data_9ET7
# 
_entry.id   9ET7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ET7         pdb_00009et7 10.2210/pdb9et7/pdb 
WWPDB D_1292137044 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ET7 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cyclin-dependent kinase 2'      34354.770 2   2.7.11.22 ? ? ? 
2 polymer     man Cyclin-A2                        30817.473 2   ?         ? ? ? 
3 non-polymer syn '4-bromanyl-1~{H}-pyridin-2-one' 173.995   3   ?         ? ? ? 
4 water       nat water                            18.015    287 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cell division protein kinase 2,p33 protein kinase' 
2 Cyclin-A                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
2 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
B,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 '4-bromanyl-1~{H}-pyridin-2-one' HGQ 
4 water                            HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   SER n 
1 5   MET n 
1 6   GLU n 
1 7   ASN n 
1 8   PHE n 
1 9   GLN n 
1 10  LYS n 
1 11  VAL n 
1 12  GLU n 
1 13  LYS n 
1 14  ILE n 
1 15  GLY n 
1 16  GLU n 
1 17  GLY n 
1 18  THR n 
1 19  TYR n 
1 20  GLY n 
1 21  VAL n 
1 22  VAL n 
1 23  TYR n 
1 24  LYS n 
1 25  ALA n 
1 26  ARG n 
1 27  ASN n 
1 28  LYS n 
1 29  LEU n 
1 30  THR n 
1 31  GLY n 
1 32  GLU n 
1 33  VAL n 
1 34  VAL n 
1 35  ALA n 
1 36  LEU n 
1 37  LYS n 
1 38  LYS n 
1 39  ILE n 
1 40  ARG n 
1 41  LEU n 
1 42  ASP n 
1 43  THR n 
1 44  GLU n 
1 45  THR n 
1 46  GLU n 
1 47  GLY n 
1 48  VAL n 
1 49  PRO n 
1 50  SER n 
1 51  THR n 
1 52  ALA n 
1 53  ILE n 
1 54  ARG n 
1 55  GLU n 
1 56  ILE n 
1 57  SER n 
1 58  LEU n 
1 59  LEU n 
1 60  LYS n 
1 61  GLU n 
1 62  LEU n 
1 63  ASN n 
1 64  HIS n 
1 65  PRO n 
1 66  ASN n 
1 67  ILE n 
1 68  VAL n 
1 69  LYS n 
1 70  LEU n 
1 71  LEU n 
1 72  ASP n 
1 73  VAL n 
1 74  ILE n 
1 75  HIS n 
1 76  THR n 
1 77  GLU n 
1 78  ASN n 
1 79  LYS n 
1 80  LEU n 
1 81  TYR n 
1 82  LEU n 
1 83  VAL n 
1 84  PHE n 
1 85  GLU n 
1 86  PHE n 
1 87  LEU n 
1 88  HIS n 
1 89  GLN n 
1 90  ASP n 
1 91  LEU n 
1 92  LYS n 
1 93  LYS n 
1 94  PHE n 
1 95  MET n 
1 96  ASP n 
1 97  ALA n 
1 98  SER n 
1 99  ALA n 
1 100 LEU n 
1 101 THR n 
1 102 GLY n 
1 103 ILE n 
1 104 PRO n 
1 105 LEU n 
1 106 PRO n 
1 107 LEU n 
1 108 ILE n 
1 109 LYS n 
1 110 SER n 
1 111 TYR n 
1 112 LEU n 
1 113 PHE n 
1 114 GLN n 
1 115 LEU n 
1 116 LEU n 
1 117 GLN n 
1 118 GLY n 
1 119 LEU n 
1 120 ALA n 
1 121 PHE n 
1 122 CYS n 
1 123 HIS n 
1 124 SER n 
1 125 HIS n 
1 126 ARG n 
1 127 VAL n 
1 128 LEU n 
1 129 HIS n 
1 130 ARG n 
1 131 ASP n 
1 132 LEU n 
1 133 LYS n 
1 134 PRO n 
1 135 GLN n 
1 136 ASN n 
1 137 LEU n 
1 138 LEU n 
1 139 ILE n 
1 140 ASN n 
1 141 THR n 
1 142 GLU n 
1 143 GLY n 
1 144 ALA n 
1 145 ILE n 
1 146 LYS n 
1 147 LEU n 
1 148 ALA n 
1 149 ASP n 
1 150 PHE n 
1 151 GLY n 
1 152 LEU n 
1 153 ALA n 
1 154 ARG n 
1 155 ALA n 
1 156 PHE n 
1 157 GLY n 
1 158 VAL n 
1 159 PRO n 
1 160 VAL n 
1 161 ARG n 
1 162 THR n 
1 163 TYR n 
1 164 TPO n 
1 165 HIS n 
1 166 GLU n 
1 167 VAL n 
1 168 VAL n 
1 169 THR n 
1 170 LEU n 
1 171 TRP n 
1 172 TYR n 
1 173 ARG n 
1 174 ALA n 
1 175 PRO n 
1 176 GLU n 
1 177 ILE n 
1 178 LEU n 
1 179 LEU n 
1 180 GLY n 
1 181 CYS n 
1 182 LYS n 
1 183 TYR n 
1 184 TYR n 
1 185 SER n 
1 186 THR n 
1 187 ALA n 
1 188 VAL n 
1 189 ASP n 
1 190 ILE n 
1 191 TRP n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 CYS n 
1 196 ILE n 
1 197 PHE n 
1 198 ALA n 
1 199 GLU n 
1 200 MET n 
1 201 VAL n 
1 202 THR n 
1 203 ARG n 
1 204 ARG n 
1 205 ALA n 
1 206 LEU n 
1 207 PHE n 
1 208 PRO n 
1 209 GLY n 
1 210 ASP n 
1 211 SER n 
1 212 GLU n 
1 213 ILE n 
1 214 ASP n 
1 215 GLN n 
1 216 LEU n 
1 217 PHE n 
1 218 ARG n 
1 219 ILE n 
1 220 PHE n 
1 221 ARG n 
1 222 THR n 
1 223 LEU n 
1 224 GLY n 
1 225 THR n 
1 226 PRO n 
1 227 ASP n 
1 228 GLU n 
1 229 VAL n 
1 230 VAL n 
1 231 TRP n 
1 232 PRO n 
1 233 GLY n 
1 234 VAL n 
1 235 THR n 
1 236 SER n 
1 237 MET n 
1 238 PRO n 
1 239 ASP n 
1 240 TYR n 
1 241 LYS n 
1 242 PRO n 
1 243 SER n 
1 244 PHE n 
1 245 PRO n 
1 246 LYS n 
1 247 TRP n 
1 248 ALA n 
1 249 ARG n 
1 250 GLN n 
1 251 ASP n 
1 252 PHE n 
1 253 SER n 
1 254 LYS n 
1 255 VAL n 
1 256 VAL n 
1 257 PRO n 
1 258 PRO n 
1 259 LEU n 
1 260 ASP n 
1 261 GLU n 
1 262 ASP n 
1 263 GLY n 
1 264 ARG n 
1 265 SER n 
1 266 LEU n 
1 267 LEU n 
1 268 SER n 
1 269 GLN n 
1 270 MET n 
1 271 LEU n 
1 272 HIS n 
1 273 TYR n 
1 274 ASP n 
1 275 PRO n 
1 276 ASN n 
1 277 LYS n 
1 278 ARG n 
1 279 ILE n 
1 280 SER n 
1 281 ALA n 
1 282 LYS n 
1 283 ALA n 
1 284 ALA n 
1 285 LEU n 
1 286 ALA n 
1 287 HIS n 
1 288 PRO n 
1 289 PHE n 
1 290 PHE n 
1 291 GLN n 
1 292 ASP n 
1 293 VAL n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 VAL n 
1 298 PRO n 
1 299 HIS n 
1 300 LEU n 
1 301 ARG n 
1 302 LEU n 
2 1   GLY n 
2 2   VAL n 
2 3   ASN n 
2 4   GLU n 
2 5   VAL n 
2 6   PRO n 
2 7   ASP n 
2 8   TYR n 
2 9   HIS n 
2 10  GLU n 
2 11  ASP n 
2 12  ILE n 
2 13  HIS n 
2 14  THR n 
2 15  TYR n 
2 16  LEU n 
2 17  ARG n 
2 18  GLU n 
2 19  MET n 
2 20  GLU n 
2 21  VAL n 
2 22  LYS n 
2 23  CYS n 
2 24  LYS n 
2 25  PRO n 
2 26  LYS n 
2 27  VAL n 
2 28  GLY n 
2 29  TYR n 
2 30  MET n 
2 31  LYS n 
2 32  LYS n 
2 33  GLN n 
2 34  PRO n 
2 35  ASP n 
2 36  ILE n 
2 37  THR n 
2 38  ASN n 
2 39  SER n 
2 40  MET n 
2 41  ARG n 
2 42  ALA n 
2 43  ILE n 
2 44  LEU n 
2 45  VAL n 
2 46  ASP n 
2 47  TRP n 
2 48  LEU n 
2 49  VAL n 
2 50  GLU n 
2 51  VAL n 
2 52  GLY n 
2 53  GLU n 
2 54  GLU n 
2 55  TYR n 
2 56  LYS n 
2 57  LEU n 
2 58  GLN n 
2 59  ASN n 
2 60  GLU n 
2 61  THR n 
2 62  LEU n 
2 63  HIS n 
2 64  LEU n 
2 65  ALA n 
2 66  VAL n 
2 67  ASN n 
2 68  TYR n 
2 69  ILE n 
2 70  ASP n 
2 71  ARG n 
2 72  PHE n 
2 73  LEU n 
2 74  SER n 
2 75  SER n 
2 76  MET n 
2 77  SER n 
2 78  VAL n 
2 79  LEU n 
2 80  ARG n 
2 81  GLY n 
2 82  LYS n 
2 83  LEU n 
2 84  GLN n 
2 85  LEU n 
2 86  VAL n 
2 87  GLY n 
2 88  THR n 
2 89  ALA n 
2 90  ALA n 
2 91  MET n 
2 92  LEU n 
2 93  LEU n 
2 94  ALA n 
2 95  SER n 
2 96  LYS n 
2 97  PHE n 
2 98  GLU n 
2 99  GLU n 
2 100 ILE n 
2 101 TYR n 
2 102 PRO n 
2 103 PRO n 
2 104 GLU n 
2 105 VAL n 
2 106 ALA n 
2 107 GLU n 
2 108 PHE n 
2 109 VAL n 
2 110 TYR n 
2 111 ILE n 
2 112 THR n 
2 113 ASP n 
2 114 ASP n 
2 115 THR n 
2 116 TYR n 
2 117 THR n 
2 118 LYS n 
2 119 LYS n 
2 120 GLN n 
2 121 VAL n 
2 122 LEU n 
2 123 ARG n 
2 124 MET n 
2 125 GLU n 
2 126 HIS n 
2 127 LEU n 
2 128 VAL n 
2 129 LEU n 
2 130 LYS n 
2 131 VAL n 
2 132 LEU n 
2 133 ALA n 
2 134 PHE n 
2 135 ASP n 
2 136 LEU n 
2 137 ALA n 
2 138 ALA n 
2 139 PRO n 
2 140 THR n 
2 141 ILE n 
2 142 ASN n 
2 143 GLN n 
2 144 PHE n 
2 145 LEU n 
2 146 THR n 
2 147 GLN n 
2 148 TYR n 
2 149 PHE n 
2 150 LEU n 
2 151 HIS n 
2 152 GLN n 
2 153 GLN n 
2 154 PRO n 
2 155 ALA n 
2 156 ASN n 
2 157 CYS n 
2 158 LYS n 
2 159 VAL n 
2 160 GLU n 
2 161 SER n 
2 162 LEU n 
2 163 ALA n 
2 164 MET n 
2 165 PHE n 
2 166 LEU n 
2 167 GLY n 
2 168 GLU n 
2 169 LEU n 
2 170 SER n 
2 171 LEU n 
2 172 ILE n 
2 173 ASP n 
2 174 ALA n 
2 175 ASP n 
2 176 PRO n 
2 177 TYR n 
2 178 LEU n 
2 179 LYS n 
2 180 TYR n 
2 181 LEU n 
2 182 PRO n 
2 183 SER n 
2 184 VAL n 
2 185 ILE n 
2 186 ALA n 
2 187 ALA n 
2 188 ALA n 
2 189 ALA n 
2 190 PHE n 
2 191 HIS n 
2 192 LEU n 
2 193 ALA n 
2 194 LEU n 
2 195 TYR n 
2 196 THR n 
2 197 VAL n 
2 198 THR n 
2 199 GLY n 
2 200 GLN n 
2 201 SER n 
2 202 TRP n 
2 203 PRO n 
2 204 GLU n 
2 205 SER n 
2 206 LEU n 
2 207 VAL n 
2 208 GLN n 
2 209 LYS n 
2 210 THR n 
2 211 GLY n 
2 212 TYR n 
2 213 THR n 
2 214 LEU n 
2 215 GLU n 
2 216 THR n 
2 217 LEU n 
2 218 LYS n 
2 219 PRO n 
2 220 CYS n 
2 221 LEU n 
2 222 LEU n 
2 223 ASP n 
2 224 LEU n 
2 225 HIS n 
2 226 GLN n 
2 227 THR n 
2 228 TYR n 
2 229 LEU n 
2 230 ARG n 
2 231 ALA n 
2 232 PRO n 
2 233 GLN n 
2 234 HIS n 
2 235 ALA n 
2 236 GLN n 
2 237 GLN n 
2 238 SER n 
2 239 ILE n 
2 240 ARG n 
2 241 GLU n 
2 242 LYS n 
2 243 TYR n 
2 244 LYS n 
2 245 ASN n 
2 246 SER n 
2 247 LYS n 
2 248 TYR n 
2 249 HIS n 
2 250 GLY n 
2 251 VAL n 
2 252 SER n 
2 253 LEU n 
2 254 LEU n 
2 255 ASN n 
2 256 PRO n 
2 257 PRO n 
2 258 GLU n 
2 259 THR n 
2 260 LEU n 
2 261 ASN n 
2 262 VAL n 
2 263 HIS n 
2 264 HIS n 
2 265 HIS n 
2 266 HIS n 
2 267 HIS n 
2 268 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
2 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                          ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                         ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                       ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                  ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                         ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                        ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                  ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                          ?                  'C2 H5 N O2'     75.067  
HGQ non-polymer         . '4-bromanyl-1~{H}-pyridin-2-one' ?                  'C5 H4 Br N O'   173.995 
HIS 'L-peptide linking' y HISTIDINE                        ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                            ?                  'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                       ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                          ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                           ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                       ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                    ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                          ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                           ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                        ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE                 PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN                       ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                         ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                           ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -3  -3  GLY GLY A . n 
A 1 2   PRO 2   -2  -2  PRO PRO A . n 
A 1 3   GLY 3   -1  -1  GLY GLY A . n 
A 1 4   SER 4   0   0   SER SER A . n 
A 1 5   MET 5   1   1   MET MET A . n 
A 1 6   GLU 6   2   2   GLU GLU A . n 
A 1 7   ASN 7   3   3   ASN ASN A . n 
A 1 8   PHE 8   4   4   PHE PHE A . n 
A 1 9   GLN 9   5   5   GLN GLN A . n 
A 1 10  LYS 10  6   6   LYS LYS A . n 
A 1 11  VAL 11  7   7   VAL VAL A . n 
A 1 12  GLU 12  8   8   GLU GLU A . n 
A 1 13  LYS 13  9   9   LYS LYS A . n 
A 1 14  ILE 14  10  10  ILE ILE A . n 
A 1 15  GLY 15  11  11  GLY GLY A . n 
A 1 16  GLU 16  12  12  GLU GLU A . n 
A 1 17  GLY 17  13  13  GLY GLY A . n 
A 1 18  THR 18  14  14  THR THR A . n 
A 1 19  TYR 19  15  15  TYR TYR A . n 
A 1 20  GLY 20  16  16  GLY GLY A . n 
A 1 21  VAL 21  17  17  VAL VAL A . n 
A 1 22  VAL 22  18  18  VAL VAL A . n 
A 1 23  TYR 23  19  19  TYR TYR A . n 
A 1 24  LYS 24  20  20  LYS LYS A . n 
A 1 25  ALA 25  21  21  ALA ALA A . n 
A 1 26  ARG 26  22  22  ARG ARG A . n 
A 1 27  ASN 27  23  23  ASN ASN A . n 
A 1 28  LYS 28  24  24  LYS LYS A . n 
A 1 29  LEU 29  25  25  LEU LEU A . n 
A 1 30  THR 30  26  26  THR THR A . n 
A 1 31  GLY 31  27  27  GLY GLY A . n 
A 1 32  GLU 32  28  28  GLU GLU A . n 
A 1 33  VAL 33  29  29  VAL VAL A . n 
A 1 34  VAL 34  30  30  VAL VAL A . n 
A 1 35  ALA 35  31  31  ALA ALA A . n 
A 1 36  LEU 36  32  32  LEU LEU A . n 
A 1 37  LYS 37  33  33  LYS LYS A . n 
A 1 38  LYS 38  34  34  LYS LYS A . n 
A 1 39  ILE 39  35  35  ILE ILE A . n 
A 1 40  ARG 40  36  36  ARG ARG A . n 
A 1 41  LEU 41  37  37  LEU LEU A . n 
A 1 42  ASP 42  38  38  ASP ASP A . n 
A 1 43  THR 43  39  39  THR THR A . n 
A 1 44  GLU 44  40  40  GLU GLU A . n 
A 1 45  THR 45  41  41  THR THR A . n 
A 1 46  GLU 46  42  42  GLU GLU A . n 
A 1 47  GLY 47  43  43  GLY GLY A . n 
A 1 48  VAL 48  44  44  VAL VAL A . n 
A 1 49  PRO 49  45  45  PRO PRO A . n 
A 1 50  SER 50  46  46  SER SER A . n 
A 1 51  THR 51  47  47  THR THR A . n 
A 1 52  ALA 52  48  48  ALA ALA A . n 
A 1 53  ILE 53  49  49  ILE ILE A . n 
A 1 54  ARG 54  50  50  ARG ARG A . n 
A 1 55  GLU 55  51  51  GLU GLU A . n 
A 1 56  ILE 56  52  52  ILE ILE A . n 
A 1 57  SER 57  53  53  SER SER A . n 
A 1 58  LEU 58  54  54  LEU LEU A . n 
A 1 59  LEU 59  55  55  LEU LEU A . n 
A 1 60  LYS 60  56  56  LYS LYS A . n 
A 1 61  GLU 61  57  57  GLU GLU A . n 
A 1 62  LEU 62  58  58  LEU LEU A . n 
A 1 63  ASN 63  59  59  ASN ASN A . n 
A 1 64  HIS 64  60  60  HIS HIS A . n 
A 1 65  PRO 65  61  61  PRO PRO A . n 
A 1 66  ASN 66  62  62  ASN ASN A . n 
A 1 67  ILE 67  63  63  ILE ILE A . n 
A 1 68  VAL 68  64  64  VAL VAL A . n 
A 1 69  LYS 69  65  65  LYS LYS A . n 
A 1 70  LEU 70  66  66  LEU LEU A . n 
A 1 71  LEU 71  67  67  LEU LEU A . n 
A 1 72  ASP 72  68  68  ASP ASP A . n 
A 1 73  VAL 73  69  69  VAL VAL A . n 
A 1 74  ILE 74  70  70  ILE ILE A . n 
A 1 75  HIS 75  71  71  HIS HIS A . n 
A 1 76  THR 76  72  72  THR THR A . n 
A 1 77  GLU 77  73  73  GLU GLU A . n 
A 1 78  ASN 78  74  74  ASN ASN A . n 
A 1 79  LYS 79  75  75  LYS LYS A . n 
A 1 80  LEU 80  76  76  LEU LEU A . n 
A 1 81  TYR 81  77  77  TYR TYR A . n 
A 1 82  LEU 82  78  78  LEU LEU A . n 
A 1 83  VAL 83  79  79  VAL VAL A . n 
A 1 84  PHE 84  80  80  PHE PHE A . n 
A 1 85  GLU 85  81  81  GLU GLU A . n 
A 1 86  PHE 86  82  82  PHE PHE A . n 
A 1 87  LEU 87  83  83  LEU LEU A . n 
A 1 88  HIS 88  84  84  HIS HIS A . n 
A 1 89  GLN 89  85  85  GLN GLN A . n 
A 1 90  ASP 90  86  86  ASP ASP A . n 
A 1 91  LEU 91  87  87  LEU LEU A . n 
A 1 92  LYS 92  88  88  LYS LYS A . n 
A 1 93  LYS 93  89  89  LYS LYS A . n 
A 1 94  PHE 94  90  90  PHE PHE A . n 
A 1 95  MET 95  91  91  MET MET A . n 
A 1 96  ASP 96  92  92  ASP ASP A . n 
A 1 97  ALA 97  93  93  ALA ALA A . n 
A 1 98  SER 98  94  94  SER SER A . n 
A 1 99  ALA 99  95  95  ALA ALA A . n 
A 1 100 LEU 100 96  96  LEU LEU A . n 
A 1 101 THR 101 97  97  THR THR A . n 
A 1 102 GLY 102 98  98  GLY GLY A . n 
A 1 103 ILE 103 99  99  ILE ILE A . n 
A 1 104 PRO 104 100 100 PRO PRO A . n 
A 1 105 LEU 105 101 101 LEU LEU A . n 
A 1 106 PRO 106 102 102 PRO PRO A . n 
A 1 107 LEU 107 103 103 LEU LEU A . n 
A 1 108 ILE 108 104 104 ILE ILE A . n 
A 1 109 LYS 109 105 105 LYS LYS A . n 
A 1 110 SER 110 106 106 SER SER A . n 
A 1 111 TYR 111 107 107 TYR TYR A . n 
A 1 112 LEU 112 108 108 LEU LEU A . n 
A 1 113 PHE 113 109 109 PHE PHE A . n 
A 1 114 GLN 114 110 110 GLN GLN A . n 
A 1 115 LEU 115 111 111 LEU LEU A . n 
A 1 116 LEU 116 112 112 LEU LEU A . n 
A 1 117 GLN 117 113 113 GLN GLN A . n 
A 1 118 GLY 118 114 114 GLY GLY A . n 
A 1 119 LEU 119 115 115 LEU LEU A . n 
A 1 120 ALA 120 116 116 ALA ALA A . n 
A 1 121 PHE 121 117 117 PHE PHE A . n 
A 1 122 CYS 122 118 118 CYS CYS A . n 
A 1 123 HIS 123 119 119 HIS HIS A . n 
A 1 124 SER 124 120 120 SER SER A . n 
A 1 125 HIS 125 121 121 HIS HIS A . n 
A 1 126 ARG 126 122 122 ARG ARG A . n 
A 1 127 VAL 127 123 123 VAL VAL A . n 
A 1 128 LEU 128 124 124 LEU LEU A . n 
A 1 129 HIS 129 125 125 HIS HIS A . n 
A 1 130 ARG 130 126 126 ARG ARG A . n 
A 1 131 ASP 131 127 127 ASP ASP A . n 
A 1 132 LEU 132 128 128 LEU LEU A . n 
A 1 133 LYS 133 129 129 LYS LYS A . n 
A 1 134 PRO 134 130 130 PRO PRO A . n 
A 1 135 GLN 135 131 131 GLN GLN A . n 
A 1 136 ASN 136 132 132 ASN ASN A . n 
A 1 137 LEU 137 133 133 LEU LEU A . n 
A 1 138 LEU 138 134 134 LEU LEU A . n 
A 1 139 ILE 139 135 135 ILE ILE A . n 
A 1 140 ASN 140 136 136 ASN ASN A . n 
A 1 141 THR 141 137 137 THR THR A . n 
A 1 142 GLU 142 138 138 GLU GLU A . n 
A 1 143 GLY 143 139 139 GLY GLY A . n 
A 1 144 ALA 144 140 140 ALA ALA A . n 
A 1 145 ILE 145 141 141 ILE ILE A . n 
A 1 146 LYS 146 142 142 LYS LYS A . n 
A 1 147 LEU 147 143 143 LEU LEU A . n 
A 1 148 ALA 148 144 144 ALA ALA A . n 
A 1 149 ASP 149 145 145 ASP ASP A . n 
A 1 150 PHE 150 146 146 PHE PHE A . n 
A 1 151 GLY 151 147 147 GLY GLY A . n 
A 1 152 LEU 152 148 148 LEU LEU A . n 
A 1 153 ALA 153 149 149 ALA ALA A . n 
A 1 154 ARG 154 150 150 ARG ARG A . n 
A 1 155 ALA 155 151 151 ALA ALA A . n 
A 1 156 PHE 156 152 152 PHE PHE A . n 
A 1 157 GLY 157 153 153 GLY GLY A . n 
A 1 158 VAL 158 154 154 VAL VAL A . n 
A 1 159 PRO 159 155 155 PRO PRO A . n 
A 1 160 VAL 160 156 156 VAL VAL A . n 
A 1 161 ARG 161 157 157 ARG ARG A . n 
A 1 162 THR 162 158 158 THR THR A . n 
A 1 163 TYR 163 159 159 TYR TYR A . n 
A 1 164 TPO 164 160 160 TPO TPO A . n 
A 1 165 HIS 165 161 161 HIS HIS A . n 
A 1 166 GLU 166 162 162 GLU GLU A . n 
A 1 167 VAL 167 163 163 VAL VAL A . n 
A 1 168 VAL 168 164 164 VAL VAL A . n 
A 1 169 THR 169 165 165 THR THR A . n 
A 1 170 LEU 170 166 166 LEU LEU A . n 
A 1 171 TRP 171 167 167 TRP TRP A . n 
A 1 172 TYR 172 168 168 TYR TYR A . n 
A 1 173 ARG 173 169 169 ARG ARG A . n 
A 1 174 ALA 174 170 170 ALA ALA A . n 
A 1 175 PRO 175 171 171 PRO PRO A . n 
A 1 176 GLU 176 172 172 GLU GLU A . n 
A 1 177 ILE 177 173 173 ILE ILE A . n 
A 1 178 LEU 178 174 174 LEU LEU A . n 
A 1 179 LEU 179 175 175 LEU LEU A . n 
A 1 180 GLY 180 176 176 GLY GLY A . n 
A 1 181 CYS 181 177 177 CYS CYS A . n 
A 1 182 LYS 182 178 178 LYS LYS A . n 
A 1 183 TYR 183 179 179 TYR TYR A . n 
A 1 184 TYR 184 180 180 TYR TYR A . n 
A 1 185 SER 185 181 181 SER SER A . n 
A 1 186 THR 186 182 182 THR THR A . n 
A 1 187 ALA 187 183 183 ALA ALA A . n 
A 1 188 VAL 188 184 184 VAL VAL A . n 
A 1 189 ASP 189 185 185 ASP ASP A . n 
A 1 190 ILE 190 186 186 ILE ILE A . n 
A 1 191 TRP 191 187 187 TRP TRP A . n 
A 1 192 SER 192 188 188 SER SER A . n 
A 1 193 LEU 193 189 189 LEU LEU A . n 
A 1 194 GLY 194 190 190 GLY GLY A . n 
A 1 195 CYS 195 191 191 CYS CYS A . n 
A 1 196 ILE 196 192 192 ILE ILE A . n 
A 1 197 PHE 197 193 193 PHE PHE A . n 
A 1 198 ALA 198 194 194 ALA ALA A . n 
A 1 199 GLU 199 195 195 GLU GLU A . n 
A 1 200 MET 200 196 196 MET MET A . n 
A 1 201 VAL 201 197 197 VAL VAL A . n 
A 1 202 THR 202 198 198 THR THR A . n 
A 1 203 ARG 203 199 199 ARG ARG A . n 
A 1 204 ARG 204 200 200 ARG ARG A . n 
A 1 205 ALA 205 201 201 ALA ALA A . n 
A 1 206 LEU 206 202 202 LEU LEU A . n 
A 1 207 PHE 207 203 203 PHE PHE A . n 
A 1 208 PRO 208 204 204 PRO PRO A . n 
A 1 209 GLY 209 205 205 GLY GLY A . n 
A 1 210 ASP 210 206 206 ASP ASP A . n 
A 1 211 SER 211 207 207 SER SER A . n 
A 1 212 GLU 212 208 208 GLU GLU A . n 
A 1 213 ILE 213 209 209 ILE ILE A . n 
A 1 214 ASP 214 210 210 ASP ASP A . n 
A 1 215 GLN 215 211 211 GLN GLN A . n 
A 1 216 LEU 216 212 212 LEU LEU A . n 
A 1 217 PHE 217 213 213 PHE PHE A . n 
A 1 218 ARG 218 214 214 ARG ARG A . n 
A 1 219 ILE 219 215 215 ILE ILE A . n 
A 1 220 PHE 220 216 216 PHE PHE A . n 
A 1 221 ARG 221 217 217 ARG ARG A . n 
A 1 222 THR 222 218 218 THR THR A . n 
A 1 223 LEU 223 219 219 LEU LEU A . n 
A 1 224 GLY 224 220 220 GLY GLY A . n 
A 1 225 THR 225 221 221 THR THR A . n 
A 1 226 PRO 226 222 222 PRO PRO A . n 
A 1 227 ASP 227 223 223 ASP ASP A . n 
A 1 228 GLU 228 224 224 GLU GLU A . n 
A 1 229 VAL 229 225 225 VAL VAL A . n 
A 1 230 VAL 230 226 226 VAL VAL A . n 
A 1 231 TRP 231 227 227 TRP TRP A . n 
A 1 232 PRO 232 228 228 PRO PRO A . n 
A 1 233 GLY 233 229 229 GLY GLY A . n 
A 1 234 VAL 234 230 230 VAL VAL A . n 
A 1 235 THR 235 231 231 THR THR A . n 
A 1 236 SER 236 232 232 SER SER A . n 
A 1 237 MET 237 233 233 MET MET A . n 
A 1 238 PRO 238 234 234 PRO PRO A . n 
A 1 239 ASP 239 235 235 ASP ASP A . n 
A 1 240 TYR 240 236 236 TYR TYR A . n 
A 1 241 LYS 241 237 237 LYS LYS A . n 
A 1 242 PRO 242 238 238 PRO PRO A . n 
A 1 243 SER 243 239 239 SER SER A . n 
A 1 244 PHE 244 240 240 PHE PHE A . n 
A 1 245 PRO 245 241 241 PRO PRO A . n 
A 1 246 LYS 246 242 242 LYS LYS A . n 
A 1 247 TRP 247 243 243 TRP TRP A . n 
A 1 248 ALA 248 244 244 ALA ALA A . n 
A 1 249 ARG 249 245 245 ARG ARG A . n 
A 1 250 GLN 250 246 246 GLN GLN A . n 
A 1 251 ASP 251 247 247 ASP ASP A . n 
A 1 252 PHE 252 248 248 PHE PHE A . n 
A 1 253 SER 253 249 249 SER SER A . n 
A 1 254 LYS 254 250 250 LYS LYS A . n 
A 1 255 VAL 255 251 251 VAL VAL A . n 
A 1 256 VAL 256 252 252 VAL VAL A . n 
A 1 257 PRO 257 253 253 PRO PRO A . n 
A 1 258 PRO 258 254 254 PRO PRO A . n 
A 1 259 LEU 259 255 255 LEU LEU A . n 
A 1 260 ASP 260 256 256 ASP ASP A . n 
A 1 261 GLU 261 257 257 GLU GLU A . n 
A 1 262 ASP 262 258 258 ASP ASP A . n 
A 1 263 GLY 263 259 259 GLY GLY A . n 
A 1 264 ARG 264 260 260 ARG ARG A . n 
A 1 265 SER 265 261 261 SER SER A . n 
A 1 266 LEU 266 262 262 LEU LEU A . n 
A 1 267 LEU 267 263 263 LEU LEU A . n 
A 1 268 SER 268 264 264 SER SER A . n 
A 1 269 GLN 269 265 265 GLN GLN A . n 
A 1 270 MET 270 266 266 MET MET A . n 
A 1 271 LEU 271 267 267 LEU LEU A . n 
A 1 272 HIS 272 268 268 HIS HIS A . n 
A 1 273 TYR 273 269 269 TYR TYR A . n 
A 1 274 ASP 274 270 270 ASP ASP A . n 
A 1 275 PRO 275 271 271 PRO PRO A . n 
A 1 276 ASN 276 272 272 ASN ASN A . n 
A 1 277 LYS 277 273 273 LYS LYS A . n 
A 1 278 ARG 278 274 274 ARG ARG A . n 
A 1 279 ILE 279 275 275 ILE ILE A . n 
A 1 280 SER 280 276 276 SER SER A . n 
A 1 281 ALA 281 277 277 ALA ALA A . n 
A 1 282 LYS 282 278 278 LYS LYS A . n 
A 1 283 ALA 283 279 279 ALA ALA A . n 
A 1 284 ALA 284 280 280 ALA ALA A . n 
A 1 285 LEU 285 281 281 LEU LEU A . n 
A 1 286 ALA 286 282 282 ALA ALA A . n 
A 1 287 HIS 287 283 283 HIS HIS A . n 
A 1 288 PRO 288 284 284 PRO PRO A . n 
A 1 289 PHE 289 285 285 PHE PHE A . n 
A 1 290 PHE 290 286 286 PHE PHE A . n 
A 1 291 GLN 291 287 287 GLN GLN A . n 
A 1 292 ASP 292 288 288 ASP ASP A . n 
A 1 293 VAL 293 289 289 VAL VAL A . n 
A 1 294 THR 294 290 ?   ?   ?   A . n 
A 1 295 LYS 295 291 ?   ?   ?   A . n 
A 1 296 PRO 296 292 ?   ?   ?   A . n 
A 1 297 VAL 297 293 ?   ?   ?   A . n 
A 1 298 PRO 298 294 ?   ?   ?   A . n 
A 1 299 HIS 299 295 ?   ?   ?   A . n 
A 1 300 LEU 300 296 ?   ?   ?   A . n 
A 1 301 ARG 301 297 ?   ?   ?   A . n 
A 1 302 LEU 302 298 ?   ?   ?   A . n 
B 2 1   GLY 1   171 171 GLY GLY B . n 
B 2 2   VAL 2   172 172 VAL VAL B . n 
B 2 3   ASN 3   173 173 ASN ASN B . n 
B 2 4   GLU 4   174 174 GLU GLU B . n 
B 2 5   VAL 5   175 175 VAL VAL B . n 
B 2 6   PRO 6   176 176 PRO PRO B . n 
B 2 7   ASP 7   177 177 ASP ASP B . n 
B 2 8   TYR 8   178 178 TYR TYR B . n 
B 2 9   HIS 9   179 179 HIS HIS B . n 
B 2 10  GLU 10  180 180 GLU GLU B . n 
B 2 11  ASP 11  181 181 ASP ASP B . n 
B 2 12  ILE 12  182 182 ILE ILE B . n 
B 2 13  HIS 13  183 183 HIS HIS B . n 
B 2 14  THR 14  184 184 THR THR B . n 
B 2 15  TYR 15  185 185 TYR TYR B . n 
B 2 16  LEU 16  186 186 LEU LEU B . n 
B 2 17  ARG 17  187 187 ARG ARG B . n 
B 2 18  GLU 18  188 188 GLU GLU B . n 
B 2 19  MET 19  189 189 MET MET B . n 
B 2 20  GLU 20  190 190 GLU GLU B . n 
B 2 21  VAL 21  191 191 VAL VAL B . n 
B 2 22  LYS 22  192 192 LYS LYS B . n 
B 2 23  CYS 23  193 193 CYS CYS B . n 
B 2 24  LYS 24  194 194 LYS LYS B . n 
B 2 25  PRO 25  195 195 PRO PRO B . n 
B 2 26  LYS 26  196 196 LYS LYS B . n 
B 2 27  VAL 27  197 197 VAL VAL B . n 
B 2 28  GLY 28  198 198 GLY GLY B . n 
B 2 29  TYR 29  199 199 TYR TYR B . n 
B 2 30  MET 30  200 200 MET MET B . n 
B 2 31  LYS 31  201 201 LYS LYS B . n 
B 2 32  LYS 32  202 202 LYS LYS B . n 
B 2 33  GLN 33  203 203 GLN GLN B . n 
B 2 34  PRO 34  204 204 PRO PRO B . n 
B 2 35  ASP 35  205 205 ASP ASP B . n 
B 2 36  ILE 36  206 206 ILE ILE B . n 
B 2 37  THR 37  207 207 THR THR B . n 
B 2 38  ASN 38  208 208 ASN ASN B . n 
B 2 39  SER 39  209 209 SER SER B . n 
B 2 40  MET 40  210 210 MET MET B . n 
B 2 41  ARG 41  211 211 ARG ARG B . n 
B 2 42  ALA 42  212 212 ALA ALA B . n 
B 2 43  ILE 43  213 213 ILE ILE B . n 
B 2 44  LEU 44  214 214 LEU LEU B . n 
B 2 45  VAL 45  215 215 VAL VAL B . n 
B 2 46  ASP 46  216 216 ASP ASP B . n 
B 2 47  TRP 47  217 217 TRP TRP B . n 
B 2 48  LEU 48  218 218 LEU LEU B . n 
B 2 49  VAL 49  219 219 VAL VAL B . n 
B 2 50  GLU 50  220 220 GLU GLU B . n 
B 2 51  VAL 51  221 221 VAL VAL B . n 
B 2 52  GLY 52  222 222 GLY GLY B . n 
B 2 53  GLU 53  223 223 GLU GLU B . n 
B 2 54  GLU 54  224 224 GLU GLU B . n 
B 2 55  TYR 55  225 225 TYR TYR B . n 
B 2 56  LYS 56  226 226 LYS LYS B . n 
B 2 57  LEU 57  227 227 LEU LEU B . n 
B 2 58  GLN 58  228 228 GLN GLN B . n 
B 2 59  ASN 59  229 229 ASN ASN B . n 
B 2 60  GLU 60  230 230 GLU GLU B . n 
B 2 61  THR 61  231 231 THR THR B . n 
B 2 62  LEU 62  232 232 LEU LEU B . n 
B 2 63  HIS 63  233 233 HIS HIS B . n 
B 2 64  LEU 64  234 234 LEU LEU B . n 
B 2 65  ALA 65  235 235 ALA ALA B . n 
B 2 66  VAL 66  236 236 VAL VAL B . n 
B 2 67  ASN 67  237 237 ASN ASN B . n 
B 2 68  TYR 68  238 238 TYR TYR B . n 
B 2 69  ILE 69  239 239 ILE ILE B . n 
B 2 70  ASP 70  240 240 ASP ASP B . n 
B 2 71  ARG 71  241 241 ARG ARG B . n 
B 2 72  PHE 72  242 242 PHE PHE B . n 
B 2 73  LEU 73  243 243 LEU LEU B . n 
B 2 74  SER 74  244 244 SER SER B . n 
B 2 75  SER 75  245 245 SER SER B . n 
B 2 76  MET 76  246 246 MET MET B . n 
B 2 77  SER 77  247 247 SER SER B . n 
B 2 78  VAL 78  248 248 VAL VAL B . n 
B 2 79  LEU 79  249 249 LEU LEU B . n 
B 2 80  ARG 80  250 250 ARG ARG B . n 
B 2 81  GLY 81  251 251 GLY GLY B . n 
B 2 82  LYS 82  252 252 LYS LYS B . n 
B 2 83  LEU 83  253 253 LEU LEU B . n 
B 2 84  GLN 84  254 254 GLN GLN B . n 
B 2 85  LEU 85  255 255 LEU LEU B . n 
B 2 86  VAL 86  256 256 VAL VAL B . n 
B 2 87  GLY 87  257 257 GLY GLY B . n 
B 2 88  THR 88  258 258 THR THR B . n 
B 2 89  ALA 89  259 259 ALA ALA B . n 
B 2 90  ALA 90  260 260 ALA ALA B . n 
B 2 91  MET 91  261 261 MET MET B . n 
B 2 92  LEU 92  262 262 LEU LEU B . n 
B 2 93  LEU 93  263 263 LEU LEU B . n 
B 2 94  ALA 94  264 264 ALA ALA B . n 
B 2 95  SER 95  265 265 SER SER B . n 
B 2 96  LYS 96  266 266 LYS LYS B . n 
B 2 97  PHE 97  267 267 PHE PHE B . n 
B 2 98  GLU 98  268 268 GLU GLU B . n 
B 2 99  GLU 99  269 269 GLU GLU B . n 
B 2 100 ILE 100 270 270 ILE ILE B . n 
B 2 101 TYR 101 271 271 TYR TYR B . n 
B 2 102 PRO 102 272 272 PRO PRO B . n 
B 2 103 PRO 103 273 273 PRO PRO B . n 
B 2 104 GLU 104 274 274 GLU GLU B . n 
B 2 105 VAL 105 275 275 VAL VAL B . n 
B 2 106 ALA 106 276 276 ALA ALA B . n 
B 2 107 GLU 107 277 277 GLU GLU B . n 
B 2 108 PHE 108 278 278 PHE PHE B . n 
B 2 109 VAL 109 279 279 VAL VAL B . n 
B 2 110 TYR 110 280 280 TYR TYR B . n 
B 2 111 ILE 111 281 281 ILE ILE B . n 
B 2 112 THR 112 282 282 THR THR B . n 
B 2 113 ASP 113 283 283 ASP ASP B . n 
B 2 114 ASP 114 284 284 ASP ASP B . n 
B 2 115 THR 115 285 285 THR THR B . n 
B 2 116 TYR 116 286 286 TYR TYR B . n 
B 2 117 THR 117 287 287 THR THR B . n 
B 2 118 LYS 118 288 288 LYS LYS B . n 
B 2 119 LYS 119 289 289 LYS LYS B . n 
B 2 120 GLN 120 290 290 GLN GLN B . n 
B 2 121 VAL 121 291 291 VAL VAL B . n 
B 2 122 LEU 122 292 292 LEU LEU B . n 
B 2 123 ARG 123 293 293 ARG ARG B . n 
B 2 124 MET 124 294 294 MET MET B . n 
B 2 125 GLU 125 295 295 GLU GLU B . n 
B 2 126 HIS 126 296 296 HIS HIS B . n 
B 2 127 LEU 127 297 297 LEU LEU B . n 
B 2 128 VAL 128 298 298 VAL VAL B . n 
B 2 129 LEU 129 299 299 LEU LEU B . n 
B 2 130 LYS 130 300 300 LYS LYS B . n 
B 2 131 VAL 131 301 301 VAL VAL B . n 
B 2 132 LEU 132 302 302 LEU LEU B . n 
B 2 133 ALA 133 303 303 ALA ALA B . n 
B 2 134 PHE 134 304 304 PHE PHE B . n 
B 2 135 ASP 135 305 305 ASP ASP B . n 
B 2 136 LEU 136 306 306 LEU LEU B . n 
B 2 137 ALA 137 307 307 ALA ALA B . n 
B 2 138 ALA 138 308 308 ALA ALA B . n 
B 2 139 PRO 139 309 309 PRO PRO B . n 
B 2 140 THR 140 310 310 THR THR B . n 
B 2 141 ILE 141 311 311 ILE ILE B . n 
B 2 142 ASN 142 312 312 ASN ASN B . n 
B 2 143 GLN 143 313 313 GLN GLN B . n 
B 2 144 PHE 144 314 314 PHE PHE B . n 
B 2 145 LEU 145 315 315 LEU LEU B . n 
B 2 146 THR 146 316 316 THR THR B . n 
B 2 147 GLN 147 317 317 GLN GLN B . n 
B 2 148 TYR 148 318 318 TYR TYR B . n 
B 2 149 PHE 149 319 319 PHE PHE B . n 
B 2 150 LEU 150 320 320 LEU LEU B . n 
B 2 151 HIS 151 321 321 HIS HIS B . n 
B 2 152 GLN 152 322 322 GLN GLN B . n 
B 2 153 GLN 153 323 323 GLN GLN B . n 
B 2 154 PRO 154 324 324 PRO PRO B . n 
B 2 155 ALA 155 325 325 ALA ALA B . n 
B 2 156 ASN 156 326 326 ASN ASN B . n 
B 2 157 CYS 157 327 327 CYS CYS B . n 
B 2 158 LYS 158 328 328 LYS LYS B . n 
B 2 159 VAL 159 329 329 VAL VAL B . n 
B 2 160 GLU 160 330 330 GLU GLU B . n 
B 2 161 SER 161 331 331 SER SER B . n 
B 2 162 LEU 162 332 332 LEU LEU B . n 
B 2 163 ALA 163 333 333 ALA ALA B . n 
B 2 164 MET 164 334 334 MET MET B . n 
B 2 165 PHE 165 335 335 PHE PHE B . n 
B 2 166 LEU 166 336 336 LEU LEU B . n 
B 2 167 GLY 167 337 337 GLY GLY B . n 
B 2 168 GLU 168 338 338 GLU GLU B . n 
B 2 169 LEU 169 339 339 LEU LEU B . n 
B 2 170 SER 170 340 340 SER SER B . n 
B 2 171 LEU 171 341 341 LEU LEU B . n 
B 2 172 ILE 172 342 342 ILE ILE B . n 
B 2 173 ASP 173 343 343 ASP ASP B . n 
B 2 174 ALA 174 344 344 ALA ALA B . n 
B 2 175 ASP 175 345 345 ASP ASP B . n 
B 2 176 PRO 176 346 346 PRO PRO B . n 
B 2 177 TYR 177 347 347 TYR TYR B . n 
B 2 178 LEU 178 348 348 LEU LEU B . n 
B 2 179 LYS 179 349 349 LYS LYS B . n 
B 2 180 TYR 180 350 350 TYR TYR B . n 
B 2 181 LEU 181 351 351 LEU LEU B . n 
B 2 182 PRO 182 352 352 PRO PRO B . n 
B 2 183 SER 183 353 353 SER SER B . n 
B 2 184 VAL 184 354 354 VAL VAL B . n 
B 2 185 ILE 185 355 355 ILE ILE B . n 
B 2 186 ALA 186 356 356 ALA ALA B . n 
B 2 187 ALA 187 357 357 ALA ALA B . n 
B 2 188 ALA 188 358 358 ALA ALA B . n 
B 2 189 ALA 189 359 359 ALA ALA B . n 
B 2 190 PHE 190 360 360 PHE PHE B . n 
B 2 191 HIS 191 361 361 HIS HIS B . n 
B 2 192 LEU 192 362 362 LEU LEU B . n 
B 2 193 ALA 193 363 363 ALA ALA B . n 
B 2 194 LEU 194 364 364 LEU LEU B . n 
B 2 195 TYR 195 365 365 TYR TYR B . n 
B 2 196 THR 196 366 366 THR THR B . n 
B 2 197 VAL 197 367 367 VAL VAL B . n 
B 2 198 THR 198 368 368 THR THR B . n 
B 2 199 GLY 199 369 369 GLY GLY B . n 
B 2 200 GLN 200 370 370 GLN GLN B . n 
B 2 201 SER 201 371 371 SER SER B . n 
B 2 202 TRP 202 372 372 TRP TRP B . n 
B 2 203 PRO 203 373 373 PRO PRO B . n 
B 2 204 GLU 204 374 374 GLU GLU B . n 
B 2 205 SER 205 375 375 SER SER B . n 
B 2 206 LEU 206 376 376 LEU LEU B . n 
B 2 207 VAL 207 377 377 VAL VAL B . n 
B 2 208 GLN 208 378 378 GLN GLN B . n 
B 2 209 LYS 209 379 379 LYS LYS B . n 
B 2 210 THR 210 380 380 THR THR B . n 
B 2 211 GLY 211 381 381 GLY GLY B . n 
B 2 212 TYR 212 382 382 TYR TYR B . n 
B 2 213 THR 213 383 383 THR THR B . n 
B 2 214 LEU 214 384 384 LEU LEU B . n 
B 2 215 GLU 215 385 385 GLU GLU B . n 
B 2 216 THR 216 386 386 THR THR B . n 
B 2 217 LEU 217 387 387 LEU LEU B . n 
B 2 218 LYS 218 388 388 LYS LYS B . n 
B 2 219 PRO 219 389 389 PRO PRO B . n 
B 2 220 CYS 220 390 390 CYS CYS B . n 
B 2 221 LEU 221 391 391 LEU LEU B . n 
B 2 222 LEU 222 392 392 LEU LEU B . n 
B 2 223 ASP 223 393 393 ASP ASP B . n 
B 2 224 LEU 224 394 394 LEU LEU B . n 
B 2 225 HIS 225 395 395 HIS HIS B . n 
B 2 226 GLN 226 396 396 GLN GLN B . n 
B 2 227 THR 227 397 397 THR THR B . n 
B 2 228 TYR 228 398 398 TYR TYR B . n 
B 2 229 LEU 229 399 399 LEU LEU B . n 
B 2 230 ARG 230 400 400 ARG ARG B . n 
B 2 231 ALA 231 401 401 ALA ALA B . n 
B 2 232 PRO 232 402 402 PRO PRO B . n 
B 2 233 GLN 233 403 403 GLN GLN B . n 
B 2 234 HIS 234 404 404 HIS HIS B . n 
B 2 235 ALA 235 405 405 ALA ALA B . n 
B 2 236 GLN 236 406 406 GLN GLN B . n 
B 2 237 GLN 237 407 407 GLN GLN B . n 
B 2 238 SER 238 408 408 SER SER B . n 
B 2 239 ILE 239 409 409 ILE ILE B . n 
B 2 240 ARG 240 410 410 ARG ARG B . n 
B 2 241 GLU 241 411 411 GLU GLU B . n 
B 2 242 LYS 242 412 412 LYS LYS B . n 
B 2 243 TYR 243 413 413 TYR TYR B . n 
B 2 244 LYS 244 414 414 LYS LYS B . n 
B 2 245 ASN 245 415 415 ASN ASN B . n 
B 2 246 SER 246 416 416 SER SER B . n 
B 2 247 LYS 247 417 417 LYS LYS B . n 
B 2 248 TYR 248 418 418 TYR TYR B . n 
B 2 249 HIS 249 419 419 HIS HIS B . n 
B 2 250 GLY 250 420 420 GLY GLY B . n 
B 2 251 VAL 251 421 421 VAL VAL B . n 
B 2 252 SER 252 422 422 SER SER B . n 
B 2 253 LEU 253 423 423 LEU LEU B . n 
B 2 254 LEU 254 424 424 LEU LEU B . n 
B 2 255 ASN 255 425 425 ASN ASN B . n 
B 2 256 PRO 256 426 426 PRO PRO B . n 
B 2 257 PRO 257 427 427 PRO PRO B . n 
B 2 258 GLU 258 428 428 GLU GLU B . n 
B 2 259 THR 259 429 429 THR THR B . n 
B 2 260 LEU 260 430 430 LEU LEU B . n 
B 2 261 ASN 261 431 431 ASN ASN B . n 
B 2 262 VAL 262 432 432 VAL VAL B . n 
B 2 263 HIS 263 433 ?   ?   ?   B . n 
B 2 264 HIS 264 434 ?   ?   ?   B . n 
B 2 265 HIS 265 435 ?   ?   ?   B . n 
B 2 266 HIS 266 436 ?   ?   ?   B . n 
B 2 267 HIS 267 437 ?   ?   ?   B . n 
B 2 268 HIS 268 438 ?   ?   ?   B . n 
C 1 1   GLY 1   -3  ?   ?   ?   C . n 
C 1 2   PRO 2   -2  ?   ?   ?   C . n 
C 1 3   GLY 3   -1  ?   ?   ?   C . n 
C 1 4   SER 4   0   0   SER SER C . n 
C 1 5   MET 5   1   1   MET MET C . n 
C 1 6   GLU 6   2   2   GLU GLU C . n 
C 1 7   ASN 7   3   3   ASN ASN C . n 
C 1 8   PHE 8   4   4   PHE PHE C . n 
C 1 9   GLN 9   5   5   GLN GLN C . n 
C 1 10  LYS 10  6   6   LYS LYS C . n 
C 1 11  VAL 11  7   7   VAL VAL C . n 
C 1 12  GLU 12  8   8   GLU GLU C . n 
C 1 13  LYS 13  9   9   LYS LYS C . n 
C 1 14  ILE 14  10  10  ILE ILE C . n 
C 1 15  GLY 15  11  11  GLY GLY C . n 
C 1 16  GLU 16  12  12  GLU GLU C . n 
C 1 17  GLY 17  13  13  GLY GLY C . n 
C 1 18  THR 18  14  14  THR THR C . n 
C 1 19  TYR 19  15  15  TYR TYR C . n 
C 1 20  GLY 20  16  16  GLY GLY C . n 
C 1 21  VAL 21  17  17  VAL VAL C . n 
C 1 22  VAL 22  18  18  VAL VAL C . n 
C 1 23  TYR 23  19  19  TYR TYR C . n 
C 1 24  LYS 24  20  20  LYS LYS C . n 
C 1 25  ALA 25  21  21  ALA ALA C . n 
C 1 26  ARG 26  22  22  ARG ARG C . n 
C 1 27  ASN 27  23  23  ASN ASN C . n 
C 1 28  LYS 28  24  24  LYS LYS C . n 
C 1 29  LEU 29  25  25  LEU LEU C . n 
C 1 30  THR 30  26  26  THR THR C . n 
C 1 31  GLY 31  27  27  GLY GLY C . n 
C 1 32  GLU 32  28  28  GLU GLU C . n 
C 1 33  VAL 33  29  29  VAL VAL C . n 
C 1 34  VAL 34  30  30  VAL VAL C . n 
C 1 35  ALA 35  31  31  ALA ALA C . n 
C 1 36  LEU 36  32  32  LEU LEU C . n 
C 1 37  LYS 37  33  33  LYS LYS C . n 
C 1 38  LYS 38  34  34  LYS LYS C . n 
C 1 39  ILE 39  35  35  ILE ILE C . n 
C 1 40  ARG 40  36  36  ARG ARG C . n 
C 1 41  LEU 41  37  37  LEU LEU C . n 
C 1 42  ASP 42  38  38  ASP ASP C . n 
C 1 43  THR 43  39  39  THR THR C . n 
C 1 44  GLU 44  40  40  GLU GLU C . n 
C 1 45  THR 45  41  41  THR THR C . n 
C 1 46  GLU 46  42  42  GLU GLU C . n 
C 1 47  GLY 47  43  43  GLY GLY C . n 
C 1 48  VAL 48  44  44  VAL VAL C . n 
C 1 49  PRO 49  45  45  PRO PRO C . n 
C 1 50  SER 50  46  46  SER SER C . n 
C 1 51  THR 51  47  47  THR THR C . n 
C 1 52  ALA 52  48  48  ALA ALA C . n 
C 1 53  ILE 53  49  49  ILE ILE C . n 
C 1 54  ARG 54  50  50  ARG ARG C . n 
C 1 55  GLU 55  51  51  GLU GLU C . n 
C 1 56  ILE 56  52  52  ILE ILE C . n 
C 1 57  SER 57  53  53  SER SER C . n 
C 1 58  LEU 58  54  54  LEU LEU C . n 
C 1 59  LEU 59  55  55  LEU LEU C . n 
C 1 60  LYS 60  56  56  LYS LYS C . n 
C 1 61  GLU 61  57  57  GLU GLU C . n 
C 1 62  LEU 62  58  58  LEU LEU C . n 
C 1 63  ASN 63  59  59  ASN ASN C . n 
C 1 64  HIS 64  60  60  HIS HIS C . n 
C 1 65  PRO 65  61  61  PRO PRO C . n 
C 1 66  ASN 66  62  62  ASN ASN C . n 
C 1 67  ILE 67  63  63  ILE ILE C . n 
C 1 68  VAL 68  64  64  VAL VAL C . n 
C 1 69  LYS 69  65  65  LYS LYS C . n 
C 1 70  LEU 70  66  66  LEU LEU C . n 
C 1 71  LEU 71  67  67  LEU LEU C . n 
C 1 72  ASP 72  68  68  ASP ASP C . n 
C 1 73  VAL 73  69  69  VAL VAL C . n 
C 1 74  ILE 74  70  70  ILE ILE C . n 
C 1 75  HIS 75  71  71  HIS HIS C . n 
C 1 76  THR 76  72  72  THR THR C . n 
C 1 77  GLU 77  73  73  GLU GLU C . n 
C 1 78  ASN 78  74  74  ASN ASN C . n 
C 1 79  LYS 79  75  75  LYS LYS C . n 
C 1 80  LEU 80  76  76  LEU LEU C . n 
C 1 81  TYR 81  77  77  TYR TYR C . n 
C 1 82  LEU 82  78  78  LEU LEU C . n 
C 1 83  VAL 83  79  79  VAL VAL C . n 
C 1 84  PHE 84  80  80  PHE PHE C . n 
C 1 85  GLU 85  81  81  GLU GLU C . n 
C 1 86  PHE 86  82  82  PHE PHE C . n 
C 1 87  LEU 87  83  83  LEU LEU C . n 
C 1 88  HIS 88  84  84  HIS HIS C . n 
C 1 89  GLN 89  85  85  GLN GLN C . n 
C 1 90  ASP 90  86  86  ASP ASP C . n 
C 1 91  LEU 91  87  87  LEU LEU C . n 
C 1 92  LYS 92  88  88  LYS LYS C . n 
C 1 93  LYS 93  89  89  LYS LYS C . n 
C 1 94  PHE 94  90  90  PHE PHE C . n 
C 1 95  MET 95  91  91  MET MET C . n 
C 1 96  ASP 96  92  92  ASP ASP C . n 
C 1 97  ALA 97  93  93  ALA ALA C . n 
C 1 98  SER 98  94  94  SER SER C . n 
C 1 99  ALA 99  95  95  ALA ALA C . n 
C 1 100 LEU 100 96  96  LEU LEU C . n 
C 1 101 THR 101 97  97  THR THR C . n 
C 1 102 GLY 102 98  98  GLY GLY C . n 
C 1 103 ILE 103 99  99  ILE ILE C . n 
C 1 104 PRO 104 100 100 PRO PRO C . n 
C 1 105 LEU 105 101 101 LEU LEU C . n 
C 1 106 PRO 106 102 102 PRO PRO C . n 
C 1 107 LEU 107 103 103 LEU LEU C . n 
C 1 108 ILE 108 104 104 ILE ILE C . n 
C 1 109 LYS 109 105 105 LYS LYS C . n 
C 1 110 SER 110 106 106 SER SER C . n 
C 1 111 TYR 111 107 107 TYR TYR C . n 
C 1 112 LEU 112 108 108 LEU LEU C . n 
C 1 113 PHE 113 109 109 PHE PHE C . n 
C 1 114 GLN 114 110 110 GLN GLN C . n 
C 1 115 LEU 115 111 111 LEU LEU C . n 
C 1 116 LEU 116 112 112 LEU LEU C . n 
C 1 117 GLN 117 113 113 GLN GLN C . n 
C 1 118 GLY 118 114 114 GLY GLY C . n 
C 1 119 LEU 119 115 115 LEU LEU C . n 
C 1 120 ALA 120 116 116 ALA ALA C . n 
C 1 121 PHE 121 117 117 PHE PHE C . n 
C 1 122 CYS 122 118 118 CYS CYS C . n 
C 1 123 HIS 123 119 119 HIS HIS C . n 
C 1 124 SER 124 120 120 SER SER C . n 
C 1 125 HIS 125 121 121 HIS HIS C . n 
C 1 126 ARG 126 122 122 ARG ARG C . n 
C 1 127 VAL 127 123 123 VAL VAL C . n 
C 1 128 LEU 128 124 124 LEU LEU C . n 
C 1 129 HIS 129 125 125 HIS HIS C . n 
C 1 130 ARG 130 126 126 ARG ARG C . n 
C 1 131 ASP 131 127 127 ASP ASP C . n 
C 1 132 LEU 132 128 128 LEU LEU C . n 
C 1 133 LYS 133 129 129 LYS LYS C . n 
C 1 134 PRO 134 130 130 PRO PRO C . n 
C 1 135 GLN 135 131 131 GLN GLN C . n 
C 1 136 ASN 136 132 132 ASN ASN C . n 
C 1 137 LEU 137 133 133 LEU LEU C . n 
C 1 138 LEU 138 134 134 LEU LEU C . n 
C 1 139 ILE 139 135 135 ILE ILE C . n 
C 1 140 ASN 140 136 136 ASN ASN C . n 
C 1 141 THR 141 137 137 THR THR C . n 
C 1 142 GLU 142 138 138 GLU GLU C . n 
C 1 143 GLY 143 139 139 GLY GLY C . n 
C 1 144 ALA 144 140 140 ALA ALA C . n 
C 1 145 ILE 145 141 141 ILE ILE C . n 
C 1 146 LYS 146 142 142 LYS LYS C . n 
C 1 147 LEU 147 143 143 LEU LEU C . n 
C 1 148 ALA 148 144 144 ALA ALA C . n 
C 1 149 ASP 149 145 145 ASP ASP C . n 
C 1 150 PHE 150 146 146 PHE PHE C . n 
C 1 151 GLY 151 147 147 GLY GLY C . n 
C 1 152 LEU 152 148 148 LEU LEU C . n 
C 1 153 ALA 153 149 149 ALA ALA C . n 
C 1 154 ARG 154 150 150 ARG ARG C . n 
C 1 155 ALA 155 151 151 ALA ALA C . n 
C 1 156 PHE 156 152 152 PHE PHE C . n 
C 1 157 GLY 157 153 153 GLY GLY C . n 
C 1 158 VAL 158 154 154 VAL VAL C . n 
C 1 159 PRO 159 155 155 PRO PRO C . n 
C 1 160 VAL 160 156 156 VAL VAL C . n 
C 1 161 ARG 161 157 157 ARG ARG C . n 
C 1 162 THR 162 158 158 THR THR C . n 
C 1 163 TYR 163 159 159 TYR TYR C . n 
C 1 164 TPO 164 160 160 TPO TPO C . n 
C 1 165 HIS 165 161 161 HIS HIS C . n 
C 1 166 GLU 166 162 162 GLU GLU C . n 
C 1 167 VAL 167 163 163 VAL VAL C . n 
C 1 168 VAL 168 164 164 VAL VAL C . n 
C 1 169 THR 169 165 165 THR THR C . n 
C 1 170 LEU 170 166 166 LEU LEU C . n 
C 1 171 TRP 171 167 167 TRP TRP C . n 
C 1 172 TYR 172 168 168 TYR TYR C . n 
C 1 173 ARG 173 169 169 ARG ARG C . n 
C 1 174 ALA 174 170 170 ALA ALA C . n 
C 1 175 PRO 175 171 171 PRO PRO C . n 
C 1 176 GLU 176 172 172 GLU GLU C . n 
C 1 177 ILE 177 173 173 ILE ILE C . n 
C 1 178 LEU 178 174 174 LEU LEU C . n 
C 1 179 LEU 179 175 175 LEU LEU C . n 
C 1 180 GLY 180 176 176 GLY GLY C . n 
C 1 181 CYS 181 177 177 CYS CYS C . n 
C 1 182 LYS 182 178 178 LYS LYS C . n 
C 1 183 TYR 183 179 179 TYR TYR C . n 
C 1 184 TYR 184 180 180 TYR TYR C . n 
C 1 185 SER 185 181 181 SER SER C . n 
C 1 186 THR 186 182 182 THR THR C . n 
C 1 187 ALA 187 183 183 ALA ALA C . n 
C 1 188 VAL 188 184 184 VAL VAL C . n 
C 1 189 ASP 189 185 185 ASP ASP C . n 
C 1 190 ILE 190 186 186 ILE ILE C . n 
C 1 191 TRP 191 187 187 TRP TRP C . n 
C 1 192 SER 192 188 188 SER SER C . n 
C 1 193 LEU 193 189 189 LEU LEU C . n 
C 1 194 GLY 194 190 190 GLY GLY C . n 
C 1 195 CYS 195 191 191 CYS CYS C . n 
C 1 196 ILE 196 192 192 ILE ILE C . n 
C 1 197 PHE 197 193 193 PHE PHE C . n 
C 1 198 ALA 198 194 194 ALA ALA C . n 
C 1 199 GLU 199 195 195 GLU GLU C . n 
C 1 200 MET 200 196 196 MET MET C . n 
C 1 201 VAL 201 197 197 VAL VAL C . n 
C 1 202 THR 202 198 198 THR THR C . n 
C 1 203 ARG 203 199 199 ARG ARG C . n 
C 1 204 ARG 204 200 200 ARG ARG C . n 
C 1 205 ALA 205 201 201 ALA ALA C . n 
C 1 206 LEU 206 202 202 LEU LEU C . n 
C 1 207 PHE 207 203 203 PHE PHE C . n 
C 1 208 PRO 208 204 204 PRO PRO C . n 
C 1 209 GLY 209 205 205 GLY GLY C . n 
C 1 210 ASP 210 206 206 ASP ASP C . n 
C 1 211 SER 211 207 207 SER SER C . n 
C 1 212 GLU 212 208 208 GLU GLU C . n 
C 1 213 ILE 213 209 209 ILE ILE C . n 
C 1 214 ASP 214 210 210 ASP ASP C . n 
C 1 215 GLN 215 211 211 GLN GLN C . n 
C 1 216 LEU 216 212 212 LEU LEU C . n 
C 1 217 PHE 217 213 213 PHE PHE C . n 
C 1 218 ARG 218 214 214 ARG ARG C . n 
C 1 219 ILE 219 215 215 ILE ILE C . n 
C 1 220 PHE 220 216 216 PHE PHE C . n 
C 1 221 ARG 221 217 217 ARG ARG C . n 
C 1 222 THR 222 218 218 THR THR C . n 
C 1 223 LEU 223 219 219 LEU LEU C . n 
C 1 224 GLY 224 220 220 GLY GLY C . n 
C 1 225 THR 225 221 221 THR THR C . n 
C 1 226 PRO 226 222 222 PRO PRO C . n 
C 1 227 ASP 227 223 223 ASP ASP C . n 
C 1 228 GLU 228 224 224 GLU GLU C . n 
C 1 229 VAL 229 225 225 VAL VAL C . n 
C 1 230 VAL 230 226 226 VAL VAL C . n 
C 1 231 TRP 231 227 227 TRP TRP C . n 
C 1 232 PRO 232 228 228 PRO PRO C . n 
C 1 233 GLY 233 229 229 GLY GLY C . n 
C 1 234 VAL 234 230 230 VAL VAL C . n 
C 1 235 THR 235 231 231 THR THR C . n 
C 1 236 SER 236 232 232 SER SER C . n 
C 1 237 MET 237 233 233 MET MET C . n 
C 1 238 PRO 238 234 234 PRO PRO C . n 
C 1 239 ASP 239 235 235 ASP ASP C . n 
C 1 240 TYR 240 236 236 TYR TYR C . n 
C 1 241 LYS 241 237 237 LYS LYS C . n 
C 1 242 PRO 242 238 238 PRO PRO C . n 
C 1 243 SER 243 239 239 SER SER C . n 
C 1 244 PHE 244 240 240 PHE PHE C . n 
C 1 245 PRO 245 241 241 PRO PRO C . n 
C 1 246 LYS 246 242 242 LYS LYS C . n 
C 1 247 TRP 247 243 243 TRP TRP C . n 
C 1 248 ALA 248 244 244 ALA ALA C . n 
C 1 249 ARG 249 245 245 ARG ARG C . n 
C 1 250 GLN 250 246 246 GLN GLN C . n 
C 1 251 ASP 251 247 247 ASP ASP C . n 
C 1 252 PHE 252 248 248 PHE PHE C . n 
C 1 253 SER 253 249 249 SER SER C . n 
C 1 254 LYS 254 250 250 LYS LYS C . n 
C 1 255 VAL 255 251 251 VAL VAL C . n 
C 1 256 VAL 256 252 252 VAL VAL C . n 
C 1 257 PRO 257 253 253 PRO PRO C . n 
C 1 258 PRO 258 254 254 PRO PRO C . n 
C 1 259 LEU 259 255 255 LEU LEU C . n 
C 1 260 ASP 260 256 256 ASP ASP C . n 
C 1 261 GLU 261 257 257 GLU GLU C . n 
C 1 262 ASP 262 258 258 ASP ASP C . n 
C 1 263 GLY 263 259 259 GLY GLY C . n 
C 1 264 ARG 264 260 260 ARG ARG C . n 
C 1 265 SER 265 261 261 SER SER C . n 
C 1 266 LEU 266 262 262 LEU LEU C . n 
C 1 267 LEU 267 263 263 LEU LEU C . n 
C 1 268 SER 268 264 264 SER SER C . n 
C 1 269 GLN 269 265 265 GLN GLN C . n 
C 1 270 MET 270 266 266 MET MET C . n 
C 1 271 LEU 271 267 267 LEU LEU C . n 
C 1 272 HIS 272 268 268 HIS HIS C . n 
C 1 273 TYR 273 269 269 TYR TYR C . n 
C 1 274 ASP 274 270 270 ASP ASP C . n 
C 1 275 PRO 275 271 271 PRO PRO C . n 
C 1 276 ASN 276 272 272 ASN ASN C . n 
C 1 277 LYS 277 273 273 LYS LYS C . n 
C 1 278 ARG 278 274 274 ARG ARG C . n 
C 1 279 ILE 279 275 275 ILE ILE C . n 
C 1 280 SER 280 276 276 SER SER C . n 
C 1 281 ALA 281 277 277 ALA ALA C . n 
C 1 282 LYS 282 278 278 LYS LYS C . n 
C 1 283 ALA 283 279 279 ALA ALA C . n 
C 1 284 ALA 284 280 280 ALA ALA C . n 
C 1 285 LEU 285 281 281 LEU LEU C . n 
C 1 286 ALA 286 282 282 ALA ALA C . n 
C 1 287 HIS 287 283 283 HIS HIS C . n 
C 1 288 PRO 288 284 284 PRO PRO C . n 
C 1 289 PHE 289 285 285 PHE PHE C . n 
C 1 290 PHE 290 286 286 PHE PHE C . n 
C 1 291 GLN 291 287 287 GLN GLN C . n 
C 1 292 ASP 292 288 288 ASP ASP C . n 
C 1 293 VAL 293 289 289 VAL VAL C . n 
C 1 294 THR 294 290 290 THR THR C . n 
C 1 295 LYS 295 291 291 LYS LYS C . n 
C 1 296 PRO 296 292 292 PRO PRO C . n 
C 1 297 VAL 297 293 293 VAL VAL C . n 
C 1 298 PRO 298 294 294 PRO PRO C . n 
C 1 299 HIS 299 295 295 HIS HIS C . n 
C 1 300 LEU 300 296 296 LEU LEU C . n 
C 1 301 ARG 301 297 ?   ?   ?   C . n 
C 1 302 LEU 302 298 ?   ?   ?   C . n 
D 2 1   GLY 1   171 171 GLY GLY D . n 
D 2 2   VAL 2   172 172 VAL VAL D . n 
D 2 3   ASN 3   173 173 ASN ASN D . n 
D 2 4   GLU 4   174 174 GLU GLU D . n 
D 2 5   VAL 5   175 175 VAL VAL D . n 
D 2 6   PRO 6   176 176 PRO PRO D . n 
D 2 7   ASP 7   177 177 ASP ASP D . n 
D 2 8   TYR 8   178 178 TYR TYR D . n 
D 2 9   HIS 9   179 179 HIS HIS D . n 
D 2 10  GLU 10  180 180 GLU GLU D . n 
D 2 11  ASP 11  181 181 ASP ASP D . n 
D 2 12  ILE 12  182 182 ILE ILE D . n 
D 2 13  HIS 13  183 183 HIS HIS D . n 
D 2 14  THR 14  184 184 THR THR D . n 
D 2 15  TYR 15  185 185 TYR TYR D . n 
D 2 16  LEU 16  186 186 LEU LEU D . n 
D 2 17  ARG 17  187 187 ARG ARG D . n 
D 2 18  GLU 18  188 188 GLU GLU D . n 
D 2 19  MET 19  189 189 MET MET D . n 
D 2 20  GLU 20  190 190 GLU GLU D . n 
D 2 21  VAL 21  191 191 VAL VAL D . n 
D 2 22  LYS 22  192 192 LYS LYS D . n 
D 2 23  CYS 23  193 193 CYS CYS D . n 
D 2 24  LYS 24  194 194 LYS LYS D . n 
D 2 25  PRO 25  195 195 PRO PRO D . n 
D 2 26  LYS 26  196 196 LYS LYS D . n 
D 2 27  VAL 27  197 197 VAL VAL D . n 
D 2 28  GLY 28  198 198 GLY GLY D . n 
D 2 29  TYR 29  199 199 TYR TYR D . n 
D 2 30  MET 30  200 200 MET MET D . n 
D 2 31  LYS 31  201 201 LYS LYS D . n 
D 2 32  LYS 32  202 202 LYS LYS D . n 
D 2 33  GLN 33  203 203 GLN GLN D . n 
D 2 34  PRO 34  204 204 PRO PRO D . n 
D 2 35  ASP 35  205 205 ASP ASP D . n 
D 2 36  ILE 36  206 206 ILE ILE D . n 
D 2 37  THR 37  207 207 THR THR D . n 
D 2 38  ASN 38  208 208 ASN ASN D . n 
D 2 39  SER 39  209 209 SER SER D . n 
D 2 40  MET 40  210 210 MET MET D . n 
D 2 41  ARG 41  211 211 ARG ARG D . n 
D 2 42  ALA 42  212 212 ALA ALA D . n 
D 2 43  ILE 43  213 213 ILE ILE D . n 
D 2 44  LEU 44  214 214 LEU LEU D . n 
D 2 45  VAL 45  215 215 VAL VAL D . n 
D 2 46  ASP 46  216 216 ASP ASP D . n 
D 2 47  TRP 47  217 217 TRP TRP D . n 
D 2 48  LEU 48  218 218 LEU LEU D . n 
D 2 49  VAL 49  219 219 VAL VAL D . n 
D 2 50  GLU 50  220 220 GLU GLU D . n 
D 2 51  VAL 51  221 221 VAL VAL D . n 
D 2 52  GLY 52  222 222 GLY GLY D . n 
D 2 53  GLU 53  223 223 GLU GLU D . n 
D 2 54  GLU 54  224 224 GLU GLU D . n 
D 2 55  TYR 55  225 225 TYR TYR D . n 
D 2 56  LYS 56  226 226 LYS LYS D . n 
D 2 57  LEU 57  227 227 LEU LEU D . n 
D 2 58  GLN 58  228 228 GLN GLN D . n 
D 2 59  ASN 59  229 229 ASN ASN D . n 
D 2 60  GLU 60  230 230 GLU GLU D . n 
D 2 61  THR 61  231 231 THR THR D . n 
D 2 62  LEU 62  232 232 LEU LEU D . n 
D 2 63  HIS 63  233 233 HIS HIS D . n 
D 2 64  LEU 64  234 234 LEU LEU D . n 
D 2 65  ALA 65  235 235 ALA ALA D . n 
D 2 66  VAL 66  236 236 VAL VAL D . n 
D 2 67  ASN 67  237 237 ASN ASN D . n 
D 2 68  TYR 68  238 238 TYR TYR D . n 
D 2 69  ILE 69  239 239 ILE ILE D . n 
D 2 70  ASP 70  240 240 ASP ASP D . n 
D 2 71  ARG 71  241 241 ARG ARG D . n 
D 2 72  PHE 72  242 242 PHE PHE D . n 
D 2 73  LEU 73  243 243 LEU LEU D . n 
D 2 74  SER 74  244 244 SER SER D . n 
D 2 75  SER 75  245 245 SER SER D . n 
D 2 76  MET 76  246 246 MET MET D . n 
D 2 77  SER 77  247 247 SER SER D . n 
D 2 78  VAL 78  248 248 VAL VAL D . n 
D 2 79  LEU 79  249 249 LEU LEU D . n 
D 2 80  ARG 80  250 250 ARG ARG D . n 
D 2 81  GLY 81  251 251 GLY GLY D . n 
D 2 82  LYS 82  252 252 LYS LYS D . n 
D 2 83  LEU 83  253 253 LEU LEU D . n 
D 2 84  GLN 84  254 254 GLN GLN D . n 
D 2 85  LEU 85  255 255 LEU LEU D . n 
D 2 86  VAL 86  256 256 VAL VAL D . n 
D 2 87  GLY 87  257 257 GLY GLY D . n 
D 2 88  THR 88  258 258 THR THR D . n 
D 2 89  ALA 89  259 259 ALA ALA D . n 
D 2 90  ALA 90  260 260 ALA ALA D . n 
D 2 91  MET 91  261 261 MET MET D . n 
D 2 92  LEU 92  262 262 LEU LEU D . n 
D 2 93  LEU 93  263 263 LEU LEU D . n 
D 2 94  ALA 94  264 264 ALA ALA D . n 
D 2 95  SER 95  265 265 SER SER D . n 
D 2 96  LYS 96  266 266 LYS LYS D . n 
D 2 97  PHE 97  267 267 PHE PHE D . n 
D 2 98  GLU 98  268 268 GLU GLU D . n 
D 2 99  GLU 99  269 269 GLU GLU D . n 
D 2 100 ILE 100 270 270 ILE ILE D . n 
D 2 101 TYR 101 271 271 TYR TYR D . n 
D 2 102 PRO 102 272 272 PRO PRO D . n 
D 2 103 PRO 103 273 273 PRO PRO D . n 
D 2 104 GLU 104 274 274 GLU GLU D . n 
D 2 105 VAL 105 275 275 VAL VAL D . n 
D 2 106 ALA 106 276 276 ALA ALA D . n 
D 2 107 GLU 107 277 277 GLU GLU D . n 
D 2 108 PHE 108 278 278 PHE PHE D . n 
D 2 109 VAL 109 279 279 VAL VAL D . n 
D 2 110 TYR 110 280 280 TYR TYR D . n 
D 2 111 ILE 111 281 281 ILE ILE D . n 
D 2 112 THR 112 282 282 THR THR D . n 
D 2 113 ASP 113 283 283 ASP ASP D . n 
D 2 114 ASP 114 284 284 ASP ASP D . n 
D 2 115 THR 115 285 285 THR THR D . n 
D 2 116 TYR 116 286 286 TYR TYR D . n 
D 2 117 THR 117 287 287 THR THR D . n 
D 2 118 LYS 118 288 288 LYS LYS D . n 
D 2 119 LYS 119 289 289 LYS LYS D . n 
D 2 120 GLN 120 290 290 GLN GLN D . n 
D 2 121 VAL 121 291 291 VAL VAL D . n 
D 2 122 LEU 122 292 292 LEU LEU D . n 
D 2 123 ARG 123 293 293 ARG ARG D . n 
D 2 124 MET 124 294 294 MET MET D . n 
D 2 125 GLU 125 295 295 GLU GLU D . n 
D 2 126 HIS 126 296 296 HIS HIS D . n 
D 2 127 LEU 127 297 297 LEU LEU D . n 
D 2 128 VAL 128 298 298 VAL VAL D . n 
D 2 129 LEU 129 299 299 LEU LEU D . n 
D 2 130 LYS 130 300 300 LYS LYS D . n 
D 2 131 VAL 131 301 301 VAL VAL D . n 
D 2 132 LEU 132 302 302 LEU LEU D . n 
D 2 133 ALA 133 303 303 ALA ALA D . n 
D 2 134 PHE 134 304 304 PHE PHE D . n 
D 2 135 ASP 135 305 305 ASP ASP D . n 
D 2 136 LEU 136 306 306 LEU LEU D . n 
D 2 137 ALA 137 307 307 ALA ALA D . n 
D 2 138 ALA 138 308 308 ALA ALA D . n 
D 2 139 PRO 139 309 309 PRO PRO D . n 
D 2 140 THR 140 310 310 THR THR D . n 
D 2 141 ILE 141 311 311 ILE ILE D . n 
D 2 142 ASN 142 312 312 ASN ASN D . n 
D 2 143 GLN 143 313 313 GLN GLN D . n 
D 2 144 PHE 144 314 314 PHE PHE D . n 
D 2 145 LEU 145 315 315 LEU LEU D . n 
D 2 146 THR 146 316 316 THR THR D . n 
D 2 147 GLN 147 317 317 GLN GLN D . n 
D 2 148 TYR 148 318 318 TYR TYR D . n 
D 2 149 PHE 149 319 319 PHE PHE D . n 
D 2 150 LEU 150 320 320 LEU LEU D . n 
D 2 151 HIS 151 321 321 HIS HIS D . n 
D 2 152 GLN 152 322 322 GLN GLN D . n 
D 2 153 GLN 153 323 323 GLN GLN D . n 
D 2 154 PRO 154 324 324 PRO PRO D . n 
D 2 155 ALA 155 325 325 ALA ALA D . n 
D 2 156 ASN 156 326 326 ASN ASN D . n 
D 2 157 CYS 157 327 327 CYS CYS D . n 
D 2 158 LYS 158 328 328 LYS LYS D . n 
D 2 159 VAL 159 329 329 VAL VAL D . n 
D 2 160 GLU 160 330 330 GLU GLU D . n 
D 2 161 SER 161 331 331 SER SER D . n 
D 2 162 LEU 162 332 332 LEU LEU D . n 
D 2 163 ALA 163 333 333 ALA ALA D . n 
D 2 164 MET 164 334 334 MET MET D . n 
D 2 165 PHE 165 335 335 PHE PHE D . n 
D 2 166 LEU 166 336 336 LEU LEU D . n 
D 2 167 GLY 167 337 337 GLY GLY D . n 
D 2 168 GLU 168 338 338 GLU GLU D . n 
D 2 169 LEU 169 339 339 LEU LEU D . n 
D 2 170 SER 170 340 340 SER SER D . n 
D 2 171 LEU 171 341 341 LEU LEU D . n 
D 2 172 ILE 172 342 342 ILE ILE D . n 
D 2 173 ASP 173 343 343 ASP ASP D . n 
D 2 174 ALA 174 344 344 ALA ALA D . n 
D 2 175 ASP 175 345 345 ASP ASP D . n 
D 2 176 PRO 176 346 346 PRO PRO D . n 
D 2 177 TYR 177 347 347 TYR TYR D . n 
D 2 178 LEU 178 348 348 LEU LEU D . n 
D 2 179 LYS 179 349 349 LYS LYS D . n 
D 2 180 TYR 180 350 350 TYR TYR D . n 
D 2 181 LEU 181 351 351 LEU LEU D . n 
D 2 182 PRO 182 352 352 PRO PRO D . n 
D 2 183 SER 183 353 353 SER SER D . n 
D 2 184 VAL 184 354 354 VAL VAL D . n 
D 2 185 ILE 185 355 355 ILE ILE D . n 
D 2 186 ALA 186 356 356 ALA ALA D . n 
D 2 187 ALA 187 357 357 ALA ALA D . n 
D 2 188 ALA 188 358 358 ALA ALA D . n 
D 2 189 ALA 189 359 359 ALA ALA D . n 
D 2 190 PHE 190 360 360 PHE PHE D . n 
D 2 191 HIS 191 361 361 HIS HIS D . n 
D 2 192 LEU 192 362 362 LEU LEU D . n 
D 2 193 ALA 193 363 363 ALA ALA D . n 
D 2 194 LEU 194 364 364 LEU LEU D . n 
D 2 195 TYR 195 365 365 TYR TYR D . n 
D 2 196 THR 196 366 366 THR THR D . n 
D 2 197 VAL 197 367 367 VAL VAL D . n 
D 2 198 THR 198 368 368 THR THR D . n 
D 2 199 GLY 199 369 369 GLY GLY D . n 
D 2 200 GLN 200 370 370 GLN GLN D . n 
D 2 201 SER 201 371 371 SER SER D . n 
D 2 202 TRP 202 372 372 TRP TRP D . n 
D 2 203 PRO 203 373 373 PRO PRO D . n 
D 2 204 GLU 204 374 374 GLU GLU D . n 
D 2 205 SER 205 375 375 SER SER D . n 
D 2 206 LEU 206 376 376 LEU LEU D . n 
D 2 207 VAL 207 377 377 VAL VAL D . n 
D 2 208 GLN 208 378 378 GLN GLN D . n 
D 2 209 LYS 209 379 379 LYS LYS D . n 
D 2 210 THR 210 380 380 THR THR D . n 
D 2 211 GLY 211 381 381 GLY GLY D . n 
D 2 212 TYR 212 382 382 TYR TYR D . n 
D 2 213 THR 213 383 383 THR THR D . n 
D 2 214 LEU 214 384 384 LEU LEU D . n 
D 2 215 GLU 215 385 385 GLU GLU D . n 
D 2 216 THR 216 386 386 THR THR D . n 
D 2 217 LEU 217 387 387 LEU LEU D . n 
D 2 218 LYS 218 388 388 LYS LYS D . n 
D 2 219 PRO 219 389 389 PRO PRO D . n 
D 2 220 CYS 220 390 390 CYS CYS D . n 
D 2 221 LEU 221 391 391 LEU LEU D . n 
D 2 222 LEU 222 392 392 LEU LEU D . n 
D 2 223 ASP 223 393 393 ASP ASP D . n 
D 2 224 LEU 224 394 394 LEU LEU D . n 
D 2 225 HIS 225 395 395 HIS HIS D . n 
D 2 226 GLN 226 396 396 GLN GLN D . n 
D 2 227 THR 227 397 397 THR THR D . n 
D 2 228 TYR 228 398 398 TYR TYR D . n 
D 2 229 LEU 229 399 399 LEU LEU D . n 
D 2 230 ARG 230 400 400 ARG ARG D . n 
D 2 231 ALA 231 401 401 ALA ALA D . n 
D 2 232 PRO 232 402 402 PRO PRO D . n 
D 2 233 GLN 233 403 403 GLN GLN D . n 
D 2 234 HIS 234 404 404 HIS HIS D . n 
D 2 235 ALA 235 405 405 ALA ALA D . n 
D 2 236 GLN 236 406 406 GLN GLN D . n 
D 2 237 GLN 237 407 407 GLN GLN D . n 
D 2 238 SER 238 408 408 SER SER D . n 
D 2 239 ILE 239 409 409 ILE ILE D . n 
D 2 240 ARG 240 410 410 ARG ARG D . n 
D 2 241 GLU 241 411 411 GLU GLU D . n 
D 2 242 LYS 242 412 412 LYS LYS D . n 
D 2 243 TYR 243 413 413 TYR TYR D . n 
D 2 244 LYS 244 414 414 LYS LYS D . n 
D 2 245 ASN 245 415 415 ASN ASN D . n 
D 2 246 SER 246 416 416 SER SER D . n 
D 2 247 LYS 247 417 417 LYS LYS D . n 
D 2 248 TYR 248 418 418 TYR TYR D . n 
D 2 249 HIS 249 419 419 HIS HIS D . n 
D 2 250 GLY 250 420 420 GLY GLY D . n 
D 2 251 VAL 251 421 421 VAL VAL D . n 
D 2 252 SER 252 422 422 SER SER D . n 
D 2 253 LEU 253 423 423 LEU LEU D . n 
D 2 254 LEU 254 424 424 LEU LEU D . n 
D 2 255 ASN 255 425 425 ASN ASN D . n 
D 2 256 PRO 256 426 426 PRO PRO D . n 
D 2 257 PRO 257 427 427 PRO PRO D . n 
D 2 258 GLU 258 428 428 GLU GLU D . n 
D 2 259 THR 259 429 429 THR THR D . n 
D 2 260 LEU 260 430 430 LEU LEU D . n 
D 2 261 ASN 261 431 431 ASN ASN D . n 
D 2 262 VAL 262 432 432 VAL VAL D . n 
D 2 263 HIS 263 433 ?   ?   ?   D . n 
D 2 264 HIS 264 434 ?   ?   ?   D . n 
D 2 265 HIS 265 435 ?   ?   ?   D . n 
D 2 266 HIS 266 436 ?   ?   ?   D . n 
D 2 267 HIS 267 437 ?   ?   ?   D . n 
D 2 268 HIS 268 438 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        HGQ 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   HGQ 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 HGQ 1  301 606 HGQ DRG A . 
F 3 HGQ 1  302 609 HGQ DRG A . 
G 3 HGQ 1  301 473 HGQ DRG C . 
H 4 HOH 1  401 430 HOH HOH A . 
H 4 HOH 2  402 435 HOH HOH A . 
H 4 HOH 3  403 467 HOH HOH A . 
H 4 HOH 4  404 421 HOH HOH A . 
H 4 HOH 5  405 475 HOH HOH A . 
H 4 HOH 6  406 424 HOH HOH A . 
H 4 HOH 7  407 408 HOH HOH A . 
H 4 HOH 8  408 566 HOH HOH A . 
H 4 HOH 9  409 440 HOH HOH A . 
H 4 HOH 10 410 503 HOH HOH A . 
H 4 HOH 11 411 432 HOH HOH A . 
H 4 HOH 12 412 410 HOH HOH A . 
H 4 HOH 13 413 442 HOH HOH A . 
H 4 HOH 14 414 407 HOH HOH A . 
H 4 HOH 15 415 436 HOH HOH A . 
H 4 HOH 16 416 545 HOH HOH A . 
H 4 HOH 17 417 483 HOH HOH A . 
H 4 HOH 18 418 433 HOH HOH A . 
H 4 HOH 19 419 469 HOH HOH A . 
H 4 HOH 20 420 428 HOH HOH A . 
H 4 HOH 21 421 480 HOH HOH A . 
H 4 HOH 22 422 462 HOH HOH A . 
H 4 HOH 23 423 459 HOH HOH A . 
H 4 HOH 24 424 53  HOH HOH A . 
H 4 HOH 25 425 425 HOH HOH A . 
H 4 HOH 26 426 874 HOH HOH A . 
H 4 HOH 27 427 462 HOH HOH A . 
H 4 HOH 28 428 497 HOH HOH A . 
H 4 HOH 29 429 420 HOH HOH A . 
H 4 HOH 30 430 509 HOH HOH A . 
H 4 HOH 31 431 474 HOH HOH A . 
H 4 HOH 32 432 461 HOH HOH A . 
H 4 HOH 33 433 530 HOH HOH A . 
H 4 HOH 34 434 470 HOH HOH A . 
H 4 HOH 35 435 427 HOH HOH A . 
H 4 HOH 36 436 490 HOH HOH A . 
H 4 HOH 37 437 444 HOH HOH A . 
H 4 HOH 38 438 479 HOH HOH A . 
H 4 HOH 39 439 520 HOH HOH A . 
H 4 HOH 40 440 872 HOH HOH A . 
H 4 HOH 41 441 416 HOH HOH A . 
H 4 HOH 42 442 504 HOH HOH A . 
H 4 HOH 43 443 468 HOH HOH A . 
H 4 HOH 44 444 464 HOH HOH A . 
H 4 HOH 45 445 478 HOH HOH A . 
H 4 HOH 46 446 448 HOH HOH A . 
H 4 HOH 47 447 438 HOH HOH A . 
H 4 HOH 48 448 511 HOH HOH A . 
H 4 HOH 49 449 522 HOH HOH A . 
H 4 HOH 50 450 465 HOH HOH A . 
H 4 HOH 51 451 426 HOH HOH A . 
H 4 HOH 52 452 433 HOH HOH A . 
H 4 HOH 53 453 515 HOH HOH A . 
H 4 HOH 54 454 529 HOH HOH A . 
H 4 HOH 55 455 417 HOH HOH A . 
H 4 HOH 56 456 502 HOH HOH A . 
H 4 HOH 57 457 457 HOH HOH A . 
H 4 HOH 58 458 556 HOH HOH A . 
H 4 HOH 59 459 571 HOH HOH A . 
H 4 HOH 60 460 876 HOH HOH A . 
H 4 HOH 61 461 523 HOH HOH A . 
H 4 HOH 62 462 26  HOH HOH A . 
H 4 HOH 63 463 482 HOH HOH A . 
H 4 HOH 64 464 485 HOH HOH A . 
H 4 HOH 65 465 532 HOH HOH A . 
H 4 HOH 66 466 447 HOH HOH A . 
H 4 HOH 67 467 524 HOH HOH A . 
H 4 HOH 68 468 500 HOH HOH A . 
H 4 HOH 69 469 527 HOH HOH A . 
H 4 HOH 70 470 544 HOH HOH A . 
H 4 HOH 71 471 875 HOH HOH A . 
H 4 HOH 72 472 486 HOH HOH A . 
H 4 HOH 73 473 484 HOH HOH A . 
H 4 HOH 74 474 526 HOH HOH A . 
H 4 HOH 75 475 455 HOH HOH A . 
H 4 HOH 76 476 495 HOH HOH A . 
H 4 HOH 77 477 456 HOH HOH A . 
H 4 HOH 78 478 466 HOH HOH A . 
H 4 HOH 79 479 507 HOH HOH A . 
H 4 HOH 80 480 472 HOH HOH A . 
H 4 HOH 81 481 577 HOH HOH A . 
H 4 HOH 82 482 552 HOH HOH A . 
H 4 HOH 83 483 886 HOH HOH A . 
H 4 HOH 84 484 542 HOH HOH A . 
H 4 HOH 85 485 573 HOH HOH A . 
H 4 HOH 86 486 570 HOH HOH A . 
H 4 HOH 87 487 559 HOH HOH A . 
H 4 HOH 88 488 579 HOH HOH A . 
H 4 HOH 89 489 588 HOH HOH A . 
I 4 HOH 1  501 415 HOH HOH B . 
I 4 HOH 2  502 553 HOH HOH B . 
I 4 HOH 3  503 534 HOH HOH B . 
I 4 HOH 4  504 506 HOH HOH B . 
I 4 HOH 5  505 622 HOH HOH B . 
I 4 HOH 6  506 509 HOH HOH B . 
I 4 HOH 7  507 532 HOH HOH B . 
I 4 HOH 8  508 438 HOH HOH B . 
I 4 HOH 9  509 522 HOH HOH B . 
I 4 HOH 10 510 521 HOH HOH B . 
I 4 HOH 11 511 644 HOH HOH B . 
I 4 HOH 12 512 508 HOH HOH B . 
I 4 HOH 13 513 447 HOH HOH B . 
I 4 HOH 14 514 555 HOH HOH B . 
I 4 HOH 15 515 524 HOH HOH B . 
I 4 HOH 16 516 538 HOH HOH B . 
I 4 HOH 17 517 537 HOH HOH B . 
I 4 HOH 18 518 451 HOH HOH B . 
I 4 HOH 19 519 607 HOH HOH B . 
I 4 HOH 20 520 604 HOH HOH B . 
I 4 HOH 21 521 531 HOH HOH B . 
I 4 HOH 22 522 571 HOH HOH B . 
I 4 HOH 23 523 568 HOH HOH B . 
I 4 HOH 24 524 597 HOH HOH B . 
I 4 HOH 25 525 543 HOH HOH B . 
I 4 HOH 26 526 585 HOH HOH B . 
I 4 HOH 27 527 166 HOH HOH B . 
I 4 HOH 28 528 570 HOH HOH B . 
I 4 HOH 29 529 563 HOH HOH B . 
I 4 HOH 30 530 512 HOH HOH B . 
I 4 HOH 31 531 595 HOH HOH B . 
I 4 HOH 32 532 589 HOH HOH B . 
I 4 HOH 33 533 615 HOH HOH B . 
I 4 HOH 34 534 633 HOH HOH B . 
I 4 HOH 35 535 558 HOH HOH B . 
I 4 HOH 36 536 572 HOH HOH B . 
I 4 HOH 37 537 880 HOH HOH B . 
I 4 HOH 38 538 560 HOH HOH B . 
I 4 HOH 39 539 511 HOH HOH B . 
I 4 HOH 40 540 552 HOH HOH B . 
I 4 HOH 41 541 477 HOH HOH B . 
I 4 HOH 42 542 556 HOH HOH B . 
I 4 HOH 43 543 530 HOH HOH B . 
I 4 HOH 44 544 520 HOH HOH B . 
I 4 HOH 45 545 600 HOH HOH B . 
I 4 HOH 46 546 564 HOH HOH B . 
I 4 HOH 47 547 554 HOH HOH B . 
I 4 HOH 48 548 523 HOH HOH B . 
I 4 HOH 49 549 883 HOH HOH B . 
I 4 HOH 50 550 593 HOH HOH B . 
I 4 HOH 51 551 581 HOH HOH B . 
I 4 HOH 52 552 566 HOH HOH B . 
I 4 HOH 53 553 616 HOH HOH B . 
I 4 HOH 54 554 642 HOH HOH B . 
I 4 HOH 55 555 598 HOH HOH B . 
I 4 HOH 56 556 612 HOH HOH B . 
I 4 HOH 57 557 458 HOH HOH B . 
I 4 HOH 58 558 617 HOH HOH B . 
I 4 HOH 59 559 599 HOH HOH B . 
I 4 HOH 60 560 546 HOH HOH B . 
I 4 HOH 61 561 656 HOH HOH B . 
I 4 HOH 62 562 627 HOH HOH B . 
I 4 HOH 63 563 628 HOH HOH B . 
I 4 HOH 64 564 631 HOH HOH B . 
I 4 HOH 65 565 605 HOH HOH B . 
I 4 HOH 66 566 579 HOH HOH B . 
I 4 HOH 67 567 594 HOH HOH B . 
I 4 HOH 68 568 582 HOH HOH B . 
I 4 HOH 69 569 463 HOH HOH B . 
I 4 HOH 70 570 630 HOH HOH B . 
I 4 HOH 71 571 434 HOH HOH B . 
I 4 HOH 72 572 636 HOH HOH B . 
I 4 HOH 73 573 609 HOH HOH B . 
I 4 HOH 74 574 574 HOH HOH B . 
I 4 HOH 75 575 640 HOH HOH B . 
I 4 HOH 76 576 637 HOH HOH B . 
I 4 HOH 77 577 619 HOH HOH B . 
I 4 HOH 78 578 620 HOH HOH B . 
I 4 HOH 79 579 634 HOH HOH B . 
I 4 HOH 80 580 466 HOH HOH B . 
I 4 HOH 81 581 629 HOH HOH B . 
I 4 HOH 82 582 479 HOH HOH B . 
I 4 HOH 83 583 559 HOH HOH B . 
I 4 HOH 84 584 657 HOH HOH B . 
I 4 HOH 85 585 641 HOH HOH B . 
I 4 HOH 86 586 650 HOH HOH B . 
I 4 HOH 87 587 866 HOH HOH B . 
I 4 HOH 88 588 667 HOH HOH B . 
I 4 HOH 89 589 663 HOH HOH B . 
I 4 HOH 90 590 473 HOH HOH B . 
I 4 HOH 91 591 321 HOH HOH B . 
I 4 HOH 92 592 674 HOH HOH B . 
I 4 HOH 93 593 676 HOH HOH B . 
I 4 HOH 94 594 675 HOH HOH B . 
I 4 HOH 95 595 672 HOH HOH B . 
I 4 HOH 96 596 257 HOH HOH B . 
I 4 HOH 97 597 680 HOH HOH B . 
J 4 HOH 1  401 406 HOH HOH C . 
J 4 HOH 2  402 407 HOH HOH C . 
J 4 HOH 3  403 414 HOH HOH C . 
J 4 HOH 4  404 226 HOH HOH C . 
J 4 HOH 5  405 410 HOH HOH C . 
J 4 HOH 6  406 3   HOH HOH C . 
J 4 HOH 7  407 94  HOH HOH C . 
J 4 HOH 8  408 425 HOH HOH C . 
J 4 HOH 9  409 436 HOH HOH C . 
J 4 HOH 10 410 430 HOH HOH C . 
J 4 HOH 11 411 437 HOH HOH C . 
J 4 HOH 12 412 404 HOH HOH C . 
J 4 HOH 13 413 440 HOH HOH C . 
J 4 HOH 14 414 448 HOH HOH C . 
J 4 HOH 15 415 432 HOH HOH C . 
J 4 HOH 16 416 460 HOH HOH C . 
J 4 HOH 17 417 434 HOH HOH C . 
J 4 HOH 18 418 428 HOH HOH C . 
J 4 HOH 19 419 426 HOH HOH C . 
J 4 HOH 20 420 439 HOH HOH C . 
J 4 HOH 21 421 424 HOH HOH C . 
J 4 HOH 22 422 452 HOH HOH C . 
J 4 HOH 23 423 498 HOH HOH C . 
J 4 HOH 24 424 438 HOH HOH C . 
J 4 HOH 25 425 412 HOH HOH C . 
J 4 HOH 26 426 525 HOH HOH C . 
J 4 HOH 27 427 427 HOH HOH C . 
J 4 HOH 28 428 449 HOH HOH C . 
J 4 HOH 29 429 433 HOH HOH C . 
J 4 HOH 30 430 446 HOH HOH C . 
J 4 HOH 31 431 419 HOH HOH C . 
J 4 HOH 32 432 453 HOH HOH C . 
J 4 HOH 33 433 447 HOH HOH C . 
J 4 HOH 34 434 450 HOH HOH C . 
J 4 HOH 35 435 153 HOH HOH C . 
J 4 HOH 36 436 104 HOH HOH C . 
J 4 HOH 37 437 461 HOH HOH C . 
J 4 HOH 38 438 408 HOH HOH C . 
J 4 HOH 39 439 465 HOH HOH C . 
J 4 HOH 40 440 22  HOH HOH C . 
J 4 HOH 41 441 446 HOH HOH C . 
J 4 HOH 42 442 62  HOH HOH C . 
J 4 HOH 43 443 20  HOH HOH C . 
J 4 HOH 44 444 451 HOH HOH C . 
J 4 HOH 45 445 81  HOH HOH C . 
J 4 HOH 46 446 414 HOH HOH C . 
J 4 HOH 47 447 464 HOH HOH C . 
J 4 HOH 48 448 888 HOH HOH C . 
J 4 HOH 49 449 429 HOH HOH C . 
J 4 HOH 50 450 468 HOH HOH C . 
J 4 HOH 51 451 870 HOH HOH C . 
J 4 HOH 52 452 51  HOH HOH C . 
J 4 HOH 53 453 8   HOH HOH C . 
K 4 HOH 1  501 501 HOH HOH D . 
K 4 HOH 2  502 4   HOH HOH D . 
K 4 HOH 3  503 7   HOH HOH D . 
K 4 HOH 4  504 882 HOH HOH D . 
K 4 HOH 5  505 547 HOH HOH D . 
K 4 HOH 6  506 522 HOH HOH D . 
K 4 HOH 7  507 502 HOH HOH D . 
K 4 HOH 8  508 537 HOH HOH D . 
K 4 HOH 9  509 527 HOH HOH D . 
K 4 HOH 10 510 529 HOH HOH D . 
K 4 HOH 11 511 532 HOH HOH D . 
K 4 HOH 12 512 512 HOH HOH D . 
K 4 HOH 13 513 526 HOH HOH D . 
K 4 HOH 14 514 511 HOH HOH D . 
K 4 HOH 15 515 555 HOH HOH D . 
K 4 HOH 16 516 552 HOH HOH D . 
K 4 HOH 17 517 13  HOH HOH D . 
K 4 HOH 18 518 524 HOH HOH D . 
K 4 HOH 19 519 520 HOH HOH D . 
K 4 HOH 20 520 521 HOH HOH D . 
K 4 HOH 21 521 505 HOH HOH D . 
K 4 HOH 22 522 455 HOH HOH D . 
K 4 HOH 23 523 491 HOH HOH D . 
K 4 HOH 24 524 544 HOH HOH D . 
K 4 HOH 25 525 507 HOH HOH D . 
K 4 HOH 26 526 884 HOH HOH D . 
K 4 HOH 27 527 881 HOH HOH D . 
K 4 HOH 28 528 517 HOH HOH D . 
K 4 HOH 29 529 523 HOH HOH D . 
K 4 HOH 30 530 533 HOH HOH D . 
K 4 HOH 31 531 482 HOH HOH D . 
K 4 HOH 32 532 484 HOH HOH D . 
K 4 HOH 33 533 550 HOH HOH D . 
K 4 HOH 34 534 562 HOH HOH D . 
K 4 HOH 35 535 57  HOH HOH D . 
K 4 HOH 36 536 24  HOH HOH D . 
K 4 HOH 37 537 457 HOH HOH D . 
K 4 HOH 38 538 469 HOH HOH D . 
K 4 HOH 39 539 879 HOH HOH D . 
K 4 HOH 40 540 553 HOH HOH D . 
K 4 HOH 41 541 570 HOH HOH D . 
K 4 HOH 42 542 560 HOH HOH D . 
K 4 HOH 43 543 557 HOH HOH D . 
K 4 HOH 44 544 568 HOH HOH D . 
K 4 HOH 45 545 569 HOH HOH D . 
K 4 HOH 46 546 572 HOH HOH D . 
K 4 HOH 47 547 873 HOH HOH D . 
K 4 HOH 48 548 579 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ET7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.181 
_cell.length_a_esd                 ? 
_cell.length_b                     133.725 
_cell.length_b_esd                 ? 
_cell.length_c                     147.94 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ET7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ET7 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.81 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.30 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.8984362017286718 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.8984362017286718 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ET7 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.3 
_reflns.d_resolution_low                               147.94 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     62435 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           94.3 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.136 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.3 
_reflns_shell.d_res_low                                     2.36 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.8 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4816 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.4 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.71 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.4 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -1.975 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            1.573 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.402 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               36.291 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.946 
_refine.correlation_coeff_Fo_to_Fc_free          0.938 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ET7 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.312 
_refine.ls_d_res_low                             99.401 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     60549 
_refine.ls_number_reflns_R_free                  3100 
_refine.ls_number_reflns_R_work                  57449 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    93.016 
_refine.ls_percent_reflns_R_free                 5.120 
_refine.ls_R_factor_all                          0.241 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2713 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2394 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.251 
_refine.ls_wR_factor_R_work                      0.225 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.393 
_refine.pdbx_overall_ESU_R_Free                  0.264 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9384 
_refine.pdbx_average_fsc_free                    0.9250 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.312 
_refine_hist.d_res_low                        99.401 
_refine_hist.number_atoms_solvent             287 
_refine_hist.number_atoms_total               9271 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8960 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         24 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.012  9274  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.468  1.846  12609 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 5.748  5.000  1122  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 24.432 5.000  45    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 12.506 10.000 1617  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.610 10.000 404   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.068  0.200  1423  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.005  0.020  6984  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.210  0.200  4169  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.310  0.200  6425  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.152  0.200  380   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.234  0.200  57    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.220  0.200  15    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.488  3.398  4482  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.905  6.110  5606  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.034  3.716  4792  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.870  6.697  7003  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.842  38.237 13992 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.312  2.373  4716 . 206 3757 84.0331  . 1.424 . . 1.422 . . . . . 1.561 . 20 . 0.749 0.760 1.465 
'X-RAY DIFFRACTION' 2.373  2.438  4640 . 251 4389 100.0000 . 0.534 . . 0.531 . . . . . 0.553 . 20 . 0.861 0.857 0.578 
'X-RAY DIFFRACTION' 2.438  2.508  4504 . 241 4263 100.0000 . 0.374 . . 0.370 . . . . . 0.372 . 20 . 0.931 0.911 0.434 
'X-RAY DIFFRACTION' 2.508  2.585  4387 . 235 4152 100.0000 . 0.293 . . 0.291 . . . . . 0.286 . 20 . 0.944 0.914 0.344 
'X-RAY DIFFRACTION' 2.585  2.670  4266 . 193 3274 81.2705  . 0.281 . . 0.280 . . . . . 0.273 . 20 . 0.950 0.939 0.288 
'X-RAY DIFFRACTION' 2.670  2.764  4111 . 173 3193 81.8779  . 0.283 . . 0.280 . . . . . 0.268 . 20 . 0.949 0.934 0.332 
'X-RAY DIFFRACTION' 2.764  2.868  3953 . 184 3769 100.0000 . 0.279 . . 0.277 . . . . . 0.263 . 20 . 0.951 0.929 0.329 
'X-RAY DIFFRACTION' 2.868  2.985  3844 . 186 3658 100.0000 . 0.276 . . 0.275 . . . . . 0.261 . 20 . 0.952 0.938 0.302 
'X-RAY DIFFRACTION' 2.985  3.117  3691 . 181 3510 100.0000 . 0.273 . . 0.270 . . . . . 0.257 . 20 . 0.955 0.931 0.342 
'X-RAY DIFFRACTION' 3.117  3.269  3513 . 184 3329 100.0000 . 0.261 . . 0.261 . . . . . 0.248 . 20 . 0.960 0.956 0.270 
'X-RAY DIFFRACTION' 3.269  3.446  3352 . 167 2760 87.3210  . 0.246 . . 0.244 . . . . . 0.235 . 20 . 0.965 0.945 0.287 
'X-RAY DIFFRACTION' 3.446  3.655  3183 . 107 2359 77.4741  . 0.230 . . 0.226 . . . . . 0.219 . 20 . 0.971 0.938 0.319 
'X-RAY DIFFRACTION' 3.655  3.907  3017 . 99  1968 68.5118  . 0.205 . . 0.204 . . . . . 0.198 . 20 . 0.976 0.968 0.224 
'X-RAY DIFFRACTION' 3.907  4.219  2779 . 131 2513 95.1421  . 0.196 . . 0.195 . . . . . 0.191 . 20 . 0.979 0.970 0.215 
'X-RAY DIFFRACTION' 4.219  4.621  2619 . 139 2480 100.0000 . 0.180 . . 0.180 . . . . . 0.178 . 20 . 0.982 0.981 0.177 
'X-RAY DIFFRACTION' 4.621  5.165  2335 . 123 2212 100.0000 . 0.182 . . 0.180 . . . . . 0.178 . 20 . 0.980 0.970 0.226 
'X-RAY DIFFRACTION' 5.165  5.962  2096 . 111 1985 100.0000 . 0.212 . . 0.211 . . . . . 0.206 . 20 . 0.976 0.975 0.224 
'X-RAY DIFFRACTION' 5.962  7.295  1803 . 85  1718 100.0000 . 0.215 . . 0.213 . . . . . 0.208 . 20 . 0.977 0.962 0.262 
'X-RAY DIFFRACTION' 7.295  10.289 1422 . 71  1351 100.0000 . 0.153 . . 0.151 . . . . . 0.157 . 20 . 0.987 0.983 0.179 
'X-RAY DIFFRACTION' 10.289 99.401 844  . 33  809  99.7630  . 0.206 . . 0.207 . . . . . 0.240 . 20 . 0.968 0.982 0.192 
# 
_struct.entry_id                     9ET7 
_struct.title                        'CDK2-cyclin A in complex with FragLite 6' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ET7 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CDK2_HUMAN  P24941 ? 1 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
2 UNP CCNA2_BOVIN P30274 ? 2 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ET7 A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
2 2 9ET7 B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
3 1 9ET7 C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
4 2 9ET7 D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ET7 GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  1  
1 9ET7 PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  2  
1 9ET7 GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  3  
1 9ET7 SER A 4   ? UNP P24941 ? ? 'expression tag' 0   4  
2 9ET7 GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 5  
2 9ET7 HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 6  
2 9ET7 HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 7  
2 9ET7 HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 8  
2 9ET7 HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 9  
2 9ET7 HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 10 
2 9ET7 HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 11 
3 9ET7 GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  12 
3 9ET7 PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  13 
3 9ET7 GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  14 
3 9ET7 SER C 4   ? UNP P24941 ? ? 'expression tag' 0   15 
4 9ET7 GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 16 
4 9ET7 HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 17 
4 9ET7 HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 18 
4 9ET7 HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 19 
4 9ET7 HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 20 
4 9ET7 HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 21 
4 9ET7 HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3530  ? 
1 MORE         -16   ? 
1 'SSA (A^2)'  23130 ? 
2 'ABSA (A^2)' 3680  ? 
2 MORE         -18   ? 
2 'SSA (A^2)'  23180 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,H,I 
2 1 C,D,G,J,K   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 4   ? GLU A 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P2  AA2 PRO A 49  ? LEU A 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 91  ? SER A 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P4  AA4 PRO A 104 ? HIS A 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P5  AA5 LYS A 133 ? GLN A 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P6  AA6 ASP A 149 ? ALA A 153 ? ASP A 145 ALA A 149 5 ? 5  
HELX_P HELX_P7  AA7 THR A 169 ? ARG A 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P8  AA8 ALA A 174 ? LEU A 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P9  AA9 THR A 186 ? ARG A 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P10 AB1 SER A 211 ? GLY A 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P11 AB2 GLY A 233 ? MET A 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P12 AB3 ASP A 251 ? VAL A 255 ? ASP A 247 VAL A 251 5 ? 5  
HELX_P HELX_P13 AB4 ASP A 260 ? LEU A 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P14 AB5 SER A 280 ? LEU A 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P15 AB6 ALA A 286 ? GLN A 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P16 AB7 GLY B 1   ? VAL B 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P17 AB8 TYR B 8   ? CYS B 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P18 AB9 GLY B 28  ? GLN B 33  ? GLY B 198 GLN B 203 5 ? 6  
HELX_P HELX_P19 AC1 THR B 37  ? TYR B 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P20 AC2 GLN B 58  ? MET B 76  ? GLN B 228 MET B 246 1 ? 19 
HELX_P HELX_P21 AC3 LEU B 79  ? GLU B 99  ? LEU B 249 GLU B 269 1 ? 21 
HELX_P HELX_P22 AC4 GLU B 104 ? ILE B 111 ? GLU B 274 ILE B 281 1 ? 8  
HELX_P HELX_P23 AC5 THR B 117 ? LEU B 132 ? THR B 287 LEU B 302 1 ? 16 
HELX_P HELX_P24 AC6 THR B 140 ? LEU B 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P25 AC7 ASN B 156 ? ASP B 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P26 AC8 ASP B 173 ? LEU B 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P27 AC9 LEU B 181 ? GLY B 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P28 AD1 PRO B 203 ? GLY B 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P29 AD2 THR B 213 ? ALA B 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P30 AD3 PRO B 232 ? HIS B 234 ? PRO B 402 HIS B 404 5 ? 3  
HELX_P HELX_P31 AD4 GLN B 237 ? TYR B 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P32 AD5 LYS B 244 ? HIS B 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P33 AD6 GLY B 250 ? LEU B 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P34 AD7 PRO C 49  ? LEU C 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P35 AD8 LEU C 91  ? SER C 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P36 AD9 PRO C 104 ? HIS C 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P37 AE1 LYS C 133 ? GLN C 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P38 AE2 ASP C 149 ? ALA C 153 ? ASP C 145 ALA C 149 5 ? 5  
HELX_P HELX_P39 AE3 THR C 169 ? ARG C 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P40 AE4 ALA C 174 ? LEU C 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P41 AE5 THR C 186 ? ARG C 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P42 AE6 SER C 211 ? GLY C 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P43 AE7 GLY C 233 ? MET C 237 ? GLY C 229 MET C 233 5 ? 5  
HELX_P HELX_P44 AE8 ASP C 251 ? VAL C 256 ? ASP C 247 VAL C 252 1 ? 6  
HELX_P HELX_P45 AE9 ASP C 260 ? LEU C 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P46 AF1 SER C 280 ? LEU C 285 ? SER C 276 LEU C 281 1 ? 6  
HELX_P HELX_P47 AF2 ALA C 286 ? GLN C 291 ? ALA C 282 GLN C 287 5 ? 6  
HELX_P HELX_P48 AF3 GLY D 1   ? VAL D 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P49 AF4 TYR D 8   ? CYS D 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P50 AF5 GLY D 28  ? GLN D 33  ? GLY D 198 GLN D 203 5 ? 6  
HELX_P HELX_P51 AF6 THR D 37  ? TYR D 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P52 AF7 GLN D 58  ? MET D 76  ? GLN D 228 MET D 246 1 ? 19 
HELX_P HELX_P53 AF8 LEU D 79  ? GLY D 81  ? LEU D 249 GLY D 251 5 ? 3  
HELX_P HELX_P54 AF9 LYS D 82  ? GLU D 99  ? LYS D 252 GLU D 269 1 ? 18 
HELX_P HELX_P55 AG1 GLU D 104 ? ILE D 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P56 AG2 THR D 117 ? LEU D 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P57 AG3 THR D 140 ? LEU D 150 ? THR D 310 LEU D 320 1 ? 11 
HELX_P HELX_P58 AG4 ASN D 156 ? ASP D 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P59 AG5 ASP D 173 ? LEU D 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P60 AG6 LEU D 181 ? GLY D 199 ? LEU D 351 GLY D 369 1 ? 19 
HELX_P HELX_P61 AG7 PRO D 203 ? GLY D 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P62 AG8 THR D 213 ? ALA D 231 ? THR D 383 ALA D 401 1 ? 19 
HELX_P HELX_P63 AG9 PRO D 232 ? HIS D 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P64 AH1 GLN D 237 ? TYR D 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P65 AH2 LYS D 244 ? HIS D 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P66 AH3 GLY D 250 ? LEU D 254 ? GLY D 420 LEU D 424 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A TYR 163 C ? ? ? 1_555 A TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.336 ? ? 
covale2 covale both ? A TPO 164 C ? ? ? 1_555 A HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.337 ? ? 
covale3 covale both ? C TYR 163 C ? ? ? 1_555 C TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.338 ? ? 
covale4 covale both ? C TPO 164 C ? ? ? 1_555 C HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.340 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO A 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO C 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 158 A . ? VAL 154 A PRO 159 A ? PRO 155 A 1 -4.84 
2 GLN 153 B . ? GLN 323 B PRO 154 B ? PRO 324 B 1 -4.84 
3 ASP 175 B . ? ASP 345 B PRO 176 B ? PRO 346 B 1 8.51  
4 VAL 158 C . ? VAL 154 C PRO 159 C ? PRO 155 C 1 -4.08 
5 GLN 153 D . ? GLN 323 D PRO 154 D ? PRO 324 D 1 -4.44 
6 ASP 175 D . ? ASP 345 D PRO 176 D ? PRO 346 D 1 8.58  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 8   ? GLY A 17  ? PHE A 4   GLY A 13  
AA1 2 GLY A 20  ? ASN A 27  ? GLY A 16  ASN A 23  
AA1 3 VAL A 33  ? ARG A 40  ? VAL A 29  ARG A 36  
AA1 4 LYS A 79  ? GLU A 85  ? LYS A 75  GLU A 81  
AA1 5 LEU A 70  ? HIS A 75  ? LEU A 66  HIS A 71  
AA2 1 GLN A 89  ? ASP A 90  ? GLN A 85  ASP A 86  
AA2 2 LEU A 137 ? ILE A 139 ? LEU A 133 ILE A 135 
AA2 3 ILE A 145 ? LEU A 147 ? ILE A 141 LEU A 143 
AA3 1 VAL A 127 ? LEU A 128 ? VAL A 123 LEU A 124 
AA3 2 ARG A 154 ? ALA A 155 ? ARG A 150 ALA A 151 
AA4 1 PHE C 8   ? GLU C 16  ? PHE C 4   GLU C 12  
AA4 2 VAL C 21  ? ASN C 27  ? VAL C 17  ASN C 23  
AA4 3 VAL C 33  ? ARG C 40  ? VAL C 29  ARG C 36  
AA4 4 LYS C 79  ? GLU C 85  ? LYS C 75  GLU C 81  
AA4 5 LEU C 70  ? HIS C 75  ? LEU C 66  HIS C 71  
AA5 1 GLN C 89  ? ASP C 90  ? GLN C 85  ASP C 86  
AA5 2 LEU C 137 ? ILE C 139 ? LEU C 133 ILE C 135 
AA5 3 ILE C 145 ? LEU C 147 ? ILE C 141 LEU C 143 
AA6 1 VAL C 127 ? LEU C 128 ? VAL C 123 LEU C 124 
AA6 2 ARG C 154 ? ALA C 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 11  ? N VAL A 7   O LYS A 24  ? O LYS A 20  
AA1 2 3 N ALA A 25  ? N ALA A 21  O VAL A 34  ? O VAL A 30  
AA1 3 4 N ILE A 39  ? N ILE A 35  O LEU A 80  ? O LEU A 76  
AA1 4 5 O VAL A 83  ? O VAL A 79  N LEU A 71  ? N LEU A 67  
AA2 1 2 N GLN A 89  ? N GLN A 85  O ILE A 139 ? O ILE A 135 
AA2 2 3 N LEU A 138 ? N LEU A 134 O LYS A 146 ? O LYS A 142 
AA3 1 2 N LEU A 128 ? N LEU A 124 O ARG A 154 ? O ARG A 150 
AA4 1 2 N VAL C 11  ? N VAL C 7   O LYS C 24  ? O LYS C 20  
AA4 2 3 N ALA C 25  ? N ALA C 21  O VAL C 34  ? O VAL C 30  
AA4 3 4 N ILE C 39  ? N ILE C 35  O LEU C 80  ? O LEU C 76  
AA4 4 5 O VAL C 83  ? O VAL C 79  N LEU C 71  ? N LEU C 67  
AA5 1 2 N GLN C 89  ? N GLN C 85  O ILE C 139 ? O ILE C 135 
AA5 2 3 N LEU C 138 ? N LEU C 134 O LYS C 146 ? O LYS C 142 
AA6 1 2 N LEU C 128 ? N LEU C 124 O ARG C 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ET7 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR A 15  ? ? 73.45   -18.93  
2  1 ASP A 127 ? ? -156.16 47.66   
3  1 ASP A 145 ? ? 60.98   76.23   
4  1 GLU A 162 ? ? 60.98   76.93   
5  1 VAL A 164 ? ? 75.76   128.99  
6  1 SER A 181 ? ? -144.92 -157.89 
7  1 VAL B 175 ? ? 31.22   70.35   
8  1 TRP B 372 ? ? -33.61  113.78  
9  1 THR C 41  ? ? -127.04 -77.49  
10 1 ASP C 127 ? ? -153.65 47.70   
11 1 ASP C 145 ? ? 57.60   75.53   
12 1 VAL C 164 ? ? 73.21   128.16  
13 1 SER C 181 ? ? -144.56 -157.80 
14 1 THR C 290 ? ? -121.07 -169.85 
15 1 VAL D 175 ? ? 32.66   69.25   
16 1 TRP D 372 ? ? -31.28  113.66  
17 1 ASN D 431 ? ? 67.64   102.51  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 122 ? ? 0.299 'SIDE CHAIN' 
2  1 ARG A 199 ? ? 0.078 'SIDE CHAIN' 
3  1 ARG A 217 ? ? 0.087 'SIDE CHAIN' 
4  1 ARG B 187 ? ? 0.079 'SIDE CHAIN' 
5  1 ARG B 293 ? ? 0.216 'SIDE CHAIN' 
6  1 ARG C 150 ? ? 0.157 'SIDE CHAIN' 
7  1 ARG C 199 ? ? 0.096 'SIDE CHAIN' 
8  1 ARG C 217 ? A 0.283 'SIDE CHAIN' 
9  1 ARG C 245 ? ? 0.113 'SIDE CHAIN' 
10 1 ARG D 187 ? ? 0.083 'SIDE CHAIN' 
11 1 ARG D 400 ? ? 0.091 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 A TPO 164 A TPO 160 ? THR 'modified residue' 
2 C TPO 164 C TPO 160 ? THR 'modified residue' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A THR 290 ? A THR 294 
2  1 Y 1 A LYS 291 ? A LYS 295 
3  1 Y 1 A PRO 292 ? A PRO 296 
4  1 Y 1 A VAL 293 ? A VAL 297 
5  1 Y 1 A PRO 294 ? A PRO 298 
6  1 Y 1 A HIS 295 ? A HIS 299 
7  1 Y 1 A LEU 296 ? A LEU 300 
8  1 Y 1 A ARG 297 ? A ARG 301 
9  1 Y 1 A LEU 298 ? A LEU 302 
10 1 Y 1 B HIS 433 ? B HIS 263 
11 1 Y 1 B HIS 434 ? B HIS 264 
12 1 Y 1 B HIS 435 ? B HIS 265 
13 1 Y 1 B HIS 436 ? B HIS 266 
14 1 Y 1 B HIS 437 ? B HIS 267 
15 1 Y 1 B HIS 438 ? B HIS 268 
16 1 Y 1 C GLY -3  ? C GLY 1   
17 1 Y 1 C PRO -2  ? C PRO 2   
18 1 Y 1 C GLY -1  ? C GLY 3   
19 1 Y 1 C ARG 297 ? C ARG 301 
20 1 Y 1 C LEU 298 ? C LEU 302 
21 1 Y 1 D HIS 433 ? D HIS 263 
22 1 Y 1 D HIS 434 ? D HIS 264 
23 1 Y 1 D HIS 435 ? D HIS 265 
24 1 Y 1 D HIS 436 ? D HIS 266 
25 1 Y 1 D HIS 437 ? D HIS 267 
26 1 Y 1 D HIS 438 ? D HIS 268 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HGQ C4   C  N N 137 
HGQ C5   C  N N 138 
HGQ N1   N  N N 139 
HGQ C3   C  N N 140 
HGQ O1   O  N N 141 
HGQ C1   C  N N 142 
HGQ C2   C  N N 143 
HGQ BR1  BR N N 144 
HGQ H1   H  N N 145 
HGQ H2   H  N N 146 
HGQ H3   H  N N 147 
HGQ H4   H  N N 148 
HIS N    N  N N 149 
HIS CA   C  N S 150 
HIS C    C  N N 151 
HIS O    O  N N 152 
HIS CB   C  N N 153 
HIS CG   C  Y N 154 
HIS ND1  N  Y N 155 
HIS CD2  C  Y N 156 
HIS CE1  C  Y N 157 
HIS NE2  N  Y N 158 
HIS OXT  O  N N 159 
HIS H    H  N N 160 
HIS H2   H  N N 161 
HIS HA   H  N N 162 
HIS HB2  H  N N 163 
HIS HB3  H  N N 164 
HIS HD1  H  N N 165 
HIS HD2  H  N N 166 
HIS HE1  H  N N 167 
HIS HE2  H  N N 168 
HIS HXT  H  N N 169 
HOH O    O  N N 170 
HOH H1   H  N N 171 
HOH H2   H  N N 172 
ILE N    N  N N 173 
ILE CA   C  N S 174 
ILE C    C  N N 175 
ILE O    O  N N 176 
ILE CB   C  N S 177 
ILE CG1  C  N N 178 
ILE CG2  C  N N 179 
ILE CD1  C  N N 180 
ILE OXT  O  N N 181 
ILE H    H  N N 182 
ILE H2   H  N N 183 
ILE HA   H  N N 184 
ILE HB   H  N N 185 
ILE HG12 H  N N 186 
ILE HG13 H  N N 187 
ILE HG21 H  N N 188 
ILE HG22 H  N N 189 
ILE HG23 H  N N 190 
ILE HD11 H  N N 191 
ILE HD12 H  N N 192 
ILE HD13 H  N N 193 
ILE HXT  H  N N 194 
LEU N    N  N N 195 
LEU CA   C  N S 196 
LEU C    C  N N 197 
LEU O    O  N N 198 
LEU CB   C  N N 199 
LEU CG   C  N N 200 
LEU CD1  C  N N 201 
LEU CD2  C  N N 202 
LEU OXT  O  N N 203 
LEU H    H  N N 204 
LEU H2   H  N N 205 
LEU HA   H  N N 206 
LEU HB2  H  N N 207 
LEU HB3  H  N N 208 
LEU HG   H  N N 209 
LEU HD11 H  N N 210 
LEU HD12 H  N N 211 
LEU HD13 H  N N 212 
LEU HD21 H  N N 213 
LEU HD22 H  N N 214 
LEU HD23 H  N N 215 
LEU HXT  H  N N 216 
LYS N    N  N N 217 
LYS CA   C  N S 218 
LYS C    C  N N 219 
LYS O    O  N N 220 
LYS CB   C  N N 221 
LYS CG   C  N N 222 
LYS CD   C  N N 223 
LYS CE   C  N N 224 
LYS NZ   N  N N 225 
LYS OXT  O  N N 226 
LYS H    H  N N 227 
LYS H2   H  N N 228 
LYS HA   H  N N 229 
LYS HB2  H  N N 230 
LYS HB3  H  N N 231 
LYS HG2  H  N N 232 
LYS HG3  H  N N 233 
LYS HD2  H  N N 234 
LYS HD3  H  N N 235 
LYS HE2  H  N N 236 
LYS HE3  H  N N 237 
LYS HZ1  H  N N 238 
LYS HZ2  H  N N 239 
LYS HZ3  H  N N 240 
LYS HXT  H  N N 241 
MET N    N  N N 242 
MET CA   C  N S 243 
MET C    C  N N 244 
MET O    O  N N 245 
MET CB   C  N N 246 
MET CG   C  N N 247 
MET SD   S  N N 248 
MET CE   C  N N 249 
MET OXT  O  N N 250 
MET H    H  N N 251 
MET H2   H  N N 252 
MET HA   H  N N 253 
MET HB2  H  N N 254 
MET HB3  H  N N 255 
MET HG2  H  N N 256 
MET HG3  H  N N 257 
MET HE1  H  N N 258 
MET HE2  H  N N 259 
MET HE3  H  N N 260 
MET HXT  H  N N 261 
PHE N    N  N N 262 
PHE CA   C  N S 263 
PHE C    C  N N 264 
PHE O    O  N N 265 
PHE CB   C  N N 266 
PHE CG   C  Y N 267 
PHE CD1  C  Y N 268 
PHE CD2  C  Y N 269 
PHE CE1  C  Y N 270 
PHE CE2  C  Y N 271 
PHE CZ   C  Y N 272 
PHE OXT  O  N N 273 
PHE H    H  N N 274 
PHE H2   H  N N 275 
PHE HA   H  N N 276 
PHE HB2  H  N N 277 
PHE HB3  H  N N 278 
PHE HD1  H  N N 279 
PHE HD2  H  N N 280 
PHE HE1  H  N N 281 
PHE HE2  H  N N 282 
PHE HZ   H  N N 283 
PHE HXT  H  N N 284 
PRO N    N  N N 285 
PRO CA   C  N S 286 
PRO C    C  N N 287 
PRO O    O  N N 288 
PRO CB   C  N N 289 
PRO CG   C  N N 290 
PRO CD   C  N N 291 
PRO OXT  O  N N 292 
PRO H    H  N N 293 
PRO HA   H  N N 294 
PRO HB2  H  N N 295 
PRO HB3  H  N N 296 
PRO HG2  H  N N 297 
PRO HG3  H  N N 298 
PRO HD2  H  N N 299 
PRO HD3  H  N N 300 
PRO HXT  H  N N 301 
SER N    N  N N 302 
SER CA   C  N S 303 
SER C    C  N N 304 
SER O    O  N N 305 
SER CB   C  N N 306 
SER OG   O  N N 307 
SER OXT  O  N N 308 
SER H    H  N N 309 
SER H2   H  N N 310 
SER HA   H  N N 311 
SER HB2  H  N N 312 
SER HB3  H  N N 313 
SER HG   H  N N 314 
SER HXT  H  N N 315 
THR N    N  N N 316 
THR CA   C  N S 317 
THR C    C  N N 318 
THR O    O  N N 319 
THR CB   C  N R 320 
THR OG1  O  N N 321 
THR CG2  C  N N 322 
THR OXT  O  N N 323 
THR H    H  N N 324 
THR H2   H  N N 325 
THR HA   H  N N 326 
THR HB   H  N N 327 
THR HG1  H  N N 328 
THR HG21 H  N N 329 
THR HG22 H  N N 330 
THR HG23 H  N N 331 
THR HXT  H  N N 332 
TPO N    N  N N 333 
TPO CA   C  N S 334 
TPO CB   C  N R 335 
TPO CG2  C  N N 336 
TPO OG1  O  N N 337 
TPO P    P  N N 338 
TPO O1P  O  N N 339 
TPO O2P  O  N N 340 
TPO O3P  O  N N 341 
TPO C    C  N N 342 
TPO O    O  N N 343 
TPO OXT  O  N N 344 
TPO H    H  N N 345 
TPO H2   H  N N 346 
TPO HA   H  N N 347 
TPO HB   H  N N 348 
TPO HG21 H  N N 349 
TPO HG22 H  N N 350 
TPO HG23 H  N N 351 
TPO HOP2 H  N N 352 
TPO HOP3 H  N N 353 
TPO HXT  H  N N 354 
TRP N    N  N N 355 
TRP CA   C  N S 356 
TRP C    C  N N 357 
TRP O    O  N N 358 
TRP CB   C  N N 359 
TRP CG   C  Y N 360 
TRP CD1  C  Y N 361 
TRP CD2  C  Y N 362 
TRP NE1  N  Y N 363 
TRP CE2  C  Y N 364 
TRP CE3  C  Y N 365 
TRP CZ2  C  Y N 366 
TRP CZ3  C  Y N 367 
TRP CH2  C  Y N 368 
TRP OXT  O  N N 369 
TRP H    H  N N 370 
TRP H2   H  N N 371 
TRP HA   H  N N 372 
TRP HB2  H  N N 373 
TRP HB3  H  N N 374 
TRP HD1  H  N N 375 
TRP HE1  H  N N 376 
TRP HE3  H  N N 377 
TRP HZ2  H  N N 378 
TRP HZ3  H  N N 379 
TRP HH2  H  N N 380 
TRP HXT  H  N N 381 
TYR N    N  N N 382 
TYR CA   C  N S 383 
TYR C    C  N N 384 
TYR O    O  N N 385 
TYR CB   C  N N 386 
TYR CG   C  Y N 387 
TYR CD1  C  Y N 388 
TYR CD2  C  Y N 389 
TYR CE1  C  Y N 390 
TYR CE2  C  Y N 391 
TYR CZ   C  Y N 392 
TYR OH   O  N N 393 
TYR OXT  O  N N 394 
TYR H    H  N N 395 
TYR H2   H  N N 396 
TYR HA   H  N N 397 
TYR HB2  H  N N 398 
TYR HB3  H  N N 399 
TYR HD1  H  N N 400 
TYR HD2  H  N N 401 
TYR HE1  H  N N 402 
TYR HE2  H  N N 403 
TYR HH   H  N N 404 
TYR HXT  H  N N 405 
VAL N    N  N N 406 
VAL CA   C  N S 407 
VAL C    C  N N 408 
VAL O    O  N N 409 
VAL CB   C  N N 410 
VAL CG1  C  N N 411 
VAL CG2  C  N N 412 
VAL OXT  O  N N 413 
VAL H    H  N N 414 
VAL H2   H  N N 415 
VAL HA   H  N N 416 
VAL HB   H  N N 417 
VAL HG11 H  N N 418 
VAL HG12 H  N N 419 
VAL HG13 H  N N 420 
VAL HG21 H  N N 421 
VAL HG22 H  N N 422 
VAL HG23 H  N N 423 
VAL HXT  H  N N 424 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HGQ O1  C1   doub N N 129 
HGQ N1  C1   sing N N 130 
HGQ N1  C5   sing N N 131 
HGQ C1  C2   sing N N 132 
HGQ C5  C4   doub N N 133 
HGQ C2  C3   doub N N 134 
HGQ C4  C3   sing N N 135 
HGQ C3  BR1  sing N N 136 
HGQ C4  H1   sing N N 137 
HGQ C5  H2   sing N N 138 
HGQ N1  H3   sing N N 139 
HGQ C2  H4   sing N N 140 
HIS N   CA   sing N N 141 
HIS N   H    sing N N 142 
HIS N   H2   sing N N 143 
HIS CA  C    sing N N 144 
HIS CA  CB   sing N N 145 
HIS CA  HA   sing N N 146 
HIS C   O    doub N N 147 
HIS C   OXT  sing N N 148 
HIS CB  CG   sing N N 149 
HIS CB  HB2  sing N N 150 
HIS CB  HB3  sing N N 151 
HIS CG  ND1  sing Y N 152 
HIS CG  CD2  doub Y N 153 
HIS ND1 CE1  doub Y N 154 
HIS ND1 HD1  sing N N 155 
HIS CD2 NE2  sing Y N 156 
HIS CD2 HD2  sing N N 157 
HIS CE1 NE2  sing Y N 158 
HIS CE1 HE1  sing N N 159 
HIS NE2 HE2  sing N N 160 
HIS OXT HXT  sing N N 161 
HOH O   H1   sing N N 162 
HOH O   H2   sing N N 163 
ILE N   CA   sing N N 164 
ILE N   H    sing N N 165 
ILE N   H2   sing N N 166 
ILE CA  C    sing N N 167 
ILE CA  CB   sing N N 168 
ILE CA  HA   sing N N 169 
ILE C   O    doub N N 170 
ILE C   OXT  sing N N 171 
ILE CB  CG1  sing N N 172 
ILE CB  CG2  sing N N 173 
ILE CB  HB   sing N N 174 
ILE CG1 CD1  sing N N 175 
ILE CG1 HG12 sing N N 176 
ILE CG1 HG13 sing N N 177 
ILE CG2 HG21 sing N N 178 
ILE CG2 HG22 sing N N 179 
ILE CG2 HG23 sing N N 180 
ILE CD1 HD11 sing N N 181 
ILE CD1 HD12 sing N N 182 
ILE CD1 HD13 sing N N 183 
ILE OXT HXT  sing N N 184 
LEU N   CA   sing N N 185 
LEU N   H    sing N N 186 
LEU N   H2   sing N N 187 
LEU CA  C    sing N N 188 
LEU CA  CB   sing N N 189 
LEU CA  HA   sing N N 190 
LEU C   O    doub N N 191 
LEU C   OXT  sing N N 192 
LEU CB  CG   sing N N 193 
LEU CB  HB2  sing N N 194 
LEU CB  HB3  sing N N 195 
LEU CG  CD1  sing N N 196 
LEU CG  CD2  sing N N 197 
LEU CG  HG   sing N N 198 
LEU CD1 HD11 sing N N 199 
LEU CD1 HD12 sing N N 200 
LEU CD1 HD13 sing N N 201 
LEU CD2 HD21 sing N N 202 
LEU CD2 HD22 sing N N 203 
LEU CD2 HD23 sing N N 204 
LEU OXT HXT  sing N N 205 
LYS N   CA   sing N N 206 
LYS N   H    sing N N 207 
LYS N   H2   sing N N 208 
LYS CA  C    sing N N 209 
LYS CA  CB   sing N N 210 
LYS CA  HA   sing N N 211 
LYS C   O    doub N N 212 
LYS C   OXT  sing N N 213 
LYS CB  CG   sing N N 214 
LYS CB  HB2  sing N N 215 
LYS CB  HB3  sing N N 216 
LYS CG  CD   sing N N 217 
LYS CG  HG2  sing N N 218 
LYS CG  HG3  sing N N 219 
LYS CD  CE   sing N N 220 
LYS CD  HD2  sing N N 221 
LYS CD  HD3  sing N N 222 
LYS CE  NZ   sing N N 223 
LYS CE  HE2  sing N N 224 
LYS CE  HE3  sing N N 225 
LYS NZ  HZ1  sing N N 226 
LYS NZ  HZ2  sing N N 227 
LYS NZ  HZ3  sing N N 228 
LYS OXT HXT  sing N N 229 
MET N   CA   sing N N 230 
MET N   H    sing N N 231 
MET N   H2   sing N N 232 
MET CA  C    sing N N 233 
MET CA  CB   sing N N 234 
MET CA  HA   sing N N 235 
MET C   O    doub N N 236 
MET C   OXT  sing N N 237 
MET CB  CG   sing N N 238 
MET CB  HB2  sing N N 239 
MET CB  HB3  sing N N 240 
MET CG  SD   sing N N 241 
MET CG  HG2  sing N N 242 
MET CG  HG3  sing N N 243 
MET SD  CE   sing N N 244 
MET CE  HE1  sing N N 245 
MET CE  HE2  sing N N 246 
MET CE  HE3  sing N N 247 
MET OXT HXT  sing N N 248 
PHE N   CA   sing N N 249 
PHE N   H    sing N N 250 
PHE N   H2   sing N N 251 
PHE CA  C    sing N N 252 
PHE CA  CB   sing N N 253 
PHE CA  HA   sing N N 254 
PHE C   O    doub N N 255 
PHE C   OXT  sing N N 256 
PHE CB  CG   sing N N 257 
PHE CB  HB2  sing N N 258 
PHE CB  HB3  sing N N 259 
PHE CG  CD1  doub Y N 260 
PHE CG  CD2  sing Y N 261 
PHE CD1 CE1  sing Y N 262 
PHE CD1 HD1  sing N N 263 
PHE CD2 CE2  doub Y N 264 
PHE CD2 HD2  sing N N 265 
PHE CE1 CZ   doub Y N 266 
PHE CE1 HE1  sing N N 267 
PHE CE2 CZ   sing Y N 268 
PHE CE2 HE2  sing N N 269 
PHE CZ  HZ   sing N N 270 
PHE OXT HXT  sing N N 271 
PRO N   CA   sing N N 272 
PRO N   CD   sing N N 273 
PRO N   H    sing N N 274 
PRO CA  C    sing N N 275 
PRO CA  CB   sing N N 276 
PRO CA  HA   sing N N 277 
PRO C   O    doub N N 278 
PRO C   OXT  sing N N 279 
PRO CB  CG   sing N N 280 
PRO CB  HB2  sing N N 281 
PRO CB  HB3  sing N N 282 
PRO CG  CD   sing N N 283 
PRO CG  HG2  sing N N 284 
PRO CG  HG3  sing N N 285 
PRO CD  HD2  sing N N 286 
PRO CD  HD3  sing N N 287 
PRO OXT HXT  sing N N 288 
SER N   CA   sing N N 289 
SER N   H    sing N N 290 
SER N   H2   sing N N 291 
SER CA  C    sing N N 292 
SER CA  CB   sing N N 293 
SER CA  HA   sing N N 294 
SER C   O    doub N N 295 
SER C   OXT  sing N N 296 
SER CB  OG   sing N N 297 
SER CB  HB2  sing N N 298 
SER CB  HB3  sing N N 299 
SER OG  HG   sing N N 300 
SER OXT HXT  sing N N 301 
THR N   CA   sing N N 302 
THR N   H    sing N N 303 
THR N   H2   sing N N 304 
THR CA  C    sing N N 305 
THR CA  CB   sing N N 306 
THR CA  HA   sing N N 307 
THR C   O    doub N N 308 
THR C   OXT  sing N N 309 
THR CB  OG1  sing N N 310 
THR CB  CG2  sing N N 311 
THR CB  HB   sing N N 312 
THR OG1 HG1  sing N N 313 
THR CG2 HG21 sing N N 314 
THR CG2 HG22 sing N N 315 
THR CG2 HG23 sing N N 316 
THR OXT HXT  sing N N 317 
TPO N   CA   sing N N 318 
TPO N   H    sing N N 319 
TPO N   H2   sing N N 320 
TPO CA  CB   sing N N 321 
TPO CA  C    sing N N 322 
TPO CA  HA   sing N N 323 
TPO CB  CG2  sing N N 324 
TPO CB  OG1  sing N N 325 
TPO CB  HB   sing N N 326 
TPO CG2 HG21 sing N N 327 
TPO CG2 HG22 sing N N 328 
TPO CG2 HG23 sing N N 329 
TPO OG1 P    sing N N 330 
TPO P   O1P  doub N N 331 
TPO P   O2P  sing N N 332 
TPO P   O3P  sing N N 333 
TPO O2P HOP2 sing N N 334 
TPO O3P HOP3 sing N N 335 
TPO C   O    doub N N 336 
TPO C   OXT  sing N N 337 
TPO OXT HXT  sing N N 338 
TRP N   CA   sing N N 339 
TRP N   H    sing N N 340 
TRP N   H2   sing N N 341 
TRP CA  C    sing N N 342 
TRP CA  CB   sing N N 343 
TRP CA  HA   sing N N 344 
TRP C   O    doub N N 345 
TRP C   OXT  sing N N 346 
TRP CB  CG   sing N N 347 
TRP CB  HB2  sing N N 348 
TRP CB  HB3  sing N N 349 
TRP CG  CD1  doub Y N 350 
TRP CG  CD2  sing Y N 351 
TRP CD1 NE1  sing Y N 352 
TRP CD1 HD1  sing N N 353 
TRP CD2 CE2  doub Y N 354 
TRP CD2 CE3  sing Y N 355 
TRP NE1 CE2  sing Y N 356 
TRP NE1 HE1  sing N N 357 
TRP CE2 CZ2  sing Y N 358 
TRP CE3 CZ3  doub Y N 359 
TRP CE3 HE3  sing N N 360 
TRP CZ2 CH2  doub Y N 361 
TRP CZ2 HZ2  sing N N 362 
TRP CZ3 CH2  sing Y N 363 
TRP CZ3 HZ3  sing N N 364 
TRP CH2 HH2  sing N N 365 
TRP OXT HXT  sing N N 366 
TYR N   CA   sing N N 367 
TYR N   H    sing N N 368 
TYR N   H2   sing N N 369 
TYR CA  C    sing N N 370 
TYR CA  CB   sing N N 371 
TYR CA  HA   sing N N 372 
TYR C   O    doub N N 373 
TYR C   OXT  sing N N 374 
TYR CB  CG   sing N N 375 
TYR CB  HB2  sing N N 376 
TYR CB  HB3  sing N N 377 
TYR CG  CD1  doub Y N 378 
TYR CG  CD2  sing Y N 379 
TYR CD1 CE1  sing Y N 380 
TYR CD1 HD1  sing N N 381 
TYR CD2 CE2  doub Y N 382 
TYR CD2 HD2  sing N N 383 
TYR CE1 CZ   doub Y N 384 
TYR CE1 HE1  sing N N 385 
TYR CE2 CZ   sing Y N 386 
TYR CE2 HE2  sing N N 387 
TYR CZ  OH   sing N N 388 
TYR OH  HH   sing N N 389 
TYR OXT HXT  sing N N 390 
VAL N   CA   sing N N 391 
VAL N   H    sing N N 392 
VAL N   H2   sing N N 393 
VAL CA  C    sing N N 394 
VAL CA  CB   sing N N 395 
VAL CA  HA   sing N N 396 
VAL C   O    doub N N 397 
VAL C   OXT  sing N N 398 
VAL CB  CG1  sing N N 399 
VAL CB  CG2  sing N N 400 
VAL CB  HB   sing N N 401 
VAL CG1 HG11 sing N N 402 
VAL CG1 HG12 sing N N 403 
VAL CG1 HG13 sing N N 404 
VAL CG2 HG21 sing N N 405 
VAL CG2 HG22 sing N N 406 
VAL CG2 HG23 sing N N 407 
VAL OXT HXT  sing N N 408 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ET7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013481 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007478 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006759 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 -0.0527  
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P  15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLY A 1 1   ? -19.571 -6.597  25.317  1   74.34  ? -3  GLY A N   1 
ATOM   2    C  CA  . GLY A 1 1   ? -20.911 -6.039  25.208  1   73.38  ? -3  GLY A CA  1 
ATOM   3    C  C   . GLY A 1 1   ? -21.727 -6.312  26.469  1   77.13  ? -3  GLY A C   1 
ATOM   4    O  O   . GLY A 1 1   ? -21.947 -5.399  27.267  1   78.47  ? -3  GLY A O   1 
ATOM   5    N  N   . PRO A 1 2   ? -22.235 -7.556  26.661  1   74.81  ? -2  PRO A N   1 
ATOM   6    C  CA  . PRO A 1 2   ? -22.82  -7.979  27.942  1   71.72  ? -2  PRO A CA  1 
ATOM   7    C  C   . PRO A 1 2   ? -21.893 -7.992  29.159  1   64.13  ? -2  PRO A C   1 
ATOM   8    O  O   . PRO A 1 2   ? -22.269 -7.515  30.227  1   58.17  ? -2  PRO A O   1 
ATOM   9    C  CB  . PRO A 1 2   ? -23.31  -9.41   27.652  1   69.46  ? -2  PRO A CB  1 
ATOM   10   C  CG  . PRO A 1 2   ? -23.448 -9.483  26.163  1   72.19  ? -2  PRO A CG  1 
ATOM   11   C  CD  . PRO A 1 2   ? -22.387 -8.574  25.608  1   72.69  ? -2  PRO A CD  1 
ATOM   12   N  N   . GLY A 1 3   ? -20.693 -8.564  28.998  1   59.29  ? -1  GLY A N   1 
ATOM   13   C  CA  . GLY A 1 3   ? -19.774 -8.763  30.107  1   58.41  ? -1  GLY A CA  1 
ATOM   14   C  C   . GLY A 1 3   ? -18.827 -7.599  30.407  1   53.69  ? -1  GLY A C   1 
ATOM   15   O  O   . GLY A 1 3   ? -18.731 -6.642  29.636  1   48.24  ? -1  GLY A O   1 
ATOM   16   N  N   . SER A 1 4   ? -18.164 -7.7    31.568  1   56.06  ? 0   SER A N   1 
ATOM   17   C  CA  . SER A 1 4   ? -17.01  -6.888  31.935  1   56     ? 0   SER A CA  1 
ATOM   18   C  C   . SER A 1 4   ? -16.003 -7.775  32.671  1   51.51  ? 0   SER A C   1 
ATOM   19   O  O   . SER A 1 4   ? -16.343 -8.885  33.097  1   51.24  ? 0   SER A O   1 
ATOM   20   C  CB  . SER A 1 4   ? -17.415 -5.694  32.798  1   53.85  ? 0   SER A CB  1 
ATOM   21   O  OG  . SER A 1 4   ? -17.859 -6.121  34.075  1   53.51  ? 0   SER A OG  1 
ATOM   22   N  N   . MET A 1 5   ? -14.777 -7.266  32.851  1   47.07  ? 1   MET A N   1 
ATOM   23   C  CA  . MET A 1 5   ? -13.671 -8.081  33.331  1   42.09  ? 1   MET A CA  1 
ATOM   24   C  C   . MET A 1 5   ? -13.783 -8.402  34.817  1   38.31  ? 1   MET A C   1 
ATOM   25   O  O   . MET A 1 5   ? -13.233 -9.397  35.279  1   41.22  ? 1   MET A O   1 
ATOM   26   C  CB  . MET A 1 5   ? -12.343 -7.396  33.026  1   39.55  ? 1   MET A CB  1 
ATOM   27   C  CG  . MET A 1 5   ? -12.049 -7.369  31.533  1   41.41  ? 1   MET A CG  1 
ATOM   28   S  SD  . MET A 1 5   ? -12.182 -8.998  30.749  1   43.65  ? 1   MET A SD  1 
ATOM   29   C  CE  . MET A 1 5   ? -10.993 -9.906  31.725  1   41.21  ? 1   MET A CE  1 
ATOM   30   N  N   . GLU A 1 6   ? -14.56  -7.588  35.536  1   38.75  ? 2   GLU A N   1 
ATOM   31   C  CA  . GLU A 1 6   ? -14.796 -7.797  36.951  1   38.68  ? 2   GLU A CA  1 
ATOM   32   C  C   . GLU A 1 6   ? -15.524 -9.104  37.279  1   33.66  ? 2   GLU A C   1 
ATOM   33   O  O   . GLU A 1 6   ? -15.383 -9.608  38.387  1   32.74  ? 2   GLU A O   1 
ATOM   34   C  CB  . GLU A 1 6   ? -15.576 -6.593  37.501  1   44.25  ? 2   GLU A CB  1 
ATOM   35   C  CG  . GLU A 1 6   ? -15.769 -6.603  39.008  1   52.87  ? 2   GLU A CG  1 
ATOM   36   C  CD  . GLU A 1 6   ? -14.529 -6.866  39.85   1   61.53  ? 2   GLU A CD  1 
ATOM   37   O  OE1 . GLU A 1 6   ? -13.455 -6.301  39.537  1   65.65  ? 2   GLU A OE1 1 
ATOM   38   O  OE2 . GLU A 1 6   ? -14.643 -7.618  40.846  1   68.85  ? 2   GLU A OE2 1 
ATOM   39   N  N   . ASN A 1 7   ? -16.282 -9.668  36.332  1   30.33  ? 3   ASN A N   1 
ATOM   40   C  CA  . ASN A 1 7   ? -16.928 -10.954 36.561  1   31.75  ? 3   ASN A CA  1 
ATOM   41   C  C   . ASN A 1 7   ? -16.061 -12.17  36.253  1   29.17  ? 3   ASN A C   1 
ATOM   42   O  O   . ASN A 1 7   ? -16.488 -13.3   36.483  1   31.1   ? 3   ASN A O   1 
ATOM   43   C  CB  . ASN A 1 7   ? -18.223 -11.068 35.766  1   33.49  ? 3   ASN A CB  1 
ATOM   44   C  CG  . ASN A 1 7   ? -19.27  -10.108 36.256  1   35.38  ? 3   ASN A CG  1 
ATOM   45   O  OD1 . ASN A 1 7   ? -20.065 -9.579  35.47   1   39.89  ? 3   ASN A OD1 1 
ATOM   46   N  ND2 . ASN A 1 7   ? -19.33  -9.897  37.57   1   33.89  ? 3   ASN A ND2 1 
ATOM   47   N  N   . PHE A 1 8   ? -14.85  -11.944 35.733  1   27.43  ? 4   PHE A N   1 
ATOM   48   C  CA  . PHE A 1 8   ? -13.961 -13.046 35.416  1   27.15  ? 4   PHE A CA  1 
ATOM   49   C  C   . PHE A 1 8   ? -12.824 -13.156 36.428  1   29.23  ? 4   PHE A C   1 
ATOM   50   O  O   . PHE A 1 8   ? -12.257 -12.157 36.869  1   31.56  ? 4   PHE A O   1 
ATOM   51   C  CB  . PHE A 1 8   ? -13.442 -12.915 33.992  1   28.37  ? 4   PHE A CB  1 
ATOM   52   C  CG  . PHE A 1 8   ? -14.524 -13.091 32.958  1   27.95  ? 4   PHE A CG  1 
ATOM   53   C  CD1 . PHE A 1 8   ? -15.032 -14.343 32.675  1   27.75  ? 4   PHE A CD1 1 
ATOM   54   C  CD2 . PHE A 1 8   ? -15.055 -11.992 32.287  1   28.78  ? 4   PHE A CD2 1 
ATOM   55   C  CE1 . PHE A 1 8   ? -16.046 -14.502 31.72   1   30.54  ? 4   PHE A CE1 1 
ATOM   56   C  CE2 . PHE A 1 8   ? -16.072 -12.152 31.35   1   30.05  ? 4   PHE A CE2 1 
ATOM   57   C  CZ  . PHE A 1 8   ? -16.564 -13.404 31.072  1   28.9   ? 4   PHE A CZ  1 
ATOM   58   N  N   . GLN A 1 9   ? -12.543 -14.403 36.819  1   30.47  ? 5   GLN A N   1 
ATOM   59   C  CA  . GLN A 1 9   ? -11.426 -14.74  37.681  1   30.48  ? 5   GLN A CA  1 
ATOM   60   C  C   . GLN A 1 9   ? -10.456 -15.594 36.872  1   30.03  ? 5   GLN A C   1 
ATOM   61   O  O   . GLN A 1 9   ? -10.794 -16.711 36.481  1   31.72  ? 5   GLN A O   1 
ATOM   62   C  CB  . GLN A 1 9   ? -11.925 -15.495 38.919  1   32.75  ? 5   GLN A CB  1 
ATOM   63   C  CG  . GLN A 1 9   ? -10.823 -15.984 39.85   1   35.14  ? 5   GLN A CG  1 
ATOM   64   C  CD  . GLN A 1 9   ? -10.017 -14.858 40.443  1   37.12  ? 5   GLN A CD  1 
ATOM   65   O  OE1 . GLN A 1 9   ? -10.512 -14.021 41.211  1   39.9   ? 5   GLN A OE1 1 
ATOM   66   N  NE2 . GLN A 1 9   ? -8.75   -14.815 40.087  1   37.32  ? 5   GLN A NE2 1 
ATOM   67   N  N   . LYS A 1 10  ? -9.268  -15.041 36.594  1   29.16  ? 6   LYS A N   1 
ATOM   68   C  CA  . LYS A 1 10  ? -8.243  -15.745 35.848  1   29.77  ? 6   LYS A CA  1 
ATOM   69   C  C   . LYS A 1 10  ? -7.777  -16.94  36.674  1   28.74  ? 6   LYS A C   1 
ATOM   70   O  O   . LYS A 1 10  ? -7.696  -16.858 37.89   1   24.24  ? 6   LYS A O   1 
ATOM   71   C  CB  . LYS A 1 10  ? -7.088  -14.803 35.483  1   31.54  ? 6   LYS A CB  1 
ATOM   72   C  CG  . LYS A 1 10  ? -7.484  -13.713 34.476  1   35.62  ? 6   LYS A CG  1 
ATOM   73   C  CD  . LYS A 1 10  ? -6.277  -12.874 34.015  1   42.26  ? 6   LYS A CD  1 
ATOM   74   C  CE  . LYS A 1 10  ? -6.568  -11.935 32.844  1   46.88  ? 6   LYS A CE  1 
ATOM   75   N  NZ  . LYS A 1 10  ? -7.127  -10.64  33.31   1   51.5   ? 6   LYS A NZ  1 
ATOM   76   N  N   . VAL A 1 11  ? -7.544  -18.072 36.001  1   34.2   ? 7   VAL A N   1 
ATOM   77   C  CA  . VAL A 1 11  ? -7.173  -19.31  36.668  1   34.61  ? 7   VAL A CA  1 
ATOM   78   C  C   . VAL A 1 11  ? -5.712  -19.643 36.389  1   33.58  ? 7   VAL A C   1 
ATOM   79   O  O   . VAL A 1 11  ? -4.96   -19.933 37.309  1   34.74  ? 7   VAL A O   1 
ATOM   80   C  CB  . VAL A 1 11  ? -8.11   -20.461 36.246  1   37.44  ? 7   VAL A CB  1 
ATOM   81   C  CG1 . VAL A 1 11  ? -7.624  -21.793 36.812  1   37.86  ? 7   VAL A CG1 1 
ATOM   82   C  CG2 . VAL A 1 11  ? -9.551  -20.177 36.668  1   38.53  ? 7   VAL A CG2 1 
ATOM   83   N  N   . GLU A 1 12  ? -5.328  -19.601 35.112  1   36.05  ? 8   GLU A N   1 
ATOM   84   C  CA  . GLU A 1 12  ? -3.954  -19.843 34.711  1   39.24  ? 8   GLU A CA  1 
ATOM   85   C  C   . GLU A 1 12  ? -3.779  -19.447 33.247  1   41.25  ? 8   GLU A C   1 
ATOM   86   O  O   . GLU A 1 12  ? -4.76   -19.326 32.512  1   38.65  ? 8   GLU A O   1 
ATOM   87   C  CB  . GLU A 1 12  ? -3.588  -21.323 34.892  1   42.8   ? 8   GLU A CB  1 
ATOM   88   C  CG  . GLU A 1 12  ? -4.395  -22.253 33.999  1   46.75  ? 8   GLU A CG  1 
ATOM   89   C  CD  . GLU A 1 12  ? -4.144  -23.729 34.211  1   48.46  ? 8   GLU A CD  1 
ATOM   90   O  OE1 . GLU A 1 12  ? -4.338  -24.214 35.349  1   54.26  ? 8   GLU A OE1 1 
ATOM   91   O  OE2 . GLU A 1 12  ? -3.772  -24.406 33.227  1   46.52  ? 8   GLU A OE2 1 
ATOM   92   N  N   . LYS A 1 13  ? -2.518  -19.255 32.843  1   41.44  ? 9   LYS A N   1 
ATOM   93   C  CA  . LYS A 1 13  ? -2.171  -19.003 31.458  1   41.31  ? 9   LYS A CA  1 
ATOM   94   C  C   . LYS A 1 13  ? -2.255  -20.319 30.688  1   41.63  ? 9   LYS A C   1 
ATOM   95   O  O   . LYS A 1 13  ? -1.846  -21.357 31.195  1   41.35  ? 9   LYS A O   1 
ATOM   96   C  CB  . LYS A 1 13  ? -0.767  -18.395 31.391  1   44.75  ? 9   LYS A CB  1 
ATOM   97   C  CG  . LYS A 1 13  ? -0.235  -18.138 29.986  1   50.5   ? 9   LYS A CG  1 
ATOM   98   C  CD  . LYS A 1 13  ? 1.167   -17.571 30.043  1   54.08  ? 9   LYS A CD  1 
ATOM   99   C  CE  . LYS A 1 13  ? 1.72    -17.262 28.682  1   59.02  ? 9   LYS A CE  1 
ATOM   100  N  NZ  . LYS A 1 13  ? 3.031   -16.578 28.789  1   65.83  ? 9   LYS A NZ  1 
ATOM   101  N  N   . ILE A 1 14  ? -2.827  -20.286 29.48   1   38.92  ? 10  ILE A N   1 
ATOM   102  C  CA  . ILE A 1 14  ? -2.988  -21.508 28.714  1   40.04  ? 10  ILE A CA  1 
ATOM   103  C  C   . ILE A 1 14  ? -2.29   -21.447 27.363  1   37.44  ? 10  ILE A C   1 
ATOM   104  O  O   . ILE A 1 14  ? -2.178  -22.467 26.694  1   42.33  ? 10  ILE A O   1 
ATOM   105  C  CB  . ILE A 1 14  ? -4.484  -21.918 28.57   1   43.06  ? 10  ILE A CB  1 
ATOM   106  C  CG1 . ILE A 1 14  ? -5.327  -20.881 27.826  1   44.94  ? 10  ILE A CG1 1 
ATOM   107  C  CG2 . ILE A 1 14  ? -5.086  -22.225 29.943  1   46.6   ? 10  ILE A CG2 1 
ATOM   108  C  CD1 . ILE A 1 14  ? -6.825  -21.274 27.708  1   45.57  ? 10  ILE A CD1 1 
ATOM   109  N  N   . GLY A 1 15  ? -1.792  -20.272 26.98   1   39.23  ? 11  GLY A N   1 
ATOM   110  C  CA  . GLY A 1 15  ? -1.086  -20.15  25.716  1   45.52  ? 11  GLY A CA  1 
ATOM   111  C  C   . GLY A 1 15  ? -0.842  -18.707 25.291  1   47.63  ? 11  GLY A C   1 
ATOM   112  O  O   . GLY A 1 15  ? -1.057  -17.777 26.072  1   44.97  ? 11  GLY A O   1 
ATOM   113  N  N   . GLU A 1 16  ? -0.388  -18.537 24.045  1   52.76  ? 12  GLU A N   1 
ATOM   114  C  CA  . GLU A 1 16  ? -0.299  -17.214 23.452  1   62.06  ? 12  GLU A CA  1 
ATOM   115  C  C   . GLU A 1 16  ? -0.179  -17.227 21.933  1   69.94  ? 12  GLU A C   1 
ATOM   116  O  O   . GLU A 1 16  ? 0.601   -17.996 21.377  1   66.5   ? 12  GLU A O   1 
ATOM   117  C  CB  . GLU A 1 16  ? 0.88    -16.449 24.039  1   63.54  ? 12  GLU A CB  1 
ATOM   118  C  CG  . GLU A 1 16  ? 2.197   -17.175 23.903  1   66.5   ? 12  GLU A CG  1 
ATOM   119  C  CD  . GLU A 1 16  ? 3.204   -16.714 24.928  1   68.71  ? 12  GLU A CD  1 
ATOM   120  O  OE1 . GLU A 1 16  ? 3.299   -15.481 25.124  1   64.75  ? 12  GLU A OE1 1 
ATOM   121  O  OE2 . GLU A 1 16  ? 3.889   -17.572 25.536  1   65.16  ? 12  GLU A OE2 1 
ATOM   122  N  N   . GLY A 1 17  ? -0.989  -16.379 21.284  1   81.39  ? 13  GLY A N   1 
ATOM   123  C  CA  . GLY A 1 17  ? -0.757  -15.95  19.915  1   85.77  ? 13  GLY A CA  1 
ATOM   124  C  C   . GLY A 1 17  ? -0.022  -14.611 19.924  1   93.3   ? 13  GLY A C   1 
ATOM   125  O  O   . GLY A 1 17  ? 0.518   -14.218 20.957  1   92.04  ? 13  GLY A O   1 
ATOM   126  N  N   . THR A 1 18  ? 0.009   -13.924 18.773  1   93.62  ? 14  THR A N   1 
ATOM   127  C  CA  . THR A 1 18  ? 0.528   -12.565 18.72   1   88.99  ? 14  THR A CA  1 
ATOM   128  C  C   . THR A 1 18  ? -0.499  -11.64  19.366  1   94.99  ? 14  THR A C   1 
ATOM   129  O  O   . THR A 1 18  ? -1.659  -12.017 19.542  1   82.34  ? 14  THR A O   1 
ATOM   130  C  CB  . THR A 1 18  ? 0.873   -12.148 17.292  1   79.94  ? 14  THR A CB  1 
ATOM   131  O  OG1 . THR A 1 18  ? 1.638   -13.184 16.691  1   74.95  ? 14  THR A OG1 1 
ATOM   132  C  CG2 . THR A 1 18  ? 1.658   -10.831 17.233  1   73.09  ? 14  THR A CG2 1 
ATOM   133  N  N   . TYR A 1 19  ? -0.04   -10.44  19.754  1   100.53 ? 15  TYR A N   1 
ATOM   134  C  CA  . TYR A 1 19  ? -0.878  -9.41   20.35   1   95.92  ? 15  TYR A CA  1 
ATOM   135  C  C   . TYR A 1 19  ? -1.262  -9.752  21.788  1   85.07  ? 15  TYR A C   1 
ATOM   136  O  O   . TYR A 1 19  ? -1.645  -8.858  22.546  1   74.14  ? 15  TYR A O   1 
ATOM   137  C  CB  . TYR A 1 19  ? -2.108  -9.115  19.47   1   93.98  ? 15  TYR A CB  1 
ATOM   138  C  CG  . TYR A 1 19  ? -1.733  -8.768  18.047  1   98.61  ? 15  TYR A CG  1 
ATOM   139  C  CD1 . TYR A 1 19  ? -1.054  -7.591  17.75   1   97.08  ? 15  TYR A CD1 1 
ATOM   140  C  CD2 . TYR A 1 19  ? -2.036  -9.627  16.997  1   101.42 ? 15  TYR A CD2 1 
ATOM   141  C  CE1 . TYR A 1 19  ? -0.699  -7.272  16.443  1   96.73  ? 15  TYR A CE1 1 
ATOM   142  C  CE2 . TYR A 1 19  ? -1.68   -9.323  15.688  1   101.97 ? 15  TYR A CE2 1 
ATOM   143  C  CZ  . TYR A 1 19  ? -1.015  -8.143  15.414  1   101.58 ? 15  TYR A CZ  1 
ATOM   144  O  OH  . TYR A 1 19  ? -0.681  -7.855  14.114  1   104.44 ? 15  TYR A OH  1 
ATOM   145  N  N   . GLY A 1 20  ? -1.146  -11.037 22.167  1   71.8   ? 16  GLY A N   1 
ATOM   146  C  CA  . GLY A 1 20  ? -0.904  -11.369 23.556  1   65.92  ? 16  GLY A CA  1 
ATOM   147  C  C   . GLY A 1 20  ? -1.178  -12.808 23.97   1   55.85  ? 16  GLY A C   1 
ATOM   148  O  O   . GLY A 1 20  ? -0.937  -13.75  23.226  1   48.5   ? 16  GLY A O   1 
ATOM   149  N  N   . VAL A 1 21  ? -1.684  -12.923 25.194  1   59.74  ? 17  VAL A N   1 
ATOM   150  C  CA  . VAL A 1 21  ? -1.709  -14.155 25.957  1   57.97  ? 17  VAL A CA  1 
ATOM   151  C  C   . VAL A 1 21  ? -3.149  -14.657 26.031  1   49.89  ? 17  VAL A C   1 
ATOM   152  O  O   . VAL A 1 21  ? -4.082  -13.873 25.898  1   54.21  ? 17  VAL A O   1 
ATOM   153  C  CB  . VAL A 1 21  ? -1.094  -13.878 27.367  1   57.34  ? 17  VAL A CB  1 
ATOM   154  C  CG1 . VAL A 1 21  ? -1.771  -12.701 28.068  1   56.83  ? 17  VAL A CG1 1 
ATOM   155  C  CG2 . VAL A 1 21  ? -1.144  -15.105 28.263  1   62.33  ? 17  VAL A CG2 1 
ATOM   156  N  N   . VAL A 1 22  ? -3.308  -15.968 26.239  1   40.93  ? 18  VAL A N   1 
ATOM   157  C  CA  . VAL A 1 22  ? -4.599  -16.577 26.499  1   35.92  ? 18  VAL A CA  1 
ATOM   158  C  C   . VAL A 1 22  ? -4.628  -17.112 27.931  1   34.61  ? 18  VAL A C   1 
ATOM   159  O  O   . VAL A 1 22  ? -3.735  -17.848 28.334  1   33.32  ? 18  VAL A O   1 
ATOM   160  C  CB  . VAL A 1 22  ? -4.899  -17.682 25.466  1   36.72  ? 18  VAL A CB  1 
ATOM   161  C  CG1 . VAL A 1 22  ? -6.326  -18.193 25.61   1   37.56  ? 18  VAL A CG1 1 
ATOM   162  C  CG2 . VAL A 1 22  ? -4.648  -17.2   24.041  1   34     ? 18  VAL A CG2 1 
ATOM   163  N  N   . TYR A 1 23  ? -5.642  -16.699 28.7    1   33.02  ? 19  TYR A N   1 
ATOM   164  C  CA  . TYR A 1 23  ? -5.898  -17.224 30.029  1   35.94  ? 19  TYR A CA  1 
ATOM   165  C  C   . TYR A 1 23  ? -7.151  -18.093 30.065  1   37.27  ? 19  TYR A C   1 
ATOM   166  O  O   . TYR A 1 23  ? -8.128  -17.825 29.369  1   33.99  ? 19  TYR A O   1 
ATOM   167  C  CB  . TYR A 1 23  ? -6.113  -16.089 31.018  1   39.85  ? 19  TYR A CB  1 
ATOM   168  C  CG  . TYR A 1 23  ? -4.879  -15.297 31.375  1   46.1   ? 19  TYR A CG  1 
ATOM   169  C  CD1 . TYR A 1 23  ? -4.055  -15.691 32.419  1   49.5   ? 19  TYR A CD1 1 
ATOM   170  C  CD2 . TYR A 1 23  ? -4.558  -14.129 30.696  1   52.37  ? 19  TYR A CD2 1 
ATOM   171  C  CE1 . TYR A 1 23  ? -2.934  -14.951 32.776  1   55.64  ? 19  TYR A CE1 1 
ATOM   172  C  CE2 . TYR A 1 23  ? -3.436  -13.381 31.036  1   57.79  ? 19  TYR A CE2 1 
ATOM   173  C  CZ  . TYR A 1 23  ? -2.625  -13.795 32.081  1   61.11  ? 19  TYR A CZ  1 
ATOM   174  O  OH  . TYR A 1 23  ? -1.513  -13.069 32.437  1   59.31  ? 19  TYR A OH  1 
ATOM   175  N  N   . LYS A 1 24  ? -7.114  -19.121 30.913  1   35.04  ? 20  LYS A N   1 
ATOM   176  C  CA  . LYS A 1 24  ? -8.317  -19.823 31.314  1   30.46  ? 20  LYS A CA  1 
ATOM   177  C  C   . LYS A 1 24  ? -8.901  -19     32.45   1   28.92  ? 20  LYS A C   1 
ATOM   178  O  O   . LYS A 1 24  ? -8.167  -18.553 33.329  1   30.86  ? 20  LYS A O   1 
ATOM   179  C  CB  . LYS A 1 24  ? -8.002  -21.241 31.747  1   32.17  ? 20  LYS A CB  1 
ATOM   180  C  CG  . LYS A 1 24  ? -9.139  -21.975 32.435  1   33.3   ? 20  LYS A CG  1 
ATOM   181  C  CD  . LYS A 1 24  ? -8.66   -23.299 32.943  1   34.4   ? 20  LYS A CD  1 
ATOM   182  C  CE  . LYS A 1 24  ? -9.779  -24.158 33.412  1   36.73  ? 20  LYS A CE  1 
ATOM   183  N  NZ  . LYS A 1 24  ? -9.252  -25.475 33.84   1   38.1   ? 20  LYS A NZ  1 
ATOM   184  N  N   . ALA A 1 25  ? -10.218 -18.78  32.403  1   27.84  ? 21  ALA A N   1 
ATOM   185  C  CA  . ALA A 1 25  ? -10.887 -17.983 33.415  1   26.76  ? 21  ALA A CA  1 
ATOM   186  C  C   . ALA A 1 25  ? -12.256 -18.564 33.752  1   26.61  ? 21  ALA A C   1 
ATOM   187  O  O   . ALA A 1 25  ? -12.809 -19.37  32.999  1   26.81  ? 21  ALA A O   1 
ATOM   188  C  CB  . ALA A 1 25  ? -11.013 -16.548 32.947  1   26.63  ? 21  ALA A CB  1 
ATOM   189  N  N   . ARG A 1 26  ? -12.765 -18.113 34.891  1   26.14  ? 22  ARG A N   1 
ATOM   190  C  CA  . ARG A 1 26  ? -14.083 -18.586 35.35   1   26.31  ? 22  ARG A CA  1 
ATOM   191  C  C   . ARG A 1 26  ? -15.012 -17.397 35.581  1   25.66  ? 22  ARG A C   1 
ATOM   192  O  O   . ARG A 1 26  ? -14.596 -16.435 36.233  1   24.83  ? 22  ARG A O   1 
ATOM   193  C  CB  . ARG A 1 26  ? -13.946 -19.4   36.637  1   26.55  ? 22  ARG A CB  1 
ATOM   194  C  CG  . ARG A 1 26  ? -15.231 -20.13  36.994  1   27.46  ? 22  ARG A CG  1 
ATOM   195  C  CD  . ARG A 1 26  ? -15.048 -21.087 38.16   1   27.78  ? 22  ARG A CD  1 
ATOM   196  N  NE  . ARG A 1 26  ? -14.88  -22.478 37.728  1   26.94  ? 22  ARG A NE  1 
ATOM   197  C  CZ  . ARG A 1 26  ? -13.716 -23.113 37.67   1   25.7   ? 22  ARG A CZ  1 
ATOM   198  N  NH1 . ARG A 1 26  ? -13.646 -24.313 37.125  1   25.19  ? 22  ARG A NH1 1 
ATOM   199  N  NH2 . ARG A 1 26  ? -12.625 -22.55  38.158  1   25.7   ? 22  ARG A NH2 1 
ATOM   200  N  N   . ASN A 1 27  ? -16.202 -17.454 35.002  1   25.21  ? 23  ASN A N   1 
ATOM   201  C  CA  . ASN A 1 27  ? -17.233 -16.458 35.242  1   24.11  ? 23  ASN A CA  1 
ATOM   202  C  C   . ASN A 1 27  ? -17.734 -16.651 36.67   1   24.16  ? 23  ASN A C   1 
ATOM   203  O  O   . ASN A 1 27  ? -18.279 -17.702 36.991  1   24.97  ? 23  ASN A O   1 
ATOM   204  C  CB  . ASN A 1 27  ? -18.389 -16.594 34.223  1   21.3   ? 23  ASN A CB  1 
ATOM   205  C  CG  . ASN A 1 27  ? -19.459 -15.539 34.393  1   19.32  ? 23  ASN A CG  1 
ATOM   206  O  OD1 . ASN A 1 27  ? -19.868 -15.187 35.497  1   19.38  ? 23  ASN A OD1 1 
ATOM   207  N  ND2 . ASN A 1 27  ? -19.933 -14.996 33.321  1   19.17  ? 23  ASN A ND2 1 
