.49  ? 254 GLN B CD  1 
ATOM   5263 O OE1 . GLN C 1 84  ? -11.73  14.715  3.946   1   52.25  ? 254 GLN B OE1 1 
ATOM   5264 N NE2 . GLN C 1 84  ? -11.929 16.011  5.747   1   49.88  ? 254 GLN B NE2 1 
ATOM   5265 N N   . LEU C 1 85  ? -14.309 12.604  9.333   1   44.56  ? 255 LEU B N   1 
ATOM   5266 C CA  . LEU C 1 85  ? -13.667 11.738  10.291  1   44.01  ? 255 LEU B CA  1 
ATOM   5267 C C   . LEU C 1 85  ? -14.338 10.375  10.299  1   41.81  ? 255 LEU B C   1 
ATOM   5268 O O   . LEU C 1 85  ? -13.644 9.375   10.386  1   42.68  ? 255 LEU B O   1 
ATOM   5269 C CB  . LEU C 1 85  ? -13.633 12.377  11.679  1   44.19  ? 255 LEU B CB  1 
ATOM   5270 C CG  . LEU C 1 85  ? -12.951 11.525  12.756  1   44.53  ? 255 LEU B CG  1 
ATOM   5271 C CD1 . LEU C 1 85  ? -11.525 11.13   12.39   1   42.6   ? 255 LEU B CD1 1 
ATOM   5272 C CD2 . LEU C 1 85  ? -12.987 12.304  14.077  1   45.04  ? 255 LEU B CD2 1 
ATOM   5273 N N   . VAL C 1 86  ? -15.672 10.343  10.227  1   42.13  ? 256 VAL B N   1 
ATOM   5274 C CA  . VAL C 1 86  ? -16.414 9.089   10.255  1   40.27  ? 256 VAL B CA  1 
ATOM   5275 C C   . VAL C 1 86  ? -16.024 8.268   9.031   1   40.14  ? 256 VAL B C   1 
ATOM   5276 O O   . VAL C 1 86  ? -15.643 7.099   9.156   1   40.65  ? 256 VAL B O   1 
ATOM   5277 C CB  . VAL C 1 86  ? -17.94  9.304   10.329  1   40.9   ? 256 VAL B CB  1 
ATOM   5278 C CG1 . VAL C 1 86  ? -18.7   8.004   10.143  1   38.86  ? 256 VAL B CG1 1 
ATOM   5279 C CG2 . VAL C 1 86  ? -18.359 9.971   11.625  1   39.58  ? 256 VAL B CG2 1 
ATOM   5280 N N   . GLY C 1 87  ? -16.091 8.914   7.863   1   40.33  ? 257 GLY B N   1 
ATOM   5281 C CA  . GLY C 1 87  ? -15.76  8.289   6.586   1   42.98  ? 257 GLY B CA  1 
ATOM   5282 C C   . GLY C 1 87  ? -14.304 7.824   6.494   1   44.43  ? 257 GLY B C   1 
ATOM   5283 O O   . GLY C 1 87  ? -14.024 6.766   5.927   1   43.74  ? 257 GLY B O   1 
ATOM   5284 N N   . THR C 1 88  ? -13.374 8.626   7.026   1   47.17  ? 258 THR B N   1 
ATOM   5285 C CA  . THR C 1 88  ? -11.972 8.237   7.072   1   49.95  ? 258 THR B CA  1 
ATOM   5286 C C   . THR C 1 88  ? -11.834 6.95    7.876   1   47.31  ? 258 THR B C   1 
ATOM   5287 O O   . THR C 1 88  ? -11.129 6.048   7.454   1   48.53  ? 258 THR B O   1 
ATOM   5288 C CB  . THR C 1 88  ? -11.064 9.316   7.667   1   53.57  ? 258 THR B CB  1 
ATOM   5289 O OG1 . THR C 1 88  ? -11.198 10.495  6.873   1   54.3   ? 258 THR B OG1 1 
ATOM   5290 C CG2 . THR C 1 88  ? -9.61   8.869   7.703   1   54.15  ? 258 THR B CG2 1 
ATOM   5291 N N   . ALA C 1 89  ? -12.498 6.867   9.03    1   45.03  ? 259 ALA B N   1 
ATOM   5292 C CA  . ALA C 1 89  ? -12.336 5.691   9.873   1   44.37  ? 259 ALA B CA  1 
ATOM   5293 C C   . ALA C 1 89  ? -13.045 4.501   9.234   1   43.09  ? 259 ALA B C   1 
ATOM   5294 O O   . ALA C 1 89  ? -12.606 3.36    9.368   1   42.76  ? 259 ALA B O   1 
ATOM   5295 C CB  . ALA C 1 89  ? -12.853 5.97    11.268  1   43.57  ? 259 ALA B CB  1 
ATOM   5296 N N   . ALA C 1 90  ? -14.171 4.767   8.556   1   42.52  ? 260 ALA B N   1 
ATOM   5297 C CA  . ALA C 1 90  ? -14.85  3.715   7.83    1   40.33  ? 260 ALA B CA  1 
ATOM   5298 C C   . ALA C 1 90  ? -13.888 3.08    6.811   1   42.58  ? 260 ALA B C   1 
ATOM   5299 O O   . ALA C 1 90  ? -13.814 1.85    6.694   1   42.95  ? 260 ALA B O   1 
ATOM   5300 C CB  . ALA C 1 90  ? -16.107 4.278   7.194   1   39.13  ? 260 ALA B CB  1 
ATOM   5301 N N   . MET C 1 91  ? -13.15  3.919   6.067   1   41.38  ? 261 MET B N   1 
ATOM   5302 C CA  . MET C 1 91  ? -12.334 3.437   4.96    1   42.08  ? 261 MET B CA  1 
ATOM   5303 C C   . MET C 1 91  ? -11.124 2.652   5.492   1   41.81  ? 261 MET B C   1 
ATOM   5304 O O   . MET C 1 91  ? -10.711 1.652   4.904   1   43.33  ? 261 MET B O   1 
ATOM   5305 C CB  . MET C 1 91  ? -11.899 4.618   4.085   1   44.04  ? 261 MET B CB  1 
ATOM   5306 C CG  . MET C 1 91  ? -11.324 4.248   2.753   1   44.71  ? 261 MET B CG  1 
ATOM   5307 S SD  . MET C 1 91  ? -12.542 3.45    1.694   1   46.92  ? 261 MET B SD  1 
ATOM   5308 C CE  . MET C 1 91  ? -12.211 4.231   0.116   1   47.18  ? 261 MET B CE  1 
ATOM   5309 N N   . LEU C 1 92  ? -10.604 3.072   6.644   1   39.97  ? 262 LEU B N   1 
ATOM   5310 C CA  . LEU C 1 92  ? -9.554  2.375   7.358   1   40.13  ? 262 LEU B CA  1 
ATOM   5311 C C   . LEU C 1 92  ? -10.005 0.968   7.764   1   43.13  ? 262 LEU B C   1 
ATOM   5312 O O   . LEU C 1 92  ? -9.26   0.002   7.559   1   42.88  ? 262 LEU B O   1 
ATOM   5313 C CB  . LEU C 1 92  ? -9.149  3.213   8.569   1   37.91  ? 262 LEU B CB  1 
ATOM   5314 C CG  . LEU C 1 92  ? -8.147  2.553   9.515   1   38.76  ? 262 LEU B CG  1 
ATOM   5315 C CD1 . LEU C 1 92  ? -6.824  2.216   8.794   1   40.24  ? 262 LEU B CD1 1 
ATOM   5316 C CD2 . LEU C 1 92  ? -7.863  3.468   10.663  1   38.19  ? 262 LEU B CD2 1 
ATOM   5317 N N   . LEU C 1 93  ? -11.224 0.854   8.322   1   40.33  ? 263 LEU B N   1 
ATOM   5318 C CA  . LEU C 1 93  ? -11.734 -0.434  8.761   1   40.74  ? 263 LEU B CA  1 
ATOM   5319 C C   . LEU C 1 93  ? -11.957 -1.343  7.552   1   40.61  ? 263 LEU B C   1 
ATOM   5320 O O   . LEU C 1 93  ? -11.588 -2.524  7.553   1   43.85  ? 263 LEU B O   1 
ATOM   5321 C CB  . LEU C 1 93  ? -13.028 -0.24   9.558   1   39.16  ? 263 LEU B CB  1 
ATOM   5322 C CG  . LEU C 1 93  ? -12.813 0.222   11.002  1   41.14  ? 263 LEU B CG  1 
ATOM   5323 C CD1 . LEU C 1 93  ? -14.163 0.636   11.632  1   39.6   ? 263 LEU B CD1 1 
ATOM   5324 C CD2 . LEU C 1 93  ? -12.118 -0.875  11.838  1   38.07  ? 263 LEU B CD2 1 
ATOM   5325 N N   . ALA C 1 94  ? -12.576 -0.774  6.521   1   38.07  ? 264 ALA B N   1 
ATOM   5326 C CA  . ALA C 1 94  ? -12.829 -1.491  5.284   1   36.24  ? 264 ALA B CA  1 
ATOM   5327 C C   . ALA C 1 94  ? -11.513 -2.004  4.688   1   38.69  ? 264 ALA B C   1 
ATOM   5328 O O   . ALA C 1 94  ? -11.453 -3.129  4.216   1   40.4   ? 264 ALA B O   1 
ATOM   5329 C CB  . ALA C 1 94  ? -13.565 -0.578  4.335   1   34.02  ? 264 ALA B CB  1 
ATOM   5330 N N   . SER C 1 95  ? -10.469 -1.166  4.677   1   38.33  ? 265 SER B N   1 
ATOM   5331 C CA  . SER C 1 95  ? -9.153  -1.538  4.186   1   37.92  ? 265 SER B CA  1 
ATOM   5332 C C   . SER C 1 95  ? -8.564  -2.652  5.038   1   37.91  ? 265 SER B C   1 
ATOM   5333 O O   . SER C 1 95  ? -8.084  -3.64   4.491   1   40.49  ? 265 SER B O   1 
ATOM   5334 C CB  . SER C 1 95  ? -8.243  -0.362  4.159   1   39.44  ? 265 SER B CB  1 
ATOM   5335 O OG  . SER C 1 95  ? -8.786  0.576   3.239   1   42.68  ? 265 SER B OG  1 
ATOM   5336 N N   . LYS C 1 96  ? -8.631  -2.539  6.364   1   36.51  ? 266 LYS B N   1 
ATOM   5337 C CA  . LYS C 1 96  ? -8.072  -3.611  7.169   1   39.69  ? 266 LYS B CA  1 
ATOM   5338 C C   . LYS C 1 96  ? -8.826  -4.919  6.936   1   40.78  ? 266 LYS B C   1 
ATOM   5339 O O   . LYS C 1 96  ? -8.253  -5.995  7.063   1   42.12  ? 266 LYS B O   1 
ATOM   5340 C CB  . LYS C 1 96  ? -8.092  -3.252  8.652   1   40.67  ? 266 LYS B CB  1 
ATOM   5341 C CG  . LYS C 1 96  ? -7.065  -2.238  9.113   1   40.01  ? 266 LYS B CG  1 
ATOM   5342 C CD  . LYS C 1 96  ? -7.441  -1.573  10.439  1   39.87  ? 266 LYS B CD  1 
ATOM   5343 C CE  . LYS C 1 96  ? -6.269  -0.905  11.065  1   40.33  ? 266 LYS B CE  1 
ATOM   5344 N NZ  . LYS C 1 96  ? -6.479  -0.47   12.453  1   40.45  ? 266 LYS B NZ  1 
ATOM   5345 N N   . PHE C 1 97  ? -10.112 -4.829  6.6     1   40.29  ? 267 PHE B N   1 
ATOM   5346 C CA  . PHE C 1 97  ? -10.933 -6.018  6.466   1   39.62  ? 267 PHE B CA  1 
ATOM   5347 C C   . PHE C 1 97  ? -10.638 -6.709  5.149   1   39.02  ? 267 PHE B C   1 
ATOM   5348 O O   . PHE C 1 97  ? -10.472 -7.923  5.12    1   39.92  ? 267 PHE B O   1 
ATOM   5349 C CB  . PHE C 1 97  ? -12.421 -5.668  6.498   1   37.1   ? 267 PHE B CB  1 
ATOM   5350 C CG  . PHE C 1 97  ? -13.311 -6.903  6.421   1   39.18  ? 267 PHE B CG  1 
ATOM   5351 C CD1 . PHE C 1 97  ? -13.593 -7.66   7.559   1   38.47  ? 267 PHE B CD1 1 
ATOM   5352 C CD2 . PHE C 1 97  ? -13.865 -7.309  5.203   1   37.15  ? 267 PHE B CD2 1 
ATOM   5353 C CE1 . PHE C 1 97  ? -14.421 -8.786  7.467   1   38.3   ? 267 PHE B CE1 1 
ATOM   5354 C CE2 . PHE C 1 97  ? -14.675 -8.445  5.11    1   35.94  ? 267 PHE B CE2 1 
ATOM   5355 C CZ  . PHE C 1 97  ? -14.95  -9.18   6.239   1   36.5   ? 267 PHE B CZ  1 
ATOM   5356 N N   . GLU C 1 98  ? -10.574 -5.918  4.076   1   38.32  ? 268 GLU B N   1 
ATOM   5357 C CA  . GLU C 1 98  ? -10.651 -6.44   2.719   1   38.23  ? 268 GLU B CA  1 
ATOM   5358 C C   . GLU C 1 98  ? -9.306  -6.391  1.968   1   39.1   ? 268 GLU B C   1 
ATOM   5359 O O   . GLU C 1 98  ? -9.109  -7.223  1.079   1   36.49  ? 268 GLU B O   1 
ATOM   5360 C CB  . GLU C 1 98  ? -11.717 -5.625  1.98    1   37.56  ? 268 GLU B CB  1 
ATOM   5361 C CG  . GLU C 1 98  ? -12.056 -6.175  0.603   1   37.6   ? 268 GLU B CG  1 
ATOM   5362 C CD  . GLU C 1 98  ? -12.682 -7.564  0.643   1   41.63  ? 268 GLU B CD  1 
ATOM   5363 O OE1 . GLU C 1 98  ? -13.242 -7.928  1.705   1   42.01  ? 268 GLU B OE1 1 
ATOM   5364 O OE2 . GLU C 1 98  ? -12.639 -8.284  -0.392  1   41.06  ? 268 GLU B OE2 1 
ATOM   5365 N N   . GLU C 1 99  ? -8.4    -5.444  2.311   1   38.09  ? 269 GLU B N   1 
ATOM   5366 C CA  . GLU C 1 99  ? -7.172  -5.262  1.555   1   40.73  ? 269 GLU B CA  1 
ATOM   5367 C C   . GLU C 1 99  ? -6.077  -6.22   2.02    1   44.47  ? 269 GLU B C   1 
ATOM   5368 O O   . GLU C 1 99  ? -5.891  -6.449  3.21    1   45.02  ? 269 GLU B O   1 
ATOM   5369 C CB  . GLU C 1 99  ? -6.609  -3.854  1.688   1   41.88  ? 269 GLU B CB  1 
ATOM   5370 C CG  . GLU C 1 99  ? -7.476  -2.808  1.001   1   46     ? 269 GLU B CG  1 
ATOM   5371 C CD  . GLU C 1 99  ? -7.624  -2.953  -0.5    1   47.54  ? 269 GLU B CD  1 
ATOM   5372 O OE1 . GLU C 1 99  ? -6.608  -3.343  -1.118  1   55.8   ? 269 GLU B OE1 1 
ATOM   5373 O OE2 . GLU C 1 99  ? -8.706  -2.641  -1.042  1   45.19  ? 269 GLU B OE2 1 
ATOM   5374 N N   . ILE C 1 100 ? -5.329  -6.755  1.043   1   46.35  ? 270 ILE B N   1 
ATOM   5375 C CA  . ILE C 1 100 ? -4.093  -7.47   1.308   1   45.44  ? 270 ILE B CA  1 
ATOM   5376 C C   . ILE C 1 100 ? -3.126  -6.511  1.984   1   48.25  ? 270 ILE B C   1 
ATOM   5377 O O   . ILE C 1 100 ? -2.609  -6.835  3.044   1   52.6   ? 270 ILE B O   1 
ATOM   5378 C CB  . ILE C 1 100 ? -3.494  -8.039  0.01    1   45.58  ? 270 ILE B CB  1 
ATOM   5379 C CG1 . ILE C 1 100 ? -4.463  -8.979  -0.737  1   41.36  ? 270 ILE B CG1 1 
ATOM   5380 C CG2 . ILE C 1 100 ? -2.114  -8.682  0.24    1   42.81  ? 270 ILE B CG2 1 
ATOM   5381 C CD1 . ILE C 1 100 ? -3.83   -9.481  -2.028  1   42.38  ? 270 ILE B CD1 1 
ATOM   5382 N N   . TYR C 1 101 ? -2.907  -5.336  1.382   1   48.79  ? 271 TYR B N   1 
ATOM   5383 C CA  . TYR C 1 101 ? -1.981  -4.351  1.934   1   53.76  ? 271 TYR B CA  1 
ATOM   5384 C C   . TYR C 1 101 ? -2.724  -3.062  2.262   1   54.53  ? 271 TYR B C   1 
ATOM   5385 O O   . TYR C 1 101 ? -2.711  -2.129  1.471   1   60.44  ? 271 TYR B O   1 
ATOM   5386 C CB  . TYR C 1 101 ? -0.807  -4.065  0.984   1   56.69  ? 271 TYR B CB  1 
ATOM   5387 C CG  . TYR C 1 101 ? 0.122   -5.259  0.801   1   60.12  ? 271 TYR B CG  1 
ATOM   5388 C CD1 . TYR C 1 101 ? 0.848   -5.748  1.885   1   60.4   ? 271 TYR B CD1 1 
ATOM   5389 C CD2 . TYR C 1 101 ? 0.246   -5.915  -0.431  1   62.19  ? 271 TYR B CD2 1 
ATOM   5390 C CE1 . TYR C 1 101 ? 1.673   -6.853  1.757   1   64.36  ? 271 TYR B CE1 1 
ATOM   5391 C CE2 . TYR C 1 101 ? 1.092   -7.01   -0.572  1   63.14  ? 271 TYR B CE2 1 
ATOM   5392 C CZ  . TYR C 1 101 ? 1.796   -7.483  0.527   1   66.89  ? 271 TYR B CZ  1 
ATOM   5393 O OH  . TYR C 1 101 ? 2.621   -8.569  0.421   1   80.18  ? 271 TYR B OH  1 
ATOM   5394 N N   . PRO C 1 102 ? -3.415  -2.957  3.421   1   53.33  ? 272 PRO B N   1 
ATOM   5395 C CA  . PRO C 1 102 ? -4.197  -1.748  3.724   1   49.23  ? 272 PRO B CA  1 
ATOM   5396 C C   . PRO C 1 102 ? -3.224  -0.581  3.822   1   47.91  ? 272 PRO B C   1 
ATOM   5397 O O   . PRO C 1 102 ? -2.088  -0.761  4.256   1   49.78  ? 272 PRO B O   1 
ATOM   5398 C CB  . PRO C 1 102 ? -4.814  -2.024  5.089   1   46.42  ? 272 PRO B CB  1 
ATOM   5399 C CG  . PRO C 1 102 ? -3.868  -3.065  5.673   1   50.14  ? 272 PRO B CG  1 
ATOM   5400 C CD  . PRO C 1 102 ? -3.435  -3.95   4.507   1   49.15  ? 272 PRO B CD  1 
ATOM   5401 N N   . PRO C 1 103 ? -3.627  0.661   3.478   1   46.75  ? 273 PRO B N   1 
ATOM   5402 C CA  . PRO C 1 103 ? -2.768  1.813   3.751   1   47.82  ? 273 PRO B CA  1 
ATOM   5403 C C   . PRO C 1 103 ? -2.594  1.999   5.256   1   51.45  ? 273 PRO B C   1 
ATOM   5404 O O   . PRO C 1 103 ? -3.442  1.629   6.056   1   50.6   ? 273 PRO B O   1 
ATOM   5405 C CB  . PRO C 1 103 ? -3.468  2.997   3.094   1   44.51  ? 273 PRO B CB  1 
ATOM   5406 C CG  . PRO C 1 103 ? -4.49   2.363   2.177   1   44.04  ? 273 PRO B CG  1 
ATOM   5407 C CD  . PRO C 1 103 ? -4.884  1.036   2.801   1   44.11  ? 273 PRO B CD  1 
ATOM   5408 N N   . GLU C 1 104 ? -1.463  2.582   5.647   1   56.62  ? 274 GLU B N   1 
ATOM   5409 C CA  . GLU C 1 104 ? -1.216  2.828   7.052   1   58.62  ? 274 GLU B CA  1 
ATOM   5410 C C   . GLU C 1 104 ? -2.108  3.963   7.534   1   55.97  ? 274 GLU B C   1 
ATOM   5411 O O   . GLU C 1 104 ? -2.579  4.8     6.754   1   54.11  ? 274 GLU B O   1 
ATOM   5412 C CB  . GLU C 1 104 ? 0.22    3.302   7.244   1   66     ? 274 GLU B CB  1 
ATOM   5413 C CG  . GLU C 1 104 ? 1.257   2.359   6.648   1   77.97  ? 274 GLU B CG  1 
ATOM   5414 C CD  . GLU C 1 104 ? 2.643   2.929   6.866   1   95.6   ? 274 GLU B CD  1 
ATOM   5415 O OE1 . GLU C 1 104 ? 3.491   2.1     7.255   1   109.22 ? 274 GLU B OE1 1 
ATOM   5416 O OE2 . GLU C 1 104 ? 2.866   4.163   6.694   1   99.2   ? 274 GLU B OE2 1 
ATOM   5417 N N   . VAL C 1 105 ? -2.278  4.004   8.853   1   52.31  ? 275 VAL B N   1 
ATOM   5418 C CA  . VAL C 1 105 ? -3.115  5.008   9.481   1   53.65  ? 275 VAL B CA  1 
ATOM   5419 C C   . VAL C 1 105 ? -2.619  6.41    9.116   1   56.21  ? 275 VAL B C   1 
ATOM   5420 O O   . VAL C 1 105 ? -3.435  7.296   8.821   1   56.87  ? 275 VAL B O   1 
ATOM   5421 C CB  . VAL C 1 105 ? -3.168  4.756   10.998  1   53.78  ? 275 VAL B CB  1 
ATOM   5422 C CG1 . VAL C 1 105 ? -3.815  5.896   11.761  1   51.53  ? 275 VAL B CG1 1 
ATOM   5423 C CG2 . VAL C 1 105 ? -3.863  3.432   11.299  1   51.13  ? 275 VAL B CG2 1 
ATOM   5424 N N   . ALA C 1 106 ? -1.291  6.599   9.107   1   57.13  ? 276 ALA B N   1 
ATOM   5425 C CA  . ALA C 1 106 ? -0.705  7.915   8.883   1   59.67  ? 276 ALA B CA  1 
ATOM   5426 C C   . ALA C 1 106 ? -1.102  8.471   7.509   1   58.84  ? 276 ALA B C   1 
ATOM   5427 O O   . ALA C 1 106 ? -1.215  9.69    7.318   1   61.46  ? 276 ALA B O   1 
ATOM   5428 C CB  . ALA C 1 106 ? 0.794   7.888   9.119   1   60.05  ? 276 ALA B CB  1 
ATOM   5429 N N   . GLU C 1 107 ? -1.333  7.553   6.568   1   56.39  ? 277 GLU B N   1 
ATOM   5430 C CA  . GLU C 1 107 ? -1.763  7.892   5.231   1   56.7   ? 277 GLU B CA  1 
ATOM   5431 C C   . GLU C 1 107 ? -3.24   8.247   5.222   1   56.03  ? 277 GLU B C   1 
ATOM   5432 O O   . GLU C 1 107 ? -3.661  9.096   4.443   1   55.28  ? 277 GLU B O   1 
ATOM   5433 C CB  . GLU C 1 107 ? -1.49   6.724   4.292   1   59.87  ? 277 GLU B CB  1 
ATOM   5434 C CG  . GLU C 1 107 ? -0.014  6.651   3.919   1   68.78  ? 277 GLU B CG  1 
ATOM   5435 C CD  . GLU C 1 107 ? 0.275   5.488   2.991   1   82.67  ? 277 GLU B CD  1 
ATOM   5436 O OE1 . GLU C 1 107 ? 0.944   5.758   1.964   1   93.63  ? 277 GLU B OE1 1 
ATOM   5437 O OE2 . GLU C 1 107 ? -0.169  4.339   3.263   1   78.62  ? 277 GLU B OE2 1 
ATOM   5438 N N   . PHE C 1 108 ? -4.036  7.576   6.061   1   56.74  ? 278 PHE B N   1 
ATOM   5439 C CA  . PHE C 1 108 ? -5.43   7.978   6.244   1   54.08  ? 278 PHE B CA  1 
ATOM   5440 C C   . PHE C 1 108 ? -5.511  9.366   6.889   1   58.51  ? 278 PHE B C   1 
ATOM   5441 O O   . PHE C 1 108 ? -6.433  10.11   6.562   1   61.37  ? 278 PHE B O   1 
ATOM   5442 C CB  . PHE C 1 108 ? -6.245  6.927   7.001   1   49.69  ? 278 PHE B CB  1 
ATOM   5443 C CG  . PHE C 1 108 ? -6.682  5.819   6.063   1   48.61  ? 278 PHE B CG  1 
ATOM   5444 C CD1 . PHE C 1 108 ? -7.699  6.047   5.139   1   47.44  ? 278 PHE B CD1 1 
ATOM   5445 C CD2 . PHE C 1 108 ? -6.046  4.575   6.078   1   47.52  ? 278 PHE B CD2 1 
ATOM   5446 C CE1 . PHE C 1 108 ? -8.069  5.036   4.258   1   48.39  ? 278 PHE B CE1 1 
ATOM   5447 C CE2 . PHE C 1 108 ? -6.424  3.565   5.197   1   45.16  ? 278 PHE B CE2 1 
ATOM   5448 C CZ  . PHE C 1 108 ? -7.431  3.791   4.291   1   46.75  ? 278 PHE B CZ  1 
ATOM   5449 N N   . VAL C 1 109 ? -4.566  9.696   7.799   1   55.09  ? 279 VAL B N   1 
ATOM   5450 C CA  . VAL C 1 109 ? -4.492  11.026  8.375   1   54.74  ? 279 VAL B CA  1 
ATOM   5451 C C   . VAL C 1 109 ? -4.076  12.012  7.28    1   58.48  ? 279 VAL B C   1 
ATOM   5452 O O   . VAL C 1 109 ? -4.488  13.17   7.284   1   60.26  ? 279 VAL B O   1 
ATOM   5453 C CB  . VAL C 1 109 ? -3.511  11.068  9.566   1   55.11  ? 279 VAL B CB  1 
ATOM   5454 C CG1 . VAL C 1 109 ? -3.157  12.492  9.986   1   52.43  ? 279 VAL B CG1 1 
ATOM   5455 C CG2 . VAL C 1 109 ? -3.999  10.254  10.756  1   51.73  ? 279 VAL B CG2 1 
ATOM   5456 N N   . TYR C 1 110 ? -3.233  11.552  6.353   1   60.68  ? 280 TYR B N   1 
ATOM   5457 C CA  . TYR C 1 110 ? -2.657  12.418  5.338   1   63.97  ? 280 TYR B CA  1 
ATOM   5458 C C   . TYR C 1 110 ? -3.703  12.877  4.311   1   66.8   ? 280 TYR B C   1 
ATOM   5459 O O   . TYR C 1 110 ? -3.673  14.033  3.892   1   68.2   ? 280 TYR B O   1 
ATOM   5460 C CB  . TYR C 1 110 ? -1.409  11.785  4.714   1   67.07  ? 280 TYR B CB  1 
ATOM   5461 C CG  . TYR C 1 110 ? -0.823  12.594  3.562   1   74.94  ? 280 TYR B CG  1 
ATOM   5462 C CD1 . TYR C 1 110 ? -0.111  13.772  3.793   1   75.33  ? 280 TYR B CD1 1 
ATOM   5463 C CD2 . TYR C 1 110 ? -1.002  12.18   2.243   1   75.11  ? 280 TYR B CD2 1 
ATOM   5464 C CE1 . TYR C 1 110 ? 0.402   14.514  2.742   1   78.97  ? 280 TYR B CE1 1 
ATOM   5465 C CE2 . TYR C 1 110 ? -0.471  12.901  1.187   1   77.87  ? 280 TYR B CE2 1 
ATOM   5466 C CZ  . TYR C 1 110 ? 0.237   14.067  1.44    1   83.14  ? 280 TYR B CZ  1 
ATOM   5467 O OH  . TYR C 1 110 ? 0.758   14.778  0.393   1   87.75  ? 280 TYR B OH  1 
ATOM   5468 N N   . ILE C 1 111 ? -4.609  11.992  3.857   1   66.93  ? 281 ILE B N   1 
ATOM   5469 C CA  . ILE C 1 111 ? -5.537  12.439  2.822   1   68.42  ? 281 ILE B CA  1 
ATOM   5470 C C   . ILE C 1 111 ? -6.702  13.234  3.405   1   66.96  ? 281 ILE B C   1 
ATOM   5471 O O   . ILE C 1 111 ? -7.534  13.709  2.636   1   65.65  ? 281 ILE B O   1 
ATOM   5472 C CB  . ILE C 1 111 ? -6.01   11.362  1.825   1   66.15  ? 281 ILE B CB  1 
ATOM   5473 C CG1 . ILE C 1 111 ? -6.165  9.999   2.485   1   61.69  ? 281 ILE B CG1 1 
ATOM   5474 C CG2 . ILE C 1 111 ? -5.117  11.315  0.581   1   64.91  ? 281 ILE B CG2 1 
ATOM   5475 C CD1 . ILE C 1 111 ? -7.232  9.968   3.555   1   58.77  ? 281 ILE B CD1 1 
ATOM   5476 N N   . THR C 1 112 ? -6.733  13.413  4.732   1   65.78  ? 282 THR B N   1 
ATOM   5477 C CA  . THR C 1 112 ? -7.682  14.338  5.335   1   68.54  ? 282 THR B CA  1 
ATOM   5478 C C   . THR C 1 112 ? -7.107  15.749  5.403   1   78.11  ? 282 THR B C   1 
ATOM   5479 O O   . THR C 1 112 ? -7.725  16.609  6.031   1   84.53  ? 282 THR B O   1 
ATOM   5480 C CB  . THR C 1 112 ? -8.158  13.892  6.719   1   67.98  ? 282 THR B CB  1 
ATOM   5481 O OG1 . THR C 1 112 ? -7.044  13.888  7.606   1   68.42  ? 282 THR B OG1 1 
ATOM   5482 C CG2 . THR C 1 112 ? -8.881  12.56   6.704   1   58.79  ? 282 THR B CG2 1 
ATOM   5483 N N   . ASP C 1 113 ? -5.934  15.975  4.782   1   88.58  ? 283 ASP B N   1 
ATOM   5484 C CA  . ASP C 1 113 ? -5.301  17.288  4.709   1   92.66  ? 283 ASP B CA  1 
ATOM   5485 C C   . ASP C 1 113 ? -5.051  17.848  6.104   1   91.9   ? 283 ASP B C   1 
ATOM   5486 O O   . ASP C 1 113 ? -5.179  19.051  6.322   1   88.98  ? 283 ASP B O   1 
ATOM   5487 C CB  . ASP C 1 113 ? -6.08   18.279  3.853   1   97.51  ? 283 ASP B CB  1 
ATOM   5488 C CG  . ASP C 1 113 ? -6.048  18.001  2.357   1   104.51 ? 283 ASP B CG  1 
ATOM   5489 O OD1 . ASP C 1 113 ? -5.186  17.199  1.941   1   102.39 ? 283 ASP B OD1 1 
ATOM   5490 O OD2 . ASP C 1 113 ? -6.872  18.606  1.622   1   101.58 ? 283 ASP B OD2 1 
ATOM   5491 N N   . ASP C 1 114 ? -4.718  16.951  7.041   1   98.13  ? 284 ASP B N   1 
ATOM   5492 C CA  . ASP C 1 114 ? -4.441  17.311  8.427   1   104.37 ? 284 ASP B CA  1 
ATOM   5493 C C   . ASP C 1 114 ? -5.63   18.05   9.06    1   92.4   ? 284 ASP B C   1 
ATOM   5494 O O   . ASP C 1 114 ? -5.471  18.851  9.979   1   85.87  ? 284 ASP B O   1 
ATOM   5495 C CB  . ASP C 1 114 ? -3.083  17.993  8.554   1   116    ? 284 ASP B CB  1 
ATOM   5496 C CG  . ASP C 1 114 ? -1.926  17.341  7.802   1   115.72 ? 284 ASP B CG  1 
ATOM   5497 O OD1 . ASP C 1 114 ? -2.01   16.13   7.492   1   108.36 ? 284 ASP B OD1 1 
ATOM   5498 O OD2 . ASP C 1 114 ? -0.944  18.057  7.509   1   112.74 ? 284 ASP B OD2 1 
ATOM   5499 N N   . THR C 1 115 ? -6.851  17.751  8.594   1   86.82  ? 285 THR B N   1 
ATOM   5500 C CA  . THR C 1 115 ? -8.044  18.172  9.315   1   82.48  ? 285 THR B CA  1 
ATOM   5501 C C   . THR C 1 115 ? -8.075  17.465  10.673  1   76.2   ? 285 THR B C   1 
ATOM   5502 O O   . THR C 1 115 ? -8.389  18.078  11.682  1   80.07  ? 285 THR B O   1 
ATOM   5503 C CB  . THR C 1 115 ? -9.331  17.914  8.525   1   79     ? 285 THR B CB  1 
ATOM   5504 O OG1 . THR C 1 115 ? -9.128  18.169  7.145   1   74.65  ? 285 THR B OG1 1 
ATOM   5505 C CG2 . THR C 1 115 ? -10.486 18.782  8.993   1   76.16  ? 285 THR B CG2 1 
ATOM   5506 N N   . TYR C 1 116 ? -7.747  16.169  10.685  1   68.74  ? 286 TYR B N   1 
ATOM   5507 C CA  . TYR C 1 116 ? -7.806  15.358  11.892  1   62.7   ? 286 TYR B CA  1 
ATOM   5508 C C   . TYR C 1 116 ? -6.409  14.908  12.296  1   61.11  ? 286 TYR B C   1 
ATOM   5509 O O   . TYR C 1 116 ? -5.472  15.023  11.513  1   65.15  ? 286 TYR B O   1 
ATOM   5510 C CB  . TYR C 1 116 ? -8.741  14.166  11.674  1   56.49  ? 286 TYR B CB  1 
ATOM   5511 C CG  . TYR C 1 116 ? -10.108 14.601  11.165  1   56.03  ? 286 TYR B CG  1 
ATOM   5512 C CD1 . TYR C 1 116 ? -10.958 15.355  11.974  1   55.47  ? 286 TYR B CD1 1 
ATOM   5513 C CD2 . TYR C 1 116 ? -10.537 14.292  9.875   1   53.21  ? 286 TYR B CD2 1 
ATOM   5514 C CE1 . TYR C 1 116 ? -12.191 15.79   11.519  1   52.28  ? 286 TYR B CE1 1 
ATOM   5515 C CE2 . TYR C 1 116 ? -11.783 14.701  9.424   1   52.76  ? 286 TYR B CE2 1 
ATOM   5516 C CZ  . TYR C 1 116 ? -12.597 15.466  10.241  1   52.18  ? 286 TYR B CZ  1 
ATOM   5517 O OH  . TYR C 1 116 ? -13.837 15.834  9.8     1   53.53  ? 286 TYR B OH  1 
ATOM   5518 N N   . THR C 1 117 ? -6.29   14.407  13.531  1   59.55  ? 287 THR B N   1 
ATOM   5519 C CA  . THR C 1 117 ? -5.062  13.839  14.062  1   59.67  ? 287 THR B CA  1 
ATOM   5520 C C   . THR C 1 117 ? -5.125  12.314  14.04   1   60.23  ? 287 THR B C   1 
ATOM   5521 O O   . THR C 1 117 ? -6.183  11.707  13.914  1   57.54  ? 287 THR B O   1 
ATOM   5522 C CB  . THR C 1 117 ? -4.822  14.302  15.496  1   61.14  ? 287 THR B CB  1 
ATOM   5523 O OG1 . THR C 1 117 ? -5.784  13.663  16.333  1   59.41  ? 287 THR B OG1 1 
ATOM   5524 C CG2 . THR C 1 117 ? -4.838  15.811  15.634  1   60.54  ? 287 THR B CG2 1 
ATOM   5525 N N   . LYS C 1 118 ? -3.965  11.692  14.23   1   64.44  ? 288 LYS B N   1 
ATOM   5526 C CA  . LYS C 1 118 ? -3.881  10.245  14.237  1   61.57  ? 288 LYS B CA  1 
ATOM   5527 C C   . LYS C 1 118 ? -4.752  9.734   15.372  1   58.14  ? 288 LYS B C   1 
ATOM   5528 O O   . LYS C 1 118 ? -5.447  8.74    15.194  1   56.06  ? 288 LYS B O   1 
ATOM   5529 C CB  . LYS C 1 118 ? -2.421  9.815   14.417  1   67.33  ? 288 LYS B CB  1 
ATOM   5530 C CG  . LYS C 1 118 ? -2.124  8.393   14.001  1   71.33  ? 288 LYS B CG  1 
ATOM   5531 C CD  . LYS C 1 118 ? -0.808  7.841   14.536  1   77.84  ? 288 LYS B CD  1 
ATOM   5532 C CE  . LYS C 1 118 ? -0.617  6.397   14.173  1   83.14  ? 288 LYS B CE  1 
ATOM   5533 N NZ  . LYS C 1 118 ? 0.19    5.676   15.164  1   90.71  ? 288 LYS B NZ  1 
ATOM   5534 N N   . LYS C 1 119 ? -4.73   10.44   16.509  1   59.63  ? 289 LYS B N   1 
ATOM   5535 C CA  . LYS C 1 119 ? -5.477  10.033  17.695  1   61.55  ? 289 LYS B CA  1 
ATOM   5536 C C   . LYS C 1 119 ? -6.985  10.101  17.438  1   58.57  ? 289 LYS B C   1 
ATOM   5537 O O   . LYS C 1 119 ? -7.725  9.216   17.849  1   60.59  ? 289 LYS B O   1 
ATOM   5538 C CB  . LYS C 1 119 ? -5.114  10.884  18.916  1   66.82  ? 289 LYS B CB  1 
ATOM   5539 C CG  . LYS C 1 119 ? -5.327  10.159  20.229  1   75.56  ? 289 LYS B CG  1 
ATOM   5540 C CD  . LYS C 1 119 ? -4.68   10.784  21.464  1   88.17  ? 289 LYS B CD  1 
ATOM   5541 C CE  . LYS C 1 119 ? -5.459  11.904  22.131  1   96.55  ? 289 LYS B CE  1 
ATOM   5542 N NZ  . LYS C 1 119 ? -6.724  11.477  22.748  1   90.52  ? 289 LYS B NZ  1 
ATOM   5543 N N   . GLN C 1 120 ? -7.44   11.142  16.745  1   55.16  ? 290 GLN B N   1 
ATOM   5544 C CA  . GLN C 1 120 ? -8.833  11.247  16.357  1   54.49  ? 290 GLN B CA  1 
ATOM   5545 C C   . GLN C 1 120 ? -9.231  10.096  15.43   1   52.39  ? 290 GLN B C   1 
ATOM   5546 O O   . GLN C 1 120 ? -10.292 9.477   15.59   1   51.11  ? 290 GLN B O   1 
ATOM   5547 C CB  . GLN C 1 120 ? -9.103  12.589  15.684  1   57.98  ? 290 GLN B CB  1 
ATOM   5548 C CG  . GLN C 1 120 ? -9.062  13.794  16.621  1   62.93  ? 290 GLN B CG  1 
ATOM   5549 C CD  . GLN C 1 120 ? -9.411  15.078  15.897  1   67.9   ? 290 GLN B CD  1 
ATOM   5550 O OE1 . GLN C 1 120 ? -8.681  15.543  15.011  1   70.94  ? 290 GLN B OE1 1 
ATOM   5551 N NE2 . GLN C 1 120 ? -10.563 15.649  16.228  1   65.81  ? 290 GLN B NE2 1 
ATOM   5552 N N   . VAL C 1 121 ? -8.394  9.813   14.434  1   50.14  ? 291 VAL B N   1 
ATOM   5553 C CA  . VAL C 1 121 ? -8.732  8.756   13.507  1   47.28  ? 291 VAL B CA  1 
ATOM   5554 C C   . VAL C 1 121 ? -8.887  7.437   14.256  1   48.92  ? 291 VAL B C   1 
ATOM   5555 O O   . VAL C 1 121 ? -9.781  6.652   13.961  1   50.78  ? 291 VAL B O   1 
ATOM   5556 C CB  . VAL C 1 121 ? -7.745  8.637   12.34   1   46.72  ? 291 VAL B CB  1 
ATOM   5557 C CG1 . VAL C 1 121 ? -8.007  7.368   11.525  1   44.87  ? 291 VAL B CG1 1 
ATOM   5558 C CG2 . VAL C 1 121 ? -7.86   9.849   11.441  1   46.94  ? 291 VAL B CG2 1 
ATOM   5559 N N   . LEU C 1 122 ? -8.02   7.183   15.23   1   50.48  ? 292 LEU B N   1 
ATOM   5560 C CA  . LEU C 1 122 ? -8.012  5.883   15.893  1   52.16  ? 292 LEU B CA  1 
ATOM   5561 C C   . LEU C 1 122 ? -9.162  5.765   16.887  1   51.8   ? 292 LEU B C   1 
ATOM   5562 O O   . LEU C 1 122 ? -9.681  4.669   17.073  1   52.83  ? 292 LEU B O   1 
ATOM   5563 C CB  . LEU C 1 122 ? -6.658  5.636   16.571  1   52.17  ? 292 LEU B CB  1 
ATOM   5564 C CG  . LEU C 1 122 ? -5.464  5.407   15.631  1   50.4   ? 292 LEU B CG  1 
ATOM   5565 C CD1 . LEU C 1 122 ? -4.232  4.998   16.421  1   48.85  ? 292 LEU B CD1 1 
ATOM   5566 C CD2 . LEU C 1 122 ? -5.849  4.369   14.57   1   46.72  ? 292 LEU B CD2 1 
ATOM   5567 N N   . ARG C 1 123 ? -9.555  6.877   17.497  1   53.6   ? 293 ARG B N   1 
ATOM   5568 C CA  . ARG C 1 123 ? -10.674 6.864   18.469  1   54.42  ? 293 ARG B CA  1 
ATOM   5569 C C   . ARG C 1 123 ? -11.972 6.709   17.677  1   50.71  ? 293 ARG B C   1 
ATOM   5570 O O   . ARG C 1 123 ? -12.865 5.992   18.139  1   50.94  ? 293 ARG B O   1 
ATOM   5571 C CB  . ARG C 1 123 ? -10.585 8.117   19.345  1   60.79  ? 293 ARG B CB  1 
ATOM   5572 C CG  . ARG C 1 123 ? -9.471  8.045   20.377  1   66.33  ? 293 ARG B CG  1 
ATOM   5573 C CD  . ARG C 1 123 ? -9.601  9.137   21.42   1   78.3   ? 293 ARG B CD  1 
ATOM   5574 N NE  . ARG C 1 123 ? -10.629 8.819   22.415  1   93.69  ? 293 ARG B NE  1 
ATOM   5575 C CZ  . ARG C 1 123 ? -10.761 7.643   23.013  1   103.21 ? 293 ARG B CZ  1 
ATOM   5576 N NH1 . ARG C 1 123 ? -11.807 6.881   22.748  1   94.05  ? 293 ARG B NH1 1 
ATOM   5577 N NH2 . ARG C 1 123 ? -9.846  7.236   23.875  1   104.79 ? 293 ARG B NH2 1 
ATOM   5578 N N   . MET C 1 124 ? -12.059 7.361   16.526  1   49.01  ? 294 MET B N   1 
ATOM   5579 C CA  . MET C 1 124 ? -13.211 7.157   15.666  1   49.68  ? 294 MET B CA  1 
ATOM   5580 C C   . MET C 1 124 ? -13.278 5.709   15.197  1   49.23  ? 294 MET B C   1 
ATOM   5581 O O   . MET C 1 124 ? -14.376 5.155   15.076  1   48.83  ? 294 MET B O   1 
ATOM   5582 C CB  . MET C 1 124 ? -13.222 8.069   14.436  1   49.15  ? 294 MET B CB  1 
ATOM   5583 C CG  . MET C 1 124 ? -14.516 7.949   13.64   1   48.9   ? 294 MET B CG  1 
ATOM   5584 S SD  . MET C 1 124 ? -16.056 8.349   14.501  1   48.14  ? 294 MET B SD  1 
ATOM   5585 C CE  . MET C 1 124 ? -15.91  10.131  14.673  1   43.84  ? 294 MET B CE  1 
ATOM   5586 N N   . GLU C 1 125 ? -12.139 5.067   14.957  1   47.81  ? 295 GLU B N   1 
ATOM   5587 C CA  . GLU C 1 125 ? -12.145 3.639   14.547  1   46.78  ? 295 GLU B CA  1 
ATOM   5588 C C   . GLU C 1 125 ? -12.82  2.786   15.631  1   47.68  ? 295 GLU B C   1 
ATOM   5589 O O   . GLU C 1 125 ? -13.66  1.942   15.283  1   43.21  ? 295 GLU B O   1 
ATOM   5590 C CB  . GLU C 1 125 ? -10.738 3.133   14.24   1   47.5   ? 295 GLU B CB  1 
ATOM   5591 C CG  . GLU C 1 125 ? -10.637 1.615   14.137  1   45.89  ? 295 GLU B CG  1 
ATOM   5592 C CD  . GLU C 1 125 ? -9.25   1.123   13.779  1   46.73  ? 295 GLU B CD  1 
ATOM   5593 O OE1 . GLU C 1 125 ? -8.421  0.984   14.695  1   49.85  ? 295 GLU B OE1 1 
ATOM   5594 O OE2 . GLU C 1 125 ? -8.999  0.881   12.586  1   43.68  ? 295 GLU B OE2 1 
ATOM   5595 N N   . HIS C 1 126 ? -12.467 3.018   16.89   1   48.33  ? 296 HIS B N   1 
ATOM   5596 C CA  . HIS C 1 126 ? -13.051 2.247   18.014  1   50.79  ? 296 HIS B CA  1 
ATOM   5597 C C   . HIS C 1 126 ? -14.554 2.505   18.101  1   49.96  ? 296 HIS B C   1 
ATOM   5598 O O   . HIS C 1 126 ? -15.31  1.554   18.324  1   49.39  ? 296 HIS B O   1 
ATOM   5599 C CB  . HIS C 1 126 ? -12.367 2.639   19.322  1   58.45  ? 296 HIS B CB  1 
ATOM   5600 C CG  . HIS C 1 126 ? -11.881 1.517   20.163  1   74.26  ? 296 HIS B CG  1 
ATOM   5601 N ND1 . HIS C 1 126 ? -12.335 1.318   21.447  1   84.97  ? 296 HIS B ND1 1 
ATOM   5602 C CD2 . HIS C 1 126 ? -10.974 0.566   19.935  1   79.07  ? 296 HIS B CD2 1 
ATOM   5603 C CE1 . HIS C 1 126 ? -11.716 0.272   21.967  1   96.74  ? 296 HIS B CE1 1 
ATOM   5604 N NE2 . HIS C 1 126 ? -10.891 -0.205  21.062  1   94.39  ? 296 HIS B NE2 1 
ATOM   5605 N N   . LEU C 1 127 ? -14.966 3.76    17.94   1   46.19  ? 297 LEU B N   1 
ATOM   5606 C CA  . LEU C 1 127 ? -16.4   4.108   18.054  1   45.11  ? 297 LEU B CA  1 
ATOM   5607 C C   . LEU C 1 127 ? -17.156 3.442   16.907  1   44.8   ? 297 LEU B C   1 
ATOM   5608 O O   . LEU C 1 127 ? -18.211 2.855   17.162  1   44.77  ? 297 LEU B O   1 
ATOM   5609 C CB  . LEU C 1 127 ? -16.596 5.621   18.057  1   45.54  ? 297 LEU B CB  1 
ATOM   5610 C CG  . LEU C 1 127 ? -18.029 6.118   18.258  1   43.3   ? 297 LEU B CG  1 
ATOM   5611 C CD1 . LEU C 1 127 ? -18.583 5.608   19.571  1   41.31  ? 297 LEU B CD1 1 
ATOM   5612 C CD2 . LEU C 1 127 ? -18.076 7.632   18.208  1   42.74  ? 297 LEU B CD2 1 
ATOM   5613 N N   . VAL C 1 128 ? -16.615 3.522   15.695  1   43.65  ? 298 VAL B N   1 
ATOM   5614 C CA  . VAL C 1 128 ? -17.281 2.822   14.611  1   42.96  ? 298 VAL B CA  1 
ATOM   5615 C C   . VAL C 1 128 ? -17.396 1.328   14.91   1   44.91  ? 298 VAL B C   1 
ATOM   5616 O O   . VAL C 1 128 ? -18.451 0.745   14.663  1   48.72  ? 298 VAL B O   1 
ATOM   5617 C CB  . VAL C 1 128 ? -16.675 3.056   13.225  1   41.67  ? 298 VAL B CB  1 
ATOM   5618 C CG1 . VAL C 1 128 ? -17.248 2.098   12.199  1   41.84  ? 298 VAL B CG1 1 
ATOM   5619 C CG2 . VAL C 1 128 ? -16.908 4.476   12.768  1   43.18  ? 298 VAL B CG2 1 
ATOM   5620 N N   . LEU C 1 129 ? -16.321 0.699   15.406  1   43.26  ? 299 LEU B N   1 
ATOM   5621 C CA  . LEU C 1 129 ? -16.371 -0.709  15.784  1   42.43  ? 299 LEU B CA  1 
ATOM   5622 C C   . LEU C 1 129 ? -17.425 -0.934  16.87   1   42.94  ? 299 LEU B C   1 
ATOM   5623 O O   . LEU C 1 129 ? -18.114 -1.943  16.862  1   44.4   ? 299 LEU B O   1 
ATOM   5624 C CB  . LEU C 1 129 ? -15.002 -1.253  16.205  1   41.38  ? 299 LEU B CB  1 
ATOM   5625 C CG  . LEU C 1 129 ? -13.943 -1.367  15.094  1   42.09  ? 299 LEU B CG  1 
ATOM   5626 C CD1 . LEU C 1 129 ? -12.539 -1.64   15.672  1   40.97  ? 299 LEU B CD1 1 
ATOM   5627 C CD2 . LEU C 1 129 ? -14.322 -2.481  14.155  1   37.87  ? 299 LEU B CD2 1 
ATOM   5628 N N   . LYS C 1 130 ? -17.538 -0.014  17.824  1   45.31  ? 300 LYS B N   1 
ATOM   5629 C CA  . LYS C 1 130 ? -18.475 -0.165  18.927  1   49.05  ? 300 LYS B CA  1 
ATOM   5630 C C   . LYS C 1 130 ? -19.906 -0.093  18.383  1   48.03  ? 300 LYS B C   1 
ATOM   5631 O O   . LYS C 1 130 ? -20.726 -0.949  18.688  1   47.09  ? 300 LYS B O   1 
ATOM   5632 C CB  . LYS C 1 130 ? -18.17  0.868   20.022  1   56.05  ? 300 LYS B CB  1 
ATOM   5633 C CG  . LYS C 1 130 ? -19.1   0.831   21.26   1   69.48  ? 300 LYS B CG  1 
ATOM   5634 C CD  . LYS C 1 130 ? -19.352 2.106   22.082  1   68.06  ? 300 LYS B CD  1 
ATOM   5635 C CE  . LYS C 1 130 ? -20.732 2.122   22.71   1   63.88  ? 300 LYS B CE  1 
ATOM   5636 N NZ  . LYS C 1 130 ? -21.031 3.279   23.557  1   58.78  ? 300 LYS B NZ  1 
ATOM   5637 N N   . VAL C 1 131 ? -20.181 0.882   17.51   1   45.71  ? 301 VAL B N   1 
ATOM   5638 C CA  . VAL C 1 131 ? -21.531 1.091   17.035  1   45.35  ? 301 VAL B CA  1 
ATOM   5639 C C   . VAL C 1 131 ? -21.964 -0.061  16.131  1   46.1   ? 301 VAL B C   1 
ATOM   5640 O O   . VAL C 1 131 ? -23.12  -0.456  16.159  1   50.37  ? 301 VAL B O   1 
ATOM   5641 C CB  . VAL C 1 131 ? -21.648 2.464   16.345  1   46.36  ? 301 VAL B CB  1 
ATOM   5642 C CG1 . VAL C 1 131 ? -22.891 2.579   15.461  1   42.89  ? 301 VAL B CG1 1 
ATOM   5643 C CG2 . VAL C 1 131 ? -21.571 3.603   17.362  1   44.13  ? 301 VAL B CG2 1 
ATOM   5644 N N   . LEU C 1 132 ? -21.048 -0.618  15.336  1   44.13  ? 302 LEU B N   1 
ATOM   5645 C CA  . LEU C 1 132 ? -21.407 -1.692  14.431  1   41.68  ? 302 LEU B CA  1 
ATOM   5646 C C   . LEU C 1 132 ? -21.323 -3.034  15.155  1   43.15  ? 302 LEU B C   1 
ATOM   5647 O O   . LEU C 1 132 ? -21.613 -4.08   14.571  1   43.81  ? 302 LEU B O   1 
ATOM   5648 C CB  . LEU C 1 132 ? -20.474 -1.653  13.223  1   40.39  ? 302 LEU B CB  1 
ATOM   5649 C CG  . LEU C 1 132 ? -20.521 -0.385  12.365  1   42.95  ? 302 LEU B CG  1 
ATOM   5650 C CD1 . LEU C 1 132 ? -19.53  -0.498  11.209  1   42.98  ? 302 LEU B CD1 1 
ATOM   5651 C CD2 . LEU C 1 132 ? -21.883 -0.061  11.805  1   43.05  ? 302 LEU B CD2 1 
ATOM   5652 N N   . ALA C 1 133 ? -20.789 -3.042  16.373  1   44.26  ? 303 ALA B N   1 
ATOM   5653 C CA  . ALA C 1 133 ? -20.569 -4.309  17.119  1   45.32  ? 303 ALA B CA  1 
ATOM   5654 C C   . ALA C 1 133 ? -19.696 -5.266  16.302  1   43.96  ? 303 ALA B C   1 
ATOM   5655 O O   . ALA C 1 133 ? -19.935 -6.477  16.381  1   42.09  ? 303 ALA B O   1 
ATOM   5656 C CB  . ALA C 1 133 ? -21.882 -4.923  17.532  1   41.86  ? 303 ALA B CB  1 
ATOM   5657 N N   . PHE C 1 134 ? -18.734 -4.731  15.547  1   44.83  ? 304 PHE B N   1 
ATOM   5658 C CA  . PHE C 1 134 ? -17.788 -5.531  14.718  1   46.55  ? 304 PHE B CA  1 
ATOM   5659 C C   . PHE C 1 134 ? -18.516 -6.309  13.612  1   47.74  ? 304 PHE B C   1 
ATOM   5660 O O   . PHE C 1 134 ? -17.925 -7.257  13.107  1   47.12  ? 304 PHE B O   1 
ATOM   5661 C CB  . PHE C 1 134 ? -16.909 -6.465  15.56   1   47.01  ? 304 PHE B CB  1 
ATOM   5662 C CG  . PHE C 1 134 ? -15.791 -5.828  16.368  1   51.11  ? 304 PHE B CG  1 
ATOM   5663 C CD1 . PHE C 1 134 ? -16.03  -5.313  17.634  1   52.72  ? 304 PHE B CD1 1 
ATOM   5664 C CD2 . PHE C 1 134 ? -14.495 -5.779  15.871  1   52.55  ? 304 PHE B CD2 1 
ATOM   5665 C CE1 . PHE C 1 134 ? -15.006 -4.747  18.371  1   55.87  ? 304 PHE B CE1 1 
ATOM   5666 C CE2 . PHE C 1 134 ? -13.476 -5.21   16.613  1   51.52  ? 304 PHE B CE2 1 
ATOM   5667 C CZ  . PHE C 1 134 ? -13.733 -4.7    17.86   1   53.38  ? 304 PHE B CZ  1 
ATOM   5668 N N   . ASP C 1 135 ? -19.729 -5.915  13.231  1   48.08  ? 305 ASP B N   1 
ATOM   5669 C CA  . ASP C 1 135 ? -20.414 -6.589  12.095  1   48.02  ? 305 ASP B CA  1 
ATOM   5670 C C   . ASP C 1 135 ? -19.892 -5.966  10.805  1   45.4   ? 305 ASP B C   1 
ATOM   5671 O O   . ASP C 1 135 ? -20.615 -5.159  10.216  1   45.86  ? 305 ASP B O   1 
ATOM   5672 C CB  . ASP C 1 135 ? -21.922 -6.589  12.259  1   60.13  ? 305 ASP B CB  1 
ATOM   5673 C CG  . ASP C 1 135 ? -22.443 -7.508  13.351  1   70.9   ? 305 ASP B CG  1 
ATOM   5674 O OD1 . ASP C 1 135 ? -21.664 -8.369  13.805  1   67.23  ? 305 ASP B OD1 1 
ATOM   5675 O OD2 . ASP C 1 135 ? -23.624 -7.357  13.723  1   81.22  ? 305 ASP B OD2 1 
ATOM   5676 N N   . LEU C 1 136 ? -18.694 -6.361  10.382  1   40.52  ? 306 LEU B N   1 
ATOM   5677 C CA  . LEU C 1 136 ? -18.037 -5.716  9.222   1   41.29  ? 306 LEU B CA  1 
ATOM   5678 C C   . LEU C 1 136 ? -18.144 -6.562  7.943   1   38.86  ? 306 LEU B C   1 
ATOM   5679 O O   . LEU C 1 136 ? -17.911 -6.017  6.863   1   42.74  ? 306 LEU B O   1 
ATOM   5680 C CB  . LEU C 1 136 ? -16.59  -5.493  9.655   1   45.78  ? 306 LEU B CB  1 
ATOM   5681 C CG  . LEU C 1 136 ? -16.343 -4.442  10.742  1   49.62  ? 306 LEU B CG  1 
ATOM   5682 C CD1 . LEU C 1 136 ? -14.983 -3.812  10.532  1   46.45  ? 306 LEU B CD1 1 
ATOM   5683 C CD2 . LEU C 1 136 ? -17.411 -3.372  10.779  1   46.78  ? 306 LEU B CD2 1 
ATOM   5684 N N   . ALA C 1 137 ? -18.476 -7.84   8.06    1   39.38  ? 307 ALA B N   1 
ATOM   5685 C CA  . ALA C 1 137 ? -18.583 -8.686  6.879   1   40.46  ? 307 ALA B CA  1 
ATOM   5686 C C   . ALA C 1 137 ? -19.961 -8.518  6.224   1   38.1   ? 307 ALA B C   1 
ATOM   5687 O O   . ALA C 1 137 ? -20.752 -9.445  6.143   1   43.1   ? 307 ALA B O   1 
ATOM   5688 C CB  . ALA C 1 137 ? -18.289 -10.132 7.262   1   40.17  ? 307 ALA B CB  1 
ATOM   5689 N N   . ALA C 1 138 ? -20.234 -7.303  5.747   1   38.18  ? 308 ALA B N   1 
ATOM   5690 C CA  . ALA C 1 138 ? -21.49  -6.915  5.14    1   37.7   ? 308 ALA B CA  1 
ATOM   5691 C C   . ALA C 1 138 ? -21.468 -7.321  3.675   1   41.89  ? 308 ALA B C   1 
ATOM   5692 O O   . ALA C 1 138 ? -20.451 -7.174  2.993   1   44.86  ? 308 ALA B O   1 
ATOM   5693 C CB  . ALA C 1 138 ? -21.617 -5.413  5.235   1   34.1   ? 308 ALA B CB  1 
ATOM   5694 N N   . PRO C 1 139 ? -22.604 -7.827  3.154   1   43.56  ? 309 PRO B N   1 
ATOM   5695 C CA  . PRO C 1 139 ? -22.812 -7.983  1.713   1   39.83  ? 309 PRO B CA  1 
ATOM   5696 C C   . PRO C 1 139 ? -22.839 -6.634  1.009   1   39.05  ? 309 PRO B C   1 
ATOM   5697 O O   . PRO C 1 139 ? -23.479 -5.69   1.454   1   44.65  ? 309 PRO B O   1 
ATOM   5698 C CB  . PRO C 1 139 ? -24.22  -8.609  1.628   1   40.01  ? 309 PRO B CB  1 
ATOM   5699 C CG  . PRO C 1 139 ? -24.492 -9.181  2.989   1   39.39  ? 309 PRO B CG  1 
ATOM   5700 C CD  . PRO C 1 139 ? -23.774 -8.252  3.944   1   42.98  ? 309 PRO B CD  1 
ATOM   5701 N N   . THR C 1 140 ? -22.221 -6.588  -0.158  1   37.45  ? 310 THR B N   1 
ATOM   5702 C CA  . THR C 1 140 ? -22.196 -5.396  -0.985  1   37.45  ? 310 THR B CA  1 
ATOM   5703 C C   . THR C 1 140 ? -22.874 -5.696  -2.326  1   37.32  ? 310 THR B C   1 
ATOM   5704 O O   . THR C 1 140 ? -23.056 -6.859  -2.701  1   38.6   ? 310 THR B O   1 
ATOM   5705 C CB  . THR C 1 140 ? -20.722 -5.041  -1.204  1   35.73  ? 310 THR B CB  1 
ATOM   5706 O OG1 . THR C 1 140 ? -20.104 -6.094  -1.955  1   36.43  ? 310 THR B OG1 1 
ATOM   5707 C CG2 . THR C 1 140 ? -19.992 -4.829  0.103   1   32.79  ? 310 THR B CG2 1 
ATOM   5708 N N   . ILE C 1 141 ? -23.183 -4.637  -3.067  1   35.39  ? 311 ILE B N   1 
ATOM   5709 C CA  . ILE C 1 141 ? -23.584 -4.766  -4.455  1   39.12  ? 311 ILE B CA  1 
ATOM   5710 C C   . ILE C 1 141 ? -22.615 -5.684  -5.217  1   42.55  ? 311 ILE B C   1 
ATOM   5711 O O   . ILE C 1 141 ? -23.054 -6.5    -6.047  1   44.72  ? 311 ILE B O   1 
ATOM   5712 C CB  . ILE C 1 141 ? -23.672 -3.361  -5.086  1   38.53  ? 311 ILE B CB  1 
ATOM   5713 C CG1 . ILE C 1 141 ? -24.844 -2.551  -4.523  1   35.42  ? 311 ILE B CG1 1 
ATOM   5714 C CG2 . ILE C 1 141 ? -23.688 -3.415  -6.612  1   36.65  ? 311 ILE B CG2 1 
ATOM   5715 C CD1 . ILE C 1 141 ? -24.663 -1.048  -4.649  1   36.88  ? 311 ILE B CD1 1 
ATOM   5716 N N   . ASN C 1 142 ? -21.303 -5.592  -4.931  1   42.07  ? 312 ASN B N   1 
ATOM   5717 C CA  . ASN C 1 142 ? -20.299 -6.299  -5.74   1   44.38  ? 312 ASN B CA  1 
ATOM   5718 C C   . ASN C 1 142 ? -20.361 -7.807  -5.54   1   39.99  ? 312 ASN B C   1 
ATOM   5719 O O   . ASN C 1 142 ? -20.16  -8.581  -6.484  1   41.55  ? 312 ASN B O   1 
ATOM   5720 C CB  . ASN C 1 142 ? -18.857 -5.818  -5.549  1   46.06  ? 312 ASN B CB  1 
ATOM   5721 C CG  . ASN C 1 142 ? -18.549 -4.59   -6.381  1   54.32  ? 312 ASN B CG  1 
ATOM   5722 O OD1 . ASN C 1 142 ? -17.376 -4.292  -6.609  1   56.2   ? 312 ASN B OD1 1 
ATOM   5723 N ND2 . ASN C 1 142 ? -19.55  -3.861  -6.878  1   58.8   ? 312 ASN B ND2 1 
ATOM   5724 N N   . GLN C 1 143 ? -20.54  -8.218  -4.287  1   39.25  ? 313 GLN B N   1 
ATOM   5725 C CA  . GLN C 1 143 ? -20.589 -9.639  -3.988  1   41.47  ? 313 GLN B CA  1 
ATOM   5726 C C   . GLN C 1 143 ? -21.748 -10.277 -4.749  1   40.57  ? 313 GLN B C   1 
ATOM   5727 O O   . GLN C 1 143 ? -21.654 -11.446 -5.123  1   43.76  ? 313 GLN B O   1 
ATOM   5728 C CB  . GLN C 1 143 ? -20.756 -9.876  -2.485  1   42.91  ? 313 GLN B CB  1 
ATOM   5729 C CG  . GLN C 1 143 ? -19.465 -9.741  -1.681  1   39.79  ? 313 GLN B CG  1 
ATOM   5730 C CD  . GLN C 1 143 ? -19.727 -9.736  -0.187  1   39.07  ? 313 GLN B CD  1 
ATOM   5731 O OE1 . GLN C 1 143 ? -20.198 -10.721 0.389   1   39.13  ? 313 GLN B OE1 1 
ATOM   5732 N NE2 . GLN C 1 143 ? -19.417 -8.627  0.466   1   37.65  ? 313 GLN B NE2 1 
ATOM   5733 N N   . PHE C 1 144 ? -22.842 -9.515  -4.961  1   37.81  ? 314 PHE B N   1 
ATOM   5734 C CA  . PHE C 1 144 ? -23.972 -10.015 -5.723  1   35.4   ? 314 PHE B CA  1 
ATOM   5735 C C   . PHE C 1 144 ? -23.667 -9.967  -7.212  1   36.19  ? 314 PHE B C   1 
ATOM   5736 O O   . PHE C 1 144 ? -23.898 -10.96  -7.918  1   38.39  ? 314 PHE B O   1 
ATOM   5737 C CB  . PHE C 1 144 ? -25.239 -9.251  -5.359  1   36     ? 314 PHE B CB  1 
ATOM   5738 C CG  . PHE C 1 144 ? -25.845 -9.704  -4.053  1   35.59  ? 314 PHE B CG  1 
ATOM   5739 C CD1 . PHE C 1 144 ? -26.449 -10.961 -3.968  1   37.66  ? 314 PHE B CD1 1 
ATOM   5740 C CD2 . PHE C 1 144 ? -25.809 -8.882  -2.927  1   35.09  ? 314 PHE B CD2 1 
ATOM   5741 C CE1 . PHE C 1 144 ? -27.012 -11.391 -2.769  1   36.21  ? 314 PHE B CE1 1 
ATOM   5742 C CE2 . PHE C 1 144 ? -26.39  -9.315  -1.728  1   35.93  ? 314 PHE B CE2 1 
ATOM   5743 C CZ  . PHE C 1 144 ? -26.99  -10.561 -1.654  1   35.41  ? 314 PHE B CZ  1 
ATOM   5744 N N   . LEU C 1 145 ? -23.129 -8.836  -7.682  1   37.26  ? 315 LEU B N   1 
ATOM   5745 C CA  . LEU C 1 145 ? -22.771 -8.683  -9.099  1   39.21  ? 315 LEU B CA  1 
ATOM   5746 C C   . LEU C 1 145 ? -21.905 -9.835  -9.628  1   41.14  ? 315 LEU B C   1 
ATOM   5747 O O   . LEU C 1 145 ? -22.204 -10.417 -10.68  1   40.85  ? 315 LEU B O   1 
ATOM   5748 C CB  . LEU C 1 145 ? -22.087 -7.338  -9.33   1   37.56  ? 315 LEU B CB  1 
ATOM   5749 C CG  . LEU C 1 145 ? -23.026 -6.15   -9.573  1   38.36  ? 315 LEU B CG  1 
ATOM   5750 C CD1 . LEU C 1 145 ? -22.192 -4.908  -9.751  1   37.82  ? 315 LEU B CD1 1 
ATOM   5751 C CD2 . LEU C 1 145 ? -23.887 -6.38   -10.795 1   37.93  ? 315 LEU B CD2 1 
ATOM   5752 N N   . THR C 1 146 ? -20.822 -10.143 -8.892  1   38.51  ? 316 THR B N   1 
ATOM   5753 C CA  . THR C 1 146 ? -19.854 -11.107 -9.365  1   37.76  ? 316 THR B CA  1 
ATOM   5754 C C   . THR C 1 146 ? -20.553 -12.451 -9.526  1   37.69  ? 316 THR B C   1 
ATOM   5755 O O   . THR C 1 146 ? -20.254 -13.177 -10.473 1   40.17  ? 316 THR B O   1 
ATOM   5756 C CB  . THR C 1 146 ? -18.591 -11.2   -8.495  1   36.88  ? 316 THR B CB  1 
ATOM   5757 O OG1 . THR C 1 146 ? -18.987 -11.546 -7.169  1   39.96  ? 316 THR B OG1 1 
ATOM   5758 C CG2 . THR C 1 146 ? -17.762 -9.929  -8.469  1   33.77  ? 316 THR B CG2 1 
ATOM   5759 N N   . GLN C 1 147 ? -21.486 -12.784 -8.631  1   37.18  ? 317 GLN B N   1 
ATOM   5760 C CA  . GLN C 1 147 ? -22.252 -14.015 -8.833  1   39.62  ? 317 GLN B CA  1 
ATOM   5761 C C   . GLN C 1 147 ? -23.173 -13.934 -10.057 1   40.68  ? 317 GLN B C   1 
ATOM   5762 O O   . GLN C 1 147 ? -23.297 -14.895 -10.813 1   44.87  ? 317 GLN B O   1 
ATOM   5763 C CB  . GLN C 1 147 ? -23.083 -14.386 -7.611  1   38.78  ? 317 GLN B CB  1 
ATOM   5764 C CG  . GLN C 1 147 ? -22.215 -14.749 -6.43   1   37.83  ? 317 GLN B CG  1 
ATOM   5765 C CD  . GLN C 1 147 ? -23.038 -15.16  -5.243  1   41.67  ? 317 GLN B CD  1 
ATOM   5766 O OE1 . GLN C 1 147 ? -22.698 -14.788 -4.114  1   45.04  ? 317 GLN B OE1 1 
ATOM   5767 N NE2 . GLN C 1 147 ? -24.101 -15.931 -5.475  1   38.37  ? 317 GLN B NE2 1 
ATOM   5768 N N   . TYR C 1 148 ? -23.861 -12.803 -10.233 1   40.67  ? 318 TYR B N   1 
ATOM   5769 C CA  . TYR C 1 148 ? -24.769 -12.665 -11.367 1   41.35  ? 318 TYR B CA  1 
ATOM   5770 C C   . TYR C 1 148 ? -23.976 -12.804 -12.666 1   41.79  ? 318 TYR B C   1 
ATOM   5771 O O   . TYR C 1 148 ? -24.505 -13.302 -13.668 1   40.67  ? 318 TYR B O   1 
ATOM   5772 C CB  . TYR C 1 148 ? -25.483 -11.302 -11.338 1   39.24  ? 318 TYR B CB  1 
ATOM   5773 C CG  . TYR C 1 148 ? -26.403 -11.014 -10.153 1   39.78  ? 318 TYR B CG  1 
ATOM   5774 C CD1 . TYR C 1 148 ? -26.768 -12.006 -9.246  1   38.2   ? 318 TYR B CD1 1 
ATOM   5775 C CD2 . TYR C 1 148 ? -26.907 -9.738  -9.938  1   39.44  ? 318 TYR B CD2 1 
ATOM   5776 C CE1 . TYR C 1 148 ? -27.619 -11.735 -8.19   1   37.98  ? 318 TYR B CE1 1 
ATOM   5777 C CE2 . TYR C 1 148 ? -27.747 -9.46   -8.877  1   38.78  ? 318 TYR B CE2 1 
ATOM   5778 C CZ  . TYR C 1 148 ? -28.129 -10.463 -8.003  1   39.26  ? 318 TYR B CZ  1 
ATOM   5779 O OH  . TYR C 1 148 ? -28.987 -10.204 -6.94   1   37.69  ? 318 TYR B OH  1 
ATOM   5780 N N   . PHE C 1 149 ? -22.715 -12.336 -12.639 1   41.32  ? 319 PHE B N   1 
ATOM   5781 C CA  . PHE C 1 149 ? -21.813 -12.376 -13.792 1   45.81  ? 319 PHE B CA  1 
ATOM   5782 C C   . PHE C 1 149 ? -21.627 -13.801 -14.326 1   43.41  ? 319 PHE B C   1 
ATOM   5783 O O   . PHE C 1 149 ? -21.535 -14.001 -15.524 1   44.05  ? 319 PHE B O   1 