ATOM   208  N  N   . LYS A 1 28  ? -17.561 -15.632 37.518  1   25.48  ? 24  LYS A N   1 
ATOM   209  C  CA  . LYS A 1 28  ? -17.845 -15.768 38.941  1   25.35  ? 24  LYS A CA  1 
ATOM   210  C  C   . LYS A 1 28  ? -19.33  -15.869 39.257  1   22.98  ? 24  LYS A C   1 
ATOM   211  O  O   . LYS A 1 28  ? -19.701 -16.381 40.31   1   21.42  ? 24  LYS A O   1 
ATOM   212  C  CB  . LYS A 1 28  ? -17.256 -14.597 39.717  1   28.76  ? 24  LYS A CB  1 
ATOM   213  C  CG  . LYS A 1 28  ? -15.729 -14.617 39.697  1   33.8   ? 24  LYS A CG  1 
ATOM   214  C  CD  . LYS A 1 28  ? -15.078 -13.607 40.668  1   37.95  ? 24  LYS A CD  1 
ATOM   215  C  CE  . LYS A 1 28  ? -15.089 -12.211 40.098  1   40.2   ? 24  LYS A CE  1 
ATOM   216  N  NZ  . LYS A 1 28  ? -14.149 -11.304 40.799  1   39.42  ? 24  LYS A NZ  1 
ATOM   217  N  N   . LEU A 1 29  ? -20.167 -15.359 38.349  1   22.96  ? 25  LEU A N   1 
ATOM   218  C  CA  . LEU A 1 29  ? -21.607 -15.339 38.555  1   22.07  ? 25  LEU A CA  1 
ATOM   219  C  C   . LEU A 1 29  ? -22.304 -16.576 37.987  1   22.64  ? 25  LEU A C   1 
ATOM   220  O  O   . LEU A 1 29  ? -23.183 -17.123 38.651  1   23.1   ? 25  LEU A O   1 
ATOM   221  C  CB  . LEU A 1 29  ? -22.182 -14.07  37.945  1   21.84  ? 25  LEU A CB  1 
ATOM   222  C  CG  . LEU A 1 29  ? -21.792 -12.786 38.68   1   21.32  ? 25  LEU A CG  1 
ATOM   223  C  CD1 . LEU A 1 29  ? -22.338 -11.559 37.955  1   19.99  ? 25  LEU A CD1 1 
ATOM   224  C  CD2 . LEU A 1 29  ? -22.271 -12.82  40.113  1   20.73  ? 25  LEU A CD2 1 
ATOM   225  N  N   . THR A 1 30  ? -21.897 -17.025 36.79   1   20.52  ? 26  THR A N   1 
ATOM   226  C  CA  . THR A 1 30  ? -22.533 -18.167 36.15   1   22.37  ? 26  THR A CA  1 
ATOM   227  C  C   . THR A 1 30  ? -21.789 -19.492 36.315  1   24.9   ? 26  THR A C   1 
ATOM   228  O  O   . THR A 1 30  ? -22.368 -20.545 36.057  1   25.73  ? 26  THR A O   1 
ATOM   229  C  CB  . THR A 1 30  ? -22.712 -17.938 34.626  1   19.74  ? 26  THR A CB  1 
ATOM   230  O  OG1 . THR A 1 30  ? -21.442 -17.948 34.007  1   17.83  ? 26  THR A OG1 1 
ATOM   231  C  CG2 . THR A 1 30  ? -23.422 -16.646 34.31   1   20     ? 26  THR A CG2 1 
ATOM   232  N  N   . GLY A 1 31  ? -20.503 -19.428 36.688  1   26.7   ? 27  GLY A N   1 
ATOM   233  C  CA  . GLY A 1 31  ? -19.662 -20.611 36.827  1   24.88  ? 27  GLY A CA  1 
ATOM   234  C  C   . GLY A 1 31  ? -18.975 -21.049 35.535  1   23.97  ? 27  GLY A C   1 
ATOM   235  O  O   . GLY A 1 31  ? -18.154 -21.96  35.549  1   24.72  ? 27  GLY A O   1 
ATOM   236  N  N   . GLU A 1 32  ? -19.286 -20.378 34.425  1   24.65  ? 28  GLU A N   1 
ATOM   237  C  CA  . GLU A 1 32  ? -18.767 -20.779 33.126  1   26.81  ? 28  GLU A CA  1 
ATOM   238  C  C   . GLU A 1 32  ? -17.251 -20.606 33.045  1   30.05  ? 28  GLU A C   1 
ATOM   239  O  O   . GLU A 1 32  ? -16.709 -19.562 33.398  1   31.16  ? 28  GLU A O   1 
ATOM   240  C  CB  . GLU A 1 32  ? -19.434 -19.959 32.01   1   26.72  ? 28  GLU A CB  1 
ATOM   241  C  CG  . GLU A 1 32  ? -19.11  -20.47  30.62   1   28.08  ? 28  GLU A CG  1 
ATOM   242  C  CD  . GLU A 1 32  ? -19.769 -19.73  29.48   1   27.8   ? 28  GLU A CD  1 
ATOM   243  O  OE1 . GLU A 1 32  ? -20.258 -18.594 29.673  1   25.83  ? 28  GLU A OE1 1 
ATOM   244  O  OE2 . GLU A 1 32  ? -19.797 -20.309 28.376  1   34.73  ? 28  GLU A OE2 1 
ATOM   245  N  N   . VAL A 1 33  ? -16.578 -21.653 32.561  1   31.57  ? 29  VAL A N   1 
ATOM   246  C  CA  . VAL A 1 33  ? -15.155 -21.612 32.279  1   28.14  ? 29  VAL A CA  1 
ATOM   247  C  C   . VAL A 1 33  ? -14.948 -21.141 30.845  1   25.66  ? 29  VAL A C   1 
ATOM   248  O  O   . VAL A 1 33  ? -15.612 -21.615 29.934  1   23.14  ? 29  VAL A O   1 
ATOM   249  C  CB  . VAL A 1 33  ? -14.535 -22.993 32.525  1   28.96  ? 29  VAL A CB  1 
ATOM   250  C  CG1 . VAL A 1 33  ? -13.052 -22.99  32.218  1   31.24  ? 29  VAL A CG1 1 
ATOM   251  C  CG2 . VAL A 1 33  ? -14.787 -23.453 33.955  1   27.74  ? 29  VAL A CG2 1 
ATOM   252  N  N   . VAL A 1 34  ? -14.01  -20.208 30.664  1   25.93  ? 30  VAL A N   1 
ATOM   253  C  CA  . VAL A 1 34  ? -13.8   -19.544 29.391  1   23.33  ? 30  VAL A CA  1 
ATOM   254  C  C   . VAL A 1 34  ? -12.306 -19.417 29.111  1   23.02  ? 30  VAL A C   1 
ATOM   255  O  O   . VAL A 1 34  ? -11.48  -19.598 29.998  1   24.38  ? 30  VAL A O   1 
ATOM   256  C  CB  . VAL A 1 34  ? -14.469 -18.138 29.362  1   23.69  ? 30  VAL A CB  1 
ATOM   257  C  CG1 . VAL A 1 34  ? -15.965 -18.219 29.629  1   24.08  ? 30  VAL A CG1 1 
ATOM   258  C  CG2 . VAL A 1 34  ? -13.806 -17.183 30.335  1   22.27  ? 30  VAL A CG2 1 
ATOM   259  N  N   . ALA A 1 35  ? -11.975 -19.112 27.857  1   24.6   ? 31  ALA A N   1 
ATOM   260  C  CA  . ALA A 1 35  ? -10.64  -18.674 27.501  1   25.25  ? 31  ALA A CA  1 
ATOM   261  C  C   . ALA A 1 35  ? -10.737 -17.2   27.123  1   25.02  ? 31  ALA A C   1 
ATOM   262  O  O   . ALA A 1 35  ? -11.582 -16.828 26.316  1   26.21  ? 31  ALA A O   1 
ATOM   263  C  CB  . ALA A 1 35  ? -10.083 -19.495 26.366  1   25.06  ? 31  ALA A CB  1 
ATOM   264  N  N   . LEU A 1 36  ? -9.872  -16.384 27.734  1   25.81  ? 32  LEU A N   1 
ATOM   265  C  CA  . LEU A 1 36  ? -9.785  -14.959 27.475  1   27.39  ? 32  LEU A CA  1 
ATOM   266  C  C   . LEU A 1 36  ? -8.56   -14.709 26.607  1   29.78  ? 32  LEU A C   1 
ATOM   267  O  O   . LEU A 1 36  ? -7.455  -15     27.037  1   37.74  ? 32  LEU A O   1 
ATOM   268  C  CB  . LEU A 1 36  ? -9.6    -14.184 28.767  1   27.54  ? 32  LEU A CB  1 
ATOM   269  C  CG  . LEU A 1 36  ? -10.639 -14.318 29.818  1   28.8   ? 32  LEU A CG  1 
ATOM   270  C  CD1 . LEU A 1 36  ? -10.203 -13.547 31.069  1   28.54  ? 32  LEU A CD1 1 
ATOM   271  C  CD2 . LEU A 1 36  ? -11.995 -13.823 29.307  1   30.9   ? 32  LEU A CD2 1 
ATOM   272  N  N   . LYS A 1 37  ? -8.762  -14.17  25.404  1   30.99  ? 33  LYS A N   1 
ATOM   273  C  CA  . LYS A 1 37  ? -7.671  -13.811 24.524  1   35.95  ? 33  LYS A CA  1 
ATOM   274  C  C   . LYS A 1 37  ? -7.509  -12.293 24.603  1   38.58  ? 33  LYS A C   1 
ATOM   275  O  O   . LYS A 1 37  ? -8.388  -11.548 24.184  1   42.12  ? 33  LYS A O   1 
ATOM   276  C  CB  . LYS A 1 37  ? -7.964  -14.312 23.106  1   41.14  ? 33  LYS A CB  1 
ATOM   277  C  CG  . LYS A 1 37  ? -6.753  -14.242 22.182  1   43.04  ? 33  LYS A CG  1 
ATOM   278  C  CD  . LYS A 1 37  ? -7.065  -14.405 20.69   1   46.93  ? 33  LYS A CD  1 
ATOM   279  C  CE  . LYS A 1 37  ? -7.224  -15.841 20.221  1   53.94  ? 33  LYS A CE  1 
ATOM   280  N  NZ  . LYS A 1 37  ? -7.044  -15.983 18.731  1   53.46  ? 33  LYS A NZ  1 
ATOM   281  N  N   . LYS A 1 38  ? -6.389  -11.849 25.189  1   40.33  ? 34  LYS A N   1 
ATOM   282  C  CA  . LYS A 1 38  ? -6.051  -10.441 25.259  1   42.1   ? 34  LYS A CA  1 
ATOM   283  C  C   . LYS A 1 38  ? -5.443  -9.978  23.94   1   47.69  ? 34  LYS A C   1 
ATOM   284  O  O   . LYS A 1 38  ? -4.559  -10.637 23.407  1   50.26  ? 34  LYS A O   1 
ATOM   285  C  CB  . LYS A 1 38  ? -5.071  -10.191 26.396  1   44.12  ? 34  LYS A CB  1 
ATOM   286  C  CG  . LYS A 1 38  ? -4.877  -8.717  26.718  1   46.42  ? 34  LYS A CG  1 
ATOM   287  C  CD  . LYS A 1 38  ? -3.736  -8.447  27.718  1   52.66  ? 34  LYS A CD  1 
ATOM   288  C  CE  . LYS A 1 38  ? -3.961  -9.046  29.092  1   55.88  ? 34  LYS A CE  1 
ATOM   289  N  NZ  . LYS A 1 38  ? -2.774  -8.882  29.966  1   55.01  ? 34  LYS A NZ  1 
ATOM   290  N  N   . ILE A 1 39  ? -5.939  -8.845  23.427  1   54.07  ? 35  ILE A N   1 
ATOM   291  C  CA  . ILE A 1 39  ? -5.353  -8.161  22.284  1   57.1   ? 35  ILE A CA  1 
ATOM   292  C  C   . ILE A 1 39  ? -4.961  -6.76   22.748  1   63.73  ? 35  ILE A C   1 
ATOM   293  O  O   . ILE A 1 39  ? -5.82   -5.946  23.079  1   65.44  ? 35  ILE A O   1 
ATOM   294  C  CB  . ILE A 1 39  ? -6.321  -8.094  21.078  1   54.98  ? 35  ILE A CB  1 
ATOM   295  C  CG1 . ILE A 1 39  ? -6.904  -9.483  20.692  1   55.78  ? 35  ILE A CG1 1 
ATOM   296  C  CG2 . ILE A 1 39  ? -5.66   -7.421  19.89   1   51.69  ? 35  ILE A CG2 1 
ATOM   297  C  CD1 . ILE A 1 39  ? -5.961  -10.421 20.024  1   58.02  ? 35  ILE A CD1 1 
ATOM   298  N  N   . ARG A 1 40  ? -3.656  -6.491  22.811  1   73.59  ? 36  ARG A N   1 
ATOM   299  C  CA  . ARG A 1 40  ? -3.2    -5.225  23.361  1   76.94  ? 36  ARG A CA  1 
ATOM   300  C  C   . ARG A 1 40  ? -3.239  -4.181  22.25   1   75.32  ? 36  ARG A C   1 
ATOM   301  O  O   . ARG A 1 40  ? -2.769  -4.432  21.143  1   61.77  ? 36  ARG A O   1 
ATOM   302  C  CB  . ARG A 1 40  ? -1.813  -5.339  23.994  1   82.25  ? 36  ARG A CB  1 
ATOM   303  C  CG  . ARG A 1 40  ? -1.539  -4.199  24.952  1   84.8   ? 36  ARG A CG  1 
ATOM   304  C  CD  . ARG A 1 40  ? -0.437  -4.544  25.932  1   87.3   ? 36  ARG A CD  1 
ATOM   305  N  NE  . ARG A 1 40  ? -0.931  -5.376  27.025  1   86.78  ? 36  ARG A NE  1 
ATOM   306  C  CZ  . ARG A 1 40  ? -1.108  -4.955  28.274  1   79.75  ? 36  ARG A CZ  1 
ATOM   307  N  NH1 . ARG A 1 40  ? -1.018  -3.674  28.592  1   74.91  ? 36  ARG A NH1 1 
ATOM   308  N  NH2 . ARG A 1 40  ? -1.401  -5.839  29.223  1   78.13  ? 36  ARG A NH2 1 
ATOM   309  N  N   . LEU A 1 41  ? -3.861  -3.034  22.525  1   73.88  ? 37  LEU A N   1 
ATOM   310  C  CA  . LEU A 1 41  ? -4.03   -2.021  21.454  1   72.63  ? 37  LEU A CA  1 
ATOM   311  C  C   . LEU A 1 41  ? -3.224  -0.767  21.808  1   82.28  ? 37  LEU A C   1 
ATOM   312  O  O   . LEU A 1 41  ? -2.853  -0.022  20.883  1   79.05  ? 37  LEU A O   1 
ATOM   313  C  CB  . LEU A 1 41  ? -5.51   -1.696  21.268  1   63.73  ? 37  LEU A CB  1 
ATOM   314  C  CG  . LEU A 1 41  ? -6.507  -2.825  21.534  1   56.95  ? 37  LEU A CG  1 
ATOM   315  C  CD1 . LEU A 1 41  ? -7.852  -2.208  21.863  1   55.86  ? 37  LEU A CD1 1 
ATOM   316  C  CD2 . LEU A 1 41  ? -6.613  -3.692  20.297  1   55.99  ? 37  LEU A CD2 1 
ATOM   317  N  N   . ASP A 1 42  ? -2.975  -0.543  23.099  1   88.55  ? 38  ASP A N   1 
ATOM   318  C  CA  . ASP A 1 42  ? -2.26   0.687   23.532  1   88.44  ? 38  ASP A CA  1 
ATOM   319  C  C   . ASP A 1 42  ? -0.843  0.631   22.958  1   88.69  ? 38  ASP A C   1 
ATOM   320  O  O   . ASP A 1 42  ? -0.303  1.701   22.611  1   75.51  ? 38  ASP A O   1 
ATOM   321  C  CB  . ASP A 1 42  ? -2.347  0.863   25.04   1   90.65  ? 38  ASP A CB  1 
ATOM   322  C  CG  . ASP A 1 42  ? -1.733  2.14    25.595  1   91.73  ? 38  ASP A CG  1 
ATOM   323  O  OD1 . ASP A 1 42  ? -1.228  2.944   24.784  1   93.02  ? 38  ASP A OD1 1 
ATOM   324  O  OD2 . ASP A 1 42  ? -1.766  2.32    26.831  1   90.13  ? 38  ASP A OD2 1 
ATOM   325  N  N   . THR A 1 43  ? -0.272  -0.571  22.856  1   94.62  ? 39  THR A N   1 
ATOM   326  C  CA  . THR A 1 43  ? 1.052   -0.715  22.227  1   97.01  ? 39  THR A CA  1 
ATOM   327  C  C   . THR A 1 43  ? 0.907   -0.446  20.753  1   101.97 ? 39  THR A C   1 
ATOM   328  O  O   . THR A 1 43  ? 1.846   0.133   20.173  1   104.75 ? 39  THR A O   1 
ATOM   329  C  CB  . THR A 1 43  ? 1.578   -2.126  22.456  1   94.87  ? 39  THR A CB  1 
ATOM   330  O  OG1 . THR A 1 43  ? 2.929   -2.099  22.006  1   91.99  ? 39  THR A OG1 1 
ATOM   331  C  CG2 . THR A 1 43  ? 0.813   -3.169  21.664  1   91.85  ? 39  THR A CG2 1 
ATOM   332  N  N   . GLU A 1 44  ? -0.228  -0.829  20.163  1   99.81  ? 40  GLU A N   1 
ATOM   333  C  CA  . GLU A 1 44  ? -0.405  -0.699  18.692  1   89.85  ? 40  GLU A CA  1 
ATOM   334  C  C   . GLU A 1 44  ? -0.522  0.776   18.287  1   76.74  ? 40  GLU A C   1 
ATOM   335  O  O   . GLU A 1 44  ? -1.276  1.512   18.949  1   74.69  ? 40  GLU A O   1 
ATOM   336  C  CB  . GLU A 1 44  ? -1.625  -1.521  18.285  1   88.85  ? 40  GLU A CB  1 
ATOM   337  C  CG  . GLU A 1 44  ? -1.872  -1.528  16.779  1   89.8   ? 40  GLU A CG  1 
ATOM   338  C  CD  . GLU A 1 44  ? -0.775  -2.209  15.98   1   92.74  ? 40  GLU A CD  1 
ATOM   339  O  OE1 . GLU A 1 44  ? 0.061   -2.896  16.6    1   94.24  ? 40  GLU A OE1 1 
ATOM   340  O  OE2 . GLU A 1 44  ? -0.756  -2.057  14.741  1   90.66  ? 40  GLU A OE2 1 
ATOM   341  N  N   . THR A 1 45  ? 0.189   1.176   17.229  1   62.97  ? 41  THR A N   1 
ATOM   342  C  CA  . THR A 1 45  ? 0.082   2.562   16.735  1   58.57  ? 41  THR A CA  1 
ATOM   343  C  C   . THR A 1 45  ? -0.77   2.565   15.491  1   51.65  ? 41  THR A C   1 
ATOM   344  O  O   . THR A 1 45  ? -1.035  3.651   14.958  1   52.64  ? 41  THR A O   1 
ATOM   345  C  CB  . THR A 1 45  ? 1.49    3.077   16.459  1   59.21  ? 41  THR A CB  1 
ATOM   346  O  OG1 . THR A 1 45  ? 1.357   4.494   16.455  1   59.85  ? 41  THR A OG1 1 
ATOM   347  C  CG2 . THR A 1 45  ? 2.047   2.584   15.136  1   57.82  ? 41  THR A CG2 1 
ATOM   348  N  N   . GLU A 1 46  ? -1.183  1.389   15.029  1   44.48  ? 42  GLU A N   1 
ATOM   349  C  CA  . GLU A 1 46  ? -2.047  1.284   13.867  1   39.46  ? 42  GLU A CA  1 
ATOM   350  C  C   . GLU A 1 46  ? -3.48   0.918   14.259  1   30.89  ? 42  GLU A C   1 
ATOM   351  O  O   . GLU A 1 46  ? -4.263  0.458   13.439  1   30.04  ? 42  GLU A O   1 
ATOM   352  C  CB  . GLU A 1 46  ? -1.441  0.26    12.883  1   42.76  ? 42  GLU A CB  1 
ATOM   353  C  CG  . GLU A 1 46  ? -0.136  0.742   12.221  1   45.94  ? 42  GLU A CG  1 
ATOM   354  C  CD  . GLU A 1 46  ? -0.204  2.007   11.364  1   45.19  ? 42  GLU A CD  1 
ATOM   355  O  OE1 . GLU A 1 46  ? -0.794  1.927   10.259  1   41.44  ? 42  GLU A OE1 1 
ATOM   356  O  OE2 . GLU A 1 46  ? 0.353   3.061   11.767  1   44.81  ? 42  GLU A OE2 1 
ATOM   357  N  N   . GLY A 1 47  ? -3.846  1.162   15.518  1   29.53  ? 43  GLY A N   1 
ATOM   358  C  CA  . GLY A 1 47  ? -5.206  0.95    15.98   1   27.15  ? 43  GLY A CA  1 
ATOM   359  C  C   . GLY A 1 47  ? -5.489  -0.535  16.15   1   24.72  ? 43  GLY A C   1 
ATOM   360  O  O   . GLY A 1 47  ? -4.586  -1.3    16.465  1   25.45  ? 43  GLY A O   1 
ATOM   361  N  N   . VAL A 1 48  ? -6.743  -0.933  15.937  1   23.34  ? 44  VAL A N   1 
ATOM   362  C  CA  . VAL A 1 48  ? -7.121  -2.321  16.119  1   24.41  ? 44  VAL A CA  1 
ATOM   363  C  C   . VAL A 1 48  ? -6.539  -3.13   14.965  1   25.77  ? 44  VAL A C   1 
ATOM   364  O  O   . VAL A 1 48  ? -6.752  -2.804  13.801  1   26.17  ? 44  VAL A O   1 
ATOM   365  C  CB  . VAL A 1 48  ? -8.646  -2.493  16.242  1   23.7   ? 44  VAL A CB  1 
ATOM   366  C  CG1 . VAL A 1 48  ? -9.022  -3.942  16.491  1   24.54  ? 44  VAL A CG1 1 
ATOM   367  C  CG2 . VAL A 1 48  ? -9.196  -1.609  17.343  1   23.47  ? 44  VAL A CG2 1 
ATOM   368  N  N   . PRO A 1 49  ? -5.777  -4.21   15.241  1   26.89  ? 45  PRO A N   1 
ATOM   369  C  CA  . PRO A 1 49  ? -5.148  -4.976  14.173  1   27.88  ? 45  PRO A CA  1 
ATOM   370  C  C   . PRO A 1 49  ? -6.164  -5.727  13.316  1   28.77  ? 45  PRO A C   1 
ATOM   371  O  O   . PRO A 1 49  ? -7.197  -6.184  13.802  1   26.08  ? 45  PRO A O   1 
ATOM   372  C  CB  . PRO A 1 49  ? -4.192  -5.908  14.93   1   29.16  ? 45  PRO A CB  1 
ATOM   373  C  CG  . PRO A 1 49  ? -4.729  -6.013  16.292  1   29.36  ? 45  PRO A CG  1 
ATOM   374  C  CD  . PRO A 1 49  ? -5.47   -4.733  16.579  1   28.83  ? 45  PRO A CD  1 
ATOM   375  N  N   . SER A 1 50  ? -5.842  -5.847  12.026  1   29.38  ? 46  SER A N   1 
ATOM   376  C  CA  . SER A 1 50  ? -6.742  -6.454  11.066  1   29.03  ? 46  SER A CA  1 
ATOM   377  C  C   . SER A 1 50  ? -7.018  -7.927  11.358  1   29.09  ? 46  SER A C   1 
ATOM   378  O  O   . SER A 1 50  ? -8.108  -8.414  11.049  1   29.62  ? 46  SER A O   1 
ATOM   379  C  CB  . SER A 1 50  ? -6.196  -6.291  9.653   1   30.69  ? 46  SER A CB  1 
ATOM   380  O  OG  . SER A 1 50  ? -4.887  -6.813  9.536   1   31.41  ? 46  SER A OG  1 
ATOM   381  N  N   . THR A 1 51  ? -6.039  -8.63   11.942  1   26.8   ? 47  THR A N   1 
ATOM   382  C  CA  . THR A 1 51  ? -6.267  -10.006 12.36   1   27.53  ? 47  THR A CA  1 
ATOM   383  C  C   . THR A 1 51  ? -7.444  -10.081 13.323  1   23.93  ? 47  THR A C   1 
ATOM   384  O  O   . THR A 1 51  ? -8.285  -10.955 13.189  1   21.79  ? 47  THR A O   1 
ATOM   385  C  CB  . THR A 1 51  ? -5.036  -10.683 12.981  1   30.67  ? 47  THR A CB  1 
ATOM   386  O  OG1 . THR A 1 51  ? -4.469  -9.838  13.973  1   31.19  ? 47  THR A OG1 1 
ATOM   387  C  CG2 . THR A 1 51  ? -3.968  -11.017 11.933  1   33.67  ? 47  THR A CG2 1 
ATOM   388  N  N   . ALA A 1 52  ? -7.507  -9.148  14.271  1   24.74  ? 48  ALA A N   1 
ATOM   389  C  CA  . ALA A 1 52  ? -8.57   -9.144  15.264  1   26.09  ? 48  ALA A CA  1 
ATOM   390  C  C   . ALA A 1 52  ? -9.911  -8.686  14.678  1   26.04  ? 48  ALA A C   1 
ATOM   391  O  O   . ALA A 1 52  ? -10.951 -9.219  15.046  1   27.93  ? 48  ALA A O   1 
ATOM   392  C  CB  . ALA A 1 52  ? -8.169  -8.286  16.466  1   23.41  ? 48  ALA A CB  1 
ATOM   393  N  N   . ILE A 1 53  ? -9.883  -7.713  13.76   1   24.32  ? 49  ILE A N   1 
ATOM   394  C  CA  . ILE A 1 53  ? -11.085 -7.279  13.061  1   24.99  ? 49  ILE A CA  1 
ATOM   395  C  C   . ILE A 1 53  ? -11.732 -8.406  12.26   1   23.93  ? 49  ILE A C   1 
ATOM   396  O  O   . ILE A 1 53  ? -12.951 -8.566  12.269  1   21.96  ? 49  ILE A O   1 
ATOM   397  C  CB  . ILE A 1 53  ? -10.777 -6.071  12.167  1   25.44  ? 49  ILE A CB  1 
ATOM   398  C  CG1 . ILE A 1 53  ? -10.551 -4.829  13.036  1   25.35  ? 49  ILE A CG1 1 
ATOM   399  C  CG2 . ILE A 1 53  ? -11.885 -5.84   11.138  1   27.15  ? 49  ILE A CG2 1 
ATOM   400  C  CD1 . ILE A 1 53  ? -9.891  -3.749  12.37   1   25.79  ? 49  ILE A CD1 1 
ATOM   401  N  N   . ARG A 1 54  ? -10.903 -9.183  11.566  1   24.36  ? 50  ARG A N   1 
ATOM   402  C  CA  . ARG A 1 54  ? -11.388 -10.355 10.861  1   25.56  ? 50  ARG A CA  1 
ATOM   403  C  C   . ARG A 1 54  ? -11.839 -11.462 11.812  1   26.59  ? 50  ARG A C   1 
ATOM   404  O  O   . ARG A 1 54  ? -12.91  -12.029 11.623  1   26.63  ? 50  ARG A O   1 
ATOM   405  C  CB  . ARG A 1 54  ? -10.315 -10.89  9.91    1   25.76  ? 50  ARG A CB  1 
ATOM   406  C  CG  . ARG A 1 54  ? -10.124 -10.007 8.687   1   26.03  ? 50  ARG A CG  1 
ATOM   407  C  CD  . ARG A 1 54  ? -9.082  -10.594 7.771   1   26.25  ? 50  ARG A CD  1 
ATOM   408  N  NE  . ARG A 1 54  ? -8.858  -9.771  6.594   1   25.07  ? 50  ARG A NE  1 
ATOM   409  C  CZ  . ARG A 1 54  ? -7.842  -9.941  5.759   1   25.87  ? 50  ARG A CZ  1 
ATOM   410  N  NH1 . ARG A 1 54  ? -6.963  -10.918 5.935   1   26.76  ? 50  ARG A NH1 1 
ATOM   411  N  NH2 . ARG A 1 54  ? -7.699  -9.109  4.728   1   22.62  ? 50  ARG A NH2 1 
ATOM   412  N  N   . GLU A 1 55  ? -11.026 -11.782 12.823  1   28.13  ? 51  GLU A N   1 
ATOM   413  C  CA  . GLU A 1 55  ? -11.378 -12.845 13.752  1   27.3   ? 51  GLU A CA  1 
ATOM   414  C  C   . GLU A 1 55  ? -12.727 -12.559 14.4    1   25.12  ? 51  GLU A C   1 
ATOM   415  O  O   . GLU A 1 55  ? -13.602 -13.41  14.371  1   23.91  ? 51  GLU A O   1 
ATOM   416  C  CB  . GLU A 1 55  ? -10.31  -13.085 14.838  1   28.51  ? 51  GLU A CB  1 
ATOM   417  C  CG  . GLU A 1 55  ? -10.745 -14.159 15.83   1   33.4   ? 51  GLU A CG  1 
ATOM   418  C  CD  . GLU A 1 55  ? -9.638  -14.916 16.546  1   36.85  ? 51  GLU A CD  1 
ATOM   419  O  OE1 . GLU A 1 55  ? -8.677  -14.236 16.951  1   32.33  ? 51  GLU A OE1 1 
ATOM   420  O  OE2 . GLU A 1 55  ? -9.746  -16.159 16.733  1   47.03  ? 51  GLU A OE2 1 
ATOM   421  N  N   . ILE A 1 56  ? -12.896 -11.363 14.965  1   24.31  ? 52  ILE A N   1 
ATOM   422  C  CA  . ILE A 1 56  ? -14.112 -11.035 15.688  1   25.6   ? 52  ILE A CA  1 
ATOM   423  C  C   . ILE A 1 56  ? -15.322 -11.007 14.756  1   27.19  ? 52  ILE A C   1 
ATOM   424  O  O   . ILE A 1 56  ? -16.324 -11.677 15.025  1   29.84  ? 52  ILE A O   1 
ATOM   425  C  CB  . ILE A 1 56  ? -13.978 -9.697  16.458  1   25.45  ? 52  ILE A CB  1 
ATOM   426  C  CG1 . ILE A 1 56  ? -12.846 -9.739  17.5    1   25.31  ? 52  ILE A CG1 1 
ATOM   427  C  CG2 . ILE A 1 56  ? -15.307 -9.336  17.106  1   24.8   ? 52  ILE A CG2 1 
ATOM   428  C  CD1 . ILE A 1 56  ? -12.369 -8.339  17.964  1   25.82  ? 52  ILE A CD1 1 
ATOM   429  N  N   . SER A 1 57  ? -15.222 -10.223 13.673  1   25.93  ? 53  SER A N   1 
ATOM   430  C  CA  . SER A 1 57  ? -16.323 -10.077 12.725  1   28.33  ? 53  SER A CA  1 
ATOM   431  C  C   . SER A 1 57  ? -16.777 -11.414 12.13   1   25.93  ? 53  SER A C   1 
ATOM   432  O  O   . SER A 1 57  ? -17.974 -11.671 12.024  1   28.93  ? 53  SER A O   1 
ATOM   433  C  CB  . SER A 1 57  ? -15.977 -9.095  11.602  1   26.65  ? 53  SER A CB  1 
ATOM   434  O  OG  . SER A 1 57  ? -14.924 -9.576  10.781  1   29.33  ? 53  SER A OG  1 
ATOM   435  N  N   . LEU A 1 58  ? -15.826 -12.28  11.777  1   24.57  ? 54  LEU A N   1 
ATOM   436  C  CA  . LEU A 1 58  ? -16.174 -13.56  11.178  1   26.32  ? 54  LEU A CA  1 
ATOM   437  C  C   . LEU A 1 58  ? -16.721 -14.548 12.203  1   29.81  ? 54  LEU A C   1 
ATOM   438  O  O   . LEU A 1 58  ? -17.707 -15.22  11.92   1   33.59  ? 54  LEU A O   1 
ATOM   439  C  CB  . LEU A 1 58  ? -14.992 -14.139 10.417  1   25.78  ? 54  LEU A CB  1 
ATOM   440  C  CG  . LEU A 1 58  ? -14.525 -13.231 9.281   1   26.39  ? 54  LEU A CG  1 
ATOM   441  C  CD1 . LEU A 1 58  ? -13.305 -13.831 8.532   1   27.95  ? 54  LEU A CD1 1 
ATOM   442  C  CD2 . LEU A 1 58  ? -15.673 -12.927 8.363   1   24.17  ? 54  LEU A CD2 1 
ATOM   443  N  N   . LEU A 1 59  ? -16.131 -14.597 13.407  1   33.58  ? 55  LEU A N   1 
ATOM   444  C  CA  . LEU A 1 59  ? -16.602 -15.514 14.438  1   32.51  ? 55  LEU A CA  1 
ATOM   445  C  C   . LEU A 1 59  ? -17.976 -15.163 15      1   33.3   ? 55  LEU A C   1 
ATOM   446  O  O   . LEU A 1 59  ? -18.67  -16.048 15.5    1   28.72  ? 55  LEU A O   1 
ATOM   447  C  CB  . LEU A 1 59  ? -15.615 -15.613 15.599  1   32.21  ? 55  LEU A CB  1 
ATOM   448  C  CG  . LEU A 1 59  ? -14.471 -16.607 15.362  1   35.66  ? 55  LEU A CG  1 
ATOM   449  C  CD1 . LEU A 1 59  ? -13.6   -16.709 16.536  1   36.04  ? 55  LEU A CD1 1 
ATOM   450  C  CD2 . LEU A 1 59  ? -14.981 -17.983 15.032  1   37.59  ? 55  LEU A CD2 1 
ATOM   451  N  N   . LYS A 1 60  ? -18.358 -13.883 14.923  1   37.36  ? 56  LYS A N   1 
ATOM   452  C  CA  . LYS A 1 60  ? -19.686 -13.465 15.343  1   41.16  ? 56  LYS A CA  1 
ATOM   453  C  C   . LYS A 1 60  ? -20.769 -14.127 14.494  1   40.02  ? 56  LYS A C   1 
ATOM   454  O  O   . LYS A 1 60  ? -21.827 -14.478 15.001  1   44.25  ? 56  LYS A O   1 
ATOM   455  C  CB  . LYS A 1 60  ? -19.826 -11.936 15.294  1   40.56  ? 56  LYS A CB  1 
ATOM   456  C  CG  . LYS A 1 60  ? -19.355 -11.278 16.584  1   44.65  ? 56  LYS A CG  1 
ATOM   457  C  CD  . LYS A 1 60  ? -19.462 -9.787  16.553  1   49.67  ? 56  LYS A CD  1 
ATOM   458  C  CE  . LYS A 1 60  ? -20.874 -9.27   16.465  1   52.92  ? 56  LYS A CE  1 
ATOM   459  N  NZ  . LYS A 1 60  ? -21.508 -9.209  17.785  1   59.14  ? 56  LYS A NZ  1 
ATOM   460  N  N   . GLU A 1 61  ? -20.478 -14.302 13.206  1   40.31  ? 57  GLU A N   1 
ATOM   461  C  CA  . GLU A 1 61  ? -21.381 -14.973 12.289  1   46.42  ? 57  GLU A CA  1 
ATOM   462  C  C   . GLU A 1 61  ? -21.386 -16.498 12.425  1   42.13  ? 57  GLU A C   1 
ATOM   463  O  O   . GLU A 1 61  ? -22.427 -17.13  12.28   1   47.55  ? 57  GLU A O   1 
ATOM   464  C  CB  . GLU A 1 61  ? -20.999 -14.566 10.854  1   51.7   ? 57  GLU A CB  1 
ATOM   465  C  CG  . GLU A 1 61  ? -21.302 -13.1   10.574  1   54.76  ? 57  GLU A CG  1 
ATOM   466  C  CD  . GLU A 1 61  ? -21.063 -12.644 9.147   1   58.46  ? 57  GLU A CD  1 
ATOM   467  O  OE1 . GLU A 1 61  ? -21.235 -13.476 8.228   1   54.06  ? 57  GLU A OE1 1 
ATOM   468  O  OE2 . GLU A 1 61  ? -20.774 -11.439 8.946   1   58.71  ? 57  GLU A OE2 1 
ATOM   469  N  N   . LEU A 1 62  ? -20.22  -17.083 12.697  1   35.02  ? 58  LEU A N   1 
ATOM   470  C  CA  . LEU A 1 62  ? -20.039 -18.519 12.596  1   36.26  ? 58  LEU A CA  1 
ATOM   471  C  C   . LEU A 1 62  ? -20.447 -19.217 13.888  1   38.53  ? 58  LEU A C   1 
ATOM   472  O  O   . LEU A 1 62  ? -19.627 -19.399 14.786  1   44.1   ? 58  LEU A O   1 
ATOM   473  C  CB  . LEU A 1 62  ? -18.572 -18.849 12.268  1   34.41  ? 58  LEU A CB  1 
ATOM   474  C  CG  . LEU A 1 62  ? -18.065 -18.303 10.961  1   37.94  ? 58  LEU A CG  1 
ATOM   475  C  CD1 . LEU A 1 62  ? -16.598 -18.547 10.815  1   40.04  ? 58  LEU A CD1 1 
ATOM   476  C  CD2 . LEU A 1 62  ? -18.81  -18.916 9.773   1   39.36  ? 58  LEU A CD2 1 
ATOM   477  N  N   . ASN A 1 63  ? -21.712 -19.634 13.953  1   35.28  ? 59  ASN A N   1 
ATOM   478  C  CA  . ASN A 1 63  ? -22.22  -20.325 15.119  1   38.44  ? 59  ASN A CA  1 
ATOM   479  C  C   . ASN A 1 63  ? -22.501 -21.79  14.779  1   33.23  ? 59  ASN A C   1 
ATOM   480  O  O   . ASN A 1 63  ? -23.465 -22.094 14.088  1   32.38  ? 59  ASN A O   1 
ATOM   481  C  CB  . ASN A 1 63  ? -23.448 -19.602 15.643  1   41.7   ? 59  ASN A CB  1 
ATOM   482  C  CG  . ASN A 1 63  ? -23.495 -19.68  17.125  1   57.95  ? 59  ASN A CG  1 
ATOM   483  O  OD1 . ASN A 1 63  ? -22.645 -19.093 17.827  1   74.43  ? 59  ASN A OD1 1 
ATOM   484  N  ND2 . ASN A 1 63  ? -24.464 -20.415 17.653  1   64.48  ? 59  ASN A ND2 1 
ATOM   485  N  N   . HIS A 1 64  ? -21.637 -22.688 15.264  1   27.69  ? 60  HIS A N   1 
ATOM   486  C  CA  . HIS A 1 64  ? -21.682 -24.089 14.888  1   27.85  ? 60  HIS A CA  1 
ATOM   487  C  C   . HIS A 1 64  ? -21.003 -24.934 15.961  1   27.5   ? 60  HIS A C   1 
ATOM   488  O  O   . HIS A 1 64  ? -20.019 -24.508 16.564  1   30.05  ? 60  HIS A O   1 
ATOM   489  C  CB  . HIS A 1 64  ? -21.017 -24.316 13.499  1   28.12  ? 60  HIS A CB  1 
ATOM   490  C  CG  . HIS A 1 64  ? -21.156 -25.716 12.979  1   28.31  ? 60  HIS A CG  1 
ATOM   491  N  ND1 . HIS A 1 64  ? -20.283 -26.721 13.351  1   28.55  ? 60  HIS A ND1 1 
ATOM   492  C  CD2 . HIS A 1 64  ? -22.062 -26.231 12.12   1   28.38  ? 60  HIS A CD2 1 
ATOM   493  C  CE1 . HIS A 1 64  ? -20.701 -27.818 12.729  1   27.72  ? 60  HIS A CE1 1 
ATOM   494  N  NE2 . HIS A 1 64  ? -21.767 -27.558 11.969  1   26.54  ? 60  HIS A NE2 1 
ATOM   495  N  N   . PRO A 1 65  ? -21.492 -26.162 16.242  1   30.18  ? 61  PRO A N   1 
ATOM   496  C  CA  . PRO A 1 65  ? -20.905 -26.975 17.31   1   29.74  ? 61  PRO A CA  1 
ATOM   497  C  C   . PRO A 1 65  ? -19.426 -27.318 17.136  1   27.38  ? 61  PRO A C   1 
ATOM   498  O  O   . PRO A 1 65  ? -18.775 -27.653 18.111  1   31.09  ? 61  PRO A O   1 
ATOM   499  C  CB  . PRO A 1 65  ? -21.771 -28.245 17.304  1   29.7   ? 61  PRO A CB  1 
ATOM   500  C  CG  . PRO A 1 65  ? -22.98  -27.915 16.498  1   29.71  ? 61  PRO A CG  1 
ATOM   501  C  CD  . PRO A 1 65  ? -22.645 -26.808 15.59   1   29.04  ? 61  PRO A CD  1 
ATOM   502  N  N   . ASN A 1 66  ? -18.915 -27.272 15.9    1   25.73  ? 62  ASN A N   1 
ATOM   503  C  CA  . ASN A 1 66  ? -17.524 -27.603 15.623  1   26.66  ? 62  ASN A CA  1 
ATOM   504  C  C   . ASN A 1 66  ? -16.695 -26.379 15.232  1   27.79  ? 62  ASN A C   1 
ATOM   505  O  O   . ASN A 1 66  ? -15.66  -26.489 14.581  1   26.45  ? 62  ASN A O   1 
ATOM   506  C  CB  . ASN A 1 66  ? -17.482 -28.672 14.532  1   27.27  ? 62  ASN A CB  1 
ATOM   507  C  CG  . ASN A 1 66  ? -18.216 -29.913 14.962  1   27.06  ? 62  ASN A CG  1 
ATOM   508  O  OD1 . ASN A 1 66  ? -19.235 -30.267 14.421  1   30.6   ? 62  ASN A OD1 1 
ATOM   509  N  ND2 . ASN A 1 66  ? -17.735 -30.596 15.979  1   26.37  ? 62  ASN A ND2 1 
ATOM   510  N  N   . ILE A 1 67  ? -17.177 -25.196 15.624  1   28.89  ? 63  ILE A N   1 
ATOM   511  C  CA  . ILE A 1 67  ? -16.397 -23.975 15.543  1   27.26  ? 63  ILE A CA  1 
ATOM   512  C  C   . ILE A 1 67  ? -16.358 -23.382 16.948  1   29.07  ? 63  ILE A C   1 
ATOM   513  O  O   . ILE A 1 67  ? -17.384 -23.275 17.61   1   34.55  ? 63  ILE A O   1 
ATOM   514  C  CB  . ILE A 1 67  ? -16.993 -23.006 14.506  1   25.48  ? 63  ILE A CB  1 
ATOM   515  C  CG1 . ILE A 1 67  ? -17.007 -23.614 13.093  1   24.9   ? 63  ILE A CG1 1 
ATOM   516  C  CG2 . ILE A 1 67  ? -16.272 -21.677 14.517  1   24.93  ? 63  ILE A CG2 1 
ATOM   517  C  CD1 . ILE A 1 67  ? -17.803 -22.739 12.036  1   23.87  ? 63  ILE A CD1 1 
ATOM   518  N  N   . VAL A 1 68  ? -15.16  -23.023 17.412  1   31.74  ? 64  VAL A N   1 
ATOM   519  C  CA  . VAL A 1 68  ? -14.995 -22.41  18.719  1   31.14  ? 64  VAL A CA  1 
ATOM   520  C  C   . VAL A 1 68  ? -15.903 -21.185 18.802  1   29.2   ? 64  VAL A C   1 
ATOM   521  O  O   . VAL A 1 68  ? -15.981 -20.384 17.873  1   30.7   ? 64  VAL A O   1 
ATOM   522  C  CB  . VAL A 1 68  ? -13.527 -22.042 18.999  1   33.87  ? 64  VAL A CB  1 
ATOM   523  C  CG1 . VAL A 1 68  ? -13.031 -20.933 18.041  1   34.55  ? 64  VAL A CG1 1 
ATOM   524  C  CG2 . VAL A 1 68  ? -13.346 -21.645 20.474  1   34.32  ? 64  VAL A CG2 1 
ATOM   525  N  N   . LYS A 1 69  ? -16.606 -21.067 19.923  1   28.54  ? 65  LYS A N   1 
ATOM   526  C  CA  . LYS A 1 69  ? -17.661 -20.085 20.063  1   29.74  ? 65  LYS A CA  1 
ATOM   527  C  C   . LYS A 1 69  ? -17.119 -18.828 20.734  1   29.09  ? 65  LYS A C   1 
ATOM   528  O  O   . LYS A 1 69  ? -16.552 -18.915 21.817  1   28.34  ? 65  LYS A O   1 
ATOM   529  C  CB  . LYS A 1 69  ? -18.824 -20.682 20.854  1   33.41  ? 65  LYS A CB  1 
ATOM   530  C  CG  . LYS A 1 69  ? -20.01  -19.727 20.963  1   38.23  ? 65  LYS A CG  1 
ATOM   531  C  CD  . LYS A 1 69  ? -21.288 -20.467 21.39   1   45.58  ? 65  LYS A CD  1 
ATOM   532  C  CE  . LYS A 1 69  ? -22.456 -19.521 21.648  1   47.03  ? 65  LYS A CE  1 
ATOM   533  N  NZ  . LYS A 1 69  ? -22.672 -18.625 20.482  1   47.7   ? 65  LYS A NZ  1 
ATOM   534  N  N   . LEU A 1 70  ? -17.266 -17.68  20.057  1   28.39  ? 66  LEU A N   1 
ATOM   535  C  CA  . LEU A 1 70  ? -16.963 -16.38  20.634  1   28.24  ? 66  LEU A CA  1 
ATOM   536  C  C   . LEU A 1 70  ? -18.157 -15.926 21.468  1   27.68  ? 66  LEU A C   1 
ATOM   537  O  O   . LEU A 1 70  ? -19.239 -15.748 20.931  1   26.82  ? 66  LEU A O   1 
ATOM   538  C  CB  . LEU A 1 70  ? -16.675 -15.355 19.518  1   29.12  ? 66  LEU A CB  1 
ATOM   539  C  CG  . LEU A 1 70  ? -16.218 -13.965 19.977  1   29.45  ? 66  LEU A CG  1 
ATOM   540  C  CD1 . LEU A 1 70  ? -14.978 -14.042 20.832  1   29.26  ? 66  LEU A CD1 1 
ATOM   541  C  CD2 . LEU A 1 70  ? -15.914 -13.07  18.816  1   29.32  ? 66  LEU A CD2 1 
ATOM   542  N  N   . LEU A 1 71  ? -17.962 -15.775 22.783  1   27.77  ? 67  LEU A N   1 
ATOM   543  C  CA  . LEU A 1 71  ? -19.055 -15.465 23.692  1   27.23  ? 67  LEU A CA  1 
ATOM   544  C  C   . LEU A 1 71  ? -19.267 -13.964 23.85   1   25.33  ? 67  LEU A C   1 
ATOM   545  O  O   . LEU A 1 71  ? -20.393 -13.503 24.031  1   22.79  ? 67  LEU A O   1 
ATOM   546  C  CB  . LEU A 1 71  ? -18.792 -16.101 25.068  1   29.05  ? 67  LEU A CB  1 
ATOM   547  C  CG  . LEU A 1 71  ? -18.584 -17.638 25.038  1   33.79  ? 67  LEU A CG  1 
ATOM   548  C  CD1 . LEU A 1 71  ? -18.2   -18.179 26.392  1   33.09  ? 67  LEU A CD1 1 
ATOM   549  C  CD2 . LEU A 1 71  ? -19.853 -18.369 24.498  1   34.53  ? 67  LEU A CD2 1 
ATOM   550  N  N   . ASP A 1 72  ? -18.177 -13.2   23.765  1   26.21  ? 68  ASP A N   1 
ATOM   551  C  CA  . ASP A 1 72  ? -18.231 -11.788 24.094  1   25.67  ? 68  ASP A CA  1 
ATOM   552  C  C   . ASP A 1 72  ? -16.943 -11.093 23.673  1   24.26  ? 68  ASP A C   1 
ATOM   553  O  O   . ASP A 1 72  ? -15.94  -11.745 23.386  1   20.84  ? 68  ASP A O   1 
ATOM   554  C  CB  . ASP A 1 72  ? -18.45  -11.597 25.619  1   26.87  ? 68  ASP A CB  1 
ATOM   555  C  CG  . ASP A 1 72  ? -19.154 -10.322 26.011  1   28.17  ? 68  ASP A CG  1 
ATOM   556  O  OD1 . ASP A 1 72  ? -19.408 -9.488  25.122  1   28.87  ? 68  ASP A OD1 1 
ATOM   557  O  OD2 . ASP A 1 72  ? -19.48  -10.174 27.202  1   33.91  ? 68  ASP A OD2 1 
ATOM   558  N  N   . VAL A 1 73  ? -17.017 -9.759  23.614  1   23.47  ? 69  VAL A N   1 
ATOM   559  C  CA  . VAL A 1 73  ? -15.888 -8.911  23.302  1   23.14  ? 69  VAL A CA  1 
ATOM   560  C  C   . VAL A 1 73  ? -15.917 -7.745  24.28   1   23.34  ? 69  VAL A C   1 
ATOM   561  O  O   . VAL A 1 73  ? -16.842 -6.942  24.255  1   20.92  ? 69  VAL A O   1 
ATOM   562  C  CB  . VAL A 1 73  ? -15.926 -8.426  21.85   1   23.46  ? 69  VAL A CB  1 
ATOM   563  C  CG1 . VAL A 1 73  ? -14.812 -7.411  21.575  1   23.11  ? 69  VAL A CG1 1 
ATOM   564  C  CG2 . VAL A 1 73  ? -15.847 -9.61   20.885  1   23.7   ? 69  VAL A CG2 1 
ATOM   565  N  N   . ILE A 1 74  ? -14.894 -7.659  25.129  1   26.32  ? 70  ILE A N   1 
ATOM   566  C  CA  . ILE A 1 74  ? -14.781 -6.521  26.085  1   30.38  ? 70  ILE A CA  1 
ATOM   567  C  C   . ILE A 1 74  ? -13.789 -5.521  25.483  1   33.91  ? 70  ILE A C   1 
ATOM   568  O  O   . ILE A 1 74  ? -12.618 -5.878  25.319  1   32.11  ? 70  ILE A O   1 
ATOM   569  C  CB  . ILE A 1 74  ? -14.422 -7.009  27.498  1   32.12  ? 70  ILE A CB  1 
ATOM   570  C  CG1 . ILE A 1 74  ? -15.604 -7.731  28.138  1   33.85  ? 70  ILE A CG1 1 
ATOM   571  C  CG2 . ILE A 1 74  ? -13.931 -5.857  28.373  1   31.42  ? 70  ILE A CG2 1 
ATOM   572  C  CD1 . ILE A 1 74  ? -15.269 -9.086  28.727  1   35.17  ? 70  ILE A CD1 1 
ATOM   573  N  N   . HIS A 1 75  ? -14.263 -4.322  25.157  1   43.34  ? 71  HIS A N   1 
ATOM   574  C  CA  . HIS A 1 75  ? -13.43  -3.334  24.424  1   54.4   ? 71  HIS A CA  1 
ATOM   575  C  C   . HIS A 1 75  ? -13.14  -2.117  25.291  1   58.21  ? 71  HIS A C   1 
ATOM   576  O  O   . HIS A 1 75  ? -13.964 -1.189  25.326  1   67.72  ? 71  HIS A O   1 
ATOM   577  C  CB  . HIS A 1 75  ? -14.169 -2.891  23.155  1   62.12  ? 71  HIS A CB  1 
ATOM   578  C  CG  . HIS A 1 75  ? -13.35  -2.177  22.135  1   74.04  ? 71  HIS A CG  1 
ATOM   579  N  ND1 . HIS A 1 75  ? -13.904 -1.739  20.953  1   79.65  ? 71  HIS A ND1 1 
ATOM   580  C  CD2 . HIS A 1 75  ? -12.062 -1.821  22.093  1   83.37  ? 71  HIS A CD2 1 
ATOM   581  C  CE1 . HIS A 1 75  ? -12.971 -1.141  20.228  1   83.68  ? 71  HIS A CE1 1 
ATOM   582  N  NE2 . HIS A 1 75  ? -11.845 -1.177  20.903  1   78.17  ? 71  HIS A NE2 1 
ATOM   583  N  N   . THR A 1 76  ? -11.991 -2.117  25.957  1   64.86  ? 72  THR A N   1 
ATOM   584  C  CA  . THR A 1 76  ? -11.59  -0.944  26.753  1   64.69  ? 72  THR A CA  1 
ATOM   585  C  C   . THR A 1 76  ? -10.899 0.035   25.832  1   63.03  ? 72  THR A C   1 
ATOM   586  O  O   . THR A 1 76  ? -10.706 -0.297  24.646  1   51.27  ? 72  THR A O   1 
ATOM   587  C  CB  . THR A 1 76  ? -10.695 -1.406  27.904  1   62.7   ? 72  THR A CB  1 
ATOM   588  O  OG1 . THR A 1 76  ? -9.349  -1.249  27.469  1   60.34  ? 72  THR A OG1 1 
ATOM   589  C  CG2 . THR A 1 76  ? -10.928 -2.859  28.276  1   57.56  ? 72  THR A CG2 1 
ATOM   590  N  N   . GLU A 1 77  ? -10.549 1.216   26.338  1   64.5   ? 73  GLU A N   1 
ATOM   591  C  CA  . GLU A 1 77  ? -9.785  2.142   25.519  1   65.6   ? 73  GLU A CA  1 
ATOM   592  C  C   . GLU A 1 77  ? -8.417  1.57    25.157  1   62.34  ? 73  GLU A C   1 
ATOM   593  O  O   . GLU A 1 77  ? -7.904  1.837   24.071  1   58     ? 73  GLU A O   1 
ATOM   594  C  CB  . GLU A 1 77  ? -9.612  3.473   26.246  1   66.8   ? 73  GLU A CB  1 
ATOM   595  C  CG  . GLU A 1 77  ? -10.869 4.303   26.274  1   67.3   ? 73  GLU A CG  1 
ATOM   596  C  CD  . GLU A 1 77  ? -10.77  5.437   27.264  1   73.4   ? 73  GLU A CD  1 
ATOM   597  O  OE1 . GLU A 1 77  ? -9.801  6.226   27.171  1   71.98  ? 73  GLU A OE1 1 
ATOM   598  O  OE2 . GLU A 1 77  ? -11.645 5.513   28.156  1   78.3   ? 73  GLU A OE2 1 
ATOM   599  N  N   . ASN A 1 78  ? -7.86   0.755   26.061  1   60.21  ? 74  ASN A N   1 
ATOM   600  C  CA  . ASN A 1 78  ? -6.496  0.265   25.936  1   58.59  ? 74  ASN A CA  1 
ATOM   601  C  C   . ASN A 1 78  ? -6.363  -1.223  25.608  1   48.24  ? 74  ASN A C   1 
ATOM   602  O  O   . ASN A 1 78  ? -5.298  -1.649  25.17   1   47.26  ? 74  ASN A O   1 
ATOM   603  C  CB  . ASN A 1 78  ? -5.762  0.587   27.234  1   64.61  ? 74  ASN A CB  1 
ATOM   604  C  CG  . ASN A 1 78  ? -6.65   0.345   28.433  1   68.42  ? 74  ASN A CG  1 
ATOM   605  O  OD1 . ASN A 1 78  ? -7.659  1.033   28.65   1   65.73  ? 74  ASN A OD1 1 
ATOM   606  N  ND2 . ASN A 1 78  ? -6.322  -0.661  29.216  1   72.6   ? 74  ASN A ND2 1 
ATOM   607  N  N   . LYS A 1 79  ? -7.431  -2.009  25.816  1   44.18  ? 75  LYS A N   1 
ATOM   608  C  CA  . LYS A 1 79  ? -7.375  -3.449  25.61   1   43.57  ? 75  LYS A CA  1 
ATOM   609  C  C   . LYS A 1 79  ? -8.629  -4.041  24.972  1   38.46  ? 75  LYS A C   1 
ATOM   610  O  O   . LYS A 1 79  ? -9.7    -3.442  24.977  1   31.56  ? 75  LYS A O   1 
ATOM   611  C  CB  . LYS A 1 79  ? -7.121  -4.16   26.936  1   47.9   ? 75  LYS A CB  1 
ATOM   612  C  CG  . LYS A 1 79  ? -5.65   -4.121  27.342  1   55.84  ? 75  LYS A CG  1 
ATOM   613  C  CD  . LYS A 1 79  ? -5.361  -4.807  28.654  1   61.34  ? 75  LYS A CD  1 
ATOM   614  C  CE  . LYS A 1 79  ? -5.906  -4.058  29.852  1   61.81  ? 75  LYS A CE  1 
ATOM   615  N  NZ  . LYS A 1 79  ? -5.685  -4.817  31.106  1   64.01  ? 75  LYS A NZ  1 
ATOM   616  N  N   . LEU A 1 80  ? -8.465  -5.24   24.425  1   35.69  ? 76  LEU A N   1 
ATOM   617  C  CA  . LEU A 1 80  ? -9.555  -5.951  23.796  1   36.26  ? 76  LEU A CA  1 
ATOM   618  C  C   . LEU A 1 80  ? -9.457  -7.374  24.331  1   35.26  ? 76  LEU A C   1 
ATOM   619  O  O   . LEU A 1 80  ? -8.409  -7.999  24.206  1   34.41  ? 76  LEU A O   1 
ATOM   620  C  CB  . LEU A 1 80  ? -9.35   -5.864  22.283  1   40.66  ? 76  LEU A CB  1 
ATOM   621  C  CG  . LEU A 1 80  ? -10.312 -6.583  21.382  1   43.85  ? 76  LEU A CG  1 
ATOM   622  C  CD1 . LEU A 1 80  ? -11.701 -6.015  21.544  1   45.03  ? 76  LEU A CD1 1 
ATOM   623  C  CD2 . LEU A 1 80  ? -9.92   -6.466  19.976  1   48.92  ? 76  LEU A CD2 1 
ATOM   624  N  N   . TYR A 1 81  ? -10.534 -7.864  24.951  1   34.21  ? 77  TYR A N   1 
ATOM   625  C  CA  . TYR A 1 81  ? -10.611 -9.239  25.415  1   33.01  ? 77  TYR A CA  1 
ATOM   626  C  C   . TYR A 1 81  ? -11.653 -9.994  24.604  1   30.65  ? 77  TYR A C   1 
ATOM   627  O  O   . TYR A 1 81  ? -12.811 -9.588  24.552  1   29.16  ? 77  TYR A O   1 
ATOM   628  C  CB  . TYR A 1 81  ? -10.984 -9.297  26.899  1   35.33  ? 77  TYR A CB  1 
ATOM   629  C  CG  . TYR A 1 81  ? -9.86   -8.921  27.835  1   40.81  ? 77  TYR A CG  1 
ATOM   630  C  CD1 . TYR A 1 81  ? -8.852  -9.826  28.145  1   46.78  ? 77  TYR A CD1 1 
ATOM   631  C  CD2 . TYR A 1 81  ? -9.789  -7.655  28.393  1   41.5   ? 77  TYR A CD2 1 
ATOM   632  C  CE1 . TYR A 1 81  ? -7.816  -9.485  29.01   1   46.81  ? 77  TYR A CE1 1 
ATOM   633  C  CE2 . TYR A 1 81  ? -8.754  -7.301  29.25   1   44.17  ? 77  TYR A CE2 1 
ATOM   634  C  CZ  . TYR A 1 81  ? -7.77   -8.221  29.559  1   45.89  ? 77  TYR A CZ  1 
ATOM   635  O  OH  . TYR A 1 81  ? -6.747  -7.882  30.413  1   52.61  ? 77  TYR A OH  1 
ATOM   636  N  N   . LEU A 1 82  ? -11.224 -11.087 23.975  1   28.73  ? 78  LEU A N   1 
ATOM   637  C  CA  . LEU A 1 82  ? -12.139 -12.005 23.321  1   29.63  ? 78  LEU A CA  1 
ATOM   638  C  C   . LEU A 1 82  ? -12.457 -13.134 24.299  1   30.02  ? 78  LEU A C   1 
ATOM   639  O  O   . LEU A 1 82  ? -11.55  -13.818 24.763  1   28.33  ? 78  LEU A O   1 
ATOM   640  C  CB  . LEU A 1 82  ? -11.511 -12.555 22.036  1   30.45  ? 78  LEU A CB  1 
ATOM   641  C  CG  . LEU A 1 82  ? -11.515 -11.604 20.847  1   30.15  ? 78  LEU A CG  1 
ATOM   642  C  CD1 . LEU A 1 82  ? -10.653 -10.38  21.092  1   30.45  ? 78  LEU A CD1 1 
ATOM   643  C  CD2 . LEU A 1 82  ? -11.076 -12.311 19.615  1   29.27  ? 78  LEU A CD2 1 
ATOM   644  N  N   . VAL A 1 83  ? -13.743 -13.302 24.635  1   28.43  ? 79  VAL A N   1 
ATOM   645  C  CA  . VAL A 1 83  ? -14.177 -14.362 25.532  1   27.91  ? 79  VAL A CA  1 
ATOM   646  C  C   . VAL A 1 83  ? -14.682 -15.54  24.704  1   26.36  ? 79  VAL A C   1 
ATOM   647  O  O   . VAL A 1 83  ? -15.65  -15.394 23.961  1   25.92  ? 79  VAL A O   1 
ATOM   648  C  CB  . VAL A 1 83  ? -15.249 -13.859 26.512  1   26.71  ? 79  VAL A CB  1 
ATOM   649  C  CG1 . VAL A 1 83  ? -15.554 -14.906 27.568  1   26.41  ? 79  VAL A CG1 1 
ATOM   650  C  CG2 . VAL A 1 83  ? -14.825 -12.546 27.146  1   26.19  ? 79  VAL A CG2 1 
ATOM   651  N  N   . PHE A 1 84  ? -14.007 -16.69  24.85   1   26.38  ? 80  PHE A N   1 
ATOM   652  C  CA  . PHE A 1 84  ? -14.317 -17.912 24.125  1   26.25  ? 80  PHE A CA  1 
ATOM   653  C  C   . PHE A 1 84  ? -14.769 -19.028 25.057  1   27.16  ? 80  PHE A C   1 
ATOM   654  O  O   . PHE A 1 84  ? -14.382 -19.056 26.221  1   29.05  ? 80  PHE A O   1 
ATOM   655  C  CB  . PHE A 1 84  ? -13.076 -18.442 23.41   1   28.23  ? 80  PHE A CB  1 
ATOM   656  C  CG  . PHE A 1 84  ? -12.588 -17.659 22.227  1   29.41  ? 80  PHE A CG  1 
ATOM   657  C  CD1 . PHE A 1 84  ? -13.151 -17.836 20.979  1   31.69  ? 80  PHE A CD1 1 
ATOM   658  C  CD2 . PHE A 1 84  ? -11.557 -16.752 22.359  1   30.1   ? 80  PHE A CD2 1 
ATOM   659  C  CE1 . PHE A 1 84  ? -12.667 -17.129 19.874  1   32.3   ? 80  PHE A CE1 1 
ATOM   660  C  CE2 . PHE A 1 84  ? -11.086 -16.042 21.259  1   31.57  ? 80  PHE A CE2 1 
ATOM   661  C  CZ  . PHE A 1 84  ? -11.642 -16.239 20.021  1   29.73  ? 80  PHE A CZ  1 
ATOM   662  N  N   . GLU A 1 85  ? -15.53  -19.987 24.519  1   27.29  ? 81  GLU A N   1 
ATOM   663  C  CA  . GLU A 1 85  ? -15.792 -21.216 25.247  1   27.85  ? 81  GLU A CA  1 
ATOM   664  C  C   . GLU A 1 85  ? -14.439 -21.886 25.473  1   28.54  ? 81  GLU A C   1 
ATOM   665  O  O   . GLU A 1 85  ? -13.579 -21.823 24.602  1   28.41  ? 81  GLU A O   1 
ATOM   666  C  CB  . GLU A 1 85  ? -16.763 -22.137 24.499  1   29.43  ? 81  GLU A CB  1 
ATOM   667  C  CG  . GLU A 1 85  ? -16.186 -22.74  23.237  1   33.66  ? 81  GLU A CG  1 
ATOM   668  C  CD  . GLU A 1 85  ? -17.035 -23.818 22.599  1   32.35  ? 81  GLU A CD  1 
ATOM   669  O  OE1 . GLU A 1 85  ? -17.344 -24.829 23.278  1   31.81  ? 81  GLU A OE1 1 
ATOM   670  O  OE2 . GLU A 1 85  ? -17.352 -23.661 21.399  1   35.78  ? 81  GLU A OE2 1 
ATOM   671  N  N   . PHE A 1 86  ? -14.246 -22.479 26.657  1   26.96  ? 82  PHE A N   1 
ATOM   672  C  CA  . PHE A 1 86  ? -13.005 -23.161 26.977  1   26.6   ? 82  PHE A CA  1 
ATOM   673  C  C   . PHE A 1 86  ? -12.995 -24.607 26.487  1   25.73  ? 82  PHE A C   1 
ATOM   674  O  O   . PHE A 1 86  ? -13.964 -25.32  26.671  1   27.35  ? 82  PHE A O   1 
ATOM   675  C  CB  . PHE A 1 86  ? -12.799 -23.162 28.478  1   27.22  ? 82  PHE A CB  1 
ATOM   676  C  CG  . PHE A 1 86  ? -11.568 -23.93  28.91   1   26.78  ? 82  PHE A CG  1 
ATOM   677  C  CD1 . PHE A 1 86  ? -10.294 -23.423 28.675  1   24.47  ? 82  PHE A CD1 1 
ATOM   678  C  CD2 . PHE A 1 86  ? -11.687 -25.159 29.544  1   25.57  ? 82  PHE A CD2 1 
ATOM   679  C  CE1 . PHE A 1 86  ? -9.166  -24.127 29.069  1   23.39  ? 82  PHE A CE1 1 
ATOM   680  C  CE2 . PHE A 1 86  ? -10.557 -25.858 29.944  1   25.08  ? 82  PHE A CE2 1 
ATOM   681  C  CZ  . PHE A 1 86  ? -9.302  -25.336 29.706  1   24.17  ? 82  PHE A CZ  1 
ATOM   682  N  N   . LEU A 1 87  ? -11.884 -25.036 25.89   1   28.92  ? 83  LEU A N   1 
ATOM   683  C  CA  . LEU A 1 87  ? -11.661 -26.431 25.54   1   30.44  ? 83  LEU A CA  1 
ATOM   684  C  C   . LEU A 1 87  ? -10.289 -26.814 26.088  1   28.6   ? 83  LEU A C   1 
ATOM   685  O  O   . LEU A 1 87  ? -9.346  -26.027 26.01   1   30.48  ? 83  LEU A O   1 
ATOM   686  C  CB  . LEU A 1 87  ? -11.759 -26.629 24.044  1   31.18  ? 83  LEU A CB  1 
ATOM   687  C  CG  . LEU A 1 87  ? -13.18  -26.464 23.493  1   34.37  ? 83  LEU A CG  1 
ATOM   688  C  CD1 . LEU A 1 87  ? -13.347 -25.117 22.811  1   35.29  ? 83  LEU A CD1 1 
ATOM   689  C  CD2 . LEU A 1 87  ? -13.524 -27.589 22.559  1   34.94  ? 83  LEU A CD2 1 
ATOM   690  N  N   A HIS A 1 88  ? -10.174 -28.022 26.655  0.5 28.48  ? 84  HIS A N   1 
ATOM   691  N  N   B HIS A 1 88  ? -10.199 -28.032 26.62   0.5 28.78  ? 84  HIS A N   1 
ATOM   692  C  CA  A HIS A 1 88  ? -9.047  -28.306 27.534  0.5 27.92  ? 84  HIS A CA  1 
ATOM   693  C  CA  B HIS A 1 88  ? -9.126  -28.42  27.518  0.5 28.35  ? 84  HIS A CA  1 
ATOM   694  C  C   A HIS A 1 88  ? -7.725  -28.425 26.781  0.5 28.92  ? 84  HIS A C   1 
ATOM   695  C  C   B HIS A 1 88  ? -7.779  -28.692 26.846  0.5 30.31  ? 84  HIS A C   1 
ATOM   696  O  O   A HIS A 1 88  ? -6.687  -28.044 27.309  0.5 28.09  ? 84  HIS A O   1 
ATOM   697  O  O   B HIS A 1 88  ? -6.751  -28.74  27.519  0.5 32.23  ? 84  HIS A O   1 
ATOM   698  C  CB  A HIS A 1 88  ? -9.317  -29.492 28.521  0.5 26.79  ? 84  HIS A CB  1 
ATOM   699  C  CB  B HIS A 1 88  ? -9.653  -29.608 28.345  0.5 26.85  ? 84  HIS A CB  1 
ATOM   700  C  CG  A HIS A 1 88  ? -9.169  -30.906 28.028  0.5 24.93  ? 84  HIS A CG  1 
ATOM   701  C  CG  B HIS A 1 88  ? -11.105 -29.456 28.711  0.5 23.81  ? 84  HIS A CG  1 
ATOM   702  N  ND1 A HIS A 1 88  ? -8.232  -31.756 28.576  0.5 23.72  ? 84  HIS A ND1 1 
ATOM   703  N  ND1 B HIS A 1 88  ? -12.072 -29.186 27.744  0.5 20     ? 84  HIS A ND1 1 
ATOM   704  C  CD2 A HIS A 1 88  ? -9.885  -31.596 27.115  0.5 24.64  ? 84  HIS A CD2 1 
ATOM   705  C  CD2 B HIS A 1 88  ? -11.71  -29.519 29.919  0.5 22.39  ? 84  HIS A CD2 1 
ATOM   706  C  CE1 A HIS A 1 88  ? -8.376  -32.919 27.961  0.5 23.99  ? 84  HIS A CE1 1 
ATOM   707  C  CE1 B HIS A 1 88  ? -13.221 -29.104 28.385  0.5 20.5   ? 84  HIS A CE1 1 
ATOM   708  N  NE2 A HIS A 1 88  ? -9.364  -32.87  27.073  0.5 24.03  ? 84  HIS A NE2 1 
ATOM   709  N  NE2 B HIS A 1 88  ? -13.053 -29.302 29.7    0.5 22.26  ? 84  HIS A NE2 1 
ATOM   710  N  N   . GLN A 1 89  ? -7.767  -28.86  25.521  1   31.15  ? 85  GLN A N   1 
ATOM   711  C  CA  . GLN A 1 89  ? -6.548  -29.238 24.816  1   33.2   ? 85  GLN A CA  1 
ATOM   712  C  C   . GLN A 1 89  ? -6.647  -29.051 23.307  1   30.31  ? 85  GLN A C   1 
ATOM   713  O  O   . GLN A 1 89  ? -7.754  -28.962 22.796  1   28.68  ? 85  GLN A O   1 
ATOM   714  C  CB  . GLN A 1 89  ? -6.289  -30.715 25.104  1   36.83  ? 85  GLN A CB  1 
ATOM   715  C  CG  . GLN A 1 89  ? -4.915  -31.204 24.73   1   41.31  ? 85  GLN A CG  1 
ATOM   716  C  CD  . GLN A 1 89  ? -4.777  -32.652 25.107  1   48.32  ? 85  GLN A CD  1 
ATOM   717  O  OE1 . GLN A 1 89  ? -5.68   -33.447 24.854  1   63.23  ? 85  GLN A OE1 1 
ATOM   718  N  NE2 . GLN A 1 89  ? -3.681  -33.02  25.729  1   53.48  ? 85  GLN A NE2 1 
ATOM   719  N  N   . ASP A 1 90  ? -5.507  -29.007 22.609  1   29.13  ? 86  ASP A N   1 
ATOM   720  C  CA  . ASP A 1 90  ? -5.494  -29.044 21.155  1   32.85  ? 86  ASP A CA  1 
ATOM   721  C  C   . ASP A 1 90  ? -5.057  -30.418 20.638  1   33.9   ? 86  ASP A C   1 
ATOM   722  O  O   . ASP A 1 90  ? -4.478  -31.219 21.378  1   32.58  ? 86  ASP A O   1 
ATOM   723  C  CB  . ASP A 1 90  ? -4.6    -27.922 20.593  1   34.4   ? 86  ASP A CB  1 
ATOM   724  C  CG  . ASP A 1 90  ? -3.136  -28.102 20.82   1   36.23  ? 86  ASP A CG  1 
ATOM   725  O  OD1 . ASP A 1 90  ? -2.574  -29.029 20.261  1   37.18  ? 86  ASP A OD1 1 
ATOM   726  O  OD2 . ASP A 1 90  ? -2.552  -27.299 21.546  1   46.06  ? 86  ASP A OD2 1 
ATOM   727  N  N   . LEU A 1 91  ? -5.314  -30.667 19.345  1   32.52  ? 87  LEU A N   1 
ATOM   728  C  CA  . LEU A 1 91  ? -5.122  -31.979 18.748  1   31.78  ? 87  LEU A CA  1 
ATOM   729  C  C   . LEU A 1 91  ? -3.643  -32.374 18.697  1   31.17  ? 87  LEU A C   1 
ATOM   730  O  O   . LEU A 1 91  ? -3.305  -33.555 18.798  1   34.71  ? 87  LEU A O   1 
ATOM   731  C  CB  . LEU A 1 91  ? -5.752  -32.001 17.345  1   31.8   ? 87  LEU A CB  1 
ATOM   732  C  CG  . LEU A 1 91  ? -5.586  -33.286 16.542  1   31.95  ? 87  LEU A CG  1 
ATOM   733  C  CD1 . LEU A 1 91  ? -6.328  -34.437 17.201  1   31.66  ? 87  LEU A CD1 1 
ATOM   734  C  CD2 . LEU A 1 91  ? -6.049  -33.09  15.108  1   32.84  ? 87  LEU A CD2 1 
ATOM   735  N  N   . LYS A 1 92  ? -2.764  -31.379 18.559  1   31.94  ? 88  LYS A N   1 
ATOM   736  C  CA  . LYS A 1 92  ? -1.333  -31.631 18.531  1   35.84  ? 88  LYS A CA  1 
ATOM   737  C  C   . LYS A 1 92  ? -0.847  -32.208 19.862  1   35.37  ? 88  LYS A C   1 
ATOM   738  O  O   . LYS A 1 92  ? -0.125  -33.205 19.88   1   38.6   ? 88  LYS A O   1 
ATOM   739  C  CB  . LYS A 1 92  ? -0.558  -30.351 18.183  1   38.57  ? 88  LYS A CB  1 
ATOM   740  C  CG  . LYS A 1 92  ? 0.963   -30.522 18.184  1   39.85  ? 88  LYS A CG  1 
ATOM   741  C  CD  . LYS A 1 92  ? 1.406   -31.619 17.209  1   50.94  ? 88  LYS A CD  1 
ATOM   742  C  CE  . LYS A 1 92  ? 2.883   -31.848 17.216  1   55.8   ? 88  LYS A CE  1 
ATOM   743  N  NZ  . LYS A 1 92  ? 3.224   -33.098 16.513  1   60.08  ? 88  LYS A NZ  1 
ATOM   744  N  N   . LYS A 1 93  ? -1.25   -31.584 20.974  1   34.44  ? 89  LYS A N   1 
ATOM   745  C  CA  . LYS A 1 93  ? -0.867  -32.053 22.298  1   38.79  ? 89  LYS A CA  1 
ATOM   746  C  C   . LYS A 1 93  ? -1.429  -33.442 22.576  1   37.3   ? 89  LYS A C   1 
ATOM   747  O  O   . LYS A 1 93  ? -0.734  -34.282 23.149  1   34.74  ? 89  LYS A O   1 
ATOM   748  C  CB  . LYS A 1 93  ? -1.309  -31.07  23.383  1   42.24  ? 89  LYS A CB  1 
ATOM   749  C  CG  . LYS A 1 93  ? -0.462  -29.802 23.36   1   54.18  ? 89  LYS A CG  1 
ATOM   750  C  CD  . LYS A 1 93  ? -0.826  -28.78  24.435  1   66.89  ? 89  LYS A CD  1 
ATOM   751  C  CE  . LYS A 1 93  ? -0.293  -27.408 24.08   1   70.04  ? 89  LYS A CE  1 
ATOM   752  N  NZ  . LYS A 1 93  ? -0.844  -26.362 24.975  1   77.04  ? 89  LYS A NZ  1 
ATOM   753  N  N   . PHE A 1 94  ? -2.674  -33.669 22.135  1   34.84  ? 90  PHE A N   1 
ATOM   754  C  CA  . PHE A 1 94  ? -3.318  -34.965 22.268  1   35.93  ? 90  PHE A CA  1 
ATOM   755  C  C   . PHE A 1 94  ? -2.535  -36.04  21.519  1   32.5   ? 90  PHE A C   1 
ATOM   756  O  O   . PHE A 1 94  ? -2.238  -37.097 22.068  1   33.73  ? 90  PHE A O   1 
ATOM   757  C  CB  . PHE A 1 94  ? -4.768  -34.91  21.751  1   37.04  ? 90  PHE A CB  1 
ATOM   758  C  CG  . PHE A 1 94  ? -5.498  -36.223 21.861  1   35.05  ? 90  PHE A CG  1 
ATOM   759  C  CD1 . PHE A 1 94  ? -5.727  -36.802 23.093  1   36.7   ? 90  PHE A CD1 1 
ATOM   760  C  CD2 . PHE A 1 94  ? -5.932  -36.893 20.729  1   37.94  ? 90  PHE A CD2 1 
ATOM   761  C  CE1 . PHE A 1 94  ? -6.401  -38.023 23.196  1   38.12  ? 90  PHE A CE1 1 
ATOM   762  C  CE2 . PHE A 1 94  ? -6.608  -38.113 20.832  1   39.56  ? 90  PHE A CE2 1 
ATOM   763  C  CZ  . PHE A 1 94  ? -6.833  -38.671 22.062  1   41.63  ? 90  PHE A CZ  1 
ATOM   764  N  N   . MET A 1 95  ? -2.19   -35.753 20.262  1   33.98  ? 91  MET A N   1 
ATOM   765  C  CA  . MET A 1 95  ? -1.388  -36.669 19.465  1   36.7   ? 91  MET A CA  1 
ATOM   766  C  C   . MET A 1 95  ? -0.051  -36.989 20.136  1   37.76  ? 91  MET A C   1 
ATOM   767  O  O   . MET A 1 95  ? 0.315   -38.154 20.246  1   42.11  ? 91  MET A O   1 
ATOM   768  C  CB  . MET A 1 95  ? -1.174  -36.082 18.069  1   37.48  ? 91  MET A CB  1 
ATOM   769  C  CG  . MET A 1 95  ? -2.313  -36.38  17.149  1   39.09  ? 91  MET A CG  1 
ATOM   770  S  SD  . MET A 1 95  ? -2.101  -35.76  15.464  1   46.32  ? 91  MET A SD  1 
ATOM   771  C  CE  . MET A 1 95  ? -1.572  -34.094 15.721  1   39.49  ? 91  MET A CE  1 
ATOM   772  N  N   . ASP A 1 96  ? 0.663   -35.953 20.598  1   37.67  ? 92  ASP A N   1 
ATOM   773  C  CA  . ASP A 1 96  ? 1.929   -36.141 21.288  1   38.19  ? 92  ASP A CA  1 
ATOM   774  C  C   . ASP A 1 96  ? 1.806   -36.937 22.583  1   39.9   ? 92  ASP A C   1 
ATOM   775  O  O   . ASP A 1 96  ? 2.627   -37.815 22.83   1   39.48  ? 92  ASP A O   1 
ATOM   776  C  CB  . ASP A 1 96  ? 2.578   -34.783 21.629  1   36.56  ? 92  ASP A CB  1 
ATOM   777  C  CG  . ASP A 1 96  ? 3.092   -34.029 20.43   1   36.46  ? 92  ASP A CG  1 
ATOM   778  O  OD1 . ASP A 1 96  ? 3.213   -34.643 19.348  1   34.59  ? 92  ASP A OD1 1 
ATOM   779  O  OD2 . ASP A 1 96  ? 3.358   -32.815 20.564  1   39.67  ? 92  ASP A OD2 1 
ATOM   780  N  N   . ALA A 1 97  ? 0.81    -36.603 23.419  1   44.99  ? 93  ALA A N   1 
ATOM   781  C  CA  . ALA A 1 97  ? 0.91    -36.924 24.845  1   54.63  ? 93  ALA A CA  1 
ATOM   782  C  C   . ALA A 1 97  ? 0.211   -38.237 25.192  1   55.97  ? 93  ALA A C   1 
ATOM   783  O  O   . ALA A 1 97  ? 0.811   -39.117 25.805  1   64.79  ? 93  ALA A O   1 
ATOM   784  C  CB  . ALA A 1 97  ? 0.373   -35.784 25.719  1   55.36  ? 93  ALA A CB  1 
ATOM   785  N  N   . SER A 1 98  ? -1.07   -38.339 24.833  1   58.52  ? 94  SER A N   1 
ATOM   786  C  CA  . SER A 1 98  ? -1.723  -39.628 24.698  1   58.61  ? 94  SER A CA  1 
ATOM   787  C  C   . SER A 1 98  ? -1.387  -40.014 23.264  1   57.63  ? 94  SER A C   1 
ATOM   788  O  O   . SER A 1 98  ? -0.552  -39.367 22.635  1   53.7   ? 94  SER A O   1 
ATOM   789  C  CB  . SER A 1 98  ? -3.229  -39.543 24.953  1   56.45  ? 94  SER A CB  1 
ATOM   790  O  OG  . SER A 1 98  ? -3.515  -39.049 26.249  1   48.93  ? 94  SER A OG  1 
ATOM   791  N  N   . ALA A 1 99  ? -2.028  -41.066 22.752  1   59     ? 95  ALA A N   1 
ATOM   792  C  CA  . ALA A 1 99  ? -1.817  -41.483 21.378  1   57.36  ? 95  ALA A CA  1 
ATOM   793  C  C   . ALA A 1 99  ? -0.363  -41.919 21.161  1   61.42  ? 95  ALA A C   1 
ATOM   794  O  O   . ALA A 1 99  ? 0.282   -41.56  20.183  1   61.87  ? 95  ALA A O   1 
ATOM   795  C  CB  . ALA A 1 99  ? -2.25   -40.366 20.443  1   51.19  ? 95  ALA A CB  1 
ATOM   796  N  N   . LEU A 1 100 ? 0.141   -42.735 22.094  1   73.12  ? 96  LEU A N   1 
ATOM   797  C  CA  . LEU A 1 100 ? 1.512   -43.221 22.056  1   71.36  ? 96  LEU A CA  1 
ATOM   798  C  C   . LEU A 1 100 ? 1.59    -44.57  21.341  1   71.43  ? 96  LEU A C   1 
ATOM   799  O  O   . LEU A 1 100 ? 2.609   -44.901 20.745  1   62.05  ? 96  LEU A O   1 
ATOM   800  C  CB  . LEU A 1 100 ? 2.036   -43.334 23.493  1   74.68  ? 96  LEU A CB  1 
ATOM   801  C  CG  . LEU A 1 100 ? 1.812   -42.093 24.369  1   76.84  ? 96  LEU A CG  1 
ATOM   802  C  CD1 . LEU A 1 100 ? 2.5     -42.226 25.73   1   76.01  ? 96  LEU A CD1 1 
ATOM   803  C  CD2 . LEU A 1 100 ? 2.28    -40.845 23.636  1   80.33  ? 96  LEU A CD2 1 
ATOM   804  N  N   . THR A 1 101 ? 0.508   -45.355 21.451  1   76.2   ? 97  THR A N   1 
ATOM   805  C  CA  . THR A 1 101 ? 0.236   -46.509 20.606  1   70.86  ? 97  THR A CA  1 
ATOM   806  C  C   . THR A 1 101 ? -0.822  -46.209 19.538  1   64.39  ? 97  THR A C   1 
ATOM   807  O  O   . THR A 1 101 ? -1.216  -47.082 18.762  1   64.86  ? 97  THR A O   1 
ATOM   808  C  CB  . THR A 1 101 ? -0.224  -47.661 21.502  1   75.69  ? 97  THR A CB  1 
ATOM   809  O  OG1 . THR A 1 101 ? -1.323  -47.176 22.287  1   85.56  ? 97  THR A OG1 1 
ATOM   810  C  CG2 . THR A 1 101 ? 0.893   -48.172 22.397  1   74.84  ? 97  THR A CG2 1 
ATOM   811  N  N   . GLY A 1 102 ? -1.329  -44.974 19.526  1   52.49  ? 98  GLY A N   1 
ATOM   812  C  CA  . GLY A 1 102 ? -2.125  -44.483 18.415  1   46.71  ? 98  GLY A CA  1 
ATOM   813  C  C   . GLY A 1 102 ? -3.391  -43.77  18.878  1   44.64  ? 98  GLY A C   1 
ATOM   814  O  O   . GLY A 1 102 ? -3.713  -43.774 20.068  1   39.5   ? 98  GLY A O   1 
ATOM   815  N  N   . ILE A 1 103 ? -4.097  -43.164 17.915  1   41.07  ? 99  ILE A N   1 
ATOM   816  C  CA  . ILE A 1 103 ? -5.482  -42.747 18.102  1   42.19  ? 99  ILE A CA  1 
ATOM   817  C  C   . ILE A 1 103 ? -6.372  -43.849 17.531  1   36.91  ? 99  ILE A C   1 
ATOM   818  O  O   . ILE A 1 103 ? -6.238  -44.196 16.361  1   36.79  ? 99  ILE A O   1 
ATOM   819  C  CB  . ILE A 1 103 ? -5.785  -41.383 17.431  1   42.49  ? 99  ILE A CB  1 
ATOM   820  C  CG1 . ILE A 1 103 ? -4.818  -40.293 17.897  1   44.23  ? 99  ILE A CG1 1 
ATOM   821  C  CG2 . ILE A 1 103 ? -7.244  -40.964 17.656  1   44.57  ? 99  ILE A CG2 1 
ATOM   822  C  CD1 . ILE A 1 103 ? -5.003  -38.949 17.212  1   47.31  ? 99  ILE A CD1 1 
ATOM   823  N  N   . PRO A 1 104 ? -7.313  -44.433 18.311  1   35.14  ? 100 PRO A N   1 
ATOM   824  C  CA  . PRO A 1 104 ? -8.163  -45.502 17.781  1   33.15  ? 100 PRO A CA  1 
ATOM   825  C  C   . PRO A 1 104 ? -8.996  -44.978 16.615  1   32.09  ? 100 PRO A C   1 
ATOM   826  O  O   . PRO A 1 104 ? -9.363  -43.806 16.589  1   31.74  ? 100 PRO A O   1 
ATOM   827  C  CB  . PRO A 1 104 ? -9.007  -45.931 18.983  1   36.36  ? 100 PRO A CB  1 
ATOM   828  C  CG  . PRO A 1 104 ? -8.893  -44.796 19.989  1   37.25  ? 100 PRO A CG  1 
ATOM   829  C  CD  . PRO A 1 104 ? -7.616  -44.071 19.707  1   36.48  ? 100 PRO A CD  1 
ATOM   830  N  N   . LEU A 1 105 ? -9.268  -45.85  15.647  1   34.67  ? 101 LEU A N   1 
ATOM   831  C  CA  . LEU A 1 105 ? -9.916  -45.464 14.404  1   37.45  ? 101 LEU A CA  1 
ATOM   832  C  C   . LEU A 1 105 ? -11.284 -44.809 14.623  1   34.65  ? 101 LEU A C   1 
ATOM   833  O  O   . LEU A 1 105 ? -11.566 -43.801 13.985  1   35.66  ? 101 LEU A O   1 
ATOM   834  C  CB  . LEU A 1 105 ? -9.998  -46.718 13.482  1   37.62  ? 101 LEU A CB  1 
ATOM   835  C  CG  . LEU A 1 105 ? -10.383 -46.511 12.001  1   41.96  ? 101 LEU A CG  1 
ATOM   836  C  CD1 . LEU A 1 105 ? -9.437  -45.53  11.267  1   40.33  ? 101 LEU A CD1 1 
ATOM   837  C  CD2 . LEU A 1 105 ? -10.393 -47.827 11.272  1   43.18  ? 101 LEU A CD2 1 
ATOM   838  N  N   . PRO A 1 106 ? -12.162 -45.313 15.528  1   34.51  ? 102 PRO A N   1 
ATOM   839  C  CA  . PRO A 1 106 ? -13.43  -44.64  15.829  1   33.99  ? 102 PRO A CA  1 
ATOM   840  C  C   . PRO A 1 106 ? -13.301 -43.161 16.17   1   32.87  ? 102 PRO A C   1 
ATOM   841  O  O   . PRO A 1 106 ? -14.116 -42.34  15.749  1   36.67  ? 102 PRO A O   1 
ATOM   842  C  CB  . PRO A 1 106 ? -13.97  -45.431 17.038  1   36.62  ? 102 PRO A CB  1 
ATOM   843  C  CG  . PRO A 1 106 ? -13.373 -46.825 16.873  1   35.17  ? 102 PRO A CG  1 
ATOM   844  C  CD  . PRO A 1 106 ? -12.004 -46.573 16.283  1   36.32  ? 102 PRO A CD  1 
ATOM   845  N  N   . LEU A 1 107 ? -12.255 -42.824 16.927  1   31.75  ? 103 LEU A N   1 
ATOM   846  C  CA  . LEU A 1 107 ? -12.033 -41.449 17.34   1   32.37  ? 103 LEU A CA  1 
ATOM   847  C  C   . LEU A 1 107 ? -11.485 -40.602 16.195  1   30.3   ? 103 LEU A C   1 
ATOM   848  O  O   . LEU A 1 107 ? -11.802 -39.421 16.094  1   29.58  ? 103 LEU A O   1 
ATOM   849  C  CB  . LEU A 1 107 ? -11.089 -41.421 18.547  1   33.04  ? 103 LEU A CB  1 
ATOM   850  C  CG  . LEU A 1 107 ? -11.013 -40.106 19.314  1   35.38  ? 103 LEU A CG  1 
ATOM   851  C  CD1 . LEU A 1 107 ? -12.401 -39.669 19.876  1   32.82  ? 103 LEU A CD1 1 
ATOM   852  C  CD2 . LEU A 1 107 ? -10.048 -40.234 20.5    1   38.12  ? 103 LEU A CD2 1 
ATOM   853  N  N   . ILE A 1 108 ? -10.66  -41.213 15.335  1   32.28  ? 104 ILE A N   1 
ATOM   854  C  CA  . ILE A 1 108 ? -10.159 -40.551 14.137  1   31.66  ? 104 ILE A CA  1 
ATOM   855  C  C   . ILE A 1 108 ? -11.33  -40.191 13.227  1   28.74  ? 104 ILE A C   1 
ATOM   856  O  O   . ILE A 1 108 ? -11.424 -39.069 12.734  1   30.54  ? 104 ILE A O   1 
ATOM   857  C  CB  . ILE A 1 108 ? -9.111  -41.43  13.395  1   31.78  ? 104 ILE A CB  1 
ATOM   858  C  CG1 . ILE A 1 108 ? -7.831  -41.591 14.249  1   34.01  ? 104 ILE A CG1 1 
ATOM   859  C  CG2 . ILE A 1 108 ? -8.791  -40.85  12.011  1   31.94  ? 104 ILE A CG2 1 
ATOM   860  C  CD1 . ILE A 1 108 ? -6.734  -42.519 13.65   1   32.62  ? 104 ILE A CD1 1 
ATOM   861  N  N   . LYS A 1 109 ? -12.214 -41.168 13.021  1   28.39  ? 105 LYS A N   1 
ATOM   862  C  CA  . LYS A 1 109 ? -13.418 -40.986 12.232  1   28.81  ? 105 LYS A CA  1 
ATOM   863  C  C   . LYS A 1 109 ? -14.307 -39.885 12.787  1   23.85  ? 105 LYS A C   1 
ATOM   864  O  O   . LYS A 1 109 ? -14.699 -38.996 12.038  1   30.15  ? 105 LYS A O   1 
ATOM   865  C  CB  . LYS A 1 109 ? -14.236 -42.283 12.171  1   29.07  ? 105 LYS A CB  1 
ATOM   866  C  CG  . LYS A 1 109 ? -13.915 -43.133 11.009  1   31.23  ? 105 LYS A CG  1 
ATOM   867  C  CD  . LYS A 1 109 ? -14.642 -44.468 11.045  1   31.92  ? 105 LYS A CD  1 
ATOM   868  C  CE  . LYS A 1 109 ? -13.979 -45.404 10.076  1   31.19  ? 105 LYS A CE  1 
ATOM   869  N  NZ  . LYS A 1 109 ? -14.583 -46.737 10.082  1   33.06  ? 105 LYS A NZ  1 
ATOM   870  N  N   . SER A 1 110 ? -14.632 -39.975 14.079  0.5 19.36  ? 106 SER A N   1 
ATOM   871  C  CA  . SER A 1 110 ? -15.459 -38.979 14.735  0.5 17.9   ? 106 SER A CA  1 
ATOM   872  C  C   . SER A 1 110 ? -14.882 -37.583 14.531  0.5 17.67  ? 106 SER A C   1 
ATOM   873  O  O   . SER A 1 110 ? -15.585 -36.656 14.149  0.5 14.85  ? 106 SER A O   1 
ATOM   874  C  CB  . SER A 1 110 ? -15.575 -39.296 16.219  0.5 17.44  ? 106 SER A CB  1 
ATOM   875  O  OG  . SER A 1 110 ? -16.157 -38.218 16.924  0.5 17.31  ? 106 SER A OG  1 
ATOM   876  N  N   . TYR A 1 111 ? -13.572 -37.465 14.741  1   22.75  ? 107 TYR A N   1 
ATOM   877  C  CA  . TYR A 1 111 ? -12.899 -36.177 14.677  1   27.08  ? 107 TYR A CA  1 
ATOM   878  C  C   . TYR A 1 111 ? -12.903 -35.612 13.262  1   28.94  ? 107 TYR A C   1 
ATOM   879  O  O   . TYR A 1 111 ? -13.209 -34.438 13.07   1   30.55  ? 107 TYR A O   1 
ATOM   880  C  CB  . TYR A 1 111 ? -11.446 -36.263 15.189  1   29.49  ? 107 TYR A CB  1 
ATOM   881  C  CG  . TYR A 1 111 ? -11.231 -36.204 16.694  1   33.88  ? 107 TYR A CG  1 
ATOM   882  C  CD1 . TYR A 1 111 ? -12.285 -35.943 17.565  1   33     ? 107 TYR A CD1 1 
ATOM   883  C  CD2 . TYR A 1 111 ? -9.967  -36.402 17.244  1   34.14  ? 107 TYR A CD2 1 
ATOM   884  C  CE1 . TYR A 1 111 ? -12.083 -35.871 18.936  1   36.59  ? 107 TYR A CE1 1 
ATOM   885  C  CE2 . TYR A 1 111 ? -9.757  -36.336 18.614  1   35.95  ? 107 TYR A CE2 1 
ATOM   886  C  CZ  . TYR A 1 111 ? -10.817 -36.078 19.456  1   36.95  ? 107 TYR A CZ  1 
ATOM   887  O  OH  . TYR A 1 111 ? -10.613 -36.005 20.8    1   37.63  ? 107 TYR A OH  1 
ATOM   888  N  N   . LEU A 1 112 ? -12.552 -36.45  12.276  1   29     ? 108 LEU A N   1 
ATOM   889  C  CA  . LEU A 1 112 ? -12.528 -35.99  10.899  1   28.55  ? 108 LEU A CA  1 
ATOM   890  C  C   . LEU A 1 112 ? -13.931 -35.552 10.474  1   29.02  ? 108 LEU A C   1 
ATOM   891  O  O   . LEU A 1 112 ? -14.091 -34.528 9.813   1   28.06  ? 108 LEU A O   1 
ATOM   892  C  CB  . LEU A 1 112 ? -11.966 -37.068 9.964   1   27.25  ? 108 LEU A CB  1 
ATOM   893  C  CG  . LEU A 1 112 ? -11.761 -36.628 8.537   1   27.04  ? 108 LEU A CG  1 
ATOM   894  C  CD1 . LEU A 1 112 ? -10.878 -35.362 8.457   1   27.47  ? 108 LEU A CD1 1 
ATOM   895  C  CD2 . LEU A 1 112 ? -11.152 -37.777 7.708   1   28.29  ? 108 LEU A CD2 1 
ATOM   896  N  N   . PHE A 1 113 ? -14.943 -36.331 10.875  1   29.56  ? 109 PHE A N   1 
ATOM   897  C  CA  . PHE A 1 113 ? -16.327 -36.034 10.535  1   31.37  ? 109 PHE A CA  1 
ATOM   898  C  C   . PHE A 1 113 ? -16.76  -34.679 11.094  1   30.07  ? 109 PHE A C   1 
ATOM   899  O  O   . PHE A 1 113 ? -17.383 -33.873 10.405  1   29.7   ? 109 PHE A O   1 
ATOM   900  C  CB  . PHE A 1 113 ? -17.235 -37.142 11.074  1   33.06  ? 109 PHE A CB  1 
ATOM   901  C  CG  . PHE A 1 113 ? -18.621 -37.18  10.467  1   34.67  ? 109 PHE A CG  1 
ATOM   902  C  CD1 . PHE A 1 113 ? -18.795 -37.39  9.115   1   33.14  ? 109 PHE A CD1 1 
ATOM   903  C  CD2 . PHE A 1 113 ? -19.751 -37.024 11.258  1   36.1   ? 109 PHE A CD2 1 
ATOM   904  C  CE1 . PHE A 1 113 ? -20.071 -37.432 8.561   1   34.63  ? 109 PHE A CE1 1 
ATOM   905  C  CE2 . PHE A 1 113 ? -21.019 -37.072 10.703  1   36.78  ? 109 PHE A CE2 1 
ATOM   906  C  CZ  . PHE A 1 113 ? -21.172 -37.286 9.359   1   37.06  ? 109 PHE A CZ  1 
ATOM   907  N  N   . GLN A 1 114 ? -16.378 -34.421 12.346  1   29.33  ? 110 GLN A N   1 
ATOM   908  C  CA  . GLN A 1 114 ? -16.681 -33.151 12.984  1   29.57  ? 110 GLN A CA  1 
ATOM   909  C  C   . GLN A 1 114 ? -15.941 -31.999 12.312  1   28.72  ? 110 GLN A C   1 
ATOM   910  O  O   . GLN A 1 114 ? -16.523 -30.946 12.082  1   27.09  ? 110 GLN A O   1 
ATOM   911  C  CB  . GLN A 1 114 ? -16.331 -33.211 14.47   1   28.16  ? 110 GLN A CB  1 
ATOM   912  C  CG  . GLN A 1 114 ? -17.286 -34.045 15.285  1   26.99  ? 110 GLN A CG  1 
ATOM   913  C  CD  . GLN A 1 114 ? -16.919 -33.949 16.741  1   30.72  ? 110 GLN A CD  1 
ATOM   914  O  OE1 . GLN A 1 114 ? -17.103 -32.893 17.378  1   29.51  ? 110 GLN A OE1 1 
ATOM   915  N  NE2 . GLN A 1 114 ? -16.359 -35.029 17.297  1   30.98  ? 110 GLN A NE2 1 
ATOM   916  N  N   . LEU A 1 115 ? -14.651 -32.21  12.015  1   29.29  ? 111 LEU A N   1 
ATOM   917  C  CA  . LEU A 1 115 ? -13.849 -31.193 11.353  1   29.04  ? 111 LEU A CA  1 
ATOM   918  C  C   . LEU A 1 115 ? -14.47  -30.811 10.012  1   28.88  ? 111 LEU A C   1 
ATOM   919  O  O   . LEU A 1 115 ? -14.521 -29.633 9.67    1   28.2   ? 111 LEU A O   1 
ATOM   920  C  CB  . LEU A 1 115 ? -12.428 -31.682 11.148  1   29.08  ? 111 LEU A CB  1 
ATOM   921  C  CG  . LEU A 1 115 ? -11.59  -31.785 12.407  1   32.78  ? 111 LEU A CG  1 
ATOM   922  C  CD1 . LEU A 1 115 ? -10.247 -32.427 12.111  1   32.25  ? 111 LEU A CD1 1 
ATOM   923  C  CD2 . LEU A 1 115 ? -11.393 -30.426 13.05   1   33.58  ? 111 LEU A CD2 1 
ATOM   924  N  N   . LEU A 1 116 ? -14.968 -31.814 9.28    1   29.08  ? 112 LEU A N   1 
ATOM   925  C  CA  . LEU A 1 116 ? -15.621 -31.583 8.001   1   32.44  ? 112 LEU A CA  1 
ATOM   926  C  C   . LEU A 1 116 ? -16.937 -30.824 8.136   1   31.59  ? 112 LEU A C   1 
ATOM   927  O  O   . LEU A 1 116 ? -17.254 -29.99  7.286   1   34.35  ? 112 LEU A O   1 
ATOM   928  C  CB  . LEU A 1 116 ? -15.87  -32.917 7.286   1   32.22  ? 112 LEU A CB  1 
ATOM   929  C  CG  . LEU A 1 116 ? -14.613 -33.565 6.705   1   29.79  ? 112 LEU A CG  1 
ATOM   930  C  CD1 . LEU A 1 116 ? -14.855 -35.017 6.366   1   31.04  ? 112 LEU A CD1 1 
ATOM   931  C  CD2 . LEU A 1 116 ? -14.136 -32.846 5.476   1   29.49  ? 112 LEU A CD2 1 
ATOM   932  N  N   . GLN A 1 117 ? -17.69  -31.107 9.207   1   30.17  ? 113 GLN A N   1 
ATOM   933  C  CA  . GLN A 1 117 ? -18.906 -30.356 9.48    1   30.57  ? 113 GLN A CA  1 
ATOM   934  C  C   . GLN A 1 117 ? -18.604 -28.883 9.756   1   30.24  ? 113 GLN A C   1 
ATOM   935  O  O   . GLN A 1 117 ? -19.29  -27.992 9.258   1   25.86  ? 113 GLN A O   1 
ATOM   936  C  CB  . GLN A 1 117 ? -19.657 -30.927 10.671  1   32.61  ? 113 GLN A CB  1 
ATOM   937  C  CG  . GLN A 1 117 ? -20.366 -32.229 10.4    1   33.33  ? 113 GLN A CG  1 
ATOM   938  C  CD  . GLN A 1 117 ? -21.087 -32.669 11.631  1   30.81  ? 113 GLN A CD  1 
ATOM   939  O  OE1 . GLN A 1 117 ? -22.038 -32.026 12.119  1   29.77  ? 113 GLN A OE1 1 
ATOM   940  N  NE2 . GLN A 1 117 ? -20.664 -33.783 12.135  1   31.63  ? 113 GLN A NE2 1 
ATOM   941  N  N   . GLY A 1 118 ? -17.577 -28.638 10.574  1   33.5   ? 114 GLY A N   1 
ATOM   942  C  CA  . GLY A 1 118 ? -17.152 -27.284 10.885  1   32.87  ? 114 GLY A CA  1 
ATOM   943  C  C   . GLY A 1 118 ? -16.73  -26.518 9.639   1   30.81  ? 114 GLY A C   1 
ATOM   944  O  O   . GLY A 1 118 ? -17.159 -25.387 9.415   1   30.44  ? 114 GLY A O   1 
ATOM   945  N  N   . LEU A 1 119 ? -15.92  -27.181 8.814   1   32.94  ? 115 LEU A N   1 
ATOM   946  C  CA  . LEU A 1 119 ? -15.367 -26.565 7.622   1   30.72  ? 115 LEU A CA  1 
ATOM   947  C  C   . LEU A 1 119 ? -16.442 -26.285 6.569   1   30.59  ? 115 LEU A C   1 
ATOM   948  O  O   . LEU A 1 119 ? -16.449 -25.208 5.967   1   32.53  ? 115 LEU A O   1 
ATOM   949  C  CB  . LEU A 1 119 ? -14.25  -27.445 7.058   1   27.64  ? 115 LEU A CB  1 
ATOM   950  C  CG  . LEU A 1 119 ? -13.506 -26.839 5.871   1   29.51  ? 115 LEU A CG  1 
ATOM   951  C  CD1 . LEU A 1 119 ? -12.843 -25.514 6.249   1   29.29  ? 115 LEU A CD1 1 
ATOM   952  C  CD2 . LEU A 1 119 ? -12.475 -27.807 5.338   1   31.94  ? 115 LEU A CD2 1 
ATOM   953  N  N   . ALA A 1 120 ? -17.358 -27.246 6.371   1   28.39  ? 116 ALA A N   1 
ATOM   954  C  CA  . ALA A 1 120 ? -18.479 -27.043 5.465   1   28.66  ? 116 ALA A CA  1 
ATOM   955  C  C   . ALA A 1 120 ? -19.297 -25.807 5.847   1   25.76  ? 116 ALA A C   1 
ATOM   956  O  O   . ALA A 1 120 ? -19.748 -25.064 4.981   1   25.67  ? 116 ALA A O   1 
ATOM   957  C  CB  . ALA A 1 120 ? -19.365 -28.273 5.439   1   26.92  ? 116 ALA A CB  1 
ATOM   958  N  N   . PHE A 1 121 ? -19.488 -25.604 7.157   1   24.86  ? 117 PHE A N   1 
ATOM   959  C  CA  . PHE A 1 121 ? -20.225 -24.459 7.66    1   24.63  ? 117 PHE A CA  1 
ATOM   960  C  C   . PHE A 1 121 ? -19.472 -23.169 7.34    1   25.62  ? 117 PHE A C   1 
ATOM   961  O  O   . PHE A 1 121 ? -20.089 -22.199 6.93    1   28.44  ? 117 PHE A O   1 
ATOM   962  C  CB  . PHE A 1 121 ? -20.48  -24.606 9.166   1   26.34  ? 117 PHE A CB  1 
ATOM   963  C  CG  . PHE A 1 121 ? -21.443 -23.589 9.732   1   25.14  ? 117 PHE A CG  1 
ATOM   964  C  CD1 . PHE A 1 121 ? -21.006 -22.332 10.113  1   23.44  ? 117 PHE A CD1 1 
ATOM   965  C  CD2 . PHE A 1 121 ? -22.8   -23.869 9.819   1   25.91  ? 117 PHE A CD2 1 
ATOM   966  C  CE1 . PHE A 1 121 ? -21.902 -21.388 10.601  1   24.54  ? 117 PHE A CE1 1 
ATOM   967  C  CE2 . PHE A 1 121 ? -23.7   -22.924 10.314  1   24.16  ? 117 PHE A CE2 1 
ATOM   968  C  CZ  . PHE A 1 121 ? -23.25  -21.695 10.719  1   23.18  ? 117 PHE A CZ  1 
ATOM   969  N  N   . CYS A 1 122 ? -18.14  -23.169 7.489   1   26.48  ? 118 CYS A N   1 
ATOM   970  C  CA  . CYS A 1 122 ? -17.342 -22.015 7.112   1   29.17  ? 118 CYS A CA  1 
ATOM   971  C  C   . CYS A 1 122 ? -17.559 -21.652 5.649   1   29.04  ? 118 CYS A C   1 
ATOM   972  O  O   . CYS A 1 122 ? -17.879 -20.506 5.33    1   27.29  ? 118 CYS A O   1 
ATOM   973  C  CB  . CYS A 1 122 ? -15.863 -22.236 7.395   1   29.3   ? 118 CYS A CB  1 
ATOM   974  S  SG  . CYS A 1 122 ? -15.469 -22.357 9.147   1   30.19  ? 118 CYS A SG  1 
ATOM   975  N  N   . HIS A 1 123 ? -17.385 -22.65  4.78    1   28.36  ? 119 HIS A N   1 
ATOM   976  C  CA  . HIS A 1 123 ? -17.457 -22.449 3.346   1   27.37  ? 119 HIS A CA  1 
ATOM   977  C  C   . HIS A 1 123 ? -18.862 -22.044 2.91    1   28.57  ? 119 HIS A C   1 
ATOM   978  O  O   . HIS A 1 123 ? -19.01  -21.192 2.034   1   29.33  ? 119 HIS A O   1 
ATOM   979  C  CB  . HIS A 1 123 ? -16.956 -23.713 2.628   1   28.02  ? 119 HIS A CB  1 
ATOM   980  C  CG  . HIS A 1 123 ? -15.497 -23.983 2.854   1   28.7   ? 119 HIS A CG  1 
ATOM   981  N  ND1 . HIS A 1 123 ? -14.907 -25.165 2.439   1   30.49  ? 119 HIS A ND1 1 
ATOM   982  C  CD2 . HIS A 1 123 ? -14.555 -23.21  3.452   1   27.84  ? 119 HIS A CD2 1 
ATOM   983  C  CE1 . HIS A 1 123 ? -13.626 -25.074 2.791   1   32.87  ? 119 HIS A CE1 1 
ATOM   984  N  NE2 . HIS A 1 123 ? -13.371 -23.904 3.404   1   29.26  ? 119 HIS A NE2 1 
ATOM   985  N  N   . SER A 1 124 ? -19.883 -22.627 3.547   1   25.63  ? 120 SER A N   1 
ATOM   986  C  CA  . SER A 1 124 ? -21.257 -22.221 3.314   1   29.41  ? 120 SER A CA  1 
ATOM   987  C  C   . SER A 1 124 ? -21.53  -20.774 3.72    1   30.1   ? 120 SER A C   1 
ATOM   988  O  O   . SER A 1 124 ? -22.506 -20.179 3.263   1   28.04  ? 120 SER A O   1 
ATOM   989  C  CB  . SER A 1 124 ? -22.219 -23.121 4.083   1   31.89  ? 120 SER A CB  1 
ATOM   990  O  OG  . SER A 1 124 ? -22.129 -24.452 3.612   1   36.7   ? 120 SER A OG  1 
ATOM   991  N  N   . HIS A 1 125 ? -20.695 -20.24  4.625   1   29.01  ? 121 HIS A N   1 
ATOM   992  C  CA  . HIS A 1 125 ? -20.797 -18.855 5.051   1   29.44  ? 121 HIS A CA  1 
ATOM   993  C  C   . HIS A 1 125 ? -19.647 -17.984 4.543   1   30.04  ? 121 HIS A C   1 
ATOM   994  O  O   . HIS A 1 125 ? -19.257 -17.027 5.203   1   28.91  ? 121 HIS A O   1 
ATOM   995  C  CB  . HIS A 1 125 ? -20.9   -18.825 6.564   1   29.27  ? 121 HIS A CB  1 
ATOM   996  C  CG  . HIS A 1 125 ? -22.151 -19.485 7.043   1   29.06  ? 121 HIS A CG  1 
ATOM   997  N  ND1 . HIS A 1 125 ? -22.349 -20.838 6.887   1   29.68  ? 121 HIS A ND1 1 
ATOM   998  C  CD2 . HIS A 1 125 ? -23.243 -18.944 7.617   1   29.24  ? 121 HIS A CD2 1 
ATOM   999  C  CE1 . HIS A 1 125 ? -23.55  -21.088 7.391   1   30.74  ? 121 HIS A CE1 1 
ATOM   1000 N  NE2 . HIS A 1 125 ? -24.123 -19.97  7.833   1   30.61  ? 121 HIS A NE2 1 
ATOM   1001 N  N   . ARG A 1 126 ? -19.142 -18.277 3.345   1   28.23  ? 122 ARG A N   1 
ATOM   1002 C  CA  . ARG A 1 126 ? -18.119 -17.432 2.668   1   28.85  ? 122 ARG A CA  1 
ATOM   1003 C  C   . ARG A 1 126 ? -16.855 -17.182 3.524   1   28.96  ? 122 ARG A C   1 
ATOM   1004 O  O   . ARG A 1 126 ? -16.214 -16.147 3.331   1   28.81  ? 122 ARG A O   1 
ATOM   1005 C  CB  . ARG A 1 126 ? -18.928 -16.242 2.128   1   29.44  ? 122 ARG A CB  1 
ATOM   1006 C  CG  . ARG A 1 126 ? -18.649 -14.792 2.481   1   29.83  ? 122 ARG A CG  1 
ATOM   1007 C  CD  . ARG A 1 126 ? -19.806 -14.222 3.233   1   31.58  ? 122 ARG A CD  1 
ATOM   1008 N  NE  . ARG A 1 126 ? -19.26  -13.42  4.328   1   35.16  ? 122 ARG A NE  1 
ATOM   1009 C  CZ  . ARG A 1 126 ? -19.823 -13.349 5.514   1   30.42  ? 122 ARG A CZ  1 
ATOM   1010 N  NH1 . ARG A 1 126 ? -19.598 -14.296 6.402   1   25.78  ? 122 ARG A NH1 1 
ATOM   1011 N  NH2 . ARG A 1 126 ? -20.623 -12.341 5.794   1   31.8   ? 122 ARG A NH2 1 
ATOM   1012 N  N   . VAL A 1 127 ? -16.438 -18.142 4.348   1   28.55  ? 123 VAL A N   1 
ATOM   1013 C  CA  . VAL A 1 127 ? -15.199 -17.957 5.092   1   29.07  ? 123 VAL A CA  1 
ATOM   1014 C  C   . VAL A 1 127 ? -14.179 -19.047 4.768   1   28.35  ? 123 VAL A C   1 
ATOM   1015 O  O   . VAL A 1 127 ? -14.477 -20.228 4.912   1   27.12  ? 123 VAL A O   1 
ATOM   1016 C  CB  . VAL A 1 127 ? -15.485 -17.906 6.611   1   30.7   ? 123 VAL A CB  1 
ATOM   1017 C  CG1 . VAL A 1 127 ? -14.185 -17.925 7.429   1   30.49  ? 123 VAL A CG1 1 
ATOM   1018 C  CG2 . VAL A 1 127 ? -16.341 -16.687 6.968   1   30     ? 123 VAL A CG2 1 
ATOM   1019 N  N   . LEU A 1 128 ? -12.978 -18.637 4.334   1   28.59  ? 124 LEU A N   1 
ATOM   1020 C  CA  . LEU A 1 128 ? -11.823 -19.523 4.3     1   28.76  ? 124 LEU A CA  1 
ATOM   1021 C  C   . LEU A 1 128 ? -11.101 -19.423 5.642   1   29.87  ? 124 LEU A C   1 
ATOM   1022 O  O   . LEU A 1 128 ? -10.881 -18.319 6.142   1   33.6   ? 124 LEU A O   1 
ATOM   1023 C  CB  . LEU A 1 128 ? -10.821 -19.159 3.173   1   27.41  ? 124 LEU A CB  1 
ATOM   1024 C  CG  . LEU A 1 128 ? -11.349 -19.164 1.753   1   29.01  ? 124 LEU A CG  1 
ATOM   1025 C  CD1 . LEU A 1 128 ? -10.312 -18.672 0.766   1   30.4   ? 124 LEU A CD1 1 
ATOM   1026 C  CD2 . LEU A 1 128 ? -11.783 -20.503 1.33    1   28.24  ? 124 LEU A CD2 1 
ATOM   1027 N  N   . HIS A 1 129 ? -10.693 -20.575 6.192   1   29.14  ? 125 HIS A N   1 
ATOM   1028 C  CA  . HIS A 1 129 ? -9.936  -20.599 7.431   1   26.45  ? 125 HIS A CA  1 
ATOM   1029 C  C   . HIS A 1 129 ? -8.47   -20.227 7.209   1   25.96  ? 125 HIS A C   1 
ATOM   1030 O  O   . HIS A 1 129 ? -7.961  -19.301 7.83    1   24.69  ? 125 HIS A O   1 
ATOM   1031 C  CB  . HIS A 1 129 ? -10.064 -21.963 8.123   1   26.54  ? 125 HIS A CB  1 
ATOM   1032 C  CG  . HIS A 1 129 ? -9.432  -21.98  9.484   1   27.19  ? 125 HIS A CG  1 
ATOM   1033 N  ND1 . HIS A 1 129 ? -8.054  -22.099 9.643   1   25.48  ? 125 HIS A ND1 1 
ATOM   1034 C  CD2 . HIS A 1 129 ? -10.005 -21.882 10.699  1   27.4   ? 125 HIS A CD2 1 
ATOM   1035 C  CE1 . HIS A 1 129 ? -7.842  -22.057 10.946  1   27.25  ? 125 HIS A CE1 1 
ATOM   1036 N  NE2 . HIS A 1 129 ? -8.999  -21.92  11.618  1   27.8   ? 125 HIS A NE2 1 
ATOM   1037 N  N   . ARG A 1 130 ? -7.795  -20.983 6.341   1   30.04  ? 126 ARG A N   1 
ATOM   1038 C  CA  . ARG A 1 130 ? -6.457  -20.66  5.868   1   29.31  ? 126 ARG A CA  1 
ATOM   1039 C  C   . ARG A 1 130 ? -5.35   -20.881 6.893   1   31.16  ? 126 ARG A C   1 
ATOM   1040 O  O   . ARG A 1 130 ? -4.239  -20.401 6.689   1   35.45  ? 126 ARG A O   1 
ATOM   1041 C  CB  . ARG A 1 130 ? -6.362  -19.199 5.349   1   27.96  ? 126 ARG A CB  1 
ATOM   1042 C  CG  . ARG A 1 130 ? -7.338  -18.899 4.21    1   27.79  ? 126 ARG A CG  1 
ATOM   1043 C  CD  . ARG A 1 130 ? -6.957  -17.663 3.423   1   26.66  ? 126 ARG A CD  1 
ATOM   1044 N  NE  . ARG A 1 130 ? -6.943  -16.484 4.277   1   26.49  ? 126 ARG A NE  1 
ATOM   1045 C  CZ  . ARG A 1 130 ? -6.509  -15.288 3.904   1   28.18  ? 126 ARG A CZ  1 
ATOM   1046 N  NH1 . ARG A 1 130 ? -6.098  -15.05  2.674   1   30.12  ? 126 ARG A NH1 1 
ATOM   1047 N  NH2 . ARG A 1 130 ? -6.487  -14.304 4.794   1   29.37  ? 126 ARG A NH2 1 
ATOM   1048 N  N   . ASP A 1 131 ? -5.631  -21.632 7.962   1   31.05  ? 127 ASP A N   1 
ATOM   1049 C  CA  . ASP A 1 131 ? -4.575  -22.083 8.856   1   28.84  ? 127 ASP A CA  1 
ATOM   1050 C  C   . ASP A 1 131 ? -4.984  -23.341 9.618   1   28.22  ? 127 ASP A C   1 
ATOM   1051 O  O   . ASP A 1 131 ? -4.803  -23.434 10.831  1   26.94  ? 127 ASP A O   1 
ATOM   1052 C  CB  . ASP A 1 131 ? -4.161  -20.979 9.871   1   30.57  ? 127 ASP A CB  1 
ATOM   1053 C  CG  . ASP A 1 131 ? -2.731  -21.145 10.389  1   32.22  ? 127 ASP A CG  1 
ATOM   1054 O  OD1 . ASP A 1 131 ? -1.972  -21.919 9.795   1   36.06  ? 127 ASP A OD1 1 
ATOM   1055 O  OD2 . ASP A 1 131 ? -2.39   -20.522 11.383  1   38.51  ? 127 ASP A OD2 1 
ATOM   1056 N  N   . LEU A 1 132 ? -5.521  -24.322 8.897   1   26.93  ? 128 LEU A N   1 
ATOM   1057 C  CA  . LEU A 1 132 ? -5.946  -25.542 9.552   1   29.93  ? 128 LEU A CA  1 
ATOM   1058 C  C   . LEU A 1 132 ? -4.714  -26.389 9.861   1   30.13  ? 128 LEU A C   1 
ATOM   1059 O  O   . LEU A 1 132 ? -3.961  -26.772 8.964   1   29.25  ? 128 LEU A O   1 
ATOM   1060 C  CB  . LEU A 1 132 ? -6.951  -26.29  8.681   1   30.32  ? 128 LEU A CB  1 
ATOM   1061 C  CG  . LEU A 1 132 ? -8.3    -25.595 8.519   1   31.03  ? 128 LEU A CG  1 
ATOM   1062 C  CD1 . LEU A 1 132 ? -9.164  -26.354 7.531   1   33.53  ? 128 LEU A CD1 1 
ATOM   1063 C  CD2 . LEU A 1 132 ? -9.008  -25.43  9.868   1   32.31  ? 128 LEU A CD2 1 
ATOM   1064 N  N   . LYS A 1 133 ? -4.513  -26.646 11.151  1   27.06  ? 129 LYS A N   1 
ATOM   1065 C  CA  . LYS A 1 133 ? -3.428  -27.497 11.603  1   29.41  ? 129 LYS A CA  1 
ATOM   1066 C  C   . LYS A 1 133 ? -3.787  -27.978 13.001  1   30.97  ? 129 LYS A C   1 
ATOM   1067 O  O   . LYS A 1 133 ? -4.637  -27.378 13.649  1   32.09  ? 129 LYS A O   1 
ATOM   1068 C  CB  . LYS A 1 133 ? -2.123  -26.736 11.582  1   28.65  ? 129 LYS A CB  1 
ATOM   1069 C  CG  . LYS A 1 133 ? -2.168  -25.417 12.326  1   32.47  ? 129 LYS A CG  1 
ATOM   1070 C  CD  . LYS A 1 133 ? -0.79   -24.787 12.325  1   37.02  ? 129 LYS A CD  1 
ATOM   1071 C  CE  . LYS A 1 133 ? -0.695  -23.557 13.17   1   37.15  ? 129 LYS A CE  1 
ATOM   1072 N  NZ  . LYS A 1 133 ? 0.665   -22.965 13.101  1   36.79  ? 129 LYS A NZ  1 
ATOM   1073 N  N   . PRO A 1 134 ? -3.176  -29.068 13.512  1   32.93  ? 130 PRO A N   1 
ATOM   1074 C  CA  . PRO A 1 134 ? -3.622  -29.666 14.778  1   32.91  ? 130 PRO A CA  1 
ATOM   1075 C  C   . PRO A 1 134 ? -3.597  -28.721 15.978  1   33.13  ? 130 PRO A C   1 
ATOM   1076 O  O   . PRO A 1 134 ? -4.434  -28.846 16.869  1   35.59  ? 130 PRO A O   1 
ATOM   1077 C  CB  . PRO A 1 134 ? -2.679  -30.861 14.956  1   30.44  ? 130 PRO A CB  1 
ATOM   1078 C  CG  . PRO A 1 134 ? -2.202  -31.162 13.544  1   32     ? 130 PRO A CG  1 
ATOM   1079 C  CD  . PRO A 1 134 ? -2.081  -29.818 12.881  1   33.31  ? 130 PRO A CD  1 
ATOM   1080 N  N   . GLN A 1 135 ? -2.662  -27.762 15.965  1   32.07  ? 131 GLN A N   1 
ATOM   1081 C  CA  . GLN A 1 135 ? -2.536  -26.765 17.019  1   33.14  ? 131 GLN A CA  1 
ATOM   1082 C  C   . GLN A 1 135 ? -3.744  -25.828 17.098  1   33.13  ? 131 GLN A C   1 
ATOM   1083 O  O   . GLN A 1 135 ? -3.965  -25.19  18.134  1   26.69  ? 131 GLN A O   1 
ATOM   1084 C  CB  . GLN A 1 135 ? -1.276  -25.886 16.819  1   35.79  ? 131 GLN A CB  1 
ATOM   1085 C  CG  . GLN A 1 135 ? 0.093   -26.626 16.836  1   39.59  ? 131 GLN A CG  1 
ATOM   1086 C  CD  . GLN A 1 135 ? 0.453   -27.41  15.548  1   40.19  ? 131 GLN A CD  1 
ATOM   1087 O  OE1 . GLN A 1 135 ? -0.272  -27.454 14.554  1   40.11  ? 131 GLN A OE1 1 
ATOM   1088 N  NE2 . GLN A 1 135 ? 1.591   -28.072 15.545  1   42.17  ? 131 GLN A NE2 1 
ATOM   1089 N  N   . ASN A 1 136 ? -4.49   -25.719 15.984  1   28.11  ? 132 ASN A N   1 
ATOM   1090 C  CA  . ASN A 1 136 ? -5.645  -24.84  15.903  1   29.67  ? 132 ASN A CA  1 
ATOM   1091 C  C   . ASN A 1 136 ? -6.975  -25.598 15.946  1   29.81  ? 132 ASN A C   1 
ATOM   1092 O  O   . ASN A 1 136 ? -8.017  -25.022 15.656  1   30.21  ? 132 ASN A O   1 
ATOM   1093 C  CB  . ASN A 1 136 ? -5.548  -24.003 14.628  1   30.43  ? 132 ASN A CB  1 
ATOM   1094 C  CG  . ASN A 1 136 ? -4.463  -22.973 14.654  1   30.06  ? 132 ASN A CG  1 
ATOM   1095 O  OD1 . ASN A 1 136 ? -3.902  -22.662 15.696  1   29.99  ? 132 ASN A OD1 1 
ATOM   1096 N  ND2 . ASN A 1 136 ? -4.136  -22.412 13.49   1   28.75  ? 132 ASN A ND2 1 
ATOM   1097 N  N   . LEU A 1 137 ? -6.921  -26.891 16.297  1   30.05  ? 133 LEU A N   1 
ATOM   1098 C  CA  . LEU A 1 137 ? -8.11   -27.704 16.488  1   28.2   ? 133 LEU A CA  1 
ATOM   1099 C  C   . LEU A 1 137 ? -8.177  -28.123 17.957  1   29.16  ? 133 LEU A C   1 
ATOM   1100 O  O   . LEU A 1 137 ? -7.28   -28.804 18.47   1   30.18  ? 133 LEU A O   1 
ATOM   1101 C  CB  . LEU A 1 137 ? -8.062  -28.918 15.578  1   29.42  ? 133 LEU A CB  1 
ATOM   1102 C  CG  . LEU A 1 137 ? -7.717  -28.645 14.118  1   30.89  ? 133 LEU A CG  1 
ATOM   1103 C  CD1 . LEU A 1 137 ? -7.622  -29.945 13.331  1   32.45  ? 133 LEU A CD1 1 
ATOM   1104 C  CD2 . LEU A 1 137 ? -8.699  -27.728 13.481  1   28.85  ? 133 LEU A CD2 1 
ATOM   1105 N  N   . LEU A 1 138 ? -9.246  -27.686 18.63   1   26.47  ? 134 LEU A N   1 
ATOM   1106 C  CA  . LEU A 1 138 ? -9.395  -27.855 20.064  1   28.31  ? 134 LEU A CA  1 
ATOM   1107 C  C   . LEU A 1 138 ? -10.391 -28.974 20.377  1   29.3   ? 134 LEU A C   1 
ATOM   1108 O  O   . LEU A 1 138 ? -11.406 -29.114 19.696  1   30.8   ? 134 LEU A O   1 
ATOM   1109 C  CB  . LEU A 1 138 ? -9.853  -26.518 20.662  1   28     ? 134 LEU A CB  1 
ATOM   1110 C  CG  . LEU A 1 138 ? -8.983  -25.309 20.281  1   30.61  ? 134 LEU A CG  1 
ATOM   1111 C  CD1 . LEU A 1 138 ? -9.437  -24.059 20.986  1   30.96  ? 134 LEU A CD1 1 
ATOM   1112 C  CD2 . LEU A 1 138 ? -7.479  -25.524 20.614  1   31.32  ? 134 LEU A CD2 1 
ATOM   1113 N  N   . ILE A 1 139 ? -10.058 -29.781 21.387  1   28.46  ? 135 ILE A N   1 
ATOM   1114 C  CA  . ILE A 1 139 ? -10.886 -30.886 21.839  1   29.24  ? 135 ILE A CA  1 
ATOM   1115 C  C   . ILE A 1 139 ? -11.298 -30.645 23.287  1   26.65  ? 135 ILE A C   1 
ATOM   1116 O  O   . ILE A 1 139 ? -10.547 -30.045 24.057  1   26.55  ? 135 ILE A O   1 
ATOM   1117 C  CB  . ILE A 1 139 ? -10.17  -32.242 21.699  1   30.54  ? 135 ILE A CB  1 
ATOM   1118 C  CG1 . ILE A 1 139 ? -8.925  -32.315 22.56   1   35.51  ? 135 ILE A CG1 1 
ATOM   1119 C  CG2 . ILE A 1 139 ? -9.815  -32.533 20.261  1   31.69  ? 135 ILE A CG2 1 
ATOM   1120 C  CD1 . ILE A 1 139 ? -8.277  -33.714 22.606  1   38.29  ? 135 ILE A CD1 1 
ATOM   1121 N  N   . ASN A 1 140 ? -12.5   -31.103 23.642  1   26.26  ? 136 ASN A N   1 
ATOM   1122 C  CA  . ASN A 1 140 ? -12.967 -31.066 25.02   1   28.11  ? 136 ASN A CA  1 
ATOM   1123 C  C   . ASN A 1 140 ? -13.056 -32.475 25.608  1   30.67  ? 136 ASN A C   1 
ATOM   1124 O  O   . ASN A 1 140 ? -12.671 -33.44  24.964  1   31.89  ? 136 ASN A O   1 
ATOM   1125 C  CB  . ASN A 1 140 ? -14.295 -30.328 25.117  1   26.95  ? 136 ASN A CB  1 
ATOM   1126 C  CG  . ASN A 1 140 ? -15.429 -31.006 24.437  1   28.13  ? 136 ASN A CG  1 
ATOM   1127 O  OD1 . ASN A 1 140 ? -15.409 -32.202 24.113  1   31.07  ? 136 ASN A OD1 1 
ATOM   1128 N  ND2 . ASN A 1 140 ? -16.468 -30.256 24.226  1   30.91  ? 136 ASN A ND2 1 
ATOM   1129 N  N   . THR A 1 141 ? -13.535 -32.591 26.85   1   35     ? 137 THR A N   1 
ATOM   1130 C  CA  . THR A 1 141 ? -13.611 -33.88  27.523  1   38.36  ? 137 THR A CA  1 
ATOM   1131 C  C   . THR A 1 141 ? -14.772 -34.751 27.04   1   41.22  ? 137 THR A C   1 
ATOM   1132 O  O   . THR A 1 141 ? -14.817 -35.937 27.361  1   46.2   ? 137 THR A O   1 
ATOM   1133 C  CB  . THR A 1 141 ? -13.699 -33.66  29.039  1   37.39  ? 137 THR A CB  1 
ATOM   1134 O  OG1 . THR A 1 141 ? -14.837 -32.866 29.31   1   37.48  ? 137 THR A OG1 1 
ATOM   1135 C  CG2 . THR A 1 141 ? -12.484 -32.969 29.595  1   40.55  ? 137 THR A CG2 1 
ATOM   1136 N  N   . GLU A 1 142 ? -15.691 -34.165 26.265  1   40.38  ? 138 GLU A N   1 
ATOM   1137 C  CA  . GLU A 1 142 ? -16.879 -34.859 25.794  1   45.35  ? 138 GLU A CA  1 
ATOM   1138 C  C   . GLU A 1 142 ? -16.736 -35.544 24.432  1   43.92  ? 138 GLU A C   1 
ATOM   1139 O  O   . GLU A 1 142 ? -17.636 -36.268 24.011  1   42.45  ? 138 GLU A O   1 
ATOM   1140 C  CB  . GLU A 1 142 ? -18.049 -33.854 25.707  1   48.32  ? 138 GLU A CB  1 
ATOM   1141 C  CG  . GLU A 1 142 ? -18.533 -33.364 27.051  1   48.75  ? 138 GLU A CG  1 
ATOM   1142 C  CD  . GLU A 1 142 ? -19.145 -34.467 27.885  1   52.68  ? 138 GLU A CD  1 
ATOM   1143 O  OE1 . GLU A 1 142 ? -20.098 -35.123 27.401  1   52.54  ? 138 GLU A OE1 1 
ATOM   1144 O  OE2 . GLU A 1 142 ? -18.652 -34.698 29.013  1   59.37  ? 138 GLU A OE2 1 
ATOM   1145 N  N   . GLY A 1 143 ? -15.621 -35.295 23.736  1   36.08  ? 139 GLY A N   1 
ATOM   1146 C  CA  . GLY A 1 143 ? -15.356 -35.914 22.45   1   32.62  ? 139 GLY A CA  1 
ATOM   1147 C  C   . GLY A 1 143 ? -15.602 -35.019 21.238  1   30.46  ? 139 GLY A C   1 
ATOM   1148 O  O   . GLY A 1 143 ? -15.58  -35.499 20.106  1   29.68  ? 139 GLY A O   1 
ATOM   1149 N  N   . ALA A 1 144 ? -15.83  -33.723 21.481  1   28.26  ? 140 ALA A N   1 
ATOM   1150 C  CA  . ALA A 1 144 ? -15.978 -32.761 20.399  1   29.51  ? 140 ALA A CA  1 
ATOM   1151 C  C   . ALA A 1 144 ? -14.615 -32.228 19.953  1   31.02  ? 140 ALA A C   1 
ATOM   1152 O  O   . ALA A 1 144 ? -13.679 -32.163 20.737  1   30.83  ? 140 ALA A O   1 
ATOM   1153 C  CB  . ALA A 1 144 ? -16.853 -31.61  20.838  1   28.73  ? 140 ALA A CB  1 
ATOM   1154 N  N   . ILE A 1 145 ? -14.52  -31.845 18.681  1   30.06  ? 141 ILE A N   1 
ATOM   1155 C  CA  . ILE A 1 145 ? -13.354 -31.157 18.168  1   30.3   ? 141 ILE A CA  1 
ATOM   1156 C  C   . ILE A 1 145 ? -13.865 -29.946 17.395  1   28.06  ? 141 ILE A C   1 
ATOM   1157 O  O   . ILE A 1 145 ? -14.899 -30.026 16.724  1   27.91  ? 141 ILE A O   1 
ATOM   1158 C  CB  . ILE A 1 145 ? -12.44  -32.1   17.329  1   32.89  ? 141 ILE A CB  1 
ATOM   1159 C  CG1 . ILE A 1 145 ? -11.109 -31.395 16.961  1   35.68  ? 141 ILE A CG1 1 
ATOM   1160 C  CG2 . ILE A 1 145 ? -13.155 -32.632 16.092  1   34.31  ? 141 ILE A CG2 1 
ATOM   1161 C  CD1 . ILE A 1 145 ? -10.062 -32.314 16.353  1   36.16  ? 141 ILE A CD1 1 
ATOM   1162 N  N   . LYS A 1 146 ? -13.148 -28.82  17.528  1   27.79  ? 142 LYS A N   1 
ATOM   1163 C  CA  . LYS A 1 146 ? -13.604 -27.565 16.951  1   28.17  ? 142 LYS A CA  1 
ATOM   1164 C  C   . LYS A 1 146 ? -12.494 -26.756 16.285  1   31.04  ? 142 LYS A C   1 
ATOM   1165 O  O   . LYS A 1 146 ? -11.378 -26.693 16.799  1   29.74  ? 142 LYS A O   1 
ATOM   1166 C  CB  . LYS A 1 146 ? -14.249 -26.703 18.029  1   30.97  ? 142 LYS A CB  1 
ATOM   1167 C  CG  . LYS A 1 146 ? -15.238 -27.475 18.908  1   33.69  ? 142 LYS A CG  1 
ATOM   1168 C  CD  . LYS A 1 146 ? -16.15  -26.574 19.709  1   33.68  ? 142 LYS A CD  1 
ATOM   1169 C  CE  . LYS A 1 146 ? -17.056 -27.376 20.624  1   34.19  ? 142 LYS A CE  1 
ATOM   1170 N  NZ  . LYS A 1 146 ? -18.272 -26.62  21.01   1   34.15  ? 142 LYS A NZ  1 
ATOM   1171 N  N   . LEU A 1 147 ? -12.833 -26.124 15.148  1   29.85  ? 143 LEU A N   1 
ATOM   1172 C  CA  . LEU A 1 147 ? -11.933 -25.213 14.465  1   29.9   ? 143 LEU A CA  1 
ATOM   1173 C  C   . LEU A 1 147 ? -11.687 -23.993 15.347  1   32.05  ? 143 LEU A C   1 
ATOM   1174 O  O   . LEU A 1 147 ? -12.626 -23.42  15.879  1   31.88  ? 143 LEU A O   1 
ATOM   1175 C  CB  . LEU A 1 147 ? -12.509 -24.759 13.137  1   29.83  ? 143 LEU A CB  1 
ATOM   1176 C  CG  . LEU A 1 147 ? -12.351 -25.733 11.963  1   34.56  ? 143 LEU A CG  1 
ATOM   1177 C  CD1 . LEU A 1 147 ? -12.722 -27.154 12.312  1   31.24  ? 143 LEU A CD1 1 
ATOM   1178 C  CD2 . LEU A 1 147 ? -13.183 -25.275 10.792  1   38.27  ? 143 LEU A CD2 1 
ATOM   1179 N  N   . ALA A 1 148 ? -10.421 -23.603 15.491  1   31.58  ? 144 ALA A N   1 
ATOM   1180 C  CA  . ALA A 1 148 ? -10.089 -22.4   16.231  1   32.48  ? 144 ALA A CA  1 
ATOM   1181 C  C   . ALA A 1 148 ? -9.071  -21.561 15.463  1   33.81  ? 144 ALA A C   1 
ATOM   1182 O  O   . ALA A 1 148 ? -8.584  -21.966 14.4    1   30.11  ? 144 ALA A O   1 
ATOM   1183 C  CB  . ALA A 1 148 ? -9.561  -22.756 17.627  1   30.01  ? 144 ALA A CB  1 
ATOM   1184 N  N   . ASP A 1 149 ? -8.785  -20.387 16.034  1   31.12  ? 145 ASP A N   1 
ATOM   1185 C  CA  . ASP A 1 149 ? -7.804  -19.44  15.542  1   31.03  ? 145 ASP A CA  1 
ATOM   1186 C  C   . ASP A 1 149 ? -8.169  -18.961 14.141  1   28.88  ? 145 ASP A C   1 
ATOM   1187 O  O   . ASP A 1 149 ? -7.554  -19.357 13.156  1   29.26  ? 145 ASP A O   1 
ATOM   1188 C  CB  . ASP A 1 149 ? -6.39   -20.029 15.609  1   36.77  ? 145 ASP A CB  1 
ATOM   1189 C  CG  . ASP A 1 149 ? -5.283  -18.969 15.632  1   45.25  ? 145 ASP A CG  1 
ATOM   1190 O  OD1 . ASP A 1 149 ? -5.531  -17.819 15.164  1   40.09  ? 145 ASP A OD1 1 
ATOM   1191 O  OD2 . ASP A 1 149 ? -4.185  -19.27  16.155  1   53.7   ? 145 ASP A OD2 1 
ATOM   1192 N  N   . PHE A 1 150 ? -9.157  -18.068 14.083  1   28.66  ? 146 PHE A N   1 
ATOM   1193 C  CA  . PHE A 1 150 ? -9.612  -17.467 12.84   1   31.13  ? 146 PHE A CA  1 
ATOM   1194 C  C   . PHE A 1 150 ? -8.906  -16.149 12.506  1   31.4   ? 146 PHE A C   1 
ATOM   1195 O  O   . PHE A 1 150 ? -9.42   -15.334 11.741  1   25.93  ? 146 PHE A O   1 
ATOM   1196 C  CB  . PHE A 1 150 ? -11.139 -17.268 12.907  1   30.91  ? 146 PHE A CB  1 
ATOM   1197 C  CG  . PHE A 1 150 ? -11.913 -18.535 12.66   1   30.07  ? 146 PHE A CG  1 
ATOM   1198 C  CD1 . PHE A 1 150 ? -11.958 -19.536 13.61   1   30.08  ? 146 PHE A CD1 1 
ATOM   1199 C  CD2 . PHE A 1 150 ? -12.581 -18.736 11.463  1   31.52  ? 146 PHE A CD2 1 
ATOM   1200 C  CE1 . PHE A 1 150 ? -12.663 -20.715 13.371  1   27.62  ? 146 PHE A CE1 1 
ATOM   1201 C  CE2 . PHE A 1 150 ? -13.286 -19.913 11.234  1   31.28  ? 146 PHE A CE2 1 
ATOM   1202 C  CZ  . PHE A 1 150 ? -13.321 -20.889 12.196  1   28.58  ? 146 PHE A CZ  1 
ATOM   1203 N  N   . GLY A 1 151 ? -7.704  -15.95  13.065  1   34.23  ? 147 GLY A N   1 
ATOM   1204 C  CA  . GLY A 1 151 ? -6.911  -14.761 12.784  1   32.84  ? 147 GLY A CA  1 
ATOM   1205 C  C   . GLY A 1 151 ? -6.444  -14.666 11.333  1   31.86  ? 147 GLY A C   1 
ATOM   1206 O  O   . GLY A 1 151 ? -6.335  -13.57  10.79   1   31.39  ? 147 GLY A O   1 
ATOM   1207 N  N   . LEU A 1 152 ? -6.215  -15.823 10.704  1   32.18  ? 148 LEU A N   1 
ATOM   1208 C  CA  . LEU A 1 152 ? -5.801  -15.872 9.312   1   33.52  ? 148 LEU A CA  1 
ATOM   1209 C  C   . LEU A 1 152 ? -6.961  -16.012 8.324   1   29.25  ? 148 LEU A C   1 
ATOM   1210 O  O   . LEU A 1 152 ? -6.732  -16.097 7.123   1   31.48  ? 148 LEU A O   1 
ATOM   1211 C  CB  . LEU A 1 152 ? -4.825  -17.041 9.101   1   34.12  ? 148 LEU A CB  1 
ATOM   1212 C  CG  . LEU A 1 152 ? -3.398  -16.842 9.544   1   39.33  ? 148 LEU A CG  1 
ATOM   1213 C  CD1 . LEU A 1 152 ? -2.845  -15.51  9.017   1   36.74  ? 148 LEU A CD1 1 
ATOM   1214 C  CD2 . LEU A 1 152 ? -3.291  -16.989 11.054  1   43.91  ? 148 LEU A CD2 1 
ATOM   1215 N  N   . ALA A 1 153 ? -8.195  -16.004 8.832   1   28.43  ? 149 ALA A N   1 
ATOM   1216 C  CA  . ALA A 1 153 ? -9.361  -16.307 8.024   1   29.61  ? 149 ALA A CA  1 
ATOM   1217 C  C   . ALA A 1 153 ? -9.731  -15.129 7.123   1   31.72  ? 149 ALA A C   1 
ATOM   1218 O  O   . ALA A 1 153 ? -9.174  -14.037 7.262   1   27.02  ? 149 ALA A O   1 
ATOM   1219 C  CB  . ALA A 1 153 ? -10.523 -16.683 8.923   1   28.61  ? 149 ALA A CB  1 
ATOM   1220 N  N   . ARG A 1 154 ? -10.606 -15.417 6.16    1   28.92  ? 150 ARG A N   1 
ATOM   1221 C  CA  . ARG A 1 154 ? -10.996 -14.365 5.195   1   31.6   ? 150 ARG A CA  1 
ATOM   1222 C  C   . ARG A 1 154 ? -12.39  -14.587 4.611   1   31.59  ? 150 ARG A C   1 
ATOM   1223 O  O   . ARG A 1 154 ? -12.707 -15.718 4.221   1   32.65  ? 150 ARG A O   1 
ATOM   1224 C  CB  . ARG A 1 154 ? -10.059 -14.253 3.989   1   34.34  ? 150 ARG A CB  1 
ATOM   1225 C  CG  . ARG A 1 154 ? -9.727  -12.803 3.68    1   35.87  ? 150 ARG A CG  1 
ATOM   1226 C  CD  . ARG A 1 154 ? -9.7    -12.547 2.195   1   36.75  ? 150 ARG A CD  1 
ATOM   1227 N  NE  . ARG A 1 154 ? -8.604  -11.631 1.869   1   35.68  ? 150 ARG A NE  1 
ATOM   1228 C  CZ  . ARG A 1 154 ? -8.764  -10.372 1.505   1   32.33  ? 150 ARG A CZ  1 
ATOM   1229 N  NH1 . ARG A 1 154 ? -9.972  -9.845  1.471   1   35.27  ? 150 ARG A NH1 1 
ATOM   1230 N  NH2 . ARG A 1 154 ? -7.718  -9.645  1.17    1   31.3   ? 150 ARG A NH2 1 
ATOM   1231 N  N   . ALA A 1 155 ? -13.184 -13.527 4.572   1   31.76  ? 151 ALA A N   1 
ATOM   1232 C  CA  . ALA A 1 155 ? -14.478 -13.548 3.912   1   29.35  ? 151 ALA A CA  1 
ATOM   1233 C  C   . ALA A 1 155 ? -14.268 -13.436 2.407   1   27.35  ? 151 ALA A C   1 
ATOM   1234 O  O   . ALA A 1 155 ? -13.758 -12.427 1.933   1   28.79  ? 151 ALA A O   1 
ATOM   1235 C  CB  . ALA A 1 155 ? -15.34  -12.413 4.401   1   29.67  ? 151 ALA A CB  1 
ATOM   1236 N  N   . PHE A 1 156 ? -14.654 -14.474 1.662   1   26.23  ? 152 PHE A N   1 
ATOM   1237 C  CA  . PHE A 1 156 ? -14.487 -14.452 0.218   1   26.3   ? 152 PHE A CA  1 
ATOM   1238 C  C   . PHE A 1 156 ? -15.76  -14.076 -0.532  1   26.51  ? 152 PHE A C   1 
ATOM   1239 O  O   . PHE A 1 156 ? -16.857 -14.116 0.024   1   29.42  ? 152 PHE A O   1 
ATOM   1240 C  CB  . PHE A 1 156 ? -13.934 -15.775 -0.32   1   24.57  ? 152 PHE A CB  1 
ATOM   1241 C  CG  . PHE A 1 156 ? -14.748 -17.04  -0.147  1   25.8   ? 152 PHE A CG  1 
ATOM   1242 C  CD1 . PHE A 1 156 ? -14.652 -17.795 1.011   1   24.72  ? 152 PHE A CD1 1 
ATOM   1243 C  CD2 . PHE A 1 156 ? -15.558 -17.509 -1.172  1   26.37  ? 152 PHE A CD2 1 
ATOM   1244 C  CE1 . PHE A 1 156 ? -15.364 -18.974 1.146   1   24.69  ? 152 PHE A CE1 1 
ATOM   1245 C  CE2 . PHE A 1 156 ? -16.269 -18.684 -1.032  1   26.17  ? 152 PHE A CE2 1 
ATOM   1246 C  CZ  . PHE A 1 156 ? -16.161 -19.415 0.122   1   27.36  ? 152 PHE A CZ  1 
ATOM   1247 N  N   . GLY A 1 157 ? -15.565 -13.661 -1.79   1   25.99  ? 153 GLY A N   1 
ATOM   1248 C  CA  . GLY A 1 157 ? -16.637 -13.449 -2.748  1   25.01  ? 153 GLY A CA  1 
ATOM   1249 C  C   . GLY A 1 157 ? -16.646 -14.568 -3.788  1   25.02  ? 153 GLY A C   1 
ATOM   1250 O  O   . GLY A 1 157 ? -15.708 -15.358 -3.851  1   23.92  ? 153 GLY A O   1 
ATOM   1251 N  N   . VAL A 1 158 ? -17.716 -14.621 -4.591  1   25.05  ? 154 VAL A N   1 
ATOM   1252 C  CA  . VAL A 1 158 ? -17.935 -15.684 -5.559  1   24.97  ? 154 VAL A CA  1 
ATOM   1253 C  C   . VAL A 1 158 ? -18.086 -15.061 -6.944  1   24.89  ? 154 VAL A C   1 
ATOM   1254 O  O   . VAL A 1 158 ? -19.034 -14.298 -7.155  1   21.93  ? 154 VAL A O   1 
ATOM   1255 C  CB  . VAL A 1 158 ? -19.194 -16.517 -5.2    1   28.08  ? 154 VAL A CB  1 
ATOM   1256 C  CG1 . VAL A 1 158 ? -19.379 -17.667 -6.178  1   31.77  ? 154 VAL A CG1 1 
ATOM   1257 C  CG2 . VAL A 1 158 ? -19.147 -17.038 -3.76   1   29.4   ? 154 VAL A CG2 1 
ATOM   1258 N  N   . PRO A 1 159 ? -17.179 -15.325 -7.923  1   23.77  ? 155 PRO A N   1 
ATOM   1259 C  CA  . PRO A 1 159 ? -15.967 -16.116 -7.709  1   25.08  ? 155 PRO A CA  1 
ATOM   1260 C  C   . PRO A 1 159 ? -14.91  -15.425 -6.852  1   25.62  ? 155 PRO A C   1 
ATOM   1261 O  O   . PRO A 1 159 ? -14.978 -14.222 -6.619  1   26.1   ? 155 PRO A O   1 
ATOM   1262 C  CB  . PRO A 1 159 ? -15.428 -16.336 -9.138  1   24.65  ? 155 PRO A CB  1 
ATOM   1263 C  CG  . PRO A 1 159 ? -15.973 -15.235 -9.934  1   23.93  ? 155 PRO A CG  1 
ATOM   1264 C  CD  . PRO A 1 159 ? -17.29  -14.855 -9.314  1   24.5   ? 155 PRO A CD  1 
ATOM   1265 N  N   . VAL A 1 160 ? -13.939 -16.204 -6.364  1   29.24  ? 156 VAL A N   1 
ATOM   1266 C  CA  . VAL A 1 160 ? -12.876 -15.653 -5.535  1   30.61  ? 156 VAL A CA  1 
ATOM   1267 C  C   . VAL A 1 160 ? -12.059 -14.661 -6.355  1   30.37  ? 156 VAL A C   1 
ATOM   1268 O  O   . VAL A 1 160 ? -11.986 -14.77  -7.578  1   28.11  ? 156 VAL A O   1 
ATOM   1269 C  CB  . VAL A 1 160 ? -11.965 -16.73  -4.924  1   30.11  ? 156 VAL A CB  1 
ATOM   1270 C  CG1 . VAL A 1 160 ? -12.75  -17.638 -3.991  1   31.03  ? 156 VAL A CG1 1 
ATOM   1271 C  CG2 . VAL A 1 160 ? -11.239 -17.523 -6.004  1   32.91  ? 156 VAL A CG2 1 
ATOM   1272 N  N   . ARG A 1 161 ? -11.461 -13.688 -5.665  1   32.74  ? 157 ARG A N   1 
ATOM   1273 C  CA  . ARG A 1 161 ? -10.425 -12.873 -6.271  1   38.75  ? 157 ARG A CA  1 
ATOM   1274 C  C   . ARG A 1 161 ? -9.085  -13.216 -5.619  1   35.27  ? 157 ARG A C   1 
ATOM   1275 O  O   . ARG A 1 161 ? -9.003  -14.15  -4.818  1   33.11  ? 157 ARG A O   1 
ATOM   1276 C  CB  . ARG A 1 161 ? -10.798 -11.372 -6.207  1   42.28  ? 157 ARG A CB  1 
ATOM   1277 C  CG  . ARG A 1 161 ? -10.79  -10.727 -4.85   1   42.2   ? 157 ARG A CG  1 
ATOM   1278 C  CD  . ARG A 1 161 ? -10.988 -9.22   -5.017  1   47.15  ? 157 ARG A CD  1 
ATOM   1279 N  NE  . ARG A 1 161 ? -11.244 -8.544  -3.747  1   53.32  ? 157 ARG A NE  1 
ATOM   1280 C  CZ  . ARG A 1 161 ? -10.351 -8.383  -2.777  1   52.45  ? 157 ARG A CZ  1 
ATOM   1281 N  NH1 . ARG A 1 161 ? -9.093  -8.778  -2.909  1   57.14  ? 157 ARG A NH1 1 
ATOM   1282 N  NH2 . ARG A 1 161 ? -10.723 -7.784  -1.654  1   53.06  ? 157 ARG A NH2 1 
ATOM   1283 N  N   . THR A 1 162 ? -8.031  -12.484 -6.01   1   33.83  ? 158 THR A N   1 
ATOM   1284 C  CA  . THR A 1 162 ? -6.695  -12.702 -5.476  1   31.34  ? 158 THR A CA  1 
ATOM   1285 C  C   . THR A 1 162 ? -6.632  -12.247 -4.024  1   29.37  ? 158 THR A C   1 
ATOM   1286 O  O   . THR A 1 162 ? -6.947  -11.1   -3.721  1   29.31  ? 158 THR A O   1 
ATOM   1287 C  CB  . THR A 1 162 ? -5.648  -12     -6.337  1   32.38  ? 158 THR A CB  1 
ATOM   1288 O  OG1 . THR A 1 162 ? -5.685  -12.578 -7.645  1   38.97  ? 158 THR A OG1 1 
ATOM   1289 C  CG2 . THR A 1 162 ? -4.226  -12.127 -5.767  1   30.29  ? 158 THR A CG2 1 
ATOM   1290 N  N   . TYR A 1 163 ? -6.241  -13.171 -3.142  1   29.19  ? 159 TYR A N   1 
ATOM   1291 C  CA  . TYR A 1 163 ? -6.064  -12.865 -1.731  1   31.18  ? 159 TYR A CA  1 
ATOM   1292 C  C   . TYR A 1 163 ? -4.585  -12.984 -1.363  1   30.1   ? 159 TYR A C   1 
ATOM   1293 O  O   . TYR A 1 163 ? -3.742  -13.178 -2.233  1   28.55  ? 159 TYR A O   1 
ATOM   1294 C  CB  . TYR A 1 163 ? -6.953  -13.797 -0.866  1   31.68  ? 159 TYR A CB  1 
ATOM   1295 C  CG  . TYR A 1 163 ? -8.417  -13.763 -1.262  1   31.99  ? 159 TYR A CG  1 
ATOM   1296 C  CD1 . TYR A 1 163 ? -9.088  -12.558 -1.416  1   29.19  ? 159 TYR A CD1 1 
ATOM   1297 C  CD2 . TYR A 1 163 ? -9.128  -14.934 -1.476  1   32.82  ? 159 TYR A CD2 1 
ATOM   1298 C  CE1 . TYR A 1 163 ? -10.419 -12.516 -1.786  1   28.81  ? 159 TYR A CE1 1 
ATOM   1299 C  CE2 . TYR A 1 163 ? -10.469 -14.907 -1.835  1   32.89  ? 159 TYR A CE2 1 
ATOM   1300 C  CZ  . TYR A 1 163 ? -11.112 -13.694 -1.997  1   33     ? 159 TYR A CZ  1 
ATOM   1301 O  OH  . TYR A 1 163 ? -12.435 -13.655 -2.383  1   35.21  ? 159 TYR A OH  1 
HETATM 1302 N  N   . TPO A 1 164 ? -4.282  -12.854 -0.068  1   27.37  ? 160 TPO A N   1 
HETATM 1303 C  CA  . TPO A 1 164 ? -2.922  -12.912 0.43    1   29.18  ? 160 TPO A CA  1 
HETATM 1304 C  CB  . TPO A 1 164 ? -2.903  -12.764 1.961   1   28.43  ? 160 TPO A CB  1 
HETATM 1305 C  CG2 . TPO A 1 164 ? -1.506  -12.704 2.536   1   25.98  ? 160 TPO A CG2 1 
HETATM 1306 O  OG1 . TPO A 1 164 ? -3.577  -11.507 2.292   1   25.34  ? 160 TPO A OG1 1 
HETATM 1307 P  P   . TPO A 1 164 ? -4.993  -11.508 3.065   1   26.34  ? 160 TPO A P   1 
HETATM 1308 O  O1P . TPO A 1 164 ? -5.955  -12.278 2.173   1   25.11  ? 160 TPO A O1P 1 
HETATM 1309 O  O2P . TPO A 1 164 ? -5.336  -10.039 3.217   1   23.66  ? 160 TPO A O2P 1 
HETATM 1310 O  O3P . TPO A 1 164 ? -4.791  -12.196 4.411   1   26.13  ? 160 TPO A O3P 1 
HETATM 1311 C  C   . TPO A 1 164 ? -2.273  -14.219 -0.015  1   29.11  ? 160 TPO A C   1 
HETATM 1312 O  O   . TPO A 1 164 ? -2.839  -15.291 0.167   1   28.73  ? 160 TPO A O   1 
ATOM   1313 N  N   . HIS A 1 165 ? -1.078  -14.103 -0.603  1   36.91  ? 161 HIS A N   1 
ATOM   1314 C  CA  . HIS A 1 165 ? -0.291  -15.249 -1.016  1   46.12  ? 161 HIS A CA  1 
ATOM   1315 C  C   . HIS A 1 165 ? 0.514   -15.678 0.2     1   48.05  ? 161 HIS A C   1 
ATOM   1316 O  O   . HIS A 1 165 ? 0.782   -14.855 1.072   1   49.34  ? 161 HIS A O   1 
ATOM   1317 C  CB  . HIS A 1 165 ? 0.633   -14.91  -2.194  1   50.88  ? 161 HIS A CB  1 
ATOM   1318 C  CG  . HIS A 1 165 ? 1.469   -16.073 -2.635  1   71.16  ? 161 HIS A CG  1 
ATOM   1319 N  ND1 . HIS A 1 165 ? 2.83    -15.942 -2.857  1   85.79  ? 161 HIS A ND1 1 
ATOM   1320 C  CD2 . HIS A 1 165 ? 1.109   -17.352 -2.892  1   68.57  ? 161 HIS A CD2 1 
ATOM   1321 C  CE1 . HIS A 1 165 ? 3.262   -17.142 -3.225  1   79.84  ? 161 HIS A CE1 1 
ATOM   1322 N  NE2 . HIS A 1 165 ? 2.255   -18.025 -3.245  1   72.72  ? 161 HIS A NE2 1 
ATOM   1323 N  N   . GLU A 1 166 ? 0.907   -16.955 0.252   1   58.22  ? 162 GLU A N   1 
ATOM   1324 C  CA  . GLU A 1 166 ? 1.686   -17.46  1.375   1   70.5   ? 162 GLU A CA  1 
ATOM   1325 C  C   . GLU A 1 166 ? 0.826   -17.277 2.627   1   63.04  ? 162 GLU A C   1 
ATOM   1326 O  O   . GLU A 1 166 ? 0.958   -16.32  3.399   1   50.02  ? 162 GLU A O   1 
ATOM   1327 C  CB  . GLU A 1 166 ? 3.083   -16.791 1.478   1   78.45  ? 162 GLU A CB  1 
ATOM   1328 C  CG  . GLU A 1 166 ? 4.08    -17.336 0.463   1   83.61  ? 162 GLU A CG  1 
ATOM   1329 C  CD  . GLU A 1 166 ? 5.376   -16.55  0.317   1   81.7   ? 162 GLU A CD  1 
ATOM   1330 O  OE1 . GLU A 1 166 ? 5.885   -16.023 1.333   1   79.85  ? 162 GLU A OE1 1 
ATOM   1331 O  OE2 . GLU A 1 166 ? 5.9     -16.488 -0.817  1   79.93  ? 162 GLU A OE2 1 
ATOM   1332 N  N   . VAL A 1 167 ? -0.132  -18.198 2.72    1   52.78  ? 163 VAL A N   1 
ATOM   1333 C  CA  . VAL A 1 167 ? -1.035  -18.35  3.845   1   44.16  ? 163 VAL A CA  1 
ATOM   1334 C  C   . VAL A 1 167 ? -0.945  -19.845 4.117   1   36.78  ? 163 VAL A C   1 
ATOM   1335 O  O   . VAL A 1 167 ? -0.487  -20.571 3.241   1   35.37  ? 163 VAL A O   1 
ATOM   1336 C  CB  . VAL A 1 167 ? -2.459  -17.912 3.482   1   41.99  ? 163 VAL A CB  1 
ATOM   1337 C  CG1 . VAL A 1 167 ? -2.551  -16.4   3.373   1   43.12  ? 163 VAL A CG1 1 
ATOM   1338 C  CG2 . VAL A 1 167 ? -2.936  -18.574 2.189   1   36.16  ? 163 VAL A CG2 1 
ATOM   1339 N  N   . VAL A 1 168 ? -1.4    -20.276 5.294   1   31.25  ? 164 VAL A N   1 
ATOM   1340 C  CA  . VAL A 1 168 ? -1.345  -21.658 5.741   1   28.53  ? 164 VAL A CA  1 
ATOM   1341 C  C   . VAL A 1 168 ? 0.092   -21.981 6.159   1   32.15  ? 164 VAL A C   1 
ATOM   1342 O  O   . VAL A 1 168 ? 1.044   -21.731 5.418   1   29.17  ? 164 VAL A O   1 
ATOM   1343 C  CB  . VAL A 1 168 ? -1.885  -22.702 4.717   1   27.55  ? 164 VAL A CB  1 
ATOM   1344 C  CG1 . VAL A 1 168 ? -2.134  -24.042 5.397   1   27.79  ? 164 VAL A CG1 1 
ATOM   1345 C  CG2 . VAL A 1 168 ? -3.147  -22.233 4.003   1   27.09  ? 164 VAL A CG2 1 
ATOM   1346 N  N   . THR A 1 169 ? 0.237   -22.536 7.369   1   30.78  ? 165 THR A N   1 
ATOM   1347 C  CA  . THR A 1 169 ? 1.494   -23.098 7.813   1   28.33  ? 165 THR A CA  1 
ATOM   1348 C  C   . THR A 1 169 ? 1.979   -24.093 6.76    1   30.23  ? 165 THR A C   1 
ATOM   1349 O  O   . THR A 1 169 ? 1.197   -24.888 6.235   1   27.27  ? 165 THR A O   1 
ATOM   1350 C  CB  . THR A 1 169 ? 1.315   -23.73  9.186   1   27.97  ? 165 THR A CB  1 
ATOM   1351 O  OG1 . THR A 1 169 ? 0.751   -22.737 10.019  1   26.04  ? 165 THR A OG1 1 
ATOM   1352 C  CG2 . THR A 1 169 ? 2.632   -24.251 9.776   1   25.06  ? 165 THR A CG2 1 
ATOM   1353 N  N   . LEU A 1 170 ? 3.289   -24.032 6.483   1   29.54  ? 166 LEU A N   1 
ATOM   1354 C  CA  . LEU A 1 170 ? 3.883   -24.66  5.319   1   29.66  ? 166 LEU A CA  1 
ATOM   1355 C  C   . LEU A 1 170 ? 3.501   -26.13  5.166   1   28.57  ? 166 LEU A C   1 
ATOM   1356 O  O   . LEU A 1 170 ? 3.09    -26.554 4.087   1   27.45  ? 166 LEU A O   1 
ATOM   1357 C  CB  . LEU A 1 170 ? 5.418   -24.481 5.43    1   29.24  ? 166 LEU A CB  1 
ATOM   1358 C  CG  . LEU A 1 170 ? 6.251   -25.052 4.309   1   29.28  ? 166 LEU A CG  1 
ATOM   1359 C  CD1 . LEU A 1 170 ? 5.951   -24.326 3.001   1   31.81  ? 166 LEU A CD1 1 
ATOM   1360 C  CD2 . LEU A 1 170 ? 7.74    -24.972 4.652   1   27.3   ? 166 LEU A CD2 1 
ATOM   1361 N  N   . TRP A 1 171 ? 3.622   -26.908 6.251   1   28.05  ? 167 TRP A N   1 
ATOM   1362 C  CA  . TRP A 1 171 ? 3.372   -28.341 6.176   1   26.57  ? 167 TRP A CA  1 
ATOM   1363 C  C   . TRP A 1 171 ? 1.962   -28.688 5.703   1   26.34  ? 167 TRP A C   1 
ATOM   1364 O  O   . TRP A 1 171 ? 1.744   -29.8   5.233   1   26.63  ? 167 TRP A O   1 
ATOM   1365 C  CB  . TRP A 1 171 ? 3.616   -29.028 7.518   1   24.06  ? 167 TRP A CB  1 
ATOM   1366 C  CG  . TRP A 1 171 ? 5.028   -29.016 7.969   1   24.73  ? 167 TRP A CG  1 
ATOM   1367 C  CD1 . TRP A 1 171 ? 6.108   -28.511 7.299   1   26.93  ? 167 TRP A CD1 1 
ATOM   1368 C  CD2 . TRP A 1 171 ? 5.518   -29.495 9.219   1   24.3   ? 167 TRP A CD2 1 
ATOM   1369 N  NE1 . TRP A 1 171 ? 7.241   -28.651 8.057   1   26.89  ? 167 TRP A NE1 1 
ATOM   1370 C  CE2 . TRP A 1 171 ? 6.908   -29.253 9.245   1   28.1   ? 167 TRP A CE2 1 
ATOM   1371 C  CE3 . TRP A 1 171 ? 4.915   -30.084 10.331  1   26.27  ? 167 TRP A CE3 1 
ATOM   1372 C  CZ2 . TRP A 1 171 ? 7.71    -29.62  10.33   1   29.84  ? 167 TRP A CZ2 1 
ATOM   1373 C  CZ3 . TRP A 1 171 ? 5.701   -30.451 11.406  1   27.3   ? 167 TRP A CZ3 1 
ATOM   1374 C  CH2 . TRP A 1 171 ? 7.083   -30.21  11.408  1   28.77  ? 167 TRP A CH2 1 
ATOM   1375 N  N   . TYR A 1 172 ? 1.029   -27.734 5.846   1   24.28  ? 168 TYR A N   1 
ATOM   1376 C  CA  . TYR A 1 172 ? -0.384  -27.952 5.577   1   27.12  ? 168 TYR A CA  1 
ATOM   1377 C  C   . TYR A 1 172 ? -0.851  -27.16  4.351   1   27.89  ? 168 TYR A C   1 
ATOM   1378 O  O   . TYR A 1 172 ? -2.042  -27.084 4.078   1   25.9   ? 168 TYR A O   1 
ATOM   1379 C  CB  . TYR A 1 172 ? -1.195  -27.598 6.864   1   26.02  ? 168 TYR A CB  1 
ATOM   1380 C  CG  . TYR A 1 172 ? -0.716  -28.407 8.058   1   25.33  ? 168 TYR A CG  1 
ATOM   1381 C  CD1 . TYR A 1 172 ? -1.161  -29.707 8.266   1   25.4   ? 168 TYR A CD1 1 
ATOM   1382 C  CD2 . TYR A 1 172 ? 0.269   -27.913 8.911   1   26.18  ? 168 TYR A CD2 1 
ATOM   1383 C  CE1 . TYR A 1 172 ? -0.699  -30.468 9.341   1   26.18  ? 168 TYR A CE1 1 
ATOM   1384 C  CE2 . TYR A 1 172 ? 0.757   -28.671 9.974   1   24.8   ? 168 TYR A CE2 1 
ATOM   1385 C  CZ  . TYR A 1 172 ? 0.271   -29.951 10.186  1   25.34  ? 168 TYR A CZ  1 
ATOM   1386 O  OH  . TYR A 1 172 ? 0.743   -30.687 11.235  1   21.99  ? 168 TYR A OH  1 
ATOM   1387 N  N   . ARG A 1 173 ? 0.105   -26.59  3.605   1   27.27  ? 169 ARG A N   1 
ATOM   1388 C  CA  . ARG A 1 173 ? -0.187  -25.685 2.503   1   29.04  ? 169 ARG A CA  1 
ATOM   1389 C  C   . ARG A 1 173 ? -0.368  -26.397 1.161   1   28.05  ? 169 ARG A C   1 
ATOM   1390 O  O   . ARG A 1 173 ? 0.458   -27.218 0.767   1   27.8   ? 169 ARG A O   1 
ATOM   1391 C  CB  . ARG A 1 173 ? 0.946   -24.67  2.402   1   28.52  ? 169 ARG A CB  1 
ATOM   1392 C  CG  . ARG A 1 173 ? 0.675   -23.506 1.458   1   29.11  ? 169 ARG A CG  1 
ATOM   1393 C  CD  . ARG A 1 173 ? 1.864   -22.567 1.397   1   28.53  ? 169 ARG A CD  1 
ATOM   1394 N  NE  . ARG A 1 173 ? 2.171   -21.99  2.707   1   27.81  ? 169 ARG A NE  1 
ATOM   1395 C  CZ  . ARG A 1 173 ? 3.286   -21.334 2.987   1   28.38  ? 169 ARG A CZ  1 
ATOM   1396 N  NH1 . ARG A 1 173 ? 4.182   -21.07  2.054   1   27.38  ? 169 ARG A NH1 1 
ATOM   1397 N  NH2 . ARG A 1 173 ? 3.518   -20.951 4.236   1   29.74  ? 169 ARG A NH2 1 
ATOM   1398 N  N   . ALA A 1 174 ? -1.466  -26.073 0.471   1   27.28  ? 170 ALA A N   1 
ATOM   1399 C  CA  . ALA A 1 174 ? -1.823  -26.718 -0.783  1   29.59  ? 170 ALA A CA  1 
ATOM   1400 C  C   . ALA A 1 174 ? -0.87   -26.382 -1.932  1   29.01  ? 170 ALA A C   1 
ATOM   1401 O  O   . ALA A 1 174 ? -0.257  -25.319 -1.955  1   28.74  ? 170 ALA A O   1 
ATOM   1402 C  CB  . ALA A 1 174 ? -3.239  -26.317 -1.163  1   32.5   ? 170 ALA A CB  1 
ATOM   1403 N  N   . PRO A 1 175 ? -0.74   -27.267 -2.942  1   28.44  ? 171 PRO A N   1 
ATOM   1404 C  CA  . PRO A 1 175 ? 0.212   -27.053 -4.031  1   28.73  ? 171 PRO A CA  1 
ATOM   1405 C  C   . PRO A 1 175 ? -0.078  -25.813 -4.872  1   27.49  ? 171 PRO A C   1 
ATOM   1406 O  O   . PRO A 1 175 ? 0.853   -25.192 -5.384  1   26.5   ? 171 PRO A O   1 
ATOM   1407 C  CB  . PRO A 1 175 ? 0.116   -28.346 -4.852  1   28.59  ? 171 PRO A CB  1 
ATOM   1408 C  CG  . PRO A 1 175 ? -1.182  -28.945 -4.483  1   28.52  ? 171 PRO A CG  1 
ATOM   1409 C  CD  . PRO A 1 175 ? -1.487  -28.525 -3.079  1   29.55  ? 171 PRO A CD  1 
ATOM   1410 N  N   . GLU A 1 176 ? -1.363  -25.452 -4.997  1   27.24  ? 172 GLU A N   1 
ATOM   1411 C  CA  . GLU A 1 176 ? -1.741  -24.292 -5.79   1   27.15  ? 172 GLU A CA  1 
ATOM   1412 C  C   . GLU A 1 176 ? -1.195  -23.016 -5.149  1   29.53  ? 172 GLU A C   1 
ATOM   1413 O  O   . GLU A 1 176 ? -0.805  -22.086 -5.862  1   28.61  ? 172 GLU A O   1 
ATOM   1414 C  CB  . GLU A 1 176 ? -3.272  -24.188 -6.019  1   27.44  ? 172 GLU A CB  1 
ATOM   1415 C  CG  . GLU A 1 176 ? -4.154  -24.168 -4.772  1   28.06  ? 172 GLU A CG  1 
ATOM   1416 C  CD  . GLU A 1 176 ? -4.702  -25.504 -4.3    1   27.1   ? 172 GLU A CD  1 
ATOM   1417 O  OE1 . GLU A 1 176 ? -3.98   -26.512 -4.444  1   23.66  ? 172 GLU A OE1 1 
ATOM   1418 O  OE2 . GLU A 1 176 ? -5.848  -25.538 -3.78   1   27.62  ? 172 GLU A OE2 1 
ATOM   1419 N  N   . ILE A 1 177 ? -1.144  -22.98  -3.808  1   27.44  ? 173 ILE A N   1 
ATOM   1420 C  CA  . ILE A 1 177 ? -0.545  -21.845 -3.118  1   27     ? 173 ILE A CA  1 
ATOM   1421 C  C   . ILE A 1 177 ? 0.96    -21.866 -3.359  1   25.03  ? 173 ILE A C   1 
ATOM   1422 O  O   . ILE A 1 177 ? 1.546   -20.852 -3.73   1   24.92  ? 173 ILE A O   1 
ATOM   1423 C  CB  . ILE A 1 177 ? -0.877  -21.808 -1.605  1   28.32  ? 173 ILE A CB  1 
ATOM   1424 C  CG1 . ILE A 1 177 ? -2.405  -21.792 -1.359  1   30.51  ? 173 ILE A CG1 1 
ATOM   1425 C  CG2 . ILE A 1 177 ? -0.203  -20.615 -0.936  1   27.54  ? 173 ILE A CG2 1 
ATOM   1426 C  CD1 . ILE A 1 177 ? -2.822  -21.874 0.11    1   31.23  ? 173 ILE A CD1 1 
ATOM   1427 N  N   . LEU A 1 178 ? 1.573   -23.043 -3.188  1   25.32  ? 174 LEU A N   1 
ATOM   1428 C  CA  . LEU A 1 178 ? 3.009   -23.197 -3.366  1   26.58  ? 174 LEU A CA  1 
ATOM   1429 C  C   . LEU A 1 178 ? 3.477   -22.831 -4.773  1   25.88  ? 174 LEU A C   1 
ATOM   1430 O  O   . LEU A 1 178 ? 4.578   -22.316 -4.924  1   27.35  ? 174 LEU A O   1 
ATOM   1431 C  CB  . LEU A 1 178 ? 3.421   -24.641 -3.027  1   28.53  ? 174 LEU A CB  1 
ATOM   1432 C  CG  . LEU A 1 178 ? 3.402   -24.99  -1.53   1   27.64  ? 174 LEU A CG  1 
ATOM   1433 C  CD1 . LEU A 1 178 ? 3.507   -26.48  -1.308  1   27.02  ? 174 LEU A CD1 1 
ATOM   1434 C  CD2 . LEU A 1 178 ? 4.522   -24.279 -0.8    1   27.17  ? 174 LEU A CD2 1 
ATOM   1435 N  N   . LEU A 1 179 ? 2.643   -23.087 -5.793  1   25.07  ? 175 LEU A N   1 
ATOM   1436 C  CA  . LEU A 1 179 ? 2.969   -22.725 -7.168  1   27.04  ? 175 LEU A CA  1 
ATOM   1437 C  C   . LEU A 1 179 ? 2.561   -21.3   -7.551  1   26.07  ? 175 LEU A C   1 
ATOM   1438 O  O   . LEU A 1 179 ? 2.578   -20.936 -8.728  1   29.4   ? 175 LEU A O   1 
ATOM   1439 C  CB  . LEU A 1 179 ? 2.293   -23.733 -8.125  1   26.73  ? 175 LEU A CB  1 
ATOM   1440 C  CG  . LEU A 1 179 ? 2.804   -25.157 -8.034  1   27.14  ? 175 LEU A CG  1 
ATOM   1441 C  CD1 . LEU A 1 179 ? 1.975   -26.068 -8.903  1   27.38  ? 175 LEU A CD1 1 
ATOM   1442 C  CD2 . LEU A 1 179 ? 4.306   -25.229 -8.407  1   25.81  ? 175 LEU A CD2 1 
ATOM   1443 N  N   . GLY A 1 180 ? 2.161   -20.505 -6.557  1   25.93  ? 176 GLY A N   1 
ATOM   1444 C  CA  . GLY A 1 180 ? 1.884   -19.093 -6.756  1   26.37  ? 176 GLY A CA  1 
ATOM   1445 C  C   . GLY A 1 180 ? 0.63    -18.76  -7.567  1   27.82  ? 176 GLY A C   1 
ATOM   1446 O  O   . GLY A 1 180 ? 0.58    -17.71  -8.201  1   29.37  ? 176 GLY A O   1 
ATOM   1447 N  N   A CYS A 1 181 ? -0.369  -19.654 -7.571  0.5 26.98  ? 177 CYS A N   1 
ATOM   1448 N  N   B CYS A 1 181 ? -0.386  -19.631 -7.469  0.5 27.47  ? 177 CYS A N   1 
ATOM   1449 C  CA  A CYS A 1 181 ? -1.528  -19.477 -8.434  0.5 26.79  ? 177 CYS A CA  1 
ATOM   1450 C  CA  B CYS A 1 181 ? -1.679  -19.456 -8.117  0.5 27.6   ? 177 CYS A CA  1 
ATOM   1451 C  C   A CYS A 1 181 ? -2.255  -18.189 -8.039  0.5 27.71  ? 177 CYS A C   1 
ATOM   1452 C  C   B CYS A 1 181 ? -2.19   -18.031 -7.984  0.5 27.9   ? 177 CYS A C   1 
ATOM   1453 O  O   A CYS A 1 181 ? -2.243  -17.789 -6.879  0.5 28.67  ? 177 CYS A O   1 
ATOM   1454 O  O   B CYS A 1 181 ? -2.048  -17.425 -6.924  0.5 27.83  ? 177 CYS A O   1 
ATOM   1455 C  CB  A CYS A 1 181 ? -2.442  -20.712 -8.417  0.5 25.05  ? 177 CYS A CB  1 
ATOM   1456 C  CB  B CYS A 1 181 ? -2.703  -20.425 -7.524  0.5 26.43  ? 177 CYS A CB  1 
ATOM   1457 S  SG  A CYS A 1 181 ? -1.876  -22.095 -9.485  0.5 20.56  ? 177 CYS A SG  1 
ATOM   1458 S  SG  B CYS A 1 181 ? -2.974  -20.222 -5.732  0.5 23.9   ? 177 CYS A SG  1 
ATOM   1459 N  N   . LYS A 1 182 ? -2.818  -17.514 -9.045  1   28.64  ? 178 LYS A N   1 
ATOM   1460 C  CA  . LYS A 1 182 ? -3.466  -16.218 -8.915  1   32.18  ? 178 LYS A CA  1 
ATOM   1461 C  C   . LYS A 1 182 ? -4.672  -16.309 -7.977  1   29.46  ? 178 LYS A C   1 
ATOM   1462 O  O   . LYS A 1 182 ? -4.952  -15.391 -7.213  1   24.85  ? 178 LYS A O   1 
ATOM   1463 C  CB  . LYS A 1 182 ? -3.9    -15.725 -10.31  1   38.63  ? 178 LYS A CB  1 
ATOM   1464 C  CG  . LYS A 1 182 ? -4.42   -14.303 -10.348 1   46.55  ? 178 LYS A CG  1 
ATOM   1465 C  CD  . LYS A 1 182 ? -4.98   -13.889 -11.726 1   54.75  ? 178 LYS A CD  1 
ATOM   1466 C  CE  . LYS A 1 182 ? -5.368  -12.412 -11.735 1   58.79  ? 178 LYS A CE  1 
ATOM   1467 N  NZ  . LYS A 1 182 ? -5.755  -11.933 -13.088 1   61.23  ? 178 LYS A NZ  1 
ATOM   1468 N  N   . TYR A 1 183 ? -5.392  -17.433 -8.07   1   27.44  ? 179 TYR A N   1 
ATOM   1469 C  CA  . TYR A 1 183 ? -6.595  -17.665 -7.298  1   28.91  ? 179 TYR A CA  1 
ATOM   1470 C  C   . TYR A 1 183 ? -6.449  -18.96  -6.51   1   30.25  ? 179 TYR A C   1 
ATOM   1471 O  O   . TYR A 1 183 ? -5.891  -19.927 -7.021  1   31.48  ? 179 TYR A O   1 
ATOM   1472 C  CB  . TYR A 1 183 ? -7.817  -17.788 -8.217  1   30.35  ? 179 TYR A CB  1 
ATOM   1473 C  CG  . TYR A 1 183 ? -8.098  -16.598 -9.119  1   32.02  ? 179 TYR A CG  1 
ATOM   1474 C  CD1 . TYR A 1 183 ? -8.291  -15.322 -8.589  1   32.51  ? 179 TYR A CD1 1 
ATOM   1475 C  CD2 . TYR A 1 183 ? -8.208  -16.753 -10.495 1   31.94  ? 179 TYR A CD2 1 
ATOM   1476 C  CE1 . TYR A 1 183 ? -8.539  -14.229 -9.412  1   31.92  ? 179 TYR A CE1 1 
ATOM   1477 C  CE2 . TYR A 1 183 ? -8.485  -15.671 -11.325 1   33.37  ? 179 TYR A CE2 1 
ATOM   1478 C  CZ  . TYR A 1 183 ? -8.657  -14.411 -10.777 1   34.78  ? 179 TYR A CZ  1 
ATOM   1479 O  OH  . TYR A 1 183 ? -8.916  -13.33  -11.582 1   35.61  ? 179 TYR A OH  1 
ATOM   1480 N  N   . TYR A 1 184 ? -6.935  -18.947 -5.265  1   29.78  ? 180 TYR A N   1 
ATOM   1481 C  CA  . TYR A 1 184 ? -7.218  -20.169 -4.531  1   29.79  ? 180 TYR A CA  1 
ATOM   1482 C  C   . TYR A 1 184 ? -8.571  -20.034 -3.831  1   28.76  ? 180 TYR A C   1 
ATOM   1483 O  O   . TYR A 1 184 ? -9.094  -18.933 -3.683  1   25.94  ? 180 TYR A O   1 
ATOM   1484 C  CB  . TYR A 1 184 ? -6.105  -20.516 -3.536  1   28.26  ? 180 TYR A CB  1 
ATOM   1485 C  CG  . TYR A 1 184 ? -5.868  -19.454 -2.491  1   29.3   ? 180 TYR A CG  1 
ATOM   1486 C  CD1 . TYR A 1 184 ? -6.715  -19.325 -1.392  1   28.49  ? 180 TYR A CD1 1 
ATOM   1487 C  CD2 . TYR A 1 184 ? -4.796  -18.582 -2.592  1   28.26  ? 180 TYR A CD2 1 
ATOM   1488 C  CE1 . TYR A 1 184 ? -6.497  -18.349 -0.426  1   29.14  ? 180 TYR A CE1 1 
ATOM   1489 C  CE2 . TYR A 1 184 ? -4.569  -17.598 -1.63   1   29.9   ? 180 TYR A CE2 1 
ATOM   1490 C  CZ  . TYR A 1 184 ? -5.426  -17.479 -0.554  1   29.36  ? 180 TYR A CZ  1 
ATOM   1491 O  OH  . TYR A 1 184 ? -5.206  -16.498 0.379   1   27.12  ? 180 TYR A OH  1 
ATOM   1492 N  N   . SER A 1 185 ? -9.12   -21.174 -3.401  1   27.29  ? 181 SER A N   1 
ATOM   1493 C  CA  . SER A 1 185 ? -10.493 -21.225 -2.932  1   30.65  ? 181 SER A CA  1 
ATOM   1494 C  C   . SER A 1 185 ? -10.625 -22.224 -1.787  1   28.48  ? 181 SER A C   1 
ATOM   1495 O  O   . SER A 1 185 ? -9.641  -22.567 -1.139  1   28.29  ? 181 SER A O   1 
ATOM   1496 C  CB  . SER A 1 185 ? -11.429 -21.564 -4.102  1   30.79  ? 181 SER A CB  1 
ATOM   1497 O  OG  . SER A 1 185 ? -12.805 -21.433 -3.771  1   28.63  ? 181 SER A OG  1 
ATOM   1498 N  N   . THR A 1 186 ? -11.852 -22.702 -1.578  1   27.04  ? 182 THR A N   1 
ATOM   1499 C  CA  . THR A 1 186 ? -12.175 -23.598 -0.48   1   28.15  ? 182 THR A CA  1 
ATOM   1500 C  C   . THR A 1 186 ? -11.29  -24.837 -0.424  1   28.21  ? 182 THR A C   1 
ATOM   1501 O  O   . THR A 1 186 ? -11.061 -25.382 0.65    1   30.11  ? 182 THR A O   1 
ATOM   1502 C  CB  . THR A 1 186 ? -13.654 -23.991 -0.584  1   27.35  ? 182 THR A CB  1 
ATOM   1503 O  OG1 . THR A 1 186 ? -13.905 -24.559 -1.904  1   23.98  ? 182 THR A OG1 1 
ATOM   1504 C  CG2 . THR A 1 186 ? -14.567 -22.795 -0.318  1   27.99  ? 182 THR A CG2 1 
ATOM   1505 N  N   . ALA A 1 187 ? -10.806 -25.274 -1.588  1   28.99  ? 183 ALA A N   1 
ATOM   1506 C  CA  . ALA A 1 187 ? -9.976  -26.462 -1.701  1   28.82  ? 183 ALA A CA  1 
ATOM   1507 C  C   . ALA A 1 187 ? -8.682  -26.433 -0.885  1   29.73  ? 183 ALA A C   1 
ATOM   1508 O  O   . ALA A 1 187 ? -8.183  -27.493 -0.52   1   29.4   ? 183 ALA A O   1 
ATOM   1509 C  CB  . ALA A 1 187 ? -9.652  -26.71  -3.173  1   27.55  ? 183 ALA A CB  1 
ATOM   1510 N  N   . VAL A 1 188 ? -8.146  -25.24  -0.576  1   28.86  ? 184 VAL A N   1 
ATOM   1511 C  CA  . VAL A 1 188 ? -6.935  -25.161 0.232   1   29.33  ? 184 VAL A CA  1 
ATOM   1512 C  C   . VAL A 1 188 ? -7.204  -25.629 1.667   1   29.32  ? 184 VAL A C   1 
ATOM   1513 O  O   . VAL A 1 188 ? -6.325  -26.186 2.316   1   32.68  ? 184 VAL A O   1 
ATOM   1514 C  CB  . VAL A 1 188 ? -6.28   -23.753 0.241   1   29.52  ? 184 VAL A CB  1 
ATOM   1515 C  CG1 . VAL A 1 188 ? -6.268  -23.127 -1.14   1   28.36  ? 184 VAL A CG1 1 
ATOM   1516 C  CG2 . VAL A 1 188 ? -6.946  -22.815 1.238   1   29.6   ? 184 VAL A CG2 1 
ATOM   1517 N  N   . ASP A 1 189 ? -8.425  -25.414 2.17    1   30.02  ? 185 ASP A N   1 
ATOM   1518 C  CA  . ASP A 1 189 ? -8.769  -25.885 3.505   1   29.15  ? 185 ASP A CA  1 
ATOM   1519 C  C   . ASP A 1 189 ? -8.914  -27.406 3.505   1   27.23  ? 185 ASP A C   1 
ATOM   1520 O  O   . ASP A 1 189 ? -8.532  -28.061 4.468   1   26.32  ? 185 ASP A O   1 
ATOM   1521 C  CB  . ASP A 1 189 ? -10.036 -25.204 4.055   1   28.6   ? 185 ASP A CB  1 
ATOM   1522 C  CG  . ASP A 1 189 ? -9.874  -23.755 4.52    1   31.1   ? 185 ASP A CG  1 
ATOM   1523 O  OD1 . ASP A 1 189 ? -8.737  -23.363 4.878   1   27.67  ? 185 ASP A OD1 1 
ATOM   1524 O  OD2 . ASP A 1 189 ? -10.891 -22.99  4.481   1   32.68  ? 185 ASP A OD2 1 
ATOM   1525 N  N   . ILE A 1 190 ? -9.427  -27.969 2.407   1   26.02  ? 186 ILE A N   1 
ATOM   1526 C  CA  . ILE A 1 190 ? -9.532  -29.417 2.301   1   29.04  ? 186 ILE A CA  1 
ATOM   1527 C  C   . ILE A 1 190 ? -8.146  -30.069 2.287   1   28.88  ? 186 ILE A C   1 
ATOM   1528 O  O   . ILE A 1 190 ? -7.919  -31.086 2.952   1   24.32  ? 186 ILE A O   1 
ATOM   1529 C  CB  . ILE A 1 190 ? -10.408 -29.817 1.096   1   29.72  ? 186 ILE A CB  1 
ATOM   1530 C  CG1 . ILE A 1 190 ? -11.904 -29.49  1.398   1   31.18  ? 186 ILE A CG1 1 
ATOM   1531 C  CG2 . ILE A 1 190 ? -10.228 -31.286 0.724   1   30.24  ? 186 ILE A CG2 1 
ATOM   1532 C  CD1 . ILE A 1 190 ? -12.553 -30.374 2.479   1   31.85  ? 186 ILE A CD1 1 
ATOM   1533 N  N   . TRP A 1 191 ? -7.207  -29.455 1.562   1   28.9   ? 187 TRP A N   1 
ATOM   1534 C  CA  . TRP A 1 191 ? -5.854  -29.981 1.527   1   28.83  ? 187 TRP A CA  1 
ATOM   1535 C  C   . TRP A 1 191 ? -5.303  -30.127 2.944   1   28.53  ? 187 TRP A C   1 
ATOM   1536 O  O   . TRP A 1 191 ? -4.804  -31.186 3.32    1   31.25  ? 187 TRP A O   1 
ATOM   1537 C  CB  . TRP A 1 191 ? -4.951  -29.122 0.641   1   27.71  ? 187 TRP A CB  1 
ATOM   1538 C  CG  . TRP A 1 191 ? -3.554  -29.65  0.562   1   28.87  ? 187 TRP A CG  1 
ATOM   1539 C  CD1 . TRP A 1 191 ? -2.551  -29.428 1.451   1   26.52  ? 187 TRP A CD1 1 
ATOM   1540 C  CD2 . TRP A 1 191 ? -3.02   -30.532 -0.435  1   26.47  ? 187 TRP A CD2 1 
ATOM   1541 N  NE1 . TRP A 1 191 ? -1.425  -30.105 1.066   1   27.36  ? 187 TRP A NE1 1 
ATOM   1542 C  CE2 . TRP A 1 191 ? -1.68   -30.778 -0.096  1   26.01  ? 187 TRP A CE2 1 
ATOM   1543 C  CE3 . TRP A 1 191 ? -3.539  -31.115 -1.596  1   28.28  ? 187 TRP A CE3 1 
ATOM   1544 C  CZ2 . TRP A 1 191 ? -0.853  -31.588 -0.867  1   26.29  ? 187 TRP A CZ2 1 
ATOM   1545 C  CZ3 . TRP A 1 191 ? -2.713  -31.911 -2.371  1   27.67  ? 187 TRP A CZ3 1 
ATOM   1546 C  CH2 . TRP A 1 191 ? -1.393  -32.152 -1.999  1   25.67  ? 187 TRP A CH2 1 
ATOM   1547 N  N   . SER A 1 192 ? -5.417  -29.059 3.736   1   31.43  ? 188 SER A N   1 
ATOM   1548 C  CA  . SER A 1 192 ? -4.948  -29.08  5.116   1   31.14  ? 188 SER A CA  1 
ATOM   1549 C  C   . SER A 1 192 ? -5.558  -30.233 5.918   1   29.2   ? 188 SER A C   1 
ATOM   1550 O  O   . SER A 1 192 ? -4.846  -30.961 6.592   1   25.94  ? 188 SER A O   1 
ATOM   1551 C  CB  . SER A 1 192 ? -5.234  -27.738 5.791   1   31.5   ? 188 SER A CB  1 
ATOM   1552 O  OG  . SER A 1 192 ? -4.649  -26.656 5.083   1   30.17  ? 188 SER A OG  1 
ATOM   1553 N  N   . LEU A 1 193 ? -6.881  -30.4   5.822   1   30.53  ? 189 LEU A N   1 
ATOM   1554 C  CA  . LEU A 1 193 ? -7.577  -31.462 6.53    1   31.4   ? 189 LEU A CA  1 
ATOM   1555 C  C   . LEU A 1 193 ? -7.142  -32.855 6.08    1   28.96  ? 189 LEU A C   1 
ATOM   1556 O  O   . LEU A 1 193 ? -7.116  -33.779 6.892   1   27.68  ? 189 LEU A O   1 
ATOM   1557 C  CB  . LEU A 1 193 ? -9.1    -31.33  6.344   1   31.09  ? 189 LEU A CB  1 
ATOM   1558 C  CG  . LEU A 1 193 ? -9.824  -30.382 7.27    1   35.42  ? 189 LEU A CG  1 
ATOM   1559 C  CD1 . LEU A 1 193 ? -11.34  -30.591 7.186   1   35.97  ? 189 LEU A CD1 1 
ATOM   1560 C  CD2 . LEU A 1 193 ? -9.386  -30.557 8.727   1   37.03  ? 189 LEU A CD2 1 
ATOM   1561 N  N   . GLY A 1 194 ? -6.851  -33.002 4.782   1   28.44  ? 190 GLY A N   1 
ATOM   1562 C  CA  . GLY A 1 194 ? -6.227  -34.211 4.271   1   29.2   ? 190 GLY A CA  1 
ATOM   1563 C  C   . GLY A 1 194 ? -4.91   -34.527 4.98    1   28.21  ? 190 GLY A C   1 
ATOM   1564 O  O   . GLY A 1 194 ? -4.699  -35.646 5.456   1   28.65  ? 190 GLY A O   1 
ATOM   1565 N  N   . CYS A 1 195 ? -4.043  -33.514 5.078   1   27.01  ? 191 CYS A N   1 
ATOM   1566 C  CA  . CYS A 1 195 ? -2.782  -33.659 5.79    1   27.65  ? 191 CYS A CA  1 
ATOM   1567 C  C   . CYS A 1 195 ? -3.042  -34.045 7.241   1   28.14  ? 191 CYS A C   1 
ATOM   1568 O  O   . CYS A 1 195 ? -2.311  -34.86  7.81    1   27.78  ? 191 CYS A O   1 
ATOM   1569 C  CB  . CYS A 1 195 ? -1.943  -32.389 5.702   1   27.2   ? 191 CYS A CB  1 
ATOM   1570 S  SG  . CYS A 1 195 ? -1.487  -31.907 4.026   1   27.27  ? 191 CYS A SG  1 
ATOM   1571 N  N   . ILE A 1 196 ? -4.091  -33.452 7.833   1   26.58  ? 192 ILE A N   1 
ATOM   1572 C  CA  . ILE A 1 196 ? -4.406  -33.698 9.229   1   29.23  ? 192 ILE A CA  1 
ATOM   1573 C  C   . ILE A 1 196 ? -4.945  -35.114 9.44    1   30.51  ? 192 ILE A C   1 
ATOM   1574 O  O   . ILE A 1 196 ? -4.575  -35.776 10.416  1   26.88  ? 192 ILE A O   1 
ATOM   1575 C  CB  . ILE A 1 196 ? -5.334  -32.596 9.767   1   28.48  ? 192 ILE A CB  1 
ATOM   1576 C  CG1 . ILE A 1 196 ? -4.561  -31.27  9.812   1   29.29  ? 192 ILE A CG1 1 
ATOM   1577 C  CG2 . ILE A 1 196 ? -5.924  -32.974 11.157  1   28.36  ? 192 ILE A CG2 1 
ATOM   1578 C  CD1 . ILE A 1 196 ? -5.356  -30.101 9.947   1   30.53  ? 192 ILE A CD1 1 
ATOM   1579 N  N   . PHE A 1 197 ? -5.808  -35.566 8.518   1   29.46  ? 193 PHE A N   1 
ATOM   1580 C  CA  . PHE A 1 197 ? -6.292  -36.938 8.525   1   29.24  ? 193 PHE A CA  1 
ATOM   1581 C  C   . PHE A 1 197 ? -5.118  -37.923 8.61    1   29.11  ? 193 PHE A C   1 
ATOM   1582 O  O   . PHE A 1 197 ? -5.051  -38.752 9.519   1   29.27  ? 193 PHE A O   1 
ATOM   1583 C  CB  . PHE A 1 197 ? -7.137  -37.146 7.276   1   28.47  ? 193 PHE A CB  1 
ATOM   1584 C  CG  . PHE A 1 197 ? -7.796  -38.489 7.083   1   29.45  ? 193 PHE A CG  1 
ATOM   1585 C  CD1 . PHE A 1 197 ? -7.882  -39.401 8.125   1   29.13  ? 193 PHE A CD1 1 
ATOM   1586 C  CD2 . PHE A 1 197 ? -8.311  -38.857 5.842   1   27.32  ? 193 PHE A CD2 1 
ATOM   1587 C  CE1 . PHE A 1 197 ? -8.457  -40.655 7.926   1   27.83  ? 193 PHE A CE1 1 
ATOM   1588 C  CE2 . PHE A 1 197 ? -8.901  -40.102 5.66    1   27.17  ? 193 PHE A CE2 1 
ATOM   1589 C  CZ  . PHE A 1 197 ? -8.98   -40.988 6.709   1   27.23  ? 193 PHE A CZ  1 
ATOM   1590 N  N   . ALA A 1 198 ? -4.175  -37.803 7.673   1   26.45  ? 194 ALA A N   1 
ATOM   1591 C  CA  . ALA A 1 198 ? -2.993  -38.646 7.652   1   28.13  ? 194 ALA A CA  1 
ATOM   1592 C  C   . ALA A 1 198 ? -2.254  -38.597 8.988   1   27.1   ? 194 ALA A C   1 
ATOM   1593 O  O   . ALA A 1 198 ? -1.856  -39.634 9.528   1   29.33  ? 194 ALA A O   1 
ATOM   1594 C  CB  . ALA A 1 198 ? -2.069  -38.218 6.513   1   27.47  ? 194 ALA A CB  1 
ATOM   1595 N  N   . GLU A 1 199 ? -2.089  -37.375 9.507   1   26.26  ? 195 GLU A N   1 
ATOM   1596 C  CA  . GLU A 1 199 ? -1.333  -37.137 10.725  1   26.83  ? 195 GLU A CA  1 
ATOM   1597 C  C   . GLU A 1 199 ? -1.998  -37.771 11.946  1   28.18  ? 195 GLU A C   1 
ATOM   1598 O  O   . GLU A 1 199 ? -1.325  -38.307 12.825  1   28.61  ? 195 GLU A O   1 
ATOM   1599 C  CB  . GLU A 1 199 ? -1.138  -35.629 10.902  1   28.41  ? 195 GLU A CB  1 
ATOM   1600 C  CG  . GLU A 1 199 ? -0.182  -35.229 12.018  1   27.51  ? 195 GLU A CG  1 
ATOM   1601 C  CD  . GLU A 1 199 ? 0.265   -33.782 11.984  1   27.82  ? 195 GLU A CD  1 
ATOM   1602 O  OE1 . GLU A 1 199 ? 0.092   -33.133 10.929  1   29.77  ? 195 GLU A OE1 1 
ATOM   1603 O  OE2 . GLU A 1 199 ? 0.794   -33.297 13.009  1   27.41  ? 195 GLU A OE2 1 
ATOM   1604 N  N   . MET A 1 200 ? -3.33   -37.744 11.989  1   28.3   ? 196 MET A N   1 
ATOM   1605 C  CA  . MET A 1 200 ? -4.048  -38.452 13.035  1   27.23  ? 196 MET A CA  1 
ATOM   1606 C  C   . MET A 1 200 ? -3.766  -39.954 13.009  1   26.15  ? 196 MET A C   1 
ATOM   1607 O  O   . MET A 1 200 ? -3.741  -40.585 14.052  1   30.54  ? 196 MET A O   1 
ATOM   1608 C  CB  . MET A 1 200 ? -5.564  -38.178 12.916  1   27.25  ? 196 MET A CB  1 
ATOM   1609 C  CG  . MET A 1 200 ? -5.976  -36.862 13.573  1   26.87  ? 196 MET A CG  1 
ATOM   1610 S  SD  . MET A 1 200 ? -7.746  -36.681 13.754  1   26.63  ? 196 MET A SD  1 
ATOM   1611 C  CE  . MET A 1 200 ? -8.239  -36.681 12.038  1   30.16  ? 196 MET A CE  1 
ATOM   1612 N  N   . VAL A 1 201 ? -3.56   -40.529 11.821  1   27.31  ? 197 VAL A N   1 
ATOM   1613 C  CA  . VAL A 1 201 ? -3.333  -41.961 11.685  1   30.75  ? 197 VAL A CA  1 
ATOM   1614 C  C   . VAL A 1 201 ? -1.912  -42.366 12.086  1   33.2   ? 197 VAL A C   1 
ATOM   1615 O  O   . VAL A 1 201 ? -1.73   -43.384 12.745  1   32.85  ? 197 VAL A O   1 
ATOM   1616 C  CB  . VAL A 1 201 ? -3.642  -42.433 10.237  1   32.18  ? 197 VAL A CB  1 
ATOM   1617 C  CG1 . VAL A 1 201 ? -3.224  -43.876 10.031  1   33.49  ? 197 VAL A CG1 1 
ATOM   1618 C  CG2 . VAL A 1 201 ? -5.112  -42.242 9.878   1   31.05  ? 197 VAL A CG2 1 
ATOM   1619 N  N   . THR A 1 202 ? -0.918  -41.57  11.667  1   34.68  ? 198 THR A N   1 
ATOM   1620 C  CA  . THR A 1 202 ? 0.491   -41.852 11.908  1   34.18  ? 198 THR A CA  1 
ATOM   1621 C  C   . THR A 1 202 ? 1.102   -41.077 13.078  1   32.85  ? 198 THR A C   1 
ATOM   1622 O  O   . THR A 1 202 ? 2.151   -41.456 13.58   1   30.77  ? 198 THR A O   1 
ATOM   1623 C  CB  . THR A 1 202 ? 1.302   -41.515 10.647  1   36.58  ? 198 THR A CB  1 
ATOM   1624 O  OG1 . THR A 1 202 ? 1.285   -40.094 10.459  1   40.48  ? 198 THR A OG1 1 
ATOM   1625 C  CG2 . THR A 1 202 ? 0.761   -42.181 9.391   1   37.34  ? 198 THR A CG2 1 
ATOM   1626 N  N   . ARG A 1 203 ? 0.458   -39.972 13.477  1   33.47  ? 199 ARG A N   1 
ATOM   1627 C  CA  . ARG A 1 203 ? 0.991   -39.03  14.454  1   36.8   ? 199 ARG A CA  1 
ATOM   1628 C  C   . ARG A 1 203 ? 2.285   -38.339 14.022  1   35.12  ? 199 ARG A C   1 
ATOM   1629 O  O   . ARG A 1 203 ? 3.001   -37.81  14.861  1   35.91  ? 199 ARG A O   1 
ATOM   1630 C  CB  . ARG A 1 203 ? 1.206   -39.71  15.826  1   40.73  ? 199 ARG A CB  1 
ATOM   1631 C  CG  . ARG A 1 203 ? -0.058  -39.883 16.65   1   47.85  ? 199 ARG A CG  1 
ATOM   1632 C  CD  . ARG A 1 203 ? 0.013   -41.129 17.486  1   47.71  ? 199 ARG A CD  1 
ATOM   1633 N  NE  . ARG A 1 203 ? -0.176  -42.302 16.641  1   50.64  ? 199 ARG A NE  1 
ATOM   1634 C  CZ  . ARG A 1 203 ? 0.67    -43.316 16.543  1   50.73  ? 199 ARG A CZ  1 
ATOM   1635 N  NH1 . ARG A 1 203 ? 1.595   -43.538 17.461  1   51.07  ? 199 ARG A NH1 1 
ATOM   1636 N  NH2 . ARG A 1 203 ? 0.546   -44.162 15.527  1   55.77  ? 199 ARG A NH2 1 
ATOM   1637 N  N   . ARG A 1 204 ? 2.57    -38.323 12.716  1   36.72  ? 200 ARG A N   1 
ATOM   1638 C  CA  . ARG A 1 204 ? 3.634   -37.496 12.16   1   38.43  ? 200 ARG A CA  1 
ATOM   1639 C  C   . ARG A 1 204 ? 3.075   -36.701 10.983  1   33.85  ? 200 ARG A C   1 
ATOM   1640 O  O   . ARG A 1 204 ? 2.17    -37.165 10.298  1   34.1   ? 200 ARG A O   1 
ATOM   1641 C  CB  . ARG A 1 204 ? 4.826   -38.335 11.698  1   40.86  ? 200 ARG A CB  1 
ATOM   1642 C  CG  . ARG A 1 204 ? 4.484   -39.361 10.668  1   47.18  ? 200 ARG A CG  1 
ATOM   1643 C  CD  . ARG A 1 204 ? 5.706   -40.101 10.164  1   49.61  ? 200 ARG A CD  1 
ATOM   1644 N  NE  . ARG A 1 204 ? 5.39    -40.777 8.912   1   51.65  ? 200 ARG A NE  1 
ATOM   1645 C  CZ  . ARG A 1 204 ? 6.271   -41.399 8.146   1   48.23  ? 200 ARG A CZ  1 
ATOM   1646 N  NH1 . ARG A 1 204 ? 7.543   -41.483 8.49    1   47.9   ? 200 ARG A NH1 1 
ATOM   1647 N  NH2 . ARG A 1 204 ? 5.863   -41.958 7.008   1   48.02  ? 200 ARG A NH2 1 
ATOM   1648 N  N   . ALA A 1 205 ? 3.615   -35.501 10.762  1   30.72  ? 201 ALA A N   1 
ATOM   1649 C  CA  . ALA A 1 205 ? 3.201   -34.674 9.641   1   31.44  ? 201 ALA A CA  1 
ATOM   1650 C  C   . ALA A 1 205 ? 3.468   -35.413 8.334   1   28.05  ? 201 ALA A C   1 
ATOM   1651 O  O   . ALA A 1 205 ? 4.47    -36.097 8.213   1   28.93  ? 201 ALA A O   1 
ATOM   1652 C  CB  . ALA A 1 205 ? 3.925   -33.348 9.656   1   30.72  ? 201 ALA A CB  1 
ATOM   1653 N  N   . LEU A 1 206 ? 2.548   -35.289 7.378   1   27.04  ? 202 LEU A N   1 
ATOM   1654 C  CA  . LEU A 1 206 ? 2.645   -36.01  6.119   1   29.27  ? 202 LEU A CA  1 
ATOM   1655 C  C   . LEU A 1 206 ? 3.694   -35.405 5.19    1   27.74  ? 202 LEU A C   1 
ATOM   1656 O  O   . LEU A 1 206 ? 4.385   -36.125 4.491   1   31.35  ? 202 LEU A O   1 
ATOM   1657 C  CB  . LEU A 1 206 ? 1.256   -36.017 5.426   1   29.44  ? 202 LEU A CB  1 
ATOM   1658 C  CG  . LEU A 1 206 ? 1.167   -36.727 4.064   1   29.99  ? 202 LEU A CG  1 
ATOM   1659 C  CD1 . LEU A 1 206 ? 1.384   -38.207 4.208   1   27.91  ? 202 LEU A CD1 1 
ATOM   1660 C  CD2 . LEU A 1 206 ? -0.18   -36.492 3.418   1   30.6   ? 202 LEU A CD2 1 
ATOM   1661 N  N   . PHE A 1 207 ? 3.793   -34.076 5.177   1   27.35  ? 203 PHE A N   1 
ATOM   1662 C  CA  . PHE A 1 207 ? 4.733   -33.369 4.333   1   27.07  ? 203 PHE A CA  1 
ATOM   1663 C  C   . PHE A 1 207 ? 5.515   -32.334 5.132   1   27.4   ? 203 PHE A C   1 
ATOM   1664 O  O   . PHE A 1 207 ? 5.192   -31.149 5.079   1   28.18  ? 203 PHE A O   1 
ATOM   1665 C  CB  . PHE A 1 207 ? 3.96    -32.666 3.219   1   29.94  ? 203 PHE A CB  1 
ATOM   1666 C  CG  . PHE A 1 207 ? 3.102   -33.555 2.366   1   28.08  ? 203 PHE A CG  1 
ATOM   1667 C  CD1 . PHE A 1 207 ? 3.65    -34.633 1.699   1   28.07  ? 203 PHE A CD1 1 
ATOM   1668 C  CD2 . PHE A 1 207 ? 1.758   -33.284 2.192   1   28.64  ? 203 PHE A CD2 1 
ATOM   1669 C  CE1 . PHE A 1 207 ? 2.873   -35.417 0.882   1   27.81  ? 203 PHE A CE1 1 
ATOM   1670 C  CE2 . PHE A 1 207 ? 0.977   -34.09  1.381   1   28.89  ? 203 PHE A CE2 1 
ATOM   1671 C  CZ  . PHE A 1 207 ? 1.541   -35.14  0.721   1   27.93  ? 203 PHE A CZ  1 
ATOM   1672 N  N   . PRO A 1 208 ? 6.549   -32.737 5.905   1   25.73  ? 204 PRO A N   1 
ATOM   1673 C  CA  . PRO A 1 208 ? 7.279   -31.8   6.769   1   23.5   ? 204 PRO A CA  1 
ATOM   1674 C  C   . PRO A 1 208 ? 8.415   -31.084 6.052   1   24.47  ? 204 PRO A C   1 
ATOM   1675 O  O   . PRO A 1 208 ? 9.587   -31.338 6.312   1   21.94  ? 204 PRO A O   1 
ATOM   1676 C  CB  . PRO A 1 208 ? 7.817   -32.716 7.883   1   23.64  ? 204 PRO A CB  1 
ATOM   1677 C  CG  . PRO A 1 208 ? 8.069   -34.059 7.161   1   22.97  ? 204 PRO A CG  1 
ATOM   1678 C  CD  . PRO A 1 208 ? 7.026   -34.131 6.03    1   24.01  ? 204 PRO A CD  1 
ATOM   1679 N  N   . GLY A 1 209 ? 8.055   -30.169 5.168   1   27.55  ? 205 GLY A N   1 
ATOM   1680 C  CA  . GLY A 1 209 ? 9.06    -29.443 4.383   1   29.96  ? 205 GLY A CA  1 
ATOM   1681 C  C   . GLY A 1 209 ? 9.804   -28.395 5.175   1   29.92  ? 205 GLY A C   1 
ATOM   1682 O  O   . GLY A 1 209 ? 9.254   -27.896 6.168   1   28.56  ? 205 GLY A O   1 
ATOM   1683 N  N   . ASP A 1 210 ? 11.015  -28.065 4.73    1   35.04  ? 206 ASP A N   1 
ATOM   1684 C  CA  . ASP A 1 210 ? 11.846  -27.038 5.41    1   41.64  ? 206 ASP A CA  1 
ATOM   1685 C  C   . ASP A 1 210 ? 11.816  -25.756 4.581   1   37.23  ? 206 ASP A C   1 
ATOM   1686 O  O   . ASP A 1 210 ? 12.368  -24.745 5.04    1   41.22  ? 206 ASP A O   1 
ATOM   1687 C  CB  . ASP A 1 210 ? 13.258  -27.546 5.631   1   48.21  ? 206 ASP A CB  1 
ATOM   1688 C  CG  . ASP A 1 210 ? 13.381  -29.016 6.003   1   63.17  ? 206 ASP A CG  1 
ATOM   1689 O  OD1 . ASP A 1 210 ? 13.973  -29.775 5.21    1   82.88  ? 206 ASP A OD1 1 
ATOM   1690 O  OD2 . ASP A 1 210 ? 12.888  -29.388 7.086   1   63.7   ? 206 ASP A OD2 1 
ATOM   1691 N  N   . SER A 1 211 ? 11.172  -25.806 3.422   1   32.43  ? 207 SER A N   1 
ATOM   1692 C  CA  . SER A 1 211 ? 11.143  -24.64  2.517   1   28.57  ? 207 SER A CA  1 
ATOM   1693 C  C   . SER A 1 211 ? 9.979   -24.778 1.541   1   26.39  ? 207 SER A C   1 
ATOM   1694 O  O   . SER A 1 211 ? 9.45    -25.883 1.426   1   29.01  ? 207 SER A O   1 
ATOM   1695 C  CB  . SER A 1 211 ? 12.435  -24.543 1.763   1   27.6   ? 207 SER A CB  1 
ATOM   1696 O  OG  . SER A 1 211 ? 12.394  -25.293 0.562   1   26.69  ? 207 SER A OG  1 
ATOM   1697 N  N   . GLU A 1 212 ? 9.595   -23.689 0.888   1   26.69  ? 208 GLU A N   1 
ATOM   1698 C  CA  . GLU A 1 212 ? 8.596   -23.798 -0.162  1   28.66  ? 208 GLU A CA  1 
ATOM   1699 C  C   . GLU A 1 212 ? 8.95    -24.864 -1.201  1   27.65  ? 208 GLU A C   1 
ATOM   1700 O  O   . GLU A 1 212 ? 8.121   -25.707 -1.542  1   27.86  ? 208 GLU A O   1 
ATOM   1701 C  CB  . GLU A 1 212 ? 8.403   -22.449 -0.855  1   31.03  ? 208 GLU A CB  1 
ATOM   1702 C  CG  . GLU A 1 212 ? 7.481   -21.502 -0.114  1   35.25  ? 208 GLU A CG  1 
ATOM   1703 C  CD  . GLU A 1 212 ? 7.343   -20.124 -0.747  1   38.07  ? 208 GLU A CD  1 
ATOM   1704 O  OE1 . GLU A 1 212 ? 8.338   -19.368 -0.71   1   47.34  ? 208 GLU A OE1 1 
ATOM   1705 O  OE2 . GLU A 1 212 ? 6.261   -19.792 -1.286  1   41.84  ? 208 GLU A OE2 1 
ATOM   1706 N  N   . ILE A 1 213 ? 10.183  -24.835 -1.708  1   27.69  ? 209 ILE A N   1 
ATOM   1707 C  CA  . ILE A 1 213 ? 10.555  -25.764 -2.758  1   28.33  ? 209 ILE A CA  1 
ATOM   1708 C  C   . ILE A 1 213 ? 10.67   -27.181 -2.197  1   26.36  ? 209 ILE A C   1 
ATOM   1709 O  O   . ILE A 1 213 ? 10.255  -28.13  -2.848  1   26.49  ? 209 ILE A O   1 
ATOM   1710 C  CB  . ILE A 1 213 ? 11.818  -25.324 -3.529  1   32.17  ? 209 ILE A CB  1 
ATOM   1711 C  CG1 . ILE A 1 213 ? 11.977  -26.18  -4.775  1   35.83  ? 209 ILE A CG1 1 
ATOM   1712 C  CG2 . ILE A 1 213 ? 13.071  -25.365 -2.686  1   33.69  ? 209 ILE A CG2 1 
ATOM   1713 C  CD1 . ILE A 1 213 ? 10.811  -25.99  -5.809  1   39.69  ? 209 ILE A CD1 1 
ATOM   1714 N  N   . ASP A 1 214 ? 11.195  -27.323 -0.977  1   26.87  ? 210 ASP A N   1 
ATOM   1715 C  CA  . ASP A 1 214 ? 11.275  -28.621 -0.324  1   26.23  ? 210 ASP A CA  1 
ATOM   1716 C  C   . ASP A 1 214 ? 9.884   -29.186 -0.046  1   25.15  ? 210 ASP A C   1 
ATOM   1717 O  O   . ASP A 1 214 ? 9.639   -30.38  -0.234  1   24.76  ? 210 ASP A O   1 
ATOM   1718 C  CB  . ASP A 1 214 ? 12.09   -28.529 0.968   1   31.2   ? 210 ASP A CB  1 
ATOM   1719 C  CG  . ASP A 1 214 ? 12.266  -29.864 1.678   1   35.71  ? 210 ASP A CG  1 
ATOM   1720 O  OD1 . ASP A 1 214 ? 12.818  -30.786 1.064   1   35.97  ? 210 ASP A OD1 1 
ATOM   1721 O  OD2 . ASP A 1 214 ? 11.829  -29.984 2.851   1   39.41  ? 210 ASP A OD2 1 
ATOM   1722 N  N   . GLN A 1 215 ? 8.964   -28.315 0.377   1   24.84  ? 211 GLN A N   1 
ATOM   1723 C  CA  . GLN A 1 215 ? 7.578   -28.707 0.587   1   25.41  ? 211 GLN A CA  1 
ATOM   1724 C  C   . GLN A 1 215 ? 6.964   -29.28  -0.691  1   24.91  ? 211 GLN A C   1 
ATOM   1725 O  O   . GLN A 1 215 ? 6.354   -30.341 -0.657  1   25.22  ? 211 GLN A O   1 
ATOM   1726 C  CB  . GLN A 1 215 ? 6.777   -27.496 1.09    1   24.89  ? 211 GLN A CB  1 
ATOM   1727 C  CG  . GLN A 1 215 ? 5.36    -27.776 1.534   1   24.11  ? 211 GLN A CG  1 
ATOM   1728 C  CD  . GLN A 1 215 ? 5.323   -28.667 2.719   1   25.47  ? 211 GLN A CD  1 
ATOM   1729 O  OE1 . GLN A 1 215 ? 6.172   -28.586 3.59    1   28.35  ? 211 GLN A OE1 1 
ATOM   1730 N  NE2 . GLN A 1 215 ? 4.345   -29.539 2.786   1   27.77  ? 211 GLN A NE2 1 
ATOM   1731 N  N   . LEU A 1 216 ? 7.131   -28.576 -1.818  1   26     ? 212 LEU A N   1 
ATOM   1732 C  CA  . LEU A 1 216 ? 6.626   -29.044 -3.1    1   28.24  ? 212 LEU A CA  1 
ATOM   1733 C  C   . LEU A 1 216 ? 7.197   -30.411 -3.441  1   26.61  ? 212 LEU A C   1 
ATOM   1734 O  O   . LEU A 1 216 ? 6.454   -31.301 -3.822  1   25.11  ? 212 LEU A O   1 
ATOM   1735 C  CB  . LEU A 1 216 ? 7.02    -28.106 -4.258  1   30.92  ? 212 LEU A CB  1 
ATOM   1736 C  CG  . LEU A 1 216 ? 6.116   -26.977 -4.589  1   35.7   ? 212 LEU A CG  1 
ATOM   1737 C  CD1 . LEU A 1 216 ? 6.696   -26.196 -5.725  1   36.32  ? 212 LEU A CD1 1 
ATOM   1738 C  CD2 . LEU A 1 216 ? 4.692   -27.468 -4.948  1   36.6   ? 212 LEU A CD2 1 
ATOM   1739 N  N   . PHE A 1 217 ? 8.528   -30.536 -3.344  1   25.58  ? 213 PHE A N   1 
ATOM   1740 C  CA  . PHE A 1 217 ? 9.213   -31.75  -3.744  1   24.47  ? 213 PHE A CA  1 
ATOM   1741 C  C   . PHE A 1 217 ? 8.764   -32.925 -2.883  1   26.94  ? 213 PHE A C   1 
ATOM   1742 O  O   . PHE A 1 217 ? 8.627   -34.03  -3.397  1   29.45  ? 213 PHE A O   1 
ATOM   1743 C  CB  . PHE A 1 217 ? 10.75   -31.541 -3.762  1   22.31  ? 213 PHE A CB  1 
ATOM   1744 C  CG  . PHE A 1 217 ? 11.276  -30.699 -4.925  1   22.45  ? 213 PHE A CG  1 
ATOM   1745 C  CD1 . PHE A 1 217 ? 10.415  -30.167 -5.877  1   21.71  ? 213 PHE A CD1 1 
ATOM   1746 C  CD2 . PHE A 1 217 ? 12.622  -30.42  -5.048  1   24.54  ? 213 PHE A CD2 1 
ATOM   1747 C  CE1 . PHE A 1 217 ? 10.896  -29.4   -6.929  1   21.73  ? 213 PHE A CE1 1 
ATOM   1748 C  CE2 . PHE A 1 217 ? 13.099  -29.643 -6.109  1   22.98  ? 213 PHE A CE2 1 
ATOM   1749 C  CZ  . PHE A 1 217 ? 12.227  -29.131 -7.033  1   21.62  ? 213 PHE A CZ  1 
ATOM   1750 N  N   . ARG A 1 218 ? 8.49    -32.691 -1.595  1   27.82  ? 214 ARG A N   1 
ATOM   1751 C  CA  . ARG A 1 218 ? 7.981   -33.756 -0.738  1   30.54  ? 214 ARG A CA  1 
ATOM   1752 C  C   . ARG A 1 218 ? 6.594   -34.236 -1.149  1   27.43  ? 214 ARG A C   1 
ATOM   1753 O  O   . ARG A 1 218 ? 6.319   -35.425 -1.096  1   27.36  ? 214 ARG A O   1 
ATOM   1754 C  CB  . ARG A 1 218 ? 7.928   -33.322 0.742   1   33.5   ? 214 ARG A CB  1 
ATOM   1755 C  CG  . ARG A 1 218 ? 9.265   -33.336 1.411   1   32.37  ? 214 ARG A CG  1 
ATOM   1756 C  CD  . ARG A 1 218 ? 9.161   -32.92  2.836   1   32.55  ? 214 ARG A CD  1 
ATOM   1757 N  NE  . ARG A 1 218 ? 10.495  -32.659 3.353   1   31.87  ? 214 ARG A NE  1 
ATOM   1758 C  CZ  . ARG A 1 218 ? 11.122  -33.45  4.208   1   30.31  ? 214 ARG A CZ  1 
ATOM   1759 N  NH1 . ARG A 1 218 ? 10.581  -34.585 4.624   1   32.41  ? 214 ARG A NH1 1 
ATOM   1760 N  NH2 . ARG A 1 218 ? 12.313  -33.088 4.67    1   25.32  ? 214 ARG A NH2 1 
ATOM   1761 N  N   . ILE A 1 219 ? 5.719   -33.297 -1.519  1   27.92  ? 215 ILE A N   1 
ATOM   1762 C  CA  . ILE A 1 219 ? 4.405   -33.636 -2.042  1   27.02  ? 215 ILE A CA  1 
ATOM   1763 C  C   . ILE A 1 219 ? 4.537   -34.469 -3.319  1   27.01  ? 215 ILE A C   1 
ATOM   1764 O  O   . ILE A 1 219 ? 3.893   -35.509 -3.441  1   25.75  ? 215 ILE A O   1 
ATOM   1765 C  CB  . ILE A 1 219 ? 3.573   -32.352 -2.255  1   27.32  ? 215 ILE A CB  1 
ATOM   1766 C  CG1 . ILE A 1 219 ? 3.301   -31.645 -0.917  1   28.32  ? 215 ILE A CG1 1 
ATOM   1767 C  CG2 . ILE A 1 219 ? 2.261   -32.664 -2.998  1   27.69  ? 215 ILE A CG2 1 
ATOM   1768 C  CD1 . ILE A 1 219 ? 2.784   -30.202 -1.045  1   31.67  ? 215 ILE A CD1 1 
ATOM   1769 N  N   . PHE A 1 220 ? 5.399   -34.019 -4.241  1   24.25  ? 216 PHE A N   1 
ATOM   1770 C  CA  . PHE A 1 220 ? 5.621   -34.687 -5.512  1   24.09  ? 216 PHE A CA  1 
ATOM   1771 C  C   . PHE A 1 220 ? 6.164   -36.105 -5.359  1   25.9   ? 216 PHE A C   1 
ATOM   1772 O  O   . PHE A 1 220 ? 5.719   -37.01  -6.059  1   27.58  ? 216 PHE A O   1 
ATOM   1773 C  CB  . PHE A 1 220 ? 6.605   -33.897 -6.391  1   23.53  ? 216 PHE A CB  1 
ATOM   1774 C  CG  . PHE A 1 220 ? 6.157   -32.564 -6.945  1   22.79  ? 216 PHE A CG  1 
ATOM   1775 C  CD1 . PHE A 1 220 ? 4.899   -32.072 -6.683  1   21.88  ? 216 PHE A CD1 1 
ATOM   1776 C  CD2 . PHE A 1 220 ? 7.016   -31.792 -7.714  1   23.91  ? 216 PHE A CD2 1 
ATOM   1777 C  CE1 . PHE A 1 220 ? 4.504   -30.836 -7.199  1   23.34  ? 216 PHE A CE1 1 
ATOM   1778 C  CE2 . PHE A 1 220 ? 6.607   -30.56  -8.238  1   22.62  ? 216 PHE A CE2 1 
ATOM   1779 C  CZ  . PHE A 1 220 ? 5.366   -30.087 -7.959  1   21.7   ? 216 PHE A CZ  1 
ATOM   1780 N  N   . ARG A 1 221 ? 7.12    -36.299 -4.45   1   26.51  ? 217 ARG A N   1 
ATOM   1781 C  CA  . ARG A 1 221 ? 7.707   -37.611 -4.234  1   26.87  ? 217 ARG A CA  1 
ATOM   1782 C  C   . ARG A 1 221 ? 6.694   -38.582 -3.632  1   26.29  ? 217 ARG A C   1 
ATOM   1783 O  O   . ARG A 1 221 ? 6.837   -39.787 -3.746  1   30     ? 217 ARG A O   1 
ATOM   1784 C  CB  . ARG A 1 221 ? 8.969   -37.51  -3.348  1   25.4   ? 217 ARG A CB  1 
ATOM   1785 C  CG  . ARG A 1 221 ? 10.175  -36.995 -4.101  1   26.07  ? 217 ARG A CG  1 
ATOM   1786 C  CD  . ARG A 1 221 ? 11.491  -37.32  -3.414  1   26.84  ? 217 ARG A CD  1 
ATOM   1787 N  NE  . ARG A 1 221 ? 11.593  -36.654 -2.122  1   30.41  ? 217 ARG A NE  1 
ATOM   1788 C  CZ  . ARG A 1 221 ? 11.902  -35.372 -1.942  1   31.5   ? 217 ARG A CZ  1 
ATOM   1789 N  NH1 . ARG A 1 221 ? 12.536  -34.666 -2.869  1   30.18  ? 217 ARG A NH1 1 
ATOM   1790 N  NH2 . ARG A 1 221 ? 11.629  -34.805 -0.773  1   30.98  ? 217 ARG A NH2 1 
ATOM   1791 N  N   . THR A 1 222 ? 5.643   -38.051 -3.017  1   29.38  ? 218 THR A N   1 
ATOM   1792 C  CA  . THR A 1 222 ? 4.579   -38.874 -2.466  1   28.73  ? 218 THR A CA  1 
ATOM   1793 C  C   . THR A 1 222 ? 3.416   -39.121 -3.424  1   28.47  ? 218 THR A C   1 
ATOM   1794 O  O   . THR A 1 222 ? 2.896   -40.225 -3.479  1   30.91  ? 218 THR A O   1 
ATOM   1795 C  CB  . THR A 1 222 ? 4.068   -38.221 -1.19   1   26.85  ? 218 THR A CB  1 
ATOM   1796 O  OG1 . THR A 1 222 ? 5.168   -38.143 -0.285  1   23.4   ? 218 THR A OG1 1 
ATOM   1797 C  CG2 . THR A 1 222 ? 2.891   -38.979 -0.574  1   28.98  ? 218 THR A CG2 1 
ATOM   1798 N  N   . LEU A 1 223 ? 2.973   -38.076 -4.129  1   28.12  ? 219 LEU A N   1 
ATOM   1799 C  CA  . LEU A 1 223 ? 1.774   -38.139 -4.948  1   28.7   ? 219 LEU A CA  1 
ATOM   1800 C  C   . LEU A 1 223 ? 2.076   -38.184 -6.449  1   29.38  ? 219 LEU A C   1 
ATOM   1801 O  O   . LEU A 1 223 ? 1.153   -38.196 -7.268  1   27.32  ? 219 LEU A O   1 
ATOM   1802 C  CB  . LEU A 1 223 ? 0.904   -36.898 -4.64   1   28.94  ? 219 LEU A CB  1 
ATOM   1803 C  CG  . LEU A 1 223 ? 0.409   -36.728 -3.203  1   30.98  ? 219 LEU A CG  1 
ATOM   1804 C  CD1 . LEU A 1 223 ? -0.434  -35.498 -3.055  1   30.07  ? 219 LEU A CD1 1 
ATOM   1805 C  CD2 . LEU A 1 223 ? -0.426  -37.921 -2.741  1   35.13  ? 219 LEU A CD2 1 
ATOM   1806 N  N   . GLY A 1 224 ? 3.367   -38.147 -6.797  1   27.45  ? 220 GLY A N   1 
ATOM   1807 C  CA  . GLY A 1 224 ? 3.819   -37.998 -8.171  1   25.72  ? 220 GLY A CA  1 
ATOM   1808 C  C   . GLY A 1 224 ? 3.89    -36.538 -8.595  1   25.43  ? 220 GLY A C   1 
ATOM   1809 O  O   . GLY A 1 224 ? 3.1     -35.732 -8.131  1   24.25  ? 220 GLY A O   1 
ATOM   1810 N  N   . THR A 1 225 ? 4.845   -36.199 -9.468  1   25.6   ? 221 THR A N   1 
ATOM   1811 C  CA  . THR A 1 225 ? 4.948   -34.844 -9.983  1   27.77  ? 221 THR A CA  1 
ATOM   1812 C  C   . THR A 1 225 ? 3.765   -34.667 -10.928 1   29.01  ? 221 THR A C   1 
ATOM   1813 O  O   . THR A 1 225 ? 3.582   -35.468 -11.834 1   30.86  ? 221 THR A O   1 
ATOM   1814 C  CB  . THR A 1 225 ? 6.281   -34.576 -10.677 1   29.23  ? 221 THR A CB  1 
ATOM   1815 O  OG1 . THR A 1 225 ? 7.381   -34.855 -9.772  1   28.17  ? 221 THR A OG1 1 
ATOM   1816 C  CG2 . THR A 1 225 ? 6.372   -33.141 -11.211 1   28.37  ? 221 THR A CG2 1 
ATOM   1817 N  N   . PRO A 1 226 ? 2.907   -33.641 -10.73  1   29.33  ? 222 PRO A N   1 
ATOM   1818 C  CA  . PRO A 1 226 ? 1.73    -33.454 -11.573 1   30.28  ? 222 PRO A CA  1 
ATOM   1819 C  C   . PRO A 1 226 ? 2.106   -32.939 -12.958 1   28.06  ? 222 PRO A C   1 
ATOM   1820 O  O   . PRO A 1 226 ? 3.089   -32.222 -13.109 1   25.36  ? 222 PRO A O   1 
ATOM   1821 C  CB  . PRO A 1 226 ? 0.917   -32.427 -10.785 1   30.22  ? 222 PRO A CB  1 
ATOM   1822 C  CG  . PRO A 1 226 ? 1.977   -31.618 -10.051 1   29.68  ? 222 PRO A CG  1 
ATOM   1823 C  CD  . PRO A 1 226 ? 3.033   -32.6   -9.698  1   28.96  ? 222 PRO A CD  1 
ATOM   1824 N  N   . ASP A 1 227 ? 1.302   -33.329 -13.948 1   29.15  ? 223 ASP A N   1 
ATOM   1825 C  CA  . ASP A 1 227 ? 1.442   -32.903 -15.331 1   30.55  ? 223 ASP A CA  1 
ATOM   1826 C  C   . ASP A 1 227 ? 0.066   -32.442 -15.811 1   28.16  ? 223 ASP A C   1 
ATOM   1827 O  O   . ASP A 1 227 ? -0.872  -32.363 -15.019 1   28.18  ? 223 ASP A O   1 
ATOM   1828 C  CB  . ASP A 1 227 ? 1.997   -34.074 -16.177 1   30.22  ? 223 ASP A CB  1 
ATOM   1829 C  CG  . ASP A 1 227 ? 1.097   -35.299 -16.208 1   33.17  ? 223 ASP A CG  1 
ATOM   1830 O  OD1 . ASP A 1 227 ? -0.038  -35.204 -15.763 1   34.6   ? 223 ASP A OD1 1 
ATOM   1831 O  OD2 . ASP A 1 227 ? 1.538   -36.346 -16.685 1   40.26  ? 223 ASP A OD2 1 
ATOM   1832 N  N   . GLU A 1 228 ? -0.053  -32.154 -17.108 1   28.62  ? 224 GLU A N   1 
ATOM   1833 C  CA  . GLU A 1 228 ? -1.28   -31.592 -17.652 1   29.74  ? 224 GLU A CA  1 
ATOM   1834 C  C   . GLU A 1 228 ? -2.473  -32.545 -17.577 1   30.11  ? 224 GLU A C   1 
ATOM   1835 O  O   . GLU A 1 228 ? -3.606  -32.084 -17.455 1   31.51  ? 224 GLU A O   1 
ATOM   1836 C  CB  . GLU A 1 228 ? -1.045  -31.119 -19.09  1   30.14  ? 224 GLU A CB  1 
ATOM   1837 C  CG  . GLU A 1 228 ? -0.267  -29.828 -19.149 1   30.48  ? 224 GLU A CG  1 
ATOM   1838 C  CD  . GLU A 1 228 ? -0.987  -28.613 -18.591 1   34.09  ? 224 GLU A CD  1 
ATOM   1839 O  OE1 . GLU A 1 228 ? -2.24   -28.608 -18.526 1   34.71  ? 224 GLU A OE1 1 
ATOM   1840 O  OE2 . GLU A 1 228 ? -0.279  -27.661 -18.192 1   35.43  ? 224 GLU A OE2 1 
ATOM   1841 N  N   . VAL A 1 229 ? -2.207  -33.859 -17.599 1   31.19  ? 225 VAL A N   1 
ATOM   1842 C  CA  . VAL A 1 229 ? -3.257  -34.863 -17.538 1   32.58  ? 225 VAL A CA  1 
ATOM   1843 C  C   . VAL A 1 229 ? -3.918  -34.925 -16.162 1   33.83  ? 225 VAL A C   1 
ATOM   1844 O  O   . VAL A 1 229 ? -5.135  -35.026 -16.056 1   34.23  ? 225 VAL A O   1 
ATOM   1845 C  CB  . VAL A 1 229 ? -2.709  -36.259 -17.925 1   35.24  ? 225 VAL A CB  1 
ATOM   1846 C  CG1 . VAL A 1 229 ? -3.768  -37.351 -17.697 1   33.45  ? 225 VAL A CG1 1 
ATOM   1847 C  CG2 . VAL A 1 229 ? -2.182  -36.259 -19.362 1   34.03  ? 225 VAL A CG2 1 
ATOM   1848 N  N   . VAL A 1 230 ? -3.11   -34.902 -15.101 1   34.52  ? 226 VAL A N   1 
ATOM   1849 C  CA  . VAL A 1 230 ? -3.661  -34.981 -13.76  1   37.04  ? 226 VAL A CA  1 
ATOM   1850 C  C   . VAL A 1 230 ? -4.139  -33.605 -13.304 1   36.33  ? 226 VAL A C   1 
ATOM   1851 O  O   . VAL A 1 230 ? -5.114  -33.505 -12.563 1   36.01  ? 226 VAL A O   1 
ATOM   1852 C  CB  . VAL A 1 230 ? -2.673  -35.628 -12.764 1   41.44  ? 226 VAL A CB  1 
ATOM   1853 C  CG1 . VAL A 1 230 ? -1.361  -34.904 -12.735 1   43.59  ? 226 VAL A CG1 1 
ATOM   1854 C  CG2 . VAL A 1 230 ? -3.267  -35.712 -11.367 1   45.6   ? 226 VAL A CG2 1 
ATOM   1855 N  N   . TRP A 1 231 ? -3.469  -32.544 -13.766 1   34.93  ? 227 TRP A N   1 
ATOM   1856 C  CA  . TRP A 1 231 ? -3.791  -31.202 -13.315 1   35.03  ? 227 TRP A CA  1 
ATOM   1857 C  C   . TRP A 1 231 ? -3.686  -30.208 -14.466 1   31.93  ? 227 TRP A C   1 
ATOM   1858 O  O   . TRP A 1 231 ? -2.64   -29.589 -14.673 1   30.42  ? 227 TRP A O   1 
ATOM   1859 C  CB  . TRP A 1 231 ? -2.885  -30.811 -12.136 1   34.55  ? 227 TRP A CB  1 
ATOM   1860 C  CG  . TRP A 1 231 ? -3.242  -29.516 -11.483 1   33.36  ? 227 TRP A CG  1 
ATOM   1861 C  CD1 . TRP A 1 231 ? -4.259  -28.672 -11.814 1   31.92  ? 227 TRP A CD1 1 
ATOM   1862 C  CD2 . TRP A 1 231 ? -2.545  -28.903 -10.395 1   33.46  ? 227 TRP A CD2 1 
ATOM   1863 N  NE1 . TRP A 1 231 ? -4.229  -27.563 -11.008 1   32.63  ? 227 TRP A NE1 1 
ATOM   1864 C  CE2 . TRP A 1 231 ? -3.202  -27.69  -10.11  1   32.45  ? 227 TRP A CE2 1 
ATOM   1865 C  CE3 . TRP A 1 231 ? -1.436  -29.271 -9.622  1   33.45  ? 227 TRP A CE3 1 
ATOM   1866 C  CZ2 . TRP A 1 231 ? -2.797  -26.85  -9.079  1   32.19  ? 227 TRP A CZ2 1 
ATOM   1867 C  CZ3 . TRP A 1 231 ? -1.029  -28.437 -8.609  1   36.35  ? 227 TRP A CZ3 1 
ATOM   1868 C  CH2 . TRP A 1 231 ? -1.7    -27.236 -8.348  1   36.44  ? 227 TRP A CH2 1 
ATOM   1869 N  N   . PRO A 1 232 ? -4.764  -30.044 -15.261 1   34.49  ? 228 PRO A N   1 
ATOM   1870 C  CA  . PRO A 1 232 ? -4.755  -29.08  -16.365 1   38.43  ? 228 PRO A CA  1 
ATOM   1871 C  C   . PRO A 1 232 ? -4.422  -27.673 -15.873 1   38.6   ? 228 PRO A C   1 
ATOM   1872 O  O   . PRO A 1 232 ? -5.034  -27.186 -14.923 1   36.37  ? 228 PRO A O   1 
ATOM   1873 C  CB  . PRO A 1 232 ? -6.179  -29.177 -16.958 1   37.89  ? 228 PRO A CB  1 
ATOM   1874 C  CG  . PRO A 1 232 ? -6.732  -30.518 -16.455 1   38.06  ? 228 PRO A CG  1 
ATOM   1875 C  CD  . PRO A 1 232 ? -6.031  -30.789 -15.142 1   38.03  ? 228 PRO A CD  1 
ATOM   1876 N  N   . GLY A 1 233 ? -3.437  -27.04  -16.526 1   41.77  ? 229 GLY A N   1 
ATOM   1877 C  CA  . GLY A 1 233 ? -2.98   -25.714 -16.142 1   43.2   ? 229 GLY A CA  1 
ATOM   1878 C  C   . GLY A 1 233 ? -1.699  -25.677 -15.307 1   44.56  ? 229 GLY A C   1 
ATOM   1879 O  O   . GLY A 1 233 ? -1.032  -24.649 -15.281 1   47.65  ? 229 GLY A O   1 
ATOM   1880 N  N   . VAL A 1 234 ? -1.352  -26.791 -14.641 1   40.52  ? 230 VAL A N   1 
ATOM   1881 C  CA  . VAL A 1 234 ? -0.231  -26.819 -13.711 1   35.55  ? 230 VAL A CA  1 
ATOM   1882 C  C   . VAL A 1 234 ? 1.048   -26.26  -14.341 1   37.11  ? 230 VAL A C   1 
ATOM   1883 O  O   . VAL A 1 234 ? 1.739   -25.466 -13.71  1   35.38  ? 230 VAL A O   1 
ATOM   1884 C  CB  . VAL A 1 234 ? -0.013  -28.235 -13.099 1   32.62  ? 230 VAL A CB  1 
ATOM   1885 C  CG1 . VAL A 1 234 ? 0.517   -29.237 -14.13  1   30.18  ? 230 VAL A CG1 1 
ATOM   1886 C  CG2 . VAL A 1 234 ? 0.917   -28.171 -11.89  1   34.2   ? 230 VAL A CG2 1 
ATOM   1887 N  N   . THR A 1 235 ? 1.336   -26.622 -15.601 1   39.77  ? 231 THR A N   1 
ATOM   1888 C  CA  . THR A 1 235 ? 2.572   -26.186 -16.247 1   39.86  ? 231 THR A CA  1 
ATOM   1889 C  C   . THR A 1 235 ? 2.59    -24.702 -16.626 1   41.21  ? 231 THR A C   1 
ATOM   1890 O  O   . THR A 1 235 ? 3.644   -24.178 -16.972 1   43.19  ? 231 THR A O   1 
ATOM   1891 C  CB  . THR A 1 235 ? 2.923   -27.015 -17.516 1   38.03  ? 231 THR A CB  1 
ATOM   1892 O  OG1 . THR A 1 235 ? 1.891   -26.832 -18.483 1   40.63  ? 231 THR A OG1 1 
ATOM   1893 C  CG2 . THR A 1 235 ? 3.12    -28.505 -17.221 1   35.75  ? 231 THR A CG2 1 
ATOM   1894 N  N   . SER A 1 236 ? 1.432   -24.031 -16.563 1   38.75  ? 232 SER A N   1 
ATOM   1895 C  CA  . SER A 1 236 ? 1.325   -22.607 -16.84  1   45.22  ? 232 SER A CA  1 
ATOM   1896 C  C   . SER A 1 236 ? 1.318   -21.747 -15.58  1   47.43  ? 232 SER A C   1 
ATOM   1897 O  O   . SER A 1 236 ? 1.183   -20.532 -15.672 1   51.02  ? 232 SER A O   1 
ATOM   1898 C  CB  . SER A 1 236 ? 0.02    -22.303 -17.578 1   48.72  ? 232 SER A CB  1 
ATOM   1899 O  OG  . SER A 1 236 ? -0.117  -23.002 -18.801 1   55.08  ? 232 SER A OG  1 
ATOM   1900 N  N   . MET A 1 237 ? 1.457   -22.378 -14.408 1   46.66  ? 233 MET A N   1 
ATOM   1901 C  CA  . MET A 1 237 ? 1.317   -21.67  -13.147 1   43.98  ? 233 MET A CA  1 
ATOM   1902 C  C   . MET A 1 237 ? 2.57    -20.851 -12.863 1   37.96  ? 233 MET A C   1 
ATOM   1903 O  O   . MET A 1 237 ? 3.665   -21.246 -13.252 1   34.59  ? 233 MET A O   1 
ATOM   1904 C  CB  . MET A 1 237 ? 1.011   -22.66  -12.038 1   44.54  ? 233 MET A CB  1 
ATOM   1905 C  CG  . MET A 1 237 ? -0.311  -23.272 -12.301 1   48.03  ? 233 MET A CG  1 
ATOM   1906 S  SD  . MET A 1 237 ? -0.998  -24.23  -11.008 1   51.48  ? 233 MET A SD  1 
ATOM   1907 C  CE  . MET A 1 237 ? -2.532  -24.781 -11.793 1   58.02  ? 233 MET A CE  1 
ATOM   1908 N  N   . PRO A 1 238 ? 2.438   -19.669 -12.219 1   36.46  ? 234 PRO A N   1 
ATOM   1909 C  CA  . PRO A 1 238 ? 3.546   -18.71  -12.156 1   34.29  ? 234 PRO A CA  1 
ATOM   1910 C  C   . PRO A 1 238 ? 4.884   -19.304 -11.716 1   31.9   ? 234 PRO A C   1 
ATOM   1911 O  O   . PRO A 1 238 ? 5.913   -19.013 -12.317 1   36.6   ? 234 PRO A O   1 
ATOM   1912 C  CB  . PRO A 1 238 ? 3.03    -17.649 -11.178 1   35.15  ? 234 PRO A CB  1 
ATOM   1913 C  CG  . PRO A 1 238 ? 1.524   -17.731 -11.292 1   35.3   ? 234 PRO A CG  1 
ATOM   1914 C  CD  . PRO A 1 238 ? 1.231   -19.198 -11.507 1   36.2   ? 234 PRO A CD  1 
ATOM   1915 N  N   . ASP A 1 239 ? 4.866   -20.153 -10.682 1   31.78  ? 235 ASP A N   1 
ATOM   1916 C  CA  . ASP A 1 239 ? 6.088   -20.722 -10.129 1   29.39  ? 235 ASP A CA  1 
ATOM   1917 C  C   . ASP A 1 239 ? 6.272   -22.209 -10.426 1   30.18  ? 235 ASP A C   1 
ATOM   1918 O  O   . ASP A 1 239 ? 7.112   -22.865 -9.809  1   31.34  ? 235 ASP A O   1 
ATOM   1919 C  CB  . ASP A 1 239 ? 6.141   -20.474 -8.618  1   28.27  ? 235 ASP A CB  1 
ATOM   1920 C  CG  . ASP A 1 239 ? 6.085   -19.012 -8.255  1   27.31  ? 235 ASP A CG  1 
ATOM   1921 O  OD1 . ASP A 1 239 ? 6.822   -18.242 -8.838  1   34.65  ? 235 ASP A OD1 1 
ATOM   1922 O  OD2 . ASP A 1 239 ? 5.318   -18.658 -7.381  1   32.46  ? 235 ASP A OD2 1 
ATOM   1923 N  N   . TYR A 1 240 ? 5.546   -22.726 -11.424 1   30.59  ? 236 TYR A N   1 
ATOM   1924 C  CA  . TYR A 1 240 ? 5.895   -24.012 -12.009 1   34.6   ? 236 TYR A CA  1 
ATOM   1925 C  C   . TYR A 1 240 ? 7.164   -23.845 -12.844 1   31.66  ? 236 TYR A C   1 
ATOM   1926 O  O   . TYR A 1 240 ? 7.329   -22.846 -13.536 1   31.32  ? 236 TYR A O   1 
ATOM   1927 C  CB  . TYR A 1 240 ? 4.734   -24.609 -12.852 1   39.72  ? 236 TYR A CB  1 
ATOM   1928 C  CG  . TYR A 1 240 ? 5.116   -25.872 -13.595 1   40.02  ? 236 TYR A CG  1 
ATOM   1929 C  CD1 . TYR A 1 240 ? 5.151   -27.105 -12.952 1   43.49  ? 236 TYR A CD1 1 
ATOM   1930 C  CD2 . TYR A 1 240 ? 5.532   -25.819 -14.916 1   45.25  ? 236 TYR A CD2 1 
ATOM   1931 C  CE1 . TYR A 1 240 ? 5.546   -28.26  -13.625 1   48.27  ? 236 TYR A CE1 1 
ATOM   1932 C  CE2 . TYR A 1 240 ? 5.923   -26.965 -15.6   1   47.98  ? 236 TYR A CE2 1 
ATOM   1933 C  CZ  . TYR A 1 240 ? 5.929   -28.184 -14.953 1   49.93  ? 236 TYR A CZ  1 
ATOM   1934 O  OH  . TYR A 1 240 ? 6.315   -29.303 -15.654 1   53.38  ? 236 TYR A OH  1 
ATOM   1935 N  N   . LYS A 1 241 ? 8.06    -24.837 -12.756 1   32.49  ? 237 LYS A N   1 
ATOM   1936 C  CA  . LYS A 1 241 ? 9.284   -24.869 -13.541 1   33.29  ? 237 LYS A CA  1 
ATOM   1937 C  C   . LYS A 1 241 ? 9.328   -26.158 -14.358 1   32.79  ? 237 LYS A C   1 
ATOM   1938 O  O   . LYS A 1 241 ? 9.104   -27.241 -13.816 1   31.88  ? 237 LYS A O   1 
ATOM   1939 C  CB  . LYS A 1 241 ? 10.524  -24.788 -12.63  1   35.1   ? 237 LYS A CB  1 
ATOM   1940 C  CG  . LYS A 1 241 ? 10.595  -23.561 -11.729 1   38.57  ? 237 LYS A CG  1 
ATOM   1941 C  CD  . LYS A 1 241 ? 10.794  -22.28  -12.509 1   47.01  ? 237 LYS A CD  1 
ATOM   1942 C  CE  . LYS A 1 241 ? 10.948  -21.066 -11.609 1   56.16  ? 237 LYS A CE  1 
ATOM   1943 N  NZ  . LYS A 1 241 ? 12.231  -21.116 -10.835 1   61.47  ? 237 LYS A NZ  1 
ATOM   1944 N  N   . PRO A 1 242 ? 9.621   -26.091 -15.68  1   29.68  ? 238 PRO A N   1 
ATOM   1945 C  CA  . PRO A 1 242 ? 9.866   -27.301 -16.472 1   29.88  ? 238 PRO A CA  1 
ATOM   1946 C  C   . PRO A 1 242 ? 10.948  -28.232 -15.915 1   27.59  ? 238 PRO A C   1 
ATOM   1947 O  O   . PRO A 1 242 ? 10.89   -29.439 -16.129 1   24.62  ? 238 PRO A O   1 
ATOM   1948 C  CB  . PRO A 1 242 ? 10.298  -26.755 -17.854 1   30.52  ? 238 PRO A CB  1 
ATOM   1949 C  CG  . PRO A 1 242 ? 9.907   -25.303 -17.878 1   30.33  ? 238 PRO A CG  1 
ATOM   1950 C  CD  . PRO A 1 242 ? 9.719   -24.844 -16.459 1   29.27  ? 238 PRO A CD  1 
ATOM   1951 N  N   . SER A 1 243 ? 11.944  -27.662 -15.22  1   25.44  ? 239 SER A N   1 
ATOM   1952 C  CA  . SER A 1 243 ? 13.014  -28.428 -14.602 1   25.03  ? 239 SER A CA  1 
ATOM   1953 C  C   . SER A 1 243 ? 12.636  -29.253 -13.363 1   21.64  ? 239 SER A C   1 
ATOM   1954 O  O   . SER A 1 243 ? 13.438  -30.041 -12.888 1   19.31  ? 239 SER A O   1 
ATOM   1955 C  CB  . SER A 1 243 ? 14.156  -27.484 -14.233 1   26.43  ? 239 SER A CB  1 
ATOM   1956 O  OG  . SER A 1 243 ? 13.732  -26.612 -13.199 1   29.3   ? 239 SER A OG  1 
ATOM   1957 N  N   . PHE A 1 244 ? 11.43   -29.075 -12.817 1   21.67  ? 240 PHE A N   1 
ATOM   1958 C  CA  . PHE A 1 244 ? 10.968  -29.906 -11.713 1   23.69  ? 240 PHE A CA  1 
ATOM   1959 C  C   . PHE A 1 244 ? 11.23   -31.39  -11.945 1   22.28  ? 240 PHE A C   1 
ATOM   1960 O  O   . PHE A 1 244 ? 10.862  -31.906 -12.993 1   22.03  ? 240 PHE A O   1 
ATOM   1961 C  CB  . PHE A 1 244 ? 9.46    -29.745 -11.509 1   23.28  ? 240 PHE A CB  1 
ATOM   1962 C  CG  . PHE A 1 244 ? 9.003   -28.522 -10.754 1   26.86  ? 240 PHE A CG  1 
ATOM   1963 C  CD1 . PHE A 1 244 ? 9.91    -27.693 -10.113 1   28.59  ? 240 PHE A CD1 1 
ATOM   1964 C  CD2 . PHE A 1 244 ? 7.658   -28.208 -10.669 1   27.83  ? 240 PHE A CD2 1 
ATOM   1965 C  CE1 . PHE A 1 244 ? 9.475   -26.586 -9.398  1   30.28  ? 240 PHE A CE1 1 
ATOM   1966 C  CE2 . PHE A 1 244 ? 7.232   -27.109 -9.955  1   29.49  ? 240 PHE A CE2 1 
ATOM   1967 C  CZ  . PHE A 1 244 ? 8.142   -26.29  -9.34   1   28.18  ? 240 PHE A CZ  1 
ATOM   1968 N  N   . PRO A 1 245 ? 11.829  -32.137 -10.99  1   23.85  ? 241 PRO A N   1 
ATOM   1969 C  CA  . PRO A 1 245 ? 11.976  -33.585 -11.164 1   26.7   ? 241 PRO A CA  1 
ATOM   1970 C  C   . PRO A 1 245 ? 10.624  -34.278 -11.341 1   27.4   ? 241 PRO A C   1 
ATOM   1971 O  O   . PRO A 1 245 ? 9.606   -33.839 -10.794 1   25.66  ? 241 PRO A O   1 
ATOM   1972 C  CB  . PRO A 1 245 ? 12.721  -34.029 -9.897  1   26.91  ? 241 PRO A CB  1 
ATOM   1973 C  CG  . PRO A 1 245 ? 13.408  -32.761 -9.394  1   26.57  ? 241 PRO A CG  1 
ATOM   1974 C  CD  . PRO A 1 245 ? 12.437  -31.648 -9.739  1   26.37  ? 241 PRO A CD  1 
ATOM   1975 N  N   . LYS A 1 246 ? 10.626  -35.342 -12.153 1   29.93  ? 242 LYS A N   1 
ATOM   1976 C  CA  . LYS A 1 246 ? 9.401   -36.038 -12.515 1   33.83  ? 242 LYS A CA  1 
ATOM   1977 C  C   . LYS A 1 246 ? 9.338   -37.328 -11.709 1   30.41  ? 242 LYS A C   1 
ATOM   1978 O  O   . LYS A 1 246 ? 9.809   -38.358 -12.173 1   32.71  ? 242 LYS A O   1 
ATOM   1979 C  CB  . LYS A 1 246 ? 9.301   -36.311 -14.042 1   37.49  ? 242 LYS A CB  1 
ATOM   1980 C  CG  . LYS A 1 246 ? 8.959   -35.051 -14.843 1   42.72  ? 242 LYS A CG  1 
ATOM   1981 C  CD  . LYS A 1 246 ? 8.61    -35.344 -16.313 1   48.99  ? 242 LYS A CD  1 
ATOM   1982 C  CE  . LYS A 1 246 ? 8.804   -34.151 -17.232 1   52.07  ? 242 LYS A CE  1 
ATOM   1983 N  NZ  . LYS A 1 246 ? 8.24    -32.901 -16.653 1   54.29  ? 242 LYS A NZ  1 
ATOM   1984 N  N   . TRP A 1 247 ? 8.743   -37.257 -10.509 1   26.88  ? 243 TRP A N   1 
ATOM   1985 C  CA  . TRP A 1 247 ? 8.633   -38.414 -9.633  1   24.53  ? 243 TRP A CA  1 
ATOM   1986 C  C   . TRP A 1 247 ? 7.374   -39.204 -9.978  1   23.98  ? 243 TRP A C   1 
ATOM   1987 O  O   . TRP A 1 247 ? 6.328   -38.62  -10.256 1   23.79  ? 243 TRP A O   1 
ATOM   1988 C  CB  . TRP A 1 247 ? 8.638   -37.989 -8.147  1   21.97  ? 243 TRP A CB  1 
ATOM   1989 C  CG  . TRP A 1 247 ? 9.986   -37.612 -7.599  1   21.59  ? 243 TRP A CG  1 
ATOM   1990 C  CD1 . TRP A 1 247 ? 11.021  -38.458 -7.307  1   21.75  ? 243 TRP A CD1 1 
ATOM   1991 C  CD2 . TRP A 1 247 ? 10.453  -36.288 -7.287  1   19.55  ? 243 TRP A CD2 1 
ATOM   1992 N  NE1 . TRP A 1 247 ? 12.103  -37.74  -6.832  1   19.14  ? 243 TRP A NE1 1 
ATOM   1993 C  CE2 . TRP A 1 247 ? 11.776  -36.409 -6.805  1   19.33  ? 243 TRP A CE2 1 
ATOM   1994 C  CE3 . TRP A 1 247 ? 9.88    -35.015 -7.356  1   19.05  ? 243 TRP A CE3 1 
ATOM   1995 C  CZ2 . TRP A 1 247 ? 12.521  -35.3   -6.385  1   19.45  ? 243 TRP A CZ2 1 
ATOM   1996 C  CZ3 . TRP A 1 247 ? 10.621  -33.915 -6.95   1   19.79  ? 243 TRP A CZ3 1 
ATOM   1997 C  CH2 . TRP A 1 247 ? 11.93   -34.063 -6.479  1   19.83  ? 243 TRP A CH2 1 
ATOM   1998 N  N   . ALA A 1 248 ? 7.477   -40.535 -9.972  1   25.7   ? 244 ALA A N   1 
ATOM   1999 C  CA  . ALA A 1 248 ? 6.313   -41.382 -10.203 1   26.4   ? 244 ALA A CA  1 
ATOM   2000 C  C   . ALA A 1 248 ? 5.4     -41.389 -8.976  1   27.23  ? 244 ALA A C   1 
ATOM   2001 O  O   . ALA A 1 248 ? 5.873   -41.346 -7.85   1   30.67  ? 244 ALA A O   1 
ATOM   2002 C  CB  . ALA A 1 248 ? 6.737   -42.794 -10.546 1   25.07  ? 244 ALA A CB  1 
ATOM   2003 N  N   . ARG A 1 249 ? 4.086   -41.391 -9.206  1   30.18  ? 245 ARG A N   1 
ATOM   2004 C  CA  . ARG A 1 249 ? 3.11    -41.514 -8.139  1   33.36  ? 245 ARG A CA  1 
ATOM   2005 C  C   . ARG A 1 249 ? 3.243   -42.892 -7.497  1   35.96  ? 245 ARG A C   1 
ATOM   2006 O  O   . ARG A 1 249 ? 3.228   -43.9   -8.19   1   34.49  ? 245 ARG A O   1 
ATOM   2007 C  CB  . ARG A 1 249 ? 1.699   -41.327 -8.7    1   33.2   ? 245 ARG A CB  1 
ATOM   2008 C  CG  . ARG A 1 249 ? 0.613   -41.46  -7.67   1   33.77  ? 245 ARG A CG  1 
ATOM   2009 C  CD  . ARG A 1 249 ? -0.746  -41.145 -8.247  1   34.76  ? 245 ARG A CD  1 
ATOM   2010 N  NE  . ARG A 1 249 ? -1.789  -41.204 -7.225  1   39.39  ? 245 ARG A NE  1 
ATOM   2011 C  CZ  . ARG A 1 249 ? -2.157  -40.194 -6.442  1   42.91  ? 245 ARG A CZ  1 
ATOM   2012 N  NH1 . ARG A 1 249 ? -1.522  -39.03  -6.464  1   40.04  ? 245 ARG A NH1 1 
ATOM   2013 N  NH2 . ARG A 1 249 ? -3.194  -40.358 -5.62   1   43.82  ? 245 ARG A NH2 1 
ATOM   2014 N  N   . GLN A 1 250 ? 3.36    -42.946 -6.169  1   41.36  ? 246 GLN A N   1 
ATOM   2015 C  CA  . GLN A 1 250 ? 3.481   -44.24  -5.517  1   45.86  ? 246 GLN A CA  1 
ATOM   2016 C  C   . GLN A 1 250 ? 2.075   -44.726 -5.177  1   48.63  ? 246 GLN A C   1 
ATOM   2017 O  O   . GLN A 1 250 ? 1.144   -43.931 -5.065  1   42.45  ? 246 GLN A O   1 
ATOM   2018 C  CB  . GLN A 1 250 ? 4.387   -44.179 -4.28   1   46.22  ? 246 GLN A CB  1 
ATOM   2019 C  CG  . GLN A 1 250 ? 3.81    -43.442 -3.112  1   45.15  ? 246 GLN A CG  1 
ATOM   2020 C  CD  . GLN A 1 250 ? 4.844   -43.335 -2.027  1   48.38  ? 246 GLN A CD  1 
ATOM   2021 O  OE1 . GLN A 1 250 ? 5.617   -44.259 -1.775  1   57.58  ? 246 GLN A OE1 1 
ATOM   2022 N  NE2 . GLN A 1 250 ? 4.906   -42.204 -1.37   1   49.73  ? 246 GLN A NE2 1 
ATOM   2023 N  N   . ASP A 1 251 ? 1.945   -46.046 -5.025  1   51.62  ? 247 ASP A N   1 
ATOM   2024 C  CA  . ASP A 1 251 ? 0.726   -46.67  -4.536  1   51.92  ? 247 ASP A CA  1 
ATOM   2025 C  C   . ASP A 1 251 ? 0.27    -45.975 -3.253  1   41.64  ? 247 ASP A C   1 
ATOM   2026 O  O   . ASP A 1 251 ? 1.039   -45.803 -2.313  1   41.59  ? 247 ASP A O   1 
ATOM   2027 C  CB  . ASP A 1 251 ? 0.976   -48.176 -4.276  1   62.13  ? 247 ASP A CB  1 
ATOM   2028 C  CG  . ASP A 1 251 ? -0.257  -49.052 -4.359  1   75.88  ? 247 ASP A CG  1 
ATOM   2029 O  OD1 . ASP A 1 251 ? -0.712  -49.311 -5.479  1   87.34  ? 247 ASP A OD1 1 
ATOM   2030 O  OD2 . ASP A 1 251 ? -0.775  -49.468 -3.287  1   79.12  ? 247 ASP A OD2 1 
ATOM   2031 N  N   . PHE A 1 252 ? -0.99   -45.553 -3.228  1   38.56  ? 248 PHE A N   1 
ATOM   2032 C  CA  . PHE A 1 252 ? -1.527  -44.77  -2.133  1   32.96  ? 248 PHE A CA  1 
ATOM   2033 C  C   . PHE A 1 252 ? -1.616  -45.54  -0.812  1   29.8   ? 248 PHE A C   1 
ATOM   2034 O  O   . PHE A 1 252 ? -1.667  -44.952 0.265   1   35.62  ? 248 PHE A O   1 
ATOM   2035 C  CB  . PHE A 1 252 ? -2.911  -44.274 -2.554  1   36.14  ? 248 PHE A CB  1 
ATOM   2036 C  CG  . PHE A 1 252 ? -3.179  -42.939 -1.954  1   35.44  ? 248 PHE A CG  1 
ATOM   2037 C  CD1 . PHE A 1 252 ? -2.644  -41.795 -2.516  1   35.86  ? 248 PHE A CD1 1 
ATOM   2038 C  CD2 . PHE A 1 252 ? -3.872  -42.827 -0.783  1   32.98  ? 248 PHE A CD2 1 
ATOM   2039 C  CE1 . PHE A 1 252 ? -2.861  -40.556 -1.949  1   34.47  ? 248 PHE A CE1 1 
ATOM   2040 C  CE2 . PHE A 1 252 ? -4.077  -41.588 -0.215  1   37.22  ? 248 PHE A CE2 1 
ATOM   2041 C  CZ  . PHE A 1 252 ? -3.566  -40.456 -0.806  1   34.31  ? 248 PHE A CZ  1 
ATOM   2042 N  N   . SER A 1 253 ? -1.671  -46.876 -0.909  1   27.7   ? 249 SER A N   1 
ATOM   2043 C  CA  . SER A 1 253 ? -1.619  -47.752 0.247   1   25.16  ? 249 SER A CA  1 
ATOM   2044 C  C   . SER A 1 253 ? -0.262  -47.772 0.949   1   28.42  ? 249 SER A C   1 
ATOM   2045 O  O   . SER A 1 253 ? -0.13   -48.281 2.059   1   30.07  ? 249 SER A O   1 
ATOM   2046 C  CB  . SER A 1 253 ? -1.997  -49.17  -0.163  1   23.66  ? 249 SER A CB  1 
ATOM   2047 O  OG  . SER A 1 253 ? -0.96   -49.783 -0.916  1   25.31  ? 249 SER A OG  1 
ATOM   2048 N  N   . LYS A 1 254 ? 0.773   -47.254 0.283   1   31.48  ? 250 LYS A N   1 
ATOM   2049 C  CA  . LYS A 1 254 ? 2.081   -47.097 0.896   1   32.69  ? 250 LYS A CA  1 
ATOM   2050 C  C   . LYS A 1 254 ? 2.233   -45.723 1.55    1   32.68  ? 250 LYS A C   1 
ATOM   2051 O  O   . LYS A 1 254 ? 3.124   -45.54  2.368   1   33.83  ? 250 LYS A O   1 
ATOM   2052 C  CB  . LYS A 1 254 ? 3.166   -47.317 -0.165  1   31.12  ? 250 LYS A CB  1 
ATOM   2053 C  CG  . LYS A 1 254 ? 3.146   -48.69  -0.824  1   31.02  ? 250 LYS A CG  1 
ATOM   2054 C  CD  . LYS A 1 254 ? 3.715   -49.794 0.091   1   33.44  ? 250 LYS A CD  1 
ATOM   2055 C  CE  . LYS A 1 254 ? 3.462   -51.189 -0.439  1   36.07  ? 250 LYS A CE  1 
ATOM   2056 N  NZ  . LYS A 1 254 ? 2       -51.52  -0.439  1   40.17  ? 250 LYS A NZ  1 
ATOM   2057 N  N   . VAL A 1 255 ? 1.35    -44.774 1.212   1   35.53  ? 251 VAL A N   1 
ATOM   2058 C  CA  . VAL A 1 255 ? 1.37    -43.441 1.794   1   35.21  ? 251 VAL A CA  1 
ATOM   2059 C  C   . VAL A 1 255 ? 0.959   -43.45  3.266   1   33.64  ? 251 VAL A C   1 
ATOM   2060 O  O   . VAL A 1 255 ? 1.61    -42.819 4.094   1   34.74  ? 251 VAL A O   1 
ATOM   2061 C  CB  . VAL A 1 255 ? 0.479   -42.481 0.995   1   33.3   ? 251 VAL A CB  1 
ATOM   2062 C  CG1 . VAL A 1 255 ? 0.364   -41.125 1.693   1   34.97  ? 251 VAL A CG1 1 
ATOM   2063 C  CG2 . VAL A 1 255 ? 0.995   -42.321 -0.423  1   34.76  ? 251 VAL A CG2 1 
ATOM   2064 N  N   . VAL A 1 256 ? -0.136  -44.152 3.565   1   30.6   ? 252 VAL A N   1 
ATOM   2065 C  CA  . VAL A 1 256 ? -0.58   -44.381 4.932   1   29.56  ? 252 VAL A CA  1 
ATOM   2066 C  C   . VAL A 1 256 ? -0.941  -45.858 5.06    1   26.44  ? 252 VAL A C   1 
ATOM   2067 O  O   . VAL A 1 256 ? -2.115  -46.225 5.045   1   23.59  ? 252 VAL A O   1 
ATOM   2068 C  CB  . VAL A 1 256 ? -1.742  -43.454 5.37    1   34.12  ? 252 VAL A CB  1 
ATOM   2069 C  CG1 . VAL A 1 256 ? -2.074  -43.649 6.859   1   36.14  ? 252 VAL A CG1 1 
ATOM   2070 C  CG2 . VAL A 1 256 ? -1.402  -41.991 5.083   1   34.18  ? 252 VAL A CG2 1 
ATOM   2071 N  N   . PRO A 1 257 ? 0.074   -46.744 5.219   1   23.83  ? 253 PRO A N   1 
ATOM   2072 C  CA  . PRO A 1 257 ? -0.149  -48.193 5.265   1   23.42  ? 253 PRO A CA  1 
ATOM   2073 C  C   . PRO A 1 257 ? -1.272  -48.712 6.162   1   25.15  ? 253 PRO A C   1 
ATOM   2074 O  O   . PRO A 1 257 ? -2.003  -49.595 5.744   1   26.22  ? 253 PRO A O   1 
ATOM   2075 C  CB  . PRO A 1 257 ? 1.214   -48.724 5.718   1   23.33  ? 253 PRO A CB  1 
ATOM   2076 C  CG  . PRO A 1 257 ? 2.2     -47.675 5.254   1   22.94  ? 253 PRO A CG  1 
ATOM   2077 C  CD  . PRO A 1 257 ? 1.496   -46.377 5.368   1   22.09  ? 253 PRO A CD  1 
ATOM   2078 N  N   . PRO A 1 258 ? -1.473  -48.218 7.408   1   28.48  ? 254 PRO A N   1 
ATOM   2079 C  CA  . PRO A 1 258 ? -2.522  -48.756 8.281   1   29.73  ? 254 PRO A CA  1 
ATOM   2080 C  C   . PRO A 1 258 ? -3.958  -48.468 7.842   1   34.3   ? 254 PRO A C   1 
ATOM   2081 O  O   . PRO A 1 258 ? -4.9    -48.99  8.429   1   40.1   ? 254 PRO A O   1 
ATOM   2082 C  CB  . PRO A 1 258 ? -2.255  -48.064 9.624   1   31.28  ? 254 PRO A CB  1 
ATOM   2083 C  CG  . PRO A 1 258 ? -0.92   -47.432 9.513   1   29.45  ? 254 PRO A CG  1 
ATOM   2084 C  CD  . PRO A 1 258 ? -0.7    -47.15  8.06    1   29.72  ? 254 PRO A CD  1 
ATOM   2085 N  N   . LEU A 1 259 ? -4.116  -47.616 6.826   1   34.1   ? 255 LEU A N   1 
ATOM   2086 C  CA  . LEU A 1 259 ? -5.412  -47.094 6.428   1   31.06  ? 255 LEU A CA  1 
ATOM   2087 C  C   . LEU A 1 259 ? -6.159  -48.069 5.517   1   30.61  ? 255 LEU A C   1 
ATOM   2088 O  O   . LEU A 1 259 ? -5.567  -48.652 4.611   1   25.02  ? 255 LEU A O   1 
ATOM   2089 C  CB  . LEU A 1 259 ? -5.167  -45.769 5.708   1   31.03  ? 255 LEU A CB  1 
ATOM   2090 C  CG  . LEU A 1 259 ? -6.278  -44.768 5.685   1   32.11  ? 255 LEU A CG  1 
ATOM   2091 C  CD1 . LEU A 1 259 ? -6.798  -44.465 7.059   1   31     ? 255 LEU A CD1 1 
ATOM   2092 C  CD2 . LEU A 1 259 ? -5.799  -43.499 5.05    1   33.59  ? 255 LEU A CD2 1 
ATOM   2093 N  N   . ASP A 1 260 ? -7.46   -48.249 5.783   1   32.64  ? 256 ASP A N   1 
ATOM   2094 C  CA  . ASP A 1 260 ? -8.301  -49.165 5.023   1   37.65  ? 256 ASP A CA  1 
ATOM   2095 C  C   . ASP A 1 260 ? -8.691  -48.583 3.659   1   32.98  ? 256 ASP A C   1 
ATOM   2096 O  O   . ASP A 1 260 ? -8.379  -47.441 3.35    1   30.48  ? 256 ASP A O   1 
ATOM   2097 C  CB  . ASP A 1 260 ? -9.562  -49.537 5.853   1   43.12  ? 256 ASP A CB  1 
ATOM   2098 C  CG  . ASP A 1 260 ? -10.473 -48.362 6.254   1   47.51  ? 256 ASP A CG  1 
ATOM   2099 O  OD1 . ASP A 1 260 ? -10.014 -47.474 7.028   1   55.18  ? 256 ASP A OD1 1 
ATOM   2100 O  OD2 . ASP A 1 260 ? -11.634 -48.329 5.8     1   51.75  ? 256 ASP A OD2 1 
ATOM   2101 N  N   . GLU A 1 261 ? -9.385  -49.378 2.847   1   31.96  ? 257 GLU A N   1 
ATOM   2102 C  CA  . GLU A 1 261 ? -9.766  -48.96  1.508   1   37.05  ? 257 GLU A CA  1 
ATOM   2103 C  C   . GLU A 1 261 ? -10.607 -47.679 1.471   1   35.48  ? 257 GLU A C   1 
ATOM   2104 O  O   . GLU A 1 261 ? -10.386 -46.813 0.622   1   33.69  ? 257 GLU A O   1 
ATOM   2105 C  CB  . GLU A 1 261 ? -10.507 -50.116 0.834   1   36.63  ? 257 GLU A CB  1 
ATOM   2106 C  CG  . GLU A 1 261 ? -10.859 -49.892 -0.622  1   39.69  ? 257 GLU A CG  1 
ATOM   2107 C  CD  . GLU A 1 261 ? -11.546 -51.111 -1.209  1   44.48  ? 257 GLU A CD  1 
ATOM   2108 O  OE1 . GLU A 1 261 ? -10.838 -52.105 -1.494  1   51.46  ? 257 GLU A OE1 1 
ATOM   2109 O  OE2 . GLU A 1 261 ? -12.793 -51.102 -1.317  1   44.4   ? 257 GLU A OE2 1 
ATOM   2110 N  N   . ASP A 1 262 ? -11.563 -47.561 2.401   1   30.22  ? 258 ASP A N   1 
ATOM   2111 C  CA  . ASP A 1 262 ? -12.415 -46.385 2.474   1   29.27  ? 258 ASP A CA  1 
ATOM   2112 C  C   . ASP A 1 262 ? -11.62  -45.146 2.871   1   27.33  ? 258 ASP A C   1 
ATOM   2113 O  O   . ASP A 1 262 ? -11.795 -44.079 2.292   1   25.56  ? 258 ASP A O   1 
ATOM   2114 C  CB  . ASP A 1 262 ? -13.587 -46.617 3.449   1   29.15  ? 258 ASP A CB  1 
ATOM   2115 C  CG  . ASP A 1 262 ? -14.738 -47.458 2.868   1   30.85  ? 258 ASP A CG  1 
ATOM   2116 O  OD1 . ASP A 1 262 ? -14.824 -47.579 1.621   1   31.28  ? 258 ASP A OD1 1 
ATOM   2117 O  OD2 . ASP A 1 262 ? -15.531 -48.013 3.662   1   33.3   ? 258 ASP A OD2 1 
ATOM   2118 N  N   . GLY A 1 263 ? -10.756 -45.299 3.875   1   27.3   ? 259 GLY A N   1 
ATOM   2119 C  CA  . GLY A 1 263 ? -9.895  -44.221 4.325   1   28.38  ? 259 GLY A CA  1 
ATOM   2120 C  C   . GLY A 1 263 ? -8.989  -43.718 3.206   1   27.47  ? 259 GLY A C   1 
ATOM   2121 O  O   . GLY A 1 263 ? -8.869  -42.509 3.015   1   25.51  ? 259 GLY A O   1 
ATOM   2122 N  N   . ARG A 1 264 ? -8.38   -44.666 2.473   1   26.17  ? 260 ARG A N   1 
ATOM   2123 C  CA  . ARG A 1 264 ? -7.481  -44.345 1.378   1   28.33  ? 260 ARG A CA  1 
ATOM   2124 C  C   . ARG A 1 264 ? -8.223  -43.558 0.312   1   25.41  ? 260 ARG A C   1 
ATOM   2125 O  O   . ARG A 1 264 ? -7.712  -42.573 -0.202  1   24.3   ? 260 ARG A O   1 
ATOM   2126 C  CB  . ARG A 1 264 ? -6.849  -45.597 0.74    1   28.44  ? 260 ARG A CB  1 
ATOM   2127 C  CG  . ARG A 1 264 ? -5.853  -46.282 1.679   1   33.33  ? 260 ARG A CG  1 
ATOM   2128 C  CD  . ARG A 1 264 ? -4.878  -47.228 0.963   1   32.4   ? 260 ARG A CD  1 
ATOM   2129 N  NE  . ARG A 1 264 ? -5.544  -48.266 0.183   1   32.61  ? 260 ARG A NE  1 
ATOM   2130 C  CZ  . ARG A 1 264 ? -6.048  -49.392 0.68    1   32.13  ? 260 ARG A CZ  1 
ATOM   2131 N  NH1 . ARG A 1 264 ? -5.828  -49.76  1.931   1   33.6   ? 260 ARG A NH1 1 
ATOM   2132 N  NH2 . ARG A 1 264 ? -6.767  -50.18  -0.109  1   32.15  ? 260 ARG A NH2 1 
ATOM   2133 N  N   . SER A 1 265 ? -9.423  -44.031 -0.012  1   25.77  ? 261 SER A N   1 
ATOM   2134 C  CA  . SER A 1 265 ? -10.269 -43.389 -0.996  1   27.37  ? 261 SER A CA  1 
ATOM   2135 C  C   . SER A 1 265 ? -10.524 -41.931 -0.615  1   28.69  ? 261 SER A C   1 
ATOM   2136 O  O   . SER A 1 265 ? -10.296 -41.03  -1.421  1   28.43  ? 261 SER A O   1 
ATOM   2137 C  CB  . SER A 1 265 ? -11.56  -44.183 -1.129  1   27.36  ? 261 SER A CB  1 
ATOM   2138 O  OG  . SER A 1 265 ? -12.519 -43.472 -1.882  1   30.31  ? 261 SER A OG  1 
ATOM   2139 N  N   . LEU A 1 266 ? -10.978 -41.708 0.626   1   26.97  ? 262 LEU A N   1 
ATOM   2140 C  CA  . LEU A 1 266 ? -11.285 -40.361 1.071   1   28.94  ? 262 LEU A CA  1 
ATOM   2141 C  C   . LEU A 1 266 ? -10.02  -39.5   1.106   1   30.61  ? 262 LEU A C   1 
ATOM   2142 O  O   . LEU A 1 266 ? -10.021 -38.361 0.622   1   31.46  ? 262 LEU A O   1 
ATOM   2143 C  CB  . LEU A 1 266 ? -12.001 -40.403 2.441   1   29.33  ? 262 LEU A CB  1 
ATOM   2144 C  CG  . LEU A 1 266 ? -12.172 -39.063 3.153   1   29.12  ? 262 LEU A CG  1 
ATOM   2145 C  CD1 . LEU A 1 266 ? -13.007 -38.077 2.325   1   28.8   ? 262 LEU A CD1 1 
ATOM   2146 C  CD2 . LEU A 1 266 ? -12.791 -39.262 4.498   1   32.12  ? 262 LEU A CD2 1 
ATOM   2147 N  N   . LEU A 1 267 ? -8.93   -40.057 1.647   1   27.67  ? 263 LEU A N   1 
ATOM   2148 C  CA  . LEU A 1 267 ? -7.68   -39.313 1.712   1   28.71  ? 263 LEU A CA  1 
ATOM   2149 C  C   . LEU A 1 267 ? -7.199  -38.869 0.328   1   29.37  ? 263 LEU A C   1 
ATOM   2150 O  O   . LEU A 1 267 ? -6.813  -37.713 0.159   1   30.02  ? 263 LEU A O   1 
ATOM   2151 C  CB  . LEU A 1 267 ? -6.587  -40.118 2.411   1   28.75  ? 263 LEU A CB  1 
ATOM   2152 C  CG  . LEU A 1 267 ? -5.231  -39.396 2.528   1   27.91  ? 263 LEU A CG  1 
ATOM   2153 C  CD1 . LEU A 1 267 ? -5.366  -38.129 3.333   1   28.76  ? 263 LEU A CD1 1 
ATOM   2154 C  CD2 . LEU A 1 267 ? -4.176  -40.261 3.161   1   28.66  ? 263 LEU A CD2 1 
ATOM   2155 N  N   . SER A 1 268 ? -7.239  -39.773 -0.658  1   25.31  ? 264 SER A N   1 
ATOM   2156 C  CA  . SER A 1 268 ? -6.794  -39.439 -2.002  1   29.9   ? 264 SER A CA  1 
ATOM   2157 C  C   . SER A 1 268 ? -7.639  -38.318 -2.611  1   31.21  ? 264 SER A C   1 
ATOM   2158 O  O   . SER A 1 268 ? -7.106  -37.426 -3.268  1   38.73  ? 264 SER A O   1 
ATOM   2159 C  CB  . SER A 1 268 ? -6.773  -40.663 -2.925  1   28.12  ? 264 SER A CB  1 
ATOM   2160 O  OG  . SER A 1 268 ? -8.059  -41.231 -3.086  1   28.83  ? 264 SER A OG  1 
ATOM   2161 N  N   . GLN A 1 269 ? -8.946  -38.327 -2.338  1   29.03  ? 265 GLN A N   1 
ATOM   2162 C  CA  . GLN A 1 269 ? -9.821  -37.289 -2.85   1   28.85  ? 265 GLN A CA  1 
ATOM   2163 C  C   . GLN A 1 269 ? -9.595  -35.937 -2.181  1   27.83  ? 265 GLN A C   1 
ATOM   2164 O  O   . GLN A 1 269 ? -9.829  -34.895 -2.786  1   29.1   ? 265 GLN A O   1 
ATOM   2165 C  CB  . GLN A 1 269 ? -11.274 -37.727 -2.712  1   28.26  ? 265 GLN A CB  1 
ATOM   2166 C  CG  . GLN A 1 269 ? -11.616 -38.92  -3.634  1   27.94  ? 265 GLN A CG  1 
ATOM   2167 C  CD  . GLN A 1 269 ? -13.052 -39.351 -3.446  1   30.3   ? 265 GLN A CD  1 
ATOM   2168 O  OE1 . GLN A 1 269 ? -13.98  -38.595 -3.766  1   32.98  ? 265 GLN A OE1 1 
ATOM   2169 N  NE2 . GLN A 1 269 ? -13.282 -40.541 -2.879  1   29.36  ? 265 GLN A NE2 1 
ATOM   2170 N  N   . MET A 1 270 ? -9.119  -35.951 -0.938  1   27.24  ? 266 MET A N   1 
ATOM   2171 C  CA  . MET A 1 270 ? -8.774  -34.721 -0.247  1   27.88  ? 266 MET A CA  1 
ATOM   2172 C  C   . MET A 1 270 ? -7.445  -34.152 -0.746  1   31.88  ? 266 MET A C   1 
ATOM   2173 O  O   . MET A 1 270 ? -7.244  -32.932 -0.714  1   35.52  ? 266 MET A O   1 
ATOM   2174 C  CB  . MET A 1 270 ? -8.729  -34.965 1.271   1   26.36  ? 266 MET A CB  1 
ATOM   2175 C  CG  . MET A 1 270 ? -10.103 -35.269 1.828   1   25.46  ? 266 MET A CG  1 
ATOM   2176 S  SD  . MET A 1 270 ? -10.094 -35.718 3.587   1   27.75  ? 266 MET A SD  1 
ATOM   2177 C  CE  . MET A 1 270 ? -10.182 -34.054 4.285   1   24.71  ? 266 MET A CE  1 
ATOM   2178 N  N   . LEU A 1 271 ? -6.556  -35.033 -1.223  1   28.77  ? 267 LEU A N   1 
ATOM   2179 C  CA  . LEU A 1 271 ? -5.228  -34.633 -1.663  1   30.03  ? 267 LEU A CA  1 
ATOM   2180 C  C   . LEU A 1 271 ? -5.087  -34.623 -3.188  1   30.34  ? 267 LEU A C   1 
ATOM   2181 O  O   . LEU A 1 271 ? -3.984  -34.734 -3.719  1   26.67  ? 267 LEU A O   1 
ATOM   2182 C  CB  . LEU A 1 271 ? -4.181  -35.572 -1.029  1   29.65  ? 267 LEU A CB  1 
ATOM   2183 C  CG  . LEU A 1 271 ? -4.139  -35.579 0.502   1   30.14  ? 267 LEU A CG  1 
ATOM   2184 C  CD1 . LEU A 1 271 ? -3.09   -36.536 1.033   1   31.12  ? 267 LEU A CD1 1 
ATOM   2185 C  CD2 . LEU A 1 271 ? -3.859  -34.186 1.078   1   31.77  ? 267 LEU A CD2 1 
ATOM   2186 N  N   . HIS A 1 272 ? -6.206  -34.46  -3.896  1   30.91  ? 268 HIS A N   1 
ATOM   2187 C  CA  . HIS A 1 272 ? -6.166  -34.36  -5.346  1   36.46  ? 268 HIS A CA  1 
ATOM   2188 C  C   . HIS A 1 272 ? -5.425  -33.079 -5.732  1   34.18  ? 268 HIS A C   1 
ATOM   2189 O  O   . HIS A 1 272 ? -5.644  -32.033 -5.114  1   33.58  ? 268 HIS A O   1 
ATOM   2190 C  CB  . HIS A 1 272 ? -7.596  -34.386 -5.92   1   42.49  ? 268 HIS A CB  1 
ATOM   2191 C  CG  . HIS A 1 272 ? -7.672  -34.829 -7.349  1   49.18  ? 268 HIS A CG  1 
ATOM   2192 N  ND1 . HIS A 1 272 ? -7.039  -34.118 -8.366  1   55.33  ? 268 HIS A ND1 1 
ATOM   2193 C  CD2 . HIS A 1 272 ? -8.293  -35.903 -7.887  1   50.66  ? 268 HIS A CD2 1 
ATOM   2194 C  CE1 . HIS A 1 272 ? -7.301  -34.775 -9.485  1   55.93  ? 268 HIS A CE1 1 
ATOM   2195 N  NE2 . HIS A 1 272 ? -8.065  -35.855 -9.241  1   50.38  ? 268 HIS A NE2 1 
ATOM   2196 N  N   . TYR A 1 273 ? -4.535  -33.175 -6.731  1   29.88  ? 269 TYR A N   1 
ATOM   2197 C  CA  . TYR A 1 273 ? -3.764  -32.021 -7.173  1   31.47  ? 269 TYR A CA  1 
ATOM   2198 C  C   . TYR A 1 273 ? -4.67   -30.896 -7.665  1   30.36  ? 269 TYR A C   1 
ATOM   2199 O  O   . TYR A 1 273 ? -4.536  -29.756 -7.226  1   31.54  ? 269 TYR A O   1 
ATOM   2200 C  CB  . TYR A 1 273 ? -2.743  -32.371 -8.283  1   28.68  ? 269 TYR A CB  1 
ATOM   2201 C  CG  . TYR A 1 273 ? -1.422  -32.858 -7.732  1   30.2   ? 269 TYR A CG  1 
ATOM   2202 C  CD1 . TYR A 1 273 ? -0.573  -32.001 -7.042  1   32.65  ? 269 TYR A CD1 1 
ATOM   2203 C  CD2 . TYR A 1 273 ? -1.034  -34.178 -7.869  1   29.24  ? 269 TYR A CD2 1 
ATOM   2204 C  CE1 . TYR A 1 273 ? 0.641   -32.444 -6.522  1   31.76  ? 269 TYR A CE1 1 
ATOM   2205 C  CE2 . TYR A 1 273 ? 0.174   -34.63  -7.367  1   29.22  ? 269 TYR A CE2 1 
ATOM   2206 C  CZ  . TYR A 1 273 ? 1.014   -33.762 -6.692  1   30.69  ? 269 TYR A CZ  1 
ATOM   2207 O  OH  . TYR A 1 273 ? 2.208   -34.231 -6.179  1   28.82  ? 269 TYR A OH  1 
ATOM   2208 N  N   . ASP A 1 274 ? -5.591  -31.245 -8.565  1   28.23  ? 270 ASP A N   1 
ATOM   2209 C  CA  . ASP A 1 274 ? -6.458  -30.274 -9.205  1   30.46  ? 270 ASP A CA  1 
ATOM   2210 C  C   . ASP A 1 274 ? -7.45   -29.769 -8.165  1   31.77  ? 270 ASP A C   1 
ATOM   2211 O  O   . ASP A 1 274 ? -8.264  -30.54  -7.657  1   31.67  ? 270 ASP A O   1 
ATOM   2212 C  CB  . ASP A 1 274 ? -7.179  -30.901 -10.409 1   31.45  ? 270 ASP A CB  1 
ATOM   2213 C  CG  . ASP A 1 274 ? -7.997  -29.942 -11.251 1   33.89  ? 270 ASP A CG  1 
ATOM   2214 O  OD1 . ASP A 1 274 ? -8.27   -28.816 -10.773 1   34.19  ? 270 ASP A OD1 1 
ATOM   2215 O  OD2 . ASP A 1 274 ? -8.374  -30.32  -12.395 1   33.67  ? 270 ASP A OD2 1 
ATOM   2216 N  N   . PRO A 1 275 ? -7.415  -28.465 -7.808  1   33.79  ? 271 PRO A N   1 
ATOM   2217 C  CA  . PRO A 1 275 ? -8.34   -27.92  -6.819  1   33.35  ? 271 PRO A CA  1 
ATOM   2218 C  C   . PRO A 1 275 ? -9.8    -28.118 -7.23   1   31.92  ? 271 PRO A C   1 
ATOM   2219 O  O   . PRO A 1 275 ? -10.653 -28.263 -6.362  1   32.28  ? 271 PRO A O   1 
ATOM   2220 C  CB  . PRO A 1 275 ? -7.931  -26.436 -6.74   1   34.66  ? 271 PRO A CB  1 
ATOM   2221 C  CG  . PRO A 1 275 ? -6.573  -26.37  -7.27   1   36.35  ? 271 PRO A CG  1 
ATOM   2222 C  CD  . PRO A 1 275 ? -6.503  -27.438 -8.334  1   36.45  ? 271 PRO A CD  1 
ATOM   2223 N  N   . ASN A 1 276 ? -10.063 -28.16  -8.548  1   30.01  ? 272 ASN A N   1 
ATOM   2224 C  CA  . ASN A 1 276 ? -11.407 -28.387 -9.056  1   32.53  ? 272 ASN A CA  1 
ATOM   2225 C  C   . ASN A 1 276 ? -11.957 -29.797 -8.831  1   31.38  ? 272 ASN A C   1 
ATOM   2226 O  O   . ASN A 1 276 ? -13.169 -29.964 -8.771  1   30.42  ? 272 ASN A O   1 
ATOM   2227 C  CB  . ASN A 1 276 ? -11.506 -28.101 -10.554 1   33.96  ? 272 ASN A CB  1 
ATOM   2228 C  CG  . ASN A 1 276 ? -11.179 -26.693 -10.956 1   38.96  ? 272 ASN A CG  1 
ATOM   2229 O  OD1 . ASN A 1 276 ? -11.499 -25.698 -10.301 1   39.4   ? 272 ASN A OD1 1 
ATOM   2230 N  ND2 . ASN A 1 276 ? -10.504 -26.593 -12.069 1   45.28  ? 272 ASN A ND2 1 
ATOM   2231 N  N   . LYS A 1 277 ? -11.075 -30.8   -8.739  1   31.95  ? 273 LYS A N   1 
ATOM   2232 C  CA  . LYS A 1 277 ? -11.49  -32.18  -8.527  1   33.7   ? 273 LYS A CA  1 
ATOM   2233 C  C   . LYS A 1 277 ? -11.42  -32.589 -7.064  1   31.71  ? 273 LYS A C   1 
ATOM   2234 O  O   . LYS A 1 277 ? -11.962 -33.613 -6.681  1   31.23  ? 273 LYS A O   1 
ATOM   2235 C  CB  . LYS A 1 277 ? -10.6   -33.164 -9.328  1   40.16  ? 273 LYS A CB  1 
ATOM   2236 C  CG  . LYS A 1 277 ? -10.65  -32.983 -10.835 1   47.14  ? 273 LYS A CG  1 
ATOM   2237 C  CD  . LYS A 1 277 ? -12.066 -32.917 -11.386 1   54.23  ? 273 LYS A CD  1 
ATOM   2238 C  CE  . LYS A 1 277 ? -12.103 -32.604 -12.868 1   60.57  ? 273 LYS A CE  1 
ATOM   2239 N  NZ  . LYS A 1 277 ? -13.395 -31.95  -13.237 1   61.96  ? 273 LYS A NZ  1 
ATOM   2240 N  N   . ARG A 1 278 ? -10.689 -31.813 -6.262  1   32.03  ? 274 ARG A N   1 
ATOM   2241 C  CA  . ARG A 1 278 ? -10.534 -32.098 -4.848  1   30.78  ? 274 ARG A CA  1 
ATOM   2242 C  C   . ARG A 1 278 ? -11.926 -32.079 -4.21   1   30.82  ? 274 ARG A C   1 
ATOM   2243 O  O   . ARG A 1 278 ? -12.739 -31.215 -4.536  1   28.77  ? 274 ARG A O   1 
ATOM   2244 C  CB  . ARG A 1 278 ? -9.592  -31.054 -4.237  1   32.29  ? 274 ARG A CB  1 
ATOM   2245 C  CG  . ARG A 1 278 ? -8.92   -31.483 -2.96   1   33.65  ? 274 ARG A CG  1 
ATOM   2246 C  CD  . ARG A 1 278 ? -7.958  -30.421 -2.44   1   33.86  ? 274 ARG A CD  1 
ATOM   2247 N  NE  . ARG A 1 278 ? -6.798  -30.249 -3.307  1   33.19  ? 274 ARG A NE  1 
ATOM   2248 C  CZ  . ARG A 1 278 ? -6.206  -29.084 -3.543  1   31.96  ? 274 ARG A CZ  1 
ATOM   2249 N  NH1 . ARG A 1 278 ? -6.457  -28.023 -2.8    1   29.31  ? 274 ARG A NH1 1 
ATOM   2250 N  NH2 . ARG A 1 278 ? -5.318  -28.99  -4.532  1   32.82  ? 274 ARG A NH2 1 
ATOM   2251 N  N   . ILE A 1 279 ? -12.194 -33.038 -3.314  1   28.63  ? 275 ILE A N   1 
ATOM   2252 C  CA  . ILE A 1 279 ? -13.519 -33.197 -2.737  1   28.39  ? 275 ILE A CA  1 
ATOM   2253 C  C   . ILE A 1 279 ? -13.857 -32.001 -1.845  1   27.16  ? 275 ILE A C   1 
ATOM   2254 O  O   . ILE A 1 279 ? -12.967 -31.441 -1.222  1   28.22  ? 275 ILE A O   1 
ATOM   2255 C  CB  . ILE A 1 279 ? -13.609 -34.551 -1.993  1   27.7   ? 275 ILE A CB  1 
ATOM   2256 C  CG1 . ILE A 1 279 ? -15.07  -34.938 -1.684  1   28.82  ? 275 ILE A CG1 1 
ATOM   2257 C  CG2 . ILE A 1 279 ? -12.784 -34.558 -0.734  1   27.81  ? 275 ILE A CG2 1 
ATOM   2258 C  CD1 . ILE A 1 279 ? -15.274 -36.313 -1.247  1   27.84  ? 275 ILE A CD1 1 
ATOM   2259 N  N   . SER A 1 280 ? -15.131 -31.594 -1.818  1   25.5   ? 276 SER A N   1 
ATOM   2260 C  CA  . SER A 1 280 ? -15.59  -30.568 -0.891  1   26.69  ? 276 SER A CA  1 
ATOM   2261 C  C   . SER A 1 280 ? -15.897 -31.183 0.47    1   26.28  ? 276 SER A C   1 
ATOM   2262 O  O   . SER A 1 280 ? -16.105 -32.39  0.56    1   24.01  ? 276 SER A O   1 
ATOM   2263 C  CB  . SER A 1 280 ? -16.849 -29.888 -1.406  1   27.57  ? 276 SER A CB  1 
ATOM   2264 O  OG  . SER A 1 280 ? -17.928 -30.81  -1.443  1   27.31  ? 276 SER A OG  1 
ATOM   2265 N  N   . ALA A 1 281 ? -15.928 -30.339 1.511   1   28.27  ? 277 ALA A N   1 
ATOM   2266 C  CA  . ALA A 1 281 ? -16.27  -30.788 2.852   1   29.37  ? 277 ALA A CA  1 
ATOM   2267 C  C   . ALA A 1 281 ? -17.678 -31.369 2.883   1   27.83  ? 277 ALA A C   1 
ATOM   2268 O  O   . ALA A 1 281 ? -17.923 -32.432 3.454   1   27.62  ? 277 ALA A O   1 
ATOM   2269 C  CB  . ALA A 1 281 ? -16.157 -29.645 3.842   1   32.68  ? 277 ALA A CB  1 
ATOM   2270 N  N   . LYS A 1 282 ? -18.597 -30.652 2.24    1   29.7   ? 278 LYS A N   1 
ATOM   2271 C  CA  . LYS A 1 282 ? -19.978 -31.082 2.103   1   30.08  ? 278 LYS A CA  1 
ATOM   2272 C  C   . LYS A 1 282 ? -20.078 -32.501 1.532   1   30.32  ? 278 LYS A C   1 
ATOM   2273 O  O   . LYS A 1 282 ? -20.737 -33.358 2.109   1   29.35  ? 278 LYS A O   1 
ATOM   2274 C  CB  . LYS A 1 282 ? -20.67  -30.014 1.244   1   30.66  ? 278 LYS A CB  1 
ATOM   2275 C  CG  . LYS A 1 282 ? -22.115 -30.185 1.039   1   36.98  ? 278 LYS A CG  1 
ATOM   2276 C  CD  . LYS A 1 282 ? -22.741 -29.054 0.231   1   37.84  ? 278 LYS A CD  1 
ATOM   2277 C  CE  . LYS A 1 282 ? -22.857 -27.782 1.021   1   37.38  ? 278 LYS A CE  1 
ATOM   2278 N  NZ  . LYS A 1 282 ? -23.871 -26.884 0.421   1   34.96  ? 278 LYS A NZ  1 
ATOM   2279 N  N   . ALA A 1 283 ? -19.391 -32.761 0.413   1   35.65  ? 279 ALA A N   1 
ATOM   2280 C  CA  . ALA A 1 283 ? -19.445 -34.069 -0.243  1   33.53  ? 279 ALA A CA  1 
ATOM   2281 C  C   . ALA A 1 283 ? -18.75  -35.175 0.553   1   26.96  ? 279 ALA A C   1 
ATOM   2282 O  O   . ALA A 1 283 ? -19.222 -36.311 0.576   1   28.57  ? 279 ALA A O   1 
ATOM   2283 C  CB  . ALA A 1 283 ? -18.843 -33.996 -1.644  1   32.1   ? 279 ALA A CB  1 
ATOM   2284 N  N   . ALA A 1 284 ? -17.637 -34.827 1.205   1   24.03  ? 280 ALA A N   1 
ATOM   2285 C  CA  . ALA A 1 284 ? -16.888 -35.781 2.011   1   25.8   ? 280 ALA A CA  1 
ATOM   2286 C  C   . ALA A 1 284 ? -17.696 -36.318 3.193   1   25.8   ? 280 ALA A C   1 
ATOM   2287 O  O   . ALA A 1 284 ? -17.499 -37.458 3.6     1   27     ? 280 ALA A O   1 
ATOM   2288 C  CB  . ALA A 1 284 ? -15.6   -35.155 2.513   1   26.02  ? 280 ALA A CB  1 
ATOM   2289 N  N   . LEU A 1 285 ? -18.615 -35.503 3.733   1   25.34  ? 281 LEU A N   1 
ATOM   2290 C  CA  . LEU A 1 285 ? -19.476 -35.941 4.823   1   26.24  ? 281 LEU A CA  1 
ATOM   2291 C  C   . LEU A 1 285 ? -20.248 -37.219 4.494   1   28.31  ? 281 LEU A C   1 
ATOM   2292 O  O   . LEU A 1 285 ? -20.569 -37.996 5.392   1   29.86  ? 281 LEU A O   1 
ATOM   2293 C  CB  . LEU A 1 285 ? -20.47  -34.843 5.2     1   25.78  ? 281 LEU A CB  1 
ATOM   2294 C  CG  . LEU A 1 285 ? -19.926 -33.663 5.995   1   26.1   ? 281 LEU A CG  1 
ATOM   2295 C  CD1 . LEU A 1 285 ? -21.023 -32.62  6.221   1   27.26  ? 281 LEU A CD1 1 
ATOM   2296 C  CD2 . LEU A 1 285 ? -19.354 -34.113 7.302   1   25.22  ? 281 LEU A CD2 1 
ATOM   2297 N  N   . ALA A 1 286 ? -20.526 -37.431 3.199   1   26.46  ? 282 ALA A N   1 
ATOM   2298 C  CA  . ALA A 1 286 ? -21.242 -38.608 2.736   1   24.81  ? 282 ALA A CA  1 
ATOM   2299 C  C   . ALA A 1 286 ? -20.337 -39.783 2.365   1   24.53  ? 282 ALA A C   1 
ATOM   2300 O  O   . ALA A 1 286 ? -20.83  -40.838 1.992   1   21.67  ? 282 ALA A O   1 
ATOM   2301 C  CB  . ALA A 1 286 ? -22.088 -38.242 1.533   1   25.72  ? 282 ALA A CB  1 
ATOM   2302 N  N   . HIS A 1 287 ? -19.016 -39.629 2.495   1   27.67  ? 283 HIS A N   1 
ATOM   2303 C  CA  . HIS A 1 287 ? -18.122 -40.699 2.081   1   27.67  ? 283 HIS A CA  1 
ATOM   2304 C  C   . HIS A 1 287 ? -18.334 -41.972 2.913   1   27.54  ? 283 HIS A C   1 
ATOM   2305 O  O   . HIS A 1 287 ? -18.579 -41.909 4.113   1   26.78  ? 283 HIS A O   1 
ATOM   2306 C  CB  . HIS A 1 287 ? -16.683 -40.217 2.119   1   27.21  ? 283 HIS A CB  1 
ATOM   2307 C  CG  . HIS A 1 287 ? -15.72  -41.147 1.451   1   29.5   ? 283 HIS A CG  1 
ATOM   2308 N  ND1 . HIS A 1 287 ? -15.388 -42.371 2.015   1   25.74  ? 283 HIS A ND1 1 
ATOM   2309 C  CD2 . HIS A 1 287 ? -15.036 -40.992 0.287   1   32.06  ? 283 HIS A CD2 1 
ATOM   2310 C  CE1 . HIS A 1 287 ? -14.531 -42.93  1.174   1   30.2   ? 283 HIS A CE1 1 
ATOM   2311 N  NE2 . HIS A 1 287 ? -14.289 -42.126 0.113   1   30.76  ? 283 HIS A NE2 1 
ATOM   2312 N  N   . PRO A 1 288 ? -18.29  -43.178 2.296   1   26.49  ? 284 PRO A N   1 
ATOM   2313 C  CA  . PRO A 1 288 ? -18.472 -44.426 3.048   1   24.87  ? 284 PRO A CA  1 
ATOM   2314 C  C   . PRO A 1 288 ? -17.555 -44.635 4.251   1   24.74  ? 284 PRO A C   1 
ATOM   2315 O  O   . PRO A 1 288 ? -17.867 -45.428 5.135   1   25.8   ? 284 PRO A O   1 
ATOM   2316 C  CB  . PRO A 1 288 ? -18.231 -45.523 2.01    1   24.67  ? 284 PRO A CB  1 
ATOM   2317 C  CG  . PRO A 1 288 ? -18.347 -44.864 0.664   1   25.55  ? 284 PRO A CG  1 
ATOM   2318 C  CD  . PRO A 1 288 ? -18.127 -43.39  0.843   1   25.81  ? 284 PRO A CD  1 
ATOM   2319 N  N   . PHE A 1 289 ? -16.423 -43.927 4.294   1   26.12  ? 285 PHE A N   1 
ATOM   2320 C  CA  . PHE A 1 289 ? -15.545 -43.99  5.454   1   26.81  ? 285 PHE A CA  1 
ATOM   2321 C  C   . PHE A 1 289 ? -16.287 -43.716 6.767   1   26.59  ? 285 PHE A C   1 
ATOM   2322 O  O   . PHE A 1 289 ? -15.968 -44.299 7.805   1   26.89  ? 285 PHE A O   1 
ATOM   2323 C  CB  . PHE A 1 289 ? -14.382 -43.008 5.272   1   29.18  ? 285 PHE A CB  1 
ATOM   2324 C  CG  . PHE A 1 289 ? -13.34  -43.044 6.365   1   33.44  ? 285 PHE A CG  1 
ATOM   2325 C  CD1 . PHE A 1 289 ? -12.573 -44.181 6.576   1   32.74  ? 285 PHE A CD1 1 
ATOM   2326 C  CD2 . PHE A 1 289 ? -13.135 -41.944 7.192   1   34.09  ? 285 PHE A CD2 1 
ATOM   2327 C  CE1 . PHE A 1 289 ? -11.619 -44.211 7.567   1   32.71  ? 285 PHE A CE1 1 
ATOM   2328 C  CE2 . PHE A 1 289 ? -12.187 -41.995 8.196   1   35.09  ? 285 PHE A CE2 1 
ATOM   2329 C  CZ  . PHE A 1 289 ? -11.437 -43.128 8.377   1   33.21  ? 285 PHE A CZ  1 
ATOM   2330 N  N   . PHE A 1 290 ? -17.297 -42.841 6.711   1   25.69  ? 286 PHE A N   1 
ATOM   2331 C  CA  . PHE A 1 290 ? -18.023 -42.415 7.896   1   28.21  ? 286 PHE A CA  1 
ATOM   2332 C  C   . PHE A 1 290 ? -19.262 -43.232 8.268   1   30.61  ? 286 PHE A C   1 
ATOM   2333 O  O   . PHE A 1 290 ? -19.977 -42.869 9.208   1   33.43  ? 286 PHE A O   1 
ATOM   2334 C  CB  . PHE A 1 290 ? -18.42  -40.945 7.699   1   26.21  ? 286 PHE A CB  1 
ATOM   2335 C  CG  . PHE A 1 290 ? -17.227 -40.041 7.557   1   25.37  ? 286 PHE A CG  1 
ATOM   2336 C  CD1 . PHE A 1 290 ? -16.313 -39.914 8.585   1   24.99  ? 286 PHE A CD1 1 
ATOM   2337 C  CD2 . PHE A 1 290 ? -17.032 -39.295 6.404   1   25.29  ? 286 PHE A CD2 1 
ATOM   2338 C  CE1 . PHE A 1 290 ? -15.227 -39.055 8.467   1   24.72  ? 286 PHE A CE1 1 
ATOM   2339 C  CE2 . PHE A 1 290 ? -15.941 -38.459 6.277   1   24.32  ? 286 PHE A CE2 1 
ATOM   2340 C  CZ  . PHE A 1 290 ? -15.04  -38.344 7.311   1   26.1   ? 286 PHE A CZ  1 
ATOM   2341 N  N   . GLN A 1 291 ? -19.504 -44.353 7.574   1   33.28  ? 287 GLN A N   1 
ATOM   2342 C  CA  . GLN A 1 291 ? -20.747 -45.081 7.759   1   34.72  ? 287 GLN A CA  1 
ATOM   2343 C  C   . GLN A 1 291 ? -21.009 -45.519 9.199   1   36.64  ? 287 GLN A C   1 
ATOM   2344 O  O   . GLN A 1 291 ? -22.164 -45.561 9.625   1   39.58  ? 287 GLN A O   1 
ATOM   2345 C  CB  . GLN A 1 291 ? -20.857 -46.267 6.802   1   41.36  ? 287 GLN A CB  1 
ATOM   2346 C  CG  . GLN A 1 291 ? -19.848 -47.392 7.006   1   50.45  ? 287 GLN A CG  1 
ATOM   2347 C  CD  . GLN A 1 291 ? -20.019 -48.447 5.916   1   57.2   ? 287 GLN A CD  1 
ATOM   2348 O  OE1 . GLN A 1 291 ? -21.059 -49.14  5.84    1   64.53  ? 287 GLN A OE1 1 
ATOM   2349 N  NE2 . GLN A 1 291 ? -19.011 -48.602 5.036   1   48.64  ? 287 GLN A NE2 1 
ATOM   2350 N  N   A ASP A 1 292 ? -19.932 -45.819 9.937   0.5 36.14  ? 288 ASP A N   1 
ATOM   2351 N  N   B ASP A 1 292 ? -19.951 -45.813 9.963   0.5 36.53  ? 288 ASP A N   1 
ATOM   2352 C  CA  A ASP A 1 292 ? -20.051 -46.347 11.286  0.5 37.9   ? 288 ASP A CA  1 
ATOM   2353 C  CA  B ASP A 1 292 ? -20.132 -46.344 11.307  0.5 38.39  ? 288 ASP A CA  1 
ATOM   2354 C  C   A ASP A 1 292 ? -19.631 -45.371 12.386  0.5 39.77  ? 288 ASP A C   1 
ATOM   2355 C  C   B ASP A 1 292 ? -19.833 -45.368 12.447  0.5 39.31  ? 288 ASP A C   1 
ATOM   2356 O  O   A ASP A 1 292 ? -19.205 -45.811 13.451  0.5 41.77  ? 288 ASP A O   1 
ATOM   2357 O  O   B ASP A 1 292 ? -19.712 -45.803 13.591  0.5 38.56  ? 288 ASP A O   1 
ATOM   2358 C  CB  A ASP A 1 292 ? -19.232 -47.652 11.39   0.5 36.38  ? 288 ASP A CB  1 
ATOM   2359 C  CB  B ASP A 1 292 ? -19.286 -47.621 11.456  0.5 38.03  ? 288 ASP A CB  1 
ATOM   2360 C  CG  A ASP A 1 292 ? -17.788 -47.598 10.903  0.5 34.51  ? 288 ASP A CG  1 
ATOM   2361 C  CG  B ASP A 1 292 ? -19.873 -48.825 10.744  0.5 36.47  ? 288 ASP A CG  1 
ATOM   2362 O  OD1 A ASP A 1 292 ? -17.373 -46.545 10.347  0.5 31.32  ? 288 ASP A OD1 1 
ATOM   2363 O  OD1 B ASP A 1 292 ? -21.091 -48.796 10.419  0.5 37.23  ? 288 ASP A OD1 1 
ATOM   2364 O  OD2 A ASP A 1 292 ? -17.068 -48.604 11.077  0.5 31.28  ? 288 ASP A OD2 1 
ATOM   2365 O  OD2 B ASP A 1 292 ? -19.125 -49.785 10.498  0.5 34.63  ? 288 ASP A OD2 1 
ATOM   2366 N  N   . VAL A 1 293 ? -19.779 -44.058 12.148  1   38.37  ? 289 VAL A N   1 
ATOM   2367 C  CA  . VAL A 1 293 ? -19.448 -43.054 13.16   1   41.09  ? 289 VAL A CA  1 
ATOM   2368 C  C   . VAL A 1 293 ? -20.461 -42.984 14.294  1   45.88  ? 289 VAL A C   1 
ATOM   2369 O  O   . VAL A 1 293 ? -21.67  -43.026 14.052  1   40.2   ? 289 VAL A O   1 
ATOM   2370 C  CB  . VAL A 1 293 ? -19.254 -41.602 12.651  1   43.72  ? 289 VAL A CB  1 
ATOM   2371 C  CG1 . VAL A 1 293 ? -17.888 -41.414 12.066  1   42.69  ? 289 VAL A CG1 1 
ATOM   2372 C  CG2 . VAL A 1 293 ? -20.342 -41.161 11.676  1   47.77  ? 289 VAL A CG2 1 
ATOM   2373 N  N   . GLY B 2 1   ? -15.242 -23.998 -11.954 1   31.65  ? 171 GLY B N   1 
ATOM   2374 C  CA  . GLY B 2 1   ? -14.417 -24.761 -11.037 1   29.9   ? 171 GLY B CA  1 
ATOM   2375 C  C   . GLY B 2 1   ? -14.534 -24.248 -9.603  1   30.34  ? 171 GLY B C   1 
ATOM   2376 O  O   . GLY B 2 1   ? -15.423 -23.457 -9.286  1   30.33  ? 171 GLY B O   1 
ATOM   2377 N  N   . VAL B 2 2   ? -13.605 -24.686 -8.747  1   28.39  ? 172 VAL B N   1 
ATOM   2378 C  CA  . VAL B 2 2   ? -13.664 -24.377 -7.331  1   29.47  ? 172 VAL B CA  1 
ATOM   2379 C  C   . VAL B 2 2   ? -13.582 -22.876 -7.03   1   30.41  ? 172 VAL B C   1 
ATOM   2380 O  O   . VAL B 2 2   ? -14.07  -22.424 -5.996  1   30.45  ? 172 VAL B O   1 
ATOM   2381 C  CB  . VAL B 2 2   ? -12.585 -25.201 -6.579  1   30.08  ? 172 VAL B CB  1 
ATOM   2382 C  CG1 . VAL B 2 2   ? -11.171 -24.664 -6.842  1   28.92  ? 172 VAL B CG1 1 
ATOM   2383 C  CG2 . VAL B 2 2   ? -12.9   -25.268 -5.086  1   27.04  ? 172 VAL B CG2 1 
ATOM   2384 N  N   . ASN B 2 3   ? -13.001 -22.086 -7.943  1   31.89  ? 173 ASN B N   1 
ATOM   2385 C  CA  . ASN B 2 3   ? -12.988 -20.634 -7.786  1   30.7   ? 173 ASN B CA  1 
ATOM   2386 C  C   . ASN B 2 3   ? -14.381 -20.006 -7.808  1   31.11  ? 173 ASN B C   1 
ATOM   2387 O  O   . ASN B 2 3   ? -14.551 -18.872 -7.373  1   32.07  ? 173 ASN B O   1 
ATOM   2388 C  CB  . ASN B 2 3   ? -12.132 -19.994 -8.869  1   31.74  ? 173 ASN B CB  1 
ATOM   2389 C  CG  . ASN B 2 3   ? -10.686 -20.376 -8.759  1   30.94  ? 173 ASN B CG  1 
ATOM   2390 O  OD1 . ASN B 2 3   ? -10.219 -20.867 -7.721  1   32.15  ? 173 ASN B OD1 1 
ATOM   2391 N  ND2 . ASN B 2 3   ? -9.949  -20.17  -9.826  1   30.15  ? 173 ASN B ND2 1 
ATOM   2392 N  N   . GLU B 2 4   ? -15.362 -20.749 -8.334  1   31.42  ? 174 GLU B N   1 
ATOM   2393 C  CA  . GLU B 2 4   ? -16.762 -20.366 -8.291  1   32.27  ? 174 GLU B CA  1 
ATOM   2394 C  C   . GLU B 2 4   ? -17.554 -21.139 -7.233  1   30.7   ? 174 GLU B C   1 
ATOM   2395 O  O   . GLU B 2 4   ? -18.775 -21.076 -7.225  1   26.87  ? 174 GLU B O   1 
ATOM   2396 C  CB  . GLU B 2 4   ? -17.386 -20.625 -9.67   1   35.86  ? 174 GLU B CB  1 
ATOM   2397 C  CG  . GLU B 2 4   ? -16.606 -20.035 -10.831 1   41.24  ? 174 GLU B CG  1 
ATOM   2398 C  CD  . GLU B 2 4   ? -17.252 -20.238 -12.192 1   46.05  ? 174 GLU B CD  1 
ATOM   2399 O  OE1 . GLU B 2 4   ? -18.274 -20.956 -12.277 1   51.95  ? 174 GLU B OE1 1 
ATOM   2400 O  OE2 . GLU B 2 4   ? -16.761 -19.638 -13.172 1   42.03  ? 174 GLU B OE2 1 
ATOM   2401 N  N   . VAL B 2 5   ? -16.851 -21.871 -6.356  1   29.77  ? 175 VAL B N   1 
ATOM   2402 C  CA  . VAL B 2 5   ? -17.445 -22.702 -5.317  1   31.39  ? 175 VAL B CA  1 
ATOM   2403 C  C   . VAL B 2 5   ? -18.803 -23.291 -5.7    1   30.83  ? 175 VAL B C   1 
ATOM   2404 O  O   . VAL B 2 5   ? -19.823 -22.935 -5.119  1   29.32  ? 175 VAL B O   1 
ATOM   2405 C  CB  . VAL B 2 5   ? -17.52  -21.92  -3.963  1   31.17  ? 175 VAL B CB  1 
ATOM   2406 C  CG1 . VAL B 2 5   ? -16.124 -21.67  -3.428  1   32.65  ? 175 VAL B CG1 1 
ATOM   2407 C  CG2 . VAL B 2 5   ? -18.299 -20.607 -4.077  1   29.05  ? 175 VAL B CG2 1 
ATOM   2408 N  N   . PRO B 2 6   ? -18.843 -24.257 -6.644  1   31.26  ? 176 PRO B N   1 
ATOM   2409 C  CA  . PRO B 2 6   ? -20.102 -24.868 -7.072  1   31.3   ? 176 PRO B CA  1 
ATOM   2410 C  C   . PRO B 2 6   ? -20.915 -25.445 -5.915  1   31.48  ? 176 PRO B C   1 
ATOM   2411 O  O   . PRO B 2 6   ? -22.138 -25.337 -5.91   1   33.58  ? 176 PRO B O   1 
ATOM   2412 C  CB  . PRO B 2 6   ? -19.668 -26     -8.028  1   29.8   ? 176 PRO B CB  1 
ATOM   2413 C  CG  . PRO B 2 6   ? -18.216 -25.816 -8.292  1   28.3   ? 176 PRO B CG  1 
ATOM   2414 C  CD  . PRO B 2 6   ? -17.661 -24.863 -7.278  1   32.53  ? 176 PRO B CD  1 
ATOM   2415 N  N   . ASP B 2 7   ? -20.22  -26.062 -4.947  1   29.62  ? 177 ASP B N   1 
ATOM   2416 C  CA  . ASP B 2 7   ? -20.882 -26.746 -3.849  1   30.82  ? 177 ASP B CA  1 
ATOM   2417 C  C   . ASP B 2 7   ? -21.432 -25.815 -2.776  1   27.53  ? 177 ASP B C   1 
ATOM   2418 O  O   . ASP B 2 7   ? -22.15  -26.28  -1.898  1   29.22  ? 177 ASP B O   1 
ATOM   2419 C  CB  . ASP B 2 7   ? -19.957 -27.81  -3.209  1   30.38  ? 177 ASP B CB  1 
ATOM   2420 C  CG  . ASP B 2 7   ? -19.928 -29.078 -4.016  1   29.97  ? 177 ASP B CG  1 
ATOM   2421 O  OD1 . ASP B 2 7   ? -20.394 -29.045 -5.162  1   30.38  ? 177 ASP B OD1 1 
ATOM   2422 O  OD2 . ASP B 2 7   ? -19.485 -30.126 -3.473  1   31.22  ? 177 ASP B OD2 1 
ATOM   2423 N  N   . TYR B 2 8   ? -21.086 -24.523 -2.847  1   26.93  ? 178 TYR B N   1 
ATOM   2424 C  CA  . TYR B 2 8   ? -21.44  -23.567 -1.807  1   26.28  ? 178 TYR B CA  1 
ATOM   2425 C  C   . TYR B 2 8   ? -22.092 -22.273 -2.289  1   25.69  ? 178 TYR B C   1 
ATOM   2426 O  O   . TYR B 2 8   ? -22.609 -21.521 -1.464  1   26.03  ? 178 TYR B O   1 
ATOM   2427 C  CB  . TYR B 2 8   ? -20.176 -23.197 -0.983  1   26.02  ? 178 TYR B CB  1 
ATOM   2428 C  CG  . TYR B 2 8   ? -19.55  -24.395 -0.312  1   23.43  ? 178 TYR B CG  1 
ATOM   2429 C  CD1 . TYR B 2 8   ? -20.105 -24.941 0.835   1   22.9   ? 178 TYR B CD1 1 
ATOM   2430 C  CD2 . TYR B 2 8   ? -18.44  -25.025 -0.858  1   20.71  ? 178 TYR B CD2 1 
ATOM   2431 C  CE1 . TYR B 2 8   ? -19.535 -26.046 1.464   1   20.2   ? 178 TYR B CE1 1 
ATOM   2432 C  CE2 . TYR B 2 8   ? -17.873 -26.142 -0.251  1   21.03  ? 178 TYR B CE2 1 
ATOM   2433 C  CZ  . TYR B 2 8   ? -18.42  -26.647 0.919   1   19.97  ? 178 TYR B CZ  1 
ATOM   2434 O  OH  . TYR B 2 8   ? -17.874 -27.766 1.516   1   19.12  ? 178 TYR B OH  1 
ATOM   2435 N  N   . HIS B 2 9   ? -22.098 -22.006 -3.603  1   28.5   ? 179 HIS B N   1 
ATOM   2436 C  CA  . HIS B 2 9   ? -22.529 -20.691 -4.074  1   33.76  ? 179 HIS B CA  1 
ATOM   2437 C  C   . HIS B 2 9   ? -23.997 -20.381 -3.754  1   30.62  ? 179 HIS B C   1 
ATOM   2438 O  O   . HIS B 2 9   ? -24.336 -19.227 -3.507  1   29.39  ? 179 HIS B O   1 
ATOM   2439 C  CB  . HIS B 2 9   ? -22.218 -20.475 -5.587  1   37.62  ? 179 HIS B CB  1 
ATOM   2440 C  CG  . HIS B 2 9   ? -23.177 -21.108 -6.548  1   47.74  ? 179 HIS B CG  1 
ATOM   2441 N  ND1 . HIS B 2 9   ? -24.063 -20.344 -7.286  1   52.3   ? 179 HIS B ND1 1 
ATOM   2442 C  CD2 . HIS B 2 9   ? -23.378 -22.413 -6.843  1   54     ? 179 HIS B CD2 1 
ATOM   2443 C  CE1 . HIS B 2 9   ? -24.772 -21.206 -8.007  1   59.29  ? 179 HIS B CE1 1 
ATOM   2444 N  NE2 . HIS B 2 9   ? -24.383 -22.466 -7.774  1   57.12  ? 179 HIS B NE2 1 
ATOM   2445 N  N   . GLU B 2 10  ? -24.861 -21.408 -3.747  1   32.88  ? 180 GLU B N   1 
ATOM   2446 C  CA  . GLU B 2 10  ? -26.262 -21.253 -3.371  1   33.44  ? 180 GLU B CA  1 
ATOM   2447 C  C   . GLU B 2 10  ? -26.433 -20.953 -1.881  1   30.77  ? 180 GLU B C   1 
ATOM   2448 O  O   . GLU B 2 10  ? -27.145 -20.015 -1.522  1   29.05  ? 180 GLU B O   1 
ATOM   2449 C  CB  . GLU B 2 10  ? -27.077 -22.504 -3.706  1   39.95  ? 180 GLU B CB  1 
ATOM   2450 C  CG  . GLU B 2 10  ? -28.046 -22.361 -4.862  1   51.1   ? 180 GLU B CG  1 
ATOM   2451 C  CD  . GLU B 2 10  ? -29.033 -23.518 -4.963  1   60.61  ? 180 GLU B CD  1 
ATOM   2452 O  OE1 . GLU B 2 10  ? -29.845 -23.718 -4.026  1   52.56  ? 180 GLU B OE1 1 
ATOM   2453 O  OE2 . GLU B 2 10  ? -28.972 -24.241 -5.983  1   71.61  ? 180 GLU B OE2 1 
ATOM   2454 N  N   . ASP B 2 11  ? -25.784 -21.751 -1.02   1   27.88  ? 181 ASP B N   1 
ATOM   2455 C  CA  . ASP B 2 11  ? -25.763 -21.477 0.412   1   29.19  ? 181 ASP B CA  1 
ATOM   2456 C  C   . ASP B 2 11  ? -25.267 -20.056 0.666   1   28.47  ? 181 ASP B C   1 
ATOM   2457 O  O   . ASP B 2 11  ? -25.845 -19.328 1.467   1   29.24  ? 181 ASP B O   1 
ATOM   2458 C  CB  . ASP B 2 11  ? -24.873 -22.465 1.189   1   28.98  ? 181 ASP B CB  1 
ATOM   2459 C  CG  . ASP B 2 11  ? -25.364 -23.894 1.325   1   31.61  ? 181 ASP B CG  1 
ATOM   2460 O  OD1 . ASP B 2 11  ? -26.519 -24.162 0.969   1   30.67  ? 181 ASP B OD1 1 
ATOM   2461 O  OD2 . ASP B 2 11  ? -24.585 -24.747 1.803   1   36.99  ? 181 ASP B OD2 1 
ATOM   2462 N  N   . ILE B 2 12  ? -24.193 -19.664 -0.031  1   29.42  ? 182 ILE B N   1 
ATOM   2463 C  CA  . ILE B 2 12  ? -23.609 -18.349 0.166   1   29.23  ? 182 ILE B CA  1 
ATOM   2464 C  C   . ILE B 2 12  ? -24.584 -17.25  -0.255  1   29.84  ? 182 ILE B C   1 
ATOM   2465 O  O   . ILE B 2 12  ? -24.762 -16.284 0.477   1   31.18  ? 182 ILE B O   1 
ATOM   2466 C  CB  . ILE B 2 12  ? -22.254 -18.212 -0.527  1   27.27  ? 182 ILE B CB  1 
ATOM   2467 C  CG1 . ILE B 2 12  ? -21.176 -19.077 0.171   1   27.88  ? 182 ILE B CG1 1 
ATOM   2468 C  CG2 . ILE B 2 12  ? -21.804 -16.76  -0.561  1   28.43  ? 182 ILE B CG2 1 
ATOM   2469 C  CD1 . ILE B 2 12  ? -19.925 -19.428 -0.763  1   27.6   ? 182 ILE B CD1 1 
ATOM   2470 N  N   . HIS B 2 13  ? -25.199 -17.397 -1.432  1   29.89  ? 183 HIS B N   1 
ATOM   2471 C  CA  . HIS B 2 13  ? -26.214 -16.456 -1.892  1   31.62  ? 183 HIS B CA  1 
ATOM   2472 C  C   . HIS B 2 13  ? -27.367 -16.286 -0.896  1   29.88  ? 183 HIS B C   1 
ATOM   2473 O  O   . HIS B 2 13  ? -27.749 -15.168 -0.556  1   31.26  ? 183 HIS B O   1 
ATOM   2474 C  CB  . HIS B 2 13  ? -26.792 -16.88  -3.262  1   29.67  ? 183 HIS B CB  1 
ATOM   2475 C  CG  . HIS B 2 13  ? -27.797 -15.892 -3.772  1   28.29  ? 183 HIS B CG  1 
ATOM   2476 N  ND1 . HIS B 2 13  ? -29.127 -16.172 -3.801  1   26.99  ? 183 HIS B ND1 1 
ATOM   2477 C  CD2 . HIS B 2 13  ? -27.609 -14.622 -4.199  1   29.86  ? 183 HIS B CD2 1 
ATOM   2478 C  CE1 . HIS B 2 13  ? -29.717 -15.081 -4.264  1   28.84  ? 183 HIS B CE1 1 
ATOM   2479 N  NE2 . HIS B 2 13  ? -28.826 -14.119 -4.509  1   27.23  ? 183 HIS B NE2 1 
ATOM   2480 N  N   . THR B 2 14  ? -27.912 -17.41  -0.419  1   28.51  ? 184 THR B N   1 
ATOM   2481 C  CA  . THR B 2 14  ? -28.96  -17.387 0.592   1   29.64  ? 184 THR B CA  1 
ATOM   2482 C  C   . THR B 2 14  ? -28.554 -16.659 1.874   1   29.73  ? 184 THR B C   1 
ATOM   2483 O  O   . THR B 2 14  ? -29.333 -15.885 2.425   1   30.08  ? 184 THR B O   1 
ATOM   2484 C  CB  . THR B 2 14  ? -29.387 -18.809 0.922   1   28.31  ? 184 THR B CB  1 
ATOM   2485 O  OG1 . THR B 2 14  ? -30.048 -19.349 -0.223  1   29.93  ? 184 THR B OG1 1 
ATOM   2486 C  CG2 . THR B 2 14  ? -30.322 -18.875 2.136   1   26.95  ? 184 THR B CG2 1 
ATOM   2487 N  N   . TYR B 2 15  ? -27.331 -16.925 2.346   1   29.54  ? 185 TYR B N   1 
ATOM   2488 C  CA  . TYR B 2 15  ? -26.811 -16.297 3.548   1   28.36  ? 185 TYR B CA  1 
ATOM   2489 C  C   . TYR B 2 15  ? -26.634 -14.793 3.363   1   25.84  ? 185 TYR B C   1 
ATOM   2490 O  O   . TYR B 2 15  ? -26.963 -14.013 4.252   1   27.8   ? 185 TYR B O   1 
ATOM   2491 C  CB  . TYR B 2 15  ? -25.479 -16.941 3.952   1   31.83  ? 185 TYR B CB  1 
ATOM   2492 C  CG  . TYR B 2 15  ? -24.886 -16.355 5.209   1   31.78  ? 185 TYR B CG  1 
ATOM   2493 C  CD1 . TYR B 2 15  ? -25.582 -16.388 6.409   1   38.66  ? 185 TYR B CD1 1 
ATOM   2494 C  CD2 . TYR B 2 15  ? -23.645 -15.745 5.195   1   33.88  ? 185 TYR B CD2 1 
ATOM   2495 C  CE1 . TYR B 2 15  ? -25.05  -15.835 7.571   1   38.87  ? 185 TYR B CE1 1 
ATOM   2496 C  CE2 . TYR B 2 15  ? -23.099 -15.193 6.349   1   38.75  ? 185 TYR B CE2 1 
ATOM   2497 C  CZ  . TYR B 2 15  ? -23.809 -15.238 7.536   1   41.19  ? 185 TYR B CZ  1 
ATOM   2498 O  OH  . TYR B 2 15  ? -23.293 -14.707 8.682   1   52.65  ? 185 TYR B OH  1 
ATOM   2499 N  N   . LEU B 2 16  ? -26.114 -14.382 2.203   1   26.4   ? 186 LEU B N   1 
ATOM   2500 C  CA  . LEU B 2 16  ? -25.922 -12.967 1.925   1   27.65  ? 186 LEU B CA  1 
ATOM   2501 C  C   . LEU B 2 16  ? -27.256 -12.226 1.892   1   30.67  ? 186 LEU B C   1 
ATOM   2502 O  O   . LEU B 2 16  ? -27.349 -11.096 2.371   1   34.99  ? 186 LEU B O   1 
ATOM   2503 C  CB  . LEU B 2 16  ? -25.183 -12.774 0.615   1   27.65  ? 186 LEU B CB  1 
ATOM   2504 C  CG  . LEU B 2 16  ? -23.738 -13.288 0.589   1   27.53  ? 186 LEU B CG  1 
ATOM   2505 C  CD1 . LEU B 2 16  ? -23.12  -13.097 -0.814  1   27.36  ? 186 LEU B CD1 1 
ATOM   2506 C  CD2 . LEU B 2 16  ? -22.921 -12.63  1.661   1   28.31  ? 186 LEU B CD2 1 
ATOM   2507 N  N   . ARG B 2 17  ? -28.291 -12.871 1.338   1   29.01  ? 187 ARG B N   1 
ATOM   2508 C  CA  . ARG B 2 17  ? -29.624 -12.289 1.306   1   30.73  ? 187 ARG B CA  1 
ATOM   2509 C  C   . ARG B 2 17  ? -30.169 -12.025 2.71    1   34.47  ? 187 ARG B C   1 
ATOM   2510 O  O   . ARG B 2 17  ? -30.866 -11.035 2.948   1   32.19  ? 187 ARG B O   1 
ATOM   2511 C  CB  . ARG B 2 17  ? -30.588 -13.199 0.528   1   28.71  ? 187 ARG B CB  1 
ATOM   2512 C  CG  . ARG B 2 17  ? -30.356 -13.173 -0.996  1   30.31  ? 187 ARG B CG  1 
ATOM   2513 C  CD  . ARG B 2 17  ? -30.809 -11.877 -1.658  1   28.92  ? 187 ARG B CD  1 
ATOM   2514 N  NE  . ARG B 2 17  ? -32.256 -11.698 -1.571  1   28.58  ? 187 ARG B NE  1 
ATOM   2515 C  CZ  . ARG B 2 17  ? -33.143 -12.247 -2.399  1   30.62  ? 187 ARG B CZ  1 
ATOM   2516 N  NH1 . ARG B 2 17  ? -32.794 -12.717 -3.587  1   33.82  ? 187 ARG B NH1 1 
ATOM   2517 N  NH2 . ARG B 2 17  ? -34.423 -12.273 -2.048  1   27.2   ? 187 ARG B NH2 1 
ATOM   2518 N  N   . GLU B 2 18  ? -29.844 -12.929 3.636   1   35.23  ? 188 GLU B N   1 
ATOM   2519 C  CA  . GLU B 2 18  ? -30.23  -12.78  5.026   1   39.31  ? 188 GLU B CA  1 
ATOM   2520 C  C   . GLU B 2 18  ? -29.44  -11.634 5.669   1   39.57  ? 188 GLU B C   1 
ATOM   2521 O  O   . GLU B 2 18  ? -30.005 -10.781 6.356   1   36.96  ? 188 GLU B O   1 
ATOM   2522 C  CB  . GLU B 2 18  ? -30.006 -14.129 5.718   1   42.15  ? 188 GLU B CB  1 
ATOM   2523 C  CG  . GLU B 2 18  ? -30.52  -14.214 7.132   1   46.73  ? 188 GLU B CG  1 
ATOM   2524 C  CD  . GLU B 2 18  ? -30.116 -15.491 7.834   1   53.82  ? 188 GLU B CD  1 
ATOM   2525 O  OE1 . GLU B 2 18  ? -29.883 -16.516 7.146   1   54.33  ? 188 GLU B OE1 1 
ATOM   2526 O  OE2 . GLU B 2 18  ? -29.996 -15.448 9.079   1   48.21  ? 188 GLU B OE2 1 
ATOM   2527 N  N   . MET B 2 19  ? -28.132 -11.593 5.398   1   36.41  ? 189 MET B N   1 
ATOM   2528 C  CA  . MET B 2 19  ? -27.25  -10.636 6.042   1   39.44  ? 189 MET B CA  1 
ATOM   2529 C  C   . MET B 2 19  ? -27.456 -9.204  5.55    1   36.55  ? 189 MET B C   1 
ATOM   2530 O  O   . MET B 2 19  ? -27.287 -8.271  6.326   1   34.11  ? 189 MET B O   1 
ATOM   2531 C  CB  . MET B 2 19  ? -25.798 -11.054 5.839   1   36.1   ? 189 MET B CB  1 
ATOM   2532 C  CG  . MET B 2 19  ? -25.441 -12.32  6.605   1   42.11  ? 189 MET B CG  1 
ATOM   2533 S  SD  . MET B 2 19  ? -25.606 -12.168 8.41    1   45.65  ? 189 MET B SD  1 
ATOM   2534 C  CE  . MET B 2 19  ? -27.097 -13.049 8.73    1   42.84  ? 189 MET B CE  1 
ATOM   2535 N  N   . GLU B 2 20  ? -27.821 -9.033  4.275   1   32.55  ? 190 GLU B N   1 
ATOM   2536 C  CA  . GLU B 2 20  ? -28.021 -7.698  3.74    1   33.94  ? 190 GLU B CA  1 
ATOM   2537 C  C   . GLU B 2 20  ? -29.228 -7.031  4.392   1   32.44  ? 190 GLU B C   1 
ATOM   2538 O  O   . GLU B 2 20  ? -29.249 -5.81   4.512   1   32.67  ? 190 GLU B O   1 
ATOM   2539 C  CB  . GLU B 2 20  ? -28.157 -7.68   2.197   1   33.98  ? 190 GLU B CB  1 
ATOM   2540 C  CG  . GLU B 2 20  ? -29.44  -8.244  1.63    1   33.27  ? 190 GLU B CG  1 
ATOM   2541 C  CD  . GLU B 2 20  ? -29.58  -8.075  0.126   1   34.83  ? 190 GLU B CD  1 
ATOM   2542 O  OE1 . GLU B 2 20  ? -28.727 -7.399  -0.509  1   32.01  ? 190 GLU B OE1 1 
ATOM   2543 O  OE2 . GLU B 2 20  ? -30.567 -8.63   -0.416  1   30.4   ? 190 GLU B OE2 1 
ATOM   2544 N  N   . VAL B 2 21  ? -30.221 -7.833  4.807   1   32.07  ? 191 VAL B N   1 
ATOM   2545 C  CA  . VAL B 2 21  ? -31.311 -7.334  5.632   1   32.29  ? 191 VAL B CA  1 
ATOM   2546 C  C   . VAL B 2 21  ? -30.821 -6.879  7.01    1   32.83  ? 191 VAL B C   1 
ATOM   2547 O  O   . VAL B 2 21  ? -31.161 -5.792  7.457   1   37     ? 191 VAL B O   1 
ATOM   2548 C  CB  . VAL B 2 21  ? -32.45  -8.38   5.759   1   31.3   ? 191 VAL B CB  1 
ATOM   2549 C  CG1 . VAL B 2 21  ? -33.532 -7.905  6.736   1   26.8   ? 191 VAL B CG1 1 
ATOM   2550 C  CG2 . VAL B 2 21  ? -33.069 -8.714  4.389   1   29.6   ? 191 VAL B CG2 1 
ATOM   2551 N  N   . LYS B 2 22  ? -30.005 -7.696  7.68    1   39.16  ? 192 LYS B N   1 
ATOM   2552 C  CA  . LYS B 2 22  ? -29.407 -7.32   8.953   1   41.94  ? 192 LYS B CA  1 
ATOM   2553 C  C   . LYS B 2 22  ? -28.531 -6.066  8.851   1   44.13  ? 192 LYS B C   1 
ATOM   2554 O  O   . LYS B 2 22  ? -28.567 -5.22   9.734   1   44.18  ? 192 LYS B O   1 
ATOM   2555 C  CB  . LYS B 2 22  ? -28.577 -8.497  9.507   1   49.25  ? 192 LYS B CB  1 
ATOM   2556 C  CG  . LYS B 2 22  ? -27.786 -8.169  10.815  1   58.41  ? 192 LYS B CG  1 
ATOM   2557 C  CD  . LYS B 2 22  ? -26.921 -9.305  11.339  1   64.2   ? 192 LYS B CD  1 
ATOM   2558 C  CE  . LYS B 2 22  ? -27.764 -10.404 11.954  1   70.96  ? 192 LYS B CE  1 
ATOM   2559 N  NZ  . LYS B 2 22  ? -26.939 -11.496 12.542  1   71.9   ? 192 LYS B NZ  1 
ATOM   2560 N  N   . CYS B 2 23  ? -27.734 -5.954  7.779   1   45.65  ? 193 CYS B N   1 
ATOM   2561 C  CA  . CYS B 2 23  ? -26.765 -4.875  7.629   1   43.96  ? 193 CYS B CA  1 
ATOM   2562 C  C   . CYS B 2 23  ? -27.339 -3.617  6.984   1   39.95  ? 193 CYS B C   1 
ATOM   2563 O  O   . CYS B 2 23  ? -26.578 -2.756  6.549   1   39.95  ? 193 CYS B O   1 
ATOM   2564 C  CB  . CYS B 2 23  ? -25.539 -5.373  6.855   1   39.92  ? 193 CYS B CB  1 
ATOM   2565 S  SG  . CYS B 2 23  ? -24.561 -6.622  7.761   1   47.73  ? 193 CYS B SG  1 
ATOM   2566 N  N   . LYS B 2 24  ? -28.67  -3.511  6.916   1   37.23  ? 194 LYS B N   1 
ATOM   2567 C  CA  . LYS B 2 24  ? -29.29  -2.451  6.14    1   38.23  ? 194 LYS B CA  1 
ATOM   2568 C  C   . LYS B 2 24  ? -29.351 -1.163  6.959   1   37.34  ? 194 LYS B C   1 
ATOM   2569 O  O   . LYS B 2 24  ? -29.826 -1.173  8.09    1   34.55  ? 194 LYS B O   1 
ATOM   2570 C  CB  . LYS B 2 24  ? -30.696 -2.835  5.691   1   42.92  ? 194 LYS B CB  1 
ATOM   2571 C  CG  . LYS B 2 24  ? -31.215 -1.911  4.597   1   47.48  ? 194 LYS B CG  1 
ATOM   2572 C  CD  . LYS B 2 24  ? -32.68  -2.094  4.246   1   49.62  ? 194 LYS B CD  1 
ATOM   2573 C  CE  . LYS B 2 24  ? -33.06  -1.16   3.117   1   54.47  ? 194 LYS B CE  1 
ATOM   2574 N  NZ  . LYS B 2 24  ? -34.494 -1.273  2.749   1   58.21  ? 194 LYS B NZ  1 
ATOM   2575 N  N   . PRO B 2 25  ? -28.907 -0.011  6.407   1   38.59  ? 195 PRO B N   1 
ATOM   2576 C  CA  . PRO B 2 25  ? -29.086 1.275   7.085   1   38.83  ? 195 PRO B CA  1 
ATOM   2577 C  C   . PRO B 2 25  ? -30.567 1.617   7.234   1   36.56  ? 195 PRO B C   1 
ATOM   2578 O  O   . PRO B 2 25  ? -31.379 1.09    6.486   1   36.16  ? 195 PRO B O   1 
ATOM   2579 C  CB  . PRO B 2 25  ? -28.352 2.278   6.171   1   37.99  ? 195 PRO B CB  1 
ATOM   2580 C  CG  . PRO B 2 25  ? -27.542 1.446   5.193   1   40.37  ? 195 PRO B CG  1 
ATOM   2581 C  CD  . PRO B 2 25  ? -28.227 0.109   5.103   1   39.85  ? 195 PRO B CD  1 
ATOM   2582 N  N   . LYS B 2 26  ? -30.903 2.487   8.197   1   36.24  ? 196 LYS B N   1 
ATOM   2583 C  CA  . LYS B 2 26  ? -32.226 3.089   8.265   1   41.04  ? 196 LYS B CA  1 
ATOM   2584 C  C   . LYS B 2 26  ? -32.474 3.95    7.031   1   41.63  ? 196 LYS B C   1 
ATOM   2585 O  O   . LYS B 2 26  ? -31.693 4.856   6.746   1   41.53  ? 196 LYS B O   1 
ATOM   2586 C  CB  . LYS B 2 26  ? -32.396 4       9.484   1   46.83  ? 196 LYS B CB  1 
ATOM   2587 C  CG  . LYS B 2 26  ? -32.628 3.292   10.816  1   57.07  ? 196 LYS B CG  1 
ATOM   2588 C  CD  . LYS B 2 26  ? -32.657 4.284   12.004  1   62.68  ? 196 LYS B CD  1 
ATOM   2589 C  CE  . LYS B 2 26  ? -33.395 5.587   11.699  1   69.15  ? 196 LYS B CE  1 
ATOM   2590 N  NZ  . LYS B 2 26  ? -32.932 6.709   12.552  1   74.59  ? 196 LYS B NZ  1 
ATOM   2591 N  N   . VAL B 2 27  ? -33.585 3.683   6.334   1   41.95  ? 197 VAL B N   1 
ATOM   2592 C  CA  . VAL B 2 27  ? -33.899 4.355   5.084   1   42.4   ? 197 VAL B CA  1 
ATOM   2593 C  C   . VAL B 2 27  ? -34.044 5.866   5.241   1   41.45  ? 197 VAL B C   1 
ATOM   2594 O  O   . VAL B 2 27  ? -33.623 6.621   4.369   1   46.96  ? 197 VAL B O   1 
ATOM   2595 C  CB  . VAL B 2 27  ? -35.162 3.747   4.442   1   48.03  ? 197 VAL B CB  1 
ATOM   2596 C  CG1 . VAL B 2 27  ? -35.593 4.543   3.201   1   45.19  ? 197 VAL B CG1 1 
ATOM   2597 C  CG2 . VAL B 2 27  ? -34.929 2.267   4.097   1   54.85  ? 197 VAL B CG2 1 
ATOM   2598 N  N   . GLY B 2 28  ? -34.628 6.313   6.353   1   41.11  ? 198 GLY B N   1 
ATOM   2599 C  CA  . GLY B 2 28  ? -34.869 7.735   6.543   1   44.78  ? 198 GLY B CA  1 
ATOM   2600 C  C   . GLY B 2 28  ? -33.902 8.478   7.465   1   47.35  ? 198 GLY B C   1 
ATOM   2601 O  O   . GLY B 2 28  ? -34.272 9.505   8.039   1   51.64  ? 198 GLY B O   1 
ATOM   2602 N  N   . TYR B 2 29  ? -32.745 8.037   7.729   1   40.31  ? 199 TYR B N   1 
ATOM   2603 C  CA  . TYR B 2 29  ? -31.876 8.628   8.785   1   35.62  ? 199 TYR B CA  1 
ATOM   2604 C  C   . TYR B 2 29  ? -31.407 10.029  8.508   1   33.76  ? 199 TYR B C   1 
ATOM   2605 O  O   . TYR B 2 29  ? -31.08  10.724  9.478   1   28.82  ? 199 TYR B O   1 
ATOM   2606 C  CB  . TYR B 2 29  ? -30.658 7.708   8.973   1   33.8   ? 199 TYR B CB  1 
ATOM   2607 C  CG  . TYR B 2 29  ? -29.465 7.812   8.029   1   31.98  ? 199 TYR B CG  1 
ATOM   2608 C  CD1 . TYR B 2 29  ? -28.591 8.89    8.074   1   32.68  ? 199 TYR B CD1 1 
ATOM   2609 C  CD2 . TYR B 2 29  ? -29.178 6.794   7.131   1   32.09  ? 199 TYR B CD2 1 
ATOM   2610 C  CE1 . TYR B 2 29  ? -27.51  8.983   7.217   1   34.44  ? 199 TYR B CE1 1 
ATOM   2611 C  CE2 . TYR B 2 29  ? -28.088 6.865   6.281   1   34.62  ? 199 TYR B CE2 1 
ATOM   2612 C  CZ  . TYR B 2 29  ? -27.251 7.963   6.323   1   35.33  ? 199 TYR B CZ  1 
ATOM   2613 O  OH  . TYR B 2 29  ? -26.178 8.044   5.49    1   35.4   ? 199 TYR B OH  1 
ATOM   2614 N  N   . MET B 2 30  ? -31.331 10.407  7.192   1   34.21  ? 200 MET B N   1 
ATOM   2615 C  CA  . MET B 2 30  ? -30.743 11.709  6.915   1   39.24  ? 200 MET B CA  1 
ATOM   2616 C  C   . MET B 2 30  ? -31.618 12.858  7.415   1   39.88  ? 200 MET B C   1 
ATOM   2617 O  O   . MET B 2 30  ? -31.109 13.896  7.833   1   40.5   ? 200 MET B O   1 
ATOM   2618 C  CB  . MET B 2 30  ? -30.454 11.883  5.419   1   39.61  ? 200 MET B CB  1 
ATOM   2619 C  CG  . MET B 2 30  ? -29.552 13.078  5.129   1   39.82  ? 200 MET B CG  1 
ATOM   2620 S  SD  . MET B 2 30  ? -27.941 12.938  5.961   1   39.85  ? 200 MET B SD  1 
ATOM   2621 C  CE  . MET B 2 30  ? -27.105 11.951  4.832   1   41.33  ? 200 MET B CE  1 
ATOM   2622 N  N   . LYS B 2 31  ? -32.937 12.655  7.396   1   42.55  ? 201 LYS B N   1 
ATOM   2623 C  CA  . LYS B 2 31  ? -33.879 13.63   7.921   1   43.08  ? 201 LYS B CA  1 
ATOM   2624 C  C   . LYS B 2 31  ? -33.751 13.796  9.431   1   39.99  ? 201 LYS B C   1 
ATOM   2625 O  O   . LYS B 2 31  ? -34.112 14.834  9.978   1   43.08  ? 201 LYS B O   1 
ATOM   2626 C  CB  . LYS B 2 31  ? -35.32  13.189  7.627   1   49.58  ? 201 LYS B CB  1 
ATOM   2627 C  CG  . LYS B 2 31  ? -35.677 13.037  6.15    1   57.95  ? 201 LYS B CG  1 
ATOM   2628 C  CD  . LYS B 2 31  ? -37.058 12.369  5.984   1   66.97  ? 201 LYS B CD  1 
ATOM   2629 C  CE  . LYS B 2 31  ? -37.763 12.731  4.687   1   71.82  ? 201 LYS B CE  1 
ATOM   2630 N  NZ  . LYS B 2 31  ? -39.242 12.635  4.831   1   71.59  ? 201 LYS B NZ  1 
ATOM   2631 N  N   . LYS B 2 32  ? -33.267 12.746  10.103  1   42.32  ? 202 LYS B N   1 
ATOM   2632 C  CA  . LYS B 2 32  ? -33.05  12.782  11.542  1   45.68  ? 202 LYS B CA  1 
ATOM   2633 C  C   . LYS B 2 32  ? -31.661 13.287  11.927  1   43.24  ? 202 LYS B C   1 
ATOM   2634 O  O   . LYS B 2 32  ? -31.346 13.356  13.111  1   41.48  ? 202 LYS B O   1 
ATOM   2635 C  CB  . LYS B 2 32  ? -33.271 11.375  12.133  1   52.15  ? 202 LYS B CB  1 
ATOM   2636 C  CG  . LYS B 2 32  ? -34.736 10.913  12.041  1   62.11  ? 202 LYS B CG  1 
ATOM   2637 C  CD  . LYS B 2 32  ? -34.925 9.381   12.014  1   68.68  ? 202 LYS B CD  1 
ATOM   2638 C  CE  . LYS B 2 32  ? -36.273 8.971   11.443  1   70.54  ? 202 LYS B CE  1 
ATOM   2639 N  NZ  . LYS B 2 32  ? -37.413 9.519   12.23   1   69.38  ? 202 LYS B NZ  1 
ATOM   2640 N  N   . GLN B 2 33  ? -30.829 13.61   10.925  1   37.53  ? 203 GLN B N   1 
ATOM   2641 C  CA  . GLN B 2 33  ? -29.538 14.242  11.15   1   34.7   ? 203 GLN B CA  1 
ATOM   2642 C  C   . GLN B 2 33  ? -29.698 15.758  11.071  1   33.03  ? 203 GLN B C   1 
ATOM   2643 O  O   . GLN B 2 33  ? -29.955 16.309  10.004  1   34.84  ? 203 GLN B O   1 
ATOM   2644 C  CB  . GLN B 2 33  ? -28.507 13.759  10.115  1   33.04  ? 203 GLN B CB  1 
ATOM   2645 C  CG  . GLN B 2 33  ? -28.1   12.296  10.28   1   31.41  ? 203 GLN B CG  1 
ATOM   2646 C  CD  . GLN B 2 33  ? -26.985 12.089  11.269  1   29.43  ? 203 GLN B CD  1 
ATOM   2647 O  OE1 . GLN B 2 33  ? -26.401 13.025  11.793  1   28.36  ? 203 GLN B OE1 1 
ATOM   2648 N  NE2 . GLN B 2 33  ? -26.654 10.845  11.535  1   30.36  ? 203 GLN B NE2 1 
ATOM   2649 N  N   . PRO B 2 34  ? -29.548 16.492  12.195  1   34.62  ? 204 PRO B N   1 
ATOM   2650 C  CA  . PRO B 2 34  ? -29.781 17.934  12.185  1   34.83  ? 204 PRO B CA  1 
ATOM   2651 C  C   . PRO B 2 34  ? -28.825 18.718  11.286  1   33.92  ? 204 PRO B C   1 
ATOM   2652 O  O   . PRO B 2 34  ? -29.225 19.709  10.692  1   31.78  ? 204 PRO B O   1 
ATOM   2653 C  CB  . PRO B 2 34  ? -29.636 18.318  13.668  1   33.43  ? 204 PRO B CB  1 
ATOM   2654 C  CG  . PRO B 2 34  ? -28.79  17.24   14.258  1   34.02  ? 204 PRO B CG  1 
ATOM   2655 C  CD  . PRO B 2 34  ? -29.149 15.988  13.52   1   33.89  ? 204 PRO B CD  1 
ATOM   2656 N  N   . ASP B 2 35  ? -27.569 18.268  11.175  1   35.95  ? 205 ASP B N   1 
ATOM   2657 C  CA  . ASP B 2 35  ? -26.522 19.095  10.596  1   35.64  ? 205 ASP B CA  1 
ATOM   2658 C  C   . ASP B 2 35  ? -25.952 18.599  9.268   1   38.45  ? 205 ASP B C   1 
ATOM   2659 O  O   . ASP B 2 35  ? -25.125 19.29   8.672   1   39.88  ? 205 ASP B O   1 
ATOM   2660 C  CB  . ASP B 2 35  ? -25.367 19.245  11.599  1   35.74  ? 205 ASP B CB  1 
ATOM   2661 C  CG  . ASP B 2 35  ? -24.55  20.503  11.375  1   36.82  ? 205 ASP B CG  1 
ATOM   2662 O  OD1 . ASP B 2 35  ? -25.146 21.596  11.38   1   40.01  ? 205 ASP B OD1 1 
ATOM   2663 O  OD2 . ASP B 2 35  ? -23.305 20.392  11.191  1   35.49  ? 205 ASP B OD2 1 
ATOM   2664 N  N   . ILE B 2 36  ? -26.38  17.412  8.813   1   38.73  ? 206 ILE B N   1 
ATOM   2665 C  CA  . ILE B 2 36  ? -25.891 16.871  7.559   1   38.57  ? 206 ILE B CA  1 
ATOM   2666 C  C   . ILE B 2 36  ? -27.031 16.434  6.635   1   37.23  ? 206 ILE B C   1 
ATOM   2667 O  O   . ILE B 2 36  ? -28.144 16.146  7.078   1   36.99  ? 206 ILE B O   1 
ATOM   2668 C  CB  . ILE B 2 36  ? -24.832 15.766  7.795   1   43.9   ? 206 ILE B CB  1 
ATOM   2669 C  CG1 . ILE B 2 36  ? -25.372 14.566  8.524   1   44.43  ? 206 ILE B CG1 1 
ATOM   2670 C  CG2 . ILE B 2 36  ? -23.611 16.327  8.536   1   47.59  ? 206 ILE B CG2 1 
ATOM   2671 C  CD1 . ILE B 2 36  ? -24.313 13.477  8.737   1   45     ? 206 ILE B CD1 1 
ATOM   2672 N  N   . THR B 2 37  ? -26.711 16.435  5.332   1   33.91  ? 207 THR B N   1 
ATOM   2673 C  CA  . THR B 2 37  ? -27.658 16.281  4.241   1   31.44  ? 207 THR B CA  1 
ATOM   2674 C  C   . THR B 2 37  ? -27.162 15.223  3.265   1   31.58  ? 207 THR B C   1 
ATOM   2675 O  O   . THR B 2 37  ? -25.984 14.854  3.286   1   29.82  ? 207 THR B O   1 
ATOM   2676 C  CB  . THR B 2 37  ? -27.797 17.597  3.466   1   31.64  ? 207 THR B CB  1 
ATOM   2677 O  OG1 . THR B 2 37  ? -26.512 17.946  2.945   1   31.73  ? 207 THR B OG1 1 
ATOM   2678 C  CG2 . THR B 2 37  ? -28.319 18.75   4.314   1   30.61  ? 207 THR B CG2 1 
ATOM   2679 N  N   . ASN B 2 38  ? -28.061 14.783  2.379   1   32.42  ? 208 ASN B N   1 
ATOM   2680 C  CA  . ASN B 2 38  ? -27.702 13.844  1.33    1   34.23  ? 208 ASN B CA  1 
ATOM   2681 C  C   . ASN B 2 38  ? -26.544 14.376  0.486   1   33.15  ? 208 ASN B C   1 
ATOM   2682 O  O   . ASN B 2 38  ? -25.656 13.62   0.094   1   34.8   ? 208 ASN B O   1 
ATOM   2683 C  CB  . ASN B 2 38  ? -28.888 13.527  0.424   1   35.85  ? 208 ASN B CB  1 
ATOM   2684 C  CG  . ASN B 2 38  ? -30.003 12.785  1.108   1   36.38  ? 208 ASN B CG  1 
ATOM   2685 O  OD1 . ASN B 2 38  ? -29.78  11.891  1.919   1   36.17  ? 208 ASN B OD1 1 
ATOM   2686 N  ND2 . ASN B 2 38  ? -31.236 13.158  0.793   1   38.26  ? 208 ASN B ND2 1 
ATOM   2687 N  N   . SER B 2 39  ? -26.57  15.683  0.228   1   31.21  ? 209 SER B N   1 
ATOM   2688 C  CA  . SER B 2 39  ? -25.565 16.347  -0.586  1   33.49  ? 209 SER B CA  1 
ATOM   2689 C  C   . SER B 2 39  ? -24.173 16.276  0.042   1   31.06  ? 209 SER B C   1 
ATOM   2690 O  O   . SER B 2 39  ? -23.189 16.059  -0.655  1   31.05  ? 209 SER B O   1 
ATOM   2691 C  CB  . SER B 2 39  ? -25.996 17.794  -0.839  1   33.88  ? 209 SER B CB  1 
ATOM   2692 O  OG  . SER B 2 39  ? -24.896 18.627  -1.167  1   38.58  ? 209 SER B OG  1 
ATOM   2693 N  N   . MET B 2 40  ? -24.103 16.46   1.363   1   31.67  ? 210 MET B N   1 
ATOM   2694 C  CA  . MET B 2 40  ? -22.846 16.343  2.086   1   32.25  ? 210 MET B CA  1 
ATOM   2695 C  C   . MET B 2 40  ? -22.294 14.922  2.021   1   31.77  ? 210 MET B C   1 
ATOM   2696 O  O   . MET B 2 40  ? -21.082 14.72   1.948   1   34.54  ? 210 MET B O   1 
ATOM   2697 C  CB  . MET B 2 40  ? -23.039 16.745  3.547   1   33.15  ? 210 MET B CB  1 
ATOM   2698 C  CG  . MET B 2 40  ? -23.214 18.219  3.72    1   32.2   ? 210 MET B CG  1 
ATOM   2699 S  SD  . MET B 2 40  ? -23.522 18.604  5.44    1   35.42  ? 210 MET B SD  1 
ATOM   2700 C  CE  . MET B 2 40  ? -24.376 20.18   5.294   1   36.82  ? 210 MET B CE  1 
ATOM   2701 N  N   . ARG B 2 41  ? -23.202 13.943  2.064   1   32.43  ? 211 ARG B N   1 
ATOM   2702 C  CA  . ARG B 2 41  ? -22.836 12.536  2.042   1   32.46  ? 211 ARG B CA  1 
ATOM   2703 C  C   . ARG B 2 41  ? -22.322 12.162  0.656   1   32.28  ? 211 ARG B C   1 
ATOM   2704 O  O   . ARG B 2 41  ? -21.382 11.378  0.535   1   33.99  ? 211 ARG B O   1 
ATOM   2705 C  CB  . ARG B 2 41  ? -24.048 11.664  2.435   1   32.15  ? 211 ARG B CB  1 
ATOM   2706 C  CG  . ARG B 2 41  ? -23.844 10.169  2.252   1   31.25  ? 211 ARG B CG  1 
ATOM   2707 C  CD  . ARG B 2 41  ? -25.144 9.42    2.381   1   31.44  ? 211 ARG B CD  1 
ATOM   2708 N  NE  . ARG B 2 41  ? -24.979 7.998   2.1     1   30.91  ? 211 ARG B NE  1 
ATOM   2709 C  CZ  . ARG B 2 41  ? -24.761 7.493   0.894   1   32.81  ? 211 ARG B CZ  1 
ATOM   2710 N  NH1 . ARG B 2 41  ? -24.889 8.231   -0.196  1   33.44  ? 211 ARG B NH1 1 
ATOM   2711 N  NH2 . ARG B 2 41  ? -24.415 6.212   0.777   1   32.59  ? 211 ARG B NH2 1 
ATOM   2712 N  N   . ALA B 2 42  ? -22.965 12.722  -0.378  1   31.97  ? 212 ALA B N   1 
ATOM   2713 C  CA  . ALA B 2 42  ? -22.54  12.552  -1.759  1   31.06  ? 212 ALA B CA  1 
ATOM   2714 C  C   . ALA B 2 42  ? -21.109 13.037  -1.964  1   32.28  ? 212 ALA B C   1 
ATOM   2715 O  O   . ALA B 2 42  ? -20.323 12.377  -2.639  1   35.52  ? 212 ALA B O   1 
ATOM   2716 C  CB  . ALA B 2 42  ? -23.486 13.286  -2.69   1   30.08  ? 212 ALA B CB  1 
ATOM   2717 N  N   . ILE B 2 43  ? -20.781 14.192  -1.372  1   36.32  ? 213 ILE B N   1 
ATOM   2718 C  CA  . ILE B 2 43  ? -19.432 14.73   -1.422  1   33.07  ? 213 ILE B CA  1 
ATOM   2719 C  C   . ILE B 2 43  ? -18.447 13.767  -0.758  1   31.21  ? 213 ILE B C   1 
ATOM   2720 O  O   . ILE B 2 43  ? -17.359 13.526  -1.283  1   28.77  ? 213 ILE B O   1 
ATOM   2721 C  CB  . ILE B 2 43  ? -19.406 16.134  -0.781  1   33.62  ? 213 ILE B CB  1 
ATOM   2722 C  CG1 . ILE B 2 43  ? -20.193 17.151  -1.652  1   34.85  ? 213 ILE B CG1 1 
ATOM   2723 C  CG2 . ILE B 2 43  ? -17.972 16.618  -0.545  1   32.24  ? 213 ILE B CG2 1 
ATOM   2724 C  CD1 . ILE B 2 43  ? -20.415 18.554  -1.008  1   31.82  ? 213 ILE B CD1 1 
ATOM   2725 N  N   . LEU B 2 44  ? -18.843 13.216  0.396   1   27.18  ? 214 LEU B N   1 
ATOM   2726 C  CA  . LEU B 2 44  ? -17.98  12.316  1.144   1   28.48  ? 214 LEU B CA  1 
ATOM   2727 C  C   . LEU B 2 44  ? -17.678 11.046  0.346   1   30.21  ? 214 LEU B C   1 
ATOM   2728 O  O   . LEU B 2 44  ? -16.515 10.668  0.178   1   27.18  ? 214 LEU B O   1 
ATOM   2729 C  CB  . LEU B 2 44  ? -18.624 11.962  2.477   1   30.72  ? 214 LEU B CB  1 
ATOM   2730 C  CG  . LEU B 2 44  ? -17.876 10.947  3.341   1   30.93  ? 214 LEU B CG  1 
ATOM   2731 C  CD1 . LEU B 2 44  ? -16.614 11.524  3.88    1   32.01  ? 214 LEU B CD1 1 
ATOM   2732 C  CD2 . LEU B 2 44  ? -18.763 10.437  4.469   1   29.56  ? 214 LEU B CD2 1 
ATOM   2733 N  N   . VAL B 2 45  ? -18.735 10.405  -0.16   1   27.76  ? 215 VAL B N   1 
ATOM   2734 C  CA  . VAL B 2 45  ? -18.568 9.167   -0.898  1   30.96  ? 215 VAL B CA  1 
ATOM   2735 C  C   . VAL B 2 45  ? -17.732 9.412   -2.157  1   31.83  ? 215 VAL B C   1 
ATOM   2736 O  O   . VAL B 2 45  ? -16.881 8.6     -2.516  1   33.56  ? 215 VAL B O   1 
ATOM   2737 C  CB  . VAL B 2 45  ? -19.931 8.5     -1.206  1   30.72  ? 215 VAL B CB  1 
ATOM   2738 C  CG1 . VAL B 2 45  ? -19.753 7.226   -2.002  1   30.32  ? 215 VAL B CG1 1 
ATOM   2739 C  CG2 . VAL B 2 45  ? -20.714 8.214   0.071   1   30.59  ? 215 VAL B CG2 1 
ATOM   2740 N  N   . ASP B 2 46  ? -17.955 10.55   -2.817  1   31.43  ? 216 ASP B N   1 
ATOM   2741 C  CA  . ASP B 2 46  ? -17.19  10.886  -4.007  1   30.14  ? 216 ASP B CA  1 
ATOM   2742 C  C   . ASP B 2 46  ? -15.702 11.034  -3.708  1   28.45  ? 216 ASP B C   1 
ATOM   2743 O  O   . ASP B 2 46  ? -14.86  10.658  -4.521  1   30.89  ? 216 ASP B O   1 
ATOM   2744 C  CB  . ASP B 2 46  ? -17.708 12.182  -4.617  1   32.85  ? 216 ASP B CB  1 
ATOM   2745 C  CG  . ASP B 2 46  ? -17.041 12.515  -5.918  1   33.25  ? 216 ASP B CG  1 
ATOM   2746 O  OD1 . ASP B 2 46  ? -17.472 11.967  -6.954  1   34.1   ? 216 ASP B OD1 1 
ATOM   2747 O  OD2 . ASP B 2 46  ? -16.041 13.276  -5.893  1   32.47  ? 216 ASP B OD2 1 
ATOM   2748 N  N   . TRP B 2 47  ? -15.395 11.632  -2.552  1   28.13  ? 217 TRP B N   1 
ATOM   2749 C  CA  . TRP B 2 47  ? -14.034 11.725  -2.051  1   27.51  ? 217 TRP B CA  1 
ATOM   2750 C  C   . TRP B 2 47  ? -13.446 10.346  -1.731  1   28.39  ? 217 TRP B C   1 
ATOM   2751 O  O   . TRP B 2 47  ? -12.292 10.074  -2.041  1   30.68  ? 217 TRP B O   1 
ATOM   2752 C  CB  . TRP B 2 47  ? -14.015 12.673  -0.839  1   28.71  ? 217 TRP B CB  1 
ATOM   2753 C  CG  . TRP B 2 47  ? -12.705 12.727  -0.125  1   28.94  ? 217 TRP B CG  1 
ATOM   2754 C  CD1 . TRP B 2 47  ? -11.571 13.348  -0.541  1   27.77  ? 217 TRP B CD1 1 
ATOM   2755 C  CD2 . TRP B 2 47  ? -12.382 12.091  1.114   1   27.96  ? 217 TRP B CD2 1 
ATOM   2756 N  NE1 . TRP B 2 47  ? -10.56  13.147  0.37    1   27.8   ? 217 TRP B NE1 1 
ATOM   2757 C  CE2 . TRP B 2 47  ? -11.032 12.376  1.394   1   29.08  ? 217 TRP B CE2 1 
ATOM   2758 C  CE3 . TRP B 2 47  ? -13.095 11.297  2.005   1   31.11  ? 217 TRP B CE3 1 
ATOM   2759 C  CZ2 . TRP B 2 47  ? -10.393 11.91   2.538   1   31.79  ? 217 TRP B CZ2 1 
ATOM   2760 C  CZ3 . TRP B 2 47  ? -12.455 10.828  3.136   1   32.98  ? 217 TRP B CZ3 1 
ATOM   2761 C  CH2 . TRP B 2 47  ? -11.123 11.14   3.395   1   30.7   ? 217 TRP B CH2 1 
ATOM   2762 N  N   . LEU B 2 48  ? -14.248 9.454   -1.138  1   30.44  ? 218 LEU B N   1 
ATOM   2763 C  CA  . LEU B 2 48  ? -13.798 8.1     -0.853  1   31.83  ? 218 LEU B CA  1 
ATOM   2764 C  C   . LEU B 2 48  ? -13.511 7.313   -2.13   1   32.92  ? 218 LEU B C   1 
ATOM   2765 O  O   . LEU B 2 48  ? -12.65  6.437   -2.129  1   31.32  ? 218 LEU B O   1 
ATOM   2766 C  CB  . LEU B 2 48  ? -14.833 7.35    0.005   1   33.39  ? 218 LEU B CB  1 
ATOM   2767 C  CG  . LEU B 2 48  ? -14.963 7.824   1.456   1   32.96  ? 218 LEU B CG  1 
ATOM   2768 C  CD1 . LEU B 2 48  ? -16.015 7.081   2.161   1   31.84  ? 218 LEU B CD1 1 
ATOM   2769 C  CD2 . LEU B 2 48  ? -13.634 7.685   2.208   1   35.16  ? 218 LEU B CD2 1 
ATOM   2770 N  N   . VAL B 2 49  ? -14.214 7.643   -3.219  1   31.36  ? 219 VAL B N   1 
ATOM   2771 C  CA  . VAL B 2 49  ? -13.895 7.083   -4.526  1   32.29  ? 219 VAL B CA  1 
ATOM   2772 C  C   . VAL B 2 49  ? -12.487 7.498   -4.959  1   33.98  ? 219 VAL B C   1 
ATOM   2773 O  O   . VAL B 2 49  ? -11.695 6.655   -5.369  1   29.7   ? 219 VAL B O   1 
ATOM   2774 C  CB  . VAL B 2 49  ? -14.962 7.462   -5.57   1   32.86  ? 219 VAL B CB  1 
ATOM   2775 C  CG1 . VAL B 2 49  ? -14.49  7.183   -6.976  1   35.26  ? 219 VAL B CG1 1 
ATOM   2776 C  CG2 . VAL B 2 49  ? -16.274 6.742   -5.294  1   32.82  ? 219 VAL B CG2 1 
ATOM   2777 N  N   . GLU B 2 50  ? -12.179 8.796   -4.857  1   37.28  ? 220 GLU B N   1 
ATOM   2778 C  CA  . GLU B 2 50  ? -10.848 9.298   -5.158  1   37.54  ? 220 GLU B CA  1 
ATOM   2779 C  C   . GLU B 2 50  ? -9.785  8.63    -4.291  1   35.26  ? 220 GLU B C   1 
ATOM   2780 O  O   . GLU B 2 50  ? -8.738  8.231   -4.781  1   33.18  ? 220 GLU B O   1 
ATOM   2781 C  CB  . GLU B 2 50  ? -10.752 10.809  -4.928  1   40.97  ? 220 GLU B CB  1 
ATOM   2782 C  CG  . GLU B 2 50  ? -11.347 11.648  -6.033  1   47.64  ? 220 GLU B CG  1 
ATOM   2783 C  CD  . GLU B 2 50  ? -11.155 13.141  -5.854  1   48.97  ? 220 GLU B CD  1 
ATOM   2784 O  OE1 . GLU B 2 50  ? -11.045 13.603  -4.692  1   50.2   ? 220 GLU B OE1 1 
ATOM   2785 O  OE2 . GLU B 2 50  ? -11.072 13.841  -6.889  1   50.11  ? 220 GLU B OE2 1 
ATOM   2786 N  N   . VAL B 2 51  ? -10.044 8.555   -2.986  1   32.1   ? 221 VAL B N   1 
ATOM   2787 C  CA  . VAL B 2 51  ? -9.11   7.915   -2.077  1   32.52  ? 221 VAL B CA  1 
ATOM   2788 C  C   . VAL B 2 51  ? -8.849  6.479   -2.532  1   30.55  ? 221 VAL B C   1 
ATOM   2789 O  O   . VAL B 2 51  ? -7.694  6.055   -2.618  1   30.78  ? 221 VAL B O   1 
ATOM   2790 C  CB  . VAL B 2 51  ? -9.609  8.005   -0.626  1   32.38  ? 221 VAL B CB  1 
ATOM   2791 C  CG1 . VAL B 2 51  ? -8.792  7.102   0.306   1   32.19  ? 221 VAL B CG1 1 
ATOM   2792 C  CG2 . VAL B 2 51  ? -9.59   9.45    -0.152  1   32.24  ? 221 VAL B CG2 1 
ATOM   2793 N  N   . GLY B 2 52  ? -9.929  5.756   -2.85   1   30.68  ? 222 GLY B N   1 
ATOM   2794 C  CA  . GLY B 2 52  ? -9.834  4.419   -3.415  1   33.79  ? 222 GLY B CA  1 
ATOM   2795 C  C   . GLY B 2 52  ? -8.916  4.329   -4.633  1   38.05  ? 222 GLY B C   1 
ATOM   2796 O  O   . GLY B 2 52  ? -8.171  3.365   -4.768  1   42.27  ? 222 GLY B O   1 
ATOM   2797 N  N   . GLU B 2 53  ? -8.975  5.346   -5.507  1   41.48  ? 223 GLU B N   1 
ATOM   2798 C  CA  . GLU B 2 53  ? -8.139  5.436   -6.695  1   42.11  ? 223 GLU B CA  1 
ATOM   2799 C  C   . GLU B 2 53  ? -6.691  5.795   -6.389  1   42.1   ? 223 GLU B C   1 
ATOM   2800 O  O   . GLU B 2 53  ? -5.77   5.146   -6.873  1   39.7   ? 223 GLU B O   1 
ATOM   2801 C  CB  . GLU B 2 53  ? -8.729  6.482   -7.661  1   46.3   ? 223 GLU B CB  1 
ATOM   2802 C  CG  . GLU B 2 53  ? -9.912  5.919   -8.388  1   51.2   ? 223 GLU B CG  1 
ATOM   2803 C  CD  . GLU B 2 53  ? -9.477  4.726   -9.211  1   56.68  ? 223 GLU B CD  1 
ATOM   2804 O  OE1 . GLU B 2 53  ? -8.755  4.957   -10.208 1   68.78  ? 223 GLU B OE1 1 
ATOM   2805 O  OE2 . GLU B 2 53  ? -9.786  3.571   -8.832  1   57.37  ? 223 GLU B OE2 1 
ATOM   2806 N  N   . GLU B 2 54  ? -6.51   6.85    -5.591  1   43.76  ? 224 GLU B N   1 
ATOM   2807 C  CA  . GLU B 2 54  ? -5.209  7.249   -5.088  1   42.82  ? 224 GLU B CA  1 
ATOM   2808 C  C   . GLU B 2 54  ? -4.404  6.084   -4.501  1   41.11  ? 224 GLU B C   1 
ATOM   2809 O  O   . GLU B 2 54  ? -3.194  6.026   -4.685  1   41.28  ? 224 GLU B O   1 
ATOM   2810 C  CB  . GLU B 2 54  ? -5.434  8.357   -4.039  1   45.78  ? 224 GLU B CB  1 
ATOM   2811 C  CG  . GLU B 2 54  ? -4.207  8.796   -3.258  1   51.03  ? 224 GLU B CG  1 
ATOM   2812 C  CD  . GLU B 2 54  ? -3.133  9.49    -4.071  1   54.72  ? 224 GLU B CD  1 
ATOM   2813 O  OE1 . GLU B 2 54  ? -3.392  9.758   -5.264  1   60.7   ? 224 GLU B OE1 1 