ATOM   5784 C CB  . PHE C 1 149 ? -20.434 -11.791 -13.467 1   41.87  ? 319 PHE B CB  1 
ATOM   5785 C CG  . PHE C 1 149 ? -20.39  -10.283 -13.315 1   41.23  ? 319 PHE B CG  1 
ATOM   5786 C CD1 . PHE C 1 149 ? -21.474 -9.488  -13.696 1   41.8   ? 319 PHE B CD1 1 
ATOM   5787 C CD2 . PHE C 1 149 ? -19.247 -9.675  -12.8   1   38.59  ? 319 PHE B CD2 1 
ATOM   5788 C CE1 . PHE C 1 149 ? -21.419 -8.104  -13.566 1   40.73  ? 319 PHE B CE1 1 
ATOM   5789 C CE2 . PHE C 1 149 ? -19.181 -8.295  -12.686 1   38.87  ? 319 PHE B CE2 1 
ATOM   5790 C CZ  . PHE C 1 149 ? -20.263 -7.514  -13.065 1   43.08  ? 319 PHE B CZ  1 
ATOM   5791 N N   . LEU C 1 150 ? -21.629 -14.799 -13.447 1   42.56  ? 320 LEU B N   1 
ATOM   5792 C CA  . LEU C 1 150 ? -21.51  -16.178 -13.892 1   45.38  ? 320 LEU B CA  1 
ATOM   5793 C C   . LEU C 1 150 ? -22.7   -16.617 -14.754 1   47.78  ? 320 LEU B C   1 
ATOM   5794 O O   . LEU C 1 150 ? -22.658 -17.719 -15.29  1   49.1   ? 320 LEU B O   1 
ATOM   5795 C CB  . LEU C 1 150 ? -21.319 -17.072 -12.666 1   43.66  ? 320 LEU B CB  1 
ATOM   5796 C CG  . LEU C 1 150 ? -20.094 -16.74  -11.811 1   45.56  ? 320 LEU B CG  1 
ATOM   5797 C CD1 . LEU C 1 150 ? -20.114 -17.475 -10.445 1   41.04  ? 320 LEU B CD1 1 
ATOM   5798 C CD2 . LEU C 1 150 ? -18.78  -16.966 -12.63  1   42.45  ? 320 LEU B CD2 1 
ATOM   5799 N N   . HIS C 1 151 ? -23.727 -15.791 -14.895 1   48.32  ? 321 HIS B N   1 
ATOM   5800 C CA  . HIS C 1 151 ? -24.926 -16.234 -15.651 1   50.03  ? 321 HIS B CA  1 
ATOM   5801 C C   . HIS C 1 151 ? -24.878 -15.635 -17.062 1   54.99  ? 321 HIS B C   1 
ATOM   5802 O O   . HIS C 1 151 ? -25.815 -15.841 -17.842 1   58.7   ? 321 HIS B O   1 
ATOM   5803 C CB  . HIS C 1 151 ? -26.202 -15.909 -14.868 1   47.72  ? 321 HIS B CB  1 
ATOM   5804 C CG  . HIS C 1 151 ? -26.416 -16.724 -13.641 1   46.89  ? 321 HIS B CG  1 
ATOM   5805 N ND1 . HIS C 1 151 ? -27.461 -17.611 -13.526 1   47.63  ? 321 HIS B ND1 1 
ATOM   5806 C CD2 . HIS C 1 151 ? -25.757 -16.778 -12.482 1   45.98  ? 321 HIS B CD2 1 
ATOM   5807 C CE1 . HIS C 1 151 ? -27.416 -18.185 -12.335 1   46.63  ? 321 HIS B CE1 1 
ATOM   5808 N NE2 . HIS C 1 151 ? -26.388 -17.694 -11.686 1   42.88  ? 321 HIS B NE2 1 
ATOM   5809 N N   . GLN C 1 152 ? -23.793 -14.939 -17.389 1   64.04  ? 322 GLN B N   1 
ATOM   5810 C CA  . GLN C 1 152 ? -23.631 -14.326 -18.728 1   64.18  ? 322 GLN B CA  1 
ATOM   5811 C C   . GLN C 1 152 ? -23.29  -15.402 -19.756 1   71.56  ? 322 GLN B C   1 
ATOM   5812 O O   . GLN C 1 152 ? -22.526 -16.321 -19.423 1   65.07  ? 322 GLN B O   1 
ATOM   5813 C CB  . GLN C 1 152 ? -22.456 -13.362 -18.823 1   64.2   ? 322 GLN B CB  1 
ATOM   5814 C CG  . GLN C 1 152 ? -22.605 -12.052 -18.065 1   66.6   ? 322 GLN B CG  1 
ATOM   5815 C CD  . GLN C 1 152 ? -21.303 -11.286 -18.011 1   74.09  ? 322 GLN B CD  1 
ATOM   5816 O OE1 . GLN C 1 152 ? -21.101 -10.306 -18.734 1   74.89  ? 322 GLN B OE1 1 
ATOM   5817 N NE2 . GLN C 1 152 ? -20.393 -11.75  -17.17  1   64.01  ? 322 GLN B NE2 1 
ATOM   5818 N N   . GLN C 1 153 ? -23.822 -15.259 -20.968 1   80.95  ? 323 GLN B N   1 
ATOM   5819 C CA  . GLN C 1 153 ? -23.546 -16.229 -22.056 1   87.79  ? 323 GLN B CA  1 
ATOM   5820 C C   . GLN C 1 153 ? -23.351 -15.457 -23.366 1   87.17  ? 323 GLN B C   1 
ATOM   5821 O O   . GLN C 1 153 ? -24.358 -15.077 -23.992 1   83.09  ? 323 GLN B O   1 
ATOM   5822 C CB  . GLN C 1 153 ? -24.68  -17.238 -22.21  1   88.82  ? 323 GLN B CB  1 
ATOM   5823 C CG  . GLN C 1 153 ? -24.391 -18.33  -23.234 1   100.88 ? 323 GLN B CG  1 
ATOM   5824 C CD  . GLN C 1 153 ? -23.226 -19.217 -22.851 1   110.58 ? 323 GLN B CD  1 
ATOM   5825 O OE1 . GLN C 1 153 ? -23.235 -19.879 -21.808 1   115.65 ? 323 GLN B OE1 1 
ATOM   5826 N NE2 . GLN C 1 153 ? -22.207 -19.24  -23.698 1   105.45 ? 323 GLN B NE2 1 
ATOM   5827 N N   . PRO C 1 154 ? -22.098 -15.214 -23.802 1   80.91  ? 324 PRO B N   1 
ATOM   5828 C CA  . PRO C 1 154 ? -20.939 -15.553 -22.996 1   72.68  ? 324 PRO B CA  1 
ATOM   5829 C C   . PRO C 1 154 ? -20.527 -14.404 -22.099 1   64.7   ? 324 PRO B C   1 
ATOM   5830 O O   . PRO C 1 154 ? -21.171 -13.343 -22.115 1   61.37  ? 324 PRO B O   1 
ATOM   5831 C CB  . PRO C 1 154 ? -19.944 -15.801 -24.12  1   71.04  ? 324 PRO B CB  1 
ATOM   5832 C CG  . PRO C 1 154 ? -20.252 -14.712 -25.114 1   71.29  ? 324 PRO B CG  1 
ATOM   5833 C CD  . PRO C 1 154 ? -21.764 -14.61  -25.08  1   74.71  ? 324 PRO B CD  1 
ATOM   5834 N N   . ALA C 1 155 ? -19.465 -14.601 -21.325 1   61.02  ? 325 ALA B N   1 
ATOM   5835 C CA  . ALA C 1 155 ? -18.957 -13.503 -20.474 1   55.09  ? 325 ALA B CA  1 
ATOM   5836 C C   . ALA C 1 155 ? -18.599 -12.311 -21.349 1   56.03  ? 325 ALA B C   1 
ATOM   5837 O O   . ALA C 1 155 ? -18.128 -12.499 -22.482 1   61.01  ? 325 ALA B O   1 
ATOM   5838 C CB  . ALA C 1 155 ? -17.777 -13.96  -19.672 1   47.92  ? 325 ALA B CB  1 
ATOM   5839 N N   . ASN C 1 156 ? -18.802 -11.114 -20.823 1   52.34  ? 326 ASN B N   1 
ATOM   5840 C CA  . ASN C 1 156 ? -18.551 -9.912  -21.607 1   52.87  ? 326 ASN B CA  1 
ATOM   5841 C C   . ASN C 1 156 ? -18.044 -8.83   -20.661 1   52.89  ? 326 ASN B C   1 
ATOM   5842 O O   . ASN C 1 156 ? -18.76  -8.464  -19.73  1   52.83  ? 326 ASN B O   1 
ATOM   5843 C CB  . ASN C 1 156 ? -19.8   -9.434  -22.344 1   53.19  ? 326 ASN B CB  1 
ATOM   5844 C CG  . ASN C 1 156 ? -19.533 -8.231  -23.227 1   57.76  ? 326 ASN B CG  1 
ATOM   5845 O OD1 . ASN C 1 156 ? -19.076 -7.179  -22.757 1   59.45  ? 326 ASN B OD1 1 
ATOM   5846 N ND2 . ASN C 1 156 ? -19.836 -8.342  -24.511 1   57.83  ? 326 ASN B ND2 1 
ATOM   5847 N N   A CYS C 1 157 ? -16.824 -8.327  -20.901 0.5 53.89  ? 327 CYS B N   1 
ATOM   5848 N N   B CYS C 1 157 ? -16.837 -8.315  -20.953 0.5 52.22  ? 327 CYS B N   1 
ATOM   5849 C CA  A CYS C 1 157 ? -16.119 -7.479  -19.945 0.5 52.22  ? 327 CYS B CA  1 
ATOM   5850 C CA  B CYS C 1 157 ? -16.054 -7.47   -20.056 0.5 49.82  ? 327 CYS B CA  1 
ATOM   5851 C C   A CYS C 1 157 ? -16.704 -6.066  -19.912 0.5 48.7   ? 327 CYS B C   1 
ATOM   5852 C C   B CYS C 1 157 ? -16.688 -6.086  -19.934 0.5 47.46  ? 327 CYS B C   1 
ATOM   5853 O O   A CYS C 1 157 ? -16.699 -5.424  -18.869 0.5 46.97  ? 327 CYS B O   1 
ATOM   5854 O O   B CYS C 1 157 ? -16.716 -5.504  -18.857 0.5 46.06  ? 327 CYS B O   1 
ATOM   5855 C CB  A CYS C 1 157 ? -14.609 -7.506  -20.188 0.5 56.61  ? 327 CYS B CB  1 
ATOM   5856 C CB  B CYS C 1 157 ? -14.578 -7.429  -20.473 0.5 50.72  ? 327 CYS B CB  1 
ATOM   5857 S SG  A CYS C 1 157 ? -13.788 -9.02   -19.614 0.5 58.34  ? 327 CYS B SG  1 
ATOM   5858 S SG  B CYS C 1 157 ? -14.237 -6.578  -22.04  0.5 49.9   ? 327 CYS B SG  1 
ATOM   5859 N N   . LYS C 1 158 ? -17.212 -5.581  -21.049 1   49.68  ? 328 LYS B N   1 
ATOM   5860 C CA  . LYS C 1 158 ? -17.962 -4.329  -21.062 1   51.54  ? 328 LYS B CA  1 
ATOM   5861 C C   . LYS C 1 158 ? -19.198 -4.43   -20.159 1   47.64  ? 328 LYS B C   1 
ATOM   5862 O O   . LYS C 1 158 ? -19.498 -3.498  -19.425 1   45.58  ? 328 LYS B O   1 
ATOM   5863 C CB  . LYS C 1 158 ? -18.273 -3.931  -22.512 1   55.62  ? 328 LYS B CB  1 
ATOM   5864 C CG  . LYS C 1 158 ? -17.178 -3.111  -23.133 1   62.08  ? 328 LYS B CG  1 
ATOM   5865 C CD  . LYS C 1 158 ? -16.871 -3.553  -24.552 1   82.21  ? 328 LYS B CD  1 
ATOM   5866 C CE  . LYS C 1 158 ? -17.965 -3.491  -25.595 1   93.16  ? 328 LYS B CE  1 
ATOM   5867 N NZ  . LYS C 1 158 ? -18.403 -2.154  -26.012 1   93.51  ? 328 LYS B NZ  1 
ATOM   5868 N N   . VAL C 1 159 ? -19.89  -5.578  -20.177 1   47.66  ? 329 VAL B N   1 
ATOM   5869 C CA  . VAL C 1 159 ? -21.103 -5.754  -19.379 1   47.77  ? 329 VAL B CA  1 
ATOM   5870 C C   . VAL C 1 159 ? -20.709 -5.688  -17.907 1   47.58  ? 329 VAL B C   1 
ATOM   5871 O O   . VAL C 1 159 ? -21.346 -4.982  -17.12  1   47.02  ? 329 VAL B O   1 
ATOM   5872 C CB  . VAL C 1 159 ? -21.89  -7.046  -19.691 1   43.85  ? 329 VAL B CB  1 
ATOM   5873 C CG1 . VAL C 1 159 ? -23.011 -7.294  -18.695 1   42.86  ? 329 VAL B CG1 1 
ATOM   5874 C CG2 . VAL C 1 159 ? -22.441 -7.044  -21.099 1   43.71  ? 329 VAL B CG2 1 
ATOM   5875 N N   . GLU C 1 160 ? -19.641 -6.422  -17.557 1   47.34  ? 330 GLU B N   1 
ATOM   5876 C CA  . GLU C 1 160 ? -19.243 -6.506  -16.162 1   47.23  ? 330 GLU B CA  1 
ATOM   5877 C C   . GLU C 1 160 ? -18.888 -5.112  -15.67  1   46.39  ? 330 GLU B C   1 
ATOM   5878 O O   . GLU C 1 160 ? -19.492 -4.635  -14.72  1   44.09  ? 330 GLU B O   1 
ATOM   5879 C CB  . GLU C 1 160 ? -18.113 -7.517  -15.989 1   49.74  ? 330 GLU B CB  1 
ATOM   5880 C CG  . GLU C 1 160 ? -18.554 -8.937  -16.347 1   52.44  ? 330 GLU B CG  1 
ATOM   5881 C CD  . GLU C 1 160 ? -17.528 -10.039 -16.115 1   49.76  ? 330 GLU B CD  1 
ATOM   5882 O OE1 . GLU C 1 160 ? -16.544 -9.781  -15.425 1   55.75  ? 330 GLU B OE1 1 
ATOM   5883 O OE2 . GLU C 1 160 ? -17.664 -11.155 -16.627 1   48.67  ? 330 GLU B OE2 1 
ATOM   5884 N N   . SER C 1 161 ? -17.936 -4.464  -16.353 1   49.25  ? 331 SER B N   1 
ATOM   5885 C CA  . SER C 1 161 ? -17.484 -3.13   -15.965 1   48.35  ? 331 SER B CA  1 
ATOM   5886 C C   . SER C 1 161 ? -18.648 -2.126  -15.928 1   48.19  ? 331 SER B C   1 
ATOM   5887 O O   . SER C 1 161 ? -18.707 -1.286  -15.029 1   47.02  ? 331 SER B O   1 
ATOM   5888 C CB  . SER C 1 161 ? -16.331 -2.649  -16.84  1   46.63  ? 331 SER B CB  1 
ATOM   5889 O OG  . SER C 1 161 ? -15.152 -3.392  -16.577 1   47.41  ? 331 SER B OG  1 
ATOM   5890 N N   . LEU C 1 162 ? -19.567 -2.195  -16.905 1   46.15  ? 332 LEU B N   1 
ATOM   5891 C CA  . LEU C 1 162 ? -20.673 -1.248  -16.923 1   46.9   ? 332 LEU B CA  1 
ATOM   5892 C C   . LEU C 1 162 ? -21.551 -1.484  -15.69  1   45.96  ? 332 LEU B C   1 
ATOM   5893 O O   . LEU C 1 162 ? -22.006 -0.524  -15.063 1   47.68  ? 332 LEU B O   1 
ATOM   5894 C CB  . LEU C 1 162 ? -21.479 -1.312  -18.221 1   45.7   ? 332 LEU B CB  1 
ATOM   5895 C CG  . LEU C 1 162 ? -22.648 -0.327  -18.335 1   45.62  ? 332 LEU B CG  1 
ATOM   5896 C CD1 . LEU C 1 162 ? -22.224 1.1     -18.084 1   45.29  ? 332 LEU B CD1 1 
ATOM   5897 C CD2 . LEU C 1 162 ? -23.321 -0.396  -19.694 1   44.88  ? 332 LEU B CD2 1 
ATOM   5898 N N   . ALA C 1 163 ? -21.752 -2.759  -15.317 1   44.17  ? 333 ALA B N   1 
ATOM   5899 C CA  . ALA C 1 163 ? -22.55  -3.074  -14.134 1   43.43  ? 333 ALA B CA  1 
ATOM   5900 C C   . ALA C 1 163 ? -21.898 -2.518  -12.877 1   43.26  ? 333 ALA B C   1 
ATOM   5901 O O   . ALA C 1 163 ? -22.626 -1.969  -12.049 1   41.55  ? 333 ALA B O   1 
ATOM   5902 C CB  . ALA C 1 163 ? -22.821 -4.543  -13.989 1   38.77  ? 333 ALA B CB  1 
ATOM   5903 N N   . MET C 1 164 ? -20.555 -2.657  -12.766 1   43.61  ? 334 MET B N   1 
ATOM   5904 C CA  . MET C 1 164 ? -19.803 -2.222  -11.586 1   42.61  ? 334 MET B CA  1 
ATOM   5905 C C   . MET C 1 164 ? -19.954 -0.708  -11.446 1   41.69  ? 334 MET B C   1 
ATOM   5906 O O   . MET C 1 164 ? -20.167 -0.198  -10.346 1   44.07  ? 334 MET B O   1 
ATOM   5907 C CB  . MET C 1 164 ? -18.301 -2.534  -11.699 1   47     ? 334 MET B CB  1 
ATOM   5908 C CG  . MET C 1 164 ? -17.881 -3.982  -11.466 1   53.48  ? 334 MET B CG  1 
ATOM   5909 S SD  . MET C 1 164 ? -18.282 -4.464  -9.768  1   60.99  ? 334 MET B SD  1 
ATOM   5910 C CE  . MET C 1 164 ? -17.849 -6.208  -9.778  1   59.42  ? 334 MET B CE  1 
ATOM   5911 N N   . PHE C 1 165 ? -19.855 -0.009  -12.586 1   41.22  ? 335 PHE B N   1 
ATOM   5912 C CA  . PHE C 1 165 ? -19.946 1.436   -12.653 1   41.78  ? 335 PHE B CA  1 
ATOM   5913 C C   . PHE C 1 165 ? -21.306 1.907   -12.156 1   42.52  ? 335 PHE B C   1 
ATOM   5914 O O   . PHE C 1 165 ? -21.392 2.757   -11.282 1   44.67  ? 335 PHE B O   1 
ATOM   5915 C CB  . PHE C 1 165 ? -19.721 1.835   -14.109 1   43.73  ? 335 PHE B CB  1 
ATOM   5916 C CG  . PHE C 1 165 ? -20.032 3.281   -14.452 1   43.97  ? 335 PHE B CG  1 
ATOM   5917 C CD1 . PHE C 1 165 ? -19.332 4.322   -13.864 1   42.8   ? 335 PHE B CD1 1 
ATOM   5918 C CD2 . PHE C 1 165 ? -21.026 3.575   -15.372 1   46.47  ? 335 PHE B CD2 1 
ATOM   5919 C CE1 . PHE C 1 165 ? -19.604 5.632   -14.211 1   46.94  ? 335 PHE B CE1 1 
ATOM   5920 C CE2 . PHE C 1 165 ? -21.314 4.884   -15.724 1   48.44  ? 335 PHE B CE2 1 
ATOM   5921 C CZ  . PHE C 1 165 ? -20.599 5.912   -15.144 1   50.24  ? 335 PHE B CZ  1 
ATOM   5922 N N   . LEU C 1 166 ? -22.375 1.32    -12.69  1   43.59  ? 336 LEU B N   1 
ATOM   5923 C CA  . LEU C 1 166 ? -23.726 1.722   -12.325 1   41.48  ? 336 LEU B CA  1 
ATOM   5924 C C   . LEU C 1 166 ? -23.934 1.478   -10.837 1   42.12  ? 336 LEU B C   1 
ATOM   5925 O O   . LEU C 1 166 ? -24.503 2.32    -10.146 1   41.66  ? 336 LEU B O   1 
ATOM   5926 C CB  . LEU C 1 166 ? -24.711 0.932   -13.181 1   39.78  ? 336 LEU B CB  1 
ATOM   5927 C CG  . LEU C 1 166 ? -24.655 1.247   -14.677 1   40.42  ? 336 LEU B CG  1 
ATOM   5928 C CD1 . LEU C 1 166 ? -25.575 0.311   -15.396 1   40.23  ? 336 LEU B CD1 1 
ATOM   5929 C CD2 . LEU C 1 166 ? -25.042 2.692   -14.952 1   40.66  ? 336 LEU B CD2 1 
ATOM   5930 N N   . GLY C 1 167 ? -23.412 0.337   -10.358 1   43.5   ? 337 GLY B N   1 
ATOM   5931 C CA  . GLY C 1 167 ? -23.458 -0.015  -8.952  1   39.07  ? 337 GLY B CA  1 
ATOM   5932 C C   . GLY C 1 167 ? -22.825 1.09    -8.121  1   41.59  ? 337 GLY B C   1 
ATOM   5933 O O   . GLY C 1 167 ? -23.452 1.561   -7.173  1   41.66  ? 337 GLY B O   1 
ATOM   5934 N N   . GLU C 1 168 ? -21.635 1.553   -8.546  1   41.15  ? 338 GLU B N   1 
ATOM   5935 C CA  . GLU C 1 168 ? -20.929 2.566   -7.771  1   43.16  ? 338 GLU B CA  1 
ATOM   5936 C C   . GLU C 1 168 ? -21.693 3.885   -7.808  1   41.45  ? 338 GLU B C   1 
ATOM   5937 O O   . GLU C 1 168 ? -21.734 4.58    -6.8    1   41.93  ? 338 GLU B O   1 
ATOM   5938 C CB  . GLU C 1 168 ? -19.477 2.829   -8.2    1   42.15  ? 338 GLU B CB  1 
ATOM   5939 C CG  . GLU C 1 168 ? -18.537 1.719   -7.766  1   40.09  ? 338 GLU B CG  1 
ATOM   5940 C CD  . GLU C 1 168 ? -17.073 1.993   -8.061  1   42.73  ? 338 GLU B CD  1 
ATOM   5941 O OE1 . GLU C 1 168 ? -16.554 3.129   -7.902  1   40.41  ? 338 GLU B OE1 1 
ATOM   5942 O OE2 . GLU C 1 168 ? -16.42  0.997   -8.409  1   42.79  ? 338 GLU B OE2 1 
ATOM   5943 N N   . LEU C 1 169 ? -22.282 4.236   -8.952  1   40.61  ? 339 LEU B N   1 
ATOM   5944 C CA  . LEU C 1 169 ? -23.037 5.485   -9.022  1   43.59  ? 339 LEU B CA  1 
ATOM   5945 C C   . LEU C 1 169 ? -24.07  5.573   -7.899  1   41.99  ? 339 LEU B C   1 
ATOM   5946 O O   . LEU C 1 169 ? -24.318 6.66    -7.378  1   41.36  ? 339 LEU B O   1 
ATOM   5947 C CB  . LEU C 1 169 ? -23.686 5.717   -10.386 1   43.28  ? 339 LEU B CB  1 
ATOM   5948 C CG  . LEU C 1 169 ? -22.733 5.961   -11.56  1   46.99  ? 339 LEU B CG  1 
ATOM   5949 C CD1 . LEU C 1 169 ? -23.532 6.215   -12.817 1   46.61  ? 339 LEU B CD1 1 
ATOM   5950 C CD2 . LEU C 1 169 ? -21.745 7.108   -11.311 1   47.22  ? 339 LEU B CD2 1 
ATOM   5951 N N   . SER C 1 170 ? -24.636 4.423   -7.518  1   41.27  ? 340 SER B N   1 
ATOM   5952 C CA  . SER C 1 170 ? -25.735 4.388   -6.56   1   45.55  ? 340 SER B CA  1 
ATOM   5953 C C   . SER C 1 170 ? -25.264 4.652   -5.121  1   47.6   ? 340 SER B C   1 
ATOM   5954 O O   . SER C 1 170 ? -26.047 5.073   -4.267  1   49.37  ? 340 SER B O   1 
ATOM   5955 C CB  . SER C 1 170 ? -26.491 3.08    -6.663  1   44.57  ? 340 SER B CB  1 
ATOM   5956 O OG  . SER C 1 170 ? -25.784 2.021   -6.047  1   46.88  ? 340 SER B OG  1 
ATOM   5957 N N   . LEU C 1 171 ? -23.979 4.399   -4.842  1   43.38  ? 341 LEU B N   1 
ATOM   5958 C CA  . LEU C 1 171 ? -23.391 4.728   -3.557  1   44.09  ? 341 LEU B CA  1 
ATOM   5959 C C   . LEU C 1 171 ? -23.493 6.227   -3.251  1   44.56  ? 341 LEU B C   1 
ATOM   5960 O O   . LEU C 1 171 ? -23.59  6.607   -2.077  1   44.36  ? 341 LEU B O   1 
ATOM   5961 C CB  . LEU C 1 171 ? -21.928 4.28    -3.604  1   44.87  ? 341 LEU B CB  1 
ATOM   5962 C CG  . LEU C 1 171 ? -21.679 2.767   -3.712  1   42.62  ? 341 LEU B CG  1 
ATOM   5963 C CD1 . LEU C 1 171 ? -20.168 2.55    -3.805  1   40.39  ? 341 LEU B CD1 1 
ATOM   5964 C CD2 . LEU C 1 171 ? -22.294 1.945   -2.555  1   38.79  ? 341 LEU B CD2 1 
ATOM   5965 N N   . ILE C 1 172 ? -23.438 7.067   -4.302  1   42.37  ? 342 ILE B N   1 
ATOM   5966 C CA  . ILE C 1 172 ? -23.377 8.511   -4.159  1   42.73  ? 342 ILE B CA  1 
ATOM   5967 C C   . ILE C 1 172 ? -24.67  9.091   -3.577  1   46.3   ? 342 ILE B C   1 
ATOM   5968 O O   . ILE C 1 172 ? -24.61  10.041  -2.801  1   48.33  ? 342 ILE B O   1 
ATOM   5969 C CB  . ILE C 1 172 ? -23.083 9.174   -5.507  1   44.49  ? 342 ILE B CB  1 
ATOM   5970 C CG1 . ILE C 1 172 ? -21.715 8.791   -6.058  1   41.48  ? 342 ILE B CG1 1 
ATOM   5971 C CG2 . ILE C 1 172 ? -23.211 10.695  -5.375  1   48.16  ? 342 ILE B CG2 1 
ATOM   5972 C CD1 . ILE C 1 172 ? -20.583 9.328   -5.223  1   42.98  ? 342 ILE B CD1 1 
ATOM   5973 N N   . ASP C 1 173 ? -25.826 8.57    -4.007  1   46.37  ? 343 ASP B N   1 
ATOM   5974 C CA  . ASP C 1 173 ? -27.109 9.229   -3.836  1   47.94  ? 343 ASP B CA  1 
ATOM   5975 C C   . ASP C 1 173 ? -28     8.395   -2.927  1   49.89  ? 343 ASP B C   1 
ATOM   5976 O O   . ASP C 1 173 ? -28.677 7.478   -3.412  1   52.73  ? 343 ASP B O   1 
ATOM   5977 C CB  . ASP C 1 173 ? -27.797 9.444   -5.169  1   47.16  ? 343 ASP B CB  1 
ATOM   5978 C CG  . ASP C 1 173 ? -27.014 10.312  -6.14   1   48.69  ? 343 ASP B CG  1 
ATOM   5979 O OD1 . ASP C 1 173 ? -26.638 11.429  -5.727  1   51.14  ? 343 ASP B OD1 1 
ATOM   5980 O OD2 . ASP C 1 173 ? -26.765 9.858   -7.277  1   46.62  ? 343 ASP B OD2 1 
ATOM   5981 N N   . ALA C 1 174 ? -27.99  8.715   -1.632  1   48.1   ? 344 ALA B N   1 
ATOM   5982 C CA  . ALA C 1 174 ? -28.815 8.004   -0.63   1   49.46  ? 344 ALA B CA  1 
ATOM   5983 C C   . ALA C 1 174 ? -30.277 8.087   -1.036  1   50.65  ? 344 ALA B C   1 
ATOM   5984 O O   . ALA C 1 174 ? -31.025 7.148   -0.745  1   56.14  ? 344 ALA B O   1 
ATOM   5985 C CB  . ALA C 1 174 ? -28.585 8.627   0.705   1   53.9   ? 344 ALA B CB  1 
ATOM   5986 N N   . ASP C 1 175 ? -30.677 9.202   -1.636  1   49.29  ? 345 ASP B N   1 
ATOM   5987 C CA  . ASP C 1 175 ? -32.038 9.28    -2.217  1   51.14  ? 345 ASP B CA  1 
ATOM   5988 C C   . ASP C 1 175 ? -31.869 9.095   -3.723  1   51.08  ? 345 ASP B C   1 
ATOM   5989 O O   . ASP C 1 175 ? -31.333 10.003  -4.365  1   53.73  ? 345 ASP B O   1 
ATOM   5990 C CB  . ASP C 1 175 ? -32.742 10.577  -1.858  1   52.5   ? 345 ASP B CB  1 
ATOM   5991 C CG  . ASP C 1 175 ? -34.098 10.805  -2.507  1   54.65  ? 345 ASP B CG  1 
ATOM   5992 O OD1 . ASP C 1 175 ? -34.785 9.811   -2.807  1   52.31  ? 345 ASP B OD1 1 
ATOM   5993 O OD2 . ASP C 1 175 ? -34.459 11.98   -2.698  1   55.44  ? 345 ASP B OD2 1 
ATOM   5994 N N   . PRO C 1 176 ? -32.281 7.954   -4.304  1   54.33  ? 346 PRO B N   1 
ATOM   5995 C CA  . PRO C 1 176 ? -33.081 6.982   -3.568  1   52.87  ? 346 PRO B CA  1 
ATOM   5996 C C   . PRO C 1 176 ? -32.519 5.622   -3.207  1   51.3   ? 346 PRO B C   1 
ATOM   5997 O O   . PRO C 1 176 ? -33.283 4.814   -2.693  1   53.36  ? 346 PRO B O   1 
ATOM   5998 C CB  . PRO C 1 176 ? -34.031 6.82    -4.735  1   49.33  ? 346 PRO B CB  1 
ATOM   5999 C CG  . PRO C 1 176 ? -33.117 6.562   -5.903  1   49.62  ? 346 PRO B CG  1 
ATOM   6000 C CD  . PRO C 1 176 ? -32.051 7.611   -5.692  1   50.32  ? 346 PRO B CD  1 
ATOM   6001 N N   . TYR C 1 177 ? -31.223 5.39    -3.374  1   47.19  ? 347 TYR B N   1 
ATOM   6002 C CA  . TYR C 1 177 ? -30.682 4.007   -3.255  1   44.37  ? 347 TYR B CA  1 
ATOM   6003 C C   . TYR C 1 177 ? -30.684 3.457   -1.838  1   44.35  ? 347 TYR B C   1 
ATOM   6004 O O   . TYR C 1 177 ? -30.553 2.237   -1.715  1   46.6   ? 347 TYR B O   1 
ATOM   6005 C CB  . TYR C 1 177 ? -29.347 4.048   -4.005  1   40.8   ? 347 TYR B CB  1 
ATOM   6006 C CG  . TYR C 1 177 ? -29.593 4.377   -5.466  1   40.63  ? 347 TYR B CG  1 
ATOM   6007 C CD1 . TYR C 1 177 ? -30.343 3.527   -6.267  1   41.51  ? 347 TYR B CD1 1 
ATOM   6008 C CD2 . TYR C 1 177 ? -29.123 5.556   -6.023  1   39.89  ? 347 TYR B CD2 1 
ATOM   6009 C CE1 . TYR C 1 177 ? -30.596 3.827   -7.592  1   42.81  ? 347 TYR B CE1 1 
ATOM   6010 C CE2 . TYR C 1 177 ? -29.366 5.867   -7.346  1   42.57  ? 347 TYR B CE2 1 
ATOM   6011 C CZ  . TYR C 1 177 ? -30.106 5.001   -8.128  1   44.03  ? 347 TYR B CZ  1 
ATOM   6012 O OH  . TYR C 1 177 ? -30.341 5.32    -9.424  1   45.39  ? 347 TYR B OH  1 
ATOM   6013 N N   . LEU C 1 178 ? -30.846 4.287   -0.814  1   46.58  ? 348 LEU B N   1 
ATOM   6014 C CA  . LEU C 1 178 ? -30.886 3.679   0.503   1   45.47  ? 348 LEU B CA  1 
ATOM   6015 C C   . LEU C 1 178 ? -32.094 2.747   0.582   1   45.82  ? 348 LEU B C   1 
ATOM   6016 O O   . LEU C 1 178 ? -32.083 1.788   1.334   1   45.91  ? 348 LEU B O   1 
ATOM   6017 C CB  . LEU C 1 178 ? -30.964 4.733   1.605   1   48.14  ? 348 LEU B CB  1 
ATOM   6018 C CG  . LEU C 1 178 ? -29.654 5.356   2.079   1   49.24  ? 348 LEU B CG  1 
ATOM   6019 C CD1 . LEU C 1 178 ? -29.955 6.309   3.256   1   46.76  ? 348 LEU B CD1 1 
ATOM   6020 C CD2 . LEU C 1 178 ? -28.615 4.265   2.428   1   47.56  ? 348 LEU B CD2 1 
ATOM   6021 N N   . LYS C 1 179 ? -33.149 3.033   -0.172  1   46.52  ? 349 LYS B N   1 
ATOM   6022 C CA  . LYS C 1 179 ? -34.337 2.202   -0.063  1   50.24  ? 349 LYS B CA  1 
ATOM   6023 C C   . LYS C 1 179 ? -34.137 0.821   -0.697  1   50.47  ? 349 LYS B C   1 
ATOM   6024 O O   . LYS C 1 179 ? -34.972 -0.058  -0.513  1   51.79  ? 349 LYS B O   1 
ATOM   6025 C CB  . LYS C 1 179 ? -35.547 2.932   -0.646  1   55.08  ? 349 LYS B CB  1 
ATOM   6026 C CG  . LYS C 1 179 ? -35.596 3.094   -2.145  1   64.98  ? 349 LYS B CG  1 
ATOM   6027 C CD  . LYS C 1 179 ? -36.84  3.866   -2.62   1   73.05  ? 349 LYS B CD  1 
ATOM   6028 C CE  . LYS C 1 179 ? -36.961 5.286   -2.156  1   73.93  ? 349 LYS B CE  1 
ATOM   6029 N NZ  . LYS C 1 179 ? -37.83  6.017   -3.082  1   82.54  ? 349 LYS B NZ  1 
ATOM   6030 N N   . TYR C 1 180 ? -33.028 0.59    -1.417  1   45.17  ? 350 TYR B N   1 
ATOM   6031 C CA  . TYR C 1 180 ? -32.868 -0.705  -2.062  1   44.6   ? 350 TYR B CA  1 
ATOM   6032 C C   . TYR C 1 180 ? -31.727 -1.506  -1.442  1   45.71  ? 350 TYR B C   1 
ATOM   6033 O O   . TYR C 1 180 ? -30.673 -0.962  -1.068  1   43.24  ? 350 TYR B O   1 
ATOM   6034 C CB  . TYR C 1 180 ? -32.623 -0.557  -3.563  1   45.7   ? 350 TYR B CB  1 
ATOM   6035 C CG  . TYR C 1 180 ? -33.66  0.25    -4.334  1   46.34  ? 350 TYR B CG  1 
ATOM   6036 C CD1 . TYR C 1 180 ? -34.966 -0.228  -4.487  1   45.61  ? 350 TYR B CD1 1 
ATOM   6037 C CD2 . TYR C 1 180 ? -33.334 1.49    -4.893  1   43.38  ? 350 TYR B CD2 1 
ATOM   6038 C CE1 . TYR C 1 180 ? -35.917 0.493   -5.196  1   46.31  ? 350 TYR B CE1 1 
ATOM   6039 C CE2 . TYR C 1 180 ? -34.281 2.221   -5.594  1   46.29  ? 350 TYR B CE2 1 
ATOM   6040 C CZ  . TYR C 1 180 ? -35.567 1.718   -5.751  1   47.39  ? 350 TYR B CZ  1 
ATOM   6041 O OH  . TYR C 1 180 ? -36.46  2.441   -6.487  1   48.27  ? 350 TYR B OH  1 
ATOM   6042 N N   . LEU C 1 181 ? -31.951 -2.826  -1.384  1   47.69  ? 351 LEU B N   1 
ATOM   6043 C CA  . LEU C 1 181 ? -30.96  -3.784  -0.911  1   45.55  ? 351 LEU B CA  1 
ATOM   6044 C C   . LEU C 1 181 ? -29.836 -3.894  -1.929  1   43.76  ? 351 LEU B C   1 
ATOM   6045 O O   . LEU C 1 181 ? -30.019 -3.656  -3.118  1   46.05  ? 351 LEU B O   1 
ATOM   6046 C CB  . LEU C 1 181 ? -31.64  -5.134  -0.683  1   45.97  ? 351 LEU B CB  1 
ATOM   6047 C CG  . LEU C 1 181 ? -32.622 -5.184  0.497   1   47.4   ? 351 LEU B CG  1 
ATOM   6048 C CD1 . LEU C 1 181 ? -33.527 -6.395  0.444   1   46.51  ? 351 LEU B CD1 1 
ATOM   6049 C CD2 . LEU C 1 181 ? -31.869 -5.165  1.82    1   47.09  ? 351 LEU B CD2 1 
ATOM   6050 N N   . PRO C 1 182 ? -28.615 -4.231  -1.497  1   43.08  ? 352 PRO B N   1 
ATOM   6051 C CA  . PRO C 1 182 ? -27.523 -4.445  -2.452  1   40.41  ? 352 PRO B CA  1 
ATOM   6052 C C   . PRO C 1 182 ? -27.848 -5.421  -3.58   1   39.32  ? 352 PRO B C   1 
ATOM   6053 O O   . PRO C 1 182 ? -27.453 -5.187  -4.714  1   36.67  ? 352 PRO B O   1 
ATOM   6054 C CB  . PRO C 1 182 ? -26.401 -4.945  -1.553  1   39.02  ? 352 PRO B CB  1 
ATOM   6055 C CG  . PRO C 1 182 ? -26.686 -4.281  -0.219  1   38.96  ? 352 PRO B CG  1 
ATOM   6056 C CD  . PRO C 1 182 ? -28.187 -4.264  -0.088  1   41.01  ? 352 PRO B CD  1 
ATOM   6057 N N   . SER C 1 183 ? -28.622 -6.476  -3.281  1   40.68  ? 353 SER B N   1 
ATOM   6058 C CA  . SER C 1 183 ? -28.882 -7.552  -4.23   1   39.33  ? 353 SER B CA  1 
ATOM   6059 C C   . SER C 1 183 ? -29.76  -7.065  -5.37   1   42.61  ? 353 SER B C   1 
ATOM   6060 O O   . SER C 1 183 ? -29.635 -7.587  -6.488  1   40.92  ? 353 SER B O   1 
ATOM   6061 C CB  . SER C 1 183 ? -29.523 -8.744  -3.567  1   42.11  ? 353 SER B CB  1 
ATOM   6062 O OG  . SER C 1 183 ? -30.774 -8.443  -2.956  1   39.63  ? 353 SER B OG  1 
ATOM   6063 N N   . VAL C 1 184 ? -30.652 -6.101  -5.04   1   41.67  ? 354 VAL B N   1 
ATOM   6064 C CA  . VAL C 1 184 ? -31.584 -5.496  -5.982  1   39.89  ? 354 VAL B CA  1 
ATOM   6065 C C   . VAL C 1 184 ? -30.86  -4.467  -6.856  1   39.7   ? 354 VAL B C   1 
ATOM   6066 O O   . VAL C 1 184 ? -31.064 -4.431  -8.069  1   41.13  ? 354 VAL B O   1 
ATOM   6067 C CB  . VAL C 1 184 ? -32.811 -4.906  -5.248  1   39.4   ? 354 VAL B CB  1 
ATOM   6068 C CG1 . VAL C 1 184 ? -33.652 -3.992  -6.139  1   37.74  ? 354 VAL B CG1 1 
ATOM   6069 C CG2 . VAL C 1 184 ? -33.683 -6.017  -4.671  1   38.64  ? 354 VAL B CG2 1 
ATOM   6070 N N   . ILE C 1 185 ? -30.064 -3.579  -6.252  1   38.56  ? 355 ILE B N   1 
ATOM   6071 C CA  . ILE C 1 185 ? -29.329 -2.602  -7.045  1   41.27  ? 355 ILE B CA  1 
ATOM   6072 C C   . ILE C 1 185 ? -28.384 -3.346  -7.996  1   39.78  ? 355 ILE B C   1 
ATOM   6073 O O   . ILE C 1 185 ? -28.182 -2.951  -9.139  1   39.21  ? 355 ILE B O   1 
ATOM   6074 C CB  . ILE C 1 185 ? -28.538 -1.62   -6.163  1   41.64  ? 355 ILE B CB  1 
ATOM   6075 C CG1 . ILE C 1 185 ? -29.451 -0.781  -5.286  1   41.23  ? 355 ILE B CG1 1 
ATOM   6076 C CG2 . ILE C 1 185 ? -27.662 -0.721  -7.032  1   40.68  ? 355 ILE B CG2 1 
ATOM   6077 C CD1 . ILE C 1 185 ? -28.689 0.018   -4.224  1   35.95  ? 355 ILE B CD1 1 
ATOM   6078 N N   . ALA C 1 186 ? -27.803 -4.436  -7.508  1   41.27  ? 356 ALA B N   1 
ATOM   6079 C CA  . ALA C 1 186 ? -26.914 -5.266  -8.315  1   40.96  ? 356 ALA B CA  1 
ATOM   6080 C C   . ALA C 1 186 ? -27.691 -5.883  -9.474  1   43.2   ? 356 ALA B C   1 
ATOM   6081 O O   . ALA C 1 186 ? -27.2   -5.97   -10.597 1   47.34  ? 356 ALA B O   1 
ATOM   6082 C CB  . ALA C 1 186 ? -26.295 -6.332  -7.452  1   37.74  ? 356 ALA B CB  1 
ATOM   6083 N N   . ALA C 1 187 ? -28.933 -6.27   -9.2    1   43.05  ? 357 ALA B N   1 
ATOM   6084 C CA  . ALA C 1 187 ? -29.769 -6.855  -10.227 1   41.19  ? 357 ALA B CA  1 
ATOM   6085 C C   . ALA C 1 187 ? -30.078 -5.784  -11.261 1   42.14  ? 357 ALA B C   1 
ATOM   6086 O O   . ALA C 1 187 ? -30.011 -6.045  -12.462 1   42.52  ? 357 ALA B O   1 
ATOM   6087 C CB  . ALA C 1 187 ? -31.04  -7.399  -9.604  1   43.61  ? 357 ALA B CB  1 
ATOM   6088 N N   . ALA C 1 188 ? -30.451 -4.58   -10.795 1   42.69  ? 358 ALA B N   1 
ATOM   6089 C CA  . ALA C 1 188 ? -30.842 -3.533  -11.734 1   42.59  ? 358 ALA B CA  1 
ATOM   6090 C C   . ALA C 1 188 ? -29.643 -3.173  -12.615 1   43.22  ? 358 ALA B C   1 
ATOM   6091 O O   . ALA C 1 188 ? -29.788 -2.893  -13.806 1   42.5   ? 358 ALA B O   1 
ATOM   6092 C CB  . ALA C 1 188 ? -31.35  -2.325  -10.989 1   41.99  ? 358 ALA B CB  1 
ATOM   6093 N N   . ALA C 1 189 ? -28.454 -3.17   -11.989 1   42.13  ? 359 ALA B N   1 
ATOM   6094 C CA  . ALA C 1 189 ? -27.224 -2.718  -12.609 1   39.51  ? 359 ALA B CA  1 
ATOM   6095 C C   . ALA C 1 189 ? -26.829 -3.746  -13.663 1   40.62  ? 359 ALA B C   1 
ATOM   6096 O O   . ALA C 1 189 ? -26.47  -3.37   -14.781 1   42.65  ? 359 ALA B O   1 
ATOM   6097 C CB  . ALA C 1 189 ? -26.165 -2.53   -11.538 1   37.83  ? 359 ALA B CB  1 
ATOM   6098 N N   . PHE C 1 190 ? -26.927 -5.044  -13.317 1   41.32  ? 360 PHE B N   1 
ATOM   6099 C CA  . PHE C 1 190 ? -26.583 -6.091  -14.268 1   42.08  ? 360 PHE B CA  1 
ATOM   6100 C C   . PHE C 1 190 ? -27.517 -6.001  -15.474 1   43.82  ? 360 PHE B C   1 
ATOM   6101 O O   . PHE C 1 190 ? -27.066 -5.913  -16.618 1   45.15  ? 360 PHE B O   1 
ATOM   6102 C CB  . PHE C 1 190 ? -26.612 -7.471  -13.62  1   40.96  ? 360 PHE B CB  1 
ATOM   6103 C CG  . PHE C 1 190 ? -26.219 -8.595  -14.567 1   43.34  ? 360 PHE B CG  1 
ATOM   6104 C CD1 . PHE C 1 190 ? -24.957 -8.635  -15.133 1   44.37  ? 360 PHE B CD1 1 
ATOM   6105 C CD2 . PHE C 1 190 ? -27.106 -9.612  -14.897 1   46.8   ? 360 PHE B CD2 1 
ATOM   6106 C CE1 . PHE C 1 190 ? -24.573 -9.668  -15.981 1   43.91  ? 360 PHE B CE1 1 
ATOM   6107 C CE2 . PHE C 1 190 ? -26.725 -10.633 -15.759 1   52.29  ? 360 PHE B CE2 1 
ATOM   6108 C CZ  . PHE C 1 190 ? -25.447 -10.677 -16.28  1   45.55  ? 360 PHE B CZ  1 
ATOM   6109 N N   . HIS C 1 191 ? -28.828 -5.959  -15.212 1   43.86  ? 361 HIS B N   1 
ATOM   6110 C CA  . HIS C 1 191 ? -29.809 -5.936  -16.3   1   42.25  ? 361 HIS B CA  1 
ATOM   6111 C C   . HIS C 1 191 ? -29.595 -4.722  -17.191 1   42.36  ? 361 HIS B C   1 
ATOM   6112 O O   . HIS C 1 191 ? -29.663 -4.788  -18.423 1   43.13  ? 361 HIS B O   1 
ATOM   6113 C CB  . HIS C 1 191 ? -31.254 -5.839  -15.808 1   39.35  ? 361 HIS B CB  1 
ATOM   6114 C CG  . HIS C 1 191 ? -32.127 -5.482  -16.946 1   40.43  ? 361 HIS B CG  1 
ATOM   6115 N ND1 . HIS C 1 191 ? -32.383 -6.393  -17.936 1   41.17  ? 361 HIS B ND1 1 
ATOM   6116 C CD2 . HIS C 1 191 ? -32.718 -4.333  -17.338 1   42.11  ? 361 HIS B CD2 1 
ATOM   6117 C CE1 . HIS C 1 191 ? -33.162 -5.828  -18.86  1   43.6   ? 361 HIS B CE1 1 
ATOM   6118 N NE2 . HIS C 1 191 ? -33.364 -4.571  -18.531 1   43.43  ? 361 HIS B NE2 1 
ATOM   6119 N N   . LEU C 1 192 ? -29.322 -3.59   -16.548 1   41.86  ? 362 LEU B N   1 
ATOM   6120 C CA  . LEU C 1 192 ? -29.178 -2.381  -17.335 1   42.06  ? 362 LEU B CA  1 
ATOM   6121 C C   . LEU C 1 192 ? -27.889 -2.438  -18.161 1   44.53  ? 362 LEU B C   1 
ATOM   6122 O O   . LEU C 1 192 ? -27.876 -2.067  -19.331 1   45.42  ? 362 LEU B O   1 
ATOM   6123 C CB  . LEU C 1 192 ? -29.205 -1.232  -16.346 1   39.53  ? 362 LEU B CB  1 
ATOM   6124 C CG  . LEU C 1 192 ? -29.258 0.145   -16.986 1   42.68  ? 362 LEU B CG  1 
ATOM   6125 C CD1 . LEU C 1 192 ? -30.301 0.146   -18.116 1   43.33  ? 362 LEU B CD1 1 
ATOM   6126 C CD2 . LEU C 1 192 ? -29.578 1.151   -15.904 1   42.78  ? 362 LEU B CD2 1 
ATOM   6127 N N   . ALA C 1 193 ? -26.82  -2.941  -17.546 1   42.18  ? 363 ALA B N   1 
ATOM   6128 C CA  . ALA C 1 193 ? -25.539 -3.035  -18.207 1   44.47  ? 363 ALA B CA  1 
ATOM   6129 C C   . ALA C 1 193 ? -25.64  -3.928  -19.436 1   46.85  ? 363 ALA B C   1 
ATOM   6130 O O   . ALA C 1 193 ? -25.138 -3.576  -20.524 1   47.69  ? 363 ALA B O   1 
ATOM   6131 C CB  . ALA C 1 193 ? -24.502 -3.564  -17.231 1   40.95  ? 363 ALA B CB  1 
ATOM   6132 N N   . LEU C 1 194 ? -26.255 -5.098  -19.208 1   48.49  ? 364 LEU B N   1 
ATOM   6133 C CA  . LEU C 1 194 ? -26.458 -6.136  -20.209 1   50.72  ? 364 LEU B CA  1 
ATOM   6134 C C   . LEU C 1 194 ? -27.274 -5.589  -21.373 1   52.18  ? 364 LEU B C   1 
ATOM   6135 O O   . LEU C 1 194 ? -26.899 -5.755  -22.546 1   56.99  ? 364 LEU B O   1 
ATOM   6136 C CB  . LEU C 1 194 ? -27.192 -7.265  -19.485 1   53.15  ? 364 LEU B CB  1 
ATOM   6137 C CG  . LEU C 1 194 ? -27.541 -8.514  -20.295 1   57.73  ? 364 LEU B CG  1 
ATOM   6138 C CD1 . LEU C 1 194 ? -26.325 -9.343  -20.698 1   57.96  ? 364 LEU B CD1 1 
ATOM   6139 C CD2 . LEU C 1 194 ? -28.477 -9.344  -19.434 1   61.5   ? 364 LEU B CD2 1 
ATOM   6140 N N   . TYR C 1 195 ? -28.386 -4.922  -21.033 1   50.48  ? 365 TYR B N   1 
ATOM   6141 C CA  . TYR C 1 195 ? -29.255 -4.339  -22.04  1   49.88  ? 365 TYR B CA  1 
ATOM   6142 C C   . TYR C 1 195 ? -28.492 -3.297  -22.856 1   50.83  ? 365 TYR B C   1 
ATOM   6143 O O   . TYR C 1 195 ? -28.641 -3.229  -24.057 1   52.03  ? 365 TYR B O   1 
ATOM   6144 C CB  . TYR C 1 195 ? -30.471 -3.699  -21.367 1   49.51  ? 365 TYR B CB  1 
ATOM   6145 C CG  . TYR C 1 195 ? -31.488 -3.192  -22.369 1   51.55  ? 365 TYR B CG  1 
ATOM   6146 C CD1 . TYR C 1 195 ? -32.162 -4.069  -23.197 1   52.51  ? 365 TYR B CD1 1 
ATOM   6147 C CD2 . TYR C 1 195 ? -31.735 -1.846  -22.514 1   53.58  ? 365 TYR B CD2 1 
ATOM   6148 C CE1 . TYR C 1 195 ? -33.065 -3.621  -24.141 1   56.63  ? 365 TYR B CE1 1 
ATOM   6149 C CE2 . TYR C 1 195 ? -32.648 -1.383  -23.444 1   56.6   ? 365 TYR B CE2 1 
ATOM   6150 C CZ  . TYR C 1 195 ? -33.31  -2.269  -24.276 1   60.08  ? 365 TYR B CZ  1 
ATOM   6151 O OH  . TYR C 1 195 ? -34.233 -1.829  -25.206 1   67.01  ? 365 TYR B OH  1 
ATOM   6152 N N   . THR C 1 196 ? -27.69  -2.457  -22.19  1   50.71  ? 366 THR B N   1 
ATOM   6153 C CA  . THR C 1 196 ? -26.979 -1.358  -22.841 1   52.14  ? 366 THR B CA  1 
ATOM   6154 C C   . THR C 1 196 ? -26.003 -1.907  -23.883 1   53.13  ? 366 THR B C   1 
ATOM   6155 O O   . THR C 1 196 ? -25.995 -1.437  -25.004 1   58.19  ? 366 THR B O   1 
ATOM   6156 C CB  . THR C 1 196 ? -26.252 -0.468  -21.822 1   50.34  ? 366 THR B CB  1 
ATOM   6157 O OG1 . THR C 1 196 ? -27.181 0.04    -20.864 1   52.47  ? 366 THR B OG1 1 
ATOM   6158 C CG2 . THR C 1 196 ? -25.502 0.688   -22.464 1   48.19  ? 366 THR B CG2 1 
ATOM   6159 N N   . VAL C 1 197 ? -25.189 -2.897  -23.504 1   52.07  ? 367 VAL B N   1 
ATOM   6160 C CA  . VAL C 1 197 ? -24.111 -3.399  -24.339 1   54.12  ? 367 VAL B CA  1 
ATOM   6161 C C   . VAL C 1 197 ? -24.618 -4.375  -25.399 1   54.6   ? 367 VAL B C   1 
ATOM   6162 O O   . VAL C 1 197 ? -24.182 -4.286  -26.547 1   55.2   ? 367 VAL B O   1 
ATOM   6163 C CB  . VAL C 1 197 ? -23.004 -4.058  -23.492 1   53.57  ? 367 VAL B CB  1 
ATOM   6164 C CG1 . VAL C 1 197 ? -21.969 -4.747  -24.373 1   50.82  ? 367 VAL B CG1 1 
ATOM   6165 C CG2 . VAL C 1 197 ? -22.353 -3.06   -22.542 1   50.55  ? 367 VAL B CG2 1 
ATOM   6166 N N   . THR C 1 198 ? -25.48  -5.328  -24.996 1   56.04  ? 368 THR B N   1 
ATOM   6167 C CA  . THR C 1 198 ? -25.867 -6.48   -25.823 1   55.95  ? 368 THR B CA  1 
ATOM   6168 C C   . THR C 1 198 ? -27.331 -6.448  -26.272 1   58.2   ? 368 THR B C   1 
ATOM   6169 O O   . THR C 1 198 ? -27.741 -7.299  -27.056 1   58.99  ? 368 THR B O   1 
ATOM   6170 C CB  . THR C 1 198 ? -25.646 -7.818  -25.11  1   53.68  ? 368 THR B CB  1 
ATOM   6171 O OG1 . THR C 1 198 ? -26.609 -7.978  -24.063 1   51.53  ? 368 THR B OG1 1 
ATOM   6172 C CG2 . THR C 1 198 ? -24.222 -7.989  -24.623 1   51     ? 368 THR B CG2 1 
ATOM   6173 N N   . GLY C 1 199 ? -28.162 -5.585  -25.683 1   59.62  ? 369 GLY B N   1 
ATOM   6174 C CA  . GLY C 1 199 ? -29.584 -5.62   -25.986 1   61.34  ? 369 GLY B CA  1 
ATOM   6175 C C   . GLY C 1 199 ? -30.33  -6.763  -25.287 1   65.38  ? 369 GLY B C   1 
ATOM   6176 O O   . GLY C 1 199 ? -31.523 -6.934  -25.499 1   69.93  ? 369 GLY B O   1 
ATOM   6177 N N   . GLN C 1 200 ? -29.647 -7.56   -24.459 1   64.8   ? 370 GLN B N   1 
ATOM   6178 C CA  . GLN C 1 200 ? -30.297 -8.693  -23.825 1   64.09  ? 370 GLN B CA  1 
ATOM   6179 C C   . GLN C 1 200 ? -30.863 -8.254  -22.48  1   59.63  ? 370 GLN B C   1 
ATOM   6180 O O   . GLN C 1 200 ? -30.518 -7.173  -22.009 1   57.59  ? 370 GLN B O   1 
ATOM   6181 C CB  . GLN C 1 200 ? -29.314 -9.845  -23.629 1   70.83  ? 370 GLN B CB  1 
ATOM   6182 C CG  . GLN C 1 200 ? -28.768 -10.423 -24.926 1   77.08  ? 370 GLN B CG  1 
ATOM   6183 C CD  . GLN C 1 200 ? -28.207 -11.813 -24.741 1   85.88  ? 370 GLN B CD  1 
ATOM   6184 O OE1 . GLN C 1 200 ? -28.648 -12.752 -25.416 1   98.39  ? 370 GLN B OE1 1 
ATOM   6185 N NE2 . GLN C 1 200 ? -27.242 -11.958 -23.837 1   77.04  ? 370 GLN B NE2 1 
ATOM   6186 N N   . SER C 1 201 ? -31.692 -9.118  -21.867 1   55.72  ? 371 SER B N   1 
ATOM   6187 C CA  . SER C 1 201 ? -32.336 -8.801  -20.597 1   53.36  ? 371 SER B CA  1 
ATOM   6188 C C   . SER C 1 201 ? -31.898 -9.749  -19.501 1   52.51  ? 371 SER B C   1 
ATOM   6189 O O   . SER C 1 201 ? -31.386 -10.822 -19.784 1   53.84  ? 371 SER B O   1 
ATOM   6190 C CB  . SER C 1 201 ? -33.819 -8.866  -20.693 1   52.52  ? 371 SER B CB  1 
ATOM   6191 O OG  . SER C 1 201 ? -34.267 -7.846  -21.565 1   54.43  ? 371 SER B OG  1 
ATOM   6192 N N   . TRP C 1 202 ? -32.185 -9.333  -18.259 1   54.71  ? 372 TRP B N   1 
ATOM   6193 C CA  . TRP C 1 202 ? -32.158 -10.159 -17.059 1   53.36  ? 372 TRP B CA  1 
ATOM   6194 C C   . TRP C 1 202 ? -32.574 -11.58  -17.417 1   52.98  ? 372 TRP B C   1 
ATOM   6195 O O   . TRP C 1 202 ? -33.694 -11.808 -17.866 1   55.44  ? 372 TRP B O   1 
ATOM   6196 C CB  . TRP C 1 202 ? -33.135 -9.589  -16.018 1   51.61  ? 372 TRP B CB  1 
ATOM   6197 C CG  . TRP C 1 202 ? -33.113 -10.257 -14.665 1   48.77  ? 372 TRP B CG  1 
ATOM   6198 C CD1 . TRP C 1 202 ? -34.106 -11.028 -14.147 1   50.9   ? 372 TRP B CD1 1 
ATOM   6199 C CD2 . TRP C 1 202 ? -32.072 -10.225 -13.666 1   48.07  ? 372 TRP B CD2 1 
ATOM   6200 N NE1 . TRP C 1 202 ? -33.779 -11.452 -12.891 1   50.36  ? 372 TRP B NE1 1 
ATOM   6201 C CE2 . TRP C 1 202 ? -32.533 -10.982 -12.57  1   48.46  ? 372 TRP B CE2 1 
ATOM   6202 C CE3 . TRP C 1 202 ? -30.805 -9.63   -13.584 1   48.06  ? 372 TRP B CE3 1 
ATOM   6203 C CZ2 . TRP C 1 202 ? -31.78  -11.159 -11.416 1   44.93  ? 372 TRP B CZ2 1 
ATOM   6204 C CZ3 . TRP C 1 202 ? -30.07  -9.784  -12.432 1   46.2   ? 372 TRP B CZ3 1 
ATOM   6205 C CH2 . TRP C 1 202 ? -30.548 -10.549 -11.37  1   46.2   ? 372 TRP B CH2 1 
ATOM   6206 N N   . PRO C 1 203 ? -31.665 -12.565 -17.272 1   48.66  ? 373 PRO B N   1 
ATOM   6207 C CA  . PRO C 1 203 ? -31.959 -13.943 -17.689 1   49.55  ? 373 PRO B CA  1 
ATOM   6208 C C   . PRO C 1 203 ? -32.767 -14.799 -16.718 1   49.15  ? 373 PRO B C   1 
ATOM   6209 O O   . PRO C 1 203 ? -32.62  -14.688 -15.489 1   48.27  ? 373 PRO B O   1 
ATOM   6210 C CB  . PRO C 1 203 ? -30.556 -14.521 -17.892 1   45.42  ? 373 PRO B CB  1 
ATOM   6211 C CG  . PRO C 1 203 ? -29.751 -13.815 -16.807 1   44.69  ? 373 PRO B CG  1 
ATOM   6212 C CD  . PRO C 1 203 ? -30.319 -12.381 -16.741 1   43.44  ? 373 PRO B CD  1 
ATOM   6213 N N   . GLU C 1 204 ? -33.525 -15.734 -17.299 1   50.68  ? 374 GLU B N   1 
ATOM   6214 C CA  . GLU C 1 204 ? -34.427 -16.566 -16.518 1   55.09  ? 374 GLU B CA  1 
ATOM   6215 C C   . GLU C 1 204 ? -33.623 -17.316 -15.455 1   53.35  ? 374 GLU B C   1 
ATOM   6216 O O   . GLU C 1 204 ? -34.11  -17.527 -14.34  1   51.79  ? 374 GLU B O   1 
ATOM   6217 C CB  . GLU C 1 204 ? -35.25  -17.46  -17.448 1   63.24  ? 374 GLU B CB  1 
ATOM   6218 C CG  . GLU C 1 204 ? -36.288 -18.33  -16.739 1   69.93  ? 374 GLU B CG  1 
ATOM   6219 C CD  . GLU C 1 204 ? -35.716 -19.589 -16.101 1   71.96  ? 374 GLU B CD  1 
ATOM   6220 O OE1 . GLU C 1 204 ? -34.658 -20.095 -16.537 1   66.11  ? 374 GLU B OE1 1 
ATOM   6221 O OE2 . GLU C 1 204 ? -36.358 -20.068 -15.15  1   79.67  ? 374 GLU B OE2 1 
ATOM   6222 N N   . SER C 1 205 ? -32.383 -17.692 -15.807 1   49.16  ? 375 SER B N   1 
ATOM   6223 C CA  . SER C 1 205 ? -31.539 -18.444 -14.903 1   46.89  ? 375 SER B CA  1 
ATOM   6224 C C   . SER C 1 205 ? -31.309 -17.63  -13.612 1   45.69  ? 375 SER B C   1 
ATOM   6225 O O   . SER C 1 205 ? -31.175 -18.186 -12.521 1   43.45  ? 375 SER B O   1 
ATOM   6226 C CB  . SER C 1 205 ? -30.244 -18.843 -15.61  1   49.28  ? 375 SER B CB  1 
ATOM   6227 O OG  . SER C 1 205 ? -29.219 -17.85  -15.53  1   49.33  ? 375 SER B OG  1 
ATOM   6228 N N   . LEU C 1 206 ? -31.287 -16.295 -13.722 1   44.76  ? 376 LEU B N   1 
ATOM   6229 C CA  . LEU C 1 206 ? -31.163 -15.449 -12.54  1   43.05  ? 376 LEU B CA  1 
ATOM   6230 C C   . LEU C 1 206 ? -32.526 -15.185 -11.891 1   44.4   ? 376 LEU B C   1 
ATOM   6231 O O   . LEU C 1 206 ? -32.579 -14.882 -10.695 1   43.13  ? 376 LEU B O   1 
ATOM   6232 C CB  . LEU C 1 206 ? -30.461 -14.147 -12.895 1   40.22  ? 376 LEU B CB  1 
ATOM   6233 C CG  . LEU C 1 206 ? -28.926 -14.224 -12.922 1   40.34  ? 376 LEU B CG  1 
ATOM   6234 C CD1 . LEU C 1 206 ? -28.317 -12.942 -13.468 1   38.78  ? 376 LEU B CD1 1 
ATOM   6235 C CD2 . LEU C 1 206 ? -28.373 -14.517 -11.535 1   37.3   ? 376 LEU B CD2 1 
ATOM   6236 N N   . VAL C 1 207 ? -33.616 -15.292 -12.665 1   42.18  ? 377 VAL B N   1 
ATOM   6237 C CA  . VAL C 1 207 ? -34.918 -15.408 -12.011 1   46.07  ? 377 VAL B CA  1 
ATOM   6238 C C   . VAL C 1 207 ? -34.912 -16.627 -11.068 1   45.83  ? 377 VAL B C   1 
ATOM   6239 O O   . VAL C 1 207 ? -35.366 -16.545 -9.936  1   45.1   ? 377 VAL B O   1 
ATOM   6240 C CB  . VAL C 1 207 ? -36.079 -15.482 -13.033 1   46.39  ? 377 VAL B CB  1 
ATOM   6241 C CG1 . VAL C 1 207 ? -37.41  -15.721 -12.343 1   47.77  ? 377 VAL B CG1 1 
ATOM   6242 C CG2 . VAL C 1 207 ? -36.166 -14.25  -13.922 1   43.37  ? 377 VAL B CG2 1 
ATOM   6243 N N   . GLN C 1 208 ? -34.381 -17.77  -11.529 1   46.79  ? 378 GLN B N   1 
ATOM   6244 C CA  . GLN C 1 208 ? -34.358 -18.992 -10.732 1   47.77  ? 378 GLN B CA  1 
ATOM   6245 C C   . GLN C 1 208 ? -33.562 -18.736 -9.449  1   48.84  ? 378 GLN B C   1 
ATOM   6246 O O   . GLN C 1 208 ? -33.993 -19.116 -8.36   1   51.61  ? 378 GLN B O   1 
ATOM   6247 C CB  . GLN C 1 208 ? -33.762 -20.183 -11.501 1   48.35  ? 378 GLN B CB  1 
ATOM   6248 C CG  . GLN C 1 208 ? -34.539 -20.674 -12.718 1   50.42  ? 378 GLN B CG  1 
ATOM   6249 C CD  . GLN C 1 208 ? -35.88  -21.292 -12.352 1   57.37  ? 378 GLN B CD  1 
ATOM   6250 O OE1 . GLN C 1 208 ? -36.888 -21.146 -13.07  1   56.69  ? 378 GLN B OE1 1 
ATOM   6251 N NE2 . GLN C 1 208 ? -35.904 -21.996 -11.221 1   57.19  ? 378 GLN B NE2 1 
ATOM   6252 N N   . LYS C 1 209 ? -32.405 -18.064 -9.582  1   44.81  ? 379 LYS B N   1 
ATOM   6253 C CA  . LYS C 1 209 ? -31.482 -17.957 -8.471  1   43.88  ? 379 LYS B CA  1 
ATOM   6254 C C   . LYS C 1 209 ? -32.033 -16.973 -7.434  1   42.76  ? 379 LYS B C   1 
ATOM   6255 O O   . LYS C 1 209 ? -32.011 -17.25  -6.223  1   41.4   ? 379 LYS B O   1 
ATOM   6256 C CB  . LYS C 1 209 ? -30.089 -17.594 -9.006  1   43.96  ? 379 LYS B CB  1 
ATOM   6257 C CG  . LYS C 1 209 ? -29.042 -17.312 -7.927  1   43.88  ? 379 LYS B CG  1 
ATOM   6258 C CD  . LYS C 1 209 ? -27.894 -16.42  -8.406  1   46.69  ? 379 LYS B CD  1 
ATOM   6259 C CE  . LYS C 1 209 ? -26.713 -16.42  -7.429  1   49.46  ? 379 LYS B CE  1 
ATOM   6260 N NZ  . LYS C 1 209 ? -26.128 -17.754 -7.185  1   51.41  ? 379 LYS B NZ  1 
ATOM   6261 N N   . THR C 1 210 ? -32.555 -15.836 -7.919  1   42.97  ? 380 THR B N   1 
ATOM   6262 C CA  . THR C 1 210 ? -32.778 -14.689 -7.036  1   44.33  ? 380 THR B CA  1 
ATOM   6263 C C   . THR C 1 210 ? -34.253 -14.546 -6.658  1   44.84  ? 380 THR B C   1 
ATOM   6264 O O   . THR C 1 210 ? -34.543 -13.945 -5.626  1   46.43  ? 380 THR B O   1 
ATOM   6265 C CB  . THR C 1 210 ? -32.304 -13.387 -7.683  1   42.76  ? 380 THR B CB  1 
ATOM   6266 O OG1 . THR C 1 210 ? -33.109 -13.137 -8.841  1   42.46  ? 380 THR B OG1 1 
ATOM   6267 C CG2 . THR C 1 210 ? -30.829 -13.426 -8.037  1   41.92  ? 380 THR B CG2 1 
ATOM   6268 N N   . GLY C 1 211 ? -35.158 -15.043 -7.507  1   42.84  ? 381 GLY B N   1 
ATOM   6269 C CA  . GLY C 1 211 ? -36.59  -14.783 -7.357  1   44.66  ? 381 GLY B CA  1 
ATOM   6270 C C   . GLY C 1 211 ? -37.002 -13.423 -7.934  1   44.13  ? 381 GLY B C   1 
ATOM   6271 O O   . GLY C 1 211 ? -38.169 -13.108 -7.999  1   44.94  ? 381 GLY B O   1 
ATOM   6272 N N   . TYR C 1 212 ? -36.038 -12.603 -8.361  1   45.07  ? 382 TYR B N   1 
ATOM   6273 C CA  . TYR C 1 212 ? -36.344 -11.284 -8.892  1   45.14  ? 382 TYR B CA  1 
ATOM   6274 C C   . TYR C 1 212 ? -36.636 -11.384 -10.391 1   46.04  ? 382 TYR B C   1 
ATOM   6275 O O   . TYR C 1 212 ? -36.003 -12.173 -11.108 1   45.12  ? 382 TYR B O   1 
ATOM   6276 C CB  . TYR C 1 212 ? -35.117 -10.396 -8.698  1   43.49  ? 382 TYR B CB  1 
ATOM   6277 C CG  . TYR C 1 212 ? -34.63  -10.173 -7.273  1   44.7   ? 382 TYR B CG  1 
ATOM   6278 C CD1 . TYR C 1 212 ? -35.506 -10.222 -6.176  1   45.55  ? 382 TYR B CD1 1 
ATOM   6279 C CD2 . TYR C 1 212 ? -33.304 -9.829  -7.035  1   41.53  ? 382 TYR B CD2 1 
ATOM   6280 C CE1 . TYR C 1 212 ? -35.064 -9.957  -4.89   1   42.74  ? 382 TYR B CE1 1 
ATOM   6281 C CE2 . TYR C 1 212 ? -32.856 -9.569  -5.751  1   41.2   ? 382 TYR B CE2 1 
ATOM   6282 C CZ  . TYR C 1 212 ? -33.725 -9.637  -4.674  1   42.27  ? 382 TYR B CZ  1 
ATOM   6283 O OH  . TYR C 1 212 ? -33.198 -9.372  -3.422  1   40.34  ? 382 TYR B OH  1 
ATOM   6284 N N   . THR C 1 213 ? -37.642 -10.61  -10.837 1   46.74  ? 383 THR B N   1 
ATOM   6285 C CA  . THR C 1 213 ? -38.028 -10.476 -12.239 1   48.43  ? 383 THR B CA  1 
ATOM   6286 C C   . THR C 1 213 ? -37.864 -9.016  -12.626 1   49.53  ? 383 THR B C   1 
ATOM   6287 O O   . THR C 1 213 ? -37.722 -8.168  -11.751 1   51.23  ? 383 THR B O   1 
ATOM   6288 C CB  . THR C 1 213 ? -39.483 -10.877 -12.478 1   49.56  ? 383 THR B CB  1 
ATOM   6289 O OG1 . THR C 1 213 ? -40.243 -9.855  -11.832 1   50.24  ? 383 THR B OG1 1 
ATOM   6290 C CG2 . THR C 1 213 ? -39.804 -12.286 -12.015 1   48.32  ? 383 THR B CG2 1 
ATOM   6291 N N   . LEU C 1 214 ? -37.927 -8.715  -13.921 1   50.29  ? 384 LEU B N   1 
ATOM   6292 C CA  . LEU C 1 214 ? -37.932 -7.32   -14.32  1   54.56  ? 384 LEU B CA  1 
ATOM   6293 C C   . LEU C 1 214 ? -39.061 -6.566  -13.631 1   56.06  ? 384 LEU B C   1 
ATOM   6294 O O   . LEU C 1 214 ? -38.916 -5.377  -13.38  1   59.12  ? 384 LEU B O   1 
ATOM   6295 C CB  . LEU C 1 214 ? -38.066 -7.181  -15.831 1   58.75  ? 384 LEU B CB  1 
ATOM   6296 C CG  . LEU C 1 214 ? -36.827 -7.587  -16.622 1   59.22  ? 384 LEU B CG  1 
ATOM   6297 C CD1 . LEU C 1 214 ? -37.042 -7.262  -18.079 1   62.16  ? 384 LEU B CD1 1 
ATOM   6298 C CD2 . LEU C 1 214 ? -35.657 -6.816  -16.062 1   58.05  ? 384 LEU B CD2 1 
ATOM   6299 N N   . GLU C 1 215 ? -40.183 -7.237  -13.349 1   59.01  ? 385 GLU B N   1 
ATOM   6300 C CA  . GLU C 1 215 ? -41.272 -6.59   -12.617 1   59.61  ? 385 GLU B CA  1 
ATOM   6301 C C   . GLU C 1 215 ? -40.821 -6.17   -11.206 1   55.61  ? 385 GLU B C   1 
ATOM   6302 O O   . GLU C 1 215 ? -41.078 -5.047  -10.784 1   54.03  ? 385 GLU B O   1 
ATOM   6303 C CB  . GLU C 1 215 ? -42.523 -7.456  -12.682 1   62.68  ? 385 GLU B CB  1 
ATOM   6304 C CG  . GLU C 1 215 ? -43.469 -7.185  -11.522 1   76.48  ? 385 GLU B CG  1 