ATOM   2814 O  OE2 . GLU B 2 54  ? -2.022  9.713   -3.537  1   59.42  ? 224 GLU B OE2 1 
ATOM   2815 N  N   . TYR B 2 55  ? -5.069  5.169   -3.783  1   37.04  ? 225 TYR B N   1 
ATOM   2816 C  CA  . TYR B 2 55  ? -4.387  4.07    -3.118  1   35.85  ? 225 TYR B CA  1 
ATOM   2817 C  C   . TYR B 2 55  ? -4.61   2.711   -3.774  1   36.43  ? 225 TYR B C   1 
ATOM   2818 O  O   . TYR B 2 55  ? -4.161  1.694   -3.254  1   39.55  ? 225 TYR B O   1 
ATOM   2819 C  CB  . TYR B 2 55  ? -4.796  4.039   -1.634  1   36.6   ? 225 TYR B CB  1 
ATOM   2820 C  CG  . TYR B 2 55  ? -4.179  5.196   -0.876  1   38.79  ? 225 TYR B CG  1 
ATOM   2821 C  CD1 . TYR B 2 55  ? -2.842  5.173   -0.493  1   38.16  ? 225 TYR B CD1 1 
ATOM   2822 C  CD2 . TYR B 2 55  ? -4.904  6.348   -0.622  1   40.3   ? 225 TYR B CD2 1 
ATOM   2823 C  CE1 . TYR B 2 55  ? -2.264  6.252   0.174   1   40.79  ? 225 TYR B CE1 1 
ATOM   2824 C  CE2 . TYR B 2 55  ? -4.332  7.433   0.031   1   41.66  ? 225 TYR B CE2 1 
ATOM   2825 C  CZ  . TYR B 2 55  ? -3.016  7.379   0.438   1   38.45  ? 225 TYR B CZ  1 
ATOM   2826 O  OH  . TYR B 2 55  ? -2.472  8.464   1.074   1   39.05  ? 225 TYR B OH  1 
ATOM   2827 N  N   . LYS B 2 56  ? -5.288  2.711   -4.925  1   40.19  ? 226 LYS B N   1 
ATOM   2828 C  CA  . LYS B 2 56  ? -5.544  1.5     -5.691  1   44.01  ? 226 LYS B CA  1 
ATOM   2829 C  C   . LYS B 2 56  ? -6.171  0.431   -4.798  1   42.24  ? 226 LYS B C   1 
ATOM   2830 O  O   . LYS B 2 56  ? -5.718  -0.711  -4.752  1   39.65  ? 226 LYS B O   1 
ATOM   2831 C  CB  . LYS B 2 56  ? -4.261  0.994   -6.353  1   46.2   ? 226 LYS B CB  1 
ATOM   2832 C  CG  . LYS B 2 56  ? -3.561  2.053   -7.201  1   52.64  ? 226 LYS B CG  1 
ATOM   2833 C  CD  . LYS B 2 56  ? -2.507  1.469   -8.148  1   62.52  ? 226 LYS B CD  1 
ATOM   2834 C  CE  . LYS B 2 56  ? -1.383  0.762   -7.417  1   65.75  ? 226 LYS B CE  1 
ATOM   2835 N  NZ  . LYS B 2 56  ? -0.684  -0.203  -8.297  1   68.98  ? 226 LYS B NZ  1 
ATOM   2836 N  N   . LEU B 2 57  ? -7.232  0.837   -4.093  1   38.15  ? 227 LEU B N   1 
ATOM   2837 C  CA  . LEU B 2 57  ? -7.974  -0.055  -3.23   1   34.61  ? 227 LEU B CA  1 
ATOM   2838 C  C   . LEU B 2 57  ? -8.964  -0.811  -4.102  1   33.82  ? 227 LEU B C   1 
ATOM   2839 O  O   . LEU B 2 57  ? -9.316  -0.348  -5.184  1   35.47  ? 227 LEU B O   1 
ATOM   2840 C  CB  . LEU B 2 57  ? -8.716  0.721   -2.137  1   34.22  ? 227 LEU B CB  1 
ATOM   2841 C  CG  . LEU B 2 57  ? -7.858  1.621   -1.261  1   35.5   ? 227 LEU B CG  1 
ATOM   2842 C  CD1 . LEU B 2 57  ? -8.69   2.305   -0.222  1   36.18  ? 227 LEU B CD1 1 
ATOM   2843 C  CD2 . LEU B 2 57  ? -6.739  0.847   -0.585  1   35.55  ? 227 LEU B CD2 1 
ATOM   2844 N  N   . GLN B 2 58  ? -9.398  -1.97   -3.603  1   31.72  ? 228 GLN B N   1 
ATOM   2845 C  CA  . GLN B 2 58  ? -10.476 -2.73   -4.202  1   32.99  ? 228 GLN B CA  1 
ATOM   2846 C  C   . GLN B 2 58  ? -11.775 -1.934  -4.168  1   33.03  ? 228 GLN B C   1 
ATOM   2847 O  O   . GLN B 2 58  ? -12.021 -1.167  -3.242  1   31.69  ? 228 GLN B O   1 
ATOM   2848 C  CB  . GLN B 2 58  ? -10.684 -4.056  -3.433  1   32.44  ? 228 GLN B CB  1 
ATOM   2849 C  CG  . GLN B 2 58  ? -9.505  -4.981  -3.454  1   33.74  ? 228 GLN B CG  1 
ATOM   2850 C  CD  . GLN B 2 58  ? -9.26   -5.492  -4.832  1   35.63  ? 228 GLN B CD  1 
ATOM   2851 O  OE1 . GLN B 2 58  ? -8.198  -5.29   -5.4    1   37.39  ? 228 GLN B OE1 1 
ATOM   2852 N  NE2 . GLN B 2 58  ? -10.254 -6.138  -5.403  1   36.83  ? 228 GLN B NE2 1 
ATOM   2853 N  N   . ASN B 2 59  ? -12.621 -2.16   -5.174  1   35.1   ? 229 ASN B N   1 
ATOM   2854 C  CA  . ASN B 2 59  ? -13.954 -1.587  -5.186  1   34.95  ? 229 ASN B CA  1 
ATOM   2855 C  C   . ASN B 2 59  ? -14.79  -2.111  -4.027  1   35.4   ? 229 ASN B C   1 
ATOM   2856 O  O   . ASN B 2 59  ? -15.627 -1.382  -3.501  1   36.05  ? 229 ASN B O   1 
ATOM   2857 C  CB  . ASN B 2 59  ? -14.656 -1.894  -6.486  1   37.37  ? 229 ASN B CB  1 
ATOM   2858 C  CG  . ASN B 2 59  ? -14.085 -1.167  -7.653  1   35.14  ? 229 ASN B CG  1 
ATOM   2859 O  OD1 . ASN B 2 59  ? -13.386 -0.173  -7.519  1   32.17  ? 229 ASN B OD1 1 
ATOM   2860 N  ND2 . ASN B 2 59  ? -14.404 -1.657  -8.818  1   36.94  ? 229 ASN B ND2 1 
ATOM   2861 N  N   . GLU B 2 60  ? -14.563 -3.378  -3.654  1   33.27  ? 230 GLU B N   1 
ATOM   2862 C  CA  . GLU B 2 60  ? -15.265 -3.986  -2.536  1   30.09  ? 230 GLU B CA  1 
ATOM   2863 C  C   . GLU B 2 60  ? -15.01  -3.182  -1.264  1   29.03  ? 230 GLU B C   1 
ATOM   2864 O  O   . GLU B 2 60  ? -15.922 -2.992  -0.463  1   27.88  ? 230 GLU B O   1 
ATOM   2865 C  CB  . GLU B 2 60  ? -14.839 -5.454  -2.358  1   30.21  ? 230 GLU B CB  1 
ATOM   2866 C  CG  . GLU B 2 60  ? -15.412 -6.156  -1.135  1   30.58  ? 230 GLU B CG  1 
ATOM   2867 C  CD  . GLU B 2 60  ? -16.902 -6.419  -1.167  1   33.02  ? 230 GLU B CD  1 
ATOM   2868 O  OE1 . GLU B 2 60  ? -17.536 -6.147  -2.211  1   32.49  ? 230 GLU B OE1 1 
ATOM   2869 O  OE2 . GLU B 2 60  ? -17.433 -6.909  -0.147  1   32.72  ? 230 GLU B OE2 1 
ATOM   2870 N  N   . THR B 2 61  ? -13.77  -2.702  -1.098  1   31.12  ? 231 THR B N   1 
ATOM   2871 C  CA  . THR B 2 61  ? -13.404 -1.902  0.06    1   31.53  ? 231 THR B CA  1 
ATOM   2872 C  C   . THR B 2 61  ? -14.264 -0.64   0.147   1   30.79  ? 231 THR B C   1 
ATOM   2873 O  O   . THR B 2 61  ? -14.751 -0.299  1.225   1   27.43  ? 231 THR B O   1 
ATOM   2874 C  CB  . THR B 2 61  ? -11.918 -1.56   0.025   1   33.02  ? 231 THR B CB  1 
ATOM   2875 O  OG1 . THR B 2 61  ? -11.156 -2.753  -0.096  1   28.97  ? 231 THR B OG1 1 
ATOM   2876 C  CG2 . THR B 2 61  ? -11.476 -0.783  1.267   1   33.72  ? 231 THR B CG2 1 
ATOM   2877 N  N   . LEU B 2 62  ? -14.433 0.041   -0.996  1   30.35  ? 232 LEU B N   1 
ATOM   2878 C  CA  . LEU B 2 62  ? -15.248 1.242   -1.082  1   31.47  ? 232 LEU B CA  1 
ATOM   2879 C  C   . LEU B 2 62  ? -16.69  0.959   -0.675  1   31.09  ? 232 LEU B C   1 
ATOM   2880 O  O   . LEU B 2 62  ? -17.254 1.696   0.123   1   29.51  ? 232 LEU B O   1 
ATOM   2881 C  CB  . LEU B 2 62  ? -15.207 1.812   -2.511  1   33.93  ? 232 LEU B CB  1 
ATOM   2882 C  CG  . LEU B 2 62  ? -16.21  2.943   -2.831  1   36.58  ? 232 LEU B CG  1 
ATOM   2883 C  CD1 . LEU B 2 62  ? -15.868 4.229   -2.112  1   37.59  ? 232 LEU B CD1 1 
ATOM   2884 C  CD2 . LEU B 2 62  ? -16.256 3.203   -4.281  1   37.07  ? 232 LEU B CD2 1 
ATOM   2885 N  N   . HIS B 2 63  ? -17.274 -0.113  -1.223  1   29.81  ? 233 HIS B N   1 
ATOM   2886 C  CA  . HIS B 2 63  ? -18.638 -0.493  -0.885  1   30.05  ? 233 HIS B CA  1 
ATOM   2887 C  C   . HIS B 2 63  ? -18.807 -0.801  0.611   1   30     ? 233 HIS B C   1 
ATOM   2888 O  O   . HIS B 2 63  ? -19.797 -0.409  1.217   1   27.42  ? 233 HIS B O   1 
ATOM   2889 C  CB  . HIS B 2 63  ? -19.103 -1.692  -1.732  1   29.55  ? 233 HIS B CB  1 
ATOM   2890 C  CG  . HIS B 2 63  ? -19.492 -1.379  -3.147  1   32.7   ? 233 HIS B CG  1 
ATOM   2891 N  ND1 . HIS B 2 63  ? -18.544 -1.08   -4.119  1   35.07  ? 233 HIS B ND1 1 
ATOM   2892 C  CD2 . HIS B 2 63  ? -20.713 -1.37   -3.723  1   31.47  ? 233 HIS B CD2 1 
ATOM   2893 C  CE1 . HIS B 2 63  ? -19.23  -0.869  -5.236  1   32.24  ? 233 HIS B CE1 1 
ATOM   2894 N  NE2 . HIS B 2 63  ? -20.539 -1.051  -5.038  1   32.5   ? 233 HIS B NE2 1 
ATOM   2895 N  N   . LEU B 2 64  ? -17.839 -1.503  1.206   1   28.21  ? 234 LEU B N   1 
ATOM   2896 C  CA  . LEU B 2 64  ? -17.873 -1.78   2.63    1   30.82  ? 234 LEU B CA  1 
ATOM   2897 C  C   . LEU B 2 64  ? -17.873 -0.484  3.445   1   31.91  ? 234 LEU B C   1 
ATOM   2898 O  O   . LEU B 2 64  ? -18.691 -0.3    4.344   1   30.74  ? 234 LEU B O   1 
ATOM   2899 C  CB  . LEU B 2 64  ? -16.681 -2.662  3.012   1   30.09  ? 234 LEU B CB  1 
ATOM   2900 C  CG  . LEU B 2 64  ? -16.754 -4.093  2.533   1   28.6   ? 234 LEU B CG  1 
ATOM   2901 C  CD1 . LEU B 2 64  ? -15.429 -4.803  2.755   1   28.78  ? 234 LEU B CD1 1 
ATOM   2902 C  CD2 . LEU B 2 64  ? -17.878 -4.862  3.218   1   28.5   ? 234 LEU B CD2 1 
ATOM   2903 N  N   . ALA B 2 65  ? -16.969 0.438   3.108   1   33.54  ? 235 ALA B N   1 
ATOM   2904 C  CA  . ALA B 2 65  ? -16.874 1.692   3.836   1   31.36  ? 235 ALA B CA  1 
ATOM   2905 C  C   . ALA B 2 65  ? -18.202 2.455   3.835   1   30.11  ? 235 ALA B C   1 
ATOM   2906 O  O   . ALA B 2 65  ? -18.62  2.99    4.865   1   31.4   ? 235 ALA B O   1 
ATOM   2907 C  CB  . ALA B 2 65  ? -15.761 2.548   3.256   1   29.84  ? 235 ALA B CB  1 
ATOM   2908 N  N   . VAL B 2 66  ? -18.858 2.514   2.672   1   28.22  ? 236 VAL B N   1 
ATOM   2909 C  CA  . VAL B 2 66  ? -20.123 3.22    2.542   1   28.94  ? 236 VAL B CA  1 
ATOM   2910 C  C   . VAL B 2 66  ? -21.182 2.547   3.42    1   30.34  ? 236 VAL B C   1 
ATOM   2911 O  O   . VAL B 2 66  ? -21.98  3.227   4.058   1   34.17  ? 236 VAL B O   1 
ATOM   2912 C  CB  . VAL B 2 66  ? -20.573 3.314   1.071   1   30.21  ? 236 VAL B CB  1 
ATOM   2913 C  CG1 . VAL B 2 66  ? -21.948 3.985   0.957   1   33.12  ? 236 VAL B CG1 1 
ATOM   2914 C  CG2 . VAL B 2 66  ? -19.549 4.054   0.212   1   30.23  ? 236 VAL B CG2 1 
ATOM   2915 N  N   . ASN B 2 67  ? -21.179 1.21    3.462   1   28.64  ? 237 ASN B N   1 
ATOM   2916 C  CA  . ASN B 2 67  ? -22.079 0.473   4.34    1   29.54  ? 237 ASN B CA  1 
ATOM   2917 C  C   . ASN B 2 67  ? -21.858 0.846   5.806   1   26.55  ? 237 ASN B C   1 
ATOM   2918 O  O   . ASN B 2 67  ? -22.817 1.026   6.551   1   24.79  ? 237 ASN B O   1 
ATOM   2919 C  CB  . ASN B 2 67  ? -21.912 -1.054  4.143   1   29.65  ? 237 ASN B CB  1 
ATOM   2920 C  CG  . ASN B 2 67  ? -22.726 -1.862  5.1     1   32.99  ? 237 ASN B CG  1 
ATOM   2921 O  OD1 . ASN B 2 67  ? -22.253 -2.34   6.129   1   36.95  ? 237 ASN B OD1 1 
ATOM   2922 N  ND2 . ASN B 2 67  ? -23.993 -1.989  4.829   1   35.75  ? 237 ASN B ND2 1 
ATOM   2923 N  N   . TYR B 2 68  ? -20.586 0.961   6.21    1   26.31  ? 238 TYR B N   1 
ATOM   2924 C  CA  . TYR B 2 68  ? -20.242 1.258   7.593   1   27.11  ? 238 TYR B CA  1 
ATOM   2925 C  C   . TYR B 2 68  ? -20.723 2.656   7.975   1   29.33  ? 238 TYR B C   1 
ATOM   2926 O  O   . TYR B 2 68  ? -21.25  2.857   9.074   1   28.83  ? 238 TYR B O   1 
ATOM   2927 C  CB  . TYR B 2 68  ? -18.721 1.144   7.841   1   28.87  ? 238 TYR B CB  1 
ATOM   2928 C  CG  . TYR B 2 68  ? -18.101 -0.225  7.563   1   28.66  ? 238 TYR B CG  1 
ATOM   2929 C  CD1 . TYR B 2 68  ? -18.891 -1.351  7.384   1   26.72  ? 238 TYR B CD1 1 
ATOM   2930 C  CD2 . TYR B 2 68  ? -16.731 -0.378  7.462   1   26.96  ? 238 TYR B CD2 1 
ATOM   2931 C  CE1 . TYR B 2 68  ? -18.325 -2.598  7.13    1   26.07  ? 238 TYR B CE1 1 
ATOM   2932 C  CE2 . TYR B 2 68  ? -16.158 -1.615  7.2     1   26.32  ? 238 TYR B CE2 1 
ATOM   2933 C  CZ  . TYR B 2 68  ? -16.956 -2.725  7.037   1   26.13  ? 238 TYR B CZ  1 
ATOM   2934 O  OH  . TYR B 2 68  ? -16.371 -3.948  6.761   1   27.26  ? 238 TYR B OH  1 
ATOM   2935 N  N   . ILE B 2 69  ? -20.533 3.606   7.048   1   30.77  ? 239 ILE B N   1 
ATOM   2936 C  CA  . ILE B 2 69  ? -20.912 4.99    7.265   1   31.42  ? 239 ILE B CA  1 
ATOM   2937 C  C   . ILE B 2 69  ? -22.423 5.086   7.45    1   29.99  ? 239 ILE B C   1 
ATOM   2938 O  O   . ILE B 2 69  ? -22.893 5.682   8.419   1   26.57  ? 239 ILE B O   1 
ATOM   2939 C  CB  . ILE B 2 69  ? -20.414 5.886   6.093   1   32.33  ? 239 ILE B CB  1 
ATOM   2940 C  CG1 . ILE B 2 69  ? -18.885 5.975   6.057   1   34.64  ? 239 ILE B CG1 1 
ATOM   2941 C  CG2 . ILE B 2 69  ? -21.032 7.27    6.16    1   32.1   ? 239 ILE B CG2 1 
ATOM   2942 C  CD1 . ILE B 2 69  ? -18.313 6.438   4.705   1   34.7   ? 239 ILE B CD1 1 
ATOM   2943 N  N   . ASP B 2 70  ? -23.168 4.488   6.512   1   27.39  ? 240 ASP B N   1 
ATOM   2944 C  CA  . ASP B 2 70  ? -24.618 4.6     6.52    1   29.26  ? 240 ASP B CA  1 
ATOM   2945 C  C   . ASP B 2 70  ? -25.239 3.949   7.752   1   28.76  ? 240 ASP B C   1 
ATOM   2946 O  O   . ASP B 2 70  ? -26.207 4.475   8.284   1   30.44  ? 240 ASP B O   1 
ATOM   2947 C  CB  . ASP B 2 70  ? -25.223 4.028   5.226   1   29.71  ? 240 ASP B CB  1 
ATOM   2948 C  CG  . ASP B 2 70  ? -25.027 4.93    4       1   31.22  ? 240 ASP B CG  1 
ATOM   2949 O  OD1 . ASP B 2 70  ? -24.886 6.158   4.179   1   33.78  ? 240 ASP B OD1 1 
ATOM   2950 O  OD2 . ASP B 2 70  ? -24.993 4.4     2.863   1   27.67  ? 240 ASP B OD2 1 
ATOM   2951 N  N   . ARG B 2 71  ? -24.671 2.829   8.22    1   30.35  ? 241 ARG B N   1 
ATOM   2952 C  CA  . ARG B 2 71  ? -25.144 2.211   9.452   1   32.45  ? 241 ARG B CA  1 
ATOM   2953 C  C   . ARG B 2 71  ? -24.802 3.084   10.659  1   29.85  ? 241 ARG B C   1 
ATOM   2954 O  O   . ARG B 2 71  ? -25.612 3.227   11.575  1   31.6   ? 241 ARG B O   1 
ATOM   2955 C  CB  . ARG B 2 71  ? -24.561 0.798   9.651   1   33.25  ? 241 ARG B CB  1 
ATOM   2956 C  CG  . ARG B 2 71  ? -25.224 -0.27   8.782   1   33.98  ? 241 ARG B CG  1 
ATOM   2957 C  CD  . ARG B 2 71  ? -24.269 -1.418  8.445   1   34.4   ? 241 ARG B CD  1 
ATOM   2958 N  NE  . ARG B 2 71  ? -24.097 -2.317  9.577   1   34.41  ? 241 ARG B NE  1 
ATOM   2959 C  CZ  . ARG B 2 71  ? -23.103 -3.186  9.709   1   31.7   ? 241 ARG B CZ  1 
ATOM   2960 N  NH1 . ARG B 2 71  ? -22.19  -3.349  8.769   1   33.2   ? 241 ARG B NH1 1 
ATOM   2961 N  NH2 . ARG B 2 71  ? -23.015 -3.902  10.82   1   33.45  ? 241 ARG B NH2 1 
ATOM   2962 N  N   . PHE B 2 72  ? -23.6   3.668   10.65   1   26.46  ? 242 PHE B N   1 
ATOM   2963 C  CA  . PHE B 2 72  ? -23.162 4.506   11.753  1   27.4   ? 242 PHE B CA  1 
ATOM   2964 C  C   . PHE B 2 72  ? -24.066 5.731   11.881  1   28.69  ? 242 PHE B C   1 
ATOM   2965 O  O   . PHE B 2 72  ? -24.559 6.028   12.968  1   26.56  ? 242 PHE B O   1 
ATOM   2966 C  CB  . PHE B 2 72  ? -21.702 4.899   11.564  1   26.12  ? 242 PHE B CB  1 
ATOM   2967 C  CG  . PHE B 2 72  ? -21.117 5.683   12.693  1   25.82  ? 242 PHE B CG  1 
ATOM   2968 C  CD1 . PHE B 2 72  ? -21.222 7.062   12.725  1   25.65  ? 242 PHE B CD1 1 
ATOM   2969 C  CD2 . PHE B 2 72  ? -20.466 5.047   13.733  1   26.23  ? 242 PHE B CD2 1 
ATOM   2970 C  CE1 . PHE B 2 72  ? -20.667 7.792   13.774  1   25.71  ? 242 PHE B CE1 1 
ATOM   2971 C  CE2 . PHE B 2 72  ? -19.944 5.778   14.797  1   27.3   ? 242 PHE B CE2 1 
ATOM   2972 C  CZ  . PHE B 2 72  ? -20.033 7.146   14.804  1   25.77  ? 242 PHE B CZ  1 
ATOM   2973 N  N   . LEU B 2 73  ? -24.289 6.416   10.752  1   29.44  ? 243 LEU B N   1 
ATOM   2974 C  CA  . LEU B 2 73  ? -25.136 7.593   10.714  1   30.14  ? 243 LEU B CA  1 
ATOM   2975 C  C   . LEU B 2 73  ? -26.616 7.282   10.95   1   29.94  ? 243 LEU B C   1 
ATOM   2976 O  O   . LEU B 2 73  ? -27.398 8.201   11.167  1   28.86  ? 243 LEU B O   1 
ATOM   2977 C  CB  . LEU B 2 73  ? -24.977 8.318   9.365   1   30.35  ? 243 LEU B CB  1 
ATOM   2978 C  CG  . LEU B 2 73  ? -23.597 8.882   9.06    1   30.58  ? 243 LEU B CG  1 
ATOM   2979 C  CD1 . LEU B 2 73  ? -23.602 9.584   7.775   1   29.03  ? 243 LEU B CD1 1 
ATOM   2980 C  CD2 . LEU B 2 73  ? -23.096 9.828   10.174  1   33.24  ? 243 LEU B CD2 1 
ATOM   2981 N  N   . SER B 2 74  ? -26.993 6       10.911  1   28.9   ? 244 SER B N   1 
ATOM   2982 C  CA  . SER B 2 74  ? -28.326 5.576   11.302  1   29.79  ? 244 SER B CA  1 
ATOM   2983 C  C   . SER B 2 74  ? -28.581 5.619   12.814  1   29.93  ? 244 SER B C   1 
ATOM   2984 O  O   . SER B 2 74  ? -29.737 5.697   13.235  1   25.31  ? 244 SER B O   1 
ATOM   2985 C  CB  . SER B 2 74  ? -28.607 4.173   10.767  1   29.96  ? 244 SER B CB  1 
ATOM   2986 O  OG  . SER B 2 74  ? -28.577 4.147   9.345   1   29.58  ? 244 SER B OG  1 
ATOM   2987 N  N   . SER B 2 75  ? -27.523 5.58    13.641  1   29.36  ? 245 SER B N   1 
ATOM   2988 C  CA  . SER B 2 75  ? -27.738 5.765   15.071  1   30.55  ? 245 SER B CA  1 
ATOM   2989 C  C   . SER B 2 75  ? -26.963 6.896   15.739  1   31.27  ? 245 SER B C   1 
ATOM   2990 O  O   . SER B 2 75  ? -27.249 7.22    16.889  1   30.21  ? 245 SER B O   1 
ATOM   2991 C  CB  . SER B 2 75  ? -27.504 4.47    15.84   1   29.02  ? 245 SER B CB  1 
ATOM   2992 O  OG  . SER B 2 75  ? -26.133 4.161   15.891  1   31.29  ? 245 SER B OG  1 
ATOM   2993 N  N   . MET B 2 76  ? -26.017 7.525   15.027  1   31.52  ? 246 MET B N   1 
ATOM   2994 C  CA  . MET B 2 76  ? -25.199 8.576   15.623  1   29.84  ? 246 MET B CA  1 
ATOM   2995 C  C   . MET B 2 76  ? -25.339 9.886   14.847  1   29.99  ? 246 MET B C   1 
ATOM   2996 O  O   . MET B 2 76  ? -25.102 9.925   13.64   1   31.39  ? 246 MET B O   1 
ATOM   2997 C  CB  . MET B 2 76  ? -23.731 8.17    15.643  1   26.72  ? 246 MET B CB  1 
ATOM   2998 C  CG  . MET B 2 76  ? -23.471 6.826   16.279  1   26.34  ? 246 MET B CG  1 
ATOM   2999 S  SD  . MET B 2 76  ? -23.681 6.743   18.047  1   27.49  ? 246 MET B SD  1 
ATOM   3000 C  CE  . MET B 2 76  ? -22.415 7.763   18.611  1   27.44  ? 246 MET B CE  1 
ATOM   3001 N  N   . SER B 2 77  ? -25.763 10.939  15.552  1   27.58  ? 247 SER B N   1 
ATOM   3002 C  CA  . SER B 2 77  ? -25.788 12.276  14.986  1   30.84  ? 247 SER B CA  1 
ATOM   3003 C  C   . SER B 2 77  ? -24.354 12.777  14.868  1   31     ? 247 SER B C   1 
ATOM   3004 O  O   . SER B 2 77  ? -23.563 12.605  15.792  1   28.39  ? 247 SER B O   1 
ATOM   3005 C  CB  . SER B 2 77  ? -26.604 13.243  15.841  1   31.53  ? 247 SER B CB  1 
ATOM   3006 O  OG  . SER B 2 77  ? -27.938 12.793  15.989  1   32.33  ? 247 SER B OG  1 
ATOM   3007 N  N   . VAL B 2 78  ? -24.038 13.397  13.725  1   33.06  ? 248 VAL B N   1 
ATOM   3008 C  CA  . VAL B 2 78  ? -22.694 13.869  13.44   1   30.8   ? 248 VAL B CA  1 
ATOM   3009 C  C   . VAL B 2 78  ? -22.753 15.289  12.888  1   29.96  ? 248 VAL B C   1 
ATOM   3010 O  O   . VAL B 2 78  ? -23.558 15.57   12.005  1   31.47  ? 248 VAL B O   1 
ATOM   3011 C  CB  . VAL B 2 78  ? -21.993 12.912  12.468  1   31.18  ? 248 VAL B CB  1 
ATOM   3012 C  CG1 . VAL B 2 78  ? -20.642 13.459  12.047  1   33.01  ? 248 VAL B CG1 1 
ATOM   3013 C  CG2 . VAL B 2 78  ? -21.841 11.53   13.084  1   31.7   ? 248 VAL B CG2 1 
ATOM   3014 N  N   . LEU B 2 79  ? -21.905 16.177  13.424  1   28.23  ? 249 LEU B N   1 
ATOM   3015 C  CA  . LEU B 2 79  ? -21.776 17.525  12.9    1   28.33  ? 249 LEU B CA  1 
ATOM   3016 C  C   . LEU B 2 79  ? -21.001 17.476  11.579  1   29.9   ? 249 LEU B C   1 
ATOM   3017 O  O   . LEU B 2 79  ? -20.133 16.622  11.389  1   27.6   ? 249 LEU B O   1 
ATOM   3018 C  CB  . LEU B 2 79  ? -21.057 18.44   13.906  1   28.43  ? 249 LEU B CB  1 
ATOM   3019 C  CG  . LEU B 2 79  ? -21.751 18.718  15.241  1   31.54  ? 249 LEU B CG  1 
ATOM   3020 C  CD1 . LEU B 2 79  ? -21.067 19.849  15.978  1   29.62  ? 249 LEU B CD1 1 
ATOM   3021 C  CD2 . LEU B 2 79  ? -23.234 19.046  15.05   1   32.84  ? 249 LEU B CD2 1 
ATOM   3022 N  N   . ARG B 2 80  ? -21.299 18.417  10.674  1   30.9   ? 250 ARG B N   1 
ATOM   3023 C  CA  . ARG B 2 80  ? -20.696 18.408  9.348   1   31.19  ? 250 ARG B CA  1 
ATOM   3024 C  C   . ARG B 2 80  ? -19.168 18.365  9.416   1   30.76  ? 250 ARG B C   1 
ATOM   3025 O  O   . ARG B 2 80  ? -18.533 17.669  8.617   1   26.15  ? 250 ARG B O   1 
ATOM   3026 C  CB  . ARG B 2 80  ? -21.168 19.6    8.537   1   31.25  ? 250 ARG B CB  1 
ATOM   3027 C  CG  . ARG B 2 80  ? -20.604 20.938  9.005   1   34.49  ? 250 ARG B CG  1 
ATOM   3028 C  CD  . ARG B 2 80  ? -21.305 22.093  8.337   1   33.97  ? 250 ARG B CD  1 
ATOM   3029 N  NE  . ARG B 2 80  ? -22.728 22.113  8.658   1   35.84  ? 250 ARG B NE  1 
ATOM   3030 C  CZ  . ARG B 2 80  ? -23.608 22.967  8.144   1   37.26  ? 250 ARG B CZ  1 
ATOM   3031 N  NH1 . ARG B 2 80  ? -23.312 23.73   7.103   1   37.46  ? 250 ARG B NH1 1 
ATOM   3032 N  NH2 . ARG B 2 80  ? -24.823 23.047  8.679   1   35.59  ? 250 ARG B NH2 1 
ATOM   3033 N  N   . GLY B 2 81  ? -18.596 19.079  10.399  1   29.9   ? 251 GLY B N   1 
ATOM   3034 C  CA  . GLY B 2 81  ? -17.159 19.095  10.633  1   29.38  ? 251 GLY B CA  1 
ATOM   3035 C  C   . GLY B 2 81  ? -16.529 17.734  10.935  1   30.3   ? 251 GLY B C   1 
ATOM   3036 O  O   . GLY B 2 81  ? -15.325 17.557  10.759  1   30.67  ? 251 GLY B O   1 
ATOM   3037 N  N   . LYS B 2 82  ? -17.347 16.778  11.399  1   29.93  ? 252 LYS B N   1 
ATOM   3038 C  CA  . LYS B 2 82  ? -16.858 15.463  11.775  1   27.64  ? 252 LYS B CA  1 
ATOM   3039 C  C   . LYS B 2 82  ? -17.248 14.358  10.805  1   26.1   ? 252 LYS B C   1 
ATOM   3040 O  O   . LYS B 2 82  ? -16.871 13.202  10.993  1   26.43  ? 252 LYS B O   1 
ATOM   3041 C  CB  . LYS B 2 82  ? -17.372 15.123  13.181  1   28.07  ? 252 LYS B CB  1 
ATOM   3042 C  CG  . LYS B 2 82  ? -16.74  15.984  14.278  1   29.64  ? 252 LYS B CG  1 
ATOM   3043 C  CD  . LYS B 2 82  ? -15.238 15.727  14.37   1   33.44  ? 252 LYS B CD  1 
ATOM   3044 C  CE  . LYS B 2 82  ? -14.632 16.169  15.665  1   34.1   ? 252 LYS B CE  1 
ATOM   3045 N  NZ  . LYS B 2 82  ? -14.688 17.638  15.777  1   37.41  ? 252 LYS B NZ  1 
ATOM   3046 N  N   . LEU B 2 83  ? -18.01  14.707  9.768   1   26.96  ? 253 LEU B N   1 
ATOM   3047 C  CA  . LEU B 2 83  ? -18.465 13.712  8.81    1   28.75  ? 253 LEU B CA  1 
ATOM   3048 C  C   . LEU B 2 83  ? -17.292 13.017  8.123   1   30.16  ? 253 LEU B C   1 
ATOM   3049 O  O   . LEU B 2 83  ? -17.316 11.807  7.919   1   31.05  ? 253 LEU B O   1 
ATOM   3050 C  CB  . LEU B 2 83  ? -19.389 14.346  7.77    1   28.08  ? 253 LEU B CB  1 
ATOM   3051 C  CG  . LEU B 2 83  ? -19.936 13.419  6.712   1   28.69  ? 253 LEU B CG  1 
ATOM   3052 C  CD1 . LEU B 2 83  ? -20.723 12.251  7.32    1   27.78  ? 253 LEU B CD1 1 
ATOM   3053 C  CD2 . LEU B 2 83  ? -20.842 14.181  5.751   1   29.11  ? 253 LEU B CD2 1 
ATOM   3054 N  N   . GLN B 2 84  ? -16.26  13.786  7.774   1   31.27  ? 254 GLN B N   1 
ATOM   3055 C  CA  . GLN B 2 84  ? -15.096 13.215  7.114   1   34.43  ? 254 GLN B CA  1 
ATOM   3056 C  C   . GLN B 2 84  ? -14.299 12.292  8.041   1   31.47  ? 254 GLN B C   1 
ATOM   3057 O  O   . GLN B 2 84  ? -13.657 11.355  7.573   1   30.24  ? 254 GLN B O   1 
ATOM   3058 C  CB  . GLN B 2 84  ? -14.189 14.324  6.54    1   33.89  ? 254 GLN B CB  1 
ATOM   3059 C  CG  . GLN B 2 84  ? -13.155 13.792  5.553   1   34.44  ? 254 GLN B CG  1 
ATOM   3060 C  CD  . GLN B 2 84  ? -12.231 14.856  5.038   1   34.69  ? 254 GLN B CD  1 
ATOM   3061 O  OE1 . GLN B 2 84  ? -12.052 15.898  5.655   1   39     ? 254 GLN B OE1 1 
ATOM   3062 N  NE2 . GLN B 2 84  ? -11.594 14.598  3.913   1   33.21  ? 254 GLN B NE2 1 
ATOM   3063 N  N   . LEU B 2 85  ? -14.347 12.56   9.349   1   28.93  ? 255 LEU B N   1 
ATOM   3064 C  CA  . LEU B 2 85  ? -13.657 11.725  10.316  1   29.85  ? 255 LEU B CA  1 
ATOM   3065 C  C   . LEU B 2 85  ? -14.291 10.337  10.365  1   27.9   ? 255 LEU B C   1 
ATOM   3066 O  O   . LEU B 2 85  ? -13.577 9.338   10.409  1   27.3   ? 255 LEU B O   1 
ATOM   3067 C  CB  . LEU B 2 85  ? -13.653 12.372  11.706  1   28.39  ? 255 LEU B CB  1 
ATOM   3068 C  CG  . LEU B 2 85  ? -12.971 11.558  12.8    1   30.67  ? 255 LEU B CG  1 
ATOM   3069 C  CD1 . LEU B 2 85  ? -11.509 11.249  12.448  1   30.3   ? 255 LEU B CD1 1 
ATOM   3070 C  CD2 . LEU B 2 85  ? -13.053 12.28   14.117  1   30.71  ? 255 LEU B CD2 1 
ATOM   3071 N  N   . VAL B 2 86  ? -15.63  10.295  10.351  1   26.76  ? 256 VAL B N   1 
ATOM   3072 C  CA  . VAL B 2 86  ? -16.367 9.045   10.286  1   27.5   ? 256 VAL B CA  1 
ATOM   3073 C  C   . VAL B 2 86  ? -15.971 8.272   9.031   1   27.81  ? 256 VAL B C   1 
ATOM   3074 O  O   . VAL B 2 86  ? -15.602 7.102   9.107   1   26.37  ? 256 VAL B O   1 
ATOM   3075 C  CB  . VAL B 2 86  ? -17.882 9.304   10.327  1   28.61  ? 256 VAL B CB  1 
ATOM   3076 C  CG1 . VAL B 2 86  ? -18.673 8.036   10.027  1   28.32  ? 256 VAL B CG1 1 
ATOM   3077 C  CG2 . VAL B 2 86  ? -18.293 9.915   11.657  1   27.73  ? 256 VAL B CG2 1 
ATOM   3078 N  N   . GLY B 2 87  ? -16.019 8.96    7.887   1   28.94  ? 257 GLY B N   1 
ATOM   3079 C  CA  . GLY B 2 87  ? -15.67  8.368   6.607   1   30.23  ? 257 GLY B CA  1 
ATOM   3080 C  C   . GLY B 2 87  ? -14.236 7.85    6.536   1   31.19  ? 257 GLY B C   1 
ATOM   3081 O  O   . GLY B 2 87  ? -13.997 6.789   5.974   1   30.75  ? 257 GLY B O   1 
ATOM   3082 N  N   . THR B 2 88  ? -13.281 8.606   7.095   1   32.25  ? 258 THR B N   1 
ATOM   3083 C  CA  . THR B 2 88  ? -11.891 8.175   7.104   1   33.51  ? 258 THR B CA  1 
ATOM   3084 C  C   . THR B 2 88  ? -11.727 6.898   7.924   1   31.99  ? 258 THR B C   1 
ATOM   3085 O  O   . THR B 2 88  ? -11.037 5.977   7.499   1   29.39  ? 258 THR B O   1 
ATOM   3086 C  CB  . THR B 2 88  ? -10.971 9.278   7.607   1   33.72  ? 258 THR B CB  1 
ATOM   3087 O  OG1 . THR B 2 88  ? -11.238 10.465  6.877   1   35.52  ? 258 THR B OG1 1 
ATOM   3088 C  CG2 . THR B 2 88  ? -9.511  8.94    7.437   1   36.21  ? 258 THR B CG2 1 
ATOM   3089 N  N   . ALA B 2 89  ? -12.381 6.845   9.088   1   33.15  ? 259 ALA B N   1 
ATOM   3090 C  CA  . ALA B 2 89  ? -12.288 5.686   9.964   1   33.58  ? 259 ALA B CA  1 
ATOM   3091 C  C   . ALA B 2 89  ? -12.96  4.47    9.333   1   32.27  ? 259 ALA B C   1 
ATOM   3092 O  O   . ALA B 2 89  ? -12.472 3.347   9.461   1   30.08  ? 259 ALA B O   1 
ATOM   3093 C  CB  . ALA B 2 89  ? -12.911 5.984   11.316  1   34.61  ? 259 ALA B CB  1 
ATOM   3094 N  N   . ALA B 2 90  ? -14.081 4.711   8.641   1   34.07  ? 260 ALA B N   1 
ATOM   3095 C  CA  . ALA B 2 90  ? -14.779 3.652   7.933   1   31.37  ? 260 ALA B CA  1 
ATOM   3096 C  C   . ALA B 2 90  ? -13.898 3.041   6.841   1   32.08  ? 260 ALA B C   1 
ATOM   3097 O  O   . ALA B 2 90  ? -13.826 1.818   6.7     1   31.92  ? 260 ALA B O   1 
ATOM   3098 C  CB  . ALA B 2 90  ? -16.073 4.175   7.348   1   32.91  ? 260 ALA B CB  1 
ATOM   3099 N  N   . MET B 2 91  ? -13.209 3.907   6.089   1   32.08  ? 261 MET B N   1 
ATOM   3100 C  CA  . MET B 2 91  ? -12.361 3.464   4.998   1   31.39  ? 261 MET B CA  1 
ATOM   3101 C  C   . MET B 2 91  ? -11.162 2.683   5.54    1   30.84  ? 261 MET B C   1 
ATOM   3102 O  O   . MET B 2 91  ? -10.727 1.712   4.926   1   33.24  ? 261 MET B O   1 
ATOM   3103 C  CB  . MET B 2 91  ? -11.908 4.675   4.153   1   34.45  ? 261 MET B CB  1 
ATOM   3104 C  CG  . MET B 2 91  ? -11.329 4.281   2.812   1   37.84  ? 261 MET B CG  1 
ATOM   3105 S  SD  . MET B 2 91  ? -12.558 3.483   1.759   1   36.18  ? 261 MET B SD  1 
ATOM   3106 C  CE  . MET B 2 91  ? -12.214 4.263   0.217   1   39.62  ? 261 MET B CE  1 
ATOM   3107 N  N   . LEU B 2 92  ? -10.653 3.094   6.706   1   27.72  ? 262 LEU B N   1 
ATOM   3108 C  CA  . LEU B 2 92  ? -9.565  2.396   7.369   1   28.56  ? 262 LEU B CA  1 
ATOM   3109 C  C   . LEU B 2 92  ? -9.988  0.981   7.771   1   30.4   ? 262 LEU B C   1 
ATOM   3110 O  O   . LEU B 2 92  ? -9.257  0.015   7.533   1   29.89  ? 262 LEU B O   1 
ATOM   3111 C  CB  . LEU B 2 92  ? -9.116  3.202   8.604   1   26.59  ? 262 LEU B CB  1 
ATOM   3112 C  CG  . LEU B 2 92  ? -8.095  2.561   9.534   1   25.68  ? 262 LEU B CG  1 
ATOM   3113 C  CD1 . LEU B 2 92  ? -6.76   2.338   8.838   1   25.87  ? 262 LEU B CD1 1 
ATOM   3114 C  CD2 . LEU B 2 92  ? -7.878  3.404   10.758  1   24.76  ? 262 LEU B CD2 1 
ATOM   3115 N  N   . LEU B 2 93  ? -11.183 0.874   8.364   1   26.17  ? 263 LEU B N   1 
ATOM   3116 C  CA  . LEU B 2 93  ? -11.697 -0.406  8.812   1   26.26  ? 263 LEU B CA  1 
ATOM   3117 C  C   . LEU B 2 93  ? -11.96  -1.333  7.625   1   26.33  ? 263 LEU B C   1 
ATOM   3118 O  O   . LEU B 2 93  ? -11.619 -2.511  7.675   1   26.34  ? 263 LEU B O   1 
ATOM   3119 C  CB  . LEU B 2 93  ? -12.971 -0.191  9.626   1   27.85  ? 263 LEU B CB  1 
ATOM   3120 C  CG  . LEU B 2 93  ? -12.751 0.293   11.068  1   28.26  ? 263 LEU B CG  1 
ATOM   3121 C  CD1 . LEU B 2 93  ? -14.075 0.755   11.697  1   27.32  ? 263 LEU B CD1 1 
ATOM   3122 C  CD2 . LEU B 2 93  ? -12.123 -0.795  11.909  1   27.82  ? 263 LEU B CD2 1 
ATOM   3123 N  N   . ALA B 2 94  ? -12.553 -0.787  6.557   1   27.21  ? 264 ALA B N   1 
ATOM   3124 C  CA  . ALA B 2 94  ? -12.819 -1.548  5.345   1   27.5   ? 264 ALA B CA  1 
ATOM   3125 C  C   . ALA B 2 94  ? -11.522 -2.052  4.723   1   27.17  ? 264 ALA B C   1 
ATOM   3126 O  O   . ALA B 2 94  ? -11.455 -3.179  4.257   1   28.25  ? 264 ALA B O   1 
ATOM   3127 C  CB  . ALA B 2 94  ? -13.578 -0.702  4.338   1   29.12  ? 264 ALA B CB  1 
ATOM   3128 N  N   . SER B 2 95  ? -10.5   -1.197  4.722   1   29.54  ? 265 SER B N   1 
ATOM   3129 C  CA  . SER B 2 95  ? -9.174  -1.564  4.254   1   28.77  ? 265 SER B CA  1 
ATOM   3130 C  C   . SER B 2 95  ? -8.581  -2.694  5.088   1   27.02  ? 265 SER B C   1 
ATOM   3131 O  O   . SER B 2 95  ? -8.077  -3.665  4.538   1   26.85  ? 265 SER B O   1 
ATOM   3132 C  CB  . SER B 2 95  ? -8.24   -0.35   4.267   1   29.49  ? 265 SER B CB  1 
ATOM   3133 O  OG  . SER B 2 95  ? -8.712  0.659   3.387   1   33.13  ? 265 SER B OG  1 
ATOM   3134 N  N   . LYS B 2 96  ? -8.631  -2.579  6.419   1   26.19  ? 266 LYS B N   1 
ATOM   3135 C  CA  . LYS B 2 96  ? -8.088  -3.643  7.249   1   27.31  ? 266 LYS B CA  1 
ATOM   3136 C  C   . LYS B 2 96  ? -8.837  -4.957  7.025   1   27.63  ? 266 LYS B C   1 
ATOM   3137 O  O   . LYS B 2 96  ? -8.242  -6.027  7.079   1   27.18  ? 266 LYS B O   1 
ATOM   3138 C  CB  . LYS B 2 96  ? -8.135  -3.268  8.716   1   30.27  ? 266 LYS B CB  1 
ATOM   3139 C  CG  . LYS B 2 96  ? -7.137  -2.204  9.129   1   30.39  ? 266 LYS B CG  1 
ATOM   3140 C  CD  . LYS B 2 96  ? -7.34   -1.816  10.577  1   29.91  ? 266 LYS B CD  1 
ATOM   3141 C  CE  . LYS B 2 96  ? -6.347  -0.817  11.032  1   29.67  ? 266 LYS B CE  1 
ATOM   3142 N  NZ  . LYS B 2 96  ? -6.472  -0.56   12.475  1   29.12  ? 266 LYS B NZ  1 
ATOM   3143 N  N   . PHE B 2 97  ? -10.151 -4.876  6.779   1   28.58  ? 267 PHE B N   1 
ATOM   3144 C  CA  . PHE B 2 97  ? -10.954 -6.062  6.545   1   28.17  ? 267 PHE B CA  1 
ATOM   3145 C  C   . PHE B 2 97  ? -10.632 -6.71   5.203   1   28.56  ? 267 PHE B C   1 
ATOM   3146 O  O   . PHE B 2 97  ? -10.378 -7.908  5.129   1   29.28  ? 267 PHE B O   1 
ATOM   3147 C  CB  . PHE B 2 97  ? -12.436 -5.726  6.578   1   29.83  ? 267 PHE B CB  1 
ATOM   3148 C  CG  . PHE B 2 97  ? -13.334 -6.939  6.454   1   29.39  ? 267 PHE B CG  1 
ATOM   3149 C  CD1 . PHE B 2 97  ? -13.634 -7.719  7.559   1   29.73  ? 267 PHE B CD1 1 
ATOM   3150 C  CD2 . PHE B 2 97  ? -13.892 -7.282  5.236   1   29.47  ? 267 PHE B CD2 1 
ATOM   3151 C  CE1 . PHE B 2 97  ? -14.452 -8.836  7.437   1   31     ? 267 PHE B CE1 1 
ATOM   3152 C  CE2 . PHE B 2 97  ? -14.711 -8.4    5.118   1   29.12  ? 267 PHE B CE2 1 
ATOM   3153 C  CZ  . PHE B 2 97  ? -14.99  -9.165  6.217   1   31.15  ? 267 PHE B CZ  1 
ATOM   3154 N  N   . GLU B 2 98  ? -10.643 -5.896  4.148   1   27.93  ? 268 GLU B N   1 
ATOM   3155 C  CA  . GLU B 2 98  ? -10.704 -6.4    2.786   1   27.54  ? 268 GLU B CA  1 
ATOM   3156 C  C   . GLU B 2 98  ? -9.377  -6.416  2.025   1   25.44  ? 268 GLU B C   1 
ATOM   3157 O  O   . GLU B 2 98  ? -9.212  -7.245  1.138   1   22.93  ? 268 GLU B O   1 
ATOM   3158 C  CB  . GLU B 2 98  ? -11.716 -5.568  1.992   1   29.04  ? 268 GLU B CB  1 
ATOM   3159 C  CG  . GLU B 2 98  ? -12.125 -6.208  0.672   1   31.81  ? 268 GLU B CG  1 
ATOM   3160 C  CD  . GLU B 2 98  ? -12.78  -7.582  0.796   1   33.05  ? 268 GLU B CD  1 
ATOM   3161 O  OE1 . GLU B 2 98  ? -13.414 -7.852  1.846   1   32.58  ? 268 GLU B OE1 1 
ATOM   3162 O  OE2 . GLU B 2 98  ? -12.661 -8.387  -0.157  1   29.75  ? 268 GLU B OE2 1 
ATOM   3163 N  N   . GLU B 2 99  ? -8.44   -5.518  2.365   1   23.95  ? 269 GLU B N   1 
ATOM   3164 C  CA  . GLU B 2 99  ? -7.211  -5.383  1.603   1   26.06  ? 269 GLU B CA  1 
ATOM   3165 C  C   . GLU B 2 99  ? -6.091  -6.31   2.08    1   30.16  ? 269 GLU B C   1 
ATOM   3166 O  O   . GLU B 2 99  ? -5.934  -6.547  3.277   1   28.65  ? 269 GLU B O   1 
ATOM   3167 C  CB  . GLU B 2 99  ? -6.687  -3.94   1.638   1   26.79  ? 269 GLU B CB  1 
ATOM   3168 C  CG  . GLU B 2 99  ? -7.562  -2.892  0.969   1   29.08  ? 269 GLU B CG  1 
ATOM   3169 C  CD  . GLU B 2 99  ? -7.707  -2.974  -0.547  1   29.14  ? 269 GLU B CD  1 
ATOM   3170 O  OE1 . GLU B 2 99  ? -6.702  -3.278  -1.229  1   34.22  ? 269 GLU B OE1 1 
ATOM   3171 O  OE2 . GLU B 2 99  ? -8.824  -2.702  -1.049  1   27.98  ? 269 GLU B OE2 1 
ATOM   3172 N  N   . ILE B 2 100 ? -5.295  -6.791  1.119   1   29.52  ? 270 ILE B N   1 
ATOM   3173 C  CA  . ILE B 2 100 ? -4.059  -7.503  1.398   1   29.78  ? 270 ILE B CA  1 
ATOM   3174 C  C   . ILE B 2 100 ? -3.052  -6.571  2.059   1   32.01  ? 270 ILE B C   1 
ATOM   3175 O  O   . ILE B 2 100 ? -2.444  -6.932  3.061   1   34.8   ? 270 ILE B O   1 
ATOM   3176 C  CB  . ILE B 2 100 ? -3.464  -8.094  0.087   1   30.04  ? 270 ILE B CB  1 
ATOM   3177 C  CG1 . ILE B 2 100 ? -4.449  -9.047  -0.622  1   29.17  ? 270 ILE B CG1 1 
ATOM   3178 C  CG2 . ILE B 2 100 ? -2.117  -8.793  0.341   1   30.82  ? 270 ILE B CG2 1 
ATOM   3179 C  CD1 . ILE B 2 100 ? -3.996  -9.508  -1.97   1   30.05  ? 270 ILE B CD1 1 
ATOM   3180 N  N   . TYR B 2 101 ? -2.87   -5.384  1.467   1   34.13  ? 271 TYR B N   1 
ATOM   3181 C  CA  . TYR B 2 101 ? -1.921  -4.399  1.961   1   35.18  ? 271 TYR B CA  1 
ATOM   3182 C  C   . TYR B 2 101 ? -2.644  -3.093  2.25    1   34.05  ? 271 TYR B C   1 
ATOM   3183 O  O   . TYR B 2 101 ? -2.582  -2.173  1.443   1   36.75  ? 271 TYR B O   1 
ATOM   3184 C  CB  . TYR B 2 101 ? -0.782  -4.138  0.939   1   36.74  ? 271 TYR B CB  1 
ATOM   3185 C  CG  . TYR B 2 101 ? 0.085   -5.341  0.672   1   35.77  ? 271 TYR B CG  1 
ATOM   3186 C  CD1 . TYR B 2 101 ? 0.959   -5.824  1.641   1   35.85  ? 271 TYR B CD1 1 
ATOM   3187 C  CD2 . TYR B 2 101 ? 0.02    -6.015  -0.543  1   39.51  ? 271 TYR B CD2 1 
ATOM   3188 C  CE1 . TYR B 2 101 ? 1.758   -6.94   1.403   1   36.8   ? 271 TYR B CE1 1 
ATOM   3189 C  CE2 . TYR B 2 101 ? 0.818   -7.131  -0.796  1   41.3   ? 271 TYR B CE2 1 
ATOM   3190 C  CZ  . TYR B 2 101 ? 1.678   -7.596  0.186   1   40.84  ? 271 TYR B CZ  1 
ATOM   3191 O  OH  . TYR B 2 101 ? 2.46    -8.696  -0.055  1   49.37  ? 271 TYR B OH  1 
ATOM   3192 N  N   . PRO B 2 102 ? -3.34   -2.957  3.405   1   36.9   ? 272 PRO B N   1 
ATOM   3193 C  CA  . PRO B 2 102 ? -4.07   -1.725  3.709   1   33.79  ? 272 PRO B CA  1 
ATOM   3194 C  C   . PRO B 2 102 ? -3.109  -0.556  3.847   1   31.61  ? 272 PRO B C   1 
ATOM   3195 O  O   . PRO B 2 102 ? -1.966  -0.749  4.249   1   36.7   ? 272 PRO B O   1 
ATOM   3196 C  CB  . PRO B 2 102 ? -4.758  -2.026  5.032   1   34.97  ? 272 PRO B CB  1 
ATOM   3197 C  CG  . PRO B 2 102 ? -3.97   -3.163  5.632   1   34.43  ? 272 PRO B CG  1 
ATOM   3198 C  CD  . PRO B 2 102 ? -3.421  -3.952  4.487   1   34.53  ? 272 PRO B CD  1 
ATOM   3199 N  N   . PRO B 2 103 ? -3.508  0.688   3.505   1   32.85  ? 273 PRO B N   1 
ATOM   3200 C  CA  . PRO B 2 103 ? -2.65   1.836   3.792   1   32.93  ? 273 PRO B CA  1 
ATOM   3201 C  C   . PRO B 2 103 ? -2.532  2       5.305   1   32.59  ? 273 PRO B C   1 
ATOM   3202 O  O   . PRO B 2 103 ? -3.425  1.609   6.056   1   28.07  ? 273 PRO B O   1 
ATOM   3203 C  CB  . PRO B 2 103 ? -3.347  3.009   3.086   1   31.96  ? 273 PRO B CB  1 
ATOM   3204 C  CG  . PRO B 2 103 ? -4.395  2.37    2.175   1   31.15  ? 273 PRO B CG  1 
ATOM   3205 C  CD  . PRO B 2 103 ? -4.747  1.057   2.806   1   32.08  ? 273 PRO B CD  1 
ATOM   3206 N  N   . GLU B 2 104 ? -1.399  2.559   5.734   1   36.32  ? 274 GLU B N   1 
ATOM   3207 C  CA  . GLU B 2 104 ? -1.157  2.846   7.135   1   38.25  ? 274 GLU B CA  1 
ATOM   3208 C  C   . GLU B 2 104 ? -2.091  3.956   7.604   1   35.16  ? 274 GLU B C   1 
ATOM   3209 O  O   . GLU B 2 104 ? -2.586  4.748   6.801   1   31.18  ? 274 GLU B O   1 
ATOM   3210 C  CB  . GLU B 2 104 ? 0.279   3.308   7.347   1   45.37  ? 274 GLU B CB  1 
ATOM   3211 C  CG  . GLU B 2 104 ? 1.347   2.326   6.954   1   51.75  ? 274 GLU B CG  1 
ATOM   3212 C  CD  . GLU B 2 104 ? 2.72    2.898   7.231   1   62.73  ? 274 GLU B CD  1 
ATOM   3213 O  OE1 . GLU B 2 104 ? 2.963   4.068   6.847   1   63.17  ? 274 GLU B OE1 1 
ATOM   3214 O  OE2 . GLU B 2 104 ? 3.548   2.182   7.841   1   79.28  ? 274 GLU B OE2 1 
ATOM   3215 N  N   . VAL B 2 105 ? -2.302  4.012   8.916   1   32.39  ? 275 VAL B N   1 
ATOM   3216 C  CA  . VAL B 2 105 ? -3.084  5.074   9.52    1   33.6   ? 275 VAL B CA  1 
ATOM   3217 C  C   . VAL B 2 105 ? -2.566  6.439   9.075   1   33.24  ? 275 VAL B C   1 
ATOM   3218 O  O   . VAL B 2 105 ? -3.363  7.313   8.746   1   34.33  ? 275 VAL B O   1 
ATOM   3219 C  CB  . VAL B 2 105 ? -3.096  4.943   11.065  1   36.11  ? 275 VAL B CB  1 
ATOM   3220 C  CG1 . VAL B 2 105 ? -3.843  6.101   11.703  1   37.75  ? 275 VAL B CG1 1 
ATOM   3221 C  CG2 . VAL B 2 105 ? -3.696  3.609   11.494  1   37.71  ? 275 VAL B CG2 1 
ATOM   3222 N  N   . ALA B 2 106 ? -1.236  6.616   9.05    1   31.41  ? 276 ALA B N   1 
ATOM   3223 C  CA  . ALA B 2 106 ? -0.647  7.895   8.69    1   32.9   ? 276 ALA B CA  1 
ATOM   3224 C  C   . ALA B 2 106 ? -1.128  8.392   7.327   1   34.67  ? 276 ALA B C   1 
ATOM   3225 O  O   . ALA B 2 106 ? -1.342  9.587   7.147   1   41.03  ? 276 ALA B O   1 
ATOM   3226 C  CB  . ALA B 2 106 ? 0.864   7.815   8.714   1   32.76  ? 276 ALA B CB  1 
ATOM   3227 N  N   . GLU B 2 107 ? -1.3    7.467   6.381   1   33.92  ? 277 GLU B N   1 
ATOM   3228 C  CA  . GLU B 2 107 ? -1.764  7.804   5.046   1   36.34  ? 277 GLU B CA  1 
ATOM   3229 C  C   . GLU B 2 107 ? -3.214  8.282   5.075   1   36.04  ? 277 GLU B C   1 
ATOM   3230 O  O   . GLU B 2 107 ? -3.576  9.195   4.344   1   36.55  ? 277 GLU B O   1 
ATOM   3231 C  CB  . GLU B 2 107 ? -1.582  6.596   4.106   1   38.28  ? 277 GLU B CB  1 
ATOM   3232 C  CG  . GLU B 2 107 ? -0.122  6.303   3.799   1   41.67  ? 277 GLU B CG  1 
ATOM   3233 C  CD  . GLU B 2 107 ? 0.133   5.016   3.037   1   51.56  ? 277 GLU B CD  1 
ATOM   3234 O  OE1 . GLU B 2 107 ? -0.082  3.923   3.608   1   58.32  ? 277 GLU B OE1 1 
ATOM   3235 O  OE2 . GLU B 2 107 ? 0.555   5.103   1.861   1   59.62  ? 277 GLU B OE2 1 
ATOM   3236 N  N   . PHE B 2 108 ? -4.038  7.662   5.927   1   37.54  ? 278 PHE B N   1 
ATOM   3237 C  CA  . PHE B 2 108 ? -5.417  8.088   6.123   1   36.94  ? 278 PHE B CA  1 
ATOM   3238 C  C   . PHE B 2 108 ? -5.511  9.454   6.809   1   39.47  ? 278 PHE B C   1 
ATOM   3239 O  O   . PHE B 2 108 ? -6.491  10.166  6.618   1   42.84  ? 278 PHE B O   1 
ATOM   3240 C  CB  . PHE B 2 108 ? -6.206  7.033   6.923   1   35.23  ? 278 PHE B CB  1 
ATOM   3241 C  CG  . PHE B 2 108 ? -6.619  5.846   6.099   1   34.29  ? 278 PHE B CG  1 
ATOM   3242 C  CD1 . PHE B 2 108 ? -7.69   5.924   5.229   1   33.65  ? 278 PHE B CD1 1 
ATOM   3243 C  CD2 . PHE B 2 108 ? -5.919  4.662   6.169   1   33.37  ? 278 PHE B CD2 1 
ATOM   3244 C  CE1 . PHE B 2 108 ? -8.067  4.819   4.467   1   33.96  ? 278 PHE B CE1 1 
ATOM   3245 C  CE2 . PHE B 2 108 ? -6.283  3.57    5.39    1   31.13  ? 278 PHE B CE2 1 
ATOM   3246 C  CZ  . PHE B 2 108 ? -7.348  3.653   4.544   1   32.95  ? 278 PHE B CZ  1 
ATOM   3247 N  N   . VAL B 2 109 ? -4.506  9.803   7.625   1   36.75  ? 279 VAL B N   1 
ATOM   3248 C  CA  . VAL B 2 109 ? -4.428  11.129  8.21    1   36.37  ? 279 VAL B CA  1 
ATOM   3249 C  C   . VAL B 2 109 ? -4.016  12.132  7.141   1   39.23  ? 279 VAL B C   1 
ATOM   3250 O  O   . VAL B 2 109 ? -4.533  13.242  7.117   1   41.99  ? 279 VAL B O   1 
ATOM   3251 C  CB  . VAL B 2 109 ? -3.466  11.197  9.411   1   37.17  ? 279 VAL B CB  1 
ATOM   3252 C  CG1 . VAL B 2 109 ? -3.213  12.64   9.847   1   36.55  ? 279 VAL B CG1 1 
ATOM   3253 C  CG2 . VAL B 2 109 ? -3.974  10.359  10.577  1   35.72  ? 279 VAL B CG2 1 
ATOM   3254 N  N   . TYR B 2 110 ? -3.067  11.737  6.287   1   38.52  ? 280 TYR B N   1 
ATOM   3255 C  CA  . TYR B 2 110 ? -2.57   12.583  5.213   1   40.3   ? 280 TYR B CA  1 
ATOM   3256 C  C   . TYR B 2 110 ? -3.677  13.002  4.242   1   38.18  ? 280 TYR B C   1 
ATOM   3257 O  O   . TYR B 2 110 ? -3.781  14.172  3.898   1   36.51  ? 280 TYR B O   1 
ATOM   3258 C  CB  . TYR B 2 110 ? -1.416  11.876  4.463   1   43.76  ? 280 TYR B CB  1 
ATOM   3259 C  CG  . TYR B 2 110 ? -0.852  12.665  3.293   1   50.04  ? 280 TYR B CG  1 
ATOM   3260 C  CD1 . TYR B 2 110 ? 0       13.747  3.499   1   51.91  ? 280 TYR B CD1 1 
ATOM   3261 C  CD2 . TYR B 2 110 ? -1.192  12.346  1.982   1   51.28  ? 280 TYR B CD2 1 
ATOM   3262 C  CE1 . TYR B 2 110 ? 0.509   14.481  2.431   1   52.05  ? 280 TYR B CE1 1 
ATOM   3263 C  CE2 . TYR B 2 110 ? -0.686  13.069  0.906   1   51.82  ? 280 TYR B CE2 1 
ATOM   3264 C  CZ  . TYR B 2 110 ? 0.166   14.137  1.134   1   53.2   ? 280 TYR B CZ  1 
ATOM   3265 O  OH  . TYR B 2 110 ? 0.665   14.857  0.071   1   48.6   ? 280 TYR B OH  1 
ATOM   3266 N  N   . ILE B 2 111 ? -4.529  12.065  3.813   1   39.64  ? 281 ILE B N   1 
ATOM   3267 C  CA  . ILE B 2 111 ? -5.565  12.402  2.844   1   42.26  ? 281 ILE B CA  1 
ATOM   3268 C  C   . ILE B 2 111 ? -6.671  13.325  3.356   1   39.57  ? 281 ILE B C   1 
ATOM   3269 O  O   . ILE B 2 111 ? -7.424  13.858  2.548   1   37.71  ? 281 ILE B O   1 
ATOM   3270 C  CB  . ILE B 2 111 ? -6.242  11.171  2.228   1   46.23  ? 281 ILE B CB  1 
ATOM   3271 C  CG1 . ILE B 2 111 ? -6.579  10.141  3.311   1   47.49  ? 281 ILE B CG1 1 
ATOM   3272 C  CG2 . ILE B 2 111 ? -5.395  10.601  1.106   1   45.95  ? 281 ILE B CG2 1 
ATOM   3273 C  CD1 . ILE B 2 111 ? -7.865  9.476   3.132   1   51.85  ? 281 ILE B CD1 1 
ATOM   3274 N  N   . THR B 2 112 ? -6.791  13.497  4.679   1   41.65  ? 282 THR B N   1 
ATOM   3275 C  CA  . THR B 2 112 ? -7.724  14.474  5.224   1   45.25  ? 282 THR B CA  1 
ATOM   3276 C  C   . THR B 2 112 ? -7.122  15.873  5.329   1   51.13  ? 282 THR B C   1 
ATOM   3277 O  O   . THR B 2 112 ? -7.691  16.721  6.007   1   55.13  ? 282 THR B O   1 
ATOM   3278 C  CB  . THR B 2 112 ? -8.249  14.053  6.6     1   45.05  ? 282 THR B CB  1 
ATOM   3279 O  OG1 . THR B 2 112 ? -7.191  14.147  7.552   1   45.52  ? 282 THR B OG1 1 
ATOM   3280 C  CG2 . THR B 2 112 ? -8.874  12.648  6.589   1   41.26  ? 282 THR B CG2 1 
ATOM   3281 N  N   . ASP B 2 113 ? -5.977  16.098  4.659   1   62.92  ? 283 ASP B N   1 
ATOM   3282 C  CA  . ASP B 2 113 ? -5.229  17.349  4.697   1   64.56  ? 283 ASP B CA  1 
ATOM   3283 C  C   . ASP B 2 113 ? -4.957  17.848  6.113   1   60.22  ? 283 ASP B C   1 
ATOM   3284 O  O   . ASP B 2 113 ? -4.996  19.047  6.382   1   60.47  ? 283 ASP B O   1 
ATOM   3285 C  CB  . ASP B 2 113 ? -5.947  18.43   3.876   1   69.84  ? 283 ASP B CB  1 
ATOM   3286 C  CG  . ASP B 2 113 ? -6.067  18.097  2.403   1   73.59  ? 283 ASP B CG  1 
ATOM   3287 O  OD1 . ASP B 2 113 ? -5.085  17.58   1.825   1   71.55  ? 283 ASP B OD1 1 
ATOM   3288 O  OD2 . ASP B 2 113 ? -7.135  18.366  1.821   1   77.54  ? 283 ASP B OD2 1 
ATOM   3289 N  N   . ASP B 2 114 ? -4.664  16.897  7.006   1   65.66  ? 284 ASP B N   1 
ATOM   3290 C  CA  . ASP B 2 114 ? -4.506  17.156  8.431   1   65.9   ? 284 ASP B CA  1 
ATOM   3291 C  C   . ASP B 2 114 ? -5.647  17.967  9.052   1   54.89  ? 284 ASP B C   1 
ATOM   3292 O  O   . ASP B 2 114 ? -5.429  18.755  9.968   1   43.94  ? 284 ASP B O   1 
ATOM   3293 C  CB  . ASP B 2 114 ? -3.141  17.845  8.683   1   68.21  ? 284 ASP B CB  1 
ATOM   3294 C  CG  . ASP B 2 114 ? -1.933  17.107  8.119   1   69.88  ? 284 ASP B CG  1 
ATOM   3295 O  OD1 . ASP B 2 114 ? -1.737  15.916  8.474   1   71.4   ? 284 ASP B OD1 1 
ATOM   3296 O  OD2 . ASP B 2 114 ? -1.188  17.716  7.329   1   67.04  ? 284 ASP B OD2 1 
ATOM   3297 N  N   . THR B 2 115 ? -6.877  17.753  8.567   1   52.13  ? 285 THR B N   1 
ATOM   3298 C  CA  . THR B 2 115 ? -8.059  18.235  9.263   1   51.72  ? 285 THR B CA  1 
ATOM   3299 C  C   . THR B 2 115 ? -8.109  17.564  10.637  1   49.28  ? 285 THR B C   1 
ATOM   3300 O  O   . THR B 2 115 ? -8.443  18.199  11.631  1   52.33  ? 285 THR B O   1 
ATOM   3301 C  CB  . THR B 2 115 ? -9.338  17.962  8.452   1   52.38  ? 285 THR B CB  1 
ATOM   3302 O  OG1 . THR B 2 115 ? -9.146  18.358  7.102   1   52.73  ? 285 THR B OG1 1 
ATOM   3303 C  CG2 . THR B 2 115 ? -10.55  18.685  9.019   1   50.73  ? 285 THR B CG2 1 
ATOM   3304 N  N   . TYR B 2 116 ? -7.754  16.274  10.674  1   44.73  ? 286 TYR B N   1 
ATOM   3305 C  CA  . TYR B 2 116 ? -7.795  15.479  11.889  1   39.52  ? 286 TYR B CA  1 
ATOM   3306 C  C   . TYR B 2 116 ? -6.409  14.983  12.279  1   36.55  ? 286 TYR B C   1 
ATOM   3307 O  O   . TYR B 2 116 ? -5.498  14.977  11.46   1   41.41  ? 286 TYR B O   1 
ATOM   3308 C  CB  . TYR B 2 116 ? -8.74   14.291  11.704  1   37.76  ? 286 TYR B CB  1 
ATOM   3309 C  CG  . TYR B 2 116 ? -10.088 14.709  11.163  1   35.39  ? 286 TYR B CG  1 
ATOM   3310 C  CD1 . TYR B 2 116 ? -10.955 15.482  11.922  1   33.52  ? 286 TYR B CD1 1 
ATOM   3311 C  CD2 . TYR B 2 116 ? -10.484 14.356  9.882   1   34.74  ? 286 TYR B CD2 1 
ATOM   3312 C  CE1 . TYR B 2 116 ? -12.19  15.883  11.423  1   32.47  ? 286 TYR B CE1 1 
ATOM   3313 C  CE2 . TYR B 2 116 ? -11.716 14.747  9.373   1   34.36  ? 286 TYR B CE2 1 
ATOM   3314 C  CZ  . TYR B 2 116 ? -12.565 15.519  10.143  1   33.6   ? 286 TYR B CZ  1 
ATOM   3315 O  OH  . TYR B 2 116 ? -13.791 15.891  9.642   1   34.8   ? 286 TYR B OH  1 
ATOM   3316 N  N   . THR B 2 117 ? -6.265  14.619  13.555  1   34.35  ? 287 THR B N   1 
ATOM   3317 C  CA  . THR B 2 117 ? -5.062  13.988  14.068  1   35.33  ? 287 THR B CA  1 
ATOM   3318 C  C   . THR B 2 117 ? -5.157  12.468  13.973  1   36.72  ? 287 THR B C   1 
ATOM   3319 O  O   . THR B 2 117 ? -6.243  11.911  13.854  1   32.01  ? 287 THR B O   1 
ATOM   3320 C  CB  . THR B 2 117 ? -4.835  14.368  15.526  1   34.06  ? 287 THR B CB  1 
ATOM   3321 O  OG1 . THR B 2 117 ? -5.943  13.879  16.272  1   32.76  ? 287 THR B OG1 1 
ATOM   3322 C  CG2 . THR B 2 117 ? -4.671  15.867  15.721  1   32.38  ? 287 THR B CG2 1 
ATOM   3323 N  N   . LYS B 2 118 ? -4.004  11.805  14.073  1   38.45  ? 288 LYS B N   1 
ATOM   3324 C  CA  . LYS B 2 118 ? -3.952  10.355  14.079  1   39.85  ? 288 LYS B CA  1 
ATOM   3325 C  C   . LYS B 2 118 ? -4.765  9.799   15.245  1   36.08  ? 288 LYS B C   1 
ATOM   3326 O  O   . LYS B 2 118 ? -5.477  8.815   15.081  1   35.8   ? 288 LYS B O   1 
ATOM   3327 C  CB  . LYS B 2 118 ? -2.491  9.898   14.138  1   45.25  ? 288 LYS B CB  1 
ATOM   3328 C  CG  . LYS B 2 118 ? -2.272  8.402   14.217  1   51.52  ? 288 LYS B CG  1 
ATOM   3329 C  CD  . LYS B 2 118 ? -0.799  8.062   14.202  1   59.41  ? 288 LYS B CD  1 
ATOM   3330 C  CE  . LYS B 2 118 ? -0.531  6.633   14.61   1   67.69  ? 288 LYS B CE  1 
ATOM   3331 N  NZ  . LYS B 2 118 ? 0.911   6.411   14.893  1   71.88  ? 288 LYS B NZ  1 
ATOM   3332 N  N   . LYS B 2 119 ? -4.672  10.448  16.409  1   33.57  ? 289 LYS B N   1 
ATOM   3333 C  CA  . LYS B 2 119 ? -5.399  10.011  17.59   1   35.43  ? 289 LYS B CA  1 
ATOM   3334 C  C   . LYS B 2 119 ? -6.911  10.066  17.373  1   34.11  ? 289 LYS B C   1 
ATOM   3335 O  O   . LYS B 2 119 ? -7.629  9.178   17.823  1   32.45  ? 289 LYS B O   1 
ATOM   3336 C  CB  . LYS B 2 119 ? -4.989  10.872  18.781  1   39.11  ? 289 LYS B CB  1 
ATOM   3337 C  CG  . LYS B 2 119 ? -5.554  10.441  20.106  1   44.8   ? 289 LYS B CG  1 
ATOM   3338 C  CD  . LYS B 2 119 ? -4.864  11.156  21.266  1   49.36  ? 289 LYS B CD  1 
ATOM   3339 C  CE  . LYS B 2 119 ? -5.412  10.761  22.628  1   54.98  ? 289 LYS B CE  1 
ATOM   3340 N  NZ  . LYS B 2 119 ? -6.774  11.324  22.87   1   56.52  ? 289 LYS B NZ  1 
ATOM   3341 N  N   . GLN B 2 120 ? -7.386  11.107  16.678  1   31.06  ? 290 GLN B N   1 
ATOM   3342 C  CA  . GLN B 2 120 ? -8.8    11.224  16.366  1   29.86  ? 290 GLN B CA  1 
ATOM   3343 C  C   . GLN B 2 120 ? -9.27   10.101  15.447  1   26.76  ? 290 GLN B C   1 
ATOM   3344 O  O   . GLN B 2 120 ? -10.358 9.562   15.628  1   25.34  ? 290 GLN B O   1 
ATOM   3345 C  CB  . GLN B 2 120 ? -9.12   12.575  15.717  1   30.17  ? 290 GLN B CB  1 
ATOM   3346 C  CG  . GLN B 2 120 ? -9.148  13.722  16.699  1   32.21  ? 290 GLN B CG  1 
ATOM   3347 C  CD  . GLN B 2 120 ? -9.397  15.036  15.996  1   33.15  ? 290 GLN B CD  1 
ATOM   3348 O  OE1 . GLN B 2 120 ? -8.665  15.416  15.065  1   34.14  ? 290 GLN B OE1 1 
ATOM   3349 N  NE2 . GLN B 2 120 ? -10.446 15.744  16.408  1   31.02  ? 290 GLN B NE2 1 
ATOM   3350 N  N   . VAL B 2 121 ? -8.459  9.779   14.438  1   27.83  ? 291 VAL B N   1 
ATOM   3351 C  CA  . VAL B 2 121 ? -8.784  8.702   13.522  1   30.04  ? 291 VAL B CA  1 
ATOM   3352 C  C   . VAL B 2 121 ? -8.895  7.385   14.294  1   30.04  ? 291 VAL B C   1 
ATOM   3353 O  O   . VAL B 2 121 ? -9.864  6.65    14.123  1   27.86  ? 291 VAL B O   1 
ATOM   3354 C  CB  . VAL B 2 121 ? -7.769  8.619   12.363  1   30     ? 291 VAL B CB  1 
ATOM   3355 C  CG1 . VAL B 2 121 ? -7.954  7.342   11.543  1   31.38  ? 291 VAL B CG1 1 
ATOM   3356 C  CG2 . VAL B 2 121 ? -7.871  9.847   11.48   1   30.86  ? 291 VAL B CG2 1 
ATOM   3357 N  N   . LEU B 2 122 ? -7.914  7.106   15.158  1   30.04  ? 292 LEU B N   1 
ATOM   3358 C  CA  . LEU B 2 122 ? -7.899  5.861   15.907  1   33.13  ? 292 LEU B CA  1 
ATOM   3359 C  C   . LEU B 2 122 ? -9.056  5.77    16.892  1   33.54  ? 292 LEU B C   1 
ATOM   3360 O  O   . LEU B 2 122 ? -9.641  4.704   17.03   1   33.5   ? 292 LEU B O   1 
ATOM   3361 C  CB  . LEU B 2 122 ? -6.565  5.673   16.654  1   33.38  ? 292 LEU B CB  1 
ATOM   3362 C  CG  . LEU B 2 122 ? -5.343  5.445   15.744  1   34.53  ? 292 LEU B CG  1 
ATOM   3363 C  CD1 . LEU B 2 122 ? -4.176  4.921   16.525  1   32.68  ? 292 LEU B CD1 1 
ATOM   3364 C  CD2 . LEU B 2 122 ? -5.675  4.489   14.577  1   34.03  ? 292 LEU B CD2 1 
ATOM   3365 N  N   . ARG B 2 123 ? -9.432  6.888   17.503  1   33.8   ? 293 ARG B N   1 
ATOM   3366 C  CA  . ARG B 2 123 ? -10.552 6.892   18.479  1   35.24  ? 293 ARG B CA  1 
ATOM   3367 C  C   . ARG B 2 123 ? -11.877 6.72    17.728  1   30.49  ? 293 ARG B C   1 
ATOM   3368 O  O   . ARG B 2 123 ? -12.762 6.042   18.254  1   30.71  ? 293 ARG B O   1 
ATOM   3369 C  CB  . ARG B 2 123 ? -10.494 8.169   19.32   1   39.44  ? 293 ARG B CB  1 
ATOM   3370 C  CG  . ARG B 2 123 ? -9.466  8.155   20.441  1   42.93  ? 293 ARG B CG  1 
ATOM   3371 C  CD  . ARG B 2 123 ? -9.683  9.338   21.364  1   51.26  ? 293 ARG B CD  1 
ATOM   3372 N  NE  . ARG B 2 123 ? -9.755  8.978   22.784  1   58.01  ? 293 ARG B NE  1 
ATOM   3373 C  CZ  . ARG B 2 123 ? -10.377 7.918   23.287  1   64.87  ? 293 ARG B CZ  1 
ATOM   3374 N  NH1 . ARG B 2 123 ? -11.625 7.653   22.949  1   66.46  ? 293 ARG B NH1 1 
ATOM   3375 N  NH2 . ARG B 2 123 ? -9.747  7.133   24.142  1   62.61  ? 293 ARG B NH2 1 
ATOM   3376 N  N   . MET B 2 124 ? -11.991 7.312   16.544  1   30.63  ? 294 MET B N   1 
ATOM   3377 C  CA  . MET B 2 124 ? -13.189 7.14    15.736  1   31.21  ? 294 MET B CA  1 
ATOM   3378 C  C   . MET B 2 124 ? -13.284 5.702   15.236  1   27.81  ? 294 MET B C   1 
ATOM   3379 O  O   . MET B 2 124 ? -14.373 5.142   15.198  1   25.52  ? 294 MET B O   1 
ATOM   3380 C  CB  . MET B 2 124 ? -13.22  8.108   14.539  1   31.06  ? 294 MET B CB  1 
ATOM   3381 C  CG  . MET B 2 124 ? -14.474 7.972   13.668  1   30.26  ? 294 MET B CG  1 
ATOM   3382 S  SD  . MET B 2 124 ? -16.041 8.408   14.502  1   31.93  ? 294 MET B SD  1 
ATOM   3383 C  CE  . MET B 2 124 ? -15.947 10.237  14.481  1   30.88  ? 294 MET B CE  1 
ATOM   3384 N  N   . GLU B 2 125 ? -12.155 5.079   14.913  1   30.16  ? 295 GLU B N   1 
ATOM   3385 C  CA  . GLU B 2 125 ? -12.163 3.65    14.502  1   30.73  ? 295 GLU B CA  1 
ATOM   3386 C  C   . GLU B 2 125 ? -12.788 2.809   15.621  1   31.16  ? 295 GLU B C   1 
ATOM   3387 O  O   . GLU B 2 125 ? -13.638 1.955   15.319  1   28.79  ? 295 GLU B O   1 
ATOM   3388 C  CB  . GLU B 2 125 ? -10.753 3.164   14.172  1   30.94  ? 295 GLU B CB  1 
ATOM   3389 C  CG  . GLU B 2 125 ? -10.604 1.647   14.172  1   30.22  ? 295 GLU B CG  1 
ATOM   3390 C  CD  . GLU B 2 125 ? -9.209  1.149   13.85   1   29.51  ? 295 GLU B CD  1 
ATOM   3391 O  OE1 . GLU B 2 125 ? -8.395  1.026   14.78   1   28.58  ? 295 GLU B OE1 1 
ATOM   3392 O  OE2 . GLU B 2 125 ? -8.939  0.879   12.669  1   31.48  ? 295 GLU B OE2 1 
ATOM   3393 N  N   . HIS B 2 126 ? -12.383 3.065   16.861  1   31.12  ? 296 HIS B N   1 
ATOM   3394 C  CA  . HIS B 2 126 ? -12.935 2.326   18.022  1   36.38  ? 296 HIS B CA  1 
ATOM   3395 C  C   . HIS B 2 126 ? -14.437 2.594   18.109  1   33.71  ? 296 HIS B C   1 
ATOM   3396 O  O   . HIS B 2 126 ? -15.205 1.639   18.268  1   36.31  ? 296 HIS B O   1 
ATOM   3397 C  CB  . HIS B 2 126 ? -12.144 2.705   19.277  1   44.31  ? 296 HIS B CB  1 
ATOM   3398 C  CG  . HIS B 2 126 ? -12.625 2.181   20.591  1   65.6   ? 296 HIS B CG  1 
ATOM   3399 N  ND1 . HIS B 2 126 ? -13.941 1.993   20.956  1   84.64  ? 296 HIS B ND1 1 
ATOM   3400 C  CD2 . HIS B 2 126 ? -11.9   1.84    21.662  1   80.81  ? 296 HIS B CD2 1 
ATOM   3401 C  CE1 . HIS B 2 126 ? -13.994 1.535   22.197  1   83.76  ? 296 HIS B CE1 1 
ATOM   3402 N  NE2 . HIS B 2 126 ? -12.763 1.432   22.644  1   88.47  ? 296 HIS B NE2 1 
ATOM   3403 N  N   . LEU B 2 127 ? -14.836 3.858   18.022  1   28.68  ? 297 LEU B N   1 
ATOM   3404 C  CA  . LEU B 2 127 ? -16.268 4.201   18.167  1   27.27  ? 297 LEU B CA  1 
ATOM   3405 C  C   . LEU B 2 127 ? -17.058 3.479   17.072  1   26.18  ? 297 LEU B C   1 
ATOM   3406 O  O   . LEU B 2 127 ? -18.109 2.908   17.373  1   24.54  ? 297 LEU B O   1 
ATOM   3407 C  CB  . LEU B 2 127 ? -16.478 5.711   18.116  1   26.08  ? 297 LEU B CB  1 
ATOM   3408 C  CG  . LEU B 2 127 ? -17.925 6.195   18.236  1   23.43  ? 297 LEU B CG  1 
ATOM   3409 C  CD1 . LEU B 2 127 ? -18.511 5.789   19.573  1   22.91  ? 297 LEU B CD1 1 
ATOM   3410 C  CD2 . LEU B 2 127 ? -17.998 7.695   18.051  1   24.26  ? 297 LEU B CD2 1 
ATOM   3411 N  N   . VAL B 2 128 ? -16.546 3.516   15.848  1   27.12  ? 298 VAL B N   1 
ATOM   3412 C  CA  . VAL B 2 128 ? -17.267 2.854   14.772  1   29.68  ? 298 VAL B CA  1 
ATOM   3413 C  C   . VAL B 2 128 ? -17.394 1.353   15.04   1   30.17  ? 298 VAL B C   1 
ATOM   3414 O  O   . VAL B 2 128 ? -18.461 0.784   14.84   1   31.12  ? 298 VAL B O   1 
ATOM   3415 C  CB  . VAL B 2 128 ? -16.646 3.135   13.396  1   33.05  ? 298 VAL B CB  1 
ATOM   3416 C  CG1 . VAL B 2 128 ? -17.293 2.281   12.313  1   36.88  ? 298 VAL B CG1 1 
ATOM   3417 C  CG2 . VAL B 2 128 ? -16.754 4.606   13.035  1   34.89  ? 298 VAL B CG2 1 
ATOM   3418 N  N   . LEU B 2 129 ? -16.325 0.718   15.535  1   30.35  ? 299 LEU B N   1 
ATOM   3419 C  CA  . LEU B 2 129 ? -16.38  -0.696  15.868  1   28.35  ? 299 LEU B CA  1 
ATOM   3420 C  C   . LEU B 2 129 ? -17.403 -0.954  16.972  1   27.27  ? 299 LEU B C   1 
ATOM   3421 O  O   . LEU B 2 129 ? -18.12  -1.953  16.94   1   27.83  ? 299 LEU B O   1 
ATOM   3422 C  CB  . LEU B 2 129 ? -14.997 -1.239  16.282  1   28.17  ? 299 LEU B CB  1 
ATOM   3423 C  CG  . LEU B 2 129 ? -13.961 -1.424  15.148  1   27.7   ? 299 LEU B CG  1 
ATOM   3424 C  CD1 . LEU B 2 129 ? -12.598 -1.785  15.718  1   27.92  ? 299 LEU B CD1 1 
ATOM   3425 C  CD2 . LEU B 2 129 ? -14.383 -2.486  14.177  1   26.17  ? 299 LEU B CD2 1 
ATOM   3426 N  N   . LYS B 2 130 ? -17.483 -0.052  17.947  1   28.9   ? 300 LYS B N   1 
ATOM   3427 C  CA  . LYS B 2 130 ? -18.429 -0.22   19.041  1   34.11  ? 300 LYS B CA  1 
ATOM   3428 C  C   . LYS B 2 130 ? -19.859 -0.13   18.503  1   32.99  ? 300 LYS B C   1 
ATOM   3429 O  O   . LYS B 2 130 ? -20.687 -0.987  18.796  1   33.39  ? 300 LYS B O   1 
ATOM   3430 C  CB  . LYS B 2 130 ? -18.183 0.808   20.169  1   36.96  ? 300 LYS B CB  1 
ATOM   3431 C  CG  . LYS B 2 130 ? -19.293 0.843   21.229  1   44.07  ? 300 LYS B CG  1 
ATOM   3432 C  CD  . LYS B 2 130 ? -19.306 2.12    22.126  1   46.08  ? 300 LYS B CD  1 
ATOM   3433 C  CE  . LYS B 2 130 ? -20.523 2.139   23.028  1   46.71  ? 300 LYS B CE  1 
ATOM   3434 N  NZ  . LYS B 2 130 ? -20.798 3.482   23.617  1   45.55  ? 300 LYS B NZ  1 
ATOM   3435 N  N   . VAL B 2 131 ? -20.13  0.894   17.688  1   32.41  ? 301 VAL B N   1 
ATOM   3436 C  CA  . VAL B 2 131 ? -21.463 1.132   17.161  1   32.43  ? 301 VAL B CA  1 
ATOM   3437 C  C   . VAL B 2 131 ? -21.944 0.005   16.246  1   31.5   ? 301 VAL B C   1 
ATOM   3438 O  O   . VAL B 2 131 ? -23.116 -0.346  16.282  1   33.9   ? 301 VAL B O   1 
ATOM   3439 C  CB  . VAL B 2 131 ? -21.502 2.516   16.445  1   34.76  ? 301 VAL B CB  1 
ATOM   3440 C  CG1 . VAL B 2 131 ? -22.745 2.671   15.562  1   34.28  ? 301 VAL B CG1 1 
ATOM   3441 C  CG2 . VAL B 2 131 ? -21.391 3.666   17.453  1   32.91  ? 301 VAL B CG2 1 
ATOM   3442 N  N   . LEU B 2 132 ? -21.049 -0.555  15.419  1   29.92  ? 302 LEU B N   1 
ATOM   3443 C  CA  . LEU B 2 132 ? -21.399 -1.652  14.533  1   29.5   ? 302 LEU B CA  1 
ATOM   3444 C  C   . LEU B 2 132 ? -21.28  -3.008  15.22   1   31.65  ? 302 LEU B C   1 
ATOM   3445 O  O   . LEU B 2 132 ? -21.515 -4.041  14.594  1   36.15  ? 302 LEU B O   1 
ATOM   3446 C  CB  . LEU B 2 132 ? -20.49  -1.619  13.293  1   30.56  ? 302 LEU B CB  1 
ATOM   3447 C  CG  . LEU B 2 132 ? -20.549 -0.342  12.446  1   33.63  ? 302 LEU B CG  1 
ATOM   3448 C  CD1 . LEU B 2 132 ? -19.763 -0.489  11.18   1   34.12  ? 302 LEU B CD1 1 
ATOM   3449 C  CD2 . LEU B 2 132 ? -22.004 0.068   12.082  1   35.14  ? 302 LEU B CD2 1 
ATOM   3450 N  N   . ALA B 2 133 ? -20.869 -2.998  16.496  1   31.95  ? 303 ALA B N   1 
ATOM   3451 C  CA  . ALA B 2 133 ? -20.551 -4.207  17.245  1   31.37  ? 303 ALA B CA  1 
ATOM   3452 C  C   . ALA B 2 133 ? -19.693 -5.202  16.459  1   29.85  ? 303 ALA B C   1 
ATOM   3453 O  O   . ALA B 2 133 ? -19.886 -6.407  16.577  1   25.23  ? 303 ALA B O   1 
ATOM   3454 C  CB  . ALA B 2 133 ? -21.831 -4.876  17.743  1   28.78  ? 303 ALA B CB  1 
ATOM   3455 N  N   . PHE B 2 134 ? -18.717 -4.67   15.707  1   32.19  ? 304 PHE B N   1 
ATOM   3456 C  CA  . PHE B 2 134 ? -17.813 -5.436  14.858  1   33.98  ? 304 PHE B CA  1 
ATOM   3457 C  C   . PHE B 2 134 ? -18.467 -6.256  13.741  1   36.63  ? 304 PHE B C   1 
ATOM   3458 O  O   . PHE B 2 134 ? -17.816 -7.138  13.188  1   34.24  ? 304 PHE B O   1 
ATOM   3459 C  CB  . PHE B 2 134 ? -16.929 -6.403  15.697  1   35.86  ? 304 PHE B CB  1 
ATOM   3460 C  CG  . PHE B 2 134 ? -15.832 -5.795  16.547  1   35.69  ? 304 PHE B CG  1 
ATOM   3461 C  CD1 . PHE B 2 134 ? -16.118 -5.22   17.779  1   38.53  ? 304 PHE B CD1 1 
ATOM   3462 C  CD2 . PHE B 2 134 ? -14.521 -5.807  16.123  1   37.24  ? 304 PHE B CD2 1 
ATOM   3463 C  CE1 . PHE B 2 134 ? -15.11  -4.662  18.558  1   37.25  ? 304 PHE B CE1 1 
ATOM   3464 C  CE2 . PHE B 2 134 ? -13.514 -5.254  16.909  1   35.75  ? 304 PHE B CE2 1 
ATOM   3465 C  CZ  . PHE B 2 134 ? -13.813 -4.684  18.117  1   37.54  ? 304 PHE B CZ  1 
ATOM   3466 N  N   . ASP B 2 135 ? -19.727 -5.964  13.383  1   39.31  ? 305 ASP B N   1 
ATOM   3467 C  CA  . ASP B 2 135 ? -20.357 -6.62   12.245  1   38.17  ? 305 ASP B CA  1 
ATOM   3468 C  C   . ASP B 2 135 ? -19.903 -5.996  10.935  1   33.54  ? 305 ASP B C   1 
ATOM   3469 O  O   . ASP B 2 135 ? -20.621 -5.173  10.369  1   32.64  ? 305 ASP B O   1 
ATOM   3470 C  CB  . ASP B 2 135 ? -21.892 -6.547  12.302  1   43.18  ? 305 ASP B CB  1 
ATOM   3471 C  CG  . ASP B 2 135 ? -22.5   -7.625  13.131  1   52.32  ? 305 ASP B CG  1 
ATOM   3472 O  OD1 . ASP B 2 135 ? -21.916 -7.957  14.178  1   51.03  ? 305 ASP B OD1 1 
ATOM   3473 O  OD2 . ASP B 2 135 ? -23.561 -8.166  12.716  1   73.1   ? 305 ASP B OD2 1 
ATOM   3474 N  N   . LEU B 2 136 ? -18.717 -6.399  10.469  1   33.68  ? 306 LEU B N   1 
ATOM   3475 C  CA  . LEU B 2 136 ? -18.09  -5.766  9.32    1   35     ? 306 LEU B CA  1 
ATOM   3476 C  C   . LEU B 2 136 ? -18.201 -6.563  8.021   1   31.82  ? 306 LEU B C   1 
ATOM   3477 O  O   . LEU B 2 136 ? -18.053 -5.994  6.941   1   27.46  ? 306 LEU B O   1 
ATOM   3478 C  CB  . LEU B 2 136 ? -16.604 -5.486  9.625   1   40.23  ? 306 LEU B CB  1 
ATOM   3479 C  CG  . LEU B 2 136 ? -16.297 -4.512  10.797  1   41.71  ? 306 LEU B CG  1 
ATOM   3480 C  CD1 . LEU B 2 136 ? -14.956 -3.883  10.63   1   42     ? 306 LEU B CD1 1 
ATOM   3481 C  CD2 . LEU B 2 136 ? -17.321 -3.39   10.945  1   38.87  ? 306 LEU B CD2 1 
ATOM   3482 N  N   . ALA B 2 137 ? -18.47  -7.871  8.114   1   34.2   ? 307 ALA B N   1 
ATOM   3483 C  CA  . ALA B 2 137 ? -18.63  -8.695  6.921   1   33.35  ? 307 ALA B CA  1 
ATOM   3484 C  C   . ALA B 2 137 ? -20.006 -8.513  6.274   1   28.11  ? 307 ALA B C   1 
ATOM   3485 O  O   . ALA B 2 137 ? -20.78  -9.449  6.188   1   28.53  ? 307 ALA B O   1 
ATOM   3486 C  CB  . ALA B 2 137 ? -18.396 -10.157 7.273   1   34.32  ? 307 ALA B CB  1 
ATOM   3487 N  N   . ALA B 2 138 ? -20.292 -7.291  5.82    1   29.53  ? 308 ALA B N   1 
ATOM   3488 C  CA  . ALA B 2 138 ? -21.561 -6.934  5.221   1   33.27  ? 308 ALA B CA  1 
ATOM   3489 C  C   . ALA B 2 138 ? -21.582 -7.304  3.742   1   34.06  ? 308 ALA B C   1 
ATOM   3490 O  O   . ALA B 2 138 ? -20.587 -7.137  3.04    1   31.89  ? 308 ALA B O   1 
ATOM   3491 C  CB  . ALA B 2 138 ? -21.808 -5.43   5.354   1   34.76  ? 308 ALA B CB  1 
ATOM   3492 N  N   . PRO B 2 139 ? -22.73  -7.782  3.223   1   33.93  ? 309 PRO B N   1 
ATOM   3493 C  CA  . PRO B 2 139 ? -22.904 -7.954  1.787   1   31.93  ? 309 PRO B CA  1 
ATOM   3494 C  C   . PRO B 2 139 ? -22.926 -6.616  1.06    1   32.69  ? 309 PRO B C   1 
ATOM   3495 O  O   . PRO B 2 139 ? -23.546 -5.663  1.518   1   37.2   ? 309 PRO B O   1 
ATOM   3496 C  CB  . PRO B 2 139 ? -24.254 -8.682  1.686   1   34.75  ? 309 PRO B CB  1 
ATOM   3497 C  CG  . PRO B 2 139 ? -24.517 -9.218  3.055   1   33.45  ? 309 PRO B CG  1 
ATOM   3498 C  CD  . PRO B 2 139 ? -23.902 -8.242  3.989   1   34.35  ? 309 PRO B CD  1 
ATOM   3499 N  N   . THR B 2 140 ? -22.247 -6.583  -0.089  1   34.12  ? 310 THR B N   1 
ATOM   3500 C  CA  . THR B 2 140 ? -22.186 -5.414  -0.943  1   32.13  ? 310 THR B CA  1 
ATOM   3501 C  C   . THR B 2 140 ? -22.878 -5.689  -2.275  1   32.97  ? 310 THR B C   1 
ATOM   3502 O  O   . THR B 2 140 ? -23.116 -6.836  -2.65   1   31.76  ? 310 THR B O   1 
ATOM   3503 C  CB  . THR B 2 140 ? -20.723 -5.032  -1.196  1   31.34  ? 310 THR B CB  1 
ATOM   3504 O  OG1 . THR B 2 140 ? -20.083 -6.107  -1.902  1   30.55  ? 310 THR B OG1 1 
ATOM   3505 C  CG2 . THR B 2 140 ? -19.982 -4.74   0.08    1   29.9   ? 310 THR B CG2 1 
ATOM   3506 N  N   . ILE B 2 141 ? -23.156 -4.607  -3.004  1   32.19  ? 311 ILE B N   1 
ATOM   3507 C  CA  . ILE B 2 141 ? -23.598 -4.712  -4.38   1   33.4   ? 311 ILE B CA  1 
ATOM   3508 C  C   . ILE B 2 141 ? -22.683 -5.651  -5.16   1   37.82  ? 311 ILE B C   1 
ATOM   3509 O  O   . ILE B 2 141 ? -23.173 -6.478  -5.935  1   38.53  ? 311 ILE B O   1 
ATOM   3510 C  CB  . ILE B 2 141 ? -23.676 -3.315  -5.027  1   34.06  ? 311 ILE B CB  1 
ATOM   3511 C  CG1 . ILE B 2 141 ? -24.86  -2.509  -4.417  1   33.88  ? 311 ILE B CG1 1 
ATOM   3512 C  CG2 . ILE B 2 141 ? -23.764 -3.408  -6.542  1   30.96  ? 311 ILE B CG2 1 
ATOM   3513 C  CD1 . ILE B 2 141 ? -24.843 -1.066  -4.697  1   34.67  ? 311 ILE B CD1 1 
ATOM   3514 N  N   . ASN B 2 142 ? -21.365 -5.53   -4.94   1   36.96  ? 312 ASN B N   1 
ATOM   3515 C  CA  . ASN B 2 142 ? -20.399 -6.272  -5.739  1   39.19  ? 312 ASN B CA  1 
ATOM   3516 C  C   . ASN B 2 142 ? -20.418 -7.777  -5.512  1   35.39  ? 312 ASN B C   1 
ATOM   3517 O  O   . ASN B 2 142 ? -20.254 -8.544  -6.462  1   36.73  ? 312 ASN B O   1 
ATOM   3518 C  CB  . ASN B 2 142 ? -18.989 -5.76   -5.529  1   41.38  ? 312 ASN B CB  1 
ATOM   3519 C  CG  . ASN B 2 142 ? -18.749 -4.52   -6.314  1   45.75  ? 312 ASN B CG  1 
ATOM   3520 O  OD1 . ASN B 2 142 ? -19.699 -3.812  -6.736  1   45.47  ? 312 ASN B OD1 1 
ATOM   3521 N  ND2 . ASN B 2 142 ? -17.478 -4.225  -6.52   1   45.86  ? 312 ASN B ND2 1 
ATOM   3522 N  N   . GLN B 2 143 ? -20.607 -8.183  -4.254  1   34.03  ? 313 GLN B N   1 
ATOM   3523 C  CA  . GLN B 2 143 ? -20.697 -9.595  -3.924  1   35.37  ? 313 GLN B CA  1 
ATOM   3524 C  C   . GLN B 2 143 ? -21.837 -10.268 -4.68   1   32.26  ? 313 GLN B C   1 
ATOM   3525 O  O   . GLN B 2 143 ? -21.738 -11.444 -5.02   1   34.66  ? 313 GLN B O   1 
ATOM   3526 C  CB  . GLN B 2 143 ? -20.882 -9.783  -2.402  1   35.34  ? 313 GLN B CB  1 
ATOM   3527 C  CG  . GLN B 2 143 ? -19.573 -9.589  -1.625  1   31.9   ? 313 GLN B CG  1 
ATOM   3528 C  CD  . GLN B 2 143 ? -19.777 -9.677  -0.126  1   32.48  ? 313 GLN B CD  1 
ATOM   3529 O  OE1 . GLN B 2 143 ? -20.174 -10.688 0.419   1   29.8   ? 313 GLN B OE1 1 
ATOM   3530 N  NE2 . GLN B 2 143 ? -19.482 -8.61   0.583   1   35.6   ? 313 GLN B NE2 1 
ATOM   3531 N  N   . PHE B 2 144 ? -22.926 -9.522  -4.914  1   33.41  ? 314 PHE B N   1 
ATOM   3532 C  CA  . PHE B 2 144 ? -24.056 -10.04  -5.669  1   29.39  ? 314 PHE B CA  1 
ATOM   3533 C  C   . PHE B 2 144 ? -23.735 -10.022 -7.161  1   28.36  ? 314 PHE B C   1 
ATOM   3534 O  O   . PHE B 2 144 ? -23.951 -11.024 -7.845  1   29.42  ? 314 PHE B O   1 
ATOM   3535 C  CB  . PHE B 2 144 ? -25.343 -9.27   -5.336  1   28.61  ? 314 PHE B CB  1 
ATOM   3536 C  CG  . PHE B 2 144 ? -25.915 -9.655  -3.996  1   30.83  ? 314 PHE B CG  1 
ATOM   3537 C  CD1 . PHE B 2 144 ? -26.545 -10.876 -3.818  1   33.99  ? 314 PHE B CD1 1 
ATOM   3538 C  CD2 . PHE B 2 144 ? -25.796 -8.812  -2.904  1   31.83  ? 314 PHE B CD2 1 
ATOM   3539 C  CE1 . PHE B 2 144 ? -27.063 -11.239 -2.574  1   32.99  ? 314 PHE B CE1 1 
ATOM   3540 C  CE2 . PHE B 2 144 ? -26.317 -9.175  -1.656  1   33.24  ? 314 PHE B CE2 1 
ATOM   3541 C  CZ  . PHE B 2 144 ? -26.959 -10.379 -1.503  1   31.68  ? 314 PHE B CZ  1 
ATOM   3542 N  N   . LEU B 2 145 ? -23.186 -8.895  -7.638  1   28.75  ? 315 LEU B N   1 
ATOM   3543 C  CA  . LEU B 2 145 ? -22.853 -8.715  -9.041  1   29.58  ? 315 LEU B CA  1 
ATOM   3544 C  C   . LEU B 2 145 ? -21.971 -9.835  -9.587  1   29.78  ? 315 LEU B C   1 
ATOM   3545 O  O   . LEU B 2 145 ? -22.278 -10.387 -10.644 1   28.62  ? 315 LEU B O   1 
ATOM   3546 C  CB  . LEU B 2 145 ? -22.126 -7.378  -9.275  1   30.72  ? 315 LEU B CB  1 
ATOM   3547 C  CG  . LEU B 2 145 ? -22.983 -6.148  -9.474  1   32.04  ? 315 LEU B CG  1 
ATOM   3548 C  CD1 . LEU B 2 145 ? -22.121 -4.958  -9.789  1   31.85  ? 315 LEU B CD1 1 
ATOM   3549 C  CD2 . LEU B 2 145 ? -23.971 -6.339  -10.561 1   32.29  ? 315 LEU B CD2 1 
ATOM   3550 N  N   . THR B 2 146 ? -20.884 -10.151 -8.87   1   26.82  ? 316 THR B N   1 
ATOM   3551 C  CA  . THR B 2 146 ? -19.938 -11.152 -9.331  1   27.62  ? 316 THR B CA  1 
ATOM   3552 C  C   . THR B 2 146 ? -20.606 -12.514 -9.5    1   27.38  ? 316 THR B C   1 
ATOM   3553 O  O   . THR B 2 146 ? -20.254 -13.257 -10.411 1   28.95  ? 316 THR B O   1 
ATOM   3554 C  CB  . THR B 2 146 ? -18.692 -11.247 -8.412  1   28.19  ? 316 THR B CB  1 
ATOM   3555 O  OG1 . THR B 2 146 ? -19.095 -11.654 -7.103  1   27.82  ? 316 THR B OG1 1 
ATOM   3556 C  CG2 . THR B 2 146 ? -17.906 -9.944  -8.351  1   27.06  ? 316 THR B CG2 1 
ATOM   3557 N  N   . GLN B 2 147 ? -21.575 -12.83  -8.629  1   28.49  ? 317 GLN B N   1 
ATOM   3558 C  CA  . GLN B 2 147 ? -22.348 -14.059 -8.77   1   29.84  ? 317 GLN B CA  1 
ATOM   3559 C  C   . GLN B 2 147 ? -23.273 -14.035 -9.981  1   30.65  ? 317 GLN B C   1 
ATOM   3560 O  O   . GLN B 2 147 ? -23.428 -15.046 -10.664 1   34.53  ? 317 GLN B O   1 
ATOM   3561 C  CB  . GLN B 2 147 ? -23.198 -14.329 -7.526  1   30.22  ? 317 GLN B CB  1 
ATOM   3562 C  CG  . GLN B 2 147 ? -22.393 -14.869 -6.385  1   32.18  ? 317 GLN B CG  1 
ATOM   3563 C  CD  . GLN B 2 147 ? -23.236 -15.257 -5.228  1   33.4   ? 317 GLN B CD  1 
ATOM   3564 O  OE1 . GLN B 2 147 ? -24.173 -16.046 -5.351  1   36.79  ? 317 GLN B OE1 1 
ATOM   3565 N  NE2 . GLN B 2 147 ? -22.908 -14.714 -4.081  1   36.97  ? 317 GLN B NE2 1 
ATOM   3566 N  N   . TYR B 2 148 ? -23.912 -12.883 -10.203 1   28.38  ? 318 TYR B N   1 
ATOM   3567 C  CA  . TYR B 2 148 ? -24.79  -12.694 -11.342 1   29.93  ? 318 TYR B CA  1 
ATOM   3568 C  C   . TYR B 2 148 ? -24.008 -12.785 -12.656 1   30.74  ? 318 TYR B C   1 
ATOM   3569 O  O   . TYR B 2 148 ? -24.541 -13.242 -13.664 1   28.05  ? 318 TYR B O   1 
ATOM   3570 C  CB  . TYR B 2 148 ? -25.49  -11.316 -11.263 1   29.82  ? 318 TYR B CB  1 
ATOM   3571 C  CG  . TYR B 2 148 ? -26.414 -11.041 -10.091 1   30.65  ? 318 TYR B CG  1 
ATOM   3572 C  CD1 . TYR B 2 148 ? -26.82  -12.059 -9.23   1   30.99  ? 318 TYR B CD1 1 
ATOM   3573 C  CD2 . TYR B 2 148 ? -26.886 -9.763  -9.847  1   32.29  ? 318 TYR B CD2 1 
ATOM   3574 C  CE1 . TYR B 2 148 ? -27.68  -11.801 -8.165  1   30.61  ? 318 TYR B CE1 1 
ATOM   3575 C  CE2 . TYR B 2 148 ? -27.743 -9.493  -8.792  1   32.77  ? 318 TYR B CE2 1 
ATOM   3576 C  CZ  . TYR B 2 148 ? -28.139 -10.511 -7.949  1   33.75  ? 318 TYR B CZ  1 
ATOM   3577 O  OH  . TYR B 2 148 ? -28.988 -10.195 -6.918  1   30.95  ? 318 TYR B OH  1 
ATOM   3578 N  N   . PHE B 2 149 ? -22.748 -12.327 -12.644 1   32.64  ? 319 PHE B N   1 
ATOM   3579 C  CA  . PHE B 2 149 ? -21.897 -12.359 -13.828 1   33.71  ? 319 PHE B CA  1 
ATOM   3580 C  C   . PHE B 2 149 ? -21.72  -13.772 -14.386 1   30.94  ? 319 PHE B C   1 
ATOM   3581 O  O   . PHE B 2 149 ? -21.623 -13.951 -15.599 1   31.7   ? 319 PHE B O   1 
ATOM   3582 C  CB  . PHE B 2 149 ? -20.515 -11.751 -13.537 1   31.3   ? 319 PHE B CB  1 
ATOM   3583 C  CG  . PHE B 2 149 ? -20.458 -10.26  -13.321 1   32.53  ? 319 PHE B CG  1 
ATOM   3584 C  CD1 . PHE B 2 149 ? -21.561 -9.454  -13.583 1   35.55  ? 319 PHE B CD1 1 
ATOM   3585 C  CD2 . PHE B 2 149 ? -19.299 -9.657  -12.852 1   30.66  ? 319 PHE B CD2 1 
ATOM   3586 C  CE1 . PHE B 2 149 ? -21.5   -8.081  -13.389 1   31.68  ? 319 PHE B CE1 1 
ATOM   3587 C  CE2 . PHE B 2 149 ? -19.24  -8.285  -12.661 1   29.92  ? 319 PHE B CE2 1 
ATOM   3588 C  CZ  . PHE B 2 149 ? -20.341 -7.506  -12.929 1   32.5   ? 319 PHE B CZ  1 
ATOM   3589 N  N   . LEU B 2 150 ? -21.747 -14.77  -13.499 1   30.84  ? 320 LEU B N   1 
ATOM   3590 C  CA  . LEU B 2 150 ? -21.631 -16.165 -13.899 1   31.8   ? 320 LEU B CA  1 
ATOM   3591 C  C   . LEU B 2 150 ? -22.799 -16.683 -14.742 1   34.06  ? 320 LEU B C   1 
ATOM   3592 O  O   . LEU B 2 150 ? -22.736 -17.794 -15.262 1   36.37  ? 320 LEU B O   1 
ATOM   3593 C  CB  . LEU B 2 150 ? -21.482 -17.03  -12.632 1   31.94  ? 320 LEU B CB  1 
ATOM   3594 C  CG  . LEU B 2 150 ? -20.24  -16.695 -11.774 1   32.39  ? 320 LEU B CG  1 
ATOM   3595 C  CD1 . LEU B 2 150 ? -20.276 -17.434 -10.426 1   30.28  ? 320 LEU B CD1 1 
ATOM   3596 C  CD2 . LEU B 2 150 ? -18.921 -16.963 -12.585 1   30.12  ? 320 LEU B CD2 1 
ATOM   3597 N  N   . HIS B 2 151 ? -23.867 -15.889 -14.876 1   33.38  ? 321 HIS B N   1 
ATOM   3598 C  CA  . HIS B 2 151 ? -24.985 -16.266 -15.725 1   37.3   ? 321 HIS B CA  1 
ATOM   3599 C  C   . HIS B 2 151 ? -24.955 -15.65  -17.128 1   37.54  ? 321 HIS B C   1 
ATOM   3600 O  O   . HIS B 2 151 ? -25.862 -15.876 -17.921 1   42.25  ? 321 HIS B O   1 
ATOM   3601 C  CB  . HIS B 2 151 ? -26.305 -15.92  -15.017 1   35.22  ? 321 HIS B CB  1 
ATOM   3602 C  CG  . HIS B 2 151 ? -26.567 -16.742 -13.79  1   35.18  ? 321 HIS B CG  1 
ATOM   3603 N  ND1 . HIS B 2 151 ? -27.593 -17.665 -13.746 1   33.38  ? 321 HIS B ND1 1 
ATOM   3604 C  CD2 . HIS B 2 151 ? -25.913 -16.771 -12.608 1   34.36  ? 321 HIS B CD2 1 
ATOM   3605 C  CE1 . HIS B 2 151 ? -27.54  -18.218 -12.544 1   29.76  ? 321 HIS B CE1 1 
ATOM   3606 N  NE2 . HIS B 2 151 ? -26.545 -17.707 -11.826 1   31.12  ? 321 HIS B NE2 1 
ATOM   3607 N  N   A GLN B 2 152 ? -23.912 -14.875 -17.431 0.5 38.01  ? 322 GLN B N   1 
ATOM   3608 N  N   B GLN B 2 152 ? -23.913 -14.871 -17.436 0.5 39.22  ? 322 GLN B N   1 
ATOM   3609 C  CA  A GLN B 2 152 ? -23.692 -14.382 -18.779 0.5 38.02  ? 322 GLN B CA  1 
ATOM   3610 C  CA  B GLN B 2 152 ? -23.724 -14.374 -18.79  0.5 40.12  ? 322 GLN B CA  1 
ATOM   3611 C  C   A GLN B 2 152 ? -23.378 -15.529 -19.738 0.5 45.94  ? 322 GLN B C   1 
ATOM   3612 C  C   B GLN B 2 152 ? -23.374 -15.518 -19.739 0.5 47.4   ? 322 GLN B C   1 
ATOM   3613 O  O   A GLN B 2 152 ? -22.697 -16.481 -19.357 0.5 46.96  ? 322 GLN B O   1 
ATOM   3614 O  O   B GLN B 2 152 ? -22.693 -16.467 -19.351 0.5 48.37  ? 322 GLN B O   1 
ATOM   3615 C  CB  A GLN B 2 152 ? -22.52  -13.417 -18.806 0.5 34.33  ? 322 GLN B CB  1 
ATOM   3616 C  CB  B GLN B 2 152 ? -22.646 -13.286 -18.856 0.5 37.83  ? 322 GLN B CB  1 
ATOM   3617 C  CG  A GLN B 2 152 ? -22.773 -12.083 -18.196 0.5 30.85  ? 322 GLN B CG  1 
ATOM   3618 C  CG  B GLN B 2 152 ? -23.254 -11.883 -18.958 0.5 35.7   ? 322 GLN B CG  1 
ATOM   3619 C  CD  A GLN B 2 152 ? -21.494 -11.303 -18.126 0.5 27.28  ? 322 GLN B CD  1 
ATOM   3620 C  CD  B GLN B 2 152 ? -23.697 -11.549 -20.38  0.5 33.6   ? 322 GLN B CD  1 
ATOM   3621 O  OE1 A GLN B 2 152 ? -21.253 -10.42  -18.944 0.5 25.14  ? 322 GLN B OE1 1 
ATOM   3622 O  OE1 B GLN B 2 152 ? -24.601 -12.195 -20.963 0.5 29.03  ? 322 GLN B OE1 1 
ATOM   3623 N  NE2 A GLN B 2 152 ? -20.637 -11.664 -17.181 0.5 24.3   ? 322 GLN B NE2 1 
ATOM   3624 N  NE2 B GLN B 2 152 ? -23.054 -10.53  -20.968 0.5 29.49  ? 322 GLN B NE2 1 
ATOM   3625 N  N   . GLN B 2 153 ? -23.858 -15.402 -20.983 1   51.37  ? 323 GLN B N   1 
ATOM   3626 C  CA  . GLN B 2 153 ? -23.607 -16.383 -22.029 1   57.5   ? 323 GLN B CA  1 
ATOM   3627 C  C   . GLN B 2 153 ? -23.331 -15.701 -23.369 1   57.49  ? 323 GLN B C   1 
ATOM   3628 O  O   . GLN B 2 153 ? -24.266 -15.373 -24.095 1   51.58  ? 323 GLN B O   1 
ATOM   3629 C  CB  . GLN B 2 153 ? -24.808 -17.343 -22.162 1   64.64  ? 323 GLN B CB  1 
ATOM   3630 C  CG  . GLN B 2 153 ? -24.671 -18.543 -21.244 1   73.08  ? 323 GLN B CG  1 
ATOM   3631 C  CD  . GLN B 2 153 ? -25.949 -19.322 -21.096 1   76.63  ? 323 GLN B CD  1 
ATOM   3632 O  OE1 . GLN B 2 153 ? -26.706 -19.521 -22.051 1   83.8   ? 323 GLN B OE1 1 
ATOM   3633 N  NE2 . GLN B 2 153 ? -26.213 -19.759 -19.882 1   78.85  ? 323 GLN B NE2 1 
ATOM   3634 N  N   . PRO B 2 154 ? -22.056 -15.45  -23.753 1   53.27  ? 324 PRO B N   1 
ATOM   3635 C  CA  . PRO B 2 154 ? -20.886 -15.703 -22.907 1   47.51  ? 324 PRO B CA  1 
ATOM   3636 C  C   . PRO B 2 154 ? -20.573 -14.495 -22.029 1   41.96  ? 324 PRO B C   1 
ATOM   3637 O  O   . PRO B 2 154 ? -21.29  -13.496 -22.082 1   39.02  ? 324 PRO B O   1 
ATOM   3638 C  CB  . PRO B 2 154 ? -19.789 -15.93  -23.937 1   47.47  ? 324 PRO B CB  1 
ATOM   3639 C  CG  . PRO B 2 154 ? -20.162 -14.957 -25.051 1   47.77  ? 324 PRO B CG  1 
ATOM   3640 C  CD  . PRO B 2 154 ? -21.679 -14.871 -25.054 1   47.46  ? 324 PRO B CD  1 
ATOM   3641 N  N   . ALA B 2 155 ? -19.484 -14.596 -21.253 1   36.93  ? 325 ALA B N   1 
ATOM   3642 C  CA  . ALA B 2 155 ? -19.001 -13.487 -20.444 1   36.11  ? 325 ALA B CA  1 
ATOM   3643 C  C   . ALA B 2 155 ? -18.629 -12.305 -21.338 1   36.88  ? 325 ALA B C   1 
ATOM   3644 O  O   . ALA B 2 155 ? -18.079 -12.501 -22.42  1   38.65  ? 325 ALA B O   1 
ATOM   3645 C  CB  . ALA B 2 155 ? -17.802 -13.912 -19.616 1   32.6   ? 325 ALA B CB  1 
ATOM   3646 N  N   . ASN B 2 156 ? -18.954 -11.086 -20.883 1   35.61  ? 326 ASN B N   1 
ATOM   3647 C  CA  . ASN B 2 156 ? -18.63  -9.872  -21.613 1   36.47  ? 326 ASN B CA  1 
ATOM   3648 C  C   . ASN B 2 156 ? -18.129 -8.829  -20.622 1   36.96  ? 326 ASN B C   1 
ATOM   3649 O  O   . ASN B 2 156 ? -18.857 -8.46   -19.703 1   40.19  ? 326 ASN B O   1 
ATOM   3650 C  CB  . ASN B 2 156 ? -19.844 -9.34   -22.408 1   36.38  ? 326 ASN B CB  1 
ATOM   3651 C  CG  . ASN B 2 156 ? -19.534 -8.099  -23.225 1   37.37  ? 326 ASN B CG  1 
ATOM   3652 O  OD1 . ASN B 2 156 ? -19.082 -7.081  -22.699 1   37.49  ? 326 ASN B OD1 1 
ATOM   3653 N  ND2 . ASN B 2 156 ? -19.757 -8.142  -24.532 1   36.08  ? 326 ASN B ND2 1 
ATOM   3654 N  N   . CYS B 2 157 ? -16.901 -8.338  -20.844 1   37.02  ? 327 CYS B N   1 
ATOM   3655 C  CA  . CYS B 2 157 ? -16.212 -7.486  -19.885 1   36.14  ? 327 CYS B CA  1 
ATOM   3656 C  C   . CYS B 2 157 ? -16.782 -6.068  -19.812 1   32.17  ? 327 CYS B C   1 
ATOM   3657 O  O   . CYS B 2 157 ? -16.741 -5.438  -18.761 1   31.31  ? 327 CYS B O   1 
ATOM   3658 C  CB  . CYS B 2 157 ? -14.706 -7.481  -20.169 1   40.94  ? 327 CYS B CB  1 
ATOM   3659 S  SG  . CYS B 2 157 ? -14.238 -6.792  -21.792 1   46.92  ? 327 CYS B SG  1 
ATOM   3660 N  N   . LYS B 2 158 ? -17.334 -5.567  -20.921 1   32.9   ? 328 LYS B N   1 
ATOM   3661 C  CA  . LYS B 2 158 ? -18.002 -4.274  -20.92  1   32.34  ? 328 LYS B CA  1 
ATOM   3662 C  C   . LYS B 2 158 ? -19.283 -4.316  -20.091 1   30.16  ? 328 LYS B C   1 
ATOM   3663 O  O   . LYS B 2 158 ? -19.573 -3.379  -19.357 1   31.6   ? 328 LYS B O   1 
ATOM   3664 C  CB  . LYS B 2 158 ? -18.312 -3.806  -22.348 1   34.43  ? 328 LYS B CB  1 
ATOM   3665 C  CG  . LYS B 2 158 ? -17.097 -3.451  -23.138 1   38.38  ? 328 LYS B CG  1 
ATOM   3666 C  CD  . LYS B 2 158 ? -17.38  -3.373  -24.608 1   45.75  ? 328 LYS B CD  1 
ATOM   3667 C  CE  . LYS B 2 158 ? -18.394 -2.317  -24.974 1   50.67  ? 328 LYS B CE  1 
ATOM   3668 N  NZ  . LYS B 2 158 ? -18.644 -2.28   -26.446 1   51.05  ? 328 LYS B NZ  1 
ATOM   3669 N  N   . VAL B 2 159 ? -20.03  -5.419  -20.198 1   30.22  ? 329 VAL B N   1 
ATOM   3670 C  CA  . VAL B 2 159 ? -21.203 -5.643  -19.367 1   30.38  ? 329 VAL B CA  1 
ATOM   3671 C  C   . VAL B 2 159 ? -20.806 -5.659  -17.893 1   28.13  ? 329 VAL B C   1 
ATOM   3672 O  O   . VAL B 2 159 ? -21.463 -5.039  -17.067 1   27.93  ? 329 VAL B O   1 
ATOM   3673 C  CB  . VAL B 2 159 ? -21.948 -6.95   -19.775 1   28.96  ? 329 VAL B CB  1 
ATOM   3674 C  CG1 . VAL B 2 159 ? -22.978 -7.367  -18.728 1   29.74  ? 329 VAL B CG1 1 
ATOM   3675 C  CG2 . VAL B 2 159 ? -22.591 -6.814  -21.146 1   29.34  ? 329 VAL B CG2 1 
ATOM   3676 N  N   . GLU B 2 160 ? -19.718 -6.362  -17.565 1   30.82  ? 330 GLU B N   1 
ATOM   3677 C  CA  . GLU B 2 160 ? -19.285 -6.461  -16.182 1   31.49  ? 330 GLU B CA  1 
ATOM   3678 C  C   . GLU B 2 160 ? -18.865 -5.106  -15.632 1   31.38  ? 330 GLU B C   1 
ATOM   3679 O  O   . GLU B 2 160 ? -19.378 -4.681  -14.604 1   33     ? 330 GLU B O   1 
ATOM   3680 C  CB  . GLU B 2 160 ? -18.148 -7.458  -16.03  1   33.27  ? 330 GLU B CB  1 
ATOM   3681 C  CG  . GLU B 2 160 ? -18.628 -8.87   -16.231 1   35.29  ? 330 GLU B CG  1 
ATOM   3682 C  CD  . GLU B 2 160 ? -17.575 -9.952  -16.148 1   34.71  ? 330 GLU B CD  1 
ATOM   3683 O  OE1 . GLU B 2 160 ? -16.451 -9.665  -15.683 1   43.32  ? 330 GLU B OE1 1 
ATOM   3684 O  OE2 . GLU B 2 160 ? -17.87  -11.087 -16.581 1   34.98  ? 330 GLU B OE2 1 
ATOM   3685 N  N   . SER B 2 161 ? -17.951 -4.427  -16.334 1   31.97  ? 331 SER B N   1 
ATOM   3686 C  CA  . SER B 2 161 ? -17.514 -3.102  -15.915 1   29.68  ? 331 SER B CA  1 
ATOM   3687 C  C   . SER B 2 161 ? -18.658 -2.087  -15.853 1   30.06  ? 331 SER B C   1 
ATOM   3688 O  O   . SER B 2 161 ? -18.708 -1.27   -14.932 1   27.04  ? 331 SER B O   1 
ATOM   3689 C  CB  . SER B 2 161 ? -16.408 -2.592  -16.821 1   28.43  ? 331 SER B CB  1 
ATOM   3690 O  OG  . SER B 2 161 ? -15.197 -3.297  -16.617 1   27.71  ? 331 SER B OG  1 
ATOM   3691 N  N   . LEU B 2 162 ? -19.582 -2.137  -16.825 1   29.69  ? 332 LEU B N   1 
ATOM   3692 C  CA  . LEU B 2 162 ? -20.666 -1.168  -16.856 1   30.17  ? 332 LEU B CA  1 
ATOM   3693 C  C   . LEU B 2 162 ? -21.57  -1.37   -15.643 1   30.83  ? 332 LEU B C   1 
ATOM   3694 O  O   . LEU B 2 162 ? -21.968 -0.401  -15.011 1   30.11  ? 332 LEU B O   1 
ATOM   3695 C  CB  . LEU B 2 162 ? -21.467 -1.241  -18.163 1   30.24  ? 332 LEU B CB  1 
ATOM   3696 C  CG  . LEU B 2 162 ? -22.631 -0.259  -18.281 1   30.1   ? 332 LEU B CG  1 
ATOM   3697 C  CD1 . LEU B 2 162 ? -22.174 1.146   -18.045 1   29.9   ? 332 LEU B CD1 1 
ATOM   3698 C  CD2 . LEU B 2 162 ? -23.297 -0.343  -19.647 1   28.58  ? 332 LEU B CD2 1 
ATOM   3699 N  N   . ALA B 2 163 ? -21.848 -2.633  -15.298 1   32.9   ? 333 ALA B N   1 
ATOM   3700 C  CA  . ALA B 2 163 ? -22.627 -2.949  -14.108 1   33.24  ? 333 ALA B CA  1 
ATOM   3701 C  C   . ALA B 2 163 ? -21.971 -2.464  -12.814 1   33.12  ? 333 ALA B C   1 
ATOM   3702 O  O   . ALA B 2 163 ? -22.665 -1.985  -11.922 1   31.5   ? 333 ALA B O   1 
ATOM   3703 C  CB  . ALA B 2 163 ? -22.88  -4.441  -14.027 1   32.35  ? 333 ALA B CB  1 
ATOM   3704 N  N   . MET B 2 164 ? -20.641 -2.613  -12.713 1   34.25  ? 334 MET B N   1 
ATOM   3705 C  CA  . MET B 2 164 ? -19.883 -2.139  -11.562 1   34.47  ? 334 MET B CA  1 
ATOM   3706 C  C   . MET B 2 164 ? -20.02  -0.621  -11.442 1   31.65  ? 334 MET B C   1 
ATOM   3707 O  O   . MET B 2 164 ? -20.242 -0.089  -10.356 1   32.53  ? 334 MET B O   1 
ATOM   3708 C  CB  . MET B 2 164 ? -18.382 -2.506  -11.692 1   39.45  ? 334 MET B CB  1 
ATOM   3709 C  CG  . MET B 2 164 ? -18.071 -3.966  -11.479 1   44.67  ? 334 MET B CG  1 
ATOM   3710 S  SD  . MET B 2 164 ? -18.317 -4.396  -9.757  1   50.92  ? 334 MET B SD  1 
ATOM   3711 C  CE  . MET B 2 164 ? -17.779 -6.031  -9.759  1   60.02  ? 334 MET B CE  1 
ATOM   3712 N  N   . PHE B 2 165 ? -19.873 0.056   -12.585 1   31.21  ? 335 PHE B N   1 
ATOM   3713 C  CA  . PHE B 2 165 ? -19.982 1.5     -12.678 1   30.72  ? 335 PHE B CA  1 
ATOM   3714 C  C   . PHE B 2 165 ? -21.313 2.013   -12.141 1   29.54  ? 335 PHE B C   1 
ATOM   3715 O  O   . PHE B 2 165 ? -21.347 2.93    -11.33  1   30.01  ? 335 PHE B O   1 
ATOM   3716 C  CB  . PHE B 2 165 ? -19.827 1.912   -14.133 1   32.07  ? 335 PHE B CB  1 
ATOM   3717 C  CG  . PHE B 2 165 ? -20.123 3.353   -14.463 1   33.55  ? 335 PHE B CG  1 
ATOM   3718 C  CD1 . PHE B 2 165 ? -19.387 4.374   -13.893 1   32.58  ? 335 PHE B CD1 1 
ATOM   3719 C  CD2 . PHE B 2 165 ? -21.113 3.681   -15.371 1   33.15  ? 335 PHE B CD2 1 
ATOM   3720 C  CE1 . PHE B 2 165 ? -19.635 5.702   -14.232 1   34.13  ? 335 PHE B CE1 1 
ATOM   3721 C  CE2 . PHE B 2 165 ? -21.36  5.007   -15.711 1   35.34  ? 335 PHE B CE2 1 
ATOM   3722 C  CZ  . PHE B 2 165 ? -20.625 6.011   -15.135 1   35.43  ? 335 PHE B CZ  1 
ATOM   3723 N  N   . LEU B 2 166 ? -22.403 1.405   -12.613 1   30.32  ? 336 LEU B N   1 
ATOM   3724 C  CA  . LEU B 2 166 ? -23.746 1.81    -12.244 1   28.46  ? 336 LEU B CA  1 
ATOM   3725 C  C   . LEU B 2 166 ? -23.993 1.546   -10.763 1   32.01  ? 336 LEU B C   1 
ATOM   3726 O  O   . LEU B 2 166 ? -24.59  2.373   -10.076 1   29.44  ? 336 LEU B O   1 
ATOM   3727 C  CB  . LEU B 2 166 ? -24.763 1.051   -13.099 1   28.45  ? 336 LEU B CB  1 
ATOM   3728 C  CG  . LEU B 2 166 ? -24.738 1.362   -14.588 1   28     ? 336 LEU B CG  1 
ATOM   3729 C  CD1 . LEU B 2 166 ? -25.71  0.474   -15.331 1   28.49  ? 336 LEU B CD1 1 
ATOM   3730 C  CD2 . LEU B 2 166 ? -25.052 2.839   -14.866 1   27.69  ? 336 LEU B CD2 1 
ATOM   3731 N  N   . GLY B 2 167 ? -23.507 0.395   -10.281 1   30.94  ? 337 GLY B N   1 
ATOM   3732 C  CA  . GLY B 2 167 ? -23.569 0.072   -8.866  1   31.05  ? 337 GLY B CA  1 
ATOM   3733 C  C   . GLY B 2 167 ? -22.857 1.106   -7.998  1   32.65  ? 337 GLY B C   1 
ATOM   3734 O  O   . GLY B 2 167 ? -23.365 1.462   -6.939  1   36.29  ? 337 GLY B O   1 
ATOM   3735 N  N   . GLU B 2 168 ? -21.687 1.584   -8.45   1   32.43  ? 338 GLU B N   1 
ATOM   3736 C  CA  . GLU B 2 168 ? -20.953 2.61    -7.719  1   35.04  ? 338 GLU B CA  1 
ATOM   3737 C  C   . GLU B 2 168 ? -21.669 3.959   -7.716  1   34.35  ? 338 GLU B C   1 
ATOM   3738 O  O   . GLU B 2 168 ? -21.642 4.657   -6.709  1   36.05  ? 338 GLU B O   1 
ATOM   3739 C  CB  . GLU B 2 168 ? -19.524 2.808   -8.262  1   33.17  ? 338 GLU B CB  1 
ATOM   3740 C  CG  . GLU B 2 168 ? -18.531 1.849   -7.672  1   33.12  ? 338 GLU B CG  1 
ATOM   3741 C  CD  . GLU B 2 168 ? -17.085 2.139   -8.009  1   32.26  ? 338 GLU B CD  1 
ATOM   3742 O  OE1 . GLU B 2 168 ? -16.669 3.318   -7.955  1   30.54  ? 338 GLU B OE1 1 
ATOM   3743 O  OE2 . GLU B 2 168 ? -16.355 1.171   -8.306  1   27.56  ? 338 GLU B OE2 1 
ATOM   3744 N  N   . LEU B 2 169 ? -22.303 4.326   -8.837  1   33.21  ? 339 LEU B N   1 
ATOM   3745 C  CA  . LEU B 2 169 ? -23.066 5.566   -8.9    1   33.33  ? 339 LEU B CA  1 
ATOM   3746 C  C   . LEU B 2 169 ? -24.131 5.617   -7.804  1   31.4   ? 339 LEU B C   1 
ATOM   3747 O  O   . LEU B 2 169 ? -24.369 6.673   -7.228  1   30.76  ? 339 LEU B O   1 
ATOM   3748 C  CB  . LEU B 2 169 ? -23.744 5.757   -10.281 1   33.86  ? 339 LEU B CB  1 
ATOM   3749 C  CG  . LEU B 2 169 ? -22.818 6.034   -11.484 1   33.5   ? 339 LEU B CG  1 
ATOM   3750 C  CD1 . LEU B 2 169 ? -23.6   6.278   -12.734 1   35.12  ? 339 LEU B CD1 1 
ATOM   3751 C  CD2 . LEU B 2 169 ? -21.915 7.224   -11.239 1   35.66  ? 339 LEU B CD2 1 
ATOM   3752 N  N   . SER B 2 170 ? -24.755 4.469   -7.513  1   30.59  ? 340 SER B N   1 
ATOM   3753 C  CA  . SER B 2 170 ? -25.807 4.38    -6.512  1   31.13  ? 340 SER B CA  1 
ATOM   3754 C  C   . SER B 2 170 ? -25.313 4.669   -5.093  1   31.67  ? 340 SER B C   1 
ATOM   3755 O  O   . SER B 2 170 ? -26.082 5.111   -4.245  1   33.43  ? 340 SER B O   1 
ATOM   3756 C  CB  . SER B 2 170 ? -26.478 3.002   -6.546  1   31.91  ? 340 SER B CB  1 
ATOM   3757 O  OG  . SER B 2 170 ? -25.733 1.998   -5.866  1   29.89  ? 340 SER B OG  1 
ATOM   3758 N  N   . LEU B 2 171 ? -24.028 4.417   -4.833  1   31.33  ? 341 LEU B N   1 
ATOM   3759 C  CA  . LEU B 2 171 ? -23.434 4.762   -3.553  1   32.77  ? 341 LEU B CA  1 
ATOM   3760 C  C   . LEU B 2 171 ? -23.526 6.256   -3.231  1   34.1   ? 341 LEU B C   1 
ATOM   3761 O  O   . LEU B 2 171 ? -23.584 6.63    -2.065  1   32.01  ? 341 LEU B O   1 
ATOM   3762 C  CB  . LEU B 2 171 ? -21.957 4.355   -3.55   1   34.47  ? 341 LEU B CB  1 
ATOM   3763 C  CG  . LEU B 2 171 ? -21.636 2.871   -3.697  1   31.97  ? 341 LEU B CG  1 
ATOM   3764 C  CD1 . LEU B 2 171 ? -20.175 2.678   -3.724  1   34.01  ? 341 LEU B CD1 1 
ATOM   3765 C  CD2 . LEU B 2 171 ? -22.224 2.031   -2.569  1   30.11  ? 341 LEU B CD2 1 
ATOM   3766 N  N   . ILE B 2 172 ? -23.55  7.108   -4.264  1   31.99  ? 342 ILE B N   1 
ATOM   3767 C  CA  . ILE B 2 172 ? -23.457 8.548   -4.085  1   32.8   ? 342 ILE B CA  1 
ATOM   3768 C  C   . ILE B 2 172 ? -24.739 9.165   -3.525  1   34.38  ? 342 ILE B C   1 
ATOM   3769 O  O   . ILE B 2 172 ? -24.682 10.087  -2.707  1   32.94  ? 342 ILE B O   1 
ATOM   3770 C  CB  . ILE B 2 172 ? -23.068 9.231   -5.426  1   32.28  ? 342 ILE B CB  1 
ATOM   3771 C  CG1 . ILE B 2 172 ? -21.717 8.72    -5.966  1   33.17  ? 342 ILE B CG1 1 
ATOM   3772 C  CG2 . ILE B 2 172 ? -23.049 10.748  -5.289  1   32.77  ? 342 ILE B CG2 1 
ATOM   3773 C  CD1 . ILE B 2 172 ? -20.504 9.242   -5.225  1   33.97  ? 342 ILE B CD1 1 
ATOM   3774 N  N   . ASP B 2 173 ? -25.886 8.65    -3.982  1   33.3   ? 343 ASP B N   1 
ATOM   3775 C  CA  . ASP B 2 173 ? -27.174 9.281   -3.756  1   32.94  ? 343 ASP B CA  1 
ATOM   3776 C  C   . ASP B 2 173 ? -28.028 8.45    -2.804  1   34.17  ? 343 ASP B C   1 
ATOM   3777 O  O   . ASP B 2 173 ? -28.687 7.503   -3.23   1   35.22  ? 343 ASP B O   1 
ATOM   3778 C  CB  . ASP B 2 173 ? -27.874 9.494   -5.103  1   33.56  ? 343 ASP B CB  1 
ATOM   3779 C  CG  . ASP B 2 173 ? -27.04  10.348  -6.046  1   35.53  ? 343 ASP B CG  1 
ATOM   3780 O  OD1 . ASP B 2 173 ? -26.634 11.454  -5.636  1   41.23  ? 343 ASP B OD1 1 
ATOM   3781 O  OD2 . ASP B 2 173 ? -26.789 9.907   -7.187  1   29.42  ? 343 ASP B OD2 1 
ATOM   3782 N  N   . ALA B 2 174 ? -28.021 8.835   -1.518  1   36.11  ? 344 ALA B N   1 
ATOM   3783 C  CA  . ALA B 2 174 ? -28.796 8.166   -0.484  1   36.87  ? 344 ALA B CA  1 
ATOM   3784 C  C   . ALA B 2 174 ? -30.285 8.179   -0.804  1   33.64  ? 344 ALA B C   1 
ATOM   3785 O  O   . ALA B 2 174 ? -31.001 7.225   -0.513  1   35.84  ? 344 ALA B O   1 
ATOM   3786 C  CB  . ALA B 2 174 ? -28.56  8.832   0.857   1   42.41  ? 344 ALA B CB  1 
ATOM   3787 N  N   . ASP B 2 175 ? -30.742 9.288   -1.376  1   31.9   ? 345 ASP B N   1 
ATOM   3788 C  CA  . ASP B 2 175 ? -32.057 9.351   -1.981  1   33.69  ? 345 ASP B CA  1 
ATOM   3789 C  C   . ASP B 2 175 ? -31.879 9.231   -3.494  1   32.38  ? 345 ASP B C   1 
ATOM   3790 O  O   . ASP B 2 175 ? -31.361 10.154  -4.107  1   29.37  ? 345 ASP B O   1 
ATOM   3791 C  CB  . ASP B 2 175 ? -32.743 10.675  -1.605  1   34.74  ? 345 ASP B CB  1 
ATOM   3792 C  CG  . ASP B 2 175 ? -34.083 10.929  -2.267  1   35.11  ? 345 ASP B CG  1 
ATOM   3793 O  OD1 . ASP B 2 175 ? -34.535 10.071  -3.009  1   37.79  ? 345 ASP B OD1 1 
ATOM   3794 O  OD2 . ASP B 2 175 ? -34.665 12.003  -2.036  1   39.94  ? 345 ASP B OD2 1 
ATOM   3795 N  N   . PRO B 2 176 ? -32.355 8.154   -4.163  1   34     ? 346 PRO B N   1 
ATOM   3796 C  CA  . PRO B 2 176 ? -33.217 7.131   -3.547  1   32.89  ? 346 PRO B CA  1 
ATOM   3797 C  C   . PRO B 2 176 ? -32.604 5.81    -3.078  1   30.49  ? 346 PRO B C   1 
ATOM   3798 O  O   . PRO B 2 176 ? -33.321 4.954   -2.575  1   33.09  ? 346 PRO B O   1 
ATOM   3799 C  CB  . PRO B 2 176 ? -34.171 6.809   -4.703  1   33.33  ? 346 PRO B CB  1 
ATOM   3800 C  CG  . PRO B 2 176 ? -33.274 6.92    -5.959  1   34.25  ? 346 PRO B CG  1 
ATOM   3801 C  CD  . PRO B 2 176 ? -32.151 7.916   -5.604  1   32.79  ? 346 PRO B CD  1 
ATOM   3802 N  N   . TYR B 2 177 ? -31.29  5.609   -3.227  1   30.53  ? 347 TYR B N   1 
ATOM   3803 C  CA  . TYR B 2 177 ? -30.773 4.245   -3.193  1   30.56  ? 347 TYR B CA  1 
ATOM   3804 C  C   . TYR B 2 177 ? -30.717 3.585   -1.813  1   31.66  ? 347 TYR B C   1 
ATOM   3805 O  O   . TYR B 2 177 ? -30.626 2.364   -1.733  1   33.61  ? 347 TYR B O   1 
ATOM   3806 C  CB  . TYR B 2 177 ? -29.426 4.167   -3.947  1   30.19  ? 347 TYR B CB  1 
ATOM   3807 C  CG  . TYR B 2 177 ? -29.649 4.446   -5.418  1   30.61  ? 347 TYR B CG  1 
ATOM   3808 C  CD1 . TYR B 2 177 ? -30.364 3.558   -6.214  1   32.68  ? 347 TYR B CD1 1 
ATOM   3809 C  CD2 . TYR B 2 177 ? -29.219 5.632   -5.993  1   29.19  ? 347 TYR B CD2 1 
ATOM   3810 C  CE1 . TYR B 2 177 ? -30.619 3.833   -7.556  1   32.74  ? 347 TYR B CE1 1 
ATOM   3811 C  CE2 . TYR B 2 177 ? -29.471 5.919   -7.327  1   31.91  ? 347 TYR B CE2 1 
ATOM   3812 C  CZ  . TYR B 2 177 ? -30.169 5.017   -8.107  1   32.1   ? 347 TYR B CZ  1 
ATOM   3813 O  OH  . TYR B 2 177 ? -30.421 5.315   -9.416  1   34.52  ? 347 TYR B OH  1 
ATOM   3814 N  N   . LEU B 2 178 ? -30.844 4.363   -0.731  1   33.73  ? 348 LEU B N   1 
ATOM   3815 C  CA  . LEU B 2 178 ? -30.957 3.776   0.598   1   35.62  ? 348 LEU B CA  1 
ATOM   3816 C  C   . LEU B 2 178 ? -32.188 2.883   0.748   1   33.92  ? 348 LEU B C   1 
ATOM   3817 O  O   . LEU B 2 178 ? -32.201 1.997   1.592   1   34.2   ? 348 LEU B O   1 
ATOM   3818 C  CB  . LEU B 2 178 ? -31.002 4.844   1.702   1   36.96  ? 348 LEU B CB  1 
ATOM   3819 C  CG  . LEU B 2 178 ? -29.675 5.449   2.12    1   42.22  ? 348 LEU B CG  1 
ATOM   3820 C  CD1 . LEU B 2 178 ? -29.864 6.366   3.334   1   41.64  ? 348 LEU B CD1 1 
ATOM   3821 C  CD2 . LEU B 2 178 ? -28.616 4.372   2.42    1   45.27  ? 348 LEU B CD2 1 
ATOM   3822 N  N   . LYS B 2 179 ? -33.225 3.102   -0.066  1   35.82  ? 349 LYS B N   1 
ATOM   3823 C  CA  . LYS B 2 179 ? -34.407 2.264   0.032   1   37.92  ? 349 LYS B CA  1 
ATOM   3824 C  C   . LYS B 2 179 ? -34.238 0.884   -0.606  1   36.49  ? 349 LYS B C   1 
ATOM   3825 O  O   . LYS B 2 179 ? -35.084 0.024   -0.401  1   36.1   ? 349 LYS B O   1 
ATOM   3826 C  CB  . LYS B 2 179 ? -35.623 2.986   -0.557  1   42.61  ? 349 LYS B CB  1 
ATOM   3827 C  CG  . LYS B 2 179 ? -35.725 2.97    -2.064  1   48.78  ? 349 LYS B CG  1 
ATOM   3828 C  CD  . LYS B 2 179 ? -36.947 3.776   -2.59   1   53.55  ? 349 LYS B CD  1 
ATOM   3829 C  CE  . LYS B 2 179 ? -36.856 5.245   -2.292  1   52.55  ? 349 LYS B CE  1 
ATOM   3830 N  NZ  . LYS B 2 179 ? -37.819 6.004   -3.115  1   58.21  ? 349 LYS B NZ  1 
ATOM   3831 N  N   . TYR B 2 180 ? -33.159 0.671   -1.372  1   33.55  ? 350 TYR B N   1 
ATOM   3832 C  CA  . TYR B 2 180 ? -32.948 -0.599  -2.047  1   34.81  ? 350 TYR B CA  1 
ATOM   3833 C  C   . TYR B 2 180 ? -31.803 -1.397  -1.424  1   35.28  ? 350 TYR B C   1 
ATOM   3834 O  O   . TYR B 2 180 ? -30.764 -0.839  -1.066  1   31.3   ? 350 TYR B O   1 
ATOM   3835 C  CB  . TYR B 2 180 ? -32.653 -0.371  -3.543  1   33.98  ? 350 TYR B CB  1 
ATOM   3836 C  CG  . TYR B 2 180 ? -33.717 0.408   -4.283  1   30.69  ? 350 TYR B CG  1 
ATOM   3837 C  CD1 . TYR B 2 180 ? -34.994 -0.107  -4.45   1   29.47  ? 350 TYR B CD1 1 
ATOM   3838 C  CD2 . TYR B 2 180 ? -33.44  1.662   -4.827  1   29.69  ? 350 TYR B CD2 1 
ATOM   3839 C  CE1 . TYR B 2 180 ? -35.974 0.599   -5.148  1   28.63  ? 350 TYR B CE1 1 
ATOM   3840 C  CE2 . TYR B 2 180 ? -34.41  2.38    -5.52   1   29.66  ? 350 TYR B CE2 1 
ATOM   3841 C  CZ  . TYR B 2 180 ? -35.679 1.847   -5.678  1   30.54  ? 350 TYR B CZ  1 
ATOM   3842 O  OH  . TYR B 2 180 ? -36.637 2.552   -6.368  1   28.89  ? 350 TYR B OH  1 
ATOM   3843 N  N   . LEU B 2 181 ? -32.006 -2.716  -1.325  1   39.61  ? 351 LEU B N   1 
ATOM   3844 C  CA  . LEU B 2 181 ? -30.997 -3.646  -0.837  1   37.39  ? 351 LEU B CA  1 
ATOM   3845 C  C   . LEU B 2 181 ? -29.91  -3.868  -1.884  1   34.94  ? 351 LEU B C   1 
ATOM   3846 O  O   . LEU B 2 181 ? -30.165 -3.807  -3.084  1   31.17  ? 351 LEU B O   1 
ATOM   3847 C  CB  . LEU B 2 181 ? -31.65  -5.014  -0.519  1   41.89  ? 351 LEU B CB  1 
ATOM   3848 C  CG  . LEU B 2 181 ? -32.629 -5.047  0.655   1   41.81  ? 351 LEU B CG  1 
ATOM   3849 C  CD1 . LEU B 2 181 ? -33.394 -6.343  0.69    1   41.24  ? 351 LEU B CD1 1 
ATOM   3850 C  CD2 . LEU B 2 181 ? -31.902 -4.856  1.958   1   42.22  ? 351 LEU B CD2 1 
ATOM   3851 N  N   . PRO B 2 182 ? -28.667 -4.173  -1.463  1   35.55  ? 352 PRO B N   1 
ATOM   3852 C  CA  . PRO B 2 182 ? -27.583 -4.437  -2.408  1   33.84  ? 352 PRO B CA  1 
ATOM   3853 C  C   . PRO B 2 182 ? -27.934 -5.394  -3.547  1   32.95  ? 352 PRO B C   1 
ATOM   3854 O  O   . PRO B 2 182 ? -27.568 -5.151  -4.696  1   32.48  ? 352 PRO B O   1 
ATOM   3855 C  CB  . PRO B 2 182 ? -26.498 -5.025  -1.509  1   35.27  ? 352 PRO B CB  1 
ATOM   3856 C  CG  . PRO B 2 182 ? -26.752 -4.428  -0.149  1   37.41  ? 352 PRO B CG  1 
ATOM   3857 C  CD  . PRO B 2 182 ? -28.242 -4.247  -0.054  1   35.76  ? 352 PRO B CD  1 
ATOM   3858 N  N   . SER B 2 183 ? -28.646 -6.477  -3.218  1   31.97  ? 353 SER B N   1 
ATOM   3859 C  CA  . SER B 2 183 ? -28.955 -7.51   -4.193  1   30.21  ? 353 SER B CA  1 
ATOM   3860 C  C   . SER B 2 183 ? -29.901 -7.013  -5.281  1   31.38  ? 353 SER B C   1 
ATOM   3861 O  O   . SER B 2 183 ? -29.847 -7.506  -6.408  1   35.47  ? 353 SER B O   1 
ATOM   3862 C  CB  . SER B 2 183 ? -29.55  -8.742  -3.503  1   30.49  ? 353 SER B CB  1 
ATOM   3863 O  OG  . SER B 2 183 ? -30.854 -8.522  -2.978  1   27.31  ? 353 SER B OG  1 
ATOM   3864 N  N   . VAL B 2 184 ? -30.77  -6.053  -4.923  1   29.89  ? 354 VAL B N   1 
ATOM   3865 C  CA  . VAL B 2 184 ? -31.675 -5.426  -5.872  1   30     ? 354 VAL B CA  1 
ATOM   3866 C  C   . VAL B 2 184 ? -30.968 -4.401  -6.758  1   31.72  ? 354 VAL B C   1 
ATOM   3867 O  O   . VAL B 2 184 ? -31.185 -4.387  -7.969  1   31.65  ? 354 VAL B O   1 
ATOM   3868 C  CB  . VAL B 2 184 ? -32.901 -4.809  -5.16   1   33.34  ? 354 VAL B CB  1 
ATOM   3869 C  CG1 . VAL B 2 184 ? -33.712 -3.913  -6.102  1   33.15  ? 354 VAL B CG1 1 
ATOM   3870 C  CG2 . VAL B 2 184 ? -33.79  -5.907  -4.561  1   33.91  ? 354 VAL B CG2 1 
ATOM   3871 N  N   . ILE B 2 185 ? -30.143 -3.53   -6.166  1   31.79  ? 355 ILE B N   1 
ATOM   3872 C  CA  . ILE B 2 185 ? -29.369 -2.586  -6.956  1   32.4   ? 355 ILE B CA  1 
ATOM   3873 C  C   . ILE B 2 185 ? -28.48  -3.345  -7.939  1   33.77  ? 355 ILE B C   1 
ATOM   3874 O  O   . ILE B 2 185 ? -28.35  -2.953  -9.097  1   30.24  ? 355 ILE B O   1 
ATOM   3875 C  CB  . ILE B 2 185 ? -28.543 -1.626  -6.085  1   35.69  ? 355 ILE B CB  1 
ATOM   3876 C  CG1 . ILE B 2 185 ? -29.458 -0.693  -5.279  1   37.06  ? 355 ILE B CG1 1 
ATOM   3877 C  CG2 . ILE B 2 185 ? -27.555 -0.815  -6.925  1   33.42  ? 355 ILE B CG2 1 
ATOM   3878 C  CD1 . ILE B 2 185 ? -28.726 0.095   -4.205  1   33.48  ? 355 ILE B CD1 1 
ATOM   3879 N  N   . ALA B 2 186 ? -27.871 -4.437  -7.463  1   35.98  ? 356 ALA B N   1 
ATOM   3880 C  CA  . ALA B 2 186 ? -26.993 -5.244  -8.295  1   33.47  ? 356 ALA B CA  1 
ATOM   3881 C  C   . ALA B 2 186 ? -27.752 -5.825  -9.486  1   30.86  ? 356 ALA B C   1 
ATOM   3882 O  O   . ALA B 2 186 ? -27.25  -5.829  -10.606 1   35.63  ? 356 ALA B O   1 
ATOM   3883 C  CB  . ALA B 2 186 ? -26.369 -6.359  -7.478  1   33.38  ? 356 ALA B CB  1 
ATOM   3884 N  N   . ALA B 2 187 ? -28.967 -6.308  -9.23   1   29.91  ? 357 ALA B N   1 
ATOM   3885 C  CA  . ALA B 2 187 ? -29.813 -6.859  -10.274 1   28.43  ? 357 ALA B CA  1 
ATOM   3886 C  C   . ALA B 2 187 ? -30.147 -5.787  -11.303 1   27.71  ? 357 ALA B C   1 
ATOM   3887 O  O   . ALA B 2 187 ? -30.018 -6.016  -12.503 1   28.93  ? 357 ALA B O   1 
ATOM   3888 C  CB  . ALA B 2 187 ? -31.077 -7.445  -9.676  1   30.5   ? 357 ALA B CB  1 
ATOM   3889 N  N   . ALA B 2 188 ? -30.568 -4.611  -10.826 1   30.18  ? 358 ALA B N   1 
ATOM   3890 C  CA  . ALA B 2 188 ? -30.924 -3.514  -11.716 1   31.32  ? 358 ALA B CA  1 
ATOM   3891 C  C   . ALA B 2 188 ? -29.726 -3.114  -12.567 1   30.28  ? 358 ALA B C   1 
ATOM   3892 O  O   . ALA B 2 188 ? -29.842 -2.944  -13.773 1   29.82  ? 358 ALA B O   1 
ATOM   3893 C  CB  . ALA B 2 188 ? -31.43  -2.317  -10.935 1   31.47  ? 358 ALA B CB  1 
ATOM   3894 N  N   . ALA B 2 189 ? -28.571 -2.977  -11.909 1   33.79  ? 359 ALA B N   1 
ATOM   3895 C  CA  . ALA B 2 189 ? -27.329 -2.625  -12.569 1   30.42  ? 359 ALA B CA  1 
ATOM   3896 C  C   . ALA B 2 189 ? -26.948 -3.652  -13.63  1   28.43  ? 359 ALA B C   1 
ATOM   3897 O  O   . ALA B 2 189 ? -26.552 -3.291  -14.736 1   26.32  ? 359 ALA B O   1 
ATOM   3898 C  CB  . ALA B 2 189 ? -26.233 -2.495  -11.531 1   29.97  ? 359 ALA B CB  1 
ATOM   3899 N  N   . PHE B 2 190 ? -27.056 -4.936  -13.278 1   28.81  ? 360 PHE B N   1 
ATOM   3900 C  CA  . PHE B 2 190 ? -26.705 -6.001  -14.199 1   29.82  ? 360 PHE B CA  1 
ATOM   3901 C  C   . PHE B 2 190 ? -27.595 -5.977  -15.443 1   29.3   ? 360 PHE B C   1 
ATOM   3902 O  O   . PHE B 2 190 ? -27.095 -6.063  -16.564 1   29.05  ? 360 PHE B O   1 
ATOM   3903 C  CB  . PHE B 2 190 ? -26.769 -7.37   -13.501 1   30.44  ? 360 PHE B CB  1 
ATOM   3904 C  CG  . PHE B 2 190 ? -26.391 -8.506  -14.419 1   29.5   ? 360 PHE B CG  1 
ATOM   3905 C  CD1 . PHE B 2 190 ? -25.131 -8.575  -14.972 1   29.6   ? 360 PHE B CD1 1 
ATOM   3906 C  CD2 . PHE B 2 190 ? -27.315 -9.48   -14.758 1   35.7   ? 360 PHE B CD2 1 
ATOM   3907 C  CE1 . PHE B 2 190 ? -24.791 -9.6    -15.848 1   32.21  ? 360 PHE B CE1 1 
ATOM   3908 C  CE2 . PHE B 2 190 ? -26.976 -10.507 -15.632 1   38.84  ? 360 PHE B CE2 1 
ATOM   3909 C  CZ  . PHE B 2 190 ? -25.717 -10.559 -16.175 1   34.04  ? 360 PHE B CZ  1 
ATOM   3910 N  N   . HIS B 2 191 ? -28.911 -5.841  -15.234 1   28.38  ? 361 HIS B N   1 
ATOM   3911 C  CA  . HIS B 2 191 ? -29.857 -5.822  -16.336 1   27.69  ? 361 HIS B CA  1 
ATOM   3912 C  C   . HIS B 2 191 ? -29.62  -4.628  -17.253 1   27.38  ? 361 HIS B C   1 
ATOM   3913 O  O   . HIS B 2 191 ? -29.65  -4.748  -18.477 1   23.77  ? 361 HIS B O   1 
ATOM   3914 C  CB  . HIS B 2 191 ? -31.314 -5.76   -15.874 1   25.5   ? 361 HIS B CB  1 
ATOM   3915 C  CG  . HIS B 2 191 ? -32.229 -5.471  -17.022 1   25.03  ? 361 HIS B CG  1 
ATOM   3916 N  ND1 . HIS B 2 191 ? -32.512 -6.433  -17.977 1   26.47  ? 361 HIS B ND1 1 
ATOM   3917 C  CD2 . HIS B 2 191 ? -32.828 -4.308  -17.376 1   24.69  ? 361 HIS B CD2 1 
ATOM   3918 C  CE1 . HIS B 2 191 ? -33.294 -5.831  -18.872 1   26.8   ? 361 HIS B CE1 1 
ATOM   3919 N  NE2 . HIS B 2 191 ? -33.515 -4.551  -18.538 1   26.06  ? 361 HIS B NE2 1 
ATOM   3920 N  N   . LEU B 2 192 ? -29.433 -3.466  -16.63  1   27.35  ? 362 LEU B N   1 
ATOM   3921 C  CA  . LEU B 2 192 ? -29.264 -2.233  -17.369 1   28.07  ? 362 LEU B CA  1 
ATOM   3922 C  C   . LEU B 2 192 ? -27.982 -2.291  -18.198 1   30.35  ? 362 LEU B C   1 
ATOM   3923 O  O   . LEU B 2 192 ? -27.983 -1.902  -19.369 1   29.01  ? 362 LEU B O   1 
ATOM   3924 C  CB  . LEU B 2 192 ? -29.257 -1.077  -16.379 1   26.84  ? 362 LEU B CB  1 
ATOM   3925 C  CG  . LEU B 2 192 ? -29.253 0.308   -16.962 1   27.97  ? 362 LEU B CG  1 
ATOM   3926 C  CD1 . LEU B 2 192 ? -30.338 0.476   -17.983 1   27.98  ? 362 LEU B CD1 1 
ATOM   3927 C  CD2 . LEU B 2 192 ? -29.418 1.334   -15.869 1   29.98  ? 362 LEU B CD2 1 
ATOM   3928 N  N   . ALA B 2 193 ? -26.907 -2.803  -17.584 1   28.35  ? 363 ALA B N   1 
ATOM   3929 C  CA  . ALA B 2 193 ? -25.632 -2.965  -18.264 1   28.1   ? 363 ALA B CA  1 
ATOM   3930 C  C   . ALA B 2 193 ? -25.735 -3.936  -19.439 1   28.22  ? 363 ALA B C   1 
ATOM   3931 O  O   . ALA B 2 193 ? -25.273 -3.628  -20.539 1   28.56  ? 363 ALA B O   1 
ATOM   3932 C  CB  . ALA B 2 193 ? -24.582 -3.444  -17.285 1   27.46  ? 363 ALA B CB  1 
ATOM   3933 N  N   . LEU B 2 194 ? -26.336 -5.102  -19.177 1   28.6   ? 364 LEU B N   1 
ATOM   3934 C  CA  . LEU B 2 194 ? -26.577 -6.123  -20.184 1   31.63  ? 364 LEU B CA  1 
ATOM   3935 C  C   . LEU B 2 194 ? -27.383 -5.563  -21.354 1   34.59  ? 364 LEU B C   1 
ATOM   3936 O  O   . LEU B 2 194 ? -27     -5.714  -22.52  1   36.5   ? 364 LEU B O   1 
ATOM   3937 C  CB  . LEU B 2 194 ? -27.323 -7.292  -19.512 1   35.26  ? 364 LEU B CB  1 
ATOM   3938 C  CG  . LEU B 2 194 ? -27.503 -8.569  -20.307 1   40.91  ? 364 LEU B CG  1 
ATOM   3939 C  CD1 . LEU B 2 194 ? -26.174 -9.273  -20.581 1   43.4   ? 364 LEU B CD1 1 
ATOM   3940 C  CD2 . LEU B 2 194 ? -28.426 -9.504  -19.603 1   46.06  ? 364 LEU B CD2 1 
ATOM   3941 N  N   . TYR B 2 195 ? -28.49  -4.886  -21.023 1   32.43  ? 365 TYR B N   1 
ATOM   3942 C  CA  . TYR B 2 195 ? -29.351 -4.292  -22.028 1   30.33  ? 365 TYR B CA  1 
ATOM   3943 C  C   . TYR B 2 195 ? -28.613 -3.234  -22.852 1   27.76  ? 365 TYR B C   1 
ATOM   3944 O  O   . TYR B 2 195 ? -28.742 -3.212  -24.066 1   25.33  ? 365 TYR B O   1 
ATOM   3945 C  CB  . TYR B 2 195 ? -30.617 -3.718  -21.372 1   31.56  ? 365 TYR B CB  1 
ATOM   3946 C  CG  . TYR B 2 195 ? -31.611 -3.159  -22.366 1   32.16  ? 365 TYR B CG  1 
ATOM   3947 C  CD1 . TYR B 2 195 ? -32.385 -4      -23.158 1   36.37  ? 365 TYR B CD1 1 
ATOM   3948 C  CD2 . TYR B 2 195 ? -31.741 -1.794  -22.552 1   31.9   ? 365 TYR B CD2 1 
ATOM   3949 C  CE1 . TYR B 2 195 ? -33.283 -3.49   -24.093 1   37.36  ? 365 TYR B CE1 1 
ATOM   3950 C  CE2 . TYR B 2 195 ? -32.645 -1.272  -23.469 1   35.74  ? 365 TYR B CE2 1 
ATOM   3951 C  CZ  . TYR B 2 195 ? -33.408 -2.123  -24.246 1   37.77  ? 365 TYR B CZ  1 
ATOM   3952 O  OH  . TYR B 2 195 ? -34.299 -1.599  -25.153 1   49.12  ? 365 TYR B OH  1 
ATOM   3953 N  N   . THR B 2 196 ? -27.828 -2.378  -22.189 1   27.2   ? 366 THR B N   1 
ATOM   3954 C  CA  . THR B 2 196 ? -27.117 -1.304  -22.863 1   27.25  ? 366 THR B CA  1 
ATOM   3955 C  C   . THR B 2 196 ? -26.071 -1.821  -23.848 1   27.44  ? 366 THR B C   1 
ATOM   3956 O  O   . THR B 2 196 ? -25.949 -1.285  -24.942 1   29.34  ? 366 THR B O   1 
ATOM   3957 C  CB  . THR B 2 196 ? -26.436 -0.358  -21.852 1   27.87  ? 366 THR B CB  1 
ATOM   3958 O  OG1 . THR B 2 196 ? -27.425 0.208   -20.992 1   28.07  ? 366 THR B OG1 1 
ATOM   3959 C  CG2 . THR B 2 196 ? -25.659 0.762   -22.534 1   27.48  ? 366 THR B CG2 1 
ATOM   3960 N  N   . VAL B 2 197 ? -25.32  -2.853  -23.456 1   29.61  ? 367 VAL B N   1 
ATOM   3961 C  CA  . VAL B 2 197 ? -24.232 -3.354  -24.28  1   30.81  ? 367 VAL B CA  1 
ATOM   3962 C  C   . VAL B 2 197 ? -24.725 -4.32   -25.354 1   29.05  ? 367 VAL B C   1 
ATOM   3963 O  O   . VAL B 2 197 ? -24.277 -4.233  -26.492 1   28.53  ? 367 VAL B O   1 
ATOM   3964 C  CB  . VAL B 2 197 ? -23.13  -4.01   -23.409 1   33.4   ? 367 VAL B CB  1 
ATOM   3965 C  CG1 . VAL B 2 197 ? -22.01  -4.595  -24.267 1   34.06  ? 367 VAL B CG1 1 
ATOM   3966 C  CG2 . VAL B 2 197 ? -22.568 -3.019  -22.403 1   34.23  ? 367 VAL B CG2 1 
ATOM   3967 N  N   . THR B 2 198 ? -25.634 -5.237  -24.986 1   30.3   ? 368 THR B N   1 
ATOM   3968 C  CA  . THR B 2 198 ? -26.031 -6.331  -25.864 1   28.48  ? 368 THR B CA  1 
ATOM   3969 C  C   . THR B 2 198 ? -27.496 -6.383  -26.292 1   28.31  ? 368 THR B C   1 
ATOM   3970 O  O   . THR B 2 198 ? -27.866 -7.237  -27.091 1   29.43  ? 368 THR B O   1 
ATOM   3971 C  CB  . THR B 2 198 ? -25.747 -7.684  -25.178 1   29.01  ? 368 THR B CB  1 
ATOM   3972 O  OG1 . THR B 2 198 ? -26.71  -7.899  -24.134 1   28.22  ? 368 THR B OG1 1 
ATOM   3973 C  CG2 . THR B 2 198 ? -24.351 -7.77   -24.625 1   30.08  ? 368 THR B CG2 1 
ATOM   3974 N  N   . GLY B 2 199 ? -28.347 -5.534  -25.705 1   29.2   ? 369 GLY B N   1 
ATOM   3975 C  CA  . GLY B 2 199 ? -29.777 -5.604  -25.958 1   29.25  ? 369 GLY B CA  1 
ATOM   3976 C  C   . GLY B 2 199 ? -30.529 -6.704  -25.201 1   33.35  ? 369 GLY B C   1 
ATOM   3977 O  O   . GLY B 2 199 ? -31.753 -6.736  -25.223 1   33.43  ? 369 GLY B O   1 
ATOM   3978 N  N   . GLN B 2 200 ? -29.803 -7.607  -24.526 1   38.72  ? 370 GLN B N   1 
ATOM   3979 C  CA  . GLN B 2 200 ? -30.422 -8.708  -23.802 1   38.68  ? 370 GLN B CA  1 
ATOM   3980 C  C   . GLN B 2 200 ? -30.959 -8.236  -22.459 1   36.29  ? 370 GLN B C   1 
ATOM   3981 O  O   . GLN B 2 200 ? -30.647 -7.13   -22.023 1   36.45  ? 370 GLN B O   1 
ATOM   3982 C  CB  . GLN B 2 200 ? -29.431 -9.842  -23.568 1   42.7   ? 370 GLN B CB  1 
ATOM   3983 C  CG  . GLN B 2 200 ? -28.96  -10.455 -24.849 1   46.01  ? 370 GLN B CG  1 
ATOM   3984 C  CD  . GLN B 2 200 ? -27.987 -11.553 -24.58  1   53.84  ? 370 GLN B CD  1 
ATOM   3985 O  OE1 . GLN B 2 200 ? -28.235 -12.712 -24.904 1   65.71  ? 370 GLN B OE1 1 
ATOM   3986 N  NE2 . GLN B 2 200 ? -26.858 -11.21  -23.971 1   59.05  ? 370 GLN B NE2 1 
ATOM   3987 N  N   . SER B 2 201 ? -31.752 -9.099  -21.814 1   35.29  ? 371 SER B N   1 
ATOM   3988 C  CA  . SER B 2 201 ? -32.399 -8.777  -20.554 1   32.5   ? 371 SER B CA  1 
ATOM   3989 C  C   . SER B 2 201 ? -32.044 -9.748  -19.441 1   30.73  ? 371 SER B C   1 
ATOM   3990 O  O   . SER B 2 201 ? -31.514 -10.818 -19.703 1   31.14  ? 371 SER B O   1 
ATOM   3991 C  CB  . SER B 2 201 ? -33.908 -8.757  -20.723 1   31.11  ? 371 SER B CB  1 
ATOM   3992 O  OG  . SER B 2 201 ? -34.261 -7.708  -21.598 1   32.88  ? 371 SER B OG  1 
ATOM   3993 N  N   . TRP B 2 202 ? -32.341 -9.325  -18.206 1   36.4   ? 372 TRP B N   1 
ATOM   3994 C  CA  . TRP B 2 202 ? -32.269 -10.156 -17.011 1   33.99  ? 372 TRP B CA  1 
ATOM   3995 C  C   . TRP B 2 202 ? -32.636 -11.6   -17.346 1   31.22  ? 372 TRP B C   1 
ATOM   3996 O  O   . TRP B 2 202 ? -33.769 -11.872 -17.73  1   31.1   ? 372 TRP B O   1 
ATOM   3997 C  CB  . TRP B 2 202 ? -33.235 -9.572  -15.945 1   32.16  ? 372 TRP B CB  1 
ATOM   3998 C  CG  . TRP B 2 202 ? -33.257 -10.256 -14.61  1   31.83  ? 372 TRP B CG  1 
ATOM   3999 C  CD1 . TRP B 2 202 ? -34.28  -10.999 -14.083 1   33.55  ? 372 TRP B CD1 1 
ATOM   4000 C  CD2 . TRP B 2 202 ? -32.234 -10.221 -13.612 1   30.36  ? 372 TRP B CD2 1 
ATOM   4001 N  NE1 . TRP B 2 202 ? -33.944 -11.443 -12.829 1   31.67  ? 372 TRP B NE1 1 
ATOM   4002 C  CE2 . TRP B 2 202 ? -32.7   -10.967 -12.507 1   31.67  ? 372 TRP B CE2 1 
ATOM   4003 C  CE3 . TRP B 2 202 ? -30.972 -9.627  -13.539 1   31.03  ? 372 TRP B CE3 1 
ATOM   4004 C  CZ2 . TRP B 2 202 ? -31.943 -11.143 -11.353 1   32.43  ? 372 TRP B CZ2 1 
ATOM   4005 C  CZ3 . TRP B 2 202 ? -30.223 -9.803  -12.395 1   31.97  ? 372 TRP B CZ3 1 
ATOM   4006 C  CH2 . TRP B 2 202 ? -30.708 -10.555 -11.319 1   31.4   ? 372 TRP B CH2 1 
ATOM   4007 N  N   . PRO B 2 203 ? -31.692 -12.561 -17.248 1   28.19  ? 373 PRO B N   1 
ATOM   4008 C  CA  . PRO B 2 203 ? -31.95  -13.931 -17.692 1   28.48  ? 373 PRO B CA  1 
ATOM   4009 C  C   . PRO B 2 203 ? -32.814 -14.745 -16.733 1   29.01  ? 373 PRO B C   1 
ATOM   4010 O  O   . PRO B 2 203 ? -32.77  -14.556 -15.511 1   29.85  ? 373 PRO B O   1 
ATOM   4011 C  CB  . PRO B 2 203 ? -30.544 -14.528 -17.801 1   28.3   ? 373 PRO B CB  1 
ATOM   4012 C  CG  . PRO B 2 203 ? -29.741 -13.772 -16.757 1   28.56  ? 373 PRO B CG  1 
ATOM   4013 C  CD  . PRO B 2 203 ? -30.326 -12.367 -16.741 1   27.68  ? 373 PRO B CD  1 
ATOM   4014 N  N   . GLU B 2 204 ? -33.548 -15.693 -17.32  1   27.37  ? 374 GLU B N   1 
ATOM   4015 C  CA  . GLU B 2 204 ? -34.428 -16.585 -16.589 1   28.99  ? 374 GLU B CA  1 
ATOM   4016 C  C   . GLU B 2 204 ? -33.69  -17.332 -15.483 1   29.49  ? 374 GLU B C   1 
ATOM   4017 O  O   . GLU B 2 204 ? -34.259 -17.566 -14.418 1   28.14  ? 374 GLU B O   1 
ATOM   4018 C  CB  . GLU B 2 204 ? -35.087 -17.579 -17.559 1   33.39  ? 374 GLU B CB  1 
ATOM   4019 C  CG  . GLU B 2 204 ? -36.26  -18.316 -16.937 1   36.37  ? 374 GLU B CG  1 
ATOM   4020 C  CD  . GLU B 2 204 ? -35.977 -19.583 -16.149 1   37.03  ? 374 GLU B CD  1 
ATOM   4021 O  OE1 . GLU B 2 204 ? -34.807 -20.022 -16.044 1   37.47  ? 374 GLU B OE1 1 
ATOM   4022 O  OE2 . GLU B 2 204 ? -36.964 -20.138 -15.619 1   36.66  ? 374 GLU B OE2 1 
ATOM   4023 N  N   . SER B 2 205 ? -32.417 -17.679 -15.737 1   28.47  ? 375 SER B N   1 
ATOM   4024 C  CA  . SER B 2 205 ? -31.616 -18.41  -14.771 1   28.39  ? 375 SER B CA  1 
ATOM   4025 C  C   . SER B 2 205 ? -31.394 -17.63  -13.47  1   28.83  ? 375 SER B C   1 
ATOM   4026 O  O   . SER B 2 205 ? -31.237 -18.228 -12.402 1   28.47  ? 375 SER B O   1 
ATOM   4027 C  CB  . SER B 2 205 ? -30.29  -18.833 -15.395 1   29.14  ? 375 SER B CB  1 
ATOM   4028 O  OG  . SER B 2 205 ? -29.4   -17.744 -15.549 1   30.28  ? 375 SER B OG  1 
ATOM   4029 N  N   . LEU B 2 206 ? -31.376 -16.294 -13.572 1   28.34  ? 376 LEU B N   1 
ATOM   4030 C  CA  . LEU B 2 206 ? -31.239 -15.431 -12.407 1   28.44  ? 376 LEU B CA  1 
ATOM   4031 C  C   . LEU B 2 206 ? -32.58  -15.138 -11.737 1   28.68  ? 376 LEU B C   1 
ATOM   4032 O  O   . LEU B 2 206 ? -32.624 -14.805 -10.552 1   28.16  ? 376 LEU B O   1 
ATOM   4033 C  CB  . LEU B 2 206 ? -30.558 -14.122 -12.805 1   28.79  ? 376 LEU B CB  1 
ATOM   4034 C  CG  . LEU B 2 206 ? -29.054 -14.23  -12.973 1   31     ? 376 LEU B CG  1 
ATOM   4035 C  CD1 . LEU B 2 206 ? -28.436 -12.955 -13.521 1   29.74  ? 376 LEU B CD1 1 
ATOM   4036 C  CD2 . LEU B 2 206 ? -28.389 -14.599 -11.65  1   30.78  ? 376 LEU B CD2 1 
ATOM   4037 N  N   . VAL B 2 207 ? -33.666 -15.249 -12.506 1   27.58  ? 377 VAL B N   1 
ATOM   4038 C  CA  . VAL B 2 207 ? -34.996 -15.306 -11.926 1   31.93  ? 377 VAL B CA  1 
ATOM   4039 C  C   . VAL B 2 207 ? -35.069 -16.52  -10.997 1   31.15  ? 377 VAL B C   1 
ATOM   4040 O  O   . VAL B 2 207 ? -35.534 -16.397 -9.869  1   28.14  ? 377 VAL B O   1 
ATOM   4041 C  CB  . VAL B 2 207 ? -36.113 -15.342 -13.011 1   33.33  ? 377 VAL B CB  1 
ATOM   4042 C  CG1 . VAL B 2 207 ? -37.489 -15.54  -12.379 1   32.24  ? 377 VAL B CG1 1 
ATOM   4043 C  CG2 . VAL B 2 207 ? -36.082 -14.083 -13.884 1   32.95  ? 377 VAL B CG2 1 
ATOM   4044 N  N   . GLN B 2 208 ? -34.599 -17.684 -11.48  1   33.2   ? 378 GLN B N   1 
ATOM   4045 C  CA  . GLN B 2 208 ? -34.553 -18.903 -10.685 1   33.55  ? 378 GLN B CA  1 
ATOM   4046 C  C   . GLN B 2 208 ? -33.75  -18.7   -9.403  1   34.84  ? 378 GLN B C   1 
ATOM   4047 O  O   . GLN B 2 208 ? -34.177 -19.103 -8.322  1   32.53  ? 378 GLN B O   1 
ATOM   4048 C  CB  . GLN B 2 208 ? -33.886 -20.08  -11.453 1   32.3   ? 378 GLN B CB  1 
ATOM   4049 C  CG  . GLN B 2 208 ? -34.688 -20.702 -12.569 1   32.27  ? 378 GLN B CG  1 
ATOM   4050 C  CD  . GLN B 2 208 ? -35.989 -21.288 -12.075 1   35.06  ? 378 GLN B CD  1 
ATOM   4051 O  OE1 . GLN B 2 208 ? -36.082 -21.862 -10.976 1   38.26  ? 378 GLN B OE1 1 
ATOM   4052 N  NE2 . GLN B 2 208 ? -37.043 -21.168 -12.886 1   31.56  ? 378 GLN B NE2 1 
ATOM   4053 N  N   . LYS B 2 209 ? -32.564 -18.099 -9.555  1   34.42  ? 379 LYS B N   1 
ATOM   4054 C  CA  . LYS B 2 209 ? -31.637 -17.959 -8.448  1   35.97  ? 379 LYS B CA  1 
ATOM   4055 C  C   . LYS B 2 209 ? -32.134 -16.969 -7.398  1   32.97  ? 379 LYS B C   1 
ATOM   4056 O  O   . LYS B 2 209 ? -32.07  -17.259 -6.2    1   30.77  ? 379 LYS B O   1 
ATOM   4057 C  CB  . LYS B 2 209 ? -30.266 -17.519 -8.964  1   40.56  ? 379 LYS B CB  1 
ATOM   4058 C  CG  . LYS B 2 209 ? -29.171 -17.423 -7.891  1   40.76  ? 379 LYS B CG  1 
ATOM   4059 C  CD  . LYS B 2 209 ? -27.931 -16.69  -8.429  1   44.48  ? 379 LYS B CD  1 
ATOM   4060 C  CE  . LYS B 2 209 ? -26.809 -16.544 -7.427  1   46.11  ? 379 LYS B CE  1 
ATOM   4061 N  NZ  . LYS B 2 209 ? -26.152 -17.834 -7.181  1   48.76  ? 379 LYS B NZ  1 
ATOM   4062 N  N   . THR B 2 210 ? -32.616 -15.806 -7.856  1   30.21  ? 380 THR B N   1 
ATOM   4063 C  CA  . THR B 2 210 ? -32.883 -14.688 -6.961  1   30.46  ? 380 THR B CA  1 
ATOM   4064 C  C   . THR B 2 210 ? -34.344 -14.535 -6.547  1   27.41  ? 380 THR B C   1 
ATOM   4065 O  O   . THR B 2 210 ? -34.621 -13.907 -5.53   1   31.54  ? 380 THR B O   1 
ATOM   4066 C  CB  . THR B 2 210 ? -32.428 -13.355 -7.599  1   31.06  ? 380 THR B CB  1 
ATOM   4067 O  OG1 . THR B 2 210 ? -33.288 -13.013 -8.706  1   27.72  ? 380 THR B OG1 1 
ATOM   4068 C  CG2 . THR B 2 210 ? -30.98  -13.404 -8.074  1   32.03  ? 380 THR B CG2 1 
ATOM   4069 N  N   . GLY B 2 211 ? -35.266 -15.076 -7.347  1   25.84  ? 381 GLY B N   1 
ATOM   4070 C  CA  . GLY B 2 211 ? -36.684 -14.758 -7.215  1   28.1   ? 381 GLY B CA  1 
ATOM   4071 C  C   . GLY B 2 211 ? -37.107 -13.411 -7.816  1   28.49  ? 381 GLY B C   1 
ATOM   4072 O  O   . GLY B 2 211 ? -38.293 -13.114 -7.884  1   29.58  ? 381 GLY B O   1 
ATOM   4073 N  N   . TYR B 2 212 ? -36.142 -12.593 -8.252  1   27.49  ? 382 TYR B N   1 
ATOM   4074 C  CA  . TYR B 2 212 ? -36.434 -11.279 -8.804  1   27.94  ? 382 TYR B CA  1 
ATOM   4075 C  C   . TYR B 2 212 ? -36.76  -11.335 -10.296 1   27.7   ? 382 TYR B C   1 
ATOM   4076 O  O   . TYR B 2 212 ? -36.06  -11.99  -11.056 1   29.15  ? 382 TYR B O   1 
ATOM   4077 C  CB  . TYR B 2 212 ? -35.227 -10.347 -8.644  1   28.52  ? 382 TYR B CB  1 
ATOM   4078 C  CG  . TYR B 2 212 ? -34.728 -10.1   -7.237  1   29.61  ? 382 TYR B CG  1 
ATOM   4079 C  CD1 . TYR B 2 212 ? -35.584 -10.194 -6.135  1   28.53  ? 382 TYR B CD1 1 
ATOM   4080 C  CD2 . TYR B 2 212 ? -33.389 -9.782  -6.998  1   26.82  ? 382 TYR B CD2 1 
ATOM   4081 C  CE1 . TYR B 2 212 ? -35.12  -9.941  -4.842  1   26.67  ? 382 TYR B CE1 1 
ATOM   4082 C  CE2 . TYR B 2 212 ? -32.921 -9.53   -5.716  1   24.11  ? 382 TYR B CE2 1 
ATOM   4083 C  CZ  . TYR B 2 212 ? -33.778 -9.623  -4.64   1   24.97  ? 382 TYR B CZ  1 
ATOM   4084 O  OH  . TYR B 2 212 ? -33.259 -9.374  -3.384  1   25.14  ? 382 TYR B OH  1 
ATOM   4085 N  N   . THR B 2 213 ? -37.831 -10.652 -10.698 1   30.23  ? 383 THR B N   1 
ATOM   4086 C  CA  . THR B 2 213 ? -38.185 -10.452 -12.093 1   30.07  ? 383 THR B CA  1 
ATOM   4087 C  C   . THR B 2 213 ? -37.992 -8.987  -12.47  1   32.19  ? 383 THR B C   1 
ATOM   4088 O  O   . THR B 2 213 ? -37.801 -8.14   -11.602 1   36.2   ? 383 THR B O   1 
ATOM   4089 C  CB  . THR B 2 213 ? -39.647 -10.82  -12.325 1   29.42  ? 383 THR B CB  1 
ATOM   4090 O  OG1 . THR B 2 213 ? -40.447 -9.862  -11.613 1   27.01  ? 383 THR B OG1 1 
ATOM   4091 C  CG2 . THR B 2 213 ? -39.98  -12.235 -11.875 1   30.06  ? 383 THR B CG2 1 
ATOM   4092 N  N   . LEU B 2 214 ? -38.099 -8.688  -13.769 1   35.38  ? 384 LEU B N   1 
ATOM   4093 C  CA  . LEU B 2 214 ? -38.096 -7.311  -14.232 1   38.41  ? 384 LEU B CA  1 
ATOM   4094 C  C   . LEU B 2 214 ? -39.197 -6.482  -13.579 1   36.63  ? 384 LEU B C   1 
ATOM   4095 O  O   . LEU B 2 214 ? -39.012 -5.289  -13.383 1   36.64  ? 384 LEU B O   1 
ATOM   4096 C  CB  . LEU B 2 214 ? -38.24  -7.243  -15.754 1   39.53  ? 384 LEU B CB  1 
ATOM   4097 C  CG  . LEU B 2 214 ? -36.997 -7.614  -16.547 1   41.25  ? 384 LEU B CG  1 
ATOM   4098 C  CD1 . LEU B 2 214 ? -37.181 -7.304  -18.007 1   42.03  ? 384 LEU B CD1 1 
ATOM   4099 C  CD2 . LEU B 2 214 ? -35.776 -6.887  -16.028 1   42.91  ? 384 LEU B CD2 1 
ATOM   4100 N  N   . GLU B 2 215 ? -40.325 -7.115  -13.239 1   37.72  ? 385 GLU B N   1 
ATOM   4101 C  CA  . GLU B 2 215 ? -41.363 -6.447  -12.467 1   39.37  ? 385 GLU B CA  1 
ATOM   4102 C  C   . GLU B 2 215 ? -40.849 -6.019  -11.097 1   36.15  ? 385 GLU B C   1 
ATOM   4103 O  O   . GLU B 2 215 ? -40.974 -4.85   -10.748 1   35.32  ? 385 GLU B O   1 
ATOM   4104 C  CB  . GLU B 2 215 ? -42.616 -7.316  -12.294 1   41.02  ? 385 GLU B CB  1 
ATOM   4105 C  CG  . GLU B 2 215 ? -43.408 -7.441  -13.576 1   49.02  ? 385 GLU B CG  1 
ATOM   4106 C  CD  . GLU B 2 215 ? -44.887 -7.742  -13.409 1   58.61  ? 385 GLU B CD  1 
ATOM   4107 O  OE1 . GLU B 2 215 ? -45.333 -8.023  -12.269 1   64.22  ? 385 GLU B OE1 1 
ATOM   4108 O  OE2 . GLU B 2 215 ? -45.606 -7.67   -14.432 1   57.14  ? 385 GLU B OE2 1 
ATOM   4109 N  N   . THR B 2 216 ? -40.264 -6.96   -10.342 1   34.4   ? 386 THR B N   1 
ATOM   4110 C  CA  . THR B 2 216 ? -39.686 -6.667  -9.037  1   35.57  ? 386 THR B CA  1 
ATOM   4111 C  C   . THR B 2 216 ? -38.674 -5.529  -9.086  1   36.59  ? 386 THR B C   1 
ATOM   4112 O  O   . THR B 2 216 ? -38.676 -4.652  -8.224  1   37.37  ? 386 THR B O   1 
ATOM   4113 C  CB  . THR B 2 216 ? -38.965 -7.901  -8.454  1   36.24  ? 386 THR B CB  1 
ATOM   4114 O  OG1 . THR B 2 216 ? -39.958 -8.801  -8.019  1   40.38  ? 386 THR B OG1 1 
ATOM   4115 C  CG2 . THR B 2 216 ? -38.026 -7.57   -7.274  1   41.47  ? 386 THR B CG2 1 
ATOM   4116 N  N   . LEU B 2 217 ? -37.806 -5.577  -10.105 1   37.34  ? 387 LEU B N   1 
ATOM   4117 C  CA  . LEU B 2 217 ? -36.695 -4.647  -10.234 1   34.99  ? 387 LEU B CA  1 
ATOM   4118 C  C   . LEU B 2 217 ? -37.103 -3.311  -10.854 1   31.7   ? 387 LEU B C   1 
ATOM   4119 O  O   . LEU B 2 217 ? -36.309 -2.381  -10.898 1   29.76  ? 387 LEU B O   1 
ATOM   4120 C  CB  . LEU B 2 217 ? -35.619 -5.297  -11.105 1   37.46  ? 387 LEU B CB  1 
ATOM   4121 C  CG  . LEU B 2 217 ? -35.068 -6.637  -10.612 1   37.9   ? 387 LEU B CG  1 
ATOM   4122 C  CD1 . LEU B 2 217 ? -34.102 -7.224  -11.621 1   39.02  ? 387 LEU B CD1 1 
ATOM   4123 C  CD2 . LEU B 2 217 ? -34.403 -6.494  -9.252  1   38.46  ? 387 LEU B CD2 1 
ATOM   4124 N  N   . LYS B 2 218 ? -38.349 -3.214  -11.323 1   31.46  ? 388 LYS B N   1 
ATOM   4125 C  CA  . LYS B 2 218 ? -38.8   -2.067  -12.096 1   31.87  ? 388 LYS B CA  1 
ATOM   4126 C  C   . LYS B 2 218 ? -38.548 -0.729  -11.398 1   31.82  ? 388 LYS B C   1 
ATOM   4127 O  O   . LYS B 2 218 ? -37.944 0.164   -11.986 1   32.4   ? 388 LYS B O   1 
ATOM   4128 C  CB  . LYS B 2 218 ? -40.287 -2.23   -12.468 1   32.62  ? 388 LYS B CB  1 
ATOM   4129 C  CG  . LYS B 2 218 ? -40.749 -1.21   -13.487 1   33.84  ? 388 LYS B CG  1 
ATOM   4130 C  CD  . LYS B 2 218 ? -42.187 -1.339  -13.854 1   34.96  ? 388 LYS B CD  1 
ATOM   4131 C  CE  . LYS B 2 218 ? -42.565 -0.276  -14.863 1   38.86  ? 388 LYS B CE  1 
ATOM   4132 N  NZ  . LYS B 2 218 ? -43.978 -0.4    -15.317 1   39.58  ? 388 LYS B NZ  1 
ATOM   4133 N  N   . PRO B 2 219 ? -38.979 -0.523  -10.13  1   34.56  ? 389 PRO B N   1 
ATOM   4134 C  CA  . PRO B 2 219 ? -38.743 0.759   -9.455  1   33.73  ? 389 PRO B CA  1 
ATOM   4135 C  C   . PRO B 2 219 ? -37.269 1.166   -9.417  1   32.89  ? 389 PRO B C   1 
ATOM   4136 O  O   . PRO B 2 219 ? -36.915 2.281   -9.79   1   34.28  ? 389 PRO B O   1 
ATOM   4137 C  CB  . PRO B 2 219 ? -39.328 0.523   -8.051  1   33.25  ? 389 PRO B CB  1 
ATOM   4138 C  CG  . PRO B 2 219 ? -40.356 -0.585  -8.25   1   31.22  ? 389 PRO B CG  1 
ATOM   4139 C  CD  . PRO B 2 219 ? -39.712 -1.482  -9.279  1   33.66  ? 389 PRO B CD  1 
ATOM   4140 N  N   . CYS B 2 220 ? -36.412 0.235   -8.995  1   34.06  ? 390 CYS B N   1 
ATOM   4141 C  CA  . CYS B 2 220 ? -34.975 0.455   -8.929  1   32.39  ? 390 CYS B CA  1 
ATOM   4142 C  C   . CYS B 2 220 ? -34.381 0.723   -10.312 1   32.56  ? 390 CYS B C   1 
ATOM   4143 O  O   . CYS B 2 220 ? -33.56  1.62    -10.477 1   31.12  ? 390 CYS B O   1 
ATOM   4144 C  CB  . CYS B 2 220 ? -34.3   -0.732  -8.247  1   31.07  ? 390 CYS B CB  1 
ATOM   4145 S  SG  . CYS B 2 220 ? -32.55  -0.48   -7.883  1   33.54  ? 390 CYS B SG  1 
ATOM   4146 N  N   . LEU B 2 221 ? -34.799 -0.069  -11.305 1   33.6   ? 391 LEU B N   1 
ATOM   4147 C  CA  . LEU B 2 221 ? -34.375 0.141   -12.676 1   33.38  ? 391 LEU B CA  1 
ATOM   4148 C  C   . LEU B 2 221 ? -34.662 1.558   -13.156 1   32.51  ? 391 LEU B C   1 
ATOM   4149 O  O   . LEU B 2 221 ? -33.813 2.185   -13.786 1   34     ? 391 LEU B O   1 
ATOM   4150 C  CB  . LEU B 2 221 ? -35.068 -0.835  -13.619 1   34.95  ? 391 LEU B CB  1 
ATOM   4151 C  CG  . LEU B 2 221 ? -34.321 -2.085  -13.888 1   39.22  ? 391 LEU B CG  1 
ATOM   4152 C  CD1 . LEU B 2 221 ? -35.189 -3.051  -14.687 1   40.37  ? 391 LEU B CD1 1 
ATOM   4153 C  CD2 . LEU B 2 221 ? -32.992 -1.79   -14.623 1   39.01  ? 391 LEU B CD2 1 
ATOM   4154 N  N   . LEU B 2 222 ? -35.862 2.058   -12.848 1   30.53  ? 392 LEU B N   1 
ATOM   4155 C  CA  . LEU B 2 222 ? -36.253 3.383   -13.296 1   32.11  ? 392 LEU B CA  1 
ATOM   4156 C  C   . LEU B 2 222 ? -35.396 4.477   -12.665 1   32.79  ? 392 LEU B C   1 
ATOM   4157 O  O   . LEU B 2 222 ? -35.009 5.419   -13.346 1   33.71  ? 392 LEU B O   1 
ATOM   4158 C  CB  . LEU B 2 222 ? -37.743 3.639   -13.027 1   33.06  ? 392 LEU B CB  1 
ATOM   4159 C  CG  . LEU B 2 222 ? -38.714 2.844   -13.908 1   34.03  ? 392 LEU B CG  1 
ATOM   4160 C  CD1 . LEU B 2 222 ? -40.108 3.414   -13.844 1   35.67  ? 392 LEU B CD1 1 
ATOM   4161 C  CD2 . LEU B 2 222 ? -38.273 2.798   -15.359 1   35.16  ? 392 LEU B CD2 1 
ATOM   4162 N  N   . ASP B 2 223 ? -35.072 4.342   -11.375 1   36.57  ? 393 ASP B N   1 
ATOM   4163 C  CA  . ASP B 2 223 ? -34.194 5.306   -10.729 1   35.35  ? 393 ASP B CA  1 
ATOM   4164 C  C   . ASP B 2 223 ? -32.785 5.222   -11.31  1   35.15  ? 393 ASP B C   1 
ATOM   4165 O  O   . ASP B 2 223 ? -32.185 6.249   -11.623 1   35.55  ? 393 ASP B O   1 
ATOM   4166 C  CB  . ASP B 2 223 ? -34.141 5.112   -9.199  1   34.92  ? 393 ASP B CB  1 
ATOM   4167 C  CG  . ASP B 2 223 ? -35.384 5.525   -8.461  1   33.37  ? 393 ASP B CG  1 
ATOM   4168 O  OD1 . ASP B 2 223 ? -35.984 6.55    -8.842  1   36.35  ? 393 ASP B OD1 1 
ATOM   4169 O  OD2 . ASP B 2 223 ? -35.75  4.831   -7.485  1   34.87  ? 393 ASP B OD2 1 
ATOM   4170 N  N   . LEU B 2 224 ? -32.279 3.993   -11.461 1   32.66  ? 394 LEU B N   1 
ATOM   4171 C  CA  . LEU B 2 224 ? -30.916 3.766   -11.921 1   34.72  ? 394 LEU B CA  1 
ATOM   4172 C  C   . LEU B 2 224 ? -30.727 4.201   -13.373 1   32.19  ? 394 LEU B C   1 
ATOM   4173 O  O   . LEU B 2 224 ? -29.649 4.658   -13.741 1   32.55  ? 394 LEU B O   1 
ATOM   4174 C  CB  . LEU B 2 224 ? -30.524 2.283   -11.748 1   33.61  ? 394 LEU B CB  1 
ATOM   4175 C  CG  . LEU B 2 224 ? -29.023 1.98    -11.799 1   33.53  ? 394 LEU B CG  1 
ATOM   4176 C  CD1 . LEU B 2 224 ? -28.294 2.63    -10.654 1   33.89  ? 394 LEU B CD1 1 
ATOM   4177 C  CD2 . LEU B 2 224 ? -28.762 0.489   -11.777 1   32.18  ? 394 LEU B CD2 1 
ATOM   4178 N  N   . HIS B 2 225 ? -31.788 4.08    -14.177 1   29.76  ? 395 HIS B N   1 
ATOM   4179 C  CA  . HIS B 2 225 ? -31.769 4.576   -15.541 1   31.3   ? 395 HIS B CA  1 
ATOM   4180 C  C   . HIS B 2 225 ? -31.678 6.101   -15.55  1   33.8   ? 395 HIS B C   1 
ATOM   4181 O  O   . HIS B 2 225 ? -30.947 6.675   -16.353 1   33.29  ? 395 HIS B O   1 
ATOM   4182 C  CB  . HIS B 2 225 ? -33.012 4.115   -16.304 1   29.63  ? 395 HIS B CB  1 
ATOM   4183 C  CG  . HIS B 2 225 ? -33.002 4.454   -17.763 1   31.35  ? 395 HIS B CG  1 
ATOM   4184 N  ND1 . HIS B 2 225 ? -34.175 4.634   -18.47  1   36.23  ? 395 HIS B ND1 1 
ATOM   4185 C  CD2 . HIS B 2 225 ? -31.96  4.666   -18.594 1   33.63  ? 395 HIS B CD2 1 
ATOM   4186 C  CE1 . HIS B 2 225 ? -33.813 4.936   -19.709 1   35.39  ? 395 HIS B CE1 1 
ATOM   4187 N  NE2 . HIS B 2 225 ? -32.482 4.953   -19.825 1   34.91  ? 395 HIS B NE2 1 
ATOM   4188 N  N   . GLN B 2 226 ? -32.438 6.749   -14.657 1   35.81  ? 396 GLN B N   1 
ATOM   4189 C  CA  . GLN B 2 226 ? -32.388 8.194   -14.508 1   37.77  ? 396 GLN B CA  1 
ATOM   4190 C  C   . GLN B 2 226 ? -30.992 8.64    -14.078 1   35.57  ? 396 GLN B C   1 
ATOM   4191 O  O   . GLN B 2 226 ? -30.449 9.601   -14.619 1   36.39  ? 396 GLN B O   1 
ATOM   4192 C  CB  . GLN B 2 226 ? -33.438 8.675   -13.496 1   42.28  ? 396 GLN B CB  1 
ATOM   4193 C  CG  . GLN B 2 226 ? -33.732 10.14   -13.614 1   52.95  ? 396 GLN B CG  1 
ATOM   4194 C  CD  . GLN B 2 226 ? -34.931 10.611  -12.826 1   66.46  ? 396 GLN B CD  1 
ATOM   4195 O  OE1 . GLN B 2 226 ? -36.061 10.145  -13.027 1   70.55  ? 396 GLN B OE1 1 
ATOM   4196 N  NE2 . GLN B 2 226 ? -34.72  11.592  -11.939 1   75.04  ? 396 GLN B NE2 1 
ATOM   4197 N  N   . THR B 2 227 ? -30.409 7.925   -13.109 1   33     ? 397 THR B N   1 
ATOM   4198 C  CA  . THR B 2 227 ? -29.085 8.259   -12.61  1   32.26  ? 397 THR B CA  1 
ATOM   4199 C  C   . THR B 2 227 ? -28.047 8.19    -13.729 1   31.86  ? 397 THR B C   1 
ATOM   4200 O  O   . THR B 2 227 ? -27.182 9.057   -13.832 1   31.21  ? 397 THR B O   1 
ATOM   4201 C  CB  . THR B 2 227 ? -28.727 7.349   -11.428 1   30.98  ? 397 THR B CB  1 
ATOM   4202 O  OG1 . THR B 2 227 ? -29.577 7.685   -10.329 1   30.47  ? 397 THR B OG1 1 
ATOM   4203 C  CG2 . THR B 2 227 ? -27.261 7.477   -11.009 1   30.58  ? 397 THR B CG2 1 
ATOM   4204 N  N   . TYR B 2 228 ? -28.146 7.136   -14.546 1   32.2   ? 398 TYR B N   1 
ATOM   4205 C  CA  . TYR B 2 228 ? -27.247 6.91    -15.664 1   31.96  ? 398 TYR B CA  1 
ATOM   4206 C  C   . TYR B 2 228 ? -27.363 8.043   -16.685 1   33.55  ? 398 TYR B C   1 
ATOM   4207 O  O   . TYR B 2 228 ? -26.353 8.573   -17.141 1   37.83  ? 398 TYR B O   1 
ATOM   4208 C  CB  . TYR B 2 228 ? -27.569 5.537   -16.297 1   30.8   ? 398 TYR B CB  1 
ATOM   4209 C  CG  . TYR B 2 228 ? -26.577 4.974   -17.3   1   30.14  ? 398 TYR B CG  1 
ATOM   4210 C  CD1 . TYR B 2 228 ? -25.321 5.536   -17.467 1   29.88  ? 398 TYR B CD1 1 
ATOM   4211 C  CD2 . TYR B 2 228 ? -26.902 3.874   -18.079 1   34.2   ? 398 TYR B CD2 1 
ATOM   4212 C  CE1 . TYR B 2 228 ? -24.413 5.011   -18.375 1   31.83  ? 398 TYR B CE1 1 
ATOM   4213 C  CE2 . TYR B 2 228 ? -26.007 3.349   -19.001 1   31.84  ? 398 TYR B CE2 1 
ATOM   4214 C  CZ  . TYR B 2 228 ? -24.762 3.917   -19.144 1   32.76  ? 398 TYR B CZ  1 
ATOM   4215 O  OH  . TYR B 2 228 ? -23.888 3.376   -20.06  1   32.41  ? 398 TYR B OH  1 
ATOM   4216 N  N   . LEU B 2 229 ? -28.601 8.425   -17.028 1   32.86  ? 399 LEU B N   1 
ATOM   4217 C  CA  . LEU B 2 229 ? -28.835 9.482   -18     1   32.72  ? 399 LEU B CA  1 
ATOM   4218 C  C   . LEU B 2 229 ? -28.305 10.824  -17.514 1   31.62  ? 399 LEU B C   1 
ATOM   4219 O  O   . LEU B 2 229 ? -27.751 11.581  -18.304 1   34.41  ? 399 LEU B O   1 
ATOM   4220 C  CB  . LEU B 2 229 ? -30.323 9.627   -18.309 1   33.55  ? 399 LEU B CB  1 
ATOM   4221 C  CG  . LEU B 2 229 ? -30.927 8.587   -19.244 1   34.71  ? 399 LEU B CG  1 
ATOM   4222 C  CD1 . LEU B 2 229 ? -32.423 8.744   -19.308 1   33.97  ? 399 LEU B CD1 1 
ATOM   4223 C  CD2 . LEU B 2 229 ? -30.353 8.711   -20.653 1   36.51  ? 399 LEU B CD2 1 
ATOM   4224 N  N   . ARG B 2 230 ? -28.474 11.099  -16.22  1   32.59  ? 400 ARG B N   1 
ATOM   4225 C  CA  . ARG B 2 230 ? -28.085 12.375  -15.641 1   36.65  ? 400 ARG B CA  1 
ATOM   4226 C  C   . ARG B 2 230 ? -26.619 12.439  -15.221 1   33.7   ? 400 ARG B C   1 
ATOM   4227 O  O   . ARG B 2 230 ? -26.135 13.512  -14.876 1   31.76  ? 400 ARG B O   1 
ATOM   4228 C  CB  . ARG B 2 230 ? -28.982 12.693  -14.423 1   42.95  ? 400 ARG B CB  1 
ATOM   4229 C  CG  . ARG B 2 230 ? -30.378 13.16   -14.817 1   52.79  ? 400 ARG B CG  1 
ATOM   4230 C  CD  . ARG B 2 230 ? -31.425 12.895  -13.734 1   59.8   ? 400 ARG B CD  1 
ATOM   4231 N  NE  . ARG B 2 230 ? -32.752 13.419  -14.061 1   71.35  ? 400 ARG B NE  1 
ATOM   4232 C  CZ  . ARG B 2 230 ? -33.499 13.076  -15.113 1   76.68  ? 400 ARG B CZ  1 
ATOM   4233 N  NH1 . ARG B 2 230 ? -33.041 12.284  -16.072 1   76.32  ? 400 ARG B NH1 1 
ATOM   4234 N  NH2 . ARG B 2 230 ? -34.74  13.547  -15.204 1   76.02  ? 400 ARG B NH2 1 
ATOM   4235 N  N   . ALA B 2 231 ? -25.916 11.299  -15.263 1   32.39  ? 401 ALA B N   1 
ATOM   4236 C  CA  . ALA B 2 231 ? -24.601 11.186  -14.648 1   32.71  ? 401 ALA B CA  1 
ATOM   4237 C  C   . ALA B 2 231 ? -23.6   12.251  -15.118 1   33.17  ? 401 ALA B C   1 
ATOM   4238 O  O   . ALA B 2 231 ? -22.869 12.808  -14.303 1   31.5   ? 401 ALA B O   1 
ATOM   4239 C  CB  . ALA B 2 231 ? -24.048 9.779   -14.861 1   31.43  ? 401 ALA B CB  1 
ATOM   4240 N  N   . PRO B 2 232 ? -23.527 12.592  -16.427 1   29.97  ? 402 PRO B N   1 
ATOM   4241 C  CA  . PRO B 2 232 ? -22.678 13.703  -16.87  1   31.46  ? 402 PRO B CA  1 
ATOM   4242 C  C   . PRO B 2 232 ? -22.958 15.047  -16.19  1   31.04  ? 402 PRO B C   1 
ATOM   4243 O  O   . PRO B 2 232 ? -22.079 15.902  -16.131 1   28.8   ? 402 PRO B O   1 
ATOM   4244 C  CB  . PRO B 2 232 ? -22.969 13.793  -18.384 1   31.06  ? 402 PRO B CB  1 
ATOM   4245 C  CG  . PRO B 2 232 ? -23.502 12.435  -18.771 1   30.51  ? 402 PRO B CG  1 
ATOM   4246 C  CD  . PRO B 2 232 ? -24.212 11.908  -17.539 1   29.75  ? 402 PRO B CD  1 
ATOM   4247 N  N   . GLN B 2 233 ? -24.19  15.231  -15.697 1   30.57  ? 403 GLN B N   1 
ATOM   4248 C  CA  . GLN B 2 233 ? -24.626 16.478  -15.08  1   31.62  ? 403 GLN B CA  1 
ATOM   4249 C  C   . GLN B 2 233 ? -24.437 16.49   -13.561 1   31.05  ? 403 GLN B C   1 
ATOM   4250 O  O   . GLN B 2 233 ? -24.464 17.549  -12.946 1   30.52  ? 403 GLN B O   1 
ATOM   4251 C  CB  . GLN B 2 233 ? -26.13  16.758  -15.357 1   34.46  ? 403 GLN B CB  1 
ATOM   4252 C  CG  . GLN B 2 233 ? -26.457 17.493  -16.649 1   39.89  ? 403 GLN B CG  1 
ATOM   4253 C  CD  . GLN B 2 233 ? -25.897 16.802  -17.85  1   44.23  ? 403 GLN B CD  1 
ATOM   4254 O  OE1 . GLN B 2 233 ? -24.93  17.275  -18.462 1   45.18  ? 403 GLN B OE1 1 
ATOM   4255 N  NE2 . GLN B 2 233 ? -26.462 15.645  -18.186 1   46.51  ? 403 GLN B NE2 1 
ATOM   4256 N  N   . HIS B 2 234 ? -24.296 15.307  -12.951 1   30.13  ? 404 HIS B N   1 
ATOM   4257 C  CA  . HIS B 2 234 ? -24.229 15.204  -11.505 1   30.79  ? 404 HIS B CA  1 
ATOM   4258 C  C   . HIS B 2 234 ? -23.077 16.067  -10.996 1   28.92  ? 404 HIS B C   1 
ATOM   4259 O  O   . HIS B 2 234 ? -22.053 16.176  -11.659 1   27.2   ? 404 HIS B O   1 
ATOM   4260 C  CB  . HIS B 2 234 ? -24.058 13.738  -11.09  1   31.79  ? 404 HIS B CB  1 
ATOM   4261 C  CG  . HIS B 2 234 ? -24.404 13.446  -9.661  1   33.58  ? 404 HIS B CG  1 
ATOM   4262 N  ND1 . HIS B 2 234 ? -23.631 13.92   -8.622  1   31.11  ? 404 HIS B ND1 1 
ATOM   4263 C  CD2 . HIS B 2 234 ? -25.426 12.709  -9.15   1   31.06  ? 404 HIS B CD2 1 
ATOM   4264 C  CE1 . HIS B 2 234 ? -24.199 13.454  -7.512  1   32.67  ? 404 HIS B CE1 1 
ATOM   4265 N  NE2 . HIS B 2 234 ? -25.284 12.723  -7.789  1   31.03  ? 404 HIS B NE2 1 
ATOM   4266 N  N   . ALA B 2 235 ? -23.256 16.68   -9.819  1   27.7   ? 405 ALA B N   1 
ATOM   4267 C  CA  . ALA B 2 235 ? -22.206 17.473  -9.2    1   26.54  ? 405 ALA B CA  1 
ATOM   4268 C  C   . ALA B 2 235 ? -20.947 16.652  -8.902  1   27.13  ? 405 ALA B C   1 
ATOM   4269 O  O   . ALA B 2 235 ? -19.843 17.169  -9.014  1   28.15  ? 405 ALA B O   1 
ATOM   4270 C  CB  . ALA B 2 235 ? -22.735 18.114  -7.925  1   25.48  ? 405 ALA B CB  1 
ATOM   4271 N  N   . GLN B 2 236 ? -21.123 15.377  -8.529  1   26.88  ? 406 GLN B N   1 
ATOM   4272 C  CA  . GLN B 2 236 ? -20.015 14.464  -8.284  1   29.11  ? 406 GLN B CA  1 
ATOM   4273 C  C   . GLN B 2 236 ? -19.638 13.642  -9.52   1   29.8   ? 406 GLN B C   1 
ATOM   4274 O  O   . GLN B 2 236 ? -20.485 12.952  -10.095 1   28.44  ? 406 GLN B O   1 
ATOM   4275 C  CB  . GLN B 2 236 ? -20.374 13.51   -7.132  1   30.03  ? 406 GLN B CB  1 
ATOM   4276 C  CG  . GLN B 2 236 ? -20.122 14.086  -5.742  1   33.34  ? 406 GLN B CG  1 
ATOM   4277 C  CD  . GLN B 2 236 ? -20.932 15.305  -5.409  1   35.25  ? 406 GLN B CD  1 
ATOM   4278 O  OE1 . GLN B 2 236 ? -20.398 16.367  -5.053  1   38.56  ? 406 GLN B OE1 1 
ATOM   4279 N  NE2 . GLN B 2 236 ? -22.23  15.17   -5.485  1   33.19  ? 406 GLN B NE2 1 
ATOM   4280 N  N   . GLN B 2 237 ? -18.347 13.682  -9.887  1   28.18  ? 407 GLN B N   1 
ATOM   4281 C  CA  . GLN B 2 237 ? -17.879 13.111  -11.142 1   28.36  ? 407 GLN B CA  1 
ATOM   4282 C  C   . GLN B 2 237 ? -16.753 12.086  -11.033 1   28.63  ? 407 GLN B C   1 
ATOM   4283 O  O   . GLN B 2 237 ? -16.28  11.583  -12.048 1   29.16  ? 407 GLN B O   1 
ATOM   4284 C  CB  . GLN B 2 237 ? -17.404 14.242  -12.06  1   26.5   ? 407 GLN B CB  1 
ATOM   4285 C  CG  . GLN B 2 237 ? -18.523 15.163  -12.557 1   27.13  ? 407 GLN B CG  1 
ATOM   4286 C  CD  . GLN B 2 237 ? -19.453 14.454  -13.499 1   26.9   ? 407 GLN B CD  1 
ATOM   4287 O  OE1 . GLN B 2 237 ? -19.021 13.722  -14.371 1   28.25  ? 407 GLN B OE1 1 
ATOM   4288 N  NE2 . GLN B 2 237 ? -20.755 14.618  -13.333 1   27.1   ? 407 GLN B NE2 1 
ATOM   4289 N  N   . SER B 2 238 ? -16.326 11.767  -9.807  1   29.02  ? 408 SER B N   1 
ATOM   4290 C  CA  . SER B 2 238 ? -15.143 10.937  -9.632  1   29.93  ? 408 SER B CA  1 
ATOM   4291 C  C   . SER B 2 238 ? -15.33  9.516   -10.164 1   28.31  ? 408 SER B C   1 
ATOM   4292 O  O   . SER B 2 238 ? -14.373 8.899   -10.629 1   26.41  ? 408 SER B O   1 
ATOM   4293 C  CB  . SER B 2 238 ? -14.719 10.896  -8.169  1   28.57  ? 408 SER B CB  1 
ATOM   4294 O  OG  . SER B 2 238 ? -14.39  12.194  -7.702  1   28.36  ? 408 SER B OG  1 
ATOM   4295 N  N   . ILE B 2 239 ? -16.559 8.999   -10.102 1   26.48  ? 409 ILE B N   1 
ATOM   4296 C  CA  . ILE B 2 239 ? -16.826 7.661   -10.606 1   28.64  ? 409 ILE B CA  1 
ATOM   4297 C  C   . ILE B 2 239 ? -16.755 7.648   -12.135 1   29.16  ? 409 ILE B C   1 
ATOM   4298 O  O   . ILE B 2 239 ? -16.17  6.732   -12.72  1   27.46  ? 409 ILE B O   1 
ATOM   4299 C  CB  . ILE B 2 239 ? -18.163 7.098   -10.042 1   28.42  ? 409 ILE B CB  1 
ATOM   4300 C  CG1 . ILE B 2 239 ? -18.117 6.989   -8.52   1   28.17  ? 409 ILE B CG1 1 
ATOM   4301 C  CG2 . ILE B 2 239 ? -18.496 5.762   -10.632 1   28.66  ? 409 ILE B CG2 1 
ATOM   4302 C  CD1 . ILE B 2 239 ? -19.394 6.645   -7.882  1   28.58  ? 409 ILE B CD1 1 
ATOM   4303 N  N   . ARG B 2 240 ? -17.317 8.676   -12.783 1   26.48  ? 410 ARG B N   1 
ATOM   4304 C  CA  . ARG B 2 240 ? -17.227 8.764   -14.232 1   28.21  ? 410 ARG B CA  1 
ATOM   4305 C  C   . ARG B 2 240 ? -15.773 8.827   -14.682 1   27.54  ? 410 ARG B C   1 
ATOM   4306 O  O   . ARG B 2 240 ? -15.402 8.129   -15.627 1   27.27  ? 410 ARG B O   1 
ATOM   4307 C  CB  . ARG B 2 240 ? -18     9.952   -14.806 1   31.28  ? 410 ARG B CB  1 
ATOM   4308 C  CG  . ARG B 2 240 ? -19.501 9.693   -14.83  1   35.48  ? 410 ARG B CG  1 
ATOM   4309 C  CD  . ARG B 2 240 ? -20.285 10.777  -15.54  1   37.18  ? 410 ARG B CD  1 
ATOM   4310 N  NE  . ARG B 2 240 ? -20.09  10.707  -16.982 1   34.36  ? 410 ARG B NE  1 
ATOM   4311 C  CZ  . ARG B 2 240 ? -19.571 11.676  -17.721 1   33.75  ? 410 ARG B CZ  1 
ATOM   4312 N  NH1 . ARG B 2 240 ? -19.146 12.804  -17.185 1   33.04  ? 410 ARG B NH1 1 
ATOM   4313 N  NH2 . ARG B 2 240 ? -19.459 11.5    -19.031 1   33.99  ? 410 ARG B NH2 1 
ATOM   4314 N  N   . GLU B 2 241 ? -14.966 9.655   -14     1   28.46  ? 411 GLU B N   1 
ATOM   4315 C  CA  . GLU B 2 241 ? -13.547 9.776   -14.308 1   32.7   ? 411 GLU B CA  1 
ATOM   4316 C  C   . GLU B 2 241 ? -12.843 8.427   -14.165 1   31.14  ? 411 GLU B C   1 
ATOM   4317 O  O   . GLU B 2 241 ? -12.126 7.986   -15.064 1   32.12  ? 411 GLU B O   1 
ATOM   4318 C  CB  . GLU B 2 241 ? -12.851 10.816  -13.398 1   33.91  ? 411 GLU B CB  1 
ATOM   4319 C  CG  . GLU B 2 241 ? -13.237 12.27   -13.647 1   35.33  ? 411 GLU B CG  1 
ATOM   4320 C  CD  . GLU B 2 241 ? -13.05  12.72   -15.08  1   40.78  ? 411 GLU B CD  1 
ATOM   4321 O  OE1 . GLU B 2 241 ? -11.962 12.464  -15.649 1   41.56  ? 411 GLU B OE1 1 
ATOM   4322 O  OE2 . GLU B 2 241 ? -13.988 13.329  -15.643 1   45.13  ? 411 GLU B OE2 1 
ATOM   4323 N  N   . LYS B 2 242 ? -13.083 7.77    -13.031 1   29.27  ? 412 LYS B N   1 
ATOM   4324 C  CA  . LYS B 2 242 ? -12.472 6.492   -12.72  1   29.6   ? 412 LYS B CA  1 
ATOM   4325 C  C   . LYS B 2 242 ? -12.772 5.455   -13.8   1   30.3   ? 412 LYS B C   1 
ATOM   4326 O  O   . LYS B 2 242 ? -11.864 4.757   -14.243 1   29.43  ? 412 LYS B O   1 
ATOM   4327 C  CB  . LYS B 2 242 ? -12.963 6.04    -11.339 1   28.39  ? 412 LYS B CB  1 
ATOM   4328 C  CG  . LYS B 2 242 ? -12.699 4.588   -10.944 1   28.4   ? 412 LYS B CG  1 
ATOM   4329 C  CD  . LYS B 2 242 ? -13.345 4.291   -9.586  1   29.48  ? 412 LYS B CD  1 
ATOM   4330 C  CE  . LYS B 2 242 ? -13.196 2.866   -9.139  1   29.06  ? 412 LYS B CE  1 
ATOM   4331 N  NZ  . LYS B 2 242 ? -13.898 2.627   -7.853  1   30.21  ? 412 LYS B NZ  1 
ATOM   4332 N  N   . TYR B 2 243 ? -14.035 5.385   -14.244 1   28.12  ? 413 TYR B N   1 
ATOM   4333 C  CA  . TYR B 2 243 ? -14.435 4.38    -15.211 1   28.25  ? 413 TYR B CA  1 
ATOM   4334 C  C   . TYR B 2 243 ? -14.193 4.773   -16.672 1   27.66  ? 413 TYR B C   1 
ATOM   4335 O  O   . TYR B 2 243 ? -14.565 4.017   -17.562 1   28.88  ? 413 TYR B O   1 
ATOM   4336 C  CB  . TYR B 2 243 ? -15.912 3.964   -14.967 1   28.11  ? 413 TYR B CB  1 
ATOM   4337 C  CG  . TYR B 2 243 ? -16.055 2.981   -13.824 1   28.65  ? 413 TYR B CG  1 
ATOM   4338 C  CD1 . TYR B 2 243 ? -16.037 3.412   -12.507 1   29.35  ? 413 TYR B CD1 1 
ATOM   4339 C  CD2 . TYR B 2 243 ? -16.154 1.613   -14.06  1   29.61  ? 413 TYR B CD2 1 
ATOM   4340 C  CE1 . TYR B 2 243 ? -16.154 2.519   -11.453 1   28.08  ? 413 TYR B CE1 1 
ATOM   4341 C  CE2 . TYR B 2 243 ? -16.278 0.707   -13.014 1   29.11  ? 413 TYR B CE2 1 
ATOM   4342 C  CZ  . TYR B 2 243 ? -16.266 1.164   -11.708 1   29.6   ? 413 TYR B CZ  1 
ATOM   4343 O  OH  . TYR B 2 243 ? -16.349 0.282   -10.659 1   26.11  ? 413 TYR B OH  1 
ATOM   4344 N  N   . LYS B 2 244 ? -13.539 5.915   -16.932 1   27.64  ? 414 LYS B N   1 
ATOM   4345 C  CA  . LYS B 2 244 ? -12.985 6.185   -18.254 1   29.85  ? 414 LYS B CA  1 
ATOM   4346 C  C   . LYS B 2 244 ? -11.726 5.362   -18.538 1   30.96  ? 414 LYS B C   1 
ATOM   4347 O  O   . LYS B 2 244 ? -11.345 5.172   -19.686 1   34.35  ? 414 LYS B O   1 
ATOM   4348 C  CB  . LYS B 2 244 ? -12.593 7.654   -18.427 1   31.53  ? 414 LYS B CB  1 
ATOM   4349 C  CG  . LYS B 2 244 ? -13.731 8.65    -18.392 1   32.02  ? 414 LYS B CG  1 
ATOM   4350 C  CD  . LYS B 2 244 ? -13.192 10.073  -18.503 1   31.45  ? 414 LYS B CD  1 
ATOM   4351 C  CE  . LYS B 2 244 ? -14.256 11.101  -18.203 1   34.29  ? 414 LYS B CE  1 
ATOM   4352 N  NZ  . LYS B 2 244 ? -13.744 12.486  -18.397 1   34.8   ? 414 LYS B NZ  1 
ATOM   4353 N  N   . ASN B 2 245 ? -11.075 4.898   -17.472 1   32.03  ? 415 ASN B N   1 
ATOM   4354 C  CA  . ASN B 2 245 ? -9.82   4.177   -17.538 1   35.42  ? 415 ASN B CA  1 
ATOM   4355 C  C   . ASN B 2 245 ? -9.94   2.791   -18.169 1   34.52  ? 415 ASN B C   1 
ATOM   4356 O  O   . ASN B 2 245 ? -10.926 2.087   -17.947 1   34.41  ? 415 ASN B O   1 
ATOM   4357 C  CB  . ASN B 2 245 ? -9.278  4.067   -16.102 1   36.54  ? 415 ASN B CB  1 
ATOM   4358 C  CG  . ASN B 2 245 ? -7.855  3.602   -15.989 1   43.57  ? 415 ASN B CG  1 
ATOM   4359 O  OD1 . ASN B 2 245 ? -7.522  2.444   -16.268 1   51.64  ? 415 ASN B OD1 1 
ATOM   4360 N  ND2 . ASN B 2 245 ? -6.979  4.493   -15.548 1   46.65  ? 415 ASN B ND2 1 
ATOM   4361 N  N   . SER B 2 246 ? -8.897  2.404   -18.914 1   33.08  ? 416 SER B N   1 
ATOM   4362 C  CA  . SER B 2 246 ? -8.855  1.12    -19.598 1   35.08  ? 416 SER B CA  1 
ATOM   4363 C  C   . SER B 2 246 ? -9      -0.066  -18.645 1   34.65  ? 416 SER B C   1 
ATOM   4364 O  O   . SER B 2 246 ? -9.475  -1.124  -19.043 1   32.96  ? 416 SER B O   1 
ATOM   4365 C  CB  . SER B 2 246 ? -7.577  0.98    -20.41  1   37.58  ? 416 SER B CB  1 
ATOM   4366 O  OG  . SER B 2 246 ? -6.429  1.001   -19.577 1   48.65  ? 416 SER B OG  1 
ATOM   4367 N  N   . LYS B 2 247 ? -8.617  0.113   -17.379 1   35.08  ? 417 LYS B N   1 
ATOM   4368 C  CA  . LYS B 2 247 ? -8.826  -0.907  -16.364 1   39.62  ? 417 LYS B CA  1 
ATOM   4369 C  C   . LYS B 2 247 ? -10.278 -1.386  -16.326 1   37.62  ? 417 LYS B C   1 
ATOM   4370 O  O   . LYS B 2 247 ? -10.534 -2.569  -16.137 1   37.36  ? 417 LYS B O   1 
ATOM   4371 C  CB  . LYS B 2 247 ? -8.4    -0.343  -14.998 1   47.46  ? 417 LYS B CB  1 
ATOM   4372 C  CG  . LYS B 2 247 ? -8.686  -1.248  -13.813 1   51.9   ? 417 LYS B CG  1 
ATOM   4373 C  CD  . LYS B 2 247 ? -8.011  -0.733  -12.54  1   58.49  ? 417 LYS B CD  1 
ATOM   4374 C  CE  . LYS B 2 247 ? -8.332  -1.576  -11.329 1   65.03  ? 417 LYS B CE  1 
ATOM   4375 N  NZ  . LYS B 2 247 ? -8.031  -3.011  -11.571 1   70.7   ? 417 LYS B NZ  1 
ATOM   4376 N  N   . TYR B 2 248 ? -11.223 -0.456  -16.516 1   35.38  ? 418 TYR B N   1 
ATOM   4377 C  CA  . TYR B 2 248 ? -12.647 -0.763  -16.539 1   34.97  ? 418 TYR B CA  1 
ATOM   4378 C  C   . TYR B 2 248 ? -13.246 -0.599  -17.936 1   33.47  ? 418 TYR B C   1 
ATOM   4379 O  O   . TYR B 2 248 ? -14.438 -0.337  -18.076 1   32.8   ? 418 TYR B O   1 
ATOM   4380 C  CB  . TYR B 2 248 ? -13.402 0.149   -15.548 1   37.5   ? 418 TYR B CB  1 
ATOM   4381 C  CG  . TYR B 2 248 ? -12.782 0.213   -14.168 1   38.38  ? 418 TYR B CG  1 
ATOM   4382 C  CD1 . TYR B 2 248 ? -12.926 -0.837  -13.272 1   37.18  ? 418 TYR B CD1 1 
ATOM   4383 C  CD2 . TYR B 2 248 ? -12.023 1.31    -13.774 1   37.86  ? 418 TYR B CD2 1 
ATOM   4384 C  CE1 . TYR B 2 248 ? -12.331 -0.799  -12.013 1   39.06  ? 418 TYR B CE1 1 
ATOM   4385 C  CE2 . TYR B 2 248 ? -11.422 1.357   -12.52  1   40.85  ? 418 TYR B CE2 1 
ATOM   4386 C  CZ  . TYR B 2 248 ? -11.584 0.303   -11.639 1   40.68  ? 418 TYR B CZ  1 
ATOM   4387 O  OH  . TYR B 2 248 ? -10.983 0.377   -10.408 1   48.5   ? 418 TYR B OH  1 
ATOM   4388 N  N   . HIS B 2 249 ? -12.407 -0.752  -18.964 1   29.98  ? 419 HIS B N   1 
ATOM   4389 C  CA  . HIS B 2 249 ? -12.846 -0.795  -20.348 1   31.03  ? 419 HIS B CA  1 
ATOM   4390 C  C   . HIS B 2 249 ? -13.525 0.49    -20.812 1   31.17  ? 419 HIS B C   1 
ATOM   4391 O  O   . HIS B 2 249 ? -14.238 0.474   -21.804 1   32.46  ? 419 HIS B O   1 
ATOM   4392 C  CB  . HIS B 2 249 ? -13.75  -2.022  -20.568 1   32.04  ? 419 HIS B CB  1 
ATOM   4393 C  CG  . HIS B 2 249 ? -13.12  -3.299  -20.098 1   35.06  ? 419 HIS B CG  1 
ATOM   4394 N  ND1 . HIS B 2 249 ? -13.439 -3.863  -18.852 1   36.56  ? 419 HIS B ND1 1 
ATOM   4395 C  CD2 . HIS B 2 249 ? -12.16  -4.053  -20.683 1   33.5   ? 419 HIS B CD2 1 
ATOM   4396 C  CE1 . HIS B 2 249 ? -12.682 -4.951  -18.741 1   37.55  ? 419 HIS B CE1 1 
ATOM   4397 N  NE2 . HIS B 2 249 ? -11.898 -5.109  -19.823 1   35.36  ? 419 HIS B NE2 1 
ATOM   4398 N  N   . GLY B 2 250 ? -13.254 1.61    -20.125 1   32.49  ? 420 GLY B N   1 
ATOM   4399 C  CA  . GLY B 2 250 ? -13.791 2.908   -20.508 1   30.73  ? 420 GLY B CA  1 
ATOM   4400 C  C   . GLY B 2 250 ? -15.319 2.964   -20.586 1   30.66  ? 420 GLY B C   1 
ATOM   4401 O  O   . GLY B 2 250 ? -15.876 3.697   -21.403 1   27.42  ? 420 GLY B O   1 
ATOM   4402 N  N   . VAL B 2 251 ? -15.993 2.204   -19.708 1   27.99  ? 421 VAL B N   1 
ATOM   4403 C  CA  . VAL B 2 251 ? -17.436 2.051   -19.791 1   27.51  ? 421 VAL B CA  1 
ATOM   4404 C  C   . VAL B 2 251 ? -18.202 3.345   -19.507 1   28.8   ? 421 VAL B C   1 
ATOM   4405 O  O   . VAL B 2 251 ? -19.306 3.537   -20.01  1   30.3   ? 421 VAL B O   1 
ATOM   4406 C  CB  . VAL B 2 251 ? -17.95  0.914   -18.91  1   28.99  ? 421 VAL B CB  1 
ATOM   4407 C  CG1 . VAL B 2 251 ? -17.515 -0.437  -19.464 1   29.38  ? 421 VAL B CG1 1 
ATOM   4408 C  CG2 . VAL B 2 251 ? -17.532 1.079   -17.459 1   30.94  ? 421 VAL B CG2 1 
ATOM   4409 N  N   . SER B 2 252 ? -17.619 4.263   -18.735 1   27.52  ? 422 SER B N   1 
ATOM   4410 C  CA  . SER B 2 252 ? -18.305 5.515   -18.457 1   28.47  ? 422 SER B CA  1 
ATOM   4411 C  C   . SER B 2 252 ? -18.485 6.349   -19.724 1   28.56  ? 422 SER B C   1 
ATOM   4412 O  O   . SER B 2 252 ? -19.282 7.275   -19.735 1   29.34  ? 422 SER B O   1 
ATOM   4413 C  CB  . SER B 2 252 ? -17.599 6.312   -17.368 1   26.99  ? 422 SER B CB  1 
ATOM   4414 O  OG  . SER B 2 252 ? -16.349 6.811   -17.791 1   29.05  ? 422 SER B OG  1 
ATOM   4415 N  N   . LEU B 2 253 ? -17.763 6.001   -20.795 1   31.23  ? 423 LEU B N   1 
ATOM   4416 C  CA  . LEU B 2 253 ? -17.906 6.662   -22.089 1   31.08  ? 423 LEU B CA  1 
ATOM   4417 C  C   . LEU B 2 253 ? -19.015 6.068   -22.963 1   31.7   ? 423 LEU B C   1 
ATOM   4418 O  O   . LEU B 2 253 ? -19.379 6.668   -23.971 1   31.15  ? 423 LEU B O   1 
ATOM   4419 C  CB  . LEU B 2 253 ? -16.587 6.589   -22.867 1   31.91  ? 423 LEU B CB  1 
ATOM   4420 C  CG  . LEU B 2 253 ? -15.36  7.283   -22.222 1   35.66  ? 423 LEU B CG  1 
ATOM   4421 C  CD1 . LEU B 2 253 ? -14.123 7.038   -23.05  1   35.88  ? 423 LEU B CD1 1 
ATOM   4422 C  CD2 . LEU B 2 253 ? -15.569 8.807   -22.031 1   38.1   ? 423 LEU B CD2 1 
ATOM   4423 N  N   . LEU B 2 254 ? -19.55  4.893   -22.587 1   30.86  ? 424 LEU B N   1 
ATOM   4424 C  CA  . LEU B 2 254 ? -20.659 4.293   -23.316 1   29.77  ? 424 LEU B CA  1 
ATOM   4425 C  C   . LEU B 2 254 ? -21.904 5.167   -23.19  1   29.2   ? 424 LEU B C   1 
ATOM   4426 O  O   . LEU B 2 254 ? -22.142 5.761   -22.145 1   35.08  ? 424 LEU B O   1 
ATOM   4427 C  CB  . LEU B 2 254 ? -20.963 2.87    -22.791 1   28.34  ? 424 LEU B CB  1 
ATOM   4428 C  CG  . LEU B 2 254 ? -19.968 1.772   -23.143 1   27.94  ? 424 LEU B CG  1 
ATOM   4429 C  CD1 . LEU B 2 254 ? -20.401 0.438   -22.563 1   28.96  ? 424 LEU B CD1 1 
ATOM   4430 C  CD2 . LEU B 2 254 ? -19.797 1.656   -24.653 1   28.57  ? 424 LEU B CD2 1 
ATOM   4431 N  N   . ASN B 2 255 ? -22.685 5.261   -24.264 1   29.95  ? 425 ASN B N   1 
ATOM   4432 C  CA  . ASN B 2 255 ? -23.92  6.024   -24.227 1   31.23  ? 425 ASN B CA  1 
ATOM   4433 C  C   . ASN B 2 255 ? -25.028 5.253   -23.52  1   28.84  ? 425 ASN B C   1 
ATOM   4434 O  O   . ASN B 2 255 ? -25.28  4.095   -23.829 1   28.83  ? 425 ASN B O   1 
ATOM   4435 C  CB  . ASN B 2 255 ? -24.393 6.382   -25.615 1   33.47  ? 425 ASN B CB  1 
ATOM   4436 C  CG  . ASN B 2 255 ? -23.516 7.363   -26.294 1   34.2   ? 425 ASN B CG  1 
ATOM   4437 O  OD1 . ASN B 2 255 ? -23.256 7.213   -27.49  1   38.13  ? 425 ASN B OD1 1 
ATOM   4438 N  ND2 . ASN B 2 255 ? -23.084 8.399   -25.554 1   31.82  ? 425 ASN B ND2 1 
ATOM   4439 N  N   . PRO B 2 256 ? -25.749 5.884   -22.574 1   28.03  ? 426 PRO B N   1 
ATOM   4440 C  CA  . PRO B 2 256 ? -26.915 5.244   -21.973 1   27.69  ? 426 PRO B CA  1 
ATOM   4441 C  C   . PRO B 2 256 ? -28.06  5.102   -22.975 1   28.01  ? 426 PRO B C   1 
ATOM   4442 O  O   . PRO B 2 256 ? -28.225 5.946   -23.85  1   27.16  ? 426 PRO B O   1 
ATOM   4443 C  CB  . PRO B 2 256 ? -27.238 6.166   -20.797 1   26.9   ? 426 PRO B CB  1 
ATOM   4444 C  CG  . PRO B 2 256 ? -26.735 7.503   -21.216 1   27.84  ? 426 PRO B CG  1 
ATOM   4445 C  CD  . PRO B 2 256 ? -25.51  7.244   -22.062 1   27.85  ? 426 PRO B CD  1 
ATOM   4446 N  N   . PRO B 2 257 ? -28.9   4.049   -22.863 1   28.93  ? 427 PRO B N   1 
ATOM   4447 C  CA  . PRO B 2 257 ? -30.08  3.914   -23.722 1   28.33  ? 427 PRO B CA  1 
ATOM   4448 C  C   . PRO B 2 257 ? -31.153 4.922   -23.326 1   29.34  ? 427 PRO B C   1 
ATOM   4449 O  O   . PRO B 2 257 ? -31.362 5.161   -22.141 1   27.23  ? 427 PRO B O   1 
ATOM   4450 C  CB  . PRO B 2 257 ? -30.538 2.479   -23.453 1   27.71  ? 427 PRO B CB  1 
ATOM   4451 C  CG  . PRO B 2 257 ? -30.097 2.224   -21.99  1   28.27  ? 427 PRO B CG  1 
ATOM   4452 C  CD  . PRO B 2 257 ? -28.799 2.985   -21.848 1   28.62  ? 427 PRO B CD  1 
ATOM   4453 N  N   . GLU B 2 258 ? -31.854 5.469   -24.32  1   36.69  ? 428 GLU B N   1 
ATOM   4454 C  CA  . GLU B 2 258 ? -32.898 6.46    -24.098 1   39.53  ? 428 GLU B CA  1 
ATOM   4455 C  C   . GLU B 2 258 ? -34.152 5.875   -23.441 1   38.27  ? 428 GLU B C   1 
ATOM   4456 O  O   . GLU B 2 258 ? -34.879 6.609   -22.774 1   41.34  ? 428 GLU B O   1 
ATOM   4457 C  CB  . GLU B 2 258 ? -33.298 7.121   -25.428 1   41.1   ? 428 GLU B CB  1 
ATOM   4458 C  CG  . GLU B 2 258 ? -32.166 7.735   -26.239 1   43.86  ? 428 GLU B CG  1 
ATOM   4459 C  CD  . GLU B 2 258 ? -32.521 8.091   -27.687 1   48.47  ? 428 GLU B CD  1 
ATOM   4460 O  OE1 . GLU B 2 258 ? -33.706 7.974   -28.082 1   47.31  ? 428 GLU B OE1 1 
ATOM   4461 O  OE2 . GLU B 2 258 ? -31.596 8.471   -28.44  1   49.01  ? 428 GLU B OE2 1 
ATOM   4462 N  N   . THR B 2 259 ? -34.396 4.567   -23.642 1   37.76  ? 429 THR B N   1 
ATOM   4463 C  CA  . THR B 2 259 ? -35.575 3.88    -23.127 1   37.56  ? 429 THR B CA  1 
ATOM   4464 C  C   . THR B 2 259 ? -35.256 2.423   -22.793 1   41.95  ? 429 THR B C   1 
ATOM   4465 O  O   . THR B 2 259 ? -34.3   1.862   -23.323 1   44.68  ? 429 THR B O   1 
ATOM   4466 C  CB  . THR B 2 259 ? -36.733 3.919   -24.15  1   36.74  ? 429 THR B CB  1 
ATOM   4467 O  OG1 . THR B 2 259 ? -36.385 3.095   -25.269 1   32.16  ? 429 THR B OG1 1 
ATOM   4468 C  CG2 . THR B 2 259 ? -37.07  5.336   -24.612 1   36.85  ? 429 THR B CG2 1 
ATOM   4469 N  N   . LEU B 2 260 ? -36.084 1.796   -21.947 1   45.93  ? 430 LEU B N   1 
ATOM   4470 C  CA  . LEU B 2 260 ? -35.836 0.434   -21.496 1   47.97  ? 430 LEU B CA  1 
ATOM   4471 C  C   . LEU B 2 260 ? -36.773 -0.639  -22.045 1   53.81  ? 430 LEU B C   1 
ATOM   4472 O  O   . LEU B 2 260 ? -36.43  -1.819  -22.013 1   52.69  ? 430 LEU B O   1 
ATOM   4473 C  CB  . LEU B 2 260 ? -35.918 0.419   -19.972 1   48.25  ? 430 LEU B CB  1 
ATOM   4474 C  CG  . LEU B 2 260 ? -34.9   1.272   -19.263 1   49.03  ? 430 LEU B CG  1 
ATOM   4475 C  CD1 . LEU B 2 260 ? -35.025 1.108   -17.766 1   49.45  ? 430 LEU B CD1 1 
ATOM   4476 C  CD2 . LEU B 2 260 ? -33.481 0.945   -19.725 1   48.11  ? 430 LEU B CD2 1 
ATOM   4477 N  N   . ASN B 2 261 ? -37.961 -0.23   -22.512 1   63.84  ? 431 ASN B N   1 
ATOM   4478 C  CA  . ASN B 2 261 ? -38.97  -1.162  -23.001 1   69.07  ? 431 ASN B CA  1 
ATOM   4479 C  C   . ASN B 2 261 ? -39.381 -2.215  -21.972 1   70.12  ? 431 ASN B C   1 
ATOM   4480 O  O   . ASN B 2 261 ? -39.587 -3.378  -22.32  1   67.65  ? 431 ASN B O   1 
ATOM   4481 C  CB  . ASN B 2 261 ? -38.471 -1.863  -24.261 1   73.7   ? 431 ASN B CB  1 
ATOM   4482 C  CG  . ASN B 2 261 ? -38.158 -0.934  -25.405 1   74     ? 431 ASN B CG  1 
ATOM   4483 O  OD1 . ASN B 2 261 ? -38.54  0.247   -25.437 1   70.01  ? 431 ASN B OD1 1 
ATOM   4484 N  ND2 . ASN B 2 261 ? -37.446 -1.466  -26.375 1   75.03  ? 431 ASN B ND2 1 
ATOM   4485 N  N   . VAL B 2 262 ? -39.462 -1.798  -20.7   1   70.32  ? 432 VAL B N   1 
ATOM   4486 C  CA  . VAL B 2 262 ? -39.954 -2.654  -19.63  1   72.64  ? 432 VAL B CA  1 
ATOM   4487 C  C   . VAL B 2 262 ? -41.472 -2.376  -19.482 1   85.24  ? 432 VAL B C   1 
ATOM   4488 O  O   . VAL B 2 262 ? -42.198 -2.372  -20.482 1   80.13  ? 432 VAL B O   1 
ATOM   4489 C  CB  . VAL B 2 262 ? -39.165 -2.515  -18.275 1   65.24  ? 432 VAL B CB  1 
ATOM   4490 C  CG1 . VAL B 2 262 ? -37.82  -3.228  -18.342 1   61.7   ? 432 VAL B CG1 1 
ATOM   4491 C  CG2 . VAL B 2 262 ? -38.975 -1.065  -17.837 1   62.4   ? 432 VAL B CG2 1 
ATOM   4492 N  N   . SER C 1 4   ? -15.04  4.552   28.844  1   46.37  ? 0   SER C N   1 
ATOM   4493 C  CA  . SER C 1 4   ? -16.506 4.501   28.76   1   48.76  ? 0   SER C CA  1 
ATOM   4494 C  C   . SER C 1 4   ? -17.05  5.886   28.413  1   45.99  ? 0   SER C C   1 
ATOM   4495 O  O   . SER C 1 4   ? -17.707 6.085   27.391  1   39.4   ? 0   SER C O   1 
ATOM   4496 C  CB  . SER C 1 4   ? -17.127 4.017   30.078  1   49.87  ? 0   SER C CB  1 
ATOM   4497 O  OG  . SER C 1 4   ? -16.792 2.675   30.401  1   52.07  ? 0   SER C OG  1 
ATOM   4498 N  N   . MET C 1 5   ? -16.761 6.833   29.31   1   46.5   ? 1   MET C N   1 
ATOM   4499 C  CA  . MET C 1 5   ? -17.194 8.212   29.187  1   43.54  ? 1   MET C CA  1 
ATOM   4500 C  C   . MET C 1 5   ? -16.086 9.071   28.589  1   37.97  ? 1   MET C C   1 
ATOM   4501 O  O   . MET C 1 5   ? -16.201 10.292  28.586  1   37.96  ? 1   MET C O   1 
ATOM   4502 C  CB  . MET C 1 5   ? -17.561 8.758   30.593  1   46.32  ? 1   MET C CB  1 
ATOM   4503 C  CG  . MET C 1 5   ? -18.739 8.053   31.207  1   45.56  ? 1   MET C CG  1 
ATOM   4504 S  SD  . MET C 1 5   ? -20.168 7.996   30.112  1   52.56  ? 1   MET C SD  1 
ATOM   4505 C  CE  . MET C 1 5   ? -20.446 9.715   29.908  1   54.97  ? 1   MET C CE  1 
ATOM   4506 N  N   . GLU C 1 6   ? -15.016 8.44    28.097  1   34.84  ? 2   GLU C N   1 
ATOM   4507 C  CA  . GLU C 1 6   ? -13.874 9.177   27.584  1   39.29  ? 2   GLU C CA  1 
ATOM   4508 C  C   . GLU C 1 6   ? -14.175 10.025  26.345  1   34.32  ? 2   GLU C C   1 
ATOM   4509 O  O   . GLU C 1 6   ? -13.486 11.007  26.097  1   32.05  ? 2   GLU C O   1 
ATOM   4510 C  CB  . GLU C 1 6   ? -12.73  8.201   27.297  1   46.24  ? 2   GLU C CB  1 
ATOM   4511 C  CG  . GLU C 1 6   ? -11.416 8.868   26.909  1   55.19  ? 2   GLU C CG  1 
ATOM   4512 C  CD  . GLU C 1 6   ? -10.941 9.994   27.813  1   65.37  ? 2   GLU C CD  1 
ATOM   4513 O  OE1 . GLU C 1 6   ? -11.042 9.863   29.057  1   70.81  ? 2   GLU C OE1 1 
ATOM   4514 O  OE2 . GLU C 1 6   ? -10.439 11.004  27.267  1   69.69  ? 2   GLU C OE2 1 
ATOM   4515 N  N   . ASN C 1 7   ? -15.208 9.664   25.572  1   32.67  ? 3   ASN C N   1 
ATOM   4516 C  CA  . ASN C 1 7   ? -15.58  10.468  24.416  1   33.11  ? 3   ASN C CA  1 
ATOM   4517 C  C   . ASN C 1 7   ? -16.575 11.577  24.737  1   31.26  ? 3   ASN C C   1 
ATOM   4518 O  O   . ASN C 1 7   ? -16.895 12.366  23.855  1   33.14  ? 3   ASN C O   1 
ATOM   4519 C  CB  . ASN C 1 7   ? -16.133 9.625   23.277  1   34.6   ? 3   ASN C CB  1 
ATOM   4520 C  CG  . ASN C 1 7   ? -15.116 8.642   22.748  1   35.73  ? 3   ASN C CG  1 
ATOM   4521 O  OD1 . ASN C 1 7   ? -13.906 8.953   22.61   1   30.81  ? 3   ASN C OD1 1 
ATOM   4522 N  ND2 . ASN C 1 7   ? -15.579 7.413   22.517  1   34.58  ? 3   ASN C ND2 1 
ATOM   4523 N  N   . PHE C 1 8   ? -17.019 11.676  25.993  1   28.46  ? 4   PHE C N   1 
ATOM   4524 C  CA  . PHE C 1 8   ? -17.87  12.782  26.395  1   27.57  ? 4   PHE C CA  1 
ATOM   4525 C  C   . PHE C 1 8   ? -17.116 13.834  27.207  1   28.24  ? 4   PHE C C   1 
ATOM   4526 O  O   . PHE C 1 8   ? -16.334 13.507  28.092  1   30.46  ? 4   PHE C O   1 
ATOM   4527 C  CB  . PHE C 1 8   ? -19.076 12.234  27.144  1   26.04  ? 4   PHE C CB  1 
ATOM   4528 C  CG  . PHE C 1 8   ? -20.024 11.465  26.257  1   24.74  ? 4   PHE C CG  1 
ATOM   4529 C  CD1 . PHE C 1 8   ? -20.841 12.12   25.356  1   25.48  ? 4   PHE C CD1 1 
ATOM   4530 C  CD2 . PHE C 1 8   ? -20.085 10.085  26.313  1   25.38  ? 4   PHE C CD2 1 
ATOM   4531 C  CE1 . PHE C 1 8   ? -21.717 11.401  24.53   1   26.85  ? 4   PHE C CE1 1 
ATOM   4532 C  CE2 . PHE C 1 8   ? -20.956 9.368   25.492  1   25.9   ? 4   PHE C CE2 1 
ATOM   4533 C  CZ  . PHE C 1 8   ? -21.768 10.028  24.605  1   27.23  ? 4   PHE C CZ  1 
ATOM   4534 N  N   . GLN C 1 9   ? -17.346 15.103  26.857  1   30.95  ? 5   GLN C N   1 
ATOM   4535 C  CA  . GLN C 1 9   ? -16.782 16.255  27.545  1   30.91  ? 5   GLN C CA  1 
ATOM   4536 C  C   . GLN C 1 9   ? -17.94  17.01   28.191  1   31.17  ? 5   GLN C C   1 
ATOM   4537 O  O   . GLN C 1 9   ? -18.808 17.537  27.496  1   29.56  ? 5   GLN C O   1 
ATOM   4538 C  CB  . GLN C 1 9   ? -16.036 17.141  26.544  1   33.4   ? 5   GLN C CB  1 
ATOM   4539 C  CG  . GLN C 1 9   ? -15.536 18.469  27.085  1   38.32  ? 5   GLN C CG  1 
ATOM   4540 C  CD  . GLN C 1 9   ? -14.478 18.262  28.139  1   43.07  ? 5   GLN C CD  1 
ATOM   4541 O  OE1 . GLN C 1 9   ? -13.364 17.807  27.842  1   44.45  ? 5   GLN C OE1 1 
ATOM   4542 N  NE2 . GLN C 1 9   ? -14.793 18.591  29.393  1   43.18  ? 5   GLN C NE2 1 
ATOM   4543 N  N   . LYS C 1 10  ? -17.96  17.038  29.527  1   34.98  ? 6   LYS C N   1 
ATOM   4544 C  CA  . LYS C 1 10  ? -19.007 17.738  30.255  1   38.19  ? 6   LYS C CA  1 
ATOM   4545 C  C   . LYS C 1 10  ? -18.858 19.232  29.991  1   33.49  ? 6   LYS C C   1 
ATOM   4546 O  O   . LYS C 1 10  ? -17.744 19.729  29.883  1   28.86  ? 6   LYS C O   1 
ATOM   4547 C  CB  . LYS C 1 10  ? -18.958 17.39   31.752  1   44.79  ? 6   LYS C CB  1 
ATOM   4548 C  CG  . LYS C 1 10  ? -19.388 15.931  31.998  1   52.71  ? 6   LYS C CG  1 
ATOM   4549 C  CD  . LYS C 1 10  ? -19.378 15.472  33.47   1   57.25  ? 6   LYS C CD  1 
ATOM   4550 C  CE  . LYS C 1 10  ? -19.805 14.013  33.618  1   57.5   ? 6   LYS C CE  1 
ATOM   4551 N  NZ  . LYS C 1 10  ? -18.761 13.053  33.129  1   55.9   ? 6   LYS C NZ  1 
ATOM   4552 N  N   . VAL C 1 11  ? -19.993 19.919  29.823  1   32.78  ? 7   VAL C N   1 
ATOM   4553 C  CA  . VAL C 1 11  ? -20.01  21.332  29.483  1   34.57  ? 7   VAL C CA  1 
ATOM   4554 C  C   . VAL C 1 11  ? -20.499 22.163  30.669  1   34.8   ? 7   VAL C C   1 
ATOM   4555 O  O   . VAL C 1 11  ? -19.907 23.175  31.008  1   37.41  ? 7   VAL C O   1 
ATOM   4556 C  CB  . VAL C 1 11  ? -20.879 21.562  28.228  1   35.87  ? 7   VAL C CB  1 
ATOM   4557 C  CG1 . VAL C 1 11  ? -21.098 23.049  27.963  1   36.95  ? 7   VAL C CG1 1 
ATOM   4558 C  CG2 . VAL C 1 11  ? -20.277 20.87   27.009  1   36.03  ? 7   VAL C CG2 1 
ATOM   4559 N  N   . GLU C 1 12  ? -21.604 21.741  31.281  1   37.65  ? 8   GLU C N   1 
ATOM   4560 C  CA  . GLU C 1 12  ? -22.183 22.442  32.41   1   39.64  ? 8   GLU C CA  1 
ATOM   4561 C  C   . GLU C 1 12  ? -23.26  21.573  33.052  1   43.64  ? 8   GLU C C   1 
ATOM   4562 O  O   . GLU C 1 12  ? -23.768 20.645  32.429  1   41.63  ? 8   GLU C O   1 
ATOM   4563 C  CB  . GLU C 1 12  ? -22.782 23.781  31.958  1   43.71  ? 8   GLU C CB  1 
ATOM   4564 C  CG  . GLU C 1 12  ? -23.961 23.632  31.015  1   47.84  ? 8   GLU C CG  1 
ATOM   4565 C  CD  . GLU C 1 12  ? -24.503 24.929  30.448  1   47.99  ? 8   GLU C CD  1 
ATOM   4566 O  OE1 . GLU C 1 12  ? -23.753 25.585  29.692  1   48.2   ? 8   GLU C OE1 1 
ATOM   4567 O  OE2 . GLU C 1 12  ? -25.669 25.287  30.746  1   47.44  ? 8   GLU C OE2 1 
ATOM   4568 N  N   . LYS C 1 13  ? -23.598 21.888  34.306  1   52.13  ? 9   LYS C N   1 
ATOM   4569 C  CA  . LYS C 1 13  ? -24.715 21.264  34.996  1   60.61  ? 9   LYS C CA  1 
ATOM   4570 C  C   . LYS C 1 13  ? -26.011 21.855  34.443  1   59.82  ? 9   LYS C C   1 
ATOM   4571 O  O   . LYS C 1 13  ? -26.09  23.06   34.214  1   59.92  ? 9   LYS C O   1 
ATOM   4572 C  CB  . LYS C 1 13  ? -24.595 21.52   36.499  1   69.66  ? 9   LYS C CB  1 
ATOM   4573 C  CG  . LYS C 1 13  ? -25.691 20.858  37.323  1   82.58  ? 9   LYS C CG  1 
ATOM   4574 C  CD  . LYS C 1 13  ? -25.445 20.904  38.841  1   90.24  ? 9   LYS C CD  1 
ATOM   4575 C  CE  . LYS C 1 13  ? -24.029 20.543  39.298  1   94.25  ? 9   LYS C CE  1 
ATOM   4576 N  NZ  . LYS C 1 13  ? -23.43  19.359  38.602  1   95.14  ? 9   LYS C NZ  1 
ATOM   4577 N  N   . ILE C 1 14  ? -27.019 21.012  34.194  1   55.36  ? 10  ILE C N   1 
ATOM   4578 C  CA  . ILE C 1 14  ? -28.278 21.52   33.671  1   55.99  ? 10  ILE C CA  1 
ATOM   4579 C  C   . ILE C 1 14  ? -29.459 21.225  34.587  1   59.88  ? 10  ILE C C   1 
ATOM   4580 O  O   . ILE C 1 14  ? -30.546 21.751  34.372  1   65.06  ? 10  ILE C O   1 
ATOM   4581 C  CB  . ILE C 1 14  ? -28.548 21.037  32.22   1   54.41  ? 10  ILE C CB  1 
ATOM   4582 C  CG1 . ILE C 1 14  ? -28.659 19.521  32.093  1   53.38  ? 10  ILE C CG1 1 
ATOM   4583 C  CG2 . ILE C 1 14  ? -27.479 21.584  31.281  1   59.99  ? 10  ILE C CG2 1 
ATOM   4584 C  CD1 . ILE C 1 14  ? -28.874 19.057  30.644  1   51.1   ? 10  ILE C CD1 1 
ATOM   4585 N  N   . GLY C 1 15  ? -29.24  20.418  35.625  1   62.19  ? 11  GLY C N   1 
ATOM   4586 C  CA  . GLY C 1 15  ? -30.29  20.177  36.592  1   64.42  ? 11  GLY C CA  1 
ATOM   4587 C  C   . GLY C 1 15  ? -30.005 19.022  37.538  1   68.16  ? 11  GLY C C   1 
ATOM   4588 O  O   . GLY C 1 15  ? -28.92  18.453  37.523  1   64.08  ? 11  GLY C O   1 
ATOM   4589 N  N   . GLU C 1 16  ? -31.015 18.731  38.362  1   78.26  ? 12  GLU C N   1 
ATOM   4590 C  CA  . GLU C 1 16  ? -30.999 17.657  39.334  1   79.82  ? 12  GLU C CA  1 
ATOM   4591 C  C   . GLU C 1 16  ? -32.239 16.815  39.063  1   81.89  ? 12  GLU C C   1 
ATOM   4592 O  O   . GLU C 1 16  ? -33.096 17.195  38.266  1   83.61  ? 12  GLU C O   1 
ATOM   4593 C  CB  . GLU C 1 16  ? -31.017 18.238  40.761  1   83.46  ? 12  GLU C CB  1 
ATOM   4594 C  CG  . GLU C 1 16  ? -29.706 18.851  41.221  1   82.98  ? 12  GLU C CG  1 
ATOM   4595 C  CD  . GLU C 1 16  ? -28.696 17.868  41.786  1   85.63  ? 12  GLU C CD  1 
ATOM   4596 O  OE1 . GLU C 1 16  ? -28.922 16.64   41.699  1   86.16  ? 12  GLU C OE1 1 
ATOM   4597 O  OE2 . GLU C 1 16  ? -27.677 18.336  42.339  1   81.13  ? 12  GLU C OE2 1 
ATOM   4598 N  N   . GLY C 1 17  ? -32.298 15.665  39.731  1   89.85  ? 13  GLY C N   1 
ATOM   4599 C  CA  . GLY C 1 17  ? -33.389 14.716  39.59   1   98.37  ? 13  GLY C CA  1 
ATOM   4600 C  C   . GLY C 1 17  ? -33.232 13.621  40.64   1   109.52 ? 13  GLY C C   1 
ATOM   4601 O  O   . GLY C 1 17  ? -32.304 13.669  41.449  1   106.75 ? 13  GLY C O   1 
ATOM   4602 N  N   . THR C 1 18  ? -34.146 12.647  40.617  1   115.63 ? 14  THR C N   1 
ATOM   4603 C  CA  . THR C 1 18  ? -34.176 11.579  41.606  1   115.67 ? 14  THR C CA  1 
ATOM   4604 C  C   . THR C 1 18  ? -32.848 10.829  41.741  1   113.5  ? 14  THR C C   1 
ATOM   4605 O  O   . THR C 1 18  ? -32.381 10.59   42.859  1   100.47 ? 14  THR C O   1 
ATOM   4606 C  CB  . THR C 1 18  ? -35.329 10.617  41.266  1   107.21 ? 14  THR C CB  1 
ATOM   4607 O  OG1 . THR C 1 18  ? -35.285 10.327  39.87   1   108.08 ? 14  THR C OG1 1 
ATOM   4608 C  CG2 . THR C 1 18  ? -36.693 11.19   41.629  1   101.45 ? 14  THR C CG2 1 
ATOM   4609 N  N   . TYR C 1 19  ? -32.237 10.503  40.591  1   103.82 ? 15  TYR C N   1 
ATOM   4610 C  CA  . TYR C 1 19  ? -31.053 9.652   40.545  1   96.55  ? 15  TYR C CA  1 
ATOM   4611 C  C   . TYR C 1 19  ? -29.784 10.371  40.987  1   92.17  ? 15  TYR C C   1 
ATOM   4612 O  O   . TYR C 1 19  ? -28.934 9.804   41.674  1   82.54  ? 15  TYR C O   1 
ATOM   4613 C  CB  . TYR C 1 19  ? -30.753 9.17    39.134  1   92.13  ? 15  TYR C CB  1 
ATOM   4614 C  CG  . TYR C 1 19  ? -31.936 8.657   38.35   1   88.09  ? 15  TYR C CG  1 
ATOM   4615 C  CD1 . TYR C 1 19  ? -32.554 7.46    38.687  1   78.37  ? 15  TYR C CD1 1 
ATOM   4616 C  CD2 . TYR C 1 19  ? -32.432 9.365   37.265  1   85     ? 15  TYR C CD2 1 
ATOM   4617 C  CE1 . TYR C 1 19  ? -33.635 6.976   37.956  1   71.25  ? 15  TYR C CE1 1 
ATOM   4618 C  CE2 . TYR C 1 19  ? -33.51  8.893   36.528  1   82.09  ? 15  TYR C CE2 1 
ATOM   4619 C  CZ  . TYR C 1 19  ? -34.11  7.696   36.874  1   72.68  ? 15  TYR C CZ  1 
ATOM   4620 O  OH  . TYR C 1 19  ? -35.171 7.248   36.131  1   61.76  ? 15  TYR C OH  1 
ATOM   4621 N  N   . GLY C 1 20  ? -29.647 11.602  40.492  1   84.25  ? 16  GLY C N   1 
ATOM   4622 C  CA  . GLY C 1 20  ? -28.444 12.387  40.688  1   77.53  ? 16  GLY C CA  1 
ATOM   4623 C  C   . GLY C 1 20  ? -28.5   13.72   39.948  1   74.96  ? 16  GLY C C   1 
ATOM   4624 O  O   . GLY C 1 20  ? -29.533 14.386  39.941  1   72.33  ? 16  GLY C O   1 
ATOM   4625 N  N   . VAL C 1 21  ? -27.378 14.081  39.314  1   73.12  ? 17  VAL C N   1 
ATOM   4626 C  CA  . VAL C 1 21  ? -27.255 15.344  38.609  1   64.68  ? 17  VAL C CA  1 
ATOM   4627 C  C   . VAL C 1 21  ? -27.299 15.083  37.103  1   60.81  ? 17  VAL C C   1 
ATOM   4628 O  O   . VAL C 1 21  ? -27.005 13.973  36.654  1   58.31  ? 17  VAL C O   1 
ATOM   4629 C  CB  . VAL C 1 21  ? -25.984 16.091  39.097  1   66.31  ? 17  VAL C CB  1 
ATOM   4630 C  CG1 . VAL C 1 21  ? -24.693 15.424  38.626  1   69.72  ? 17  VAL C CG1 1 
ATOM   4631 C  CG2 . VAL C 1 21  ? -26.027 17.556  38.699  1   66.15  ? 17  VAL C CG2 1 
ATOM   4632 N  N   . VAL C 1 22  ? -27.733 16.099  36.344  1   53.26  ? 18  VAL C N   1 
ATOM   4633 C  CA  . VAL C 1 22  ? -27.782 16.028  34.893  1   46.32  ? 18  VAL C CA  1 
ATOM   4634 C  C   . VAL C 1 22  ? -26.795 17.045  34.328  1   42.09  ? 18  VAL C C   1 
ATOM   4635 O  O   . VAL C 1 22  ? -26.809 18.216  34.718  1   39.21  ? 18  VAL C O   1 
ATOM   4636 C  CB  . VAL C 1 22  ? -29.216 16.257  34.362  1   45.42  ? 18  VAL C CB  1 
ATOM   4637 C  CG1 . VAL C 1 22  ? -29.3   16.032  32.855  1   44.44  ? 18  VAL C CG1 1 
ATOM   4638 C  CG2 . VAL C 1 22  ? -30.213 15.363  35.086  1   46.82  ? 18  VAL C CG2 1 
ATOM   4639 N  N   . TYR C 1 23  ? -25.934 16.575  33.415  1   40.94  ? 19  TYR C N   1 
ATOM   4640 C  CA  . TYR C 1 23  ? -24.942 17.416  32.764  1   39.68  ? 19  TYR C CA  1 
ATOM   4641 C  C   . TYR C 1 23  ? -25.264 17.532  31.28   1   34.36  ? 19  TYR C C   1 
ATOM   4642 O  O   . TYR C 1 23  ? -25.728 16.574  30.66   1   31.9   ? 19  TYR C O   1 
ATOM   4643 C  CB  . TYR C 1 23  ? -23.528 16.853  32.855  1   46.7   ? 19  TYR C CB  1 
ATOM   4644 C  CG  . TYR C 1 23  ? -22.994 16.562  34.235  1   58.56  ? 19  TYR C CG  1 
ATOM   4645 C  CD1 . TYR C 1 23  ? -22.364 17.55   34.983  1   62.8   ? 19  TYR C CD1 1 
ATOM   4646 C  CD2 . TYR C 1 23  ? -23.099 15.289  34.787  1   70.74  ? 19  TYR C CD2 1 
ATOM   4647 C  CE1 . TYR C 1 23  ? -21.853 17.28   36.249  1   68.82  ? 19  TYR C CE1 1 
ATOM   4648 C  CE2 . TYR C 1 23  ? -22.59  15.006  36.049  1   76.55  ? 19  TYR C CE2 1 
ATOM   4649 C  CZ  . TYR C 1 23  ? -21.97  16.007  36.78   1   76.6   ? 19  TYR C CZ  1 
ATOM   4650 O  OH  . TYR C 1 23  ? -21.475 15.729  38.031  1   88.96  ? 19  TYR C OH  1 
ATOM   4651 N  N   . LYS C 1 24  ? -25.004 18.719  30.724  1   30.93  ? 20  LYS C N   1 
ATOM   4652 C  CA  . LYS C 1 24  ? -24.924 18.893  29.288  1   28.13  ? 20  LYS C CA  1 
ATOM   4653 C  C   . LYS C 1 24  ? -23.513 18.467  28.91   1   27.91  ? 20  LYS C C   1 
ATOM   4654 O  O   . LYS C 1 24  ? -22.556 18.837  29.587  1   26.23  ? 20  LYS C O   1 
ATOM   4655 C  CB  . LYS C 1 24  ? -25.186 20.329  28.893  1   27.75  ? 20  LYS C CB  1 
ATOM   4656 C  CG  . LYS C 1 24  ? -24.952 20.646  27.428  1   28.98  ? 20  LYS C CG  1 
ATOM   4657 C  CD  . LYS C 1 24  ? -25.231 22.107  27.156  1   29.28  ? 20  LYS C CD  1 
ATOM   4658 C  CE  . LYS C 1 24  ? -25.102 22.431  25.718  1   31.07  ? 20  LYS C CE  1 
ATOM   4659 N  NZ  . LYS C 1 24  ? -25.268 23.874  25.463  1   34.2   ? 20  LYS C NZ  1 
ATOM   4660 N  N   . ALA C 1 25  ? -23.397 17.671  27.844  1   27.11  ? 21  ALA C N   1 
ATOM   4661 C  CA  . ALA C 1 25  ? -22.104 17.174  27.409  1   28.34  ? 21  ALA C CA  1 
ATOM   4662 C  C   . ALA C 1 25  ? -22.009 17.138  25.888  1   27.16  ? 21  ALA C C   1 
ATOM   4663 O  O   . ALA C 1 25  ? -23.015 17.221  25.187  1   25.23  ? 21  ALA C O   1 
ATOM   4664 C  CB  . ALA C 1 25  ? -21.852 15.789  27.997  1   29.34  ? 21  ALA C CB  1 
ATOM   4665 N  N   . ARG C 1 26  ? -20.775 17.024  25.401  1   26.89  ? 22  ARG C N   1 
ATOM   4666 C  CA  . ARG C 1 26  ? -20.486 17.038  23.98   1   30.59  ? 22  ARG C CA  1 
ATOM   4667 C  C   . ARG C 1 26  ? -19.719 15.764  23.643  1   28.54  ? 22  ARG C C   1 
ATOM   4668 O  O   . ARG C 1 26  ? -18.754 15.435  24.327  1   25.45  ? 22  ARG C O   1 
ATOM   4669 C  CB  . ARG C 1 26  ? -19.644 18.283  23.641  1   35.62  ? 22  ARG C CB  1 
ATOM   4670 C  CG  . ARG C 1 26  ? -19.633 18.662  22.18   1   42.24  ? 22  ARG C CG  1 
ATOM   4671 C  CD  . ARG C 1 26  ? -18.684 19.816  21.936  1   45.79  ? 22  ARG C CD  1 
ATOM   4672 N  NE  . ARG C 1 26  ? -17.299 19.367  22.052  1   54.79  ? 22  ARG C NE  1 
ATOM   4673 C  CZ  . ARG C 1 26  ? -16.468 19.695  23.036  1   54.71  ? 22  ARG C CZ  1 
ATOM   4674 N  NH1 . ARG C 1 26  ? -16.794 20.605  23.941  1   55     ? 22  ARG C NH1 1 
ATOM   4675 N  NH2 . ARG C 1 26  ? -15.281 19.095  23.115  1   49.03  ? 22  ARG C NH2 1 
ATOM   4676 N  N   . ASN C 1 27  ? -20.168 15.045  22.605  1   25.5   ? 23  ASN C N   1 
ATOM   4677 C  CA  . ASN C 1 27  ? -19.419 13.922  22.07   1   23.96  ? 23  ASN C CA  1 
ATOM   4678 C  C   . ASN C 1 27  ? -18.225 14.478  21.304  1   23.23  ? 23  ASN C C   1 
ATOM   4679 O  O   . ASN C 1 27  ? -18.415 15.172  20.318  1   24.41  ? 23  ASN C O   1 
ATOM   4680 C  CB  . ASN C 1 27  ? -20.294 13.052  21.16   1   23.76  ? 23  ASN C CB  1 
ATOM   4681 C  CG  . ASN C 1 27  ? -19.577 11.811  20.645  1   23.02  ? 23  ASN C CG  1 
ATOM   4682 O  OD1 . ASN C 1 27  ? -18.402 11.831  20.221  1   20.5   ? 23  ASN C OD1 1 
ATOM   4683 N  ND2 . ASN C 1 27  ? -20.281 10.708  20.673  1   23.74  ? 23  ASN C ND2 1 
ATOM   4684 N  N   . LYS C 1 28  ? -17.004 14.164  21.753  1   24.68  ? 24  LYS C N   1 
ATOM   4685 C  CA  . LYS C 1 28  ? -15.803 14.768  21.195  1   27.84  ? 24  LYS C CA  1 
ATOM   4686 C  C   . LYS C 1 28  ? -15.488 14.321  19.77   1   27.81  ? 24  LYS C C   1 
ATOM   4687 O  O   . LYS C 1 28  ? -14.783 15.025  19.039  1   30.26  ? 24  LYS C O   1 
ATOM   4688 C  CB  . LYS C 1 28  ? -14.579 14.434  22.054  1   32.25  ? 24  LYS C CB  1 
ATOM   4689 C  CG  . LYS C 1 28  ? -14.628 14.963  23.474  1   37.14  ? 24  LYS C CG  1 
ATOM   4690 C  CD  . LYS C 1 28  ? -13.385 14.549  24.264  1   40.05  ? 24  LYS C CD  1 
ATOM   4691 C  CE  . LYS C 1 28  ? -13.725 14.134  25.673  1   42.74  ? 24  LYS C CE  1 
ATOM   4692 N  NZ  . LYS C 1 28  ? -12.509 13.999  26.512  1   44.07  ? 24  LYS C NZ  1 
ATOM   4693 N  N   . LEU C 1 29  ? -15.99  13.138  19.39   1   24.6   ? 25  LEU C N   1 
ATOM   4694 C  CA  . LEU C 1 29  ? -15.726 12.593  18.07   1   22.81  ? 25  LEU C CA  1 
ATOM   4695 C  C   . LEU C 1 29  ? -16.781 12.984  17.036  1   22.58  ? 25  LEU C C   1 
ATOM   4696 O  O   . LEU C 1 29  ? -16.422 13.284  15.903  1   22.87  ? 25  LEU C O   1 
ATOM   4697 C  CB  . LEU C 1 29  ? -15.591 11.078  18.172  1   20.68  ? 25  LEU C CB  1 
ATOM   4698 C  CG  . LEU C 1 29  ? -14.323 10.62   18.883  1   19.19  ? 25  LEU C CG  1 
ATOM   4699 C  CD1 . LEU C 1 29  ? -14.304 9.115   19.057  1   18.84  ? 25  LEU C CD1 1 
ATOM   4700 C  CD2 . LEU C 1 29  ? -13.102 11.089  18.146  1   18.88  ? 25  LEU C CD2 1 
ATOM   4701 N  N   . THR C 1 30  ? -18.065 12.974  17.424  1   22.38  ? 26  THR C N   1 
ATOM   4702 C  CA  . THR C 1 30  ? -19.149 13.285  16.503  1   21.92  ? 26  THR C CA  1 
ATOM   4703 C  C   . THR C 1 30  ? -19.662 14.726  16.57   1   24.07  ? 26  THR C C   1 
ATOM   4704 O  O   . THR C 1 30  ? -20.339 15.176  15.649  1   21.7   ? 26  THR C O   1 
ATOM   4705 C  CB  . THR C 1 30  ? -20.343 12.355  16.712  1   21.36  ? 26  THR C CB  1 
ATOM   4706 O  OG1 . THR C 1 30  ? -20.935 12.645  17.945  1   20.56  ? 26  THR C OG1 1 
ATOM   4707 C  CG2 . THR C 1 30  ? -19.966 10.879  16.672  1   22.53  ? 26  THR C CG2 1 
ATOM   4708 N  N   . GLY C 1 31  ? -19.361 15.434  17.674  1   24.63  ? 27  GLY C N   1 
ATOM   4709 C  CA  . GLY C 1 31  ? -19.885 16.769  17.922  1   23.59  ? 27  GLY C CA  1 
ATOM   4710 C  C   . GLY C 1 31  ? -21.291 16.811  18.53   1   25.78  ? 27  GLY C C   1 
ATOM   4711 O  O   . GLY C 1 31  ? -21.819 17.886  18.804  1   28.38  ? 27  GLY C O   1 
ATOM   4712 N  N   . GLU C 1 32  ? -21.918 15.648  18.736  1   26.3   ? 28  GLU C N   1 
ATOM   4713 C  CA  . GLU C 1 32  ? -23.274 15.606  19.268  1   27.13  ? 28  GLU C CA  1 
ATOM   4714 C  C   . GLU C 1 32  ? -23.339 16.138  20.703  1   28.11  ? 28  GLU C C   1 
ATOM   4715 O  O   . GLU C 1 32  ? -22.556 15.736  21.562  1   28.85  ? 28  GLU C O   1 
ATOM   4716 C  CB  . GLU C 1 32  ? -23.812 14.179  19.246  1   26.7   ? 28  GLU C CB  1 
ATOM   4717 C  CG  . GLU C 1 32  ? -25.297 14.07   19.573  1   27.38  ? 28  GLU C CG  1 
ATOM   4718 C  CD  . GLU C 1 32  ? -25.806 12.628  19.629  1   29.21  ? 28  GLU C CD  1 
ATOM   4719 O  OE1 . GLU C 1 32  ? -25.004 11.706  19.907  1   28.05  ? 28  GLU C OE1 1 
ATOM   4720 O  OE2 . GLU C 1 32  ? -27.009 12.419  19.37   1   33.68  ? 28  GLU C OE2 1 
ATOM   4721 N  N   . VAL C 1 33  ? -24.286 17.048  20.945  1   27.2   ? 29  VAL C N   1 
ATOM   4722 C  CA  . VAL C 1 33  ? -24.561 17.567  22.271  1   24.1   ? 29  VAL C CA  1 
ATOM   4723 C  C   . VAL C 1 33  ? -25.632 16.693  22.919  1   23.09  ? 29  VAL C C   1 
ATOM   4724 O  O   . VAL C 1 33  ? -26.636 16.374  22.281  1   22.81  ? 29  VAL C O   1 
ATOM   4725 C  CB  . VAL C 1 33  ? -24.998 19.039  22.175  1   24.33  ? 29  VAL C CB  1 
ATOM   4726 C  CG1 . VAL C 1 33  ? -25.361 19.589  23.547  1   24.32  ? 29  VAL C CG1 1 
ATOM   4727 C  CG2 . VAL C 1 33  ? -23.924 19.889  21.511  1   23.45  ? 29  VAL C CG2 1 
ATOM   4728 N  N   . VAL C 1 34  ? -25.409 16.321  24.185  1   20.01  ? 30  VAL C N   1 
ATOM   4729 C  CA  . VAL C 1 34  ? -26.251 15.353  24.869  1   19.72  ? 30  VAL C CA  1 
ATOM   4730 C  C   . VAL C 1 34  ? -26.517 15.796  26.304  1   21.09  ? 30  VAL C C   1 
ATOM   4731 O  O   . VAL C 1 34  ? -25.845 16.68   26.821  1   24.41  ? 30  VAL C O   1 
ATOM   4732 C  CB  . VAL C 1 34  ? -25.611 13.92   24.862  1   17.82  ? 30  VAL C CB  1 
ATOM   4733 C  CG1 . VAL C 1 34  ? -25.354 13.434  23.456  1   17.49  ? 30  VAL C CG1 1 
ATOM   4734 C  CG2 . VAL C 1 34  ? -24.33  13.876  25.683  1   18.55  ? 30  VAL C CG2 1 
ATOM   4735 N  N   . ALA C 1 35  ? -27.49  15.155  26.951  1   22.57  ? 31  ALA C N   1 
ATOM   4736 C  CA  . ALA C 1 35  ? -27.636 15.236  28.392  1   23.86  ? 31  ALA C CA  1 
ATOM   4737 C  C   . ALA C 1 35  ? -27.254 13.888  28.993  1   24.84  ? 31  ALA C C   1 
ATOM   4738 O  O   . ALA C 1 35  ? -27.715 12.85   28.523  1   25     ? 31  ALA C O   1 
ATOM   4739 C  CB  . ALA C 1 35  ? -29.054 15.607  28.772  1   23.78  ? 31  ALA C CB  1 
ATOM   4740 N  N   . LEU C 1 36  ? -26.377 13.937  29.999  1   28.55  ? 32  LEU C N   1 
ATOM   4741 C  CA  . LEU C 1 36  ? -25.929 12.767  30.731  1   29.78  ? 32  LEU C CA  1 
ATOM   4742 C  C   . LEU C 1 36  ? -26.61  12.736  32.091  1   33.17  ? 32  LEU C C   1 
ATOM   4743 O  O   . LEU C 1 36  ? -26.486 13.675  32.885  1   35.99  ? 32  LEU C O   1 
ATOM   4744 C  CB  . LEU C 1 36  ? -24.41  12.806  30.939  1   30.13  ? 32  LEU C CB  1 
ATOM   4745 C  CG  . LEU C 1 36  ? -23.574 12.767  29.675  1   30.52  ? 32  LEU C CG  1 
ATOM   4746 C  CD1 . LEU C 1 36  ? -22.114 12.791  30.005  1   31.96  ? 32  LEU C CD1 1 
ATOM   4747 C  CD2 . LEU C 1 36  ? -23.884 11.539  28.82   1   32.2   ? 32  LEU C CD2 1 
ATOM   4748 N  N   . LYS C 1 37  ? -27.33  11.646  32.347  1   35.27  ? 33  LYS C N   1 
ATOM   4749 C  CA  . LYS C 1 37  ? -27.95  11.413  33.641  1   35.28  ? 33  LYS C CA  1 
ATOM   4750 C  C   . LYS C 1 37  ? -27.107 10.367  34.371  1   34.77  ? 33  LYS C C   1 
ATOM   4751 O  O   . LYS C 1 37  ? -27.083 9.214   33.968  1   36.92  ? 33  LYS C O   1 
ATOM   4752 C  CB  . LYS C 1 37  ? -29.388 10.948  33.396  1   40.93  ? 33  LYS C CB  1 
ATOM   4753 C  CG  . LYS C 1 37  ? -30.45  11.354  34.39   1   44.81  ? 33  LYS C CG  1 
ATOM   4754 C  CD  . LYS C 1 37  ? -31.833 10.82   33.938  1   47.92  ? 33  LYS C CD  1 
ATOM   4755 C  CE  . LYS C 1 37  ? -32.996 11.649  34.421  1   56.98  ? 33  LYS C CE  1 
ATOM   4756 N  NZ  . LYS C 1 37  ? -34.271 11.246  33.767  1   54.72  ? 33  LYS C NZ  1 
ATOM   4757 N  N   . LYS C 1 38  ? -26.363 10.779  35.402  1   38.28  ? 34  LYS C N   1 
ATOM   4758 C  CA  . LYS C 1 38  ? -25.575 9.859   36.209  1   41.79  ? 34  LYS C CA  1 
ATOM   4759 C  C   . LYS C 1 38  ? -26.464 9.232   37.281  1   41.32  ? 34  LYS C C   1 
ATOM   4760 O  O   . LYS C 1 38  ? -27.184 9.953   37.968  1   44.52  ? 34  LYS C O   1 
ATOM   4761 C  CB  . LYS C 1 38  ? -24.402 10.594  36.859  1   45.57  ? 34  LYS C CB  1 
ATOM   4762 C  CG  . LYS C 1 38  ? -23.435 9.704   37.622  1   53.43  ? 34  LYS C CG  1 
ATOM   4763 C  CD  . LYS C 1 38  ? -22.155 10.457  38.035  1   61.23  ? 34  LYS C CD  1 
ATOM   4764 C  CE  . LYS C 1 38  ? -22.306 11.252  39.299  1   65.05  ? 34  LYS C CE  1 
ATOM   4765 N  NZ  . LYS C 1 38  ? -22.135 10.385  40.499  1   69.77  ? 34  LYS C NZ  1 
ATOM   4766 N  N   . ILE C 1 39  ? -26.428 7.894   37.389  1   39.37  ? 35  ILE C N   1 
ATOM   4767 C  CA  . ILE C 1 39  ? -27.235 7.161   38.354  1   39.16  ? 35  ILE C CA  1 
ATOM   4768 C  C   . ILE C 1 39  ? -26.283 6.323   39.195  1   40.13  ? 35  ILE C C   1 
ATOM   4769 O  O   . ILE C 1 39  ? -25.649 5.411   38.669  1   41.14  ? 35  ILE C O   1 
ATOM   4770 C  CB  . ILE C 1 39  ? -28.321 6.259   37.706  1   39.86  ? 35  ILE C CB  1 
ATOM   4771 C  CG1 . ILE C 1 39  ? -29.223 7.059   36.742  1   42.9   ? 35  ILE C CG1 1 
ATOM   4772 C  CG2 . ILE C 1 39  ? -29.135 5.528   38.774  1   40.17  ? 35  ILE C CG2 1 
ATOM   4773 C  CD1 . ILE C 1 39  ? -30.392 6.326   36.197  1   45.58  ? 35  ILE C CD1 1 
ATOM   4774 N  N   . ARG C 1 40  ? -26.209 6.635   40.496  1   42.32  ? 36  ARG C N   1 
ATOM   4775 C  CA  . ARG C 1 40  ? -25.399 5.885   41.439  1   44.39  ? 36  ARG C CA  1 
ATOM   4776 C  C   . ARG C 1 40  ? -26.028 4.517   41.707  1   40.5   ? 36  ARG C C   1 
ATOM   4777 O  O   . ARG C 1 40  ? -27.231 4.414   41.963  1   34.94  ? 36  ARG C O   1 
ATOM   4778 C  CB  . ARG C 1 40  ? -25.248 6.699   42.738  1   55.35  ? 36  ARG C CB  1 
ATOM   4779 C  CG  . ARG C 1 40  ? -24.333 6.091   43.826  1   69.17  ? 36  ARG C CG  1 
ATOM   4780 C  CD  . ARG C 1 40  ? -22.877 5.886   43.397  1   77.96  ? 36  ARG C CD  1 
ATOM   4781 N  NE  . ARG C 1 40  ? -22.173 7.146   43.177  1   89.96  ? 36  ARG C NE  1 
ATOM   4782 C  CZ  . ARG C 1 40  ? -20.864 7.256   42.976  1   95.59  ? 36  ARG C CZ  1 
ATOM   4783 N  NH1 . ARG C 1 40  ? -20.061 6.206   43.049  1   94.29  ? 36  ARG C NH1 1 
ATOM   4784 N  NH2 . ARG C 1 40  ? -20.348 8.453   42.707  1   96.76  ? 36  ARG C NH2 1 
ATOM   4785 N  N   . LEU C 1 41  ? -25.197 3.473   41.606  1   35.75  ? 37  LEU C N   1 
ATOM   4786 C  CA  . LEU C 1 41  ? -25.637 2.122   41.887  1   35.96  ? 37  LEU C CA  1 
ATOM   4787 C  C   . LEU C 1 41  ? -25.217 1.798   43.318  1   34.97  ? 37  LEU C C   1 
ATOM   4788 O  O   . LEU C 1 41  ? -24.06  1.975   43.701  1   33.89  ? 37  LEU C O   1 
ATOM   4789 C  CB  . LEU C 1 41  ? -25.072 1.127   40.875  1   34.75  ? 37  LEU C CB  1 
ATOM   4790 C  CG  . LEU C 1 41  ? -25.364 1.439   39.426  1   34.82  ? 37  LEU C CG  1 
ATOM   4791 C  CD1 . LEU C 1 41  ? -24.874 0.315   38.523  1   33.24  ? 37  LEU C CD1 1 
ATOM   4792 C  CD2 . LEU C 1 41  ? -26.847 1.702   39.2    1   36.93  ? 37  LEU C CD2 1 
ATOM   4793 N  N   . ASP C 1 42  ? -26.212 1.403   44.114  1   33.56  ? 38  ASP C N   1 
ATOM   4794 C  CA  . ASP C 1 42  ? -26.006 1.014   45.499  1   34.7   ? 38  ASP C CA  1 
ATOM   4795 C  C   . ASP C 1 42  ? -25.481 -0.421  45.529  1   28.59  ? 38  ASP C C   1 
ATOM   4796 O  O   . ASP C 1 42  ? -26.22  -1.355  45.844  1   25.21  ? 38  ASP C O   1 
ATOM   4797 C  CB  . ASP C 1 42  ? -27.327 1.187   46.299  1   37.53  ? 38  ASP C CB  1 
ATOM   4798 C  CG  . ASP C 1 42  ? -27.892 2.606   46.28   1   40.84  ? 38  ASP C CG  1 
ATOM   4799 O  OD1 . ASP C 1 42  ? -27.16  3.54    46.657  1   46.54  ? 38  ASP C OD1 1 
ATOM   4800 O  OD2 . ASP C 1 42  ? -29.069 2.776   45.895  1   43.02  ? 38  ASP C OD2 1 
ATOM   4801 N  N   . THR C 1 43  ? -24.188 -0.582  45.212  1   23.68  ? 39  THR C N   1 
ATOM   4802 C  CA  . THR C 1 43  ? -23.632 -1.893  44.913  1   23.28  ? 39  THR C CA  1 
ATOM   4803 C  C   . THR C 1 43  ? -23.394 -2.821  46.096  1   22.19  ? 39  THR C C   1 
ATOM   4804 O  O   . THR C 1 43  ? -23.07  -3.979  45.882  1   23.51  ? 39  THR C O   1 
ATOM   4805 C  CB  . THR C 1 43  ? -22.29  -1.773  44.141  1   24.8   ? 39  THR C CB  1 
ATOM   4806 O  OG1 . THR C 1 43  ? -21.308 -1.157  44.969  1   22.62  ? 39  THR C OG1 1 
ATOM   4807 C  CG2 . THR C 1 43  ? -22.445 -1.004  42.813  1   24.33  ? 39  THR C CG2 1 
ATOM   4808 N  N   . GLU C 1 44  ? -23.518 -2.319  47.334  1   22.25  ? 40  GLU C N   1 
ATOM   4809 C  CA  . GLU C 1 44  ? -23.493 -3.179  48.508  1   21.15  ? 40  GLU C CA  1 
ATOM   4810 C  C   . GLU C 1 44  ? -24.85  -3.308  49.188  1   19.94  ? 40  GLU C C   1 
ATOM   4811 O  O   . GLU C 1 44  ? -24.971 -4.064  50.15   1   21.07  ? 40  GLU C O   1 
ATOM   4812 C  CB  . GLU C 1 44  ? -22.502 -2.663  49.555  1   22.05  ? 40  GLU C CB  1 
ATOM   4813 C  CG  . GLU C 1 44  ? -21.057 -2.693  49.108  1   23     ? 40  GLU C CG  1 
ATOM   4814 C  CD  . GLU C 1 44  ? -20.721 -1.688  48.027  1   22.51  ? 40  GLU C CD  1 
ATOM   4815 O  OE1 . GLU C 1 44  ? -21.006 -0.488  48.227  1   23.91  ? 40  GLU C OE1 1 
ATOM   4816 O  OE2 . GLU C 1 44  ? -20.2   -2.102  46.97   1   22.22  ? 40  GLU C OE2 1 
ATOM   4817 N  N   . THR C 1 45  ? -25.852 -2.558  48.713  1   18.62  ? 41  THR C N   1 
ATOM   4818 C  CA  . THR C 1 45  ? -27.129 -2.482  49.41   1   19.69  ? 41  THR C CA  1 
ATOM   4819 C  C   . THR C 1 45  ? -28.344 -2.793  48.544  1   19.31  ? 41  THR C C   1 
ATOM   4820 O  O   . THR C 1 45  ? -28.918 -3.862  48.699  1   19.6   ? 41  THR C O   1 
ATOM   4821 C  CB  . THR C 1 45  ? -27.284 -1.127  50.161  1   19.05  ? 41  THR C CB  1 
ATOM   4822 O  OG1 . THR C 1 45  ? -27.157 -0.025  49.274  1   16.99  ? 41  THR C OG1 1 
ATOM   4823 C  CG2 . THR C 1 45  ? -26.256 -0.991  51.253  1   19.52  ? 41  THR C CG2 1 
ATOM   4824 N  N   . GLU C 1 46  ? -28.794 -1.861  47.701  1   21.17  ? 42  GLU C N   1 
ATOM   4825 C  CA  . GLU C 1 46  ? -30.074 -2.048  47.031  1   24.08  ? 42  GLU C CA  1 
ATOM   4826 C  C   . GLU C 1 46  ? -29.97  -2.165  45.513  1   21.81  ? 42  GLU C C   1 
ATOM   4827 O  O   . GLU C 1 46  ? -30.974 -2.426  44.872  1   21.03  ? 42  GLU C O   1 
ATOM   4828 C  CB  . GLU C 1 46  ? -31.104 -0.951  47.434  1   26.74  ? 42  GLU C CB  1 
ATOM   4829 C  CG  . GLU C 1 46  ? -31.555 -1.016  48.902  1   32.45  ? 42  GLU C CG  1 
ATOM   4830 C  CD  . GLU C 1 46  ? -32.087 -2.334  49.486  1   37.4   ? 42  GLU C CD  1 
ATOM   4831 O  OE1 . GLU C 1 46  ? -33.134 -2.863  49.037  1   36.97  ? 42  GLU C OE1 1 
ATOM   4832 O  OE2 . GLU C 1 46  ? -31.426 -2.838  50.424  1   43.96  ? 42  GLU C OE2 1 
ATOM   4833 N  N   . GLY C 1 47  ? -28.765 -2.025  44.951  1   20.32  ? 43  GLY C N   1 
ATOM   4834 C  CA  . GLY C 1 47  ? -28.55  -2.303  43.544  1   19.09  ? 43  GLY C CA  1 
ATOM   4835 C  C   . GLY C 1 47  ? -29.141 -1.215  42.66   1   21.74  ? 43  GLY C C   1 
ATOM   4836 O  O   . GLY C 1 47  ? -29.217 -0.054  43.056  1   25.51  ? 43  GLY C O   1 
ATOM   4837 N  N   . VAL C 1 48  ? -29.581 -1.61   41.464  1   21.28  ? 44  VAL C N   1 
ATOM   4838 C  CA  . VAL C 1 48  ? -30.078 -0.657  40.496  1   20.07  ? 44  VAL C CA  1 
ATOM   4839 C  C   . VAL C 1 48  ? -31.459 -0.22   40.963  1   21.03  ? 44  VAL C C   1 
ATOM   4840 O  O   . VAL C 1 48  ? -32.322 -1.058  41.204  1   21.07  ? 44  VAL C O   1 
ATOM   4841 C  CB  . VAL C 1 48  ? -30.145 -1.244  39.069  1   19.25  ? 44  VAL C CB  1 
ATOM   4842 C  CG1 . VAL C 1 48  ? -30.515 -0.18   38.068  1   17.65  ? 44  VAL C CG1 1 
ATOM   4843 C  CG2 . VAL C 1 48  ? -28.849 -1.933  38.688  1   20.1   ? 44  VAL C CG2 1 
ATOM   4844 N  N   . PRO C 1 49  ? -31.728 1.098   41.092  1   22.32  ? 45  PRO C N   1 
ATOM   4845 C  CA  . PRO C 1 49  ? -33.035 1.548   41.571  1   21.35  ? 45  PRO C CA  1 
ATOM   4846 C  C   . PRO C 1 49  ? -34.145 1.272   40.56   1   22.98  ? 45  PRO C C   1 
ATOM   4847 O  O   . PRO C 1 49  ? -33.934 1.342   39.343  1   22.62  ? 45  PRO C O   1 
ATOM   4848 C  CB  . PRO C 1 49  ? -32.829 3.044   41.833  1   21.01  ? 45  PRO C CB  1 
ATOM   4849 C  CG  . PRO C 1 49  ? -31.644 3.439   41.013  1   21.11  ? 45  PRO C CG  1 
ATOM   4850 C  CD  . PRO C 1 49  ? -30.796 2.203   40.803  1   20.8   ? 45  PRO C CD  1 
ATOM   4851 N  N   . SER C 1 50  ? -35.335 0.964   41.09   1   22.98  ? 46  SER C N   1 
ATOM   4852 C  CA  . SER C 1 50  ? -36.472 0.635   40.253  1   26.76  ? 46  SER C CA  1 
ATOM   4853 C  C   . SER C 1 50  ? -36.911 1.783   39.35   1   26.25  ? 46  SER C C   1 
ATOM   4854 O  O   . SER C 1 50  ? -37.446 1.546   38.264  1   29.71  ? 46  SER C O   1 
ATOM   4855 C  CB  . SER C 1 50  ? -37.632 0.147   41.113  1   29.44  ? 46  SER C CB  1 
ATOM   4856 O  OG  . SER C 1 50  ? -38.007 1.109   42.077  1   30.56  ? 46  SER C OG  1 
ATOM   4857 N  N   . THR C 1 51  ? -36.708 3.023   39.811  1   27.28  ? 47  THR C N   1 
ATOM   4858 C  CA  . THR C 1 51  ? -36.944 4.204   38.992  1   27.97  ? 47  THR C CA  1 
ATOM   4859 C  C   . THR C 1 51  ? -36.181 4.094   37.675  1   25.48  ? 47  THR C C   1 
ATOM   4860 O  O   . THR C 1 51  ? -36.728 4.358   36.616  1   26.81  ? 47  THR C O   1 
ATOM   4861 C  CB  . THR C 1 51  ? -36.534 5.473   39.742  1   30.51  ? 47  THR C CB  1 
ATOM   4862 O  OG1 . THR C 1 51  ? -37.303 5.57    40.928  1   37.45  ? 47  THR C OG1 1 
ATOM   4863 C  CG2 . THR C 1 51  ? -36.762 6.698   38.96   1   34.86  ? 47  THR C CG2 1 
ATOM   4864 N  N   . ALA C 1 52  ? -34.913 3.686   37.753  1   22.73  ? 48  ALA C N   1 
ATOM   4865 C  CA  . ALA C 1 52  ? -34.069 3.616   36.577  1   22.11  ? 48  ALA C CA  1 
ATOM   4866 C  C   . ALA C 1 52  ? -34.408 2.4     35.716  1   21.54  ? 48  ALA C C   1 
ATOM   4867 O  O   . ALA C 1 52  ? -34.353 2.481   34.497  1   21.77  ? 48  ALA C O   1 
ATOM   4868 C  CB  . ALA C 1 52  ? -32.598 3.606   36.991  1   22.46  ? 48  ALA C CB  1 
ATOM   4869 N  N   . ILE C 1 53  ? -34.755 1.273   36.345  1   23.02  ? 49  ILE C N   1 
ATOM   4870 C  CA  . ILE C 1 53  ? -35.186 0.087   35.621  1   24.79  ? 49  ILE C CA  1 
ATOM   4871 C  C   . ILE C 1 53  ? -36.44  0.353   34.791  1   27.01  ? 49  ILE C C   1 
ATOM   4872 O  O   . ILE C 1 53  ? -36.537 -0.073  33.642  1   26.6   ? 49  ILE C O   1 
ATOM   4873 C  CB  . ILE C 1 53  ? -35.397 -1.081  36.598  1   25     ? 49  ILE C CB  1 
ATOM   4874 C  CG1 . ILE C 1 53  ? -34.054 -1.594  37.104  1   23.9   ? 49  ILE C CG1 1 
ATOM   4875 C  CG2 . ILE C 1 53  ? -36.221 -2.201  35.963  1   25.43  ? 49  ILE C CG2 1 
ATOM   4876 C  CD1 . ILE C 1 53  ? -34.159 -2.332  38.359  1   25.76  ? 49  ILE C CD1 1 
ATOM   4877 N  N   . ARG C 1 54  ? -37.396 1.075   35.374  1   29     ? 50  ARG C N   1 
ATOM   4878 C  CA  . ARG C 1 54  ? -38.564 1.5     34.619  1   31.44  ? 50  ARG C CA  1 
ATOM   4879 C  C   . ARG C 1 54  ? -38.251 2.552   33.559  1   31.4   ? 50  ARG C C   1 
ATOM   4880 O  O   . ARG C 1 54  ? -38.694 2.416   32.423  1   33.65  ? 50  ARG C O   1 
ATOM   4881 C  CB  . ARG C 1 54  ? -39.643 2.016   35.56   1   29.79  ? 50  ARG C CB  1 
ATOM   4882 C  CG  . ARG C 1 54  ? -40.31  0.883   36.332  1   28.85  ? 50  ARG C CG  1 
ATOM   4883 C  CD  . ARG C 1 54  ? -41.41  1.425   37.178  1   27.41  ? 50  ARG C CD  1 
ATOM   4884 N  NE  . ARG C 1 54  ? -41.989 0.423   38.054  1   26.28  ? 50  ARG C NE  1 
ATOM   4885 C  CZ  . ARG C 1 54  ? -42.805 0.716   39.053  1   27.12  ? 50  ARG C CZ  1 
ATOM   4886 N  NH1 . ARG C 1 54  ? -43.091 1.976   39.364  1   23.8   ? 50  ARG C NH1 1 
ATOM   4887 N  NH2 . ARG C 1 54  ? -43.352 -0.274  39.755  1   27.63  ? 50  ARG C NH2 1 
ATOM   4888 N  N   . GLU C 1 55  ? -37.493 3.594   33.924  1   30.78  ? 51  GLU C N   1 
ATOM   4889 C  CA  . GLU C 1 55  ? -37.175 4.638   32.963  1   33.17  ? 51  GLU C CA  1 
ATOM   4890 C  C   . GLU C 1 55  ? -36.502 4.053   31.722  1   28.92  ? 51  GLU C C   1 
ATOM   4891 O  O   . GLU C 1 55  ? -36.935 4.296   30.608  1   27.8   ? 51  GLU C O   1 
ATOM   4892 C  CB  . GLU C 1 55  ? -36.298 5.762   33.559  1   36.81  ? 51  GLU C CB  1 
ATOM   4893 C  CG  . GLU C 1 55  ? -35.862 6.779   32.5    1   40.5   ? 51  GLU C CG  1 
ATOM   4894 C  CD  . GLU C 1 55  ? -35.641 8.199   32.969  1   38.24  ? 51  GLU C CD  1 
ATOM   4895 O  OE1 . GLU C 1 55  ? -35.125 8.372   34.087  1   33.9   ? 51  GLU C OE1 1 
ATOM   4896 O  OE2 . GLU C 1 55  ? -35.997 9.145   32.223  1   46.94  ? 51  GLU C OE2 1 
ATOM   4897 N  N   . ILE C 1 56  ? -35.447 3.267   31.922  1   29.87  ? 52  ILE C N   1 
ATOM   4898 C  CA  . ILE C 1 56  ? -34.657 2.765   30.808  1   28.48  ? 52  ILE C CA  1 
ATOM   4899 C  C   . ILE C 1 56  ? -35.469 1.773   29.976  1   28.26  ? 52  ILE C C   1 
ATOM   4900 O  O   . ILE C 1 56  ? -35.556 1.922   28.759  1   25.53  ? 52  ILE C O   1 
ATOM   4901 C  CB  . ILE C 1 56  ? -33.336 2.133   31.307  1   26.28  ? 52  ILE C CB  1 
ATOM   4902 C  CG1 . ILE C 1 56  ? -32.459 3.166   32.052  1   25.53  ? 52  ILE C CG1 1 
ATOM   4903 C  CG2 . ILE C 1 56  ? -32.584 1.494   30.153  1   26.79  ? 52  ILE C CG2 1 
ATOM   4904 C  CD1 . ILE C 1 56  ? -31.399 2.569   32.968  1   26.16  ? 52  ILE C CD1 1 
ATOM   4905 N  N   . SER C 1 57  ? -36.058 0.769   30.64   1   28.36  ? 53  SER C N   1 
ATOM   4906 C  CA  . SER C 1 57  ? -36.835 -0.252  29.948  1   31.25  ? 53  SER C CA  1 
ATOM   4907 C  C   . SER C 1 57  ? -37.997 0.33    29.142  1   30.72  ? 53  SER C C   1 
ATOM   4908 O  O   . SER C 1 57  ? -38.239 -0.097  28.019  1   28.71  ? 53  SER C O   1 
ATOM   4909 C  CB  . SER C 1 57  ? -37.361 -1.311  30.921  1   32.28  ? 53  SER C CB  1 
ATOM   4910 O  OG  . SER C 1 57  ? -38.311 -0.785  31.833  1   34.56  ? 53  SER C OG  1 
ATOM   4911 N  N   . LEU C 1 58  ? -38.704 1.315   29.704  1   31.19  ? 54  LEU C N   1 
ATOM   4912 C  CA  . LEU C 1 58  ? -39.838 1.901   29.002  1   33.46  ? 54  LEU C CA  1 
ATOM   4913 C  C   . LEU C 1 58  ? -39.408 2.837   27.874  1   32.42  ? 54  LEU C C   1 
ATOM   4914 O  O   . LEU C 1 58  ? -40     2.787   26.8    1   34.91  ? 54  LEU C O   1 
ATOM   4915 C  CB  . LEU C 1 58  ? -40.777 2.605   29.988  1   31.77  ? 54  LEU C CB  1 
ATOM   4916 C  CG  . LEU C 1 58  ? -41.34  1.649   31.039  1   31.89  ? 54  LEU C CG  1 
ATOM   4917 C  CD1 . LEU C 1 58  ? -42.253 2.347   32.003  1   32.52  ? 54  LEU C CD1 1 
ATOM   4918 C  CD2 . LEU C 1 58  ? -42.039 0.518   30.406  1   31.49  ? 54  LEU C CD2 1 
ATOM   4919 N  N   . LEU C 1 59  ? -38.362 3.645   28.087  1   31.4   ? 55  LEU C N   1 
ATOM   4920 C  CA  . LEU C 1 59  ? -37.862 4.527   27.037  1   33.43  ? 55  LEU C CA  1 
ATOM   4921 C  C   . LEU C 1 59  ? -37.242 3.79    25.846  1   34.71  ? 55  LEU C C   1 
ATOM   4922 O  O   . LEU C 1 59  ? -37.212 4.312   24.741  1   38.92  ? 55  LEU C O   1 
ATOM   4923 C  CB  . LEU C 1 59  ? -36.818 5.507   27.591  1   34.23  ? 55  LEU C CB  1 
ATOM   4924 C  CG  . LEU C 1 59  ? -37.349 6.746   28.259  1   36.45  ? 55  LEU C CG  1 
ATOM   4925 C  CD1 . LEU C 1 59  ? -36.217 7.629   28.667  1   37.55  ? 55  LEU C CD1 1 
ATOM   4926 C  CD2 . LEU C 1 59  ? -38.305 7.496   27.354  1   38.55  ? 55  LEU C CD2 1 
ATOM   4927 N  N   . LYS C 1 60  ? -36.724 2.582   26.071  1   39.38  ? 56  LYS C N   1 
ATOM   4928 C  CA  . LYS C 1 60  ? -36.191 1.771   24.988  1   44.07  ? 56  LYS C CA  1 
ATOM   4929 C  C   . LYS C 1 60  ? -37.283 1.387   23.99   1   43.59  ? 56  LYS C C   1 
ATOM   4930 O  O   . LYS C 1 60  ? -37.025 1.306   22.796  1   42.98  ? 56  LYS C O   1 
ATOM   4931 C  CB  . LYS C 1 60  ? -35.493 0.516   25.531  1   47.04  ? 56  LYS C CB  1 
ATOM   4932 C  CG  . LYS C 1 60  ? -34.072 0.781   25.99   1   47.6   ? 56  LYS C CG  1 
ATOM   4933 C  CD  . LYS C 1 60  ? -33.393 -0.478  26.472  1   54.93  ? 56  LYS C CD  1 
ATOM   4934 C  CE  . LYS C 1 60  ? -33.051 -1.42   25.332  1   60.75  ? 56  LYS C CE  1 
ATOM   4935 N  NZ  . LYS C 1 60  ? -31.829 -0.982  24.616  1   64.63  ? 56  LYS C NZ  1 
ATOM   4936 N  N   . GLU C 1 61  ? -38.503 1.175   24.486  1   45.01  ? 57  GLU C N   1 
ATOM   4937 C  CA  . GLU C 1 61  ? -39.645 0.885   23.64   1   44.7   ? 57  GLU C CA  1 
ATOM   4938 C  C   . GLU C 1 61  ? -40.224 2.113   22.937  1   43.43  ? 57  GLU C C   1 
ATOM   4939 O  O   . GLU C 1 61  ? -40.67  2.03    21.795  1   50.4   ? 57  GLU C O   1 
ATOM   4940 C  CB  . GLU C 1 61  ? -40.743 0.226   24.485  1   47.27  ? 57  GLU C CB  1 
ATOM   4941 C  CG  . GLU C 1 61  ? -40.372 -1.165  24.952  1   44.8   ? 57  GLU C CG  1 
ATOM   4942 C  CD  . GLU C 1 61  ? -41.526 -2.018  25.44   1   44.08  ? 57  GLU C CD  1 
ATOM   4943 O  OE1 . GLU C 1 61  ? -42.705 -1.636  25.245  1   43.24  ? 57  GLU C OE1 1 
ATOM   4944 O  OE2 . GLU C 1 61  ? -41.247 -3.091  26.017  1   48.28  ? 57  GLU C OE2 1 
ATOM   4945 N  N   . LEU C 1 62  ? -40.223 3.252   23.627  1   42.06  ? 58  LEU C N   1 
ATOM   4946 C  CA  . LEU C 1 62  ? -40.962 4.414   23.169  1   40.96  ? 58  LEU C CA  1 
ATOM   4947 C  C   . LEU C 1 62  ? -40.113 5.255   22.22   1   38.94  ? 58  LEU C C   1 
ATOM   4948 O  O   . LEU C 1 62  ? -39.393 6.154   22.65   1   42.41  ? 58  LEU C O   1 
ATOM   4949 C  CB  . LEU C 1 62  ? -41.397 5.237   24.389  1   42.51  ? 58  LEU C CB  1 
ATOM   4950 C  CG  . LEU C 1 62  ? -42.353 4.539   25.373  1   41.66  ? 58  LEU C CG  1 
ATOM   4951 C  CD1 . LEU C 1 62  ? -42.635 5.409   26.562  1   42.76  ? 58  LEU C CD1 1 
ATOM   4952 C  CD2 . LEU C 1 62  ? -43.656 4.161   24.717  1   43.33  ? 58  LEU C CD2 1 
ATOM   4953 N  N   . ASN C 1 63  ? -40.231 4.983   20.919  1   35.7   ? 59  ASN C N   1 
ATOM   4954 C  CA  . ASN C 1 63  ? -39.558 5.794   19.917  1   37.25  ? 59  ASN C CA  1 
ATOM   4955 C  C   . ASN C 1 63  ? -40.558 6.65    19.145  1   29.88  ? 59  ASN C C   1 
ATOM   4956 O  O   . ASN C 1 63  ? -41.306 6.149   18.322  1   29.86  ? 59  ASN C O   1 
ATOM   4957 C  CB  . ASN C 1 63  ? -38.72  4.911   19.01   1   46.47  ? 59  ASN C CB  1 
ATOM   4958 C  CG  . ASN C 1 63  ? -37.58  4.29    19.813  1   61.14  ? 59  ASN C CG  1 
ATOM   4959 O  OD1 . ASN C 1 63  ? -36.651 4.985   20.262  1   70.5   ? 59  ASN C OD1 1 
ATOM   4960 N  ND2 . ASN C 1 63  ? -37.639 2.986   20.06   1   63.77  ? 59  ASN C ND2 1 
ATOM   4961 N  N   . HIS C 1 64  ? -40.571 7.954   19.448  1   33.52  ? 60  HIS C N   1 
ATOM   4962 C  CA  . HIS C 1 64  ? -41.53  8.889   18.875  1   32.53  ? 60  HIS C CA  1 
ATOM   4963 C  C   . HIS C 1 64  ? -40.937 10.296  18.877  1   30.82  ? 60  HIS C C   1 
ATOM   4964 O  O   . HIS C 1 64  ? -40.182 10.655  19.776  1   31.51  ? 60  HIS C O   1 
ATOM   4965 C  CB  . HIS C 1 64  ? -42.856 8.837   19.653  1   30.02  ? 60  HIS C CB  1 
ATOM   4966 C  CG  . HIS C 1 64  ? -43.949 9.67    19.053  1   32.33  ? 60  HIS C CG  1 
ATOM   4967 N  ND1 . HIS C 1 64  ? -44.061 11.021  19.329  1   33.87  ? 60  HIS C ND1 1 
ATOM   4968 C  CD2 . HIS C 1 64  ? -44.963 9.315   18.231  1   32.26  ? 60  HIS C CD2 1 
ATOM   4969 C  CE1 . HIS C 1 64  ? -45.123 11.451  18.646  1   33.41  ? 60  HIS C CE1 1 
ATOM   4970 N  NE2 . HIS C 1 64  ? -45.69  10.463  17.965  1   30.69  ? 60  HIS C NE2 1 
ATOM   4971 N  N   . PRO C 1 65  ? -41.236 11.148  17.874  1   31.77  ? 61  PRO C N   1 
ATOM   4972 C  CA  . PRO C 1 65  ? -40.64  12.487  17.822  1   32.17  ? 61  PRO C CA  1 
ATOM   4973 C  C   . PRO C 1 65  ? -40.941 13.388  19.017  1   31.59  ? 61  PRO C C   1 
ATOM   4974 O  O   . PRO C 1 65  ? -40.186 14.326  19.26   1   30.41  ? 61  PRO C O   1 
ATOM   4975 C  CB  . PRO C 1 65  ? -41.212 13.089  16.535  1   32.28  ? 61  PRO C CB  1 
ATOM   4976 C  CG  . PRO C 1 65  ? -41.694 11.91   15.733  1   32.94  ? 61  PRO C CG  1 
ATOM   4977 C  CD  . PRO C 1 65  ? -42.11  10.863  16.725  1   31.91  ? 61  PRO C CD  1 
ATOM   4978 N  N   . ASN C 1 66  ? -42.026 13.096  19.755  1   28.93  ? 62  ASN C N   1 
ATOM   4979 C  CA  . ASN C 1 66  ? -42.406 13.888  20.913  1   30.17  ? 62  ASN C CA  1 
ATOM   4980 C  C   . ASN C 1 66  ? -42.172 13.161  22.243  1   30.89  ? 62  ASN C C   1 
ATOM   4981 O  O   . ASN C 1 66  ? -42.773 13.487  23.268  1   28.86  ? 62  ASN C O   1 
ATOM   4982 C  CB  . ASN C 1 66  ? -43.849 14.321  20.752  1   29.77  ? 62  ASN C CB  1 
ATOM   4983 C  CG  . ASN C 1 66  ? -44.058 15.126  19.5    1   30.8   ? 62  ASN C CG  1 
ATOM   4984 O  OD1 . ASN C 1 66  ? -44.752 14.705  18.599  1   34.4   ? 62  ASN C OD1 1 
ATOM   4985 N  ND2 . ASN C 1 66  ? -43.465 16.3    19.397  1   32.51  ? 62  ASN C ND2 1 
ATOM   4986 N  N   . ILE C 1 67  ? -41.284 12.162  22.213  1   29.79  ? 63  ILE C N   1 
ATOM   4987 C  CA  . ILE C 1 67  ? -40.774 11.538  23.415  1   29.04  ? 63  ILE C CA  1 
ATOM   4988 C  C   . ILE C 1 67  ? -39.253 11.663  23.381  1   30.48  ? 63  ILE C C   1 
ATOM   4989 O  O   . ILE C 1 67  ? -38.626 11.315  22.373  1   27.05  ? 63  ILE C O   1 
ATOM   4990 C  CB  . ILE C 1 67  ? -41.253 10.078  23.529  1   26.29  ? 63  ILE C CB  1 
ATOM   4991 C  CG1 . ILE C 1 67  ? -42.789 9.992   23.572  1   27.46  ? 63  ILE C CG1 1 
ATOM   4992 C  CG2 . ILE C 1 67  ? -40.613 9.409   24.733  1   27.89  ? 63  ILE C CG2 1 
ATOM   4993 C  CD1 . ILE C 1 67  ? -43.361 8.515   23.523  1   29.07  ? 63  ILE C CD1 1 
ATOM   4994 N  N   . VAL C 1 68  ? -38.68  12.157  24.494  1   29.24  ? 64  VAL C N   1 
ATOM   4995 C  CA  . VAL C 1 68  ? -37.242 12.33   24.604  1   28.52  ? 64  VAL C CA  1 
ATOM   4996 C  C   . VAL C 1 68  ? -36.557 11.007  24.259  1   30.01  ? 64  VAL C C   1 
ATOM   4997 O  O   . VAL C 1 68  ? -36.984 9.933   24.693  1   27     ? 64  VAL C O   1 
ATOM   4998 C  CB  . VAL C 1 68  ? -36.813 12.839  25.993  1   27.26  ? 64  VAL C CB  1 
ATOM   4999 C  CG1 . VAL C 1 68  ? -37.085 11.799  27.086  1   26.57  ? 64  VAL C CG1 1 
ATOM   5000 C  CG2 . VAL C 1 68  ? -35.344 13.25   26.011  1   29.43  ? 64  VAL C CG2 1 
ATOM   5001 N  N   . LYS C 1 69  ? -35.491 11.116  23.466  1   28.46  ? 65  LYS C N   1 
ATOM   5002 C  CA  . LYS C 1 69  ? -34.777 9.957   22.975  1   31.41  ? 65  LYS C CA  1 
ATOM   5003 C  C   . LYS C 1 69  ? -33.629 9.584   23.911  1   28.52  ? 65  LYS C C   1 
ATOM   5004 O  O   . LYS C 1 69  ? -32.743 10.395  24.186  1   26.11  ? 65  LYS C O   1 
ATOM   5005 C  CB  . LYS C 1 69  ? -34.272 10.25   21.557  1   34.6   ? 65  LYS C CB  1 
ATOM   5006 C  CG  . LYS C 1 69  ? -33.628 9.055   20.912  1   43.34  ? 65  LYS C CG  1 
ATOM   5007 C  CD  . LYS C 1 69  ? -33.581 9.115   19.37   1   52.52  ? 65  LYS C CD  1 
ATOM   5008 C  CE  . LYS C 1 69  ? -32.848 7.912   18.766  1   54.32  ? 65  LYS C CE  1 
ATOM   5009 N  NZ  . LYS C 1 69  ? -33.317 6.617   19.345  1   54.1   ? 65  LYS C NZ  1 
ATOM   5010 N  N   . LEU C 1 70  ? -33.666 8.338   24.398  1   28.94  ? 66  LEU C N   1 
ATOM   5011 C  CA  . LEU C 1 70  ? -32.542 7.721   25.088  1   29.1   ? 66  LEU C CA  1 
ATOM   5012 C  C   . LEU C 1 70  ? -31.588 7.164   24.031  1   27.44  ? 66  LEU C C   1 
ATOM   5013 O  O   . LEU C 1 70  ? -31.976 6.304   23.257  1   28.05  ? 66  LEU C O   1 
ATOM   5014 C  CB  . LEU C 1 70  ? -33.054 6.6     26.006  1   27.37  ? 66  LEU C CB  1 
ATOM   5015 C  CG  . LEU C 1 70  ? -32.01  5.882   26.856  1   29.56  ? 66  LEU C CG  1 
ATOM   5016 C  CD1 . LEU C 1 70  ? -31.245 6.841   27.748  1   28.35  ? 66  LEU C CD1 1 
ATOM   5017 C  CD2 . LEU C 1 70  ? -32.67  4.836   27.721  1   30.86  ? 66  LEU C CD2 1 
ATOM   5018 N  N   . LEU C 1 71  ? -30.359 7.682   23.973  1   27.54  ? 67  LEU C N   1 
ATOM   5019 C  CA  . LEU C 1 71  ? -29.412 7.299   22.933  1   26.97  ? 67  LEU C CA  1 
ATOM   5020 C  C   . LEU C 1 71  ? -28.57  6.085   23.322  1   26.13  ? 67  LEU C C   1 
ATOM   5021 O  O   . LEU C 1 71  ? -28.222 5.264   22.474  1   24.6   ? 67  LEU C O   1 
ATOM   5022 C  CB  . LEU C 1 71  ? -28.475 8.482   22.622  1   27.5   ? 67  LEU C CB  1 
ATOM   5023 C  CG  . LEU C 1 71  ? -29.164 9.766   22.191  1   29.96  ? 67  LEU C CG  1 
ATOM   5024 C  CD1 . LEU C 1 71  ? -28.154 10.926  22.088  1   30.05  ? 67  LEU C CD1 1 
ATOM   5025 C  CD2 . LEU C 1 71  ? -29.872 9.566   20.858  1   30.53  ? 67  LEU C CD2 1 
ATOM   5026 N  N   . ASP C 1 72  ? -28.241 5.977   24.612  1   25.27  ? 68  ASP C N   1 
ATOM   5027 C  CA  . ASP C 1 72  ? -27.339 4.936   25.065  1   25.38  ? 68  ASP C CA  1 
ATOM   5028 C  C   . ASP C 1 72  ? -27.41  4.788   26.58   1   26.72  ? 68  ASP C C   1 
ATOM   5029 O  O   . ASP C 1 72  ? -27.908 5.67    27.289  1   26.69  ? 68  ASP C O   1 
ATOM   5030 C  CB  . ASP C 1 72  ? -25.903 5.275   24.636  1   25.91  ? 68  ASP C CB  1 
ATOM   5031 C  CG  . ASP C 1 72  ? -24.959 4.101   24.483  1   25.95  ? 68  ASP C CG  1 
ATOM   5032 O  OD1 . ASP C 1 72  ? -25.368 2.974   24.764  1   27.27  ? 68  ASP C OD1 1 
ATOM   5033 O  OD2 . ASP C 1 72  ? -23.8   4.317   24.064  1   27.89  ? 68  ASP C OD2 1 
ATOM   5034 N  N   . VAL C 1 73  ? -26.901 3.651   27.053  1   26.58  ? 69  VAL C N   1 
ATOM   5035 C  CA  . VAL C 1 73  ? -26.782 3.392   28.476  1   29.69  ? 69  VAL C CA  1 
ATOM   5036 C  C   . VAL C 1 73  ? -25.39  2.84    28.73   1   28.59  ? 69  VAL C C   1 
ATOM   5037 O  O   . VAL C 1 73  ? -25.078 1.746   28.269  1   28.78  ? 69  VAL C O   1 
ATOM   5038 C  CB  . VAL C 1 73  ? -27.86  2.421   28.984  1   27.97  ? 69  VAL C CB  1 
ATOM   5039 C  CG1 . VAL C 1 73  ? -27.667 2.177   30.479  1   28.31  ? 69  VAL C CG1 1 
ATOM   5040 C  CG2 . VAL C 1 73  ? -29.259 2.942   28.673  1   27.7   ? 69  VAL C CG2 1 
ATOM   5041 N  N   . ILE C 1 74  ? -24.568 3.612   29.447  1   29.9   ? 70  ILE C N   1 
ATOM   5042 C  CA  . ILE C 1 74  ? -23.18  3.241   29.659  1   33.56  ? 70  ILE C CA  1 
ATOM   5043 C  C   . ILE C 1 74  ? -23.017 2.706   31.077  1   32.88  ? 70  ILE C C   1 
ATOM   5044 O  O   . ILE C 1 74  ? -23.329 3.379   32.056  1   30.07  ? 70  ILE C O   1 
ATOM   5045 C  CB  . ILE C 1 74  ? -22.255 4.425   29.298  1   34.45  ? 70  ILE C CB  1 
ATOM   5046 C  CG1 . ILE C 1 74  ? -22.452 4.786   27.8    1   34.34  ? 70  ILE C CG1 1 
ATOM   5047 C  CG2 . ILE C 1 74  ? -20.783 4.124   29.616  1   32.46  ? 70  ILE C CG2 1 
ATOM   5048 C  CD1 . ILE C 1 74  ? -21.792 6.021   27.375  1   36.51  ? 70  ILE C CD1 1 
ATOM   5049 N  N   . HIS C 1 75  ? -22.555 1.457   31.143  1   39.95  ? 71  HIS C N   1 
ATOM   5050 C  CA  . HIS C 1 75  ? -22.409 0.74    32.393  1   43.7   ? 71  HIS C CA  1 
ATOM   5051 C  C   . HIS C 1 75  ? -20.973 0.848   32.893  1   42.63  ? 71  HIS C C   1 
ATOM   5052 O  O   . HIS C 1 75  ? -20.026 0.795   32.118  1   40.37  ? 71  HIS C O   1 
ATOM   5053 C  CB  . HIS C 1 75  ? -22.751 -0.744  32.232  1   45.7   ? 71  HIS C CB  1 
ATOM   5054 C  CG  . HIS C 1 75  ? -24.153 -1.076  31.811  1   45.84  ? 71  HIS C CG  1 
ATOM   5055 N  ND1 . HIS C 1 75  ? -25.077 -1.563  32.716  1   42.52  ? 71  HIS C ND1 1 
ATOM   5056 C  CD2 . HIS C 1 75  ? -24.731 -1.013  30.589  1   45.69  ? 71  HIS C CD2 1 
ATOM   5057 C  CE1 . HIS C 1 75  ? -26.183 -1.777  32.028  1   44.94  ? 71  HIS C CE1 1 
ATOM   5058 N  NE2 . HIS C 1 75  ? -26.019 -1.462  30.735  1   44.31  ? 71  HIS C NE2 1 
ATOM   5059 N  N   . THR C 1 76  ? -20.831 1.069   34.194  1   44.18  ? 72  THR C N   1 
ATOM   5060 C  CA  . THR C 1 76  ? -19.627 0.692   34.918  1   39.8   ? 72  THR C CA  1 
ATOM   5061 C  C   . THR C 1 76  ? -20.13  -0.238  36.016  1   36.94  ? 72  THR C C   1 
ATOM   5062 O  O   . THR C 1 76  ? -21.331 -0.488  36.13   1   29.92  ? 72  THR C O   1 
ATOM   5063 C  CB  . THR C 1 76  ? -18.807 1.921   35.427  1   38.32  ? 72  THR C CB  1 
ATOM   5064 O  OG1 . THR C 1 76  ? -19.577 2.699   36.338  1   38.73  ? 72  THR C OG1 1 
ATOM   5065 C  CG2 . THR C 1 76  ? -18.35  2.823   34.296  1   40.9   ? 72  THR C CG2 1 
ATOM   5066 N  N   . GLU C 1 77  ? -19.195 -0.75   36.816  1   40.63  ? 73  GLU C N   1 
ATOM   5067 C  CA  . GLU C 1 77  ? -19.544 -1.535  37.987  1   44.87  ? 73  GLU C CA  1 
ATOM   5068 C  C   . GLU C 1 77  ? -20.294 -0.679  39.01   1   39.69  ? 73  GLU C C   1 
ATOM   5069 O  O   . GLU C 1 77  ? -21.167 -1.182  39.713  1   39.72  ? 73  GLU C O   1 
ATOM   5070 C  CB  . GLU C 1 77  ? -18.273 -2.134  38.601  1   51.44  ? 73  GLU C CB  1 
ATOM   5071 C  CG  . GLU C 1 77  ? -18.544 -3.188  39.66   1   59.85  ? 73  GLU C CG  1 
ATOM   5072 C  CD  . GLU C 1 77  ? -17.389 -3.444  40.607  1   65.39  ? 73  GLU C CD  1 
ATOM   5073 O  OE1 . GLU C 1 77  ? -16.221 -3.19   40.234  1   64.86  ? 73  GLU C OE1 1 
ATOM   5074 O  OE2 . GLU C 1 77  ? -17.664 -3.885  41.747  1   75.3   ? 73  GLU C OE2 1 
ATOM   5075 N  N   . ASN C 1 78  ? -19.962 0.619   39.07   1   35.01  ? 74  ASN C N   1 
ATOM   5076 C  CA  . ASN C 1 78  ? -20.469 1.511   40.105  1   34.76  ? 74  ASN C CA  1 
ATOM   5077 C  C   . ASN C 1 78  ? -21.472 2.565   39.644  1   33.16  ? 74  ASN C C   1 
ATOM   5078 O  O   . ASN C 1 78  ? -22.16  3.166   40.468  1   30.93  ? 74  ASN C O   1 
ATOM   5079 C  CB  . ASN C 1 78  ? -19.289 2.196   40.803  1   34.07  ? 74  ASN C CB  1 
ATOM   5080 C  CG  . ASN C 1 78  ? -18.515 1.235   41.69   1   35.47  ? 74  ASN C CG  1 
ATOM   5081 O  OD1 . ASN C 1 78  ? -17.339 0.946   41.45   1   36.79  ? 74  ASN C OD1 1 
ATOM   5082 N  ND2 . ASN C 1 78  ? -19.161 0.691   42.738  1   36.81  ? 74  ASN C ND2 1 
ATOM   5083 N  N   . LYS C 1 79  ? -21.577 2.78    38.327  1   38.07  ? 75  LYS C N   1 
ATOM   5084 C  CA  . LYS C 1 79  ? -22.48  3.791   37.8    1   36.6   ? 75  LYS C CA  1 
ATOM   5085 C  C   . LYS C 1 79  ? -23.209 3.366   36.537  1   33.2   ? 75  LYS C C   1 
ATOM   5086 O  O   . LYS C 1 79  ? -22.752 2.513   35.784  1   38.68  ? 75  LYS C O   1 
ATOM   5087 C  CB  . LYS C 1 79  ? -21.725 5.091   37.492  1   42.85  ? 75  LYS C CB  1 
ATOM   5088 C  CG  . LYS C 1 79  ? -21.308 5.874   38.717  1   50.99  ? 75  LYS C CG  1 
ATOM   5089 C  CD  . LYS C 1 79  ? -20.042 6.698   38.482  1   58.71  ? 75  LYS C CD  1 
ATOM   5090 C  CE  . LYS C 1 79  ? -19.443 7.148   39.788  1   65.2   ? 75  LYS C CE  1 
ATOM   5091 N  NZ  . LYS C 1 79  ? -18.071 7.687   39.616  1   66.39  ? 75  LYS C NZ  1 
ATOM   5092 N  N   . LEU C 1 80  ? -24.357 4.016   36.342  1   32.34  ? 76  LEU C N   1 
ATOM   5093 C  CA  . LEU C 1 80  ? -25.093 4.041   35.097  1   32.58  ? 76  LEU C CA  1 
ATOM   5094 C  C   . LEU C 1 80  ? -25.097 5.476   34.583  1   32.44  ? 76  LEU C C   1 
ATOM   5095 O  O   . LEU C 1 80  ? -25.417 6.402   35.333  1   32.79  ? 76  LEU C O   1 
ATOM   5096 C  CB  . LEU C 1 80  ? -26.55  3.599   35.327  1   35.31  ? 76  LEU C CB  1 
ATOM   5097 C  CG  . LEU C 1 80  ? -26.829 2.136   35.241  1   39.35  ? 76  LEU C CG  1 
ATOM   5098 C  CD1 . LEU C 1 80  ? -28.316 1.873   35.366  1   38.66  ? 76  LEU C CD1 1 
ATOM   5099 C  CD2 . LEU C 1 80  ? -26.261 1.545   33.946  1   43.96  ? 76  LEU C CD2 1 
ATOM   5100 N  N   . TYR C 1 81  ? -24.74  5.646   33.307  1   29.87  ? 77  TYR C N   1 
ATOM   5101 C  CA  . TYR C 1 81  ? -24.915 6.916   32.623  1   31.31  ? 77  TYR C CA  1 
ATOM   5102 C  C   . TYR C 1 81  ? -25.965 6.752   31.532  1   31.65  ? 77  TYR C C   1 
ATOM   5103 O  O   . TYR C 1 81  ? -25.809 5.912   30.651  1   33.25  ? 77  TYR C O   1 
ATOM   5104 C  CB  . TYR C 1 81  ? -23.623 7.396   31.986  1   33.34  ? 77  TYR C CB  1 
ATOM   5105 C  CG  . TYR C 1 81  ? -22.549 7.844   32.946  1   33.97  ? 77  TYR C CG  1 
ATOM   5106 C  CD1 . TYR C 1 81  ? -22.554 9.124   33.471  1   38.06  ? 77  TYR C CD1 1 
ATOM   5107 C  CD2 . TYR C 1 81  ? -21.517 6.994   33.308  1   36.49  ? 77  TYR C CD2 1 
ATOM   5108 C  CE1 . TYR C 1 81  ? -21.56  9.553   34.34   1   40.83  ? 77  TYR C CE1 1 
ATOM   5109 C  CE2 . TYR C 1 81  ? -20.515 7.406   34.178  1   40.7   ? 77  TYR C CE2 1 
ATOM   5110 C  CZ  . TYR C 1 81  ? -20.536 8.69    34.69   1   42.74  ? 77  TYR C CZ  1 
ATOM   5111 O  OH  . TYR C 1 81  ? -19.541 9.096   35.552  1   54.83  ? 77  TYR C OH  1 
ATOM   5112 N  N   . LEU C 1 82  ? -27.029 7.557   31.605  1   29.45  ? 78  LEU C N   1 
ATOM   5113 C  CA  . LEU C 1 82  ? -28.028 7.589   30.558  1   33.84  ? 78  LEU C CA  1 
ATOM   5114 C  C   . LEU C 1 82  ? -27.694 8.741   29.61   1   31.88  ? 78  LEU C C   1 
ATOM   5115 O  O   . LEU C 1 82  ? -27.575 9.878   30.053  1   30.02  ? 78  LEU C O   1 
ATOM   5116 C  CB  . LEU C 1 82  ? -29.431 7.742   31.159  1   38.5   ? 78  LEU C CB  1 
ATOM   5117 C  CG  . LEU C 1 82  ? -30.038 6.479   31.776  1   39.05  ? 78  LEU C CG  1 
ATOM   5118 C  CD1 . LEU C 1 82  ? -29.269 6.044   32.991  1   39.75  ? 78  LEU C CD1 1 
ATOM   5119 C  CD2 . LEU C 1 82  ? -31.478 6.708   32.111  1   39.82  ? 78  LEU C CD2 1 
ATOM   5120 N  N   . VAL C 1 83  ? -27.515 8.423   28.321  1   28.87  ? 79  VAL C N   1 
ATOM   5121 C  CA  . VAL C 1 83  ? -27.227 9.424   27.308  1   27.78  ? 79  VAL C CA  1 
ATOM   5122 C  C   . VAL C 1 83  ? -28.522 9.772   26.579  1   28.63  ? 79  VAL C C   1 
ATOM   5123 O  O   . VAL C 1 83  ? -29.122 8.909   25.94   1   27.82  ? 79  VAL C O   1 
ATOM   5124 C  CB  . VAL C 1 83  ? -26.141 8.957   26.326  1   25.01  ? 79  VAL C CB  1 
ATOM   5125 C  CG1 . VAL C 1 83  ? -25.696 10.09   25.424  1   25.29  ? 79  VAL C CG1 1 
ATOM   5126 C  CG2 . VAL C 1 83  ? -24.957 8.382   27.069  1   25.8   ? 79  VAL C CG2 1 
ATOM   5127 N  N   . PHE C 1 84  ? -28.936 11.043  26.703  1   28.89  ? 80  PHE C N   1 
ATOM   5128 C  CA  . PHE C 1 84  ? -30.149 11.561  26.081  1   29.63  ? 80  PHE C CA  1 
ATOM   5129 C  C   . PHE C 1 84  ? -29.826 12.608  25.022  1   28.5   ? 80  PHE C C   1 
ATOM   5130 O  O   . PHE C 1 84  ? -28.798 13.287  25.113  1   26.26  ? 80  PHE C O   1 
ATOM   5131 C  CB  . PHE C 1 84  ? -31.031 12.258  27.124  1   30.62  ? 80  PHE C CB  1 
ATOM   5132 C  CG  . PHE C 1 84  ? -31.719 11.365  28.113  1   31.62  ? 80  PHE C CG  1 
ATOM   5133 C  CD1 . PHE C 1 84  ? -32.926 10.768  27.803  1   34.28  ? 80  PHE C CD1 1 
ATOM   5134 C  CD2 . PHE C 1 84  ? -31.162 11.118  29.358  1   32.16  ? 80  PHE C CD2 1 
ATOM   5135 C  CE1 . PHE C 1 84  ? -33.566 9.935   28.725  1   33.83  ? 80  PHE C CE1 1 
ATOM   5136 C  CE2 . PHE C 1 84  ? -31.806 10.294  30.271  1   30.1   ? 80  PHE C CE2 1 
ATOM   5137 C  CZ  . PHE C 1 84  ? -33.007 9.718   29.957  1   30.76  ? 80  PHE C CZ  1 
ATOM   5138 N  N   . GLU C 1 85  ? -30.739 12.779  24.06   1   28.03  ? 81  GLU C N   1 
ATOM   5139 C  CA  . GLU C 1 85  ? -30.66  13.914  23.153  1   30.8   ? 81  GLU C CA  1 
ATOM   5140 C  C   . GLU C 1 85  ? -30.765 15.161  24.027  1   29.32  ? 81  GLU C C   1 
ATOM   5141 O  O   . GLU C 1 85  ? -31.49  15.159  25.017  1   29.47  ? 81  GLU C O   1 
ATOM   5142 C  CB  . GLU C 1 85  ? -31.766 13.891  22.075  1   32.08  ? 81  GLU C CB  1 
ATOM   5143 C  CG  . GLU C 1 85  ? -33.173 14.109  22.631  1   35.48  ? 81  GLU C CG  1 
ATOM   5144 C  CD  . GLU C 1 85  ? -34.256 14.259  21.581  1   36.51  ? 81  GLU C CD  1 
ATOM   5145 O  OE1 . GLU C 1 85  ? -34.169 15.175  20.73   1   37.51  ? 81  GLU C OE1 1 
ATOM   5146 O  OE2 . GLU C 1 85  ? -35.214 13.462  21.625  1   42.72  ? 81  GLU C OE2 1 
ATOM   5147 N  N   . PHE C 1 86  ? -30.01  16.209  23.685  1   27.27  ? 82  PHE C N   1 
ATOM   5148 C  CA  . PHE C 1 86  ? -30.082 17.468  24.412  1   27.58  ? 82  PHE C CA  1 
ATOM   5149 C  C   . PHE C 1 86  ? -31.192 18.345  23.841  1   27.34  ? 82  PHE C C   1 
ATOM   5150 O  O   . PHE C 1 86  ? -31.318 18.486  22.632  1   26.51  ? 82  PHE C O   1 
ATOM   5151 C  CB  . PHE C 1 86  ? -28.77  18.229  24.345  1   26.77  ? 82  PHE C CB  1 
ATOM   5152 C  CG  . PHE C 1 86  ? -28.842 19.607  24.936  1   28.27  ? 82  PHE C CG  1 
ATOM   5153 C  CD1 . PHE C 1 86  ? -28.893 19.787  26.311  1   28.26  ? 82  PHE C CD1 1 
ATOM   5154 C  CD2 . PHE C 1 86  ? -28.852 20.735  24.116  1   29.45  ? 82  PHE C CD2 1 
ATOM   5155 C  CE1 . PHE C 1 86  ? -28.961 21.066  26.858  1   30.15  ? 82  PHE C CE1 1 
ATOM   5156 C  CE2 . PHE C 1 86  ? -28.913 22.017  24.665  1   29.44  ? 82  PHE C CE2 1 
ATOM   5157 C  CZ  . PHE C 1 86  ? -28.98  22.174  26.031  1   31.53  ? 82  PHE C CZ  1 
ATOM   5158 N  N   . LEU C 1 87  ? -31.995 18.935  24.727  1   29.36  ? 83  LEU C N   1 
ATOM   5159 C  CA  . LEU C 1 87  ? -33.013 19.891  24.318  1   31.36  ? 83  LEU C CA  1 
ATOM   5160 C  C   . LEU C 1 87  ? -32.78  21.148  25.151  1   32.06  ? 83  LEU C C   1 
ATOM   5161 O  O   . LEU C 1 87  ? -32.52  21.062  26.346  1   28.48  ? 83  LEU C O   1 
ATOM   5162 C  CB  . LEU C 1 87  ? -34.404 19.305  24.493  1   30.58  ? 83  LEU C CB  1 
ATOM   5163 C  CG  . LEU C 1 87  ? -34.667 18.034  23.647  1   33.89  ? 83  LEU C CG  1 
ATOM   5164 C  CD1 . LEU C 1 87  ? -35.712 17.155  24.26   1   34     ? 83  LEU C CD1 1 
ATOM   5165 C  CD2 . LEU C 1 87  ? -35.112 18.373  22.246  1   35.91  ? 83  LEU C CD2 1 
ATOM   5166 N  N   . HIS C 1 88  ? -32.856 22.297  24.473  1   38.98  ? 84  HIS C N   1 
ATOM   5167 C  CA  . HIS C 1 88  ? -32.436 23.595  24.979  1   44.09  ? 84  HIS C CA  1 
ATOM   5168 C  C   . HIS C 1 88  ? -32.937 23.984  26.372  1   37.66  ? 84  HIS C C   1 
ATOM   5169 O  O   . HIS C 1 88  ? -32.16  24.473  27.192  1   37.44  ? 84  HIS C O   1 
ATOM   5170 C  CB  . HIS C 1 88  ? -32.96  24.639  23.963  1   47.24  ? 84  HIS C CB  1 
ATOM   5171 C  CG  . HIS C 1 88  ? -32.738 26.068  24.341  1   58.37  ? 84  HIS C CG  1 
ATOM   5172 N  ND1 . HIS C 1 88  ? -31.469 26.631  24.327  1   71.47  ? 84  HIS C ND1 1 
ATOM   5173 C  CD2 . HIS C 1 88  ? -33.633 27.016  24.69   1   62.25  ? 84  HIS C CD2 1 
ATOM   5174 C  CE1 . HIS C 1 88  ? -31.626 27.897  24.691  1   71.1   ? 84  HIS C CE1 1 
ATOM   5175 N  NE2 . HIS C 1 88  ? -32.918 28.171  24.921  1   73.04  ? 84  HIS C NE2 1 
ATOM   5176 N  N   . GLN C 1 89  ? -34.237 23.775  26.621  1   35.31  ? 85  GLN C N   1 
ATOM   5177 C  CA  . GLN C 1 89  ? -34.78  23.949  27.962  1   33.5   ? 85  GLN C CA  1 
ATOM   5178 C  C   . GLN C 1 89  ? -36.138 23.273  28.154  1   28.79  ? 85  GLN C C   1 
ATOM   5179 O  O   . GLN C 1 89  ? -36.637 22.591  27.27   1   30.06  ? 85  GLN C O   1 
ATOM   5180 C  CB  . GLN C 1 89  ? -34.869 25.458  28.332  1   38.18  ? 85  GLN C CB  1 
ATOM   5181 C  CG  . GLN C 1 89  ? -35.869 26.265  27.529  1   39.97  ? 85  GLN C CG  1 
ATOM   5182 C  CD  . GLN C 1 89  ? -35.887 27.705  27.976  1   42.06  ? 85  GLN C CD  1 
ATOM   5183 O  OE1 . GLN C 1 89  ? -35.201 28.12   28.928  1   39.33  ? 85  GLN C OE1 1 
ATOM   5184 N  NE2 . GLN C 1 89  ? -36.681 28.506  27.293  1   40.65  ? 85  GLN C NE2 1 
ATOM   5185 N  N   . ASP C 1 90  ? -36.705 23.44   29.356  1   27.74  ? 86  ASP C N   1 
ATOM   5186 C  CA  . ASP C 1 90  ? -38.012 22.91   29.695  1   27.51  ? 86  ASP C CA  1 
ATOM   5187 C  C   . ASP C 1 90  ? -39.102 23.984  29.651  1   28.19  ? 86  ASP C C   1 
ATOM   5188 O  O   . ASP C 1 90  ? -38.813 25.182  29.66   1   25.56  ? 86  ASP C O   1 
ATOM   5189 C  CB  . ASP C 1 90  ? -37.955 22.234  31.077  1   28.84  ? 86  ASP C CB  1 
ATOM   5190 C  CG  . ASP C 1 90  ? -37.827 23.183  32.251  1   27.69  ? 86  ASP C CG  1 
ATOM   5191 O  OD1 . ASP C 1 90  ? -38.758 23.948  32.491  1   27.57  ? 86  ASP C OD1 1 
ATOM   5192 O  OD2 . ASP C 1 90  ? -36.777 23.173  32.907  1   35.7   ? 86  ASP C OD2 1 
ATOM   5193 N  N   . LEU C 1 91  ? -40.359 23.523  29.62   1   27.99  ? 87  LEU C N   1 
ATOM   5194 C  CA  . LEU C 1 91  ? -41.502 24.379  29.351  1   30.35  ? 87  LEU C CA  1 
ATOM   5195 C  C   . LEU C 1 91  ? -41.727 25.374  30.482  1   29.83  ? 87  LEU C C   1 
ATOM   5196 O  O   . LEU C 1 91  ? -42.183 26.487  30.233  1   29.18  ? 87  LEU C O   1 
ATOM   5197 C  CB  . LEU C 1 91  ? -42.774 23.518  29.139  1   30.84  ? 87  LEU C CB  1 
ATOM   5198 C  CG  . LEU C 1 91  ? -44.043 24.293  28.812  1   32.36  ? 87  LEU C CG  1 
ATOM   5199 C  CD1 . LEU C 1 91  ? -43.917 25.023  27.483  1   33.19  ? 87  LEU C CD1 1 
ATOM   5200 C  CD2 . LEU C 1 91  ? -45.233 23.388  28.772  1   31.88  ? 87  LEU C CD2 1 
ATOM   5201 N  N   . LYS C 1 92  ? -41.387 24.97   31.711  1   29.54  ? 88  LYS C N   1 
ATOM   5202 C  CA  . LYS C 1 92  ? -41.519 25.842  32.868  1   30.8   ? 88  LYS C CA  1 
ATOM   5203 C  C   . LYS C 1 92  ? -40.63  27.077  32.737  1   30.11  ? 88  LYS C C   1 
ATOM   5204 O  O   . LYS C 1 92  ? -41.102 28.193  32.922  1   29.46  ? 88  LYS C O   1 
ATOM   5205 C  CB  . LYS C 1 92  ? -41.209 25.085  34.169  1   31.88  ? 88  LYS C CB  1 
ATOM   5206 C  CG  . LYS C 1 92  ? -41.321 25.931  35.411  1   37.11  ? 88  LYS C CG  1 
ATOM   5207 C  CD  . LYS C 1 92  ? -42.691 26.568  35.574  1   45.92  ? 88  LYS C CD  1 
ATOM   5208 C  CE  . LYS C 1 92  ? -42.725 27.458  36.804  1   52.07  ? 88  LYS C CE  1 
ATOM   5209 N  NZ  . LYS C 1 92  ? -43.938 28.304  36.84   1   56.52  ? 88  LYS C NZ  1 
ATOM   5210 N  N   . LYS C 1 93  ? -39.35  26.869  32.405  1   32.32  ? 89  LYS C N   1 
ATOM   5211 C  CA  . LYS C 1 93  ? -38.42  27.973  32.227  1   32.68  ? 89  LYS C CA  1 
ATOM   5212 C  C   . LYS C 1 93  ? -38.845 28.885  31.079  1   28.48  ? 89  LYS C C   1 
ATOM   5213 O  O   . LYS C 1 93  ? -38.752 30.113  31.186  1   26.89  ? 89  LYS C O   1 
ATOM   5214 C  CB  . LYS C 1 93  ? -36.996 27.457  31.97   1   38.17  ? 89  LYS C CB  1 
ATOM   5215 C  CG  . LYS C 1 93  ? -36.335 26.835  33.169  1   46.92  ? 89  LYS C CG  1 
ATOM   5216 C  CD  . LYS C 1 93  ? -34.885 26.399  32.86   1   57.21  ? 89  LYS C CD  1 
ATOM   5217 C  CE  . LYS C 1 93  ? -34.347 25.343  33.808  1   62     ? 89  LYS C CE  1 
ATOM   5218 N  NZ  . LYS C 1 93  ? -34.705 25.631  35.226  1   65.88  ? 89  LYS C NZ  1 
ATOM   5219 N  N   . PHE C 1 94  ? -39.312 28.261  29.989  1   25.07  ? 90  PHE C N   1 
ATOM   5220 C  CA  . PHE C 1 94  ? -39.819 28.99   28.84   1   27.25  ? 90  PHE C CA  1 
ATOM   5221 C  C   . PHE C 1 94  ? -41.011 29.877  29.215  1   27.49  ? 90  PHE C C   1 
ATOM   5222 O  O   . PHE C 1 94  ? -41.04  31.065  28.884  1   24.55  ? 90  PHE C O   1 
ATOM   5223 C  CB  . PHE C 1 94  ? -40.19  28.016  27.711  1   26.23  ? 90  PHE C CB  1 
ATOM   5224 C  CG  . PHE C 1 94  ? -40.741 28.701  26.491  1   26.16  ? 90  PHE C CG  1 
ATOM   5225 C  CD1 . PHE C 1 94  ? -39.967 29.602  25.77   1   26.37  ? 90  PHE C CD1 1 
ATOM   5226 C  CD2 . PHE C 1 94  ? -42.048 28.472  26.079  1   26.91  ? 90  PHE C CD2 1 
ATOM   5227 C  CE1 . PHE C 1 94  ? -40.488 30.253  24.655  1   26.6   ? 90  PHE C CE1 1 
ATOM   5228 C  CE2 . PHE C 1 94  ? -42.562 29.122  24.961  1   27.3   ? 90  PHE C CE2 1 
ATOM   5229 C  CZ  . PHE C 1 94  ? -41.779 30.011  24.263  1   27.03  ? 90  PHE C CZ  1 
ATOM   5230 N  N   . MET C 1 95  ? -41.977 29.299  29.931  1   26.82  ? 91  MET C N   1 
ATOM   5231 C  CA  . MET C 1 95  ? -43.119 30.059  30.419  1   30.67  ? 91  MET C CA  1 
ATOM   5232 C  C   . MET C 1 95  ? -42.696 31.244  31.288  1   29.85  ? 91  MET C C   1 
ATOM   5233 O  O   . MET C 1 95  ? -43.128 32.374  31.044  1   28.51  ? 91  MET C O   1 
ATOM   5234 C  CB  . MET C 1 95  ? -44.07  29.145  31.191  1   31.67  ? 91  MET C CB  1 
ATOM   5235 C  CG  . MET C 1 95  ? -45.004 28.391  30.271  1   33.64  ? 91  MET C CG  1 
ATOM   5236 S  SD  . MET C 1 95  ? -46.169 27.275  31.101  1   40.79  ? 91  MET C SD  1 
ATOM   5237 C  CE  . MET C 1 95  ? -45.166 26.458  32.208  1   34.59  ? 91  MET C CE  1 
ATOM   5238 N  N   . ASP C 1 96  ? -41.812 30.989  32.263  1   27.04  ? 92  ASP C N   1 
ATOM   5239 C  CA  . ASP C 1 96  ? -41.299 32.04   33.134  1   28.54  ? 92  ASP C CA  1 
ATOM   5240 C  C   . ASP C 1 96  ? -40.556 33.138  32.376  1   27.95  ? 92  ASP C C   1 
ATOM   5241 O  O   . ASP C 1 96  ? -40.733 34.319  32.664  1   28.49  ? 92  ASP C O   1 
ATOM   5242 C  CB  . ASP C 1 96  ? -40.355 31.46   34.201  1   29.19  ? 92  ASP C CB  1 
ATOM   5243 C  CG  . ASP C 1 96  ? -41.031 30.593  35.239  1   30.95  ? 92  ASP C CG  1 
ATOM   5244 O  OD1 . ASP C 1 96  ? -42.269 30.617  35.314  1   32.02  ? 92  ASP C OD1 1 
ATOM   5245 O  OD2 . ASP C 1 96  ? -40.321 29.878  35.96   1   37.38  ? 92  ASP C OD2 1 
ATOM   5246 N  N   . ALA C 1 97  ? -39.703 32.732  31.431  1   28.25  ? 93  ALA C N   1 
ATOM   5247 C  CA  . ALA C 1 97  ? -39.075 33.63   30.479  1   28.8   ? 93  ALA C CA  1 
ATOM   5248 C  C   . ALA C 1 97  ? -40.065 34.465  29.673  1   28.43  ? 93  ALA C C   1 
ATOM   5249 O  O   . ALA C 1 97  ? -39.778 35.611  29.336  1   26.37  ? 93  ALA C O   1 
ATOM   5250 C  CB  . ALA C 1 97  ? -38.225 32.815  29.518  1   30.03  ? 93  ALA C CB  1 
ATOM   5251 N  N   . SER C 1 98  ? -41.21  33.86   29.332  1   31.9   ? 94  SER C N   1 
ATOM   5252 C  CA  . SER C 1 98  ? -42.26  34.546  28.595  1   36.11  ? 94  SER C CA  1 
ATOM   5253 C  C   . SER C 1 98  ? -43.237 35.315  29.49   1   42.65  ? 94  SER C C   1 
ATOM   5254 O  O   . SER C 1 98  ? -44.394 35.5    29.119  1   45.59  ? 94  SER C O   1 
ATOM   5255 C  CB  . SER C 1 98  ? -43.04  33.546  27.742  1   34.14  ? 94  SER C CB  1 
ATOM   5256 O  OG  . SER C 1 98  ? -42.219 32.863  26.81   1   33.61  ? 94  SER C OG  1 
ATOM   5257 N  N   . ALA C 1 99  ? -42.777 35.753  30.668  1   48.42  ? 95  ALA C N   1 
ATOM   5258 C  CA  . ALA C 1 99  ? -43.654 36.381  31.644  1   50.85  ? 95  ALA C CA  1 
ATOM   5259 C  C   . ALA C 1 99  ? -44.232 37.691  31.117  1   47.87  ? 95  ALA C C   1 
ATOM   5260 O  O   . ALA C 1 99  ? -45.422 37.95   31.26   1   47.73  ? 95  ALA C O   1 
ATOM   5261 C  CB  . ALA C 1 99  ? -42.91  36.638  32.941  1   52.01  ? 95  ALA C CB  1 
ATOM   5262 N  N   . LEU C 1 100 ? -43.372 38.513  30.514  1   47.12  ? 96  LEU C N   1 
ATOM   5263 C  CA  . LEU C 1 100 ? -43.768 39.827  30.047  1   49.73  ? 96  LEU C CA  1 
ATOM   5264 C  C   . LEU C 1 100 ? -44.222 39.832  28.587  1   53.16  ? 96  LEU C C   1 
ATOM   5265 O  O   . LEU C 1 100 ? -44.983 40.715  28.2    1   56.33  ? 96  LEU C O   1 
ATOM   5266 C  CB  . LEU C 1 100 ? -42.582 40.784  30.242  1   52.57  ? 96  LEU C CB  1 
ATOM   5267 C  CG  . LEU C 1 100 ? -41.996 40.824  31.662  1   53.35  ? 96  LEU C CG  1 
ATOM   5268 C  CD1 . LEU C 1 100 ? -41.04  42.004  31.835  1   54.6   ? 96  LEU C CD1 1 
ATOM   5269 C  CD2 . LEU C 1 100 ? -43.077 40.892  32.714  1   52.83  ? 96  LEU C CD2 1 
ATOM   5270 N  N   . THR C 1 101 ? -43.768 38.856  27.785  1   48.4   ? 97  THR C N   1 
ATOM   5271 C  CA  . THR C 1 101 ? -44.077 38.847  26.362  1   42.44  ? 97  THR C CA  1 
ATOM   5272 C  C   . THR C 1 101 ? -45.27  37.974  25.967  1   39.92  ? 97  THR C C   1 
ATOM   5273 O  O   . THR C 1 101 ? -45.736 38.064  24.839  1   40.32  ? 97  THR C O   1 
ATOM   5274 C  CB  . THR C 1 101 ? -42.838 38.444  25.53   1   40.34  ? 97  THR C CB  1 
ATOM   5275 O  OG1 . THR C 1 101 ? -42.463 37.081  25.809  1   37.31  ? 97  THR C OG1 1 
ATOM   5276 C  CG2 . THR C 1 101 ? -41.655 39.37   25.768  1   39.19  ? 97  THR C CG2 1 
ATOM   5277 N  N   . GLY C 1 102 ? -45.771 37.142  26.885  1   38.55  ? 98  GLY C N   1 
ATOM   5278 C  CA  . GLY C 1 102 ? -46.764 36.142  26.524  1   38.6   ? 98  GLY C CA  1 
ATOM   5279 C  C   . GLY C 1 102 ? -46.242 35.097  25.539  1   35.96  ? 98  GLY C C   1 
ATOM   5280 O  O   . GLY C 1 102 ? -45.214 35.307  24.903  1   30.69  ? 98  GLY C O   1 
ATOM   5281 N  N   . ILE C 1 103 ? -46.933 33.951  25.487  1   36.37  ? 99  ILE C N   1 
ATOM   5282 C  CA  . ILE C 1 103 ? -46.684 32.924  24.49   1   36.47  ? 99  ILE C CA  1 
ATOM   5283 C  C   . ILE C 1 103 ? -47.739 33.069  23.394  1   34.69  ? 99  ILE C C   1 
ATOM   5284 O  O   . ILE C 1 103 ? -48.934 33.013  23.673  1   33.06  ? 99  ILE C O   1 
ATOM   5285 C  CB  . ILE C 1 103 ? -46.714 31.496  25.105  1   37.46  ? 99  ILE C CB  1 
ATOM   5286 C  CG1 . ILE C 1 103 ? -45.723 31.364  26.271  1   39.59  ? 99  ILE C CG1 1 
ATOM   5287 C  CG2 . ILE C 1 103 ? -46.444 30.427  24.051  1   38.73  ? 99  ILE C CG2 1 
ATOM   5288 C  CD1 . ILE C 1 103 ? -45.879 30.075  27.057  1   39.53  ? 99  ILE C CD1 1 
ATOM   5289 N  N   . PRO C 1 104 ? -47.354 33.213  22.107  1   31.13  ? 100 PRO C N   1 
ATOM   5290 C  CA  . PRO C 1 104 ? -48.346 33.291  21.035  1   29.42  ? 100 PRO C CA  1 
ATOM   5291 C  C   . PRO C 1 104 ? -49.183 32.014  20.938  1   27.75  ? 100 PRO C C   1 
ATOM   5292 O  O   . PRO C 1 104 ? -48.691 30.904  21.121  1   23.12  ? 100 PRO C O   1 
ATOM   5293 C  CB  . PRO C 1 104 ? -47.504 33.567  19.77   1   30.01  ? 100 PRO C CB  1 
ATOM   5294 C  CG  . PRO C 1 104 ? -46.119 33.932  20.264  1   30.01  ? 100 PRO C CG  1 
ATOM   5295 C  CD  . PRO C 1 104 ? -45.97  33.27   21.616  1   30.27  ? 100 PRO C CD  1 
ATOM   5296 N  N   . LEU C 1 105 ? -50.468 32.201  20.63   1   28.87  ? 101 LEU C N   1 
ATOM   5297 C  CA  . LEU C 1 105 ? -51.443 31.121  20.601  1   31.02  ? 101 LEU C CA  1 
ATOM   5298 C  C   . LEU C 1 105 ? -51.071 30.007  19.619  1   28.58  ? 101 LEU C C   1 
ATOM   5299 O  O   . LEU C 1 105 ? -51.205 28.835  19.964  1   33.03  ? 101 LEU C O   1 
ATOM   5300 C  CB  . LEU C 1 105 ? -52.843 31.725  20.28   1   35.66  ? 101 LEU C CB  1 
ATOM   5301 C  CG  . LEU C 1 105 ? -54.092 30.921  20.694  1   39.89  ? 101 LEU C CG  1 
ATOM   5302 C  CD1 . LEU C 1 105 ? -54.168 29.548  20.015  1   37.57  ? 101 LEU C CD1 1 
ATOM   5303 C  CD2 . LEU C 1 105 ? -54.165 30.796  22.222  1   44.48  ? 101 LEU C CD2 1 
ATOM   5304 N  N   . PRO C 1 106 ? -50.589 30.294  18.384  1   25.37  ? 102 PRO C N   1 
ATOM   5305 C  CA  . PRO C 1 106 ? -50.17  29.227  17.467  1   25.76  ? 102 PRO C CA  1 
ATOM   5306 C  C   . PRO C 1 106 ? -49.129 28.278  18.057  1   25.57  ? 102 PRO C C   1 
ATOM   5307 O  O   . PRO C 1 106 ? -49.168 27.079  17.797  1   22.66  ? 102 PRO C O   1 
ATOM   5308 C  CB  . PRO C 1 106 ? -49.603 29.982  16.245  1   25.5   ? 102 PRO C CB  1 
ATOM   5309 C  CG  . PRO C 1 106 ? -50.263 31.34   16.282  1   25.05  ? 102 PRO C CG  1 
ATOM   5310 C  CD  . PRO C 1 106 ? -50.478 31.636  17.778  1   26.39  ? 102 PRO C CD  1 
ATOM   5311 N  N   . LEU C 1 107 ? -48.208 28.819  18.862  1   26.91  ? 103 LEU C N   1 
ATOM   5312 C  CA  . LEU C 1 107 ? -47.191 28.004  19.502  1   29.23  ? 103 LEU C CA  1 
ATOM   5313 C  C   . LEU C 1 107 ? -47.767 27.166  20.643  1   27.22  ? 103 LEU C C   1 
ATOM   5314 O  O   . LEU C 1 107 ? -47.326 26.04   20.863  1   24.76  ? 103 LEU C O   1 
ATOM   5315 C  CB  . LEU C 1 107 ? -46.052 28.913  20.002  1   31.17  ? 103 LEU C CB  1 
ATOM   5316 C  CG  . LEU C 1 107 ? -44.786 28.2    20.481  1   32.65  ? 103 LEU C CG  1 
ATOM   5317 C  CD1 . LEU C 1 107 ? -44.096 27.48   19.336  1   30.98  ? 103 LEU C CD1 1 
ATOM   5318 C  CD2 . LEU C 1 107 ? -43.852 29.176  21.156  1   34.24  ? 103 LEU C CD2 1 
ATOM   5319 N  N   . ILE C 1 108 ? -48.75  27.719  21.367  1   28.97  ? 104 ILE C N   1 
ATOM   5320 C  CA  . ILE C 1 108 ? -49.448 26.97   22.405  1   30.26  ? 104 ILE C CA  1 
ATOM   5321 C  C   . ILE C 1 108 ? -50.174 25.777  21.783  1   30.31  ? 104 ILE C C   1 
ATOM   5322 O  O   . ILE C 1 108 ? -50.115 24.657  22.283  1   33.31  ? 104 ILE C O   1 
ATOM   5323 C  CB  . ILE C 1 108 ? -50.41  27.9    23.19   1   27.64  ? 104 ILE C CB  1 
ATOM   5324 C  CG1 . ILE C 1 108 ? -49.63  28.943  24      1   28.68  ? 104 ILE C CG1 1 
ATOM   5325 C  CG2 . ILE C 1 108 ? -51.373 27.099  24.07   1   26.12  ? 104 ILE C CG2 1 
ATOM   5326 C  CD1 . ILE C 1 108 ? -50.524 30.07   24.635  1   29.51  ? 104 ILE C CD1 1 
ATOM   5327 N  N   . LYS C 1 109 ? -50.865 26.042  20.672  1   30.65  ? 105 LYS C N   1 
ATOM   5328 C  CA  . LYS C 1 109 ? -51.576 25.009  19.939  1   30.51  ? 105 LYS C CA  1 
ATOM   5329 C  C   . LYS C 1 109 ? -50.64  23.919  19.421  1   27.74  ? 105 LYS C C   1 
ATOM   5330 O  O   . LYS C 1 109 ? -50.912 22.737  19.595  1   29.09  ? 105 LYS C O   1 
ATOM   5331 C  CB  . LYS C 1 109 ? -52.323 25.656  18.778  1   30.07  ? 105 LYS C CB  1 
ATOM   5332 C  CG  . LYS C 1 109 ? -53.356 24.777  18.124  1   30.95  ? 105 LYS C CG  1 
ATOM   5333 C  CD  . LYS C 1 109 ? -54.087 25.541  17.03   1   30.41  ? 105 LYS C CD  1 
ATOM   5334 C  CE  . LYS C 1 109 ? -55.056 26.551  17.594  1   29.28  ? 105 LYS C CE  1 
ATOM   5335 N  NZ  . LYS C 1 109 ? -55.517 27.482  16.548  1   30.62  ? 105 LYS C NZ  1 
ATOM   5336 N  N   . SER C 1 110 ? -49.558 24.335  18.755  1   27.44  ? 106 SER C N   1 
ATOM   5337 C  CA  . SER C 1 110 ? -48.545 23.415  18.265  1   27.97  ? 106 SER C CA  1 
ATOM   5338 C  C   . SER C 1 110 ? -48.03  22.521  19.389  1   27.81  ? 106 SER C C   1 
ATOM   5339 O  O   . SER C 1 110 ? -47.93  21.309  19.24   1   25.81  ? 106 SER C O   1 
ATOM   5340 C  CB  . SER C 1 110 ? -47.381 24.182  17.648  1   27.52  ? 106 SER C CB  1 
ATOM   5341 O  OG  . SER C 1 110 ? -46.296 23.333  17.316  1   26.46  ? 106 SER C OG  1 
ATOM   5342 N  N   . TYR C 1 111 ? -47.717 23.14   20.527  1   27.49  ? 107 TYR C N   1 
ATOM   5343 C  CA  . TYR C 1 111 ? -47.14  22.418  21.649  1   27.57  ? 107 TYR C CA  1 
ATOM   5344 C  C   . TYR C 1 111 ? -48.132 21.416  22.238  1   28.85  ? 107 TYR C C   1 
ATOM   5345 O  O   . TYR C 1 111 ? -47.767 20.275  22.506  1   27.45  ? 107 TYR C O   1 
ATOM   5346 C  CB  . TYR C 1 111 ? -46.674 23.379  22.744  1   26.17  ? 107 TYR C CB  1 
ATOM   5347 C  CG  . TYR C 1 111 ? -45.318 24.033  22.587  1   25.13  ? 107 TYR C CG  1 
ATOM   5348 C  CD1 . TYR C 1 111 ? -44.451 23.664  21.565  1   25.55  ? 107 TYR C CD1 1 
ATOM   5349 C  CD2 . TYR C 1 111 ? -44.9   25.022  23.47   1   24.48  ? 107 TYR C CD2 1 
ATOM   5350 C  CE1 . TYR C 1 111 ? -43.196 24.255  21.435  1   25.14  ? 107 TYR C CE1 1 
ATOM   5351 C  CE2 . TYR C 1 111 ? -43.665 25.635  23.339  1   24.3   ? 107 TYR C CE2 1 
ATOM   5352 C  CZ  . TYR C 1 111 ? -42.806 25.243  22.326  1   24.68  ? 107 TYR C CZ  1 
ATOM   5353 O  OH  . TYR C 1 111 ? -41.579 25.841  22.232  1   22.96  ? 107 TYR C OH  1 
ATOM   5354 N  N   . LEU C 1 112 ? -49.384 21.841  22.443  1   29.99  ? 108 LEU C N   1 
ATOM   5355 C  CA  . LEU C 1 112 ? -50.385 20.936  22.978  1   30.89  ? 108 LEU C CA  1 
ATOM   5356 C  C   . LEU C 1 112 ? -50.596 19.754  22.031  1   30.28  ? 108 LEU C C   1 
ATOM   5357 O  O   . LEU C 1 112 ? -50.702 18.616  22.483  1   30.28  ? 108 LEU C O   1 
ATOM   5358 C  CB  . LEU C 1 112 ? -51.708 21.685  23.239  1   30.81  ? 108 LEU C CB  1 
ATOM   5359 C  CG  . LEU C 1 112 ? -52.803 20.843  23.881  1   30.68  ? 108 LEU C CG  1 
ATOM   5360 C  CD1 . LEU C 1 112 ? -52.355 20.291  25.208  1   30.39  ? 108 LEU C CD1 1 
ATOM   5361 C  CD2 . LEU C 1 112 ? -54.034 21.618  24.036  1   31.39  ? 108 LEU C CD2 1 
ATOM   5362 N  N   . PHE C 1 113 ? -50.634 20.033  20.719  1   31.23  ? 109 PHE C N   1 
ATOM   5363 C  CA  . PHE C 1 113 ? -50.795 19.002  19.703  1   30.67  ? 109 PHE C CA  1 
ATOM   5364 C  C   . PHE C 1 113 ? -49.681 17.966  19.79   1   28.31  ? 109 PHE C C   1 
ATOM   5365 O  O   . PHE C 1 113 ? -49.927 16.764  19.737  1   28.55  ? 109 PHE C O   1 
ATOM   5366 C  CB  . PHE C 1 113 ? -50.815 19.639  18.296  1   32.56  ? 109 PHE C CB  1 
ATOM   5367 C  CG  . PHE C 1 113 ? -51.285 18.743  17.171  1   30.3   ? 109 PHE C CG  1 
ATOM   5368 C  CD1 . PHE C 1 113 ? -52.569 18.225  17.168  1   33.09  ? 109 PHE C CD1 1 
ATOM   5369 C  CD2 . PHE C 1 113 ? -50.455 18.456  16.101  1   30.74  ? 109 PHE C CD2 1 
ATOM   5370 C  CE1 . PHE C 1 113 ? -53.001 17.401  16.132  1   34.08  ? 109 PHE C CE1 1 
ATOM   5371 C  CE2 . PHE C 1 113 ? -50.895 17.642  15.052  1   31.59  ? 109 PHE C CE2 1 
ATOM   5372 C  CZ  . PHE C 1 113 ? -52.158 17.111  15.079  1   31.75  ? 109 PHE C CZ  1 
ATOM   5373 N  N   . GLN C 1 114 ? -48.448 18.45   19.927  1   27.68  ? 110 GLN C N   1 
ATOM   5374 C  CA  . GLN C 1 114 ? -47.295 17.577  20.027  1   28.75  ? 110 GLN C CA  1 
ATOM   5375 C  C   . GLN C 1 114 ? -47.325 16.765  21.318  1   29.55  ? 110 GLN C C   1 
ATOM   5376 O  O   . GLN C 1 114 ? -47.046 15.566  21.299  1   29.24  ? 110 GLN C O   1 
ATOM   5377 C  CB  . GLN C 1 114 ? -46.013 18.395  19.932  1   29.02  ? 110 GLN C CB  1 
ATOM   5378 C  CG  . GLN C 1 114 ? -45.734 18.911  18.524  1   29.45  ? 110 GLN C CG  1 
ATOM   5379 C  CD  . GLN C 1 114 ? -44.403 19.611  18.507  1   30.2   ? 110 GLN C CD  1 
ATOM   5380 O  OE1 . GLN C 1 114 ? -43.335 18.979  18.634  1   30.61  ? 110 GLN C OE1 1 
ATOM   5381 N  NE2 . GLN C 1 114 ? -44.444 20.938  18.395  1   27.55  ? 110 GLN C NE2 1 
ATOM   5382 N  N   . LEU C 1 115 ? -47.673 17.423  22.433  1   30.25  ? 111 LEU C N   1 
ATOM   5383 C  CA  . LEU C 1 115 ? -47.781 16.746  23.715  1   29.6   ? 111 LEU C CA  1 
ATOM   5384 C  C   . LEU C 1 115 ? -48.794 15.605  23.637  1   29.9   ? 111 LEU C C   1 
ATOM   5385 O  O   . LEU C 1 115 ? -48.544 14.517  24.147  1   28.01  ? 111 LEU C O   1 
ATOM   5386 C  CB  . LEU C 1 115 ? -48.171 17.734  24.803  1   28.52  ? 111 LEU C CB  1 
ATOM   5387 C  CG  . LEU C 1 115 ? -47.089 18.722  25.203  1   28.27  ? 111 LEU C CG  1 
ATOM   5388 C  CD1 . LEU C 1 115 ? -47.622 19.738  26.173  1   26.59  ? 111 LEU C CD1 1 
ATOM   5389 C  CD2 . LEU C 1 115 ? -45.883 17.992  25.802  1   29.25  ? 111 LEU C CD2 1 
ATOM   5390 N  N   . LEU C 1 116 ? -49.922 15.862  22.968  1   31.44  ? 112 LEU C N   1 
ATOM   5391 C  CA  . LEU C 1 116 ? -50.96  14.859  22.795  1   31.61  ? 112 LEU C CA  1 
ATOM   5392 C  C   . LEU C 1 116 ? -50.514 13.713  21.891  1   31.78  ? 112 LEU C C   1 
ATOM   5393 O  O   . LEU C 1 116 ? -50.902 12.574  22.114  1   33.73  ? 112 LEU C O   1 
ATOM   5394 C  CB  . LEU C 1 116 ? -52.213 15.515  22.229  1   31.95  ? 112 LEU C CB  1 
ATOM   5395 C  CG  . LEU C 1 116 ? -52.999 16.372  23.21   1   32.43  ? 112 LEU C CG  1 
ATOM   5396 C  CD1 . LEU C 1 116 ? -53.977 17.287  22.47   1   34.9   ? 112 LEU C CD1 1 
ATOM   5397 C  CD2 . LEU C 1 116 ? -53.761 15.503  24.198  1   31.46  ? 112 LEU C CD2 1 
ATOM   5398 N  N   . GLN C 1 117 ? -49.706 14.009  20.868  1   31.85  ? 113 GLN C N   1 
ATOM   5399 C  CA  . GLN C 1 117 ? -49.159 12.962  20.018  1   30.89  ? 113 GLN C CA  1 
ATOM   5400 C  C   . GLN C 1 117 ? -48.212 12.052  20.794  1   29.56  ? 113 GLN C C   1 
ATOM   5401 O  O   . GLN C 1 117 ? -48.259 10.834  20.649  1   28.41  ? 113 GLN C O   1 
ATOM   5402 C  CB  . GLN C 1 117 ? -48.425 13.553  18.817  1   32.04  ? 113 GLN C CB  1 
ATOM   5403 C  CG  . GLN C 1 117 ? -49.398 13.983  17.738  1   33.86  ? 113 GLN C CG  1 
ATOM   5404 C  CD  . GLN C 1 117 ? -48.683 14.502  16.542  1   37.7   ? 113 GLN C CD  1 
ATOM   5405 O  OE1 . GLN C 1 117 ? -48.158 15.619  16.534  1   41.14  ? 113 GLN C OE1 1 
ATOM   5406 N  NE2 . GLN C 1 117 ? -48.634 13.693  15.51   1   39.8   ? 113 GLN C NE2 1 
ATOM   5407 N  N   . GLY C 1 118 ? -47.343 12.665  21.601  1   28.36  ? 114 GLY C N   1 
ATOM   5408 C  CA  . GLY C 1 118 ? -46.447 11.912  22.457  1   28.4   ? 114 GLY C CA  1 
ATOM   5409 C  C   . GLY C 1 118 ? -47.212 11.021  23.432  1   29.26  ? 114 GLY C C   1 
ATOM   5410 O  O   . GLY C 1 118 ? -46.892 9.846   23.592  1   30.04  ? 114 GLY C O   1 
ATOM   5411 N  N   . LEU C 1 119 ? -48.239 11.597  24.066  1   30.49  ? 115 LEU C N   1 
ATOM   5412 C  CA  . LEU C 1 119 ? -48.996 10.901  25.092  1   30.72  ? 115 LEU C CA  1 
ATOM   5413 C  C   . LEU C 1 119 ? -49.837 9.768   24.503  1   29.02  ? 115 LEU C C   1 
ATOM   5414 O  O   . LEU C 1 119 ? -49.901 8.687   25.078  1   31.25  ? 115 LEU C O   1 
ATOM   5415 C  CB  . LEU C 1 119 ? -49.864 11.904  25.868  1   29.84  ? 115 LEU C CB  1 
ATOM   5416 C  CG  . LEU C 1 119 ? -50.617 11.319  27.058  1   30.59  ? 115 LEU C CG  1 
ATOM   5417 C  CD1 . LEU C 1 119 ? -49.671 10.756  28.089  1   31.55  ? 115 LEU C CD1 1 
ATOM   5418 C  CD2 . LEU C 1 119 ? -51.498 12.342  27.713  1   30.16  ? 115 LEU C CD2 1 
ATOM   5419 N  N   . ALA C 1 120 ? -50.461 10.008  23.346  1   29.62  ? 116 ALA C N   1 