ATOM   6305 C CD  . GLU C 1 215 ? -44.582 -8.215  -11.319 1   91.28  ? 385 GLU B CD  1 
ATOM   6306 O OE1 . GLU C 1 215 ? -45.587 -8.188  -12.067 1   82.32  ? 385 GLU B OE1 1 
ATOM   6307 O OE2 . GLU C 1 215 ? -44.421 -9.069  -10.411 1   96.27  ? 385 GLU B OE2 1 
ATOM   6308 N N   . THR C 1 216 ? -40.111 -7.034  -10.474 1   51.26  ? 386 THR B N   1 
ATOM   6309 C CA  . THR C 1 216 ? -39.748 -6.653  -9.124  1   53.14  ? 386 THR B CA  1 
ATOM   6310 C C   . THR C 1 216 ? -38.613 -5.62   -9.141  1   54.75  ? 386 THR B C   1 
ATOM   6311 O O   . THR C 1 216 ? -38.572 -4.747  -8.276  1   56.88  ? 386 THR B O   1 
ATOM   6312 C CB  . THR C 1 216 ? -39.522 -7.867  -8.209  1   54.59  ? 386 THR B CB  1 
ATOM   6313 O OG1 . THR C 1 216 ? -38.392 -8.636  -8.6    1   52.18  ? 386 THR B OG1 1 
ATOM   6314 C CG2 . THR C 1 216 ? -40.747 -8.765  -8.099  1   56.28  ? 386 THR B CG2 1 
ATOM   6315 N N   . LEU C 1 217 ? -37.749 -5.647  -10.167 1   52.42  ? 387 LEU B N   1 
ATOM   6316 C CA  . LEU C 1 217 ? -36.645 -4.702  -10.272 1   49.84  ? 387 LEU B CA  1 
ATOM   6317 C C   . LEU C 1 217 ? -37.096 -3.358  -10.853 1   49.86  ? 387 LEU B C   1 
ATOM   6318 O O   . LEU C 1 217 ? -36.345 -2.384  -10.817 1   49.2   ? 387 LEU B O   1 
ATOM   6319 C CB  . LEU C 1 217 ? -35.516 -5.298  -11.115 1   48.65  ? 387 LEU B CB  1 
ATOM   6320 C CG  . LEU C 1 217 ? -34.978 -6.661  -10.668 1   48.33  ? 387 LEU B CG  1 
ATOM   6321 C CD1 . LEU C 1 217 ? -33.878 -7.121  -11.61  1   47.63  ? 387 LEU B CD1 1 
ATOM   6322 C CD2 . LEU C 1 217 ? -34.486 -6.587  -9.233  1   45.71  ? 387 LEU B CD2 1 
ATOM   6323 N N   . LYS C 1 218 ? -38.301 -3.299  -11.412 1   49.42  ? 388 LYS B N   1 
ATOM   6324 C CA  . LYS C 1 218 ? -38.741 -2.14   -12.173 1   52.32  ? 388 LYS B CA  1 
ATOM   6325 C C   . LYS C 1 218 ? -38.503 -0.822  -11.422 1   54.15  ? 388 LYS B C   1 
ATOM   6326 O O   . LYS C 1 218 ? -38.056 0.145   -12.03  1   57.64  ? 388 LYS B O   1 
ATOM   6327 C CB  . LYS C 1 218 ? -40.191 -2.316  -12.63  1   52.75  ? 388 LYS B CB  1 
ATOM   6328 C CG  . LYS C 1 218 ? -40.668 -1.322  -13.683 1   57.73  ? 388 LYS B CG  1 
ATOM   6329 C CD  . LYS C 1 218 ? -42.175 -1.257  -13.902 1   56.35  ? 388 LYS B CD  1 
ATOM   6330 C CE  . LYS C 1 218 ? -42.536 -0.631  -15.23  1   62.06  ? 388 LYS B CE  1 
ATOM   6331 N NZ  . LYS C 1 218 ? -43.991 -0.506  -15.477 1   62.2   ? 388 LYS B NZ  1 
ATOM   6332 N N   . PRO C 1 219 ? -38.871 -0.657  -10.134 1   54.54  ? 389 PRO B N   1 
ATOM   6333 C CA  . PRO C 1 219 ? -38.649 0.627   -9.463  1   54.47  ? 389 PRO B CA  1 
ATOM   6334 C C   . PRO C 1 219 ? -37.183 1.055   -9.434  1   50.82  ? 389 PRO B C   1 
ATOM   6335 O O   . PRO C 1 219 ? -36.829 2.178   -9.768  1   51.06  ? 389 PRO B O   1 
ATOM   6336 C CB  . PRO C 1 219 ? -39.234 0.391   -8.042  1   53.29  ? 389 PRO B CB  1 
ATOM   6337 C CG  . PRO C 1 219 ? -40.26  -0.695  -8.253  1   52.77  ? 389 PRO B CG  1 
ATOM   6338 C CD  . PRO C 1 219 ? -39.628 -1.607  -9.3    1   54.94  ? 389 PRO B CD  1 
ATOM   6339 N N   . CYS C 1 220 ? -36.334 0.141   -8.994  1   50.92  ? 390 CYS B N   1 
ATOM   6340 C CA  . CYS C 1 220 ? -34.906 0.383   -8.889  1   49.29  ? 390 CYS B CA  1 
ATOM   6341 C C   . CYS C 1 220 ? -34.281 0.725   -10.25  1   50.02  ? 390 CYS B C   1 
ATOM   6342 O O   . CYS C 1 220 ? -33.541 1.703   -10.401 1   49.43  ? 390 CYS B O   1 
ATOM   6343 C CB  . CYS C 1 220 ? -34.255 -0.873  -8.35   1   46.5   ? 390 CYS B CB  1 
ATOM   6344 S SG  . CYS C 1 220 ? -32.526 -0.563  -7.952  1   46.43  ? 390 CYS B SG  1 
ATOM   6345 N N   . LEU C 1 221 ? -34.639 -0.077  -11.253 1   48.38  ? 391 LEU B N   1 
ATOM   6346 C CA  . LEU C 1 221 ? -34.207 0.068   -12.63  1   48.89  ? 391 LEU B CA  1 
ATOM   6347 C C   . LEU C 1 221 ? -34.561 1.441   -13.194 1   49.54  ? 391 LEU B C   1 
ATOM   6348 O O   . LEU C 1 221 ? -33.783 2.013   -13.958 1   46.92  ? 391 LEU B O   1 
ATOM   6349 C CB  . LEU C 1 221 ? -34.967 -1.042  -13.353 1   53.24  ? 391 LEU B CB  1 
ATOM   6350 C CG  . LEU C 1 221 ? -34.319 -1.643  -14.599 1   56.01  ? 391 LEU B CG  1 
ATOM   6351 C CD1 . LEU C 1 221 ? -32.796 -1.7    -14.496 1   53.19  ? 391 LEU B CD1 1 
ATOM   6352 C CD2 . LEU C 1 221 ? -34.904 -3.046  -14.705 1   56.31  ? 391 LEU B CD2 1 
ATOM   6353 N N   . LEU C 1 222 ? -35.741 1.961   -12.826 1   49.5   ? 392 LEU B N   1 
ATOM   6354 C CA  . LEU C 1 222 ? -36.186 3.253   -13.319 1   53.49  ? 392 LEU B CA  1 
ATOM   6355 C C   . LEU C 1 222 ? -35.326 4.363   -12.716 1   53.49  ? 392 LEU B C   1 
ATOM   6356 O O   . LEU C 1 222 ? -34.959 5.307   -13.408 1   54.81  ? 392 LEU B O   1 
ATOM   6357 C CB  . LEU C 1 222 ? -37.668 3.484   -13.014 1   56.63  ? 392 LEU B CB  1 
ATOM   6358 C CG  . LEU C 1 222 ? -38.682 2.783   -13.916 1   59.73  ? 392 LEU B CG  1 
ATOM   6359 C CD1 . LEU C 1 222 ? -40.04  3.433   -13.73  1   59.66  ? 392 LEU B CD1 1 
ATOM   6360 C CD2 . LEU C 1 222 ? -38.263 2.947   -15.347 1   64.14  ? 392 LEU B CD2 1 
ATOM   6361 N N   . ASP C 1 223 ? -35.025 4.253   -11.418 1   52.5   ? 393 ASP B N   1 
ATOM   6362 C CA  . ASP C 1 223 ? -34.117 5.184   -10.755 1   52.74  ? 393 ASP B CA  1 
ATOM   6363 C C   . ASP C 1 223 ? -32.706 5.109   -11.345 1   50.52  ? 393 ASP B C   1 
ATOM   6364 O O   . ASP C 1 223 ? -32.073 6.14    -11.571 1   50.17  ? 393 ASP B O   1 
ATOM   6365 C CB  . ASP C 1 223 ? -34.074 4.999   -9.24   1   51.05  ? 393 ASP B CB  1 
ATOM   6366 C CG  . ASP C 1 223 ? -35.335 5.423   -8.5    1   51.07  ? 393 ASP B CG  1 
ATOM   6367 O OD1 . ASP C 1 223 ? -35.958 6.39    -8.96   1   55.09  ? 393 ASP B OD1 1 
ATOM   6368 O OD2 . ASP C 1 223 ? -35.676 4.786   -7.472  1   52.13  ? 393 ASP B OD2 1 
ATOM   6369 N N   . LEU C 1 224 ? -32.222 3.888   -11.585 1   47.27  ? 394 LEU B N   1 
ATOM   6370 C CA  . LEU C 1 224 ? -30.835 3.684   -11.97  1   48.38  ? 394 LEU B CA  1 
ATOM   6371 C C   . LEU C 1 224 ? -30.64  4.175   -13.405 1   50.24  ? 394 LEU B C   1 
ATOM   6372 O O   . LEU C 1 224 ? -29.565 4.667   -13.771 1   49.51  ? 394 LEU B O   1 
ATOM   6373 C CB  . LEU C 1 224 ? -30.453 2.215   -11.803 1   45.5   ? 394 LEU B CB  1 
ATOM   6374 C CG  . LEU C 1 224 ? -28.951 1.904   -11.841 1   45.88  ? 394 LEU B CG  1 
ATOM   6375 C CD1 . LEU C 1 224 ? -28.231 2.546   -10.691 1   44.61  ? 394 LEU B CD1 1 
ATOM   6376 C CD2 . LEU C 1 224 ? -28.642 0.42    -11.864 1   42.71  ? 394 LEU B CD2 1 
ATOM   6377 N N   . HIS C 1 225 ? -31.714 4.06    -14.194 1   49     ? 395 HIS B N   1 
ATOM   6378 C CA  . HIS C 1 225 ? -31.72  4.472   -15.582 1   50.24  ? 395 HIS B CA  1 
ATOM   6379 C C   . HIS C 1 225 ? -31.656 5.997   -15.639 1   53.3   ? 395 HIS B C   1 
ATOM   6380 O O   . HIS C 1 225 ? -30.997 6.545   -16.504 1   56.46  ? 395 HIS B O   1 
ATOM   6381 C CB  . HIS C 1 225 ? -32.931 3.865   -16.295 1   48.49  ? 395 HIS B CB  1 
ATOM   6382 C CG  . HIS C 1 225 ? -33.057 4.299   -17.687 1   51.21  ? 395 HIS B CG  1 
ATOM   6383 N ND1 . HIS C 1 225 ? -31.98  4.222   -18.54  1   53.34  ? 395 HIS B ND1 1 
ATOM   6384 C CD2 . HIS C 1 225 ? -34.077 4.81    -18.409 1   57.45  ? 395 HIS B CD2 1 
ATOM   6385 C CE1 . HIS C 1 225 ? -32.342 4.662   -19.743 1   56.06  ? 395 HIS B CE1 1 
ATOM   6386 N NE2 . HIS C 1 225 ? -33.62  5.024   -19.696 1   57.26  ? 395 HIS B NE2 1 
ATOM   6387 N N   . GLN C 1 226 ? -32.351 6.685   -14.729 1   54.94  ? 396 GLN B N   1 
ATOM   6388 C CA  . GLN C 1 226 ? -32.259 8.129   -14.611 1   58.41  ? 396 GLN B CA  1 
ATOM   6389 C C   . GLN C 1 226 ? -30.858 8.516   -14.139 1   56.9   ? 396 GLN B C   1 
ATOM   6390 O O   . GLN C 1 226 ? -30.267 9.479   -14.641 1   60.68  ? 396 GLN B O   1 
ATOM   6391 C CB  . GLN C 1 226 ? -33.276 8.689   -13.616 1   64.1   ? 396 GLN B CB  1 
ATOM   6392 C CG  . GLN C 1 226 ? -34.493 9.363   -14.248 1   79.85  ? 396 GLN B CG  1 
ATOM   6393 C CD  . GLN C 1 226 ? -35.274 10.213  -13.258 1   93.7   ? 396 GLN B CD  1 
ATOM   6394 O OE1 . GLN C 1 226 ? -36.511 10.269  -13.278 1   108.1  ? 396 GLN B OE1 1 
ATOM   6395 N NE2 . GLN C 1 226 ? -34.56  10.903  -12.378 1   95.05  ? 396 GLN B NE2 1 
ATOM   6396 N N   . THR C 1 227 ? -30.333 7.77    -13.164 1   51.25  ? 397 THR B N   1 
ATOM   6397 C CA  . THR C 1 227 ? -29.038 8.121   -12.619 1   49.68  ? 397 THR B CA  1 
ATOM   6398 C C   . THR C 1 227 ? -28.005 8.035   -13.742 1   49.51  ? 397 THR B C   1 
ATOM   6399 O O   . THR C 1 227 ? -27.249 8.974   -13.947 1   51.21  ? 397 THR B O   1 
ATOM   6400 C CB  . THR C 1 227 ? -28.71  7.283   -11.38  1   48.14  ? 397 THR B CB  1 
ATOM   6401 O OG1 . THR C 1 227 ? -29.506 7.756   -10.285 1   44.02  ? 397 THR B OG1 1 
ATOM   6402 C CG2 . THR C 1 227 ? -27.232 7.376   -11.025 1   46.65  ? 397 THR B CG2 1 
ATOM   6403 N N   . TYR C 1 228 ? -28.036 6.949   -14.516 1   49.08  ? 398 TYR B N   1 
ATOM   6404 C CA  . TYR C 1 228 ? -27.171 6.773   -15.676 1   50.34  ? 398 TYR B CA  1 
ATOM   6405 C C   . TYR C 1 228 ? -27.323 7.923   -16.685 1   56     ? 398 TYR B C   1 
ATOM   6406 O O   . TYR C 1 228 ? -26.312 8.474   -17.132 1   55.89  ? 398 TYR B O   1 
ATOM   6407 C CB  . TYR C 1 228 ? -27.487 5.399   -16.261 1   47.81  ? 398 TYR B CB  1 
ATOM   6408 C CG  . TYR C 1 228 ? -26.521 4.868   -17.3   1   49.69  ? 398 TYR B CG  1 
ATOM   6409 C CD1 . TYR C 1 228 ? -25.265 5.436   -17.505 1   51.03  ? 398 TYR B CD1 1 
ATOM   6410 C CD2 . TYR C 1 228 ? -26.864 3.754   -18.039 1   50.86  ? 398 TYR B CD2 1 
ATOM   6411 C CE1 . TYR C 1 228 ? -24.393 4.921   -18.447 1   51.76  ? 398 TYR B CE1 1 
ATOM   6412 C CE2 . TYR C 1 228 ? -25.996 3.222   -18.971 1   53.13  ? 398 TYR B CE2 1 
ATOM   6413 C CZ  . TYR C 1 228 ? -24.761 3.809   -19.181 1   54.7   ? 398 TYR B CZ  1 
ATOM   6414 O OH  . TYR C 1 228 ? -23.95  3.249   -20.135 1   56.57  ? 398 TYR B OH  1 
ATOM   6415 N N   . LEU C 1 229 ? -28.569 8.34    -16.996 1   53.87  ? 399 LEU B N   1 
ATOM   6416 C CA  . LEU C 1 229 ? -28.8   9.398   -17.964 1   54.25  ? 399 LEU B CA  1 
ATOM   6417 C C   . LEU C 1 229 ? -28.256 10.723  -17.444 1   55.4   ? 399 LEU B C   1 
ATOM   6418 O O   . LEU C 1 229 ? -27.704 11.491  -18.22  1   56.7   ? 399 LEU B O   1 
ATOM   6419 C CB  . LEU C 1 229 ? -30.273 9.525   -18.329 1   56.18  ? 399 LEU B CB  1 
ATOM   6420 C CG  . LEU C 1 229 ? -30.859 8.456   -19.268 1   57.91  ? 399 LEU B CG  1 
ATOM   6421 C CD1 . LEU C 1 229 ? -32.386 8.529   -19.294 1   57.48  ? 399 LEU B CD1 1 
ATOM   6422 C CD2 . LEU C 1 229 ? -30.341 8.589   -20.694 1   60.77  ? 399 LEU B CD2 1 
ATOM   6423 N N   . ARG C 1 230 ? -28.422 11.007  -16.146 1   57.03  ? 400 ARG B N   1 
ATOM   6424 C CA  . ARG C 1 230 ? -28.016 12.3    -15.603 1   62.02  ? 400 ARG B CA  1 
ATOM   6425 C C   . ARG C 1 230 ? -26.523 12.335  -15.265 1   58.04  ? 400 ARG B C   1 
ATOM   6426 O O   . ARG C 1 230 ? -26.02  13.389  -14.884 1   56.17  ? 400 ARG B O   1 
ATOM   6427 C CB  . ARG C 1 230 ? -28.765 12.685  -14.322 1   68.25  ? 400 ARG B CB  1 
ATOM   6428 C CG  . ARG C 1 230 ? -30.188 13.186  -14.521 1   87.64  ? 400 ARG B CG  1 
ATOM   6429 C CD  . ARG C 1 230 ? -31.057 13.025  -13.269 1   101.4  ? 400 ARG B CD  1 
ATOM   6430 N NE  . ARG C 1 230 ? -32.392 13.629  -13.374 1   116.78 ? 400 ARG B NE  1 
ATOM   6431 C CZ  . ARG C 1 230 ? -33.387 13.284  -14.198 1   115.86 ? 400 ARG B CZ  1 
ATOM   6432 N NH1 . ARG C 1 230 ? -33.256 12.259  -15.031 1   113.37 ? 400 ARG B NH1 1 
ATOM   6433 N NH2 . ARG C 1 230 ? -34.524 13.965  -14.165 1   103.49 ? 400 ARG B NH2 1 
ATOM   6434 N N   . ALA C 1 231 ? -25.819 11.203  -15.389 1   52.91  ? 401 ALA B N   1 
ATOM   6435 C CA  . ALA C 1 231 ? -24.541 11.079  -14.695 1   54.14  ? 401 ALA B CA  1 
ATOM   6436 C C   . ALA C 1 231 ? -23.554 12.178  -15.111 1   54.63  ? 401 ALA B C   1 
ATOM   6437 O O   . ALA C 1 231 ? -22.793 12.662  -14.276 1   54.72  ? 401 ALA B O   1 
ATOM   6438 C CB  . ALA C 1 231 ? -23.948 9.681   -14.823 1   50.95  ? 401 ALA B CB  1 
ATOM   6439 N N   . PRO C 1 232 ? -23.478 12.581  -16.402 1   55.01  ? 402 PRO B N   1 
ATOM   6440 C CA  . PRO C 1 232 ? -22.597 13.684  -16.799 1   57.56  ? 402 PRO B CA  1 
ATOM   6441 C C   . PRO C 1 232 ? -22.878 15.041  -16.151 1   58.98  ? 402 PRO B C   1 
ATOM   6442 O O   . PRO C 1 232 ? -22.03  15.926  -16.185 1   58.62  ? 402 PRO B O   1 
ATOM   6443 C CB  . PRO C 1 232 ? -22.758 13.77   -18.338 1   57.44  ? 402 PRO B CB  1 
ATOM   6444 C CG  . PRO C 1 232 ? -23.357 12.443  -18.744 1   55.69  ? 402 PRO B CG  1 
ATOM   6445 C CD  . PRO C 1 232 ? -24.149 11.955  -17.551 1   54.42  ? 402 PRO B CD  1 
ATOM   6446 N N   . GLN C 1 233 ? -24.076 15.212  -15.587 1   61.08  ? 403 GLN B N   1 
ATOM   6447 C CA  . GLN C 1 233 ? -24.497 16.483  -15.008 1   64.25  ? 403 GLN B CA  1 
ATOM   6448 C C   . GLN C 1 233 ? -24.398 16.46   -13.48  1   60.66  ? 403 GLN B C   1 
ATOM   6449 O O   . GLN C 1 233 ? -24.527 17.499  -12.844 1   61.31  ? 403 GLN B O   1 
ATOM   6450 C CB  . GLN C 1 233 ? -25.943 16.82   -15.387 1   70.66  ? 403 GLN B CB  1 
ATOM   6451 C CG  . GLN C 1 233 ? -26.104 17.66   -16.653 1   80.22  ? 403 GLN B CG  1 
ATOM   6452 C CD  . GLN C 1 233 ? -25.574 17.016  -17.921 1   82.17  ? 403 GLN B CD  1 
ATOM   6453 O OE1 . GLN C 1 233 ? -24.775 17.606  -18.658 1   87.26  ? 403 GLN B OE1 1 
ATOM   6454 N NE2 . GLN C 1 233 ? -26.028 15.803  -18.203 1   77.2   ? 403 GLN B NE2 1 
ATOM   6455 N N   . HIS C 1 234 ? -24.212 15.272  -12.889 1   57.68  ? 404 HIS B N   1 
ATOM   6456 C CA  . HIS C 1 234 ? -24.141 15.162  -11.441 1   54.6   ? 404 HIS B CA  1 
ATOM   6457 C C   . HIS C 1 234 ? -22.996 16.055  -10.969 1   55.1   ? 404 HIS B C   1 
ATOM   6458 O O   . HIS C 1 234 ? -21.988 16.187  -11.65  1   55.44  ? 404 HIS B O   1 
ATOM   6459 C CB  . HIS C 1 234 ? -23.892 13.704  -11.053 1   51.03  ? 404 HIS B CB  1 
ATOM   6460 C CG  . HIS C 1 234 ? -24.292 13.354  -9.664  1   52.43  ? 404 HIS B CG  1 
ATOM   6461 N ND1 . HIS C 1 234 ? -23.586 13.754  -8.546  1   50.25  ? 404 HIS B ND1 1 
ATOM   6462 C CD2 . HIS C 1 234 ? -25.323 12.592  -9.218  1   49.99  ? 404 HIS B CD2 1 
ATOM   6463 C CE1 . HIS C 1 234 ? -24.188 13.264  -7.466  1   51.32  ? 404 HIS B CE1 1 
ATOM   6464 N NE2 . HIS C 1 234 ? -25.23  12.542  -7.851  1   51.19  ? 404 HIS B NE2 1 
ATOM   6465 N N   . ALA C 1 235 ? -23.161 16.683  -9.807  1   56.2   ? 405 ALA B N   1 
ATOM   6466 C CA  . ALA C 1 235 ? -22.096 17.44   -9.15   1   54.73  ? 405 ALA B CA  1 
ATOM   6467 C C   . ALA C 1 235 ? -20.866 16.569  -8.821  1   53.45  ? 405 ALA B C   1 
ATOM   6468 O O   . ALA C 1 235 ? -19.744 17.063  -8.805  1   54.72  ? 405 ALA B O   1 
ATOM   6469 C CB  . ALA C 1 235 ? -22.684 18.095  -7.91   1   50.95  ? 405 ALA B CB  1 
ATOM   6470 N N   . GLN C 1 236 ? -21.062 15.271  -8.541  1   49.75  ? 406 GLN B N   1 
ATOM   6471 C CA  . GLN C 1 236 ? -19.956 14.351  -8.303  1   48.91  ? 406 GLN B CA  1 
ATOM   6472 C C   . GLN C 1 236 ? -19.583 13.586  -9.574  1   50.92  ? 406 GLN B C   1 
ATOM   6473 O O   . GLN C 1 236 ? -20.447 12.973  -10.216 1   51.76  ? 406 GLN B O   1 
ATOM   6474 C CB  . GLN C 1 236 ? -20.32  13.381  -7.185  1   47.16  ? 406 GLN B CB  1 
ATOM   6475 C CG  . GLN C 1 236 ? -20.179 13.98   -5.79   1   50.46  ? 406 GLN B CG  1 
ATOM   6476 C CD  . GLN C 1 236 ? -21.057 15.19   -5.519  1   55.01  ? 406 GLN B CD  1 
ATOM   6477 O OE1 . GLN C 1 236 ? -22.282 15.167  -5.683  1   58.82  ? 406 GLN B OE1 1 
ATOM   6478 N NE2 . GLN C 1 236 ? -20.434 16.271  -5.07   1   55.11  ? 406 GLN B NE2 1 
ATOM   6479 N N   . GLN C 1 237 ? -18.275 13.593  -9.901  1   50.17  ? 407 GLN B N   1 
ATOM   6480 C CA  . GLN C 1 237 ? -17.783 13.092  -11.18  1   50.41  ? 407 GLN B CA  1 
ATOM   6481 C C   . GLN C 1 237 ? -16.658 12.063  -11.009 1   49.15  ? 407 GLN B C   1 
ATOM   6482 O O   . GLN C 1 237 ? -16.15  11.525  -11.994 1   48.3   ? 407 GLN B O   1 
ATOM   6483 C CB  . GLN C 1 237 ? -17.303 14.274  -12.019 1   50.38  ? 407 GLN B CB  1 
ATOM   6484 C CG  . GLN C 1 237 ? -18.421 15.12   -12.611 1   51.58  ? 407 GLN B CG  1 
ATOM   6485 C CD  . GLN C 1 237 ? -19.272 14.321  -13.574 1   53.92  ? 407 GLN B CD  1 
ATOM   6486 O OE1 . GLN C 1 237 ? -18.749 13.517  -14.345 1   55.32  ? 407 GLN B OE1 1 
ATOM   6487 N NE2 . GLN C 1 237 ? -20.59  14.465  -13.514 1   52.28  ? 407 GLN B NE2 1 
ATOM   6488 N N   . SER C 1 238 ? -16.297 11.752  -9.764  1   46.72  ? 408 SER B N   1 
ATOM   6489 C CA  . SER C 1 238 ? -15.102 10.942  -9.545  1   48.65  ? 408 SER B CA  1 
ATOM   6490 C C   . SER C 1 238 ? -15.247 9.539   -10.148 1   47.34  ? 408 SER B C   1 
ATOM   6491 O O   . SER C 1 238 ? -14.273 8.974   -10.659 1   47.21  ? 408 SER B O   1 
ATOM   6492 C CB  . SER C 1 238 ? -14.742 10.85   -8.076  1   45.9   ? 408 SER B CB  1 
ATOM   6493 O OG  . SER C 1 238 ? -14.236 12.097  -7.623  1   47.48  ? 408 SER B OG  1 
ATOM   6494 N N   . ILE C 1 239 ? -16.461 8.988   -10.05  1   42.86  ? 409 ILE B N   1 
ATOM   6495 C CA  . ILE C 1 239 ? -16.759 7.658   -10.552 1   41.97  ? 409 ILE B CA  1 
ATOM   6496 C C   . ILE C 1 239 ? -16.727 7.636   -12.077 1   42.25  ? 409 ILE B C   1 
ATOM   6497 O O   . ILE C 1 239 ? -16.12  6.739   -12.664 1   43.37  ? 409 ILE B O   1 
ATOM   6498 C CB  . ILE C 1 239 ? -18.078 7.106   -9.974  1   40.95  ? 409 ILE B CB  1 
ATOM   6499 C CG1 . ILE C 1 239 ? -17.984 6.863   -8.486  1   39.23  ? 409 ILE B CG1 1 
ATOM   6500 C CG2 . ILE C 1 239 ? -18.473 5.819   -10.681 1   41.36  ? 409 ILE B CG2 1 
ATOM   6501 C CD1 . ILE C 1 239 ? -19.316 6.59    -7.839  1   37.14  ? 409 ILE B CD1 1 
ATOM   6502 N N   . ARG C 1 240 ? -17.319 8.644   -12.72  1   42.94  ? 410 ARG B N   1 
ATOM   6503 C CA  . ARG C 1 240 ? -17.251 8.698   -14.169 1   45.82  ? 410 ARG B CA  1 
ATOM   6504 C C   . ARG C 1 240 ? -15.793 8.761   -14.618 1   48.17  ? 410 ARG B C   1 
ATOM   6505 O O   . ARG C 1 240 ? -15.438 8.056   -15.557 1   48.84  ? 410 ARG B O   1 
ATOM   6506 C CB  . ARG C 1 240 ? -18.05  9.843   -14.798 1   47.54  ? 410 ARG B CB  1 
ATOM   6507 C CG  . ARG C 1 240 ? -19.503 9.495   -15.081 1   47.97  ? 410 ARG B CG  1 
ATOM   6508 C CD  . ARG C 1 240 ? -20.286 10.63   -15.731 1   49.9   ? 410 ARG B CD  1 
ATOM   6509 N NE  . ARG C 1 240 ? -20.04  10.736  -17.172 1   50.51  ? 410 ARG B NE  1 
ATOM   6510 C CZ  . ARG C 1 240 ? -19.52  11.788  -17.775 1   52.61  ? 410 ARG B CZ  1 
ATOM   6511 N NH1 . ARG C 1 240 ? -19.186 11.684  -19.032 1   52.99  ? 410 ARG B NH1 1 
ATOM   6512 N NH2 . ARG C 1 240 ? -19.266 12.915  -17.13  1   53.51  ? 410 ARG B NH2 1 
ATOM   6513 N N   . GLU C 1 241 ? -14.978 9.578   -13.926 1   50.25  ? 411 GLU B N   1 
ATOM   6514 C CA  . GLU C 1 241 ? -13.563 9.771   -14.238 1   56.19  ? 411 GLU B CA  1 
ATOM   6515 C C   . GLU C 1 241 ? -12.828 8.429   -14.134 1   55.74  ? 411 GLU B C   1 
ATOM   6516 O O   . GLU C 1 241 ? -12.13  8.019   -15.058 1   57.19  ? 411 GLU B O   1 
ATOM   6517 C CB  . GLU C 1 241 ? -12.829 10.784  -13.344 1   57.21  ? 411 GLU B CB  1 
ATOM   6518 C CG  . GLU C 1 241 ? -13.353 12.221  -13.365 1   61.82  ? 411 GLU B CG  1 
ATOM   6519 C CD  . GLU C 1 241 ? -13.197 13.006  -14.664 1   72.6   ? 411 GLU B CD  1 
ATOM   6520 O OE1 . GLU C 1 241 ? -12.451 12.614  -15.592 1   73.85  ? 411 GLU B OE1 1 
ATOM   6521 O OE2 . GLU C 1 241 ? -13.865 14.06   -14.74  1   79.83  ? 411 GLU B OE2 1 
ATOM   6522 N N   . LYS C 1 242 ? -13.018 7.744   -13.003 1   52.37  ? 412 LYS B N   1 
ATOM   6523 C CA  . LYS C 1 242 ? -12.41  6.454   -12.746 1   49.54  ? 412 LYS B CA  1 
ATOM   6524 C C   . LYS C 1 242 ? -12.776 5.459   -13.847 1   51.25  ? 412 LYS B C   1 
ATOM   6525 O O   . LYS C 1 242 ? -11.902 4.735   -14.32  1   52.39  ? 412 LYS B O   1 
ATOM   6526 C CB  . LYS C 1 242 ? -12.843 5.98    -11.358 1   45.17  ? 412 LYS B CB  1 
ATOM   6527 C CG  . LYS C 1 242 ? -12.688 4.497   -11.028 1   43.78  ? 412 LYS B CG  1 
ATOM   6528 C CD  . LYS C 1 242 ? -13.227 4.209   -9.624  1   45.04  ? 412 LYS B CD  1 
ATOM   6529 C CE  . LYS C 1 242 ? -13.229 2.758   -9.197  1   42.73  ? 412 LYS B CE  1 
ATOM   6530 N NZ  . LYS C 1 242 ? -13.91  2.568   -7.909  1   41.19  ? 412 LYS B NZ  1 
ATOM   6531 N N   . TYR C 1 243 ? -14.053 5.427   -14.255 1   50.11  ? 413 TYR B N   1 
ATOM   6532 C CA  . TYR C 1 243 ? -14.487 4.409   -15.201 1   48.42  ? 413 TYR B CA  1 
ATOM   6533 C C   . TYR C 1 243 ? -14.166 4.767   -16.652 1   49.62  ? 413 TYR B C   1 
ATOM   6534 O O   . TYR C 1 243 ? -14.543 3.999   -17.538 1   50.82  ? 413 TYR B O   1 
ATOM   6535 C CB  . TYR C 1 243 ? -15.941 3.991   -14.959 1   45.06  ? 413 TYR B CB  1 
ATOM   6536 C CG  . TYR C 1 243 ? -16.055 2.981   -13.837 1   43.67  ? 413 TYR B CG  1 
ATOM   6537 C CD1 . TYR C 1 243 ? -15.977 3.398   -12.506 1   43.53  ? 413 TYR B CD1 1 
ATOM   6538 C CD2 . TYR C 1 243 ? -16.154 1.618   -14.102 1   42.41  ? 413 TYR B CD2 1 
ATOM   6539 C CE1 . TYR C 1 243 ? -16.059 2.495   -11.46  1   41.9   ? 413 TYR B CE1 1 
ATOM   6540 C CE2 . TYR C 1 243 ? -16.261 0.707   -13.063 1   41.24  ? 413 TYR B CE2 1 
ATOM   6541 C CZ  . TYR C 1 243 ? -16.196 1.146   -11.75  1   42.09  ? 413 TYR B CZ  1 
ATOM   6542 O OH  . TYR C 1 243 ? -16.251 0.272   -10.708 1   42.87  ? 413 TYR B OH  1 
ATOM   6543 N N   . LYS C 1 244 ? -13.435 5.868   -16.901 1   50.73  ? 414 LYS B N   1 
ATOM   6544 C CA  . LYS C 1 244 ? -12.836 6.117   -18.216 1   53.53  ? 414 LYS B CA  1 
ATOM   6545 C C   . LYS C 1 244 ? -11.566 5.281   -18.407 1   55.77  ? 414 LYS B C   1 
ATOM   6546 O O   . LYS C 1 244 ? -11.086 5.058   -19.531 1   60.19  ? 414 LYS B O   1 
ATOM   6547 C CB  . LYS C 1 244 ? -12.425 7.581   -18.422 1   55.72  ? 414 LYS B CB  1 
ATOM   6548 C CG  . LYS C 1 244 ? -13.564 8.582   -18.385 1   57.92  ? 414 LYS B CG  1 
ATOM   6549 C CD  . LYS C 1 244 ? -13.081 10.024  -18.392 1   62.37  ? 414 LYS B CD  1 
ATOM   6550 C CE  . LYS C 1 244 ? -14.268 10.96   -18.202 1   68.07  ? 414 LYS B CE  1 
ATOM   6551 N NZ  . LYS C 1 244 ? -13.853 12.362  -18.105 1   71.35  ? 414 LYS B NZ  1 
ATOM   6552 N N   . ASN C 1 245 ? -11.008 4.821   -17.288 1   55.3   ? 415 ASN B N   1 
ATOM   6553 C CA  . ASN C 1 245 ? -9.792  4.029   -17.279 1   57.1   ? 415 ASN B CA  1 
ATOM   6554 C C   . ASN C 1 245 ? -9.994  2.722   -18.05  1   56.81  ? 415 ASN B C   1 
ATOM   6555 O O   . ASN C 1 245 ? -11.049 2.08    -17.965 1   53.13  ? 415 ASN B O   1 
ATOM   6556 C CB  . ASN C 1 245 ? -9.341  3.769   -15.842 1   59.84  ? 415 ASN B CB  1 
ATOM   6557 C CG  . ASN C 1 245 ? -7.893  3.329   -15.762 1   68.06  ? 415 ASN B CG  1 
ATOM   6558 O OD1 . ASN C 1 245 ? -7.567  2.171   -16.061 1   71.01  ? 415 ASN B OD1 1 
ATOM   6559 N ND2 . ASN C 1 245 ? -7.009  4.247   -15.389 1   67.33  ? 415 ASN B ND2 1 
ATOM   6560 N N   . SER C 1 246 ? -8.93   2.309   -18.758 1   57.73  ? 416 SER B N   1 
ATOM   6561 C CA  . SER C 1 246 ? -8.854  1.065   -19.509 1   56.37  ? 416 SER B CA  1 
ATOM   6562 C C   . SER C 1 246 ? -9.052  -0.152  -18.606 1   54.6   ? 416 SER B C   1 
ATOM   6563 O O   . SER C 1 246 ? -9.47   -1.199  -19.065 1   56     ? 416 SER B O   1 
ATOM   6564 C CB  . SER C 1 246 ? -7.544  0.995   -20.247 1   60.29  ? 416 SER B CB  1 
ATOM   6565 O OG  . SER C 1 246 ? -7.53   1.956   -21.306 1   64.9   ? 416 SER B OG  1 
ATOM   6566 N N   . LYS C 1 247 ? -8.674  -0.036  -17.338 1   54.28  ? 417 LYS B N   1 
ATOM   6567 C CA  . LYS C 1 247 ? -8.858  -1.089  -16.358 1   58.84  ? 417 LYS B CA  1 
ATOM   6568 C C   . LYS C 1 247 ? -10.332 -1.501  -16.286 1   57.07  ? 417 LYS B C   1 
ATOM   6569 O O   . LYS C 1 247 ? -10.663 -2.64   -15.96  1   58.84  ? 417 LYS B O   1 
ATOM   6570 C CB  . LYS C 1 247 ? -8.398  -0.445  -15.04  1   63.11  ? 417 LYS B CB  1 
ATOM   6571 C CG  . LYS C 1 247 ? -8.543  -1.196  -13.73  1   63.74  ? 417 LYS B CG  1 
ATOM   6572 C CD  . LYS C 1 247 ? -8.036  -0.281  -12.608 1   72.31  ? 417 LYS B CD  1 
ATOM   6573 C CE  . LYS C 1 247 ? -7.397  -0.959  -11.416 1   71.68  ? 417 LYS B CE  1 
ATOM   6574 N NZ  . LYS C 1 247 ? -8.248  -2.085  -11.031 1   62.72  ? 417 LYS B NZ  1 
ATOM   6575 N N   . TYR C 1 248 ? -11.233 -0.564  -16.588 1   55.11  ? 418 TYR B N   1 
ATOM   6576 C CA  . TYR C 1 248 ? -12.668 -0.825  -16.534 1   52.52  ? 418 TYR B CA  1 
ATOM   6577 C C   . TYR C 1 248 ? -13.268 -0.687  -17.925 1   52.16  ? 418 TYR B C   1 
ATOM   6578 O O   . TYR C 1 248 ? -14.468 -0.452  -18.059 1   50.68  ? 418 TYR B O   1 
ATOM   6579 C CB  . TYR C 1 248 ? -13.364 0.123   -15.554 1   49.82  ? 418 TYR B CB  1 
ATOM   6580 C CG  . TYR C 1 248 ? -12.709 0.18    -14.182 1   51.65  ? 418 TYR B CG  1 
ATOM   6581 C CD1 . TYR C 1 248 ? -12.791 -0.896  -13.299 1   49.54  ? 418 TYR B CD1 1 
ATOM   6582 C CD2 . TYR C 1 248 ? -12.001 1.307   -13.783 1   50.26  ? 418 TYR B CD2 1 
ATOM   6583 C CE1 . TYR C 1 248 ? -12.208 -0.852  -12.04  1   47.25  ? 418 TYR B CE1 1 
ATOM   6584 C CE2 . TYR C 1 248 ? -11.425 1.357   -12.526 1   51.53  ? 418 TYR B CE2 1 
ATOM   6585 C CZ  . TYR C 1 248 ? -11.524 0.282   -11.654 1   50.83  ? 418 TYR B CZ  1 
ATOM   6586 O OH  . TYR C 1 248 ? -10.899 0.364   -10.429 1   64.33  ? 418 TYR B OH  1 
ATOM   6587 N N   . HIS C 1 249 ? -12.409 -0.809  -18.935 1   50.9   ? 419 HIS B N   1 
ATOM   6588 C CA  . HIS C 1 249 ? -12.832 -0.901  -20.322 1   54.39  ? 419 HIS B CA  1 
ATOM   6589 C C   . HIS C 1 249 ? -13.478 0.402   -20.788 1   53.17  ? 419 HIS B C   1 
ATOM   6590 O O   . HIS C 1 249 ? -14.166 0.41    -21.785 1   54.17  ? 419 HIS B O   1 
ATOM   6591 C CB  . HIS C 1 249 ? -13.661 -2.169  -20.569 1   56.8   ? 419 HIS B CB  1 
ATOM   6592 C CG  . HIS C 1 249 ? -13.008 -3.43   -20.091 1   62.98  ? 419 HIS B CG  1 
ATOM   6593 N ND1 . HIS C 1 249 ? -13.203 -3.961  -18.822 1   67.68  ? 419 HIS B ND1 1 
ATOM   6594 C CD2 . HIS C 1 249 ? -12.135 -4.247  -20.706 1   64.44  ? 419 HIS B CD2 1 
ATOM   6595 C CE1 . HIS C 1 249 ? -12.462 -5.067  -18.677 1   66.08  ? 419 HIS B CE1 1 
ATOM   6596 N NE2 . HIS C 1 249 ? -11.804 -5.253  -19.814 1   67.61  ? 419 HIS B NE2 1 
ATOM   6597 N N   . GLY C 1 250 ? -13.22  1.512   -20.096 1   53.75  ? 420 GLY B N   1 
ATOM   6598 C CA  . GLY C 1 250 ? -13.704 2.817   -20.525 1   54.9   ? 420 GLY B CA  1 
ATOM   6599 C C   . GLY C 1 250 ? -15.237 2.9     -20.556 1   55.09  ? 420 GLY B C   1 
ATOM   6600 O O   . GLY C 1 250 ? -15.807 3.71    -21.29  1   56.32  ? 420 GLY B O   1 
ATOM   6601 N N   . VAL C 1 251 ? -15.907 2.113   -19.709 1   49.34  ? 421 VAL B N   1 
ATOM   6602 C CA  . VAL C 1 251 ? -17.345 1.98    -19.793 1   47.23  ? 421 VAL B CA  1 
ATOM   6603 C C   . VAL C 1 251 ? -18.057 3.313   -19.551 1   49.48  ? 421 VAL B C   1 
ATOM   6604 O O   . VAL C 1 251 ? -19.082 3.574   -20.168 1   51.28  ? 421 VAL B O   1 
ATOM   6605 C CB  . VAL C 1 251 ? -17.861 0.849   -18.898 1   43.85  ? 421 VAL B CB  1 
ATOM   6606 C CG1 . VAL C 1 251 ? -17.463 -0.491  -19.502 1   42.78  ? 421 VAL B CG1 1 
ATOM   6607 C CG2 . VAL C 1 251 ? -17.418 0.976   -17.441 1   41.43  ? 421 VAL B CG2 1 
ATOM   6608 N N   . SER C 1 252 ? -17.485 4.214   -18.746 1   49.74  ? 422 SER B N   1 
ATOM   6609 C CA  . SER C 1 252 ? -18.211 5.44    -18.438 1   49.49  ? 422 SER B CA  1 
ATOM   6610 C C   . SER C 1 252 ? -18.434 6.267   -19.696 1   50.51  ? 422 SER B C   1 
ATOM   6611 O O   . SER C 1 252 ? -19.177 7.23    -19.656 1   51.2   ? 422 SER B O   1 
ATOM   6612 C CB  . SER C 1 252 ? -17.606 6.261   -17.302 1   47.57  ? 422 SER B CB  1 
ATOM   6613 O OG  . SER C 1 252 ? -16.355 6.817   -17.651 1   49.02  ? 422 SER B OG  1 
ATOM   6614 N N   . LEU C 1 253 ? -17.772 5.908   -20.797 1   54.12  ? 423 LEU B N   1 
ATOM   6615 C CA  . LEU C 1 253 ? -17.894 6.629   -22.059 1   55.01  ? 423 LEU B CA  1 
ATOM   6616 C C   . LEU C 1 253 ? -18.964 5.995   -22.948 1   56.12  ? 423 LEU B C   1 
ATOM   6617 O O   . LEU C 1 253 ? -19.311 6.586   -23.96  1   58.4   ? 423 LEU B O   1 
ATOM   6618 C CB  . LEU C 1 253 ? -16.549 6.637   -22.787 1   57.84  ? 423 LEU B CB  1 
ATOM   6619 C CG  . LEU C 1 253 ? -15.368 7.365   -22.121 1   59.97  ? 423 LEU B CG  1 
ATOM   6620 C CD1 . LEU C 1 253 ? -14.156 6.928   -22.931 1   60.58  ? 423 LEU B CD1 1 
ATOM   6621 C CD2 . LEU C 1 253 ? -15.463 8.915   -22.101 1   61.03  ? 423 LEU B CD2 1 
ATOM   6622 N N   . LEU C 1 254 ? -19.487 4.807   -22.591 1   55.14  ? 424 LEU B N   1 
ATOM   6623 C CA  . LEU C 1 254 ? -20.614 4.208   -23.304 1   55.18  ? 424 LEU B CA  1 
ATOM   6624 C C   . LEU C 1 254 ? -21.815 5.149   -23.23  1   56.99  ? 424 LEU B C   1 
ATOM   6625 O O   . LEU C 1 254 ? -21.901 5.947   -22.303 1   57.65  ? 424 LEU B O   1 
ATOM   6626 C CB  . LEU C 1 254 ? -20.949 2.827   -22.744 1   50.67  ? 424 LEU B CB  1 
ATOM   6627 C CG  . LEU C 1 254 ? -19.953 1.717   -23.098 1   49.95  ? 424 LEU B CG  1 
ATOM   6628 C CD1 . LEU C 1 254 ? -20.277 0.381   -22.458 1   46     ? 424 LEU B CD1 1 
ATOM   6629 C CD2 . LEU C 1 254 ? -19.795 1.582   -24.626 1   51.54  ? 424 LEU B CD2 1 
ATOM   6630 N N   . ASN C 1 255 ? -22.695 5.105   -24.244 1   58.9   ? 425 ASN B N   1 
ATOM   6631 C CA  . ASN C 1 255 ? -23.906 5.92    -24.249 1   60.41  ? 425 ASN B CA  1 
ATOM   6632 C C   . ASN C 1 255 ? -25.061 5.152   -23.61  1   57.66  ? 425 ASN B C   1 
ATOM   6633 O O   . ASN C 1 255 ? -25.348 4.014   -23.99  1   56.8   ? 425 ASN B O   1 
ATOM   6634 C CB  . ASN C 1 255 ? -24.339 6.319   -25.652 1   64.21  ? 425 ASN B CB  1 
ATOM   6635 C CG  . ASN C 1 255 ? -23.539 7.476   -26.208 1   68.02  ? 425 ASN B CG  1 
ATOM   6636 O OD1 . ASN C 1 255 ? -23.281 7.49    -27.417 1   71.4   ? 425 ASN B OD1 1 
ATOM   6637 N ND2 . ASN C 1 255 ? -23.198 8.467   -25.383 1   65.53  ? 425 ASN B ND2 1 
ATOM   6638 N N   . PRO C 1 256 ? -25.756 5.741   -22.613 1   55.42  ? 426 PRO B N   1 
ATOM   6639 C CA  . PRO C 1 256 ? -26.911 5.069   -22.024 1   53.51  ? 426 PRO B CA  1 
ATOM   6640 C C   . PRO C 1 256 ? -28.048 4.922   -23.039 1   56.91  ? 426 PRO B C   1 
ATOM   6641 O O   . PRO C 1 256 ? -28.151 5.718   -23.978 1   57.79  ? 426 PRO B O   1 
ATOM   6642 C CB  . PRO C 1 256 ? -27.267 5.97    -20.851 1   52.3   ? 426 PRO B CB  1 
ATOM   6643 C CG  . PRO C 1 256 ? -26.734 7.318   -21.229 1   54.08  ? 426 PRO B CG  1 
ATOM   6644 C CD  . PRO C 1 256 ? -25.464 7.055   -22.018 1   54.29  ? 426 PRO B CD  1 
ATOM   6645 N N   . PRO C 1 257 ? -28.954 3.913   -22.888 1   57.1   ? 427 PRO B N   1 
ATOM   6646 C CA  . PRO C 1 257 ? -30.091 3.753   -23.808 1   56.7   ? 427 PRO B CA  1 
ATOM   6647 C C   . PRO C 1 257 ? -31.128 4.828   -23.508 1   58.83  ? 427 PRO B C   1 
ATOM   6648 O O   . PRO C 1 257 ? -31.342 5.184   -22.358 1   55     ? 427 PRO B O   1 
ATOM   6649 C CB  . PRO C 1 257 ? -30.632 2.359   -23.496 1   55.03  ? 427 PRO B CB  1 
ATOM   6650 C CG  . PRO C 1 257 ? -30.219 2.119   -22.033 1   53.69  ? 427 PRO B CG  1 
ATOM   6651 C CD  . PRO C 1 257 ? -28.955 2.919   -21.794 1   53.06  ? 427 PRO B CD  1 
ATOM   6652 N N   . GLU C 1 258 ? -31.765 5.351   -24.561 1   68.06  ? 428 GLU B N   1 
ATOM   6653 C CA  . GLU C 1 258 ? -32.782 6.378   -24.4   1   71.77  ? 428 GLU B CA  1 
ATOM   6654 C C   . GLU C 1 258 ? -33.974 5.84    -23.602 1   69.19  ? 428 GLU B C   1 
ATOM   6655 O O   . GLU C 1 258 ? -34.596 6.61    -22.88  1   67.59  ? 428 GLU B O   1 
ATOM   6656 C CB  . GLU C 1 258 ? -33.222 6.912   -25.758 1   80.98  ? 428 GLU B CB  1 
ATOM   6657 C CG  . GLU C 1 258 ? -32.089 7.454   -26.628 1   89.15  ? 428 GLU B CG  1 
ATOM   6658 C CD  . GLU C 1 258 ? -32.509 7.774   -28.072 1   101.77 ? 428 GLU B CD  1 
ATOM   6659 O OE1 . GLU C 1 258 ? -33.72  7.65    -28.411 1   95.66  ? 428 GLU B OE1 1 
ATOM   6660 O OE2 . GLU C 1 258 ? -31.618 8.144   -28.886 1   102.67 ? 428 GLU B OE2 1 
ATOM   6661 N N   . THR C 1 259 ? -34.286 4.533   -23.752 1   67.33  ? 429 THR B N   1 
ATOM   6662 C CA  . THR C 1 259 ? -35.441 3.864   -23.146 1   68.62  ? 429 THR B CA  1 
ATOM   6663 C C   . THR C 1 259 ? -35.143 2.389   -22.852 1   68.13  ? 429 THR B C   1 
ATOM   6664 O O   . THR C 1 259 ? -34.362 1.765   -23.563 1   67.81  ? 429 THR B O   1 
ATOM   6665 C CB  . THR C 1 259 ? -36.706 3.937   -24.021 1   71.21  ? 429 THR B CB  1 
ATOM   6666 O OG1 . THR C 1 259 ? -36.503 3.165   -25.207 1   67.95  ? 429 THR B OG1 1 
ATOM   6667 C CG2 . THR C 1 259 ? -37.227 5.343   -24.264 1   70.43  ? 429 THR B CG2 1 
ATOM   6668 N N   . LEU C 1 260 ? -35.877 1.801   -21.89  1   69.06  ? 430 LEU B N   1 
ATOM   6669 C CA  . LEU C 1 260 ? -35.638 0.441   -21.428 1   71     ? 430 LEU B CA  1 
ATOM   6670 C C   . LEU C 1 260 ? -36.56  -0.592  -22.076 1   80.36  ? 430 LEU B C   1 
ATOM   6671 O O   . LEU C 1 260 ? -36.321 -1.796  -21.929 1   79.02  ? 430 LEU B O   1 
ATOM   6672 C CB  . LEU C 1 260 ? -35.814 0.418   -19.914 1   67.93  ? 430 LEU B CB  1 
ATOM   6673 C CG  . LEU C 1 260 ? -34.824 1.264   -19.115 1   68.9   ? 430 LEU B CG  1 
ATOM   6674 C CD1 . LEU C 1 260 ? -34.97  0.999   -17.627 1   69.84  ? 430 LEU B CD1 1 
ATOM   6675 C CD2 . LEU C 1 260 ? -33.404 1.006   -19.58  1   63.11  ? 430 LEU B CD2 1 
ATOM   6676 N N   . ASN C 1 261 ? -37.643 -0.128  -22.722 1   92.79  ? 431 ASN B N   1 
ATOM   6677 C CA  . ASN C 1 261 ? -38.689 -0.995  -23.264 1   100.63 ? 431 ASN B CA  1 
ATOM   6678 C C   . ASN C 1 261 ? -39.036 -2.114  -22.274 1   98.09  ? 431 ASN B C   1 
ATOM   6679 O O   . ASN C 1 261 ? -38.961 -3.293  -22.624 1   95.99  ? 431 ASN B O   1 
ATOM   6680 C CB  . ASN C 1 261 ? -38.321 -1.57   -24.633 1   107    ? 431 ASN B CB  1 
ATOM   6681 C CG  . ASN C 1 261 ? -37.978 -0.517  -25.666 1   110.42 ? 431 ASN B CG  1 
ATOM   6682 O OD1 . ASN C 1 261 ? -36.851 -0.502  -26.179 1   118.25 ? 431 ASN B OD1 1 
ATOM   6683 N ND2 . ASN C 1 261 ? -38.919 0.358   -26     1   101.42 ? 431 ASN B ND2 1 
ATOM   6684 N N   . VAL C 1 262 ? -39.431 -1.72   -21.051 1   92.89  ? 432 VAL B N   1 
ATOM   6685 C CA  . VAL C 1 262 ? -39.579 -2.624  -19.92  1   96.07  ? 432 VAL B CA  1 
ATOM   6686 C C   . VAL C 1 262 ? -41.069 -2.699  -19.539 1   103.85 ? 432 VAL B C   1 
ATOM   6687 O O   . VAL C 1 262 ? -41.912 -2.602  -20.462 1   104.26 ? 432 VAL B O   1 
ATOM   6688 C CB  . VAL C 1 262 ? -38.694 -2.166  -18.734 1   92.39  ? 432 VAL B CB  1 
ATOM   6689 C CG1 . VAL C 1 262 ? -39.364 -1.115  -17.848 1   90.8   ? 432 VAL B CG1 1 
ATOM   6690 C CG2 . VAL C 1 262 ? -38.178 -3.32   -17.882 1   83.58  ? 432 VAL B CG2 1 
ATOM   6691 N N   . SER D 2 4   ? -15.015 4.634   28.521  1   69.3   ? 0   SER C N   1 
ATOM   6692 C CA  . SER D 2 4   ? -16.509 4.497   28.532  1   73.74  ? 0   SER C CA  1 
ATOM   6693 C C   . SER D 2 4   ? -17.176 5.838   28.219  1   67.41  ? 0   SER C C   1 
ATOM   6694 O O   . SER D 2 4   ? -17.915 6.001   27.247  1   65.27  ? 0   SER C O   1 
ATOM   6695 C CB  . SER D 2 4   ? -17.02  3.961   29.87   1   73.13  ? 0   SER C CB  1 
ATOM   6696 O OG  . SER D 2 4   ? -16.55  2.643   30.105  1   77.52  ? 0   SER C OG  1 
ATOM   6697 N N   . MET D 2 5   ? -16.889 6.793   29.103  1   65.63  ? 1   MET C N   1 
ATOM   6698 C CA  . MET D 2 5   ? -17.314 8.172   28.997  1   61.77  ? 1   MET C CA  1 
ATOM   6699 C C   . MET D 2 5   ? -16.128 9       28.508  1   61.63  ? 1   MET C C   1 
ATOM   6700 O O   . MET D 2 5   ? -16.167 10.229  28.542  1   61.85  ? 1   MET C O   1 
ATOM   6701 C CB  . MET D 2 5   ? -17.757 8.657   30.382  1   61.22  ? 1   MET C CB  1 
ATOM   6702 C CG  . MET D 2 5   ? -18.85  7.817   30.993  1   60.33  ? 1   MET C CG  1 
ATOM   6703 S SD  . MET D 2 5   ? -20.332 7.832   29.963  1   60.33  ? 1   MET C SD  1 
ATOM   6704 C CE  . MET D 2 5   ? -20.803 9.563   30.101  1   59.13  ? 1   MET C CE  1 
ATOM   6705 N N   . GLU D 2 6   ? -15.079 8.318   28.042  1   61.01  ? 2   GLU C N   1 
ATOM   6706 C CA  . GLU D 2 6   ? -13.914 8.984   27.49   1   64.54  ? 2   GLU C CA  1 
ATOM   6707 C C   . GLU D 2 6   ? -14.325 9.959   26.381  1   60.56  ? 2   GLU C C   1 
ATOM   6708 O O   . GLU D 2 6   ? -13.714 11.014  26.256  1   60.46  ? 2   GLU C O   1 
ATOM   6709 C CB  . GLU D 2 6   ? -12.884 7.963   26.997  1   71.5   ? 2   GLU C CB  1 
ATOM   6710 C CG  . GLU D 2 6   ? -11.589 8.577   26.464  1   86.31  ? 2   GLU C CG  1 
ATOM   6711 C CD  . GLU D 2 6   ? -10.645 9.349   27.38   1   98.41  ? 2   GLU C CD  1 
ATOM   6712 O OE1 . GLU D 2 6   ? -10.833 9.253   28.621  1   103.43 ? 2   GLU C OE1 1 
ATOM   6713 O OE2 . GLU D 2 6   ? -9.76   10.085  26.861  1   97.57  ? 2   GLU C OE2 1 
ATOM   6714 N N   . ASN D 2 7   ? -15.344 9.606   25.579  1   57.62  ? 3   ASN C N   1 
ATOM   6715 C CA  . ASN D 2 7   ? -15.693 10.432  24.426  1   58.06  ? 3   ASN C CA  1 
ATOM   6716 C C   . ASN D 2 7   ? -16.618 11.579  24.792  1   55.81  ? 3   ASN C C   1 
ATOM   6717 O O   . ASN D 2 7   ? -16.85  12.45   23.96   1   56.77  ? 3   ASN C O   1 
ATOM   6718 C CB  . ASN D 2 7   ? -16.298 9.667   23.256  1   58.5   ? 3   ASN C CB  1 
ATOM   6719 C CG  . ASN D 2 7   ? -15.292 8.693   22.703  1   62.22  ? 3   ASN C CG  1 
ATOM   6720 O OD1 . ASN D 2 7   ? -14.098 9.045   22.56   1   64.8   ? 3   ASN C OD1 1 
ATOM   6721 N ND2 . ASN D 2 7   ? -15.743 7.456   22.501  1   58.3   ? 3   ASN C ND2 1 
ATOM   6722 N N   . PHE D 2 8   ? -17.133 11.577  26.021  1   54.05  ? 4   PHE C N   1 
ATOM   6723 C CA  . PHE D 2 8   ? -17.978 12.668  26.46   1   53.23  ? 4   PHE C CA  1 
ATOM   6724 C C   . PHE D 2 8   ? -17.171 13.695  27.25   1   55.81  ? 4   PHE C C   1 
ATOM   6725 O O   . PHE D 2 8   ? -16.436 13.341  28.181  1   56.93  ? 4   PHE C O   1 
ATOM   6726 C CB  . PHE D 2 8   ? -19.158 12.061  27.205  1   50.13  ? 4   PHE C CB  1 
ATOM   6727 C CG  . PHE D 2 8   ? -20.049 11.272  26.269  1   48.45  ? 4   PHE C CG  1 
ATOM   6728 C CD1 . PHE D 2 8   ? -20.854 11.923  25.351  1   46.89  ? 4   PHE C CD1 1 
ATOM   6729 C CD2 . PHE D 2 8   ? -20.096 9.88    26.331  1   48.7   ? 4   PHE C CD2 1 
ATOM   6730 C CE1 . PHE D 2 8   ? -21.685 11.202  24.5    1   46.26  ? 4   PHE C CE1 1 
ATOM   6731 C CE2 . PHE D 2 8   ? -20.928 9.157   25.479  1   47.38  ? 4   PHE C CE2 1 
ATOM   6732 C CZ  . PHE D 2 8   ? -21.71  9.822   24.55   1   46.55  ? 4   PHE C CZ  1 
ATOM   6733 N N   . GLN D 2 9   ? -17.339 14.967  26.85   1   56.76  ? 5   GLN C N   1 
ATOM   6734 C CA  . GLN D 2 9   ? -16.871 16.134  27.586  1   60.49  ? 5   GLN C CA  1 
ATOM   6735 C C   . GLN D 2 9   ? -18.06  16.811  28.28   1   60.7   ? 5   GLN C C   1 
ATOM   6736 O O   . GLN D 2 9   ? -18.988 17.285  27.62   1   59.62  ? 5   GLN C O   1 
ATOM   6737 C CB  . GLN D 2 9   ? -16.231 17.066  26.557  1   63.87  ? 5   GLN C CB  1 
ATOM   6738 C CG  . GLN D 2 9   ? -15.763 18.405  27.112  1   72.27  ? 5   GLN C CG  1 
ATOM   6739 C CD  . GLN D 2 9   ? -14.425 18.3    27.808  1   80.73  ? 5   GLN C CD  1 
ATOM   6740 O OE1 . GLN D 2 9   ? -13.371 18.372  27.166  1   90.07  ? 5   GLN C OE1 1 
ATOM   6741 N NE2 . GLN D 2 9   ? -14.448 18.124  29.124  1   79.65  ? 5   GLN C NE2 1 
ATOM   6742 N N   . LYS D 2 10  ? -18.049 16.868  29.619  1   62.26  ? 6   LYS C N   1 
ATOM   6743 C CA  . LYS D 2 10  ? -19.08  17.621  30.33   1   63.04  ? 6   LYS C CA  1 
ATOM   6744 C C   . LYS D 2 10  ? -18.996 19.095  29.953  1   61.87  ? 6   LYS C C   1 
ATOM   6745 O O   . LYS D 2 10  ? -17.903 19.632  29.759  1   63.62  ? 6   LYS C O   1 
ATOM   6746 C CB  . LYS D 2 10  ? -18.862 17.684  31.845  1   69.06  ? 6   LYS C CB  1 
ATOM   6747 C CG  . LYS D 2 10  ? -19.5   16.606  32.696  1   71.8   ? 6   LYS C CG  1 
ATOM   6748 C CD  . LYS D 2 10  ? -19.392 16.969  34.177  1   77.33  ? 6   LYS C CD  1 
ATOM   6749 C CE  . LYS D 2 10  ? -18.004 16.984  34.75   1   78.68  ? 6   LYS C CE  1 
ATOM   6750 N NZ  . LYS D 2 10  ? -18.057 17.492  36.124  1   78.05  ? 6   LYS C NZ  1 
ATOM   6751 N N   . VAL D 2 11  ? -20.159 19.736  29.884  1   58.15  ? 7   VAL C N   1 
ATOM   6752 C CA  . VAL D 2 11  ? -20.248 21.158  29.605  1   59.08  ? 7   VAL C CA  1 
ATOM   6753 C C   . VAL D 2 11  ? -20.796 21.881  30.838  1   61.13  ? 7   VAL C C   1 
ATOM   6754 O O   . VAL D 2 11  ? -20.151 22.771  31.362  1   62.34  ? 7   VAL C O   1 
ATOM   6755 C CB  . VAL D 2 11  ? -21.099 21.403  28.351  1   57.35  ? 7   VAL C CB  1 
ATOM   6756 C CG1 . VAL D 2 11  ? -21.458 22.87   28.157  1   56.6   ? 7   VAL C CG1 1 
ATOM   6757 C CG2 . VAL D 2 11  ? -20.388 20.863  27.118  1   57.99  ? 7   VAL C CG2 1 
ATOM   6758 N N   . GLU D 2 12  ? -21.985 21.497  31.32   1   62.04  ? 8   GLU C N   1 
ATOM   6759 C CA  . GLU D 2 12  ? -22.508 22.077  32.544  1   65.68  ? 8   GLU C CA  1 
ATOM   6760 C C   . GLU D 2 12  ? -23.541 21.152  33.184  1   66.93  ? 8   GLU C C   1 
ATOM   6761 O O   . GLU D 2 12  ? -24.068 20.248  32.527  1   64.49  ? 8   GLU C O   1 
ATOM   6762 C CB  . GLU D 2 12  ? -23.099 23.455  32.25   1   69.61  ? 8   GLU C CB  1 
ATOM   6763 C CG  . GLU D 2 12  ? -24.326 23.394  31.35   1   74.49  ? 8   GLU C CG  1 
ATOM   6764 C CD  . GLU D 2 12  ? -24.739 24.681  30.666  1   82.18  ? 8   GLU C CD  1 
ATOM   6765 O OE1 . GLU D 2 12  ? -23.882 25.244  29.952  1   82.56  ? 8   GLU C OE1 1 
ATOM   6766 O OE2 . GLU D 2 12  ? -25.915 25.096  30.803  1   86.4   ? 8   GLU C OE2 1 
ATOM   6767 N N   . LYS D 2 13  ? -23.814 21.403  34.475  1   71.03  ? 9   LYS C N   1 
ATOM   6768 C CA  . LYS D 2 13  ? -24.971 20.852  35.169  1   76.44  ? 9   LYS C CA  1 
ATOM   6769 C C   . LYS D 2 13  ? -26.254 21.426  34.558  1   71.61  ? 9   LYS C C   1 
ATOM   6770 O O   . LYS D 2 13  ? -26.294 22.585  34.162  1   77.04  ? 9   LYS C O   1 
ATOM   6771 C CB  . LYS D 2 13  ? -24.906 21.281  36.641  1   85     ? 9   LYS C CB  1 
ATOM   6772 C CG  . LYS D 2 13  ? -23.745 20.67   37.432  1   91.55  ? 9   LYS C CG  1 
ATOM   6773 C CD  . LYS D 2 13  ? -23.635 21.092  38.892  1   94.05  ? 9   LYS C CD  1 
ATOM   6774 C CE  . LYS D 2 13  ? -22.48  20.418  39.579  1   105.8  ? 9   LYS C CE  1 
ATOM   6775 N NZ  . LYS D 2 13  ? -22.327 20.817  40.983  1   109.99 ? 9   LYS C NZ  1 
ATOM   6776 N N   . ILE D 2 14  ? -27.319 20.632  34.49   1   65.6   ? 10  ILE C N   1 
ATOM   6777 C CA  . ILE D 2 14  ? -28.594 21.174  34.047  1   68.86  ? 10  ILE C CA  1 
ATOM   6778 C C   . ILE D 2 14  ? -29.75  20.703  34.93   1   73.78  ? 10  ILE C C   1 
ATOM   6779 O O   . ILE D 2 14  ? -30.904 20.9    34.559  1   78.42  ? 10  ILE C O   1 
ATOM   6780 C CB  . ILE D 2 14  ? -28.866 20.941  32.548  1   68.61  ? 10  ILE C CB  1 
ATOM   6781 C CG1 . ILE D 2 14  ? -28.845 19.498  32.146  1   62.45  ? 10  ILE C CG1 1 
ATOM   6782 C CG2 . ILE D 2 14  ? -27.9   21.746  31.692  1   77.15  ? 10  ILE C CG2 1 
ATOM   6783 C CD1 . ILE D 2 14  ? -29.048 19.285  30.657  1   57.84  ? 10  ILE C CD1 1 
ATOM   6784 N N   . GLY D 2 15  ? -29.446 20.117  36.101  1   74.08  ? 11  GLY C N   1 
ATOM   6785 C CA  . GLY D 2 15  ? -30.467 19.903  37.112  1   75.36  ? 11  GLY C CA  1 
ATOM   6786 C C   . GLY D 2 15  ? -30.607 18.437  37.485  1   80.6   ? 11  GLY C C   1 
ATOM   6787 O O   . GLY D 2 15  ? -29.754 17.64   37.135  1   85.44  ? 11  GLY C O   1 
ATOM   6788 N N   . GLU D 2 16  ? -31.694 18.101  38.192  1   88.32  ? 12  GLU C N   1 
ATOM   6789 C CA  . GLU D 2 16  ? -31.838 16.807  38.843  1   93.78  ? 12  GLU C CA  1 
ATOM   6790 C C   . GLU D 2 16  ? -33.305 16.406  38.771  1   105.56 ? 12  GLU C C   1 
ATOM   6791 O O   . GLU D 2 16  ? -34.162 17.151  39.247  1   107.5  ? 12  GLU C O   1 
ATOM   6792 C CB  . GLU D 2 16  ? -31.376 16.837  40.304  1   90.08  ? 12  GLU C CB  1 
ATOM   6793 C CG  . GLU D 2 16  ? -30.179 17.75   40.557  1   96.15  ? 12  GLU C CG  1 
ATOM   6794 C CD  . GLU D 2 16  ? -29.29  17.374  41.726  1   103.83 ? 12  GLU C CD  1 
ATOM   6795 O OE1 . GLU D 2 16  ? -29.627 16.351  42.364  1   96.01  ? 12  GLU C OE1 1 
ATOM   6796 O OE2 . GLU D 2 16  ? -28.277 18.082  41.981  1   104.43 ? 12  GLU C OE2 1 
ATOM   6797 N N   . GLY D 2 17  ? -33.576 15.241  38.155  1   124.92 ? 13  GLY C N   1 
ATOM   6798 C CA  . GLY D 2 17  ? -34.937 14.743  37.989  1   136.51 ? 13  GLY C CA  1 
ATOM   6799 C C   . GLY D 2 17  ? -35.442 14.053  39.258  1   148.7  ? 13  GLY C C   1 
ATOM   6800 O O   . GLY D 2 17  ? -34.988 14.363  40.362  1   154.55 ? 13  GLY C O   1 
ATOM   6801 N N   . THR D 2 18  ? -36.373 13.1    39.08   1   148.11 ? 14  THR C N   1 
ATOM   6802 C CA  . THR D 2 18  ? -36.879 12.27   40.173  1   139.51 ? 14  THR C CA  1 
ATOM   6803 C C   . THR D 2 18  ? -35.76  11.38   40.753  1   119.15 ? 14  THR C C   1 
ATOM   6804 O O   . THR D 2 18  ? -35.838 10.939  41.898  1   100.95 ? 14  THR C O   1 
ATOM   6805 C CB  . THR D 2 18  ? -38.195 11.552  39.809  1   135.04 ? 14  THR C CB  1 
ATOM   6806 O OG1 . THR D 2 18  ? -38.184 11.102  38.453  1   123.76 ? 14  THR C OG1 1 
ATOM   6807 C CG2 . THR D 2 18  ? -39.433 12.419  40.001  1   122.46 ? 14  THR C CG2 1 
ATOM   6808 N N   . TYR D 2 19  ? -34.688 11.234  39.962  1   116.61 ? 15  TYR C N   1 
ATOM   6809 C CA  . TYR D 2 19  ? -33.503 10.44   40.386  1   113.19 ? 15  TYR C CA  1 
ATOM   6810 C C   . TYR D 2 19  ? -32.294 10.839  39.538  1   105.33 ? 15  TYR C C   1 
ATOM   6811 O O   . TYR D 2 19  ? -32.504 11.406  38.452  1   104.59 ? 15  TYR C O   1 
ATOM   6812 C CB  . TYR D 2 19  ? -33.784 8.942   40.277  1   112.07 ? 15  TYR C CB  1 
ATOM   6813 C CG  . TYR D 2 19  ? -33.839 8.386   38.863  1   105.53 ? 15  TYR C CG  1 
ATOM   6814 C CD1 . TYR D 2 19  ? -34.645 8.961   37.887  1   107.97 ? 15  TYR C CD1 1 
ATOM   6815 C CD2 . TYR D 2 19  ? -33.102 7.265   38.52   1   88.1   ? 15  TYR C CD2 1 
ATOM   6816 C CE1 . TYR D 2 19  ? -34.716 8.434   36.61   1   92.37  ? 15  TYR C CE1 1 
ATOM   6817 C CE2 . TYR D 2 19  ? -33.158 6.739   37.244  1   80.84  ? 15  TYR C CE2 1 
ATOM   6818 C CZ  . TYR D 2 19  ? -33.963 7.322   36.288  1   82.79  ? 15  TYR C CZ  1 
ATOM   6819 O OH  . TYR D 2 19  ? -33.998 6.788   35.038  1   85.32  ? 15  TYR C OH  1 
ATOM   6820 N N   . GLY D 2 20  ? -31.077 10.549  40.002  1   90.52  ? 16  GLY C N   1 
ATOM   6821 C CA  . GLY D 2 20  ? -29.845 10.926  39.332  1   92.95  ? 16  GLY C CA  1 
ATOM   6822 C C   . GLY D 2 20  ? -29.702 12.442  39.141  1   96.71  ? 16  GLY C C   1 
ATOM   6823 O O   . GLY D 2 20  ? -30.468 13.232  39.69   1   99.75  ? 16  GLY C O   1 
ATOM   6824 N N   . VAL D 2 21  ? -28.697 12.842  38.35   1   94.85  ? 17  VAL C N   1 