ATOM   5420 C  CA  . ALA C 1 120 ? -51.19  8.969   22.633  1   29.71  ? 116 ALA C CA  1 
ATOM   5421 C  C   . ALA C 1 120 ? -50.302 7.762   22.336  1   30.93  ? 116 ALA C C   1 
ATOM   5422 O  O   . ALA C 1 120 ? -50.744 6.621   22.458  1   28.96  ? 116 ALA C O   1 
ATOM   5423 C  CB  . ALA C 1 120 ? -51.766 9.511   21.343  1   29.38  ? 116 ALA C CB  1 
ATOM   5424 N  N   . PHE C 1 121 ? -49.049 8.031   21.958  1   31.7   ? 117 PHE C N   1 
ATOM   5425 C  CA  . PHE C 1 121 ? -48.075 6.988   21.69   1   31.08  ? 117 PHE C CA  1 
ATOM   5426 C  C   . PHE C 1 121 ? -47.771 6.206   22.965  1   30.28  ? 117 PHE C C   1 
ATOM   5427 O  O   . PHE C 1 121 ? -47.711 4.988   22.923  1   35.43  ? 117 PHE C O   1 
ATOM   5428 C  CB  . PHE C 1 121 ? -46.8   7.589   21.06   1   31.35  ? 117 PHE C CB  1 
ATOM   5429 C  CG  . PHE C 1 121 ? -45.87  6.563   20.486  1   31.31  ? 117 PHE C CG  1 
ATOM   5430 C  CD1 . PHE C 1 121 ? -44.951 5.914   21.291  1   32.3   ? 117 PHE C CD1 1 
ATOM   5431 C  CD2 . PHE C 1 121 ? -45.946 6.201   19.144  1   30.84  ? 117 PHE C CD2 1 
ATOM   5432 C  CE1 . PHE C 1 121 ? -44.094 4.941   20.759  1   32.47  ? 117 PHE C CE1 1 
ATOM   5433 C  CE2 . PHE C 1 121 ? -45.082 5.231   18.613  1   32.21  ? 117 PHE C CE2 1 
ATOM   5434 C  CZ  . PHE C 1 121 ? -44.164 4.611   19.423  1   31.49  ? 117 PHE C CZ  1 
ATOM   5435 N  N   . CYS C 1 122 ? -47.612 6.894   24.101  1   29.12  ? 118 CYS C N   1 
ATOM   5436 C  CA  . CYS C 1 122 ? -47.428 6.211   25.376  1   28.77  ? 118 CYS C CA  1 
ATOM   5437 C  C   . CYS C 1 122 ? -48.573 5.251   25.666  1   29.27  ? 118 CYS C C   1 
ATOM   5438 O  O   . CYS C 1 122 ? -48.345 4.076   25.933  1   31.44  ? 118 CYS C O   1 
ATOM   5439 C  CB  . CYS C 1 122 ? -47.261 7.195   26.524  1   27.97  ? 118 CYS C CB  1 
ATOM   5440 S  SG  . CYS C 1 122 ? -45.707 8.089   26.491  1   27.5   ? 118 CYS C SG  1 
ATOM   5441 N  N   . HIS C 1 123 ? -49.796 5.778   25.605  1   30.85  ? 119 HIS C N   1 
ATOM   5442 C  CA  . HIS C 1 123 ? -50.985 5.022   25.964  1   29.05  ? 119 HIS C CA  1 
ATOM   5443 C  C   . HIS C 1 123 ? -51.233 3.872   24.991  1   28.22  ? 119 HIS C C   1 
ATOM   5444 O  O   . HIS C 1 123 ? -51.635 2.793   25.413  1   29.45  ? 119 HIS C O   1 
ATOM   5445 C  CB  . HIS C 1 123 ? -52.183 5.977   26.061  1   29.08  ? 119 HIS C CB  1 
ATOM   5446 C  CG  . HIS C 1 123 ? -52.076 6.961   27.19   1   29.26  ? 119 HIS C CG  1 
ATOM   5447 N  ND1 . HIS C 1 123 ? -52.971 8.004   27.33   1   29.09  ? 119 HIS C ND1 1 
ATOM   5448 C  CD2 . HIS C 1 123 ? -51.177 7.032   28.198  1   30.9   ? 119 HIS C CD2 1 
ATOM   5449 C  CE1 . HIS C 1 123 ? -52.592 8.675   28.413  1   29.2   ? 119 HIS C CE1 1 
ATOM   5450 N  NE2 . HIS C 1 123 ? -51.519 8.124   28.968  1   30.62  ? 119 HIS C NE2 1 
ATOM   5451 N  N   . SER C 1 124 ? -50.947 4.097   23.702  1   29.02  ? 120 SER C N   1 
ATOM   5452 C  CA  . SER C 1 124 ? -50.986 3.038   22.704  1   28.45  ? 120 SER C CA  1 
ATOM   5453 C  C   . SER C 1 124 ? -49.97  1.932   22.969  1   29.19  ? 120 SER C C   1 
ATOM   5454 O  O   . SER C 1 124 ? -50.131 0.826   22.474  1   26.2   ? 120 SER C O   1 
ATOM   5455 C  CB  . SER C 1 124 ? -50.719 3.592   21.318  1   28.82  ? 120 SER C CB  1 
ATOM   5456 O  OG  . SER C 1 124 ? -51.745 4.49    20.939  1   36.72  ? 120 SER C OG  1 
ATOM   5457 N  N   . HIS C 1 125 ? -48.909 2.258   23.722  1   33.69  ? 121 HIS C N   1 
ATOM   5458 C  CA  . HIS C 1 125 ? -47.895 1.286   24.103  1   34.17  ? 121 HIS C CA  1 
ATOM   5459 C  C   . HIS C 1 125 ? -47.928 0.948   25.593  1   29.99  ? 121 HIS C C   1 
ATOM   5460 O  O   . HIS C 1 125 ? -46.895 0.642   26.182  1   27.21  ? 121 HIS C O   1 
ATOM   5461 C  CB  . HIS C 1 125 ? -46.535 1.806   23.652  1   35.35  ? 121 HIS C CB  1 
ATOM   5462 C  CG  . HIS C 1 125 ? -46.448 1.93    22.159  1   35.99  ? 121 HIS C CG  1 
ATOM   5463 N  ND1 . HIS C 1 125 ? -47.204 2.855   21.466  1   36.57  ? 121 HIS C ND1 1 
ATOM   5464 C  CD2 . HIS C 1 125 ? -45.717 1.224   21.274  1   34.28  ? 121 HIS C CD2 1 
ATOM   5465 C  CE1 . HIS C 1 125 ? -46.892 2.701   20.186  1   37.41  ? 121 HIS C CE1 1 
ATOM   5466 N  NE2 . HIS C 1 125 ? -46.003 1.723   20.029  1   37.52  ? 121 HIS C NE2 1 
ATOM   5467 N  N   . ARG C 1 126 ? -49.145 0.967   26.158  1   29.45  ? 122 ARG C N   1 
ATOM   5468 C  CA  . ARG C 1 126 ? -49.445 0.655   27.552  1   29.59  ? 122 ARG C CA  1 
ATOM   5469 C  C   . ARG C 1 126 ? -48.491 1.246   28.599  1   29.45  ? 122 ARG C C   1 
ATOM   5470 O  O   . ARG C 1 126 ? -48.183 0.602   29.602  1   28.4   ? 122 ARG C O   1 
ATOM   5471 C  CB  . ARG C 1 126 ? -49.619 -0.885  27.712  1   28.15  ? 122 ARG C CB  1 
ATOM   5472 C  CG  . ARG C 1 126 ? -48.5   -1.795  27.147  1   27.48  ? 122 ARG C CG  1 
ATOM   5473 C  CD  . ARG C 1 126 ? -47.415 -2.114  28.189  1   29.17  ? 122 ARG C CD  1 
ATOM   5474 N  NE  . ARG C 1 126 ? -46.403 -3.037  27.685  1   28.6   ? 122 ARG C NE  1 
ATOM   5475 C  CZ  . ARG C 1 126 ? -45.228 -2.669  27.178  1   28.63  ? 122 ARG C CZ  1 
ATOM   5476 N  NH1 . ARG C 1 126 ? -44.958 -1.401  26.888  1   28.06  ? 122 ARG C NH1 1 
ATOM   5477 N  NH2 . ARG C 1 126 ? -44.317 -3.602  26.921  1   26.3   ? 122 ARG C NH2 1 
ATOM   5478 N  N   . VAL C 1 127 ? -48.102 2.514   28.411  1   28.66  ? 123 VAL C N   1 
ATOM   5479 C  CA  . VAL C 1 127 ? -47.32  3.24    29.406  1   30.37  ? 123 VAL C CA  1 
ATOM   5480 C  C   . VAL C 1 127 ? -48.072 4.459   29.938  1   27.73  ? 123 VAL C C   1 
ATOM   5481 O  O   . VAL C 1 127 ? -48.5   5.308   29.155  1   27.31  ? 123 VAL C O   1 
ATOM   5482 C  CB  . VAL C 1 127 ? -45.948 3.667   28.814  1   32.74  ? 123 VAL C CB  1 
ATOM   5483 C  CG1 . VAL C 1 127 ? -45.21  4.66    29.731  1   31.29  ? 123 VAL C CG1 1 
ATOM   5484 C  CG2 . VAL C 1 127 ? -45.088 2.434   28.505  1   33.05  ? 123 VAL C CG2 1 
ATOM   5485 N  N   . LEU C 1 128 ? -48.23  4.527   31.269  1   25.21  ? 124 LEU C N   1 
ATOM   5486 C  CA  . LEU C 1 128 ? -48.641 5.754   31.938  1   26.77  ? 124 LEU C CA  1 
ATOM   5487 C  C   . LEU C 1 128 ? -47.396 6.563   32.294  1   26.3   ? 124 LEU C C   1 
ATOM   5488 O  O   . LEU C 1 128 ? -46.434 6.011   32.821  1   27.04  ? 124 LEU C O   1 
ATOM   5489 C  CB  . LEU C 1 128 ? -49.428 5.481   33.225  1   25.92  ? 124 LEU C CB  1 
ATOM   5490 C  CG  . LEU C 1 128 ? -50.698 4.651   33.116  1   26.82  ? 124 LEU C CG  1 
ATOM   5491 C  CD1 . LEU C 1 128 ? -51.245 4.329   34.508  1   26.56  ? 124 LEU C CD1 1 
ATOM   5492 C  CD2 . LEU C 1 128 ? -51.744 5.36    32.267  1   26.95  ? 124 LEU C CD2 1 
ATOM   5493 N  N   . HIS C 1 129 ? -47.43  7.877   32.04   1   25.36  ? 125 HIS C N   1 
ATOM   5494 C  CA  . HIS C 1 129 ? -46.33  8.749   32.423  1   25.77  ? 125 HIS C CA  1 
ATOM   5495 C  C   . HIS C 1 129 ? -46.351 9.069   33.92   1   25.17  ? 125 HIS C C   1 
ATOM   5496 O  O   . HIS C 1 129 ? -45.369 8.848   34.622  1   23.65  ? 125 HIS C O   1 
ATOM   5497 C  CB  . HIS C 1 129 ? -46.34  10.031  31.585  1   25.81  ? 125 HIS C CB  1 
ATOM   5498 C  CG  . HIS C 1 129 ? -45.137 10.894  31.817  1   26.48  ? 125 HIS C CG  1 
ATOM   5499 N  ND1 . HIS C 1 129 ? -45.016 11.688  32.951  1   26.84  ? 125 HIS C ND1 1 
ATOM   5500 C  CD2 . HIS C 1 129 ? -44.041 11.064  31.041  1   27.95  ? 125 HIS C CD2 1 
ATOM   5501 C  CE1 . HIS C 1 129 ? -43.846 12.305  32.837  1   29.01  ? 125 HIS C CE1 1 
ATOM   5502 N  NE2 . HIS C 1 129 ? -43.226 11.957  31.693  1   31.08  ? 125 HIS C NE2 1 
ATOM   5503 N  N   . ARG C 1 130 ? -47.474 9.617   34.392  1   26.62  ? 126 ARG C N   1 
ATOM   5504 C  CA  . ARG C 1 130 ? -47.743 9.827   35.809  1   29.81  ? 126 ARG C CA  1 
ATOM   5505 C  C   . ARG C 1 130 ? -46.926 10.94   36.465  1   29.65  ? 126 ARG C C   1 
ATOM   5506 O  O   . ARG C 1 130 ? -46.902 11.033  37.688  1   30.31  ? 126 ARG C O   1 
ATOM   5507 C  CB  . ARG C 1 130 ? -47.537 8.521   36.604  1   28.41  ? 126 ARG C CB  1 
ATOM   5508 C  CG  . ARG C 1 130 ? -48.405 7.369   36.13   1   26.58  ? 126 ARG C CG  1 
ATOM   5509 C  CD  . ARG C 1 130 ? -48.493 6.281   37.179  1   25.4   ? 126 ARG C CD  1 
ATOM   5510 N  NE  . ARG C 1 130 ? -47.186 5.695   37.455  1   25.42  ? 126 ARG C NE  1 
ATOM   5511 C  CZ  . ARG C 1 130 ? -46.95  4.792   38.394  1   26.28  ? 126 ARG C CZ  1 
ATOM   5512 N  NH1 . ARG C 1 130 ? -47.931 4.264   39.106  1   26.33  ? 126 ARG C NH1 1 
ATOM   5513 N  NH2 . ARG C 1 130 ? -45.698 4.403   38.623  1   26.54  ? 126 ARG C NH2 1 
ATOM   5514 N  N   . ASP C 1 131 ? -46.275 11.794  35.665  1   29.82  ? 127 ASP C N   1 
ATOM   5515 C  CA  . ASP C 1 131 ? -45.656 12.992  36.208  1   31.73  ? 127 ASP C CA  1 
ATOM   5516 C  C   . ASP C 1 131 ? -45.562 14.083  35.148  1   30.81  ? 127 ASP C C   1 
ATOM   5517 O  O   . ASP C 1 131 ? -44.527 14.726  34.985  1   31.58  ? 127 ASP C O   1 
ATOM   5518 C  CB  . ASP C 1 131 ? -44.267 12.706  36.806  1   32.12  ? 127 ASP C CB  1 
ATOM   5519 C  CG  . ASP C 1 131 ? -43.835 13.737  37.854  1   33.29  ? 127 ASP C CG  1 
ATOM   5520 O  OD1 . ASP C 1 131 ? -44.724 14.495  38.365  1   33.87  ? 127 ASP C OD1 1 
ATOM   5521 O  OD2 . ASP C 1 131 ? -42.611 13.81   38.144  1   32.97  ? 127 ASP C OD2 1 
ATOM   5522 N  N   . LEU C 1 132 ? -46.67  14.311  34.449  1   30.26  ? 128 LEU C N   1 
ATOM   5523 C  CA  . LEU C 1 132 ? -46.693 15.334  33.427  1   31.93  ? 128 LEU C CA  1 
ATOM   5524 C  C   . LEU C 1 132 ? -46.796 16.688  34.122  1   32.29  ? 128 LEU C C   1 
ATOM   5525 O  O   . LEU C 1 132 ? -47.748 16.968  34.839  1   39.94  ? 128 LEU C O   1 
ATOM   5526 C  CB  . LEU C 1 132 ? -47.833 15.089  32.457  1   29.74  ? 128 LEU C CB  1 
ATOM   5527 C  CG  . LEU C 1 132 ? -47.675 13.849  31.574  1   29.69  ? 128 LEU C CG  1 
ATOM   5528 C  CD1 . LEU C 1 132 ? -48.878 13.652  30.716  1   30.52  ? 128 LEU C CD1 1 
ATOM   5529 C  CD2 . LEU C 1 132 ? -46.443 13.932  30.674  1   29.27  ? 128 LEU C CD2 1 
ATOM   5530 N  N   . LYS C 1 133 ? -45.765 17.501  33.924  1   30.74  ? 129 LYS C N   1 
ATOM   5531 C  CA  . LYS C 1 133 ? -45.72  18.855  34.43   1   31.2   ? 129 LYS C CA  1 
ATOM   5532 C  C   . LYS C 1 133 ? -44.696 19.612  33.59   1   29.81  ? 129 LYS C C   1 
ATOM   5533 O  O   . LYS C 1 133 ? -43.858 18.997  32.933  1   29.93  ? 129 LYS C O   1 
ATOM   5534 C  CB  . LYS C 1 133 ? -45.371 18.853  35.891  1   32.86  ? 129 LYS C CB  1 
ATOM   5535 C  CG  . LYS C 1 133 ? -44.104 18.082  36.213  1   36.46  ? 129 LYS C CG  1 
ATOM   5536 C  CD  . LYS C 1 133 ? -43.76  18.264  37.668  1   38.44  ? 129 LYS C CD  1 
ATOM   5537 C  CE  . LYS C 1 133 ? -42.436 17.701  38.06   1   39.63  ? 129 LYS C CE  1 
ATOM   5538 N  NZ  . LYS C 1 133 ? -42.222 17.933  39.511  1   42.99  ? 129 LYS C NZ  1 
ATOM   5539 N  N   . PRO C 1 134 ? -44.748 20.96   33.552  1   29.29  ? 130 PRO C N   1 
ATOM   5540 C  CA  . PRO C 1 134 ? -43.926 21.723  32.611  1   29.4   ? 130 PRO C CA  1 
ATOM   5541 C  C   . PRO C 1 134 ? -42.424 21.469  32.727  1   27.09  ? 130 PRO C C   1 
ATOM   5542 O  O   . PRO C 1 134 ? -41.711 21.534  31.725  1   25.04  ? 130 PRO C O   1 
ATOM   5543 C  CB  . PRO C 1 134 ? -44.298 23.184  32.93   1   30.4   ? 130 PRO C CB  1 
ATOM   5544 C  CG  . PRO C 1 134 ? -45.613 23.125  33.632  1   31.55  ? 130 PRO C CG  1 
ATOM   5545 C  CD  . PRO C 1 134 ? -45.625 21.811  34.373  1   30.85  ? 130 PRO C CD  1 
ATOM   5546 N  N   . GLN C 1 135 ? -41.966 21.159  33.95   1   28.35  ? 131 GLN C N   1 
ATOM   5547 C  CA  . GLN C 1 135 ? -40.563 20.875  34.222  1   30.86  ? 131 GLN C CA  1 
ATOM   5548 C  C   . GLN C 1 135 ? -40.077 19.612  33.515  1   29.55  ? 131 GLN C C   1 
ATOM   5549 O  O   . GLN C 1 135 ? -38.879 19.438  33.344  1   32.56  ? 131 GLN C O   1 
ATOM   5550 C  CB  . GLN C 1 135 ? -40.306 20.7    35.733  1   30.74  ? 131 GLN C CB  1 
ATOM   5551 C  CG  . GLN C 1 135 ? -40.603 21.95   36.612  1   33.5   ? 131 GLN C CG  1 
ATOM   5552 C  CD  . GLN C 1 135 ? -42.092 22.201  36.946  1   35.37  ? 131 GLN C CD  1 
ATOM   5553 O  OE1 . GLN C 1 135 ? -43.024 21.477  36.534  1   33.38  ? 131 GLN C OE1 1 
ATOM   5554 N  NE2 . GLN C 1 135 ? -42.348 23.266  37.689  1   35.71  ? 131 GLN C NE2 1 
ATOM   5555 N  N   . ASN C 1 136 ? -41.013 18.723  33.148  1   28.79  ? 132 ASN C N   1 
ATOM   5556 C  CA  . ASN C 1 136 ? -40.692 17.462  32.497  1   27.46  ? 132 ASN C CA  1 
ATOM   5557 C  C   . ASN C 1 136 ? -41.022 17.455  31.007  1   26     ? 132 ASN C C   1 
ATOM   5558 O  O   . ASN C 1 136 ? -41.026 16.401  30.38   1   28.36  ? 132 ASN C O   1 
ATOM   5559 C  CB  . ASN C 1 136 ? -41.437 16.325  33.204  1   28.52  ? 132 ASN C CB  1 
ATOM   5560 C  CG  . ASN C 1 136 ? -40.931 16.061  34.611  1   28.36  ? 132 ASN C CG  1 
ATOM   5561 O  OD1 . ASN C 1 136 ? -39.858 16.524  35.013  1   28.54  ? 132 ASN C OD1 1 
ATOM   5562 N  ND2 . ASN C 1 136 ? -41.682 15.293  35.378  1   27.72  ? 132 ASN C ND2 1 
ATOM   5563 N  N   . LEU C 1 137 ? -41.312 18.634  30.445  1   25.34  ? 133 LEU C N   1 
ATOM   5564 C  CA  . LEU C 1 137 ? -41.559 18.778  29.02   1   24.77  ? 133 LEU C CA  1 
ATOM   5565 C  C   . LEU C 1 137 ? -40.453 19.659  28.446  1   26.57  ? 133 LEU C C   1 
ATOM   5566 O  O   . LEU C 1 137 ? -40.282 20.802  28.868  1   24.3   ? 133 LEU C O   1 
ATOM   5567 C  CB  . LEU C 1 137 ? -42.937 19.391  28.768  1   25.03  ? 133 LEU C CB  1 
ATOM   5568 C  CG  . LEU C 1 137 ? -44.083 18.764  29.556  1   25.33  ? 133 LEU C CG  1 
ATOM   5569 C  CD1 . LEU C 1 137 ? -45.383 19.486  29.286  1   27.82  ? 133 LEU C CD1 1 
ATOM   5570 C  CD2 . LEU C 1 137 ? -44.248 17.301  29.226  1   24.97  ? 133 LEU C CD2 1 
ATOM   5571 N  N   . LEU C 1 138 ? -39.705 19.107  27.482  1   27.9   ? 134 LEU C N   1 
ATOM   5572 C  CA  . LEU C 1 138 ? -38.523 19.764  26.944  1   27.2   ? 134 LEU C CA  1 
ATOM   5573 C  C   . LEU C 1 138 ? -38.805 20.3    25.545  1   26.17  ? 134 LEU C C   1 
ATOM   5574 O  O   . LEU C 1 138 ? -39.474 19.647  24.75   1   25.73  ? 134 LEU C O   1 
ATOM   5575 C  CB  . LEU C 1 138 ? -37.37  18.745  26.928  1   29.2   ? 134 LEU C CB  1 
ATOM   5576 C  CG  . LEU C 1 138 ? -37.115 18.043  28.277  1   30.26  ? 134 LEU C CG  1 
ATOM   5577 C  CD1 . LEU C 1 138 ? -36     17.069  28.167  1   34.28  ? 134 LEU C CD1 1 
ATOM   5578 C  CD2 . LEU C 1 138 ? -36.814 19.048  29.36   1   30.65  ? 134 LEU C CD2 1 
ATOM   5579 N  N   . ILE C 1 139 ? -38.292 21.5    25.261  1   25.68  ? 135 ILE C N   1 
ATOM   5580 C  CA  . ILE C 1 139 ? -38.436 22.123  23.958  1   27.09  ? 135 ILE C CA  1 
ATOM   5581 C  C   . ILE C 1 139 ? -37.056 22.322  23.343  1   28.16  ? 135 ILE C C   1 
ATOM   5582 O  O   . ILE C 1 139 ? -36.091 22.516  24.081  1   24.82  ? 135 ILE C O   1 
ATOM   5583 C  CB  . ILE C 1 139 ? -39.154 23.489  24.082  1   26.84  ? 135 ILE C CB  1 
ATOM   5584 C  CG1 . ILE C 1 139 ? -38.348 24.511  24.941  1   27.06  ? 135 ILE C CG1 1 
ATOM   5585 C  CG2 . ILE C 1 139 ? -40.538 23.327  24.624  1   27.64  ? 135 ILE C CG2 1 
ATOM   5586 C  CD1 . ILE C 1 139 ? -38.814 25.898  24.777  1   27.29  ? 135 ILE C CD1 1 
ATOM   5587 N  N   . ASN C 1 140 ? -36.989 22.331  22.003  1   29.01  ? 136 ASN C N   1 
ATOM   5588 C  CA  . ASN C 1 140 ? -35.795 22.782  21.3    1   31.17  ? 136 ASN C CA  1 
ATOM   5589 C  C   . ASN C 1 140 ? -36.053 24.12   20.607  1   33.6   ? 136 ASN C C   1 
ATOM   5590 O  O   . ASN C 1 140 ? -37.14  24.69   20.727  1   38.69  ? 136 ASN C O   1 
ATOM   5591 C  CB  . ASN C 1 140 ? -35.314 21.712  20.334  1   30.95  ? 136 ASN C CB  1 
ATOM   5592 C  CG  . ASN C 1 140 ? -36.258 21.447  19.184  1   33.04  ? 136 ASN C CG  1 
ATOM   5593 O  OD1 . ASN C 1 140 ? -37.154 22.226  18.855  1   33.02  ? 136 ASN C OD1 1 
ATOM   5594 N  ND2 . ASN C 1 140 ? -36.075 20.331  18.548  1   35.27  ? 136 ASN C ND2 1 
ATOM   5595 N  N   . THR C 1 141 ? -35.043 24.618  19.883  1   34.18  ? 137 THR C N   1 
ATOM   5596 C  CA  . THR C 1 141 ? -35.139 25.91   19.225  1   37.99  ? 137 THR C CA  1 
ATOM   5597 C  C   . THR C 1 141 ? -35.979 25.88   17.951  1   40.8   ? 137 THR C C   1 
ATOM   5598 O  O   . THR C 1 141 ? -36.332 26.932  17.419  1   42.81  ? 137 THR C O   1 
ATOM   5599 C  CB  . THR C 1 141 ? -33.728 26.455  18.917  1   39.98  ? 137 THR C CB  1 
ATOM   5600 O  OG1 . THR C 1 141 ? -33.084 25.61   17.982  1   38.77  ? 137 THR C OG1 1 
ATOM   5601 C  CG2 . THR C 1 141 ? -32.844 26.551  20.16   1   42.69  ? 137 THR C CG2 1 
ATOM   5602 N  N   . GLU C 1 142 ? -36.28  24.667  17.462  1   44.3   ? 138 GLU C N   1 
ATOM   5603 C  CA  . GLU C 1 142 ? -36.943 24.479  16.18   1   45.81  ? 138 GLU C CA  1 
ATOM   5604 C  C   . GLU C 1 142 ? -38.463 24.351  16.259  1   42.4   ? 138 GLU C C   1 
ATOM   5605 O  O   . GLU C 1 142 ? -39.128 24.278  15.228  1   45.57  ? 138 GLU C O   1 
ATOM   5606 C  CB  . GLU C 1 142 ? -36.361 23.242  15.483  1   47.57  ? 138 GLU C CB  1 
ATOM   5607 C  CG  . GLU C 1 142 ? -34.961 23.509  14.959  1   52.21  ? 138 GLU C CG  1 
ATOM   5608 C  CD  . GLU C 1 142 ? -34.579 22.645  13.787  1   60.22  ? 138 GLU C CD  1 
ATOM   5609 O  OE1 . GLU C 1 142 ? -34.598 21.404  13.946  1   60.9   ? 138 GLU C OE1 1 
ATOM   5610 O  OE2 . GLU C 1 142 ? -34.269 23.205  12.71   1   65.62  ? 138 GLU C OE2 1 
ATOM   5611 N  N   . GLY C 1 143 ? -39.004 24.315  17.478  1   32.67  ? 139 GLY C N   1 
ATOM   5612 C  CA  . GLY C 1 143 ? -40.44  24.328  17.679  1   29.7   ? 139 GLY C CA  1 
ATOM   5613 C  C   . GLY C 1 143 ? -41.03  22.99   18.102  1   28.25  ? 139 GLY C C   1 
ATOM   5614 O  O   . GLY C 1 143 ? -42.245 22.856  18.153  1   28.12  ? 139 GLY C O   1 
ATOM   5615 N  N   . ALA C 1 144 ? -40.175 22.011  18.414  1   29.22  ? 140 ALA C N   1 
ATOM   5616 C  CA  . ALA C 1 144 ? -40.636 20.736  18.95   1   31.25  ? 140 ALA C CA  1 
ATOM   5617 C  C   . ALA C 1 144 ? -40.773 20.781  20.474  1   28.37  ? 140 ALA C C   1 
ATOM   5618 O  O   . ALA C 1 144 ? -40.086 21.554  21.141  1   22.75  ? 140 ALA C O   1 
ATOM   5619 C  CB  . ALA C 1 144 ? -39.677 19.626  18.537  1   30.67  ? 140 ALA C CB  1 
ATOM   5620 N  N   . ILE C 1 145 ? -41.668 19.943  21.015  1   29.06  ? 141 ILE C N   1 
ATOM   5621 C  CA  . ILE C 1 145 ? -41.734 19.703  22.451  1   29.88  ? 141 ILE C CA  1 
ATOM   5622 C  C   . ILE C 1 145 ? -41.818 18.198  22.68   1   27.77  ? 141 ILE C C   1 
ATOM   5623 O  O   . ILE C 1 145 ? -42.435 17.496  21.888  1   27.05  ? 141 ILE C O   1 
ATOM   5624 C  CB  . ILE C 1 145 ? -42.92  20.497  23.107  1   33.2   ? 141 ILE C CB  1 
ATOM   5625 C  CG1 . ILE C 1 145 ? -42.889 20.418  24.647  1   31.18  ? 141 ILE C CG1 1 
ATOM   5626 C  CG2 . ILE C 1 145 ? -44.267 20.051  22.557  1   33.85  ? 141 ILE C CG2 1 
ATOM   5627 C  CD1 . ILE C 1 145 ? -43.815 21.39   25.36   1   30.1   ? 141 ILE C CD1 1 
ATOM   5628 N  N   . LYS C 1 146 ? -41.215 17.706  23.77   1   28.82  ? 142 LYS C N   1 
ATOM   5629 C  CA  . LYS C 1 146 ? -41.179 16.279  24.056  1   28.38  ? 142 LYS C CA  1 
ATOM   5630 C  C   . LYS C 1 146 ? -41.406 15.928  25.528  1   27.49  ? 142 LYS C C   1 
ATOM   5631 O  O   . LYS C 1 146 ? -40.936 16.627  26.422  1   26.95  ? 142 LYS C O   1 
ATOM   5632 C  CB  . LYS C 1 146 ? -39.819 15.7    23.647  1   28.68  ? 142 LYS C CB  1 
ATOM   5633 C  CG  . LYS C 1 146 ? -39.386 16.112  22.273  1   29.88  ? 142 LYS C CG  1 
ATOM   5634 C  CD  . LYS C 1 146 ? -38.241 15.309  21.714  1   29.28  ? 142 LYS C CD  1 
ATOM   5635 C  CE  . LYS C 1 146 ? -37.769 15.918  20.389  1   28.21  ? 142 LYS C CE  1 
ATOM   5636 N  NZ  . LYS C 1 146 ? -36.988 14.926  19.603  1   28.33  ? 142 LYS C NZ  1 
ATOM   5637 N  N   . LEU C 1 147 ? -42.104 14.809  25.758  1   26.43  ? 143 LEU C N   1 
ATOM   5638 C  CA  . LEU C 1 147 ? -42.277 14.269  27.092  1   26.93  ? 143 LEU C CA  1 
ATOM   5639 C  C   . LEU C 1 147 ? -40.921 13.785  27.595  1   29.23  ? 143 LEU C C   1 
ATOM   5640 O  O   . LEU C 1 147 ? -40.194 13.098  26.878  1   33.2   ? 143 LEU C O   1 
ATOM   5641 C  CB  . LEU C 1 147 ? -43.235 13.084  27.107  1   26.75  ? 143 LEU C CB  1 
ATOM   5642 C  CG  . LEU C 1 147 ? -44.575 13.174  26.411  1   28.97  ? 143 LEU C CG  1 
ATOM   5643 C  CD1 . LEU C 1 147 ? -45.508 12.094  26.918  1   30.53  ? 143 LEU C CD1 1 
ATOM   5644 C  CD2 . LEU C 1 147 ? -45.205 14.463  26.592  1   31.74  ? 143 LEU C CD2 1 
ATOM   5645 N  N   . ALA C 1 148 ? -40.587 14.121  28.838  1   28.32  ? 144 ALA C N   1 
ATOM   5646 C  CA  . ALA C 1 148 ? -39.357 13.626  29.435  1   32.07  ? 144 ALA C CA  1 
ATOM   5647 C  C   . ALA C 1 148 ? -39.614 13.134  30.858  1   29.52  ? 144 ALA C C   1 
ATOM   5648 O  O   . ALA C 1 148 ? -40.734 13.21   31.347  1   30.3   ? 144 ALA C O   1 
ATOM   5649 C  CB  . ALA C 1 148 ? -38.284 14.708  29.414  1   31.86  ? 144 ALA C CB  1 
ATOM   5650 N  N   . ASP C 1 149 ? -38.553 12.62   31.479  1   30.49  ? 145 ASP C N   1 
ATOM   5651 C  CA  . ASP C 1 149 ? -38.544 12.129  32.847  1   31     ? 145 ASP C CA  1 
ATOM   5652 C  C   . ASP C 1 149 ? -39.574 11.024  33.067  1   30.38  ? 145 ASP C C   1 
ATOM   5653 O  O   . ASP C 1 149 ? -40.619 11.236  33.684  1   29.74  ? 145 ASP C O   1 
ATOM   5654 C  CB  . ASP C 1 149 ? -38.725 13.281  33.832  1   36.28  ? 145 ASP C CB  1 
ATOM   5655 C  CG  . ASP C 1 149 ? -38.177 12.994  35.223  1   42.07  ? 145 ASP C CG  1 
ATOM   5656 O  OD1 . ASP C 1 149 ? -38.181 11.791  35.646  1   46.36  ? 145 ASP C OD1 1 
ATOM   5657 O  OD2 . ASP C 1 149 ? -37.776 13.956  35.901  1   53.16  ? 145 ASP C OD2 1 
ATOM   5658 N  N   . PHE C 1 150 ? -39.239 9.83    32.564  1   31.77  ? 146 PHE C N   1 
ATOM   5659 C  CA  . PHE C 1 150 ? -40.08  8.656   32.703  1   29.6   ? 146 PHE C CA  1 
ATOM   5660 C  C   . PHE C 1 150 ? -39.776 7.822   33.951  1   30.1   ? 146 PHE C C   1 
ATOM   5661 O  O   . PHE C 1 150 ? -40.09  6.635   34.003  1   30.85  ? 146 PHE C O   1 
ATOM   5662 C  CB  . PHE C 1 150 ? -39.954 7.81    31.427  1   31.53  ? 146 PHE C CB  1 
ATOM   5663 C  CG  . PHE C 1 150 ? -40.766 8.334   30.279  1   29.2   ? 146 PHE C CG  1 
ATOM   5664 C  CD1 . PHE C 1 150 ? -40.387 9.477   29.612  1   29.16  ? 146 PHE C CD1 1 
ATOM   5665 C  CD2 . PHE C 1 150 ? -41.934 7.704   29.897  1   29.44  ? 146 PHE C CD2 1 
ATOM   5666 C  CE1 . PHE C 1 150 ? -41.148 9.966   28.559  1   29.61  ? 146 PHE C CE1 1 
ATOM   5667 C  CE2 . PHE C 1 150 ? -42.693 8.194   28.847  1   29.97  ? 146 PHE C CE2 1 
ATOM   5668 C  CZ  . PHE C 1 150 ? -42.295 9.32    28.179  1   30.08  ? 146 PHE C CZ  1 
ATOM   5669 N  N   . GLY C 1 151 ? -39.191 8.454   34.972  1   34.44  ? 147 GLY C N   1 
ATOM   5670 C  CA  . GLY C 1 151 ? -38.845 7.773   36.21   1   36.13  ? 147 GLY C CA  1 
ATOM   5671 C  C   . GLY C 1 151 ? -40.063 7.289   36.994  1   36.76  ? 147 GLY C C   1 
ATOM   5672 O  O   . GLY C 1 151 ? -40.011 6.251   37.645  1   34.4   ? 147 GLY C O   1 
ATOM   5673 N  N   . LEU C 1 152 ? -41.165 8.044   36.898  1   34.76  ? 148 LEU C N   1 
ATOM   5674 C  CA  . LEU C 1 152 ? -42.399 7.701   37.584  1   34.16  ? 148 LEU C CA  1 
ATOM   5675 C  C   . LEU C 1 152 ? -43.373 6.925   36.705  1   30.37  ? 148 LEU C C   1 
ATOM   5676 O  O   . LEU C 1 152 ? -44.491 6.643   37.125  1   33.29  ? 148 LEU C O   1 
ATOM   5677 C  CB  . LEU C 1 152 ? -43.083 8.986   38.092  1   36.69  ? 148 LEU C CB  1 
ATOM   5678 C  CG  . LEU C 1 152 ? -42.504 9.582   39.387  1   41.74  ? 148 LEU C CG  1 
ATOM   5679 C  CD1 . LEU C 1 152 ? -43.399 10.694  39.915  1   46.68  ? 148 LEU C CD1 1 
ATOM   5680 C  CD2 . LEU C 1 152 ? -42.314 8.52    40.497  1   41.63  ? 148 LEU C CD2 1 
ATOM   5681 N  N   . ALA C 1 153 ? -42.939 6.557   35.498  1   29.16  ? 149 ALA C N   1 
ATOM   5682 C  CA  . ALA C 1 153 ? -43.809 5.912   34.528  1   27.87  ? 149 ALA C CA  1 
ATOM   5683 C  C   . ALA C 1 153 ? -44.046 4.451   34.898  1   29.4   ? 149 ALA C C   1 
ATOM   5684 O  O   . ALA C 1 153 ? -43.396 3.915   35.794  1   26.84  ? 149 ALA C O   1 
ATOM   5685 C  CB  . ALA C 1 153 ? -43.223 6.034   33.13   1   26.96  ? 149 ALA C CB  1 
ATOM   5686 N  N   . ARG C 1 154 ? -44.988 3.817   34.183  1   30.41  ? 150 ARG C N   1 
ATOM   5687 C  CA  . ARG C 1 154 ? -45.47  2.495   34.535  1   31.39  ? 150 ARG C CA  1 
ATOM   5688 C  C   . ARG C 1 154 ? -46.068 1.779   33.328  1   30.97  ? 150 ARG C C   1 
ATOM   5689 O  O   . ARG C 1 154 ? -46.906 2.341   32.627  1   34.24  ? 150 ARG C O   1 
ATOM   5690 C  CB  . ARG C 1 154 ? -46.526 2.666   35.628  1   31.8   ? 150 ARG C CB  1 
ATOM   5691 C  CG  . ARG C 1 154 ? -47.195 1.398   36.136  1   32.19  ? 150 ARG C CG  1 
ATOM   5692 C  CD  . ARG C 1 154 ? -46.265 0.618   36.996  1   33.06  ? 150 ARG C CD  1 
ATOM   5693 N  NE  . ARG C 1 154 ? -46.883 0.251   38.266  1   29.73  ? 150 ARG C NE  1 
ATOM   5694 C  CZ  . ARG C 1 154 ? -46.826 -0.957  38.796  1   28.22  ? 150 ARG C CZ  1 
ATOM   5695 N  NH1 . ARG C 1 154 ? -46.813 -2.043  38.042  1   28.22  ? 150 ARG C NH1 1 
ATOM   5696 N  NH2 . ARG C 1 154 ? -46.798 -1.082  40.12   1   29.21  ? 150 ARG C NH2 1 
ATOM   5697 N  N   . ALA C 1 155 ? -45.65  0.53    33.11   1   27.42  ? 151 ALA C N   1 
ATOM   5698 C  CA  . ALA C 1 155 ? -46.268 -0.305  32.098  1   26.99  ? 151 ALA C CA  1 
ATOM   5699 C  C   . ALA C 1 155 ? -47.535 -0.907  32.697  1   29.74  ? 151 ALA C C   1 
ATOM   5700 O  O   . ALA C 1 155 ? -47.457 -1.653  33.668  1   33.69  ? 151 ALA C O   1 
ATOM   5701 C  CB  . ALA C 1 155 ? -45.318 -1.391  31.638  1   25.7   ? 151 ALA C CB  1 
ATOM   5702 N  N   . PHE C 1 156 ? -48.699 -0.576  32.127  1   30.72  ? 152 PHE C N   1 
ATOM   5703 C  CA  . PHE C 1 156 ? -49.958 -1.086  32.653  1   30.05  ? 152 PHE C CA  1 
ATOM   5704 C  C   . PHE C 1 156 ? -50.487 -2.279  31.86   1   29.38  ? 152 PHE C C   1 
ATOM   5705 O  O   . PHE C 1 156 ? -50.057 -2.539  30.734  1   26.46  ? 152 PHE C O   1 
ATOM   5706 C  CB  . PHE C 1 156 ? -51.04  0.015   32.729  1   28.12  ? 152 PHE C CB  1 
ATOM   5707 C  CG  . PHE C 1 156 ? -51.51  0.685   31.452  1   25.49  ? 152 PHE C CG  1 
ATOM   5708 C  CD1 . PHE C 1 156 ? -50.835 1.765   30.929  1   25.75  ? 152 PHE C CD1 1 
ATOM   5709 C  CD2 . PHE C 1 156 ? -52.665 0.268   30.814  1   26.26  ? 152 PHE C CD2 1 
ATOM   5710 C  CE1 . PHE C 1 156 ? -51.294 2.411   29.777  1   24.8   ? 152 PHE C CE1 1 
ATOM   5711 C  CE2 . PHE C 1 156 ? -53.12  0.909   29.664  1   24.73  ? 152 PHE C CE2 1 
ATOM   5712 C  CZ  . PHE C 1 156 ? -52.424 1.973   29.146  1   24.72  ? 152 PHE C CZ  1 
ATOM   5713 N  N   . GLY C 1 157 ? -51.407 -3.015  32.495  1   29.43  ? 153 GLY C N   1 
ATOM   5714 C  CA  . GLY C 1 157 ? -52.17  -4.058  31.833  1   28.12  ? 153 GLY C CA  1 
ATOM   5715 C  C   . GLY C 1 157 ? -53.617 -3.613  31.635  1   28.19  ? 153 GLY C C   1 
ATOM   5716 O  O   . GLY C 1 157 ? -54.024 -2.563  32.151  1   31.4   ? 153 GLY C O   1 
ATOM   5717 N  N   . VAL C 1 158 ? -54.372 -4.427  30.885  1   25.82  ? 154 VAL C N   1 
ATOM   5718 C  CA  . VAL C 1 158 ? -55.749 -4.13   30.527  1   26.58  ? 154 VAL C CA  1 
ATOM   5719 C  C   . VAL C 1 158 ? -56.64  -5.261  31.035  1   26.97  ? 154 VAL C C   1 
ATOM   5720 O  O   . VAL C 1 158 ? -56.485 -6.395  30.586  1   27.62  ? 154 VAL C O   1 
ATOM   5721 C  CB  . VAL C 1 158 ? -55.898 -3.962  28.991  1   27.03  ? 154 VAL C CB  1 
ATOM   5722 C  CG1 . VAL C 1 158 ? -57.336 -3.616  28.612  1   27.2   ? 154 VAL C CG1 1 
ATOM   5723 C  CG2 . VAL C 1 158 ? -54.924 -2.93   28.431  1   27.01  ? 154 VAL C CG2 1 
ATOM   5724 N  N   . PRO C 1 159 ? -57.585 -5.022  31.98   1   27.41  ? 155 PRO C N   1 
ATOM   5725 C  CA  . PRO C 1 159 ? -57.757 -3.717  32.63   1   25.97  ? 155 PRO C CA  1 
ATOM   5726 C  C   . PRO C 1 159 ? -56.636 -3.363  33.609  1   26.34  ? 155 PRO C C   1 
ATOM   5727 O  O   . PRO C 1 159 ? -55.835 -4.209  33.997  1   27.02  ? 155 PRO C O   1 
ATOM   5728 C  CB  . PRO C 1 159 ? -59.098 -3.873  33.364  1   25.63  ? 155 PRO C CB  1 
ATOM   5729 C  CG  . PRO C 1 159 ? -59.202 -5.358  33.662  1   25.56  ? 155 PRO C CG  1 
ATOM   5730 C  CD  . PRO C 1 159 ? -58.54  -6.038  32.477  1   26.47  ? 155 PRO C CD  1 
ATOM   5731 N  N   . VAL C 1 160 ? -56.582 -2.091  34.005  1   27.05  ? 156 VAL C N   1 
ATOM   5732 C  CA  . VAL C 1 160 ? -55.6   -1.639  34.973  1   27.23  ? 156 VAL C CA  1 
ATOM   5733 C  C   . VAL C 1 160 ? -55.864 -2.318  36.31   1   27.36  ? 156 VAL C C   1 
ATOM   5734 O  O   . VAL C 1 160 ? -56.997 -2.687  36.611  1   25.13  ? 156 VAL C O   1 
ATOM   5735 C  CB  . VAL C 1 160 ? -55.585 -0.107  35.145  1   26.16  ? 156 VAL C CB  1 
ATOM   5736 C  CG1 . VAL C 1 160 ? -55.251 0.576   33.829  1   27.49  ? 156 VAL C CG1 1 
ATOM   5737 C  CG2 . VAL C 1 160 ? -56.903 0.415   35.707  1   26.17  ? 156 VAL C CG2 1 
ATOM   5738 N  N   . ARG C 1 161 ? -54.796 -2.494  37.092  1   29.44  ? 157 ARG C N   1 
ATOM   5739 C  CA  . ARG C 1 161 ? -54.933 -2.879  38.485  1   33.86  ? 157 ARG C CA  1 
ATOM   5740 C  C   . ARG C 1 161 ? -54.487 -1.701  39.352  1   32.32  ? 157 ARG C C   1 
ATOM   5741 O  O   . ARG C 1 161 ? -54.201 -0.617  38.831  1   30.65  ? 157 ARG C O   1 
ATOM   5742 C  CB  . ARG C 1 161 ? -54.177 -4.202  38.763  1   39.74  ? 157 ARG C CB  1 
ATOM   5743 C  CG  . ARG C 1 161 ? -52.661 -4.149  38.746  1   47.62  ? 157 ARG C CG  1 
ATOM   5744 C  CD  . ARG C 1 161 ? -52.081 -5.451  39.28   1   52.96  ? 157 ARG C CD  1 
ATOM   5745 N  NE  . ARG C 1 161 ? -50.645 -5.56   39.047  1   56.45  ? 157 ARG C NE  1 
ATOM   5746 C  CZ  . ARG C 1 161 ? -49.722 -4.819  39.651  1   61.21  ? 157 ARG C CZ  1 
ATOM   5747 N  NH1 . ARG C 1 161 ? -50.014 -4.055  40.691  1   62.65  ? 157 ARG C NH1 1 
ATOM   5748 N  NH2 . ARG C 1 161 ? -48.47  -4.854  39.206  1   61.09  ? 157 ARG C NH2 1 
ATOM   5749 N  N   . THR C 1 162 ? -54.478 -1.911  40.677  1   30.52  ? 158 THR C N   1 
ATOM   5750 C  CA  . THR C 1 162 ? -54.079 -0.877  41.619  1   33.08  ? 158 THR C CA  1 
ATOM   5751 C  C   . THR C 1 162 ? -52.575 -0.639  41.515  1   29.16  ? 158 THR C C   1 
ATOM   5752 O  O   . THR C 1 162 ? -51.787 -1.564  41.676  1   27.72  ? 158 THR C O   1 
ATOM   5753 C  CB  . THR C 1 162 ? -54.503 -1.252  43.051  1   34.32  ? 158 THR C CB  1 
ATOM   5754 O  OG1 . THR C 1 162 ? -55.922 -1.306  43.101  1   39.02  ? 158 THR C OG1 1 
ATOM   5755 C  CG2 . THR C 1 162 ? -54.005 -0.26   44.097  1   35.1   ? 158 THR C CG2 1 
ATOM   5756 N  N   . TYR C 1 163 ? -52.196 0.611   41.244  1   28.24  ? 159 TYR C N   1 
ATOM   5757 C  CA  . TYR C 1 163 ? -50.8   1.005   41.178  1   28.06  ? 159 TYR C CA  1 
ATOM   5758 C  C   . TYR C 1 163 ? -50.491 1.973   42.32   1   27.68  ? 159 TYR C C   1 
ATOM   5759 O  O   . TYR C 1 163 ? -51.342 2.224   43.17   1   29.9   ? 159 TYR C O   1 
ATOM   5760 C  CB  . TYR C 1 163 ? -50.485 1.613   39.796  1   29.4   ? 159 TYR C CB  1 
ATOM   5761 C  CG  . TYR C 1 163 ? -50.853 0.73    38.631  1   29.36  ? 159 TYR C CG  1 
ATOM   5762 C  CD1 . TYR C 1 163 ? -50.452 -0.596  38.586  1   34.44  ? 159 TYR C CD1 1 
ATOM   5763 C  CD2 . TYR C 1 163 ? -51.596 1.221   37.568  1   28.79  ? 159 TYR C CD2 1 
ATOM   5764 C  CE1 . TYR C 1 163 ? -50.796 -1.42   37.515  1   34.36  ? 159 TYR C CE1 1 
ATOM   5765 C  CE2 . TYR C 1 163 ? -51.939 0.412   36.488  1   30.83  ? 159 TYR C CE2 1 
ATOM   5766 C  CZ  . TYR C 1 163 ? -51.54  -0.913  36.466  1   33.56  ? 159 TYR C CZ  1 
ATOM   5767 O  OH  . TYR C 1 163 ? -51.88  -1.748  35.414  1   38.64  ? 159 TYR C OH  1 
HETATM 5768 N  N   . TPO C 1 164 ? -49.257 2.489   42.341  1   30.18  ? 160 TPO C N   1 
HETATM 5769 C  CA  . TPO C 1 164 ? -48.798 3.42    43.361  1   32.52  ? 160 TPO C CA  1 
HETATM 5770 C  CB  . TPO C 1 164 ? -47.368 3.885   43.042  1   32.83  ? 160 TPO C CB  1 
HETATM 5771 C  CG2 . TPO C 1 164 ? -46.775 4.794   44.098  1   31.77  ? 160 TPO C CG2 1 
HETATM 5772 O  OG1 . TPO C 1 164 ? -46.522 2.687   42.931  1   29.85  ? 160 TPO C OG1 1 
HETATM 5773 P  P   . TPO C 1 164 ? -45.881 2.255   41.513  1   26.84  ? 160 TPO C P   1 
HETATM 5774 O  O1P . TPO C 1 164 ? -47.051 2.029   40.581  1   30.36  ? 160 TPO C O1P 1 
HETATM 5775 O  O2P . TPO C 1 164 ? -45.087 1.009   41.786  1   25.78  ? 160 TPO C O2P 1 
HETATM 5776 O  O3P . TPO C 1 164 ? -45.014 3.399   41.049  1   27.05  ? 160 TPO C O3P 1 
HETATM 5777 C  C   . TPO C 1 164 ? -49.75  4.613   43.444  1   35.96  ? 160 TPO C C   1 
HETATM 5778 O  O   . TPO C 1 164 ? -50.083 5.201   42.414  1   35.91  ? 160 TPO C O   1 
ATOM   5779 N  N   . HIS C 1 165 ? -50.184 4.956   44.664  1   40.68  ? 161 HIS C N   1 
ATOM   5780 C  CA  . HIS C 1 165 ? -51.023 6.132   44.869  1   48.09  ? 161 HIS C CA  1 
ATOM   5781 C  C   . HIS C 1 165 ? -50.233 7.443   44.841  1   50.55  ? 161 HIS C C   1 
ATOM   5782 O  O   . HIS C 1 165 ? -50.695 8.426   44.265  1   51.47  ? 161 HIS C O   1 
ATOM   5783 C  CB  . HIS C 1 165 ? -51.835 6.044   46.185  1   54.71  ? 161 HIS C CB  1 
ATOM   5784 C  CG  . HIS C 1 165 ? -52.563 7.312   46.531  1   65.02  ? 161 HIS C CG  1 
ATOM   5785 N  ND1 . HIS C 1 165 ? -51.927 8.36    47.194  1   67.06  ? 161 HIS C ND1 1 
ATOM   5786 C  CD2 . HIS C 1 165 ? -53.847 7.673   46.29   1   69.15  ? 161 HIS C CD2 1 
ATOM   5787 C  CE1 . HIS C 1 165 ? -52.838 9.318   47.325  1   66.67  ? 161 HIS C CE1 1 
ATOM   5788 N  NE2 . HIS C 1 165 ? -54.012 8.944   46.798  1   65.72  ? 161 HIS C NE2 1 
ATOM   5789 N  N   . GLU C 1 166 ? -49.057 7.462   45.477  1   53.02  ? 162 GLU C N   1 
ATOM   5790 C  CA  . GLU C 1 166 ? -48.329 8.704   45.672  1   59.65  ? 162 GLU C CA  1 
ATOM   5791 C  C   . GLU C 1 166 ? -47.742 9.096   44.323  1   57.83  ? 162 GLU C C   1 
ATOM   5792 O  O   . GLU C 1 166 ? -46.529 8.982   44.151  1   62.59  ? 162 GLU C O   1 
ATOM   5793 C  CB  . GLU C 1 166 ? -47.183 8.578   46.721  1   65.69  ? 162 GLU C CB  1 
ATOM   5794 C  CG  . GLU C 1 166 ? -47.586 8.184   48.143  1   70.54  ? 162 GLU C CG  1 
ATOM   5795 C  CD  . GLU C 1 166 ? -48.104 6.759   48.301  1   72.73  ? 162 GLU C CD  1 
ATOM   5796 O  OE1 . GLU C 1 166 ? -47.476 5.832   47.736  1   67.29  ? 162 GLU C OE1 1 
ATOM   5797 O  OE2 . GLU C 1 166 ? -49.139 6.567   48.985  1   76.23  ? 162 GLU C OE2 1 
ATOM   5798 N  N   . VAL C 1 167 ? -48.595 9.528   43.379  1   52.44  ? 163 VAL C N   1 
ATOM   5799 C  CA  . VAL C 1 167 ? -48.155 9.83    42.024  1   48.82  ? 163 VAL C CA  1 
ATOM   5800 C  C   . VAL C 1 167 ? -48.697 11.172  41.535  1   44.6   ? 163 VAL C C   1 
ATOM   5801 O  O   . VAL C 1 167 ? -49.793 11.606  41.913  1   39.17  ? 163 VAL C O   1 
ATOM   5802 C  CB  . VAL C 1 167 ? -48.504 8.709   40.991  1   48.01  ? 163 VAL C CB  1 
ATOM   5803 C  CG1 . VAL C 1 167 ? -47.756 7.412   41.296  1   44.84  ? 163 VAL C CG1 1 
ATOM   5804 C  CG2 . VAL C 1 167 ? -50.007 8.474   40.909  1   49.01  ? 163 VAL C CG2 1 
ATOM   5805 N  N   . VAL C 1 168 ? -47.9   11.779  40.645  1   39.13  ? 164 VAL C N   1 
ATOM   5806 C  CA  . VAL C 1 168 ? -48.179 13.071  40.038  1   39     ? 164 VAL C CA  1 
ATOM   5807 C  C   . VAL C 1 168 ? -47.964 14.189  41.064  1   37.7   ? 164 VAL C C   1 
ATOM   5808 O  O   . VAL C 1 168 ? -48.497 14.159  42.175  1   37.14  ? 164 VAL C O   1 
ATOM   5809 C  CB  . VAL C 1 168 ? -49.597 13.189  39.383  1   39.74  ? 164 VAL C CB  1 
ATOM   5810 C  CG1 . VAL C 1 168 ? -49.649 14.386  38.427  1   37.57  ? 164 VAL C CG1 1 
ATOM   5811 C  CG2 . VAL C 1 168 ? -50.021 11.909  38.649  1   40.54  ? 164 VAL C CG2 1 
ATOM   5812 N  N   . THR C 1 169 ? -47.167 15.186  40.672  1   35.45  ? 165 THR C N   1 
ATOM   5813 C  CA  . THR C 1 169 ? -47.016 16.399  41.458  1   36.66  ? 165 THR C CA  1 
ATOM   5814 C  C   . THR C 1 169 ? -48.399 17.001  41.717  1   34.14  ? 165 THR C C   1 
ATOM   5815 O  O   . THR C 1 169 ? -49.24  17.02   40.816  1   36.4   ? 165 THR C O   1 
ATOM   5816 C  CB  . THR C 1 169 ? -46.045 17.321  40.719  1   38.64  ? 165 THR C CB  1 
ATOM   5817 O  OG1 . THR C 1 169 ? -44.838 16.564  40.458  1   41.42  ? 165 THR C OG1 1 
ATOM   5818 C  CG2 . THR C 1 169 ? -45.75  18.602  41.494  1   35.85  ? 165 THR C CG2 1 
ATOM   5819 N  N   . LEU C 1 170 ? -48.613 17.477  42.952  1   29.14  ? 166 LEU C N   1 
ATOM   5820 C  CA  . LEU C 1 170 ? -49.93  17.824  43.468  1   30.02  ? 166 LEU C CA  1 
ATOM   5821 C  C   . LEU C 1 170 ? -50.753 18.709  42.526  1   29.46  ? 166 LEU C C   1 
ATOM   5822 O  O   . LEU C 1 170 ? -51.913 18.407  42.231  1   31.49  ? 166 LEU C O   1 
ATOM   5823 C  CB  . LEU C 1 170 ? -49.755 18.52   44.846  1   29.64  ? 166 LEU C CB  1 
ATOM   5824 C  CG  . LEU C 1 170 ? -51.039 18.957  45.58   1   31.59  ? 166 LEU C CG  1 
ATOM   5825 C  CD1 . LEU C 1 170 ? -51.89  17.783  45.955  1   31.72  ? 166 LEU C CD1 1 
ATOM   5826 C  CD2 . LEU C 1 170 ? -50.724 19.777  46.869  1   31.17  ? 166 LEU C CD2 1 
ATOM   5827 N  N   . TRP C 1 171 ? -50.143 19.794  42.034  1   25.54  ? 167 TRP C N   1 
ATOM   5828 C  CA  . TRP C 1 171 ? -50.863 20.743  41.199  1   26.92  ? 167 TRP C CA  1 
ATOM   5829 C  C   . TRP C 1 171 ? -51.452 20.126  39.931  1   26.32  ? 167 TRP C C   1 
ATOM   5830 O  O   . TRP C 1 171 ? -52.379 20.689  39.353  1   25.95  ? 167 TRP C O   1 
ATOM   5831 C  CB  . TRP C 1 171 ? -49.965 21.914  40.786  1   27.11  ? 167 TRP C CB  1 
ATOM   5832 C  CG  . TRP C 1 171 ? -49.518 22.783  41.898  1   27.84  ? 167 TRP C CG  1 
ATOM   5833 C  CD1 . TRP C 1 171 ? -49.865 22.687  43.216  1   29.51  ? 167 TRP C CD1 1 
ATOM   5834 C  CD2 . TRP C 1 171 ? -48.625 23.889  41.797  1   29.83  ? 167 TRP C CD2 1 
ATOM   5835 N  NE1 . TRP C 1 171 ? -49.24  23.669  43.94   1   27.63  ? 167 TRP C NE1 1 
ATOM   5836 C  CE2 . TRP C 1 171 ? -48.474 24.428  43.093  1   29.76  ? 167 TRP C CE2 1 
ATOM   5837 C  CE3 . TRP C 1 171 ? -47.943 24.494  40.73   1   31.2   ? 167 TRP C CE3 1 
ATOM   5838 C  CZ2 . TRP C 1 171 ? -47.668 25.543  43.35   1   30.96  ? 167 TRP C CZ2 1 
ATOM   5839 C  CZ3 . TRP C 1 171 ? -47.139 25.594  40.99   1   31.98  ? 167 TRP C CZ3 1 
ATOM   5840 C  CH2 . TRP C 1 171 ? -47.008 26.104  42.284  1   32.67  ? 167 TRP C CH2 1 
ATOM   5841 N  N   . TYR C 1 172 ? -50.893 18.987  39.503  1   26.89  ? 168 TYR C N   1 
ATOM   5842 C  CA  . TYR C 1 172 ? -51.238 18.358  38.235  1   26.47  ? 168 TYR C CA  1 
ATOM   5843 C  C   . TYR C 1 172 ? -51.96  17.032  38.445  1   26.26  ? 168 TYR C C   1 
ATOM   5844 O  O   . TYR C 1 172 ? -52.193 16.302  37.485  1   26.02  ? 168 TYR C O   1 
ATOM   5845 C  CB  . TYR C 1 172 ? -49.941 18.18   37.383  1   25.9   ? 168 TYR C CB  1 
ATOM   5846 C  CG  . TYR C 1 172 ? -49.259 19.51   37.159  1   25.2   ? 168 TYR C CG  1 
ATOM   5847 C  CD1 . TYR C 1 172 ? -49.681 20.371  36.155  1   24.6   ? 168 TYR C CD1 1 
ATOM   5848 C  CD2 . TYR C 1 172 ? -48.275 19.961  38.027  1   24.68  ? 168 TYR C CD2 1 
ATOM   5849 C  CE1 . TYR C 1 172 ? -49.116 21.633  36      1   25.15  ? 168 TYR C CE1 1 
ATOM   5850 C  CE2 . TYR C 1 172 ? -47.694 21.213  37.874  1   24.81  ? 168 TYR C CE2 1 
ATOM   5851 C  CZ  . TYR C 1 172 ? -48.124 22.054  36.867  1   25.76  ? 168 TYR C CZ  1 
ATOM   5852 O  OH  . TYR C 1 172 ? -47.542 23.294  36.729  1   24.5   ? 168 TYR C OH  1 
ATOM   5853 N  N   . ARG C 1 173 ? -52.349 16.763  39.701  1   28.87  ? 169 ARG C N   1 
ATOM   5854 C  CA  . ARG C 1 173 ? -52.917 15.485  40.104  1   27.38  ? 169 ARG C CA  1 
ATOM   5855 C  C   . ARG C 1 173 ? -54.435 15.443  39.923  1   29.32  ? 169 ARG C C   1 
ATOM   5856 O  O   . ARG C 1 173 ? -55.149 16.341  40.377  1   26.94  ? 169 ARG C O   1 
ATOM   5857 C  CB  . ARG C 1 173 ? -52.559 15.225  41.567  1   27.33  ? 169 ARG C CB  1 
ATOM   5858 C  CG  . ARG C 1 173 ? -52.843 13.798  42.032  1   28.12  ? 169 ARG C CG  1 
ATOM   5859 C  CD  . ARG C 1 173 ? -52.424 13.588  43.473  1   27.68  ? 169 ARG C CD  1 
ATOM   5860 N  NE  . ARG C 1 173 ? -51.001 13.837  43.69   1   29.67  ? 169 ARG C NE  1 
ATOM   5861 C  CZ  . ARG C 1 173 ? -50.451 14.046  44.883  1   30.45  ? 169 ARG C CZ  1 
ATOM   5862 N  NH1 . ARG C 1 173 ? -51.168 14.02   45.997  1   29.87  ? 169 ARG C NH1 1 
ATOM   5863 N  NH2 . ARG C 1 173 ? -49.152 14.312  44.958  1   31.96  ? 169 ARG C NH2 1 
ATOM   5864 N  N   . ALA C 1 174 ? -54.911 14.374  39.263  1   29.75  ? 170 ALA C N   1 
ATOM   5865 C  CA  . ALA C 1 174 ? -56.317 14.22   38.925  1   29.57  ? 170 ALA C CA  1 
ATOM   5866 C  C   . ALA C 1 174 ? -57.175 13.985  40.163  1   29.58  ? 170 ALA C C   1 
ATOM   5867 O  O   . ALA C 1 174 ? -56.703 13.445  41.162  1   28.53  ? 170 ALA C O   1 
ATOM   5868 C  CB  . ALA C 1 174 ? -56.49  13.078  37.944  1   29.04  ? 170 ALA C CB  1 
ATOM   5869 N  N   . PRO C 1 175 ? -58.47  14.375  40.136  1   29.87  ? 171 PRO C N   1 
ATOM   5870 C  CA  . PRO C 1 175 ? -59.328 14.241  41.311  1   31.24  ? 171 PRO C CA  1 
ATOM   5871 C  C   . PRO C 1 175 ? -59.515 12.8    41.774  1   33.23  ? 171 PRO C C   1 
ATOM   5872 O  O   . PRO C 1 175 ? -59.663 12.568  42.97   1   37.68  ? 171 PRO C O   1 
ATOM   5873 C  CB  . PRO C 1 175 ? -60.654 14.866  40.884  1   31.44  ? 171 PRO C CB  1 
ATOM   5874 C  CG  . PRO C 1 175 ? -60.461 15.396  39.542  1   31.16  ? 171 PRO C CG  1 
ATOM   5875 C  CD  . PRO C 1 175 ? -59.166 14.943  38.978  1   30.82  ? 171 PRO C CD  1 
ATOM   5876 N  N   . GLU C 1 176 ? -59.495 11.842  40.831  1   33.17  ? 172 GLU C N   1 
ATOM   5877 C  CA  . GLU C 1 176 ? -59.642 10.437  41.179  1   31.77  ? 172 GLU C CA  1 
ATOM   5878 C  C   . GLU C 1 176 ? -58.501 9.969   42.081  1   30.65  ? 172 GLU C C   1 
ATOM   5879 O  O   . GLU C 1 176 ? -58.724 9.164   42.983  1   30.25  ? 172 GLU C O   1 
ATOM   5880 C  CB  . GLU C 1 176 ? -59.769 9.511   39.937  1   30.94  ? 172 GLU C CB  1 
ATOM   5881 C  CG  . GLU C 1 176 ? -58.673 9.6     38.885  1   30.22  ? 172 GLU C CG  1 
ATOM   5882 C  CD  . GLU C 1 176 ? -58.942 10.552  37.727  1   29.67  ? 172 GLU C CD  1 
ATOM   5883 O  OE1 . GLU C 1 176 ? -59.525 11.639  37.967  1   28.96  ? 172 GLU C OE1 1 
ATOM   5884 O  OE2 . GLU C 1 176 ? -58.538 10.225  36.586  1   25.46  ? 172 GLU C OE2 1 
ATOM   5885 N  N   . ILE C 1 177 ? -57.285 10.483  41.849  1   29.39  ? 173 ILE C N   1 
ATOM   5886 C  CA  . ILE C 1 177 ? -56.163 10.148  42.715  1   30.77  ? 173 ILE C CA  1 
ATOM   5887 C  C   . ILE C 1 177 ? -56.364 10.818  44.073  1   34.51  ? 173 ILE C C   1 
ATOM   5888 O  O   . ILE C 1 177 ? -56.231 10.173  45.114  1   35.7   ? 173 ILE C O   1 
ATOM   5889 C  CB  . ILE C 1 177 ? -54.795 10.494  42.102  1   30.21  ? 173 ILE C CB  1 
ATOM   5890 C  CG1 . ILE C 1 177 ? -54.575 9.777   40.763  1   32.06  ? 173 ILE C CG1 1 
ATOM   5891 C  CG2 . ILE C 1 177 ? -53.665 10.152  43.06   1   29.58  ? 173 ILE C CG2 1 
ATOM   5892 C  CD1 . ILE C 1 177 ? -53.361 10.308  39.955  1   34.82  ? 173 ILE C CD1 1 
ATOM   5893 N  N   . LEU C 1 178 ? -56.723 12.106  44.046  1   35.99  ? 174 LEU C N   1 
ATOM   5894 C  CA  . LEU C 1 178 ? -56.938 12.876  45.263  1   35.59  ? 174 LEU C CA  1 
ATOM   5895 C  C   . LEU C 1 178 ? -58.028 12.284  46.154  1   35.36  ? 174 LEU C C   1 
ATOM   5896 O  O   . LEU C 1 178 ? -57.915 12.347  47.371  1   36.55  ? 174 LEU C O   1 
ATOM   5897 C  CB  . LEU C 1 178 ? -57.314 14.331  44.914  1   35.4   ? 174 LEU C CB  1 
ATOM   5898 C  CG  . LEU C 1 178 ? -56.205 15.201  44.341  1   34.24  ? 174 LEU C CG  1 
ATOM   5899 C  CD1 . LEU C 1 178 ? -56.783 16.492  43.762  1   35.51  ? 174 LEU C CD1 1 
ATOM   5900 C  CD2 . LEU C 1 178 ? -55.168 15.502  45.387  1   33.63  ? 174 LEU C CD2 1 
ATOM   5901 N  N   . LEU C 1 179 ? -59.076 11.706  45.546  1   35.93  ? 175 LEU C N   1 
ATOM   5902 C  CA  . LEU C 1 179 ? -60.158 11.085  46.296  1   34.32  ? 175 LEU C CA  1 
ATOM   5903 C  C   . LEU C 1 179 ? -59.891 9.61    46.616  1   36.09  ? 175 LEU C C   1 
ATOM   5904 O  O   . LEU C 1 179 ? -60.787 8.911   47.082  1   38.18  ? 175 LEU C O   1 
ATOM   5905 C  CB  . LEU C 1 179 ? -61.471 11.217  45.509  1   36.96  ? 175 LEU C CB  1 
ATOM   5906 C  CG  . LEU C 1 179 ? -61.97  12.641  45.263  1   39.73  ? 175 LEU C CG  1 
ATOM   5907 C  CD1 . LEU C 1 179 ? -63.189 12.671  44.369  1   42.16  ? 175 LEU C CD1 1 
ATOM   5908 C  CD2 . LEU C 1 179 ? -62.327 13.321  46.527  1   41.05  ? 175 LEU C CD2 1 
ATOM   5909 N  N   . GLY C 1 180 ? -58.652 9.146   46.388  1   34.88  ? 176 GLY C N   1 
ATOM   5910 C  CA  . GLY C 1 180 ? -58.204 7.832   46.823  1   34.05  ? 176 GLY C CA  1 
ATOM   5911 C  C   . GLY C 1 180 ? -58.811 6.64    46.081  1   33.43  ? 176 GLY C C   1 
ATOM   5912 O  O   . GLY C 1 180 ? -58.973 5.569   46.661  1   34.15  ? 176 GLY C O   1 
ATOM   5913 N  N   . CYS C 1 181 ? -59.158 6.825   44.803  1   33.27  ? 177 CYS C N   1 
ATOM   5914 C  CA  . CYS C 1 181 ? -59.776 5.755   44.033  1   33.75  ? 177 CYS C CA  1 
ATOM   5915 C  C   . CYS C 1 181 ? -58.86  4.533   43.962  1   32.79  ? 177 CYS C C   1 
ATOM   5916 O  O   . CYS C 1 181 ? -57.642 4.657   43.991  1   29.76  ? 177 CYS C O   1 
ATOM   5917 C  CB  . CYS C 1 181 ? -60.203 6.244   42.65   1   35.83  ? 177 CYS C CB  1 
ATOM   5918 S  SG  . CYS C 1 181 ? -61.595 7.412   42.677  1   44.77  ? 177 CYS C SG  1 
ATOM   5919 N  N   . LYS C 1 182 ? -59.471 3.347   43.929  1   34.33  ? 178 LYS C N   1 
ATOM   5920 C  CA  . LYS C 1 182 ? -58.752 2.088   43.83   1   35.62  ? 178 LYS C CA  1 
ATOM   5921 C  C   . LYS C 1 182 ? -57.96  1.978   42.528  1   34.18  ? 178 LYS C C   1 
ATOM   5922 O  O   . LYS C 1 182 ? -56.851 1.445   42.512  1   34.37  ? 178 LYS C O   1 
ATOM   5923 C  CB  . LYS C 1 182 ? -59.765 0.922   43.921  1   40.68  ? 178 LYS C CB  1 
ATOM   5924 C  CG  . LYS C 1 182 ? -59.142 -0.472  44.065  1   44.78  ? 178 LYS C CG  1 
ATOM   5925 C  CD  . LYS C 1 182 ? -60.213 -1.56   44.221  1   47.76  ? 178 LYS C CD  1 
ATOM   5926 C  CE  . LYS C 1 182 ? -59.656 -2.935  44.526  1   48.09  ? 178 LYS C CE  1 
ATOM   5927 N  NZ  . LYS C 1 182 ? -60.745 -3.944  44.659  1   46.74  ? 178 LYS C NZ  1 
ATOM   5928 N  N   . TYR C 1 183 ? -58.566 2.464   41.441  1   30.79  ? 179 TYR C N   1 
ATOM   5929 C  CA  . TYR C 1 183 ? -58.008 2.334   40.108  1   30.53  ? 179 TYR C CA  1 
ATOM   5930 C  C   . TYR C 1 183 ? -57.94  3.708   39.458  1   30.72  ? 179 TYR C C   1 
ATOM   5931 O  O   . TYR C 1 183 ? -58.858 4.513   39.616  1   29.29  ? 179 TYR C O   1 
ATOM   5932 C  CB  . TYR C 1 183 ? -58.861 1.438   39.196  1   31.15  ? 179 TYR C CB  1 
ATOM   5933 C  CG  . TYR C 1 183 ? -59.114 0.035   39.696  1   31.5   ? 179 TYR C CG  1 
ATOM   5934 C  CD1 . TYR C 1 183 ? -58.068 -0.843  39.912  1   32.53  ? 179 TYR C CD1 1 
ATOM   5935 C  CD2 . TYR C 1 183 ? -60.407 -0.431  39.898  1   32.96  ? 179 TYR C CD2 1 
ATOM   5936 C  CE1 . TYR C 1 183 ? -58.296 -2.147  40.345  1   33.83  ? 179 TYR C CE1 1 
ATOM   5937 C  CE2 . TYR C 1 183 ? -60.648 -1.73   40.327  1   32.79  ? 179 TYR C CE2 1 
ATOM   5938 C  CZ  . TYR C 1 183 ? -59.589 -2.583  40.563  1   34.7   ? 179 TYR C CZ  1 
ATOM   5939 O  OH  . TYR C 1 183 ? -59.836 -3.865  40.997  1   38.89  ? 179 TYR C OH  1 
ATOM   5940 N  N   . TYR C 1 184 ? -56.838 3.951   38.74   1   30.46  ? 180 TYR C N   1 
ATOM   5941 C  CA  . TYR C 1 184 ? -56.744 5.057   37.803  1   29.16  ? 180 TYR C CA  1 
ATOM   5942 C  C   . TYR C 1 184 ? -56.092 4.554   36.517  1   28.67  ? 180 TYR C C   1 
ATOM   5943 O  O   . TYR C 1 184 ? -55.486 3.48    36.49   1   26.87  ? 180 TYR C O   1 
ATOM   5944 C  CB  . TYR C 1 184 ? -55.983 6.224   38.418  1   28.3   ? 180 TYR C CB  1 
ATOM   5945 C  CG  . TYR C 1 184 ? -54.554 5.914   38.792  1   27.83  ? 180 TYR C CG  1 
ATOM   5946 C  CD1 . TYR C 1 184 ? -53.557 5.868   37.83   1   26.21  ? 180 TYR C CD1 1 
ATOM   5947 C  CD2 . TYR C 1 184 ? -54.199 5.656   40.11   1   27.4   ? 180 TYR C CD2 1 
ATOM   5948 C  CE1 . TYR C 1 184 ? -52.238 5.581   38.17   1   26.11  ? 180 TYR C CE1 1 
ATOM   5949 C  CE2 . TYR C 1 184 ? -52.881 5.369   40.463  1   25.82  ? 180 TYR C CE2 1 
ATOM   5950 C  CZ  . TYR C 1 184 ? -51.902 5.335   39.489  1   26.13  ? 180 TYR C CZ  1 
ATOM   5951 O  OH  . TYR C 1 184 ? -50.607 5.029   39.829  1   28.03  ? 180 TYR C OH  1 
ATOM   5952 N  N   . SER C 1 185 ? -56.232 5.347   35.452  1   28.41  ? 181 SER C N   1 
ATOM   5953 C  CA  . SER C 1 185 ? -55.843 4.908   34.123  1   29.76  ? 181 SER C CA  1 
ATOM   5954 C  C   . SER C 1 185 ? -55.272 6.072   33.321  1   27.28  ? 181 SER C C   1 
ATOM   5955 O  O   . SER C 1 185 ? -54.837 7.074   33.893  1   28.5   ? 181 SER C O   1 
ATOM   5956 C  CB  . SER C 1 185 ? -57.051 4.278   33.419  1   31.94  ? 181 SER C CB  1 
ATOM   5957 O  OG  . SER C 1 185 ? -56.716 3.641   32.194  1   32.11  ? 181 SER C OG  1 
ATOM   5958 N  N   . THR C 1 186 ? -55.312 5.928   31.992  1   25.93  ? 182 THR C N   1 
ATOM   5959 C  CA  . THR C 1 186 ? -54.783 6.918   31.069  1   26.99  ? 182 THR C CA  1 
ATOM   5960 C  C   . THR C 1 186 ? -55.304 8.331   31.317  1   26.71  ? 182 THR C C   1 
ATOM   5961 O  O   . THR C 1 186 ? -54.605 9.297   31.04   1   29.48  ? 182 THR C O   1 
ATOM   5962 C  CB  . THR C 1 186 ? -55.075 6.483   29.633  1   25.76  ? 182 THR C CB  1 
ATOM   5963 O  OG1 . THR C 1 186 ? -56.47  6.28    29.472  1   25.77  ? 182 THR C OG1 1 
ATOM   5964 C  CG2 . THR C 1 186 ? -54.327 5.215   29.258  1   24.79  ? 182 THR C CG2 1 
ATOM   5965 N  N   . ALA C 1 187 ? -56.519 8.431   31.861  1   27.7   ? 183 ALA C N   1 
ATOM   5966 C  CA  . ALA C 1 187 ? -57.169 9.706   32.119  1   26.55  ? 183 ALA C CA  1 
ATOM   5967 C  C   . ALA C 1 187 ? -56.402 10.646  33.052  1   26.36  ? 183 ALA C C   1 
ATOM   5968 O  O   . ALA C 1 187 ? -56.558 11.858  32.946  1   27.05  ? 183 ALA C O   1 
ATOM   5969 C  CB  . ALA C 1 187 ? -58.583 9.454   32.66   1   25.63  ? 183 ALA C CB  1 
ATOM   5970 N  N   . VAL C 1 188 ? -55.573 10.102  33.953  1   28.4   ? 184 VAL C N   1 
ATOM   5971 C  CA  . VAL C 1 188 ? -54.795 10.938  34.856  1   28.53  ? 184 VAL C CA  1 
ATOM   5972 C  C   . VAL C 1 188 ? -53.744 11.739  34.09   1   29.6   ? 184 VAL C C   1 
ATOM   5973 O  O   . VAL C 1 188 ? -53.425 12.859  34.484  1   32.37  ? 184 VAL C O   1 
ATOM   5974 C  CB  . VAL C 1 188 ? -54.131 10.161  36.028  1   30.32  ? 184 VAL C CB  1 
ATOM   5975 C  CG1 . VAL C 1 188 ? -55.099 9.153   36.635  1   32.22  ? 184 VAL C CG1 1 
ATOM   5976 C  CG2 . VAL C 1 188 ? -52.827 9.493   35.605  1   32.39  ? 184 VAL C CG2 1 
ATOM   5977 N  N   . ASP C 1 189 ? -53.207 11.174  33      1   27.84  ? 185 ASP C N   1 
ATOM   5978 C  CA  . ASP C 1 189 ? -52.238 11.896  32.193  1   28     ? 185 ASP C CA  1 
ATOM   5979 C  C   . ASP C 1 189 ? -52.932 13.022  31.431  1   27.49  ? 185 ASP C C   1 
ATOM   5980 O  O   . ASP C 1 189 ? -52.353 14.094  31.26   1   26.56  ? 185 ASP C O   1 
ATOM   5981 C  CB  . ASP C 1 189 ? -51.477 10.964  31.221  1   27.21  ? 185 ASP C CB  1 
ATOM   5982 C  CG  . ASP C 1 189 ? -50.378 10.095  31.84   1   27.4   ? 185 ASP C CG  1 
ATOM   5983 O  OD1 . ASP C 1 189 ? -49.851 10.47   32.911  1   23.99  ? 185 ASP C OD1 1 
ATOM   5984 O  OD2 . ASP C 1 189 ? -50.072 9.01    31.262  1   28.51  ? 185 ASP C OD2 1 
ATOM   5985 N  N   . ILE C 1 190 ? -54.179 12.788  30.997  1   24.55  ? 186 ILE C N   1 
ATOM   5986 C  CA  . ILE C 1 190 ? -54.927 13.82   30.302  1   25.35  ? 186 ILE C CA  1 
ATOM   5987 C  C   . ILE C 1 190 ? -55.217 14.991  31.237  1   25.76  ? 186 ILE C C   1 
ATOM   5988 O  O   . ILE C 1 190 ? -55.085 16.149  30.837  1   28.37  ? 186 ILE C O   1 
ATOM   5989 C  CB  . ILE C 1 190 ? -56.214 13.246  29.647  1   27.58  ? 186 ILE C CB  1 
ATOM   5990 C  CG1 . ILE C 1 190 ? -55.865 12.348  28.427  1   27.78  ? 186 ILE C CG1 1 
ATOM   5991 C  CG2 . ILE C 1 190 ? -57.198 14.356  29.249  1   26.77  ? 186 ILE C CG2 1 
ATOM   5992 C  CD1 . ILE C 1 190 ? -55.27  13.09   27.238  1   27.33  ? 186 ILE C CD1 1 
ATOM   5993 N  N   . TRP C 1 191 ? -55.579 14.69   32.49   1   24.15  ? 187 TRP C N   1 
ATOM   5994 C  CA  . TRP C 1 191 ? -55.852 15.741  33.453  1   24.45  ? 187 TRP C CA  1 
ATOM   5995 C  C   . TRP C 1 191 ? -54.648 16.679  33.549  1   26.29  ? 187 TRP C C   1 
ATOM   5996 O  O   . TRP C 1 191 ? -54.791 17.895  33.461  1   25.87  ? 187 TRP C O   1 
ATOM   5997 C  CB  . TRP C 1 191 ? -56.231 15.155  34.833  1   23.81  ? 187 TRP C CB  1 
ATOM   5998 C  CG  . TRP C 1 191 ? -56.503 16.204  35.861  1   22.35  ? 187 TRP C CG  1 
ATOM   5999 C  CD1 . TRP C 1 191 ? -55.583 16.848  36.627  1   23.32  ? 187 TRP C CD1 1 
ATOM   6000 C  CD2 . TRP C 1 191 ? -57.778 16.795  36.181  1   22.56  ? 187 TRP C CD2 1 
ATOM   6001 N  NE1 . TRP C 1 191 ? -56.206 17.773  37.435  1   25.05  ? 187 TRP C NE1 1 
ATOM   6002 C  CE2 . TRP C 1 191 ? -57.553 17.765  37.173  1   22.72  ? 187 TRP C CE2 1 
ATOM   6003 C  CE3 . TRP C 1 191 ? -59.088 16.578  35.745  1   23.01  ? 187 TRP C CE3 1 
ATOM   6004 C  CZ2 . TRP C 1 191 ? -58.588 18.509  37.739  1   22.03  ? 187 TRP C CZ2 1 
ATOM   6005 C  CZ3 . TRP C 1 191 ? -60.109 17.32   36.3    1   23.43  ? 187 TRP C CZ3 1 
ATOM   6006 C  CH2 . TRP C 1 191 ? -59.856 18.273  37.285  1   22.42  ? 187 TRP C CH2 1 
ATOM   6007 N  N   . SER C 1 192 ? -53.457 16.102  33.726  1   26.25  ? 188 SER C N   1 
ATOM   6008 C  CA  . SER C 1 192 ? -52.24  16.884  33.828  1   26.66  ? 188 SER C CA  1 
ATOM   6009 C  C   . SER C 1 192 ? -52.054 17.808  32.621  1   26.07  ? 188 SER C C   1 
ATOM   6010 O  O   . SER C 1 192 ? -51.778 18.994  32.781  1   26.55  ? 188 SER C O   1 
ATOM   6011 C  CB  . SER C 1 192 ? -51.04  15.955  34.008  1   28.09  ? 188 SER C CB  1 
ATOM   6012 O  OG  . SER C 1 192 ? -51.174 15.106  35.142  1   29.19  ? 188 SER C OG  1 
ATOM   6013 N  N   . LEU C 1 193 ? -52.223 17.263  31.413  1   25.11  ? 189 LEU C N   1 
ATOM   6014 C  CA  . LEU C 1 193 ? -52.078 18.036  30.192  1   26.4   ? 189 LEU C CA  1 
ATOM   6015 C  C   . LEU C 1 193 ? -53.115 19.152  30.079  1   27.55  ? 189 LEU C C   1 
ATOM   6016 O  O   . LEU C 1 193 ? -52.825 20.209  29.526  1   26.92  ? 189 LEU C O   1 
ATOM   6017 C  CB  . LEU C 1 193 ? -52.192 17.129  28.953  1   29.13  ? 189 LEU C CB  1 
ATOM   6018 C  CG  . LEU C 1 193 ? -50.932 16.387  28.526  1   32.52  ? 189 LEU C CG  1 
ATOM   6019 C  CD1 . LEU C 1 193 ? -51.097 15.771  27.158  1   32.61  ? 189 LEU C CD1 1 
ATOM   6020 C  CD2 . LEU C 1 193 ? -49.713 17.3    28.511  1   33.55  ? 189 LEU C CD2 1 
ATOM   6021 N  N   . GLY C 1 194 ? -54.336 18.894  30.568  1   27.19  ? 190 GLY C N   1 
ATOM   6022 C  CA  . GLY C 1 194 ? -55.339 19.937  30.701  1   26.46  ? 190 GLY C CA  1 
ATOM   6023 C  C   . GLY C 1 194 ? -54.845 21.099  31.559  1   26.74  ? 190 GLY C C   1 
ATOM   6024 O  O   . GLY C 1 194 ? -54.934 22.258  31.157  1   29.46  ? 190 GLY C O   1 
ATOM   6025 N  N   . CYS C 1 195 ? -54.296 20.77   32.732  1   26.36  ? 191 CYS C N   1 
ATOM   6026 C  CA  . CYS C 1 195 ? -53.716 21.767  33.615  1   28.66  ? 191 CYS C CA  1 
ATOM   6027 C  C   . CYS C 1 195 ? -52.609 22.528  32.893  1   28.98  ? 191 CYS C C   1 
ATOM   6028 O  O   . CYS C 1 195 ? -52.485 23.743  33.043  1   28.17  ? 191 CYS C O   1 
ATOM   6029 C  CB  . CYS C 1 195 ? -53.196 21.131  34.903  1   29.32  ? 191 CYS C CB  1 
ATOM   6030 S  SG  . CYS C 1 195 ? -54.476 20.339  35.906  1   29.96  ? 191 CYS C SG  1 
ATOM   6031 N  N   . ILE C 1 196 ? -51.812 21.796  32.109  1   29.84  ? 192 ILE C N   1 
ATOM   6032 C  CA  . ILE C 1 196 ? -50.696 22.395  31.394  1   30.49  ? 192 ILE C CA  1 
ATOM   6033 C  C   . ILE C 1 196 ? -51.168 23.305  30.257  1   30.34  ? 192 ILE C C   1 
ATOM   6034 O  O   . ILE C 1 196 ? -50.616 24.39   30.074  1   30.14  ? 192 ILE C O   1 
ATOM   6035 C  CB  . ILE C 1 196 ? -49.71  21.299  30.941  1   30.25  ? 192 ILE C CB  1 
ATOM   6036 C  CG1 . ILE C 1 196 ? -49.052 20.675  32.189  1   29.76  ? 192 ILE C CG1 1 
ATOM   6037 C  CG2 . ILE C 1 196 ? -48.658 21.851  29.971  1   30.26  ? 192 ILE C CG2 1 
ATOM   6038 C  CD1 . ILE C 1 196 ? -48.411 19.402  32.024  1   32.63  ? 192 ILE C CD1 1 
ATOM   6039 N  N   . PHE C 1 197 ? -52.194 22.868  29.51   1   27.56  ? 193 PHE C N   1 
ATOM   6040 C  CA  . PHE C 1 197 ? -52.818 23.697  28.493  1   24.38  ? 193 PHE C CA  1 
ATOM   6041 C  C   . PHE C 1 197 ? -53.204 25.061  29.073  1   24.27  ? 193 PHE C C   1 
ATOM   6042 O  O   . PHE C 1 197 ? -52.778 26.094  28.581  1   21.9   ? 193 PHE C O   1 
ATOM   6043 C  CB  . PHE C 1 197 ? -54.025 22.958  27.926  1   24.57  ? 193 PHE C CB  1 
ATOM   6044 C  CG  . PHE C 1 197 ? -54.792 23.622  26.802  1   23.72  ? 193 PHE C CG  1 
ATOM   6045 C  CD1 . PHE C 1 197 ? -54.241 24.665  26.077  1   23.33  ? 193 PHE C CD1 1 
ATOM   6046 C  CD2 . PHE C 1 197 ? -56.072 23.203  26.478  1   25.11  ? 193 PHE C CD2 1 
ATOM   6047 C  CE1 . PHE C 1 197 ? -54.953 25.259  25.021  1   24.87  ? 193 PHE C CE1 1 
ATOM   6048 C  CE2 . PHE C 1 197 ? -56.788 23.811  25.443  1   25.27  ? 193 PHE C CE2 1 
ATOM   6049 C  CZ  . PHE C 1 197 ? -56.224 24.836  24.721  1   24.77  ? 193 PHE C CZ  1 
ATOM   6050 N  N   . ALA C 1 198 ? -53.982 25.053  30.158  1   25.45  ? 194 ALA C N   1 
ATOM   6051 C  CA  . ALA C 1 198 ? -54.387 26.28   30.822  1   26.84  ? 194 ALA C CA  1 
ATOM   6052 C  C   . ALA C 1 198 ? -53.186 27.138  31.208  1   29.46  ? 194 ALA C C   1 
ATOM   6053 O  O   . ALA C 1 198 ? -53.181 28.354  30.993  1   30.37  ? 194 ALA C O   1 
ATOM   6054 C  CB  . ALA C 1 198 ? -55.203 25.963  32.053  1   25.98  ? 194 ALA C CB  1 
ATOM   6055 N  N   . GLU C 1 199 ? -52.168 26.476  31.766  1   29.59  ? 195 GLU C N   1 
ATOM   6056 C  CA  . GLU C 1 199 ? -50.978 27.142  32.267  1   30.38  ? 195 GLU C CA  1 
ATOM   6057 C  C   . GLU C 1 199 ? -50.189 27.793  31.133  1   30.38  ? 195 GLU C C   1 
ATOM   6058 O  O   . GLU C 1 199 ? -49.654 28.885  31.298  1   31.66  ? 195 GLU C O   1 
ATOM   6059 C  CB  . GLU C 1 199 ? -50.126 26.128  33.051  1   29.27  ? 195 GLU C CB  1 
ATOM   6060 C  CG  . GLU C 1 199 ? -48.949 26.709  33.804  1   30     ? 195 GLU C CG  1 
ATOM   6061 C  CD  . GLU C 1 199 ? -48.297 25.783  34.821  1   31.65  ? 195 GLU C CD  1 
ATOM   6062 O  OE1 . GLU C 1 199 ? -48.896 24.736  35.16   1   32.79  ? 195 GLU C OE1 1 
ATOM   6063 O  OE2 . GLU C 1 199 ? -47.176 26.105  35.278  1   34.23  ? 195 GLU C OE2 1 
ATOM   6064 N  N   . MET C 1 200 ? -50.147 27.147  29.964  1   29.16  ? 196 MET C N   1 
ATOM   6065 C  CA  . MET C 1 200 ? -49.515 27.75   28.8    1   29.05  ? 196 MET C CA  1 
ATOM   6066 C  C   . MET C 1 200 ? -50.21  29.054  28.416  1   29.82  ? 196 MET C C   1 
ATOM   6067 O  O   . MET C 1 200 ? -49.542 30      28.006  1   33.52  ? 196 MET C O   1 
ATOM   6068 C  CB  . MET C 1 200 ? -49.493 26.773  27.613  1   29.11  ? 196 MET C CB  1 
ATOM   6069 C  CG  . MET C 1 200 ? -48.322 25.799  27.673  1   29.29  ? 196 MET C CG  1 
ATOM   6070 S  SD  . MET C 1 200 ? -48.1   24.867  26.151  1   28.56  ? 196 MET C SD  1 
ATOM   6071 C  CE  . MET C 1 200 ? -49.57  23.921  26.135  1   29.99  ? 196 MET C CE  1 
ATOM   6072 N  N   . VAL C 1 201 ? -51.539 29.107  28.577  1   29.66  ? 197 VAL C N   1 
ATOM   6073 C  CA  . VAL C 1 201 ? -52.322 30.268  28.179  1   29.99  ? 197 VAL C CA  1 
ATOM   6074 C  C   . VAL C 1 201 ? -52.173 31.445  29.142  1   30.39  ? 197 VAL C C   1 
ATOM   6075 O  O   . VAL C 1 201 ? -52.073 32.585  28.701  1   33.78  ? 197 VAL C O   1 
ATOM   6076 C  CB  . VAL C 1 201 ? -53.813 29.88   28.033  1   30.78  ? 197 VAL C CB  1 
ATOM   6077 C  CG1 . VAL C 1 201 ? -54.69  31.109  27.819  1   31.85  ? 197 VAL C CG1 1 
ATOM   6078 C  CG2 . VAL C 1 201 ? -54.018 28.86   26.913  1   29.57  ? 197 VAL C CG2 1 
ATOM   6079 N  N   . THR C 1 202 ? -52.188 31.158  30.454  1   31.34  ? 198 THR C N   1 
ATOM   6080 C  CA  . THR C 1 202 ? -52.111 32.173  31.497  1   28.09  ? 198 THR C CA  1 
ATOM   6081 C  C   . THR C 1 202 ? -50.709 32.347  32.083  1   28.27  ? 198 THR C C   1 
ATOM   6082 O  O   . THR C 1 202 ? -50.428 33.365  32.709  1   24.72  ? 198 THR C O   1 
ATOM   6083 C  CB  . THR C 1 202 ? -53.061 31.817  32.642  1   25.92  ? 198 THR C CB  1 
ATOM   6084 O  OG1 . THR C 1 202 ? -52.574 30.645  33.284  1   28.96  ? 198 THR C OG1 1 
ATOM   6085 C  CG2 . THR C 1 202 ? -54.473 31.569  32.186  1   25.5   ? 198 THR C CG2 1 
ATOM   6086 N  N   . ARG C 1 203 ? -49.855 31.324  31.906  1   31.41  ? 199 ARG C N   1 
ATOM   6087 C  CA  . ARG C 1 203 ? -48.528 31.264  32.506  1   34.75  ? 199 ARG C CA  1 
ATOM   6088 C  C   . ARG C 1 203 ? -48.552 31.234  34.036  1   32.48  ? 199 ARG C C   1 
ATOM   6089 O  O   . ARG C 1 203 ? -47.558 31.553  34.676  1   32.79  ? 199 ARG C O   1 
ATOM   6090 C  CB  . ARG C 1 203 ? -47.65  32.417  31.976  1   39.77  ? 199 ARG C CB  1 
ATOM   6091 C  CG  . ARG C 1 203 ? -47.082 32.141  30.599  1   39.63  ? 199 ARG C CG  1 
ATOM   6092 C  CD  . ARG C 1 203 ? -46.559 33.392  29.955  1   42.9   ? 199 ARG C CD  1 
ATOM   6093 N  NE  . ARG C 1 203 ? -47.647 34.232  29.468  1   47.59  ? 199 ARG C NE  1 
ATOM   6094 C  CZ  . ARG C 1 203 ? -47.884 35.478  29.855  1   47.22  ? 199 ARG C CZ  1 
ATOM   6095 N  NH1 . ARG C 1 203 ? -46.951 36.215  30.436  1   47.18  ? 199 ARG C NH1 1 
ATOM   6096 N  NH2 . ARG C 1 203 ? -49.094 35.994  29.664  1   48.48  ? 199 ARG C NH2 1 
ATOM   6097 N  N   . ARG C 1 204 ? -49.688 30.821  34.608  1   33.7   ? 200 ARG C N   1 
ATOM   6098 C  CA  . ARG C 1 204 ? -49.811 30.546  36.029  1   33.09  ? 200 ARG C CA  1 
ATOM   6099 C  C   . ARG C 1 204 ? -50.454 29.17   36.155  1   31.55  ? 200 ARG C C   1 
ATOM   6100 O  O   . ARG C 1 204 ? -51.293 28.802  35.332  1   32.74  ? 200 ARG C O   1 
ATOM   6101 C  CB  . ARG C 1 204 ? -50.69  31.575  36.751  1   35.22  ? 200 ARG C CB  1 
ATOM   6102 C  CG  . ARG C 1 204 ? -50.355 33.019  36.495  1   39.38  ? 200 ARG C CG  1 
ATOM   6103 C  CD  . ARG C 1 204 ? -51.44  33.906  37.039  1   43.45  ? 200 ARG C CD  1 
ATOM   6104 N  NE  . ARG C 1 204 ? -51.122 35.317  36.853  1   48.04  ? 200 ARG C NE  1 
ATOM   6105 C  CZ  . ARG C 1 204 ? -51.667 36.096  35.928  1   50.16  ? 200 ARG C CZ  1 
ATOM   6106 N  NH1 . ARG C 1 204 ? -52.55  35.627  35.061  1   53.43  ? 200 ARG C NH1 1 
ATOM   6107 N  NH2 . ARG C 1 204 ? -51.299 37.372  35.856  1   49.36  ? 200 ARG C NH2 1 
ATOM   6108 N  N   . ALA C 1 205 ? -50.065 28.418  37.191  1   28.6   ? 201 ALA C N   1 
ATOM   6109 C  CA  . ALA C 1 205 ? -50.649 27.111  37.439  1   26.55  ? 201 ALA C CA  1 
ATOM   6110 C  C   . ALA C 1 205 ? -52.15  27.274  37.657  1   25.52  ? 201 ALA C C   1 
ATOM   6111 O  O   . ALA C 1 205 ? -52.585 28.252  38.262  1   23.25  ? 201 ALA C O   1 
ATOM   6112 C  CB  . ALA C 1 205 ? -50.001 26.441  38.633  1   27.71  ? 201 ALA C CB  1 
ATOM   6113 N  N   . LEU C 1 206 ? -52.927 26.326  37.126  1   23.12  ? 202 LEU C N   1 
ATOM   6114 C  CA  . LEU C 1 206 ? -54.376 26.414  37.167  1   23.09  ? 202 LEU C CA  1 
ATOM   6115 C  C   . LEU C 1 206 ? -54.903 26.062  38.555  1   23.45  ? 202 LEU C C   1 
ATOM   6116 O  O   . LEU C 1 206 ? -55.835 26.701  39.029  1   24.53  ? 202 LEU C O   1 
ATOM   6117 C  CB  . LEU C 1 206 ? -54.983 25.48   36.104  1   23.12  ? 202 LEU C CB  1 
ATOM   6118 C  CG  . LEU C 1 206 ? -56.508 25.396  36.042  1   22.67  ? 202 LEU C CG  1 
ATOM   6119 C  CD1 . LEU C 1 206 ? -57.14  26.728  35.61   1   22.43  ? 202 LEU C CD1 1 
ATOM   6120 C  CD2 . LEU C 1 206 ? -56.944 24.261  35.129  1   21.81  ? 202 LEU C CD2 1 
ATOM   6121 N  N   . PHE C 1 207 ? -54.305 25.051  39.197  1   25.01  ? 203 PHE C N   1 
ATOM   6122 C  CA  . PHE C 1 207 ? -54.724 24.628  40.525  1   27.18  ? 203 PHE C CA  1 
ATOM   6123 C  C   . PHE C 1 207 ? -53.535 24.523  41.48   1   27.22  ? 203 PHE C C   1 
ATOM   6124 O  O   . PHE C 1 207 ? -53.066 23.424  41.759  1   29.74  ? 203 PHE C O   1 
ATOM   6125 C  CB  . PHE C 1 207 ? -55.439 23.283  40.434  1   26.51  ? 203 PHE C CB  1 
ATOM   6126 C  CG  . PHE C 1 207 ? -56.624 23.248  39.504  1   26.49  ? 203 PHE C CG  1 
ATOM   6127 C  CD1 . PHE C 1 207 ? -57.668 24.138  39.65   1   25.14  ? 203 PHE C CD1 1 
ATOM   6128 C  CD2 . PHE C 1 207 ? -56.712 22.301  38.508  1   27.16  ? 203 PHE C CD2 1 
ATOM   6129 C  CE1 . PHE C 1 207 ? -58.771 24.095  38.804  1   24.66  ? 203 PHE C CE1 1 
ATOM   6130 C  CE2 . PHE C 1 207 ? -57.817 22.255  37.667  1   26.69  ? 203 PHE C CE2 1 
ATOM   6131 C  CZ  . PHE C 1 207 ? -58.842 23.152  37.823  1   26.25  ? 203 PHE C CZ  1 
ATOM   6132 N  N   . PRO C 1 208 ? -52.996 25.656  41.989  1   26.39  ? 204 PRO C N   1 
ATOM   6133 C  CA  . PRO C 1 208 ? -51.803 25.638  42.839  1   27.77  ? 204 PRO C CA  1 
ATOM   6134 C  C   . PRO C 1 208 ? -52.098 25.388  44.318  1   27.09  ? 204 PRO C C   1 
ATOM   6135 O  O   . PRO C 1 208 ? -51.962 26.285  45.141  1   30.76  ? 204 PRO C O   1 
ATOM   6136 C  CB  . PRO C 1 208 ? -51.222 27.046  42.617  1   27.4   ? 204 PRO C CB  1 
ATOM   6137 C  CG  . PRO C 1 208 ? -52.434 27.922  42.428  1   26.91  ? 204 PRO C CG  1 
ATOM   6138 C  CD  . PRO C 1 208 ? -53.505 27.022  41.771  1   26.99  ? 204 PRO C CD  1 
ATOM   6139 N  N   . GLY C 1 209 ? -52.529 24.171  44.65   1   28.52  ? 205 GLY C N   1 
ATOM   6140 C  CA  . GLY C 1 209 ? -52.92  23.863  46.016  1   29.91  ? 205 GLY C CA  1 
ATOM   6141 C  C   . GLY C 1 209 ? -51.712 23.702  46.934  1   29.04  ? 205 GLY C C   1 
ATOM   6142 O  O   . GLY C 1 209 ? -50.652 23.299  46.477  1   28.3   ? 205 GLY C O   1 
ATOM   6143 N  N   . ASP C 1 210 ? -51.882 24.005  48.228  1   31.73  ? 206 ASP C N   1 
ATOM   6144 C  CA  . ASP C 1 210 ? -50.82  23.787  49.2    1   34.84  ? 206 ASP C CA  1 
ATOM   6145 C  C   . ASP C 1 210 ? -51.087 22.58   50.105  1   34.3   ? 206 ASP C C   1 
ATOM   6146 O  O   . ASP C 1 210 ? -50.359 22.359  51.068  1   33.04  ? 206 ASP C O   1 
ATOM   6147 C  CB  . ASP C 1 210 ? -50.515 25.085  49.999  1   35.3   ? 206 ASP C CB  1 
ATOM   6148 C  CG  . ASP C 1 210 ? -51.634 25.689  50.834  1   40.84  ? 206 ASP C CG  1 
ATOM   6149 O  OD1 . ASP C 1 210 ? -52.759 25.167  50.783  1   46.22  ? 206 ASP C OD1 1 
ATOM   6150 O  OD2 . ASP C 1 210 ? -51.374 26.666  51.56   1   45     ? 206 ASP C OD2 1 
ATOM   6151 N  N   . SER C 1 211 ? -52.098 21.771  49.761  1   32.48  ? 207 SER C N   1 
ATOM   6152 C  CA  . SER C 1 211 ? -52.363 20.512  50.441  1   32.74  ? 207 SER C CA  1 
ATOM   6153 C  C   . SER C 1 211 ? -53.358 19.694  49.618  1   32.43  ? 207 SER C C   1 
ATOM   6154 O  O   . SER C 1 211 ? -53.912 20.199  48.645  1   34.49  ? 207 SER C O   1 
ATOM   6155 C  CB  . SER C 1 211 ? -52.896 20.751  51.854  1   30.9   ? 207 SER C CB  1 
ATOM   6156 O  OG  . SER C 1 211 ? -54.192 21.323  51.839  1   31.19  ? 207 SER C OG  1 
ATOM   6157 N  N   . GLU C 1 212 ? -53.598 18.438  50.006  1   30.16  ? 208 GLU C N   1 
ATOM   6158 C  CA  . GLU C 1 212 ? -54.573 17.626  49.293  1   32.38  ? 208 GLU C CA  1 
ATOM   6159 C  C   . GLU C 1 212 ? -55.982 18.214  49.378  1   31     ? 208 GLU C C   1 
ATOM   6160 O  O   . GLU C 1 212 ? -56.676 18.318  48.371  1   30.02  ? 208 GLU C O   1 
ATOM   6161 C  CB  . GLU C 1 212 ? -54.516 16.175  49.778  1   34.61  ? 208 GLU C CB  1 
ATOM   6162 C  CG  . GLU C 1 212 ? -53.416 15.41   49.06   1   37.93  ? 208 GLU C CG  1 
ATOM   6163 C  CD  . GLU C 1 212 ? -52.994 14.104  49.69   1   41.83  ? 208 GLU C CD  1 
ATOM   6164 O  OE1 . GLU C 1 212 ? -53.831 13.18   49.78   1   42.54  ? 208 GLU C OE1 1 
ATOM   6165 O  OE2 . GLU C 1 212 ? -51.81  14.008  50.083  1   47.29  ? 208 GLU C OE2 1 
ATOM   6166 N  N   . ILE C 1 213 ? -56.396 18.623  50.58   1   32.58  ? 209 ILE C N   1 
ATOM   6167 C  CA  . ILE C 1 213 ? -57.703 19.237  50.762  1   32.29  ? 209 ILE C CA  1 
ATOM   6168 C  C   . ILE C 1 213 ? -57.809 20.565  50.002  1   28.51  ? 209 ILE C C   1 
ATOM   6169 O  O   . ILE C 1 213 ? -58.827 20.841  49.369  1   25.24  ? 209 ILE C O   1 
ATOM   6170 C  CB  . ILE C 1 213 ? -58.041 19.395  52.272  1   33.62  ? 209 ILE C CB  1 
ATOM   6171 C  CG1 . ILE C 1 213 ? -59.48  19.89   52.462  1   37     ? 209 ILE C CG1 1 
ATOM   6172 C  CG2 . ILE C 1 213 ? -57.063 20.299  53.02   1   34.66  ? 209 ILE C CG2 1 
ATOM   6173 C  CD1 . ILE C 1 213 ? -60.512 18.87   52.052  1   40.1   ? 209 ILE C CD1 1 
ATOM   6174 N  N   . ASP C 1 214 ? -56.745 21.374  50.047  1   24.68  ? 210 ASP C N   1 
ATOM   6175 C  CA  . ASP C 1 214 ? -56.734 22.648  49.353  1   24.82  ? 210 ASP C CA  1 
ATOM   6176 C  C   . ASP C 1 214 ? -56.748 22.449  47.84   1   23.55  ? 210 ASP C C   1 
ATOM   6177 O  O   . ASP C 1 214 ? -57.427 23.175  47.125  1   21.73  ? 210 ASP C O   1 
ATOM   6178 C  CB  . ASP C 1 214 ? -55.525 23.473  49.788  1   24.9   ? 210 ASP C CB  1 
ATOM   6179 C  CG  . ASP C 1 214 ? -55.449 24.828  49.155  1   24.65  ? 210 ASP C CG  1 
ATOM   6180 O  OD1 . ASP C 1 214 ? -56.396 25.62   49.337  1   24.87  ? 210 ASP C OD1 1 
ATOM   6181 O  OD2 . ASP C 1 214 ? -54.443 25.098  48.467  1   24.68  ? 210 ASP C OD2 1 
ATOM   6182 N  N   . GLN C 1 215 ? -56.017 21.437  47.363  1   26.28  ? 211 GLN C N   1 
ATOM   6183 C  CA  . GLN C 1 215 ? -56.017 21.076  45.952  1   26.91  ? 211 GLN C CA  1 
ATOM   6184 C  C   . GLN C 1 215 ? -57.437 20.761  45.476  1   25.91  ? 211 GLN C C   1 
ATOM   6185 O  O   . GLN C 1 215 ? -57.876 21.273  44.45   1   24.23  ? 211 GLN C O   1 
ATOM   6186 C  CB  . GLN C 1 215 ? -55.079 19.876  45.716  1   29.58  ? 211 GLN C CB  1 
ATOM   6187 C  CG  . GLN C 1 215 ? -54.796 19.537  44.263  1   31.32  ? 211 GLN C CG  1 
ATOM   6188 C  CD  . GLN C 1 215 ? -54.083 20.662  43.548  1   31.76  ? 211 GLN C CD  1 
ATOM   6189 O  OE1 . GLN C 1 215 ? -53.244 21.363  44.117  1   29.46  ? 211 GLN C OE1 1 
ATOM   6190 N  NE2 . GLN C 1 215 ? -54.423 20.872  42.289  1   33.24  ? 211 GLN C NE2 1 
ATOM   6191 N  N   . LEU C 1 216 ? -58.158 19.925  46.236  1   28.86  ? 212 LEU C N   1 
ATOM   6192 C  CA  . LEU C 1 216 ? -59.533 19.583  45.897  1   29.69  ? 212 LEU C CA  1 
ATOM   6193 C  C   . LEU C 1 216 ? -60.424 20.819  45.82   1   29.22  ? 212 LEU C C   1 
ATOM   6194 O  O   . LEU C 1 216 ? -61.156 20.999  44.843  1   29.32  ? 212 LEU C O   1 
ATOM   6195 C  CB  . LEU C 1 216 ? -60.155 18.634  46.923  1   30.5   ? 212 LEU C CB  1 
ATOM   6196 C  CG  . LEU C 1 216 ? -59.944 17.155  46.695  1   33.08  ? 212 LEU C CG  1 
ATOM   6197 C  CD1 . LEU C 1 216 ? -60.62  16.367  47.792  1   33.93  ? 212 LEU C CD1 1 
ATOM   6198 C  CD2 . LEU C 1 216 ? -60.452 16.707  45.296  1   33.75  ? 212 LEU C CD2 1 
ATOM   6199 N  N   . PHE C 1 217 ? -60.364 21.639  46.88   1   27.89  ? 213 PHE C N   1 
ATOM   6200 C  CA  . PHE C 1 217 ? -61.202 22.822  46.986  1   27.65  ? 213 PHE C CA  1 
ATOM   6201 C  C   . PHE C 1 217 ? -60.956 23.772  45.812  1   28.97  ? 213 PHE C C   1 
ATOM   6202 O  O   . PHE C 1 217 ? -61.904 24.365  45.292  1   29.53  ? 213 PHE C O   1 
ATOM   6203 C  CB  . PHE C 1 217 ? -60.988 23.551  48.339  1   26.65  ? 213 PHE C CB  1 
ATOM   6204 C  CG  . PHE C 1 217 ? -61.577 22.907  49.581  1   25.56  ? 213 PHE C CG  1 
ATOM   6205 C  CD1 . PHE C 1 217 ? -62.324 21.745  49.499  1   25.88  ? 213 PHE C CD1 1 
ATOM   6206 C  CD2 . PHE C 1 217 ? -61.373 23.464  50.83   1   25.35  ? 213 PHE C CD2 1 
ATOM   6207 C  CE1 . PHE C 1 217 ? -62.861 21.164  50.644  1   25.07  ? 213 PHE C CE1 1 
ATOM   6208 C  CE2 . PHE C 1 217 ? -61.904 22.876  51.971  1   25.86  ? 213 PHE C CE2 1 
ATOM   6209 C  CZ  . PHE C 1 217 ? -62.648 21.735  51.871  1   25.73  ? 213 PHE C CZ  1 
ATOM   6210 N  N   . ARG C 1 218 ? -59.69  23.889  45.378  1   27.14  ? 214 ARG C N   1 
ATOM   6211 C  CA  . ARG C 1 218 ? -59.361 24.751  44.255  1   27.62  ? 214 ARG C CA  1 
ATOM   6212 C  C   . ARG C 1 218 ? -59.989 24.273  42.951  1   24.84  ? 214 ARG C C   1 
ATOM   6213 O  O   . ARG C 1 218 ? -60.475 25.086  42.166  1   23.44  ? 214 ARG C O   1 
ATOM   6214 C  CB  . ARG C 1 218 ? -57.849 24.88   44.068  1   29.6   ? 214 ARG C CB  1 
ATOM   6215 C  CG  . ARG C 1 218 ? -57.243 25.827  45.056  1   32.54  ? 214 ARG C CG  1 
ATOM   6216 C  CD  . ARG C 1 218 ? -55.775 25.971  44.852  1   33.18  ? 214 ARG C CD  1 
ATOM   6217 N  NE  . ARG C 1 218 ? -55.189 26.65   45.991  1   35.39  ? 214 ARG C NE  1 
ATOM   6218 C  CZ  . ARG C 1 218 ? -54.794 27.909  45.996  1   36.48  ? 214 ARG C CZ  1 
ATOM   6219 N  NH1 . ARG C 1 218 ? -54.922 28.677  44.929  1   38.27  ? 214 ARG C NH1 1 
ATOM   6220 N  NH2 . ARG C 1 218 ? -54.272 28.414  47.108  1   36.49  ? 214 ARG C NH2 1 
ATOM   6221 N  N   . ILE C 1 219 ? -59.949 22.957  42.731  1   24.5   ? 215 ILE C N   1 
ATOM   6222 C  CA  . ILE C 1 219 ? -60.583 22.361  41.571  1   26.57  ? 215 ILE C CA  1 
ATOM   6223 C  C   . ILE C 1 219 ? -62.085 22.653  41.566  1   28.86  ? 215 ILE C C   1 
ATOM   6224 O  O   . ILE C 1 219 ? -62.627 23.127  40.561  1   28.08  ? 215 ILE C O   1 
ATOM   6225 C  CB  . ILE C 1 219 ? -60.253 20.852  41.502  1   26.03  ? 215 ILE C CB  1 
ATOM   6226 C  CG1 . ILE C 1 219 ? -58.726 20.633  41.298  1   23.91  ? 215 ILE C CG1 1 
ATOM   6227 C  CG2 . ILE C 1 219 ? -61.058 20.17   40.399  1   25.01  ? 215 ILE C CG2 1 
ATOM   6228 C  CD1 . ILE C 1 219 ? -58.234 19.203  41.544  1   22.69  ? 215 ILE C CD1 1 
ATOM   6229 N  N   . PHE C 1 220 ? -62.729 22.403  42.717  1   28.24  ? 216 PHE C N   1 
ATOM   6230 C  CA  . PHE C 1 220 ? -64.168 22.57   42.866  1   27.58  ? 216 PHE C CA  1 
ATOM   6231 C  C   . PHE C 1 220 ? -64.635 24.002  42.639  1   29.45  ? 216 PHE C C   1 
ATOM   6232 O  O   . PHE C 1 220 ? -65.637 24.227  41.961  1   30.88  ? 216 PHE C O   1 
ATOM   6233 C  CB  . PHE C 1 220 ? -64.619 22.134  44.274  1   27.21  ? 216 PHE C CB  1 
ATOM   6234 C  CG  . PHE C 1 220 ? -64.487 20.656  44.601  1   26.94  ? 216 PHE C CG  1 
ATOM   6235 C  CD1 . PHE C 1 220 ? -64.049 19.744  43.646  1   26.14  ? 216 PHE C CD1 1 
ATOM   6236 C  CD2 . PHE C 1 220 ? -64.803 20.179  45.857  1   27.59  ? 216 PHE C CD2 1 
ATOM   6237 C  CE1 . PHE C 1 220 ? -63.934 18.403  43.95   1   26.44  ? 216 PHE C CE1 1 
ATOM   6238 C  CE2 . PHE C 1 220 ? -64.671 18.837  46.155  1   27.84  ? 216 PHE C CE2 1 
ATOM   6239 C  CZ  . PHE C 1 220 ? -64.259 17.954  45.196  1   27.42  ? 216 PHE C CZ  1 
ATOM   6240 N  N   A ARG C 1 221 ? -63.888 24.964  43.197  0.5 32.09  ? 217 ARG C N   1 
ATOM   6241 N  N   B ARG C 1 221 ? -63.923 24.959  43.254  0.5 29.92  ? 217 ARG C N   1 
ATOM   6242 C  CA  A ARG C 1 221 ? -64.271 26.361  43.09   0.5 32.64  ? 217 ARG C CA  1 
ATOM   6243 C  CA  B ARG C 1 221 ? -64.219 26.378  43.12   0.5 28.93  ? 217 ARG C CA  1 
ATOM   6244 C  C   A ARG C 1 221 ? -64.132 26.865  41.654  0.5 33.43  ? 217 ARG C C   1 
ATOM   6245 C  C   B ARG C 1 221 ? -64.232 26.766  41.639  0.5 31.08  ? 217 ARG C C   1 
ATOM   6246 O  O   A ARG C 1 221 ? -64.778 27.837  41.274  0.5 32.83  ? 217 ARG C O   1 
ATOM   6247 O  O   B ARG C 1 221 ? -65.077 27.552  41.215  0.5 30.49  ? 217 ARG C O   1 
ATOM   6248 C  CB  A ARG C 1 221 ? -63.493 27.235  44.093  0.5 32.45  ? 217 ARG C CB  1 
ATOM   6249 C  CB  B ARG C 1 221 ? -63.209 27.253  43.964  0.5 26.17  ? 217 ARG C CB  1 
ATOM   6250 C  CG  A ARG C 1 221 ? -62.033 27.421  43.807  0.5 32.2   ? 217 ARG C CG  1 
ATOM   6251 C  CG  B ARG C 1 221 ? -63.579 27.394  45.477  0.5 23.78  ? 217 ARG C CG  1 
ATOM   6252 C  CD  A ARG C 1 221 ? -61.425 28.472  44.717  0.5 32.8   ? 217 ARG C CD  1 
ATOM   6253 C  CD  B ARG C 1 221 ? -62.487 27.965  46.433  0.5 21.73  ? 217 ARG C CD  1 
ATOM   6254 N  NE  A ARG C 1 221 ? -60.597 29.377  43.932  0.5 33.05  ? 217 ARG C NE  1 
ATOM   6255 N  NE  B ARG C 1 221 ? -62.828 27.672  47.825  0.5 19.24  ? 217 ARG C NE  1 
ATOM   6256 C  CZ  A ARG C 1 221 ? -59.391 29.084  43.473  0.5 32.64  ? 217 ARG C CZ  1 
ATOM   6257 C  CZ  B ARG C 1 221 ? -62.262 28.204  48.903  0.5 18.28  ? 217 ARG C CZ  1 
ATOM   6258 N  NH1 A ARG C 1 221 ? -58.3   29.468  44.111  0.5 32.07  ? 217 ARG C NH1 1 
ATOM   6259 N  NH1 B ARG C 1 221 ? -61.072 27.814  49.324  0.5 17.49  ? 217 ARG C NH1 1 
ATOM   6260 N  NH2 A ARG C 1 221 ? -59.277 28.482  42.291  0.5 34.32  ? 217 ARG C NH2 1 
ATOM   6261 N  NH2 B ARG C 1 221 ? -62.97  29.044  49.653  0.5 17.91  ? 217 ARG C NH2 1 
ATOM   6262 N  N   . THR C 1 222 ? -63.323 26.173  40.851  1   34.36  ? 218 THR C N   1 
ATOM   6263 C  CA  . THR C 1 222 ? -63.175 26.51   39.443  1   35.65  ? 218 THR C CA  1 
ATOM   6264 C  C   . THR C 1 222 ? -64.121 25.762  38.503  1   37.73  ? 218 THR C C   1 
ATOM   6265 O  O   . THR C 1 222 ? -64.684 26.373  37.596  1   37.22  ? 218 THR C O   1 
ATOM   6266 C  CB  . THR C 1 222 ? -61.746 26.252  39.018  1   35.73  ? 218 THR C CB  1 
ATOM   6267 O  OG1 . THR C 1 222 ? -60.891 27.065  39.805  1   32.6   ? 218 THR C OG1 1 
ATOM   6268 C  CG2 . THR C 1 222 ? -61.513 26.549  37.538  1   37.5   ? 218 THR C CG2 1 
ATOM   6269 N  N   . LEU C 1 223 ? -64.276 24.45   38.719  1   37.49  ? 219 LEU C N   1 
ATOM   6270 C  CA  . LEU C 1 223 ? -65.026 23.596  37.807  1   40.54  ? 219 LEU C CA  1 
ATOM   6271 C  C   . LEU C 1 223 ? -66.417 23.239  38.323  1   43.59  ? 219 LEU C C   1 
ATOM   6272 O  O   . LEU C 1 223 ? -67.174 22.55   37.64   1   42.9   ? 219 LEU C O   1 
ATOM   6273 C  CB  . LEU C 1 223 ? -64.26  22.281  37.575  1   40.94  ? 219 LEU C CB  1 
ATOM   6274 C  CG  . LEU C 1 223 ? -62.851 22.389  36.974  1   40.35  ? 219 LEU C CG  1 
ATOM   6275 C  CD1 . LEU C 1 223 ? -62.222 21.028  36.849  1   37.8   ? 219 LEU C CD1 1 
ATOM   6276 C  CD2 . LEU C 1 223 ? -62.862 23.064  35.622  1   40.74  ? 219 LEU C CD2 1 
ATOM   6277 N  N   . GLY C 1 224 ? -66.751 23.74   39.52   1   47.42  ? 220 GLY C N   1 
ATOM   6278 C  CA  . GLY C 1 224 ? -68.013 23.428  40.171  1   43.97  ? 220 GLY C CA  1 
ATOM   6279 C  C   . GLY C 1 224 ? -67.857 22.161  41.012  1   41.56  ? 220 GLY C C   1 
ATOM   6280 O  O   . GLY C 1 224 ? -67.077 21.271  40.659  1   38.08  ? 220 GLY C O   1 
ATOM   6281 N  N   . THR C 1 225 ? -68.586 22.102  42.133  1   40.09  ? 221 THR C N   1 
ATOM   6282 C  CA  . THR C 1 225 ? -68.508 20.948  43.011  1   42.66  ? 221 THR C CA  1 
ATOM   6283 C  C   . THR C 1 225 ? -69.198 19.794  42.293  1   45.67  ? 221 THR C C   1 
ATOM   6284 O  O   . THR C 1 225 ? -70.345 19.937  41.885  1   47.46  ? 221 THR C O   1 
ATOM   6285 C  CB  . THR C 1 225 ? -69.116 21.229  44.39   1   40.28  ? 221 THR C CB  1 
ATOM   6286 O  OG1 . THR C 1 225 ? -68.425 22.333  44.995  1   37.6   ? 221 THR C OG1 1 
ATOM   6287 C  CG2 . THR C 1 225 ? -69.035 19.999  45.306  1   38.32  ? 221 THR C CG2 1 
ATOM   6288 N  N   . PRO C 1 226 ? -68.533 18.635  42.094  1   52.08  ? 222 PRO C N   1 
ATOM   6289 C  CA  . PRO C 1 226 ? -69.157 17.521  41.374  1   55.26  ? 222 PRO C CA  1 
ATOM   6290 C  C   . PRO C 1 226 ? -70.193 16.813  42.239  1   60.07  ? 222 PRO C C   1 
ATOM   6291 O  O   . PRO C 1 226 ? -70.052 16.765  43.46   1   61.55  ? 222 PRO C O   1 
ATOM   6292 C  CB  . PRO C 1 226 ? -67.981 16.606  41.046  1   56.79  ? 222 PRO C CB  1 
ATOM   6293 C  CG  . PRO C 1 226 ? -67.007 16.847  42.196  1   57.13  ? 222 PRO C CG  1 
ATOM   6294 C  CD  . PRO C 1 226 ? -67.166 18.328  42.558  1   55.1   ? 222 PRO C CD  1 
ATOM   6295 N  N   . ASP C 1 227 ? -71.235 16.288  41.585  1   65.06  ? 223 ASP C N   1 
ATOM   6296 C  CA  . ASP C 1 227 ? -72.271 15.498  42.234  1   65.21  ? 223 ASP C CA  1 
ATOM   6297 C  C   . ASP C 1 227 ? -72.495 14.258  41.371  1   62.74  ? 223 ASP C C   1 
ATOM   6298 O  O   . ASP C 1 227 ? -71.749 14.027  40.421  1   56.47  ? 223 ASP C O   1 
ATOM   6299 C  CB  . ASP C 1 227 ? -73.562 16.326  42.418  1   64.8   ? 223 ASP C CB  1 
ATOM   6300 C  CG  . ASP C 1 227 ? -74.17  16.82   41.125  1   68.86  ? 223 ASP C CG  1 
ATOM   6301 O  OD1 . ASP C 1 227 ? -73.721 16.37   40.043  1   76.77  ? 223 ASP C OD1 1 
ATOM   6302 O  OD2 . ASP C 1 227 ? -75.082 17.66   41.189  1   71.93  ? 223 ASP C OD2 1 
ATOM   6303 N  N   . GLU C 1 228 ? -73.529 13.473  41.693  1   63.21  ? 224 GLU C N   1 
ATOM   6304 C  CA  . GLU C 1 228 ? -73.781 12.221  41.001  1   62.53  ? 224 GLU C CA  1 
ATOM   6305 C  C   . GLU C 1 228 ? -74.134 12.398  39.524  1   63.66  ? 224 GLU C C   1 
ATOM   6306 O  O   . GLU C 1 228 ? -73.836 11.515  38.724  1   63.88  ? 224 GLU C O   1 
ATOM   6307 C  CB  . GLU C 1 228 ? -74.88  11.431  41.732  1   60.59  ? 224 GLU C CB  1 
ATOM   6308 C  CG  . GLU C 1 228 ? -74.388 10.791  43.019  1   58.16  ? 224 GLU C CG  1 
ATOM   6309 C  CD  . GLU C 1 228 ? -73.339 9.707   42.841  1   58.53  ? 224 GLU C CD  1 
ATOM   6310 O  OE1 . GLU C 1 228 ? -73.279 9.1     41.749  1   55.17  ? 224 GLU C OE1 1 
ATOM   6311 O  OE2 . GLU C 1 228 ? -72.55  9.487   43.788  1   58.31  ? 224 GLU C OE2 1 
ATOM   6312 N  N   . VAL C 1 229 ? -74.722 13.548  39.162  1   62.15  ? 225 VAL C N   1 
ATOM   6313 C  CA  . VAL C 1 229 ? -75.118 13.805  37.785  1   58.69  ? 225 VAL C CA  1 
ATOM   6314 C  C   . VAL C 1 229 ? -73.909 14.067  36.886  1   53.75  ? 225 VAL C C   1 
ATOM   6315 O  O   . VAL C 1 229 ? -73.869 13.577  35.764  1   47.74  ? 225 VAL C O   1 
ATOM   6316 C  CB  . VAL C 1 229 ? -76.167 14.95   37.662  1   59.21  ? 225 VAL C CB  1 
ATOM   6317 C  CG1 . VAL C 1 229 ? -77.265 14.817  38.721  1   56.42  ? 225 VAL C CG1 1 
ATOM   6318 C  CG2 . VAL C 1 229 ? -75.531 16.341  37.698  1   60.06  ? 225 VAL C CG2 1 
ATOM   6319 N  N   . VAL C 1 230 ? -72.931 14.837  37.374  1   56.57  ? 226 VAL C N   1 
ATOM   6320 C  CA  . VAL C 1 230 ? -71.724 15.113  36.607  1   61.59  ? 226 VAL C CA  1 
ATOM   6321 C  C   . VAL C 1 230 ? -70.764 13.923  36.663  1   60.17  ? 226 VAL C C   1 
ATOM   6322 O  O   . VAL C 1 230 ? -70.091 13.607  35.683  1   56.57  ? 226 VAL C O   1 
ATOM   6323 C  CB  . VAL C 1 230 ? -71.004 16.406  37.104  1   60.7   ? 226 VAL C CB  1 
ATOM   6324 C  CG1 . VAL C 1 230 ? -69.893 16.835  36.137  1   57.86  ? 226 VAL C CG1 1 
ATOM   6325 C  CG2 . VAL C 1 230 ? -71.998 17.551  37.345  1   59.45  ? 226 VAL C CG2 1 
ATOM   6326 N  N   . TRP C 1 231 ? -70.695 13.273  37.83   1   59.83  ? 227 TRP C N   1 
ATOM   6327 C  CA  . TRP C 1 231 ? -69.706 12.235  38.069  1   54.19  ? 227 TRP C CA  1 
ATOM   6328 C  C   . TRP C 1 231 ? -70.332 11.101  38.874  1   52.69  ? 227 TRP C C   1 
ATOM   6329 O  O   . TRP C 1 231 ? -70.253 11.081  40.099  1   47.61  ? 227 TRP C O   1 
ATOM   6330 C  CB  . TRP C 1 231 ? -68.473 12.822  38.777  1   52.16  ? 227 TRP C CB  1 
ATOM   6331 C  CG  . TRP C 1 231 ? -67.324 11.862  38.935  1   53.79  ? 227 TRP C CG  1 
ATOM   6332 C  CD1 . TRP C 1 231 ? -67.273 10.568  38.516  1   53.22  ? 227 TRP C CD1 1 
ATOM   6333 C  CD2 . TRP C 1 231 ? -66.056 12.132  39.553  1   54.09  ? 227 TRP C CD2 1 
ATOM   6334 N  NE1 . TRP C 1 231 ? -66.049 10.019  38.814  1   53.27  ? 227 TRP C NE1 1 
ATOM   6335 C  CE2 . TRP C 1 231 ? -65.284 10.955  39.457  1   52.98  ? 227 TRP C CE2 1 
ATOM   6336 C  CE3 . TRP C 1 231 ? -65.494 13.255  40.176  1   54.88  ? 227 TRP C CE3 1 
ATOM   6337 C  CZ2 . TRP C 1 231 ? -63.99  10.866  39.966  1   52.06  ? 227 TRP C CZ2 1 
ATOM   6338 C  CZ3 . TRP C 1 231 ? -64.21  13.166  40.678  1   55.91  ? 227 TRP C CZ3 1 
ATOM   6339 C  CH2 . TRP C 1 231 ? -63.472 11.979  40.568  1   53.64  ? 227 TRP C CH2 1 
ATOM   6340 N  N   . PRO C 1 232 ? -70.985 10.123  38.209  1   55.58  ? 228 PRO C N   1 
ATOM   6341 C  CA  . PRO C 1 232 ? -71.554 8.974   38.914  1   55.59  ? 228 PRO C CA  1 
ATOM   6342 C  C   . PRO C 1 232 ? -70.491 8.236   39.728  1   51.19  ? 228 PRO C C   1 
ATOM   6343 O  O   . PRO C 1 232 ? -69.432 7.898   39.205  1   47.64  ? 228 PRO C O   1 
ATOM   6344 C  CB  . PRO C 1 232 ? -72.147 8.109   37.789  1   56.27  ? 228 PRO C CB  1 
ATOM   6345 C  CG  . PRO C 1 232 ? -72.31  9.044   36.606  1   56.55  ? 228 PRO C CG  1 
ATOM   6346 C  CD  . PRO C 1 232 ? -71.225 10.089  36.756  1   57.89  ? 228 PRO C CD  1 
ATOM   6347 N  N   . GLY C 1 233 ? -70.785 8.017   41.016  1   50.19  ? 229 GLY C N   1 
ATOM   6348 C  CA  . GLY C 1 233 ? -69.857 7.371   41.93   1   51.34  ? 229 GLY C CA  1 
ATOM   6349 C  C   . GLY C 1 233 ? -69.085 8.314   42.855  1   52.5   ? 229 GLY C C   1 
ATOM   6350 O  O   . GLY C 1 233 ? -68.617 7.881   43.909  1   56.68  ? 229 GLY C O   1 
ATOM   6351 N  N   . VAL C 1 234 ? -68.964 9.594   42.466  1   49.91  ? 230 VAL C N   1 
ATOM   6352 C  CA  . VAL C 1 234 ? -68.149 10.552  43.196  1   50.07  ? 230 VAL C CA  1 
ATOM   6353 C  C   . VAL C 1 234 ? -68.463 10.547  44.692  1   51.44  ? 230 VAL C C   1 
ATOM   6354 O  O   . VAL C 1 234 ? -67.54  10.566  45.505  1   49.57  ? 230 VAL C O   1 
ATOM   6355 C  CB  . VAL C 1 234 ? -68.24  11.993  42.601  1   50.4   ? 230 VAL C CB  1 
ATOM   6356 C  CG1 . VAL C 1 234 ? -69.606 12.627  42.817  1   51.55  ? 230 VAL C CG1 1 
ATOM   6357 C  CG2 . VAL C 1 234 ? -67.134 12.9    43.15   1   51.02  ? 230 VAL C CG2 1 
ATOM   6358 N  N   . THR C 1 235 ? -69.754 10.496  45.062  1   51.25  ? 231 THR C N   1 
ATOM   6359 C  CA  . THR C 1 235 ? -70.135 10.595  46.463  1   53.33  ? 231 THR C CA  1 
ATOM   6360 C  C   . THR C 1 235 ? -69.794 9.358   47.296  1   55.05  ? 231 THR C C   1 
ATOM   6361 O  O   . THR C 1 235 ? -69.859 9.428   48.523  1   57.49  ? 231 THR C O   1 
ATOM   6362 C  CB  . THR C 1 235 ? -71.64  10.921  46.658  1   52.35  ? 231 THR C CB  1 
ATOM   6363 O  OG1 . THR C 1 235 ? -72.422 9.867   46.104  1   51.78  ? 231 THR C OG1 1 
ATOM   6364 C  CG2 . THR C 1 235 ? -72.046 12.261  46.052  1   51.97  ? 231 THR C CG2 1 
ATOM   6365 N  N   . SER C 1 236 ? -69.451 8.232   46.645  1   53.66  ? 232 SER C N   1 
ATOM   6366 C  CA  . SER C 1 236 ? -69.027 7.042   47.377  1   53.13  ? 232 SER C CA  1 
ATOM   6367 C  C   . SER C 1 236 ? -67.521 6.795   47.266  1   53.45  ? 232 SER C C   1 
ATOM   6368 O  O   . SER C 1 236 ? -67.042 5.69    47.519  1   52.41  ? 232 SER C O   1 
ATOM   6369 C  CB  . SER C 1 236 ? -69.842 5.802   46.977  1   49.04  ? 232 SER C CB  1 
ATOM   6370 O  OG  . SER C 1 236 ? -69.904 5.585   45.579  1   49.63  ? 232 SER C OG  1 
ATOM   6371 N  N   . MET C 1 237 ? -66.763 7.836   46.907  1   54.25  ? 233 MET C N   1 
ATOM   6372 C  CA  . MET C 1 237 ? -65.316 7.713   46.828  1   56.35  ? 233 MET C CA  1 
ATOM   6373 C  C   . MET C 1 237 ? -64.705 7.702   48.229  1   53.37  ? 233 MET C C   1 
ATOM   6374 O  O   . MET C 1 237 ? -65.189 8.407   49.114  1   47.02  ? 233 MET C O   1 
ATOM   6375 C  CB  . MET C 1 237 ? -64.698 8.848   45.999  1   61.95  ? 233 MET C CB  1 
ATOM   6376 C  CG  . MET C 1 237 ? -65.062 8.796   44.546  1   63.93  ? 233 MET C CG  1 
ATOM   6377 S  SD  . MET C 1 237 ? -64.271 10.072  43.568  1   66.82  ? 233 MET C SD  1 
ATOM   6378 C  CE  . MET C 1 237 ? -65.209 11.367  44.028  1   58.23  ? 233 MET C CE  1 
ATOM   6379 N  N   . PRO C 1 238 ? -63.608 6.938   48.453  1   55.92  ? 234 PRO C N   1 
ATOM   6380 C  CA  . PRO C 1 238 ? -63.01  6.807   49.785  1   56.45  ? 234 PRO C CA  1 
ATOM   6381 C  C   . PRO C 1 238 ? -62.831 8.126   50.542  1   55.67  ? 234 PRO C C   1 
ATOM   6382 O  O   . PRO C 1 238 ? -63.177 8.212   51.719  1   49.07  ? 234 PRO C O   1 
ATOM   6383 C  CB  . PRO C 1 238 ? -61.654 6.132   49.481  1   57.51  ? 234 PRO C CB  1 
ATOM   6384 C  CG  . PRO C 1 238 ? -61.876 5.373   48.197  1   55.39  ? 234 PRO C CG  1 
ATOM   6385 C  CD  . PRO C 1 238 ? -62.877 6.175   47.421  1   56.39  ? 234 PRO C CD  1 
ATOM   6386 N  N   . ASP C 1 239 ? -62.306 9.153   49.855  1   58.72  ? 235 ASP C N   1 
ATOM   6387 C  CA  . ASP C 1 239 ? -62.029 10.432  50.489  1   59.86  ? 235 ASP C CA  1 
ATOM   6388 C  C   . ASP C 1 239 ? -62.988 11.565  50.12   1   64.24  ? 235 ASP C C   1 
ATOM   6389 O  O   . ASP C 1 239 ? -62.694 12.734  50.375  1   64.47  ? 235 ASP C O   1 
ATOM   6390 C  CB  . ASP C 1 239 ? -60.579 10.826  50.183  1   58.28  ? 235 ASP C CB  1 
ATOM   6391 C  CG  . ASP C 1 239 ? -59.588 9.877   50.807  1   56.7   ? 235 ASP C CG  1 
ATOM   6392 O  OD1 . ASP C 1 239 ? -59.77  9.525   51.99   1   60.45  ? 235 ASP C OD1 1 
ATOM   6393 O  OD2 . ASP C 1 239 ? -58.627 9.497   50.124  1   53.89  ? 235 ASP C OD2 1 
ATOM   6394 N  N   . TYR C 1 240 ? -64.136 11.217  49.522  1   63.53  ? 236 TYR C N   1 
ATOM   6395 C  CA  . TYR C 1 240 ? -65.181 12.199  49.277  1   61.57  ? 236 TYR C CA  1 
ATOM   6396 C  C   . TYR C 1 240 ? -65.87  12.502  50.608  1   60.84  ? 236 TYR C C   1 
ATOM   6397 O  O   . TYR C 1 240 ? -66.088 11.593  51.408  1   59.82  ? 236 TYR C O   1 
ATOM   6398 C  CB  . TYR C 1 240 ? -66.178 11.704  48.2    1   63.1   ? 236 TYR C CB  1 
ATOM   6399 C  CG  . TYR C 1 240 ? -67.371 12.62   48.024  1   66.8   ? 236 TYR C CG  1 
ATOM   6400 C  CD1 . TYR C 1 240 ? -68.497 12.491  48.825  1   70.81  ? 236 TYR C CD1 1 
ATOM   6401 C  CD2 . TYR C 1 240 ? -67.364 13.631  47.068  1   67.67  ? 236 TYR C CD2 1 
ATOM   6402 C  CE1 . TYR C 1 240 ? -69.591 13.343  48.681  1   69.92  ? 236 TYR C CE1 1 
ATOM   6403 C  CE2 . TYR C 1 240 ? -68.449 14.489  46.915  1   68.89  ? 236 TYR C CE2 1 
ATOM   6404 C  CZ  . TYR C 1 240 ? -69.561 14.345  47.727  1   70.45  ? 236 TYR C CZ  1 
ATOM   6405 O  OH  . TYR C 1 240 ? -70.631 15.191  47.583  1   72.85  ? 236 TYR C OH  1 
ATOM   6406 N  N   . LYS C 1 241 ? -66.188 13.782  50.839  1   59.66  ? 237 LYS C N   1 
ATOM   6407 C  CA  . LYS C 1 241 ? -66.882 14.223  52.042  1   59.47  ? 237 LYS C CA  1 
ATOM   6408 C  C   . LYS C 1 241 ? -68.206 14.923  51.715  1   52.73  ? 237 LYS C C   1 
ATOM   6409 O  O   . LYS C 1 241 ? -68.237 15.881  50.939  1   45.69  ? 237 LYS C O   1 
ATOM   6410 C  CB  . LYS C 1 241 ? -65.986 15.161  52.874  1   62.03  ? 237 LYS C CB  1 
ATOM   6411 C  CG  . LYS C 1 241 ? -64.69  14.505  53.377  1   62.5   ? 237 LYS C CG  1 
ATOM   6412 C  CD  . LYS C 1 241 ? -63.98  15.298  54.472  1   61.84  ? 237 LYS C CD  1 
ATOM   6413 C  CE  . LYS C 1 241 ? -63.559 16.678  54.034  1   60.12  ? 237 LYS C CE  1 
ATOM   6414 N  NZ  . LYS C 1 241 ? -62.918 17.424  55.142  1   59     ? 237 LYS C NZ  1 
ATOM   6415 N  N   . PRO C 1 242 ? -69.343 14.456  52.29   1   49.51  ? 238 PRO C N   1 
ATOM   6416 C  CA  . PRO C 1 242 ? -70.638 15.116  52.094  1   50.57  ? 238 PRO C CA  1 
ATOM   6417 C  C   . PRO C 1 242 ? -70.675 16.606  52.44   1   52.25  ? 238 PRO C C   1 
ATOM   6418 O  O   . PRO C 1 242 ? -71.459 17.351  51.855  1   50.74  ? 238 PRO C O   1 
ATOM   6419 C  CB  . PRO C 1 242 ? -71.585 14.325  53.012  1   46.28  ? 238 PRO C CB  1 
ATOM   6420 C  CG  . PRO C 1 242 ? -70.925 13.01   53.22   1   46.11  ? 238 PRO C CG  1 
ATOM   6421 C  CD  . PRO C 1 242 ? -69.444 13.252  53.136  1   46.63  ? 238 PRO C CD  1 
ATOM   6422 N  N   . SER C 1 243 ? -69.827 17.032  53.39   1   56.18  ? 239 SER C N   1 
ATOM   6423 C  CA  . SER C 1 243 ? -69.766 18.423  53.824  1   57.81  ? 239 SER C CA  1 
ATOM   6424 C  C   . SER C 1 243 ? -69.113 19.407  52.846  1   57.01  ? 239 SER C C   1 
ATOM   6425 O  O   . SER C 1 243 ? -69.174 20.613  53.072  1   57.26  ? 239 SER C O   1 
ATOM   6426 C  CB  . SER C 1 243 ? -69.04  18.512  55.165  1   55.02  ? 239 SER C CB  1 
ATOM   6427 O  OG  . SER C 1 243 ? -67.674 18.164  55.008  1   55.23  ? 239 SER C OG  1 
ATOM   6428 N  N   . PHE C 1 244 ? -68.479 18.91   51.772  1   55.24  ? 240 PHE C N   1 
ATOM   6429 C  CA  . PHE C 1 244 ? -67.937 19.78   50.736  1   53.77  ? 240 PHE C CA  1 
ATOM   6430 C  C   . PHE C 1 244 ? -68.87  20.927  50.339  1   52.73  ? 240 PHE C C   1 
ATOM   6431 O  O   . PHE C 1 244 ? -70.035 20.687  50.03   1   57.34  ? 240 PHE C O   1 
ATOM   6432 C  CB  . PHE C 1 244 ? -67.639 18.971  49.464  1   53.96  ? 240 PHE C CB  1 
ATOM   6433 C  CG  . PHE C 1 244 ? -66.406 18.102  49.471  1   55.43  ? 240 PHE C CG  1 
ATOM   6434 C  CD1 . PHE C 1 244 ? -65.377 18.33   50.371  1   57.15  ? 240 PHE C CD1 1 
ATOM   6435 C  CD2 . PHE C 1 244 ? -66.288 17.032  48.596  1   58.1   ? 240 PHE C CD2 1 
ATOM   6436 C  CE1 . PHE C 1 244 ? -64.242 17.515  50.374  1   61.25  ? 240 PHE C CE1 1 
ATOM   6437 C  CE2 . PHE C 1 244 ? -65.158 16.212  48.615  1   59.41  ? 240 PHE C CE2 1 
ATOM   6438 C  CZ  . PHE C 1 244 ? -64.134 16.472  49.489  1   59.81  ? 240 PHE C CZ  1 
ATOM   6439 N  N   . PRO C 1 245 ? -68.409 22.203  50.318  1   49.21  ? 241 PRO C N   1 
ATOM   6440 C  CA  . PRO C 1 245 ? -69.211 23.307  49.788  1   49.94  ? 241 PRO C CA  1 
ATOM   6441 C  C   . PRO C 1 245 ? -69.663 23.066  48.347  1   54.89  ? 241 PRO C C   1 
ATOM   6442 O  O   . PRO C 1 245 ? -68.975 22.404  47.576  1   51.49  ? 241 PRO C O   1 
ATOM   6443 C  CB  . PRO C 1 245 ? -68.261 24.521  49.926  1   44.62  ? 241 PRO C CB  1 
ATOM   6444 C  CG  . PRO C 1 245 ? -67.352 24.153  51.037  1   43.63  ? 241 PRO C CG  1 
ATOM   6445 C  CD  . PRO C 1 245 ? -67.115 22.675  50.833  1   46.79  ? 241 PRO C CD  1 
ATOM   6446 N  N   . LYS C 1 246 ? -70.845 23.598  48.01   1   61.74  ? 242 LYS C N   1 
ATOM   6447 C  CA  . LYS C 1 246 ? -71.428 23.5    46.679  1   58.6   ? 242 LYS C CA  1 
ATOM   6448 C  C   . LYS C 1 246 ? -71.118 24.737  45.832  1   51.75  ? 242 LYS C C   1 
ATOM   6449 O  O   . LYS C 1 246 ? -71.898 25.685  45.813  1   47.7   ? 242 LYS C O   1 
ATOM   6450 C  CB  . LYS C 1 246 ? -72.97  23.35   46.813  1   57.62  ? 242 LYS C CB  1 
ATOM   6451 C  CG  . LYS C 1 246 ? -73.504 21.941  47.021  1   57.7   ? 242 LYS C CG  1 
ATOM   6452 C  CD  . LYS C 1 246 ? -72.886 21.196  48.177  1   59.17  ? 242 LYS C CD  1 
ATOM   6453 C  CE  . LYS C 1 246 ? -73.163 19.715  48.109  1   59.15  ? 242 LYS C CE  1 
ATOM   6454 N  NZ  . LYS C 1 246 ? -72.014 18.944  48.637  1   58.7   ? 242 LYS C NZ  1 
ATOM   6455 N  N   . TRP C 1 247 ? -69.976 24.724  45.137  1   48.82  ? 243 TRP C N   1 
ATOM   6456 C  CA  . TRP C 1 247 ? -69.582 25.841  44.291  1   44.06  ? 243 TRP C CA  1 
ATOM   6457 C  C   . TRP C 1 247 ? -70.176 25.694  42.893  1   42.88  ? 243 TRP C C   1 
ATOM   6458 O  O   . TRP C 1 247 ? -70.22  24.595  42.341  1   43.03  ? 243 TRP C O   1 
ATOM   6459 C  CB  . TRP C 1 247 ? -68.048 25.975  44.202  1   41.88  ? 243 TRP C CB  1 
ATOM   6460 C  CG  . TRP C 1 247 ? -67.406 26.581  45.418  1   38.25  ? 243 TRP C CG  1 
ATOM   6461 C  CD1 . TRP C 1 247 ? -67.441 27.887  45.801  1   33.5   ? 243 TRP C CD1 1 
ATOM   6462 C  CD2 . TRP C 1 247 ? -66.615 25.893  46.401  1   34.18  ? 243 TRP C CD2 1 
ATOM   6463 N  NE1 . TRP C 1 247 ? -66.733 28.054  46.963  1   33.7   ? 243 TRP C NE1 1 
ATOM   6464 C  CE2 . TRP C 1 247 ? -66.217 26.844  47.356  1   33.56  ? 243 TRP C CE2 1 
ATOM   6465 C  CE3 . TRP C 1 247 ? -66.208 24.56   46.564  1   31.82  ? 243 TRP C CE3 1 
ATOM   6466 C  CZ2 . TRP C 1 247 ? -65.429 26.508  48.462  1   34.65  ? 243 TRP C CZ2 1 
ATOM   6467 C  CZ3 . TRP C 1 247 ? -65.433 24.229  47.659  1   32.97  ? 243 TRP C CZ3 1 
ATOM   6468 C  CH2 . TRP C 1 247 ? -65.054 25.195  48.596  1   34     ? 243 TRP C CH2 1 
ATOM   6469 N  N   . ALA C 1 248 ? -70.623 26.824  42.334  1   43.61  ? 244 ALA C N   1 
ATOM   6470 C  CA  . ALA C 1 248 ? -71.037 26.882  40.944  1   46.6   ? 244 ALA C CA  1 
ATOM   6471 C  C   . ALA C 1 248 ? -69.813 26.817  40.028  1   50.08  ? 244 ALA C C   1 
ATOM   6472 O  O   . ALA C 1 248 ? -68.753 27.353  40.351  1   50     ? 244 ALA C O   1 
ATOM   6473 C  CB  . ALA C 1 248 ? -71.836 28.15   40.688  1   46.75  ? 244 ALA C CB  1 
ATOM   6474 N  N   . ARG C 1 249 ? -69.97  26.135  38.888  1   51.5   ? 245 ARG C N   1 
ATOM   6475 C  CA  . ARG C 1 249 ? -68.946 26.103  37.858  1   52.96  ? 245 ARG C CA  1 
ATOM   6476 C  C   . ARG C 1 249 ? -68.767 27.503  37.279  1   59.17  ? 245 ARG C C   1 
ATOM   6477 O  O   . ARG C 1 249 ? -69.745 28.148  36.917  1   59.07  ? 245 ARG C O   1 
ATOM   6478 C  CB  . ARG C 1 249 ? -69.341 25.129  36.741  1   49.71  ? 245 ARG C CB  1 
ATOM   6479 C  CG  . ARG C 1 249 ? -68.315 25.052  35.623  1   47.83  ? 245 ARG C CG  1 
ATOM   6480 C  CD  . ARG C 1 249 ? -68.801 24.223  34.473  1   47.48  ? 245 ARG C CD  1 
ATOM   6481 N  NE  . ARG C 1 249 ? -67.813 24.187  33.4    1   47.08  ? 245 ARG C NE  1 
ATOM   6482 C  CZ  . ARG C 1 249 ? -66.945 23.201  33.222  1   45.44  ? 245 ARG C CZ  1 
ATOM   6483 N  NH1 . ARG C 1 249 ? -66.583 22.412  34.222  1   44.38  ? 245 ARG C NH1 1 
ATOM   6484 N  NH2 . ARG C 1 249 ? -66.416 23.007  32.015  1   42.64  ? 245 ARG C NH2 1 
ATOM   6485 N  N   . GLN C 1 250 ? -67.519 27.967  37.191  1   66.73  ? 246 GLN C N   1 
ATOM   6486 C  CA  . GLN C 1 250 ? -67.247 29.275  36.623  1   69.07  ? 246 GLN C CA  1 
ATOM   6487 C  C   . GLN C 1 250 ? -67.222 29.232  35.098  1   66.92  ? 246 GLN C C   1 
ATOM   6488 O  O   . GLN C 1 250 ? -66.884 28.211  34.497  1   66.86  ? 246 GLN C O   1 
ATOM   6489 C  CB  . GLN C 1 250 ? -65.911 29.812  37.119  1   71.95  ? 246 GLN C CB  1 
ATOM   6490 C  CG  . GLN C 1 250 ? -65.855 30.16   38.595  1   72.5   ? 246 GLN C CG  1 
ATOM   6491 C  CD  . GLN C 1 250 ? -64.441 30.518  38.946  1   75.88  ? 246 GLN C CD  1 
ATOM   6492 O  OE1 . GLN C 1 250 ? -63.795 31.295  38.239  1   78.41  ? 246 GLN C OE1 1 
ATOM   6493 N  NE2 . GLN C 1 250 ? -63.906 29.933  40.01   1   77.13  ? 246 GLN C NE2 1 
ATOM   6494 N  N   . ASP C 1 251 ? -67.609 30.358  34.493  1   68.39  ? 247 ASP C N   1 
ATOM   6495 C  CA  . ASP C 1 251 ? -67.531 30.53   33.055  1   67.79  ? 247 ASP C CA  1 
ATOM   6496 C  C   . ASP C 1 251 ? -66.064 30.386  32.658  1   63.09  ? 247 ASP C C   1 
ATOM   6497 O  O   . ASP C 1 251 ? -65.197 31.046  33.223  1   55.59  ? 247 ASP C O   1 
ATOM   6498 C  CB  . ASP C 1 251 ? -68.089 31.905  32.648  1   68.97  ? 247 ASP C CB  1 
ATOM   6499 C  CG  . ASP C 1 251 ? -68.602 31.986  31.231  1   71.48  ? 247 ASP C CG  1 
ATOM   6500 O  OD1 . ASP C 1 251 ? -67.781 31.861  30.288  1   76.32  ? 247 ASP C OD1 1 
ATOM   6501 O  OD2 . ASP C 1 251 ? -69.822 32.177  31.06   1   68.13  ? 247 ASP C OD2 1 
ATOM   6502 N  N   . PHE C 1 252 ? -65.788 29.52   31.679  1   65.53  ? 248 PHE C N   1 
ATOM   6503 C  CA  . PHE C 1 252 ? -64.423 29.302  31.224  1   67.07  ? 248 PHE C CA  1 
ATOM   6504 C  C   . PHE C 1 252 ? -63.801 30.516  30.534  1   70.53  ? 248 PHE C C   1 
ATOM   6505 O  O   . PHE C 1 252 ? -62.577 30.604  30.439  1   73.59  ? 248 PHE C O   1 
ATOM   6506 C  CB  . PHE C 1 252 ? -64.371 28.075  30.307  1   64.69  ? 248 PHE C CB  1 
ATOM   6507 C  CG  . PHE C 1 252 ? -63.853 26.83   30.974  1   67.72  ? 248 PHE C CG  1 
ATOM   6508 C  CD1 . PHE C 1 252 ? -64.223 26.511  32.273  1   70.53  ? 248 PHE C CD1 1 
ATOM   6509 C  CD2 . PHE C 1 252 ? -63.003 25.972  30.302  1   63.67  ? 248 PHE C CD2 1 
ATOM   6510 C  CE1 . PHE C 1 252 ? -63.735 25.37   32.885  1   69.75  ? 248 PHE C CE1 1 
ATOM   6511 C  CE2 . PHE C 1 252 ? -62.519 24.835  30.915  1   62.79  ? 248 PHE C CE2 1 
ATOM   6512 C  CZ  . PHE C 1 252 ? -62.891 24.534  32.201  1   66.17  ? 248 PHE C CZ  1 
ATOM   6513 N  N   . SER C 1 253 ? -64.651 31.445  30.079  1   70.95  ? 249 SER C N   1 
ATOM   6514 C  CA  . SER C 1 253 ? -64.225 32.743  29.577  1   69.57  ? 249 SER C CA  1 
ATOM   6515 C  C   . SER C 1 253 ? -63.571 33.646  30.627  1   66.6   ? 249 SER C C   1 
ATOM   6516 O  O   . SER C 1 253 ? -62.89  34.601  30.259  1   58.02  ? 249 SER C O   1 
ATOM   6517 C  CB  . SER C 1 253 ? -65.413 33.486  28.963  1   68.13  ? 249 SER C CB  1 
ATOM   6518 O  OG  . SER C 1 253 ? -66.09  32.7    27.993  1   67.03  ? 249 SER C OG  1 
ATOM   6519 N  N   . LYS C 1 254 ? -63.796 33.375  31.921  1   64.78  ? 250 LYS C N   1 
ATOM   6520 C  CA  . LYS C 1 254 ? -63.051 34.093  32.948  1   60.44  ? 250 LYS C CA  1 
ATOM   6521 C  C   . LYS C 1 254 ? -61.856 33.272  33.428  1   54.14  ? 250 LYS C C   1 
ATOM   6522 O  O   . LYS C 1 254 ? -60.882 33.832  33.917  1   54.35  ? 250 LYS C O   1 
ATOM   6523 C  CB  . LYS C 1 254 ? -63.933 34.541  34.144  1   64.41  ? 250 LYS C CB  1 
ATOM   6524 C  CG  . LYS C 1 254 ? -64.556 33.421  34.969  1   66.26  ? 250 LYS C CG  1 
ATOM   6525 C  CD  . LYS C 1 254 ? -65.41  33.919  36.169  1   67.16  ? 250 LYS C CD  1 
ATOM   6526 C  CE  . LYS C 1 254 ? -66.03  32.809  36.99   1   64.61  ? 250 LYS C CE  1 
ATOM   6527 N  NZ  . LYS C 1 254 ? -66.832 33.337  38.119  1   62.74  ? 250 LYS C NZ  1 
ATOM   6528 N  N   . VAL C 1 255 ? -61.945 31.943  33.279  1   50.79  ? 251 VAL C N   1 
ATOM   6529 C  CA  . VAL C 1 255 ? -60.902 31.026  33.715  1   48.93  ? 251 VAL C CA  1 
ATOM   6530 C  C   . VAL C 1 255 ? -59.657 31.134  32.841  1   47.37  ? 251 VAL C C   1 
ATOM   6531 O  O   . VAL C 1 255 ? -58.545 31.163  33.36   1   46.71  ? 251 VAL C O   1 
ATOM   6532 C  CB  . VAL C 1 255 ? -61.426 29.577  33.713  1   50.37  ? 251 VAL C CB  1 
ATOM   6533 C  CG1 . VAL C 1 255 ? -60.303 28.568  33.968  1   48.8   ? 251 VAL C CG1 1 
ATOM   6534 C  CG2 . VAL C 1 255 ? -62.563 29.416  34.719  1   49.88  ? 251 VAL C CG2 1 
ATOM   6535 N  N   . VAL C 1 256 ? -59.86  31.166  31.518  1   45.21  ? 252 VAL C N   1 
ATOM   6536 C  CA  . VAL C 1 256 ? -58.779 31.342  30.564  1   46.86  ? 252 VAL C CA  1 
ATOM   6537 C  C   . VAL C 1 256 ? -59.205 32.374  29.52   1   46     ? 252 VAL C C   1 
ATOM   6538 O  O   . VAL C 1 256 ? -59.503 32.024  28.377  1   45.96  ? 252 VAL C O   1 
ATOM   6539 C  CB  . VAL C 1 256 ? -58.336 29.98   29.926  1   48.49  ? 252 VAL C CB  1 
ATOM   6540 C  CG1 . VAL C 1 256 ? -57.47  29.173  30.879  1   47.1   ? 252 VAL C CG1 1 
ATOM   6541 C  CG2 . VAL C 1 256 ? -59.527 29.14   29.45   1   49.09  ? 252 VAL C CG2 1 
ATOM   6542 N  N   . PRO C 1 257 ? -59.22  33.681  29.876  1   47.48  ? 253 PRO C N   1 
ATOM   6543 C  CA  . PRO C 1 257 ? -59.727 34.729  28.982  1   45.28  ? 253 PRO C CA  1 
ATOM   6544 C  C   . PRO C 1 257 ? -59.223 34.725  27.535  1   45.92  ? 253 PRO C C   1 
ATOM   6545 O  O   . PRO C 1 257 ? -60.027 34.898  26.62   1   46.15  ? 253 PRO C O   1 
ATOM   6546 C  CB  . PRO C 1 257 ? -59.311 36.027  29.695  1   46.13  ? 253 PRO C CB  1 
ATOM   6547 C  CG  . PRO C 1 257 ? -59.201 35.65   31.157  1   47.8   ? 253 PRO C CG  1 
ATOM   6548 C  CD  . PRO C 1 257 ? -58.75  34.213  31.171  1   48.54  ? 253 PRO C CD  1 
ATOM   6549 N  N   . PRO C 1 258 ? -57.91  34.531  27.25   1   45.86  ? 254 PRO C N   1 
ATOM   6550 C  CA  . PRO C 1 258 ? -57.425 34.602  25.867  1   44.68  ? 254 PRO C CA  1 
ATOM   6551 C  C   . PRO C 1 258 ? -57.911 33.485  24.947  1   44     ? 254 PRO C C   1 
ATOM   6552 O  O   . PRO C 1 258 ? -57.754 33.577  23.73   1   41.15  ? 254 PRO C O   1 
ATOM   6553 C  CB  . PRO C 1 258 ? -55.893 34.526  26.013  1   43.83  ? 254 PRO C CB  1 
ATOM   6554 C  CG  . PRO C 1 258 ? -55.608 34.707  27.494  1   43.17  ? 254 PRO C CG  1 
ATOM   6555 C  CD  . PRO C 1 258 ? -56.83  34.244  28.214  1   43.35  ? 254 PRO C CD  1 
ATOM   6556 N  N   . LEU C 1 259 ? -58.503 32.442  25.542  1   44.85  ? 255 LEU C N   1 
ATOM   6557 C  CA  . LEU C 1 259 ? -58.786 31.203  24.843  1   46.89  ? 255 LEU C CA  1 
ATOM   6558 C  C   . LEU C 1 259 ? -60.11  31.285  24.09   1   48.09  ? 255 LEU C C   1 
ATOM   6559 O  O   . LEU C 1 259 ? -61.11  31.751  24.635  1   53.09  ? 255 LEU C O   1 
ATOM   6560 C  CB  . LEU C 1 259 ? -58.809 30.081  25.88   1   48.48  ? 255 LEU C CB  1 
ATOM   6561 C  CG  . LEU C 1 259 ? -58.53  28.683  25.387  1   46.89  ? 255 LEU C CG  1 
ATOM   6562 C  CD1 . LEU C 1 259 ? -57.21  28.623  24.631  1   45.69  ? 255 LEU C CD1 1 
ATOM   6563 C  CD2 . LEU C 1 259 ? -58.537 27.709  26.558  1   45.51  ? 255 LEU C CD2 1 
ATOM   6564 N  N   . ASP C 1 260 ? -60.096 30.821  22.834  1   47.41  ? 256 ASP C N   1 
ATOM   6565 C  CA  . ASP C 1 260 ? -61.263 30.854  21.965  1   48.99  ? 256 ASP C CA  1 
ATOM   6566 C  C   . ASP C 1 260 ? -62.245 29.731  22.307  1   46.97  ? 256 ASP C C   1 
ATOM   6567 O  O   . ASP C 1 260 ? -61.986 28.903  23.178  1   48.63  ? 256 ASP C O   1 
ATOM   6568 C  CB  . ASP C 1 260 ? -60.825 30.783  20.476  1   50.23  ? 256 ASP C CB  1 
ATOM   6569 C  CG  . ASP C 1 260 ? -60.019 29.549  20.078  1   50.47  ? 256 ASP C CG  1 
ATOM   6570 O  OD1 . ASP C 1 260 ? -58.905 29.379  20.595  1   50.77  ? 256 ASP C OD1 1 
ATOM   6571 O  OD2 . ASP C 1 260 ? -60.501 28.772  19.233  1   51.44  ? 256 ASP C OD2 1 
ATOM   6572 N  N   . GLU C 1 261 ? -63.386 29.709  21.612  1   45.19  ? 257 GLU C N   1 
ATOM   6573 C  CA  . GLU C 1 261 ? -64.432 28.734  21.88   1   44.02  ? 257 GLU C CA  1 
ATOM   6574 C  C   . GLU C 1 261 ? -63.955 27.288  21.72   1   40.84  ? 257 GLU C C   1 
ATOM   6575 O  O   . GLU C 1 261 ? -64.312 26.428  22.522  1   36.97  ? 257 GLU C O   1 
ATOM   6576 C  CB  . GLU C 1 261 ? -65.615 29.016  20.953  1   44.48  ? 257 GLU C CB  1 
ATOM   6577 C  CG  . GLU C 1 261 ? -66.835 28.168  21.233  1   48.63  ? 257 GLU C CG  1 
ATOM   6578 C  CD  . GLU C 1 261 ? -67.946 28.328  20.214  1   53.22  ? 257 GLU C CD  1 
ATOM   6579 O  OE1 . GLU C 1 261 ? -67.808 29.17   19.296  1   55.35  ? 257 GLU C OE1 1 
ATOM   6580 O  OE2 . GLU C 1 261 ? -68.956 27.598  20.328  1   54.68  ? 257 GLU C OE2 1 
ATOM   6581 N  N   . ASP C 1 262 ? -63.155 27.027  20.678  1   38.57  ? 258 ASP C N   1 
ATOM   6582 C  CA  . ASP C 1 262 ? -62.601 25.704  20.436  1   38.17  ? 258 ASP C CA  1 
ATOM   6583 C  C   . ASP C 1 262 ? -61.642 25.281  21.548  1   37.33  ? 258 ASP C C   1 
ATOM   6584 O  O   . ASP C 1 262 ? -61.702 24.149  22.022  1   36.51  ? 258 ASP C O   1 
ATOM   6585 C  CB  . ASP C 1 262 ? -61.867 25.652  19.077  1   37.77  ? 258 ASP C CB  1 
ATOM   6586 C  CG  . ASP C 1 262 ? -62.751 25.573  17.846  1   37.97  ? 258 ASP C CG  1 
ATOM   6587 O  OD1 . ASP C 1 262 ? -63.94  25.222  17.99   1   37.46  ? 258 ASP C OD1 1 
ATOM   6588 O  OD2 . ASP C 1 262 ? -62.249 25.864  16.741  1   35.54  ? 258 ASP C OD2 1 
ATOM   6589 N  N   . GLY C 1 263 ? -60.75  26.192  21.949  1   34.6   ? 259 GLY C N   1 
ATOM   6590 C  CA  . GLY C 1 263 ? -59.837 25.914  23.042  1   33.03  ? 259 GLY C CA  1 
ATOM   6591 C  C   . GLY C 1 263 ? -60.572 25.594  24.343  1   32.21  ? 259 GLY C C   1 
ATOM   6592 O  O   . GLY C 1 263 ? -60.223 24.643  25.032  1   30.91  ? 259 GLY C O   1 
ATOM   6593 N  N   . ARG C 1 264 ? -61.591 26.396  24.665  1   32.3   ? 260 ARG C N   1 
ATOM   6594 C  CA  . ARG C 1 264 ? -62.372 26.201  25.879  1   32.22  ? 260 ARG C CA  1 
ATOM   6595 C  C   . ARG C 1 264 ? -63.064 24.838  25.864  1   29.33  ? 260 ARG C C   1 
ATOM   6596 O  O   . ARG C 1 264 ? -63.095 24.125  26.863  1   31.33  ? 260 ARG C O   1 
ATOM   6597 C  CB  . ARG C 1 264 ? -63.409 27.324  26.048  1   34.36  ? 260 ARG C CB  1 
ATOM   6598 C  CG  . ARG C 1 264 ? -62.779 28.716  26.3    1   37.32  ? 260 ARG C CG  1 
ATOM   6599 C  CD  . ARG C 1 264 ? -63.753 29.739  26.844  1   37.14  ? 260 ARG C CD  1 
ATOM   6600 N  NE  . ARG C 1 264 ? -64.92  29.893  25.986  1   39.2   ? 260 ARG C NE  1 
ATOM   6601 C  CZ  . ARG C 1 264 ? -65.029 30.797  25.022  1   40.77  ? 260 ARG C CZ  1 
ATOM   6602 N  NH1 . ARG C 1 264 ? -64.031 31.612  24.72   1   42.92  ? 260 ARG C NH1 1 
ATOM   6603 N  NH2 . ARG C 1 264 ? -66.148 30.851  24.303  1   38.61  ? 260 ARG C NH2 1 
ATOM   6604 N  N   . SER C 1 265 ? -63.621 24.491  24.706  1   28.16  ? 261 SER C N   1 
ATOM   6605 C  CA  . SER C 1 265 ? -64.267 23.209  24.502  1   27.01  ? 261 SER C CA  1 
ATOM   6606 C  C   . SER C 1 265 ? -63.305 22.058  24.796  1   27.05  ? 261 SER C C   1 
ATOM   6607 O  O   . SER C 1 265 ? -63.614 21.16   25.576  1   27.37  ? 261 SER C O   1 
ATOM   6608 C  CB  . SER C 1 265 ? -64.802 23.141  23.071  1   26.87  ? 261 SER C CB  1 
ATOM   6609 O  OG  . SER C 1 265 ? -65.223 21.838  22.72   1   27.39  ? 261 SER C OG  1 
ATOM   6610 N  N   . LEU C 1 266 ? -62.125 22.096  24.178  1   26.52  ? 262 LEU C N   1 
ATOM   6611 C  CA  . LEU C 1 266 ? -61.141 21.047  24.385  1   28.45  ? 262 LEU C CA  1 
ATOM   6612 C  C   . LEU C 1 266 ? -60.664 21.024  25.841  1   29.37  ? 262 LEU C C   1 
ATOM   6613 O  O   . LEU C 1 266 ? -60.558 19.958  26.45   1   28.97  ? 262 LEU C O   1 
ATOM   6614 C  CB  . LEU C 1 266 ? -59.959 21.225  23.401  1   28.37  ? 262 LEU C CB  1 
ATOM   6615 C  CG  . LEU C 1 266 ? -58.719 20.365  23.679  1   27.69  ? 262 LEU C CG  1 
ATOM   6616 C  CD1 . LEU C 1 266 ? -59.038 18.905  23.548  1   28.05  ? 262 LEU C CD1 1 
ATOM   6617 C  CD2 . LEU C 1 266 ? -57.589 20.754  22.783  1   27.65  ? 262 LEU C CD2 1 
ATOM   6618 N  N   . LEU C 1 267 ? -60.386 22.2    26.412  1   27.87  ? 263 LEU C N   1 
ATOM   6619 C  CA  . LEU C 1 267 ? -59.937 22.268  27.793  1   28.46  ? 263 LEU C CA  1 
ATOM   6620 C  C   . LEU C 1 267 ? -60.948 21.623  28.745  1   28.4   ? 263 LEU C C   1 
ATOM   6621 O  O   . LEU C 1 267 ? -60.558 20.842  29.609  1   28.54  ? 263 LEU C O   1 
ATOM   6622 C  CB  . LEU C 1 267 ? -59.658 23.717  28.214  1   26.31  ? 263 LEU C CB  1 
ATOM   6623 C  CG  . LEU C 1 267 ? -59.186 23.905  29.649  1   27.22  ? 263 LEU C CG  1 
ATOM   6624 C  CD1 . LEU C 1 267 ? -57.91  23.112  29.947  1   27.83  ? 263 LEU C CD1 1 
ATOM   6625 C  CD2 . LEU C 1 267 ? -58.964 25.402  29.934  1   27.7   ? 263 LEU C CD2 1 
ATOM   6626 N  N   . SER C 1 268 ? -62.24  21.935  28.579  1   26.9   ? 264 SER C N   1 
ATOM   6627 C  CA  . SER C 1 268 ? -63.264 21.361  29.439  1   26.88  ? 264 SER C CA  1 
ATOM   6628 C  C   . SER C 1 268 ? -63.333 19.839  29.315  1   26.26  ? 264 SER C C   1 
ATOM   6629 O  O   . SER C 1 268 ? -63.491 19.15   30.312  1   25.11  ? 264 SER C O   1 
ATOM   6630 C  CB  . SER C 1 268 ? -64.626 22.004  29.184  1   27.57  ? 264 SER C CB  1 
ATOM   6631 O  OG  . SER C 1 268 ? -65.06  21.794  27.854  1   32.08  ? 264 SER C OG  1 
ATOM   6632 N  N   . GLN C 1 269 ? -63.152 19.312  28.102  1   27.03  ? 265 GLN C N   1 
ATOM   6633 C  CA  . GLN C 1 269 ? -63.147 17.871  27.896  1   28.36  ? 265 GLN C CA  1 
ATOM   6634 C  C   . GLN C 1 269 ? -61.934 17.177  28.521  1   30.38  ? 265 GLN C C   1 
ATOM   6635 O  O   . GLN C 1 269 ? -62.009 16.008  28.908  1   31.17  ? 265 GLN C O   1 
ATOM   6636 C  CB  . GLN C 1 269 ? -63.23  17.564  26.397  1   28.09  ? 265 GLN C CB  1 
ATOM   6637 C  CG  . GLN C 1 269 ? -64.579 17.947  25.81   1   28.12  ? 265 GLN C CG  1 
ATOM   6638 C  CD  . GLN C 1 269 ? -64.636 17.718  24.312  1   29.15  ? 265 GLN C CD  1 
ATOM   6639 O  OE1 . GLN C 1 269 ? -64.526 16.594  23.819  1   30.91  ? 265 GLN C OE1 1 
ATOM   6640 N  NE2 . GLN C 1 269 ? -64.821 18.774  23.549  1   27.71  ? 265 GLN C NE2 1 
ATOM   6641 N  N   . MET C 1 270 ? -60.819 17.909  28.629  1   29.2   ? 266 MET C N   1 
ATOM   6642 C  CA  . MET C 1 270 ? -59.631 17.38   29.276  1   30.05  ? 266 MET C CA  1 
ATOM   6643 C  C   . MET C 1 270 ? -59.771 17.391  30.794  1   28.84  ? 266 MET C C   1 
ATOM   6644 O  O   . MET C 1 270 ? -59.172 16.558  31.472  1   26.79  ? 266 MET C O   1 
ATOM   6645 C  CB  . MET C 1 270 ? -58.393 18.18   28.834  1   29.62  ? 266 MET C CB  1 
ATOM   6646 C  CG  . MET C 1 270 ? -58.053 17.922  27.397  1   29.62  ? 266 MET C CG  1 
ATOM   6647 S  SD  . MET C 1 270 ? -56.722 18.933  26.789  1   30.25  ? 266 MET C SD  1 
ATOM   6648 C  CE  . MET C 1 270 ? -55.285 17.931  27.301  1   28.7   ? 266 MET C CE  1 
ATOM   6649 N  N   . LEU C 1 271 ? -60.577 18.33   31.31   1   30.5   ? 267 LEU C N   1 
ATOM   6650 C  CA  . LEU C 1 271 ? -60.749 18.5    32.744  1   31.7   ? 267 LEU C CA  1 
ATOM   6651 C  C   . LEU C 1 271 ? -62.097 17.983  33.241  1   31.35  ? 267 LEU C C   1 
ATOM   6652 O  O   . LEU C 1 271 ? -62.589 18.409  34.278  1   29.64  ? 267 LEU C O   1 
ATOM   6653 C  CB  . LEU C 1 271 ? -60.585 19.997  33.076  1   32.87  ? 267 LEU C CB  1 
ATOM   6654 C  CG  . LEU C 1 271 ? -59.208 20.583  32.779  1   32     ? 267 LEU C CG  1 
ATOM   6655 C  CD1 . LEU C 1 271 ? -59.162 22.062  33.121  1   32.76  ? 267 LEU C CD1 1 
ATOM   6656 C  CD2 . LEU C 1 271 ? -58.123 19.829  33.541  1   32.16  ? 267 LEU C CD2 1 
ATOM   6657 N  N   . HIS C 1 272 ? -62.678 17.028  32.511  1   35.61  ? 268 HIS C N   1 
ATOM   6658 C  CA  . HIS C 1 272 ? -63.919 16.406  32.935  1   35.24  ? 268 HIS C CA  1 
ATOM   6659 C  C   . HIS C 1 272 ? -63.649 15.636  34.225  1   33.39  ? 268 HIS C C   1 
ATOM   6660 O  O   . HIS C 1 272 ? -62.627 14.958  34.352  1   31.42  ? 268 HIS C O   1 
ATOM   6661 C  CB  . HIS C 1 272 ? -64.463 15.49   31.829  1   39     ? 268 HIS C CB  1 
ATOM   6662 C  CG  . HIS C 1 272 ? -65.937 15.233  31.905  1   41.95  ? 268 HIS C CG  1 
ATOM   6663 N  ND1 . HIS C 1 272 ? -66.512 14.631  33.012  1   43.16  ? 268 HIS C ND1 1 
ATOM   6664 C  CD2 . HIS C 1 272 ? -66.907 15.524  31.009  1   44.06  ? 268 HIS C CD2 1 
ATOM   6665 C  CE1 . HIS C 1 272 ? -67.811 14.57   32.759  1   44.35  ? 268 HIS C CE1 1 
ATOM   6666 N  NE2 . HIS C 1 272 ? -68.094 15.099  31.559  1   46.49  ? 268 HIS C NE2 1 
ATOM   6667 N  N   . TYR C 1 273 ? -64.569 15.763  35.185  1   32.24  ? 269 TYR C N   1 
ATOM   6668 C  CA  . TYR C 1 273 ? -64.443 15.104  36.475  1   32.22  ? 269 TYR C CA  1 
ATOM   6669 C  C   . TYR C 1 273 ? -64.377 13.59   36.293  1   29.85  ? 269 TYR C C   1 
ATOM   6670 O  O   . TYR C 1 273 ? -63.468 12.939  36.799  1   29.99  ? 269 TYR C O   1 
ATOM   6671 C  CB  . TYR C 1 273 ? -65.614 15.496  37.401  1   33.08  ? 269 TYR C CB  1 
ATOM   6672 C  CG  . TYR C 1 273 ? -65.372 16.771  38.173  1   35.87  ? 269 TYR C CG  1 
ATOM   6673 C  CD1 . TYR C 1 273 ? -64.419 16.826  39.178  1   36.86  ? 269 TYR C CD1 1 
ATOM   6674 C  CD2 . TYR C 1 273 ? -66.084 17.934  37.883  1   38.1   ? 269 TYR C CD2 1 
ATOM   6675 C  CE1 . TYR C 1 273 ? -64.179 18.005  39.882  1   38.22  ? 269 TYR C CE1 1 
ATOM   6676 C  CE2 . TYR C 1 273 ? -65.847 19.125  38.576  1   36.59  ? 269 TYR C CE2 1 
ATOM   6677 C  CZ  . TYR C 1 273 ? -64.898 19.154  39.58   1   36.99  ? 269 TYR C CZ  1 
ATOM   6678 O  OH  . TYR C 1 273 ? -64.654 20.319  40.271  1   38.88  ? 269 TYR C OH  1 
ATOM   6679 N  N   . ASP C 1 274 ? -65.354 13.048  35.56   1   29.55  ? 270 ASP C N   1 
ATOM   6680 C  CA  . ASP C 1 274 ? -65.493 11.615  35.385  1   28.55  ? 270 ASP C CA  1 
ATOM   6681 C  C   . ASP C 1 274 ? -64.351 11.118  34.509  1   30.82  ? 270 ASP C C   1 
ATOM   6682 O  O   . ASP C 1 274 ? -64.254 11.506  33.35   1   30.21  ? 270 ASP C O   1 
ATOM   6683 C  CB  . ASP C 1 274 ? -66.862 11.277  34.773  1   27.13  ? 270 ASP C CB  1 
ATOM   6684 C  CG  . ASP C 1 274 ? -67.201 9.8     34.72   1   26.41  ? 270 ASP C CG  1 
ATOM   6685 O  OD1 . ASP C 1 274 ? -66.27  8.963   34.846  1   23.67  ? 270 ASP C OD1 1 
ATOM   6686 O  OD2 . ASP C 1 274 ? -68.4   9.477   34.578  1   29.27  ? 270 ASP C OD2 1 
ATOM   6687 N  N   . PRO C 1 275 ? -63.455 10.246  35.027  1   34.63  ? 271 PRO C N   1 
ATOM   6688 C  CA  . PRO C 1 275 ? -62.35  9.716   34.224  1   34.87  ? 271 PRO C CA  1 
ATOM   6689 C  C   . PRO C 1 275 ? -62.836 9.017   32.957  1   33.91  ? 271 PRO C C   1 
ATOM   6690 O  O   . PRO C 1 275 ? -62.151 9.038   31.935  1   33.9   ? 271 PRO C O   1 
ATOM   6691 C  CB  . PRO C 1 275 ? -61.653 8.748   35.187  1   34.93  ? 271 PRO C CB  1 
ATOM   6692 C  CG  . PRO C 1 275 ? -62.065 9.205   36.547  1   35.34  ? 271 PRO C CG  1 
ATOM   6693 C  CD  . PRO C 1 275 ? -63.458 9.71    36.397  1   34.2   ? 271 PRO C CD  1 
ATOM   6694 N  N   . ASN C 1 276 ? -64.037 8.424   33.031  1   33.1   ? 272 ASN C N   1 
ATOM   6695 C  CA  . ASN C 1 276 ? -64.615 7.703   31.91   1   34.7   ? 272 ASN C CA  1 
ATOM   6696 C  C   . ASN C 1 276 ? -65.087 8.602   30.772  1   33.47  ? 272 ASN C C   1 
ATOM   6697 O  O   . ASN C 1 276 ? -65.134 8.148   29.633  1   29.63  ? 272 ASN C O   1 
ATOM   6698 C  CB  . ASN C 1 276 ? -65.783 6.83    32.358  1   36.99  ? 272 ASN C CB  1 
ATOM   6699 C  CG  . ASN C 1 276 ? -65.377 5.743   33.334  1   39.22  ? 272 ASN C CG  1 
ATOM   6700 O  OD1 . ASN C 1 276 ? -64.352 5.058   33.158  1   38.21  ? 272 ASN C OD1 1 
ATOM   6701 N  ND2 . ASN C 1 276 ? -66.165 5.557   34.394  1   41.38  ? 272 ASN C ND2 1 
ATOM   6702 N  N   . LYS C 1 277 ? -65.447 9.854   31.09   1   34.17  ? 273 LYS C N   1 
ATOM   6703 C  CA  . LYS C 1 277 ? -65.913 10.804  30.093  1   35.6   ? 273 LYS C CA  1 
ATOM   6704 C  C   . LYS C 1 277 ? -64.798 11.708  29.585  1   32.02  ? 273 LYS C C   1 
ATOM   6705 O  O   . LYS C 1 277 ? -64.949 12.321  28.535  1   31.16  ? 273 LYS C O   1 
ATOM   6706 C  CB  . LYS C 1 277 ? -67.032 11.685  30.653  1   42.22  ? 273 LYS C CB  1 
ATOM   6707 C  CG  . LYS C 1 277 ? -68.307 10.916  31      1   51.28  ? 273 LYS C CG  1 
ATOM   6708 C  CD  . LYS C 1 277 ? -69.498 11.831  31.313  1   57.06  ? 273 LYS C CD  1 
ATOM   6709 C  CE  . LYS C 1 277 ? -70.564 11.167  32.159  1   57.87  ? 273 LYS C CE  1 
ATOM   6710 N  NZ  . LYS C 1 277 ? -71.282 12.172  32.98   1   58.77  ? 273 LYS C NZ  1 
ATOM   6711 N  N   . ARG C 1 278 ? -63.706 11.805  30.354  1   30.06  ? 274 ARG C N   1 
ATOM   6712 C  CA  . ARG C 1 278 ? -62.578 12.654  30.01   1   25.25  ? 274 ARG C CA  1 
ATOM   6713 C  C   . ARG C 1 278 ? -62.036 12.2    28.659  1   23.98  ? 274 ARG C C   1 
ATOM   6714 O  O   . ARG C 1 278 ? -61.931 11.005  28.405  1   24.35  ? 274 ARG C O   1 
ATOM   6715 C  CB  . ARG C 1 278 ? -61.512 12.553  31.115  1   26.23  ? 274 ARG C CB  1 
ATOM   6716 C  CG  . ARG C 1 278 ? -60.55  13.723  31.191  1   25.98  ? 274 ARG C CG  1 
ATOM   6717 C  CD  . ARG C 1 278 ? -59.59  13.571  32.352  1   26.54  ? 274 ARG C CD  1 
ATOM   6718 N  NE  . ARG C 1 278 ? -60.247 13.664  33.652  1   27.12  ? 274 ARG C NE  1 
ATOM   6719 C  CZ  . ARG C 1 278 ? -59.921 12.945  34.721  1   25.49  ? 274 ARG C CZ  1 
ATOM   6720 N  NH1 . ARG C 1 278 ? -58.812 12.228  34.761  1   26.11  ? 274 ARG C NH1 1 
ATOM   6721 N  NH2 . ARG C 1 278 ? -60.736 12.937  35.772  1   25.66  ? 274 ARG C NH2 1 
ATOM   6722 N  N   . ILE C 1 279 ? -61.714 13.162  27.79   1   23.78  ? 275 ILE C N   1 