ATOM   6825 C CA  . VAL D 2 21  ? -28.316 14.236  38.154  1   83.29  ? 17  VAL C CA  1 
ATOM   6826 C C   . VAL D 2 21  ? -27.855 14.401  36.704  1   73.81  ? 17  VAL C C   1 
ATOM   6827 O O   . VAL D 2 21  ? -27.28  13.478  36.138  1   73.09  ? 17  VAL C O   1 
ATOM   6828 C CB  . VAL D 2 21  ? -27.278 14.699  39.19   1   74.31  ? 17  VAL C CB  1 
ATOM   6829 C CG1 . VAL D 2 21  ? -26.798 16.118  38.899  1   82.23  ? 17  VAL C CG1 1 
ATOM   6830 C CG2 . VAL D 2 21  ? -27.805 14.567  40.609  1   71.5   ? 17  VAL C CG2 1 
ATOM   6831 N N   . VAL D 2 22  ? -28.187 15.544  36.087  1   66.62  ? 18  VAL C N   1 
ATOM   6832 C CA  . VAL D 2 22  ? -28.295 15.65   34.635  1   60.44  ? 18  VAL C CA  1 
ATOM   6833 C C   . VAL D 2 22  ? -27.289 16.683  34.137  1   58.73  ? 18  VAL C C   1 
ATOM   6834 O O   . VAL D 2 22  ? -27.246 17.796  34.644  1   58.34  ? 18  VAL C O   1 
ATOM   6835 C CB  . VAL D 2 22  ? -29.722 15.988  34.154  1   56.06  ? 18  VAL C CB  1 
ATOM   6836 C CG1 . VAL D 2 22  ? -29.852 15.939  32.644  1   53.53  ? 18  VAL C CG1 1 
ATOM   6837 C CG2 . VAL D 2 22  ? -30.774 15.069  34.757  1   56.41  ? 18  VAL C CG2 1 
ATOM   6838 N N   . TYR D 2 23  ? -26.475 16.301  33.146  1   56.38  ? 19  TYR C N   1 
ATOM   6839 C CA  . TYR D 2 23  ? -25.464 17.193  32.604  1   53.56  ? 19  TYR C CA  1 
ATOM   6840 C C   . TYR D 2 23  ? -25.647 17.286  31.102  1   50.95  ? 19  TYR C C   1 
ATOM   6841 O O   . TYR D 2 23  ? -26.108 16.348  30.44   1   49.38  ? 19  TYR C O   1 
ATOM   6842 C CB  . TYR D 2 23  ? -24.042 16.724  32.862  1   56.71  ? 19  TYR C CB  1 
ATOM   6843 C CG  . TYR D 2 23  ? -23.756 16.368  34.314  1   63.18  ? 19  TYR C CG  1 
ATOM   6844 C CD1 . TYR D 2 23  ? -24.298 15.21   34.875  1   64.36  ? 19  TYR C CD1 1 
ATOM   6845 C CD2 . TYR D 2 23  ? -22.907 17.147  35.105  1   66.85  ? 19  TYR C CD2 1 
ATOM   6846 C CE1 . TYR D 2 23  ? -24.022 14.851  36.19   1   72.31  ? 19  TYR C CE1 1 
ATOM   6847 C CE2 . TYR D 2 23  ? -22.611 16.789  36.416  1   72.67  ? 19  TYR C CE2 1 
ATOM   6848 C CZ  . TYR D 2 23  ? -23.182 15.643  36.961  1   77.75  ? 19  TYR C CZ  1 
ATOM   6849 O OH  . TYR D 2 23  ? -22.968 15.235  38.248  1   90.66  ? 19  TYR C OH  1 
ATOM   6850 N N   . LYS D 2 24  ? -25.338 18.474  30.593  1   49.01  ? 20  LYS C N   1 
ATOM   6851 C CA  . LYS D 2 24  ? -25.203 18.653  29.166  1   46.96  ? 20  LYS C CA  1 
ATOM   6852 C C   . LYS D 2 24  ? -23.773 18.269  28.846  1   48.12  ? 20  LYS C C   1 
ATOM   6853 O O   . LYS D 2 24  ? -22.87  18.612  29.61   1   48.61  ? 20  LYS C O   1 
ATOM   6854 C CB  . LYS D 2 24  ? -25.379 20.122  28.812  1   47.08  ? 20  LYS C CB  1 
ATOM   6855 C CG  . LYS D 2 24  ? -24.943 20.502  27.419  1   48.18  ? 20  LYS C CG  1 
ATOM   6856 C CD  . LYS D 2 24  ? -25.398 21.927  27.141  1   48.61  ? 20  LYS C CD  1 
ATOM   6857 C CE  . LYS D 2 24  ? -24.909 22.358  25.828  1   50.93  ? 20  LYS C CE  1 
ATOM   6858 N NZ  . LYS D 2 24  ? -25.643 23.573  25.506  1   54.01  ? 20  LYS C NZ  1 
ATOM   6859 N N   . ALA D 2 25  ? -23.602 17.524  27.747  1   46.97  ? 21  ALA C N   1 
ATOM   6860 C CA  . ALA D 2 25  ? -22.286 17.036  27.36   1   48.44  ? 21  ALA C CA  1 
ATOM   6861 C C   . ALA D 2 25  ? -22.128 17.081  25.841  1   47.53  ? 21  ALA C C   1 
ATOM   6862 O O   . ALA D 2 25  ? -23.094 17.297  25.112  1   46.9   ? 21  ALA C O   1 
ATOM   6863 C CB  . ALA D 2 25  ? -22.094 15.634  27.906  1   48.48  ? 21  ALA C CB  1 
ATOM   6864 N N   A ARG D 2 26  ? -20.903 16.827  25.389  0.5 48.11  ? 22  ARG C N   1 
ATOM   6865 N N   B ARG D 2 26  ? -20.904 16.867  25.369  0.5 48.59  ? 22  ARG C N   1 
ATOM   6866 C CA  A ARG D 2 26  ? -20.557 16.88   23.983  0.5 48.87  ? 22  ARG C CA  1 
ATOM   6867 C CA  B ARG D 2 26  ? -20.636 16.878  23.944  0.5 49.64  ? 22  ARG C CA  1 
ATOM   6868 C C   A ARG D 2 26  ? -19.765 15.624  23.63   0.5 50.03  ? 22  ARG C C   1 
ATOM   6869 C C   B ARG D 2 26  ? -19.776 15.665  23.602  0.5 50.58  ? 22  ARG C C   1 
ATOM   6870 O O   A ARG D 2 26  ? -18.755 15.337  24.272  0.5 51.3   ? 22  ARG C O   1 
ATOM   6871 O O   B ARG D 2 26  ? -18.737 15.445  24.226  0.5 51.85  ? 22  ARG C O   1 
ATOM   6872 C CB  A ARG D 2 26  ? -19.75  18.161  23.725  0.5 49.95  ? 22  ARG C CB  1 
ATOM   6873 C CB  B ARG D 2 26  ? -20.023 18.217  23.508  0.5 51.4   ? 22  ARG C CB  1 
ATOM   6874 C CG  A ARG D 2 26  ? -18.819 18.176  22.521  0.5 50.76  ? 22  ARG C CG  1 
ATOM   6875 C CG  B ARG D 2 26  ? -19.291 18.226  22.174  0.5 53.16  ? 22  ARG C CG  1 
ATOM   6876 C CD  A ARG D 2 26  ? -18.304 19.587  22.205  0.5 51.59  ? 22  ARG C CD  1 
ATOM   6877 C CD  B ARG D 2 26  ? -18.974 19.625  21.593  0.5 54.58  ? 22  ARG C CD  1 
ATOM   6878 N NE  A ARG D 2 26  ? -17.199 20.015  23.068  0.5 52.79  ? 22  ARG C NE  1 
ATOM   6879 N NE  B ARG D 2 26  ? -19.918 20.043  20.543  0.5 53.84  ? 22  ARG C NE  1 
ATOM   6880 C CZ  A ARG D 2 26  ? -15.968 19.488  23.089  0.5 53.72  ? 22  ARG C CZ  1 
ATOM   6881 C CZ  B ARG D 2 26  ? -20.712 21.119  20.592  0.5 53.71  ? 22  ARG C CZ  1 
ATOM   6882 N NH1 A ARG D 2 26  ? -15.048 20.005  23.873  0.5 55.05  ? 22  ARG C NH1 1 
ATOM   6883 N NH1 B ARG D 2 26  ? -20.733 21.903  21.665  0.5 52.92  ? 22  ARG C NH1 1 
ATOM   6884 N NH2 A ARG D 2 26  ? -15.65  18.454  22.334  0.5 53.34  ? 22  ARG C NH2 1 
ATOM   6885 N NH2 B ARG D 2 26  ? -21.505 21.384  19.566  0.5 53.32  ? 22  ARG C NH2 1 
ATOM   6886 N N   . ASN D 2 27  ? -20.241 14.886  22.615  1   49.64  ? 23  ASN C N   1 
ATOM   6887 C CA  . ASN D 2 27  ? -19.503 13.767  22.053  1   49.86  ? 23  ASN C CA  1 
ATOM   6888 C C   . ASN D 2 27  ? -18.272 14.326  21.347  1   52.05  ? 23  ASN C C   1 
ATOM   6889 O O   . ASN D 2 27  ? -18.412 15.001  20.334  1   52.02  ? 23  ASN C O   1 
ATOM   6890 C CB  . ASN D 2 27  ? -20.372 12.966  21.084  1   48.79  ? 23  ASN C CB  1 
ATOM   6891 C CG  . ASN D 2 27  ? -19.715 11.663  20.646  1   50.72  ? 23  ASN C CG  1 
ATOM   6892 O OD1 . ASN D 2 27  ? -18.574 11.652  20.143  1   49.85  ? 23  ASN C OD1 1 
ATOM   6893 N ND2 . ASN D 2 27  ? -20.42  10.546  20.82   1   49.36  ? 23  ASN C ND2 1 
ATOM   6894 N N   . LYS D 2 28  ? -17.074 14.034  21.864  1   53.89  ? 24  LYS C N   1 
ATOM   6895 C CA  . LYS D 2 28  ? -15.888 14.693  21.342  1   57.52  ? 24  LYS C CA  1 
ATOM   6896 C C   . LYS D 2 28  ? -15.616 14.217  19.921  1   57.14  ? 24  LYS C C   1 
ATOM   6897 O O   . LYS D 2 28  ? -14.949 14.915  19.165  1   60.17  ? 24  LYS C O   1 
ATOM   6898 C CB  . LYS D 2 28  ? -14.632 14.393  22.167  1   62.66  ? 24  LYS C CB  1 
ATOM   6899 C CG  . LYS D 2 28  ? -14.614 14.867  23.616  1   67.08  ? 24  LYS C CG  1 
ATOM   6900 C CD  . LYS D 2 28  ? -13.34  14.463  24.373  1   74.75  ? 24  LYS C CD  1 
ATOM   6901 C CE  . LYS D 2 28  ? -13.587 14.301  25.866  1   77.36  ? 24  LYS C CE  1 
ATOM   6902 N NZ  . LYS D 2 28  ? -12.37  14.193  26.68   1   77.87  ? 24  LYS C NZ  1 
ATOM   6903 N N   . LEU D 2 29  ? -16.082 13.018  19.562  1   54.77  ? 25  LEU C N   1 
ATOM   6904 C CA  . LEU D 2 29  ? -15.774 12.503  18.235  1   55.09  ? 25  LEU C CA  1 
ATOM   6905 C C   . LEU D 2 29  ? -16.804 12.925  17.177  1   54.92  ? 25  LEU C C   1 
ATOM   6906 O O   . LEU D 2 29  ? -16.408 13.246  16.054  1   57.26  ? 25  LEU C O   1 
ATOM   6907 C CB  . LEU D 2 29  ? -15.594 10.993  18.287  1   53.65  ? 25  LEU C CB  1 
ATOM   6908 C CG  . LEU D 2 29  ? -14.246 10.501  18.816  1   53.44  ? 25  LEU C CG  1 
ATOM   6909 C CD1 . LEU D 2 29  ? -14.38  8.995   19.017  1   51.88  ? 25  LEU C CD1 1 
ATOM   6910 C CD2 . LEU D 2 29  ? -13.147 10.893  17.871  1   54.65  ? 25  LEU C CD2 1 
ATOM   6911 N N   . THR D 2 30  ? -18.105 12.914  17.51   1   52.43  ? 26  THR C N   1 
ATOM   6912 C CA  . THR D 2 30  ? -19.152 13.182  16.525  1   52.37  ? 26  THR C CA  1 
ATOM   6913 C C   . THR D 2 30  ? -19.647 14.634  16.563  1   53.58  ? 26  THR C C   1 
ATOM   6914 O O   . THR D 2 30  ? -20.294 15.093  15.618  1   52.73  ? 26  THR C O   1 
ATOM   6915 C CB  . THR D 2 30  ? -20.329 12.218  16.656  1   50.05  ? 26  THR C CB  1 
ATOM   6916 O OG1 . THR D 2 30  ? -20.947 12.484  17.907  1   48.42  ? 26  THR C OG1 1 
ATOM   6917 C CG2 . THR D 2 30  ? -19.912 10.764  16.542  1   50.22  ? 26  THR C CG2 1 
ATOM   6918 N N   . GLY D 2 31  ? -19.356 15.36   17.656  1   55.53  ? 27  GLY C N   1 
ATOM   6919 C CA  . GLY D 2 31  ? -19.819 16.732  17.864  1   56.48  ? 27  GLY C CA  1 
ATOM   6920 C C   . GLY D 2 31  ? -21.243 16.816  18.438  1   57.4   ? 27  GLY C C   1 
ATOM   6921 O O   . GLY D 2 31  ? -21.758 17.907  18.707  1   61.19  ? 27  GLY C O   1 
ATOM   6922 N N   . GLU D 2 32  ? -21.896 15.667  18.645  1   55.82  ? 28  GLU C N   1 
ATOM   6923 C CA  . GLU D 2 32  ? -23.262 15.684  19.153  1   54.29  ? 28  GLU C CA  1 
ATOM   6924 C C   . GLU D 2 32  ? -23.294 16.188  20.599  1   54.46  ? 28  GLU C C   1 
ATOM   6925 O O   . GLU D 2 32  ? -22.527 15.758  21.455  1   54.37  ? 28  GLU C O   1 
ATOM   6926 C CB  . GLU D 2 32  ? -23.859 14.285  19.057  1   52.13  ? 28  GLU C CB  1 
ATOM   6927 C CG  . GLU D 2 32  ? -25.302 14.222  19.536  1   51.14  ? 28  GLU C CG  1 
ATOM   6928 C CD  . GLU D 2 32  ? -25.856 12.808  19.442  1   52.27  ? 28  GLU C CD  1 
ATOM   6929 O OE1 . GLU D 2 32  ? -25.12  11.822  19.692  1   53.66  ? 28  GLU C OE1 1 
ATOM   6930 O OE2 . GLU D 2 32  ? -27.055 12.679  19.154  1   55.08  ? 28  GLU C OE2 1 
ATOM   6931 N N   . VAL D 2 33  ? -24.228 17.101  20.872  1   53.4   ? 29  VAL C N   1 
ATOM   6932 C CA  . VAL D 2 33  ? -24.526 17.571  22.217  1   50.1   ? 29  VAL C CA  1 
ATOM   6933 C C   . VAL D 2 33  ? -25.627 16.684  22.809  1   48.5   ? 29  VAL C C   1 
ATOM   6934 O O   . VAL D 2 33  ? -26.654 16.449  22.167  1   47.76  ? 29  VAL C O   1 
ATOM   6935 C CB  . VAL D 2 33  ? -24.968 19.047  22.114  1   50.34  ? 29  VAL C CB  1 
ATOM   6936 C CG1 . VAL D 2 33  ? -25.437 19.576  23.462  1   48.82  ? 29  VAL C CG1 1 
ATOM   6937 C CG2 . VAL D 2 33  ? -23.876 19.926  21.509  1   50.74  ? 29  VAL C CG2 1 
ATOM   6938 N N   . VAL D 2 34  ? -25.408 16.199  24.038  1   45.62  ? 30  VAL C N   1 
ATOM   6939 C CA  . VAL D 2 34  ? -26.329 15.269  24.667  1   43.52  ? 30  VAL C CA  1 
ATOM   6940 C C   . VAL D 2 34  ? -26.63  15.725  26.098  1   44.38  ? 30  VAL C C   1 
ATOM   6941 O O   . VAL D 2 34  ? -25.955 16.575  26.666  1   46.9   ? 30  VAL C O   1 
ATOM   6942 C CB  . VAL D 2 34  ? -25.733 13.838  24.68   1   42.68  ? 30  VAL C CB  1 
ATOM   6943 C CG1 . VAL D 2 34  ? -25.404 13.338  23.29   1   42.44  ? 30  VAL C CG1 1 
ATOM   6944 C CG2 . VAL D 2 34  ? -24.514 13.687  25.587  1   42.74  ? 30  VAL C CG2 1 
ATOM   6945 N N   . ALA D 2 35  ? -27.617 15.091  26.716  1   44.21  ? 31  ALA C N   1 
ATOM   6946 C CA  . ALA D 2 35  ? -27.776 15.164  28.16   1   44.2   ? 31  ALA C CA  1 
ATOM   6947 C C   . ALA D 2 35  ? -27.429 13.801  28.73   1   43.91  ? 31  ALA C C   1 
ATOM   6948 O O   . ALA D 2 35  ? -27.844 12.779  28.185  1   44.75  ? 31  ALA C O   1 
ATOM   6949 C CB  . ALA D 2 35  ? -29.206 15.541  28.489  1   41.85  ? 31  ALA C CB  1 
ATOM   6950 N N   . LEU D 2 36  ? -26.628 13.802  29.785  1   45.04  ? 32  LEU C N   1 
ATOM   6951 C CA  . LEU D 2 36  ? -26.236 12.587  30.48   1   44.53  ? 32  LEU C CA  1 
ATOM   6952 C C   . LEU D 2 36  ? -26.937 12.558  31.827  1   47.04  ? 32  LEU C C   1 
ATOM   6953 O O   . LEU D 2 36  ? -26.872 13.516  32.6    1   48.17  ? 32  LEU C O   1 
ATOM   6954 C CB  . LEU D 2 36  ? -24.732 12.623  30.706  1   44.51  ? 32  LEU C CB  1 
ATOM   6955 C CG  . LEU D 2 36  ? -23.885 12.622  29.438  1   44.63  ? 32  LEU C CG  1 
ATOM   6956 C CD1 . LEU D 2 36  ? -22.42  12.644  29.831  1   45.72  ? 32  LEU C CD1 1 
ATOM   6957 C CD2 . LEU D 2 36  ? -24.207 11.414  28.583  1   42.91  ? 32  LEU C CD2 1 
ATOM   6958 N N   . LYS D 2 37  ? -27.594 11.436  32.118  1   49.59  ? 33  LYS C N   1 
ATOM   6959 C CA  . LYS D 2 37  ? -28.217 11.222  33.41   1   49.96  ? 33  LYS C CA  1 
ATOM   6960 C C   . LYS D 2 37  ? -27.35  10.215  34.15   1   50.16  ? 33  LYS C C   1 
ATOM   6961 O O   . LYS D 2 37  ? -27.3   9.055   33.77   1   52.01  ? 33  LYS C O   1 
ATOM   6962 C CB  . LYS D 2 37  ? -29.646 10.738  33.132  1   50.93  ? 33  LYS C CB  1 
ATOM   6963 C CG  . LYS D 2 37  ? -30.643 10.914  34.26   1   54.95  ? 33  LYS C CG  1 
ATOM   6964 C CD  . LYS D 2 37  ? -32.068 10.55   33.84   1   56.48  ? 33  LYS C CD  1 
ATOM   6965 C CE  . LYS D 2 37  ? -33.16  10.84   34.822  1   62.74  ? 33  LYS C CE  1 
ATOM   6966 N NZ  . LYS D 2 37  ? -34.408 11.081  34.081  1   63.94  ? 33  LYS C NZ  1 
ATOM   6967 N N   . LYS D 2 38  ? -26.657 10.669  35.185  1   52.43  ? 34  LYS C N   1 
ATOM   6968 C CA  . LYS D 2 38  ? -25.799 9.812   35.989  1   57.35  ? 34  LYS C CA  1 
ATOM   6969 C C   . LYS D 2 38  ? -26.644 9.212   37.113  1   58.23  ? 34  LYS C C   1 
ATOM   6970 O O   . LYS D 2 38  ? -27.16  9.955   37.936  1   63.72  ? 34  LYS C O   1 
ATOM   6971 C CB  . LYS D 2 38  ? -24.643 10.65   36.551  1   59.07  ? 34  LYS C CB  1 
ATOM   6972 C CG  . LYS D 2 38  ? -23.686 9.901   37.473  1   68.28  ? 34  LYS C CG  1 
ATOM   6973 C CD  . LYS D 2 38  ? -22.894 10.698  38.509  1   73.4   ? 34  LYS C CD  1 
ATOM   6974 C CE  . LYS D 2 38  ? -21.992 11.754  37.931  1   76.27  ? 34  LYS C CE  1 
ATOM   6975 N NZ  . LYS D 2 38  ? -20.621 11.358  37.6    1   78.73  ? 34  LYS C NZ  1 
ATOM   6976 N N   . ILE D 2 39  ? -26.759 7.885   37.12   1   57.09  ? 35  ILE C N   1 
ATOM   6977 C CA  . ILE D 2 39  ? -27.526 7.174   38.181  1   55.48  ? 35  ILE C CA  1 
ATOM   6978 C C   . ILE D 2 39  ? -26.525 6.322   38.965  1   58.87  ? 35  ILE C C   1 
ATOM   6979 O O   . ILE D 2 39  ? -25.879 5.455   38.353  1   60.44  ? 35  ILE C O   1 
ATOM   6980 C CB  . ILE D 2 39  ? -28.664 6.333   37.58   1   53.51  ? 35  ILE C CB  1 
ATOM   6981 C CG1 . ILE D 2 39  ? -29.789 7.221   37.08   1   54.31  ? 35  ILE C CG1 1 
ATOM   6982 C CG2 . ILE D 2 39  ? -29.173 5.298   38.581  1   53.56  ? 35  ILE C CG2 1 
ATOM   6983 C CD1 . ILE D 2 39  ? -29.849 7.357   35.573  1   53.75  ? 35  ILE C CD1 1 
ATOM   6984 N N   . ARG D 2 40  ? -26.373 6.612   40.256  1   63.1   ? 36  ARG C N   1 
ATOM   6985 C CA  . ARG D 2 40  ? -25.409 5.859   41.092  1   65.76  ? 36  ARG C CA  1 
ATOM   6986 C C   . ARG D 2 40  ? -26.012 4.497   41.434  1   65.17  ? 36  ARG C C   1 
ATOM   6987 O O   . ARG D 2 40  ? -27.21  4.43    41.756  1   64.11  ? 36  ARG C O   1 
ATOM   6988 C CB  . ARG D 2 40  ? -25.049 6.579   42.39   1   75.49  ? 36  ARG C CB  1 
ATOM   6989 C CG  . ARG D 2 40  ? -23.969 5.864   43.19   1   93.74  ? 36  ARG C CG  1 
ATOM   6990 C CD  . ARG D 2 40  ? -23.518 6.605   44.442  1   110.77 ? 36  ARG C CD  1 
ATOM   6991 N NE  . ARG D 2 40  ? -22.494 5.888   45.21   1   132.95 ? 36  ARG C NE  1 
ATOM   6992 C CZ  . ARG D 2 40  ? -21.192 5.908   44.953  1   139.47 ? 36  ARG C CZ  1 
ATOM   6993 N NH1 . ARG D 2 40  ? -20.649 4.956   44.215  1   134.18 ? 36  ARG C NH1 1 
ATOM   6994 N NH2 . ARG D 2 40  ? -20.438 6.876   45.441  1   129.22 ? 36  ARG C NH2 1 
ATOM   6995 N N   . LEU D 2 41  ? -25.193 3.459   41.343  1   61.31  ? 37  LEU C N   1 
ATOM   6996 C CA  . LEU D 2 41  ? -25.681 2.1     41.645  1   59.57  ? 37  LEU C CA  1 
ATOM   6997 C C   . LEU D 2 41  ? -25.325 1.747   43.091  1   63.77  ? 37  LEU C C   1 
ATOM   6998 O O   . LEU D 2 41  ? -24.148 1.878   43.463  1   69.31  ? 37  LEU C O   1 
ATOM   6999 C CB  . LEU D 2 41  ? -25.104 1.128   40.621  1   56.18  ? 37  LEU C CB  1 
ATOM   7000 C CG  . LEU D 2 41  ? -25.397 1.46    39.156  1   53.77  ? 37  LEU C CG  1 
ATOM   7001 C CD1 . LEU D 2 41  ? -24.782 0.424   38.238  1   51.96  ? 37  LEU C CD1 1 
ATOM   7002 C CD2 . LEU D 2 41  ? -26.892 1.561   38.926  1   51.96  ? 37  LEU C CD2 1 
ATOM   7003 N N   . ASP D 2 42  ? -26.321 1.366   43.876  1   63.39  ? 38  ASP C N   1 
ATOM   7004 C CA  . ASP D 2 42  ? -26.15  0.968   45.261  1   67.98  ? 38  ASP C CA  1 
ATOM   7005 C C   . ASP D 2 42  ? -25.575 -0.451  45.305  1   63.2   ? 38  ASP C C   1 
ATOM   7006 O O   . ASP D 2 42  ? -26.294 -1.399  45.617  1   61.68  ? 38  ASP C O   1 
ATOM   7007 C CB  . ASP D 2 42  ? -27.466 1.179   46.008  1   72.87  ? 38  ASP C CB  1 
ATOM   7008 C CG  . ASP D 2 42  ? -27.9   2.635   46.133  1   76.4   ? 38  ASP C CG  1 
ATOM   7009 O OD1 . ASP D 2 42  ? -27.087 3.433   46.681  1   79.98  ? 38  ASP C OD1 1 
ATOM   7010 O OD2 . ASP D 2 42  ? -29.032 2.969   45.676  1   72.8   ? 38  ASP C OD2 1 
ATOM   7011 N N   . THR D 2 43  ? -24.276 -0.574  45.02   1   59.96  ? 39  THR C N   1 
ATOM   7012 C CA  . THR D 2 43  ? -23.667 -1.858  44.698  1   58.96  ? 39  THR C CA  1 
ATOM   7013 C C   . THR D 2 43  ? -23.499 -2.76   45.915  1   58.59  ? 39  THR C C   1 
ATOM   7014 O O   . THR D 2 43  ? -23.238 -3.933  45.727  1   60.76  ? 39  THR C O   1 
ATOM   7015 C CB  . THR D 2 43  ? -22.332 -1.679  43.958  1   60.14  ? 39  THR C CB  1 
ATOM   7016 O OG1 . THR D 2 43  ? -21.368 -1.048  44.805  1   59.07  ? 39  THR C OG1 1 
ATOM   7017 C CG2 . THR D 2 43  ? -22.517 -0.899  42.663  1   57.77  ? 39  THR C CG2 1 
ATOM   7018 N N   . GLU D 2 44  ? -23.599 -2.234  47.14   1   57.59  ? 40  GLU C N   1 
ATOM   7019 C CA  . GLU D 2 44  ? -23.556 -3.11   48.298  1   58.63  ? 40  GLU C CA  1 
ATOM   7020 C C   . GLU D 2 44  ? -24.912 -3.202  48.998  1   57.85  ? 40  GLU C C   1 
ATOM   7021 O O   . GLU D 2 44  ? -25.017 -3.899  50.003  1   59.86  ? 40  GLU C O   1 
ATOM   7022 C CB  . GLU D 2 44  ? -22.565 -2.652  49.366  1   60.88  ? 40  GLU C CB  1 
ATOM   7023 C CG  . GLU D 2 44  ? -21.116 -2.674  48.899  1   62.42  ? 40  GLU C CG  1 
ATOM   7024 C CD  . GLU D 2 44  ? -20.799 -1.625  47.85   1   61.1   ? 40  GLU C CD  1 
ATOM   7025 O OE1 . GLU D 2 44  ? -20.37  -2.053  46.781  1   60.79  ? 40  GLU C OE1 1 
ATOM   7026 O OE2 . GLU D 2 44  ? -20.992 -0.413  48.055  1   61.54  ? 40  GLU C OE2 1 
ATOM   7027 N N   . THR D 2 45  ? -25.935 -2.499  48.503  1   55.52  ? 41  THR C N   1 
ATOM   7028 C CA  . THR D 2 45  ? -27.189 -2.394  49.241  1   56.45  ? 41  THR C CA  1 
ATOM   7029 C C   . THR D 2 45  ? -28.39  -2.7    48.349  1   54.89  ? 41  THR C C   1 
ATOM   7030 O O   . THR D 2 45  ? -28.895 -3.805  48.441  1   56     ? 41  THR C O   1 
ATOM   7031 C CB  . THR D 2 45  ? -27.307 -1.076  50.021  1   57     ? 41  THR C CB  1 
ATOM   7032 O OG1 . THR D 2 45  ? -27.319 0.047   49.143  1   55.33  ? 41  THR C OG1 1 
ATOM   7033 C CG2 . THR D 2 45  ? -26.168 -0.883  51.008  1   59.89  ? 41  THR C CG2 1 
ATOM   7034 N N   . GLU D 2 46  ? -28.828 -1.768  47.485  1   53.39  ? 42  GLU C N   1 
ATOM   7035 C CA  . GLU D 2 46  ? -30.102 -1.942  46.809  1   52.88  ? 42  GLU C CA  1 
ATOM   7036 C C   . GLU D 2 46  ? -29.945 -2.209  45.316  1   50.5   ? 42  GLU C C   1 
ATOM   7037 O O   . GLU D 2 46  ? -30.934 -2.55   44.687  1   48.47  ? 42  GLU C O   1 
ATOM   7038 C CB  . GLU D 2 46  ? -31.108 -0.828  47.094  1   54.61  ? 42  GLU C CB  1 
ATOM   7039 C CG  . GLU D 2 46  ? -31.585 -0.835  48.552  1   63.65  ? 42  GLU C CG  1 
ATOM   7040 C CD  . GLU D 2 46  ? -31.862 -2.148  49.321  1   70.59  ? 42  GLU C CD  1 
ATOM   7041 O OE1 . GLU D 2 46  ? -32.63  -3.076  48.916  1   70.07  ? 42  GLU C OE1 1 
ATOM   7042 O OE2 . GLU D 2 46  ? -31.312 -2.24   50.447  1   82.81  ? 42  GLU C OE2 1 
ATOM   7043 N N   . GLY D 2 47  ? -28.749 -2.022  44.734  1   49.28  ? 43  GLY C N   1 
ATOM   7044 C CA  . GLY D 2 47  ? -28.553 -2.305  43.319  1   46.69  ? 43  GLY C CA  1 
ATOM   7045 C C   . GLY D 2 47  ? -29.187 -1.233  42.45   1   45.65  ? 43  GLY C C   1 
ATOM   7046 O O   . GLY D 2 47  ? -29.192 -0.063  42.804  1   47.31  ? 43  GLY C O   1 
ATOM   7047 N N   . VAL D 2 48  ? -29.712 -1.617  41.287  1   43.81  ? 44  VAL C N   1 
ATOM   7048 C CA  . VAL D 2 48  ? -30.173 -0.631  40.333  1   42.31  ? 44  VAL C CA  1 
ATOM   7049 C C   . VAL D 2 48  ? -31.566 -0.184  40.761  1   43.72  ? 44  VAL C C   1 
ATOM   7050 O O   . VAL D 2 48  ? -32.437 -1.004  41.033  1   43.98  ? 44  VAL C O   1 
ATOM   7051 C CB  . VAL D 2 48  ? -30.211 -1.231  38.918  1   40.57  ? 44  VAL C CB  1 
ATOM   7052 C CG1 . VAL D 2 48  ? -30.583 -0.201  37.882  1   38.29  ? 44  VAL C CG1 1 
ATOM   7053 C CG2 . VAL D 2 48  ? -28.905 -1.93   38.572  1   41.29  ? 44  VAL C CG2 1 
ATOM   7054 N N   . PRO D 2 49  ? -31.82  1.134   40.861  1   44.71  ? 45  PRO C N   1 
ATOM   7055 C CA  . PRO D 2 49  ? -33.115 1.617   41.334  1   44.15  ? 45  PRO C CA  1 
ATOM   7056 C C   . PRO D 2 49  ? -34.232 1.276   40.355  1   44.99  ? 45  PRO C C   1 
ATOM   7057 O O   . PRO D 2 49  ? -34.055 1.315   39.131  1   44.75  ? 45  PRO C O   1 
ATOM   7058 C CB  . PRO D 2 49  ? -32.96  3.122   41.585  1   43.76  ? 45  PRO C CB  1 
ATOM   7059 C CG  . PRO D 2 49  ? -31.559 3.466   41.103  1   44.92  ? 45  PRO C CG  1 
ATOM   7060 C CD  . PRO D 2 49  ? -30.836 2.206   40.625  1   45.07  ? 45  PRO C CD  1 
ATOM   7061 N N   . SER D 2 50  ? -35.387 0.907   40.929  1   45.81  ? 46  SER C N   1 
ATOM   7062 C CA  . SER D 2 50  ? -36.533 0.5     40.138  1   45.56  ? 46  SER C CA  1 
ATOM   7063 C C   . SER D 2 50  ? -36.944 1.628   39.205  1   43.8   ? 46  SER C C   1 
ATOM   7064 O O   . SER D 2 50  ? -37.362 1.397   38.066  1   43.54  ? 46  SER C O   1 
ATOM   7065 C CB  . SER D 2 50  ? -37.655 0.046   41.037  1   49.4   ? 46  SER C CB  1 
ATOM   7066 O OG  . SER D 2 50  ? -38.195 1.133   41.77   1   51.67  ? 46  SER C OG  1 
ATOM   7067 N N   . THR D 2 51  ? -36.769 2.86    39.685  1   45.55  ? 47  THR C N   1 
ATOM   7068 C CA  . THR D 2 51  ? -36.994 4.073   38.893  1   46.26  ? 47  THR C CA  1 
ATOM   7069 C C   . THR D 2 51  ? -36.274 3.974   37.553  1   45.04  ? 47  THR C C   1 
ATOM   7070 O O   . THR D 2 51  ? -36.832 4.332   36.523  1   44.48  ? 47  THR C O   1 
ATOM   7071 C CB  . THR D 2 51  ? -36.409 5.27    39.623  1   48.84  ? 47  THR C CB  1 
ATOM   7072 O OG1 . THR D 2 51  ? -37.378 5.609   40.602  1   53.73  ? 47  THR C OG1 1 
ATOM   7073 C CG2 . THR D 2 51  ? -36.523 6.476   38.729  1   51.59  ? 47  THR C CG2 1 
ATOM   7074 N N   . ALA D 2 52  ? -35.011 3.53    37.606  1   43.14  ? 48  ALA C N   1 
ATOM   7075 C CA  . ALA D 2 52  ? -34.17  3.469   36.433  1   42.07  ? 48  ALA C CA  1 
ATOM   7076 C C   . ALA D 2 52  ? -34.558 2.27    35.564  1   41.84  ? 48  ALA C C   1 
ATOM   7077 O O   . ALA D 2 52  ? -34.529 2.363   34.339  1   40.85  ? 48  ALA C O   1 
ATOM   7078 C CB  . ALA D 2 52  ? -32.711 3.427   36.873  1   42.37  ? 48  ALA C CB  1 
ATOM   7079 N N   . ILE D 2 53  ? -34.888 1.137   36.195  1   41.89  ? 49  ILE C N   1 
ATOM   7080 C CA  . ILE D 2 53  ? -35.311 -0.041  35.456  1   42.33  ? 49  ILE C CA  1 
ATOM   7081 C C   . ILE D 2 53  ? -36.559 0.271   34.616  1   44.59  ? 49  ILE C C   1 
ATOM   7082 O O   . ILE D 2 53  ? -36.64  -0.124  33.443  1   44.22  ? 49  ILE C O   1 
ATOM   7083 C CB  . ILE D 2 53  ? -35.52  -1.206  36.433  1   41.48  ? 49  ILE C CB  1 
ATOM   7084 C CG1 . ILE D 2 53  ? -34.198 -1.735  36.901  1   40.47  ? 49  ILE C CG1 1 
ATOM   7085 C CG2 . ILE D 2 53  ? -36.399 -2.309  35.826  1   40.75  ? 49  ILE C CG2 1 
ATOM   7086 C CD1 . ILE D 2 53  ? -34.312 -2.445  38.235  1   41.71  ? 49  ILE C CD1 1 
ATOM   7087 N N   . ARG D 2 54  ? -37.502 1.03    35.195  1   43.68  ? 50  ARG C N   1 
ATOM   7088 C CA  . ARG D 2 54  ? -38.69  1.413   34.447  1   43.34  ? 50  ARG C CA  1 
ATOM   7089 C C   . ARG D 2 54  ? -38.355 2.455   33.385  1   43.94  ? 50  ARG C C   1 
ATOM   7090 O O   . ARG D 2 54  ? -38.776 2.321   32.246  1   46.4   ? 50  ARG C O   1 
ATOM   7091 C CB  . ARG D 2 54  ? -39.799 1.902   35.385  1   42.46  ? 50  ARG C CB  1 
ATOM   7092 C CG  . ARG D 2 54  ? -40.468 0.797   36.193  1   43.68  ? 50  ARG C CG  1 
ATOM   7093 C CD  . ARG D 2 54  ? -41.469 1.407   37.149  1   44.58  ? 50  ARG C CD  1 
ATOM   7094 N NE  . ARG D 2 54  ? -42.141 0.377   37.935  1   44.58  ? 50  ARG C NE  1 
ATOM   7095 C CZ  . ARG D 2 54  ? -42.937 0.619   38.968  1   45.7   ? 50  ARG C CZ  1 
ATOM   7096 N NH1 . ARG D 2 54  ? -43.219 1.854   39.352  1   43.59  ? 50  ARG C NH1 1 
ATOM   7097 N NH2 . ARG D 2 54  ? -43.454 -0.398  39.625  1   46.51  ? 50  ARG C NH2 1 
ATOM   7098 N N   . GLU D 2 55  ? -37.638 3.521   33.752  1   44.68  ? 51  GLU C N   1 
ATOM   7099 C CA  . GLU D 2 55  ? -37.35  4.547   32.765  1   45.22  ? 51  GLU C CA  1 
ATOM   7100 C C   . GLU D 2 55  ? -36.651 3.951   31.531  1   43.79  ? 51  GLU C C   1 
ATOM   7101 O O   . GLU D 2 55  ? -37.066 4.201   30.407  1   43.09  ? 51  GLU C O   1 
ATOM   7102 C CB  . GLU D 2 55  ? -36.598 5.737   33.363  1   45.76  ? 51  GLU C CB  1 
ATOM   7103 C CG  . GLU D 2 55  ? -36.077 6.664   32.266  1   49.87  ? 51  GLU C CG  1 
ATOM   7104 C CD  . GLU D 2 55  ? -35.882 8.144   32.539  1   51.82  ? 51  GLU C CD  1 
ATOM   7105 O OE1 . GLU D 2 55  ? -35.141 8.452   33.473  1   45.82  ? 51  GLU C OE1 1 
ATOM   7106 O OE2 . GLU D 2 55  ? -36.491 8.995   31.806  1   59.77  ? 51  GLU C OE2 1 
ATOM   7107 N N   . ILE D 2 56  ? -35.572 3.19    31.736  1   42.74  ? 52  ILE C N   1 
ATOM   7108 C CA  . ILE D 2 56  ? -34.736 2.714   30.647  1   42.59  ? 52  ILE C CA  1 
ATOM   7109 C C   . ILE D 2 56  ? -35.556 1.768   29.772  1   43.89  ? 52  ILE C C   1 
ATOM   7110 O O   . ILE D 2 56  ? -35.562 1.911   28.543  1   47.12  ? 52  ILE C O   1 
ATOM   7111 C CB  . ILE D 2 56  ? -33.44  2.043   31.17   1   42.54  ? 52  ILE C CB  1 
ATOM   7112 C CG1 . ILE D 2 56  ? -32.483 3.04    31.824  1   41.05  ? 52  ILE C CG1 1 
ATOM   7113 C CG2 . ILE D 2 56  ? -32.733 1.329   30.02   1   42.83  ? 52  ILE C CG2 1 
ATOM   7114 C CD1 . ILE D 2 56  ? -31.585 2.471   32.91   1   42.28  ? 52  ILE C CD1 1 
ATOM   7115 N N   . SER D 2 57  ? -36.236 0.799   30.403  1   44.26  ? 53  SER C N   1 
ATOM   7116 C CA  . SER D 2 57  ? -36.948 -0.264  29.693  1   44.88  ? 53  SER C CA  1 
ATOM   7117 C C   . SER D 2 57  ? -38.07  0.304   28.84   1   46.2   ? 53  SER C C   1 
ATOM   7118 O O   . SER D 2 57  ? -38.231 -0.126  27.702  1   47.48  ? 53  SER C O   1 
ATOM   7119 C CB  . SER D 2 57  ? -37.465 -1.355  30.612  1   46.16  ? 53  SER C CB  1 
ATOM   7120 O OG  . SER D 2 57  ? -38.372 -0.82   31.57   1   48.7   ? 53  SER C OG  1 
ATOM   7121 N N   . LEU D 2 58  ? -38.802 1.296   29.382  1   48.86  ? 54  LEU C N   1 
ATOM   7122 C CA  . LEU D 2 58  ? -39.946 1.891   28.695  1   49.54  ? 54  LEU C CA  1 
ATOM   7123 C C   . LEU D 2 58  ? -39.482 2.83    27.578  1   51.23  ? 54  LEU C C   1 
ATOM   7124 O O   . LEU D 2 58  ? -40.059 2.83    26.49   1   57.14  ? 54  LEU C O   1 
ATOM   7125 C CB  . LEU D 2 58  ? -40.903 2.544   29.687  1   47.83  ? 54  LEU C CB  1 
ATOM   7126 C CG  . LEU D 2 58  ? -41.393 1.61    30.803  1   50.76  ? 54  LEU C CG  1 
ATOM   7127 C CD1 . LEU D 2 58  ? -42.235 2.296   31.878  1   45.71  ? 54  LEU C CD1 1 
ATOM   7128 C CD2 . LEU D 2 58  ? -42.135 0.433   30.199  1   49.32  ? 54  LEU C CD2 1 
ATOM   7129 N N   . LEU D 2 59  ? -38.408 3.59    27.814  1   49.04  ? 55  LEU C N   1 
ATOM   7130 C CA  . LEU D 2 59  ? -37.902 4.504   26.799  1   48.57  ? 55  LEU C CA  1 
ATOM   7131 C C   . LEU D 2 59  ? -37.246 3.747   25.647  1   51.33  ? 55  LEU C C   1 
ATOM   7132 O O   . LEU D 2 59  ? -37.122 4.297   24.55   1   58.48  ? 55  LEU C O   1 
ATOM   7133 C CB  . LEU D 2 59  ? -36.915 5.5     27.408  1   47.62  ? 55  LEU C CB  1 
ATOM   7134 C CG  . LEU D 2 59  ? -37.493 6.732   28.1    1   46.7   ? 55  LEU C CG  1 
ATOM   7135 C CD1 . LEU D 2 59  ? -36.372 7.605   28.595  1   47.2   ? 55  LEU C CD1 1 
ATOM   7136 C CD2 . LEU D 2 59  ? -38.366 7.51    27.16   1   47.94  ? 55  LEU C CD2 1 
ATOM   7137 N N   . LYS D 2 60  ? -36.758 2.53    25.9    1   52.29  ? 56  LYS C N   1 
ATOM   7138 C CA  . LYS D 2 60  ? -36.162 1.748   24.827  1   57.87  ? 56  LYS C CA  1 
ATOM   7139 C C   . LYS D 2 60  ? -37.252 1.352   23.828  1   60.3   ? 56  LYS C C   1 
ATOM   7140 O O   . LYS D 2 60  ? -37     1.342   22.629  1   65.35  ? 56  LYS C O   1 
ATOM   7141 C CB  . LYS D 2 60  ? -35.343 0.566   25.358  1   61.46  ? 56  LYS C CB  1 
ATOM   7142 C CG  . LYS D 2 60  ? -33.96  0.951   25.822  1   62.95  ? 56  LYS C CG  1 
ATOM   7143 C CD  . LYS D 2 60  ? -32.977 -0.178  26.124  1   70.44  ? 56  LYS C CD  1 
ATOM   7144 C CE  . LYS D 2 60  ? -32.284 -0.839  24.949  1   69.65  ? 56  LYS C CE  1 
ATOM   7145 N NZ  . LYS D 2 60  ? -32.922 -2.124  24.611  1   68.32  ? 56  LYS C NZ  1 
ATOM   7146 N N   . GLU D 2 61  ? -38.46  1.065   24.334  1   59.36  ? 57  GLU C N   1 
ATOM   7147 C CA  . GLU D 2 61  ? -39.623 0.728   23.528  1   58.3   ? 57  GLU C CA  1 
ATOM   7148 C C   . GLU D 2 61  ? -40.251 1.955   22.875  1   59.55  ? 57  GLU C C   1 
ATOM   7149 O O   . GLU D 2 61  ? -40.768 1.859   21.767  1   67.75  ? 57  GLU C O   1 
ATOM   7150 C CB  . GLU D 2 61  ? -40.727 0.107   24.377  1   57.81  ? 57  GLU C CB  1 
ATOM   7151 C CG  . GLU D 2 61  ? -40.347 -1.279  24.88   1   57.58  ? 57  GLU C CG  1 
ATOM   7152 C CD  . GLU D 2 61  ? -41.522 -2.096  25.358  1   63.17  ? 57  GLU C CD  1 
ATOM   7153 O OE1 . GLU D 2 61  ? -42.689 -1.684  25.101  1   62.96  ? 57  GLU C OE1 1 
ATOM   7154 O OE2 . GLU D 2 61  ? -41.257 -3.163  25.97   1   70     ? 57  GLU C OE2 1 
ATOM   7155 N N   . LEU D 2 62  ? -40.248 3.09    23.568  1   56.43  ? 58  LEU C N   1 
ATOM   7156 C CA  . LEU D 2 62  ? -40.975 4.26    23.097  1   54.41  ? 58  LEU C CA  1 
ATOM   7157 C C   . LEU D 2 62  ? -40.141 5.096   22.122  1   54.16  ? 58  LEU C C   1 
ATOM   7158 O O   . LEU D 2 62  ? -39.431 6.012   22.535  1   60.24  ? 58  LEU C O   1 
ATOM   7159 C CB  . LEU D 2 62  ? -41.423 5.071   24.316  1   52.01  ? 58  LEU C CB  1 
ATOM   7160 C CG  . LEU D 2 62  ? -42.396 4.381   25.278  1   53.88  ? 58  LEU C CG  1 
ATOM   7161 C CD1 . LEU D 2 62  ? -42.813 5.271   26.422  1   49.22  ? 58  LEU C CD1 1 
ATOM   7162 C CD2 . LEU D 2 62  ? -43.609 3.927   24.506  1   53.81  ? 58  LEU C CD2 1 
ATOM   7163 N N   . ASN D 2 63  ? -40.253 4.822   20.821  1   52.36  ? 59  ASN C N   1 
ATOM   7164 C CA  . ASN D 2 63  ? -39.557 5.626   19.834  1   55.36  ? 59  ASN C CA  1 
ATOM   7165 C C   . ASN D 2 63  ? -40.571 6.447   19.048  1   52.33  ? 59  ASN C C   1 
ATOM   7166 O O   . ASN D 2 63  ? -41.271 5.924   18.195  1   56.23  ? 59  ASN C O   1 
ATOM   7167 C CB  . ASN D 2 63  ? -38.522 4.8     19.065  1   67.76  ? 59  ASN C CB  1 
ATOM   7168 C CG  . ASN D 2 63  ? -37.196 4.671   19.81   1   83.48  ? 59  ASN C CG  1 
ATOM   7169 O OD1 . ASN D 2 63  ? -37.105 4.085   20.903  1   75.75  ? 59  ASN C OD1 1 
ATOM   7170 N ND2 . ASN D 2 63  ? -36.133 5.228   19.242  1   95.11  ? 59  ASN C ND2 1 
ATOM   7171 N N   . HIS D 2 64  ? -40.667 7.744   19.354  1   51.31  ? 60  HIS C N   1 
ATOM   7172 C CA  . HIS D 2 64  ? -41.629 8.648   18.723  1   50.29  ? 60  HIS C CA  1 
ATOM   7173 C C   . HIS D 2 64  ? -41.061 10.066  18.756  1   49.07  ? 60  HIS C C   1 
ATOM   7174 O O   . HIS D 2 64  ? -40.39  10.445  19.703  1   49.87  ? 60  HIS C O   1 
ATOM   7175 C CB  . HIS D 2 64  ? -43.004 8.541   19.404  1   49.41  ? 60  HIS C CB  1 
ATOM   7176 C CG  . HIS D 2 64  ? -44.028 9.439   18.804  1   52.02  ? 60  HIS C CG  1 
ATOM   7177 N ND1 . HIS D 2 64  ? -44.129 10.77   19.156  1   52.2   ? 60  HIS C ND1 1 
ATOM   7178 C CD2 . HIS D 2 64  ? -44.978 9.231   17.871  1   52.37  ? 60  HIS C CD2 1 
ATOM   7179 C CE1 . HIS D 2 64  ? -45.094 11.346  18.436  1   52.09  ? 60  HIS C CE1 1 
ATOM   7180 N NE2 . HIS D 2 64  ? -45.635 10.43   17.68   1   52.01  ? 60  HIS C NE2 1 
ATOM   7181 N N   . PRO D 2 65  ? -41.296 10.899  17.725  1   50.08  ? 61  PRO C N   1 
ATOM   7182 C CA  . PRO D 2 65  ? -40.73  12.257  17.669  1   50.34  ? 61  PRO C CA  1 
ATOM   7183 C C   . PRO D 2 65  ? -41.026 13.187  18.837  1   52.35  ? 61  PRO C C   1 
ATOM   7184 O O   . PRO D 2 65  ? -40.384 14.233  18.943  1   53.2   ? 61  PRO C O   1 
ATOM   7185 C CB  . PRO D 2 65  ? -41.317 12.88   16.407  1   50.27  ? 61  PRO C CB  1 
ATOM   7186 C CG  . PRO D 2 65  ? -41.809 11.695  15.6    1   53.11  ? 61  PRO C CG  1 
ATOM   7187 C CD  . PRO D 2 65  ? -42.133 10.562  16.566  1   50.43  ? 61  PRO C CD  1 
ATOM   7188 N N   . ASN D 2 66  ? -42.043 12.837  19.64   1   48.8   ? 62  ASN C N   1 
ATOM   7189 C CA  . ASN D 2 66  ? -42.499 13.686  20.727  1   49.12  ? 62  ASN C CA  1 
ATOM   7190 C C   . ASN D 2 66  ? -42.219 13.015  22.075  1   48.15  ? 62  ASN C C   1 
ATOM   7191 O O   . ASN D 2 66  ? -42.814 13.366  23.092  1   49.21  ? 62  ASN C O   1 
ATOM   7192 C CB  . ASN D 2 66  ? -43.967 14.035  20.541  1   46.6   ? 62  ASN C CB  1 
ATOM   7193 C CG  . ASN D 2 66  ? -44.157 14.91   19.336  1   48.17  ? 62  ASN C CG  1 
ATOM   7194 O OD1 . ASN D 2 66  ? -44.895 14.541  18.418  1   53.34  ? 62  ASN C OD1 1 
ATOM   7195 N ND2 . ASN D 2 66  ? -43.542 16.081  19.333  1   46.98  ? 62  ASN C ND2 1 
ATOM   7196 N N   . ILE D 2 67  ? -41.334 12.015  22.055  1   44.25  ? 63  ILE C N   1 
ATOM   7197 C CA  . ILE D 2 67  ? -40.822 11.396  23.259  1   43.85  ? 63  ILE C CA  1 
ATOM   7198 C C   . ILE D 2 67  ? -39.297 11.506  23.249  1   45.44  ? 63  ILE C C   1 
ATOM   7199 O O   . ILE D 2 67  ? -38.65  11.166  22.247  1   43.95  ? 63  ILE C O   1 
ATOM   7200 C CB  . ILE D 2 67  ? -41.299 9.941   23.334  1   43.01  ? 63  ILE C CB  1 
ATOM   7201 C CG1 . ILE D 2 67  ? -42.855 9.878   23.405  1   43.99  ? 63  ILE C CG1 1 
ATOM   7202 C CG2 . ILE D 2 67  ? -40.628 9.219   24.501  1   40.39  ? 63  ILE C CG2 1 
ATOM   7203 C CD1 . ILE D 2 67  ? -43.402 8.459   23.427  1   43.88  ? 63  ILE C CD1 1 
ATOM   7204 N N   . VAL D 2 68  ? -38.746 11.998  24.372  1   45.37  ? 64  VAL C N   1 
ATOM   7205 C CA  . VAL D 2 68  ? -37.311 12.181  24.502  1   44.78  ? 64  VAL C CA  1 
ATOM   7206 C C   . VAL D 2 68  ? -36.626 10.872  24.087  1   45.41  ? 64  VAL C C   1 
ATOM   7207 O O   . VAL D 2 68  ? -37.068 9.776   24.441  1   45.89  ? 64  VAL C O   1 
ATOM   7208 C CB  . VAL D 2 68  ? -36.941 12.646  25.918  1   43.29  ? 64  VAL C CB  1 
ATOM   7209 C CG1 . VAL D 2 68  ? -37.095 11.52   26.942  1   41.83  ? 64  VAL C CG1 1 
ATOM   7210 C CG2 . VAL D 2 68  ? -35.542 13.245  25.966  1   44.56  ? 64  VAL C CG2 1 
ATOM   7211 N N   . LYS D 2 69  ? -35.61  11.012  23.242  1   43.96  ? 65  LYS C N   1 
ATOM   7212 C CA  . LYS D 2 69  ? -34.916 9.879   22.656  1   46.85  ? 65  LYS C CA  1 
ATOM   7213 C C   . LYS D 2 69  ? -33.769 9.473   23.574  1   45.36  ? 65  LYS C C   1 
ATOM   7214 O O   . LYS D 2 69  ? -32.919 10.29   23.926  1   44.25  ? 65  LYS C O   1 
ATOM   7215 C CB  . LYS D 2 69  ? -34.392 10.286  21.275  1   53.14  ? 65  LYS C CB  1 
ATOM   7216 C CG  . LYS D 2 69  ? -34.053 9.149   20.348  1   67.37  ? 65  LYS C CG  1 
ATOM   7217 C CD  . LYS D 2 69  ? -33.803 9.604   18.904  1   88.64  ? 65  LYS C CD  1 
ATOM   7218 C CE  . LYS D 2 69  ? -34.076 8.545   17.846  1   102.07 ? 65  LYS C CE  1 
ATOM   7219 N NZ  . LYS D 2 69  ? -33.597 7.221   18.261  1   100.42 ? 65  LYS C NZ  1 
ATOM   7220 N N   . LEU D 2 70  ? -33.8   8.217   24.011  1   43.2   ? 66  LEU C N   1 
ATOM   7221 C CA  . LEU D 2 70  ? -32.695 7.636   24.745  1   44.67  ? 66  LEU C CA  1 
ATOM   7222 C C   . LEU D 2 70  ? -31.715 7.008   23.737  1   46.31  ? 66  LEU C C   1 
ATOM   7223 O O   . LEU D 2 70  ? -32.08  6.1     22.991  1   47.65  ? 66  LEU C O   1 
ATOM   7224 C CB  . LEU D 2 70  ? -33.256 6.626   25.747  1   41.8   ? 66  LEU C CB  1 
ATOM   7225 C CG  . LEU D 2 70  ? -32.207 5.766   26.461  1   42.37  ? 66  LEU C CG  1 
ATOM   7226 C CD1 . LEU D 2 70  ? -31.373 6.559   27.462  1   39.79  ? 66  LEU C CD1 1 
ATOM   7227 C CD2 . LEU D 2 70  ? -32.878 4.591   27.152  1   43.57  ? 66  LEU C CD2 1 
ATOM   7228 N N   . LEU D 2 71  ? -30.479 7.525   23.68   1   44.44  ? 67  LEU C N   1 
ATOM   7229 C CA  . LEU D 2 71  ? -29.507 7.134   22.658  1   43.12  ? 67  LEU C CA  1 
ATOM   7230 C C   . LEU D 2 71  ? -28.681 5.928   23.107  1   43.01  ? 67  LEU C C   1 
ATOM   7231 O O   . LEU D 2 71  ? -28.261 5.135   22.264  1   43.9   ? 67  LEU C O   1 
ATOM   7232 C CB  . LEU D 2 71  ? -28.575 8.302   22.331  1   42.33  ? 67  LEU C CB  1 
ATOM   7233 C CG  . LEU D 2 71  ? -29.258 9.569   21.818  1   44.15  ? 67  LEU C CG  1 
ATOM   7234 C CD1 . LEU D 2 71  ? -28.261 10.719  21.783  1   44.53  ? 67  LEU C CD1 1 
ATOM   7235 C CD2 . LEU D 2 71  ? -29.922 9.368   20.437  1   43.01  ? 67  LEU C CD2 1 
ATOM   7236 N N   . ASP D 2 72  ? -28.373 5.839   24.416  1   42.39  ? 68  ASP C N   1 
ATOM   7237 C CA  . ASP D 2 72  ? -27.467 4.814   24.896  1   42.45  ? 68  ASP C CA  1 
ATOM   7238 C C   . ASP D 2 72  ? -27.595 4.666   26.409  1   43.46  ? 68  ASP C C   1 
ATOM   7239 O O   . ASP D 2 72  ? -28.11  5.52    27.135  1   41.66  ? 68  ASP C O   1 
ATOM   7240 C CB  . ASP D 2 72  ? -26.032 5.155   24.508  1   44.6   ? 68  ASP C CB  1 
ATOM   7241 C CG  . ASP D 2 72  ? -25.085 3.972   24.369  1   47.3   ? 68  ASP C CG  1 
ATOM   7242 O OD1 . ASP D 2 72  ? -25.515 2.851   24.727  1   50.54  ? 68  ASP C OD1 1 
ATOM   7243 O OD2 . ASP D 2 72  ? -23.938 4.168   23.886  1   46.84  ? 68  ASP C OD2 1 
ATOM   7244 N N   . VAL D 2 73  ? -27.061 3.554   26.893  1   45.47  ? 69  VAL C N   1 
ATOM   7245 C CA  . VAL D 2 73  ? -26.915 3.333   28.315  1   46.45  ? 69  VAL C CA  1 
ATOM   7246 C C   . VAL D 2 73  ? -25.505 2.802   28.485  1   49.61  ? 69  VAL C C   1 
ATOM   7247 O O   . VAL D 2 73  ? -25.169 1.752   27.922  1   53.13  ? 69  VAL C O   1 
ATOM   7248 C CB  . VAL D 2 73  ? -27.942 2.314   28.85   1   45.5   ? 69  VAL C CB  1 
ATOM   7249 C CG1 . VAL D 2 73  ? -27.819 2.134   30.362  1   43.83  ? 69  VAL C CG1 1 
ATOM   7250 C CG2 . VAL D 2 73  ? -29.365 2.663   28.403  1   44.75  ? 69  VAL C CG2 1 
ATOM   7251 N N   . ILE D 2 74  ? -24.693 3.55    29.233  1   50.31  ? 70  ILE C N   1 
ATOM   7252 C CA  . ILE D 2 74  ? -23.298 3.18    29.399  1   54.8   ? 70  ILE C CA  1 
ATOM   7253 C C   . ILE D 2 74  ? -23.087 2.674   30.819  1   55.94  ? 70  ILE C C   1 
ATOM   7254 O O   . ILE D 2 74  ? -23.354 3.378   31.773  1   55.36  ? 70  ILE C O   1 
ATOM   7255 C CB  . ILE D 2 74  ? -22.364 4.342   29.006  1   55.05  ? 70  ILE C CB  1 
ATOM   7256 C CG1 . ILE D 2 74  ? -22.543 4.684   27.53   1   52.79  ? 70  ILE C CG1 1 
ATOM   7257 C CG2 . ILE D 2 74  ? -20.902 4.033   29.345  1   54.72  ? 70  ILE C CG2 1 
ATOM   7258 C CD1 . ILE D 2 74  ? -21.871 5.989   27.148  1   56.32  ? 70  ILE C CD1 1 
ATOM   7259 N N   . HIS D 2 75  ? -22.605 1.44    30.921  1   62.55  ? 71  HIS C N   1 
ATOM   7260 C CA  . HIS D 2 75  ? -22.469 0.743   32.19   1   65.51  ? 71  HIS C CA  1 
ATOM   7261 C C   . HIS D 2 75  ? -21.065 0.956   32.747  1   68.26  ? 71  HIS C C   1 
ATOM   7262 O O   . HIS D 2 75  ? -20.118 1.132   32.004  1   68.54  ? 71  HIS C O   1 
ATOM   7263 C CB  . HIS D 2 75  ? -22.735 -0.756  31.995  1   64.54  ? 71  HIS C CB  1 
ATOM   7264 C CG  . HIS D 2 75  ? -24.126 -1.107  31.579  1   63.8   ? 71  HIS C CG  1 
ATOM   7265 N ND1 . HIS D 2 75  ? -25.041 -1.624  32.474  1   61.34  ? 71  HIS C ND1 1 
ATOM   7266 C CD2 . HIS D 2 75  ? -24.76  -1.025  30.383  1   62.96  ? 71  HIS C CD2 1 
ATOM   7267 C CE1 . HIS D 2 75  ? -26.18  -1.851  31.84   1   62.18  ? 71  HIS C CE1 1 
ATOM   7268 N NE2 . HIS D 2 75  ? -26.04  -1.492  30.571  1   62.29  ? 71  HIS C NE2 1 
ATOM   7269 N N   . THR D 2 76  ? -20.961 1.021   34.072  1   75.19  ? 72  THR C N   1 
ATOM   7270 C CA  . THR D 2 76  ? -19.73  0.725   34.795  1   77.56  ? 72  THR C CA  1 
ATOM   7271 C C   . THR D 2 76  ? -20.157 -0.255  35.891  1   79.23  ? 72  THR C C   1 
ATOM   7272 O O   . THR D 2 76  ? -21.321 -0.696  35.894  1   71.9   ? 72  THR C O   1 
ATOM   7273 C CB  . THR D 2 76  ? -18.986 1.98    35.288  1   75.79  ? 72  THR C CB  1 
ATOM   7274 O OG1 . THR D 2 76  ? -19.696 2.695   36.295  1   79.16  ? 72  THR C OG1 1 
ATOM   7275 C CG2 . THR D 2 76  ? -18.718 3.006   34.197  1   74.19  ? 72  THR C CG2 1 
ATOM   7276 N N   . GLU D 2 77  ? -19.242 -0.615  36.8    1   80.64  ? 73  GLU C N   1 
ATOM   7277 C CA  . GLU D 2 77  ? -19.678 -1.45   37.912  1   81.23  ? 73  GLU C CA  1 
ATOM   7278 C C   . GLU D 2 77  ? -20.394 -0.582  38.954  1   77.16  ? 73  GLU C C   1 
ATOM   7279 O O   . GLU D 2 77  ? -21.252 -1.081  39.682  1   75.47  ? 73  GLU C O   1 
ATOM   7280 C CB  . GLU D 2 77  ? -18.605 -2.415  38.43   1   87.58  ? 73  GLU C CB  1 
ATOM   7281 C CG  . GLU D 2 77  ? -17.264 -1.746  38.707  1   104.48 ? 73  GLU C CG  1 
ATOM   7282 C CD  . GLU D 2 77  ? -16.278 -2.697  39.38   1   126.02 ? 73  GLU C CD  1 
ATOM   7283 O OE1 . GLU D 2 77  ? -15.226 -2.921  38.747  1   135.06 ? 73  GLU C OE1 1 
ATOM   7284 O OE2 . GLU D 2 77  ? -16.537 -3.212  40.504  1   123.79 ? 73  GLU C OE2 1 
ATOM   7285 N N   . ASN D 2 78  ? -20.105 0.735   38.951  1   73.48  ? 74  ASN C N   1 
ATOM   7286 C CA  . ASN D 2 78  ? -20.526 1.669   39.997  1   67.83  ? 74  ASN C CA  1 
ATOM   7287 C C   . ASN D 2 78  ? -21.541 2.72    39.535  1   63.85  ? 74  ASN C C   1 
ATOM   7288 O O   . ASN D 2 78  ? -22.16  3.379   40.372  1   61.64  ? 74  ASN C O   1 
ATOM   7289 C CB  . ASN D 2 78  ? -19.314 2.319   40.644  1   69.49  ? 74  ASN C CB  1 
ATOM   7290 C CG  . ASN D 2 78  ? -18.524 1.3     41.431  1   74.3   ? 74  ASN C CG  1 
ATOM   7291 O OD1 . ASN D 2 78  ? -18.996 0.761   42.449  1   75.63  ? 74  ASN C OD1 1 
ATOM   7292 N ND2 . ASN D 2 78  ? -17.315 1.026   40.965  1   75.95  ? 74  ASN C ND2 1 
ATOM   7293 N N   . LYS D 2 79  ? -21.727 2.885   38.219  1   61.87  ? 75  LYS C N   1 
ATOM   7294 C CA  . LYS D 2 79  ? -22.607 3.936   37.732  1   60.58  ? 75  LYS C CA  1 
ATOM   7295 C C   . LYS D 2 79  ? -23.341 3.53    36.464  1   56.68  ? 75  LYS C C   1 
ATOM   7296 O O   . LYS D 2 79  ? -22.905 2.68    35.692  1   61.33  ? 75  LYS C O   1 
ATOM   7297 C CB  . LYS D 2 79  ? -21.795 5.213   37.501  1   65.96  ? 75  LYS C CB  1 
ATOM   7298 C CG  . LYS D 2 79  ? -21.892 6.198   38.65   1   76.4   ? 75  LYS C CG  1 
ATOM   7299 C CD  . LYS D 2 79  ? -20.655 7.052   38.92   1   84.13  ? 75  LYS C CD  1 
ATOM   7300 C CE  . LYS D 2 79  ? -20.734 7.731   40.268  1   91.61  ? 75  LYS C CE  1 
ATOM   7301 N NZ  . LYS D 2 79  ? -19.579 8.608   40.486  1   99.53  ? 75  LYS C NZ  1 
ATOM   7302 N N   . LEU D 2 80  ? -24.446 4.215   36.224  1   54.03  ? 76  LEU C N   1 
ATOM   7303 C CA  . LEU D 2 80  ? -25.143 4.127   34.951  1   51.38  ? 76  LEU C CA  1 
ATOM   7304 C C   . LEU D 2 80  ? -25.217 5.538   34.372  1   50.29  ? 76  LEU C C   1 
ATOM   7305 O O   . LEU D 2 80  ? -25.504 6.488   35.105  1   50.74  ? 76  LEU C O   1 
ATOM   7306 C CB  . LEU D 2 80  ? -26.537 3.61    35.293  1   51.74  ? 76  LEU C CB  1 
ATOM   7307 C CG  . LEU D 2 80  ? -27.118 2.503   34.415  1   51.19  ? 76  LEU C CG  1 
ATOM   7308 C CD1 . LEU D 2 80  ? -26.115 1.375   34.212  1   53.16  ? 76  LEU C CD1 1 
ATOM   7309 C CD2 . LEU D 2 80  ? -28.388 1.972   35.07   1   48.04  ? 76  LEU C CD2 1 
ATOM   7310 N N   . TYR D 2 81  ? -24.904 5.684   33.078  1   47.57  ? 77  TYR C N   1 
ATOM   7311 C CA  . TYR D 2 81  ? -25.145 6.95    32.419  1   47.66  ? 77  TYR C CA  1 
ATOM   7312 C C   . TYR D 2 81  ? -26.146 6.711   31.294  1   47.97  ? 77  TYR C C   1 
ATOM   7313 O O   . TYR D 2 81  ? -25.869 5.89    30.422  1   48.62  ? 77  TYR C O   1 
ATOM   7314 C CB  . TYR D 2 81  ? -23.854 7.497   31.823  1   49.37  ? 77  TYR C CB  1 
ATOM   7315 C CG  . TYR D 2 81  ? -22.809 7.941   32.824  1   51.51  ? 77  TYR C CG  1 
ATOM   7316 C CD1 . TYR D 2 81  ? -22.806 9.243   33.295  1   54.61  ? 77  TYR C CD1 1 
ATOM   7317 C CD2 . TYR D 2 81  ? -21.807 7.087   33.24   1   52.14  ? 77  TYR C CD2 1 
ATOM   7318 C CE1 . TYR D 2 81  ? -21.839 9.687   34.174  1   56.82  ? 77  TYR C CE1 1 
ATOM   7319 C CE2 . TYR D 2 81  ? -20.834 7.512   34.126  1   56.62  ? 77  TYR C CE2 1 
ATOM   7320 C CZ  . TYR D 2 81  ? -20.853 8.814   34.599  1   60.03  ? 77  TYR C CZ  1 
ATOM   7321 O OH  . TYR D 2 81  ? -19.905 9.268   35.489  1   67.87  ? 77  TYR C OH  1 
ATOM   7322 N N   . LEU D 2 82  ? -27.305 7.387   31.354  1   45.72  ? 78  LEU C N   1 
ATOM   7323 C CA  . LEU D 2 82  ? -28.237 7.399   30.236  1   45.86  ? 78  LEU C CA  1 
ATOM   7324 C C   . LEU D 2 82  ? -27.85  8.556   29.32   1   45.59  ? 78  LEU C C   1 
ATOM   7325 O O   . LEU D 2 82  ? -27.619 9.657   29.793  1   46.87  ? 78  LEU C O   1 
ATOM   7326 C CB  . LEU D 2 82  ? -29.71  7.519   30.649  1   46.21  ? 78  LEU C CB  1 
ATOM   7327 C CG  . LEU D 2 82  ? -30.217 6.841   31.931  1   46.24  ? 78  LEU C CG  1 
ATOM   7328 C CD1 . LEU D 2 82  ? -31.683 6.557   31.741  1   44.84  ? 78  LEU C CD1 1 
ATOM   7329 C CD2 . LEU D 2 82  ? -29.476 5.61    32.423  1   50.46  ? 78  LEU C CD2 1 
ATOM   7330 N N   . VAL D 2 83  ? -27.715 8.282   28.024  1   44.93  ? 79  VAL C N   1 
ATOM   7331 C CA  . VAL D 2 83  ? -27.4   9.308   27.053  1   43.99  ? 79  VAL C CA  1 
ATOM   7332 C C   . VAL D 2 83  ? -28.692 9.651   26.318  1   43.67  ? 79  VAL C C   1 
ATOM   7333 O O   . VAL D 2 83  ? -29.343 8.761   25.76   1   42.1   ? 79  VAL C O   1 
ATOM   7334 C CB  . VAL D 2 83  ? -26.303 8.823   26.087  1   43.89  ? 79  VAL C CB  1 
ATOM   7335 C CG1 . VAL D 2 83  ? -25.864 9.917   25.125  1   43.48  ? 79  VAL C CG1 1 
ATOM   7336 C CG2 . VAL D 2 83  ? -25.112 8.284   26.857  1   44.13  ? 79  VAL C CG2 1 
ATOM   7337 N N   . PHE D 2 84  ? -29.052 10.946  26.351  1   44.1   ? 80  PHE C N   1 
ATOM   7338 C CA  . PHE D 2 84  ? -30.29  11.478  25.774  1   43.06  ? 80  PHE C CA  1 
ATOM   7339 C C   . PHE D 2 84  ? -29.921 12.514  24.724  1   44.01  ? 80  PHE C C   1 
ATOM   7340 O O   . PHE D 2 84  ? -28.882 13.158  24.84   1   45.62  ? 80  PHE C O   1 
ATOM   7341 C CB  . PHE D 2 84  ? -31.146 12.208  26.814  1   41.77  ? 80  PHE C CB  1 
ATOM   7342 C CG  . PHE D 2 84  ? -31.845 11.313  27.819  1   40.09  ? 80  PHE C CG  1 
ATOM   7343 C CD1 . PHE D 2 84  ? -33.052 10.708  27.506  1   39.89  ? 80  PHE C CD1 1 
ATOM   7344 C CD2 . PHE D 2 84  ? -31.303 11.079  29.069  1   41.44  ? 80  PHE C CD2 1 
ATOM   7345 C CE1 . PHE D 2 84  ? -33.694 9.872   28.413  1   39.55  ? 80  PHE C CE1 1 
ATOM   7346 C CE2 . PHE D 2 84  ? -31.95  10.251  29.984  1   40.59  ? 80  PHE C CE2 1 
ATOM   7347 C CZ  . PHE D 2 84  ? -33.14  9.653   29.655  1   40.15  ? 80  PHE C CZ  1 
ATOM   7348 N N   . GLU D 2 85  ? -30.754 12.646  23.692  1   45.02  ? 81  GLU C N   1 
ATOM   7349 C CA  . GLU D 2 85  ? -30.627 13.763  22.77   1   46.15  ? 81  GLU C CA  1 
ATOM   7350 C C   . GLU D 2 85  ? -30.778 15.006  23.64   1   47.25  ? 81  GLU C C   1 
ATOM   7351 O O   . GLU D 2 85  ? -31.432 14.955  24.673  1   53.5   ? 81  GLU C O   1 
ATOM   7352 C CB  . GLU D 2 85  ? -31.73  13.695  21.718  1   48.15  ? 81  GLU C CB  1 
ATOM   7353 C CG  . GLU D 2 85  ? -33.092 14.029  22.335  1   55.24  ? 81  GLU C CG  1 
ATOM   7354 C CD  . GLU D 2 85  ? -34.272 14.167  21.38   1   61.78  ? 81  GLU C CD  1 
ATOM   7355 O OE1 . GLU D 2 85  ? -34.214 14.959  20.388  1   61.07  ? 81  GLU C OE1 1 
ATOM   7356 O OE2 . GLU D 2 85  ? -35.288 13.495  21.682  1   65.11  ? 81  GLU C OE2 1 
ATOM   7357 N N   . PHE D 2 86  ? -30.141 16.109  23.27   1   46.15  ? 82  PHE C N   1 
ATOM   7358 C CA  . PHE D 2 86  ? -30.186 17.28   24.123  1   45.99  ? 82  PHE C CA  1 
ATOM   7359 C C   . PHE D 2 86  ? -31.301 18.175  23.622  1   46.8   ? 82  PHE C C   1 
ATOM   7360 O O   . PHE D 2 86  ? -31.39  18.399  22.421  1   47.52  ? 82  PHE C O   1 
ATOM   7361 C CB  . PHE D 2 86  ? -28.876 18.068  24.061  1   46.88  ? 82  PHE C CB  1 
ATOM   7362 C CG  . PHE D 2 86  ? -28.967 19.42   24.732  1   47.87  ? 82  PHE C CG  1 
ATOM   7363 C CD1 . PHE D 2 86  ? -28.943 19.515  26.127  1   47.87  ? 82  PHE C CD1 1 
ATOM   7364 C CD2 . PHE D 2 86  ? -29.086 20.589  23.962  1   48.63  ? 82  PHE C CD2 1 
ATOM   7365 C CE1 . PHE D 2 86  ? -29.051 20.769  26.742  1   49.22  ? 82  PHE C CE1 1 
ATOM   7366 C CE2 . PHE D 2 86  ? -29.187 21.838  24.576  1   48.73  ? 82  PHE C CE2 1 
ATOM   7367 C CZ  . PHE D 2 86  ? -29.181 21.923  25.966  1   49.39  ? 82  PHE C CZ  1 
ATOM   7368 N N   . LEU D 2 87  ? -32.145 18.651  24.537  1   47.02  ? 83  LEU C N   1 
ATOM   7369 C CA  . LEU D 2 87  ? -33.145 19.636  24.173  1   47.62  ? 83  LEU C CA  1 
ATOM   7370 C C   . LEU D 2 87  ? -32.861 20.897  24.963  1   50.25  ? 83  LEU C C   1 
ATOM   7371 O O   . LEU D 2 87  ? -32.434 20.815  26.106  1   49.08  ? 83  LEU C O   1 
ATOM   7372 C CB  . LEU D 2 87  ? -34.512 19.034  24.426  1   46.96  ? 83  LEU C CB  1 
ATOM   7373 C CG  . LEU D 2 87  ? -34.803 17.843  23.509  1   48.79  ? 83  LEU C CG  1 
ATOM   7374 C CD1 . LEU D 2 87  ? -35.858 16.923  24.028  1   49.27  ? 83  LEU C CD1 1 
ATOM   7375 C CD2 . LEU D 2 87  ? -35.155 18.298  22.118  1   49.82  ? 83  LEU C CD2 1 
ATOM   7376 N N   . HIS D 2 88  ? -33.039 22.034  24.283  1   55.4   ? 84  HIS C N   1 
ATOM   7377 C CA  . HIS D 2 88  ? -32.638 23.367  24.712  1   61.5   ? 84  HIS C CA  1 
ATOM   7378 C C   . HIS D 2 88  ? -33.163 23.763  26.098  1   57.02  ? 84  HIS C C   1 
ATOM   7379 O O   . HIS D 2 88  ? -32.407 24.346  26.878  1   56.2   ? 84  HIS C O   1 
ATOM   7380 C CB  . HIS D 2 88  ? -33.084 24.408  23.685  1   71.21  ? 84  HIS C CB  1 
ATOM   7381 C CG  . HIS D 2 88  ? -32.605 25.781  24.024  1   92.07  ? 84  HIS C CG  1 
ATOM   7382 N ND1 . HIS D 2 88  ? -33.41  26.787  24.523  1   98.39  ? 84  HIS C ND1 1 
ATOM   7383 C CD2 . HIS D 2 88  ? -31.371 26.311  23.892  1   103.25 ? 84  HIS C CD2 1 
ATOM   7384 C CE1 . HIS D 2 88  ? -32.677 27.886  24.697  1   110.13 ? 84  HIS C CE1 1 
ATOM   7385 N NE2 . HIS D 2 88  ? -31.436 27.619  24.316  1   114.06 ? 84  HIS C NE2 1 
ATOM   7386 N N   . GLN D 2 89  ? -34.458 23.537  26.38   1   52.68  ? 85  GLN C N   1 
ATOM   7387 C CA  . GLN D 2 89  ? -34.971 23.749  27.733  1   54.05  ? 85  GLN C CA  1 
ATOM   7388 C C   . GLN D 2 89  ? -36.35  23.119  27.944  1   51.22  ? 85  GLN C C   1 
ATOM   7389 O O   . GLN D 2 89  ? -36.967 22.603  27.024  1   50.8   ? 85  GLN C O   1 
ATOM   7390 C CB  . GLN D 2 89  ? -34.969 25.202  28.217  1   56.16  ? 85  GLN C CB  1 
ATOM   7391 C CG  . GLN D 2 89  ? -35.877 26.132  27.42   1   60.98  ? 85  GLN C CG  1 
ATOM   7392 C CD  . GLN D 2 89  ? -35.778 27.569  27.898  1   69.48  ? 85  GLN C CD  1 
ATOM   7393 O OE1 . GLN D 2 89  ? -35.04  27.897  28.837  1   69.47  ? 85  GLN C OE1 1 
ATOM   7394 N NE2 . GLN D 2 89  ? -36.537 28.45   27.265  1   69.75  ? 85  GLN C NE2 1 
ATOM   7395 N N   . ASP D 2 90  ? -36.836 23.199  29.184  1   50.31  ? 86  ASP C N   1 
ATOM   7396 C CA  . ASP D 2 90  ? -38.121 22.639  29.567  1   50.22  ? 86  ASP C CA  1 
ATOM   7397 C C   . ASP D 2 90  ? -39.193 23.725  29.508  1   49.23  ? 86  ASP C C   1 
ATOM   7398 O O   . ASP D 2 90  ? -38.887 24.915  29.594  1   49.26  ? 86  ASP C O   1 
ATOM   7399 C CB  . ASP D 2 90  ? -38.05  22.001  30.945  1   48.87  ? 86  ASP C CB  1 
ATOM   7400 C CG  . ASP D 2 90  ? -37.865 22.987  32.079  1   50.54  ? 86  ASP C CG  1 
ATOM   7401 O OD1 . ASP D 2 90  ? -38.801 23.735  32.386  1   51.31  ? 86  ASP C OD1 1 
ATOM   7402 O OD2 . ASP D 2 90  ? -36.765 23.022  32.629  1   59.74  ? 86  ASP C OD2 1 
ATOM   7403 N N   . LEU D 2 91  ? -40.455 23.283  29.462  1   47.2   ? 87  LEU C N   1 
ATOM   7404 C CA  . LEU D 2 91  ? -41.575 24.161  29.155  1   46.88  ? 87  LEU C CA  1 
ATOM   7405 C C   . LEU D 2 91  ? -41.777 25.143  30.307  1   47.44  ? 87  LEU C C   1 
ATOM   7406 O O   . LEU D 2 91  ? -42.182 26.29   30.085  1   49.09  ? 87  LEU C O   1 
ATOM   7407 C CB  . LEU D 2 91  ? -42.83  23.328  28.862  1   44.78  ? 87  LEU C CB  1 
ATOM   7408 C CG  . LEU D 2 91  ? -44.108 24.119  28.518  1   43.67  ? 87  LEU C CG  1 
ATOM   7409 C CD1 . LEU D 2 91  ? -44.018 24.87   27.208  1   42.11  ? 87  LEU C CD1 1 
ATOM   7410 C CD2 . LEU D 2 91  ? -45.303 23.178  28.469  1   42.02  ? 87  LEU C CD2 1 
ATOM   7411 N N   . LYS D 2 92  ? -41.472 24.702  31.535  1   46.32  ? 88  LYS C N   1 
ATOM   7412 C CA  . LYS D 2 92  ? -41.584 25.591  32.678  1   47.89  ? 88  LYS C CA  1 
ATOM   7413 C C   . LYS D 2 92  ? -40.631 26.772  32.511  1   49.32  ? 88  LYS C C   1 
ATOM   7414 O O   . LYS D 2 92  ? -41.008 27.909  32.78   1   51.46  ? 88  LYS C O   1 
ATOM   7415 C CB  . LYS D 2 92  ? -41.404 24.846  33.999  1   49.06  ? 88  LYS C CB  1 
ATOM   7416 C CG  . LYS D 2 92  ? -41.253 25.715  35.229  1   54.11  ? 88  LYS C CG  1 
ATOM   7417 C CD  . LYS D 2 92  ? -42.371 26.713  35.535  1   62.06  ? 88  LYS C CD  1 
ATOM   7418 C CE  . LYS D 2 92  ? -43.685 26.03   35.699  1   69.66  ? 88  LYS C CE  1 
ATOM   7419 N NZ  . LYS D 2 92  ? -44.679 26.85   36.395  1   79.23  ? 88  LYS C NZ  1 
ATOM   7420 N N   . LYS D 2 93  ? -39.41  26.525  32.031  1   49.63  ? 89  LYS C N   1 
ATOM   7421 C CA  . LYS D 2 93  ? -38.456 27.626  31.915  1   51.38  ? 89  LYS C CA  1 
ATOM   7422 C C   . LYS D 2 93  ? -38.902 28.562  30.806  1   48.64  ? 89  LYS C C   1 
ATOM   7423 O O   . LYS D 2 93  ? -38.728 29.77   30.942  1   48.22  ? 89  LYS C O   1 
ATOM   7424 C CB  . LYS D 2 93  ? -37.01  27.165  31.694  1   54.75  ? 89  LYS C CB  1 
ATOM   7425 C CG  . LYS D 2 93  ? -36.466 26.524  32.948  1   65.27  ? 89  LYS C CG  1 
ATOM   7426 C CD  . LYS D 2 93  ? -34.991 26.137  33.034  1   76.64  ? 89  LYS C CD  1 
ATOM   7427 C CE  . LYS D 2 93  ? -34.752 25.661  34.442  1   83     ? 89  LYS C CE  1 
ATOM   7428 N NZ  . LYS D 2 93  ? -33.381 25.176  34.592  1   100.54 ? 89  LYS C NZ  1 
ATOM   7429 N N   . PHE D 2 94  ? -39.472 27.963  29.746  1   47.07  ? 90  PHE C N   1 
ATOM   7430 C CA  . PHE D 2 94  ? -39.986 28.683  28.599  1   49.99  ? 90  PHE C CA  1 
ATOM   7431 C C   . PHE D 2 94  ? -41.127 29.618  29.017  1   53.51  ? 90  PHE C C   1 
ATOM   7432 O O   . PHE D 2 94  ? -41.095 30.822  28.725  1   56.76  ? 90  PHE C O   1 
ATOM   7433 C CB  . PHE D 2 94  ? -40.407 27.711  27.492  1   49.06  ? 90  PHE C CB  1 
ATOM   7434 C CG  . PHE D 2 94  ? -40.955 28.437  26.269  1   48.86  ? 90  PHE C CG  1 
ATOM   7435 C CD1 . PHE D 2 94  ? -40.151 29.321  25.551  1   49.69  ? 90  PHE C CD1 1 
ATOM   7436 C CD2 . PHE D 2 94  ? -42.285 28.27   25.875  1   47.66  ? 90  PHE C CD2 1 
ATOM   7437 C CE1 . PHE D 2 94  ? -40.664 29.99   24.446  1   50.92  ? 90  PHE C CE1 1 
ATOM   7438 C CE2 . PHE D 2 94  ? -42.788 28.928  24.764  1   48.15  ? 90  PHE C CE2 1 
ATOM   7439 C CZ  . PHE D 2 94  ? -41.981 29.783  24.053  1   49.74  ? 90  PHE C CZ  1 
ATOM   7440 N N   . MET D 2 95  ? -42.133 29.064  29.712  1   53.58  ? 91  MET C N   1 
ATOM   7441 C CA  . MET D 2 95  ? -43.239 29.85   30.253  1   53.78  ? 91  MET C CA  1 
ATOM   7442 C C   . MET D 2 95  ? -42.743 31.03   31.088  1   54.16  ? 91  MET C C   1 
ATOM   7443 O O   . MET D 2 95  ? -43.106 32.176  30.818  1   56.82  ? 91  MET C O   1 
ATOM   7444 C CB  . MET D 2 95  ? -44.208 28.957  31.03   1   52.8   ? 91  MET C CB  1 
ATOM   7445 C CG  . MET D 2 95  ? -45.011 28.073  30.104  1   54.48  ? 91  MET C CG  1 
ATOM   7446 S SD  . MET D 2 95  ? -46.243 26.997  30.87   1   64.86  ? 91  MET C SD  1 
ATOM   7447 C CE  . MET D 2 95  ? -45.349 26.082  32.136  1   54.04  ? 91  MET C CE  1 
ATOM   7448 N N   . ASP D 2 96  ? -41.887 30.754  32.076  1   53.53  ? 92  ASP C N   1 
ATOM   7449 C CA  . ASP D 2 96  ? -41.333 31.79   32.939  1   54.58  ? 92  ASP C CA  1 
ATOM   7450 C C   . ASP D 2 96  ? -40.64  32.881  32.115  1   54.27  ? 92  ASP C C   1 
ATOM   7451 O O   . ASP D 2 96  ? -40.791 34.076  32.399  1   53.73  ? 92  ASP C O   1 
ATOM   7452 C CB  . ASP D 2 96  ? -40.448 31.181  34.017  1   57.16  ? 92  ASP C CB  1 
ATOM   7453 C CG  . ASP D 2 96  ? -41.177 30.37   35.081  1   60.61  ? 92  ASP C CG  1 
ATOM   7454 O OD1 . ASP D 2 96  ? -42.433 30.319  35.025  1   63.29  ? 92  ASP C OD1 1 
ATOM   7455 O OD2 . ASP D 2 96  ? -40.492 29.786  35.959  1   63.48  ? 92  ASP C OD2 1 
ATOM   7456 N N   . ALA D 2 97  ? -39.879 32.468  31.092  1   52.68  ? 93  ALA C N   1 
ATOM   7457 C CA  . ALA D 2 97  ? -39.188 33.407  30.213  1   55.2   ? 93  ALA C CA  1 
ATOM   7458 C C   . ALA D 2 97  ? -40.195 34.239  29.428  1   56.04  ? 93  ALA C C   1 
ATOM   7459 O O   . ALA D 2 97  ? -39.913 35.383  29.077  1   56.26  ? 93  ALA C O   1 
ATOM   7460 C CB  . ALA D 2 97  ? -38.243 32.672  29.267  1   53.25  ? 93  ALA C CB  1 
ATOM   7461 N N   . SER D 2 98  ? -41.348 33.628  29.141  1   58.8   ? 94  SER C N   1 
ATOM   7462 C CA  . SER D 2 98  ? -42.419 34.267  28.392  1   64.27  ? 94  SER C CA  1 
ATOM   7463 C C   . SER D 2 98  ? -43.441 34.945  29.311  1   72.69  ? 94  SER C C   1 
ATOM   7464 O O   . SER D 2 98  ? -44.618 35.018  28.957  1   77.55  ? 94  SER C O   1 
ATOM   7465 C CB  . SER D 2 98  ? -43.115 33.235  27.551  1   60.63  ? 94  SER C CB  1 
ATOM   7466 O OG  . SER D 2 98  ? -42.258 32.739  26.545  1   59.14  ? 94  SER C OG  1 
ATOM   7467 N N   . ALA D 2 99  ? -43.021 35.44   30.484  1   80.24  ? 95  ALA C N   1 
ATOM   7468 C CA  . ALA D 2 99  ? -43.98  35.916  31.474  1   87.3   ? 95  ALA C CA  1 
ATOM   7469 C C   . ALA D 2 99  ? -44.532 37.286  31.078  1   87.28  ? 95  ALA C C   1 
ATOM   7470 O O   . ALA D 2 99  ? -45.726 37.534  31.211  1   86.93  ? 95  ALA C O   1 
ATOM   7471 C CB  . ALA D 2 99  ? -43.358 35.94   32.849  1   92.47  ? 95  ALA C CB  1 
ATOM   7472 N N   . LEU D 2 100 ? -43.655 38.162  30.585  1   84.21  ? 96  LEU C N   1 
ATOM   7473 C CA  . LEU D 2 100 ? -44.072 39.439  30.038  1   86.06  ? 96  LEU C CA  1 
ATOM   7474 C C   . LEU D 2 100 ? -44.691 39.231  28.657  1   91.9   ? 96  LEU C C   1 
ATOM   7475 O O   . LEU D 2 100 ? -45.867 39.521  28.476  1   98.77  ? 96  LEU C O   1 
ATOM   7476 C CB  . LEU D 2 100 ? -42.875 40.38   29.941  1   90.58  ? 96  LEU C CB  1 
ATOM   7477 C CG  . LEU D 2 100 ? -42.077 40.598  31.228  1   92.37  ? 96  LEU C CG  1 
ATOM   7478 C CD1 . LEU D 2 100 ? -41.138 41.819  31.064  1   97.49  ? 96  LEU C CD1 1 
ATOM   7479 C CD2 . LEU D 2 100 ? -43.024 40.74   32.415  1   81.64  ? 96  LEU C CD2 1 
ATOM   7480 N N   . THR D 2 101 ? -43.895 38.723  27.695  1   88.1   ? 97  THR C N   1 
ATOM   7481 C CA  . THR D 2 101 ? -44.228 38.742  26.27   1   80.24  ? 97  THR C CA  1 
ATOM   7482 C C   . THR D 2 101 ? -45.43  37.842  25.942  1   73.94  ? 97  THR C C   1 
ATOM   7483 O O   . THR D 2 101 ? -46.106 38.032  24.946  1   75.82  ? 97  THR C O   1 
ATOM   7484 C CB  . THR D 2 101 ? -43.007 38.434  25.386  1   79.24  ? 97  THR C CB  1 
ATOM   7485 O OG1 . THR D 2 101 ? -42.673 37.046  25.441  1   72.35  ? 97  THR C OG1 1 
ATOM   7486 C CG2 . THR D 2 101 ? -41.795 39.299  25.702  1   80.1   ? 97  THR C CG2 1 
ATOM   7487 N N   . GLY D 2 102 ? -45.723 36.845  26.763  1   69.21  ? 98  GLY C N   1 
ATOM   7488 C CA  . GLY D 2 102 ? -46.728 35.865  26.389  1   65.88  ? 98  GLY C CA  1 
ATOM   7489 C C   . GLY D 2 102 ? -46.184 34.865  25.367  1   64.1   ? 98  GLY C C   1 
ATOM   7490 O O   . GLY D 2 102 ? -45.166 35.109  24.737  1   60.29  ? 98  GLY C O   1 
ATOM   7491 N N   . ILE D 2 103 ? -46.875 33.727  25.243  1   63.44  ? 99  ILE C N   1 
ATOM   7492 C CA  . ILE D 2 103 ? -46.629 32.716  24.229  1   65.69  ? 99  ILE C CA  1 
ATOM   7493 C C   . ILE D 2 103 ? -47.668 32.859  23.105  1   67.61  ? 99  ILE C C   1 
ATOM   7494 O O   . ILE D 2 103 ? -48.879 32.852  23.342  1   69.01  ? 99  ILE C O   1 
ATOM   7495 C CB  . ILE D 2 103 ? -46.737 31.314  24.859  1   62.7   ? 99  ILE C CB  1 
ATOM   7496 C CG1 . ILE D 2 103 ? -45.881 31.163  26.118  1   66.37  ? 99  ILE C CG1 1 
ATOM   7497 C CG2 . ILE D 2 103 ? -46.426 30.248  23.821  1   59.93  ? 99  ILE C CG2 1 
ATOM   7498 C CD1 . ILE D 2 103 ? -45.981 29.805  26.803  1   59.25  ? 99  ILE C CD1 1 
ATOM   7499 N N   . PRO D 2 104 ? -47.255 32.947  21.825  1   64.88  ? 100 PRO C N   1 
ATOM   7500 C CA  . PRO D 2 104 ? -48.232 32.966  20.741  1   64.3   ? 100 PRO C CA  1 
ATOM   7501 C C   . PRO D 2 104 ? -49.124 31.726  20.718  1   61.87  ? 100 PRO C C   1 
ATOM   7502 O O   . PRO D 2 104 ? -48.652 30.601  20.858  1   57.56  ? 100 PRO C O   1 
ATOM   7503 C CB  . PRO D 2 104 ? -47.357 33.146  19.481  1   64.45  ? 100 PRO C CB  1 
ATOM   7504 C CG  . PRO D 2 104 ? -46.087 33.765  20.014  1   64.27  ? 100 PRO C CG  1 
ATOM   7505 C CD  . PRO D 2 104 ? -45.865 33.107  21.371  1   63.52  ? 100 PRO C CD  1 
ATOM   7506 N N   . LEU D 2 105 ? -50.429 31.968  20.55   1   63.7   ? 101 LEU C N   1 
ATOM   7507 C CA  . LEU D 2 105 ? -51.466 30.95   20.435  1   66.53  ? 101 LEU C CA  1 
ATOM   7508 C C   . LEU D 2 105 ? -51.107 29.833  19.437  1   61.69  ? 101 LEU C C   1 
ATOM   7509 O O   . LEU D 2 105 ? -51.336 28.666  19.756  1   62.23  ? 101 LEU C O   1 
ATOM   7510 C CB  . LEU D 2 105 ? -52.817 31.646  20.166  1   74     ? 101 LEU C CB  1 
ATOM   7511 C CG  . LEU D 2 105 ? -54.067 30.785  19.882  1   80.45  ? 101 LEU C CG  1 
ATOM   7512 C CD1 . LEU D 2 105 ? -54.169 30.23   18.446  1   83.39  ? 101 LEU C CD1 1 
ATOM   7513 C CD2 . LEU D 2 105 ? -54.317 29.645  20.876  1   75.1   ? 101 LEU C CD2 1 
ATOM   7514 N N   . PRO D 2 106 ? -50.615 30.09   18.196  1   59.96  ? 102 PRO C N   1 
ATOM   7515 C CA  . PRO D 2 106 ? -50.209 29.001  17.309  1   59.46  ? 102 PRO C CA  1 
ATOM   7516 C C   . PRO D 2 106 ? -49.143 28.081  17.898  1   57.01  ? 102 PRO C C   1 
ATOM   7517 O O   . PRO D 2 106 ? -49.202 26.872  17.68   1   56.58  ? 102 PRO C O   1 
ATOM   7518 C CB  . PRO D 2 106 ? -49.758 29.693  15.989  1   59.9   ? 102 PRO C CB  1 
ATOM   7519 C CG  . PRO D 2 106 ? -50.459 31.03   16.02   1   60.73  ? 102 PRO C CG  1 
ATOM   7520 C CD  . PRO D 2 106 ? -50.516 31.391  17.508  1   62.16  ? 102 PRO C CD  1 
ATOM   7521 N N   . LEU D 2 107 ? -48.182 28.648  18.645  1   55.98  ? 103 LEU C N   1 
ATOM   7522 C CA  . LEU D 2 107 ? -47.175 27.832  19.316  1   54.37  ? 103 LEU C CA  1 
ATOM   7523 C C   . LEU D 2 107 ? -47.829 26.966  20.389  1   52.13  ? 103 LEU C C   1 
ATOM   7524 O O   . LEU D 2 107 ? -47.554 25.773  20.472  1   51.73  ? 103 LEU C O   1 
ATOM   7525 C CB  . LEU D 2 107 ? -46.035 28.674  19.894  1   55.69  ? 103 LEU C CB  1 
ATOM   7526 C CG  . LEU D 2 107 ? -44.759 27.903  20.266  1   54.81  ? 103 LEU C CG  1 
ATOM   7527 C CD1 . LEU D 2 107 ? -44.055 27.309  19.076  1   53.11  ? 103 LEU C CD1 1 
ATOM   7528 C CD2 . LEU D 2 107 ? -43.799 28.814  21.012  1   55.18  ? 103 LEU C CD2 1 
ATOM   7529 N N   . ILE D 2 108 ? -48.724 27.569  21.189  1   52.91  ? 104 ILE C N   1 
ATOM   7530 C CA  . ILE D 2 108 ? -49.445 26.816  22.21   1   52.63  ? 104 ILE C CA  1 
ATOM   7531 C C   . ILE D 2 108 ? -50.155 25.621  21.564  1   53.36  ? 104 ILE C C   1 
ATOM   7532 O O   . ILE D 2 108 ? -50.041 24.473  22.005  1   52.71  ? 104 ILE C O   1 
ATOM   7533 C CB  . ILE D 2 108 ? -50.411 27.721  23.009  1   51.24  ? 104 ILE C CB  1 
ATOM   7534 C CG1 . ILE D 2 108 ? -49.655 28.78   23.786  1   51.06  ? 104 ILE C CG1 1 
ATOM   7535 C CG2 . ILE D 2 108 ? -51.314 26.888  23.924  1   48.5   ? 104 ILE C CG2 1 
ATOM   7536 C CD1 . ILE D 2 108 ? -50.535 29.86   24.391  1   52.79  ? 104 ILE C CD1 1 
ATOM   7537 N N   . LYS D 2 109 ? -50.908 25.911  20.507  1   54.71  ? 105 LYS C N   1 
ATOM   7538 C CA  . LYS D 2 109 ? -51.712 24.895  19.85   1   55.94  ? 105 LYS C CA  1 
ATOM   7539 C C   . LYS D 2 109 ? -50.81  23.806  19.279  1   52.86  ? 105 LYS C C   1 
ATOM   7540 O O   . LYS D 2 109 ? -51.144 22.626  19.34   1   52.77  ? 105 LYS C O   1 
ATOM   7541 C CB  . LYS D 2 109 ? -52.56  25.572  18.764  1   56.75  ? 105 LYS C CB  1 
ATOM   7542 C CG  . LYS D 2 109 ? -53.243 24.631  17.792  1   57.84  ? 105 LYS C CG  1 
ATOM   7543 C CD  . LYS D 2 109 ? -54.089 25.422  16.797  1   60.44  ? 105 LYS C CD  1 
ATOM   7544 C CE  . LYS D 2 109 ? -55.131 26.323  17.417  1   60.44  ? 105 LYS C CE  1 
ATOM   7545 N NZ  . LYS D 2 109 ? -55.82  27.073  16.357  1   64.11  ? 105 LYS C NZ  1 
ATOM   7546 N N   . SER D 2 110 ? -49.692 24.222  18.676  1   52.9   ? 106 SER C N   1 
ATOM   7547 C CA  . SER D 2 110 ? -48.71  23.29   18.14   1   52.44  ? 106 SER C CA  1 
ATOM   7548 C C   . SER D 2 110 ? -48.197 22.363  19.245  1   51.72  ? 106 SER C C   1 
ATOM   7549 O O   . SER D 2 110 ? -48.142 21.145  19.051  1   52.57  ? 106 SER C O   1 
ATOM   7550 C CB  . SER D 2 110 ? -47.574 24.04   17.512  1   52.51  ? 106 SER C CB  1 
ATOM   7551 O OG  . SER D 2 110 ? -46.477 23.166  17.278  1   52.99  ? 106 SER C OG  1 
ATOM   7552 N N   . TYR D 2 111 ? -47.807 22.953  20.39   1   48.61  ? 107 TYR C N   1 
ATOM   7553 C CA  . TYR D 2 111 ? -47.218 22.189  21.473  1   48.24  ? 107 TYR C CA  1 
ATOM   7554 C C   . TYR D 2 111 ? -48.23  21.196  22.044  1   49.94  ? 107 TYR C C   1 
ATOM   7555 O O   . TYR D 2 111 ? -47.888 20.047  22.303  1   53.83  ? 107 TYR C O   1 
ATOM   7556 C CB  . TYR D 2 111 ? -46.689 23.093  22.581  1   45.61  ? 107 TYR C CB  1 
ATOM   7557 C CG  . TYR D 2 111 ? -45.361 23.784  22.357  1   45.87  ? 107 TYR C CG  1 
ATOM   7558 C CD1 . TYR D 2 111 ? -44.487 23.428  21.325  1   46.52  ? 107 TYR C CD1 1 
ATOM   7559 C CD2 . TYR D 2 111 ? -44.953 24.774  23.24   1   47.01  ? 107 TYR C CD2 1 
ATOM   7560 C CE1 . TYR D 2 111 ? -43.243 24.041  21.184  1   46.51  ? 107 TYR C CE1 1 
ATOM   7561 C CE2 . TYR D 2 111 ? -43.724 25.398  23.103  1   48.62  ? 107 TYR C CE2 1 
ATOM   7562 C CZ  . TYR D 2 111 ? -42.864 25.032  22.078  1   48.22  ? 107 TYR C CZ  1 
ATOM   7563 O OH  . TYR D 2 111 ? -41.684 25.724  21.975  1   50.54  ? 107 TYR C OH  1 
ATOM   7564 N N   . LEU D 2 112 ? -49.475 21.631  22.258  1   51.91  ? 108 LEU C N   1 
ATOM   7565 C CA  . LEU D 2 112 ? -50.491 20.741  22.79   1   49.46  ? 108 LEU C CA  1 
ATOM   7566 C C   . LEU D 2 112 ? -50.686 19.58   21.822  1   49.62  ? 108 LEU C C   1 
ATOM   7567 O O   . LEU D 2 112 ? -50.888 18.44   22.244  1   49.73  ? 108 LEU C O   1 
ATOM   7568 C CB  . LEU D 2 112 ? -51.805 21.481  23.029  1   48.39  ? 108 LEU C CB  1 
ATOM   7569 C CG  . LEU D 2 112 ? -52.92  20.607  23.624  1   47.8   ? 108 LEU C CG  1 
ATOM   7570 C CD1 . LEU D 2 112 ? -52.575 20.132  25.008  1   44.71  ? 108 LEU C CD1 1 
ATOM   7571 C CD2 . LEU D 2 112 ? -54.249 21.359  23.676  1   50.2   ? 108 LEU C CD2 1 
ATOM   7572 N N   . PHE D 2 113 ? -50.665 19.885  20.518  1   51.37  ? 109 PHE C N   1 
ATOM   7573 C CA  . PHE D 2 113 ? -50.913 18.873  19.499  1   52.42  ? 109 PHE C CA  1 
ATOM   7574 C C   . PHE D 2 113 ? -49.811 17.82   19.586  1   51.4   ? 109 PHE C C   1 
ATOM   7575 O O   . PHE D 2 113 ? -50.082 16.614  19.558  1   51.8   ? 109 PHE C O   1 
ATOM   7576 C CB  . PHE D 2 113 ? -51.001 19.556  18.128  1   53.98  ? 109 PHE C CB  1 
ATOM   7577 C CG  . PHE D 2 113 ? -51.328 18.636  16.966  1   53.72  ? 109 PHE C CG  1 
ATOM   7578 C CD1 . PHE D 2 113 ? -52.585 18.045  16.871  1   54.8   ? 109 PHE C CD1 1 
ATOM   7579 C CD2 . PHE D 2 113 ? -50.379 18.377  15.975  1   55.41  ? 109 PHE C CD2 1 
ATOM   7580 C CE1 . PHE D 2 113 ? -52.893 17.196  15.815  1   60.04  ? 109 PHE C CE1 1 
ATOM   7581 C CE2 . PHE D 2 113 ? -50.684 17.526  14.911  1   60.69  ? 109 PHE C CE2 1 
ATOM   7582 C CZ  . PHE D 2 113 ? -51.941 16.929  14.833  1   62.29  ? 109 PHE C CZ  1 
ATOM   7583 N N   . GLN D 2 114 ? -48.569 18.292  19.761  1   50.16  ? 110 GLN C N   1 
ATOM   7584 C CA  . GLN D 2 114 ? -47.42  17.397  19.832  1   50.58  ? 110 GLN C CA  1 
ATOM   7585 C C   . GLN D 2 114 ? -47.443 16.568  21.119  1   48.07  ? 110 GLN C C   1 
ATOM   7586 O O   . GLN D 2 114 ? -47.128 15.369  21.101  1   47.32  ? 110 GLN C O   1 
ATOM   7587 C CB  . GLN D 2 114 ? -46.129 18.194  19.68   1   50.8   ? 110 GLN C CB  1 
ATOM   7588 C CG  . GLN D 2 114 ? -45.921 18.82   18.308  1   50.11  ? 110 GLN C CG  1 
ATOM   7589 C CD  . GLN D 2 114 ? -44.563 19.479  18.262  1   53.83  ? 110 GLN C CD  1 
ATOM   7590 O OE1 . GLN D 2 114 ? -43.532 18.792  18.383  1   57.64  ? 110 GLN C OE1 1 
ATOM   7591 N NE2 . GLN D 2 114 ? -44.55  20.806  18.175  1   48.56  ? 110 GLN C NE2 1 
ATOM   7592 N N   . LEU D 2 115 ? -47.832 17.22   22.225  1   46.92  ? 111 LEU C N   1 
ATOM   7593 C CA  . LEU D 2 115 ? -47.884 16.567  23.528  1   47.89  ? 111 LEU C CA  1 
ATOM   7594 C C   . LEU D 2 115 ? -48.859 15.39   23.469  1   47.19  ? 111 LEU C C   1 
ATOM   7595 O O   . LEU D 2 115 ? -48.573 14.319  24.011  1   46.07  ? 111 LEU C O   1 
ATOM   7596 C CB  . LEU D 2 115 ? -48.224 17.56   24.637  1   45.14  ? 111 LEU C CB  1 
ATOM   7597 C CG  . LEU D 2 115 ? -47.129 18.558  24.98   1   44.78  ? 111 LEU C CG  1 
ATOM   7598 C CD1 . LEU D 2 115 ? -47.635 19.611  25.944  1   43.71  ? 111 LEU C CD1 1 
ATOM   7599 C CD2 . LEU D 2 115 ? -45.991 17.787  25.594  1   44.18  ? 111 LEU C CD2 1 
ATOM   7600 N N   . LEU D 2 116 ? -49.977 15.617  22.769  1   47.07  ? 112 LEU C N   1 
ATOM   7601 C CA  . LEU D 2 116 ? -51.032 14.638  22.583  1   50.59  ? 112 LEU C CA  1 
ATOM   7602 C C   . LEU D 2 116 ? -50.569 13.509  21.67   1   52.4   ? 112 LEU C C   1 
ATOM   7603 O O   . LEU D 2 116 ? -50.964 12.362  21.872  1   54.56  ? 112 LEU C O   1 
ATOM   7604 C CB  . LEU D 2 116 ? -52.262 15.329  21.993  1   50.33  ? 112 LEU C CB  1 
ATOM   7605 C CG  . LEU D 2 116 ? -53.033 16.229  22.962  1   48.48  ? 112 LEU C CG  1 
ATOM   7606 C CD1 . LEU D 2 116 ? -53.897 17.155  22.145  1   51.25  ? 112 LEU C CD1 1 
ATOM   7607 C CD2 . LEU D 2 116 ? -53.862 15.414  23.94   1   46.2   ? 112 LEU C CD2 1 
ATOM   7608 N N   . GLN D 2 117 ? -49.765 13.841  20.649  1   52.49  ? 113 GLN C N   1 
ATOM   7609 C CA  . GLN D 2 117 ? -49.241 12.799  19.784  1   51.01  ? 113 GLN C CA  1 
ATOM   7610 C C   . GLN D 2 117 ? -48.3   11.896  20.583  1   51.44  ? 113 GLN C C   1 
ATOM   7611 O O   . GLN D 2 117 ? -48.358 10.669  20.45   1   51.74  ? 113 GLN C O   1 
ATOM   7612 C CB  . GLN D 2 117 ? -48.532 13.428  18.595  1   51.78  ? 113 GLN C CB  1 
ATOM   7613 C CG  . GLN D 2 117 ? -49.473 13.888  17.494  1   57.02  ? 113 GLN C CG  1 
ATOM   7614 C CD  . GLN D 2 117 ? -48.676 14.371  16.301  1   66.94  ? 113 GLN C CD  1 
ATOM   7615 O OE1 . GLN D 2 117 ? -48.41  13.608  15.372  1   75.48  ? 113 GLN C OE1 1 
ATOM   7616 N NE2 . GLN D 2 117 ? -48.216 15.616  16.317  1   69.39  ? 113 GLN C NE2 1 
ATOM   7617 N N   . GLY D 2 118 ? -47.424 12.51   21.406  1   49.56  ? 114 GLY C N   1 
ATOM   7618 C CA  . GLY D 2 118 ? -46.515 11.736  22.235  1   46.44  ? 114 GLY C CA  1 
ATOM   7619 C C   . GLY D 2 118 ? -47.28  10.838  23.204  1   45.5   ? 114 GLY C C   1 
ATOM   7620 O O   . GLY D 2 118 ? -46.958 9.656   23.386  1   43.97  ? 114 GLY C O   1 
ATOM   7621 N N   . LEU D 2 119 ? -48.323 11.418  23.807  1   47.25  ? 115 LEU C N   1 
ATOM   7622 C CA  . LEU D 2 119 ? -49.054 10.735  24.861  1   48     ? 115 LEU C CA  1 
ATOM   7623 C C   . LEU D 2 119 ? -49.886 9.572   24.304  1   48.19  ? 115 LEU C C   1 
ATOM   7624 O O   . LEU D 2 119 ? -49.997 8.515   24.95   1   48.46  ? 115 LEU C O   1 
ATOM   7625 C CB  . LEU D 2 119 ? -49.898 11.74   25.639  1   47.22  ? 115 LEU C CB  1 
ATOM   7626 C CG  . LEU D 2 119 ? -50.629 11.157  26.854  1   47.45  ? 115 LEU C CG  1 
ATOM   7627 C CD1 . LEU D 2 119 ? -49.663 10.609  27.895  1   45.26  ? 115 LEU C CD1 1 
ATOM   7628 C CD2 . LEU D 2 119 ? -51.56  12.209  27.436  1   47.94  ? 115 LEU C CD2 1 
ATOM   7629 N N   . ALA D 2 120 ? -50.49  9.782   23.126  1   47.2   ? 116 ALA C N   1 
ATOM   7630 C CA  . ALA D 2 120 ? -51.275 8.747   22.468  1   47.65  ? 116 ALA C CA  1 
ATOM   7631 C C   . ALA D 2 120 ? -50.394 7.531   22.178  1   48.67  ? 116 ALA C C   1 
ATOM   7632 O O   . ALA D 2 120 ? -50.817 6.389   22.373  1   50.22  ? 116 ALA C O   1 
ATOM   7633 C CB  . ALA D 2 120 ? -51.91  9.302   21.21   1   45.94  ? 116 ALA C CB  1 
ATOM   7634 N N   . PHE D 2 121 ? -49.167 7.796   21.696  1   48.75  ? 117 PHE C N   1 
ATOM   7635 C CA  . PHE D 2 121 ? -48.138 6.784   21.517  1   46.95  ? 117 PHE C CA  1 
ATOM   7636 C C   . PHE D 2 121 ? -47.87  6.041   22.823  1   45.11  ? 117 PHE C C   1 
ATOM   7637 O O   . PHE D 2 121 ? -47.74  4.829   22.792  1   48.64  ? 117 PHE C O   1 
ATOM   7638 C CB  . PHE D 2 121 ? -46.86  7.389   20.915  1   49.65  ? 117 PHE C CB  1 
ATOM   7639 C CG  . PHE D 2 121 ? -45.958 6.366   20.241  1   49.72  ? 117 PHE C CG  1 
ATOM   7640 C CD1 . PHE D 2 121 ? -45.078 5.577   20.989  1   50.67  ? 117 PHE C CD1 1 
ATOM   7641 C CD2 . PHE D 2 121 ? -46.017 6.162   18.862  1   48.72  ? 117 PHE C CD2 1 
ATOM   7642 C CE1 . PHE D 2 121 ? -44.276 4.616   20.364  1   49.1   ? 117 PHE C CE1 1 
ATOM   7643 C CE2 . PHE D 2 121 ? -45.211 5.206   18.244  1   49.8   ? 117 PHE C CE2 1 
ATOM   7644 C CZ  . PHE D 2 121 ? -44.338 4.436   18.992  1   48.36  ? 117 PHE C CZ  1 
ATOM   7645 N N   . CYS D 2 122 ? -47.712 6.747   23.952  1   44.29  ? 118 CYS C N   1 
ATOM   7646 C CA  . CYS D 2 122 ? -47.493 6.085   25.239  1   43.17  ? 118 CYS C CA  1 
ATOM   7647 C C   . CYS D 2 122 ? -48.638 5.129   25.558  1   44.78  ? 118 CYS C C   1 
ATOM   7648 O O   . CYS D 2 122 ? -48.408 3.971   25.9    1   46.26  ? 118 CYS C O   1 
ATOM   7649 C CB  . CYS D 2 122 ? -47.346 7.062   26.398  1   41.95  ? 118 CYS C CB  1 
ATOM   7650 S SG  . CYS D 2 122 ? -45.793 7.987   26.303  1   45.66  ? 118 CYS C SG  1 
ATOM   7651 N N   . HIS D 2 123 ? -49.879 5.638   25.459  1   46.03  ? 119 HIS C N   1 
ATOM   7652 C CA  . HIS D 2 123 ? -51.067 4.893   25.841  1   45.91  ? 119 HIS C CA  1 
ATOM   7653 C C   . HIS D 2 123 ? -51.268 3.726   24.873  1   47.01  ? 119 HIS C C   1 
ATOM   7654 O O   . HIS D 2 123 ? -51.624 2.638   25.31   1   49.86  ? 119 HIS C O   1 
ATOM   7655 C CB  . HIS D 2 123 ? -52.269 5.839   26.004  1   47.69  ? 119 HIS C CB  1 
ATOM   7656 C CG  . HIS D 2 123 ? -52.121 6.841   27.115  1   48.3   ? 119 HIS C CG  1 
ATOM   7657 N ND1 . HIS D 2 123 ? -52.842 8.022   27.158  1   48.07  ? 119 HIS C ND1 1 
ATOM   7658 C CD2 . HIS D 2 123 ? -51.338 6.84    28.233  1   47.32  ? 119 HIS C CD2 1 
ATOM   7659 C CE1 . HIS D 2 123 ? -52.499 8.702   28.254  1   47.9   ? 119 HIS C CE1 1 
ATOM   7660 N NE2 . HIS D 2 123 ? -51.589 8.002   28.923  1   46.95  ? 119 HIS C NE2 1 
ATOM   7661 N N   . SER D 2 124 ? -51.059 3.954   23.566  1   46.43  ? 120 SER C N   1 
ATOM   7662 C CA  . SER D 2 124 ? -51.061 2.895   22.56   1   47.85  ? 120 SER C CA  1 
ATOM   7663 C C   . SER D 2 124 ? -50.045 1.798   22.855  1   47.56  ? 120 SER C C   1 
ATOM   7664 O O   . SER D 2 124 ? -50.144 0.737   22.251  1   47.27  ? 120 SER C O   1 
ATOM   7665 C CB  . SER D 2 124 ? -50.763 3.418   21.192  1   50.04  ? 120 SER C CB  1 
ATOM   7666 O OG  . SER D 2 124 ? -51.784 4.289   20.734  1   57.87  ? 120 SER C OG  1 
ATOM   7667 N N   . HIS D 2 125 ? -49.025 2.075   23.695  1   48.87  ? 121 HIS C N   1 
ATOM   7668 C CA  . HIS D 2 125 ? -47.963 1.113   23.986  1   49.62  ? 121 HIS C CA  1 
ATOM   7669 C C   . HIS D 2 125 ? -47.993 0.722   25.461  1   49.23  ? 121 HIS C C   1 
ATOM   7670 O O   . HIS D 2 125 ? -46.985 0.301   26.017  1   48.9   ? 121 HIS C O   1 
ATOM   7671 C CB  . HIS D 2 125 ? -46.612 1.624   23.472  1   49.97  ? 121 HIS C CB  1 
ATOM   7672 C CG  . HIS D 2 125 ? -46.559 1.828   21.989  1   52.99  ? 121 HIS C CG  1 
ATOM   7673 N ND1 . HIS D 2 125 ? -47.208 2.869   21.349  1   56.16  ? 121 HIS C ND1 1 
ATOM   7674 C CD2 . HIS D 2 125 ? -45.97  1.109   21.005  1   54.03  ? 121 HIS C CD2 1 
ATOM   7675 C CE1 . HIS D 2 125 ? -46.995 2.791   20.025  1   55.46  ? 121 HIS C CE1 1 
ATOM   7676 N NE2 . HIS D 2 125 ? -46.23  1.741   19.802  1   54.85  ? 121 HIS C NE2 1 
ATOM   7677 N N   . ARG D 2 126 ? -49.17  0.911   26.079  1   50.21  ? 122 ARG C N   1 
ATOM   7678 C CA  . ARG D 2 126 ? -49.531 0.487   27.432  1   47.74  ? 122 ARG C CA  1 
ATOM   7679 C C   . ARG D 2 126 ? -48.61  1.109   28.492  1   45.8   ? 122 ARG C C   1 
ATOM   7680 O O   . ARG D 2 126 ? -48.279 0.462   29.482  1   47.32  ? 122 ARG C O   1 
ATOM   7681 C CB  . ARG D 2 126 ? -49.696 -1.035  27.521  1   46.44  ? 122 ARG C CB  1 
ATOM   7682 C CG  . ARG D 2 126 ? -48.504 -1.834  27.012  1   46.55  ? 122 ARG C CG  1 
ATOM   7683 C CD  . ARG D 2 126 ? -47.462 -2.16   28.082  1   47.3   ? 122 ARG C CD  1 
ATOM   7684 N NE  . ARG D 2 126 ? -46.385 -3.092  27.709  1   49.24  ? 122 ARG C NE  1 
ATOM   7685 C CZ  . ARG D 2 126 ? -45.244 -2.785  27.026  1   47.93  ? 122 ARG C CZ  1 
ATOM   7686 N NH1 . ARG D 2 126 ? -45.017 -1.567  26.54   1   45.76  ? 122 ARG C NH1 1 
ATOM   7687 N NH2 . ARG D 2 126 ? -44.353 -3.729  26.785  1   47.01  ? 122 ARG C NH2 1 
ATOM   7688 N N   . VAL D 2 127 ? -48.285 2.4     28.354  1   43.65  ? 123 VAL C N   1 
ATOM   7689 C CA  . VAL D 2 127 ? -47.452 3.089   29.339  1   43.31  ? 123 VAL C CA  1 
ATOM   7690 C C   . VAL D 2 127 ? -48.196 4.316   29.843  1   43.32  ? 123 VAL C C   1 
ATOM   7691 O O   . VAL D 2 127 ? -48.581 5.173   29.06   1   43.77  ? 123 VAL C O   1 
ATOM   7692 C CB  . VAL D 2 127 ? -46.084 3.51    28.751  1   42.96  ? 123 VAL C CB  1 
ATOM   7693 C CG1 . VAL D 2 127 ? -45.418 4.643   29.544  1   40.43  ? 123 VAL C CG1 1 
ATOM   7694 C CG2 . VAL D 2 127 ? -45.163 2.304   28.49   1   40.9   ? 123 VAL C CG2 1 
ATOM   7695 N N   . LEU D 2 128 ? -48.394 4.38    31.16   1   44.06  ? 124 LEU C N   1 
ATOM   7696 C CA  . LEU D 2 128 ? -48.781 5.62    31.826  1   44.84  ? 124 LEU C CA  1 
ATOM   7697 C C   . LEU D 2 128 ? -47.506 6.418   32.143  1   44.16  ? 124 LEU C C   1 
ATOM   7698 O O   . LEU D 2 128 ? -46.526 5.836   32.614  1   43.64  ? 124 LEU C O   1 
ATOM   7699 C CB  . LEU D 2 128 ? -49.533 5.292   33.117  1   43.74  ? 124 LEU C CB  1 
ATOM   7700 C CG  . LEU D 2 128 ? -50.796 4.443   32.963  1   46.14  ? 124 LEU C CG  1 
ATOM   7701 C CD1 . LEU D 2 128 ? -51.318 4.061   34.34   1   46.29  ? 124 LEU C CD1 1 
ATOM   7702 C CD2 . LEU D 2 128 ? -51.847 5.205   32.154  1   44.85  ? 124 LEU C CD2 1 
ATOM   7703 N N   . HIS D 2 129 ? -47.546 7.745   31.937  1   43.32  ? 125 HIS C N   1 
ATOM   7704 C CA  . HIS D 2 129 ? -46.451 8.629   32.294  1   43.04  ? 125 HIS C CA  1 
ATOM   7705 C C   . HIS D 2 129 ? -46.501 8.956   33.783  1   44.86  ? 125 HIS C C   1 
ATOM   7706 O O   . HIS D 2 129 ? -45.522 8.738   34.488  1   46.52  ? 125 HIS C O   1 
ATOM   7707 C CB  . HIS D 2 129 ? -46.463 9.908   31.463  1   42.01  ? 125 HIS C CB  1 
ATOM   7708 C CG  . HIS D 2 129 ? -45.218 10.709  31.624  1   43.7   ? 125 HIS C CG  1 
ATOM   7709 N ND1 . HIS D 2 129 ? -44.981 11.556  32.692  1   43.19  ? 125 HIS C ND1 1 
ATOM   7710 C CD2 . HIS D 2 129 ? -44.13  10.803  30.794  1   42.16  ? 125 HIS C CD2 1 
ATOM   7711 C CE1 . HIS D 2 129 ? -43.802 12.14   32.507  1   43.23  ? 125 HIS C CE1 1 
ATOM   7712 N NE2 . HIS D 2 129 ? -43.273 11.7    31.359  1   41.32  ? 125 HIS C NE2 1 
ATOM   7713 N N   . ARG D 2 130 ? -47.63  9.506   34.239  1   45.12  ? 126 ARG C N   1 
ATOM   7714 C CA  . ARG D 2 130 ? -47.91  9.741   35.648  1   44.94  ? 126 ARG C CA  1 
ATOM   7715 C C   . ARG D 2 130 ? -47.057 10.866  36.264  1   46.82  ? 126 ARG C C   1 
ATOM   7716 O O   . ARG D 2 130 ? -47.036 11.022  37.49   1   46     ? 126 ARG C O   1 
ATOM   7717 C CB  . ARG D 2 130 ? -47.732 8.451   36.45   1   43.88  ? 126 ARG C CB  1 
ATOM   7718 C CG  . ARG D 2 130 ? -48.499 7.25    35.928  1   43.37  ? 126 ARG C CG  1 
ATOM   7719 C CD  . ARG D 2 130 ? -48.607 6.2     37.009  1   44.36  ? 126 ARG C CD  1 
ATOM   7720 N NE  . ARG D 2 130 ? -47.294 5.699   37.417  1   44.04  ? 126 ARG C NE  1 
ATOM   7721 C CZ  . ARG D 2 130 ? -47.065 4.681   38.247  1   43.9   ? 126 ARG C CZ  1 
ATOM   7722 N NH1 . ARG D 2 130 ? -48.065 4.104   38.885  1   43.51  ? 126 ARG C NH1 1 
ATOM   7723 N NH2 . ARG D 2 130 ? -45.822 4.261   38.445  1   42.2   ? 126 ARG C NH2 1 
ATOM   7724 N N   . ASP D 2 131 ? -46.402 11.703  35.442  1   45.25  ? 127 ASP C N   1 
ATOM   7725 C CA  . ASP D 2 131 ? -45.716 12.85   36.012  1   46.4   ? 127 ASP C CA  1 
ATOM   7726 C C   . ASP D 2 131 ? -45.625 13.957  34.963  1   47.78  ? 127 ASP C C   1 
ATOM   7727 O O   . ASP D 2 131 ? -44.588 14.598  34.803  1   48.4   ? 127 ASP C O   1 
ATOM   7728 C CB  . ASP D 2 131 ? -44.38  12.466  36.636  1   45.77  ? 127 ASP C CB  1 
ATOM   7729 C CG  . ASP D 2 131 ? -43.745 13.492  37.571  1   49.6   ? 127 ASP C CG  1 
ATOM   7730 O OD1 . ASP D 2 131 ? -44.514 14.301  38.195  1   49.06  ? 127 ASP C OD1 1 
ATOM   7731 O OD2 . ASP D 2 131 ? -42.469 13.511  37.629  1   53.39  ? 127 ASP C OD2 1 
ATOM   7732 N N   . LEU D 2 132 ? -46.732 14.204  34.266  1   47.18  ? 128 LEU C N   1 
ATOM   7733 C CA  . LEU D 2 132 ? -46.774 15.267  33.281  1   47.37  ? 128 LEU C CA  1 
ATOM   7734 C C   . LEU D 2 132 ? -46.864 16.597  34.011  1   49.75  ? 128 LEU C C   1 
ATOM   7735 O O   . LEU D 2 132 ? -47.781 16.844  34.785  1   55.88  ? 128 LEU C O   1 
ATOM   7736 C CB  . LEU D 2 132 ? -47.92  15.025  32.298  1   45.43  ? 128 LEU C CB  1 
ATOM   7737 C CG  . LEU D 2 132 ? -47.766 13.789  31.395  1   45.26  ? 128 LEU C CG  1 
ATOM   7738 C CD1 . LEU D 2 132 ? -49.029 13.582  30.576  1   43.67  ? 128 LEU C CD1 1 
ATOM   7739 C CD2 . LEU D 2 132 ? -46.53  13.826  30.458  1   40.94  ? 128 LEU C CD2 1 
ATOM   7740 N N   . LYS D 2 133 ? -45.833 17.406  33.819  1   48.11  ? 129 LYS C N   1 
ATOM   7741 C CA  . LYS D 2 133 ? -45.774 18.766  34.316  1   48.91  ? 129 LYS C CA  1 
ATOM   7742 C C   . LYS D 2 133 ? -44.782 19.545  33.452  1   48.32  ? 129 LYS C C   1 
ATOM   7743 O O   . LYS D 2 133 ? -43.947 18.955  32.773  1   48.8   ? 129 LYS C O   1 
ATOM   7744 C CB  . LYS D 2 133 ? -45.416 18.779  35.8    1   48     ? 129 LYS C CB  1 
ATOM   7745 C CG  . LYS D 2 133 ? -44.231 17.894  36.131  1   48.66  ? 129 LYS C CG  1 
ATOM   7746 C CD  . LYS D 2 133 ? -43.857 18.066  37.598  1   48.22  ? 129 LYS C CD  1 
ATOM   7747 C CE  . LYS D 2 133 ? -42.514 17.458  37.883  1   49.96  ? 129 LYS C CE  1 
ATOM   7748 N NZ  . LYS D 2 133 ? -42.095 17.709  39.255  1   51.52  ? 129 LYS C NZ  1 
ATOM   7749 N N   . PRO D 2 134 ? -44.856 20.89   33.402  1   47.97  ? 130 PRO C N   1 
ATOM   7750 C CA  . PRO D 2 134 ? -44.04  21.642  32.449  1   46.84  ? 130 PRO C CA  1 
ATOM   7751 C C   . PRO D 2 134 ? -42.558 21.29   32.549  1   45.95  ? 130 PRO C C   1 
ATOM   7752 O O   . PRO D 2 134 ? -41.84  21.299  31.542  1   45.1   ? 130 PRO C O   1 
ATOM   7753 C CB  . PRO D 2 134 ? -44.311 23.1    32.824  1   47.77  ? 130 PRO C CB  1 
ATOM   7754 C CG  . PRO D 2 134 ? -45.66  23.063  33.53   1   48.75  ? 130 PRO C CG  1 
ATOM   7755 C CD  . PRO D 2 134 ? -45.718 21.731  34.248  1   47.91  ? 130 PRO C CD  1 
ATOM   7756 N N   . GLN D 2 135 ? -42.107 21.005  33.779  1   46.57  ? 131 GLN C N   1 
ATOM   7757 C CA  . GLN D 2 135 ? -40.697 20.717  34.053  1   46.65  ? 131 GLN C CA  1 
ATOM   7758 C C   . GLN D 2 135 ? -40.251 19.442  33.338  1   45.55  ? 131 GLN C C   1 
ATOM   7759 O O   . GLN D 2 135 ? -39.067 19.304  33.127  1   48.28  ? 131 GLN C O   1 
ATOM   7760 C CB  . GLN D 2 135 ? -40.36  20.562  35.533  1   46.12  ? 131 GLN C CB  1 
ATOM   7761 C CG  . GLN D 2 135 ? -40.725 21.774  36.396  1   52.12  ? 131 GLN C CG  1 
ATOM   7762 C CD  . GLN D 2 135 ? -42.207 21.999  36.693  1   56.91  ? 131 GLN C CD  1 
ATOM   7763 O OE1 . GLN D 2 135 ? -43.131 21.353  36.157  1   56.5   ? 131 GLN C OE1 1 
ATOM   7764 N NE2 . GLN D 2 135 ? -42.451 23.003  37.526  1   56.03  ? 131 GLN C NE2 1 
ATOM   7765 N N   . ASN D 2 136 ? -41.174 18.527  32.979  1   43.79  ? 132 ASN C N   1 
ATOM   7766 C CA  . ASN D 2 136 ? -40.882 17.247  32.333  1   42.29  ? 132 ASN C CA  1 
ATOM   7767 C C   . ASN D 2 136 ? -41.128 17.279  30.818  1   42.07  ? 132 ASN C C   1 
ATOM   7768 O O   . ASN D 2 136 ? -41.104 16.25   30.159  1   44.07  ? 132 ASN C O   1 
ATOM   7769 C CB  . ASN D 2 136 ? -41.625 16.092  33.005  1   41.88  ? 132 ASN C CB  1 
ATOM   7770 C CG  . ASN D 2 136 ? -41.116 15.847  34.421  1   45.56  ? 132 ASN C CG  1 
ATOM   7771 O OD1 . ASN D 2 136 ? -40.057 16.369  34.816  1   47.58  ? 132 ASN C OD1 1 
ATOM   7772 N ND2 . ASN D 2 136 ? -41.852 15.091  35.229  1   42.21  ? 132 ASN C ND2 1 
ATOM   7773 N N   . LEU D 2 137 ? -41.39  18.454  30.255  1   41.41  ? 133 LEU C N   1 
ATOM   7774 C CA  . LEU D 2 137 ? -41.645 18.6    28.84   1   41.34  ? 133 LEU C CA  1 
ATOM   7775 C C   . LEU D 2 137 ? -40.525 19.462  28.266  1   42.94  ? 133 LEU C C   1 
ATOM   7776 O O   . LEU D 2 137 ? -40.247 20.557  28.781  1   43.03  ? 133 LEU C O   1 
ATOM   7777 C CB  . LEU D 2 137 ? -43.026 19.22   28.62   1   41.42  ? 133 LEU C CB  1 
ATOM   7778 C CG  . LEU D 2 137 ? -44.196 18.524  29.331  1   42.71  ? 133 LEU C CG  1 
ATOM   7779 C CD1 . LEU D 2 137 ? -45.508 19.245  29.063  1   43.02  ? 133 LEU C CD1 1 
ATOM   7780 C CD2 . LEU D 2 137 ? -44.316 17.055  28.933  1   40.32  ? 133 LEU C CD2 1 
ATOM   7781 N N   . LEU D 2 138 ? -39.878 18.944  27.206  1   42.19  ? 134 LEU C N   1 
ATOM   7782 C CA  . LEU D 2 138 ? -38.662 19.563  26.709  1   42.36  ? 134 LEU C CA  1 
ATOM   7783 C C   . LEU D 2 138 ? -38.899 20.121  25.311  1   44.2   ? 134 LEU C C   1 
ATOM   7784 O O   . LEU D 2 138 ? -39.499 19.446  24.463  1   45.69  ? 134 LEU C O   1 
ATOM   7785 C CB  . LEU D 2 138 ? -37.584 18.483  26.721  1   42.09  ? 134 LEU C CB  1 
ATOM   7786 C CG  . LEU D 2 138 ? -37.362 17.82   28.08   1   42.18  ? 134 LEU C CG  1 
ATOM   7787 C CD1 . LEU D 2 138 ? -36.306 16.764  27.931  1   42.71  ? 134 LEU C CD1 1 
ATOM   7788 C CD2 . LEU D 2 138 ? -36.956 18.825  29.14   1   40.95  ? 134 LEU C CD2 1 
ATOM   7789 N N   . ILE D 2 139 ? -38.427 21.356  25.087  1   43.44  ? 135 ILE C N   1 
ATOM   7790 C CA  . ILE D 2 139 ? -38.52  21.99   23.782  1   45.2   ? 135 ILE C CA  1 
ATOM   7791 C C   . ILE D 2 139 ? -37.12  22.166  23.175  1   47.67  ? 135 ILE C C   1 
ATOM   7792 O O   . ILE D 2 139 ? -36.116 22.315  23.891  1   46.47  ? 135 ILE C O   1 
ATOM   7793 C CB  . ILE D 2 139 ? -39.216 23.362  23.89   1   45.38  ? 135 ILE C CB  1 
ATOM   7794 C CG1 . ILE D 2 139 ? -38.427 24.325  24.793  1   45.07  ? 135 ILE C CG1 1 
ATOM   7795 C CG2 . ILE D 2 139 ? -40.678 23.212  24.322  1   45.43  ? 135 ILE C CG2 1 
ATOM   7796 C CD1 . ILE D 2 139 ? -38.74  25.785  24.568  1   46.83  ? 135 ILE C CD1 1 
ATOM   7797 N N   . ASN D 2 140 ? -37.079 22.221  21.834  1   49.11  ? 136 ASN C N   1 
ATOM   7798 C CA  . ASN D 2 140 ? -35.877 22.618  21.113  1   53.88  ? 136 ASN C CA  1 
ATOM   7799 C C   . ASN D 2 140 ? -36.144 23.951  20.425  1   57.51  ? 136 ASN C C   1 
ATOM   7800 O O   . ASN D 2 140 ? -37.214 24.561  20.623  1   58.32  ? 136 ASN C O   1 
ATOM   7801 C CB  . ASN D 2 140 ? -35.391 21.534  20.149  1   55.46  ? 136 ASN C CB  1 
ATOM   7802 C CG  . ASN D 2 140 ? -36.368 21.226  19.026  1   56.9   ? 136 ASN C CG  1 
ATOM   7803 O OD1 . ASN D 2 140 ? -37.302 21.991  18.742  1   60.91  ? 136 ASN C OD1 1 
ATOM   7804 N ND2 . ASN D 2 140 ? -36.164 20.108  18.359  1   55.82  ? 136 ASN C ND2 1 
ATOM   7805 N N   . THR D 2 141 ? -35.175 24.354  19.588  1   58.75  ? 137 THR C N   1 
ATOM   7806 C CA  . THR D 2 141 ? -35.227 25.642  18.907  1   62.45  ? 137 THR C CA  1 
ATOM   7807 C C   . THR D 2 141 ? -36.043 25.576  17.616  1   63.04  ? 137 THR C C   1 
ATOM   7808 O O   . THR D 2 141 ? -36.287 26.612  16.99   1   64.22  ? 137 THR C O   1 
ATOM   7809 C CB  . THR D 2 141 ? -33.821 26.18   18.631  1   63.77  ? 137 THR C CB  1 
ATOM   7810 O OG1 . THR D 2 141 ? -33.242 25.287  17.689  1   64.22  ? 137 THR C OG1 1 
ATOM   7811 C CG2 . THR D 2 141 ? -32.965 26.266  19.878  1   61.51  ? 137 THR C CG2 1 
ATOM   7812 N N   . GLU D 2 142 ? -36.436 24.366  17.205  1   64.2   ? 138 GLU C N   1 
ATOM   7813 C CA  . GLU D 2 142 ? -37.112 24.179  15.925  1   69.98  ? 138 GLU C CA  1 
ATOM   7814 C C   . GLU D 2 142 ? -38.625 23.984  16.061  1   68.15  ? 138 GLU C C   1 
ATOM   7815 O O   . GLU D 2 142 ? -39.283 23.678  15.079  1   71.47  ? 138 GLU C O   1 
ATOM   7816 C CB  . GLU D 2 142 ? -36.405 23.082  15.128  1   70.96  ? 138 GLU C CB  1 
ATOM   7817 C CG  . GLU D 2 142 ? -35.071 23.587  14.585  1   81.2   ? 138 GLU C CG  1 
ATOM   7818 C CD  . GLU D 2 142 ? -34.483 22.852  13.406  1   94.98  ? 138 GLU C CD  1 
ATOM   7819 O OE1 . GLU D 2 142 ? -34.973 21.74   13.109  1   96.32  ? 138 GLU C OE1 1 
ATOM   7820 O OE2 . GLU D 2 142 ? -33.564 23.429  12.777  1   101.89 ? 138 GLU C OE2 1 
ATOM   7821 N N   . GLY D 2 143 ? -39.171 24.133  17.272  1   61.93  ? 139 GLY C N   1 
ATOM   7822 C CA  . GLY D 2 143 ? -40.61  24.168  17.449  1   56.87  ? 139 GLY C CA  1 
ATOM   7823 C C   . GLY D 2 143 ? -41.186 22.838  17.923  1   54.01  ? 139 GLY C C   1 
ATOM   7824 O O   . GLY D 2 143 ? -42.406 22.715  18.038  1   54.82  ? 139 GLY C O   1 
ATOM   7825 N N   . ALA D 2 144 ? -40.316 21.854  18.198  1   50.97  ? 140 ALA C N   1 
ATOM   7826 C CA  . ALA D 2 144 ? -40.755 20.566  18.72   1   48.82  ? 140 ALA C CA  1 
ATOM   7827 C C   . ALA D 2 144 ? -40.897 20.622  20.247  1   47.03  ? 140 ALA C C   1 
ATOM   7828 O O   . ALA D 2 144 ? -40.309 21.512  20.867  1   46.69  ? 140 ALA C O   1 
ATOM   7829 C CB  . ALA D 2 144 ? -39.779 19.497  18.285  1   48.64  ? 140 ALA C CB  1 
ATOM   7830 N N   . ILE D 2 145 ? -41.697 19.69   20.81   1   45.53  ? 141 ILE C N   1 
ATOM   7831 C CA  . ILE D 2 145 ? -41.81  19.451  22.251  1   45.45  ? 141 ILE C CA  1 
ATOM   7832 C C   . ILE D 2 145 ? -41.898 17.95   22.508  1   43.34  ? 141 ILE C C   1 
ATOM   7833 O O   . ILE D 2 145 ? -42.416 17.226  21.68   1   43.16  ? 141 ILE C O   1 
ATOM   7834 C CB  . ILE D 2 145 ? -42.992 20.212  22.896  1   46.37  ? 141 ILE C CB  1 
ATOM   7835 C CG1 . ILE D 2 145 ? -42.999 20.089  24.417  1   45.76  ? 141 ILE C CG1 1 
ATOM   7836 C CG2 . ILE D 2 145 ? -44.334 19.786  22.304  1   45.3   ? 141 ILE C CG2 1 
ATOM   7837 C CD1 . ILE D 2 145 ? -43.926 21.088  25.099  1   45.57  ? 141 ILE C CD1 1 
ATOM   7838 N N   . LYS D 2 146 ? -41.372 17.481  23.642  1   43.49  ? 142 LYS C N   1 
ATOM   7839 C CA  . LYS D 2 146 ? -41.262 16.05   23.879  1   42.33  ? 142 LYS C CA  1 
ATOM   7840 C C   . LYS D 2 146 ? -41.502 15.717  25.351  1   42.26  ? 142 LYS C C   1 
ATOM   7841 O O   . LYS D 2 146 ? -41.055 16.437  26.248  1   43.22  ? 142 LYS C O   1 
ATOM   7842 C CB  . LYS D 2 146 ? -39.872 15.525  23.505  1   44.33  ? 142 LYS C CB  1 
ATOM   7843 C CG  . LYS D 2 146 ? -39.447 15.861  22.073  1   46.81  ? 142 LYS C CG  1 
ATOM   7844 C CD  . LYS D 2 146 ? -38.304 15.008  21.54   1   44.78  ? 142 LYS C CD  1 
ATOM   7845 C CE  . LYS D 2 146 ? -37.779 15.529  20.206  1   45.79  ? 142 LYS C CE  1 
ATOM   7846 N NZ  . LYS D 2 146 ? -36.965 14.52   19.513  1   43.24  ? 142 LYS C NZ  1 
ATOM   7847 N N   . LEU D 2 147 ? -42.185 14.594  25.579  1   40.64  ? 143 LEU C N   1 
ATOM   7848 C CA  . LEU D 2 147 ? -42.358 14.059  26.905  1   41.56  ? 143 LEU C CA  1 
ATOM   7849 C C   . LEU D 2 147 ? -40.997 13.588  27.396  1   43.02  ? 143 LEU C C   1 
ATOM   7850 O O   . LEU D 2 147 ? -40.303 12.862  26.672  1   45.61  ? 143 LEU C O   1 
ATOM   7851 C CB  . LEU D 2 147 ? -43.308 12.859  26.892  1   40.88  ? 143 LEU C CB  1 
ATOM   7852 C CG  . LEU D 2 147 ? -44.678 12.998  26.235  1   43.25  ? 143 LEU C CG  1 
ATOM   7853 C CD1 . LEU D 2 147 ? -45.622 11.878  26.699  1   44.23  ? 143 LEU C CD1 1 
ATOM   7854 C CD2 . LEU D 2 147 ? -45.285 14.325  26.497  1   43.06  ? 143 LEU C CD2 1 
ATOM   7855 N N   . ALA D 2 148 ? -40.67  13.901  28.654  1   41.87  ? 144 ALA C N   1 
ATOM   7856 C CA  . ALA D 2 148 ? -39.445 13.364  29.249  1   44.08  ? 144 ALA C CA  1 
ATOM   7857 C C   . ALA D 2 148 ? -39.672 12.917  30.694  1   44.63  ? 144 ALA C C   1 
ATOM   7858 O O   . ALA D 2 148 ? -40.79  12.994  31.19   1   45.16  ? 144 ALA C O   1 
ATOM   7859 C CB  . ALA D 2 148 ? -38.326 14.379  29.143  1   42.16  ? 144 ALA C CB  1 
ATOM   7860 N N   . ASP D 2 149 ? -38.604 12.445  31.351  1   45.03  ? 145 ASP C N   1 
ATOM   7861 C CA  . ASP D 2 149 ? -38.624 11.943  32.721  1   46.97  ? 145 ASP C CA  1 
ATOM   7862 C C   . ASP D 2 149 ? -39.685 10.853  32.914  1   45.54  ? 145 ASP C C   1 
ATOM   7863 O O   . ASP D 2 149 ? -40.736 11.084  33.514  1   46.89  ? 145 ASP C O   1 
ATOM   7864 C CB  . ASP D 2 149 ? -38.681 13.052  33.77   1   49.62  ? 145 ASP C CB  1 
ATOM   7865 C CG  . ASP D 2 149 ? -38.282 12.615  35.182  1   57.79  ? 145 ASP C CG  1 
ATOM   7866 O OD1 . ASP D 2 149 ? -38.15  11.371  35.439  1   57.48  ? 145 ASP C OD1 1 