ATOM   6723 C  CA  . ILE C 1 279 ? -61.277 12.861  26.439  1   23.76  ? 275 ILE C CA  1 
ATOM   6724 C  C   . ILE C 1 279 ? -59.939 12.119  26.451  1   26.97  ? 275 ILE C C   1 
ATOM   6725 O  O   . ILE C 1 279 ? -59.101 12.348  27.32   1   25.86  ? 275 ILE C O   1 
ATOM   6726 C  CB  . ILE C 1 279 ? -61.229 14.173  25.626  1   23.52  ? 275 ILE C CB  1 
ATOM   6727 C  CG1 . ILE C 1 279 ? -61.21  13.895  24.131  1   24.17  ? 275 ILE C CG1 1 
ATOM   6728 C  CG2 . ILE C 1 279 ? -60.061 15.061  26.04   1   24.23  ? 275 ILE C CG2 1 
ATOM   6729 C  CD1 . ILE C 1 279 ? -61.376 15.131  23.296  1   24.73  ? 275 ILE C CD1 1 
ATOM   6730 N  N   . SER C 1 280 ? -59.762 11.196  25.498  1   28.36  ? 276 SER C N   1 
ATOM   6731 C  CA  . SER C 1 280 ? -58.484 10.533  25.301  1   30.49  ? 276 SER C CA  1 
ATOM   6732 C  C   . SER C 1 280 ? -57.555 11.409  24.464  1   31.79  ? 276 SER C C   1 
ATOM   6733 O  O   . SER C 1 280 ? -58.017 12.321  23.783  1   28.11  ? 276 SER C O   1 
ATOM   6734 C  CB  . SER C 1 280 ? -58.683 9.208   24.596  1   29.78  ? 276 SER C CB  1 
ATOM   6735 O  OG  . SER C 1 280 ? -59.229 9.442   23.311  1   29.21  ? 276 SER C OG  1 
ATOM   6736 N  N   . ALA C 1 281 ? -56.25  11.111  24.511  1   33.85  ? 277 ALA C N   1 
ATOM   6737 C  CA  . ALA C 1 281 ? -55.278 11.819  23.692  1   34.02  ? 277 ALA C CA  1 
ATOM   6738 C  C   . ALA C 1 281 ? -55.6   11.612  22.215  1   31.17  ? 277 ALA C C   1 
ATOM   6739 O  O   . ALA C 1 281 ? -55.572 12.564  21.449  1   30.23  ? 277 ALA C O   1 
ATOM   6740 C  CB  . ALA C 1 281 ? -53.855 11.366  23.992  1   34.03  ? 277 ALA C CB  1 
ATOM   6741 N  N   . LYS C 1 282 ? -55.901 10.368  21.837  1   31.84  ? 278 LYS C N   1 
ATOM   6742 C  CA  . LYS C 1 282 ? -56.337 10.044  20.487  1   32.52  ? 278 LYS C CA  1 
ATOM   6743 C  C   . LYS C 1 282 ? -57.466 10.945  19.991  1   33.18  ? 278 LYS C C   1 
ATOM   6744 O  O   . LYS C 1 282 ? -57.362 11.544  18.922  1   33.72  ? 278 LYS C O   1 
ATOM   6745 C  CB  . LYS C 1 282 ? -56.839 8.589   20.401  1   36.55  ? 278 LYS C CB  1 
ATOM   6746 C  CG  . LYS C 1 282 ? -55.885 7.619   19.777  1   40.38  ? 278 LYS C CG  1 
ATOM   6747 C  CD  . LYS C 1 282 ? -56.544 6.277   19.508  1   40.74  ? 278 LYS C CD  1 
ATOM   6748 C  CE  . LYS C 1 282 ? -55.487 5.247   19.202  1   42.58  ? 278 LYS C CE  1 
ATOM   6749 N  NZ  . LYS C 1 282 ? -56.02  3.878   19.169  1   43.55  ? 278 LYS C NZ  1 
ATOM   6750 N  N   . ALA C 1 283 ? -58.545 11.039  20.781  1   31     ? 279 ALA C N   1 
ATOM   6751 C  CA  . ALA C 1 283 ? -59.717 11.817  20.406  1   31.64  ? 279 ALA C CA  1 
ATOM   6752 C  C   . ALA C 1 283 ? -59.441 13.318  20.37   1   32.64  ? 279 ALA C C   1 
ATOM   6753 O  O   . ALA C 1 283 ? -59.967 14.021  19.511  1   36.28  ? 279 ALA C O   1 
ATOM   6754 C  CB  . ALA C 1 283 ? -60.881 11.533  21.352  1   30.37  ? 279 ALA C CB  1 
ATOM   6755 N  N   . ALA C 1 284 ? -58.62  13.805  21.307  1   31.51  ? 280 ALA C N   1 
ATOM   6756 C  CA  . ALA C 1 284 ? -58.267 15.213  21.358  1   31.54  ? 280 ALA C CA  1 
ATOM   6757 C  C   . ALA C 1 284 ? -57.503 15.673  20.117  1   32.88  ? 280 ALA C C   1 
ATOM   6758 O  O   . ALA C 1 284 ? -57.68  16.803  19.668  1   36.17  ? 280 ALA C O   1 
ATOM   6759 C  CB  . ALA C 1 284 ? -57.463 15.5    22.609  1   32.03  ? 280 ALA C CB  1 
ATOM   6760 N  N   . LEU C 1 285 ? -56.679 14.794  19.543  1   32.71  ? 281 LEU C N   1 
ATOM   6761 C  CA  . LEU C 1 285 ? -55.938 15.116  18.331  1   33.5   ? 281 LEU C CA  1 
ATOM   6762 C  C   . LEU C 1 285 ? -56.852 15.534  17.18   1   34.75  ? 281 LEU C C   1 
ATOM   6763 O  O   . LEU C 1 285 ? -56.439 16.292  16.305  1   32.97  ? 281 LEU C O   1 
ATOM   6764 C  CB  . LEU C 1 285 ? -55.098 13.906  17.881  1   34.11  ? 281 LEU C CB  1 
ATOM   6765 C  CG  . LEU C 1 285 ? -53.84  13.613  18.693  1   34.17  ? 281 LEU C CG  1 
ATOM   6766 C  CD1 . LEU C 1 285 ? -53.098 12.4    18.14   1   33.41  ? 281 LEU C CD1 1 
ATOM   6767 C  CD2 . LEU C 1 285 ? -52.908 14.826  18.714  1   32.97  ? 281 LEU C CD2 1 
ATOM   6768 N  N   . ALA C 1 286 ? -58.091 15.02   17.184  1   35.14  ? 282 ALA C N   1 
ATOM   6769 C  CA  . ALA C 1 286 ? -59.071 15.34   16.158  1   31.49  ? 282 ALA C CA  1 
ATOM   6770 C  C   . ALA C 1 286 ? -59.937 16.548  16.508  1   31.79  ? 282 ALA C C   1 
ATOM   6771 O  O   . ALA C 1 286 ? -60.78  16.939  15.712  1   29.94  ? 282 ALA C O   1 
ATOM   6772 C  CB  . ALA C 1 286 ? -59.967 14.142  15.917  1   29.22  ? 282 ALA C CB  1 
ATOM   6773 N  N   . HIS C 1 287 ? -59.746 17.143  17.693  1   31.8   ? 283 HIS C N   1 
ATOM   6774 C  CA  . HIS C 1 287 ? -60.608 18.241  18.102  1   31.37  ? 283 HIS C CA  1 
ATOM   6775 C  C   . HIS C 1 287 ? -60.452 19.429  17.15   1   30.53  ? 283 HIS C C   1 
ATOM   6776 O  O   . HIS C 1 287 ? -59.352 19.697  16.671  1   30.24  ? 283 HIS C O   1 
ATOM   6777 C  CB  . HIS C 1 287 ? -60.326 18.632  19.549  1   30.08  ? 283 HIS C CB  1 
ATOM   6778 C  CG  . HIS C 1 287 ? -61.318 19.593  20.127  1   30.14  ? 283 HIS C CG  1 
ATOM   6779 N  ND1 . HIS C 1 287 ? -61.353 20.911  19.728  1   30.62  ? 283 HIS C ND1 1 
ATOM   6780 C  CD2 . HIS C 1 287 ? -62.267 19.395  21.071  1   29.73  ? 283 HIS C CD2 1 
ATOM   6781 C  CE1 . HIS C 1 287 ? -62.331 21.478  20.428  1   30.65  ? 283 HIS C CE1 1 
ATOM   6782 N  NE2 . HIS C 1 287 ? -62.905 20.596  21.255  1   29.4   ? 283 HIS C NE2 1 
ATOM   6783 N  N   . PRO C 1 288 ? -61.547 20.155  16.815  1   30.88  ? 284 PRO C N   1 
ATOM   6784 C  CA  . PRO C 1 288 ? -61.465 21.318  15.923  1   31.51  ? 284 PRO C CA  1 
ATOM   6785 C  C   . PRO C 1 288 ? -60.43  22.377  16.285  1   29.82  ? 284 PRO C C   1 
ATOM   6786 O  O   . PRO C 1 288 ? -59.995 23.135  15.418  1   31.63  ? 284 PRO C O   1 
ATOM   6787 C  CB  . PRO C 1 288 ? -62.879 21.928  15.989  1   31.24  ? 284 PRO C CB  1 
ATOM   6788 C  CG  . PRO C 1 288 ? -63.765 20.789  16.377  1   31.11  ? 284 PRO C CG  1 
ATOM   6789 C  CD  . PRO C 1 288 ? -62.932 19.846  17.213  1   31.73  ? 284 PRO C CD  1 
ATOM   6790 N  N   . PHE C 1 289 ? -60.036 22.433  17.559  1   29.51  ? 285 PHE C N   1 
ATOM   6791 C  CA  . PHE C 1 289 ? -58.986 23.346  17.978  1   31.13  ? 285 PHE C CA  1 
ATOM   6792 C  C   . PHE C 1 289 ? -57.722 23.22   17.122  1   31.08  ? 285 PHE C C   1 
ATOM   6793 O  O   . PHE C 1 289 ? -57.059 24.215  16.85   1   30.94  ? 285 PHE C O   1 
ATOM   6794 C  CB  . PHE C 1 289 ? -58.659 23.114  19.455  1   31.83  ? 285 PHE C CB  1 
ATOM   6795 C  CG  . PHE C 1 289 ? -57.648 24.068  20.051  1   30.16  ? 285 PHE C CG  1 
ATOM   6796 C  CD1 . PHE C 1 289 ? -57.917 25.417  20.141  1   29.67  ? 285 PHE C CD1 1 
ATOM   6797 C  CD2 . PHE C 1 289 ? -56.446 23.607  20.544  1   29.08  ? 285 PHE C CD2 1 
ATOM   6798 C  CE1 . PHE C 1 289 ? -56.995 26.285  20.713  1   29.56  ? 285 PHE C CE1 1 
ATOM   6799 C  CE2 . PHE C 1 289 ? -55.529 24.47   21.117  1   29.64  ? 285 PHE C CE2 1 
ATOM   6800 C  CZ  . PHE C 1 289 ? -55.813 25.803  21.212  1   29.46  ? 285 PHE C CZ  1 
ATOM   6801 N  N   . PHE C 1 290 ? -57.413 21.997  16.676  1   32.23  ? 286 PHE C N   1 
ATOM   6802 C  CA  . PHE C 1 290 ? -56.181 21.726  15.951  1   34.73  ? 286 PHE C CA  1 
ATOM   6803 C  C   . PHE C 1 290 ? -56.265 21.819  14.427  1   37.89  ? 286 PHE C C   1 
ATOM   6804 O  O   . PHE C 1 290 ? -55.274 21.588  13.744  1   38.59  ? 286 PHE C O   1 
ATOM   6805 C  CB  . PHE C 1 290 ? -55.684 20.327  16.343  1   33.87  ? 286 PHE C CB  1 
ATOM   6806 C  CG  . PHE C 1 290 ? -55.337 20.235  17.805  1   33.45  ? 286 PHE C CG  1 
ATOM   6807 C  CD1 . PHE C 1 290 ? -54.353 21.043  18.354  1   31.43  ? 286 PHE C CD1 1 
ATOM   6808 C  CD2 . PHE C 1 290 ? -56.012 19.366  18.637  1   33.96  ? 286 PHE C CD2 1 
ATOM   6809 C  CE1 . PHE C 1 290 ? -54.036 20.954  19.702  1   32.35  ? 286 PHE C CE1 1 
ATOM   6810 C  CE2 . PHE C 1 290 ? -55.693 19.289  19.991  1   35.46  ? 286 PHE C CE2 1 
ATOM   6811 C  CZ  . PHE C 1 290 ? -54.712 20.081  20.515  1   33.51  ? 286 PHE C CZ  1 
ATOM   6812 N  N   . GLN C 1 291 ? -57.425 22.196  13.885  1   41.19  ? 287 GLN C N   1 
ATOM   6813 C  CA  . GLN C 1 291 ? -57.592 22.199  12.441  1   43.58  ? 287 GLN C CA  1 
ATOM   6814 C  C   . GLN C 1 291 ? -56.582 23.072  11.698  1   40.1   ? 287 GLN C C   1 
ATOM   6815 O  O   . GLN C 1 291 ? -56.186 22.736  10.585  1   37.32  ? 287 GLN C O   1 
ATOM   6816 C  CB  . GLN C 1 291 ? -59.042 22.575  12.054  1   47.55  ? 287 GLN C CB  1 
ATOM   6817 C  CG  . GLN C 1 291 ? -60.038 21.496  12.489  1   53.3   ? 287 GLN C CG  1 
ATOM   6818 C  CD  . GLN C 1 291 ? -61.479 21.845  12.199  1   59.97  ? 287 GLN C CD  1 
ATOM   6819 O  OE1 . GLN C 1 291 ? -61.86  23.017  12.097  1   61.64  ? 287 GLN C OE1 1 
ATOM   6820 N  NE2 . GLN C 1 291 ? -62.306 20.819  12.066  1   60.89  ? 287 GLN C NE2 1 
ATOM   6821 N  N   . ASP C 1 292 ? -56.142 24.164  12.324  1   40.48  ? 288 ASP C N   1 
ATOM   6822 C  CA  . ASP C 1 292 ? -55.232 25.102  11.683  1   39.95  ? 288 ASP C CA  1 
ATOM   6823 C  C   . ASP C 1 292 ? -53.844 25.092  12.325  1   40.56  ? 288 ASP C C   1 
ATOM   6824 O  O   . ASP C 1 292 ? -53.115 26.079  12.253  1   43.31  ? 288 ASP C O   1 
ATOM   6825 C  CB  . ASP C 1 292 ? -55.839 26.531  11.734  1   39.57  ? 288 ASP C CB  1 
ATOM   6826 C  CG  . ASP C 1 292 ? -56.126 27.036  13.136  1   39.71  ? 288 ASP C CG  1 
ATOM   6827 O  OD1 . ASP C 1 292 ? -55.868 26.285  14.096  1   39.75  ? 288 ASP C OD1 1 
ATOM   6828 O  OD2 . ASP C 1 292 ? -56.615 28.176  13.267  1   39.7   ? 288 ASP C OD2 1 
ATOM   6829 N  N   . VAL C 1 293 ? -53.484 23.973  12.967  1   36.21  ? 289 VAL C N   1 
ATOM   6830 C  CA  . VAL C 1 293 ? -52.235 23.887  13.705  1   34.77  ? 289 VAL C CA  1 
ATOM   6831 C  C   . VAL C 1 293 ? -51.061 23.971  12.732  1   35.51  ? 289 VAL C C   1 
ATOM   6832 O  O   . VAL C 1 293 ? -51.088 23.348  11.674  1   38.07  ? 289 VAL C O   1 
ATOM   6833 C  CB  . VAL C 1 293 ? -52.17  22.601  14.583  1   33.04  ? 289 VAL C CB  1 
ATOM   6834 C  CG1 . VAL C 1 293 ? -52.143 21.332  13.73   1   33.17  ? 289 VAL C CG1 1 
ATOM   6835 C  CG2 . VAL C 1 293 ? -50.976 22.634  15.536  1   31.8   ? 289 VAL C CG2 1 
ATOM   6836 N  N   . THR C 1 294 ? -50.051 24.77   13.096  1   34.88  ? 290 THR C N   1 
ATOM   6837 C  CA  . THR C 1 294 ? -48.771 24.804  12.405  1   34.38  ? 290 THR C CA  1 
ATOM   6838 C  C   . THR C 1 294 ? -47.684 24.449  13.417  1   32.62  ? 290 THR C C   1 
ATOM   6839 O  O   . THR C 1 294 ? -47.994 24.011  14.518  1   34.29  ? 290 THR C O   1 
ATOM   6840 C  CB  . THR C 1 294 ? -48.562 26.172  11.744  1   35.11  ? 290 THR C CB  1 
ATOM   6841 O  OG1 . THR C 1 294 ? -48.618 27.181  12.752  1   34.81  ? 290 THR C OG1 1 
ATOM   6842 C  CG2 . THR C 1 294 ? -49.6   26.462  10.676  1   36.6   ? 290 THR C CG2 1 
ATOM   6843 N  N   . LYS C 1 295 ? -46.418 24.63   13.026  1   33.92  ? 291 LYS C N   1 
ATOM   6844 C  CA  . LYS C 1 295 ? -45.274 24.399  13.894  1   36.99  ? 291 LYS C CA  1 
ATOM   6845 C  C   . LYS C 1 295 ? -44.355 25.622  13.914  1   36.24  ? 291 LYS C C   1 
ATOM   6846 O  O   . LYS C 1 295 ? -43.301 25.615  13.278  1   35.6   ? 291 LYS C O   1 
ATOM   6847 C  CB  . LYS C 1 295 ? -44.48  23.154  13.415  1   40.43  ? 291 LYS C CB  1 
ATOM   6848 C  CG  . LYS C 1 295 ? -43.348 22.737  14.37   1   46.25  ? 291 LYS C CG  1 
ATOM   6849 C  CD  . LYS C 1 295 ? -42.483 21.567  13.877  1   49.63  ? 291 LYS C CD  1 
ATOM   6850 C  CE  . LYS C 1 295 ? -41.445 21.208  14.925  1   50.6   ? 291 LYS C CE  1 
ATOM   6851 N  NZ  . LYS C 1 295 ? -40.523 20.129  14.483  1   50.33  ? 291 LYS C NZ  1 
ATOM   6852 N  N   . PRO C 1 296 ? -44.701 26.708  14.647  1   36.06  ? 292 PRO C N   1 
ATOM   6853 C  CA  . PRO C 1 296 ? -43.82  27.88   14.721  1   36.37  ? 292 PRO C CA  1 
ATOM   6854 C  C   . PRO C 1 296 ? -42.593 27.6    15.59   1   35.38  ? 292 PRO C C   1 
ATOM   6855 O  O   . PRO C 1 296 ? -42.571 26.619  16.328  1   31.7   ? 292 PRO C O   1 
ATOM   6856 C  CB  . PRO C 1 296 ? -44.728 28.978  15.295  1   35.96  ? 292 PRO C CB  1 
ATOM   6857 C  CG  . PRO C 1 296 ? -45.827 28.241  16.029  1   35.88  ? 292 PRO C CG  1 
ATOM   6858 C  CD  . PRO C 1 296 ? -45.942 26.857  15.43   1   35.37  ? 292 PRO C CD  1 
ATOM   6859 N  N   . VAL C 1 297 ? -41.557 28.437  15.455  1   36.13  ? 293 VAL C N   1 
ATOM   6860 C  CA  . VAL C 1 297 ? -40.387 28.348  16.317  1   38.81  ? 293 VAL C CA  1 
ATOM   6861 C  C   . VAL C 1 297 ? -40.62  29.328  17.466  1   38.19  ? 293 VAL C C   1 
ATOM   6862 O  O   . VAL C 1 297 ? -41.208 30.386  17.268  1   38.83  ? 293 VAL C O   1 
ATOM   6863 C  CB  . VAL C 1 297 ? -39.018 28.587  15.565  1   38.75  ? 293 VAL C CB  1 
ATOM   6864 C  CG1 . VAL C 1 297 ? -39.017 27.93   14.19   1   35.45  ? 293 VAL C CG1 1 
ATOM   6865 C  CG2 . VAL C 1 297 ? -38.66  30.064  15.441  1   41.04  ? 293 VAL C CG2 1 
ATOM   6866 N  N   . PRO C 1 298 ? -40.204 29.007  18.712  1   38.53  ? 294 PRO C N   1 
ATOM   6867 C  CA  . PRO C 1 298 ? -40.285 29.967  19.815  1   40.59  ? 294 PRO C CA  1 
ATOM   6868 C  C   . PRO C 1 298 ? -39.223 31.062  19.735  1   45.07  ? 294 PRO C C   1 
ATOM   6869 O  O   . PRO C 1 298 ? -38.182 30.879  19.109  1   45.56  ? 294 PRO C O   1 
ATOM   6870 C  CB  . PRO C 1 298 ? -40.075 29.078  21.043  1   40.16  ? 294 PRO C CB  1 
ATOM   6871 C  CG  . PRO C 1 298 ? -39.207 27.955  20.542  1   38.84  ? 294 PRO C CG  1 
ATOM   6872 C  CD  . PRO C 1 298 ? -39.641 27.712  19.118  1   37.15  ? 294 PRO C CD  1 
ATOM   6873 N  N   . HIS C 1 299 ? -39.485 32.199  20.387  1   54.75  ? 295 HIS C N   1 
ATOM   6874 C  CA  . HIS C 1 299 ? -38.464 33.219  20.567  1   63.45  ? 295 HIS C CA  1 
ATOM   6875 C  C   . HIS C 1 299 ? -37.616 32.895  21.801  1   67.97  ? 295 HIS C C   1 
ATOM   6876 O  O   . HIS C 1 299 ? -38.045 33.145  22.927  1   72.54  ? 295 HIS C O   1 
ATOM   6877 C  CB  . HIS C 1 299 ? -39.105 34.612  20.673  1   67.44  ? 295 HIS C CB  1 
ATOM   6878 C  CG  . HIS C 1 299 ? -38.11  35.733  20.653  1   78.19  ? 295 HIS C CG  1 
ATOM   6879 N  ND1 . HIS C 1 299 ? -37.311 35.972  19.542  1   82.68  ? 295 HIS C ND1 1 
ATOM   6880 C  CD2 . HIS C 1 299 ? -37.807 36.641  21.608  1   78.67  ? 295 HIS C CD2 1 
ATOM   6881 C  CE1 . HIS C 1 299 ? -36.554 37.015  19.853  1   81.34  ? 295 HIS C CE1 1 
ATOM   6882 N  NE2 . HIS C 1 299 ? -36.821 37.45   21.091  1   82.37  ? 295 HIS C NE2 1 
ATOM   6883 N  N   . LEU C 1 300 ? -36.413 32.338  21.569  1   67.27  ? 296 LEU C N   1 
ATOM   6884 C  CA  . LEU C 1 300 ? -35.505 31.899  22.624  1   67.8   ? 296 LEU C CA  1 
ATOM   6885 C  C   . LEU C 1 300 ? -34.238 32.775  22.767  1   71.89  ? 296 LEU C C   1 
ATOM   6886 O  O   . LEU C 1 300 ? -33.515 32.653  23.761  1   69.95  ? 296 LEU C O   1 
ATOM   6887 C  CB  . LEU C 1 300 ? -35.044 30.46   22.343  1   62.41  ? 296 LEU C CB  1 
ATOM   6888 C  CG  . LEU C 1 300 ? -36.107 29.382  22.46   1   60.67  ? 296 LEU C CG  1 
ATOM   6889 C  CD1 . LEU C 1 300 ? -35.611 28.082  21.914  1   55.58  ? 296 LEU C CD1 1 
ATOM   6890 C  CD2 . LEU C 1 300 ? -36.546 29.189  23.9    1   63.46  ? 296 LEU C CD2 1 
ATOM   6891 N  N   . GLY D 2 1   ? -65.214 1.195   30.841  1   35.1   ? 171 GLY D N   1 
ATOM   6892 C  CA  . GLY D 2 1   ? -64.771 2.58    30.936  1   35.59  ? 171 GLY D CA  1 
ATOM   6893 C  C   . GLY D 2 1   ? -63.257 2.674   30.787  1   34.16  ? 171 GLY D C   1 
ATOM   6894 O  O   . GLY D 2 1   ? -62.634 1.742   30.285  1   33.35  ? 171 GLY D O   1 
ATOM   6895 N  N   . VAL D 2 2   ? -62.681 3.788   31.252  1   32.25  ? 172 VAL D N   1 
ATOM   6896 C  CA  . VAL D 2 2   ? -61.285 4.101   30.986  1   32.27  ? 172 VAL D CA  1 
ATOM   6897 C  C   . VAL D 2 2   ? -60.317 3.078   31.586  1   31.82  ? 172 VAL D C   1 
ATOM   6898 O  O   . VAL D 2 2   ? -59.213 2.901   31.075  1   30.59  ? 172 VAL D O   1 
ATOM   6899 C  CB  . VAL D 2 2   ? -60.971 5.554   31.455  1   32.91  ? 172 VAL D CB  1 
ATOM   6900 C  CG1 . VAL D 2 2   ? -60.942 5.676   32.979  1   31.68  ? 172 VAL D CG1 1 
ATOM   6901 C  CG2 . VAL D 2 2   ? -59.671 6.061   30.849  1   32.78  ? 172 VAL D CG2 1 
ATOM   6902 N  N   . ASN D 2 3   ? -60.738 2.369   32.643  1   31.43  ? 173 ASN D N   1 
ATOM   6903 C  CA  . ASN D 2 3   ? -59.924 1.302   33.209  1   30.92  ? 173 ASN D CA  1 
ATOM   6904 C  C   . ASN D 2 3   ? -59.7   0.132   32.253  1   30.68  ? 173 ASN D C   1 
ATOM   6905 O  O   . ASN D 2 3   ? -58.794 -0.669  32.465  1   28.31  ? 173 ASN D O   1 
ATOM   6906 C  CB  . ASN D 2 3   ? -60.55  0.791   34.5    1   32.12  ? 173 ASN D CB  1 
ATOM   6907 C  CG  . ASN D 2 3   ? -60.56  1.834   35.58   1   31.62  ? 173 ASN D CG  1 
ATOM   6908 O  OD1 . ASN D 2 3   ? -59.816 2.816   35.527  1   33.26  ? 173 ASN D OD1 1 
ATOM   6909 N  ND2 . ASN D 2 3   ? -61.387 1.645   36.588  1   30.93  ? 173 ASN D ND2 1 
ATOM   6910 N  N   . GLU D 2 4   ? -60.539 0.041   31.211  1   31.75  ? 174 GLU D N   1 
ATOM   6911 C  CA  . GLU D 2 4   ? -60.353 -0.918  30.134  1   34.83  ? 174 GLU D CA  1 
ATOM   6912 C  C   . GLU D 2 4   ? -59.812 -0.277  28.856  1   35.55  ? 174 GLU D C   1 
ATOM   6913 O  O   . GLU D 2 4   ? -59.8   -0.92   27.809  1   34.55  ? 174 GLU D O   1 
ATOM   6914 C  CB  . GLU D 2 4   ? -61.694 -1.593  29.83   1   37.64  ? 174 GLU D CB  1 
ATOM   6915 C  CG  . GLU D 2 4   ? -62.314 -2.263  31.044  1   39.64  ? 174 GLU D CG  1 
ATOM   6916 C  CD  . GLU D 2 4   ? -63.695 -2.839  30.821  1   41.74  ? 174 GLU D CD  1 
ATOM   6917 O  OE1 . GLU D 2 4   ? -64.28  -2.59   29.741  1   41.55  ? 174 GLU D OE1 1 
ATOM   6918 O  OE2 . GLU D 2 4   ? -64.192 -3.538  31.733  1   42.1   ? 174 GLU D OE2 1 
ATOM   6919 N  N   . VAL D 2 5   ? -59.352 0.982   28.958  1   35.78  ? 175 VAL D N   1 
ATOM   6920 C  CA  . VAL D 2 5   ? -58.801 1.748   27.845  1   31.89  ? 175 VAL D CA  1 
ATOM   6921 C  C   . VAL D 2 5   ? -59.445 1.419   26.499  1   31.01  ? 175 VAL D C   1 
ATOM   6922 O  O   . VAL D 2 5   ? -58.803 0.865   25.61   1   29.92  ? 175 VAL D O   1 
ATOM   6923 C  CB  . VAL D 2 5   ? -57.247 1.606   27.799  1   31.83  ? 175 VAL D CB  1 
ATOM   6924 C  CG1 . VAL D 2 5   ? -56.608 2.255   29.02   1   31.99  ? 175 VAL D CG1 1 
ATOM   6925 C  CG2 . VAL D 2 5   ? -56.788 0.152   27.679  1   32.41  ? 175 VAL D CG2 1 
ATOM   6926 N  N   . PRO D 2 6   ? -60.729 1.793   26.289  1   32.01  ? 176 PRO D N   1 
ATOM   6927 C  CA  . PRO D 2 6   ? -61.421 1.498   25.033  1   31.55  ? 176 PRO D CA  1 
ATOM   6928 C  C   . PRO D 2 6   ? -60.69  2.02    23.798  1   32.36  ? 176 PRO D C   1 
ATOM   6929 O  O   . PRO D 2 6   ? -60.652 1.353   22.764  1   34.68  ? 176 PRO D O   1 
ATOM   6930 C  CB  . PRO D 2 6   ? -62.772 2.212   25.177  1   31.15  ? 176 PRO D CB  1 
ATOM   6931 C  CG  . PRO D 2 6   ? -62.899 2.585   26.613  1   31.79  ? 176 PRO D CG  1 
ATOM   6932 C  CD  . PRO D 2 6   ? -61.546 2.578   27.232  1   33.62  ? 176 PRO D CD  1 
ATOM   6933 N  N   . ASP D 2 7   ? -60.122 3.226   23.913  1   31.27  ? 177 ASP D N   1 
ATOM   6934 C  CA  . ASP D 2 7   ? -59.466 3.873   22.788  1   30.55  ? 177 ASP D CA  1 
ATOM   6935 C  C   . ASP D 2 7   ? -58.09  3.302   22.447  1   28.45  ? 177 ASP D C   1 
ATOM   6936 O  O   . ASP D 2 7   ? -57.53  3.675   21.423  1   26.81  ? 177 ASP D O   1 
ATOM   6937 C  CB  . ASP D 2 7   ? -59.309 5.393   23.054  1   30.99  ? 177 ASP D CB  1 
ATOM   6938 C  CG  . ASP D 2 7   ? -60.552 6.187   22.821  1   29.5   ? 177 ASP D CG  1 
ATOM   6939 O  OD1 . ASP D 2 7   ? -61.289 5.849   21.896  1   30.49  ? 177 ASP D OD1 1 
ATOM   6940 O  OD2 . ASP D 2 7   ? -60.76  7.192   23.538  1   29.73  ? 177 ASP D OD2 1 
ATOM   6941 N  N   . TYR D 2 8   ? -57.552 2.42    23.304  1   28.55  ? 178 TYR D N   1 
ATOM   6942 C  CA  . TYR D 2 8   ? -56.199 1.907   23.139  1   28.8   ? 178 TYR D CA  1 
ATOM   6943 C  C   . TYR D 2 8   ? -56.05  0.391   23.197  1   30.37  ? 178 TYR D C   1 
ATOM   6944 O  O   . TYR D 2 8   ? -54.986 -0.109  22.855  1   27.38  ? 178 TYR D O   1 
ATOM   6945 C  CB  . TYR D 2 8   ? -55.268 2.521   24.213  1   26.14  ? 178 TYR D CB  1 
ATOM   6946 C  CG  . TYR D 2 8   ? -55.197 4.02    24.128  1   26.46  ? 178 TYR D CG  1 
ATOM   6947 C  CD1 . TYR D 2 8   ? -54.467 4.646   23.132  1   25.51  ? 178 TYR D CD1 1 
ATOM   6948 C  CD2 . TYR D 2 8   ? -55.918 4.816   25      1   28.72  ? 178 TYR D CD2 1 
ATOM   6949 C  CE1 . TYR D 2 8   ? -54.42  6.03    23.032  1   26.64  ? 178 TYR D CE1 1 
ATOM   6950 C  CE2 . TYR D 2 8   ? -55.867 6.204   24.923  1   27.65  ? 178 TYR D CE2 1 
ATOM   6951 C  CZ  . TYR D 2 8   ? -55.12  6.811   23.934  1   26.3   ? 178 TYR D CZ  1 
ATOM   6952 O  OH  . TYR D 2 8   ? -55.08  8.19    23.836  1   24.87  ? 178 TYR D OH  1 
ATOM   6953 N  N   . HIS D 2 9   ? -57.088 -0.347  23.621  1   34.35  ? 179 HIS D N   1 
ATOM   6954 C  CA  . HIS D 2 9   ? -56.912 -1.77   23.896  1   39.98  ? 179 HIS D CA  1 
ATOM   6955 C  C   . HIS D 2 9   ? -56.51  -2.578  22.655  1   38.7   ? 179 HIS D C   1 
ATOM   6956 O  O   . HIS D 2 9   ? -55.762 -3.543  22.772  1   35.64  ? 179 HIS D O   1 
ATOM   6957 C  CB  . HIS D 2 9   ? -58.156 -2.392  24.604  1   40.32  ? 179 HIS D CB  1 
ATOM   6958 C  CG  . HIS D 2 9   ? -59.311 -2.724  23.71   1   40.72  ? 179 HIS D CG  1 
ATOM   6959 N  ND1 . HIS D 2 9   ? -59.633 -4.036  23.414  1   43.92  ? 179 HIS D ND1 1 
ATOM   6960 C  CD2 . HIS D 2 9   ? -60.177 -1.906  23.069  1   46.57  ? 179 HIS D CD2 1 
ATOM   6961 C  CE1 . HIS D 2 9   ? -60.68  -3.985  22.596  1   46.38  ? 179 HIS D CE1 1 
ATOM   6962 N  NE2 . HIS D 2 9   ? -61.044 -2.714  22.361  1   45.33  ? 179 HIS D NE2 1 
ATOM   6963 N  N   . GLU D 2 10  ? -56.987 -2.169  21.469  1   38.99  ? 180 GLU D N   1 
ATOM   6964 C  CA  . GLU D 2 10  ? -56.634 -2.823  20.217  1   40.19  ? 180 GLU D CA  1 
ATOM   6965 C  C   . GLU D 2 10  ? -55.179 -2.55   19.834  1   37.35  ? 180 GLU D C   1 
ATOM   6966 O  O   . GLU D 2 10  ? -54.431 -3.477  19.522  1   38.01  ? 180 GLU D O   1 
ATOM   6967 C  CB  . GLU D 2 10  ? -57.58  -2.359  19.101  1   43.26  ? 180 GLU D CB  1 
ATOM   6968 C  CG  . GLU D 2 10  ? -57.622 -3.253  17.872  1   46.56  ? 180 GLU D CG  1 
ATOM   6969 C  CD  . GLU D 2 10  ? -58.462 -2.712  16.724  1   50.74  ? 180 GLU D CD  1 
ATOM   6970 O  OE1 . GLU D 2 10  ? -59.161 -1.688  16.908  1   54.07  ? 180 GLU D OE1 1 
ATOM   6971 O  OE2 . GLU D 2 10  ? -58.407 -3.307  15.625  1   50.3   ? 180 GLU D OE2 1 
ATOM   6972 N  N   . ASP D 2 11  ? -54.785 -1.272  19.856  1   34.24  ? 181 ASP D N   1 
ATOM   6973 C  CA  . ASP D 2 11  ? -53.394 -0.898  19.645  1   33.08  ? 181 ASP D CA  1 
ATOM   6974 C  C   . ASP D 2 11  ? -52.478 -1.635  20.621  1   33.07  ? 181 ASP D C   1 
ATOM   6975 O  O   . ASP D 2 11  ? -51.434 -2.147  20.225  1   37.19  ? 181 ASP D O   1 
ATOM   6976 C  CB  . ASP D 2 11  ? -53.203 0.622   19.782  1   31.4   ? 181 ASP D CB  1 
ATOM   6977 C  CG  . ASP D 2 11  ? -53.716 1.472   18.623  1   31.92  ? 181 ASP D CG  1 
ATOM   6978 O  OD1 . ASP D 2 11  ? -54.15  0.891   17.599  1   29.22  ? 181 ASP D OD1 1 
ATOM   6979 O  OD2 . ASP D 2 11  ? -53.669 2.728   18.736  1   30.45  ? 181 ASP D OD2 1 
ATOM   6980 N  N   . ILE D 2 12  ? -52.89  -1.71   21.892  1   28.82  ? 182 ILE D N   1 
ATOM   6981 C  CA  . ILE D 2 12  ? -52.089 -2.355  22.914  1   29.25  ? 182 ILE D CA  1 
ATOM   6982 C  C   . ILE D 2 12  ? -51.951 -3.842  22.628  1   29.21  ? 182 ILE D C   1 
ATOM   6983 O  O   . ILE D 2 12  ? -50.851 -4.368  22.724  1   32.26  ? 182 ILE D O   1 
ATOM   6984 C  CB  . ILE D 2 12  ? -52.638 -2.104  24.343  1   29.37  ? 182 ILE D CB  1 
ATOM   6985 C  CG1 . ILE D 2 12  ? -52.397 -0.661  24.778  1   28.87  ? 182 ILE D CG1 1 
ATOM   6986 C  CG2 . ILE D 2 12  ? -52.024 -3.058  25.354  1   29.76  ? 182 ILE D CG2 1 
ATOM   6987 C  CD1 . ILE D 2 12  ? -53.344 -0.171  25.963  1   30.5   ? 182 ILE D CD1 1 
ATOM   6988 N  N   . HIS D 2 13  ? -53.065 -4.509  22.294  1   30.21  ? 183 HIS D N   1 
ATOM   6989 C  CA  . HIS D 2 13  ? -53.048 -5.923  21.944  1   27.99  ? 183 HIS D CA  1 
ATOM   6990 C  C   . HIS D 2 13  ? -52.113 -6.206  20.769  1   28.36  ? 183 HIS D C   1 
ATOM   6991 O  O   . HIS D 2 13  ? -51.303 -7.134  20.831  1   30.21  ? 183 HIS D O   1 
ATOM   6992 C  CB  . HIS D 2 13  ? -54.462 -6.431  21.626  1   28.58  ? 183 HIS D CB  1 
ATOM   6993 C  CG  . HIS D 2 13  ? -54.503 -7.862  21.188  1   29.09  ? 183 HIS D CG  1 
ATOM   6994 N  ND1 . HIS D 2 13  ? -54.319 -8.903  22.081  1   28.69  ? 183 HIS D ND1 1 
ATOM   6995 C  CD2 . HIS D 2 13  ? -54.688 -8.374  19.956  1   28.67  ? 183 HIS D CD2 1 
ATOM   6996 C  CE1 . HIS D 2 13  ? -54.398 -10.015 21.373  1   29.07  ? 183 HIS D CE1 1 
ATOM   6997 N  NE2 . HIS D 2 13  ? -54.624 -9.743  20.084  1   31.33  ? 183 HIS D NE2 1 
ATOM   6998 N  N   . THR D 2 14  ? -52.223 -5.399  19.705  1   26.31  ? 184 THR D N   1 
ATOM   6999 C  CA  . THR D 2 14  ? -51.353 -5.535  18.547  1   27.68  ? 184 THR D CA  1 
ATOM   7000 C  C   . THR D 2 14  ? -49.874 -5.401  18.906  1   30.39  ? 184 THR D C   1 
ATOM   7001 O  O   . THR D 2 14  ? -49.043 -6.166  18.424  1   32.11  ? 184 THR D O   1 
ATOM   7002 C  CB  . THR D 2 14  ? -51.737 -4.507  17.488  1   28.48  ? 184 THR D CB  1 
ATOM   7003 O  OG1 . THR D 2 14  ? -53.02  -4.848  16.97   1   29.96  ? 184 THR D OG1 1 
ATOM   7004 C  CG2 . THR D 2 14  ? -50.735 -4.44   16.346  1   28.49  ? 184 THR D CG2 1 
ATOM   7005 N  N   . TYR D 2 15  ? -49.562 -4.401  19.736  1   30.68  ? 185 TYR D N   1 
ATOM   7006 C  CA  . TYR D 2 15  ? -48.201 -4.149  20.17   1   30.65  ? 185 TYR D CA  1 
ATOM   7007 C  C   . TYR D 2 15  ? -47.664 -5.293  21.023  1   30.35  ? 185 TYR D C   1 
ATOM   7008 O  O   . TYR D 2 15  ? -46.513 -5.68   20.851  1   30.31  ? 185 TYR D O   1 
ATOM   7009 C  CB  . TYR D 2 15  ? -48.133 -2.835  20.955  1   31.44  ? 185 TYR D CB  1 
ATOM   7010 C  CG  . TYR D 2 15  ? -46.746 -2.489  21.427  1   31.78  ? 185 TYR D CG  1 
ATOM   7011 C  CD1 . TYR D 2 15  ? -45.706 -2.318  20.522  1   33.9   ? 185 TYR D CD1 1 
ATOM   7012 C  CD2 . TYR D 2 15  ? -46.467 -2.34   22.778  1   32.7   ? 185 TYR D CD2 1 
ATOM   7013 C  CE1 . TYR D 2 15  ? -44.425 -2.005  20.947  1   34.99  ? 185 TYR D CE1 1 
ATOM   7014 C  CE2 . TYR D 2 15  ? -45.193 -2.023  23.218  1   33.54  ? 185 TYR D CE2 1 
ATOM   7015 C  CZ  . TYR D 2 15  ? -44.17  -1.857  22.299  1   36.67  ? 185 TYR D CZ  1 
ATOM   7016 O  OH  . TYR D 2 15  ? -42.895 -1.54   22.71   1   39.19  ? 185 TYR D OH  1 
ATOM   7017 N  N   . LEU D 2 16  ? -48.484 -5.821  21.944  1   30.12  ? 186 LEU D N   1 
ATOM   7018 C  CA  . LEU D 2 16  ? -48.06  -6.922  22.801  1   30.98  ? 186 LEU D CA  1 
ATOM   7019 C  C   . LEU D 2 16  ? -47.75  -8.164  21.97   1   31     ? 186 LEU D C   1 
ATOM   7020 O  O   . LEU D 2 16  ? -46.798 -8.878  22.258  1   27.74  ? 186 LEU D O   1 
ATOM   7021 C  CB  . LEU D 2 16  ? -49.142 -7.27   23.838  1   31.21  ? 186 LEU D CB  1 
ATOM   7022 C  CG  . LEU D 2 16  ? -49.416 -6.213  24.883  1   33.26  ? 186 LEU D CG  1 
ATOM   7023 C  CD1 . LEU D 2 16  ? -50.51  -6.635  25.819  1   34.51  ? 186 LEU D CD1 1 
ATOM   7024 C  CD2 . LEU D 2 16  ? -48.164 -5.887  25.674  1   33.81  ? 186 LEU D CD2 1 
ATOM   7025 N  N   . ARG D 2 17  ? -48.557 -8.404  20.929  1   32.24  ? 187 ARG D N   1 
ATOM   7026 C  CA  . ARG D 2 17  ? -48.324 -9.521  20.029  1   33.67  ? 187 ARG D CA  1 
ATOM   7027 C  C   . ARG D 2 17  ? -46.968 -9.422  19.334  1   35.31  ? 187 ARG D C   1 
ATOM   7028 O  O   . ARG D 2 17  ? -46.301 -10.426 19.095  1   34.04  ? 187 ARG D O   1 
ATOM   7029 C  CB  . ARG D 2 17  ? -49.451 -9.607  18.989  1   31.55  ? 187 ARG D CB  1 
ATOM   7030 C  CG  . ARG D 2 17  ? -50.759 -10.156 19.549  1   30.29  ? 187 ARG D CG  1 
ATOM   7031 C  CD  . ARG D 2 17  ? -50.69  -11.652 19.849  1   29.62  ? 187 ARG D CD  1 
ATOM   7032 N  NE  . ARG D 2 17  ? -50.539 -12.457 18.642  1   30.08  ? 187 ARG D NE  1 
ATOM   7033 C  CZ  . ARG D 2 17  ? -51.531 -12.801 17.822  1   27.87  ? 187 ARG D CZ  1 
ATOM   7034 N  NH1 . ARG D 2 17  ? -52.794 -12.755 18.206  1   26.99  ? 187 ARG D NH1 1 
ATOM   7035 N  NH2 . ARG D 2 17  ? -51.241 -13.24  16.6    1   24.15  ? 187 ARG D NH2 1 
ATOM   7036 N  N   . GLU D 2 18  ? -46.578 -8.196  18.998  1   34.51  ? 188 GLU D N   1 
ATOM   7037 C  CA  . GLU D 2 18  ? -45.292 -7.943  18.377  1   36.77  ? 188 GLU D CA  1 
ATOM   7038 C  C   . GLU D 2 18  ? -44.174 -8.144  19.399  1   35.99  ? 188 GLU D C   1 
ATOM   7039 O  O   . GLU D 2 18  ? -43.177 -8.787  19.101  1   35.76  ? 188 GLU D O   1 
ATOM   7040 C  CB  . GLU D 2 18  ? -45.367 -6.539  17.81   1   40.68  ? 188 GLU D CB  1 
ATOM   7041 C  CG  . GLU D 2 18  ? -44.193 -6.008  17.042  1   45.5   ? 188 GLU D CG  1 
ATOM   7042 C  CD  . GLU D 2 18  ? -44.456 -4.55   16.684  1   49.29  ? 188 GLU D CD  1 
ATOM   7043 O  OE1 . GLU D 2 18  ? -45.592 -4.238  16.246  1   44.58  ? 188 GLU D OE1 1 
ATOM   7044 O  OE2 . GLU D 2 18  ? -43.538 -3.718  16.869  1   52.58  ? 188 GLU D OE2 1 
ATOM   7045 N  N   . MET D 2 19  ? -44.379 -7.655  20.625  1   33.38  ? 189 MET D N   1 
ATOM   7046 C  CA  . MET D 2 19  ? -43.347 -7.686  21.648  1   35.96  ? 189 MET D CA  1 
ATOM   7047 C  C   . MET D 2 19  ? -43.107 -9.085  22.212  1   37.26  ? 189 MET D C   1 
ATOM   7048 O  O   . MET D 2 19  ? -41.974 -9.4    22.581  1   37.31  ? 189 MET D O   1 
ATOM   7049 C  CB  . MET D 2 19  ? -43.711 -6.743  22.8    1   37.79  ? 189 MET D CB  1 
ATOM   7050 C  CG  . MET D 2 19  ? -43.677 -5.295  22.401  1   41.42  ? 189 MET D CG  1 
ATOM   7051 S  SD  . MET D 2 19  ? -42.087 -4.708  21.835  1   44.72  ? 189 MET D SD  1 
ATOM   7052 C  CE  . MET D 2 19  ? -41.046 -5.237  23.261  1   52.72  ? 189 MET D CE  1 
ATOM   7053 N  N   . GLU D 2 20  ? -44.157 -9.918  22.279  1   32     ? 190 GLU D N   1 
ATOM   7054 C  CA  . GLU D 2 20  ? -43.999 -11.269 22.799  1   32.3   ? 190 GLU D CA  1 
ATOM   7055 C  C   . GLU D 2 20  ? -43.125 -12.105 21.868  1   32.98  ? 190 GLU D C   1 
ATOM   7056 O  O   . GLU D 2 20  ? -42.444 -13.01  22.334  1   34.82  ? 190 GLU D O   1 
ATOM   7057 C  CB  . GLU D 2 20  ? -45.347 -11.987 23.062  1   31.58  ? 190 GLU D CB  1 
ATOM   7058 C  CG  . GLU D 2 20  ? -46.123 -12.403 21.822  1   29.07  ? 190 GLU D CG  1 
ATOM   7059 C  CD  . GLU D 2 20  ? -47.338 -13.262 22.087  1   29.13  ? 190 GLU D CD  1 
ATOM   7060 O  OE1 . GLU D 2 20  ? -47.562 -13.664 23.252  1   29.43  ? 190 GLU D OE1 1 
ATOM   7061 O  OE2 . GLU D 2 20  ? -48.077 -13.537 21.12   1   28.29  ? 190 GLU D OE2 1 
ATOM   7062 N  N   . VAL D 2 21  ? -43.149 -11.798 20.564  1   32.23  ? 191 VAL D N   1 
ATOM   7063 C  CA  . VAL D 2 21  ? -42.217 -12.389 19.616  1   32.64  ? 191 VAL D CA  1 
ATOM   7064 C  C   . VAL D 2 21  ? -40.786 -11.93  19.903  1   36.26  ? 191 VAL D C   1 
ATOM   7065 O  O   . VAL D 2 21  ? -39.879 -12.747 19.937  1   41     ? 191 VAL D O   1 
ATOM   7066 C  CB  . VAL D 2 21  ? -42.616 -12.081 18.148  1   33.93  ? 191 VAL D CB  1 
ATOM   7067 C  CG1 . VAL D 2 21  ? -41.542 -12.542 17.162  1   33.45  ? 191 VAL D CG1 1 
ATOM   7068 C  CG2 . VAL D 2 21  ? -43.978 -12.694 17.8    1   31.98  ? 191 VAL D CG2 1 
ATOM   7069 N  N   . LYS D 2 22  ? -40.58  -10.627 20.112  1   39.58  ? 192 LYS D N   1 
ATOM   7070 C  CA  . LYS D 2 22  ? -39.267 -10.107 20.463  1   47.35  ? 192 LYS D CA  1 
ATOM   7071 C  C   . LYS D 2 22  ? -38.723 -10.682 21.77   1   41.93  ? 192 LYS D C   1 
ATOM   7072 O  O   . LYS D 2 22  ? -37.544 -11.004 21.853  1   44.46  ? 192 LYS D O   1 
ATOM   7073 C  CB  . LYS D 2 22  ? -39.318 -8.571  20.572  1   62.63  ? 192 LYS D CB  1 
ATOM   7074 C  CG  . LYS D 2 22  ? -37.981 -7.893  20.931  1   74.68  ? 192 LYS D CG  1 
ATOM   7075 C  CD  . LYS D 2 22  ? -38.18  -6.442  21.481  1   84.46  ? 192 LYS D CD  1 
ATOM   7076 C  CE  . LYS D 2 22  ? -37.063 -5.47   21.129  1   88.9   ? 192 LYS D CE  1 
ATOM   7077 N  NZ  . LYS D 2 22  ? -35.74  -5.909  21.647  1   92.4   ? 192 LYS D NZ  1 
ATOM   7078 N  N   . CYS D 2 23  ? -39.586 -10.817 22.785  1   40.36  ? 193 CYS D N   1 
ATOM   7079 C  CA  . CYS D 2 23  ? -39.17  -11.268 24.106  1   39.92  ? 193 CYS D CA  1 
ATOM   7080 C  C   . CYS D 2 23  ? -39.168 -12.786 24.272  1   39.05  ? 193 CYS D C   1 
ATOM   7081 O  O   . CYS D 2 23  ? -39.141 -13.283 25.395  1   41.14  ? 193 CYS D O   1 
ATOM   7082 C  CB  . CYS D 2 23  ? -40.043 -10.624 25.185  1   40.5   ? 193 CYS D CB  1 
ATOM   7083 S  SG  . CYS D 2 23  ? -39.872 -8.83   25.316  1   46.52  ? 193 CYS D SG  1 
ATOM   7084 N  N   . LYS D 2 24  ? -39.203 -13.53  23.166  1   40.5   ? 194 LYS D N   1 
ATOM   7085 C  CA  . LYS D 2 24  ? -39.397 -14.965 23.246  1   38.76  ? 194 LYS D CA  1 
ATOM   7086 C  C   . LYS D 2 24  ? -38.061 -15.65  23.5    1   36.7   ? 194 LYS D C   1 
ATOM   7087 O  O   . LYS D 2 24  ? -37.096 -15.403 22.78   1   33.63  ? 194 LYS D O   1 
ATOM   7088 C  CB  . LYS D 2 24  ? -40.025 -15.525 21.967  1   39.19  ? 194 LYS D CB  1 
ATOM   7089 C  CG  . LYS D 2 24  ? -40.517 -16.953 22.128  1   41.83  ? 194 LYS D CG  1 
ATOM   7090 C  CD  . LYS D 2 24  ? -40.884 -17.593 20.804  1   42.48  ? 194 LYS D CD  1 
ATOM   7091 C  CE  . LYS D 2 24  ? -41.427 -18.994 20.982  1   45.32  ? 194 LYS D CE  1 
ATOM   7092 N  NZ  . LYS D 2 24  ? -41.67  -19.64  19.66   1   47.37  ? 194 LYS D NZ  1 
ATOM   7093 N  N   . PRO D 2 25  ? -37.976 -16.557 24.503  1   38.69  ? 195 PRO D N   1 
ATOM   7094 C  CA  . PRO D 2 25  ? -36.761 -17.352 24.709  1   37.44  ? 195 PRO D CA  1 
ATOM   7095 C  C   . PRO D 2 25  ? -36.504 -18.268 23.521  1   33.79  ? 195 PRO D C   1 
ATOM   7096 O  O   . PRO D 2 25  ? -37.432 -18.547 22.773  1   34.08  ? 195 PRO D O   1 
ATOM   7097 C  CB  . PRO D 2 25  ? -37.056 -18.153 25.98   1   36.53  ? 195 PRO D CB  1 
ATOM   7098 C  CG  . PRO D 2 25  ? -38.304 -17.494 26.604  1   37.91  ? 195 PRO D CG  1 
ATOM   7099 C  CD  . PRO D 2 25  ? -39.045 -16.863 25.476  1   36.48  ? 195 PRO D CD  1 
ATOM   7100 N  N   . LYS D 2 26  ? -35.253 -18.718 23.356  1   35.89  ? 196 LYS D N   1 
ATOM   7101 C  CA  . LYS D 2 26  ? -34.938 -19.766 22.393  1   41.74  ? 196 LYS D CA  1 
ATOM   7102 C  C   . LYS D 2 26  ? -35.629 -21.067 22.788  1   39.12  ? 196 LYS D C   1 
ATOM   7103 O  O   . LYS D 2 26  ? -35.424 -21.551 23.895  1   44.27  ? 196 LYS D O   1 
ATOM   7104 C  CB  . LYS D 2 26  ? -33.428 -20.045 22.296  1   47.13  ? 196 LYS D CB  1 
ATOM   7105 C  CG  . LYS D 2 26  ? -32.578 -18.949 21.649  1   54.83  ? 196 LYS D CG  1 
ATOM   7106 C  CD  . LYS D 2 26  ? -32.978 -18.598 20.231  1   63.67  ? 196 LYS D CD  1 
ATOM   7107 C  CE  . LYS D 2 26  ? -32.047 -17.577 19.605  1   68.32  ? 196 LYS D CE  1 
ATOM   7108 N  NZ  . LYS D 2 26  ? -32.38  -17.344 18.17   1   68.59  ? 196 LYS D NZ  1 
ATOM   7109 N  N   . VAL D 2 27  ? -36.408 -21.639 21.863  1   40.62  ? 197 VAL D N   1 
ATOM   7110 C  CA  . VAL D 2 27  ? -37.17  -22.856 22.105  1   39.86  ? 197 VAL D CA  1 
ATOM   7111 C  C   . VAL D 2 27  ? -36.305 -24.04  22.531  1   37.28  ? 197 VAL D C   1 
ATOM   7112 O  O   . VAL D 2 27  ? -36.713 -24.816 23.39   1   44.83  ? 197 VAL D O   1 
ATOM   7113 C  CB  . VAL D 2 27  ? -38     -23.241 20.857  1   42.22  ? 197 VAL D CB  1 
ATOM   7114 C  CG1 . VAL D 2 27  ? -38.701 -24.586 21.039  1   41.27  ? 197 VAL D CG1 1 
ATOM   7115 C  CG2 . VAL D 2 27  ? -39.006 -22.147 20.517  1   44.36  ? 197 VAL D CG2 1 
ATOM   7116 N  N   . GLY D 2 28  ? -35.114 -24.178 21.941  1   32.17  ? 198 GLY D N   1 
ATOM   7117 C  CA  . GLY D 2 28  ? -34.267 -25.315 22.254  1   33.27  ? 198 GLY D CA  1 
ATOM   7118 C  C   . GLY D 2 28  ? -33.111 -25.071 23.221  1   33.83  ? 198 GLY D C   1 
ATOM   7119 O  O   . GLY D 2 28  ? -32.132 -25.812 23.181  1   34.1   ? 198 GLY D O   1 
ATOM   7120 N  N   . TYR D 2 29  ? -33.221 -24.068 24.106  1   35.82  ? 199 TYR D N   1 
ATOM   7121 C  CA  . TYR D 2 29  ? -32.04  -23.591 24.818  1   34.71  ? 199 TYR D CA  1 
ATOM   7122 C  C   . TYR D 2 29  ? -31.493 -24.645 25.774  1   34.29  ? 199 TYR D C   1 
ATOM   7123 O  O   . TYR D 2 29  ? -30.28  -24.733 25.954  1   30.6   ? 199 TYR D O   1 
ATOM   7124 C  CB  . TYR D 2 29  ? -32.258 -22.228 25.542  1   33.25  ? 199 TYR D CB  1 
ATOM   7125 C  CG  . TYR D 2 29  ? -32.948 -22.227 26.896  1   32.67  ? 199 TYR D CG  1 
ATOM   7126 C  CD1 . TYR D 2 29  ? -32.319 -22.736 28.025  1   33.22  ? 199 TYR D CD1 1 
ATOM   7127 C  CD2 . TYR D 2 29  ? -34.206 -21.663 27.057  1   33.71  ? 199 TYR D CD2 1 
ATOM   7128 C  CE1 . TYR D 2 29  ? -32.938 -22.712 29.273  1   33.5   ? 199 TYR D CE1 1 
ATOM   7129 C  CE2 . TYR D 2 29  ? -34.837 -21.644 28.297  1   34.87  ? 199 TYR D CE2 1 
ATOM   7130 C  CZ  . TYR D 2 29  ? -34.195 -22.157 29.406  1   33.83  ? 199 TYR D CZ  1 
ATOM   7131 O  OH  . TYR D 2 29  ? -34.818 -22.12  30.629  1   34.49  ? 199 TYR D OH  1 
ATOM   7132 N  N   . MET D 2 30  ? -32.379 -25.471 26.341  1   35.81  ? 200 MET D N   1 
ATOM   7133 C  CA  . MET D 2 30  ? -31.989 -26.326 27.448  1   40.33  ? 200 MET D CA  1 
ATOM   7134 C  C   . MET D 2 30  ? -31.029 -27.429 27.003  1   41.21  ? 200 MET D C   1 
ATOM   7135 O  O   . MET D 2 30  ? -30.143 -27.826 27.758  1   38.21  ? 200 MET D O   1 
ATOM   7136 C  CB  . MET D 2 30  ? -33.22  -26.935 28.126  1   42.55  ? 200 MET D CB  1 
ATOM   7137 C  CG  . MET D 2 30  ? -32.895 -27.566 29.457  1   43.51  ? 200 MET D CG  1 
ATOM   7138 S  SD  . MET D 2 30  ? -32.201 -26.364 30.609  1   49.11  ? 200 MET D SD  1 
ATOM   7139 C  CE  . MET D 2 30  ? -33.663 -25.709 31.237  1   53.65  ? 200 MET D CE  1 
ATOM   7140 N  N   . LYS D 2 31  ? -31.195 -27.911 25.768  1   39.35  ? 201 LYS D N   1 
ATOM   7141 C  CA  . LYS D 2 31  ? -30.301 -28.937 25.266  1   41.68  ? 201 LYS D CA  1 
ATOM   7142 C  C   . LYS D 2 31  ? -28.935 -28.347 24.92   1   38.71  ? 201 LYS D C   1 
ATOM   7143 O  O   . LYS D 2 31  ? -27.976 -29.094 24.815  1   39.03  ? 201 LYS D O   1 
ATOM   7144 C  CB  . LYS D 2 31  ? -30.921 -29.758 24.1    1   47.27  ? 201 LYS D CB  1 
ATOM   7145 C  CG  . LYS D 2 31  ? -31.481 -28.983 22.935  1   52.69  ? 201 LYS D CG  1 
ATOM   7146 C  CD  . LYS D 2 31  ? -31.965 -29.926 21.837  1   56.88  ? 201 LYS D CD  1 
ATOM   7147 C  CE  . LYS D 2 31  ? -32.522 -29.204 20.625  1   61.01  ? 201 LYS D CE  1 
ATOM   7148 N  NZ  . LYS D 2 31  ? -33.876 -28.635 20.879  1   61.87  ? 201 LYS D NZ  1 
ATOM   7149 N  N   . LYS D 2 32  ? -28.828 -27.019 24.792  1   37.98  ? 202 LYS D N   1 
ATOM   7150 C  CA  . LYS D 2 32  ? -27.541 -26.363 24.614  1   39.27  ? 202 LYS D CA  1 
ATOM   7151 C  C   . LYS D 2 32  ? -26.869 -25.99  25.936  1   33.95  ? 202 LYS D C   1 
ATOM   7152 O  O   . LYS D 2 32  ? -25.763 -25.464 25.924  1   28.77  ? 202 LYS D O   1 
ATOM   7153 C  CB  . LYS D 2 32  ? -27.694 -25.094 23.76   1   48.59  ? 202 LYS D CB  1 
ATOM   7154 C  CG  . LYS D 2 32  ? -28.259 -25.309 22.355  1   53.8   ? 202 LYS D CG  1 
ATOM   7155 C  CD  . LYS D 2 32  ? -28.497 -23.957 21.647  1   61.66  ? 202 LYS D CD  1 
ATOM   7156 C  CE  . LYS D 2 32  ? -28.951 -24.088 20.206  1   68.13  ? 202 LYS D CE  1 
ATOM   7157 N  NZ  . LYS D 2 32  ? -30.257 -24.787 20.104  1   70.69  ? 202 LYS D NZ  1 
ATOM   7158 N  N   . GLN D 2 33  ? -27.552 -26.238 27.065  1   35.56  ? 203 GLN D N   1 
ATOM   7159 C  CA  . GLN D 2 33  ? -26.99  -26.022 28.391  1   33.17  ? 203 GLN D CA  1 
ATOM   7160 C  C   . GLN D 2 33  ? -26.369 -27.326 28.892  1   33.6   ? 203 GLN D C   1 
ATOM   7161 O  O   . GLN D 2 33  ? -27.081 -28.288 29.185  1   33.11  ? 203 GLN D O   1 
ATOM   7162 C  CB  . GLN D 2 33  ? -28.059 -25.543 29.38   1   30.91  ? 203 GLN D CB  1 
ATOM   7163 C  CG  . GLN D 2 33  ? -28.566 -24.133 29.097  1   33.09  ? 203 GLN D CG  1 
ATOM   7164 C  CD  . GLN D 2 33  ? -27.738 -23.053 29.738  1   30.78  ? 203 GLN D CD  1 
ATOM   7165 O  OE1 . GLN D 2 33  ? -26.778 -23.314 30.467  1   29.77  ? 203 GLN D OE1 1 
ATOM   7166 N  NE2 . GLN D 2 33  ? -28.13  -21.809 29.503  1   28.44  ? 203 GLN D NE2 1 
ATOM   7167 N  N   . PRO D 2 34  ? -25.028 -27.413 29.019  1   32.33  ? 204 PRO D N   1 
ATOM   7168 C  CA  . PRO D 2 34  ? -24.4   -28.675 29.416  1   32.48  ? 204 PRO D CA  1 
ATOM   7169 C  C   . PRO D 2 34  ? -24.785 -29.159 30.813  1   33.21  ? 204 PRO D C   1 
ATOM   7170 O  O   . PRO D 2 34  ? -24.877 -30.363 31.034  1   37.07  ? 204 PRO D O   1 
ATOM   7171 C  CB  . PRO D 2 34  ? -22.892 -28.388 29.309  1   32.57  ? 204 PRO D CB  1 
ATOM   7172 C  CG  . PRO D 2 34  ? -22.778 -27.068 28.527  1   35.33  ? 204 PRO D CG  1 
ATOM   7173 C  CD  . PRO D 2 34  ? -24.061 -26.324 28.799  1   33.27  ? 204 PRO D CD  1 
ATOM   7174 N  N   . ASP D 2 35  ? -25.032 -28.234 31.748  1   32.3   ? 205 ASP D N   1 
ATOM   7175 C  CA  . ASP D 2 35  ? -25.124 -28.608 33.152  1   34.37  ? 205 ASP D CA  1 
ATOM   7176 C  C   . ASP D 2 35  ? -26.496 -28.454 33.807  1   33.9   ? 205 ASP D C   1 
ATOM   7177 O  O   . ASP D 2 35  ? -26.654 -28.8   34.976  1   34.17  ? 205 ASP D O   1 
ATOM   7178 C  CB  . ASP D 2 35  ? -24.097 -27.795 33.951  1   36.72  ? 205 ASP D CB  1 
ATOM   7179 C  CG  . ASP D 2 35  ? -23.666 -28.456 35.231  1   40.36  ? 205 ASP D CG  1 
ATOM   7180 O  OD1 . ASP D 2 35  ? -23.206 -29.62  35.167  1   48.14  ? 205 ASP D OD1 1 
ATOM   7181 O  OD2 . ASP D 2 35  ? -23.782 -27.812 36.303  1   35.9   ? 205 ASP D OD2 1 
ATOM   7182 N  N   . ILE D 2 36  ? -27.485 -27.937 33.066  1   33.57  ? 206 ILE D N   1 
ATOM   7183 C  CA  . ILE D 2 36  ? -28.828 -27.78  33.601  1   33.5   ? 206 ILE D CA  1 
ATOM   7184 C  C   . ILE D 2 36  ? -29.889 -28.353 32.662  1   33.63  ? 206 ILE D C   1 
ATOM   7185 O  O   . ILE D 2 36  ? -29.67  -28.451 31.454  1   34.19  ? 206 ILE D O   1 
ATOM   7186 C  CB  . ILE D 2 36  ? -29.098 -26.297 34.001  1   38.52  ? 206 ILE D CB  1 
ATOM   7187 C  CG1 . ILE D 2 36  ? -29.01  -25.333 32.836  1   41.25  ? 206 ILE D CG1 1 
ATOM   7188 C  CG2 . ILE D 2 36  ? -28.145 -25.845 35.124  1   41.2   ? 206 ILE D CG2 1 
ATOM   7189 C  CD1 . ILE D 2 36  ? -29.272 -23.922 33.236  1   42.74  ? 206 ILE D CD1 1 
ATOM   7190 N  N   . THR D 2 37  ? -31.022 -28.753 33.26   1   30.8   ? 207 THR D N   1 
ATOM   7191 C  CA  . THR D 2 37  ? -32.063 -29.54  32.617  1   29.69  ? 207 THR D CA  1 
ATOM   7192 C  C   . THR D 2 37  ? -33.441 -28.936 32.85   1   31.77  ? 207 THR D C   1 
ATOM   7193 O  O   . THR D 2 37  ? -33.603 -28.092 33.73   1   33.6   ? 207 THR D O   1 
ATOM   7194 C  CB  . THR D 2 37  ? -32.098 -30.98  33.189  1   30.11  ? 207 THR D CB  1 
ATOM   7195 O  OG1 . THR D 2 37  ? -32.368 -30.892 34.597  1   26.73  ? 207 THR D OG1 1 
ATOM   7196 C  CG2 . THR D 2 37  ? -30.806 -31.756 32.918  1   27.77  ? 207 THR D CG2 1 
ATOM   7197 N  N   . ASN D 2 38  ? -34.433 -29.404 32.082  1   33.02  ? 208 ASN D N   1 
ATOM   7198 C  CA  . ASN D 2 38  ? -35.808 -28.967 32.256  1   34.71  ? 208 ASN D CA  1 
ATOM   7199 C  C   . ASN D 2 38  ? -36.284 -29.197 33.688  1   35.23  ? 208 ASN D C   1 
ATOM   7200 O  O   . ASN D 2 38  ? -37.005 -28.37  34.247  1   33.61  ? 208 ASN D O   1 
ATOM   7201 C  CB  . ASN D 2 38  ? -36.744 -29.683 31.285  1   36.16  ? 208 ASN D CB  1 
ATOM   7202 C  CG  . ASN D 2 38  ? -36.533 -29.307 29.83   1   36.39  ? 208 ASN D CG  1 
ATOM   7203 O  OD1 . ASN D 2 38  ? -36.265 -28.152 29.485  1   35.89  ? 208 ASN D OD1 1 
ATOM   7204 N  ND2 . ASN D 2 38  ? -36.646 -30.288 28.948  1   34.64  ? 208 ASN D ND2 1 
ATOM   7205 N  N   . SER D 2 39  ? -35.862 -30.33  34.263  1   34.36  ? 209 SER D N   1 
ATOM   7206 C  CA  . SER D 2 39  ? -36.252 -30.735 35.602  1   33.52  ? 209 SER D CA  1 
ATOM   7207 C  C   . SER D 2 39  ? -35.741 -29.761 36.66   1   32.99  ? 209 SER D C   1 
ATOM   7208 O  O   . SER D 2 39  ? -36.457 -29.43  37.608  1   32.8   ? 209 SER D O   1 
ATOM   7209 C  CB  . SER D 2 39  ? -35.738 -32.146 35.893  1   35.74  ? 209 SER D CB  1 
ATOM   7210 O  OG  . SER D 2 39  ? -35.702 -32.415 37.285  1   35.1   ? 209 SER D OG  1 
ATOM   7211 N  N   . MET D 2 40  ? -34.494 -29.309 36.488  1   31.37  ? 210 MET D N   1 
ATOM   7212 C  CA  . MET D 2 40  ? -33.905 -28.324 37.38   1   29.92  ? 210 MET D CA  1 
ATOM   7213 C  C   . MET D 2 40  ? -34.665 -27.003 37.315  1   28.8   ? 210 MET D C   1 
ATOM   7214 O  O   . MET D 2 40  ? -34.816 -26.328 38.331  1   28.47  ? 210 MET D O   1 
ATOM   7215 C  CB  . MET D 2 40  ? -32.444 -28.071 37.01   1   29.2   ? 210 MET D CB  1 
ATOM   7216 C  CG  . MET D 2 40  ? -31.538 -29.182 37.38   1   29.08  ? 210 MET D CG  1 
ATOM   7217 S  SD  . MET D 2 40  ? -29.859 -28.835 36.908  1   28.28  ? 210 MET D SD  1 
ATOM   7218 C  CE  . MET D 2 40  ? -29.209 -30.49  36.785  1   24.51  ? 210 MET D CE  1 
ATOM   7219 N  N   . ARG D 2 41  ? -35.12  -26.65  36.109  1   26.23  ? 211 ARG D N   1 
ATOM   7220 C  CA  . ARG D 2 41  ? -35.817 -25.398 35.876  1   28.2   ? 211 ARG D CA  1 
ATOM   7221 C  C   . ARG D 2 41  ? -37.205 -25.461 36.5    1   28.48  ? 211 ARG D C   1 
ATOM   7222 O  O   . ARG D 2 41  ? -37.673 -24.469 37.052  1   29.86  ? 211 ARG D O   1 
ATOM   7223 C  CB  . ARG D 2 41  ? -35.908 -25.11  34.367  1   30.21  ? 211 ARG D CB  1 
ATOM   7224 C  CG  . ARG D 2 41  ? -36.775 -23.919 33.997  1   31.12  ? 211 ARG D CG  1 
ATOM   7225 C  CD  . ARG D 2 41  ? -36.987 -23.85  32.507  1   32.27  ? 211 ARG D CD  1 
ATOM   7226 N  NE  . ARG D 2 41  ? -37.912 -22.793 32.119  1   32.12  ? 211 ARG D NE  1 
ATOM   7227 C  CZ  . ARG D 2 41  ? -39.21  -22.794 32.39   1   30.25  ? 211 ARG D CZ  1 
ATOM   7228 N  NH1 . ARG D 2 41  ? -39.821 -23.879 32.837  1   29.49  ? 211 ARG D NH1 1 
ATOM   7229 N  NH2 . ARG D 2 41  ? -39.915 -21.683 32.194  1   29.58  ? 211 ARG D NH2 1 
ATOM   7230 N  N   . ALA D 2 42  ? -37.847 -26.631 36.393  1   29.13  ? 212 ALA D N   1 
ATOM   7231 C  CA  . ALA D 2 42  ? -39.122 -26.888 37.045  1   31.03  ? 212 ALA D CA  1 
ATOM   7232 C  C   . ALA D 2 42  ? -39.043 -26.679 38.559  1   31.54  ? 212 ALA D C   1 
ATOM   7233 O  O   . ALA D 2 42  ? -39.939 -26.078 39.151  1   35.95  ? 212 ALA D O   1 
ATOM   7234 C  CB  . ALA D 2 42  ? -39.602 -28.301 36.735  1   28.98  ? 212 ALA D CB  1 
ATOM   7235 N  N   . ILE D 2 43  ? -37.963 -27.173 39.174  1   29.73  ? 213 ILE D N   1 
ATOM   7236 C  CA  . ILE D 2 43  ? -37.726 -26.975 40.594  1   28.88  ? 213 ILE D CA  1 
ATOM   7237 C  C   . ILE D 2 43  ? -37.59  -25.487 40.919  1   29.01  ? 213 ILE D C   1 
ATOM   7238 O  O   . ILE D 2 43  ? -38.133 -25.008 41.913  1   27.01  ? 213 ILE D O   1 
ATOM   7239 C  CB  . ILE D 2 43  ? -36.479 -27.78  41.029  1   28.97  ? 213 ILE D CB  1 
ATOM   7240 C  CG1 . ILE D 2 43  ? -36.756 -29.306 40.951  1   30.06  ? 213 ILE D CG1 1 
ATOM   7241 C  CG2 . ILE D 2 43  ? -35.997 -27.366 42.415  1   26.89  ? 213 ILE D CG2 1 
ATOM   7242 C  CD1 . ILE D 2 43  ? -35.517 -30.198 41.128  1   29.54  ? 213 ILE D CD1 1 
ATOM   7243 N  N   . LEU D 2 44  ? -36.862 -24.764 40.066  1   28.42  ? 214 LEU D N   1 
ATOM   7244 C  CA  . LEU D 2 44  ? -36.613 -23.351 40.281  1   30.61  ? 214 LEU D CA  1 
ATOM   7245 C  C   . LEU D 2 44  ? -37.911 -22.551 40.235  1   30.67  ? 214 LEU D C   1 
ATOM   7246 O  O   . LEU D 2 44  ? -38.209 -21.775 41.145  1   32.3   ? 214 LEU D O   1 
ATOM   7247 C  CB  . LEU D 2 44  ? -35.634 -22.825 39.218  1   31.35  ? 214 LEU D CB  1 
ATOM   7248 C  CG  . LEU D 2 44  ? -35.301 -21.351 39.293  1   30.75  ? 214 LEU D CG  1 
ATOM   7249 C  CD1 . LEU D 2 44  ? -34.51  -21.055 40.528  1   31.28  ? 214 LEU D CD1 1 
ATOM   7250 C  CD2 . LEU D 2 44  ? -34.536 -20.906 38.053  1   30.92  ? 214 LEU D CD2 1 
ATOM   7251 N  N   . VAL D 2 45  ? -38.688 -22.762 39.171  1   29.56  ? 215 VAL D N   1 
ATOM   7252 C  CA  . VAL D 2 45  ? -39.927 -22.024 38.994  1   29.62  ? 215 VAL D CA  1 
ATOM   7253 C  C   . VAL D 2 45  ? -40.894 -22.346 40.134  1   28.53  ? 215 VAL D C   1 
ATOM   7254 O  O   . VAL D 2 45  ? -41.577 -21.456 40.641  1   28.05  ? 215 VAL D O   1 
ATOM   7255 C  CB  . VAL D 2 45  ? -40.55  -22.28  37.603  1   27.58  ? 215 VAL D CB  1 
ATOM   7256 C  CG1 . VAL D 2 45  ? -41.865 -21.524 37.448  1   28.84  ? 215 VAL D CG1 1 
ATOM   7257 C  CG2 . VAL D 2 45  ? -39.58  -21.902 36.494  1   27.3   ? 215 VAL D CG2 1 
ATOM   7258 N  N   . ASP D 2 46  ? -40.929 -23.617 40.549  1   26.51  ? 216 ASP D N   1 
ATOM   7259 C  CA  . ASP D 2 46  ? -41.796 -24.026 41.642  1   27.96  ? 216 ASP D CA  1 
ATOM   7260 C  C   . ASP D 2 46  ? -41.447 -23.304 42.942  1   27.23  ? 216 ASP D C   1 
ATOM   7261 O  O   . ASP D 2 46  ? -42.338 -22.951 43.715  1   28.87  ? 216 ASP D O   1 
ATOM   7262 C  CB  . ASP D 2 46  ? -41.703 -25.536 41.873  1   25.81  ? 216 ASP D CB  1 
ATOM   7263 C  CG  . ASP D 2 46  ? -42.69  -26.011 42.892  1   26.07  ? 216 ASP D CG  1 
ATOM   7264 O  OD1 . ASP D 2 46  ? -43.854 -26.248 42.52   1   24.46  ? 216 ASP D OD1 1 
ATOM   7265 O  OD2 . ASP D 2 46  ? -42.316 -26.086 44.085  1   28.87  ? 216 ASP D OD2 1 
ATOM   7266 N  N   . TRP D 2 47  ? -40.14  -23.134 43.177  1   25.44  ? 217 TRP D N   1 
ATOM   7267 C  CA  . TRP D 2 47  ? -39.635 -22.365 44.3    1   26.58  ? 217 TRP D CA  1 
ATOM   7268 C  C   . TRP D 2 47  ? -40.015 -20.881 44.196  1   27.3   ? 217 TRP D C   1 
ATOM   7269 O  O   . TRP D 2 47  ? -40.416 -20.273 45.187  1   26.64  ? 217 TRP D O   1 
ATOM   7270 C  CB  . TRP D 2 47  ? -38.112 -22.577 44.402  1   27.04  ? 217 TRP D CB  1 
ATOM   7271 C  CG  . TRP D 2 47  ? -37.435 -21.704 45.403  1   29.73  ? 217 TRP D CG  1 
ATOM   7272 C  CD1 . TRP D 2 47  ? -37.484 -21.82  46.754  1   30.74  ? 217 TRP D CD1 1 
ATOM   7273 C  CD2 . TRP D 2 47  ? -36.646 -20.546 45.129  1   31.43  ? 217 TRP D CD2 1 
ATOM   7274 N  NE1 . TRP D 2 47  ? -36.759 -20.815 47.339  1   31.76  ? 217 TRP D NE1 1 
ATOM   7275 C  CE2 . TRP D 2 47  ? -36.229 -20.02  46.366  1   32.3   ? 217 TRP D CE2 1 
ATOM   7276 C  CE3 . TRP D 2 47  ? -36.225 -19.918 43.955  1   32.27  ? 217 TRP D CE3 1 
ATOM   7277 C  CZ2 . TRP D 2 47  ? -35.417 -18.892 46.467  1   34.09  ? 217 TRP D CZ2 1 
ATOM   7278 C  CZ3 . TRP D 2 47  ? -35.412 -18.801 44.051  1   36.16  ? 217 TRP D CZ3 1 
ATOM   7279 C  CH2 . TRP D 2 47  ? -35.017 -18.297 45.296  1   35.42  ? 217 TRP D CH2 1 
ATOM   7280 N  N   . LEU D 2 48  ? -39.931 -20.313 42.983  1   26.4   ? 218 LEU D N   1 
ATOM   7281 C  CA  . LEU D 2 48  ? -40.327 -18.933 42.762  1   28.1   ? 218 LEU D CA  1 
ATOM   7282 C  C   . LEU D 2 48  ? -41.819 -18.722 43.024  1   30.68  ? 218 LEU D C   1 
ATOM   7283 O  O   . LEU D 2 48  ? -42.218 -17.637 43.448  1   30.27  ? 218 LEU D O   1 
ATOM   7284 C  CB  . LEU D 2 48  ? -39.959 -18.478 41.352  1   28.73  ? 218 LEU D CB  1 
ATOM   7285 C  CG  . LEU D 2 48  ? -38.447 -18.305 41.092  1   32.01  ? 218 LEU D CG  1 
ATOM   7286 C  CD1 . LEU D 2 48  ? -38.172 -17.889 39.663  1   34.3   ? 218 LEU D CD1 1 
ATOM   7287 C  CD2 . LEU D 2 48  ? -37.815 -17.283 42.019  1   32.23  ? 218 LEU D CD2 1 
ATOM   7288 N  N   . VAL D 2 49  ? -42.632 -19.76  42.789  1   30.86  ? 219 VAL D N   1 
ATOM   7289 C  CA  . VAL D 2 49  ? -44.044 -19.71  43.135  1   33.7   ? 219 VAL D CA  1 
ATOM   7290 C  C   . VAL D 2 49  ? -44.22  -19.563 44.646  1   32.74  ? 219 VAL D C   1 
ATOM   7291 O  O   . VAL D 2 49  ? -44.984 -18.711 45.096  1   32.65  ? 219 VAL D O   1 
ATOM   7292 C  CB  . VAL D 2 49  ? -44.805 -20.949 42.587  1   35.73  ? 219 VAL D CB  1 
ATOM   7293 C  CG1 . VAL D 2 49  ? -46.199 -21.1   43.225  1   34.75  ? 219 VAL D CG1 1 
ATOM   7294 C  CG2 . VAL D 2 49  ? -44.902 -20.898 41.061  1   35.16  ? 219 VAL D CG2 1 
ATOM   7295 N  N   . GLU D 2 50  ? -43.508 -20.394 45.419  1   32.77  ? 220 GLU D N   1 
ATOM   7296 C  CA  . GLU D 2 50  ? -43.534 -20.311 46.871  1   33.1   ? 220 GLU D CA  1 
ATOM   7297 C  C   . GLU D 2 50  ? -43.095 -18.938 47.36   1   29.41  ? 220 GLU D C   1 
ATOM   7298 O  O   . GLU D 2 50  ? -43.738 -18.346 48.222  1   30.05  ? 220 GLU D O   1 
ATOM   7299 C  CB  . GLU D 2 50  ? -42.601 -21.345 47.526  1   37.62  ? 220 GLU D CB  1 
ATOM   7300 C  CG  . GLU D 2 50  ? -43.15  -22.747 47.563  1   41.57  ? 220 GLU D CG  1 
ATOM   7301 C  CD  . GLU D 2 50  ? -42.246 -23.749 48.253  1   45.53  ? 220 GLU D CD  1 
ATOM   7302 O  OE1 . GLU D 2 50  ? -41.003 -23.609 48.152  1   42.69  ? 220 GLU D OE1 1 
ATOM   7303 O  OE2 . GLU D 2 50  ? -42.79  -24.704 48.854  1   47.74  ? 220 GLU D OE2 1 
ATOM   7304 N  N   . VAL D 2 51  ? -41.971 -18.464 46.821  1   28.5   ? 221 VAL D N   1 
ATOM   7305 C  CA  . VAL D 2 51  ? -41.47  -17.149 47.171  1   28.7   ? 221 VAL D CA  1 
ATOM   7306 C  C   . VAL D 2 51  ? -42.556 -16.104 46.923  1   27.72  ? 221 VAL D C   1 
ATOM   7307 O  O   . VAL D 2 51  ? -42.822 -15.278 47.79   1   27.51  ? 221 VAL D O   1 
ATOM   7308 C  CB  . VAL D 2 51  ? -40.145 -16.849 46.422  1   26.32  ? 221 VAL D CB  1 
ATOM   7309 C  CG1 . VAL D 2 51  ? -39.757 -15.379 46.531  1   24.78  ? 221 VAL D CG1 1 
ATOM   7310 C  CG2 . VAL D 2 51  ? -39.02  -17.754 46.938  1   25.09  ? 221 VAL D CG2 1 
ATOM   7311 N  N   . GLY D 2 52  ? -43.274 -16.233 45.816  1   27.15  ? 222 GLY D N   1 
ATOM   7312 C  CA  . GLY D 2 52  ? -44.328 -15.264 45.479  1   28.22  ? 222 GLY D CA  1 
ATOM   7313 C  C   . GLY D 2 52  ? -45.468 -15.27  46.472  1   30.32  ? 222 GLY D C   1 
ATOM   7314 O  O   . GLY D 2 52  ? -46.11  -14.223 46.627  1   31.48  ? 222 GLY D O   1 
ATOM   7315 N  N   . GLU D 2 53  ? -45.715 -16.408 47.115  1   31.38  ? 223 GLU D N   1 
ATOM   7316 C  CA  . GLU D 2 53  ? -46.802 -16.514 48.12   1   35.73  ? 223 GLU D CA  1 
ATOM   7317 C  C   . GLU D 2 53  ? -46.28  -16.047 49.483  1   31.78  ? 223 GLU D C   1 
ATOM   7318 O  O   . GLU D 2 53  ? -47.001 -15.322 50.163  1   32.44  ? 223 GLU D O   1 
ATOM   7319 C  CB  . GLU D 2 53  ? -47.347 -17.94  48.155  1   39.6   ? 223 GLU D CB  1 
ATOM   7320 C  CG  . GLU D 2 53  ? -48.099 -18.325 46.886  1   46.34  ? 223 GLU D CG  1 
ATOM   7321 C  CD  . GLU D 2 53  ? -48.972 -17.211 46.343  1   54.06  ? 223 GLU D CD  1 
ATOM   7322 O  OE1 . GLU D 2 53  ? -50.112 -17.07  46.827  1   60.65  ? 223 GLU D OE1 1 
ATOM   7323 O  OE2 . GLU D 2 53  ? -48.516 -16.491 45.431  1   55.99  ? 223 GLU D OE2 1 
ATOM   7324 N  N   . GLU D 2 54  ? -45.061 -16.433 49.839  1   32.28  ? 224 GLU D N   1 
ATOM   7325 C  CA  . GLU D 2 54  ? -44.455 -15.987 51.115  1   34.78  ? 224 GLU D CA  1 
ATOM   7326 C  C   . GLU D 2 54  ? -44.415 -14.454 51.156  1   33.04  ? 224 GLU D C   1 
ATOM   7327 O  O   . GLU D 2 54  ? -44.58  -13.888 52.247  1   30.42  ? 224 GLU D O   1 
ATOM   7328 C  CB  . GLU D 2 54  ? -43.073 -16.621 51.247  1   40.31  ? 224 GLU D CB  1 
ATOM   7329 C  CG  . GLU D 2 54  ? -42.136 -15.889 52.201  1   43.3   ? 224 GLU D CG  1 
ATOM   7330 C  CD  . GLU D 2 54  ? -42.187 -16.349 53.645  1   49.62  ? 224 GLU D CD  1 
ATOM   7331 O  OE1 . GLU D 2 54  ? -43.221 -16.914 54.056  1   61.78  ? 224 GLU D OE1 1 
ATOM   7332 O  OE2 . GLU D 2 54  ? -41.188 -16.137 54.362  1   55.01  ? 224 GLU D OE2 1 
ATOM   7333 N  N   . TYR D 2 55  ? -44.207 -13.815 50.01   1   32.53  ? 225 TYR D N   1 
ATOM   7334 C  CA  . TYR D 2 55  ? -44.095 -12.362 50.007  1   31.79  ? 225 TYR D CA  1 
ATOM   7335 C  C   . TYR D 2 55  ? -45.31  -11.651 49.417  1   31.74  ? 225 TYR D C   1 
ATOM   7336 O  O   . TYR D 2 55  ? -45.301 -10.431 49.282  1   28.94  ? 225 TYR D O   1 
ATOM   7337 C  CB  . TYR D 2 55  ? -42.807 -11.953 49.263  1   31.25  ? 225 TYR D CB  1 
ATOM   7338 C  CG  . TYR D 2 55  ? -41.582 -12.253 50.09   1   31.67  ? 225 TYR D CG  1 
ATOM   7339 C  CD1 . TYR D 2 55  ? -41.193 -11.414 51.121  1   32.9   ? 225 TYR D CD1 1 
ATOM   7340 C  CD2 . TYR D 2 55  ? -40.858 -13.415 49.895  1   34.74  ? 225 TYR D CD2 1 
ATOM   7341 C  CE1 . TYR D 2 55  ? -40.092 -11.712 51.921  1   34.79  ? 225 TYR D CE1 1 
ATOM   7342 C  CE2 . TYR D 2 55  ? -39.76  -13.73  50.691  1   35.07  ? 225 TYR D CE2 1 
ATOM   7343 C  CZ  . TYR D 2 55  ? -39.373 -12.875 51.701  1   34.42  ? 225 TYR D CZ  1 
ATOM   7344 O  OH  . TYR D 2 55  ? -38.267 -13.179 52.463  1   28.12  ? 225 TYR D OH  1 
ATOM   7345 N  N   . LYS D 2 56  ? -46.357 -12.423 49.092  1   35.3   ? 226 LYS D N   1 
ATOM   7346 C  CA  . LYS D 2 56  ? -47.601 -11.887 48.558  1   34.11  ? 226 LYS D CA  1 
ATOM   7347 C  C   . LYS D 2 56  ? -47.322 -10.985 47.363  1   29.05  ? 226 LYS D C   1 
ATOM   7348 O  O   . LYS D 2 56  ? -47.782 -9.847  47.299  1   26.96  ? 226 LYS D O   1 
ATOM   7349 C  CB  . LYS D 2 56  ? -48.381 -11.138 49.649  1   37.65  ? 226 LYS D CB  1 
ATOM   7350 C  CG  . LYS D 2 56  ? -48.608 -11.953 50.924  1   42.66  ? 226 LYS D CG  1 
ATOM   7351 C  CD  . LYS D 2 56  ? -49.321 -13.272 50.664  1   47.25  ? 226 LYS D CD  1 
ATOM   7352 C  CE  . LYS D 2 56  ? -49.576 -14.039 51.931  1   49.01  ? 226 LYS D CE  1 
ATOM   7353 N  NZ  . LYS D 2 56  ? -50.483 -13.283 52.82   1   51.44  ? 226 LYS D NZ  1 
ATOM   7354 N  N   . LEU D 2 57  ? -46.545 -11.519 46.421  1   27.02  ? 227 LEU D N   1 
ATOM   7355 C  CA  . LEU D 2 57  ? -46.209 -10.804 45.206  1   28.06  ? 227 LEU D CA  1 
ATOM   7356 C  C   . LEU D 2 57  ? -47.359 -10.99  44.225  1   29.98  ? 227 LEU D C   1 
ATOM   7357 O  O   . LEU D 2 57  ? -48.129 -11.944 44.351  1   29.21  ? 227 LEU D O   1 
ATOM   7358 C  CB  . LEU D 2 57  ? -44.907 -11.353 44.604  1   27.81  ? 227 LEU D CB  1 
ATOM   7359 C  CG  . LEU D 2 57  ? -43.687 -11.304 45.509  1   29.08  ? 227 LEU D CG  1 
ATOM   7360 C  CD1 . LEU D 2 57  ? -42.477 -11.806 44.79   1   28.82  ? 227 LEU D CD1 1 
ATOM   7361 C  CD2 . LEU D 2 57  ? -43.434 -9.896  46.031  1   27.99  ? 227 LEU D CD2 1 
ATOM   7362 N  N   . GLN D 2 58  ? -47.438 -10.083 43.241  1   31.75  ? 228 GLN D N   1 
ATOM   7363 C  CA  . GLN D 2 58  ? -48.356 -10.229 42.12   1   32.52  ? 228 GLN D CA  1 
ATOM   7364 C  C   . GLN D 2 58  ? -47.988 -11.465 41.305  1   31.11  ? 228 GLN D C   1 
ATOM   7365 O  O   . GLN D 2 58  ? -46.811 -11.805 41.184  1   33.95  ? 228 GLN D O   1 
ATOM   7366 C  CB  . GLN D 2 58  ? -48.299 -8.992  41.213  1   31.63  ? 228 GLN D CB  1 
ATOM   7367 C  CG  . GLN D 2 58  ? -48.725 -7.705  41.899  1   31.72  ? 228 GLN D CG  1 
ATOM   7368 C  CD  . GLN D 2 58  ? -50.178 -7.749  42.277  1   34.81  ? 228 GLN D CD  1 
ATOM   7369 O  OE1 . GLN D 2 58  ? -51.066 -7.846  41.431  1   38.51  ? 228 GLN D OE1 1 
ATOM   7370 N  NE2 . GLN D 2 58  ? -50.459 -7.699  43.561  1   34.44  ? 228 GLN D NE2 1 
ATOM   7371 N  N   . ASN D 2 59  ? -48.997 -12.108 40.717  1   30.81  ? 229 ASN D N   1 
ATOM   7372 C  CA  . ASN D 2 59  ? -48.759 -13.189 39.777  1   31.3   ? 229 ASN D CA  1 
ATOM   7373 C  C   . ASN D 2 59  ? -47.977 -12.712 38.561  1   27.92  ? 229 ASN D C   1 
ATOM   7374 O  O   . ASN D 2 59  ? -47.172 -13.469 38.02   1   28.42  ? 229 ASN D O   1 
ATOM   7375 C  CB  . ASN D 2 59  ? -50.072 -13.824 39.345  1   29.43  ? 229 ASN D CB  1 
ATOM   7376 C  CG  . ASN D 2 59  ? -50.691 -14.63  40.446  1   30.96  ? 229 ASN D CG  1 
ATOM   7377 O  OD1 . ASN D 2 59  ? -50.027 -15.056 41.401  1   33.96  ? 229 ASN D OD1 1 
ATOM   7378 N  ND2 . ASN D 2 59  ? -51.973 -14.884 40.348  1   32.7   ? 229 ASN D ND2 1 
ATOM   7379 N  N   . GLU D 2 60  ? -48.245 -11.47  38.135  1   28.17  ? 230 GLU D N   1 
ATOM   7380 C  CA  . GLU D 2 60  ? -47.542 -10.873 37.007  1   28.57  ? 230 GLU D CA  1 
ATOM   7381 C  C   . GLU D 2 60  ? -46.036 -10.866 37.267  1   31.4   ? 230 GLU D C   1 
ATOM   7382 O  O   . GLU D 2 60  ? -45.249 -11.113 36.362  1   36.29  ? 230 GLU D O   1 
ATOM   7383 C  CB  . GLU D 2 60  ? -48.052 -9.455  36.737  1   28.06  ? 230 GLU D CB  1 
ATOM   7384 C  CG  . GLU D 2 60  ? -47.304 -8.672  35.658  1   31.21  ? 230 GLU D CG  1 
ATOM   7385 C  CD  . GLU D 2 60  ? -47.485 -9.184  34.239  1   30.72  ? 230 GLU D CD  1 
ATOM   7386 O  OE1 . GLU D 2 60  ? -48.27  -10.134 34.042  1   27.62  ? 230 GLU D OE1 1 
ATOM   7387 O  OE2 . GLU D 2 60  ? -46.858 -8.615  33.318  1   31.39  ? 230 GLU D OE2 1 
ATOM   7388 N  N   . THR D 2 61  ? -45.644 -10.6   38.518  1   33.81  ? 231 THR D N   1 
ATOM   7389 C  CA  . THR D 2 61  ? -44.24  -10.584 38.898  1   32.89  ? 231 THR D CA  1 
ATOM   7390 C  C   . THR D 2 61  ? -43.587 -11.941 38.64   1   31.53  ? 231 THR D C   1 
ATOM   7391 O  O   . THR D 2 61  ? -42.495 -11.996 38.086  1   32.17  ? 231 THR D O   1 
ATOM   7392 C  CB  . THR D 2 61  ? -44.084 -10.14  40.358  1   31.24  ? 231 THR D CB  1 
ATOM   7393 O  OG1 . THR D 2 61  ? -44.711 -8.872  40.514  1   31.28  ? 231 THR D OG1 1 
ATOM   7394 C  CG2 . THR D 2 61  ? -42.646 -10.034 40.773  1   32.24  ? 231 THR D CG2 1 
ATOM   7395 N  N   . LEU D 2 62  ? -44.271 -13.019 39.044  1   29.47  ? 232 LEU D N   1 
ATOM   7396 C  CA  . LEU D 2 62  ? -43.802 -14.377 38.813  1   28.52  ? 232 LEU D CA  1 
ATOM   7397 C  C   . LEU D 2 62  ? -43.607 -14.671 37.326  1   28.51  ? 232 LEU D C   1 
ATOM   7398 O  O   . LEU D 2 62  ? -42.575 -15.201 36.928  1   30     ? 232 LEU D O   1 
ATOM   7399 C  CB  . LEU D 2 62  ? -44.794 -15.379 39.427  1   28.94  ? 232 LEU D CB  1 
ATOM   7400 C  CG  . LEU D 2 62  ? -44.604 -16.854 39.087  1   29.7   ? 232 LEU D CG  1 
ATOM   7401 C  CD1 . LEU D 2 62  ? -43.377 -17.403 39.724  1   31.93  ? 232 LEU D CD1 1 
ATOM   7402 C  CD2 . LEU D 2 62  ? -45.79  -17.652 39.515  1   30.58  ? 232 LEU D CD2 1 
ATOM   7403 N  N   . HIS D 2 63  ? -44.6   -14.323 36.508  1   30.92  ? 233 HIS D N   1 
ATOM   7404 C  CA  . HIS D 2 63  ? -44.513 -14.524 35.069  1   32.88  ? 233 HIS D CA  1 
ATOM   7405 C  C   . HIS D 2 63  ? -43.343 -13.76  34.442  1   32.24  ? 233 HIS D C   1 
ATOM   7406 O  O   . HIS D 2 63  ? -42.641 -14.292 33.578  1   35.07  ? 233 HIS D O   1 
ATOM   7407 C  CB  . HIS D 2 63  ? -45.846 -14.131 34.37   1   32.6   ? 233 HIS D CB  1 
ATOM   7408 C  CG  . HIS D 2 63  ? -46.968 -15.118 34.508  1   30.03  ? 233 HIS D CG  1 
ATOM   7409 N  ND1 . HIS D 2 63  ? -47.375 -15.904 33.438  1   26.79  ? 233 HIS D ND1 1 
ATOM   7410 C  CD2 . HIS D 2 63  ? -47.751 -15.4   35.576  1   28.05  ? 233 HIS D CD2 1 
ATOM   7411 C  CE1 . HIS D 2 63  ? -48.378 -16.641 33.895  1   27.18  ? 233 HIS D CE1 1 
ATOM   7412 N  NE2 . HIS D 2 63  ? -48.635 -16.367 35.179  1   27.21  ? 233 HIS D NE2 1 
ATOM   7413 N  N   . LEU D 2 64  ? -43.14  -12.507 34.87   1   30.58  ? 234 LEU D N   1 
ATOM   7414 C  CA  . LEU D 2 64  ? -42.019 -11.717 34.393  1   30.04  ? 234 LEU D CA  1 
ATOM   7415 C  C   . LEU D 2 64  ? -40.688 -12.389 34.73   1   30.74  ? 234 LEU D C   1 
ATOM   7416 O  O   . LEU D 2 64  ? -39.812 -12.516 33.875  1   33.77  ? 234 LEU D O   1 
ATOM   7417 C  CB  . LEU D 2 64  ? -42.073 -10.308 34.992  1   28.59  ? 234 LEU D CB  1 
ATOM   7418 C  CG  . LEU D 2 64  ? -43.157 -9.417  34.437  1   31.77  ? 234 LEU D CG  1 
ATOM   7419 C  CD1 . LEU D 2 64  ? -43.272 -8.12   35.246  1   32.22  ? 234 LEU D CD1 1 
ATOM   7420 C  CD2 . LEU D 2 64  ? -42.903 -9.087  32.947  1   30.37  ? 234 LEU D CD2 1 
ATOM   7421 N  N   . ALA D 2 65  ? -40.542 -12.842 35.98   1   31.84  ? 235 ALA D N   1 
ATOM   7422 C  CA  . ALA D 2 65  ? -39.3   -13.466 36.408  1   33.14  ? 235 ALA D CA  1 
ATOM   7423 C  C   . ALA D 2 65  ? -38.94  -14.668 35.535  1   31.02  ? 235 ALA D C   1 
ATOM   7424 O  O   . ALA D 2 65  ? -37.786 -14.833 35.146  1   31.22  ? 235 ALA D O   1 
ATOM   7425 C  CB  . ALA D 2 65  ? -39.397 -13.868 37.869  1   32.58  ? 235 ALA D CB  1 
ATOM   7426 N  N   . VAL D 2 66  ? -39.942 -15.5   35.226  1   29.26  ? 236 VAL D N   1 
ATOM   7427 C  CA  . VAL D 2 66  ? -39.722 -16.691 34.426  1   29.8   ? 236 VAL D CA  1 
ATOM   7428 C  C   . VAL D 2 66  ? -39.265 -16.282 33.027  1   32.6   ? 236 VAL D C   1 
ATOM   7429 O  O   . VAL D 2 66  ? -38.382 -16.915 32.451  1   32.63  ? 236 VAL D O   1 
ATOM   7430 C  CB  . VAL D 2 66  ? -40.979 -17.587 34.394  1   29.94  ? 236 VAL D CB  1 
ATOM   7431 C  CG1 . VAL D 2 66  ? -40.792 -18.762 33.457  1   28.39  ? 236 VAL D CG1 1 
ATOM   7432 C  CG2 . VAL D 2 66  ? -41.361 -18.067 35.802  1   31.98  ? 236 VAL D CG2 1 
ATOM   7433 N  N   . ASN D 2 67  ? -39.872 -15.219 32.48   1   32.6   ? 237 ASN D N   1 
ATOM   7434 C  CA  . ASN D 2 67  ? -39.468 -14.703 31.184  1   31.98  ? 237 ASN D CA  1 
ATOM   7435 C  C   . ASN D 2 67  ? -37.997 -14.277 31.2    1   32.65  ? 237 ASN D C   1 
ATOM   7436 O  O   . ASN D 2 67  ? -37.248 -14.542 30.259  1   32.12  ? 237 ASN D O   1 
ATOM   7437 C  CB  . ASN D 2 67  ? -40.363 -13.537 30.76   1   30.53  ? 237 ASN D CB  1 
ATOM   7438 C  CG  . ASN D 2 67  ? -39.909 -12.92  29.452  1   32.33  ? 237 ASN D CG  1 
ATOM   7439 O  OD1 . ASN D 2 67  ? -39.221 -11.887 29.41   1   30.44  ? 237 ASN D OD1 1 
ATOM   7440 N  ND2 . ASN D 2 67  ? -40.229 -13.572 28.361  1   31.95  ? 237 ASN D ND2 1 
ATOM   7441 N  N   . TYR D 2 68  ? -37.588 -13.594 32.274  1   32.08  ? 238 TYR D N   1 
ATOM   7442 C  CA  . TYR D 2 68  ? -36.232 -13.078 32.385  1   30.32  ? 238 TYR D CA  1 
ATOM   7443 C  C   . TYR D 2 68  ? -35.218 -14.217 32.446  1   30.71  ? 238 TYR D C   1 
ATOM   7444 O  O   . TYR D 2 68  ? -34.16  -14.152 31.808  1   29.58  ? 238 TYR D O   1 
ATOM   7445 C  CB  . TYR D 2 68  ? -36.078 -12.17  33.619  1   29.35  ? 238 TYR D CB  1 
ATOM   7446 C  CG  . TYR D 2 68  ? -36.96  -10.933 33.656  1   30.75  ? 238 TYR D CG  1 
ATOM   7447 C  CD1 . TYR D 2 68  ? -37.673 -10.522 32.537  1   31.23  ? 238 TYR D CD1 1 
ATOM   7448 C  CD2 . TYR D 2 68  ? -37.1   -10.192 34.82   1   31.43  ? 238 TYR D CD2 1 
ATOM   7449 C  CE1 . TYR D 2 68  ? -38.488 -9.397  32.571  1   31.65  ? 238 TYR D CE1 1 
ATOM   7450 C  CE2 . TYR D 2 68  ? -37.922 -9.075  34.87   1   34.14  ? 238 TYR D CE2 1 
ATOM   7451 C  CZ  . TYR D 2 68  ? -38.616 -8.678  33.743  1   34.14  ? 238 TYR D CZ  1 
ATOM   7452 O  OH  . TYR D 2 68  ? -39.416 -7.562  33.8    1   34.2   ? 238 TYR D OH  1 
ATOM   7453 N  N   . ILE D 2 69  ? -35.56  -15.256 33.223  1   29.43  ? 239 ILE D N   1 
ATOM   7454 C  CA  . ILE D 2 69  ? -34.708 -16.428 33.367  1   29.85  ? 239 ILE D CA  1 
ATOM   7455 C  C   . ILE D 2 69  ? -34.508 -17.12  32.021  1   30.47  ? 239 ILE D C   1 
ATOM   7456 O  O   . ILE D 2 69  ? -33.383 -17.396 31.613  1   29.9   ? 239 ILE D O   1 
ATOM   7457 C  CB  . ILE D 2 69  ? -35.302 -17.399 34.414  1   29.92  ? 239 ILE D CB  1 
ATOM   7458 C  CG1 . ILE D 2 69  ? -35.297 -16.758 35.846  1   27.69  ? 239 ILE D CG1 1 
ATOM   7459 C  CG2 . ILE D 2 69  ? -34.576 -18.739 34.4    1   28.56  ? 239 ILE D CG2 1 
ATOM   7460 C  CD1 . ILE D 2 69  ? -36.21  -17.436 36.819  1   26.8   ? 239 ILE D CD1 1 
ATOM   7461 N  N   . ASP D 2 70  ? -35.621 -17.391 31.332  1   31.47  ? 240 ASP D N   1 
ATOM   7462 C  CA  . ASP D 2 70  ? -35.577 -18.141 30.091  1   30.85  ? 240 ASP D CA  1 
ATOM   7463 C  C   . ASP D 2 70  ? -34.798 -17.398 29.01   1   28.78  ? 240 ASP D C   1 
ATOM   7464 O  O   . ASP D 2 70  ? -34.097 -18.035 28.229  1   28.44  ? 240 ASP D O   1 
ATOM   7465 C  CB  . ASP D 2 70  ? -36.997 -18.516 29.619  1   30.01  ? 240 ASP D CB  1 
ATOM   7466 C  CG  . ASP D 2 70  ? -37.655 -19.63  30.407  1   30.72  ? 240 ASP D CG  1 
ATOM   7467 O  OD1 . ASP D 2 70  ? -36.921 -20.454 30.998  1   32.44  ? 240 ASP D OD1 1 
ATOM   7468 O  OD2 . ASP D 2 70  ? -38.905 -19.662 30.457  1   30.39  ? 240 ASP D OD2 1 
ATOM   7469 N  N   . ARG D 2 71  ? -34.909 -16.066 28.966  1   28.73  ? 241 ARG D N   1 
ATOM   7470 C  CA  . ARG D 2 71  ? -34.129 -15.282 28.018  1   29.33  ? 241 ARG D CA  1 
ATOM   7471 C  C   . ARG D 2 71  ? -32.651 -15.286 28.399  1   28.13  ? 241 ARG D C   1 
ATOM   7472 O  O   . ARG D 2 71  ? -31.787 -15.381 27.531  1   27.52  ? 241 ARG D O   1 
ATOM   7473 C  CB  . ARG D 2 71  ? -34.648 -13.851 27.907  1   30.8   ? 241 ARG D CB  1 
ATOM   7474 C  CG  . ARG D 2 71  ? -35.93  -13.729 27.073  1   34.67  ? 241 ARG D CG  1 
ATOM   7475 C  CD  . ARG D 2 71  ? -36.777 -12.545 27.505  1   35.68  ? 241 ARG D CD  1 
ATOM   7476 N  NE  . ARG D 2 71  ? -36.209 -11.291 27.035  1   35.23  ? 241 ARG D NE  1 
ATOM   7477 C  CZ  . ARG D 2 71  ? -36.467 -10.101 27.558  1   34.27  ? 241 ARG D CZ  1 
ATOM   7478 N  NH1 . ARG D 2 71  ? -37.397 -9.931  28.488  1   34.09  ? 241 ARG D NH1 1 
ATOM   7479 N  NH2 . ARG D 2 71  ? -35.772 -9.053  27.134  1   34.23  ? 241 ARG D NH2 1 
ATOM   7480 N  N   . PHE D 2 72  ? -32.374 -15.192 29.704  1   27.83  ? 242 PHE D N   1 
ATOM   7481 C  CA  . PHE D 2 72  ? -31.007 -15.173 30.192  1   27.21  ? 242 PHE D CA  1 
ATOM   7482 C  C   . PHE D 2 72  ? -30.314 -16.492 29.853  1   28.31  ? 242 PHE D C   1 
ATOM   7483 O  O   . PHE D 2 72  ? -29.209 -16.494 29.312  1   29.92  ? 242 PHE D O   1 
ATOM   7484 C  CB  . PHE D 2 72  ? -30.976 -14.92  31.701  1   27.55  ? 242 PHE D CB  1 
ATOM   7485 C  CG  . PHE D 2 72  ? -29.583 -14.752 32.257  1   28.51  ? 242 PHE D CG  1 
ATOM   7486 C  CD1 . PHE D 2 72  ? -28.951 -13.518 32.234  1   29.69  ? 242 PHE D CD1 1 
ATOM   7487 C  CD2 . PHE D 2 72  ? -28.885 -15.838 32.757  1   30.76  ? 242 PHE D CD2 1 
ATOM   7488 C  CE1 . PHE D 2 72  ? -27.668 -13.38  32.724  1   30.15  ? 242 PHE D CE1 1 
ATOM   7489 C  CE2 . PHE D 2 72  ? -27.603 -15.695 33.252  1   27.19  ? 242 PHE D CE2 1 
ATOM   7490 C  CZ  . PHE D 2 72  ? -27.002 -14.478 33.229  1   29.85  ? 242 PHE D CZ  1 
ATOM   7491 N  N   . LEU D 2 73  ? -30.978 -17.612 30.16   1   27.69  ? 243 LEU D N   1 
ATOM   7492 C  CA  . LEU D 2 73  ? -30.442 -18.932 29.86   1   31.01  ? 243 LEU D CA  1 
ATOM   7493 C  C   . LEU D 2 73  ? -30.419 -19.259 28.364  1   28.45  ? 243 LEU D C   1 
ATOM   7494 O  O   . LEU D 2 73  ? -29.824 -20.245 27.96   1   30.87  ? 243 LEU D O   1 
ATOM   7495 C  CB  . LEU D 2 73  ? -31.26  -20.006 30.604  1   33.4   ? 243 LEU D CB  1 
ATOM   7496 C  CG  . LEU D 2 73  ? -31.219 -19.931 32.115  1   33.93  ? 243 LEU D CG  1 
ATOM   7497 C  CD1 . LEU D 2 73  ? -32.044 -21.02  32.712  1   36.14  ? 243 LEU D CD1 1 
ATOM   7498 C  CD2 . LEU D 2 73  ? -29.795 -20.015 32.623  1   36.95  ? 243 LEU D CD2 1 
ATOM   7499 N  N   . SER D 2 74  ? -31.077 -18.447 27.539  1   28.79  ? 244 SER D N   1 
ATOM   7500 C  CA  . SER D 2 74  ? -30.951 -18.555 26.092  1   30.92  ? 244 SER D CA  1 
ATOM   7501 C  C   . SER D 2 74  ? -29.634 -17.994 25.545  1   29.1   ? 244 SER D C   1 
ATOM   7502 O  O   . SER D 2 74  ? -29.226 -18.336 24.437  1   25.83  ? 244 SER D O   1 
ATOM   7503 C  CB  . SER D 2 74  ? -32.127 -17.85  25.415  1   33.12  ? 244 SER D CB  1 
ATOM   7504 O  OG  . SER D 2 74  ? -33.38  -18.422 25.771  1   31.29  ? 244 SER D OG  1 
ATOM   7505 N  N   . SER D 2 75  ? -28.973 -17.129 26.323  1   30.5   ? 245 SER D N   1 
ATOM   7506 C  CA  . SER D 2 75  ? -27.734 -16.478 25.916  1   34.85  ? 245 SER D CA  1 
ATOM   7507 C  C   . SER D 2 75  ? -26.506 -16.851 26.761  1   31.42  ? 245 SER D C   1 
ATOM   7508 O  O   . SER D 2 75  ? -25.382 -16.666 26.31   1   31.96  ? 245 SER D O   1 
ATOM   7509 C  CB  . SER D 2 75  ? -27.896 -14.948 25.966  1   40.9   ? 245 SER D CB  1 
ATOM   7510 O  OG  . SER D 2 75  ? -28.835 -14.388 25.05   1   42.48  ? 245 SER D OG  1 
ATOM   7511 N  N   . MET D 2 76  ? -26.715 -17.357 27.988  1   31.09  ? 246 MET D N   1 
ATOM   7512 C  CA  . MET D 2 76  ? -25.626 -17.605 28.922  1   30.33  ? 246 MET D CA  1 
ATOM   7513 C  C   . MET D 2 76  ? -25.669 -19.049 29.428  1   30.93  ? 246 MET D C   1 
ATOM   7514 O  O   . MET D 2 76  ? -26.7   -19.497 29.938  1   31.08  ? 246 MET D O   1 
ATOM   7515 C  CB  . MET D 2 76  ? -25.742 -16.661 30.14   1   30.62  ? 246 MET D CB  1 
ATOM   7516 C  CG  . MET D 2 76  ? -25.86  -15.202 29.773  1   31.97  ? 246 MET D CG  1 
ATOM   7517 S  SD  . MET D 2 76  ? -24.307 -14.479 29.194  1   31.95  ? 246 MET D SD  1 
ATOM   7518 C  CE  . MET D 2 76  ? -23.387 -14.405 30.746  1   30.4   ? 246 MET D CE  1 
ATOM   7519 N  N   . SER D 2 77  ? -24.538 -19.764 29.333  1   26.84  ? 247 SER D N   1 
ATOM   7520 C  CA  . SER D 2 77  ? -24.381 -21.035 30.023  1   26.14  ? 247 SER D CA  1 
ATOM   7521 C  C   . SER D 2 77  ? -24.272 -20.778 31.523  1   26.66  ? 247 SER D C   1 
ATOM   7522 O  O   . SER D 2 77  ? -23.553 -19.872 31.935  1   29.12  ? 247 SER D O   1 
ATOM   7523 C  CB  . SER D 2 77  ? -23.133 -21.783 29.554  1   24.97  ? 247 SER D CB  1 
ATOM   7524 O  OG  . SER D 2 77  ? -23.144 -22.012 28.157  1   25.41  ? 247 SER D OG  1 
ATOM   7525 N  N   . VAL D 2 78  ? -24.97  -21.589 32.323  1   27.03  ? 248 VAL D N   1 
ATOM   7526 C  CA  . VAL D 2 78  ? -24.969 -21.453 33.769  1   29.27  ? 248 VAL D CA  1 
ATOM   7527 C  C   . VAL D 2 78  ? -24.793 -22.819 34.419  1   27.91  ? 248 VAL D C   1 
ATOM   7528 O  O   . VAL D 2 78  ? -25.449 -23.773 34.021  1   29.86  ? 248 VAL D O   1 
ATOM   7529 C  CB  . VAL D 2 78  ? -26.276 -20.787 34.252  1   30.12  ? 248 VAL D CB  1 
ATOM   7530 C  CG1 . VAL D 2 78  ? -26.382 -20.798 35.794  1   29.76  ? 248 VAL D CG1 1 
ATOM   7531 C  CG2 . VAL D 2 78  ? -26.41  -19.376 33.671  1   27.26  ? 248 VAL D CG2 1 
ATOM   7532 N  N   . LEU D 2 79  ? -23.899 -22.903 35.41   1   27.81  ? 249 LEU D N   1 
ATOM   7533 C  CA  . LEU D 2 79  ? -23.707 -24.131 36.158  1   28.12  ? 249 LEU D CA  1 
ATOM   7534 C  C   . LEU D 2 79  ? -24.861 -24.316 37.143  1   28.66  ? 249 LEU D C   1 
ATOM   7535 O  O   . LEU D 2 79  ? -25.432 -23.342 37.635  1   29.39  ? 249 LEU D O   1 
ATOM   7536 C  CB  . LEU D 2 79  ? -22.359 -24.121 36.891  1   27.74  ? 249 LEU D CB  1 
ATOM   7537 C  CG  . LEU D 2 79  ? -21.093 -24.17  36.013  1   29.36  ? 249 LEU D CG  1 
ATOM   7538 C  CD1 . LEU D 2 79  ? -19.877 -24.629 36.85   1   26.68  ? 249 LEU D CD1 1 
ATOM   7539 C  CD2 . LEU D 2 79  ? -21.25  -25.082 34.744  1   26.74  ? 249 LEU D CD2 1 
ATOM   7540 N  N   . ARG D 2 80  ? -25.189 -25.58  37.434  1   28.23  ? 250 ARG D N   1 
ATOM   7541 C  CA  . ARG D 2 80  ? -26.289 -25.916 38.327  1   30.12  ? 250 ARG D CA  1 
ATOM   7542 C  C   . ARG D 2 80  ? -26.249 -25.136 39.638  1   28.47  ? 250 ARG D C   1 
ATOM   7543 O  O   . ARG D 2 80  ? -27.285 -24.685 40.121  1   30.36  ? 250 ARG D O   1 
ATOM   7544 C  CB  . ARG D 2 80  ? -26.259 -27.405 38.643  1   30.03  ? 250 ARG D CB  1 
ATOM   7545 C  CG  . ARG D 2 80  ? -27.344 -27.873 39.576  1   33.61  ? 250 ARG D CG  1 
ATOM   7546 C  CD  . ARG D 2 80  ? -27.198 -29.366 39.804  1   35.39  ? 250 ARG D CD  1 
ATOM   7547 N  NE  . ARG D 2 80  ? -25.941 -29.682 40.472  1   34.89  ? 250 ARG D NE  1 
ATOM   7548 C  CZ  . ARG D 2 80  ? -25.342 -30.865 40.447  1   35.11  ? 250 ARG D CZ  1 
ATOM   7549 N  NH1 . ARG D 2 80  ? -25.797 -31.86  39.699  1   36.66  ? 250 ARG D NH1 1 
ATOM   7550 N  NH2 . ARG D 2 80  ? -24.238 -31.041 41.165  1   35.92  ? 250 ARG D NH2 1 
ATOM   7551 N  N   . GLY D 2 81  ? -25.045 -24.971 40.196  1   26.9   ? 251 GLY D N   1 
ATOM   7552 C  CA  . GLY D 2 81  ? -24.864 -24.253 41.448  1   25.53  ? 251 GLY D CA  1 
ATOM   7553 C  C   . GLY D 2 81  ? -25.268 -22.782 41.399  1   26.16  ? 251 GLY D C   1 
ATOM   7554 O  O   . GLY D 2 81  ? -25.509 -22.181 42.439  1   25.31  ? 251 GLY D O   1 
ATOM   7555 N  N   . LYS D 2 82  ? -25.341 -22.21  40.19   1   26.15  ? 252 LYS D N   1 
ATOM   7556 C  CA  . LYS D 2 82  ? -25.664 -20.804 40.03   1   26.29  ? 252 LYS D CA  1 
ATOM   7557 C  C   . LYS D 2 82  ? -27.056 -20.568 39.459  1   26.48  ? 252 LYS D C   1 
ATOM   7558 O  O   . LYS D 2 82  ? -27.452 -19.421 39.29   1   26.93  ? 252 LYS D O   1 
ATOM   7559 C  CB  . LYS D 2 82  ? -24.618 -20.128 39.126  1   26.36  ? 252 LYS D CB  1 
ATOM   7560 C  CG  . LYS D 2 82  ? -23.249 -20.025 39.755  1   28.34  ? 252 LYS D CG  1 
ATOM   7561 C  CD  . LYS D 2 82  ? -23.261 -19.164 41.001  1   31.41  ? 252 LYS D CD  1 
ATOM   7562 C  CE  . LYS D 2 82  ? -21.905 -18.753 41.474  1   31.73  ? 252 LYS D CE  1 
ATOM   7563 N  NZ  . LYS D 2 82  ? -21.139 -19.927 41.884  1   35.93  ? 252 LYS D NZ  1 
ATOM   7564 N  N   . LEU D 2 83  ? -27.785 -21.645 39.149  1   26.4   ? 253 LEU D N   1 
ATOM   7565 C  CA  . LEU D 2 83  ? -29.118 -21.502 38.588  1   26.89  ? 253 LEU D CA  1 
ATOM   7566 C  C   . LEU D 2 83  ? -30.048 -20.714 39.509  1   26.83  ? 253 LEU D C   1 
ATOM   7567 O  O   . LEU D 2 83  ? -30.819 -19.876 39.048  1   30.18  ? 253 LEU D O   1 
ATOM   7568 C  CB  . LEU D 2 83  ? -29.719 -22.885 38.291  1   27.8   ? 253 LEU D CB  1 
ATOM   7569 C  CG  . LEU D 2 83  ? -31.132 -22.868 37.725  1   28.36  ? 253 LEU D CG  1 
ATOM   7570 C  CD1 . LEU D 2 83  ? -31.174 -22.15  36.392  1   26.16  ? 253 LEU D CD1 1 
ATOM   7571 C  CD2 . LEU D 2 83  ? -31.66  -24.268 37.614  1   30.11  ? 253 LEU D CD2 1 
ATOM   7572 N  N   . GLN D 2 84  ? -29.971 -20.975 40.818  1   27.63  ? 254 GLN D N   1 
ATOM   7573 C  CA  . GLN D 2 84  ? -30.827 -20.281 41.765  1   29.89  ? 254 GLN D CA  1 
ATOM   7574 C  C   . GLN D 2 84  ? -30.453 -18.803 41.888  1   30.03  ? 254 GLN D C   1 
ATOM   7575 O  O   . GLN D 2 84  ? -31.31  -17.974 42.198  1   32.15  ? 254 GLN D O   1 
ATOM   7576 C  CB  . GLN D 2 84  ? -30.785 -20.962 43.149  1   31.18  ? 254 GLN D CB  1 
ATOM   7577 C  CG  . GLN D 2 84  ? -31.888 -20.474 44.095  1   31.46  ? 254 GLN D CG  1 
ATOM   7578 C  CD  . GLN D 2 84  ? -31.898 -21.212 45.403  1   32.08  ? 254 GLN D CD  1 
ATOM   7579 O  OE1 . GLN D 2 84  ? -30.955 -21.937 45.761  1   34.33  ? 254 GLN D OE1 1 
ATOM   7580 N  NE2 . GLN D 2 84  ? -32.967 -21.031 46.149  1   31.59  ? 254 GLN D NE2 1 
ATOM   7581 N  N   . LEU D 2 85  ? -29.176 -18.478 41.651  1   25.75  ? 255 LEU D N   1 
ATOM   7582 C  CA  . LEU D 2 85  ? -28.726 -17.099 41.713  1   26.41  ? 255 LEU D CA  1 
ATOM   7583 C  C   . LEU D 2 85  ? -29.361 -16.288 40.585  1   28.85  ? 255 LEU D C   1 
ATOM   7584 O  O   . LEU D 2 85  ? -29.806 -15.167 40.808  1   25.65  ? 255 LEU D O   1 
ATOM   7585 C  CB  . LEU D 2 85  ? -27.199 -17.017 41.656  1   26.96  ? 255 LEU D CB  1 
ATOM   7586 C  CG  . LEU D 2 85  ? -26.63  -15.613 41.688  1   29.44  ? 255 LEU D CG  1 
ATOM   7587 C  CD1 . LEU D 2 85  ? -27.068 -14.864 42.949  1   30.94  ? 255 LEU D CD1 1 
ATOM   7588 C  CD2 . LEU D 2 85  ? -25.134 -15.626 41.625  1   29.47  ? 255 LEU D CD2 1 
ATOM   7589 N  N   . VAL D 2 86  ? -29.41  -16.875 39.38   1   30.6   ? 256 VAL D N   1 
ATOM   7590 C  CA  . VAL D 2 86  ? -30.088 -16.266 38.249  1   30.01  ? 256 VAL D CA  1 
ATOM   7591 C  C   . VAL D 2 86  ? -31.558 -16.018 38.587  1   29.65  ? 256 VAL D C   1 
ATOM   7592 O  O   . VAL D 2 86  ? -32.057 -14.906 38.43   1   27.91  ? 256 VAL D O   1 
ATOM   7593 C  CB  . VAL D 2 86  ? -29.942 -17.129 36.998  1   29.48  ? 256 VAL D CB  1 
ATOM   7594 C  CG1 . VAL D 2 86  ? -30.807 -16.592 35.867  1   30.82  ? 256 VAL D CG1 1 
ATOM   7595 C  CG2 . VAL D 2 86  ? -28.479 -17.221 36.569  1   32.79  ? 256 VAL D CG2 1 
ATOM   7596 N  N   . GLY D 2 87  ? -32.224 -17.063 39.085  1   29.53  ? 257 GLY D N   1 
ATOM   7597 C  CA  . GLY D 2 87  ? -33.618 -16.981 39.489  1   28.94  ? 257 GLY D CA  1 
ATOM   7598 C  C   . GLY D 2 87  ? -33.909 -15.924 40.552  1   28.69  ? 257 GLY D C   1 
ATOM   7599 O  O   . GLY D 2 87  ? -34.912 -15.22  40.461  1   27.79  ? 257 GLY D O   1 
ATOM   7600 N  N   . THR D 2 88  ? -33.042 -15.839 41.569  1   27.36  ? 258 THR D N   1 
ATOM   7601 C  CA  . THR D 2 88  ? -33.223 -14.858 42.628  1   28.53  ? 258 THR D CA  1 
ATOM   7602 C  C   . THR D 2 88  ? -33.122 -13.441 42.067  1   28.89  ? 258 THR D C   1 
ATOM   7603 O  O   . THR D 2 88  ? -33.932 -12.578 42.406  1   28.69  ? 258 THR D O   1 
ATOM   7604 C  CB  . THR D 2 88  ? -32.226 -15.058 43.765  1   28.26  ? 258 THR D CB  1 
ATOM   7605 O  OG1 . THR D 2 88  ? -32.22  -16.418 44.158  1   32.53  ? 258 THR D OG1 1 
ATOM   7606 C  CG2 . THR D 2 88  ? -32.571 -14.249 44.941  1   28.67  ? 258 THR D CG2 1 
ATOM   7607 N  N   . ALA D 2 89  ? -32.132 -13.219 41.189  1   27.92  ? 259 ALA D N   1 
ATOM   7608 C  CA  . ALA D 2 89  ? -31.911 -11.908 40.603  1   27.33  ? 259 ALA D CA  1 
ATOM   7609 C  C   . ALA D 2 89  ? -33.058 -11.529 39.674  1   28.64  ? 259 ALA D C   1 
ATOM   7610 O  O   . ALA D 2 89  ? -33.472 -10.371 39.64   1   30.4   ? 259 ALA D O   1 
ATOM   7611 C  CB  . ALA D 2 89  ? -30.604 -11.875 39.869  1   26.73  ? 259 ALA D CB  1 
ATOM   7612 N  N   . ALA D 2 90  ? -33.573 -12.518 38.94   1   27.29  ? 260 ALA D N   1 
ATOM   7613 C  CA  . ALA D 2 90  ? -34.713 -12.297 38.064  1   26.94  ? 260 ALA D CA  1 
ATOM   7614 C  C   . ALA D 2 90  ? -35.963 -11.898 38.841  1   25.4   ? 260 ALA D C   1 
ATOM   7615 O  O   . ALA D 2 90  ? -36.676 -10.977 38.446  1   24.65  ? 260 ALA D O   1 
ATOM   7616 C  CB  . ALA D 2 90  ? -34.983 -13.526 37.246  1   27     ? 260 ALA D CB  1 
ATOM   7617 N  N   . MET D 2 91  ? -36.2   -12.568 39.972  1   28.56  ? 261 MET D N   1 
ATOM   7618 C  CA  . MET D 2 91  ? -37.359 -12.277 40.804  1   28.69  ? 261 MET D CA  1 
ATOM   7619 C  C   . MET D 2 91  ? -37.234 -10.88  41.419  1   28.9   ? 261 MET D C   1 
ATOM   7620 O  O   . MET D 2 91  ? -38.229 -10.165 41.557  1   30.25  ? 261 MET D O   1 
ATOM   7621 C  CB  . MET D 2 91  ? -37.52  -13.338 41.896  1   28.94  ? 261 MET D CB  1 
ATOM   7622 C  CG  . MET D 2 91  ? -38.883 -13.309 42.561  1   32.39  ? 261 MET D CG  1 
ATOM   7623 S  SD  . MET D 2 91  ? -40.214 -13.73  41.418  1   35.29  ? 261 MET D SD  1 
ATOM   7624 C  CE  . MET D 2 91  ? -41.169 -14.776 42.427  1   37.81  ? 261 MET D CE  1 
ATOM   7625 N  N   . LEU D 2 92  ? -35.998 -10.482 41.751  1   27.6   ? 262 LEU D N   1 
ATOM   7626 C  CA  . LEU D 2 92  ? -35.734 -9.155  42.289  1   28.58  ? 262 LEU D CA  1 
ATOM   7627 C  C   . LEU D 2 92  ? -36.053 -8.081  41.253  1   27.72  ? 262 LEU D C   1 
ATOM   7628 O  O   . LEU D 2 92  ? -36.705 -7.086  41.558  1   26.79  ? 262 LEU D O   1 
ATOM   7629 C  CB  . LEU D 2 92  ? -34.277 -9.074  42.754  1   27.1   ? 262 LEU D CB  1 
ATOM   7630 C  CG  . LEU D 2 92  ? -33.731 -7.718  43.173  1   26.66  ? 262 LEU D CG  1 
ATOM   7631 C  CD1 . LEU D 2 92  ? -34.454 -7.141  44.397  1   25.28  ? 262 LEU D CD1 1 
ATOM   7632 C  CD2 . LEU D 2 92  ? -32.243 -7.846  43.442  1   26.18  ? 262 LEU D CD2 1 
ATOM   7633 N  N   . LEU D 2 93  ? -35.601 -8.313  40.02   1   28.1   ? 263 LEU D N   1 
ATOM   7634 C  CA  . LEU D 2 93  ? -35.819 -7.38   38.932  1   27.63  ? 263 LEU D CA  1 
ATOM   7635 C  C   . LEU D 2 93  ? -37.3   -7.256  38.597  1   27.41  ? 263 LEU D C   1 
ATOM   7636 O  O   . LEU D 2 93  ? -37.788 -6.141  38.421  1   28.87  ? 263 LEU D O   1 
ATOM   7637 C  CB  . LEU D 2 93  ? -35.017 -7.813  37.71   1   30.18  ? 263 LEU D CB  1 
ATOM   7638 C  CG  . LEU D 2 93  ? -33.536 -7.469  37.761  1   31.76  ? 263 LEU D CG  1 
ATOM   7639 C  CD1 . LEU D 2 93  ? -32.774 -8.152  36.634  1   33.47  ? 263 LEU D CD1 1 
ATOM   7640 C  CD2 . LEU D 2 93  ? -33.325 -5.966  37.681  1   31.17  ? 263 LEU D CD2 1 
ATOM   7641 N  N   . ALA D 2 94  ? -38.002 -8.397  38.55   1   27.44  ? 264 ALA D N   1 
ATOM   7642 C  CA  . ALA D 2 94  ? -39.434 -8.417  38.295  1   27.41  ? 264 ALA D CA  1 
ATOM   7643 C  C   . ALA D 2 94  ? -40.187 -7.656  39.378  1   27.53  ? 264 ALA D C   1 
ATOM   7644 O  O   . ALA D 2 94  ? -41.12  -6.919  39.08   1   30.34  ? 264 ALA D O   1 
ATOM   7645 C  CB  . ALA D 2 94  ? -39.946 -9.839  38.213  1   28.33  ? 264 ALA D CB  1 
ATOM   7646 N  N   . SER D 2 95  ? -39.768 -7.85   40.629  1   27.98  ? 265 SER D N   1 
ATOM   7647 C  CA  . SER D 2 95  ? -40.337 -7.13   41.756  1   30.06  ? 265 SER D CA  1 
ATOM   7648 C  C   . SER D 2 95  ? -40.124 -5.624  41.628  1   28.97  ? 265 SER D C   1 
ATOM   7649 O  O   . SER D 2 95  ? -41.059 -4.846  41.785  1   30.31  ? 265 SER D O   1 
ATOM   7650 C  CB  . SER D 2 95  ? -39.756 -7.638  43.077  1   29.66  ? 265 SER D CB  1 
ATOM   7651 O  OG  . SER D 2 95  ? -40.071 -9.013  43.27   1   27.87  ? 265 SER D OG  1 
ATOM   7652 N  N   . LYS D 2 96  ? -38.889 -5.209  41.336  1   29.46  ? 266 LYS D N   1 
ATOM   7653 C  CA  . LYS D 2 96  ? -38.62  -3.789  41.183  1   29.02  ? 266 LYS D CA  1 
ATOM   7654 C  C   . LYS D 2 96  ? -39.42  -3.187  40.032  1   26.57  ? 266 LYS D C   1 
ATOM   7655 O  O   . LYS D 2 96  ? -39.852 -2.042  40.12   1   25.84  ? 266 LYS D O   1 
ATOM   7656 C  CB  . LYS D 2 96  ? -37.131 -3.527  40.963  1   27.84  ? 266 LYS D CB  1 
ATOM   7657 C  CG  . LYS D 2 96  ? -36.276 -3.722  42.201  1   24.34  ? 266 LYS D CG  1 
ATOM   7658 C  CD  . LYS D 2 96  ? -34.873 -3.305  41.937  1   24.21  ? 266 LYS D CD  1 
ATOM   7659 C  CE  . LYS D 2 96  ? -33.978 -3.569  43.108  1   24.87  ? 266 LYS D CE  1 
ATOM   7660 N  NZ  . LYS D 2 96  ? -32.58  -3.222  42.791  1   23.89  ? 266 LYS D NZ  1 
ATOM   7661 N  N   . PHE D 2 97  ? -39.619 -3.966  38.961  1   27.06  ? 267 PHE D N   1 
ATOM   7662 C  CA  . PHE D 2 97  ? -40.376 -3.496  37.81   1   26.81  ? 267 PHE D CA  1 
ATOM   7663 C  C   . PHE D 2 97  ? -41.856 -3.356  38.135  1   25.73  ? 267 PHE D C   1 
ATOM   7664 O  O   . PHE D 2 97  ? -42.441 -2.309  37.889  1   28.3   ? 267 PHE D O   1 
ATOM   7665 C  CB  . PHE D 2 97  ? -40.225 -4.453  36.625  1   28.46  ? 267 PHE D CB  1 
ATOM   7666 C  CG  . PHE D 2 97  ? -40.922 -3.989  35.364  1   30.14  ? 267 PHE D CG  1 
ATOM   7667 C  CD1 . PHE D 2 97  ? -40.307 -3.109  34.498  1   30.48  ? 267 PHE D CD1 1 
ATOM   7668 C  CD2 . PHE D 2 97  ? -42.189 -4.451  35.04   1   29.89  ? 267 PHE D CD2 1 
ATOM   7669 C  CE1 . PHE D 2 97  ? -40.948 -2.687  33.327  1   31.74  ? 267 PHE D CE1 1 
ATOM   7670 C  CE2 . PHE D 2 97  ? -42.831 -4.025  33.879  1   30.94  ? 267 PHE D CE2 1 
ATOM   7671 C  CZ  . PHE D 2 97  ? -42.204 -3.145  33.027  1   32.86  ? 267 PHE D CZ  1 
ATOM   7672 N  N   . GLU D 2 98  ? -42.438 -4.421  38.701  1   27.65  ? 268 GLU D N   1 
ATOM   7673 C  CA  . GLU D 2 98  ? -43.881 -4.6    38.736  1   27.96  ? 268 GLU D CA  1 
ATOM   7674 C  C   . GLU D 2 98  ? -44.557 -4.258  40.061  1   29.42  ? 268 GLU D C   1 
ATOM   7675 O  O   . GLU D 2 98  ? -45.724 -3.882  40.056  1   30.07  ? 268 GLU D O   1 
ATOM   7676 C  CB  . GLU D 2 98  ? -44.214 -6.057  38.375  1   27.05  ? 268 GLU D CB  1 
ATOM   7677 C  CG  . GLU D 2 98  ? -45.692 -6.303  38.075  1   26.89  ? 268 GLU D CG  1 
ATOM   7678 C  CD  . GLU D 2 98  ? -46.244 -5.497  36.907  1   27.97  ? 268 GLU D CD  1 
ATOM   7679 O  OE1 . GLU D 2 98  ? -45.456 -5.131  36      1   24.58  ? 268 GLU D OE1 1 
ATOM   7680 O  OE2 . GLU D 2 98  ? -47.466 -5.207  36.915  1   26.26  ? 268 GLU D OE2 1 
ATOM   7681 N  N   . GLU D 2 99  ? -43.842 -4.399  41.189  1   32.34  ? 269 GLU D N   1 
ATOM   7682 C  CA  . GLU D 2 99  ? -44.459 -4.257  42.503  1   31.73  ? 269 GLU D CA  1 
ATOM   7683 C  C   . GLU D 2 99  ? -44.449 -2.81   42.98   1   30.42  ? 269 GLU D C   1 
ATOM   7684 O  O   . GLU D 2 99  ? -43.486 -2.075  42.754  1   31.69  ? 269 GLU D O   1 
ATOM   7685 C  CB  . GLU D 2 99  ? -43.752 -5.106  43.566  1   29.15  ? 269 GLU D CB  1 
ATOM   7686 C  CG  . GLU D 2 99  ? -43.841 -6.615  43.354  1   29.46  ? 269 GLU D CG  1 
ATOM   7687 C  CD  . GLU D 2 99  ? -45.185 -7.266  43.605  1   28.4   ? 269 GLU D CD  1 
ATOM   7688 O  OE1 . GLU D 2 99  ? -45.88  -6.854  44.557  1   29.49  ? 269 GLU D OE1 1 
ATOM   7689 O  OE2 . GLU D 2 99  ? -45.529 -8.22   42.874  1   28.33  ? 269 GLU D OE2 1 
ATOM   7690 N  N   . ILE D 2 100 ? -45.525 -2.439  43.683  1   29.91  ? 270 ILE D N   1 
ATOM   7691 C  CA  . ILE D 2 100 ? -45.601 -1.171  44.383  1   32.05  ? 270 ILE D CA  1 
ATOM   7692 C  C   . ILE D 2 100 ? -44.58  -1.142  45.522  1   35.22  ? 270 ILE D C   1 
ATOM   7693 O  O   . ILE D 2 100 ? -43.862 -0.161  45.689  1   35.81  ? 270 ILE D O   1 
ATOM   7694 C  CB  . ILE D 2 100 ? -47.029 -0.927  44.9    1   31.67  ? 270 ILE D CB  1 
ATOM   7695 C  CG1 . ILE D 2 100 ? -48.077 -0.929  43.775  1   30.04  ? 270 ILE D CG1 1 
ATOM   7696 C  CG2 . ILE D 2 100 ? -47.109 0.377   45.698  1   31.85  ? 270 ILE D CG2 1 
ATOM   7697 C  CD1 . ILE D 2 100 ? -49.562 -0.78   44.325  1   27.69  ? 270 ILE D CD1 1 
ATOM   7698 N  N   . TYR D 2 101 ? -44.554 -2.218  46.321  1   37.23  ? 271 TYR D N   1 
ATOM   7699 C  CA  . TYR D 2 101 ? -43.685 -2.317  47.486  1   33.56  ? 271 TYR D CA  1 
ATOM   7700 C  C   . TYR D 2 101 ? -42.82  -3.568  47.355  1   32.33  ? 271 TYR D C   1 
ATOM   7701 O  O   . TYR D 2 101 ? -43.102 -4.58   47.988  1   33.31  ? 271 TYR D O   1 
ATOM   7702 C  CB  . TYR D 2 101 ? -44.507 -2.389  48.802  1   34     ? 271 TYR D CB  1 
ATOM   7703 C  CG  . TYR D 2 101 ? -45.37  -1.175  49.07   1   34.44  ? 271 TYR D CG  1 
ATOM   7704 C  CD1 . TYR D 2 101 ? -44.803 0.04    49.431  1   35.54  ? 271 TYR D CD1 1 
ATOM   7705 C  CD2 . TYR D 2 101 ? -46.754 -1.234  48.936  1   36.03  ? 271 TYR D CD2 1 
ATOM   7706 C  CE1 . TYR D 2 101 ? -45.59  1.169   49.648  1   38.13  ? 271 TYR D CE1 1 
ATOM   7707 C  CE2 . TYR D 2 101 ? -47.556 -0.115  49.165  1   36.12  ? 271 TYR D CE2 1 
ATOM   7708 C  CZ  . TYR D 2 101 ? -46.97  1.086   49.518  1   39.23  ? 271 TYR D CZ  1 
ATOM   7709 O  OH  . TYR D 2 101 ? -47.757 2.194   49.73   1   44.32  ? 271 TYR D OH  1 
ATOM   7710 N  N   . PRO D 2 102 ? -41.737 -3.553  46.544  1   30.5   ? 272 PRO D N   1 
ATOM   7711 C  CA  . PRO D 2 102 ? -40.93  -4.758  46.338  1   27.54  ? 272 PRO D CA  1 
ATOM   7712 C  C   . PRO D 2 102 ? -40.245 -5.169  47.636  1   27.39  ? 272 PRO D C   1 
ATOM   7713 O  O   . PRO D 2 102 ? -39.958 -4.323  48.472  1   26.84  ? 272 PRO D O   1 
ATOM   7714 C  CB  . PRO D 2 102 ? -39.92  -4.334  45.28   1   28.1   ? 272 PRO D CB  1 
ATOM   7715 C  CG  . PRO D 2 102 ? -39.861 -2.818  45.393  1   29.11  ? 272 PRO D CG  1 
ATOM   7716 C  CD  . PRO D 2 102 ? -41.222 -2.378  45.817  1   28.13  ? 272 PRO D CD  1 
ATOM   7717 N  N   . PRO D 2 103 ? -39.958 -6.466  47.865  1   28.01  ? 273 PRO D N   1 
ATOM   7718 C  CA  . PRO D 2 103 ? -39.111 -6.842  48.99   1   28.7   ? 273 PRO D CA  1 
ATOM   7719 C  C   . PRO D 2 103 ? -37.704 -6.282  48.778  1   29.86  ? 273 PRO D C   1 
ATOM   7720 O  O   . PRO D 2 103 ? -37.255 -6.084  47.643  1   28.81  ? 273 PRO D O   1 
ATOM   7721 C  CB  . PRO D 2 103 ? -39.166 -8.381  48.997  1   29.85  ? 273 PRO D CB  1 
ATOM   7722 C  CG  . PRO D 2 103 ? -40.273 -8.764  48.035  1   30.71  ? 273 PRO D CG  1 
ATOM   7723 C  CD  . PRO D 2 103 ? -40.395 -7.624  47.064  1   29.64  ? 273 PRO D CD  1 
ATOM   7724 N  N   . GLU D 2 104 ? -37.03  -6.019  49.897  1   30.5   ? 274 GLU D N   1 
ATOM   7725 C  CA  . GLU D 2 104 ? -35.659 -5.553  49.89   1   32.75  ? 274 GLU D CA  1 
ATOM   7726 C  C   . GLU D 2 104 ? -34.731 -6.662  49.422  1   29.89  ? 274 GLU D C   1 
ATOM   7727 O  O   . GLU D 2 104 ? -35.069 -7.844  49.487  1   30.4   ? 274 GLU D O   1 
ATOM   7728 C  CB  . GLU D 2 104 ? -35.266 -5.074  51.281  1   38.51  ? 274 GLU D CB  1 
ATOM   7729 C  CG  . GLU D 2 104 ? -35.989 -3.789  51.635  1   42.95  ? 274 GLU D CG  1 
ATOM   7730 C  CD  . GLU D 2 104 ? -35.854 -3.332  53.064  1   52.58  ? 274 GLU D CD  1 
ATOM   7731 O  OE1 . GLU D 2 104 ? -35.32  -4.093  53.902  1   57.28  ? 274 GLU D OE1 1 
ATOM   7732 O  OE2 . GLU D 2 104 ? -36.282 -2.191  53.343  1   63.72  ? 274 GLU D OE2 1 
ATOM   7733 N  N   . VAL D 2 105 ? -33.554 -6.251  48.951  1   26.59  ? 275 VAL D N   1 
ATOM   7734 C  CA  . VAL D 2 105 ? -32.546 -7.206  48.531  1   29.18  ? 275 VAL D CA  1 
ATOM   7735 C  C   . VAL D 2 105 ? -32.273 -8.24   49.628  1   28.91  ? 275 VAL D C   1 
ATOM   7736 O  O   . VAL D 2 105 ? -32.154 -9.428  49.343  1   29.93  ? 275 VAL D O   1 
ATOM   7737 C  CB  . VAL D 2 105 ? -31.267 -6.463  48.075  1   28.47  ? 275 VAL D CB  1 
ATOM   7738 C  CG1 . VAL D 2 105 ? -30.142 -7.435  47.772  1   29.55  ? 275 VAL D CG1 1 
ATOM   7739 C  CG2 . VAL D 2 105 ? -31.557 -5.586  46.861  1   29.77  ? 275 VAL D CG2 1 
ATOM   7740 N  N   . ALA D 2 106 ? -32.195 -7.783  50.885  1   28.56  ? 276 ALA D N   1 
ATOM   7741 C  CA  . ALA D 2 106 ? -31.89  -8.669  51.996  1   31.34  ? 276 ALA D CA  1 
ATOM   7742 C  C   . ALA D 2 106 ? -32.84  -9.862  52.074  1   32.05  ? 276 ALA D C   1 
ATOM   7743 O  O   . ALA D 2 106 ? -32.418 -10.966 52.41   1   31.26  ? 276 ALA D O   1 
ATOM   7744 C  CB  . ALA D 2 106 ? -31.906 -7.907  53.317  1   29.64  ? 276 ALA D CB  1 
ATOM   7745 N  N   A GLU D 2 107 ? -34.121 -9.614  51.774  0.5 32.41  ? 277 GLU D N   1 
ATOM   7746 N  N   B GLU D 2 107 ? -34.122 -9.648  51.766  0.5 30.17  ? 277 GLU D N   1 
ATOM   7747 C  CA  A GLU D 2 107 ? -35.136 -10.65  51.803  0.5 33.63  ? 277 GLU D CA  1 
ATOM   7748 C  CA  B GLU D 2 107 ? -35.089 -10.729 51.83   0.5 29.74  ? 277 GLU D CA  1 
ATOM   7749 C  C   A GLU D 2 107 ? -34.879 -11.688 50.709  0.5 34.2   ? 277 GLU D C   1 
ATOM   7750 C  C   B GLU D 2 107 ? -34.85  -11.727 50.7    0.5 31.87  ? 277 GLU D C   1 
ATOM   7751 O  O   A GLU D 2 107 ? -35.075 -12.882 50.927  0.5 35.8   ? 277 GLU D O   1 
ATOM   7752 O  O   B GLU D 2 107 ? -35.04  -12.928 50.876  0.5 33.02  ? 277 GLU D O   1 
ATOM   7753 C  CB  A GLU D 2 107 ? -36.54  -10.017 51.676  0.5 36.4   ? 277 GLU D CB  1 
ATOM   7754 C  CB  B GLU D 2 107 ? -36.525 -10.187 51.806  0.5 29.4   ? 277 GLU D CB  1 
ATOM   7755 C  CG  A GLU D 2 107 ? -36.972 -9.18   52.881  0.5 37.99  ? 277 GLU D CG  1 
ATOM   7756 C  CG  B GLU D 2 107 ? -36.978 -9.632  53.149  0.5 28.21  ? 277 GLU D CG  1 
ATOM   7757 C  CD  A GLU D 2 107 ? -38.171 -8.26   52.661  0.5 40.82  ? 277 GLU D CD  1 
ATOM   7758 C  CD  B GLU D 2 107 ? -36.896 -10.615 54.299  0.5 27.42  ? 277 GLU D CD  1 
ATOM   7759 O  OE1 A GLU D 2 107 ? -39.295 -8.764  52.441  0.5 45.03  ? 277 GLU D OE1 1 
ATOM   7760 O  OE1 B GLU D 2 107 ? -37.545 -11.683 54.231  0.5 26.43  ? 277 GLU D OE1 1 
ATOM   7761 O  OE2 A GLU D 2 107 ? -37.986 -7.022  52.697  0.5 38.98  ? 277 GLU D OE2 1 
ATOM   7762 O  OE2 B GLU D 2 107 ? -36.169 -10.317 55.271  0.5 28.17  ? 277 GLU D OE2 1 
ATOM   7763 N  N   . PHE D 2 108 ? -34.414 -11.228 49.54   1   34.25  ? 278 PHE D N   1 
ATOM   7764 C  CA  . PHE D 2 108 ? -34.05  -12.111 48.443  1   30.49  ? 278 PHE D CA  1 
ATOM   7765 C  C   . PHE D 2 108 ? -32.802 -12.937 48.761  1   31.95  ? 278 PHE D C   1 
ATOM   7766 O  O   . PHE D 2 108 ? -32.637 -14.047 48.234  1   31.82  ? 278 PHE D O   1 
ATOM   7767 C  CB  . PHE D 2 108 ? -33.859 -11.316 47.127  1   30.48  ? 278 PHE D CB  1 
ATOM   7768 C  CG  . PHE D 2 108 ? -35.167 -10.912 46.502  1   29.49  ? 278 PHE D CG  1 
ATOM   7769 C  CD1 . PHE D 2 108 ? -35.934 -11.835 45.802  1   27.71  ? 278 PHE D CD1 1 
ATOM   7770 C  CD2 . PHE D 2 108 ? -35.673 -9.628  46.671  1   27.34  ? 278 PHE D CD2 1 
ATOM   7771 C  CE1 . PHE D 2 108 ? -37.153 -11.475 45.255  1   25.83  ? 278 PHE D CE1 1 
ATOM   7772 C  CE2 . PHE D 2 108 ? -36.903 -9.272  46.117  1   27.85  ? 278 PHE D CE2 1 
ATOM   7773 C  CZ  . PHE D 2 108 ? -37.628 -10.194 45.405  1   25.9   ? 278 PHE D CZ  1 
ATOM   7774 N  N   . VAL D 2 109 ? -31.912 -12.387 49.599  1   30.66  ? 279 VAL D N   1 
ATOM   7775 C  CA  . VAL D 2 109 ? -30.767 -13.146 50.077  1   32.97  ? 279 VAL D CA  1 
ATOM   7776 C  C   . VAL D 2 109 ? -31.217 -14.213 51.074  1   33.48  ? 279 VAL D C   1 
ATOM   7777 O  O   . VAL D 2 109 ? -30.71  -15.336 51.057  1   35.75  ? 279 VAL D O   1 
ATOM   7778 C  CB  . VAL D 2 109 ? -29.676 -12.261 50.718  1   33.06  ? 279 VAL D CB  1 
ATOM   7779 C  CG1 . VAL D 2 109 ? -28.577 -13.118 51.363  1   31.82  ? 279 VAL D CG1 1 
ATOM   7780 C  CG2 . VAL D 2 109 ? -29.084 -11.304 49.712  1   34.08  ? 279 VAL D CG2 1 
ATOM   7781 N  N   . TYR D 2 110 ? -32.142 -13.817 51.96   1   35.7   ? 280 TYR D N   1 
ATOM   7782 C  CA  . TYR D 2 110 ? -32.664 -14.685 53      1   35.07  ? 280 TYR D CA  1 
ATOM   7783 C  C   . TYR D 2 110 ? -33.327 -15.939 52.428  1   34.81  ? 280 TYR D C   1 
ATOM   7784 O  O   . TYR D 2 110 ? -33.059 -17.038 52.9    1   32.34  ? 280 TYR D O   1 
ATOM   7785 C  CB  . TYR D 2 110 ? -33.65  -13.904 53.897  1   38.02  ? 280 TYR D CB  1 
ATOM   7786 C  CG  . TYR D 2 110 ? -34.276 -14.738 55.004  1   47.64  ? 280 TYR D CG  1 
ATOM   7787 C  CD1 . TYR D 2 110 ? -33.561 -15.06  56.153  1   51.61  ? 280 TYR D CD1 1 
ATOM   7788 C  CD2 . TYR D 2 110 ? -35.577 -15.22  54.893  1   49.54  ? 280 TYR D CD2 1 
ATOM   7789 C  CE1 . TYR D 2 110 ? -34.133 -15.823 57.171  1   54.41  ? 280 TYR D CE1 1 
ATOM   7790 C  CE2 . TYR D 2 110 ? -36.155 -15.989 55.898  1   50.12  ? 280 TYR D CE2 1 
ATOM   7791 C  CZ  . TYR D 2 110 ? -35.43  -16.289 57.037  1   53.68  ? 280 TYR D CZ  1 
ATOM   7792 O  OH  . TYR D 2 110 ? -36.006 -17.052 58.026  1   52.46  ? 280 TYR D OH  1 
ATOM   7793 N  N   . ILE D 2 111 ? -34.168 -15.789 51.395  1   36.43  ? 281 ILE D N   1 
ATOM   7794 C  CA  . ILE D 2 111 ? -34.875 -16.939 50.846  1   39.82  ? 281 ILE D CA  1 
ATOM   7795 C  C   . ILE D 2 111 ? -34.005 -17.98  50.14   1   40.58  ? 281 ILE D C   1 
ATOM   7796 O  O   . ILE D 2 111 ? -34.478 -19.087 49.905  1   38.69  ? 281 ILE D O   1 
ATOM   7797 C  CB  . ILE D 2 111 ? -36     -16.553 49.87   1   39.58  ? 281 ILE D CB  1 
ATOM   7798 C  CG1 . ILE D 2 111 ? -35.528 -15.468 48.905  1   39.07  ? 281 ILE D CG1 1 
ATOM   7799 C  CG2 . ILE D 2 111 ? -37.257 -16.171 50.626  1   41.34  ? 281 ILE D CG2 1 
ATOM   7800 C  CD1 . ILE D 2 111 ? -36.059 -15.58  47.555  1   41.05  ? 281 ILE D CD1 1 
ATOM   7801 N  N   . THR D 2 112 ? -32.757 -17.635 49.789  1   43.04  ? 282 THR D N   1 
ATOM   7802 C  CA  . THR D 2 112 ? -31.834 -18.615 49.235  1   43.27  ? 282 THR D CA  1 
ATOM   7803 C  C   . THR D 2 112 ? -31.068 -19.377 50.313  1   45.98  ? 282 THR D C   1 
ATOM   7804 O  O   . THR D 2 112 ? -30.079 -20.03  49.993  1   46.61  ? 282 THR D O   1 
ATOM   7805 C  CB  . THR D 2 112 ? -30.815 -17.979 48.274  1   44.52  ? 282 THR D CB  1 
ATOM   7806 O  OG1 . THR D 2 112 ? -29.914 -17.162 49.021  1   48.52  ? 282 THR D OG1 1 
ATOM   7807 C  CG2 . THR D 2 112 ? -31.463 -17.167 47.184  1   42.64  ? 282 THR D CG2 1 
ATOM   7808 N  N   . ASP D 2 113 ? -31.531 -19.282 51.573  1   52.87  ? 283 ASP D N   1 
ATOM   7809 C  CA  . ASP D 2 113 ? -30.9   -19.925 52.721  1   59.3   ? 283 ASP D CA  1 
ATOM   7810 C  C   . ASP D 2 113 ? -29.422 -19.556 52.864  1   61.33  ? 283 ASP D C   1 
ATOM   7811 O  O   . ASP D 2 113 ? -28.619 -20.381 53.292  1   58.53  ? 283 ASP D O   1 
ATOM   7812 C  CB  . ASP D 2 113 ? -31.051 -21.474 52.655  1   62.75  ? 283 ASP D CB  1 
ATOM   7813 C  CG  . ASP D 2 113 ? -32.285 -22.028 53.318  1   65.61  ? 283 ASP D CG  1 
ATOM   7814 O  OD1 . ASP D 2 113 ? -33.388 -21.515 53.035  1   68.28  ? 283 ASP D OD1 1 
ATOM   7815 O  OD2 . ASP D 2 113 ? -32.146 -22.981 54.12   1   61.91  ? 283 ASP D OD2 1 
ATOM   7816 N  N   . ASP D 2 114 ? -29.079 -18.312 52.505  1   63.62  ? 284 ASP D N   1 
ATOM   7817 C  CA  . ASP D 2 114 ? -27.694 -17.869 52.409  1   64.3   ? 284 ASP D CA  1 
ATOM   7818 C  C   . ASP D 2 114 ? -26.781 -18.814 51.613  1   57.38  ? 284 ASP D C   1 
ATOM   7819 O  O   . ASP D 2 114 ? -25.6   -18.963 51.924  1   51.6   ? 284 ASP D O   1 
ATOM   7820 C  CB  . ASP D 2 114 ? -27.13  -17.616 53.82   1   69.01  ? 284 ASP D CB  1 
ATOM   7821 C  CG  . ASP D 2 114 ? -27.943 -16.629 54.641  1   67.11  ? 284 ASP D CG  1 
ATOM   7822 O  OD1 . ASP D 2 114 ? -27.982 -15.424 54.27   1   60.71  ? 284 ASP D OD1 1 
ATOM   7823 O  OD2 . ASP D 2 114 ? -28.524 -17.049 55.654  1   73.45  ? 284 ASP D OD2 1 
ATOM   7824 N  N   . THR D 2 115 ? -27.326 -19.428 50.553  1   52.42  ? 285 THR D N   1 
ATOM   7825 C  CA  . THR D 2 115 ? -26.506 -20.076 49.544  1   49.82  ? 285 THR D CA  1 
ATOM   7826 C  C   . THR D 2 115 ? -25.597 -19.021 48.915  1   43.83  ? 285 THR D C   1 
ATOM   7827 O  O   . THR D 2 115 ? -24.43  -19.288 48.647  1   41.97  ? 285 THR D O   1 
ATOM   7828 C  CB  . THR D 2 115 ? -27.377 -20.782 48.48   1   50.89  ? 285 THR D CB  1 
ATOM   7829 O  OG1 . THR D 2 115 ? -28.37  -21.57  49.128  1   48.44  ? 285 THR D OG1 1 
ATOM   7830 C  CG2 . THR D 2 115 ? -26.568 -21.675 47.556  1   49.46  ? 285 THR D CG2 1 
ATOM   7831 N  N   . TYR D 2 116 ? -26.152 -17.821 48.7    1   39.14  ? 286 TYR D N   1 
ATOM   7832 C  CA  . TYR D 2 116 ? -25.432 -16.725 48.076  1   37.54  ? 286 TYR D CA  1 
ATOM   7833 C  C   . TYR D 2 116 ? -25.278 -15.541 49.027  1   36.43  ? 286 TYR D C   1 
ATOM   7834 O  O   . TYR D 2 116 ? -26.009 -15.427 50.008  1   38.49  ? 286 TYR D O   1 
ATOM   7835 C  CB  . TYR D 2 116 ? -26.168 -16.296 46.806  1   36     ? 286 TYR D CB  1 
ATOM   7836 C  CG  . TYR D 2 116 ? -26.472 -17.457 45.891  1   33.34  ? 286 TYR D CG  1 
ATOM   7837 C  CD1 . TYR D 2 116 ? -25.453 -18.157 45.264  1   32.9   ? 286 TYR D CD1 1 
ATOM   7838 C  CD2 . TYR D 2 116 ? -27.776 -17.877 45.679  1   33.51  ? 286 TYR D CD2 1 
ATOM   7839 C  CE1 . TYR D 2 116 ? -25.724 -19.24  44.436  1   33.22  ? 286 TYR D CE1 1 
ATOM   7840 C  CE2 . TYR D 2 116 ? -28.061 -18.958 44.852  1   33.29  ? 286 TYR D CE2 1 
ATOM   7841 C  CZ  . TYR D 2 116 ? -27.031 -19.638 44.23   1   33.79  ? 286 TYR D CZ  1 
ATOM   7842 O  OH  . TYR D 2 116 ? -27.305 -20.705 43.404  1   34.33  ? 286 TYR D OH  1 
ATOM   7843 N  N   . THR D 2 117 ? -24.311 -14.675 48.713  1   35.86  ? 287 THR D N   1 
ATOM   7844 C  CA  . THR D 2 117 ? -24.139 -13.408 49.4    1   35.61  ? 287 THR D CA  1 
ATOM   7845 C  C   . THR D 2 117 ? -24.979 -12.311 48.755  1   36.23  ? 287 THR D C   1 
ATOM   7846 O  O   . THR D 2 117 ? -25.388 -12.42  47.595  1   32.41  ? 287 THR D O   1 
ATOM   7847 C  CB  . THR D 2 117 ? -22.674 -12.984 49.382  1   34.61  ? 287 THR D CB  1 
ATOM   7848 O  OG1 . THR D 2 117 ? -22.292 -12.771 48.033  1   31.31  ? 287 THR D OG1 1 
ATOM   7849 C  CG2 . THR D 2 117 ? -21.759 -14.018 50.02   1   33.36  ? 287 THR D CG2 1 
ATOM   7850 N  N   . LYS D 2 118 ? -25.208 -11.238 49.52   1   36.86  ? 288 LYS D N   1 
ATOM   7851 C  CA  . LYS D 2 118 ? -25.907 -10.075 49.001  1   37.98  ? 288 LYS D CA  1 
ATOM   7852 C  C   . LYS D 2 118 ? -25.204 -9.526  47.76   1   37.3   ? 288 LYS D C   1 
ATOM   7853 O  O   . LYS D 2 118 ? -25.853 -9.159  46.779  1   36.8   ? 288 LYS D O   1 
ATOM   7854 C  CB  . LYS D 2 118 ? -26.032 -8.99   50.076  1   39.33  ? 288 LYS D CB  1 
ATOM   7855 C  CG  . LYS D 2 118 ? -26.934 -7.857  49.645  1   41.96  ? 288 LYS D CG  1 
ATOM   7856 C  CD  . LYS D 2 118 ? -26.824 -6.611  50.507  1   47.47  ? 288 LYS D CD  1 
ATOM   7857 C  CE  . LYS D 2 118 ? -27.683 -6.629  51.725  1   46.01  ? 288 LYS D CE  1 
ATOM   7858 N  NZ  . LYS D 2 118 ? -27.566 -5.353  52.462  1   44.4   ? 288 LYS D NZ  1 
ATOM   7859 N  N   . LYS D 2 119 ? -23.87  -9.488  47.812  1   36.12  ? 289 LYS D N   1 
ATOM   7860 C  CA  . LYS D 2 119 ? -23.09  -8.94   46.721  1   37.36  ? 289 LYS D CA  1 
ATOM   7861 C  C   . LYS D 2 119 ? -23.259 -9.766  45.446  1   32.31  ? 289 LYS D C   1 
ATOM   7862 O  O   . LYS D 2 119 ? -23.32  -9.216  44.35   1   28.17  ? 289 LYS D O   1 
ATOM   7863 C  CB  . LYS D 2 119 ? -21.617 -8.847  47.093  1   40.88  ? 289 LYS D CB  1 
ATOM   7864 C  CG  . LYS D 2 119 ? -20.882 -7.882  46.161  1   47.96  ? 289 LYS D CG  1 
ATOM   7865 C  CD  . LYS D 2 119 ? -19.447 -7.617  46.578  1   52.72  ? 289 LYS D CD  1 
ATOM   7866 C  CE  . LYS D 2 119 ? -18.573 -8.818  46.304  1   55.87  ? 289 LYS D CE  1 
ATOM   7867 N  NZ  . LYS D 2 119 ? -17.164 -8.578  46.696  1   58.85  ? 289 LYS D NZ  1 
ATOM   7868 N  N   . GLN D 2 120 ? -23.349 -11.091 45.591  1   31.32  ? 290 GLN D N   1 
ATOM   7869 C  CA  . GLN D 2 120 ? -23.593 -11.957 44.446  1   32.01  ? 290 GLN D CA  1 
ATOM   7870 C  C   . GLN D 2 120 ? -24.946 -11.689 43.802  1   27.38  ? 290 GLN D C   1 
ATOM   7871 O  O   . GLN D 2 120 ? -25.049 -11.65  42.58   1   24.84  ? 290 GLN D O   1 
ATOM   7872 C  CB  . GLN D 2 120 ? -23.51  -13.431 44.833  1   34.23  ? 290 GLN D CB  1 
ATOM   7873 C  CG  . GLN D 2 120 ? -22.083 -13.926 45.01   1   34.61  ? 290 GLN D CG  1 
ATOM   7874 C  CD  . GLN D 2 120 ? -22.1   -15.37  45.454  1   37.69  ? 290 GLN D CD  1 
ATOM   7875 O  OE1 . GLN D 2 120 ? -22.691 -15.725 46.494  1   35.38  ? 290 GLN D OE1 1 
ATOM   7876 N  NE2 . GLN D 2 120 ? -21.497 -16.243 44.646  1   37.55  ? 290 GLN D NE2 1 
ATOM   7877 N  N   . VAL D 2 121 ? -25.976 -11.517 44.635  1   25.9   ? 291 VAL D N   1 
ATOM   7878 C  CA  . VAL D 2 121 ? -27.298 -11.204 44.128  1   28.66  ? 291 VAL D CA  1 
ATOM   7879 C  C   . VAL D 2 121 ? -27.275 -9.885  43.351  1   29.02  ? 291 VAL D C   1 
ATOM   7880 O  O   . VAL D 2 121 ? -27.793 -9.811  42.242  1   30.1   ? 291 VAL D O   1 
ATOM   7881 C  CB  . VAL D 2 121 ? -28.348 -11.198 45.267  1   29.51  ? 291 VAL D CB  1 
ATOM   7882 C  CG1 . VAL D 2 121 ? -29.692 -10.667 44.769  1   30.36  ? 291 VAL D CG1 1 
ATOM   7883 C  CG2 . VAL D 2 121 ? -28.503 -12.578 45.889  1   27.15  ? 291 VAL D CG2 1 
ATOM   7884 N  N   . LEU D 2 122 ? -26.647 -8.852  43.922  1   32.26  ? 292 LEU D N   1 
ATOM   7885 C  CA  . LEU D 2 122 ? -26.602 -7.538  43.287  1   35.69  ? 292 LEU D CA  1 
ATOM   7886 C  C   . LEU D 2 122 ? -25.804 -7.554  41.983  1   33.04  ? 292 LEU D C   1 
ATOM   7887 O  O   . LEU D 2 122 ? -26.199 -6.927  41.001  1   32.9   ? 292 LEU D O   1 
ATOM   7888 C  CB  . LEU D 2 122 ? -25.997 -6.492  44.233  1   35.44  ? 292 LEU D CB  1 
ATOM   7889 C  CG  . LEU D 2 122 ? -26.831 -6.177  45.473  1   39.76  ? 292 LEU D CG  1 
ATOM   7890 C  CD1 . LEU D 2 122 ? -26.109 -5.215  46.372  1   40.44  ? 292 LEU D CD1 1 
ATOM   7891 C  CD2 . LEU D 2 122 ? -28.2   -5.634  45.086  1   41.77  ? 292 LEU D CD2 1 
ATOM   7892 N  N   . ARG D 2 123 ? -24.687 -8.286  41.971  1   29.06  ? 293 ARG D N   1 
ATOM   7893 C  CA  . ARG D 2 123 ? -23.906 -8.408  40.754  1   31.91  ? 293 ARG D CA  1 
ATOM   7894 C  C   . ARG D 2 123 ? -24.651 -9.18   39.667  1   27.56  ? 293 ARG D C   1 
ATOM   7895 O  O   . ARG D 2 123 ? -24.595 -8.796  38.503  1   25.92  ? 293 ARG D O   1 
ATOM   7896 C  CB  . ARG D 2 123 ? -22.539 -9.027  41.045  1   35.63  ? 293 ARG D CB  1 
ATOM   7897 C  CG  . ARG D 2 123 ? -21.593 -8.062  41.739  1   37.49  ? 293 ARG D CG  1 
ATOM   7898 C  CD  . ARG D 2 123 ? -20.179 -8.476  41.504  1   48.9   ? 293 ARG D CD  1 
ATOM   7899 N  NE  . ARG D 2 123 ? -19.282 -7.861  42.472  1   66.05  ? 293 ARG D NE  1 
ATOM   7900 C  CZ  . ARG D 2 123 ? -18.293 -7.027  42.172  1   76.36  ? 293 ARG D CZ  1 
ATOM   7901 N  NH1 . ARG D 2 123 ? -18.176 -6.496  40.963  1   82.12  ? 293 ARG D NH1 1 
ATOM   7902 N  NH2 . ARG D 2 123 ? -17.409 -6.704  43.115  1   67.14  ? 293 ARG D NH2 1 
ATOM   7903 N  N   . MET D 2 124 ? -25.382 -10.229 40.052  1   27.11  ? 294 MET D N   1 
ATOM   7904 C  CA  . MET D 2 124 ? -26.177 -10.998 39.102  1   27.43  ? 294 MET D CA  1 
ATOM   7905 C  C   . MET D 2 124 ? -27.313 -10.139 38.565  1   26.28  ? 294 MET D C   1 
ATOM   7906 O  O   . MET D 2 124 ? -27.622 -10.21  37.375  1   27.49  ? 294 MET D O   1 
ATOM   7907 C  CB  . MET D 2 124 ? -26.744 -12.281 39.727  1   26.33  ? 294 MET D CB  1 
ATOM   7908 C  CG  . MET D 2 124 ? -27.587 -13.123 38.761  1   27.55  ? 294 MET D CG  1 
ATOM   7909 S  SD  . MET D 2 124 ? -26.651 -13.835 37.356  1   29.69  ? 294 MET D SD  1 
ATOM   7910 C  CE  . MET D 2 124 ? -25.82  -15.23  38.163  1   29.37  ? 294 MET D CE  1 
ATOM   7911 N  N   . GLU D 2 125 ? -27.92  -9.323  39.439  1   25.52  ? 295 GLU D N   1 
ATOM   7912 C  CA  . GLU D 2 125 ? -28.905 -8.343  38.997  1   26.88  ? 295 GLU D CA  1 
ATOM   7913 C  C   . GLU D 2 125 ? -28.375 -7.524  37.815  1   25.38  ? 295 GLU D C   1 
ATOM   7914 O  O   . GLU D 2 125 ? -29.009 -7.444  36.765  1   27.16  ? 295 GLU D O   1 
ATOM   7915 C  CB  . GLU D 2 125 ? -29.322 -7.4    40.151  1   27.76  ? 295 GLU D CB  1 
ATOM   7916 C  CG  . GLU D 2 125 ? -30.363 -6.378  39.74   1   27.16  ? 295 GLU D CG  1 
ATOM   7917 C  CD  . GLU D 2 125 ? -30.758 -5.372  40.798  1   29.66  ? 295 GLU D CD  1 
ATOM   7918 O  OE1 . GLU D 2 125 ? -29.891 -4.571  41.233  1   30.28  ? 295 GLU D OE1 1 
ATOM   7919 O  OE2 . GLU D 2 125 ? -31.952 -5.378  41.181  1   26.9   ? 295 GLU D OE2 1 
ATOM   7920 N  N   . HIS D 2 126 ? -27.201 -6.922  37.994  1   25.48  ? 296 HIS D N   1 
ATOM   7921 C  CA  . HIS D 2 126 ? -26.598 -6.113  36.947  1   29.46  ? 296 HIS D CA  1 
ATOM   7922 C  C   . HIS D 2 126 ? -26.315 -6.937  35.683  1   29.8   ? 296 HIS D C   1 
ATOM   7923 O  O   . HIS D 2 126 ? -26.614 -6.509  34.563  1   29.35  ? 296 HIS D O   1 
ATOM   7924 C  CB  . HIS D 2 126 ? -25.313 -5.401  37.451  1   28.03  ? 296 HIS D CB  1 
ATOM   7925 C  CG  . HIS D 2 126 ? -24.982 -4.188  36.633  1   32.24  ? 296 HIS D CG  1 
ATOM   7926 N  ND1 . HIS D 2 126 ? -23.989 -3.303  37.016  1   33.18  ? 296 HIS D ND1 1 
ATOM   7927 C  CD2 . HIS D 2 126 ? -25.566 -3.712  35.498  1   33.66  ? 296 HIS D CD2 1 
ATOM   7928 C  CE1 . HIS D 2 126 ? -23.983 -2.338  36.105  1   31.57  ? 296 HIS D CE1 1 
ATOM   7929 N  NE2 . HIS D 2 126 ? -24.919 -2.544  35.174  1   33.23  ? 296 HIS D NE2 1 
ATOM   7930 N  N   . LEU D 2 127 ? -25.77  -8.145  35.857  1   29.81  ? 297 LEU D N   1 
ATOM   7931 C  CA  . LEU D 2 127 ? -25.483 -8.996  34.716  1   29.77  ? 297 LEU D CA  1 
ATOM   7932 C  C   . LEU D 2 127 ? -26.763 -9.318  33.941  1   27.27  ? 297 LEU D C   1 
ATOM   7933 O  O   . LEU D 2 127 ? -26.782 -9.228  32.717  1   28.36  ? 297 LEU D O   1 
ATOM   7934 C  CB  . LEU D 2 127 ? -24.78  -10.294 35.146  1   29.3   ? 297 LEU D CB  1 
ATOM   7935 C  CG  . LEU D 2 127 ? -24.408 -11.251 33.975  1   28.17  ? 297 LEU D CG  1 
ATOM   7936 C  CD1 . LEU D 2 127 ? -23.383 -10.607 33.03   1   27.22  ? 297 LEU D CD1 1 
ATOM   7937 C  CD2 . LEU D 2 127 ? -23.893 -12.57  34.485  1   26.06  ? 297 LEU D CD2 1 
ATOM   7938 N  N   . VAL D 2 128 ? -27.839 -9.661  34.651  1   27.31  ? 298 VAL D N   1 
ATOM   7939 C  CA  . VAL D 2 128 ? -29.098 -9.945  33.986  1   27.65  ? 298 VAL D CA  1 
ATOM   7940 C  C   . VAL D 2 128 ? -29.601 -8.738  33.201  1   29.04  ? 298 VAL D C   1 
ATOM   7941 O  O   . VAL D 2 128 ? -30.07  -8.892  32.071  1   33.88  ? 298 VAL D O   1 
ATOM   7942 C  CB  . VAL D 2 128 ? -30.154 -10.487 34.963  1   28.44  ? 298 VAL D CB  1 
ATOM   7943 C  CG1 . VAL D 2 128 ? -31.529 -10.591 34.297  1   31.51  ? 298 VAL D CG1 1 
ATOM   7944 C  CG2 . VAL D 2 128 ? -29.729 -11.846 35.51   1   28.13  ? 298 VAL D CG2 1 
ATOM   7945 N  N   . LEU D 2 129 ? -29.484 -7.537  33.784  1   30.46  ? 299 LEU D N   1 
ATOM   7946 C  CA  . LEU D 2 129 ? -29.894 -6.325  33.09   1   30.04  ? 299 LEU D CA  1 
ATOM   7947 C  C   . LEU D 2 129 ? -29.072 -6.135  31.817  1   31     ? 299 LEU D C   1 
ATOM   7948 O  O   . LEU D 2 129 ? -29.606 -5.719  30.787  1   31.06  ? 299 LEU D O   1 
ATOM   7949 C  CB  . LEU D 2 129 ? -29.77  -5.07   33.996  1   32.31  ? 299 LEU D CB  1 
ATOM   7950 C  CG  . LEU D 2 129 ? -30.836 -4.909  35.079  1   34.43  ? 299 LEU D CG  1 
ATOM   7951 C  CD1 . LEU D 2 129 ? -30.5   -3.782  36.029  1   32.51  ? 299 LEU D CD1 1 
ATOM   7952 C  CD2 . LEU D 2 129 ? -32.21  -4.663  34.47   1   32.85  ? 299 LEU D CD2 1 
ATOM   7953 N  N   . LYS D 2 130 ? -27.768 -6.435  31.889  1   32.61  ? 300 LYS D N   1 
ATOM   7954 C  CA  . LYS D 2 130 ? -26.907 -6.26   30.731  1   33.93  ? 300 LYS D CA  1 
ATOM   7955 C  C   . LYS D 2 130 ? -27.311 -7.239  29.631  1   32.83  ? 300 LYS D C   1 
ATOM   7956 O  O   . LYS D 2 130 ? -27.453 -6.84   28.48   1   31.58  ? 300 LYS D O   1 
ATOM   7957 C  CB  . LYS D 2 130 ? -25.419 -6.418  31.096  1   39.15  ? 300 LYS D CB  1 
ATOM   7958 C  CG  . LYS D 2 130 ? -24.814 -5.212  31.827  1   41.24  ? 300 LYS D CG  1 
ATOM   7959 C  CD  . LYS D 2 130 ? -23.328 -5.409  32.188  1   49.62  ? 300 LYS D CD  1 
ATOM   7960 C  CE  . LYS D 2 130 ? -22.835 -4.439  33.243  1   60.59  ? 300 LYS D CE  1 
ATOM   7961 N  NZ  . LYS D 2 130 ? -21.416 -4.684  33.617  1   66.2   ? 300 LYS D NZ  1 
ATOM   7962 N  N   . VAL D 2 131 ? -27.532 -8.507  30.001  1   31.12  ? 301 VAL D N   1 
ATOM   7963 C  CA  . VAL D 2 131 ? -27.87  -9.544  29.037  1   32.03  ? 301 VAL D CA  1 
ATOM   7964 C  C   . VAL D 2 131 ? -29.215 -9.302  28.356  1   32.29  ? 301 VAL D C   1 
ATOM   7965 O  O   . VAL D 2 131 ? -29.34  -9.559  27.171  1   30.05  ? 301 VAL D O   1 
ATOM   7966 C  CB  . VAL D 2 131 ? -27.808 -10.938 29.709  1   33.25  ? 301 VAL D CB  1 
ATOM   7967 C  CG1 . VAL D 2 131 ? -28.454 -12.013 28.847  1   29.94  ? 301 VAL D CG1 1 
ATOM   7968 C  CG2 . VAL D 2 131 ? -26.358 -11.309 30.052  1   34.45  ? 301 VAL D CG2 1 
ATOM   7969 N  N   . LEU D 2 132 ? -30.211 -8.803  29.097  1   33.76  ? 302 LEU D N   1 
ATOM   7970 C  CA  . LEU D 2 132 ? -31.516 -8.502  28.521  1   31.87  ? 302 LEU D CA  1 
ATOM   7971 C  C   . LEU D 2 132 ? -31.558 -7.091  27.927  1   30.9   ? 302 LEU D C   1 
ATOM   7972 O  O   . LEU D 2 132 ? -32.599 -6.645  27.465  1   28.88  ? 302 LEU D O   1 
ATOM   7973 C  CB  . LEU D 2 132 ? -32.604 -8.627  29.613  1   30.93  ? 302 LEU D CB  1 
ATOM   7974 C  CG  . LEU D 2 132 ? -32.726 -9.979  30.311  1   34.82  ? 302 LEU D CG  1 
ATOM   7975 C  CD1 . LEU D 2 132 ? -33.912 -10.02  31.245  1   34.2   ? 302 LEU D CD1 1 
ATOM   7976 C  CD2 . LEU D 2 132 ? -32.869 -11.103 29.337  1   35.88  ? 302 LEU D CD2 1 
ATOM   7977 N  N   . ALA D 2 133 ? -30.433 -6.37   28.001  1   30.5   ? 303 ALA D N   1 
ATOM   7978 C  CA  . ALA D 2 133 ? -30.348 -4.972  27.606  1   30.55  ? 303 ALA D CA  1 
ATOM   7979 C  C   . ALA D 2 133 ? -31.495 -4.107  28.134  1   30.56  ? 303 ALA D C   1 
ATOM   7980 O  O   . ALA D 2 133 ? -31.977 -3.229  27.419  1   29.54  ? 303 ALA D O   1 
ATOM   7981 C  CB  . ALA D 2 133 ? -30.257 -4.879  26.078  1   28.4   ? 303 ALA D CB  1 
ATOM   7982 N  N   . PHE D 2 134 ? -31.909 -4.356  29.387  1   31.39  ? 304 PHE D N   1 
ATOM   7983 C  CA  . PHE D 2 134 ? -33.027 -3.67   30.027  1   32.87  ? 304 PHE D CA  1 
ATOM   7984 C  C   . PHE D 2 134 ? -34.401 -3.833  29.374  1   33.06  ? 304 PHE D C   1 
ATOM   7985 O  O   . PHE D 2 134 ? -35.316 -3.085  29.704  1   34.16  ? 304 PHE D O   1 
ATOM   7986 C  CB  . PHE D 2 134 ? -32.755 -2.143  30.143  1   34.22  ? 304 PHE D CB  1 
ATOM   7987 C  CG  . PHE D 2 134 ? -31.866 -1.73   31.284  1   36.71  ? 304 PHE D CG  1 
ATOM   7988 C  CD1 . PHE D 2 134 ? -30.495 -1.783  31.171  1   34.51  ? 304 PHE D CD1 1 
ATOM   7989 C  CD2 . PHE D 2 134 ? -32.411 -1.257  32.467  1   41.88  ? 304 PHE D CD2 1 
ATOM   7990 C  CE1 . PHE D 2 134 ? -29.684 -1.382  32.23   1   39.4   ? 304 PHE D CE1 1 
ATOM   7991 C  CE2 . PHE D 2 134 ? -31.594 -0.849  33.519  1   40.49  ? 304 PHE D CE2 1 
ATOM   7992 C  CZ  . PHE D 2 134 ? -30.24  -0.91   33.392  1   38.88  ? 304 PHE D CZ  1 
ATOM   7993 N  N   . ASP D 2 135 ? -34.573 -4.797  28.457  1   36.41  ? 305 ASP D N   1 
ATOM   7994 C  CA  . ASP D 2 135 ? -35.892 -5.068  27.892  1   37.02  ? 305 ASP D CA  1 
ATOM   7995 C  C   . ASP D 2 135 ? -36.717 -5.892  28.873  1   32.9   ? 305 ASP D C   1 
ATOM   7996 O  O   . ASP D 2 135 ? -36.805 -7.105  28.717  1   31.15  ? 305 ASP D O   1 
ATOM   7997 C  CB  . ASP D 2 135 ? -35.824 -5.831  26.576  1   42.1   ? 305 ASP D CB  1 
ATOM   7998 C  CG  . ASP D 2 135 ? -35.461 -5.011  25.372  1   50.23  ? 305 ASP D CG  1 
ATOM   7999 O  OD1 . ASP D 2 135 ? -34.812 -3.945  25.54   1   53.36  ? 305 ASP D OD1 1 
ATOM   8000 O  OD2 . ASP D 2 135 ? -35.812 -5.425  24.265  1   67.14  ? 305 ASP D OD2 1 
ATOM   8001 N  N   . LEU D 2 136 ? -37.311 -5.226  29.878  1   31.11  ? 306 LEU D N   1 
ATOM   8002 C  CA  . LEU D 2 136 ? -38.021 -5.911  30.944  1   31.76  ? 306 LEU D CA  1 
ATOM   8003 C  C   . LEU D 2 136 ? -39.544 -5.893  30.804  1   32.83  ? 306 LEU D C   1 
ATOM   8004 O  O   . LEU D 2 136 ? -40.222 -6.709  31.432  1   34.21  ? 306 LEU D O   1 
ATOM   8005 C  CB  . LEU D 2 136 ? -37.624 -5.299  32.291  1   36.41  ? 306 LEU D CB  1 
ATOM   8006 C  CG  . LEU D 2 136 ? -36.134 -5.402  32.703  1   40.03  ? 306 LEU D CG  1 
ATOM   8007 C  CD1 . LEU D 2 136 ? -36.002 -5.234  34.191  1   45.42  ? 306 LEU D CD1 1 
ATOM   8008 C  CD2 . LEU D 2 136 ? -35.49  -6.717  32.281  1   38.89  ? 306 LEU D CD2 1 
ATOM   8009 N  N   . ALA D 2 137 ? -40.089 -4.991  29.974  1   32.6   ? 307 ALA D N   1 
ATOM   8010 C  CA  . ALA D 2 137 ? -41.533 -4.911  29.808  1   32.33  ? 307 ALA D CA  1 
ATOM   8011 C  C   . ALA D 2 137 ? -42.028 -5.987  28.844  1   30.24  ? 307 ALA D C   1 
ATOM   8012 O  O   . ALA D 2 137 ? -42.557 -5.671  27.782  1   29.8   ? 307 ALA D O   1 
ATOM   8013 C  CB  . ALA D 2 137 ? -41.952 -3.524  29.342  1   31.67  ? 307 ALA D CB  1 
ATOM   8014 N  N   . ALA D 2 138 ? -41.885 -7.256  29.253  1   28.89  ? 308 ALA D N   1 
ATOM   8015 C  CA  . ALA D 2 138 ? -42.245 -8.393  28.415  1   28.59  ? 308 ALA D CA  1 
ATOM   8016 C  C   . ALA D 2 138 ? -43.719 -8.708  28.585  1   32.17  ? 308 ALA D C   1 
ATOM   8017 O  O   . ALA D 2 138 ? -44.237 -8.664  29.698  1   36.63  ? 308 ALA D O   1 
ATOM   8018 C  CB  . ALA D 2 138 ? -41.437 -9.633  28.763  1   28.35  ? 308 ALA D CB  1 
ATOM   8019 N  N   . PRO D 2 139 ? -44.437 -9.04   27.492  1   32.7   ? 309 PRO D N   1 
ATOM   8020 C  CA  . PRO D 2 139 ? -45.805 -9.535  27.608  1   32.34  ? 309 PRO D CA  1 
ATOM   8021 C  C   . PRO D 2 139 ? -45.822 -10.909 28.269  1   30.11  ? 309 PRO D C   1 
ATOM   8022 O  O   . PRO D 2 139 ? -44.999 -11.764 27.961  1   28.02  ? 309 PRO D O   1 
ATOM   8023 C  CB  . PRO D 2 139 ? -46.296 -9.552  26.161  1   32.46  ? 309 PRO D CB  1 
ATOM   8024 C  CG  . PRO D 2 139 ? -45.303 -8.693  25.386  1   33.51  ? 309 PRO D CG  1 
ATOM   8025 C  CD  . PRO D 2 139 ? -44.008 -8.889  26.095  1   33.63  ? 309 PRO D CD  1 