ATOM   7867 O OD2 . ASP D 2 149 ? -38.042 13.524  36.014  1   63.01  ? 145 ASP C OD2 1 
ATOM   7868 N N   . PHE D 2 150 ? -39.364 9.651   32.448  1   41.82  ? 146 PHE C N   1 
ATOM   7869 C CA  . PHE D 2 150 ? -40.215 8.496   32.616  1   40.56  ? 146 PHE C CA  1 
ATOM   7870 C C   . PHE D 2 150 ? -39.853 7.689   33.861  1   43.17  ? 146 PHE C C   1 
ATOM   7871 O O   . PHE D 2 150 ? -40.146 6.496   33.942  1   42.85  ? 146 PHE C O   1 
ATOM   7872 C CB  . PHE D 2 150 ? -40.088 7.629   31.368  1   39.34  ? 146 PHE C CB  1 
ATOM   7873 C CG  . PHE D 2 150 ? -40.878 8.161   30.188  1   38.13  ? 146 PHE C CG  1 
ATOM   7874 C CD1 . PHE D 2 150 ? -40.469 9.323   29.527  1   36.23  ? 146 PHE C CD1 1 
ATOM   7875 C CD2 . PHE D 2 150 ? -42.041 7.503   29.77   1   36.99  ? 146 PHE C CD2 1 
ATOM   7876 C CE1 . PHE D 2 150 ? -41.191 9.804   28.433  1   37.29  ? 146 PHE C CE1 1 
ATOM   7877 C CE2 . PHE D 2 150 ? -42.76  7.971   28.661  1   37.94  ? 146 PHE C CE2 1 
ATOM   7878 C CZ  . PHE D 2 150 ? -42.345 9.128   27.987  1   37.83  ? 146 PHE C CZ  1 
ATOM   7879 N N   . GLY D 2 151 ? -39.291 8.33    34.871  1   47.49  ? 147 GLY C N   1 
ATOM   7880 C CA  . GLY D 2 151 ? -38.959 7.62    36.116  1   50.84  ? 147 GLY C CA  1 
ATOM   7881 C C   . GLY D 2 151 ? -40.192 7.181   36.872  1   53.45  ? 147 GLY C C   1 
ATOM   7882 O O   . GLY D 2 151 ? -40.125 6.141   37.543  1   52.26  ? 147 GLY C O   1 
ATOM   7883 N N   . LEU D 2 152 ? -41.282 7.937   36.761  1   52.96  ? 148 LEU C N   1 
ATOM   7884 C CA  . LEU D 2 152 ? -42.523 7.62    37.505  1   53.64  ? 148 LEU C CA  1 
ATOM   7885 C C   . LEU D 2 152 ? -43.5   6.904   36.574  1   51.41  ? 148 LEU C C   1 
ATOM   7886 O O   . LEU D 2 152 ? -44.69  6.851   36.902  1   55.52  ? 148 LEU C O   1 
ATOM   7887 C CB  . LEU D 2 152 ? -43.103 8.924   38.039  1   55.59  ? 148 LEU C CB  1 
ATOM   7888 C CG  . LEU D 2 152 ? -42.417 9.516   39.272  1   65.52  ? 148 LEU C CG  1 
ATOM   7889 C CD1 . LEU D 2 152 ? -43.325 10.542  39.917  1   60.62  ? 148 LEU C CD1 1 
ATOM   7890 C CD2 . LEU D 2 152 ? -42.071 8.423   40.261  1   70.22  ? 148 LEU C CD2 1 
ATOM   7891 N N   . ALA D 2 153 ? -43     6.363   35.468  1   47.76  ? 149 ALA C N   1 
ATOM   7892 C CA  . ALA D 2 153 ? -43.877 5.726   34.466  1   43.58  ? 149 ALA C CA  1 
ATOM   7893 C C   . ALA D 2 153 ? -44.152 4.275   34.828  1   44.56  ? 149 ALA C C   1 
ATOM   7894 O O   . ALA D 2 153 ? -43.482 3.73    35.712  1   44.46  ? 149 ALA C O   1 
ATOM   7895 C CB  . ALA D 2 153 ? -43.265 5.844   33.102  1   40.92  ? 149 ALA C CB  1 
ATOM   7896 N N   . ARG D 2 154 ? -45.087 3.665   34.109  1   45.17  ? 150 ARG C N   1 
ATOM   7897 C CA  . ARG D 2 154 ? -45.508 2.314   34.427  1   46.3   ? 150 ARG C CA  1 
ATOM   7898 C C   . ARG D 2 154 ? -46.142 1.67    33.191  1   47.06  ? 150 ARG C C   1 
ATOM   7899 O O   . ARG D 2 154 ? -46.991 2.272   32.522  1   49.69  ? 150 ARG C O   1 
ATOM   7900 C CB  . ARG D 2 154 ? -46.404 2.486   35.66   1   46.75  ? 150 ARG C CB  1 
ATOM   7901 C CG  . ARG D 2 154 ? -47.399 1.37    35.912  1   49.76  ? 150 ARG C CG  1 
ATOM   7902 C CD  . ARG D 2 154 ? -46.894 0.13    36.577  1   49.81  ? 150 ARG C CD  1 
ATOM   7903 N NE  . ARG D 2 154 ? -46.93  0.193   38.044  1   50.44  ? 150 ARG C NE  1 
ATOM   7904 C CZ  . ARG D 2 154 ? -46.831 -0.919  38.774  1   48.65  ? 150 ARG C CZ  1 
ATOM   7905 N NH1 . ARG D 2 154 ? -46.745 -0.859  40.089  1   46.64  ? 150 ARG C NH1 1 
ATOM   7906 N NH2 . ARG D 2 154 ? -46.808 -2.087  38.151  1   48.15  ? 150 ARG C NH2 1 
ATOM   7907 N N   . ALA D 2 155 ? -45.672 0.466   32.871  1   45.31  ? 151 ALA C N   1 
ATOM   7908 C CA  . ALA D 2 155 ? -46.29  -0.368  31.854  1   48.81  ? 151 ALA C CA  1 
ATOM   7909 C C   . ALA D 2 155 ? -47.546 -1      32.474  1   50.61  ? 151 ALA C C   1 
ATOM   7910 O O   . ALA D 2 155 ? -47.437 -1.7    33.477  1   49.79  ? 151 ALA C O   1 
ATOM   7911 C CB  . ALA D 2 155 ? -45.308 -1.437  31.361  1   44.26  ? 151 ALA C CB  1 
ATOM   7912 N N   . PHE D 2 156 ? -48.732 -0.729  31.909  1   50.87  ? 152 PHE C N   1 
ATOM   7913 C CA  . PHE D 2 156 ? -49.978 -1.199  32.521  1   53.75  ? 152 PHE C CA  1 
ATOM   7914 C C   . PHE D 2 156 ? -50.544 -2.375  31.727  1   54.48  ? 152 PHE C C   1 
ATOM   7915 O O   . PHE D 2 156 ? -50.233 -2.545  30.547  1   55.62  ? 152 PHE C O   1 
ATOM   7916 C CB  . PHE D 2 156 ? -51.015 -0.08   32.666  1   50.5   ? 152 PHE C CB  1 
ATOM   7917 C CG  . PHE D 2 156 ? -51.513 0.54    31.369  1   50.94  ? 152 PHE C CG  1 
ATOM   7918 C CD1 . PHE D 2 156 ? -50.856 1.643   30.822  1   48.94  ? 152 PHE C CD1 1 
ATOM   7919 C CD2 . PHE D 2 156 ? -52.664 0.055   30.719  1   49.91  ? 152 PHE C CD2 1 
ATOM   7920 C CE1 . PHE D 2 156 ? -51.328 2.226   29.635  1   47.82  ? 152 PHE C CE1 1 
ATOM   7921 C CE2 . PHE D 2 156 ? -53.129 0.639   29.546  1   48     ? 152 PHE C CE2 1 
ATOM   7922 C CZ  . PHE D 2 156 ? -52.462 1.728   29.006  1   47.2   ? 152 PHE C CZ  1 
ATOM   7923 N N   . GLY D 2 157 ? -51.449 -3.132  32.355  1   56.95  ? 153 GLY C N   1 
ATOM   7924 C CA  . GLY D 2 157 ? -52.133 -4.227  31.636  1   57.09  ? 153 GLY C CA  1 
ATOM   7925 C C   . GLY D 2 157 ? -53.566 -3.829  31.326  1   59.75  ? 153 GLY C C   1 
ATOM   7926 O O   . GLY D 2 157 ? -53.983 -2.74   31.775  1   60.48  ? 153 GLY C O   1 
ATOM   7927 N N   . VAL D 2 158 ? -54.298 -4.666  30.583  1   59.16  ? 154 VAL C N   1 
ATOM   7928 C CA  . VAL D 2 158 ? -55.723 -4.37   30.238  1   57.43  ? 154 VAL C CA  1 
ATOM   7929 C C   . VAL D 2 158 ? -56.604 -5.517  30.764  1   59.48  ? 154 VAL C C   1 
ATOM   7930 O O   . VAL D 2 158 ? -56.451 -6.647  30.261  1   63.1   ? 154 VAL C O   1 
ATOM   7931 C CB  . VAL D 2 158 ? -55.931 -4.164  28.725  1   58.81  ? 154 VAL C CB  1 
ATOM   7932 C CG1 . VAL D 2 158 ? -57.345 -3.693  28.405  1   60.92  ? 154 VAL C CG1 1 
ATOM   7933 C CG2 . VAL D 2 158 ? -54.899 -3.214  28.13   1   55.74  ? 154 VAL C CG2 1 
ATOM   7934 N N   . PRO D 2 159 ? -57.514 -5.286  31.738  1   59.21  ? 155 PRO C N   1 
ATOM   7935 C CA  . PRO D 2 159 ? -57.733 -3.959  32.3    1   57.16  ? 155 PRO C CA  1 
ATOM   7936 C C   . PRO D 2 159 ? -56.69  -3.548  33.335  1   56.92  ? 155 PRO C C   1 
ATOM   7937 O O   . PRO D 2 159 ? -55.849 -4.386  33.722  1   59.74  ? 155 PRO C O   1 
ATOM   7938 C CB  . PRO D 2 159 ? -59.133 -4.104  32.915  1   57.15  ? 155 PRO C CB  1 
ATOM   7939 C CG  . PRO D 2 159 ? -59.175 -5.542  33.37   1   56.82  ? 155 PRO C CG  1 
ATOM   7940 C CD  . PRO D 2 159 ? -58.385 -6.298  32.315  1   57.76  ? 155 PRO C CD  1 
ATOM   7941 N N   . VAL D 2 160 ? -56.77  -2.305  33.809  1   55.52  ? 156 VAL C N   1 
ATOM   7942 C CA  . VAL D 2 160 ? -55.733 -1.766  34.739  1   53.51  ? 156 VAL C CA  1 
ATOM   7943 C C   . VAL D 2 160 ? -55.916 -2.361  36.136  1   56.4   ? 156 VAL C C   1 
ATOM   7944 O O   . VAL D 2 160 ? -57.045 -2.747  36.474  1   61.42  ? 156 VAL C O   1 
ATOM   7945 C CB  . VAL D 2 160 ? -55.731 -0.226  34.793  1   50.53  ? 156 VAL C CB  1 
ATOM   7946 C CG1 . VAL D 2 160 ? -55.555 0.393   33.414  1   48.22  ? 156 VAL C CG1 1 
ATOM   7947 C CG2 . VAL D 2 160 ? -56.955 0.338   35.498  1   49.3   ? 156 VAL C CG2 1 
ATOM   7948 N N   . ARG D 2 161 ? -54.831 -2.428  36.895  1   58.58  ? 157 ARG C N   1 
ATOM   7949 C CA  . ARG D 2 161 ? -54.893 -2.935  38.286  1   62.82  ? 157 ARG C CA  1 
ATOM   7950 C C   . ARG D 2 161 ? -54.499 -1.791  39.229  1   60.1   ? 157 ARG C C   1 
ATOM   7951 O O   . ARG D 2 161 ? -54.306 -0.666  38.742  1   58.73  ? 157 ARG C O   1 
ATOM   7952 C CB  . ARG D 2 161 ? -54.003 -4.175  38.424  1   65.28  ? 157 ARG C CB  1 
ATOM   7953 C CG  . ARG D 2 161 ? -52.524 -3.963  38.707  1   73.71  ? 157 ARG C CG  1 
ATOM   7954 C CD  . ARG D 2 161 ? -51.886 -5.152  39.399  1   80.49  ? 157 ARG C CD  1 
ATOM   7955 N NE  . ARG D 2 161 ? -50.927 -4.74   40.428  1   89.58  ? 157 ARG C NE  1 
ATOM   7956 C CZ  . ARG D 2 161 ? -49.653 -4.455  40.197  1   89.93  ? 157 ARG C CZ  1 
ATOM   7957 N NH1 . ARG D 2 161 ? -49.026 -5.024  39.186  1   85.41  ? 157 ARG C NH1 1 
ATOM   7958 N NH2 . ARG D 2 161 ? -49.013 -3.604  40.978  1   83.51  ? 157 ARG C NH2 1 
ATOM   7959 N N   . THR D 2 162 ? -54.411 -2.072  40.526  1   60.79  ? 158 THR C N   1 
ATOM   7960 C CA  . THR D 2 162 ? -54.046 -1.031  41.506  1   62.37  ? 158 THR C CA  1 
ATOM   7961 C C   . THR D 2 162 ? -52.563 -0.749  41.425  1   59.03  ? 158 THR C C   1 
ATOM   7962 O O   . THR D 2 162 ? -51.767 -1.684  41.613  1   58.76  ? 158 THR C O   1 
ATOM   7963 C CB  . THR D 2 162 ? -54.503 -1.415  42.91   1   65.26  ? 158 THR C CB  1 
ATOM   7964 O OG1 . THR D 2 162 ? -55.921 -1.405  42.81   1   75.33  ? 158 THR C OG1 1 
ATOM   7965 C CG2 . THR D 2 162 ? -54.056 -0.42   43.964  1   62     ? 158 THR C CG2 1 
ATOM   7966 N N   . TYR D 2 163 ? -52.209 0.498   41.139  1   56     ? 159 TYR C N   1 
ATOM   7967 C CA  . TYR D 2 163 ? -50.83  0.94    41.029  1   54.31  ? 159 TYR C CA  1 
ATOM   7968 C C   . TYR D 2 163 ? -50.532 1.916   42.163  1   56.72  ? 159 TYR C C   1 
ATOM   7969 O O   . TYR D 2 163 ? -51.346 2.09    43.065  1   57.35  ? 159 TYR C O   1 
ATOM   7970 C CB  . TYR D 2 163 ? -50.61  1.574   39.656  1   54.17  ? 159 TYR C CB  1 
ATOM   7971 C CG  . TYR D 2 163 ? -50.959 0.69    38.473  1   54.3   ? 159 TYR C CG  1 
ATOM   7972 C CD1 . TYR D 2 163 ? -50.565 -0.648  38.448  1   55.46  ? 159 TYR C CD1 1 
ATOM   7973 C CD2 . TYR D 2 163 ? -51.666 1.189   37.391  1   52.47  ? 159 TYR C CD2 1 
ATOM   7974 C CE1 . TYR D 2 163 ? -50.861 -1.47   37.378  1   55.33  ? 159 TYR C CE1 1 
ATOM   7975 C CE2 . TYR D 2 163 ? -51.976 0.369   36.32   1   54.22  ? 159 TYR C CE2 1 
ATOM   7976 C CZ  . TYR D 2 163 ? -51.58  -0.963  36.309  1   55.56  ? 159 TYR C CZ  1 
ATOM   7977 O OH  . TYR D 2 163 ? -51.874 -1.807  35.257  1   56.95  ? 159 TYR C OH  1 
HETATM 7978 N N   . TPO D 2 164 ? -49.327 2.515   42.153  1   58.55  ? 160 TPO C N   1 
HETATM 7979 C CA  . TPO D 2 164 ? -48.88  3.377   43.242  1   57.18  ? 160 TPO C CA  1 
HETATM 7980 C CB  . TPO D 2 164 ? -47.423 3.789   42.981  1   55.37  ? 160 TPO C CB  1 
HETATM 7981 C CG2 . TPO D 2 164 ? -46.822 4.62    44.1    1   57.68  ? 160 TPO C CG2 1 
HETATM 7982 O OG1 . TPO D 2 164 ? -46.628 2.556   42.829  1   52.22  ? 160 TPO C OG1 1 
HETATM 7983 P P   . TPO D 2 164 ? -45.94  2.24    41.406  1   49.26  ? 160 TPO C P   1 
HETATM 7984 O O1P . TPO D 2 164 ? -47.033 1.955   40.409  1   53.49  ? 160 TPO C O1P 1 
HETATM 7985 O O2P . TPO D 2 164 ? -45.057 1.063   41.658  1   50.26  ? 160 TPO C O2P 1 
HETATM 7986 O O3P . TPO D 2 164 ? -45.182 3.473   41.014  1   49.86  ? 160 TPO C O3P 1 
HETATM 7987 C C   . TPO D 2 164 ? -49.808 4.593   43.32   1   59.41  ? 160 TPO C C   1 
HETATM 7988 O O   . TPO D 2 164 ? -50.104 5.19    42.279  1   57.82  ? 160 TPO C O   1 
ATOM   7989 N N   . HIS D 2 165 ? -50.267 4.953   44.531  1   62.4   ? 161 HIS C N   1 
ATOM   7990 C CA  . HIS D 2 165 ? -51.148 6.107   44.692  1   73.56  ? 161 HIS C CA  1 
ATOM   7991 C C   . HIS D 2 165 ? -50.36  7.428   44.765  1   75     ? 161 HIS C C   1 
ATOM   7992 O O   . HIS D 2 165 ? -50.832 8.484   44.336  1   71.38  ? 161 HIS C O   1 
ATOM   7993 C CB  . HIS D 2 165 ? -52.118 5.892   45.864  1   88     ? 161 HIS C CB  1 
ATOM   7994 C CG  . HIS D 2 165 ? -52.649 7.164   46.471  1   110.91 ? 161 HIS C CG  1 
ATOM   7995 N ND1 . HIS D 2 165 ? -53.967 7.565   46.367  1   120.64 ? 161 HIS C ND1 1 
ATOM   7996 C CD2 . HIS D 2 165 ? -52.036 8.121   47.219  1   115.39 ? 161 HIS C CD2 1 
ATOM   7997 C CE1 . HIS D 2 165 ? -54.137 8.717   47.015  1   121.83 ? 161 HIS C CE1 1 
ATOM   7998 N NE2 . HIS D 2 165 ? -52.979 9.079   47.533  1   117.05 ? 161 HIS C NE2 1 
ATOM   7999 N N   . GLU D 2 166 ? -49.162 7.393   45.354  1   80.38  ? 162 GLU C N   1 
ATOM   8000 C CA  . GLU D 2 166 ? -48.356 8.603   45.497  1   86.36  ? 162 GLU C CA  1 
ATOM   8001 C C   . GLU D 2 166 ? -47.798 8.961   44.118  1   87.78  ? 162 GLU C C   1 
ATOM   8002 O O   . GLU D 2 166 ? -46.618 8.713   43.863  1   95.43  ? 162 GLU C O   1 
ATOM   8003 C CB  . GLU D 2 166 ? -47.171 8.447   46.465  1   84.99  ? 162 GLU C CB  1 
ATOM   8004 C CG  . GLU D 2 166 ? -47.518 8.17    47.931  1   94.39  ? 162 GLU C CG  1 
ATOM   8005 C CD  . GLU D 2 166 ? -48.3   6.902   48.292  1   99.28  ? 162 GLU C CD  1 
ATOM   8006 O OE1 . GLU D 2 166 ? -49.308 7.037   49.038  1   95.89  ? 162 GLU C OE1 1 
ATOM   8007 O OE2 . GLU D 2 166 ? -47.926 5.784   47.833  1   95.05  ? 162 GLU C OE2 1 
ATOM   8008 N N   . VAL D 2 167 ? -48.642 9.496   43.216  1   77.04  ? 163 VAL C N   1 
ATOM   8009 C CA  . VAL D 2 167 ? -48.21  9.73    41.841  1   68.79  ? 163 VAL C CA  1 
ATOM   8010 C C   . VAL D 2 167 ? -48.751 11.064  41.35   1   64.68  ? 163 VAL C C   1 
ATOM   8011 O O   . VAL D 2 167 ? -49.84  11.488  41.768  1   62.84  ? 163 VAL C O   1 
ATOM   8012 C CB  . VAL D 2 167 ? -48.551 8.632   40.813  1   68.72  ? 163 VAL C CB  1 
ATOM   8013 C CG1 . VAL D 2 167 ? -47.709 7.384   41.029  1   65.39  ? 163 VAL C CG1 1 
ATOM   8014 C CG2 . VAL D 2 167 ? -50.043 8.295   40.783  1   62.94  ? 163 VAL C CG2 1 
ATOM   8015 N N   . VAL D 2 168 ? -47.962 11.675  40.451  1   56.02  ? 164 VAL C N   1 
ATOM   8016 C CA  . VAL D 2 168 ? -48.27  12.962  39.853  1   56.33  ? 164 VAL C CA  1 
ATOM   8017 C C   . VAL D 2 168 ? -48.02  14.057  40.893  1   57.03  ? 164 VAL C C   1 
ATOM   8018 O O   . VAL D 2 168 ? -48.487 13.985  42.029  1   58.05  ? 164 VAL C O   1 
ATOM   8019 C CB  . VAL D 2 168 ? -49.68  13.095  39.222  1   58.18  ? 164 VAL C CB  1 
ATOM   8020 C CG1 . VAL D 2 168 ? -49.807 14.373  38.415  1   55.8   ? 164 VAL C CG1 1 
ATOM   8021 C CG2 . VAL D 2 168 ? -50.072 11.917  38.325  1   57.97  ? 164 VAL C CG2 1 
ATOM   8022 N N   . THR D 2 169 ? -47.26  15.079  40.488  1   56.03  ? 165 THR C N   1 
ATOM   8023 C CA  . THR D 2 169 ? -47.119 16.319  41.241  1   56.17  ? 165 THR C CA  1 
ATOM   8024 C C   . THR D 2 169 ? -48.517 16.905  41.506  1   53.71  ? 165 THR C C   1 
ATOM   8025 O O   . THR D 2 169 ? -49.37  16.943  40.609  1   54.86  ? 165 THR C O   1 
ATOM   8026 C CB  . THR D 2 169 ? -46.176 17.242  40.445  1   55.48  ? 165 THR C CB  1 
ATOM   8027 O OG1 . THR D 2 169 ? -44.974 16.489  40.262  1   61.3   ? 165 THR C OG1 1 
ATOM   8028 C CG2 . THR D 2 169 ? -45.878 18.573  41.121  1   51.02  ? 165 THR C CG2 1 
ATOM   8029 N N   . LEU D 2 170 ? -48.73  17.361  42.743  1   51.74  ? 166 LEU C N   1 
ATOM   8030 C CA  . LEU D 2 170 ? -50.027 17.75   43.283  1   53.33  ? 166 LEU C CA  1 
ATOM   8031 C C   . LEU D 2 170 ? -50.865 18.561  42.287  1   52.86  ? 166 LEU C C   1 
ATOM   8032 O O   . LEU D 2 170 ? -52.02  18.24   42.029  1   55.78  ? 166 LEU C O   1 
ATOM   8033 C CB  . LEU D 2 170 ? -49.769 18.525  44.575  1   52.65  ? 166 LEU C CB  1 
ATOM   8034 C CG  . LEU D 2 170 ? -51.007 18.998  45.343  1   57.65  ? 166 LEU C CG  1 
ATOM   8035 C CD1 . LEU D 2 170 ? -52     17.874  45.66   1   57.03  ? 166 LEU C CD1 1 
ATOM   8036 C CD2 . LEU D 2 170 ? -50.609 19.738  46.617  1   57.14  ? 166 LEU C CD2 1 
ATOM   8037 N N   . TRP D 2 171 ? -50.293 19.623  41.732  1   51.37  ? 167 TRP C N   1 
ATOM   8038 C CA  . TRP D 2 171 ? -51.015 20.566  40.885  1   51.39  ? 167 TRP C CA  1 
ATOM   8039 C C   . TRP D 2 171 ? -51.58  19.931  39.607  1   50.22  ? 167 TRP C C   1 
ATOM   8040 O O   . TRP D 2 171 ? -52.443 20.53   38.948  1   48.74  ? 167 TRP C O   1 
ATOM   8041 C CB  . TRP D 2 171 ? -50.064 21.703  40.497  1   50.49  ? 167 TRP C CB  1 
ATOM   8042 C CG  . TRP D 2 171 ? -49.638 22.575  41.637  1   53.54  ? 167 TRP C CG  1 
ATOM   8043 C CD1 . TRP D 2 171 ? -50.068 22.515  42.929  1   56.19  ? 167 TRP C CD1 1 
ATOM   8044 C CD2 . TRP D 2 171 ? -48.764 23.715  41.553  1   55.55  ? 167 TRP C CD2 1 
ATOM   8045 N NE1 . TRP D 2 171 ? -49.513 23.526  43.666  1   56.98  ? 167 TRP C NE1 1 
ATOM   8046 C CE2 . TRP D 2 171 ? -48.714 24.284  42.849  1   58.44  ? 167 TRP C CE2 1 
ATOM   8047 C CE3 . TRP D 2 171 ? -48.024 24.304  40.521  1   55.18  ? 167 TRP C CE3 1 
ATOM   8048 C CZ2 . TRP D 2 171 ? -47.942 25.414  43.129  1   59.13  ? 167 TRP C CZ2 1 
ATOM   8049 C CZ3 . TRP D 2 171 ? -47.261 25.412  40.803  1   57     ? 167 TRP C CZ3 1 
ATOM   8050 C CH2 . TRP D 2 171 ? -47.241 25.968  42.083  1   58.88  ? 167 TRP C CH2 1 
ATOM   8051 N N   . TYR D 2 172 ? -51.041 18.764  39.224  1   46.48  ? 168 TYR C N   1 
ATOM   8052 C CA  . TYR D 2 172 ? -51.356 18.14   37.951  1   45.08  ? 168 TYR C CA  1 
ATOM   8053 C C   . TYR D 2 172 ? -52.114 16.846  38.215  1   45.85  ? 168 TYR C C   1 
ATOM   8054 O O   . TYR D 2 172 ? -52.364 16.083  37.284  1   45.53  ? 168 TYR C O   1 
ATOM   8055 C CB  . TYR D 2 172 ? -50.046 17.916  37.181  1   44.27  ? 168 TYR C CB  1 
ATOM   8056 C CG  . TYR D 2 172 ? -49.35  19.247  36.973  1   44.24  ? 168 TYR C CG  1 
ATOM   8057 C CD1 . TYR D 2 172 ? -49.773 20.126  35.981  1   43.31  ? 168 TYR C CD1 1 
ATOM   8058 C CD2 . TYR D 2 172 ? -48.372 19.669  37.866  1   44.47  ? 168 TYR C CD2 1 
ATOM   8059 C CE1 . TYR D 2 172 ? -49.211 21.383  35.863  1   44.78  ? 168 TYR C CE1 1 
ATOM   8060 C CE2 . TYR D 2 172 ? -47.794 20.923  37.754  1   45.28  ? 168 TYR C CE2 1 
ATOM   8061 C CZ  . TYR D 2 172 ? -48.216 21.78   36.749  1   47.31  ? 168 TYR C CZ  1 
ATOM   8062 O OH  . TYR D 2 172 ? -47.618 23.014  36.658  1   49.6   ? 168 TYR C OH  1 
ATOM   8063 N N   . ARG D 2 173 ? -52.494 16.634  39.486  1   46.03  ? 169 ARG C N   1 
ATOM   8064 C CA  . ARG D 2 173 ? -53.064 15.388  39.968  1   46.53  ? 169 ARG C CA  1 
ATOM   8065 C C   . ARG D 2 173 ? -54.585 15.405  39.755  1   49.1   ? 169 ARG C C   1 
ATOM   8066 O O   . ARG D 2 173 ? -55.28  16.373  40.08   1   48.1   ? 169 ARG C O   1 
ATOM   8067 C CB  . ARG D 2 173 ? -52.712 15.207  41.449  1   46.82  ? 169 ARG C CB  1 
ATOM   8068 C CG  . ARG D 2 173 ? -52.993 13.803  41.958  1   48.53  ? 169 ARG C CG  1 
ATOM   8069 C CD  . ARG D 2 173 ? -52.578 13.623  43.391  1   51.63  ? 169 ARG C CD  1 
ATOM   8070 N NE  . ARG D 2 173 ? -51.136 13.809  43.579  1   55.1   ? 169 ARG C NE  1 
ATOM   8071 C CZ  . ARG D 2 173 ? -50.551 13.988  44.766  1   57.28  ? 169 ARG C CZ  1 
ATOM   8072 N NH1 . ARG D 2 173 ? -51.245 13.939  45.885  1   57.13  ? 169 ARG C NH1 1 
ATOM   8073 N NH2 . ARG D 2 173 ? -49.26  14.217  44.829  1   59.98  ? 169 ARG C NH2 1 
ATOM   8074 N N   . ALA D 2 174 ? -55.083 14.312  39.17   1   50.32  ? 170 ALA C N   1 
ATOM   8075 C CA  . ALA D 2 174 ? -56.467 14.194  38.737  1   50.26  ? 170 ALA C CA  1 
ATOM   8076 C C   . ALA D 2 174 ? -57.323 13.904  39.955  1   52.43  ? 170 ALA C C   1 
ATOM   8077 O O   . ALA D 2 174 ? -56.851 13.312  40.927  1   51.6   ? 170 ALA C O   1 
ATOM   8078 C CB  . ALA D 2 174 ? -56.6   13.085  37.74   1   47.55  ? 170 ALA C CB  1 
ATOM   8079 N N   . PRO D 2 175 ? -58.597 14.33   39.928  1   54.26  ? 171 PRO C N   1 
ATOM   8080 C CA  . PRO D 2 175 ? -59.469 14.194  41.089  1   56.88  ? 171 PRO C CA  1 
ATOM   8081 C C   . PRO D 2 175 ? -59.682 12.743  41.518  1   58.99  ? 171 PRO C C   1 
ATOM   8082 O O   . PRO D 2 175 ? -59.879 12.496  42.709  1   61.55  ? 171 PRO C O   1 
ATOM   8083 C CB  . PRO D 2 175 ? -60.769 14.877  40.628  1   59.96  ? 171 PRO C CB  1 
ATOM   8084 C CG  . PRO D 2 175 ? -60.735 14.793  39.105  1   58.36  ? 171 PRO C CG  1 
ATOM   8085 C CD  . PRO D 2 175 ? -59.254 14.937  38.761  1   55.83  ? 171 PRO C CD  1 
ATOM   8086 N N   . GLU D 2 176 ? -59.612 11.793  40.567  1   58.4   ? 172 GLU C N   1 
ATOM   8087 C CA  . GLU D 2 176 ? -59.732 10.375  40.892  1   58.97  ? 172 GLU C CA  1 
ATOM   8088 C C   . GLU D 2 176 ? -58.608 9.942   41.835  1   60.13  ? 172 GLU C C   1 
ATOM   8089 O O   . GLU D 2 176 ? -58.857 9.146   42.734  1   63.12  ? 172 GLU C O   1 
ATOM   8090 C CB  . GLU D 2 176 ? -59.866 9.437   39.687  1   58.04  ? 172 GLU C CB  1 
ATOM   8091 C CG  . GLU D 2 176 ? -58.73  9.495   38.665  1   55.79  ? 172 GLU C CG  1 
ATOM   8092 C CD  . GLU D 2 176 ? -58.96  10.416  37.471  1   56.81  ? 172 GLU C CD  1 
ATOM   8093 O OE1 . GLU D 2 176 ? -58.547 10.014  36.364  1   55.59  ? 172 GLU C OE1 1 
ATOM   8094 O OE2 . GLU D 2 176 ? -59.57  11.518  37.611  1   58.06  ? 172 GLU C OE2 1 
ATOM   8095 N N   . ILE D 2 177 ? -57.38  10.455  41.644  1   59.12  ? 173 ILE C N   1 
ATOM   8096 C CA  . ILE D 2 177 ? -56.267 10.081  42.521  1   61.27  ? 173 ILE C CA  1 
ATOM   8097 C C   . ILE D 2 177 ? -56.425 10.744  43.894  1   64.01  ? 173 ILE C C   1 
ATOM   8098 O O   . ILE D 2 177 ? -56.049 10.173  44.911  1   62.17  ? 173 ILE C O   1 
ATOM   8099 C CB  . ILE D 2 177 ? -54.899 10.423  41.897  1   61.24  ? 173 ILE C CB  1 
ATOM   8100 C CG1 . ILE D 2 177 ? -54.743 9.822   40.507  1   60.89  ? 173 ILE C CG1 1 
ATOM   8101 C CG2 . ILE D 2 177 ? -53.737 10.007  42.8    1   58.85  ? 173 ILE C CG2 1 
ATOM   8102 C CD1 . ILE D 2 177 ? -53.64  10.497  39.706  1   62.8   ? 173 ILE C CD1 1 
ATOM   8103 N N   . LEU D 2 178 ? -56.935 11.982  43.895  1   66.17  ? 174 LEU C N   1 
ATOM   8104 C CA  . LEU D 2 178 ? -57.11  12.792  45.089  1   67.11  ? 174 LEU C CA  1 
ATOM   8105 C C   . LEU D 2 178 ? -58.108 12.099  46.011  1   69.56  ? 174 LEU C C   1 
ATOM   8106 O O   . LEU D 2 178 ? -57.769 11.782  47.148  1   73.91  ? 174 LEU C O   1 
ATOM   8107 C CB  . LEU D 2 178 ? -57.574 14.204  44.705  1   67.42  ? 174 LEU C CB  1 
ATOM   8108 C CG  . LEU D 2 178 ? -56.512 15.181  44.166  1   63.66  ? 174 LEU C CG  1 
ATOM   8109 C CD1 . LEU D 2 178 ? -57.143 16.434  43.559  1   60.76  ? 174 LEU C CD1 1 
ATOM   8110 C CD2 . LEU D 2 178 ? -55.486 15.547  45.238  1   61.81  ? 174 LEU C CD2 1 
ATOM   8111 N N   . LEU D 2 179 ? -59.307 11.828  45.474  1   69.3   ? 175 LEU C N   1 
ATOM   8112 C CA  . LEU D 2 179 ? -60.415 11.188  46.162  1   70.75  ? 175 LEU C CA  1 
ATOM   8113 C C   . LEU D 2 179 ? -60.125 9.72    46.486  1   73.39  ? 175 LEU C C   1 
ATOM   8114 O O   . LEU D 2 179 ? -61.009 9.031   46.976  1   75.7   ? 175 LEU C O   1 
ATOM   8115 C CB  . LEU D 2 179 ? -61.639 11.32   45.263  1   69.84  ? 175 LEU C CB  1 
ATOM   8116 C CG  . LEU D 2 179 ? -62.134 12.741  44.995  1   71.77  ? 175 LEU C CG  1 
ATOM   8117 C CD1 . LEU D 2 179 ? -63.237 12.805  43.963  1   75.08  ? 175 LEU C CD1 1 
ATOM   8118 C CD2 . LEU D 2 179 ? -62.63  13.386  46.259  1   76.77  ? 175 LEU C CD2 1 
ATOM   8119 N N   . GLY D 2 180 ? -58.92  9.224   46.16   1   74.23  ? 176 GLY C N   1 
ATOM   8120 C CA  . GLY D 2 180 ? -58.377 7.985   46.708  1   72.04  ? 176 GLY C CA  1 
ATOM   8121 C C   . GLY D 2 180 ? -58.871 6.731   45.994  1   72.15  ? 176 GLY C C   1 
ATOM   8122 O O   . GLY D 2 180 ? -58.856 5.658   46.584  1   74.69  ? 176 GLY C O   1 
ATOM   8123 N N   . CYS D 2 181 ? -59.263 6.866   44.722  1   69.42  ? 177 CYS C N   1 
ATOM   8124 C CA  . CYS D 2 181 ? -59.832 5.766   43.959  1   68.11  ? 177 CYS C CA  1 
ATOM   8125 C C   . CYS D 2 181 ? -58.861 4.595   43.841  1   66.58  ? 177 CYS C C   1 
ATOM   8126 O O   . CYS D 2 181 ? -57.652 4.775   43.797  1   62.71  ? 177 CYS C O   1 
ATOM   8127 C CB  . CYS D 2 181 ? -60.266 6.215   42.571  1   71.55  ? 177 CYS C CB  1 
ATOM   8128 S SG  . CYS D 2 181 ? -61.708 7.314   42.617  1   85.07  ? 177 CYS C SG  1 
ATOM   8129 N N   . LYS D 2 182 ? -59.434 3.394   43.779  1   69.82  ? 178 LYS C N   1 
ATOM   8130 C CA  . LYS D 2 182 ? -58.717 2.131   43.678  1   73.25  ? 178 LYS C CA  1 
ATOM   8131 C C   . LYS D 2 182 ? -57.98  2.002   42.343  1   67.36  ? 178 LYS C C   1 
ATOM   8132 O O   . LYS D 2 182 ? -56.886 1.45    42.309  1   65.18  ? 178 LYS C O   1 
ATOM   8133 C CB  . LYS D 2 182 ? -59.71  0.964   43.797  1   82.06  ? 178 LYS C CB  1 
ATOM   8134 C CG  . LYS D 2 182 ? -59.061 -0.408  44.063  1   89.33  ? 178 LYS C CG  1 
ATOM   8135 C CD  . LYS D 2 182 ? -60.054 -1.532  44.342  1   91.37  ? 178 LYS C CD  1 
ATOM   8136 C CE  . LYS D 2 182 ? -59.409 -2.866  44.597  1   93.11  ? 178 LYS C CE  1 
ATOM   8137 N NZ  . LYS D 2 182 ? -60.414 -3.943  44.596  1   93.75  ? 178 LYS C NZ  1 
ATOM   8138 N N   . TYR D 2 183 ? -58.622 2.456   41.264  1   63.03  ? 179 TYR C N   1 
ATOM   8139 C CA  . TYR D 2 183 ? -58.101 2.307   39.921  1   61.5   ? 179 TYR C CA  1 
ATOM   8140 C C   . TYR D 2 183 ? -58.086 3.66    39.222  1   61.42  ? 179 TYR C C   1 
ATOM   8141 O O   . TYR D 2 183 ? -59.015 4.475   39.351  1   64.27  ? 179 TYR C O   1 
ATOM   8142 C CB  . TYR D 2 183 ? -58.915 1.384   39.009  1   63.68  ? 179 TYR C CB  1 
ATOM   8143 C CG  . TYR D 2 183 ? -59.129 -0.035  39.509  1   67.11  ? 179 TYR C CG  1 
ATOM   8144 C CD1 . TYR D 2 183 ? -58.06  -0.898  39.678  1   65.74  ? 179 TYR C CD1 1 
ATOM   8145 C CD2 . TYR D 2 183 ? -60.405 -0.526  39.771  1   70.4   ? 179 TYR C CD2 1 
ATOM   8146 C CE1 . TYR D 2 183 ? -58.232 -2.188  40.152  1   68.75  ? 179 TYR C CE1 1 
ATOM   8147 C CE2 . TYR D 2 183 ? -60.593 -1.822  40.225  1   70.78  ? 179 TYR C CE2 1 
ATOM   8148 C CZ  . TYR D 2 183 ? -59.506 -2.654  40.425  1   71.29  ? 179 TYR C CZ  1 
ATOM   8149 O OH  . TYR D 2 183 ? -59.677 -3.927  40.891  1   75.01  ? 179 TYR C OH  1 
ATOM   8150 N N   . TYR D 2 184 ? -56.993 3.868   38.484  1   57.92  ? 180 TYR C N   1 
ATOM   8151 C CA  . TYR D 2 184 ? -56.855 4.969   37.553  1   56.34  ? 180 TYR C CA  1 
ATOM   8152 C C   . TYR D 2 184 ? -56.147 4.431   36.314  1   53.76  ? 180 TYR C C   1 
ATOM   8153 O O   . TYR D 2 184 ? -55.548 3.354   36.345  1   52.04  ? 180 TYR C O   1 
ATOM   8154 C CB  . TYR D 2 184 ? -56.086 6.103   38.237  1   56.62  ? 180 TYR C CB  1 
ATOM   8155 C CG  . TYR D 2 184 ? -54.648 5.773   38.608  1   55.35  ? 180 TYR C CG  1 
ATOM   8156 C CD1 . TYR D 2 184 ? -53.652 5.691   37.634  1   54.51  ? 180 TYR C CD1 1 
ATOM   8157 C CD2 . TYR D 2 184 ? -54.276 5.564   39.935  1   56.3   ? 180 TYR C CD2 1 
ATOM   8158 C CE1 . TYR D 2 184 ? -52.338 5.379   37.967  1   52.25  ? 180 TYR C CE1 1 
ATOM   8159 C CE2 . TYR D 2 184 ? -52.959 5.267   40.281  1   54.52  ? 180 TYR C CE2 1 
ATOM   8160 C CZ  . TYR D 2 184 ? -51.988 5.171   39.295  1   53.58  ? 180 TYR C CZ  1 
ATOM   8161 O OH  . TYR D 2 184 ? -50.687 4.896   39.632  1   55.03  ? 180 TYR C OH  1 
ATOM   8162 N N   . SER D 2 185 ? -56.18  5.232   35.251  1   50.81  ? 181 SER C N   1 
ATOM   8163 C CA  . SER D 2 185 ? -55.832 4.763   33.927  1   50.1   ? 181 SER C CA  1 
ATOM   8164 C C   . SER D 2 185 ? -55.25  5.929   33.143  1   47.76  ? 181 SER C C   1 
ATOM   8165 O O   . SER D 2 185 ? -54.876 6.931   33.739  1   47.54  ? 181 SER C O   1 
ATOM   8166 C CB  . SER D 2 185 ? -57.069 4.211   33.25   1   51.89  ? 181 SER C CB  1 
ATOM   8167 O OG  . SER D 2 185 ? -56.732 3.515   32.059  1   54.04  ? 181 SER C OG  1 
ATOM   8168 N N   . THR D 2 186 ? -55.226 5.795   31.813  1   48.09  ? 182 THR C N   1 
ATOM   8169 C CA  . THR D 2 186 ? -54.748 6.82    30.9    1   47.82  ? 182 THR C CA  1 
ATOM   8170 C C   . THR D 2 186 ? -55.373 8.183   31.183  1   49.5   ? 182 THR C C   1 
ATOM   8171 O O   . THR D 2 186 ? -54.819 9.207   30.781  1   49.7   ? 182 THR C O   1 
ATOM   8172 C CB  . THR D 2 186 ? -55.03  6.403   29.46   1   48.75  ? 182 THR C CB  1 
ATOM   8173 O OG1 . THR D 2 186 ? -56.447 6.237   29.369  1   49.32  ? 182 THR C OG1 1 
ATOM   8174 C CG2 . THR D 2 186 ? -54.29  5.134   29.087  1   46.35  ? 182 THR C CG2 1 
ATOM   8175 N N   . ALA D 2 187 ? -56.533 8.215   31.85   1   52.13  ? 183 ALA C N   1 
ATOM   8176 C CA  . ALA D 2 187 ? -57.255 9.474   32.02   1   50.44  ? 183 ALA C CA  1 
ATOM   8177 C C   . ALA D 2 187 ? -56.435 10.483  32.826  1   48.11  ? 183 ALA C C   1 
ATOM   8178 O O   . ALA D 2 187 ? -56.485 11.673  32.524  1   47.99  ? 183 ALA C O   1 
ATOM   8179 C CB  . ALA D 2 187 ? -58.645 9.247   32.589  1   51.27  ? 183 ALA C CB  1 
ATOM   8180 N N   . VAL D 2 188 ? -55.658 9.997   33.808  1   47.67  ? 184 VAL C N   1 
ATOM   8181 C CA  . VAL D 2 188 ? -54.914 10.859  34.713  1   47.15  ? 184 VAL C CA  1 
ATOM   8182 C C   . VAL D 2 188 ? -53.872 11.671  33.944  1   46.8   ? 184 VAL C C   1 
ATOM   8183 O O   . VAL D 2 188 ? -53.575 12.8    34.342  1   50.36  ? 184 VAL C O   1 
ATOM   8184 C CB  . VAL D 2 188 ? -54.24  10.081  35.85   1   46.46  ? 184 VAL C CB  1 
ATOM   8185 C CG1 . VAL D 2 188 ? -55.206 9.087   36.486  1   46.63  ? 184 VAL C CG1 1 
ATOM   8186 C CG2 . VAL D 2 188 ? -52.959 9.42    35.356  1   45.62  ? 184 VAL C CG2 1 
ATOM   8187 N N   . ASP D 2 189 ? -53.346 11.121  32.843  1   43.99  ? 185 ASP C N   1 
ATOM   8188 C CA  . ASP D 2 189 ? -52.377 11.844  32.029  1   43.9   ? 185 ASP C CA  1 
ATOM   8189 C C   . ASP D 2 189 ? -53.037 12.973  31.248  1   43.62  ? 185 ASP C C   1 
ATOM   8190 O O   . ASP D 2 189 ? -52.433 14.038  31.062  1   43.36  ? 185 ASP C O   1 
ATOM   8191 C CB  . ASP D 2 189 ? -51.63  10.93   31.071  1   43.13  ? 185 ASP C CB  1 
ATOM   8192 C CG  . ASP D 2 189 ? -50.517 10.088  31.685  1   44.1   ? 185 ASP C CG  1 
ATOM   8193 O OD1 . ASP D 2 189 ? -50.023 10.432  32.795  1   42.45  ? 185 ASP C OD1 1 
ATOM   8194 O OD2 . ASP D 2 189 ? -50.161 9.067   31.05   1   45.32  ? 185 ASP C OD2 1 
ATOM   8195 N N   . ILE D 2 190 ? -54.265 12.727  30.778  1   43.07  ? 186 ILE C N   1 
ATOM   8196 C CA  . ILE D 2 190 ? -55.015 13.738  30.046  1   43.86  ? 186 ILE C CA  1 
ATOM   8197 C C   . ILE D 2 190 ? -55.329 14.923  30.969  1   44.83  ? 186 ILE C C   1 
ATOM   8198 O O   . ILE D 2 190 ? -55.275 16.084  30.542  1   45.47  ? 186 ILE C O   1 
ATOM   8199 C CB  . ILE D 2 190 ? -56.282 13.155  29.367  1   44.75  ? 186 ILE C CB  1 
ATOM   8200 C CG1 . ILE D 2 190 ? -55.919 12.275  28.157  1   42.97  ? 186 ILE C CG1 1 
ATOM   8201 C CG2 . ILE D 2 190 ? -57.254 14.27   28.958  1   44.07  ? 186 ILE C CG2 1 
ATOM   8202 C CD1 . ILE D 2 190 ? -55.422 13.067  26.961  1   42.2   ? 186 ILE C CD1 1 
ATOM   8203 N N   . TRP D 2 191 ? -55.609 14.638  32.248  1   44.9   ? 187 TRP C N   1 
ATOM   8204 C CA  . TRP D 2 191 ? -55.901 15.702  33.194  1   46.29  ? 187 TRP C CA  1 
ATOM   8205 C C   . TRP D 2 191 ? -54.701 16.653  33.297  1   47.07  ? 187 TRP C C   1 
ATOM   8206 O O   . TRP D 2 191 ? -54.822 17.882  33.219  1   47.28  ? 187 TRP C O   1 
ATOM   8207 C CB  . TRP D 2 191 ? -56.291 15.083  34.547  1   47.34  ? 187 TRP C CB  1 
ATOM   8208 C CG  . TRP D 2 191 ? -56.612 16.123  35.584  1   48.97  ? 187 TRP C CG  1 
ATOM   8209 C CD1 . TRP D 2 191 ? -55.71  16.774  36.374  1   47.59  ? 187 TRP C CD1 1 
ATOM   8210 C CD2 . TRP D 2 191 ? -57.918 16.688  35.874  1   49.71  ? 187 TRP C CD2 1 
ATOM   8211 N NE1 . TRP D 2 191 ? -56.373 17.682  37.155  1   49.99  ? 187 TRP C NE1 1 
ATOM   8212 C CE2 . TRP D 2 191 ? -57.722 17.658  36.869  1   49.39  ? 187 TRP C CE2 1 
ATOM   8213 C CE3 . TRP D 2 191 ? -59.211 16.445  35.411  1   50.36  ? 187 TRP C CE3 1 
ATOM   8214 C CZ2 . TRP D 2 191 ? -58.775 18.38   37.411  1   50.78  ? 187 TRP C CZ2 1 
ATOM   8215 C CZ3 . TRP D 2 191 ? -60.256 17.146  35.955  1   52.48  ? 187 TRP C CZ3 1 
ATOM   8216 C CH2 . TRP D 2 191 ? -60.036 18.108  36.937  1   52.59  ? 187 TRP C CH2 1 
ATOM   8217 N N   . SER D 2 192 ? -53.515 16.059  33.438  1   45.72  ? 188 SER C N   1 
ATOM   8218 C CA  . SER D 2 192 ? -52.299 16.827  33.548  1   44.22  ? 188 SER C CA  1 
ATOM   8219 C C   . SER D 2 192 ? -52.143 17.718  32.319  1   45.45  ? 188 SER C C   1 
ATOM   8220 O O   . SER D 2 192 ? -51.857 18.91   32.435  1   46.99  ? 188 SER C O   1 
ATOM   8221 C CB  . SER D 2 192 ? -51.13  15.895  33.722  1   45.29  ? 188 SER C CB  1 
ATOM   8222 O OG  . SER D 2 192 ? -51.311 14.991  34.805  1   47.7   ? 188 SER C OG  1 
ATOM   8223 N N   . LEU D 2 193 ? -52.308 17.142  31.123  1   45.62  ? 189 LEU C N   1 
ATOM   8224 C CA  . LEU D 2 193 ? -52.167 17.923  29.906  1   45.52  ? 189 LEU C CA  1 
ATOM   8225 C C   . LEU D 2 193 ? -53.214 19.038  29.876  1   47.59  ? 189 LEU C C   1 
ATOM   8226 O O   . LEU D 2 193 ? -52.95  20.133  29.36   1   46.41  ? 189 LEU C O   1 
ATOM   8227 C CB  . LEU D 2 193 ? -52.254 17.045  28.665  1   46.2   ? 189 LEU C CB  1 
ATOM   8228 C CG  . LEU D 2 193 ? -50.995 16.268  28.282  1   47.34  ? 189 LEU C CG  1 
ATOM   8229 C CD1 . LEU D 2 193 ? -51.13  15.776  26.863  1   47.86  ? 189 LEU C CD1 1 
ATOM   8230 C CD2 . LEU D 2 193 ? -49.738 17.1    28.406  1   49.86  ? 189 LEU C CD2 1 
ATOM   8231 N N   . GLY D 2 194 ? -54.419 18.765  30.417  1   46.8   ? 190 GLY C N   1 
ATOM   8232 C CA  . GLY D 2 194 ? -55.412 19.818  30.479  1   45.59  ? 190 GLY C CA  1 
ATOM   8233 C C   . GLY D 2 194 ? -54.882 20.994  31.289  1   46.79  ? 190 GLY C C   1 
ATOM   8234 O O   . GLY D 2 194 ? -54.885 22.141  30.831  1   47.53  ? 190 GLY C O   1 
ATOM   8235 N N   . CYS D 2 195 ? -54.391 20.667  32.483  1   47.21  ? 191 CYS C N   1 
ATOM   8236 C CA  . CYS D 2 195 ? -53.754 21.618  33.374  1   49.15  ? 191 CYS C CA  1 
ATOM   8237 C C   . CYS D 2 195 ? -52.631 22.354  32.644  1   50.75  ? 191 CYS C C   1 
ATOM   8238 O O   . CYS D 2 195 ? -52.469 23.569  32.774  1   52.77  ? 191 CYS C O   1 
ATOM   8239 C CB  . CYS D 2 195 ? -53.244 20.893  34.616  1   50.04  ? 191 CYS C CB  1 
ATOM   8240 S SG  . CYS D 2 195 ? -54.587 20.224  35.647  1   54.74  ? 191 CYS C SG  1 
ATOM   8241 N N   . ILE D 2 196 ? -51.85  21.61   31.861  1   49.67  ? 192 ILE C N   1 
ATOM   8242 C CA  . ILE D 2 196 ? -50.738 22.204  31.143  1   48.64  ? 192 ILE C CA  1 
ATOM   8243 C C   . ILE D 2 196 ? -51.258 23.129  30.035  1   50.15  ? 192 ILE C C   1 
ATOM   8244 O O   . ILE D 2 196 ? -50.764 24.253  29.899  1   52.69  ? 192 ILE C O   1 
ATOM   8245 C CB  . ILE D 2 196 ? -49.772 21.102  30.672  1   47.22  ? 192 ILE C CB  1 
ATOM   8246 C CG1 . ILE D 2 196 ? -48.972 20.611  31.869  1   47.35  ? 192 ILE C CG1 1 
ATOM   8247 C CG2 . ILE D 2 196 ? -48.85  21.595  29.548  1   45.72  ? 192 ILE C CG2 1 
ATOM   8248 C CD1 . ILE D 2 196 ? -48.556 19.154  31.799  1   49.31  ? 192 ILE C CD1 1 
ATOM   8249 N N   . PHE D 2 197 ? -52.255 22.666  29.256  1   48.01  ? 193 PHE C N   1 
ATOM   8250 C CA  . PHE D 2 197 ? -52.895 23.5    28.25   1   46.85  ? 193 PHE C CA  1 
ATOM   8251 C C   . PHE D 2 197 ? -53.255 24.852  28.856  1   48.72  ? 193 PHE C C   1 
ATOM   8252 O O   . PHE D 2 197 ? -52.816 25.884  28.366  1   48.57  ? 193 PHE C O   1 
ATOM   8253 C CB  . PHE D 2 197 ? -54.156 22.798  27.744  1   47.63  ? 193 PHE C CB  1 
ATOM   8254 C CG  . PHE D 2 197 ? -54.896 23.463  26.598  1   46.99  ? 193 PHE C CG  1 
ATOM   8255 C CD1 . PHE D 2 197 ? -54.317 24.497  25.863  1   46.9   ? 193 PHE C CD1 1 
ATOM   8256 C CD2 . PHE D 2 197 ? -56.171 23.025  26.257  1   47.82  ? 193 PHE C CD2 1 
ATOM   8257 C CE1 . PHE D 2 197 ? -55.003 25.08   24.804  1   48.39  ? 193 PHE C CE1 1 
ATOM   8258 C CE2 . PHE D 2 197 ? -56.842 23.595  25.183  1   48.66  ? 193 PHE C CE2 1 
ATOM   8259 C CZ  . PHE D 2 197 ? -56.265 24.631  24.469  1   49.31  ? 193 PHE C CZ  1 
ATOM   8260 N N   . ALA D 2 198 ? -54.029 24.836  29.951  1   50.22  ? 194 ALA C N   1 
ATOM   8261 C CA  . ALA D 2 198 ? -54.451 26.07   30.594  1   52.36  ? 194 ALA C CA  1 
ATOM   8262 C C   . ALA D 2 198 ? -53.245 26.912  31.002  1   52.68  ? 194 ALA C C   1 
ATOM   8263 O O   . ALA D 2 198 ? -53.263 28.13   30.836  1   55.13  ? 194 ALA C O   1 
ATOM   8264 C CB  . ALA D 2 198 ? -55.321 25.761  31.781  1   52.85  ? 194 ALA C CB  1 
ATOM   8265 N N   . GLU D 2 199 ? -52.224 26.255  31.555  1   50.96  ? 195 GLU C N   1 
ATOM   8266 C CA  . GLU D 2 199 ? -51.041 26.933  32.056  1   51.97  ? 195 GLU C CA  1 
ATOM   8267 C C   . GLU D 2 199 ? -50.28  27.598  30.899  1   54.03  ? 195 GLU C C   1 
ATOM   8268 O O   . GLU D 2 199 ? -49.713 28.671  31.081  1   54.79  ? 195 GLU C O   1 
ATOM   8269 C CB  . GLU D 2 199 ? -50.212 25.942  32.879  1   49.83  ? 195 GLU C CB  1 
ATOM   8270 C CG  . GLU D 2 199 ? -49.049 26.581  33.624  1   49.85  ? 195 GLU C CG  1 
ATOM   8271 C CD  . GLU D 2 199 ? -48.301 25.716  34.616  1   51.3   ? 195 GLU C CD  1 
ATOM   8272 O OE1 . GLU D 2 199 ? -48.806 24.589  34.889  1   49.22  ? 195 GLU C OE1 1 
ATOM   8273 O OE2 . GLU D 2 199 ? -47.192 26.16   35.091  1   54.1   ? 195 GLU C OE2 1 
ATOM   8274 N N   . MET D 2 200 ? -50.27  26.98   29.703  1   54.2   ? 196 MET C N   1 
ATOM   8275 C CA  . MET D 2 200 ? -49.578 27.567  28.559  1   53.08  ? 196 MET C CA  1 
ATOM   8276 C C   . MET D 2 200 ? -50.293 28.837  28.118  1   55.6   ? 196 MET C C   1 
ATOM   8277 O O   . MET D 2 200 ? -49.648 29.765  27.643  1   59.09  ? 196 MET C O   1 
ATOM   8278 C CB  . MET D 2 200 ? -49.501 26.613  27.367  1   50.71  ? 196 MET C CB  1 
ATOM   8279 C CG  . MET D 2 200 ? -48.427 25.565  27.511  1   49.62  ? 196 MET C CG  1 
ATOM   8280 S SD  . MET D 2 200 ? -48.187 24.679  25.961  1   51.55  ? 196 MET C SD  1 
ATOM   8281 C CE  . MET D 2 200 ? -49.638 23.63   25.839  1   47.93  ? 196 MET C CE  1 
ATOM   8282 N N   . VAL D 2 201 ? -51.613 28.886  28.318  1   54.62  ? 197 VAL C N   1 
ATOM   8283 C CA  . VAL D 2 201 ? -52.408 30.014  27.873  1   56.11  ? 197 VAL C CA  1 
ATOM   8284 C C   . VAL D 2 201 ? -52.244 31.188  28.831  1   57.8   ? 197 VAL C C   1 
ATOM   8285 O O   . VAL D 2 201 ? -52.217 32.312  28.36   1   61.94  ? 197 VAL C O   1 
ATOM   8286 C CB  . VAL D 2 201 ? -53.883 29.63   27.683  1   55.71  ? 197 VAL C CB  1 
ATOM   8287 C CG1 . VAL D 2 201 ? -54.756 30.848  27.432  1   59.53  ? 197 VAL C CG1 1 
ATOM   8288 C CG2 . VAL D 2 201 ? -54.057 28.628  26.555  1   53.71  ? 197 VAL C CG2 1 
ATOM   8289 N N   . THR D 2 202 ? -52.17  30.936  30.152  1   58.48  ? 198 THR C N   1 
ATOM   8290 C CA  . THR D 2 202 ? -52.148 31.979  31.177  1   58.05  ? 198 THR C CA  1 
ATOM   8291 C C   . THR D 2 202 ? -50.758 32.138  31.784  1   58     ? 198 THR C C   1 
ATOM   8292 O O   . THR D 2 202 ? -50.513 33.116  32.486  1   57.33  ? 198 THR C O   1 
ATOM   8293 C CB  . THR D 2 202 ? -53.141 31.712  32.31   1   57.45  ? 198 THR C CB  1 
ATOM   8294 O OG1 . THR D 2 202 ? -52.606 30.609  33.028  1   56.93  ? 198 THR C OG1 1 
ATOM   8295 C CG2 . THR D 2 202 ? -54.56  31.43   31.855  1   57.02  ? 198 THR C CG2 1 
ATOM   8296 N N   . ARG D 2 203 ? -49.909 31.112  31.613  1   60.66  ? 199 ARG C N   1 
ATOM   8297 C CA  . ARG D 2 203 ? -48.596 31.029  32.247  1   64.14  ? 199 ARG C CA  1 
ATOM   8298 C C   . ARG D 2 203 ? -48.677 31.069  33.779  1   66.35  ? 199 ARG C C   1 
ATOM   8299 O O   . ARG D 2 203 ? -47.698 31.389  34.445  1   70.47  ? 199 ARG C O   1 
ATOM   8300 C CB  . ARG D 2 203 ? -47.683 32.122  31.681  1   68.89  ? 199 ARG C CB  1 
ATOM   8301 C CG  . ARG D 2 203 ? -47.183 31.854  30.269  1   68.61  ? 199 ARG C CG  1 
ATOM   8302 C CD  . ARG D 2 203 ? -46.881 33.148  29.558  1   75.43  ? 199 ARG C CD  1 
ATOM   8303 N NE  . ARG D 2 203 ? -48.133 33.866  29.287  1   82.79  ? 199 ARG C NE  1 
ATOM   8304 C CZ  . ARG D 2 203 ? -48.369 35.149  29.546  1   85.28  ? 199 ARG C CZ  1 
ATOM   8305 N NH1 . ARG D 2 203 ? -47.393 35.961  29.944  1   81.53  ? 199 ARG C NH1 1 
ATOM   8306 N NH2 . ARG D 2 203 ? -49.6   35.596  29.393  1   84.01  ? 199 ARG C NH2 1 
ATOM   8307 N N   . ARG D 2 204 ? -49.85  30.761  34.342  1   66.33  ? 200 ARG C N   1 
ATOM   8308 C CA  . ARG D 2 204 ? -50.006 30.474  35.758  1   64.8   ? 200 ARG C CA  1 
ATOM   8309 C C   . ARG D 2 204 ? -50.607 29.075  35.853  1   63.56  ? 200 ARG C C   1 
ATOM   8310 O O   . ARG D 2 204 ? -51.438 28.71   35.019  1   66.71  ? 200 ARG C O   1 
ATOM   8311 C CB  . ARG D 2 204 ? -50.992 31.436  36.431  1   66.14  ? 200 ARG C CB  1 
ATOM   8312 C CG  . ARG D 2 204 ? -50.828 32.896  36.045  1   71.54  ? 200 ARG C CG  1 
ATOM   8313 C CD  . ARG D 2 204 ? -51.588 33.8    37.016  1   75.68  ? 200 ARG C CD  1 
ATOM   8314 N NE  . ARG D 2 204 ? -51.473 35.247  36.774  1   75.1   ? 200 ARG C NE  1 
ATOM   8315 C CZ  . ARG D 2 204 ? -51.897 35.903  35.689  1   75.69  ? 200 ARG C CZ  1 
ATOM   8316 N NH1 . ARG D 2 204 ? -52.443 35.239  34.691  1   76.26  ? 200 ARG C NH1 1 
ATOM   8317 N NH2 . ARG D 2 204 ? -51.779 37.217  35.595  1   74.87  ? 200 ARG C NH2 1 
ATOM   8318 N N   . ALA D 2 205 ? -50.212 28.308  36.875  1   58.16  ? 201 ALA C N   1 
ATOM   8319 C CA  . ALA D 2 205 ? -50.8   27      37.109  1   53.27  ? 201 ALA C CA  1 
ATOM   8320 C C   . ALA D 2 205 ? -52.299 27.166  37.331  1   54.1   ? 201 ALA C C   1 
ATOM   8321 O O   . ALA D 2 205 ? -52.724 28.146  37.934  1   53.94  ? 201 ALA C O   1 
ATOM   8322 C CB  . ALA D 2 205 ? -50.139 26.323  38.28   1   51.36  ? 201 ALA C CB  1 
ATOM   8323 N N   . LEU D 2 206 ? -53.08  26.223  36.791  1   52.66  ? 202 LEU C N   1 
ATOM   8324 C CA  . LEU D 2 206 ? -54.526 26.275  36.874  1   51.63  ? 202 LEU C CA  1 
ATOM   8325 C C   . LEU D 2 206 ? -54.968 26      38.311  1   52.61  ? 202 LEU C C   1 
ATOM   8326 O O   . LEU D 2 206 ? -55.758 26.75   38.855  1   54.19  ? 202 LEU C O   1 
ATOM   8327 C CB  . LEU D 2 206 ? -55.079 25.24   35.897  1   50.23  ? 202 LEU C CB  1 
ATOM   8328 C CG  . LEU D 2 206 ? -56.606 25.183  35.773  1   50.71  ? 202 LEU C CG  1 
ATOM   8329 C CD1 . LEU D 2 206 ? -57.193 26.524  35.244  1   50.18  ? 202 LEU C CD1 1 
ATOM   8330 C CD2 . LEU D 2 206 ? -57     23.97   34.915  1   48.48  ? 202 LEU C CD2 1 
ATOM   8331 N N   . PHE D 2 207 ? -54.431 24.944  38.932  1   52.74  ? 203 PHE C N   1 
ATOM   8332 C CA  . PHE D 2 207 ? -54.884 24.498  40.249  1   54.16  ? 203 PHE C CA  1 
ATOM   8333 C C   . PHE D 2 207 ? -53.687 24.416  41.206  1   54.08  ? 203 PHE C C   1 
ATOM   8334 O O   . PHE D 2 207 ? -53.188 23.321  41.5    1   53.75  ? 203 PHE C O   1 
ATOM   8335 C CB  . PHE D 2 207 ? -55.56  23.127  40.075  1   53.2   ? 203 PHE C CB  1 
ATOM   8336 C CG  . PHE D 2 207 ? -56.777 23.105  39.158  1   52.56  ? 203 PHE C CG  1 
ATOM   8337 C CD1 . PHE D 2 207 ? -57.803 24.029  39.307  1   51.95  ? 203 PHE C CD1 1 
ATOM   8338 C CD2 . PHE D 2 207 ? -56.899 22.138  38.162  1   51.69  ? 203 PHE C CD2 1 
ATOM   8339 C CE1 . PHE D 2 207 ? -58.919 23.992  38.484  1   52.77  ? 203 PHE C CE1 1 
ATOM   8340 C CE2 . PHE D 2 207 ? -58.035 22.092  37.356  1   52.16  ? 203 PHE C CE2 1 
ATOM   8341 C CZ  . PHE D 2 207 ? -59.047 23.023  37.517  1   52.45  ? 203 PHE C CZ  1 
ATOM   8342 N N   . PRO D 2 208 ? -53.159 25.569  41.681  1   53.61  ? 204 PRO C N   1 
ATOM   8343 C CA  . PRO D 2 208 ? -51.96  25.592  42.527  1   53.86  ? 204 PRO C CA  1 
ATOM   8344 C C   . PRO D 2 208 ? -52.254 25.355  44.003  1   55.35  ? 204 PRO C C   1 
ATOM   8345 O O   . PRO D 2 208 ? -52.288 26.307  44.775  1   60.73  ? 204 PRO C O   1 
ATOM   8346 C CB  . PRO D 2 208 ? -51.443 27.033  42.3    1   52.49  ? 204 PRO C CB  1 
ATOM   8347 C CG  . PRO D 2 208 ? -52.704 27.842  42.159  1   53.18  ? 204 PRO C CG  1 
ATOM   8348 C CD  . PRO D 2 208 ? -53.666 26.923  41.398  1   53.57  ? 204 PRO C CD  1 
ATOM   8349 N N   . GLY D 2 209 ? -52.44  24.1    44.398  1   54.58  ? 205 GLY C N   1 
ATOM   8350 C CA  . GLY D 2 209 ? -52.856 23.807  45.76   1   56.99  ? 205 GLY C CA  1 
ATOM   8351 C C   . GLY D 2 209 ? -51.703 23.748  46.769  1   57.68  ? 205 GLY C C   1 
ATOM   8352 O O   . GLY D 2 209 ? -50.578 23.439  46.421  1   56.38  ? 205 GLY C O   1 
ATOM   8353 N N   . ASP D 2 210 ? -52.026 24.006  48.04   1   61.17  ? 206 ASP C N   1 
ATOM   8354 C CA  . ASP D 2 210 ? -51.096 23.898  49.152  1   65.83  ? 206 ASP C CA  1 
ATOM   8355 C C   . ASP D 2 210 ? -51.2   22.537  49.847  1   66.37  ? 206 ASP C C   1 
ATOM   8356 O O   . ASP D 2 210 ? -50.359 22.214  50.68   1   67.16  ? 206 ASP C O   1 
ATOM   8357 C CB  . ASP D 2 210 ? -51.35  25.014  50.15   1   70.37  ? 206 ASP C CB  1 
ATOM   8358 C CG  . ASP D 2 210 ? -51.467 26.395  49.521  1   76.28  ? 206 ASP C CG  1 
ATOM   8359 O OD1 . ASP D 2 210 ? -50.641 26.673  48.609  1   75.28  ? 206 ASP C OD1 1 
ATOM   8360 O OD2 . ASP D 2 210 ? -52.383 27.164  49.936  1   78.62  ? 206 ASP C OD2 1 
ATOM   8361 N N   . SER D 2 211 ? -52.24  21.754  49.53   1   67.36  ? 207 SER C N   1 
ATOM   8362 C CA  . SER D 2 211 ? -52.57  20.49   50.184  1   67.01  ? 207 SER C CA  1 
ATOM   8363 C C   . SER D 2 211 ? -53.597 19.73   49.34   1   67.8   ? 207 SER C C   1 
ATOM   8364 O O   . SER D 2 211 ? -54.178 20.301  48.411  1   67.9   ? 207 SER C O   1 
ATOM   8365 C CB  . SER D 2 211 ? -53.099 20.73   51.588  1   67.64  ? 207 SER C CB  1 
ATOM   8366 O OG  . SER D 2 211 ? -54.383 21.346  51.56   1   67.89  ? 207 SER C OG  1 
ATOM   8367 N N   . GLU D 2 212 ? -53.847 18.454  49.682  1   67.78  ? 208 GLU C N   1 
ATOM   8368 C CA  . GLU D 2 212 ? -54.826 17.652  48.953  1   68.57  ? 208 GLU C CA  1 
ATOM   8369 C C   . GLU D 2 212 ? -56.232 18.251  49.066  1   66.43  ? 208 GLU C C   1 
ATOM   8370 O O   . GLU D 2 212 ? -56.965 18.348  48.077  1   63.62  ? 208 GLU C O   1 
ATOM   8371 C CB  . GLU D 2 212 ? -54.786 16.196  49.41   1   73.49  ? 208 GLU C CB  1 
ATOM   8372 C CG  . GLU D 2 212 ? -53.408 15.578  49.207  1   79.69  ? 208 GLU C CG  1 
ATOM   8373 C CD  . GLU D 2 212 ? -53.204 14.17   49.72   1   83.13  ? 208 GLU C CD  1 
ATOM   8374 O OE1 . GLU D 2 212 ? -54.152 13.552  50.221  1   85.4   ? 208 GLU C OE1 1 
ATOM   8375 O OE2 . GLU D 2 212 ? -52.062 13.701  49.605  1   84.66  ? 208 GLU C OE2 1 
ATOM   8376 N N   . ILE D 2 213 ? -56.616 18.66   50.279  1   66.78  ? 209 ILE C N   1 
ATOM   8377 C CA  . ILE D 2 213 ? -57.948 19.219  50.466  1   68.16  ? 209 ILE C CA  1 
ATOM   8378 C C   . ILE D 2 213 ? -58.033 20.546  49.708  1   67.47  ? 209 ILE C C   1 
ATOM   8379 O O   . ILE D 2 213 ? -59.057 20.826  49.08   1   67.72  ? 209 ILE C O   1 
ATOM   8380 C CB  . ILE D 2 213 ? -58.353 19.341  51.948  1   68.87  ? 209 ILE C CB  1 
ATOM   8381 C CG1 . ILE D 2 213 ? -59.805 19.772  52.093  1   74.14  ? 209 ILE C CG1 1 
ATOM   8382 C CG2 . ILE D 2 213 ? -57.424 20.272  52.724  1   68.34  ? 209 ILE C CG2 1 
ATOM   8383 C CD1 . ILE D 2 213 ? -60.8   18.623  52.202  1   78.93  ? 209 ILE C CD1 1 
ATOM   8384 N N   . ASP D 2 214 ? -56.933 21.318  49.712  1   63.9   ? 210 ASP C N   1 
ATOM   8385 C CA  . ASP D 2 214 ? -56.893 22.598  49.017  1   62.55  ? 210 ASP C CA  1 
ATOM   8386 C C   . ASP D 2 214 ? -56.959 22.406  47.498  1   59.93  ? 210 ASP C C   1 
ATOM   8387 O O   . ASP D 2 214 ? -57.573 23.208  46.786  1   57.08  ? 210 ASP C O   1 
ATOM   8388 C CB  . ASP D 2 214 ? -55.713 23.439  49.466  1   62.41  ? 210 ASP C CB  1 
ATOM   8389 C CG  . ASP D 2 214 ? -55.603 24.792  48.782  1   62.27  ? 210 ASP C CG  1 
ATOM   8390 O OD1 . ASP D 2 214 ? -56.543 25.588  48.913  1   63.77  ? 210 ASP C OD1 1 
ATOM   8391 O OD2 . ASP D 2 214 ? -54.576 25.034  48.112  1   62.24  ? 210 ASP C OD2 1 
ATOM   8392 N N   . GLN D 2 215 ? -56.316 21.326  47.027  1   60.47  ? 211 GLN C N   1 
ATOM   8393 C CA  . GLN D 2 215 ? -56.304 20.918  45.633  1   59.02  ? 211 GLN C CA  1 
ATOM   8394 C C   . GLN D 2 215 ? -57.729 20.693  45.13   1   61.09  ? 211 GLN C C   1 
ATOM   8395 O O   . GLN D 2 215 ? -58.089 21.209  44.069  1   62.8   ? 211 GLN C O   1 
ATOM   8396 C CB  . GLN D 2 215 ? -55.435 19.674  45.488  1   59.23  ? 211 GLN C CB  1 
ATOM   8397 C CG  . GLN D 2 215 ? -55.028 19.333  44.054  1   60.15  ? 211 GLN C CG  1 
ATOM   8398 C CD  . GLN D 2 215 ? -54.253 20.435  43.364  1   61.39  ? 211 GLN C CD  1 
ATOM   8399 O OE1 . GLN D 2 215 ? -53.472 21.156  43.998  1   62.21  ? 211 GLN C OE1 1 
ATOM   8400 N NE2 . GLN D 2 215 ? -54.506 20.618  42.075  1   59.99  ? 211 GLN C NE2 1 
ATOM   8401 N N   . LEU D 2 216 ? -58.545 19.949  45.899  1   61.67  ? 212 LEU C N   1 
ATOM   8402 C CA  . LEU D 2 216 ? -59.913 19.628  45.499  1   61.35  ? 212 LEU C CA  1 
ATOM   8403 C C   . LEU D 2 216 ? -60.778 20.887  45.459  1   63.18  ? 212 LEU C C   1 
ATOM   8404 O O   . LEU D 2 216 ? -61.6   21.099  44.559  1   63.1   ? 212 LEU C O   1 
ATOM   8405 C CB  . LEU D 2 216 ? -60.481 18.633  46.504  1   61.98  ? 212 LEU C CB  1 
ATOM   8406 C CG  . LEU D 2 216 ? -59.941 17.212  46.382  1   62.14  ? 212 LEU C CG  1 
ATOM   8407 C CD1 . LEU D 2 216 ? -60.281 16.398  47.607  1   63.34  ? 212 LEU C CD1 1 
ATOM   8408 C CD2 . LEU D 2 216 ? -60.472 16.557  45.108  1   62.42  ? 212 LEU C CD2 1 
ATOM   8409 N N   . PHE D 2 217 ? -60.595 21.719  46.483  1   63.29  ? 213 PHE C N   1 
ATOM   8410 C CA  . PHE D 2 217 ? -61.326 22.965  46.562  1   64.33  ? 213 PHE C CA  1 
ATOM   8411 C C   . PHE D 2 217 ? -61.042 23.797  45.314  1   64.08  ? 213 PHE C C   1 
ATOM   8412 O O   . PHE D 2 217 ? -61.97  24.36   44.743  1   66.41  ? 213 PHE C O   1 
ATOM   8413 C CB  . PHE D 2 217 ? -61.005 23.639  47.9    1   66.7   ? 213 PHE C CB  1 
ATOM   8414 C CG  . PHE D 2 217 ? -61.571 22.994  49.164  1   67.86  ? 213 PHE C CG  1 
ATOM   8415 C CD1 . PHE D 2 217 ? -62.151 21.728  49.144  1   68.04  ? 213 PHE C CD1 1 
ATOM   8416 C CD2 . PHE D 2 217 ? -61.482 23.651  50.384  1   69.12  ? 213 PHE C CD2 1 
ATOM   8417 C CE1 . PHE D 2 217 ? -62.629 21.155  50.307  1   69.57  ? 213 PHE C CE1 1 
ATOM   8418 C CE2 . PHE D 2 217 ? -61.956 23.066  51.548  1   70.64  ? 213 PHE C CE2 1 
ATOM   8419 C CZ  . PHE D 2 217 ? -62.534 21.824  51.51   1   71.43  ? 213 PHE C CZ  1 
ATOM   8420 N N   . ARG D 2 218 ? -59.776 23.84   44.864  1   61.84  ? 214 ARG C N   1 
ATOM   8421 C CA  . ARG D 2 218 ? -59.398 24.643  43.705  1   61.04  ? 214 ARG C CA  1 
ATOM   8422 C C   . ARG D 2 218 ? -60.078 24.122  42.44   1   58.79  ? 214 ARG C C   1 
ATOM   8423 O O   . ARG D 2 218 ? -60.555 24.902  41.61   1   58.29  ? 214 ARG C O   1 
ATOM   8424 C CB  . ARG D 2 218 ? -57.873 24.702  43.533  1   61.16  ? 214 ARG C CB  1 
ATOM   8425 C CG  . ARG D 2 218 ? -57.257 25.751  44.449  1   64.03  ? 214 ARG C CG  1 
ATOM   8426 C CD  . ARG D 2 218 ? -55.739 25.655  44.517  1   62.69  ? 214 ARG C CD  1 
ATOM   8427 N NE  . ARG D 2 218 ? -55.265 26.438  45.663  1   63.55  ? 214 ARG C NE  1 
ATOM   8428 C CZ  . ARG D 2 218 ? -55.155 27.755  45.675  1   64.1   ? 214 ARG C CZ  1 
ATOM   8429 N NH1 . ARG D 2 218 ? -55.334 28.447  44.559  1   64.57  ? 214 ARG C NH1 1 
ATOM   8430 N NH2 . ARG D 2 218 ? -54.802 28.353  46.792  1   63.99  ? 214 ARG C NH2 1 
ATOM   8431 N N   . ILE D 2 219 ? -60.098 22.797  42.306  1   56.64  ? 215 ILE C N   1 
ATOM   8432 C CA  . ILE D 2 219 ? -60.727 22.168  41.156  1   57.61  ? 215 ILE C CA  1 
ATOM   8433 C C   . ILE D 2 219 ? -62.248 22.441  41.169  1   60.77  ? 215 ILE C C   1 
ATOM   8434 O O   . ILE D 2 219 ? -62.814 22.932  40.177  1   58.78  ? 215 ILE C O   1 
ATOM   8435 C CB  . ILE D 2 219 ? -60.343 20.68   41.141  1   53.71  ? 215 ILE C CB  1 
ATOM   8436 C CG1 . ILE D 2 219 ? -58.82  20.53   40.891  1   50.44  ? 215 ILE C CG1 1 
ATOM   8437 C CG2 . ILE D 2 219 ? -61.201 19.918  40.129  1   52.58  ? 215 ILE C CG2 1 
ATOM   8438 C CD1 . ILE D 2 219 ? -58.241 19.179  41.262  1   48.65  ? 215 ILE C CD1 1 
ATOM   8439 N N   . PHE D 2 220 ? -62.907 22.152  42.29   1   62.33  ? 216 PHE C N   1 
ATOM   8440 C CA  . PHE D 2 220 ? -64.385 22.31   42.384  1   65.26  ? 216 PHE C CA  1 
ATOM   8441 C C   . PHE D 2 220 ? -64.794 23.748  42.116  1   68.33  ? 216 PHE C C   1 
ATOM   8442 O O   . PHE D 2 220 ? -65.7   23.982  41.311  1   72.9   ? 216 PHE C O   1 
ATOM   8443 C CB  . PHE D 2 220 ? -64.84  21.876  43.777  1   63.62  ? 216 PHE C CB  1 
ATOM   8444 C CG  . PHE D 2 220 ? -64.6   20.419  44.141  1   62.63  ? 216 PHE C CG  1 
ATOM   8445 C CD1 . PHE D 2 220 ? -64.191 19.496  43.187  1   60.12  ? 216 PHE C CD1 1 
ATOM   8446 C CD2 . PHE D 2 220 ? -64.783 19.98   45.444  1   63.53  ? 216 PHE C CD2 1 
ATOM   8447 C CE1 . PHE D 2 220 ? -63.97  18.176  43.531  1   59.81  ? 216 PHE C CE1 1 
ATOM   8448 C CE2 . PHE D 2 220 ? -64.562 18.656  45.78   1   63.96  ? 216 PHE C CE2 1 
ATOM   8449 C CZ  . PHE D 2 220 ? -64.159 17.758  44.824  1   62.06  ? 216 PHE C CZ  1 
ATOM   8450 N N   . ARG D 2 221 ? -64.133 24.695  42.765  1   68.63  ? 217 ARG C N   1 
ATOM   8451 C CA  . ARG D 2 221 ? -64.499 26.127  42.634  1   70.61  ? 217 ARG C CA  1 
ATOM   8452 C C   . ARG D 2 221 ? -64.426 26.618  41.184  1   71.06  ? 217 ARG C C   1 
ATOM   8453 O O   . ARG D 2 221 ? -64.988 27.693  40.907  1   72.44  ? 217 ARG C O   1 
ATOM   8454 C CB  . ARG D 2 221 ? -63.512 26.927  43.488  1   69.81  ? 217 ARG C CB  1 
ATOM   8455 C CG  . ARG D 2 221 ? -64.138 27.95   44.42   1   66.46  ? 217 ARG C CG  1 
ATOM   8456 C CD  . ARG D 2 221 ? -63.168 29.051  44.787  1   65.42  ? 217 ARG C CD  1 
ATOM   8457 N NE  . ARG D 2 221 ? -62.731 29.795  43.602  1   65.64  ? 217 ARG C NE  1 
ATOM   8458 C CZ  . ARG D 2 221 ? -63.373 30.828  43.074  1   65.12  ? 217 ARG C CZ  1 
ATOM   8459 N NH1 . ARG D 2 221 ? -64.513 31.236  43.597  1   66.52  ? 217 ARG C NH1 1 
ATOM   8460 N NH2 . ARG D 2 221 ? -62.869 31.451  42.024  1   63.36  ? 217 ARG C NH2 1 
ATOM   8461 N N   . THR D 2 222 ? -63.774 25.876  40.291  1   69.71  ? 218 THR C N   1 
ATOM   8462 C CA  . THR D 2 222 ? -63.561 26.387  38.923  1   70.11  ? 218 THR C CA  1 
ATOM   8463 C C   . THR D 2 222 ? -64.381 25.57   37.955  1   71.08  ? 218 THR C C   1 
ATOM   8464 O O   . THR D 2 222 ? -64.872 26.148  36.967  1   71.15  ? 218 THR C O   1 
ATOM   8465 C CB  . THR D 2 222 ? -62.064 26.347  38.614  1   69.53  ? 218 THR C CB  1 
ATOM   8466 O OG1 . THR D 2 222 ? -61.479 27.39   39.386  1   66.43  ? 218 THR C OG1 1 
ATOM   8467 C CG2 . THR D 2 222 ? -61.751 26.563  37.145  1   67.33  ? 218 THR C CG2 1 
ATOM   8468 N N   . LEU D 2 223 ? -64.589 24.286  38.249  1   69.66  ? 219 LEU C N   1 
ATOM   8469 C CA  . LEU D 2 223 ? -65.275 23.407  37.307  1   70.34  ? 219 LEU C CA  1 
ATOM   8470 C C   . LEU D 2 223 ? -66.688 23.072  37.776  1   75.32  ? 219 LEU C C   1 
ATOM   8471 O O   . LEU D 2 223 ? -67.367 22.269  37.14   1   78.4   ? 219 LEU C O   1 
ATOM   8472 C CB  . LEU D 2 223 ? -64.493 22.106  37.108  1   66.62  ? 219 LEU C CB  1 
ATOM   8473 C CG  . LEU D 2 223 ? -63.042 22.233  36.621  1   64.86  ? 219 LEU C CG  1 
ATOM   8474 C CD1 . LEU D 2 223 ? -62.397 20.866  36.527  1   61.14  ? 219 LEU C CD1 1 
ATOM   8475 C CD2 . LEU D 2 223 ? -62.921 22.947  35.273  1   65.27  ? 219 LEU C CD2 1 
ATOM   8476 N N   . GLY D 2 224 ? -67.106 23.635  38.915  1   77.63  ? 220 GLY C N   1 
ATOM   8477 C CA  . GLY D 2 224 ? -68.328 23.22   39.591  1   76.9   ? 220 GLY C CA  1 
ATOM   8478 C C   . GLY D 2 224 ? -68.062 21.999  40.472  1   75.93  ? 220 GLY C C   1 
ATOM   8479 O O   . GLY D 2 224 ? -67.317 21.098  40.086  1   70.01  ? 220 GLY C O   1 
ATOM   8480 N N   . THR D 2 225 ? -68.626 22.015  41.687  1   78.64  ? 221 THR C N   1 
ATOM   8481 C CA  . THR D 2 225 ? -68.589 20.854  42.566  1   83.82  ? 221 THR C CA  1 
ATOM   8482 C C   . THR D 2 225 ? -69.284 19.708  41.835  1   89.65  ? 221 THR C C   1 
ATOM   8483 O O   . THR D 2 225 ? -70.409 19.885  41.375  1   94.48  ? 221 THR C O   1 
ATOM   8484 C CB  . THR D 2 225 ? -69.287 21.161  43.894  1   83.93  ? 221 THR C CB  1 
ATOM   8485 O OG1 . THR D 2 225 ? -68.681 22.341  44.411  1   80.02  ? 221 THR C OG1 1 
ATOM   8486 C CG2 . THR D 2 225 ? -69.198 20.015  44.889  1   83.82  ? 221 THR C CG2 1 
ATOM   8487 N N   . PRO D 2 226 ? -68.659 18.514  41.69   1   94.09  ? 222 PRO C N   1 
ATOM   8488 C CA  . PRO D 2 226 ? -69.29  17.407  40.962  1   100.78 ? 222 PRO C CA  1 
ATOM   8489 C C   . PRO D 2 226 ? -70.381 16.753  41.806  1   106.76 ? 222 PRO C C   1 
ATOM   8490 O O   . PRO D 2 226 ? -70.351 16.838  43.038  1   106.87 ? 222 PRO C O   1 
ATOM   8491 C CB  . PRO D 2 226 ? -68.125 16.44   40.662  1   99.8   ? 222 PRO C CB  1 
ATOM   8492 C CG  . PRO D 2 226 ? -67.122 16.703  41.784  1   95.38  ? 222 PRO C CG  1 
ATOM   8493 C CD  . PRO D 2 226 ? -67.34  18.153  42.233  1   93.34  ? 222 PRO C CD  1 
ATOM   8494 N N   . ASP D 2 227 ? -71.341 16.125  41.116  1   108.87 ? 223 ASP C N   1 
ATOM   8495 C CA  . ASP D 2 227 ? -72.401 15.353  41.745  1   107.91 ? 223 ASP C CA  1 
ATOM   8496 C C   . ASP D 2 227 ? -72.589 14.066  40.94   1   107.58 ? 223 ASP C C   1 
ATOM   8497 O O   . ASP D 2 227 ? -71.87  13.823  39.969  1   99.35  ? 223 ASP C O   1 
ATOM   8498 C CB  . ASP D 2 227 ? -73.656 16.197  41.952  1   111.33 ? 223 ASP C CB  1 
ATOM   8499 C CG  . ASP D 2 227 ? -74.287 16.808  40.702  1   115.24 ? 223 ASP C CG  1 
ATOM   8500 O OD1 . ASP D 2 227 ? -73.816 16.515  39.575  1   121.93 ? 223 ASP C OD1 1 
ATOM   8501 O OD2 . ASP D 2 227 ? -75.236 17.599  40.859  1   115.39 ? 223 ASP C OD2 1 
ATOM   8502 N N   . GLU D 2 228 ? -73.575 13.253  41.341  1   109.16 ? 224 GLU C N   1 
ATOM   8503 C CA  . GLU D 2 228 ? -73.852 11.982  40.693  1   105.69 ? 224 GLU C CA  1 
ATOM   8504 C C   . GLU D 2 228 ? -74.298 12.209  39.245  1   107.4  ? 224 GLU C C   1 
ATOM   8505 O O   . GLU D 2 228 ? -74.154 11.31   38.419  1   110.33 ? 224 GLU C O   1 
ATOM   8506 C CB  . GLU D 2 228 ? -74.826 11.18   41.556  1   105.16 ? 224 GLU C CB  1 
ATOM   8507 C CG  . GLU D 2 228 ? -74.172 10.581  42.799  1   103.77 ? 224 GLU C CG  1 
ATOM   8508 C CD  . GLU D 2 228 ? -73.254 9.382   42.596  1   102.4  ? 224 GLU C CD  1 
ATOM   8509 O OE1 . GLU D 2 228 ? -73.272 8.793   41.506  1   103.96 ? 224 GLU C OE1 1 
ATOM   8510 O OE2 . GLU D 2 228 ? -72.524 9.02    43.531  1   98.24  ? 224 GLU C OE2 1 
ATOM   8511 N N   . VAL D 2 229 ? -74.798 13.414  38.939  1   104.26 ? 225 VAL C N   1 
ATOM   8512 C CA  . VAL D 2 229 ? -75.232 13.771  37.593  1   102.09 ? 225 VAL C CA  1 
ATOM   8513 C C   . VAL D 2 229 ? -74.014 13.941  36.674  1   96.18  ? 225 VAL C C   1 
ATOM   8514 O O   . VAL D 2 229 ? -73.96  13.34   35.6    1   89.38  ? 225 VAL C O   1 
ATOM   8515 C CB  . VAL D 2 229 ? -76.152 15.012  37.582  1   102.29 ? 225 VAL C CB  1 
ATOM   8516 C CG1 . VAL D 2 229 ? -76.695 15.343  36.192  1   98.07  ? 225 VAL C CG1 1 
ATOM   8517 C CG2 . VAL D 2 229 ? -77.292 14.879  38.587  1   104.95 ? 225 VAL C CG2 1 
ATOM   8518 N N   . VAL D 2 230 ? -73.042 14.76   37.095  1   95.87  ? 226 VAL C N   1 
ATOM   8519 C CA  . VAL D 2 230 ? -71.837 15.016  36.31   1   100.52 ? 226 VAL C CA  1 
ATOM   8520 C C   . VAL D 2 230 ? -70.926 13.781  36.328  1   97.01  ? 226 VAL C C   1 
ATOM   8521 O O   . VAL D 2 230 ? -70.473 13.317  35.283  1   92.01  ? 226 VAL C O   1 
ATOM   8522 C CB  . VAL D 2 230 ? -71.087 16.289  36.768  1   98.31  ? 226 VAL C CB  1 
ATOM   8523 C CG1 . VAL D 2 230 ? -69.751 16.438  36.056  1   89.73  ? 226 VAL C CG1 1 
ATOM   8524 C CG2 . VAL D 2 230 ? -71.938 17.549  36.588  1   97.46  ? 226 VAL C CG2 1 
ATOM   8525 N N   . TRP D 2 231 ? -70.67  13.264  37.535  1   97.63  ? 227 TRP C N   1 
ATOM   8526 C CA  . TRP D 2 231 ? -69.713 12.197  37.767  1   92.64  ? 227 TRP C CA  1 
ATOM   8527 C C   . TRP D 2 231 ? -70.366 11.081  38.589  1   95.21  ? 227 TRP C C   1 
ATOM   8528 O O   . TRP D 2 231 ? -70.271 11.065  39.815  1   94.15  ? 227 TRP C O   1 
ATOM   8529 C CB  . TRP D 2 231 ? -68.486 12.789  38.474  1   87.49  ? 227 TRP C CB  1 
ATOM   8530 C CG  . TRP D 2 231 ? -67.327 11.841  38.64   1   86.84  ? 227 TRP C CG  1 
ATOM   8531 C CD1 . TRP D 2 231 ? -67.25  10.55   38.21   1   83.98  ? 227 TRP C CD1 1 
ATOM   8532 C CD2 . TRP D 2 231 ? -66.054 12.144  39.256  1   86.31  ? 227 TRP C CD2 1 
ATOM   8533 N NE1 . TRP D 2 231 ? -66.035 10.021  38.536  1   82.03  ? 227 TRP C NE1 1 
ATOM   8534 C CE2 . TRP D 2 231 ? -65.276 10.971  39.173  1   85.89  ? 227 TRP C CE2 1 
ATOM   8535 C CE3 . TRP D 2 231 ? -65.496 13.279  39.867  1   87.93  ? 227 TRP C CE3 1 
ATOM   8536 C CZ2 . TRP D 2 231 ? -63.971 10.915  39.671  1   83.04  ? 227 TRP C CZ2 1 
ATOM   8537 C CZ3 . TRP D 2 231 ? -64.213 13.225  40.368  1   82.55  ? 227 TRP C CZ3 1 
ATOM   8538 C CH2 . TRP D 2 231 ? -63.464 12.049  40.271  1   83.27  ? 227 TRP C CH2 1 
ATOM   8539 N N   . PRO D 2 232 ? -71.066 10.116  37.951  1   97.77  ? 228 PRO C N   1 
ATOM   8540 C CA  . PRO D 2 232 ? -71.605 8.952   38.663  1   100.75 ? 228 PRO C CA  1 
ATOM   8541 C C   . PRO D 2 232 ? -70.57  8.176   39.481  1   96.57  ? 228 PRO C C   1 
ATOM   8542 O O   . PRO D 2 232 ? -69.527 7.785   38.965  1   90.64  ? 228 PRO C O   1 
ATOM   8543 C CB  . PRO D 2 232 ? -72.253 8.087   37.547  1   100.43 ? 228 PRO C CB  1 
ATOM   8544 C CG  . PRO D 2 232 ? -72.548 9.076   36.437  1   100.29 ? 228 PRO C CG  1 
ATOM   8545 C CD  . PRO D 2 232 ? -71.428 10.119  36.523  1   101.18 ? 228 PRO C CD  1 
ATOM   8546 N N   . GLY D 2 233 ? -70.877 7.971   40.767  1   97.1   ? 229 GLY C N   1 
ATOM   8547 C CA  . GLY D 2 233 ? -69.995 7.267   41.683  1   99.24  ? 229 GLY C CA  1 
ATOM   8548 C C   . GLY D 2 233 ? -69.041 8.193   42.443  1   99.41  ? 229 GLY C C   1 
ATOM   8549 O O   . GLY D 2 233 ? -68.263 7.712   43.267  1   102.85 ? 229 GLY C O   1 
ATOM   8550 N N   . VAL D 2 234 ? -69.111 9.509   42.184  1   95.39  ? 230 VAL C N   1 
ATOM   8551 C CA  . VAL D 2 234 ? -68.25  10.484  42.843  1   94.54  ? 230 VAL C CA  1 
ATOM   8552 C C   . VAL D 2 234 ? -68.527 10.534  44.351  1   100.33 ? 230 VAL C C   1 
ATOM   8553 O O   . VAL D 2 234 ? -67.585 10.643  45.144  1   100.69 ? 230 VAL C O   1 
ATOM   8554 C CB  . VAL D 2 234 ? -68.344 11.897  42.236  1   91.44  ? 230 VAL C CB  1 
ATOM   8555 C CG1 . VAL D 2 234 ? -69.721 12.524  42.443  1   91.37  ? 230 VAL C CG1 1 
ATOM   8556 C CG2 . VAL D 2 234 ? -67.242 12.822  42.75   1   85.51  ? 230 VAL C CG2 1 
ATOM   8557 N N   . THR D 2 235 ? -69.814 10.477  44.741  1   97.18  ? 231 THR C N   1 
ATOM   8558 C CA  . THR D 2 235 ? -70.19  10.639  46.139  1   97.09  ? 231 THR C CA  1 
ATOM   8559 C C   . THR D 2 235 ? -69.906 9.355   46.931  1   97.62  ? 231 THR C C   1 
ATOM   8560 O O   . THR D 2 235 ? -69.931 9.378   48.16   1   100.65 ? 231 THR C O   1 
ATOM   8561 C CB  . THR D 2 235 ? -71.633 11.145  46.294  1   97.59  ? 231 THR C CB  1 
ATOM   8562 O OG1 . THR D 2 235 ? -72.561 10.11   45.963  1   93.4   ? 231 THR C OG1 1 
ATOM   8563 C CG2 . THR D 2 235 ? -71.913 12.403  45.49   1   95.4   ? 231 THR C CG2 1 
ATOM   8564 N N   . SER D 2 236 ? -69.652 8.241   46.226  1   96.53  ? 232 SER C N   1 
ATOM   8565 C CA  . SER D 2 236 ? -69.301 6.961   46.835  1   97.94  ? 232 SER C CA  1 
ATOM   8566 C C   . SER D 2 236 ? -67.779 6.795   46.893  1   97.13  ? 232 SER C C   1 
ATOM   8567 O O   . SER D 2 236 ? -67.285 5.729   47.26   1   95.52  ? 232 SER C O   1 
ATOM   8568 C CB  . SER D 2 236 ? -69.928 5.785   46.094  1   97.54  ? 232 SER C CB  1 
ATOM   8569 O OG  . SER D 2 236 ? -71.303 5.996   45.805  1   102.1  ? 232 SER C OG  1 
ATOM   8570 N N   . MET D 2 237 ? -67.072 7.858   46.492  1   94.73  ? 233 MET C N   1 
ATOM   8571 C CA  . MET D 2 237 ? -65.591 7.825   46.411  1   91.65  ? 233 MET C CA  1 
ATOM   8572 C C   . MET D 2 237 ? -64.96  7.801   47.803  1   92.17  ? 233 MET C C   1 
ATOM   8573 O O   . MET D 2 237 ? -65.435 8.524   48.7    1   89.46  ? 233 MET C O   1 
ATOM   8574 C CB  . MET D 2 237 ? -65.084 9.087   45.717  1   91.84  ? 233 MET C CB  1 
ATOM   8575 C CG  . MET D 2 237 ? -64.123 8.825   44.594  1   97.68  ? 233 MET C CG  1 
ATOM   8576 S SD  . MET D 2 237 ? -64.889 7.772   43.35   1   102.34 ? 233 MET C SD  1 
ATOM   8577 C CE  . MET D 2 237 ? -65.166 9.022   42.092  1   95.34  ? 233 MET C CE  1 
ATOM   8578 N N   . PRO D 2 238 ? -63.881 7.022   47.996  1   91.6   ? 234 PRO C N   1 
ATOM   8579 C CA  . PRO D 2 238 ? -63.23  6.916   49.312  1   90.62  ? 234 PRO C CA  1 
ATOM   8580 C C   . PRO D 2 238 ? -63.068 8.17    50.181  1   91.21  ? 234 PRO C C   1 
ATOM   8581 O O   . PRO D 2 238 ? -63.362 8.148   51.379  1   87.61  ? 234 PRO C O   1 
ATOM   8582 C CB  . PRO D 2 238 ? -61.856 6.311   48.946  1   89.53  ? 234 PRO C CB  1 
ATOM   8583 C CG  . PRO D 2 238 ? -62.107 5.479   47.705  1   88.27  ? 234 PRO C CG  1 
ATOM   8584 C CD  . PRO D 2 238 ? -63.245 6.161   46.978  1   89.13  ? 234 PRO C CD  1 
ATOM   8585 N N   . ASP D 2 239 ? -62.573 9.258   49.571  1   91.39  ? 235 ASP C N   1 
ATOM   8586 C CA  . ASP D 2 239 ? -62.28  10.489  50.291  1   94.68  ? 235 ASP C CA  1 
ATOM   8587 C C   . ASP D 2 239 ? -63.269 11.604  49.951  1   100.71 ? 235 ASP C C   1 
ATOM   8588 O O   . ASP D 2 239 ? -63.052 12.744  50.366  1   107.29 ? 235 ASP C O   1 
ATOM   8589 C CB  . ASP D 2 239 ? -60.828 10.907  50.121  1   94.35  ? 235 ASP C CB  1 
ATOM   8590 C CG  . ASP D 2 239 ? -59.826 9.872   50.606  1   98.04  ? 235 ASP C CG  1 
ATOM   8591 O OD1 . ASP D 2 239 ? -60.094 9.26    51.667  1   104.89 ? 235 ASP C OD1 1 
ATOM   8592 O OD2 . ASP D 2 239 ? -58.805 9.669   49.915  1   92.54  ? 235 ASP C OD2 1 
ATOM   8593 N N   . TYR D 2 240 ? -64.35  11.288  49.214  1   98.98  ? 236 TYR C N   1 
ATOM   8594 C CA  . TYR D 2 240 ? -65.412 12.26   49.01   1   97.24  ? 236 TYR C CA  1 
ATOM   8595 C C   . TYR D 2 240 ? -65.938 12.634  50.398  1   100.02 ? 236 TYR C C   1 
ATOM   8596 O O   . TYR D 2 240 ? -65.987 11.794  51.296  1   97.83  ? 236 TYR C O   1 
ATOM   8597 C CB  . TYR D 2 240 ? -66.491 11.773  48.029  1   100.55 ? 236 TYR C CB  1 
ATOM   8598 C CG  . TYR D 2 240 ? -67.529 12.828  47.65   1   105.47 ? 236 TYR C CG  1 
ATOM   8599 C CD1 . TYR D 2 240 ? -67.292 13.733  46.618  1   106.26 ? 236 TYR C CD1 1 
ATOM   8600 C CD2 . TYR D 2 240 ? -68.737 12.952  48.341  1   109.38 ? 236 TYR C CD2 1 
ATOM   8601 C CE1 . TYR D 2 240 ? -68.218 14.716  46.285  1   109.8  ? 236 TYR C CE1 1 
ATOM   8602 C CE2 . TYR D 2 240 ? -69.672 13.931  48.018  1   112.32 ? 236 TYR C CE2 1 
ATOM   8603 C CZ  . TYR D 2 240 ? -69.41  14.829  46.991  1   113.71 ? 236 TYR C CZ  1 
ATOM   8604 O OH  . TYR D 2 240 ? -70.316 15.815  46.674  1   109.36 ? 236 TYR C OH  1 
ATOM   8605 N N   . LYS D 2 241 ? -66.29  13.911  50.569  1   100.89 ? 237 LYS C N   1 
ATOM   8606 C CA  . LYS D 2 241 ? -66.862 14.41   51.809  1   103.8  ? 237 LYS C CA  1 
ATOM   8607 C C   . LYS D 2 241 ? -68.205 15.073  51.483  1   103.1  ? 237 LYS C C   1 
ATOM   8608 O O   . LYS D 2 241 ? -68.243 16.114  50.814  1   98.72  ? 237 LYS C O   1 
ATOM   8609 C CB  . LYS D 2 241 ? -65.828 15.297  52.518  1   101.22 ? 237 LYS C CB  1 
ATOM   8610 C CG  . LYS D 2 241 ? -64.663 14.559  53.184  1   100.43 ? 237 LYS C CG  1 
ATOM   8611 C CD  . LYS D 2 241 ? -63.446 15.425  53.511  1   99.87  ? 237 LYS C CD  1 
ATOM   8612 C CE  . LYS D 2 241 ? -63.744 16.746  54.19   1   100.63 ? 237 LYS C CE  1 
ATOM   8613 N NZ  . LYS D 2 241 ? -62.581 17.289  54.89   1   91.48  ? 237 LYS C NZ  1 
ATOM   8614 N N   . PRO D 2 242 ? -69.353 14.474  51.899  1   106.77 ? 238 PRO C N   1 
ATOM   8615 C CA  . PRO D 2 242 ? -70.658 15.138  51.77   1   108.7  ? 238 PRO C CA  1 
ATOM   8616 C C   . PRO D 2 242 ? -70.645 16.655  52.004  1   107.02 ? 238 PRO C C   1 
ATOM   8617 O O   . PRO D 2 242 ? -71.467 17.381  51.445  1   105.27 ? 238 PRO C O   1 
ATOM   8618 C CB  . PRO D 2 242 ? -71.554 14.401  52.812  1   105.22 ? 238 PRO C CB  1 
ATOM   8619 C CG  . PRO D 2 242 ? -70.88  13.058  53.084  1   104.97 ? 238 PRO C CG  1 
ATOM   8620 C CD  . PRO D 2 242 ? -69.466 13.131  52.508  1   105.01 ? 238 PRO C CD  1 
ATOM   8621 N N   . SER D 2 243 ? -69.684 17.121  52.82   1   108.06 ? 239 SER C N   1 
ATOM   8622 C CA  . SER D 2 243 ? -69.651 18.465  53.392  1   111.28 ? 239 SER C CA  1 
ATOM   8623 C C   . SER D 2 243 ? -69.042 19.512  52.444  1   109.46 ? 239 SER C C   1 
ATOM   8624 O O   . SER D 2 243 ? -69.084 20.703  52.748  1   109.96 ? 239 SER C O   1 
ATOM   8625 C CB  . SER D 2 243 ? -68.955 18.461  54.745  1   107.2  ? 239 SER C CB  1 
ATOM   8626 O OG  . SER D 2 243 ? -67.601 18.046  54.599  1   108.72 ? 239 SER C OG  1 
ATOM   8627 N N   . PHE D 2 244 ? -68.511 19.041  51.314  1   101.39 ? 240 PHE C N   1 
ATOM   8628 C CA  . PHE D 2 244 ? -67.846 19.94   50.339  1   95.98  ? 240 PHE C CA  1 
ATOM   8629 C C   . PHE D 2 244 ? -68.76  21.087  49.998  1   96.72  ? 240 PHE C C   1 
ATOM   8630 O O   . PHE D 2 244 ? -69.963 20.879  49.779  1   105.84 ? 240 PHE C O   1 
ATOM   8631 C CB  . PHE D 2 244 ? -67.519 19.196  49.044  1   92.19  ? 240 PHE C CB  1 
ATOM   8632 C CG  . PHE D 2 244 ? -66.336 18.242  49.103  1   93.62  ? 240 PHE C CG  1 
ATOM   8633 C CD1 . PHE D 2 244 ? -65.209 18.546  49.853  1   95.33  ? 240 PHE C CD1 1 
ATOM   8634 C CD2 . PHE D 2 244 ? -66.354 17.045  48.399  1   95.21  ? 240 PHE C CD2 1 
ATOM   8635 C CE1 . PHE D 2 244 ? -64.134 17.675  49.898  1   97.92  ? 240 PHE C CE1 1 
ATOM   8636 C CE2 . PHE D 2 244 ? -65.275 16.178  48.449  1   99.88  ? 240 PHE C CE2 1 
ATOM   8637 C CZ  . PHE D 2 244 ? -64.168 16.494  49.198  1   95.54  ? 240 PHE C CZ  1 
ATOM   8638 N N   . PRO D 2 245 ? -68.236 22.325  49.921  1   92.07  ? 241 PRO C N   1 
ATOM   8639 C CA  . PRO D 2 245 ? -69.052 23.438  49.489  1   94.14  ? 241 PRO C CA  1 
ATOM   8640 C C   . PRO D 2 245 ? -69.517 23.171  48.061  1   100.2  ? 241 PRO C C   1 
ATOM   8641 O O   . PRO D 2 245 ? -68.809 22.494  47.298  1   95.28  ? 241 PRO C O   1 
ATOM   8642 C CB  . PRO D 2 245 ? -68.074 24.593  49.627  1   86.61  ? 241 PRO C CB  1 
ATOM   8643 C CG  . PRO D 2 245 ? -67.092 24.125  50.665  1   83.51  ? 241 PRO C CG  1 
ATOM   8644 C CD  . PRO D 2 245 ? -66.878 22.682  50.274  1   85.73  ? 241 PRO C CD  1 
ATOM   8645 N N   . LYS D 2 246 ? -70.701 23.676  47.701  1   108.13 ? 242 LYS C N   1 
ATOM   8646 C CA  . LYS D 2 246 ? -71.278 23.431  46.351  1   101.88 ? 242 LYS C CA  1 
ATOM   8647 C C   . LYS D 2 246 ? -71.108 24.675  45.463  1   95.91  ? 242 LYS C C   1 
ATOM   8648 O O   . LYS D 2 246 ? -72.009 25.531  45.473  1   95.47  ? 242 LYS C O   1 
ATOM   8649 C CB  . LYS D 2 246 ? -72.748 23.016  46.5    1   101.01 ? 242 LYS C CB  1 
ATOM   8650 C CG  . LYS D 2 246 ? -73.007 21.891  47.494  1   97.92  ? 242 LYS C CG  1 
ATOM   8651 C CD  . LYS D 2 246 ? -72.312 20.581  47.143  1   99.68  ? 242 LYS C CD  1 
ATOM   8652 C CE  . LYS D 2 246 ? -72.5   19.525  48.185  1   96.79  ? 242 LYS C CE  1 
ATOM   8653 N NZ  . LYS D 2 246 ? -71.25  18.827  48.493  1   93.45  ? 242 LYS C NZ  1 
ATOM   8654 N N   . TRP D 2 247 ? -70.017 24.743  44.696  1   90.91  ? 243 TRP C N   1 
ATOM   8655 C CA  . TRP D 2 247 ? -69.744 25.912  43.82   1   87.21  ? 243 TRP C CA  1 
ATOM   8656 C C   . TRP D 2 247 ? -70.306 25.673  42.422  1   86.51  ? 243 TRP C C   1 
ATOM   8657 O O   . TRP D 2 247 ? -70.335 24.514  41.979  1   84.01  ? 243 TRP C O   1 
ATOM   8658 C CB  . TRP D 2 247 ? -68.238 26.184  43.725  1   79.45  ? 243 TRP C CB  1 
ATOM   8659 C CG  . TRP D 2 247 ? -67.569 26.622  45      1   76.87  ? 243 TRP C CG  1 
ATOM   8660 C CD1 . TRP D 2 247 ? -67.594 27.864  45.558  1   75.6   ? 243 TRP C CD1 1 
ATOM   8661 C CD2 . TRP D 2 247 ? -66.718 25.819  45.846  1   74.45  ? 243 TRP C CD2 1 
ATOM   8662 N NE1 . TRP D 2 247 ? -66.841 27.887  46.7    1   73.73  ? 243 TRP C NE1 1 
ATOM   8663 C CE2 . TRP D 2 247 ? -66.288 26.651  46.901  1   73.7   ? 243 TRP C CE2 1 
ATOM   8664 C CE3 . TRP D 2 247 ? -66.284 24.491  45.818  1   70.35  ? 243 TRP C CE3 1 
ATOM   8665 C CZ2 . TRP D 2 247 ? -65.447 26.194  47.911  1   73.92  ? 243 TRP C CZ2 1 
ATOM   8666 C CZ3 . TRP D 2 247 ? -65.453 24.042  46.816  1   69.77  ? 243 TRP C CZ3 1 
ATOM   8667 C CH2 . TRP D 2 247 ? -65.036 24.884  47.844  1   72.16  ? 243 TRP C CH2 1 
ATOM   8668 N N   . ALA D 2 248 ? -70.738 26.738  41.75   1   89.01  ? 244 ALA C N   1 
ATOM   8669 C CA  . ALA D 2 248 ? -71.21  26.602  40.349  1   92.17  ? 244 ALA C CA  1 
ATOM   8670 C C   . ALA D 2 248 ? -70.001 26.629  39.407  1   93.84  ? 244 ALA C C   1 
ATOM   8671 O O   . ALA D 2 248 ? -68.961 27.217  39.779  1   94.24  ? 244 ALA C O   1 
ATOM   8672 C CB  . ALA D 2 248 ? -72.191 27.704  40.024  1   90.55  ? 244 ALA C CB  1 
ATOM   8673 N N   . ARG D 2 249 ? -70.125 26.053  38.214  1   93.36  ? 245 ARG C N   1 
ATOM   8674 C CA  . ARG D 2 249 ? -68.974 25.994  37.277  1   93.45  ? 245 ARG C CA  1 
ATOM   8675 C C   . ARG D 2 249 ? -68.588 27.415  36.848  1   98.06  ? 245 ARG C C   1 
ATOM   8676 O O   . ARG D 2 249 ? -69.494 28.225  36.57   1   97.09  ? 245 ARG C O   1 
ATOM   8677 C CB  . ARG D 2 249 ? -69.281 25.14   36.043  1   88.8   ? 245 ARG C CB  1 
ATOM   8678 C CG  . ARG D 2 249 ? -68.637 25.615  34.748  1   89.31  ? 245 ARG C CG  1 
ATOM   8679 C CD  . ARG D 2 249 ? -68.343 24.478  33.79   1   86.83  ? 245 ARG C CD  1 
ATOM   8680 N NE  . ARG D 2 249 ? -67.069 23.821  34.095  1   85.51  ? 245 ARG C NE  1 
ATOM   8681 C CZ  . ARG D 2 249 ? -66.712 22.646  33.604  1   81.85  ? 245 ARG C CZ  1 
ATOM   8682 N NH1 . ARG D 2 249 ? -66.619 21.599  34.401  1   75.58  ? 245 ARG C NH1 1 
ATOM   8683 N NH2 . ARG D 2 249 ? -66.462 22.521  32.314  1   79.65  ? 245 ARG C NH2 1 
ATOM   8684 N N   . GLN D 2 250 ? -67.289 27.703  36.814  1   97.04  ? 246 GLN C N   1 
ATOM   8685 C CA  . GLN D 2 250 ? -66.818 29.031  36.337  1   99.39  ? 246 GLN C CA  1 
ATOM   8686 C C   . GLN D 2 250 ? -66.713 29.009  34.803  1   102.88 ? 246 GLN C C   1 
ATOM   8687 O O   . GLN D 2 250 ? -66.127 28.042  34.267  1   101.24 ? 246 GLN C O   1 
ATOM   8688 C CB  . GLN D 2 250 ? -65.479 29.353  36.999  1   102.49 ? 246 GLN C CB  1 
ATOM   8689 C CG  . GLN D 2 250 ? -64.938 30.743  36.685  1   102.82 ? 246 GLN C CG  1 
ATOM   8690 C CD  . GLN D 2 250 ? -63.517 30.944  37.165  1   101.64 ? 246 GLN C CD  1 
ATOM   8691 O OE1 . GLN D 2 250 ? -62.802 31.842  36.709  1   102.25 ? 246 GLN C OE1 1 
ATOM   8692 N NE2 . GLN D 2 250 ? -63.091 30.096  38.089  1   104.23 ? 246 GLN C NE2 1 
ATOM   8693 N N   . ASP D 2 251 ? -67.251 30.032  34.129  1   108.39 ? 247 ASP C N   1 
ATOM   8694 C CA  . ASP D 2 251 ? -67.235 30.085  32.638  1   105.89 ? 247 ASP C CA  1 
ATOM   8695 C C   . ASP D 2 251 ? -65.79  30.091  32.136  1   98.7   ? 247 ASP C C   1 
ATOM   8696 O O   . ASP D 2 251 ? -64.941 30.738  32.789  1   91.58  ? 247 ASP C O   1 
ATOM   8697 C CB  . ASP D 2 251 ? -67.997 31.29   32.113  1   113.66 ? 247 ASP C CB  1 
ATOM   8698 C CG  . ASP D 2 251 ? -69.509 31.232  32.267  1   129.44 ? 247 ASP C CG  1 
ATOM   8699 O OD1 . ASP D 2 251 ? -70.034 30.13   32.531  1   139.03 ? 247 ASP C OD1 1 
ATOM   8700 O OD2 . ASP D 2 251 ? -70.152 32.292  32.115  1   131.2  ? 247 ASP C OD2 1 
ATOM   8701 N N   . PHE D 2 252 ? -65.521 29.425  31.008  1   99.77  ? 248 PHE C N   1 
ATOM   8702 C CA  . PHE D 2 252 ? -64.143 29.346  30.558  1   100.29 ? 248 PHE C CA  1 
ATOM   8703 C C   . PHE D 2 252 ? -63.712 30.673  29.928  1   103.72 ? 248 PHE C C   1 
ATOM   8704 O O   . PHE D 2 252 ? -62.551 30.815  29.546  1   101.24 ? 248 PHE C O   1 
ATOM   8705 C CB  . PHE D 2 252 ? -64.032 28.097  29.675  1   97.95  ? 248 PHE C CB  1 
ATOM   8706 C CG  . PHE D 2 252 ? -63.82  26.803  30.453  1   100.93 ? 248 PHE C CG  1 
ATOM   8707 C CD1 . PHE D 2 252 ? -64.339 26.63   31.739  1   102.93 ? 248 PHE C CD1 1 
ATOM   8708 C CD2 . PHE D 2 252 ? -63.077 25.761  29.901  1   93.15  ? 248 PHE C CD2 1 
ATOM   8709 C CE1 . PHE D 2 252 ? -64.123 25.447  32.442  1   102.74 ? 248 PHE C CE1 1 
ATOM   8710 C CE2 . PHE D 2 252 ? -62.857 24.588  30.609  1   89.51  ? 248 PHE C CE2 1 
ATOM   8711 C CZ  . PHE D 2 252 ? -63.384 24.425  31.871  1   94.31  ? 248 PHE C CZ  1 
ATOM   8712 N N   . SER D 2 253 ? -64.656 31.627  29.814  1   105.05 ? 249 SER C N   1 
ATOM   8713 C CA  . SER D 2 253 ? -64.396 33.024  29.472  1   109.98 ? 249 SER C CA  1 
ATOM   8714 C C   . SER D 2 253 ? -63.592 33.719  30.58   1   110.11 ? 249 SER C C   1 
ATOM   8715 O O   . SER D 2 253 ? -62.824 34.646  30.314  1   103.79 ? 249 SER C O   1 
ATOM   8716 C CB  . SER D 2 253 ? -65.685 33.793  29.184  1   105.9  ? 249 SER C CB  1 
ATOM   8717 O OG  . SER D 2 253 ? -66.468 33.15   28.189  1   101.13 ? 249 SER C OG  1 
ATOM   8718 N N   . LYS D 2 254 ? -63.796 33.283  31.831  1   108.47 ? 250 LYS C N   1 
ATOM   8719 C CA  . LYS D 2 254 ? -63.104 33.837  32.987  1   102.53 ? 250 LYS C CA  1 
ATOM   8720 C C   . LYS D 2 254 ? -61.819 33.048  33.215  1   91.36  ? 250 LYS C C   1 
ATOM   8721 O O   . LYS D 2 254 ? -60.79  33.639  33.537  1   86.59  ? 250 LYS C O   1 
ATOM   8722 C CB  . LYS D 2 254 ? -63.983 33.737  34.24   1   109.37 ? 250 LYS C CB  1 
ATOM   8723 C CG  . LYS D 2 254 ? -65.402 34.29   34.112  1   122.51 ? 250 LYS C CG  1 
ATOM   8724 C CD  . LYS D 2 254 ? -66.358 33.797  35.2    1   127.54 ? 250 LYS C CD  1 
ATOM   8725 C CE  . LYS D 2 254 ? -67.692 34.494  35.228  1   122.15 ? 250 LYS C CE  1 
ATOM   8726 N NZ  . LYS D 2 254 ? -68.529 33.98   36.313  1   116.43 ? 250 LYS C NZ  1 
ATOM   8727 N N   . VAL D 2 255 ? -61.913 31.721  33.028  1   84.96  ? 251 VAL C N   1 
ATOM   8728 C CA  . VAL D 2 255 ? -60.868 30.768  33.368  1   83.63  ? 251 VAL C CA  1 
ATOM   8729 C C   . VAL D 2 255 ? -59.667 30.953  32.445  1   79.37  ? 251 VAL C C   1 
ATOM   8730 O O   . VAL D 2 255 ? -58.539 31.087  32.916  1   77.52  ? 251 VAL C O   1 
ATOM   8731 C CB  . VAL D 2 255 ? -61.424 29.335  33.309  1   84.27  ? 251 VAL C CB  1 
ATOM   8732 C CG1 . VAL D 2 255 ? -60.327 28.275  33.358  1   80.75  ? 251 VAL C CG1 1 
ATOM   8733 C CG2 . VAL D 2 255 ? -62.473 29.119  34.395  1   87.64  ? 251 VAL C CG2 1 
ATOM   8734 N N   . VAL D 2 256 ? -59.931 30.963  31.139  1   76.15  ? 252 VAL C N   1 
ATOM   8735 C CA  . VAL D 2 256 ? -58.903 31.147  30.129  1   76.93  ? 252 VAL C CA  1 
ATOM   8736 C C   . VAL D 2 256 ? -59.405 32.175  29.115  1   80.91  ? 252 VAL C C   1 
ATOM   8737 O O   . VAL D 2 256 ? -59.855 31.825  28.024  1   79.69  ? 252 VAL C O   1 
ATOM   8738 C CB  . VAL D 2 256 ? -58.463 29.828  29.455  1   71.72  ? 252 VAL C CB  1 
ATOM   8739 C CG1 . VAL D 2 256 ? -57.457 29.067  30.3    1   66.04  ? 252 VAL C CG1 1 
ATOM   8740 C CG2 . VAL D 2 256 ? -59.65  28.946  29.08   1   69.4   ? 252 VAL C CG2 1 
ATOM   8741 N N   . PRO D 2 257 ? -59.373 33.483  29.457  1   85.55  ? 253 PRO C N   1 
ATOM   8742 C CA  . PRO D 2 257 ? -59.888 34.517  28.557  1   89.33  ? 253 PRO C CA  1 
ATOM   8743 C C   . PRO D 2 257 ? -59.348 34.456  27.122  1   96.12  ? 253 PRO C C   1 
ATOM   8744 O O   . PRO D 2 257 ? -60.142 34.534  26.179  1   96.12  ? 253 PRO C O   1 
ATOM   8745 C CB  . PRO D 2 257 ? -59.54  35.828  29.293  1   88.68  ? 253 PRO C CB  1 
ATOM   8746 C CG  . PRO D 2 257 ? -59.49  35.415  30.747  1   88.77  ? 253 PRO C CG  1 
ATOM   8747 C CD  . PRO D 2 257 ? -58.87  34.024  30.73   1   86.76  ? 253 PRO C CD  1 
ATOM   8748 N N   . PRO D 2 258 ? -58.009 34.312  26.895  1   95.34  ? 254 PRO C N   1 
ATOM   8749 C CA  . PRO D 2 258 ? -57.444 34.334  25.536  1   86.21  ? 254 PRO C CA  1 
ATOM   8750 C C   . PRO D 2 258 ? -57.978 33.254  24.604  1   81.07  ? 254 PRO C C   1 
ATOM   8751 O O   . PRO D 2 258 ? -57.868 33.374  23.387  1   79.82  ? 254 PRO C O   1 
ATOM   8752 C CB  . PRO D 2 258 ? -55.909 34.195  25.725  1   84.58  ? 254 PRO C CB  1 
ATOM   8753 C CG  . PRO D 2 258 ? -55.668 34.541  27.183  1   87.02  ? 254 PRO C CG  1 
ATOM   8754 C CD  . PRO D 2 258 ? -56.956 34.185  27.927  1   90.35  ? 254 PRO C CD  1 
ATOM   8755 N N   . LEU D 2 259 ? -58.546 32.197  25.191  1   77.74  ? 255 LEU C N   1 
ATOM   8756 C CA  . LEU D 2 259 ? -58.832 30.973  24.458  1   78.09  ? 255 LEU C CA  1 
ATOM   8757 C C   . LEU D 2 259 ? -60.132 31.111  23.67   1   84.14  ? 255 LEU C C   1 
ATOM   8758 O O   . LEU D 2 259 ? -61.14  31.582  24.205  1   90.14  ? 255 LEU C O   1 
ATOM   8759 C CB  . LEU D 2 259 ? -58.879 29.821  25.463  1   74.62  ? 255 LEU C CB  1 
ATOM   8760 C CG  . LEU D 2 259 ? -58.415 28.456  24.943  1   72.88  ? 255 LEU C CG  1 
ATOM   8761 C CD1 . LEU D 2 259 ? -57.107 28.534  24.14   1   70.76  ? 255 LEU C CD1 1 
ATOM   8762 C CD2 . LEU D 2 259 ? -58.292 27.469  26.101  1   69.1   ? 255 LEU C CD2 1 
ATOM   8763 N N   . ASP D 2 260 ? -60.088 30.703  22.393  1   85.35  ? 256 ASP C N   1 
ATOM   8764 C CA  . ASP D 2 260 ? -61.247 30.688  21.501  1   88.92  ? 256 ASP C CA  1 
ATOM   8765 C C   . ASP D 2 260 ? -62.249 29.616  21.955  1   88.29  ? 256 ASP C C   1 
ATOM   8766 O O   . ASP D 2 260 ? -61.995 28.88   22.919  1   87.15  ? 256 ASP C O   1 
ATOM   8767 C CB  . ASP D 2 260 ? -60.824 30.483  20.048  1   92.27  ? 256 ASP C CB  1 
ATOM   8768 C CG  . ASP D 2 260 ? -59.963 29.247  19.777  1   90.8   ? 256 ASP C CG  1 
ATOM   8769 O OD1 . ASP D 2 260 ? -58.926 29.093  20.459  1   89.28  ? 256 ASP C OD1 1 
ATOM   8770 O OD2 . ASP D 2 260 ? -60.315 28.449  18.877  1   87.88  ? 256 ASP C OD2 1 
ATOM   8771 N N   . GLU D 2 261 ? -63.373 29.51   21.232  1   85.37  ? 257 GLU C N   1 
ATOM   8772 C CA  . GLU D 2 261 ? -64.44  28.584  21.579  1   85.86  ? 257 GLU C CA  1 
ATOM   8773 C C   . GLU D 2 261 ? -64.002 27.12   21.432  1   82.24  ? 257 GLU C C   1 
ATOM   8774 O O   . GLU D 2 261 ? -64.452 26.264  22.19   1   79.55  ? 257 GLU C O   1 
ATOM   8775 C CB  . GLU D 2 261 ? -65.676 28.856  20.726  1   89.96  ? 257 GLU C CB  1 
ATOM   8776 C CG  . GLU D 2 261 ? -66.813 27.892  21.049  1   99.25  ? 257 GLU C CG  1 
ATOM   8777 C CD  . GLU D 2 261 ? -67.979 27.952  20.083  1   114.98 ? 257 GLU C CD  1 
ATOM   8778 O OE1 . GLU D 2 261 ? -68.948 27.199  20.313  1   118.19 ? 257 GLU C OE1 1 
ATOM   8779 O OE2 . GLU D 2 261 ? -67.921 28.738  19.11   1   125.2  ? 257 GLU C OE2 1 
ATOM   8780 N N   . ASP D 2 262 ? -63.155 26.828  20.433  1   80.71  ? 258 ASP C N   1 
ATOM   8781 C CA  . ASP D 2 262 ? -62.626 25.491  20.193  1   77.15  ? 258 ASP C CA  1 
ATOM   8782 C C   . ASP D 2 262 ? -61.679 25.054  21.313  1   71.93  ? 258 ASP C C   1 
ATOM   8783 O O   . ASP D 2 262 ? -61.801 23.935  21.828  1   68.3   ? 258 ASP C O   1 
ATOM   8784 C CB  . ASP D 2 262 ? -62.009 25.391  18.805  1   78.38  ? 258 ASP C CB  1 
ATOM   8785 C CG  . ASP D 2 262 ? -63.031 25.135  17.704  1   82.6   ? 258 ASP C CG  1 
ATOM   8786 O OD1 . ASP D 2 262 ? -64.179 24.796  18.058  1   81.39  ? 258 ASP C OD1 1 
ATOM   8787 O OD2 . ASP D 2 262 ? -62.666 25.256  16.513  1   83.17  ? 258 ASP C OD2 1 
ATOM   8788 N N   . GLY D 2 263 ? -60.736 25.941  21.667  1   66.74  ? 259 GLY C N   1 
ATOM   8789 C CA  . GLY D 2 263 ? -59.813 25.663  22.745  1   61.92  ? 259 GLY C CA  1 
ATOM   8790 C C   . GLY D 2 263 ? -60.57  25.321  24.022  1   62.57  ? 259 GLY C C   1 
ATOM   8791 O O   . GLY D 2 263 ? -60.238 24.343  24.684  1   61.38  ? 259 GLY C O   1 
ATOM   8792 N N   . ARG D 2 264 ? -61.598 26.12   24.335  1   65.81  ? 260 ARG C N   1 
ATOM   8793 C CA  . ARG D 2 264 ? -62.376 26.005  25.563  1   66.79  ? 260 ARG C CA  1 
ATOM   8794 C C   . ARG D 2 264 ? -63.113 24.667  25.614  1   67.16  ? 260 ARG C C   1 
ATOM   8795 O O   . ARG D 2 264 ? -63.223 24.049  26.669  1   69.44  ? 260 ARG C O   1 
ATOM   8796 C CB  . ARG D 2 264 ? -63.368 27.171  25.691  1   69.21  ? 260 ARG C CB  1 
ATOM   8797 C CG  . ARG D 2 264 ? -62.688 28.518  25.909  1   71.52  ? 260 ARG C CG  1 
ATOM   8798 C CD  . ARG D 2 264 ? -63.591 29.65   26.337  1   74.99  ? 260 ARG C CD  1 
ATOM   8799 N NE  . ARG D 2 264 ? -64.873 29.599  25.623  1   79.79  ? 260 ARG C NE  1 
ATOM   8800 C CZ  . ARG D 2 264 ? -65.271 30.438  24.667  1   81.64  ? 260 ARG C CZ  1 
ATOM   8801 N NH1 . ARG D 2 264 ? -64.48  31.42   24.266  1   82.07  ? 260 ARG C NH1 1 
ATOM   8802 N NH2 . ARG D 2 264 ? -66.455 30.28   24.098  1   81.67  ? 260 ARG C NH2 1 
ATOM   8803 N N   . SER D 2 265 ? -63.647 24.247  24.466  1   67.03  ? 261 SER C N   1 
ATOM   8804 C CA  . SER D 2 265 ? -64.318 22.967  24.324  1   65.73  ? 261 SER C CA  1 
ATOM   8805 C C   . SER D 2 265 ? -63.326 21.818  24.555  1   62.34  ? 261 SER C C   1 
ATOM   8806 O O   . SER D 2 265 ? -63.566 20.919  25.357  1   60.65  ? 261 SER C O   1 
ATOM   8807 C CB  . SER D 2 265 ? -65.005 22.906  22.969  1   67.85  ? 261 SER C CB  1 
ATOM   8808 O OG  . SER D 2 265 ? -65.086 21.574  22.489  1   69.09  ? 261 SER C OG  1 
ATOM   8809 N N   . LEU D 2 266 ? -62.177 21.868  23.884  1   58.61  ? 262 LEU C N   1 
ATOM   8810 C CA  . LEU D 2 266 ? -61.159 20.857  24.117  1   58.14  ? 262 LEU C CA  1 
ATOM   8811 C C   . LEU D 2 266 ? -60.721 20.814  25.597  1   57.27  ? 262 LEU C C   1 
ATOM   8812 O O   . LEU D 2 266 ? -60.589 19.729  26.194  1   55.38  ? 262 LEU C O   1 
ATOM   8813 C CB  . LEU D 2 266 ? -59.975 21.082  23.177  1   56.76  ? 262 LEU C CB  1 
ATOM   8814 C CG  . LEU D 2 266 ? -58.767 20.178  23.454  1   55.49  ? 262 LEU C CG  1 
ATOM   8815 C CD1 . LEU D 2 266 ? -59.114 18.732  23.202  1   55.46  ? 262 LEU C CD1 1 
ATOM   8816 C CD2 . LEU D 2 266 ? -57.539 20.593  22.659  1   54.17  ? 262 LEU C CD2 1 
ATOM   8817 N N   . LEU D 2 267 ? -60.493 21.997  26.191  1   55.18  ? 263 LEU C N   1 
ATOM   8818 C CA  . LEU D 2 267 ? -60.055 22.098  27.575  1   53.73  ? 263 LEU C CA  1 
ATOM   8819 C C   . LEU D 2 267 ? -61.078 21.452  28.513  1   55.28  ? 263 LEU C C   1 
ATOM   8820 O O   . LEU D 2 267 ? -60.707 20.625  29.347  1   54.27  ? 263 LEU C O   1 
ATOM   8821 C CB  . LEU D 2 267 ? -59.737 23.55   27.946  1   52.65  ? 263 LEU C CB  1 
ATOM   8822 C CG  . LEU D 2 267 ? -59.271 23.808  29.386  1   51.3   ? 263 LEU C CG  1 
ATOM   8823 C CD1 . LEU D 2 267 ? -58.081 22.938  29.802  1   49.87  ? 263 LEU C CD1 1 
ATOM   8824 C CD2 . LEU D 2 267 ? -58.893 25.257  29.531  1   50.82  ? 263 LEU C CD2 1 
ATOM   8825 N N   . SER D 2 268 ? -62.374 21.754  28.318  1   56.42  ? 264 SER C N   1 
ATOM   8826 C CA  . SER D 2 268 ? -63.384 21.203  29.214  1   58.86  ? 264 SER C CA  1 
ATOM   8827 C C   . SER D 2 268 ? -63.385 19.679  29.146  1   57.7   ? 264 SER C C   1 
ATOM   8828 O O   . SER D 2 268 ? -63.451 19.013  30.176  1   56.58  ? 264 SER C O   1 
ATOM   8829 C CB  . SER D 2 268 ? -64.774 21.79   29.002  1   62.17  ? 264 SER C CB  1 
ATOM   8830 O OG  . SER D 2 268 ? -65.008 22.043  27.624  1   68.55  ? 264 SER C OG  1 
ATOM   8831 N N   . GLN D 2 269 ? -63.297 19.151  27.92   1   58.23  ? 265 GLN C N   1 
ATOM   8832 C CA  . GLN D 2 269 ? -63.279 17.716  27.696  1   59.54  ? 265 GLN C CA  1 
ATOM   8833 C C   . GLN D 2 269 ? -62.033 17.102  28.336  1   59.86  ? 265 GLN C C   1 
ATOM   8834 O O   . GLN D 2 269 ? -62.036 15.929  28.734  1   62.59  ? 265 GLN C O   1 
ATOM   8835 C CB  . GLN D 2 269 ? -63.354 17.395  26.204  1   58.75  ? 265 GLN C CB  1 
ATOM   8836 C CG  . GLN D 2 269 ? -64.702 17.68   25.546  1   61.27  ? 265 GLN C CG  1 
ATOM   8837 C CD  . GLN D 2 269 ? -64.664 17.411  24.052  1   61.94  ? 265 GLN C CD  1 
ATOM   8838 O OE1 . GLN D 2 269 ? -64.659 18.333  23.226  1   61.73  ? 265 GLN C OE1 1 
ATOM   8839 N NE2 . GLN D 2 269 ? -64.569 16.139  23.681  1   61.42  ? 265 GLN C NE2 1 
ATOM   8840 N N   . MET D 2 270 ? -60.949 17.879  28.412  1   56.33  ? 266 MET C N   1 
ATOM   8841 C CA  . MET D 2 270 ? -59.75  17.326  29.029  1   56.17  ? 266 MET C CA  1 
ATOM   8842 C C   . MET D 2 270 ? -59.887 17.287  30.552  1   55.69  ? 266 MET C C   1 
ATOM   8843 O O   . MET D 2 270 ? -59.287 16.43   31.205  1   53.98  ? 266 MET C O   1 
ATOM   8844 C CB  . MET D 2 270 ? -58.504 18.104  28.596  1   51.84  ? 266 MET C CB  1 
ATOM   8845 C CG  . MET D 2 270 ? -58.086 17.647  27.239  1   51.19  ? 266 MET C CG  1 
ATOM   8846 S SD  . MET D 2 270 ? -56.805 18.663  26.511  1   53.76  ? 266 MET C SD  1 
ATOM   8847 C CE  . MET D 2 270 ? -55.392 17.818  27.248  1   49.27  ? 266 MET C CE  1 
ATOM   8848 N N   . LEU D 2 271 ? -60.707 18.203  31.095  1   55.96  ? 267 LEU C N   1 
ATOM   8849 C CA  . LEU D 2 271 ? -60.879 18.339  32.532  1   55.99  ? 267 LEU C CA  1 
ATOM   8850 C C   . LEU D 2 271 ? -62.24  17.807  32.99   1   58.8   ? 267 LEU C C   1 
ATOM   8851 O O   . LEU D 2 271 ? -62.717 18.17   34.056  1   58.73  ? 267 LEU C O   1 
ATOM   8852 C CB  . LEU D 2 271 ? -60.694 19.806  32.9    1   56.06  ? 267 LEU C CB  1 
ATOM   8853 C CG  . LEU D 2 271 ? -59.303 20.402  32.653  1   55.72  ? 267 LEU C CG  1 
ATOM   8854 C CD1 . LEU D 2 271 ? -59.271 21.836  33.143  1   54.98  ? 267 LEU C CD1 1 
ATOM   8855 C CD2 . LEU D 2 271 ? -58.191 19.558  33.29   1   53.94  ? 267 LEU C CD2 1 
ATOM   8856 N N   . HIS D 2 272 ? -62.846 16.898  32.222  1   61     ? 268 HIS C N   1 
ATOM   8857 C CA  . HIS D 2 272 ? -64.051 16.235  32.691  1   64.95  ? 268 HIS C CA  1 
ATOM   8858 C C   . HIS D 2 272 ? -63.725 15.481  33.983  1   62.7   ? 268 HIS C C   1 
ATOM   8859 O O   . HIS D 2 272 ? -62.667 14.859  34.123  1   60.81  ? 268 HIS C O   1 
ATOM   8860 C CB  . HIS D 2 272 ? -64.565 15.278  31.609  1   72.85  ? 268 HIS C CB  1 
ATOM   8861 C CG  . HIS D 2 272 ? -66.044 15.109  31.558  1   85.54  ? 268 HIS C CG  1 
ATOM   8862 N ND1 . HIS D 2 272 ? -66.798 14.649  32.622  1   93.72  ? 268 HIS C ND1 1 
ATOM   8863 C CD2 . HIS D 2 272 ? -66.911 15.38   30.566  1   91.77  ? 268 HIS C CD2 1 
ATOM   8864 C CE1 . HIS D 2 272 ? -68.079 14.635  32.277  1   96.63  ? 268 HIS C CE1 1 
ATOM   8865 N NE2 . HIS D 2 272 ? -68.174 15.075  31.033  1   101.1  ? 268 HIS C NE2 1 
ATOM   8866 N N   . TYR D 2 273 ? -64.647 15.537  34.938  1   62.64  ? 269 TYR C N   1 
ATOM   8867 C CA  . TYR D 2 273 ? -64.43  14.899  36.226  1   63.49  ? 269 TYR C CA  1 
ATOM   8868 C C   . TYR D 2 273 ? -64.444 13.381  36.101  1   63.43  ? 269 TYR C C   1 
ATOM   8869 O O   . TYR D 2 273 ? -63.617 12.7    36.698  1   63.38  ? 269 TYR C O   1 
ATOM   8870 C CB  . TYR D 2 273 ? -65.593 15.236  37.151  1   66.18  ? 269 TYR C CB  1 
ATOM   8871 C CG  . TYR D 2 273 ? -65.423 16.559  37.862  1   70.54  ? 269 TYR C CG  1 
ATOM   8872 C CD1 . TYR D 2 273 ? -64.503 16.688  38.901  1   66.77  ? 269 TYR C CD1 1 
ATOM   8873 C CD2 . TYR D 2 273 ? -66.208 17.663  37.517  1   73.78  ? 269 TYR C CD2 1 
ATOM   8874 C CE1 . TYR D 2 273 ? -64.359 17.897  39.567  1   69.43  ? 269 TYR C CE1 1 
ATOM   8875 C CE2 . TYR D 2 273 ? -66.059 18.878  38.179  1   74.24  ? 269 TYR C CE2 1 
ATOM   8876 C CZ  . TYR D 2 273 ? -65.137 18.996  39.213  1   71.17  ? 269 TYR C CZ  1 
ATOM   8877 O OH  . TYR D 2 273 ? -65.009 20.192  39.872  1   70.85  ? 269 TYR C OH  1 
ATOM   8878 N N   . ASP D 2 274 ? -65.446 12.864  35.381  1   64     ? 270 ASP C N   1 
ATOM   8879 C CA  . ASP D 2 274 ? -65.598 11.438  35.181  1   63.77  ? 270 ASP C CA  1 
ATOM   8880 C C   . ASP D 2 274 ? -64.398 10.969  34.359  1   62.47  ? 270 ASP C C   1 
ATOM   8881 O O   . ASP D 2 274 ? -64.203 11.46   33.241  1   62.83  ? 270 ASP C O   1 
ATOM   8882 C CB  . ASP D 2 274 ? -66.923 11.124  34.491  1   65.34  ? 270 ASP C CB  1 
ATOM   8883 C CG  . ASP D 2 274 ? -67.334 9.664   34.566  1   65.2   ? 270 ASP C CG  1 
ATOM   8884 O OD1 . ASP D 2 274 ? -66.415 8.812   34.602  1   61.61  ? 270 ASP C OD1 1 
ATOM   8885 O OD2 . ASP D 2 274 ? -68.563 9.395   34.584  1   69     ? 270 ASP C OD2 1 
ATOM   8886 N N   . PRO D 2 275 ? -63.534 10.059  34.881  1   61.41  ? 271 PRO C N   1 
ATOM   8887 C CA  . PRO D 2 275 ? -62.432 9.513   34.079  1   60.17  ? 271 PRO C CA  1 
ATOM   8888 C C   . PRO D 2 275 ? -62.909 8.858   32.783  1   63.89  ? 271 PRO C C   1 
ATOM   8889 O O   . PRO D 2 275 ? -62.207 8.914   31.768  1   65.23  ? 271 PRO C O   1 
ATOM   8890 C CB  . PRO D 2 275 ? -61.769 8.503   35.021  1   57.9   ? 271 PRO C CB  1 
ATOM   8891 C CG  . PRO D 2 275 ? -62.127 8.996   36.396  1   58.79  ? 271 PRO C CG  1 
ATOM   8892 C CD  . PRO D 2 275 ? -63.537 9.553   36.265  1   59.83  ? 271 PRO C CD  1 
ATOM   8893 N N   . ASN D 2 276 ? -64.119 8.26    32.823  1   65.94  ? 272 ASN C N   1 
ATOM   8894 C CA  . ASN D 2 276 ? -64.646 7.484   31.711  1   66.02  ? 272 ASN C CA  1 
ATOM   8895 C C   . ASN D 2 276 ? -65.094 8.385   30.559  1   65.33  ? 272 ASN C C   1 
ATOM   8896 O O   . ASN D 2 276 ? -65.098 7.941   29.406  1   64.75  ? 272 ASN C O   1 
ATOM   8897 C CB  . ASN D 2 276 ? -65.77  6.544   32.128  1   71.16  ? 272 ASN C CB  1 
ATOM   8898 C CG  . ASN D 2 276 ? -65.326 5.452   33.073  1   72.51  ? 272 ASN C CG  1 
ATOM   8899 O OD1 . ASN D 2 276 ? -64.333 4.758   32.826  1   72.08  ? 272 ASN C OD1 1 
ATOM   8900 N ND2 . ASN D 2 276 ? -66.067 5.286   34.158  1   72.61  ? 272 ASN C ND2 1 
ATOM   8901 N N   . LYS D 2 277 ? -65.411 9.643   30.886  1   64.29  ? 273 LYS C N   1 
ATOM   8902 C CA  . LYS D 2 277 ? -65.814 10.627  29.85   1   65.44  ? 273 LYS C CA  1 
ATOM   8903 C C   . LYS D 2 277 ? -64.602 11.504  29.496  1   63.62  ? 273 LYS C C   1 
ATOM   8904 O O   . LYS D 2 277 ? -64.628 12.141  28.421  1   64.49  ? 273 LYS C O   1 
ATOM   8905 C CB  . LYS D 2 277 ? -66.968 11.491  30.366  1   71.69  ? 273 LYS C CB  1 
ATOM   8906 C CG  . LYS D 2 277 ? -68.089 10.716  31.039  1   82.64  ? 273 LYS C CG  1 
ATOM   8907 C CD  . LYS D 2 277 ? -69.391 11.502  31.126  1   88.94  ? 273 LYS C CD  1 
ATOM   8908 C CE  . LYS D 2 277 ? -70.359 10.906  32.096  1   90.17  ? 273 LYS C CE  1 