ATOM   8026 N  N   . THR D 2 140 ? -46.783 -11.092 29.176  1   29.68  ? 310 THR D N   1 
ATOM   8027 C  CA  . THR D 2 140 ? -46.951 -12.33  29.913  1   27.96  ? 310 THR D CA  1 
ATOM   8028 C  C   . THR D 2 140 ? -48.255 -12.999 29.514  1   28.98  ? 310 THR D C   1 
ATOM   8029 O  O   . THR D 2 140 ? -49.13  -12.362 28.924  1   28.56  ? 310 THR D O   1 
ATOM   8030 C  CB  . THR D 2 140 ? -46.957 -12.055 31.421  1   25.27  ? 310 THR D CB  1 
ATOM   8031 O  OG1 . THR D 2 140 ? -48.059 -11.202 31.722  1   24.83  ? 310 THR D OG1 1 
ATOM   8032 C  CG2 . THR D 2 140 ? -45.67  -11.43  31.891  1   24.52  ? 310 THR D CG2 1 
ATOM   8033 N  N   . ILE D 2 141 ? -48.377 -14.273 29.889  1   29.13  ? 311 ILE D N   1 
ATOM   8034 C  CA  . ILE D 2 141 ? -49.638 -14.977 29.769  1   30.92  ? 311 ILE D CA  1 
ATOM   8035 C  C   . ILE D 2 141 ? -50.763 -14.139 30.37   1   32.45  ? 311 ILE D C   1 
ATOM   8036 O  O   . ILE D 2 141 ? -51.84  -14.04  29.787  1   35.71  ? 311 ILE D O   1 
ATOM   8037 C  CB  . ILE D 2 141 ? -49.53  -16.373 30.412  1   30.49  ? 311 ILE D CB  1 
ATOM   8038 C  CG1 . ILE D 2 141 ? -48.643 -17.293 29.549  1   30.79  ? 311 ILE D CG1 1 
ATOM   8039 C  CG2 . ILE D 2 141 ? -50.925 -16.967 30.657  1   29.18  ? 311 ILE D CG2 1 
ATOM   8040 C  CD1 . ILE D 2 141 ? -48.234 -18.566 30.21   1   32.93  ? 311 ILE D CD1 1 
ATOM   8041 N  N   . ASN D 2 142 ? -50.5   -13.52  31.528  1   34.07  ? 312 ASN D N   1 
ATOM   8042 C  CA  . ASN D 2 142 ? -51.533 -12.806 32.265  1   32.53  ? 312 ASN D CA  1 
ATOM   8043 C  C   . ASN D 2 142 ? -52.036 -11.54  31.583  1   29.88  ? 312 ASN D C   1 
ATOM   8044 O  O   . ASN D 2 142 ? -53.224 -11.244 31.634  1   29.86  ? 312 ASN D O   1 
ATOM   8045 C  CB  . ASN D 2 142 ? -51.056 -12.472 33.662  1   34.56  ? 312 ASN D CB  1 
ATOM   8046 C  CG  . ASN D 2 142 ? -51.16  -13.658 34.567  1   34.81  ? 312 ASN D CG  1 
ATOM   8047 O  OD1 . ASN D 2 142 ? -51.214 -14.81  34.114  1   32.08  ? 312 ASN D OD1 1 
ATOM   8048 N  ND2 . ASN D 2 142 ? -51.198 -13.396 35.865  1   37.34  ? 312 ASN D ND2 1 
ATOM   8049 N  N   . GLN D 2 143 ? -51.127 -10.795 30.955  1   29.72  ? 313 GLN D N   1 
ATOM   8050 C  CA  . GLN D 2 143 ? -51.505 -9.593  30.23   1   29.48  ? 313 GLN D CA  1 
ATOM   8051 C  C   . GLN D 2 143 ? -52.489 -9.92   29.106  1   31.4   ? 313 GLN D C   1 
ATOM   8052 O  O   . GLN D 2 143 ? -53.336 -9.098  28.767  1   30.74  ? 313 GLN D O   1 
ATOM   8053 C  CB  . GLN D 2 143 ? -50.275 -8.886  29.651  1   28.25  ? 313 GLN D CB  1 
ATOM   8054 C  CG  . GLN D 2 143 ? -49.455 -8.162  30.701  1   28.8   ? 313 GLN D CG  1 
ATOM   8055 C  CD  . GLN D 2 143 ? -48.207 -7.53   30.122  1   28.44  ? 313 GLN D CD  1 
ATOM   8056 O  OE1 . GLN D 2 143 ? -48.249 -6.671  29.199  1   26.33  ? 313 GLN D OE1 1 
ATOM   8057 N  NE2 . GLN D 2 143 ? -47.071 -7.944  30.655  1   28.6   ? 313 GLN D NE2 1 
ATOM   8058 N  N   . PHE D 2 144 ? -52.353 -11.114 28.513  1   29.13  ? 314 PHE D N   1 
ATOM   8059 C  CA  . PHE D 2 144 ? -53.281 -11.554 27.484  1   29.69  ? 314 PHE D CA  1 
ATOM   8060 C  C   . PHE D 2 144 ? -54.582 -12.038 28.122  1   30.38  ? 314 PHE D C   1 
ATOM   8061 O  O   . PHE D 2 144 ? -55.662 -11.642 27.682  1   29.35  ? 314 PHE D O   1 
ATOM   8062 C  CB  . PHE D 2 144 ? -52.64  -12.618 26.58   1   28.96  ? 314 PHE D CB  1 
ATOM   8063 C  CG  . PHE D 2 144 ? -51.65  -12.026 25.607  1   29.51  ? 314 PHE D CG  1 
ATOM   8064 C  CD1 . PHE D 2 144 ? -52.08  -11.286 24.516  1   32.43  ? 314 PHE D CD1 1 
ATOM   8065 C  CD2 . PHE D 2 144 ? -50.286 -12.17  25.804  1   29.61  ? 314 PHE D CD2 1 
ATOM   8066 C  CE1 . PHE D 2 144 ? -51.159 -10.726 23.625  1   33.03  ? 314 PHE D CE1 1 
ATOM   8067 C  CE2 . PHE D 2 144 ? -49.373 -11.605 24.918  1   29.7   ? 314 PHE D CE2 1 
ATOM   8068 C  CZ  . PHE D 2 144 ? -49.811 -10.887 23.835  1   31.16  ? 314 PHE D CZ  1 
ATOM   8069 N  N   . LEU D 2 145 ? -54.464 -12.854 29.18   1   31.85  ? 315 LEU D N   1 
ATOM   8070 C  CA  . LEU D 2 145 ? -55.62  -13.404 29.878  1   32.66  ? 315 LEU D CA  1 
ATOM   8071 C  C   . LEU D 2 145 ? -56.613 -12.333 30.321  1   31.45  ? 315 LEU D C   1 
ATOM   8072 O  O   . LEU D 2 145 ? -57.808 -12.472 30.062  1   27.11  ? 315 LEU D O   1 
ATOM   8073 C  CB  . LEU D 2 145 ? -55.196 -14.209 31.119  1   33.15  ? 315 LEU D CB  1 
ATOM   8074 C  CG  . LEU D 2 145 ? -54.804 -15.666 30.89   1   32.11  ? 315 LEU D CG  1 
ATOM   8075 C  CD1 . LEU D 2 145 ? -54.507 -16.358 32.206  1   31.86  ? 315 LEU D CD1 1 
ATOM   8076 C  CD2 . LEU D 2 145 ? -55.872 -16.41  30.166  1   33.89  ? 315 LEU D CD2 1 
ATOM   8077 N  N   . THR D 2 146 ? -56.111 -11.278 30.983  1   32.14  ? 316 THR D N   1 
ATOM   8078 C  CA  . THR D 2 146 ? -56.975 -10.232 31.512  1   34.65  ? 316 THR D CA  1 
ATOM   8079 C  C   . THR D 2 146 ? -57.759 -9.547  30.393  1   38.27  ? 316 THR D C   1 
ATOM   8080 O  O   . THR D 2 146 ? -58.908 -9.163  30.6    1   41.93  ? 316 THR D O   1 
ATOM   8081 C  CB  . THR D 2 146 ? -56.201 -9.194  32.354  1   36.56  ? 316 THR D CB  1 
ATOM   8082 O  OG1 . THR D 2 146 ? -55.229 -8.542  31.541  1   39.23  ? 316 THR D OG1 1 
ATOM   8083 C  CG2 . THR D 2 146 ? -55.521 -9.804  33.579  1   36.12  ? 316 THR D CG2 1 
ATOM   8084 N  N   . GLN D 2 147 ? -57.146 -9.408  29.208  1   38.4   ? 317 GLN D N   1 
ATOM   8085 C  CA  . GLN D 2 147 ? -57.842 -8.859  28.052  1   39.73  ? 317 GLN D CA  1 
ATOM   8086 C  C   . GLN D 2 147 ? -58.916 -9.8    27.515  1   34.95  ? 317 GLN D C   1 
ATOM   8087 O  O   . GLN D 2 147 ? -59.982 -9.35   27.103  1   34.51  ? 317 GLN D O   1 
ATOM   8088 C  CB  . GLN D 2 147 ? -56.872 -8.534  26.908  1   43.54  ? 317 GLN D CB  1 
ATOM   8089 C  CG  . GLN D 2 147 ? -56.126 -7.243  27.121  1   44.1   ? 317 GLN D CG  1 
ATOM   8090 C  CD  . GLN D 2 147 ? -55.312 -6.855  25.909  1   45.66  ? 317 GLN D CD  1 
ATOM   8091 O  OE1 . GLN D 2 147 ? -55.819 -6.679  24.778  1   46.54  ? 317 GLN D OE1 1 
ATOM   8092 N  NE2 . GLN D 2 147 ? -54.039 -6.686  26.124  1   48.85  ? 317 GLN D NE2 1 
ATOM   8093 N  N   . TYR D 2 148 ? -58.598 -11.098 27.485  1   36.6   ? 318 TYR D N   1 
ATOM   8094 C  CA  . TYR D 2 148 ? -59.539 -12.127 27.067  1   33.03  ? 318 TYR D CA  1 
ATOM   8095 C  C   . TYR D 2 148 ? -60.744 -12.197 28.009  1   32.06  ? 318 TYR D C   1 
ATOM   8096 O  O   . TYR D 2 148 ? -61.867 -12.462 27.574  1   30.91  ? 318 TYR D O   1 
ATOM   8097 C  CB  . TYR D 2 148 ? -58.849 -13.511 27.01   1   30.9   ? 318 TYR D CB  1 
ATOM   8098 C  CG  . TYR D 2 148 ? -57.693 -13.689 26.036  1   30.36  ? 318 TYR D CG  1 
ATOM   8099 C  CD1 . TYR D 2 148 ? -57.433 -12.751 25.043  1   29.4   ? 318 TYR D CD1 1 
ATOM   8100 C  CD2 . TYR D 2 148 ? -56.872 -14.814 26.098  1   30.32  ? 318 TYR D CD2 1 
ATOM   8101 C  CE1 . TYR D 2 148 ? -56.381 -12.921 24.148  1   30.08  ? 318 TYR D CE1 1 
ATOM   8102 C  CE2 . TYR D 2 148 ? -55.818 -14.991 25.212  1   30.35  ? 318 TYR D CE2 1 
ATOM   8103 C  CZ  . TYR D 2 148 ? -55.567 -14.038 24.247  1   31.55  ? 318 TYR D CZ  1 
ATOM   8104 O  OH  . TYR D 2 148 ? -54.515 -14.236 23.384  1   34.25  ? 318 TYR D OH  1 
ATOM   8105 N  N   . PHE D 2 149 ? -60.495 -11.957 29.306  1   33.57  ? 319 PHE D N   1 
ATOM   8106 C  CA  . PHE D 2 149 ? -61.538 -12.002 30.319  1   33.75  ? 319 PHE D CA  1 
ATOM   8107 C  C   . PHE D 2 149 ? -62.665 -11.013 30.029  1   34.87  ? 319 PHE D C   1 
ATOM   8108 O  O   . PHE D 2 149 ? -63.823 -11.299 30.328  1   35.17  ? 319 PHE D O   1 
ATOM   8109 C  CB  . PHE D 2 149 ? -60.964 -11.75  31.718  1   32.52  ? 319 PHE D CB  1 
ATOM   8110 C  CG  . PHE D 2 149 ? -60.095 -12.836 32.322  1   35.81  ? 319 PHE D CG  1 
ATOM   8111 C  CD1 . PHE D 2 149 ? -59.986 -14.085 31.723  1   37.25  ? 319 PHE D CD1 1 
ATOM   8112 C  CD2 . PHE D 2 149 ? -59.381 -12.606 33.494  1   35.74  ? 319 PHE D CD2 1 
ATOM   8113 C  CE1 . PHE D 2 149 ? -59.184 -15.082 32.289  1   37.84  ? 319 PHE D CE1 1 
ATOM   8114 C  CE2 . PHE D 2 149 ? -58.576 -13.601 34.049  1   35.58  ? 319 PHE D CE2 1 
ATOM   8115 C  CZ  . PHE D 2 149 ? -58.481 -14.831 33.447  1   38.34  ? 319 PHE D CZ  1 
ATOM   8116 N  N   . LEU D 2 150 ? -62.328 -9.882  29.399  1   36.29  ? 320 LEU D N   1 
ATOM   8117 C  CA  . LEU D 2 150 ? -63.31  -8.871  29.031  1   41.3   ? 320 LEU D CA  1 
ATOM   8118 C  C   . LEU D 2 150 ? -64.337 -9.325  27.988  1   37.66  ? 320 LEU D C   1 
ATOM   8119 O  O   . LEU D 2 150 ? -65.294 -8.606  27.716  1   36.17  ? 320 LEU D O   1 
ATOM   8120 C  CB  . LEU D 2 150 ? -62.568 -7.621  28.497  1   42.81  ? 320 LEU D CB  1 
ATOM   8121 C  CG  . LEU D 2 150 ? -61.634 -6.922  29.477  1   44.17  ? 320 LEU D CG  1 
ATOM   8122 C  CD1 . LEU D 2 150 ? -60.838 -5.828  28.782  1   42.53  ? 320 LEU D CD1 1 
ATOM   8123 C  CD2 . LEU D 2 150 ? -62.412 -6.34   30.656  1   44.64  ? 320 LEU D CD2 1 
ATOM   8124 N  N   . HIS D 2 151 ? -64.138 -10.506 27.391  1   37.07  ? 321 HIS D N   1 
ATOM   8125 C  CA  . HIS D 2 151 ? -65.109 -11.044 26.452  1   36.51  ? 321 HIS D CA  1 
ATOM   8126 C  C   . HIS D 2 151 ? -66.136 -11.99  27.081  1   37.04  ? 321 HIS D C   1 
ATOM   8127 O  O   . HIS D 2 151 ? -67.084 -12.388 26.408  1   35.19  ? 321 HIS D O   1 
ATOM   8128 C  CB  . HIS D 2 151 ? -64.371 -11.707 25.275  1   37.77  ? 321 HIS D CB  1 
ATOM   8129 C  CG  . HIS D 2 151 ? -63.671 -10.714 24.396  1   38.51  ? 321 HIS D CG  1 
ATOM   8130 N  ND1 . HIS D 2 151 ? -64.066 -10.503 23.08   1   39.62  ? 321 HIS D ND1 1 
ATOM   8131 C  CD2 . HIS D 2 151 ? -62.634 -9.891  24.674  1   37.74  ? 321 HIS D CD2 1 
ATOM   8132 C  CE1 . HIS D 2 151 ? -63.26  -9.563  22.605  1   38.38  ? 321 HIS D CE1 1 
ATOM   8133 N  NE2 . HIS D 2 151 ? -62.385 -9.163  23.535  1   37.68  ? 321 HIS D NE2 1 
ATOM   8134 N  N   . GLN D 2 152 ? -65.964 -12.313 28.371  1   38.57  ? 322 GLN D N   1 
ATOM   8135 C  CA  . GLN D 2 152 ? -66.967 -13.057 29.115  1   41.14  ? 322 GLN D CA  1 
ATOM   8136 C  C   . GLN D 2 152 ? -68.252 -12.249 29.271  1   44.54  ? 322 GLN D C   1 
ATOM   8137 O  O   . GLN D 2 152 ? -68.208 -11.035 29.447  1   45.69  ? 322 GLN D O   1 
ATOM   8138 C  CB  . GLN D 2 152 ? -66.469 -13.391 30.518  1   40.32  ? 322 GLN D CB  1 
ATOM   8139 C  CG  . GLN D 2 152 ? -65.342 -14.373 30.609  1   41.51  ? 322 GLN D CG  1 
ATOM   8140 C  CD  . GLN D 2 152 ? -64.844 -14.415 32.041  1   45.93  ? 322 GLN D CD  1 
ATOM   8141 O  OE1 . GLN D 2 152 ? -65.133 -15.354 32.816  1   50.06  ? 322 GLN D OE1 1 
ATOM   8142 N  NE2 . GLN D 2 152 ? -64.108 -13.38  32.444  1   42.56  ? 322 GLN D NE2 1 
ATOM   8143 N  N   . GLN D 2 153 ? -69.392 -12.948 29.223  1   46.31  ? 323 GLN D N   1 
ATOM   8144 C  CA  . GLN D 2 153 ? -70.707 -12.339 29.366  1   47.8   ? 323 GLN D CA  1 
ATOM   8145 C  C   . GLN D 2 153 ? -71.62  -13.231 30.21   1   41.79  ? 323 GLN D C   1 
ATOM   8146 O  O   . GLN D 2 153 ? -72.226 -14.165 29.686  1   41.88  ? 323 GLN D O   1 
ATOM   8147 C  CB  . GLN D 2 153 ? -71.362 -12.132 27.988  1   51.66  ? 323 GLN D CB  1 
ATOM   8148 C  CG  . GLN D 2 153 ? -70.656 -11.177 27.026  1   53.22  ? 323 GLN D CG  1 
ATOM   8149 C  CD  . GLN D 2 153 ? -71.189 -11.351 25.62   1   52.42  ? 323 GLN D CD  1 
ATOM   8150 O  OE1 . GLN D 2 153 ? -71.266 -12.473 25.108  1   51.27  ? 323 GLN D OE1 1 
ATOM   8151 N  NE2 . GLN D 2 153 ? -71.582 -10.262 24.957  1   52.7   ? 323 GLN D NE2 1 
ATOM   8152 N  N   . PRO D 2 154 ? -71.728 -13.032 31.547  1   36.22  ? 324 PRO D N   1 
ATOM   8153 C  CA  . PRO D 2 154 ? -70.936 -12.046 32.285  1   34.2   ? 324 PRO D CA  1 
ATOM   8154 C  C   . PRO D 2 154 ? -69.62  -12.657 32.756  1   33.17  ? 324 PRO D C   1 
ATOM   8155 O  O   . PRO D 2 154 ? -69.345 -13.824 32.468  1   29.34  ? 324 PRO D O   1 
ATOM   8156 C  CB  . PRO D 2 154 ? -71.84  -11.728 33.463  1   33.98  ? 324 PRO D CB  1 
ATOM   8157 C  CG  . PRO D 2 154 ? -72.511 -13.081 33.762  1   33.56  ? 324 PRO D CG  1 
ATOM   8158 C  CD  . PRO D 2 154 ? -72.606 -13.812 32.437  1   34.4   ? 324 PRO D CD  1 
ATOM   8159 N  N   . ALA D 2 155 ? -68.837 -11.869 33.504  1   33.78  ? 325 ALA D N   1 
ATOM   8160 C  CA  . ALA D 2 155 ? -67.615 -12.354 34.128  1   33.17  ? 325 ALA D CA  1 
ATOM   8161 C  C   . ALA D 2 155 ? -67.912 -13.508 35.085  1   34.09  ? 325 ALA D C   1 
ATOM   8162 O  O   . ALA D 2 155 ? -68.913 -13.474 35.794  1   34.81  ? 325 ALA D O   1 
ATOM   8163 C  CB  . ALA D 2 155 ? -66.922 -11.223 34.868  1   31.32  ? 325 ALA D CB  1 
ATOM   8164 N  N   . ASN D 2 156 ? -67.045 -14.532 35.079  1   35.33  ? 326 ASN D N   1 
ATOM   8165 C  CA  . ASN D 2 156 ? -67.143 -15.659 35.996  1   35.19  ? 326 ASN D CA  1 
ATOM   8166 C  C   . ASN D 2 156 ? -65.779 -15.893 36.638  1   35.58  ? 326 ASN D C   1 
ATOM   8167 O  O   . ASN D 2 156 ? -64.806 -16.148 35.936  1   34.86  ? 326 ASN D O   1 
ATOM   8168 C  CB  . ASN D 2 156 ? -67.621 -16.928 35.282  1   36.03  ? 326 ASN D CB  1 
ATOM   8169 C  CG  . ASN D 2 156 ? -67.784 -18.134 36.203  1   36.8   ? 326 ASN D CG  1 
ATOM   8170 O  OD1 . ASN D 2 156 ? -66.856 -18.551 36.921  1   35.58  ? 326 ASN D OD1 1 
ATOM   8171 N  ND2 . ASN D 2 156 ? -68.97  -18.727 36.202  1   36.26  ? 326 ASN D ND2 1 
ATOM   8172 N  N   . CYS D 2 157 ? -65.744 -15.822 37.975  1   37.1   ? 327 CYS D N   1 
ATOM   8173 C  CA  . CYS D 2 157 ? -64.511 -15.826 38.745  1   37.79  ? 327 CYS D CA  1 
ATOM   8174 C  C   . CYS D 2 157 ? -63.802 -17.182 38.753  1   37.09  ? 327 CYS D C   1 
ATOM   8175 O  O   . CYS D 2 157 ? -62.577 -17.236 38.826  1   37.75  ? 327 CYS D O   1 
ATOM   8176 C  CB  . CYS D 2 157 ? -64.785 -15.329 40.166  1   39.22  ? 327 CYS D CB  1 
ATOM   8177 S  SG  . CYS D 2 157 ? -65.913 -16.381 41.127  1   48.95  ? 327 CYS D SG  1 
ATOM   8178 N  N   . LYS D 2 158 ? -64.564 -18.278 38.679  1   37.18  ? 328 LYS D N   1 
ATOM   8179 C  CA  . LYS D 2 158 ? -63.967 -19.604 38.617  1   39.54  ? 328 LYS D CA  1 
ATOM   8180 C  C   . LYS D 2 158 ? -63.271 -19.821 37.275  1   38.2   ? 328 LYS D C   1 
ATOM   8181 O  O   . LYS D 2 158 ? -62.189 -20.406 37.221  1   37.88  ? 328 LYS D O   1 
ATOM   8182 C  CB  . LYS D 2 158 ? -65.01  -20.689 38.887  1   39.66  ? 328 LYS D CB  1 
ATOM   8183 C  CG  . LYS D 2 158 ? -65.559 -20.589 40.302  1   41.83  ? 328 LYS D CG  1 
ATOM   8184 C  CD  . LYS D 2 158 ? -66.093 -21.884 40.862  1   43.16  ? 328 LYS D CD  1 
ATOM   8185 C  CE  . LYS D 2 158 ? -66.832 -21.631 42.156  1   44.26  ? 328 LYS D CE  1 
ATOM   8186 N  NZ  . LYS D 2 158 ? -67.23  -22.901 42.834  1   45.83  ? 328 LYS D NZ  1 
ATOM   8187 N  N   . VAL D 2 159 ? -63.886 -19.322 36.197  1   35.59  ? 329 VAL D N   1 
ATOM   8188 C  CA  . VAL D 2 159 ? -63.256 -19.324 34.886  1   33.98  ? 329 VAL D CA  1 
ATOM   8189 C  C   . VAL D 2 159 ? -61.949 -18.527 34.927  1   33.96  ? 329 VAL D C   1 
ATOM   8190 O  O   . VAL D 2 159 ? -60.932 -18.978 34.412  1   34.36  ? 329 VAL D O   1 
ATOM   8191 C  CB  . VAL D 2 159 ? -64.233 -18.799 33.805  1   32.69  ? 329 VAL D CB  1 
ATOM   8192 C  CG1 . VAL D 2 159 ? -63.52  -18.528 32.493  1   32.86  ? 329 VAL D CG1 1 
ATOM   8193 C  CG2 . VAL D 2 159 ? -65.389 -19.776 33.599  1   34.03  ? 329 VAL D CG2 1 
ATOM   8194 N  N   . GLU D 2 160 ? -61.97  -17.346 35.554  1   33.55  ? 330 GLU D N   1 
ATOM   8195 C  CA  . GLU D 2 160 ? -60.783 -16.502 35.613  1   36.55  ? 330 GLU D CA  1 
ATOM   8196 C  C   . GLU D 2 160 ? -59.667 -17.165 36.413  1   33.14  ? 330 GLU D C   1 
ATOM   8197 O  O   . GLU D 2 160 ? -58.562 -17.3   35.896  1   34.1   ? 330 GLU D O   1 
ATOM   8198 C  CB  . GLU D 2 160 ? -61.099 -15.118 36.176  1   37.55  ? 330 GLU D CB  1 
ATOM   8199 C  CG  . GLU D 2 160 ? -61.958 -14.318 35.207  1   40.87  ? 330 GLU D CG  1 
ATOM   8200 C  CD  . GLU D 2 160 ? -62.362 -12.936 35.659  1   39.49  ? 330 GLU D CD  1 
ATOM   8201 O  OE1 . GLU D 2 160 ? -61.864 -12.478 36.709  1   42.47  ? 330 GLU D OE1 1 
ATOM   8202 O  OE2 . GLU D 2 160 ? -63.185 -12.313 34.958  1   37.95  ? 330 GLU D OE2 1 
ATOM   8203 N  N   . SER D 2 161 ? -59.975 -17.607 37.64   1   29.94  ? 331 SER D N   1 
ATOM   8204 C  CA  . SER D 2 161 ? -59.007 -18.315 38.466  1   30.11  ? 331 SER D CA  1 
ATOM   8205 C  C   . SER D 2 161 ? -58.473 -19.587 37.812  1   33.59  ? 331 SER D C   1 
ATOM   8206 O  O   . SER D 2 161 ? -57.273 -19.857 37.875  1   38.63  ? 331 SER D O   1 
ATOM   8207 C  CB  . SER D 2 161 ? -59.584 -18.664 39.837  1   27.84  ? 331 SER D CB  1 
ATOM   8208 O  OG  . SER D 2 161 ? -59.714 -17.503 40.636  1   29.51  ? 331 SER D OG  1 
ATOM   8209 N  N   . LEU D 2 162 ? -59.359 -20.366 37.182  1   33.37  ? 332 LEU D N   1 
ATOM   8210 C  CA  . LEU D 2 162 ? -58.936 -21.624 36.591  1   34.16  ? 332 LEU D CA  1 
ATOM   8211 C  C   . LEU D 2 162 ? -57.967 -21.356 35.44   1   33.8   ? 332 LEU D C   1 
ATOM   8212 O  O   . LEU D 2 162 ? -56.959 -22.047 35.312  1   35.78  ? 332 LEU D O   1 
ATOM   8213 C  CB  . LEU D 2 162 ? -60.131 -22.47  36.127  1   34.18  ? 332 LEU D CB  1 
ATOM   8214 C  CG  . LEU D 2 162 ? -59.762 -23.828 35.522  1   36.48  ? 332 LEU D CG  1 
ATOM   8215 C  CD1 . LEU D 2 162 ? -58.869 -24.646 36.437  1   36.76  ? 332 LEU D CD1 1 
ATOM   8216 C  CD2 . LEU D 2 162 ? -61.001 -24.652 35.212  1   39.57  ? 332 LEU D CD2 1 
ATOM   8217 N  N   . ALA D 2 163 ? -58.257 -20.331 34.629  1   32.84  ? 333 ALA D N   1 
ATOM   8218 C  CA  . ALA D 2 163 ? -57.37  -19.945 33.541  1   35.3   ? 333 ALA D CA  1 
ATOM   8219 C  C   . ALA D 2 163 ? -55.989 -19.498 34.027  1   36.28  ? 333 ALA D C   1 
ATOM   8220 O  O   . ALA D 2 163 ? -54.978 -19.831 33.404  1   37.23  ? 333 ALA D O   1 
ATOM   8221 C  CB  . ALA D 2 163 ? -58.008 -18.849 32.696  1   35.08  ? 333 ALA D CB  1 
ATOM   8222 N  N   . MET D 2 164 ? -55.956 -18.736 35.131  1   34.67  ? 334 MET D N   1 
ATOM   8223 C  CA  . MET D 2 164 ? -54.707 -18.295 35.733  1   33.83  ? 334 MET D CA  1 
ATOM   8224 C  C   . MET D 2 164 ? -53.908 -19.51  36.199  1   31.32  ? 334 MET D C   1 
ATOM   8225 O  O   . MET D 2 164 ? -52.699 -19.572 35.985  1   32.5   ? 334 MET D O   1 
ATOM   8226 C  CB  . MET D 2 164 ? -54.964 -17.367 36.937  1   35.04  ? 334 MET D CB  1 
ATOM   8227 C  CG  . MET D 2 164 ? -55.444 -15.958 36.566  1   37.09  ? 334 MET D CG  1 
ATOM   8228 S  SD  . MET D 2 164 ? -54.226 -14.872 35.73   1   43.21  ? 334 MET D SD  1 
ATOM   8229 C  CE  . MET D 2 164 ? -54.113 -13.486 37.029  1   44.86  ? 334 MET D CE  1 
ATOM   8230 N  N   . PHE D 2 165 ? -54.603 -20.457 36.847  1   27.71  ? 335 PHE D N   1 
ATOM   8231 C  CA  . PHE D 2 165 ? -54.001 -21.685 37.343  1   28.23  ? 335 PHE D CA  1 
ATOM   8232 C  C   . PHE D 2 165 ? -53.282 -22.46  36.245  1   27.68  ? 335 PHE D C   1 
ATOM   8233 O  O   . PHE D 2 165 ? -52.129 -22.856 36.403  1   26.99  ? 335 PHE D O   1 
ATOM   8234 C  CB  . PHE D 2 165 ? -55.089 -22.574 37.958  1   30.13  ? 335 PHE D CB  1 
ATOM   8235 C  CG  . PHE D 2 165 ? -54.658 -23.974 38.335  1   32.07  ? 335 PHE D CG  1 
ATOM   8236 C  CD1 . PHE D 2 165 ? -53.657 -24.182 39.265  1   32.16  ? 335 PHE D CD1 1 
ATOM   8237 C  CD2 . PHE D 2 165 ? -55.279 -25.082 37.779  1   35.75  ? 335 PHE D CD2 1 
ATOM   8238 C  CE1 . PHE D 2 165 ? -53.274 -25.466 39.621  1   34.38  ? 335 PHE D CE1 1 
ATOM   8239 C  CE2 . PHE D 2 165 ? -54.894 -26.371 38.137  1   36.39  ? 335 PHE D CE2 1 
ATOM   8240 C  CZ  . PHE D 2 165 ? -53.897 -26.557 39.057  1   36.21  ? 335 PHE D CZ  1 
ATOM   8241 N  N   . LEU D 2 166 ? -53.994 -22.674 35.136  1   30.09  ? 336 LEU D N   1 
ATOM   8242 C  CA  . LEU D 2 166 ? -53.481 -23.449 34.02   1   31.41  ? 336 LEU D CA  1 
ATOM   8243 C  C   . LEU D 2 166 ? -52.301 -22.728 33.376  1   31.71  ? 336 LEU D C   1 
ATOM   8244 O  O   . LEU D 2 166 ? -51.303 -23.363 33.029  1   32.48  ? 336 LEU D O   1 
ATOM   8245 C  CB  . LEU D 2 166 ? -54.594 -23.685 32.999  1   31.06  ? 336 LEU D CB  1 
ATOM   8246 C  CG  . LEU D 2 166 ? -55.753 -24.541 33.474  1   31.98  ? 336 LEU D CG  1 
ATOM   8247 C  CD1 . LEU D 2 166 ? -56.832 -24.587 32.442  1   33.7   ? 336 LEU D CD1 1 
ATOM   8248 C  CD2 . LEU D 2 166 ? -55.313 -25.966 33.81   1   32.59  ? 336 LEU D CD2 1 
ATOM   8249 N  N   . GLY D 2 167 ? -52.425 -21.399 33.25   1   31.16  ? 337 GLY D N   1 
ATOM   8250 C  CA  . GLY D 2 167 ? -51.339 -20.562 32.768  1   29.13  ? 337 GLY D CA  1 
ATOM   8251 C  C   . GLY D 2 167 ? -50.071 -20.706 33.601  1   31.39  ? 337 GLY D C   1 
ATOM   8252 O  O   . GLY D 2 167 ? -48.976 -20.786 33.044  1   32.95  ? 337 GLY D O   1 
ATOM   8253 N  N   . GLU D 2 168 ? -50.233 -20.729 34.935  1   33.61  ? 338 GLU D N   1 
ATOM   8254 C  CA  . GLU D 2 168 ? -49.1   -20.875 35.839  1   33.42  ? 338 GLU D CA  1 
ATOM   8255 C  C   . GLU D 2 168 ? -48.455 -22.257 35.739  1   32.63  ? 338 GLU D C   1 
ATOM   8256 O  O   . GLU D 2 168 ? -47.232 -22.355 35.82   1   36.29  ? 338 GLU D O   1 
ATOM   8257 C  CB  . GLU D 2 168 ? -49.48  -20.585 37.304  1   31.98  ? 338 GLU D CB  1 
ATOM   8258 C  CG  . GLU D 2 168 ? -49.41  -19.122 37.669  1   33.55  ? 338 GLU D CG  1 
ATOM   8259 C  CD  . GLU D 2 168 ? -49.587 -18.817 39.147  1   35.27  ? 338 GLU D CD  1 
ATOM   8260 O  OE1 . GLU D 2 168 ? -48.986 -19.535 39.984  1   32.33  ? 338 GLU D OE1 1 
ATOM   8261 O  OE2 . GLU D 2 168 ? -50.291 -17.828 39.464  1   36.11  ? 338 GLU D OE2 1 
ATOM   8262 N  N   . LEU D 2 169 ? -49.262 -23.314 35.574  1   29.26  ? 339 LEU D N   1 
ATOM   8263 C  CA  . LEU D 2 169 ? -48.721 -24.657 35.417  1   28.03  ? 339 LEU D CA  1 
ATOM   8264 C  C   . LEU D 2 169 ? -47.744 -24.729 34.248  1   28.51  ? 339 LEU D C   1 
ATOM   8265 O  O   . LEU D 2 169 ? -46.733 -25.421 34.34   1   31.73  ? 339 LEU D O   1 
ATOM   8266 C  CB  . LEU D 2 169 ? -49.834 -25.713 35.195  1   28.77  ? 339 LEU D CB  1 
ATOM   8267 C  CG  . LEU D 2 169 ? -50.731 -26.065 36.393  1   28.23  ? 339 LEU D CG  1 
ATOM   8268 C  CD1 . LEU D 2 169 ? -51.676 -27.181 36.029  1   28.62  ? 339 LEU D CD1 1 
ATOM   8269 C  CD2 . LEU D 2 169 ? -49.909 -26.462 37.626  1   26.48  ? 339 LEU D CD2 1 
ATOM   8270 N  N   . SER D 2 170 ? -48.051 -24.011 33.159  1   29.05  ? 340 SER D N   1 
ATOM   8271 C  CA  . SER D 2 170 ? -47.215 -24.003 31.966  1   28.75  ? 340 SER D CA  1 
ATOM   8272 C  C   . SER D 2 170 ? -45.832 -23.394 32.202  1   30.55  ? 340 SER D C   1 
ATOM   8273 O  O   . SER D 2 170 ? -44.877 -23.729 31.501  1   35.52  ? 340 SER D O   1 
ATOM   8274 C  CB  . SER D 2 170 ? -47.91  -23.268 30.813  1   28.56  ? 340 SER D CB  1 
ATOM   8275 O  OG  . SER D 2 170 ? -47.791 -21.854 30.894  1   26.48  ? 340 SER D OG  1 
ATOM   8276 N  N   . LEU D 2 171 ? -45.725 -22.49  33.184  1   29.91  ? 341 LEU D N   1 
ATOM   8277 C  CA  . LEU D 2 171 ? -44.437 -21.93  33.566  1   28.44  ? 341 LEU D CA  1 
ATOM   8278 C  C   . LEU D 2 171 ? -43.422 -22.994 33.989  1   28.41  ? 341 LEU D C   1 
ATOM   8279 O  O   . LEU D 2 171 ? -42.225 -22.813 33.789  1   28.37  ? 341 LEU D O   1 
ATOM   8280 C  CB  . LEU D 2 171 ? -44.615 -20.935 34.717  1   27.63  ? 341 LEU D CB  1 
ATOM   8281 C  CG  . LEU D 2 171 ? -45.449 -19.69  34.438  1   25.7   ? 341 LEU D CG  1 
ATOM   8282 C  CD1 . LEU D 2 171 ? -45.554 -18.849 35.669  1   25.31  ? 341 LEU D CD1 1 
ATOM   8283 C  CD2 . LEU D 2 171 ? -44.859 -18.836 33.293  1   27.12  ? 341 LEU D CD2 1 
ATOM   8284 N  N   . ILE D 2 172 ? -43.912 -24.103 34.564  1   28.63  ? 342 ILE D N   1 
ATOM   8285 C  CA  . ILE D 2 172 ? -43.054 -25.108 35.17   1   28.27  ? 342 ILE D CA  1 
ATOM   8286 C  C   . ILE D 2 172 ? -42.279 -25.945 34.147  1   30.81  ? 342 ILE D C   1 
ATOM   8287 O  O   . ILE D 2 172 ? -41.116 -26.286 34.378  1   30.43  ? 342 ILE D O   1 
ATOM   8288 C  CB  . ILE D 2 172 ? -43.914 -26.024 36.092  1   26.75  ? 342 ILE D CB  1 
ATOM   8289 C  CG1 . ILE D 2 172 ? -44.619 -25.236 37.219  1   25.2   ? 342 ILE D CG1 1 
ATOM   8290 C  CG2 . ILE D 2 172 ? -43.08  -27.174 36.674  1   27.85  ? 342 ILE D CG2 1 
ATOM   8291 C  CD1 . ILE D 2 172 ? -43.714 -24.806 38.341  1   25.95  ? 342 ILE D CD1 1 
ATOM   8292 N  N   . ASP D 2 173 ? -42.937 -26.281 33.031  1   27.57  ? 343 ASP D N   1 
ATOM   8293 C  CA  . ASP D 2 173 ? -42.424 -27.263 32.093  1   29.86  ? 343 ASP D CA  1 
ATOM   8294 C  C   . ASP D 2 173 ? -42.007 -26.623 30.771  1   31.14  ? 343 ASP D C   1 
ATOM   8295 O  O   . ASP D 2 173 ? -42.843 -26.377 29.906  1   32.28  ? 343 ASP D O   1 
ATOM   8296 C  CB  . ASP D 2 173 ? -43.489 -28.352 31.863  1   29.57  ? 343 ASP D CB  1 
ATOM   8297 C  CG  . ASP D 2 173 ? -43.88  -29.033 33.15   1   30.65  ? 343 ASP D CG  1 
ATOM   8298 O  OD1 . ASP D 2 173 ? -42.975 -29.529 33.855  1   33.16  ? 343 ASP D OD1 1 
ATOM   8299 O  OD2 . ASP D 2 173 ? -45.081 -29.053 33.466  1   30.78  ? 343 ASP D OD2 1 
ATOM   8300 N  N   . ALA D 2 174 ? -40.698 -26.382 30.629  1   31.48  ? 344 ALA D N   1 
ATOM   8301 C  CA  . ALA D 2 174 ? -40.125 -25.798 29.424  1   33.64  ? 344 ALA D CA  1 
ATOM   8302 C  C   . ALA D 2 174 ? -40.418 -26.643 28.185  1   32.19  ? 344 ALA D C   1 
ATOM   8303 O  O   . ALA D 2 174 ? -40.623 -26.11  27.093  1   27.31  ? 344 ALA D O   1 
ATOM   8304 C  CB  . ALA D 2 174 ? -38.627 -25.637 29.586  1   34.99  ? 344 ALA D CB  1 
ATOM   8305 N  N   . ASP D 2 175 ? -40.403 -27.965 28.369  1   29.8   ? 345 ASP D N   1 
ATOM   8306 C  CA  . ASP D 2 175 ? -40.926 -28.881 27.375  1   31.3   ? 345 ASP D CA  1 
ATOM   8307 C  C   . ASP D 2 175 ? -42.313 -29.325 27.833  1   30.89  ? 345 ASP D C   1 
ATOM   8308 O  O   . ASP D 2 175 ? -42.41  -30.062 28.807  1   28.31  ? 345 ASP D O   1 
ATOM   8309 C  CB  . ASP D 2 175 ? -39.981 -30.084 27.207  1   31.97  ? 345 ASP D CB  1 
ATOM   8310 C  CG  . ASP D 2 175 ? -40.475 -31.202 26.295  1   31.63  ? 345 ASP D CG  1 
ATOM   8311 O  OD1 . ASP D 2 175 ? -41.576 -31.072 25.73   1   31.93  ? 345 ASP D OD1 1 
ATOM   8312 O  OD2 . ASP D 2 175 ? -39.769 -32.207 26.163  1   32.96  ? 345 ASP D OD2 1 
ATOM   8313 N  N   . PRO D 2 176 ? -43.419 -28.977 27.128  1   32.56  ? 346 PRO D N   1 
ATOM   8314 C  CA  . PRO D 2 176 ? -43.372 -28.328 25.812  1   31.87  ? 346 PRO D CA  1 
ATOM   8315 C  C   . PRO D 2 176 ? -43.574 -26.813 25.707  1   30.35  ? 346 PRO D C   1 
ATOM   8316 O  O   . PRO D 2 176 ? -43.529 -26.27  24.609  1   30.8   ? 346 PRO D O   1 
ATOM   8317 C  CB  . PRO D 2 176 ? -44.549 -29.008 25.104  1   31.33  ? 346 PRO D CB  1 
ATOM   8318 C  CG  . PRO D 2 176 ? -45.586 -29.195 26.216  1   31.36  ? 346 PRO D CG  1 
ATOM   8319 C  CD  . PRO D 2 176 ? -44.803 -29.296 27.531  1   31.02  ? 346 PRO D CD  1 
ATOM   8320 N  N   . TYR D 2 177 ? -43.785 -26.11  26.823  1   30.89  ? 347 TYR D N   1 
ATOM   8321 C  CA  . TYR D 2 177 ? -44.395 -24.791 26.733  1   30.12  ? 347 TYR D CA  1 
ATOM   8322 C  C   . TYR D 2 177 ? -43.497 -23.674 26.194  1   31.62  ? 347 TYR D C   1 
ATOM   8323 O  O   . TYR D 2 177 ? -44.013 -22.648 25.761  1   31.37  ? 347 TYR D O   1 
ATOM   8324 C  CB  . TYR D 2 177 ? -45.072 -24.425 28.083  1   29.88  ? 347 TYR D CB  1 
ATOM   8325 C  CG  . TYR D 2 177 ? -46.226 -25.368 28.34   1   31.86  ? 347 TYR D CG  1 
ATOM   8326 C  CD1 . TYR D 2 177 ? -47.347 -25.367 27.518  1   31.65  ? 347 TYR D CD1 1 
ATOM   8327 C  CD2 . TYR D 2 177 ? -46.155 -26.33  29.338  1   31.75  ? 347 TYR D CD2 1 
ATOM   8328 C  CE1 . TYR D 2 177 ? -48.38  -26.277 27.703  1   34.62  ? 347 TYR D CE1 1 
ATOM   8329 C  CE2 . TYR D 2 177 ? -47.191 -27.24  29.54   1   32.68  ? 347 TYR D CE2 1 
ATOM   8330 C  CZ  . TYR D 2 177 ? -48.298 -27.214 28.713  1   32.02  ? 347 TYR D CZ  1 
ATOM   8331 O  OH  . TYR D 2 177 ? -49.317 -28.103 28.898  1   27.1   ? 347 TYR D OH  1 
ATOM   8332 N  N   . LEU D 2 178 ? -42.173 -23.876 26.154  1   34.85  ? 348 LEU D N   1 
ATOM   8333 C  CA  . LEU D 2 178 ? -41.294 -22.914 25.499  1   35.02  ? 348 LEU D CA  1 
ATOM   8334 C  C   . LEU D 2 178 ? -41.595 -22.747 24.005  1   34.17  ? 348 LEU D C   1 
ATOM   8335 O  O   . LEU D 2 178 ? -41.266 -21.721 23.418  1   31.47  ? 348 LEU D O   1 
ATOM   8336 C  CB  . LEU D 2 178 ? -39.817 -23.303 25.643  1   36.94  ? 348 LEU D CB  1 
ATOM   8337 C  CG  . LEU D 2 178 ? -39.14  -22.971 26.961  1   41.97  ? 348 LEU D CG  1 
ATOM   8338 C  CD1 . LEU D 2 178 ? -37.656 -23.287 26.892  1   46.13  ? 348 LEU D CD1 1 
ATOM   8339 C  CD2 . LEU D 2 178 ? -39.302 -21.523 27.331  1   38.34  ? 348 LEU D CD2 1 
ATOM   8340 N  N   . LYS D 2 179 ? -42.225 -23.742 23.374  1   35.72  ? 349 LYS D N   1 
ATOM   8341 C  CA  . LYS D 2 179 ? -42.547 -23.606 21.962  1   38.52  ? 349 LYS D CA  1 
ATOM   8342 C  C   . LYS D 2 179 ? -43.769 -22.723 21.701  1   37.45  ? 349 LYS D C   1 
ATOM   8343 O  O   . LYS D 2 179 ? -44.005 -22.342 20.558  1   39.43  ? 349 LYS D O   1 
ATOM   8344 C  CB  . LYS D 2 179 ? -42.729 -24.98  21.288  1   37.31  ? 349 LYS D CB  1 
ATOM   8345 C  CG  . LYS D 2 179 ? -44.051 -25.648 21.539  1   40.67  ? 349 LYS D CG  1 
ATOM   8346 C  CD  . LYS D 2 179 ? -44.136 -27.033 20.895  1   42.2   ? 349 LYS D CD  1 
ATOM   8347 C  CE  . LYS D 2 179 ? -43.23  -28.051 21.528  1   41.24  ? 349 LYS D CE  1 
ATOM   8348 N  NZ  . LYS D 2 179 ? -43.46  -29.386 20.927  1   43.02  ? 349 LYS D NZ  1 
ATOM   8349 N  N   . TYR D 2 180 ? -44.534 -22.384 22.749  1   32.3   ? 350 TYR D N   1 
ATOM   8350 C  CA  . TYR D 2 180 ? -45.734 -21.577 22.583  1   30.32  ? 350 TYR D CA  1 
ATOM   8351 C  C   . TYR D 2 180 ? -45.553 -20.153 23.109  1   29.55  ? 350 TYR D C   1 
ATOM   8352 O  O   . TYR D 2 180 ? -44.927 -19.943 24.145  1   30.98  ? 350 TYR D O   1 
ATOM   8353 C  CB  . TYR D 2 180 ? -46.917 -22.242 23.293  1   28.81  ? 350 TYR D CB  1 
ATOM   8354 C  CG  . TYR D 2 180 ? -47.203 -23.656 22.826  1   26.19  ? 350 TYR D CG  1 
ATOM   8355 C  CD1 . TYR D 2 180 ? -47.618 -23.909 21.525  1   24.78  ? 350 TYR D CD1 1 
ATOM   8356 C  CD2 . TYR D 2 180 ? -47.079 -24.739 23.692  1   23.63  ? 350 TYR D CD2 1 
ATOM   8357 C  CE1 . TYR D 2 180 ? -47.891 -25.199 21.094  1   24.75  ? 350 TYR D CE1 1 
ATOM   8358 C  CE2 . TYR D 2 180 ? -47.357 -26.037 23.271  1   23.37  ? 350 TYR D CE2 1 
ATOM   8359 C  CZ  . TYR D 2 180 ? -47.762 -26.262 21.971  1   23.99  ? 350 TYR D CZ  1 
ATOM   8360 O  OH  . TYR D 2 180 ? -48.033 -27.537 21.527  1   24.56  ? 350 TYR D OH  1 
ATOM   8361 N  N   . LEU D 2 181 ? -46.102 -19.181 22.37   1   27.53  ? 351 LEU D N   1 
ATOM   8362 C  CA  . LEU D 2 181 ? -46.111 -17.787 22.775  1   29.01  ? 351 LEU D CA  1 
ATOM   8363 C  C   . LEU D 2 181 ? -47.113 -17.539 23.901  1   30.27  ? 351 LEU D C   1 
ATOM   8364 O  O   . LEU D 2 181 ? -48.135 -18.211 23.988  1   28.93  ? 351 LEU D O   1 
ATOM   8365 C  CB  . LEU D 2 181 ? -46.477 -16.891 21.582  1   30.17  ? 351 LEU D CB  1 
ATOM   8366 C  CG  . LEU D 2 181 ? -45.447 -16.807 20.454  1   30.6   ? 351 LEU D CG  1 
ATOM   8367 C  CD1 . LEU D 2 181 ? -46.008 -16.104 19.236  1   30.2   ? 351 LEU D CD1 1 
ATOM   8368 C  CD2 . LEU D 2 181 ? -44.219 -16.068 20.897  1   34.12  ? 351 LEU D CD2 1 
ATOM   8369 N  N   . PRO D 2 182 ? -46.865 -16.553 24.792  1   29.24  ? 352 PRO D N   1 
ATOM   8370 C  CA  . PRO D 2 182 ? -47.801 -16.25  25.877  1   29.84  ? 352 PRO D CA  1 
ATOM   8371 C  C   . PRO D 2 182 ? -49.264 -16.13  25.457  1   31.95  ? 352 PRO D C   1 
ATOM   8372 O  O   . PRO D 2 182 ? -50.15  -16.638 26.142  1   33.06  ? 352 PRO D O   1 
ATOM   8373 C  CB  . PRO D 2 182 ? -47.274 -14.919 26.419  1   31.31  ? 352 PRO D CB  1 
ATOM   8374 C  CG  . PRO D 2 182 ? -45.787 -14.956 26.11   1   30.69  ? 352 PRO D CG  1 
ATOM   8375 C  CD  . PRO D 2 182 ? -45.657 -15.713 24.812  1   29.63  ? 352 PRO D CD  1 
ATOM   8376 N  N   . SER D 2 183 ? -49.505 -15.46  24.324  1   30.91  ? 353 SER D N   1 
ATOM   8377 C  CA  . SER D 2 183 ? -50.854 -15.21  23.849  1   29.07  ? 353 SER D CA  1 
ATOM   8378 C  C   . SER D 2 183 ? -51.585 -16.492 23.458  1   29.23  ? 353 SER D C   1 
ATOM   8379 O  O   . SER D 2 183 ? -52.81  -16.555 23.561  1   29.7   ? 353 SER D O   1 
ATOM   8380 C  CB  . SER D 2 183 ? -50.843 -14.235 22.673  1   29.12  ? 353 SER D CB  1 
ATOM   8381 O  OG  . SER D 2 183 ? -50.294 -14.81  21.502  1   30.14  ? 353 SER D OG  1 
ATOM   8382 N  N   . VAL D 2 184 ? -50.825 -17.493 22.992  1   29.23  ? 354 VAL D N   1 
ATOM   8383 C  CA  . VAL D 2 184 ? -51.367 -18.801 22.649  1   27.08  ? 354 VAL D CA  1 
ATOM   8384 C  C   . VAL D 2 184 ? -51.661 -19.643 23.892  1   26.34  ? 354 VAL D C   1 
ATOM   8385 O  O   . VAL D 2 184 ? -52.728 -20.249 23.984  1   24.02  ? 354 VAL D O   1 
ATOM   8386 C  CB  . VAL D 2 184 ? -50.431 -19.566 21.681  1   27.82  ? 354 VAL D CB  1 
ATOM   8387 C  CG1 . VAL D 2 184 ? -50.887 -21.008 21.493  1   27.19  ? 354 VAL D CG1 1 
ATOM   8388 C  CG2 . VAL D 2 184 ? -50.318 -18.86  20.334  1   30.01  ? 354 VAL D CG2 1 
ATOM   8389 N  N   . ILE D 2 185 ? -50.717 -19.691 24.846  1   26.36  ? 355 ILE D N   1 
ATOM   8390 C  CA  . ILE D 2 185 ? -50.958 -20.4   26.093  1   26.61  ? 355 ILE D CA  1 
ATOM   8391 C  C   . ILE D 2 185 ? -52.174 -19.802 26.797  1   26.82  ? 355 ILE D C   1 
ATOM   8392 O  O   . ILE D 2 185 ? -53.007 -20.536 27.323  1   27.42  ? 355 ILE D O   1 
ATOM   8393 C  CB  . ILE D 2 185 ? -49.725 -20.413 27.007  1   27.33  ? 355 ILE D CB  1 
ATOM   8394 C  CG1 . ILE D 2 185 ? -48.586 -21.237 26.388  1   27.89  ? 355 ILE D CG1 1 
ATOM   8395 C  CG2 . ILE D 2 185 ? -50.075 -20.929 28.4    1   29.01  ? 355 ILE D CG2 1 
ATOM   8396 C  CD1 . ILE D 2 185 ? -47.278 -21.096 27.092  1   27.94  ? 355 ILE D CD1 1 
ATOM   8397 N  N   . ALA D 2 186 ? -52.265 -18.466 26.796  1   27.09  ? 356 ALA D N   1 
ATOM   8398 C  CA  . ALA D 2 186 ? -53.366 -17.77  27.443  1   26.08  ? 356 ALA D CA  1 
ATOM   8399 C  C   . ALA D 2 186 ? -54.701 -18.159 26.809  1   26.56  ? 356 ALA D C   1 
ATOM   8400 O  O   . ALA D 2 186 ? -55.681 -18.395 27.518  1   25.99  ? 356 ALA D O   1 
ATOM   8401 C  CB  . ALA D 2 186 ? -53.161 -16.269 27.359  1   25.57  ? 356 ALA D CB  1 
ATOM   8402 N  N   . ALA D 2 187 ? -54.721 -18.225 25.471  1   26.09  ? 357 ALA D N   1 
ATOM   8403 C  CA  . ALA D 2 187 ? -55.913 -18.625 24.74   1   27.36  ? 357 ALA D CA  1 
ATOM   8404 C  C   . ALA D 2 187 ? -56.318 -20.051 25.105  1   27.44  ? 357 ALA D C   1 
ATOM   8405 O  O   . ALA D 2 187 ? -57.476 -20.305 25.406  1   25.59  ? 357 ALA D O   1 
ATOM   8406 C  CB  . ALA D 2 187 ? -55.685 -18.515 23.241  1   27.86  ? 357 ALA D CB  1 
ATOM   8407 N  N   . ALA D 2 188 ? -55.349 -20.972 25.093  1   30.24  ? 358 ALA D N   1 
ATOM   8408 C  CA  . ALA D 2 188 ? -55.621 -22.365 25.413  1   32.39  ? 358 ALA D CA  1 
ATOM   8409 C  C   . ALA D 2 188 ? -56.158 -22.489 26.836  1   32.77  ? 358 ALA D C   1 
ATOM   8410 O  O   . ALA D 2 188 ? -57.142 -23.187 27.073  1   37.19  ? 358 ALA D O   1 
ATOM   8411 C  CB  . ALA D 2 188 ? -54.373 -23.221 25.234  1   31.72  ? 358 ALA D CB  1 
ATOM   8412 N  N   . ALA D 2 189 ? -55.499 -21.797 27.764  1   33.16  ? 359 ALA D N   1 
ATOM   8413 C  CA  . ALA D 2 189 ? -55.905 -21.773 29.158  1   33.41  ? 359 ALA D CA  1 
ATOM   8414 C  C   . ALA D 2 189 ? -57.322 -21.223 29.33   1   32.46  ? 359 ALA D C   1 
ATOM   8415 O  O   . ALA D 2 189 ? -58.123 -21.771 30.077  1   32.19  ? 359 ALA D O   1 
ATOM   8416 C  CB  . ALA D 2 189 ? -54.923 -20.932 29.95   1   33.16  ? 359 ALA D CB  1 
ATOM   8417 N  N   . PHE D 2 190 ? -57.625 -20.127 28.632  1   31.94  ? 360 PHE D N   1 
ATOM   8418 C  CA  . PHE D 2 190 ? -58.933 -19.506 28.737  1   31.42  ? 360 PHE D CA  1 
ATOM   8419 C  C   . PHE D 2 190 ? -60.029 -20.438 28.217  1   30.9   ? 360 PHE D C   1 
ATOM   8420 O  O   . PHE D 2 190 ? -61.058 -20.597 28.868  1   28.21  ? 360 PHE D O   1 
ATOM   8421 C  CB  . PHE D 2 190 ? -58.956 -18.162 27.995  1   31.81  ? 360 PHE D CB  1 
ATOM   8422 C  CG  . PHE D 2 190 ? -60.283 -17.458 28.08   1   33.37  ? 360 PHE D CG  1 
ATOM   8423 C  CD1 . PHE D 2 190 ? -60.798 -17.068 29.297  1   31.81  ? 360 PHE D CD1 1 
ATOM   8424 C  CD2 . PHE D 2 190 ? -61.037 -17.226 26.944  1   36.68  ? 360 PHE D CD2 1 
ATOM   8425 C  CE1 . PHE D 2 190 ? -62.028 -16.428 29.376  1   33.13  ? 360 PHE D CE1 1 
ATOM   8426 C  CE2 . PHE D 2 190 ? -62.268 -16.584 27.026  1   37.09  ? 360 PHE D CE2 1 
ATOM   8427 C  CZ  . PHE D 2 190 ? -62.754 -16.185 28.243  1   35.37  ? 360 PHE D CZ  1 
ATOM   8428 N  N   . HIS D 2 191 ? -59.799 -21.058 27.053  1   29.59  ? 361 HIS D N   1 
ATOM   8429 C  CA  . HIS D 2 191 ? -60.765 -21.983 26.482  1   31.83  ? 361 HIS D CA  1 
ATOM   8430 C  C   . HIS D 2 191 ? -61.008 -23.185 27.389  1   32.13  ? 361 HIS D C   1 
ATOM   8431 O  O   . HIS D 2 191 ? -62.144 -23.608 27.583  1   33.43  ? 361 HIS D O   1 
ATOM   8432 C  CB  . HIS D 2 191 ? -60.331 -22.534 25.115  1   32.12  ? 361 HIS D CB  1 
ATOM   8433 C  CG  . HIS D 2 191 ? -61.202 -23.678 24.689  1   31.47  ? 361 HIS D CG  1 
ATOM   8434 N  ND1 . HIS D 2 191 ? -62.497 -23.472 24.246  1   32.89  ? 361 HIS D ND1 1 
ATOM   8435 C  CD2 . HIS D 2 191 ? -60.965 -25.007 24.719  1   30.74  ? 361 HIS D CD2 1 
ATOM   8436 C  CE1 . HIS D 2 191 ? -62.993 -24.674 23.978  1   30.82  ? 361 HIS D CE1 1 
ATOM   8437 N  NE2 . HIS D 2 191 ? -62.108 -25.627 24.263  1   29.45  ? 361 HIS D NE2 1 
ATOM   8438 N  N   . LEU D 2 192 ? -59.913 -23.753 27.893  1   32.87  ? 362 LEU D N   1 
ATOM   8439 C  CA  . LEU D 2 192 ? -59.979 -24.951 28.706  1   32.83  ? 362 LEU D CA  1 
ATOM   8440 C  C   . LEU D 2 192 ? -60.722 -24.653 30.007  1   32.08  ? 362 LEU D C   1 
ATOM   8441 O  O   . LEU D 2 192 ? -61.566 -25.438 30.435  1   31.22  ? 362 LEU D O   1 
ATOM   8442 C  CB  . LEU D 2 192 ? -58.555 -25.441 28.941  1   33.31  ? 362 LEU D CB  1 
ATOM   8443 C  CG  . LEU D 2 192 ? -58.392 -26.761 29.633  1   34.05  ? 362 LEU D CG  1 
ATOM   8444 C  CD1 . LEU D 2 192 ? -59.274 -27.844 29.004  1   34.52  ? 362 LEU D CD1 1 
ATOM   8445 C  CD2 . LEU D 2 192 ? -56.91  -27.18  29.606  1   34.3   ? 362 LEU D CD2 1 
ATOM   8446 N  N   . ALA D 2 193 ? -60.415 -23.497 30.605  1   31.04  ? 363 ALA D N   1 
ATOM   8447 C  CA  . ALA D 2 193 ? -61.079 -23.044 31.817  1   32.12  ? 363 ALA D CA  1 
ATOM   8448 C  C   . ALA D 2 193 ? -62.571 -22.821 31.601  1   33.07  ? 363 ALA D C   1 
ATOM   8449 O  O   . ALA D 2 193 ? -63.394 -23.293 32.381  1   32.8   ? 363 ALA D O   1 
ATOM   8450 C  CB  . ALA D 2 193 ? -60.437 -21.761 32.321  1   32.16  ? 363 ALA D CB  1 
ATOM   8451 N  N   . LEU D 2 194 ? -62.89  -22.079 30.537  1   35.31  ? 364 LEU D N   1 
ATOM   8452 C  CA  . LEU D 2 194 ? -64.257 -21.788 30.142  1   36.41  ? 364 LEU D CA  1 
ATOM   8453 C  C   . LEU D 2 194 ? -65.041 -23.079 29.913  1   38.37  ? 364 LEU D C   1 
ATOM   8454 O  O   . LEU D 2 194 ? -66.139 -23.254 30.443  1   40     ? 364 LEU D O   1 
ATOM   8455 C  CB  . LEU D 2 194 ? -64.215 -20.949 28.86   1   38.23  ? 364 LEU D CB  1 
ATOM   8456 C  CG  . LEU D 2 194 ? -65.477 -20.232 28.471  1   42.27  ? 364 LEU D CG  1 
ATOM   8457 C  CD1 . LEU D 2 194 ? -65.696 -19.016 29.367  1   40.6   ? 364 LEU D CD1 1 
ATOM   8458 C  CD2 . LEU D 2 194 ? -65.41  -19.802 27.004  1   43.97  ? 364 LEU D CD2 1 
ATOM   8459 N  N   . TYR D 2 195 ? -64.446 -23.994 29.138  1   36.92  ? 365 TYR D N   1 
ATOM   8460 C  CA  . TYR D 2 195 ? -65.058 -25.28  28.848  1   35.34  ? 365 TYR D CA  1 
ATOM   8461 C  C   . TYR D 2 195 ? -65.291 -26.101 30.113  1   33.65  ? 365 TYR D C   1 
ATOM   8462 O  O   . TYR D 2 195 ? -66.36  -26.676 30.275  1   32.23  ? 365 TYR D O   1 
ATOM   8463 C  CB  . TYR D 2 195 ? -64.196 -26.056 27.827  1   36.28  ? 365 TYR D CB  1 
ATOM   8464 C  CG  . TYR D 2 195 ? -64.799 -27.368 27.385  1   35.66  ? 365 TYR D CG  1 
ATOM   8465 C  CD1 . TYR D 2 195 ? -64.638 -28.52  28.141  1   35.8   ? 365 TYR D CD1 1 
ATOM   8466 C  CD2 . TYR D 2 195 ? -65.547 -27.454 26.217  1   37.51  ? 365 TYR D CD2 1 
ATOM   8467 C  CE1 . TYR D 2 195 ? -65.198 -29.732 27.74   1   38.87  ? 365 TYR D CE1 1 
ATOM   8468 C  CE2 . TYR D 2 195 ? -66.126 -28.652 25.814  1   38.87  ? 365 TYR D CE2 1 
ATOM   8469 C  CZ  . TYR D 2 195 ? -65.942 -29.792 26.571  1   38.65  ? 365 TYR D CZ  1 
ATOM   8470 O  OH  . TYR D 2 195 ? -66.516 -30.966 26.155  1   38.55  ? 365 TYR D OH  1 
ATOM   8471 N  N   . THR D 2 196 ? -64.318 -26.11  31.021  1   33.86  ? 366 THR D N   1 
ATOM   8472 C  CA  . THR D 2 196 ? -64.402 -26.95  32.234  1   32.86  ? 366 THR D CA  1 
ATOM   8473 C  C   . THR D 2 196 ? -65.455 -26.438 33.197  1   32.38  ? 366 THR D C   1 
ATOM   8474 O  O   . THR D 2 196 ? -66.036 -27.266 33.923  1   30.93  ? 366 THR D O   1 
ATOM   8475 C  CB  . THR D 2 196 ? -63.017 -26.998 32.875  1   33.69  ? 366 THR D CB  1 
ATOM   8476 O  OG1 . THR D 2 196 ? -62.144 -27.465 31.853  1   31.5   ? 366 THR D OG1 1 
ATOM   8477 C  CG2 . THR D 2 196 ? -62.948 -27.91  34.086  1   33.97  ? 366 THR D CG2 1 
ATOM   8478 N  N   . VAL D 2 197 ? -65.73  -25.137 33.205  1   33.69  ? 367 VAL D N   1 
ATOM   8479 C  CA  . VAL D 2 197 ? -66.672 -24.577 34.218  1   35.42  ? 367 VAL D CA  1 
ATOM   8480 C  C   . VAL D 2 197 ? -68.048 -24.327 33.585  1   37.14  ? 367 VAL D C   1 
ATOM   8481 O  O   . VAL D 2 197 ? -69.06  -24.598 34.259  1   34.58  ? 367 VAL D O   1 
ATOM   8482 C  CB  . VAL D 2 197 ? -66.083 -23.285 34.813  1   35.99  ? 367 VAL D CB  1 
ATOM   8483 C  CG1 . VAL D 2 197 ? -67.01  -22.635 35.832  1   35.45  ? 367 VAL D CG1 1 
ATOM   8484 C  CG2 . VAL D 2 197 ? -64.704 -23.512 35.417  1   36.57  ? 367 VAL D CG2 1 
ATOM   8485 N  N   . THR D 2 198 ? -68.086 -23.866 32.335  1   40.32  ? 368 THR D N   1 
ATOM   8486 C  CA  . THR D 2 198 ? -69.371 -23.491 31.707  1   39.97  ? 368 THR D CA  1 
ATOM   8487 C  C   . THR D 2 198 ? -69.752 -24.444 30.597  1   39.17  ? 368 THR D C   1 
ATOM   8488 O  O   . THR D 2 198 ? -70.946 -24.473 30.248  1   38.77  ? 368 THR D O   1 
ATOM   8489 C  CB  . THR D 2 198 ? -69.24  -22.073 31.161  1   40.75  ? 368 THR D CB  1 
ATOM   8490 O  OG1 . THR D 2 198 ? -68.437 -22.211 29.995  1   41.81  ? 368 THR D OG1 1 
ATOM   8491 C  CG2 . THR D 2 198 ? -68.585 -21.127 32.15   1   40.26  ? 368 THR D CG2 1 
ATOM   8492 N  N   . GLY D 2 199 ? -68.795 -25.169 30.023  1   37.74  ? 369 GLY D N   1 
ATOM   8493 C  CA  . GLY D 2 199 ? -69.114 -26.016 28.862  1   36.62  ? 369 GLY D CA  1 
ATOM   8494 C  C   . GLY D 2 199 ? -69.001 -25.213 27.589  1   36.92  ? 369 GLY D C   1 
ATOM   8495 O  O   . GLY D 2 199 ? -69.044 -25.817 26.502  1   34.13  ? 369 GLY D O   1 
ATOM   8496 N  N   . GLN D 2 200 ? -68.841 -23.896 27.715  1   39.64  ? 370 GLN D N   1 
ATOM   8497 C  CA  . GLN D 2 200 ? -68.787 -23.019 26.519  1   41.29  ? 370 GLN D CA  1 
ATOM   8498 C  C   . GLN D 2 200 ? -67.381 -23.066 25.919  1   40.18  ? 370 GLN D C   1 
ATOM   8499 O  O   . GLN D 2 200 ? -66.469 -23.588 26.573  1   40.88  ? 370 GLN D O   1 
ATOM   8500 C  CB  . GLN D 2 200 ? -69.157 -21.574 26.85   1   43.57  ? 370 GLN D CB  1 
ATOM   8501 C  CG  . GLN D 2 200 ? -70.611 -21.378 27.26   1   43     ? 370 GLN D CG  1 
ATOM   8502 C  CD  . GLN D 2 200 ? -70.915 -19.95  27.648  1   44.21  ? 370 GLN D CD  1 
ATOM   8503 O  OE1 . GLN D 2 200 ? -70.029 -19.194 28.059  1   44.79  ? 370 GLN D OE1 1 
ATOM   8504 N  NE2 . GLN D 2 200 ? -72.179 -19.571 27.532  1   41.38  ? 370 GLN D NE2 1 
ATOM   8505 N  N   . SER D 2 201 ? -67.22  -22.509 24.725  1   38.96  ? 371 SER D N   1 
ATOM   8506 C  CA  . SER D 2 201 ? -65.909 -22.617 24.045  1   38.94  ? 371 SER D CA  1 
ATOM   8507 C  C   . SER D 2 201 ? -65.345 -21.257 23.618  1   38.79  ? 371 SER D C   1 
ATOM   8508 O  O   . SER D 2 201 ? -66.102 -20.272 23.631  1   39.31  ? 371 SER D O   1 
ATOM   8509 C  CB  . SER D 2 201 ? -66.02  -23.543 22.862  1   37.1   ? 371 SER D CB  1 
ATOM   8510 O  OG  . SER D 2 201 ? -66.307 -24.868 23.286  1   37.94  ? 371 SER D OG  1 
ATOM   8511 N  N   . TRP D 2 202 ? -64.056 -21.21  23.296  1   37.54  ? 372 TRP D N   1 
ATOM   8512 C  CA  . TRP D 2 202 ? -63.398 -20.025 22.769  1   38.67  ? 372 TRP D CA  1 
ATOM   8513 C  C   . TRP D 2 202 ? -64.375 -19.191 21.944  1   37.09  ? 372 TRP D C   1 
ATOM   8514 O  O   . TRP D 2 202 ? -64.847 -19.652 20.909  1   35.95  ? 372 TRP D O   1 
ATOM   8515 C  CB  . TRP D 2 202 ? -62.189 -20.485 21.921  1   38.73  ? 372 TRP D CB  1 
ATOM   8516 C  CG  . TRP D 2 202 ? -61.33  -19.414 21.325  1   36.73  ? 372 TRP D CG  1 
ATOM   8517 C  CD1 . TRP D 2 202 ? -61.189 -19.129 20      1   35.42  ? 372 TRP D CD1 1 
ATOM   8518 C  CD2 . TRP D 2 202 ? -60.433 -18.538 22.023  1   36.73  ? 372 TRP D CD2 1 
ATOM   8519 N  NE1 . TRP D 2 202 ? -60.281 -18.109 19.828  1   37.43  ? 372 TRP D NE1 1 
ATOM   8520 C  CE2 . TRP D 2 202 ? -59.808 -17.721 21.057  1   35.63  ? 372 TRP D CE2 1 
ATOM   8521 C  CE3 . TRP D 2 202 ? -60.11  -18.35  23.374  1   34.97  ? 372 TRP D CE3 1 
ATOM   8522 C  CZ2 . TRP D 2 202 ? -58.88  -16.743 21.4    1   31.97  ? 372 TRP D CZ2 1 
ATOM   8523 C  CZ3 . TRP D 2 202 ? -59.193 -17.372 23.707  1   32.42  ? 372 TRP D CZ3 1 
ATOM   8524 C  CH2 . TRP D 2 202 ? -58.599 -16.577 22.729  1   31.83  ? 372 TRP D CH2 1 
ATOM   8525 N  N   . PRO D 2 203 ? -64.736 -17.963 22.387  1   36.32  ? 373 PRO D N   1 
ATOM   8526 C  CA  . PRO D 2 203 ? -65.78  -17.184 21.715  1   35.59  ? 373 PRO D CA  1 
ATOM   8527 C  C   . PRO D 2 203 ? -65.341 -16.541 20.402  1   34.07  ? 373 PRO D C   1 
ATOM   8528 O  O   . PRO D 2 203 ? -64.177 -16.173 20.235  1   32.19  ? 373 PRO D O   1 
ATOM   8529 C  CB  . PRO D 2 203 ? -66.137 -16.114 22.752  1   35.48  ? 373 PRO D CB  1 
ATOM   8530 C  CG  . PRO D 2 203 ? -64.86  -15.93  23.541  1   35.13  ? 373 PRO D CG  1 
ATOM   8531 C  CD  . PRO D 2 203 ? -64.18  -17.278 23.566  1   35.23  ? 373 PRO D CD  1 
ATOM   8532 N  N   . GLU D 2 204 ? -66.315 -16.382 19.497  1   33.77  ? 374 GLU D N   1 
ATOM   8533 C  CA  . GLU D 2 204 ? -66.088 -15.822 18.175  1   33.88  ? 374 GLU D CA  1 
ATOM   8534 C  C   . GLU D 2 204 ? -65.446 -14.437 18.254  1   33.67  ? 374 GLU D C   1 
ATOM   8535 O  O   . GLU D 2 204 ? -64.616 -14.097 17.413  1   34.22  ? 374 GLU D O   1 
ATOM   8536 C  CB  . GLU D 2 204 ? -67.424 -15.788 17.405  1   33.16  ? 374 GLU D CB  1 
ATOM   8537 C  CG  . GLU D 2 204 ? -67.364 -15.25  15.982  1   34.58  ? 374 GLU D CG  1 
ATOM   8538 C  CD  . GLU D 2 204 ? -66.355 -15.924 15.078  1   36.08  ? 374 GLU D CD  1 
ATOM   8539 O  OE1 . GLU D 2 204 ? -66.411 -17.169 14.976  1   35.71  ? 374 GLU D OE1 1 
ATOM   8540 O  OE2 . GLU D 2 204 ? -65.515 -15.217 14.469  1   38     ? 374 GLU D OE2 1 
ATOM   8541 N  N   . SER D 2 205 ? -65.818 -13.657 19.279  1   31.49  ? 375 SER D N   1 
ATOM   8542 C  CA  . SER D 2 205 ? -65.298 -12.311 19.457  1   29.77  ? 375 SER D CA  1 
ATOM   8543 C  C   . SER D 2 205 ? -63.785 -12.284 19.688  1   30.96  ? 375 SER D C   1 
ATOM   8544 O  O   . SER D 2 205 ? -63.115 -11.315 19.324  1   28.98  ? 375 SER D O   1 
ATOM   8545 C  CB  . SER D 2 205 ? -66.025 -11.619 20.608  1   29.33  ? 375 SER D CB  1 
ATOM   8546 O  OG  . SER D 2 205 ? -65.641 -12.128 21.875  1   27.15  ? 375 SER D OG  1 
ATOM   8547 N  N   . LEU D 2 206 ? -63.257 -13.355 20.294  1   31.36  ? 376 LEU D N   1 
ATOM   8548 C  CA  . LEU D 2 206 ? -61.828 -13.497 20.524  1   32.14  ? 376 LEU D CA  1 
ATOM   8549 C  C   . LEU D 2 206 ? -61.108 -14.106 19.323  1   33.47  ? 376 LEU D C   1 
ATOM   8550 O  O   . LEU D 2 206 ? -59.906 -13.899 19.157  1   33.24  ? 376 LEU D O   1 
ATOM   8551 C  CB  . LEU D 2 206 ? -61.584 -14.342 21.776  1   31.96  ? 376 LEU D CB  1 
ATOM   8552 C  CG  . LEU D 2 206 ? -61.808 -13.583 23.091  1   33.52  ? 376 LEU D CG  1 
ATOM   8553 C  CD1 . LEU D 2 206 ? -61.677 -14.508 24.279  1   33.65  ? 376 LEU D CD1 1 
ATOM   8554 C  CD2 . LEU D 2 206 ? -60.819 -12.422 23.221  1   33.84  ? 376 LEU D CD2 1 
ATOM   8555 N  N   . VAL D 2 207 ? -61.848 -14.862 18.498  1   30.62  ? 377 VAL D N   1 
ATOM   8556 C  CA  . VAL D 2 207 ? -61.369 -15.233 17.179  1   30.27  ? 377 VAL D CA  1 
ATOM   8557 C  C   . VAL D 2 207 ? -61.093 -13.957 16.389  1   31.27  ? 377 VAL D C   1 
ATOM   8558 O  O   . VAL D 2 207 ? -60.037 -13.827 15.774  1   30.87  ? 377 VAL D O   1 
ATOM   8559 C  CB  . VAL D 2 207 ? -62.36  -16.168 16.422  1   31.06  ? 377 VAL D CB  1 
ATOM   8560 C  CG1 . VAL D 2 207 ? -61.931 -16.401 14.965  1   29.37  ? 377 VAL D CG1 1 
ATOM   8561 C  CG2 . VAL D 2 207 ? -62.536 -17.487 17.159  1   30.43  ? 377 VAL D CG2 1 
ATOM   8562 N  N   . GLN D 2 208 ? -62.047 -13.017 16.413  1   33.49  ? 378 GLN D N   1 
ATOM   8563 C  CA  . GLN D 2 208 ? -61.887 -11.774 15.674  1   35.71  ? 378 GLN D CA  1 
ATOM   8564 C  C   . GLN D 2 208 ? -60.714 -10.964 16.22   1   33.86  ? 378 GLN D C   1 
ATOM   8565 O  O   . GLN D 2 208 ? -59.942 -10.419 15.437  1   33.78  ? 378 GLN D O   1 
ATOM   8566 C  CB  . GLN D 2 208 ? -63.193 -10.945 15.629  1   36.73  ? 378 GLN D CB  1 
ATOM   8567 C  CG  . GLN D 2 208 ? -64.286 -11.585 14.751  1   39.43  ? 378 GLN D CG  1 
ATOM   8568 C  CD  . GLN D 2 208 ? -63.818 -11.853 13.327  1   41.96  ? 378 GLN D CD  1 
ATOM   8569 O  OE1 . GLN D 2 208 ? -63.738 -12.998 12.854  1   36.6   ? 378 GLN D OE1 1 
ATOM   8570 N  NE2 . GLN D 2 208 ? -63.445 -10.787 12.641  1   48.06  ? 378 GLN D NE2 1 
ATOM   8571 N  N   . LYS D 2 209 ? -60.562 -10.919 17.551  1   33.15  ? 379 LYS D N   1 
ATOM   8572 C  CA  . LYS D 2 209 ? -59.511 -10.133 18.178  1   32.31  ? 379 LYS D CA  1 
ATOM   8573 C  C   . LYS D 2 209 ? -58.124 -10.713 17.919  1   31.4   ? 379 LYS D C   1 
ATOM   8574 O  O   . LYS D 2 209 ? -57.203 -9.968  17.589  1   32.25  ? 379 LYS D O   1 
ATOM   8575 C  CB  . LYS D 2 209 ? -59.742 -10.031 19.697  1   34.05  ? 379 LYS D CB  1 
ATOM   8576 C  CG  . LYS D 2 209 ? -58.741 -9.144  20.454  1   35.29  ? 379 LYS D CG  1 
ATOM   8577 C  CD  . LYS D 2 209 ? -58.89  -9.293  21.976  1   36.65  ? 379 LYS D CD  1 
ATOM   8578 C  CE  . LYS D 2 209 ? -57.967 -8.394  22.778  1   34.86  ? 379 LYS D CE  1 
ATOM   8579 N  NZ  . LYS D 2 209 ? -58.381 -6.974  22.718  1   35.48  ? 379 LYS D NZ  1 
ATOM   8580 N  N   . THR D 2 210 ? -57.984 -12.034 18.091  1   29.77  ? 380 THR D N   1 
ATOM   8581 C  CA  . THR D 2 210 ? -56.678 -12.675 18.101  1   31.25  ? 380 THR D CA  1 
ATOM   8582 C  C   . THR D 2 210 ? -56.239 -13.306 16.78   1   32.66  ? 380 THR D C   1 
ATOM   8583 O  O   . THR D 2 210 ? -55.048 -13.507 16.564  1   32.29  ? 380 THR D O   1 
ATOM   8584 C  CB  . THR D 2 210 ? -56.618 -13.761 19.187  1   32.44  ? 380 THR D CB  1 
ATOM   8585 O  OG1 . THR D 2 210 ? -57.441 -14.886 18.804  1   35.05  ? 380 THR D OG1 1 
ATOM   8586 C  CG2 . THR D 2 210 ? -57.023 -13.213 20.559  1   32.35  ? 380 THR D CG2 1 
ATOM   8587 N  N   . GLY D 2 211 ? -57.201 -13.654 15.918  1   32     ? 381 GLY D N   1 
ATOM   8588 C  CA  . GLY D 2 211 ? -56.922 -14.483 14.755  1   30.54  ? 381 GLY D CA  1 
ATOM   8589 C  C   . GLY D 2 211 ? -56.806 -15.98  15.054  1   30.6   ? 381 GLY D C   1 
ATOM   8590 O  O   . GLY D 2 211 ? -56.723 -16.786 14.133  1   31.74  ? 381 GLY D O   1 
ATOM   8591 N  N   . TYR D 2 212 ? -56.815 -16.352 16.34   1   30.56  ? 382 TYR D N   1 
ATOM   8592 C  CA  . TYR D 2 212 ? -56.701 -17.743 16.744  1   31.66  ? 382 TYR D CA  1 
ATOM   8593 C  C   . TYR D 2 212 ? -58.055 -18.449 16.739  1   30.55  ? 382 TYR D C   1 
ATOM   8594 O  O   . TYR D 2 212 ? -59.023 -17.931 17.294  1   29.08  ? 382 TYR D O   1 
ATOM   8595 C  CB  . TYR D 2 212 ? -56.124 -17.858 18.169  1   31.63  ? 382 TYR D CB  1 
ATOM   8596 C  CG  . TYR D 2 212 ? -54.766 -17.238 18.397  1   31.26  ? 382 TYR D CG  1 
ATOM   8597 C  CD1 . TYR D 2 212 ? -53.84  -17.124 17.362  1   30.31  ? 382 TYR D CD1 1 
ATOM   8598 C  CD2 . TYR D 2 212 ? -54.406 -16.748 19.649  1   30.8   ? 382 TYR D CD2 1 
ATOM   8599 C  CE1 . TYR D 2 212 ? -52.584 -16.549 17.577  1   31.48  ? 382 TYR D CE1 1 
ATOM   8600 C  CE2 . TYR D 2 212 ? -53.163 -16.162 19.869  1   29.02  ? 382 TYR D CE2 1 
ATOM   8601 C  CZ  . TYR D 2 212 ? -52.252 -16.069 18.837  1   28.72  ? 382 TYR D CZ  1 
ATOM   8602 O  OH  . TYR D 2 212 ? -51.03  -15.496 19.084  1   27.08  ? 382 TYR D OH  1 
ATOM   8603 N  N   . THR D 2 213 ? -58.092 -19.647 16.136  1   29.06  ? 383 THR D N   1 
ATOM   8604 C  CA  . THR D 2 213 ? -59.254 -20.518 16.199  1   29.98  ? 383 THR D CA  1 
ATOM   8605 C  C   . THR D 2 213 ? -58.932 -21.731 17.064  1   29.96  ? 383 THR D C   1 
ATOM   8606 O  O   . THR D 2 213 ? -57.776 -21.959 17.396  1   29.87  ? 383 THR D O   1 
ATOM   8607 C  CB  . THR D 2 213 ? -59.645 -20.978 14.812  1   31.6   ? 383 THR D CB  1 
ATOM   8608 O  OG1 . THR D 2 213 ? -58.625 -21.846 14.341  1   32.05  ? 383 THR D OG1 1 
ATOM   8609 C  CG2 . THR D 2 213 ? -59.842 -19.819 13.838  1   32.15  ? 383 THR D CG2 1 
ATOM   8610 N  N   . LEU D 2 214 ? -59.947 -22.533 17.391  1   31.21  ? 384 LEU D N   1 
ATOM   8611 C  CA  . LEU D 2 214 ? -59.713 -23.78  18.105  1   32.56  ? 384 LEU D CA  1 
ATOM   8612 C  C   . LEU D 2 214 ? -58.79  -24.71  17.318  1   33.76  ? 384 LEU D C   1 
ATOM   8613 O  O   . LEU D 2 214 ? -58.051 -25.492 17.912  1   31.81  ? 384 LEU D O   1 
ATOM   8614 C  CB  . LEU D 2 214 ? -61.027 -24.498 18.421  1   31.9   ? 384 LEU D CB  1 
ATOM   8615 C  CG  . LEU D 2 214 ? -61.9   -23.855 19.496  1   32.43  ? 384 LEU D CG  1 
ATOM   8616 C  CD1 . LEU D 2 214 ? -63.018 -24.776 19.902  1   32.55  ? 384 LEU D CD1 1 
ATOM   8617 C  CD2 . LEU D 2 214 ? -61.097 -23.467 20.732  1   33.66  ? 384 LEU D CD2 1 
ATOM   8618 N  N   . GLU D 2 215 ? -58.822 -24.613 15.982  1   35.86  ? 385 GLU D N   1 
ATOM   8619 C  CA  . GLU D 2 215 ? -57.864 -25.323 15.147  1   38.04  ? 385 GLU D CA  1 
ATOM   8620 C  C   . GLU D 2 215 ? -56.434 -24.868 15.447  1   38.68  ? 385 GLU D C   1 
ATOM   8621 O  O   . GLU D 2 215 ? -55.572 -25.695 15.724  1   38.95  ? 385 GLU D O   1 
ATOM   8622 C  CB  . GLU D 2 215 ? -58.189 -25.13  13.663  1   40.24  ? 385 GLU D CB  1 
ATOM   8623 C  CG  . GLU D 2 215 ? -57.455 -26.098 12.757  1   44.63  ? 385 GLU D CG  1 
ATOM   8624 C  CD  . GLU D 2 215 ? -57.753 -25.885 11.291  1   47.47  ? 385 GLU D CD  1 
ATOM   8625 O  OE1 . GLU D 2 215 ? -57.692 -24.717 10.848  1   51.16  ? 385 GLU D OE1 1 
ATOM   8626 O  OE2 . GLU D 2 215 ? -58.038 -26.877 10.582  1   46.77  ? 385 GLU D OE2 1 
ATOM   8627 N  N   . THR D 2 216 ? -56.188 -23.552 15.404  1   36.39  ? 386 THR D N   1 
ATOM   8628 C  CA  . THR D 2 216 ? -54.86  -23.024 15.672  1   37.37  ? 386 THR D CA  1 
ATOM   8629 C  C   . THR D 2 216 ? -54.372 -23.387 17.075  1   36.48  ? 386 THR D C   1 
ATOM   8630 O  O   . THR D 2 216 ? -53.202 -23.715 17.243  1   35.53  ? 386 THR D O   1 
ATOM   8631 C  CB  . THR D 2 216 ? -54.785 -21.502 15.427  1   39.02  ? 386 THR D CB  1 
ATOM   8632 O  OG1 . THR D 2 216 ? -55.609 -20.812 16.362  1   42.58  ? 386 THR D OG1 1 
ATOM   8633 C  CG2 . THR D 2 216 ? -55.163 -21.121 13.986  1   37.79  ? 386 THR D CG2 1 
ATOM   8634 N  N   . LEU D 2 217 ? -55.275 -23.351 18.064  1   34.41  ? 387 LEU D N   1 
ATOM   8635 C  CA  . LEU D 2 217 ? -54.933 -23.604 19.454  1   32.09  ? 387 LEU D CA  1 
ATOM   8636 C  C   . LEU D 2 217 ? -54.842 -25.089 19.794  1   32.62  ? 387 LEU D C   1 
ATOM   8637 O  O   . LEU D 2 217 ? -54.409 -25.44  20.886  1   36.36  ? 387 LEU D O   1 
ATOM   8638 C  CB  . LEU D 2 217 ? -55.991 -22.965 20.357  1   30.06  ? 387 LEU D CB  1 
ATOM   8639 C  CG  . LEU D 2 217 ? -56.159 -21.468 20.222  1   30.03  ? 387 LEU D CG  1 
ATOM   8640 C  CD1 . LEU D 2 217 ? -57.325 -20.971 21.072  1   30.82  ? 387 LEU D CD1 1 
ATOM   8641 C  CD2 . LEU D 2 217 ? -54.918 -20.739 20.621  1   28.97  ? 387 LEU D CD2 1 
ATOM   8642 N  N   . LYS D 2 218 ? -55.235 -25.955 18.87   1   33.37  ? 388 LYS D N   1 
ATOM   8643 C  CA  . LYS D 2 218 ? -55.297 -27.411 19.175  1   35.67  ? 388 LYS D CA  1 
ATOM   8644 C  C   . LYS D 2 218 ? -53.992 -27.928 19.803  1   34.55  ? 388 LYS D C   1 
ATOM   8645 O  O   . LYS D 2 218 ? -54.08  -28.493 20.902  1   34.75  ? 388 LYS D O   1 
ATOM   8646 C  CB  . LYS D 2 218 ? -55.704 -28.21  17.929  1   37.11  ? 388 LYS D CB  1 
ATOM   8647 C  CG  . LYS D 2 218 ? -55.87  -29.705 18.137  1   40.57  ? 388 LYS D CG  1 
ATOM   8648 C  CD  . LYS D 2 218 ? -56.321 -30.427 16.875  1   44.49  ? 388 LYS D CD  1 
ATOM   8649 C  CE  . LYS D 2 218 ? -56.451 -31.895 17.107  1   50.08  ? 388 LYS D CE  1 
ATOM   8650 N  NZ  . LYS D 2 218 ? -56.885 -32.605 15.901  1   54.07  ? 388 LYS D NZ  1 
ATOM   8651 N  N   . PRO D 2 219 ? -52.801 -27.809 19.181  1   32.3   ? 389 PRO D N   1 
ATOM   8652 C  CA  . PRO D 2 219 ? -51.608 -28.379 19.787  1   32.37  ? 389 PRO D CA  1 
ATOM   8653 C  C   . PRO D 2 219 ? -51.414 -27.968 21.238  1   34.86  ? 389 PRO D C   1 
ATOM   8654 O  O   . PRO D 2 219 ? -51.222 -28.854 22.088  1   37.14  ? 389 PRO D O   1 
ATOM   8655 C  CB  . PRO D 2 219 ? -50.508 -27.847 18.887  1   32.09  ? 389 PRO D CB  1 
ATOM   8656 C  CG  . PRO D 2 219 ? -51.179 -27.689 17.549  1   31.88  ? 389 PRO D CG  1 
ATOM   8657 C  CD  . PRO D 2 219 ? -52.543 -27.148 17.911  1   31.61  ? 389 PRO D CD  1 
ATOM   8658 N  N   . CYS D 2 220 ? -51.466 -26.662 21.52   1   35.11  ? 390 CYS D N   1 
ATOM   8659 C  CA  . CYS D 2 220 ? -51.236 -26.162 22.902  1   36.04  ? 390 CYS D CA  1 
ATOM   8660 C  C   . CYS D 2 220 ? -52.338 -26.7   23.819  1   34.3   ? 390 CYS D C   1 
ATOM   8661 O  O   . CYS D 2 220 ? -52.024 -27.084 24.952  1   31.48  ? 390 CYS D O   1 
ATOM   8662 C  CB  . CYS D 2 220 ? -51.171 -24.637 22.945  1   37.18  ? 390 CYS D CB  1 
ATOM   8663 S  SG  . CYS D 2 220 ? -50.673 -23.958 24.547  1   37.83  ? 390 CYS D SG  1 
ATOM   8664 N  N   . LEU D 2 221 ? -53.568 -26.742 23.322  1   35.87  ? 391 LEU D N   1 
ATOM   8665 C  CA  . LEU D 2 221 ? -54.697 -27.258 24.135  1   37.39  ? 391 LEU D CA  1 
ATOM   8666 C  C   . LEU D 2 221 ? -54.422 -28.72  24.505  1   36.59  ? 391 LEU D C   1 
ATOM   8667 O  O   . LEU D 2 221 ? -54.634 -29.086 25.67   1   35.19  ? 391 LEU D O   1 
ATOM   8668 C  CB  . LEU D 2 221 ? -56.016 -27.086 23.39   1   40.1   ? 391 LEU D CB  1 
ATOM   8669 C  CG  . LEU D 2 221 ? -57.248 -27.649 24.102  1   42.03  ? 391 LEU D CG  1 
ATOM   8670 C  CD1 . LEU D 2 221 ? -57.494 -26.932 25.414  1   42.8   ? 391 LEU D CD1 1 
ATOM   8671 C  CD2 . LEU D 2 221 ? -58.455 -27.55  23.19   1   42.89  ? 391 LEU D CD2 1 
ATOM   8672 N  N   . LEU D 2 222 ? -53.931 -29.499 23.55   1   36.67  ? 392 LEU D N   1 
ATOM   8673 C  CA  . LEU D 2 222 ? -53.677 -30.934 23.812  1   38.07  ? 392 LEU D CA  1 
ATOM   8674 C  C   . LEU D 2 222 ? -52.625 -31.055 24.917  1   36.9   ? 392 LEU D C   1 
ATOM   8675 O  O   . LEU D 2 222 ? -52.83  -31.848 25.85   1   40.12  ? 392 LEU D O   1 
ATOM   8676 C  CB  . LEU D 2 222 ? -53.237 -31.624 22.526  1   36.93  ? 392 LEU D CB  1 
ATOM   8677 C  CG  . LEU D 2 222 ? -54.299 -31.708 21.427  1   37.13  ? 392 LEU D CG  1 
ATOM   8678 C  CD1 . LEU D 2 222 ? -53.822 -32.571 20.277  1   36.45  ? 392 LEU D CD1 1 
ATOM   8679 C  CD2 . LEU D 2 222 ? -55.61  -32.224 21.987  1   37.56  ? 392 LEU D CD2 1 
ATOM   8680 N  N   . ASP D 2 223 ? -51.553 -30.275 24.816  1   35.34  ? 393 ASP D N   1 
ATOM   8681 C  CA  . ASP D 2 223 ? -50.515 -30.351 25.831  1   34.5   ? 393 ASP D CA  1 
ATOM   8682 C  C   . ASP D 2 223 ? -51.056 -29.884 27.18   1   35.11  ? 393 ASP D C   1 
ATOM   8683 O  O   . ASP D 2 223 ? -50.84  -30.544 28.196  1   39.52  ? 393 ASP D O   1 
ATOM   8684 C  CB  . ASP D 2 223 ? -49.272 -29.536 25.433  1   35.08  ? 393 ASP D CB  1 
ATOM   8685 C  CG  . ASP D 2 223 ? -48.436 -30.162 24.328  1   33.2   ? 393 ASP D CG  1 
ATOM   8686 O  OD1 . ASP D 2 223 ? -48.275 -31.399 24.338  1   36.29  ? 393 ASP D OD1 1 
ATOM   8687 O  OD2 . ASP D 2 223 ? -47.907 -29.41  23.479  1   30.38  ? 393 ASP D OD2 1 
ATOM   8688 N  N   . LEU D 2 224 ? -51.77  -28.749 27.173  1   32.42  ? 394 LEU D N   1 
ATOM   8689 C  CA  . LEU D 2 224 ? -52.27  -28.139 28.394  1   32.38  ? 394 LEU D CA  1 
ATOM   8690 C  C   . LEU D 2 224 ? -53.339 -28.996 29.065  1   31.87  ? 394 LEU D C   1 
ATOM   8691 O  O   . LEU D 2 224 ? -53.446 -29.009 30.289  1   32.41  ? 394 LEU D O   1 
ATOM   8692 C  CB  . LEU D 2 224 ? -52.816 -26.73  28.095  1   33.74  ? 394 LEU D CB  1 
ATOM   8693 C  CG  . LEU D 2 224 ? -52.989 -25.808 29.303  1   33.7   ? 394 LEU D CG  1 
ATOM   8694 C  CD1 . LEU D 2 224 ? -51.656 -25.523 29.973  1   33.92  ? 394 LEU D CD1 1 
ATOM   8695 C  CD2 . LEU D 2 224 ? -53.657 -24.49  28.907  1   33.84  ? 394 LEU D CD2 1 
ATOM   8696 N  N   . HIS D 2 225 ? -54.117 -29.72  28.255  1   31.76  ? 395 HIS D N   1 
ATOM   8697 C  CA  . HIS D 2 225 ? -55.08  -30.676 28.774  1   31.04  ? 395 HIS D CA  1 
ATOM   8698 C  C   . HIS D 2 225 ? -54.363 -31.835 29.465  1   32.18  ? 395 HIS D C   1 
ATOM   8699 O  O   . HIS D 2 225 ? -54.793 -32.278 30.523  1   33.79  ? 395 HIS D O   1 
ATOM   8700 C  CB  . HIS D 2 225 ? -55.986 -31.204 27.651  1   30.33  ? 395 HIS D CB  1 
ATOM   8701 C  CG  . HIS D 2 225 ? -57.126 -32.058 28.129  1   29.44  ? 395 HIS D CG  1 
ATOM   8702 N  ND1 . HIS D 2 225 ? -57.679 -33.034 27.325  1   27.78  ? 395 HIS D ND1 1 
ATOM   8703 C  CD2 . HIS D 2 225 ? -57.748 -32.08  29.33   1   27.43  ? 395 HIS D CD2 1 
ATOM   8704 C  CE1 . HIS D 2 225 ? -58.633 -33.596 28.047  1   28.01  ? 395 HIS D CE1 1 
ATOM   8705 N  NE2 . HIS D 2 225 ? -58.702 -33.045 29.266  1   27.13  ? 395 HIS D NE2 1 
ATOM   8706 N  N   . GLN D 2 226 ? -53.273 -32.319 28.855  1   33.69  ? 396 GLN D N   1 
ATOM   8707 C  CA  . GLN D 2 226 ? -52.454 -33.368 29.445  1   36.89  ? 396 GLN D CA  1 
ATOM   8708 C  C   . GLN D 2 226 ? -51.871 -32.899 30.775  1   35.48  ? 396 GLN D C   1 
ATOM   8709 O  O   . GLN D 2 226 ? -51.891 -33.632 31.761  1   35.44  ? 396 GLN D O   1 
ATOM   8710 C  CB  . GLN D 2 226 ? -51.278 -33.797 28.526  1   41.66  ? 396 GLN D CB  1 
ATOM   8711 C  CG  . GLN D 2 226 ? -51.608 -34.654 27.311  1   46.12  ? 396 GLN D CG  1 
ATOM   8712 C  CD  . GLN D 2 226 ? -52.405 -35.905 27.621  1   53.36  ? 396 GLN D CD  1 
ATOM   8713 O  OE1 . GLN D 2 226 ? -52.057 -36.72  28.48   1   60.44  ? 396 GLN D OE1 1 
ATOM   8714 N  NE2 . GLN D 2 226 ? -53.508 -36.08  26.91   1   53.7   ? 396 GLN D NE2 1 
ATOM   8715 N  N   . THR D 2 227 ? -51.346 -31.671 30.789  1   33.58  ? 397 THR D N   1 
ATOM   8716 C  CA  . THR D 2 227 ? -50.745 -31.114 31.99   1   33.18  ? 397 THR D CA  1 
ATOM   8717 C  C   . THR D 2 227 ? -51.763 -31.047 33.129  1   33.69  ? 397 THR D C   1 
ATOM   8718 O  O   . THR D 2 227 ? -51.434 -31.376 34.27   1   33.3   ? 397 THR D O   1 
ATOM   8719 C  CB  . THR D 2 227 ? -50.135 -29.742 31.681  1   30.26  ? 397 THR D CB  1 
ATOM   8720 O  OG1 . THR D 2 227 ? -49.019 -29.929 30.808  1   27.45  ? 397 THR D OG1 1 
ATOM   8721 C  CG2 . THR D 2 227 ? -49.69  -29.009 32.939  1   29.95  ? 397 THR D CG2 1 
ATOM   8722 N  N   . TYR D 2 228 ? -52.989 -30.619 32.793  1   32.23  ? 398 TYR D N   1 
ATOM   8723 C  CA  . TYR D 2 228 ? -54.08  -30.49  33.747  1   32.72  ? 398 TYR D CA  1 
ATOM   8724 C  C   . TYR D 2 228 ? -54.429 -31.852 34.343  1   33.82  ? 398 TYR D C   1 
ATOM   8725 O  O   . TYR D 2 228 ? -54.56  -31.979 35.56   1   32.81  ? 398 TYR D O   1 
ATOM   8726 C  CB  . TYR D 2 228 ? -55.308 -29.851 33.04   1   32.16  ? 398 TYR D CB  1 
ATOM   8727 C  CG  . TYR D 2 228 ? -56.458 -29.371 33.913  1   31.24  ? 398 TYR D CG  1 
ATOM   8728 C  CD1 . TYR D 2 228 ? -56.33  -29.283 35.294  1   31.11  ? 398 TYR D CD1 1 
ATOM   8729 C  CD2 . TYR D 2 228 ? -57.676 -29.003 33.35   1   30.23  ? 398 TYR D CD2 1 
ATOM   8730 C  CE1 . TYR D 2 228 ? -57.386 -28.842 36.092  1   29.7   ? 398 TYR D CE1 1 
ATOM   8731 C  CE2 . TYR D 2 228 ? -58.745 -28.581 34.138  1   28.81  ? 398 TYR D CE2 1 
ATOM   8732 C  CZ  . TYR D 2 228 ? -58.595 -28.494 35.511  1   29.28  ? 398 TYR D CZ  1 
ATOM   8733 O  OH  . TYR D 2 228 ? -59.645 -28.06  36.291  1   27.83  ? 398 TYR D OH  1 
ATOM   8734 N  N   . LEU D 2 229 ? -54.559 -32.864 33.473  1   36.54  ? 399 LEU D N   1 
ATOM   8735 C  CA  . LEU D 2 229 ? -54.917 -34.211 33.895  1   37.22  ? 399 LEU D CA  1 
ATOM   8736 C  C   . LEU D 2 229 ? -53.849 -34.81  34.805  1   38.44  ? 399 LEU D C   1 
ATOM   8737 O  O   . LEU D 2 229 ? -54.175 -35.488 35.775  1   37.83  ? 399 LEU D O   1 
ATOM   8738 C  CB  . LEU D 2 229 ? -55.111 -35.149 32.689  1   35.4   ? 399 LEU D CB  1 
ATOM   8739 C  CG  . LEU D 2 229 ? -56.393 -34.974 31.89   1   34.97  ? 399 LEU D CG  1 
ATOM   8740 C  CD1 . LEU D 2 229 ? -56.355 -35.79  30.624  1   35.2   ? 399 LEU D CD1 1 
ATOM   8741 C  CD2 . LEU D 2 229 ? -57.622 -35.36  32.694  1   33.77  ? 399 LEU D CD2 1 
ATOM   8742 N  N   . ARG D 2 230 ? -52.576 -34.558 34.476  1   39.9   ? 400 ARG D N   1 
ATOM   8743 C  CA  . ARG D 2 230 ? -51.458 -35.154 35.192  1   41.39  ? 400 ARG D CA  1 
ATOM   8744 C  C   . ARG D 2 230 ? -51.023 -34.358 36.421  1   37.04  ? 400 ARG D C   1 
ATOM   8745 O  O   . ARG D 2 230 ? -50.204 -34.841 37.202  1   35.04  ? 400 ARG D O   1 
ATOM   8746 C  CB  . ARG D 2 230 ? -50.26  -35.322 34.232  1   45.97  ? 400 ARG D CB  1 
ATOM   8747 C  CG  . ARG D 2 230 ? -50.442 -36.508 33.27   1   49.48  ? 400 ARG D CG  1 
ATOM   8748 C  CD  . ARG D 2 230 ? -49.638 -36.378 31.981  1   52.28  ? 400 ARG D CD  1 
ATOM   8749 N  NE  . ARG D 2 230 ? -49.708 -37.604 31.186  1   53.66  ? 400 ARG D NE  1 
ATOM   8750 C  CZ  . ARG D 2 230 ? -49.851 -37.665 29.866  1   52.91  ? 400 ARG D CZ  1 
ATOM   8751 N  NH1 . ARG D 2 230 ? -49.549 -36.639 29.085  1   53.44  ? 400 ARG D NH1 1 
ATOM   8752 N  NH2 . ARG D 2 230 ? -50.269 -38.802 29.313  1   52.71  ? 400 ARG D NH2 1 
ATOM   8753 N  N   . ALA D 2 231 ? -51.589 -33.156 36.595  1   34.12  ? 401 ALA D N   1 
ATOM   8754 C  CA  . ALA D 2 231 ? -51.092 -32.204 37.578  1   32.77  ? 401 ALA D CA  1 
ATOM   8755 C  C   . ALA D 2 231 ? -50.984 -32.767 38.997  1   30.84  ? 401 ALA D C   1 
ATOM   8756 O  O   . ALA D 2 231 ? -49.996 -32.518 39.679  1   30.76  ? 401 ALA D O   1 
ATOM   8757 C  CB  . ALA D 2 231 ? -51.955 -30.94  37.568  1   32.29  ? 401 ALA D CB  1 
ATOM   8758 N  N   . PRO D 2 232 ? -51.969 -33.548 39.501  1   31.1   ? 402 PRO D N   1 
ATOM   8759 C  CA  . PRO D 2 232 ? -51.819 -34.203 40.806  1   31.11  ? 402 PRO D CA  1 
ATOM   8760 C  C   . PRO D 2 232 ? -50.58  -35.085 40.954  1   31.01  ? 402 PRO D C   1 
ATOM   8761 O  O   . PRO D 2 232 ? -50.108 -35.298 42.07   1   29.56  ? 402 PRO D O   1 
ATOM   8762 C  CB  . PRO D 2 232 ? -53.106 -35.033 40.936  1   29.5   ? 402 PRO D CB  1 
ATOM   8763 C  CG  . PRO D 2 232 ? -54.098 -34.38  40      1   29.52  ? 402 PRO D CG  1 
ATOM   8764 C  CD  . PRO D 2 232 ? -53.282 -33.8   38.875  1   30.04  ? 402 PRO D CD  1 
ATOM   8765 N  N   . GLN D 2 233 ? -50.076 -35.602 39.823  1   32.01  ? 403 GLN D N   1 
ATOM   8766 C  CA  . GLN D 2 233 ? -48.927 -36.494 39.806  1   32.82  ? 403 GLN D CA  1 
ATOM   8767 C  C   . GLN D 2 233 ? -47.588 -35.787 39.617  1   29.6   ? 403 GLN D C   1 
ATOM   8768 O  O   . GLN D 2 233 ? -46.545 -36.37  39.897  1   27.61  ? 403 GLN D O   1 
ATOM   8769 C  CB  . GLN D 2 233 ? -49.071 -37.546 38.675  1   34.69  ? 403 GLN D CB  1 
ATOM   8770 C  CG  . GLN D 2 233 ? -50.442 -38.224 38.572  1   33.15  ? 403 GLN D CG  1 
ATOM   8771 C  CD  . GLN D 2 233 ? -50.949 -38.749 39.888  1   33.71  ? 403 GLN D CD  1 
ATOM   8772 O  OE1 . GLN D 2 233 ? -50.305 -39.56  40.562  1   33.13  ? 403 GLN D OE1 1 
ATOM   8773 N  NE2 . GLN D 2 233 ? -52.131 -38.315 40.282  1   34.5   ? 403 GLN D NE2 1 
ATOM   8774 N  N   . HIS D 2 234 ? -47.615 -34.544 39.122  1   29.83  ? 404 HIS D N   1 
ATOM   8775 C  CA  . HIS D 2 234 ? -46.393 -33.819 38.817  1   28.01  ? 404 HIS D CA  1 
ATOM   8776 C  C   . HIS D 2 234 ? -45.529 -33.739 40.075  1   26.22  ? 404 HIS D C   1 
ATOM   8777 O  O   . HIS D 2 234 ? -46.059 -33.627 41.17   1   25.63  ? 404 HIS D O   1 
ATOM   8778 C  CB  . HIS D 2 234 ? -46.729 -32.417 38.274  1   29.95  ? 404 HIS D CB  1 
ATOM   8779 C  CG  . HIS D 2 234 ? -45.606 -31.74  37.541  1   30.43  ? 404 HIS D CG  1 
ATOM   8780 N  ND1 . HIS D 2 234 ? -44.44  -31.349 38.181  1   30.74  ? 404 HIS D ND1 1 
ATOM   8781 C  CD2 . HIS D 2 234 ? -45.517 -31.396 36.24   1   30.41  ? 404 HIS D CD2 1 
ATOM   8782 C  CE1 . HIS D 2 234 ? -43.682 -30.786 37.249  1   31.86  ? 404 HIS D CE1 1 
ATOM   8783 N  NE2 . HIS D 2 234 ? -44.292 -30.809 36.061  1   32.47  ? 404 HIS D NE2 1 
ATOM   8784 N  N   . ALA D 2 235 ? -44.203 -33.801 39.918  1   25.93  ? 405 ALA D N   1 
ATOM   8785 C  CA  . ALA D 2 235 ? -43.292 -33.674 41.047  1   26.51  ? 405 ALA D CA  1 
ATOM   8786 C  C   . ALA D 2 235 ? -43.421 -32.321 41.749  1   27.73  ? 405 ALA D C   1 
ATOM   8787 O  O   . ALA D 2 235 ? -43.304 -32.254 42.97   1   30.58  ? 405 ALA D O   1 
ATOM   8788 C  CB  . ALA D 2 235 ? -41.854 -33.898 40.599  1   25.69  ? 405 ALA D CB  1 
ATOM   8789 N  N   . GLN D 2 236 ? -43.683 -31.257 40.978  1   27.51  ? 406 GLN D N   1 
ATOM   8790 C  CA  . GLN D 2 236 ? -43.891 -29.919 41.522  1   30.09  ? 406 GLN D CA  1 
ATOM   8791 C  C   . GLN D 2 236 ? -45.368 -29.601 41.774  1   30.71  ? 406 GLN D C   1 
ATOM   8792 O  O   . GLN D 2 236 ? -46.196 -29.713 40.875  1   31.56  ? 406 GLN D O   1 
ATOM   8793 C  CB  . GLN D 2 236 ? -43.288 -28.863 40.579  1   32.64  ? 406 GLN D CB  1 
ATOM   8794 C  CG  . GLN D 2 236 ? -41.795 -28.626 40.788  1   33     ? 406 GLN D CG  1 
ATOM   8795 C  CD  . GLN D 2 236 ? -40.938 -29.817 40.472  1   36.92  ? 406 GLN D CD  1 
ATOM   8796 O  OE1 . GLN D 2 236 ? -40.123 -30.253 41.285  1   41.31  ? 406 GLN D OE1 1 
ATOM   8797 N  NE2 . GLN D 2 236 ? -41.075 -30.367 39.277  1   39.48  ? 406 GLN D NE2 1 
ATOM   8798 N  N   . GLN D 2 237 ? -45.677 -29.173 43.005  1   31.31  ? 407 GLN D N   1 
ATOM   8799 C  CA  . GLN D 2 237 ? -47.045 -29.058 43.487  1   30.84  ? 407 GLN D CA  1 
ATOM   8800 C  C   . GLN D 2 237 ? -47.42  -27.701 44.085  1   30.34  ? 407 GLN D C   1 
ATOM   8801 O  O   . GLN D 2 237 ? -48.55  -27.536 44.546  1   31.27  ? 407 GLN D O   1 
ATOM   8802 C  CB  . GLN D 2 237 ? -47.273 -30.124 44.573  1   29.87  ? 407 GLN D CB  1 
ATOM   8803 C  CG  . GLN D 2 237 ? -47.259 -31.563 44.064  1   31.19  ? 407 GLN D CG  1 
ATOM   8804 C  CD  . GLN D 2 237 ? -48.445 -31.847 43.187  1   34.32  ? 407 GLN D CD  1 
ATOM   8805 O  OE1 . GLN D 2 237 ? -49.564 -31.467 43.501  1   37.54  ? 407 GLN D OE1 1 
ATOM   8806 N  NE2 . GLN D 2 237 ? -48.245 -32.507 42.063  1   36.09  ? 407 GLN D NE2 1 
ATOM   8807 N  N   . SER D 2 238 ? -46.494 -26.735 44.088  1   29.06  ? 408 SER D N   1 
ATOM   8808 C  CA  . SER D 2 238 ? -46.742 -25.465 44.759  1   31.49  ? 408 SER D CA  1 
ATOM   8809 C  C   . SER D 2 238 ? -47.917 -24.683 44.162  1   31.88  ? 408 SER D C   1 
ATOM   8810 O  O   . SER D 2 238 ? -48.639 -23.993 44.878  1   30.2   ? 408 SER D O   1 
ATOM   8811 C  CB  . SER D 2 238 ? -45.48  -24.596 44.758  1   30.02  ? 408 SER D CB  1 
ATOM   8812 O  OG  . SER D 2 238 ? -44.43  -25.219 45.47   1   28.25  ? 408 SER D OG  1 
ATOM   8813 N  N   . ILE D 2 239 ? -48.108 -24.805 42.844  1   33.4   ? 409 ILE D N   1 
ATOM   8814 C  CA  . ILE D 2 239 ? -49.188 -24.113 42.162  1   34.72  ? 409 ILE D CA  1 
ATOM   8815 C  C   . ILE D 2 239 ? -50.528 -24.742 42.539  1   36.91  ? 409 ILE D C   1 
ATOM   8816 O  O   . ILE D 2 239 ? -51.494 -24.027 42.815  1   38.46  ? 409 ILE D O   1 
ATOM   8817 C  CB  . ILE D 2 239 ? -48.946 -24.064 40.629  1   34.31  ? 409 ILE D CB  1 
ATOM   8818 C  CG1 . ILE D 2 239 ? -47.643 -23.32  40.294  1   34.81  ? 409 ILE D CG1 1 
ATOM   8819 C  CG2 . ILE D 2 239 ? -50.123 -23.423 39.906  1   34.1   ? 409 ILE D CG2 1 
ATOM   8820 C  CD1 . ILE D 2 239 ? -47.274 -23.35  38.873  1   36.12  ? 409 ILE D CD1 1 
ATOM   8821 N  N   . ARG D 2 240 ? -50.586 -26.077 42.579  1   37.23  ? 410 ARG D N   1 
ATOM   8822 C  CA  . ARG D 2 240 ? -51.814 -26.744 42.983  1   36.11  ? 410 ARG D CA  1 
ATOM   8823 C  C   . ARG D 2 240 ? -52.214 -26.342 44.398  1   35.39  ? 410 ARG D C   1 
ATOM   8824 O  O   . ARG D 2 240 ? -53.381 -26.052 44.64   1   34.21  ? 410 ARG D O   1 
ATOM   8825 C  CB  . ARG D 2 240 ? -51.699 -28.265 42.89   1   33.53  ? 410 ARG D CB  1 
ATOM   8826 C  CG  . ARG D 2 240 ? -51.856 -28.772 41.487  1   32.5   ? 410 ARG D CG  1 
ATOM   8827 C  CD  . ARG D 2 240 ? -51.987 -30.27  41.445  1   32.84  ? 410 ARG D CD  1 
ATOM   8828 N  NE  . ARG D 2 240 ? -53.294 -30.725 41.904  1   31.58  ? 410 ARG D NE  1 
ATOM   8829 C  CZ  . ARG D 2 240 ? -53.488 -31.538 42.932  1   30.12  ? 410 ARG D CZ  1 
ATOM   8830 N  NH1 . ARG D 2 240 ? -52.481 -31.995 43.656  1   29.44  ? 410 ARG D NH1 1 
ATOM   8831 N  NH2 . ARG D 2 240 ? -54.728 -31.891 43.252  1   29.61  ? 410 ARG D NH2 1 
ATOM   8832 N  N   . GLU D 2 241 ? -51.237 -26.318 45.31   1   35.44  ? 411 GLU D N   1 
ATOM   8833 C  CA  . GLU D 2 241 ? -51.495 -25.922 46.685  1   36.96  ? 411 GLU D CA  1 
ATOM   8834 C  C   . GLU D 2 241 ? -52.001 -24.484 46.756  1   35.07  ? 411 GLU D C   1 
ATOM   8835 O  O   . GLU D 2 241 ? -53     -24.208 47.413  1   35.46  ? 411 GLU D O   1 
ATOM   8836 C  CB  . GLU D 2 241 ? -50.242 -26.107 47.559  1   37.61  ? 411 GLU D CB  1 
ATOM   8837 C  CG  . GLU D 2 241 ? -49.891 -27.568 47.837  1   40.56  ? 411 GLU D CG  1 
ATOM   8838 C  CD  . GLU D 2 241 ? -51.034 -28.416 48.386  1   42.21  ? 411 GLU D CD  1 
ATOM   8839 O  OE1 . GLU D 2 241 ? -51.744 -27.95  49.306  1   45.89  ? 411 GLU D OE1 1 
ATOM   8840 O  OE2 . GLU D 2 241 ? -51.212 -29.551 47.894  1   39.36  ? 411 GLU D OE2 1 
ATOM   8841 N  N   . LYS D 2 242 ? -51.319 -23.587 46.041  1   34.44  ? 412 LYS D N   1 
ATOM   8842 C  CA  . LYS D 2 242 ? -51.676 -22.177 46.006  1   34.6   ? 412 LYS D CA  1 
ATOM   8843 C  C   . LYS D 2 242 ? -53.125 -21.978 45.567  1   33.05  ? 412 LYS D C   1 
ATOM   8844 O  O   . LYS D 2 242 ? -53.862 -21.217 46.19   1   31.89  ? 412 LYS D O   1 
ATOM   8845 C  CB  . LYS D 2 242 ? -50.678 -21.446 45.08   1   33.68  ? 412 LYS D CB  1 
ATOM   8846 C  CG  . LYS D 2 242 ? -51.007 -20.023 44.686  1   32.6   ? 412 LYS D CG  1 
ATOM   8847 C  CD  . LYS D 2 242 ? -49.953 -19.487 43.699  1   31.98  ? 412 LYS D CD  1 
ATOM   8848 C  CE  . LYS D 2 242 ? -50.242 -18.097 43.154  1   30.97  ? 412 LYS D CE  1 
ATOM   8849 N  NZ  . LYS D 2 242 ? -49.213 -17.682 42.163  1   28.47  ? 412 LYS D NZ  1 
ATOM   8850 N  N   . TYR D 2 243 ? -53.531 -22.686 44.506  1   32.07  ? 413 TYR D N   1 
ATOM   8851 C  CA  . TYR D 2 243 ? -54.867 -22.52  43.952  1   32.99  ? 413 TYR D CA  1 
ATOM   8852 C  C   . TYR D 2 243 ? -55.961 -23.362 44.626  1   31.73  ? 413 TYR D C   1 
ATOM   8853 O  O   . TYR D 2 243 ? -57.109 -23.337 44.185  1   31.46  ? 413 TYR D O   1 
ATOM   8854 C  CB  . TYR D 2 243 ? -54.832 -22.747 42.413  1   31.86  ? 413 TYR D CB  1 
ATOM   8855 C  CG  . TYR D 2 243 ? -54.296 -21.549 41.661  1   32.14  ? 413 TYR D CG  1 
ATOM   8856 C  CD1 . TYR D 2 243 ? -52.926 -21.308 41.574  1   34.16  ? 413 TYR D CD1 1 
ATOM   8857 C  CD2 . TYR D 2 243 ? -55.153 -20.636 41.067  1   32     ? 413 TYR D CD2 1 
ATOM   8858 C  CE1 . TYR D 2 243 ? -52.424 -20.198 40.893  1   32.4   ? 413 TYR D CE1 1 
ATOM   8859 C  CE2 . TYR D 2 243 ? -54.663 -19.521 40.386  1   31.27  ? 413 TYR D CE2 1 
ATOM   8860 C  CZ  . TYR D 2 243 ? -53.295 -19.309 40.302  1   31.77  ? 413 TYR D CZ  1 
ATOM   8861 O  OH  . TYR D 2 243 ? -52.797 -18.214 39.659  1   32.73  ? 413 TYR D OH  1 
ATOM   8862 N  N   . LYS D 2 244 ? -55.628 -24.071 45.714  1   32.65  ? 414 LYS D N   1 
ATOM   8863 C  CA  . LYS D 2 244 ? -56.638 -24.659 46.585  1   35.44  ? 414 LYS D CA  1 
ATOM   8864 C  C   . LYS D 2 244 ? -57.325 -23.614 47.457  1   38.84  ? 414 LYS D C   1 
ATOM   8865 O  O   . LYS D 2 244 ? -58.421 -23.853 47.966  1   36.95  ? 414 LYS D O   1 
ATOM   8866 C  CB  . LYS D 2 244 ? -56.043 -25.696 47.546  1   36.21  ? 414 LYS D CB  1 
ATOM   8867 C  CG  . LYS D 2 244 ? -55.552 -26.954 46.884  1   38.79  ? 414 LYS D CG  1 
ATOM   8868 C  CD  . LYS D 2 244 ? -55.046 -27.958 47.891  1   40.45  ? 414 LYS D CD  1 
ATOM   8869 C  CE  . LYS D 2 244 ? -54.516 -29.207 47.243  1   40.85  ? 414 LYS D CE  1 
ATOM   8870 N  NZ  . LYS D 2 244 ? -53.984 -30.15  48.26   1   42.35  ? 414 LYS D NZ  1 
ATOM   8871 N  N   . ASN D 2 245 ? -56.657 -22.471 47.654  1   41.14  ? 415 ASN D N   1 
ATOM   8872 C  CA  . ASN D 2 245 ? -57.138 -21.49  48.613  1   43.13  ? 415 ASN D CA  1 
ATOM   8873 C  C   . ASN D 2 245 ? -58.326 -20.693 48.08   1   41.86  ? 415 ASN D C   1 
ATOM   8874 O  O   . ASN D 2 245 ? -58.451 -20.466 46.875  1   42.24  ? 415 ASN D O   1 
ATOM   8875 C  CB  . ASN D 2 245 ? -56.011 -20.571 49.055  1   47.11  ? 415 ASN D CB  1 
ATOM   8876 C  CG  . ASN D 2 245 ? -54.905 -21.342 49.737  1   50.89  ? 415 ASN D CG  1 
ATOM   8877 O  OD1 . ASN D 2 245 ? -55.136 -22.098 50.693  1   59.87  ? 415 ASN D OD1 1 
ATOM   8878 N  ND2 . ASN D 2 245 ? -53.689 -21.196 49.245  1   49.94  ? 415 ASN D ND2 1 
ATOM   8879 N  N   . SER D 2 246 ? -59.199 -20.3   49.016  1   39     ? 416 SER D N   1 
ATOM   8880 C  CA  . SER D 2 246 ? -60.342 -19.44  48.758  1   37.86  ? 416 SER D CA  1 
ATOM   8881 C  C   . SER D 2 246 ? -60.049 -18.198 47.912  1   39.16  ? 416 SER D C   1 
ATOM   8882 O  O   . SER D 2 246 ? -60.91  -17.761 47.154  1   38.51  ? 416 SER D O   1 
ATOM   8883 C  CB  . SER D 2 246 ? -60.963 -19.03  50.098  1   35.39  ? 416 SER D CB  1 
ATOM   8884 O  OG  . SER D 2 246 ? -60.069 -18.249 50.872  1   36.67  ? 416 SER D OG  1 
ATOM   8885 N  N   . LYS D 2 247 ? -58.845 -17.63  48.044  1   41.11  ? 417 LYS D N   1 
ATOM   8886 C  CA  . LYS D 2 247 ? -58.434 -16.505 47.216  1   43.11  ? 417 LYS D CA  1 
ATOM   8887 C  C   . LYS D 2 247 ? -58.665 -16.77  45.726  1   44.68  ? 417 LYS D C   1 
ATOM   8888 O  O   . LYS D 2 247 ? -59.098 -15.872 45.002  1   43.12  ? 417 LYS D O   1 
ATOM   8889 C  CB  . LYS D 2 247 ? -56.948 -16.179 47.475  1   46.74  ? 417 LYS D CB  1 
ATOM   8890 C  CG  . LYS D 2 247 ? -56.375 -15.085 46.573  1   50.31  ? 417 LYS D CG  1 
ATOM   8891 C  CD  . LYS D 2 247 ? -55.005 -14.604 47.016  1   56.45  ? 417 LYS D CD  1 
ATOM   8892 C  CE  . LYS D 2 247 ? -54.629 -13.283 46.375  1   60.88  ? 417 LYS D CE  1 
ATOM   8893 N  NZ  . LYS D 2 247 ? -53.389 -12.709 46.969  1   62.93  ? 417 LYS D NZ  1 
ATOM   8894 N  N   . TYR D 2 248 ? -58.382 -18.009 45.285  1   44.73  ? 418 TYR D N   1 
ATOM   8895 C  CA  . TYR D 2 248 ? -58.562 -18.409 43.896  1   41.29  ? 418 TYR D CA  1 
ATOM   8896 C  C   . TYR D 2 248 ? -59.731 -19.377 43.711  1   41.67  ? 418 TYR D C   1 
ATOM   8897 O  O   . TYR D 2 248 ? -59.753 -20.146 42.75   1   38.83  ? 418 TYR D O   1 
ATOM   8898 C  CB  . TYR D 2 248 ? -57.259 -19.037 43.353  1   37.32  ? 418 TYR D CB  1 
ATOM   8899 C  CG  . TYR D 2 248 ? -56.047 -18.153 43.542  1   34.32  ? 418 TYR D CG  1 
ATOM   8900 C  CD1 . TYR D 2 248 ? -55.861 -17.013 42.765  1   33.42  ? 418 TYR D CD1 1 
ATOM   8901 C  CD2 . TYR D 2 248 ? -55.096 -18.443 44.51   1   32     ? 418 TYR D CD2 1 
ATOM   8902 C  CE1 . TYR D 2 248 ? -54.747 -16.197 42.938  1   32.59  ? 418 TYR D CE1 1 
ATOM   8903 C  CE2 . TYR D 2 248 ? -53.982 -17.642 44.691  1   30.2   ? 418 TYR D CE2 1 
ATOM   8904 C  CZ  . TYR D 2 248 ? -53.814 -16.508 43.912  1   32.45  ? 418 TYR D CZ  1 
ATOM   8905 O  OH  . TYR D 2 248 ? -52.721 -15.69  44.085  1   32.75  ? 418 TYR D OH  1 
ATOM   8906 N  N   . HIS D 2 249 ? -60.688 -19.341 44.652  1   41.71  ? 419 HIS D N   1 
ATOM   8907 C  CA  . HIS D 2 249 ? -61.923 -20.104 44.554  1   41.98  ? 419 HIS D CA  1 
ATOM   8908 C  C   . HIS D 2 249 ? -61.703 -21.616 44.501  1   37.58  ? 419 HIS D C   1 
ATOM   8909 O  O   . HIS D 2 249 ? -62.562 -22.354 44.025  1   36.86  ? 419 HIS D O   1 
ATOM   8910 C  CB  . HIS D 2 249 ? -62.741 -19.607 43.338  1   47.25  ? 419 HIS D CB  1 
ATOM   8911 C  CG  . HIS D 2 249 ? -62.963 -18.123 43.366  1   53.58  ? 419 HIS D CG  1 
ATOM   8912 N  ND1 . HIS D 2 249 ? -63.538 -17.507 44.468  1   55.98  ? 419 HIS D ND1 1 
ATOM   8913 C  CD2 . HIS D 2 249 ? -62.644 -17.169 42.458  1   55.41  ? 419 HIS D CD2 1 
ATOM   8914 C  CE1 . HIS D 2 249 ? -63.565 -16.208 44.197  1   56.04  ? 419 HIS D CE1 1 
ATOM   8915 N  NE2 . HIS D 2 249 ? -63.031 -15.958 42.996  1   53.95  ? 419 HIS D NE2 1 
ATOM   8916 N  N   . GLY D 2 250 ? -60.556 -22.064 45.024  1   36     ? 420 GLY D N   1 
ATOM   8917 C  CA  . GLY D 2 250 ? -60.236 -23.48  45.107  1   34.85  ? 420 GLY D CA  1 
ATOM   8918 C  C   . GLY D 2 250 ? -60.258 -24.233 43.78   1   32.55  ? 420 GLY D C   1 
ATOM   8919 O  O   . GLY D 2 250 ? -60.579 -25.419 43.764  1   34.23  ? 420 GLY D O   1 
ATOM   8920 N  N   . VAL D 2 251 ? -59.891 -23.551 42.688  1   30     ? 421 VAL D N   1 
ATOM   8921 C  CA  . VAL D 2 251 ? -60.036 -24.106 41.352  1   29.73  ? 421 VAL D CA  1 
ATOM   8922 C  C   . VAL D 2 251 ? -59.159 -25.334 41.111  1   30.81  ? 421 VAL D C   1 
ATOM   8923 O  O   . VAL D 2 251 ? -59.547 -26.22  40.347  1   31.53  ? 421 VAL D O   1 
ATOM   8924 C  CB  . VAL D 2 251 ? -59.802 -23.035 40.243  1   29.47  ? 421 VAL D CB  1 
ATOM   8925 C  CG1 . VAL D 2 251 ? -60.941 -22.017 40.21   1   30.75  ? 421 VAL D CG1 1 
ATOM   8926 C  CG2 . VAL D 2 251 ? -58.447 -22.341 40.378  1   28.2   ? 421 VAL D CG2 1 
ATOM   8927 N  N   . SER D 2 252 ? -58.003 -25.412 41.788  1   30     ? 422 SER D N   1 
ATOM   8928 C  CA  . SER D 2 252 ? -57.117 -26.549 41.601  1   30.55  ? 422 SER D CA  1 
ATOM   8929 C  C   . SER D 2 252 ? -57.768 -27.852 42.061  1   30.19  ? 422 SER D C   1 
ATOM   8930 O  O   . SER D 2 252 ? -57.297 -28.92  41.693  1   28.1   ? 422 SER D O   1 
ATOM   8931 C  CB  . SER D 2 252 ? -55.771 -26.352 42.306  1   30.14  ? 422 SER D CB  1 
ATOM   8932 O  OG  . SER D 2 252 ? -55.891 -26.391 43.717  1   31.2   ? 422 SER D OG  1 
ATOM   8933 N  N   . LEU D 2 253 ? -58.842 -27.751 42.859  1   32.65  ? 423 LEU D N   1 
ATOM   8934 C  CA  . LEU D 2 253 ? -59.584 -28.915 43.322  1   34.98  ? 423 LEU D CA  1 
ATOM   8935 C  C   . LEU D 2 253 ? -60.657 -29.394 42.346  1   33.43  ? 423 LEU D C   1 
ATOM   8936 O  O   . LEU D 2 253 ? -61.195 -30.478 42.529  1   29.93  ? 423 LEU D O   1 
ATOM   8937 C  CB  . LEU D 2 253 ? -60.26  -28.599 44.672  1   36.91  ? 423 LEU D CB  1 
ATOM   8938 C  CG  . LEU D 2 253 ? -59.313 -28.356 45.844  1   39.75  ? 423 LEU D CG  1 
ATOM   8939 C  CD1 . LEU D 2 253 ? -60.049 -27.831 47.054  1   38.86  ? 423 LEU D CD1 1 
ATOM   8940 C  CD2 . LEU D 2 253 ? -58.573 -29.636 46.218  1   39.82  ? 423 LEU D CD2 1 
ATOM   8941 N  N   . LEU D 2 254 ? -60.976 -28.585 41.325  1   35.35  ? 424 LEU D N   1 
ATOM   8942 C  CA  . LEU D 2 254 ? -61.963 -28.977 40.33   1   34.56  ? 424 LEU D CA  1 
ATOM   8943 C  C   . LEU D 2 254 ? -61.407 -30.142 39.518  1   35.05  ? 424 LEU D C   1 
ATOM   8944 O  O   . LEU D 2 254 ? -60.217 -30.18  39.218  1   36.4   ? 424 LEU D O   1 
ATOM   8945 C  CB  . LEU D 2 254 ? -62.334 -27.808 39.4    1   35.23  ? 424 LEU D CB  1 
ATOM   8946 C  CG  . LEU D 2 254 ? -63.182 -26.682 40.037  1   37.15  ? 424 LEU D CG  1 
ATOM   8947 C  CD1 . LEU D 2 254 ? -63.574 -25.631 39.006  1   37.66  ? 424 LEU D CD1 1 
ATOM   8948 C  CD2 . LEU D 2 254 ? -64.454 -27.224 40.722  1   35.84  ? 424 LEU D CD2 1 
ATOM   8949 N  N   . ASN D 2 255 ? -62.27  -31.108 39.184  1   36.48  ? 425 ASN D N   1 
ATOM   8950 C  CA  . ASN D 2 255 ? -61.841 -32.267 38.419  1   37.42  ? 425 ASN D CA  1 
ATOM   8951 C  C   . ASN D 2 255 ? -61.743 -31.898 36.943  1   38.21  ? 425 ASN D C   1 
ATOM   8952 O  O   . ASN D 2 255 ? -62.684 -31.339 36.384  1   39.31  ? 425 ASN D O   1 
ATOM   8953 C  CB  . ASN D 2 255 ? -62.781 -33.439 38.594  1   37.48  ? 425 ASN D CB  1 
ATOM   8954 C  CG  . ASN D 2 255 ? -62.775 -33.988 39.991  1   37.21  ? 425 ASN D CG  1 
ATOM   8955 O  OD1 . ASN D 2 255 ? -63.821 -34.248 40.593  1   37.73  ? 425 ASN D OD1 1 
ATOM   8956 N  ND2 . ASN D 2 255 ? -61.587 -34.185 40.535  1   38.15  ? 425 ASN D ND2 1 
ATOM   8957 N  N   . PRO D 2 256 ? -60.603 -32.185 36.275  1   35.83  ? 426 PRO D N   1 
ATOM   8958 C  CA  . PRO D 2 256 ? -60.438 -31.811 34.87   1   33.48  ? 426 PRO D CA  1 
ATOM   8959 C  C   . PRO D 2 256 ? -61.34  -32.664 33.975  1   32.55  ? 426 PRO D C   1 
ATOM   8960 O  O   . PRO D 2 256 ? -61.606 -33.829 34.281  1   28.73  ? 426 PRO D O   1 
ATOM   8961 C  CB  . PRO D 2 256 ? -58.957 -32.08  34.618  1   34.02  ? 426 PRO D CB  1 
ATOM   8962 C  CG  . PRO D 2 256 ? -58.569 -33.132 35.657  1   34     ? 426 PRO D CG  1 
ATOM   8963 C  CD  . PRO D 2 256 ? -59.43  -32.878 36.842  1   34.51  ? 426 PRO D CD  1 
ATOM   8964 N  N   . PRO D 2 257 ? -61.843 -32.116 32.844  1   31.99  ? 427 PRO D N   1 
ATOM   8965 C  CA  . PRO D 2 257 ? -62.683 -32.886 31.926  1   32.73  ? 427 PRO D CA  1 
ATOM   8966 C  C   . PRO D 2 257 ? -61.841 -33.899 31.161  1   33.97  ? 427 PRO D C   1 
ATOM   8967 O  O   . PRO D 2 257 ? -60.713 -33.603 30.776  1   34.84  ? 427 PRO D O   1 
ATOM   8968 C  CB  . PRO D 2 257 ? -63.26  -31.824 30.997  1   32.7   ? 427 PRO D CB  1 
ATOM   8969 C  CG  . PRO D 2 257 ? -62.191 -30.746 30.983  1   32.08  ? 427 PRO D CG  1 
ATOM   8970 C  CD  . PRO D 2 257 ? -61.607 -30.74  32.378  1   31.35  ? 427 PRO D CD  1 
ATOM   8971 N  N   . GLU D 2 258 ? -62.408 -35.093 30.956  1   35.16  ? 428 GLU D N   1 
ATOM   8972 C  CA  . GLU D 2 258 ? -61.681 -36.202 30.366  1   36.78  ? 428 GLU D CA  1 
ATOM   8973 C  C   . GLU D 2 258 ? -61.478 -36.031 28.861  1   36.03  ? 428 GLU D C   1 
ATOM   8974 O  O   . GLU D 2 258 ? -60.567 -36.631 28.302  1   35.28  ? 428 GLU D O   1 
ATOM   8975 C  CB  . GLU D 2 258 ? -62.427 -37.511 30.674  1   39.59  ? 428 GLU D CB  1 
ATOM   8976 C  CG  . GLU D 2 258 ? -62.438 -37.863 32.161  1   42.39  ? 428 GLU D CG  1 
ATOM   8977 C  CD  . GLU D 2 258 ? -63.411 -38.961 32.565  1   47.21  ? 428 GLU D CD  1 
ATOM   8978 O  OE1 . GLU D 2 258 ? -63.588 -39.911 31.769  1   49.85  ? 428 GLU D OE1 1 
ATOM   8979 O  OE2 . GLU D 2 258 ? -63.982 -38.888 33.678  1   51.75  ? 428 GLU D OE2 1 
ATOM   8980 N  N   . THR D 2 259 ? -62.325 -35.213 28.218  1   35.66  ? 429 THR D N   1 
ATOM   8981 C  CA  . THR D 2 259 ? -62.313 -35.016 26.774  1   37.31  ? 429 THR D CA  1 
ATOM   8982 C  C   . THR D 2 259 ? -62.659 -33.573 26.425  1   38.8   ? 429 THR D C   1 
ATOM   8983 O  O   . THR D 2 259 ? -63.323 -32.893 27.201  1   38.85  ? 429 THR D O   1 
ATOM   8984 C  CB  . THR D 2 259 ? -63.305 -36.006 26.111  1   39.5   ? 429 THR D CB  1 
ATOM   8985 O  OG1 . THR D 2 259 ? -62.765 -37.321 26.197  1   39.15  ? 429 THR D OG1 1 
ATOM   8986 C  CG2 . THR D 2 259 ? -63.614 -35.699 24.637  1   38.95  ? 429 THR D CG2 1 
ATOM   8987 N  N   . LEU D 2 260 ? -62.21  -33.126 25.245  1   41.61  ? 430 LEU D N   1 
ATOM   8988 C  CA  . LEU D 2 260 ? -62.434 -31.763 24.789  1   43.86  ? 430 LEU D CA  1 
ATOM   8989 C  C   . LEU D 2 260 ? -63.415 -31.628 23.623  1   48.27  ? 430 LEU D C   1 
ATOM   8990 O  O   . LEU D 2 260 ? -63.935 -30.54  23.395  1   50.66  ? 430 LEU D O   1 
ATOM   8991 C  CB  . LEU D 2 260 ? -61.093 -31.166 24.374  1   42.35  ? 430 LEU D CB  1 
ATOM   8992 C  CG  . LEU D 2 260 ? -60.034 -31.105 25.476  1   44.38  ? 430 LEU D CG  1 
ATOM   8993 C  CD1 . LEU D 2 260 ? -58.787 -30.44  24.982  1   45.57  ? 430 LEU D CD1 1 
ATOM   8994 C  CD2 . LEU D 2 260 ? -60.548 -30.368 26.714  1   44.04  ? 430 LEU D CD2 1 
ATOM   8995 N  N   . ASN D 2 261 ? -63.668 -32.722 22.892  1   50.8   ? 431 ASN D N   1 
ATOM   8996 C  CA  . ASN D 2 261 ? -64.567 -32.718 21.746  1   55.67  ? 431 ASN D CA  1 
ATOM   8997 C  C   . ASN D 2 261 ? -63.997 -31.895 20.594  1   58.33  ? 431 ASN D C   1 
ATOM   8998 O  O   . ASN D 2 261 ? -64.091 -30.671 20.592  1   59.97  ? 431 ASN D O   1 
ATOM   8999 C  CB  . ASN D 2 261 ? -65.996 -32.218 22.092  1   56.86  ? 431 ASN D CB  1 
ATOM   9000 C  CG  . ASN D 2 261 ? -66.862 -33.288 22.7    1   58.92  ? 431 ASN D CG  1 
ATOM   9001 O  OD1 . ASN D 2 261 ? -66.812 -34.454 22.288  1   57.74  ? 431 ASN D OD1 1 
ATOM   9002 N  ND2 . ASN D 2 261 ? -67.681 -32.933 23.681  1   59.85  ? 431 ASN D ND2 1 
ATOM   9003 N  N   . VAL D 2 262 ? -63.459 -32.602 19.593  1   60.83  ? 432 VAL D N   1 
ATOM   9004 C  CA  . VAL D 2 262 ? -62.825 -31.995 18.436  1   59.85  ? 432 VAL D CA  1 
ATOM   9005 C  C   . VAL D 2 262 ? -62.904 -33.004 17.258  1   60.32  ? 432 VAL D C   1 
ATOM   9006 O  O   . VAL D 2 262 ? -63.981 -33.539 16.97   1   55.9   ? 432 VAL D O   1 
ATOM   9007 C  CB  . VAL D 2 262 ? -61.368 -31.559 18.772  1   57.26  ? 432 VAL D CB  1 
ATOM   9008 C  CG1 . VAL D 2 262 ? -61.319 -30.194 19.467  1   56.73  ? 432 VAL D CG1 1 
ATOM   9009 C  CG2 . VAL D 2 262 ? -60.647 -32.629 19.6    1   55.2   ? 432 VAL D CG2 1 
HETATM 9010 C  C4  . HGQ E 3 .   ? -10.253 -20.812 22.631  0.5 34.05  ? 301 HGQ A C4  1 
HETATM 9011 C  C5  . HGQ E 3 .   ? -10.829 -21.746 23.431  0.5 30.11  ? 301 HGQ A C5  1 
HETATM 9012 N  N1  . HGQ E 3 .   ? -10.067 -22.452 24.3    0.5 31.57  ? 301 HGQ A N1  1 
HETATM 9013 C  C3  . HGQ E 3 .   ? -8.891  -20.594 22.711  0.5 36.43  ? 301 HGQ A C3  1 
HETATM 9014 O  O1  . HGQ E 3 .   ? -8.118  -22.975 25.265  0.5 33.8   ? 301 HGQ A O1  1 
HETATM 9015 C  C1  . HGQ E 3 .   ? -8.719  -22.285 24.431  0.5 31.48  ? 301 HGQ A C1  1 
HETATM 9016 C  C2  . HGQ E 3 .   ? -8.113  -21.308 23.588  0.5 32.06  ? 301 HGQ A C2  1 
HETATM 9017 BR BR1 . HGQ E 3 .   ? -8.087  -19.28  21.608  0.5 47.4   ? 301 HGQ A BR1 1 
HETATM 9018 C  C4  A HGQ F 3 .   ? 13.387  -24.393 -8.331  0.5 79.52  ? 302 HGQ A C4  1 
HETATM 9019 C  C4  B HGQ F 3 .   ? 14.911  -26.101 -7.786  0.5 165.11 ? 302 HGQ A C4  1 
HETATM 9020 C  C5  A HGQ F 3 .   ? 13.667  -23.672 -7.205  0.5 77.13  ? 302 HGQ A C5  1 
HETATM 9021 C  C5  B HGQ F 3 .   ? 15.293  -25.785 -6.515  0.5 163.08 ? 302 HGQ A C5  1 
HETATM 9022 N  N1  A HGQ F 3 .   ? 14.505  -24.175 -6.263  0.5 76.3   ? 302 HGQ A N1  1 
HETATM 9023 N  N1  B HGQ F 3 .   ? 14.817  -24.665 -5.918  0.5 161.21 ? 302 HGQ A N1  1 
HETATM 9024 C  C3  A HGQ F 3 .   ? 13.954  -25.644 -8.501  0.5 74.5   ? 302 HGQ A C3  1 
HETATM 9025 C  C3  B HGQ F 3 .   ? 14.035  -25.268 -8.458  0.5 166.42 ? 302 HGQ A C3  1 
HETATM 9026 O  O1  A HGQ F 3 .   ? 15.854  -25.775 -5.434  0.5 65     ? 302 HGQ A O1  1 
HETATM 9027 O  O1  B HGQ F 3 .   ? 13.561  -22.798 -5.884  0.5 146.09 ? 302 HGQ A O1  1 
HETATM 9028 C  C1  A HGQ F 3 .   ? 15.101  -25.4   -6.362  0.5 74.2   ? 302 HGQ A C1  1 
HETATM 9029 C  C1  B HGQ F 3 .   ? 13.943  -23.805 -6.519  0.5 160.44 ? 302 HGQ A C1  1 
HETATM 9030 C  C2  A HGQ F 3 .   ? 14.799  -26.162 -7.542  0.5 70.62  ? 302 HGQ A C2  1 
HETATM 9031 C  C2  B HGQ F 3 .   ? 13.546  -24.134 -7.854  0.5 164.88 ? 302 HGQ A C2  1 
HETATM 9032 BR BR1 A HGQ F 3 .   ? 13.551  -26.659 -10.061 0.5 71.31  ? 302 HGQ A BR1 1 
HETATM 9033 BR BR1 B HGQ F 3 .   ? 13.488  -25.68  -10.232 0.5 152.5  ? 302 HGQ A BR1 1 
HETATM 9034 C  C4  . HGQ G 3 .   ? -33.109 15.101  28.404  0.5 36.48  ? 301 HGQ C C4  1 
HETATM 9035 C  C5  . HGQ G 3 .   ? -32.844 15.827  27.313  0.5 34.21  ? 301 HGQ C C5  1 
HETATM 9036 N  N1  . HGQ G 3 .   ? -32.467 17.119  27.423  0.5 33.91  ? 301 HGQ C N1  1 
HETATM 9037 C  C3  . HGQ G 3 .   ? -33.002 15.682  29.646  0.5 40.55  ? 301 HGQ C C3  1 
HETATM 9038 O  O1  . HGQ G 3 .   ? -31.978 18.958  28.578  0.5 29.26  ? 301 HGQ C O1  1 
HETATM 9039 C  C1  . HGQ G 3 .   ? -32.338 17.77   28.608  0.5 34.03  ? 301 HGQ C C1  1 
HETATM 9040 C  C2  . HGQ G 3 .   ? -32.623 16.999  29.78   0.5 38.31  ? 301 HGQ C C2  1 
HETATM 9041 BR BR1 . HGQ G 3 .   ? -33.403 14.624  31.166  0.5 50.72  ? 301 HGQ C BR1 1 
HETATM 9042 O  O   . HOH H 4 .   ? 2.068   -29.658 12.953  1   48.23  ? 401 HOH A O   1 
HETATM 9043 O  O   . HOH H 4 .   ? -2.236  -21.015 16.292  1   58.15  ? 402 HOH A O   1 
HETATM 9044 O  O   . HOH H 4 .   ? -0.933  -25.285 -18.837 1   52.85  ? 403 HOH A O   1 
HETATM 9045 O  O   . HOH H 4 .   ? -12.747 -28.67  -5.208  1   33.66  ? 404 HOH A O   1 
HETATM 9046 O  O   . HOH H 4 .   ? 4.027   -20.701 -0.934  1   45.12  ? 405 HOH A O   1 
HETATM 9047 O  O   . HOH H 4 .   ? -16.358 -38.89  -3.251  1   50.8   ? 406 HOH A O   1 
HETATM 9048 O  O   . HOH H 4 .   ? 4.728   -19.599 -5.195  1   50.91  ? 407 HOH A O   1 
HETATM 9049 O  O   . HOH H 4 .   ? -19.689 -10.142 33.088  1   49.62  ? 408 HOH A O   1 
HETATM 9050 O  O   . HOH H 4 .   ? -22.059 -17.861 31.6    1   38.29  ? 409 HOH A O   1 
HETATM 9051 O  O   . HOH H 4 .   ? -12.706 -50.058 4.266   1   52.99  ? 410 HOH A O   1 
HETATM 9052 O  O   . HOH H 4 .   ? -6.999  -13.012 8.124   1   34.59  ? 411 HOH A O   1 
HETATM 9053 O  O   . HOH H 4 .   ? -17.006 -22.431 27.951  1   50.39  ? 412 HOH A O   1 
HETATM 9054 O  O   . HOH H 4 .   ? -22.033 -18.767 27.808  1   48.77  ? 413 HOH A O   1 
HETATM 9055 O  O   . HOH H 4 .   ? -14.389 -46.067 -0.453  1   55.59  ? 414 HOH A O   1 
HETATM 9056 O  O   . HOH H 4 .   ? 15.427  -31.275 -14.038 1   41.61  ? 415 HOH A O   1 
HETATM 9057 O  O   . HOH H 4 .   ? -15.236 -27.419 1.151   1   32.92  ? 416 HOH A O   1 
HETATM 9058 O  O   . HOH H 4 .   ? -22.774 -26.786 4.622   1   44.44  ? 417 HOH A O   1 
HETATM 9059 O  O   . HOH H 4 .   ? -26.741 -20.078 8.165   1   55.5   ? 418 HOH A O   1 
HETATM 9060 O  O   . HOH H 4 .   ? -3.057  -36.377 -5.572  1   51.93  ? 419 HOH A O   1 
HETATM 9061 O  O   . HOH H 4 .   ? 0.212   -33.527 8.315   1   37.23  ? 420 HOH A O   1 
HETATM 9062 O  O   . HOH H 4 .   ? -9.563  -47.001 -1.899  1   54.21  ? 421 HOH A O   1 
HETATM 9063 O  O   . HOH H 4 .   ? -5.158  -15.814 -4.567  1   45.11  ? 422 HOH A O   1 
HETATM 9064 O  O   . HOH H 4 .   ? -12.529 -10.217 2.862   1   36.18  ? 423 HOH A O   1 
HETATM 9065 O  O   . HOH H 4 .   ? -19.739 -11.006 3.228   1   44.94  ? 424 HOH A O   1 
HETATM 9066 O  O   . HOH H 4 .   ? -14.153 -27.212 -1.493  1   30.31  ? 425 HOH A O   1 
HETATM 9067 O  O   . HOH H 4 .   ? -18.572 -10.631 40.057  1   62.16  ? 426 HOH A O   1 
HETATM 9068 O  O   . HOH H 4 .   ? -0.036  -27.559 20.582  1   62.69  ? 427 HOH A O   1 
HETATM 9069 O  O   . HOH H 4 .   ? 2.134   -15.484 -8.287  1   53.5   ? 428 HOH A O   1 
HETATM 9070 O  O   . HOH H 4 .   ? 5.304   -42.059 1.326   1   46.79  ? 429 HOH A O   1 
HETATM 9071 O  O   . HOH H 4 .   ? -2.558  -15.304 -3.491  1   35.46  ? 430 HOH A O   1 
HETATM 9072 O  O   . HOH H 4 .   ? -7.798  -16.566 -4.172  1   34.86  ? 431 HOH A O   1 
HETATM 9073 O  O   . HOH H 4 .   ? 1.848   -32.362 6.219   1   33.06  ? 432 HOH A O   1 
HETATM 9074 O  O   . HOH H 4 .   ? 3.366   -39.877 7.283   1   53.08  ? 433 HOH A O   1 
HETATM 9075 O  O   . HOH H 4 .   ? -3.638  -25.586 2.4     1   35.06  ? 434 HOH A O   1 
HETATM 9076 O  O   . HOH H 4 .   ? 1.131   -38.598 8.15    1   40.13  ? 435 HOH A O   1 
HETATM 9077 O  O   . HOH H 4 .   ? -21.822 -28.582 8.317   1   43.07  ? 436 HOH A O   1 
HETATM 9078 O  O   . HOH H 4 .   ? -4.792  -38.103 -4.624  1   57.45  ? 437 HOH A O   1 
HETATM 9079 O  O   . HOH H 4 .   ? -14.901 -11.873 -5.155  1   42.55  ? 438 HOH A O   1 
HETATM 9080 O  O   . HOH H 4 .   ? -11.365 -16.793 -9.366  1   47.37  ? 439 HOH A O   1 
HETATM 9081 O  O   . HOH H 4 .   ? -10.827 -10.711 38.775  1   64.79  ? 440 HOH A O   1 
HETATM 9082 O  O   . HOH H 4 .   ? -18.251 -18.136 17.317  1   40.5   ? 441 HOH A O   1 
HETATM 9083 O  O   . HOH H 4 .   ? -19.214 -24.491 19.447  1   30.35  ? 442 HOH A O   1 
HETATM 9084 O  O   . HOH H 4 .   ? -23.173 -34.722 2.403   1   46.94  ? 443 HOH A O   1 
HETATM 9085 O  O   . HOH H 4 .   ? -19.4   -21.375 17.138  1   43.86  ? 444 HOH A O   1 
HETATM 9086 O  O   . HOH H 4 .   ? -7.854  -23.633 -4.305  1   32.67  ? 445 HOH A O   1 
HETATM 9087 O  O   . HOH H 4 .   ? -7.626  -18.399 10.482  1   30.06  ? 446 HOH A O   1 
HETATM 9088 O  O   . HOH H 4 .   ? -4.311  -8.28   5.174   1   48.03  ? 447 HOH A O   1 
HETATM 9089 O  O   . HOH H 4 .   ? -12.292 -28.954 -2.387  1   38.38  ? 448 HOH A O   1 
HETATM 9090 O  O   . HOH H 4 .   ? 1.181   -29.504 2.293   1   35.26  ? 449 HOH A O   1 
HETATM 9091 O  O   . HOH H 4 .   ? -12.171 -12.594 -9.402  1   39.08  ? 450 HOH A O   1 
HETATM 9092 O  O   . HOH H 4 .   ? -16.83  -26.917 25.21   1   48.55  ? 451 HOH A O   1 
HETATM 9093 O  O   . HOH H 4 .   ? -6.048  -24.294 5.996   1   35.08  ? 452 HOH A O   1 
HETATM 9094 O  O   . HOH H 4 .   ? -22.399 -15.045 17.787  1   52.68  ? 453 HOH A O   1 
HETATM 9095 O  O   . HOH H 4 .   ? -19.62  -9.314  10.556  1   42.13  ? 454 HOH A O   1 
HETATM 9096 O  O   . HOH H 4 .   ? -8.098  -10.561 -8.201  1   47.55  ? 455 HOH A O   1 
HETATM 9097 O  O   . HOH H 4 .   ? -16.787 -32.734 -3.933  1   40.55  ? 456 HOH A O   1 
HETATM 9098 O  O   . HOH H 4 .   ? -8.077  -33.12  -13.165 1   52.95  ? 457 HOH A O   1 
HETATM 9099 O  O   . HOH H 4 .   ? -15.937 -41.78  -2.886  1   39     ? 458 HOH A O   1 
HETATM 9100 O  O   . HOH H 4 .   ? 2.83    -24.677 14.112  1   48.99  ? 459 HOH A O   1 
HETATM 9101 O  O   . HOH H 4 .   ? -12.292 -10.835 5.384   1   38.25  ? 460 HOH A O   1 
HETATM 9102 O  O   . HOH H 4 .   ? -3.333  -4.524  11.181  1   64.98  ? 461 HOH A O   1 
HETATM 9103 O  O   . HOH H 4 .   ? -21.968 -10.998 23.822  1   61.27  ? 462 HOH A O   1 
HETATM 9104 O  O   . HOH H 4 .   ? 4.672   -21.806 7.874   1   39.55  ? 463 HOH A O   1 
HETATM 9105 O  O   . HOH H 4 .   ? -10.324 -11.171 -10.095 1   45     ? 464 HOH A O   1 
HETATM 9106 O  O   . HOH H 4 .   ? -6.074  -25.223 -11.23  1   48.78  ? 465 HOH A O   1 
HETATM 9107 O  O   . HOH H 4 .   ? 0.363   -37.414 -10.047 1   38.45  ? 466 HOH A O   1 
HETATM 9108 O  O   . HOH H 4 .   ? 4.123   -41.255 3.643   1   44.49  ? 467 HOH A O   1 
HETATM 9109 O  O   . HOH H 4 .   ? -23.386 -29.451 10.28   1   42.49  ? 468 HOH A O   1 
HETATM 9110 O  O   . HOH H 4 .   ? 12.057  -22.48  -1.44   1   38.4   ? 469 HOH A O   1 
HETATM 9111 O  O   . HOH H 4 .   ? -4.8    -19.327 -10.432 1   43.15  ? 470 HOH A O   1 
HETATM 9112 O  O   . HOH H 4 .   ? -2.762  -7.713  11.91   1   61.1   ? 471 HOH A O   1 
HETATM 9113 O  O   . HOH H 4 .   ? -9.515  -52.348 3.485   1   52.86  ? 472 HOH A O   1 
HETATM 9114 O  O   . HOH H 4 .   ? 11.106  -21.121 1.552   1   61.06  ? 473 HOH A O   1 
HETATM 9115 O  O   . HOH H 4 .   ? -18.173 -24.075 31.476  1   42.85  ? 474 HOH A O   1 
HETATM 9116 O  O   . HOH H 4 .   ? -5.033  -42.843 -5.837  1   50.95  ? 475 HOH A O   1 
HETATM 9117 O  O   . HOH H 4 .   ? -8.882  -48.906 16.409  1   59.18  ? 476 HOH A O   1 
HETATM 9118 O  O   . HOH H 4 .   ? 0.099   -11.259 -1.473  1   45.44  ? 477 HOH A O   1 
HETATM 9119 O  O   . HOH H 4 .   ? 7.005   -20.112 3.217   1   57.76  ? 478 HOH A O   1 
HETATM 9120 O  O   . HOH H 4 .   ? 1.837   -50.853 2.688   1   52.94  ? 479 HOH A O   1 
HETATM 9121 O  O   . HOH H 4 .   ? 10.485  -37.344 0.833   1   43.77  ? 480 HOH A O   1 
HETATM 9122 O  O   . HOH H 4 .   ? -22.335 -43.683 1.638   1   55.35  ? 481 HOH A O   1 
HETATM 9123 O  O   . HOH H 4 .   ? -2.625  -19.269 -11.857 1   47.15  ? 482 HOH A O   1 
HETATM 9124 O  O   . HOH H 4 .   ? -9.603  -19.337 19.122  1   55.4   ? 483 HOH A O   1 
HETATM 9125 O  O   . HOH H 4 .   ? 10.913  -41.198 -10.73  1   54.42  ? 484 HOH A O   1 
HETATM 9126 O  O   . HOH H 4 .   ? -16.013 -43.987 -2.134  1   39.93  ? 485 HOH A O   1 
HETATM 9127 O  O   . HOH H 4 .   ? -24.578 -27.271 10.019  1   46.59  ? 486 HOH A O   1 
HETATM 9128 O  O   . HOH H 4 .   ? -7.585  -51.825 6.574   1   64.79  ? 487 HOH A O   1 
HETATM 9129 O  O   . HOH H 4 .   ? 13.211  -36.615 2.639   1   59.06  ? 488 HOH A O   1 
HETATM 9130 O  O   . HOH H 4 .   ? -27.207 -21.214 10.922  1   54.07  ? 489 HOH A O   1 
HETATM 9131 O  O   . HOH I 4 .   ? -30.207 -21.655 -0.299  1   55.92  ? 501 HOH B O   1 
HETATM 9132 O  O   . HOH I 4 .   ? -26.101 2.555   13.924  1   55.1   ? 502 HOH B O   1 
HETATM 9133 O  O   . HOH I 4 .   ? -21.548 4.643   -19.808 1   44.98  ? 503 HOH B O   1 
HETATM 9134 O  O   . HOH I 4 .   ? -8.599  2.22    17.031  1   47.66  ? 504 HOH B O   1 
HETATM 9135 O  O   . HOH I 4 .   ? -19.629 -12.941 -0.681  1   38.64  ? 505 HOH B O   1 
HETATM 9136 O  O   . HOH I 4 .   ? -34.26  1.527   -25.874 1   63.61  ? 506 HOH B O   1 
HETATM 9137 O  O   . HOH I 4 .   ? -16.146 -8.188  1.686   1   26.67  ? 507 HOH B O   1 
HETATM 9138 O  O   . HOH I 4 .   ? -22.327 -0.354  0.709   1   44.59  ? 508 HOH B O   1 
HETATM 9139 O  O   . HOH I 4 .   ? -36.565 -13.078 -4.035  1   41.01  ? 509 HOH B O   1 
HETATM 9140 O  O   . HOH I 4 .   ? -25.075 -5.104  3.531   1   44.86  ? 510 HOH B O   1 
HETATM 9141 O  O   . HOH I 4 .   ? -35.331 2.226   7.575   1   66.22  ? 511 HOH B O   1 
HETATM 9142 O  O   . HOH I 4 .   ? -32.375 -10.077 0.746   1   31.34  ? 512 HOH B O   1 
HETATM 9143 O  O   . HOH I 4 .   ? -13.868 -21.79  -12.059 1   51.9   ? 513 HOH B O   1 
HETATM 9144 O  O   . HOH I 4 .   ? -26.031 10.997  -0.67   1   36.28  ? 514 HOH B O   1 
HETATM 9145 O  O   . HOH I 4 .   ? -5.846  -6.243  5.873   1   40.93  ? 515 HOH B O   1 
HETATM 9146 O  O   . HOH I 4 .   ? -26.048 3.872   18.492  1   43.79  ? 516 HOH B O   1 
HETATM 9147 O  O   . HOH I 4 .   ? -13.591 -10.851 -0.234  1   32.26  ? 517 HOH B O   1 
HETATM 9148 O  O   . HOH I 4 .   ? -30.886 21.77   10.819  1   59.54  ? 518 HOH B O   1 
HETATM 9149 O  O   . HOH I 4 .   ? -30.274 -12.034 -5.27   1   42.15  ? 519 HOH B O   1 
HETATM 9150 O  O   . HOH I 4 .   ? -9.03   15.966  2.442   1   52     ? 520 HOH B O   1 
HETATM 9151 O  O   . HOH I 4 .   ? -26.323 15.679  11.73   1   48.39  ? 521 HOH B O   1 
HETATM 9152 O  O   . HOH I 4 .   ? -20.883 8.208   -17.83  1   44.42  ? 522 HOH B O   1 
HETATM 9153 O  O   . HOH I 4 .   ? -26.706 10.913  -11.988 1   50.84  ? 523 HOH B O   1 
HETATM 9154 O  O   . HOH I 4 .   ? -1.722  13.127  13.601  1   54.73  ? 524 HOH B O   1 
HETATM 9155 O  O   . HOH I 4 .   ? -17.565 -10.693 -5.117  1   48.6   ? 525 HOH B O   1 
HETATM 9156 O  O   . HOH I 4 .   ? -29.295 11.746  13.787  1   54.4   ? 526 HOH B O   1 
HETATM 9157 O  O   . HOH I 4 .   ? -10.97  -19.315 -12.17  1   49.77  ? 527 HOH B O   1 
HETATM 9158 O  O   . HOH I 4 .   ? -4.133  -4.493  -0.753  1   49.7   ? 528 HOH B O   1 
HETATM 9159 O  O   . HOH I 4 .   ? -16.835 -8.043  -4.009  1   54.03  ? 529 HOH B O   1 
HETATM 9160 O  O   . HOH I 4 .   ? -5.95   14.664  18.869  1   52.55  ? 530 HOH B O   1 
HETATM 9161 O  O   . HOH I 4 .   ? -27.756 -3.921  3.26    1   42.47  ? 531 HOH B O   1 
HETATM 9162 O  O   . HOH I 4 .   ? -21.652 11.403  -12.019 1   53.32  ? 532 HOH B O   1 
HETATM 9163 O  O   . HOH I 4 .   ? -24.13  -24.259 -4.374  1   39.84  ? 533 HOH B O   1 
HETATM 9164 O  O   . HOH I 4 .   ? -38.024 -10.765 -15.551 1   47.09  ? 534 HOH B O   1 
HETATM 9165 O  O   . HOH I 4 .   ? -6.199  -3.302  -3.932  1   37.64  ? 535 HOH B O   1 
HETATM 9166 O  O   . HOH I 4 .   ? -12.329 4.014   -5.917  1   40.68  ? 536 HOH B O   1 
HETATM 9167 O  O   . HOH I 4 .   ? -22.745 -2.035  -2.038  1   34.36  ? 537 HOH B O   1 
HETATM 9168 O  O   . HOH I 4 .   ? -19.268 21.102  12.187  1   46.11  ? 538 HOH B O   1 
HETATM 9169 O  O   . HOH I 4 .   ? -28.667 -24.003 -0.809  1   56.48  ? 539 HOH B O   1 
HETATM 9170 O  O   . HOH I 4 .   ? -26.935 5.381   -1.588  1   41.77  ? 540 HOH B O   1 
HETATM 9171 O  O   . HOH I 4 .   ? -25.937 1.763   -3.077  1   40.7   ? 541 HOH B O   1 
HETATM 9172 O  O   . HOH I 4 .   ? -16.35  14.835  -8.206  1   47.54  ? 542 HOH B O   1 
HETATM 9173 O  O   . HOH I 4 .   ? -24.465 16.577  -4.53   1   56.81  ? 543 HOH B O   1 
HETATM 9174 O  O   . HOH I 4 .   ? -19.151 10.261  -8.428  1   45.99  ? 544 HOH B O   1 
HETATM 9175 O  O   . HOH I 4 .   ? -24.656 -17.489 -9.54   1   58.06  ? 545 HOH B O   1 
HETATM 9176 O  O   . HOH I 4 .   ? -16.173 16.587  7.488   1   46.51  ? 546 HOH B O   1 
HETATM 9177 O  O   . HOH I 4 .   ? 0.38    11.57   8.228   1   51.93  ? 547 HOH B O   1 
HETATM 9178 O  O   . HOH I 4 .   ? -17.852 -1.204  -7.857  1   46.92  ? 548 HOH B O   1 
HETATM 9179 O  O   . HOH I 4 .   ? -32.815 -16.339 -3.606  1   36.44  ? 549 HOH B O   1 
HETATM 9180 O  O   . HOH I 4 .   ? -17.792 -12.908 -11.82  1   42.43  ? 550 HOH B O   1 
HETATM 9181 O  O   . HOH I 4 .   ? -28.986 17.211  0.269   1   60.64  ? 551 HOH B O   1 
HETATM 9182 O  O   . HOH I 4 .   ? -24.375 9.339   -8.618  1   44.48  ? 552 HOH B O   1 
HETATM 9183 O  O   . HOH I 4 .   ? -13.753 5.634   20.927  1   44.23  ? 553 HOH B O   1 
HETATM 9184 O  O   . HOH I 4 .   ? -29.789 18.791  8.02    1   55.79  ? 554 HOH B O   1 
HETATM 9185 O  O   . HOH I 4 .   ? -31.443 -17.814 -18.453 1   48.81  ? 555 HOH B O   1 
HETATM 9186 O  O   . HOH I 4 .   ? -12.022 -22.741 -10.583 1   45.57  ? 556 HOH B O   1 
HETATM 9187 O  O   . HOH I 4 .   ? -8.351  -22.914 -6.896  1   39.87  ? 557 HOH B O   1 
HETATM 9188 O  O   . HOH I 4 .   ? -22.084 3.655   -26.607 1   50.41  ? 558 HOH B O   1 
HETATM 9189 O  O   . HOH I 4 .   ? -19.337 10.205  -11.335 1   48.06  ? 559 HOH B O   1 
HETATM 9190 O  O   . HOH I 4 .   ? -18.186 -8.746  3.465   1   32.81  ? 560 HOH B O   1 
HETATM 9191 O  O   . HOH I 4 .   ? -23.739 -25.578 -8.352  1   55.31  ? 561 HOH B O   1 
HETATM 9192 O  O   . HOH I 4 .   ? -7.071  -20.773 -10.138 1   47.15  ? 562 HOH B O   1 
HETATM 9193 O  O   . HOH I 4 .   ? -30.715 16.091  2.544   1   46.04  ? 563 HOH B O   1 
HETATM 9194 O  O   . HOH I 4 .   ? -30.184 -20.89  -11.584 1   51.77  ? 564 HOH B O   1 
HETATM 9195 O  O   . HOH I 4 .   ? -36.898 -2.377  -7.436  1   37.97  ? 565 HOH B O   1 
HETATM 9196 O  O   . HOH I 4 .   ? -31.836 9.74    2.268   1   52.95  ? 566 HOH B O   1 
HETATM 9197 O  O   . HOH I 4 .   ? -29.57  11.917  -2.467  1   41.56  ? 567 HOH B O   1 
HETATM 9198 O  O   . HOH I 4 .   ? -35.395 -8.563  -1.419  1   39.19  ? 568 HOH B O   1 
HETATM 9199 O  O   . HOH I 4 .   ? -24.737 -14.118 11.266  1   53.8   ? 569 HOH B O   1 
HETATM 9200 O  O   . HOH I 4 .   ? -13.341 -5.409  -5.528  1   36.07  ? 570 HOH B O   1 
HETATM 9201 O  O   . HOH I 4 .   ? -25.785 -1.688  12.052  1   50.06  ? 571 HOH B O   1 
HETATM 9202 O  O   . HOH I 4 .   ? -23.014 -28.079 -6.977  1   60.46  ? 572 HOH B O   1 
HETATM 9203 O  O   . HOH I 4 .   ? -24.912 -24.592 -1.813  1   38.55  ? 573 HOH B O   1 
HETATM 9204 O  O   . HOH I 4 .   ? -23.361 20.391  0.836   1   56.56  ? 574 HOH B O   1 
HETATM 9205 O  O   . HOH I 4 .   ? -5.99   -6.491  -1.867  1   39.28  ? 575 HOH B O   1 
HETATM 9206 O  O   . HOH I 4 .   ? -21.913 10.611  -8.682  1   41.2   ? 576 HOH B O   1 
HETATM 9207 O  O   . HOH I 4 .   ? -29.493 -12.812 -20.914 1   64.61  ? 577 HOH B O   1 
HETATM 9208 O  O   . HOH I 4 .   ? -25.975 16.613  -8.337  1   52.05  ? 578 HOH B O   1 
HETATM 9209 O  O   . HOH I 4 .   ? -23.665 -19.256 -18.165 1   63.62  ? 579 HOH B O   1 
HETATM 9210 O  O   . HOH I 4 .   ? -11.434 -3.341  -7.799  1   53.03  ? 580 HOH B O   1 
HETATM 9211 O  O   . HOH I 4 .   ? -34.952 -3.475  -2.097  1   46.05  ? 581 HOH B O   1 
HETATM 9212 O  O   . HOH I 4 .   ? -32.802 -11.544 -23.491 1   55.63  ? 582 HOH B O   1 
HETATM 9213 O  O   . HOH I 4 .   ? -28.705 15.38   17.681  1   52.73  ? 583 HOH B O   1 
HETATM 9214 O  O   . HOH I 4 .   ? -19.791 -5.803  -26.706 1   50.8   ? 584 HOH B O   1 
HETATM 9215 O  O   . HOH I 4 .   ? -11.565 18.133  14.433  1   42.3   ? 585 HOH B O   1 
HETATM 9216 O  O   . HOH I 4 .   ? -13.336 19.009  13.068  1   58.01  ? 586 HOH B O   1 
HETATM 9217 O  O   . HOH I 4 .   ? -29.8   -12.536 10.713  1   59.17  ? 587 HOH B O   1 
HETATM 9218 O  O   . HOH I 4 .   ? -28.083 -19.224 6.156   1   48.79  ? 588 HOH B O   1 
HETATM 9219 O  O   . HOH I 4 .   ? -33.762 -12.848 3.129   1   41     ? 589 HOH B O   1 
HETATM 9220 O  O   . HOH I 4 .   ? -24.061 -28.576 -4.812  1   63.56  ? 590 HOH B O   1 
HETATM 9221 O  O   . HOH I 4 .   ? -16.966 15.534  4.538   1   53.55  ? 591 HOH B O   1 
HETATM 9222 O  O   . HOH I 4 .   ? -28.941 11.461  -10.77  1   53.26  ? 592 HOH B O   1 
HETATM 9223 O  O   . HOH I 4 .   ? -24.231 10.112  -11.367 1   43.11  ? 593 HOH B O   1 
HETATM 9224 O  O   . HOH I 4 .   ? -35.032 -9.481  1.078   1   45.19  ? 594 HOH B O   1 
HETATM 9225 O  O   . HOH I 4 .   ? -37.895 -9.468  -2.126  1   50     ? 595 HOH B O   1 
HETATM 9226 O  O   . HOH I 4 .   ? -27.575 -1.626  2.103   1   52.36  ? 596 HOH B O   1 
HETATM 9227 O  O   . HOH I 4 .   ? -15.856 -11.253 -10.751 1   42.22  ? 597 HOH B O   1 
HETATM 9228 O  O   . HOH J 4 .   ? -27.371 10.378  18.048  1   43.82  ? 401 HOH C O   1 
HETATM 9229 O  O   . HOH J 4 .   ? -28.784 16.183  21.096  1   57.92  ? 402 HOH C O   1 
HETATM 9230 O  O   . HOH J 4 .   ? -44.052 24.745  17.041  1   46.74  ? 403 HOH C O   1 
HETATM 9231 O  O   . HOH J 4 .   ? -54.446 10.744  49.591  1   52.03  ? 404 HOH C O   1 
HETATM 9232 O  O   . HOH J 4 .   ? -22.908 11.056  17.965  1   40.75  ? 405 HOH C O   1 
HETATM 9233 O  O   . HOH J 4 .   ? -19.236 4.521   26.077  1   53.82  ? 406 HOH C O   1 
HETATM 9234 O  O   . HOH J 4 .   ? -45.618 24.189  38.177  1   55.9   ? 407 HOH C O   1 
HETATM 9235 O  O   . HOH J 4 .   ? -45.759 -2.351  35.481  1   39.34  ? 408 HOH C O   1 
HETATM 9236 O  O   . HOH J 4 .   ? -47.419 11.426  15.839  1   52.14  ? 409 HOH C O   1 
HETATM 9237 O  O   . HOH J 4 .   ? -54.534 2.034   38.781  1   52.32  ? 410 HOH C O   1 
HETATM 9238 O  O   . HOH J 4 .   ? -41.185 37.927  29.065  1   60.26  ? 411 HOH C O   1 
HETATM 9239 O  O   . HOH J 4 .   ? -58.866 10.358  29.142  1   45.85  ? 412 HOH C O   1 
HETATM 9240 O  O   . HOH J 4 .   ? -52.926 13.723  37.073  1   43.54  ? 413 HOH C O   1 
HETATM 9241 O  O   . HOH J 4 .   ? -38.307 8.823   21.345  1   46.15  ? 414 HOH C O   1 
HETATM 9242 O  O   . HOH J 4 .   ? -22.964 10.972  21.542  1   47.78  ? 415 HOH C O   1 
HETATM 9243 O  O   . HOH J 4 .   ? -39.338 0.119   44.232  1   51.8   ? 416 HOH C O   1 
HETATM 9244 O  O   . HOH J 4 .   ? -55.34  9.107   26.567  1   46.23  ? 417 HOH C O   1 
HETATM 9245 O  O   . HOH J 4 .   ? -37.624 11.97   19.919  1   47.39  ? 418 HOH C O   1 
HETATM 9246 O  O   . HOH J 4 .   ? -52.531 23.249  38.132  1   46.63  ? 419 HOH C O   1 
HETATM 9247 O  O   . HOH J 4 .   ? -51.546 24.162  35.633  1   45.6   ? 420 HOH C O   1 
HETATM 9248 O  O   . HOH J 4 .   ? -42.473 1.084   42.721  1   51.5   ? 421 HOH C O   1 
HETATM 9249 O  O   . HOH J 4 .   ? -35.326 0.693   43.858  1   44.18  ? 422 HOH C O   1 
HETATM 9250 O  O   . HOH J 4 .   ? -46.616 17.337  14.97   1   54.06  ? 423 HOH C O   1 
HETATM 9251 O  O   . HOH J 4 .   ? -24.563 0.12    48.257  1   42.56  ? 424 HOH C O   1 
HETATM 9252 O  O   . HOH J 4 .   ? -57.485 8.218   27.713  1   42.23  ? 425 HOH C O   1 
HETATM 9253 O  O   . HOH J 4 .   ? -13.466 12.901  28.94   1   64.21  ? 426 HOH C O   1 
HETATM 9254 O  O   . HOH J 4 .   ? -42.604 9.441   34.765  1   34.63  ? 427 HOH C O   1 
HETATM 9255 O  O   . HOH J 4 .   ? -54.479 2.424   41.313  1   49.86  ? 428 HOH C O   1 
HETATM 9256 O  O   . HOH J 4 .   ? -58.036 7.536   35.83   1   40.69  ? 429 HOH C O   1 
HETATM 9257 O  O   . HOH J 4 .   ? -23.502 0.854   24.439  1   67.95  ? 430 HOH C O   1 
HETATM 9258 O  O   . HOH J 4 .   ? -54.832 19.083  39.625  1   41.55  ? 431 HOH C O   1 
HETATM 9259 O  O   . HOH J 4 .   ? -43.815 -0.827  34.869  1   36.78  ? 432 HOH C O   1 
HETATM 9260 O  O   . HOH J 4 .   ? -32.231 22.799  21.694  1   48.89  ? 433 HOH C O   1 
HETATM 9261 O  O   . HOH J 4 .   ? -50.643 6.496   19.156  1   48.98  ? 434 HOH C O   1 
HETATM 9262 O  O   . HOH J 4 .   ? -43.505 31.773  18.396  1   57.07  ? 435 HOH C O   1 
HETATM 9263 O  O   . HOH J 4 .   ? -63.999 33.516  22.492  1   67.38  ? 436 HOH C O   1 
HETATM 9264 O  O   . HOH J 4 .   ? -18.55  7.084   23.029  1   42.96  ? 437 HOH C O   1 
HETATM 9265 O  O   . HOH J 4 .   ? -28.061 -1.734  28.493  1   48.67  ? 438 HOH C O   1 
HETATM 9266 O  O   . HOH J 4 .   ? -54.533 23.898  53.437  1   55.14  ? 439 HOH C O   1 
HETATM 9267 O  O   . HOH J 4 .   ? -36.863 17.552  34.669  1   56.83  ? 440 HOH C O   1 
HETATM 9268 O  O   . HOH J 4 .   ? -49.151 3.335   47.067  1   54.73  ? 441 HOH C O   1 
HETATM 9269 O  O   . HOH J 4 .   ? -37.747 19.777  15.764  1   56.98  ? 442 HOH C O   1 
HETATM 9270 O  O   . HOH J 4 .   ? -62.442 3.482   44.756  1   51.75  ? 443 HOH C O   1 
HETATM 9271 O  O   . HOH J 4 .   ? -21.854 -0.252  28.661  1   45.52  ? 444 HOH C O   1 
HETATM 9272 O  O   . HOH J 4 .   ? -51.421 35      19.642  1   58.31  ? 445 HOH C O   1 
HETATM 9273 O  O   . HOH J 4 .   ? -23.319 2.18    21.748  1   63.43  ? 446 HOH C O   1 
HETATM 9274 O  O   . HOH J 4 .   ? -55.213 -4.865  41.659  1   60.83  ? 447 HOH C O   1 
HETATM 9275 O  O   . HOH J 4 .   ? -35.465 12.654  30.495  1   43.67  ? 448 HOH C O   1 
HETATM 9276 O  O   . HOH J 4 .   ? -15.489 15.294  30.908  1   56.34  ? 449 HOH C O   1 
HETATM 9277 O  O   . HOH J 4 .   ? -39.014 9.079   16.509  1   53.39  ? 450 HOH C O   1 
HETATM 9278 O  O   . HOH J 4 .   ? -30.122 23.348  29.637  1   59.25  ? 451 HOH C O   1 
HETATM 9279 O  O   . HOH J 4 .   ? -54.403 6.727   43.474  1   51.25  ? 452 HOH C O   1 
HETATM 9280 O  O   . HOH J 4 .   ? -17.713 -2.42   32.527  1   73.26  ? 453 HOH C O   1 
HETATM 9281 O  O   . HOH K 4 .   ? -29.219 -29.576 29.345  1   53.43  ? 501 HOH D O   1 
HETATM 9282 O  O   . HOH K 4 .   ? -43.962 -8.445  49.775  1   59.97  ? 502 HOH D O   1 
HETATM 9283 O  O   . HOH K 4 .   ? -47.619 -12.837 18.761  1   48.81  ? 503 HOH D O   1 
HETATM 9284 O  O   . HOH K 4 .   ? -27.204 -4.578  40.77   1   44.74  ? 504 HOH D O   1 
HETATM 9285 O  O   . HOH K 4 .   ? -50.297 -5.136  28.944  1   44.88  ? 505 HOH D O   1 
HETATM 9286 O  O   . HOH K 4 .   ? -45.948 -6.214  33.501  1   33.83  ? 506 HOH D O   1 
HETATM 9287 O  O   . HOH K 4 .   ? -43.404 -20.088 26.22   1   52.93  ? 507 HOH D O   1 
HETATM 9288 O  O   . HOH K 4 .   ? -46.227 -15.645 31.144  1   39.11  ? 508 HOH D O   1 
HETATM 9289 O  O   . HOH K 4 .   ? -42.509 -14.364 24.542  1   49.28  ? 509 HOH D O   1 
HETATM 9290 O  O   . HOH K 4 .   ? -28.583 -23.221 41.829  1   39.15  ? 510 HOH D O   1 
HETATM 9291 O  O   . HOH K 4 .   ? -38.7   -26.794 33.051  1   48.79  ? 511 HOH D O   1 
HETATM 9292 O  O   . HOH K 4 .   ? -48.053 -7.787  45.657  1   40.91  ? 512 HOH D O   1 
HETATM 9293 O  O   . HOH K 4 .   ? -33.559 -31.951 38.714  1   46.01  ? 513 HOH D O   1 
HETATM 9294 O  O   . HOH K 4 .   ? -40.992 -1.181  42.32   1   44.85  ? 514 HOH D O   1 
HETATM 9295 O  O   . HOH K 4 .   ? -36.209 -4.064  46.244  1   44.13  ? 515 HOH D O   1 
HETATM 9296 O  O   . HOH K 4 .   ? -42.626 -23.246 30.147  1   61.89  ? 516 HOH D O   1 
HETATM 9297 O  O   . HOH K 4 .   ? -45.903 -5.472  28.757  1   46.21  ? 517 HOH D O   1 
HETATM 9298 O  O   . HOH K 4 .   ? -46.669 -17.327 43.55   1   41.22  ? 518 HOH D O   1 
HETATM 9299 O  O   . HOH K 4 .   ? -46.326 -4.65   46.009  1   49.71  ? 519 HOH D O   1 
HETATM 9300 O  O   . HOH K 4 .   ? -25.286 -25.201 31.644  1   40.29  ? 520 HOH D O   1 
HETATM 9301 O  O   . HOH K 4 .   ? -49.058 -16.038 17.347  1   52.77  ? 521 HOH D O   1 
HETATM 9302 O  O   . HOH K 4 .   ? -40.709 -1.194  21.167  1   55.99  ? 522 HOH D O   1 
HETATM 9303 O  O   . HOH K 4 .   ? -48.78  -3.662  35.135  1   43.93  ? 523 HOH D O   1 
HETATM 9304 O  O   . HOH K 4 .   ? -22.484 -25.908 40.006  1   56.02  ? 524 HOH D O   1 
HETATM 9305 O  O   . HOH K 4 .   ? -28.902 -23.37  44.624  1   44.81  ? 525 HOH D O   1 
HETATM 9306 O  O   . HOH K 4 .   ? -52.821 -6.408  29.126  1   42.33  ? 526 HOH D O   1 
HETATM 9307 O  O   . HOH K 4 .   ? -44.448 -6.179  30.901  1   41.76  ? 527 HOH D O   1 
HETATM 9308 O  O   . HOH K 4 .   ? -43.584 -15.403 31.18   1   51.6   ? 528 HOH D O   1 
HETATM 9309 O  O   . HOH K 4 .   ? -51.405 -11.712 42.141  1   56.07  ? 529 HOH D O   1 
HETATM 9310 O  O   . HOH K 4 .   ? -22.299 -7.727  37.183  1   46.02  ? 530 HOH D O   1 
HETATM 9311 O  O   . HOH K 4 .   ? -45.293 -20.555 30.366  1   41.09  ? 531 HOH D O   1 
HETATM 9312 O  O   . HOH K 4 .   ? -50.016 -1.539  17.764  1   54.24  ? 532 HOH D O   1 
HETATM 9313 O  O   . HOH K 4 .   ? -40.01  -29.897 30.529  1   51.08  ? 533 HOH D O   1 
HETATM 9314 O  O   . HOH K 4 .   ? -35.057 -32.822 32.904  1   48.7   ? 534 HOH D O   1 
HETATM 9315 O  O   . HOH K 4 .   ? -43.856 -27.458 48.318  1   61.5   ? 535 HOH D O   1 
HETATM 9316 O  O   . HOH K 4 .   ? -27.746 -31.157 30.511  1   51.91  ? 536 HOH D O   1 
HETATM 9317 O  O   . HOH K 4 .   ? -28.553 -7.186  54.671  1   50.41  ? 537 HOH D O   1 
HETATM 9318 O  O   . HOH K 4 .   ? -20.198 -22.33  40.234  1   49.2   ? 538 HOH D O   1 
HETATM 9319 O  O   . HOH K 4 .   ? -47.985 -4.294  43.41   1   42.18  ? 539 HOH D O   1 
HETATM 9320 O  O   . HOH K 4 .   ? -45.838 -28.264 38.15   1   48.51  ? 540 HOH D O   1 
HETATM 9321 O  O   . HOH K 4 .   ? -43.448 -20.975 28.456  1   50.08  ? 541 HOH D O   1 
HETATM 9322 O  O   . HOH K 4 .   ? -46.881 -19.769 19.279  1   47.91  ? 542 HOH D O   1 
HETATM 9323 O  O   . HOH K 4 .   ? -33.103 -22.067 49.402  1   64.55  ? 543 HOH D O   1 
HETATM 9324 O  O   . HOH K 4 .   ? -31.076 -30.9   28.868  1   53.34  ? 544 HOH D O   1 
HETATM 9325 O  O   . HOH K 4 .   ? -38.62  -32.626 30.635  1   52.27  ? 545 HOH D O   1 
HETATM 9326 O  O   . HOH K 4 .   ? -58.961 5.41    26.636  1   48.65  ? 546 HOH D O   1 
HETATM 9327 O  O   . HOH K 4 .   ? -19.697 -12.106 42.25   1   59.72  ? 547 HOH D O   1 
HETATM 9328 O  O   . HOH K 4 .   ? -44.778 -17.768 29.767  1   42.14  ? 548 HOH D O   1 
# 