ATOM   8909 N NZ  . LYS D 2 277 ? -70.184 11.454  33.442  1   92.03  ? 273 LYS C NZ  1 
ATOM   8910 N N   . ARG D 2 278 ? -63.629 11.619  30.394  1   58.71  ? 274 ARG C N   1 
ATOM   8911 C CA  . ARG D 2 278 ? -62.418 12.394  30.036  1   52.93  ? 274 ARG C CA  1 
ATOM   8912 C C   . ARG D 2 278 ? -61.994 11.963  28.626  1   51.51  ? 274 ARG C C   1 
ATOM   8913 O O   . ARG D 2 278 ? -61.911 10.751  28.363  1   50.69  ? 274 ARG C O   1 
ATOM   8914 C CB  . ARG D 2 278 ? -61.314 12.27   31.093  1   52.16  ? 274 ARG C CB  1 
ATOM   8915 C CG  . ARG D 2 278 ? -60.288 13.389  31.047  1   49.87  ? 274 ARG C CG  1 
ATOM   8916 C CD  . ARG D 2 278 ? -59.422 13.386  32.288  1   50.09  ? 274 ARG C CD  1 
ATOM   8917 N NE  . ARG D 2 278 ? -60.215 13.568  33.507  1   51.95  ? 274 ARG C NE  1 
ATOM   8918 C CZ  . ARG D 2 278 ? -60.037 12.856  34.604  1   50.5   ? 274 ARG C CZ  1 
ATOM   8919 N NH1 . ARG D 2 278 ? -58.949 12.127  34.738  1   47.37  ? 274 ARG C NH1 1 
ATOM   8920 N NH2 . ARG D 2 278 ? -60.945 12.875  35.559  1   51.65  ? 274 ARG C NH2 1 
ATOM   8921 N N   . ILE D 2 279 ? -61.719 12.932  27.771  1   50.32  ? 275 ILE C N   1 
ATOM   8922 C CA  . ILE D 2 279 ? -61.36  12.656  26.344  1   51.69  ? 275 ILE C CA  1 
ATOM   8923 C C   . ILE D 2 279 ? -60.012 11.921  26.254  1   53.3   ? 275 ILE C C   1 
ATOM   8924 O O   . ILE D 2 279 ? -59.138 12.174  27.113  1   51.86  ? 275 ILE C O   1 
ATOM   8925 C CB  . ILE D 2 279 ? -61.362 13.969  25.535  1   52.5   ? 275 ILE C CB  1 
ATOM   8926 C CG1 . ILE D 2 279 ? -61.425 13.714  24.03   1   54.71  ? 275 ILE C CG1 1 
ATOM   8927 C CG2 . ILE D 2 279 ? -60.174 14.86   25.903  1   51.74  ? 275 ILE C CG2 1 
ATOM   8928 C CD1 . ILE D 2 279 ? -61.305 14.972  23.19   1   55.41  ? 275 ILE C CD1 1 
ATOM   8929 N N   . SER D 2 280 ? -59.858 11.024  25.273  1   55.09  ? 276 SER C N   1 
ATOM   8930 C CA  . SER D 2 280 ? -58.583 10.357  25.066  1   59.55  ? 276 SER C CA  1 
ATOM   8931 C C   . SER D 2 280 ? -57.648 11.295  24.299  1   61.33  ? 276 SER C C   1 
ATOM   8932 O O   . SER D 2 280 ? -58.131 12.205  23.618  1   65.44  ? 276 SER C O   1 
ATOM   8933 C CB  . SER D 2 280 ? -58.798 9.09    24.289  1   59.89  ? 276 SER C CB  1 
ATOM   8934 O OG  . SER D 2 280 ? -59.178 9.402   22.953  1   60.36  ? 276 SER C OG  1 
ATOM   8935 N N   . ALA D 2 281 ? -56.331 11.047  24.37   1   56.92  ? 277 ALA C N   1 
ATOM   8936 C CA  . ALA D 2 281 ? -55.392 11.79   23.541  1   55.06  ? 277 ALA C CA  1 
ATOM   8937 C C   . ALA D 2 281 ? -55.664 11.524  22.059  1   54.36  ? 277 ALA C C   1 
ATOM   8938 O O   . ALA D 2 281 ? -55.591 12.428  21.228  1   55.82  ? 277 ALA C O   1 
ATOM   8939 C CB  . ALA D 2 281 ? -53.961 11.49   23.929  1   51.09  ? 277 ALA C CB  1 
ATOM   8940 N N   . LYS D 2 282 ? -55.992 10.273  21.732  1   54.53  ? 278 LYS C N   1 
ATOM   8941 C CA  . LYS D 2 282 ? -56.384 9.876   20.386  1   55.9   ? 278 LYS C CA  1 
ATOM   8942 C C   . LYS D 2 282 ? -57.528 10.742  19.835  1   57.3   ? 278 LYS C C   1 
ATOM   8943 O O   . LYS D 2 282 ? -57.394 11.361  18.774  1   57.97  ? 278 LYS C O   1 
ATOM   8944 C CB  . LYS D 2 282 ? -56.726 8.385   20.469  1   58.83  ? 278 LYS C CB  1 
ATOM   8945 C CG  . LYS D 2 282 ? -57.095 7.718   19.156  1   62.89  ? 278 LYS C CG  1 
ATOM   8946 C CD  . LYS D 2 282 ? -57.148 6.194   19.22   1   64     ? 278 LYS C CD  1 
ATOM   8947 C CE  . LYS D 2 282 ? -55.784 5.567   19.318  1   63.04  ? 278 LYS C CE  1 
ATOM   8948 N NZ  . LYS D 2 282 ? -55.881 4.122   19.078  1   63.95  ? 278 LYS C NZ  1 
ATOM   8949 N N   . ALA D 2 283 ? -58.655 10.797  20.557  1   57.51  ? 279 ALA C N   1 
ATOM   8950 C CA  . ALA D 2 283 ? -59.794 11.62   20.164  1   59.2   ? 279 ALA C CA  1 
ATOM   8951 C C   . ALA D 2 283 ? -59.39  13.087  20.086  1   60.78  ? 279 ALA C C   1 
ATOM   8952 O O   . ALA D 2 283 ? -59.749 13.773  19.125  1   63.52  ? 279 ALA C O   1 
ATOM   8953 C CB  . ALA D 2 283 ? -60.94  11.449  21.125  1   59.97  ? 279 ALA C CB  1 
ATOM   8954 N N   . ALA D 2 284 ? -58.638 13.555  21.095  1   58.17  ? 280 ALA C N   1 
ATOM   8955 C CA  . ALA D 2 284 ? -58.193 14.938  21.149  1   57.61  ? 280 ALA C CA  1 
ATOM   8956 C C   . ALA D 2 284 ? -57.462 15.373  19.878  1   58.86  ? 280 ALA C C   1 
ATOM   8957 O O   . ALA D 2 284 ? -57.633 16.51   19.442  1   60.05  ? 280 ALA C O   1 
ATOM   8958 C CB  . ALA D 2 284 ? -57.352 15.166  22.362  1   57.31  ? 280 ALA C CB  1 
ATOM   8959 N N   . LEU D 2 285 ? -56.677 14.47   19.272  1   58.63  ? 281 LEU C N   1 
ATOM   8960 C CA  . LEU D 2 285 ? -55.975 14.79   18.033  1   63.18  ? 281 LEU C CA  1 
ATOM   8961 C C   . LEU D 2 285 ? -56.917 15.218  16.896  1   66.17  ? 281 LEU C C   1 
ATOM   8962 O O   . LEU D 2 285 ? -56.492 15.907  15.964  1   67.09  ? 281 LEU C O   1 
ATOM   8963 C CB  . LEU D 2 285 ? -55.116 13.6    17.605  1   65.36  ? 281 LEU C CB  1 
ATOM   8964 C CG  . LEU D 2 285 ? -53.907 13.257  18.484  1   61.28  ? 281 LEU C CG  1 
ATOM   8965 C CD1 . LEU D 2 285 ? -53.023 12.277  17.708  1   58.67  ? 281 LEU C CD1 1 
ATOM   8966 C CD2 . LEU D 2 285 ? -53.151 14.533  18.866  1   56.71  ? 281 LEU C CD2 1 
ATOM   8967 N N   . ALA D 2 286 ? -58.189 14.796  16.964  1   66.79  ? 282 ALA C N   1 
ATOM   8968 C CA  . ALA D 2 286 ? -59.161 15.075  15.913  1   67.76  ? 282 ALA C CA  1 
ATOM   8969 C C   . ALA D 2 286 ? -59.917 16.379  16.165  1   71.04  ? 282 ALA C C   1 
ATOM   8970 O O   . ALA D 2 286 ? -60.566 16.882  15.254  1   72.98  ? 282 ALA C O   1 
ATOM   8971 C CB  . ALA D 2 286 ? -60.135 13.927  15.777  1   65.82  ? 282 ALA C CB  1 
ATOM   8972 N N   . HIS D 2 287 ? -59.838 16.923  17.392  1   69.69  ? 283 HIS C N   1 
ATOM   8973 C CA  . HIS D 2 287 ? -60.679 18.038  17.798  1   65.59  ? 283 HIS C CA  1 
ATOM   8974 C C   . HIS D 2 287 ? -60.505 19.217  16.839  1   67.41  ? 283 HIS C C   1 
ATOM   8975 O O   . HIS D 2 287 ? -59.413 19.431  16.321  1   67.1   ? 283 HIS C O   1 
ATOM   8976 C CB  . HIS D 2 287 ? -60.407 18.393  19.259  1   61.7   ? 283 HIS C CB  1 
ATOM   8977 C CG  . HIS D 2 287 ? -61.372 19.368  19.849  1   63.26  ? 283 HIS C CG  1 
ATOM   8978 N ND1 . HIS D 2 287 ? -61.44  20.676  19.424  1   63.46  ? 283 HIS C ND1 1 
ATOM   8979 C CD2 . HIS D 2 287 ? -62.312 19.241  20.819  1   63.13  ? 283 HIS C CD2 1 
ATOM   8980 C CE1 . HIS D 2 287 ? -62.383 21.317  20.124  1   65.36  ? 283 HIS C CE1 1 
ATOM   8981 N NE2 . HIS D 2 287 ? -62.926 20.463  20.969  1   64.72  ? 283 HIS C NE2 1 
ATOM   8982 N N   . PRO D 2 288 ? -61.583 19.993  16.55   1   68.55  ? 284 PRO C N   1 
ATOM   8983 C CA  . PRO D 2 288 ? -61.505 21.155  15.655  1   70.75  ? 284 PRO C CA  1 
ATOM   8984 C C   . PRO D 2 288 ? -60.462 22.218  16.005  1   68.81  ? 284 PRO C C   1 
ATOM   8985 O O   . PRO D 2 288 ? -60.074 23.034  15.159  1   70.58  ? 284 PRO C O   1 
ATOM   8986 C CB  . PRO D 2 288 ? -62.945 21.747  15.666  1   70.11  ? 284 PRO C CB  1 
ATOM   8987 C CG  . PRO D 2 288 ? -63.813 20.585  16.059  1   71.24  ? 284 PRO C CG  1 
ATOM   8988 C CD  . PRO D 2 288 ? -62.966 19.72   16.986  1   69.42  ? 284 PRO C CD  1 
ATOM   8989 N N   . PHE D 2 289 ? -60.047 22.237  17.27   1   64.95  ? 285 PHE C N   1 
ATOM   8990 C CA  . PHE D 2 289 ? -59.03  23.182  17.686  1   64.39  ? 285 PHE C CA  1 
ATOM   8991 C C   . PHE D 2 289 ? -57.795 23.058  16.791  1   64.13  ? 285 PHE C C   1 
ATOM   8992 O O   . PHE D 2 289 ? -57.156 24.07   16.489  1   65.07  ? 285 PHE C O   1 
ATOM   8993 C CB  . PHE D 2 289 ? -58.688 22.911  19.15   1   63.03  ? 285 PHE C CB  1 
ATOM   8994 C CG  . PHE D 2 289 ? -57.704 23.885  19.776  1   61.95  ? 285 PHE C CG  1 
ATOM   8995 C CD1 . PHE D 2 289 ? -57.97  25.249  19.797  1   62.01  ? 285 PHE C CD1 1 
ATOM   8996 C CD2 . PHE D 2 289 ? -56.523 23.421  20.34   1   60.62  ? 285 PHE C CD2 1 
ATOM   8997 C CE1 . PHE D 2 289 ? -57.089 26.122  20.399  1   62.58  ? 285 PHE C CE1 1 
ATOM   8998 C CE2 . PHE D 2 289 ? -55.623 24.298  20.92   1   61.72  ? 285 PHE C CE2 1 
ATOM   8999 C CZ  . PHE D 2 289 ? -55.924 25.647  20.968  1   63.36  ? 285 PHE C CZ  1 
ATOM   9000 N N   . PHE D 2 290 ? -57.479 21.822  16.368  1   63.08  ? 286 PHE C N   1 
ATOM   9001 C CA  . PHE D 2 290 ? -56.255 21.521  15.632  1   65.04  ? 286 PHE C CA  1 
ATOM   9002 C C   . PHE D 2 290 ? -56.426 21.541  14.107  1   69.91  ? 286 PHE C C   1 
ATOM   9003 O O   . PHE D 2 290 ? -55.486 21.228  13.384  1   69.78  ? 286 PHE C O   1 
ATOM   9004 C CB  . PHE D 2 290 ? -55.681 20.175  16.078  1   59.88  ? 286 PHE C CB  1 
ATOM   9005 C CG  . PHE D 2 290 ? -55.339 20.099  17.558  1   57.77  ? 286 PHE C CG  1 
ATOM   9006 C CD1 . PHE D 2 290 ? -54.344 20.913  18.102  1   55.42  ? 286 PHE C CD1 1 
ATOM   9007 C CD2 . PHE D 2 290 ? -56.006 19.2    18.387  1   55.19  ? 286 PHE C CD2 1 
ATOM   9008 C CE1 . PHE D 2 290 ? -54.025 20.817  19.446  1   54.65  ? 286 PHE C CE1 1 
ATOM   9009 C CE2 . PHE D 2 290 ? -55.692 19.125  19.726  1   53.87  ? 286 PHE C CE2 1 
ATOM   9010 C CZ  . PHE D 2 290 ? -54.702 19.929  20.253  1   53.85  ? 286 PHE C CZ  1 
ATOM   9011 N N   . GLN D 2 291 ? -57.599 21.922  13.598  1   76.54  ? 287 GLN C N   1 
ATOM   9012 C CA  . GLN D 2 291 ? -57.776 22.04   12.158  1   82.23  ? 287 GLN C CA  1 
ATOM   9013 C C   . GLN D 2 291 ? -56.608 22.793  11.511  1   79.98  ? 287 GLN C C   1 
ATOM   9014 O O   . GLN D 2 291 ? -56.074 22.358  10.495  1   80.04  ? 287 GLN C O   1 
ATOM   9015 C CB  . GLN D 2 291 ? -59.118 22.658  11.757  1   90.21  ? 287 GLN C CB  1 
ATOM   9016 C CG  . GLN D 2 291 ? -60.315 21.771  12.098  1   102.16 ? 287 GLN C CG  1 
ATOM   9017 C CD  . GLN D 2 291 ? -61.668 22.377  11.782  1   108.16 ? 287 GLN C CD  1 
ATOM   9018 O OE1 . GLN D 2 291 ? -61.823 23.607  11.73   1   107.75 ? 287 GLN C OE1 1 
ATOM   9019 N NE2 . GLN D 2 291 ? -62.641 21.518  11.491  1   97.44  ? 287 GLN C NE2 1 
ATOM   9020 N N   . ASP D 2 292 ? -56.214 23.924  12.101  1   79.36  ? 288 ASP C N   1 
ATOM   9021 C CA  . ASP D 2 292 ? -55.285 24.844  11.462  1   80.21  ? 288 ASP C CA  1 
ATOM   9022 C C   . ASP D 2 292 ? -53.892 24.745  12.089  1   77.72  ? 288 ASP C C   1 
ATOM   9023 O O   . ASP D 2 292 ? -53.081 25.648  11.91   1   78.86  ? 288 ASP C O   1 
ATOM   9024 C CB  . ASP D 2 292 ? -55.824 26.273  11.494  1   83.53  ? 288 ASP C CB  1 
ATOM   9025 C CG  . ASP D 2 292 ? -56.235 26.793  12.869  1   82.12  ? 288 ASP C CG  1 
ATOM   9026 O OD1 . ASP D 2 292 ? -56.054 26.037  13.855  1   77.7   ? 288 ASP C OD1 1 
ATOM   9027 O OD2 . ASP D 2 292 ? -56.751 27.944  12.946  1   79.57  ? 288 ASP C OD2 1 
ATOM   9028 N N   . VAL D 2 293 ? -53.606 23.644  12.799  1   71.89  ? 289 VAL C N   1 
ATOM   9029 C CA  . VAL D 2 293 ? -52.392 23.569  13.592  1   66.4   ? 289 VAL C CA  1 
ATOM   9030 C C   . VAL D 2 293 ? -51.192 23.743  12.662  1   67.38  ? 289 VAL C C   1 
ATOM   9031 O O   . VAL D 2 293 ? -51.193 23.215  11.557  1   71.12  ? 289 VAL C O   1 
ATOM   9032 C CB  . VAL D 2 293 ? -52.331 22.265  14.408  1   61.09  ? 289 VAL C CB  1 
ATOM   9033 C CG1 . VAL D 2 293 ? -52.3   21.036  13.513  1   61.59  ? 289 VAL C CG1 1 
ATOM   9034 C CG2 . VAL D 2 293 ? -51.136 22.248  15.347  1   57.86  ? 289 VAL C CG2 1 
ATOM   9035 N N   . THR D 2 294 ? -50.203 24.536  13.095  1   66.68  ? 290 THR C N   1 
ATOM   9036 C CA  . THR D 2 294 ? -48.937 24.677  12.384  1   68.55  ? 290 THR C CA  1 
ATOM   9037 C C   . THR D 2 294 ? -47.805 24.297  13.335  1   68.64  ? 290 THR C C   1 
ATOM   9038 O O   . THR D 2 294 ? -48.062 23.9    14.469  1   71.94  ? 290 THR C O   1 
ATOM   9039 C CB  . THR D 2 294 ? -48.759 26.088  11.818  1   70.67  ? 290 THR C CB  1 
ATOM   9040 O OG1 . THR D 2 294 ? -48.826 27.009  12.906  1   72.74  ? 290 THR C OG1 1 
ATOM   9041 C CG2 . THR D 2 294 ? -49.809 26.452  10.784  1   69.9   ? 290 THR C CG2 1 
ATOM   9042 N N   . LYS D 2 295 ? -46.558 24.4    12.865  1   69.62  ? 291 LYS C N   1 
ATOM   9043 C CA  . LYS D 2 295 ? -45.385 24.158  13.694  1   68.23  ? 291 LYS C CA  1 
ATOM   9044 C C   . LYS D 2 295 ? -44.495 25.399  13.673  1   66.23  ? 291 LYS C C   1 
ATOM   9045 O O   . LYS D 2 295 ? -43.487 25.415  12.974  1   68.6   ? 291 LYS C O   1 
ATOM   9046 C CB  . LYS D 2 295 ? -44.59  22.944  13.189  1   70.4   ? 291 LYS C CB  1 
ATOM   9047 C CG  . LYS D 2 295 ? -43.413 22.534  14.08   1   75.65  ? 291 LYS C CG  1 
ATOM   9048 C CD  . LYS D 2 295 ? -42.477 21.44   13.568  1   78.49  ? 291 LYS C CD  1 
ATOM   9049 C CE  . LYS D 2 295 ? -41.749 20.753  14.7    1   80.43  ? 291 LYS C CE  1 
ATOM   9050 N NZ  . LYS D 2 295 ? -40.698 19.835  14.235  1   79.26  ? 291 LYS C NZ  1 
ATOM   9051 N N   . PRO D 2 296 ? -44.832 26.487  14.405  1   64.74  ? 292 PRO C N   1 
ATOM   9052 C CA  . PRO D 2 296 ? -43.944 27.656  14.475  1   64.66  ? 292 PRO C CA  1 
ATOM   9053 C C   . PRO D 2 296 ? -42.714 27.357  15.333  1   65.15  ? 292 PRO C C   1 
ATOM   9054 O O   . PRO D 2 296 ? -42.686 26.355  16.043  1   64.6   ? 292 PRO C O   1 
ATOM   9055 C CB  . PRO D 2 296 ? -44.83  28.78   15.062  1   63.27  ? 292 PRO C CB  1 
ATOM   9056 C CG  . PRO D 2 296 ? -45.974 28.06   15.757  1   60.76  ? 292 PRO C CG  1 
ATOM   9057 C CD  . PRO D 2 296 ? -46.073 26.657  15.176  1   61.3   ? 292 PRO C CD  1 
ATOM   9058 N N   . VAL D 2 297 ? -41.693 28.215  15.231  1   67.75  ? 293 VAL C N   1 
ATOM   9059 C CA  . VAL D 2 297 ? -40.484 28.099  16.042  1   67.38  ? 293 VAL C CA  1 
ATOM   9060 C C   . VAL D 2 297 ? -40.663 29.018  17.254  1   66.99  ? 293 VAL C C   1 
ATOM   9061 O O   . VAL D 2 297 ? -41.211 30.108  17.118  1   69.68  ? 293 VAL C O   1 
ATOM   9062 C CB  . VAL D 2 297 ? -39.158 28.364  15.272  1   65.95  ? 293 VAL C CB  1 
ATOM   9063 C CG1 . VAL D 2 297 ? -38.868 27.336  14.187  1   63.49  ? 293 VAL C CG1 1 
ATOM   9064 C CG2 . VAL D 2 297 ? -39.095 29.736  14.626  1   67.88  ? 293 VAL C CG2 1 
ATOM   9065 N N   . PRO D 2 298 ? -40.26  28.631  18.488  1   64.71  ? 294 PRO C N   1 
ATOM   9066 C CA  . PRO D 2 298 ? -40.367 29.542  19.632  1   65.78  ? 294 PRO C CA  1 
ATOM   9067 C C   . PRO D 2 298 ? -39.458 30.758  19.483  1   74.91  ? 294 PRO C C   1 
ATOM   9068 O O   . PRO D 2 298 ? -38.513 30.746  18.695  1   80.55  ? 294 PRO C O   1 
ATOM   9069 C CB  . PRO D 2 298 ? -39.922 28.673  20.794  1   61.94  ? 294 PRO C CB  1 
ATOM   9070 C CG  . PRO D 2 298 ? -38.994 27.667  20.161  1   61.49  ? 294 PRO C CG  1 
ATOM   9071 C CD  . PRO D 2 298 ? -39.654 27.342  18.832  1   61.36  ? 294 PRO C CD  1 
ATOM   9072 N N   . HIS D 2 299 ? -39.731 31.802  20.265  1   83.96  ? 295 HIS C N   1 
ATOM   9073 C CA  . HIS D 2 299 ? -38.803 32.915  20.368  1   92.92  ? 295 HIS C CA  1 
ATOM   9074 C C   . HIS D 2 299 ? -37.853 32.652  21.538  1   95.18  ? 295 HIS C C   1 
ATOM   9075 O O   . HIS D 2 299 ? -38.218 32.908  22.689  1   104.29 ? 295 HIS C O   1 
ATOM   9076 C CB  . HIS D 2 299 ? -39.566 34.244  20.465  1   104.47 ? 295 HIS C CB  1 
ATOM   9077 C CG  . HIS D 2 299 ? -38.675 35.453  20.541  1   122.44 ? 295 HIS C CG  1 
ATOM   9078 N ND1 . HIS D 2 299 ? -38.471 36.205  21.685  1   124.15 ? 295 HIS C ND1 1 
ATOM   9079 C CD2 . HIS D 2 299 ? -37.941 36.045  19.581  1   125.11 ? 295 HIS C CD2 1 
ATOM   9080 C CE1 . HIS D 2 299 ? -37.638 37.204  21.42   1   122.63 ? 295 HIS C CE1 1 
ATOM   9081 N NE2 . HIS D 2 299 ? -37.306 37.127  20.147  1   128.08 ? 295 HIS C NE2 1 
ATOM   9082 N N   . LEU D 2 300 ? -36.65  32.141  21.226  1   86.24  ? 296 LEU C N   1 
ATOM   9083 C CA  . LEU D 2 300 ? -35.613 31.883  22.214  1   86.4   ? 296 LEU C CA  1 
ATOM   9084 C C   . LEU D 2 300 ? -34.457 32.876  21.998  1   94.79  ? 296 LEU C C   1 
ATOM   9085 O O   . LEU D 2 300 ? -33.448 32.728  22.721  1   99.5   ? 296 LEU C O   1 
ATOM   9086 C CB  . LEU D 2 300 ? -35.118 30.437  22.151  1   82.28  ? 296 LEU C CB  1 
ATOM   9087 C CG  . LEU D 2 300 ? -36.168 29.352  22.415  1   80.61  ? 296 LEU C CG  1 
ATOM   9088 C CD1 . LEU D 2 300 ? -35.657 27.94   22.193  1   72.59  ? 296 LEU C CD1 1 
ATOM   9089 C CD2 . LEU D 2 300 ? -36.699 29.488  23.825  1   83.83  ? 296 LEU C CD2 1 
HETATM 9090 C C4  . IIS E 3 .   ? -23.619 -42.656 7.992   1   55.98  ? 601 IIS A C4  1 
HETATM 9091 C C5  . IIS E 3 .   ? -23.272 -43.261 6.79    1   56.74  ? 601 IIS A C5  1 
HETATM 9092 N N1  . IIS E 3 .   ? -21.006 -41.02  5.292   1   47.37  ? 601 IIS A N1  1 
HETATM 9093 N N2  . IIS E 3 .   ? -22.407 -42.705 5.917   1   52.84  ? 601 IIS A N2  1 
HETATM 9094 C C3  . IIS E 3 .   ? -23.061 -41.404 8.298   1   53.84  ? 601 IIS A C3  1 
HETATM 9095 C C1  . IIS E 3 .   ? -21.878 -41.496 6.193   1   51.68  ? 601 IIS A C1  1 
HETATM 9096 C C2  . IIS E 3 .   ? -22.194 -40.793 7.409   1   49.36  ? 601 IIS A C2  1 
HETATM 9097 I I1  . IIS E 3 .   ? -23.572 -40.436 10.117  1   61.26  ? 601 IIS A I1  1 
HETATM 9098 C C4  A IIS F 3 .   ? -7.853  -22.877 24.622  0.5 77.1   ? 602 IIS A C4  1 
HETATM 9099 C C4  B IIS F 3 .   ? -10.323 -20.849 22.866  0.5 42.27  ? 602 IIS A C4  1 
HETATM 9100 C C5  A IIS F 3 .   ? -9.192  -23.038 24.884  0.5 68.27  ? 602 IIS A C5  1 
HETATM 9101 C C5  B IIS F 3 .   ? -10.808 -21.816 23.705  0.5 40.35  ? 602 IIS A C5  1 
HETATM 9102 N N1  A IIS F 3 .   ? -10.854 -20.8   22.715  0.5 64.07  ? 602 IIS A N1  1 
HETATM 9103 N N1  B IIS F 3 .   ? -7.934  -23.163 25.295  0.5 41.55  ? 602 IIS A N1  1 
HETATM 9104 N N2  A IIS F 3 .   ? -10.174 -22.365 24.257  0.5 66.21  ? 602 IIS A N2  1 
HETATM 9105 N N2  B IIS F 3 .   ? -10.021 -22.569 24.492  0.5 40.95  ? 602 IIS A N2  1 
HETATM 9106 C C3  A IIS F 3 .   ? -7.487  -21.961 23.638  0.5 91.7   ? 602 IIS A C3  1 
HETATM 9107 C C3  B IIS F 3 .   ? -8.943  -20.661 22.841  0.5 45.23  ? 602 IIS A C3  1 
HETATM 9108 C C1  A IIS F 3 .   ? -9.845  -21.462 23.316  0.5 71.28  ? 602 IIS A C1  1 
HETATM 9109 C C1  B IIS F 3 .   ? -8.69   -22.392 24.494  0.5 41.97  ? 602 IIS A C1  1 
HETATM 9110 C C2  A IIS F 3 .   ? -8.476  -21.231 22.972  0.5 80.95  ? 602 IIS A C2  1 
HETATM 9111 C C2  B IIS F 3 .   ? -8.111  -21.412 23.652  0.5 44.05  ? 602 IIS A C2  1 
HETATM 9112 I I1  A IIS F 3 .   ? -5.436  -21.702 23.194  0.5 129.06 ? 602 IIS A I1  1 
HETATM 9113 I I1  B IIS F 3 .   ? -8.105  -19.234 21.578  0.5 52.04  ? 602 IIS A I1  1 
HETATM 9114 C C4  . IIS G 3 .   ? -7.173  -9.35   33.24   1   128.5  ? 603 IIS A C4  1 
HETATM 9115 C C5  . IIS G 3 .   ? -7.824  -8.387  34      1   131.15 ? 603 IIS A C5  1 
HETATM 9116 N N1  . IIS G 3 .   ? -10.346 -10.215 35.708  1   129.58 ? 603 IIS A N1  1 
HETATM 9117 N N2  . IIS G 3 .   ? -8.862  -8.678  34.806  1   136.14 ? 603 IIS A N2  1 
HETATM 9118 C C3  . IIS G 3 .   ? -7.625  -10.675 33.325  1   134.17 ? 603 IIS A C3  1 
HETATM 9119 C C1  . IIS G 3 .   ? -9.311  -9.957  34.887  1   131.77 ? 603 IIS A C1  1 
HETATM 9120 C C2  . IIS G 3 .   ? -8.699  -10.996 34.14   1   124.19 ? 603 IIS A C2  1 
HETATM 9121 I I1  . IIS G 3 .   ? -6.728  -12.22  32.193  1   153.49 ? 603 IIS A I1  1 
HETATM 9122 C C4  . IIS H 3 .   ? -33.017 15.268  27.922  1   47.71  ? 301 IIS C C4  1 
HETATM 9123 C C5  . IIS H 3 .   ? -32.749 16.179  26.951  1   48.39  ? 301 IIS C C5  1 
HETATM 9124 N N1  . IIS H 3 .   ? -32.188 19.183  28.611  1   47     ? 301 IIS C N1  1 
HETATM 9125 N N2  . IIS H 3 .   ? -32.475 17.473  27.191  1   47.49  ? 301 IIS C N2  1 
HETATM 9126 C C3  . IIS H 3 .   ? -33.032 15.74   29.23   1   54.91  ? 301 IIS C C3  1 
HETATM 9127 C C1  . IIS H 3 .   ? -32.449 17.91   28.441  1   46.96  ? 301 IIS C C1  1 
HETATM 9128 C C2  . IIS H 3 .   ? -32.752 17.068  29.514  1   50.93  ? 301 IIS C C2  1 
HETATM 9129 I I1  . IIS H 3 .   ? -33.498 14.417  30.803  1   80.72  ? 301 IIS C I1  1 
HETATM 9130 C C4  . IIS I 3 .   ? -19.344 13.619  31.471  1   78.06  ? 302 IIS C C4  1 
HETATM 9131 C C5  . IIS I 3 .   ? -18.19  13.157  30.882  1   79.83  ? 302 IIS C C5  1 
HETATM 9132 N N1  . IIS I 3 .   ? -16.922 10.805  33.216  1   82.37  ? 302 IIS C N1  1 
HETATM 9133 N N2  . IIS I 3 .   ? -17.394 12.236  31.46   1   81.24  ? 302 IIS C N2  1 
HETATM 9134 C C3  . IIS I 3 .   ? -19.696 13.113  32.73   1   87.72  ? 302 IIS C C3  1 
HETATM 9135 C C1  . IIS I 3 .   ? -17.734 11.722  32.668  1   81.41  ? 302 IIS C C1  1 
HETATM 9136 C C2  . IIS I 3 .   ? -18.9   12.153  33.341  1   78.84  ? 302 IIS C C2  1 
HETATM 9137 I I1  . IIS I 3 .   ? -21.491 13.745  33.675  1   96.5   ? 302 IIS C I1  1 
HETATM 9138 C C4  . IIS J 3 .   ? -62.629 28.132  50.058  1   88.33  ? 303 IIS C C4  1 
HETATM 9139 C C5  . IIS J 3 .   ? -61.631 27.243  50.406  1   84.39  ? 303 IIS C C5  1 
HETATM 9140 N N1  . IIS J 3 .   ? -59.24  27.488  47.785  1   76.22  ? 303 IIS C N1  1 
HETATM 9141 N N2  . IIS J 3 .   ? -60.514 27.046  49.689  1   81.84  ? 303 IIS C N2  1 
HETATM 9142 C C3  . IIS J 3 .   ? -62.482 28.85   48.869  1   96.02  ? 303 IIS C C3  1 
HETATM 9143 C C1  . IIS J 3 .   ? -60.355 27.723  48.529  1   85.56  ? 303 IIS C C1  1 
HETATM 9144 C C2  . IIS J 3 .   ? -61.349 28.644  48.092  1   89     ? 303 IIS C C2  1 
HETATM 9145 I I1  . IIS J 3 .   ? -63.956 30.265  48.249  1   111.21 ? 303 IIS C I1  1 
HETATM 9146 O O   . HOH K 4 .   ? -49.939 -5.207  28.756  1   57.87  ? 501 HOH D O   1 
HETATM 9147 O O   . HOH K 4 .   ? -28.958 -29.567 29.388  1   57.67  ? 502 HOH D O   1 
HETATM 9148 O O   . HOH K 4 .   ? -45.895 -6.295  33.469  1   35.57  ? 503 HOH D O   1 
HETATM 9149 O O   . HOH K 4 .   ? -43.789 -20.26  26.604  1   60.24  ? 504 HOH D O   1 
HETATM 9150 O O   . HOH K 4 .   ? -27.16  -4.515  40.686  1   44.17  ? 505 HOH D O   1 
HETATM 9151 O O   . HOH K 4 .   ? -49.378 -16.284 17.389  1   53.65  ? 506 HOH D O   1 
HETATM 9152 O O   . HOH K 4 .   ? -47.641 -12.627 18.606  1   52.85  ? 507 HOH D O   1 
HETATM 9153 O O   . HOH K 4 .   ? -35.156 -22.748 51.793  1   71.15  ? 508 HOH D O   1 
HETATM 9154 O O   . HOH K 4 .   ? -38.657 -26.849 32.92   1   53.81  ? 509 HOH D O   1 
HETATM 9155 O O   . HOH K 4 .   ? -46     -5.624  28.799  1   50.38  ? 510 HOH D O   1 
HETATM 9156 O O   . HOH K 4 .   ? -46.641 -30.422 31.494  1   54.59  ? 511 HOH D O   1 
HETATM 9157 O O   . HOH K 4 .   ? -25.231 -25.034 31.605  1   51.47  ? 512 HOH D O   1 
HETATM 9158 O O   . HOH K 4 .   ? -28.909 -23.279 44.646  1   56.16  ? 513 HOH D O   1 
HETATM 9159 O O   . HOH K 4 .   ? -48.114 -7.885  45.539  1   42.03  ? 514 HOH D O   1 
HETATM 9160 O O   . HOH K 4 .   ? -22.416 -21.642 43.467  1   63.94  ? 515 HOH D O   1 
HETATM 9161 O O   . HOH K 4 .   ? -20.048 -15.14  42.667  1   46.02  ? 516 HOH D O   1 
HETATM 9162 O O   . HOH K 4 .   ? -61.101 -15.306 49.681  1   60.21  ? 517 HOH D O   1 
HETATM 9163 O O   . HOH K 4 .   ? -36.367 -4.054  45.992  1   53     ? 518 HOH D O   1 
HETATM 9164 O O   . HOH K 4 .   ? -38.956 -3.628  27.682  1   49.32  ? 519 HOH D O   1 
HETATM 9165 O O   . HOH K 4 .   ? -28.554 -23.209 41.923  1   44.3   ? 520 HOH D O   1 
HETATM 9166 O O   . HOH K 4 .   ? -41.013 -1.231  42.285  1   40.97  ? 521 HOH D O   1 
HETATM 9167 O O   . HOH K 4 .   ? -55.344 8.952   26.174  1   47.25  ? 522 HOH D O   1 
HETATM 9168 O O   . HOH K 4 .   ? -46.291 -4.79   46.188  1   52.65  ? 523 HOH D O   1 
HETATM 9169 O O   . HOH K 4 .   ? -46.213 -15.598 30.97   1   46.32  ? 524 HOH D O   1 
HETATM 9170 O O   . HOH K 4 .   ? -46.754 -17.348 43.503  1   48     ? 525 HOH D O   1 
HETATM 9171 O O   . HOH K 4 .   ? -51.524 -11.437 41.678  1   60.26  ? 526 HOH D O   1 
HETATM 9172 O O   . HOH K 4 .   ? -36.503 -27.856 20.405  1   64.81  ? 527 HOH D O   1 
HETATM 9173 O O   . HOH K 4 .   ? -53.736 -12.816 20.814  1   46.6   ? 528 HOH D O   1 
HETATM 9174 O O   . HOH K 4 .   ? -19.574 -12.445 47.186  1   51.08  ? 529 HOH D O   1 
HETATM 9175 O O   . HOH K 4 .   ? -56.469 0.963   19.774  1   61.46  ? 530 HOH D O   1 
HETATM 9176 O O   . HOH K 4 .   ? -43.301 -34.268 37.233  1   65.03  ? 531 HOH D O   1 
HETATM 9177 O O   . HOH K 4 .   ? -27.429 -31.056 30.525  1   58.75  ? 532 HOH D O   1 
HETATM 9178 O O   . HOH K 4 .   ? -22.321 -7.582  37.051  1   49.42  ? 533 HOH D O   1 
HETATM 9179 O O   . HOH K 4 .   ? -45.213 -20.562 30.044  1   55.04  ? 534 HOH D O   1 
HETATM 9180 O O   . HOH K 4 .   ? -43.508 -15.453 30.903  1   51.53  ? 535 HOH D O   1 
HETATM 9181 O O   . HOH K 4 .   ? -44.477 -6.13   30.929  1   42.18  ? 536 HOH D O   1 
HETATM 9182 O O   . HOH K 4 .   ? -39.966 -29.902 30.673  1   55.75  ? 537 HOH D O   1 
HETATM 9183 O O   . HOH K 4 .   ? -33.17  -21.737 49.267  1   61.88  ? 538 HOH D O   1 
HETATM 9184 O O   . HOH K 4 .   ? -52.959 -29.493 51.37   1   61.99  ? 539 HOH D O   1 
HETATM 9185 O O   . HOH K 4 .   ? -34.825 -32.925 32.785  1   58.5   ? 540 HOH D O   1 
HETATM 9186 O O   . HOH K 4 .   ? -18.961 -2.671  32.875  1   74.46  ? 541 HOH D O   1 
HETATM 9187 O O   . HOH K 4 .   ? -46.018 -28.103 37.972  1   59.06  ? 542 HOH D O   1 
HETATM 9188 O O   . HOH K 4 .   ? -46.838 -19.828 19.057  1   53.02  ? 543 HOH D O   1 
HETATM 9189 O O   . HOH K 4 .   ? -38.685 -32.446 30.275  1   61.06  ? 544 HOH D O   1 
HETATM 9190 O O   . HOH K 4 .   ? -31.031 -30.998 28.663  1   61.87  ? 545 HOH D O   1 
HETATM 9191 O O   . HOH K 4 .   ? -29.34  -0.714  26.719  1   49.9   ? 546 HOH D O   1 
HETATM 9192 O O   . HOH K 4 .   ? -48.19  -18.991 17.14   1   59.01  ? 547 HOH D O   1 
HETATM 9193 O O   . HOH K 4 .   ? -44.841 -17.811 29.651  1   52.78  ? 548 HOH D O   1 
HETATM 9194 O O   . HOH L 4 .   ? 4.138   -20.696 -0.993  1   50.94  ? 701 HOH A O   1 
HETATM 9195 O O   . HOH L 4 .   ? -2.788  -20.691 16.742  1   60.23  ? 702 HOH A O   1 
HETATM 9196 O O   . HOH L 4 .   ? -21.907 -17.704 31.422  1   47.33  ? 703 HOH A O   1 
HETATM 9197 O O   . HOH L 4 .   ? 2.258   -29.754 13.048  1   52.8   ? 704 HOH A O   1 
HETATM 9198 O O   . HOH L 4 .   ? -12.762 -28.656 -5.125  1   36.52  ? 705 HOH A O   1 
HETATM 9199 O O   . HOH L 4 .   ? -11.481 -16.366 -9.344  1   54.94  ? 706 HOH A O   1 
HETATM 9200 O O   . HOH L 4 .   ? 0.304   -33.412 8.452   1   36.05  ? 707 HOH A O   1 
HETATM 9201 O O   . HOH L 4 .   ? -19.919 -42.480 20.831  1   64.23  ? 708 HOH A O   1 
HETATM 9202 O O   . HOH L 4 .   ? 5.029   -19.577 -4.824  1   50.91  ? 709 HOH A O   1 
HETATM 9203 O O   . HOH L 4 .   ? -13.698 -11.945 -3.598  1   50.95  ? 710 HOH A O   1 
HETATM 9204 O O   . HOH L 4 .   ? 15.532  -30.956 -13.774 1   48.33  ? 711 HOH A O   1 
HETATM 9205 O O   . HOH L 4 .   ? -19.724 -10.763 3.165   1   48.12  ? 712 HOH A O   1 
HETATM 9206 O O   . HOH L 4 .   ? 1.817   -34.499 15.007  1   47.98  ? 713 HOH A O   1 
HETATM 9207 O O   . HOH L 4 .   ? -1.338  -25.195 -18.621 1   54.13  ? 714 HOH A O   1 
HETATM 9208 O O   . HOH L 4 .   ? 1.135   -38.462 8.233   1   47.07  ? 715 HOH A O   1 
HETATM 9209 O O   . HOH L 4 .   ? 1.915   -32.062 6.177   1   41.59  ? 716 HOH A O   1 
HETATM 9210 O O   . HOH L 4 .   ? -14.119 -27.16  -1.564  1   33.33  ? 717 HOH A O   1 
HETATM 9211 O O   . HOH L 4 .   ? 2.178   -15.509 -8.367  1   51.54  ? 718 HOH A O   1 
HETATM 9212 O O   . HOH L 4 .   ? -13.931 -36.278 -5.13   1   59.22  ? 719 HOH A O   1 
HETATM 9213 O O   . HOH L 4 .   ? -16.426 -38.725 -3.519  1   48.42  ? 720 HOH A O   1 
HETATM 9214 O O   . HOH L 4 .   ? -2.862  -36.356 -5.563  1   47.18  ? 721 HOH A O   1 
HETATM 9215 O O   . HOH L 4 .   ? -19.076 -24.37  19.318  1   36.53  ? 722 HOH A O   1 
HETATM 9216 O O   . HOH L 4 .   ? -4.399  -8.489  5.229   1   48.44  ? 723 HOH A O   1 
HETATM 9217 O O   . HOH L 4 .   ? -12.124 -12.847 -9.298  1   50.27  ? 724 HOH A O   1 
HETATM 9218 O O   . HOH L 4 .   ? -22.269 -18.42  27.837  1   46.63  ? 725 HOH A O   1 
HETATM 9219 O O   . HOH L 4 .   ? -7.035  -12.819 8.165   1   43.89  ? 726 HOH A O   1 
HETATM 9220 O O   . HOH L 4 .   ? -7.796  -16.549 -4.119  1   41.41  ? 727 HOH A O   1 
HETATM 9221 O O   . HOH L 4 .   ? -15.07  -27.426 1.063   1   33.03  ? 728 HOH A O   1 
HETATM 9222 O O   . HOH L 4 .   ? -2.352  -15.415 -3.52   1   37.25  ? 729 HOH A O   1 
HETATM 9223 O O   . HOH L 4 .   ? -12.308 -28.924 -2.513  1   42.44  ? 730 HOH A O   1 
HETATM 9224 O O   . HOH L 4 .   ? -26.817 -20.217 7.994   1   54.01  ? 731 HOH A O   1 
HETATM 9225 O O   . HOH L 4 .   ? -21.845 -44.249 3.717   1   55.11  ? 732 HOH A O   1 
HETATM 9226 O O   . HOH L 4 .   ? -0.185  -13.688 5.647   1   48.31  ? 733 HOH A O   1 
HETATM 9227 O O   . HOH L 4 .   ? -19.232 -21.439 17.026  1   42.75  ? 734 HOH A O   1 
HETATM 9228 O O   . HOH L 4 .   ? 13.787  -32.061 -2.077  1   48.64  ? 735 HOH A O   1 
HETATM 9229 O O   . HOH L 4 .   ? -25.123 -17.268 19.867  1   64.64  ? 736 HOH A O   1 
HETATM 9230 O O   . HOH L 4 .   ? -22.709 -26.868 4.689   1   46.36  ? 737 HOH A O   1 
HETATM 9231 O O   . HOH L 4 .   ? 3.595   -39.768 7.12    1   54.66  ? 738 HOH A O   1 
HETATM 9232 O O   . HOH L 4 .   ? -7.792  -23.661 -4.298  1   42.45  ? 739 HOH A O   1 
HETATM 9233 O O   . HOH L 4 .   ? -3.547  -25.518 2.268   1   33.75  ? 740 HOH A O   1 
HETATM 9234 O O   . HOH L 4 .   ? -5.069  -15.74  -4.52   1   38.36  ? 741 HOH A O   1 
HETATM 9235 O O   . HOH L 4 .   ? -6.001  -24.206 6.077   1   41.28  ? 742 HOH A O   1 
HETATM 9236 O O   . HOH L 4 .   ? -21.797 -28.725 8.407   1   43.56  ? 743 HOH A O   1 
HETATM 9237 O O   . HOH L 4 .   ? -18.813 -6.421  26.033  1   61.67  ? 744 HOH A O   1 
HETATM 9238 O O   . HOH L 4 .   ? 1.313   -29.502 2.259   1   32.09  ? 745 HOH A O   1 
HETATM 9239 O O   . HOH L 4 .   ? -18.025 -18.236 17.406  1   42.31  ? 746 HOH A O   1 
HETATM 9240 O O   . HOH L 4 .   ? -7.529  -18.221 10.431  1   36.94  ? 747 HOH A O   1 
HETATM 9241 O O   . HOH L 4 .   ? -12.394 -49.88  4.539   1   55.42  ? 748 HOH A O   1 
HETATM 9242 O O   . HOH L 4 .   ? 5.515   -41.919 1.333   1   41.42  ? 749 HOH A O   1 
HETATM 9243 O O   . HOH L 4 .   ? -3.305  -5.731  7.519   1   57.88  ? 750 HOH A O   1 
HETATM 9244 O O   . HOH L 4 .   ? -7.95   -10.578 -8.172  1   45.62  ? 751 HOH A O   1 
HETATM 9245 O O   . HOH L 4 .   ? 10.969  -20.89  1.281   1   53.37  ? 752 HOH A O   1 
HETATM 9246 O O   . HOH L 4 .   ? -3.482  -4.448  11.155  1   60.74  ? 753 HOH A O   1 
HETATM 9247 O O   . HOH L 4 .   ? -4.461  -38.024 -4.469  1   54.41  ? 754 HOH A O   1 
HETATM 9248 O O   . HOH L 4 .   ? -8.529  -48.414 16.412  1   54.74  ? 755 HOH A O   1 
HETATM 9249 O O   . HOH L 4 .   ? -20.066 -13.369 -3.555  1   46.01  ? 756 HOH A O   1 
HETATM 9250 O O   . HOH L 4 .   ? 0.47    -37.356 -9.964  1   43.39  ? 757 HOH A O   1 
HETATM 9251 O O   . HOH L 4 .   ? -12.31  -10.783 5.353   1   38.16  ? 758 HOH A O   1 
HETATM 9252 O O   . HOH L 4 .   ? -4.847  -42.897 -5.796  1   55.72  ? 759 HOH A O   1 
HETATM 9253 O O   . HOH L 4 .   ? -15.475 -47.896 6.496   1   56.48  ? 760 HOH A O   1 
HETATM 9254 O O   . HOH L 4 .   ? -9.611  -51.959 3.546   1   60.22  ? 761 HOH A O   1 
HETATM 9255 O O   . HOH L 4 .   ? 4.317   -41.071 3.633   1   45.95  ? 762 HOH A O   1 
HETATM 9256 O O   . HOH L 4 .   ? -22.446 -15.206 17.927  1   58.64  ? 763 HOH A O   1 
HETATM 9257 O O   . HOH L 4 .   ? -6.778  -32.371 30.557  1   67.5   ? 764 HOH A O   1 
HETATM 9258 O O   . HOH L 4 .   ? 7.409   -39.958 0.552   1   47.45  ? 765 HOH A O   1 
HETATM 9259 O O   . HOH L 4 .   ? -15.222 -31.833 -7.775  1   55.51  ? 766 HOH A O   1 
HETATM 9260 O O   . HOH L 4 .   ? -23.662 -29.141 10.277  1   41.79  ? 767 HOH A O   1 
HETATM 9261 O O   . HOH L 4 .   ? 6.715   -19.763 3.244   1   58.35  ? 768 HOH A O   1 
HETATM 9262 O O   . HOH L 4 .   ? -15.746 -41.855 -2.816  1   45.87  ? 769 HOH A O   1 
HETATM 9263 O O   . HOH L 4 .   ? 10.581  -36.902 0.887   1   52.75  ? 770 HOH A O   1 
HETATM 9264 O O   . HOH L 4 .   ? -18.184 -23.996 31.563  1   49.33  ? 771 HOH A O   1 
HETATM 9265 O O   . HOH L 4 .   ? -5.918  -25.068 -11.348 1   51.06  ? 772 HOH A O   1 
HETATM 9266 O O   . HOH L 4 .   ? -17.025 -4.071  25.933  1   52.19  ? 773 HOH A O   1 
HETATM 9267 O O   . HOH L 4 .   ? -16.572 -32.765 -4.163  1   45.81  ? 774 HOH A O   1 
HETATM 9268 O O   . HOH L 4 .   ? 6.545   -28.179 -18.854 1   58.89  ? 775 HOH A O   1 
HETATM 9269 O O   . HOH L 4 .   ? -8.633  -12.007 37.649  1   71.96  ? 776 HOH A O   1 
HETATM 9270 O O   . HOH L 4 .   ? 12.016  -22.17  -1.367  1   40.38  ? 777 HOH A O   1 
HETATM 9271 O O   . HOH L 4 .   ? 14.586  -32.938 2.193   1   56.89  ? 778 HOH A O   1 
HETATM 9272 O O   . HOH L 4 .   ? -9.1    -47.003 -1.979  1   55.49  ? 779 HOH A O   1 
HETATM 9273 O O   . HOH L 4 .   ? 4.829   -21.534 7.858   1   49.23  ? 780 HOH A O   1 
HETATM 9274 O O   . HOH L 4 .   ? -10.384 -11.058 -10.046 1   51.78  ? 781 HOH A O   1 
HETATM 9275 O O   . HOH L 4 .   ? 2.872   -24.773 14.083  1   49.56  ? 782 HOH A O   1 
HETATM 9276 O O   . HOH L 4 .   ? -2.686  -7.169  11.808  1   57.05  ? 783 HOH A O   1 
HETATM 9277 O O   . HOH L 4 .   ? -19.432 -31.36  23.339  1   58.31  ? 784 HOH A O   1 
HETATM 9278 O O   . HOH L 4 .   ? 8.392   -35.653 3.472   1   59.09  ? 785 HOH A O   1 
HETATM 9279 O O   . HOH L 4 .   ? 0.368   -11.097 -1.328  1   51.4   ? 786 HOH A O   1 
HETATM 9280 O O   . HOH L 4 .   ? 5.147   -25.766 9.097   1   62.14  ? 787 HOH A O   1 
HETATM 9281 O O   . HOH L 4 .   ? -14.53  -4.104  31.354  1   60.78  ? 788 HOH A O   1 
HETATM 9282 O O   . HOH L 4 .   ? -1.182  -17.703 -3.559  1   51.12  ? 789 HOH A O   1 
HETATM 9283 O O   . HOH L 4 .   ? 12.772  -36.082 2.325   1   68.82  ? 790 HOH A O   1 
HETATM 9284 O O   . HOH L 4 .   ? -9.212  -19.217 19.167  1   57.58  ? 791 HOH A O   1 
HETATM 9285 O O   . HOH L 4 .   ? -15.715 -44.236 -2.282  1   55.07  ? 792 HOH A O   1 
HETATM 9286 O O   . HOH L 4 .   ? -16.126 -10.176 -0.718  1   54.4   ? 793 HOH A O   1 
HETATM 9287 O O   . HOH L 4 .   ? -19.556 -12.135 42.125  1   56.32  ? 794 HOH A O   1 
HETATM 9288 O O   . HOH M 4 .   ? -30.298 -21.794 -0.518  1   55.9   ? 501 HOH B O   1 
HETATM 9289 O O   . HOH M 4 .   ? -24.915 -5.186  3.407   1   46.3   ? 502 HOH B O   1 
HETATM 9290 O O   . HOH M 4 .   ? -26.171 15.504  11.645  1   59.54  ? 503 HOH B O   1 
HETATM 9291 O O   . HOH M 4 .   ? -13.591 -10.612 -0.28   1   43.62  ? 504 HOH B O   1 
HETATM 9292 O O   . HOH M 4 .   ? -13.962 -21.636 -12.211 1   50.1   ? 505 HOH B O   1 
HETATM 9293 O O   . HOH M 4 .   ? -32.273 -10.311 0.749   1   35.23  ? 506 HOH B O   1 
HETATM 9294 O O   . HOH M 4 .   ? -12.609 -10.139 2.789   1   36.86  ? 507 HOH B O   1 
HETATM 9295 O O   . HOH M 4 .   ? -17.693 -1.143  -7.805  1   49.25  ? 508 HOH B O   1 
HETATM 9296 O O   . HOH M 4 .   ? -8.496  2.378   16.941  1   53.38  ? 509 HOH B O   1 
HETATM 9297 O O   . HOH M 4 .   ? -25.661 2.167   2.174   1   63.87  ? 510 HOH B O   1 
HETATM 9298 O O   . HOH M 4 .   ? -36.564 -13.236 -4.151  1   47.41  ? 511 HOH B O   1 
HETATM 9299 O O   . HOH M 4 .   ? -4.086  -4.567  -0.817  1   60.85  ? 512 HOH B O   1 
HETATM 9300 O O   . HOH M 4 .   ? -5.708  -6.376  5.817   1   43.2   ? 513 HOH B O   1 
HETATM 9301 O O   . HOH M 4 .   ? -6.176  -3.206  -3.873  1   46.21  ? 514 HOH B O   1 
HETATM 9302 O O   . HOH M 4 .   ? -16.626 -8.15   -3.866  1   53.09  ? 515 HOH B O   1 
HETATM 9303 O O   . HOH M 4 .   ? -17.41  -10.876 -5.156  1   53.91  ? 516 HOH B O   1 
HETATM 9304 O O   . HOH M 4 .   ? -20.913 8.227   -17.907 1   40.46  ? 517 HOH B O   1 
HETATM 9305 O O   . HOH M 4 .   ? -21.522 4.628   -19.928 1   52.76  ? 518 HOH B O   1 
HETATM 9306 O O   . HOH M 4 .   ? -11.574 -3.3    -7.409  1   52.29  ? 519 HOH B O   1 
HETATM 9307 O O   . HOH M 4 .   ? -23.092 10.887  17.722  1   44.05  ? 520 HOH B O   1 
HETATM 9308 O O   . HOH M 4 .   ? -21.198 -10.228 -25.895 1   58.39  ? 521 HOH B O   1 
HETATM 9309 O O   . HOH M 4 .   ? -26.025 11.05   -0.624  1   41.03  ? 522 HOH B O   1 
HETATM 9310 O O   . HOH M 4 .   ? -25.367 -26.177 3.779   1   48.37  ? 523 HOH B O   1 
HETATM 9311 O O   . HOH M 4 .   ? -28.635 -23.994 -0.643  1   57.62  ? 524 HOH B O   1 
HETATM 9312 O O   . HOH M 4 .   ? -38.028 -10.954 -15.467 1   51.21  ? 525 HOH B O   1 
HETATM 9313 O O   . HOH M 4 .   ? -21.709 11.305  -12.168 1   50     ? 526 HOH B O   1 
HETATM 9314 O O   . HOH M 4 .   ? -15.296 -9.625  -22.789 1   53.43  ? 527 HOH B O   1 
HETATM 9315 O O   . HOH M 4 .   ? -30.283 -11.972 -5.304  1   38.15  ? 528 HOH B O   1 
HETATM 9316 O O   . HOH M 4 .   ? -19.588 -13.073 -0.877  1   42.88  ? 529 HOH B O   1 
HETATM 9317 O O   . HOH M 4 .   ? -30.544 16.004  2.635   1   50     ? 530 HOH B O   1 
HETATM 9318 O O   . HOH M 4 .   ? -26.776 5.318   -1.622  1   53.17  ? 531 HOH B O   1 
HETATM 9319 O O   . HOH M 4 .   ? -16.082 -8.408  1.625   1   37.86  ? 532 HOH B O   1 
HETATM 9320 O O   . HOH M 4 .   ? 0.464   11.736  8.104   1   50.16  ? 533 HOH B O   1 
HETATM 9321 O O   . HOH M 4 .   ? -27.694 -3.969  3.178   1   53.01  ? 534 HOH B O   1 
HETATM 9322 O O   . HOH M 4 .   ? -18.143 -8.589  3.596   1   33.7   ? 535 HOH B O   1 
HETATM 9323 O O   . HOH M 4 .   ? -18.971 10.164  -8.415  1   48.27  ? 536 HOH B O   1 
HETATM 9324 O O   . HOH M 4 .   ? -16.23  16.524  7.688   1   48.8   ? 537 HOH B O   1 
HETATM 9325 O O   . HOH M 4 .   ? -24.608 -14.275 10.977  1   55.27  ? 538 HOH B O   1 
HETATM 9326 O O   . HOH M 4 .   ? -17.823 -12.962 -11.84  1   47.43  ? 539 HOH B O   1 
HETATM 9327 O O   . HOH M 4 .   ? -5.447  1.609   -17.801 1   68.86  ? 540 HOH B O   1 
HETATM 9328 O O   . HOH M 4 .   ? -32.62  -11.153 -23.554 1   57.82  ? 541 HOH B O   1 
HETATM 9329 O O   . HOH M 4 .   ? -12.22  3.978   -5.843  1   47.6   ? 542 HOH B O   1 
HETATM 9330 O O   . HOH M 4 .   ? -16.255 15.071  -8.203  1   49.72  ? 543 HOH B O   1 
HETATM 9331 O O   . HOH M 4 .   ? -24.067 -24.303 -4.3    1   44.12  ? 544 HOH B O   1 
HETATM 9332 O O   . HOH M 4 .   ? -26.65  10.975  -12.054 1   54.5   ? 545 HOH B O   1 
HETATM 9333 O O   . HOH M 4 .   ? -24.773 -24.383 -1.68   1   42.01  ? 546 HOH B O   1 
HETATM 9334 O O   . HOH M 4 .   ? -24.119 -17.726 -9.203  1   63.06  ? 547 HOH B O   1 
HETATM 9335 O O   . HOH M 4 .   ? -22.658 -2.045  -1.995  1   38.23  ? 548 HOH B O   1 
HETATM 9336 O O   . HOH M 4 .   ? -22.49  -0.841  0.409   1   53.08  ? 549 HOH B O   1 
HETATM 9337 O O   . HOH M 4 .   ? -35.27  -8.626  -1.594  1   46.86  ? 550 HOH B O   1 
HETATM 9338 O O   . HOH M 4 .   ? -6.295  -6.581  -1.648  1   40.69  ? 551 HOH B O   1 
HETATM 9339 O O   . HOH M 4 .   ? -29.326 11.512  13.86   1   55.06  ? 552 HOH B O   1 
HETATM 9340 O O   . HOH M 4 .   ? -29.614 9.12    12.637  1   58.29  ? 553 HOH B O   1 
HETATM 9341 O O   . HOH M 4 .   ? -19.278 10.195  -11.301 1   47.83  ? 554 HOH B O   1 
HETATM 9342 O O   . HOH M 4 .   ? -29.407 -12.684 -20.758 1   63.28  ? 555 HOH B O   1 
HETATM 9343 O O   . HOH M 4 .   ? -29.605 11.727  -2.538  1   47.99  ? 556 HOH B O   1 
HETATM 9344 O O   . HOH M 4 .   ? -7.883  14.175  -0.359  1   59.73  ? 557 HOH B O   1 
HETATM 9345 O O   . HOH M 4 .   ? -31.447 -17.924 -18.57  1   46.8   ? 558 HOH B O   1 
HETATM 9346 O O   . HOH M 4 .   ? -13.756 5.513   21.046  1   51.09  ? 559 HOH B O   1 
HETATM 9347 O O   . HOH M 4 .   ? -22.186 3.283   -26.48  1   54.12  ? 560 HOH B O   1 
HETATM 9348 O O   . HOH M 4 .   ? -17.09  17.367  -7.596  1   58.09  ? 561 HOH B O   1 
HETATM 9349 O O   . HOH M 4 .   ? -9.45   7.484   -11.276 1   46.66  ? 562 HOH B O   1 
HETATM 9350 O O   . HOH M 4 .   ? -32.77  17.157  8.592   1   54.24  ? 563 HOH B O   1 
HETATM 9351 O O   . HOH M 4 .   ? -31.725 9.644   2.375   1   51.86  ? 564 HOH B O   1 
HETATM 9352 O O   . HOH M 4 .   ? -37.123 -2.321  -7.368  1   43.53  ? 565 HOH B O   1 
HETATM 9353 O O   . HOH M 4 .   ? -10.621 -19.116 -12.393 1   51.81  ? 566 HOH B O   1 
HETATM 9354 O O   . HOH M 4 .   ? -24.257 9.337   -8.783  1   48.64  ? 567 HOH B O   1 
HETATM 9355 O O   . HOH M 4 .   ? -35.298 1.524   7.382   1   62.76  ? 568 HOH B O   1 
HETATM 9356 O O   . HOH M 4 .   ? -21.852 10.688  -8.794  1   50.82  ? 569 HOH B O   1 
HETATM 9357 O O   . HOH M 4 .   ? -29.273 17.088  0.313   1   61.12  ? 570 HOH B O   1 
HETATM 9358 O O   . HOH M 4 .   ? -23.14  -10.457 -20.996 1   60.18  ? 571 HOH B O   1 
HETATM 9359 O O   . HOH M 4 .   ? -6.858  -20.895 -10.114 1   50.15  ? 572 HOH B O   1 
HETATM 9360 O O   . HOH M 4 .   ? -19.725 -9.385  10.382  1   51.83  ? 573 HOH B O   1 
HETATM 9361 O O   . HOH M 4 .   ? -30.214 -20.925 -11.56  1   61.67  ? 574 HOH B O   1 
HETATM 9362 O O   . HOH M 4 .   ? -33.512 17.126  11.772  1   63.36  ? 575 HOH B O   1 
HETATM 9363 O O   . HOH M 4 .   ? -32.831 -16.559 -3.33   1   33.17  ? 576 HOH B O   1 
HETATM 9364 O O   . HOH M 4 .   ? -28.49  15.347  17.466  1   61.21  ? 577 HOH B O   1 
HETATM 9365 O O   . HOH M 4 .   ? -13.251 -5.506  -5.586  1   46.8   ? 578 HOH B O   1 
HETATM 9366 O O   . HOH M 4 .   ? -35.362 -4.574  3.223   1   56.58  ? 579 HOH B O   1 
HETATM 9367 O O   . HOH M 4 .   ? -26.158 16.327  -8.545  1   48.81  ? 580 HOH B O   1 
HETATM 9368 O O   . HOH M 4 .   ? -11.628 18.28   14.376  1   45.27  ? 581 HOH B O   1 
HETATM 9369 O O   . HOH M 4 .   ? -23.786 -19.398 -18.105 1   70.29  ? 582 HOH B O   1 
HETATM 9370 O O   . HOH M 4 .   ? -24.555 -28.234 -3.993  1   56.63  ? 583 HOH B O   1 
HETATM 9371 O O   . HOH M 4 .   ? -28.928 11.651  -10.634 1   46.4   ? 584 HOH B O   1 
HETATM 9372 O O   . HOH M 4 .   ? -24.333 9.938   -11.252 1   44.66  ? 585 HOH B O   1 
HETATM 9373 O O   . HOH M 4 .   ? -34.878 -9.604  0.929   1   47.35  ? 586 HOH B O   1 
HETATM 9374 O O   . HOH M 4 .   ? -27.484 -1.683  2.212   1   51.26  ? 587 HOH B O   1 
HETATM 9375 O O   . HOH M 4 .   ? -37.818 -9.483  -2.193  1   54.15  ? 588 HOH B O   1 
HETATM 9376 O O   . HOH M 4 .   ? -36.389 -6.231  -1.869  1   51.44  ? 589 HOH B O   1 
HETATM 9377 O O   . HOH M 4 .   ? -24.837 -0.391  -1.524  1   49.37  ? 590 HOH B O   1 
HETATM 9378 O O   . HOH M 4 .   ? -15.695 -11.498 -10.817 1   43.6   ? 591 HOH B O   1 
HETATM 9379 O O   . HOH M 4 .   ? -36.397 -7.272  2.757   1   49.46  ? 592 HOH B O   1 
HETATM 9380 O O   . HOH N 4 .   ? -28.519 15.976  20.839  1   66.42  ? 401 HOH C O   1 
HETATM 9381 O O   . HOH N 4 .   ? -35.526 12.912  33.148  1   52.34  ? 402 HOH C O   1 
HETATM 9382 O O   . HOH N 4 .   ? -44.082 24.576  16.894  1   47.59  ? 403 HOH C O   1 
HETATM 9383 O O   . HOH N 4 .   ? -45.894 -2.404  35.378  1   42.47  ? 404 HOH C O   1 
HETATM 9384 O O   . HOH N 4 .   ? -54.513 1.894   38.608  1   51.1   ? 405 HOH C O   1 
HETATM 9385 O O   . HOH N 4 .   ? -15.086 11.223  30.675  1   52.34  ? 406 HOH C O   1 
HETATM 9386 O O   . HOH N 4 .   ? -41.216 37.648  29.041  1   66.02  ? 407 HOH C O   1 
HETATM 9387 O O   . HOH N 4 .   ? -55.383 18      52.494  1   56.88  ? 408 HOH C O   1 
HETATM 9388 O O   . HOH N 4 .   ? -42.62  0.965   42.617  1   52.8   ? 409 HOH C O   1 
HETATM 9389 O O   . HOH N 4 .   ? -53.042 13.566  36.986  1   53.69  ? 410 HOH C O   1 
HETATM 9390 O O   . HOH N 4 .   ? -37.58  11.959  19.748  1   51.17  ? 411 HOH C O   1 
HETATM 9391 O O   . HOH N 4 .   ? -57.503 8.027   27.688  1   49.62  ? 412 HOH C O   1 
HETATM 9392 O O   . HOH N 4 .   ? -30.127 17.77   20.145  1   57.34  ? 413 HOH C O   1 
HETATM 9393 O O   . HOH N 4 .   ? -19.381 4.26    25.819  1   58.77  ? 414 HOH C O   1 
HETATM 9394 O O   . HOH N 4 .   ? -58.947 10.32   29.056  1   52.66  ? 415 HOH C O   1 
HETATM 9395 O O   . HOH N 4 .   ? -48.101 -4.138  43.456  1   50.19  ? 416 HOH C O   1 
HETATM 9396 O O   . HOH N 4 .   ? -46.706 17.221  44.523  1   66.09  ? 417 HOH C O   1 
HETATM 9397 O O   . HOH N 4 .   ? -49.322 32.391  27.092  1   62.36  ? 418 HOH C O   1 
HETATM 9398 O O   . HOH N 4 .   ? -40.806 34.656  35.045  1   52.78  ? 419 HOH C O   1 
HETATM 9399 O O   . HOH N 4 .   ? -35.449 0.524   43.611  1   54.09  ? 420 HOH C O   1 
HETATM 9400 O O   . HOH N 4 .   ? -52.637 23.016  37.872  1   53.64  ? 421 HOH C O   1 
HETATM 9401 O O   . HOH N 4 .   ? -42.708 9.456   34.441  1   41.54  ? 422 HOH C O   1 
HETATM 9402 O O   . HOH N 4 .   ? -58.14  7.465   35.497  1   46.96  ? 423 HOH C O   1 
HETATM 9403 O O   . HOH N 4 .   ? -49.592 12.927  34.328  1   44.63  ? 424 HOH C O   1 
HETATM 9404 O O   . HOH N 4 .   ? -54.547 2.233   41.14   1   53.11  ? 425 HOH C O   1 
HETATM 9405 O O   . HOH N 4 .   ? -67.2   29.147  41.616  1   50     ? 426 HOH C O   1 
HETATM 9406 O O   . HOH N 4 .   ? -38.52  8.551   21.409  1   48     ? 427 HOH C O   1 
HETATM 9407 O O   . HOH N 4 .   ? -27.563 10.314  17.837  1   58.46  ? 428 HOH C O   1 
HETATM 9408 O O   . HOH N 4 .   ? -57.661 -5.196  37.653  1   56.21  ? 429 HOH C O   1 
HETATM 9409 O O   . HOH N 4 .   ? -44.488 6.893   43.965  1   55.8   ? 430 HOH C O   1 
HETATM 9410 O O   . HOH N 4 .   ? -23.154 10.945  21.494  1   50.01  ? 431 HOH C O   1 
HETATM 9411 O O   . HOH N 4 .   ? -39.477 0.122   44.064  1   47.47  ? 432 HOH C O   1 
HETATM 9412 O O   . HOH N 4 .   ? -51.635 23.973  35.438  1   51.49  ? 433 HOH C O   1 
HETATM 9413 O O   . HOH N 4 .   ? -24.578 0.251   48.055  1   54.41  ? 434 HOH C O   1 
HETATM 9414 O O   . HOH N 4 .   ? -55.036 19.146  39.222  1   55.9   ? 435 HOH C O   1 
HETATM 9415 O O   . HOH N 4 .   ? -21.87  -0.16   28.576  1   49.77  ? 436 HOH C O   1 
HETATM 9416 O O   . HOH N 4 .   ? -43.848 -0.811  34.79   1   42.94  ? 437 HOH C O   1 
HETATM 9417 O O   . HOH N 4 .   ? -35.817 12.062  30.498  1   48.74  ? 438 HOH C O   1 
HETATM 9418 O O   . HOH N 4 .   ? -61.539 3.221   41.232  1   51.24  ? 439 HOH C O   1 
HETATM 9419 O O   . HOH N 4 .   ? -36.494 7.009   23.383  1   48.81  ? 440 HOH C O   1 
HETATM 9420 O O   . HOH N 4 .   ? -25.941 17.861  18.495  1   57.73  ? 441 HOH C O   1 
HETATM 9421 O O   . HOH N 4 .   ? -38.978 9.474   16.229  1   53.19  ? 442 HOH C O   1 
HETATM 9422 O O   . HOH N 4 .   ? -49.402 3.195   46.951  1   62.89  ? 443 HOH C O   1 
HETATM 9423 O O   . HOH N 4 .   ? -37.76  19.783  15.297  1   60.38  ? 444 HOH C O   1 
HETATM 9424 O O   . HOH N 4 .   ? -15.487 15.475  30.826  1   61.81  ? 445 HOH C O   1 
HETATM 9425 O O   . HOH N 4 .   ? -51.097 34.861  19.421  1   63.55  ? 446 HOH C O   1 
HETATM 9426 O O   . HOH N 4 .   ? -32.344 22.657  21.24   1   52.56  ? 447 HOH C O   1 
HETATM 9427 O O   . HOH N 4 .   ? -62.668 3.408   43.966  1   49.78  ? 448 HOH C O   1 
HETATM 9428 O O   . HOH N 4 .   ? -17.555 5.661   46.887  1   55.6   ? 449 HOH C O   1 
HETATM 9429 O O   . HOH N 4 .   ? -63.138 -4.178  41.341  1   56.95  ? 450 HOH C O   1 
# 
